LOCUS       DAPOXO010000001       180770 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPOXO010000001 DAPOXO010000000
VERSION     DAPOXO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 180770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 180770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..180770
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.001"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(114..2687)
                     /gene="clpB"
                     /locus_tag="ROH59_000001"
     CDS             complement(114..2687)
                     /gene="clpB"
                     /locus_tag="ROH59_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDX4802553.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
     gene            complement(2817..3548)
                     /gene="pgeF"
                     /locus_tag="ROH59_000002"
     CDS             complement(2817..3548)
                     /gene="pgeF"
                     /locus_tag="ROH59_000002"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HDX4802554.1"
                     /translation="MSKLIVPQWPLPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNP
                     DHVGENRKRLFAAGNLPSKPVWLEQVHGKDVLKLIGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGAEVREAFMAVDAKASTAFIQHGDKYLADIYQLARQRLASVGVEQIFGGDRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3545..4525)
                     /gene="rluD"
                     /locus_tag="ROH59_000003"
     CDS             complement(3545..4525)
                     /gene="rluD"
                     /locus_tag="ROH59_000003"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HDX4802555.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEEMRADFEEHKDEVDWL"
     gene            4660..5397
                     /gene="bamD"
                     /locus_tag="ROH59_000004"
     CDS             4660..5397
                     /gene="bamD"
                     /locus_tag="ROH59_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HDX4802556.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            5667..6008
                     /gene="raiA"
                     /locus_tag="ROH59_000005"
     CDS             5667..6008
                     /gene="raiA"
                     /locus_tag="ROH59_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDX4802557.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     misc_feature    6111..6236
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            6112..6159
                     /gene="pheL"
                     /locus_tag="ROH59_000006"
     CDS             6112..6159
                     /gene="pheL"
                     /locus_tag="ROH59_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HDX4802558.1"
                     /translation="MKHTPFFFAFFFTFP"
     gene            6258..7418
                     /gene="pheA"
                     /locus_tag="ROH59_000007"
     CDS             6258..7418
                     /gene="pheA"
                     /locus_tag="ROH59_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HDX4802559.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELVVEVGKAKLLSHR
                     PVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPHWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQRQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHSLIMTRLESRPIH
                     GNPWEEMFYLDIQANLESAEMQKALKELGEITRSMKVLGCYPSENVVPVDPT"
     gene            complement(7461..8582)
                     /gene="tyrA"
                     /locus_tag="ROH59_000008"
     CDS             complement(7461..8582)
                     /gene="tyrA"
                     /locus_tag="ROH59_000008"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HDX4802560.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLILSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ"
     gene            complement(8593..9663)
                     /gene="aroF"
                     /locus_tag="ROH59_000009"
     CDS             complement(8593..9663)
                     /gene="aroF"
                     /locus_tag="ROH59_000009"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HDX4802561.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKTI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGQLTARVA"
     gene            9873..10238
                     /locus_tag="ROH59_000010"
     CDS             9873..10238
                     /locus_tag="ROH59_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HDX4802562.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     SAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWRKGADENASTIRLN"
     gene            10385..10903
                     /locus_tag="ROH59_000011"
     CDS             10385..10903
                     /locus_tag="ROH59_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HDX4802563.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPGLSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAIISGCNGFYFGNESP
                     TFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            10893..12119
                     /gene="dgcN"
                     /locus_tag="ROH59_000012"
     CDS             10893..12119
                     /gene="dgcN"
                     /locus_tag="ROH59_000012"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HDX4802564.1"
                     /translation="MMDNDNSLHKRPTFKRALRNISMTSIFITMTLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTHKEPGDTFSNFISHWLFPAPIIQPIRHNSETIGEVRLTARDSSISHFIWFSL
                     AVLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDA
                     RKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIEHASAENLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            12135..12617
                     /locus_tag="ROH59_000013"
     CDS             12135..12617
                     /locus_tag="ROH59_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDX4802565.1"
                     /translation="MIKHLLAPLIFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     VLSLKRANVVADAWAMGGQIPRSNLITQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(12694..13041)
                     /gene="rplS"
                     /locus_tag="ROH59_000014"
     CDS             complement(12694..13041)
                     /gene="rplS"
                     /locus_tag="ROH59_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDX4802566.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(13083..13850)
                     /gene="trmD"
                     /locus_tag="ROH59_000015"
     CDS             complement(13083..13850)
                     /gene="trmD"
                     /locus_tag="ROH59_000015"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDX4802567.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTYD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            complement(13881..14429)
                     /gene="rimM"
                     /locus_tag="ROH59_000016"
     CDS             complement(13881..14429)
                     /gene="rimM"
                     /locus_tag="ROH59_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDX4802568.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            complement(14448..14696)
                     /gene="rpsP"
                     /locus_tag="ROH59_000017"
     CDS             complement(14448..14696)
                     /gene="rpsP"
                     /locus_tag="ROH59_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDX4802569.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            complement(14833..16194)
                     /gene="ffh"
                     /locus_tag="ROH59_000018"
     CDS             complement(14833..16194)
                     /gene="ffh"
                     /locus_tag="ROH59_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDX4802570.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            16361..17152
                     /locus_tag="ROH59_000019"
     CDS             16361..17152
                     /locus_tag="ROH59_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417102.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HDX4802571.1"
                     /translation="MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVC
                     HAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIFQQLIS"
     gene            17173..18459
                     /locus_tag="ROH59_000020"
     CDS             17173..18459
                     /locus_tag="ROH59_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDX4802572.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            complement(18513..19106)
                     /gene="grpE"
                     /locus_tag="ROH59_000021"
     CDS             complement(18513..19106)
                     /gene="grpE"
                     /locus_tag="ROH59_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDX4802573.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA"
     gene            19229..20107
                     /gene="nadK"
                     /locus_tag="ROH59_000022"
     CDS             19229..20107
                     /gene="nadK"
                     /locus_tag="ROH59_000022"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HDX4802574.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            20193..21854
                     /gene="recN"
                     /locus_tag="ROH59_000023"
     CDS             20193..21854
                     /gene="recN"
                     /locus_tag="ROH59_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDX4802575.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSQLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALETARALHQQRQHYANELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGYGHQHYFVSKE
                     TDGAMTETHMQSLDKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            22003..22344
                     /gene="bamE"
                     /locus_tag="ROH59_000024"
     CDS             22003..22344
                     /gene="bamE"
                     /locus_tag="ROH59_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HDX4802576.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(22406..22696)
                     /locus_tag="ROH59_000025"
     CDS             complement(22406..22696)
                     /locus_tag="ROH59_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HDX4802577.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDIVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(22686..23123)
                     /gene="ratA"
                     /locus_tag="ROH59_000026"
     CDS             complement(22686..23123)
                     /gene="ratA"
                     /locus_tag="ROH59_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010376629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HDX4802578.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTP
                     GQMTAAVDVSKAGISKTFTTRNQLTSNQSILMSLVDGPFKKLIGGWKFTPLSQDACRI
                     EFHLDFEFTNKLIELAFGRVFKELAANMVQAFTVRAKEVYSAR"
     gene            23294..23776
                     /gene="smpB"
                     /locus_tag="ROH59_000027"
     CDS             23294..23776
                     /gene="smpB"
                     /locus_tag="ROH59_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDX4802579.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            23991..24353
                     /gene="ssrA"
                     /locus_tag="ROH59_000028"
     tmRNA           23991..24353
                     /gene="ssrA"
                     /locus_tag="ROH59_000028"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            25037..26014
                     /gene="csiD"
                     /locus_tag="ROH59_000029"
     CDS             25037..26014
                     /gene="csiD"
                     /locus_tag="ROH59_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311547.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HDX4802580.1"
                     /translation="MNALTAVQNNAVDSGQDYRGFTLIPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFQVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGI
                     DDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNIQGGNSLLLHLDDWEHLDLFFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGTLSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ"
     gene            26034..27299
                     /gene="lhgO"
                     /locus_tag="ROH59_000030"
     CDS             26034..27299
                     /gene="lhgO"
                     /locus_tag="ROH59_000030"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HDX4802581.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDIYPDARIALLEKESGPACHQTG
                     HNSGVIHAGVYYTPGSLKTQFCLAGNRATKVFCDQNGIRYDNCGKMLVATSELEMERM
                     NALWKRTAANGIEREWLNAEELREREPNITGLGGIFVPSSGIVSYREVTAAMAKIFQA
                     RGGEIIYNAEVSALSEHKNGVVIRTRQGGEYEASTLISCSGLMADRLVKMLGLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPWPPGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFN"
     gene            27325..28773
                     /gene="gabD"
                     /locus_tag="ROH59_000031"
     CDS             27325..28773
                     /gene="gabD"
                     /locus_tag="ROH59_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HDX4802582.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPK
                     MGADETRAAIDAASRALPAWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGN
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDSVYDRFAEKLQQAVSKLHIGDGLEKGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIIGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            28787..30067
                     /gene="gabT"
                     /locus_tag="ROH59_000032"
     CDS             28787..30067
                     /gene="gabT"
                     /locus_tag="ROH59_000032"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HDX4802583.1"
                     /translation="MISNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYAAT
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANVLGQKLKDG
                     LLAIAEKHPEIGDVRGLGAMIAIELFEDGDHSKPDAKLTAEIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIISQCFAEAKL"
     gene            30304..31704
                     /gene="gabP"
                     /locus_tag="ROH59_000033"
     CDS             30304..31704
                     /gene="gabP"
                     /locus_tag="ROH59_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HDX4802584.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYADVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTSAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLIMWQKTPIHNTR"
     gene            31725..32387
                     /gene="csiR"
                     /locus_tag="ROH59_000034"
     CDS             31725..32387
                     /gene="csiR"
                     /locus_tag="ROH59_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HDX4802585.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSYYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(32388..32837)
                     /gene="kbp"
                     /locus_tag="ROH59_000035"
     CDS             complement(32388..32837)
                     /gene="kbp"
                     /locus_tag="ROH59_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HDX4802586.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLNKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(32921..33079)
                     /locus_tag="ROH59_000036"
     CDS             complement(32921..33079)
                     /locus_tag="ROH59_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HDX4802587.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
     gene            33262..33561
                     /locus_tag="ROH59_000037"
     CDS             33262..33561
                     /locus_tag="ROH59_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4802588.1"
                     /translation="MTELAQLQASAEQAAALLKSMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRGEGLIDCQRDAQRILYSIKNEAVNAIIATLKNVYCP"
     gene            33571..34095
                     /gene="ygaP"
                     /locus_tag="ROH59_000038"
     CDS             33571..34095
                     /gene="ygaP"
                     /locus_tag="ROH59_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HDX4802589.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPPKLRREQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKKAGLP
                     VAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSVFFLLSGFVGAGLLLAGISGFCG
                     MARLLDKMPWNQRA"
     gene            complement(34142..34546)
                     /gene="stpA"
                     /locus_tag="ROH59_000039"
     CDS             complement(34142..34546)
                     /gene="stpA"
                     /locus_tag="ROH59_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HDX4802590.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFIDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
     gene            35214..35663
                     /gene="alaE"
                     /locus_tag="ROH59_000040"
     CDS             35214..35663
                     /gene="alaE"
                     /locus_tag="ROH59_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HDX4802591.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADILAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
     gene            complement(35700..36044)
                     /locus_tag="ROH59_000041"
     CDS             complement(35700..36044)
                     /locus_tag="ROH59_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HDX4802592.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGEAS"
     gene            36196..36525
                     /locus_tag="ROH59_000042"
     CDS             36196..36525
                     /locus_tag="ROH59_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDX4802593.1"
                     /translation="MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAE
                     AARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGA
                     LLSMRKS"
     gene            36772..37017
                     /gene="nrdH"
                     /locus_tag="ROH59_000043"
     CDS             36772..37017
                     /gene="nrdH"
                     /locus_tag="ROH59_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDX4802594.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            37014..37424
                     /gene="nrdI"
                     /locus_tag="ROH59_000044"
     CDS             37014..37424
                     /gene="nrdI"
                     /locus_tag="ROH59_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDX4802595.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYIL
                     IVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA"
     gene            37397..39541
                     /gene="nrdE"
                     /locus_tag="ROH59_000045"
     CDS             37397..39541
                     /gene="nrdE"
                     /locus_tag="ROH59_000045"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDX4802596.1"
                     /translation="MATTTAERLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAF
                     MTTHVRPNSVAFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHASGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLATQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADVAISERYDEL
                     VADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHALRT
                     SMLLARERGETFAGFKQSRYASGEYFSQYLQSNWQPKTAKVGELFARSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL"
     gene            39551..40510
                     /gene="nrdF"
                     /locus_tag="ROH59_000046"
     CDS             39551..40510
                     /gene="nrdF"
                     /locus_tag="ROH59_000046"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDX4802597.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPDALTPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNLEKISQARREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
     gene            40866..42068
                     /gene="proV"
                     /locus_tag="ROH59_000047"
     CDS             40866..42068
                     /gene="proV"
                     /locus_tag="ROH59_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HDX4802598.1"
                     /translation="MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGV
                     KDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDVELRE
                     VRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS
                     YPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTI
                     VFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSA
                     KDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKAALT
                     QQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRAL
                     DREGVNNG"
     gene            42061..43125
                     /gene="proW"
                     /locus_tag="ROH59_000048"
     CDS             42061..43125
                     /gene="proW"
                     /locus_tag="ROH59_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HDX4802599.1"
                     /translation="MADQNNPWDTTPAADSAAQSADAWGTPAAAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQIPADLIEASRSFGASPSQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            43182..44174
                     /gene="proX"
                     /locus_tag="ROH59_000049"
     CDS             43182..44174
                     /gene="proX"
                     /locus_tag="ROH59_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HDX4802600.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYGLTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNANTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEDDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            44366..45550
                     /locus_tag="ROH59_000050"
     CDS             44366..45550
                     /locus_tag="ROH59_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4802601.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMM
                     ILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISDKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGSWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            45674..46411
                     /gene="ygaZ"
                     /locus_tag="ROH59_000051"
     CDS             45674..46411
                     /gene="ygaZ"
                     /locus_tag="ROH59_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine exporter subunit YgaZ"
                     /protein_id="HDX4802602.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWVAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            46401..46736
                     /gene="ygaH"
                     /locus_tag="ROH59_000052"
     CDS             46401..46736
                     /gene="ygaH"
                     /locus_tag="ROH59_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HDX4802603.1"
                     /translation="MSYEVLLLGLLVGAANYCFRYLPLRLRVGNARPTKRGAVGILLD
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            46827..47357
                     /gene="emrR"
                     /locus_tag="ROH59_000053"
     CDS             46827..47357
                     /gene="emrR"
                     /locus_tag="ROH59_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HDX4802604.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQGGVVLEAMS"
     gene            47484..48656
                     /gene="emrA"
                     /locus_tag="ROH59_000054"
     CDS             47484..48656
                     /gene="emrA"
                     /locus_tag="ROH59_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HDX4802605.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            48673..50211
                     /gene="emrB"
                     /locus_tag="ROH59_000055"
     CDS             48673..50211
                     /gene="emrB"
                     /locus_tag="ROH59_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HDX4802606.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGHETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESLHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            50469..51176
                     /locus_tag="ROH59_000056"
     CDS             50469..51176
                     /locus_tag="ROH59_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase family protein"
                     /protein_id="HDX4802607.1"
                     /translation="MNTQRKYGRTWHYPFSPGTTSDDRINTDYWQDLQTITQLVHTEK
                     LDGENNCLNRYGVFARSHATPTQSAWTYKIRQRWQLLKNDLGNLELFGENLYAVHSIE
                     YRALEQDFYLFAVRCQDMWLSWEEVQFYAALFDFPCVPEISGPQPGNDEKSWQRDFLA
                     LTNARGTFDPWDTQTCQPCTLEGIVSRNHDAFSVADFSHNVFKYVRKNHVKTTVHWKR
                     HWQRARMAHEFVYGEQS"
     gene            51173..52285
                     /locus_tag="ROH59_000057"
     CDS             51173..52285
                     /locus_tag="ROH59_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX4802608.1"
                     /translation="MIWQLTDDKRWSALRQRFSWVEEMHHTPQDPEHHGEGDVGVHTE
                     MVLNALITLPEFQQLPAQQQEVLWAAALLHDVEKRSTTVQENGRIQSPGHARRGELTA
                     RQILWRDIPTPFVLREQIVALVRLHGLPLWLLERPEPERLLLTAAMRIDTRLLALLAR
                     ADLLGRQSPDQQSMLERIDLFELFCHEQQCWGKMRPFVSDSARWHYLTHEQSSPDFVP
                     WEAEPFEVILLCGLPGMGKDRYISEQCQGMDVISLDDMRRRINASPDDKTATGRIVQQ
                     AKEEARVFLRQKKPFIWNATNITRQLRSQLISLFTAYGARVKIVYLEVPWAQWNQQNA
                     RREYAVPEAVVMRMASRLEVPQPDEAHSVEYRMTDR"
     gene            complement(52336..52851)
                     /gene="luxS"
                     /locus_tag="ROH59_000058"
     CDS             complement(52336..52851)
                     /gene="luxS"
                     /locus_tag="ROH59_000058"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDX4802609.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARNILERDVRINSNEELA
                     LPKEKLQELHI"
     gene            complement(53001..54557)
                     /gene="gshA"
                     /locus_tag="ROH59_000059"
     CDS             complement(53001..54557)
                     /gene="gshA"
                     /locus_tag="ROH59_000059"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDX4802610.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTE
                     PFAVWLEKHA"
     gene            complement(54630..55058)
                     /locus_tag="ROH59_000060"
     CDS             complement(54630..55058)
                     /locus_tag="ROH59_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX4802611.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGVSHPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            complement(55055..55621)
                     /gene="yqaB"
                     /locus_tag="ROH59_000061"
     CDS             complement(55055..55621)
                     /gene="yqaB"
                     /locus_tag="ROH59_000061"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HDX4802612.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
                     QCVVFEDADFGIQAARAAGMDAVDVRLL"
     gene            complement(55902..55978)
                     /locus_tag="ROH59_000062"
     tRNA            complement(55902..55978)
                     /locus_tag="ROH59_000062"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55942..55944),aa:Arg,seq:acg)
     gene            complement(56042..56118)
                     /locus_tag="ROH59_000063"
     tRNA            complement(56042..56118)
                     /locus_tag="ROH59_000063"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56082..56084),aa:Arg,seq:acg)
     gene            complement(56181..56257)
                     /locus_tag="ROH59_000064"
     tRNA            complement(56181..56257)
                     /locus_tag="ROH59_000064"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56221..56223),aa:Arg,seq:acg)
     gene            complement(56322..56398)
                     /locus_tag="ROH59_000065"
     tRNA            complement(56322..56398)
                     /locus_tag="ROH59_000065"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56362..56364),aa:Arg,seq:acg)
     gene            complement(56402..56494)
                     /locus_tag="ROH59_000066"
     tRNA            complement(56402..56494)
                     /locus_tag="ROH59_000066"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56458..56460),aa:Ser,seq:gct)
     gene            complement(56810..56995)
                     /gene="csrA"
                     /locus_tag="ROH59_000067"
     CDS             complement(56810..56995)
                     /gene="csrA"
                     /locus_tag="ROH59_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDX4802613.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(57230..59860)
                     /gene="alaS"
                     /locus_tag="ROH59_000068"
     CDS             complement(57230..59860)
                     /gene="alaS"
                     /locus_tag="ROH59_000068"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDX4802614.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFDAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKSVDAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLAVGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(59989..60489)
                     /gene="recX"
                     /locus_tag="ROH59_000069"
     CDS             complement(59989..60489)
                     /gene="recX"
                     /locus_tag="ROH59_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDX4802615.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARICQELNQKGIS
                     REATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDI
                     WRNFAD"
     gene            complement(60558..61619)
                     /gene="recA"
                     /locus_tag="ROH59_000070"
     CDS             complement(60558..61619)
                     /gene="recA"
                     /locus_tag="ROH59_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDX4802616.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(61699..62196)
                     /gene="pncC"
                     /locus_tag="ROH59_000071"
     CDS             complement(61699..62196)
                     /gene="pncC"
                     /locus_tag="ROH59_000071"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HDX4802617.1"
                     /translation="MTESELMQLSEQVGLALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            62378..62617
                     /locus_tag="ROH59_000072"
     CDS             62378..62617
                     /locus_tag="ROH59_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802618.1"
                     /translation="MAIKKTDNTPQNVLKQTTQMRMWVIIGGISALISVICKVLSSGY
                     LEPFDFGQAALGVVCLGYAISLSKKIKQLRHSNKQ"
     gene            complement(62656..63741)
                     /gene="mltB"
                     /locus_tag="ROH59_000073"
     CDS             complement(62656..63741)
                     /gene="mltB"
                     /locus_tag="ROH59_000073"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HDX4802619.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETETTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTRYSISQLAAAGLTPQQSLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALARVQ"
     gene            63998..64561
                     /gene="srlA"
                     /locus_tag="ROH59_000074"
                     /gene_synonym="gutA"
     CDS             63998..64561
                     /gene="srlA"
                     /locus_tag="ROH59_000074"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDX4802620.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVRLAGATS"
     gene            64558..65517
                     /gene="srlE"
                     /locus_tag="ROH59_000075"
                     /gene_synonym="gutE"
     CDS             64558..65517
                     /gene="srlE"
                     /locus_tag="ROH59_000075"
                     /gene_synonym="gutE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDX4802621.1"
                     /translation="MTRIRIEKGTGGWGGPLELEATPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITVVGEATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSAVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            65528..65899
                     /gene="srlB"
                     /locus_tag="ROH59_000076"
                     /gene_synonym="gutB"
     CDS             65528..65899
                     /gene="srlB"
                     /locus_tag="ROH59_000076"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDX4802622.1"
                     /translation="MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGALHPGLQFTLGRHRYPVTAVGSVAEDNLRELGHVTLRFDGLSEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            65903..66682
                     /gene="srlD"
                     /locus_tag="ROH59_000077"
     CDS             65903..66682
                     /gene="srlD"
                     /locus_tag="ROH59_000077"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDX4802623.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGEGTAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPEQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            66788..67147
                     /gene="gutM"
                     /locus_tag="ROH59_000078"
     CDS             66788..67147
                     /gene="gutM"
                     /locus_tag="ROH59_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDX4802624.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPH
                     DPLSQNALSLALKLKRG"
     gene            67214..67987
                     /gene="srlR"
                     /locus_tag="ROH59_000079"
                     /gene_synonym="gutR"
     CDS             67214..67987
                     /gene="srlR"
                     /locus_tag="ROH59_000079"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HDX4802625.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVGFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEEKGIDVIITGESNE"
     gene            67980..68945
                     /gene="gutQ"
                     /locus_tag="ROH59_000080"
     CDS             67980..68945
                     /gene="gutQ"
                     /locus_tag="ROH59_000080"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HDX4802626.1"
                     /translation="MSEALLNAGRQTLMLELQEASHLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASV
                     MDAMLELSRTGLGLVAVCDDQRLVKGVFTDGDLRRWLVGGGALTTPVNEAMTVDGTTL
                     QSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(68942..70456)
                     /gene="norR"
                     /locus_tag="ROH59_000081"
     CDS             complement(68942..70456)
                     /gene="norR"
                     /locus_tag="ROH59_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HDX4802627.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGAR
                     NLLQHYNFPGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVP
                     VVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD"
     gene            70643..72082
                     /gene="norV"
                     /locus_tag="ROH59_000082"
     CDS             70643..72082
                     /gene="norV"
                     /locus_tag="ROH59_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HDX4802628.1"
                     /translation="MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     AETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREI
                     ARQWALAPLPQSTVNTVVKEETSAATTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGT
                     PWSEVPDNFLCPECSLGKDVFDELASEAK"
     gene            72079..73212
                     /gene="norW"
                     /locus_tag="ROH59_000083"
     CDS             72079..73212
                     /gene="norW"
                     /locus_tag="ROH59_000083"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HDX4802629.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDACIPLTLIAADSMDEYNKP
                     DLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILA
                     TLDRQRCIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGEPQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLSM"
     gene            complement(73434..75686)
                     /gene="hypF"
                     /locus_tag="ROH59_000084"
     CDS             complement(73434..75686)
                     /gene="hypF"
                     /locus_tag="ROH59_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HDX4802630.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLLEEPETFLVQLHQHCPPLARIDSVEREPFIWSQLPTEFTIRQSTGGAMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ACDKEYCDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGNIVAI
                     KGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISN
                     EQALADLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVP
                     PVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDAHPGYVSSQWAREMNLPTQTVLHHHAHAAACLAEHHWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALAGGDLAAKQPWRNLLTQCLRFVPEWQSYPE
                     TVSVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
                     LATSCHGVTHPVTMPLVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGGAALMRE
                     QATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RWLAGEVQNG"
     gene            complement(75839..76366)
                     /gene="hydN"
                     /locus_tag="ROH59_000085"
     CDS             complement(75839..76366)
                     /gene="hydN"
                     /locus_tag="ROH59_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HDX4802631.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
     gene            76794..77231
                     /locus_tag="ROH59_000086"
     CDS             76794..77231
                     /locus_tag="ROH59_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802632.1"
                     /translation="MGSWGMEALESDEGLDLINWVEEQLQDDSTFDAESIVQRLSQHE
                     DLFGFQGDEEFLYDNYDNNVIGLVELIIQKAAGKKITSSKQIDQLDGYQLTSTFSKKL
                     QGRLQTIDDTHEWIMLFEGRAREKAKAYLIELTDKLRVVKTTA"
     gene            complement(77323..77742)
                     /locus_tag="ROH59_000087"
     CDS             complement(77323..77742)
                     /locus_tag="ROH59_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4802633.1"
                     /translation="MTANAARAVKATRELVNAVPFLGGSDSEDDYREALELVEYLIEE
                     DDTNPLIDFLASRIAEYENNNEKFAEFDKAVAAMPVGVALLRTLIDQHNLTYADLKNE
                     IGSKSLVSQILSGQRSLTISHIKALSARFGVKPEWFL"
     gene            complement(77768..77953)
                     /locus_tag="ROH59_000088"
     CDS             complement(77768..77953)
                     /locus_tag="ROH59_000088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802634.1"
                     /translation="MNIKTGMCAFLLSLVLPAQATSFTEYLPMSDSEYAQKRALKPLL
                     TMPYDAEQTWHFRKVGV"
     gene            complement(77978..78445)
                     /gene="hycI"
                     /locus_tag="ROH59_000089"
     CDS             complement(77978..78445)
                     /gene="hycI"
                     /locus_tag="ROH59_000089"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HDX4802635.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPADIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEE"
     gene            complement(78438..78848)
                     /gene="hycH"
                     /locus_tag="ROH59_000090"
     CDS             complement(78438..78848)
                     /gene="hycH"
                     /locus_tag="ROH59_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase assembly protein HycH"
                     /protein_id="HDX4802636.1"
                     /translation="MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDDYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARAA
                     QTSQQKEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            complement(78845..79612)
                     /gene="hycG"
                     /locus_tag="ROH59_000091"
     CDS             complement(78845..79612)
                     /gene="hycG"
                     /locus_tag="ROH59_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HDX4802637.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGEQDEQPADILHPDMVQPLRVKVDREARRLAGYRYGRQIADDFLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            complement(79612..80154)
                     /gene="hycF"
                     /locus_tag="ROH59_000092"
     CDS             complement(79612..80154)
                     /gene="hycF"
                     /locus_tag="ROH59_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HDX4802638.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWQFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            complement(80164..81873)
                     /gene="hycE"
                     /locus_tag="ROH59_000093"
     CDS             complement(80164..81873)
                     /gene="hycE"
                     /locus_tag="ROH59_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HDX4802639.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWVTVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(81891..82814)
                     /gene="hycD"
                     /locus_tag="ROH59_000094"
     CDS             complement(81891..82814)
                     /gene="hycD"
                     /locus_tag="ROH59_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HDX4802640.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTVGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITPRITWAGFGFAFLAFVSLLAA"
     gene            complement(82817..84643)
                     /gene="hycC"
                     /locus_tag="ROH59_000095"
     CDS             complement(82817..84643)
                     /gene="hycC"
                     /locus_tag="ROH59_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HDX4802641.1"
                     /translation="MSAISLINSGVAWFVAAAVLAFLFSFQKALSGWIAGIGGAVGSL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFVSLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEIMALCAVFLTSNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCSPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            complement(84640..85251)
                     /gene="hycB"
                     /locus_tag="ROH59_000096"
     CDS             complement(84640..85251)
                     /gene="hycB"
                     /locus_tag="ROH59_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HDX4802642.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCATVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANTNTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            complement(85376..85837)
                     /gene="hycA"
                     /locus_tag="ROH59_000097"
     CDS             complement(85376..85837)
                     /gene="hycA"
                     /locus_tag="ROH59_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HDX4802643.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPVA"
     gene            86049..86399
                     /gene="hypA"
                     /locus_tag="ROH59_000098"
     CDS             86049..86399
                     /gene="hypA"
                     /locus_tag="ROH59_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDX4802644.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            86403..87275
                     /gene="hypB"
                     /locus_tag="ROH59_000099"
     CDS             86403..87275
                     /gene="hypB"
                     /locus_tag="ROH59_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HDX4802645.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     APEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     MDQWLNWLETQRCA"
     gene            87266..87538
                     /gene="hypC"
                     /locus_tag="ROH59_000100"
     CDS             87266..87538
                     /gene="hypC"
                     /locus_tag="ROH59_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HDX4802646.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            87538..88659
                     /gene="hypD"
                     /locus_tag="ROH59_000101"
     CDS             87538..88659
                     /gene="hypD"
                     /locus_tag="ROH59_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HDX4802647.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA"
     gene            88656..89666
                     /gene="hypE"
                     /locus_tag="ROH59_000102"
     CDS             88656..89666
                     /gene="hypE"
                     /locus_tag="ROH59_000102"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HDX4802648.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLAPLIQTLRDIPGVKA
                     LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            89740..91818
                     /gene="flhA"
                     /locus_tag="ROH59_000103"
     CDS             89740..91818
                     /gene="flhA"
                     /locus_tag="ROH59_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HDX4802649.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRSILSRPDTLHCSYEEFC
                     ETWPQLATGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFNTWGNQIQTLCLLPLMSGDTMLGVLKLAQCEEKVFTTTNLNLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRILSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     ALPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            91863..92291
                     /locus_tag="ROH59_000104"
     CDS             91863..92291
                     /locus_tag="ROH59_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012134844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
                     /protein_id="HDX4802650.1"
                     /translation="MAVSARNQLTGTVSAVAMGAVNDEVELTLAGGAKLVAIVTHSSQ
                     QALGLAKGKEAIALIKAPWVTLATEDCGLKFSARNQFAGSVSTITEGAVNATVHIKTD
                     AGFEIVAVVTNESQDEMKLTTGSRVIALIKASAILIATKA"
     gene            complement(92330..92674)
                     /locus_tag="ROH59_000105"
     CDS             complement(92330..92674)
                     /locus_tag="ROH59_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HDX4802651.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYEALFAYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKK"
     gene            92960..95521
                     /gene="mutS"
                     /locus_tag="ROH59_000106"
     CDS             92960..95521
                     /gene="mutS"
                     /locus_tag="ROH59_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDX4802652.1"
                     /translation="MSTIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMERQQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLENVDSAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERL
                     EVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            95627..96283
                     /gene="pphB"
                     /locus_tag="ROH59_000107"
     CDS             95627..96283
                     /gene="pphB"
                     /locus_tag="ROH59_000107"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDX4802653.1"
                     /translation="MPSTRYQKINAHHYRHIWAVGDIHGDYQLLQSRLHQLSFCPETD
                     LLISVGDNIDRGPESLNVLRLLNQPWFISVKGNHEAMALEAFETGDGNMWLASGGDWF
                     FDLNDSEQQEAIDLLLKFHLLPHIIEITNDNIKYVIAHADYPGKEYQFGKEIAESELL
                     WPVDRVQKSLNSELQKINGADFFIFGHMMFDNIQTFANQIYIDTGSPKSGRLSFYKIK
                     "
     gene            complement(96334..97101)
                     /locus_tag="ROH59_000108"
     CDS             complement(96334..97101)
                     /locus_tag="ROH59_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4802654.1"
                     /translation="MIPVERRQIILEMVAEKGIVSIAELTDRMNVSHMTIRRDLQKLE
                     QQGAVVLVSGGVQSPGRVAHEPSHQVKTALAMTQKAAIGKLAASLVQPGRCIYLDAGT
                     TTLAIAQHLIHMEPLTVVTNDFVIADYLLDNSNCTIIHTGGAVCRENRSCVGEAAATM
                     LRSLMIDQAFISASSWSVRGISTPAEDKVTVKRAIASASRQRVLVCDATKYGQVATWL
                     ALPLSEFDQIITDDGLPESASRALAKLDLSLLVAKNE"
     gene            97297..98205
                     /locus_tag="ROH59_000109"
     CDS             97297..98205
                     /locus_tag="ROH59_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDX4802655.1"
                     /translation="MKTGSEFHVGIVGLGSMGMGAALSCVRAGLSTWGADLNSNACAT
                     LKEAGACGVSDNAATFAEKLDALLVLVVNATQVKQVLFGEKGVAQHLKPGTAVMVSST
                     IANADAQEIATALAGFGLEMLDAPVSGGAVKAANGEMTVMASGSDIAFERLAPVLEAV
                     AGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAG
                     NSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSAS
                     NAGYGKEDDSAVIKIFSGITLPGAKS"
     gene            98202..99464
                     /locus_tag="ROH59_000110"
     CDS             98202..99464
                     /locus_tag="ROH59_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxo-tetronate kinase"
                     /protein_id="HDX4802656.1"
                     /translation="MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAID
                     ALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDAL
                     MDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEA
                     QSTGRCGVVSAHVFEQGVKAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPL
                     VTGGSGLAIGLARQWAQENGNQAREAGRPLAGRGVVLSGSCSQMTNRQVAHYRQIAPA
                     REVDVARCLSTETLAAYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAQKAS
                     QAVETLFSQLAARLAAEGVTRFIVAGGETSGVVTQSLGIKGFHIGPTISPGVPWVNAL
                     DKPVSLALKSGNFGDEAFFSRAQREFLS"
     gene            99461..100099
                     /locus_tag="ROH59_000111"
     CDS             99461..100099
                     /locus_tag="ROH59_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDX4802657.1"
                     /translation="MSDFAKVEQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNL
                     LATPTGSCLGNLDPQRLSKVTADGEWLSGDNPSKEVLFHLALYRNNPLCKAVVHLHST
                     WSTALSCLEGLDSNNVIRPFTPYVVMRMGNVPLVPYYRPGDKRIAQDLAELAADNQAF
                     LLANHGPVVCGESLQEAANNMEELEETAKLIFILGDRPIRYLTAGEIAELRS"
     gene            100104..100880
                     /locus_tag="ROH59_000112"
     CDS             100104..100880
                     /locus_tag="ROH59_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDX4802658.1"
                     /translation="MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYDYSPQQ
                     IQQQLVQNHLTLALFNTAPGDINAGEWGLSALPGREHEARADIDLALEYALALNCEQV
                     HVMAGVVPAGEDAERYRAVFIDNLRYAADRFAPHGKRILVEALSPGVKPHYLFSSQYQ
                     ALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRNYAGKYAHVQIAGLPDRHEPDDGE
                     INYPWLFRLFDEVGYQGWIGCEYKPRGLTKEGLGWFDAWR"
     gene            100969..102333
                     /locus_tag="ROH59_000113"
     CDS             100969..102333
                     /locus_tag="ROH59_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family transporter"
                     /protein_id="HDX4802659.1"
                     /translation="MSTITLLCIALAGVIMLLLLVIKAKVQPFVALLLVSLLVALAAG
                     IPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTI
                     AALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPP
                     HPGPVAAAGLLHADIGWLTIIGIAISIPVGIVGYFAAKIINKRQYAMSVEVLEQMQLA
                     PASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGS
                     PMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVES
                     GVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQC
                     VLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCV
                     WLVI"
     gene            complement(102476..103519)
                     /locus_tag="ROH59_000114"
     CDS             complement(102476..103519)
                     /locus_tag="ROH59_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDX4802660.1"
                     /translation="MQGIKIYTILASSLISGSVFAQTEISTSNSSTVNASYVEPSAEK
                     IISPSDKLNNLFERNMSQPYILQKIGERTYYVQRYFYSTTFYVGDKGVLLFDAPEGRG
                     KYLLQAIRDVTPLPVTALVYSHYHVDHIGDSPFWNDEAKKEGVNLRIIASKATAEKMQ
                     FMNSRLPVATQVLSKKDDQFKFEKQTIELHRFVKAGHTDDHSVWLLKQEKVAHSPDLL
                     NPDQLPMMGFAVSDTLVYHDSNLRQVEMLDWKYFIGGHGNIGSHDDFKFQRQFLNDLR
                     DTTIKVRKEESFGKFMNKTANNHADFARAQREAIIKKVTEVLRPKYGHMYGYDASMPA
                     NIEMAIRLVGSYY"
     gene            103744..104295
                     /locus_tag="ROH59_000115"
     CDS             103744..104295
                     /locus_tag="ROH59_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDX4802661.1"
                     /translation="MQNIAVVYYSGYGHTKLVAEKVAQGAHADLISIDNEGNITEQEW
                     EKLDAADAIIFGAPTYMGGAPWQFKKFADASSKAWFTRKWQDKVFGGFTNSASLNGDK
                     QVTLIYLQTLASQHGGLWVSLGQAPANVLASTREDVNNLGGSVGLLVQSPADAGAEQI
                     PTGDLDTAVKYGERVATITARLK"
     gene            complement(104466..105458)
                     /gene="rpoS"
                     /locus_tag="ROH59_000116"
     CDS             complement(104466..105458)
                     /gene="rpoS"
                     /locus_tag="ROH59_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HDX4802662.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(105521..106660)
                     /gene="nlpD"
                     /locus_tag="ROH59_000117"
     CDS             complement(105521..106660)
                     /gene="nlpD"
                     /locus_tag="ROH59_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HDX4802663.1"
                     /translation="MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAP
                     ANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENG
                     RIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
                     QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSA
                     NKMLPNNKPTATTVTVPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASE
                     GGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLV
                     REQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(106800..107426)
                     /gene="pcm"
                     /locus_tag="ROH59_000118"
     CDS             complement(106800..107426)
                     /gene="pcm"
                     /locus_tag="ROH59_000118"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HDX4802664.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(107420..108181)
                     /gene="surE"
                     /locus_tag="ROH59_000119"
     CDS             complement(107420..108181)
                     /gene="surE"
                     /locus_tag="ROH59_000119"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HDX4802665.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            complement(108162..109211)
                     /gene="truD"
                     /locus_tag="ROH59_000120"
     CDS             complement(108162..109211)
                     /gene="truD"
                     /locus_tag="ROH59_000120"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HDX4802666.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALLGSGEWGTQREALAFEQ
                     AAVAEETELQTLLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            complement(109208..109687)
                     /gene="ispF"
                     /locus_tag="ROH59_000121"
     CDS             complement(109208..109687)
                     /gene="ispF"
                     /locus_tag="ROH59_000121"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDX4802667.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            complement(109687..110397)
                     /gene="ispD"
                     /locus_tag="ROH59_000122"
     CDS             complement(109687..110397)
                     /gene="ispD"
                     /locus_tag="ROH59_000122"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDX4802668.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKRVVIAISPGDSRFAQLPLANHPRITVVDGGEERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            complement(110416..110727)
                     /gene="ftsB"
                     /locus_tag="ROH59_000123"
     CDS             complement(110416..110727)
                     /gene="ftsB"
                     /locus_tag="ROH59_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HDX4802669.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNNDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            complement(110920..111243)
                     /locus_tag="ROH59_000124"
     CDS             complement(110920..111243)
                     /locus_tag="ROH59_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HDX4802670.1"
                     /translation="MRNSHNITLTNNDSLTEVEDTTWSLPGAVVGFLSWLCALAIPML
                     IYGSNTLLFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLATVGIMFGALF
                     MWLLG"
     gene            complement(111292..111897)
                     /gene="cysC"
                     /locus_tag="ROH59_000125"
     CDS             complement(111292..111897)
                     /gene="cysC"
                     /locus_tag="ROH59_000125"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HDX4802671.1"
                     /translation="MALHDENVVWHSHPVTLQQREQHHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            complement(111897..113324)
                     /gene="cysN"
                     /locus_tag="ROH59_000126"
     CDS             complement(111897..113324)
                     /gene="cysN"
                     /locus_tag="ROH59_000126"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HDX4802672.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEVLPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSA
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            complement(113326..114234)
                     /gene="cysD"
                     /locus_tag="ROH59_000127"
     CDS             complement(113326..114234)
                     /gene="cysD"
                     /locus_tag="ROH59_000127"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HDX4802673.1"
                     /translation="MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            114486..115523
                     /gene="iap"
                     /locus_tag="ROH59_000128"
     CDS             114486..115523
                     /gene="iap"
                     /locus_tag="ROH59_000128"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HDX4802674.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIA
                     AHEGKTPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSV
                     EATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIM
                     LPLVKELAKAS"
     gene            complement(115649..115801)
                     /locus_tag="ROH59_000129"
     CDS             complement(115649..115801)
                     /locus_tag="ROH59_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDX4802675.1"
                     /translation="MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVL
                     AYESKK"
     gene            complement(116067..116801)
                     /gene="cysH"
                     /locus_tag="ROH59_000130"
     CDS             complement(116067..116801)
                     /gene="cysH"
                     /locus_tag="ROH59_000130"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDX4802676.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMAEEETRFFGLKRECGLHEG"
     gene            complement(116875..118587)
                     /gene="cysI"
                     /locus_tag="ROH59_000131"
     CDS             complement(116875..118587)
                     /gene="cysI"
                     /locus_tag="ROH59_000131"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HDX4802677.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            complement(118587..120386)
                     /gene="cysJ"
                     /locus_tag="ROH59_000132"
     CDS             complement(118587..120386)
                     /gene="cysJ"
                     /locus_tag="ROH59_000132"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HDX4802678.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSV
                     ATGTVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSDLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIAS
                     SQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPTN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GVLTRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            120705..121067
                     /gene="queD"
                     /locus_tag="ROH59_000133"
     CDS             120705..121067
                     /gene="queD"
                     /locus_tag="ROH59_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HDX4802679.1"
                     /translation="MSTTLFKDFTFEAAHRLPHVPQGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCIYRGE"
     gene            121145..122416
                     /locus_tag="ROH59_000134"
     CDS             121145..122416
                     /locus_tag="ROH59_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417246.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDX4802680.1"
                     /translation="MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNL
                     SGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRA
                     RFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILHARYVVLAEGANSVL
                     AERHGLVTRPAGEAMALGIKEVLTLEPSAIEERFHLENNEGAALLFSGGICDDLPGGA
                     FLYTNQQTLSLGIVCPLSSLTQSSVPASELLTRFKTHPAVRPLIKNTELLEYGAHLVP
                     EGGLRSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHRE
                     PQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRVWPGLMQDISRDLWDQGNTP
                     VPPLRQLLWRHLRRHGLWHLTGDVIRSLRCL"
     gene            122407..122667
                     /locus_tag="ROH59_000135"
     CDS             122407..122667
                     /locus_tag="ROH59_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311649.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HDX4802681.1"
                     /translation="MSVARNLWRAADAPHIVPTDSVERQTAQRLINACPAGLFSLTPE
                     GGLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG"
     gene            122684..123259
                     /locus_tag="ROH59_000136"
     CDS             122684..123259
                     /locus_tag="ROH59_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HDX4802682.1"
                     /translation="MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTIS
                     NIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGF
                     FCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVC
                     DEEDARNAINAGVVALSTTNTGVWTLAKKLL"
     gene            complement(123407..124267)
                     /locus_tag="ROH59_000137"
     CDS             complement(123407..124267)
                     /locus_tag="ROH59_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417249.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDX4802683.1"
                     /translation="MNIVIVTINQDHAAIASWLAAQDFSGCTLAHWQIEPQPMVAEQV
                     LDALVEQWQRTPADVVLFPPGAFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHW
                     GNALTATLQTDKRPLCLSLARQAGADKNATLPSGMQQLNIVPGVLPDWLVSIENLKNV
                     IRDPLAEARRVLVVGQGGEADNQEIAMLAEKMGAEVGYSRARVMNGGVDAEKVIGISG
                     HLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEA
                     LVTNIHADCQ"
     gene            complement(124264..125043)
                     /locus_tag="ROH59_000138"
     CDS             complement(124264..125043)
                     /locus_tag="ROH59_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDX4802684.1"
                     /translation="MNILLAFKAEPDAGMLAEKEWQAAAQGNSGPDVSLLRSLLGADE
                     QAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPE
                     FVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLVWPCFTQVERFTLDAPFI
                     TLEQRTEHGVRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAAIIRKTVAVELPA
                     MQCLQLARAEQRRGATLIGGQTVAEKAQKLWQDYLRQRMQP"
     gene            complement(125021..126430)
                     /locus_tag="ROH59_000139"
     CDS             complement(125021..126430)
                     /locus_tag="ROH59_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4802685.1"
                     /translation="MTVRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRI
                     AALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWIS
                     DHIGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFS
                     PRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLASAALPALLITLLRWG
                     TPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLFSSRYWRRTAFN
                     SVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHR
                     KFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIR
                     SLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLWAPETKA
                     LPLVAAGNVGGANEHSVSV"
     gene            complement(126452..127906)
                     /locus_tag="ROH59_000140"
     CDS             complement(126452..127906)
                     /locus_tag="ROH59_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDX4802686.1"
                     /translation="MSLSRVAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHG
                     IYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDG
                     SAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
                     IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKKVPRRAAGPDIRHIIIGNEGALCYITE
                     VTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHF
                     ADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVA
                     AERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQ
                     NGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWS
                     KLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK"
     gene            complement(127976..128761)
                     /locus_tag="ROH59_000141"
     CDS             complement(127976..128761)
                     /locus_tag="ROH59_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4802687.1"
                     /translation="MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGAN
                     VFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNA
                     GICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
                     QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVL
                     DHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR"
     gene            129080..130357
                     /locus_tag="ROH59_000142"
     CDS             129080..130357
                     /locus_tag="ROH59_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4802688.1"
                     /translation="MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSN
                     TEIGLIMSTFGIAAIIFYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVML
                     CIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFS
                     RFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVL
                     RISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPL
                     GGIITTYSKVKSPTRVVQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYAS
                     RGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGYWQDTLPAAEAYRNMWL
                     MGMAALGMVIIFTFLLFQKIRTADSAPAMASSK"
     gene            130384..131862
                     /locus_tag="ROH59_000143"
     CDS             130384..131862
                     /locus_tag="ROH59_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX4802689.1"
                     /translation="MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDAD
                     TAEHPDDDLWASLCFASHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLIS
                     WQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSED
                     ATVMEKFNIPRQMLFDVQMPGTILGHITPQAALATHFPAGLPVVCTTSDKPVEALGAG
                     LLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSW
                     LRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMI
                     GFDSSMDYAWIYRSILESVALTLKNNYDNMCHEMNHFAKHVIITGGGSNSDLFMQIFA
                     DVFNLPARRNAINGCASLGAAINTAVGLGLYPDYTTAVDKMVRVKDIFIPIESNAKRY
                     DAMNKGIFKDLTKHTDVILKKSYEVMHGELGNADSIQSWSNA"
     gene            132027..132947
                     /locus_tag="ROH59_000144"
     CDS             132027..132947
                     /locus_tag="ROH59_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001461526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HDX4802690.1"
                     /translation="MSTRVWVLGDAVVDLLPESQGRLLQCPGGAPANVAVGIARLGGK
                     SAFIGKVGDDPFGRFMYQTLSTENVDTRYMSLDPQHRTSIVAVGLDEQGERNFTFMVR
                     PSADLFLQPDDLPAFGPGEWLHLCSIALSAEPSRSTAFLAMEKIRQAGGNISFDPNIR
                     SDLWQSEALLRKYLDRALSLANIAKLSEEELLFISDESQVQQGAYSLVQRYPLTLLLI
                     TQGKNGVLVYFQGQFIHYPAKPVSVVDTTGAGDAFVAGLLAGLADSGIPTNTRQLERI
                     IAQAQICGALATTAKGAMTALPRQHDLPSQ"
     gene            133115..134632
                     /locus_tag="ROH59_000145"
     CDS             133115..134632
                     /locus_tag="ROH59_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003857084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HDX4802691.1"
                     /translation="MYKKTTLAVLIALLTGATTVHAQTDISSIESRLAALEQRLKNAE
                     SRAQAAEARAKTAELQVQKLAETQQQNQLTTQEVAQRTVQLEQKSAENSGFEFHGYAR
                     SGLLMNDAASSSKSGPYLTPAGETGGAVGRLGNEADTYVELNVEHKQTLDNGATTRFK
                     AMLADGQRDYNDWTGGSSNLNIRQAFAELGALPSFTGAFKDSTVWAGKRFDRDNFDIH
                     WLDSDVVFLAGTGGGIYDVKWNETFRSNFSLYGRNFGDLDDIDNNVQNYILTMNHYAG
                     PFQLMVSGLRAKDNDDRKDANGDLIQTDAANTGVHALVGLHNDTFYGLREGTAKTALL
                     YGHGLGAEVKGIGSDGALLSEANTWRFASYGTTPLGSGWYVAPAILAQSSKDRYVKGD
                     SYEWVTFNTRLIKEVTQNFALAFEGSYQYMDLKPKGYQNHNAVNGSFYKLTFAPTLKA
                     NDINNFFSRPELRLFATWMDWSSKLDDFASNDAFGSSGFNTGGEWNFGVQMETWF"
     gene            134693..136063
                     /locus_tag="ROH59_000146"
     CDS             134693..136063
                     /locus_tag="ROH59_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sucrose transporter subunit IIBC"
                     /protein_id="HDX4802692.1"
                     /translation="MDFDKIAQSLLPLLGGKENIASAAHCATRLRLVLVDDTLADQHA
                     IGQIDGVKGCFRNSGQMQIIFGTGVVNKVYAAFIQVAGISESSKADTARLAAQKLNPF
                     QRIARLLSNIFVPIIPAIVASGLLMGLLGMVKTYGWVNADNAIYILLDMCSSAAFIIL
                     PILIGFTAAREFGGNPYLGATLGGILTHPALTNAWGVAAGFQTMNFFGFEIAMIGYQG
                     TVFPVLLAVWFMSIVEKQLRRFIPDALDLILTPFLTVVISGFIALLIIGPAGRALGDG
                     ISFVLSTLIAHAGWLAGLLFGGLYSAIVITGIHHSFHAIEAGLLGNPAIGVNFLLPIW
                     AMANVAQGGACLAVWFKTKDTKIKAITLPSAFSAMLGITEAAIFGINLRFVKPFIAAL
                     IGGAAGGAWVVSVHVYMTAVGLTAIPGMAIVQPTSLVNYIIGMVIAFAVAFSLSLLLK
                     YKTDEE"
     gene            136063..137472
                     /locus_tag="ROH59_000147"
     CDS             136063..137472
                     /locus_tag="ROH59_000147"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001466359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDX4802693.1"
                     /translation="MSMPSQMPAILQAVMKGQSKALADAHYPCWHLAPVTGLMNDPNG
                     FCWSGGRYHLFYQWNPLACDHKYKCWGHWSSTDLLHWQHEPLALMPDKEYDRNGCYSG
                     SAVNNQGVLTLCYTGNVKFDDGSRTAWQCLATENNQGGFDKLGPVIPLPDGYTGHVRD
                     PKVWKHNSQWYMVLGAQDKEKRGKVLLYSSVDLYTWSFHGEIAGNGLNEIDNAGYMWE
                     CPDLFALDGEYILLCCPQGMAREHERYLNTYPCAWLHGQFDYETGKFTHGAFSELDAG
                     FEFYAPQTMEAPDGRRLLVGWMGVPDGEEMLQPTRKHHWQHQMTCFRELSFQKGKLFQ
                     MPIRELAQLREAEHFWQGKADHAPHVEIERLEMDIIPSGELYLNFGNALALHLNDDGI
                     QLQRRSLAGQEKLTRYWRGSVTSLKILCDSSSVEIFINNGEGVMSNRYFPHHPASLIL
                     QGESDVTLRYWSLRACMVE"
     gene            137498..138505
                     /locus_tag="ROH59_000148"
     CDS             137498..138505
                     /locus_tag="ROH59_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX4802694.1"
                     /translation="MRKTKRVTIKDIAELAGVSKATASLVLNGRGKELRVAQETRERV
                     LSIAQQQHYQPSIHARSLRDNRSHTIGLVVPEITNYGFAVFSHELETLCREAGVQLLI
                     SCTDENPSQETMVVNNMIARQVDGLIVASSMLHDNDYQKLSEQLPVVLFDRHMNGSTL
                     PLVITDSVSPTAALVADIARSHPDEFYFLGGQPRLSPTRDRLEGFTQGLQQAGVTLQP
                     EWIIHGNYHPSSGYEMFAALCARLGRPPKALFTAACGLLEGVLRYMSQYNLLDSKIHL
                     ASFDDHYLYDSLSVRIDTIQQDNRQLAFHCFELISQLIEGETPSPLQRYLPASLQKRY
                     R"
     gene            complement(138590..139261)
                     /gene="queE"
                     /locus_tag="ROH59_000149"
     CDS             complement(138590..139261)
                     /gene="queE"
                     /locus_tag="ROH59_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HDX4802695.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKEDATRLCIDTCIARNWRLSMQTHK
                     YLNIA"
     gene            139400..139541
                     /locus_tag="ROH59_000150"
                     /pseudo
     CDS             139400..139541
                     /locus_tag="ROH59_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791252.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            139555..140427
                     /locus_tag="ROH59_000151"
     CDS             139555..140427
                     /locus_tag="ROH59_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HDX4802696.1"
                     /translation="MRYFILIFTLVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKEL
                     TRKLESIFNNTQVQIAVLIIPTTKDETIEQYAARVFDNWRLGDAKRNDGILIIVAWSD
                     RTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQQLAKGLELAIIALNNRLTSQHQY
                     SVNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDL
                     FLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKKASGRSYHSDNSGSGGGSSGGGFSG
                     GGGSSGGGGASGRW"
     gene            complement(140487..141785)
                     /gene="eno"
                     /locus_tag="ROH59_000152"
     CDS             complement(140487..141785)
                     /gene="eno"
                     /locus_tag="ROH59_000152"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDX4802697.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(141873..143510)
                     /gene="pyrG"
                     /locus_tag="ROH59_000153"
     CDS             complement(141873..143510)
                     /gene="pyrG"
                     /locus_tag="ROH59_000153"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HDX4802698.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            complement(143738..144529)
                     /gene="mazG"
                     /locus_tag="ROH59_000154"
     CDS             complement(143738..144529)
                     /gene="mazG"
                     /locus_tag="ROH59_000154"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDX4802699.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQIAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            complement(144625..146859)
                     /gene="relA"
                     /locus_tag="ROH59_000155"
     CDS             complement(144625..146859)
                     /gene="relA"
                     /locus_tag="ROH59_000155"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP diphosphokinase"
                     /protein_id="HDX4802700.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYPPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            complement(146907..148208)
                     /gene="rlmD"
                     /locus_tag="ROH59_000156"
     CDS             complement(146907..148208)
                     /gene="rlmD"
                     /locus_tag="ROH59_000156"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDX4802701.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGL
                     LPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILVPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LECFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVEPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQ
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            148265..151021
                     /gene="barA"
                     /locus_tag="ROH59_000157"
     CDS             148265..151021
                     /gene="barA"
                     /locus_tag="ROH59_000157"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HDX4802702.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSLPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFYHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            complement(151252..152592)
                     /gene="gudD"
                     /locus_tag="ROH59_000158"
     CDS             complement(151252..152592)
                     /gene="gudD"
                     /locus_tag="ROH59_000158"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HDX4802703.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKAT
                     PLPYQSQPDDQCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGTYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPLEIKGGLVQV
                     PEKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(152613..153953)
                     /locus_tag="ROH59_000159"
     CDS             complement(152613..153953)
                     /locus_tag="ROH59_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HDX4802704.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGIGEAPGGEVIYQTLVGAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGQALNVPVCELLGPGKQRDAITVLGYLFYIGDRTKTD
                     LPYLENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            complement(153955..155307)
                     /gene="gudP"
                     /locus_tag="ROH59_000160"
     CDS             complement(153955..155307)
                     /gene="gudP"
                     /locus_tag="ROH59_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HDX4802705.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            complement(155741..156190)
                     /locus_tag="ROH59_000161"
     CDS             complement(155741..156190)
                     /locus_tag="ROH59_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDX4802706.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDTLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDALLQEQSAQRVGEMLLIDASENPEPETESNPWVEHWGTMLS"
     gene            complement(156208..156990)
                     /gene="truC"
                     /locus_tag="ROH59_000162"
     CDS             complement(156208..156990)
                     /gene="truC"
                     /locus_tag="ROH59_000162"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HDX4802707.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLA
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            complement(156990..157319)
                     /locus_tag="ROH59_000163"
     CDS             complement(156990..157319)
                     /locus_tag="ROH59_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HDX4802708.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWRNDEPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNNQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
     gene            complement(157941..158486)
                     /gene="syd"
                     /locus_tag="ROH59_000164"
     CDS             complement(157941..158486)
                     /gene="syd"
                     /locus_tag="ROH59_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HDX4802709.1"
                     /translation="MDDLTARALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            158554..159402
                     /gene="queF"
                     /locus_tag="ROH59_000165"
     CDS             158554..159402
                     /gene="queF"
                     /locus_tag="ROH59_000165"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HDX4802710.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQLAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKVSVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATSGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPST
                     TRLVRQ"
     gene            159514..160878
                     /gene="ppnN"
                     /locus_tag="ROH59_000166"
                     /gene_synonym="ygdH"
     CDS             159514..160878
                     /gene="ppnN"
                     /locus_tag="ROH59_000166"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HDX4802711.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
     gene            161435..162724
                     /gene="sdaC"
                     /locus_tag="ROH59_000167"
     CDS             161435..162724
                     /gene="sdaC"
                     /locus_tag="ROH59_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HDX4802712.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPIIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
     gene            162782..164149
                     /gene="sdaB"
                     /locus_tag="ROH59_000168"
     CDS             162782..164149
                     /gene="sdaB"
                     /locus_tag="ROH59_000168"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HDX4802713.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     DSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            164261..165016
                     /gene="xni"
                     /locus_tag="ROH59_000169"
     CDS             164261..165016
                     /gene="xni"
                     /locus_tag="ROH59_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HDX4802714.1"
                     /translation="MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTH
                     AVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNE
                     ADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
                     QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(165121..166269)
                     /gene="fucO"
                     /locus_tag="ROH59_000170"
     CDS             complement(165121..166269)
                     /gene="fucO"
                     /locus_tag="ROH59_000170"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HDX4802715.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLDVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTDEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(166297..166944)
                     /gene="fucA"
                     /locus_tag="ROH59_000171"
     CDS             complement(166297..166944)
                     /gene="fucA"
                     /locus_tag="ROH59_000171"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HDX4802716.1"
                     /translation="MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTG
                     IPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
                     EANLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            167491..168807
                     /gene="fucP"
                     /locus_tag="ROH59_000172"
     CDS             167491..168807
                     /gene="fucP"
                     /locus_tag="ROH59_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDX4802717.1"
                     /translation="MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYA
                     FGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAI
                     VLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALI
                     AMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN"
     gene            168840..170615
                     /gene="fucI"
                     /locus_tag="ROH59_000173"
     CDS             168840..170615
                     /gene="fucI"
                     /locus_tag="ROH59_000173"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HDX4802718.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVRKPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGKPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
     gene            170724..172142
                     /gene="fucK"
                     /locus_tag="ROH59_000174"
     CDS             170724..172142
                     /gene="fucK"
                     /locus_tag="ROH59_000174"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HDX4802719.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTDCHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAVVMDNIERLISAQQLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATSIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDT
                     SLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTTQLQRNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            172144..172566
                     /gene="fucU"
                     /locus_tag="ROH59_000175"
     CDS             172144..172566
                     /gene="fucU"
                     /locus_tag="ROH59_000175"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HDX4802720.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            172624..173355
                     /gene="fucR"
                     /locus_tag="ROH59_000176"
     CDS             172624..173355
                     /gene="fucR"
                     /locus_tag="ROH59_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HDX4802721.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(173399..174499)
                     /gene="rlmM"
                     /locus_tag="ROH59_000177"
     CDS             complement(173399..174499)
                     /gene="rlmM"
                     /locus_tag="ROH59_000177"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HDX4802722.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(174492..174887)
                     /locus_tag="ROH59_000178"
     CDS             complement(174492..174887)
                     /locus_tag="ROH59_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HDX4802723.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            complement(174906..175823)
                     /gene="gcvA"
                     /locus_tag="ROH59_000179"
     CDS             complement(174906..175823)
                     /gene="gcvA"
                     /locus_tag="ROH59_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HDX4802724.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGENPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            complement(176174..176401)
                     /locus_tag="ROH59_000180"
     CDS             complement(176174..176401)
                     /locus_tag="ROH59_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HDX4802725.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            176593..177798
                     /gene="csdA"
                     /locus_tag="ROH59_000181"
     CDS             176593..177798
                     /gene="csdA"
                     /locus_tag="ROH59_000181"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HDX4802726.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEASRQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNASDDKNIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKPELLEAMSPWLGGGKMVHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLTDYDINQAESWSRSLATLAEEALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            177798..178241
                     /gene="csdE"
                     /locus_tag="ROH59_000182"
     CDS             177798..178241
                     /gene="csdE"
                     /locus_tag="ROH59_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HDX4802727.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLTQWEDKYRQLIMLGKQL
                     PALPEELKAQAKEIAGCENRVWLGYTVAENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TAAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAAAKQV"
     gene            complement(178292..179098)
                     /gene="tcdA"
                     /locus_tag="ROH59_000183"
     CDS             complement(178292..179098)
                     /gene="tcdA"
                     /locus_tag="ROH59_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HDX4802728.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMNAGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(179175..180272)
                     /gene="mltA"
                     /locus_tag="ROH59_000184"
     CDS             complement(179175..180272)
                     /gene="mltA"
                     /locus_tag="ROH59_000184"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HDX4802729.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGVDNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            180481..180557
                     /locus_tag="ROH59_000185"
     tRNA            180481..180557
                     /locus_tag="ROH59_000185"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:180515..180517,aa:Met,seq:cat)
     gene            180591..180667
                     /locus_tag="ROH59_000186"
     tRNA            180591..180667
                     /locus_tag="ROH59_000186"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:180625..180627,aa:Met,seq:cat)
BASE COUNT        44036 a        47643 c        44995 g        44096 t
ORIGIN      
        1 gaaaaatata aaaactttat cgttcgctca tttttcaggc aaaacatctt aaatatagtc
       61 ttttccgtct aacttataga caaaaacgag ccccgaaggg ctcgttttat catttactgg
      121 acggcgacaa tccggtcttc attaacttcc aggcgaatca ctttacccgg aaccaattca
      181 ccagacagta tttgctgtgc cagcgggttt tcaatctgct gctgaattgc acgtttcaga
      241 ggacgtgcgc catagaccgg atcgtaaccg ttctcgctca gcagtttcag cgcctcgtca
      301 gaaatgtgga tttcataacc acgttcttcc agacgtttat acagacgttt caactgaatc
      361 tgcgcaatcg acgcaatgtg ctgttcaccc agcggatgga agaccaccac ttcatcgata
      421 cggttaatga attccggacg gaagttatgg ctaaccacac cgagcaccag ctctttcatg
      481 tgcgcataat ccagttcacc gaagcgttcc tgaatcaaat cggaaccgag gttagaggtc
      541 ataatgacaa ccgtattacg gaagtcgacc gttctcccct gcccgtcagt cagacgccca
      601 tcatccagta cctgcaacag aatgttgaag acatccggat gcgctttttc cacttcatcc
      661 agcagaatga cggaatacgg acgacgacgc accgcttcgg tcaggtagcc accttcttca
      721 taaccgacat atcccggagg cgcaccaacc agacgagaca ccgagtgttt ctccataaac
      781 tcggacatat cgatacggac catcgcctcg tcgctatcaa acataaagtt cgctagcgcc
      841 ttacaaagct cagttttccc cacaccggtt gggccgagga acaggaatga accaatcggg
      901 cgatttggat ccgccagccc cgcacggcta cgacgaatag cgttagatac cgcatcaacc
      961 gcttcgttct gaccaataac gcgatggtgc agttcttgct ccatacgcag cagtttttcg
     1021 cgctcgcttt ccatcatgcg agaaaccgga atccccgtcc aacgcgccag cacttcagca
     1081 atttcggcat cggtcacttt attacgcaac agacgcatag ttttgccttc gagctgcgtt
     1141 gcggcttcca gttgcttttc cagttccggg attttgccgt attgcagttc agacatccgc
     1201 gccaggtcac ccacacggcg agcctgttca atagcaattt tcgcctgttc cagttccgct
     1261 ttaatggtct gcgtaccaga aagcgaggct ttctctgctt tccactcttc ttctaactcg
     1321 gagtactgac gttctttgtc gctcagttct tcgttgagca tatccaggcg ttttttactg
     1381 gcttcatcag actctttcat taacgcctgt tgttccagtt tgagctggat gatacggcga
     1441 tcgagtcggt cgagttcttc tggttttgag tcaatctgca tacgaatgct ggatgctgct
     1501 tcatcgatca ggtcgatggc tttatccggc agctgacggt cagcaatgta gcgatgagac
     1561 aacgtcgctg ctgcaacaat tgccgggtca gtaatttgca catggtggtg cagctcgtaa
     1621 cgttctttca ggcctcgcag aatagcaatg gtatcttcaa cagaaggctc ggcaacaaac
     1681 actttctgga aacgacgttc cagcgcagca tctttttcga tgtactggcg atattcgtca
     1741 agcgtcgtgg cacctacgca gtgcaattca ccacgcgcca acgctggttt cagcatgttt
     1801 ccggcgtcca ttgcgccatc ggctttaccc gcgccgacca tggtatgtaa ttcgtcgata
     1861 aacaggatga cgttgccttc ctgtttagca agatcgttaa gtacgccttt taaacgttct
     1921 tcaaactcac cgcgatattt cgccccagcc accagcgcgc ccatatccag cgccagtacg
     1981 cggcggcctt tcaacccttc gggcacttcg ccgttgataa tacgctgcgc cagaccttca
     2041 acgatggcag ttttaccgac gccgggttca ccaatcaata ccgggttatt tttagtacga
     2101 cgttgcagca cctgaatggt acggcgaatt tcttcatcac gaccaatcac cggatcgagt
     2161 ttgccttgtt cggctcgttc ggtaaggtcg atggtatatt ttttcaaagc ctgacgttgg
     2221 tcttcagcac cttgatcgtt cacgctttca cctccacgca tttgttcaat cgcttgagta
     2281 atgttggcgg tggtcgcccc tgctgctttc aggatgtcgg ccagcgtgcc gcgagactca
     2341 agtgccgcca gaacgaacag ttctgacgag ataaagttat caccacgttt ttgcgccagc
     2401 ttgtcgcaaa gattaagaac gcgcaccaga tcctgtgatg gctggacatc accaccagta
     2461 ccttcaacct gtggtaaacg atttaatgcc tgattgatat ctgtgcgcaa ctggccagca
     2521 ttaatgccag cggatgttaa taaaggacta accgaacccc cttcctgatt cagcagggcg
     2581 ctcattaaat gaagtggttc gatgaattgg ttgtcgtgcc cgagtgcaag tgattgggca
     2641 tcggcaagag caagctggaa tttattagta agacgatcca gacgcataac tcctcccata
     2701 acggatcaaa gttgctactg gagattaaat gaggtcatcc ctcaattatt caaggttatt
     2761 gaccagatta atgtgaaaag aaaatcacgc gtaccggatc gtcttgattc tttaggttat
     2821 atcagccaaa tgaaacttgc catacgaccg gtggtcttgt cgcgacgata agagaagaaa
     2881 gtctcatttt ccgtatatgt acaacggtcg ccgccgaaaa tttgttcaac accaacgctc
     2941 gccagacgct gccgggcaag ctgataaata tccgccagat acttatcacc atgctgaatg
     3001 aaagctgtac tcgctttggc gtctactgcc ataaacgcct cgcgaacctc cgcccccact
     3061 tcgaacgcac gtggcccaat tgccggccct aaccaggcga gaatattttc cggattatca
     3121 gcaaaacagg aaaccgtctc ttccaacacg cctgcgcaca gtccacgcca gccagcatga
     3181 gcggcggcga cctccgttcc cgcacgattg caaaacagca cgggcaggca gtcggcagtc
     3241 atcactgcgc aaaccgtgcc aggcgtattg ctataagagg catctgctcg ttttgaggca
     3301 taaggttcgc caataagctt aagcacgtct ttgccgtgta cctgctcaag ccagaccggt
     3361 ttagaaggca aattgcccgc agcaaaaagt cgcttgcgat tctccccaac gtgatccggg
     3421 ttatcgccac aatgggcacc gaggttgagc gagtcatacg ggggtaagct cacaccgccg
     3481 atacgggtag agctacaagc cgcaacacct tttggcagcg gccactgcgg gacaatcagc
     3541 ttactcataa ccagtccact tcatccttat gctcttcgaa atcggcgcgc atctcctcaa
     3601 tcagctccac catatcttgt ggaataggcg catgccattc catttcgatg ccggagatcg
     3661 ggtgataaag acgcagcatg gttgcatgaa gcgcctgacg gtcaaactta cgcagcgtgg
     3721 agataaacgc ttccgaagca ccttttggcg gacgcggacg tccaccataa accggatcgc
     3781 ccaccagcgg atgagtgata tgggccatat gcacgcggat ctggtgcgta cgtccggttt
     3841 ccagacgcaa ccgcagacgc gtgtgcacac ggaagtgttc catgatgcga tagtgagtga
     3901 ccgccggttt acccatggga tgtaccgcca tgtgagtacg tttggtcggg tggcggctga
     3961 ttggttcatc tactgtaccg ccagcggtca tatgaccaat tgccaccgct tcatactcac
     4021 gtgtaatttc acgccgttgc aaagattcga ctaaacgcgt ctgagccgga acggtttttg
     4081 ccacaaccat caggccagtg gtgtctttat ccagacgatg gacaatgccc gcacgcggta
     4141 catcggcaat gggcggataa taatgaagca atgcattcag taccgtgcca tccgggttac
     4201 ccgcgccagg atgtaccacc aggtcgcgcg gtttattaat aacgatgata tcttcatctt
     4261 catagacgat atccagcggg atatcctgcg gttcaaaacg cgcttcttct tcaatctcag
     4321 cgttgatggc aacctgctcg ccacccaata ctttttcttt cggcttatca cacactttgc
     4381 cgttaaccag cacacgctgg tcgaggatcc attcttttat ccgcgaacgt gaataatccg
     4441 ggaacatttc ggccaaagcc tgatctaagc gttgaccgag ttggttttcg gacaccgttg
     4501 cagtgagctg tactcgttgt gccatatata ctgcttcttc gtttatcgtt ggggttttac
     4561 ggctttgccg tttaatatag tgtgctattg tagctggtct taaccgggag caggaacaga
     4621 gaatctcccg tattacattt tgaggaaagt caaaacgtca tgacgcgcat gaaatatctg
     4681 gtggcagccg ccacactaag cctgtttttg gcgggttgct cggggtcaaa ggaagaagta
     4741 cctgataatc cgccaaatga aatttacgcg actgcacaac aaaagctgca ggacggtaac
     4801 tggagacagg caataacgca actggaagcg ttagataatc gctatccgtt tggtccgtat
     4861 tcgcagcagg tgcagctgga tctcatctac gcctactata aaaacgccga tttgccgtta
     4921 gcacaggctg ccatcgatcg ttttattcgc cttaacccga cccatccgaa tatcgattat
     4981 gtcatgtaca tgcgtggcct gaccaatatg gcgctcgatg acagtgcact gcaagggttc
     5041 tttggcgtcg accgtagcga tcgcgatcct caacatgcac gagctgcgtt tagtgacttt
     5101 tccaaactgg tgcgcggcta tccgaacagt cagtacacca ccgatgccac caaacgtctg
     5161 gtattcctga aagatcgtct ggcgaaatat gaatactccg ttgccgagta ttatacagaa
     5221 cgtggtgcat gggttgctgt cgttaaccgc gtagaaggca tgttgcgcga ctatccggat
     5281 acccaggcta cgcgtgatgc gctgccgctg atggaaaatg cataccgtca gatgcagatg
     5341 aatgcgcaag ctgaaaaagt agcgaaaatc atcgccgcaa acagcagcaa tacataacag
     5401 aaacctgaaa cacaaaacgg cagccttgag ctgccgtttt tttattctgt tagttgtgaa
     5461 actgaagcga tttagtcact atcgatctca tcaaatatgg cccgctttga gatattcctc
     5521 aagtaaaaaa acacctcttc ctgcgatttc tcacaaaaaa gattcgttga caaaaagtga
     5581 caaaattatg agatttccat cacacatttt gacatcagga acgttatgct gaattcacca
     5641 agacgggaag acaagaggta aaatttatga caatgaacat taccagcaaa caaatggaaa
     5701 ttactccggc catccgccaa catgtcgcag accgtctcgc caaactggaa aaatggcaaa
     5761 cacatctgat taatccacat atcattctgt ccaaagagcc acaagggttt gttgctgacg
     5821 ccacaatcaa tacacctaac ggcgttctgg ttgccagtgg taaacatgaa gatatgtaca
     5881 ccgcaattaa cgaattgatc aacaagctgg aacggcagct caataaactg cagcacaaag
     5941 gcgaagcacg tcgtgccgca acatcggtga aagacgccaa cttcgtcgaa gaagttgaag
     6001 aagagtagtc ctttatattg agtgtatcgc caacgcgcct tcgggcgcgt tttttgttga
     6061 cagcgtgaaa acagtacggg tactgtacta aagtcactta aggaaacaaa catgaaacac
     6121 acaccgtttt tcttcgcatt cttttttacc ttcccctgaa tgggaggcgt ttcgtcgtgt
     6181 gaaacagaat gcgaagacga acaataaggc ctcccaaatc ggggggcctt ttttattgat
     6241 aacaaaaagg caacactatg acatcggaaa acccgttact ggcgctgcga gaaaaaatca
     6301 gcgcgctgga tgaaaaatta ttagcattac tggcagagcg acgcgaactg gtcgtcgagg
     6361 tgggaaaagc caaactgctt tcgcatcgcc cggtacgtga tattgatcgt gaacgcgatt
     6421 tgctggaaag attaattacg ctcggtaaag cgcaccatct ggacgcccat tacattactc
     6481 gcctgttcca gctcatcatt gaagattccg tattaactca gcaggcttta ctccagcaac
     6541 atctcaataa aattaatccg cactcagcac gcatcgcttt tctcggcccc aaaggttctt
     6601 attcccatct tgcggcgcgc cagtatgctg cccgtcactt tgagcaattc attgaaagtg
     6661 gctgcgccaa atttgccgat atttttaatc aggtggaaac cggccaggcc gactatgccg
     6721 tcgtaccgat tgaaaatacc agctccggtg ccataaacga cgtttacgat ctgctgcaac
     6781 ataccagttt gtcgattgtt ggcgagatga cgttaactat cgatcattgt ttgttggtct
     6841 ccggcactac tgatttatcc accatcaata cggtctacag ccatccgcag ccgttccagc
     6901 aatgcagcaa attccttaat cgttatccgc actggaagat tgaatatacc gaaagtacgt
     6961 ctgcggcaat ggaaaaggtt gcacaggcaa aatcaccgca tgttgctgcg ttgggaagcg
     7021 aagctggcgg cactttgtac ggtttgcagg tactggagcg tattgaagcg aatcagcgac
     7081 aaaacttcac ccgatttgtg gtgttggcac gtaaagccat taacgtttct gaccaggttc
     7141 cggcgaaaac gacgttgtta atggcgaccg gacaacaagc tggtgcactg gttgaagcgt
     7201 tgctggtact gcgcaaccac agtctaatta tgacccgtct ggaatcacgt ccgattcacg
     7261 gtaatccgtg ggaagagatg ttttatctgg atattcaggc caatcttgaa tcagcggaaa
     7321 tgcaaaaagc attgaaagag ttaggggaaa tcacccgttc gatgaaggta ttgggctgtt
     7381 acccaagtga gaacgtagtg cctgttgatc caacctgatg aaaaagtgcc ggatgatgtg
     7441 aatcatccgg cactggatta ttactggcga ttgtcattcg cctgacgcaa taacacgcgg
     7501 ctttcactct gaaaacgctg tgcgtaatcg ccgaaccagt gctccacctt gcggaaactg
     7561 tcaataaacg cctgcttatc gccctgctcc agcaactcaa tcgcctcgcc gaaacgctta
     7621 tagtaacgtt tgattaacgc cagattacgc tctgacgaca taataatgtc ggcataaagc
     7681 tgcggatcct gagcaaacag tcgcccgacc atcgccagct caaggcggta aatcggcgaa
     7741 gagagcgcca gtagttgctc aagctgaaca ttttcttctg ccaggtgcag cccataagca
     7801 aaagtagcaa agtggcgcag agcctgaata aacgccatat tctgatcgtg ctcgacagcg
     7861 ctaatacgat gcaaccgagc gccccagacc tgaatttgct ccagaaacca ttggtatgct
     7921 tccggcttac gtccatcaca ccagaccaca acttgctttg ccaggctacc gctgtccggg
     7981 ccgaacatcg ggtgtaaccc cagcaccggg ccatcgtgcg ccgccagcat ggcctgtaat
     8041 ggtccatttt tcactgatgc cagatcaacc agaatacaat ctttcggtaa aggcggtaat
     8101 ttgccgataa cttgctcagt aacgtggatg ggcacactaa caatcaccat tccggcatcg
     8161 gcaacaatat cagccgctcg atcccagtca tgttgctcca gaatccgcac ctgataaccc
     8221 gagagtatca gcatcttctc gaacagacgt cccatctgac cgccaccacc gacgataacc
     8281 accgggcgca gtgacggaca aagcgtttta aatcctttgt cgttttcact ggagtaagat
     8341 tcacgcatca cccgacgcaa aacatcctca atcagatctg gcggtacacc cagagcttcc
     8401 gcctccgcac gacgcgaggc caacatagat gcctcgcgct ccggaacata aataggcagt
     8461 ccaaatcggc ttttcacctc gcccacttca gcaaccaatt ccagacgctt cgctaataaa
     8521 ttcagcagcg ctttatcgac ttcatcaatt tgatcgcgta atgcggtcaa ctcagcaacc
     8581 ataataaacc tcttaagcca cgcgagccgt cagctgcccg ttcagatcct gatgaatttc
     8641 acgcagcaag gcatcggtca tttcccagct aatgcaggca tcggttacgg atacaccgta
     8701 tttcatttca ctgcgcggtt gctcggaaga ctgattgccc tcgtggatat tactttcgat
     8761 catcagacca ataattgagc gattgccatc tttgatttga gcaaccacgg attctgccac
     8821 cgcaggctga cggcgataat ctttattgga attaccgtgg ctgcaatcta ccatcagaga
     8881 cgggcgcagt cccgcctgtt ccatctcttt ttcacattgc gcaacatccg cagggctata
     8941 gtttggcgct ttaccaccgc gcaggatcac atgcccgtcc ggattcccct gagtttgtag
     9001 caacgcaacc tgccctgcct ggttaatgcc aacaaaacgg tgcggctggg cggcggcgcg
     9061 catagcgtta attgccgttg ccagactgcc atcggtgccg tttttaaaac caaccggcat
     9121 ggaaagcccg gaggccattt cacggtgagt ttgcgattcc gttgtacgag caccaattgc
     9181 tgaccagcta aacagatcgc ccaggtattg cgggctattc ggatctaacg cttccgtcgc
     9241 cagtggcagt cccatattca ccagctcaag cagcaattta cgcgcgatct gcagcccggc
     9301 ttctacatca aaagagccat ccatatgggg atcgttaatt aaccctttcc agccgacagt
     9361 ggtacggggt ttttcaaaat agacgcgcat taccagatag aggctatcgc tgacctctgc
     9421 ggcaagggct ttaaatcgac gagcatattc cagagcagtt tccggatcat gaatggaaca
     9481 aggaccacat actaccagaa gacgaggatc gcgcccggcg ataatatctg aaatggtttt
     9541 acgcgagtca gcaatctggg cttcttgttg caggcttaat ggaaaagcgg ccttcagttg
     9601 ttccggagtc attaaaacct gttcgtcggt aatatgtacg ttattcagcg cgtctttttg
     9661 catgatggcg atcctgttta tgctcgtttg cgatagttga tcctcagcga ggatgacgta
     9721 acgataacac ataaagtaaa gttttcaatc catatttcgt acacatttct ttacgtaagc
     9781 aatttattcg cgctttttac ccttatttct gtatatataa atttacacca tctttaaaaa
     9841 caatccgcta tgctttgaaa aaggagaaag aaatgatgaa aaaatttatc gcccccttgt
     9901 tggctttact ggttagcgga tgtcagattg atccttatac tcacgcgcca accttgacca
     9961 gcaccgactg gtatgatgtt ggtatggaag atgcgatatc gggcagcgcc attaaagatg
    10021 acgatgcatt tagcgattca caggcggatc gcggtctata ccttaaagga tatgccgaag
    10081 ggcaaaagaa aacttgccag accgatttta cttatgcccg ggggctttct ggtaaaagct
    10141 ttcctgccag ctgcaataat gttgaaaatg ccagccaact gcatgaagta tggcgaaaag
    10201 gggctgatga aaatgccagc acaatacgat taaattaatt acccccaaaa taaattaagc
    10261 atgagatttt actcattatg ttttatttct cacattgatg acgaccgcat gaaaggatga
    10321 tattttaatg agcattctga aaaaatatcg atgcatttcg agcgaagatg gtgaggatcc
    10381 ctgaatgcgt ttttctcacc gactgttctt actgctgatt ctcctgctga cgggagcacc
    10441 aatactcgct caggaacctt ctgacgttgc gaaaaacgtg cgtatgatgg tttccggtat
    10501 tgtcagttac acccgctggc ctgggctatc agggccacca aagttatgta tcttttcatc
    10561 ttcacgtttt agtaccgcct tacaagaaaa tgctgctaca tctttacctt atctgcctgt
    10621 catcattcat actcaacaag aggcgataat ttcaggctgc aatggttttt attttggcaa
    10681 cgagtcaccg acattccaga tggaattaac cgaacaatat ccgtcaaagg cgttattatt
    10741 aattgccgaa caaaataccg agtgcattat tggtagcgcc ttttgtctga tcatccacaa
    10801 taatgacgtc agatttgccg taaacctgga tgccttatcg cgtagcggtg taaaggtcaa
    10861 cccggatgtc ttaatgctcg cacggaagaa aaatgatgga taacgataat tctcttcata
    10921 agcgccccac gtttaaaaga gcattacgca acatcagcat gaccagcata tttatcacta
    10981 tgacgctgat ctggctgctg ctttccgtga cgtcagtgct aaccctgaaa caatacgcgc
    11041 aaaaaaacct ggcactgaca gcagcaacaa tgacttacag tctggaagca gctgtcgttt
    11101 ttgccgatgg ccctgcagca actgaaacac tggcagcgct gggccagcaa ggccaatttt
    11161 caactgcaga agtgcgtgat aagcagcaaa atattctggc atcctggcat tacacccata
    11221 aggaaccagg cgatactttc agcaatttca taagccactg gctcttccct gcccccatca
    11281 ttcagccgat tcgtcacaat agtgaaacca ttggcgaagt acgcttaact gctcgcgaca
    11341 gttcaatcag ccattttatc tggttttcgc tcgctgtcct gaccggttgt attctgctgg
    11401 catcaggcat cgcaattacc ctcacccgcc atttgcacaa tggcctggtg gaagcgctga
    11461 aaaatatcac cgatgtcgta catgatgtgc gttctaaccg caatttttcc cgacgagttt
    11521 cggaagaacg tatcgctgag tttcaccgct tcgctctcga cttcaacagt ctgctggatg
    11581 aaatggaaga gtggcagctt cgtttacagg ccaaaaatgc gcagcttcta cgtaccgcgc
    11641 tacatgaccc attaaccggg ctggctaacc gcgcagcgtt tcgtagcggc atcaacacgt
    11701 tgatgaacaa ttccgatgcc cgaaaaacgt cggcgttact atttcttgat ggcgataatt
    11761 tcaaatatat caatgatacc tggggtcatg cgacgggcga tagagtcttg attgaaatag
    11821 caaaacggtt agctgaattt ggcgggctgc gacataaagc ataccgcctg ggcggcgatg
    11881 aattcgctat ggtgctctat gatgtacagt cggaatctga agtgcagcag atatgctcag
    11941 cactgacaca aatttttaat ctcccgtttg atcttcataa tggccatcaa actaccatga
    12001 cattaagcat tggttacgcg atgaccattg agcacgcctc tgcggaaaat ttacaagagc
    12061 ttgccgatca caatatgtat caggccaaac accagcgtgc cgaaaaactg gtgagataac
    12121 aaggatatat cgatatgata aagcacctgc tagcccccct gattttcacc tcgctaatac
    12181 ttactggctg ccagtcccct cagggaaagt ttactcctga gcaagtcgcc gctatgcaat
    12241 cttatggatt tactgaatcc gccggcgact ggtcgctggg cttatcagat gccattctgt
    12301 tcgcaaaaaa tgactacaaa ttgctcccgg aaagccagca acaaatccaa accatggcag
    12361 ccaaattggc ctcgacaggg ctaacacatg cccgtatgga tggacacacc gacaactatg
    12421 gtgaagacag ttacaacgaa gtcttatcat taaaacgggc gaatgtcgtg gccgatgcat
    12481 gggctatggg tggacaaatt ccgcgcagca atctcatcac acagggttta ggaaaaaaat
    12541 atcccatagc cagtaacaag accgcccagg gccgcgccga aaaccgccgc gtcgcagtgg
    12601 tgattacaac cccttaaaac acgagcaaac agacaaaaaa agggccagcc aattggccag
    12661 cccttcttaa caggatgtcg cttaagcgaa atcttagtta agacgctctt tgatacgagc
    12721 agccttacca gtacgctcac gcaggtagta cagtttagct ttacgaacag caccacgacg
    12781 tttgacagaa atgctgtcaa ctaccggaga gtgagtctgg aagacacgct caacgccttc
    12841 gccgttggaa attttacgaa cagtgaatgc agagtgcaga ccgcggttac gaattgcgat
    12901 aaccacgccc tcgaatgcct gcagacgttt tttggaacct tcaacaaccc atactttcac
    12961 ttccacggta tcacccggac ggaaggaagg tacgtcctgc ttcatctgct cttgttcaag
    13021 ttgcttaata atgttgctca taatttaatc tcttatcctg ggtaaactga tatctcgggg
    13081 gcttacgcca tcccatcatg tttatgttgc tgttgtgcgt gttccgtttt gaactccgcc
    13141 agcaaccttg cttgctcttc agtcagagcc aggttttcca gaagttcagg tcttctaagc
    13201 caggtacggc ccagcgactg tttcaaacgc cagcgacgta tctcggcatg gttgcccgac
    13261 agtaacactg gcggaacttc catcccttct aacacctcag gccgcgtata gtgcgggcaa
    13321 tccagcaatc cttcagcaaa ggagtcttcc gttgccgagg cctcatgtcc cagtactccc
    13381 ggaataaacc gggaaacgga gtcaatcagc gtcattgctg gtaactcacc accactgaga
    13441 acgtaatcgc cgattgacca ttcttcatca atttcggttt ggatcacgcg ctcatctata
    13501 ccttcgtagc gaccgcacac cagaatcaat ttttgattcg ttgccagctc gctgacgccc
    13561 gcttgatcaa gcttgcgtcc ctgtggtgac agataaatca cctttgcgcc ttcacccgcc
    13621 gcggcttttg ctgcatgaat ggcgtcccgc aagggttgca ccatcattaa catccccggt
    13681 ccgccgccgt aaggacgatc gtccacggta cggtgccgat catacgtgaa gtcgcgagga
    13741 ctccagctct ggatgctcag caggccattt ttaactgccc ggccagttac cccgtaatcg
    13801 gtaattgcgc ggaacatttc aggaaacagg ctaattatgc caatccacat agcgccgtct
    13861 tttaccgttt atccggtggt ttaaaaacca ggatcccaat ctacttcgat tgaacgagta
    13921 gtgagatcga ctttcttgat aacctgccca tcgaggaacg gtacgagacg ttccttgata
    13981 ccaaacgcat ctttcaggtt tgccttaatg acgagaacgt cattagatcc ggtttccatc
    14041 atatctacga ctttaccgag atcgtagcct tcagtggtta ctacctggca gcccatcagg
    14101 tctttccagt agtagtcacc ctcttcaagc tgaggcaact gcgatgaatc cacgacaatt
    14161 tcacaattcg tcagcaggtt cgccgcatca cgatcgtcaa cgcctttcag cttgatgatc
    14221 atgtcctgat tgtggtgctt ccagctttcc agctggactt gctgccactg acccgccttc
    14281 tggataaacc agggctgata gtcaaaaatg ctttcggcgt cttcggtgga agaaaacact
    14341 ctgagccacc cacgaatacc gtaagacgaa cccatttttc ccaaaacgat gggatcaaca
    14401 ggtgcttgcg cggtgagttg tttgctcatc atgaccaccg tgacagatta agctgctttg
    14461 tttacttctt tgatcagcgc agcaacgcga tcagaaatag ttgcgccctg gccaacccag
    14521 tgagcgatgc gatccagatc caggcgagtg ccttcttctt tttcgctagc gattgggttg
    14581 aagaaaccaa cgcgctcgat gaagcgaccg ttgcgtgcat tacggctgtc agcgacaaca
    14641 acctggtaga acggacgctt tttagcgccg tgacgtgcta aacgaatagt taccataaca
    14701 tcctcttgtg tgaataaaac aaccggaccc catcgaggaa cggagtccgg tgtcatatta
    14761 aaagcccgaa aattttactg atttctggag aaaatgcaat cagcagttaa taactctgtc
    14821 gcataaggtc atttagcgac caggaaatcc cggcggcatc atccctttca tgcttctcat
    14881 catcttcgcc atcccgccct tcttcatttt cttcatcatg cgctgcatgt cgtcgaactg
    14941 tttcagaaga cggttaacgt cctgcacctg cataccgcaa ccggcagcga tacggcgctt
    15001 acgcgaacct ttgatgattt ctggcttagc gcgctctttc atcgtcatcg agttgatgat
    15061 ggcttccata cgcaccagca ctttatcgtc catctgcgac ttgacgttat ccgggatctg
    15121 ccccatgccc ggcagcttgc ccatcaggct agccatgccg cccatatttt tcatctggcg
    15181 cagctgctca agaaagtcgt tgagatcgaa gccgtcgcct tttttcagct tgctggctaa
    15241 tttctcagct tgcgcgcggt caactttgct ttcgatatct tcgatcagtg acagtacgtc
    15301 gcccatgccg agaatacggg aggcaatacg gtccggatgg aatggctcca gcgcctcggt
    15361 tttctcgcca acaccgagga acttgatcgg tttgccagtg atgtgacgaa tagagagcgc
    15421 cgcaccgccg cgggcatcgc cgtccacttt ggtcaacact acaccggtaa gcggtaacgc
    15481 ttcattgaat gcttttgccg tattggccgc atcctgaccg gtcatggcat cgaccacaaa
    15541 tagggtttca accggattaa tcgacgcatg gacttgtttg atctcgtcca tcatcgcttc
    15601 gtcaacgtgc agacgaccgg cagtatccac cagcagcacg tcgtagaatt tcagtttggc
    15661 ttctttcagc gccgcgttaa cgatatctac cggcttctga ccaacatcag aagggaagaa
    15721 atcaacgccc acctgctctg ccagcgtctc aagctgtttg attgccgccg ggcgatagac
    15781 gtcggcagaa accaccagta ctttcttctt gtgcttctcg cgcaggaact taccgagttt
    15841 accaacgctg gttgttttac cggcaccttg caggcccgcc atcagcacga ccgcaggcgg
    15901 ttgcgcagcc aggttcaggg tctggttctc ttcgcccatc gccgcaacca gttcgttacg
    15961 gacaattttg acgaactcct gccccggcgt caggctctta ttaacttcat gaccaaccgc
    16021 tttctctttt acgcgattga taaactcacg cactaccggc agagcgacgt cagcctccag
    16081 cagcgccatg cgcacttcgc gcagcgtatc ttttacgttg tcttcagtga ggcgtccacg
    16141 gccactgata ttgcgcagcg tgcgcgacaa acgatcggtt aaattatcaa acattgtctc
    16201 tcgcctgggg tggaaacggt tggccgcaat cgcgacacat catcagtatt ttgccgcagt
    16261 ataacatgaa ggcgtctttg ttgttatgca acggttggag cagcgttcac ctgacgctat
    16321 actgcttctc tttcttattg ctcaaactgt cgacattact atgcccgttt ttgctctgct
    16381 cgcgcttgtc gcctactccg tcagtcttgc gctgattgtt cccggtctgc tgcaaaaaaa
    16441 cggcggctgg cggcgcatgg ctattatttc tgcggtcatc gcgctggtct gccacgcaat
    16501 cgctctggaa gcccgcatcc tgcccgacgg tgatagcgga caaaacctca gcctgctgaa
    16561 cgttggttca ttggtcagtt tgatgatctg tacggtaatg accattgtgg cttctcgcaa
    16621 tcgtggctgg ttgttgctac ccattgtcta tgcctttgcg cttatcaacc tagcgctggc
    16681 gacctttatg cccaatgaat acatcaccca tctggaagca acgccgggga tgctggtgca
    16741 cattggctta tcgctttttt cctatgccac gctaattatc gctgccctgt acgcgctgca
    16801 actggcgtgg attgattacc aactgaagaa caagaagctg gcgtttaacc aggaaatgcc
    16861 gccattgatg agtatcgagc gtaaaatgtt ccatatcacg cagattggcg tggtgctgct
    16921 aacgctcact ctttgcactg gcctgttcta catgcacaac ttatttagca tggaaaatat
    16981 cgacaaggcc gtgctctcta tcgtggcgtg gtttgtctat attgtgctgc tgtggggaca
    17041 ttatcatgaa ggatggcgtg gacgccgcgt cgtctggttt aacgttgcgg gtgcagtcat
    17101 tctgacactg gcctacttcg gcagccgaat ttttcagcag ttaatcagct aaacccagaa
    17161 aaggagtttc ccctggaaca catttctact actacgttga tcattattct gatcatcatg
    17221 gtggtcattt cagcctattt ttccgggtcc gaaaccggaa tgatgaccct caaccgctat
    17281 cgtctgcggc atatggcgaa acagggtaat cgctcggcca aacgcgtcga aaaattgctg
    17341 cgtaagccag accgcctgat aagcctggtg ttaatcggca ataacctggt caatattctt
    17401 gcctccgcgc tcggcactat tgttggaatg cgtttgtacg gcgatgcggg cgtggcaatt
    17461 gcgactggtg tgctgacttt tgtcgtgctg gtttttgctg aggtattgcc aaaaaccatt
    17521 gccgcgctgt acccggaaaa agtcgcttat ccgagtagtt ttctgctggc tccgctgcaa
    17581 attttgatga tgccgctggt ctggttgctg aatgctatta cccgcatgtt aatgcgcatg
    17641 atgggcatca aaaccgatat cgtggttagt ggctctttaa gcaaagaaga attacgcacc
    17701 attgtgcacg aatcgcggtc acaaatttcc cgtcgcaatc aggatatgct gctgtcggta
    17761 ctcgatctgg aaaagatgac cgtcgatgac atcatggtgc cgcgcagtga aattatcggt
    17821 attgatatca acgatgactg gaaatcgatt ctgcgccaac tctcccactc acctcacggg
    17881 cgcatcgtgc tctaccgtga ttcgctggac gacgccatca gtatgctgcg tgtgcgtgaa
    17941 gcctggcgac tcatgtcgga gaaaaaagag ttcaccaaag aaaccatgct acgcgccgcg
    18001 gacgagatct attttgtccc ggagggtacg ccgctcagca cacagttggt gaagtttcag
    18061 cgcaacaaaa agaaagtcgg cctggtcgtc aacgagtatg gagacattca ggggctggtg
    18121 acggtcgaag atattctcga agagattgtc ggcgatttca ccacgtcgat gtcgccaaca
    18181 cttgccgaag aggtcacgcc gcaaaacgac gggtcggtga ttatcgatgg caccgccaac
    18241 gtgcgagaaa ttaacaaagc ctttaactgg catctaccgg aagatgatgc tcgtactgtt
    18301 aacggcgtca ttctggaagc gctggaggag attccggtag caggcacccg cgtgcgtata
    18361 ggcgagtacg atatcgatat tctcgacgta caggacaata tgattaagca ggtaaaagtt
    18421 tttcctgtaa aaccgctgcg cgagagtgtg gcggagtaaa aaaacggccc ggcattcgca
    18481 tgctggaccg tgatttatta cgaaaacaga aattaagctt ttgccttcgc tacagtcacc
    18541 atcgccgcac gaattgtacg accgttcagc gtataaccct tctgcataat gcccagtacg
    18601 ttacctggcg caacgtcatc agattccacc attgcgatgg cctgatgcac attcgggtcc
    18661 agtggtacgt tagtttcggc gatcacttca acgccaaact tacgcacaac atccagcatc
    18721 gacttcagcg tcagctcaat accttcaacc atcgcggaca tatccgggtt agctttatca
    18781 gccacttcca gcgcacgatc caggctatca atcaccggca gcaattcgtt gatgaatttc
    18841 tccagcgcga atttgtgagc tttttcaata tccagttcag tacgacgacg caggttttcc
    18901 atttcggctt ttacgcgcaa aatgccgtca cgttcacggg tctgggcttc agccagctga
    18961 gcttcgagat tcgcaatttt ttcatcgcgc ggatccacct gctcagcaga agcttctggc
    19021 tcaactgcct caatctcttc gtgctgatcc atgataattt cttccggggc ttgcccctca
    19081 ggcgttttct gttctttact actcatgaat ttctccgcgt ttttttcgca ttcatctcgc
    19141 taacttcgct tattatgggg atcagtttca gggtttcaag ggaagcactc acattgtcat
    19201 caatcttcgc aacaaggacc tcggaaaaat gaataatcat ttcaagtgta ttggcattgt
    19261 gggacaccca cggcacccca ctgcactgac aacacatgaa atgctctacc gctggctgtg
    19321 cacaaaaggt tacgaggtca tcgttgagca acaaatcgct cacgaactgc aactgaagaa
    19381 tgtgaaaact ggcacgctcg cggagattgg gcaacaggct gatctcgcgg ttgtcgttgg
    19441 cggcgacggt aatatgctgg gcgcggcgcg cacgctcgcc cgctacgata ttaaagttat
    19501 tggaatcaac cgtggcaacc tgggtttcct gactgacctt gatcccgata acgcccagca
    19561 acaattagcc gatgtgctgg aaggccacta catcagcgag aaacgttttt tgctggaagc
    19621 gcaagtctgt cagcaagatt gccagaaacg catcagcacg gcgattaacg aagtggtact
    19681 tcatcctggc aaagtagcgc atatgattga gttcgaagtg tatatcgacg agatctttgc
    19741 gttttcgcag cgttccgatg gactgattat ttcgacgcca acaggctcca ccgcatattc
    19801 cctctctgcg ggcggtccta ttctgacacc ctctctggat gcgattaccc tggtgcccat
    19861 gttcccgcat acgttgtcag cacgaccact ggtcataaac agcagcagca cgatccgtct
    19921 gcgtttttcg catcgccgta acgacctgga aatcagttgc gacagccaga tagcacttcc
    19981 gattcaggaa ggtgaagatg tcctgattcg tcgctgtgat taccatctga atctgattca
    20041 tccgaaagat tacagttatt tcaatacatt aagcaccaag ctcggctggt caaaaaaatt
    20101 attctaattt tacgccagcc tctttactgt atataaaacc agtttatact gtacacaata
    20161 acagtaatgg tttttcatac aggaaaacaa ctatgttggc acaactgacc atcagcaact
    20221 ttgctatcgt tcgtgagctt gagattgatt ttcatagcgg catgaccgta ataactggcg
    20281 agaccggcgc gggtaaatct attgcaatag atgccctcgg cctttgtctc ggtggtcgcg
    20341 ctgaagccga catggtgcgt accggcgctg ctcgtgccga cctgtgcgcc cgtttttctc
    20401 tgaaagatac gccagcggcc ctgcgttggc tggaagaaaa ccagcttgaa gacgggcatg
    20461 aatgtttgct tcgtcgcgta atcagcagcg atggtcgctc ccgtggtttc atcaacggta
    20521 cagctgttcc tctgtcacaa ctgcgcgaac tgggtcagtt gctgattcag atccatggtc
    20581 agcacgctca tcagttactc accaaacccg agcaccaaaa attcctgctt gatggctatg
    20641 ccaatgaaac ctctcagctc caggaaatga ccgcacgtta tcagttgtgg catcaaagct
    20701 gccgtgacct cgcgcatcat cagcagttaa gtcaggaacg cgccgcccgt gcggagctgc
    20761 tgcaatacca attaaaagaa cttaacgaat ttaatccgca gcctggagag tttgagcaaa
    20821 tcgacgaaga gtacaaacgt ctggcgaaca gcggtcaatt gctgaccacc agccagaatg
    20881 cattggcatt aatggctgac ggtgaagacg caaatctgca aagtcaactt tacacggcta
    20941 aacaactggt gagcgaattg attggcatgg acagcaaact gtccggcgta cttgatatgc
    21001 tggaagaggc taccatccag attgctgaag ccagtgatga actacgccac tactgcgatc
    21061 gtctggatct cgatcccaac cgactgtttg aacttgaaca gcgcatctca aaacagattt
    21121 cgctggcacg taaacatcac gtcagccctg aggcattgcc acagtattac cagtcgctac
    21181 tggaagaaca gcagcaactg gacgatcagg ccgactcaca agaaacgctc gcgctggcgg
    21241 taacgaaaca tcatcagcag gcactggaaa cggcgcgcgc gttacaccag caacgccagc
    21301 attatgcaaa tgagttggca cagctgatca ccgatagtat gcatgcactc tctatgccac
    21361 atgggcagtt tacgatcgat gttaaatttg acgagcatca cctgggcgct gacggcgctg
    21421 atcgtattga gtttcgggta accaccaacc caggtcagcc aatgcagcct attgccaaag
    21481 tcgcatccgg tggtgagttg tcccgcatcg cattggcaat ccaggtcatt accgcgcgta
    21541 aaatggaaac cccagcactg atttttgatg aagtggatgt agggattagc ggcccaacag
    21601 cggcagttgt cggcaaactg ctacgtcaac ttggcgaatc aactcaggtg atgtgtgtta
    21661 cccacctgcc acaagtcgcg ggatatggtc atcaacacta ttttgtcagc aaagaaaccg
    21721 atggtgcgat gacagaaacg catatgcaat ccctggataa aaaagcgcgg ttacaagagt
    21781 tggcgcgcct gcttggtggc agtgaagtca cacgtaacac actggcgaat gcgaaagaac
    21841 tgcttgcggc gtaaactttt ttcctgcttc acggtcagag taaacagcaa aacgccgtaa
    21901 gaccggaaag caaaaggttt taaagtgatg aaaggtctat tatcatcggc atattacaga
    21961 tgagccacgt actgctcggg cccgaaaagg aatcaaatca ctatgcgctg taaaacgctg
    22021 actgctgcag cagcagtact attgatgttg accgcaggct gttccactct ggagcgagtg
    22081 gtttaccgtc ctgacatcaa ccaggggaac tatctgaccg ctaacgacgt atccaaaata
    22141 cgtgttggca tgacgcaaca acaagttgcg tacgcattgg gtacaccgct gatgtccgat
    22201 ccatttggta caaatacctg gttctatgtc ttccgccagc aacctggtca tgaaggtgta
    22261 acgcagcaaa cgctgacgct gacctttaac agtagcggtg tgttgaccaa cattgataac
    22321 aaacctgcgc tgagtggtaa ctaataataa agttgctctc aaagacgtta aaaaaggtgc
    22381 tcaatgagca ccttttttct gtctgttatt tattcgctga tttttctgct cgttgcctgc
    22441 gaagctcttt cggatcggca atgagaggac gataaatctc cacccgatcg ccatcatgca
    22501 caatatcgct gagttttgcc ggacggctgt aaatgccgac tttgttttta gttaaatcga
    22561 tatcggtacg caattccagc aaaccactgg cgcgaatagc ttcttcaacc gtcgcgccct
    22621 cctgcaacgt cacgcgctgc aggtactgct tctcaggtag cgcataagcc acctcaacgg
    22681 caattttacc tggcactgta gacctctttt gcacgaacag taaaagcctg caccatatta
    22741 gctgccagct ctttaaacac acgaccaaag gcgagttcaa tcaacttatt ggtaaactca
    22801 aagtcgagat gaaactcaat acggcacgcg tcctggctca acggcgtaaa cttccaaccg
    22861 cctatcaatt tcttaaacgg tccatcaacc agactcatga gaatactttg attactggtc
    22921 aactggttgc gggttgtaaa cgttttgctg atcccagcct tagacacatc taccgcagcg
    22981 gtcatctgcc caggagtgga ctccagaatc cggcttccag tgcaccctgg taaaaactga
    23041 ggataagact gaacgtcatt cactaactga tacatttgct ccgcgctgta gggtaccagt
    23101 gcggtccggc taatctgagg cataacaatt tccatcaaca aaaatccaac aaataatatc
    23161 atttatcctg ctgtaaaaaa aacgctatcc cggcgctggg taacatcggg atcatgctaa
    23221 gatagagcct tgtcccccgc aggattgata tggggtgttt tcgatttcag attaccgatg
    23281 attcacgacg cttatgacga agaaaaaagc acataaacct ggttcagcga ccatcgcgct
    23341 taacaagcgc gcccgtcacg aatactttat cgaagaagag ttcgaagcgg gacttgccct
    23401 gcaaggctgg gaggttaaat ccctgcgtgc aggaaaagcc aatatcagcg acagctacgt
    23461 ccttctgcgt gacggagagg catttctgtt tggcgctaac atcacgccaa tggctgtggc
    23521 ctccacgcat gtggtgtgcg atcctacccg tacccgcaag ttacttctca accagcgcga
    23581 actggactca ttgtacggtc gcgtaaatcg agaaggctat accgtagtgg cgctctccct
    23641 gtactggaaa aatgcctggt gcaaagtgaa aatcggcgtc gccaaaggta aaaaacagca
    23701 cgataaacgt tcagatatca aagaacgcga atggcaggtg gataaagcgc gtatcatgaa
    23761 aaacgcccat cgttaaacct atataagcga tactaatcaa atcctcaccg cgcctcccta
    23821 tccggtggcg cgaatgaaca tcttgtcgac tgtcaaatct gacacagatg tagccatccc
    23881 attgcttaat cgaaaaaaaa tcatactatg caggcgctaa ttccaggatg ataacgcctt
    23941 ttgggctagt catgctgctc ataaatctgg tatacttacc gttacacatt ggggctgatt
    24001 ctggattcga cgggatttgc gaaacccaag gtgcatgccg aggggcggtt ggcctcgtaa
    24061 aaagccgcaa aaaatagtcg caaacgacga aaactacgct ttagcagctt aataacctgc
    24121 ttagagccct ctctccctag cctccgctct taggacgggg atcaagagag gtcaaaccca
    24181 aaagagatcg cgtggaagcc ctgcctgggg ttgaagcgtt aaaacttaat caggctagtt
    24241 tgttagtggc gtgtccgtcc gcagctggca agcgaatgta aagactgact aagcatgtag
    24301 taccgaggat gtaggaattt cggacgcggg ttcaactccc gccagctcca ccaaataatg
    24361 attggacggt gtaaggacta caccaacaaa aacaggaagt tataagtctc agcaggacac
    24421 cgaccagacg gtgaggagac aaaaaaggat acgcaacgga gtcgcgactc cctatgacat
    24481 taaagcccgc tgatgcgggc ttttttattg gtcctgaccc gccctgaata gaattcatcc
    24541 aattacagtc cagacatata cagtatccct cagctcagta tcagcttctc gacaaatggt
    24601 cactgttatt tacccgtttc cagaaagaga ataatttgcc cccatagcca gccttcccgg
    24661 aatctgtatg ttcattaata ttgttatcga tgccatcaag taacataggt tggatgcgat
    24721 tgatcttact cacattagtc gacacggaac tcagtaagtt gaactctgaa aaagcagttt
    24781 aaatagcatt taaacaaatg ccaccagttc gaaaaagagt ataagcacac ttaatatatt
    24841 gttttaatta ttcatttcct ttcaacccaa ttcttatccc tcacattact tgttattaat
    24901 ttgctgtttt tgatcacaat aagaaaacaa tatgtaactt ttatgcgcat ttttcagaaa
    24961 tgtagatatt tttagattat ggctacgaaa tgagcatcgc catgtcaccc tacatctcat
    25021 aagaggatcg cttctgatga atgcactgac cgccgtacaa aataacgctg tcgattcagg
    25081 ccaggactat cgcggattca ctctcatccc gtcggcgcaa tccccgcgtc tgctggaact
    25141 caccttcacc gaacagacga ccaaacagtt tctcgaacag gttgccgaat ggcccgtgca
    25201 ggcgctggag tacaaatcgt ttctgcgttt tcaggtaggc aaaattctcg acgatctgtg
    25261 tgcgaatcag ctgcaaccgc tgctgttgaa gaccctgtta aaccgcgctg aaggtgcgct
    25321 gttgatcaat gcggtgggta tcgatgatgt cgcgcaggcg gatgagatgg tgaagctggc
    25381 gacggcggtg gcgcatctga ttggccgttc caatttcgat gccatgagcg gtcagtatta
    25441 cgcgcgtttc gtggtgaaaa atgttgataa ctcagacagc tatcttcgtc agccgcaccg
    25501 cgtaatggag ctgcacaacg acggcactta cgtcgaagag atcactgatt acgtgctgat
    25561 gatgaaaatc gacgagcaaa acatacaggg cggtaactcg ctgctgctgc atctcgatga
    25621 ctgggaacat ctggacctct ttttccgcca tccgctggcg cgccgtccga tgcgctttgc
    25681 cgcgccgccg agcaaaaacg tcagcaaaga tgtcttccat ccggtgttcg atgtcgatca
    25741 gcagggccgc ccagtgatgc gctatatcga ccagtttgtc cagccgaaag acttcgaaga
    25801 aggcgtgtgg ttgagcgagc tttcggacgc cattgaaacc agtaaaggca ctctttctgt
    25861 acccgttccc gttggcaaat tcctgttgat taacaacctg ttctggctgc acggtcgcga
    25921 ccgctttact ccgcacccgg atctgcgccg tgaactgatg cgtcagcgtg gctatttcgc
    25981 ttacgccact caccactacc agacgcatca gtaagcgcaa aggaattgag cggatgtatg
    26041 attttgtgat tattggcggc ggcatcatcg gcatgtcgac cgccatgcaa ctgattgata
    26101 tctatcctga cgcccgcatt gcgttgctgg aaaaagagtc cggccctgcc tgtcaccaga
    26161 cgggccacaa cagcggcgtg atccatgccg gagtctatta cacgcccggt agcctgaaga
    26221 cgcagttttg cctggcgggg aaccgcgcca ctaaagtctt ttgcgatcaa aacggcattc
    26281 gctacgacaa ctgcggcaag atgctggtcg ccacgtctga actcgaaatg gaacggatga
    26341 atgcgttatg gaaacgcacg gcggcaaacg ggatcgagcg cgagtggtta aacgccgagg
    26401 agctgcgcga gcgtgaaccg aatatcaccg ggcttggcgg catttttgtg ccgtccagcg
    26461 gcattgtcag ctaccgcgaa gtgacggcgg cgatggcaaa aatcttccag gccagaggtg
    26521 gtgagattat ttataacgcc gaagtcagcg ccctcagtga gcataaaaac ggcgtggtga
    26581 tacgtacccg tcagggcggt gaatatgaag catcgacgct gattagttgt tccgggctga
    26641 tggctgaccg gctggtgaaa atgctcggcc tcgaaccggg ctttattatc tgcccgttcc
    26701 gcggcgagta tttccgcctt gcgccagagc ataaccagat tgttaaccac ctgatttacc
    26761 ccattcccga cccggcaatg ccgtttttgg gcgtgcatct cacccgcatg atcgacggca
    26821 gcgtgaccgt cgggccaaac gcggtgctgg ctttcaaacg cgaaggctac cgcaagcgcg
    26881 acttctcatt tagtgacacg ctggagattt taggctcgtc ggggattcgc cgggtgctgc
    26941 aaaaccatct acgctcagga ctgggcgaga tgaaaaactc gctgtgcaaa agcggctatc
    27001 tgcggctggt gcaaaagtat tgtccccggc tttcgttaag cgatctccag ccctggcccc
    27061 ccggtgtgcg ggcgcaggcg gtatcgccgg acggcaagct gattgacgat tttctgtttg
    27121 tcaccacccc gcgcacgatc cacacctgta atgcgccctc cccggcagcg acatcagcaa
    27181 ttcctattgg tgcgcatatt gtcagcaagg tacaaacgct gttggcaagc cagagtaacc
    27241 ccggacgcac gctgcgagcg gcacgtagtg tggatgcctt acacgccgca tttaattaat
    27301 aacctttgaa aacaggatgt agcgatgaaa cttaacgaca gtaacttatt ccgccagcag
    27361 gcgttgatta acggggaatg gctggacgcc aacaatggcg aggtcatcga cgtcaccaat
    27421 ccggcgaacg gcgacaagct gggtagcgtg ccgaaaatgg gcgctgatga aacccgcgcc
    27481 gctatcgacg ccgccagccg cgccctgccc gcctggcgtg cgctcactgc caaagaacgc
    27541 gccaacattc tgcgcaactg gttcaattta atgatggagc atcaggacga tttagcgcgc
    27601 ctgatgaccc tcgaacaggg caaaccactg gctgaagcga aaggcgaaat cagctacgcc
    27661 gcctcattta ttgagtggtt tgctgaagaa ggcaaacgta tttatggcga caccattccc
    27721 ggtcatcagg ccgataaacg cctgattgtg atcaagcagc cgattggcgt caccgcggct
    27781 atcacgccat ggaacttccc ggcggcgatg attacccgta aagctggtcc ggcgctggcg
    27841 gctggctgca ccatggtgct gaagcccgcc agtcagacgc cgttctctgc gctggcgctg
    27901 gcagaactgg cgattcgcgc gggcgttccg gctggcgtgt ttaacgtggt caccggttcg
    27961 gcgggcgcgg tcggtaacga actgaccagc aacccgctgg tgcgcaagct gtcgtttacc
    28021 ggctcgaccg aaattggccg tcagttaatg gaacagtgcg cgaaagacat caaaaaagtg
    28081 tcgctggagc tgggcggcaa cgcaccgttt attgtctttg acgatgccga tctcgataaa
    28141 gccgtggaag gcgcgctggc ctcgaaattc cgtaacgccg ggcaaacctg cgtctgcgcc
    28201 aaccgcctgt atgtgcagga cagcgtgtat gaccgctttg ccgaaaaatt gcagcaggcg
    28261 gtgagcaaac tgcacatcgg cgacgggctg gagaaaggcg tcaccatcgg gccgttgatc
    28321 gatgaaaaag cggtagcaaa agtggaagag catattgctg atgcgctgga gaaaggcgcg
    28381 cgcgtggttt gcggcggtaa agcacatgaa cgcggcggta acttcttcca gccgaccatt
    28441 ctggtagacg ttccggctaa cgccaaagtg tcgaaagaag agacgtttgg ccccctcgcc
    28501 ccgctgttcc gttttaaaga tgaagccgat gtgattgcgc aagccaatga caccgaattt
    28561 ggacttgcag cctatttcta cgcccgtgat ttaagccgcg tcttccgcgt gggcgaagca
    28621 ctggagtacg gcatcatcgg catcaacacc ggcattattt ccaatgaagt ggccccgttc
    28681 ggcggcatta aagcctcggg tctgggtcgt gaaggttcga agtatggcat cgaagattac
    28741 ttagaaatca aatatatgtg catcggtctt taactggaga atgcgaatga tcagcaataa
    28801 agagttaatg cagcgccgca gtcaggcgat tccccgtggc gttgggcaaa ttcacccgat
    28861 tttcgctgac cgcgcggaaa actgccgggt gtgggacgtt gaaggccgtg agtatcttga
    28921 tttcgcgggc gggattgcgg tgctcaatac cgggcacctg catccgaaag tggttgcggc
    28981 ggtggaagcg caattgaaaa aactgtcgca cacctgcttc caggtgctgg cctacgagcc
    29041 gtatctggag ctgtgcgaga ttatgaatca gaaggtgccg ggcgattttg ccaagaaaac
    29101 tctgctggtt acgaccggtt ccgaagcggt ggaaaatgcg gtgaaaatcg cccgcgccgc
    29161 cactaaacgt agcggtacta tcgcctttag cggtgcgtat cacgggcgca cgcattacac
    29221 gctggcgctg accggcaagg tgaatccgta ctctgcgggc atggggctga tgccgggtca
    29281 tgtttatcgc gcgctttatc cttgcccgct gcacggcata agcgaggatg acgctatcgc
    29341 cagcatccac cggatcttca aaaatgacgc cgcgccggaa gatatcgccg ccatcgtgat
    29401 tgagcccgtt cagggcgaag gcggtttcta cgccgcgacg ccagccttta tgcagcgttt
    29461 acgcgcgctg tgtgacgagc acgggatcat gctgattgcc gatgaagtgc agagcggcgc
    29521 agggcgtacc ggcacgctgt ttgcgatgga gcaaatgggc gtggcaccag atctcaccac
    29581 ctttgcgaaa tcgatcgcag gcggtttccc gctggcgggc gtcaccgggc gcgcggaagt
    29641 gatggacgcc gtcgcaccgg gcggactggg tggcacctat gccggtaacc cgattgcctg
    29701 cgtagcggcg ctggaagtgt tgaaggtgtt cgagcaggaa aatctgctgc aaaaagccaa
    29761 cgttctgggg cagaagctga aagacggatt gctggcgata gccgaaaaac acccggagat
    29821 cggcgacgta cgcggtctgg gggcgatgat cgccatcgag ctgtttgaag atggcgatca
    29881 cagcaaaccg gacgcaaaac tcaccgccga gatcgtggca cgcgcccgcg ataagggtct
    29941 gattcttctc tcctgcggcc cgtattacaa cgtgctgcgc atccttgtac cgctcaccat
    30001 tgaagacgct cagatccgtc agggtctgga gatcatcagc cagtgttttg ctgaggcgaa
    30061 gctgtagcac cgcaccatgc cggaggcgac gctttgcggc ttgtccggcc tacgagaatc
    30121 caggtcggat aaggcgttta cgccgcatcc gacaatctgt acgtgaacag gaataaatct
    30181 atgtcggccg gataaggcgg agccgctctc cggcaaaaag aaccaataac aattaaacgc
    30241 gtgacccgac gcgggaaatg tcggggcgct ctcccaagtg acacactttc gagaggattc
    30301 aggatggggc aatcatcgca accacatgag ttaggcggcg ggctgaagtc acgccacgtc
    30361 accatgttgt ctattgccgg tgttatcggc gcaagtctgt ttgtcggttc cagcgtcgcc
    30421 atcgccgaag cgggcccggc ggtattactg gcctatctgt tcgccggatt actggtggtt
    30481 atgattatgc ggatgttggc ggaaatggcg gttgccacgc ccgataccgg ttcgttttcc
    30541 acctatgccg ataaagccat tggccgctgg gcgggctata ccatcggctg gttgtactgg
    30601 tggttttggg tactggttat cccacttgaa gccaacatcg ccgccatgat cctgcactca
    30661 tgggttccag gcattcccat ctggttattt tccctcgtca ttaccctcgc cttaaccggc
    30721 agtaatttat taagcgttaa aaactacggc gaatttgagt tctggctggc gctgtgtaaa
    30781 gtcatcgcta tcctggcctt tattttcctt ggtgccgtcg caattagcgg tttttacccg
    30841 tatgccgacg tgagcgggat ttcaagattg tgggatagcg gcggctttat gcccaacggc
    30901 ttcggtgcgg tattaagcgc gatgttgatc accatgttct cgtttatggg cgcagaaatt
    30961 gtcaccattg ccgccgcgga atccgacacg ccggaaaaac atattgttcg cgccaccaac
    31021 tcggttatct ggcgtatctc tattttctat ttgtgttcta tttttgtcgt tgttgcatta
    31081 atcccgtgga atatgccagg gctgaaagcc gttggttctt atcgctcggt tctggaattg
    31141 ctcaatattc ctcatgcgaa attaatcatg gactgcgtga tattactttc cgtaaccagt
    31201 tgcctgaact cggcgctgta taccgcttcc aggatgctct actccttaag ccgtcgcggt
    31261 gatgctcccg cggtaatggg taaaatcaac cgcagtaaaa ccccgtacgt agcggtgtta
    31321 ctctccacca gcgcggcatt cttaacggtg gtggtgaact attacgcgcc tgcgaaggtg
    31381 tttaaatttc tgatcgacag ctccggcgct atcgccctgc tggtttattt agtcatcgcc
    31441 gtttcacaat tgcggatgcg caaaattctg cgagcagaag gaagcgaaat tcgcctgcgg
    31501 atgtggcttt atccgtggct cacctggctg gtcatcggct ttattacctt tgtgttggta
    31561 gtgatgctat tccgcccggc gcaacagtta gaagtgatct ccaccggctt attagcgatt
    31621 gggattatct gtaccgtgcc aattatggct cgctggaaaa agctgataat gtggcaaaaa
    31681 acacccattc ataatacgcg ctgataatga tcaggagtca caccatgacc attacctctc
    31741 tggatggcta tcgctggctg aagaacgata ttattcgcgg caattttcag ccggatgaaa
    31801 aattacggat gagtttgctg acatcgcgtt atgcacttgg cgttgggccg ttgcgggaag
    31861 cactttcgca actggtggca gaacgactgg tcacggtggt gaatcaaaaa gggtatcggg
    31921 tggcgtctat gtcagagcag gagctgctcg atattttcga cgcccgcgcc aatatggaag
    31981 cgatgctggt gagtctggcg attgcccgcg gtggcgatga atgggaggca gacgttctcg
    32041 caaaagcgca tctgctcagt aagcttgagg cctgtgacgc cagtgagaaa atgcttgatg
    32101 agtgggatct gcgtcatcag gcgtttcata ctgcaattgt ggcgggctgt ggttcttact
    32161 atttgctgca aatgcgtgaa cggttgtttg atctggcagc gcgttatcga tttatctggc
    32221 tgcggcgaac agtgctttcg gtggaaatgc tggaagataa acacgatcag caccagaccc
    32281 tgactgcggc ggtactggcg cgagataccg cgcgcgccag tgagttaatg cgccagcatt
    32341 tactgacgcc aattcccatt atccagcagg cgatggctgg caattaacta ctcttcagga
    32401 atacgcaaca cttgccccgg gtaaatttta tccgggcttt ttagcatcgg tttattcgct
    32461 tcgaagattt tattgtacag attagcgtta ccgtagacct gtttggaaat ggcactcaga
    32521 gtgtcgccag acttaacggt ataaaactgg ctggcagtgg ctggtgtcgc cgttttcacc
    32581 tgatcatcga cactggcaat accggaaata ttccccaccg caacaaggat tttctccttc
    32641 gcctcctgac ttaagccgtc accagtgacc gtcgctttgc cgtcggcaat ttgaatgttc
    32701 actttatcgg catcaggtat accggttttg ttcagatgct cctgcacctt cttcgcctga
    32761 tcgtctttat cgtgctgacc tgtaaccgcg tcccagagtt tttctccggc atctttcaca
    32821 aaattgaaca gacccatagc tacctcattc gttaacggaa acactcagaa agtgtagcag
    32881 aggaacgcgg cgcgttaacg ccgcgggggt gagcacaggt ttaatcgcgg gtttgcaccc
    32941 agaacgcgtg aatcaaaccg gggatatagc caagcagtgt cagcagaata ttaataatga
    33001 acgcccaacc gaacccttta ccgagcagca cgccgagcgg cggcagaatg atggtgatga
    33061 cgattctcca gaaacccata tgtactccct ataagaaaat tactcattgt ttaaaaagag
    33121 attttatctc ttaagcgtag taattttagc ggagcctgcc agtttcagcg tacgctttta
    33181 ctctcattta cgctgctgat gctggtatat gttgcacact tagtttagag tttacttaat
    33241 ttagaaaata cttaaacaac tatgactgaa ctcgcacaat tacaggccag tgccgaacag
    33301 gcagcggcct tattgaaatc aatgagccac cctaaacgat tgctgattct gtgtatgctt
    33361 agcggttccc ccggcaccag cgcgggagag ctgacgcgca ttaccggact gagtgcctct
    33421 gcgacatcac agcatctcgc tcgtatgcgg ggcgaagggc ttatcgactg ccaacgggat
    33481 gcccaacgca ttctatattc cattaaaaat gaggcggtaa atgccattat cgccaccctg
    33541 aaaaatgtct attgtccgta aggagtcact atggctttga caaccatttc gccgcatgat
    33601 gcacaagaat taatcgcacg cggcgcaaag ttaatcgata ttcgtgatgc tgatgaatat
    33661 cttcgtgaac atattcctga agcagatctg gctccattat ccgtactgga acagtcaggt
    33721 cttccgccta aattacgtcg cgagcaaatt atattccact gccaggcagg taaacgcacc
    33781 agtaataacg ctgataaatt agcagcgatt gccgcccccg cagaaatctt tttactcgaa
    33841 gatgggattg atggctggaa aaaagcagga ttgccagtag cggtaaataa atcccaaccc
    33901 ttaccgttaa tgcgccaggt gcaaatcgcc gcgggtggtt taatattaat cggcgttgta
    33961 ctgggttata ccgtaaatag cgttttcttc ttattaagcg gctttgttgg tgctgggtta
    34021 ctgcttgcag gaattagtgg tttttgtgga atggcaaggt tgttagataa gatgccgtgg
    34081 aaccaacgag cttgagcagc gacgccggac gcgccatagc agcgacatcc ggcctcagta
    34141 attagatcag gaaatcgtcg agagatttac cttctgccag cgcctgagcg attggcttcg
    34201 gtgtacggcc ctgaccggtc caggttttag tttcaccgtt aacatcgatg aatttatatt
    34261 tcgccggacg cggctggcgt tttttaccag cgcgtggtgc cgcagcagag ctattaccca
    34321 ataactcttc cgggttaatt ccgtcagctt tcatcagctc cagccaggtg ctaatttttt
    34381 cctggcgctc tgccagttca cgctgctgtt gttcttcttc ttcacgtctt tctttagtga
    34441 caaccctgaa tttttcgagc atttcttcaa gaacgtcaat ggagaattcg cgagccatcg
    34501 cacggagggt gcgaatgtta tttaaacttt gtaacattac ggacataata aagaaaacct
    34561 tttaacgcca aaacaaaaaa gtatttcgtc gcgtagtgta agcgatcact tattatattt
    34621 ccacaaaatt taatctattt acagtcctgc acgagattat ttcagctgtt attttctgaa
    34681 actctcagaa taatttcaag attatatatt agccattttg atgagtaatt tcggttattg
    34741 gtgaacagag cggctctctc tgctcgctaa ttccgcaagc ctgacaaaac caaagtgaat
    34801 aaaaatgcaa ttcaaccgaa taaaagaaaa catctatcac tggtgctttc tgctgtcaat
    34861 gtacattatc tgtcataaaa aatgctgaaa atgacccggt cactacatac accgaattct
    34921 ctacgcttat agcgttacct cacccccaaa ccttcatgag tgaaaataaa ggcaagcaca
    34981 tatccaattg atttaattaa aaataaatca tatcggcatg taaaaatcca caatgtacaa
    35041 aaaacgcgcc gttacggaat attttatcta caaaaacaga ttaaatgaaa atttttcact
    35101 aattgattag tcatagccag cgatatacgc tatgcaaaaa tgcagatggc aatgagatcc
    35161 actgctttca tctccattaa catcccatta cgcttttatt aaggagcatt agcatgttct
    35221 caccgcagtc acgcttgcgt catgcagttg cagatacgtt cgcgatggtt gtttactgtt
    35281 ctgtcgtgaa catgtgtatt gaagttttcc tctccggaat gagcttcgaa cagtcttttt
    35341 attccagatt ggtagcgatt ccggtgaaca tcttaattgc atggccatac ggtatgtacc
    35401 gcgatctgtt tatgcgcgcg gcacgcaaag ttagcccgtc aggctggata aaaaatctgg
    35461 cggatatcct ggcttatgtg acgttccagt caccggtgta tgtggcgatc ttgttagtgg
    35521 tgggcgcaga ctggcatcag attatggcgg cagtcagttc aaacatcgtt gtttcgatgt
    35581 tgatgggggc ggtttatggc tacttcctcg attattgccg ccgactgttt aaagtcagcc
    35641 gttaccagca ggtaaaagcc tgacccttct tttcgcgact ggcatcgcca gtcgcgtctt
    35701 taactggctt cgccaaataa accattcaaa taacgttcaa gcgcaacacg cgaactaaag
    35761 ccatgcggga taccgtaatg ctcatgacgt tcacccgcta aatagagcgg aaattgctgg
    35821 taatgatcgc aagttttaat atcggaagcg ggttcagcca gtgttgaact acgttctttt
    35881 aatgttggat gaatcaccag ggcggtacgt cccattcgcg cttcgcgatt aacatagaca
    35941 taattttccc cacggcggta accatacgct ttctgggtta ccacatcgac agtaaaaccg
    36001 actttttcaa gtacgcgcgc cacctcgtct ggtcgtaaat acatatttga tcctcgttat
    36061 tatcaaccgc gggcctacct tacctgattg cgcattcaca acgctttcag aaaagtccat
    36121 aaagccgcga tgaacctcag ttaagaaaat tatggtctac actgaaaatt acatcgaatt
    36181 ctaatggggg atcatatgtt taaccgaccg aaccgcaacg acgttgatga tggcgtgcag
    36241 gatatccaga atgatgtcaa tcaattagct gacagtctcg aatctgtatt gaagtcctgg
    36301 ggcagcgacg ccaaagggga agccgaagcc gctcgtagta aagcgcaggc tctactgaaa
    36361 gaaaccaggg cgcgaatgca tggtcgtact cgcgtccagc aagccgcgcg cgatgccgtt
    36421 ggctgcgcgg attcttttgt tcgtgaaaga ccctggtgta gtgtgggtac agcggcagcg
    36481 gtgggtattt ttatcggcgc actgttaagc atgcgcaaat cgtagtgcaa aaatgataat
    36541 aaatacgcgt ctttgacccc gaagcctggc ttcggggttt ctttttgcct ggtgaatcac
    36601 aaaaatcccc ctaccccgtc acgctcgccc cagggtaacc ctgaccatta tttgctatat
    36661 attgtgtgat tgaatctttt ttcaactaca tctagtatct ctgtatcaac agagagacaa
    36721 cccgacgcgt atcatcgcgc cgtatcttca ttttaaacgg aaatacgaat catgcgcatt
    36781 actatttaca ctcgtaacga ttgcgttcag tgccacgcca ctaaacgggc gatggaaaac
    36841 cggggctttg attttgaaat gattaatgtc gatcgcgttc ctgaagcggc agaagcgctg
    36901 cgtgctcagg gctttcgtca gttgccggtt gtgattgcag gcgatcttag ctggtctggt
    36961 ttccgcccgg acatgatcaa tcgtctgcat ccagcgccac acgcggccag tgcatgagcc
    37021 agctcgtcta cttttccagc agctccgaaa atacgcagcg ttttatcgaa cgtttagggc
    37081 tgcccgcggt gcgcatcccg ctcaatgagc gggaacggat tcaggtagac gagccttaca
    37141 tcctgatcgt gccctcttac ggcggcggcg gtacggctgg cgcggtgcca cgacaggtca
    37201 ttcgcttttt aaacgacgag cataaccggg cgttgctgcg cggcgttatt gcttcgggta
    37261 atcgcaactt tggtgaggca tatggccgcg ccggagatgt gattgcccgg aaatgcggcg
    37321 tgccgtggct gtaccgcttt gaactcatgg gtacgcaaag cgatatcgaa aacgttcgta
    37381 aaggagtaac tgaattttgg caacgacaac cgcagaacgc ctgacgcagg aaacgatgga
    37441 ttatcacgct ctgaatgcga tgcttaacct ttacgatagc gcaggtcgca ttcagttcga
    37501 taaagatcgc caggcagtag acgcctttat gacgacgcat gtgcgtccga acagtgtggc
    37561 cttcagtagc cagcagcagc gcctgaactg gctggttaac gaaggttact atgatgaaag
    37621 tgtccttaat cgctactctc gcgattttgt cattacgctg tttgcccacg cgcacgccag
    37681 cggttttcgt ttccagacat tcctaggagc atggaagttt tacaccagct atacgttgaa
    37741 gacattcgac ggtaagcgtt atctggaaga ttttgccgat cgcgtcacga tggtggcgct
    37801 gacgctggca caaggcgatg aaacactggc gacgcagctc accgatgaga tgctgtcagg
    37861 acgctttcag ccagccacgc caacattcct caactgcggt aagcagcagc gcggcgaact
    37921 ggtttcctgt tttctgctgc gtattgaaga caatatggag tcgattggcc gggcagtaaa
    37981 ttccgcacta caactgtcga aacgcggcgg cggcgtagca tttttgctgt cgaatctgcg
    38041 ggaagcgggc gcgccaatta aacgtattga aaatcaatct tctggcgtga ttccggtgat
    38101 gaaaatgctg gaagacgcat tttcctatgc caaccaactc ggcgcgcgtc agggggctgg
    38161 ggcagtctat ttacatgctc atcatcccga tattctgcgt tttctcgata caaaacggga
    38221 aaatgccgac gaaaaaatcc gcattaaaac actgtcgctg ggcgtggtga tcccggatat
    38281 cactttccat ctggcaaaag agaatgcgca gatggcgctg ttttcgccct atgacgttga
    38341 gcgggtttat ggcaaaccgt ttgccgatgt cgccatcagc gaacgctatg acgaactggt
    38401 tgccgatgaa cgcattcgca aaaaatacct caacgctcgt gatttcttcc agcgactggc
    38461 agagatccag tttgagtctg gctatccgta catcatgtat gaagacacgg ttaaccgtgc
    38521 taaccctatc gccgggcgca taaatatgag caatctctgc tcagaaattt tgcaggttaa
    38581 cagcgcctca gaatatgacg agaatctcga ctatgcccgt acaggccatg atatttcctg
    38641 caatctaggg tcgttgaata ttgcccacac catggattcc cccgactttg cccgcacggt
    38701 agagactgcc gtacgcggtt taacggcggt gtcagatatg agtcatatcc gcagcgtgcc
    38761 gtccatcgaa gccggaaatg ccgcctcgca cgccatcgga ctggggcaga tgaatttaca
    38821 cggctatctg gcgcgagaag gcatcgctta tggttcgccg gaagcactcg atttcaccaa
    38881 tctctatttc tataccatca cttggcacgc actgcgtacc tcgatgttgc tggcgcgcga
    38941 acgcggtgaa accttcgccg ggttcaaaca gtcacgctat gccagtggtg aatatttcag
    39001 ccaatatctg caaagtaact ggcagccgaa aacggcgaaa gttggcgaac tgtttgcccg
    39061 tagcggtatt acgttaccta cccgtgagat gtgggcgcag ctgcgcgacg acgtgatgcg
    39121 ctatggtatc tacaaccaga atctccaggc ggtgccgcca accggttcta tctcttatat
    39181 caaccatgcc acgtcgagta ttcatccgat tgtggcgaaa gtagagatac gcaaagaggg
    39241 caaaaccggg cgcgtttact accctgcccc gtttatgact aacgaaaatc tggcgctgta
    39301 tcaggacgct tacgaaatcg gcgcagaaaa gatcatcgac acctacgcgg aagcgactcg
    39361 ccatgtcgat caggggctgt cgctgacgct gtttttcccc gataccgcca ccactcgcga
    39421 tatcaacaaa gcgcagattt acgcctggcg caagggtatc aaaacgctct attacattcg
    39481 cctgcgtcag atggcgctgg aaggcactga aattgaaggc tgcgtctcct gtgcacttta
    39541 aggaatatct atgaaactct cacgtatcag cgccatcaac tggaacaaga tatctgacga
    39601 taaagatctg gaggtgtgga atcgcctgac cagcaatttc tggctaccag aaaaggtgcc
    39661 actgtcgaac gatattcctg catggcagac attaagtgtc gtagaacaac aactaacaat
    39721 gcgcgttttt actggcctga cgctgctcga cacgctgcaa aatgttatcg gcgcgccctc
    39781 gctgatgccc gatgcactca ccccccatga agaggcggta ttatcaaata tcagctttat
    39841 ggaagcggtt catgcccgct cttacagttc aattttctcg acgctgtgcc agaccaaaga
    39901 tgtcgatgcc gcctacgcct ggagtgaaga aaacgcgccg ttgcagcgaa aagcacagat
    39961 tattcagcaa cattatcgcg gtgatgatcc gctgaaaaag aaaatcgcca gtgtgtttct
    40021 tgaatctttt ttgttctatt ccggtttctg gctgccgatg tatttttcca gccgcggaaa
    40081 gctaaccaat accgcagacc tgatccgtct gattatccgg gatgaagcag tccacggtta
    40141 ctacatcggc tataaatatc agaaaaacct ggaaaagatc tcccaggcac gacgtgaaga
    40201 attgaagagt ttcgccttcg atttgttgct ggaactctat gacaacgagt tgcaatacac
    40261 cgatgagctg tacgccgaaa ccccgtgggc tgacgatgtg aaagcgtttc tctgttacaa
    40321 cgccaataag gcgttgatga atctgggcta cgaaccgcta tttcccgcag aaatggcgga
    40381 agtgaatccg gcaatcctcg ccgcgctttc gccgaatgcc gatgaaaatc acgatttctt
    40441 ttccggttca ggctcttcat atgtgatggg aaaagcggtc gaaacagaag atgaagactg
    40501 gaatttctga gggggttatt ttcaaaaata tcactacccg ctgcagggaa ataattcccg
    40561 ccaaatagct ttatatcacg caaataattt gtggtgatct acactgatac tctgttgcat
    40621 tattcgcctg aaaccacaat attcaggcgt ttttttgcta tctttgacaa aaaatatcaa
    40681 cttttctcga tttgctctca gcccttatat catgggaaat tccggcgatt tgctcacatc
    40741 aatattcatg ccacatttgc catcaggggt tgcctcagat tctcagtatg ttagggtaga
    40801 aaaaagtgac tatttccatt gggtaatgta tcgacataaa caaataacag gaatctttct
    40861 attgcatggc aattaaatta gaaattaaaa atctttataa aatatttggt gagcatccac
    40921 agcgagcttt caaatatatc gaacaaggac tttcaaaaga acaaattctg gaaaaaactg
    40981 ggctatcgct tggcgtaaaa gacgccagtc tggccattga agaaggcgag atatttgtca
    41041 tcatgggatt atccggttcg ggtaaatcca caatggtacg ccttctcaat cgcctgattg
    41101 aacccacccg cgggcaagtg ctgattgatg gtgtggatat tgccaaaata tccgacgtcg
    41161 aactccgtga ggtgcgcaga aaaaagattg cgatggtctt ccagtccttt gccttaatgc
    41221 cgcatatgac cgtgctggac aatactgcgt tcggtatgga actggccgga attaatgccg
    41281 aagaacgccg ggaaaaagcc cttgatgcac tgcgtcaggt cgggctggaa aattatgccc
    41341 acagctaccc ggatgaactc tctggcggga tgcgtcaacg tgtgggatta gcccgcgcgt
    41401 tagcgattaa tccggatata ttattaatgg acgaagcctt ctcggcactc gatccattaa
    41461 ttcgcaccga gatgcaggat gagctggtaa aattacaggc gaaacatcag cgcaccattg
    41521 tctttatttc ccacgatctc gatgaagcta tgcgtattgg tgaccgaatt gccattatgc
    41581 aaaatggtga agtggtgcag gttggtacac cggatgaaat tcttaataat ccggcgaatg
    41641 attatgttcg taccttcttc cgtggcgtcg atattagcca ggtgttcagt gcgaaagata
    41701 ttgctcgtcg tacaccgaac ggcttaattc gtaaaacccc cggcttcggc ccgcgttcgg
    41761 cactgaaatt attgcaggat gaagatcgcg aatatggcta cgtcatcgaa cgcggtaata
    41821 agtttgtcgg cgctgtgtct atcgattcgc ttaaagccgc gttaacgcag cagcaaggtc
    41881 ttgatgcggc gctgattgat gcgccgttag cggtcgatgc acaaacgcct cttagcgagt
    41941 tgctctctca tgtcggacag gcaccctgtg cggtgcccgt ggtcgacgag gaccaacagt
    42001 atgtcggcat catttcgaaa ggaatgctgc tgcgcgcttt agatcgtgag ggggtaaata
    42061 atggctgatc aaaataatcc gtgggatacc acgccagcgg cggacagtgc tgcacaatcc
    42121 gcagacgcct ggggtacacc ggctgctgca ccgactgacg gcggtggtgc tgactggctg
    42181 accagtacgc ctgcgccaaa cgtcgagcat tttaatattc tcgatccgtt ccataaaact
    42241 ctgatcccgc tcgacagttg ggtcactgaa gggatcgact gggtcgttac ccattttcgt
    42301 cccgtctttc agggcgtgcg cgttccggtt gattacatcc tcaacggttt ccagcaattg
    42361 ctgctgggta tgcccgcgcc ggtggcgatt atcgttttcg ctctcatcgc ctggcagatt
    42421 tccggggtcg gaatgggcgt ggcgacgctg gtttcgctga ttgccatcgg cgcaatcggt
    42481 gcctggtcac aggcaatggt taccctggcg ctggtgttaa ccgccctgct gttctgtatc
    42541 gtcataggtt tgccgttggg gatctggctg gcgagaagtc cgcgagcggc gaaaattatt
    42601 cgtccactgc ttgatgccat gcagaccacg cccgcgtttg tttatctggt gccaatcgtc
    42661 atgctgtttg gtatcggcaa cgtgccgggc gtggtggtga cgatcatctt tgcactgccg
    42721 ccgattatcc gtctgacgat tctgggaatt aaccagattc cggcggatct gattgaagcc
    42781 tcgcgctcat tcggtgccag cccgagccag atgctgttca aagttcagtt accgctggcg
    42841 atgccaacca ttatggcggg cgttaaccag acgctgatgc tggccctttc tatggtggtc
    42901 atcgcttcga tgattgccgt cggcgggctg ggtcagatgg tacttcgcgg tatcggtcgt
    42961 ctggatatgg ggcttgccac cgttggcggc gtcgggattg tgatcctcgc cattatcctc
    43021 gatcgcctga cgcaggccgt tgggcgcgac tcacgtagtc gcggcaaccg tcgctggtac
    43081 accactggcc ctgtcggtct gctgacccgc ccattcatta agtaactctg cacttgcccg
    43141 gtaacaccgg gcatatcacc ctgccaaaaa aaggaataac aatgcgacat agcgtacttt
    43201 ttgcgacagc gtttgccacg cttatctcta cacaaacttt tgctgccgac ctgccgggca
    43261 aaggcattac agttaatcca gttcaaagca ccatcaccga agaaaccttc cagacgctgc
    43321 tggtcagccg cgcgctggag aaattaggtt ataccgtcaa taaacccagc gaagtggatt
    43381 acaacgttgg ctacacctcg cttgcttccg gcgatgcaac cttcaccgcc gtgaactgga
    43441 cgccactgca tgacaacatg tacgaagctg ccggtggcga taagaaattt tatcgtgaag
    43501 gggtatttgt taacggcgcg gcacaaggtt acctgatcga taagaaaacc gccgaccagt
    43561 ataaaattac caacatcgcg caacttaaag atccgaagat cgccaaactg ttcgatacca
    43621 acggcgacgg taaagcggat ttaaccggct gtaacccagg ctggggctgc gaaggtgcga
    43681 tcaaccacca gcttgccgcg tatggactga ccaataccgt gacgcataat caggggaact
    43741 acgcagcgat gatggctgac accatcagtc gttacaaaga gggtaagccg gtgttttact
    43801 acacctggac gccgtactgg gtgagtaacg aactgaaacc ggggaaagat gtggtctggt
    43861 tgcaggtgcc gttctccgca ctgccgggcg ataaaaatgc caataccaaa ctgccgaatg
    43921 gcgcgaatta cggcttcccg gtcagtacca tgcatatcgt tgccaacaaa gcctgggccg
    43981 agaaaaaccc ggcagcagcg aaactgtttg ccattatgca gttaccagtg gcagatatta
    44041 acgcccagaa cgccatcatg catgacggca aagcctcaga agacgatatt cagggccacg
    44101 ttgatggttg gatcaaagcc caccagcagc agttcgatgg ctgggtgaat gaagcgctgg
    44161 cagcgcagaa gtaattttta ttcgggcgga taaggcgttt ttgcctcatc cgccgctctg
    44221 tacacaatgc ctgatgcgac gctggcgcgt cttatcatac ctacaaacca caccgcacat
    44281 ttcaacaatc tatctttcat cccatattca tcaacatccg ctattattga tttccagctt
    44341 aatcatcacc tgatgaacaa aaataatgac taaacctaat catgagctta gcccggcgct
    44401 gatcgtgctg atgtctatcg ccaccggtct ggcggtagcc agtaactatt acgcccagcc
    44461 attgctcgac accatcgcgc gtaacttttc cctttccgcc agttcggcgg gctttattgt
    44521 taccgccgcg cagttgggct atgccgcagg tctgctgttt cttgttcccc tcggtgatat
    44581 gtttgaacgc cgccgcctga ttgtctcgat gaccttactg gcagcgggcg gtatgttaat
    44641 cactgccagc agtcagtcac tggcgatgat gatcctcggt acggcattaa ccggtttatt
    44701 ctcggtcgtg gcacaaattc tggttccact ggcagcgacg ctggcctcac cggacaaacg
    44761 cggcaaagtg gttggcacca ttatgagcgg cctgctattg gggatcttac tcgcacggac
    44821 cgttgccgga ttgctggcaa acctcggcgg ctggcgcacc gtcttttggg ttgcctcggt
    44881 gttaatggca ctgatggcgc tggcattatg gcgtggtctg ccacaaatga aatcagaaac
    44941 ccacctcaac tacccacagt tgcttggttc cgttttcagc atgtttatca gcgataagat
    45001 cctgcgcacc cgcgcgttgc tgggctgcct gacctttgcc aacttcagca ttctctggac
    45061 ctcaatggcc tttttgcttg ccgctccacc ttttaactac agcgatggtg taattggtct
    45121 gtttggactt gcgggagctg ccggagcgtt gggcgctcgt ccggcgggcg gttttgccga
    45181 caagggcaaa tcgcaccaca caacaacttt cggtctgctt ctgctgttac tttcatggct
    45241 ggcaatctgg tttggtcaca cttccgtact ggcgctgatt atcggcatcc tggtgctgga
    45301 cctcaccgtg cagggcgtgc atatcactaa ccagacggta atttatcgaa tacaccctga
    45361 tgcgcgtaat cgcctgaccg caggttacat gaccagctac tttattggcg gtgccgctgg
    45421 ttcgctaatt tcagcctcag cctggcaaca tggcagttgg gctggcgtgt gtctggctgg
    45481 cgcgacgatt gccctggtta acttactggt ctggtggcga ggttttcatc gtcaggaagc
    45541 cgcaaattaa gcaatcagca accgttttcg tggctttaca cttataaggg tgttaagaag
    45601 cccatcagtc tgataaggtt aagatattca ttcagtctat ttataatatt aacaatcgtt
    45661 aagcgtacac tctatggaaa gccctactcc acagcctgct cctggttcgg cgaccttcat
    45721 ggaaggatgc aaagacagtt taccgattgt tattagttat attccggtgg cctttgcgtt
    45781 cggtctgaat gcgacccgtc tgggattctc tcctctcgaa agcgtttttt tctcctgcat
    45841 catttatgca ggcgcgagcc agttcgtcat taccgcgatg ctggcagccg ggagtagttt
    45901 gtgggttgct gcactgaccg tcatggcaat ggatgttcgc catgttttgt atggcccgtc
    45961 actgcgtagc cgtattattc agcgtctgca aaaatcgaaa accgccctgt gggcgtttgg
    46021 cctgacggat gaggtttttg ccgccgcaac cgcaaaactg gtacgcaata atcgccgctg
    46081 gagcgaaaac tggatgatcg gcattgcctt cagttcatgg tcatcgtggg tatttggtac
    46141 ggtaataggg gcattctccg gcagcggctt gctgcaaggt tatcccgccg ttgaagcagc
    46201 attaggtttt atgcttccgg cactctttat gagtttcctg ctcgcctctt tccagcgcaa
    46261 acaatctctt tgcgttaccg cagcgttagt tggtgccctt gcaggcgtaa cgctattttc
    46321 tattcccgtc gccattctgg caggcattgt ctgtggctgc ctcactgcgt taatccaggc
    46381 attctggcaa ggagcgcccg atgagctatg aggttctgct gcttgggtta ctggttggcg
    46441 cggcgaatta ttgcttccgc tatctgccgc tgcgcctgcg tgtgggtaat gcccgcccaa
    46501 ccaaacgtgg cgcggtaggt attttgctcg acaccattgg catcgcctcg atatgcgctc
    46561 tgctggttgt ctctaccgca ccagaagtga tgcacgatac acgccgtttc gtgcccacac
    46621 tggtcggctt cgcggtactg ggtgccagtt tctataaaac acgcagcatt atcatcccaa
    46681 cactgcttag tgcgctggcc tatgggctcg cctggaaagt gatggcgatt atataatcca
    46741 caagaatcat ttttctaaaa caatacattt actttatttg tcactgtcgt tactatatcg
    46801 gctgaaatta atgaggtcat acccaaatgg atagttcgtt tacgcccatt gaacaaatgc
    46861 taaaatttcg cgccagccgc cacgaagatt ttccttatca ggagatcctt ctgacccgtc
    46921 tttgcatgca tatgcaaagc aagctgctgg aaaaccgcaa taaaatgctg aaggctcagg
    46981 ggattaacga gacgttgttt atggcgttga ttacgctgga gtctcaggaa aaccacagta
    47041 ttcagccttc tgaattgagt tgtgctcttg gatcatcccg taccaacgcg acgcgtattg
    47101 ccgatgaact ggaaaaacgc ggttggatcg aacgtcgtga aagcgataac gatcgccgct
    47161 gcctgcatct gcaattaacg gaaaaaggtc acgagttttt gcgcgaggtt ttaccgccgc
    47221 agcataactg cctgcatcaa ctctggtccg cgctcagcac aacagaaaaa gaccagctcg
    47281 agcaaatcac ccgcaaattg ctctcccgtc tcgaccagat ggaacagggc ggtgtggttc
    47341 tcgaagcgat gagctaacgc gtcatctcgc tcaaaaatcc agatttataa aagaaaaaat
    47401 aaccggccag catcgcaaca tgctggcctt tttggcaagc aggtcggctc agccgatgag
    47461 ttaagaagat cgtggagaac aatatgagcg caaatgcgga gactcaaacc ccgcagcaac
    47521 cggtaaagaa gagcggcaaa cgtaagcgtc tgctcctcct tctcaccttg ctctttataa
    47581 ttattgccgt agcgataggg atttattggt ttttggtact gcgtcatttc gaagaaaccg
    47641 atgacgcata cgtggcaggg aatcagattc aaattatgtc tcaggtgtct ggcagcgtga
    47701 cgaaagtctg ggccgataac accgattttg taaaagaagg cgacgtgctg gtcactctcg
    47761 acccgacaga tgctcgccag gcgtttgaaa aagccaaaac tgcactggct tccagcgttc
    47821 gccaaaccca ccagctgatg attaacagca aacagttgca ggcgaatatt gaggtgcaaa
    47881 aaatcgccct cgcgaaagca caaagcgact acaaccgccg tgtgccgctg ggcaatgcca
    47941 acctgattgg tcgcgaagag ctgcaacacg cccgcgacgc cgtcaccagt gcccaggcgc
    48001 aactggacgt cgctattcaa caatacaatg ccaatcaggc gatgattctg gggacgaaac
    48061 tggaagatca gcctgccgta caacaggctg ccaccgaagt acgtaacgcc tggctggcgc
    48121 tggagcgtac ccgtattgtc agtccgatga ccggttatgt ctcccgccgc gcggtacagc
    48181 ctggggcgca aattagccca acgacgccgc tgatggcggt cgttccagcc accaatatgt
    48241 gggtggatgc caactttaaa gagacgcaga ttgccaatat gcgtatcggt caaccggtca
    48301 ccatcaccac cgatatttac ggcgatgatg tgaaatacac cggtaaagtg gttggtctgg
    48361 atatgggcac aggtagcgcg ttctcactgc ttccggcgca aaacgccacc ggtaactgga
    48421 tcaaagtcgt tcagcgtctg cctgtgcgta ttgaactgga ccagaaacag ctggagcaat
    48481 acccgctgcg tatcggttta tccacgctgg tgagtgtcaa taccactaac cgtgacggtc
    48541 aggtactggc aaacaaagta cgttccacac cggtcgcggt aagcaccgcg cgtgaaatca
    48601 gcctggcacc tgtcaataaa ctgatcgacg atatcgtaaa agctaacgct ggctaatcca
    48661 gaggtgcgtg tgatgcaaca gcaaaaaccg ctggaaggcg cacaactggt cattatgacg
    48721 attgcgctgt cactggcgac attcatgcag gtgctggact ccaccattgc taacgtggcg
    48781 atccccacta tcgccgggaa tctgggctca tcgctcagcc agggaacgtg ggtaatcact
    48841 tctttcgggg tggcgaatgc catctcgatc ccgcttaccg gctggctggc aaagcgcgtc
    48901 ggggaagtga aactgttcct ctggtccacc atcgcctttg ctattgcgtc gtgggcgtgt
    48961 ggtgtctcca gcagcctgaa tatgctgatc ttcttccgcg tgattcaggg gattgtcgcc
    49021 gggccgttaa ttccgctttc gcaaagtcta ttgctgaata actacccgcc agccaaacgc
    49081 tcgatcgcgc tggcgttgtg gtcgatgacg gtgattgttg cgccaatttg cggcccgatc
    49141 ctcggcggtt atatcagtga taattaccac tggggctgga tattcttcat caacgtgccg
    49201 attggcgtgg cggtggtgtt gatgacactg caaactctgc gcggacatga aacccgcacc
    49261 gaacggcggc ggattgatgc cgtggggctg gcactgctgg ttattggtat cggcagcctg
    49321 cagattatgc tcgaccgcgg taaagagctg gactggttct catcacagga aattatcatc
    49381 ctcaccgtgg tggcggtggt ggctatctgc ttcctgattg tctgggagct gaccgacgat
    49441 aacccgatag tcgatctgtc gttgtttaag tcgcgcaact tcaccatcgg ctgcttgtgt
    49501 atcagcctcg cgtatatgct ctacttcggc gcgattgttc tgctgccgca gttgttgcag
    49561 gaggtctacg gttacacggc gacgtgggca gggctggcct ctgcgccggt agggattatt
    49621 ccggtgatcc tgtcgccgat tatcggccgc ttcgcgcata aactggatat gcgccgactg
    49681 gtaaccttca gctttattat gtatgccgtc tgcttctact ggcgtgccta tacctttgaa
    49741 ccgggtatgg attttggcgc gtcggcctgg ccacagttta tccagggttt tgcggtggcc
    49801 tgcttcttta tgccgctgac caccattacg ctgtccggtt tgccaccgga acgactggcg
    49861 gcggcatcga gcctctccaa ctttacgcga acgctggcgg ggtctatcgg cacgtcgata
    49921 accacgacca tgtggaccaa ccgcgagtcg ctgcaccatg cacagttgac tgagtcggta
    49981 aacccgttca acccgaatgc tcaggcgatg tacagtcaac tggaagggct tggtatgacg
    50041 caacagcagg catcaggctg gattgcccag cagataacca atcaggggct gattatttcc
    50101 gccaatgaga tcttctggat gtcagccggg atattcctcg tcctgctggg gctggtgtgg
    50161 tttgctaaac cgccatttgg cgcaggtggc ggcggaggcg gtgcgcacta aggttgccaa
    50221 agggagctgc ggctcccttt ttatttgctc attctgcaaa cggttgtttt atacactcat
    50281 tcggtgtatc ttttcgccgc cccaaactct tccattcacc attagccggt tctgagcatt
    50341 cgctcaggtt gttaattctc tttttccttc gccctcgctt tcgcgggtga tactcacatt
    50401 tttcttttaa ccccaaaact cgcaccctcg cgggcgtaca tttattacac acaaaataat
    50461 ggattattat gaatacccaa cgtaaatacg ggagaacctg gcattacccc ttctctccag
    50521 gcaccaccag cgatgaccgc attaacaccg attactggca ggatttacag accatcacgc
    50581 aattggtgca cacagaaaaa ctcgatggcg aaaataactg ccttaaccgc tacggcgtgt
    50641 ttgcccgctc ccatgccacg cctacgcagt cggcatggac ctataaaatt cgccaacgct
    50701 ggcaactgct gaaaaacgat ctcggcaacc tggagttgtt tggtgaaaat ctctacgccg
    50761 ttcattccat tgaataccgc gcgctggaac aggactttta cctgtttgcc gttcgctgcc
    50821 aggatatgtg gctgagctgg gaagaggtgc agttttacgc cgctctgttt gatttcccct
    50881 gcgttcccga aatctccggc ccgcagccgg ggaatgatga aaaaagctgg caacgtgatt
    50941 ttctggcgct gaccaatgcg cgcggcacat tcgatccctg ggatacgcaa acctgtcaac
    51001 cctgtacgct ggaaggcatt gtcagccgaa atcatgatgc gttttctgtc gctgactttt
    51061 cgcataacgt cttcaagtat gtgcgcaaaa atcatgtcaa aaccactgtg cactggaaac
    51121 gccactggca acgggcgcgg atggcccatg agttcgttta tggagaacag tcatgatttg
    51181 gcaacttacc gacgataaac gctggtcggc gctacgtcag cgttttagct gggttgagga
    51241 gatgcatcac acgccacaag accctgagca tcatggtgaa ggcgacgtcg gcgtacatac
    51301 cgaaatggtg cttaacgccc tcattactct gccagaattc cagcaactcc ccgctcaaca
    51361 gcaggaagtt ttatgggcgg cggcgttatt gcatgatgtt gaaaagcgca gcactaccgt
    51421 gcaggaaaac ggacgtattc agtctcctgg tcatgctcgt cggggcgaac tgacggctcg
    51481 acaaatttta tggcgcgata tcccaacgcc gttcgtgctg cgcgagcaaa ttgttgcact
    51541 ggtgcgtctg catgggttac cgctatggtt actggaacgt ccggaaccgg agcgtttgtt
    51601 gctcacggct gcaatgcgca tcgacacgcg tctgctcgct ttgcttgctc gtgccgatct
    51661 gcttggtcgc caaagcccgg atcagcaatc aatgctggaa cgcatcgatc tgttcgagct
    51721 gttttgccat gagcaacaat gctggggaaa aatgcgcccg ttcgtttctg attccgcacg
    51781 ctggcactac ctgactcatg agcaaagttc tcctgatttt gttccctggg aggctgaacc
    51841 ttttgaggtt attttgctgt gtggcttacc gggtatgggc aaagatcgct atatcagtga
    51901 acagtgccag ggaatggacg ttatcagcct tgatgatatg cggcggcgaa tcaatgccag
    51961 tccggacgac aaaaccgcca ccgggcgtat tgtgcaacag gcaaaagaag aggcgcgcgt
    52021 ttttttacgc cagaaaaagc cgttcatctg gaatgcaacg aacattaccc gccagctgcg
    52081 cagccagctc atcagtctgt ttacggctta cggcgcacga gtaaaaatcg tttatctgga
    52141 agtgccatgg gcgcaatgga accagcaaaa tgccagacgc gagtatgcag ttcctgaagc
    52201 ggtcgtgatg cggatggcct caaggctgga agttcctcaa cctgatgaag cacatagcgt
    52261 ggaatatcgg atgactgaca ggtaacaaaa gccgggcggt gttttcacca gcccggcctc
    52321 ttctgcttaa actgactaaa tgtgcagttc ctgcaacttc tctttcggca gcgccagttc
    52381 ttcgttgctg ttgatgcgca cgtcacgttc cagaatgtta cgcgcaatat cctgcgcttc
    52441 ctgcaacgag tgcatctggt aagtgccaca ctggtagacg ttcagttccg ggatctgatt
    52501 ctgatcctgc actttcagca cgtcttccat tgccgctttc caggcatcag cgacacgctg
    52561 ctcatctggc gtaccaatca gactcatata aaaaccggtg cggcagccca ttggcgagat
    52621 atcgataatc tctacgccat taccgttaag atggttacgc ataaaaccag caaacaggtg
    52681 ctccagggta tggatccctc tttctggcat cacttctttg ttcggcacgc agaagcgcag
    52741 atcgaacacg gtgattgcgt cgccatgcgg ggtgttcatt gttttcgcca cccgaactgc
    52801 aggcgcttcc atccgggtat gatcgactgt gaagctatct aacaacggca tttagccacc
    52861 tccggtaatt ttttttaaaa ttttctgaac tctttgttcc caggcgagtc tgagtatatg
    52921 aaagacgcgc atttgttatc atcatccctg aattcagaga tgaaattttg gccactcacg
    52981 agtggccttt ttcttttctg tcaggcgtgc ttttccagcc acaccgcaaa cggttcggta
    53041 tcagcggctt ccatttcctg ctgacggcgt tcagacgcct cgcgctcggc gacaaaatcc
    53101 tcttcgcgca gaatttccag cggctcttca cgcagcagat tacggtacgc ttcagcaaac
    53161 gctttgcctg ttccgccaat accagtatca atcatagacc ttaagatacg ggcagagaaa
    53221 gtcagatcgg gattatcgaa gcaggcgacc agttcatcac acactttctg atacgcttcg
    53281 ccgccgttaa tgctatccag cgtttgcgcg acgcgtttca gatcgcggaa cagatcttta
    53341 cccacctgcg gtaacgggaa ctgcgcggtt tcgcagccga tacccagcgt caggcccggt
    53401 ttgcgacctt cgaggatcac ccggttccag ttaacgcgtg tacaggcaag ttcgctactg
    53461 ctcatttccg gtgcgtcagc cagcgcacac cagaccataa acaggtcgag gaatcgcacc
    53521 tgttgttcat ctacaccaat cggcgagaac gggttgatgt ccagcgagcg gacttcaata
    53581 tattcaatgc cgccacgtaa cagcgcatca gaaggcgact caccactgcg ggtaacgcgt
    53641 tttggacgaa tcggcgcgta cagttcgttt tcaatctgca gcacattgct gttgatttgc
    53701 agccgcttac cgtctttctc aataccaatc ttcgcgtact cttccgatgg cgttttgatt
    53761 gcctgtttaa ggcccgccac gtactcgtag agatcattga aggtgatacc aagattgctt
    53821 tgcgatttat tggtatagcc gagatcgctc aaacgaagag aggtcgcata cggcaggtaa
    53881 tacataccgc actcggtttt ctcaaacggc agcgacgttg gttttccttg caagaaagaa
    53941 gaacaaatcg ctggagacgc accaaacaga taaggaatga cccaaccgaa gcgatagtag
    54001 ttacggataa cgcggaaata acccgcagaa attttctctt tggcatcagc gcccgagata
    54061 tcaccgcact tcgcctgcca gaatgccatt ggcaaagaga aattatagtg cacgccggaa
    54121 atggtttgca tcagcgcgcc gtagcgattt ttcagccctt cacggtacag cgttttaaag
    54181 cgaccggtgt tagaagtgcc gtactgtgcc agttcgatgt cctgaccttc tgcgatgtag
    54241 catggcatac ttaacggcca catccgctca tcgcccatat tgcgcgccgt atagcgatgc
    54301 agatcgcgca taaaggtcag catatgttca atatcaccat ccactggtgt aataaattcc
    54361 agcaatgctt ccgcaaaatc ggtagtaatc catttatggg tcagtgcaga acctaatgct
    54421 tcaggatgac ctgttgttgc cagtgtgcca tcagcattaa cacgcaaagt ttcgcgctcc
    54481 agcccacgct gtatcccctt taacgcctga ggatgttttt ccagccaggc cagcgcctgt
    54541 gatacgtccg ggatcaaatt gacctcccgc ctgtcaaaat cgttttaatt agcataactg
    54601 taatggtgac catatgtgca ggcctacaat tagtgccacc acatcatgcc ctgaacggta
    54661 gctgctgcaa ctgcaacata gcgtaacgct ttaccaaggc acaaaaaaaa gattaccggt
    54721 ccccacgaga tgcgcatcca tcccgctaac agacacagta aatcgccaac cacgggcatc
    54781 cagcttaata atagcgtgac tgcaccatag cgtttcagcc agccggtagc tttctcttgc
    54841 cagcgcgatg ttttacgcaa tggaaagaaa cgcccaagga taacgttagt taaccctcca
    54901 aggctattac ccattgttgc tgttaaaact aaaacccagg gatgactcac tccggaaagc
    54961 aacattgcca ccagcacgac ttcggagttg ccgggtaata gtgtagcgct gagaaaacta
    55021 ctggcaaaca acgagaaaag cgataacgct tcactcacag caagcgaaca tccacggcgt
    55081 ccatgcctgc tgcacgggcc gcctgaatac cgaaatcggc atcttcaaag accacacact
    55141 gcgtcggttg cacgcccata cgctgcgcgc acaacaaaaa tgtgtctggc gcgggtttat
    55201 ggtgtttgac gtgatcggca gcgacgacgg cgtcaaaata acggcgtaat cccaggtgcg
    55261 ccagcaatgc ctcagcgatg gcgctttcac tccccgttcc tacagccatt gggcgacgac
    55321 catgccagct tttcaccact tcaacaagag gaagcggctc gacactatcc agcagcatac
    55381 ttcttactgc ttctgttttt tcacgcgcta acgcatgcgg gtcgagatcg gcctgattca
    55441 gctcaataat cgcctgagca atacgccagg tgggcgagcc attaagcgca atcatcgcct
    55501 gaacatcgta ctgaagaccg tagtgcccta atacttcgcg ccacgcttta cggtgcgtag
    55561 gctcggtatc caggatggtg ccatccatat caaaaattaa acctgcataa cgctcgtaca
    55621 tggtcttctc gcaagtcgaa aaatatgacg ctactttagc gtaattgctt gattttgtcg
    55681 ctgatggaga aggagaagaa aattcaggaa atggataaag tagttattta gaaatgagat
    55741 atttttgaag gaaatttttt ggataatatg gtgcatccgg gaggatgact cactggcgtt
    55801 cgcccttcgg gccgctgctg gcgcaacgtt atcctccctg gtgcctgcgg ttaataccgc
    55861 tacctcttcg ataccttcat tgctgaaggt tacggagaat atggtgcatc cgggaggatt
    55921 cgaacctccg accgctcggt tcgtagccga gtactctatc cagctgagct acggatgcat
    55981 cgggaaaatt tattttactg ctgatattga tatcgctact aaagccatat caagtaagag
    56041 atggtgcatc cgggaggatt cgaacctccg accgctcggt tcgtagccga gtactctatc
    56101 cagctgagct acggatgcat cgggaaattt attttactgc tgatattgat accgccacta
    56161 aagccatatc aagtaagaga tggtgcatcc gggaggattc gaacctccga ccgctcggtt
    56221 cgtagccgag tactctatcc agctgagcta cggatgcatc gggaaactta ctttactgca
    56281 gattttttga taccgccact aaagccatat caagtaagag atggtgcatc cgggaggatt
    56341 cgaacctccg accgctcggt tcgtagccga gtactctatc cagctgagct acggatgcaa
    56401 atggcggtga ggcggggatt cgaaccccgg atgcagcttt tgaccgcata ctcccttagc
    56461 aggggagcgc cttcagcctc tcggccacct caccacacgc ctcttacgag tgcttcgaag
    56521 aacttgttta tcgctcatcg tcgctgcgtg gcgcacatat tactttctga gacttataag
    56581 tcaaacaatt tttcccacac ttttatcgtt tgcacacttc acgctcaatt agtctgtaaa
    56641 aacgtcaaaa agagtgtttt atcaacagaa aaacggaggt ctgacagata gcagtaatgc
    56701 aaaaaaatgg agacttaagt tgaatgaacg ggagtaaagc gaaaagacaa tggagtgaaa
    56761 gagaaatctt gagggtgcgt ctcaccgata aagatgagac gcggaaagat tagtaactgg
    56821 actgctggga tttttcagcc tggatacgct ggtagatctc ttcacggtga acagaaactt
    56881 ccttcggggc atttacgcca atacgtacct ggttgccctt tacccctaaa actgtcacgg
    56941 tgacctcatc cccaatcatg agggtctcac caactcgacg agtcagaatc agcattcttt
    57001 gctccttgaa agattaaaag agtcgggtct ctctgtatcc cggcattatc catcatataa
    57061 cgccaaaaag taagcaatga caaacacatt acatctaagc agtcatggca ttacattctg
    57121 ttaaacctaa gtttagccga tatacacaac ttcaacctga ctttatcgtt gtcgatagcg
    57181 ttaatgcgaa tgccgtgaag cgagtccacg gcattgcctg acgcttatat tattgcaatt
    57241 tcgcgctgac ccagcctttc acactggcta acgctgcagg taaggccgca gcatccgtac
    57301 caccggcttg cgccatgtca ggacgtccac cacccttgcc gcccacctgc tgagcgacca
    57361 taccaatcag ttcccctgct ttcacacgat ctgtgacgtc cttagatacg cctgcaatca
    57421 gagaaacctt accttcggct accgttgcca gcacgataat tgtcgacccc agctgatttt
    57481 ttaaatcgtc aaccatggta cgcaacattt tcggctcaac accgctaagc tcgctaacca
    57541 acagcttaac accattaaca tcaattgcct tactggaaag atttgcgctc tcctgtgcgg
    57601 cagcttgttc tttaagctgt tgtaactctt tttccagctg acgcgtacgt tccagtactg
    57661 aacgcacttt atcagccaga ttattgctat cgcctttcag cagatgcgcg acttcgctta
    57721 agcgatcgct gtctgcatga acggtggcga tagcgccttc tccggttacc gcttcgatac
    57781 gacgaacgcc tgcagcagta cccgattcag agatgatgcg gaacagacca atatcaccag
    57841 tgcggctggc gtgagtaccg ccacacaact cggtggagaa atcacccatg ctcagcacgc
    57901 gtacgcgctc atcatacttc tcgccaaaca gcgccatcgc acctttcgct ttcgccgctt
    57961 cgagatccat gatgttggtt tcgatcggca agttacggcg aatctgcgcg ttcaccaggt
    58021 cttcgaccgc acgaatctct tctggtttca tcgcttcgtt gtgtgagaag tcgaagcgca
    58081 gcactttgtc gttaaccagt gaacctttct gcgatacatg agtacccaga acctggcgca
    58141 gcgcagcgtg catcaggtgc gttgcggagt gattcagacg aatacgggcg cgacgagcct
    58201 catcaacatc agcctgcaca gcgtcgccca ctttcagaga acccacagca agtttaccga
    58261 tgtgaccaat cgcctggccg tatttctgcg tatcttccac cgcgaaggag aagttagcgc
    58321 ctttcagttc gcctttatca ccaacctgac cgccggattc cgcatagaat ggcgtttgat
    58381 ccagcacgac cacagcttcc tggcctgcat tgatggcatc aaccgattta ccatcaacaa
    58441 acagcgcagt cactttgccg ttcagttcca gatggtcata gcctttaaat tcagatgcac
    58501 tgtcaacacg gatcattgcg ttgtaatctg caccaaagcc gctggcttcg cgcgcacgac
    58561 gacgctgctc ttccattgct gcgtcaaaac cagcttcgtc aactttgatg ttgcgctcac
    58621 ggcaaacgtc agccgtcagg tcaaccggga agccgtaggt gtcgtacaga cggaaagcag
    58681 tttcaccatc cagcgtatca ccagaaagtt ttgccagctc ttcatccagc agcgccagac
    58741 cgcgctccag agtacgggca aactgctctt cttcagtctt cagcacctgc tcaacctgcg
    58801 cctgctggcg tttcaggtct tcacccgcag agcccataac gtcgattagc ggaccaacca
    58861 gtttgtagaa gaaggtttct ttcgcgccga gcatattacc gtgacgcact gcgcgacgaa
    58921 tgatacgacg cagtacataa ccacggtttt cattggacgg cattacgcca tccgcgatca
    58981 ggaacgcaca agaacgaatg tggtcagcga ttacgcgcag cgatttattg ctcagatcgg
    59041 tcgcgccagt gactttcgct accgcctgga tcaacgtgcg gaacaggtcg atgtcatagt
    59101 tagagttaac gtgttgcagc accgcagcaa tacgttccag acccataccg gtatctacag
    59161 acggtttcgg cagcggttcc atcgtgccat cggcctggcg gttgaactgc atgaagacga
    59221 tgttccagat ctcaatgtag cggtcgccgt cttcttccgg acttcccgga gggccgcccc
    59281 aaatgtggtc gccgtgatcg tagaagattt cggtgcacgg gccgcacgga ccagtgtcac
    59341 ccatctgcca gaagttgtca gatgcgtatg gcgcaccttt gttatcgccg atgcgaataa
    59401 tacgttcgcg cgggatccct acttcttttt cccagatttc gtaggcttcg tcgtcgcttt
    59461 catagacggt aacccacaga cgctctttcg gcagggcaaa ccatttttcg ctggtcagca
    59521 gttcccatgc aaactgaatg gcatcgtgtt tgaaatagtc gccgaagctg aagttgccca
    59581 gcatttcgaa gaaggtatgg tgacgcgcgg tgtaaccgac gttttccaga tcgttgtgtt
    59641 taccacccgc acgcacgcag cgttgggaag tggtagcgcg ggaataatta cgcttgtcga
    59701 gcccaaggaa cacatccttg aactggttca tcccggcgtt ggtaaacaac agagttgggt
    59761 cgttatgggg taccagggag ctgctggcaa ctacctgatg tcccttacta tggaaaaagt
    59821 cgagaaacgc ctgacggatc tcagcggtgc tcttgctcat aattatcctg aaatcaagct
    59881 aacgaaatat cgctaccagc cgttgcgtgt cgttaaccgc ccggctggta actgaaaagt
    59941 gggaataaga taagttttct tgactgggaa gtaaaatccc gtatgcgttc agtcggcaaa
    60001 atttcgccaa atatcctgga tatcttccat cagatagcca cgatagagca gaaaacgctg
    60061 gatcttaact ttttctgaaa agacagttgg caaaggttcg ccatattttc gcgtcgcctg
    60121 atcgcgcgcc agtgcgcacc agtcgatgtc acattcacgc atcgcttttt ctgtcgcttc
    60181 gcgggaaata cctttctgat tcagttcctg acaaatacgc gcaggtccat aacctttgcg
    60241 gctacggctg gcgataaagc gcgcaacaaa tcggctgtca tcaagatagc catgttcatg
    60301 gcaccaggca ataacgcgct cgtaatcttc tgccgtggca tcaatctctt ccgggccatt
    60361 tttgcccata atcggtgccg cgagtttacg tcgcagttct tgctcactgt gatcgcgcac
    60421 cgccagaatg cgtaccgcac gatccaacag gcgagcatat gccgggcgac gggatgttga
    60481 ttctgtcatg gcatatcctt acaacttaaa aaagcaaaag ggccgcagat gcgacccttg
    60541 tgtatcaaac aagacgatta aaaatcttcg ttagtttctg ctacgccttc gctgtcatct
    60601 acagagaaat ccggcgttga gttcgggttg ctcagcagca actcacgtac tttcttctcg
    60661 atctctttcg cggtttctgg gttatctttc agccaggcag tcgcattcgc tttaccctga
    60721 ccgatcttct cacctttgta gctgtaccac gcgcctgctt tctcgataag cttctctttc
    60781 acgcccaggt caaccagctc gccgtagaag ttgatacctt cgccgtagag gatctggaat
    60841 tcagcctgtt taaacggcgc agcgattttg ttcttcacca ctttcacgcg ggtttcgcta
    60901 cccaccacgt tttcgccctc tttcaccgcg ccgatacgac ggatgtcgag acgaacagag
    60961 gcgtagaatt tcagcgcgtt accaccggta gtggtttccg ggttaccgaa catcacacca
    61021 attttcatac ggatctggtt gatgaagatc agcagcgtgt tggactgctt caggttaccc
    61081 gccagcttac gcatcgcctg gctcatcata cgtgccgcaa ggcccatgtg agagtcgccg
    61141 atttcacctt cgatttccgc tttcggcgtc agtgccgcca cggagtcaac gacgataacg
    61201 tctactgcac cagaacgtgc cagggcgtca cagatttcca gtgcctgctc gccagtgtcc
    61261 ggctgggagc acagcaggtt gtcgatatcg acgcccagtt tacgtgcgta gattgggtcc
    61321 agcgcgtgtt cagcatcgat aaacgcacag gttttacctt cgcgctgcgc tgcggcgatc
    61381 acctgcaacg tcagcgtggt tttaccggaa gattctggtc cgtagatttc gacgatacgg
    61441 cccatcggca gaccacctgc cccaagcgcg atatccagtg aaagcgaacc ggtagagatg
    61501 gtttccacat ccatggaacg gtcttcaccc aggcgcatga tggagccttt accaaattgt
    61561 ttctcaatct ggcccagtgc tgccgccaac gctttctgtt tgttttcgtc gatagccatt
    61621 tttactcctg tcatgccggg taataccgga tagtcaatat gttctgttga agcaattata
    61681 ctgtatgctc atacagtatc aagtattttg tagaaattgt tgccacaagg tctgcaatgc
    61741 atacgcagta gcctgacgac gcaccgcatc acggtcaccg ctgaagcatt cccgccgggt
    61801 aatgccttca ccacgggcag tggcaaaagc aaaccagacg gtgccgacag gcttctcttc
    61861 actgccgcca tccggcccgg cgataccact aatagacacg gcgtaatcag cacgagccgc
    61921 tttcagtgcg cctatcgcca tttccaccac gacaggttcg ctcaccgcgc catgctgcgc
    61981 cagcgtctct tcgcgtacac cgatcatttg cgcttttgct tcgttactgt aggtgacaaa
    62041 tccgcgttca aaccaggcgg aactgccggc aatatcggta atcactttcg ctacccaacc
    62101 gccggtacaa gactcagcag ttgttacggt tgcgccacgg gctttcagcg ccagcccaac
    62161 ctgttcgctt aactgcatca gttcactttc agtcatcaca acctctgtca gtcaaaaatt
    62221 tatgccggac aagatagcac tttcccgcaa aagatgggga cgagcgattc attttacgag
    62281 tcgcgttccg aaaaaagact gttgcggcca gtcggtagag aaaaagcgct accatgccgc
    62341 gttcacattg atatgtattc acagggagag aatagcaatg gcaataaaga aaacggataa
    62401 caccccacaa aacgtgctca aacaaaccac acaaatgcgt atgtgggtca tcattggcgg
    62461 catcagcgca ctgatttccg tgatatgtaa agttttatct tctggctatc ttgaaccttt
    62521 tgacttcggt caggctgcgt taggcgttgt ctgcctggga tatgcgatat cgctgtcgaa
    62581 aaaaatcaag caattacgcc attcgaataa acagtaagat aacagaggga agtttaacct
    62641 ccctcttgca aatagttact gcacgcgcgc cagcgccacg gcctgtccta actgccagac
    62701 cgccattgcg taatgagtgc tgtggttata acgggtaata gtgtagaagt tcggcagacc
    62761 ataccagtac tggtaaccag tgccaacatc cagacgcagc aagctggcct gctgatgatt
    62821 ccccagcgac tgctgcggcg ttagtccagc tgcggcaagt tgtgaaatgc tgtacctggt
    62881 tttgaagcca ttcggtaagc ctggcgcctg accgtttgcc atcaccgcca cctgatcgcc
    62941 tttcacccag ccgtgcgctt tgaaatagtt cgctacacta ccgatggcat caaccggatc
    63001 ccacaggttg atatgcccgt caccgctgaa atccaccgca tattgtttgt aagacgatgg
    63061 cataaactga ccgtaaccca tcgcacctgc aaaggaacct ttcagattga gcggatcgtc
    63121 ctgctcgtcg cgcgccatca gcaggaaggt ttccagctca cctgaaaaat attccgcgcg
    63181 gcgagggtaa ttaaatgaca gcgttgccag cgcatcgaga atgcgagttt tccccatcac
    63241 gcgcccccag cgggtttcaa cgccgataat cccgacgata atttccggcg gtacaccata
    63301 cacctgccac gcgcgattca acgcatcttc atactgattc cagaaaacca caccgttctg
    63361 cacgttgtcc ggcgtaataa attttttgcg ataacgcagc catgcgccgt tcggacctga
    63421 tggcggtttc accgatgtgg ttggtgcctg gttatccatc agccgcagta ccgaatccag
    63481 acgtttcgcc tgggagagaa tttcctgcaa ctgctgacga tcgaaaccgt gtttgttcac
    63541 cattttgtcg atgaactgct gggcattcgg gttattggcg aagtcaccgc ccatctgcat
    63601 cacattgtgc tgcggctcaa gcaggaagcc gccagacggc gttccggtgg tcgtttcagt
    63661 ctcagtaggt tttggcttgc tgctacaggc ggcaagcaac acaaaaaggg gaagcaatgt
    63721 tacataacga cgcttgaaca tgaggggtcc atttaacaga ttcaaccagg ggcaagtatg
    63781 gtaaagcatc ccgccccgca caaggaagcg gtagtcactg cccgatacgg actttacata
    63841 actcaactca ttctcctcac taccttcttt atacaaactt tcaaaataaa atatttatct
    63901 ttcattttgc gatcaaaata acacttttaa atctttcaat ctgattagat tagattgccg
    63961 tttggtaata aaacaataaa tactgaagga gagaacaatg atagaaacca ttactcatgg
    64021 cgcagagtgg ttcatcgggc tgttccagaa aggcggagaa gtgtttaccg ggatggtaac
    64081 cggcattctt ccgctgttaa ttagcctgct ggttatcatg aacgcattga ttaattttat
    64141 cggtcagcat cgtattgaac gatttgctca acgttgcgcc ggtaaccctg tttcccgtta
    64201 tctgctgcta ccgtgcattg gtacgtttgt cttttgtaac ccgatgaccc taagcctggg
    64261 tcgctttatg ccggaaaagt acaaacccag ctattacgcg gcggcctctt atagctgcca
    64321 ctcaatgaat ggcctcttcc cccatatcaa ccctggcgaa ctgtttgttt atctcggcat
    64381 tgccagcggt ctgacgacgc tgaatctgcc acttggccca ctggcggtga gctatctgct
    64441 ggttggtctg gtcaccaact tcttccgcgg ctgggtaacc gatctgacca ccgccatttt
    64501 cgagaaaaag atgggcattc aacttgaaca aaaagttcgt ctggcaggag caacatcatg
    64561 acacgcattc ggatcgaaaa aggaacgggt ggctggggcg gcccgcttga gctggaagcc
    64621 acgccgggca aaaaaatcgt ctatatcacc gccggtaccc ggcctgcgat tgttgacaaa
    64681 ctggcacagc ttactggctg gcaggctatt gacggattta aagaaggtga acccgcggag
    64741 gcggaaattg gtgtcgcggt aatcgactgt ggcggcacat tacgctgcgg catctatccg
    64801 aaacggcgta ttcccaccat taatatccac tcgacgggca agtctggccc gctggcgcag
    64861 tacattgtgg aagatattta tgtctctggc gtaaaagaag aaaacatcac tgtagtgggt
    64921 gaggcgacac cacaaccctc ttccgtgggc cgtgactatg acaccagcaa gaaaatcacc
    64981 gaacaaagcg atggtttact ggcgaaggtg ggaatgggta tgggttctgc cgttgccgtg
    65041 ttgtttcaat ctggtcgtga caccatcgac actgtattaa aaaccattct gccgtttatg
    65101 gcgttcgtct cggcgcttat cggcatcatt atggcttccg gtcttggcga ctggattgcc
    65161 cacggtcttg ctccgctggc gagccatcca ctgggtctgg tcatgctggc gctcatctgc
    65221 tccttcccgc tgctttcacc tttcctcggc ccaggcgcag ttatcgcaca ggttatcggc
    65281 gtattgattg gcgtgcagat tggtctcggc aatattccgc cgcatctggc tttaccggca
    65341 ctgtttgcca tcaacgcgca ggcggcctgc gacttcatcc cggtcggttt gtcgctggcg
    65401 gaagctcgtc aggacacggt tcgcgtcggt gtcccttctg ttctggtgag ccgcttttta
    65461 accggcgcgc caactgtact gatcgcctgg tttgtctccg gttttatcta tcaatagagg
    65521 ctgaaacatg accgttattt atcagaccac catcacccgt attggcgcga gtgccactga
    65581 cgccctcagc gaccagatgc tcatcacctt tcgtgaaggc gcgccagcgg atctcgaaga
    65641 gtattgcttc attcattgcc acggcgagtt gaaaggtgca ctccatcccg gtttgcaatt
    65701 tacgctcggg cggcatcgct atccggtgac cgccgttggc agcgtggcgg aagacaacct
    65761 tcgcgaactg ggtcatgtca ccctgcgctt cgatggttta agcgaagcgg aatttccggg
    65821 cactgtccat gtggcaggcc ctgtacccga cgatatcgcg ccgggatcgg ttttgaagtt
    65881 tgaatctgtt aaggagtaaa aaatgaatca ggttgccgtt gtcatcggtg gtgggcaaac
    65941 cttaggcgcg ttcctgtgcc acggtctggc tgccgagggg tatcgcgtgg cggttgtcga
    66001 tattcagagc gacaaagccg caaatgtggc acaagaaatt aacgccgaat atggtgaagg
    66061 aacagcgtac ggttttggtg ctgacgccac cagcgagcaa agcgttctgg cgctttctcg
    66121 tggggtagat gaaatctttg gtcgcgtgga tttgctggtc tacagcgccg gaatagcaaa
    66181 agcagccttt atcagcgatt tccagcttgg agattttgac cgttcgctac aggtgaatct
    66241 ggtgggttat ttcctgtgtg cccgtgaatt ttcgcgtttg atgattcgcg acgggattca
    66301 gggtcgcatt attcagatca actcgaaatc cggcaaagtg ggcagcaaac acaactctgg
    66361 ctacagcgca gcgaaatttg gtggcgtcgg gctgactcaa tcactggcgc tggatctggc
    66421 ggagtacggc attacggtgc attcgctgat gctcggtaac ctgctgaaat cgcctatgtt
    66481 ccagtcactg ttgccacaat acgcgaccaa gctgggtatc aaaccggagc aagtcgagca
    66541 gtattacatc gataaagtac cgctcaaacg cggctgcgat tatcaggatg tgctgaatat
    66601 gctgctgttc tacgccagtc ctaaggcgtc gtactgcact ggtcagtcga tcaatgtcac
    66661 cggcggtcag gtgatgttct gatcaacagc ggagatcttt taaggatctc cgcgcgacta
    66721 atagaatgcc tgatgcgcta cgcttatcag gcctacagga cttccgccac tacatcacgg
    66781 agaagttatg gtatccgcac tcatcaccgt cgccgttatc gcctggtgtg cgcaactggc
    66841 cttaggcggt tggcaaattt ctcgttttaa ccgtgccttc gacacactat gccaacaagg
    66901 gcgcgttggc gtgggacgtt ccagcgggcg ctttaaacca cgggtcgtgg tcgccatcgc
    66961 gctggacgat cagcagcgca tcgtcgacac cttgtttatg aaaggactga ccgtcttcgc
    67021 ccgaccgcaa aaaattcccg caattaccgg catgcatgcg ggtgatttac agcccgatgt
    67081 gatctttccc catgatccac tatcacagaa tgctctatca ttggcgctta aactgaaacg
    67141 tggataattt cgttgtgaat gttactagct tgcgaagtta tcattttgaa acctaaatca
    67201 ggtaatcacg cccatgaaac ctcgtcagcg tcaggccgcc attctggagt atctgcaaaa
    67261 gcagggtaaa tgctcggttg aagaattggc gcaatacttt gacaccacag gcacaaccat
    67321 tcgcaaagat ctggtcattc tggaacatgc cggaaccgtc attcgtactt atggcggcgt
    67381 ggtgttgaac aaagaggaat ccgatccgcc tatcgatcat aaaacgctta tcaacaccca
    67441 caagaaagag ctgattgcag aagctgccgt tggttttatt catgatggcg actcaataat
    67501 tcttgatgct ggcagtaccg tgttgcagat ggtgcctctg ctctcacgtt ttaataacat
    67561 cacggtgatg accaacagtc tgcacatcgt caatgcgcta tccgaactgg ataacgaaca
    67621 aactatcctg atgccaggcg gaacatttcg taaaaaatcg gcctcatttc acgggcaact
    67681 ggcagagaat gccttcgagc atttcacctt cgataaattg tttatgggca ccgacggcat
    67741 cgatctcaat gcgggcgtaa ccacgttcaa cgaggtttat accgtcagta aggcgatgtg
    67801 caatgccgcg cgcgaagtga ttttgatggc tgactcatcg aagtttggtc gtaaaagccc
    67861 caacgtggtt tgtagtcttg aaagcgtcga taagctgatt accgacgcag gtatcgatcc
    67921 agcgtttcgt caggcgctgg aagaaaaagg gatcgacgtg atcataaccg gagagagcaa
    67981 tgagtgaagc actactgaac gcgggacgtc agacgttaat gctggagttg caggaagcaa
    68041 gtcatttacc ggaacgtctg ggcgatgatt tcgttcgcgc cgccaatatc atcctgcact
    68101 gcgaaggcaa agtggtggtt tcgggaattg gcaaatcggg ccacattggt aagaaaatcg
    68161 ccgcaacgct tgccagcacc ggcacaccgg ctttttttgt ccatccggca gaagcactgc
    68221 acggcgatct ggggatgatt gaaagccgcg atgtgatgct gtttatctct tattccggtg
    68281 gcgcgaagga actggatctc attattccgc gtctggaaga caaatctatc gcgctgctgg
    68341 caatgaccgg aaaaccgacg tcaccgctgg gcctggcggc gaaagcggtg ctggatatct
    68401 ccgtagaacg cgaagcctgc ccgatgcacc ttgcgccgac ctccagcacc gtgaataccc
    68461 tgatgatggg cgacgcgctg gcgatggcag tcatgcaggc gcgtggtttt aatgaagaag
    68521 attttgcacg ctcccaccca gccggggcac tgggcgctcg cttgctgaac aaagtgcatc
    68581 atcttatgcg tcgtgacgat gccatcccgc aggtagcgtt aaccgccagc gtgatggacg
    68641 cgatgctgga acttagccgc accggtttag gtctggtggc agtgtgcgat gatcaacgac
    68701 tggtgaaagg cgtctttacc gacggtgatt tacgtcgctg gctggttggc ggcggcgcac
    68761 tcaccacgcc agtcaatgaa gcgatgacgg tcgacggcac cacgttgcaa tcgcaaagcc
    68821 gtgccatcga cgccaaagaa atcctgatga aacgaaaaat caccgccgca ccggtagtgg
    68881 atgaaaacgg caaactcacc ggcgcaatta acctgcagga tttctatcag gccgggatta
    68941 tttaatcctt cagccccaga cgtttcgcca gccgatgcag gttggcgacg tcggtttcca
    69001 gcatccgcgc acaggcggcc cagttgtgat gattttgcgc cagtgcctga cgaatggttt
    69061 cacgctggaa cgcttctgtc gcttcacgca gattttgctt aacaacgggc accgccgccg
    69121 cttctggcgg cggcaacgtc acctcaggaa aagcaaaatg ttgcgcctca agaatcactt
    69181 catcgccgct gcgggtggct ctcgacaata ctaccgcccg atgaatagca tgttccagtt
    69241 cgcgcacgtt tcccggaaaa ttgtagtgtt gcagtaaatt tcgcgctccg gcacttaata
    69301 ccacgcggga gagccccagc cgcaaacgac actgctcgca gaaatacccc gccagcagaa
    69361 tgacatcatc gccccgctca cgcagcggcg gcactgaaag tggaaacacg ctcaggcggt
    69421 ggaacaagtc agcgcgaaat cgccctgcca gtacctcttc gcgtaagtca cggttagtcg
    69481 ccgccagcac gcgcacatcg acccgcaaac tgcggtcatc gccaacgcgt tgaatatcgc
    69541 catactgcaa caccctcagc agcttggcct gcaatgccaa cgacaactcg ccgatctcat
    69601 cgagaaacag cgtgccgtta tccgccattt caaacttccc gctgcggtta ctgatagcac
    69661 cagtaaacgc ccctttcaca tgcccgaaca actcactttc cgccacactt tccggcagtg
    69721 cggcacagtt gagatagacc agcggattca ccgcccgtgg cgaggcttca tgaatcgctt
    69781 tcgccaccag ctccttaccg gttcccgtct caccgctaat taaaacgttg agatcggatg
    69841 ccgccacaat ctcaatctct tttttcaatt gcgtcatgcc tggggacaaa ccaatcatct
    69901 gcgtctgttt caccgcttca aacggcgcgg catcgcctgg cagcatattc tggctttcca
    69961 gttgttcaat cagtaacgca ttgcttaacg ctcccgccgc cagcgcagca atcaggcgta
    70021 actcttcgtc gctgaaaaca tcgaactgat cgggctgcat cccgtcgagc gtcaaggcac
    70081 cgatcaggtt ttgcccggca aacaacggca aaccaacgca ggcgtgaacc ttcagactct
    70141 cctgccctgg aatcagaccg tcataaggat cgggcaattc gctgtctgcg ggaaagcgca
    70201 ccacatcacc cgcgcgggca atcgcttcca gccgtggatg cccttccagc gcaaagcgtc
    70261 taccgagtac atccttcgcc agcccgtcga tggcaagcgg aataaactgc cgcgagtcgt
    70321 aacgtagcaa cgcagacgca tcgcactcca gcacctgacg cagcgtagtg atcaggcgct
    70381 gaaaacgatc ctgatgacca atcccacgct gcaattcgat ggcgatattc gccagcacat
    70441 caacggaaaa actcatcttt gcctcactgt caatttgact atagatattg tcatatcgac
    70501 catttgattg atagtcattt tgactactca ttaatgagca taattttatt tatagagtaa
    70561 aaacaattag ataaaaaact ggcacgcaat ctgcaatcag caagacatct ttttagaaca
    70621 cgctgaataa attgaggttg ctatgtctat tgtggtgaaa aataacattc attgggttgg
    70681 tcaacgtgac tgggaagtgc gtgattttca cggtacagaa tataaaacgc tgcgcggcag
    70741 cagctacaac agctacctca tccgcgaaga aaaaaacgtg ctgatcgaca ccgtcgacca
    70801 taaattcagc cgcgaatttg tgcagaacct gcgtaatgaa atcgatctgg cggatatcga
    70861 ttacatcgtg attaatcatg cagaagaaga ccacgccgga gcgctgaccg aactgatggc
    70921 gcaaattccc gatacgccga tctactgtac agccaacgct atcgactcga taaatggtca
    70981 tcaccatcat ccggagtgga attttaatgt agtgaaaact ggcgacacac tggatatcgg
    71041 caacggcaaa caactcattt ttgtcgaaac gccaatgctg cactggccgg acagcatgat
    71101 gacttacctg acaggcgacg cggtgctgtt cagtaacgat gctttcggtc agcactactg
    71161 cgacgagcat ctgttcaacg atgaagtgga tcagactgag cttttcgagc agtgccagcg
    71221 ttactacgcc aatatcctga cgccgttcag ccgcctggta acgccgaaaa ttaccgagat
    71281 cctgggcttt aacttgccag tcgatatgat agcgacctct cacggcgtgg tatggcgcga
    71341 taacccgacg caaattgtcg agctgtacct gaaatgggcg gcggattatc aggaagacag
    71401 aatcaccatt ttctacgaca ccatgtcgaa taacacccgc atgatggctg acgctatcgc
    71461 ccaggggatt gcggaaaccg acccacgcgt ggcggtgaaa attttcaacg tcgcccgaag
    71521 cgataaaaac gaaatcctga ccaatgtctt ccgctcaaaa ggcgtactgg tcggcacttc
    71581 tacgatgaat aatgtgatga tgccgaaaat cgccgggctg gtggaggaga tgaccggatt
    71641 acgcttccgt aacaaacgcg ccagcgcttt cggctctcac ggctggagtg gcggtgcggt
    71701 ggatcgtctt tccacgcgcc tgcaggatgc gggtttcgaa atgtcgctta gcctgaaagc
    71761 caaatggcga ccagaccagg acgctctgga gttatgtcgt gaacacggtc gcgaaatcgc
    71821 ccgtcagtgg gcgctcgcgc cgctgccaca gagcacggtg aatacggtgg ttaaagaaga
    71881 aacctctgcc gccacgacgg ctgacctcgg cccacggatg caatgcagcg tctgccagtg
    71941 gatttacgat ccggcaaaag gcgagccaat gcaggacgtt gcgccaggaa cgccgtggag
    72001 tgaagtcccg gataacttcc tgtgcccgga atgctctctc ggcaaagatg tctttgacga
    72061 actggcatcg gaggcaaaat gagcaacggc attgtgatca ttggttcggg cttcgccgcc
    72121 cgccaactgg tgaaaaatat tcgcaaacag gacgcctgta ttccattaac cctgattgcc
    72181 gccgacagca tggatgagta caacaaacct gacctcagcc atgttatcag tcaggggcaa
    72241 cgtgccgacg accttacccg ccagacggca ggtgaatttg ccgagcagtt taatctgcgc
    72301 ctgtttccgc acacctgggt aacggatatc gatgccgaag cccatgtggt gaaaagtcag
    72361 aataatcagt ggcaatacga caagttagtg ctggcaaccg gtgccagcgc ctttgtcccg
    72421 ccagtgcccg ggcgtgagtt aatgctgacg ttaaatagtc agcaagagta tcgcgcctgt
    72481 gaaacacaac tgcgggatgc ccgacgcgtg ttgattgttg gcggtggttt gattggtagc
    72541 gaactggcga tggatttttg tcgggcaggc aaagcggtca cgctaatcga caacgctgcc
    72601 agtattctgg cgtcgttaat gccaccggaa gtcagcagcc gcttgcagca tcggttgacg
    72661 gagatgggcg ttcatctgct gttaaaatct cagttgcaag gactggaaaa aacagattct
    72721 ggcattctgg caacgctgga ccgccagcgc tgcatcgaag tggatgcggt aattgccgcc
    72781 accggactgc gcccggaaac cgccctggca cgacgcgccg ggctgacgat taatcgcggc
    72841 gtttgcgtcg atagttatct gcaaaccagt aatgccgata tttatgcgct gggcgattgc
    72901 gcggaaatta acggtcaggt attgccgttc ctccagccga ttcaacttag cgcgatggtg
    72961 ctggcaaaaa atcttctcgg caataacacg ccgctgaaac tcccggcgat gctggtgaaa
    73021 atcaaaacgc cggaattacc gctgcatctg gcaggcgaac cccagcgtca ggatttacgc
    73081 tggcaaatta ataccgaacg ccagggaatg gtggcgcgcg gtgttgacga tgctgaccag
    73141 cttcgcgcct ttgtggtcag tgaggatcgg atgaaagagg catttggatt gttgaaaacg
    73201 ttgtcgatgt aggcgagcta cagtgcccca aatgtcggat gcggcgctga cgcgtcttat
    73261 ccgacctaca gggaacgcat gtgttgatca cataatacgt ttatgtcgca ttgcactgtc
    73321 ccaaaatgtc ggatgcgacg ctagcgcgtc ttatccgacc tgcggggatg aatatgtagg
    73381 ccggataagg cgttcacgcc gcatccggca atggtgtcca aatgcaacac gctttatccg
    73441 ttctggactt cacccgctaa ccaacgcgcc gcagcaataa ccccctgccc cagagacaac
    73501 ccgccatcgc ccgcaggtaa actctgtgga aagagcaatg tgaaatcagc gagataatgc
    73561 gccagacgtg cacgcagcaa acggttatga ataaccccgc cgctaaatac cagcgtagtg
    73621 ataccacgca tcgtggcctg ctcacgcatc aacgcggccc ccccctgcgc cagcgcatca
    73681 tgaaacgccc acgcacgttg attaaccgga gcctgccagt tcagccactg ctgccagaag
    73741 gtggcgagat ccagttgatt atccaccagc ggcatcgtca ccggatgcgt cacgccgtgg
    73801 cacgaagtcg ccagcgcctc cagagcacaa gccgcttcac cttcataact taacgtggct
    73861 ggcgcacagc ccagcgccgc cgctacggca tcgaacaacc gcccacacga tgacgccagt
    73921 ggtgcattga ttccacgctc aatggcccgc gccagcacgc tccagttttg ctgttgcaca
    73981 cttaccgttt cgggataact ctgccactcc ggcacaaaac gcaagcactg cgtcagcagg
    74041 tttcgccacg gctgctttgc ggcaagatcg ccaccagcaa gcgccactgc aggcaagccg
    74101 cccaggtgct cgcattcacg atagttcacc cgcaggcact ctccccccca caaagcgccg
    74161 ttctccccca taccaatacc gtcgagtgtc aacgcaatga catctccgcc atccagcggc
    74221 cagtgatgtt ctgccagaca tgccgctgcg tgagcatgat gatgcagcac cgtttgcgtc
    74281 ggcagattca tttcgcgcgc ccactggctg gagacatagc ccggatgcgc gtcatgcaca
    74341 acgtattgcg gagtgaaatc gtagatgttt tgcatcaggc gtaacgcttc gcgccactgc
    74401 atctggatgc catcgtcact taaatcgccc agatgctgac tcaacaccgc ttgttcgccg
    74461 cgcaccaggc agaaggtatt tttcagatcc gcgccgagac acagcacagg cggaacattt
    74521 ttaaagcccg gaggcaaagc cagcgcatcc ggcacatacc cccgcgaacg gcgcagcatt
    74581 tcgccgcttt cgcgcaccac cgaatcatcc atccgctgca cgatgtcgcg gttatgtatc
    74641 aagaatccgt cggcaatgcc ctgcaaatcc gccagcgcct gttcgttgct gatagccggt
    74701 ggtttaccgc tcaggttgcc ggaggtcatc accagcgggc attgcagttc ctgtaacagc
    74761 aaatgctgga gcgggttcgc aggcaacatt accccgactt cgttaaggcc aggggcgata
    74821 tcatcacaaa gctcaggtac atatttttta tccaccagca caatcggcgc ggcgggcgtg
    74881 gtaagcaact ggcgcgcagc gtctggtaaa ccgtcagcca ctggcaacat gaccgccagc
    74941 ggtttcgccg ggcgatgttt gcgcgcccga agtgtcgcca ccgcgttact gttacgtgca
    75001 tcgcaggcaa gatgaaatcc gccaatccct ttgatggcga caatgttgcc catttttaac
    75061 tgtgcgatag ctgcctgtaa tgccgcctct tgttctgcat gttcaccatg acttacccat
    75121 tcaagatggg ggccacactc cgggcaggcc accggctggg cgtggaagcg acgatcgagc
    75181 gggtcacagt actctttgtc acaagccgga cacagcggaa acgccgccat cacggtaaac
    75241 gggcggtcgt aaggcatggc gcgaataatg gtgaaacgcg ggccacagtg ggtacagttg
    75301 ataaacggat aacgataacg ccgctcgccc ggggtattca tttcggcaag gcaagcaggg
    75361 caagtcgcgg catcgggaac tatttgcgta ttcatagcgc cgcctgtgct ctggcggata
    75421 gtgaactcgg tgggcagttg tgaccagata aacggctcac gctcgacgct atcaatacgc
    75481 gccagcggcg gacaatgctg atgcaattga acaagaaagg tttccggctc ttccagcagc
    75541 cggacttcta cgccatcgcc gtcattacag acatcgccgt gaagatttaa ttgctgtgcc
    75601 agttgccaga caaacggacg aaaaccgacg ccctgcactt tgccacgaat acgcagttgg
    75661 acaccgcaag atgtgttttt tgccattgag ttattcccgc catcatgaat tgcgtaaccc
    75721 gcccagccgg acacgacagc gtcgcatccg gcagtcacag gtcggcgata ctgcccgctt
    75781 cgtattctac gaatatttcc gggaattcct ttgataccag aacagttctg taagattttt
    75841 agaacatcag cgccgtgcgg cggcgttttt ctgcgctcag ttgttcaagt ttattacgat
    75901 cgacacaaat cagcgcatgg gtcgggcaag ccgccataca cgccgggccg tcttcacgat
    75961 ggttgcacag gtcgcattta ttggcttcgg ctttgtcagc ccgtacattc agccctgcgc
    76021 cgctgttgcg aatcaccgga cgcaccacca cttccatcgc accatatggg caagccacaa
    76081 cgcaggtttt gcaaccaata caacgttcct gcatgacatg aacaaaccct ttatcacggc
    76141 tgatagcacc attcgggcag acgttagcgc acggtgcatc ttcacactga cggcagactg
    76201 tcgccgtgga aatgttcaca cctttaatga catggattcg cggtaaaaat gtttccgggg
    76261 tcagcgatgc acagtcctga ttttcctgat gagaaaccac gcacgccact tcacaggtac
    76321 ggcaaccaat acatttactc gcgtcagcaa tgatgaaacg gttcatcaaa ttctccagca
    76381 ataacagtta atgcgccgat acattcacaa atcatgccag tttttaattt actgttattt
    76441 aaggaaatta aattctgtac tacaggaaaa acgatgtcat cgacactagt gtcgatgaca
    76501 tgtgatgaca gtatttatcg tagtaaggca gagagaatcc gttttctaat gaatatttta
    76561 tcgttgccag tccacatctg ggtacttttt tccgacaagt cgttctggtg gtataaaaaa
    76621 gtaattgcca gtaacgggga ggatttaagg gaagcaaccg tgccggatac ggcgtgaaca
    76681 acgaccactt tgtcagctat ccatatgatt gtattttgag gttcatcgca gattagcgat
    76741 gaacctttat tgaataatac tatttcgact gaaataacag gtaaggatac aaaatgggtt
    76801 catggggaat ggaggctctc gaaagcgacg aagggctgga tttgattaat tgggtagagg
    76861 aacaactgca agatgattcg acctttgatg ccgagtcaat tgttcaacgc ttaagccagc
    76921 atgaagattt gttcggattt cagggagatg aagaatttct ctacgataat tacgataata
    76981 atgttatcgg tctcgttgaa cttatcattc aaaaagcagc cgggaaaaaa atcacatcga
    77041 gtaaacaaat tgatcaactc gacggttatc agctcacgtc gactttcagc aaaaaactcc
    77101 agggccgttt acaaacaatc gacgacacac atgagtggat aatgcttttc gaggggcgag
    77161 cacgcgaaaa agcaaaagca tatctgattg agcttactga taaattaaga gtagtaaaga
    77221 caacagcctg aatgacaaac aagggcgcgc aaaattaaga atctgcgccc tttcaaagcc
    77281 cgataggcgt agcgcatcag gcgatttagc gtctgccatc agtcaaagaa accattccgg
    77341 cttaacgcca aatcgggctg aaagtgcctt aatgtgggat atcgtcaggg aacgttgtcc
    77401 agataaaatc tggctgacca gggatttaga gccgatttcg ttcttcaaat ctgcataggt
    77461 cagattatgt tgatcaatca gcgtgcgaag taacgccaca ccaacaggca ttgctgcaac
    77521 ggctttgtcg aactctgcaa acttttcgtt attgttttca tattctgcaa tgcggctcgc
    77581 cagaaagtcg ataagtggat tagtatcatc ttcttcaatc aaatattcga ccagttccag
    77641 tgcttcacgg taatcatctt ctgagtcact gcctcccaga aaggggactg cattgaccag
    77701 ttctcttgtt gctttaacag cgcgtgcagc attagcagtc attctttgtt ctctctgtag
    77761 taacgtgtca gacgcccact tttctaaaat gccaggtttg ctcggcatca taaggcatgg
    77821 tcaggagagg tttcagcgcc cgcttttgcg cgtattcgct gtcactcatt ggcagatatt
    77881 cggtaaagct ggtggcctgt gcaggcagca ctaagctcaa taaaaaagcg cacatccctg
    77941 ttttgatgtt caattccctg aattccctaa tgaagaatta ttcttccacc gctaactgcg
    78001 cgaagccgcc atttccttcc cagccttcca gccgctgata caccgtttcc accgcatctt
    78061 taatcggctg agtcatcggg tagtaaaagc cgacgatatc cggctggatg ccaaggaaaa
    78121 tcacttcgcc aatatcttct ttcaactggt cgataagata gttcagcggc atgttatggg
    78181 tagtcatcat aaacatctcg gcgatgtcag ccgggtcgat gatgcggatc tcgccagggt
    78241 ttagccccat atccgtggcg tcgacaatca gcagccgtgt cgggcgcagt tcgcggatag
    78301 cgacaatgtc gttttccggt gcgctaccgc cgtcaatcac tacccagtta cctttcggcg
    78361 cggcggcgca cttttccgcc agtagcgggc ctgcgccatc atcgcccatc atgctattgc
    78421 caacacaaag taaaacgtca gtcacgcagt ctcctcacca tcaaatagat ggcgttttcc
    78481 tgatgaatat catgcagcat acttaacagc attgtactcc attccttctg ctgcgaagtt
    78541 tgcgctgccc gggctttatc gaatgcgttg gccagcatcg gcacatggtt aatgtcgatg
    78601 acgatctcac catatttcgg cacgccttcc attttacggc gggcttcgct gcccgcctcc
    78661 agagtggcaa tccatgccag atagtcatcc cacgggcagg taagtgccgc ttccaggcaa
    78721 tcgataaccc caaggtggtg accaatcgcc aggctgtaat agaccacctg ctgcgcctcg
    78781 gcgggcgtgg catcgttctc atcaataaat ttacggctca gttgactgaa caccaccttt
    78841 tcactcatcg gatacgcgcc tcttcaacaa catgattcag atggctgaca atctcgttca
    78901 gacgcggatc gttttccgct tccagccagc gtgcaacctg ttcttcgccc tgccctaact
    78961 gtgtcaggaa atcatcggca atctggcgac cgtaacgata acccgccaga cgacgcgctt
    79021 cacggtccac tttcacacgc aacggttgca ccatatcagg atgtagaatg tctgccggct
    79081 gctcatcttg ctcacccggc ccacgggcgt ggattttctg ctccagcagg ccgagcgcca
    79141 tcgcaaagcc gtacagcgtg gcggcaggcg ttggcgggca gccagggatg tagacatcta
    79201 ccggaacgat tttatccgta ccgccccaca cgcagtagag atcgtggaag atcccgccgc
    79261 tgttaccgca ggcaccgtaa gagatacaga ttttcgggtc cggcgcggac tgccacgcac
    79321 gcagcgcagg ggatcgcatt gcacgggtga ccgcgccggt aaacagtaaa atatccgcat
    79381 gacgcggtga cggaacgact ttaatgccga agcgttctgc atcgaacagc ggcgaaagcg
    79441 tggcgaaaat ttcgatttcg caaccgttac agccgccgca gtccacgcga taaacgtagg
    79501 cagaacgttt gatttttttc agtaacgacg ccttcatgct ggcgatggat tcatccaccg
    79561 tcatcgggac cggaatgccg ttggcgtcac gggggcctaa taaattgctc atcagatggc
    79621 ctctttcata tggcgagtca gttcaatacg gtcggacggc accaggcatt tctggcgctt
    79681 acattccggg caagtctcaa agctttcgcg gtggttttcc gcgcggctgt cgccgttgtg
    79741 cttaagcagc gcaatggcgt agtcgatctc tttctggacg gcgaaaggac gattgcagac
    79801 gcggcagttg cacagcgcga agcgggactg ttgcaggaag tcttctttct tccacaccgc
    79861 cagttcgtat tcttgcgaca gcttaatcgc cgccgtcggg cagacttctt cgcagcgtcc
    79921 acagaagatg cagcgtccaa gattgaactg ccacgccagc tctcctgtgg cgaggtcagt
    79981 ttcaaccgtt aaggcgtttg acgggcaggc attgacgcag gccgcacagc cgatgcactg
    80041 ctgcgggttc tgctctggct taccacggaa gtttttatca accgcaatcg gctccagcgg
    80101 ataagacgaa gtcgccgtgc cggttttgat gacttttttg ataaaggtaa acatggcgat
    80161 tccttatttc agcggcgagt ttttacgctc aatgctgtag cgctcgagtt ctttgtacgg
    80221 caccactttg ctcttcttct tacgtacatc gaccacggtc atgcggtcgg tacaggagta
    80281 gcaagggtcc aggctaccga taatcagcgg cgcatcggaa acggtattgc cacgcagcat
    80341 gtagcgcagg gtcggccagt tcgcgtaggt cgcggcacgg cagcgccagc ggtacagctt
    80401 ctggttgtcg ccggtcatgc tccagtggat atcgtcgccg cgcggcgctt cggcaaagcc
    80461 cagcgcgaaa cggtgcggaa tgtaggtaaa gccttccacc atcagcgggc cgcccggcag
    80521 gttatccaga ccgtaatcga tcatattcag cgcggtatag acttcgttga tacgcacttt
    80581 cagacgggaa ataacgtcgc agccctgctc gctgtggact tccattggca gcaggccata
    80641 accaacaaac gggtgatcgg cgcgggtatc gcgagcgtgt ccgctggcgc ggaccatcgg
    80701 gccaacgtta ctgaaatcgc gggcaatttc cgggtccaga cgaccaatgc cgacggtgcg
    80761 ctgttccatg ttcggtgtgc tcagcagcac atccaccagc tcctgcactt cacgacgcat
    80821 ctgttgcgcc agctggcggg tctgaatcat gtcgtctttc agcagatcgc gacgaatccc
    80881 gccgatcagg ttcaggccgt aggttttacg cgcaccggta aggatctctg ccattttcat
    80941 ggaggtttca cgcacgcgga agaactgcat aaagccggag tcaaagccgg taaagtgaca
    81001 ggccaggccg aggttgagca gatgcgagtg caggcgttct acctccagca gaatggcgcg
    81061 gatcatctgc gcgcgttctg gcacctgaat acccatcgcg ttttccaccg acgtggtata
    81121 ggcggtgctg tgagcaaagc cgcagatccc gcacacacgg tcagagagga aggtcacttc
    81181 gttgtaaccc atacgggttt ccgccagttt ttccatgccg cgatggacgt agaacaggcg
    81241 gtagtcggcg tcgataatgt tttcaccatc gacgaacaga cggaagtgac ccggttcgtc
    81301 agaagtgacg tgcagtggac caatcggcac gacgttgttt ttcttgtcgc ccagttcgtt
    81361 gatgaactcg taggtttcag catcggtagt cggtgccgga cgctgacgat aatccatgct
    81421 gtctttacgc agaggataaa gttcatccgg ccagtcatcc ggcagcacca gacggcgttc
    81481 atccggcaga ccaaccggaa tcaaaccgta catatcgcgc acttcacgct cgccccacac
    81541 cgccgccgga acgcgcggcg tcacggaagg atactccggt ttgttggcgt caacttcaac
    81601 gcgaaccgtt acccaacact tggtgccctt ctccatcgac agcacgtaat aaacggcgta
    81661 atgaccattc agtttgcgtt cgtcgttacc aaacagcacc gacagccagc caccctgctt
    81721 gtagtagaga aactccacca cttccggcag gtagttcacc tttacggtca cggtcagctg
    81781 atctttggtc tgccaggcgt ggtccagcac gacgccagga aatgcctcat tcagcgcggc
    81841 gagataatgt tgacctaatt tttcttcaga catgctcaaa ctctctttaa tcacgccgcc
    81901 agcaaggaga cgaacgctaa aaatgcaaag ccaaacccgg cccaggtaat gcgcggagta
    81961 atatcaagac gcagacgggc catgctgttt tcgaacagcg cgataaccag gacgccaacc
    82021 accagtttga cgatggcaat caccagcgcc agcagcagcc caccgacggt gaaggtttcc
    82081 atttgtcccc acggaataaa caccccgacg aacatctgca acaccaccag ctgtttcagg
    82141 ctgatacccc atttcatgac gccaaagccg ctgccgctat actcagagag cggaccttcc
    82201 tgcaactcct gctcggcttc cgccaggtcg aacggcagtt tgcccatttc gataaaggtg
    82261 gcgaatgcac aggcacaaag cgccagcacc agcgggatgc tctggctcag tggccagtga
    82321 taaacggtgt cggtgatgtt gctgatgttg gtggaaccgg caacctgtgc ggcgacccac
    82381 agaccaagca gcagcatcgg ttcaaccaac acgccaagca tcgcttcacg gctcgcgccg
    82441 atagcggtaa acgggctacc ggtatccaga ccagaaatgg caaagaagaa acgcgcgatg
    82501 gcgaagagat acagtaaggt gatcaaatcg cccagttgcg gcagcggaga accgacggtc
    82561 accaccggca gcgcagtggc gatagtcagc atgacgccca ccatcacata cggcgtcagg
    82621 cggaacaccc agccggaggc atccgggcca acgctctggc ggcccagcag tttgataatg
    82681 tcgcgatact cctgcaacac acccggccca cgacggttat gcagacgggc gcgtgctacg
    82741 cgggtaatac cggagagcag cggcgcaacg gcaaatagca ccagcgcctg aattaacgga
    82801 tataaaacac tcattctcag gctcctcgtg aaacaataat caccaccagc accgccagtt
    82861 caaccagcgc catccggcgg aacagcaacg cactcccctc gcactgccag cccggcacca
    82921 gagacaccgg attcagccat ttgcgtagtt tcagcaccgg cgcaaacgcc tgtttcaccg
    82981 gcatggcaaa accgtgagcg gtaatcacca ttgatttttc atgatcgtag ccgcacaccc
    83041 aggccgcgcc gcgggaacgc gacggcaaac gatcgccttt gcaaatcgcc ataatgatga
    83101 atggcagcag cgggcaggca atcaacaaca acgtgatcat tggttgagaa acggtggtgt
    83161 tagcaggctc cagcggcaga ggtacagcag cagagagcat cggcagtagc cacggcgcag
    83221 caacaccgcc aattacgcag caaatcgcca gtgccactac gcttacgctc atcaggagcg
    83281 gcgaacaggt ggcgttttcg gcttctttgg tacgcggcgc gccgaggaaa gtaacgccat
    83341 aaactttcgc catacacatc accgccagcg caccggtaat tgccagcccc acggcgagca
    83401 gcggcccgag aagacgggca acaaacgcgc cactattgct cagtttgaag aaggattgat
    83461 agataaccca ttccccggca aaaccgttca gcggcggcag cgcagccatt gccatcagcc
    83521 cgactaacat ggcgatggag ataaccggca ttttcttgcc aataccaccg agtttttcga
    83581 tatcgcgatg accggtacgg aaccagacgc tccccgcacc aaggaacagt acgctcttga
    83641 acaggctatg gttaagcaga tggtacagac caccaaccag accaagggca atcagcgccg
    83701 gttgttcgag cgcgataccc gttacgccag cgcccagccc cagcaggatg atgccgatat
    83761 tttccagggt gtggtaagcc agcagacgtt ggatattatg ttccatcaac gcatacagac
    83821 cgccgacgaa tgcggtgatc atgccgagta ccagcagtgc gatcccccac cacagcggtg
    83881 cattaccgcc cagtagtgac agagttaaaa tgcccagcag gccaattttc atgactaccg
    83941 tggaaaacag cgcggcagct ggcgcagagg cgttggcatg tgcctgtggc acccagccgt
    84001 gcagcggaat aatcccggcc agcaggccaa agccaatcac accgagcagc cagatatcgg
    84061 aaccgagcgg cagctgttgc atacgcatat ccagcaggcg cagatccagc gtgccgtaac
    84121 gctgccacag cagccagcag gcaatcgcca gcagcagagt gccaagacgc cccagcgcaa
    84181 accacagttt gccctctttg ctgttgctgg tgaggaacac cgcacacagg gccatgattt
    84241 cggccattac cacgaacatg ccgaggttgc tggcgatgac ggcacagacg gcggcagcca
    84301 tcaacatatt gatctgcaag ccgttgcact tcacctgcgc gtggcgatgc cagtcaatgt
    84361 tgtagaggct gacaaacaga ccgcacagac cgagcgtaat cagccaaatc gcgttaagcg
    84421 gagagatttg cacatcgtag cttaccaacg acagcgcacc gctcacgcca accgcgccag
    84481 tcagcacagt gaagcccgcg gctgccgtat acaggctacc caccgcgccg ccaattccgg
    84541 ctatccagcc acttagcgct ttttgaaaag aaaagagaaa tgccagaaca gcggcggcga
    84601 caaaccacgc cacgccgcta ttgatcaggg aaattgcgct catttagcct ctccactttg
    84661 agcctgctga aacaaggtga gatcgccaaa gtccgtgtta aaagtcagct cacgcttacg
    84721 tttgctgacg cgggcgatat cggtgttatc caccagatgc agggctttag tcgggcacat
    84781 ccgcacgcag gccggacctt gttcatcaaa gctacaaagg tcacatttga cggcgatcgc
    84841 gcgaatacct ggcacccagt caagcaatgt gctgacacgc gccggagcag gcggtgccgg
    84901 tggcgctttc ggggtattgg tgtttgccgg aatatccagc ggacggctgc cggaaaattc
    84961 aattgcgcca aacgggcagg cgatgccaca cagtttgcag cttacgcaca agctttcatt
    85021 cagctgtacg gcaccatcaa cacgagtgat ggcgttaacc gggcagaccg ttgcgcaggg
    85081 tgcatcttca cagtggtgac agagctgcgg cgcagattct ttttcattga gcatcactcg
    85141 caggcgcggc attgattgca ggccgtgctg gcgatgcgtc tctgaacagg cagcctcaca
    85201 agtgtggcag ccgatacaga gcgtggagtc agcaattaca aaacgattca ccaggcattc
    85261 ctcaggtgat tgtcattttt gacgaaaaca tgccgatgaa atgtcatttt cgacactcat
    85321 cgacacgccc atccccaaac aggcgtaacg cctgcaaaac gggcaaagcc tcagctcatg
    85381 ctaccgggct ttgtcccttt accagttggc ttaaattcac cggcacattg ttttcaatgg
    85441 cggtatataa gctgtcgtaa acgccagcga ttttttcgag atagtgttcc agaacttgtt
    85501 cgcgatcgcg gatgttgacc ttgccatcaa tcatgccgtc aatgctcaac tgcgcctgcg
    85561 caatccgctg tttgtcttcg ccatcttttg tttcgacgta atactcgatg gtgtggctgt
    85621 taaagccatc cgccagggtg acgtaaatgc gaaaatgttc aaaaaggacg aaacagagtt
    85681 ctttgtccgg cgcgcagctc atggcgtgat gcaggcgcgc tttcgataac gtgatcccct
    85741 gaaccagcga attgcagtag atgtgccact ggtcctgtag gcgacgatgc cgctgtgcga
    85801 tgtaatcggc tttctcgctt atttcccaaa tagtcattgt caggttaccc gtttaacaga
    85861 gatgccagct ttaagcattt tctgtgccaa cttttaattc attgttatta aagcgatttc
    85921 taagctaaag atgaatttcg tcgccgtgtc gacgtgtcat ttcgacatca tcgacattat
    85981 tcaccgcagg gataatcaac actggcacaa ttattgcttg tagctggcaa tagttaatgg
    86041 gaggcgatat gcacgaaata accctctgcc aacgggcact ggaattgatc gaacagcagg
    86101 ccgcaaaaca cggcgcaaaa cgcgtaactg gggtctggct caaaattggc gcattttctt
    86161 gtgtcgaaac cagctctctt gccttttgtt ttgatctggt ttgccgcggc agcgtggcgg
    86221 aaggttgtaa actgcacctc gaagaacaag aggccgaatg ctggtgtgaa acatgccaac
    86281 agtatgtgac gctactgacc cagcgcgtcc gccgctgtcc acagtgtcat ggtgacatgc
    86341 tacagattgt ggcagacgac ggtttacaga ttcggcggat agaaatagac caggagtgag
    86401 cgatgtgtac aacatgcggt tgcggtgaag gcaacctcta tatcgagggt gatgaacata
    86461 accctcattc cgcgtttcgt agcgcgccat ttgccccggc ggcacgcccg aagatgaaaa
    86521 tcaccggcat taaagcgcct gaatttaccc ccagccagac tgaagaaggc gatctgcatt
    86581 acggtcatgg cgaagcgggc actcacgcgc cgggcatgag ccagcgtcgg atgctggaag
    86641 tcgaaattga cgtgctggac aaaaataacc gtctggctga acgcaaccgc gcgcgctttg
    86701 ctgcccgcaa gcaactggtg ctcaacctgg tttccagccc tggttccggt aaaaccaccc
    86761 tgctgacgga aactttaatg cgcctgaaag acagcgttcc gtgcgcggtt attgaaggtg
    86821 accagcaaac cgtgaacgat gccgcacgca ttcgcgctac cggcacccca gcgattcagg
    86881 tgaacaccgg taaaggctgc catcttgacg cacagatgat tgccgacgcc gcgccgcgcc
    86941 tgccactgga cgataacggt attctgttta tcgaaaacgt cggtaacctc gtttgcccgg
    87001 ccagcttcga tctcggtgaa aaacacaaag tggcggtgct ttccgttacc gaaggtgaag
    87061 acaaaccgct gaaatatccg cacatgtttg ccgccgcctc gctgatgctg ctcaacaaag
    87121 ttgacttgct gccgtatctc aactttgacg ttgagaagtg catcgcctgc gcccgtgaag
    87181 tcaatccaga aattgaaatc atccttattt ccgccaccag cggcgaaggg atggaccagt
    87241 ggctgaactg gctggagaca cagcgatgtg cataggcgtt cccggccaga tccgcaccat
    87301 tgacggcaac caggcgaaag tcgacgtctg cggcattcaa cgcgatgtcg atttaacgtt
    87361 agtcggcagc tgcgatgaaa acggtcagcc acgcgtgggc cagtgggtac tggttcacgt
    87421 tggctttgcc atgagcgtaa ttaatgaagc cgaagcacgc gacactctcg acgccttaca
    87481 aaacatgttt gacgttgagc cagatgtcgg cgcgctgttg tatggcgagg aaaaataatg
    87541 cgttttgttg atgaatatcg cgcgccggaa caggtaatgc agttaattga gcatctgcgc
    87601 gaacgtgctt cacatctctc ttacaccgcc gaacgccctc tgcggattat ggaagtgtgt
    87661 ggcggtcata cccacgccat ttttaaattc ggcctcgacc agttgctacc ggaaaacgtt
    87721 gagtttatcc acggtccggg ttgcccggtg tgcgtactgc caatgggtag aatcgacacc
    87781 tgcgtggaga ttgccagcca tccggaagtc atcttctgta cctttggcga tgccatgcgc
    87841 gtaccaggga aacaggggtc gctgttgcag gcaaaagcac gcggtgccga tgtgcgcatc
    87901 gtttactcgc caatggatgc gttgaaactg gcgcaggaga atccaacccg taaagtggta
    87961 ttcttcggct taggttttga aaccaccatg ccgaccaccg ccatcactct gcaacaggcg
    88021 aaagcccgcg atgtgcagaa tttttacttc ttctgccagc acattacgct tatcccgaca
    88081 ctgcgcagtt tgctggaaca gccagataac ggtatcgacg cgttcctcgc gccgggccac
    88141 gtcagtatgg ttatcggcac tgatgcctat aattttatcg ccagcgattt tcatcgtccg
    88201 ctagtggtcg ctggtttcga accccttgat ctacttcaag gcgtggtgat gctggtggag
    88261 cagaaaatag cggcccacag caaggtagag aatcagtatc gtcgggtggt accggatgcc
    88321 ggtaacctgc tggcgcaaca ggccattgct gatgtgttct gtgtcaacgg cgacagtgaa
    88381 tggcgcggct taggcgtgat tgaatcttct ggcgtgcacc tgacgccgga ttatcaacga
    88441 ttcgatgccg aagcacattt ccgcccggca ccgcagcagg tctgcgatga cccgcgtgcg
    88501 cgttgtggcg aagtcttgac gggcaaatgt aagccgcatc aatgcccgct gtttggtaac
    88561 acctgtaatc ctcaaaccgc gtttggtgcg ctgatggttt cctccgaagg agcgtgcgcc
    88621 gcgtggtatc agtatcgtca gcaggagagt gaagcgtgaa taatatccaa ctcgcccacg
    88681 gcagcggcgg ccaggcgatg cagcaattaa tcaacagcct gtttatggaa gcctttgcca
    88741 acccgtggct ggcagagcag gaagatcagg cccgtcttga tttggcacag ctggtagcgg
    88801 aaggcgaccg tctggcgttc tccaccgaca gttacgtcat tgacccgctg ttctttcctg
    88861 gcggtaatat cggcaagctg gcgatttgcg gcaccgccaa tgacgttgcg gtcagtggcg
    88921 caattccgcg ctatctctcc tgtggcttta tcctcgaaga aggattgccg atggagacac
    88981 tgaaagccgt agtgaccagc atggcagaaa ccgcccgtgc ggcaggcatt gccatcgtta
    89041 ctggcgacac caaagtggta cagcgcggcg cggcagataa actgtttatc aacaccgctg
    89101 gcatgggcgc aattccggcg aatattcact ggggcgcaca gacgctaacc gcaggcgatg
    89161 tattgctggt tagcggtaca ctcggcgacc atggggcgac tatccttaac ctgcgtgagc
    89221 aactagggct ggatggagaa ctggtcagcg actgcgcggt gctggcgccg cttattcaga
    89281 cgctgcgtga cattcccggc gtgaaagcgc tgcgtgatgc cacccgtggt ggtgtaaacg
    89341 cggtggttca tgagttcgcg gcagcctgcg gttgtggtat tgaactttca gaagcggcac
    89401 tgccggttaa acctgctgtg cgcggcgttt gcgaactgct gggactggac gcccttaact
    89461 ttgccaacga aggcaaactg gtgatcgccg ttgaacgcaa cgcagcagag caagtgctgg
    89521 cggcgttaca ttcccatcca ttgggaaaag atgcggcgct gattggcgaa gtagtagaac
    89581 gtaaaggtgt tcgtcttgcc ggtctgtatg gcgtgaaacg aaccctcgat ctaccgcacg
    89641 ccgaaccgct tccgcgtata tgctaataaa attctaaatc tcctatagtt agtcaatgac
    89701 cttttgcacc gctttgcggt gctttcctgg aagaacaaaa tgtcatatac accgatgagt
    89761 gatctcggac agcaagggtt gttcgacatc actcggacac tattgcagca gcccgatctg
    89821 gcctcgctgt gtgaggctct ttcgcaactg gtaaagcgtt ctgcgctcgc cgacaacgcg
    89881 gcgattgtgt tgtggcaagc gcagactcaa cgtgcgtctt attacgcatc gcgtgaaaaa
    89941 gacaccccca ttaaatatga agacgaaact gttctggcac acggtccggt acgcagcatt
    90001 ttgtcgcgcc ctgatacgct gcattgcagt tacgaagaat tttgtgaaac ctggccgcag
    90061 ctggccacag gtgggctata ccccaaattt ggtcactatt gcctgatgcc actggcggcg
    90121 gaagggcata tttttggtgg ctgtgaattt attcgttatg acgatcgccc ctggagcgaa
    90181 aaagagttca atcgtctgca aacatttacg cagatcgttt ctgtcgtcac cgaacaaatc
    90241 cagagccgcg tcgttaacaa tgtcgactat gagttgttat gccgggaacg cgataacttc
    90301 cgcatcctgg tcgccatcac taacgcggtg ctttcccgcc tggatatgga cgaactggtc
    90361 agcgaagtcg ccaaagaaat ccactactac ttcgacattg acgatatcag catcgtctta
    90421 cgcagccacc gtaagaacaa actcaacatc tactccactc actatcttga taaacagcat
    90481 cccgctcacg aacagagcga agtcgatgaa gccggaaccc tcaccgaacg cgtcttcaaa
    90541 agtaaagaga tgctgttgat taatctccac gagcgggacg atttagcccc ctatgaacgc
    90601 atgttgttca acacctgggg caatcagatt caaaccttgt gcctgttacc gctgatgtct
    90661 ggcgacacca tgctgggcgt actgaaactg gcgcaatgcg aagagaaagt ctttaccact
    90721 accaatctga atttactgcg ccagattgcc gaacgtgtgg caatcgctgt cgataacgcc
    90781 ctcgcctatc aggaaattca tcgtctgaaa gaacggctgg ttgatgaaaa cctcgccctg
    90841 accgagcagc tcaacaatgt tgatagtgaa tttggcgaga ttattggccg cagcgaagcc
    90901 atgtacagcg tacttaaaca agttgaaatg gtggcgcaaa gtgacagtac cgttctgatc
    90961 ctcggtgaaa ctggtacagg taaagagctg attgcccgcg cgatccataa tctcagtggg
    91021 cgtaataatc gccgcatggt caaaatgaac tgcgcggcga tgcctgccgg attgctggaa
    91081 agcgatctat ttggtcatga gcgcggggct tttaccggtg ccagcgctca gcgcattggt
    91141 cgttttgaac tggcggataa aagctcacta ttcctcgatg aagtgggcga tatgccgctg
    91201 gagttacagc cgaagttgct gcgtgtatta caggaacagg agtttgaacg tctcggcagc
    91261 aacaaaatca ttcagacgga cgtacgttta attgccgcga ctaaccgcga tctgaaaaaa
    91321 atggtcgccg accgagagtt ccgtagcgat ctctattacc gcctgaacgt attcccgatc
    91381 cacctgccgc cactacgcga gcgtccggaa gatattccgc tgctggcgaa agcctttacc
    91441 ttcaaaattg cccgtcgtct ggggcgcaat atcgacagca ttcctgccga gacgctgcgc
    91501 atcctgagca acatggaatg gccgggcaac gtgcgtgagc tggaaaacgt catcgagcgc
    91561 gcggtattgc taacacgcgg caacgtgctg cagctgtcat tgccagatat tgctttacca
    91621 gaacctgaaa cgccgcctgc cgcaacggtt gtcgcccagg agggcgaaga tgaatatcag
    91681 ttgattgttc gcgtgctgaa agaaacaaac ggcgtggttg ccgggcctaa aggcgctgcg
    91741 caacgtctgg ggctgaaacg cacgactctg ctgtcacgaa tgaagcgact gggaattgat
    91801 aaatcggcat tgatttaaca gatgtggtta tactcgatca acattcaatg aaaggaggca
    91861 gtatggcagt ttcagcaaga aatcaattaa ccggaacagt tagcgcagta gcaatgggcg
    91921 cggtgaatga cgaagtagaa ctgacgctgg caggtggtgc aaagctggtg gcaattgtga
    91981 ctcacagcag ccagcaagcg ctgggtctgg cgaaagggaa agaagcgatt gccctgatta
    92041 aagccccgtg ggtaacgctg gcaacggaag actgtggact gaaattctct gctcgcaacc
    92101 agtttgctgg cagcgtgtcg acaatcaccg aaggcgcagt gaacgccact gtccatatca
    92161 aaacggatgc gggttttgaa attgtggcag tggtaacaaa tgaaagtcag gatgaaatga
    92221 aactcaccac tggctcgcgc gttattgcat tgatcaaagc atcagccatc ctgattgcca
    92281 ccaaagcgta agcgccgtat ttgccggaga gtatggctct ccggcagatt tatttctttg
    92341 gacgatattt ttctggcaac tccggcaccg gacgcttgtc atcgatgaga tgacgcacgg
    92401 ttaagatcgg atgacgccac agcattctcg gcccggccca acgcataatc tgtttcatct
    92461 cttcacgctt tgcaggctgg taacagtgca ccggacactg cttacaggct ggtttctctt
    92521 cgccgaacac acatttatcc agccgctttt gcgcgtaagc aaacaacgcc tcgtaatgct
    92581 ccggctctgc tgacgcctgc gggcatttcg cttgataaag atcgatcatt tttttaatcg
    92641 tcagtttttc acgagagata cgcttgccgg acatgctgcc tccatactct taaggtgcat
    92701 ttatattaca acttaatttt aaaggggact atggctctga aggaggaggt ttcttcaacc
    92761 gacgaatttg gcgatcttgt ttcatcgtca tcacgcaaaa gctgcaaagc agcatttttc
    92821 gcggaaccga catcaagaac tcacctttcg cgtcttcccc tgaaatgatt aactccggta
    92881 tcatgtgcgc cttatgtgat tacaacgaaa ataaaaacca tcacactaca tttaacatca
    92941 gggagccgga cttaacccca tgagtacaat agaaaatttc gacgcccata cgcccatgat
    93001 gcagcagtat ctcaagctga aagcccagca tcccgagatc ctgctgtttt accggatggg
    93061 cgacttttat gaactgtttt atgacgacgc aaaacgggcg tcgcaactgc tggatatttc
    93121 actgaccaaa cgcggtgctt cagcgggaga gccaatcccg atggcgggga ttccctacca
    93181 tgcggtggaa aactacctcg ccaaactggt gaatcagggc gaatccgtcg ctatttgtga
    93241 acagattggc gatccggcga ccagcaaagg gccggtcgag cgcaaagttg tccgtatcgt
    93301 tacgccgggc accatcagcg atgaagcgct gttgcaggaa cgtcaggaca acctgctggc
    93361 ggctatctgg caggacagta aaggtttcgg ctacgcaacg ctggatatca gttccggtcg
    93421 ttttcgcctg agcgaaccgg cggaccgcga aacgatggcg gcagaactgc aacgtacgaa
    93481 tccagcggaa ttactgtatg cagaagattt cgccgagatg tcgctgattg aaggtcgccg
    93541 cggcctgcgt cgtcgcccgc tgtgggagtt tgaaatcgac accgctcgcc agcaattgaa
    93601 cctgcaattt ggcacccgag atctggtcgg ttttggtgtg gagaacgcac cacgcggact
    93661 ttgtgctgcc ggttgtctgt tgcagtatgc gaaagatacc caacgcacga ccctgccgca
    93721 tatccgttct atcactatgg aacgtcagca ggacagcatc attatggatg ccgcgacgcg
    93781 tcgtaacctg gaaattactc agaacctggc cggcggtgcg gaaaatacgc tggcttcagt
    93841 gctcgactgc actgtaacgc cgatgggtag tcgtatgttg aaacgctggc tgcatatgcc
    93901 agtgcgcgat acccgcgtgt tgcttgagcg tcagcaaact attggcgcat tgcaggattt
    93961 caccgccgag ctgcagccgg tactgcgtca ggtgggcgac ctggaacgta ttctggcgcg
    94021 tctggcgttg cgtaccgctc gcccacgcga tctggcccgt atgcgtcacg ctttccagca
    94081 actgccggag ttgcgtgcgc agttagaaaa tgtcgatagt gcaccggtac aagcgctgcg
    94141 tgagaagatg ggcgagtttg ccgagctgcg cgatctgctg gagcgagcaa tcatcgacac
    94201 accaccggtg ctggtacgcg acggtggtgt tatcgcatcg ggctataacg aagagctgga
    94261 tgagtggcgc gcgctggctg acggcgcgac cgattatctg gagcgtctgg aagtccgcga
    94321 gcgtgaacgt accggcctgg acacgctgaa agttggcttt aatgcggtgc acggctacta
    94381 cattcaaatc agccgtgggc aaagccattt ggcaccaatc aactacatgc gtcgccagac
    94441 gctgaaaaac gccgagcgct acatcattcc agagctaaaa gagtacgaag ataaagttct
    94501 cacctcaaaa ggcaaagcac tggctctgga aaaacaactt tatgaagagc tgttcgacct
    94561 gctgttgccg catctggaag cgttgcaaca gagcgcgagc gcgctggcgg aactcgacgt
    94621 gctggtgaac ctggcggaac gggcctatac cctgaactat acctgcccga ccttcattga
    94681 taaacctggc attcgtatta ccgaaggtcg ccatccggta gttgaacaag tactgaatga
    94741 gccgtttatc gctaacccgc tgaacctgtc gccgcagcgt cgcatgttga tcattaccgg
    94801 tccgaacatg ggcggtaaaa gtacctatat gcgccagacc gcgttgattg cgctgatggc
    94861 gtatatcggc agctacgtac cggcgcaaaa agtcgagatt ggcccgattg accgtatctt
    94921 tacccgcgta ggtgctgcgg atgatctggc ttccgggcgt tcaaccttta tggtggagat
    94981 gaccgaaacc gccaatattt tacataacgc caccgaatat agtctggtgt tgatggatga
    95041 gatcgggcgt ggaacgtcca cttacgatgg tctgtcgctg gcgtgggcgt gtgcggaaaa
    95101 tctggcaaat aagatcaaag cgttgacgct gtttgctacc cactatttcg agctgaccca
    95161 gttaccggag aaaatggaag gcgtcgccaa cgtgcatctc gatgcactgg agcacggcga
    95221 caccattgcc tttatgcata gcgtgcagga tggcgcggcg agcaaaagct acggcctggc
    95281 ggttgcagct ctggcgggtg tgccaaaaga ggttattaag cgcgcacggc aaaaactgcg
    95341 tgagttggaa agcatttcgc cgaacgccgc tgctacgcaa gtggatggta cacaaatgtc
    95401 tttgctgtcc gtaccggaag aaacttcgcc tgcggtcgag gcactggaaa acctcgaccc
    95461 ggattcactg actccgcgtc aggcgctgga atggatttat cgcttgaaga gtctggtgta
    95521 ataataattc ccgatagcct tttgctatcg ggaatattaa cgacaactga cgaatcaaat
    95581 aaaaataccc tgtataatag gaaaacttat tttacagggt aaaaccatgc catctacacg
    95641 ctatcaaaaa atcaatgccc atcactatcg ccatatatgg gccgttggtg atattcatgg
    95701 tgactatcaa ttattacaat cccgcttaca tcaactctct ttttgtcctg aaaccgactt
    95761 acttatttcg gtaggcgata acatcgatcg tgggccggag agtcttaacg tgctgcgcct
    95821 gttaaaccag ccctggttta tctccgtcaa aggcaaccac gaagcgatgg cgcttgaggc
    95881 attcgaaact ggcgatggaa atatgtggct tgccagcggt ggtgactggt ttttcgattt
    95941 aaatgattca gagcaacaag aggcaataga tctgttgctg aaattccatc tccttccaca
    96001 tattattgaa atcactaacg acaacataaa atatgtcatc gcacatgcag attatccggg
    96061 gaaggagtat cagtttggca aagaaatagc ggagagcgaa ttactctggc ctgttgatcg
    96121 tgtgcagaaa tcacttaata gcgaattaca aaaaataaac ggcgccgact tctttatatt
    96181 tggtcatatg atgtttgata acattcagac gttcgctaac cagatttata tagataccgg
    96241 atcgccgaaa agcgggcggc tgtcatttta taaaataaag tagtctcatg cttcttctgt
    96301 gaagcatgag taacccggcg ttattgcagg tcattattca tttttcgcta ccagcaaaga
    96361 gagatccagc ttcgccagcg cgcggctggc actctccggc agaccgtcgt cagtaatgat
    96421 ctgatcaaac tcgcttaatg gtaacgccag ccatgtcgcc acctgtccat atttcgtcgc
    96481 atcacagacc aaaactcgct ggcggctggc actggcaatc gcccgtttca ccgtgacttt
    96541 atcttctgct ggcgtagaga tcccccgcac actccatgac gatgcagaaa taaaagcctg
    96601 atcaatcatc aggctacgca gcatggtcgc agcggcttcc ccaacacagg aacggttttc
    96661 ccgacacact gcgccgccag tgtgaataat tgtgcaatta ctgttgtcga gcaagtagtc
    96721 cgcaataacg aagtcgttag taaccactgt gagtggctcc atgtgaatca gatgctgtgc
    96781 aatcgctaac gtggtcgttc ccgcatccag atagatacaa cgtcccggct gaacaagact
    96841 tgccgccagc ttgccaatag ccgctttttg cgtcattgcc agcgcagttt ttacctgatg
    96901 agaaggttca tgcgccacgc gtcccggaga ctggacgccc ccggacacca gcacaacggc
    96961 tccctgctgc tccagttttt gtaaatcccg acgaatggtc atatgtgaca cattcattct
    97021 gtccgttagt tcagcaatac taacaatgcc tttttcagct accatctcaa ggatgatttg
    97081 gcgacgctct acgggtatca acttttgctc cttcctttgt cctgctgaca ttctacgcta
    97141 tttgcctgcg aaacgtgcgc ggcgcaacta acgcttagtt cacataaaat aacacacaat
    97201 gttaattttt gtgaatcagc tcaccatatc gttatctttc cgcgcttata ttcacaatat
    97261 caaacaaaat atcacttaaa ttaacaagga gagcagatga aaacgggatc ggagtttcat
    97321 gtcggtatcg ttggcttagg gtcaatggga atgggagcag cactgtcatg tgtccgcgca
    97381 ggtctttcta cctggggcgc agacctgaac agcaatgcct gcgctacgtt gaaagaggct
    97441 ggtgcttgcg gggtttctga taacgccgcg acgtttgccg aaaaactgga cgctctgctg
    97501 gtgctggtgg tcaatgcgac ccaggttaaa caggtgctgt ttggtgaaaa aggcgttgca
    97561 caacatctga aacccggtac ggcagtaatg gtttcttcca ctatcgccaa tgctgatgcg
    97621 caagaaattg ctaccgctct ggctggattc ggtctggaaa tgctggatgc gccggtttct
    97681 ggtggtgcgg taaaagccgc taacggtgaa atgactgtca tggcctccgg tagcgatatt
    97741 gcctttgaac gactggcacc cgtgctggaa gccgttgccg gaaaagttta tcgcatcgga
    97801 gcagaaccgg gactgggttc gaccgtaaaa attatccacc agttgttggc gggcgtacat
    97861 attgctgccg gagccgaagc gatggcgctt gcagcccgtg cggggatccc gctggatgtg
    97921 atgtatgacg tcgtgaccaa tgccgccgga aattcatgga tgttcgaaaa ccggatgcgt
    97981 catgtggtgg atggcgatta caccccgcat tcagccgtcg atatttttgt taaggatctt
    98041 ggtctggttg ccgataccgc caaagccctg cacttcccgc tgccattggc ctcaacagca
    98101 ttgaatatgt tcaccagcgc cagtaacgcg ggttacggga aagaagacga tagcgcagtt
    98161 atcaagattt tctctggcat caccctaccg ggagcgaaat catgatcaag attggcgtta
    98221 tcgctgatga ttttaccggc gcgacggata tcgccagttt tctggtggaa aacggtctac
    98281 caacggtaca aattaacggt gttccaacag gtaaaatgcc ggaagcaatc gacgcactgg
    98341 tgatcagcct gaaaacgcgc tcctgtccgg tggttgaagc cacacagcaa tcgctggcgg
    98401 ctctgagctg gttgcaacag caaggttgca aacagatcta tttcaaatac tgctctactt
    98461 tcgacagtac ggcgaaaggg aatatcggcc cagttaccga tgcattaatg gatgctctcg
    98521 acacaccgtt tacggtcttc tctccggccc tgccagtcaa cggacgtacg gtttatcagg
    98581 ggtatttgtt cgtaatgaat caactgctgg ccgaatccgg aatgcgccat cacccggtaa
    98641 atcccatgac cgacagctat cttccccgtc tggttgaagc gcaatccaca gggcgctgcg
    98701 gcgtcgtttc agcacatgtt ttcgaacaag gtgtgaaagc cgttcgtcag gagctggctc
    98761 gcttacagca agagggctat cgctacgcgg tgcttgatgc gctgaccgaa caccatctgg
    98821 aaattcaggg ggaagccttg cgcgatgccc cactggtaac gggcggttct ggtctggcga
    98881 ttggcctggc ccggcagtgg gcgcaagaaa acggtaacca ggctcgcgaa gcagggcgtc
    98941 cgctcgctgg gcgcggcgta gtgctctccg gttcatgctc tcaaatgacc aaccgccagg
    99001 tggcacatta ccgtcaaatt gcaccagccc gtgaggttga tgtggcacgc tgcctctcaa
    99061 ccgaaactct ggccgcttat gcacacgagc tggcagagtg ggttctgggc caggaaagtg
    99121 tacttgctcc actggttttt gccaccgcca gcactgacgc attggcagca attcaacagc
    99181 aatacggtgc acaaaaagcc agtcaggcag tagaaactct gttttctcaa ctagcggcgc
    99241 ggttagcagc ggaaggcgtg acacgcttta ttgtcgcagg cggtgagacc tccggcgtag
    99301 tcacacagag cctgggcata aaagggtttc atattggccc aaccatttcc cccggcgtgc
    99361 cgtgggtaaa cgcactggat aagcctgtct cactcgccct taaatctggc aacttcggtg
    99421 atgaagcctt tttttcacga gcccaaagag agtttttatc atgagcgatt tcgcaaaagt
    99481 agagcagtct ttgcgagagg agatgacgcg gattgccagt tcattctttc agcgcggata
    99541 tgcaaccggt tcggctggca atctgtcgct gcttttacct gacgggaatt tactggcgac
    99601 accgacaggt tcatgcctgg gcaatctcga tccgcagcgg ctttccaaag tcaccgcgga
    99661 tggcgaatgg ttaagtggtg acaacccctc gaaagaggtg ctctttcatc tggcgctgta
    99721 tcgcaacaat ccgctctgta aagcggtggt gcatttgcac agtacgtggt cgacggcgct
    99781 ttcctgcctg gaagggctgg acagcaataa cgttattcgt ccgttcacac catacgtggt
    99841 gatgcggatg ggaaacgtcc cgctggtgcc ctattaccga ccgggcgata aacgcatcgc
    99901 acaggatctg gcggaactgg cagcagacaa tcaggctttt ttactggcaa atcatggccc
    99961 agtggtttgc ggtgaaagcc tgcaagaagc cgccaacaat atggaagagc tggaggaaac
   100021 ggcaaagctg atttttattc tcggtgaccg cccgatccgt tatctgaccg caggtgaaat
   100081 tgcggaatta aggagttaat gcaatgcctc gttttgcagc taatttatcc atgatgttca
   100141 ccgaagtgcc ttttattgaa cgcttcgccg cagcgcgaaa agccgggttc gatgctgtgg
   100201 agtttctgtt tccctatgac tactcccccc agcaaatcca gcagcaactg gtgcaaaacc
   100261 atctgacact ggcgctgttc aataccgctc ccggagatat taatgcggga gaatggggat
   100321 tatccgccct tcccggacgt gagcacgaag cacgcgcaga catcgacctg gcactggaat
   100381 atgcattggc gctcaattgt gaacaagtcc atgtgatggc aggcgtcgtg cccgctggcg
   100441 aagatgctga acggtaccgg gcagtattta ttgataatct ccgctacgct gccgaccgct
   100501 ttgcgccaca cggcaagcga atattggttg aagcactcag ccccggcgtt aagcctcatt
   100561 atctcttctc cagccagtat caggcactgg ctattgttga agaggttgcg cgagataacg
   100621 tgtttattca actagatact ttccatgcgc aaaaagtaga tggcaacctg acacatttaa
   100681 tccgcaacta cgccgggaaa tatgcgcacg tacaaattgc cggactacct gatcgacatg
   100741 aaccggacga tggagaaatc aactatccgt ggctgttccg cctgttcgat gaagtgggat
   100801 atcagggctg gatcggttgt gaatacaaac ctcgtggcct caccaaagaa gggcttggct
   100861 ggtttgacgc ctggcgctaa ttcgctcaat ccctaattac aacgtaccca tacatccccc
   100921 catctacgga tggggtaggt taactataac tttcagacag ggtttcccat gtccacaatt
   100981 acattgttat gcattgcgtt agctggcgta atcatgctgt tgctactggt catcaaggca
   101041 aaggtacaac cattcgttgc tctgctcctc gtcagcctgt tagtcgcact tgcggcgggt
   101101 ataccggcgg gcgaagtggg taaagtgatg atcgccggga tgggcggtgt gcttggttcc
   101161 gtcactatta ttattggtct tggcgctatg ctggggcgta tgatcgaaca ctctggtggt
   101221 gcagagtcac tggctaatta tttcagtcgc aagttaggtg acaaacgaac tatcgctgcg
   101281 ctgactctgg cagcgttctt cctcggcatt cccgtcttct ttgatgtcgg ctttattatt
   101341 cttgcgccaa tcatttacgg ttttgccaag gttgccaaaa tatcaccact caaatttggc
   101401 ctgcctgtcg ctgggatcat gctcactgtt cacgtggcgg taccgccgca tccaggccct
   101461 gtcgccgcag cgggattact ccacgcagac atcggctggc taaccatcat cggtattgcg
   101521 atttctattc ccgtagggat tgttggctac tttgcagcga aaataatcaa taagcgccaa
   101581 tatgcgatgt cggtcgaggt actggaacag atgcaactgg ctccggccag tgaggaaggc
   101641 gcgacaaaat taagcgataa aataaatcca ccgggcgtcg cgttagtcac ctcgctaatt
   101701 gttattccta tcgcgattat catggcggga acggtttctg caacactgat gccgccttcg
   101761 catcccctgc ttggtacgct acagttgatc ggctcaccaa tggtagctct aatgattgcg
   101821 ctggtgctgg cattctggtt attggcttta cgtcgcggct ggagcttaca acacaccagc
   101881 gacattatgg gctctgccct tcccactgcg gcggtagtga ttttggttac tggtgctgga
   101941 ggggtatttg gcaaagtgct ggtggaatcg ggcgtcggta aagcccttgc caacatgtta
   102001 caaatgattg acctgcctct gttaccagcc gcatttatta tttcactggc gctgcgtgca
   102061 tcgcaggggt cagcaaccgt agcaatcctg acaaccggcg ggttactctc agaagcggtg
   102121 atgggattga atccaattca gtgcgtattg gtgacgctgg cagcctgctt tggtgggctt
   102181 ggcgcgtcac atattaatga ctcagggttc tggattgtga ccaaatatct ggggttgtcg
   102241 gtagcagacg gtctgaaaac ctggacagtg ttaacgacca ttctcggttt taccggattc
   102301 ttaattacct ggtgcgtatg gctcgtcatc taataatcca gataagatat gatgtatcgt
   102361 ttaagtgcct gataagggtg taatgtatgc caatattaac ctcggtaata tctcgctacc
   102421 gaggttaatt ttcactttgc aatataatta cagtctcttg caagttgatt ttatcttagt
   102481 aataagaacc gaccaacctt attgccattt cgatattagc aggcatagat gcgtcgtagc
   102541 catacatatg gccatatttc ggacgtaata cttcagttac ttttttaata attgcttcgc
   102601 gctgggctcg cgcaaaatca gcatgattat ttgccgtttt attcataaat ttaccaaaac
   102661 tttcttcttt tctgacttta attgtcgtat cccgaagatc attaagaaac tggcgttgaa
   102721 atttaaaatc atcgtgtgaa ccaatattac catgcccgcc aataaaatat ttccagtcaa
   102781 gcatttcaac ctgacgcaaa ttactgtcat ggtaaaccaa cgtatccgat acggcgaagc
   102841 ccatcatcgg cagttggtca ggattcagga gatccgggct gtgagctact ttttcctgtt
   102901 ttagcaacca tacagaatgg tcgtcggtat gtcctgcttt aacaaatcgg tgtaattcaa
   102961 tggtctgctt ttcaaattta aactggtcat cttttttact taaaacctga gtggcgacgg
   103021 gtaagcgact gttcataaat tgcatttttt cagcagtggc tttactggca ataatacgca
   103081 gattcacgcc ttctttcttc gcctcatcgt tccaaaatgg actatcgcca atgtgatcca
   103141 catggtaatg agaataaacc agcgctgtta cgggtaatgg agtcacatca cgaattgcct
   103201 gtaataaata tttaccgcga ccctccggag catcaaacag caaaacccct ttgtctccga
   103261 cataaaacgt agtggaataa aaatagcgtt gaacataata agttctctcg ccaatttttt
   103321 gtaaaatata aggctgagac atatttcttt caaaaaggtt attgagttta tcgcttggcg
   103381 atattatttt ttccgctgaa ggttcaacat aacttgcatt aactgtagac gaatttgaag
   103441 tcgaaatttc cgtttgagca aaaacactac cagatataag agaagaggct agaattgtat
   103501 atattttaat gccttgcata cgtagtcctt tattaatgtg ttgttgattt atagcatctc
   103561 tgaacagact gttattttag atattactac gttacgagat tcatttttct tcgaatatta
   103621 tgtttatctc attcaaaaaa tatgttcatc atttgatggt ttaaataata tctgcaaggc
   103681 ataatactcc acatctttaa aacctgcctc aaaaaatcat tcattagtaa aaaggatatt
   103741 tatatgcaaa acatagctgt ggtttattat tcaggatatg gtcacactaa actggttgct
   103801 gaaaaagtgg cacaaggcgc ccatgcagat ttaatttcga ttgataacga aggaaatatc
   103861 actgagcagg agtgggaaaa actggacgca gccgatgcca ttatcttcgg tgctcccacc
   103921 tatatgggcg gtgcgccatg gcaattcaag aaatttgctg atgccagttc caaagcgtgg
   103981 tttacacgta aatggcagga taaagtcttc gggggtttca ccaacagcgc cagcctgaat
   104041 ggcgataaac aagttacgct gatctatctg caaacgctgg cttcacagca tggcggtctg
   104101 tgggtgagtt taggtcaggc tcctgccaat gtgcttgcgt caaccaggga agatgtaaac
   104161 aatctgggcg gttcggtcgg tttgctggtg caatctccag ccgatgcggg tgcagagcaa
   104221 atccctacgg gcgatctgga tacagccgtg aaatatggtg aacgcgtggc gacaattact
   104281 gcgcgcttaa aatgatgatt gccgaatgtg atgctgacgc gtctatccgg tcttctacat
   104341 ctaaaaagtg ccgtcccctg gtcagtcaga taaagtttta acgctgtatc cgataacagt
   104401 tcaacatgta ccaaaagaaa aaaagccagc ctcgcttgag actggccttt ctgacagatg
   104461 cttacttatt cgcggaacag cgcttcgata ttcagcccct gcgtttgcag gatttcgcgc
   104521 aaacggcgca ggccttcaac ctgaatctgg cgaacacgtt cacgggtgag gccaatttca
   104581 cgacctacat cttccagtgt tgccgcttcg taccccagca aaccgaatcg acgtgccagc
   104641 acttcacgct gtttggcgtt cagctcgaac agccatttga cgatgctctg cttcatatcg
   104701 tcatcttgcg tggtatcttc cggaccattc tctttttcat cggccaggat gtccagcaat
   104761 gctttttcgg aatcaccacc cagcggggtg tctaccgagg taatgcgctc gttaagacga
   104821 agcatacggc tgacgtcatc aactggctta tccagttgct ctgcgatctc ttccgcactt
   104881 ggttcgtggt ccagcttatg ggacaactca cgtgcggttc gcaggtaaac gttcagctcc
   104941 tttacgatgt gaatcggcaa acgaatagta cgggtttggt tcataatcgc ccgttcgatc
   105001 gtctggcgaa tccaccaggt tgcgtatgtt gagaagcgga aaccacgttc cgggtcaaac
   105061 ttctctaccg cgcggatcag ccccaggttg ccctcttcga tcaggtccag caacgccaga
   105121 ccacgattgc cataacggcg ggcaattttt accaccagac gcaagttact ctcgatcatc
   105181 cggcggcgag aggcgacatc tccacgcagt gcgcgacgcg caaaataaac ttcttcttcg
   105241 gccgttaaca gtggtgaata accaatctca ccaaggtaaa gctgagtcgc gtccagcaca
   105301 cgctgtgtgg ctccctgcga taacagttcc tcttcggcca aatcgttatc actgggttcc
   105361 tcttctacta aggccttttc gtcaaaaacc tcaactccgt tctcatcaaa ttccgcatct
   105421 tcatttaaat catgaacttt cagcgtattc tgactcataa ggtggctcct acccgtgatc
   105481 ccttgacgga acattcaagc aaaagcctgg ttccgccgat ttatcgctgc ggcaaataac
   105541 gcagcgggtt tacggatttc cccttgtaac gaatttcaaa atgcaagcgt gttgaactgg
   105601 ttccggtgct acccatggtt gctatttttt gccccgcctt cacttcttgt tgttcccgga
   105661 ccagcattgt gtcgttatgg gcgtaggcac tcaggtaatc atcattatgt ttgatgataa
   105721 tcagattacc gtagccgcgc agcgcgttac cggcataaac aacgcggcca tctgcggtcg
   105781 cgataattgc ctgtcctttg ctgcctgcga tatcaatccc cttgttgccc ccctcagaag
   105841 cgccaaaggt ttcgatcact ttgccctcag tcggccagcg ccaggtggag ataggcgtac
   105901 tggttgatgt actgctgaca gtcggctcgg ttgtgcttgc tgttggtacc gttacaggca
   105961 ctgtgaccgt ggtcgcagtt ggcttgttgt tcggcaacat tttgttagca ctctgttcac
   106021 ccgaagactc agaatacgta attgtcggtt gcgacgcaac agcaacggtg gaattttgtg
   106081 caggcttgat cacaactcct tgctctgctg cgtcggcctg ggtaatggca tttccgcctg
   106141 tgattggcgt accggaagca ttacccacct gtaaggtctg accgacgttc agcgcgtatg
   106201 gtgcctgaat attgttgcgc tgagcaaggt cacggaaatc gttgccagta atccaggcga
   106261 tatagaaaag cgtgtcgcct tttttcacgg tgtatgtact gccgctataa ctgcctttcg
   106321 gaatgttccc atactgacgg ttgtagacga ttcgtccgtt ttccatctgt accggctgct
   106381 gagctactgg ctgcacaggc tggatttgcg gttgttgagt agcctgaatt tgtggctgct
   106441 gtaccggctg aatttgcggt tgctgcgctg tagacgtcgt ccccattttc ggcggcggcg
   106501 taatcaacat accagaattg gtatttgcgg gcgcattgcc attaacggag ctgaccggtg
   106561 ccggtggatt tgaagtgtca gaacagcctg ccagccatag cgaaaccagt gacaatgccg
   106621 caatgcggcg aacggtgaat tttgggcttc ccgcgctcat ttatccccca ggaaaaattg
   106681 gttaataacc agtgacataa ttaccgtgca aggcaccata ctgaacactg gaaaagatgt
   106741 tcacgatacg ctgacttgcg gcaaaataac caggaaaaat ccaggtattt cctcacgttt
   106801 taagccagct cacccttcac taaagggaca aagcgcacgg cctccacggt atcgataata
   106861 aattcgcctc cccgacgacg cacccgtttc aaatactggt gctcctcccc tacgggtaag
   106921 acgagaatcc cgccttcgtc cagctgcgtc attagcgcag ttggaatttc aggcggtgcc
   106981 gccgtaacaa tgatagcgtc aaacggcgcg cgtgcctgcc aaccttgcca tccatcgcca
   107041 tgacgggttg aaacattatg taaatcaaga tttttcaggc ggcgacgcgc ctgccactgc
   107101 aagcctttaa tccgttcaac cgagcaaaca tgctggacaa gatgcgccag gattgcagtt
   107161 tgatatcccg aaccagtgcc aatttccagc acccgcgact gcggcgttag ctcgagtaat
   107221 tcggtcattc gcgccaccat atacggctgc gaaattgtct gcccctgacc tatcggcaag
   107281 gcgatattgt cccaggcttt ttgttcaaac gcttcatcaa cgaatttttc acgcggcacg
   107341 gcggcaagtg cattcagcac ctgctcatcc tgaatacctt gcgcacgtaa ttgatccaga
   107401 agtgcttgta cgcgtctgct taccattgcg tgccaactcc cacgctgttt aaccagtctg
   107461 aaaccacatc ttgcgcgcta tgcgcagtta aatccacatg cagcggcgtg atggaaacat
   107521 agccctcatc taccgcagca aaatcggtcc ccggaccggc atcacattta ccgcccggcg
   107581 ggccaatcca gtacagcgta ttgccgcgcg gatcttgctg cgggatcacc tgatctgccg
   107641 gatgtcgtgt accgcagcgc gtcacgcgaa tacctttgat ttgatccaat ggtaaatccg
   107701 gaacgttaat attaagaata cgcccggtgc gcagcggctc tttacacaat gcgcgcaaaa
   107761 ttgagcaggt taccgccgcg gcagtgtcgt aatgtttatg cccgtcaagc gagacggcaa
   107821 gcgccggaaa acctaaatga cggccttcca tcgcggccgc taccgtaccg gaataaataa
   107881 catcatcccc cagattcggc ccggcgttaa ttccggacac aacaatgtcc gggcgcgggc
   107941 gcatcagagc atttacgcca agatagacgc aatcggtcgg ggttcccatt tgcacagcaa
   108001 tatcaccatt ttcaaaggta aacgtgcgca gggaagattc cagtgtcaga gaattagaag
   108061 cgccgctgcg gttacgatcg ggggcgacca cctgaacgtc agcaaactca cgcaaggctt
   108121 tcgccagcgt ttgtataccg ggtgcatgta ccccgtcatc attactcagc aatatgcgca
   108181 taatcacctg ttgtgttgat aagttccctg acaacgctgg ttgcaaaact tcccgccgga
   108241 agccagaaac ggatttctac ggtgacgtca tcccaccagt tccagcttaa ttgttgcgga
   108301 tacagcagca tcgctctgcg cgcggcttca actttttcac gcaccagtaa agtttgtaat
   108361 tcagtttctt cggcgacagc tgcttgttcg aatgccagcg cttcacgctg agttccccat
   108421 tcgccactgc ccagcaatgc ggcggttatc attagctctt tatcgttgac gcgacgctgt
   108481 aattccgcca gttcttcggt ggttgcaaca aaccagctac cacgtccggc taattgtagc
   108541 gcatcgccgt caacaacttg attaacgtct gcttttttga ggcgctcagc aacaatctga
   108601 ttaaacaacg cactgcgggc tgccgacaac caaaaactcc gtttattgcg atcgcgcacc
   108661 ggagtattgg tttgcgccca gcgcagcgcg ccctgcaagt tgctaccgcc aatcccaaaa
   108721 cgttgggcac cgaagtagtt cggtacacct tttacgcaaa tatcgatcag acgttgttca
   108781 acgtcatcgc gattgctcac ttcgcgcaga accagggtaa aggcgttacc tttcagcgcg
   108841 cctaaacgca gcttgcgctt gtgccgcgca tactccagca cctggcagcc ttccagttga
   108901 aaggcgctca gatcgggcat ctctttgccc ggcacgcgag cgcataacca ctgttccgta
   108961 acagcatgtt tatctttttg cccagcgaag ctgacttcac gggcatgaat tttcaggaat
   109021 ttcgccagtg catccgccac aaaacgggta ttgcagccat ttttgaggat tctaaccaga
   109081 atatgctcac cttcaccatc aggctcaaag cccaaatctt ccaccaccac aaagtcttcc
   109141 ggattggctt tcagcagccc ggtgccttgc ggtttaccgt ggaggtaagt gagattatca
   109201 aactcaatca ttttgttgcc ttaatgagta gcgccaccgc ttcacaggca atcccttccc
   109261 cacgtccggt aaatcccagt ttttccgtag tagtggcttt cacgttaaca tcatccatat
   109321 ggcagccgag atcttcggca ataaacacgc gcatttgtgg aatgtgcggc aacatcttcg
   109381 gtgcctgagc gatgatagtg acatcgacgt tgccgagggc ataacctttc gcctgaatac
   109441 gacgccaggc ttcgcgcaac agctcgcggc tgtcggcacc tttaaatgcc ggatcggtat
   109501 ccgggaacag cttgcctata tctcccagcg ccgccgcgcc aagcaatgca tcggtcaacg
   109561 catgcagcgc cacgtcgcca tcagaatgcg ccagcagccc tttttcgtaa ggaatgcgta
   109621 cgccaccaat gataattggg ccttcaccgc caaaggcgtg tacgtcaaaa ccgtgtccaa
   109681 ttcgcattat gtattctcct gatggatggt tcgggtgagg taaaattcgg ccagcgccaa
   109741 atcctccggg cgcgttacct tgatgttatc cgcgcggcct tcaacaagtt gcggatgaaa
   109801 accgcaatat tccagcgccg aggcctcatc ggtaatggta gcgccttcat ttagagcgcg
   109861 cgtcaggcag tcatgtaaca gctcacgagg gaaaaattgc ggcgtcagcg cgtgccataa
   109921 gccgttgcga tcaacggtat gagcaatggc atttttgccc ggttcggcac gtttcatcgt
   109981 atcgcgcacc ggcgcagcga ggatccctcc cgtgcggctg gtttcgctca acgccaacaa
   110041 tcgcgcgagg tcatcctgat gcagacaagg acgagcggcg tcatgcacca atacccactg
   110101 cgcgtcgcca gcggctttca gacctgccag cacggaatcg gcacgctctt caccaccatc
   110161 aacaaccgtg attcgtggat gattcgccag aggaagttgt gcaaagcggc tatcgccagg
   110221 acttatggca atgacgacac gtttcacccg gggatgcgcc agcagcgcat gcaccgagtg
   110281 ttcaagaatg gtttgattac cgattgagag atattgctta ggacattccg tttgcattcg
   110341 gcggccaaat ccggccgccg gaaccacggc gcaaacatcc aaatgagtgg ttgccatgtt
   110401 aattcccggg ctgatttatc gattgttttg ccccgcagac tgtgcgcgct ttgacgcgtc
   110461 aggcaccaga cgataaaacg tttcgcccgg cctggtcatg ctgagttcat tacgcgcacg
   110521 ctcttcgagc gcctcctggc cgccattgag atcgtcaatt tcggcaaaaa gctgatcgtt
   110581 tcgcgcttta agtttcgcgt ttgtagcttg ctgtgccgcc acatcattat tgacgcgagt
   110641 atagtcatgt ataccgttct taccgaacca cagcgaatac tgtagccaga ccagaatagc
   110701 cagcaacagc agcgttagtt tacccatcct gccccctgaa aaacggcatc ttcatcccat
   110761 gcatccgaag acgactctac atcctctgtt ggggataccg cgacaacgcg ggcaaatgta
   110821 ccacatttgt ccattgttac gtatacccag ggcgtgcaga aaataatctc attattagtt
   110881 acggattgaa ttatgaacag aatagacggg aaagaacaat taacccaata gccacataaa
   110941 cagtgcacca aacataatgc caaccgtcgc cagagtgaaa acaatactgt agcgtagctt
   111001 tccgtccatc aatgaatgca gtgcaatccc caccactaca gcgacgggca tcagcgccag
   111061 aaagaaaggc caggtgtaga taaaaaagag cagcgtgtta gagccataaa tcaacatcgg
   111121 aattgccaac gcgcacagcc acgataaaaa accaaccaca gcgcctggca gcgaccatgt
   111181 ggtgtcttca acctcagtaa ggctgtcgtt atttgttaat gtaatgttgt ggctgttacg
   111241 catatctgat cctgttactt tgacgaaccg ggcatgaaac ccggtggtgt ctcaggatct
   111301 gataatatcg ttctgtctca acagatctaa taattgctgt accaaatttg ttactaattg
   111361 ttcaccattg agatgaattt ctgccgattc aggcgcttcg taaacggaat ctattcccgt
   111421 aaagttgcgc agttcaccgg cacgcgcttt cttatataaa ccttttggat cgcgggcttc
   111481 gcaaatcgcc agcggcgtat cgacaaacac ttcgataaag cgcccttctc ctacgcgttc
   111541 gcgaaccatc tggcgttcgg cgcggtgtgg cgagataaat gcggtcagca ccaccagtcc
   111601 ggcttcaacc atcaaattcg ccacttcacc gacgcgacgg atattctctt tacggtcggc
   111661 atcgctaaaa ccgagatcgc tgcataatcc gtggcgaacg ttgtcgccat ccagcagata
   111721 cgtactgacg ccaagtttat gtaacgcctc ctccagcgcc cccgcgacgg ttgatttacc
   111781 ggaaccagag aggccggtaa accacagcac aacaccacga tgaccgtggt gctgttcgcg
   111841 ttgttgcaga gttactgggt ggctatgcca gacgacgttt tcgtcatgca gagccattat
   111901 ttatctccca gtaaatcgcg cgcaccccaa tgcgggaaat ggcggcgaac cagggcattc
   111961 aattccagtt cgaatgcact gaattcagat ggcgcagcag ttgcctggct aactggttcg
   112021 tgcaccatac cggcacctac ggtcacatta ctcaggcgat cgataaaaat cagcccaccg
   112081 gtaaccgggt tttgctgata acgatctaac accagtggct cgtcaaaggt gagatctacc
   112141 aggccgatgc cgttcagcgg caggttttca acttcgcgtt gggtaaggtt attgatatca
   112201 acctgataac gaatgccatc aacacgagca cgcgtcttct taccggcaat tttgatgtcg
   112261 taactctggc ccggggaaag cggctgttcc gccatccata ccacatccac cgacgcgctc
   112321 tgcacagccg gtaacacttc gtctgccgcc agcagcagat cgccacggct gatgtcgatc
   112381 tcatccgtca gcaccagggt gatcgcttct ccggcaaagg cttcttcgcg atcgccatca
   112441 aaggtcacga tccgcgcgac gtttgattcc acaccagagg gcagcacttt gacacgttgc
   112501 ccgacttcca cacgaccgga tgccagcgtt ccggcgtagc cacgaaaatc gagattcgga
   112561 cggttaacgt actgcaccgg gaagcgcatt ggctgagcat ccaccactcg ctggatctcc
   112621 acggtttcca gcacttcgag cagtgtcgga ccgctgtacc acggcatact ttcactttgc
   112681 gaagccacgt tgtcgccttc cagtgcggag agcggcacaa agcggatatc cagattaccc
   112741 ggcagctgcc cggcaaaggt cagataatct tcacgaatac gggtgaacgt ctcttcactg
   112801 taatccacca gatccatttt gttgatcgcc acgaccagat gtttgatccc caacagtgtg
   112861 gagataaaac tgtgacgacg ggtttgatcg agcacgcctt tacgggcatc gatcagtaag
   112921 atcgccagtt cacatgtcga tgcgccagtc gccatattgc gggtgtactg ctcgtgccct
   112981 ggggtgtcgg cgataataaa tttacgcttc tcggtagaga aatagcggta agccacgtca
   113041 atggtgatgc cctgttcgcg ctcagcttgc aggccgtcca ccagcagtgc cagatccagc
   113101 ttttcgccct gggtgccgtg acgcttactg tcgttatgca gcgatgagag ctgatcttcg
   113161 tagatttggc gggtatcgtg tagcaggcga ccaatcaggg tacttttgcc gtcatcgacg
   113221 ctaccacagg tcagaaaacg cagcaggctt ttatgttgtt gcgcaatcat ccaggcttcg
   113281 acgccgcctt cattggcgat ttgttgtgca agtgcggtgt tcatcttaaa aatacccctg
   113341 acgttttttc agctccatag accccgcctg gtcgcggtca attacgcggc cctgacgttc
   113401 actggtggtg gaaaccagca tctcttcgat gatctccggc agtgtttgtg cgtttgactc
   113461 caccgcgccg gtcagcggcc agcagcccag cgtacggaaa cgcaccatcc gttttttaat
   113521 cacttcgccc ggttgcaggt cgatacggtt gtcatcaatc atcatcaaca taccgtcgcg
   113581 ttccagaacc ggacgttccg cagcgagata cagtggaaca atgtcaatat tttccagcca
   113641 gatgtattgc cagatatcct gctcggtcca gttagagagc gggaagacgc ggatgctttc
   113701 gcctttgtta atttgcccgt tgtagttgtg ccacagctcc gggcgctgat ttttcggatc
   113761 ccagcgatgg aagcggtcac ggaaagagta gattcgctct ttagcgcggg atttctcttc
   113821 gtcgcggcgc gcaccaccga aggcggcatc aaaaccgtat ttgttcagcg cctgtttcag
   113881 gccttcagtt ttcataatat cggtatgttt cgcgctgcca tgaacgaatg gattaatccc
   113941 catcgctacg ccttccgggt ttttatgcac cagcagctcg cagccgtagg ctttagccgt
   114001 acgatcgcgg aactcataca tctcgcggaa tttccagccg gtatcgacat gcagcaacgg
   114061 gaaaggcagc gtacctggat aaaacgcctt gcgcgccaga tgcagcatga cgctggaatc
   114121 tttaccgata gagtagagca tcaccggatt tgagaattct gccgccacct cgcgaataat
   114181 gtggatgctt tccgcctcca gttgccgcag gtgggtaagt cgtttttgat ccataaccgt
   114241 tcctttgcaa taccgctatt ttcttgccat cagatgtttc gactataggg agcgtaagag
   114301 aacgaatgaa attaccaatt agaatgagta gttccttaac ggaataacga tttggcaaag
   114361 ctaatatcaa aaagtgctta aggcaccgga tttcgggcgt ttaggaagat ttgaaattgt
   114421 tttagcgcag cggcagtttc atactatggc ggtaaaaaaa tttgcatggt atttaaggac
   114481 tcactatgtt ttccgcattg cgccaccgta ccgctgccct ggcgctcggc gtatgcttta
   114541 ttctccccgt acacgcctcg tcacctaaac ctggcgattt tgctaatacc caggcacgac
   114601 atattgctac tttctttccg ggacgcatga ccggaactcc tgcagaaatg ttatctgccg
   114661 attatattcg ccaacagttt cagcaaatgg gttatcgcag tgatattcgg acatttaata
   114721 gtcggtatat ttataccgcc cgcgataatc gcaagagctg gcataacgtg acgggaagta
   114781 cggtgattgc cgctcatgaa ggcaaaacgc cgcagcagat catcattatg gcgcatctgg
   114841 atacttacgc cccgctgagc gatgctgacg ccgatgccaa tctcggcggg ctgacgttac
   114901 aaggaatgga tgataacgcc gcaggtttag gtgtcatgct ggaactggcc gagcgcctga
   114961 aaaatacgcc taccgagtat ggtattcgat ttgtggcgac cagcggcgaa gaggaaggaa
   115021 aattaggcgc tgagaattta ctcaagcgga tgagtgacac cgaaaagaaa aatacgctgc
   115081 tggtgattaa tctcgataac ttaattgttg gcgataaatt gtatttcaac agcggtgtaa
   115141 aaacccctga agcagtaagg aaattaacgc gcgaccgggc gctggcaatt gcccgcagcc
   115201 atggaattgc cgccaccaca aatccaggtt tgaataaaaa ctatccgaaa ggcaccgggt
   115261 gttgtaatga cgcagaaata ttcgacaaag ccggtattgc tgtactttcg gtggaagcga
   115321 ctaactggaa tcttggcaat aaggatggtt atcagcaacg agcaaaaaca gccgcattcc
   115381 ctgcgggaaa tagctggcat gacgtaagac tggataatca acagcatatt gataaggcac
   115441 ttcctggaag aatagaacgt cgctgccgtg atgttatgcg gataatgcta ccgttggtga
   115501 aggagctggc gaaggcatct taatgggttt gaaatgatta ctcccttgcc tgcaggaaat
   115561 caatgccacc agaaacagag tataaaaaag gggtgcagga ggccaaacca tcacaattca
   115621 gtacgcgggg ttttaccccg cgtggtggct acttcttcga ttcgtaagcg agaactgcct
   115681 taaactccat accacgttct ctgatactca actcacacaa cgagtcgcct accatcaacg
   115741 tgaatcccag tactgtacaa cacagtacga tgattgccac aagggcatat tttgtcagca
   115801 tgtcttgcct ccctgcaaag aagagactaa catccgaatt gctacgttcg aacgcgagcc
   115861 tcaggttgat agaaatatcg cctggggctt ttgtccatct ggaaccttgc gaatgcttaa
   115921 cgccagacag cctcaagcac ccaatgccat tctatacctg ttaattttcc ctgcgatgtt
   115981 cacctttaaa tgccggaatg ctgctcgcaa aaaataaaaa cgcctccatc atttctgaca
   116041 gaggcgttta atttatccgg caatatttac ccttcgtgta atccacattc cctttttaag
   116101 ccaaagaaac gcgtttcttc ttccgccatg ccgggttccc atttacgggt tgtatgggta
   116161 tcgcccaccg ataaatatcc ttcatcccat aatgggtgat atttcaggcc atgtttttgc
   116221 aggtactgat aaatagttcg gttatcccag tcgataatcg gcagcacttt aaatacgcca
   116281 cgctgaattg ccagcaccgg taaattggcg cggctgccgg attgttcacg gcgcaggcca
   116341 gcaaaccagg tttgcgcatt cagttctttc agcgcccggt tcatcggttc gactttgttg
   116401 atgtcattgt acttttcaat gccttcaacg ccctgctccc acagtttgcc gtagcgtgct
   116461 tcctgccagg cggcgctttc ggtagcacga tacactttca ggttgagctt gagtttgtcc
   116521 gttaactcgt caataaagcg gtaggtttcc gggaacagat agccggtatc ggtgaggatc
   116581 actggaatat ccgggcgaat ctgattcacc agatgcaggc tcaccgccgc ctgaatgcca
   116641 aagctggaag aaagtacata ttcaccgggc agattatcca gcgcccaggc tacgcggcct
   116701 tcagcgtcca gtttttccag ttgggcgtta gtttccgcca gcgccagaat ccggtctacc
   116761 tttggcagtt cgttcagggc gtttagatcg agtttggaca taagttcctc actgtttgcc
   116821 ttgcctgatg caacgctcac acgtcttatc aggcctacaa gaccgggctg atggttaatc
   116881 ccacaaatcg cgcgccggat cgagcaccgg gcgaatgatg cccgcacgca ccgtaaagtc
   116941 gccgaagcct tcacccgctt cgcgctcttt cgcccagcgc cctatcagtt catcaagcga
   117001 cgccaggatt tccggctcgg tgatgttttc tttatacatc cgtgggatac gtgtcccaat
   117061 gcggttgccg ccaagatgca ggttgtagcg acccggcgct ttccccacca gacccacttc
   117121 cgccagcatc gcgcgaccac aaccgttcgg gcagcctgtt acacgcatca cgatatgctc
   117181 atcgctgaca ccatgtttcg ccattaaatt atcgatgttg tcgataaaag acggcaggaa
   117241 acgctccgct tccgccatcg ccagcgggca agtcgggaat gacacgcagg ccattgagtt
   117301 ttcacgctgc ggcgtgacgg cattcattaa cccgctttct ttggcgatct tctcgatctt
   117361 cgctttctcg ctttccggca cgccggcgat gatcagattc tggttcgccg taatgcggaa
   117421 atcacctttg tggatcttcg cgatctccag caagccggtt ttcagcgggc gccccggata
   117481 atcaagaatt cgaccatttt cgataaacag cgtcaggtgc cagttatcat caatgccctt
   117541 aacccagcca atacgatcgc cgcgtccggt aaactcatac gggcgaatcg gctcgaattt
   117601 gatccccgcg cgacgttcaa cttccgcttt aaacgtctca acccctacgc gctccagcgt
   117661 gtatttggtt ttggcatttt tacgatcggt tcggttaccc cagtcacgct gagttgtcac
   117721 gacggcttcc gccaccgcca gcgtatgctc cagcggcaga tagccaaact cactcgccgt
   117781 gcgggcgtag gttttcttgt tgccgtgttc gatggaaagc ccaccgccca ccagcaggtt
   117841 aaagcccacc agcttgccgt tttcggcgat cgccacgaag ttcatgtcgt tggcgtgcag
   117901 atcgatatcg ttctgcggcg ggatcactac cgtggttttg aacttacgcg gcaggtaggt
   117961 ctgaccaagg atcggctctt catcagtagt ggcgactttt tcctgatcga gccagatctc
   118021 cgcatacgcg cgggtacgag gcagcagatg ttcagaaatt ttcttcgccc attcatatgc
   118081 ttccgcatgc agctgcgact cgtaagggtt cgaggtgcag agtacgttac ggttcatgtc
   118141 gttggcggtc gccagcgcat caagaccgac cgagtgcagc atctggtgca ccggtttgac
   118201 gttctttttc agaatgccgt ggaactgaaa cgtctggcgg ttggtcaggc gaatgctgcc
   118261 atagatggtg ttttcaccgg caaatttgtc gatcgcctgc cactgtttag tggtaatcac
   118321 cccacccggc agacgacagc gaagcagcat cgcgtggcgc ggctccagct tctgttcagc
   118381 acgttcggcg cgaatgtcgc ggtcatcctg ctgatacatg ccgtggaagc ggatcagcag
   118441 gaagttatcg cccttaaagc cgccggtcag accgtcgttt aaatcttccg caatggtgcc
   118501 gcgcaggtag ttgctttcaa gcttcatgcg ctcggcgtct gtcagttttc cttcgaccac
   118561 taaaggccct ggatgttttt cgctcattag tagacatctc gctgataacg gcgctctacg
   118621 cgcagctcac ttaaaaattc atccgccgct tcggtgtcca tgccaccaaa ttcggcaatc
   118681 acttccagaa gtgcctgctc aacgtctttc gccatgcgat tagcgtcgcc gcagacataa
   118741 atgtgggcac cgtcattgat ccagcgccac agctctgcgc cctgttcgcg cagtttgtct
   118801 tgtacgtaaa ttttttcttt ttgatcgcgc gaccaggcga gatcgatgcg cgtcagcacg
   118861 ccttctttga cgtaacgctg ccattccacc tggtagagga aatcttccgt aaagtgtggg
   118921 ttgccaaaga atagccagtt tttacccggc gcttcgtcgg cggcacgctg ctgcataaag
   118981 gcacggaacg gcgcgatgcc ggtgccaggg ccaatcatga tcaccggggt ttccggattg
   119041 gttggcaggc ggaagttgtc gttatgttcg ataaatacgc ggacttcacc ctcttcttcc
   119101 acacgatccg cgaggaagct ggaggcacca ccggcacggg cgcggccttc cacgtcgtaa
   119161 cgcaccacac caacggtaac gtgcacttcg ttctcgactt ccgcctgcga ggaggcgatg
   119221 gaatacaggc gcggggtcag tgggcgcagc agattaatca gcgcttcggc atccagttgc
   119281 gccggagaga aacgcaccat gtcgacaatc ggcgtcgtcg cggcgtaatg ctgtaacttc
   119341 gctttatcgc ccaccagcgg cagcagcgtt tcgctgcggg taagcgtggc atagttctca
   119401 acaatgttgg cggtgttgac ggtcagttcg aagtgccact gtagcgcttc gttcagaggc
   119461 aacgttttgc cctcgacggt gacaggttca tcgcctttca gccacagcag ttcgacaagt
   119521 tctttcacca gtgccggatc gttttgatac cagacgccca gcgcgtcacc cggctggtaa
   119581 cgcaggtcag agtcacctaa gtcaatttca atgtgacgaa cgtctttttc agagttacgc
   119641 ccggtaattt tctggttaac agagaggctc gccaccagcg gcgcgtcttt gctatacggg
   119701 ctggtgtgga tttcatttac cgtgccagta gcgacggatt gcgaaggtgc cgcgacaggc
   119761 gcacgcgatt taagcgcatc aaccacgcgg gcgcgccact cgctggcagc agcctggtat
   119821 tcaacgtcgg catcgacacg gtcgagcagg cgttcaccgc ccagttccgc cagcttactg
   119881 tcaaaatctt tcccggactg gcagaaaaat tcataagagc tatcgccgag gctaaacacg
   119941 gcaaacgcgg tgttttccag ctttggcgct tttttggaga acaggaactt atgcagcgcg
   120001 acggcttctt ccggcggttc cccttcccct tgcgttgacg tcaccacgat aagcagtttt
   120061 tcgctggcga tttgtttgaa tttatagtcg cccgcgttca ccagcttaac gttcagtttt
   120121 gccgctaata aatcatcgcg taatgcttca gcaacccgac gcgcattgcc agtttgcgag
   120181 gcggagataa tagttatacc cggcatttct gcggcgggcg ctggcgtcgc tgcaagcgca
   120241 gcaggctgct ggttgagcac gccccagaaa tagccagaaa cccaggcaag ctgggtagga
   120301 gttaaatcgg tcgtggccgc ctgaaggcgt gccagttgct ccgggttcaa cggaagcaac
   120361 gcggaaggtg ggacctgtgt cgtcatgcgt cgttatgttc cagtaagcaa agctgtttct
   120421 gcgccctgtc agcgcccata aaacagaaga gaaggtaagg ttaacggggt gaacggtgtg
   120481 gattaaagac gggatagcga taactaataa ccaaatcgac taacctgttt tagcaatagt
   120541 ctttaacaac aaaatagatt aaccaaccca atgaaaaaca aatgaatatt gcccatcaat
   120601 aagataaatc agcgattttg cgcaacaaag tcgttttaga taatgcgaaa aaacagcctt
   120661 tccggtactc tacggcggtt ttatcgtcat gtagagaaat tatgatgtcc accacgttat
   120721 ttaaagattt caccttcgaa gccgctcacc gcttgccgca cgtcccacaa gggcataaat
   120781 gtggtcgcct gcacgggcat tcctttatgg tgcgactgga aattaccggg gaagtcgatc
   120841 cgcatacggg ctggattatc gatttcgctg aactgaaagc ggcgtttaaa ccaacttatg
   120901 agcgcctcga tcaccattat ctcaatgata ttccaggtct ggaaaaccca accagcgaag
   120961 ttttagcaaa atggatttgg gatcaggtta aacccgttgt gccgctgtta agtgcggtga
   121021 tggtaaaaga aacctgcacc gcaggttgta tctatcgcgg cgaatgataa gagtgtgtcg
   121081 gcggtcaatt tcccttaagt aacgctatgt tagggtgttg tgttctggat atctggggca
   121141 tgacatggaa gacgactgcg acattattat tatcggtgcc ggaattgctg gcaccgcttg
   121201 cgcgttacgc tgcgcgcgag cgggtttatc cgttttgtta ctggaacgag cggagattcc
   121261 cggcagcaaa aatctttccg gcgggcgttt atatacccat gcgctcgcgg aactcctccc
   121321 gcaatttcac ctgaccgcgc cccttgaacg acgcatcact cacgaaagtc tttctctgtt
   121381 aacgccagat ggcgcaacga cgttttccag cttacagccc ggcggtgaat cctggagtgt
   121441 attacgtgca cgattcgatc cgtggctggt tgccgaagcc gaaaaagaag gtgtcgaatg
   121501 catccccggt gcgacggtag atgcactgta tgaagaaaac ggcagggtgt gtggtgtcat
   121561 ttgtggtgac gatattcttc acgcccgtta tgtggtgctg gcagaaggtg ccaacagcgt
   121621 cctggcggaa cgccacgggt tagtgactcg tcctgctggc gaagcgatgg cattgggaat
   121681 caaagaagtg ctgacgctgg aaccatccgc tattgaagaa cgttttcatc tggagaataa
   121741 cgaaggcgca gcgttgttgt tcagcggcgg gatctgtgat gacttacccg gcggcgcatt
   121801 tctttatact aatcaacaaa cgctctcgtt agggattgtt tgcccgctct cctcccttac
   121861 gcaaagtagt gttccggcaa gcgagctgct gactcgcttt aaaacgcatc cggcagtgcg
   121921 cccgcttatc aaaaacacgg aattactgga gtatggtgcg catctggtgc cagaaggtgg
   121981 cctgcgcagt atgccggtgc aatacgccgg taacggctgg ctgctggtgg gcgatgcgtt
   122041 gcgcagttgc gtcaataccg gaatttccgt gcgcggcatg gatatggcgc taactggcgc
   122101 gcaggcggcg gcacaaacgc tgataagcgc ctgccaacac cgcgagccgc aaaatctgtt
   122161 tccgctttat catcacaacg tagagcgcag cctgctgtgg gatgttctac agcgttatca
   122221 gcatgttccg gcgcttttgc aacgtcctgg ctggtatcgg gtgtggcctg ggttaatgca
   122281 ggatatttcc cgtgatttat gggatcaggg gaatacacct gttccaccgc tgcgccagtt
   122341 gctctggcgt catttacgtc gtcacggcct gtggcatctg acgggcgatg ttatcaggag
   122401 tctgcgatgt ctgtagcccg taatctctgg cgcgctgctg atgcgccgca cattgttccg
   122461 actgactccg ttgagcgcca gacggcacaa cggttgatta acgcctgtcc agcaggtctt
   122521 ttttcgctca cacctgaagg tggcttacgt gttgattatc acggctgcct ggagtgtggc
   122581 acctgccgtt tgctgtgcga cgaatcaaca ctacaacagt ggcgctatcc gccttccgga
   122641 ttcggcatca cctaccgctt tggataaata ataaggataa tttatgcccc tcttacacct
   122701 gctccgccag aatccggtga ttgctgccgt taaagataat gccagcctgc aactggcaat
   122761 cgactctgaa tgccagttta tttccgtgtt gtacggcaat atctgcacca ttagtaatat
   122821 cgttaaaaag attaagaacg ccgggaaata tgcttttatt catgttgatt tgctggaagg
   122881 cgcgtcaaat aaagaagtgg tgattcagtt tttgaaactg gtaaccgagg cggacggaat
   122941 tatcagtacc aaagcctcaa tgctgaaagc agcaagagcg gaaggttttt tctgtattca
   123001 tcgactgttt attgttgatt cgatttcgtt tcacaacatt gataagcaag ttgcgcaatc
   123061 gaatccggat tgtattgaga tcctgccagg ctgcatgcct aaagtgctgg gctgggtgac
   123121 ggagaaaatc cgccaaccgc tgattgctgg cgggctggtg tgcgatgaag aagatgcgcg
   123181 taatgcgatt aacgcgggtg ttgtggcgct ttccaccacg aatactgggg tctggacgtt
   123241 agcgaaaaaa ttgctttgac gggataatcg taacaagttg aatttggtgt gatttgtagg
   123301 ctgcacgcca catccgacat tcagcgcctg atgcgacgct tgacgcgtct tatcaggcct
   123361 acaagtcccc agcccagaac catcggcagg atcatccggc agcacgttat tggcaatctg
   123421 cgtgaatgtt tgtcaccagt gcctccagca ccactttcca gtcatcaact acgccaacat
   123481 ctgcctgtga aaataccgct gcactggcgt catgattaat cgccaccaca aacttgctat
   123541 tgcgtacgcc cgccattaac gctgctgcgc cggaagcgcc aacaacaata cacacctcag
   123601 gtgccagcag atgtccggaa ataccaatca ctttttcggc atcaacgcca ccgttcatca
   123661 ctcgtgcccg actgtagccc acttcggctc ccatcttttc tgccagcata gcgatttcct
   123721 ggttatctgc ctctccgccc tgccccacca ccagcacccg tctggcttca gctaatgggt
   123781 cgcggataac atttttcaga ttttctatgc taaccagcca gtcgggaagc acacctggga
   123841 caatgttcag ttgctgcatc ccagagggca acgtggcgtt tttatctgct cccgcctgac
   123901 gtgccagcga aaggcatagc gggcgtttgt ctgtttgcag cgtcgccgtc aacgcatttc
   123961 cccagtggga tttgcgcacg cttacggttg gaatatctaa cgaagtcacc tggcagatgc
   124021 ttgcaccatg taaacgccag gccagccggg tcgacagttc atcgccaaac gcgcccggag
   124081 gaaaaaggac aacgtccgca ggcgttcgtt gccactgttc caccagtgca tccagcacct
   124141 gttccgcaac catcggctgt ggttctattt gccaatgtgc cagggtacaa ccgctgaaat
   124201 cctgcgccgc cagccagctc gctattgcgg catggtcctg atttattgtc acaattacga
   124261 tattcatggc tgcatccttt ggcgtaaata gtcctgccat agcttttgcg ctttttctgc
   124321 taccgtttgc ccaccaatca gcgtcgctcc gcgtcgttgc tctgctcttg ccagttgcag
   124381 acactgcatc gctggcaatt cgacagcaac agttttacgg ataattgctg ctttccccgc
   124441 agccattcgc tggcgcattc ccggaactgg caaggccact tcaccgcact gacgcacggc
   124501 aatcaccgca ggcaagcgaa cccggcaaca gcgcacccca tgttcagtac gctgttcgag
   124561 ggtgataaac ggtgcgtcga gagtaaagcg ctccacctgg gtgaagcagg gccagaccag
   124621 catttccgcc agcaaaaatg gcgtttgccc attctgccct tcgctgcttt ggcagccggt
   124681 aattatcaga tccagcggat tctgacgctg ccattcggca atatggcgag cgacaaattc
   124741 cggcgcaaag cgcagatctg ccgccgtctc cagcaataca gcttcctcaa acccaagagc
   124801 catgagatag cgcagccagt gcaacgcccg ttcatccccc atgctcaacg cggttaaaga
   124861 catcggcgta ccgttttttc tctgcgccaa cagcagcgca gctgcggcct gttcatcagc
   124921 accgagtaaa cttcgcagaa gcgaaacatc cggtccgcta ttaccctgag ccgccgcctg
   124981 ccactctttt tccgccagca ttccggcatc cggttcggct ttaaacgcta acagaatgtt
   125041 cattcgcacc tcctacattt cccgccgcca ccagcgggag tgctttggtt tctggtgccc
   125101 atagccaggt cacaacaaaa ccaaccaaca acactgccgc caggagtaat aaggtggctt
   125161 gcattcccca ctgcgccagc acccacggca gcaggccagt acttaccgcc gcccccaacc
   125221 gactcatggc ggtggcaaaa ccgacgccca gcgagcgaat gtcagtagga aaactttccg
   125281 caggcaaaat gcccaccaga ttactgactg ccgaaatggt ggtgctgaag agaacaaaaa
   125341 gcagcagcgt taatgaactg ccggaaggca aacaggccat cactaccagc gttgccgcca
   125401 gcagcaaaaa acttcccagc aaaaacttgc gatgtgccag caggtgcgtc agaactaatc
   125461 ccagcagcgc gcccacaatt aacaacgcat taagcatcag actggcagtc agcgcatctt
   125521 ccagtccaat agtctgggcg atagttggca gccaggtata aatcacaaac catgggatta
   125581 cgaggcagac aaagaagacg ctgttaaacg ctgtgcgccg ccagtagcgc gaagagaaca
   125641 aggttttgat gtgtttatgg gtcgccgttg ccacttcatc gcccagtaaa acatgcgggc
   125701 caaaatagcg atgaacgata gcgtgagctt ctgcaaaacg cccctggcgc agtagccagc
   125761 gtggcgattc cggcgtgccc caacgtagca gcgtaatcag caaggctggt aacgccgctg
   125821 atgccagcag ccagcgccag gcctccgggc tttcggaaat aaagtgatgt ccggcaatac
   125881 ttgccagcac atagcctacg gtccacacca cactgaatgc gcccagcaaa ataccgcgat
   125941 ggcggcgcgg ggaaaattca gccagcaagg tgtgaccgac tgagtaatcg cctcccagac
   126001 caatgccgat caaaatgcgt aatccaataa gatgctctgg cgtggtggca aaaaattgca
   126061 agaacgaagc gagcgtaatc agcataaaac tgaaggtgaa gattttttgc cgcccgatat
   126121 ggtcggagat ccaccccaaa accaggctgc caagaaacaa accaagtaac gccgagccgc
   126181 cgatcattcc cgccataaac ggcgtcagtt gcatggcggg cgtaagctga ataatggcat
   126241 aaccaatgac gccgagaaca taaccgtcgg tcaggtgtgc gccgaaagtg agcgcagcaa
   126301 ttcgacagtg aaaacggtta agcggtaaat catccattcg caccggtgaa gtgttcatct
   126361 ttaccccttc attgtccggt aataagaacg gcttctcgcc tgagaagccg aaaaggcaac
   126421 gcaccgtcat cgcggaacgc tgcctgacac attatttttc aatcggatag atagtacccg
   126481 tgttcataat gccattagga tcgaactgct ttttcagccc ttccagcaac gcccacgcgc
   126541 tgccgtgttc cagtttgctc cagtgaacgc gatgtttacc gataccgtgg tgatgcacca
   126601 tcgaaccgcc gaggcgaatg gtttcttcgc agatgatttt gttgagcgga ttgtggtact
   126661 tgtcgatttc ctcttccggc ttacagtcaa cgacgttgta gtcgtagacg aagtacatgt
   126721 tggtgccgtt ctgatagcta tgagaggagt gaccgcccag catggtgatg tcgtcggcgt
   126781 gcgggaactc ggtacgaata cggttaataa cgctttcgta gatttcgtga atgcagctcc
   126841 agcagccgga cacttcagtg gtaaagccca tgttgccggt tttgaggatc tgcacacgtt
   126901 cggcagccac tttatccggt ccccagttca ggttgttaaa ccaggtttcg atcagcttgc
   126961 tgtccacgcg ctggcactgc gggtagcgcg ccacgatttc agcaatccct tcacccgtcg
   127021 ccttcgcaat gcgagggtta ccttcagcca taaagatcag cacgcatttg ccgtcggcaa
   127081 aatgggtgaa gtgttgggtg ccatcttcag catcatacaa acgagcaatc gacggacgat
   127141 acccttccac catgatttca cgcaggatgt tgaagccggt tttcatatct tccaggatat
   127201 agccgtagaa gagattgttt tccggcgtaa atttgaagat tttcactgtg acttcagtga
   127261 tatagcacag tgcaccttcg ttgccgatga tgatatgacg aatgtccggg ccagccgcgc
   127321 gacgtggcac ttttttaatg cgtgtgacgg tgccatctgc cagcaccgct tccagaccaa
   127381 cgaccatatc ttcgattgcg ccgtagagtg tggagaactg cccgatactg cgggtcgcca
   127441 ccaagccgcc catctgcgcc agcggctttg actgcggaga atgccccgtg gtgtaacctt
   127501 tttcgcgcaa tgcgttttcc agcacctcca gcggaacgcc acattgcgcc gtggcctgca
   127561 tattctcaat atcaatatta atgatttgat tcatggcgga gccgtcgagc accaccgagt
   127621 tttccacaac ggtttccagt ccaccttcgg tggcggaagc accggtacgt ggcacaccgt
   127681 taattttgtg cgcattcata aaattcagca cacgggatac ttgttctgtg gaaccgagtt
   127741 ttacgaccgc tgccggaatc ggcaaagtat aaattccatg aatatccgga aatttacgaa
   127801 aacggtcaat actgtttttc tttaataccg tttcatcggt aataacgcga tctgcaccaa
   127861 caatttcctt tagctggtcg acaatcgcta cgcgagataa agacataata attccttcct
   127921 gataataaaa atggaatagt tattaataag agaaaacaga aaccaccgtt atgaattagc
   127981 gcactaaata accgccatca accactaata aatgtccgtt gacataattc gatgccggac
   128041 ttgcgaggaa tacggctgcc cccattaaat cctgagtatc accccaacgg tttgccggaa
   128101 tatgatcaag aacacgctgg ttagtttctg gattactacg ggtcgccagc gtaatatcgg
   128161 ttgcataata accaggagca ataccattca cctgaatatt atattggcct aattcatcgc
   128221 aataggcttt ggtgaatccg gcaagagcat gtttagtggc agaataagca ggtgaccatt
   128281 gaccacctaa gtaagagaac aatgaacaga tattaatgat tttaccgctt ttctgcggga
   128341 tcataatttt tgccgcttcg tagcttaact cgaatgcggc ggtcaggttc acgtcaatca
   128401 tcgggtccca gtcggcacga ccaaagtcca gcaccttatt cagcttacaa ataccggcat
   128461 tattgaccag aatatcgacg gtaccgaagc gctcacagca ggcagcgata atcttctgcg
   128521 gcgcgccttc tgcggtgata tccacctgca taaaatcaac ttcaacgccc tgtttttcaa
   128581 tcatttcctt tgtttcgccg ttatctttga cgaaactagg aataaagaca tttgcgccag
   128641 ctttggccaa cgccatggca aatgcctggc ctaaaccgct attcccgccg gtaacaattg
   128701 ctgttttacc tttcagggag aaaaaatcca ttgagaacgc attgagagat tcgattgaca
   128761 tagttagctc caatttccgt aaggcaaaaa aaaagaaagg taacttcccc cgcgagaggg
   128821 aagttacctt tctcattatc tctggtaact ggagataatt tttagcataa ggacataact
   128881 gctaatgtga tcgtaatcac agtgtgatgt tcgtattgtc aaataattta aaaaagcaga
   128941 agcgtgatta ctctcacaca acacctctgc tttccatgtt atttcttatt gcaattacta
   129001 gagacctgag aaaagtaatc cacctgaaag ggcggcttac ttttctcttt tttttgtcta
   129061 ttacaaatgg gaatacgata tgcaacacaa ctcatatcgc cgttggataa ccctcgcgat
   129121 aattagtttt agcggcggcg ttagtttcga cctggcttat ttacgttata tttatcaaat
   129181 tcccatggca aaatttatgg gattcagcaa taccgagata ggtttaataa tgagtacctt
   129241 tggtattgcg gccattattt tctatgcccc tagcggcgtt attgccgata aattttcaca
   129301 tcgcaaaatg attacttccg cgatgatcat taccggatta ctgggtctgt taatggcaac
   129361 atatccaccg ctgtgggtaa tgctctgtat tcaggtcgcc tttgcgataa cgacgatttt
   129421 aatgctgtgg tcggtgtcga ttaaagccgc atcgttgctg ggcgatcata gcgagcaagg
   129481 gaaaattatg ggctggatgg aagggctgcg cggcgtcggt gtaatgtcgc tggcggtgtt
   129541 taccatgtgg gtcttttctc gctttgcacc ggatgacagc gccagcctga aaacggtcat
   129601 tattatctat agtgtggttt acattctgct gggcattttg tgttggtttt ttgttagcga
   129661 taacaacaac ctacgcagtg ccaataacga agaaaaacag tcattccagc ttagcgacat
   129721 cctggccgtt ttgcgcatca gcactacctg gtattgcagc atggtgattt ttggtgtctt
   129781 caccatctac gccattctga gttactccac caactatctg accgaaatgt acggcatgtc
   129841 gctggtggcg gcgagctaca tggggattgt gatcaacaaa atcttccgcg cgctgtgcgg
   129901 cccacttggc ggcattatca ccacctacag taaagtgaaa tcccctaccc gcgtggtcca
   129961 aatcctttcc atcatcggtt tgctggcgtt gacagccctg ctcgtcacga actctaaccc
   130021 gcaatcggtc gcgatgggga ttggcttgat tttattactg ggattcacct gttacgcctc
   130081 acgcgggctg tactgggcct gccctggcga agcgagaaca ccgtcttaca ttatgggcac
   130141 cacggtaggt atttgttcgg tgattggatt cctgccggat gtcttcgttt acccgattat
   130201 cggctactgg caagacaccc tgcccgctgc agaagcctat cgcaacatgt ggctaatggg
   130261 catggcggcg cttggcatgg tgatcatctt tacctttttg ctgttccaaa aaattcgtac
   130321 tgctgatagc gcccccgcaa tggctagcag caagtaagcc aggaaaatta caggagaaaa
   130381 atcatgtcga aaaaatacat catagggatt gatggcggaa gtcagagcac aaaagtggtg
   130441 atgtacgatc tggaaggtaa tgtggtttgc gaaggcaaag gcttattgca gccgatgcac
   130501 acgccagatg ccgataccgc agaacatcct gacgatgatt tatgggcatc actatgtttt
   130561 gccagtcacg atttgatgag ccagtttgcc gggaataaag aagatattgt cggcattggc
   130621 ctgggctcaa tccgttgctg ccgtgcgcta ttgaaagccg atggtacgcc agccgcgccg
   130681 ttgattagct ggcaggatgc acgcgttaca cgcccttacg aacacactaa tcctgacgtg
   130741 gcctatgtca cctctttttc gggttatctg acacatcgct taaccggcga gtttaaagac
   130801 aatatcgcca actattttgg tcagtggccg gtggattata agagctgggc atggagcgaa
   130861 gatgctacgg taatggaaaa gtttaatatc ccccgccaga tgctttttga cgtgcaaatg
   130921 ccgggcacca ttcttgggca tatcacacca caagctgcgc tggcgacaca tttcccggct
   130981 gggctgccgg ttgtttgtac caccagtgat aaaccggtag aagctctggg agccgggtta
   131041 ctggatgatg aaacggcggt aatttctctt ggcacctata tcgcgttgat gatgaacggc
   131101 aaagcactgc cgaaagatcc ggtggcgtac tggccgatta tgtcttctat tccgcaaaca
   131161 ttgctgtatg aaggttacgg tattcgcaaa ggcatgtgga cggtgagctg gctgcgcgac
   131221 atgttaggcg agtcgttaat tcaggatgcc aaagcacagg atctttcacc ggaagatttg
   131281 ctcaacaaaa aagcgtcttg cgtgccgcct ggctgtaatg gtctgatgac ggtgctggac
   131341 tggctgacca atccgtggga accgtacaaa cgcgggatta tgatcggttt tgattccagc
   131401 atggattacg catggatata tcgttcgata ctggaaagcg tggcgctgac gctgaagaat
   131461 aattacgaca atatgtgtca tgaaatgaat cactttgcaa agcatgtgat cattactggc
   131521 ggcggttcga acagcgatct gtttatgcag atttttgccg acgtgttcaa ccttccggca
   131581 cgccgaaacg ccattaacgg ttgtgcaagt ctgggggctg cgatcaatac ggcggtaggt
   131641 ctggggctat acccggatta cacaacggct gtcgataaaa tggttcgcgt gaaagatatc
   131701 ttcataccga ttgagagcaa tgccaaacgc tacgacgcga tgaataaagg cattttcaaa
   131761 gacctaacca aacatactga tgtgatcctg aaaaaatcgt atgaagtgat gcatggggaa
   131821 ttggggaatg cggattcgat ccagagctgg tcgaatgcgt aagtgagata aacagtgccg
   131881 ggtagatgat taatcccggc atattcacgt ttccactaca aaataccggg taaccactgc
   131941 tgaatattgt tctctcctga gcagcgttta tgctttaatt gctaaaccga tttaattagt
   132001 ttagcaatta gtatattgga gcctttatga gcacaagagt atgggtactc ggtgatgcgg
   132061 ttgttgattt attacccgaa agccagggga gactactaca gtgtcctggt ggggcgcctg
   132121 ctaatgttgc agtcggtatc gcaaggctgg gggggaaaag tgcctttatt ggcaaagttg
   132181 gcgatgatcc tttcggtcgc tttatgtatc aaacactgag tacagaaaat gttgatacac
   132241 gttatatgtc tcttgatcct caacatcgca cctcaattgt ggctgtagga cttgatgagc
   132301 aaggagaaag aaactttacc tttatggtac gcccaagtgc cgatcttttt ttacaacctg
   132361 atgaccttcc tgcatttggg ccgggtgaat ggctccatct ttgttccatt gcgctcagtg
   132421 cagaaccttc ccgaagtacc gcatttctgg ctatggagaa aatacgtcag gctggcggaa
   132481 acatcagttt tgatcccaat atccgcagcg atctctggca gagtgaagcg ctgttaagga
   132541 aataccttga tcgtgcgctt tcgctggcga atatcgctaa attgtccgaa gaagagttgt
   132601 tattcatcag tgacgaaagc caggttcagc aaggcgcata ttcattagta caacgttatc
   132661 cgttgacttt attgcttatt acacaaggaa aaaatggcgt acttgtgtat tttcaggggc
   132721 agtttatcca ctatcccgcc aaacctgttt ctgtcgtcga tacgaccggg gcaggagatg
   132781 cttttgtcgc tggattactt gccggtctgg ctgattctgg aataccaaca aataccagac
   132841 agcttgaacg aatcattgca caagctcaga tttgtggtgc tctggcgacc acggctaaag
   132901 gcgcgatgac cgccttaccc cgacaacacg atctcccttc acaatagtga tcctgctgtt
   132961 gtatctgtaa cccgatttgt cgtgcctgtc acatttacta aatcggttta gcgaaaataa
   133021 ttgctctggc taaaaagtca gctttattat caacacctaa accggtttag cattttagca
   133081 atttttataa ttctctgatg ggacgcgaca aattatgtat aaaaaaacaa ctttggcagt
   133141 gttaattgct ttgctgaccg gtgctacaac ggtacatgcg caaacggata ttagcagtat
   133201 cgaatctcga ctggcggcgt tggaacaacg tttaaaaaat gcggaatccc gcgcccaggc
   133261 ggcagaagca agggccaaaa cagctgaatt acaggttcag aaactggctg aaacacaaca
   133321 acaaaatcag ctaacaactc aagaagtagc acagagaaca gttcagctcg aacagaaatc
   133381 cgcagaaaac agtggttttg agtttcatgg ctatgcccgt tccgggttac tgatgaatga
   133441 tgccgcttcc agtagcaaaa gtgggccgta tctgactccc gcaggtgaaa ctggtggagc
   133501 tgttggccgt ctgggaaatg aagccgatac ctatgtcgag ttaaatgtag aacataaaca
   133561 aacactggat aacggtgcga ccacacgctt taaagcaatg ttggctgacg gacaaagaga
   133621 ttacaacgac tggactggcg gctccagtaa cctgaatatc cgacaggctt ttgccgaact
   133681 gggcgcatta ccaagtttta ccggagcatt caaagacagt actgtctggg ctggtaaacg
   133741 ctttgatcgc gacaattttg atattcactg gttagactcc gatgtcgtat ttttagcggg
   133801 aacgggcggc ggtatctatg acgtaaaatg gaacgagaca ttccgcagta acttttctct
   133861 ctacggacgt aatttcggcg atcttgatga tatcgacaat aacgttcaga actacatcct
   133921 caccatgaat cattatgcag gccccttcca gttgatggtt agcggattac gggcaaaaga
   133981 taatgatgat cgaaaagatg ccaatggtga tctcattcaa actgatgctg caaatactgg
   134041 cgtacatgcg ttagttggtc tgcacaatga cactttctat ggcctgcgtg aagggacggc
   134101 aaaaacagca ctgctatatg gccatggcct gggtgcggaa gtcaaaggga ttggctccga
   134161 tggcgctctg ctgtctgagg cgaatacctg gcgcttcgca tcttacggca caacacctct
   134221 gggaagcggt tggtatgttg cgccagcaat tctcgcacaa agcagtaaag atcgttacgt
   134281 caaaggcgat agctacgaat gggtgacctt caatacacgt ctgatcaaag aggtaacaca
   134341 gaattttgct ctggcctttg agggtagcta tcaatatatg gatctgaagc caaaggggta
   134401 tcaaaaccac aacgccgtaa acggcagctt ctataaactc acctttgctc caactctaaa
   134461 agctaacgat atcaataatt tctttagccg tccggagctt cgcctgtttg ccacctggat
   134521 ggactggagc agcaaacttg atgattttgc cagcaatgat gctttcggca gcagtggttt
   134581 caatactggc ggagagtgga attttggtgt ccaaatggaa acctggtttt aataccagac
   134641 agcctcacgg atgtgaggct tttactgaaa taacaatgaa ttagagggtt atatggattt
   134701 cgataaaatc gcccaatcgt tgcttccttt attaggtggt aaggagaaca tcgccagtgc
   134761 agcacattgc gccactcgcc tacggctggt actggttgac gacacacttg ccgatcaaca
   134821 tgccattggc cagattgatg gagtgaaagg ttgttttcgt aattcagggc aaatgcaaat
   134881 catctttggc accggcgtgg ttaataaagt ctatgctgcc tttattcagg ttgcaggtat
   134941 tagcgaatcc agtaaagcag ataccgctcg actcgccgct caaaaactca atccttttca
   135001 gcgaatagca cggctacttt ctaatatttt tgtccccatc attccagcca ttgttgcttc
   135061 tggtttatta atggggcttc tgggaatggt gaaaacatat ggctgggtga atgccgataa
   135121 tgcgatttat atcctgctgg atatgtgcag ttcagccgca tttattattc tccccatcct
   135181 tattggcttt actgctgctc gtgaatttgg tggaaatcct tatcttggcg cgacattagg
   135241 agggattctg actcacccgg cactcacaaa tgcctggggc gttgctgcgg gatttcagac
   135301 aatgaacttc ttcggttttg aaatcgccat gattggctat cagggaacgg ttttccccgt
   135361 gcttctggca gtatggttta tgagcatagt ggaaaaacag ttacgcaggt ttatccctga
   135421 tgctctggat ctcattctga cgccatttct gactgtcgtc atttctggct ttatcgctct
   135481 tttgattatt ggtccggcag gacgagcgtt aggtgacggt atctctttcg ttctcagcac
   135541 gctgattgca cacgcaggct ggttagcagg gttgttattc ggcgggctat attcagcgat
   135601 tgttattacg ggtattcatc atagcttcca cgcaattgaa gcaggacttt taggtaaccc
   135661 tgcaatcggt gttaatttcc tgctgcctat ttgggcaatg gcaaacgttg cgcaaggcgg
   135721 tgcatgtctg gcggtatggt ttaaaaccaa agatacaaaa attaaagcaa tcaccctacc
   135781 ctcggccttt tccgcaatgt tagggattac tgaagccgct atttttggta tcaaccttcg
   135841 ttttgttaaa ccttttattg cggccttaat tggtggcgct gccggcggtg cctgggttgt
   135901 ctctgttcac gtttatatga ctgccgttgg tctgaccgca atacccggca tggcaatcgt
   135961 tcagccaaca tcgttggtta attatattat tggaatggtg attgctttcg ctgtcgcttt
   136021 tagcctctct ttattactca aatacaaaac ggacgaggag taatgtcgat gccttcacaa
   136081 atgcccgcga ttttacaggc agtgatgaaa ggtcagtcca aagcactggc agatgcccac
   136141 tatccttgtt ggcatctcgc tccagtcacc ggactaatga acgatccaaa tggcttttgt
   136201 tggtctggag gccgctatca tctgttttat caatggaatc cactggcttg tgatcataag
   136261 tacaaatgtt gggggcactg gagttcgacg gatttattgc actggcagca tgaaccatta
   136321 gcgctaatgc ccgataaaga gtacgaccgt aatggttgtt actcaggaag cgcggttaat
   136381 aatcagggcg ttctcacact ttgctatacc ggtaatgtta agtttgatga tggcagcaga
   136441 acagcatggc aatgtctggc caccgaaaat aaccagggcg ggtttgataa actaggccct
   136501 gtcataccgt tacctgatgg ttacaccgga catgttcgtg atccaaaagt ctggaagcac
   136561 aacagccaat ggtacatggt gcttggcgcg caagataaag agaaacgggg gaaagtactg
   136621 ctgtattcct ctgtcgatct ctatacctgg tcttttcatg gagaaattgc tggtaatggt
   136681 ctgaatgaaa tagataacgc aggatacatg tgggaatgtc ctgatctttt cgcccttgat
   136741 ggtgaataca ttctcctctg ctgcccccag ggaatggcgc gcgaacatga gcgctatctg
   136801 aatacttatc cctgcgcctg gctacatgga cagtttgatt acgagacagg caagtttacg
   136861 catggcgctt tctcagagct ggatgcggga tttgaattct atgcaccaca gacgatggaa
   136921 gccccggacg ggcgacgatt gctggtcggc tggatggggg ttcctgatgg cgaagagatg
   136981 ttgcaaccaa ccagaaagca tcattggcag catcaaatga cctgttttcg cgaactctca
   137041 ttccagaagg gaaaattgtt tcagatgcca atcagggaac tcgcgcaact gcgtgaagct
   137101 gaacacttct ggcaaggaaa agcggatcat gcgccgcatg tcgaaattga acgcctggaa
   137161 atggacatca ttccgtcggg tgagctgtat ctgaattttg gcaatgcgct ggcactgcat
   137221 cttaatgacg atggtattca actacagagg agaagccttg cagggcaaga gaaactaact
   137281 cgttactggc gaggaagcgt aacgtcactg aagattctct gtgacagttc cagcgtagag
   137341 atattcatca ataatggtga aggtgtaatg agtaatcgtt attttcccca tcatccagct
   137401 tcgctgatat tacagggtga gtctgacgtc acgttacgct actggtcgct acgcgcctgc
   137461 atggtagaat gagggttttg aattacggat cctcgtcgtg agaaaaacca aacgcgttac
   137521 tattaaagac attgctgaac tggcgggagt gtcgaaagca accgccagtc tggttctcaa
   137581 tggtcgtggc aaagagttac gtgttgcgca ggaaacgcgt gagcgtgtgc tgagtattgc
   137641 ccaacagcag cattatcagc ccagcattca tgcccgctca ttacgggaca accgcagtca
   137701 taccattggt ctcgtcgttc ctgaaatcac taactacgga tttgcagtat tttcccatga
   137761 actggaaaca ttgtgtcggg aagcgggcgt ccaactcctc atatcctgta ctgatgaaaa
   137821 tccttcacag gaaacaatgg tggtgaacaa tatgattgcc cgccaggttg atgggttaat
   137881 cgtcgcatcc agtatgctgc atgataatga ctatcaaaaa cttagcgagc aattacctgt
   137941 tgtgttgttc gatcgccaca tgaacggcag cacattgcca ttggtcatta ctgactctgt
   138001 ttctcccacc gccgctctgg tggcagatat tgcacggagt cacccggatg aattctattt
   138061 tctgggggga caaccccgtt tgtcaccgac tcgtgatcga ctggaaggat ttacacaagg
   138121 cttgcagcaa gccggagtaa cgctacaacc tgaatggatt attcacggta attatcatcc
   138181 gagctcaggc tatgaaatgt ttgccgcgct atgcgctcgt ttaggacgtc cccctaaagc
   138241 cttattcact gccgcttgtg gattactgga aggcgttctg cgctatatga gccaatataa
   138301 tttactcgac agtaaaatcc acctggcgag ttttgatgat cattacttgt atgattcact
   138361 ttcggtaaga atcgacacaa tacaacagga taatcgccaa cttgcttttc actgctttga
   138421 acttatttcg caactgattg aaggtgaaac gccatcccca ttacagcgtt atcttcctgc
   138481 cagtctacaa aaacgctacc gataatcccg tcactatctt gcatcgcccc tgtaaaacgg
   138541 ggcgattatt ttcatcctga acgttaaata tcaatgatgc ataatcaaat caggcaatat
   138601 ttaaatattt atgcgtttgc atcgacaaac gccagttgcg cgcaatgcag gtatcgatac
   138661 ataaacgcgt agcatcttcc ttctggctaa ttggctgcag tgcaatgact cgcggtttat
   138721 catcggtcag cgtcgcaagc aattcatcca gtgcttcgat atcacgtacg cgtcccactg
   138781 ggtgtttgat ttcgttggct cgctccagtg cctgtgacaa cacttcatag ccaccgcgca
   138841 tattcagctt tggcgacacg gtgacccagg tattcggtgt acagcgtact tcatgagtac
   138901 cactggtttc tatctggcag ctaaaaccgt tcttttcgag caggtcagtc agcggcagca
   138961 aatcatgaat gcaaggctca ccacccgtaa tcaccacgtg acgcgcggtg tatccctgac
   139021 ggccaatgac agccagcaaa tcttcactgc tcgccgcccc ccacttatca ctctctttgg
   139081 tcttcgccag aatgctgaaa agggagactt cccgatcctc aagcttttcc caggtgtgtt
   139141 tggtgtcgca ccaggcacag ccaaccggac atccctgtaa acgaataaaa atggcgggga
   139201 cgccggtaaa gtaaccctca ccttgcaggg tctggaacat ctcgttaatc gggtactgca
   139261 tagcattctc tgtgaagtgg ataattgtta attattgcag atcctgccac aacaatcatg
   139321 tcttattaac attctgttac cggcaggttt aaagaaaaat gcgaaacata tcgttaataa
   139381 taaaagggag tgacgtatta tgtcagaaag aaataaagta aagggattta atcatgtcaa
   139441 aaacattcac caaaattata tttatctttt ctgtattcat ttttaattat aacgaacctc
   139501 aaattaccga taccgccgtc aatttattta tccagcttta ataggacatt tataatgcgc
   139561 tatttcatac taatattcac actcgtgtgt tcctttgttg cagcccaacc aactattgtc
   139621 ccacaattac agcaacaagt tacggatctt acgagtagct taaactcaca agaaaagaaa
   139681 gaactgacgc gcaagctaga atctattttc aataataccc aagtacaaat tgctgtatta
   139741 attattccca caaccaaaga cgagacaatt gaacaatatg ctgcaagggt ttttgacaat
   139801 tggcgtttag gagatgccaa acgcaatgat gggatactga tcattgttgc ctggtcggat
   139861 cgcactgtcc gcatccaggt aggttatgga ctggaagaaa aggtaaccga tgctctggct
   139921 ggagatatca tccgtagcaa catgataccc gcatttaaac aacaacaatt agctaaagga
   139981 ttagagttag ctataatcgc tttgaataac cgactcactt cacaacacca atattcggtt
   140041 aatccttcag aaagtgaatc agcatcttcc agcgatcatt actactttgc tattttttgg
   140101 gtatttgcag tgatgttctt ccctttctgg ttttttcatc aaggcagtaa tttttgtcgc
   140161 gcatgtaaaa gcagtgtctg tatttcagca atctatcttt tagatttatt cctgttctcc
   140221 gataaaactt tttccattgc tgtatttttc ttctttttta ctttcaccac cattatggtc
   140281 tttacctgtt tatgtgtact tcagaaaaaa gcatctggta gaagttatca ttcagacaac
   140341 agcggttccg gtggcggctc aagtggcggc ggatttagcg gcgggggcgg ttcttctggc
   140401 ggtggcggcg cgtccggtcg ttggtaactc aaccataaaa aacgccagcc cgaaggctgg
   140461 catttttaaa tcagataaag tcagacttat gcctggcctt tgatctcttt acgaccgttg
   140521 tacggtgctt tttcgcccag agcttcttcg atacgaatca gctggttgta tttagcaaca
   140581 cggtcagaac ggctcataga acccgttttg atctggcctg cagcagtacc aacagccagg
   140641 tcagcgatgg tagcgtcttc agtttcgcca gaacggtgag agataactgc agtgtagcca
   140701 gcgtctttcg ccatcttgat tgcagccaga gtttcggtca gagaaccgat ctggttgaat
   140761 ttgatcagga tggagttagc gatacctttt tcgatacctt ctttcaggat cttggtgttg
   140821 gttacgaaca ggtcgtcacc aaccagctgg attttgtcgc ccagaacttt ggtttggtat
   140881 gcgaaaccgt cccagtcaga ttcgtccaga ccgtcttcga tggaaacgat cggatactgt
   140941 ttggtcagtt cttccaggaa gtgagtgaat tcttcagagg tgaatgcttt gttgccttcg
   141001 ccagccagaa cgtatttacc gtctttgtag aattcagaag ctgcgcagtc catcgccaga
   141061 gtgatgtctt tgcccagttc ataaccagca gctttaacag cttcagcgat aacagccaga
   141121 gcttcagcgt tggaacccag gttcggcgca tagccacctt cgtcaccaac agcagtgttc
   141181 atgcctttcg ctttcagaac ttttgccagg tgatggaaaa cttcagaacc catgcggatg
   141241 gcttctttca cagttttcgc gccaaccggc tgaatcatga attcctggat atcaacgttg
   141301 ttgtcagcgt gctcaccacc gttgatgatg ttcatcatcg gaaccggcat agagtatttg
   141361 cccggagtgc cgttcagttc agcgatgtgc tcgtacagcg gcataccttt agcagctgca
   141421 gcagctttgg cgttagccag agatacagcc aggattgcgt ttgcgccgaa tttggatttg
   141481 ttttcagtgc cgtccaggtc gatcatgatc ttgtcaatgc cagcctgatc tttagcatct
   141541 ttgccaatca gcgcctgagc gatcgggccg ttaaccgcag caacagcttt ggttacgcct
   141601 ttgcccagga aacgggattt gtcgccatcg cgcagttcca gagcttcacg ggaaccagta
   141661 gaagcacctg acggagcagc tgccataccg acgaaaccac cctccagatg tacttcggct
   141721 tcaacagtcg ggttaccacg ggagtcgatg atttcacgac cgatgatttt tacgattttg
   141781 gacattaggt tttcctcaag tcactagtta aactgaaact ccagacaaac aacgcgtacc
   141841 cagggtacgc gttgccgttc taactttttt acttacttcg cctgacgttt ctggaactcg
   141901 ctggcggctt ttacaaagcc agcaaacagc gggtgaccat cacgtggagt agaagtaaac
   141961 tccggatgga actggcaagc cacgaaccac ggatgattcg gaacttcgat gatctcgacc
   142021 aactgatcat ccccggaacg gcccgcaacg cgcagacctg catcttcaat ctgtttcaac
   142081 agcatgttgt tgacttcgta acggtgacga tgacgctcaa caattgtcgg cgcattgtac
   142141 agctggcgaa ccaggctatc gtcaaccaac tggcactgct gtgcgccgag acgcatggta
   142201 ccgccgagat cgctcttctc gctacgaact tcaacgttgc cgttttcatc gcgccactcg
   142261 gtaatcagcg ccacaaccgg gtacttacag tctggcacaa attccgtaga gttggcgttc
   142321 tccatgttgg caacatggcg agcgtaatca attaacgcca cctgcatacc caggcaaatg
   142381 cccagataag gaatattgtt ctcacgcgca aaacgcgcgg tcgtaatcat gccttctacg
   142441 ccacgatagc cgaaaccgcc aggtacgagg attgcgtcca gacctttgag gatttcaacg
   142501 ccgcgcgttt caacatcttg tgaatcgatc agtttgatgt tgacgctgac acgattcttc
   142561 agcccaccgt gtttcagtgc ttcgatcacg gatttgtatg catccggcag ctcaatgtat
   142621 ttgccgacca taccaatggt gacttcactt accggattcg cttcttcgaa gataacctgt
   142681 tcccattcgg acagattcgc ttccgggcag tttaagctga atcgtttaca aatataatcg
   142741 tccagcccct gagatttcaa caggcccgga attttataga tggaatcgac gtctttcaga
   142801 gaaataaccg ctttttccgg aacattacag aacaatgcaa tcttcgcacg ttcgttcgct
   142861 ggaacggcgc gatctgaacg acaaatcagg atatcaggct ggataccgat tgaaagcagc
   142921 tcttttacag agtgctgagt cggtttggtt ttgacttcac ctgacgctgc catgtacggc
   142981 accagcgtca ggtgcataaa cagggtgtgc tcacggccaa tttcaacagc catctggcga
   143041 atcgcttcga ggaacggcag ggattcgata tcaccgacag taccgccgat ttcgaccagt
   143101 actacgtcat gaccttcgcc gccttccagc acgcgctctt tgatagcgtt agtgatgtgc
   143161 ggaataacct gtacggttgc gccgagatag tcaccgcggc gttctttacg cagaacgtca
   143221 gagtagatac gacccgtggt gaagttgttg cggcggctca ttttggtacg aatgaaacgc
   143281 tcgtagtgcc ccaggtccag gtcggtttca gcgccgtctt cagtaacgaa cacttccccg
   143341 tgttggattg ggctcatagt accgggatcg acgttgatgt acggatccag tttcatgatg
   143401 gtcacattga ggccacgggc ttcaagaatg gctgcgaggg aggctgcggc aatgccttta
   143461 cccagagagg atacgacccc gccggtcaca aaaatatagt tcgttgtcat gctgaacctg
   143521 agaagttagg ttgaaaagac gatggaataa ccaggacggg aaagcagtat acccgaacat
   143581 gacctgtgcc acaaactttc attatccctc ctcttcgcca gcgcactatt gaaatcagga
   143641 gtgagaaaat agcccctttg gggtaaatgt ttttgacgca aatcaagcgc ttgtcattta
   143701 aaaaatgaca caaatcgcgc ttgaccacgt aattccctta gagatcaatt tcctgccgtt
   143761 ttacctgttg ccagacttct tccattgttt cgaggtcaac acctgtcatt tccagtccac
   143821 gcgcggcaac aatacgctcc acttcgcgaa aacgacgctc gaatttttcg ttcgcttttt
   143881 gcaatgcgat ttccgctttt gtccctaaat gacgagccag attgaccgtg gcaaacagca
   143941 ggtcacccat ttcctcctcc agtttagcct ggtcgacaac agcctgccgc gcctcgtaca
   144001 tcacctcgtc gatctcttcg tagactttat cgactaccgg accaagcgtc gtccagtcga
   144061 aaccaacgtt ggcgcaacgt ttctggattt tttgcgcacg cattaaagcc ggtaaactac
   144121 gaggaatatc gtccagcgcc gaatgctgcg ctttctgcgc gcgctcttcg gttttgattt
   144181 gctcccaacg ggcaagcact tcactactat tttcggcaga actgtcagca aaaacatgcg
   144241 gatggcgacg ctctaattta tcgctaatag cagcgcaaat atcattaaag tcaaagcgcc
   144301 cttcttcctg agctatttgt gcgtaaaaca ccacctggaa cagcagatcg cccagttcac
   144361 cgcgcagatc gtcaaaatct tcacgggcga tggcgtccag cacctcgtag gtttcttcaa
   144421 gggtgtaagg cgcaatggtg gcaaatgtct gctctttatc ccacgggcag ccgttttccg
   144481 ggtcgcgcag gcgctgcatg atggtgagca aacggtcgat ttgattcatt gaattatcct
   144541 gaaaattgcg ggtccgtcag gtgtaatacc ttcgagtaaa agatatcgct ggatacggct
   144601 gacgccatat ccagctatgt aagattaact cccgtgcaac cgacgcgcgt cgataacatc
   144661 cggtacctgg ttgagtttac ccagcacgcg acccagcact tgcaggttgt aaatctcaat
   144721 ggtcatgtcg atggtcgcca gttgctgttt ggtgtcgcta cggctggcaa cgccaagtac
   144781 gttcaccttc tcgttggcga gaatggtggt gatatcacgt aacaacccac tacgatcatt
   144841 agccaccacg cggaccacca gcgaatatcc ggcggagtag ctctcgcccc ataccgcgtc
   144901 aacaatgcgt tctggcgcat gggagcgcag ttccgccaat tgttcgcaat cggcgcggtg
   144961 tactgaaata ccgcgcccct gggtaatgaa gccgacaatc tcatctccag gaatcggctg
   145021 gcagcagcgc gcgatgtggt gcatcaggtt accgacccct tctaccacca cacgaccgtt
   145081 atctttactg cggttttgcg gcgtgtagct tttttgctga agctgtttca gcgcggcggc
   145141 gtcctgctct tcggcactcg gcttattaaa ttgcgattgc aggaagttca ccatctgatt
   145201 gagacggata tccccgccac caatcgccgc cagcaactcg tcgacatcat tgaagttgta
   145261 acgcggcagc agatgttttt ctgcttcttt caggctgatc cccagatgtt ccagctcgtc
   145321 gtcaaggatt tgccgcccag ccagaatgtt tttgtcacgg tcctgtttac ggaaccaggc
   145381 gtgaattttc gaacgcccac ggctggttgt gacgtaaccg aggtttgggt ttaaccagtc
   145441 acggctgggg ttcggctgtt tctgggtgat aatttcaatc tggtcgccca tctgcagctg
   145501 gtaggtgaac ggcacaatgc gcccgccaat ttttgccccg atgcagcggt gtccgacatc
   145561 actgtggatg tggtaagcga agtccagcgg cgttgatccc gcaggcaaat caacgacatc
   145621 acctttcggc gtaaagacgt acactcggtc gtcaaagacc tgactacgta cttcgtcgag
   145681 catttcgccg gaatcagcca tctcttcctg ccacgcaatc agtttacgca gccaggcaat
   145741 ccggtcttca tgtcccgaac gtgcgccgcc agcagccgcg ccctctttat atttccagtg
   145801 cgcagcaaca cccaactctg catcttcatg catctgtttg gtgcggattt ggatctcaac
   145861 ggttttgcca cccggcccca gaaccacggt atgaatagac tgataaccgt ttggtttcgg
   145921 gttagcgacg taatcgtcaa actcatccgg caggtggcga tagtgagtgt gcactatccc
   145981 cagtgcggca taacaatcct gtaaacgctc ggcgacaata cgtaccgcac gcacatcaaa
   146041 cagctcatcg aaggcgaggt tctttttctg cattttgcgc cagatgctgt agatgtgttt
   146101 cggacggcca tacacttcgg ctttaacgcc ttcagctttc atctcagcgc gcagatggcc
   146161 gacaaactct tcgatatagt gttcgcggtc gagacggcgt tcatgcaaca gttttgcgat
   146221 gcgtttgtat tcggtcgggt ggagataacg gaagcagtaa tcttccagct cccatttcag
   146281 ttgcccaatc ccaagacggt tcgccaacgg cgggtagata ttggtgcact cttttgccgc
   146341 cagtacacgt tcatcttccg gcgcatcttt tacttcgcgc agatgagcaa tacgctccgc
   146401 cagtttgatg actacgcagc gaaaatcatc gaccatcgcc aataacatcc ggcgaacgtt
   146461 atcgacctgt tcggaggaaa cagaatcagt gtgcgtcgct ttcagctggc ggatcgccgc
   146521 catatcacgc acgccgtgaa taaggttaac gaccgactta ccgacgctct cgcgcagcac
   146581 atcttcgctg actacgttgg catcagccag agggaatagc agcgccgccc gcagcgtgtc
   146641 aatgtccata cttaatgtcg agaggatctc caccatctca acaccacgcc acaataacag
   146701 actggcatcc ggatgcccct gcgtctgttg cagacaatac gcccaggttt cggctaagca
   146761 ctcacacgac ttctggctgg taatacccag acttgcgatc catttttccg gatcaaattc
   146821 accagcctta ttgatatgtg cacttcttac cgcaaccatc gtcctctcct ttagggacca
   146881 gacctgccga aatcggcaaa tcgtaactat ttaacgcgcg agaaaagtac catcgattcc
   146941 agatgtcccg tgtgtgggaa catatccagc atcgccagtc gcgcaatggt atatcctgct
   147001 tttaataacg cttcgctatc ccgagccagc gttgcagggt tacaggatac ataaactata
   147061 cgaataggtt ccagttttat aatttgctgc ataacacctg cggcacctgc tcgcgccggg
   147121 tccaacaaca ctttatcgaa gccgtttttc gcccacggct gctttgtgac atcttcttca
   147181 agattttcgt gataaaacgt cacattctgt aagccattaa gacgcgcatt ctgctggcct
   147241 ttttccacca gcgccggaac accttctaca ccgaccacac tggcagcttg tgtcgccaat
   147301 ggcagtgtaa agttgcccat accgcagaac agatccagta cgcgatcttc aggttccaca
   147361 tccagccatt ccaacgcacg cgctaccatt ttttggttca cacccgcatt gacctgaata
   147421 aaatcgcgcg ggctaaaagt taagcgcaac ccatttgagt cataccaggg catctcacca
   147481 gagacggttt cgagtatctc actatcgggg gcgagataca gatccaggcc ttcagaatgc
   147541 gaaaagcatt ccagtttttc gcgatctgcc gaacttagcg gtgcggtatg gcgcaaaatc
   147601 attagcgtgc cgctggttgc ctgtaccagt tcaacatgac caagatggcg catagcttgt
   147661 aagctgccca ggcatgccct gactttgggc agcaatgctt ctagttgggg cactaaaatg
   147721 gggcattgtt taacgtcgac aatgtcactg gagcccgctt tgcgaaaccc catctgaagt
   147781 tgctgtgttt tcggtaagta gttcagactt aaacgcgcgc gacggcgata gccccaagga
   147841 acatcggcga tcacttcaga gacttcgtgt ttcattaatc gggcgagtgc cgcacttttg
   147901 cttcgctgct gtaaatccac gctggcgtgt tgttgctgac agccgccgca tacgccaaaa
   147961 tgaggacagc gtggcgtttc gcgttccggg ctatcgctta accggcgtac gactttagcg
   148021 cgggcatact gttttttatc ttcagtaaca gtaacttccg cgttttcctg cggcaataat
   148081 ccggggataa ataatgtttt gccgttatgt cgcgccacac cctgaccaaa agagtcgagg
   148141 tcgttgactg aaacggttat gatctgacgc gtcgtcgtgc gtcgttttgc agagtagaat
   148201 tgcgccattg gcgagacttt ctcaatttaa cagtgtgacc ttaattgtcc cataacggaa
   148261 ctccatgacc aactacagcc tgcgcgcacg catgatgatt ctgatcctgg caccgaccgt
   148321 ccttattggt ttattgctga gtatcttttt cgtcgtgcat cgctataacg acttgcagcg
   148381 tcaactggaa gatgccggtg ccagcattat tgagccgctt gcagtttcta ctgaatatgg
   148441 catgagtctg caaaatcgcg aatctatcgg tcagttaata agcgtactgc atcgtcgcca
   148501 ttctgatatt gttcgcgcga tttcggttta tgatgaaaat aaccgactct ttgtcacctc
   148561 caattttcat cttgatccct catcaatgca gctcggcagc aacgtgccgt ttcctcgcca
   148621 gctcactgtc actcgtgacg gcgatattat gatcctccgc acgccgatta tttctgagag
   148681 ttactccccc gacgaatcgc ccagtagcga tgccaaaaat agtcaaaata tgttgggata
   148741 tattgcgctt gagctggatc ttaaatcggt tcgcttgcag caatataaag agatctttat
   148801 ttccagcgtg atgatgctgt tttgtatcgg tattgcgctt atttttggct ggcgcttaat
   148861 gcgcgatgta accggtccga ttcgcaacat ggtgaatacc gtcgaccgca tccgtcgcgg
   148921 gcaactcgac agccgggtgg aaggatttat gctcggcgag ctggatatgc tgaaaaacgg
   148981 tatcaactcg atggcaatgt cgctggcggc ttatcacgaa gagatgcaac acaatatcga
   149041 ccaggcgacg tccgatctgc gtgagacgct ggagcaaatg gagattcaga acgttgagtt
   149101 ggatctggcg aaaaagcgcg cccaggaagc ggcgcgtatt aaatccgagt ttctggcaaa
   149161 tatgtcacac gagctgcgta caccactgaa tggtgttatt ggctttaccc gcctgacgct
   149221 gaaaacagaa ttaacaccaa cgcagcgcga tcacctgaat acgattgaac gttcggcaaa
   149281 taatttgctg gcaattatta atgatgttct cgacttctcg aaactggaag ccggtaagct
   149341 gattctggaa agtattccgt tcccactgcg cagcacgctg gatgaagtcg ttacccttct
   149401 ggcacactct tcccacgata aagggctgga attgacgctc aatattaaga gcgacgtccc
   149461 cgataacgtg attggcgacc cgctacgttt acagcaaatc atcactaacc tggtggggaa
   149521 cgcgattaaa ttcaccgaga atggcaacat cgatattctg gtggaaaaac gtgcgctgag
   149581 taataccaaa gtgcaaattg aagtgcagat tcgggatacc ggcattggta ttcctgaacg
   149641 cgatcaatcg cgcttattcc aggccttcag acaggctgat gccagtattt cccgccgtca
   149701 tggtggcacc gggctggggc tggtgattac acaaaaactg gttaatgaaa tgggcggtga
   149761 tatttcgttc catagcctgc cgaatcgtgg ttcaactttc tggttccaca ttaatctcga
   149821 tctgaacccg aacattatta tcgaagggcc atccacccag tgcctcgctg gtaagcgcct
   149881 ggcctatgtc gaaccaaact ccgcagcagc acaatgcacg ctggatattt taagtgaaac
   149941 gccgctggaa gtggtttata gcccaacgtt ctccgcgctg cctcccgcgc attacgacat
   150001 gatgttgtta ggcatcgcgg tgaccttccg cgagccgcta acaatgcaac atgagcgatt
   150061 agcgaaagcg gtatcgatga ccgatttcct gatgctggca cttccttgcc atgcacaagt
   150121 caatgctgaa aaacttaagc aagatggtat cggcgcgtgt ctgctgaaac cattaacacc
   150181 tacgcgcctg ttgcctgccc tgacggaatt ttatcatcac aaacaaaaca cgcttttgcc
   150241 tgtaaccgat gaaagtaagc tggcaatgac agtcatggcg gttgatgaca accccgctaa
   150301 cctgaaactt atcggcgcat tgctggaaga tatggtgcaa catgtggaac tttgcgatag
   150361 cgggcatcag gcagttgaac gggcgaaaca gatgccgttc gatttaatct taatggatat
   150421 tcaaatgccg gacatggacg gcattcgggc atgtgagctc atccaccagc tcccgcatca
   150481 gcagcaaacg ccggttatcg cggtaacggc gcatgcgatg gccgggcaaa aagagaaact
   150541 gcttggcgcg gggatgagtg attatctcgc caaaccgatc gaagaagagc gattgcataa
   150601 tttgctgttg cgctacaagc ctggcagcgg tatttcctct cgcgtcgtga cgcccgaagt
   150661 caacgaaatt gtggtcaacc cgaatgcgac cctcgactgg caactggcac tacgccaggc
   150721 agcaggaaaa accgatttag cgcgcgatat gctgcaaatg ttactcgatt tcctgcctga
   150781 agttcgcaac aaagttgagg aacagctggt tggagaaaac ccggaaggcc tggttgattt
   150841 gattcataaa ctgcatggca gttgcggcta tagcggtgta ccgcgtatga agaatctctg
   150901 ccaactgatc gaacaacagc tacgtagcgg tactaaagaa gaagatttgg agccggagct
   150961 gctggaactg ttggacgaga tggataatgt agcgcgcgaa gccagcaaaa ttctcgggta
   151021 atggacgtct tgtcgagtag caaccggatt tttatgacgc tggtttcaga ttggtgacaa
   151081 gtgcctgtgt ttatgccgga tgcggcgtta acgccttatc cggcctgcaa aaccaattaa
   151141 attcaatgaa ttaaaaaatg atgtagccct gatacgtagc gcaacaggca attttgcgtt
   151201 tggcatcagt ctcaaaccgg ctccagatag agccggtttt ggttttctgt cttaacgcac
   151261 catgcacgga cgcttgttat cgaacgtcca gccggggatc aggtactgca ttcccatcgc
   151321 atcgtcacgc gcgccaagcc cgtgtttctg atacagctcg tgcgctttca tcacttgatc
   151381 catatcgatt tctacaccca gccccggttt ttctggcacc tgaaccagac cgcctttgat
   151441 ctctaacggt tctttggtca ggcgctgatt accttcctgc cagatccagt gcgtatcaat
   151501 cgcggtgatt ttacccggtg cggcagcggc aacatgggta aacatcgcca gggaaatatc
   151561 gaagtggttg ttggagtgtg aaccccaggt caggccaaat tcatgacaca tttgcgccac
   151621 acgtaccgaa ccttgcatcg tccagaaatg cggatccgca agcgggatat caacggattg
   151681 caacgagagc gtatggccca tctgccgcca gtcggtggcg atcatattgg ttgcggtcgg
   151741 caggccagtt gcgcgacgga actctgccat cacttcacgc ccggagaaac cttgctccgc
   151801 accacacgga tcttctgcat aagccagcga acctttcagg tatgtaccga ttttaatcgc
   151861 ttcgttcagc gaccaggcac cgttaggatc gagcgtaata cgcgcctgcg ggaaacgttg
   151921 cgccagtgcc acaatagatt ctgcttcttc ttccccggcc agtacaccgc ccttcagttt
   151981 gaaatcgttg aagccatatt tttcatatgc cgcttccgcc aggcgcacca ccgcatccgg
   152041 cgtcatcgct tcttcgtgac gcaggcgata ccagtcacat tgatcatccg gctggctttg
   152101 atacggcagc ggtgtggctt tgcgattacc gacgaagaac agataaccga gcatttcgac
   152161 ttcgctacgc tgttggccat cgcccagcag cgatgccacg tttaccccca gatgctgccc
   152221 caacagatcc agcattgccg cttctatccc ggtaactaca tgaatagtgg tacgcaaatc
   152281 aaatgtctgc aaaccgcgcc caccggcatc acgatcggca aacgtattac gcaccagcgt
   152341 cagaacgttt ttgtattcac ccagcgtttt acccaccacc agcggaatcg catcttccag
   152401 cgttttacgg attttctcgc cgccgggaat ttcccctacg ccagtgtgac cggaattatc
   152461 tttgataatc acaatattac gcgtgaagaa cggtgcatgt gcaccactca gattcatcag
   152521 catactgtca tgacccgcca ccgggatgac ctgcatttca gtaacaacag gcgtcgtaaa
   152581 ttgagaactc atatttatgt cctttttcag aatcaatgac ggccgaaaac ggggcgttta
   152641 cggtcaaagg tccagccggg gatcaggtac tgcatcgggc ctgcgtcgtt acgcgcaccg
   152701 ccaggcagac gtttataggc ctcatgtgcc ttttgtacct gttcccagtc cagttccacg
   152761 cccagaccgg gcgcatcagg aacggcaatt tttccgtttt taatctccag cggatttttg
   152821 gtcagacgac aatcgccctc ctgccaaatc cagtgggtat cgatagcggt aggattaccc
   152881 ggtgccgccg cgcccacatg ggtaaacatc gccagagaga tatcaaagtg gttattagaa
   152941 tggcagcccc aggtcagccc ccagtcgtcg caaagttgcg ccacgcggac tgcaccggaa
   153001 agcgtccaga agtgcggatc ggcaagtgga atatctaccg cattgagcat caccgcatga
   153061 cccatttcgc gccagttggt ggcaatcatg ttggtcgcga cgggcaagcc ggtcgcccgt
   153121 cgaaactccg ccatcacttc acgaccggag aaaccctgct cagcgccgca cgggtcttcc
   153181 gcataggtaa gaacatcatt cagccctttg cacagagaaa tggcttcatc aagcagccag
   153241 gcaccattgg gatcaacggt aatccgcgca tccgggaagc gtttcttcaa tgcacgaaca
   153301 gtgtcgattt cttgctcgcc aggtaacacg ccacccttaa gtttgaaatc tttaaagcca
   153361 tagcgatcct gtgaggcttc cgccagacgc acaacggctt cgctgttcat cgctttctga
   153421 tgccgcaact gataccactc atggttgccc ggcgtatttt ccagataagg aagatcggtt
   153481 ttggtccgat caccgatata aaacagataa ccgagaacgg taatagcatc acgttgcttg
   153541 cctggcccta acagttcgca gaccggaaca ttcagcgcct gacctaacag gtcaagcaag
   153601 gcggcttcca gcgccgctac ggcattaacg cgcaattcaa aagtccaggc acctttgccg
   153661 aaggtatcaa aatcggctgc ctgattacct ttatgcacct gctgaaccac tttattcagg
   153721 cgcgcaactt cctggcccag caccatcgga atagccccga ccagtgtttg ataaatcacc
   153781 tctccgcccg gcgcttcacc aatgccggta tgcccggcat tatcggtgag taccacaata
   153841 ttgcgggtga aatatgcgtt atgtgcacca ccaatattaa gcaacatgct gtcatgtccg
   153901 gcgaccggaa tgactttcat atcagtaata acaggactgg attgtgtcgt catcttattg
   153961 ccccgcgaca ggtttcagct caatacgctt gatatcgccc accagcacca ggtagctgag
   154021 taccgcgatt aaggcatgaa caccaacata aatcagcgcc ccattaaagg agccagtcgt
   154081 gccaacgata taaccaattg cgattggcgt gacgatgcca gaaatgttac caaacatgtt
   154141 gaacaggcca ccggaaagac cgctgatctc ttttggcgca gtatcagcca ttacagccca
   154201 acccagcgca ccgatcccct taccgaagaa ggccagcgcc ataaagccga tgatcatcca
   154261 ctcaacgttg acgtagttgc agaacaccat caccatcgac aacaacatgc ccatcacgat
   154321 cggtgtttta cgcgcaatgt tcagtgaacc cgtgcgacgc atcagccagt cggaaataat
   154381 cccccccaac acaccgccga taaaaccgca aaccgccgga acggaagcca caaagcccgc
   154441 tttcagaatc gacatcccgc gcgcctgcac cagataaacc gggaaccagg taatgaaaaa
   154501 gtaagtcagg gcgttgatac agtactgacc gatataaacg ccgatcatca tccgtgaccc
   154561 gagcagctgt ttgatctgcc cccacttcac gctgaacggc actttaactt tggtgttttg
   154621 ctgatccata ttgatcagcg cgccacccgc ggcgatgtac tccagctctt tctgatttac
   154681 gcccggatgt tgatttggct cgtggatgac tttcaaccag ataaagctga tgacaatgcc
   154741 cagaccgccc ataaagaaga agacgtgtga ccagcccact tcatgagtca gccagcccat
   154801 aatcggcgcg aagataaccg ttgcgaagta ttgggcggag ttaaaaatcg acaccgccgt
   154861 tcccctttcc tgcgccggaa accaggccgc aacaatgcgg ctgttgccag ggaaagatgg
   154921 cgcttcagca agcccgacca ggaagcgcag tgtaaacagg gccacgataa tgccgaatcc
   154981 actaaagata tcgacgaagc cttgcagcaa ggtaaacatc gaccagataa agatcgacca
   155041 gaagtagacg cgttttgaac caaaacgatc cagcaaccag ccaccaggga tctgcccgat
   155101 aacataagcc catgagaagg cagagaacac atagcccatt cccacgggat caaggccgat
   155161 atctttggcc atttccgaac cggcaataga aagcgtagcg cggtcgccgt agttgaagga
   155221 tgtgacgata aacaacatca ccactatcca gtaacgagca ttcgtgcgtt tttccacact
   155281 gctcgcagcc tgacttaaag aactcattgt tgcactcctg aaaattcgcg ttagccacgc
   155341 tcactctgga ctgcgacatc gccaggaaat cagaggtgac gtagggtgtt tttgccgttt
   155401 ttataggtcg ttcgccgaat acggcgcgtg tttatatctg gcaatagcag tataaaaagc
   155461 gcgccatagc ggctcaccgt gcaacaacac aacattaatg cgttcaatga ggcccgattt
   155521 tggcattagc cctggacggt ggaatccact tcacggaaat gaaaacaaga acaagaaagg
   155581 aagggttaaa acgaagaaat aaagaagagt atgaaatgga tcgcttgact ccaggcaaac
   155641 gccagtaaaa atccgcgcta tgaagcagtt tttactggca tttgcctgaa aagattcgat
   155701 tcagcaccgc taaaacggca tttaccgctc gctgaacata tcaggacaac atcgtgcccc
   155761 aatgttcaac ccacggattt gattccgttt ccggttccgg gttctcactg gcgtcaatca
   155821 acagcatttc gccaacccgc tgagcgctct gttcctgcaa caaggcatcg aactgtttgc
   155881 cgccattgca gaaattcaca taactactgt cgccgagcgc aatcacgcca taacgcagat
   155941 tcggctggaa gcccagggta tctttaattc cctgaaagag cggcacaatg ctatcaggaa
   156001 ggtcgccctg cccggtcgtg gacgtaacca ccagaacata cttatcctga tagggcagcc
   156061 agtcgcttaa ttcaggatct tcaaataccg ttgctttgtg gccctgcgcg gtcagaatcg
   156121 cttccgcttc ttcggccact aacagcgaat ttccgtacat agtgccgaca aaaataccaa
   156181 tttccgccat accgttttct ccctggatta ggaacttatc tctccatcct gacccgatgg
   156241 cgcactgaac tcaacccttt cattttcagg aagcagaccc cgccagccaa attgtgataa
   156301 cgcctgcatc caggtgtcgt ccaggcccgc gtgaatagcc agcggctcgc cagtaaaagg
   156361 atgcgtcaat gacaactgac tggcatgcag cattaaccgc tgaaggccaa aatgctcagc
   156421 accgctgcga ttctggcgta aatcaccatg tttgctgtcg ccaataatcg ggtgccgcaa
   156481 atgggcaaga tggcgacgaa gctggtgctt gcgtccagtt ttcggctcca gttccaccag
   156541 gccgtagcgc gtggtcgggt aacgtccagt cgctaccggc atttctacgg tcgccagacc
   156601 gcgataatgc gtcactgctg gctgcgggcc tttatcttcg cgggcaaatt tatcagcgat
   156661 tttgtccagt tcttccacca gtggataatc cagcaccgct tcttccatca accagccacg
   156721 cacaatcgca tggtaacgtt tctggatttg gtgctgttca aactgttgtg ccagcagccg
   156781 tccggcttcg ctggataatc ccatcaacaa cacaccagaa gttggtcggt ccagacgatg
   156841 agcagtaaaa acatgctggc ctatctggtc acgcacggtt tgcatgacca ctactttctc
   156901 gtcgcgatcc agccagctgc ggtgaaccag ccagccggag ggtttattta ccgcaaccag
   156961 ccattcatcc tgatagagta tttccagcat tagctcgcat catccgcaaa aagagcatcc
   157021 agtttctcca gctcagccag aataagcgcg cgttgcggat gatcagtcgc cagcgccatt
   157081 tcataatagg gcgcaacagc aaaagcgccc ggtaacggct ggttgttatc taacaaatcg
   157141 tgcattcgcg ggatcagcac ccactgcaac cactccagtg gttccatggt gtccataaag
   157201 aacggttggg tactattaaa ttgatgcggc tggggttcat cgtttcgcca gtgctgatgt
   157261 tcacgcagta acgcttcaag cgcctgcaac tggagacgaa cgcggtcatg agtggtcata
   157321 aagcaacctc aataagaaaa actgccgcga aggatagcag gaataaaaaa agggagcact
   157381 gtattcacag tgctcccggt tcgtttcgca gcattccagc tacttttgtt gctccctgct
   157441 catccttgac aacttttcct ctggccttgc ggccaatcgt tcatcctgaa ctattgcttc
   157501 ctgctcacac caccccgatg tgatacttca tcctgaagtg tccctggcct tcctgaccca
   157561 ccgaatcatc ctgaccggtt ctcattctcc atcctggagg tgtcctttaa cgcgtcctgc
   157621 gtcatcctct tcgcttcatc cagaagcctt tccctgaaac accatcctgg tgtgtccttc
   157681 agaagtgtca tcatcctgat gttcacttcg ttgtctgact ccctgtcgac gaagatagaa
   157741 tcgtcttttt ctcgaagtct tacaaggcgc ttacagacaa tgccttaagg aaaatttcat
   157801 atgaaagtta agaattaaca agcaacatgt tgtttttaaa tgagaataac gattcttatc
   157861 tttttaagta ttcgcttatt tcctggcgat ctcctacaga gtctgtaaga gatctctcac
   157921 aatcagatgg ggtatttgga ttacagaaga ggcttaagtt gattaaggaa ttccgcaaga
   157981 tttgaggcta aatgcgtccg tttacgtgtt cccagcgtct ctttgcacac ttcaccggag
   158041 agattacaca ccgagatgac ctctaactct tcttccagcg tcgcgataaa tagcgtgggc
   158101 ggcagtttta gccttttctg agtcaccaga tgaccaatca gattttcctg cacccgacgg
   158161 aagtcgtctt cactccaggt ttgcagcaat gtcagtttga tatcgccaaa ctgcgcgtgc
   158221 atatccccgg caaactgagt cgtataaaag gtatgaatcg tgggttgtat cacaatatca
   158281 aaagcgcgtt caaccgcgtt tacattttgt tccccggtaa acggctgggg ttgccagtat
   158341 acggcatctt cggtagttga aataatgcac ggtgaaggaa cgccgtacag ttcctcactt
   158401 aacggccagc ttttatgctc ttcatgccac gcatcgcagt agcgtgcagt aaaatctttc
   158461 agggctcgtg cggtcaaatc gtccactaat ttctctcttc acttaaacca gatacacttg
   158521 tcgtttagtt tatctggttt atgacggtga aacatgtctt cttatgcaaa ccatcaggca
   158581 cttgcgggcc tgacacttgg aaaatcaacc gattaccggg atacctatga cgccagccta
   158641 ctgcaaggcg ttccacgcag cctgaatcgc gacccgctgg gtctgaaagc ggataacctg
   158701 ccttttcacg gtacggatat ctggacgctg tatgaacttt cctggctgaa tgcgaaaggt
   158761 ttgccgcaac tcgctgtcgg tcatgttgaa cttgattaca ccagcgtaaa tctgattgag
   158821 tcgaagagtt ttaagctcta tctcaacagt tttaaccaga cgcgttttaa taactgggat
   158881 gaggtgcgcc agacgctaga gcgcgactta agcacttgcg cccagggtaa ggttagcgtg
   158941 gcgttatatc gtcttgatga actggaaggc cagccgatag gtcatttcaa tggcacctgc
   159001 attgatgacc aggatatcac tatcgataac tatgaattca ctactgacta tctggagaat
   159061 gccaccagcg gtgaaaaagt agtggaagag acgcttgtca gccacctgct gaaatcaaac
   159121 tgcctgatca cccatcaacc agattggggt tccatccaaa ttcagtatcg tggacgccaa
   159181 attgacagag aaaaactgct gcgttacctg gtctctttcc gtcatcacaa cgagttccac
   159241 gaacagtgcg tggaacgcat ctttaatgac ctgttacgct tctgccagcc agagaaattg
   159301 agcgtttacg cacgttatac ccgtcgtggc ggtctggaca ttaacccgtg gcgcagtaat
   159361 agcgattttg tcccatcgac cacaagactg gttcggcaat aaattttttc tcaattttgc
   159421 gtgctggatt cacgcagaag gttgtgaaag gtcatcaggc agggctattg taatcaaagg
   159481 gaatgacgat attcgtccca taaggagttt ttcttgatta cacatattag cccgcttggc
   159541 tccatggata tgttgtcgca gctggaagtg gatatgctta aacgcaccgc cagcagcgac
   159601 ctctatcaac tgtttcgcaa ctgttcactt gccgtactga actccggtag tttgaccgat
   159661 aacagcaaag aattgctgtc tcgttttgaa aatttcgata ttaacgtcct gcgacgtgaa
   159721 cgcggcgtaa agctggaact gataaatccc ccggaagagg cttttgtcga tgggcgaatt
   159781 attcgcgctt tgcaggccaa cttgttcgcg gttctgcgtg acattctctt cgtttatggg
   159841 caaattcata acaccgttcg ttttcccaac ctgaatctcg acaactccgt ccacatcact
   159901 aacctggtct tttccatctt gcgtaacgct cgcgcgctgc atgtcggtga agcgccaaat
   159961 atggtggtct gctggggcgg tcactcaatt aacgaaaacg agtatttgta tgcccgtcgc
   160021 gtcgggaatc agttgggcct gcgtgaactg aatatctgca ccggctgtgg tccgggagcg
   160081 atggaagcgc cgatgaaagg tgctgcggtc ggacacgcgc agcagcgtta caaagacagt
   160141 cgctttattg gtatgacaga gccgtcgatt atcgccgctg aaccgcctaa cccgctggtc
   160201 aacgaattga tcatcatgcc agatatcgaa aaacgtctgg aagcgtttgt ccgtatcgct
   160261 cacggtatca ttatcttccc tggcggtgtg ggtacagcag aagagttgct gtatttgctg
   160321 ggaattttaa tgaacccggc caacaaagat caggttttac cattgatcct caccggcccg
   160381 aaagagagcg ccgactactt ccgcgtactg gacgagtttg tcgtgcatac gctgggtgaa
   160441 aacgcgcgcc gccattaccg catcatcatt gatgacgccg ctgaagtcgc tcgtcagatg
   160501 aaaaaatcga tgccgctggt gaaagaaaat cgccgcgaca ctggtgacgc ttacagcttt
   160561 aactggtcaa tgcgcattgc gccagatttg caaatgccgt ttgagccgtc tcacgagaat
   160621 atggctaatc tgaagcttta cccggatcaa cccgttgaag tgctggctgc cgacctgcgc
   160681 cgtgcgttct ccggtattgt ggcgggtaat gtaaaagaag tcggtattcg cgccattgaa
   160741 gagtttggtc cttacaaaat caacggcgac aaagagatta tgcgtcgtat ggacgacctg
   160801 ctacagggtt ttgttgccca gcatcgtatg aagttgccag gctcagccta catcccttgc
   160861 tacgaaatct gcacgtaatc tcccctcccc cggtgacgtt tgttgccggg ttttatcgtt
   160921 tttggtcact tactcatcaa ctcatttcat ttgttatatg aatgtttctt accaacctca
   160981 cgcgacaaat atcaccacag ttaatatgtc atacaattta tgttgaaacg caaacgtttc
   161041 cctattttca taaaccacat tttatcgcca tgaaaaagaa attatcgcca tgattaacta
   161101 aaagtattga tttttccagt tcaacctaca tatattgcgc gccccagaag aagtcagatg
   161161 tcgtttaatg ggcaaatatt gcccttaaat tctcttttac ttttgattta cagagtaaag
   161221 cgttgtgatt atctatcttc caagtagatt attgtatttg ggatcaagat cactgataga
   161281 tacataactt gtgtgtatct ttccgccctc aaattattac ggtggaaaat gattaagcca
   161341 tcgccgatag acagatttca tttttacggt caggcacctt cccgggctga actggctaaa
   161401 agctgaatta tttgcattcc tccaggagaa atagatggaa acgactcaaa ccagcacgat
   161461 tgcgtcgaaa gactctcgta gtgcctggcg caagacagac accatgtgga tgctgggcct
   161521 ttacggcacg gcaatcggcg cgggcgtgct gttcctgcca atcaacgccg gtgttggcgg
   161581 tatgatcccg ctgatcatca tggctatcct tgcattcccg atgacgtttt ttgctcaccg
   161641 cggcctgact cgcttcgtac tgtctggtaa aaacccgggc gaagacatca ccgaggttgt
   161701 agaagaacac tttggtattg gcgcaggtaa actgattact ctgctctact tcttcgctat
   161761 ctacccgatc ctgctggttt atagcgtggc aatcaccaat acagttgaaa gcttcatgtc
   161821 tcaccaactg ggtatgacgc caccgccacg tgcgattctg tcgctgatcc tgatcgtggg
   161881 tatgatgacc atcgttcgct tcggtgagca gatgatcgtt aaagcgatga gtattctggt
   161941 attcccgttt gttggcgtac tgatgctgct ggctctgtac ctgatcccgc agtggaacgg
   162001 cgcagcactg gaaacgctgt ctctggacac tgcatctgca accggaaacg gtctgtggat
   162061 gaccctgtgg ctggcaattc cggtaatggt gttctcgttc aaccactctc cgatcatctc
   162121 ttctttcgcc gttgcgaagc gtgaagagta cggcgatatg gcagaacaga aatgctctaa
   162181 gatcctggca ttcgcacaca tcatgatggt gctgaccgta atgttcttcg tcttcagctg
   162241 cgtactgagc ctgactccgg cagacctggc tgcggctaaa gagcagaaca tctcgattct
   162301 gtcttacctg gctaaccact ttaacgcgcc gatcatcgcg tggatggctc cgattatcgc
   162361 gattatcgct atcaccaaat ccttcctcgg ccactacctg ggcgcacgtg aaggcttcaa
   162421 cggtatggtg attaaatctc tgcgtggtaa aggtaagtct atcgaaatca acaagctgaa
   162481 ccgtatcact gcgctgttca tgctggtaac gacctggatt gttgccaccc tgaacccgag
   162541 catcctgggt atgattgaaa ccctgggcgg cccaatcatc gcgatgatcc tgttcctgat
   162601 gccgatgtac gcaattcaga aagtaccggc aatgcgtaag tacagcggtc acatcagcaa
   162661 cgtattcgtt gtcgtgatgg gtctgattgc aatctccgca atcttctact ctctgttcag
   162721 ctaagtcctt tcgcgccgct ttcgggcggc gcttcctccg ttttaacgcg atgtatttcc
   162781 tatgattagc gtattcgata ttttcaaaat cggcattggc ccttccagtt ctcataccgt
   162841 tggaccaatg aaagcgggta aacaatttac cgacgatctg attgcccgta acctgcttaa
   162901 agacgtgacc cgcgtggtgg ttgacgtgta cggctcgctc tctctgaccg gtaaaggcca
   162961 ccacacagat atcgccataa ttatgggtct ggcgggtaac ctgccggata ccgtggatat
   163021 cgattccatc cctggtttta ttcaggatgt gaatactcat ggtcgcctga tgctggcaaa
   163081 cggtcagcat gaagtggagt tcccggttga tcagtgcatg aacttccatg ccgacaacct
   163141 ttctctgcat gaaaacggta tgcgcattac cgcgctggcg ggcgataaag tcgtttacag
   163201 ccagacttat tactctattg gcggtggctt tatcgttgat gaagagcatt ttggtcagca
   163261 ggatagcgca ccggttgaag ttccttatcc gtacagttcc gctgccgatc tacaaaaaca
   163321 ttgtcaggaa accgggctgt cactctctgg cctgatgatg aaaaacgagc tggcgctgca
   163381 cagcaaagaa gagctggaac agcacctggc gaacgtctgg gaagtcatgc gtggcggtat
   163441 tgaacgcggt atttctaccg aaggcgtgtt acctggcaaa ctgcgcgttc cacgccgtgc
   163501 tgcggcacta cgccggatgc tggtcagcca ggataaaacc accactgacc cgatggcggt
   163561 agttgactgg atcaacatgt ttgcactggc agtgaacgaa gagaacgctg ctggcggtcg
   163621 cgtggtgact gcgccgacta acggtgcgtg cgggattatc ccggccgtgc tggcgtacta
   163681 cgacaagttt atccgcgaag tgaacgctaa ctcactggcg cgttacctgc tggtagccag
   163741 cgccattggt tctctttata agatgaacgc ctcgatttct ggtgccgaag tcggctgcca
   163801 gggtgaagtc ggcgtggcgt gctctatggc ggcagctggt ctggcagaac tgttaggcgc
   163861 aagcccggcg caggtgtgca tcgcggcgga aatcgccatg gagcataacc tcggtctgac
   163921 gtgtgacccg gttgctggac aggtgcaggt accgtgcatc gagcgtaacg ccattgcggc
   163981 agtaaaagcg gtgaacgccg cgcgtatggc gctgcgccgt accagcgagc cgcgcgtctg
   164041 cctcgataaa gttatcgaga ccatgtacga aacaggtaaa gatatgaacg ccaagtaccg
   164101 cgaaacctct cgcggcggcc tggcaatgaa gatcgttgcc tgcgattaat cgctctccag
   164161 aggcctcttt ttgcgaggcc tcttcccgat ttctcatcca gccatagcct gttctggcat
   164221 cgaatgttac ccttatcgcc tgatctttaa gggggttatc gtggctgttc atttgcttat
   164281 tgtcgatgca ctgaatctta ttcgtcgcat tcatgccgtt cagggttcgc cctgtgtcga
   164341 aacctgccag cacgcgctcg atcagctcat tatgcacagc cagccaaccc acgcggtcgc
   164401 cgtttttgat gatgaaaacc gcagtagcgg ctggcgtcat cagcgtttac cagattacaa
   164461 agcgggtcga ccgccaatgc cggaagagtt gcacaacgag atgcctgcat tacgcgccgc
   164521 ctttgagcaa cgcggcgtcc cgtgctggtc cgccagcggc aacgaagccg atgacttagc
   164581 cgccacgctg gcggtcaaag tgacacaggc cgggcatcag gcaacgattg tttcgacaga
   164641 taaaggctac tgtcagttac tttcaccgac attacgtatt cgtgattact tccagaaacg
   164701 ttggctggat gcgccattta tcgataaaga atttggcgtt caaccgcagc agttgcccga
   164761 ttactggggg cttgcgggga tcagcagttc aaaggtaccg ggtgttgcgg ggatcggacc
   164821 aaaaagcgcc acgcagctac tggtcgagtt tcagagtctg gaagggatat atgagaatct
   164881 ggatgcggtt gccgaaaagt ggcgcaaaaa attagaaacc cataaagaga tggcgtttct
   164941 gtgccgcgat attgcccgct tacaaaccga tttgcatatc gacggcaatt tacagcaatt
   165001 gcggttggta aggtaacggc gtgccggatg caaacgatta tcaacacatt gaatttaatg
   165061 cacttatatg ccggataaga cgcggctagc gtcgcatccg gcattatcac atcagcacat
   165121 ttaccaggcg gtatggtaaa gctctacaat atcctcaagc gttgcttcac gcgggttgcc
   165181 accggtacaa acatcatcca gtgccgcctg cgccagtgcc ggaatgtctt ccttgcgtac
   165241 accaacatca cgtaaatgtg gcggaatacc gacatcacgg ttgagagcaa acaccgcttc
   165301 aacggcggca ttacgcgcct cttccaggct cataccttcc actttcacgc ccataacgcg
   165361 cgcgatatcg cggtacttct catcggtaaa gtcagcgtta tagcgcatga catgcggtaa
   165421 caggatggcg ttcgcaacac cgtgtggcgt gttgtaaaac gcgcccagtg gatgcgccat
   165481 accatgcacc aaccctaacc caacattcga gaatcccata cccgcaacat actgcccgag
   165541 cgccatttct tctccggcat ccttatcacc agcaaccgat cctcgcagcg ccccagcaat
   165601 gatttcaatc gctttaatgt gcagcgcatc agttagcgcc cacgcgccac gggtaatata
   165661 cccctcaata gcatgagtga gcgcatcgac acccgtcgcg gctttcagcg ctggaggcat
   165721 accatccatc atgtcagcgt caataaacgc cacctgcggg atatcatgcg gatcaacgca
   165781 aacaaacttg cgccgtttct cttcgtcagt gatcacgtag ttaatggtca cttctgccgc
   165841 agtgcctgct gtggtgggga ttgccagaat cggtacactg ggtttattgg tcggggaaag
   165901 cccttccagg ctacgcacat cggcaaactc cgggttgttg ctgataatgc caatcgcttt
   165961 acacgtatcc tgtggagaac caccaccaat agcgatcagg taatccgcgc cgctattctg
   166021 gaatacatcg agcccttctt tgacgacagt aattgttggg ttaggtacta cgccgtcgta
   166081 aatcgcccat gccagtcctg cggcatccat cttgtcggtc actttcgcca ccacgccgca
   166141 ttgcaccagc gttttatcgg tgacgatcag cgccttctga taaccacggc gtttcacttc
   166201 atcggttaaa gctccaacag cacctcgacc aaaccatgcc gtttcgttca gaatcattct
   166261 gttagccatc atccttctcc ttgttgcttt acgaaattac tcttcaatcc gtaacccgta
   166321 ggttttgaat ttctccagca ctacggcaat ctcttcatcg ctcagcactg gcaccgggtc
   166381 cgtaatcgcc agggtcgtca ggtaaagttg tgccagcact tcaacttcat gcgccagcca
   166441 taacgctttc tccagattcg cctcacaagc gataagccca tgatgttgta acaaagttgc
   166501 cttacgattt ttgagagcca gcgcaacatg ttcagaaagt tcgcgtgttc caaaggtcgc
   166561 ataaggcgcg caaggaatag aattaccgcc agccgccgca atcatgtagt gaatcgcggg
   166621 gatcggtcgg ttaagaatgg aaactgccgt acaatgaacg gcatgattgt gaacaaccgc
   166681 gttggcatcc ggtctgcttt gataggccgc catatggaaa cgccactcgc ttgaggggag
   166741 ttttccttcc tcatgtttgc cgttgccatc aataaagaca atatgcgact ccgtcagttt
   166801 ttcatatgga atacctgtag gcgtaatcag catcccatcc tgataacgta cactgacgtt
   166861 acccgctgtt ccctggttca gccccaggcg agtcatttcc aggcaagtgt caataatctg
   166921 acgagcaagt ttatttcgtt ccattagcta cctctctctg attcaaaaca gggcaataat
   166981 gttgttcctt tcacactatt gaattagccg tttaattact caccatattc ttcctgatta
   167041 accagaaaga aattcacaag cttatatttt gtgacctggt tcaactaatc acagtaaata
   167101 actgcaagtt ctctttttat aaccccatta aaaatgaccg ctcttaaaaa tatttatcaa
   167161 aacggtcatt tttctactcc tccctgccag gaatgcccgt tttcggcaca aacaattaat
   167221 acggtcatct ggtttgtgtt ttttatgatt tattttctga aacgggcatg aaatttcgat
   167281 tattaaagtg atggtagtca cataaagtca ccctccggct aataagtgtg accgccgtca
   167341 tattacagag cgttttttat ttgaaaatga atccatgagt tcatttcaga caggcaaata
   167401 ttcactgata tgaagcccga actcgctggt tttgcacttt tgaaaacata accgattacg
   167461 tgcttaagct tctgaaccta agaggatgct atgggaaaca catcaataca aacgcagagt
   167521 taccgtgcgg tagataaaga tgcagggcaa agcagaagtt acattattcc attcgcgctg
   167581 ctgtgctcac tgttttttct ttgggcggta gccaataacc ttaacgacat tttattgcct
   167641 caattccagc aggcttttac gctgacaaat ttccaggctg gcctgatcca atcggccttt
   167701 tactttggtt atttcattat cccaatccct gccgggatat tgatgaaaaa actcagttat
   167761 aaagcaggga ttattaccgg attgttttta tatgccttcg gcgctgcatt attctggccc
   167821 gccgcagaaa taatgaacta caccttgttt ttagttggcc tatttattat tgcagccgga
   167881 ttaggttgtc tggaaactgc cgcaaaccct tttgttacgg tattagggcc ggaaagcagt
   167941 ggtcacttcc gcttaaatct tgcgcaaaca tttaactcat ttggcgcaat tatcgcggtt
   168001 gtctttgggc aaagtcttat tttgtctaac gtgccacatc aatcgcaaga cgttctcgat
   168061 aaaatgtctc cagagcaatt gagtgcgtat aaacacagct tggtattatc ggtacagaca
   168121 ccttatatga tcatcgtggc tatcgtgtta ctggtcgccc tgctgatcat gctgacgaaa
   168181 ttcccggcat tgcagagtga taatcacagt gacgccaaac aaggatcgtt ctccgcatcg
   168241 ctttctcgcc tggcgcgtat tcgccactgg cgctgggcag tattagcgca attctgctac
   168301 gttggcgcac aaacggcctg ctggagctat ttaattcgct acgctgtaga agaaattcca
   168361 ggtatgacag caggctttgc cgctaactat ttaaccggaa ccatggtgtg cttctttatt
   168421 ggtcgtttca ccggtacctg gctcatcagt cgcttcgcgc cacacaaagt cctggcagcc
   168481 tacgcattaa tcgctatggc actgtgcctg atctcagcct tcgctggcgg tcatgtgggc
   168541 ttaatagccc tgactttatg cagtgccttt atgtcgattc agtacccaac aatcttctcg
   168601 ctgggcatta agaatctcgg ccaggacacc aaatacggtt cgtccttcat cgttatgacc
   168661 attattggcg gcggtattgt cactccggtc atggggtttg tcagtgacgc agcgggcaac
   168721 atccccactg ccgaactgat cccggcactc tgcttcgcag tcatctttat ctttgcccgt
   168781 ttccgttctc aaacggcaac taactgaaca tattttccga ataaagtgag gaatcagtaa
   168841 tgaaaaaaat cagcttaccg aaaattggta tccgcccggt tattgacggt cgtcgcatgg
   168901 gtgttcgtga gtcgcttgaa gaacaaacaa tgaatatggc gaaagccacg gctgcactgc
   168961 tgaccgagaa actgcgccat gcctgcggag ctgccgtcga gtgtgtcatt tccgatacct
   169021 gtatcgcggg tatggctgaa gccgctgctt gcgaagaaaa attcagcagt cagaatgtag
   169081 gcctcaccat tacggtaacg ccttgctggt gctatggcag tgaaaccatc gacatggatc
   169141 caacccgccc gaaagccatt tggggcttta acggcactga acgtcccggc gctgtttacc
   169201 tggcagcggc tctggcagct cacagccaga aaggcatccc ggcattctcc atttacggtc
   169261 atgacgttca ggatgccgat gacacatcga ttcctgccga tgttgaagaa aaactgctgc
   169321 gctttgcccg cgccggttta gcagtcgcca gcatgaaagg taaaagttat ctgtcgctgg
   169381 gcggcgtttc gatgggtatc gccggttcca tcgttgatca caacttcttt gaatcctggc
   169441 tgggaatgaa agtccaggcg gtggatatga ccgaactgcg tcgccgtatc gatcagaaga
   169501 tttacgacga agccgaactg gaaatggcgc tggcctgggc tgataaaaac ttccgctatg
   169561 gcgaagatga aaataacaaa cagtatcaac gcaatgccga gcaaagccgc gcagttctgc
   169621 gcgaaagttt actgatggcg atgtgtatcc gcgacatgat gcaaggcaat agcaaactgg
   169681 ccgatattgg tcgcgtggaa gaatcacttg gctacaacgc catcgctgca ggcttccagg
   169741 ggcaacgtca ctggaccgat caatatccca atggcgatac cgctgaagcg atcctcaaca
   169801 gttcatttga ctggaatggc gtgcgcaaac cgtttgtcgt ggcgaccgaa aacgacagtc
   169861 ttaacggcgt ggcaatgtta atgggccacc agctcaccgg caccgctcag gtatttgccg
   169921 atgtccgtac ctactggtca ccagaagcaa ttgagcgtgt aacggggcat aaactggacg
   169981 ggctggcaga acacggcatc atccatttga tcaactccgg ttctgctgcg ctggacggct
   170041 cctgtaaaca acgcgacagc gaaggtaaac cgacgatgaa gccgcactgg gaaatctctc
   170101 agcaagaggc tgacgcttgc ctcgccgcta ccgaatggtg cccggcgatc cacgaatact
   170161 tccgtggcgg cggttactct tcccgcttcc ttaccgaagg cggcgtcccg ttcaccatga
   170221 ctcgtgtcaa catcatcaaa ggcctgggac cggtactgca aatcgcggaa ggctggagcg
   170281 tggaattgcc gaaggatgtg catgacatcc tcaacaaacg caccaactca acctggccaa
   170341 ccacctggtt tgcaccgcgc ctcaccggta aagggccgtt tacggatgtg tactcggtaa
   170401 tggcgaactg gggcgctaac cacggagttc tgaccatcgg ccacgttggc gcagacttta
   170461 tcactcttgc ctccatgctg cgtatcccgg tatgtatgca caacgttgaa gagaccaaag
   170521 tgtatcgtcc ttctgcctgg gccgcgcacg gcatggatat tgaaggccag gattaccgcg
   170581 cttgccagaa ctacggcccg ttgtacaagc gttaatacat gactccctga tgtgatgccc
   170641 ggtcgctccg gctaccgggc ctgaacaagc aagagtggtt agccggataa gcaatgttat
   170701 ccggctatat tgcaggagcg attatgaaac aagaagttat cctggtactc gactgtggcg
   170761 cgaccaatgt cagggccatc gcggttaatc ggcagggaaa aattgttgcc cgcgcctcaa
   170821 cgcctaatgc cagcgatatc gcgatggaaa acaacacctg gcaccagtgg tctttagacg
   170881 ccattttgca acgctttgct gattgctgtc ggcaaatcaa tagtgaactg actgattgcc
   170941 acatccgtgg tatcgccgtc accacctttg gtgtggatgg cgctctggta gataagcaag
   171001 gcaatctgct ctatccgatc attagctgga aatgtccgcg aacagccgtg gtaatggaca
   171061 atattgaacg gttgatctcc gcacagcagt tgcaggctat ttctggagtc ggagccttta
   171121 gtttcaatac gttatataag ttggtgtggt tgaaagaaaa tcatccacaa ctgctggaac
   171181 gcgcgcacgc ctggctcttt atttcgtcgc tgattaacca ccgtttaacc ggcgaattca
   171241 ctactgatat tacgatggcc ggaaccagcc agatgctgga tatccagcaa cgcgatttca
   171301 gtccgcaaat tttacaagcc accagtattc cacgccgact cttccctcgt ctggtggaag
   171361 cgggtgaaca gattggtacg ctacagaaca gcgccgcagc aatgctcggc ttacccgttg
   171421 gcataccggt gatttccgca ggtcacgata cccagttcgc cctttttggc gctggtgccg
   171481 aacaaaatga acccgtgctc tcttccggta catgggaaat tttaatggtc cgcagcgccc
   171541 aggttgatac ttcgctgtta agtcagtacg ccggttctac ctgcgaactg gatagccagg
   171601 cagggttgta taacccaggt atgcaatggc tggcatccgg cgtgctggaa tgggtgagaa
   171661 aactgttctg gacggctgaa actccctggc aaatgttgat tgaagaagct cgcctgatcg
   171721 cgcctggcgc agatggagtg aaaatgcagt gtgatttatt gtcgtgccag aacgctggct
   171781 ggcaaggcgt aacgcttaat accacgcggg ggcatttcta tcgcgcggcg ctggaagggt
   171841 taaccacgca attacagcgc aatctacaga tgctggaaaa aatcgggcac tttaaagcct
   171901 ctgaattatt gttagtcggc ggaggaagtc gcaacacatt gtggaatcag attaaagcca
   171961 atatgcttga tattccggta aaagttctcg acgatgccga aacgaccgtc gcaggagctg
   172021 cgctgtttgg ttggtatggc gtaggggaat ttaacagccc ggaagaagcc cgcgcgcaga
   172081 ttcattatca gtaccgttat ttctacccgc aaactgaacc tgaatttata gaggaggtgt
   172141 gaaatgctga aaacaatttc gccgttaatt tctcccgaac tattgaaagt gctggcagag
   172201 atggggcatg gagatgaaat tattttttcc gatgctcact ttcccgccca ttcgatggga
   172261 ccgcaggtga tccgcgctga tggcctgttg gtgagcgact tgctccaggc gattatcccg
   172321 ttatttgaac tggacagtta tgcaccaccg ctggtgatga tggcggcggt agaaggtgac
   172381 actctcgatc ctgaagtaga acgacgttac cgtaatgcgc tttcactaca agccccgtgt
   172441 cctgacatca tccgcatcaa tcgttttgcg ttttatgaac gggcgcaaaa agcctttgcg
   172501 atcgttatca caggcgaacg agcgaagtac gggaatattc ttttaaaaaa aggggtaaca
   172561 ccgtaatctc ataccggtac gcccgcatga cgcgggcggt tatcgaatga tggggtgaaa
   172621 aatatgaaag cggcacgcca gcaagcgata gtcgacctgc tgctgaacca taccagcctg
   172681 accacggaag ctctctctga acagctaaag gtcagtaaag aaaccattcg tcgcgatctc
   172741 aatgaattac agacgcaggg taaaattctg cgcaatcatg ggcgcgctaa atatatccac
   172801 cgtcaaaatc aagacagtgg cgatcccttt cacatccggc tgaaaagcca ttatgcgcat
   172861 aaagcagata tcgcgcgcga ggcgctcgcg tggattgaag aagggatggt gatagcctta
   172921 gacgccagtt caacctgctg gtatctggca cgccagttgc ctgacatcaa catccaggtc
   172981 ttcaccaata gccatccgat ttgccatgaa ctcggtaaac gcgaacgcat tcaactgatc
   173041 agttccggcg gcacacttga gcgcaaatat ggctgttacg tcaatccctc gctgatttcc
   173101 caacttaaat cgctggaaat cgatctgttt attttttctt gtgaagggat cgatagcagc
   173161 ggcgcactgt gggactccaa tgccatcaac gctgattaca aatcaatgtt attaaaacgt
   173221 gccgcgcaat cgttgttatt gattgataaa agtaaattta atcgttcagg ggaagcccgc
   173281 atcgggcatc tggatgaggt cacgcacatt atttctgatg agcgccaggt tgcaacttct
   173341 ttggtaacag cctgacggaa agggtagcag gccggagacg acgccccggc cttgcctgtt
   173401 atcgctcgtc gcgacgacca cccaccgcag cccagatacg gcggacgtgc accgtcactt
   173461 cttcgcgatc gtgatacaac tgccgcgcct gaatctgagc atttatgcca tgttcatcaa
   173521 gctgtgcctg aatatacgcc agattgtgtg acacttcttc gtagcgtttt ttcatcggca
   173581 gtttgagatt gaagatagtt tcacggcacc agccattaac cagccactgc gccattaatg
   173641 ccgcaacttt cgccggtttt tcaaccatat cgcataccat ccaggagata ttgctgcgtg
   173701 tcggacggaa tttgaaaccg tcttcccgca gccacgtcac ctgcccggta tccatcagac
   173761 tttgcgccat cgggccgttg tcgacggaat aaacccacat gttgcgcttc accagttggt
   173821 aggtccagcc gcctgggcaa gcgcccaaat ccaccgccca catcccgttc gccaggcgtt
   173881 catcccactc atccgcggga ataaacacat gaaatgcctc ttccagtttg agcgtggaac
   173941 gactcggcgc atctgccgga aatttcaggc gcggaatgcc catatagaac ggcgaattat
   174001 tgttgctgta tgagtaaccg gtatagcaac agcctggtgc aataaagaat acatgcacaa
   174061 ccggacgctt cggcgtttca tagttcgcca gcacccccgc atcacgcaag gcagcgcgta
   174121 gcggcacggt gaatttacgg cagaatttca gcaactcttt gctttcgttg gtatcggcaa
   174181 cttcaacacg cagttcaccg cccttctcta ctacaccctg caacatgcca acaatggggg
   174241 taatacgatc ttctggcggc aaatgctgca ggagttcccc cactacaaac cactggcggg
   174301 caaaaattaa tgaactgaac ggcagctcac ggattaactt atcgccatca tcaggttgat
   174361 aacattcata aatcacataa cccgcattct ctttcacgcg ggcaaaaccg aaaatttccc
   174421 gctggccggc tttatcggta atttctgcgg cgcactcttt ttcaaagccc ggacggcaca
   174481 gcaatacaac cttattcatg acttacgccc ttgcgcttta aacggatagc accaactaac
   174541 attaacgccc aacccgcaag gaagctcacg ccgccaaccg gtgtaacaaa cgcccacaaa
   174601 cgcagatggg acagcgccag gcaataaagg ctgccgctga acagcaccgt gcctaacgcg
   174661 aggaaaacgc tactccagta aaaccagata ctgatgcgac gctgcattgc caccgccaga
   174721 cctaagatcg ccagcgtatg aaacgcctgg tattcgaggc cggtctggat ccagcccatc
   174781 tcaacggccc ccatggtttt acttaacaca tgcgcgccaa aagcgcccag agccacaaaa
   174841 atgaagccgc taatggcggc gaaaatcagc ataaaacggc tggtcatggt cgtaccctac
   174901 gtaaattatt gttcataacg aaagcggaat ttttcttgtt cagcagcggc tttcgccagg
   174961 atccattggc gaaaggcggc tattttaccc agttctgcct ggctgtcatg acaaaccaga
   175021 taaaaagcgt ttttactgac cagaacatca ttaaacgggc aaacaagacg tccggcttca
   175081 atttcagatt gcgccatcac gttatttgcc agcgccactc cctgcccgtg gatagccgct
   175141 tgcagcacca tggcgctatg gctaaaaatt ggcccttgct gaacgttgat atgatttaac
   175201 cccaactgtc gggtatatgt ctgccagtca cggcgtgacg catcatgtaa taacgtatgt
   175261 ttagccagat cttccggggt cttcaagggg ttttcgccag tcagcagtag cggcgagcac
   175321 accggcaata aatattcggc gtacagtttt tccacccgta gccccggcca gttgccccga
   175381 ccataaaata tcgccacatc aacatcatcc gccagcttat cttcctgacg atcaaccgcc
   175441 tggattcgaa catcaattcc cggataagct gaattaaagc tggaaagtcg cggaaccaac
   175501 caatgaatgg cgaaactggg gagtaaactg accgtcaacg cccccttagc gctacgggcc
   175561 tggagtttac gcgtcgcttc ggttaattgc gaaaatatct ctttgatatc gaggaaatag
   175621 ctttgccctt cctcggtcag caggagtgaa cgattacggc ggcggaacag ttttagcccc
   175681 agaaaatcct caagagactt gatttgatga cttactgcgg cctgggtcac aaaaagctct
   175741 tctgctgcgc gagtgaaact taaatggcgt gctgcggcat caaaaactcg taaggcattt
   175801 agcggtggta atcgtttaga catggctttt aaactttgat gttaaatgaa tttaacaatt
   175861 agattacact gtgtaaccta ttagtttttt taatctgagc cattataaat tgtccgttga
   175921 gcttctacca gcaaatacct atagtggcgg cacttcctga gccggaacga aaagttttat
   175981 cggaatgcgt gttctggtga acttttggct tacggttgtg atgttgtgtt gttgtgtttg
   176041 caattggtct gcgattcaga ccatggtagc aaagctacct tttttcactt cctgtacatt
   176101 taccctgtct gtccatagtg attaatgtag caccgcctaa ttgcggtgct tttttttacc
   176161 ttgcgatcgc gaattactga tccagttcga ccatctcttt cacgtcggta cggttgatct
   176221 gctgtttgtt gccattagcg tctttatacg aaatcatacc ggtatcgtta tcagtctgtg
   176281 gtttgccgtc agagacgatg gtacgtccgt cattggtgtg catcacatag ttcgaaccgg
   176341 aacaggcgct cagggcaaaa gtcagcatac aggcagaaat aattgcggca gtctttttca
   176401 tcatcttctc cttaaagcga ttaataaatc ttaatagtat tgattaacag gctaaaatta
   176461 acgcctaaca ctattcagca tatgttactg acgcggcttc gccaggatat ccagataatt
   176521 ctgatggtta gcactctcct tgtatcaaag tgaattttgc gtcacgatcg gtgcatcaag
   176581 ccgaggagta ccatgaacgt ttttaatccc gcgcagtttc gcgcccagtt tcccgcgcta
   176641 caggatgcgg gcgtctatct cgacagcgcc gcgaccgcgc ttaaacctga agccgtggtt
   176701 gaagcctccc gacagtttta tagcctgagc gccggaaacg tccatcgcag ccagtttgcc
   176761 gaagcccaac gcctgaccgc gcgttacgaa gctgcgcggg aaaaagtggc acaattactg
   176821 aatgcatcgg atgacaaaaa tatcgtctgg acgcgcggca ccactgaatc catcaacatg
   176881 gtggcgcaat gctatgcccg tccgcgtctg caaccgggcg atgaaattat tgtcagtgtg
   176941 gcagaacacc acgccaacct cgtcccctgg ctgatggtcg cccaacaaac gggggccaaa
   177001 gtggtgaaat tgccgcttaa tgcgcagcga ctgccggatg tcgatttgtt gccagaactg
   177061 attactcccc gtagtcggat tctggcgttg ggccagatgt cgaacgtcac tggcggttgc
   177121 ccggatctgg cgagagcgat tacttttgct cattcagccg ggatggtggt gatggttgat
   177181 ggtgctcagg gggcggtgca tttccccgcg gatgttcagc aactggatat tgatttctat
   177241 gctttttcag gtcacaaact gtatggtccg acaggcatcg gcgtgctgta tggcaaacca
   177301 gaactgctgg aagcgatgtc gccctggctg ggcggcggca aaatggttca cgaagtgagt
   177361 tttgacggtt tcacgactca atctgcgccg tggaaactgg aagcaggaac gccaaatgtc
   177421 gctggcgtca taggattaag cgcggcgctg gaatggctga cagattacga tatcaaccaa
   177481 gccgaaagct ggagccgtag cttagcaacg cttgcagaag aagcgctggc gaaacgtcca
   177541 ggctttcgtt cattccgctg ccaggattcc agcctgctgg cctttgattt tgctggagtt
   177601 catcacagcg atatggtgac actgctggcg gagtacggta ttgccctgcg cgccgggcag
   177661 cattgcgctc agccgctact ggcagaatta ggcgtaaccg gcacactgcg cgcctcattt
   177721 gcgccatata atacaaagag tgatgtggat gcgctggtga atgccgttga ccgcgcgctg
   177781 gaattattgg tggattaatg acaaacccgc aattcgccgg acatccgttc ggcacaaccg
   177841 taaccgcaga aacgttacgc aataccttcg caccgttgac gcaatgggaa gataaatatc
   177901 ggcagttgat catgctgggg aaacagcttc cggctttgcc agaggagtta aaagcgcagg
   177961 ctaaagagat tgccggatgc gaaaaccgcg tctggctggg atataccgtg gctgaaaacg
   178021 gcaagatgca tttctttggc gacagcgaag ggcgcattgt gcgcggcctg ttggcggtgt
   178081 tgttgactgc cgttgagggg aaaaccgctg ccgaattgca ggcacagtcg ccgctggcat
   178141 tgtttgatga gctgggatta cgtgcgcaac ttagcgcctc acgcagccag gggttgaatg
   178201 cgttaagcga ggcgattatc gctgcggcga agcaggttta agcacagaac caggtcggat
   178261 aagacgttcg cgtcgcatcc gacctgattg tttacccctg acgcgccgct ttcgccatca
   178321 tcttcttcag cgcatgagaa accgcaacaa agccaaaagt ggcggtcacc atcgtcgccg
   178381 cgccaaatcc tgaggcacaa tccatccgct ttggcccttc cgccgtggct ttcatcgcac
   178441 agacggtgcc gtctgactgc gggtacacca gcgcttcggt agagaacacg caatccacgc
   178501 cgagcttacc tttactgttt ttcactacgc caaaatcgct tttcaggcgc tcgcgcaact
   178561 tcgccgccaa cgggtcctga atcgttttcg ccagatcggt aacctgaatc tgcgtcgggt
   178621 caatctgccc accagcgcca ccggtcgtga ccagcgggat tttattgcgc cgacaataag
   178681 caatcagcgc cgctttgggc cgtacactat caatagcatc aatcacgtac gaataaccgg
   178741 cattcatata ttgcgctacg ttatccggcg tcacgaagtc atccactacc gttacacggc
   178801 actccgggtt aatctggcga atacgctccg ccatgacttc cgcttttgcc agcccgacgt
   178861 tatcgcgcag agcgtgaatt tgccgattgg tattggtgac gcacacatca tccatatcga
   178921 taagcgtgat tgcaccaatc cccgtgcgcg ctagcgcttc cgccgcccag gaaccgacac
   178981 caccgatacc aaccacacaa atatgcgcgt cagcaaacag ttgcaatgct ttttcaccat
   179041 acagacgcgc tgtgccacca aaacgctgac gccatgcatc actaattacc acagacatag
   179101 cacctcagaa ttaaaaaggg tgaggttacc cctcaccctg tcatatccgt aaaaacggca
   179161 tacagaatat cacatcagcc gctaaagacg ttacctgcgc ccggggcggt tttcagcacc
   179221 cagacacgtc catagtggtt gtaccaacct gcgcggtgtc cggcttccgg cccgatccct
   179281 tgatagatat cgaagtgttg gcctttgatt gcgccaccga catccagcgc caccatcaga
   179341 cgcaattcgt actgaccgtt aaatttgccg ttattatcca gcagcggcac ttctgccagc
   179401 aaggtagtac ctggcggaat aattgaacga tcggaggcaa cagaagcacg gccaaccagc
   179461 ggcaccgcac ttgccccttt caccggtgca aaagattgcg gtttaaagaa gacgaaagac
   179521 gggttctgtt ccagcagctc gcgaacctca gcttcactgt gtgtttcgcc ccagtgacga
   179581 atcgcctgca tcgacatatc ttcttttttc acttcgccac ggtcgatcaa caccttacca
   179641 atgctgcgat aggcatgacc gtttttccct gcatagctga aaaagttaag cggactgcca
   179701 tcaccaaagt cgatataccc gctaccctgc acatccataa tgaagttatc catcagggag
   179761 ttactgtaag cgagaatata tttatcactc agcgctcctg cgtagatctc cgcacgagac
   179821 ggcagacgac cacgttttgg cggcatacgg taaatcggat actggaactc gccctgacgg
   179881 gtatggcgcg cctgaattac cggcgtgtaa tagcctgtaa actgcacgtt accatagttg
   179941 tcgacacctt ccatctgcca ggcatcaatg ccgaactggc gcatattgcg ggtatcaccg
   180001 cctgcgcgca gccactcttg caccgcgtta taaacattac tctggttgcc atacagacgc
   180061 ggtgacgaat tacggatatg gttaatttgc tcggcaaaat caccggcatt aatcggcgcg
   180121 ccaacggcat ctggctggtt caccagagag aaaggctggg taaatttccc gtctttatat
   180181 tgctgtccgc gatcggttgg tttggaagag caggcggcaa gcattgccac aaccgtgccc
   180241 ataagaaggt actttaccca acgtcctttc attgttctct tcttcaggtt aaaaaataag
   180301 gcgcaacgaa gataacaaac caccgcgttt aatgaaatga gcagcctctc cctgacgcaa
   180361 attttgcaca aaaaataggc tctagtgatt tgtttttgtt caaaatcatg ccaaatccgt
   180421 gatcggggta aaaaaaaggt tgcatgaaaa cgcgagcaga gtatagtgcg catccacgga
   180481 cgcggggtgg agcagcctgg tagctcgtcg ggctcataac ccgaaggtcg tcggttcaaa
   180541 tccggccccc gcaaccaatt aaaatttgat gaagtaaagc agtacggtga cgcggggtgg
   180601 agcagcctgg tagctcgtcg ggctcataac ccgaaggtcg tcggttcaaa tccggccccc
   180661 gcaaccaatc aaaatttgat gaaataaagc agtacggtga cgcggggtgg agcagcctgg
   180721 tagctcgtcg ggctcataac ccgaaggtcg tcggttcaaa tccggccccc
//
LOCUS       DAPOXO010000002       128546 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPOXO010000002 DAPOXO010000000
VERSION     DAPOXO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 128546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128546
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.002"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            152..1912
                     /gene="tssF"
                     /locus_tag="ROH59_000187"
     CDS             152..1912
                     /gene="tssF"
                     /locus_tag="ROH59_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HDX4802730.1"
                     /translation="MDDLTQRYFEAEMRYLREAGKEFAQAYPDRAAMLNLDKPGARDP
                     YVERLFEGFAFLMGRLREKLDDDLPELTEGLVSLLWPHYLRTIPSLSVVELTTDHQQM
                     KQSDTLKEFQVLSRPIGERRTRCVYSATRDITLHPLALPDVSLQYEPDGRSVIRLRFE
                     CGPLVGDWSQIDLSRLPLYLSADSPVACALHRALTLGTQQFWLRLPGQGRRVLDAHFS
                     PMGFDDDDRLWPKGESAFSGYQLLLEYFTFREKFMFVALNGLEQVAWPEGITGFEIDV
                     LLNENWPHDLPFDSDNIRLHCVPVINLFPLEADPLHLSPLENEFLLRPMRIQDGHTEI
                     YSVDNIISSRHTGSQAYVPFSSFRHRGGMLRHDAPERYYHTRVKRGPSGLHDTWLILG
                     GDAFDTDRMLEDETLSLSLTGTNGQLPRKALQSTLLDTPVHASQNVLRVRNLCAPTQP
                     CYPPARDRFHWRVLSHLGSNFLSMMDNAEILRGTLALYDWTESEMNRRRLAAIVDVQH
                     SLIQRFERGFLLRGVDIQVTLDSNGFAGEGDITLFGELLHRFFALYADIHLFTQLTLI
                     LQPTGKCLQWTEHHSQRVPG"
     gene            1876..2955
                     /gene="tssG"
                     /locus_tag="ROH59_000188"
     CDS             1876..2955
                     /gene="tssG"
                     /locus_tag="ROH59_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HDX4802731.1"
                     /translation="MDRASQPARTGLTDRLAPDIARINFYRFCQLLEQRQQNAPLGST
                     DSPAADAVRFRPHPGMGFPVSELKNVERDVDNPDAPPTVRTTFLGLYGVDSPLPTAYL
                     DYITQRHDGHDAVMAFLDIFNHRFITQYYRIWRKYNYPASFEAGAVDDISRCLLGLIG
                     LGIPGSENHIATPVSRFLALLSVMRLPTRTAEGVTALVGLLAPLTKATVVPHDPQPVI
                     LPAPAGLSKNSPISLKTRTLLGRTGTDVNSQLLLKLYTEDAAEARGWLPGGQLHSDLL
                     VLLRVYLGWRCQARLQLTLPVSLLPAARLGKQRVQISRTGILRASFAAPATGTVTVSL
                     GRYQGLIPAFSIRNRESMTHVSYSF"
     gene            2936..3472
                     /gene="tssJ"
                     /locus_tag="ROH59_000189"
     CDS             2936..3472
                     /gene="tssJ"
                     /locus_tag="ROH59_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HDX4802732.1"
                     /translation="MFPIRFKRPALLCMAMLTVVLSGCGLIQKVVDESKSVASAVFYK
                     QIKILHLDFFSRSALNTDAEDTPLSTMVHVWQLKTREDFDKADYDTLFMQEEKTLEKN
                     VLAKHTVWVKPEGTASLNVPLDKETQFVAIIGQFYHPDEKSDSWRLVIKRDELEADKP
                     RSIELMRSDLRLLPLKDK"
     gene            3476..3904
                     /gene="tssE"
                     /locus_tag="ROH59_000190"
     CDS             3476..3904
                     /gene="tssE"
                     /locus_tag="ROH59_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HDX4802733.1"
                     /translation="MSTPSLYEMLTFSFSGELPLEQVRERDQLILSVMDNMQRIINCR
                     AGTLAHLPDYGLPDLSLIHQGMAAGIHGLMRQIEETLLRYEPRLSQIQVELLPQPRPG
                     HLNYLIHAQLPDTGWIRFDGVFSPEGRIVLRHLKQQERAY"
     gene            3904..5280
                     /locus_tag="ROH59_000191"
     CDS             3904..5280
                     /locus_tag="ROH59_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ImpA family N-terminal
                     domain-containing protein"
                     /protein_id="HDX4802734.1"
                     /translation="MASNANFISQFVMGGDPCTYKESGELQAEMSKLTHPARPDVDWR
                     QVEKLCLALFRQNGVELQTLVCYVLAITRRQGLAGMADGLGSLDILLQRWADFWPVQV
                     HSRISLLSWVTEKMQQALRTLDIQYQDLPQIYRCVQHLSAIETTLQQCELWHMTKLDV
                     LAGQFRNTALRLERLAPQGAETTITPPELPRREMNQPKKSEESPQPVFATRPAQQNDK
                     DASPPVSSPEISRQRTWPIFMAGMVVMAGLGGTGLWGWSQLNQPDALIQRIQLSVMPL
                     PQSLESGELAKLDVKDKALLAQDRTIAASQMQLEQLNKLPARWPLEQGYRQLRQLDAL
                     WPDNPQVRALNVQWRKQRELSALSAEALNGYAQAQSQLQRLSAQLDALDERKGRYLTG
                     SELKTAVYGIRQSLKEPPLEELLRQLEEQKQTGEISPTLLTQIDTRLNQLLNRYVILL
                     DTKVEQSQ"
     gene            complement(5580..6527)
                     /locus_tag="ROH59_000192"
     CDS             complement(5580..6527)
                     /locus_tag="ROH59_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001361319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDX4802735.1"
                     /translation="MKNVLVTVPSFSARCVSASKLLRENNFNLIIKNNVEHLLKSEST
                     ALRESICAVIAGKDCYQADTLSLLSGVKIISRFGTGIDNIDLRAAQQSGIVVNNAVGI
                     NSNAVAEFIIGLIFASMRNIPGSYHAMQNGYWGESHGCELQGKRIGLVGYGNIGKILA
                     KRLSGFDVELLAFDKQPDYQVADKAGVQFVSIEDIFMQSHAIIVLLPFSSELENFISH
                     KYLSMMRNGALIINAARGKLLDEGALLQVIEERNVFAALDVFSSEPLAQFSPLLHAKN
                     IITTPHIAAATVESYQQTGIHVAQSIIDYFAGRKIKNVL"
     gene            complement(6599..7195)
                     /locus_tag="ROH59_000193"
     CDS             complement(6599..7195)
                     /locus_tag="ROH59_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDX4802736.1"
                     /translation="MNNTDLIHLIKHFMRNEHKAVEEVIDSPLSEVANLIKVLQSCQG
                     KVVFIGVGKSGIIARKLAATFASTGTPSFFVHGTEAVHGDLGMVAKDDVVILISNSGE
                     TAEILATLPSLKKMGNYLISFTRSHHSSLAISCDLSVEIPVKSEADNLGLAPSCSSTV
                     VLVVGDAVALALSELKKFTRADFGLYHPGGALGIKANS"
     gene            complement(7198..8373)
                     /locus_tag="ROH59_000194"
     CDS             complement(7198..8373)
                     /locus_tag="ROH59_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000382418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDX4802737.1"
                     /translation="MDVFNTPVSRKGTYCTQWDFCEDRFGVKDVLPFSISDMDLPIPD
                     AITRALKKRLEHPILGYSRWQHGEYLNAIVNWYYQQYQTDIKPEWITYSPSVMYSIAK
                     AIELLTSHGDNILVFTPVYNAFFDVIKHSERNILTASLIIKNEGSYAINWQDFDLKIK
                     SAKMVLLCNPHNPTGTVWSEEELHKIAASCTRHNVWLCSDEIHSDFVFNRSFTSALKI
                     KKEKVVVFNSISKTFNVPALTGSYMISTDDNFNHKFRTISRYRDFVNSPSVLNIIATI
                     IGYNECEGWLKSLKAHIASNIQFTQQYLNENIPELIVRPADGCYFSWIDCSAIGYPFD
                     EFYSRLIHEGKVGIMAGHVYGTEGEGYLRLNLACSREKLYMGLTRLVSVIKNINQGE"
     gene            complement(8373..9953)
                     /locus_tag="ROH59_000195"
     CDS             complement(8373..9953)
                     /locus_tag="ROH59_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDX4802738.1"
                     /translation="MKQKKAWSFFQSLGKAFMYPIALLSVCGMMLGLGSGLASDDMAK
                     LIPFLAIPIIKTILDFIVSLGLFAFVNLPVLFAIAIPLGLLKDKEDKAYGAFSGLIGF
                     MAMHLGTNFYLKQHDLLVVADQMSTHGQTIILGIQSYNTSVLGGIVAGLLVASMYKKI
                     VNLRIPESLGFYSGPRLVPIITLIVMSGFGLIIPFIWPPFFNLFMLIGHWISTSGPVG
                     YFFYAVAERVTIPFGLNHLVTSVFRFTPIGGSAVIGGEEYYGTLNMFMAYVKENAVIP
                     LDLAGKMEQGKLMIQYGLAGAALAMYRTAHAQNRKAIKALLISGVLTVIIGGVSEPIE
                     FLFLFVSPLLFVFHAFMNGFANMVLPYMGVKMGFTGDLIQFISFGVLRGTRTGWPIAV
                     CVEVAYFFIYYFVFRWTILKFNLMTVGREESSPVTLNAHEDTAIADIPTPDKSELQAA
                     EQMVKALGGKENIKSLDNCVTRLRLTIADMGLIDEVAIKIAGGIAVVKLDQNTLQVII
                     GTKVIALRRDMDNYMGIY"
     gene            complement(9985..10809)
                     /locus_tag="ROH59_000196"
     CDS             complement(9985..10809)
                     /locus_tag="ROH59_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDX4802739.1"
                     /translation="MIIEKVMNNNCVQASMNGQEVIISGPGVGYNKKYGMSVPEHPAN
                     RIFYVRNEQKNKLYKLIEHVDIEYVFVAEKIVQYAEKNLEKNLNPSLLLILADHISNA
                     ISRVASGIQINNVFLDEIKALYKAEYAISRDALTIINEQFSVQLPDDEIGFIALHILN
                     NYENSVDYESVRIIELSQIITGLIEVVYNRKVDRSSFNYSRFMMHLKYFSSRVLCNEE
                     IKQKDIGDIYEQFLEKDILLQRAIHEIERYLYATFKYELILEEKLYLSIRTKVLMD"
     gene            complement(11067..12320)
                     /gene="amiC"
                     /locus_tag="ROH59_000197"
     CDS             complement(11067..12320)
                     /gene="amiC"
                     /locus_tag="ROH59_000197"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HDX4802740.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATLARRG"
     gene            12552..13883
                     /gene="argA"
                     /locus_tag="ROH59_000198"
     CDS             12552..13883
                     /gene="argA"
                     /locus_tag="ROH59_000198"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HDX4802741.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQTRVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(13965..15791)
                     /gene="recD"
                     /locus_tag="ROH59_000199"
     CDS             complement(13965..15791)
                     /gene="recD"
                     /locus_tag="ROH59_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HDX4802742.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTAEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERAGQLSRLTG
                     SHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTD
                     IEKRLLQSGEDYIAMLEEVLAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRG"
     gene            complement(15791..19333)
                     /gene="recB"
                     /locus_tag="ROH59_000200"
     CDS             complement(15791..19333)
                     /gene="recB"
                     /locus_tag="ROH59_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HDX4802743.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYKRLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIDAVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIEKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGEMQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDAVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDVAGLRTC
                     IEALCDDDIAWQTAQIGDNQPWQVNDALTAELNARTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVVSVVEVPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VQEKLELGGFEPQWEPVLTEWITAVLLAPLNETGISLSQLSDRDKQVEMEFYLPISEP
                     LIASQLDALIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYERHFGGVIYLFLRGV
                     DKEHPQQGIYATRPNAGLIDLMDEMFAGMTLEEA"
     gene            complement(19326..22214)
                     /gene="ptrA"
                     /locus_tag="ROH59_000201"
     CDS             complement(19326..22214)
                     /gene="ptrA"
                     /locus_tag="ROH59_000201"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HDX4802744.1"
                     /translation="MPRSIWFKALLLFVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAANIALSLPELNPYIP
                     DDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEAQAITLARHVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPEEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKIADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(22390..25758)
                     /gene="recC"
                     /locus_tag="ROH59_000202"
     CDS             complement(22390..25758)
                     /gene="recC"
                     /locus_tag="ROH59_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HDX4802745.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLPQL
                     LEREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTDELGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVTPDNL
                     LHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(25771..26094)
                     /locus_tag="ROH59_000203"
     CDS             complement(25771..26094)
                     /locus_tag="ROH59_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDX4802746.1"
                     /translation="MSASLRNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLASR
                     NQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(26079..26486)
                     /locus_tag="ROH59_000204"
     CDS             complement(26079..26486)
                     /locus_tag="ROH59_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311708.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HDX4802747.1"
                     /translation="MNREKGVSSLALVLMLLILGSLLLQGMSQQDRSFASRVSMESQS
                     LRRQAIVQSALEWGKMHSWQTLPAVQCLLYAATGARVCLRLLADNEALLIAGYEGVSL
                     WRTGEVIDGNIVFSPRGWSDFCPLKERALCQLP"
     gene            complement(26483..27046)
                     /locus_tag="ROH59_000205"
     CDS             complement(26483..27046)
                     /locus_tag="ROH59_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDX4802748.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTNTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGSCTGEGLEIVGQGDCVIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGATSCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
                     TVNMHAASKADPQTVVDASYSVTGSNL"
     gene            complement(27037..27507)
                     /locus_tag="ROH59_000206"
     CDS             complement(27037..27507)
                     /locus_tag="ROH59_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDX4802749.1"
                     /translation="MKKQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISLIREGTLWCLVSSVAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(27692..28486)
                     /gene="thyA"
                     /locus_tag="ROH59_000207"
     CDS             complement(27692..28486)
                     /gene="thyA"
                     /locus_tag="ROH59_000207"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDX4802750.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(28493..29368)
                     /gene="lgt"
                     /locus_tag="ROH59_000208"
     CDS             complement(28493..29368)
                     /gene="lgt"
                     /locus_tag="ROH59_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDX4802751.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(29519..31765)
                     /gene="ptsP"
                     /locus_tag="ROH59_000209"
     CDS             complement(29519..31765)
                     /gene="ptsP"
                     /locus_tag="ROH59_000209"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDX4802752.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRRIDFAEAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(31778..32308)
                     /gene="rppH"
                     /locus_tag="ROH59_000210"
     CDS             complement(31778..32308)
                     /gene="rppH"
                     /locus_tag="ROH59_000210"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HDX4802753.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            32993..33682
                     /gene="mutH"
                     /locus_tag="ROH59_000211"
     CDS             32993..33682
                     /gene="mutH"
                     /locus_tag="ROH59_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HDX4802754.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAKRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDMIVLGQIERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLARHFLIQ"
     gene            33751..34464
                     /locus_tag="ROH59_000212"
     CDS             33751..34464
                     /locus_tag="ROH59_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDX4802755.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            34602..34820
                     /gene="ygdR"
                     /locus_tag="ROH59_000213"
     CDS             34602..34820
                     /gene="ygdR"
                     /locus_tag="ROH59_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HDX4802756.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            34928..35968
                     /locus_tag="ROH59_000214"
     CDS             34928..35968
                     /locus_tag="ROH59_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HDX4802757.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHSLDPAQMALAFVRRQPFVASTLLGATTMEQLKTNVESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(36000..37193)
                     /gene="lplT"
                     /locus_tag="ROH59_000215"
     CDS             complement(36000..37193)
                     /gene="lplT"
                     /locus_tag="ROH59_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HDX4802758.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLIALAACALAYGGAVIANIYIPKLAAARPGQSWNLISMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(37186..39345)
                     /gene="aas"
                     /locus_tag="ROH59_000216"
     CDS             complement(37186..39345)
                     /gene="aas"
                     /locus_tag="ROH59_000216"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HDX4802759.1"
                     /translation="MLFSFFRNLCRVLYRVRVTGDTKALKGERVLITPNHVSFIDGIL
                     LALFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAI
                     ARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQLKQQPEEEALILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENIRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            39931..40962
                     /gene="galR"
                     /locus_tag="ROH59_000217"
     CDS             39931..40962
                     /gene="galR"
                     /locus_tag="ROH59_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HDX4802760.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETIGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIPANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(40969..42231)
                     /gene="lysA"
                     /locus_tag="ROH59_000218"
     CDS             complement(40969..42231)
                     /gene="lysA"
                     /locus_tag="ROH59_000218"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDX4802761.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVLEFGQD
                     LQAISAGGGLSIPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     AGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            42353..43288
                     /gene="lysR"
                     /locus_tag="ROH59_000219"
     CDS             42353..43288
                     /gene="lysR"
                     /locus_tag="ROH59_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HDX4802762.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERIRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAVKKVLTPDDFHGENYISLSRTDSYRQLLDQLFTENQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(43275..43967)
                     /gene="ygeA"
                     /locus_tag="ROH59_000220"
     CDS             complement(43275..43967)
                     /gene="ygeA"
                     /locus_tag="ROH59_000220"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDX4802763.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCSLPFL
                     HIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADDRAKINQI
                     IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(44096..45514)
                     /gene="araE"
                     /locus_tag="ROH59_000221"
     CDS             complement(44096..45514)
                     /gene="araE"
                     /locus_tag="ROH59_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HDX4802764.1"
                     /translation="MVTINTESALTPRPLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
     gene            complement(45829..46590)
                     /gene="kduD"
                     /locus_tag="ROH59_000222"
     CDS             complement(45829..46590)
                     /gene="kduD"
                     /locus_tag="ROH59_000222"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HDX4802765.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIKQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPVVFLASSASDYVNGYTIAVDGGWLAR"
     gene            complement(46620..47456)
                     /gene="kduI"
                     /locus_tag="ROH59_000223"
     CDS             complement(46620..47456)
                     /gene="kduI"
                     /locus_tag="ROH59_000223"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HDX4802766.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDR
                     IIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRD
                     ALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            complement(47743..48924)
                     /locus_tag="ROH59_000224"
     CDS             complement(47743..48924)
                     /locus_tag="ROH59_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDX4802767.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVP
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVITQSNGQTLVVDTDEQ
                     PRTDTSAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
     gene            49179..50408
                     /locus_tag="ROH59_000225"
     CDS             49179..50408
                     /locus_tag="ROH59_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HDX4802768.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGN
                     LITLIVGILCVSVMFFS"
     gene            complement(50725..50798)
                     /locus_tag="ROH59_000226"
     tRNA            complement(50725..50798)
                     /locus_tag="ROH59_000226"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50764..50766),aa:Gly,seq:ccc)
     gene            complement(50877..51632)
                     /locus_tag="ROH59_000227"
     CDS             complement(50877..51632)
                     /locus_tag="ROH59_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311765.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDX4802769.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSSTRKSTAKSTT
                     KTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYA
                     AGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGST
                     DAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            52046..54343
                     /gene="xdhA"
                     /locus_tag="ROH59_000228"
     CDS             52046..54343
                     /gene="xdhA"
                     /locus_tag="ROH59_000228"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HDX4802770.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPEIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAVQLVSIEWQELPVITSSEAALAEDAAPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALDIPWSCVRVIKPFIGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            54354..55232
                     /gene="xdhB"
                     /locus_tag="ROH59_000229"
     CDS             54354..55232
                     /gene="xdhB"
                     /locus_tag="ROH59_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HDX4802771.1"
                     /translation="MFDFASYHRAATLADAINLLTDNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGALRIGSATTFTQLIEDPVTQRHLPALCAAAASIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            55229..55708
                     /gene="xdhC"
                     /locus_tag="ROH59_000230"
     CDS             55229..55708
                     /gene="xdhC"
                     /locus_tag="ROH59_000230"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HDX4802772.1"
                     /translation="MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLFLAAWAEGKEIRTLEGEAKGGKLSHVQLAYAKSGAVQ
                     CGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK"
     gene            complement(55747..57525)
                     /locus_tag="ROH59_000231"
     CDS             complement(55747..57525)
                     /locus_tag="ROH59_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HDX4802773.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAG
                     TGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTP
                     VILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
                     IFATMIDNMDQGVLVVDADNRVQFVNQTALKTLGVVQNNIIGKPVRFRPLTFESNFTH
                     GHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGEC
                     RVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPE
                     QLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAR
                     EILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQED
                     IELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGE
                     VIDSTLLPPNLLNNGTTEQSDVTEASEAHLSLDDAGGTALEEMEKQMIREALSRHNSK
                     KEVADELGIGIATLYRKIKKYELLNT"
     gene            58004..59191
                     /gene="ygeW"
                     /locus_tag="ROH59_000232"
     CDS             58004..59191
                     /gene="ygeW"
                     /locus_tag="ROH59_000232"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HDX4802774.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
     gene            59249..60445
                     /gene="dpaL"
                     /locus_tag="ROH59_000233"
     CDS             59249..60445
                     /gene="dpaL"
                     /locus_tag="ROH59_000233"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDX4802775.1"
                     /translation="MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEG
                     KHAVAP"
     gene            60503..61714
                     /locus_tag="ROH59_000234"
     CDS             60503..61714
                     /locus_tag="ROH59_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDX4802776.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            61767..63152
                     /gene="hyuA"
                     /locus_tag="ROH59_000235"
     CDS             61767..63152
                     /gene="hyuA"
                     /locus_tag="ROH59_000235"
                     /EC_number="3.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HDX4802777.1"
                     /translation="MRVLIKNGIVVNADGQAKQDLLIESGIVRQLGTDISPQLPCEEI
                     DASGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRISPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            63200..64132
                     /gene="arcC"
                     /locus_tag="ROH59_000236"
     CDS             63200..64132
                     /gene="arcC"
                     /locus_tag="ROH59_000236"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDX4802778.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAELLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(64173..65798)
                     /locus_tag="ROH59_000237"
     CDS             complement(64173..65798)
                     /locus_tag="ROH59_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDX4802779.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLHQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMVDPTCSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFT
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(65846..66616)
                     /gene="yqeC"
                     /locus_tag="ROH59_000238"
     CDS             complement(65846..66616)
                     /gene="yqeC"
                     /locus_tag="ROH59_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDX4802780.1"
                     /translation="MKSIIDPSALFIDLGAQKRPTVISIVGAGGKTSLLFWLAELFQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASFISPISFCFHCWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHILGAKV
                     STENVHRWSQFADITGLTPDAPLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHNVEAIWLGDIQEHPAIARRFVN"
     gene            66720..67298
                     /gene="mocA"
                     /locus_tag="ROH59_000239"
     CDS             66720..67298
                     /gene="mocA"
                     /locus_tag="ROH59_000239"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDX4802781.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVQTEHCFLTHGDM
                     PTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNVTNMRQALLMG
                     EHYSVEIENAEIILDIDTPDDFITAKKRYTEI"
     gene            67620..70718
                     /gene="ygfK"
                     /locus_tag="ROH59_000240"
     CDS             67620..70718
                     /gene="ygfK"
                     /locus_tag="ROH59_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HDX4802782.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKSKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDALNKLLQDEAFLARHGLQEKRESLQALPARIPTS
                     MVQGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWELNHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPD
                     LTVEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATVVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLHVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDTILSRENIRSH
                     QNDKYWNNVNPAEIYQRKGDISVTLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLSQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLGRV
                     EV"
     gene            70721..72049
                     /gene="ssnA"
                     /locus_tag="ROH59_000241"
     CDS             70721..72049
                     /gene="ssnA"
                     /locus_tag="ROH59_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDX4802783.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIDGSLSTLRNAFLKVGLRAMTCFETTDRN
                     NGIKELQEGVEENIRFTRQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLREAVK
                     STGRGLHIHVAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDIVLL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALANGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            72100..72879
                     /locus_tag="ROH59_000242"
     CDS             72100..72879
                     /locus_tag="ROH59_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HDX4802784.1"
                     /translation="MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWIDWDNGALRIGAMSRLQPLRDARFIPAALREALGFVYSRHVRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVAITDHDGMRIALDGVASKALRLHDVETQNLEGNALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            72876..75746
                     /locus_tag="ROH59_000243"
     CDS             72876..75746
                     /locus_tag="ROH59_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HDX4802785.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIDAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEDIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFHGAQILGEPVADVQLATPGVVRGKKGEVSFGEIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            75911..77311
                     /gene="xanQ"
                     /locus_tag="ROH59_000244"
     CDS             75911..77311
                     /gene="xanQ"
                     /locus_tag="ROH59_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HDX4802786.1"
                     /translation="MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGLGISYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGY
                     RQENVLPGITSAEEMD"
     gene            77329..78645
                     /gene="guaD"
                     /locus_tag="ROH59_000245"
     CDS             77329..78645
                     /gene="guaD"
                     /locus_tag="ROH59_000245"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HDX4802787.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTVDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWEDGKHQIPDTIRVRDYRGKLIVPGFIDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
     gene            78681..80048
                     /gene="ghxQ"
                     /locus_tag="ROH59_000246"
                     /gene_synonym="ygfQ"
     CDS             78681..80048
                     /gene="ghxQ"
                     /locus_tag="ROH59_000246"
                     /gene_synonym="ygfQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxQ"
                     /protein_id="HDX4802788.1"
                     /translation="MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGVLFLMILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(80084..80572)
                     /locus_tag="ROH59_000247"
     CDS             complement(80084..80572)
                     /locus_tag="ROH59_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDX4802789.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADIFLPRLKVQ
                     RLDSISAPVMCHQCENAPCVGACPVGALTMGEQVVQANSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASSEN
                     PL"
     gene            complement(80572..82491)
                     /gene="ygfT"
                     /locus_tag="ROH59_000248"
     CDS             complement(80572..82491)
                     /gene="ygfT"
                     /locus_tag="ROH59_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HDX4802790.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIDVCPTQALRLMDDKGLQQIKVARQRKTAAGKASS
                     DAQPSRSAALLPVNSRKGADKISASERKTHFGEIYCGLDPQQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCADILARAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDISFNEL
                     TAEYDAVFLGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESAEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNAREEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHTMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAS"
     gene            82927..84375
                     /gene="uacT"
                     /locus_tag="ROH59_000249"
     CDS             82927..84375
                     /gene="uacT"
                     /locus_tag="ROH59_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate/proton symporter UacT"
                     /protein_id="HDX4802791.1"
                     /translation="MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAG
                     AVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFA
                     AVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
                     SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFG
                     FLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFL
                     ALGEIVGRKLSSQDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVC
                     ISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYN
                     LYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHAD
                     LVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE"
     gene            84377..84502
                     /locus_tag="ROH59_000250"
     CDS             84377..84502
                     /locus_tag="ROH59_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802792.1"
                     /translation="MNLLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF"
     gene            complement(84499..84570)
                     /locus_tag="ROH59_000251"
     CDS             complement(84499..84570)
                     /locus_tag="ROH59_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802793.1"
                     /translation="MINQVSVYRQPPVLSGCRQVKTI"
     gene            84625..85173
                     /gene="idi"
                     /locus_tag="ROH59_000252"
     CDS             84625..85173
                     /gene="idi"
                     /locus_tag="ROH59_000252"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDX4802794.1"
                     /translation="MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKG
                     QLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEEAVIRRCRYELGVEITPPESIYPDF
                     RYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLAAVLRGIDATPWAFSP
                     WMVMQATNREARKRLSAFTQLK"
     gene            complement(85216..86733)
                     /gene="lysS"
                     /locus_tag="ROH59_000253"
     CDS             complement(85216..86733)
                     /gene="lysS"
                     /locus_tag="ROH59_000253"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDX4802795.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(86743..87841)
                     /gene="prfB"
                     /locus_tag="ROH59_000254"
     CDS             complement(join(86743..87765,87767..87841))
                     /gene="prfB"
                     /locus_tag="ROH59_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDX4802796.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            complement(87932..89665)
                     /gene="recJ"
                     /locus_tag="ROH59_000255"
     CDS             complement(87932..89665)
                     /gene="recJ"
                     /locus_tag="ROH59_000255"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDX4802797.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTD
                     HHLPGDTLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDPQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEEKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            complement(89671..90381)
                     /gene="dsbC"
                     /locus_tag="ROH59_000256"
     CDS             complement(89671..90381)
                     /gene="dsbC"
                     /locus_tag="ROH59_000256"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HDX4802798.1"
                     /translation="MKKGFMLFTLLAAFSGFVQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIW
                     CAKDKNKAFDDVMAGKSVAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQP
                     PKDMKEFLDEHQKMTSGK"
     gene            complement(90406..91302)
                     /gene="xerD"
                     /locus_tag="ROH59_000257"
     CDS             complement(90406..91302)
                     /gene="xerD"
                     /locus_tag="ROH59_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDX4802799.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            91414..91935
                     /gene="fldB"
                     /locus_tag="ROH59_000258"
     CDS             91414..91935
                     /gene="fldB"
                     /locus_tag="ROH59_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HDX4802800.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     MLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
                     CEQILNEMAEHYA"
     gene            complement(91975..92382)
                     /locus_tag="ROH59_000259"
     CDS             complement(91975..92382)
                     /locus_tag="ROH59_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HDX4802801.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLIPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWSIVKAPWMIKSGMMLRLRSD
                     SGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(92363..92629)
                     /gene="sdhE"
                     /locus_tag="ROH59_000260"
     CDS             complement(92363..92629)
                     /gene="sdhE"
                     /locus_tag="ROH59_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HDX4802802.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRTFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            92872..93852
                     /gene="ygfZ"
                     /locus_tag="ROH59_000261"
     CDS             92872..93852
                     /gene="ygfZ"
                     /locus_tag="ROH59_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HDX4802803.1"
                     /translation="MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQ
                     VTADVSQMTEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARTALANLFSELPSREKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLTGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLRIEPLPYSLEE"
     gene            complement(93929..94588)
                     /locus_tag="ROH59_000262"
     CDS             complement(93929..94588)
                     /locus_tag="ROH59_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDX4802804.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     VKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     V"
     gene            complement(94752..95063)
                     /locus_tag="ROH59_000263"
     CDS             complement(94752..95063)
                     /locus_tag="ROH59_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDX4802805.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELKKVIADIYPDQTQFYVIEFKC
                     L"
     gene            95108..96541
                     /gene="bglA"
                     /locus_tag="ROH59_000264"
     CDS             95108..96541
                     /gene="bglA"
                     /locus_tag="ROH59_000264"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HDX4802806.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHG
                     VPREITKEVVPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMIDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASALAVKAAHRINPEMKVGCMLAMVPLYPYSCNPDDVMFAQKSMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKVEDDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GTGDMSRSRKKSFNWYKEVIASNGENL"
     gene            complement(96707..99580)
                     /gene="gcvP"
                     /locus_tag="ROH59_000265"
     CDS             complement(96707..99580)
                     /gene="gcvP"
                     /locus_tag="ROH59_000265"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HDX4802807.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGALLQ
                     QVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDID
                     TLDKDVAHDSRSIQAAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLAEWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLIRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            complement(99699..100088)
                     /gene="gcvH"
                     /locus_tag="ROH59_000266"
     CDS             complement(99699..100088)
                     /gene="gcvH"
                     /locus_tag="ROH59_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDX4802808.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            complement(100112..101206)
                     /gene="gcvT"
                     /locus_tag="ROH59_000267"
     CDS             complement(100112..101206)
                     /gene="gcvT"
                     /locus_tag="ROH59_000267"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HDX4802809.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            101497..101580
                     /locus_tag="ROH59_000268"
     CDS             101497..101580
                     /locus_tag="ROH59_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802810.1"
                     /translation="MSKNTKSKIRGIRKYNAKSQVKLVYFK"
     gene            complement(101654..102856)
                     /gene="ubiI"
                     /locus_tag="ROH59_000269"
                     /gene_synonym="visC"
     CDS             complement(101654..102856)
                     /gene="ubiI"
                     /locus_tag="ROH59_000269"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HDX4802811.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGIGLRVAVLEQRVPEPLAADA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRACCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWNKALQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQAGEDEFNRALNIAFDNRLGLCKVESERLVFPLTGRYA
                     RQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSAALMLAGMQGFRDLFSGANPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(102879..104057)
                     /gene="ubiH"
                     /locus_tag="ROH59_000270"
                     /gene_synonym="visB"
     CDS             complement(102879..104057)
                     /gene="ubiH"
                     /locus_tag="ROH59_000270"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HDX4802812.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLESGETLTGRVLVA
                     ADGTHSALATACGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQYGPLAMLPMSDG
                     RCSLVWCHPLERREEVLSWSDEKFCRELQSAFGWRLGQITHAGKRSAYPLALTRAAKP
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAQERREDMGDYGVLCRYQQ
                     RRQRDREATIGVTDSLVHLFANRWTPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
                     "
     gene            complement(104054..105379)
                     /gene="pepP"
                     /locus_tag="ROH59_000271"
     CDS             complement(104054..105379)
                     /gene="pepP"
                     /locus_tag="ROH59_000271"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HDX4802813.1"
                     /translation="MSDISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADEIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITALAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENECELRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSIQEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     AEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ"
     gene            complement(105405..105983)
                     /gene="ygfB"
                     /locus_tag="ROH59_000272"
     CDS             complement(105405..105983)
                     /gene="ygfB"
                     /locus_tag="ROH59_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HDX4802814.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            106151..106480
                     /gene="zapA"
                     /locus_tag="ROH59_000273"
     CDS             106151..106480
                     /gene="zapA"
                     /locus_tag="ROH59_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDX4802815.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            106522..106705
                     /gene="ssrS"
                     /locus_tag="ROH59_000274"
     ncRNA           106522..106705
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ROH59_000274"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            106726..107328
                     /locus_tag="ROH59_000275"
     CDS             106726..107328
                     /locus_tag="ROH59_000275"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDX4802816.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNKLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKMQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(107429..107488)
                     /gene="ibsC"
                     /locus_tag="ROH59_000276"
     CDS             complement(107429..107488)
                     /gene="ibsC"
                     /locus_tag="ROH59_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HDX4802817.1"
                     /translation="MMRLVIILIVLLLISFSAY"
     gene            complement(107717..108949)
                     /gene="serA"
                     /locus_tag="ROH59_000277"
     CDS             complement(107717..108949)
                     /gene="serA"
                     /locus_tag="ROH59_000277"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDX4802818.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            complement(109205..109864)
                     /gene="rpiA"
                     /locus_tag="ROH59_000278"
     CDS             complement(109205..109864)
                     /gene="rpiA"
                     /locus_tag="ROH59_000278"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDX4802819.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            complement(109920..110150)
                     /locus_tag="ROH59_000279"
     CDS             complement(109920..110150)
                     /locus_tag="ROH59_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802820.1"
                     /translation="MHFAQRVRALVVLNGVALLPQFACKQGLANGELVRLFAPWSGIP
                     RPLYALFAGRKGMPAIARYFMDELTTRLANGV"
     gene            110291..111184
                     /gene="argP"
                     /locus_tag="ROH59_000280"
     CDS             110291..111184
                     /gene="argP"
                     /locus_tag="ROH59_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HDX4802821.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            111387..112442
                     /locus_tag="ROH59_000281"
     CDS             111387..112442
                     /locus_tag="ROH59_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HDX4802822.1"
                     /translation="MSNVQEWQQLANKELSRREKTVDSLVQQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLATHRGYD
                     SDNPRVAGDVGKAGVAIDTVEDIKVLFDQIPLDKMSVSMTMNGAVLPVLAFYIVAAEE
                     QGVTSDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCSGNMPRFNTISISG
                     YHMGEAGANCVQQVAFTLADRIEYIKAAISAGLKIDDFAPRLSFFFGIGMDLFMNVAM
                     LRAARYLWSEAVSGFGAQDPYNNVIRTTIDHCAHPMYRDYLHRYLENASGGHIHHDLS
                     HVFDLHRNLIATGSMLG"
     gene            complement(112439..113335)
                     /locus_tag="ROH59_000282"
                     /pseudo
     CDS             complement(112439..113335)
                     /locus_tag="ROH59_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(113503..114243)
                     /locus_tag="ROH59_000283"
     CDS             complement(113503..114243)
                     /locus_tag="ROH59_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HDX4802823.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFNRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            complement(114336..114971)
                     /gene="argO"
                     /locus_tag="ROH59_000284"
     CDS             complement(114336..114971)
                     /gene="argO"
                     /locus_tag="ROH59_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HDX4802824.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAE
                     VLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            complement(115110..115970)
                     /gene="mscS"
                     /locus_tag="ROH59_000285"
     CDS             complement(115110..115970)
                     /gene="mscS"
                     /locus_tag="ROH59_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HDX4802825.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPARRNEFIIGVAYDSDIDQVKQILTDIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            complement(116161..117240)
                     /gene="fbaA"
                     /locus_tag="ROH59_000286"
     CDS             complement(116161..117240)
                     /gene="fbaA"
                     /locus_tag="ROH59_000286"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HDX4802826.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            complement(117454..118617)
                     /gene="pgk"
                     /locus_tag="ROH59_000287"
     CDS             complement(117454..118617)
                     /gene="pgk"
                     /locus_tag="ROH59_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDX4802827.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            complement(118667..119686)
                     /gene="epd"
                     /locus_tag="ROH59_000288"
     CDS             complement(118667..119686)
                     /gene="epd"
                     /locus_tag="ROH59_000288"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HDX4802828.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            120058..120489
                     /locus_tag="ROH59_000289"
     CDS             120058..120489
                     /locus_tag="ROH59_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDX4802829.1"
                     /translation="MMTLPYPYSSSARFYALRLLPGQEVLSQLRAFAQQQQLHAAWIA
                     GCTGSLTDVALRYAGQENTALLSGKFEVIALNGTLEQSGEHLHLCVSDPHGTMLGGHM
                     MPGCTVRTTLELVIGCLEELAFSRQLCALSGYDELHISPVK"
     gene            120512..121090
                     /locus_tag="ROH59_000290"
     CDS             120512..121090
                     /locus_tag="ROH59_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDX4802830.1"
                     /translation="MARRHFSSQALVLIVISIAINMIGGQLASMVKLPIFLDSIGTLI
                     SAVLLGPIIGMLTGLLTNLLWGLLTDPIAAAFAPVAMVIGLVAGWLARAGWFRTLPKV
                     VVSGVIITLAVTVVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
                     VDKILTAVIVWLLLRQLPIRTTRHFPAMAAVR"
     gene            121091..121798
                     /locus_tag="ROH59_000291"
     CDS             121091..121798
                     /locus_tag="ROH59_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDX4802831.1"
                     /translation="MHPFTSLTLWALAACTTLILPTQTILPVYSAATFFCLIALKATR
                     RRAKYVVWLMFSLGAGLWLVHGGWLTEWLSGTPHSPERWAHAITLWLRILAIVSTSQL
                     WMQYVPVQRFIRALFASRLPPGVAYLFAGPLLVVEQLKRQLAIIHEAQCARGVPLDEG
                     WYQRLRAMPALIIPLTHNALNDLAVRGAALDMRAFRINNRRTTLWAPADSTLQCVARY
                     AMILLMLAEFGAWIWLR"
     gene            121786..122463
                     /locus_tag="ROH59_000292"
     CDS             121786..122463
                     /locus_tag="ROH59_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDX4802832.1"
                     /translation="MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTL
                     AQLMAGWYPDFLPGEITGTGTLLGTPIGRLPLNEQSATIQLVQQSPYLQLSGCTFSVE
                     EEVAFGPENLCLAEKEIMARIDAALALTECQPLRHRHPATLSGGETQRVVIACAIAMQ
                     PKLLILDEAFSRLTPQAREMLLQRLQHWALERGSLIILFERHHTPFLNHCQQAWQLQN
                     GALQPLC"
     gene            122457..123134
                     /locus_tag="ROH59_000293"
     CDS             122457..123134
                     /locus_tag="ROH59_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDX4802833.1"
                     /translation="MLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKST
                     LLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKIGVLFQEAENQLFHSTVADEIAFG
                     LILQKCPADEITQRTNAALQCCQLADTASAHPLDLHSAQRRMVAVACLEALSPPLLLL
                     DEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVN
                     PSDDIHP"
     gene            complement(123106..123819)
                     /locus_tag="ROH59_000294"
     CDS             complement(123106..123819)
                     /locus_tag="ROH59_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HDX4802834.1"
                     /translation="MKIELTVNGLKVQAQYSDDEIENVHKPLLRMLAALQTVNPQRRT
                     VVFLCAPPGTGKSTLTTFWEYLAQQDPELPAIQTLPMDGFHHYNSWLDVHQLRPFKGA
                     PETFNVAKLAENLCRVVEGDCTWPQYDRQKHDPVEDVLHVTAPLVIVEGNWLLLDDEK
                     WCQLAQFCDFSIFIKAPASALRERLVGRKLAGGLSLADAEAFYDRTDGPNVRRVLEES
                     LPANLTLMMTATGEYRLMD"
     gene            complement(123816..124325)
                     /gene="fumE"
                     /locus_tag="ROH59_000295"
     CDS             complement(123816..124325)
                     /gene="fumE"
                     /locus_tag="ROH59_000295"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HDX4802835.1"
                     /translation="MATLTEDDVLEQLNAQDNLFSFMKTAHSILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQD
                     ETPRFADDITWDFISNVNSITRNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            complement(124347..125312)
                     /gene="yggF"
                     /locus_tag="ROH59_000296"
     CDS             complement(124347..125312)
                     /gene="yggF"
                     /locus_tag="ROH59_000296"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDX4802836.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAV
                     MAFAPRDSLLHAPDMYMKKLVVNRLAAGAIDLSLPLADNLRNVARALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAELIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            complement(125309..126586)
                     /locus_tag="ROH59_000297"
     CDS             complement(125309..126586)
                     /locus_tag="ROH59_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDX4802837.1"
                     /translation="MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVVVEVGKNLTGKYKKGQRFVLQPAMGLPSG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPARVVVVDIDDKRLAQV
                     QKLLPVELAASKGIELVYMNTKGMSDPVQTLRALTDDAGFDDVFVYAAVPSVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHIVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEKTHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            complement(126601..127989)
                     /gene="cmtA"
                     /locus_tag="ROH59_000298"
     CDS             complement(126601..127989)
                     /gene="cmtA"
                     /locus_tag="ROH59_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDX4802838.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYIDKSLEKRIPAGFEMVINNFSLGIAGMLFCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETKSEDEFTESANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            complement(128017..128460)
                     /gene="cmtB"
                     /locus_tag="ROH59_000299"
     CDS             complement(128017..128460)
                     /gene="cmtB"
                     /locus_tag="ROH59_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HDX4802839.1"
                     /translation="MRLIDYFPESSISVIHSAKDWQEAIDFSMASLLDKNYISENYIQ
                     SIKDSTISNGPYYILAPGVAMPHARPECGALKTGMSLTLLKQGVYFPGKDEPIKLLIG
                     LSAADANSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG"
BASE COUNT        31945 a        34045 c        31419 g        31137 t
ORIGIN      
        1 tttattgaag aaatcctcat ctagtatgga gtccgatttt tcttttgaaa taaatgatcc
       61 atctatatgt ccttaggatt ctgaaaataa aaaattctaa tctcactact cgttggtatt
      121 aatttcaata aaaggaaaga taaatcctcc gatggacgac ctgacccaac gctactttga
      181 ggccgaaatg cgctacctgc gtgaagcggg gaaagaattt gcgcaggctt accccgaccg
      241 cgctgcgatg cttaatcttg ataaacccgg cgcacgcgat ccctatgtgg agcgcctgtt
      301 cgagggcttc gcttttttaa tgggccgcct gcgcgaaaag ctggacgacg atctgccgga
      361 actgactgaa gggctggtca gcctgctgtg gccgcactac ctgcgcacta ttccgtcgct
      421 ttccgtggtc gaactgacca cggatcacca acaaatgaag caaagtgata cgctgaaaga
      481 gtttcaggtg ctatcccgtc ccatcggcga acgcagaacc cgctgcgtct acagcgccac
      541 gcgggatatc acgctgcatc cgctggcgtt gccggacgtg tcattgcaat atgaaccgga
      601 cggacgctcg gttatccgtc tgcgctttga atgcggcccg ctggttggtg actggtcaca
      661 gattgattta tcccgcctgc cgctgtacct cagtgccgac agcccggtgg cctgtgcgct
      721 gcaccgggct ttaacgcttg gtacgcagca gttctggctg cgtctgccag ggcagggacg
      781 ccgtgtgctg gacgcgcact tttccccgat gggttttgat gacgatgacc gactgtggcc
      841 gaaaggcgaa tcggcgttca gcggctacca gttgctgctg gagtatttca ccttccgcga
      901 gaagtttatg ttcgtggcgc tgaacgggct ggagcaggtt gcatggccgg aggggataac
      961 cggctttgag attgacgtgt tgctgaacga gaactggcct cacgacctgc cgtttgacag
     1021 cgataatatc cgtctgcact gcgtgccggt catcaacctg tttccgctgg aagccgatcc
     1081 gttacacctt tcgccactgg aaaacgaatt tctgctgcgc ccgatgcgca ttcaggacgg
     1141 gcataccgag atttattccg tcgacaacat tatttcttcg cgccataccg gcagtcaggc
     1201 gtatgtgcca ttctccagct ttcgtcaccg gggcgggatg ctgcgccacg atgcgccgga
     1261 acgctattac cacacgcggg taaagcgcgg cccttccggc ctgcatgaca cctggctgat
     1321 tctgggcggc gatgcgtttg atactgaccg gatgctggag gatgaaaccc tgtccttaag
     1381 cctgaccggt actaacgggc agcttccccg taaagcttta cagagcacgc tgctcgatac
     1441 gccagttcat gcctcacaga acgtcctgcg ggtgcgcaac ctgtgcgccc cgacgcagcc
     1501 ctgctatccc ccggcgcgtg accgcttcca ctggcgggtg ctcagccacc ttggttctaa
     1561 ctttttatcg atgatggata acgccgaaat tctgcgcggc acgctggcgc tgtacgactg
     1621 gaccgaaagc gagatgaacc gccgtcgtct ggcggcgatt gtcgacgttc agcacagcct
     1681 gatacagcgt tttgaaagag gctttctgct gcgtggcgtg gatattcagg tgacgctgga
     1741 cagtaacggc tttgccggag aaggtgatat cacgctgttt ggtgaactgc tgcaccgctt
     1801 cttcgcactg tatgccgata tccacttatt cactcaacta accttaattc tgcaacccac
     1861 aggaaagtgc ctgcaatgga cagagcatca cagccagcgc gtaccgggct gaccgaccgg
     1921 ctggccccgg atattgcgcg gatcaatttt taccgttttt gccagttgct ggaacagcgc
     1981 cagcagaacg cgccgctggg cagtaccgac agccccgccg ccgatgcggt gcgctttcgt
     2041 cctcatccgg ggatgggctt tccggtcagc gagttaaaga acgttgaacg tgacgtggac
     2101 aatcccgacg cgccacccac agtgcgcacc acttttctcg gcctgtacgg cgtggattcg
     2161 ccactgccaa ccgcctatct ggactacatt acccagcgtc atgacggaca tgacgcggtg
     2221 atggcgtttc tcgatatttt taaccatcgc tttatcaccc agtattaccg catctggcgc
     2281 aaatataact acccggcgtc gtttgaagca ggtgcagtgg atgacatttc ccgttgcctg
     2341 ctgggactca tcgggctggg tattcccggc agcgagaacc atatcgccac gccggtatcc
     2401 cgttttctgg ccctgctcag cgtgatgcgc ctgccgacgc gcacggcgga aggcgttacg
     2461 gcactggtgg gactgcttgc cccgctgacg aaagcgacgg tggtgcctca tgatccgcag
     2521 cctgtaattc tcccggcccc tgcgggtctg tcaaaaaatt cacccatcag cctgaaaacg
     2581 cgaacgctgc tggggcgtac cggcaccgac gtcaacagcc agttgctgct gaaactgtat
     2641 accgaagatg ccgcagaagc acgtggctgg ctgcccggcg ggcaactgca cagcgatttg
     2701 ctggtgctgc tgcgcgttta tctgggctgg cgctgtcagg cccgactgca actgacgctg
     2761 cccgtcagcc tgttgcctgc tgcccggctg ggaaaacagc gtgtacagat tagccgtacc
     2821 ggcatccttc gcgcctcctt tgccgcgccc gcgaccggaa cagtgacggt cagtctgggg
     2881 cgttatcagg gattaatacc cgctttttcc attcgtaaca gggagagtat gactcatgtt
     2941 tcctattcgt tttaaacgtc cggcgctgct ctgtatggcg atgctgacgg ttgttctgag
     3001 cggctgcggg ctgattcaga aagtggtgga tgaatcgaaa agcgtggcct cagccgtttt
     3061 ctacaagcaa atcaaaatac tgcatctcga tttcttctcc cgaagtgccc tgaatacgga
     3121 tgcggaagat acgccgcttt ccacgatggt gcatgtctgg caactgaaaa cccgcgaaga
     3181 ttttgacaag gcggattatg acaccctgtt tatgcaggaa gagaagacgc tggagaagaa
     3241 cgtactggca aaacacaccg tctgggtaaa accggaaggc acggcatccc tgaatgtgcc
     3301 gctggataaa gagacgcagt ttgtcgccat tattgggcag ttttatcacc ctgatgaaaa
     3361 aagcgacagc tggcgtctgg tgatcaaaag ggacgaactg gaggccgaca agccgcgctc
     3421 gattgaactg atgagaagcg acctgcgact gctgcctctc aaggataaat aaccgatgtc
     3481 gacaccttcc ttatatgaaa tgctgacgtt cagtttcagc ggcgagttac cgctggaaca
     3541 ggtcagagag cgggatcagc ttatcctttc cgtgatggac aatatgcaac gcattatcaa
     3601 ctgccgggca ggcacgctgg cgcatttgcc ggattacggt ctgccggatc tcagtctgat
     3661 ccatcagggg atggctgcgg gtattcatgg cctgatgcgt cagattgaag aaacgctgct
     3721 gcgttatgaa ccacgcctga gtcagataca ggtggagtta ctcccccagc cccgtccggg
     3781 gcatcttaat tacctgatcc acgcgcagct tcccgatacc ggctggatac gctttgatgg
     3841 cgtattttct ccggaaggac gaattgttct gcgtcatctc aaacaacagg agcgggcgta
     3901 ctgatggcaa gtaacgcgaa ttttatcagc cagttcgtca tgggcggcga tccctgtact
     3961 tataaggaat ccggtgaact gcaggctgaa atgagtaaac tgactcaccc ggcccgaccg
     4021 gatgtggact ggcgtcaggt ggaaaaactc tgcctcgcgc tgttccggca aaatggcgtg
     4081 gaactacaga cgctggtctg ttacgtactg gcgataacca gacggcaggg gctggcaggg
     4141 atggcagacg gactcggctc actggatata ctgctccagc gctgggctga cttctggccg
     4201 gtacaggtac attccagaat atcactgctc agctgggtca cagaaaaaat gcagcaggca
     4261 ctgagaacgc tggatattca gtatcaggat ctgccgcaga tctaccgttg tgtacagcat
     4321 ctttccgcca tcgaaaccac gctgcaacag tgtgaactgt ggcatatgac gaaactggat
     4381 gtgctggccg ggcagtttcg caataccgca ttgcgtctgg aacggctggc gcctcaggga
     4441 gcggaaacca ctatcactcc ccctgaatta ccccgccggg aaatgaatca accgaaaaag
     4501 tcagaagaaa gtccacagcc ggtttttgca acgagacccg ctcagcaaaa cgataaggat
     4561 gccagtccac ccgtgtcatc ccctgaaatc tcccgacagc ggacatggcc gatatttatg
     4621 gccggaatgg ttgtgatggc cggtctcggc ggaacaggat tatggggctg gtcgcagctt
     4681 aatcagccgg acgcgctaat ccagcgaata caactgtctg tcatgccgtt gccgcagtcg
     4741 ctggagagcg gcgaactggc aaagctggat gtaaaggata aggcgctgct ggctcaggac
     4801 agaacaattg cggcaagtca gatgcaactg gagcagttaa acaaattacc tgcccgctgg
     4861 ccgctggagc agggatatcg ccagctacgc cagcttgatg ccctgtggcc ggataatcct
     4921 caggtcaggg cgctgaacgt gcagtggcgt aaacagcggg aactgagcgc cctgtccgca
     4981 gaggcactga atggctacgc acaggcgcag agtcagctac agcgcctgtc ggcacaactg
     5041 gatgcactgg atgaacgtaa ggggagatat ctgaccggtt cggaactaaa aacggcggtg
     5101 tacggcatcc ggcagtcgtt aaaggagccg ccgctggaag aactgcttcg gcaactggaa
     5161 gagcaaaaac agaccggaga gatttcgccg acgctgttga cgcagattga tacccggtta
     5221 aatcagttgc tgaatcgcta tgtcatttta ctggatacga aggtggaaca aagtcagtaa
     5281 acatcggggg atttatgtac caataaggga tatgtgacct tgctattttt taaaaggagt
     5341 ctttgtgtac aaaaaagaga ggaacaggcc attcgatcta ctcgttgatt cacatcagat
     5401 aatgagtgta tatttcggta gatagcttgg gttcgggaac agtgaatacc ttaagtttca
     5461 aaagattgga ttaacctctt gactgtggcc cccgcaacca atttattaga atgctgacaa
     5521 accgcaatgt gttctacaaa ttgcggtttt tttgtattta aaatctttgt tcgctgaact
     5581 cacaacacgt tttttatctt ccttcctgcg aagtaatcaa ttatcgactg ggcaacgtgt
     5641 atcccggttt gctggtatga ctcaacggtg gcggccgcaa tatgcggcgt tgtaatgata
     5701 tttttggcat gtagcagtgg gctaaattgc gccaacggtt cagagctaaa cacatccagc
     5761 gccgcaaaca catttcgttc ttcaatcacc tgaagtaaag cgccctcatc cagcaacttt
     5821 ccccttgcgg cattgatgat cagagcacca ttgcgcatca tcgacaaata tttatgacta
     5881 atgaagttct ccagctcaga agaaaaaggc aaaagaacaa tgatggcatg cgactgcata
     5941 aagatatctt caattgatac aaactgaact ccagctttgt cagcaacctg atagtcgggt
     6001 tgtttgtcaa aagctaaaag ctcaacatca aaaccggata accttttcgc cagaatttta
     6061 cctatattac cgtagccaac caggccaatc cgtttccctt gtaattcaca gccatgcgac
     6121 tcaccccagt agccattttg catcgcatga tagctgccag ggatatttct catgctcgcg
     6181 aagataagtc caatgataaa ttccgcaacc gcatttgaat taatcccaac cgcattattg
     6241 acaacaatac cggattgctg tgccgcacga agatcaatat tgtctatccc cgtcccgaat
     6301 ctcgatatta ttttcacacc agacagcaat gatagcgtgt ccgcctgata acaatctttt
     6361 ccggcgatga ccgcgcaaat agattctcgt aatgcagtgg attctgattt aagcagatgc
     6421 tccacattat tcttaataat aagattaaaa ttattctctc ttagcaactt gctggcggaa
     6481 acacagcgtg ctgaaaagct ggggacggtg accagaacat ttttcatagc ggacactcac
     6541 ttcaaagaac gccaccccaa aagatggcgt gaccggttac tgtatttata ttttgaaatt
     6601 atgaatttgc tttaatgccg agtgcacctc ctggatgata taagccgaaa tcagcacgag
     6661 taaatttttt caattcagag agtgcaagcg ccaccgcatc accaacaacc agaacaacag
     6721 tcgacgagca tgacggtgct aaacctaaat tatccgcctc acttttgacg gggatttcaa
     6781 cagataaatc acaacttatc gcaagcgatg agtggtgact gcgggtaaaa gagatcaaat
     6841 aattacccat ttttttcaga ctaggcagtg tcgccaggat ttccgccgtc tcaccactgt
     6901 ttgaaataag aataacaaca tcgtctttcg ccaccattcc aaggtcgccg tgtacagctt
     6961 ccgtaccgtg aacaaaaaac gagggagttc cggtgctggc aaatgttgcg gcgagtttcc
     7021 tggcaataat accggactta ccaacaccaa taaaaacaac ttttccctga caagattgta
     7081 atactttaat taaatttgcg acctccgaaa gaggggaatc aataacttct tcaactgctt
     7141 tatgttcgtt acgcataaaa tgtttaatga gatggataag atccgtgtta ttcattttta
     7201 ttctccctga ttaatatttt taattacact cacaagacgc gtaagcccca tatataattt
     7261 ttctcgactg caggccaggt tcagacgaag gtagccctcc ccctccgttc catagacatg
     7321 ccccgccata atgcccactt tgccttcatg aattaatcga ctgtagaatt catcaaaagg
     7381 ataaccaata gcagaacaat ctatccagga aaaatagcaa ccatcagctg gccttacgat
     7441 caattctgga atattttcat tcagatactg ctgggtgaat tgaatgttag aggcaatatg
     7501 tgcctttaat gactttaacc atccctcaca ttcgttatag ccaataatag ttgcaattat
     7561 attcagtact gatggggagt ttacaaaatc gcgatacctc gatatcgttc tgaacttatg
     7621 attaaaatta tcgtcagttg aaatcatata cgatcctgtt agtgcaggaa cattaaatgt
     7681 tttcgatatc gagttaaata ctactacttt ttcttttttt attttaagcg cggatgtaaa
     7741 gctacgatta aaaacaaaat cactatggat ttcatctgaa cataaccaga cattatgcct
     7801 tgtacagctt gcagcgattt tatgcagttc ttcttccgac cagactgttc ctgtcgggtt
     7861 atgaggatta cataataaca ccatctttgc gcttttaatc ttaagatcaa aatcttgcca
     7921 gttgatagcg tagctcccct cattttttat aatcaaagag gctgtcagaa tatttcgctc
     7981 gctatgttta attacatcaa aaaatgcatt atagacaggt gtaaaaacga gaatattatc
     8041 accatgcgat gtcaataact ctattgcttt tgcaatagag tacatcacac tggggctata
     8101 ggttatccat tcaggtttaa tatctgtttg atattgttga taataccagt ttactatcgc
     8161 attcagatat tcaccatgtt gccaacgact gtaccctaaa atcgggtgtt ccaggcgttt
     8221 ttttaatgct ctggtgatag cgtctggtat cggaagatcc atatctgaaa tagagaatgg
     8281 tagtacatct tttacaccaa atctgtcctc gcaaaagtcc cattgggtac aatatgttcc
     8341 tttgcgggaa acaggagtat taaaaacatc catcagtata tccccatata gttatccata
     8401 tcccgacgca gggcgatgac tttagtgccg ataatgactt gtagggtatt ttgatcaagt
     8461 ttaacaaccg caatcccgcc agctattttt attgcaactt cgtcaatcaa tcccatatct
     8521 gcgattgtta aacgtaaacg agttacgcaa ttatccagtg acttaatatt ctctttacca
     8581 ccaagtgcct taaccatctg ctccgccgct tgcagctctg atttatcagg agttgggata
     8641 tccgctatag ccgtatcttc gtgagcgttc agcgtgacag gactggactc ttcacggcct
     8701 acggtcatca ggttaaattt aagaatggtc caacggaaca caaagtaata aatgaagaaa
     8761 taggccactt cgacacacac cgcgatcggc caacctgttc ttgtgccacg caatacgcca
     8821 aagctaataa attgaatcag atcgccagta aatcccatct tcacgcccat atatggcaga
     8881 accatgttag cgaatccatt cataaaggca tggaagacaa acagcagtgg actgacaaat
     8941 aagaacagaa actcaatcgg ttcgctgacg ccgccaataa tcaccgtaag caccccggaa
     9001 ataagcaatg ctttgatagc ctttctgttt tgagcatgag cagtgcgata catcgccagc
     9061 gcggcaccag ccagaccata ctgaatcatc agtttgccct gctccatttt ccccgccaaa
     9121 tccagcggaa tgaccgcatt ctctttgacg tacgccataa acatgttcag ggtgccgtaa
     9181 tattcttcgc cgccaatcac agccgaaccg ccgattggcg taaagcggaa aactgacgtc
     9241 accagatggt ttaagccaaa aggaatcgtc acgcgttcgg caactgcata gaagaaataa
     9301 ccaacaggac cggaagttga aatccagtgt ccaatgagca tgaaaagatt gaaaaacggc
     9361 ggccagataa aaggaatgat cagaccaaat ccactcatca caatcagtgt aatgataggc
     9421 accagacgtg ggccgctata aaaacctaac gattcaggaa tgcgtaaatt aacgatcttt
     9481 ttatacatgc tggcgactaa taacccagca acaattcccc ccaacacgct ggtattgtag
     9541 gactggatcc ccagaatgat ggtttgccca tgtgtcgaca tttggtcagc aacgaccaat
     9601 aagtcgtgct gtttaagata aaagttcgtt cccagatgca tcgccataaa accaattaag
     9661 ccagaaaaag caccataggc tttatcctct ttatctttta ataatcctaa gggaatcgct
     9721 atcgcaaaca atacaggtaa attaacaaag gcaaacaaac caagactaac aatgaaatca
     9781 agtatggttt taattattgg gatagccaga aatggaatta actttgccat atcatcactg
     9841 gctaaaccac ttcccagccc tagcatcatg ccacatacac ttagcagagc aatgggatac
     9901 ataaatgcct tccccaggct ctgaaaaaaa ctccaggctt tcttttgttt catgtgggtt
     9961 atctcatata aatgttatat ataattagtc cattaatact ttggtacgaa tagagagata
    10021 tagtttttct tctaaaatta attcatattt aaaagtggca tacagatacc gttcaatttc
    10081 atgaattgcg cgctgtaaca ggatgtcctt ttcaagaaac tgttcataga tatcaccaat
    10141 atctttctgt tttatttctt cattgcataa cacgcgactt gaaaaatatt taaggtgcat
    10201 cataaatctg gaatagttaa atgaacttct gtccaccttt ctgttataaa caacttcaat
    10261 aagccccgtg attatttgcg acaactcaat aattcgtact gattcataat caactgaatt
    10321 ttcataatta tttaaaatat gcaatgctat aaaaccaatc tcatcatcag gaagttgaac
    10381 gctgaattgc tcattaatga tagttaatgc atcgcgactt atcgcatact ctgctttgta
    10441 caacgctttg atttcatcaa ggaaaacatt attaatttgt atacctgaag cgactcggga
    10501 tattgcattc gaaatgtgat ccgcaagaat caatagtagc gatggattga gatttttttc
    10561 gagatttttc tccgcatatt gcactatttt ttcggcaaca aacacatact caatatctac
    10621 atgttcaatc aatttataga gtttgttttt ttgttcattt ctgacataaa aaatccggtt
    10681 agccggatgc tcagggaccg acattccata ttttttgttg taaccgacgc caggcccaga
    10741 aatgataacc tcctgtccat tcatcgatgc ctgtacacaa ttattgttca tgactttttc
    10801 gatgatcatt ccatggctcc aaaaaaaaag gcaaggcacg tcagaagtaa taactacttc
    10861 aaacattgcc ttgcctgatt taacagttac aagatgatta actaatgcgt atacattaca
    10921 cggaattgtg cttaattaaa gagatggtcg gcttattttt caagccgaca ttcaaatatc
    10981 cgacatcagt cacaaaacca gcgtctaata ttcaggtaaa tgttatctat tcgacgaaat
    11041 ataaattcat tgaataaata aaaacattat ccccttctcg ccagcgtcgc cccatcggca
    11101 aaatacgctt taattcccgc aagaatagac tccgcaactt cctgctggaa agtcgccgtt
    11161 ttcagtttac gctcttcctc aacgttactg ataaacgccg tttcgaccag aatggaggga
    11221 atatctggtg cctttagtac ggcaaaccca gcctgttcaa cttgattttt atgcagcttg
    11281 ttgattttac cgagcttatt cagcaccgct ttaccaaact taaggctgtc ggcaatggtc
    11341 agcgactgca ccatatcgaa catggtgtgg tcgacatagc ggtcaccgct tttgcttacg
    11401 ccaccaatca agtccgaggc gttctgggtt tgtgccagat attttgccgc agtactggtt
    11461 gcgcctttgg ttgagagcgc aaacaccgag gaaccgctcg gctggcgact ggtaaaggcg
    11521 tcggcatgga tagaaacaaa caagtcagcg cgctgtttct gggcttttgc tacgcgcact
    11581 tgcaacggaa tgaagatgtc ttcattgcgc gtcatgtaca ccttcatatt gccctctttc
    11641 tcgatcagag agcgcagacg gcgagctatt tgcaatacca cgtctttttc gcgtgttttg
    11701 tatttcccca ccgcaccgga gtcttcgcca ccgtggccag ggtcaagcat aatgacaatc
    11761 ggacgatccc gccctgcttt acccggttgt ggaccacttt gtgctggcgg cacctgcttt
    11821 tcgaggtcgc ctttgttgta atcctccagc agcgccagca gcgggtcctg catatcctgt
    11881 gcattggccg gatagaggtc catcaccaga cgctctttaa acccggcgac cggcgcaagg
    11941 gcaaacagct gcggttttac gttttgcttt aattcaaaaa ccatacgtac ggtttgcggg
    12001 tcaaattgcc cgacgcgcgc cgacttgatg aacgggtcgt cagcgcggat ttgcgcagcc
    12061 atccccttga gcactgagtt caggtttaca tcttcgatat ccaccaccac gcgttcagga
    12121 ttactcaacg cgaactgctt atatttcagc tgacgatttg attctaccgt cacgcgggtg
    12181 tagctggacg caggccagac gcgcaccgcc acgacctggc tgaccgcagc caggctgacc
    12241 tgacttacgc tcaatagcca catggcaccc gcgccttgca gtaaacgacg acggctgatt
    12301 gcagtgttgg atcctgacat gcctctcccg agcaaaagaa atctaagctg tgtaacaagt
    12361 aaacgaccaa tttgaccgga aactttagcg aaagacgcat aatctgtcat ctataaaacg
    12421 gtaaacattc tttttatatt cacggtatta ctgataaaaa actcgctccc gcataaaatt
    12481 tacacttgca ccctgcgaaa aaacagaata aaaatacaat aatttagaat aatcatgcaa
    12541 agaggtgtac cgtggtaaag gaacgtaaaa ccgagctggt cgagggattc cgccattcgg
    12601 ttccctatat caatacccac cggggaaaaa cgtttgtcat catgctcggc ggtgaagcca
    12661 ttgagcatga gaatttctcc agtatcgtta atgatatcgg gttgttgcac agcctcggca
    12721 tccgtctggt ggtggtctat ggcgcacgtc cgcagatcga cgcaaatctg gctgcacatc
    12781 accacgaacc gctgtatcac aagaatatac gtgtgaccga cgccaaaaca ctggaactgg
    12841 tgaagcaggc tgcgggaaca ttgcaactgg atattactgc tcgcctgtcg atgagtctca
    12901 ataacacacc gctgcagggc gcgcatatca acgtcgtcag tggtaatttt attattgccc
    12961 agccgctggg cgtcgatgac ggcgtggatt actgtcatag cgggcgtatc cggcggattg
    13021 atgaagacgc gatccatcgt caactggaca gcggtgcaat agtgctaatg gggccggtcg
    13081 ctgtttcggt cactggcgag agctttaatc tgacctcgga agagattgcc actcaactgg
    13141 ccatcaaact gaaagctgaa aaaatgattg gtttttgctc ttcccagggc gtcactaatg
    13201 acgacggtga tattgtctcc gaacttttcc ctaacgaagc gcaaacgcgg gtagaagccc
    13261 aggaagagaa aggcgattac aactccggta cggtgcgctt tttgcgtggc gcagtgaaag
    13321 cctgccgcag cggcgtgcgt cgctgtcatt taatcagtta tcaggaagat ggcgcgctat
    13381 tgcaagagtt gttctcacgc gacggtatcg gtacgcagat tgtgatggaa agcgccgagc
    13441 agattcgtcg cgcaacaatc aacgatattg gcggtattct ggagttgatt cgcccgctgg
    13501 agcaacaagg tattctggta cgccgttctc gcgagcagct ggagatggaa atcgacaaat
    13561 tcaccattat tcagcgcgat aacacgacta ttgcctgcgc cgcgctctat ccgttcccgg
    13621 aagagaagat tggggaaatg gcctgtgtgg cagttcaccc ggattaccgc agttcatcac
    13681 ggggcgaggt tctgctggaa cgcattgccg ctcaggcgaa gcagagcggc ttaagcaaat
    13741 tgtttgtgct gaccacgcgc agtattcact ggttccagga acgtggattt accccagtgg
    13801 atattgattt actacccgag agcaaaaagc agttgtacaa ctaccagcgt aaatccaaag
    13861 tgttgatggc ggatttgggt taagcgatgc aaatcgccgg atgcgacatg cacaacattc
    13921 ataggtatga taagacccac atgcgtcgca tcaggcaatt acgtttatcc ccgtgaacta
    13981 aacaacgccg ccagaccact gcgccgctcg gtgcgcgtgg caattgccgc acttaaaatg
    14041 cgctcatcgg catacagcga cagacggcga cgcgcgcggg tcaccgcggt gtaaaccagc
    14101 tctcgcgtta ctaccggcgt gcgttgactc ggtaaaatca acgccgcatg gtcgaactcc
    14161 gatccctgcg atttatgtac cgtcatcgcc cacgtcgttt cgtgctctgg caggcgactc
    14221 ggttgcacag acttaatatt gccgtccggc atcgcaaacc agacgcgcgt cccctgcccg
    14281 cgatccagcg caataccaat atcgccatta aacaacccaa gcgcgctgtc attacgggca
    14341 atcatcactg gtcgaccttc gtaccaacga gagtgcggat gacgatgaat tttgcgcttc
    14401 tgttgcataa attgctcaat tcgctcattc aatccagcca cgccaaacgg tccttcccgc
    14461 agggcgcaca aaagctggta ctcattgaac gcctgaatga ttaaatccgg ctcggcacgc
    14521 gcttgcagca gatccagata acgtccgtaa cccgcaagaa cttcctcaag catcgcaata
    14581 taatcttcgc cactctgtaa aagccgtttt tcgatatcag taaaatcctg ctgaaaaacg
    14641 gttttcactg ccgttttatc acctcggtta atcgccgcag ctaactgacc aatgccagaa
    14701 tcgctgccga aacgatagct tttttgcagc aggcagaggc tgtcgcgcaa agatgccgct
    14761 tctgtgccag ttcctgctgg aacgtggctt cccgtcaggc ggctcaactg cccggcacgc
    14821 tcggcggtaa agcccgcgtt ggcataagcg cagatatcgc ccagcacagc cccagcctca
    14881 accgaggcca gttgatcacg atcgccgaga aagatcactc gcgcatgatc gggcaaggcg
    14941 tcgatcagtc tcgacatcat aggaagatcg atcattgacg cttcatctac caccagcaca
    15001 tcaagatgca gcgggttacc ggcatgatga cgtaaacgct ggctacccgg ctgcgcgccc
    15061 agcaatcggt gcaaagtgct ggcatcttcc ggaatgcgtt tcttttgttc agcggtcagc
    15121 ggtaactgtc gcaaagcctt gccgagagat tcggttaagc gcgcggcagc tttacccgtt
    15181 ggtgcagcca gacggatacg gcagcgttct ccgtcggcca tttgaattaa ggctgccagc
    15241 aacttcgcta cggtggtcgt tttaccggtg ccaggaccgc cggaaatcac cgaaatccgc
    15301 cgcgtcagcg ccactgccgc cgcaactttt tgccagttaa tttcatcgct tactggaaaa
    15361 agtttgtcca gggtttgcgc cagtagagct tcatcaacct caatggcatg attcacttcg
    15421 ttgaaaaaac gtgccactgt gcgctcgtta caccacatgc gattcaaata aagacgatcg
    15481 ccacagagga tcatcggcgt tggttcatct ccccggctga ccgcttgtga agccagcaag
    15541 cattcttccc aattttgtag ctcaccgatt tcactgacac aggtcgccaa cagcggatgc
    15601 gacgcctcgt tattttccag tcgtgaaagc ggcaaacaaa cgtgtccctc tccggcatca
    15661 tgacttaata gtgccgccgc gagggtgacg gcaggatgtt catctcccgc cacggtcagg
    15721 gcaaactgca cgtccagcgg gcgtagctgt ttgtgctcca cagcttccag taattgcttt
    15781 tgcaatttca ttacgcctcc tccagggtca taccggcaaa catctcatcc atcaggtcaa
    15841 tcaacccggc gttgggtcgg gtcgcgtaga tcccttgttg cggatgttct ttatcaacgc
    15901 cacgcaggaa cagataaata acgccgccaa agtggcgctc atagtcgtaa tcagcaatac
    15961 gatggcgcag ataacggtgc agcgccaggg tataaagctg atattgcaga tcatagcggt
    16021 gtgcctgcat tgccgctgcc atagcctgtt gggtgtaagc cgaactgtct tcacccaacc
    16081 agttggattt atagtcgagc aggtaataac gcccttcgtg gcggaacacc agatcgataa
    16141 agccttttaa catgccacgt acctgcatga actccagcgg cgggcagcca gcagatagcg
    16201 ggtcaaactg gcgaattagt gcatcaagct ggctggcgat gagcggttcg ctaattggca
    16261 ggtaaaactc catctccacc tgtttatcgc gatcggaaag ctgactcagg ctaatacccg
    16321 tttcattgag aggtgccagg aggacagccg tgatccactc agtcaacacc ggttcccact
    16381 gcggttcaaa gccaccgagc tccagttttt cctgtaccca gttcgggtca accggctggg
    16441 taaaatcgag gtcttcaaac aaactgtgca agaatgtccc cggtgacgca ccgcgcggga
    16501 actgatgcgg tgttaacgtc ggtacttcaa cgacgctgac cacgcctgcg gcatcaacat
    16561 ccaaccgtgg catcagatcc tgagcgatac cgtgaccacg ctgctgcaaa ccggagtagc
    16621 tggtgacacg ccagttatcg ccgggcaatc gttgtagcgt cctcgcattc agttctgcag
    16681 ttaatgcatc attaacctgc cagggctggt tatcaccaat ttgtgccgtt tgccaggcaa
    16741 tatcatcatc gcacaacgct tcaatgcagg tacgaagccc tgccacatct tgcggttctc
    16801 ctttttgcag caaacgcccg agcgcacttt ggtggacgtc ggtatcacct tttttatcgc
    16861 cacgacggcg caccagcggt gcaacgccga gactgcaatg ccaaaccgaa cgcgtcagcg
    16921 ccacgtaaag taaacgcaga tcttccgcca gacgttcggc ctccgcgagg tcgacgcttt
    16981 ctggcgcagc attaagatcc agaacggcct caaacgagtg gcgatcgtga taaaacgcct
    17041 gatcctggac gcggaaattg gtaataaatg gcaaccagac cagcggatat tccagccctt
    17101 ttgatttgtg tatcgtgaca atctgcacca gatgtttatc actttcgagg cgcatttgtt
    17161 ggctggaggc attactgtct ggctcgagga tatgttgcga taaccagcgt accagcgcat
    17221 gttcactttc cagctgcgtt ccggcttctt gtagcagttc gctgatatgc aagatatcgg
    17281 taagacgccg ctcaccgcct gccgttgcca gcaagttttc tgcaatgtta cgcgccgaca
    17341 tcagcgcccg cagcatcggc ataacgccac gtttgcgcca gatttgccga taaccatcga
    17401 actcttcgac taccgcatcc cacgcatgtt cgtcattatt cagcgtttca atatccagcg
    17461 cattcagccc catcattgac gttgccagcg cactgcgcag ggtgttctca cgttcgggcg
    17521 tcatcaccgc ctgcaacagc caaagcatct cctgtgcttc cagagtttca aaaacactgt
    17581 cgcggttcga aaggtaaacg gaagggattt ccagcagcgt taaggcatcg cgcacctgag
    17641 cggcctcctg gcggctgcgc accagcacac tgatgtccga agcacgcacc ggacgcgcat
    17701 cgtcgccgtt catcagcaac gcttcgcccc gctgtccggc ttgtagccag tcgcggattt
    17761 gcgcagcaca tacctgcgcc atggtacttt gatagtcgcc aacgccgcag ctttcgcctt
    17821 ccatcagcca cattttcatc gcaggctgca tttcaccttt aaacacaaag cgtaacgcct
    17881 gatttttccc ggcagatttc acaggaataa acggtatttc acgaaacatg aacgcgtcat
    17941 cagtctggct gaaaagtttg ttaacgctgt tcaccattcc cggtgcggaa cgccagttgg
    18001 tatctaaggt gtagtgagca tgaacttcgc tacgcgcctt catataagtg aagatatccg
    18061 caccccggaa tgcatatatg gcctgtttcg ggtcgccaat cagcaacaat gcggtttccg
    18121 gctgatggtg ccagatacgg cgaaaaattc ggtactgctg ggggtcggta tcctgaaatt
    18181 catcgatcat tgccaccggg aatcgcgtac ggatcgccgc tgccaatacc tcgccgcttt
    18241 cactacgcag cgcggaatcg agccgactta acatgtcatc aaaacccaat tcgccacggc
    18301 ggcgtttttc acgcgctact gtttcgcgga tctcagccaa tgcgcgggtg atcaccagat
    18361 cgcggatcga caatggttct gcaagcagtt gatcgatcgc ctcaaacagt ggatgtcgcg
    18421 gggtttcccc cccggctttc gtgcgatctt ctaagaaacg ctgagagaat ttttccagcg
    18481 actccggcaa ctgatagcta ttggtctctt cttctgccca ggcgctgatc ttctcgatcc
    18541 atttagcctg attgctacgg ttaaacttgc gtcgatcaat accagaagat tcgatcagcg
    18601 catccagttc acccactgcg tcgcgccact gctgttttac ggcatcaata cgcgccacaa
    18661 tttgcgcgtg gcgggaagcc agcgtttcat catcgggggg cggtgctttg ataactggcg
    18721 cttcgccttg cagataacga ttaatatcgc gcagcaacgc ctgcggccct ttccaggttt
    18781 caaagacgac ctgggcaatt tcacgcggca gcgggtagca gtggcgacgc cagaaatcgg
    18841 cgcaggcctg gtagcgtagc agagactcat cttcaatcag ctgctgctca aacagcatgc
    18901 cggattcaaa ggcattcagg ttgagcatgc gctggcaaaa gccgtggata gtaaagactg
    18961 ccgcttcatc catctgccgc tcggctaaca acaaccactg cgcggcttgc gctttatcgt
    19021 cgatctcttc cagcaggcgt ttgtacagtg gattgtcggt ggtttcacgc agacaggcga
    19081 tgcgcaactc gtggatattg ctacggatac gaccacgcaa ttctgccgtg gcagcctcgg
    19141 taaaggtcac caccagcagt tcttcaacgg tcagcgggcg gggaaaggcg gccgaaccgc
    19201 ctagtccaag taacaggcgc aaatagagcg ccgcaatcgt aaaggttttg cctgtgccgg
    19261 cagaggcttc aatcaggcgc tcgccctgta agggcaagcg caaaggatct agtgtctcgg
    19321 cgacatcact cattcttttc actcatcagg ggcattgttt gctgcaacgc gctgacgttc
    19381 tcccacactt tccagccttc aggatgcaca tattcggctt tcccattctg gctgccggaa
    19441 atctgcgaca gaatagccat accttgcggc tcgaccaccg cctgatggaa gaaatcagca
    19501 attttttgcg gcgtcagcag ttttatctgg gccacgattt tatcacgcga atcgaagcgc
    19561 atattgccgc gatcgaaatc tttacttaac ttcgatgctt cttcgccgag cgtttgcggt
    19621 gcctgcagca tctgggtaat taccgcctgc tggatttgcg caaactcttc tggcttcatc
    19681 gcccgcaatt ttgcctctgc ggttgggaaa aacgccttgt aacgctccca caagaatgaa
    19741 ggctgtttat cattgctttg caaaaggaag cccatgcccc actgacgccc cacgctcatt
    19801 ggaaacgcaa acacggcata gcccaactgt tcttcggtac gcaactgatt gtagaaccac
    19861 ggctgtacga tctgccccaa cagagaacta tacgctgagc tggtgtattc atcgtagcca
    19921 gtcggtacaa ataccgctgc cagtgcggag tcggtgctgt taccggcttt ttcaaagatg
    19981 acggattgtt ttttatcgac cacgacatct ttgttacgac accactctga accatcagcg
    20041 cccaactgtt tttgcacatg gcgtgccagc gttattgcct gggcttcagt catgttgccg
    20101 ataaccataa actctggtct agcccctgat tttaaggcgt cgcgataggc cagcacctct
    20161 ttcaacgtaa tggagggcaa aattttgcgc cgttcatctc gcgagaagta cggcacttgc
    20221 gagagcatct gcgcgggcat aatcgcctgc tcgaacgctt tgcccttttc tgcggaatcc
    20281 atcatctggt tataccagga cttcgcctgc tcaagctgat cttccgtagc ggtatagcta
    20341 aagtagccct ccagcagagc ctggaacagc tgcggcagac gctgggtgta accattagca
    20401 ttaaccataa ggccgttgtt agcattggtg gaaaaactta tgccaccaac cgacgcctgg
    20461 ttgcttaact gatcaagcgc cagccctgcg agataatcat tgagtgcaaa catcacctga
    20521 ttgcgggcgc tgtccatggc tttcggatta cgcaaaatca ggctgacatc agctttgggc
    20581 tcgctggcaa aataacggct tggcgcatac accacgcgca gattcgactc atcaacaatc
    20641 aactctggat ggtcgtattt cttctctgac ttaatcagcg agaaatcgtc aggaatatag
    20701 gggttaagct ccggtaagga gagcgcaata ttggcggctt ttttctgcca gtcagcgaaa
    20761 gtttgtgcgc taattttatc gacctgatac ggcgcatcga caaagtaagc cgttttgttg
    20821 tgcggctctt tcgggctgat ataccagata cgcgcattct gtggcgtcat catcgccaga
    20881 cgttctttta ccgctttagc gtcgtaccga tcggcaatat tgactgcatc cagtgtatgc
    20941 tcaacaggaa cgcgaatcat ggtatctgcc agccattcga cgtaatccat atcacgggtg
    21001 attgacggat aacggaagtc gatatccagc acattcgcca gttcatcgaa gtattgttta
    21061 tcgatccctt tttcacgtaa cagattgagg tagctaaaaa tggccgccac aacctgatcg
    21121 cgattcgcca gacctttatc ggttaaagac gcagagatcg ctaatacgcc gctgttgccg
    21181 ttgacgatag gatcggaatt ggcgctaatg ccctcaacta atccctgctt ttgcagccag
    21241 tcagaaagtg taccagggct gcgattacca atcagatagg taatcaattc atccgtttta
    21301 ctacggaact tcgctgaatt gttatcgatg cgaaactcaa cgcgcagaac tttacgcggc
    21361 agcgccggga cgtaatgaat gataatgccc ttttgcgcgt cggtgactac cggcacggtg
    21421 atttccggtt ttttgctctc tttgttcggc acgcgaccaa aggtgtccgc cgccattttc
    21481 gccaactccg gcaacggttt attgctgtaa ataaccgcct tcatcagatt ggcggaatag
    21541 tacttctcgt ggaaatcttt cagcgcctgc tgtaccggat tacctggttt gtcgcttaaa
    21601 gtttcgaggt taccaccaga aaactttgaa ccggggtgtg ccgggttaat ggtttctgcg
    21661 ctgacctgtg ccatgcgcat cccgtcacgc gtacgcgcca tggttaattc ggcattcact
    21721 gcattacgct cacgttcggc gtatttcttg tcgagcaagg gttctgcaat agcatcggcc
    21781 aggcggtcta ccgcaccggg taaggcatcg ttctcaactt ccagatagaa agccgtgcga
    21841 tacggtgccg tgctggcatt gtgactgccg ccgtgcattt tgagatattc ggccagactg
    21901 tcagcctgcg gatacttttt cgaccccatc agactcatat gttcaaggta atgtgccagc
    21961 ccctggtacg cctcaggatc ttccagcgac ccaacgggca ccaccagcgc cgagagcgat
    22021 ttaactgcct gcggatcaga aaccagtaag accaccatac cgttatccag acgtatagcc
    22081 tgatactggc ggttatcttt atcactttta cggatggttt cctgaatcgg ctgccatccc
    22141 gtttctgcct gacttaaggg tgcccagagg gcaacaaaca acaataatgc tttgaaccag
    22201 atgctgcggg gcattcacgg acctcataat caactttatt ttctggccag attcaacacg
    22261 ttaacgcaaa tcatctgcca gaatttaatc ttgtgctgaa cgagtcagcc tatgtctata
    22321 taaccatcag tccgtgactg gtgcgcatca taaagtaagc ggatagattg cgcaattttt
    22381 atacaacact catgactgat taaagcgaaa cagcggtaac aggaaacgtt gcgactgttc
    22441 aacgatagcc tccattgtct ctggtgttaa ttgccgccag agccgttgat accagatatc
    22501 atcaccttcg ccacgcacca tcatgttgcc ttcgtaagcc tgaaggaatt tcgtacgggc
    22561 tttttgcaac gtggaatcgt catccagcat ggcatcgttt tgcgcgtcat aacaggtttt
    22621 tagccacgcg ccgccacttt caggtaacac cagcaatggc gcggacattc cttcacgata
    22681 cccctcaatc agttgtgaga ggtaatgcaa agcctgttcg gctgcaagcg gcggaaaacg
    22741 ccactcgccg tctttgcgta gaaaaaggcg actttcacca ttaccaccgc tggcacagta
    22801 gacaaggtgt tccagccaaa gttgcattcc ctgcgccaca cttaataaag agggacgcca
    22861 gcgcaacagg ccatccggct gcacctgcgg caaccagccc gttatttgca caccgttgca
    22921 ggcgagatca atctccatac tctgccccgg ctggcgacag gcaatgactc tgtcggcaag
    22981 ctgctgcatc tcctgacact gcgtttccca gaaaatttca ccaaaagcgc catacggtaa
    23041 atcccctgcc gcccggaagc gacggaacaa gcgttcggca tcatcctgct caaccagtgc
    23101 attcaataac tgctgattga tttgataacg gctaagtcct tccagaataa atggctcggt
    23161 gtcggggatt tcgctgtctt cggtacggaa gttcacctgc aaacgcatct ggaaaaatgc
    23221 ccgcaccgga tgtgcccaga atcgttgtag cgtttccagc ggcacggttt ccggtaaggt
    23281 aaatggcagc ggctgaacaa attcagaatg tgctttacca gcctggctgg ccgcaggtag
    23341 ccattcacga gcataacttt gtcgttcgcc tggctggtag ttttgtggat caaacggcat
    23401 tcgggtatgg aggcaagtaa gatgcgcttt tacccttgcc tcgctttcat cacagttgag
    23461 cgcttcatcg cccggtagat aatggctttg cccgatgtag tcgatcagtt cctgcaccag
    23521 taccgacggg aaacgttcac tgttatcctg aatggaacgc ccgatatagc tgatatagag
    23581 tttttgctgc gcggaaatta acgcttccag gaacagatag cggtcgtcat cgcgacggct
    23641 acggtcgcca cgcttcggtt tctggctcat cagatcaaag cccaatggcg caagctgacg
    23701 tggataaacg ccgtcgttca ttcccagcag gcaaaccact ttgaacggaa ttgaacgcat
    23761 tggcatcaga gtacaaatgt taaccggtcc ggcgagaaaa cgctggctga tacgttcttg
    23821 atccaggcgc tgtgccagtt catcacgcaa tagtgacagc ggcaccgcgt cgccatactg
    23881 cgcacctaaa ccttcggcga taatcgcctg ccattgttgt tcgatcagcg tcatcgccgc
    23941 ttcggtttcc gcatccggca ggaagaaggc gttgagcata tcgcgacaaa ccggcaacca
    24001 ctcttccagc ggacgctcct gcgccagccc gcgacgccag atatttagct gcattagcag
    24061 tgaagccaga tgccccacca gttctgcaat taagccgctc gattcatcat aaggtagaac
    24121 cgattgccac tcgccctgcg cgctctccat cgcgtagccc agcaacatgc gcgtcaggcc
    24181 aaaccgccag gtgtgttgac cggtagcggg aagttccagc tcgcgaacgt tgtcgtcatc
    24241 tatcccccaa cgaatgccgg actcgttgac ccactggcgt aaataacgca gcccttcttc
    24301 ggtgatgtca aaccgcgccg ccagcaccgg cacatccagt aatgccagca cgtcttccga
    24361 cacaaagcgg ctgtctggca acgataacag gctgataaac gcttcaagta caggatgcga
    24421 ctgccgcgcc cgacggtcgg aaatggcgta aggcaggtaa cgatccgcag gtgcgctacc
    24481 aaacacagcc tgaataaacg gactgtagct gtcgatatca gccaccatca cgatgatgtc
    24541 gcgcggagta agtgtcgggt cttcctccag catcgccagc aggcgatcgt gtaaaacttc
    24601 aacttcacgc tgcgggctat ggcaaacgtg gaaggtgata ctgctatcca gtggatcaag
    24661 cgggcgtttg ttatcgctac gggaaaactc ttcgatgttc acaccagcaa cggcgcggtt
    24721 ttccagttcc agaatgtcag actgaatatt atgcagcagg ttatctggcg tcacatcgac
    24781 aaaagcgtcc agctcctggc tgctctccag gtcagaaagg agataaatgt agtcgcgccc
    24841 aagcttgccc catgaagcca gcagcgggtt gccgacatcc tgttcaccat cgctgttaaa
    24901 gagctgcccg gcattttcgc tgtcgcgaaa tagcggtaat tcgcgatctt caaaactgtg
    24961 tcggcgctgg cgagtcagta gtttcgccag ataagcggga tctttaatgt cgccccagta
    25021 ataacggcag gggttggtaa acaggagatg gatttcaata tgtttaccca gcgcctgtag
    25081 cgcctggaga taaacaggcg gtaacgcgga aataccgcat ataaagacgc gcgaaggtaa
    25141 ccccggcggg caggtcgtcg cggactccag cgtttcgata aagcgctgat agagattggc
    25201 gcggtgccag cgcggttgcc caagttcgtc ggtatattcc accaacgcct tccacaacgg
    25261 cgcttgccag gcctgtgctt ctcccaaccc ttctaccaga tgtcctgttt cccactgtgc
    25321 cagccagtcc ggacgataga ccagatactg gtcaaacagg tccgccgctt ttgaagaaag
    25381 ctggaacagt tttcgcttgt cactatcgtc agtcagataa tgccgcaaca gggtaaagtc
    25441 ttcgcgctcc aacagttgcg gcagcagtgt catcagtttc cagctcatgc tctgtttgtt
    25501 aaaggcgctc tctttgggga tctccggtaa cacccggacg aacatatccc agataaagct
    25561 cgctggcagc ggaaaatcaa tgtttgccgc aataccaaac ttttgcgaca gggtcatttg
    25621 cagccactgt gccataccgg tactttgcac cagaatcatc tctggttcga aaggatcgtc
    25681 cagccgttcg cgttcgacaa taaactccat caacgcttcc agcacgtcca gacgattgga
    25741 atggtagacc cttaacatag cggctcctga ctactgacga ttcgggcaat gcaggcgggt
    25801 catctcgcct tctctgcccc cgggtgaaac tagcgtaacg ctgatgctga cacatcccgc
    25861 ctgcgatgtc tgcattcggt tgacctgcca gttagcaggt ggcgaaatcg cgcgcagttg
    25921 cgtttgctgc cagccatgcc gccagagctg ttggtactgg tttctgctgg caagactgtt
    25981 cattaatgtt cgctggaaac ccgataacgc agtgacaatc atcaccatca acaccatcgc
    26041 caacattacc tccggcagac taaagccttg ttgattcctc agggaagctg acataacgcc
    26101 ctctctttca gcggacaaaa atcgctccag ccgcgtggcg aaaaaacaat gtttccatcg
    26161 atgacttcgc ctgttcgcca caacgaaacg ccttcataac cagcaatcaa taaggcttca
    26221 ttatctgcca gtaaacgcag acaaacccgg gcaccggtgg cagcatacag taagcactga
    26281 actgcgggca gcgtctgcca ggagtgcatt tttccccact ccagcgccga ctgaacgatg
    26341 gcctggcggc gcaatgactg actttccatg ctcacgcgag aagcaaaact gcgatcctgc
    26401 tgactcattc cttgcaatag caagctaccc aaaatcagca gcatcaggac cagagccagt
    26461 gacgaaacac ccttttcgcg gttcacaggt tggatcctgt cacgctatag ctggcatcca
    26521 ccacggtttg cggatcagcc ttgctggcag cgtgcatatt aaccgtcaac accggcgaga
    26581 agccgctgac atcctgacgt acgacctgaa aagtgtcgat aatgatggca tccggattag
    26641 tgactttatc ccagccctta ccttcacagg atgtcgcacc gcgtagcgtt tccagcacat
    26701 gctccttcag acgaaatcca atctggtcgg actcttttac cggttcgcga tcccagatac
    26761 cattactgtt cgcatcccac tgcacaatga cacagtcacc ctgtccgaca atttccagcc
    26821 cttcgcccgt acagctgcca tggcaataac ccgccctctg gagatgcttc gcgacggtaa
    26881 atacccgcag ccagatttca tcttccagcg ccagcttacg ggtgttcgtt aaactttcac
    26941 gctgtaacgc aggcagaaag cgtgcagccc ccagcaacaa tacgctactg atcgccatag
    27001 caatcaacac ttccagcaga gaaaaacctt gctcttttac aggcatcctt ctgtttctcc
    27061 ttgctgacaa agccggagtc ttccccacgg cgaaaccact agccaccact cgcccgttga
    27121 gtttttgaag cgaatatgcc cggcccatgc ggtattgcgc aggccaaaga aagcaagcga
    27181 aggtgtcagg tcgctcattt cgacttcggg ccagcgcggc acaaagacca atggtgaact
    27241 gccatgacag gtattcgccc cagcaacgga actcacaagg caccataacg tcccctccct
    27301 gataagactg atactgtggt cgcggttatg ccagttggca tcttcacgta aatagagcaa
    27361 atagtcccgc gcctggctgg cggtttgcca aagccgttgc gactgctgcc agtattgcca
    27421 gccatagagc ccacttgcgc ttagcatgac cagaatcagc atcgcgacca gcgtttcaat
    27481 cagcgtataa ccacgttgtt ttttcatgcc ggcagtatgg agcgaggaga aaaaaagacg
    27541 agggccagtt tctatttctt cggcgcatct tccggactat ttacgtcgtt gcaggacgtt
    27601 gcaaaatttc gggaaggtgt ctcgaagaat ttaacggagg gcaaaaaaaa ccgacgcaca
    27661 ctggcgtcgg ctctggcagg atgtttcgta attagatagc caccggcgct ttaatgcccg
    27721 gatgtggatc gtatccttca atctcaaagt cttcgaaacg gtagtcgaag atggattcgg
    27781 gtttacgttt gataatcaac ttcggcagcg gacgcggttc gcggcttaat tgcagatgag
    27841 tttgatccat atggttgctg tacagatgcg tgtcgccacc ggtccagaca aaatcaccca
    27901 cttccagatc gcactgctgc gccatcatat gcaccagtaa cgcgtagctg gcaatgttga
    27961 acggcaggcc gaggaagacg tcacaggagc gctgataaag ctggcaagag agtttgccgt
    28021 ctgccacata gaactggaag aatgcatggc acggtgccag cgccatttta tccagttcgc
    28081 ctacgttcca cgctgaaaca ataatgcgac gggaatccgg gtcgtttttc agctggttca
    28141 gtaccgtagt gatctggtca atatgacgac catccggcgt tggccaggcg cgccactgtt
    28201 taccatacac tggcccgagg tcgccgtttt catcggccca ttcgtcccag atggtgacat
    28261 tgttttcgtg tagataagca atgttagtgt cgccctgcag gaaccacagc agttcgtgga
    28321 tgatggaacg caggtggcaa cgtttagttg tcaccagcgg gaatccatcc tgcaggttaa
    28381 aacgcatctg atgaccaaaa atggaaagcg ttccggttcc ggtacggtcg tttttctgtg
    28441 tgccttcgtc gagcactttt tgcatcagtt ctaaatactg tttcatggtt cctcaggaaa
    28501 cgtgttgctg tgggctgcga cgatatgccc agaccatcat gatcacaccc gcgacaatca
    28561 tcgggatgga aagaatttgc cccatgctga tgtactgcac ccaggcacca gtaaactgcg
    28621 cgtcgggctg gcggaaaaac tcaacaatga tgcgaaacgc tccgtaacca atcaggaaca
    28681 agcctgagac agctcccatt gggcgcggtt tacgaatata caggttgagg ataataaaca
    28741 gcaccacacc ttccagcagc agctcgtaaa gctgtgatgg gtggcgcggc agcacaccgt
    28801 aagtgtcgaa aatggattgc cactgcgggt tggtttgcag cagcaaaata tcttctgtac
    28861 gggagccagg gaacagcatg gcaaacggga agttcgggtc aacgcggccc cacaattcac
    28921 cgttaataaa gttgcccaga cgcccggcac caagaccaaa cggaatgagt ggagcaataa
    28981 aatcagagac ctggaagaag gaacgtttag tacggcgggc gaagataatc atcaccacga
    29041 taacgccaat caggccgccg tggaaggaca tgccgccgtc ccagacacgg aaaagataca
    29101 gcggatcggc cataaactgc gggaaattgt agaacagaac ataaccaata cgtccaccga
    29161 ggaagacgcc gaggaagccc gcatagagta agttttcaac ttcatttttg gtccagccac
    29221 tgcccggacg attcgcccgt cgtgttgcca gccacattgc aaaaatgaaa cccaccagat
    29281 acatcagtcc gtaccagtga agcgccacgg gtcctattga gaaaatgacc ggatcaaact
    29341 ccggaaaatg cagatagcta ctggtcatct gtcaccacaa gttcttgtta tttcgctgaa
    29401 agagaacagc gattgaaatg cgcgccgcag gtttcaggcg ctccaaaggt gcgaataata
    29461 gcacaagggg acctggctgg ttgccggata ccgttaaaag atatgtatat gatccgcgct
    29521 ataacccccc acgaatcagc ccgcccatgc cgcgacgctc cataaaggct gcaacctgat
    29581 ggcgaacttc ggtcgccagt tgcgcttcca gactacgctg cgcaagattt tctgcttcgg
    29641 caaaatcaat gcgccgcagc aggtatttta cgcgcgctac agaacgtccg ttcatagaca
    29701 gatggcgata cccaagccca atgaggattg ccacgcacat cggatcgccc gccatttcac
    29761 cgcacaaacg gagatcgatt ccatgtattt ccgcttcccg ggcgatcatc gccagagctc
    29821 gtaacattgc aggatgaaga ctgtcataaa tgttcgccac ccgggtattg ttgcgatcaa
    29881 cggccaggat gtattgcgtc agatcgttgg tgccaacaga gatgaaatcg acccgctttg
    29941 ccagatgcgg cagcataaac accattgacg gcacttccag catgatgccg atacgtggtt
    30001 tgggaatttc gtaaccgatc atctcctcga cttcacgtcc ggcacgttca atcaggcggc
    30061 gtgcttcgtc aacttcatcg aggcttgtga ccatcggcaa cagaatattc aggttgcccg
    30121 tagcggcatt agcacgcagc atcgcccgca cctggatcaa gaagatctcc ggctgatcga
    30181 gcgtaatgcg aatcccacgc caacccaggc atggattctc ttcgctgatc ggcatgtaag
    30241 gcagctgctt atctgctccg acatccagcg tacgcaaggt gacgggttta tcattaaaca
    30301 tttgcagcat cccctgatac tgcgccacct gttcttcttc cgacggaaaa ccactttgca
    30361 gcatgaatgg gatttcagtg cgataaagtc ctatgccatc aatacggctg cccagttttt
    30421 cttcatgttc cgggcttaaa ccggcattga gcatgacttt aatgcgttcg ccgcttttta
    30481 actgggcggg taaattgacg tcatcttccg ccagacggct aagctcgatc tcttcactaa
    30541 ttagccgctg atattcttgc agcagtaccg gctccggatc gaccagcaat tcaccgcgat
    30601 aaccatcgac gatcagcgtc cgacgatgca gtaccgaagg ctgaatatcc gcgcccatca
    30661 cggtagggat ccccagcgca cgtaccatga tcgcagcatg ggagttggca gcgccatcgc
    30721 gcacgacaac accgactaag cgatcctggg gcagctcagc aagcgttgtc gctgacagtt
    30781 catctgccac cagaatgaaa cgttccggcc aggcgttcgg cccttgatta gcgtcatcaa
    30841 gatgaaacag caatcgctga ccaagtgcac gtaaatcgcc agcccgctct ttgagatagt
    30901 tatcgcttag cgcggcaaac tgttcggcaa atttttcaat gaccgttttt accgcccact
    30961 ctgccaccga gcctttatca acctcggcaa acaattcgcg acgcagccgg gtatccgaaa
    31021 gcaggtgtga gtaaagatcg aaaatagccg ccgtttcttt ttgtgcaccg gcagcaaagc
    31081 gtttgctata gcggcgaaac tcgttagccg cctcttccaa cgccccggtc agtcgttcgc
    31141 gttccagagc cggatccagc gttgatgcct gatacacctg ttccattaaa ggtaacgtgg
    31201 catcctgcca gccttcggca atcgccacac caggtgctgc cggtaatgca cggattcgcg
    31261 tctggcgata ttgcccaaac aaggcagtca actgcgactg agaaagaata gctgccatct
    31321 gggtggcaag cgtcaccagg aaggattctt cactttcgtc atactggcgc aactctcgtt
    31381 gctgtaccac cagtacacca agcaactggc gacgttgaat aattggtacg cctaaaaacg
    31441 cgcggaaacg ttcttctttt acggagggga tgtatttgaa gctggggtgc ttttgcgcat
    31501 ctgcaaggtt tatcggttcc gccagcctgc caaccaggcc gacgatccct tcatcaaacg
    31561 cgagcgttac agtgcgaccg cgtggttttt tcagtccccg ggtcgccatc aggtagtaac
    31621 aacgtcgatc atgatcggcc aggtagaccg aacagacctc ggtatccatc gcaagacaga
    31681 tgtcggtaac cagaatattt aacgcctcat tcaggcgtgg tgcgctggct accttttcga
    31741 ctatttcgcg caggcgagtg agcataattg gcgtgactta acctctttta cgtcgataag
    31801 cagatgcgtt ttgtggtttt ggcgtatttt cctgcagtga catcaccaca ctcgcgaact
    31861 ctttcattac cctacggtag acatcacgtt taaatgacac cacctgtctg actggatacc
    31921 agtaacttac ccatcgccag ccgtcaaact ctggtgtact gctggtttgc atattgattt
    31981 ctgcatcgcc gctcaccagc tgcaagagaa accatttttg tttttggccg atacaaaccg
    32041 gcttcgtgtc ccaacgcacc aaacgtttcg gtaatttgta gcgcaaccag ttacgcgttg
    32101 aagcaaggat tcgaacgtct ttgcggctta atcctacttc ttcaaacaat tcacggtaca
    32161 tcgcctgctc tgcggattct ccggggttga ttccgccttg cggaaattgc caggagtgct
    32221 gaccaaatcg ccgggcccac attacctgcc cctggcgatt acaaatcacg atacctacgt
    32281 ttgggcggta gccatcgtca tcaatcaccg gactacctca aaataaagct ttatatacga
    32341 atgattgttt catactccag gaagacggta aaccactctc tgcagggcat tacacactaa
    32401 taacaattga ataactcaca gttatgtgca gagttataaa cagaggaagg ggtggatagc
    32461 cgtttttatt caccttttct gtggatagag ttgtgaagaa ctacggaatt actacgggaa
    32521 aacccggagc attctgaata agacagatat agagatttta aaatattcat tatcagtcaa
    32581 tgtattacat gtgatttgag taataaaaaa gagtaattcg tgacccaggt cacacctctc
    32641 atttacgggt tggcgaaaga tcaaccaacg ccgtatttat ccacagaatg tgccactaag
    32701 ttaagcactg aaccactaaa aactggagtt tcgtcgcacg tcaaggctgt aaatggaaac
    32761 agtagtgaag gtttttcaca gttatcccag ctttctgtgg ataacatggt gtaagatcct
    32821 gtttattttc agtgaccaga tttggaaaac ccgttgcagt gttgcgcaac tcgattaccg
    32881 gcaacctaaa aagcaatata aatcagagaa ttgaacaacg catgtggaaa aagttacact
    32941 gcgaatattc ggcacataat tgctgtttgt tttttaacca aggtatcatg acatgtccca
    33001 acctcgccca ctgctctctc ctcccgaaac tgaagaacaa ttgttagcgc aagcacaaca
    33061 actttctggt tatacattgg gagaactggc ggcacttgcc gggctggtta cgccggagaa
    33121 tttaaaacgc gataagggct ggattggcgt gttactggag atctggctag gtgccagcgc
    33181 agggagtaaa cctgagcaag attttgctgc tctgggcgtg gaacttaaaa ctatccctgt
    33241 ggatagtctt ggtcgtccgc tggaaacaac attcgtttgt gttgccccgt taacgggcaa
    33301 tagcggggtg acatgggaaa ccagccacgt gcgccacaag ctcaaacgcg tgctgtggat
    33361 accggttgaa ggcgagcgca gcatcccgct ggcaaagcgt cgcgtaggat caccgttgct
    33421 gtggagcccg aatgaagagg aagaccggca gctacgcgaa gactgggaag aattaatgga
    33481 tatgattgtt ctcggtcaga ttgagcggat caccgctcgt cacggggaat atttacagat
    33541 acgaccgaaa gcagcgaatg cgaaagcgct gaccgaagct attggtgccc ggggcgaacg
    33601 gattctgacg ctgccgcgcg gattttattt gaagaagaat ttcaccagtg cgctactggc
    33661 ccgtcatttt ctgatccagt agccatcgct ttgacctgcc gctttccggg catataatta
    33721 ccgcttcatt tttttggcag ggctttttag atgttatttg catggataac cgatcctaac
    33781 gcctggcttg cgctcggtac gctgacgctg ctggagatcg ttcttgggat cgacaatatt
    33841 attttccttt ctctggtggt ggcaaagctc ccaacagcac aacgtgctca tgcgcgccgt
    33901 ctggggttgg cgggagccat ggtcatgcgt ctggcgctgc tggcatccat cgcctgggtt
    33961 acgcgcctga cgaatccgct ttttacaata ttcagtcagg aaatttccgc ccgtgatttg
    34021 attctgcttc tgggtggctt gttccttatc tggaaagcca gcaaggaaat ccacgaatcc
    34081 atcgaaggtg aagaagaagg gctgaaaaca cgcgtttcat cattcctcgg cgctatcgtg
    34141 cagattatgc tgctggatat tatcttcagc ctcgactcgg tgattaccgc tgtgggtctg
    34201 tcagatcacc tgtttattat gatggctgcc gtggtgattg ccgtaggcgt gatgatgttc
    34261 gccgcgcgct cgattggtga ttttgtcgag cgccatcctt cggtaaaaat gctggcgctc
    34321 tctttcctga ttctggtggg ctttaccctg attctggaaa gtttcgacat ccacgtaccg
    34381 aaaggttaca tctacttcgc gatgttcttc tctattgcgg ttgaaagcct aaacctgatt
    34441 cgcaacaaaa agaatccgct ctgatactcc gtacgctctc ctgcgggagg gcgtactcac
    34501 tcctgttacc ctcacagttt aagattttcc tgctttcaag atatataacg tcggtttata
    34561 aacagactat tatcataggt gggccaaatg aggataaccg gatgaaaaaa tgggcagtaa
    34621 taatttctgc agtcggactg gcgtttgctg tttccgggtg ttccagtgat tacgtcatgg
    34681 cgaccaaaga tggccgtatg attttgaccg atggaaaacc tgaaattgat gatgataccg
    34741 ggctggtgag ttatcacgat cagcaaggta acgcgatgca aattaaccgt gatgatgttt
    34801 cgcaaattat tgaacgttaa caaataaggt cagcatccgg ctggccttaa gatttttctc
    34861 tttccctttt cccttccctc tgccattttt atattcctta tgtcgtgatt ataaaaagga
    34921 aacggctatg caatatcacc gtatacccca cagttcgctg gaagtcagca cgctggggct
    34981 tggcacgatg acgtttggtg aacagaacag cgaagccgac gcccacgcac aactcgacta
    35041 tgccgtcgct cagggcatta accttatcga cgttgccgaa atgtacccag tacctccgcg
    35101 ccccgaaact caagggctaa ccgaaaccta cgtcggcaac tggctggcga aacatggcag
    35161 ccgcgaaaag ttaattatcg cctccaaagt gagcggaccg tcgcgcaata atgacaaagg
    35221 catccgcccg gatcaggcgc tggatcggaa gaatatccgt gaagcgctgc atgacagcct
    35281 caagcgtctg cagactgatt acctcgatct ctatcaggtg cactggccgc agcgcccaac
    35341 caactgcttc ggcaaactcg gttatagctg gacagattct gcgcctgcgg tttcgctgct
    35401 ggatacgctg gacgcactgg cagagtacca acgcgcggga aaaattcgtt atataggcgt
    35461 gtcgaacgaa actgcatttg gcgtaatgcg ctacctgcat ctggcggaca aacacgatct
    35521 gccgcgtatt gtcaccattc agaaccccta cagcctgtta aaccgcagtt ttgaagtagg
    35581 tctggcagaa gtcagccagt atgaaggggt cgaactgctg gcctattcgt gcctgggttt
    35641 cggcacgctg accgggaaat atctcaatgg tgcaaaaccc gctggcgcac gtaatacgct
    35701 ctttagtcgc ttcacccgct atagcggtga gcaaacgcaa aaagccgtcg cggcgtatgt
    35761 tgatatcgcc agacgtcata gcctggaccc tgctcagatg gcgctcgcat ttgtacgccg
    35821 tcaaccgttt gttgccagca ctctgctggg cgcaaccacg atggagcagc tgaaaactaa
    35881 cgtcgaaagt ttgcatctgg agttgagcga agacgtatta gctgaaattg aagcggtgca
    35941 tcaggtttat acgtatcctg caccataaga ttaacgccgg ttaaaaccgg cgttaaatat
    36001 taatgacggc gctgccagat ccacagcgcc gttattgcca gcgcaaacag cgcaccgaag
    36061 ccaatgccaa tgggcacgac cgggatgcct accattaccg ccagcgagta aatgcccagc
    36121 atcaacaaca tggcgctgtt ttcgccaagg ttttgtactg caatcgcatt ccccgccccg
    36181 acgctttttt taccccgctc ctgtagcaac gcattgagcg gaacgacaaa aaaacccccc
    36241 agcacgccaa tcagcatcaa caaagcatag gctggcagca gctcgtgttg cagggagaaa
    36301 atcagtacca ccacgccaat caaaatcccg gctggcatac agcgtgacac ggtttccagc
    36361 gtaactaact tcgctgccgc acctgcacca accacgatac caatcgctac catcgcgttg
    36421 agataggtcg gcgtagcgtt atcggtaata cccagcgcca ccggtaccca cagcaccaac
    36481 aggaaacgca gcgtgacacc cgctccccag aataaactgg tgcccaccag cgaaaaacgc
    36541 gtttcaccat tgcgccatag cgaggtgcag gcattcagga aactgcgggt catgctgatg
    36601 agattccagg actgccccgg acgcgccgcc gccagtttgg gaatgtagat attggcaatg
    36661 accgcgccac cgtaggccag tgcgcatgcg gccagggcga tcaggacatg ccagtcagcc
    36721 agaacaccac cagctacgga accgagcaaa atcgccgcta tggtagacgc ctccattaaa
    36781 ccgttagctt ttactaactt actacccgtg gttaattcgc cgagaatacc gtatttcgcc
    36841 ggtgaatagg ctgcagcacc aacacccacc aacgtatagc cgagaaacgg attgatacca
    36901 aagcagatac tggctgcgcc cagtagcttc aggccgttgg caaacatcat cacccggcct
    36961 ttggcgaagc tatccgccac ctgcccgaca aacggcgcaa aaagaatgta agcacctaca
    37021 aacaccattt gcaggatggg ctggctccac tccggataga actgcgcttt cagtaacgcc
    37081 agagtagcaa acagtagcgc attatcgcca aacgcagaga gaaactgcgc cacgataacc
    37141 gctttcatcc ccttcgacca caacgaagtg ttagtgtgca ctgactcact catcgtgttg
    37201 ttccgcttcg tctacccagc ttttcaacgt gacaaagtca ggtttgccgc tgccaagtaa
    37261 tggcatctgt ttcagatagc gaatatcgcg cggtacagca agctccggca cgccgtgctc
    37321 gcgggcatac tgttgtaact tatcgcgcgt cagttcgtta tctgtggtga aaagcaccag
    37381 tgcctcgcct ttgctggcat cgctcttaat cgcagtggca tggactttat ctggcgaaac
    37441 accaagtgcc agttgttcca ccatttccag cgacaccatt tcgcctgcaa ttttggcaaa
    37501 gcgttttgcg cggccctgaa tctgcacaaa gccctgctca tcaaaacgca cgatatcgcc
    37561 agtgtcatac cagccgcgct ccatttcgcc gcgaatattc tcggcggtgg gcacttccag
    37621 tacaccaggc ttctccaccc gcagatagcc gttcattatg ttcggccctt tcagttgcag
    37681 gcgtccgccc tcttcgatac caggaaccga caacaggcgc gcatccattc ctggtagaat
    37741 acgccctacc gtaccgggtt tcgccgccat cggtacgttg atagaaacga caggcgcgca
    37801 ttcggtcaca ccgtagcctt caaggatgcg caggccaaat ttatcctgcc aaagctgttt
    37861 ggtactttct tgtagttttt ctgcgcctgc caccacatag cgtagacgat agaagtcata
    37921 cgggttggca aagcgcgcgt agtgaccgag gaaagtcgag gtaccgaaca acacggtgca
    37981 actgcggtca tacaccaact ccggcacaat gcggtaatgc agcgggcttg gataaaggaa
    38041 cacttctgca cctgtgagca gtggcgtaaa caggcctacc gtcagcccaa aggagtgaaa
    38101 cagcggtaac gccgacataa agcgatcgtt ggtggtgaag tcggcaatcg ttttaatctg
    38161 ctcaacgttc gccagaatgc ttttatggct atggacgacg cctttcggat ggccttcaga
    38221 accggaggta aagaggatca gcgcttcttc ttccggctgc tgttttaact gtgccagacg
    38281 cggcatcagc aaatgagcga aaatccacac tttgtcggca gtggtgacat ctgcttttaa
    38341 atcttccaga tagacccagc gcacctgagt aagttgctcc ggcagatgcc agagtttgcc
    38401 tttatcgaga aactgacggg aagtgaagat ggttttgatt tcagccgccg taatagcact
    38461 ggtcagccct tttaccccgg cggtgtagtt catcattgcg ggaatgcggc gacgggcgat
    38521 ggccccaaaa atcactgccg cactgatgcc tgcattgggc agcattaagc cgatgcgttc
    38581 gccttcaaca ctgtattttt caaggatgcg tccaacaaac agcgttttcg taagcaattt
    38641 gcgataggag tctggggtaa agttgacgtc ttcgacacat ttcttcccgg ctccgaagcg
    38701 gtacattgcg ctcagtaaag attcgtacag cgtttcacgc gggcgcaccg ccatacgcgc
    38761 ctccatcatt atttgatgca gcatttcgcc agcgattttg cgacggtcac gggcacgcgg
    38821 cgcatccggc atctccacct gcgttggtgg caaaatatgc agagtaattt gcgggaacaa
    38881 gcgacgttta accagacctt tcaggcggct gaagtgcgta agttccgccc cttcaatacg
    38941 cacaggaata accgttgcac cagacttcgc cgcgacaaat cccgcgccat cgtagatttt
    39001 catcagcgag ccagtggtgg tgatgcgtcc ttcagggaaa atcaccactg gtcggccctg
    39061 ttccaccaga cgtaccagat gtttaatcgc cataggttgc gtcgggtcga gaggaacaaa
    39121 gtcgataaat gatttcagcc aacgcatata ccactgttgg cttattgagg tgtaaacggc
    39181 aaataccgga cgtacgggta aaaacaatgc cagcagtatg ccatcaataa aagagacgtg
    39241 attaggcgtg attagaacgc gctcgccctt cagtgccttg gtgtcacccg taacgcgaac
    39301 gcgatacaaa acacggcaca aatttcgaaa aaagctaaaa agcattccaa ctccctttgc
    39361 tctgattcag taaaagcgaa tggagggaga ttacacgaga taaagaacgc gagcgacagt
    39421 aaattaggtg cgaaaaaaaa cctgcgcatc cgcgcaggtt ggtgcaagag acagggtacg
    39481 aagagcgtac cgaataatct caccaatcaa tacctctggg atcttgattg tggtctgcac
    39541 gacgactctt cgccagcgag aaaacgcaaa ggaatgaagg gaaatgcaac gaggtgtgta
    39601 aattgtcggt tactgttaca gattgatgac cggcaaaaaa aaacctgcgc atctgcgcag
    39661 gctggtgtaa ttcatgtgct caacccgaag ttgacttcac ctatcaatac ctctgggatc
    39721 accactttag caacctgaag ccaaacgcca ccagcggtca atcgcaacag cgtttcgcaa
    39781 agtgtaacca aaggtttgca atctcttttt ttgtcttact tatttgcgtt tggctcacat
    39841 tcccacaatg aaaacacgcc gccccttgaa ccaacgggcg ttttccgtaa cactgaaaga
    39901 atgtaagcgt ttacccacta aggtattttc atggcgacca taaaggatgt agcccgactg
    39961 gcaggcgttt cagtcgccac cgtttcccgc gtcattaata attcacccaa agccagcgaa
    40021 gcttcccgac tggctgtgca tagtgcaatg gagtctctta gctatcaccc gaacgccaac
    40081 gcccgtgcgc tggcgcagca gaccactgaa acgatcggtc tggtcgttgg tgatgtttcc
    40141 gatccgtttt tcggtgcaat ggtgaaagcg gtcgaacagg tggcttatca cactggtaat
    40201 tttttattga ttggcaacgg ttaccacaac gaacaaaaag agcgtcaggc cattgagcaa
    40261 ctgatccgcc atcgctgtgc tgcgctggtt gtccatgcca aaatgatccc ggatgccgat
    40321 ttagcctcat taatgaaaca aatgcccggt atggtgctga tcaaccgtat cctgcctggc
    40381 tttgaaaacc gttgtattgc tctggacgat cgttacggtg cctggctggc aacgcgtcat
    40441 ttaattcagc aaggtcatac ccgcattggt tatctgtgct ctaaccactc tatttctgac
    40501 gccgaagatc gtctgcaagg gtattacgat gcccttgctg aaagtggtat tccggccaat
    40561 gaccggctgg tgacatttgg cgaaccagac gaaagcggcg gcgaacaggc aatgaccgag
    40621 cttttgggac gaggcagaaa tttcactgcg gtagcctgtt ataacgattc aatggcggcg
    40681 ggcgcgatgg gcgtgctcaa tgataatggt attgatgtac cgggtgagat ttcgttaatt
    40741 ggctttgatg atgtgctggt gtcacgctat gtgcgtccgc gcctgaccac cgtgcgttac
    40801 ccaatcgtga cgatggcgac gcaggctgcc gaactggctt tggcgctggc ggataatcgc
    40861 cctctcccgg aaatcactaa tgtctttagt ccgacgctgg tacgtcgcca ttcagtgtca
    40921 actccgtcgc tggaggcaag tcatcatgca accagcgact aaccgcagtt aaagcaattc
    40981 cagcgccagt aattcttcaa tggtctggcg acggcgaatc aaccgcgcct gaccattatc
    41041 aaacagaact tctggtaaca gcggacggct gttgtagttg gatgacattg acgcgccata
    41101 tgcccctgta tcatgcagta ccagataatc acccgccttc acttccggca aggcgcgggt
    41161 ttcgacattt cccccttcct gctgggtaaa gacatcgccc gattcacata acggcccggc
    41221 gacgacggtt tccaccgttg gcgcgtgttc cagagaacga ccatcagctg ccagggcact
    41281 gatatggtgg taactaccgt acattgccgg gcgcatcaga tcgttgaacc cggcatcaac
    41341 cagaacaaag tggcggctac ccatttgttt gacgctccgc acttgagtaa ttaatacgcc
    41401 agcctgcgct accagaaagc gacccggttc aatttccagt ttcacaggat ggcccaaatg
    41461 gcgggcgatt tgctcacgcg cggcattcca cagaccataa taatgttcgg tatcaaccgc
    41521 ctcttcaccc tgttgataag gaatagaaag cccaccgccc gcagaaatag cctgtaaatc
    41581 ctgaccgaat tcgaggactt gacgcaccat agcaccacat acctgttcca gatgggcata
    41641 atcgacgcca gaaccaatgt gcatgtgaat gccgaccagc tgtagatgat gacgttgtat
    41701 cacgtccagt gcggcgggca gatcggtgta ccagataccg tgcttgctgt tttcgccacc
    41761 ggtattggtt ttttggctat gcccgtgacc aaaccccgga ttaacacgca gccatacccg
    41821 atgccctggc gaaacctgcc ccagttggtc gagcatatca acagaacccg cattcaccgg
    41881 aatttgcaat tcactgacgc gttcaagcgt cgcctgatcg ataacatctg ccgtaaaaac
    41941 aatatcatca gggtgcgttt gcggattgta acccgccgcc agtgcacgct ctatttcacc
    42001 taacgagacg gaatccactt ttacgccctg ctcacgcatt aagcgcaaaa tatgaatatt
    42061 ggaacaggct ttctgtgcaa agcgcaccac atcaaactgt ttcagcgccg caatctgccg
    42121 acgaataatt tgcgcatcgt agacccacac cgggcagcca aattctgcgg gcaaacgcag
    42181 cagattttcg gcggtgagat cggtatcagt gctgaacagt gaatgtggca taacaaactc
    42241 cagataagtg cttttttatg attacgccac atcataaaaa gaataaaaaa tatcgattta
    42301 tgtcgagtct atgcaaaaat gatatggatt accggattgc gagagagcgc taatggccgc
    42361 cgttaactta cgtcatattg aaatttttca tgcggtaatg accgccggaa gcctgactga
    42421 ggcggcacac ctgctacaca cctcacagcc aaccgtcagc cgcgaactgg cgcgctttga
    42481 gaaggtgatc gggctgaaat tgtttgagcg catacgtgga cgattacatc ctaccgtgca
    42541 aggactgcgt ctgtttgaag aagtgcaacg atcctggtac ggactggatc gcattgtcag
    42601 tgccgcagaa agtctgcgcg agtttcgcca gggagaactg tctattgcct gcctgccggt
    42661 cttttcgcaa tcttttttac cgcagctcct gcaacccttt ctggcacgtt atcccgatgt
    42721 cagcttaaat atcgtgcccc aggaatcacc gctacttgaa gagtggctct cggcccagcg
    42781 tcatgattta ggactcactg aaacgctcca tacgcctgcg ggaacagaac gtaccgaatt
    42841 actctcttta gatgaagtgt gtgtgttacc tccgggccat ccgctggcgg taaaaaaggt
    42901 attaacgccg gatgattttc acggtgagaa ctacatcagc ctttcccgta ctgacagcta
    42961 tcgccagttg ctggatcaat tgtttactga gaatcaggtt aaacgacgca tgatcgtaga
    43021 aacccacagc gccgcgtcag tctgcgcaat ggtacgggcg ggggtaggcg tttcagtggt
    43081 taacccgctc accgcactgg attatgcggc aagcggttta gtggtgcggc ggttcagcat
    43141 tgcggttcca ttcaccgtca gcctgatccg ccccctgcac cgcccgtcat cagcgctggt
    43201 gcaggcgttt agtgagcatt tacaagcggg attaccgaaa ctggtcactt ctcttgacgc
    43261 tattttgtcg tcagctacga cagcataaaa gcgacagcat cctcggcatg gatcgccgcg
    43321 gtatcaaaca caggcagaac actgcgctct tctggcacca gtaaaccaat ttctgtgcag
    43381 ccaaaaatga cgccctgtgc gccctgttct gcaaggcgag caatcacttg cgcataataa
    43441 gcgcgtgacg cttcggtaaa ttgccccaga cacagttctt caaaaataat ctgattaatt
    43501 ttcgcccggt catccgcttc aggaataaga cagttgatgg aaaattgttc cgtcagccgc
    43561 ccgcgataaa aatcctgttc catggtgtaa cgtgtaccca gcagcgccac acgagtcatt
    43621 cctgccccgg taattgcacg tccagtggca tccgctatgt gtaagaaagg cagagagcaa
    43681 cgagactcaa tggcatccgc cactttgtgc atcgtattgg tgcataacac aataccttct
    43741 gcgcccgccc gctgtaagcc aagcgccgcc tcagccagaa tatccccggt tttgtcccac
    43801 tcaccgcgac gctggcactc ttctatttca tgaaaatcga cgctatgtag cagcacttgc
    43861 gcagagtgaa gcccaccaag ccgctgttta atgccttcat ttatcagacg atagtaagga
    43921 atagtggatt cccagctcat tcctcccagc aaaccaattg ttttcattcc tctctcctga
    43981 tgagtgttac cgcaacaagg ctgaataagg aacgaggcaa acgcctcaac ggccaggtgc
    44041 ctaatctcta ttaacgaaaa aagggccgga tgtacagcac atccggcccg tgaaatcaga
    44101 cgccgatatt tctcaacttt tcgcctgcca tcagtttgcg ctcgatatgt tccagcgtga
    44161 catttttggt ttccggaatg agccagaaag tgatgcccac aaacgcaatg ttcagcgcag
    44221 tgtagagcca gaacgtaccg gcagcgccaa tgctatcaag cagtgtcagg aaggtcgcgc
    44281 cgataatcat attcgacacc cagtttgtcg tcgttgagca ggtgatgcca aaatcgcggc
    44341 atttcagcgg ctgaatttca gagcacaaga tccacaccac tggcgcggcg ctcatcgcat
    44401 aaccggcaat acacatcatc gtcatgccaa cagagagcca ggacaagcca ctggaagccg
    44461 taccgttatc aaactgcatc aggcagtaac ccagcaccag agtgcctaac gccatcacgc
    44521 tgaaaccaat tttcagcgcc ggcttacgcc ctgctttatc taccgtaaag accgcaatga
    44581 aggtagcgaa cataaaggtc agccccacga ccagagtcgc aatcatctgt tgttctgtgg
    44641 tcgtaaagcc cgccattttg aagatacgtg gcgcgtagta catgatgatg ttcataccgg
    44701 taaactgctg catcgcctgc aacaacatac cgagaaatac agcacgacgg acgttacggt
    44761 tgatcttaaa cagtgcccaa ccgccctgtt ttaacttcag gctttcgcga atttcgttga
    44821 gttcttctcg cgctttttcc gacgtatcgc gcagcatacg caatacttct tccgcctcaa
    44881 tatgacgccc cttttccgcc agccagcgcg ggctatttgg caggaagacc accagaataa
    44941 tcagcagaac tgctggtaaa gcaagaaccc ccaacattgc gcgccagtta ccgctataac
    45001 tgaacgctgt atcggataaa aacgccagca cgatgccgag agtgaccatc aactggtaca
    45061 tgctgatcat cttaccgcga acgttttcac ttgccatttc agaaagatat agaggagcgg
    45121 tgtaagacgc gatcccgaca gcaatgccca acaccacacg agcggcgatt aacatctcta
    45181 cgctggtcgc aaaagcggac cctatcgaac cgagtacaaa caggatggcc cccgccatca
    45241 ggctgtattt acgccccagg cggaacgaca gccaaccatt aaacagcgca ccaattgctg
    45301 caccgagcat catgctactg accacccatt cctgcaaacg actggtcagc acaaagtgat
    45361 cggtaatgaa cggcaacgct ccggcgatta cgccgatatc aagaccaaat aacaatcctg
    45421 cgaccgcagc agctaccgaa acaaacatat tcatacgccg cgtatcccgc agaggacgtg
    45481 gcgttaaagc agattccgta ttgatagtaa ccattttttc ctgccagcag agagtaagac
    45541 atagtgaaaa aatacgtgaa caattcacac aggtgtcagg tcggaaatag cataaatatg
    45601 gattaaattg ctacgacatg tcgttatgtg atggatattc caattttcaa attaagttga
    45661 attattgaga ttattattaa ccacctaatt ttaaagcaga taaaattcat aaagttcatc
    45721 aattgataat tgatatggat tatttcataa ccatgatatg gattatgatg atctacaggt
    45781 ataaaaaacc ctgccatgcg acagggtcat aaaagtaaga ggaatgaatt aacgcgccag
    45841 ccaaccgcca tccacggcaa tggtataacc attcacataa tctgaagcgc tggaggcaag
    45901 gaacaccacc ggccccatca ggtcactcgg cagtccccaa cggccagctg gaatgcggtc
    45961 gagaatttcc gcgctacgtt gttcatctgc ccgcagttgt tgagtattgt tggtcgccat
    46021 gtaacccgga gctatcgcat taacattaat gttgtgttta gcccattcgt tcgccatcaa
    46081 tcgcgtcacg cccatcacac cgctttttga tgcggtataa gaaggcacac ggatcccgcc
    46141 ctggaaggag agcattgacg cgatattgat aatcttgccg ccattgcctt gcgcgataaa
    46201 gtgtttcgcc gctgcctgag acatgaagaa tacgctcttg atattcaggt tcatgacatc
    46261 gtcccagtct ttttcgctga attcgagagc gtcttcgcgg cgaatcaatc cggcgttatt
    46321 caccaggata tcaatatgac caaactccgc taccgcgcga tccagcagtg ctggaatgcc
    46381 atcaatcttt cgcagatcgg cggtcaggct taaaaaacga cgccccagcg ccgtgacctg
    46441 cttgatggtt tcagtcggtt caacgatgtt aatgccaaca atgtcacagc ccgcttgcgc
    46501 cagccccaac gccatcccct ggcccagccc agtatcacaa ccagtgacga ccgcaacttt
    46561 accttcgaga gaaaatgcac ttaaaatcat aacaatacct tattcgttta tgcccacaac
    46621 tagcgcaaat ctttaacggc cacatggtcc atatcatcaa aaacctggtt ttcaccgacc
    46681 atgccccaga taaaggtata agctttggtt ccgacgccgg aatggatcga ccagctcggg
    46741 gagatcaccg cctgctcgtt atgcatcaca atgtgacgcg tttcttgcgg ttgccccatc
    46801 atgtggaaaa cgcaggcgtc atcatccata ttgaaataga aataaacttc catccggcgc
    46861 tcgtgggtgt gacacggcat ggtgttccac aagttacctg gagccagctc cgtcagcccc
    46921 atactcaatt ggcaggtttc cagcacatcc gggacaaaat atttgttaat cgtgcgacgg
    46981 ttactggtga ggttatcgcc taacgtgact ggagatactt cgtccggtgt gacttttttg
    47041 gtgggatacg tcgtatgcgc gggtgcgcaa ttgtaataaa acttcgccgg agtggcggta
    47101 tcaatactgg caaagacaac ttcttttgca cctttaccaa catacagggc gtcgcggtga
    47161 ccgatttcat agcattgacc atcgacagta atcgtaccgg caccgccaat attgataaca
    47221 cctaactcgc gacgttcaag gaaatagctt acgccgagtt gtttaccaac ttccccgcca
    47281 acggaaaccg ttttagttac cggcataatg ccgccaacaa taatacggtc aatgtggctg
    47341 taaaccatgg tgtactcatc ggcgacaaat accttttcaa ccaaaaattc attgcgcagc
    47401 ccctgggtat ccagcgtttt tgcgtgcgcg ctgtggatgc tctgtcttac gtccacatca
    47461 acctccgata atcagtgaag cgtgaaaata gaaaacaata ataaaacact gtttcgtttt
    47521 ctctatgagg ggatgatatg cccatgggat agggttttca attaaaaata aaacaatgtt
    47581 tcattttcaa gttaaggatt aaaaaaagtg cagtgtcgat cacgaatatg tcatgagaat
    47641 ggaaaaatca gggagccctg aaaaggtatg tcgactcacc agccatcatt attcaacaga
    47701 ttaatgacgg cagatattta tcggtaagga ggtaatgcag agctactcgt cacgttcaat
    47761 ggtcaatgcc acaccctggc ctccgccgat acaaagcgtt gccagtcctt tgcgggcatt
    47821 acgtttcacc atttcatgaa caagagaaac caggattcgg caaccggaag cgcctatcgg
    47881 gtgaccgagt gcgatcgcac caccattaac attgacccga cgctcatccc attcaagcat
    47941 cttgccaacc gaaagcgcct gtgcagcaaa cgcttcatta gcctcgataa gatcgacatc
    48001 agccaactgc cagccaacac gctccaggca acggcgggtc gcatacaccg gcgcaattcc
    48061 catcaatgcc ggatccacac caacgctggc aaatgcgcgg atgcgggcca gcacgggtaa
    48121 attcaacgct cgtgctttgg cttcgctcat catcattact gcagctgccc catcgtttat
    48181 ggatgatgca ttacccgctg tcacagaacc gagactatca aatgaaggat ttaaacgggc
    48241 taagccttct gcgctggtgt cagtgcgtgg ctgttcatcg gtatcaacaa ccaacgtctg
    48301 accgttactt tgggttatta ccgggacgat ctcatcttta aatcgtccgg cgtcaatcgc
    48361 cgctcgcgct ttttgttgcg agctaagtgc gtaagcatcc tgcaactgac ggctgatgcc
    48421 atattcgcga gccagatttt cggcggtgac accaatatga taatcattga aggcatccca
    48481 caacccatca tgcacaagac tatcaaccaa ctggctattg ccaagctgtg cgccggtgcg
    48541 gctatcagtc agaacatgtg gtgcgcggct catgttttcc tggccaccgg cgatgacaat
    48601 atcagcctcg ccacactgta tcgcctgagt agccagatgc agtgctttaa gcccggaacc
    48661 acaaacgtca ttaatagtga ttgcagaaac gctattagga agaccacctt taatagccga
    48721 ttgtcttgcc ggattctgcc ctgcccctgc agtcaacacc tgaccaagaa tcacttcatc
    48781 caccgcatat gcaggaacgc cggtacgttc tattaacgct ttgacgacca ggctgccaag
    48841 ttccacggcg gaatgacccg ctaacgcacc acgaaagcag ccgataggtg tccgtaacgc
    48901 cccgacaatc acaacgtctt tcatcacaac ctcgcaccaa ttaacagtgc aatagtaaat
    48961 gattgttaat tacagttatc ttaattgttt aaaaaaagtg accattatca caaaggaaat
    49021 acgcctgagt agtagtcaga gacataactg gcacgtaagg tttgcaacca ctaacccacc
    49081 aatagagagg tagataaggc gttaatctcc catacttaac ctggtttatg gtaaattgcc
    49141 ctccattttg tttaatttgt agatgatacg ttcagataat gtctaatatt tggtcaaaag
    49201 aagaaactct gtggagtttc gcactctacg gcacagccgt tggtgcaggc acgctcttcc
    49261 ttcctattca gttaggttcg gcgggggctg tggtcctgtt tattactgct ctggtcgcct
    49321 ggcctttaac atattggcca cataaagcct tatgccagtt catcctctca tcgaaaacat
    49381 cagcaggtga agggataacg ggcgcggtaa cacactacta tggcaagaag attggtaatc
    49441 tgattaccac gctgtacttc atcgcctttt ttgtcgtcgt gttgatatat gcagtggcaa
    49501 ttaccaactc acttacggaa cagctggcaa agcatatggt tattgatctt cgcatccgta
    49561 tgctagtgag tctgggggtt gtattaatcc tgaatctcat ttttctgatg ggacgccatg
    49621 ccactattcg ggtaatggga tttttggtat tcccattgat tgcctatttc ttatttcttt
    49681 ctatttacct ggtcggtagt tggcaacctg atctattaac aacccaggta gagttcaatc
    49741 agaataccct tcaccagata tggatatcga ttcccgtgat ggttttcgct tttagccata
    49801 cgcccattat ttctacgttt gccatagaca gacgtgaaaa atatggcgaa catgctatgg
    49861 ataaatgcaa aaaaattatg aaagtcgctt atctcatcat ctgcataagt gtattgttct
    49921 ttgtctttag ctgcctgctt tctattccac cttcgtatat tgaagcggct aaagaagaag
    49981 gggttaccat tttatcggcg ctttctatgc tgccgaacgc cccagcatgg ttgtcaattt
    50041 ccgggattat tgtcgcagta gttgcgatgt cgaaatcatt cctgggtacg tactttggcg
    50101 ttattgaagg tgccacagag gtcgtcaaaa caacattaca gcaggttggt gtaaagaaaa
    50161 gtcgtgcatt taaccgcgca ctatcaatta tgttggtatc gctgattacc ttcattgttt
    50221 gttgcattaa cccgaacgcg atttcgatga tttacgcgat cagcggcccg ctcattgcca
    50281 tgatactttt catcatgcct acgctgtcaa cgtatctcat cccggcgctt aaaccctggc
    50341 gttccatcgg aaatctgatt accctgatcg tgggtatcct gtgcgtatcg gtaatgttct
    50401 ttagctaata tccgttgtgg atggttcaaa attgcttcaa ttttgaacca tcccagtttt
    50461 cataatgttc atttgttatt attccgctct atcacttctc tcgtaatatt atataattat
    50521 cagccagtta aacacacaaa gagttctgaa catcttaaat aagactattt aagatacatg
    50581 acgattgcat tgcgtaaacg ctttttattt acaaaaaaat ggggaagtat tacggcgatt
    50641 gcgaaaagtc tgaagcgctt gaattaagat aatatagaaa atcagataca acaaaaatgg
    50701 caggtagatg atgtgaagat aaattggagc gggcgaaggg aatcgaaccc tcgtatagag
    50761 cttgggaagc tctcgttcta ccattgaact acgcccgctt cgagatgcgt aaggcattat
    50821 aaaccttacg ctctccttag caagtaccac gctgctgact gctgattaat tcgccatcag
    50881 cattttggct tgctgccctg aggcggcaag taacgtagcg gatcaattgc cgttgcacgg
    50941 taacgaatct ggaaatgcag gcgaacagat gccgcatcag tgctccccat agtggcgatt
    51001 ttttgcccag ccttcacgct ttgcccatta tttaccagca tcgtgtcatt atgagcgtaa
    51061 gccgtaatgt aatcttcact gtgtttaatc atgatgagat taccgtagcc acgcagctgg
    51121 ttgcccacat acaccacctt tcctgcaccc gcggcgtaaa taggtgtacc tcgtggagct
    51181 gagatatcaa tccctttatt gccgccatct gctgtcgaat acggcatgat aactttccct
    51241 gtcgttggcc ataaccaaca acgttgccct actggcggcc aggaagattt cggtaccgct
    51301 gatgacggtg taaccgatgc ggttttggtc gtggatttgg cggttgattt acgtgtacta
    51361 ctgctacttt tcgccccacc cagttttagt ttctgaccta cttcaatggt gtaagggggg
    51421 gaaatgccgt tcagtcgcgc cagttctttt acgctggttc ccgtggtgcg cgaaatacga
    51481 tatagcgtat ccccccgttt cacggtgtaa acggagccgg aatacgttcc tgtatcggat
    51541 gatttgctac ccgaacagcc cgccaaaagc agtccaaccg ataacaacat cacgataccc
    51601 agagattttt tattcaggcg tcccgcactc aaaatctttc ctcgcttaaa aaacaagacg
    51661 ccatatcata gcagccagcc tcttgatacc caatctcttg cttctggaaa aacgatgtaa
    51721 tagagaaaga ggttaatttc atttggcaaa gggaagtatc atcagcaaaa tatttgctgt
    51781 agtggtatcg aatttcctga cttttaccct atttcccacc ttgatgcgta ataatcctaa
    51841 tttatcacat tgattttatc gccactcata ttgatacgta tcactgtccc tattcagagt
    51901 cctgtttcgt atcatatctg tgttttttta acgtcatcac acttccttcc tcccctcacg
    51961 catatagtcg tttctggcgt aattcttgcc tgctaagact aaatctttgc cataagaacc
    52021 aaatgttcaa accgagggga tttctatgga agcgcgggaa gcaaccgcta cgggtgaatc
    52081 atgcatgcgc gtcgatgcca ttgctaaggt caccgggcgg gcacgatata ctgacgatta
    52141 tgttatggcg ggcatgtgtt acgcgaaata tgtacgtagc cctatcgcac atggttatgc
    52201 cgtaagtatt aatgatgaac aagccaggag tttgccgggc gtcctggcga tttttacctg
    52261 ggaagatgtg ccagaaatcc cattcgccac ggcagggcat gcctggacac ttgacgaaaa
    52321 caagcgcgat actgccgatc gtgccctgct aacgcgtcat gttcgtcatc atggtgacgc
    52381 cgttgccatc gtcgtagccc gcgatgaact cacggcagaa aaagcggtgc aattggtcag
    52441 cattgagtgg caagaattac ccgttatcac ctcgtcagaa gcggcgctgg cagaagacgc
    52501 tgcaccaatc cataacggtg gcaatttact gaaacaaagc acgatgtcga cgggtaatgt
    52561 ccaacaaaca atcgatgccg ccgactacca ggtacagggg cactatcaga cgcccgttat
    52621 tcaacattgt catatggaaa gcgtgacatc gctggcatgg atggaggatg actcgcgaat
    52681 taccatcgtt tccagcaccc agatcccgca cattgttcgc cgcgtggttg gtcaggcgct
    52741 ggatattccc tggtcatgcg tacgagtcat caaaccgttt atcggtggcg gttttggtaa
    52801 taaacaggat gtactggaag agccaatggc ggcattcctg acaagcaaac ttggcggcat
    52861 tccggtgaaa gtttctctta gccgtgaaga gtgtttcctc gcaacccgta cccgccacgc
    52921 ttttactatt gacgggcaaa tgggcgtgaa ccgcgacgga acattgaaag gttatagtct
    52981 ggatgttctg tctaacaccg gcgcttatgc atctcacggg cactccattg cttctgctgg
    53041 ggggaataaa gtcgcttacc tttatcctcg ttgtgcctac gcttacagtt caaagacctg
    53101 ctataccaac ctcccctcgg ctggtgcgat gcgtggttat ggcgcgccac aagtcgtatt
    53161 tgccgttgag tctatgcttg atgatgccgc gacagcgtta ggtattgatc ctgttgaaat
    53221 tcgtttacgc aacgccgccc gcgaaggaga tgctaatccg ctcacgggaa aacgtattta
    53281 cagcgcaggg ttgccggagt gtcttgaaaa aggccggaaa atctttgaat gggaaaaacg
    53341 ccgtgcagag tgccagaacc agcaaggcaa tttacgtcgt ggcgttggcg tcgcctgttt
    53401 tagctacacc tctaacacct ggcctgtcgg cgtagaaata gcaggcgcgc gcctgttgat
    53461 gaatcaggat ggaaccatca acgtgcaaag cggcgcgacg gaaatcggcc agggtgccga
    53521 caccgtgttc tcgcaaatgg tggcagaaac cgtgggagtt ccggtcagcg atgtccgcgt
    53581 aatttcgaca caagacaccg acgttacacc attcgacccc ggcgcatttg cctcacgtca
    53641 gagctatgtt gccgcgcctg cgctgcgcag tgcggcactg ttattaaaag agaaaatcat
    53701 cgctcacgcc gcagtcatgc tacatcagtc agcgatgaat ctgaccctga taaaaggcca
    53761 tatcgtgctg gttgaacgac cggaagagcc gttaatgtcg ttaaaagatt tggcgatgga
    53821 cgctttctac caccctgaac gcggcgggca gctctctgcc gaaagctcca tcaaaaccac
    53881 cactaaccca ccggcgtttg gctgtacctt tgttgatctg acggtcgata ttgcactgtg
    53941 taaagtaacc atcaaccgca tcctcaacgt tcatgattcg ggccatattc ttaatccgct
    54001 gctggcagaa ggtcaggtac acggcggaat ggggatgggc attggctggg cgctatttga
    54061 agagatgatc atcgatgcga aaagcggcgt ggtccgtaac cccaatctgc tggattacaa
    54121 aatgccgacc atgccggatc tgccacaact ggaaagcgcg ttcgtcgaaa tcaatgagcc
    54181 gcaatccgca tacggacata agtcactggg tgagccaccc ataattcctg tagccgctgc
    54241 tattcgtaac gcggtgaaga tggctaccgg tgttgcaatc aatacactgc cgctaacgcc
    54301 aaaacgatta tatgaagaat tccatctggc aggattgatt tgaggataac atcatgtttg
    54361 attttgcttc ttaccatcgc gcagcaaccc ttgccgatgc catcaacctg ctgactgaca
    54421 acccgcaggc caaactgctc gccggtggca ctgacgtact gatacagctt caccatcaca
    54481 atgaccgtta tcgccatatt gttgatattc ataatctggc ggagctgcgg ggaattacgc
    54541 tggcggaaga tggcgcgcta cgtatcggct ctgcaacgac atttacccag ctcattgaag
    54601 atcctgtaac tcaacgtcat ctcccggcgt tatgtgctgc ggctgcatca atcgccgggc
    54661 cgcagatccg taatgtcgcc acctacggcg gaaatatttg caacggtgcc accagcgcag
    54721 attctgccac gccaacgcta atttatgacg cgaaactgga gatccactcc ccgcgcggtg
    54781 ttcgtttcgt cccgattaat ggctttcaca ccgggccggg caaagtgtct cttgagcatg
    54841 acgaaatcct tgtcgccttt cattttccgc cacagccgaa agaacacgcg ggcagcgcgc
    54901 attttaaata tgccatgcgc gacgcaatgg atatttcaac aattggctgc gccgcacatt
    54961 gccgactgga taacggcaat ttcagcgaat tacgcctggc atttggtgtt gccgcgccaa
    55021 cgccgattcg ctgccaacat gccgaacaga ctgcacaaaa tgcgccatta aacctgcaaa
    55081 cgctggaagc catcagcgaa tcagtcctgc aagatgtcgc cccgcgttcg tcatggcggg
    55141 ccagtaaaga gtttcgtctg catctcatcc agacgatgac caaaaaagtg attagcgaag
    55201 ccgtcgccgc ggcggggggg aaattgcaat gaatcacagc gaaacaatta ccatcgaatg
    55261 caccattaac gggatgcctt ttcagcttca cgccgcacca ggcacgccgc tctcggaatt
    55321 actccgcgaa caaggactgc taagtgtcaa acaagggtgc tgcgtgggtg aatgtggtgc
    55381 ctgtacggtg ctggtcgacg gcactgcgat agacagttgc ttattccttg cggcctgggc
    55441 tgaaggaaaa gagatccgca cgctggaagg tgaagcgaaa ggcggtaaac tttctcatgt
    55501 ccaactggct tatgcgaaat ctggtgcagt gcaatgcggg ttttgtacgc cgggcctgat
    55561 tatggctacc acggcaatgc tggcgaaacc acgcgagaag ccattaacca ttacggaaat
    55621 tcgtcgtgga ctggcgggaa atctttgtcg ctgcacgggg tatcagatga ttgtaaatac
    55681 agttctggat tgcgagaaaa caaagtaaaa gatatccggc ctgaattcag gccggattct
    55741 cagaggttat gtgtttaaca actcatattt cttaatcttg cgatagagcg tagcaatgcc
    55801 gatgcccagt tcatcagcaa cttccttctt gctgttatga cgtgaaagcg cctcgcggat
    55861 catttgcttt tccatctctt ccagcgccgt gccgcccgca tcatcgagtg acaggtgcgc
    55921 ctcactggcc tctgttacat cactttgctc cgttgtgcca ttattcagca gatttggcgg
    55981 caatagcgtg ctgtcgataa cttcacctga aggaacaacg ttaaccagat attccatcaa
    56041 attgcttaac tcgcgcaggt ttccgggcca acgatgctta cgcaatattt cgacgacatc
    56101 aggagcaatg ccaggataaa ccgatcccag acgacgggta tgcagatgta aaaagtaatg
    56161 cactagtaat tcaatatctt cctgacgttc acgcagcggt ggaagagtta tcgggataac
    56221 attaagtcgg tagaagagat cttcgcggaa tttaccttcg gcaatgaact gggccaaatt
    56281 ctgattagtt gcagaaatga tgcggatgtc gacttgtatt gggctactgg caccaatcgg
    56341 cagaatttca cgcgcctcaa tagcgcgcag taatttagcc tgcaacatta atggcatatc
    56401 accaatttca tcgagaaaca gcgtgcccgt attcgccgcc tgaatcaacc ctgttttacc
    56461 gttggcagaa gcgccagtaa atgcgccttt aacataaccg aacagttcgc tctccagaag
    56521 ctgttccgga atcgcggcac agttgatagc aataaagggt ttattccgtc ttccgctcaa
    56581 cttatggatt gcacgggcga cgacttcttt acccgtgccg ctttcaccaa ccaccataac
    56641 gctggatggg ctgggtgcaa tacggctaat gagtcgtttt aattgccgca taacacggca
    56701 ctcgccaacc aattgttcaa tatgcggttc atcaggtgca tttgctacag aaaaactggt
    56761 atgcgattgg tgaaacgcca ttaaaaatag ttgtcggccc tggatgttat gcaactgacc
    56821 aatgattaat tcacttttat catcccacga aacaatatgt tgcatatgac catgggtaaa
    56881 attactctca aatgttaatg gtctgaaacg aacaggtttt ccaataatat tattttgtac
    56941 aacaccgagt gtttttaaag ctgtctgatt aacaaactga acccgattat cagcatcaac
    57001 cactaacacg ccctgatcca tattatcgat catggtcgcg aatattttac tgatgttatc
    57061 tcctggtccc tgatcctcca gaagtttaga aacaaaaatg gtggatatat ggcgaacgta
    57121 atcggaaaat tcgcgtaaat tatcactgat atgttcttgt tgctcgtggg taacggcaat
    57181 caaacttatc accccaacac aacgatcctg taaaatgact ggcgtaccca gaaatgcttt
    57241 ttcgcggcaa ttttctttac tatcgcaacc ttcacaaagg ggatcgaagc gagactgtgt
    57301 cacaactttt tcagttttcg tttccaggac gtggcggagc agacgtgagt tgccgctcaa
    57361 ctggcggcca agaaacttcc catacgcgcc cgttccggcg acgcgacaca agttttcatc
    57421 aacgatctca acctcaagct gcaaaacgct ggcaagcatt ctggcaaaac gctgaattgt
    57481 tggttgaatt tgcatcaata ctgactgcgt agtcgcaagc tccatagctt taccttccag
    57541 acttacttaa aagtcgatca ttgaagacgt tgatggttca cagatcatga tgatattaac
    57601 tcaggcgaaa ttggctttga taaaaacata agatttttat cactttctaa taaaattatg
    57661 gaagagatat cacatttcta tatcaatatg agaattacag cggcaagttt atcaaactga
    57721 agagagatag cctgcctctt tatcttattt ctgatactta gcagcaaata aataacgtaa
    57781 taaaaaaagc caaacgtttt cgtattttac aaacaaccgg aaactggcat caatatgtga
    57841 tcaaccccac acattatccg tcaaattagc ctttcgcagc cgcgtggata attctggcac
    57901 acttattgtt agtccgaggt atagctgtga aaacaccaat cactttggca cgtcacagtg
    57961 aaataaacca ctttgcctgt cattccacta tcgggacttt atgatgaaaa ctgttaatga
    58021 gctgattaag gatatcaatt cgctgacctc tcacctgcat gaaaaagatt ttttgttaac
    58081 gtgggaacag acgccagacg aactgaaaca agtactggac gttgccgccg cgttaaaagc
    58141 actgcgtgct gaaaacatct caaccaaagt ctttaatagt ggattaggta tttccgtatt
    58201 ccgcgacaat tccacccgta cccgcttctc ttatgcttcc gcgcttaacc tgctcggcct
    58261 tgcacaacaa gatcttgacg aaggtaaatc acaaatcgct cacggcgaaa ccgtgcgtga
    58321 aaccgccaat atgatctcct tctgcgctga cgctatcggt attcgcgacg atatgtatct
    58381 gggcgcaggc aacgcctata tgcgtgaagt tggcgctgca cttgatgacg gttacaagca
    58441 gggtgtgctg ccgcagcgtc cggctttagt gaacctgcaa tgcgatattg accacccgac
    58501 tcaatcaatg gctgatctgg catggttacg tgaacacttt ggttcactgg aaaacctgaa
    58561 aggtaaaaaa atcgccatga cctgggccta ctccccaagc tatggcaaac cgctctctgt
    58621 accacaaggc atcatcggtc tgatgacccg cttcggtatg gatgtcaccc tggcccatcc
    58681 ggaaggctac gacctgatcc cggatgtcgt tgaagttgct aaaaacaatg ctaaagcctc
    58741 cggtggtagc ttccgtcagg tcaccagcat ggaagaagcc ttcaaagacg cagacatcgt
    58801 ttatccgaag tcctgggcac cttacaaagt gatggaagag cgtactgaac tgctgcgtgc
    58861 gaacgatcac gaaggactga aagcgctgga aaaacagtgt ctggcacaga acgcacagca
    58921 caaagactgg cattgtaccg aagagatgat ggagctgacc cgtgatggcg aagccctgta
    58981 catgcactgc ctgccagctg atatcagcgg cgtatcctgc aaagaaggtg aagtgactga
    59041 aggcgtattc gaaaaatacc gtatcgctac ctacaaagaa gccagctgga agccttatat
    59101 catcgccgcg atgatcctgt cccgtaaata cgccaaacca ggtgcactgc tcgagcaact
    59161 gctgaaagaa gcgcaagaac gcgtgaaata acccctcggg ccgatcagct ggtcggccct
    59221 ctatttccag aggccaaaag gataggatat gtccgttttc tcattaaaga ttgatatcgc
    59281 cgataacaaa tttttcaacg gcgaaacatc accgcttttt tcgcaaagcc aggcaaaact
    59341 ggcacgccag ttccaccaga aaattgctgg ttatcgccca acaccgcttt gtgcgctgga
    59401 cgatctcgca aacctgtttg gtgtaaagaa aattctcgtt aaggacgaat caaaacgctt
    59461 cggtctgaac gccttcaaaa tgctcggcgg cgcatacgcc atcgctcaat tattgtgtga
    59521 aaaatatcat cttgatatcg aaacgctatc atttgagcac ctgaaaaatg ccattggcga
    59581 aaaaatgact ttcgcgacca ccaccgacgg caaccacggg cgcggtgtgg catgggccgc
    59641 tcagcaactc ggacagaatg cggtgattta catgccgaaa ggttctgctc aggaacgcgt
    59701 tgacgccatt ctaaacctcg gtgccgagtg catcgtcacg gatatgaact atgacgatac
    59761 cgttcgcctg accatgcaac acgcgcagca gcacggctgg gaagtggtac aggacacggc
    59821 atgggaaggt tacaccaaaa tcccaacctg gatcatgcaa ggctacgcaa cactggcgga
    59881 tgaagccgtc gagcaaatgc gtgaaatggg cgtaaccccg acacacgttc tgctgcaagc
    59941 aggtgtcggt gcaatggccg gtggtgtgct gggttatctg gtcgacgtct atagcccgca
    60001 aaatctgcac agcattattg ttgaacctga caaagctgac tgtatttatc gctccggcgt
    60061 caaaggcgac atcgtcaacg ttggcggtga tatggccacc atcatggcgg gcctggcctg
    60121 cggcgaacct aacccgctgg gctgggaaat cctacgtaac tgcgccaccc aattcatctc
    60181 ctgccaggac agcgttgccg cattaggtat gcgcgtgctg ggtaatccgt acggcaacga
    60241 cccgcgcatc atctccggtg aatccggcgc tgtcggtttg ggcgttctcg cagcggttca
    60301 ttatcacccg caacgtcaaa gcctgatgga aaaactggcg ctgaacaaag atgccgtggt
    60361 gctggttatc agcactgaag gcgacaccga cgtgaagcac taccgcgaag ttgtctggga
    60421 aggcaaacac gctgtagcac cttaatcacc ctattggaac tgctccctgc aaaacgggga
    60481 gtaaaaaatc tggagaaaaa taatggctaa gaatattcca ttcaaactga ttcttgaaaa
    60541 agcaaaagat taccaggcag acatgactcg cttcctgcgc gatatggttg ctattcccag
    60601 tgaaagctgc gacgagaaac gcgtagtaca tcgtattaaa gaagagatgg aaaaagtcgg
    60661 cttcgataaa gttgaaatcg acccaatggg caacgttctc ggttatatcg gccacggccc
    60721 gcgtctggtg gcaatggacg ctcatatcga tacagtcggc attggcaaca tcaaaaactg
    60781 ggacttcgat ccgtatgaag gcatggaaac cgacgagctg atcggtggtc gtggtacttc
    60841 cgaccaggaa ggcggcatgg cgtctatggt atatgccggt aaaatcatta aagatctcgg
    60901 tctggaagat gaatataccc tgctggttac cggtactgtg caggaagaag actgcgacgg
    60961 cctgtgctgg cagtacatta ttgaacaatc cggcattcgc ccggaatttg tggtcagtac
    61021 cgaaccaacc gactgccagg tataccgtgg tcaacgcggt cgtatggaaa ttcgtattga
    61081 tgttcagggt gttagctgcc acggttcggc accagaacgc ggtgataacg ccattttcaa
    61141 aatgggtccg attcttggcg aattacaaga actctcccaa cgtctgggtt atgacgaatt
    61201 cctcggcaaa ggcaccctca ccgtttctga aattttcttc acctccccaa gccgttgcgc
    61261 tgtcgcagac agctgcgcag tttcaatcga ccgtcgtctg acctggggcg aaacctggga
    61321 aggcgcgctg gacgagatcc gtgccctgcc tgcagtacaa aaagcgaatg ctgtcgtttc
    61381 tatgtacaac tacgaccgcc cgtcctggac tggcctggtt tacccaaccg aatgctactt
    61441 cccgacctgg aaagtggaag aagatcactt caccgttaaa gcactggtga atgcttatga
    61501 agggctgttt ggtaaagcgc ctgtcgttga taagtggacc ttctcgacta atggcgtatc
    61561 catcatgggt cgccacggca ttccggtcat cggttttggc cccggtaaag aaccggaagc
    61621 gcacgcgcca aacgaaaaaa cctggaaatc tcacctggta acctgtgccg ctatgtacgc
    61681 tgcaatccca ttaagctggc tggcaaccga ataattactc ttcacttatt cccctccggt
    61741 tcaccggagg gtttttggag tttgctatgc gcgtattgat aaaaaacggc attgttgtta
    61801 atgcagatgg acaggcgaag caggatttgc tgattgaaag cgggattgtt cgccagttgg
    61861 gtaccgatat ttcgccgcaa ctcccttgcg aagaaattga tgcctctggc tgttacgttt
    61921 tccctggcgg cgtggatgtc catacgcatt tcaatattga tgtcggcatc gcgcgcagtt
    61981 gtgatgattt ttttaccggt acccgcgcag ctgcgtgtgg cggtacaaca accattattg
    62041 accatatggg atttggccca aatggctgcc ggttacgcca tcaactggaa gtttatcgcg
    62101 gttatgccgc ccacaaagca gtcatcgact acagctttca cggtgtcatt caacatatta
    62161 atcacgctat cctcgacgaa attccgatga tggttgagga aggactgagc agttttaaac
    62221 tctatttaac ctatcaatat aaactcaacg atgatgaagt gttgcaggca ttacgccgct
    62281 tgcatgagtc cggcgcgctg accaccgtgc acccggaaaa tgacgcagct atcgccagca
    62341 agcgggcgga gtttatcgcc gcagggttaa ccgcgccgcg ttatcatgcc ttgagtcgac
    62401 ctctggaatg cgaagcggaa gccatcgccc gcatgattaa cctggcacaa attgccggta
    62461 acgccccgct ctatatcgtg cacctgtcta acggcttagg tctggattat ctgcgtcttg
    62521 cccgtgcgaa tcaccagcca gtctgggttg aaacctgccc acaatatctc ctgttggacg
    62581 aacgcagtta cgatacagaa gatggcatga agttcattct tagcccaccg ctgcgtaacg
    62641 tacgcgagca ggacaaactg tggtgtggca tcagcgatgg tgcgattgac gtggtggcaa
    62701 ccgatcactg caccttctcg atggctcaac gcctgcaaat ttctaaaggc gatttcagcc
    62761 gctgcccaaa tggcttaccc ggtgtggaga accgcatgca actgctgttc tccagtggcg
    62821 tgatgacggg gcgtatctca ccggagcgtt ttgttgagtt aaccagtgca atgcccgcca
    62881 ggctgtttgg cctgtggcca caaaaaggat tattagcgcc cggttccgat ggcgacgtgg
    62941 tgattataga cccacgtcag agccaacaaa ttcagcatcg ccatctccac gacaacgctg
    63001 actactcgcc atgggagggt tttacctgtc agggcgcgat tgtcagaacc ttatcccgtg
    63061 gtgaaacgat tttctgcgac ggcaccttta caggcaaagc cgggcgaggt cgtttcctgc
    63121 gacgcaaacc gtttgtccct cccgtgctct aaccactgcc agggatctat acacaatcaa
    63181 gaatgatgag tgaggaaaaa tgagtaagaa aattgttctc gccctgggcg ggaatgcgct
    63241 gggcgatgac ctggccggac aaatgaaagc ggtaaaaatt acttctcagg caattgttga
    63301 tttaattgcc cagggacatg aggtcatcgt cactcatggc aacgggccac aggtgggcat
    63361 gattaaccag gcctttgaag ctgccgcaaa aactgaagcg cactcgccaa tgctgccgat
    63421 gtctgtctgt gttgccttaa gccagggtta tattggttac gatctacaaa acgccttaag
    63481 agaagaactg ctttctcgtg gcattaataa acctgtagca acgctggtta cccaggtcga
    63541 agtcgatgct aacgatccgg cattcctcaa cccgaccaag ccgattggtt cgttctttac
    63601 cgagcaagaa gcagagctac tgacaaaaca gggttacact ctgaaagaag atgcgggtcg
    63661 cggctatcgt cgtgtcgttg cttcgccaaa accggttgat atcattgaaa aagaaacggt
    63721 taaagctctg gtagatgccg gacaggtggt gatcaccgtt ggcggtggtg gtatccctgt
    63781 tattcgtgaa ggtaaccatc tgcgtggtgc cagcgcggtt atcgataaag actgggccag
    63841 tgcccgttta gcagaaatga tcgatgccga tatgctgatc attctgactg cggtagaaaa
    63901 agtggccatt aacttcggaa aagagaatga acagtggctc gatcgcctgt cattaagtga
    63961 tgctgaacgc tttatcgaag aaggtcattt tgcgaaaggt tctatgctgc ctaaagtgga
    64021 agctgccgcc tcgtttgctc gctctcgcgc aggtcgtgaa gcactgatta ccgtattgag
    64081 caaagcgaaa gaagggattg aaggcaaaac cggaacggtg atttgtcagt aatttaaagg
    64141 ccggatgggt aataccatcc ggccattttc atttaagcca cttccagcac ttcttttgtc
    64201 gctttaacgc cctgatgcat caacatcatt aacgcctcaa gtacgccgcc gccaatcgcc
    64261 cgggctttat cagaaacgct ggtgaaatca gccgtttcac cacgaggatc gatatcacca
    64321 attttaaaac caccgaccac ggccagtccg tcgttcaaca agccacgcac catccccgtc
    64381 aacggtgctt taatttcatg ctcaccaatc caggcaatga catcgccctc tttcaccaga
    64441 tcgcctaatt tcacgttgga tcgcataatg cctgcagcag gagcgcggat cactcgtcgg
    64501 gtggtatgcc ccataatatt gccgggaaca ccggtattct cctgcgcaca acctgagtaa
    64561 atcacctgac cgagccagtg cccgcgattt gtttcaatta ccgcatgaca atccttccct
    64621 gcagtaaagc ccggcccaag cgcgattgtt actggtgcca tatctgcccg cgttcccaaa
    64681 ttctgtttcg ccagaatagc gtccaccacg caaagcggtt tcagttcatc aagcaatgaa
    64741 caggtgggat ctaccatcac agggataaat ccgcgttcgg taagtttcat cgcttccgca
    64801 gagctggttg ccaggcgggc ggtgacgcct tcgaccgtca tttcgccatc gaacacggcc
    64861 tgggcaaacg ccacggtaca acgaatcact gtcggttttt ccacttccaa catgatcact
    64921 ttaaaacccg catgatacag acgtagcgct acaccactgg cgatatcccc cgcaccgcga
    64981 atcaccacca gctggtgtcc ggaaggatga gaaggcttca tcatcagccc acccggcgcg
    65041 ttatttttca cctgtaatat ttctgccagc acgctgatgg cgatctcctg cggcgtttcc
    65101 gcacctatgt tgtaaccaac gggcgcatgt aaacgggcaa tatgttcttc agccacgcct
    65161 ttctcacgca attggtgtag gaaaagctga accttgcggc gacttgccag caaccccagc
    65221 catgcaatgg gttgttcaat gagtttgtcg agggcttcac gatcctgatt attcgtggca
    65281 atcaggacaa aattatcagg gcgaatatcc agtgcttcca ctgccgcacc aaacgactca
    65341 gcatggagaa gcgtggttga tggtgggaat agttcaggat tgaggctttc gcgataaata
    65401 tcggcaacgg cgatatcaaa tcctaatagc gccgcactct gggctatcgc ccggttgaca
    65461 tgccccgcac caatcaacac cagacgtgga cgcataccat ggacgctgat aaatactgac
    65521 attgcacctc cacaatctga cccgacagca tccgcaccgt tacgagccat acgtccatgg
    65581 aataatcgcg gcttacgttc ctgcaatgcc tgaagcgact cttcaatcac cttccgctca
    65641 accattccgc caccaattgt accgacgata gaaccatcgg cgcgcactaa catttgtgca
    65701 gaatggcggg gggttgagcc tcggctatca acaatttgcg ccatcgcaaa cggacaattt
    65761 tgctcttcga gttttgcagc ctctgtgaaa atattcatac caacctcaat ggatatcctt
    65821 tcagtaaccc ggaatacccg ggccgctaat tcacaaatct gcgcgcgatt gcaggatgtt
    65881 cttgtatatc gcccagccag attgcctcta cgttgtgttg ttgcagcggt tgaaggagct
    65941 cgctttgcgc aatcgcattc tcacattgag aaaaacggtt aatgaaccag actcgccgac
    66001 aaccttgcgg tacgttttta aacgcgccct gagggtggcg aaccagcgca acgagatcgc
    66061 tcagttgcaa gggtgcatca ggtgttaacc cagtaatatc agcaaactgc gaccagcgat
    66121 ggacattttc tgtgctcact ttcgcaccca aaatatgtcc tcccatcaca gcaatcacgc
    66181 agcaactgct tttaggtatg caaggttcgt gctcatcagg cgcttttaac ggcattccac
    66241 gcgagccatc tgcctcaatg agaattacgt cacactctgg tcgttgtacc agtgcatcaa
    66301 tcgcttctgg cgtaaatccc tgcacttttc cctggttcgc tttccagcag tgaaaacaaa
    66361 atgaaatggg ggatataaaa gacgcatgag gaagcatggc gggatcacga cagaaaacca
    66421 cgggccagtg agatgttggc ataaacatat gtgtcgtcgt agtgattaat acacgcctgc
    66481 cactcgcctg gaacagttct gccagccaaa aaagcaagct ggttttcccc ccagcaccaa
    66541 caatagaaat cacagtggga cgtttctgcg cgcctaaatc aatgaataat gccgatgggt
    66601 caattatact tttcacgcgt ctttatggac ctctctggga taaattaccc tcaacgtaat
    66661 ccatcaggaa gtaacgcaat tatcaggcgt tattagctcc tgtaaataat ggaatcacta
    66721 tgtcagccat cgactgtata attaccgccg caggattatc atcaagaatg gggcaatgga
    66781 aaatgatgtt accctggcaa cagggaacaa ttcttgatac aagtatcaaa aatgcgttgc
    66841 agttttgtag ccgaattatt ttagtcaccg gctatcgtgg taatgaactg cacgaacgtt
    66901 atgcgaacca gagcaatatc actattatcc acaacccaga ttatgcgcag ggtttactga
    66961 catcagtaaa ggccgcagta cccgcggtgc aaacagaaca ttgttttctc acccacggag
    67021 atatgccaac cctcaccatc gatattttta gaaaaatctg gtcgttacga aatgatggcg
    67081 caatactgcc actccataat ggcatccccg gccatccgat tttagtgtca aaaccatgcc
    67141 tgatgcaggc aatccagcgc cccaatgtca ccaatatgcg tcaggcactc cttatgggag
    67201 aacattattc cgtcgaaata gaaaatgcag aaataatttt agatattgat actccggacg
    67261 actttattac agcgaagaaa aggtatactg aaatttagaa aacgtagtta aacgattgcg
    67321 ttcaaatatt taatccctcc agcactcttt atcataatga taaggaatca ctgattttga
    67381 gaaaagagaa aaagtgataa atgggctggc aataataatt ttcaggagtg attttaattc
    67441 tcatttggca cctgtgagtt cattcacaaa aagccattaa gtttcgagcc gcctcacatt
    67501 tttttatatt tcccgtcaaa cctggcaaga gtggtgcgat tgttgctcta tccccctaaa
    67561 ccaccggatt tctcaacacc ggtcactcaa tgatatctgt ataagctaag gagagggtta
    67621 tgggggatat tatgcgtccc attccgtttg aggaactttt gacgcgcata tttgatgaat
    67681 accaacaaca acgctcaatc tttggtattc ccgagcaaca gttttactca cccgtaaaaa
    67741 gtaaaactgt tagcgtcttc ggtgaaacct gtgccactcc cgtcggccct gccgctggcc
    67801 cgcacacgca actcgcgcaa aatattgtca cttcctggct gactggcgga cgcttcatcg
    67861 aactaaaaac cgtccaaatt cttgaccgtc tggagctgga aaagccctgt atcgatgccg
    67921 aagacgagtg ctttaacacc gaatggtcta ccgaatttac cctgcttaaa gcctgggatg
    67981 aatacctcaa agcctggttt gccctgcacc ttctcgaagc gatgttccag ccttctgatt
    68041 ccggtaaatc gttcatcttt aatatgagcg tcggttacaa cctcgaaggt attaagcaac
    68101 cgccgatgca gcagttcatc gacaatatga tggacgcatc tgaccatccg aaattcgctc
    68161 aataccgcga tgcacttaat aagctactcc aggatgaggc atttttagcc cgccacggat
    68221 tgcaggaaaa acgcgaaagc ttgcaagcct tacccgctcg catccccacc agcatggtac
    68281 aaggtgttac cctctccacc atgcacggct gtcctccgca tgaaatcgaa gccatttgcc
    68341 gctacatgct ggaagaaaaa ggactcaaca cctttgtgaa actcaacccg accttactgg
    68401 ggtacgcgcg tgttcgtgag atcctcgatg tctgcggttt cggttacatc ggcttaaaag
    68461 aagagtcatt tgatcacgac ctcaagctga cgcaagcact ggaaatgctg gaacgcctga
    68521 tggcactggc aaaagaaaaa tcactcggct ttggcgtaaa actgactaac actctcggca
    68581 ccatcaacaa taaaggcgca ctgcccggtg aagagatgta tatgtcaggc cgtgcgctgt
    68641 tcccgctctc catcaacgtt gcagcagttc tctctcgcgc ctttgacggc aaactgccca
    68701 tttcttattc cggtggtgcc agtcagctga ctatccgcga tatttttgat actggtattc
    68761 gccctattac tatggcaacc gacctgctga aacctggcgg ctatctgcgc ttaagtgcct
    68821 gcatgcgcga gctggaaggc tccgacgcct gggagcttaa ccacgttgac gtcgaacgac
    68881 tgaacagact ggcagcagac gcgttaacca tggaatacac ccagaaacac tggaagccag
    68941 aagagcgtat tgaagtggct gaagacctgc cgctgaccga ttgctacgtt gccccctgtg
    69001 ttactgcctg cgctatcaag caagatattc cggaatacat ccgtctgctt ggcgaacacc
    69061 gctatgccga cgcgctggaa ctcatctatc aacgcaacgc cctgcccgcc attaccggtc
    69121 atatttgcga tcaccagtgc caatacaact gtacccgcct ggattacgac agtgcgctga
    69181 atatccgcga actgaaaaaa gtcgccctgg aaaaaggttg ggatgaatat aagcaacgct
    69241 ggcacaaacc agccggttcc ggttcacgcc atccggtagc cgtgattggt gcaggtccgg
    69301 cgggtctggc cgcaggttac ttccttgcca gagcgggcca tccggtcacg ctgtttgaac
    69361 gcgaagccaa tgcgggcggc gtggtgaaaa atatcattcc tcagttccgt attcctgcag
    69421 agttaattca gcacgatatc gattttgttg ccgctcacgg cgtgaaattt gagtacggtt
    69481 gctcacccga tttgaccgtt gaacagttaa aaaatcaggg cttccactat gttctgattg
    69541 ccaccggcac tgataaaaat agcggtgtga aactggcggg cgacaaccaa aatgtctgga
    69601 aatcactccc tttcctgcgt gaatacaaca agggcaccgc gctcaagctg ggcaaacatg
    69661 tggtcgttgt cggggcgggt aacaccgcaa tggactgcgc tcgtgcggcg ttacgcgttc
    69721 caggcgtaga aaaagcaacg gtcgtttacc gtcgttcact gcaagaaatg cccgcatggc
    69781 gcgaagagta tgaagaagcg ttgcacgacg gcgtggagtt ccgttttctg aataatccgg
    69841 aacgtttcga tgctgatggc accttaacct tgcgcgttat gtcgcttggc gaacctgatg
    69901 agaaaggtcg tcgccgtccg gttgaaacca acgaaacagt aacactgcat gtggacagtc
    69961 tgatcaccgc cattggtgaa cagcaggata ctgaagccct gaatgcgatg ggcgtgccgc
    70021 tggacaaaaa cggctggcca gacgtcgacc ataatggcga aacgcgtctg actgacgtct
    70081 ttatgatcgg cgacgtacag cgcggaccat cctccattgt cgctgctgtc ggaaccgcgc
    70141 gtcgggcgac cgataccatc cttagtcggg aaaatatccg ttcccaccag aacgataaat
    70201 actggaacaa cgtaaatccg gcggaaatct atcaacgtaa aggcgatatc tctgtcactc
    70261 tggtgaacag tgacgatcgt gacgcgtttg tcgcacagga agccgcacgc tgccttgaat
    70321 gtaactacgt ttgcagcaag tgtgtggatg tctgcccgaa ccgcgccaac gtatccattg
    70381 cggttcctgg cttccagaac cgtttccaga cgctgcatct cgatgcctac tgcaacgaat
    70441 gcggcaactg cgcccaattc tgcccgtgga acggtaaacc gtacaaagac aaaatcaccg
    70501 tcttcagcct gtcgcaagac tttgataaca gcagtaaccc aggcttcctt gtggaagatt
    70561 gccgggtacg cgtacgtctg aataaccaaa gctgggtgtt aaacatcgac agcgaaggtc
    70621 agttcaacaa cgtaccaccg gagctgaacg atatgtgccg catcattagc catgtccacc
    70681 agcatcatca ttatctgctg ggccgcgtgg aggtgtaatc atgttgattc tgaagaatgt
    70741 caccgcagtg cagttacacc cggcgaaagt gcaggaaggc gttgatatcg ccatcgaaaa
    70801 tgatgtgatt gtcgctatcg gcgatgccct gacgcaacgc taccccgatg ccagctacaa
    70861 agagatgcat ggtcggattg tgatgccggg aattgtctgc tcgcacaacc atttttactc
    70921 ggggctttcc cgcggaatta tggcaaacat cgccccctgc ccggatttca tctcaacgct
    70981 gaaaaatctc tggtggcggc tcgatcgcgc tcttgatgaa gagtcgctct attacagcgg
    71041 actgatttgt tccctggaag cgattaagag cggatgtaca tcggttatcg atcaccatgc
    71101 ctctccggcg tatatcgacg ggtcgctctc cacattgcgc aacgcatttt taaaagttgg
    71161 cctgcgcgcg atgacctgtt ttgaaactac tgaccgtaac aacggcatca aagagttgca
    71221 ggaaggtgta gaagaaaaca tccgcttcac ccgtcagatt gatgaggcga agaaagcagc
    71281 aaccgagccg tatctggtgg aagcacatat cggcgctcac gcgccgttta ccgtgccgga
    71341 tgccggtctg gagatgctgc gtgaagccgt gaaaagcaca ggtcgtggtt tgcatattca
    71401 cgttgcggaa gacctttacg acgtttccta cagtcaccat tggtacggca aagacctgct
    71461 ggcacgactt gcgcaattcg atctcatcga cagcaaaacg ctggtcgctc atgggctgta
    71521 cctgtcgaaa gatgacatcg tcctactcaa tcagcgcgat gcgttcctgg tgcataacgc
    71581 ccgttcaaac atgaacaacc atgtcggcta caaccatcac cttagcgaca tccgcaatct
    71641 ggcgttggga acggacggca ttggttcgga catgtttgaa gagatgaaat ttgccttctt
    71701 taaacatcgc gatgcgggtg gcccgctgtg gcctgacagt tttgccaaag cactggctaa
    71761 cggcaacgaa ctgatgagcc gcaactttgg cgcgaaattt gggcttctgg aagccggtta
    71821 caaagccgat ttaaccattt gcgattacaa ctcgccgacg ccgctgctgg cagacaatat
    71881 cgccgggcat atcgctttcg gtatgggctc aggtagcgtt cacagcgtga tggtcaatgg
    71941 tgtgatggtc tatgaagacc gtcagtttaa cttcgattgc gattccattt atgcgcaagc
    72001 cagaaaagcc gctgccagta tgtggcgtcg gatggatgcg ctggcataaa taacagctcc
    72061 cctcttcttt cagagaagag gggaaattaa ggaaagacga tgattgaaca atttttcaga
    72121 cccgactctg tcgaacaggc gctggaactg aagcgccgct accaggatga agccgtctgg
    72181 ttcgccgggg gcagcaaact caacgctaca ccaacccgta ccgataaaaa gattgccatt
    72241 tccttgcagg atctggagct ggactggatt gactgggata acggtgcact acgaattggc
    72301 gcaatgtctc gcttgcagcc actgcgtgat gcgcgattta ttcctgcagc actgcgggaa
    72361 gctctcggtt ttgtctactc tcgccatgtt cgtaatcagt cgaccattgg tggtgaaatt
    72421 gccgcccggc aagaagagtc agtgctgctt cccgtcctgc tggcactgga tgctgaactg
    72481 gtttttggca acggcgaaac gctgtcaatc gaggactacc tggcctgccc atgcgatcgc
    72541 ctgttaaccg aaattatcat taaagatccg tatcgcacct gtgcgactcg caaaattagc
    72601 cgttctcagg caggtttaac cgtcgtgacg gcagccgttg caataacaga ccacgacggt
    72661 atgcgaattg cgctggatgg cgtcgccagt aaagcactgc gtctgcatga tgttgaaact
    72721 caaaatctgg aaggcaatgc actggaacag gctgtcgcca acgccatttt cccgcaggaa
    72781 gatttgcggg gcagcgtggc ctataaacgc tatatcacgg gagttctggt agccgacctg
    72841 tatgccgact gccaacaggc tggggaggaa gccgtatgat catccacttt actttaaatg
    72901 gcgcgcctca ggagctaacc gttaatccag gcgaaaacgt gcaaaagctg ttgtttaaca
    72961 tgggaatgca ctctgtacgc aacagtgatg atggctttgg gtttgccggt tctgacgcaa
    73021 ttatctttaa cggtaatatc gttaacgcgt ccttgcttat cgccgcacag ttagagaagg
    73081 cagatattcg taccgcagaa tctctgggca aatggaatga gttaagtctg gttcaacagg
    73141 ccatggttga tgttggcgtg gtgcagtctg gttataacga tccagctgcg gctctgatta
    73201 tcaccgatct tctcgatcgc atcgacgcac ctacccgcga agagatcgac gacgcactct
    73261 caggtctgtt tagccgcgat gctggctggc agcaatacta tcaggtcatt gaactggcgg
    73321 ttgcacgtaa aaataatccg caggccacca ttgatatcgc tccgactttc cgtgacgacc
    73381 ttgaagtcat tggcaagcat tatcctaaaa ctgatgccgc gaaaatggtg caggcgaaac
    73441 cctgctatgt tgaagatcgc gtaacggctg acgcctgcgt cattaaaatg ttacgtagcc
    73501 cacacgctca cgcactgatt actcatctgg atgtcagcaa agctgaagcc ttaccgggcg
    73561 tcgttcacgt tattactcac ctgaattgcc cggatattta ctataccccg ggtggtcaga
    73621 gcgcaccgga accgtcaccg cttgaccgcc gaatgttcgg caagaaaatg cgtcacgtcg
    73681 gcgatcgcgt tgctgcggta gtagccgaaa gtgaagacat tgcgctcgaa gcactgaagc
    73741 tcatcgacgt tgaatatgaa gtgcttaagc cggtaatgtc gattgacgag gcaatggcgg
    73801 aagatgcgcc tgtcgtgcac gatgaaccgg tggtgtatgt tgctggtgcg ccagatactc
    73861 tggaagatga taacagccat gcagcccagc gcggcgagca tatgatcatc aacttcccga
    73921 tcggttctcg cccacgcaaa aatatcgccg ccagtattca tggtcatatt ggcgatatgg
    73981 acaaaggctt tgccgatgcc gatgtgatca ttgagcgaac ctataattca acgcaggcac
    74041 agcagtgccc gactgaaaca catatctgct ttacccgtat ggacggcgat cgtctggtga
    74101 tccacgcctc cacccaggta ccatggcact tacgccgcca ggtcgcgcgc ctcgtgggca
    74161 tgaaacagca taaagttcat gtcattaaag agcgagttgg cggcggtttt ggttccaaac
    74221 aggacatcct gctggaagaa gtgtgcgcct gggcaacctg cgtgaccggg cgtccggtac
    74281 ttttccgcta cacccgtgaa gaagagttta ttgctaacac ctctcgtcac gtcgcgaaag
    74341 tcaccgtcaa actgggcgcg aaaaaagatg gtcgcctgac ggcagtgaag atggatttcc
    74401 gcgccaacac gggtccttac ggtaaccact cactcaccgt accgtgtaac ggaccggcgc
    74461 tgtcgctgcc gttatatcca tgcgataacg tcgattttca ggtcaccacc tactacagca
    74521 acatttgccc aaatggtgct tatcagggtt atggcgcacc gaaaggtaac ttcgctatca
    74581 ccatggcatt agcggaactg gctgaacagt tacagatcga ccaactggaa attatcgaac
    74641 gtaaccgggt acacgaaggg caagagctga aaattctcgg tgcaatcggt gaaggtaaag
    74701 cgccgacctc cgttccttcc gccgccagct gcgcactgga agagatcctg cgtcagggtc
    74761 gcgagatgat ccaatggtct tcaccaaaac cgcaaaatgg tgactggcac atcggtcgcg
    74821 gcgtcgccat tatcatgcag aaatcgggta tcccggatat cgatcaggct aactgcatga
    74881 tcaaactgga atcggatggc acctttatcg ttcattccgg tggtgcggat attggtactg
    74941 gtctggatac tgtggtgacc aaactggcag cagaagtgct gcactgccca ccgcaggacg
    75001 tgcatgttat ctctggtgat accgatcatg cactgtttga taaaggcgca tatgcctcgt
    75061 ccggtacttg cttctcgggt aacgctgcgc gtttggcagc ggaaaatctg cgggagaaaa
    75121 tcctgttcca cggcgcgcaa atattgggtg agccagtggc agatgttcaa ctagcaacgc
    75181 cgggcgtcgt tcgcggcaag aaaggcgaag ttagtttcgg agagatagcc cataaaggcg
    75241 aaaccggcac cggctttggt tcactggtgg gaactggcag ttatatcaca cctgatttcg
    75301 ccttcccgta tggcgcaaac ttcgctgaag ttgccgtcaa cacgcgtacg ggtgaaatcc
    75361 gcctggataa attctacgcc ttgctggact gcggtacacc ggtcaatcca gagttagcgt
    75421 tgggacaaat ctacggtgcc accctgcgtg ctatcggcca cagtatgagc gaagagatca
    75481 tttatgacgc cgaaggtcac ccgttaacgc gtgatttacg cagttacggc gcaccgaaaa
    75541 ttggtgacat tccgcgtgat ttccgcgctg tgctggtgcc gagcgacgat aaagtcggcc
    75601 cattcggggc gaaatcgatc tcggaaatcg gtgtaaatgg cgcagctccg gcgattgcta
    75661 ccgcaattca cgatgcctgc ggcatctggt tacgcgaatg gcatttcaca ccggagaaaa
    75721 tactcaccgc gctggaaaaa atataagtaa taaatggccg cttcggcggc ctgtttctct
    75781 gtttgaacga tgactaaata gtgactgcga aaatgagata agccgttctc aaggcgtcct
    75841 gcgccccaaa ttcgtgggaa tttattttac taattcagat gatcaaattt actttaaaag
    75901 gagtgaaggg atgtctgata taaaccatgc aggttctgac cttatatttg aactggagga
    75961 tcgccctccc tttcatcagg ctctcgtagg tgccattacc catctgttgg caattttcgt
    76021 tccgatggta acccccgcgt taatcgtggg tgcggcctta cagctttccg ctgaaacaac
    76081 tgcctatctt gtttctatgg cgatgatcgc ctctggtatt ggtacctggt tacaagtaaa
    76141 ccgctacggc atcgtcggtt ctggtttact ttcaattcag tcagtcaatt tttcatttgt
    76201 tacggtcatg attgcgctgg gcagcagcat gaaaagcgac ggttttcacg aagagttaat
    76261 catgtcgtcg ctcctcggcg tctccttcgt tggcgcattt ctggttgtcg gctcttcttt
    76321 tatcctgccc tatttacgtc gggttattac gcctaccgtc agcggcattg tggtgctgat
    76381 gatcggctta agcctgatta aagtcggcat tattgatttt ggtggaggat ttgcagccaa
    76441 aagcagcggt acgttcggca attacgaaca tctcggcgtt ggtttattgg ttttgattgt
    76501 ggtgatcggc tttaactgct gtcgcagtcc gttgctacgc atgggaggga tcgccattgg
    76561 gctatgtgtc ggctatatcg catcgttatg cctgggcatg gtggatttca gcagtatgcg
    76621 caatttgccg ttaatcacca tcccgcatcc gttcaaatac ggctttagtt ttagcttcca
    76681 tcagttcctg gtggttggca cgatttatct gcttagcgtg ctggaagctg tcggcgatat
    76741 caccgccacg gcaatggttt cccgccgtcc cattcagggg gaagagtatc agtcccgact
    76801 gaaaggcggc gtgctggcag atggtctggt ttctgttatc gcctccgctg tcggttcatt
    76861 accattaacc acgtttgcgc aaaataatgg ggttattcag atgactggcg tcgcttcacg
    76921 ttatgtcggg cgaaccatcg cggtaatgct ggttatcctc ggcttatttc cgatgattgg
    76981 cggcttcttc acgaccattc cctcagcagt tctgggaggc gcaatgacgt tgatgttttc
    77041 catgattgcc atcgcaggga ttcgcatcat catcaccaac ggtttaaagc gccgtgaaac
    77101 gcttattgtt gccacttctt taggtttagg gcttggtatc tcctacgatc ccgaaatttt
    77161 taaaatattg ccagcctcta tttatgtatt agttgaaaac cctatttgtg ctggcgggtt
    77221 aactgcgatt ttattaaata ttatcctccc tggtggctac cgacaggaaa acgttctgcc
    77281 tggtattacc tcagcggaag agatggatta acagtaaagg agtcaatgat gtcaggagaa
    77341 cacacgttaa aagcggtacg aggcagtttt attgatgtca cccgtacggt cgataacccg
    77401 gaagaaattg cctctgcgct gcggtttatt gaggatggtt tattactcat taaacaggga
    77461 aaagtggaat ggtttggcga atgggaagac ggaaagcatc aaattcctga caccattcgc
    77521 gtgcgcgact atcgcggcaa actgatagta ccgggcttta tcgatacaca tatccattat
    77581 ccgcaaagtg aaatggtggg ggcctatggt gaacaattgc tggagtggtt gaataaacac
    77641 accttcccta ctgaacgtcg ttatgaggat ttagagtacg cccgcgagat gtcggcgttc
    77701 ttcatcaagc agcttttacg taacggaacc accacggcgc tggtgtttgg cactgttcat
    77761 ccacaatccg ttgatgcgct gtttgaagcc gccagtcata tcaatatgcg tatgattgcc
    77821 ggtaaagtga tgatggaccg aaacgcaccg gattatctgc tcgacactgc cgaaagcagc
    77881 tatcaccaaa gcaaagaact gattgaacgc tggcacaaaa atggtcgtct gttgtatgcg
    77941 attacgccac gcttcgcccc tacctcatct cctgaacaga tggcgatggc gcaacgcctg
    78001 aaagaagaat atccggatac atgggtacat acccatctct gtgaaaacaa agatgaaatt
    78061 gcctgggtga aatcgcttta tcctgaccat gatggttatc ttgatgttta ccatcagtac
    78121 ggcctgaccg gtaaaaactg cgtctttgct cactgcgtcc atctcgaaga aaaagagtgg
    78181 gatcgtctca gcgaaaccaa atccagcatt gctttctgtc cgacctccaa cctttacctc
    78241 ggcagcggct tattcaactt gaaaaaagca tggcagaaga aagtcaaagt gggcatggga
    78301 acggatatcg gtgccggaac aacttttaac atgctgcaaa cgctgaacga agcctacaag
    78361 gtattgcaat tacaaggcta tcgcctctcg gcatatgaag cgttttacct ggccacgctc
    78421 ggcggagcga aatctctggg ccttgacgat ttgattggca actttttacc tggcaaagag
    78481 gctgatttcg tggtgatgga acccactgcc actccgctac agcagctgcg ctatgacaac
    78541 tctgtttctt tagtcgacaa attgttcgtg atgatgacgt tgggcgatga ccgttcgatc
    78601 taccgcacct acgttgatgg tcgtctggtg tacgaacgca actaataata aaactttaac
    78661 atcctcgtga ggacatcatt atgtctggag acatcctaca aacaccggac gcaccaaagc
    78721 cacagggcgc gctggataat tattttaaaa ttaccgctcg tggcagtacc gttcgtcagg
    78781 aagtactggc tggcttaacg acctttctgg ccatggttta ttccgttatc gtcgttccgg
    78841 gaatgctggg caaagcaggt tttcctcccg cagctgtgtt tgttgccacc tgtctggtcg
    78901 cgggcttcgg ctcgttgctg atggggttat gggccaattt gccaatggcg attggttgcg
    78961 ctatttcctt gacggcgttt accgcattca gtctggtact cgggcaacaa attagcgttc
    79021 ctgtcgcact gggcgcagtc tttctgatgg gcgtcatctt caccgctatt tccgtaaccg
    79081 gtgtgcgtac ctggatctta cgtaatttgc cgatggggat cgctcacggt acaggtatcg
    79141 gtatcggcct gtttctgctg ctgattgctg ctaacggtgt gggaatggtt ataaaaaacc
    79201 cgattgaagg cttgccagtg gcgctcggtg cctttacctc cttcccggtg atgatgagct
    79261 tactggggct ggcggtcatc ttcggtctgg aaaagtgccg cgtacccggc gggatcttgt
    79321 tggtgattat tgcaatttcg atcatcggct taatctttga cccagcggtg aagtaccacg
    79381 gtctggtggc gatgccaagc ctgactggcg aagatggtaa gtctctgatt ttcagcctcg
    79441 atattatggg cgcactccag ccaactgtac ttccgagtgt actggcattg gtgatgaccg
    79501 cagtgttcga cgccactggc accatccgtg ccgtcgccgg tcaggcgaat ttgttggata
    79561 aagacaacca gatcatcaac ggcggcaaag ccctgaccag tgactcagta agttcaatat
    79621 tctccggcct ggtgggcgca gcgcccgcgg cggtttatat cgaatcagcg gcaggaaccg
    79681 ccgccggggg gaaaaccggt ttaaccgcaa ccgtggttgg tgtgttgttc ctgatgattc
    79741 tgtttttatc accgttatcg tttctgatcc ccggttatgc cacagctccc gcactgatgt
    79801 acgtgggttt gctgatgtta agcaacgtct cgaagctgga tttcaacgat tttattgacg
    79861 caatggctgg cctggtgtgt gccgtgttca tcgttctgac ttgtaatatc gttaccggta
    79921 ttatgctggg ctttgtaaca ctggtggtgg gtcgcgtctt tgcgcgcgaa tggcaaaagc
    79981 tgaatattgg tacggtgatc attactgccg cactggtcgc gttttacgcg ggtggttggg
    80041 caatctaata gattctccgc gcctttcagc gcggagattt ctttcacaga ggattctcac
    80101 tgctggcaac aatacgctgc tggcggactc gcctgagttc tctttcagtc agcaactgca
    80161 gcgcctgtgt cgggcaagat tcaacgcagg ctggcccctc ttcccgctgt tcacagagat
    80221 cgcatttcac gatttgttgc cgggtatccc ccggcaatga ctgaatggtg atcattccaa
    80281 acgggcacgc actgacgcaa ctctgacagc caatacaacg ggcagaattt gcctgcacca
    80341 cctgctcgcc catcgtcagc gcccccacgg gacaagcgcc aacacaaggg gcgttttcac
    80401 actgatggca catcaccggc gcactgatgc tatccagccg ttgtaccttc agccggggta
    80461 aaaagatatc ggcattcaac tcctgttctg aagggtgagc gaccacacag gccacttcac
    80521 aagtacggca gccaatacag tcagccggat taacgataat taacgatttc atcacgatgc
    80581 cttcgtatca aacagagtta acatatcgcg cgccgcctgc cttcctgcgg ccattgcagt
    80641 gacaaccaga tctgcgccat gaactgcatc accaccagca aagacttttt tcagatgcgt
    80701 ctgggtgggt aaatacccga cgtcgccggt ttgaatcagg ccccatttat cgagtttaat
    80761 tccgctgccc tgcaaccacg gcatggtatg tgcctggaaa ccaaaggcca taatgagaac
    80821 atcggcgggc aattcaaact ctgaacccgc aaccggacga ggacgacggc ggccatccgg
    80881 ccccggctca cccatagcgg tacgaatcag gcccaccgcc gttaagcgtc catcttcatc
    80941 acaagcgata tattgcggct gaacattgaa ctgaaactca acaccttcct cgcgggcatt
    81001 gaccacctct ttgcgcgaac ccggcatact gacttcatca cgacgatacg cacaggtcac
    81061 gctggcagca ttaaggcgga tggaagtccg caaacaatcc attgtcgtat cgccaccgcc
    81121 caataccaca actcgcttac cttccacatc cgtcagcgga tactctgcag actccggcaa
    81181 tcccatgagc tggcgggtat gggcggtcag gaacggtaac gcctgaatga caccaggcgc
    81241 atcttcatgc ggcagatctg ctcgcatcat cccgtaagtc cccacgccga ggaaaacagc
    81301 atcatattcc gccgttaatt cgttgaaaga gatatcgcgg ccaatttcac agttgagatg
    81361 gaaatcgatt cccattgcgg tgaatatctc tcgccgctgg cttaataccg ttttatcgag
    81421 tttgaaagga ggaatgccaa aagtcagcat accgccaatt tctggatggc gatcaaagac
    81481 atcaacctga actcccgcgc gcgccagaat atcagcacac cctaatcctg caggtccagc
    81541 gccaatcacc gccacttttt cgctacgggg aacaactttg ctgacatcgg gacgccagcc
    81601 catcgccagc gcagtatcgg tgatgtagcg ttccagatta ccgatagaga ctgcgccaga
    81661 gtgatctttc aaagtacatg caccttcaca aagacggtcc tgtggacata ccctgccgca
    81721 gatttcgggt aaggaactgg tctggtggca aagttctgcc gcttcaataa tctttccttc
    81781 ctgtaccaga cggatgtaat ccggaatagc gttatgcagc ggacaatgcc agttgcagtt
    81841 agctttttcg gcacaataaa cacagcggtc actctcataa gtcgcttgtt gtggatccag
    81901 cccgcaatag atttcgccaa agtgggtttt ccgttcactc gctgaaattt tatctgcgcc
    81961 tttacgcgag ttaacgggga gcaacgctgc actgcgagat ggctgagcgt ctgatgacgc
    82021 ttttcctgct gccgttttgc gctggcgggc cacctttatc tgctgcaacc ctttatcgtc
    82081 catcagccgt aacgcctgtg ttgggcagac gtcaatacag gcttgcgtgc cggaactgcg
    82141 ctggttacaa aggtcgcatt tctgtgcaat cgtatcgacc atctcaacga cgccaaaggg
    82201 gcaagcgatt gcgcatcttt tacaaccaat acatttttgc tcgtccagtt gtacgctatc
    82261 ggactggaaa gtcagagcat taaccggaca agccgtaacg caaggggcat tgttgcagtg
    82321 atggcaggcc accggattcg cagcctggcc tttccctaca acgtggatac gcggtcgaaa
    82381 gtcactgtga ctcagcggcc agttttcttg attatgtgcc accgcacagg caatttcaca
    82441 agcatggcag cctatacatt ccgcagcttc agcagcgata aacttattca tttgcatccc
    82501 tttcatttaa tgagttatgt cttctcaaat ttcgcgatgc aataaacggg catatattag
    82561 gtagcatgac cgttttaatt ataattttgc aactgagttc aaattattgc ccctcaatct
    82621 atgccgcttt cattatttca acattgccga tcaaaagaat gctatccaga taaaaacgat
    82681 taaatgcgag agtgcgacat gccagaatga ttaatgaaat atcaatatga gaaaattaca
    82741 gataattcca ttgtcaggtt ctcttctcat tttcgtggtt taaccacgat tatgtgattg
    82801 cctccgcaat tcctgtctct aactcccctt cctcgcaaaa actggcactc cacgagcatg
    82861 tgtttagaca gtttcatgaa cataaacggt tgctttttac tctggcgggc gaaaggagaa
    82921 acactgatga gcgccataga ttcccaactt ccctcatctt ctgggcaaga ccgcccaact
    82981 gatgaggttg accgcatatt atcaccagga aagctgatca tactcggtct gcaacacgtc
    83041 cttgtcatgt acgcaggtgc agtcgctgtt cctcttatga ttggtgaccg actcggccta
    83101 tcaaaagaag ctattgcgat gctcattagc tcggatctct tttgctgcgg gatcgtcaca
    83161 ttattgcaat gtatcggtat cggccgcttt atggggatcc gcctgccggt gattatgtcg
    83221 gtgaccttcg ccgctgtaac accaatgata gccattggta tgaacccgga tatcggcctg
    83281 ctggggatat tcggtgccac tatcgccgcg ggttttatca ccacattatt agcgccactt
    83341 atcggtcgct tgatgccttt attcccgcca ctggttaccg gtgtggtgat tacttctatc
    83401 gggcttagca tcattcaggt gggtattgac tgggccgccg gaggtaaagg gaatccgcaa
    83461 tatggtaatc ccgtttattt aggtatctcc tttgccgtct taatttttat cttgctcatt
    83521 actcgctatg cgaaaggatt tatgtccaac gtcgccgtat tactggggat tgtatttggc
    83581 tttttacttt cgtggatgat gaatgaagtc aatttatccg ggctacatga tgcttcatgg
    83641 tttgcgattg tcacgccgat gtcatttggt atgccgattt tcgatcccgt ttccattttg
    83701 accatgaccg cagtactcat catcgtattt attgagtcaa tggggatgtt cctggcactg
    83761 ggtgaaatag tcggtcgcaa actctcttcc caggacatta ttcgtgggtt acgcgtagat
    83821 ggggtcggga caatgattgg aggcacgttt aacagcttcc cacatacgtc attttcgcag
    83881 aacgtcgggc tggtcagcgt gacgcgcgtc cacagccgct gggtgtgtat ttcttcggga
    83941 attatattaa tcctgtttgg catggtgccc aaaatggcgg tgctggtcgc ctccattccg
    84001 caatttgtgc tgggcggcgc ggggctggtg atgttcggca tggtactggc gacagggatt
    84061 cgaattctgt cgcgctgtaa ctacaccact aaccgttaca acctctatat tgtggcgatc
    84121 agtctcggtg ttggcatgac gccaacgctc tctcacgatt tcttttctaa gttaccggcc
    84181 gtactgcaac cgttgctgca tagcggcatt atgctcgcaa cccttagcgc cgttgtgctg
    84241 aacgtcttct ttaatggcta ccagcatcat gctgacctgg tgaaggaatc cgtctctgat
    84301 aaagatttaa aagtcaggac agtacgtatg tggcttctga tgcgcaagct gaagaaaaat
    84361 gagcatggag aataatatga atcttttaat gcgcgctata ttcagtctgc tgttgctttt
    84421 tactctctct attcctgtca tttctgattg tgttgcaatg gccattgaaa gtcgcttcaa
    84481 atatatgatg ctgctttttt aaatggtttt tacctgtcga catccgctca aaacgggcgg
    84541 ttgtcgataa acgctcactt ggttaatcat ttcactcttc tattatctat aatgatgagt
    84601 gatcagaatt acatgtgaga aattatgcaa acggaacacg tcattttatt gaatgcacag
    84661 ggagttccca cgggtacgct ggaaaagtat gccgcacaca cggcagacac cctcttacat
    84721 ctcgcgtttt ccagttggct gtttaatgcc aaagggcaat tattagttac ccgccgcgcc
    84781 cttagcaaaa aagcatggcc tggcgtgtgg actaactcgg tttgtgggca cccacaactg
    84841 ggagaaagca acgaagaggc ggtgatccgc cgttgccgtt atgagcttgg cgtagaaatt
    84901 acgcctcctg aatctatcta tcctgacttt cgctaccgcg ccaccgatcc gaatggcatt
    84961 gtggaaaatg aagtgtgtcc ggtatttgcc gcacgcacga ccagtgcgtt acagatcaac
    85021 gatgatgaag tgatggatta tcaatggtgt gatttagcag cggttttacg cggtattgat
    85081 gctacgccgt gggcgttcag tccgtggatg gtgatgcagg cgacaaatcg cgaagccaga
    85141 aaacgattat ctgcatttac ccaacttaaa taaaaaaccc cgacggttgc cggggttgtg
    85201 agcataacgt aatgcttatt ttaccggacg catcgccggg aacagaataa cgtcgcggat
    85261 ggtatggctg ttggtgaaca gcatcaccat acggtcgata ccaattccca gaccggctgt
    85321 cggcggtaag ccatgttcca gtgcggtgac ataatcttcg tcgtagaaca tcgcttcgtc
    85381 gtcacctgca tctttcgcgg caacctgatc caggaagcgc tgcgcctgat cttccgcgtc
    85441 attcagttcg ctaaagccgt taccgatttc acgcccacca atgaagaact caaagcggtc
    85501 tgtgatttcc gggttaacgt cgttacgacg cgccagagga gaaacttctg ccggatattc
    85561 agtaatgaag gtcggctgga tcagatgagc ttctgccact tcttcgaaga tctcggtaac
    85621 gatacggccc agaccccagc tcttttcaac gtggatgccg atagattcag caatcgcttt
    85681 cgcagagtcg aagttgtcca gatccgccat gtcggtttcc gggcgatatt tcttgatcgc
    85741 ttcacgcatg gtcagttttt cgaacggttt accgaagtcc agcgttacgt cgccgtaggt
    85801 cacttccgtc ttaccgagaa tatcctgtgc cagagtacgg aacagcgatt cggtcagctc
    85861 gatcagatct ttgtaatctg cgtaagccat atagagttcc atcatggtga actctgggtt
    85921 atgacgtacg gaaatacctt cgttacggaa gttacggttg atttcgaata cacgctcgaa
    85981 gccaccgacc accagacgct tgaggtacag ttccggcgcg atacgcaggt acatgtcgag
    86041 atccagcgcg ttatggtgag tgataaacgg acgcgcagcg gcaccgccag ggatcacctg
    86101 catcatcggc gtttcaactt ccataaagcc gcggttcacc atgaactggc gaataccaga
    86161 gaggatctgc gagcgcactt taaaggtgtt gcgggattca tcgttagaga tgagatccaa
    86221 ataacgctga cgatagcgcg cttcctgatc ctgcaagccg tggaatttat ccggcagcgg
    86281 acgcagtgct ttggtcagca gacgcagctc ggtacagtgg atagacagtt cgccggtttt
    86341 ggttttgaac agtttacctt tcgcgccgag gatatcgccg aggtcccatt ttttgaactg
    86401 ctcgttgtaa acgccttccg gcagatcgtc acgggcaacg tacaactgaa tgcgaccgcc
    86461 aacgtcctgc agggtaacga aagacgcttt acccataata cgacgggtca tcatgcggcc
    86521 agcaacggcg acttcgatgt tcagcgcttc cagttcttcg ttctctttac cgtcgaattc
    86581 tgcgtgcaat tggtcagagg tatgatcgcg acggaaatcg ttcgggaagg caatcccctg
    86641 ctcacgcagg ttcgccagct tctcacgacg cgttttcagt tcattgttaa gatcgactac
    86701 cgcgtcagcg ccctgtgcgt gttgttcaga catgttggtt cctcataacc ctgctttcaa
    86761 acttgcttcg ataaattgat ccaggctgcc gtccagcacg gcctgcgtgt tgcgagtttc
    86821 taccccggta cgcagatctt taatgcggga gtcatcaagg acataagaac gaatctggct
    86881 gccccagccg atgtcggatt tgttatcttc catcgcctgt ttctcggcat ttttcttctg
    86941 catctccagt tcataaagct tcgctttcat ctgcttcatg gcctggtctt tgttcttgtg
    87001 ctgggaacgg tcgttctggc attgggtcac gatcccggtt gggatgtgag taatacgcac
    87061 cgcagattcg gtacggttaa cgtgctgacc gcccgcgccg gatgcgcgat aaacgtcgat
    87121 gcgcagatcc gctggattga tttcgatatc gatatcatca tcaacttccg ggtaaacaaa
    87181 cgcggagctg aacgacgtgt ggcgacgacc gccggagtca aacgggctct tacgcaccag
    87241 gcggtgaacg ccggtttctg tacgcagcca gccataagcg taatcgccgg agattttgat
    87301 cgtcacggat ttaatacccg ccacttcacc ttccgactct tcgatgattt cagttttgaa
    87361 accacgcgat tcagcccagc gcagatacat acgctcaagc atgctcgccc agtcctgtgc
    87421 ttccgtaccg ccagaccccg cctgaatatc gaggtagcag tcggcgctgt catattcgcc
    87481 agagaacata cggcggaact caagctgcgc cagtttttct tccagggcgt cgagttcagc
    87541 aacggcttcg ttaaaggttt cttcgtcgtc agcttctaca gccagttcca gcagaccaga
    87601 aacatcttcc agcccctgtt tcatttggtc gagggtgtcg acaacggctt cgagggagga
    87661 acgctcttta cccagcgcct gtgcgcgttc gggttcgttc cagacatccg gctgttccag
    87721 ctcggcgttt acttcttcca gacgctcttt cttggcgtcg tagtcaaaga taccccctaa
    87781 gaacgtcgga gcgttccgtg aggtcctgaa tgcgattatt taccggatta atttcaaaca
    87841 tggtctgatt tcttttattg agctagtcaa aatgcggtga taagagcggg attgtaccca
    87901 atccacgctc ttttttatag agaagatgac gctaaattgg ccagatattg tcgatgataa
    87961 tttgcaggct gcggttgccg cgaaactcgt tgatatcgag cttgtaagcc agttgcactt
    88021 cgcgcacgcc gttatccggc cagagggcgg tatcgacatt aaaagcaatc ccgtccagca
    88081 gtggaccgcc gccgaccggt tcgaccatga ctttcaaatg acgttcgccc accagccgct
    88141 gttgcagcag acggaaatga ccatcaaaca gcggctccgg gaacatctgc ccccacgggc
    88201 cagcatcgcg caacagctgc gccacttcca tggtcatttc ggccggactt aacggaccgt
    88261 ccgacaccac ttcgccttgc aatagcgaag ggtccagcca ctcagtaacc agttcgccaa
    88321 accgttgttg aaagagttcg aatttctcct cttccagcga caaacccgcc gccatcgcat
    88381 gaccgccaaa cttgagcatc atgccggggt aaagcgtgtc tagccgctcc agcgcatcac
    88441 gcatatgcag cccctgaatg gagcgaccgg aacctttcag cgtaccatca ccagctggcg
    88501 caaaggcgat aaccggacga tgaaaacgct ctttgatgcg cgaagccaga ataccgacaa
    88561 cgccctgatg ccattcgggg tgatacattg ccagcccgcc gggtagcgtg tcgcggctgc
    88621 gctccagttt ctcgcacaag gtcagggctt caacttgcat tccctgttcg atctcttttc
    88681 gcgtctggtt tagcgcatcg agttcatttg ccagcacgcg cgcttcgccg atgttgtcgc
    88741 acagcaacag cgccacgcca acggacatat cgtccagtcg cccggcagca ttgagacgtg
    88801 gccccagcgc aaaacctaaa tcgctggcgg cgagtttttg tggatcgcga ttggccactt
    88861 ccagcaacgc tttaatcccc ggacggcact ttccggcacg gatgcgactc atcccctgcc
    88921 aggtcagaat gcgattatta gcgtccagcg gcacgacgtc cgccactgtc cccaacgcta
    88981 ccagatccag cagttctgcc agattaggaa ttgcgatgcc gcgctcatca aaccagccct
    89041 gatcgcgcaa aaaggtgcgc agcgccagca tcagataaaa cgccacgcca acgcccgcca
    89101 gtgatttcga cgggaaatta cagtcgcgca agttagggtt aatgatcgct tccgctgcgg
    89161 gtaatgtgtc gcctggcaaa tggtgatcgg taacaataac cggaatgccc aacgaacgag
    89221 cgtgttcaac ccccgcatgg gaggaaatac cgttatccac cgtgacaatt aactgcgcgc
    89281 cacgggcatg agcctgatcg actacttccg ggcttaagcc gtaaccgtct tcgaaacggt
    89341 ttggaaccag gtagtcgata ttgctgcaac caagcgagcg catcgccagc acgcttagag
    89401 ccgtgctggt ggcaccgtcg gcgtcgaaat caccgaccac aataatccgc gttccttcgc
    89461 gaaaagcgtt gtaaaggatc tcaacggcct tttcgacgcc gctcagttgc tgccagggca
    89521 gcatgccttt aacactgcgt tccagttcct gcgcgctacg cacaccccgg ctggcatata
    89581 aacggcgcag caagggaggc aattcagcgg gcaagtcggc cgtttcatcg acttcacggc
    89641 gacgaagttg tatctgttgt ttcacgcgaa ttatttaccg ctggtcattt tttggtgttc
    89701 gtcgaggaat tctttcatgt ctttcggcgg ctggtaaccc ggaacaagtg tgccattgct
    89761 cagcacaact gccggagtac cgctaacgcc aagctggacg ccaagtgcgt aatggtcggc
    89821 aatatctacg tcgcagctgg ctggtgcgac gcttttacct gccatcacat catcaaacgc
    89881 tttgttttta tctttcgcac accagatagc tttcatttct ttctctgcat cgctgtccag
    89941 cccctggcgc gggaaagcaa gataacgcac ggtgatcccc agcgcgttat agtctgccat
    90001 ttgctcatgc agtttgtggc agtaaccaca ggtaatatca gtaaacacgg tgatgacgtg
    90061 tttttcctgc ggcgctttat aaacgatcat ctctttttca agcgcattca actgctttaa
    90121 cagcatctta ttggtgacat tgaccggagc cgtgccacta acgtcataca ttggcccctg
    90181 aatgatatgt ttaccatcat cggtgatgta caacacaccg ctgttagtca gaactgtctt
    90241 catgccagct acgggcgcgg gctgaatatc gctgcttttg atgcccattt tggctaacgt
    90301 ttgttgaatt gccgcgtcat cagcctgaac aaagcctgaa aacgctgcca acaaggtaaa
    90361 taacataaaa cctttcttca taaattttcc tgttcttttc agacatcacg cccgcgggtg
    90421 atgctgttga tgaagttgtc gcagacgctc ggtagcgaca tgcgtataaa tttgcgtggt
    90481 ggagagatcg ctgtggccca gtagcatctg caccacgcgt aaatccgcac catgatttaa
    90541 taagtgagtg gcaaaagcgt gacgcaacac atgcggtgac agcttttcgc tgtcgatacc
    90601 cgccagcacg gcataatgtt taatgcggtg ccagaaggtc tgtcgcgtca tctgctgcgc
    90661 acgctggctg ggaaacaaca cgtcaattga cacaccattc aacagccacg gacgcccatg
    90721 ttccagatag gtttccagcc agtaaaccgc ctcttcacct aacggcacca ggcgctcttt
    90781 gttgccttta ccaatgaccc gcaccacgcc ctgacgcagg ctgatatcac tcattgtcag
    90841 cccgaccagt tcagagacac gcagtccggt agcatacaac acttcaagca tggctttatc
    90901 gcgtagctcc agtggctgat caattaatgg tgcctgtaat aaacgttcga cctgcgcttc
    90961 gcttaaatct tttggcaaac gctggggcaa tttcggtgaa gcgagatgcg cactgggatc
    91021 atcttcacga aacttttcgc gataaagata ctggaacaat cggcgcactg cactcagcaa
    91081 acgcgctgag ctggtggctt tatacccgcc ctccagccgt tctgccagta atgcctgcaa
    91141 atcgtcactt tgcgccgtcg ccagcgtcaa cccgcggtga tgcaaccact ccaccatcat
    91201 tgacagatcg cgacggtaag cgttcaacgt attttcagcc agattttttt ccagccacag
    91261 agcatcaaga aactgctcga tgcgtgccag atcctgtttc acttgcgccc cttatggtca
    91321 ctcatttgat ccattatgcc ttattgtgcc gtgactaaag cgattctgat acactagccg
    91381 caaaagccac agcagaatcg agaagcttac gttatgaata tgggtctttt ttacggttcc
    91441 agcacctgtt acaccgaaat ggcggcagaa aaaatccgcg atattatcgg cccagaactg
    91501 gtgaccttac ataacctcaa ggacgactcc ccgaaattaa tggagcagta cgatgtgctc
    91561 attctgggta tcccgacctg ggattttggc gaaatccagg aagactggga agccgtctgg
    91621 gatcagctcg acgacctgaa cctcgaaggt aaaattgttg cgctgtatgg gcttggcgat
    91681 caactgggat acggcgagtg gttcctcgat gcgctcggta tgctgcatga caaactctcg
    91741 accaaaggcg tgaagttcgt cggctactgg ccaacggaag gatatgaatt taccagtccg
    91801 aaaccggtga ttgctgacgg gcaactgttc gtgggtctgg cgctggatga aactaaccag
    91861 tatgacctta gcgacgagcg tattcaaagc tggtgcgagc aaatcctcaa cgaaatggca
    91921 gagcattacg cctgatgtca ctgacggctt agcacatatg ctttgccgtc atctttatct
    91981 ttgcgtctct tgttgcaaca atatccgccg taaatcccgc cattcggctt cgtccatgct
    92041 gtcagctgcc agccataaat gttgccgttt tccgctgtca gaacgtaaac gcagcatcat
    92101 gccgctctta atcatccacg gcgctttgac gatgctccac tcctgccctt gccaacgcaa
    92161 acgcccgtcc atcaacaagc gaatttcccc ctggcgagca ttaatgcgcc gctggctgcg
    92221 aacgcaatca aacaccacca gcgaaagtaa caccatccat aacggggtgt aactgagcgg
    92281 ccagggaatg agtaaaataa cagcggcaac cagcccatga atcagcaagg aaagccactg
    92341 tgcgcgccag gagacgcgca aatcagattg ccacaggacc acgttcccgg ttccgtgtct
    92401 ggatgagtcg gaccatcatt tccagttctg catcggctgg tttaccgtga ttcatcagcc
    92461 agttaaacag gtccggatcg tcacattcca gcagacgaat aaaggtgcgt ttttcgtcat
    92521 cgcttaagct gtcgtactca tgttcgaaaa acggcatgat tgaaatatcg agttcgcgca
    92581 taccacggcg gcatgcccaa tgaatgcggg ctttgttgtt aatgtccatc ttcttcctgt
    92641 ctcacgaaaa tccagtaccc ggctattgta acgtgttttt cgacttcttt tacgggaata
    92701 tcagtaaaca caatcgcgat cgcgaaatta attcacaaca attcaagggc ttcatttttt
    92761 tggaagtcgc ctcgcagaag gcacagatcg cgcagtgaaa gcacttgcat tgcctcatag
    92821 ctcttttacc attagtgatt aatacgccgt taagcaactc aggactctat tatggctttt
    92881 acaccttttc ctccccgtca gcctacggct tctgcccgtt tgccactgac gctgatgacg
    92941 cttgatgact gggcgcttgc cactattact ggcgcggaca gcgaaaaata tatgcaaggc
    93001 caggtgacag cagatgtcag ccagatgact gaagatcagc acctgctcgc cgcccattgc
    93061 gacgccaaag gtaaaatgtg gagcaattta cgtctgttcc gcgacggcga tggctttgca
    93121 tggattgaac ggcgcagcgt gcgtgaaccg cagctgactg aactgaaaaa atatgcggtg
    93181 ttctctaaag tgaccatcgc gccagacgac gagcgtgtgc tgcttggtgt tgccggtttt
    93241 caggcgcgca ccgcgttggc aaatctcttt agtgaactac cttcgagaga aaaacaggta
    93301 gtcaaagaag gcgcgaccac gttgctatgg tttgaacacc cggcagaacg tttcctgatc
    93361 gtaaccgatg aagctactgc caatatgctg accgataaac tgcgcggtga agcggaactg
    93421 aacaatagcc aacagtggct ggcattaaac attgaagcgg gttttccggt gattgatgcc
    93481 gccaacagcg ggcagtttat cccccaggcg accaacctcc aggcgctggg cggcatcagc
    93541 tttaagaaag gctgctatac cggacaagag atggtggcgc gagcaaaatt ccgtggtgcc
    93601 aacaaacgcg cgctctggtt gctgacgggt agcgccagcc gactgccgga agctggtgaa
    93661 gacttagagc tgaaaatggg cgagaactgg cgtcgtaccg gtacggtgct ggctgcggtc
    93721 aaactggaag atggtcaggt tgtggtgcag gttgtcatga ataacgatat ggaaccggac
    93781 agcatcttcc gcgtgcgtga cgatgcgaat acattgcgta ttgagccact gccatattcg
    93841 ctggaagagt aaatctctgt atcgcatcag gcatttatcg cctgatgcga cactggtgtg
    93901 tcttttcagg cctacaaagg cacgccaatt acacctgccc aatatacaaa tagatcgcca
    93961 gaaagtggca cacactaccg ccgagcacaa agccgtgcca gatggcatga ttgtatggaa
    94021 tgcgcttgca gacgtagaaa atcaccccga gcgaataaac cacaccgcct accgccagta
    94081 aggtaacgct gcccgccgcg agcttaactg ccatttcata aattaccacc agcgacagcc
    94141 agcccatcgc cagataggtc accagagata aaattttgaa tcggtgcgcg atggtcagtt
    94201 taaacagaat acccagcaat gccaggctcc agataacaat catcaacccg cgcgctaacg
    94261 gagaatccag ccccaccagc aaaaacggcg tgtaggttcc ggcaatcaac agataaatag
    94321 cgcagtggtc aaatttcttc agccacattt ttgcccgttg atgaggaatg gcgtgataga
    94381 gcgtcgaagc gaggaacagc aggatcatac tgccgccata gaggctgtaa ctggttatcg
    94441 ccgtggcgct ggcattgaga tccaccgcct gaaccagtag caacaccagc ccaacgatac
    94501 caaacaccag cccaatgccg tgactgacgc tgttggcaat ttcctctgcc agcgaatatc
    94561 cctgcttaat gaggggcttc tgaaccataa cttactccgg aaaaacgtac acgcacatgt
    94621 atacctctcc agcgtaactg agaatagttc cagtgaacac ctgttagcta aaataaattc
    94681 tgatttgaga ttaatctccg aaaaatcatg aaattaaatg cgaaatttca actaacaggc
    94741 gtgagttcaa tttaaagaca tttaaattca atcacataaa actgtgtctg gtcgggatag
    94801 atgtcggcaa tgaccttttt cagttcagtc agggtcatat tttcctgctc tgcatgtttt
    94861 tccgtcagcg tatccagcgt tacggttgag gttgcggtga cttcaatcgt gcaaaaataa
    94921 ccgtcatctt caaaacgtcc gacacgaagc acatcacccg ttttgaagtg cgattcagac
    94981 tcgtcgcgga tggtgatggt tttacgccca gccagaatgt catcctggaa acgttgaaaa
    95041 aaagtgatgt cgtttggctg catggtaata tttcctgtaa gaattgactc atctggagcc
    95101 tatgatagtg aaaaaactca ccttaccgaa agatttctta tggggcggcg cagttgccgc
    95161 tcatcaggtc gaaggcggct ggaacaaagg cggcaaaggg ccgagcattt gtgacgttct
    95221 gaccggtggc gcacacggcg tgccgcgcga aatcaccaaa gaagttgtgc ctggcaaata
    95281 ctatccaaac catgaagccg ttgattttta tggtcactac aaggaggaca tcaagctatt
    95341 tgccgaaatg ggcttcaaat gttttcgtac ttccatcgcc tggacgcgca tttttccaaa
    95401 aggcgatgaa gctcagccaa acgaagaagg gctgaagttc tacgatgata tgatcgatga
    95461 actgctgaaa tacaacatcg aaccggtgat caccctctcc cactttgaaa tgccgctgca
    95521 tctggtgcag caatatggta gctggaccaa ccgtaaagtg gttgatttct ttgtccgttt
    95581 cgcggaagtg gtattcgaac gctataagca caaagtcaaa tactggatga ccttcaacga
    95641 aattaacaac cagcgtaact ggcgtgcacc gctgttcggt tactgctgct ccggcgtggt
    95701 gtataccgaa catgaaaacc cggaagagac catgtatcag gtgctgcatc accagtttgt
    95761 cgccagcgcc ctggcggtga aagccgcgca tcgcatcaac ccggagatga aagtcggttg
    95821 tatgctggcg atggtgccgc tctatcccta ctcctgtaac ccggacgatg tgatgtttgc
    95881 ccagaagtcg atgcgcgaac gttacgtctt taccgatgtg cagttgcgtg gctattaccc
    95941 gtcctatgtg ttgaacgagt gggaacgccg cggatttaac atcaaaatgg aagacggcga
    96001 tctggatgta ctgcgcgaag gcacctgcga ttatctcggc ttcagctatt acatgaccaa
    96061 cgcggtgaag gccgaaggcg gcaccggcga tgcgatctct ggttttgaag gcagcgtacc
    96121 gaacccgtat gttaaagcgt ctgactgggg ctggcagatt gatccggttg gtctgcgtta
    96181 cgcgctttgc gagctgtatg agcgttacca gaagccgctg tttattgtcg aaaacggttt
    96241 tggcgcttac gacaaagtgg aagatgatgg cagcatcaat gacgattacc gcattgacta
    96301 cctgcgcgcc catattgaag agatgaaaaa agcggtgact tacgatggcg tggatctgat
    96361 gggctacaca ccgtggggct gcatcgactg cgtgtcgttc actaccgggc agtacagcaa
    96421 acgctacggc tttatctatg tgaataaaca tgacgacggt actggcgata tgtcgcgttc
    96481 acgtaagaag agctttaact ggtacaaaga ggtgattgcc agcaacggcg agaatttgta
    96541 attagccgat gtgcctgatg tgctccgctc atcaggcctg gcactctttt aatatattga
    96601 gctcgcaata ttttatatta cgcctcaacc gaaacacaca aagcgcactt tattaacaag
    96661 cgaaaaaggc gccgaagcgc ctttagaaga tagtcgaatc agtaaattac tggtattcgc
    96721 taatcggtac gcaggagcag aacaggttac ggtcgccgta aacatcatcc agacgtttca
    96781 cggtcggcca gtatttgtct gccacacctg ccgggaatac tgcaacttca cgactgtacg
    96841 gatgcgccca ctcggcgacc agttcgctct gaatgtgcgg cgcgttcacc agcgggttat
    96901 cttccagcgg ccagacaccg gctttcacct ggtcaatttc tgcgcggata gccagcatcg
    96961 catcgataaa gcgatccagt tccactttgc tttcagattc agtcggttca accatcagcg
    97021 tacccgccac cgggaacgac atggtcggcg cgtggaaacc gtagtcgatc aggcgcttgg
    97081 caatatccag ctcgctgatg ccggtttctt ctttcagcgg gcgaatatcg agaatacatt
    97141 cgtgcgccac gcgaccgtcg cgaccggtat acagcaccgg gaaggcatcc tgcagacggc
    97201 tggcaatata gttggcgtta agaattgcca cctggcttgc ttttttcagc ccttctgcgc
    97261 ccatcatgcg gatgtacatc cagctgattg gcaggataga ggcactaccg aacggtgccg
    97321 cagaaaccgc gccctgacgg attaacatgc cttcgatttg caccacgcta tgacccggta
    97381 caaacggagc cagatgcgct ttcacaccga tcggtcccat acccggacca ccaccgccat
    97441 gcggaatgca gaaagtttta tgcaggttaa ggtgggaaac gtccgcacca ataaagcccg
    97501 gcgaggtgat gccaacctga gcgttcatgt tcgcgccatc aaggtaaacc tgaccgccga
    97561 actgatgcac gacttcacac acttcacgga tcgtttcttc atacacgccg tgggtggaag
    97621 gataggtcac catgatacag gagaggttat cgcccgcctg ttcggctttc gcgcgcagat
    97681 cagtcagatc gatgttgccg tttttatcac acgccacaac caccacctgc attcctgcca
    97741 tatgcgcgga agccgggtta gtgccgtgcg cagaagccgg gatcaggcag atatcgcgat
    97801 gcccttcgtt gcggctttca tgataatgac gaatcgccag caggcccgcg tattcgccct
    97861 gtgcgccaga gttcggctgc atacaaacgg cgtcgtaacc ggtcagtttc accagccact
    97921 cagccagctg cgcgatcatc tgctgataac cttcagcctg ttccggcggg cagaacgggt
    97981 gcagttcggc aaattccggc caggtgatcg ggatcatctc ggcggcggcg ttcagtttca
    98041 tggtgcagga acccagcggg atcatcgcct gattcagcgc cagatcttta cgctccagcg
    98101 agtgcatata gcgcatcatt tcggtttcgc tgtggtagcg attaaacacc ggatgggtga
    98161 ggatttcgtc gtcgcgcagc atcgcagcct gaatagagcg actgtcgtga gccacgtctt
    98221 tgtccagtgt gtcgatgtcc agcccgtggt tatcgcccaa cagcacgctg aaaagctgca
    98281 tcacgttttc gcgcgtagtg gtttcatcaa gggtgatccc aaccgcgttc agaatatcgc
    98341 tacgcaggtt gatttcagcc gcttcggcac gcgccagcac gcccgctttg tcggccactt
    98401 ccacacacaa agtatcgaaa tagtgcgcat ggcgcagctt cagacctttt tgttgcaggc
    98461 ccgccgccag gatatcggtc agacggtgga tgcggttagc gatacgtttc aggccaaccg
    98521 gaccgtggta aacggcatac agactggcaa tgtttgccag caagacctgg gatgtacaaa
    98581 tgttggagtt cgctttttca cgacgaatat gttgctcacg agtctgcatc gccatgcgca
    98641 gagcggtgtt gccagctgca tctttcgata caccgataat acggcccggc attgagcgtt
    98701 tgtattcgtc tttcgccgca aagaatgccg cgtgtgggcc accgtagccc atcggtacgc
    98761 caaagcgttg cgccgaacca aaaacaatat ccgcgccctg tttacctggc gcagttaaca
    98821 gcaccagcgc cataatatcg gcggcaacgc tgaccacaat tttgcgtgat ttcagttcgc
    98881 taataagcgc agtgtagtcg tgaatttcac cagtagtgcc gacctgctgt aacagcgcgc
    98941 cgaagacgtc ctgatggtcg agcacttttt gcgcatcatc gacaatcact tcaaaaccaa
    99001 aggtttcggc acgagtacgg accacatcca gcgtttgcgg atgaacgtca gaagcaacaa
    99061 agaagcggtt ggcatttttc agtttgctga cgcgtttcgc catcgccatt gcttcggcgg
    99121 cagcggtggc ttcgtcaaga agagaagcag aggccatatc cagcccggtt aaatccagcg
    99181 ttacctgctg gaagttgagc agtgcttcaa ggcggccctg ggagacttca ggttgatacg
    99241 gagtatacgc ggtataccag cccggatttt ccagcatgtt acgcaggata accggcggta
    99301 gctgcacggc ggtgtaaccc atgccgatgt aagacgtgaa gcgtttattg cgactggcaa
    99361 tagccttgag ttctgccagt gcggcgtatt cggtcgccgg tgcgccaacc tgcggcggag
    99421 tcgcaagctg aatatctttc ggcacaatct ggccggtcag cgcgtttaac gattgtgcgc
    99481 caacggcatt cagcatttct tgctgttgcg cggcgtccgg tccgatatgg cgttcaataa
    99541 aagcgccgct gttttcaagc tggcttaacg tctgtgtcat gagcgatggt tcctgaaacg
    99601 tgcagtgaat tgtgaacctc tctccttacg aagagagtga gggtgaggcg taaatgttcc
    99661 tcaccctgat cctctcccgc agaagaggaa taaagccgtt actcgtcttc taacaatgct
    99721 tcgtatgcgg ttgcatccag cagtgattcc agttcgcttt catcgctggc tttgattttg
    99781 aaaatccagc cgcctgcata cggttcgctg ttgaccagtt ccggagaatc gctcagtgca
    99841 tcgtttaccg ccacgatttc accgcttact ggcgcataaa tatctgacgc cgcttttacc
    99901 gattcggcaa ccgcgcagtc atcgcccgcg ctaaccgttg cgcccacttc cggcaggtca
    99961 acaaacacca tatcgcctaa cagctcctga gcgtgttcgg tgatgccaac ggtgtaagtg
   100021 ccgtcggctt ctttacgcaa ccattcgtgt tctttgctgt atttcagttc tgctggtacg
   100081 ttgctcatca atcaatctcc aaaaaagtaa atcacgcgac ggctttgccg ttacgcacaa
   100141 aaacaggttt cgtcacttta accggcattt cacggttgcg aatttgcaca atcgccgttt
   100201 caccaatacc ttccggcacg cgcgccagcg caatgctata acccagcgtt ggggagaaag
   100261 taccgctggt gataatgcct tcatgctggt tgccctgcgc atcagtaaaa cgtaccggca
   100321 gttcattacg cagcacgcct ttttcggtca tcaccagacc aaccagtttt tctgtgccat
   100381 gttcacgctg cgcttccaga gcttcacgac cgataaagtc acgatctgcc ggttcccagg
   100441 cgatagtcca gcccatattg gcggctaaag gagaaatagt ttcgtccatc tcctggctat
   100501 acaaattcat gcccgcttcc agacgcagcg tgtcacgcgc gcccaggcca catggcttaa
   100561 cgccagcttc caccagcgcg cgccagaaat cggccgcttt ttcattgggc agcgcaattt
   100621 cgtagcccgc ttcaccggtg taaccggtgg tggcaataaa cagatcgccc gcctgcacgc
   100681 caaagaacgg tttcatccct tccaccgcct gacgctgggc gtcattaaac agtgtggcag
   100741 cttttgcctg cgcattcggc ccttgtacgg cgatcatgga aaggtcatca cgaacagtaa
   100801 tttcgatgcc gaaaggttca gcgtgttggg taatccagga gaggtctttt tcgcgggtgg
   100861 cggagttaac aacgaggcgg aagaaatctt cagtaaagta gtagacgatg agatcatcta
   100921 tcacaccgcc agaggcattc aacatccccg agtaaagggc tttgccgctt ttggtgagct
   100981 tcgccacatc gttcgccagc agataacgta gaaactcccg ggtgcggctg ccgcgaagat
   101041 cgacgatggt catatgtgac acatcaaaca ttccggcatc ggtacgtacc gcatgatgtt
   101101 cgtcgatttg cgaaccgtaa tgcagcggca tcatccagcc gtggaaatcc accatgcgag
   101161 cgccgcaaag cgtgtgttgt tcgtacaaag gagtctgttg tgccatcttg tcctcattga
   101221 ataagcgggg ctgacaactt ttctatggcg aaattatcac cacgaaaccc agcatcggag
   101281 ccactcccgg tccccaacgc aatcgttctc ttttgcctga acttaccacc gaaacagact
   101341 gttaaccata aggtaaaatt gatcatcaca ttagcttatg gttaaaaaac gccaaaatcg
   101401 taacagaata aaaaaccaaa aaatgaacaa atctctatat aaagataaat agatgagaaa
   101461 gttaatttga ataagacaac attaagaact aaaaaaatgt caaaaaacac taaatcaaaa
   101521 attcgtggca ttagaaaata taatgcgaaa tcgcaggtga aattagttta tttcaaatga
   101581 ggaaaatctc ccggcgaaaa aaccgggaga tgaaagtgtg atgggtatca aataaacagc
   101641 agaagagaaa tttttaacgc agccattcag gcaaatcgtt taatcccatt gcctggcgaa
   101701 taagttgtgg cttaacgcca ggaagcgtat cagccagttt cagaccaata tcacgcagca
   101761 attttttcgc cggattagcc ccggaaaaca gatcgcggaa tccctgcata ccagccagca
   101821 tcagcgccgc gctgtgcttg cggctacgct catagcgacg caggtaaatg tactgcccga
   101881 tgtctttacc ctgacgatgc aaccgtttca gttcagcaat cagctctgca gcatccataa
   101941 agccgagatt taccccctgc cccgccaacg ggtgaatggt atgcgcggcg tcgcccacca
   102001 gcgccagacg gtgcgcggca aactggcgcg cataacgccc cgttagcggg aacaccaggc
   102061 gctcactttc aaccttgcat aagcccaggc gattatcaaa agcgatattt aacgcgcgat
   102121 taaattcgtc ttcgcctgcc tgctgcatcc gctgcgcttc ctctggcgac agtgaccaga
   102181 caatcgagca aagatgcgga tcgctaagcg gcaaaaaggc cagaatgcct tcgccatgaa
   102241 aaacctgtcg cgccaccgca tcatgcggtt cttccgtgcg aatggtcgcc accagcgcgt
   102301 gatgctgata atcccagaaa gtcagcggaa tatcggcttt gttgcgcaac caggaattag
   102361 cgccgtccgc gccaatcacc agacgcgccg ttaacatgct gccatctttc aacgtcagga
   102421 aggtttcatt ttcaccccag gcgacctgct gtaattctgc gggggccaac agagtgatat
   102481 ctgacgactg cagcgctttg ttccacagcg cgtagtgaat cactgagttt tcaacgatat
   102541 gcccaagatg gctatagccc atgctttgat cgtcaaacga gatgtgacca aagctgtctt
   102601 tgtcccacac ttccatgccg tgatagcaac aggccctacg agagagaatg tcctgccaga
   102661 cgccaagacg ggtgagtaat ttttcgctgg cggcattgat agccgaaacg cgcagttgtg
   102721 gtggtgcatc cgccgccaga ggttccggta cgcgctgctc cagtacggca acgcgtaagc
   102781 cgataccctg taagccgcag gcaaccgcca gcccgaccat gccgccgcca acaatggcta
   102841 catcaacact ttgcattgtt tattccttaa aaccgccttc aacgcgccac ccaaccaaga
   102901 gtgcgctgcg ccagcacatc gcgtgccggg gtaaataatt ccatcgtcat cagcccgatg
   102961 ttgcgcccga caaccagcgg cgtccaacgg ttggcaaaaa gatgtacaag gctgtccgtg
   103021 acgccgatgg ttgcttcgcg atcgcgctgt cgacgctgct gataacggca caatacgccg
   103081 taatcaccca tgtcttctct gcgttcctgc gcctgagtca gggtttctgc aagactcatc
   103141 acatcacgca taccgaggtt aaatccttgc ccggcgatgg gatgcagagt ttgcgccgca
   103201 ttccccacca gcacggtacg atgggtaata ggtttggcgg cgcgggttaa cgccagcgga
   103261 taagcactac gttttccggc gtgggtaatt tgccccagtc gccagccaaa ggccgactgg
   103321 agttcacggc agaacttctc gtcgctccac gacagcacct cttcgcgccg ttccagtgga
   103381 tgacaccaga ccagcgaaca gcgtccgtca gacatcggca acatcgccag cgggccatat
   103441 tgtgtaaagc gttcaaaagc gcgcccttca tgcgcaacgg aagtcgcaac gttggcaatc
   103501 acagccagtt gttcgtaagg ctcctgctgc cagtcaacac cgcacgcggt ggctaacgct
   103561 gaatgggtgc catcagcggc taccagcacg cggcccgtca gcgtctcgcc actctccagc
   103621 gtcacttcaa cgtggctctg agtacgggca acgttagcca cgcgatcagg gcaatgcagc
   103681 gttacgccag gtgctttgcg cagcaatgca aacagccgtt gcccgacatt gtgcaattcg
   103741 acaacctgcc ccagcgccgc cagttggtaa tcttctgcgg cgagggtgac aaatccagcg
   103801 tgaccacgat cgctaacatg cacggtggtg atggcagttg cgcaatcagc cagagattgc
   103861 cagacgccga tgcgcgccag ttgctgacag gtacccgccg ccagcgcaat agctcgtcca
   103921 tcaaagcccg gatgcgcatg tgactctggc gcggtcgctt caatcaaatg tactggcagc
   103981 gccccgtgac ttaaccggga aatagccagc gccagcgtcg cgcccgccat gccgccaccg
   104041 acgatgatta cgctcattgc tttctcgcag ctgccatcaa cgcttcgatt tcttccggct
   104101 ttttcaccac gctggcggtg aggttttcat taccggtttc ggtaatcaca atatcgtctt
   104161 caatacgaat gccgataccg cgatactgtt ctggcacttc tgcatccggc gcaatataca
   104221 gtcctggttc tacggtcagt accatacccg gttccagaat acgcgagcga tcctgaccat
   104281 aaacaccaac gtcatgaaca tccagtccta accagtggct aaggccatgc ataaagaaag
   104341 gacgatgggc gttctgagcg atcagttcat caacatcacc tttcaggatg ccgagtttta
   104401 ccagaccgct aaccatgatg cgcaccactt caccagtgac ttcctgaatg gaagttcccg
   104461 gacgatacag gcgcaggctg gtttcaagag actccagcac aatgtcatag atttcacgct
   104521 gagcctgagt gaatttgccg ttgaccggga aggtgcgggt aatgtcgcca gcgtaacctt
   104581 tgtattcaca acccgcgtca atcaacacca ggtcaccgtc acgcagttca cactcgtttt
   104641 cggtgtaatg caaaatgcag ccgttttcac cgctgccaac aatggtgtta taggaagggt
   104701 aacgcgcacc gtggcggtta aattcgtggt gaatttcgcc ttccagatgg tactcgaaca
   104761 tccccggacg gcatttttcc atcgcccgtg tatgcgccag tgcggtgatt tcacccgcgc
   104821 ggcgaagtac ggcaatctct tctggtgatt tgaacaggcg catttcatga acaacaggac
   104881 gccagtcgat catcgttgcc ggtgcggtga gattttgccg cgaaccttta cgcagtttct
   104941 caagcgcgct gttcacgatt tcatcagcat atgcatattc gccctgggcg tggtaaacca
   105001 catccagacc attaagtagt tgataaagtt gttgattgat ttcgctgaat gccagtgcgc
   105061 ggtcaacgcc cagtttctct ggcgcggcat cctggcctaa gcgacgacca aaccagatct
   105121 ctgccgtcag gtcgcgaacg cggttaaaca aaacgctgtg gttatgagtg tcatcgcttt
   105181 taatcagcac cagcaccgct tccggttcgt taaagccggt gaagtaccag aagtcactgt
   105241 tctgacgata ggggtattcg ctgtcggcgc tacgtgttac ttctggtgca gcaaaaatca
   105301 gcgcggcgct gccgggttgc atttgctcta ccagggcctg acggcgacgc tgaaattctt
   105361 gccgggatat atcactcata acactctcct tacgtttttt gtttttagtg tagagtcggt
   105421 ttttgtactt ctggcgcggt cggttgcgga tgagtaaagg tgtcgtggca taacagcgcg
   105481 gcaacacgga cgtactcgat gatctcttca agcgacattt caagctcttc ctgatcttcg
   105541 tcttcgtcgt aacccaactg cgcgatgtta cgcagatcgt cgatggcttc accggtttcg
   105601 ccggtcactt tgtccagctt cggttgcgta acgccaagac caagcaggaa gtgattgacc
   105661 caaccagcca gcgcatcagc ccgatcgaaa acgctgacat catcgccatc aggtagataa
   105721 agctgaaaaa ggaagccgtc atcctgcagg gcatcgctgg tggcagagtg cattttgcgc
   105781 agtgcctgtg ccagctcatg accgaaagcc atgccttcgt tcgtcaggtc gtgaagtagc
   105841 ggcagccatg agctgtcatc gttaccgcca catatcatcc cactgattaa accatgcatc
   105901 tcagcagggg tcagacccgt cccttgttgg ttcagatact ggttcatttc gttgtaacca
   105961 ggcatttcgt tctgtataga cataagcatt cgtcgtcaaa gggaggaata ttcatgatat
   106021 gctaccactt tgggccctgg tggaccagaa aagggcttgt ctcttctcat cagggtagct
   106081 atagtgtcgc cccttcgcag accatgggtc taaagacgaa ggcagcgcag tcaatcagca
   106141 ggaaggtggc atgtctgcac aacccgtcga tatccaaatt tttggccgtt cactgcgtgt
   106201 gaactgcccg cctgaccaaa gggatgcgtt gaatcaggca gcggacgatc tgaaccaacg
   106261 gttgcaagat ctgaaagaac gcactagagt cacaaatact gaacagttgg tcttcattgc
   106321 cgcactgaat atcagctatg agttagcgca agaaaaagcg aagactcgtg actacgcggc
   106381 aagtatggaa cagcgtattc ggatgctgca gcagaccata gaacaagcgt tacttgaaca
   106441 aggtcgcatc accgaaaaaa ctaaccaaaa ctttgaatga cacttttcgg tttactgtgg
   106501 tagagtaacc gtgaagacaa aatttctctg agatgttcgc aagcgggcca gtcccctgag
   106561 ccgatatttc ataccacaag aatgtggcgc tccgcggttg gtgagcatgc tcggtccgtc
   106621 cgagaagcct taaaactgcg acgacacatt caccttgaac caagggttca agggttacag
   106681 cctgcggcgg catctcggag attcccttct tatctggcac cagccatgac gcaattacca
   106741 gaactcccac tgacattatc ccgacaagaa atccgcaaaa tgattcggca acgtcgtcgt
   106801 gcgttaacgc cggaacaaca gcaggaaatg ggtcaacaag ccgctacccg gatgatgact
   106861 tatcccccgg tggtgatggc acatacggtc gctgtattcc tctcttttga tggcgaactc
   106921 gacacccagc cactcataga acaactctgg cgcgccggta agcgcgtata tcttccagtt
   106981 ttgcatccct ttagtgccgg taatttgctg ttcctgaatt accatccaca aagcgaactg
   107041 gtgatgaaca agttgaagat ccatgagcca aaactggatg tgcgtgacgt gctacccctt
   107101 tcccgattag acgtgttgat tacaccgctg gtcgcctttg atgagtacgg tcagcgcctg
   107161 ggaatgggcg gtggttttta tgatcggacc ttacaaaact ggcagcacta taaaatgcaa
   107221 ccggtgggtt atgcgcatga ttgtcagttg gtggaaaaac tccccgttga agagtgggat
   107281 atcccactgc ctgcggtggt tacaccgtcg aaagtctggg agtggtgagg gcgacacacc
   107341 tgcatcgccc tgattgacat cgttgattct ttaacctaat ttagtgagta agggtaaggg
   107401 gggattgctc ctcccctgtg actgactgtt aataagcgct gaaacttatg agtaacagta
   107461 caatcagtat gatgacaagt cgcatcataa cccttctcct tcaagccctc gcttcggtga
   107521 gggctttacc gttacagccc tgtacagtcc cgccatcgta aatccccatt aaataaacac
   107581 aacgcattga tctgactttg atttattttc tggagcagac tcgcaaagta gaatgcgcaa
   107641 cgcggcaacg gtgtggagaa gggataaaat aacgggcaag tcagtgacct gcccgttgat
   107701 tttcagagaa agggatttag tatagcagac gggcgcgaat ggtacccgga atagctttca
   107761 ttgcctgcag cgctttttcg gcaacgtctt cgtcggcttc aatatcaata actacataac
   107821 ccatctgggc ggaagtttgc agatattgcg cggcgatgtt gacgccctgc tcggcaaaaa
   107881 ttttgttgag cgcagtcagc acacccggac ggttttcgtg gatgtgcatc agacgacgac
   107941 caccgtgcag tggcagcgag acttccggga agttcaccgc agagagcgtt gaaccattgt
   108001 cagaatactt gatcaattta cccgcaactt ccaggccaat attctcctgc gcttcctgag
   108061 tcgaaccgcc aatgtgtggc gtcagaagga cattgtcgaa ttcacacagc ggagaggtaa
   108121 atggatcgct attggtcgcc ggttccgtcg ggaatacgtc gattgccgcc cccgccagat
   108181 gtttgctcgc cagcgcgtca cacagcgctg gaatatccac cacagtaccg cgcgaagcat
   108241 taatcagcag cgagccgggt ttcattagcg aaatctcttt cgcgcccatc atatttttgg
   108301 ttgacggatt ctctggtaca tgcagactca ccacatcgct catattcagc aggtcagaaa
   108361 gatgctgtac ctgagtggcg ttgcccagcg gcagtttgtt ttcaatatca taaaagtaaa
   108421 catacattcc cagcgattca gccagaatgc ccaattgcgt accaatatga ccgtagccga
   108481 tgatacccag ctttttgccg cgcgcttcaa aagaacccgc cgccagtttg ttccacacgc
   108541 cacgatgcgc tttagcattg gcttccggca cgccgcgcaa tagcagcagc agttcgccaa
   108601 tcaccagctc cgcaacagag cgcgtatttg agaacggtgc gttaaatacc gggatcccgc
   108661 gctttgccgc cgcatccaga tcaacctggt ttgttccgat acagaaacag ccaatagcga
   108721 ccagtttttc tgcggcgttg atcacgtctt cagtcagatg ggtacgggat cgcaggccga
   108781 tgaagtgggc atcgcggatg gattctttta attgttcatc atccagcgcg cctttgtgaa
   108841 attcgatgtt ggtgtaacca gctgcacgaa ggctttccag cgccttttgg tgcacgcctt
   108901 ctaccagcag aaacttaatc ttgtctttct ccagcgatac ctttgccatt tacccaatcc
   108961 tgtcttttga aatgttgtgt gcggatttgc atccgccttt caacatatca aaaaataata
   109021 ttgcggcaat atgaacgttt gcgtcgcgat gttgaggaaa tatcacgcaa aagtatttct
   109081 tggatgaata tgctggttta gaggatttat ttagagcaat cgacaattgc ctggtaaaaa
   109141 cgtgacacat gtcaccaaat ttaatgaaga gaattttttt aacgggggag gttcccccgt
   109201 cagatcattt cacaatagtt ttgacaccgt caggtgtgcc aatcagcgca acgtccgcgc
   109261 cacggttagc aaacaaacca acagtcacca cgccaggaat cgcatttatg gcgttttcca
   109321 tcgctatcgg gtcaaggatt tccatgccgt ggacgtcgag gatcacgttg ccgttatcgg
   109381 tcactacgcc ctgacggtat tccggacgac cgcccagttt caccagctgg cgcgccactg
   109441 cactacgtgc catcgggata acttctactg gcagcgggaa tttgcccaga atatcaacct
   109501 gcttggaagc gtctgcaata cagataaatt tttccgcaac cgaagcaatg attttttcac
   109561 gggtcagcgc cgcgccgccg cctttgatca tttgcatgtg gccgttgatt tcatctgcgc
   109621 catcaacgta gatgccaagg ctgtcgactt cgttgagatc aaaaacgtga atgccgaggc
   109681 ttttcagttt ttcagtggaa gcatctgaac tggaaacggc cccttcaatc tggcctttca
   109741 ttgtaccgag tgcgtcaata aagtgtgcgg cggtggaacc tgtacctaca ccaacaatgg
   109801 tgccgggctg aacatactga agtgccgccc atcctactgc ttttttcaat tcatcctgcg
   109861 tcatgatcgt ttcgcctgtg gtatgaaatt tcacacgcat tatatacaaa aaaagcgatt
   109921 cagaccccgt tggcaagccg cgtggttaac tcatccataa aatatcgcgc aatggcgggc
   109981 atcccttttc gccccgcaaa taaagcatac aacggtctgg gtatgccgct ccacggtgcg
   110041 aacaggcgca ccagttcccc gttcgcaagc ccctgtttac aggcaaactg aggcaataac
   110101 gccacgccat tcaacacaac cagggcgcga actcgctgag cgaaatgcat tagcgcaaat
   110161 ctctgatctt ttaagctgcg cgttaaccac tgatacaaat gttacccgcc aacggcttcg
   110221 gtatatgcaa cccgacacaa aattgtgtca tagtgcagga aaaagcattt accaggagca
   110281 gacaacagca atgaaacgcc cggactacag aacattacag gcactggatg cggtgatacg
   110341 tgaacgagga tttgagcgcg cggcacaaaa gctgtgcatt acacaatcag ccgtctcaca
   110401 gcgcattaag caactggaaa atatgttcgg gcagccgttg ttagtgcgta ccgtaccgcc
   110461 gcgcccgacg gaacaagggc aaaaactgtt ggcgctacta cgccaggtgg agctgctgga
   110521 agaagagtgg ctgggcgatg aacaaaccgg ttcgactccg ctgctgcttt cactggcggt
   110581 caacgccgac agtctggcga cgtggttgct tccggcactg gctcctgtgt tggctgattc
   110641 gcccatccgc ctcaacttgc aggtagaaga tgaaacccgc actcaggaac gtctgcgtcg
   110701 cggcgaagtg gtcggcgcag tgagtattca acatcaggcg ctgccgagtt gtcttgtcga
   110761 taaactcggt gcgctcgact atctgttcgt cagctcaaaa ccatttgccg aaaaatattt
   110821 ccctaacggc gtaacgcgtt cggcattact gaaagcgcca gtggtcgcgt ttgaccatct
   110881 tgacgatatg caccaggcct ttttgcagca aaatttcgat ctgcctcctg gcagcgtacc
   110941 ctgccatatc gttaattctt cggaagcgtt cgtgcaactt gctcgtcagg gcaccacctg
   111001 ctgtatgatc ccgcacctgc aaatcgagaa agagctggcc agcggcgaac tgattgactt
   111061 aacgccaggg ctatttcaac gccggatgct ctactggcac cgctttgctc ctgaaagccg
   111121 catgatgcgt aaagtcactg atgcgttgct cgattatggt cacaaagttc ttcgtcagga
   111181 ttaatccatc aaataacgcc tgatagcaca tatcaggcgt tatcctcact tctttttgta
   111241 ttccttgaat cacatcgcaa aatagacaaa tctcaggcgg caaaaaacga cgtctgaatg
   111301 catttttttg ctggcgacaa acccacgtaa aaagctcacc gtaagcgcaa ataccctcat
   111361 tttgattgcg ttttacggag caaataatgt ctaacgtgca ggagtggcaa cagcttgcca
   111421 acaaggaatt gagccgtcgg gagaaaactg tcgactcgct ggttcagcaa accgcggaag
   111481 ggatcgccat caagccgctg tataccgaag ccgatctcga taatctggag gtgacgggta
   111541 cccttcctgg tttgcccccc tacgttcgtg gcccgcgtgc cactatgtat accgcccaac
   111601 cgtggaccat ccgtcagtat gctggtttct cgacagcaaa agagtccaac gctttttatc
   111661 gccgtaacct ggccacccac cgaggctacg actccgataa cccacgcgtg gcgggcgacg
   111721 tcggcaaagc gggcgtcgct atcgacaccg tggaagatat aaaagtcctg ttcgaccaga
   111781 tcccgctgga taaaatgtcg gtttcgatga ccatgaatgg cgcagtgcta ccagtactgg
   111841 cgttttatat cgtcgccgca gaagagcaag gtgttacatc cgataaactg accggcacca
   111901 ttcaaaacga tatcctcaaa gagtatcttt gccgcaacac ctatatttac ccaccaaaac
   111961 cgtcaatgcg tattatcgca gacatcatcg cctggtgttc cggcaacatg ccgcgattta
   112021 ataccatcag tatcagcggt taccacatgg gtgaagcggg tgccaactgc gtgcagcagg
   112081 tagcatttac gctcgccgat aggattgagt acatcaaagc agcaatctcc gccgggctga
   112141 aaattgatga cttcgcccct cgcctgtcgt ttttcttcgg cattggcatg gatctgttta
   112201 tgaacgtcgc catgttgcgt gcggcacgtt atttatggag cgaagcggtc agtggatttg
   112261 gcgcacagga tccgtataac aacgttatcc gcaccaccat tgatcattgt gcacatccca
   112321 tgtatcggga ttatctgcat cgatatctgg aaaatgcgtc cggcggacat attcaccacg
   112381 atcttagcca cgtcttcgac ttacaccgta atttaattgc aaccggatcg atgctgggtt
   112441 aatggtttgt cccgtcacga tcttcagcaa tatgctgaag catcgtggcg gtataacgat
   112501 gatttctgat tgaataaaga tattcctgca tatacatcgg cctgtgcggc gcatcaaaat
   112561 atttcagcgt tgccggattc accagtcgcc aggcaaaatg cgggatcacc gtcagaaaat
   112621 gtccccgctc cacggcgctg attttagcca taaaactata gggacgataa ataatggttg
   112681 gattgatccc acaaggacgc atattcgcat caatcattgc ttcgaagtta gcccggtttt
   112741 gaaagcgcat ttgtagctag ggcagctcct gaagcagctc ttgctcctgt cgcccttcat
   112801 aacggcgaga aacgagaaag cccaatcgca gcggtggtag ttcactgata gtcaggtttt
   112861 ccagttcctg aactcgtgca gatacatgct gtggggagat aataaaatct aactgacggt
   112921 caaaaagatt atcgataacg ccattttcgc tgaactcaac tggctggatg gtcacgcctt
   112981 cgtacttatc tccgagacta atcaactgat caaaaataat tgtcggataa gtattatcta
   113041 tgcctatcac aatttctcgt taacgacgtc ctgagttatg gatttcatta tcaatcgcag
   113101 aaagtcgttg ataaaccggg aacagttttt gatacagttc ctgtccggct ttattgaggc
   113161 tgatattatt atctttgcgg gtaaatagcg tatagccaat ttgttcttcc agcgcggcaa
   113221 tgcttttgcc aaatggcgaa gccgtcatat ggattttttc tgccgcccgg gcaatattat
   113281 tggtttgcgc taataaaatg aaattgcgca tctttttcga aataaaaatg tccatccccc
   113341 ctctcccgca tccttgtccg cttaaccgtt tcagtcagcc tatccttgat gaaaccgcga
   113401 gcaaagatag gtgattacgt catggtttta cagaaaatta cagaaaaagg aggcaatatc
   113461 gggtaaaggc attagcccga cgaatacgtc gggctacaag tattattgtg ctgcaggtgt
   113521 tttagcaggt tgttgatcca caggttctaa ctggaagact acatcgacct gatcatcaaa
   113581 ctgaatagcg gcctgctcgt aagtttcctg tgcggacacc ggtgcagcat cagctttcat
   113641 catccgcacc attgggctgg gctgatagtt ggaaacatgg tagcgcacgc tatataccgg
   113701 ccccagttta cgattaaagc cattcgccag ttcctgtgcc tgatgaatcg cgttatcaat
   113761 cgctgcctta cgcgctttgt ctttataggc atccggctgc gccacgccca gcgacacaga
   113821 acgaatttcg ttaagacccg cctttagcgc gccgtccagc aaggaattca gtttgtctaa
   113881 ctgacggagc gtgacttcca ccgttctcac tgcgcggtag cctttcagga tacttttacc
   113941 atcctgataa tcataatctg gctgagtgcg taagttcgct gagctgatat cttttttcgc
   114001 gatctgattg agctcaagga aggaaatgta ttgtgcgacg cgctcatctg cctgtttctt
   114061 ggcagtagcg gcatccttcg cggccacgtt aacttcaatc gcaagagtgg caatgtctgg
   114121 caccgcatcc acgcttgccg taccggaggt gacaatatgc ggtccatccg gcaattcgtt
   114181 agcctgcgct gccatcccgc taatacccat taatgccgcc agggcgataa ctttgaactt
   114241 cacgttagtc tctccgtgtt aattgacttg cccaaaattc aggacctctg gaggcaagct
   114301 tagcgcctct gttttatttt tccatcagat agcgcctaac tgaacaaggc ttgtgcatga
   114361 gcaataccgt ctctcgccag ctgcaaggca ataaaccaca taacacatcc cactaccaga
   114421 ttgataatgc gctgtgattt tgccgtgcgc aggcgcggtg ccagccaggc tgcgagaata
   114481 gccagaccaa agaaccacag gaaagaggcg ctaattgtcc cgagcgcaaa ccaacgtttt
   114541 ggttccacat caagttgccc gccaaggctg cccagcacaa caaaagtatc caggtaaaca
   114601 tgcggattca gccaggtcac tgccaacatg gtggcgataa ttttccatct gccttgtttc
   114661 aggacttcgg cactggctaa ctcaatgtta ctgctcattg ctgttttaaa agcgccaaaa
   114721 ccataccaca gcaagaaggc tacgccgccc caggtgacca gcgccagcaa ccacggcgac
   114781 tgcatcaata acgcgctgcc accaaaaatc cccgcacaaa tcaggaccaa atcgctgata
   114841 gcacaaagta aggcaatcat aatgtggtac tgacgacgaa tgccctgatt catcacaaaa
   114901 gcattttgtg gaccgagcgg taggatcata gccgccccaa gtgcaagacc ttgaaagtaa
   114961 taagaaaaca cgttagatat tccgaattaa gtatctgatg cagagactat atcgcgggat
   115021 tgttattagc ggaaattgat aatattaatt ggcaatcaga aaaactaata agagagaggc
   115081 cagagagtat tatctggcct cagcgttgat tacgcagctt tgtcttcttt cacccgctta
   115141 aagttcacat ccatttgcgg atacgggaag ctgataccgg cggcatcaaa ttcacgttta
   115201 atacgctcca gcacatccca gtacacgttt tgcagatcgc cgctgttgct ccagactcgg
   115261 accacgaaat taatcgacga tgcaccaagt tcgttcagac gcacagtcat ttcgcgatct
   115321 ttcaaaatgc gatcttcaga ctggataata tcggtcagga tctgcttaac ctgatcgata
   115381 tcggaatcat acgccacgcc aataataaat tcgttacggc gagctggctc gcgggagaag
   115441 ttaataatat tcccggcaat aattttacca ttcggaataa cgataatttt accgtctgca
   115501 gtacgcatgg tggtggagaa aatctgcaca ctcagcacag tgccggctac gccgccgagg
   115561 tcaacatatt caccggcacg gaacgggcgg aacatgacaa gtaacacgcc agcggccagg
   115621 ttagacagtg acccctgcaa agccagacca acagctaagc ctgcggcacc gagtacagca
   115681 atgactgacg ctgtttgtac gcccacgcgc cccagtgcag cgattagcgt aaaggcgata
   115741 attccgtaac ggactaatgc agaaagaaaa tcagcaacag tggcatcgat tttacgggag
   115801 atcatcaggc gattcaccgc gttggaaatc atccgcgcga taatcaaacc aacgatgatg
   115861 atcgcgagtg ccgccacgat gtttactgca taacttagca gcagcgcctg gttagccacc
   115921 agccagcttc ccgcgccgtt tatgctatcg acaacattca aatcttccat tcaatattcc
   115981 ttttcaactg actcaaaatg gagaaataca ctccgccgcc ttatggcggg cagtctgaca
   116041 agggtaaaca ataaagcata attttgccaa atagatcaca gatttctcat ctgcatcacc
   116101 ttgcttttgg cgaaaaaaag acccgcagag cgggccttga gataagcaga aaagaatgac
   116161 ttacagaacg tcgatcgcgt tcagttcctg gaatgctttt tccagacgag cgatcatcga
   116221 agtctgaccg gcacgcagcc atacgcgcgg atcgtagtat ttcttgttcg gctgatcttc
   116281 gcctttcggg ttacccagct gaccctgcag gtaagcttcg ttcgctttgt agtagttcag
   116341 aacgccttcc caggttgccc attgggtatc ggtatcgatg ttcattttca ctacgccgta
   116401 gcttacggag tctttgattt cctgagcagt agaaccggaa ccaccgtgga atacgaagtt
   116461 caggctgttg tgcggcaggt tgtgtttctt agaaacatat tcctgagagt cgcgcaggat
   116521 ggtcggagtc agaacaacgt tacccggctt gtaaacaccg tgtacgttac cgaaggacgc
   116581 tgcgatggtg aaacgcgggc tgattttgct cagctcggta tacgcataat caacgtcttc
   116641 cggctgggtg tacagtgcag aagcgtccat gtggctgttg tccacgccgt cttcttcacc
   116701 accggtgcaa cccagttcga tttccagagt catgccgatt ttggacatgc gctccaggta
   116761 tttagagcag atttcgatgt tctcttgcag agattcttca gacaggtcga tcatgtgaga
   116821 agagaacagc ggcttgccgg tagctgcgaa gtgtttttca cccgcgtcca gcagaccgtc
   116881 gatccacggc agcagtttct tcgcgcagtg gtcggtgtgc aggataaccg gaacaccata
   116941 atgttcagcc atctggtgaa cgtgatgcgc accagagatc gcgcccagga tagcagcacc
   117001 ctgcggaacg tcagatttca cgcctttacc agcgataaag gaagcaccac cgttggagaa
   117061 ctgaacgata accggcgctt taactttagc agcggtttcc agcacggcgt tgatggagtc
   117121 agtaccgacg cagtttactg ctggcagtgc gaagttgttt tcttttgcta cctggaaaac
   117181 tttctgtacg tcatcaccag tgattacgcc aggttttacg aaatcaaaaa tcttagacat
   117241 gtctcttgtc ctgtatcgtc gggccttata ctcgtcatac ttcaagttgc atgtgctgcg
   117301 tctgcgttcg ctcaccccaa tcacttactt atgtaagctc ctgggattca ctctcttgtc
   117361 gccttcctgc aactcgaatt atttagagta tgaaaaagtg cgtgctctaa aagcgcgctg
   117421 aaacaagggc aggtttccct gccctgtgat tttttacttc ttagcgcgct cttcgagcat
   117481 cgctactgca ggcagtactt taccttccac gaattcgagg aatgcgccgc cgccagtgga
   117541 gatgtaggag attttgtcag caatgccgaa caggtcgatt gctgccagag tgtcgccgcc
   117601 gccagcgatg gagaacgctt cgctgtctgc gatagcgtta gccacgattt cagtaccttt
   117661 gcggaagttc gggaattcga acacgccaac cggaccgttc cacagaatgg ttttcgcatt
   117721 cttcaggatt tcagccagtt cctgagcgga agcatcaccg atatccagga tctgctcgtc
   117781 agctttcaca tcgttaacag atttcagggt agccggtgca gtttcagaga actcggttgc
   117841 tacgcgaaca tcagacggaa ccgggatgtt gcaggtggtc agcagacgtt tagcttcgtc
   117901 aaccaggtca gcttcgtaca gggatttacc cacatcgtgg ccttgtgccg caataaaggt
   117961 gttagcaata ccaccaccaa cgatcagctg gtcagcgatt ttagacaggg agtccagaac
   118021 ggtcagtttg gtagatactt tagaaccacc aacgatagcc accatcgggc gagcaggttc
   118081 tttcagtgct ttacccagcg cgtccagttc agctgccagc agcgggcctg cgcacgcaac
   118141 gtcagcgaat ttaccgatac cgtgagtaga agcctgcgcg cggtgagcag taccgaatgc
   118201 gtccattacg aacacgtcac acagtgcagc gtattttttg gacagagttt cgtcgtcttt
   118261 cttctcgcct ttgttgaagc gaacgttttc cagaacaacc agttcacctt cagcaacgtc
   118321 aacgccgtcg aggtaatctt taaccagacg aaccgggtta gacagtttgt ctttcaggta
   118381 gttaacaacc ggcagcagag agaattcttc gttgtactcg ccttcggtag gacgacccag
   118441 gtgggaagtt accatcactt ttgcgccttg tttcagggcc agttcgatgg tcggcagaga
   118501 agcacggata cgcgcgtcgc tggttacttt cccgtctttt actggtacgt tcagatccgc
   118561 acggataaat acacgtttcc cagcaagatc cagatcggtc atcttaatta cagacatggt
   118621 gaatcctctc gttgattcta aaagttttgt agacgctgct tgcgtcttac ctgaaagcaa
   118681 cagtagccat agctaacgtc gtgtcgagca ttcggttagc aaagccccat tcgttatcgc
   118741 accagaccaa cgttttgatc aggtgtgcgc cactgacccg ggtttgagtg ccatcgacaa
   118801 tggcactgtg cggatcgtgg ttaaaatcta cagagaccaa cggcaattcc gtatagtcaa
   118861 ctataccatg aaatgcacct tgtgctgctt tttgcagcaa caggttgact tcattggctt
   118921 ttacaggttt cttcaccgtc acgcttaaat cgattgccgt cacatttatg gttggcacac
   118981 gtaccgcaat cgcctcaaag cgatcgttaa attgcggaaa aaatcgtgtg ataccggcgg
   119041 ccagtttagt atcgaccgga atgatcgact gactggctgc ccgagtgcga cgcaggtcag
   119101 gatggtatgc atcaataacc tgttgatcat gcatggcgga gtgaattgtg gtcacagtgc
   119161 cagactcaat accgtacgca tcatctaaca atttgatgac gggaattatg caattcgtgg
   119221 tacaggaagc attagaaacg atgcggtgtt ccgcacgaag ttgatcctga ttgacgccat
   119281 aaacaacggt cgcgtcgaga tcgttactgc caggatgtga aaagagcact tttttagccc
   119341 cggcggcaat gtgtgcttca ccatgctcgc gggagccata tacgccggtg cagtcgagga
   119401 ctacatcaac gccaagttca cgccagggga gcgattgcag tgaacgttca tgcaatacac
   119461 ggatggcgtc atcaccaaca aaaagttgat cgcgttcctg tcgtacttcc catgcaaaac
   119521 ggccatggct ggtgtcatat ttcaacaaat gcgccatgcc cgcagcatcc gccagttcgt
   119581 tgattgccac cacggtaatt tccgcacggc gtccggattc atacaaagca cgaaccacat
   119641 tacgcccgat gcgaccgaag ccatttatcg ctacgcgtac ggtcatagat ctcctgcaag
   119701 gttttccctg agcaaatttg ccagacagag taatccagca aatcgttcgg ggaaacctta
   119761 cctgtcgcaa actgcgactg attggttaat tgtcgaacat ttaatcgact gaaacgcttc
   119821 agctaggata agcgaaacgt ggaataaaag gaatgtttgt ccagtcaaag aagacaatta
   119881 tctgacttat gtcacgtttt catccccgcc cctgtggaat ttattccact ttgcagaatc
   119941 acgaataagc gtagcaatat cttttcgttg tgcggtcaca aaccctgact tatatcagaa
   120001 tatgactgat gcagcgtcga tattatccgc aatacgtccg agtttcggag tactccaatg
   120061 atgacattgc cctacccata ttcttcctcc gcacgctttt acgcgctgcg cctgctcccc
   120121 gggcaggaag ttctctccca attacgcgcc ttcgcgcagc aacaacaact tcacgccgcg
   120181 tggattgcag gttgtaccgg cagtctgact gacgtcgcct tacgctatgc cgggcaagaa
   120241 aacactgccc tgctaagcgg taagttcgaa gtcatcgcat tgaacggcac gctggaacag
   120301 agtggtgaac atcttcatct ctgcgtttcc gatccacacg gcacgatgct tggcggtcat
   120361 atgatgcccg gctgtaccgt gcggaccacg cttgaactgg tgatcggctg ccttgaggaa
   120421 ctggcgttta gccgccagct ttgcgcgctt tctggttacg acgagttgca tatttccccc
   120481 gttaaataac tattttcaga gaggttttct tatggcgcgt cgccactttt ccagtcaggc
   120541 actggtgttg atcgttatct ctatcgccat caatatgatc ggcgggcaac tggccagcat
   120601 ggttaaatta cctatttttc tcgactccat cggcacactt attagcgcgg tactgcttgg
   120661 tccgataatc gggatgctga ccggtttact gaccaattta ctctggggat tgctgaccga
   120721 cccgatcgcc gccgcatttg cgcccgtcgc gatggtcatc ggcctggtcg ccggttggct
   120781 ggcgcgagcg ggttggtttc gcaccctgcc aaaagtcgtt gttagcggcg tgattattac
   120841 gcttgcggta acggtcgtcg ctgtaccgct gcgtactgcg ctgttcggcg gcgtgacagg
   120901 aagcggagcc gatttgttcg ttgcctggat gcactcgatg gggcaaaacc tggtggagtc
   120961 ggtggcgatt acggtgatag gcgcgaacct ggtcgataaa attcttacag cggtgatagt
   121021 ctggctttta ctgcgtcagc tgccgattcg caccacgcgc cattttccgg caatggctgc
   121081 cgtgcgctaa atgcatcctt ttacatcctt aacgctgtgg gcgctggcgg cctgcaccac
   121141 gcttatcctg cctacacaga caatattgcc agtctatagc gcggcgacct ttttctgcct
   121201 tattgcgcta aaggccacgc ggcggcgggc aaaatatgtc gtctggctga tgttctcgct
   121261 gggggctgga ctgtggctgg tgcacggtgg ctggctgaca gaatggctaa gcggcacgcc
   121321 acactctcca gaacggtggg cgcatgctat tacgctctgg ttgcggattc tggcgattgt
   121381 ttcaacctca cagttgtgga tgcagtacgt ccccgtgcaa cgttttatcc gcgctttgtt
   121441 tgcttctcgc ctgccgccgg gcgtcgctta tctgtttgcc gggccgttat tggtcgttga
   121501 gcagttaaaa cggcaattgg cgattattca tgaagcgcag tgcgcccgcg gcgtgccgct
   121561 ggatgagggc tggtatcagc gtttacgtgc gatgcccgcg ttaattattc cgctaacaca
   121621 caatgcgcta aacgatcttg ctgtccgtgg tgcggcgctg gatatgcggg catttcgaat
   121681 caacaatagg cgcactacgt tatgggcacc agccgatagc accctacaat gcgtagcacg
   121741 ttacgccatg atattgctaa tgctggctga attcggagcg tggatatggt tacgttagaa
   121801 cagtttcgct attgcccgac acactcaacg catcctccgt tctgttatga ctttcactat
   121861 gtcaaaccgg ggatggtcgc catctttggt gacaacggca gtggcaaaag tacgctggca
   121921 cagctgatgg cgggctggta tccggacttt ctaccaggag agataaccgg cacggggacg
   121981 cttctcggta cgcccattgg gcgtctcccg cttaatgaac aatccgccac catccagctc
   122041 gtccagcaat cgccctattt gcagctctcc ggctgtacct ttagcgtgga agaagaagtt
   122101 gcctttgggc cagaaaatct gtgtcttgct gaaaaagaga ttatggcgcg gattgacgcc
   122161 gccctggccc tgaccgagtg ccagccgttg cgccatcgtc acccggcaac actctccggt
   122221 ggagagacac agcgtgtggt catcgcctgc gccatcgcga tgcagccaaa gctcttaatt
   122281 cttgatgaag cctttagccg cctgacgccg caggcccgcg aaatgctgtt gcagcgctta
   122341 caacactggg cgcttgaacg tggttcgctg attattcttt ttgaacgtca tcacacacct
   122401 ttcctgaacc actgccagca agcgtggcaa ttgcaaaacg gagcgctcca gccactatgt
   122461 taacgttaaa tcagatatct tatcgctggc ctggcgcggc tacggattgt ctttgcgaca
   122521 tttctctgca actcaaacaa ggtgaatggc tggcgctgac cggcgacaat ggcgcgggaa
   122581 aatcgacgct gttacgagta atggcaggtc ttcttacgcc cacagccggt acggttatgc
   122641 tgcaacaaca agcgatgaaa aacctgaaaa accgccagcg cgcggcaaag attggcgtac
   122701 tgtttcagga agcggaaaat cagctttttc acagcaccgt tgctgacgaa atcgcatttg
   122761 gtttgatact gcaaaaatgc ccggcggatg aaatcactca acgtaccaat gctgccctgc
   122821 aatgctgtca gttagcagac actgccagcg cgcatccgtt agatctgcat agtgcgcagc
   122881 gacggatggt cgccgtcgcc tgcctggaag cactctctcc gccactattg ctactggacg
   122941 agccgagtcg ggattttgac gaaaattggt tgagcgtgtt tgaaagctgg ctggaaaagt
   123001 gccgccagcg aggcacgagc gtcgtagcaa tcagtcatga cgccgcattt acccggcgtc
   123061 atttctctcg tgtggtgcga ctggaagatg gtgtaatcag gaacgttaat ccatcagacg
   123121 atattcaccc gtagcggtca tcattaaggt caaatttgca ggcagactct cttccagcac
   123181 ccggcgaaca ttcggcccgt cggtacggtc ataaaaggct tctgcgtctg ccagcgataa
   123241 ccctcccgcc agcttgcgcc ccaccagacg ctcccgcaac gcagatgcgg gagctttgat
   123301 aaagatcgag aaatcacaaa attgcgcaag ctggcaccac ttctcgtcgt ccaacaacaa
   123361 ccagtttcct tcgacgatga cgagtggtgc ggtaacgtgc aacacatctt caacaggatc
   123421 atgcttttgt cgatcgtact gcggccacgt acaatcccct tccacaaccc ggcacagatt
   123481 ttccgccagt ttcgcaacgt tgaatgtctc tggtgcgcct ttgaagggtc gcaattgatg
   123541 cacatccagc cagctattgt aatggtgaaa accatccatc ggcagcgtct gaatagcggg
   123601 cagttccggg tcttgttgcg cgagatattc ccagaaggtg gttagggtag atttacccgt
   123661 ccccggcgga gcgcaaagaa aaaccaccgt acgccgctgc ggatttactg tctgtaaggc
   123721 cgccagcata cgcagcaatg gtttatgtac attttcaatt tcatcatcag agtactgcgc
   123781 ctgtaccttt agtccattca ccgtcagttc gattttcacg gcgttaattc ctttaaggtg
   123841 gtcgttactg ccagcgtcag cgccgttttg accatcccgc taaaacgcgc ctctgaccag
   123901 acggcgaaat cggcgaactt catcgctttc aacgcgtcat agagcgtcgc attgcgggtt
   123961 atgctattga cgttgctgat aaaatcccag gttatgtcat cagcaaatct gggcgtttca
   124021 tcctgttcgt tcaggtaatg ccaaaactgg gaaaaatgcg tgatatcggc gtacagccat
   124081 ttatccattt tccccagcgc ataaatcaaa cgcagcgcaa catcaatatc gtcaagcggg
   124141 ccgctttggg cgagtaacgg cttcactgca tattcgacga tctcttcatc gttatcgaca
   124201 aacagcgacg gcagaaactg gcgtatcccc tggagcaaaa tagaatgcgc agttttcata
   124261 aatgaaaata aattgtcctg tgcattcagt tgctcaagca catcatcttc tgtcagcgtc
   124321 gccattggtc ttccgataga tcaccatcaa tgcagggagt ctattatatt acacgtttgg
   124381 tccgcgccgc cgatcagtaa tgtctgcgtc cgcaccccat tcgccgtctg ttggataccg
   124441 ttcaccaact cgccgcccgt cacgcccgta gcgctaaaga ggatatcgtt ccccctcacc
   124501 agttcatcga gcgagtatac acggttaacg tcaacgccca ttgccttgca acgcttgcgc
   124561 tcctgctctg caatctgccg attttccgtg taatcccctt tagcctgaca aaagtcaatc
   124621 agctcggcct gcatatcccc gcctaatgct ttaacggcac aggcagaaat aacaccttcc
   124681 ggtgcgccac cgatggtgta catcacatcg taaggattat cctgccagca agtcagcacg
   124741 ctggcggcga catcgccatc cggcagggca aaaaccttca cgccgagctg tgttgcttcc
   124801 tcaattgcgg cactcaggcg cggtttatcc agcgtaacca tgcgcagctt gtccagcggt
   124861 ttacctaacg cccgcgccac gttacgcaag ttgtccgcca gaggcaaaga cagatctatc
   124921 gccccggcag ccagtcgatt aacaaccagc tttttcatat acatatcggg cgcatgtaac
   124981 aggctatctc gaggggcgaa agccatgacc gccagcgcat tgctctgccc catcgccacc
   125041 atccgcgtgc cttcaatggg atcgaccgcg atatcgactt ctggcccatc gcctttgccc
   125101 acctcttcgc caatccacag catcggcgca tggtcaattt ccccctcgcc gataaccact
   125161 cgcccacgaa aagcaacgtc gtttaatgcc tggcgcatcg cggtgaccgc aaggccatca
   125221 attttatttt tgtcgccaca gccggtttgc ggccaggcag ccaacgctgc ctgttccgta
   125281 acgcgaaata atggccacgc cagggacatc attgcgcggc ctccccaata tcaacgccaa
   125341 attgtgccag cagatatttc tcggcctgtt cattccagat accgtgcgtt ttctcaacca
   125401 gccgcgccag ctctttaaac agcggatcgg ttttgccttt ttcggcaaaa tcggcaatgg
   125461 cggtcagcgg catggtcacg ccgttataaa tgagtttttt accgccaggg atatccggca
   125521 gattgagcac ggtttctggc accgcatcca ggccaccaat atgggtcacc ataaacgacg
   125581 gctgtaactg ccccgtggcg ctaagggcaa tcgcctcttt catgtcgtcc gtggaaccgc
   125641 cagacgtgcc gacaatgtgc gtactgttgt aatggacgtt gtagaaatta aacggcactt
   125701 tgaagttttt atccgtcgga ccggcaaaga agttcaggca gccatcttca gccagtaatt
   125761 catcagccat ctcgacgact gaaggcaccg ctgcatagac aaatacgtca tcaaatccgg
   125821 catcatccgt cagcgcccgc agcgtctgga ccggatcgct catccctttg gtattcatat
   125881 acaccagctc aatgccttta ctggccgcca gctccaccgg cagcaacttc tgcacctgcg
   125941 ccagccgttt gtcgtcgata tcgactacca ccacccgcgc cggttgtatg ccgccgttaa
   126001 tggcgtaatc gatagcgcca atgcccatcg ggccagcaca cgccagcagg gcaatattgc
   126061 cgccaggttt gacgcccata cgatgctcat aaacatattg cgtggtgtga taattggcat
   126121 gataagcacc aataatgcag cacataggct ctgccagcga cgccgcagca aaataagagc
   126181 cgtgatacgg taatacacag cctaaattaa tcgcgatttc gggaataatc atataggtgg
   126241 cattgccacc aaaatattcg tagctgtatc cggctgaata tccgcttggt agccccatcg
   126301 ccggttgcaa tacaaaacgc tgcccttttt tatatttgcc agtgagattt ttacccactt
   126361 cgacaacaac cccagcacat tcatgcccgg taataaccgg atgattttct aaatcgtcgg
   126421 ggacgcgttt atgttcacta ccaagcaacg ccgctttcca ggtggataaa caaacgctgt
   126481 cagaaattac actcactaac agttcattat cagtaatttc tggcagttca aattcgcgca
   126541 gacggacatc ccgcttgcca taaatagcag caactttggt tttcattttt acctctgtaa
   126601 tcagtgttta tgttcagcgg ttaattgatt aaataaagtg tcgagttttg gatcgccaat
   126661 atagttatta atcaatatca gtggtttatc cgtcacacgt ttcacgcgcc cttccagact
   126721 ggcgtgagta acgacgatat ccgcatccgc aggcacgttt tctatggcgt aatgttttac
   126781 ttctattgcc agccccgctt tttccaggcg tttacggaag gtggttgcgc ccatcgcact
   126841 ggagcccatc cctgcatcgc aaacaaaggc aatacgctta acacggctta acgagaatgc
   126901 accttcttgt ttcatcgcct taaccgcatt ggctgactcg gtaaactcat cttcgctctt
   126961 cgtttccacc gttttttcca tcttcagtat cagcgaagtg atagcaaagg acaccagggt
   127021 acctaccgta acaccggcaa ttgtcgccag gaacgagcct ttcggcgtca gtgccaggta
   127081 agcaaagata gaccccggac ttgggccagc caccagacca ccgtccagta agttaaacat
   127141 ccaggtgcca gacataccgc ccgcaatcat ggcaataatg gtcagcggct tcatcagcac
   127201 atacgggaaa tacagttcgt ggatcccacc gaggaagtga ataatcatcg ccccgggcgc
   127261 agaacgttta ctcatccctt taccaaacaa ggtaaacgcc agcagcagcc ccagaccagg
   127321 acctgggttg gaggccacca tgaagaagat ggatttaccg ttaaccgaag cctgttgcat
   127381 tcccagcgga taatagacgc cctgatcaat cgcattatta aggaaaagca ctttcgccgg
   127441 ttcattgatg actgacagca aaggcagata acccgcatgt accagcgcct caatacactc
   127501 tttgacgaaa gtattagcaa ttaacaccgc cggaccgata acttcaaaac ccagcagaca
   127561 aaagagcatc cccgcgatac ctaatgagaa gttattgata accatctcaa aaccagcagg
   127621 tatgcgtttt tccagcgact tgtcgatata tttaatcacc agaccaccga gcggccccat
   127681 aatcatcgag ccaaggaaca tcgggatttc agcgccgacg atcacaccaa tcgtaccaat
   127741 tccgcccatg accgcgccgc gtttaccgcc gaccagatga ccaccggtag aaccaatcat
   127801 cacgggcaat aaataggtaa tcatcggacc aacaattttg gcgaaatgtt cattcggcag
   127861 ccagccggtg ggaataaata atgccgttat aaatccccag gcaataaaag caccgatatt
   127921 ggggatgacc attgcagtca aaaagccccc aaaagcctgg acctttgcac gagcagactt
   127981 gttttccata atattatcct gtagaggaga gagtaattat ccgcggctga taatgtccgc
   128041 taattgtttt tctgatgatg ctgttaagag ttgttcgagt atttcttctt cgcacagtaa
   128101 ttcacttaac gcctgaatag cgccaatgtg cgaattggca tcggcagcag aaagcccgat
   128161 gagtaattta atcggttcgt ccttccccgg gaaataaacg ccttgtttaa gtaacgtcaa
   128221 agacatcccg gttttaagcg ccccacattc cggtcgcgca tgaggcattg ccacgcctgg
   128281 tgcgagaata taataaggac cattgctgat ggtggagtct ttaatagatt gaatgtaatt
   128341 ctcgctgata tagtttttat ccagcaatga tgccatcgag aaatcgatag cttcctgcca
   128401 gtcttttgct gaatgtataa ctgagattga tgattctgga aaataatcaa taagccgcat
   128461 aaattatcct tattttattt ttagggtacc gtccggcggt aaaaataaaa tactcgtgca
   128521 gtttaatgaa agcaattggg cacgcg
//
LOCUS       DAPOXO010000003        99986 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPOXO010000003 DAPOXO010000000
VERSION     DAPOXO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 99986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99986
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.003"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            31..1320
                     /gene="uraA"
                     /locus_tag="ROH59_000300"
     CDS             31..1320
                     /gene="uraA"
                     /locus_tag="ROH59_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDX4802840.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKLISMLRPEEVVLDAEDADITDK"
     gene            1370..2116
                     /gene="hda"
                     /locus_tag="ROH59_000301"
     CDS             1370..2116
                     /gene="hda"
                     /locus_tag="ROH59_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HDX4802841.1"
                     /translation="MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSS
                     LLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVP
                     EVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
                     GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRT
                     LFMTLDQLDRASITAQRKLTIPFVKEILKL"
     gene            complement(2254..2613)
                     /gene="arsC"
                     /locus_tag="ROH59_000302"
     CDS             complement(2254..2613)
                     /gene="arsC"
                     /locus_tag="ROH59_000302"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311384.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HDX4802842.1"
                     /translation="MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAAT
                     LRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSEEALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPEQVLEIVG"
     gene            complement(2634..4097)
                     /gene="bepA"
                     /locus_tag="ROH59_000303"
     CDS             complement(2634..4097)
                     /gene="bepA"
                     /locus_tag="ROH59_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HDX4802843.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANDAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            4310..5371
                     /locus_tag="ROH59_000304"
     CDS             4310..5371
                     /locus_tag="ROH59_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDX4802844.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQD"
     gene            complement(5469..5939)
                     /gene="bcp"
                     /locus_tag="ROH59_000305"
     CDS             complement(5469..5939)
                     /gene="bcp"
                     /locus_tag="ROH59_000305"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDX4802845.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            complement(5939..6511)
                     /locus_tag="ROH59_000306"
     CDS             complement(5939..6511)
                     /locus_tag="ROH59_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HDX4802846.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            6657..7535
                     /gene="dapA"
                     /locus_tag="ROH59_000307"
     CDS             6657..7535
                     /gene="dapA"
                     /locus_tag="ROH59_000307"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDX4802847.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            7552..8586
                     /gene="bamC"
                     /locus_tag="ROH59_000308"
     CDS             7552..8586
                     /gene="bamC"
                     /locus_tag="ROH59_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HDX4802848.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSEWHELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            8799..9512
                     /gene="purC"
                     /locus_tag="ROH59_000309"
     CDS             8799..9512
                     /gene="purC"
                     /locus_tag="ROH59_000309"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDX4802849.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            9680..10543
                     /locus_tag="ROH59_000310"
     CDS             9680..10543
                     /locus_tag="ROH59_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HDX4802850.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            10558..12573
                     /gene="tmcA"
                     /locus_tag="ROH59_000311"
     CDS             10558..12573
                     /gene="tmcA"
                     /locus_tag="ROH59_000311"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HDX4802851.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEERWCFDHALKLRDALP
                     GDWLWISPQPDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWDEWENQPDADSLRWSDCPDPIATPHFVQHFKRVLTANNDAILWRQNQPFSL
                     AHFTPRTDWHPATGAPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAG
                     SAIVTAPAKAATDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLYQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHTPQGNIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGGNEIAGALWLVDEGGLSQELSQAVWAGFRRPRGNLVAQSLAAHGSNPLA
                     ATLRGRRVSRIAVHPTRQREGTGRQLIAGALQYIHDLDYLSVSFGYTEELWRFWQRCG
                     FVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQWNGEMLPVD
                     PLNDAVLSDDDWLELAGFAFTHRPLLTSLGCLLRLLQTSELALPALRGRLQKNASDAQ
                     LCTTLKLSGRKLLLVRQREEAAQALFALDDVRTERLRDRITQWQFFH"
     gene            12647..13345
                     /gene="ypfH"
                     /locus_tag="ROH59_000312"
     CDS             12647..13345
                     /gene="ypfH"
                     /locus_tag="ROH59_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDX4802852.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARVNAIMPTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMALESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(13426..13626)
                     /locus_tag="ROH59_000313"
     CDS             complement(13426..13626)
                     /locus_tag="ROH59_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HDX4802853.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(13654..14781)
                     /gene="dapE"
                     /locus_tag="ROH59_000314"
     CDS             complement(13654..14781)
                     /gene="dapE"
                     /locus_tag="ROH59_000314"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HDX4802854.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFINELVAIE
                     WDQGNDFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(14785..15141)
                     /locus_tag="ROH59_000315"
     CDS             complement(14785..15141)
                     /locus_tag="ROH59_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HDX4802855.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNG
                     FINELGWEALLNTRGTTWRKLDETTRNKITDAASAATLMTEMPAIIKRPLLCAPGKPM
                     LLGFSESSYQQFFHEV"
     gene            15522..15581
                     /gene="ypfM"
                     /locus_tag="ROH59_000316"
     CDS             15522..15581
                     /gene="ypfM"
                     /locus_tag="ROH59_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HDX4802856.1"
                     /translation="MIERELGNWKDFIEVMLRK"
     gene            complement(15680..18793)
                     /gene="acrD"
                     /locus_tag="ROH59_000317"
     CDS             complement(15680..18793)
                     /gene="acrD"
                     /locus_tag="ROH59_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HDX4802857.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVA
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(18957..20657)
                     /gene="narQ"
                     /locus_tag="ROH59_000318"
     CDS             complement(18957..20657)
                     /gene="narQ"
                     /locus_tag="ROH59_000318"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HDX4802858.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQM
                     SSELHKLYRSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGDNWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            20863..22842
                     /gene="aegA"
                     /locus_tag="ROH59_000319"
     CDS             20863..22842
                     /gene="aegA"
                     /locus_tag="ROH59_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HDX4802859.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDAALSGMAKSRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRAD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVAVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLNSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRRPVPVEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            22910..23485
                     /gene="nudK"
                     /locus_tag="ROH59_000320"
     CDS             22910..23485
                     /gene="nudK"
                     /locus_tag="ROH59_000320"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HDX4802860.1"
                     /translation="MTQQITLVKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNAKKKTVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPEVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDSQRANAGGGVEDEDIEVLELPF
                     SQALEMIKTGEIRDGKTVLLLNYLQMSHLMD"
     gene            23611..24654
                     /locus_tag="ROH59_000321"
     CDS             23611..24654
                     /locus_tag="ROH59_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HDX4802861.1"
                     /translation="MRYRIFLLFFFALLPMSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQMIQEGRAITLRDGNQTISLSGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSL
                     DPLRREVNVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPQASRPVRLRLPFNNGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(24731..26734)
                     /gene="tkt"
                     /locus_tag="ROH59_000322"
     CDS             complement(24731..26734)
                     /gene="tkt"
                     /locus_tag="ROH59_000322"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDX4802862.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVVHEIDGH
                     DPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEKYRESVLPSNVSARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(26754..27704)
                     /gene="tal"
                     /locus_tag="ROH59_000323"
     CDS             complement(26754..27704)
                     /gene="tal"
                     /locus_tag="ROH59_000323"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDX4802863.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            27993..30272
                     /gene="maeB"
                     /locus_tag="ROH59_000324"
     CDS             27993..30272
                     /gene="maeB"
                     /locus_tag="ROH59_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HDX4802864.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRNDR
                     MPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
     gene            30565..30900
                     /gene="eutS"
                     /locus_tag="ROH59_000325"
     CDS             30565..30900
                     /gene="eutS"
                     /locus_tag="ROH59_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HDX4802865.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
     gene            30913..31392
                     /gene="eutP"
                     /locus_tag="ROH59_000326"
     CDS             30913..31392
                     /gene="eutP"
                     /locus_tag="ROH59_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HDX4802866.1"
                     /translation="MKRIAFVGTVGAGKTTLFNALQGNYTLARKTQAVEFNDNGDIDT
                     PGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            31367..32068
                     /gene="eutQ"
                     /locus_tag="ROH59_000327"
     CDS             31367..32068
                     /gene="eutQ"
                     /locus_tag="ROH59_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HDX4802867.1"
                     /translation="MKKLITANDIREAHARGELAMSVVLRASIITPEAREVADLLGFT
                     ITECDESIPVTASVPASASADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGALQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            32065..32868
                     /gene="eutT"
                     /locus_tag="ROH59_000328"
     CDS             32065..32868
                     /gene="eutT"
                     /locus_tag="ROH59_000328"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HDX4802868.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLGFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLGE
                     QAIVGLSDEDLHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVTKQPLTVKQIQQRLGETQ"
     gene            32865..33881
                     /gene="pta"
                     /locus_tag="ROH59_000329"
     CDS             32865..33881
                     /gene="pta"
                     /locus_tag="ROH59_000329"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDX4802869.1"
                     /translation="MIIKRCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLVE"
     gene            33920..34213
                     /gene="eutM"
                     /locus_tag="ROH59_000330"
     CDS             33920..34213
                     /gene="eutM"
                     /locus_tag="ROH59_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDX4802870.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            34320..34607
                     /gene="eutN"
                     /locus_tag="ROH59_000331"
     CDS             34320..34607
                     /gene="eutN"
                     /locus_tag="ROH59_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HDX4802871.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPQGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            34619..36022
                     /locus_tag="ROH59_000332"
     CDS             34619..36022
                     /locus_tag="ROH59_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HDX4802872.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPPAAVHEMGVFASLDDAVAAAK
                     VAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGPTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNLAIVAAGGPENLLVTVTNPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQSVLLKNIDERGKGTVSRDWVGRDAAKIA
                     AAIGLKVPEQTRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            36033..36869
                     /gene="eutJ"
                     /locus_tag="ROH59_000333"
     CDS             36033..36869
                     /gene="eutJ"
                     /locus_tag="ROH59_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HDX4802873.1"
                     /translation="MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGDEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCMQPGVAALFCKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLY
                     AK"
     gene            36859..38046
                     /gene="eutG"
                     /locus_tag="ROH59_000334"
     CDS             36859..38046
                     /gene="eutG"
                     /locus_tag="ROH59_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HDX4802874.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAVLTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGQSLPKAVGYGHDLVARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQIGRALRTKKSDDRD
                     AINAVSELIAEVGINKRLADVGATTGHYGAWAQAAQEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            38263..39489
                     /gene="eutH"
                     /locus_tag="ROH59_000335"
     CDS             38263..39489
                     /gene="eutH"
                     /locus_tag="ROH59_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDX4802875.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVLIVAVLVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKEDASAAKTEAEAQS"
     gene            39486..40889
                     /gene="eutA"
                     /locus_tag="ROH59_000336"
     CDS             39486..40889
                     /gene="eutA"
                     /locus_tag="ROH59_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDX4802876.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKTLILEQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSRSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGPGTDARSLTGAQL
                     AQVTRRMAELIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDETDLVSAWQQALIQLDLCPKTDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            40901..42262
                     /gene="eutB"
                     /locus_tag="ROH59_000337"
     CDS             40901..42262
                     /gene="eutB"
                     /locus_tag="ROH59_000337"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HDX4802877.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCILAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPS
                     LFF"
     gene            42283..43170
                     /gene="eutC"
                     /locus_tag="ROH59_000338"
     CDS             42283..43170
                     /gene="eutC"
                     /locus_tag="ROH59_000338"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit beta"
                     /protein_id="HDX4802878.1"
                     /translation="MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCAAPVTSESCA
                     LDLGSAEAKAWIGVENPHHADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            43180..43839
                     /gene="eutL"
                     /locus_tag="ROH59_000339"
     CDS             43180..43839
                     /gene="eutL"
                     /locus_tag="ROH59_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDX4802879.1"
                     /translation="MPALDLIRPSVTAMRVIASVNAEFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVANIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            43852..44352
                     /gene="eutK"
                     /locus_tag="ROH59_000340"
     CDS             43852..44352
                     /gene="eutK"
                     /locus_tag="ROH59_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311336.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HDX4802880.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVKEPD
                     APVIVAESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            44398..45450
                     /gene="eutR"
                     /locus_tag="ROH59_000341"
     CDS             44398..45450
                     /gene="eutR"
                     /locus_tag="ROH59_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HDX4802881.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGELGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEEAQPMMTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMREWG"
     gene            complement(45456..46355)
                     /gene="hemF"
                     /locus_tag="ROH59_000342"
     CDS             complement(45456..46355)
                     /gene="hemF"
                     /locus_tag="ROH59_000342"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HDX4802882.1"
                     /translation="MKPDAHLVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVY
                     PRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVE
                     RRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPKDGSPEAALSEFIKVRDWV"
     gene            complement(46359..47228)
                     /gene="amiA"
                     /locus_tag="ROH59_000343"
     CDS             complement(46359..47228)
                     /gene="amiA"
                     /locus_tag="ROH59_000343"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HDX4802883.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKEEPLKTSNG
                     HSKPKAKKSGGRRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYF
                     HWFDNQKAHSRKR"
     gene            47442..47867
                     /locus_tag="ROH59_000344"
     CDS             47442..47867
                     /locus_tag="ROH59_000344"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HDX4802884.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLSPWNDPEMDIERKMNHDVSL
                     FLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            47854..48303
                     /locus_tag="ROH59_000345"
     CDS             47854..48303
                     /locus_tag="ROH59_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HDX4802885.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRASFPRIWHVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEEKE"
     gene            48364..48939
                     /locus_tag="ROH59_000346"
     CDS             48364..48939
                     /locus_tag="ROH59_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HDX4802886.1"
                     /translation="MKSLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGNNVAMVINGDQG
                     TISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADSDDNRAVECKAEGSQHISY
                     QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            49035..49934
                     /gene="yfeX"
                     /locus_tag="ROH59_000347"
     CDS             49035..49934
                     /gene="yfeX"
                     /locus_tag="ROH59_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HDX4802887.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            complement(50112..51536)
                     /gene="murP"
                     /locus_tag="ROH59_000348"
     CDS             complement(50112..51536)
                     /gene="murP"
                     /locus_tag="ROH59_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HDX4802888.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KARQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIECMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVSGFIFTTLFGCRNVNLD"
     gene            complement(51540..52436)
                     /gene="murQ"
                     /locus_tag="ROH59_000349"
     CDS             complement(51540..52436)
                     /gene="murQ"
                     /locus_tag="ROH59_000349"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDX4802889.1"
                     /translation="MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHTQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSSTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLD
                     AAEAKKCLDQHGGFIRKALEKE"
     gene            52716..53507
                     /gene="ucpA"
                     /locus_tag="ROH59_000350"
     CDS             52716..53507
                     /gene="ucpA"
                     /locus_tag="ROH59_000350"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416921.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HDX4802890.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DEDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPM
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            53665..54681
                     /gene="cysP"
                     /locus_tag="ROH59_000351"
     CDS             53665..54681
                     /gene="cysP"
                     /locus_tag="ROH59_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HDX4802891.1"
                     /translation="MAVNLLKKNSLVLVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMGKLKDKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRK"
     gene            54681..55514
                     /gene="cysT"
                     /locus_tag="ROH59_000352"
     CDS             54681..55514
                     /gene="cysT"
                     /locus_tag="ROH59_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HDX4802892.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLAQMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            55514..56389
                     /gene="cysW"
                     /locus_tag="ROH59_000353"
     CDS             55514..56389
                     /gene="cysW"
                     /locus_tag="ROH59_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HDX4802893.1"
                     /translation="MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            56379..57476
                     /gene="cysA"
                     /locus_tag="ROH59_000354"
     CDS             56379..57476
                     /gene="cysA"
                     /locus_tag="ROH59_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HDX4802894.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPLTVVMHGDDAPQRGD
                     RLYVGLQHARLYNGDERIETRDEELALAQSA"
     gene            57611..58522
                     /gene="cysM"
                     /locus_tag="ROH59_000355"
     CDS             57611..58522
                     /gene="cysM"
                     /locus_tag="ROH59_000355"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HDX4802895.1"
                     /translation="MSTLEQTIGNTPLVKLQRMAPDNGSEVWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPAEYLP
                     GIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(58525..58893)
                     /locus_tag="ROH59_000356"
     CDS             complement(58525..58893)
                     /locus_tag="ROH59_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HDX4802896.1"
                     /translation="MKKIICLVVTLLMTLPAYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCDEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKMPGKSDE
                     NAQPFLHALIAQTDKTVPAQ"
     gene            58998..59849
                     /gene="pdxK"
                     /locus_tag="ROH59_000357"
                     /gene_synonym="thiJ"
     CDS             58998..59849
                     /gene="pdxK"
                     /locus_tag="ROH59_000357"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HDX4802897.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKDCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGKALTDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            complement(59892..60401)
                     /gene="crr"
                     /locus_tag="ROH59_000358"
     CDS             complement(59892..60401)
                     /gene="crr"
                     /locus_tag="ROH59_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDX4802898.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(60442..62169)
                     /gene="ptsI"
                     /locus_tag="ROH59_000359"
     CDS             complement(60442..62169)
                     /gene="ptsI"
                     /locus_tag="ROH59_000359"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HDX4802899.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIIIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            complement(62214..62471)
                     /gene="ptsH"
                     /locus_tag="ROH59_000360"
     CDS             complement(62214..62471)
                     /gene="ptsH"
                     /locus_tag="ROH59_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HDX4802900.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            complement(62855..63826)
                     /gene="cysK"
                     /locus_tag="ROH59_000361"
     CDS             complement(62855..63826)
                     /gene="cysK"
                     /locus_tag="ROH59_000361"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDX4802901.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            complement(64011..64772)
                     /gene="cysZ"
                     /locus_tag="ROH59_000362"
     CDS             complement(64011..64772)
                     /gene="cysZ"
                     /locus_tag="ROH59_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HDX4802902.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            65002..66000
                     /gene="zipA"
                     /locus_tag="ROH59_000363"
     CDS             65002..66000
                     /gene="zipA"
                     /locus_tag="ROH59_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HDX4802903.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEVARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPRPTQPVQQPVQQPAYQPQPEQPLQQPVSPQVASAPQPVHSA
                     PQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLN
                     SIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQV
                     PSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            66071..68086
                     /gene="ligA"
                     /locus_tag="ROH59_000364"
     CDS             66071..68086
                     /gene="ligA"
                     /locus_tag="ROH59_000364"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDX4802904.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLMQFKAWGLPVSDRVTLCESAEEVLAFYHKVEKD
                     RPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPEPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDETEMLRLLGS"
     gene            68088..68306
                     /locus_tag="ROH59_000365"
     CDS             68088..68306
                     /locus_tag="ROH59_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HDX4802905.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKIEGLTQLVQPLKRPL"
     gene            complement(68303..69301)
                     /locus_tag="ROH59_000366"
     CDS             complement(68303..69301)
                     /locus_tag="ROH59_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HDX4802906.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEQLQAQQESSADKA"
     gene            69391..70317
                     /locus_tag="ROH59_000367"
     CDS             69391..70317
                     /locus_tag="ROH59_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4802907.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFVLHDRPQQWVMESIRQGDVDFGIVIDPGPVGDLQCE
                     AILSEPFFLLCHRDSALAVEDYVPWQALQGAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAEALWDVVRDQGNALMAGREGDPLYQI"
     gene            complement(70356..71120)
                     /locus_tag="ROH59_000368"
     CDS             complement(70356..71120)
                     /locus_tag="ROH59_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802908.1"
                     /translation="MKKHLFTLTLSSVLAIPAVSHAEFKGGFADIGIHYLDWTSRTTE
                     KSSTKSHKDDFGYLELEGGANFSWGEMYGFFDWENFYNDRHDKPGSEQRYTFKNTNRI
                     YLGDTGFNLYLHAYGTYGSANRVNFHDDMFLYGIGYNFTGSGWWFKPFFAKRYTDQTY
                     YTGDNGYVAGWVAGYSFMLGSEKFTLTNWNEYEFDRDATYAAGNGGKEGLNGAVALWW
                     NATSHITTGIQYRYADDKLGEDFYQDAIIYSIKFNF"
     gene            71369..72202
                     /gene="xapA"
                     /locus_tag="ROH59_000369"
     CDS             71369..72202
                     /gene="xapA"
                     /locus_tag="ROH59_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HDX4802909.1"
                     /translation="MYQAQFSHNPLYCVDIIKTYKPDFTPRVAFILGSGLGALADQIE
                     NAVAISYEKLPGFPVSTVHGHAGELVLGYLQGVPVVCMKGRGHFYEGRGMTIMTDAIR
                     TFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDERFGERFFSL
                     ANAYDAEYRALLQKVAKEEGVPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCELKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI
                     A"
     gene            72263..73519
                     /gene="xapB"
                     /locus_tag="ROH59_000370"
     CDS             72263..73519
                     /gene="xapB"
                     /locus_tag="ROH59_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine/proton symporter XapB"
                     /protein_id="HDX4802910.1"
                     /translation="MSIALRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVY
                     SSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVN
                     AMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSL
                     QLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMVAWTLRFGFFAYGDPSPTGFILLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWHTIWLMFAGYAL
                     FLAVIFFFGFKYNHDPEKITHRSVTH"
     gene            73572..73730
                     /locus_tag="ROH59_000371"
     CDS             73572..73730
                     /locus_tag="ROH59_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1427 family protein"
                     /protein_id="HDX4802911.1"
                     /translation="MKDILFSSGVGFGIGALFTIVRLPIPVPNVLPGILSIVFMYVGY
                     LVVKYFMP"
     gene            73771..74655
                     /gene="xapR"
                     /locus_tag="ROH59_000372"
     CDS             73771..74655
                     /gene="xapR"
                     /locus_tag="ROH59_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XapR"
                     /protein_id="HDX4802912.1"
                     /translation="MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKE
                     LENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARVEQIGRGEAGRIELG
                     VVGTAMWGRMRPVMRRFLRENPNVEVLFREKMPAMQMALLERRELDAGIWRMATEPPT
                     GFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQV
                     GFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKERIPADLYIVY
                     ETQQVTPALVKLLAALAQ"
     gene            complement(74766..74841)
                     /locus_tag="ROH59_000373"
     tRNA            complement(74766..74841)
                     /locus_tag="ROH59_000373"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(74806..74808),aa:Lys,seq:ttt)
     gene            complement(74846..74921)
                     /locus_tag="ROH59_000374"
     tRNA            complement(74846..74921)
                     /locus_tag="ROH59_000374"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(74886..74888),aa:Val,seq:tac)
     gene            complement(74968..75043)
                     /locus_tag="ROH59_000375"
     tRNA            complement(74968..75043)
                     /locus_tag="ROH59_000375"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(75008..75010),aa:Val,seq:tac)
     gene            complement(75088..75163)
                     /locus_tag="ROH59_000376"
     tRNA            complement(75088..75163)
                     /locus_tag="ROH59_000376"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(75128..75130),aa:Val,seq:tac)
     gene            75422..76837
                     /gene="gltX"
                     /locus_tag="ROH59_000377"
     CDS             75422..76837
                     /gene="gltX"
                     /locus_tag="ROH59_000377"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDX4802913.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLTAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALAFIAERENQQ"
     gene            complement(76888..77280)
                     /locus_tag="ROH59_000378"
     CDS             complement(76888..77280)
                     /locus_tag="ROH59_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416898.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDX4802914.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLLEAEEPLAEYAPGIRTPAYRQIISAIDNMTH
                     SEQEKVAQFLSREGIRNFLARLDIDESA"
     gene            complement(77282..77641)
                     /locus_tag="ROH59_000379"
     CDS             complement(77282..77641)
                     /locus_tag="ROH59_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDX4802915.1"
                     /translation="MFKERMTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKA
                     RLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLL
                     REGIIGLLQRLGIRDSK"
     gene            77862..77937
                     /locus_tag="ROH59_000380"
     tRNA            77862..77937
                     /locus_tag="ROH59_000380"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:77895..77897,aa:Ala,seq:ggc)
     gene            78144..80333
                     /locus_tag="ROH59_000381"
     CDS             78144..80333
                     /locus_tag="ROH59_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HDX4802916.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVVLIQLSRLISPLAVIHSNYIFL
                     AWMPLCVMLSILFIFGWRGVVPILCGMFCTNLWNLHLTFLQTAVMIGSQAFAVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVAPIGIKCSMYLVGNFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLSKEKRAFTLS
                     WLAALSVLLLLMCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVLTEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSIYRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGHFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYYISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD"
     gene            complement(80383..81585)
                     /gene="nupC"
                     /locus_tag="ROH59_000382"
     CDS             complement(80383..81585)
                     /gene="nupC"
                     /locus_tag="ROH59_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HDX4802917.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            81921..83159
                     /locus_tag="ROH59_000383"
     CDS             81921..83159
                     /locus_tag="ROH59_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDX4802918.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWV
                     IVVLVVALNIWLLVGTALGL"
     gene            complement(83300..83626)
                     /locus_tag="ROH59_000384"
     CDS             complement(83300..83626)
                     /locus_tag="ROH59_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDX4802919.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
     gene            complement(83741..84997)
                     /locus_tag="ROH59_000385"
     CDS             complement(83741..84997)
                     /locus_tag="ROH59_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HDX4802920.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQR
                     LPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSNEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVFVLGIGGFILGILGVIGG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            85201..86166
                     /gene="glk"
                     /locus_tag="ROH59_000386"
     CDS             85201..86166
                     /gene="glk"
                     /locus_tag="ROH59_000386"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HDX4802921.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEGIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            86385..86711
                     /locus_tag="ROH59_000387"
     CDS             86385..86711
                     /locus_tag="ROH59_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-like phosphotransferase enzyme IIB
                     component 1"
                     /protein_id="HDX4802922.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAAGIIKEIEEM
                     IASEQQ"
     gene            86733..87980
                     /locus_tag="ROH59_000388"
     CDS             86733..87980
                     /locus_tag="ROH59_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDX4802923.1"
                     /translation="MAIKKRSATVVHGASGAAAAVKNPQASKSSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPADIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            87995..89080
                     /gene="ypdF"
                     /locus_tag="ROH59_000389"
     CDS             87995..89080
                     /gene="ypdF"
                     /locus_tag="ROH59_000389"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDX4802924.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISR
                     ESAHILVDSRYYADVEARTQGYQLHLLDAMHTLATIVRQIIADEQLQTLGFEGQQVSW
                     ETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSE
                     CEIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFNVYQIVLQAQLAAISVIRPGVRCQQVDDAARRV
                     ITEAGYGKFFGHNTGHAIGIEVHEEPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAVPKTVLLTGEA"
     gene            89080..90117
                     /gene="ypdE"
                     /locus_tag="ROH59_000390"
     CDS             89080..90117
                     /gene="ypdE"
                     /locus_tag="ROH59_000390"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDX4802925.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILREEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQSVRITTR
                     EECKIPGLLDSDRQGNDVSAMRVDIGARSCDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQSD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMEQLLSALIQRLT
                     RETVVQLTDFR"
     gene            90142..92637
                     /gene="ptsP"
                     /locus_tag="ROH59_000391"
     CDS             90142..92637
                     /gene="ptsP"
                     /locus_tag="ROH59_000391"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDX4802926.1"
                     /translation="MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTLAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRVIPASAQDSTLLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRHLMAEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKLTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTAAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFAPEED
                     VRPLLALENIFVDQSFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLVKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(92640..93497)
                     /locus_tag="ROH59_000392"
     CDS             complement(92640..93497)
                     /locus_tag="ROH59_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4802927.1"
                     /translation="MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPTSLPVGSL
                     CIDFPRLDIVLRGEYGNLLEAKQQRMVEGEMLFIPARAANLPVNNKPVLLLSLVFAPT
                     WLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
                     LHLCRNVVNMPPGNSQPRGDFLYHSICNWIQDNYAQLLTRESVAQFFNITPNHLSKLF
                     AQHGTMRFIEYVRWVRMAKARMILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTP
                     GEYSARFQG"
     gene            complement(93510..94244)
                     /gene="ypdB"
                     /locus_tag="ROH59_000393"
     CDS             complement(93510..94244)
                     /gene="ypdB"
                     /locus_tag="ROH59_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator YpdB"
                     /protein_id="HDX4802928.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSCSKVKEFRQLMHL"
     gene            complement(94259..95956)
                     /gene="ypdA"
                     /locus_tag="ROH59_000394"
     CDS             complement(94259..95956)
                     /gene="ypdA"
                     /locus_tag="ROH59_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     YpdA"
                     /protein_id="HDX4802929.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAMTNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            96333..97571
                     /gene="alaC"
                     /locus_tag="ROH59_000395"
     CDS             96333..97571
                     /gene="alaC"
                     /locus_tag="ROH59_000395"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HDX4802930.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
     gene            complement(97636..97707)
                     /gene="ypdK"
                     /locus_tag="ROH59_000396"
     CDS             complement(97636..97707)
                     /gene="ypdK"
                     /locus_tag="ROH59_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HDX4802931.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(98064..98984)
                     /gene="lpxP"
                     /locus_tag="ROH59_000397"
     CDS             complement(98064..98984)
                     /gene="lpxP"
                     /locus_tag="ROH59_000397"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HDX4802932.1"
                     /translation="MFPKCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GTMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVSALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLYITPEMEGYPTDENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            99337..99579
                     /locus_tag="ROH59_000398"
     CDS             99337..99579
                     /locus_tag="ROH59_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HDX4802933.1"
                     /translation="MIYLWMFLALCIVCVSGYIGQVLNMVSAISSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            complement(99656..99931)
                     /locus_tag="ROH59_000399"
     CDS             complement(99656..99931)
                     /locus_tag="ROH59_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX4802934.1"
                     /translation="MKVNLMLFSLFLFVSIMACNVFAFSISGGGSEASYKETEKTSVM
                     TTTHSTKLQPSQAILFKMREDAPPLNLTEDITPTYPTKANYLIHPLR"
BASE COUNT        23473 a        25136 c        27207 g        24170 t
ORIGIN      
        1 cctataacac ataatacaga ggataatact atgacgcgcc gtgctatcgg ggtgagtgaa
       61 agaccgccac ttttacagac aatcccgctt agtttgcaac atttgttcgc catgtttggt
      121 gcaaccgtcc tggtgcccgt cttatttcat attaacccgg cgactgtact gttatttaac
      181 ggtataggaa cactgctgta tctcttcatc tgtaaaggga aaattccggc ttatcttggt
      241 tccagctttg cctttatttc accggtattg ttactgttgc cgttggggta tgaagtcgcg
      301 ctgggcggct ttattatgtg cggcgtgctg ttctgcctgg tttcttttat cgtgaagaaa
      361 gcggggaccg gctggctgga cgtgctgttt ccacctgcgg caatgggcgc aatcgttgcc
      421 gtcatcggtc tggagctggc gggcgtagct gccggtatgg cgggtttact cccggctgaa
      481 gggcaaacgc cagactccaa aaccatcatc atctctatta ccaccctggc ggtcacggtt
      541 ttaggttccg tgctgtttcg tggtttcctg gcaattatcc cgattttaat tggcgtgctg
      601 gtggggtacg cgctctcttt cgcaatggga attgtcgata ccacgccgat tattaatgct
      661 cactggtttg cgctgccgac cctctatacg ccgcgcttcg agtggtttgc cattctgact
      721 attctgccag cggcgttagt ggttattgcc gaacacgtag ggcacctggt agtaacggct
      781 aatatcgtca aaaaagatct gctgcgcgat ccaggtctgc accgttcgat gtttgctaac
      841 ggcttgtcga ccgtgatctc cggcttcttt ggctccacgc caaacaccac ttacggagaa
      901 aacattggcg tgatggcgat cacccgtgtt tacagtacct gggttatcgg cggtgcggcg
      961 attttcgcta tcctgctttc ctgcgtcggt aaactggctg ctgctatcca gatgattcca
     1021 ttgccggtga tgggcggcgt ttcgctgctg ctttacggtg tcatcggtgc ttccggtatt
     1081 cgtgtgttga tcgaatcgaa agtggattac aacaaagcac agaacctgat cctgacttcc
     1141 gtgattttga tcatcggcgt cagtggcgcg aaggtaaaca ttggggcggc ggagctgaaa
     1201 ggtatggcgc tggcgaccat cgtcggtatc ggcttaagtt tgatcttcaa actgattagt
     1261 atgctgcgcc ctgaagaagt ggtgctggac gcagaagacg cggatataac agacaaataa
     1321 tgtaccgacc gggcagtgtt gctgcccggt tcaaacatca tgggattctg tggtaaactt
     1381 ctcgcgattt tgtgaaatcc tggttgaggt atctctgaac acaccggcac agctctcttt
     1441 gccactttat cttcctgacg acgaaacctt tgcaagtttc tggccggggg ataactcctc
     1501 tttactggcc gcgctgcaaa acgtgctgcg tcaggaacat agcggttaca tctatctctg
     1561 ggcacgcgaa ggcgcggggc gcagccatct gctgcacgcg gcttgcgcgg aattgtcgca
     1621 gcgtggcgat gcggtgggct atgtcccgct ggataaacgc acctggtttg ttccggaagt
     1681 gctcgacggt atggagcatt tgtcgctggt ctgtattgac aacattgagt gtattgccgg
     1741 cgatgagttg tgggagatgg cgattttcga tctctacaat cgaattctgg aatcgggcaa
     1801 aacacggttg ttgatcaccg gcgatcgtcc accgcggcag ttgaatctgg gattaccgga
     1861 tctcgcgtcg cgtctcgact gggggcagat ctacaaattg cagccacttt ctgatgaaga
     1921 taagttgcag gcgctacagt tacgcgcgcg tttgcgtggt tttgaactgc cggaagatgt
     1981 ggggcgtttc ttgctgaagc ggctcgacag agaaatgcgc acgttgttta tgacgctgga
     2041 tcagctggat cgtgcgtcga ttaccgcgca acgcaagctg accattcctt ttgtgaaaga
     2101 aattctgaag ttgtagataa ggtgtttatt gtcggatgcg gcgcgaacgc cttatccgac
     2161 ctacgcgaag ttaatccata gtattcgtag gccggataag acgcggcaag cgtcgcatcc
     2221 ggcaatgtgc ttcaactagc gatggagcac atcttaaccc acgatttcca gtacctgctc
     2281 cggtggacga ccaatccgtg ctttgccatt cgcgaccaca atcgggcgtt ccattagttt
     2341 cggattatcc accatcgcct gaatcagcgc ctcttcgcta agtgaactgt cagccaggtt
     2401 cagttcttta taaagatcct ctttttggcg catcaattca cgagcgctat tcatccccag
     2461 cattttcagc aaatcacgca gcgttgccgc atcggcgggt gtctcaaggt agagcaccac
     2521 ttctggctcc acgccgtttt ctttcagcag gttcagcgtt tcccggctct ttgaacagcg
     2581 tgggttatgg tagattttta cctgtttggt cattgttctt cctttaatgc gaattacatc
     2641 ttggtataag gcttaaagcg ttcctgcagc tggcgcaact ggtcgatgcg cgcatcgtaa
     2701 cgcgcttgtt gcaggctgcc taatttcacc tgcgaactgg cgctactcaa caaggaaata
     2761 gcctgatcga gtcgcccggc gagcgcataa ccttctgctc gcgcagccag ttcctgatcg
     2821 cggttattta gtgcggcttc cgcctgtgcc agtaaatccc agccgttgct gtcatcttta
     2881 ttgttaaaag tgtagcgatt cagaatattg gccgcttcct gtggttgccc cccttgcaga
     2941 taagcgttcg ccaggttgag ctgcaacacc ggattggtgc gcaaatcgcg ggcatttttc
     3001 aggcgattga tagcgtcatt ggctttgttt tgcccaagat cgatatcggt agccagatcg
     3061 agataccatg cgttgccagg ttctgctgcc agtaacggtt gcagcgtttt acgcgcttcg
     3121 tcgtatttat tggcttccat cgcctgtaga gcacgaccat attgcgccgc tcgttgctga
     3181 cgaacgtttc ctttcgccca ttcatccagc aaatcactgg tgagctggtt acgtccggaa
     3241 ttatacatcc ccagtgtgcg cgctttcgcc agatagaaat cttccgacga ctgcaccacc
     3301 atcgggcgca tctgattagc acggttgcgg gcatctgcca gacgactttc cggcaacggg
     3361 tgagtcaata aaatttccgg cggacgcgag gagtaacgcg cctgatcgag taatttttcg
     3421 aggaaggtcg gcatcgcctg cggatcgaat cccgagcgtt gcagcacctg aataccaatg
     3481 cggtccgctt cctgttcatt ttgctgggtg aaactgatca tcccctggcg cgttcccgcc
     3541 agtgtaccgg tcagcgccgc catccccgcc tgcggactgg ccatcgccag taaaatagaa
     3601 cctaacgcgc cgacccaggt cagcggcgcg ctgcgctgct gatcttccat cgctcgcgcc
     3661 aggtgacgtt gggtgacgtg ggagatttcg tgcgccataa ctgaagccag ttgactttcg
     3721 ttatcggaat aacggaacag ggcagagtgc agcaccacgt tgccgccaaa gaaagcaaag
     3781 gcgttaattt cgtcgttgtt gatcagaaag aaatgaaacg gtgtcttaac cgaattggca
     3841 tgcgaaacca gacgcattcc tagcgaatta atatattgcg ttaatagcgg gtcattaatt
     3901 aacggcgcgc tgccgcgtaa ctggcggaca taatagtcgc ccatctgcat ttcctgacca
     3961 atggaaagtg tgcttcctgc ggaggttccc atatccggca aggtgtctgc gctgtcggca
     4021 aacgccgggg ctacctgacc aatggtcata gcagcaatga gggttgcaac caggtttttt
     4081 ttcaactgcc tgaacataac ctctatcctg tatttctgga gatagtcatt tgaccgatac
     4141 tgtgaaatat cgttcccacc gcgccgcctt tgagtgtaac gacgaagatt agcccactca
     4201 aataactttt cagtttcctg aatccgtcat aaaaagcgaa gtcttttttg tgacatttcg
     4261 atacaattgc ggatcgcaat cccgctcttg aggttcaggt aaggtctgta tgctcgaaat
     4321 gttgatgcaa tggtatcgcc gccgttttag cgacccggaa gcgattgcct tgctggttat
     4381 tttagtcgcc ggatttggca ttatcttttt ctttagtggc ctgcttgctc cgttgctggt
     4441 ggctattgtg ctggcctatt tgctggagtg gccaaccgtg cgcctgcaat ctattggctg
     4501 ttcccgccgc tgggcgacgt cgattgtatt ggtggttttc gtcggtatat tgctactgat
     4561 ggcgttcgtg gttctgccta ttgcctggca gcagggcatc tacttaatcc gcgatatgcc
     4621 ggggatgctc aataagcttt ctgactttgc cgccacgttg ccgcgccgct atccggcgtt
     4681 aatggatgcg ggcattattg atgcaatggc cgaaaatatg cgcagtcgga tgctgaccat
     4741 gggcgattcg gtggtgaaaa tttccctcgc ctcgttggtc ggtttgctga ccattgccgt
     4801 ctatctggtg ctggtgccat tgatggtctt cttcctgctg aaagacaaag agcagatgct
     4861 gaacgccgtt cgccgggtgc tgccgcgcaa ccgtggactg gcaggacagg tgtggaagga
     4921 gatgaatcaa caaatcacca actatatccg cggcaaagtg ctggagatga tcgtggtagg
     4981 gatcgccacc tggctggggt tcttgctctt tgggctgaac tattcgctgc tgctggcggt
     5041 gctggtcggc ttctcggtac ttattccgta cattggcgca tttgtggtga ccattccggt
     5101 ggttggcgtg gcgctattcc agtttggtgc tggcacggaa ttctggagct gcttcgcggt
     5161 gtatctgatt attcaggcgc tggacggcaa cctgttagta ccggtgttgt tctccgaagc
     5221 ggttaacctg catcctctgg tgattatttt atcggtggtg atcttcggtg gtttgtgggg
     5281 attctggggc gtattcttcg ctattccatt ggcgacgctg atcaaagccg tgattcacgc
     5341 ctggcctgat gggcaaatcg cgcaagactg accttcagcg aaaaatttga aacgagtgtt
     5401 gcagggcagt gagaagattt gagatgtgct ggccgcaagc gcagccagca cggaatggag
     5461 caaagtaatc aggcgtgttc tttcagccag ttcagcacaa cgtcgtggtg attgctggtt
     5521 ttgaaatcgt caaagacatg ttcgattttg ccatcagcgt caatcaggaa gctgatgcga
     5581 tgaataccat cgtaggtttt gcccatgaag gacttttcac cccagacgcc gaattgttcg
     5641 cacacctggt ggtcctcatc agacaggagc gtaaagttaa gcagctcttt ttccgcaaaa
     5701 cgggagagtt tttcgggttt atcggtgctg atacccagca catcaacgcc cgcttttttc
     5761 aactcatcca tgttatcgcg taagccgcag gcctgtacgg tacagccggg ggtcatggct
     5821 ttcgggtaga aataaaccag aacacgctgt ccctggaagt cggtcaaatt aacttgttct
     5881 ccgtcttgat ccggcaagct aaatttcggt gcgatatcac cggctttcag tggattcatt
     5941 acttaactcc atcctgttca tcatgttggg aataattgac gacgttaata ctgccttgtg
     6001 cattgagttc tgtacatagg gctttgaacg cttgctcaat atttgctgcg tccgcagatg
     6061 cggggctgtg ggcagttatc tgaatatgta actgcgcagc ccgttcattt tcagcaggtt
     6121 gcgtgcgcga caccagctcc gcaatgttca tatgatgcgc gtcgaaaagt gctgtgaagc
     6181 gttcaattaa atgcggggag tctgccacat cgacctgaac ccagacagat gctggcattg
     6241 gtggacgcgg acgcgccgtc gtgcgcttca tcacgattaa aagatccagt tcggcacctt
     6301 tcaacggtaa cgttgattca atcagggtga ttgcattcca tgaaccggaa agcagcatga
     6361 taaacgtgaa ctcttctccc agcatcgcca ggcgactgtc ttcaatatta cagccgcaac
     6421 tactgacatg acgggtgatg gtgttcacta ttccagggcg atcggcaccc aacgcagtga
     6481 tcaccagata atgttgcgat gacagtgtca aactggttat tccttcaagg ggtgagttgt
     6541 tcttaaggaa agcataaaaa aaacatgcat acaacaatca gaacggttct gtctgcttgc
     6601 ttttaatgcc ataccaaacg taccattgag acacttgttt gcacagagga tggcccatgt
     6661 tcacgggaag tattgtcgcg attgttactc cgatggatga aaaaggtaat gtctgtcggg
     6721 ctagcttgaa aaaactgatt gattatcatg tcgccagcgg tacttcggcg atcgtttctg
     6781 ttggcaccac tggcgagtcc gctaccttaa atcatgacga acatgctgat gtggtgatga
     6841 tgacgctgga gctggctgac gggcgcattc cggtgattgc cgggaccggt gctaacgcta
     6901 ctgcggaagc cattagcctg acgcagcgct tcaatgacag cggtatcgtc ggctgcctga
     6961 cggtaacccc ttactacaat cgtccgtcgc aagaaggttt gtatcagcat ttcaaagcca
     7021 tcgctgaaca tactgacctg ccgcaaattc tgtataatgt gccgtcccgt actggctgcg
     7081 atctgctccc ggaaacggtg ggccgtctgg cgaaagtaaa aaatattatc ggaatcaaag
     7141 aggcaacagg gaacttaacg cgtgtaaacc agatcaaaga gctggtttca gatgattttg
     7201 ttctgctgag cggcgatgat gcgagcgcgc tggacttcat gcaattaggc ggtcatgggg
     7261 ttatttccgt tacggctaac gtcgcagcgc gtgatatggc ccagatgtgc aaactggcag
     7321 cagaagggca ttttgccgag gcacgcgtta ttaatcagcg tctgatgcca ttacacaaca
     7381 aactatttgt cgaacccaat ccaatcccgg tgaaatgggc atgtaaggaa ctgggtcttg
     7441 tggcgaccga tacgctgcgc ctgccaatga caccaatcac cgacagtggt cgtgagacgg
     7501 tcagagcggc gcttaagcat gccggtttgc tgtaaagttt agggagattt gatggcttac
     7561 tctgttcaaa agtcgcgcct ggcaaaggtt gcgggtgttt cgcttgtttt attactcgct
     7621 gcctgtagtt ctgactcacg ctataagcgt caggtcagtg gtgatgaagc ctacctggaa
     7681 gcggcaccgc ttgcggagct tcatgccccg gctggaatga ttttgccggt gacctccggc
     7741 gattatgcaa tcccggtgac caacggtagt ggtgctgtcg gtaaggcgct ggacattcgt
     7801 ccaccagccc agccgttggc actggtttct ggcgcgcgta cccagttcac gggcgatacc
     7861 gcttcattgc tggtggaaaa tggtcgtggc aatactctgt ggccgcaggt ggttagcgtg
     7921 ctgcaggcga aaaactacac catcacccaa cgtgatgatg ctggtcagac actgaccacc
     7981 gattgggtac aatggaaccg tctggacgaa gacgagcagt atcgtggtcg ttatcaaatc
     8041 tctgttaagc cgcagggtta tcagcaggcg gttacggtta aactgctgaa cctggaacag
     8101 gcgggcaaac cggttgcaga cgcggcgtcc atgcagcgtt acagcacgga gatgatgaac
     8161 gttatttccg ccggtctgga taaatctgcc actgacgccg cgaacgctgc gcaaaatcgt
     8221 gcctccacca ctatggacgt acaaagtgca gctgatgaca ccggtttacc aatgctggtc
     8281 gtacgcgggc cgttcaatgt ggtttggcaa cgtctgccag ctgcgctgga aaaagtgggc
     8341 atgaaagtga ccgacagcac ccgttcgcag ggcaacatgg ccgtaactta taagccgctg
     8401 tctgacagcg aatggcacga actgggcgcg agcgatccag gtctggcatc cggtgactat
     8461 aaactgcagg ttggcgattt agataaccgc agcagcctac agttcatcga tccgaaaggt
     8521 catactctga ctcagagtca gaacgacgcg ctggtagctg tcttccaggc tgcgtttagc
     8581 aagtaaaaat acagggctgg agtcatccgg cccttttttc tgatatgata cgcaaacgtg
     8641 tgcgtcggca gaaaaacgcg attttagcgg taattcgcac gaaatttgtt tgtcggacgt
     8701 aggtcggata aggcgttcac gccgcatccg acaaaacatc cggcacacca gacagcaaaa
     8761 gattttaaaa cgttaattca cacccaggag tgataaagat gcaaaagcaa gctgagttgt
     8821 atcgtggtaa agcgaaaacc gtatacagca cggaaaaccc ggacctgttg gtgctcgaat
     8881 tccgcaatga tacgtcagca ggggatggcg cgcgcattga gcagtttgat cgcaaaggta
     8941 tggtgaacaa caagttcaac tacttcatta tgagcaaact ggctgaagcg ggtatcccga
     9001 ctcaaatgga gcgtctgctc tccgataccg aatgtctggt gaaaaagctg gatatggtgc
     9061 cggttgagtg tgtcgtgcgt aaccgtgctg ctggctctct ggtgaaacgt cttggaatcg
     9121 aagaaggtat tgagctgaac ccgccgctgt tcgatctgtt cctgaaaaac gacgccatgc
     9181 acgatccgat ggtcaacgaa tcttactgcg aaacctttgg ctgggtgagc aaagagaacc
     9241 tggcgcgtat gaaagagctg acctacaaag cgaacgacgt gctgaaaaaa ctgttcgatg
     9301 atgctggtct gattctggtc gacttcaagc tggagtttgg tctgtacaaa ggcgaagtgg
     9361 ttctgggcga tgagttctcc ccggacggca gccgcctgtg ggacaaagaa acgctggaga
     9421 aaatggacaa agaccgtttc cgccagagcc tcggtggcct gatcgaagcc tatgaagccg
     9481 tcgcccgccg cctgggtgta cagctggact gatttttctg ttcatcatct tgccgtgctg
     9541 ctggcacggc aagacaaccg ctctcataag atgagtattg aacgctcatt cctccgccat
     9601 ttcatcccgc tttcctgtgg taatcttcct ctgaaccacc tacgatcatt tctataatga
     9661 atataatgtt gaggtatcta tgcgttggca agggcgacgt gaaagtgaca atgttgaaga
     9721 caggcgcaat agctccggcg gtccgtcaat gggcggtccc ggttttcgcc tgccaagcgg
     9781 taaaggcggg ctgattttac tgatagtcgt gctggttgca ggctactatg gcgttgattt
     9841 aaccgggttg atgaccggac agccggtttc ccaacagcaa tcaacgcggt caattagccc
     9901 taatgaagac gaagccgcaa aattcacctc ggtgattctg gcaaccacgg aagacacctg
     9961 gggacagcaa ttcgagaaga tgggtaaaac ctatcagcaa ccgaagctgg tcatgtaccg
    10021 tggaatgacg cgtaccggct gcggggcggg ccagtccata atggggccat tctattgccc
    10081 ggcggatggc acagtttata tcgatctctc cttctatgat gacatgaaag acaaacttgg
    10141 cgcggatggc gattttgccc aggggtacgt tatcgctcat gaagtcggtc atcatgtgca
    10201 gaaactgtta ggcatcgagc cgaaagttcg tcaactgcaa caaaacgcga cgcaggcgga
    10261 agtaaaccgc ttatctgtgc gtatggaact ccaggccgac tgttttgccg gtgtctgggg
    10321 gcatagtatg cagcagcaag gtgttctgga aaccggcgat ctggaagagg cgctgaacgc
    10381 ggcgcaggcc atcggcgatg accgtttaca acagcaaagt caggggcgag tagtaccaga
    10441 cagtttcact catggcactt ctcagcaacg ctacagctgg tttaaacgtg gtttcgacag
    10501 cggcgatccg gcacaatgca atacttttgg taaaagcatt taacttccgg ggcagggatg
    10561 gctgaactga ctgcgcttca cacattaaca gcgcaaatga aacgtgaagg gatccgccgc
    10621 ttgctggtgt tgagcgggga agagcgttgg tgttttgatc atgcgcttaa gttgcgtgat
    10681 gccttacctg gcgactggct gtggatttcg ccgcagccag atgctgaaaa ccactgttct
    10741 ccctcggcac tacaaacttt acttgggcgc gagttccggc atgcggtatt cgacgcccgc
    10801 cacggctttg atgccgctgc ctttgcggca cttagcggaa cgttgaaagc gggaagctgg
    10861 ctggtgttgt tactccctgt atgggatgag tgggaaaacc aacctgatgc cgactcgctg
    10921 cgctggagtg attgccctga ccctattgcg acgccgcatt ttgtccagca tttcaaacgc
    10981 gtacttacgg cgaataacga cgctatcctc tggcggcaaa accagccgtt ctcgttggcg
    11041 cattttactc cccgtactga ctggcacccc gctaccggcg caccacaacc agaacaacag
    11101 caactcttac agcagctact gaccatgccg ccgggtgtgg cagcggtaac tgctgcgcgt
    11161 gggcgcggta agtcggcgtt ggcagggcaa ctcatttctc gtattgcggg cagtgcgatt
    11221 gtcaccgctc ccgcaaaagc ggcaacggat gtactggcac aatttgcggg cgagaagttt
    11281 cgctttattg cgccggatgc cttgttagcc agcgatgagc aagccgactg gctggtggtc
    11341 gatgaagccg cagctatacc tgcgccgttg ttgtatcaac tggtatcgcg ttttcctcga
    11401 acgttgttaa ctactacggt gcagggctac gaaggcaccg gacgtggttt tttgctgaaa
    11461 ttttgcgctc gctttccgca tttacaccgt tttgaactac aacagccgat ccgttgggcg
    11521 cagggatgcc cgctggaaaa aatggttagt gaggcactgg tgtttgacga tgaaaacttc
    11581 acccatacac cacaaggcaa tatcgttatt tccgcatttg aacagacgtt atggcgaagc
    11641 gagccagaaa cgccgttaaa ggtttatcag ttattgtctg gtgcgcacta ccggacctcg
    11701 ccgctggatt tacgccgcat gatggatgca ccaggtcaac attttttaca ggcggctggc
    11761 ggaaacgaga ttgccggagc gctgtggctg gtggatgagg gcggattatc tcaagaactc
    11821 agtcaggcgg tatgggcggg ttttcgtcgc ccgcggggta atctggtggc ccagtcgctg
    11881 gcggcgcacg gcagcaatcc actggcggcg acattgcgcg gacggcgggt tagccggata
    11941 gcagttcatc cgactcgtca gcgggaaggc acagggcgac agcttattgc tggtgctttg
    12001 caatatattc atgacctcga ctatctttcg gtgagttttg gttacaccga ggagttatgg
    12061 cgtttctggc aacgctgcgg ttttgtgctg gtgcgaatgg gtaatcatcg tgaagccagc
    12121 agcggttgct atacggcgat ggcgctgtta ccgatgagtg atgcgggtaa acagctggct
    12181 gaacgtgagc attaccgttt acgtcgcgat gcgcaagctc tcgcgcagtg gaatggcgaa
    12241 atgcttcctg ttgatccact aaacgatgcc gtcctttctg acgacgactg gcttgaactg
    12301 gccggttttg ctttcactca tcgtccgcta ttaacgtcgt taggttgctt attgcgtctg
    12361 ctacaaacca gcgaactggc attaccggcg ctgcgtgggc gtttacagaa aaacgccagt
    12421 gacgcgcagt tatgtaccac acttaaactt tcaggccgta agctgttact ggttcgccag
    12481 cgggaagagg ccgcgcaggc gctattcgca cttgatgatg ttcgcactga gcgtctgcgc
    12541 gatcgcataa cgcaatggca attttttcac tgactccttc aattttctcc catggtcatt
    12601 gtgagtcagc ggcgtaaaat taatgacatc agttaaggag ttcgccatga aacatgacca
    12661 ttttgttgtt caaagcccgg ataaaccagc acaacagttg ttactgcttt tccacggtgt
    12721 cggggataac ccggtggcaa tgggggaaat aggtagctgg tttgcgccgc tgtttcctga
    12781 tgcgctggtg gtgagtgtcg gtggcgcgga gccgagcggt aatccggcgg ggcgtcagtg
    12841 gttttcggtg cagggtatta cggaagataa tcgccaggcg cgtgtgaatg ccatcatgcc
    12901 gacgtttatt gagacggtgc gctactggca gaaacaaagc ggagtagggg ctaacgccac
    12961 ggcgctaatc ggtttctcac aaggcgcgat tatggcgctg gagagcatta aagccgaacc
    13021 gggccttgct tcgcgcgtca ttgccttcaa cggacgctac gcgagcctgc cggaaaccgc
    13081 gtctacagcc acaacaattc acttgattca tggcggtgaa gatccggtta tcgatctggc
    13141 gcatgcggtt gcggcgcagg aagcgttaat cagtgccggt ggtgacgtga cgctggatat
    13201 cgtggaggat ttaggccatg cgatcgacaa tcgcagtatg caatttgccc tggatcactt
    13261 gcgttatacc attccgaaac attatttcga cgaagcgcta agcggcggta agcctggcga
    13321 tgatgatgtg attgaaatga tgtaataata gccgggtagg tctgataaga ctgtatcagg
    13381 catcatggcc ggatgcggcg ttaacgcctt atccggccac ttagcttact tcttcggttg
    13441 atcctttttc ggccagtcgt cgtcatcgtc ccacttatcg ttgaaatcac gatgcggggg
    13501 aagctccggc ttgttggcga gaaatttctt atggtcgacg cgcttgagat ctttaatcac
    13561 gttcagcagg acgcctacca aaaagacaat caccagaatc caccaatatt tagccagcca
    13621 gtccatgctt atttcctctt gcagaaccac tcatcaggcg acgagctgtt ccatgatacg
    13681 ttgatacata cgggcaagta gctgcaggtc ggcagcgttc acacattcat tgattttatg
    13741 aatcgtggca ttgaccggcc cgagttccac cacctgcgcc cccatgcggg caataaagcg
    13801 cccgtcggac gttccgcctg tggtcagtag ctgcggttta atttcattat agtgctcaac
    13861 cgcgttaacg accgcatcca ccagtttacc gcgcgcggtc aaaaatggct gcccggaaag
    13921 ccaccaatcc accgtatagc gcagttgatg tttttcaagc agggcaagca cctgcgcttt
    13981 gatcatctca tccgtcagtt cggtgctaaa gcggaagtta aactgcacaa acagttcacc
    14041 tggaataacg ttgttactgc ccgttcccgc ctgaatattg gcaatctgca tactggtcgc
    14101 cgggaagaag tcattaccct gatcccactc aatagccact aattcattaa tgaaaggtgc
    14161 tgcgcgatgt accggattgt cagccagatg tgggtaggca acatgcccct gaacgccatg
    14221 aatggtaagg ttgcaggtta acgatccgcg acgaccattt ttcaccacat cacctaccac
    14281 ttcgatactc gacggttcgc caaccagaca gtaatcgaga cgctcattac gcgccattaa
    14341 cgcttcgacg acttttaccg taccgttgtg ggcactagct tcttcatcag aggtgatcag
    14401 aaatgccagt cgccctgtat ggttgggatg ttgtgcgaca aagcgttctg ccgctaccac
    14461 catcgccgcc agcgagcctt tcatatctgc cgcacctcgc ccaaataaca tgccgtcacg
    14521 aatggttggt tcaaatggtg gattgatcca acggtcggcg tcgccaggcg gcaccacgtc
    14581 ggtatgcccg gcaaaggcta acgtttcacc ctgcccgcgc catgcccaaa aattctgcgt
    14641 atcggcaaag tccatgcgtt caacggtaaa accgatcgcc tgcaaacgtt caatcaacaa
    14701 agcctggcat cctgcgtcat caggactcag ggaagggcgg cgaataagct gttgtgtcag
    14761 ctcaataacc gggcacgaca tagactacac ctcatggaaa aattgctgat aactggattc
    14821 actgaaaccc agcagcatag gcttaccagg cgcgcagagc aatggacgtt tgataattgc
    14881 aggcatttca gtcattaatg tcgccgcaga ggccgcatcg gtgattttat tgcgggtggt
    14941 ttcgtccagt ttacgccagg ttgtaccacg ggtgttgagt aacgcttccc agcctaattc
    15001 gttgataaaa ccgttcaata attcgctgtc caatccatcg acgcggtaat catgaaaacg
    15061 atagtcgatg ttattggctt ccagccaacg gcgagccttt ttaatggtgt cacaattttt
    15121 gatgccgtaa agtgtaacca taatgaatcc tttttcgatt tatgagaata aatactcatt
    15181 taagggtgaa aacattttgc ctgcaaatga ttatcaggaa atataacatt atcgaagtat
    15241 tcaaattaac aactattaaa taacattaaa catttttaac gtaaacatta agaatattca
    15301 tcttgttatc tgtctgtatt ttaaccagaa ttaaatcagt attagatgcc gtatgaatat
    15361 ctcgaaatgt tgcggtgtat cacatacaaa tcatcaccgc aggaccatag tatttacata
    15421 aggtttgtcc cccggaggta gtcatcgcag caatcgagta aattagcttc accacggtat
    15481 attgtttccg tagaataccc ataattataa gagaggttgt tatgattgaa cgtgaactgg
    15541 ggaactggaa agactttatc gaagttatgc ttcgtaagta attcctgaga caaagtacaa
    15601 acagcaagaa cccgctgagc aggttcttaa tcggaaagtt gaaaagggcg acacattggc
    15661 atgtcgcctt ttttattgct tattccgggc gcggcttcag cgggaagcgg cggcgcacca
    15721 gcacaaagaa cagcggcacg aagtaaatag ccagaatagt ggccgaaatc atcccgccca
    15781 ttacgccagt acccaccgca tgctgaccac cggaaccggc acctgtgctg gttgccattg
    15841 gcaatacgcc gaagataaat gccagcgagg tcatcagaat cgggcgtaaa cgctgacggc
    15901 aggcgtggag cgtcgcttca aacaggtcgt ggcctttttg gttcatctcg ttagcaaact
    15961 cgacgatcag gatggcgttt ttcgccgata aaccaatgac cgttaacagg cccacctgga
    16021 agtaaacatc gttttccagc ccgcgcatcc aggttgccag cagcgcgccg ataaccccca
    16081 gcggcacgac cagcattacc gagaacggca ccgaccagct ttcatacagc gcagccagac
    16141 acaggaatac caccagcaag gaaatggcgt acagcgccgg agcctgcgcg ccggaaagcc
    16201 gctcctgata cgacatcgcc gtccactcca gaccaaagcc gtttggcaac tgcttcacta
    16261 acgattccat aatatccatc gccgtaccgg tactgacccc cggtgcggct tccccaacaa
    16321 tctcaaccgc agaataaccg ttatagcgtt ccagacgcgg cgagcctgtc tcccagcgtg
    16381 aggtcgcgaa agcagagaag ggcaccatgc cgccatcttt atttcggaca taccagagat
    16441 tgatgtcatc tggcagcatg cgatacggcg cagctgcctg cacatagact ttcttcacgc
    16501 gaccgcgatc cataaagtca ttcacatagc tcgaacccca ggcggtttgc agtgtgtcgt
    16561 taatatcgtc gatagcaacg cccagcgcct gagctttacg ctggtcgata tcaatctgca
    16621 actgcggact gtcgtcgagg ccgttatggc gcacacgggt tagctccggg ttttccgctg
    16681 ccagcgccag caactggttt cgtgctgcca tcagcgcatc gtgacccgct ccagcgtggt
    16741 cctgcaactc catatcaaaa cccgcagaac taccaagacc gctaattgct ggcgggctgc
    16801 tggcgataac gcgagcttct ttaatcttgt taaacgcctt cgttgcacgc tcgataatgg
    16861 caaacgaggt gccggtctta ctgtcgcgtt cgctccagtc tttcaggcgg ataaacattc
    16921 gcgccacgtt ttgcccgttc cccccagggc cagaacccac ggtggcaaac accgacatga
    16981 tgttgtcttt ttcatgggtg aagtaatatt tctcgatttg ctcaacgact ttcagggtct
    17041 gttgctgggt tgaaccgctg ggcaactgta ccgaggtagt aaacatgcca cggtcttcca
    17101 gcggtaagaa cgacgtcggc aaacgcagga acaggaacac catgccgcca agcagcagga
    17161 cataaatcac aatccagcgc aggctacggt ggagaatttt cgccacccct ttttcgtagc
    17221 gttcggcgtt gcggttaaac atctggttaa accaggcaaa aaagcctttt tgcccgtgat
    17281 gctcaccttt tttcagtggc ttaagtagtg tggcacacag agccggagtg aggatcatcg
    17341 ctaccagtac tgacagcacc atcgccgcaa caatggtaat agagaactgg cgatagatgg
    17401 caccggtggt gccgccgaag aaggccattg gcacaaatac cgccgaaagc accatcgcaa
    17461 tcccgaccag tgccccctgg atctgcccca tcgatttacg tgtggcttcg cgaggagtga
    17521 gtccttcctc actcataata cgttcgacgt tttccaccac cacgatggca tcatccacca
    17581 gcagaccgat cgccagcacc atcgcgaaca tggttaaggt gttgacgcta tagccgaagg
    17641 cataaagcac cgagaaggtt cccatcaaca ccaccggcac ggcgatagtg ggtatcagcg
    17701 tggcgcggaa gttttgcagg aacagataca taacgaggaa aaccagggcg atagcttcca
    17761 gaagcgtttt caccacgtct tcaatggagg cttttacaaa agaggtggtt tcatacgcca
    17821 ccttgtattc cagtccgtgt ggaaaatact gcgccagctc gtcgagacga ttgagcacca
    17881 gctccgctgt cgccatttcg ttcgcgccgg aggccagttt tacccccagc ccggaggctg
    17941 gcttaccatt gaagcggcta agataatcgt atttctccgc ccccatttcg acggtggcga
    18001 catcgcccag ccttacctct gagccgtcct gattcacccg caaggtgata tcgcggaact
    18061 gttctggtgt ttgcagcagt gactgggcgt taatggtggc gttgagcgcc tgcttatcga
    18121 cggaaggcgt accaccaagt tgcccaaccg caatctgcgc gttctgtgat tcaatggcat
    18181 cggtgacatc tttagccgtc atctggaaac tgttgagttt cgccgggtcc agccagatac
    18241 gcatggaata ttgcgaacca taggcatcga tatccccgac gccattcacg cggcttaacg
    18301 ggtcctgaat attactggca acataatcgg caatatcctg tttatccatc gaaccatcgg
    18361 tagagacgaa ggcaatggtc agaatgttgg tatcgccggt tttacgcacc gtcacgccct
    18421 gattttgcac cgcctgcggt aactttcgca tggctgattg cagctggttt tgtacttgct
    18481 gcacggcttc gtccggatcg gtgcctgctt taaaacttaa cgtgacagat gcctgaccgg
    18541 tgccgctgct ctgagatgac atatacatca gattatcgag gccggtcata ttttgctcga
    18601 taacctgggt cacggtgttt tccagcgtct gggccgatgc gccgggatag ttagcggtca
    18661 ctcgcacatt cggtggcgcg agatcggggt attgttcaac gggcaatgaa aaaatcgcca
    18721 gggtacctgt cagacacaac aggattgcca gcacccaggc aaaaatgggg cgatcaataa
    18781 agaaattcgc cattaaaaga ggacctcgtg tttctgcgta tcgttgtagg cttggcttgc
    18841 ttcactgtag cggcaaggta cgagccaatc gtggagaaaa aaaggagtta atgtaaatta
    18901 tcatgccctt ttatactgaa ccttaagtgc cactattctt tggtcaataa gaggcattac
    18961 atcagctgac tttcctcacc ctccgcagag cgaaagctaa tactcactaa cgtgccgccg
    19021 ccggaaggtt gtgaaaaagt cagcgtccca cccaatcttt ccgcgcgttc gcgcatgata
    19081 ttcagaccat aatggccttc gggttctttc ggttcaccga tgccaatccc gttgtcgcga
    19141 atatagactg tgtgattgcc atccggcgcg gtgacgcagc taacggcgat ttcgctggcg
    19201 ttggcgtgct tcatcgcatt cagcaccgct tcgcgaataa tttgcaacaa atgcacctgc
    19261 atttgcgcat ccagcgccag ggttggcaga cggcagtcga gggtcagttt ggcgctggtt
    19321 tgattttgta acgtatccag catttccctc aacgcggagg ggagatccgc ctgctgcagc
    19381 gtcaggcgga aagtagtcaa cagctcgcgt aactgccgat aagcatcatt caacgcctgg
    19441 gaaaaatcgg ccatgatact ttgtgcggtg gcgttatctt ccggtatcga acgcttcagt
    19501 aacgtcaact ggatacgtaa gtaagaaagt acctgagcca gcgagtcgtg caattcgcgg
    19561 gcgatggtcg cacgttcttc catcaacaat aactgctgaa aatgcttctg cgcctgatta
    19621 aagtacaaac cgcgtcccag catcgacgaa acgctgttaa gcagcggttc tgatgatgaa
    19681 acgtgactat tttgccagtg cagttctccg taaaccgtct cttgcattgt caccggtaaa
    19741 atctgcatcg gcaattccgg gtttggctgc ccttcgctaa tccgccagtt gtcaccgaca
    19801 tttaactcca gatattcagc cgcttcattg tcgcgaacaa tctgcaaaat atggcggaaa
    19861 caatgcacat caatctggct ggtgtttagc gcctgcgaac actgatacaa cacctccaga
    19921 cgacgcttgg cctcgtggag atcgcgggtc ttttcttcta ctgacgcctc cagcgaacgg
    19981 tacaatttat gcagctcgct cgacatctgg ttaaaggttt ttgcaagcag gccaagctca
    20041 ttcggcaggc tggtatccag cggcggcgag tcgaactgcc cgtgttcaat acgctgactg
    20101 gcggtaacca gctgattcag cggggcaacc acctgatggc gtatgcggcg caaagtaaaa
    20161 aagaccagcg tgaaaatacc gatgccgcca gccagggaaa ttgccaccac cagcagcatt
    20221 ttgcgttcag cgtagtgctg taaagccagc acgaacaggt ctatctgatt aacataatta
    20281 ttaatattgg cctgatacca cggcaagtcg cccttgctga gccgattatt catctccagc
    20341 cagttggcat tcagatgcgc atagcgggtt tttactgcct ctggcacata ccagacgttg
    20401 agattggtta ataccggtga atgcagtgcc tgctgaaata actggcgatg tgcattgagt
    20461 tgtggactgc cactttgcaa gtcgtagccc aggcggtaac tctgcatacg cagcgatccg
    20521 gcaatattga tagcctcagc gtcgcgtaaa ctgctcgcca gcgttagcag agcgataccc
    20581 gtggaaagaa tcgacagcag cacaatgtaa aaaaaggccc gggccagact ggccgagacg
    20641 ggtcgtttaa caatcacacg cgtcttctcc acaaaaaatc attaatcttc cagttcgctg
    20701 aaacgcaatt tagtcagtga tgggattatt tgatctgcca cagtttatag cgaaatagtt
    20761 acttattctg ggcacatgaa cattgccgat tcccctgtaa gtcgggtaat aacaacactc
    20821 atataaagaa taaggttttt acaaccaaaa aagaaggtcg ttatgaatcg ttttattatg
    20881 gccaacagtc agcaatgtct gggttgtcat gcttgtgaaa tcgcctgtgt catggctcac
    20941 aatgacgagc aacatgtcct gagccaacac cattttcatc cccgaattac ggttatcaaa
    21001 catcagcagc aacgtagtgc cgtgacctgt caccattgtg aagatgcgcc ctgcgcccgt
    21061 agctgcccta atggcgcaat cagccacgtt gatgacagca ttcaggtcaa tcagcaaaag
    21121 tgtattggct gtaaatcctg cgtggtggcc tgtccatttg gtacgatgca aatcgttctg
    21181 acacccgttg cggcaggaaa agtaaaagcc acggcgcata aatgcgacct ttgtgcaggg
    21241 cgcgaaaacg gtcctgcctg tgtcgaaaat tgcccggcgg acgcgctgca actggtcact
    21301 gacgccgcac tctccggcat ggcgaaatcc cgccgcttgc gcaccgcacg tcaggaacat
    21361 caaccgtggc atgccagtac cgcggcgcaa gaaatgccgg taatgagtaa agtcgagcaa
    21421 atgcaggcaa cgcccgcgcg tggcgagcca gataaactgg cgattgaagc gcgcaaaacc
    21481 ggttttgatg aaatttatct gccattccgt gccgatcagg cacaacggga agcctcgcgc
    21541 tgccttaagt gcggcgagca cagcgtttgt gaatggacct gcccgctgca taaccatata
    21601 ccgcagtgga ttgaactggt gaaagccgga aacatcgacg ccgccgtcga gctttctcac
    21661 cagaccaaca ccctgccgga aattaccgga cgcgtttgcc cgcaagaccg tttgtgtgaa
    21721 ggtgcctgta ctattcgcga tgagcacggc gcagtaacta tcggtaacat tgaacgctac
    21781 atttcagatc aggcgttggc gaaaggttgg cgtcctgact taagccatgt caccaaagtg
    21841 gacaagcggg tggcgattat cggtgcgggt ccggcagggc tggcctgtgc agatgttctg
    21901 acccgcaatg gcgtggcggt gacggtgtac gatcgccatc cagaaatcgg tggcttgctc
    21961 actttcggca ttccttcttt caaactggat aaatccctgc tggcacgccg tcgggaaatc
    22021 ttcagcgcga tggggattca cttcgaactc aattgtgaag tgggtaaaga tgtctctttg
    22081 aattcgcttt tggaacaata cgacgcggtc ttcgttggcg taggcactta ccgttccatg
    22141 aaagcgggtt tacccaatga agatgcgccg ggcgtttatg acgcgctgcc gttcctcatc
    22201 gccaacacta aacaggtgat gggactcgaa gagctaccgg aagagccgtt tatcaatacc
    22261 gccggactta acgtcgtggt actgggcggc ggcgacaccg cgatggactg tgtgcgtacc
    22321 gcgctgcgcc atggcgcgag taacgtcacc tgcgcttatc gtcgtgatga agctaacatg
    22381 ccaggctcga agaaagaggt gaagaacgcc cgtgaagagg gggccaactt cgaatttaac
    22441 gtccagccgg tggcgcttga gctgaatgaa caaggtcacg tctgcgggat tcgtttcctg
    22501 cgcacgcgtc ttggcgagcc ggatgcccag ggacgtcggc gtccagtgcc ggtggaaggc
    22561 agtgaatttg tcatgccagc cgatgcggtg attatggcgt ttggcttcaa tccgcacggg
    22621 atgccgtggc tggagtcgca cggtgtaacg gtagacaaat ggggccgcat catcgcggat
    22681 gtggaaagcc agtaccgtta ccagaccacg aatccgaaaa tcttcgccgg tggtgacgcc
    22741 gtgcgtggtg cggatctggt ggttaccgca atggcagaag gacgtcatgc ggcacagggg
    22801 atcattgact ggctgggcgt aaaatcagtc aaatctcact gatagcctgc gcagacaaac
    22861 ccgacttcac agcgtaagat aattgttcat ttcgcgctgt ggagtcggta tgacgcaaca
    22921 aatcaccctc gttaaagaca aaattctctc cgataactat ttcaccctgc acaacattac
    22981 ttacgatctc acgcgcaaag atggcgaagt tatccgccat aaacgtgaag tttacgatcg
    23041 cggtaatggt gcgacgatcc tcctgtacaa cgcgaagaaa aagaccgtgg ttctgattcg
    23101 ccagttccgc gtcgctacct gggttaatgg caatgaaagc gggcaactga ttgaaacctg
    23161 cgccgggctg ctggataacg acgaaccgga agtgtgcatt cgcaaagaag cgattgaaga
    23221 gacgggctat gaagttggcg aagtccgcaa attatttgaa ctgtatatgt cgccaggcgg
    23281 tgtgactgag ctaatccact tttttatcgc cgaatacagt gacagccagc gcgctaacgc
    23341 cggtggtggt gtcgaagatg aagatattga agtgcttgag ctgccgttca gccaggcgct
    23401 ggagatgatt aaaaccggcg agatacgtga cggtaagacg gtgttattgc ttaactattt
    23461 gcaaatgtca catttaatgg actgaaaaat aacaataata tttcgttgtt tattattggc
    23521 tcaatccgac aaatccgatt gagccgcgct acctgcgcaa cgaagatacg acttgtgctg
    23581 tttgtttgaa cttctggggt cgtaccgtcc atgcgatatc gcattttcct tctctttttt
    23641 ttcgctttgt tgccgatgtc tttggtgtgg gcggcaccag cgcaacgggc gttttccgac
    23701 tggcaggtca cctgtaataa tcaaaatttc tgtgtagcgc gcaatacggg cgatcataat
    23761 ggactggtga tgaccctgag ccgcagcgcc ggggcgcata ccgatgccgt tttacgtatt
    23821 gagcgcggcg ggttgaagtc gccggatgcg tcagaagggg agatagcgcc acggctgctg
    23881 ttagatggtg agccgttggc gttaagtggt gacaagtggc ggatttcacc atggttatta
    23941 gtaaccgatg atacggcaac catcaccgcg tttttgcaga tgattcagga agggagggcg
    24001 atcaccttac gcgacggcaa tcagactatt tctctgagtg gcttaaaagc ggcgttgttg
    24061 tttattgatg cccagcaaaa gcgcgttggc agtgagaccg cgtggataaa gaaaggggac
    24121 gaaccgccgc tcagcgtacc gccagcgcct gcgctgaaag aggtcgcggt ggttaaccca
    24181 acgccgacgc cactctcact cgaagaacgt aacgatttgc tggattatgg aaactggcgg
    24241 atgaatggtc tgcgctgttc gcttgatccg ttacgtcgtg aggtgaatgt cactgcgctg
    24301 accgatgata aagcgctgat gatgattagc tgtgaggcag gggcctataa caccattgat
    24361 ttggcatgga ttgtgtcgcg taaaaagccg caggcctcgc gcccggtacg gttgcgtttg
    24421 ccgttcaaca acggtcagga gaccaatgaa ctggaactga tgaacgcaac attcgatgaa
    24481 aaatcgcgtg aactggtgac cttagcaaaa gggcgcggat taagcgattg tggcattcag
    24541 gcgcgctggc gctttgacgg tcagcgtttt cgcctggtgc gttacgccgc agaacccacc
    24601 tgcgataact ggcatgggcc agacgcctgg cccacgttgt ggatcacccg ttaaacaaaa
    24661 tggcggggac atgtagaccg gataagacgc accagcgtca catccgacaa tcagcatccg
    24721 gcgatcacca tcaggcacct ttcactccca gtaccttatg cgcttttgcc acaatattct
    24781 cggcggtaaa gccaaagaac gggaacagct tatccgccgg agctgattcc ccataacctg
    24841 tcatcccgac aattgcccct ttcaggccaa catatttgta ccagtaatcg gcaatacccg
    24901 cttctactgc cacgcgggca gaaacatttg aaggcagtac cgactcccga tatttctcat
    24961 cctgggcatc gaaaatatcg gtcgagggca gggaaactac gcgaacattg cgaccttctc
    25021 ccgctaattt ctctgccgct tgcagggtga tttccatctc tgaaccggtg gcaatcagaa
    25081 taatatctgg cttaccgccg ctgtctttca gcacataacc gccacgagca atctctttaa
    25141 cctgatccgg tgttcgttct acctgtgcca gattctgcct ggagaggatc agtgctgtcg
    25201 gtccgttgtg gcgctcaacc gccagcttcc agccaaccgc cgcttccacc tgatcgcacg
    25261 gtcgccaggt gctgaaattt ggcgttaagc gcagactagc cagttgctca acagcctggt
    25321 gcgtcggacc atcttcgccc agaccaattg agtcgtgggt ataaaccata atctgccgcg
    25381 ctttcatcag tgccgccatc cgcgcggcgt tacgggcgta ttcaacaaac atcaggaacg
    25441 tcgcggtata cggcacaaag ccgccgtggt gcgcgatgcc gttggcgata gcggtcatac
    25501 caaattcacg caccccgtag tgaatgtagt tgcccgccgg atcttccttc agcgaaacag
    25561 aacctttcca gatggtcagg ttgctgggag ccagatccgc cgaaccgccg agcaactcag
    25621 gcagcatcgg cccgtaagcg ttaagcgtat tttgcgaagc cttacgggta gcgattttcg
    25681 ccggattcgc ctgcaactca ttgatatatt tctgagtcgt tttctcccag tccttcggca
    25741 aaccgccgct catccgacgg gtaaactctt ctgccagttg cggatgagcc tttttatagg
    25801 cggcaaactt ctcattccag ctctgctgcg ctttttcgcc tttttcgcgg gcatcccagg
    25861 cgtgataaat ctctttaggg atctcaaatg gcggatggtg ccagcccagt ttttgccgtg
    25921 ccagagctac ttcttcttcc cccagcggtg cgccgtgcgc ctcttcctta cctgctttat
    25981 tcggcgaacc aaagccaatc accgtacggc agataatcag cgacggctta tctttcacgc
    26041 tttgcgcttc aaggatcgct tccttcaccg cctgcggatc gtggccgtcg atctcgtgga
    26101 ccacatgcca gtgataggct tcaaaacgtt ttgccgtatc gtcggtaaac cagccttcgg
    26161 tttcaccgtc gatggaaata ccgttgtgat cgtaaaaacc aatcagcttg cccagcccca
    26221 gcgtgcccgc cagcgaacag acttcgtgag agataccttc catcaggcag ccgtcgccca
    26281 taaacacata ggtgaagtga tcgacaattt catgatccgg ctgattaaat tgcgccgcca
    26341 gcgtacgctc tgctatcgcc agcccgacgg cgttcgccaa accttgtcca agaggaccgg
    26401 tggtggtttc aacacctggc gtataaccga tttccgggtg accaggggtt ttcgaatgca
    26461 actgacggaa gttcttcagt tcttccagtg gcaggtcgta accggtcaga tgcagcaaac
    26521 tgtagagcag catcgacgcg tgaccgttgg aaagaataaa gcggtcgcga tcataccagg
    26581 ttgggtcggt agggttatgt ttaagaaaat cgttccacag cacttcggca atatcagcca
    26641 tgcccatcgg cgcgccggga tgaccagaat tggctttttg taccgcatcc atactgagtg
    26701 cgcgaatcgc attggcaagg tcttttcggg acatataaca ctccgtggct ggtttatagt
    26761 ttggcggcaa gaagatcttc cagtttgcgt tgatcaacgg cgaacagacg aatgccttca
    26821 gacagttttt ctaccgccat cgcatcctga ttgtgctccc aacggaactc tgcttcgctc
    26881 atgggagctg ggcgtgggaa cgtctgagaa ggtgggatta atttacgtac cactggcgaa
    26941 actttttcct gtagctcctt cagcaaattc ggtgcgatag tcagtcggtc gcagccggtt
    27001 aaggcgagga tttgttcggt gcgacggaag ctcgcgccca tcacaatggt ttcatagtgg
    27061 tgttgcttat agtagtcgta gatattgcgt actgatttaa cgcctggatc ttcttccacc
    27121 acatacgggt ccatcggctt gcgtgcctga taccagtcat aaatacgccc gacaaatggc
    27181 gaaatcagaa aaacgcctgc ttctgcacag gcccgcgcct gtgcaaaaga aaacagcagc
    27241 gtcaggttgc agttaatacc ttctttttcc agctcttctg ccgcgcgaat tccttcccag
    27301 gtcgaagcca gcttgatcag aatgcgcgat ttctcaacgc cttgttgctg atacaaatcc
    27361 accagatggc gcgccttctc aatactcttt tctttatcaa aagagaggcg tgcatcaact
    27421 tctgttgaca cgcgaccggg tacgattttg agaatttcag caccgaaatt gaccgccagt
    27481 ttgtcacacg ctgcgaccac ctgttgttcc tgggtcttgc catttttttt accccaggcg
    27541 atagcatcgt ctattaaatg ctcatattgt gataatccgg cagccttgag taacagcgaa
    27601 ggattggtgg tggcatcctg gggatgataa tggcgaatgg actcaatatc gccgctgtct
    27661 gccacgacag tggtgaactg tttgatgccg tctaactcgt tcataggaaa tactccttga
    27721 aaagtaaagt gttagatgag tgcgttaatt cacacttctg agaaatttcg ctaaacgcat
    27781 caaaaaagca tagcagacag gcatggtatt gctggattaa gcaggtaaca tcagtgttat
    27841 atgattatta ccaaaacatt atattaatgg tgagagtttg gacttgctca aagtctgtag
    27901 actccggcag ggtaataatg tgcgccacgt tgtgggcagg ggctgttgcc cacacaattt
    27961 atttgtgaac gttacgtgaa aggaacaacc aaatggatga ccagttaaaa caaagtgcac
    28021 ttgatttcca tgaatttcca gttccaggga aaatccaggt ttctccaacc aagcctctgg
    28081 caacgcagcg cgatctggcg ctggcctact caccaggcgt tgccgcacct tgtcttgaaa
    28141 tcgaaaaaga cccgttaaaa gcctacaaat ataccgcgcg cggtaacctg gtagcggtga
    28201 tctctaacgg tacggcggtg ctggggttag gcaacattgg cgcgctggca ggcaaaccgg
    28261 tgatggaagg caagggcgtt ctgtttaaga aattcgccgg gattgatgta tttgacattg
    28321 aagttgatga actcgacccg gacaaattta ttgaagtcgt cgctgcgctc gaaccgacct
    28381 tcggcggcat caacctcgaa gacattaaag cgccagaatg tttctatatt gaacagaaac
    28441 tgcgcgagcg gatgaatatt ccggtattcc acgacgatca gcacggcacg gcaattatca
    28501 gcactgccgc catcctcaac ggcttgcgcg tggtggagaa aaacatctcc gacgtgcgga
    28561 tggtggtttc tggcgcgggt gccgcagcaa tcgcctgtat gaacctgctg gtagcgctgg
    28621 gtctgcaaaa acataacatc gtggtttgcg attcaaaagg cgttatctat cagggccgtg
    28681 agccaaacat ggcggaaacc aaagccgcat atgcggtggt ggatgacggc aaacgaaccc
    28741 tcgatgatgt gattgaaggc gcggatattt tcctcggctg ttccggcccg aaagtgctga
    28801 cccaggaaat ggtgaagaaa atggcccgtg cgccaatgat cctggcgctg gcgaacccgg
    28861 aaccggaaat tctgccgccg ctggcgaaag aagtgcgtcc ggatgccatc atctgtaccg
    28921 gtcgttccga ctacccgaac caggtgaaca acgtcctttg cttcccgttt atcttccgtg
    28981 gcgcgctgga cgttggcgca accgccatca acgaagagat gaaactggcg gcggtacgcg
    29041 cgattgcaga actggcccat gcggaacaga gtgaagtggt ggcttcagcg tatggcgatc
    29101 aggatctgag ctttggtccg gaatacatca ttccaaaacc gtttgatccg cgcttgatcg
    29161 ttaagatcgc tcctgcggtg gcgaaagcgg cgatggagtc gggcgtggcg acgcgtccga
    29221 ttgctgattt cgacgtctac atcgacaagc tgacggagtt cgtttacaaa accaacctgt
    29281 ttatgaagcc gattttctcc caggctcgca aagcgccgaa gcgcgtagtt ctgccagaag
    29341 gggaagaggc gcgcgttcta catgccactc aggaactggt aacgctggga ctggcgaaac
    29401 cgatccttat tggtcgtccg aacgtgatcg aaatgcgcat tcagaaactg ggcttgcaga
    29461 tcaaggcggg cgttgatttt gagatcgtca ataacgaatc cgatccgcgc tttaaggagt
    29521 actggaccga atacttccag atcatgaagc gtcgcggtgt cactcaggag caggcgcagc
    29581 gtgcgctgat cagtaacccg acagtgatcg gcgcgatcat ggttcagcgt ggcgaagccg
    29641 atgcaatgat ttgcggtacg gtgggcgatt atcatgaaca ctttagcgtg gtgaaaaatg
    29701 tctttggtta tcgcgatggc gttcacaccg caggtgcaat gaacgcgctg ctgttgccga
    29761 gtggtaacac ctttattgcc gatacctacg tcaatgatga gcctgatgca gaagagctgg
    29821 cggagatcac cttgatggcg gcagaaactg ttcgtcgttt tggtattgag ccgcgtgtgg
    29881 ctctgttgtc gcactccaac tttggttctt ctgactgccc gtcgtcgagc aaaatgcgtc
    29941 aggcgctgga actggtcagg gaacgtgcgc cagaactgat gattgatggt gaaatgcacg
    30001 gcgatgcagc gctggtggaa gcgattcgca acgaccgtat gccggacagc cctttgaaag
    30061 gttccgctaa tattctggtg atgccgaaca tggaagctgc ccgcattagt tacaacttac
    30121 tgcgtgtttc cagctcggaa ggtgtgactg tcggcccggt gctgatgggg gtggcgaagc
    30181 cggttcacgt gttaacgccg atcgcatcgg tacgtcgtat cgtcaacatg gtggcgctgg
    30241 ccgtggttga agcgcaaacc caaccgctgt aattcttttt taactctcac gcttaccctg
    30301 aatattcagg gtaagcggtt tagctgcaat atattagtaa agtttattac tgagtttgcg
    30361 aataataaaa aaatcagtat ataaaatatc tcgatattat tttatttata ttcatgcgtt
    30421 gtatatgaaa atttatgcac cacagcaaat atctctccat tcttagtgat ctacctcacc
    30481 ttttaaacgc gcttgccgaa ttttgttatt tactctgacg aaaaattgtc acgatacacg
    30541 aaagtttttc acaggcggcg actcatggat aaagaacgca tcattcagga atttgtgccc
    30601 ggtaaacagg tcacactggc gcatctcatc gcgcatcccg gcgaggaact ggcgaagaaa
    30661 atcggcgttc cggatgcggg cgcaatcggc attatgacgc taactcccgg agaaacggcg
    30721 atgatcgccg gtgatttagc gttgaaagcc gccgatgtgc atatcggttt tctcgatcgt
    30781 tttagtggcg cgctggtgat ttatggctcg gtgggcgcag tagaagaagc gttatcacaa
    30841 accgtcagtg gtttaggacg cttattaaat tatacgcttt gtgaaatgac caaaagttaa
    30901 tacgaggcat tcatgaaacg aattgcgttt gtgggtaccg tcggggcagg aaaaacaacg
    30961 ttatttaatg cgttgcaggg gaattatacc ctcgcaagaa aaacacaggc cgtggaattt
    31021 aatgataatg gcgatattga tacgccgggt gaatatttta gccatccccg ctggtatcac
    31081 gccttaatta ccacgctaca ggatgtggat atgctgatct atgtccacgg cgcgaatgac
    31141 ccggaaagtc ggttgcctgc cgggttgctg gatattggcg tcagcaaacg gcaaatcgcc
    31201 gtcatcagta aaacggacat gccagatgct gacgtcgccg caacgcgaaa gttattgctt
    31261 gagacgggct tcgaagagcc gattttcgag ctaaacagcc acgacccgca aagcgtgcag
    31321 caactggtgg attatctggc atctctcacc aaacaggagg aagcaggtga aaaaactcat
    31381 cacagcgaat gatattcgtg aagcacacgc gcgcggcgaa ctggcaatgt ccgtggttct
    31441 gcgcgccagc attattaccc cggaagctcg tgaagtggct gatctgttgg gttttaccat
    31501 caccgaatgt gatgaatcga tcccggtaac ggcgtctgtt cccgccagcg catcagccga
    31561 taaaaccgaa agccagcgca tccgtgaaac cattatcgcc caactgccgg aaggtcagtt
    31621 taccgaaagc ctggtcgcgc agctgatgga aaaagtgatg aaggaaaaac agtcgctgga
    31681 acagggtgca ctgcagccga gctttaaatc ggtgaccggc aaaggcggca tcaaagttat
    31741 tgatggcagc agcgtcaagt ttggtcgttt cgatggcgcg gaaccgcact gcgtaggctt
    31801 gactgatctc gtgaccggag acgacggcag cagtatggcc gctggtttca tgcagtggga
    31861 gaacgccttc tttccgtgga ccctgaacta cgacgaaatc gacatggtgc tggaagggga
    31921 gctgcatgtt cgccacgaag gcgaaactat gatcgccaaa gcgggcgatg tgatgtttat
    31981 cccgaaaggc tccagcatcg aatttggtac gacatccagc gtgaaattcc tgtatgtcgc
    32041 ctggccggct aactggcaat ccttatgaaa gatttcatca ccgaagcatg gctaagagcg
    32101 aaccatacgc tcagcgaagg cgcagagatc catctccctg cggacagtcg cctgacgccc
    32161 tctgcccggg agttactgga aagccgccat ctgcgcatca agtttattga cgagcagggc
    32221 cgcctgtttg ttgacgatga acagcagcag ccgcagcccg ttcacgggct gaccagtagc
    32281 gatgaacatc cgcaggcgtg ctgcgaactg tgccgccagc cggtggcaaa aaagccggat
    32341 acgctgactc acctgtcggc ggaaaaaatg gttgccaaaa gcgatccgcg tctgggtttt
    32401 cgcgctgttc tcgacagcac cattgcgctg gcagtgtggc tgcaaattga actggcagaa
    32461 ccgtggcagc cgtggctggc ggacatccgc tcgcgtcttg gcaacattat gcgtgccgat
    32521 gcgctggggg aaccgctggg cgagcaagcg attgtcgggc tttctgacga agatctgcat
    32581 cggctttctc accagccgct gcgttatctc gaccacgatc atctggtgcc ggaagccagc
    32641 cacgggcgcg atgcggcgtt gctcaatctg ctacgcacca aagtgcggga aacagaaacc
    32701 gtagcggcgc aggtctttat cacccgcagc tttgaagtat tacgcccgga cattttgcag
    32761 gcgctgaacc gcctttccag cacggtctac gtgatgatga tcctgagcgt aacgaagcag
    32821 ccgctaacgg tgaagcagat ccaacaacga ctgggggaaa cgcaatgatt attaaacgtt
    32881 gtcgtgaact ggcgttgcga gcgcccgcca gagtagtttt tccggatgcg ttagatcaac
    32941 gtgtgctgaa agctgcgcaa tatttacatc aacaaggtct ggcaacgccc attctggtcg
    33001 ccaatccgtt tgaacttcgt cagtttgcgc tcagtcacgg cgtggcgatg gacgggctac
    33061 aggtgataga tccgcatggc aacctcgcaa tgcgggaaga atttgctcat cgctggctgg
    33121 cccgcgcggg cgaaaaaacg ccgccggatg cgctggaaaa acttaccgat ccgctgatgt
    33181 tcgccgctgc aatggtcagc gccggtaaag cggatgtctg tatcgcgggc aacctctctt
    33241 ccacggcgaa tgtgctgcgt gccggattac gcattatcgg cttgcagcca ggctgtaaaa
    33301 cgctctcatc cattttcctg atgctgccac agtacagcgg tccggcgttg ggttttgccg
    33361 attgcagcgt ggtgccacag ccgacggcgg cacaactggc ggatatcgcg cttgccagcg
    33421 ccgaaacctg gcgcgccatc accggagaag aaccgcgcgt ggcgatgctg tcgttttcca
    33481 gcaacggtag tgcccgtcac ccctgtgttg ccaacgtcca gcaggcgaca gaaatcgtcc
    33541 gtgagcgcgc accaaagctg gttgtcgatg gcgagttgca gtttgacgcc gccttcgtgc
    33601 cggaagtggc ggcgcaaaaa gcgcctgcca gcccgttaca gggcaaagct aatgtgatgg
    33661 tttttccgtc gctggaagcc ggaaatattg gctacaaaat cgcacaacga cttggcggat
    33721 atcgtgccgt cgggccattg atacaaggac ttgccgcgcc gatgcacgat ctctctcgtg
    33781 gttgtagcgt gcaggaaatt atcgaactgg cgctggtggc agctgtgccg cgtcagacag
    33841 aagtgaaccg cgaaagcagt ttacaaacac tggttgaatg aacggtcccg ttctggaccc
    33901 tgataaagag gaaagcacaa tggaagcatt aggaatgatc gaaacccggg gcctggttgc
    33961 actgattgag gcttctgacg cgatggttaa agctgcgcgc gtcaagctgg ttggtgttaa
    34021 gcagattggc ggcggcctgt gtactgccat ggttcgtggt gatgttgcag cctgtaaagc
    34081 cgcgaccgat gcaggtgccg cagcggcaca gcgtatcggc gagctggtat ctgtacacgt
    34141 tatcccgcgt ccgcacggcg acctggaaga agtcttcccg atcggcctga aaggcgatag
    34201 cagcaacctg taatcaccct gtgtgacgtc gattcgggcg tcacgctctc tcctttttca
    34261 ttttaccttc tgcggagggt agggggagct tttacctgaa atacgccacg gaggcgggta
    34321 tgaaactggc agtcgtcact ggacaaattg tttgtaccgt acgccatcac ggactggcgc
    34381 atgacaaatt gctgatggtg gaaatgattg atccacaagg taatcctgac gggcaatgcg
    34441 ccgtcgccat cgacaatatt ggcgcgggaa ccggggagtg ggtgttactg gtgagtggca
    34501 gttccgcccg ccaggcgcat aaaagcgaaa cgtcaccggt cgatctgtgc gtgattggca
    34561 ttgtcgatga ggtggtgtct ggcggtcagg tcattttcca caaataaggc agaacatcat
    34621 gaatcaacag gatattgaac aggtggtgaa agcggtactg ctgaaaatgc aaagcagtga
    34681 cacgccgccc gccgccgttc atgagatggg cgttttcgcg tccctggatg acgccgttgc
    34741 ggcagccaaa gtcgcccagc aagggttaaa aagcgtggca atgcgccagt tagccattgc
    34801 tgccattcgt gaagcaggcg aaaaacacgc cagagattta gcggaacttg ccgtcagtga
    34861 aaccggcatg gggcgcgttg aagataaatt tgccaaaaac gtcgctcagg cgcgcggcac
    34921 accaggcgtt gagtgcctct ctccgcaagt gctgactggc gacaacggcc cgaccctgat
    34981 tgaaaacgca ccctggggcg tggtggcttc agtgacgcct tccactaacc cggcggcaac
    35041 cgtaattaac aacgccatca gcctgattgc cgcgggcaac agcgtcattt ttgccccgca
    35101 tccggcggcg aaaaaagtct cccagcgggc gattacgctg ctcaacctgg cgattgttgc
    35161 cgcaggcggg ccggaaaact tactggttac cgtaacaaat ccggatatcg aaaccgcgca
    35221 acgcttgttc aagtttccgg gcatcggcct tttggtggtg accggcggcg aagcggtagt
    35281 agaagcggcg cgtaaacaca ccaataaacg tctgattgcc gcaggcgctg gcaacccgcc
    35341 ggtagtggtg gatgaaaccg ccgacctcgc ccgtgctgct cagtccatcg tcaaaggcgc
    35401 ttctttcgat aacaacatca tttgtgccga cgaaaaggta ctgattgttg ttgatagcgt
    35461 agccgatgaa ctgatgcgtc tgatggaagg ccagcatgcg gtgaaactga ccgcagagca
    35521 ggcgcagcaa ctgcaatcgg tgttgctgaa aaatatcgac gagcgcggaa aaggcaccgt
    35581 cagccgtgac tgggttggtc gcgatgcggc gaaaatcgcg gcggcaatcg gccttaaagt
    35641 tccggaacaa acgcgactgc tgtttgtaga aaccaccgca gaacatccgt ttgccgtgac
    35701 cgaactgatg atgccggtgc tgcccgtcgt gcgcgtcgcc aacgtggcgg atgccattgc
    35761 gctggcggtg aaactggaag gcggttgcca ccacacggcg gcaatgcact cgcgcaatat
    35821 cgaaaacatg aaccagatgg cgaacgccat tgataccagc attttcgtta agaacggacc
    35881 gtgtattgcc gggctggggc tgggcgggga aggctggacc acgatgacca tcaccacgcc
    35941 aaccggtgaa ggggtaacca gcgcgcggac gtttgtccgt ctgcgtcgct gtgtattagt
    36001 cgatgcgttt cgcattgttt aaggagtaac cgatggcgca cgatgaacaa tggctcaccc
    36061 cacgtctgca aacggcggca acgctgtgta accagacgcc cgccgcgacg gaatctccgc
    36121 tgtggctggg ggtggatctg ggcacctgcg atgtggtgtc gatggttgtc gaccgcgacg
    36181 gtcagccggt ggcggtatgc ctcgactggg ccgatgtggt ccgcgacggc atcgtctggg
    36241 atttcttcgg tgcggtcacc attgttcgtc gccatctcga cacccttgag cagcaattcg
    36301 gtcgccgttt tagccatgcg gcgacctcat ttcctcctgg tacggacccg cgtatttcca
    36361 tcaacgtgct ggagtctgcc ggactggaag tgagccatgt gctggatgag ccaaccgcag
    36421 ttgcggatct gctgcaactg gacaacgccg gtgtagtgga tatcggcggc ggcactaccg
    36481 gcattgccat cgtgaaaaag ggcaaagtga cgtactcggc ggatgaagcc accggcggac
    36541 atcacatctc tctgactctc gccggaaatc gccgtatttc gctggaagag gcagagcagt
    36601 acaaacgcgg tcacggtgac gagatttggc ccgcggtgaa accggtgtac gaaaaaatgg
    36661 cggacattgt ggcccgtcat attgaagggc agggcattac ggatttatgg ctggcgggcg
    36721 gttcctgtat gcaaccgggc gtagcggcgc tgttttgcaa acaatttccg gcgttacagg
    36781 tgcatttacc gcagcacagt ttgtttatga ccccgctggc aatcgccagt agtgggcgag
    36841 agaaagcgga ggggctatat gcaaaatgaa ttgcagaccg cgctctttca ggcgttcgat
    36901 accctgaatc tgcaacgggt aaaaacattt agcgttccac cggtgacgct ttgcggtccg
    36961 ggcgcggtga gcagttgtgg gcagcaagcg caaacgcgtg ggttgaaaca tctgttcgtg
    37021 atggcagaca gctttttgca tcaggcaggg atgaccgctg ggctgacgcg tagcctggcc
    37081 gttaaaggta tcgccatgac gctctggcca tgtccggtgg gcgaaccgtg catcaccgac
    37141 gtgtgtgcag ccgtggcgca gttgcgtgaa tcaggttgtg acggggtgat cgcgtttggc
    37201 ggcggctcgg tgctggatgc ggcgaaagcc gtggcgttgc tggtgacgaa cccggatagc
    37261 acgctggcag aaatgtcaga aaccagcgtt ctgcaaccgc gcctgccgtt gattgccatt
    37321 ccaacgaccg ccggaaccgg ctctgaaacc accaacgtga cggtgattat cgatgcggta
    37381 agcgggcgca aacaggtgtt agcccatgcc tcgctgatgc cggatgtcgc gattctcgac
    37441 gctgtgctaa ccgaaggcgt gccgtcgcat gtcacggcga tgactggcat tgatgcgtta
    37501 acccatgcca ttgaagcgta cagcgcgctg aacgctacac cgtttaccga cagcctggcg
    37561 attggcgcca ttgcgatgat tggtcaatcg ctgccgaaag cggtgggcta cggtcacgac
    37621 cttgtcgccc gcgagagcat gttgctggct tcatgtatgg cgggaatggc gttttccagc
    37681 gccgggcttg ggttatgcca cgcgatggcg catcagccag gggcggcgct gcatattccg
    37741 cacggtctgg cgaacgccat gttgctgcca acggtgatgg aatttaaccg gatggtttgt
    37801 cgtgatcggt ttagtcagat tggtcgggcg ctgcgaacta aaaaatccga cgatcgtgac
    37861 gctattaatg cggtaagtga gctgatagcg gaagttggga tcaacaagcg gctggctgat
    37921 gtgggtgcaa caaccgggca ttacggtgca tgggcgcagg ccgcgcagga agatatttgt
    37981 ctgcgcagta acccgcgtac cgccagcctc gagcagattg tcggcctgta cgcagcggcg
    38041 caataaatgc cggatgcgac gcttgccgcg tcttatccgg cctacgggat tgcacatgta
    38101 gggcggataa ggcgttcacg ccgcatccgc cagtggcgcg gtgcaattgc cggatgcgac
    38161 gcttgccgcg tcttatctgg ccttcgggat tgcacatgta gggcggataa ggcgttcacg
    38221 ccgcatccgc caataaataa caactaacag ggagtaaagg cgatgggaat taacgaaatc
    38281 atcatgtaca tcatgatgtt ctttatgctg atagctgccg tagacaggat cctgtcgcag
    38341 ttcggcggtt ctgctcgttt cctcggtaag ttcggtaaaa gtatcgaagg atccggcggt
    38401 cagttcgaag aaggctttat ggcaatgggc gctctgggcc tggctatggt cggtatgacc
    38461 gcactggcac cggtactggc ccacgttctc ggaccggtga ttatcccggt ttacgaaatg
    38521 ctcggcgcaa acccgtcaat gttcgccgga acactgctgg cgtgcgatat gggcggcttc
    38581 ttcctcgcca aagagctggc gggcggtgac gtagcagcgt ggctatactc tgggttaatt
    38641 ctcgggtcga tgatggggcc aacgattgtg ttttccattc cggtggcgct cggcattatc
    38701 gaaccttctg accgtcgtta tctggcgctc ggcgtgctgg cgggcatagt gaccattccg
    38761 attggctgta tcgctggtgg tctggtagcg atgtactccg gtgtgcagat caacggccag
    38821 cctgttgaat tcacctttgc gctgatcctg atgaacatga tcccggtact tatcgttgcg
    38881 gtgctggtgg cgctggggct gaaattcatc ccggaaaaaa tgatcaacgg cttccagatc
    38941 ttcgccaaat tcctcgttgc attgatcacc ctcggtcttg ccgctgcggt agtgaaattc
    39001 ctccttggct gggaactgat cccgggcctt gatcctatct ttatggcccc tggcgataaa
    39061 cccggtgaag tgatgcgcgc cattgaagtt atcggctcga tctcctgcgt tctgttaggg
    39121 gcgtatccaa tggtactgct gctgactcgc tggtttgaaa aaccgctgat gagcgtcggt
    39181 aaggtgctga atatgaacaa tatcgcggca gccggcatgg tggcaacgct tgccaacaac
    39241 attccgatgt ttggcatgat gaagcagatg gatacccgcg gcaaagtcat caactgtgcc
    39301 ttcgccgttt ccgctgcttt cgcgctgggc gaccatttag gcttcgccgc tgccaacatg
    39361 aacgccatga tcttcccgat gattgtcggc aaattgatcg gcggcgtaac ggcaattggc
    39421 gtggcgatga tgctggtgcc aaaagaagac gcgagcgcgg ctaaaaccga agcggaggcg
    39481 caatcgtgaa cactcgccag ctactgagcg tcggtatcga tatcggcacc accaccaccc
    39541 aggtgatctt ctcccacctg gagctggtta accgtgcggc ggtgtcgcag gtgccgcgct
    39601 acgaattcat caaacgcgaa attagctggc aaagcccggt gttctttacc cctgtcgata
    39661 aacagggtgg tttaaaagaa gcggaactga aaaccttaat cctcgagcaa tatcaggctg
    39721 cgggcattgc gccggaaagc gttgattctg gtgccatcat catcaccggt gaaagcgcga
    39781 aaacccgcaa cgctcgcccg gcggtgatgg cgctctctcg gtcgctgggc gattttgtcg
    39841 tcgccagcgc cgggccgcat ctcgaatccg tgatcgccgg tcacggtgcc ggggcgcaaa
    39901 ccctttctga acaacggctg tgtcgggtac tgaatatcga catcggcggt ggcaccgcga
    39961 actacgccct gttcgatgcc ggaaaaatca gcggcactgc ctgcctcaac gtcggcggtc
    40021 gcctgctgga aaccgacagc caggggcgcg tggtttacgc tcataaaccg gggcagatga
    40081 ttgtggatga gtgcttcggc ccaggcactg acgcccgttc gctgaccggc gcgcaattgg
    40141 cgcaggttac ccgccggatg gcggaactga ttgtcgaagt gattgacgga acgctctcgc
    40201 cgctcgcgca ggcattgatg caaaccggtt tgctgcccgc aggtgttacg cccgaaatca
    40261 ttacgctttc tggcggggta ggcgaatgtt atcgccacca gcccgccgac ccgttctgtt
    40321 ttgccgatat cggcccgctt ctggcaacgg cgctgcatga ccatccgcgt ctgcgtgaga
    40381 tgaacgtgca gtttccggcg caaaccgtgc gcgccacggt gattggcgcg ggtgcacata
    40441 ccctttcgct ctctggcagc acaatatggc tggagggcgt acaactgccg ctgcgcaatt
    40501 tgccggtggc gatcccgatt gatgaaacgg atctggtcag tgcctggcaa caggcgctga
    40561 ttcaactgga tctttgcccc aaaactgacg cgtacgtgct ggcgcttccc gcctcgctgc
    40621 ctgtgcgtta cgccgcggta ctgacggtca tcaacgcgct ggtcgatttc gtcgcgcgtt
    40681 ttccgaatcc gcatcccctg ctggtggtgg ccgggcagga ctttggtaaa gctctgggca
    40741 tgttgttgcg cccacagcta caacaactcc cgttggcagt cattgacgaa gtgattgtcc
    40801 gcgcggggga ctatatcgac attggtacgc ctctttttgg cggatcggtt gtgccggtga
    40861 cggtgaaatc actcgcattt ccttcctgag ggaacgactt atgaaactaa agaccacatt
    40921 gttcggcaat gtatatcagt ttaaggatgt aaaagaggtg ctggctaaag ccaacgaact
    40981 gcgttcgggg gatgtgctgg cgggcgttgc tgcggcaagc tcacaggagc gcgtggcggc
    41041 aaagcaggtg ttgtcggaaa tgactgtagc ggacatccgc aataatccgg tgattgccta
    41101 tgaagatgac tgcgtgacgc ggctgattca ggacgacgtt aacgaaacgg cctacaacca
    41161 gattaaaaac tggagcatca gcgaactgcg tgagtatgtg ctgagcgatg aaaccagcgt
    41221 ggatgacatt gcctttaccc gcaaagggct gacctcggaa gtggtggcgg cggtagcgaa
    41281 gatttgctcc aacgcggacc tgatctacgg cgcgaagaaa atgccggtga tcaaaaaggc
    41341 caataccacc atcggtattc cgggcacctt cagcgcccgc ttgcagccga acgatacccg
    41401 tgacgacgtg caaagtatcg ccgcgcaaat ctacgaaggg ctttccttcg gggtgggcga
    41461 tgcggtgatc ggcgttaacc cggtgactga cgacgtggaa aacttaagcc gcgtgttgga
    41521 taccatctat ggcgtgatcg acaaattcaa catcccaact cagggctgca tactggcgca
    41581 cgtcactacc caaatcgaag cgattcgtcg cggcgcacca ggcgggctga ttttccagag
    41641 tatctgcggc agcgaaaaag ggctgaaaga gtttggcgta gagctggcga tgctcgatga
    41701 agcacgcgca gtgggcgcgg agttcaaccg tatcgccggg gaaaactgcc tctacttcga
    41761 aaccggacaa ggttcggcgc tgtctgctgg cgcgaacttc ggcgcagacc aggtgacgat
    41821 ggaagcgcgt aactatgggc tggcgcgtca ttacgatccg tttatcgtca acactgtggt
    41881 cggctttatt gggccggagt atctctacaa cgaccgccag attatccgcg caggcttaga
    41941 agatcacttt atgggcaaac tgagcggcat ctctatgggc tgtgactgct gctacaccaa
    42001 ccacgctgac gctgaccaga acctcaacga aaacctgatg atcctgctcg ccaccgcagg
    42061 ctgcaactac atcatgggga tgccgctggg cgatgacatc atgctcaact atcagaccac
    42121 cgcattccac gacactgcca ctgtgcgtca gttactgaat ctgcgcccgt caccggagtt
    42181 tgaacgctgg ctggaaagca tgggcattat ggcaaacggt cgcctgacca aacgggcggg
    42241 cgatccgtca ctgttcttct gatgacgcgg agataacaca tcatggatca aaaacagatt
    42301 gaagaaattg tacgcagcgt gatggcgtca atgggacaag cggcccccgc gccgtcagaa
    42361 gcaaagtgcg ccaccaccac ctgtgcggca ccggtgacct cggaaagctg cgcgctggat
    42421 ttaggttctg cggaagcaaa agcgtggatt ggtgttgaaa acccgcatca cgcagacgta
    42481 ttaacagaac tgcgtcgcag caccgtggcc cgcgtttgta ccggtcgtgc cggtccgcgt
    42541 ccgcgcaccc aggcgttgct gcgtttcctg gccgatcact ctcgttcgaa agataccgtt
    42601 ctgaaagaag taccggaaga gtgggtgaaa gcgcagggct tgctggaagt ccgctccgaa
    42661 atcagcgaca aaaatctcta cctgactcgc ccggatatgg gccgccgcct gtgtgcagaa
    42721 gctgttgaag cgctgaaagc acagtgtgtt gctaatccgg acgtgcaggt cgttatttct
    42781 gatggcctgt caactgatgc gatcaccgtg aactacgaag agatcctgcc gccgctgatg
    42841 gcgggcctga agcaagccgg gctgaaagtc ggtacgccat tctttgtacg ttatggtcgc
    42901 gtgaagattg aagatcagat cggtgagatc ctcggcgcga aagtagtgat cctgctggtg
    42961 ggcgaacgtc cggggttggg gcagtcagaa agcctctcct gctacgccgt ttactcgccg
    43021 cgtatggcga ccaccgttga ggctgaccgc acttgtatct ctaacattca ccagggcggc
    43081 acgccgccgg ttgaagccgc agccgtcatt gtggatttgg cgaaacgtat gctggagcag
    43141 aaagcatccg gcatcaacat gacccgataa ggaggcatca tgccagcttt agatttgatt
    43201 cgaccgtcgg taaccgccat gcgggtgatt gcctccgtta acgccgaatt tgcacgtgaa
    43261 ctgaaattgc cgccgcatat tcgtagcctc gggctgattt ctgctgattc agatgacgtc
    43321 acctacattg cggctgacga agcgaccaag caggcgatgg tcgaagtggt atatggtcgc
    43381 tcgctgtatg cgggcgctgc acacggcccg tcaccgactg ccggtgaggt gctgattatg
    43441 cttggtggac caaacccggc ggaagtgcgt gctggtctgg atgcgatggt tgcgaatatt
    43501 gaaaatggcg ctgctttcca gtgggctaat gacgcagaaa acacagcctt cctggcacat
    43561 gtagtttcgc gtaccggttc ttatctctca tcaaccgccg ggatcacgct tggcgatccg
    43621 atggcgtatc tggtggcacc gccgctggaa gcgacctacg gcattgatgc agcgttgaaa
    43681 tctgccgacg tgcagctggt gacctatgtc ccgccaccgt ctgaaaccaa ctactcggca
    43741 gcatttttaa ccggtagcca ggccgcgtgt aaagcagcct gtaacgcctt taccgatgca
    43801 gtgctggaaa tcgcgcgtaa tccaatccag cgtgcgtaac ggaggttgcc gatgatcaat
    43861 gcactgggat tgctggaagt ggacggcatg gtcgccgcga tagatgcagc tgatgccatg
    43921 ctcaaagcag ctaacgttcg tctgctcagt cacgaagtgc ttgaccctgg tcgcctaacg
    43981 ctggtggtgg aaggcgatct ggcggcgtgt cgtgcggcgc tggacgcagg ttgtgctgcc
    44041 gcgatgcgta ccgggcgtgt catcagccgc aaggagatcg gtcggccaga cgatgacacc
    44101 cagtggctgg ttactggctt taaccgccag cctaagcaac ccgtaaagga acccgacgcg
    44161 ccagttatcg tcgcggaatc tgctgacgag ttgttggcgc tgttaacatc agtacgtcag
    44221 ggaatgacgg caggagaagt ggctgcccac tttggctggc cgctggaaaa agccagaaat
    44281 gcgctcgaac agctcttttc tgccgggacg ttacgtaaac gcagtagtcg ttaccgtctc
    44341 aagccccatt aacctgtcgg aggtgccggg tgtcctacaa cacccggcat taacatcatg
    44401 aaaaagaccc gtacagccaa tttgcaccat ctttatcatg aacccttacc cgaaaacctg
    44461 aagctcacgc cgaaggtcga agtggataat gttcatcaac gacagacaac ggacgtctat
    44521 gaacatgctt tgacaattac cgcctggcag cagatttacg atcagctgca tccgggcaag
    44581 tttcatggtg aatttacgga aattctactc gatgatattc aggtttttcg tgaatacact
    44641 ggtctggcgc tgcgtcagtc gtgcctggtc tggccgaact cgttctggtt tggcattccg
    44701 gcgacgcgcg gtgagctggg atttatcggt tcgcaatgtc tgggaagcgc agaaattgcg
    44761 acgcgcccgg gtggaaccga gtttgaatta agtacgccgg acgattacac gatccttggc
    44821 gtagtgcttt ctgaagatgt catcactcgt caggctaact ttttgcataa tccggatcgg
    44881 gtattacata tgctgcgtag ccagtcggcg ctggaagtga aagagcagca taaagccgct
    44941 ctgtggggct ttgtccaaca ggcgctggcg acgttttgcg agaacccgga aaatctccat
    45001 cagcctgcag tgcgaaaagt gctgggggat aatttgctca tggcgatggg ggcgatgctg
    45061 gaagaagcgc agccgatgat gacggcggaa agcatcagcc atcagagtta ccgccgattg
    45121 ctttcccgcg cccgtgaata tgtgctggaa aacatgtccg aaccggtgac ggtgctggac
    45181 ttgtgtaatc aactgcatgt cagccgccgc acgctacaaa acgcatttca cgccattttg
    45241 ggcattggtc cgaacgcgtg gctgaaacgt attcgcctga acgccgtgcg ccgcgaactc
    45301 ataagtccgt ggtcacaaag cacaacggta aaagacgccg ccatgcagtg gggattctgg
    45361 catcttgggc aatttgccac ggattatcag caactgtttg ccgagaagcc gtcactgacg
    45421 ctgcatcagc ggatgcgaga gtgggggtga gggagttaca cccaatctct gaccttaata
    45481 aactcactta aagccgcttc cgggctgccg tcttttggct gataatcata ctcccagcgt
    45541 accagtggcg gcattgacat caggatcgac tcggtgcgcc cgccagtttg caggccaaac
    45601 agcgtgccgc gatcccagac cagattgaac tcgacataac gaccgcgacg gtagagctga
    45661 aaattgcgct cgcgctcgcc gtaggccatc gctttccgtc gctctacaat tggtaaataa
    45721 gcgtcggtgt agcctttgcc taccgcctgc ataaaggcaa aacagtggtc gaaatctggc
    45781 gtgttcagat catcaaagaa cagcccgcca atgccgcgct gttcgttgcg atgtttgagg
    45841 tagaagtatt cgtcgcacca ttttttgtaa cgcggataaa cgtcttcgcc aaatggcagg
    45901 cacaggtcac gggcggtgcg gtgccagtga atggcgtctt cttcaaaacc atagaaaggg
    45961 gttaaatcga agccgccgcc aaaccaccag acgggctctg cacccggttt ttcggcaata
    46021 aaaaagcgca cattcgcgtg gctggtggga acatacggat tatgcggatg cactaccagt
    46081 gaaacgccca tcgcctcgaa actgcgcccg gcaagttccg gacgatgagc ggtggcggaa
    46141 gcaggcatcg cctcaccgtg aacatgtgaa aagttgacgc ccgcttgttc gaaaacacca
    46201 ccattacgca acacccgact acgcccaccg ccgccagctt cacgttgcca gctatcttcg
    46261 acaaactctg cgccatcgac ggcggtcagt tgttgacaaa ttgtatcctg aaggttgagc
    46321 aagaactgtt taaccaggtg tgcgtcgggt ttcatcactt accgctttct cgagtgtgct
    46381 ttctggttgt caaaccagtg gaaataactg atcacgcctt cggcaatcgc tgtggcgatt
    46441 ttctggcgaa acgccgccgt gcctaacagc cgctcttctt ccgggttggt gataaacgag
    46501 gtttccacca gcaccgacgg aaccgacggc gatttcaaca ccacaaacgc ggcttgttcg
    46561 gtgttgcggc tgtgcagttt atgcaccggc ttaatctttt tcagaatatg cgagccgagc
    46621 gtcaggctgt ttttaatagt atcggtttgc accagatcaa acagcacttg ctgcaatagg
    46681 tgatccttgt cagtcgcttt tttaccggca acttcatcgg cgcggttttc gcgttcagac
    46741 aggtattttg ccattgcgct acttgccccg cggttagaga gggcaaatac cgaagcaccg
    46801 gcagctttcg ggttggtaaa gccgtcggca tgaattgaca taaacagatc tgcgccatgt
    46861 ttatgggcga tttcaacgcg atcgtacagt gggataaacg tatcgccaga acgcgttaaa
    46921 cgcgcatcaa tgccatgatt acgcaatatg gaacggacat tcttggcaat tgccagcacc
    46981 acatgttttt ctttcgaacc gttgcgtccg atcgctccgg tatcaatccc gccgtggcct
    47041 ggatcgagaa caacgacacg tctgccgccg cttttttttg ctttcggctt gctgtgtccg
    47101 ttactggttt ttaacggttc ttctttggcg atggcttgcg acattcctga caacgtcagg
    47161 gcagccaaac cggctttcag cacctggcgg cgcgaagtga gtgtttttag tggtttaaaa
    47221 gtgctcatac ggcctgagtt gtaataataa agttccagat gttatatcgt atcgcgtaat
    47281 ccgttacgac ggtttgctgt tgagaattgt tttacttttc atttcaatag ttgacaactc
    47341 cccattatgc cactttttca accgattttc gtcagatatt ggctaattcg accgttcacg
    47401 ccataatcag ccttttaacc cgcaaaaagg taacgaatac catggagata cgcgtatttc
    47461 gccaggaaga tttcgaagag gtcatcaccc tttgggagcg ttgcgacttg ctgagtccgt
    47521 ggaacgatcc ggaaatggac atcgagcgta agatgaacca tgacgtcagt ttgtttctgg
    47581 tcgctgaggt gaacggtgaa gtggtcggaa cggtgatggg cggttatgac gggcatcgcg
    47641 ggtctgctta ttatcttggc gtgcatcccg agtttcgtgg gcgtgggatt gctaatgcgt
    47701 tgcttaatcg gctggagaaa aagctgattg ctcgcggctg tccgaaaatt cagatcaacg
    47761 tgccggaaga taacgacatg gtgctcggaa tgtatgaacg cctgggatat gaacacgccg
    47821 acgtgctgag tctgggtaag cgtttgattg aagatgaaga gtactgagtt tcatcctgtc
    47881 cattatgatg cgcacggtcg cctgcgttta cccttgctct tctggcttgt gctattgctt
    47941 caggcgcgaa cctgggtgct gtttgtcatt gccggagcgt cgcgcgagca gggtactgcg
    48001 ctgctaaatc tgttttatcc cgatcacgat aatttctggc tggggttgat tcccggtatt
    48061 ccggcggtgc tggcattttt gctgagtggt cggcgggctt catttccccg tatctggcat
    48121 gtgctctatt ttctgttgct gttggcgcaa gtggttttac tttgttggca accgtggctg
    48181 tggctgaacg gtgaatccgt tagcggtatc ggtctggcgc tggtagtggc ggatatcgtg
    48241 gcgttaatct ggctgctgac caatcgacgt ttacgcgctt gttttaatga agaaaaagaa
    48301 taacggcact ttttggtgaa tttgcactcc aagcaacgtt attgaataac caaaggaagt
    48361 gacatgaaat cgctgcgttt aatgttatgc gctatgccgt tgatgctgac cggctgttcc
    48421 acgatgtcgt cagttaactg gtcggccgct aacccgtgga actggtttgg atcatccacc
    48481 aaagtgagcg agcagggcgt gggtgaatta acggcgtcca caccactgca agaacaagcc
    48541 attgctgatg cgcttgatgg cgattatcgc ctgcgcagcg gaatgaaaac cgcgaacggc
    48601 aacgtggtgc gcttttttga agtgatgaaa ggcaacaacg tggcgatggt gattaacggc
    48661 gatcaaggca cgatcagccg cattgatgtg ctggatagcg atattcctgc tgacaccggt
    48721 gttaaaatcg gtacaccgtt tagtgacctt tacagcaaag catttggcaa ttgccaaaag
    48781 gccgacagtg atgataatcg tgccgtcgaa tgtaaagccg aaggcagtca acatattagc
    48841 taccagttca gcggggaatg gagtggtcct gaagggttaa tgccttcgga cgataccctg
    48901 aaaaactgga aagtcagtaa aattatctgg cggcgttaat ttgcgtctga acaaaccgcc
    48961 gccgcgaaaa aacacgtaaa atagcgccca acaatgccac ggattgcgtg gcattattat
    49021 tttcaggagg aacaatgtct caggttcaga gtggcatttt gccagaacat tgccgcgcgg
    49081 cgatttggat cgaagccaac gtgaaagggg aagttgacgc cctgcgtgcg gccagtaaaa
    49141 catttgccga caaactggca acttttgaag cgaaattccc ggacgcgcat cttggtgcgg
    49201 tggttgcctt tggtaacaat acctggcgcg ctctgagcgg cggcgttggg gccgaagagc
    49261 tgaaagattt tccgggctac ggtaaaggtc ttgcaccgac gacccagttc gatgtgttga
    49321 tccacattct ttctctgcgt cacgacgtga acttctctgt cgctcaggcg gcgatggaag
    49381 cctttggtga ctgcattgaa gtgaaagaag agatccatgg cttccgttgg gttgaagagc
    49441 gtgacctgag cggctttgtt gacggtacag aaaacccggc gggtgaagag acgcgccgcg
    49501 aagtggctgt tatcaaagac ggcgtggatg cgggcggcag ctatgtgttt gtgcagcgtt
    49561 gggagcacaa cctgaagcag ctcaatcgga tgagcgttca cgatcaagag atgatgattg
    49621 ggcgcaccaa agaggccaac gaagagattg acggcgacga acgtccggaa acctctcacc
    49681 tgacccgcgt tgatctgaaa gaagatggca aagggctgaa gattgttcgt cagagcctgc
    49741 cgtacggcac cgccagtggc actcacggtc tgtacttctg cgcctactgc gcgcgtctgc
    49801 ataacattga gcagcaactg ctgagcatgt ttggcgatac cgatggtaag cgtgatgcga
    49861 tgttgcgttt caccaaaccg gtcactggcg gctattactt cgcaccgtcg ctggacaagc
    49921 tgatggcgct gtaagcgttt ctgattcatt gattaaaggc cagccagtaa cacaactgac
    49981 tggccttttt attactgctt tgacgccgca tacacttgat caactacttt ctgccaaaac
    50041 agggtatttt gcggcgctga cgctacagct aatagccagc agagaaagat agagcattgt
    50101 ccgtttcata atcagtccag attgacgtta cggcagccaa agagtgtggt gaaaataaac
    50161 ccactaaccc atgccaccag aataccgcca gcgtaaaccg ccattgccgg aaggatgcct
    50221 tgtgcggaag tcatcagcgg cagcgccacc agaccagacg gcccgaaggc gctgtttaag
    50281 cccatcggca gaccccacca ggctatcagg ccgataaaca aaccgcccgc cgcgccgcct
    50341 aaacaggcgg taacaaacgg tttcatgcgg ggcagggtga caccgtaaat cagcggttcg
    50401 ccaacgccaa gcagaccggg aataatcgcc ccgcggacct gactgcgtaa tgcactgtgc
    50461 ggttgcgccc gccagtagag cgccagcgcc gcgcccacct ggcctgcgcc tgccattgaa
    50521 aggatgggaa ataagctgtt gaatccctgg ctgtccatta acgccagata aacaggaata
    50581 aagccctgat gcacgccaaa taccacggcg atcaggaaca gcccggctaa aaccgcacaa
    50641 ccgagcggat tactgttcag gtgcataaac agccatgaca taccttcaaa cagccagccg
    50701 cccagcggca taatgatcag gtacgcaagc gtagcggtga tcagcagggt gattaatgag
    50761 gtcaacagca tgtcgaggtc gtccggcata aagcggcgca ccatgcattc gatgcgggcg
    50821 caggcccatg cggcaatcaa cacgccgata atattgccgc gcggatcgat aggcagacca
    50881 aagaaatcgt gaaatccggc gtagtaaccc gtggttgcag cggggttata accgagcaaa
    50941 aagagcgcag cgataattgc gccatttacg cccgtgccac caaatgcctg ggccgcgtta
    51001 tagcccacca gaattaccag gaaggtgaac aggcctttgc tgaacacctt cataaaattc
    51061 agcgcatcgg gtagcgtgcc ctgagcatct gccggaacgt gcatcaccgt ggcaattaac
    51121 gtcgctatcc ccagcagcag accggcggca ataaaaccgg ggatcagcgg cgtgaagatg
    51181 gtggcgaatt tggcgagaaa ttgttgcacg ccggaagttt gtctggcttt taactggcgt
    51241 ttattctggg cggcgatttc tgcggcatcc tgtaccggtg cctcgcccag cagctcgctc
    51301 atggcttttg cggcacgatg cgctttgcct ggcccaaaaa ccacctgcac ctgatcgctg
    51361 gtcaaaatga cccccttcac gccttccagc gttttgatat tgggatcaac cagtgaactg
    51421 tcatgtacac ccagacgcag gcgcgtcata cagttaccac aactggcgat atttcccggt
    51481 ccgccgaccc gggtaagaat ggtgtttaga agttcactgc tgatctcttt agccatgggt
    51541 tattcctttt ccagagcctt gcgaataaaa ccgccgtgtt gatccaggca ttttttagct
    51601 tcagcggcat cgagattttt cagtaccatc actatggccg ttttacagtt gcgctcgcaa
    51661 gcaattaacg ccgcttccgc ttgttcggca ttacatccgg tagcgttttt gacgatattg
    51721 acctggcgca catgcagttt ttcgttggtg gcgaccacat cgaccatcag gttgccgaac
    51781 actttgccgg atttaatcat cagcccggta gagagcatgt tgagcaccag tttctgcgcc
    51841 gtgcctgctt tcattcgcga agaaccggta acaacttcgg caccaactac cggcgtaata
    51901 gcaaactctg cggtggatga aacggcactc cccggattac aggaaatgcc cactgtacgg
    51961 cagccgagtt ggcgcgcgta ttccagcccg gcaatcacat acggcgtgcg tccgctggcc
    52021 gcaataccaa ccaccacatc ctgcgcggtt aagccgatat ttttcagatc attaacacca
    52081 ccttcccggc tatcttctgc gccttccacc gcgtgctgaa tggcatattc gccgccagca
    52141 atcaaaccaa ctaccaggcc cggtttcacg ccgtaggtcg gcggacattc gctggcatcc
    52201 agaatcccca gacgaccgga tgttcccgca ccgagataaa tcagacggcc gccgccgctt
    52261 acctgggtgt ggataacatc gatcgccgcg gcgatatccg gcagtacgcg ctcaacggcg
    52321 agtggtacgg ttttatcttc atcgttgata atccggcaca tttccagcgt tgatacgcgg
    52381 tcaatttcag ccgaggcggc gttcgagcct tcggtaatca tcttttcaag ttgcatcggt
    52441 ggtgacctta atatttgcga tcaaataatt gcagataaat gggatcatat atcccgattt
    52501 gatagacaca aaggaatcat taagtccgaa tattactcat gtgatgtcac tgaaaatgat
    52561 tgcgcgctga cgtaacgctt gaggtgctgc ataaagcagc gactaaattg agattttcct
    52621 gaattagtga gctgatccgc agcaatattt tgtttatcct gtattttcag agggaatgga
    52681 gtgtaacgct ctgtattaac aaggagagca ttaaaatggg taaactcacg ggcaagacag
    52741 cactgattac gggcgcattg cagggaattg gcgaaggaat tgccagaact tttgcacgtc
    52801 atggcgcaaa cctaatcttg ctggatatct cccctgagat cgaaaagctg gcggacgaac
    52861 tgtgtggtcg tggtcatcgc tgtacggcgg ttgtcgccga tgtgcgtgac ccggcgtcgg
    52921 tagccgcagc tattaagcgc gctaaggaaa aagaaggacg cattgatatt ctggtgaata
    52981 acgcaggcgt ttgtcgtctg ggcagcttcc tcgatatgag cgatgaagat cgcgatttcc
    53041 atattgatat caatataaaa ggcgtatgga acgtcacgaa ggcggtgctg ccggagatga
    53101 ttgcccgcaa agatggccgc attgtgatga tgtcttcagt cactggcgat atggtggcag
    53161 acccgggcga aacggcgtac gccttaacga aagcggcgat tgttggcctg actaaatcgc
    53221 tggcggtgga gtacgcgcag tctggtattc gcgttaacgc catctgccct ggatacgttc
    53281 gcacgccaat ggcggaaagc attgcccgcc agtcgaaccc ggaagatcca gaatcggtgc
    53341 tgactgaaat ggcgaaagca atcccgatgc gtcgcctcgc cgatccgctg gaagtcggcg
    53401 aactggcggc cttcctcgca tcggatgaat ccagctattt aacaggtaca cagaatgtga
    53461 ttgatggcgg cagcacactg ccggagacgg ttagcgtcgg catctgattc acctctgttt
    53521 cctccctgca tttgtgggga ggatttcgtc ttattccctt ttcaacttcc aaatcaccaa
    53581 acggtatata aaaccgttac tcctttcacg tccgttataa atatgatggc tattagaaag
    53641 tcattaaatt tataagggtg cgcaatggcc gttaacttac tgaaaaagaa ctcactcgtg
    53701 ctggtcgctt ctctgctgct ggcgggccat gtacaggcaa cggaactgct gaacagttct
    53761 tatgacgtct cgcgcgagct gtttgccgcc ctgaacccgc cgtttgaaca gcaatgggcc
    53821 aaagataacg gcggcgacaa actgacgata aaacaatctc atgccgggtc atcaaaacag
    53881 gcgctggcga ttttgcaggg cttaaaagcc gacgttgtca cttataacca ggtgacagac
    53941 gtgcagatcc tgcacgacaa aggcaagctt attccggctg actggcagtc gcgtctgcca
    54001 aacaacagct cgccgttcta ctccaccatg ggcttcctgg tgcgtaaggg taacccgaag
    54061 aatatccacg actggaacga tctggtgcgc tccgacgtga agctgatttt tccgaacccg
    54121 aaaacctccg gtaacgcgcg ttacacctat ttagccgcgt ggggtgcagc ggataaagcc
    54181 gacggtggcg ataaagccaa aaccgaacag tttatgaccc agttcctgaa aaacgttgaa
    54241 gtgttcgata ctggcggtcg tggcgcgacc accacttttg ccgagcgcgg cctgggcgat
    54301 gtgctgatca gcttcgagtc ggaagtgaac aacatccgta aacagtatga agcgcagggc
    54361 tttgaagtgg tgattccgaa aaccaacatt ctggcggaat tcccggtggc gtgggtggat
    54421 aaaaacgtac aggccaacgg cacggaaaaa gcggcaaaag cctacctgaa ctggctctac
    54481 agcccgcagg cgcaaaccat catcaccgac tattactacc gcgtaaataa cccggaagtc
    54541 atgggcaaac tgaaagataa attcccgcag accgagctgt tccgcgtgga agataaattt
    54601 ggctcctggc cggaagtgat gaaaacccac ttcaccagcg gcggcgagtt agacaagctg
    54661 ttagcggcgg ggcgtaagta atgtttgcag tttcttcaag acgcgtgctg ccgggcttta
    54721 ccttaagcct cggcaccagt ctgctgtttg tgtgcctgat tttgctgctg ccgctctccg
    54781 cgctggtgat gcaactggcc cagatgagct gggcgcagta ctgggaggtg atcaccaacc
    54841 cgcaggtggt cgcagcctat aaagtgacgc tgctgtcggc gtttgtggca tcgattttta
    54901 acggcgtttt cggtctgctg atggcgtgga tcttaacccg ctatcgcttt ccgggtcgca
    54961 cgctgcttga tgcgctgatg gatttaccct ttgcgctgcc aacggcagtc gccggtttaa
    55021 cgctggcctc gctcttttcc gtgaacggtt tttacggtga atggctggcg aagtttgata
    55081 tcaaagtcac ctatacctgg ctggggattg cggtggcgat ggcctttacc agcattccgt
    55141 ttgtggtgcg caccgtgcag ccggtgctgg aagagttagg cccggaatat gaagaggcgg
    55201 cagaaacgct cggcgcaaca cgctggcaga gttttcgcaa agtggtgctg ccggaactat
    55261 ctccggcact ggtggcgggt gtggcgctgt cgtttacccg cagcctcggt gagtttggcg
    55321 cggtgatttt tatcgccggg aatatcgcct ggaaaacaga agtgacgtcg ctgatgatct
    55381 ttgttcgctt acaggagttt gattacccgg cggcgagcgc gattgcctcg gtgatcctcg
    55441 cggcatcgct gctgttgctg ttctcaatta acactctgca aagtcgcttt ggtcggcgtg
    55501 tggtaggtca ttaatggcgg aagtgacaca attgaagcgt tatgacgcgc gcccgattaa
    55561 ctggggcaaa tggtttctga ttggcatcgg gatgctggta tcggcgttca tcctgctggt
    55621 gccgatgatt tatatcttcg tacaggcgtt cagcaaagga ctgatgccgg tgttacaaaa
    55681 tctggccgat ccggacatgc tgcacgccat ctggctgacg gtgatgatcg cgctgattgc
    55741 cgtaccggta aacctggtgt tcggcattct gctggcctgg ctggtgacgc gctttaactt
    55801 ccccggacgc cagctattgc tgacgctgct ggacattccg tttgccgtgt cgccggtggt
    55861 tgctggtctg gtgtatctgc tgttctacgg ctctaacggc ccgctgggcg gctggctgga
    55921 tgaacataat ctgcaaatta tgttctcctg gccgggtatg gtgctggtca ccatcttcgt
    55981 gacgtgtccg tttgtggtgc gcgaactggt accggtaatg ttaagtcagg gcagccagga
    56041 agacgaagcg gcgattttac ttggcgcgtc cggctggcag atgttccgtc gcgtcacgct
    56101 gccgaacatc cgctgggcgc tgctttacgg cgtggtgctg accaacgccc gcgcgattgg
    56161 cgagtttggc gcggtatcgg tggtttccgg ctcgattcgt ggcgaaaccc tgtcgctgcc
    56221 gttacagatt gaattgctgg agcaggacta caacaccgtc ggctccttta ccgccgccgc
    56281 gttgttgacg ctgatggcga ttatcaccct gtttttaaag agtatgttgc agtggcgcct
    56341 ggaaaatcag gaaaaacgcg cgcagcagga ggaacatcat gagcattgag attgccaata
    56401 ttaagaagtc ttttggtcgc acccaggtgc tgaacgatat ctcactggat attccttctg
    56461 gtcagatggt cgcgttgctt gggccgtccg gttccggaaa aactacgctg ctgcgcatta
    56521 tcgccgggct ggagcatcaa accagtgggc atattcgctt tcacggtacc gacgtgagcc
    56581 gtctgcacgc gcgggaccgt aaagtcggtt tcgtgttcca gcattacgcg ctgtttcgcc
    56641 atatgacggt gtttgacaat atcgcttttg gcctgacggt gttgccacgg cgtgaacgcc
    56701 cgaatgcggc ggcgatcaaa gcgaaagtga caaaattgct ggagatggtg cagcttgctc
    56761 atctggcgga tcgttatccg gcgcagcttt ccggcggtca gaaacagcgt gtggcgcttg
    56821 cacgcgcgct ggctgtggaa ccgcaaattt tgctgcttga tgaaccgttt ggcgcgctgg
    56881 atgcgcaggt gcgtaaagag ctgcgtcgct ggctgcgtca actgcatgaa gaactgaaat
    56941 tcaccagcgt gttcgtgacc cacgaccagg aagaggcgac cgaagtagct gatcgtgtag
    57001 tggtgatgag tcagggcaat attgaacaag ctgacgcacc ggatcaggta tggcgtgaac
    57061 cggcgactcg ttttgtgctg gagtttatgg gcgaggtaaa ccgcctgcag ggaaccattc
    57121 gcggcgggca gttccacgtt ggcgcacatc gctggccgct gggatacacc cccgcgtatc
    57181 aggggccggt ggatctcttc ctgcgcccgt gggaagtgga tatcagccgc cgtaccagcc
    57241 tcgattcgcc gctacccgta caggtactgg aagccagccc gaaaggtcac tacacccaat
    57301 tagtggtgca gccgctgggg tggtacaacg aaccgctgac ggtcgtgatg catggcgacg
    57361 atgccccgca gcgtggcgat cgtttatacg ttggtctgca acatgcgcgg ctgtataacg
    57421 gcgatgagcg tattgaaacc cgcgatgagg aacttgctct cgcacaaagc gcctgatagg
    57481 ttgagtgaat gttaaacgcc cggaggcgct tcccgcgatc cgggtttttt aatggcaagg
    57541 ttttgtaacc tgtaggtctg ataagacgcg taagcgtcgc atcaggcaac accacgtatg
    57601 gacagagatc gtgagtacat tagaacaaac aataggcaat acgcctctgg tgaagttgca
    57661 gcgaatggcg ccggataacg gcagtgaagt gtggttaaaa ctggaaggca ataacccggc
    57721 gggatcggta aaagaccgtg cggcgctttc gatgattgtc gaggcggaaa agcgcggcga
    57781 gattaaaccg ggtgatgtgc tgatcgaagc caccagtggt aacaccggca ttgcgctggc
    57841 aatgattgcg gcgcttaaag gctatcgcat gaaattgctg atgcccgaca acatgagcca
    57901 ggaacgccgt gcggcgatgc gtgcctacgg tgcagaactg attctggtca ccaaagaaca
    57961 gggcatggaa ggcgcacgcg atctggcgct ggagatggcg aatcgcggcg aaggaaagtt
    58021 gctcgatcag ttcaataatc ccgataaccc ttacgcccat tacaccacta ccgggccgga
    58081 aatctggcag caaactggcg ggcgtattac ccattttgtc tccagcatgg gaacaaccgg
    58141 cactatcacc ggcgtgtcac gctttatgcg cgaacaatcc aaaccggtga ccattgttgg
    58201 cctgcagccg gaagaaggca gcagtattcc cggcattcgc cgctggcctg cggaatatct
    58261 gccggggatt ttcaatgctt ctctggtgga tgaggtgctg gatattcatc agcgcgatgc
    58321 ggaaaacacc atgcgcgaac tggcagtgcg ggaagggatt ttctgcggcg taagctccgg
    58381 cggcgcggtt gccggagcac tgcgggtggc aaaagctaac cctggcgcgg tggtggtggc
    58441 gatcatctgc gatcgtggcg atcgctacct ttctaccggg gtgtttgggg aagagcattt
    58501 tagccagggg gcggggattt aagattattg cgcaggcacc gttttatccg tctgcgcaat
    58561 taacgcatgt aaaaaaggct gtgcgttctc atcgctctta ccgggcatct tcacgatata
    58621 cggcttcccg gtaatcgatg acgacgaggc caccttgtca ataaactgct cggctgtatc
    58681 aatgcgatta cgggtattgc ccagcttcag gcgcagatga gaaaccgctt catcgcaggt
    58741 atgttcatca ccgttgcgca caaatatcaa atcctttttc tgtgctaatc cctccagcat
    58801 ggcgttgata cgggcttctt catgggccgt taacttcgca taagcgggga gtgtcattag
    58861 cagcgtaacg accagacaaa tgattttctt cactgaatta ccttatcctt gttttgtaat
    58921 agccgatttg actgccagaa tcaggtaaag tttcggctgg aatacgatga ggatcatcgg
    58981 caaggagaaa aaattaaatg agtagtttgt tgttgtttaa cgataagagc agggcactgc
    59041 aggcggatat cgtcgccgtg cagtcgcagg tagtgtacgg cagcgtaggc aacagcattg
    59101 cggtgcctgc tataaagcag aacggcctga atgtctttgc cgtgccgacg gtattgctga
    59161 gcaatacgcc gcattatgac actttctacg gtggtgcgat tccggatgaa tggtttagcg
    59221 gttatttgcg tgcgcttcag gagcgtgatg cgctgcgcca acttcgtgct gtaaccacgg
    59281 gctatatggg aacggcatcg caaatcaaaa tccttgccga gtggctgact gcgctacgca
    59341 aagaccatcc tgacctattg atcatggtcg atccggtgat tggcgatatt gatagcggaa
    59401 tttatgtcaa acctgacctt cccgaggcgt atcgacaata tttactgccg ctggcacagg
    59461 gaattacccc caatatcttt gagctggaaa tcctgaccgg taaagattgc cgcgatctcg
    59521 acagtgccat tgctgccgca aaaagtctgc tttcagacac attaaagtgg gtggtgatta
    59581 ccagcgcctc cggcaatgaa gaaaatcagg agatgcaggt tgtggtggtc agtgccgaca
    59641 gcgtgaatgt catttcccat tcccgggtta aaactgacct gaaagggact ggcgacctgt
    59701 tttgtgctca gcttatcagt ggtttgctga aagggaaggc gttaaccgat gcggtgcacc
    59761 gcgcggggtt gcgcgtactg gaagtgatgc gctataccca gcagcatgag agcgatgaat
    59821 tgattttgcc gcctctggct gaagcataaa aaaatggcgc cgatgggcgc catttttcac
    59881 tgcggcaaga attacttctt gatgcggata accggggttt cacctacggt tacgctaccg
    59941 gacagtttga tcagttcttt gatttcgtcc atgttggaga taacaaccgg agtcagggta
    60001 gacttggctt tctcttccag cagcggcaga tcaaattcaa tgacagtatc accaactttc
    60061 acgcgctgac cttcttcagc aatacgcttg aagccttcgc ctttcagttc aacggtgtcg
    60121 ataccgaagt ggacgaacag ctcaacgccg ctatcagatt cgatagagaa cgcgtggttg
    60181 gtttcaaaga ttttaccaat ggtgccgtct acaggcgcga ccattttgtt acccgttggt
    60241 ttgatagcaa tgccatcacc aacgattttt tccgcaaaaa cgacatccgg cacgtcttcg
    60301 atattgacga tctcgccaga gagcggagca atgatctcaa tagttccggt atccttcttg
    60361 tcgtcggaaa ccagagattt cagtttatcg aacaaaccca tgatcttctc ctaagcagta
    60421 aattgggccg catctcgtgg attagcagat tgttttttct tcaatgaact tgttaaccag
    60481 cgtcattaac tcgtccgttg tcggttgagc aagagcctgc tctgctaaca ccttcgcatc
    60541 ttcgaagttc gtgttacgga taatcttctt aatgcgcggg atagaaatgg cgctcataga
    60601 gaattcgtcc agacccatcc ccagcaacag aagtgtagca cgttcatcgc cagcaagctc
    60661 accacacatg ccagtccatt tgccttcagc atgagaagca tcaataactt gcttgatcaa
    60721 gttcagcacg gacggtgaca ttggctggta aaggtgtgaa atcatatcat taccacggtc
    60781 aactgccaga gtgtactgcg ttaaatcatt ggtgccgata ctaaagaaat caacttcttt
    60841 ggctaaatga cgtgcaattg ttgcggcagc cggtgtttcc accattacgc cgatttcaat
    60901 tgactcgtca aacgctttac cttcgtcgcg cagttcctgt ttgtagattt cgatctcttt
    60961 gcgcagtgca cgcacttctt caacagagat gatcatcggg aacatgatgc gcaatttacc
    61021 gaaagcagag gcacgcagga tagcacggag ctgatcgcgc aggatctctt tacgatccat
    61081 cgcgatacgg atagcgcgcc agccgaggaa cgggttctct tctttcggga agttcatgta
    61141 tggcagctct ttgtcgccgc cgatgtccat ggtacgaacg ataaccgcct gcgagccaca
    61201 cgcttcagcc actgctttgt aagcagcaaa ctgttcttct tcagtgggca acgcgtcgcg
    61261 gtccatgaac aggaactcag tacgatacag accaacgcct tcagcgccgt tacgctctgc
    61321 accttcaacg tcacgaaccg taccaatgtt agcgcacact tctacctggt gaccgtccag
    61381 cgtaatagct ggcagatctt tcagtttagc aagctctgct ttttcagaag ccacttgctc
    61441 ctgaacagcg cgcattttat caataacttc gttggttgga ttgacgtaaa cctgattatt
    61501 tacggcatcc agaatcagat agtcgtcatt tttcacctga gaggtgacgc taccggtacc
    61561 cacgatagca ggcagttcca gagaacgcgc catgatagag gtgtgggaag tacggccacc
    61621 cgcgtcggtg atgaaaccca gcaccttctt caggttcagc tgtgcggttt cggacggcgt
    61681 caggtcagcg gcaaccagaa tgacttcatc ctgaatggcg ctcaggtcga taatcttcag
    61741 gcccaggatg ttgcgcagca ggcgcttacc gatatcacgt acgtcagccg cacgttcttt
    61801 caggtattca tcatccagct cttccagggc agaagcctga ccttcgataa cttcatgagc
    61861 agctgcgtca gctgtcatgt gcttatcttt aatcagggct atgatttcct gctccagctc
    61921 ctcatcttcg agcagcataa tatgcccttc aaagatggct tctttttctt caccgaacgt
    61981 ttcaccagct ttcgttttga tcgtttccag ctgggctgat gccttggcac gaccgctcag
    62041 aaaacgttca acttcctgat caacctggtc ggcagaaatt tttttccggt caatgataat
    62101 ttcgtcttct ttcagaagca gagctttacc gaaagcgata cccggggatg ctaaaatgcc
    62161 tgaaatcata accctacctt acttgtgact gatttttaaa agaacccggg aaattactcg
    62221 agttccgcca tcagtttaac cagatgttca accgctttct gctcgtcttc gccttctgcg
    62281 gagatagtca caacggtacc ttgagtcagg cccagagtct gcagtttaaa caggcttttc
    62341 gcgctggcgc ttttgccgtt ggaagtcaca gtaatttcag aagtgaagcc cttagcttct
    62401 tttacaaact gggcagcagg gcgggtgtgc agaccgttcg gagcggtaat ggtaacttct
    62461 tgctggaaca ttgtatttcc ccaacttata ggtttagtgt tgtggaacta aagtctagcc
    62521 tggcggttcg actttagcct gtattgttag cgccagtttt taacagacgc gacgcacgaa
    62581 gagcgtaata cagtccattg ctggcgggtg ttgaccgctg acgtttcgta cgtcattaaa
    62641 cattatgccg ctaaaggaag aattgaacca aatcataaaa tcgattcagc tttggctttt
    62701 cctgtaacga ttaatttcgc gcatcaaaat aattagtctg gttaaatacc agttccgaca
    62761 ggctgaatca atgccaggag gggcgaaagt ttgaagcagg ccacaaaaaa gcacctaaaa
    62821 aggtgctttt ttacgcattt tttacaagct ggcattactg ttgcaattct ttctcagtga
    62881 agagatcggc aaacaatgca gtgcttaaat aacgctcacc cgatgacggc agaataacca
    62941 caatattctt attggtaaag ctttcatctt cttgtagttt caacgccgca gcaacagctg
    63001 ctccagaaga gataccagca agaatgcctt cttcttccat cagacgacgt gcggtagaaa
    63061 tggcttcttc attggtgatg ccaatgactt tgtcgaccag cttgagatca aggttagccg
    63121 ggataaaacc agcgccaata ccctgaattt tatgcggacc aggtttaatc tcttcacctg
    63181 ccagcgcctg ggcgataact ggagaatcgg ttggctcaac ggcgacagag ataagatcgg
    63241 tcttgccttt ggtgccttta atgtagcggc tgacgccagt cagcgtaccg ccagtcccaa
    63301 cgccagcaat aaatacatca acctgaccgt cggtatcttc ccagatctcc ggaccggtgg
    63361 ttttttcatg aatttcaggg tttgccggat tgctgaattg ttgcagcagc aggtatttct
    63421 ctggattgct ggcgacaatt tcttctgctt tttggattgc gcctttcatg cctttagcac
    63481 cttcggtcag caccaggttt gcacctaacg ctttcagcag cttgcggcgt tcaatactca
    63541 tggtttctgg catggtcagg gtaagtttgt aaccgcgagc ggcagctaca taggccagtg
    63601 caatcccggt attaccgctg gttggttcaa ccagttcaac gcctggtttc agcacgccgc
    63661 gcttttcggc atcccaaatc atgttggcac cgatacggca cttaacgctg aagctggggt
    63721 tacgagattc caccttcgcc agaatgcgtc cgttaccgat gcgattcagg cgaaccagcg
    63781 gcgtgtgacc gatagtcagc gagttatctt caaaaatctt actcatggcc tgtccttaac
    63841 tgtatgaaat tgggatacaa caggtagcat acccgctcag agaatatgcg gaagtaagga
    63901 tttagcatat ctatatgcag aagggaaata atgacatgca agatggaata aggggcggca
    63961 taagccaccc ctgtttcaca caaacggttt acaaaataac cggtagattg ttaccgccac
    64021 atggcgtgtt tatcgcgata gcaatcaacc cacatcgccg tcgcgccaca aacggcaacg
    64081 ggcataatga acagattaag cagcgggatc atcgtaaaca ggctggttaa agcaccaaac
    64141 tgcatattgg tgattttgcg tgtgcgcagg gcggtgcgca tctctttaaa cggcactttg
    64201 tggttatcga aggggtaatc acaatactgg atggctaaca tccaggcgct aaacaggaac
    64261 cacagtaccg gcgcgacggt ttgcccaatg ccagggatga agtaaagaat tagcaataca
    64321 attgcgcgcg gcagatacca ggcaaatttt tgccattcgc gtttcatgat tcgcggcaca
    64381 tctttcatga taccgaaaat tccggtatct ggcggtgtag cgccagtcag tcttgcttcc
    64441 agttgttcag ccaataaacc gttgaacgga gcagcaatcc agttagcaat cgttgagaag
    64501 aaatagccaa acactaacag cacagagatg acagccaggg gccacaacag atagctcagc
    64561 cattgtaacc agtccggaac ataactcatg agagtcggga tccagacatc gagttgcgta
    64621 aagagccacc agaatgcgcc ccccatcaac aaaatattga ccagcagcgg taaaataacg
    64681 aaacgccgaa tcccaggttg cgagacgagc ttccagcctt gcgcaaaata gtaaaaaccg
    64741 ctgcgtgggg cagatgtgaa tgatgaaacc ataatcagga tgagctcctt ttgaccaatc
    64801 ccaggaaaat tctgcgtatt ttaccgggta attgcgcaat ggacagttag gatatgttcg
    64861 aaaaaacagc aaaaagcacg atttcatcta tctttgtgct gtgaaagtta atagtgcact
    64921 tgcacttgag gtaatcggca aatactctta gtgagtaaat gtttgccgtg gtggcaaggt
    64981 gttagaacaa cagagaatat aatgatgcag gatttgcgtc tgatattaat cattgttggc
    65041 gcgatcgcca taatcgcttt actggtacat ggtttctgga ccagccgtaa agaacgatct
    65101 tctatgttcc gcgatcggcc attaaaacga atgaagtcaa aacgtgacga cgattcttat
    65161 gacgaggatg tcgaagatga tgagggcgtt ggtgaggttc gtgttcaccg cgtgaatcat
    65221 gccccggcta acgcccagga gcatgaggtt gctcgtccgt cgccgcaaca ccagtaccaa
    65281 ccgccttatg cgtctgcgca gccgcgtcaa ccggtccagc agccgcctga agcgcaggta
    65341 ccgccgcaac atgctccgcg tccaacgcag ccggtgcagc aacccgtgca gcagcctgcc
    65401 tatcagccgc agcctgaaca gccgttgcag cagccagttt cgccacaggt cgcgtcagcg
    65461 ccgcagccag tgcattcagc accgcaaccg gcacaacagg ctttccagcc tgcagaaccc
    65521 gtagcggcac cacagcctga gcctgttgcg gaaccggctc cagttatgga taaaccgaag
    65581 cgcaaagaag cggtgattat catgaacgtc gcggcgcatc acggtagcga gttaaacggt
    65641 gaactgcttc ttaacagcat tcaacaagcg ggcttcattt ttggtgatat gaacatttac
    65701 catcgtcatc ttagcccgga tggcagcggc ccggcgttat tcagcctggc gaatatggtg
    65761 aaaccgggaa cctttgatcc tgaaatgaag gatttcacta ctccgggtgt cactatcttt
    65821 atgcaggtac cgtcttacgg tgacgagctg cagaacttca agctgatgct gcaatctgcg
    65881 cagcatattg ccgatgaagt gggtggtgta gtgcttgacg atcagcgccg tatgatgact
    65941 ccgcagaaat tgcgcgagta ccaggacatc atccgcgaag tcaaagacgc caacgcctga
    66001 tacacttaag gcaaattaac tccttttcga acccccgctt gtcgggggtt tttagcattg
    66061 atggtgcgat atggaatcaa tcgaacaaca actgacagaa ctgcgaacga cgcttcgcca
    66121 tcatgaatat ctttatcatg tgatggatgc gccggaaatt cccgacgctg aatacgacag
    66181 gctgatgcgc gaactgcgcg agctggaaac caaacatcca gaactgatta cgcctgattc
    66241 gcctacccaa cgtgtaggtg cagcgccgct ggcggctttc agccagatcc gccatgaagt
    66301 gccaatgctg tcgctggata acgtttttga tgaagaaagc tttcttgctt tcaacaaacg
    66361 tgtgcaggac cgtctgaaaa gcaacgagaa agtcacctgg tgctgtgagc tgaagctgga
    66421 tggtcttgcc gtcagtattc tgtatgaaaa tggcgtttta gtcagtgccg cgactcgtgg
    66481 cgatggcact accggggaag atatcacgtc taatgtgcgt actattcgcg ccattccgct
    66541 gaagctacac ggtgagaata tcccggcgcg tctggaagtg cgtggtgaag tgttcctgcc
    66601 gcaggcgggg ttcgaaaaga ttaacgaaga tgcgcgacgc acgggcggga aagtgtttgc
    66661 taacccacgt aatgcggcag ctggttcact gcgtcagctt gatccgcgta ttacagcgaa
    66721 gcgaccgctc actttcttct gctacggcgt tggtgttctg gaaggcggtg aattgccgga
    66781 tacccatttg ggacgcttaa tgcaatttaa agcatgggga ttacctgtca gtgatcgggt
    66841 aacactttgt gaatcggcgg aagaagtgct ggcgttttat cacaaagtag aaaaagaccg
    66901 tccgacgctg ggctttgata tcgacggcgt ggtgattaag gtcaactcac tggcacagca
    66961 ggagcagctt ggctttgtcg cgcgtgcccc gcgctgggcg gtagcgttta aattcccggc
    67021 gcaggaacag atgacctttg tgcgtgacgt cgagtttcag gttgggcgta ctggcgcgat
    67081 tacgcctgtt gcgcgtctgg aacctgtcca tgttgctggc gtgttggtga gtaacgctac
    67141 actgcataat gctgacgaaa tcgaacgtct tggtttacgc attggcgata aagtggttat
    67201 tcgccgcgct ggcgacgtga tcccgcaggt ggttaacgtc gtgctttctg aacgcccgga
    67261 agatacccgt gaggttgtat tcccgacgca ttgtccggta tgtggttctg acgtcgagcg
    67321 tgtggaaggt gaagcggttg cccgctgtac cggtggcctg atttgcggtg cgcagcgtaa
    67381 agagtctctg aaacactttg tttcccgccg tgcgatggat gttgacggaa tgggcgacaa
    67441 aatcatcgat caactggttg aaaaagaata tgtccacact ccggcggatc tgttcaaact
    67501 caccgcaggc aaactgaccg gactggagcg tatggggccg aaatcggcac aaaacgtggt
    67561 taacgcgctg gaaaaagcga aagaaaccac ctttgcccgc ttcctctatg cacttggcat
    67621 ccgtgaagtc ggcgaggcta ccgcagcagg tctggcggca tatttcggca cgctggaagc
    67681 gctggaagcc gcgtcgattg aagagctgca aaaggtgcct gatgttggaa ttgtcgttgc
    67741 ctcccacgtt cacaacttct ttgccgaaga aagcaaccgc aatgtcatca gcgagctgtt
    67801 ggcggaaggt gttcactggc ctgagccgat cgttatcaat gcggaagaga ttgacagtcc
    67861 gtttgctggt aaaaccgtgg tgcttacggg cagcttaagc cagatgtcgc gtgatgacgc
    67921 taaagctcga ctggtcgaac tgggggcgaa agtcgcgggc agcgtgtcga agaaaaccga
    67981 tctggtgata gcgggtgaag ctgcaggatc taaactggcg aaggcgcagg aactgggtat
    68041 tgaagtcatc gacgaaacgg aaatgctgcg tttgctgggt agctgagatg gaaaaagagc
    68101 agctgattga aatagccaat acgataatgc cgtttggcaa gtacaaaggg cgtcgcttaa
    68161 tcgacctgcc ggaggagtat ctgctgtggt ttgcccgcaa agatgagttc ccggcaggga
    68221 agctcggtga gctaatgcaa atcacgctgc tgattaaaat cgaggggctg acgcaactgg
    68281 tccagcccct gaaacgtccg ctttaagctt tatcggcgct gctttcctgc tgcgcctgta
    68341 actgttcggt ctggcgtttg tatcgacgcg ccagcaccgc acagaccatc aattggatct
    68401 gatggaaaat catcaggggc agcaccatca taccgatcac cgatgtgggg aacagaatgt
    68461 ttgccatcgg gatgccattt gccagactct ttttcgaacc acaaaagacg atagtaattt
    68521 catctgcctt attgaagccc agtcggcgtg ccataaagac gttaactaca atcacgatag
    68581 ccagaagaac gcaactgacc accacgataa acagcaatga tccccagcca actttgtgcc
    68641 agataccgtt aacgacggct tcgctgaatg ccgtataaac taccaacaga atggacgtct
    68701 ggtcagtttt cgcaatccat tttttattac gcgacaccca gtcaccaatc cacggccggg
    68761 aaagatgccc caacacaaat ggcagcaaca gttgcagcat aattttaccg acctgctcaa
    68821 ggctgccccc tgcaccgtga acattcatca ccagaccaac cagcaatggt gaaaggaaaa
    68881 tccccagcag gctggatgct gacgcagaac aaaccgccgc cgcgacgtta ccgcccgcca
    68941 ttgacgtgaa ggcgattgca gactgcacgg tcgcggggag aatgcacaag tagagaaaac
    69001 cggagtagag catcgggtcg acatttaccg gtttccacca ggcaaacagc acgcccagaa
    69061 tcggaaacag cacgaaggtg ctgcacatta cccacaaatg cagtcgccag tggccaccgc
    69121 cagcaataat cgcctcacgc gataacttcg cgccgtgcat aaaaaacagc agggctatcg
    69181 ctgcggtggt cagattttca aagaagggga cgaaatcgcc tctggccgga aagaaagagg
    69241 ccagcaacac caccgtgatc agggttaagg tgaaaggatc gaggatacga aaaagtttca
    69301 taaagactcc agatgatcga tggttctatt gtgcgtcttc cagtttgaga aataaaattg
    69361 atttattgca tccattcatg aaaaaaacag atgaattatt ctttaaagca attaaaggtt
    69421 ttcgtcacag tagcgcagga gaaaagtttt agtcgtgcag gagagcgtat cggcctgagc
    69481 cagtcggcag tgagtcacag tgtgaaggag ctggaaaatc atactggtgt tcgcctgctg
    69541 gacagaacca cgcgtgaagt ggtgcttaca gatgcagggc agcagttggc tttgcgtctt
    69601 gagcgactgc tggatgaact taacagcacg ttgcgcgata ccgggcgtat ggggcaacaa
    69661 ctgagcggaa aagttcgggt cgctgccagc cagaccattt ccgcgcatct tattccgcaa
    69721 tgcattgctg aaagccatcg ccgctatcca gatattcagt ttgtcctgca cgatcgtccg
    69781 cagcagtggg tgatggaaag tattcgccag ggagatgtcg attttggcat cgtcatcgat
    69841 cctggcccag tgggcgatct gcaatgtgaa gcgattcttt ccgagccttt ctttctgctt
    69901 tgccatcgcg atagcgcttt ggccgtggaa gattatgtcc cctggcaggc attacaggga
    69961 gcgaaattgg tgttgcagga ttacgcgtca ggcagccgac cgctgattga cgcagcgctg
    70021 gcgcgcaacg gtattcaggc gaatattgtg caggagattg gacatccggc gacgctgttc
    70081 ccgatggtag ccgcaggcat cggcatcagt attcttcccg cactggcgct accattgcct
    70141 gaaggtagcc cactggtggt aaagcgcatt acgccagtgg ttgaacgcca gttgatgctg
    70201 gtgcgcagga agaaccgttc actttccacc gccgctgaag cgttatggga cgtagtacga
    70261 gaccagggca atgcgctaat ggctgggcgg gaaggggatc cgttgtatca gatatagagt
    70321 gaattcatac tgccgggagc tccggcagta atcaatcaga aattaaattt gatggagtag
    70381 attatcgcat cctggtaaaa atcttcgccc agtttgtcat ccgcataacg atactgaatc
    70441 cctgtggtga tgtgtgaagt tgcattccac caaagtgcga cggcaccgtt cagaccttct
    70501 ttgccgccat tacctgccgc gtaggtggca tcacgatcaa actcgtactc gttccagttg
    70561 gtgagggtga atttctcact gcccagcata aagctgtaac ctgcaaccca accggcgaca
    70621 taaccgttat cgccggtata ataggtttgg tctgtatagc gttttgcaaa gaacggtttg
    70681 aaccaccaac cgctgccggt gaaattgtag ccgatcccgt aaaggaacat atcgtcatgg
    70741 aaatttacac gattcgcaga accgtaggtg ccatacgcat gcaagtagag attaaatccg
    70801 gtgtcaccca ggtaaatacg gttggtattt ttaaatgtat aacgctgctc gctacccggt
    70861 ttatcatgac gatcattata aaagttttcc cagtcgaaga acccgtacat ttctccccaa
    70921 ctaaagttag cgccgccttc cagttccaga tatccaaaat catctttgtg tgatttggtc
    70981 gacgatttct cagtggttct gctagtccag tcaagataat gaatacctat atcagcaaaa
    71041 ccgcctttaa attctgcatg ggatactgct ggtatcgcca atacagaaga gagtgtcaga
    71101 gtaaaaagat gttttttcat agcataattc cctatgccga tcgttattag ttgattgctt
    71161 aataaaaagg ttgattaaaa gcggcatatt gttaatgcaa gggaaaggag agtaccaata
    71221 cagttttttc agcctattaa tagtgaaaaa atataaatat atcgatatcg aataactatc
    71281 ggatacatga aaaaagtgta ttggtatgag gtagggcaat ctcgttataa aaaggcgtta
    71341 gattcccccc tacaaaaaaa ggatatatat gtatcaggct cagttttctc ataacccact
    71401 gtattgcgta gatattatca agacttataa acctgatttc acgccacgag tggcctttat
    71461 tttaggttcc gggctgggcg cgctggccga tcagattgag aacgcggtcg caatttccta
    71521 cgaaaagctg cctgggttcc cggtaagtac cgtacacggt catgcgggtg agctggtgct
    71581 ggggtatctc cagggggtgc cagtggtgtg catgaaaggt cgcggacatt tctacgaagg
    71641 tcgtgggatg accatcatga cggatgcaat ccgtaccttt aagttgctgg gctgcgagtt
    71701 gctgttctgc accaatgcgg ctggctcact gcgccctgaa gtgggggccg gcagtctggt
    71761 cgcattgaaa gatcacatca acaccatgcc gggaacgccg atggtgggtc ttaatgatga
    71821 acgttttggt gagcgcttct tctcgctggc gaatgcctac gatgcggaat accgcgcact
    71881 gttacaaaaa gtggcgaaag aagagggggt ccctctgacg gagggcgtgt tcgtctcgta
    71941 tccggggccg aatttcgaga ctgcggcgga aattcgcatg atgcaaatta ttggtgggga
    72001 tgttgttggt atgtctgtgg tgcctgaggt tatttcagct cgccattgcg aacttaaagt
    72061 cgttgcggtc tctgcgatta ccaacatggc ggaaggtctg agtgacgtga agctttctca
    72121 tgcccaaacg ctggcagcag cggaactctc aaagcaaaac tttattaatc ttatttgcgg
    72181 ctttctgcgc aaaattgcct gagtaaaaca acaataaacg gccttactga gtgaggccat
    72241 atgatgcgac aaggaaacga ttatgagcat cgctttgcgc ttaaaggtaa tgtccttttt
    72301 gcaatatttt atctggggga gctggctggt taccctcggt tcttacatga ttaataccct
    72361 tcatttcacc ggcgctaatg ttggcatggt ttacagttcc aaagggatcg ccgcgattat
    72421 tatgcctggt ataatgggga tcatcgcaga caaatggctg cgtgcagaac gtgcatacat
    72481 gctgtgtcac ctggtgtgtg cgggcgtact tttttatgcg gcatccgtaa ctgatccgga
    72541 tatgatgttt tgggtgatgt tagtcaatgc gatggcgttt atgccgacta ttgcgttatc
    72601 gaacagcgtc tcttattcct gtcttgccca ggcagggctt gacccggtga ccgctttccc
    72661 gcccattcgc gtttttggta cggtggggtt cattgtcgcc atgtgggcag taagcttgct
    72721 gcatctggaa ttgagtagtc tgcaactgta tatcgcgtcc ggtgcgtcat tgctgctgtc
    72781 ggcttatgcg ctgactttgc cgaagattcc ggttgcggag aaaaaagcga ctacatcgct
    72841 tgccagcaag ctgggtctgg atgccttcgt gctgtttaaa aatccacgca tggctatctt
    72901 tttcctcttc gccatgatgc tgggtgcggt gctgcaaatt accaacgttt ttggcaaccc
    72961 gttcctgcat gatttcgccc gtaatcctga gtttgctgat agcttcgtgg tgaaataccc
    73021 gtccatttta ctgtcagttt cacagatggc tgaagtcggt ttcattctga cgataccgtt
    73081 ctttttgaag cgtttcggta ttaaaaccgt catgctgatg agtatggtgg cgtggacgct
    73141 gcgctttggc ttctttgcct atggcgatcc atcaccaacc gggtttattt tgctgttgct
    73201 gtcgatgatt gtttacggtt gtgcattcga tttcttcaat atttctggtt cggtctttgt
    73261 cgaacaggaa gttgattcca gcattcgtgc cagcgcccag ggccttttta tgacgatggt
    73321 aaatggcgtc ggcgcatggg ttggctcgat tctgagcggt atggcagtgg attacttctc
    73381 ggtggatggc gtaaaagatt ggcataccat ttggctgatg tttgcagggt atgctctttt
    73441 cctcgcagtg atatttttct ttgggtttaa atataaccat gaccctgaaa agataacgca
    73501 tcgttcagtt acacattaaa aggattcgca gctctgttcc ttggggctgc ttttatgata
    73561 aaggttaatt agtgaaagat attttatttt cttctggcgt tggttttggc attggtgctt
    73621 tgtttacaat cgtgcgatta cctattcctg ttccaaatgt attgccgggt atattatcca
    73681 tcgtgtttat gtatgtcgga tatctggtgg tgaaatactt tatgccatga taatttaata
    73741 cgatgtattt attatatgga gcacttaatt atggaacgcg tatatagaac agatcttaag
    73801 ttgctccgtt attttcttgc cgtagcggaa gagttgcatt ttggtcgcgc agcagcgcgt
    73861 ttaaatatgt ctcagcctcc gctcagtatt catattaaag agctggaaaa tcaactcggc
    73921 acgcagcttt ttattcgcca ttcgcgcagc gtcgtactga cacacgcggg caaaatcttg
    73981 atggaagaat cgcgtcgatt gctggtgaat gcaaataatg tattggctcg ggttgaacaa
    74041 ataggtcggg gagaagcagg gcggattgaa ctcggggttg tgggaacggc aatgtgggga
    74101 cggatgcgcc cggttatgcg gcgattcctt agagaaaatc ctaacgttga agttctgttt
    74161 cgcgaaaaga tgcccgcgat gcaaatggcc ttgctggaac gccgcgaact tgatgccggg
    74221 atctggcgaa tggcgacaga accaccgact ggttttacca gcttacggtt gcatgaatcg
    74281 gcgtttctgg tggcgatgcc tgaagagcat catctctcat cattttccac cgtcccgctg
    74341 gaagcgctac gtgacgagta tttcgttaca atgccgcccg tgtacactga ctgggatttt
    74401 ttgcagcgag tttgccagca ggtgggattt tcaccggttg ttattcgcga agttaatgaa
    74461 ccgcaaacgg tactcgccat ggtcagtatg ggtattggta tcacattgat agcggacagc
    74521 tacgcgcaga tgaactggcc cggtgtcata ttccgtccgc tcaaagaacg catcccggca
    74581 gacttatata ttgtttatga aacgcagcag gtgacgcccg cgctggttaa actgctggcg
    74641 gcgttggcgc agtagatgag aggcacggga actgccggac atagttggtc tgataagcga
    74701 agcgcatcag gcaatttcgc aaattgcaga tagcaaaaaa acgcctttag ggcgcttttt
    74761 tacattggtg ggtcgtgcag gattcgaacc tgcgaccaat tgattaaaag tcaactgctc
    74821 taccaactga gctaacgacc cgaagtggtg ggtgatgacg ggatcgaacc gccgaccccc
    74881 tccttgtaag ggaggtgctc tcccagctga gctaatcacc cacttcggta cttcacattg
    74941 ttacaagaaa tctagctggc gagaaagtgg tgggtgatga cgggatcgaa ccgccgaccc
    75001 cctccttgta agggaggtgc tctcccagct gagctaatca cccacttctc aatttcttgc
    75061 tacacggcgg agactacata aagtagttgg tgggtgatga cgggatcgaa ccgccgaccc
    75121 cctccttgta agggaggtgc tctcccagct gagctaatca cccccgctgt gtggagtcgc
    75181 attataggga gagttcaaaa tgagtcaacg cattttctaa agaaattgtt cgttcgtcgt
    75241 aaatttaagc aagatgatcg caaaacagac cgtgttgcgc aatttgtcaa cgaaaacaat
    75301 aatgcgtaag gttgcaaccc gaactacatt gaggaatcag gcgggagtga tagaatatcg
    75361 cccactcaat ttttccagga tttgccggtt gtcggcatct ttctaaacgt aaggccattt
    75421 catgaaaatc aaaactcgct tcgcgccaag cccaacaggc tatctgcacg ttggcggcgc
    75481 gcgtactgct ctttactcct ggctttttgc acgtaaccac ggcggtgagt tcgtgctgcg
    75541 tattgaagac accgatcttg agcgttccac gccggaagct atcgaagcca ttatggatgg
    75601 catgaactgg ctgagcctgg agtgggatga aggtccgtac taccagacca aacgttttga
    75661 tcgctacaac gcggtgatcg atcagatgct ggaagagggc acagcttata aatgctattg
    75721 ctctaaagag cgcctggaag cgctgcgcga agagcaaatg gcgaaaggtg agaagccgcg
    75781 ttatgacggt cgctgccgcc acagtcatga gcatcacgct gatgatgagc cgtgtgtcgt
    75841 acgttttgct aacccgcagg aaggttctgt tgtttttgac gatcagatcc gtggtccgat
    75901 cgagttcagc aaccaggagc tggatgatct gattatccgc cgtaccgatg gttccccaac
    75961 ctataacttc tgtgtggttg tcgatgactg ggatatggaa atcacccacg ttatccgtgg
    76021 cgaagaccat atcaacaaca caccgcgcca gattaacatt cttaaggctc tgaaagcgcc
    76081 ggtaccggtt tatgcgcacg tttctatgat caacggcgat gacggtaaaa aactgtccaa
    76141 acgtcacggg gcggtcagcg taatgcagta tcgtgatgat ggttatctgc cagaagcact
    76201 gctgaactat ctggtgcgtc tgggctggtc ccacggcgat caggaaatct tcactcgtga
    76261 agagatgatt aaatacttca ctctgaatgc cgtcagcaaa tctgccagtg cgttcaacac
    76321 cgacaagctg ctgtggctga accatcacta cattaacgcg ttgccgccgg agtatgttgc
    76381 tactcactta cagtggcaca ttgagcagga aaatatcgat acccgtaacg gcccgcagct
    76441 ggctgatctg gtgaaactgt tgggcgaacg ctgcaagacg ctgaaagaga tggcacagag
    76501 ctgccgttat ttctacgaag attttgctga gttcgatgcc gacgccgcga aaaaacatct
    76561 gcgtccggta gcgcgccagc cgctggaagt ggttcgtgac aaactgactg cgattactga
    76621 ctggaccgct gaaaacgttc atcacgctat tcaggcgacg gcggatgagc tggaagtggg
    76681 tatgggtaaa gttggtatgc cgctgcgtgt cgccgtaacc ggtgcggggc agtctccggc
    76741 gctggatgtt accgttcacg caatcggtaa gacccgcagt atcgagcgta tcaacaaagc
    76801 gctggctttt attgctgaac gcgaaaatca gcagtaatta gcgcataaaa gataaacggc
    76861 aggagagata cccctgccgt tttttattta tgctgattca tctatgtcga gacgagcaag
    76921 aaaattacga attccttcgc gtgacaaaaa ttgcgcaact ttttcttgct cactgtgagt
    76981 catgttgtct attgcgctga tgatttgccg ataagcagga gtgcgaatac ccggtgcgta
    77041 ttcggcaagg ggttcttcgg cttccagaag catcggtgtg ttatggaagg ctggcgtgtt
    77101 ctgaataaac tcgcaaactt gcgtatcgac cagaataagt ctggcacgac cgcctttcac
    77161 gccgggaaat ttttccgttt tccagccttt ttctctgatc caacggttaa cagtttgttt
    77221 agccacaccg aggcattcag ccagttcttc ggtggtcatt ttattgcgta atcttttcat
    77281 attatttgct atcgcgaatc cctaagcgtt gtaacaatcc gataatccct tcccgcagaa
    77341 gcaaggatgt aaactgtttt tgttcaactg gcgtcatctc tttcgccagt gtcaccagca
    77401 acacttcaag cggcgcatca ccagaaaggg ctggcgcttc tccctgacct tctggacgtt
    77461 cagcattgcg aatatattca cgaacctgtt cattgacgtg aaccagtcga gccttgccac
    77521 cctggacgcc tggttttggt gacgttgtcc agccttcctt gcgtacccat ttattaatgg
    77581 tctggcggct atagccggtc agtctggcaa gttcatctgg cgtcatcctc tccttgaaca
    77641 taacaattcc ctgaatgtat gtgggtctat tagtagttca ttttataaca ccactttaca
    77701 ggaaaccgtg acatgaataa ctactgaatg cgagcggttt tccaaaattg ttcatttgcc
    77761 tgatttttca gcgattgaaa ctacacgtgg caatttgccg ttgacacatt cgggcggaat
    77821 tcatatgatg ccgcccgtca actcgacaag ctttacgtga tggggctata gctcagctgg
    77881 gagagcgctt gcatggcatg caagaggtca gcggttcgat cccgcttagc tccaccaaat
    77941 ttcaaaccct cgctgcaaag cgggggtttt ttgtctctgc cttttgccgc ttttgtaata
    78001 cagtctacat cctggcagtg ccgtgtggtg aatgcatcac tgactgcaaa aacagcaaca
    78061 ggctggcccc tgtttgcttc gcgatgcgaa taaacttatt atttgtgtgc ctgaaaaccc
    78121 cgatcagtga gagtagtgta ctcatgtttg tggagcataa cctgataaaa aatatcaaga
    78181 tattcacact agcgtttacg ctcaccgtgg tacttattca gctatcccgt ttaatttcgc
    78241 cacttgctgt tatccattcc aattatatct ttctggcgtg gatgccactg tgcgtaatgc
    78301 tgtcaatctt gtttatcttt ggctggcgtg gtgtcgttcc cattttatgt gggatgtttt
    78361 gcaccaatct gtggaacctt catctcactt ttttacagac cgccgtcatg atcggcagcc
    78421 aggcgtttgc agtcctgtgt gcctgtgcaa tattacgctg gcaattgggg acgcgttggc
    78481 gttatggatt gaccagccga tacgtctggc aacgtctgtt ctggcttggt ttggtggcgc
    78541 cgattggcat caaatgcagc atgtatcttg tgggaaattt ctttgatttt ccgctaaaga
    78601 tatctacctt tttcggcgat gcggatgcca ttttcacggt cgttgatttg ctaagccttt
    78661 tcaccgcagt gctgatttac aacatgcttt tttactatct cacccgcatg attgtaagtc
    78721 cccactttgc acagatattg tggcgtaggg atatcgctcc gtcgttgagc aaagagaaac
    78781 gcgcatttac cttaagctgg ctggcagctc ttagcgtgct gctacttctg atgtgcacac
    78841 cgtatgaaaa tgactttatt gccggttact tggtacctgt tttctttatc atctttaccc
    78901 tcggtgtcgg taagcttcgc tatccgtttt taaatctcac ctgggctgtt tcaacgcttt
    78961 gcctgctgaa ttacaaccag aactttttgc aaggggtact aaccgaatat tcgctggcat
    79021 ttattctcgc agtactgatt tcctttagtg tttgtctgct ctatatggtg cgtatttatc
    79081 atcgtagtga atggcttaac cgccgctggc atttgcaggc gctgaccgat ccgttaacgc
    79141 tcctacccaa ctttcgtgcg ttggaacaag caccggagca agaggcgggc aagagttttt
    79201 gctgcctgcg cattgataat cttgagttta tgagtcgtca ttacggctta atgatgcgcg
    79261 ttcactgtat ccgctcaatt taccgtacgt tgctgccgtt gatgcaggaa aacgaaaagt
    79321 tgtatcaatt gccgggtagt gaactgctgt tagtgctgag cgggccggaa acggaagggc
    79381 gactccagca tatggttaac atcctgaata gtcggcaaat tcactggaac aataccgggc
    79441 tggatatggg ctatggtgct gcctgggggc attttgatgg aaatcaggaa accctgcaac
    79501 ccttgttggg gcagttaagc tggctggcag agcaatcctg cgcacatcat catgtgctgg
    79561 cgctggatag cagagaggag atggtttccg ggcaaaccac taaacaggtg ctattgctga
    79621 ataccattcg cacggcgtta gatcagggtg atttgctgct ctacgcccag ccaattcgca
    79681 acaaagaggg tgaaggttat gatgagatcc tcgcgcgact gaagtatgac ggcggcatta
    79741 tgaccccgga taagtttctg ccccttattg ctcagtttaa ccttagcgcg cgttttgatt
    79801 tgcaagtgct ggaatccttg ttgaagtggc tggcaacaca cccttgcgac aaaaaaggtc
    79861 cacgattttc agtcaattta atgccgctca cgctgctgca aaagaatatt gccgggcgga
    79921 ttattcgtct gtttaagcgt tattacatct ccccgcaggc ggtcattctt gagatcaccg
    79981 aggagcaggc gttttctaac gcagaaagca gcatgtacaa catcgagcag ctgcataagt
    80041 ttggtttccg gattgcgatt gatgactttg gcaccggata tgccaactac gaacggttaa
    80101 agcgtttgca ggctgatatc atcaaaattg atggcgtctt tgtgaaagat atcgtcacga
    80161 acacgctgga tgcgatgatt gtgagatcaa ttaccgatct ggcgaaagcg aagtcattga
    80221 gtgtggtcgc ggagtttgtc gagacgcaac agcagcaggc gctattgcat aagctcgggg
    80281 tgcaatatct gcaagggtat ttgattggtc gcccgcagcc attagccgat taacaggcgt
    80341 aaaaaagccg gggaattatc cccggctttt ttatgtatgg tcttacagca ccagtgctgc
    80401 gattgacgca gacagcacac tcaccagggt agagccgtaa accagtttca gaccgaagcg
    80461 agaaaccacg ttaccttgct cttcattcag gcctttaacc gcacccgcga taatcccgat
    80521 tgaagagaag ttagcgaagg aaaccaggaa cacagagatg atgccttccg cacgcggaga
    80581 gagcgtggaa gcaattttct gcagatccat catcgcaacg aattcgttgg aaaccagttt
    80641 ggtcgccatg atactgccca cttgcagtgc ttcactggaa ggaacaccca tcacccatgc
    80701 aatcggatag aagatgtaac ccaggatgcc ctggaaggag atgctgtagc caaaccagcc
    80761 agtcacggtg gcaaacagtg cgttcagcgc ggcgatcagg gcgataaagc cgatcagcat
    80821 cgccgcaacg ataatggcaa ccttgaaacc tgccagaatg tattcaccca gcatttcgaa
    80881 gaagctctga ccttcgtgca ggttggacat ctgaatattt tcttcactgg catcaacacg
    80941 gtaagggttg atcagcgaca gcacgataaa ggtgctgaac atgttcagta ccagcgccgc
    81001 aacgacgtat ttcggctcca gcatggtcat gtatgcacca acgatggaca tcgacacggt
    81061 ggacatcgcc gttgctgcca tggtgtacat acgattgcgg gagattttgc cgaggatatc
    81121 tttataggca ataaagtttt cagactgacc cagaatcagg gagctgacgg cgttaaagga
    81181 ttccagtttg cccatgccgt tgactttgga gagcaggaaa ccaattgcgc ggataatcac
    81241 cggcaacacg cgaatgtgct ggagaatacc gatcagtgca gagataaaga cgattgggca
    81301 cagcactttc aggaagaaga atgccaggcc ttgatcattc atgctaccaa agacgaagtt
    81361 agtcccttcg ttggcaaaac cgagcagttt ttcgaacatt tcggagaagc ctttcacgaa
    81421 gcccagacca acgtcggagt tcaggaagaa ccacgccagt aacacttcga taacaagcag
    81481 ttgaataaca taacggatac gaattttttt gcggtcgctg cttaccagca gtgcgagaat
    81541 cgcaacaacg gcaagtgcca gtacaaaatg aaggacgcgg tccatatttg ctccaaatat
    81601 gaggcaggtt aaatttccgt gcacattcta tgtaacatgg ttaaggaaaa cgagatctga
    81661 cacacactat aatgacgtcc tgtgacaagc ttcaaaaata gtgatctgtc atacatttct
    81721 gctatgttgt gtatggaagc ggaaggttat gtaaatgtgc taatattaaa cataaccata
    81781 acattcgagt catctatctt ttcgtagtca taatcctggt ctatcagaga aatcatcaca
    81841 acccatttaa atgaatttga taatcattct catttaacgt agcatgaaac atagcaaagg
    81901 ctatgtttta gaggcacaag atgacgaact atcgcgttga gagtagcagc ggacgggcgg
    81961 cgcgcaagat gaggctcgca ttaatgggac ctgcgttcat tgcggcgatt ggttatatcg
    82021 atcccggtaa ctttgcgacc aatattcagg cgggtgccag cttcggctat cagctactgt
    82081 gggttgtcgt ttgggctaac ctgatggcga tgctgattca aatcctctct gccaaactag
    82141 ggattgccac cggtaaaaat ctggcggagc agattcgcga tcactatccg cgtcccgtag
    82201 tgtggttcta ttgggttcag gcagaaatta ttgcgatggc aaccgacctg gcggaattta
    82261 ttggtgcggc gatcggtttt aaactcattc ttggtgtttc gttgttgcag ggcgcggtgc
    82321 tgacggggat cgcgactttc cttattttaa tgctgcaacg tcgcgggcaa aaaccgctgg
    82381 agaaagtgat tggcgggtta ctgttgtttg ttgccgctgc ttacattgtc gagttgattt
    82441 tctcccagcc taacctggcg cagctgggta aaggaatggt gatcccgagt ttacctactt
    82501 cggaggcggt cttcctggcc gcgggcgtgt taggggcgac gattatgccg catgtgattt
    82561 atttgcactc ttcgctcact cagcatttac atggcggttc gcgtcaacaa cgttattccg
    82621 ccaccaaatg ggatgtggct atcgccatga cgattgccgg ttttgttaat ctggcgatga
    82681 tggctacagc tgcggcggcg ttccactttt ctggtcatac tggtgttgcc gatcttgatg
    82741 aggcttatct gacgctgcaa ccgctgttaa gccatgctgc ggcaacggtc tttggattaa
    82801 gcctggttgc tgccgggttg tcctcaacgg tggtggggac gctggcgggg caggtagtga
    82861 tgcagggctt cattcgcttt catatcccgc tgtgggtgcg tcgtactgtc accatgctgc
    82921 cgtcatttat tgtcattctg atgggattag atccgacacg gattctggtt atgagtcagg
    82981 tgctgttaag ttttggtatc gccctggcgc tggttccact gttgattttc accagtgaca
    83041 gcaagttgat gggcgatctg gtgaacagca aacgcgtaaa acagacaggc tgggtgattg
    83101 tggtgctggt agtggcgctg aatatctggt tactggtagg aacggcactg ggattgtagt
    83161 tgaatgagcg tcgcatttgg caccattggc ggatgcggcg taaatgcttt atccgcccta
    83221 cgcgttaaag agctggtttg taggcctgat aagacgcgct agcgtcgcat caggcattgt
    83281 gctccattgg cgaatgtgtt taatggcggt gtccatgtcc gcggcctttt ccacgatgat
    83341 cgtcacgatc gcgccagcct tcacgatagc cacgctcata cgctttacgc ttatcccagc
    83401 cacgatggta gccattatca tgacgccacc agcggttttt acgccattca taattgcggt
    83461 gccagtagtc acggtcgcgc cagtgaccac cgtcccagta attaccgtaa tgatcgcgat
    83521 cgccaatttg taatttgatt gatggcagta gggtgatttc acctgcgttt gccgcaagcg
    83581 gggtaaatgc catcagggcg gccgccagaa acagtgacct gaacattgtt attctccttc
    83641 acgatcgaag ccgtcagcgg cctgttaacg caatattacg gggaggtaaa gcgccgtatc
    83701 atcgccataa ctcttaaatc ataaaggaga gcattttttg ctaaacgtta tcgtggggtg
    83761 gctgttgctt cggacgattg accatcatca tcggcttacc tgctaataac agccatgccg
    83821 ggagcatgac gatacagagc agcggtagca atgtggtatt gggtacaacg actgccgcca
    83881 taaaaagact taaccagcca tcacgtgtta ccaccagcac gatgccgaga atagcgcagg
    83941 aaacggttat tgccgctgga acggcgggta cgtgctcatg cagcatcaac cctaatgcca
    84001 cgccgacaaa cactgccggg aagattcgcc caccgcgaaa gccactggcg gcagcaacga
    84061 ccagggcggc aagttttatc accgccagca aaaagtaatc gctggtgctg aaagcctgat
    84121 ttgccaccat ctgctgcatc tcatccagcc ctttaaacag cgaaaccggt ccaccaataa
    84181 cccccagaat accgagaata aatccgccaa tacccagcac gaacaccgga tttttcattt
    84241 gatgcatcat cgcgtgcaac cgtggtaagc accatacggc gaccatccct gctgcgatgg
    84301 caatcgccgc gacaattgca ccgctgagaa tatcggtcat ttccatctgt ccgtaatgcg
    84361 caatgggcag tgaaaaatga ggatggaaaa ataatccggt agtaagtgca ccagctgctg
    84421 ccgccattaa cggcgcaaag agacgatccc atagcggaac ttcattactg ccatttaagg
    84481 tttgcgaaaa tatcaatgcc gccgcaacag gtgtgccaaa cagcgcgccg atggttccgg
    84541 cagaggctaa aatagtccac tccattcggt tgacgcgcgg taacagacga gcgccaatgg
    84601 cgacggcaag ggcgatattg acggtcatga tcggatgttc cggccccagg ctgacgccgc
    84661 cagcaagacc gagaattaat gctacgataa gtcctggtag cgcagagggc ggaaccggtg
    84721 cgccgatcag cggttcacag gcggggtctg gtccggcatg accctggctg aaacggataa
    84781 ccaaccccac cgcaataccc gttagcgtta atacaccgat gatccagaga ggtgaatcct
    84841 gggctatccc cagagttccc ggcagtcgtt gccagagcaa attctgtaat accgaggcga
    84901 ttttcatcac cacaatcaga ataagactgg acgcaatccc aattgccacg gcggggagcg
    84961 ataataacaa catggttctg gctcgcggat ggagcatgtt ctattcctta tgcggggtca
    85021 gatacttagt ttgcccagct tgcaaaaagg catcgctgca attggtgctg aaacgataaa
    85081 gtaattgtgt gacccagatc gatatttaca gggagcctgc ctttccggcg ttgttgttat
    85141 gcccccaggt atttacagtg tgagaaagaa ttattttgac tttagcggag cagttgaaga
    85201 atgacaaagt atgcattagt cggtgatgtg ggcggcacca acgcacgtct tgctctgtgt
    85261 gatattgcca gtggtgaaat ctcgcaggct aagacctatt cagggcttga ttaccccagc
    85321 ctcgaagcgg tcattcgcgt ttatcttgaa gaacataagg tcgaggtgaa agacggctgt
    85381 attgccatcg cttgcccaat taccggtgac tgggtggcaa tgaccaacca tacctgggcg
    85441 ttctcaattg ccgaaatgaa aaagaatctc ggttttagcc atctggaaat tattaacgat
    85501 tttactgctg tgtcgatggc gatcccgatg ctgaaaaaag agcatctgat tcagtttggt
    85561 ggcgcagaac cggtagaagg taagcctatt gcggtttacg gtgccggaac agggcttggg
    85621 gttgcgcatc tggtccatgt cgataagcgt tgggtaagct tgccaggaga aggcggtcac
    85681 gttgattttg cgccgaatag tgaagaagag ggcattatcc tcgaaatatt gcgtgcggaa
    85741 attggtcatg tttcggcgga acgcgtgctt tctggccctg ggctggtgaa tttgtatcgc
    85801 gcaattgtta aagccgacaa ccgcctgcca gaaaatctca agccaaaaga tattaccgaa
    85861 cgcgcgctgg ctgacagctg caccgattgc cgccgcgcgt tgtcgctgtt ttgcgtcatt
    85921 atgggccgtt ttggcggcaa tctggcgctc aatctcggga catttggcgg cgtgtttatt
    85981 gcgggtggta tcgtgccgcg ctttcttgag ttcttcaaag cctctggttt ccgcgccgca
    86041 tttgaagata aagggcgctt taaggaatat gtccatgata ttccggtata tctcatcgtc
    86101 catgacaatc cgggtcttct cggttccggt gcacatttac gccagacctt aggtcacatt
    86161 ctctaaatcc ttcctgttat atcgggaggt aactctcccg ataatctttt aaatcataca
    86221 gttaattaaa tttttctttg tgtcccctca caaggccgac ctgcgtcaca cttccgtaca
    86281 gcgggattaa ttctccagta aatgcattat ttgtctggta acggcgattt gttttgcacg
    86341 ttcataattt cactcgtcaa ctatcactga acgaggaatt aacgatgagt aagaaactga
    86401 ttgccttatg tgcctgccca atgggcctgg ctcacacttt tatggccgct caggcgctgg
    86461 aagaagcggc ggtagaagcc ggttatgaag tgaaaattga aacccagggc gcggacggta
    86521 tccagaatcg cctgacggcg caggatatcg ccgaagcgac catcatcatc cactccgtgg
    86581 cagttacccc ggaagataac gagcgtttcg aatcacgcga cgtttatgaa atcactttgc
    86641 aggacgcaat taaaaacgct gcgggaatca tcaaagaaat cgaagagatg attgcctctg
    86701 aacaacagta atattcgaca gggataattg ttatggccat taaaaaacgc agtgcaaccg
    86761 ttgtgcatgg cgcatccggt gcggcagcgg cagttaagaa tccgcaggcc tctaaatcca
    86821 gcttctgggg tgaactcccg cagcatgtga tgtcagggat ttcacgcatg gtgccgacct
    86881 taattatggg cggtgtgatc ctcgctttca gtcagctgat tgcttatagc tggcttaaaa
    86941 ttcctgctga tatcggcatc atggatgctc ttaatagcgg gaaattctcc ggtttcgacc
    87001 tctccttact taaatttgcc tggctgtcgc agtccttcgg cggcgtgttg tttggttttg
    87061 caattccgat gtttgctgct tttgtggcga actctatcgg tggcaaactg gcgttcccgg
    87121 ctggttttat cggcggcttg atgtctaccc agccgacgca actgctgaac ttcgatccca
    87181 gcactatgca atgggcgacc tcttcgccgg tgccgtccac cttcattggt gcgctgatta
    87241 tttctatcgt tgccggttac cttgtgaaat ggatgaacca gaaaatccag ttaccggatt
    87301 tcctgttagc gttcaaaacc acatttttgc taccgattct ttccgccatt tttgtcatgc
    87361 tggcgatgta ctacgtcatc accccctttg gtggctggat caacggcggt atccgtaccg
    87421 tgctgaccgc tgcaggtgag aagggcgcac tgatgtacgc aatggggatc gccgcggcga
    87481 cagcaatcga ccttggtggc ccgatcaaca aagcggcagg tttcgttgcc ttcagcttta
    87541 ccactgacca cgtattaccg gtcactgcac gttctatcgc tatcgttatt ccgccgattg
    87601 gtctgggtct ggcgaccatt attgaccgtc gtttaaccgg caaacgcttg ttcaacgccc
    87661 agctttatcc gcagggtaaa accgccatgt tcctggcgtt tatggggatc agtgagggtg
    87721 cgattccgtt tgcactggaa agccctatca ccgccattcc gtcgtatatg gtcggcgcga
    87781 ttgtcggctc aaccgccgct gtctggctgg gcgcagtgca atggttcccg gagtccgcta
    87841 tctgggcatg gccgctggtc actaacctcg gcgtctacat ggcggggatc gcgctggggg
    87901 cagtcataac tgcgctgatg gtggtgttcc tgcgtctgat gatgttccgt aaaggcaaat
    87961 tgttaatcga tagcctgtaa gaaggacaat cctgatgaca ttactcgctt cgctgcgcga
    88021 ctggcttaag gcgcaacaac tggatgcggt gcttctctcc tcacggcaga acaaacagcc
    88081 gcatctgggg atctccaccg gatcaggtta tgtggtgatt agccgtgaaa gtgcgcacat
    88141 tctggtggat tcgcgctatt acgcggatgt agaagcccgc acgcaaggtt accagctgca
    88201 tttgctcgac gcgatgcaca cgcttgccac catcgtcaga caaatcattg ccgatgagca
    88261 gttgcaaacg ctcggttttg aaggccagca ggtgagttgg gaaaccgcgc accgctggca
    88321 gtccgaactc aatgcgaaac tggtgagcgc cacgccggat gtgctgcggc aaatcaaaac
    88381 gccagaagag gtggagaaaa tccgccttgc ctgcgggatt gccgatcgtg gcgcagagca
    88441 tattcgccgc tttattcagg cgggaatgag cgaatgcgag atagccgctg aactggagtg
    88501 gtttatgcgc cagcagggcg cagaaaaagc ctcttttgac accattgtcg ccagcggctg
    88561 gcgtggggcg ctgccgcacg gcaaagccag cgacaagatt gttgcagcgg gcgagtttgt
    88621 cactctcgat ttcggtgcgc tgtatcaggg ctactgctct gatatgacgc gcaccttgct
    88681 ggtgaatggc gaaggggtga gcgccgaatc tcatccgctg tttaacgtct atcagattgt
    88741 cctgcaggca cagctcgcgg caatctctgt aattcgcccc ggcgtgcgct gccagcaggt
    88801 tgacgatgcc gcgcgccgcg tgattaccga ggccggttat ggcaagtttt tcggccataa
    88861 caccggtcat gctatcggta ttgaagtcca tgaagaaccg cgtttttcac cgcgggacac
    88921 cacgacgcta cagccaggta tgttactgac cgtggagcca gggatttatt tgccagggca
    88981 agggggcgtg cgcatcgaag atgtcgtgct ggtcaccccg caaggcgcag aagtgctcta
    89041 cgccgtgccg aaaacagtgt tgctcacggg agaggcataa tggatttatc gctcttaaaa
    89101 gcgttgagcg aggcagatgc gatcgcctcc tcagaacagg aagtacggca gatcctgcgg
    89161 gaagaagcgg atcgcctgca aaaagaagtg cgatttgacg gcctgggatc ggtgctgatc
    89221 cgactcaatg agtcgacagg tccgaaggtg atgatctgtg cgcatatgga cgaagtggga
    89281 tttatggtgc gcagcatctc ccgcgaaggg gcgatcgatg tgttgccggt tggcaatgta
    89341 cgcatggctg cccgccagct tcagtcggtg cgtatcacta cccgtgaaga gtgcaaaatt
    89401 ccaggcctgc ttgacagcga ccggcagggg aatgacgtca gcgccatgcg cgtggacatt
    89461 ggcgcgcgct cctgtgacga agtgatgcag gcaggaattc gtccaggcga tcgcgtcacc
    89521 ttcgatacca cttttcaggt tctccctcac cagcgggtga tggggaaagc ctttgatgac
    89581 cgcctcggtt gctatctgct ggtgacgtta ctgcgtgagc tgcacgacgc cgaactgcct
    89641 gcggaagtgt ggctggtggc aagttccagc gaagaggtgg gattacgcgg cgggcaaact
    89701 gccacccgcg cggtgtcgcc ggatgtcgcc attgtgcttg atactgcctg ctgggcgaaa
    89761 aactttgatt atggcgcagc taaccatcgc cagattggta acgggccgat gctggtgtta
    89821 agcgacaagt cactgattgc gccgccaaaa cttaccgcct ggatcgaaac cgtggcggca
    89881 gaaattggcg taccgttgca gtcagatatg ttcagcaatg gcggcacgga cggtggggcg
    89941 gtgcacttaa ccggcactgg cgtacccaca gtggtgatgg ggcctgcaac ccgccacgga
    90001 cattgcgccg catcgattgc tgactgccgt gacattttgc agatggagca acttttatct
    90061 gcccttattc aacgtcttac gcgtgagacg gttgttcaac tgacggattt cagatgatct
    90121 cctgattaac ccggagcggt tatgttaacg attcaatttc tctgtccttt gcctaacggt
    90181 ctacatgctc gtccggcgtg ggaacttaaa gagcagtgca gccagtggca aagcgaaatc
    90241 acttttatta accatcgcca gaacgcaaag gccgatgcga aaagctcgct ggcgctgatt
    90301 ggcactggca ctttatttaa tgacagttgc agcctgaaca ttagcggtag cgatgaagag
    90361 caggcgcggc gagtgctgga agagtatatc caggtgcgct ttatcgacag cgatagcgtc
    90421 cagccgacgc tggcagaact gacggcgcat ccgctgccgc gttcattaag ccgcctgaac
    90481 ccggatttac tgtacggcaa cgtgctggca agcggcgttg gcgtgggtac actgaccctg
    90541 ttacagagcg acagcctcga cagttatcgg gtgatccctg cgagtgcgca agattccacc
    90601 ctactggagc acagtctggc aacgcttgcc gagcaactga accagcaatt gcgtgagcgt
    90661 gacggcgaaa gcaaaactat cctcagcgcc catttgtcgc tgattcagga tgatgaattt
    90721 gcaggcaata tccgtcacct gatggcagaa cagcatcagg ggctgggggc ggcgatcatc
    90781 agcaatatgg agcaggtttg tgccaaactt tctgcttctg ccagcgatta tctgcgcgag
    90841 cgggtcagcg acattcgcga tatcagcgaa cagttgctgc atatcacctg gccggaacta
    90901 aaaccgcgca ataatctggt gcttgaaaaa ctgaccattc tggtggctga agatttaacc
    90961 ccaagccagt ttttgagcct cgatttaaaa aatcttgcgg gcatgattct ggagaaaacc
    91021 gggcgcacct cgcataccct gatcctggcc cgcgcttcgg cgatcccggt actgagcgga
    91081 ctgccgctgg atgcgattgc ccgttatgcc gggcaacctg cagtgcttga cgcccagtgc
    91141 ggcgtgctgg cgattaaccc gaatgacgcg gtgagcggtt attatcaggt cgcgcagacg
    91201 ctggcggata aacgccaaaa acaacaggcg caagctgccg cgcagctggc ctattcccgt
    91261 gataacaaac gtattgatat tgcggcgaat attggcaccg ctctggaagc cccaggcgcg
    91321 tttgctaacg gcgcggaagg cgttgggctg tttcgtaccg aaatgctcta tatggatcgc
    91381 gacagcgcgc cggacgagca ggaacagttt gaagcgtacc agcaggtgct attggcggcg
    91441 ggcgacaagc cgattatctt ccgcacgatg gacatcggtg gcgataaaag cattccttac
    91501 ctcaacattc cccaggaaga gaacccgttc ctcggctatc gcgcggtacg tatttacccg
    91561 gaatttgctg gcctgttccg cactcaattg cgggcgattt tgcgcgctgc cagtttcggc
    91621 aacgcccagt tgatgatccc aatggtccac agtctcgatc agatcttatg ggtgaagggt
    91681 gagatccaaa aagcgatcgt tgagcttaag cgcgatggcc tgcgtcatgc agagacgatt
    91741 acgctgggta tcatggtgga agtgccgtcg gtgtgctaca tcatcgacca cttctgcgat
    91801 gaggtcgatt tcttcagtat cggttctaac gatatgaccc agtatctgta tgcagtcgat
    91861 cgtaataacc cgcgcgtatc gccgctgtat aacccgatta cgccatcgtt cctgcgcatg
    91921 ttgcagcaga ttgttaccgc tgcgcatcag cgcggcaaat gggtaggtat ttgcggtgaa
    91981 ctgggcggtg aaagtcgtta tctgccgcta ctgctagggc tggggctgga tgagctaagc
    92041 atgagtagcc cgcgtattcc ggcagtgaaa agccagcttc gtcaactgga tagcgaggcg
    92101 tgtcgggaac tggcgcgtca ggcgtgcgag tgccgcagcg cgcaggaaat tgaagcgtta
    92161 cttaccgcgt ttgcgccgga agaagacgtt cgcccactgc tggcactaga gaatatcttt
    92221 gttgatcagt cctttagtaa taaagagcag gcgatccagt tcctgtgcgg taacctcggt
    92281 gttaacgggc gtactgaaca tccgttcgag ctggaagaag atgtctggca gcgggaagag
    92341 attgttacta ctggcgttgg ttttggcgtg gcgatcccgc acaccaaatc acagtggatc
    92401 cgtcattcca gtatcagcat tgcccggttg gtgaaaccgg ttgactggca gtcagaaatg
    92461 ggcgaagtcg aactggtgat catgctgacg ctgggcgcta acgaagggat gaatcatgtg
    92521 aaagtcttct cgcagctggc gcgtaaactg gtgaataaaa acttccgcca gtcgctgttt
    92581 gccgcgcaag atgcacaaag tattctgacg ctgctggaaa cggaattaac cttctgacgt
    92641 tagccctgaa aacgtgcgct atactctccc ggcgtcagac caaactgacg ccggaaaacg
    92701 cgacaaaaat agtcgctatc cggaaacccg caacgctgcg ccacttcatg aatcgacaga
    92761 tgatattttt gcaaaatcat cctcgctttt gccattcgta cccagcgaac atactcgata
    92821 aaacgcattg ttccatgctg agcaaacagt tttgacagat gatttggcgt gatattaaaa
    92881 aactgcgcca cgctctcgcg ggtgagcagc tgggcataat tatcctgaat ccagttacaa
    92941 atgctgtgat agagaaaatc gccgcgcggt tgcgaattgc ccggcggcat attcaccacg
    93001 ttgcggcaaa gatgcagcaa acttaacacc agtggctgaa tgatattctg ctccagcggc
    93061 gaacggctaa gatgggtgag ggcggtaagc atcgcttcac cttcaccgcg ttgcaggctg
    93121 ggaagctgga tctggcgagc aggatgtaac aacgacgtgg tgcggctatc gtaaaacgat
    93181 aacccaagcc aggtcggtgc gaacaccagg cttaacagca gcaccggttt gttgttgacc
    93241 ggtaaattag ccgcgcgtgc tggaataaac agcatttctc cttccaccat acgttgctgc
    93301 tttgcttcca gcagattgcc gtattcgccg cgtagcacga tatccagacg gggaaaatca
    93361 atacataaac tgcccactgg caatgaggta ggctggctgg caaaccagac gcgccccagt
    93421 agttgcgggt taagcaccag gccgctgaac agatcggcga aaaattgttg atcggcgggc
    93481 aagcctggtg ctttcatgaa agttcccgat taaagatgca ttaactggcg gaattcttta
    93541 actttgctgc agctgaccgg cacttcaaaa tccagatctt tcagccgcag aatataggtg
    93601 ttattaaacc acggttcgat ctcgcggatt ttgttcagat tgacacaaaa tgagcgatgg
    93661 cagcggaaaa aatgcgacgg cggcagcttg ctgcaaaact cggtaatgtt catcggcatt
    93721 acgtaggatt cacgccgcgt atagacaaag gtcattttct catgcgcttc ggcgtaatag
    93781 atatcgttaa tgggcgtgac gatgattcgc tcatctttca ccagattaat ggtgtcattc
    93841 tcacgcgtta ccgtcgcggc aggcgtactg ctggtctgct gttgttgcca ggctgcttcc
    93901 agtttttgca gcatcccggt aatgcgtgac tcctgatacg gtttgagaat gtagtcaaac
    93961 gcctccagtt caaacgcttc taccgcatgt tctttccacg cggtgataaa cacaataaac
    94021 ggtttatggg cgaactggct gatgttttgt gccagcaaca caccatccag cgacggaata
    94081 ttgatatcca gaaaaatggc gtcgacgcgg ttatgctgca aaaacttcaa cacgtccaga
    94141 ccgtcgtcaa aggtgccgac aatctccatc tggctgtgct ctttaattag ccagctcagt
    94201 tcctgttgtg ccaggaattc gtcttcaaca atgatgactt tcacaatatc actccggctc
    94261 aaagcaataa ggtagcctgt gaggcgactg gggtgcgttg gttaggaatg taaaacgcaa
    94321 tttccgttcc tggttccagg cggcggatat gcagcccctc gccatacaat aacttcacgc
    94381 gatgatggac attcagcagg ccaattttat tgcccggcat ttcgttcgct tcgacccgct
    94441 caatcacctt tggatcgatg ccgtgcccgg tatctcgcac cgcaatgcgt acccgattac
    94501 cgcactcagc aacgctgatg gtgacaacgc ctttaccttt gcaaggctgg ataccgtgga
    94561 caatggcgtt ttccaccaac ggctggatca gcaggctggg aatgcagcaa ttcacctctt
    94621 catcaatatc atagataacc gtcagcttgt cgccaaagcg ggcctgctca atggcaatat
    94681 agtctttaat ttgatacagc tcttttttga tatcgatttg ctcatcgtct tttaattcaa
    94741 tgttatagcg cagatagcgc gacaaattaa agatcagctg gcgagcagta tccggattca
    94801 gacggattga cgatgaaata gcgttcaaag cgttaaacag gaaatgggga ttaattttgc
    94861 tttgcagggc gcgaagctct gccttatttg ccatttcacg tagctgctcg gcgcgtgaca
    94921 cctcaagttg cgtggagatg atttgtgaca gaccgaccgc catttcctgt aatgacgagg
    94981 ttatctgatg cgcgtggcag tagtaaattt tcagcgttcc ggtcacaacg cctttctccc
    95041 acaatgggat caccagcatg gaatgaatct ctggtgtgcg gtgggcttca tcattgtttt
    95101 taatgatgat tttcccgtaa ttcatcgcct gacgggtagt cgggctaatg aagtcatcgc
    95161 cattctgata gttatgttca cccacgccaa cgtaggccag cacatgatcg gtattagtca
    95221 tcgccaccgc atcggcgtga atgtcatcgc ggataatttc gcagaccttg cgtaatgact
    95281 cgctattgac atggcgaaac agcggcagcg ttttgttggc gatatccagc gccagcttgg
    95341 cctgccgcgc ggcgctggcc tctttttctc cctcaacact ttgtaccagc aacacaataa
    95401 agccgataca gacgctgccg aggatcattg gaatcccgat tttagagacg atatcgatcc
    95461 ccaatgcggt agttggtgcc cagacaatca ccagaatcat ggtcaacgtt tcacacaaca
    95521 tgccgccgag aataccgacg cgccagcgct gtgctttggg gattttcagg ttgatccagc
    95581 ccgatataca acccgccaga atgctggtga taaagcaggg gatcgccgtc acgccgccga
    95641 tgtcaattaa ataacggtga atacccgcaa tcacgccggt aatgatgccc acccacgggc
    95701 caaacagaat cccgcctgac atcaccgcga taatacgtac gttcaccagc gagccttcta
    95761 cgggaacgcc ggaccaggtg ctgaacaggg cgaacagcga gaaaatggcg gtaacggcga
    95821 gcaactcttt tggggagtgc gccgacttgt gcaacagttc gcgaaacagg cggatacgga
    95881 tgagaaagaa caggcagata agcattaacg ctgcccgatc gaagaccgcc agcagcatgt
    95941 tgaatatttc gtgcacgggt gactctgaat aaggattaaa cctctatgat aggtaacctg
    96001 aaggctgatg accagcaggc cttttttgag gaaaaaccac aattttaaaa ggggattgaa
    96061 agataaatgg tgtattagca atgcatctct tgataatgca catcttgttg gtaaatttat
    96121 tgaaattata atgttaataa aatgagtggt aattttcttg ttagcgtaga taaatttcct
    96181 gtttttgaag tggagttcct catttaaagc cattgataaa aatgttctaa aacgctggac
    96241 agacagaaat taatcaggct attttcaaaa cagccaccat cgtggcagcg tcgctcggac
    96301 ggtccgggcg ctaacgttaa tctgaggaaa ttatggctga cactcgccct gaacgtcgct
    96361 ttacgcgcat tgatcgtctc ccgccctacg tttttaacat taccgctgaa ctgaaaatgg
    96421 ctgcgcgtcg gcgcggcgaa gatattatcg atttcagtat gggtaacccg gacggtgcga
    96481 ctccgccgca tatcgtcgaa aaattatgta cggtggccca gcgcccggac acgcatggtt
    96541 actccacttc acgcggcatt ccgcggttac gtcgcgccat ttcccgctgg tatcaggatc
    96601 gctacgacgt tgaaatcgac ccggaatcag aagccatcgt cactattggt tcgaaagagg
    96661 ggctggcgca cctgatgctg gcgacgctgg atcatggtga cacagtgctg gtgccgaatc
    96721 caagctaccc cattcatatt tacggcgcgg tgattgccgg ggcgcaggta cgctcagtgc
    96781 cgctggtgga aggtgtcgac ttcttcaatg aactggagcg cgccattcgt gaaagttatc
    96841 cgaaaccgaa gatgatgatc ctcggcttcc cgtcaaaccc aaccgcgcaa tgcgtggaac
    96901 tggaattctt tgagaaggtt gtggcgctgg ctaaacgcta cgatgtgctg gtggtccacg
    96961 acctggccta tgccgatatc gtctacgatg gctggaaagc gccgtcaatc atgcaggtgc
    97021 cgggcgcacg cgacgtggcg gtcgagttct ttacgctgtc gaaaagctac aacatggcgg
    97081 gctggcgtat cggctttatg gtcggtaaca aaacgctggt cagcgcgttg gcacgtatta
    97141 aaagctatca cgattacggc acctttacgc cgttgcaggt ggcggctatt gcggcgctgg
    97201 agggcgatca acagtgcgtg cgcgatattg ccgaacagta caaacgccgc cgcgatgtgc
    97261 tggtgaaagg gctgcatgaa gcgggctgga tggtcgaaat gcctaaggct tcgatgtatg
    97321 tctgggcgaa aatcccggaa ccgtatgctg ccatgggctc gctggaattt gccaagaaat
    97381 tgcttaacga agcgaaggtc tgtgtctctc cagggattgg ctttggcgac tacggcgaca
    97441 cgcatgtgcg ctttgcactg attgaaaacc gcgaccgtat tcgtcaggcg attcgtggga
    97501 ttaaagcgat gttccgtgcc gacggtttac tacccgccag cagcaaacat attcacgaaa
    97561 acgcggaata aacgccttcg ccagaaatgc aaacaggagc ctaatggctc ctgtttttca
    97621 ttgcacagtt tgcttttaga tcatcagggc aaaagtaccg gcccaaacga tgaccataaa
    97681 agaaatgccc ataaagaaat atttcacttt acatctctcc gcgtaattac tgttacgcct
    97741 gaatgacttc attacacctg atacagtgag ttgacaccgg gcaaaacgac cttaaacgtc
    97801 ctgtatttta ccgtgggcat catcccagaa ttctgagcta aactgctcga gacggcgcta
    97861 atgtacgcct aaaactgaaa cgagacaaga ggcattttct tatttacttt tagtaactta
    97921 caggtgtctc atatcggcga cagtttaatt tctgacggta ataattagat attcagcgaa
    97981 ggaaaaaacc ttaagaaaaa aagccataaa aaccatgagg ttattatggc tgatttgagg
    98041 agggaaagag tgagagccgt ttgttaaatg tataacgacg attcacccac cgggcgcgtt
    98101 ttaaagcgac ggtgtatcca gaggtactgc tccggtgcgc gcatgatctc tttctcgata
    98161 atcttgttca tataggcagc ggcttgattt tcatctgtcg ggtagccttc catctctggg
    98221 gtgatgtaca aacgatatcc gctgtaatcc gcttttctta ccatcgttac ggtcaacatg
    98281 gctgcgccag agagacgaga gaggacatag gtgccattgg ttgtggcgac attttccacc
    98341 gcaaagaacg gcgcgaagga gctgccttta cgaccataat cctgatcggg agcaaaccat
    98401 accgcttcac ctttcttcag tgcactgaca atgccgcgca gattatttct gccgatcatc
    98461 gctttgttag agcgcatgcg accacgggtc tggacccatt ccatcagctg attattatgc
    98521 gggcgatagg tggccatcat tggttggcaa agtcccatca cccgaccgcc cagttccagc
    98581 gacataaaat ggacgccgac aaccattacg ccgcgatttt gcatttgtgc gcgtttaagg
    98641 ttatccagcc cttccacatc aaaccattta cgtacgcgac tgtcgggcca gaaccacgcc
    98701 atgccggttt ctaccagcgc catgccgagt gaacgaaagt tttcggcaat catcttctcg
    98761 cgctcttccg cagaatgctg cgggaaacaa agttccaggt ttttacgggc gatagattca
    98821 cgacgtttca ggaatggtcg cgccattgtg ccgatacgcg tgccgagaaa gcagagaaca
    98881 ggataaggaa gctgtaccca aagccagagt acaccaagcc caaaccacgt gagccagtag
    98941 cgaggatgca gaaactcgcg ggaaaatttg cattttggaa acatagttac cttctgtaga
    99001 tacgaattgt tgtatcgcag aagattccat gtcgacagcg gtacactcaa ttgattaggc
    99061 catcatgtac gacaatggtt cctgtaaaga gtgtaaagac tagtcaggac ataaccacga
    99121 ggagcatgaa tgcggtatct gtactttatc actcgctgac tgctttcagc tactgattat
    99181 taatcgtgca aagtaaatat ttttccgtac gtaacagtct tgcatttaac atgctgtttt
    99241 gattgatgct tagcaaaaat tgccagaggt taaggattgt cttactatta aagtgactga
    99301 agttacaggt tttttagcgc ggcaggaggt tgagctatga tttatttatg gatgtttctc
    99361 gccctgtgta ttgtctgcgt aagcggatac atcggtcagg tactgaacat ggtatcggcg
    99421 atctcttctt tcttcggcat ggtgatcctc gctgcactca tttattactt caccatgtgg
    99481 ttaactggcg gtaatgaact ggtgacgggg atatttatgt ttcttgcccc ggcttgtggc
    99541 ttgatgattc gctttatggt ggggtatggc aggcgatagt gggtcaggat ggctcatttg
    99601 ggcaggtgtt cacatcagca tcagacatga ttgttcacct gccaggtgac agacgctatc
    99661 gcaaaggatg aatgagataa ttcgcctttg tcggataagt aggcgtgatg tcttctgtga
    99721 ggtttaatgg tggtgcatct tctctcatct taaacaaaat cgcctgtgat ggctgaagtt
    99781 ttgtagaatg cgttgtcgtc atcactgacg ttttttctgt ctctttatag ctcgcctcac
    99841 taccaccacc agaaatagaa aatgcaaaaa cattgcatgc cataatagag acaaataaaa
    99901 ataagctaaa aagcattaag tttactttca tagaaaatat cctggaaatg gttcactgaa
    99961 aacctacgat gttatggctg tattta
//
LOCUS       DAPOXO010000004        93791 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPOXO010000004 DAPOXO010000000
VERSION     DAPOXO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 93791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93791
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.004"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..707)
                     /locus_tag="ROH59_000400"
     CDS             complement(<1..707)
                     /locus_tag="ROH59_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE9 sensor domain-containing protein"
                     /protein_id="HDX4802935.1"
                     /translation="MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRAD
                     SRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVL
                     DDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSMASDDSNNSW
                     NPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDHISANDEVLF
                     LKQGHEIIAKNQLAREK"
     gene            complement(884..1795)
                     /gene="gsiD"
                     /locus_tag="ROH59_000401"
     CDS             complement(884..1795)
                     /gene="gsiD"
                     /locus_tag="ROH59_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HDX4802936.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(1798..2718)
                     /gene="gsiC"
                     /locus_tag="ROH59_000402"
     CDS             complement(1798..2718)
                     /gene="gsiC"
                     /locus_tag="ROH59_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HDX4802937.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGILLIQVFSVELG
                     WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            complement(2736..4274)
                     /gene="gsiB"
                     /locus_tag="ROH59_000403"
     CDS             complement(2736..4274)
                     /gene="gsiB"
                     /locus_tag="ROH59_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HDX4802938.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKEVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGLTYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFHPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQAALLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            complement(4294..6165)
                     /gene="gsiA"
                     /locus_tag="ROH59_000404"
     CDS             complement(4294..6165)
                     /gene="gsiA"
                     /locus_tag="ROH59_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HDX4802939.1"
                     /translation="MPHSDELDAGDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQSAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEHPAKQESSIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVT
                     REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLS
                     PGKLQALRRDIQFIFQDPYASLDPRQTIGDSILEPLRVHGLLPGKEAAARVAWLLERV
                     GLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD
                     LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAA
                     VPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR"
     gene            complement(6152..7117)
                     /gene="iaaA"
                     /locus_tag="ROH59_000405"
     CDS             complement(6152..7117)
                     /gene="iaaA"
                     /locus_tag="ROH59_000405"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDX4802940.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLV
                     AGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACLMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFAHGMERVSPEIFSTPLRYEQLMAAREEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            7321..8556
                     /gene="moeA"
                     /locus_tag="ROH59_000406"
     CDS             7321..8556
                     /gene="moeA"
                     /locus_tag="ROH59_000406"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDX4802941.1"
                     /translation="MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDV
                     VSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQTDNGVRFTAEARSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASPLKKSPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VEVGEWVEVEPFNALFGGL"
     gene            8556..9305
                     /gene="moeB"
                     /locus_tag="ROH59_000407"
     CDS             8556..9305
                     /gene="moeB"
                     /locus_tag="ROH59_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HDX4802942.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLVVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIA
                     ITPVNALLDDAELAAMIAKHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(9381..10043)
                     /gene="fsa"
                     /locus_tag="ROH59_000408"
     CDS             complement(9381..10043)
                     /gene="fsa"
                     /locus_tag="ROH59_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDX4802943.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAVGKKPLEVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDARKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRT
                     SI"
     gene            10174..11073
                     /locus_tag="ROH59_000409"
     CDS             10174..11073
                     /locus_tag="ROH59_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDX4802944.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDPRLCLEGCELCAKTAPEVIERALNGLLIHREKLTPEHFTALTDCCPTQALTVCGE
                     VKSVEEIMATVLRDKPFYDRSGGGLTLSGGEPFMQPEMATALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLSYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIR
                     VPLIQGFNADETSVKAITDFAADELHVSEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            11079..13511
                     /locus_tag="ROH59_000410"
     CDS             11079..13511
                     /locus_tag="ROH59_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDX4802945.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMAATETRESRRDELLTIAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            13657..14472
                     /gene="ybiV"
                     /locus_tag="ROH59_000411"
     CDS             13657..14472
                     /gene="ybiV"
                     /locus_tag="ROH59_000411"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HDX4802946.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIEFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHITLDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMSNAAENIKQIARYATDDNNHEGALNVIQAVLENKPPFNL"
     gene            complement(14672..16264)
                     /locus_tag="ROH59_000412"
     CDS             complement(14672..16264)
                     /locus_tag="ROH59_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HDX4802947.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIE"
     gene            16483..17403
                     /gene="ldtB"
                     /locus_tag="ROH59_000413"
     CDS             16483..17403
                     /gene="ldtB"
                     /locus_tag="ROH59_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDX4802948.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            complement(17461..18579)
                     /locus_tag="ROH59_000414"
     CDS             complement(17461..18579)
                     /locus_tag="ROH59_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000056422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HDX4802949.1"
                     /translation="MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKALQYHTGGQTPEWKPRLVWSCLGLYIVFLTALE
                     LKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPVLQGVLSNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLAWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLLWAALVGYVLLVMIPAG"
     gene            complement(18576..19043)
                     /gene="mntR"
                     /locus_tag="ROH59_000415"
     CDS             complement(18576..19043)
                     /gene="mntR"
                     /locus_tag="ROH59_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HDX4802950.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            19229..19357
                     /gene="mntS"
                     /locus_tag="ROH59_000416"
     CDS             19229..19357
                     /gene="mntS"
                     /locus_tag="ROH59_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HDX4802951.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            19629..21212
                     /gene="opgE"
                     /locus_tag="ROH59_000417"
     CDS             19629..21212
                     /gene="opgE"
                     /locus_tag="ROH59_000417"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDX4802952.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGISSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYLVGIFIFALGVIAIRRKKESEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(21261..21776)
                     /gene="ompX"
                     /locus_tag="ROH59_000418"
     CDS             complement(21261..21776)
                     /gene="ompX"
                     /locus_tag="ROH59_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HDX4802953.1"
                     /translation="MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(21829..21894)
                     /locus_tag="ROH59_000419"
     CDS             complement(21829..21894)
                     /locus_tag="ROH59_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4802954.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            22129..23016
                     /gene="rhtA"
                     /locus_tag="ROH59_000420"
     CDS             22129..23016
                     /gene="rhtA"
                     /locus_tag="ROH59_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HDX4802955.1"
                     /translation="MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGSTLTVRKESKIKELDIN"
     gene            23316..23819
                     /gene="dps"
                     /locus_tag="ROH59_000421"
                     /gene_synonym="pexB"
     CDS             23316..23819
                     /gene="dps"
                     /locus_tag="ROH59_000421"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HDX4802956.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
     gene            24223..24969
                     /gene="glnH"
                     /locus_tag="ROH59_000422"
     CDS             24223..24969
                     /gene="glnH"
                     /locus_tag="ROH59_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HDX4802957.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            25108..25767
                     /gene="glnP"
                     /locus_tag="ROH59_000423"
     CDS             25108..25767
                     /gene="glnP"
                     /locus_tag="ROH59_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HDX4802958.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            25764..26486
                     /gene="glnQ"
                     /locus_tag="ROH59_000424"
     CDS             25764..26486
                     /gene="glnQ"
                     /locus_tag="ROH59_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HDX4802959.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     DPQVLIKNPPSQRLQEFLQHVS"
     gene            26603..28828
                     /gene="ybiO"
                     /locus_tag="ROH59_000425"
     CDS             26603..28828
                     /gene="ybiO"
                     /locus_tag="ROH59_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HDX4802960.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYCKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKTVLRLIFCPNVAELRPFTIHDETARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLVIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGAAPAEPLPPGEPT
                     L"
     gene            complement(28825..29751)
                     /gene="rlmF"
                     /locus_tag="ROH59_000426"
     CDS             complement(28825..29751)
                     /gene="rlmF"
                     /locus_tag="ROH59_000426"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HDX4802961.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            30027..30287
                     /locus_tag="ROH59_000427"
     CDS             30027..30287
                     /locus_tag="ROH59_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX4802962.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTAIIYK"
     gene            30552..32834
                     /locus_tag="ROH59_000428"
     CDS             30552..32834
                     /locus_tag="ROH59_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
                     /protein_id="HDX4802963.1"
                     /translation="MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQANADDTL
                     VVEASTPSLYAPQKSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVG
                     AFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
                     YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGE
                     KTHDAGRDKVKNERYGVAPSVAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGFSA
                     PSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVK
                     QDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGAIGH
                     DVSTGVEFTRETQTNYGVNPVTLPTVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYA
                     FDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPAGVAKGSPVTTVDTAK
                     SGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKA
                     NTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNI
                     TPAWQMIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGAR
                     YIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKS
                     GYRYHPGEPRTFLLTANMHF"
     gene            32876..33553
                     /gene="ybiX"
                     /locus_tag="ROH59_000429"
     CDS             32876..33553
                     /gene="ybiX"
                     /locus_tag="ROH59_000429"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HDX4802964.1"
                     /translation="MMYHIPGVLSPQDVARFREHLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSALYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPESYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSHYGESEEILSLLNLYHNL
                     LREWSEI"
     gene            33627..33893
                     /gene="ybiI"
                     /locus_tag="ROH59_000430"
     CDS             33627..33893
                     /gene="ybiI"
                     /locus_tag="ROH59_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HDX4802965.1"
                     /translation="MASGWANDDAVNEQINSTIEDAIARARGEIPRGESLYECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            34158..34418
                     /locus_tag="ROH59_000431"
     CDS             34158..34418
                     /locus_tag="ROH59_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX4802966.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(34556..35641)
                     /gene="hcxB"
                     /locus_tag="ROH59_000432"
     CDS             complement(34556..35641)
                     /gene="hcxB"
                     /locus_tag="ROH59_000432"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcXB"
                     /protein_id="HDX4802967.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKVVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCSAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGS
                     WQAICDAARQIGMPEETLQAFCQQLAS"
     gene            complement(35781..36743)
                     /gene="ybiB"
                     /locus_tag="ROH59_000433"
     CDS             complement(35781..36743)
                     /gene="ybiB"
                     /locus_tag="ROH59_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HDX4802968.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDTAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLMATGEAATISDGLARVNQAF"
     gene            complement(36771..38921)
                     /gene="dinG"
                     /locus_tag="ROH59_000434"
     CDS             complement(36771..38921)
                     /gene="dinG"
                     /locus_tag="ROH59_000434"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HDX4802969.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSIDNEEQHIAEMAAFFREQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGALLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            39025..39225
                     /locus_tag="ROH59_000435"
                     /pseudo
     CDS             39025..39225
                     /locus_tag="ROH59_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1768 domain-containing protein"
     gene            complement(39458..40819)
                     /gene="rhlE"
                     /locus_tag="ROH59_000436"
     CDS             complement(39458..40819)
                     /gene="rhlE"
                     /locus_tag="ROH59_000436"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HDX4802970.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAILGYEPDPSIKAEPIQNGRQ
                     QRGGGRGQGGGRGQQQPRRAESGAKSGNAKPAEKPSRRLGDAKPAGEQQRRRRPRKPA
                     AAQ"
     gene            41048..41719
                     /gene="cecR"
                     /locus_tag="ROH59_000437"
     CDS             41048..41719
                     /gene="cecR"
                     /locus_tag="ROH59_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HDX4802971.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     SDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            41722..42717
                     /gene="hlyD"
                     /locus_tag="ROH59_000438"
     CDS             41722..42717
                     /gene="hlyD"
                     /locus_tag="ROH59_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HDX4802972.1"
                     /translation="MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTV
                     NLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRA
                     VEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE"
     gene            42710..44446
                     /locus_tag="ROH59_000439"
     CDS             42710..44446
                     /locus_tag="ROH59_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415315.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4802973.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGSATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPTALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKETTPD
                     DIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHSNE"
     gene            44439..45572
                     /locus_tag="ROH59_000440"
     CDS             44439..45572
                     /locus_tag="ROH59_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4802974.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANAIAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLIVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            45583..46689
                     /locus_tag="ROH59_000441"
     CDS             45583..46689
                     /locus_tag="ROH59_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4802975.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(46651..47061)
                     /locus_tag="ROH59_000442"
     CDS             complement(46651..47061)
                     /locus_tag="ROH59_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HDX4802976.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            47194..47955
                     /locus_tag="ROH59_000443"
     CDS             47194..47955
                     /locus_tag="ROH59_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDX4802977.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGESVLVAGDFNDWRQKANHPLKVLAGLDEIFTRAHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            47952..49193
                     /gene="clsB"
                     /locus_tag="ROH59_000444"
     CDS             47952..49193
                     /gene="clsB"
                     /locus_tag="ROH59_000444"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HDX4802978.1"
                     /translation="MKCSWREGNMIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSTARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRNFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            49193..50149
                     /locus_tag="ROH59_000445"
     CDS             49193..50149
                     /locus_tag="ROH59_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HDX4802979.1"
                     /translation="MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGVIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVSYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGT
                     IIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM"
     gene            complement(50185..50898)
                     /locus_tag="ROH59_000446"
     CDS             complement(50185..50898)
                     /locus_tag="ROH59_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDX4802980.1"
                     /translation="MESYSQNSNKLDFQHEARILNGIWLITALGLVATAGLAWGAKYL
                     EITATKYDSPQMYVAIGLLLLSMYGLSKDINKINTAIAGVIYLFLISLVAIVVASLAP
                     VSAIIVVFSTAGSMFLISMLAGLLFKFDPGSHRFIIMMTLTGLALVIIVNATLMSERP
                     IWVISCLMIVLWSGIISHGRNKLLELTGKSHSEELWSPVRCAFIGALTLYYYFIGFFG
                     ILAAIAITLVWQRHTRFFH"
     gene            complement(51104..51808)
                     /locus_tag="ROH59_000447"
     CDS             complement(51104..51808)
                     /locus_tag="ROH59_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDX4802981.1"
                     /translation="MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            complement(51945..52397)
                     /gene="moaE"
                     /locus_tag="ROH59_000448"
     CDS             complement(51945..52397)
                     /gene="moaE"
                     /locus_tag="ROH59_000448"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HDX4802982.1"
                     /translation="MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVKALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            complement(52399..52644)
                     /gene="moaD"
                     /locus_tag="ROH59_000449"
     CDS             complement(52399..52644)
                     /gene="moaD"
                     /locus_tag="ROH59_000449"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HDX4802983.1"
                     /translation="MINVLFFAQVRELVGTDATEVAADFPTVEALRQHLAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHSLTDGDEVAFFPPVTGG"
     gene            complement(52637..53122)
                     /gene="moaC"
                     /locus_tag="ROH59_000450"
     CDS             complement(52637..53122)
                     /gene="moaC"
                     /locus_tag="ROH59_000450"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDX4802984.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            complement(53125..53637)
                     /gene="moaB"
                     /locus_tag="ROH59_000451"
     CDS             complement(53125..53637)
                     /gene="moaB"
                     /locus_tag="ROH59_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HDX4802985.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            complement(53659..54648)
                     /gene="moaA"
                     /locus_tag="ROH59_000452"
     CDS             complement(53659..54648)
                     /gene="moaA"
                     /locus_tag="ROH59_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDX4802986.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLENDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     regulatory      complement(54636..54780)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            55045..55953
                     /gene="yvcK"
                     /locus_tag="ROH59_000453"
     CDS             55045..55953
                     /gene="yvcK"
                     /locus_tag="ROH59_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HDX4802987.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDAHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTAP
                     IQELLLTPNVPATREAVHAISEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVL
                     EASDIPYRHDRQLLHSALEKALQALG"
     gene            complement(55991..58012)
                     /gene="uvrB"
                     /locus_tag="ROH59_000454"
     CDS             complement(55991..58012)
                     /gene="uvrB"
                     /locus_tag="ROH59_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HDX4802988.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(58591..59268)
                     /gene="bioD"
                     /locus_tag="ROH59_000455"
     CDS             complement(58591..59268)
                     /gene="bioD"
                     /locus_tag="ROH59_000455"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDX4802989.1"
                     /translation="MSKCYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGS
                     EKTPKGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIEALVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QAILHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLALM"
     gene            complement(59261..60016)
                     /gene="bioC"
                     /locus_tag="ROH59_000456"
     CDS             complement(59261..60016)
                     /gene="bioC"
                     /locus_tag="ROH59_000456"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HDX4802990.1"
                     /translation="MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYT
                     RVLDAGCGPGWMSRRWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRFLPPDEIEQSLNAVHYQHYIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE"
     gene            complement(60003..61157)
                     /gene="bioF"
                     /locus_tag="ROH59_000457"
     CDS             complement(60003..61157)
                     /gene="bioF"
                     /locus_tag="ROH59_000457"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HDX4802991.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVVDDRQYLNF
                     SSNDYLGLSHHPQIIRAWKQGAEQFGIGSGGSGHVSGYSVAHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSPLRRFAHNDVTHLAR
                     LLASPCPGQQLVVTEGVFSMDGDSAPLEEIQQVTQQHDGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSNTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSWSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG"
     gene            complement(61154..62194)
                     /gene="bioB"
                     /locus_tag="ROH59_000458"
     CDS             complement(61154..62194)
                     /gene="bioB"
                     /locus_tag="ROH59_000458"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDX4802992.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            62281..63570
                     /gene="bioA"
                     /locus_tag="ROH59_000459"
     CDS             62281..63570
                     /gene="bioA"
                     /locus_tag="ROH59_000459"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HDX4802993.1"
                     /translation="MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHNLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQH
                     QVAAIEAQLREQLAPACDAEMVADVRVLGAIGVVETSRPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILSQQLQRLTAAVNRAVQDETFFCQ"
     gene            63629..64105
                     /locus_tag="ROH59_000460"
     CDS             63629..64105
                     /locus_tag="ROH59_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HDX4802994.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPVGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDVERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            64257..65540
                     /locus_tag="ROH59_000461"
     CDS             64257..65540
                     /locus_tag="ROH59_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HDX4802995.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDKVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     ASGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVD
                     DNDEVQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(65681..67942)
                     /locus_tag="ROH59_000462"
     CDS             complement(65681..67942)
                     /locus_tag="ROH59_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HDX4802996.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVAALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSEMAEVFARIKQIAGQEHVDPL
                     QTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEAPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(68125..69558)
                     /locus_tag="ROH59_000463"
     CDS             complement(68125..69558)
                     /locus_tag="ROH59_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HDX4802997.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSGGEFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGSTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            complement(69634..70686)
                     /locus_tag="ROH59_000464"
     CDS             complement(69634..70686)
                     /locus_tag="ROH59_000464"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HDX4802998.1"
                     /translation="MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGND
                     LEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGA
                     FAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
                     LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELD
                     ADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRA
                     LAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRAS
                     VIRTTRKIFSGEVYLP"
     gene            70870..71823
                     /locus_tag="ROH59_000465"
     CDS             70870..71823
                     /locus_tag="ROH59_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308823.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4802999.1"
                     /translation="MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEED
                     LHIQLFERTTRKVTLTKAGKRLLPEVRELIKKFDETLFSIRDMNAYHRGMVTLACIPT
                     AVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
                     PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLD
                     WFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKD
                     AVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG"
     gene            complement(71864..72859)
                     /gene="pgl"
                     /locus_tag="ROH59_000466"
     CDS             complement(71864..72859)
                     /gene="pgl"
                     /locus_tag="ROH59_000466"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HDX4803000.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            73014..73832
                     /gene="ybhA"
                     /locus_tag="ROH59_000467"
     CDS             73014..73832
                     /gene="ybhA"
                     /locus_tag="ROH59_000467"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyridoxal
                     phosphate/fructose-1,6-bisphosphate phosphatase"
                     /protein_id="HDX4803001.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            complement(73833..74891)
                     /gene="modC"
                     /locus_tag="ROH59_000468"
     CDS             complement(73833..74891)
                     /gene="modC"
                     /locus_tag="ROH59_000468"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HDX4803002.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDADKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMA
                     KSMVNQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGCKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(74894..75583)
                     /gene="modB"
                     /locus_tag="ROH59_000469"
     CDS             complement(74894..75583)
                     /gene="modB"
                     /locus_tag="ROH59_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDX4803003.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGLSFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            complement(75583..76356)
                     /gene="modA"
                     /locus_tag="ROH59_000470"
     CDS             complement(75583..76356)
                     /gene="modA"
                     /locus_tag="ROH59_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4803004.1"
                     /translation="MARKWLNLFTGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTASRQ
                     TLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK"
     gene            complement(76523..76672)
                     /gene="acrZ"
                     /locus_tag="ROH59_000471"
     CDS             complement(76523..76672)
                     /gene="acrZ"
                     /locus_tag="ROH59_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump accessory protein AcrZ"
                     /protein_id="HDX4803005.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            76801..77589
                     /gene="modE"
                     /locus_tag="ROH59_000472"
     CDS             76801..77589
                     /gene="modE"
                     /locus_tag="ROH59_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HDX4803006.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            77657..79129
                     /gene="modF"
                     /locus_tag="ROH59_000473"
     CDS             77657..79129
                     /gene="modF"
                     /locus_tag="ROH59_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HDX4803007.1"
                     /translation="MSSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSA
                     LARALSGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTT
                     AEIIQDEVKDTSRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQHLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSELLEGVQMPEPDEPSARHALPANEPRIVLNNGVVSYNERPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGGLYRYVLTKIN"
     gene            79392..80408
                     /gene="galE"
                     /locus_tag="ROH59_000474"
     CDS             79392..80408
                     /gene="galE"
                     /locus_tag="ROH59_000474"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308814.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDX4803008.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGSSVLDVVNAF
                     SKACGKPVNYHFAPRRAGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            80418..81464
                     /gene="galT"
                     /locus_tag="ROH59_000475"
     CDS             80418..81464
                     /gene="galT"
                     /locus_tag="ROH59_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDX4803009.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESNDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQIWANSFLPNEAEREDRLQKEYFAGQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            81468..82616
                     /gene="galK"
                     /locus_tag="ROH59_000476"
     CDS             81468..82616
                     /gene="galK"
                     /locus_tag="ROH59_000476"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDX4803010.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            82610..83650
                     /gene="galM"
                     /locus_tag="ROH59_000477"
     CDS             82610..83650
                     /gene="galM"
                     /locus_tag="ROH59_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HDX4803011.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDVRNHKLQILAEEYLPVDEGGIPHDGLKSVAGT
                     SFDFRNAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAQ"
     gene            83853..84605
                     /gene="gpmA"
                     /locus_tag="ROH59_000478"
     CDS             83853..84605
                     /gene="gpmA"
                     /locus_tag="ROH59_000478"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDX4803012.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(84772..85824)
                     /gene="aroG"
                     /locus_tag="ROH59_000479"
     CDS             complement(84772..85824)
                     /gene="aroG"
                     /locus_tag="ROH59_000479"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HDX4803013.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWDDT
                     DALLRQLANAVKARRG"
     gene            86140..86520
                     /locus_tag="ROH59_000480"
     CDS             86140..86520
                     /locus_tag="ROH59_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HDX4803014.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHPDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            86634..87575
                     /gene="zitB"
                     /locus_tag="ROH59_000481"
     CDS             86634..87575
                     /gene="zitB"
                     /locus_tag="ROH59_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HDX4803015.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVIGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRLCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNRGVSGHSHHHH"
     gene            complement(87572..88291)
                     /gene="pnuC"
                     /locus_tag="ROH59_000482"
     CDS             complement(87572..88291)
                     /gene="pnuC"
                     /locus_tag="ROH59_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HDX4803016.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVAMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWIKSARERGSRALSH"
     gene            complement(88329..89372)
                     /gene="nadA"
                     /locus_tag="ROH59_000483"
     CDS             complement(88329..89372)
                     /gene="nadA"
                     /locus_tag="ROH59_000483"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDX4803017.1"
                     /translation="MSVMFDPDTAIYPFPPKPTPLSIDEKANYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVEMADAVGSTSQLIAAAKTLQHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHEVYVDERLRERALVP
                     LNRMLDFAATLRG"
     gene            complement(89650..89725)
                     /locus_tag="ROH59_000484"
     tRNA            complement(89650..89725)
                     /locus_tag="ROH59_000484"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89690..89692),aa:Lys,seq:ttt)
     gene            complement(89759..89834)
                     /locus_tag="ROH59_000485"
     tRNA            complement(89759..89834)
                     /locus_tag="ROH59_000485"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89799..89801),aa:Lys,seq:ttt)
     gene            complement(89883..89958)
                     /locus_tag="ROH59_000486"
     tRNA            complement(89883..89958)
                     /locus_tag="ROH59_000486"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89923..89925),aa:Lys,seq:ttt)
     gene            complement(89962..90037)
                     /locus_tag="ROH59_000487"
     tRNA            complement(89962..90037)
                     /locus_tag="ROH59_000487"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90002..90004),aa:Val,seq:tac)
     gene            complement(90089..90164)
                     /locus_tag="ROH59_000488"
     tRNA            complement(90089..90164)
                     /locus_tag="ROH59_000488"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90129..90131),aa:Lys,seq:ttt)
     gene            complement(90167..90242)
                     /locus_tag="ROH59_000489"
     tRNA            complement(90167..90242)
                     /locus_tag="ROH59_000489"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90207..90209),aa:Val,seq:tac)
     gene            complement(90278..90353)
                     /locus_tag="ROH59_000490"
     tRNA            complement(90278..90353)
                     /locus_tag="ROH59_000490"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90318..90320),aa:Lys,seq:ttt)
     gene            complement(90518..91309)
                     /gene="cpoB"
                     /locus_tag="ROH59_000491"
     CDS             complement(90518..91309)
                     /gene="cpoB"
                     /locus_tag="ROH59_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HDX4803018.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSGDQSGVVASTTPTADAGTSNAGAPVKSGDANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            complement(91319..91840)
                     /gene="pal"
                     /locus_tag="ROH59_000492"
     CDS             complement(91319..91840)
                     /gene="pal"
                     /locus_tag="ROH59_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HDX4803019.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYAKNRRAVLVY"
     gene            complement(91875..93167)
                     /gene="tolB"
                     /locus_tag="ROH59_000493"
     CDS             complement(91875..93167)
                     /gene="tolB"
                     /locus_tag="ROH59_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HDX4803020.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            complement(93300..>93791)
                     /gene="tolA"
                     /locus_tag="ROH59_000494"
     CDS             complement(93300..>93791)
                     /gene="tolA"
                     /locus_tag="ROH59_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HDX4803021.1"
                     /translation="AADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADDIFGELS
                     SGKNAPKTGGGAKGNNASPAGSGNTKNNGASGADINNYAGQIKSAIESKFYDASSYAG
                     KTCTLRIKLAPDGMLLDIKPEGGDPALCQAALAAAKLAKIPKPPSQAVYEVFKNAPLD
                     FKP"
BASE COUNT        22783 a        25030 c        23546 g        22432 t
ORIGIN      
        1 aatttttcac gagcgagttg attcttagca atgatctcat gaccttgctt taaaaataga
       61 acttcatcat tagcgctgat gtgatcaaga tactcgttca gatatcgcca gtttaaatcg
      121 acatgaattt tatctaccgc taacaaatca tgatctttgc cgttgatgtg tagcgtaaaa
      181 gagatacatt ttttacccgg acgatcaaag caattgtatg ccgggttcca gctgttgtta
      241 gagtcatctg aagccatcga ccacggtcgt ttcgatgggt taaaatcggc aaaaataacc
      301 cgccctgact cgtcgacaag cggtccattt acttgttcct gatgataaac aacgatttta
      361 tcattcgccc tccgcgaaaa gagataatat ttattatcat caagtaccag tcccaccgag
      421 tctaaaaatg gcatcatttc cattttcaga atcacggcac gttgaatctc ctctgtattt
      481 tttaataaat acagtgagtc ctttaatgtc agggccgaac gttcaatatc tttaaagaaa
      541 tagccaacgt ttttctgaat aagttcaaag cggctatcgg cacgttttac cgcgcgttcc
      601 gataccagtt gatagttaat gatgaaaaaa agaccaataa atgacaatgc tgccaataaa
      661 aataaaatta tcagccttat ctttatcttt tcgtataaac tcagcatgtt aatacattta
      721 aaaaaataac tgtctgaacg ctgtgccgct gcaaaatagt cccttgctgc ggctttttaa
      781 ccaaattacc cgattctaca aaatcagcag aaagttacaa cacttgctta gggcaataat
      841 ttcctgtgag gtgattaccc tttcaagcaa tattcaaacg taactatcct ttaattttcg
      901 gatccagcgc atcgcgtaaa ccatcgccca acaaattgaa cgccagtacg gtcagaaaaa
      961 tagccagggc cggaaataca gcgacatgcg gcgcgataac catatccgct cgtgcctcat
     1021 tgagcattgc accccactct ggtgtcggcg gctgcgcacc gaggccgaga aatgacaggc
     1081 tggcggcaga gataatcgag gtgccaatgc gcatggtgaa aaacaccacg atagaagaga
     1141 cggtcccagg caagatatga cgcaacaaaa tggtcatatc gctggcacca atactgcgtg
     1201 ctgactcgat aaaggtttgc tgtttcaaca ccagcgtgtt gccgcgcacc agccgggcaa
     1261 acgcggggat ggaaaaaatg gcgactgcga taatcacgtt agcaatgccg cttcccaaca
     1321 ccgcaacaac agcgatcgcc agtaaaatac ccgggaaggc aaacagcaca tcgcaaatgc
     1381 gcatgatcag ccgatcccac cagccttcat aatatccagc cagcaagccc agcaacgtcc
     1441 cgatcgccgc accgataaac acggcaaaca cgcccgccgc cagcgagatt tgcgcaccaa
     1501 ccaggacacg gctgaaaatg tcgcgcccca gtgaatcgac accaaaccag tgctgcaaag
     1561 aaggtccgtt attcagattg tcataatcaa aataattttc ggcgtcatag ggagcgatcc
     1621 agcgtgcaaa aatggccacc acaatcaata aaataacgaa caatgcggcg gtcatcgcca
     1681 tatgctgacg gcgaaatcgt cgccagaatt catgccacgg tgtacgtacc tggtcaggtt
     1741 tgaccagtgg catggcgttt aacaccgcct gacgtcgcca gttaaatagt cgcatcctta
     1801 cttgtacctg atagccgggt taatggcggc gtaaagcaca tccaccacta agttgataag
     1861 aataaattcc agcgagaaaa gcagaatttc cgcctgaatc actgggtaat cgcgcatttc
     1921 tacggagtca acgagtaagc gtccaagtcc gggccagttg aaaactttct ccaccacgat
     1981 ggaaccaccg agcaagaagc caaactgtaa gcccatcatg gtcactaccg ggatcatcgc
     2041 gttgcgtagc ccgtgtttga ggacaaccca ggtttcgctc acccctttcg ccctcgcggt
     2101 acgcatataa tcttcgctta aaacgtcgac aaacgacgcg cgggtaaagc gcgccatcac
     2161 ggcggccact gccgcgccga gcgtcaggga gggtaaaatg tagtgctgcc aactgtctgc
     2221 tcccacggta ggcagccagc ccagttcaac ggagaatacc tgaattaaaa gtatccccag
     2281 agcaaatgcc ggaaacgaga tccccgacac cgcaatggtc atactcaatc gatccggcca
     2341 acggttacgc cagacggcgg cgataattcc cgccgccata ccaaatatca ccgcccagac
     2401 catactggtt atggtcagcc agagcgttgg cataaagcgg ctggcaatct catcggcaac
     2461 cggacgacgc gacaccatcg acaggccaaa atccccctgc acagcattgc tgatatagtg
     2521 ccagaactgg tgatacagcg gctgatccaa ccccaactgc tgacgcacca gttctataac
     2581 ctgcgcatca gcttcgggcc cggcaatcaa tcgcgccgga tcgccgggca gcatatggac
     2641 aaataaaaac accagcaccg agacgataaa cagcgtcgga atcaacccca gtaagcgttt
     2701 gataacgtaa ttaagcattc cactccctgc gttgcttatt gcaaatccgc gtcttcaaag
     2761 ctgaagccgg tgtctggcat gatccaaaaa ccggtcaggt ttttactgtg tgccgacacc
     2821 agtttttcta ccaccagcgg gatccacggc gactcttgcc agatgatatc ctgcgccgcc
     2881 ttatacaagc gggtcttttc cgccggatca ttagttttca gtgcctgagc caggaagtca
     2941 tccacctgtt tattgctgta aaacgcggta ttaaacagcg ttggtggcca gttctgcgag
     3001 gcaaacagcg gcgatagagc ccagtcggct tcgccggttg aagccgacca gccagtgtag
     3061 aacatccgca cgccgctctc tttttgccct ttaccttcaa cttctgccgc ccgctgtccg
     3121 gcatccatcg cagtcacctg ggctttaatc ccaacctgcg ctaactgctg ctgggtaaat
     3181 tgcagcactt tctgcgcggt gctgtggtta tgtgacgacc acagcgtggt actgaaaccg
     3241 ttgggatatc ccgcctcttt cagtaattcg cgcgctttca ctggatcgta aggccacggt
     3301 ttataacttt gcgcgtaggc gatactcggc ggtaccacac cagtagctgg cgttgcatag
     3361 cccgcgaagg ccactttcac cagcgccggg cggttaatgg cgtaattcag cgcctcacgg
     3421 accttcgggt tatcgaacgg cttttgcgtc acgttcatac tgatataacg ctgcataatt
     3481 gacggactgg ccatcaactc gatatttttg tttttctcca gcagtgcggc ctgctcgtag
     3541 ggaatgggga aagcaaactg cgcttcaccg gtttgcagca ttgccgcgcg ggtgttgtta
     3601 tccgccaccg gacgccaggt tatgctgtcc agtttgggca atcctggctg ccagtaaccc
     3661 gcgaattttt tcaccttcac aaaatcggtc tgattccagg tatccagttc atacggcccg
     3721 gttcccaccg gatgaaaacc aatctccttg ccatattttt ccagcgctgc cggtgatatc
     3781 atcgcggtcg ccggatgggc aagaatatta ataaacgctg agaatggctg tttgagggta
     3841 atctttaccg ttgtcggatc gatcgcttcc gttttggcga tattcttata caggttatag
     3901 cgtttaagat gattcgccgg atcgctggcc cggtccagat tcgctttcac cgccgctgcg
     3961 ttgaaatcgg tgccatcctg gaatttaatg ccttcccgca atttcacggt gtaagtaagg
     4021 ccgtcatcgg aaacggtgta actctccgcc agcacgtttt tcagtttcat ctctttatcc
     4081 agaccgaaca gcccctggta aaacgatttc gctacggcct gagataacgt gtcatttgcg
     4141 tcatacggat cgagcgtggt gaagttcgat cccaccgcca ccaccacctc tttggcagcg
     4201 aatgcacaag atgccatcaa cgctgtcgca atgcccagcg ccactaaccc actacggtgt
     4261 acagctcttg ccattttatt ctccgcctga atgttatcta cgcatgaatg cgtattctga
     4321 ttgtggttgt gcgacgtaat gccccggccc gacgcattgc aacgagacgg ctgcaacctc
     4381 ttcgccacgc agatgaatat tgctgggaag atcgtccgac agcagtacac gctgcggtcg
     4441 ttgtcgggac ggttcagcga ccggaactgc cgccagtaat ttacgcgtat aaggatgctg
     4501 cggattttca aagaccgcgc gccgtggacc aatttcaaca atttgcccga gatacatcac
     4561 cgccacacga tgactaatcc gctcaaccac ggccatatcg tgggagataa acagatacgc
     4621 aatgccgaaa tcacgctgga gatcgagcaa caagttgata atctgcccgc gaatagaaac
     4681 atccagcgcc gagacggctt cgtcggcaat gatcactttt ggattcaatg ccaacgcgcg
     4741 agcaatgcag atgcgctggc gctgaccgcc ggaaaactca tgtgggtaac gccaggcatg
     4801 ttccggtaac aggcccacgc gctccagcaa ccacgcaacg cgtgcagccg cttctttacc
     4861 tggcaataaa ccgtgtacgc gcagcggttc gagaatcgaa tcaccgatag tctgacgtgg
     4921 gtccagcgaa gcgtaagggt cctgaaaaat aaactgaata tcgcggcgca atgcctgaag
     4981 tttaccgggt gacaaggtat cgattcgctg accgttaaag ataatttcgc cgccctgcga
     5041 ttcgaccagg cgcaacaacg cccgcccggt agtggattta ccgctgccag actcgcccac
     5101 cagcgatagc gtttcgccag gccagagatc aaaactgact ttctcaacgg catgcacttc
     5161 ccgcgttacg cgattcaaca aaccgctgcg caaagggaaa cgggtgacca gattacgcac
     5221 ccgtaaaaca ggttcgccat ccaccaccgt tttctgctcg atggatgact cctgtttcgc
     5281 tggatgttca agcgatatca atgggaaacg tcggggataa tctaaccctt tcatcgcacc
     5341 aagttgcgga acagcagcta acagcgcacg ggtataagga tgttgcggtg catgaaaaat
     5401 ctgttcgacg ctacccgttt ccaccgcctc gccctgatac atcaccagta cccgatcggc
     5461 aatctctgcc accacaccca tatcgtgagt gataaagata acgcccatcg acatctcttt
     5521 ttgcaatact ttgattaatt gcaggatctg cgcctgaata gtgacatcca gcgcggtggt
     5581 tggctcatcg gcaatcagca ccgccgggcg gcatgacagc gccatcgcaa tcatcactcg
     5641 ctggcgcatc ccgccagaga gttgatgcgg ataacgtgaa agaatggttt gtgcctccgg
     5701 aatgcgtacc tgatccagca tccgcttcgc ctcgaccatc gcttcttcac gactggcgtt
     5761 ctgatgcaga cgaatagatt cagcaatctg ttcacccaca gtaaataccg ggttcagcga
     5821 tgtcatcggc tcctgaaata tcatcgccat atccgcaccg cgcacatggc gcatttgtgc
     5881 agcgctctgc tcgctaagtt caattacttc gcgactgcgc cgctgcaaca gcattttatc
     5941 gcactgcact aaaccgcccg cctgttccaa caggcgcatc aatgccagcg cagtcactga
     6001 cttaccggag ccggattcgc caacaattgc cagcgtctca ccacgttgca ggctaaaaga
     6061 gagattgcgg accgcagcta ttttctgctg ctcctgcata aaggcaatat tcagattttc
     6121 aaccgccagc acatcaccgg catcaagttc atcactgtgt ggcaacggtg tccccttttt
     6181 cacggtagat accggtggtt ggcgtatcgc ctgcgtagcc ccaggcgcga tacattcctt
     6241 cggtgttaaa cggtagcgcg acattccctt catggtcgat agcgattaag ccaccgctac
     6301 cgccaagcgc agggagtttt tccattacta cccgctcgca ggcttccgcg agacttaatc
     6361 cgccgtaatc cattaacgcg gcgatatcat atgccgccag cgcgcggatg aagacttcgc
     6421 ccgtaccggt acaggaaacc gccacactgg cgttattggc atagcatccg gcccccacta
     6481 agggactatc gccaactcgt ccgggtaatt tattggtcat tccgcccgtg gacgtggctg
     6541 ccgccagatt gccgtctaaa tccaacgcca cggcccctac ggtgcccatt ttctgttttt
     6601 catccagtgg cgcaccgcta tggtcgagga ctgttgcccc ttcctcgcgc gctgccatta
     6661 gttgttcata acgcaaaggt gtggagaaaa tctccggcga gacgcgctcc atgccatgag
     6721 caaacgcaaa attttctgcc ccttcgccaa tcatcatcac atgcgggctt tgctccatca
     6781 ccagccgggc ggcaagaacc ggattacgca gatgactaac gcccgccacc gcaccggctt
     6841 tcagggtgtt accatccatc agacaggcgt ccagttcatg ggtttcatca cgcgtaaaga
     6901 cagcgccaat tccggcgtta aacagtggac actcttccag cagacgcacc gcttccgtca
     6961 ccacatccag cgcactttcg cccgctacca gcattttctg cccggtttca acaatggcag
     7021 acaacgcctc gatgtagcgt aattcctgtt gcagactcat ctgcgcgcgg ctaattgcac
     7081 ctgcgccacc atgaattgca atgactgctt tgcccatagt attcgtccat taagagtggc
     7141 tcgccacttt tgctataaat atcagaattt ttatgaatga ctcattcaat ttttgaatat
     7201 agaaagatgg atatggcatg taaaggcagg agccagcgct acgcccgagg tggcatacag
     7261 tctgtggcgt ttttctgaca taataggcaa attcgatttt gcctccgcag gagtgttttc
     7321 atggaattta ccaccggatt gatgtcgctc gacaccgcgc ttaatgagat gctttctcgc
     7381 gttaccccac tgaccgccca ggaaacgctg ccactggttc agtgttttgg ccgtattctg
     7441 gcgagcgatg tcgtttcgcc actggatgtc ccggggtttg ataactccgc tatggacggc
     7501 tacgcggtgc gtttagccga tattgcctcc gggcaaccgc tgcccgttgc tggtaaatcc
     7561 tttgccggtc agccgtacca tggtgaatgg cctgcgggta cctgcattcg tattatgacc
     7621 ggtgcgccgg tgccggaagg ctgcgaagcg gtggtgatgc aggagcagac tgaacaaacg
     7681 gacaatggcg tgcgttttac tgctgaagcg cgtagcgggc aaaatattcg ccgtcgcggt
     7741 gaagatatct ctgcaggtgc ggttgttttc ccggcgggga ctcgcctgac taccgctgaa
     7801 ctgccagtga ttgcttcgct agggattgcc gaagttccgg tgattcgtaa agtgcgtgta
     7861 gcgctttttt ctaccggtga tgaactccag ttgcccggtc agccgctggg cgacggccaa
     7921 atctacgata ccaaccgtct cgccgtacac ctgatgttag aacagttggg atgcgaggta
     7981 atcaacttag ggattatccg cgacgatccc catgccctgc gcgccgcatt tattgaagcc
     8041 gacagccagg cggatgtggt gatcagttcc ggcggtgttt cagtgggtga agcggattac
     8101 accaaaacga ttcttgaaga gctgggggag atcgccttct ggaaactggc gattaaaccg
     8161 ggtaaaccgt tcgcgttcgg taaactttct aatagttggt tctgcggcct gccgggcaac
     8221 ccggtttcag cgacgctgac cttctatcaa ctggtacagc ctttgctggc aaaactaagc
     8281 ggcaataccg ccagcggcct gcccgcgcgc cagcgtgtac gcacggcatc gcctctgaag
     8341 aaatcgccag gacgccttga tttccagcgc ggcgtgctgc aacgcaacgc cgatggcgaa
     8401 ctggaagtga cgaccaccgg acatcagggt tcacatatat ttagctcctt tagcctcggc
     8461 aactgcttta tcgtgctgga acgcgatcgc ggcaatgtgg aagtgggcga atgggtggaa
     8521 gtagaaccgt ttaacgcgtt gttcggaggc ctgtaatggc ggaactcagc gatcaggaga
     8581 tgctgcgcta caaccggcaa atcattctgc gcggttttga ttttgacggt caggaagcat
     8641 tgaaagattc tcgcgtgctg gtcgtcggcc ttggtggact cggctgcgca gcttcgcagt
     8701 atctggcaag cgccggtgtc ggcaacctga cgctgctcga cttcgacacg gtttcgctct
     8761 ccaatctgca acgccagacg ctgcacagtg atgccacggt cgggcaacca aaggtggaat
     8821 ccgcccgtga cgccctgacg cggatcaacc cacatatcgc gattacgcca gtcaatgcgc
     8881 tgcttgatga cgctgaactt gctgcgatga ttgcaaaaca cgatctggtg ctcgactgta
     8941 cggataacgt tgcagtacgt aatcaactga acgcaggctg ttttgccgcg aaggtgccgc
     9001 tggtttccgg cgcggcaatt cgtatggaag ggcaaatcac ggtcttcact tatcaggacg
     9061 gcgaaccgtg ctatcgctgc cttagccgtt tgtttggcga gaacgcgtta acctgcgtag
     9121 aagcaggcgt gatggcaccg ttaatcggcg taattggttc gttgcaggca atggaagcga
     9181 tcaaactgct ggcaggttat ggcaaaccag ccagcgggaa aatcgtgatg tacgatgcga
     9241 tgacctgtca gtttcgcgaa atgaaactga tgcgcaatcc ggggtgtgag gtgtgcgggc
     9301 agtaactgcc acctccaggc cagataagac gcggcactcc gccacgtcat cagcaattta
     9361 tgaggatgca gaacgtccgg ttaaatcgac gttctgccaa acgctccctg ccagtcctgc
     9421 tcaaacttcg ccacagcggc atcaaccgcc ggatagctaa tcatctgttg tgccacatcc
     9481 agtggcagag taattgattc acaccctgcc agtaagcagt ccagcgcctg acgcggggtt
     9541 ttgaaactcg cggctaacac tttcgcctgc ggcgcatgca ttttcaataa ctggtgtaag
     9601 tcggtcacag tctgaatacc gctaccgccc tgagcatcaa tacgattaac gtaaggcgca
     9661 acatattccg cacctgccag cgccgacagt agcccttgtg ctgcgccata taccgcggtt
     9721 cccagcgtcg gaatcccttc cgcttttaac atcttaatag ctgccagccc ctctgcggtc
     9781 accggaactt tcaccacgat atccgcaata atagaacgca atttacgtgc gtcattcacc
     9841 atcccttcag cagtggtagc cattacctgg gcaaacagac gcccctgacc gcccatcgcc
     9901 tcgtgaagtt gcggaagcac aacctccagc ggttttttac ccactgcgat aatgcttggg
     9961 ttagtggtta cacccgccag cggaaaaata cgtgacagcg ccttcaccgc aacaacgtct
    10021 gaagtatcca gatacagttc cataaccatc ctcaaaatgt actttttgtc tgaatgtaga
    10081 ctatcacggg aaaactctct gaacagttga cgcacatcaa tccaactttc attcgaaagt
    10141 attttaatgt ttgaacgaaa cagagaggca actatgattt tcaatattca acgctactcg
    10201 acccatgatg gccccggtat ccgcacggtc gtatttctta aaggctgttc gctgggctgc
    10261 cgctggtgtc agaacccgga aagccgcgcc cgcacgcagg atctgctgta tgacccacga
    10321 ctctgtctgg aaggctgtga gctgtgcgct aagaccgcac cggaagtgat tgagcgcgcg
    10381 ttgaatggtt tgcttattca tcgggaaaag ttaaccccgg agcattttac ggcgctaacc
    10441 gactgctgcc cgacacaggc gttaaccgtg tgtggtgaag tgaaaagcgt tgaggagatc
    10501 atggcaaccg ttttgcgcga taaaccgttt tacgatcgca gcggcggcgg cttaacactt
    10561 tctggcggag aaccctttat gcagccggaa atggcgacag cgctactgca agccagccac
    10621 gaagccggta ttcatactgc ggtagaaacc tgtctgcatg tgccgtggaa atatatcgcc
    10681 ccttctctgt cctatattga tctgtttctt gccgatttaa aacacgttgc cgacgcgccg
    10741 tttaaacagt ggaccgacgg taacgccgcc agggtgctgg ataatctgaa aaaactcgcc
    10801 gcagcgggca aaaaaatcat tatccgcgtg ccactgattc agggctttaa tgccgacgaa
    10861 acctctgtga aagccattac cgattttgcc gccgacgagc tgcacgttag cgaaattcat
    10921 ttcctgccct accacacgct gggcatcaac aaatatcact tacttaatct gccctatgac
    10981 gccccggaaa aaccgcttga tgcgccagaa ctgctcgact ttgcccagca gtatgcctgc
    11041 cagaaagggt taaccgcgac cttacgagga taacaaccat gaccacactg aaactggaca
    11101 cgctcagcga tcgcattaaa gcgcacaaaa atgcgctggt gcatattgtg aaaccgccgg
    11161 tctgtaccga gcgcgcgcag cactataccg agatgtatca acaacatctc gataagccga
    11221 tcccggtacg tcgcgcgctg gcactggcgc atcacctggc gaatcgcacc atctggatca
    11281 aacatgatga attgatcatt ggcaaccagg caagcgaagt tcgcgccgcg ccgatcttcc
    11341 cggaatatac cgtctcctgg atcgaaaaag agattgatga tctggcagat cgtcccggtg
    11401 ctggttttgc ggtgagtgaa gagaacaaac gcgttctgca tgaagtgtgc ccgtggtggc
    11461 gcggtcagac cgtacaggat cgctgctacg gcatgtttac cgatgagcaa aaaggtctgc
    11521 tggcgaccgg catcattaaa gcggagggca atatgacctc cggcgatgcg cacctggcgg
    11581 tcaatttccc gctactgctg gaaaaaggtc ttgatggtct gcgtgagaaa gtggcggaac
    11641 gtcgctcgcg catcaatctg acggttctgg aagatctgca cggcgagcaa ttcctgaaag
    11701 cgattgatat cgtgctggtg gcagtcagtg aacacattga acgtttcgct gccctggcgc
    11761 gtgaaatggc cgcgaccgaa acccgcgaaa gccgtcgcga tgaactgctg acgatagcag
    11821 aaaactgcga tcttatcgcc caccagccgc cgcagacttt ctggcaggcg ctgcaactgt
    11881 gttacttcat ccagttgatt ttgcagattg aatctaacgg tcactcggta tcgtttggtc
    11941 gtatggacca gtatctctat ccatactatc gccgtgacgt tgaactgaac cagacactgg
    12001 atcgcgaaca cgccatcgag atgctgcata gctgctggtt gaaattgctg gaagtgaaca
    12061 aaatccgctc cggctcacac tcaaaagcct ctgcgggaag tccgctgtat cagaacgtca
    12121 ccattggcgg gcaaaatctg gttgatggtc aaccgatgga cgcggtaaat ccactctctt
    12181 atgcgatcct cgaatcttgc ggtcgcctgc gttcgactca gcctaacctc agcgtgcgtt
    12241 accatgcggg tatgagtaac gatttcctcg acgcctgtgt tcaggtgatc cgctgcggct
    12301 tcgggatgcc ggcgttcaac aacgacgaaa tcgtcatccc ggaatttatt aaactcggta
    12361 ttgaaccgca ggacgcttac gactacgcag caattggttg tatcgaaacc gccgtcggtg
    12421 gcaaatgggg ctatcgctgt accggcatga gctttatcaa cttcgcccgc gtgatgctgg
    12481 cggcgctgga aggcggtcgt gatgccacca gcggcaaagt gttcctgcca caagaaaaag
    12541 cgttgtcagc gggtaacttc aacaacttcg atgaagtaat ggacgcatgg gatacgcaaa
    12601 tccgttacta cacgcgtaaa tcaatcgaaa tcgaatatgt cgtcgacacc atgctggaag
    12661 agaacgtaca cgatattctc tgctcggcgc tggtcgatga ctgtattgag cgagcgaaaa
    12721 gtattaagca aggcggcgcg aaatatgact gggtttctgg cctgcaggtc ggcattgcta
    12781 acctcggcaa cagcctggcg gcagtgaaga aactggtatt tgaacagggc gcgattggtc
    12841 agcaacagct ggctgccgca ctggcggatg acttcgacgg tctgactcac gagcagctgc
    12901 gtcagcggct gattaacggt gcgcctaagt acggcaacga cgatgatact gtcgatacgc
    12961 tgctggctcg cgcttatcag acctatatcg acgaactaaa acagtaccat aacccacgct
    13021 acggtcgtgg tccggttggc ggcaactatt acgcgggtac gtcgtctatc tccgctaacg
    13081 taccctttgg cgcgcagact atggcaacac cggacgggcg taaagcgcat accccgctgg
    13141 cagaaggcgc tagtccggcc tccggtactg accatctcgg cccaacggcg gtcattggct
    13201 cagtaggtaa actgcctacg gccgcgattc tcggcggcgt gctgctcaac cagaaactga
    13261 atccagcaac gctggagaac gaatctgaca agcagaaact gatgatcctg ctgcgcacct
    13321 tctttgaagt gcataaaggc tggcatattc agtacaacat cgtttcccgc gagacgctgc
    13381 tggaggcgaa aaaacatccg gatcagtatc gcgatctggt agtgcgcgtc gcgggctatt
    13441 ccgccttctt caccgcgctc tctccagacg ctcaggacga tatcatcgcc cgtactgaac
    13501 atatgctgta atcttctcag cccggcggcg gcgtcgccgg gctaaatcat tcacatcatc
    13561 aatttcagcc tcgctttcat tcgaaatata atttgtgctc tgcgtcacat tgttattaca
    13621 ctgttacggt ttcattttcg agccaggagc acacctatga gcgtaaaagt tatcgtcaca
    13681 gacatggacg gtacttttct taacgacgcc aaaacgtaca accaaccacg ttttatggcg
    13741 caatatcagg aactgaaaaa gcgcggcatt gagttcgttg tcgccagcgg taatcagtat
    13801 taccagctta tttcgttctt tcctgagcta aaggatgaga tctcttttgt cgcggaaaac
    13861 ggcgcactgg tttacgaaca tggcaagcag ttgttccacg gcgaactgac ccgacatgaa
    13921 tcgcggattg ttattggcga gttgctaaaa gataagcaac tcaattttgt cgcctgcggt
    13981 ctgcaaagtg catatgtcag cgaaaatgcc cccgaagcat tcgtcgcact gatggcaaaa
    14041 cactaccatc gcctgaaacc tgtaaaagat tatcaggaga ttgacgacgt actgttcaag
    14101 ttttcgctca acctgccgga tgaacaaatc ccgttagtga tcgacaaact gcacataacg
    14161 ctggatggca ttatgaaacc cgtcaccagt ggttttggct ttatcgactt gattattccc
    14221 ggtctacata aagcaaacgg tatttcgcgg ttactgaaac gctgggatct gtcaccgcaa
    14281 aatgtggtag cgattggcga cagcggtaac gatgcggaga tgctgaaaat ggcgcgttat
    14341 tcctttgcga tgagcaatgc tgcggaaaac attaaacaaa tcgcccgtta cgctaccgat
    14401 gataataatc atgaaggcgc gctgaatgtg attcaggcgg tgctggaaaa taaaccgccg
    14461 tttaatcttt gattatcacc aattcagttt attgagaaag tgcatgtcat tataccggat
    14521 acggcgtgac cgccttattt ggcatacaaa atcatgaaaa ttcaatatat tgcgatacac
    14581 taccaggcct gataagcgta gcgcaccagg caatcttgcg tttgtcatca gtttcagtag
    14641 ccctgaccat atcagggcta ctgataataa cttactcgat ccctttacta cgcaggtaat
    14701 cttcgtaatt accgctaaag tcgatcacgc gttccggggt gatttccaga atacgggtcg
    14761 ccagggagct tacaaactca cggtcgtgag aaacaaagat cagcgtgccc tgatacagtt
    14821 ccagcgccat gttcagcgac tcaatggatt ccatatccag gtggttggtc ggttcgtcca
    14881 tgatcagaat gttcggcttc tgcatcatta acttaccaaa cagcatccgc cctttttccc
    14941 caccggaaag cactttagct ggctttttga tgtcgtcctg gctgaacagc aaacgaccga
    15001 gaatactgcg caccgcctgc tcgtcatcgc cttcctgctt ccactgactc atccattcga
    15061 acacggtcag atcattttca aactcatatt cgtggtcctg agcgtagtaa ccaatgcgcg
    15121 cgttttcaga ccattttacg gtgccgctgt ccggttgcag atcgcccacc agcgttttca
    15181 gcagcgttga tttaccgacg ccgttggtac ccagtaccgc cagtttttca cccacttcca
    15241 gcagcaggtt gagattttta aacagtggac cgttatcaaa ccctttagtc agaccttcca
    15301 cttctagcgc gttacggaac agtttcttat cctgttcaaa acggatgaac gggttctgac
    15361 ggctggaagc tttcacctct tccagtttga ttttatcaat ctggcgcgcg cgcgaagttg
    15421 cctggcgaga tttcgaggcg ttggcgctaa agcggctaac gaaagattgc aactcagcaa
    15481 tctgcgcttt cttcttcgcg ttatcagcca gcagacgttc acgcgcctga gtcgccgccg
    15541 tcatgtactc atcgtagttg cccggataaa cgcgcagctc gccgtaatcc agatccgcca
    15601 tgtgggtaca aaccatgtta aggaagtgac ggtcgtgcga gatgatgatc atggtgctgt
    15661 cacgctcgtt cagcacctgt tccagccagc gaatggtgtc gatatcgagg ttgttggtcg
    15721 gttcgtcgag caggagaatg tcgggatcag caaacagcgc ctgagccagc agcacacgca
    15781 gcttccagcc aggagcaact tcactcatcg ggccgtagtg ctgttccact ggaattccca
    15841 cgccaagcaa cagttcacca gcgcgagctt ccgcagagta accgtccatt tcgccgtatt
    15901 tcacttccag atcggccact ttatagccgt cttcttcact catttccggc aaagcataga
    15961 tgcggtcacg ctcctgcttc acttcccaca actctttatg ccccatgatc accgtatcca
    16021 gcacagtgaa ctcttcaaag gcaaactgat cctgacgcag cttaccaatg cgttcgttgg
    16081 gatcgaggga aacgttaccc aacgtcggct ctaagtcgcc gccgaggatc ttcataaagg
    16141 tggatttacc actaccgttc gcgccaatca ggccgtaacg gttgccgccg ccgaatttga
    16201 cggaaatgtt ttcaaacaac ggcttactgc cgaactgcat ggtgacgtta ctggaaacta
    16261 acacaggcgt atcctgaaaa gagatatgac aaaccgcgca ttatgccata agtctgaaag
    16321 aagatcctgc tcctcgctta aggtctacac tcaagccaaa ggcaaaaaat gtgatttcgt
    16381 acacatctga tttcactgtg agctggaatg aacttataat gcgcttccag tactctaata
    16441 ttctcaaccc aatggcctgc caggcacaaa atctcgctta acatgaatat gaaattgaaa
    16501 acattattcg cagcggcctt cgctgttgtc ggcttttgca gtaccgcctc tgcggtaact
    16561 tatcctctgc caaccgacgg gagtcgcctg gttggtcaga atcaggtgat caccattcct
    16621 gaaggtaaca ctcagccgct ggagtatttt gccgccgagt accagatggg actttccaat
    16681 atgatggaag cgaacccggg tgtggatacc ttcctgccga aaggcggtac tgtactgaac
    16741 attccgcagc agctgatcct gccggatacc gttcatgaag gcatcgtcat taacagtgca
    16801 gagatgcgtc tgtattacta tccgaaaggg accaacaccg ttatcgtgct gccgatcggc
    16861 attggtcagt taggcaaaga cacgcctatc aactggacca ccaaagttga gcgtaaaaaa
    16921 gcaggcccga cctggacgcc gaccgctaaa atgcacgcag agtaccgcgc tgcgggcgaa
    16981 ccgcttccgg cggtcgttcc ggctggtccg gataacccga tggggctgta tgcactctac
    17041 atcggtcgcc tgtacgctat ccatggcacc aacgccaact tcggtatcgg cctgcgtgta
    17101 agtcatggtt gtgtgcgtct gcgtaacgaa gacatcaaat tcctgttcga gaaagtaccg
    17161 gtcggtaccc gcgtacagtt tattgatgag ccggtaaaag cgaccaccga gccagacggc
    17221 agccgttata ttgaagtcca taacccgctg tctaccaccg aagcccagtt tgaaggtcag
    17281 gaaattgtgc caattaccct gacgaagagc gtgcagacag tgaccggtca gccagatgtt
    17341 gaccaggttg ttctggatga agcgatcaaa aatcgttccg ggatgccggt tcgtctgaat
    17401 taatcttcaa aacgtaaagc aaaggcggac tcataatccg cctttttaat ttgacagacc
    17461 ttatcccgcc gggatcataa ccaacaaaac atatcccacc agcgccgccc acaacagcat
    17521 cggtatcgaa taaagatgaa aacgccacca gatacggcga tcgttcgcca tccgtaacgc
    17581 aatcaaattt gccagcgatc cgggtaataa accaaagcca cctacgttta ccgcccatgc
    17641 cagtaataaa gacggtggca cataattgag cagcaaaatg gtactcggca cgttactgat
    17701 cacctgcgat aaaccgatcg ccgttagcca taatccgggt tcggataaat gactcacgtt
    17761 acttaacacc ccctgcaaaa ctggcagttg ggttagtaaa tggacgtcga taaacatcgc
    17821 cataaacacc agcagcagcg tccagtccac actgagcacc acgcgacgcg ccagcagcgc
    17881 aaagcccgcc gccacaatca ccagtcccca cagctcttgt tttaactcca gcgccgtcag
    17941 aaagacgata tacagcccca gacaactcca caccagccgc ggtttccact ccggcgtttg
    18001 ccctcctgta tggtactgca gcgcctttcc agggaaacaa caccagcaca acagcaggag
    18061 tgtcagcatc attgcgccag ccagcggtgc catttgggca ataaatccgg caaacgaaag
    18121 accagaacgt ccccagataa gaatattttg cgggttgcca attggcgtca gtagcgaacc
    18181 agcattgact gccagcgcct caaaaataat cagccgatta accgggatct cacacagtct
    18241 ttttagcgtg atagtcagcg gaacaactat aaacagcgcg acatcgttgg tcagaaaggt
    18301 agaaagcagc gccgccgcca gtaccataaa catcgccagc cgacgctccg tagcaaaacg
    18361 gcgcaccatt ttgcgcccca gcacatcaaa ataaccgctt aactcgacac ctttagtcag
    18421 cagcatcagg ccgcttaagg tgatgatggt gtgccagtcg atagcagcag gccaggattt
    18481 cggtgcaaag ggaacgaaaa aacttaatcc gatgccaaca agaattaata actgaaaaaa
    18541 acgatcgcct tgcagcgtgc gtaaaaaagg caggctcatt tggcaccgtg tttctgggta
    18601 aacaaacgaa aggcatccag cgtctcttca ctaacatggt gctccatacc ttccgcgtcg
    18661 cgacgggcga tttccggact gacgcccaac accaacaaga aattttcgac tatctgatgt
    18721 cgctcgcggc tttcctgcgc cagcttctct ccttctgccg ttaaaaacac gccacgccag
    18781 gggatcattt caatcagccc catggttgcc agtcgcttaa gcattttagc caccgtcggt
    18841 tgcgaaaccc ccagacgagc agccatgtct acctgacgag cttcccccac ttccctgatc
    18901 aagtcagaaa tcagctcaac ataatcatca ataagctcgc gccgatgcgc ctctctgacc
    18961 tggcggaacc cttcaacgtg ctcttccacg ttcactaact gcgtcacttt ttttgctgtt
    19021 ggcgtacctg cgcgacgact cattatgctt cctcattatg gtgacgcata catagcgttc
    19081 tcatttcgtg cgcacattgt aaaccagagt tgcgaaggta caaaaaatta acgttttagc
    19141 aatagctata taatatagcc tgtgctatat ctgtatgtaa tgcaatcatc cctcaaggat
    19201 cgatgggatt agcaagtcag gaggtcttat gaatgagttc aagaggtgta tgcgcgtgtt
    19261 tagtcattct ccctttaaag tacggttaat gctgctctct atgttgtgcg atatggtcaa
    19321 caacaaaccg cagcaggata aaccttccga taaatagcgg cgtcgcggta cgccgcttca
    19381 ctcctgcttt tatgcaggca caacgcgttt tggtctgaaa aaccccactt tttgtcggat
    19441 ttgcaatccc cttcgcaaaa gatttgttcg tcggtagttg acctgaacag cagctcgctc
    19501 tatcttcttg cagccctgcg tatattgcgg ctcgcggatg cggacccctt tcccctcttc
    19561 acgcactctt gcaggtattg acccttgacg ccagggtaag cacatggcgt ttgttacgat
    19621 agtggcatat gaatttaacc ctcaaagaat cgcttgttac ccgtagccgg gtatttagcc
    19681 cgtggactgc gttctacttt ttacagtcgc tattaattaa cctcggctta ggttacccct
    19741 tcagtttgct ctacaccgct gcgtttacgg ctattttgct tttgctatgg cgaacattgc
    19801 ctcgcgtaca aaaagttctg gtcggtatca gttcgctggt ggcggcttgt tatttccctt
    19861 ttgctcaggc ctacggcgcg cctaacttca atacattgct ggcattgcac tccaccaata
    19921 tggaagagtc gaccgaaatc ctgacgattt ttccgtggta cagctacctg gtcggcatat
    19981 ttatttttgc gctcggcgta atagcaatca ggcgaaaaaa agagagtgaa aaagcgcgct
    20041 ggaatacctt cgacagcctg tgcctggtat tcagtgtggc gacatttttt gttgctcccg
    20101 tgcaaaacct ggcctggggc ggcgtattta aactgaaaga tactggctat ccggtatttc
    20161 gttttgctaa ggatgtcatc gtcaataata acgaggtgat tgaagagcaa gaacggatgg
    20221 caaaactttc cggaatgaaa gatacctgga cggtcactgc cgttaagccg aagtatcaga
    20281 cctatgtggt ggtgatcgga gaaagcgcgc gtcgcgatgc cctcggtgcc tttggcggtc
    20341 actgggacaa taccccgttt gccagcagcg ttaacggttt gatatttgct gactacattg
    20401 ccgccagtgg ctccacgcag aaatcgcttg gcttaacgct caatcgcgtt gtcgatggca
    20461 aaccacagtt tcaggataac tttgtcaccc tggcaaatcg cgcgggcttc cagacctggt
    20521 ggttttccaa ccagggtcaa atcggcgaat acgataccgc catcgccagc atcgccaaac
    20581 gagcagatga agtgtacttc ctgaaagaag gtaattttga agcagataaa aacacgaaag
    20641 acgaagcgtt actggatatg accgctcaag tgctggcgca agagcactcg caaccgcagc
    20701 tgattgttct acatctgatg ggctcgcatc cgcaggcctg cgaccggaca caaggaaaat
    20761 acgaaacctt tgtgcaatcg aaagaaacgt cgtgctatct ctataccatg acgcaaacag
    20821 acgatttact gcgcaagctg tacgatcagt tacgcaacag cggcagcagc ttctcgctgg
    20881 tttacttttc tgaccacggt ctggccttta aagagcgcgg caaagacgtg caataccttg
    20941 ctcatgatga taagtatcag caaaatttcc aggtgccttt tatggtcatt tccagcgacg
    21001 ataaagcgca tcgggtgatt aaagcccgcc gctcggccaa tgacttctta ggctttttct
    21061 cgcagtggac gggaattaaa gcgaaggaaa taaatatcaa atacccgttt atatctgaaa
    21121 agaaagccgg gccgatatac atcaccaact tccagttaca gaaggtggat tacaaccatc
    21181 tcggaaccga tattttcgac ccgaaacctt aaaacaaaaa aatccgcccc gagaggcgga
    21241 tttttatatc accgaagtga ttagaagcgg taaccaacac cggcaatcca ggtgcctacg
    21301 tcaacgctac gaatacggct ctgctcgtaa gagaagtcca gagcaacgtt ttccatcggg
    21361 ttgaactgca gaccagcacc gtaggagaaa ccgtagtcgc tggtgtcgtg tttgtaggtc
    21421 gggtattcag tggtctggaa tttaccataa cccacaccca ctacaccgta gatgcttgcc
    21481 cagtcgttaa tgcggtaagc cggaccagca gtgatgccgt agtactggtt tttgttgtag
    21541 tcaccagagc ttgcagtacg gcttttctcg gtgtaagtga aagaaccgat cacacccagc
    21601 gggctgttgt cttcttcata gcggtatttc aggttgaaac cgcccatttt gttcatttgg
    21661 ccctgagcgt cgctctgtgc gtaaccgcca gttacagtag aagtcgcagc tacggaagta
    21721 cctgcggtga aagccagaac tgcggccagt gctgaaagac atgcaatttt tttcataacc
    21781 acctcaaatg tgattcaaat aagtcctaag ttttaaatat atcaaaaatt aatgggaaac
    21841 tcttcgcgat ttatgatgtc taacgggcca tttcatgtaa cagaacgttt ccatacaccg
    21901 ctatccatct aaatttaaat cactttttca gagaactgcg taagtattac gcatattttc
    21961 cctgtcattc atccagatta ttcctaatca ccagactaat gattccatca atcctggcgc
    22021 attttagtca aaacggggga aaattttttc aacaaatgct caaccagcat tgggtatatc
    22081 cagtacactc cacgctttac ttaggtttag atatttgtgg gagaaaggat gcctggttca
    22141 ttacgtaaaa tgccggtctg gttaccaata gtcatattgc tcgttgccat ggcgtctatt
    22201 cagggtggag cctcgttagc taagtcactt tttcctctgg tgggcgcacc gggtgtcact
    22261 gcgctgcgtc tggcattagg cacgctgatc ctcatcgcgt tctttaagcc atggcgactg
    22321 cgctttgcca aagagcaacg attaccgctg ttgttttacg gcgtttcgct gggtggaatg
    22381 aattatcttt tttatctttc tattcagacg gtaccgctgg gtattgcggt ggcgctggag
    22441 ttcaccggac cactggcggt ggcactgttc tcttctcgtc gcccggtaga tttcgtctgg
    22501 gttgtgctgg cggttcttgg tctgtggttc ctgctaccgc tggggcaaga cgtttcccat
    22561 gtcgatttaa ccggctgtgc gctggcactg ggggccgggg cttgttgggc tatttacatt
    22621 ttaagtgggc aacgcgcagg agcggaacat ggccctgcga cggtggcaat tggttcgttg
    22681 attgcagcgt taattttcgt cccaattgga gcgcttcagg ctggtgaagc actctggcac
    22741 tggtcggtta ttccattggg gctggctgtc gctattctct cgaccgctct gccttattcg
    22801 ctggaaatga ttgccctcac ccgtttgcca acacgcacat ttggtacgct aatgagcatg
    22861 gaaccggctc tggctgccgt ttccgggatg attttcctcg gagaaacact gacccccata
    22921 cagctgctgg cgctcggcgc tatcatcgcc gcttcaatgg gttctacgct gacagtacgc
    22981 aaagagagca aaataaaaga attagacata aattaaattt acatttctgc atggttatgc
    23041 ataaccatgc agattttctc gctacttttc ctctacaccg tctttatata tcgaattatg
    23101 caaaagcata tttattccga aaattcctgg cgagcaaata aataagaatt gttcttatta
    23161 atatatctaa ctcattgatt tttttattgt ttttgttttt cacgcttgtt accactatta
    23221 gtgtgatagg aacagccaga atagcggaac acatagctgg tgctatactt agtctcgtta
    23281 attactggga cataacatca agaggatatg aaattatgag taccgctaaa ttagttaaat
    23341 caaaagcgac caatctgctt tatacccgca acgatgtctc tgacagcgag aaaaaagcaa
    23401 cagtagagtt gctgaatcgc caggttatcc agtttattga tctttctttg attaccaaac
    23461 aagcgcactg gaacatgcgc ggcgctaact tcattgccgt acatgaaatg ctggatggct
    23521 tccgcactgc actgatcgat catctggata ccatggcaga acgtgcagtg cagctgggcg
    23581 gtgtagctct ggggaccact caagttatca acagcaaaac tccgctgaaa agttacccgc
    23641 tggacatcca caacgttcag gatcacctga aagagctggc tgaccgttac gcaatcgtcg
    23701 ctaatgacgt acgcaaagcg attggcgaag cgaaagatga cgacaccgca gatatcctga
    23761 ccgccgcgtc tcgcgacctg gataaattcc tgtggtttat cgagtctaac atcgaataaa
    23821 tccatcgctg atggtgcaga actttagtac acgataaaag cggcttcctg acaggaggcc
    23881 gttttgtttt gtagcccgcc tcaacgcact tatttagtgc atccatctgc tatccccagc
    23941 tggttaagta aattttttgt atccacatca tcacacaatc gttacataaa gattgttttt
    24001 tcatcaggtt ttacgctaaa taatcactgt gttgagtgca caattttagc gcaccagttt
    24061 ggtgccccag aatggtgcat cttcagggta ttgccctata aatcgtgcat cacgtttttg
    24121 ccgcatctcg aaaaatcaat gagttgcaaa actggcacga ttttttcata tatgtgaatg
    24181 tcacgcaggg gatcgtcccg tggatagaaa aaaggaaatg ctatgaagtc tgtattaaaa
    24241 gtttcactgg ctgcactgac cctggctttt gcggtttctt ctcatgccgc ggataaaaaa
    24301 ttagttgtcg cgacggatac cgccttcgtt ccgtttgaat ttaaacaggg cgataaatac
    24361 gtgggctttg acgttgatct gtgggctgcc atcgctaaag aactgaagct ggattacgaa
    24421 ctgaagccga tggatttcag tgggatcatt ccggcactgc aaaccaaaaa cgtcgatctg
    24481 gcgctggcgg gcattaccat caccgacgag cgtaaaaaag cgatcgattt ctctgacggc
    24541 tactacaaaa gcggcctgtt agtgatggtg aaagctaaca ataacgatgt gaaaagcgtg
    24601 aaagatctcg acgggaaagt ggttgctgtg aagagcggca ctggctccgt tgattacgcg
    24661 aaagcaaaca tcaaaactaa agatctgcgt cagttcccga acatcgataa cgcctatatg
    24721 gaactgggca ccaaccgcgc agacgccgtt ctgcacgata cgccaaacat tctgtacttc
    24781 atcaaaaccg ccggtaacgg tcagttcaaa gcggtaggtg actctctgga agcacagcaa
    24841 tacggtattg cgttcccgaa aggtagcgac gagctgcgtg acaaagtcaa cggcgcgttg
    24901 aaaaccctgc gcgagaacgg aacttacaac gaaatctaca aaaaatggtt cggtactgaa
    24961 ccgaaataat aacgctgcgc ctgtaaagcg cactggcagt tccctctccc cgccggggag
    25021 aggattaggg tgaagggcgc aaacccgctc cggggccatt aattaccctg aatttgatta
    25081 tttacaccac ggtaacagga acaacatatg cagtttgact ggagtgccat ctggcctgcc
    25141 attccgcttc tgattgaagg tgccaaaatg accctgtgga tttcggtcct cggtctggct
    25201 ggcggtctgg tgatcggatt gttggcaggt tttgcacgca ccttcggtgg ttggatagcc
    25261 aaccacgtcg cgctggtctt tattgaagtg atccgcggca cacctatcgt cgtccaggtg
    25321 atgtttatct atttcgccct gccgatggcg tttaacgatt tacgcatcga cccgtttact
    25381 gcggcggtgg tcaccatcat gatcaactcc ggcgcgtaca ttgcggaaat cacgcgtggt
    25441 gcggtgctgt ctattcacaa aggttttcgt gaagcaggac tggcgctcgg tctttcacgt
    25501 tgggaaacca ttcgctacgt cattttaccg ctggcactgc gtcgtatgct gccgccgctg
    25561 ggtaaccagt ggatcatcag cattaaagac acttcgctgt ttattgttat cggcgtggcg
    25621 gaactgaccc gtcaggggca agaaattatt gccggtaact tccgcgccct tgagatctgg
    25681 agcgccgtgg cggtgttcta tctgattatt accctggtgc tgagctttat tctgcgtcgt
    25741 ctggaaagaa ggatgaaaat cctgtgattg aatttaaaaa cgtctccaag cattttggtc
    25801 caacccaggt gctgcacaat atcgatttga acattgctca gggcgaagtc gtggtgatta
    25861 tcgggccgtc cggttccggt aaatcgaccc tgctgcgctg catcaacaaa ctggaagaaa
    25921 tcacctccgg cgatctgatt gtcgatggcc tgaaggttaa cgatccgaaa gttgatgagc
    25981 gcctgattcg ccaggaagcg ggtatggtgt tccagcagtt ttacctcttc ccgcatctga
    26041 cggcgctgga aaacgtcatg tttggcccgc tacgcgtgcg tggcgcgaat aaagaagagg
    26101 cggaaaaact ggcgcgtgag ctgctggcga aagtcggtct ggcagagcgt gcacatcact
    26161 acccttccga actttctggt ggtcaacagc agcgtgtggc gattgcccgc gcgctggcgg
    26221 tgaagccgaa aatgatgctg tttgatgaac cgacttccgc tcttgacccg gaactgcgcc
    26281 atgaagtgct gaaggttatg caggatctgg ctgaagaagg gatgacgatg gtgatcgtga
    26341 cccacgaaat cggttttgcc gagaaagtag cttcgcgcct gatctttatc gacaaaggcc
    26401 ggattgcaga agatggcgat ccgcaggtgt tgatcaagaa cccgccgagc cagcgcttgc
    26461 aggaattttt gcagcacgtc tcttaacttc tctgcctccc tttcccccga aagggaggca
    26521 caccagattc ctctcattta aaattgcctc tcccccagca tctatactta tctttttgct
    26581 ctgttttctc actggaggag tcatgcggtg gatcctgttc atcctcttct gcctgctggg
    26641 cgcacctgcc cacgcggtat ccatacccgg cgttacaacc acaacgacaa cggactcaac
    26701 gactgaaccg gccccggaac cggatatcga acaaaaaaaa gcggcctatg gcgcactggc
    26761 ggatgtgctg gataatgaca cctcgcgtaa agagttgatc gaccagttgc gcaccgtcgc
    26821 cgcgacgccc cctgcggaac cggtaccgaa gatcgtgccg ccgacgctgg ttgaagagca
    26881 aaccgtgctg caaaaggtca ccgaagtcag ccgccattat ggtgaagccc tttccgcccg
    26941 cttcgggcaa ctttatcgca atatcaccgg ctccccgcat aagccgttta atccacaaac
    27001 cttcagcaat gcgctgaccc acttttcaat gttagcggta ttagtgtttg gtttttactg
    27061 gctgattcgt ctgtgcgcac tgccgctgta ttgcaaaatg ggccagtggg cgcggcaaaa
    27121 aaatcgtgag cgcagtaact ggttgcagct tccggcgatg atcatcgggg cgtttattat
    27181 cgacctgctg ttactggcac tgacattatt tgtcggccag gtattaagcg acaacctgaa
    27241 tgcgggcagt cgcaccatcg ctttccaaca aagtttgttt ctcaacgcct ttgccctgat
    27301 tgaatttttc aaaaccgtac tacgcctgat tttttgccca aacgtagctg aactgcgccc
    27361 gttcacgatt catgacgaga ccgcccgtta ctggagtcgt cgcctgagct ggttaagcag
    27421 cctgattggc tatggtctga ttgtggctgt gccgattatc tctaatcagg tgaatgtaca
    27481 gataggtgcg ctggcgaacg tcatcattat gctgtgcatg accgtctggg cgttgtacct
    27541 gatttttcgt aataaaaaag agatcaccca gcatttgctc aactttgcgg agcattcgct
    27601 ggcctttttc agcctgttta tccgcgcctt tgcactggtg tggcactggc tggcaagcgc
    27661 ctattttatc gtgctgtttt tcttttcgtt gttcgatccg ggcaacagcc tgaaatttat
    27721 gatgggtgca acggtgcgca gcctggcgat tattggtatc gcagcatttg tttccggtat
    27781 gttttcccgc tggctggcga aaaccatcac cctctcgcca catactcagc gaaattatcc
    27841 ggagctgcaa aaacggctga atggatggct ttcggcggca ctgaaaacag cgcgtattct
    27901 gacagtctgc gtggcggtaa tgctgctgtt gagcgcatgg ggattgttcg atttctggaa
    27961 ctggctgcaa aacggtgcgg ggcagaaaac cgtagatatc ctgatccgta tcgcactcat
    28021 tcttttcttc tcggcggttg gctggacggt gctcgccagt ttgatagaaa accggctggc
    28081 ttcggatatt catggccgcc cgctacccag cgcccgtacg cgtaccctgc taacgctgtt
    28141 ccgtaacgcg ctggcggtga ttatcagtac catcaccatc atgattgtgt tgtcggaaat
    28201 cggcgtcaat atcgcgccat tgctggcagg tgccggtgca ttgggactgg ctatctcttt
    28261 tggttcgcaa acgctggtga aagatattat caccggggta tttattcagt ttgaaaacgg
    28321 catgaacact ggagatttgg tgactatcgg gccgttgacc ggcactgtgg aacggatgtc
    28381 aattcgctcc gtgggcgtgc gccaggatac cggggcgtat cacatcattc cgtggtcttc
    28441 gataaccacc tttgctaact tcgtccgcgg tattggttcg gtagtggcaa actacgatgt
    28501 tgatcgccat gaagatgctg ataaagccaa tcaggcactg aaagatgcgg tagcagaatt
    28561 gatggaaaac gaagaaattc gcgggctggt tattggtgaa ccgaattttg ccgggattgt
    28621 cggcttaagc aataccgcgt ttacactgcg tgtttcgttc accacgctgc cactcaaaca
    28681 gtggacggta cgctttgccc tcgacagcca ggtgaaaaaa catttcgacc tggcgggtgt
    28741 tcgcgcgccg gtgcagactt atcaggtgct gccagctccg ggcgcggccc cggctgaacc
    28801 gttgccgccg ggggagccaa cgctttaacg ctggcgattg acaaaacggc ggcgctgctc
    28861 gtcgttcata aaggtccagg ctataaagcg gctctgcttt tgcccctggg ccatctcttt
    28921 ttttaccacc ttcaccgcac ctacgtccgt caaagcacga tacaacggcg gtaagttttc
    28981 accacgagat accagcgagg taaaccacat cacctgcttc gcgaagcctt tgctctcttc
    29041 aatcatcttt ttgataaaag cgacctcacc gccttcacac cacaactcct gttgctgacc
    29101 accaaagttc agtgcatcgt ctttgttcag ccccaggtta cggcgtttac gttcactacc
    29161 tgcccgtgcc gcagcggcgg aatcgtggaa tggcgggtta cacaaggtcg catcgtattg
    29221 ctcgttttta tggatgatgc cgttaaaaat cgccccactc tctttttgcc gacgcagacg
    29281 aatggcgcgg ttaagccccg gattagcact gatgatcgcc tgcgcactgc ttaacgcctg
    29341 gctgctggtt tcactaccgg taaaacgcca gccatattca tgtacgccaa tcagcggata
    29401 aatacagttc gcaccaacgc cgatatccag aatgctggca ttagctggaa ttgttccgct
    29461 tgcttcggcc agtaaatcgg caaggtgatg aatataatcc gcccggcccg gtactggtgg
    29521 gcagagaaaa ccgtccggga tatcccagtt cgctacggcg taaaaatggg ccagcaacgc
    29581 cttattgagc gccttcaccg ccagcggatt ggcaaagtct acgctttgct ccccggcggg
    29641 tgtaagcgtg aggaattgcc tgagttcagg attgacctga caaagcgtgg cgagatcgta
    29701 gcggctgtga tgacggttgc gcggatgcaa ccccggtttc tgggcggaca tagcattctc
    29761 ctttaagcag cggcgtaaga tacccgcata acgcgacagg gtaaatatct ggctgcgttt
    29821 atcatttcta aaaaccttca catggctatg gtttatggca attcaccata aaaaacatca
    29881 tcatgcatgt cattgatttg tcttattttg taaaaacaca tcgttcaaaa aataagcgca
    29941 tctctgtcaa ttttttgcgt cattttcatc gcgcaggcga cctacactta tctggcacta
    30001 cccgttgtat ttatgaggat gtcattatga aaaagtgcct cacactactg attgccaccg
    30061 tcctgagcgg aatctctctc acggcttatg ccgcgcaacc gatgagtaac ctggacagtg
    30121 gtcaactacg gcccgccggt accgtttcgg caactggcgc atcaaaccta agcgatctgg
    30181 aggataaact ggcagaaaaa gcgcgcgaac aaggcgcgaa aggttatgtc attaattccg
    30241 caggcggaaa tgaccagatg ttcggtactg caatcatcta caaataaccc caccaacgta
    30301 actgcattcg cctctggatg cagttttcgt ccaatttgta agcaaaaaac atcaaatatg
    30361 aacgcaatgt aaataaatgt atttcttttt cgcgcaatgg gtgatagaaa atcgcgccaa
    30421 gtgataatgc ttatcaatat tattatcact tgcacgtacg ctatcacggg attaacagtg
    30481 gcatcgcatc cgcagagatg ctttctcgtg acagtgaaaa tttcaccata taagaaaaag
    30541 tcacctgcaa aatggaaaac aatcgcaatt tccctgccag acaatttcat tcgctcacgt
    30601 tctttgccgg tctttgtatt ggtattacgc ctgtggcaca ggcactcgct gccgaagggc
    30661 aagctaacgc ggatgacacg ctggttgtcg aagcatcaac gccttcgctt tatgcgccac
    30721 aaaaatctgc cgatccgaaa ttctcgcgtc cggtagcgga tactacccgc acgatgacag
    30781 tgatttctga acaagtgatt aaagatcagg gtgcaaccaa ccttaccgac gcgctcaaaa
    30841 acgtccccgg cgtgggtgcg ttttttgcgg gtgagaacgg taactccacc actggcgacg
    30901 ccatttatat gcgcggtgcc gatacctcta acagtattta tatcgatggc attcgcgata
    30961 tcggcagcgt ctcgcgcgac accttcaata ccgagcaggt cgaagtaatt aaagggccgt
    31021 ccggcaccga ctacgggcgc agcgcaccga caggctcgat caatatgatc agcaaacagc
    31081 cgcgcaatga ttccggcatt gacgcctccg ccagtattgg cagcgcctgg ttccgccgcg
    31141 gcacgctgga cgtcaatcag gtcattggtg ataccactgc ggtgcgcctg aatgtaatgg
    31201 gcgaaaaaac gcacgatgcc ggacgcgaca aagtcaaaaa tgagcgttac ggcgtcgccc
    31261 cttctgtcgc ttttggcctt ggtacagcga atcgtttgta tcttaattat ctgcatgtca
    31321 cccagcacaa cacgccagac ggcggcattc cgaccatcgg tttaccgggt ttttctgccc
    31381 catctgcggg aacagcggcc ctgaatcatt ccggaaaagt tgatacgcat aacttttacg
    31441 gcacggattc cgattacgac gattcgacca ccgacaccgc taccatgcgt tttgagcacg
    31501 acatcaacga taacaccacc attcgcaaca ctacgcgttg gtcgcgcgta aagcaggatt
    31561 acctgatgac ggcgattatg ggtggagcgt cgaatattac ccagcccacc agcgatgtga
    31621 atagctggac gtggtcacgc acggcgaata ccaaagatgt gagtaacaaa attctcacca
    31681 accagaccaa cctgacctcg acgttctata ccggcgctat cggtcatgat gtcagtaccg
    31741 gcgtggaatt tacccgcgaa acacagacta actatggcgt taatccggtg acgttaccga
    31801 cggtaaatat ttatcatcct gacagcagca ttcatcccgg cggcctgacg cgcaacggcg
    31861 caaacgccaa tggtcagacg gataccttcg caatttatgc cttcgatacg ctgcaaatca
    31921 cccgtgattt tgagctgaac ggtgggatcc gtctggataa ttatcatact gaatatgaca
    31981 gtgccaccgc ctgcggcggc agcgggcgcg gtgccatcac ctgccctgct ggcgtggcaa
    32041 aaggttctcc ggtaaccacc gtcgacaccg ccaagtcggg caatctggtg aactggaaag
    32101 ccggggcgct gtatcacctg acggaaaacg gcaatgttta tattaactat gccgtttccc
    32161 agcagccgcc gggcggcaac aacttcgccc ttgcgcagtc tggcagcggt aacagtgcca
    32221 accgcaccga ttttaaaccg caaaaagcca acaccagcga gattggcacc aaatggcagg
    32281 ttctggataa acgcctgcta cttaccgccg cgctgttccg tactgatatt gaaaatgaag
    32341 ttgagcaaaa tgatgatggg acttattcgc aatatggtaa gaaacgtgtc gaaggctatg
    32401 agatatccgt ggccgggaat atcacccccg cgtggcagat gattggcggc tatacccagc
    32461 aaaaagcaac tatcaaaaac ggcaaagatg ttgcccagga tggttcctca tcgctgccgt
    32521 ataccccgga acacgccttc accttatgga gccagtatca ggcaaccgat gatatttctg
    32581 ttggtgcggg cgcacggtat atcggcagta tgcataaagg ttcagacggc gcggtgggaa
    32641 cgccagcatt taccgaaggt tattgggtcg ccgacgccaa actggggtat cgggttaatc
    32701 gcaatctcga cttccagcta aacgtctaca acctgtttga taccgattac gtcgcctcaa
    32761 tcaataagag cggctaccgt tatcacccgg gcgagccaag aaccttcttg ctcacagcca
    32821 atatgcattt ctgattcaga tgtggggcgc aggccccact ttttggagaa cttgtatgat
    32881 gtaccacatt cccggcgtgt tatcgccaca ggacgtcgcc cgttttcgcg aacacctgga
    32941 acaagccgaa tgggtggatg gacgcgtcac caccggcgca caaggtgcgc aagttaagaa
    33001 caatcaacaa gtagacaccc gcagcgccct gtacgccgcc ctgcaaaatg aggtgctgaa
    33061 cgcggttaac caacatgctt tgttctttgc cgcggccttg ccgcgtaccc tttccacgcc
    33121 gctgtttaat cgctatcaga acaatgaaac ctatggtttt catgtggatg gcgcagtacg
    33181 cagccatcca caaaacggct ggatgcgcac tgacctttct gccacgctgt ttttaagcga
    33241 tccagaaagc tacgacggcg gcgaactggt cgttaatgac accttcgggc aacatcgggt
    33301 aaaactcccg gcaggcgatc tggtgttgta tccctccagc agcctgcatt gcgtgacacc
    33361 cgtaacccgc ggcgtgcgag tggcatcatt tatgtggatc cagtcgatga tccgcgatga
    33421 taaaaagcgc gccatgctgt ttgaactgga caacaatatt cagtcgctga aaagccacta
    33481 cggcgaaagt gaagagatcc tgtcgctgct caatctttat cataatctgc tgcgggaatg
    33541 gtcggagatc tgacgcttga actgcccgag ttcgtcccta tattagctac acttaactgt
    33601 acaagcattg atatggggag gacgatatgg catccggttg ggctaatgat gacgccgtca
    33661 acgaacagat caacagtaca attgaagatg cgattgcccg cgctcggggt gaaattccgc
    33721 gtggcgaaag cctgtatgaa tgtgaagagt gcggtgcccc tatcccgcag gcccgtcggg
    33781 aagccattcc tggcgtgcgc ttatgcattc attgtcagca ggagaaagat ttacaaaaac
    33841 cagcttatac aggatataat cgcagaggtt cgaaagacag ccagttacgt taactacaac
    33901 tggcgggatg tatagcgaat ataatttgta ttttgcgtgg cattccgtgc ctttaacgct
    33961 accgtgactg ccacgcggta taaaacaagt ccataagtac aacaaataaa tggtttatca
    34021 gtatgttaga tatcaatcaa tttatttgaa caaggtggtc aattctcttc gattttatct
    34081 ctcgtaaaaa aacgtgatac tcatcacatc gacgaaacaa cgtcacttat acaaaaatca
    34141 cctgcgagag attaattatg aaaactatca atactgttgt tgctgctatg gctctttcaa
    34201 ctctgtcatt tggcgtgttc gcggcggaac cggtaacggc atcccaggca cagaacatga
    34261 ataaaatcgg cgtggtttct gccgatggcg catccaccct cgatgccctg gaagcgaaac
    34321 tggctgagaa agccgcggcg gccggtgcca gtggatacag catcacttct gccaccaaca
    34381 acaataaatt aagcggtact gcggtaattt ataagtaatt cgtaagctgg atcaggcgtt
    34441 tacgctacgt tcagcacaag tatttccctg tctgtttgcc gacagacgca tatgctctaa
    34501 ccctcatgat cctatgttac ccttgtttgc ccgtccgcca ctggacgggc tttttttagc
    34561 tggctagctg ctgacagaaa gcctgcaacg tctcttccgg cataccaatc tgccgcgccg
    34621 catcacaaat ggcctgccag cttcccgcat ccagtggaat cccctgctcc tgccgttcgc
    34681 gacgcgtgtt cacttcccac tcgcccggta gcaaaatcgg cttatcgtca tcatgcggcg
    34741 aggctttcac ccactcggca aaggcttcgg tctgcgcact acaatccggc gcgccgaaca
    34801 gttccgggtt gataatgata gtggtcatgc agttaagaat ggcatcggga ctggtttgta
    34861 acgtttcctg atgcgtcgtt ttaccgccag aaagcgcccc gccaagaatt tcacacatcg
    34921 ctgcaagggc gtagccttta tgttcggcaa aggtcaacag cgaacccaac ggcgactcct
    34981 gcattaccgc cggatttgtc gtcggcacgc cgttaacgtc aatcaggcaa cctggcggca
    35041 cggggacgcc tttatgccag gcgacgcggg ttttgccaaa tgcaatggcg ctggtggcgt
    35101 aatcgagcaa cagcgggaaa ttatctttac gagggaaaac cacacagaac ggattggtgc
    35161 caaagcggct gtcgcgaccg tggaacggcg cgaccattgg aataccgacc acgctaacaa
    35221 agtggataga gacaaacccc gccgctgcac actgctccgc ccagtaaccg atacggccga
    35281 tatgatgcga gttatgtagc gccacggcgg caatgccgtg ctgatgcgct ttctcaatcc
    35341 ccagcgccat cgcttcgtgt gccgcgacct gaccaaatgc gcgatcgcca tcgagcgtga
    35401 ccgccgcccc cgcttcttta acgactttgg catgatggtt aatttgcaga tgcccctgac
    35461 tccaggagcg cacatagctt gggatcatgc caataccatg tgaatcatgc cctgccaggt
    35521 ttgccgcgat caaatgatcg gcgactaatt tcgcttcctg ttcctcacta cccatctgac
    35581 gaaatacagc ctgaataaaa ctgtgcagcg tctgagcatc aaagcgatgg ccactttcca
    35641 tggttaactc ctgtttatgt tatgtgtttg ttgtttttta tgctgcacgc cgggcgcggg
    35701 aaggtcaata aagatgcagg aatttcatat tgcggtgggg taaaagccgg atgacatggc
    35761 tcatccggct gagataaaaa ttaaaatgcc tgattaacgc gcgccaggcc gtcgctgata
    35821 gttgccgctt cacccgtagc catcaggcag caagccatct ggattttcag cgattcggga
    35881 atcggttcgc tgccagccag gcaacgctca atccactgcg ccgtggtttc cggatctttt
    35941 gcttgtggca gtaactcgct accagcagtg tcctgttttt catacagtac ccgcatccct
    36001 tcacggtcaa tgagattgat ctgcgggcag cgctgcggat tagcatacac ttcaccttca
    36061 gtaccatgca taagtagcgc ccgcccgccg atatcgctaa agaacttcgc gacgcgtcca
    36121 atgtattccg gatgcgaaac gctggaaaga cgcagtgcct caccttcggc aaatggcgtc
    36181 gccagtttcg ccagggtatg tgcactgtta cgcacgccca tccgccagcg catcgccagt
    36241 tgtttttcca gcggcgggca aaacgcgccg acaggcataa agacaggttg atgttcgtcg
    36301 agcttcgcct gcgcctgccc gccgtgcaac gttggcgtaa tacccatcag ttcgaaaatg
    36361 gtttcggtca gcacgcgggt tggatcttcg ctaaccccgt gaaccaccac aggaaaaccg
    36421 agtttgtgca gcagaatcgc cagcaacggc gtcaggttgg cctgtttacg cgcgccgttg
    36481 taactgggga tgacaatcgg catcggcttg cctgcaggcg gcgtcagctt gatggtgtga
    36541 ttttgcatgg cttcgtaaaa gccgagcatc tctgcttccc cttccccttt gatacgtagc
    36601 gcaatcaata cgccgcccaa ctcaaggtca gggacttcac cattgagcat atgggcatac
    36661 agaccgcgcg cagtatcccg gtctaaatcg cgcgcgtggt ttttcccgcg cccgatctct
    36721 ttaatgattt tgcgatagtc catttacgac tccttacctg actcacatca ttaacgccgc
    36781 cgacggcgtg gggatttcgt tttttctttc tttttaacta taccttcagg gacttccggt
    36841 tgctctatcg gaaataccgg taatgcatcc agtagtcgct tgccataatt ttttgtcagc
    36901 aagcgtttgt cgtagataac cacttccccc cagcaaccgt ggcttcgaat cagtcgccca
    36961 acctgctgaa tcaggttaaa cgaagcgctc ggcaggcttt gcacctcaaa cggatagcgg
    37021 ttaaggcttt tcagccattc accttcggtg atcaccaccg gactgtcgat gggcggaaaa
    37081 gcgattttgt ggatatgcac ctggctgagc agagcgcctt tcagatcaag accttcggca
    37141 aaggactgta agcccaccag cacgctacgc tcaccgttgg caacgcgttt gcggtgcagt
    37201 tcaactaagc gataacgtgg ctgatcgccc tgcaccagca acatcaggcg taaatccgtc
    37261 acatagtcga gaaagcgctg catcgcacgc ccgctggcaa acagcaccaa cataccgaga
    37321 tgttttttgc tctccacctg ctcacggaaa aaggccgcca tttcagcaat gtgctgttct
    37381 tcgttgtcga tggaaggctc aacgcgcatc cggggaataa caattttgcc ctgttcgcag
    37441 tggttaaagg gcgaatccag cgccacaaag cggtcacccg ctttctcttt cagcccactc
    37501 atctcctgca aacgcgaaaa actgttcagc gaacgcaagg ttgcggaggt aacaataatg
    37561 tgcggaatac tgcgccacag cagcctttcc agttggtcgc taacacgaat acccacacag
    37621 tgaaaccaca gatgtagctg cccttcgcgc tcttcccgcg tcgcccattt ggtcaccggc
    37681 gcaccggaag attgcgccag agacgccagc cgccagagtt tgctttgcgc ctcgaacatc
    37741 cccaacgcgc ggttcatctg caaaatcaac cgatgcaggc gtacaatgtc atggctgccg
    37801 gttttctcac ttaaatcgtt aagaaataac tccgccagac cacgcagcat ctcggtgagt
    37861 tttgccagcc gctggcagat ctccagcact tcatcaggca gttcgcccat cgcaaaacgg
    37921 tgctctgcct cctgcccggc aggcatgtag agattgagaa tgttgtttaa cgaggcgata
    37981 agctcataca gctcttcaca atgcgcattc aaacgttcag ggatcgccag cggtgggatg
    38041 gtcttcgggc gaaactgctc catgcaggtg gcgaccagtt tggtgaacag gtccagttgg
    38101 agccggtacc agggcgcagt gatttcggcg ctcatctcca gcgcatcccg cgccacatcc
    38161 ggcaggtgat gaccttcgtc cagcaccagc agtaaatttt tcgggtcagg caataccgct
    38221 tcgctttcca ttgccgccat caccagcgca tggtttgcca ccaccacttc cgcttcctga
    38281 atttcccgac gagcgacaaa aaacgggcat tcgcgatagt agtaacagtt gcggttgagg
    38341 cagctggctt tgtcggtact caaacgacgc cagagatcat catctatagc gatatcagta
    38401 tgatcgcgca ggccatccca tttataagtg tcgagatcgc ccttcagctt cgcacaacgt
    38461 ttttgctctt cctgattgtt cggcgtcagt tcgtcgtcaa gaaacgccag cagatcctgt
    38521 tgcgtgggct cagtgctggc gagcgctgtc agattacgcg ggcaaacgta gcgcccacgc
    38581 ccaaaagcgg cagtgaattt aagatcggga atgatctttt tcagcagcgg taaatctttg
    38641 ctgtagatct gatcctgcaa tgccacgttg gcggtactta ccaccagcgt tttttgctct
    38701 tcgcgggcaa tggcgatgcc ggggatcaaa taggagagcg ttttcccaac gccggtagga
    38761 gcttcaatcg ccagatgccg cccttcttct ccggccagcg ttttggcgac gtccgcaatc
    38821 atctgccgct gcggcgcacg gggaataaag tcggggatct gttcctgaag cgccttatac
    38881 caggcggcaa tttgcgcttt aagcgcggcg gttaatgcca tgagaaaacc tgaaatactg
    38941 tataaacagc caatattgtg gcatttttcg gttttcaggg gtaatggttt ttctgtttct
    39001 ggaaagcggc tcgcaataac cagcaggatg atgcgtaaag cgcttcgcgc taaattcgaa
    39061 caacatgcag aactgcgtac actcttgctg gcaaccgcgt ccgcaaaact ggttgagcat
    39121 acgcaaaatg atgcttactg gggagatggc ggtaatggtc agggcaagaa tcgcctgggg
    39181 taccttttaa tggcgttgcg cggacaattg gctgcggaga agtaacgcat cgggtggctt
    39241 gtgggcgtta aaacagagaa atctttttgc cgcgctcgca aatggctgac aagtgcttgt
    39301 tgtgaaatgc cggatgcggc gcgagcgcct tatccggcct acaaaaacat gcacattcaa
    39361 tatattgcag agttcacgta ggcctgataa gcgtagcgta tcaggcagtt ttgtgtttgt
    39421 catcagtctc atgccgggca tagcccggca taaaagatta ctgcgcagcg gcaggtttac
    39481 gcggacggcg gcgacgttgt tgttcgcctg ccggtttggc atcgccgaga cgacgagacg
    39541 gtttttctgc gggcttcgcg ttaccagact tcgcaccact ttccgcacgg cgtggttgct
    39601 gttgaccgcg accaccgccc tgtccacgac cgccgccacg ttgctggcga ccgttttgga
    39661 tcggttcggc tttgattgac gggtccggct catagcccag aatcgcaatg cgcgggatct
    39721 cttttttcag cagtttttcg atatcacgca gcagtttgtg ttcatcaaca cacaccagcg
    39781 acaatgcttc gccagttgcc gccgcacggc cagtacgccc gatacggtga acataatctt
    39841 ccggtacgtt tggtaactca tagttgacga cgtgcggcaa ctcttcgata tccagaccac
    39901 gcgcagcgat gtcagttgcc accagtacac gaatatcgcc cgatttaaaa tcggccagcg
    39961 cacgagtacg cgcaccttgc gatttattac cgtggatcgc cgcactacgg atgccatctt
    40021 tattaagctg ttcagccaga tggttagcgc catgtttggt acgggtaaac accagcacct
    40081 gctgccagtt ccctttccca atcatatgcg acagcaattc gcgtttgcgt ttcttatcga
    40141 caaagtgaac gtgctgggtc acctgatcag acgcagtatt gcggcgtgcc acttcgattt
    40201 ccagcgggtt gtgcaacagt ttttccgcca gggctttaat atcgtcagag aaggtcgcgg
    40261 agaacaacag gttctggcgc ttcgctggca gttttgttaa cacgcgacgg atatcgtgga
    40321 taaagcccat gtcgagcatg cggtcagctt catcaaggac gaggatttca acctgatcca
    40381 gcttcactgc attttgatgt tccaggtcca gcagacgtcc cggcgttgcc accagcacat
    40441 caacgccgcc gcgcagcttc atcatctgcg ggttaatgct gacaccgcca aacaccacca
    40501 gcgaacgaat gttcaggtat ttgctgtaat cacggacgtt ttcgccaatc tgcgccgcca
    40561 gttcacgggt cggggtaaga atgagcgcac gcaccggacg acgccctttg gcgtgcggct
    40621 ggcgagtgat caggtgttgc aacagcggca gcgtaaagcc cgctgtttta cctgtaccgg
    40681 tctgggcgct ggccatcagg tcgcggcctt ccagcaccgc agggatcgcc tgctgctgaa
    40741 taggggtggg ttcacggtaa ccctgctcgg caacggcgcg caggatatca gggcttaaac
    40801 ccaaagaatc gaaagacata actactccga accgccccga ccgttaccgg tgtagttttc
    40861 agggagatac tgaaaaggaa aatgacaaaa accacaatgt catgagggag cggagtgtag
    40921 cagtttttgt gacgcagcgc ataaattatc cctgtgactg gcgtagctaa aattcttagc
    40981 catactggac aactccccta tggagtcata atcttaatca atcatttgat taagaatgga
    41041 ctgtgcgatg aataatcctg ccatgacaat caagggtgaa caggcgaaaa aacagctgat
    41101 tgctgcggca ctggcacagt ttggtgaata tggaatgaac gccaccaccc gcgagatagc
    41161 cgcccaggcc gggcagaata tcgctgccat cacctactac ttcggttcga aagaagattt
    41221 gtacctcgcc tgcgcccagt ggattgctga ttttattggc gagcagttcc gtccgcacgc
    41281 cgaagaagcc gaacgtttgt tcgcgcaacc acagccggat cgggctgcca tccgtgaact
    41341 gatccttcgc gcctgcagaa acatgattaa gctgctcacc caggatgaca ccgtcaacct
    41401 cagcaaattt atctcccgtg agcagctctc tcccacggca gcctaccacc tggtgcacga
    41461 acaggtgatt agtccgctac acagtcacct tacacgcctg attgccgcct ggaccggctg
    41521 cgacgctagc gatacccgca tgatccttca tacccatgcg ttgattggtg agattctggc
    41581 gtttcgtctt ggcaaagaaa ctattctgtt acgtaccggc tggaccgcgt tcgatgaaga
    41641 aaagaccgaa ctgatcaacc agacggtgac ctgtcatatt gacctgattt tgcaaggatt
    41701 atcgcaaagg agtttgtagt gatgaaaaaa cctgtcgtga tcggactggc ggtagtagta
    41761 cttgccgccg tggttgccgg aggctactgg tggtatcaaa gccgccagga taacggcctg
    41821 acgctgtatg gcaacgtgga tattcgtacg gtgaatctta gtttccgtgt tggggggcgc
    41881 gttgagtcgc tggcggtgga cgaaggtgat gcgatcaaag cgggccaggt gctgggcgaa
    41941 ctggatcaca agccgtatga gattgccctg atgcaggcga aagcgggtgt ttcggtggct
    42001 caggcgcagt atgacctgat gcttgccggg tatcgagatg aagaaatcgc tcaggccgcc
    42061 gcagcggtga aacaggcgca agctgcctat gactatgcgc agaacttcta taaccgccag
    42121 caaggactgt ggaaaagccg caccatttcg gcaaatgacc tagaaaatgc ccgctcctcg
    42181 cgcgaccagg cgcaggccac gctgaaatca gcgcaggata aattgcgtca gtaccgttcc
    42241 ggtaaccgcg aacaggacat cgcccaggcg aaagccagcc tcgaacaagc acaggcgcaa
    42301 ctggcgcagg cggagctgaa tttgcaggac tcaacgttga tagcaccgtc tgatggcacg
    42361 ctgttaacgc gcgctgtaga gccaggcacg gtgcttaatg aaggtggcac ggtatttacc
    42421 gtctcgctga cgcgtccggt gtgggtacgc gcctatgttg atgaacgtaa tcttgaccag
    42481 gcccagccgg ggcgcaaagt gttgctttat accgatggtc gcccggacaa gccgtatcac
    42541 gggcagattg gtttcgtttc gccgactgct gaatttaccc cgaaaaccgt cgaaacaccg
    42601 gatctgcgta ccgacctcgt ctatcgcctg cgtattgtgg tgaccgacgc cgatgatgcg
    42661 ttacgccagg gaatgccggt aacggtgcaa ttcggtgacg aggcaggaca tgaatgatgc
    42721 cgttatcacg ctgaacggcc tggaaaaacg ctttccgggc atggacaagc ccgccgtcgc
    42781 accgctcgac tgcaccattc acgccggtta tgtgacgggg ctggttgggc cggacggtgc
    42841 gggcaaaacc acgctgatgc ggatgctggc gggattactg aaacccgaca gcggcagtgc
    42901 cacggtgatt ggctttgatc cgatcaaaaa cgacggcgcg ctgcacgccg tgctcggcta
    42961 tatgccgcag aaattcggcc tgtatgaaga tctgacggtg atggagaacc tcaatctgta
    43021 cgcggatttg cgcagcgtca ccggcgaggc acggaagcaa acttttgctc gcctgctgga
    43081 gtttacgtct cttggcccgt ttaccggacg cctggcgggc aagctctccg gtgggatgaa
    43141 acaaaaactt ggcctggcct gtaccctggt gggcgaaccg aaagtgttgc tgctcgatga
    43201 acccggcgtc ggcgttgacc ctatctcacg gcgcgaactg tggcagatgg tgcatgagct
    43261 ggcgggcgaa gggatgttaa tcctctggag tacctcgtat ctcgacgaag ccgagcagtg
    43321 ccgtgacgtg ttactgatga acgaaggcga gctgctgtat cagggagaac cgacggccct
    43381 gactcaaacc atggccggac gcagctttct gatgaccagc ccgcacgagg gcaaccgcaa
    43441 actgttgcaa cgggcattga aactgccgca ggtcagcgac ggcatgattc aggggaaatc
    43501 ggtacgtctg atcctcaaaa aagagaccac accagacgat attcgccatg ccgacgggat
    43561 gccggaaatc aacattaacg aaactacgcc acgttttgaa gatgcgttta ttgatttgct
    43621 gggcggtgcc ggaacctcgg aatcgccgct gggcgcaata ttgcatacgg tggaaggtac
    43681 acctggcgag acggtgatcg aagcgaaaga gctgaccaaa aagtttggcg attttgccgc
    43741 caccgatcac gtcaactttg ccgtcaaacg cggtgaaatc tttggtttgc tcgggccaaa
    43801 cggcgcaggg aaatcgacca cctttaagat gatgtgcggt ttgctggtac cgacctctgg
    43861 tcaggcgctg gtgctgggca tggatctgaa agagagttcc ggtaaagcgc gccagcatct
    43921 cggctatatg gcgcaaaaat tttcgctcta cggcaacctg acggtcgaac agaatttacg
    43981 ctttttctct ggtgtgtatg gcttacgcgg tcgggcgcag aacgaaaaaa tctcccgtat
    44041 gagcgaggcg ttcggcctga aaagtatcgc ctcccacgcg accgatgaac tgccattagg
    44101 ttttaaacag cggctggcgc tggcctgttc gctgatgcat gaaccggaca ttctgtttct
    44161 cgacgaaccg acgtccggcg ttgatcccct cacccgccgt gaattttggc tacatatcaa
    44221 cagtatggta gagaaaggcg tcacggtgat ggtcaccacc cactttatgg atgaagcgga
    44281 atattgcgac cgcatcggcc tggtgtaccg cgggaaatta atcgccagcg gcacaccgga
    44341 cgatttgaaa gcgcagtcgg ccaacgatga gcaacccgat cccacgatgg agcaagcctt
    44401 tattcagttg atccacgact gggataagga gcatagcaat gagtaatccg atcctgtcct
    44461 ggcgtcgcgt gcgggcgctg tgcgtcaaag agacgcggca gatcgttcgc gatccgagta
    44521 gctggctgat tgcagtagtg atcccactgc tactgctgtt tatttttgga tacggcatta
    44581 acctcgactc cagcaagctg cgcgtcggga ttttactgga acaacgtagc gaagcggcgc
    44641 tggatttcac ccacaccatg accggttcgc cctacatcga cgccaccatc agcgataacc
    44701 gtcaggaact gatcgccaaa atgcaggcgg ggaaaattcg cggtctggtg gttattccgg
    44761 tggatttcgc cgaacagatg gagcgcgcca acgccatcgc accgattcag gtgattaccg
    44821 acggcagtga gccgaatacc gctaactttg tgcaggggta tgtcgaaggg atctggcaga
    44881 tctggcaaat gcagcgagcg gaggataacg ggcagacttt tgaaccgctt attgatgtac
    44941 aaacccgcta ctggtttaac ccggcggcga taagccagca ctttattatc cccggtgcgg
    45001 tgactattat catgacggtc atcggtgcga ttctcacctc gctggtggtg gcgcgagaat
    45061 gggaacgcgg caccatggag gctttgctct ctacggagat tacccgcacg gagctgctgc
    45121 tgtgtaagct gatcccttat tactttctcg ggatgctggc gatgttgctg tgtatgctgg
    45181 tgtcggtgtt tattctcggc gtgccgtatc gcgggtcgct gctgattctg ttttttatct
    45241 ccagcctgtt tttactcagt accctgggga tggggctgct gatttccacg attacccgca
    45301 accagttcaa cgccgctcag gtggccctga acgcggcttt tctgccgtcg attatgcttt
    45361 ccggctttat atttcagata gacagtatgc ccgcggtgat ccgcgcggtg acgtacatta
    45421 ttcccgcacg ttatttcgtc agcactctgc aaagcctgtt cctcgccggg aatattccag
    45481 tggtgctgat agtgaacgtg ctgtttttga tcgcttcggc ggtgatgttt atcggcctga
    45541 cgtggctgaa aaccaaacgt cggctggatt agggagaaga gcatgtttca tcgcttatgg
    45601 acgttaatcc gcaaagagtt gcagtcgctg ctgcgcgaac cgcaaacccg cgcaattctg
    45661 attttacccg tgctgattca ggtgatcctg ttcccgttcg ccgccacgct ggaagtgacc
    45721 aacgccacca tcgccatcta cgatgaagat aacggcgagc actcagtaga acttactcaa
    45781 cgttttgccc gcgccagcgc ctttacccat gtgctgctgc tgaaaagccc gcaggagatc
    45841 cgcccgacca tcgacacaca aaaggcgtta ctactggtgc gtttcccggc tgacttctcg
    45901 cgcaaactgg ataccttcca gaccgcgccg ttgcagttga tcctcgacgg gcgtaactcc
    45961 aacagtgcgc aaattgccgc caactacctg caacagatcg tcaaaaatta tcagcaggag
    46021 ctgctggaag gaaaaccgaa acccaacaac agcgagctgg tggtacgcaa ctggtataac
    46081 ccgaatctcg actacaaatg gtttgtggtg ccgtcgctga tcgccatgat caccactatc
    46141 ggcgtaatga tcgtcacttc actttccgtc gcccgcgaac gtgaacaagg tacgctcgat
    46201 cagttgctgg tttcgcccct caccacctgg cagatattca tcggcaaagc cgtaccggca
    46261 ttaattgtcg ccaccttcca ggccaccatt gtgctggcga ttggtatctg ggcgtatcaa
    46321 atccccttcg ccggatcgct ggcgctgttc tactttacga tggtgattta cggtttatcg
    46381 ctggtgggat tcggtctgtt gatttcatca ctctgttcaa cacaacagca ggcgtttatc
    46441 ggcgtgtttg tctttatgat gcccgccatt ctcctttccg gttacgtttc gccggtggaa
    46501 aacatgccag tgtggctgca aaatctgacg tggattaacc ctattcgcca ctttacggac
    46561 attaccaagc agatttattt gaaggatgca agtctggata ttgtgtggaa tagtttgtgg
    46621 ccgctactgg tgataacggc cacgacaggg tcagcggcgt acgcgatgtt tagacgtaag
    46681 gtgatgtaac ttcttatctt tcgccagcaa agacaccacc gccgggccgg caaggattgc
    46741 cagccctgca attgccagca aaaagttgtt ttccagtacg cgggacaaca gccacagcac
    46801 aatcagcgct gcaccaaaat accaggtcgt ggtcagctct tccagcacgt ctgccacctc
    46861 acgccagcgt tgctctgggt ggcgctgaaa caccagcatc atcactaccg tgacacaata
    46921 cagtgcgcat aatcctacgc cgacgtgaac cagagtttta ctcatccaac ccaccaccag
    46981 cagcgccact accagtaaat gcaacataat ctgccagcaa cttaggccag ttgcgacacg
    47041 aacacgttgt tgccacttca tggcttctct cctgaagaat ttatctctac ttattcagag
    47101 taccgaactt tacggaaaat tccgtaagac cgcacctttt tgtgacgccg actacactat
    47161 ttcaatgaga taagaggcaa agacaggaaa attatgcccg atcaaacaca acaattttcg
    47221 ttcaaggtgc tcaccatcaa tattcacaaa ggctttaccg cgtttaaccg acgcttcatt
    47281 ttaccggaac ttcgcgacgc cgtgcgtacc gtcagcgccg atattgtttg cctgcaggaa
    47341 gtgatgggcg cgcacgaagt tcatccgctg catgtggaaa actggcccga tacctcgcac
    47401 tacgagtttc tcgccgacac catgtggagc gatttcgcct acggtcgcaa tgccgtatac
    47461 ccggaaggac atcacggtaa cgccgttctt tcacgttatc ccattgaaca ttatgagaat
    47521 cgtgatgttt cggtcgatgg tgcggaaaag cgcggcgtgc tctactgccg cattgtgccg
    47581 ccgatgaccg ggaaagcgat tcatgtgatg tgcgtacatc tgggcctacg tgaggcgcac
    47641 cgtcaggcgc agcttgcgat gctcgccgaa tgggtgaatg agctaccgga cggcgaatcg
    47701 gtattggtag cgggtgattt caacgactgg cggcaaaaag ctaatcatcc gttaaaagtg
    47761 ctggccgggc tggatgagat ttttacccgc gcccacggac gtccggcgcg cacgtttccg
    47821 gtgcaatttc ctctactacg actggacagg atctacgtca aaaatgccag cgccagcgcg
    47881 ccaaccgcgt tgccgctgcg gacatggcga cacctttctg atcatgcccc tttaagtgcg
    47941 gagattcatt tatgaaatgt agctggcgcg aaggcaatat gatccagttg ctggaaaacg
    48001 gcgagcaata ttatcccgcg gtgtttaagg cgattggcga ggcgcaagaa cgcatcattc
    48061 ttgaaacgtt tatctggttt gaggatgacg tcggcaaaca gctgcatgcg gcgctattgg
    48121 cagcagcgca acgcggggta aaagcggaag tcttgctgga tggctacggt tcgccggatc
    48181 tcagcgatga atttgtcaat gaactgacgg cagctggcgt ggtgttccgc tactacgatc
    48241 cccgccctcg cctttttggt atgcgcacca atgtgtttcg ccggatgcat cgcaaaattg
    48301 tggtgatcga cgcgcgtatc gcctttattg gcgggctgaa ttactccgcc gagcatatgt
    48361 ccagctacgg cccggaggcc aaacaggatt acgcggtacg cctcgaaggg ccgattgtcg
    48421 aagatattct ccagtttgag ctggaaaacc tgccaggaca aagcacggcg cgacgctggt
    48481 ggcgacgcca tcataaagcg gaagagaacc gccagccggg agaagcgcag gtattgctgg
    48541 tctggcgcga taacgaagaa catcgcgatg atatcgaacg tcactatctg aaaatgctca
    48601 ctcaggcgcg gcgggaagtg attatcgcca acgcctactt cttccccggc tatcgttttt
    48661 tacacgcctt gcgtaaagcg gcacgacgcg gggtgcggat caaactgatc attcagggcg
    48721 aaccggatat gccgattgtc agagtcggcg cgcgtttgct gtataactat ctggttaaag
    48781 gtggcgttca ggtgtttgag taccgccgcc gcccgctcca cggcaaagtg gcattgatgg
    48841 acgatcactg ggcgacagta gggtccagta atctcgatcc gctcagtttg tcactgaatc
    48901 tcgaagcaaa tgtcatcatc cacgatcgta attttaacca gacgctgcgc gataatctga
    48961 acggcattat cgccgcagat tgtcagcagg tcgatgagac catgctgccg aaacgcacct
    49021 ggtggaacct gactaaaagc gtgctggcgt tccactttct acgccacttc ccggcgctgg
    49081 tgggctggct tccggcgcac acgccacgtc tggcgcaggt tgatcccccc gcacaaccga
    49141 caatggaaac gcaggatcgg gtagaaactg aaaacacggg ggtaaaaccc tgatgagtaa
    49201 atcacacccg cgctggcgct tagcaaagaa gatcctcacc tggctgtttt ttatcgcggt
    49261 gattgtgttg ttggtggtct acgccaaaaa agtggactgg gaagaggtct ggaaggtcat
    49321 ccgagactac aatcgcgttg cactgctcag tgcggtcggg ctggtggtcg tcagctatct
    49381 gatttacggt tgctacgacc tgctcgcccg tttctactgc ggtcacaaac tggcgaagcg
    49441 ccaggtgatg ctggtgtcgt ttatctgcta cgccttcaac ctgacactca gtacctgggt
    49501 cggcggcatt ggtatgcgct atcgtttgta ctcccgactg gggttaccgg gcagcactat
    49561 tacgcggatt ttttcgctca gtattaccac caactggcta ggctatattt tgctagcggg
    49621 ggttatcttt accgcaggcg tggtggagtt gccggatcac tggtatgtcg atcaaactac
    49681 gctgcgtatt ctcggcattg gcttactgat gattatcgcg gtttatttgt ggttttgcgc
    49741 tttcgcgaag caccgccata tgaccatcaa agggcaaaag ctggtgctgc cttcgtggaa
    49801 attcgccctc gcccagatgc tgatttccag cgttaactgg atggtaatgg gagcgattat
    49861 ctggctgtta cttggtcaaa gcgtaagcta tttctttgta ctgggcgtgt tgctggttag
    49921 tagtattgct ggcgtcatcg tgcatattcc ggcgggaatt ggtgtgctgg aagcggtgtt
    49981 tatcgcgcta ctggctgggg agcatacctc caaaggcaca attatcgccg ccctacttgc
    50041 ttaccgtgtg ctgtattact ttatcccact gctgctggcg ctgatctgtt acctgttgct
    50101 ggaaagccag gcgaagaagc tacgggcgaa aaatgaagcg gcgatgtgaa gtatagttaa
    50161 gttctttagt atgtgcattt acggctaatg aaaaaaccgc gtatgccttt gccagacaag
    50221 cgttatagct atagcagcaa gaatcccaaa gaaaccgata aaatagtaat agagtgttaa
    50281 tgcacctata aaagcacaac gaaccggact ccataattct tcactatggc tttttcctgt
    50341 cagttcaagg agcttatttc gtccatgcga gataatgcct gaccataaga caatcattaa
    50401 gcaacttatt acccaaatgg gtcgttcact cattaatgtg gcattcacga tgattaccag
    50461 ggccaaccct gtcaacgtca tcataatgat aaaacgatga gaaccaggat caaatttaaa
    50521 caatagacct gccagcatac tgattaaaaa catcgatccc gcagtgctga acacgacgat
    50581 aatggcagat acaggcgcta aactcgcaac gacaatcgcc accaaagaga ttaaaaacaa
    50641 atatattacg cccgcgatgg cggtatttat cttgttgata tctttactta agccatacat
    50701 agaaagtaat aataatccta tagcaacata catttgcggt gaatcatatt ttgttgccgt
    50761 aatttcgaga tacttagcgc cccaggccag ccctgcggtt gccaccaaac ccaaagcggt
    50821 aatgagccat atgccgttta atatcctggc ttcgtgctga aaatctaatt tattgctatt
    50881 ttgcgagtat gattccattc ttttagttgt ccttagaaaa aacattaata ttcaccatca
    50941 ataaatttaa aaccacgcat acaaaatact tttgcattta tggatacaga aaacgcttcc
    51001 gctcgtccat aaggcatatt ttatacctgg tacttgttaa gtgtcgtttt taataagaaa
    51061 aaaaatcccg acacatggcc gggatattga tgatgaaaaa gaattaacgg cggttgccga
    51121 agatccgcag caacatcagg aacaggttga tgaagtccag atacaaggtt aacgcgccaa
    51181 gaatggaata tttgcgcagg ttcgacgtgt cgcgagtatc aatctgctca cccatatttt
    51241 tcagtttctg ggtgtcatac gccgtcaatc cgacaaagac aatcacgccg atgtaggtga
    51301 ctgcccacat caatgcttcg cttttcagcc agaagttaac cagcgatgcc agcacaatgc
    51361 cgattaacgc cataaacagc atattgccaa agccgcttag atcgcgcttc gtggtgtaac
    51421 cgtacaggct cattgcgccg aacatcccgg cagtaacgac gaaagtactg gcgatagaag
    51481 cagcggtata gacaatgaaa atactggaaa gcgtaagacc cgtcagcgcc gaataaagca
    51541 taaagagcat cgtcgttaca cctgcgctca gcttttgaat catcgctgat aacacaataa
    51601 ccaatgctaa ttgcgcgatg atcagaccga ttaaaaagac acggttagta aacaacagct
    51661 ccatcacggc cgcggaatta gccgcatacc aggcaacaaa tgctgtcagc aacaagccaa
    51721 cggtcatcca gccatagact tgcgccatat aagtttgcaa gccagcccgg ggttgtacga
    51781 ttgaatcaga acgtgggaat ctgtccatga ctttctcctg aagatataag gaatatctta
    51841 aggatactgc aaaatgatga ggctgtgcat cgacgcagcg taaacggatg tactgagcgg
    51901 tgaaattgcc ggacgcagcg gtgccttatc cggctaacaa taaactacca gcgttttgcc
    51961 gcctgctgat cgctctcccg agcttcgacc cagcggtcgc cttccggcgt ggcttcgcgc
    52021 ttccagaacg gtgcgcgggt tttgagataa tccataataa actgcccggc ttcaaacgca
    52081 ctgctgcgat gcgcactggt aacaccgaca aaaacaattt catcgcccgg ccataattca
    52141 ccaatgcggt gaattaccgt gacgcgcccc agcggccagc ggttacgcgc ttcatcaacg
    52201 atttctgcca gtgctttttc tgtcattccc ggatagtgtt cgagggttaa tgctttgacg
    52261 ctgtcgccca ggttatggtt gcgcacctta ccggtaaagg tgactaccgc accgtcttcg
    52321 tcacgctcag ccagccacgg gtactcttct cctacgctga acggctgcgg gccgacaaca
    52381 attttggttt ctgccatctt aacctccggt taccggcggg aagaaagcca cttcgtcgcc
    52441 gtcagtcagc gaatggtcaa aactcaccag cgtctggttg acagcagcca gcaatttgcc
    52501 atcttccagc gccagagccc agcgatcgct ctgcgcagcc agatgctggc gtaacgcttc
    52561 aacggttggg aaatccgcag ccacttcggt tgcatcagtt cccaccaact cgcgcacctg
    52621 ggcgaaaaaa agaacgttaa tcatccgctt ccaccttaaa gtcacccgac ttgccgccgc
    52681 tctttgccag caaacgtacc ggaccaatca ccatatcttt ttgcaccgct ttgcacatgt
    52741 cataaatggt cagcgccgcc acggaggccg cggttaacgc ttccatttcg acaccggttt
    52801 tcccggtcag gcggcataag gtttctatac gtacccgatt gtgctccggc tcggcctgta
    52861 aattgacttc aactttgctg agcatcagcg ggtgacacag cgggatcaga tcccaggtgc
    52921 gttttgccgc ctgaataccg gcgatacgcg cagtggcaaa tacgtcgcct ttgtggtggc
    52981 gaccatcaat aatcatcgcc agcgtctcgc tgcgcatggt gacaaaggct tcggcgcgcg
    53041 cttcacgcac ggtttccgct ttggcggaga catcgaccat gtgcgcttcg ccagcggcgt
    53101 tgatatgggt cagttgcgac atacttattt cttcaaatgt ggatggaaat tacacggacg
    53161 cgtacgggca tccagctgcg gcgcaatgat attttcccat gcggtacggc acgctttggt
    53221 cgaacccggc atggcgaaaa tcagcgtttt gttagcgacg cccgctaccg cacgagattg
    53281 caacgtggaa gtgccaatct cttcgaacga caacatccgg aacacttcac caaaaccttc
    53341 aacttcacgg tcgaacaacg gcagcagcgc ttcgggagcc tgatctcctt ccgtcaggcc
    53401 agtaccaccc gtaatcaaca ccacttgtac atcgtcgctg gcgatccacg cagagacctg
    53461 agcgcgaata gcgtagcggt tttctttcac aatggcttta tcgacaacgt gatggcccgc
    53521 ttcttgcgcc gagtcgcgaa gatagtgacc ggaggtatcg tcttcttcac cgcgacgatt
    53581 agaaaccgta agaatagcaa tacgggtcgg gataaattca gtgcttacct gactcatctg
    53641 atctctcctt ttgacgtttt agccaccaat gtacgataag ttttgcgtaa taccggtgtt
    53701 attttgatgc aggaaatggg tctgtttttt ctcccgcagc gccgctgaaa tacgcgcttc
    53761 cagcgcctgt tgctgggtat cgttttccag cagatcgcgc aggttaacgc cgccttcacc
    53821 aaacaggcag agatggagtt taccaatgga ggaaacgcgc aggcggttgc aagtggcgca
    53881 gaaatctttt tcatacggca tgataaggcc aatctctccg gcgtaatccg gatgacaaaa
    53941 gacttgcgcg ggaccgtcgc tgcgttgacg taattggtgg atccagccgc gacgcagtaa
    54001 ctcgtcacgc agaacctgac cagagatgtg atgcttacgg aagagctcgc tgccctcgcc
    54061 cgtttccatc agttcgatga aacgcagctg gatgggacga tgctggatcc agttcagaaa
    54121 ggtgtcgagc tggtgatgat tcacatcacg catcagcacg gtattgactt tgaccttctc
    54181 aaaaccggcc tcaaatgcag catcgattcc tgccatgacc tgattgaatt tatcctgccc
    54241 ggtaatggca tgaaactggc gagcgtcaag gctatcaacg ctgacgttga tgccagtaag
    54301 tccagcatcg cgccagttcg ccacatcgcg ctccagacgg taaccattgg tggtgaccgc
    54361 tatctggcga atagcgtcgt tttctcgcac agcggcgatg atatcggtaa agtcgcggcg
    54421 taaagatggc tcaccacctg tcagacggac tttttcggtg cccagactgg cgaaggcgcg
    54481 cgtaacccgg cgaatttcat cgacggtcag gaagccttta ttggtgacgc cgctcggctt
    54541 gtaaccatcc ggcaggcagt aggtgcaacg aaagttacac acatcagtaa tcgacaggcg
    54601 caagtagtaa aacttacgcg caaatgcatc agtcagttgt gaagccatgt acacctttcc
    54661 agatacggga ggcgaagtca tttcttcctt cgccctggtg gcaatcttta cgagcattgt
    54721 cacggccaaa gcaccgtatc agttgaccca ggtgcagagg ctagagtgtt tagtggttaa
    54781 gccgatacta gcgtgtaaat gagattttta ccatccacac tttcgctatg taatcatgta
    54841 tatagcgtca tgatcgtgct atttcgctac agaataaggg aaaatggcgg ttttactttg
    54901 atatacatca tcagggaggc atagcgtgca tcgtccttta gaggtagaag aaaatagttt
    54961 gtatcctcaa tattggcagg ttaattgctg tttcctcgca atttgcgcta ctgtagcgcg
    55021 gataatctga ctccaggaaa ctatatgcgc aatcgtacgc tggctgatct tgatcgtgtc
    55081 gttgctctcg gcggagggca tggactggga cgcgttctct catcactttc gtctttgggt
    55141 tctcgtttaa cgggtatcgt caccaccacc gataacggtg gctcgacggg gcgtattcgc
    55201 cgctcagaag gcggcattgc ctggggcgat atgcgcaact gcctcaatca gctgataact
    55261 gaacccagcg tcgcttccgc aatgtttgaa tatcgtttcg gcggtaatgg cgaactttcc
    55321 gggcacaacc ttggaaacct gatgttaaag gcactggatc accttagcgt gcgacctctt
    55381 gaagcgatca atctgattcg aaatctgctg aaagtggacg cacatttgat tccgatgtcg
    55441 gagcatcctg ttgatctgat ggcgattgac gatcaggggc atgaagttta cggcgaggtc
    55501 aatatcgacc agttaactgc gccgattcaa gagttattgt taacgccgaa tgtacccgca
    55561 acgcgtgagg cggttcacgc tatcagtgaa gcggatctca tcattattgg gcctggcagt
    55621 ttttacacca gcctgatgcc aattctgctg ctgaaggaaa tcgcacaggc attacgccgc
    55681 acgccagcgc cgatggtcta tatcggcaat ctggggcgtg agttgagttt acctgcggct
    55741 aatctgaagc tggaaagcaa gctggcaatt atggagcagt atgttggtaa aaaggtaatt
    55801 gatgcggtca tcgtcgggcc aaaagtggat gtctcggcgg tgaaagagcg gattgtgatt
    55861 caggaagtgc tggaggccag cgatattccg tatcgtcatg accgccagtt gttgcatagc
    55921 gcgctggaaa aggcattaca ggctttaggt taacacgaag ccggaagaat attccggctt
    55981 cgtcatcttg tcacgacgcg gcaataaaca gctcacgcaa ctgatgcaac tggtcacgaa
    56041 tttgcgccgc ttcttcgaac tccagattct gcgcgtgttg catcatcaac ccttccagtt
    56101 catggatctt ctgctgtaac gctttaggcg acatatccat cggcacatta tccggctcaa
    56161 caatcgggcg cgattttcct ctgcccttcg ctttggtttt ggcaatgttc tgccccagcg
    56221 ccaggatatc gaccactttc ttgttcaagc cttgcggcgt aatgccgtgt tcctcgttgt
    56281 acttctgctg tttctcgcgg cgacgttcgg tttcgccaat cgctttcgcc attgatgggg
    56341 tgatcttatc gccgtagaga atcgctttac cgttaacgtt acgtgccgca cgaccaatgg
    56401 tctggatcaa cgaacgttcg gaacgcagga agccttcttt gtcagcgtcg aggatcgcca
    56461 ccagcgaaac ctccggcata tccagacctt cgcgcagtaa gttgatccct accaatacgt
    56521 cgaactcacc cagacgcaag tcgcggataa tctccatacg ttcgacggta tcgatatctg
    56581 agtgaagata acgcacgcgc tcaccgtgtt cttcgagata ttcagtgaga tcttccgcca
    56641 tccgcttggt cagagttgta accagtacgc gttcgttaat tgccgctcgc tgacgaatct
    56701 ccgatagaag atcatccacc tgtgtcgcta ccggacgcac ttcaataatc gggtcgagta
    56761 agcctgttgg acgcacaacc tgatccacca catcgccacc ggatttttcc agctcgtaat
    56821 tacccggcgt cgccgaaaca tagatggttt gcggcgctaa tgcttcgaac tcttcaaatt
    56881 tcagcgggcg gttatccagc gctgatggca agcggaagcc gtactccacc agtgtctctt
    56941 tacgcgcccg gtcaccgcga tacatgccgc caatttgtgg aatggtgacg tgagattcat
    57001 cgaccaccag cagcccatca gcaggcaggt aatcaaacag cgtcggcggt ggctcacccg
    57061 gtccacgacc ggagaggaag cgcgagtagt tctcaatccc cgaacagtag cctagctcgt
    57121 tcatcatctc cagatcaaac tgggtacgct gggtcagccg ctgctcttcc agcagtttgt
    57181 tgttttccaa tagcacttta cgtctggcgg ccagctcttc tttgatctcc tccatcgcct
    57241 ggacgatgcg ctcgcgtggc gtgacgtagt gcgttttcgg gtagatggta aaacgtggaa
    57301 tagtggaaac aatctgcccg gtcagcgggt caaataacga caatcgttcc acctcctcgt
    57361 caaacagctc cacgcgaagt gcaatgtcat ccgattctgc cgggaagata tcaatcacct
    57421 cgccacgaac acggaaagta ccacgctgga atgcttgatc attacgggca tattgcagct
    57481 ccgccagtcg gcgcaggatc gcgcgctgat cgataatcat accgaccgtg agatggagca
    57541 tcatcttgag atataaatca ggatcgccca gaccataaat cgcggaaaca gacgccacca
    57601 caaccacatc acgtcgctcc agcatcgctt tggtggcgga taaacgcatc tgttcgatat
    57661 gttcgtttac cgaggcatct ttctcaataa aggtgtcgga actcggtaca taggcctccg
    57721 gctgatagta gtcgtagtag gagacgaaat attccaccgc gttttctggg aagaattctt
    57781 tcatttcgcc atacagctgg gccgccagcg ttttgttggg cgcaagtacc atggttgggc
    57841 gctgaaggtc agcaatgaca ttggcaatgg tgaaggtttt cccggagcca gtcacgccaa
    57901 gtaacgtctg gtgcgccagg ccatcttcca gcccctcttc gagacgtcga atcgcctccg
    57961 gctgatcgcc agaaggttta aaagcggaat tcagtttgaa cggtttactc atgagtcgct
    58021 acctgaagga gttgggcggg caggtatgta attttactcg tcgtacttaa ttatgccaac
    58081 aaattatact ggataaaaaa acagttcatc accataatat ttctgttaca gcgtaaactc
    58141 cgctgtcaat catgaacaag atttactctg cggcgagata aaactccggc cttaccgggt
    58201 tatccccaaa gcaacggctt ttttaacatt tgtcaagatg attgatgaca gttttatggc
    58261 aagagatgcc tgttcagtga ctgccattgc aattatctaa cctgttaaaa aataaaagat
    58321 atttctttga gctgtcttta acgccaattc gcgtgcaagc cgcgtattct ctcgcttgcc
    58381 tcgtgttttc taactctaat acacatggtt atccacagga atagtggata actgtctgca
    58441 gcccctatcc cccgccgcct gggcaattcc cacattcacc gcatgatgcg gaggtaaaat
    58501 ttttttcgtg atttttttag aatttaattg gttaaattgc agtcaatcgg agacacgatc
    58561 tcgctcgcaa tttaaccaat tacaggatga ctacattaag gcaagattga tgtactttcc
    58621 ggttgccgca ttttctggat tttctgcaag ccagggaatt tcgcccagca gcggcgcggg
    58681 aatcatgcgg gtgagcgtgg tcatatattc agcgtgacgt tttcccggag gcgtgacatc
    58741 gttcgccacc caccccgcca gagtcagtcc ggcgtgtagt attgcctgcg cagtcaacat
    58801 cgcgtgatta atacagccga gtttcacgcc cacaaccagt atcactggca gttgttcctg
    58861 tgttacccaa tccgcaaaag tgaaagtgtc agaaagcggc gtaaaccagc cgccagcacc
    58921 ttccactaac acccagtcag cctgttgttc aagcgcgcgt aatccggcgc tcattaccaa
    58981 tgcttctatc ggcctgccct cttgcgcgct gatgatatgc ggcgaggtgg gttctgcgaa
    59041 ggtgtaagga tttaccgttg cgtaatccag ctgcaggcta ctgttgcgct gtaacgccag
    59101 cgcgtcacta ttacgtaagc ctttcggggt cttttcgctg ccagaggcca ccggtttgta
    59161 acctgccgtc cggtagcctg ctgcctttgc ggcttgtaaa agcgcgcagc tggcgacagt
    59221 tttccccact tcggtatccg ttccggtgac aaaataacat ttactcacga gcaatcactc
    59281 ccaaaaaaag atgatacgtc agaggatatc gcccctgttg ttgcggccag gccagttgca
    59341 atcgctgcaa ctgcgaacgc gttaatattc gcgggtcacg cccttcatga agatgcgtgg
    59401 caccgatgcc tttcagcgaa cgcatggcac tgagcgcatc atcaaaccac agcgtgatgg
    59461 gctgaatata atgttgataa tgcacggcgt ttagcgactg ttcgatttca tctggcggta
    59521 aaaagcgatt agcatgcgga cgctcgtcca ccgcctgcca cgcctgatgc agttcgggta
    59581 acgatccctg caccagcgtg gtaaacgcga ccacgcctcc ggggcgcacc acccgataca
    59641 gctcgcggag tgccgtggat aaattaccgc accactgcac cgcgagattg ctccatgcaa
    59701 gatcgaacgt cgcagtcgct aacggcaggg attcgatatc tcccgccaga taatggtctg
    59761 cggcatcctt ctggcgtgcc tgaacaagca ttggcggaga gagatctaac gcagtcacct
    59821 gcgcgtgacg ctctcgccag cggcggctca tccagcctgg tccacaaccc gcatccagta
    59881 cgcgggtgta tttacgctgt gggagcattg ccagtaaggc gtcagcactc tggcgctgta
    59941 gatcggcgtg ttgctcatag tgtgcggctg cccgtccaaa tgccgcagca atggcttgtt
    60001 tattaaccgt tgccatgcag cacctccagc agacggtcga tatcctgcat ttcatgcgct
    60061 gcggttagcg ttaagcgcag tcgcgcagta ccagcgggta cggttggcgg gcgaattgcc
    60121 gtgacccaac agccttgctg gcgcagtttt tctgccagtt gtaacgcacg gctgttatca
    60181 ccgacgatca atggctggat ggcgctccat gaatcagcaa gcgtaaacgg caaatcctgc
    60241 actccggcac gaaaacgcgt tatgagtgcc gccagttttt cgcgccgtgc atccccctca
    60301 tcactgcgaa tgactgccag cgacgcacgt aatgcctgcg cctgagcggg cggcatactg
    60361 gtgctgtaga taagatggcg agcgaattgc agcagataat ccgccaccgt attggagcaa
    60421 agcaccgctg ccccgctgac gccaaatcct ttgccaaacg tcaccaccag caattctggt
    60481 tttacctttt gcagccagca gctgccacgc ccctgctccc cgataacgcc cgtgccgtgg
    60541 gcgtcatcga ccatcaacca gccatcgtgc tgttgcgtta cctgctggat ttcctccagt
    60601 ggcgcactat cgccgtccat gctgaacacg ccttctgtca ctaccagttg ctgccccgga
    60661 cagggggaag caagcagtcg cgccagatga gtgacatcgt tatgagcaaa acggcgaagc
    60721 ggcgacgggc ttaaacttgc agcctccagc aatgaggcat ggctaagccg gtcggcaaca
    60781 atacggtcct ctttcgccat catcgcggca atgactgcct gattagcagc aaaaccagag
    60841 ataaacagca gtgcccgcga atagcccagc cactcggcca gttcttcttc cagcgcctga
    60901 tgcgccacgc tataaccgct gacgtgaccg gagccgccgc taccgatgcc aaattgctcc
    60961 gcaccctgct tccaggcacg gataatttgc ggatgatggc ttaaacctaa ataatcgtta
    61021 ctggaaaagt tcagatactg gcgatcatcc accaccagcc agcgtccggc tccttgcgcc
    61081 accggataac ggcgacgcag ggcatcggca gcacgccgcg catcgagcgc cgcgttgatt
    61141 ttctcctgcc agctcatagt gctgccgcgt tgtaatattc gtcagtgtcc ggggtcatca
    61201 gcgcctgctc cagacgctgc tgttgttcgt tatcgcccgc cagcacggca gtttgctgcg
    61261 gatttagccc cagtttgcgg aacagttgca ggtctttatc ttcttccgga ttcggcgtgg
    61321 tcagcagttt gcaaccgtag aaaatcgagt ttgcgccagc cataaagcac atcgcctgag
    61381 tctgttcgtt catctgctcg cgtccggcag aaaggcgtac gtaagaggtc ggcatcatga
    61441 tccgcgcaac tgcaatggtg cgaataaaat caaaggcatc gacatcatcg ttatccgcca
    61501 gcggcgtgcc tttcaccttc accagcatgt tgattggtac gctttccggc ggcgttggca
    61561 ggtttgccag ttgcagcaat aatccggcgc gatcttttac tgtttcgcct aagcccacaa
    61621 tgccgcctga acagactttg atcccggcgt cgcgcacttt ttccagcgta tcgaggcgtt
    61681 cctgataggt acgcgtggtg atgatattgc cgtaaaactc cggcgaggtg tcgaggttgt
    61741 ggttgtagta atccagcccg gcattcgcca ggcgctgcgc ctgagattca ctcaacgtgc
    61801 ccagcgtcat acacgcctcc agccccatcg cttttacccc ctgcaccatt tgttccaggt
    61861 acggcatatc gcgttcgtgg ggattcttcc acgccgcgcc catacagaaa cgcgtcgatc
    61921 ccgccgcttt cgctttgcgc gccgactcca gcacctgttc aacttccatc aaccgctcgg
    61981 cttccagccc ggttttgtag cgcgagcttt gcgggcaata tttgcaatct tccggacaag
    62041 ctccggtctt aatcgacagc aaagtgctga cctgcacctg acgaggatcg aaatgctgac
    62101 gatgcacctg ctgcgcttca aacagcagat ccagcaacgg tttttcaaat aattctgtga
    62161 cttgcgacaa tgtccagcgt gggcggtgag ccatggggct tctccaaaac gtgttttttg
    62221 ttgttaattc ggtgtagact cgtaaaccta aatcttttca atttggttta caagtcgatt
    62281 atgacaacgg acgatcttgc ctttgaccaa cgccatatct ggcacccata cacatccatg
    62341 acctccccgc tgccggttta tccggtggca agcgccgaag gttgcgagct aattttgtct
    62401 gacggcagac gcctggttga cggtatgtcg tcctggtggg cggcgatcca cggttacaat
    62461 cacccgcagc ttaatgcggc gatgaagtcg caaattgatg ctatgtcgca tgtgatgttt
    62521 ggcggtatca cccatgcgcc cgccattgag ctgtgccgca aattggtggc aatgacgccg
    62581 caaccactgg agtgcgtttt tctcgcggac tccggctccg tagcggtaga agtggcgatg
    62641 aaaatggcgt tgcagtactg gcaggccaaa ggcgaagcgc gccagcgttt tctaaccttc
    62701 cgcaatggtt atcatggcga tacctttggc gcgatgtcgg tgtgcgatcc ggacaactca
    62761 atgcacaacc tgtggaaagg ctatctgcca gaaaacctgt ttgctcccgc cccgcaaagc
    62821 cgcatggatg gcgaatggga tgagcgcgat atggtgggct ttgcccgcct gatggcggcg
    62881 catcgtcatg aaatcgcggc ggtgatcatt gaaccgattg tccagggcgc aggcgggatg
    62941 cgcatgtacc atccggaatg gttaaaacga atccgcaaaa tgtgcgatcg cgaaggtatc
    63001 ttgctgattg ccgacgagat cgccaccgga tttggtcgta ccggcaaact gtttgcctgt
    63061 gaacatgcag aaatcgcgcc ggatattttg tgtctcggta aagccttaac cggcggcaca
    63121 atgacccttt ccgccacgct caccacgcgc gaggttgcgg aaaccatcag taacggcgaa
    63181 gccggctgct ttatgcatgg gccaactttt atgggcaatc cgctggcctg cgcagcagca
    63241 aacgccagcc tggcgattct cgaatctggc gactggcagc atcaggtggc ggctattgaa
    63301 gcgcagctac gcgagcaact tgcccccgcc tgtgacgccg aaatggttgc cgatgtgcgc
    63361 gtactggggg caatcggcgt ggtcgaaacc tctcgtccgg tgaatatggc agcgctgcaa
    63421 aaattctttg tcgaacaggg tgtctggatc cggccttttg gcaaactgat ttacctgatg
    63481 ccgccctata ttattctctc gcaacagttg cagcgtctga ccgcagcggt taatcgtgcg
    63541 gtgcaggatg aaacattttt ttgccaataa cgggaagtca gcgtgagggt ttctggctac
    63601 actttctgca aacaagaaag gagggctcat gaaactcatc agtaatgatt tacgcgatgg
    63661 cgataagctg ccgcatcgtc atgtctttaa cggcatgggt tacgatggcg ataatatttc
    63721 accgcatctg gcgtgggatg atgttcctgt gggaacgaaa agttttgttg tcacctgcta
    63781 cgacccggat gcgccaactg gctccggctg gtggcactgg gtagttgtta atttacccgc
    63841 ggatacccgc gtattaccgc aagggtttgg atctggtctg gtagcaatgc cagacggcgt
    63901 tttgcagacg cgtaccgact ttggtaaaac cggatacgat ggcgcagcgc cgccgaaagg
    63961 cgaaacccat cgctacattt ttaccgttca cgcgctggat gtagaacgta ttgatgtcga
    64021 tgaaggtgcc agcggcgcga tggtcgggtt taacgttcat tttcactctc tggcgagtgc
    64081 ctcgattact gcgatgttta gttaatcact ctgccagatg gcgcaatgcc atctggtatc
    64141 acttaaaggt attaaaaaca actttttgtc tttttacctt cccgtttcgc tcaagttagt
    64201 ataaaaaagc aggcttcaac ggattcattt ttctatttca tagcccggag caacctgtga
    64261 acacattttc agtttcccgt ctggcgctgg cattggcttt tggcgtgacg ctgaccgcct
    64321 gtagctcaac accgcccgat caacgtcctt ctgatcaaac cgcgcctggt acctcttctc
    64381 gcccgattct gtcggcaaaa gaagcgcaga atttcgatgc tcaacactat tttgcatccc
    64441 tgacaccagg tgcggcagcg tggaatcctt ccccgattac cctgcctgcg caacctgact
    64501 ttgttgtcgg cccggcgggt actcaaggtg taacgcatac cacgattcag gcggcggtag
    64561 atgcggcaat tatcaagcgt accaacaagc gccagtatat tgccgtgatg cctggtgagt
    64621 atcagggaac ggtgtatgtc cctgccgctc cgggtggaat tactctgtac ggtacaggtg
    64681 aaaaaccgat tgatgtgaag attgggcttt cccttgatgg tggcatgagc cctgccgact
    64741 ggcgtcacga cgtcaacccg cgcggcaaat atatgccagg taaaccggcg tggtatatgt
    64801 acgatagctg ccagagtaaa cgcagcgaca gtatcggtgt tctctgctct gcggtcttct
    64861 ggtcacaaaa caatggcctg caactgcaaa acctgaccat cgaaaacacg ctgggcgata
    64921 gcgtagatgc gggtaaccat ccggcggtgg cactgcgtac tgatggcgac aaagtgcaga
    64981 tcaataacgt caacattctc ggtcgtcaga acaccttctt tgtcaccaac agcggtgtgc
    65041 agaaccgtct ggaaacgaat cgccagccgc gtacgctggt gaccaacagc tatattgaag
    65101 gggatgtgga tatcgtttct ggtcgcggcg cagtggtgtt cgataacacc gaattccgcg
    65161 tggtgaactc ccgtacccag caagaagcgt atgtgtttgc accggctacg ctgtccaaca
    65221 tttactacgg tttcctcgcc gtaaacagcc gtttcaatgc ttccggtgat ggcgtggcgc
    65281 aactgggccg ctcgctggat gttgatgcca ataccaacgg tcaggtagtg atccgtgata
    65341 gcgccatcaa cgaaggtttt aacacagcca aaccgtgggc tgatgcggtg atctctaatc
    65401 gcccgtttgc gggtaacacc ggcagcgttg atgataacga cgaagtacaa cgcaatctga
    65461 atgacactaa ctacaaccgc atgtgggaat acaataaccg cggcgtgggt agcaaagtgg
    65521 ttgcagaggc gaagaagtag gagctgttaa ctatgtgccg gatgcggcgt aaacgcctta
    65581 tccggcctac agttcgatac gatttgtcgg tcggataaga tgcgccagca tcgcatccga
    65641 caataagtgc cggatgcgac ctacattcac atggcgcttt ttacatctga cggtttttat
    65701 tgaagttaat caaactaccc gccttgataa tctcgcgttc ttcggcagtc agactttcca
    65761 tatagagcgt gatttccgtt accggtgcat cttcatggat cacataacct ttaaacgtcg
    65821 ttccaggatt atccagcgcc gctttaatgc cagggatgta aatgtaatcc cccacttcaa
    65881 aggttggcgc ttccgccatc tgcagcggta acatccccca gttgatgacg ttagaacgat
    65941 agcgtttagt cgcgtactcc tcggcaatat tcgccagacc gccaatcaca cgctgacaac
    66001 tcgccgcctg ttcacgcgca gaaccatcgc ctggtttcac cgcatagacc atgctgccaa
    66061 tttcagtttg cagcggatca acatgttcct gaccagcaat ctgcttaatg cgcgcaaaca
    66121 cctctgccat ctcgctgaca ttccccgcca gacgctgatt ttccagctca gcagtcgctt
    66181 tacttctgcc aacataacct ggatcgcggc gtgacagggt aaactccgcc agaccaatcg
    66241 gatttgaacg ataagaagag gtttcaccgg aaggaatcag ttcgtcggtg gtggtcactt
    66301 cgtcgaggat cttcgagcac actttgagga cgatattgtc agtcagcgca cccaattccg
    66361 gccagtcttt aatgttcggt ccgtaaatca gcggttgctg ggtcgcccct ttcacaaagc
    66421 cttgatagac gcgattttta tacggcgtta catcgaaggc gtactccggc acgttgtccc
    66481 agcaatcgag ttcgctggca gaggttaaat agccaccgtt tgccgcagtc gcagcgatag
    66541 aacgagcgtc catcaacgcc accgctgaca tctgcccatt agctggctta gagccttcgc
    66601 ggttcgggaa gttacgcgtg gtgtggcgaa tactcaaacc gttgttgatt ggcgtatcgc
    66661 ccgcgccaaa gcatgggccg cagaacgcgg ttctgatgat tgcgcctgcg ccaatcaaat
    66721 ctgcgaccac accttttttg gcgagatcca taaacaccgg ctgtgatgac gggtaaaccg
    66781 ctaacgagaa ggtgtcattg ccgcaggatt gaccgcgcag cgcattcgcc gccgcgatga
    66841 cgttttcata gttaccgcca gaacagcccg cgataatccc ctgctgcact ttcaggcgac
    66901 cattttccac tttatccagc agcgagagtt tggctttacc gtgcgccacg cgttcggact
    66961 caatttcaat ctcacgcaga atgtcggtca ggttctggtt cagcgtgtcg atttcataca
    67021 cgttgctcgg gtggaatggc agcgcaatca ttggtttgat ggcgcttaaa tcaacgctga
    67081 tgcagccatc gtagtacgcc attggttgag ggttaagttg gcagtaatcc tggccgcgac
    67141 cgtgcagcgc cagccagtta tggacttctt catcggtttg ccagacagaa cttaaacagg
    67201 tcgtttcagt ggtcatcacg tcaacgctgt tacggaaatc ggtagagagc gctgcaacac
    67261 cgggacctac gaactccatc actttgtttt tgacgtaacc gtttttgaac acggcaccga
    67321 tgatagccag cgccacatcc tgcggcccca catacggcgc aggttttccg gtcagatgca
    67381 ccgcaaccac gcccggatag tcgatatccc aggtgtcatt aagcagttgt tttaccagct
    67441 cgccgccgcc ctcaccgact gccattgtcc ctaatgcgcc gtaacgggtg tggctgtctg
    67501 atccgaggat cattttgccg ccgccagcca tcatttcacg catatattga tggatgaccg
    67561 caatatgcgg tggcacaaaa ataccgccat aacgctgggc cgccgataaa ccaaaaacat
    67621 ggtcatcacc gttaatggtg ccgccgacgg cgcagagtga gttatggcag ttggtcagca
    67681 catacggcag cgggaaacgt tccataccgg acgctttagc ggtctgtaca ataccaacaa
    67741 aggtaatatc gtgagaggct aatgaatcaa acttaatttt aagtttatcc atatttccgg
    67801 acgtattatg agaagagaga atagaccagg caatagtgcc ttttttggct tcttcttttt
    67861 taatttcgcc ggtgaaatgt tcttcggcaa ttatttcgtt attactggcg agaaacacgc
    67921 ctttttcaga taacttgatc atcaaatgct ccagatatct gcgcaccgga aagtgcgcag
    67981 aaagataata aatggatata ctctaaataa ttcgagttgc aggaaggcga caagcgagtg
    68041 aatccccagt cacttacata agtaagtgac tggggtgagc gaacgcagac gcagcacatg
    68101 caacttgaag tatgacgagt atatttacag catgttccag ccgatcagca tattccacca
    68161 ccacacgccg agggtgatat gcaccaggaa ggttaatatc gtcagtaccg caccgaccaa
    68221 ccaccaggat ttaatatcgt tgtaacccac gccaaagatg accggacctg ccgcgccgcc
    68281 atagtgagta accatgccgc cataggagtt agagaacaac agtgccagcg cggttaacat
    68341 taacggtgcg ccggagacat tcgccagcat ggcaaatacc ggtaacatgg caacgatata
    68401 ggcactacca gaagcgaaga aataacgcac gatgatgctg aggaaaataa taacgaagaa
    68461 agcaacgttc ccgtgaccat caaatgccag gttattttta aagacttcag ctaaccattc
    68521 gaagaattta actttcgata ataaggagct taagccgata ataccgccgt accagattaa
    68581 ggtattccag ccgcctttat ttttaaccac gtcttcccag gtaacgatac ccagcagcag
    68641 catagttgcc ataacaacga ttgccacggt ggattcatca acccccagag acttactgaa
    68701 aatccagccc agcagcgcca gcacaaagac accgagcagc attttttcgc ggattttcat
    68761 cggtcccagt tcggcaaggc ccgctttagc gatggttttg ttatccacct tcttaatttc
    68821 tggtggatac atggtgtaaa tcaccagcgg ggtgaccagc agcataatga tgcccggcaa
    68881 tccggcggct aacgcccatc caccccagct aatttgcagg tgcagaatgt cgttgatcat
    68941 tttcagcgcc agaatgttcc ccgccattgc ggtaaagaac atatagctgg tggttttggt
    69001 gaccatgtaa atggacatca tcaggtaatg tccaacacga cgcggacttt tttccggttc
    69061 tgatcccaaa gccactgcca cgctgttgat gatcggtaac acgatgccgc ccgcacgcgc
    69121 ggtgttagac ggtgttgccg gagccagtac cagatcgaga aataccgtaa cgtaacccag
    69181 acccagggta gtgctaccaa ttttaccaat cagcagatag gcaatacgtt tacctaagcc
    69241 tgtggttaca aacgcggcgc ttaaagtaaa cgcagaaaac accagccagg tggtaccgga
    69301 agagtaaccg cttaatacag cggtggtttt aaattcccca cctgataagt tacccaccac
    69361 taccatcgat gcggcgacgg caattaacag tacgacaggt tccgggaaag gcttgataac
    69421 cagccccaca atggccgcca ggtaaatacc aaaaagcacc cacgccagtt cgcttaatcc
    69481 tgccggagct ggcataaagc caataataca tgggattgct aatatcagaa ttagcttcca
    69541 taacgatttc ttattcattt aatatcctgt tctttctgta tgactcatac agaattcctt
    69601 tattgattgt cattatcacg acaacaaaat ttttcaggga agataaactt caccggaaaa
    69661 tatttttctg gtcgtccgaa taacagatgc gcgtaacgtc gtggcatcct gaccttcatt
    69721 acttaaatga acgtcgagcg caccactggg gtgttcaata ttgatattgc cgtatcctac
    69781 agaagggacg atttgtcggg tgacggtacc ttccaatgca caactactgg aaatagcaat
    69841 agcaccggtt atcgccaaag cgcgatggca agaatgcggc ataaaataac gcacattaat
    69901 tgccccgcct ttctgcgctg gagaaataag tacaggttta gggataacca tattactgac
    69961 atcgcctaaa cccattgctt tacccgcttg tagacggata gattcaatgc gggctaataa
    70021 tgctttgtcg gcatccagct ctgccggtaa ttcatagcct gtttttccca gatattcagc
    70081 aggaataatg acaactggca tcgccatatc gatacaggtc accgggacat cgtcaaaata
    70141 atcaatctga ttatccgtcg ggaagacttt tccggttttc gttccggcgg cattcaggaa
    70201 agtgagcgca accggtgcgg cagtacccgg tacgccgtca attctggcgc taccctcgta
    70261 ctcgacaaca ccatttggcg tttgcacatc agcttcgatg aacgtacccg tattgacgtt
    70321 gcggatacgt acgcgggtaa ctggcgaagt cgctgcaatc aaaccatttt caatggcgaa
    70381 tgccccaacg ccagacagca tattgccgca gttaggcgtg gtatcgacac gttgctcatg
    70441 gacgataact tgagcaaaca gataatcgac atctgcacgc ggatcgctgg agcggctaat
    70501 aatggcgact ttactggtca gcggattacc gccgccaata ccgtcaattt ccagatcgtt
    70561 accggaaccc ataattgcca tcaatatttt atcgcgctgc gtttgatctt cgggtagatg
    70621 ttccgctaac aggaacgcgc ccctcgaggt tccacctcgc atcatcacgc agggtatttt
    70681 tttcataata atgccctcaa tttaaaaaca taacttattg cgatatggtt acattaaggg
    70741 caaagcatct ctaatgactt tagctcaacg attaataaca ttttttcatt aatttaagtt
    70801 ggctaaatgc agttaaaatt tttaactgcc agtcacccaa aatcgtcgct tccattttcc
    70861 ggagtaataa tgaagcatga attatcaagt atgaaggcat ttgtcatact ggcagagtcc
    70921 agttcattta acaatgctgc taaattactc aatattacgc aacctgcatt aacgcgaaga
    70981 ataaaaaaga tggaggaaga tttacacatt caactatttg agcgtacaac tcgcaaggtt
    71041 acgttaacaa aagcaggaaa aaggttgctc ccggaggtgc gggaattaat aaaaaaattc
    71101 gatgaaacgc tttttagtat tcgcgacatg aatgcttatc atcgaggtat ggtgacgtta
    71161 gcgtgtattc cgaccgcggt attttatttt ttaccattgg caatcggtaa atttaatgag
    71221 ctgtatccca atattaaagt gcggattctg gaacaaggca cgaataattg catggaatcg
    71281 gtgctgtgta acgaatcaga ctttggcata aacatgaaca acgtcacaaa ttcatccatt
    71341 gattttaccc cactggtcaa cgagccgttc gtgctggcct gtcggcgtga ccatccattg
    71401 gccaaaaagc agcttgtaga atggcaggag ttagtgggtt acaaaatgat tggcgtacgc
    71461 tcctccagcg gcaaccgact gttgatagaa caacagctag ccgacaagcc ctggaagctg
    71521 gactggtttt acgaagtgcg tcatctttcg acgtcattag ggctggtgga ggcgggactg
    71581 gggatttcgg cgcttcctgg tctggcaatg ccccatgcgc cctattcttc gattattggt
    71641 atcccactgg tggaacccgt tatacgtcgg acattgggga ttattcgccg caaagatgcc
    71701 gtgctttctc cggcagctga acgctttttt gccttgctga ttaatttgtg gactgacgat
    71761 aaagacaatt tgtggaccaa tatcgtcgaa cgccagagac atgcgttaca ggagataggt
    71821 taatacaccg gcgcaggaga gactgcgccg gttaaatcag cggttagtgc gcgttgacca
    71881 ctacccacat tggcccctgc ccaaccgcat agcggccttt ttcatgcagt agcccctgct
    71941 cgccaacaat ttcgtatacc gagatgtggt gagatttttg cccggcggca atcagatact
    72001 tgccgctgtg atcaacattg aagccgcgcg gctgggtttc cgttggctgg aagccttctt
    72061 tactcaacac gctgccatct tccgaaacgc tgaaaacggt aatcagactg gcggtacggt
    72121 cgcaggcgta taaatgacga ccatccgggg tgatatgaat atcagccgcc caacgggtgt
    72181 cggagaagtt ttccggcatc atatccagcg tctggacaca ttcgatattg ccgtgcggat
    72241 ctttcagttc ccagacatcc actgagctgt ttaactcatt gacgcaatac gcatattgtt
    72301 cgtttggatg gaataccata tgacgcgggc cggccccttc aacggtagtc acttccgcag
    72361 ggtcctgcgc caccagatga ccatcatcgc tgaccgtaaa caggcaaatg cgatcctgct
    72421 ttaatgccgg aacccacaac gtacggttgt ccggtgagat attggcggaa tggcaaccgt
    72481 ccagcccctc gaccacatcg acgacgccca ctggcaggcc atcttccaga cgcgttacgc
    72541 tcacgttacc cgcattgtaa gaaccgacaa agacaaactg cccctggtga tcggtggaaa
    72601 tatgcgtcgg gctacccggc agcgcagact ctgcagcaaa ggtcagcgcg ccatcatccg
    72661 gtgcaatacg atacgccaga acacgaaact ccggacggac accaacgtag aggtaacgtt
    72721 tgtccgggct gaccaccatc ggctgcacct gccccggcac atcgacaacc tgtgtcagcg
    72781 tcagtgcgcc ttcatgattc aggttccaga cgtgaatttg ctggctctca gggctggcga
    72841 tataaactgt ttgcttcatg aatgctcctt tgcatttagc aactgactgt aacagctaaa
    72901 attagtcgct tttggcggtg aatgctgaat taaaacgcag aattttgtcc gatagtggta
    72961 tcggtgtacc attcgcgcag acgaaaattc ttaaccttaa tctggaatac gccatgacca
    73021 cacgcgtgat tgctctcgac ttagacggca ccttattgac cccgaaaaag accctgcttc
    73081 catcatcgat agaagccctg gcccgcgctc gcgaagcagg ctatcgatta atcatcgtca
    73141 caggtcgcca tcacgtcgct attcatcctt tttatcaggc gctggcgctg gatacacctg
    73201 ctatttgctg taatggcacc tatttgtatg attatcatgc aaaaaccgtg ctggaagcgg
    73261 acccaatgcc cgttaataaa gccctgcaac tcattgagat gctgaatgaa caccacattc
    73321 acggtctgat gtatgtggat gatgcgatgg tctatgagca cccgaccgga catgtcattc
    73381 gcacgtctaa ctgggcgcaa accctgccgc cggaacagcg tccgactttc acacaagtcg
    73441 cttctctggc tgaaacggcg caacaagtta acgccgtatg gaagttcgcc ctgacgcacg
    73501 atgacctgcc gcaattgcag cattttggta agcatgtcga acatgaactg ggactggagt
    73561 gtgaatggtc ctggcacgat caggttgata ttgcacgcgg cggcaacagc aaaggtaaac
    73621 gtttgacgaa atgggttgag gcgcaaggct ggtcgatgga aaacgtcgtg gcgttcggcg
    73681 ataacttcaa tgatattagt atgctggaag ccgctggtac aggcgtggcg atgggcaacg
    73741 ccgatgacgc agtaaaagcg cgcgccaaca ttgtgattgg tgataacacc accgacagca
    73801 ttgcccagtt catttatagc cacctgattt aatcaggcgg ttatcgacac acttttaatt
    73861 tgcgcataca gccacaggcc aggtttgatc gccagttcat ccctggccca cgggctgata
    73921 cgcgcccaca gcgttttaca gccgacttcc agctccactt ccacctggcc gttgtcgtca
    73981 taactattaa caacttttgc ccgcaatacg ttacgaatgc tggtttgctg cggcggttgt
    74041 aaaaccagtg agacatcgga agcctgaatg cggatgcgta gcgcagcttg cagcggttcg
    74101 tccagcttat tgacccacaa atgctgatcg cccagcgcca gcgcggtcat cgcgtaatgc
    74161 ggatgatgct caagtactgt cactttcaga atgctacttt gttgctcttt cggtagccac
    74221 ggattcatca cgctactacc ccagacttct tccagcgcgc caaaggcttt cacctgaccg
    74281 ttttccagta ccatcactct gtctgccaga tggaggatct catccagcga atggctgaca
    74341 tacaacatcg gaatgttgat ttcccgcgtc agacgttgca gataaggcaa cagttcgcgt
    74401 ttacgcggaa tatccagtga tgccagcggt tcatccagca acagcaattc cggtgctgtc
    74461 agcaaagccc gaccaatcgc cacgcgctgt ttttcgcctc cggacaggct gcctggtaaa
    74521 cgatcaagca acggttcaat gcctaaaagc gccaccagct tatcgaactg attgaccatg
    74581 cttttcgcca tgccgtagcg caaattgcca cgcactttat aatgcggaaa cagccgcgca
    74641 tcctgaaaca catagcctac gcgacgcttt tctggcgtca ggcagatacc tttatcggcg
    74701 tcatttagta cccgaccatt gaggacaatc cgcccttttt gcggacgtgt cagcccactg
    74761 atggcgttaa tcagcgaggt ttttccggca ccagagacac caaaaatagc ggtgatgcca
    74821 ttggcgggca gcgtttcatt aatcgtcagg caatggttgc ccaacgtctg ggaaaaattc
    74881 agttccagca tgattagcgc cccgcccgct cacggctgat tctggccagc cattctgaaa
    74941 tcaacaggga gatcatcgcc agcgcaatag aaataataca cagtctcgcc gcgccacttt
    75001 ccccgccagg ggtctggatc agggtataca tggcagaagg aatggtccgc gtttcaccag
    75061 gaatgttcga cacaaaggtg atggttgcgc caaattcacc gagcgaacga gcgaatgcca
    75121 gtaccgtacc aacaataatt cccggtaagg tcagcggtaa cgtgatagta aagaaaacgc
    75181 gccagcgccc ggcccccagt gttcttgcgg cctgctccag tttgatatca acaccttcca
    75241 gcgccagacg aatcgcccgc accatcagcg gaaaagacat gacagcggca gcgagaaccg
    75301 caccacgcca gctaaacgcg aaagaaagac caaaccagtc atacagacgt tcaccgataa
    75361 atccgcgccg tcccatcgaa actaataata ggtaaccgac gaccacgggc ggtaacacca
    75421 gcggtagatg cagtacgctg tcgagcagag ctttgcccgg aaacgtgcaa cgtaccagta
    75481 accaggcaaa aaagatccca aacggcaggc taaacagcac agccagggaa gaaactttca
    75541 ggcttaataa aactgcctgc cattctggat cggtcagtat cattacttgg ttgtaaatcc
    75601 gtaacgttta aagatttccg cagcctgcgg ccccttcaga taatcataaa atgctttcac
    75661 tgtcgcattg ttatgccctt ccacaacagc aaccggatat tccacttttt tatgtgaatc
    75721 ttccgggaag gtggcaacca cttttacccc tttgctggca actgcgtcag aaccgtaaac
    75781 aatacccagc ggcgcttcat tgcgttcgac caacgccagc gcgccacgaa catcttccgc
    75841 cggagccagt ttcggggaaa gcgtatccca tgcgcccagt ttttgcagtg cttctttcgc
    75901 ataaatgcca gcagggacat gttccggatc accaaccgcg aggcgaccgc cattcagcag
    75961 cgaagtccag ttggttttgc tgtcgatggt gaaatctttc tgctcgctgg ctttcggtgc
    76021 tacaacgacc aggctattgc cgagcagtgt ctggcgcgaa gccgtatcga tcgctttttt
    76081 atcaaccgca taatccatcc atttctgatc ggcagaaata aacagatccg caggcgcacc
    76141 cgcttcaatc tgacgggcca aagtagatga cgaagcgaaa gaagaaacca catccacgcc
    76201 tttctctttt ttatactgcg tagcaatgtc ctgcattgcg ttagtcagtg atgcggcggc
    76261 gaacaccgtg attttccctt catctgccag tgcattgcca gcaacagcga aagagagtgc
    76321 cgccccggta aacaagttca accatttacg agccattggt aaccccttaa tctaacgtta
    76381 tgtaggcgtc aatataacgg caagttcgga attttcccag cagttattgc taacctttgt
    76441 gaggtagatg agaaaaaata tcggcagaaa aagcaggaag ttgagaaaaa gaaaatgccc
    76501 gactaagcgg gcattcaggg aatcaatgat tttgtccggg ctggtctttt ttaccaacac
    76561 cagaaaagat gttgaatact tcaccaagac cgtaaatcag acccaggatg atggccatca
    76621 cgacaggtac catgattacg gcgaatacca gactttttaa taactctaac atggtcaact
    76681 ccagatatag tcatgagact attctaaccg ctaagcacag aaaagcactc cccttttgtg
    76741 cggtcagctt tgcgtggcgt tcgttttccg tcacaataag acttttgcca ggacattgtt
    76801 atgcaggccg aaatccttct cacccttaag ctccaacaaa aattattcgc cgacccgcgc
    76861 cgcatttcgc tactaaaaca cattgcgctt tccggttcca ttagccaggg agcgaaagat
    76921 gccggtatca gctataaaag cgcctgggat gccattaacg agatgaatca gttaagtgag
    76981 catattctgg ttgagcgcgc aacaggcggt aaaggtggag gcggcgcagt actgacccgc
    77041 tatggtcagc gactgattca actctatgac ttactggcgc aaatccagca aaaagccttt
    77101 gatgtgttaa gtgacgatga cgccctgccg ctgaacagcc tgctggccgc gatctcacgt
    77161 ttttcactgc aaaccagcgc ccgtaaccag tggttcggta ccatcaccgc tcgcgatcat
    77221 gatgacgttc aacagcatgt tgatgtctta ctggctgatg gaaaaacacg cctgaaagtc
    77281 gcaattaccg cacaaagcgg cgcgcgtctg gggctggatg aaggcaaaga agtgttgata
    77341 ttgctaaaag cgccgtgggt aggtattact caggacgagg cggtcgcgca aaacgctgac
    77401 aaccaattac cgggtattat tagtcatatt gagcgcggcg cagagcagtg cgaagtatta
    77461 atggcgctac ccgacgggca aacactgtgc gccacagtgc cggtaaatga agcgacttct
    77521 cttcagcaag ggcagaatgt cacggcctac tttaatgccg acagcgtgat tatcgccacg
    77581 ctgtgctaag cgtgttgaca atttgttatg aaacacgtat ccctgtcagt aatcgctgca
    77641 caaaatggga tataaaatgt catcgttgca aattttgcaa ggcacgtttc gtcttggcga
    77701 cacaaaaacg ctgcaattgc ctcggctaac gttaaacgcg ggtgatagtt gggcgtttgt
    77761 cggttcgaat ggaagcggga aatcggcgct ggcccgcgcg ctgtcggggg aacttccgct
    77821 tttgaaaggt gaacggcaaa gccagttttc ccacatcact cgtctctcct tcgagcaatt
    77881 gcaaaagctc gtcagcgacg aatggcagcg gaataacacc gatatgctta gtcctggcga
    77941 agatgacacc gggcgtacca cggctgagat cattcaggat gaagtaaagg atacttcgcg
    78001 ttgcatgcaa ctggcgcagc agttcggtat taccgccctc ctcgaccgac gctttaaata
    78061 cctttccact ggcgagacgc gaaaaaccct gctgtgtcag gcgctgatgt cggagcctga
    78121 cttgttgatc cttgatgaac cgtttgatgg cctggatgtt gcctcacgtc agcatctggc
    78181 tgagctactc gcctcgttac atcagtccgg tattactctg gtactggtgc tcaatcgctt
    78241 cgatgagatc ccggaatttg tccagtttgc tggcgtgctg gcggattgca cgttagcgga
    78301 aactggcgct aaagaagaac tgctccaaca agcactcgtt gcgcaactgg cgcatagcga
    78361 actgcttgaa ggtgtgcaaa tgccggagcc ggatgaacct tcagcacgtc acgccttacc
    78421 cgccaacgaa ccgcgcattg tgctgaacaa tggcgtggtt tcttataacg aacgccccat
    78481 ccttaataac cttagctggc aggtgaatcc aggcgaacac tggcaaattg tcgggccaaa
    78541 tggcgcggga aaatcgacgt tattaagcct gattactggc gatcatccgc aaggttacag
    78601 caacgatttg acgcttttcg gacgacgtcg cggcagcggc gaaaccatct gggatatcaa
    78661 aaagcatatc ggttacgtca gcagtagttt gcatctggat taccgggtca gcactactgt
    78721 gcgtaatgtg attctttctg gctattttga ttcgattggc atttatcagg ccgtttcgga
    78781 tcgccagcaa aaactggtgc agcagtggct ggatattctc ggcattgata aacgcacggc
    78841 tgacgctcct ttccatagtc tttcctgggg acagcagcgt ctggcgctga ttgtccgcgc
    78901 actggtgaaa catccgacgt tgcttattct cgatgaacca ctacaggggc ttgatccgct
    78961 caatcgccag cttatccgcc gttttgttga tgtgctgatt agcgaaggtg aaacgcaatt
    79021 gttgtttgtt tcgcaccacg ctgaagatgc gcctgcctgt attacccatc gtcttgagtt
    79081 cgtgccggac ggtggactct atcgctatgt gctgacaaaa ataaattgag tcggtaatgc
    79141 tgaccgtgcc ggaggcggcg taaacgtgtt atccggccaa cggtttgacg catccaggca
    79201 tgaaaccgcg tctttttttt cagataaaaa gcgcaatcat tcataaagcc gctgttttat
    79261 aatcacttaa tcgcgcataa aaaacggcta aattcctgtg taaacgattc cactaattta
    79321 ttccatgtca cacttttcgc atctttgtta tgctatggtt atttcatacc ataagcctaa
    79381 tggagcgaat tatgagagtt ctggttaccg gtggtagcgg ttacattgga agtcatacct
    79441 gtgtgcaatt actgcaaaac ggtcatgatg tcatcattct tgataacctc tgtaacagta
    79501 agcgcagcgt actgcctgtt atcgagcgtt taggcggcaa acatccaacg tttgttgaag
    79561 gcgatatccg taacgaagcg ttgatgaccg agatcctgca cgatcacgct atcgacaccg
    79621 tgatccactt cgccgggctg aaagccgttg gcgaatcggt acaaaaaccg cttgaatatt
    79681 acgacaacaa tgtcaacggt actctgcgcc tgattagcgc catgcgcgcc gctaacgtca
    79741 aaaactttat ctttagctcc tccgccaccg tttatggcga tcagcccaaa attccatatg
    79801 ttgaaagctt cccgaccggc acaccgcaaa gtccttacgg caaaagcaag ctgatggtgg
    79861 aacagatcct taccgatctg caaaaagccc aaccggactg gagcattgcc ctgctgcgct
    79921 acttcaaccc ggttggcgcg catccgtcgg gtgatatggg cgaagatccg caaggcattc
    79981 cgaataacct gatgccgtac attgcccagg ttgctgtagg ccgtcgcgac tcactggcga
    80041 tttttggtaa cgattatccg accgaagacg gcactggcgt gcgcgattac atccacgtaa
    80101 tggatctggc agatggtcac gtcgtggcga tggaaaaact ggcgaacaag ccaggcgtac
    80161 acatctacaa cctcggcgca ggcgtaggca gcagcgtgct ggacgtagtt aatgccttca
    80221 gtaaagcctg cggcaaaccg gttaactatc attttgcacc acgtcgcgcg ggcgaccttc
    80281 cggcctactg ggcggacgcc agcaaagccg accgtgaact gaactggcgc gtaacgcgca
    80341 cactcgatga aatggcgcag gacacctggc actggcagtc acgccatcca cagggatatc
    80401 ccgattaagg aacgaccatg acgcaattta atcccgttga tcatccacat cgccgctaca
    80461 acccgctcac cgggcaatgg attctggttt caccgcaccg cgctaagcgc ccctggcagg
    80521 gggcgcagga aacgccagcc aaacaggtgt tacctgcgca cgatccagat tgcttcctct
    80581 gcgcaggtaa tgtgcgggtg acaggcgata aaaaccccga ttacaccggg acttacgttt
    80641 tcactaatga ctttgcggcc ttgatgtctg acacgccaga tgcgccagaa agcaacgatc
    80701 ctttgatgcg ttgccagagc gcgcgcggta ccagccgggt gatctgcttt tcaccggatc
    80761 acagtaaaac gctgccagaa ctgagcgttg cggcattgac ggaaatcgtc aaaacctggc
    80821 aggagcaaac cgcagaactg gggaaaacat acccgtgggt gcaggtcttt gaaaacaaag
    80881 gcgcggcgat gggctgctct aacccgcatc cgcacggaca gatttgggca aatagcttcc
    80941 tgcctaacga agctgagcgc gaagaccgtc tgcaaaaaga atatttcgcc gggcagaaat
    81001 caccaatgct ggtggattat gttcagcgcg agctggcaga cggtagccgt accgttgtcg
    81061 aaaccgaaca ctggttagcc gtcgtgcctt actgggctgc ctggccgttc gaaacgctac
    81121 tgctgcccaa agcccacgtt ttacggatca ccgatttgac cgacgcccag cgcagcgatt
    81181 tggctctggc gttgaaaaag ctgaccagtc gttatgacaa cctcttccag tgctccttcc
    81241 cctactctat gggctggcac ggcgcgccat ttaatggcga agagaatcaa cactggcagc
    81301 tgcacgcgca cttttatccg cctctgttgc gctctgccac cgtacgtaaa tttatggttg
    81361 gttatgaaat gctggcagaa acccagcgag acctgaccgc agaacaggcc gcagagcgtt
    81421 tgcgcgcagt cagcgatatc cattttcgcg aatccggagt gtaagaaatg agtctgaaag
    81481 aaaaaacaca atctctgttt gccaacgcat ttggctaccc tgccactcac accattcagg
    81541 cgcctggccg cgtgaatttg attggtgaac acaccgacta caacgacggt ttcgttctgc
    81601 cctgcgcgat tgattatcaa accgtgatca gctgtgcgcc acgcgatgac cgtaaagttc
    81661 gcgtaatggc agccgattat gaaaatcagc tcgacgagtt ttccctcgat gcgcccattg
    81721 tcgcgcatga aaactatcaa tgggcgaact acgttcgtgg cgtggtgaaa catctgcaac
    81781 tgcgtaacaa cagcttcggc ggtgtggaca tggtgatcag cggcaatgtg ccgcagggtg
    81841 cagggttaag ttcttccgct tcactggaag tcgcggtcgg aaccgtattg cagcagcttt
    81901 atcatctgcc gctggacggc gcacaaatcg cgcttaacgg tcaggaagca gaaaaccagt
    81961 ttgtaggctg taactgtgga atcatggatc aactgatttc cgcgctcggc aagaaagatc
    82021 atgccttgct gatcgattgc cgctcactgg ggaccaaagc tgtttccatg ccgaaaggcg
    82081 tggctgtcgt catcatcaac agtaacttca aacgtaccct ggttggcagc gaatacaaca
    82141 cccgtcgtga acagtgcgaa accggtgcgc gtttcttcca gcagccagct ctgcgcgatg
    82201 tcaccattga agagttcaac gctgttgcac atgaactgga cccgatcgtc gcgaaacgcg
    82261 tgcgtcacat cctgactgaa aacgcccgca ccgttgaagc tgccagcgcg ctggagcaag
    82321 gcgacctgaa acgtatgggc gagttgatgg cggagtctca tgcctctatg cgcgatgatt
    82381 tcgaaatcac cgtaccgcaa attgacactc tggtagaaat cgtcaaagct gtgattggcg
    82441 acaaaggtgg cgtacgcatg accggcggcg gatttggtgg ctgtatcgtc gcgttgatcc
    82501 cggaagaact ggtgcctgcc gtacagcaag ctgtcgctga acaatatgaa gcaaaaacag
    82561 gtattaaaga gactttttac gtttgtaaac catcacaagg agcaggacag tgctgaacga
    82621 aactcccgca ctggcacccg atggtcagcc gtaccgactg ttaactttgc gtaacaacgc
    82681 agggatggta gtcacgctga tggactgggg tgcgacttta ctttccgccc gtattccgct
    82741 ttccgatggc agcgtccgcg aggcgctgct tggctgcgcc agcccggaat gctatcagga
    82801 tcaggccgca tttctggggg cctctattgg tcgttatgcc aaccgcatcg ccaatagccg
    82861 ttataccttt gacggtgaaa ccgtgacgct ttcaccaagt cagggcgtca accaattgca
    82921 tggcggcccg gaagggttcg acaaacgtcg ctggcagatt gtgaaccaga acgatcgtca
    82981 ggtgctgttt gccctgagtt cagatgatgg cgatcagggc ttcccgggta atctcggcgc
    83041 gacggtgcaa tatcgtctga ccgacgataa ccgtatctcc attacttatc gcgccacagt
    83101 tgataaacct tgcccggtga atatgactaa tcacgtctat ttcaatcttg acggcgagca
    83161 gtctgacgtg cgcaatcata agttgcagat tctggcggaa gaatatctgc cggttgatga
    83221 aggcggcatt ccgcacgacg gcctgaaatc tgtcgccgga acctcttttg atttccgcaa
    83281 cgccaaaatc atcgccagtg agtttcttgc cgacgacgat cagcgcaaag tgaaaggtta
    83341 cgatcacgcg ttcttgttac aggccaaagg cgatggcaag aaagtggcgg cgcatgtctg
    83401 gtcagcagat gaaaaattgc agctgaaggt ctacaccacc gctccggctc tgcaattcta
    83461 ctccggcaac ttcctcggcg gcacaccgtc gcggggaacc gaaccttacg ctgactggca
    83521 agggctggct ctggaaagcg aatttctgcc ggacagcccg aaccaccctg aatggccgca
    83581 accggactgc ttcctgcgtc ctggcgaaga gtattccagc ctgacggaat atcagtttat
    83641 tgctcagtaa tgttaagccc tcgtcatgag ggctttatcc tcatattgtt caaatcacca
    83701 gcaaacaccg acatatttgc aactcaatat tcacaacaac cttacactgc gacactattt
    83761 tcgctatggt tatgcgtaag cattgctgtt gcttcgtcac ggcaatataa tgagaattat
    83821 tatcattaaa agatgatttg aggagtaagt atatggctgt aactaagctg gttctggttc
    83881 gtcatggcga aagtcagtgg aacaaagaaa accgtttcac cggttggtac gacgtggatc
    83941 tgtctgagaa aggcgtaagc gaagcaaaag cagcaggtaa gctgctgaaa gaggaaggtt
    84001 acagctttga ctttgcttac acctctgtgc tgaaacgcgc tattcatacc ctgtggaatg
    84061 tgctggacga actggatcag gcatggctgc ccgttgagaa atcctggaaa ctgaacgaac
    84121 gtcactacgg tgcattgcag ggtctgaaca aagcggaaac cgctgaaaag tatggcgacg
    84181 agcaggtgaa acagtggcgt cgtggttttg cggtgactcc gccggaactg actaaagatg
    84241 atgagcgtta tccgggtcac gatccgcgtt acgcgaaact gagcgagaaa gagctgccac
    84301 tgacggaaag cctggcgctg accattgacc gcgtgatccc ttactggaat gaaaccattc
    84361 tgccgcgtat gaagagcggt gagcgcgtca tcatcgccgc acacggtaac tcgttacgtg
    84421 cgctggtgaa atatctcgat aacatgagcg aagaagagat tcttgagctg aatatcccga
    84481 ccggcgtgcc gctggtttat gagtttgacg agaacttcaa accgctgaaa cgctattatc
    84541 tgggtaatgc tgacgagatc gcggcgaaag cagcggcggt tgctaaccag ggtaaagcga
    84601 agtaaacgtc attcgcttaa aaatgagaaa gccgactgca aaatgagtcg gcttttttat
    84661 ttttcgttgc taccaatgga gcgcattgcc tgatgcgacg ctgcgcgttt tatcaggcct
    84721 acggtgatta atcggatacg ccactctgac agcgcatccg acaattaaac tttacccgcg
    84781 acgcgctttt actgcattcg ccagttgacg taacagagca tcggtatcat cccagccaat
    84841 gcaggcatcg gtgatgctct taccgtaggc cagcggttcc ccgctctcga ggctctgatt
    84901 gccttccacc agatggcttt ccaccatcac gccaataatg gccttttcgc caccggcaat
    84961 ctgctggcaa acgtcagcac aaacatccat ctgctttttg aattgtttag acgagttagc
    85021 atggctgaaa tcgatcatca cctgtgctgg caggcctgct ttgttcagcc cttctttcac
    85081 ttcagcaacg tgcttcgcgc tgtagttagg ctctttaccg ccgcgcagaa tgatatggca
    85141 atcgccgtta ccgctggtat tcacaatcgc cgaatgaccc catttggtca ctgaaaggaa
    85201 gcagtgcggc gcaccggcgg cattaatggc atcgatagcc actttaatcg taccatcagt
    85261 gccatttttg aagcctaccg ggcaagaaag ccctgaagcc agttcgcggt gcacctgcga
    85321 ttccgtagta cgtgcgccaa ttgcgcccca gctcatcagg tcagcgagat attgtggggt
    85381 gatcatatcg agaaactcac ccgccgctgg cagaccgctg tcgttaatat caagcaacaa
    85441 tttacgggca atacgcagac cgtcgttgat ctggaagctg ttatccatat gcggatcgtt
    85501 aatcagccct ttccagccca ccgtggtacg cggcttttca aaatagacgc gcattacgat
    85561 ttccagctca tctttcagct cttcacgcag cgccagcaag cgagtggcat actctttagc
    85621 cgcgacagga tcatgaattg agcatgggcc aatcaccacc aacaggcgat catcattacc
    85681 tttcaggatc ttatggatcg cttttcgggc atgggcgacc gtattcgcgg cattttcagt
    85741 agcggggaat ttttccagca atgcgacagg aggaagtaac tctttgattt ctttgatgcg
    85801 taaatcgtcg ttctgataat tcatgtctgt tccagtgttg ccatacttat cttagtgaat
    85861 gcaatacttc caatctatat cttccgtcag aatgtgtaaa cggggtttta cactatgaac
    85921 ggattaatcc tggaattagc aagaaaaacg ccagattgtc gcgaaaaacg agatctctcc
    85981 tacaatttct aactgtaact cctttgtttg ttaattattt caagattctc tgctgggtat
    86041 ctttgcctgg ctgaaatctt aaaccattgc cttatattca cctgcaaatg cactgttgga
    86101 agaggttatc cgacataacg accataacag gagcatccta tgaaaatgac aaaactggcc
    86161 acactatttt tgactgccac tctaagcctt gccagcggtg ccgcactggc tgccgatagc
    86221 ggagcgcaaa ctaataacgg ccaggcaaac gccgccgctg atgcgggcca ggtagcccct
    86281 gatgcccgtg aaaatgtcgc gccaaataac gtcgacaata acggggtaaa taccggttct
    86341 ggcggcacaa tgctgcatcc ggatggttct tcaatgaaca atgacggcat gaccaaagat
    86401 gaagagcaca agaacaccat gtgcaaagat ggtcgctgcc cggatatcaa taaaaaagtc
    86461 caaaccggtg atggcatcaa caatgatgtc gataccaaaa ccgacggtac cacgcagtaa
    86521 ccctgcgaaa tagccaataa tgggagagcg tagtctctcc cttttaattt ttcccttcta
    86581 aaagcagtat gatgtcataa agttaagtga gaataattaa gggatgactc gtcatggcgc
    86641 actcacactc acacacttcc tcacacctgc cagaagataa taatgctcgt cgcttgttgt
    86701 atgctttcgg cgtgactgcc gggtttatgc tcgtagaagt cattggtggt tttctttccg
    86761 gttctctggc attgctggcc gatgcgggtc atatgttgac cgatactgcc gccctgcttt
    86821 tcgccctact cgcagtgcaa ttttcccgtc gtcctcccac cattcgccac actttcggtt
    86881 ggctaagatt gaccacgctc gcggcgtttg tgaatgccat cgccctggtg gtgattacta
    86941 ttttgattgt ctgggaggcg atagaacgct tccgcactcc gcgtccggtc gagggcggca
    87001 tgatgatggc aattgccgtg gctgggctgc tggcaaatat actttctttc tggttacttc
    87061 atcacggcag cgaagagaaa aacctcaacg tgcgagcagc ggcactgcat gtgctcgggg
    87121 acctgctggg ttcggttggg gctattattg ccgcgttgat tattatctgg accggctgga
    87181 cacctgctga ccccattctc tcaatactgg tgtcgcttct ggttctgcgt agcgcgtggc
    87241 gactgttgaa agatagtgtg aatgaattac ttgaaggtgc accggtatcg ctggatatcg
    87301 ctgaactgaa gcgtcgcttg tgccgggaaa tcccggaagt ccgcaatgtg caccatgtgc
    87361 atgtatggat ggtaggcgag aagccggtga tgacgctgca tgtgcaggtg atcccgccac
    87421 acgatcacga tgccttgttg gatcagatcc aacactacct gatggatcac tatcagattg
    87481 agcacgccac cattcagatg gaatatcaac cttgtcatgg gccagactgc cacctgaata
    87541 gaggggtgtc tggccattca catcatcatc attaatggga cagcgcacgt gaacctcttt
    87601 cgcgtgcgct tttgatccac atccggctgc cgttgagggc aataaaggtc aggatgatgt
    87661 actccagaga catggcgtaa acgccctgaa gtgcaaaaat aacgacgcta atcacgttaa
    87721 taatcaccca caacagccag ttttccacat acttacgtgt catcagaatc attgccacga
    87781 tagataacac catcatgcat gaatcccaga acgggaaagc gtccggctgt agttcaggca
    87841 tcgcaacctg taatcctaat gcttgcatga tcatgactgc cacgcgggtc aaaaatgcaa
    87901 acacaggatt gataaatacc gtcattagac caatcgaaac aacgcaaacc gccagccagc
    87961 ttagcgcctt cggcaatggc aaccagcgaa ttttcaactc cgcctcgttc tgactggttt
    88021 gtcgcgacca cgcataccag ccgtaaatat tcgcggcaaa gaaaaacacc tgtaataaca
    88081 ggctggcata cagctgaatc tgaaagaaaa taatgccaaa caaggtgacg ttgatcaggc
    88141 caaagaagta gttactgatc ttctccagac tggcaaggcc aatacacagc aacccggcga
    88201 tcgtgcctac cgcttcgatc catgagagat cataaccgcc tgcccctatt ggtatatgta
    88261 ccaggatatt ctgcacacta aaaaaatcca tcgttccccc aaagcgtaat gtgacgcctt
    88321 attatcaatt atccacgtag tgtagccgca aaatccagca tacgattgag cggcaccagc
    88381 gccctctctc gcagcctttc atcaacataa acctcgtgat tgcttccttc cagttctaat
    88441 gcctctgcga tggcctgaag gccattcatg gccatccacg gacaatgcgc gcagctgcga
    88501 caggttgcgc cctcacccgc ggttggtgct tccagtaact ctttatctgg caccgcctgc
    88561 tgcattttgt agaaaatgcc ccgatcggtt gccacgataa gccgctgatg ttgcaatgtt
    88621 ttcgcagcag cgatcagttg actggtggaa ccgaccgcat ccgccatctc tacaatagct
    88681 tgcggtgatt ctggatgcac cagtatggca gcatccgggt attcttcttg caagcgggtt
    88741 aacgcctgag tcttaaactc atcatgcaca atgcaggcac cctgccagca taaaatgtct
    88801 gcgcccgtct gtttttgcac gtaacgcccc agatgtttgt caggtgccca gatgattttt
    88861 tcacccaaac tatccagatg atcaataagt tcgacggcaa tgcttgaagt taccacccaa
    88921 tctgcgcgcg cttttaccgc agcagaagtg ttggcgtaga cgacgacagt acgatcggga
    88981 tgggcatcgc aaaatgcgtt aaattcttca acagggcagc cgagatccag tgaacattca
    89041 gcctgaagtg tcggcatcag aattgttttt tccggactga gaattttggc ggtttctccc
    89101 ataaatctca ccccagcgac tagcaacgta gaagcgggat gctttgcacc gaagcgcgcc
    89161 atttccagag aatcagaaat acagccaccg gtttcttctg ccagttgttg aatttcggga
    89221 tcggtatagt agtgggcaac catcaccgca ttacgttctt ttagtagacg ttttatcttc
    89281 tcgcggtaat tcgctttttc atcaatgctt aacggcgtcg gcttcggggg gaaaggataa
    89341 atcgccgtgt ctggatcaaa catcacgctc atcttaccat ctcgttctac aggcttaacg
    89401 ttaaaaccga cttaagcgtg atattcgcta ttatcggcgt aatttgtttt atatactaaa
    89461 caagatagtc gaatggtggg gaaaagtcac tcgaattacg tatgagatgc cgaatgccac
    89521 actttgcgtc ttattcctcc gacgtagagt tgtttacgca gcaaacgcgg agtatgtcat
    89581 cagggtcaag aattgaaatt gagagatgcc tgaatagcaa aaaaacgcct ttagggcgct
    89641 tttttgcatt ggtgggtcgt gcaggattcg aacctgcgac caattgatta aaagtcaact
    89701 gctctaccaa ctgagctaac gaccccttgc gggattatgc tgctttaatc attcaggatg
    89761 gtgggtcgtg caggattcga acctgcgacc aattgattaa aagtcaactg ctctaccaac
    89821 tgagctaacg acccatacgg gtgttacctg aaagatttct actcggaacc aatgtttaaa
    89881 attggtgggt cgtgcaggat tcgaacctgc gaccaattga ttaaaagtca actgctctac
    89941 caactgagct aacgacccga gtggtgggtg atgacgggat cgaaccgccg accccctcct
    90001 tgtaagggag gtgctctccc agctgagcta atcacccgat actgcgctgg atactacaaa
    90061 ctacttccac cgaacccacc gtaatcagtg gtgggtcgtg caggattcga acctgcgacc
    90121 aattgattaa aagtcaactg ctctaccaac tgagctaacg acccggtggt gggtgatgac
    90181 gggatcgaac cgccgacccc ctccttgtaa gggaggtgct ctcccagctg agctaatcac
    90241 ccgatactac gctggatact acaactaact atgttagtgg tgggtcgtgc aggattcgaa
    90301 cctgcgacca attgattaaa agtcaactgc tctaccaact gagctaacga cccacttttt
    90361 cgttgctttc ggtttgtttg atatcccgtg gcaacggcgg catatattac tgatttcaga
    90421 cttgagcgca acaaaaattt cgatgtagat cactcaactg cttatgattc gcacgacacg
    90481 accagaaata atgcgacttc tggtcgtgtg ttatgcatta catcgcgttc agacgttttt
    90541 gcgcctgttt agcgccatca gtaccagggt atttactgat aacctgctgg tatacggctt
    90601 tcgcttttgc ggtgtcacct ttgtcctgca tgatgacgcc gactttaaac atcgcatctg
    90661 cagccttcgg tgacttcgga tagtttttca ctaccgaagc aaaataatac gccgcatcat
    90721 cttttttacc cttgttgtag tttaactgac ccagccaata attggcgttt ggcaggtaag
    90781 ttgaatcagg gtaatttttg atgaaattct gaaatgccac cattgcgtca tcctggcggg
    90841 atttatcctg caccagcgca atagctgcat tgtaatccgt gtttgcatca ccgcttttca
    90901 ccggcgcgcc agcattcgaa gtaccagcat cagctgtcgg cgtcgttgat gccaccacac
    90961 cgctttgatc gccgctggtt gattgcgccg ctgcaccacc gctgctgagg ctgtcgatct
    91021 gcaacaggat ctgcttttgc cgctccacga cctgattcag ttgatactga ttttcctgaa
    91081 tctgaccacg cagggaatca atatcggatt gattatcaga gagttgttgc tggagttggg
    91141 ttaaaagctg gctgtgagca ttagaaatac gctcaagttg agtgacgcgg tcttcgaccg
    91201 agcctgagcc gacactactg attggtgcct gagcaaaagc ggcccagggg gccgctatac
    91261 caaccagtaa cgacagactc aatagttgat gtctgaagtt actgctcatg caattctctt
    91321 agtaaaccag taccgcacga cggtttttgg catacgccgc ttcgtcatga cccagtactg
    91381 caggtttttc tttaccgtaa gaaacgatgg agatctggtc agcagaaacg cctttaccct
    91441 gcagatacat cttaacagcg ttcgcacgac gttcacccag ggagatgttg tattccggag
    91501 taccacgttc gtccgcgtga ccttctacgg tgactttgta agacgggttg ctacgcagga
    91561 agtttgcgtg tgcatccagc atttgagcga agtcagaacg gatatcgtac ttgtccagat
    91621 cgaagtaaac gatgttgttc tgctgcagct gttgcatttg cagacgagcc tgctcttcgg
    91681 aagacatgtt gccgttgccg ccgttcgcat ccataccagt gccggcaccc agcatgcctt
    91741 cgctgccgtc attgctggcg ttcttgttgg aagaacatgc cgcaattgcc ataacaggca
    91801 gagcaatcat cagccctttc agcactttgt tcagttgcat ttcaatgatt cctttactat
    91861 tcaattaatt attatcacag atacggcgac caggcaggga atttgacctg tccatcagtt
    91921 gccggaagac gcgctttgaa acgcccatct gtagaaacca aattcagcac ggatcccatc
    91981 ccctgagaag agctgtagat taccatagtg ccgttaggtg ccagacttgg cgtttcatcc
    92041 aggaacgtgg acgacagaac ttgtacgcct cccgttgcca gatcttgttt ggcaatgtgc
    92101 tgctgcccac cgttggagct gaccattacc ataaatttac cgtcgctgct gacatccgca
    92161 tcctggttct gcgaaccttc ccaggtaata cgttgtggcg caccgccgtt gatattcact
    92221 ttataaacct gcggacgacc ggcctggtca gaagtaaatg ccaggttctg gctgtccggg
    92281 aaccaggtcg gttcggtatt gttactgcga ccatcagtta cctggcggat ctgaccagaa
    92341 gccaaatcca ttacgtacag gttcaggcta ccggttttcg acaaggcgaa tgccagtttg
    92401 ctgccgtctg gcgagaatgc aggtgcaccg ttgtgacgcg ggaatgaagc cacctgacgt
    92461 acagcgccat ttgccagcgt ctgaataacc agcgcggaac gaccgctttc gaaggtcaca
    92521 taagccagtt tagaaccgtc tggtgaccac gccggagaca tcagcggttg cggtgaacgg
    92581 tgaacgacaa actggttgta accgtcatag tcagatacgc gcagttcata cgggaactga
    92641 ccgccgttag tctgaacaac gtaggcaata cgggtacgga acgcaccttt aataccggtc
    92701 agtttttcaa atacttcgtc actggcggta tgaccagcat aacgcagcca ctgcttgttc
    92761 actttgtacg agttctgagc aagtacagta cccggtgcgc cgccagtgtc aacaagttga
    92821 taagcaacat tgtaagaacc atccggattc ggagtgacct gaccgacaac cacagcgtca
    92881 atgcccagcg cggaccatgc agctggttgt acttcctgcg cactacccgg ctgctgtggc
    92941 agacgagcac gatctaacgg attaaattta ccgctgttac gcaagtcagc agcaacgatg
    93001 ccgccaatat cttcaggtgc cgcaccaggc cccgcccact ggaaaggaac aacaccaata
    93061 ggacgaccgg aatctacacc gctgtcgatc acaatgcgga cttcagcatg cagaactgat
    93121 gcccacagta tgagaaaacc aaatgctact cgtaatgcct gcttcatcat atctccctta
    93181 tctggaccga tggcccacga taatttagca gaatgttaac aaactaaaat acacaaaact
    93241 accagaaccc cgtggcaacc ggtgcctgat gttgaccgtc ggaacagtca acatcgcgat
    93301 tacggtttga agtccaatgg cgcgtttttg aacacttcat atactgcctg gcttggtggt
    93361 ttcgggatct tcgcaagttt agctgctgcc aacgcagctt gacaaagtgc gggatcgcca
    93421 ccttcaggtt tgatatccag taacatacca tcgggtgcca gttttatgcg cagcgtacag
    93481 gttttgcctg cataggacga tgcgtcatag aacttacttt cgatagcaga tttaatctgc
    93541 ccggcatagt tattgatatc ggcccctgat gcgccattgt ttttagtatt accactcccg
    93601 gcaggcgaag cattgttccc tttcgcccct ccccccgttt tcggtgcatt cttaccagag
    93661 cttagctcac cgaaaatatc atctgcctca gcggcagctt ttgctgcagc ggctttttca
    93721 gctgctgctt ttgccgctgc cgcttttttg tctgcggcgg ctttttctgc cgctgctttc
    93781 ttatcagctg c
//
LOCUS       DAPOXO010000005        93744 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPOXO010000005 DAPOXO010000000
VERSION     DAPOXO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 93744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.005"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            66..263
                     /locus_tag="ROH59_000495"
                     /pseudo
     CDS             66..263
                     /locus_tag="ROH59_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313209.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(361..2074)
                     /locus_tag="ROH59_000496"
                     /pseudo
     CDS             complement(361..2074)
                     /locus_tag="ROH59_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417861.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
     gene            2452..4074
                     /gene="pckA"
                     /locus_tag="ROH59_000497"
     CDS             2452..4074
                     /gene="pckA"
                     /locus_tag="ROH59_000497"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDX4803022.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            complement(4151..5503)
                     /gene="envZ"
                     /locus_tag="ROH59_000498"
     CDS             complement(4151..5503)
                     /gene="envZ"
                     /locus_tag="ROH59_000498"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HDX4803023.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
                     "
     gene            complement(5500..6219)
                     /gene="ompR"
                     /locus_tag="ROH59_000499"
     CDS             complement(5500..6219)
                     /gene="ompR"
                     /locus_tag="ROH59_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HDX4803024.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            6447..6923
                     /gene="greB"
                     /locus_tag="ROH59_000500"
     CDS             6447..6923
                     /gene="greB"
                     /locus_tag="ROH59_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312275.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HDX4803025.1"
                     /translation="MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHR
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP"
     gene            7020..9341
                     /locus_tag="ROH59_000501"
     CDS             7020..9341
                     /locus_tag="ROH59_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDX4803026.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLSYLRELEERRQAILKSISEQGKLTDDLANAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYIDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTV
                     PSHRALAMFRGRNEGILQLSLNADPQFEEPPKESYCEQIIMEHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREVQPAGNSAMMDALAAAMGKKR"
     gene            9779..10006
                     /gene="feoA"
                     /locus_tag="ROH59_000502"
     CDS             9779..10006
                     /gene="feoA"
                     /locus_tag="ROH59_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HDX4803027.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            10023..12344
                     /gene="feoB"
                     /locus_tag="ROH59_000503"
     CDS             10023..12344
                     /gene="feoB"
                     /locus_tag="ROH59_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HDX4803028.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQIASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            12355..12591
                     /gene="feoC"
                     /locus_tag="ROH59_000504"
     CDS             12355..12591
                     /gene="feoC"
                     /locus_tag="ROH59_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HDX4803029.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLKQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLHEWWALR"
     gene            12858..13220
                     /locus_tag="ROH59_000505"
                     /pseudo
     CDS             12858..13220
                     /locus_tag="ROH59_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(13249..14019)
                     /gene="bioH"
                     /locus_tag="ROH59_000506"
     CDS             complement(13249..14019)
                     /gene="bioH"
                     /locus_tag="ROH59_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HDX4803030.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGALSLADMAEVVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPDEFCHLLVALKQRV"
     gene            14057..14740
                     /gene="gntX"
                     /locus_tag="ROH59_000507"
     CDS             14057..14740
                     /gene="gntX"
                     /locus_tag="ROH59_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HDX4803031.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRAARTDKTLCPQCGLPA
                     THSHLPCGRCLQKPLPWQRLLTVADYAPPLSPLIHQLKFSRRSEIASALSRLLLLEVL
                     HARRTTGLQLPDRIISVPLWQRRHWRRGFNQSDLLCQPLSRWLHCQWDSEAVTRTRAT
                     ATQHFLNARLRKHNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAATV
                     QVWCLCRTL"
     gene            14799..15374
                     /gene="nfuA"
                     /locus_tag="ROH59_000508"
     CDS             14799..15374
                     /gene="nfuA"
                     /locus_tag="ROH59_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HDX4803032.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            15738..17054
                     /gene="gntT"
                     /locus_tag="ROH59_000509"
     CDS             15738..17054
                     /gene="gntT"
                     /locus_tag="ROH59_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDX4803033.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(17164..19248)
                     /gene="malQ"
                     /locus_tag="ROH59_000510"
     CDS             complement(17164..19248)
                     /gene="malQ"
                     /locus_tag="ROH59_000510"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HDX4803034.1"
                     /translation="MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVIVYTSGKKMPMVVEGSGEYSWLLTTEEGKQYKGHVTGGKAFNLPT
                     KLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYLANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDE
                     QMTAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMADPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKD
                     LDRRRRAAAKKK"
     gene            complement(19258..21651)
                     /gene="malP"
                     /locus_tag="ROH59_000511"
     CDS             complement(19258..21651)
                     /gene="malP"
                     /locus_tag="ROH59_000511"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HDX4803035.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRGNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWVKQCNPALAALLDKSLKKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQSDRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            22274..24979
                     /gene="malT"
                     /locus_tag="ROH59_000512"
     CDS             22274..24979
                     /gene="malT"
                     /locus_tag="ROH59_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HDX4803036.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTSDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFESAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV"
     gene            complement(25022..25441)
                     /locus_tag="ROH59_000513"
                     /pseudo
     CDS             complement(25022..25441)
                     /locus_tag="ROH59_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="catalyzes the conversion of terminal3'-phosphate of
                     RNA to the 2',3'-cyclicphosphodiester; incomplete; partial
                     in the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
     gene            25371..25808
                     /locus_tag="ROH59_000514"
     CDS             25371..25808
                     /locus_tag="ROH59_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005019152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX4803037.1"
                     /translation="MFCSCKEKLPASVAISRSATWRGNFRELSASVTRMATFATSGRI
                     TLDTVEDEINRLRYNWQESRPSTLTALLGAEAENIDLFDRMQLEHVIAICRQAKSLSA
                     AGRELFDISRQGKASVNDADRLRKYLARFGLTWEAMQDQHSSS"
     gene            complement(25790..26548)
                     /locus_tag="ROH59_000515"
     CDS             complement(25790..26548)
                     /locus_tag="ROH59_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HDX4803038.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDTMPPASVMQVLKDHHIQLELC"
     gene            complement(26565..27395)
                     /gene="glpG"
                     /locus_tag="ROH59_000516"
     CDS             complement(26565..27395)
                     /gene="glpG"
                     /locus_tag="ROH59_000516"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HDX4803039.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQSGHTDSGLHYRRYPFFAALRERAGPVTWVMMI
                     ACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            complement(27440..27766)
                     /gene="glpE"
                     /locus_tag="ROH59_000517"
     CDS             complement(27440..27766)
                     /gene="glpE"
                     /locus_tag="ROH59_000517"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HDX4803040.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHATQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            27956..29461
                     /gene="glpD"
                     /locus_tag="ROH59_000518"
     CDS             27956..29461
                     /gene="glpD"
                     /locus_tag="ROH59_000518"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HDX4803041.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYTWQARGLVNATGPWVKQFFDDGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLKVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGAISDLGEDFGHEFYEAE
                     LKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLMEYTQQRLSLAS"
     gene            complement(29515..30120)
                     /locus_tag="ROH59_000519"
     CDS             complement(29515..30120)
                     /locus_tag="ROH59_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000589351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803042.1"
                     /translation="MNKIRLYIYPVIFGFVIVPLLVWPTVIALAVLIFTLTFLAEIIF
                     SFPLLVVRISLQELQLELLVEYALFFSVMGGIGWQFSRRTPPELKNRLHCWLVFSPVY
                     FWLILSNFILYISPEKSALLENIRNFFLTFVWLPLNFSPFWPQPWTDFVGPISAQLGF
                     ALGYYCQWRSKNRSHRKKWGDWVTCLSLAILALGPLFNYLQ"
     gene            complement(30123..30890)
                     /locus_tag="ROH59_000520"
     CDS             complement(30123..30890)
                     /locus_tag="ROH59_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803043.1"
                     /translation="MHPTPAMQALIEQIYHIFRRYPAPQQFVVCCEYCLSQQEQKALR
                     NTSLRAIPYSLINAWNSSPGPDPQNSDEVRYFLPCLLEFVAQGQFDNIHEVFSLRRIN
                     LASKENWREDEREILQQFACQYMTDWVSGDEAVELQYKLEMFFRADIALSPLLDAIIS
                     VPGFWSAASLACLLNTYRDGYIRDNQDDIDKAITTQTNTWASNNQSILKERARQAIEN
                     PLKQSEQGTQYQAWEDEWMIDECLCAMYDASSESSGH"
     gene            complement(30993..32501)
                     /locus_tag="ROH59_000521"
     CDS             complement(30993..32501)
                     /locus_tag="ROH59_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDX4803044.1"
                     /translation="MMQSGKWILTSLVMTFFGIPILAQFLAAVVAMLGAGLAAILEVC
                     NLLFTPTIYLLLNVFMLTLGAIIIFFSGRVWAGDSAPEKREIAAWRQCFFLLPALLTL
                     VGWIIALHLADYQFRQMGSGWLANLMLSWQGVLLLSLISGDYWWIVIIPVGAHISFSL
                     GYGWPTRHPLTGTSGLRCRNLLLFLLLLLGFVAGYQAYLYKQLNPGVGVRENIDTWAW
                     RPDKLNNQLTPLRGKPQIQFTQNWPRLDGATAAYPIYASAFYALSVIPEDFHVWDYLD
                     NSRTQEAYNKIVNGDADIIFVAQPSDGQKKRAEKSGVTLLYTPFAREAFVFIVNADNP
                     VNSLTEQQVRDIFSGAITNWRAVGGDDQEIQTWQRPEDSGSQTVMLSQVMKNVRMISP
                     QETEVASVMEGMINVVAEYRNTKNAIGYTFRYYATQMNADKNIKLLAINGIAPTAENI
                     RNDKYPYIVDALMVTRENTTSETQKLVEWFLTPQGQSLVEDVGYVPMDKTLH"
     gene            complement(32626..35073)
                     /gene="glgP"
                     /locus_tag="ROH59_000522"
     CDS             complement(32626..35073)
                     /gene="glgP"
                     /locus_tag="ROH59_000522"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HDX4803045.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNDLQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADYIWHIDPVRL"
     gene            complement(35092..36525)
                     /gene="glgA"
                     /locus_tag="ROH59_000523"
     CDS             complement(35092..36525)
                     /gene="glgA"
                     /locus_tag="ROH59_000523"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDX4803046.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            complement(36525..37820)
                     /gene="glgC"
                     /locus_tag="ROH59_000524"
     CDS             complement(36525..37820)
                     /gene="glgC"
                     /locus_tag="ROH59_000524"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDX4803047.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPGKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            complement(37838..39811)
                     /gene="glgX"
                     /locus_tag="ROH59_000525"
     CDS             complement(37838..39811)
                     /gene="glgX"
                     /locus_tag="ROH59_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HDX4803048.1"
                     /translation="MTQLAIGKPTPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVIDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNDRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALME
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            complement(39808..41994)
                     /gene="glgB"
                     /locus_tag="ROH59_000526"
     CDS             complement(39808..41994)
                     /gene="glgB"
                     /locus_tag="ROH59_000526"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HDX4803049.1"
                     /translation="MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDAT
                     DVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETAS
                     LICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVIL
                     DWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALY
                     WIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQV
                     SGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLT
                     FGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKAMHELDFDPY
                     GFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTD
                     SMHYHGSNAGNGGAVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            complement(42267..43370)
                     /gene="asd"
                     /locus_tag="ROH59_000527"
     CDS             complement(42267..43370)
                     /gene="asd"
                     /locus_tag="ROH59_000527"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDX4803050.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELANPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            43562..44155
                     /gene="yhgN"
                     /locus_tag="ROH59_000528"
     CDS             43562..44155
                     /gene="yhgN"
                     /locus_tag="ROH59_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HDX4803051.1"
                     /translation="MNEIISATVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            complement(44201..45496)
                     /locus_tag="ROH59_000529"
     CDS             complement(44201..45496)
                     /locus_tag="ROH59_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312307.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDX4803052.1"
                     /translation="MDADSSDSTVTPGRLPDGLSSCPCFYLGKKLMNLSANAQATLLL
                     TSDFSRAAASEYKPLSNSEWGKFALWLKHQRISPAELLVPQPQEKLTGWSDPRISQER
                     ILGLLARGHSLALAVDKWQRAGLWILTRGDADYPVRLKNRLRTDAPPVLFGCGNKALL
                     QAEGMAIVGSRDAPTDDLRYTQQLAAKLAQQGICVISGGARGIDECAMASALEVGGTA
                     VGVLADSLLKTSTLVKWREGLIAGNLVLISPFYPEVRFTVGNAMARNKYIYCLAESAM
                     VVRAGMTGGTITGAMEALKHQWLPMQVKPNQDMQSANSRLVENGASWSAEQAENVTIR
                     LPDVPGLMYDRALRNAQPELFSLHEDDANYAVMPAHTPVDFYQLFVAELAILAKESIS
                     IERLASCTGLTIEQISVWLNRAEEEGRVIRLGEGHYQFR"
     gene            complement(45403..47499)
                     /locus_tag="ROH59_000530"
     CDS             complement(45403..47499)
                     /locus_tag="ROH59_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RecQ family ATP-dependent DNA helicase"
                     /protein_id="HDX4803053.1"
                     /translation="MEKHGAELLLQRMLSNTSATFREGQWEAIDAVVNQRRKLLVVQR
                     TGWGKSAVYFIASKIFRDRGAGPTIIISPLLALMRNQVAAAERLGITAETLNSTNREE
                     WQRISDKLLQGGVDCLLISPERLANQDFLETVLYPVADRIGLLVVDEAHCISDWGHDF
                     RPDYRRILDILRQLPANTPILGTTATANNRVVEDIRQQLGDIVIQRGTLARESLALDA
                     LVLGEQSSRLAWLATVIPQFSKSGIVYTLTTRDAELVAEWLRKNGISAFAYYSGVTCE
                     GAEDSNTAREYLEQALLANKIKVLVATTALGMGFDKPDLGFVIHYQMPGSIVGYYQQV
                     GRAGRAIDSAVGILLCGGEDRAIHQFFRESAFPAEAQIHEILNVLSENDGLTLRGIEQ
                     RTNLRYGQIEKALKLLVAENPSPVVYTEKLWRRTIVSFSPDHERINHLMNQRKSELAD
                     VESYITTKECKMQFLRRALDEPSAERCGKCSSCLQHPLLSPDIDSDLLHAANLFIKHA
                     DLPLNLNKQVASGAFTQYGFKGNLPAGLQGSTGRILSRWGDSGWGKQVAQEKKTGRFS
                     DELVEACAEMVRQRWNPHPEPTWVCCVPSLRHLDLVPDFARRLAAKLGLPFIDAIEKV
                     VDNPPQKMQQNRFHQCQNLDGAFVITPPLMPGPALLVDDIVDSAWTLTVLTALLRQAG
                     CPTVYPLALASTSVKN"
     gene            complement(47640..48980)
                     /gene="gntU"
                     /locus_tag="ROH59_000531"
     CDS             complement(47640..48980)
                     /gene="gntU"
                     /locus_tag="ROH59_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDX4803054.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRVH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(48984..49511)
                     /gene="gntK"
                     /locus_tag="ROH59_000532"
     CDS             complement(48984..49511)
                     /gene="gntK"
                     /locus_tag="ROH59_000532"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDX4803055.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RCNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(49650..50645)
                     /gene="gntR"
                     /locus_tag="ROH59_000533"
     CDS             complement(49650..50645)
                     /gene="gntR"
                     /locus_tag="ROH59_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HDX4803056.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSKSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(50738..51433)
                     /gene="yhhW"
                     /locus_tag="ROH59_000534"
     CDS             complement(50738..51433)
                     /gene="yhhW"
                     /locus_tag="ROH59_000534"
                     /EC_number="1.13.11.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="HDX4803057.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALVKDEQSVHQIAAERRIWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEILLFDLPPV"
     gene            complement(51556..52593)
                     /locus_tag="ROH59_000535"
     CDS             complement(51556..52593)
                     /locus_tag="ROH59_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDX4803058.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTI
                     AQAKELFALAKSKGLIVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITNGAPNYVKESEVLTNLEILERGFE
                     QASPSAVSLAR"
     gene            52927..53415
                     /gene="yhhY"
                     /locus_tag="ROH59_000536"
     CDS             52927..53415
                     /gene="yhhY"
                     /locus_tag="ROH59_000536"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX4803059.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYYNTLQVPHPSEQMWLER
                     LTARPGIKQLVACIDGIVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKFGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
     gene            complement(53476..55209)
                     /gene="ggt"
                     /locus_tag="ROH59_000537"
     CDS             complement(53476..55209)
                     /gene="ggt"
                     /locus_tag="ROH59_000537"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDX4803060.1"
                     /translation="MIKPTFLRRVAIAALLTGSCFSTVAAPPVSYGVEEDVFHPVRAK
                     QGMVASVDVTATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKN
                     GNTTAIDFREMAPAKATRDMFLDDQGNTDSKKSLTSHLASGTPGTVAGFSLALDKYGT
                     MPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDK
                     LVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLISKEDLAAYKAVERTPIS
                     GDYRGYQVYSMPPPSSGGIHIVQILNILENFDMQKYGFGSADAMQIMAEAEKYAYADR
                     SEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTTHYS
                     VVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPSVPNVYGLVGGDANA
                     VGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAEATNA
                     PRFHHQWLPDELRVEKGFSPDTIKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASD
                     PRSVDDLTAGY"
     gene            55329..55769
                     /locus_tag="ROH59_000538"
     CDS             55329..55769
                     /locus_tag="ROH59_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HDX4803061.1"
                     /translation="MKRLLLLTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQ
                     TQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGG
                     MLNSNRNPDSSLNQQHMLPERRNGDMLNQPSTPQPDIPLKTIGP"
     gene            complement(55756..56499)
                     /gene="ugpQ"
                     /locus_tag="ROH59_000539"
     CDS             complement(55756..56499)
                     /gene="ugpQ"
                     /locus_tag="ROH59_000539"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDX4803062.1"
                     /translation="MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAE
                     RCRKHGMMANIEIKPTTDTGPLTGKMVALAARELWTGMTPPLLSSFEIDALEAAQQAA
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNYKLLDKARVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(56496..57566)
                     /gene="ugpC"
                     /locus_tag="ROH59_000540"
     CDS             complement(56496..57566)
                     /gene="ugpC"
                     /locus_tag="ROH59_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol 3-phosphate ABC transporter ATP
                     binding protein UgpC"
                     /protein_id="HDX4803063.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTTGDIWIDRKRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVREPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLAGRVNNEGTHFELDGGIALPLNGGYRQYVGRKM
                     TLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGHWGEQKLVVRLAHQERPTAGS
                     TLWLHLPENQLHLFDGETGQRV"
     gene            complement(57568..58413)
                     /gene="ugpE"
                     /locus_tag="ROH59_000541"
     CDS             complement(57568..58413)
                     /gene="ugpE"
                     /locus_tag="ROH59_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HDX4803064.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQEVYAA
                     PMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            complement(58410..59297)
                     /gene="ugpA"
                     /locus_tag="ROH59_000542"
     CDS             complement(58410..59297)
                     /gene="ugpA"
                     /locus_tag="ROH59_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HDX4803065.1"
                     /translation="MPSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVTLFHDSYYLDAFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            complement(59395..60711)
                     /gene="ugpB"
                     /locus_tag="ROH59_000543"
     CDS             complement(59395..60711)
                     /gene="ugpB"
                     /locus_tag="ROH59_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HDX4803066.1"
                     /translation="MKPLRYTASALALGLALMANAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEARIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADIATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            complement(61108..61821)
                     /gene="livF"
                     /locus_tag="ROH59_000544"
     CDS             complement(61108..61821)
                     /gene="livF"
                     /locus_tag="ROH59_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HDX4803067.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRVQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            complement(61823..62590)
                     /gene="livG"
                     /locus_tag="ROH59_000545"
     CDS             complement(61823..62590)
                     /gene="livG"
                     /locus_tag="ROH59_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HDX4803068.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGMPLANGTPEQIRNNPDVIRAYLGEA"
     gene            complement(62587..63864)
                     /gene="livM"
                     /locus_tag="ROH59_000546"
     CDS             complement(62587..63864)
                     /gene="livM"
                     /locus_tag="ROH59_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HDX4803069.1"
                     /translation="MKPMHIAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASEIR
                     WQWVFIGTAVVFFFQLVRPAFQKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTLFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAVLLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            complement(63861..64787)
                     /gene="livH"
                     /locus_tag="ROH59_000547"
     CDS             complement(63861..64787)
                     /gene="livH"
                     /locus_tag="ROH59_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HDX4803070.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMLGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            complement(64835..65944)
                     /gene="livK"
                     /locus_tag="ROH59_000548"
     CDS             complement(64835..65944)
                     /gene="livK"
                     /locus_tag="ROH59_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HDX4803071.1"
                     /translation="MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQYIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENID
                     FVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYD
                     QDPTNQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA
                     NTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
     gene            66367..66750
                     /gene="panM"
                     /locus_tag="ROH59_000549"
     CDS             66367..66750
                     /gene="panM"
                     /locus_tag="ROH59_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HDX4803072.1"
                     /translation="MKLTIIRLENFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADAGV
                     EDRGVMTAFMRALGFTAQQGGWEKR"
     gene            complement(66747..67274)
                     /locus_tag="ROH59_000550"
     CDS             complement(66747..67274)
                     /locus_tag="ROH59_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX4803073.1"
                     /translation="MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKIL
                     RAYILCRNTPERQVLGYYTLSGSCFERAALPSKSKQKKIPYKNIPSVTLGRLAIDRSL
                     QGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
                     FFPTKSIELLFTPDD"
     gene            complement(67281..67547)
                     /locus_tag="ROH59_000551"
     CDS             complement(67281..67547)
                     /locus_tag="ROH59_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HDX4803074.1"
                     /translation="MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRA
                     AEVIEQHRRMILTEESWTRVMDALSNPPSPGEKLKRAAKRLQGM"
     gene            complement(67696..68799)
                     /gene="livJ"
                     /locus_tag="ROH59_000552"
     CDS             complement(67696..68799)
                     /gene="livJ"
                     /locus_tag="ROH59_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
                     /protein_id="HDX4803075.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLSWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            complement(69070..69924)
                     /gene="rpoH"
                     /locus_tag="ROH59_000553"
     CDS             complement(69070..69924)
                     /gene="rpoH"
                     /locus_tag="ROH59_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HDX4803076.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            complement(70169..71227)
                     /gene="ftsX"
                     /locus_tag="ROH59_000554"
     CDS             complement(70169..71227)
                     /gene="ftsX"
                     /locus_tag="ROH59_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HDX4803077.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYASHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            complement(71220..71888)
                     /gene="ftsE"
                     /locus_tag="ROH59_000555"
     CDS             complement(71220..71888)
                     /gene="ftsE"
                     /locus_tag="ROH59_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDX4803078.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            complement(71891..73387)
                     /gene="ftsY"
                     /locus_tag="ROH59_000556"
     CDS             complement(71891..73387)
                     /gene="ftsY"
                     /locus_tag="ROH59_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDX4803079.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQEQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETP
                     EPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQAL
                     AAEVAEEAVMVVSPAEEDQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISL
                     FRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEM
                     GEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFR
                     AAAVEQLQVWGLRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKS
                     HLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLD
                     GTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            73537..74133
                     /gene="rsmD"
                     /locus_tag="ROH59_000557"
     CDS             73537..74133
                     /gene="rsmD"
                     /locus_tag="ROH59_000557"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HDX4803080.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     EKGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD"
     gene            74123..74392
                     /locus_tag="ROH59_000558"
     CDS             74123..74392
                     /locus_tag="ROH59_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HDX4803081.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLVWQKKFKVKK"
     gene            complement(74395..74754)
                     /locus_tag="ROH59_000559"
     CDS             complement(74395..74754)
                     /locus_tag="ROH59_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HDX4803082.1"
                     /translation="MSKPPLFFIVIIGLIIVAASFRFMQQRREKADNDMAPLQQKLVV
                     VSNKREKPINDRRSRQQEVTPAGTSMRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            74895..75521
                     /locus_tag="ROH59_000560"
     CDS             74895..75521
                     /locus_tag="ROH59_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HDX4803083.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            75595..77793
                     /gene="zntA"
                     /locus_tag="ROH59_000561"
     CDS             75595..77793
                     /gene="zntA"
                     /locus_tag="ROH59_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HDX4803084.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTTVQNTNDCCCDGACSSTPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     AVQKAGYSLRDEQASDEPQESRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSVAATGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLSNGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAQSQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGVIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTELNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGVFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRK"
     gene            complement(77895..78140)
                     /gene="tusA"
                     /locus_tag="ROH59_000562"
     CDS             complement(77895..78140)
                     /gene="tusA"
                     /locus_tag="ROH59_000562"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HDX4803085.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            78350..79015
                     /locus_tag="ROH59_000563"
     CDS             78350..79015
                     /locus_tag="ROH59_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HDX4803086.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSIFGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRHWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            79088..79645
                     /gene="dcrB"
                     /locus_tag="ROH59_000564"
     CDS             79088..79645
                     /gene="dcrB"
                     /locus_tag="ROH59_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HDX4803087.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADNQQKAQTTAENIINTLVIQ"
     gene            complement(79649..80899)
                     /locus_tag="ROH59_000565"
     CDS             complement(79649..80899)
                     /locus_tag="ROH59_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312349.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803088.1"
                     /translation="MKHCCKNVVILMPEPVAEPALNGLRLNLRIVSIVMFNFASYLTI
                     GLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADLLGPKKIVVFGLC
                     GCFMSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIG
                     RVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASK
                     GKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFV
                     GTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFP
                     ALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVA
                     IALLLTWRLKKRPPVEIPEAASSS"
     gene            80998..82047
                     /locus_tag="ROH59_000566"
     CDS             80998..82047
                     /locus_tag="ROH59_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDX4803089.1"
                     /translation="METPQPDKTGMRILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERILQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGIYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            82102..82689
                     /gene="acpT"
                     /locus_tag="ROH59_000567"
     CDS             82102..82689
                     /gene="acpT"
                     /locus_tag="ROH59_000567"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HDX4803090.1"
                     /translation="MYRIVLGKVSTLSAAPLPLGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPETPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYNSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            82800..84374
                     /gene="nikA"
                     /locus_tag="ROH59_000568"
     CDS             82800..84374
                     /gene="nikA"
                     /locus_tag="ROH59_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HDX4803091.1"
                     /translation="MFSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKNELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWVLQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPRQYDP
                     QKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     PLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            84374..85318
                     /gene="nikB"
                     /locus_tag="ROH59_000569"
     CDS             84374..85318
                     /gene="nikB"
                     /locus_tag="ROH59_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HDX4803092.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLNFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            85315..86148
                     /gene="nikC"
                     /locus_tag="ROH59_000570"
     CDS             85315..86148
                     /gene="nikC"
                     /locus_tag="ROH59_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HDX4803093.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLIIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFIDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            86148..86912
                     /gene="nikD"
                     /locus_tag="ROH59_000571"
     CDS             86148..86912
                     /gene="nikD"
                     /locus_tag="ROH59_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HDX4803094.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSHGK
                     IVEQGDVETLFNAPKHAVTRSLVSAHLALYGMELAS"
     gene            86909..87715
                     /gene="nikE"
                     /locus_tag="ROH59_000572"
     CDS             86909..87715
                     /gene="nikE"
                     /locus_tag="ROH59_000572"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HDX4803095.1"
                     /translation="MTLLNVSDLSHHYAHGGFSGKHQHQAVLNNVSLALKSGETVALL
                     GRSGCGKSTLARLLVGLESPSQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKAEQLARTSEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGDKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV"
     gene            87721..88122
                     /gene="nikR"
                     /locus_tag="ROH59_000573"
     CDS             87721..88122
                     /gene="nikR"
                     /locus_tag="ROH59_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HDX4803096.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            88321..89067
                     /locus_tag="ROH59_000574"
     CDS             88321..89067
                     /locus_tag="ROH59_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDX4803097.1"
                     /translation="MKSLSKSSQIPLYQQVVEWIRESIYTGDLVEDDRIPSEYQIMDM
                     LEVSRGTVKKAVAQLVKEGVLIQVQGKGTFVKKENVAYPLGEGLLSFAESLESQKIHF
                     TTEVITSRIEPANRYVAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCPGIV
                     EIDFNQHNLFPTIESLSQRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFF
                     SRGLPVEFGNVWLKGNKYYLGTVLQRREVS"
     gene            89092..89565
                     /locus_tag="ROH59_000575"
     CDS             89092..89565
                     /locus_tag="ROH59_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX4803098.1"
                     /translation="MQGIQFQENFIQRLPAGLSVEQIIRQLAQPLVTAELVVPDFADH
                     VLEREATYPTGLPTEPPCVAIPHTDHKHVRHNAIAVGILPEPVVFADMGGDPDPVPVR
                     VIFLLALGESNKQLNALGWIMEMIQDTPFMCALLTMETTEIHTAILNKMKERGEI"
     gene            89562..89843
                     /locus_tag="ROH59_000576"
     CDS             89562..89843
                     /locus_tag="ROH59_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDX4803099.1"
                     /translation="MSQTILFVCATGIATSTAVTEKVMEYCKEHGLNVNYSQTNVASL
                     PGNTDGVALVVSTTKVPYELDVPVVNGLPIITGIGEEKVLAQIVSILKK"
     gene            89920..91278
                     /locus_tag="ROH59_000577"
     CDS             89920..91278
                     /locus_tag="ROH59_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDX4803100.1"
                     /translation="MNDIAHTLYNIVQYILGFGPTVMLPLVLFILALFFKVKPAKALR
                     SSLTVGIGFVGIYAIFDILTSNVGPAAQAMVERTGINLPVVDLGWPPLSAITWGSPIA
                     PFVIPLTILINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSSGSLFFGLLAAAIAA
                     VVVLKLADWSAPLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPE
                     TVQKKFGIFGEPMMVGTILGIFLGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEG
                     LLPLSEAIKKYLNAKYPDRDDLYIGLDIAVAVGNPAIISTALLLTPISVFIAFVLPGN
                     EVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAKDV
                     NFKFAEGSSGQVSSFLDGGNPFRFWLLEIFNGNLIAIALVPVIALVLYGIFRMTRSTV
                     YA"
     gene            91271..92779
                     /locus_tag="ROH59_000578"
     CDS             91271..92779
                     /locus_tag="ROH59_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDX4803101.1"
                     /translation="MPDNSAAIVIDIGTTNCKVTCFSCLDATTLGAHKFVTAKQISPQ
                     GDVDFDIDALWQEVRQAIAQLNAASPLPVRRISIASFGESGVFLDEHGEILTPMLAWY
                     DRRGEEYLATLSEADSAALYDICGLPLHSNYSAFKMRWLLEHYPLRNRRGLRWLHAPE
                     VLLWRLTGEQRTDITLASRTLCLDVRKGEWSAKATALLHVPCSAFAPLVQPGEHAGWV
                     SESLCKTLGFSQPVSVTLAGHDHMVGARALQMMPGDILNSTGTTEGILQLDTQPTLDE
                     QAKRDKLANGCYSLANQFTLFASLPVGGFALEWLRNTFRLTDEEIAASLNRGYADYLA
                     GNWSLDDIPVFIPHLRGSGSPYKNRHTRGLFYGLGDTLNIDMLISSVSLGLTMEFANC
                     FACFNVPGTSVLKVIGPATHNPLWLQLKADILQRPVEAIAFSEAVSVGALLTAAPDIP
                     PPQVTIAQRLLPNRARYHQLQRYQHKWKSWYQLKLQQEGVMPLHHREEHYVD"
     gene            92769..93038
                     /locus_tag="ROH59_000579"
     CDS             92769..93038
                     /locus_tag="ROH59_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDX4803102.1"
                     /translation="MLTKTVEVRNSTGLHARPAACLAKAAKKCSCKVTLHYEGNDINA
                     TSMMNIMRAGIKGGKTVEIRCDGDDENEAIQTLTALFRDRFGEAE"
     gene            93070..>93744
                     /locus_tag="ROH59_000580"
     CDS             93070..>93744
                     /locus_tag="ROH59_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase"
                     /protein_id="HDX4803103.1"
                     /translation="MPLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLP
                     NFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLHLDHGKTQEDVKQAVRAGFTSVM
                     IDGAAFSFEENIAFTQEAVDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKT
                     FVERTGCDMLAVSIGNVHGLDDIPRIDIPLLKRIAEVSPVPLVIHGGSGIAPEILRSF
                     VNYRVAK"
BASE COUNT        22441 a        25441 c        23700 g        22162 t
ORIGIN      
        1 cacgctcctg ttgaccaccg ggtcttaact ggaatttaaa tgcctgtagt cgtttcacag
       61 gtcaaattat attttggtct atgaaaaaag aaaccgatat ccggcgtgga aggcattgtg
      121 ttttcctgat gcatgttcac ctggtctttg tcgccaaata ccaacgccag atttttgacc
      181 atgacgcgac agaaaaacta cgcacttact tttcaaatgt atgtgctgat tttgaagctg
      241 aacgggttga aatggatggc gaacttatat ccccgccctg aaggacgggg ttttaccgcg
      301 caccggataa atcgcaagtt attttggtca gatacagcgt cgtatccgtt aaaagcgttg
      361 tcacttactt aagtttattt ccagcgtttc accatctacc gtcagatcgc gccacgcttt
      421 cggcctcgtc cccagttttc catccttcgc agctgtgagt aatttttctt tcgttatttt
      481 gcgcggaagt aaactcatat caagcgcgtc ccattctttt ctggctgagt caaagccata
      541 gacaatgact ctgtcatcat taaaagcaaa caggatccgc tccgcctgac catcactatt
      601 cagatcttgc tcgaccagta cgcaggcgtc tttttcaata caggtcatca cgttatagcg
      661 atcctggatt aaggccgacc agaatgtcgc atccggttta ccagaacctg gggcaattaa
      721 cacattatcg gctaatactt tttccgatac ctgttcctga agatgttgct ctccatctaa
      781 cgccatcagc agatcccgcg cgcgtttcgg gtctttcata tactcggcat cgcttttcag
      841 cgactcaagc gccgcacgtc catagcgacc gctctgttcg agcatgtaga tagttacctg
      901 gtctggcgtg tttttaccgc tctgataacg cgccatatga ctgttcacgc taatgcgcat
      961 actgtccagc accggcgaat taagaagcac cagtattacc aacaccaata acgaaaccgc
     1021 aaggttcact ttgccctgaa gatcaagggg attttgccct ttacgccaga cgatactgac
     1081 aaaatacccc agcgaccata ccagtaacac cagcaccgcc agcgcgccct gcaagcggtc
     1141 gacagtccag ccgtactgag cgacccgcag ccataacgcc caggcggcga cgaacacata
     1201 cagcggagca accagcaaag cggttttaat caggcaacgc aatggccccg tccagggaag
     1261 tgacgctttt tgcggatcgc ggacaatagc cattaagatc aattgcaaaa aggccagcgt
     1321 caacagcaac ccggcggcgg agatgtggcg agaaatcgcg ctcaggcccg taaacggcag
     1381 ggtgataata aacatcaggg ttagcaatga tactaacggc agcaaccccg tggcgattaa
     1441 cgtgaacaac ttttgaatag agtcgattaa acgtgactgt gttcgcgcga ggatcaccgc
     1501 cagcgcggta accagaccta acgtgagata aagttgcaaa aaagagcgtt ttgaaaaacg
     1561 tgatgccaac aagtttaaac aactcactcc acagtaaaag taccagccac gttaggccat
     1621 tggcgagaaa aatcaccagt aatataagta cgttatgcca tactgactgg taaaagtagc
     1681 gatagcggct actgtcattg cggatgcgaa ggctttgttg tatccacggt agcaacaaca
     1741 ttgccatcag cagcagatag cagccaaaat cccaaagcgc cttttcagct ctccaggggg
     1801 tcatgccatc agtttgccac ttcagcaagc cgctcattcc cagcgtggca ataaacacca
     1861 gcgccagcca tccccaaagg cgattctgtt taaaggagat cacggagaag agtaaaacgg
     1921 atgaaaacgc gacggtcgca ggcacgccat aaacaatcca actgagattt tttccggcaa
     1981 gccaggcgat cagcaggtag caaaccagcc cctgaagtaa tccggtagca atcatccccc
     2041 agcgtgttgc cggtgaaagt tcaacgttat ccatgttggt tatccagaat caaaaggtgg
     2101 gttaattatc gcatcgggca gtagtatttt gcttttttca gaaaataatc aaaaaaagtt
     2161 agcgtggtga atcgatactt taccgattga atttgcatca atttcattca tgaatgcggt
     2221 tccactcaca atattcccgc catataaacc aagatttaac cttttgagaa cattttccac
     2281 acctaaaatg ctatttctgc gataatagca accgtttcgt gacaggaatc acggagtttt
     2341 ttgtcaaata tgaatttctc cagatacgta aatctatgag ccttgtcgcg gttaacaccc
     2401 ccaaaaagac tttactattc aggcaataca tattggctaa ggagcagtga aatgcgcgtt
     2461 aacaatggtt tgaccccgca agaactcgag gcttatggta tcagtgacgt acatgatatc
     2521 gtttacaacc caagctacga tctgctgtat caggaagagc tggacccgag cctgaccggt
     2581 tatgagcgcg gggtgttaac taatctgggt gccgttgccg tcgataccgg gatcttcacc
     2641 ggtcgttcac cgaaagataa gtatatcgtt cgtgacgata ccactcgcga tactttctgg
     2701 tgggcagaca aaggcaaagg taagaacgac aacaaacctc tctctccgga aacctggcag
     2761 catctgaaag gcctggtgac caggcagctt tccggcaaac gtctgttcgt tgtcgacgcc
     2821 ttctgtggtg cgaacccgga tactcgtctt tccgtccgtt tcatcaccga agtggcctgg
     2881 caggcgcatt ttgtcaaaaa catgtttatt cgcccgagcg atgaagagct ggcaggtttc
     2941 aaaccagact ttatcgttat gaacggcgcg aagtgcacta acccgcagtg gaaagaacag
     3001 ggtctgaact ccgaaaactt cgtggcgttt aacctgaccg agcgcatgca gctgattggc
     3061 ggcacctggt acggcggcga aatgaagaaa gggatgttct cgatgatgaa ctacctgctg
     3121 ccgctgaaag gtatcgcttc tatgcactgc tccgccaacg ttggcgagaa aggcgatgtt
     3181 gcggtgttct tcggcctttc cggcaccggt aaaaccaccc tttccaccga cccgaaacgc
     3241 cgcctgattg gcgatgacga gcacggctgg gatgatgacg gtgtgtttaa cttcgaaggc
     3301 ggctgctacg cgaaaactat caagctgtcg aaagaagcgg aacctgaaat ctacaacgct
     3361 atccgtcgcg atgcgctgct ggaaaacgtc accgtgcgtg aagatggcac aatcgacttt
     3421 gatgatggtt caaaaaccga gaacacccgc gtttcttatc cgatctatca catcgataac
     3481 atcgttaagc cggtttccaa agcgggccac gcaactaaag ttattttcct gacagcagac
     3541 gcctttggtg tgctgccgcc ggtttctcgt ctgactgccg atcaaaccca gtaccacttc
     3601 ctctctggct tcaccgccaa actggctggt acagagcgcg gcatcaccga accgacgcca
     3661 accttctccg cttgcttcgg cgcggcgttc ctgtcgctgc acccgaccca atacgcagaa
     3721 gtgctggtga aacgtatgca ggcagcgggt gcgcaggcgt atctggttaa caccggctgg
     3781 aacggcactg gcaaacgtat ctccattaaa gatacccgcg ctattatcga cgccatcctc
     3841 aacggttcgc tggataacgc agaaaccttc actctgccga tgtttaacct ggcgatccca
     3901 accgaactgc cgggcgtaga cacgaagatc ctcgatccgc gtaacaccta cgcttctccg
     3961 gaacagtggc aggaaaaagc cgaaacgctg gcgaaactgt ttatcgacaa cttcgataaa
     4021 tacaccgaca cccctgcggg tgccgcgctg gtagcggctg gtccgaagct gtaatgattt
     4081 gaagctggag aatatctatc cagtatctta tagaaagcaa aacgggaggc accttcgcct
     4141 cccgttttat ttacccttct tttgtcgtgc cctgcgcccg cgttaccggc actggcagcc
     4201 aggcgcgaat ggaaagcccg ccccgttcgc tggtgccaag ctccagcatc ccgttatggt
     4261 tatccacgat acgctgcaca atcgccagcc ctaatcccgt gccgctaata gtgcgcgcac
     4321 tgtcgccacg aacaaacggc tggaacaggt gcttacgttg ttccggcgca atacccggac
     4381 cgtcatcttc tacctggaac caggcgcgat tcggctccgt gccgctgctg actttgatcc
     4441 agccattgcc gtaacgggcg gcgttgacca ccatattcgc taccgcgcgt ttgatcgaca
     4501 gcgggtgcat tttcacctca atgctgccgg ggtaaagcgc agtttcaatt tcccgctcat
     4561 agccactttc ggcagcaata acctcaccga gtactgcgtt gagatccgcc atttccatcg
     4621 gcatctcctg cccggtgcgc aggtagtcga taaactgctc aatgatggcg ttgcactctt
     4681 cgatatcttt attgatcgat tctgccaggt agccatcctg ctcgctcatc atctcggttg
     4741 ccaggcgaat acgcgtcagc ggcgtgcgca gatcatggct tacccccgcc atcagcagcg
     4801 tgcggtcatc cgccagttgc ttaacaccag ccgccatatg attaaaggcg cgggtaacgg
     4861 aacgcacctc cgaagcgcca tattcacgca gcggcggcgg aataatccct ttacccacct
     4921 gcaaggctgc gtgttcgaga tcgaccaacg gtcggttctg gatacgaata aacagccacg
     4981 ccccgcctat cgccaatagc ataatcgcca acgtataacg gaacagcggg gagaaatcgc
     5041 cctgatgaat ttcggttagc ggcacgcgta cccagatatt gggagacaac caggttttca
     5101 gccagacgac aggcgaactt ttgttaacct cgacgcgaac ttccgtcgga ccgcccagtt
     5161 gctgcgccat ctgatggctt aagaattcat agtgttgcgc ccaacgcagc ccggcctctt
     5221 cggcggcttc gttggaatag agagagatcc ccagctcacg gtagatctcc cgacggaaag
     5281 cgggaggcac aaccaactgc gtgccgtcct ccagttgcag tttgtcggtc atcaacatac
     5341 gcacttcgta cgcgaggact ttattaaact gctggaggct cggcaaaatc gcgaagttca
     5401 gcaccaccag ataagtcgtc accaggctga caaacagcaa ggtgacgatg agcaataacg
     5461 tacgggcaaa tgaacttcgt ggcgagaagc gcaatcgcct catgctttag aaccgtccgg
     5521 tacaaagacg tagcccagac cccagacggt ctgaatgtaa cgcggatgcg ccggatcttc
     5581 ttccaccatg cggcgcagac gcgaaatctg cacgtcgatg gagcgttcca ttgcggaata
     5641 ttcacgacca cgggcaaggt tcatcagctt atcgcgggag agcggctcac gcggatggct
     5701 gaccagtgcc ttcagtaccg caaactcacc actggtgagc ggcatcggct cgtcttcgcg
     5761 gaacatttcg cgcgtaccga ggttaagttt gaacttaccg aaagcaatta ccgcctcttc
     5821 ctgtgacggt gcgcctggca gttcgttcgc ctgacgacgc agcaccgcac gaatgcgggc
     5881 cagcagttca cgcgggttaa acggttttgg aatgtaatcg tcagcgccaa tctccaggcc
     5941 aacgatacgg tccacttctt cccctttcgc cgtcaccata atgatcggca tcgggttact
     6001 ctggctacga agacgtcggc aaatcgacaa gccatcttca ccaggtaaca tcaaatccag
     6061 taccataaga tggaaagatt cacgagtcag caggcgatcc atctgttctg cattagcgac
     6121 gcttcgaacc tggaagcctt gttcggtgag ataacgttcc agcagcgcgc gcaggcgcat
     6181 gtcgtcatca accaccagaa tcttgtagtt ctcttgcatt gtttgtactc ccaaaggttc
     6241 gcaacaattt gtaagcgtgt attcttaaaa aagctcacgt tcgtcaccag ctaaatctgg
     6301 tatgaatttc agcctaaatt gttacaaagc atattaaaca gcagcttaag tatacaattt
     6361 attcggcgaa acattattga ttctgttgat atgatcacgt tatacccaat gtgcgcatta
     6421 tcaaacagac aaagggaatc aacgagatga aaacgcccct ggttacccgg gaagggtatg
     6481 aaaaactcaa acaagagctt aattatctct ggcgtgaaga acgcccggag gtcacaaaga
     6541 aagtgacctg ggccgcaagt ctgggcgacc gcagcgaaaa tgctgactat cagtataata
     6601 aaaagcgcct gcgtgaaatc gaccgtcgcg tgcgctatct cactaaatgc atggaaaatc
     6661 tcaaaatcgt cgattactcc ccgcagcagg aaggcaaagt cttttttggt gcgtgggtgg
     6721 agattgaaaa cgacgatggt gtgactcacc gtttccgtat tgtcggctac gatgaaattt
     6781 ttggccgtaa agattacatc tctatcgatt ccccgatggc ccgcgcattg ctgaaaaaag
     6841 aagtcggcga tctggcggtg gtgaataccc ctgccgggga agcgagctgg tatgttaatg
     6901 ctatcgagta cgtgaaaccg taaggaagag tcttaacctc ctgccgatgg ctggcatttt
     6961 tgccagccag tccgtataac tatcccctga tttttgatcc gaaaagatga actcaaacca
     7021 tgatgaatga ttcgttctgc cgcattattg cgggtgaaat tcaggcgcgc ccggaacagg
     7081 ttgacgctgc cgttcgcctg cttgacgaag ggaataccgt gccgtttatc gcacgttatc
     7141 gtaaggaaat caccggcggt ctggatgaca cgcagctgcg taatctggaa acgcgtctga
     7201 gctatctgcg cgagctggaa gagagacgtc aggcgatcct caagtctatt tccgagcaag
     7261 gcaaactcac cgatgatctg gcgaatgcca tcaacgccac cctaagcaaa accgaactcg
     7321 aagacctcta cctgccctac aaacctaaac gccgcacccg tgggcaaatc gccattgaag
     7381 cagggcttga gccgttggcc gatctgctgt ggagcgatcc gtcacacacg ccagaagtcg
     7441 ccgctgcaca atatattgat gccgataaag gcgtggcaga taccaaagcc gcgctggacg
     7501 gcgcgcgcta tatcctgatg gaacggtttg ccgaagatgc cgcgctgctg gcgaaagtgc
     7561 gtgattatct gtggaagaac gcgcatctgg tctcaaccgt ggtgagcggt aaagaagagg
     7621 aaggggcaaa attccgcgac tatttcgatc atcacgaacc actgtcaacg gtgccttctc
     7681 accgcgcact ggcgatgttc cgtggtcgta acgaaggcat acttcagctt tcgctgaatg
     7741 ccgatccgca gttcgaagag ccgccgaaag agagctattg cgagcaaatc atcatggaac
     7801 accttggcct gcgcctgaac aatgccccgg cggatagctg gcgcaaaggt gtggtgagct
     7861 ggacgtggcg catcaaggtg ttgatgcatc tggaaactga actgatgggc accgtgcgcg
     7921 aacgcgcgga agatgaagca atcaacgtct ttgcccgtaa cctgcacgat ctgctgatgg
     7981 cggcccctgc cggactgcgt gcaacgatgg gcctcgatcc gggtctgcgt accggggtaa
     8041 aagtggcggt agtcgatgca actggtaaac tggtggcgac cgataccatt tatccgcata
     8101 ccgggcaggc cgcaaaagca gcgatgaccg ttgctgcgct gtgtgaaaag cataacgttg
     8161 aactggtggc gatcggcaac ggtacagctt cccgcgaaac cgaacgtttc tatctcgacg
     8221 tgcagaagca gttcccgaaa gtgaccgcgc agaaagtgat cgtcagcgaa gctggcgcgt
     8281 cggtttactc ggcttccgag ctggcagcac aggaattccc ggatctcgac gtttcgctgc
     8341 gtggcgcggt gtctatcgcc cgtcgtttgc aggatccgct ggcggagctg gtgaaaatcg
     8401 atccgaaatc tatcggcgta ggtcagtatc agcatgacgt cagccagacg cagctggcac
     8461 gcaaactgga tgcagtagta gaagactgcg taaacgccgt tggcgtcgat ctcaacaccg
     8521 cttctgttcc tctgttaacc cgcgtggcgg gcctgacgcg catgatggcg caaaacatcg
     8581 tagcctggcg cgatgagaac ggtcagttcc agaaccgtca gcaactgtta aaagtgagcc
     8641 gtctggggcc gaaagccttc gagcagtgcg cgggcttctt gcgcattaac cacggtgata
     8701 acccactgga cgcttctacc gttcacccgg aagcctatcc ggtggtggaa cgcattctgg
     8761 cagcaacaca gcaggcactg aaagatctga tgggtaacag cagcgaactg cgtaacctga
     8821 aagcgtctga ctttactgat gagaaattcg gtgtgccgac ggtaaccgac atcatcaaag
     8881 agctggaaaa accgggtcgc gatccgcgtc cggaatttaa aaccgctcag tttgccgatg
     8941 gtgtcgagac aatgaacgac ctgcaaccgg gtatgatcct cgaaggtgcg gtgaccaacg
     9001 tcaccaactt tggcgcgttt gtcgatattg gcgtgcatca ggacggcctg gttcacatct
     9061 cttcattgtc gaacaagttt gtggaagatc cgcataccgt ggtgaaagcg ggcgacattg
     9121 tgaaggtgaa agtgctggaa gtggatcttc agcgtaaacg tatcgccctg accatgcgtc
     9181 tggacgagca gcctggcgaa accaacgccc gtcgcggcgg cggtaatgaa cgcccgcaaa
     9241 acaaccgccc ggcagccaaa ccgcgtgggc gtgaagtgca gcctgccggt aacagcgcga
     9301 tgatggatgc gctggcggcg gcaatgggca aaaaacgtta aacgcccgga ctggccccta
     9361 aacctgcgcg attaggcgtt cacgccacat ctggcaacga acgccttgcc tgacataaaa
     9421 gtgccggaga atatctccgg cctttttatt ccacaagcaa acgcataata tatcccgtta
     9481 atatttatca cttcattaac aactgaaacc ttaattaaac attaaccagc cctaataatt
     9541 cgtcatgcga attatatttt cgctgcgata taagcttgag ccatatcaac attgagtcag
     9601 attattattc aaaccaacat tcacacacat tttaagtatt gctgatagaa accattctca
     9661 ttatcattgt actgttgatt atttaatctc tccttcgttg gcaaatcatc tggtctcatg
     9721 tcgctgtcaa acgccccatg aggtagttat ccagttaatg agaaacaagt aggcacctat
     9781 gcaatacact ccagatactg cgtggaaaat tactggcttt tcccgtgaaa tcagcccggc
     9841 atatcgccaa aaactgcttt ctcttggcat gttacctggc tcctctttta atgtggtgcg
     9901 cgtcgctcca ctcggcgacc ccattcatat cgaaacccgt cgtgtgagcc tggtattacg
     9961 caaaaaagat ctggccttat tagaagtgga agcggtttcc tgttaatacg gtgataacaa
    10021 caatgaaaaa attaaccatt ggcttaattg gtaatccaaa ttctggcaag acaacgttat
    10081 ttaaccagct tactggctca cgtcagcgtg taggtaactg ggctggcgtt accgtcgaac
    10141 gtaaagaagg gcaattctcc accaccgatc atcaggtcac gctggtggac ctgcccggca
    10201 cctattctct gaccaccatc tcatcgcaga cctcgctcga tgagcaaatc gcctgtcact
    10261 acattttgag tggcgacgca gacctgctga ttaacgtggt ggatgcgtct aaccttgagc
    10321 gtaacctgta cctgacgctg caactgttgg aactcggcat tccctgcatc gtggcgctga
    10381 acatgctcga cattgccgag aagcaaaata ttcgtattga aattgatgct ctgtcggcgc
    10441 gtcttggctg cccggtgatc ccgctggttt caacccgtgg tcgcggtatt gaagcgctca
    10501 agctggcgat tgatcgctat aaagctaacg agaatgtgga actggtgcat tacgctcagc
    10561 cgctgctcaa cgaagcagat tcactggcaa aagtgatgcc ttccgacatc ccgctgaaac
    10621 aacgtcgctg gctgggcctg caaatgctgg aaggcgatat ctacagccgc gcctacgccg
    10681 gtgaagcgtc gcagcatctg gatgccgccc tcgcccgtct gcgtaatgag atggacgatc
    10741 cggcgctgca cattgccgat gcgcgttacc agtgcattgc tgccatctgt gatgtggtaa
    10801 gcaacaccct gacggcagaa cccagccgtt tcaccactgc ggtagataaa atcgtgctca
    10861 accgtttcct cggtctgccg attttcctct ttgtgatgta cctgatgttc ttgctggcta
    10921 tcaacatcgg cggggcgtta cagccgctgt ttgacgtcgg ctccgtagca ctctttgtgc
    10981 atggtattca gtggattggc tacacgctcc acttcccgga ctggctgact atcttcctcg
    11041 cccaaggcct gggcggcggt attaacaccg tgctgccact ggtgccgcag atcggcatga
    11101 tgtacctgtt cctctccttc cttgaggact ccggctatat ggcgcgtgcg gcgtttgtga
    11161 tggaccgtct gatgcaggcg ctgggcttgc cggggaaatc ctttgtaccg ctgatcgttg
    11221 gtttcggttg taacgtaccg tcggtaatgg gcgcacgtac gcttgatgca ccgcgtgaac
    11281 gtctgatgac catcatgatg gcaccgttta tgtcctgcgg cgcgcgtctg gctatcttcg
    11341 cagtattcgc ggctgccttc ttcgggcaga acggtgcgct ggcggtcttc tcgctgtata
    11401 tgctgggtat cgtaatggcg gtgctgactg gcctgatgct caagtacacc atcatgcgcg
    11461 gtgaagcgac gccgtttgtc atggagctgc cggtctacca tgtaccccac gttaaaagcc
    11521 tgattatcca gacctggcag cgtctgaaag gcttcgttct gcgtgctggt aaagtgatta
    11581 tcatcgtcag cattttcctg agcgccttca acagcttctc attgagcggg aaaatcgtcg
    11641 ataacatcaa cgactcggcg ctggcttccg tcagccgggt gatcaccccg gtcttcaagc
    11701 cgattggcgt acatgaagat aactggcagg caacggttgg cctgtttaca ggtgccatgg
    11761 cgaaagaagt ggtggtgggt acgctcaaca ccctctacac cgcagaaaat attcaggacg
    11821 aagagttcaa tccggcggaa tttaacctcg gtgaagagct gttcagtgcg gtagatgaaa
    11881 cctggcagag cctgaaagac accttcagcc ttagcgtact gatgaacccc attgaagcaa
    11941 gcaaaggcga cggcgaaatg ggtaccggag cgatgggcgt gatggatcag aaattcggta
    12001 gcgcagctgc cgcatacagc tacctgattt tcgtcctgct gtatgtacca tgtatctcgg
    12061 tgatgggagc catcgcccgt gaatcaagcc gtggctggat gggcttctcc attctgtggg
    12121 ggctgaatat cgcttactcg ctggcaacat tgttctatca gatcgccagc tacagccagc
    12181 atccaaccta cagcctggta tgcattctgg cggttattct gtttaacatc gtggttatcg
    12241 gtttgctgcg tcgcgcgcgt agccgggtgg atatcgaact gctggcaacg cgcaaatcgg
    12301 taagcagttg ctgtgcggcc agtaccactg gcgattgcca ctaaggacac gacaatggct
    12361 tcgctcattc aagtgcgtga tttactggca ttacggggcc gtatggaagc ggcccagatt
    12421 agccagacac tgaacactcc gcagccaatg attaacgcca tgctgaaaca gctagaaagt
    12481 atgggaaaag cagtgcggat tcaggaagaa cctgacggct gtctttccgg cagttgtaaa
    12541 agctgcccgg aaggaaaagc ctgtctgcac gaatggtggg cgttgcgtta accttgtttc
    12601 actgcctgtt ttgaaagccc ggtatgcgtt tgcatccggg cttttttgcg tgcggctttc
    12661 catagcagcg cgacgtaagt tcctctgaaa gcgtctcgct gggatgaaaa ctcgctaatg
    12721 cacaggtgtg gagtggcgcg tagagtcgcg gcattcaaat aacaggtgaa ggaacgccat
    12781 gagcaaaaag cagagttcca ccccacacga tgcgctgttc aaactctttt tacgccaacc
    12841 ggagacggca cgcgagcatg gcgctgctgg agttaattca aaaacatatt cgtcaacgcg
    12901 atctgatagg actggtagag caaatggcct gcttattaag tagtggatac gcaaatgaca
    12961 gacaaatcaa agggctgttt aattacatac tgcaaaccgg cgacgcggta cgttttaacg
    13021 attttatcga tggtgtggcc gaacgttcac caaaacacaa ggagagttta atgactattg
    13081 cggaaagatt gcggcaggaa ggggaacaat ccaaagcctt gcatatagca aaaataatgc
    13141 ttgaatccgg agtccctctt gcagacatca tgcgctttac cggggtgtca gaagaagagt
    13201 tggctgcggc gagccagtaa agttctgtcc cgccatttcg aaagccacct acaccctctg
    13261 cttcaacgcc accagcaggt gacaaaactc gtccggatgt gaaataaacg gcgcatgggc
    13321 cgctttggcg aagatatatg attcgctgtg aggccaaagt ttatccagca tcggcaccac
    13381 tttgcgcggc accagaccgt cgagatagcc atacaatcgc aaaaacggca tgggcacgtt
    13441 ttgcagcggc tgacggagat cgaccgtttt caggatttcc agtccgccat tgagtacgtc
    13501 aacctccggc atcggtaacg ccagaacggt tttcttcaac gcccgcgcat cctggcgcgc
    13561 cgtttcagta cccatggttt gtaacgccag gaaccgctcc actgtacgct gaaaatcatc
    13621 actgagttgc tgctgaaatc ccgccagcac gtccggtttt atccccggcc actcgtcgcg
    13681 agcactaaaa caaggtgacg acgccacggt gaccagcgcc tgaacacgct cgggatgggt
    13741 taacgcaatc tggcttgcca ccagcccgcc cagactccag cctaaccaaa tggctttatc
    13801 tggtgcctgt cgcagcacga cttcggccat atcagcaagt gatagcgcac caaatccccg
    13861 gctacgcccg aagccgggca ggtcaacaag gtgcagcgta aaatgcgagc taagttcctc
    13921 gtcaatgcaa cgccacactt cggcattcag tccccatccg tgcagcagca caagatgaac
    13981 attcccctga cctttggtct gccaccagat gttattcatc cgctattgtt ctctttttac
    14041 ttacaaggat gaacatatgc taacagtacc gggattatgc tggctatgcc gaatgccgct
    14101 ggcgttaggt cattggggga tttgttctgt ctgctctcgc gccgcccgta cagataaaac
    14161 gttatgccca caatgtggat tacccgccac acactctcat cttccctgcg gtcgctgcct
    14221 gcaaaaaccg ctgccctggc aaagactgct cacggtcgcc gactatgcgc cgccattaag
    14281 tccgctcatt caccagctta agttttcccg gcgcagtgaa atcgccagcg ccctgtcacg
    14341 tctgttacta ttggaagtct tacacgctcg tcgcaccacc ggcttgcaac tgcctgatcg
    14401 catcatcagc gttccgttat ggcagcgccg tcactggcgt cggggattta atcagagcga
    14461 tttgctgtgt cagccgttat cacgctggct acactgccaa tgggatagcg aagccgtcac
    14521 acgaacacgg gccaccgcga cccagcattt tcttaacgcc cggctacgca aacacaacct
    14581 gaaaaatgcc tttcgccttg aattgcctgt gcaaggtcgc catatggtga ttgtggatga
    14641 tgtcgttacc accggaagta ccgtcgcaga gattgcgcag ttgcttttac gcaatggtgc
    14701 ggcgactgtc caggtctggt gcctttgtcg aaccttgtag agcctcgatg atgggcgtat
    14761 tataaccaac taaaatagtc aactattagg ccattactat gatccgtatt tccgatgctg
    14821 cacaagcgca ctttgccaaa ctgctggcaa accaggaaga agggacacaa atccgcgtat
    14881 ttgtgattaa ccctggcacg cctaacgctg aatgtggcgt ttcttattgt ccgccggacg
    14941 ctgtggaagc caccgacact gccctgaaat ttgacctgct gaccgcgtat gttgatgagt
    15001 taagcgctcc ttacctggaa gatgcagaga tcgattttgt taccgaccag ttgggttcgc
    15061 agctgacgct gaaagcgcct aacgccaaaa tgcgtaaagt ggctgacgat gcgccgctga
    15121 tggagcgcgt ggagtatatg ctgcaatcac agatcaaccc acagcttgct ggtcacggtg
    15181 gtcgcgtttc gctgatggaa atcaccgaag acggttacgc cattttgcaa tttggcggtg
    15241 gctgtaacgg ttgttccatg gtcgacgtca ccctgaaaga ggggatcgag aagcagttgc
    15301 tgaacgaatt cccggagctg aaaggtgtac gcgatctcac cgaacaccag cgcggcgagc
    15361 actcttacta ctaagttctc tccccttttg tcgattgccc gatgtgacgc taaagcgtct
    15421 tatcgggcct gtacgttgca cgagagtctg acgttagcgc agaattatct cagcaaatcc
    15481 aatctcttcg tttccccacg ataatatgac caacctctca taatttaaat ttaccccgct
    15541 ctggtgattc tcaagcacgt aatgttaccc gtatcattct catgggcacc aaacacactc
    15601 ataacatctg actacactaa ctcgttttag gggtcatcag ccgtggtgcc gtaacatctc
    15661 tgttcccagt tgggacaacc aggattttcc gtcagaaacc tgacgttacc cataacaaat
    15721 taaaggccag gtaaatcatg ccattagtca ttgttgctat cggtgtaatc ttgttattac
    15781 tcctgatgat ccgcttcaaa atgaacggct tcatcgctct cgtcctcgtg gcgcttgctg
    15841 ttggattaat gcaagggatg ccgctggata aagttattgg ctccatcaaa gctggtgtcg
    15901 gcggaacgct cggtagcctt gccctgatca tgggttttgg tgcgatgctg ggcaaaatgc
    15961 tggcagactg cggtggtgca caacgtatcg ctaccacgct gattgccaaa tttggtaaaa
    16021 aacacatcca gtgggcggtg gtactgaccg gttttaccgt tggttttgcc ctgttctatg
    16081 aagtgggttt cgtgctgatg ctgccgctgg tgtttaccat cgcggcttcc gcgaatattc
    16141 cactgctgta tgttggtgta ccaatggcgg ctgcactgtc tgtgacccac ggcttcctgc
    16201 caccgcatcc gggtccgact gcgattgcca ccattttcaa tgccgatatg ggtaaaactc
    16261 tgctgtacgg tactattctg gcaatcccga ccgtgattct cgccggtccg gtttacgctc
    16321 gcgtgttgaa aggtatcgat aagccgatcc cggaaggtct gtacagcgcg aaaaccttca
    16381 gcgaagaaga gatgccgagc tttggcgtca gcgtctggac ctctctggtg ccggtggttc
    16441 tgatggcgat gcgtgcgatt gccgaaatga tcctgccgaa aggtcacgct ttcctgccgg
    16501 tagcggagtt cctcggtgac ccggtaatgg ctacgctgat tgccgtgctg atcgcgatgt
    16561 tcacctttgg tctgaaccgt ggccgttcaa tggatcagat taacgacacg ctggtttctt
    16621 ccatcaaaat cattgcgatg atgctgttga ttatcggtgg tggcggtgcg ttcaagcagg
    16681 tgctggtaga cagcggcgtg gacaaataca ttgcttccat gatgcacgaa accaacattt
    16741 ctccgctgct gatggcctgg tcgattgctg ccgtactgcg tatcgcgctg ggttccgcaa
    16801 ccgtcgcggc aatcactgcg ggtggtatcg cggcaccgct gattgcaacg acgggtgtta
    16861 gcccggagct gatggttatt gcggttggtt ccggtagtgt gattttctct cacgtgaacg
    16921 atccgggctt ctggctgttc aaagagtact ttaacctgac tatcggcgag accatcaaat
    16981 cctggtcgat gctggaaacc attatctcgg tgtgcggtct ggtaggctgt ctgctgctga
    17041 atatggtgat ttgataatac tgatggccgg atgcggcgtg aacgccttat ccggcctacg
    17101 attcggcatt aattagtagg ccggtaagac gcgtcaagcg tcgcatccgg catcaaccgc
    17161 actctacttc ttcttcgctg ccgctctgcg ccgtctgtcc aaatccttca gcaacttgtt
    17221 cacaccatca tcggcaaaca tcgactcaag cgttgcggaa agtttacgtc gccagttttt
    17281 atactggtaa ctggtgccgg gaatatttac cggatctgcc atatccagcc agtcttccgg
    17341 ctggagccct aacagggcgc tgttgctatc ggcgatgtag cgctgtaagc cacgattcag
    17401 cgtcggtgtc atcgacatca acgatgcctt atgcccggca cgttttggca ggcaaccata
    17461 tttatgcaga gcatccagca gcccttgctt cgccagttcg cgatcctgat acagaccgcg
    17521 cagtaccact tcatccggat acagccccag cgttttgccc agcgttaaat ccccactctc
    17581 ccagtagccg cgtagcgtag gcaggtcgtg tgtcgccgca accgccatcg actgctctgg
    17641 gtacgctttc ggtgcgcgga atgtcttctc gtggtcgttt tcgaaataga gcactttgta
    17701 ggagtacaca ccgctgctgc gcagcttacc gacaatctct accggtacgg taccgagatc
    17761 ttcaccaatc accatacagc gatgacgttt actttcgagt gccagaatcg agagcagatc
    17821 atccaccgga tagtgaacat acgcgccctg atctgccgtc tcgccatacg gtatccacca
    17881 caaacgcagc atcgacatca cgtgatcaat tcgtaatgcg ccgcagtttt gcatattggc
    17941 acgcaacagc tcgataaacg gttcataggc acgcgcggtg atgatatgcg ggtccattgg
    18001 cggcaatccc cagttctgcc ccaacgggcc gaggatatcc ggcggcgcgc caaccgacgc
    18061 tttcaggcaa tacagttcac ggtcgcacca ggtttctgcc ccaccttctg ctacaccaac
    18121 ggccagatca cgatacaagc caatcggcat ttcatagccc tggcttatct cccagcaggc
    18181 ggcaaactgg ctgtaagcca gccactgcaa ccagagataa aaatcgacgt catcacgatg
    18241 ttcttcgcag aactggcgca cttctggcga atccacgttc tgatacatct ctggccatgc
    18301 tggccagccc cagcgcattt cgtcctcttt cacttgctgg gcatgtagcg catcaaaggc
    18361 tgcctgccag aacaggctgt cgccctgctc tgcaacaaac tggcgaaacg cggtcatctg
    18421 ctcatcatca cgttgcgcga aacctttcca cgccattcgt aatgctgtca tttttagggc
    18481 ggtaaccgtg gagtaatcaa cccagtcggc atcccgcgcc tgttgcagcg tctgttgcgt
    18541 ggtcggcaac tgccaccagg cctgagcctc ttcgctaaga tggaaatctt caactgcgtt
    18601 aacgtcgata taaatcacat tcagccaacg gcgagaagac gggctgtacg ggctggcact
    18661 ttccggattt gccagataga gcgcatgaat cgggttcaga ccaataaacg acccgccacg
    18721 ttttgccaca tccaccagca tcgctttgag atcgccaaaa tccccaatac cccagttttt
    18781 ttccgatcgc agcgtataaa gctgaacgca ggcaccccac agcttttgtt tattcagcaa
    18841 cgcctgcggt tcgtaacagc gtttcggggc gacaatcacc cggcaatgcg cgcgctggtc
    18901 gtcctgggta agcgtcagcg tgtgataacc ttccggcagc ttcgtcggta gattgaacgc
    18961 tttgcccccc gtcacatggc ctttgtactg ctttccttct tcggtggtca gcagccagct
    19021 atattcgccg ctgccctcca ccaccatcgg catttttttg ccgctggtat aaactatgac
    19081 attcgggact ggcgttaccg ccactttcgt ggcggtacgt tgatgcatcg cgtcaagcaa
    19141 acgccgtttg gtttcggcgc taatcgactg cggtttaccg tgggcattga tgtaattggg
    19201 gctaatcccc gccgccagcg cggcattatc cagacgtttg ctttccatcg aacttcctta
    19261 gcgttttgcc tgccagatac gagcctgata atcgcgaata gagcgatccg agctaaacat
    19321 accgcagcgg gcggtattga ggatcgccgc gcgagtccag gcctcctggt cgcggtacag
    19381 cacatccacc tgcttttgtg cctccacata agcggcgaaa tctgccatca ccagatacgg
    19441 atcgccgccc tgtttgccga tactgtgcag catctggtcg aaggcatgct tatcgccgtc
    19501 gctgtattta ccgctttcca gctctttcaa tactgcgtcc agcaccttat ctttcttccg
    19561 ccatttcacc gggtcgtagc ctttggccag aattgccttc acttgttcca cggtatgacc
    19621 aaaaataaag atattttctt cgccgacttt ctcagcgatt tcaacgttcg caccatccag
    19681 cgtaccgaca gtaagcgcac cattgagcgc cagtttcata ttgccggtac cggaagcttc
    19741 tttacctgca gtcgaaattt gttcggagat atccgccgcc gggatcagtt tttccgccgc
    19801 cgaaacacaa taatccggca agaacaccac cttcaacttg tcgccaacca gcggatcgtt
    19861 gttgatcacg tcagccactt tgttgatcgc aaagataata tttttcgcca ggtagtagcc
    19921 cggtgctgct ttcgcgccga agaggaagac gcgcggtacg cggtcagact gcgggttttc
    19981 acgaatttct ttgtacaacg ccagaatatg cagcagattc agatgctggc gtttgtactc
    20041 atgcagacgt ttgatctgaa tatcgaaaat cgcctgtgga ttgatctcaa taccggtacg
    20101 aactttcaca aactctgcca gacggacttt attcgcctgc ttgatctcgc gatattgctg
    20161 acggaatttc gcatcatcag cgaatttttc cagattgatc agttgatcga gatcgttagc
    20221 ccactctttt ttcagtgatt tatccaacag agccgccagt gccgggttgc actgtttgac
    20281 ccagcgacgt ggggtaatac cgttggtgac attatggaat ttgttcggcc atagctggtg
    20341 atattccggg aacagatctt tcaccaccag atccgagtgc agcgccgcaa caccgttcac
    20401 cgcgaaaccg ccaaccacac acaggttcgc catatgcact tgtttgtcgt gcaccaccgc
    20461 cagtttggcc cacacttttt catcgcccgg ccaggttttc tccactagcg ttttaaagcg
    20521 agtattaatt tcgttaataa tctgcatgtg gcgcggcagt aagcctttca ccagtttcac
    20581 atcccagcgt tccagcgctt ctggcatcag ggtatggttg gtgtaagcga aagttttgct
    20641 ggtaatggcc caggcgtcat cccagctcat ctggtgctca tcgatcagca cgcgcagcag
    20701 ttctggaatc gcgattgttg gatgggtatc gttcagctga ataacttcgt aatccgccag
    20761 ttcgtgcaat ttacgccccg ccagatgatg gcgacgcaaa atatccgcta ccgagcaggc
    20821 acactggaag tattgctgca tcaggcgcag ctttttaccg gcagtatggt tgtcgtttgg
    20881 atagagaact ttggtcagtt tttctgcgtt gatgccctgc tgttcggcac gcaggaaatc
    20941 accatcgtta aatttagtca gatcaaacgg atgcgcatgc gtcgcctgcc acagacgcag
    21001 cggctgcgcc acgccattac gatagccgac aacggggaga tcccacgctt gaccggtaat
    21061 ggtaaattcc ggctcccagc gtccgtcttt cgtcacttta ccgccaatcc ctacctgcac
    21121 atccagtgct tcgttgtggc ggaaccacgg gtagttaccg cgatgccagt catccggcgc
    21181 ttcaacctgt ttgccatcga caaaagactg gcggaacaaa ccatattgat agttcagacc
    21241 gtaacccgtc gcagactgac cgacagttgc cattgagtcg agaaagcacg ccgccagacg
    21301 tcccagacca ccgttcccca gcgccgggtc gatctcttct tccaacaggt cagtcaggtt
    21361 gatgtcataa gccttcaacg aatcctgtac atcctgatac cagccgagat tcaacagatt
    21421 gttgcccgtc aggcgaccaa tcaaaaactc cattgagatg tagttaacat gccgctgatt
    21481 cgccaccggt ttggcaaatg gctgagcacg cagcatttcg gccagtgctt cgctcactgc
    21541 cagccaccac tgacgagggg tcatttcagc cgcagaattt aagccataac gctgccactg
    21601 acgtgaaagc gcttcctgaa attgcttatc gttaaaaata ggttgtgaca taggagttcc
    21661 acttttctta gattttcaac acaacgttat cgctagtttg ccaggctcga tgttgacctt
    21721 cctcatcctg cgggggatta ggcagggagg agttgcgggg atgagcaagg aaatgtgatc
    21781 tcgaccactt aaagctagtg caatccacag gattagcagc aaatcaatgc cataccgcgc
    21841 agaaaatctg tatctaagtg caaaaaatgg ccgttgcgta ttttcaaaaa gcggaaggta
    21901 actctataaa ttaagtaaag gagtgaaaca gtttcacaag taaaatatca cgtgtgctcc
    21961 atctcattct taatagattt attaagatca tctttttaga tggcactttc atcagaaatg
    22021 aagaagaaac ccttgcttaa atgaaactga tgaacataag gaaaataccg tacaacccag
    22081 tattcacgct ggatcagcgt cgttttaggt gagttgttaa taaacatttg gaattgtgac
    22141 acagtgcaaa ttcagacaca taaaaaaacg tcatcgcttg cattagaaag gtttctggcc
    22201 gaccttataa ccattaatta cgaagcgcaa aaaaaataat atttcctcat tttccacagt
    22261 gaagtgatta actatgctga ttccgtcaaa attaagtcgc ccggttcgac tcgaccatac
    22321 cgtggttcgt gagcgcctgc tggctaaact ttccggcgcg aacaacttcc ggctggcgct
    22381 gatcacaagt cctgcgggct acggaaagac cacgctcatt tcccagtggg cggcaggcaa
    22441 aaacgatatc ggctggtact cgctggatga aggtgataac cagcaagagc gtttcgccag
    22501 ctatctcatt gccgccgtgc aacaggcaac caacggtcac tgcgcgatat gtgagacgat
    22561 ggcgcaaaaa cggcaatatg ccagcctgac gtcactcttc gcccagcttt tcattgagct
    22621 ggcggaatgg catagcccac tttatctggt catcgatgac tatcatctga tcactaatcc
    22681 tgtgatccac gagtcaatgc gcttctttat tcgccatcaa ccagaaaatc tcacccttgt
    22741 ggtgttgtca cgcaaccttc cgcaactggg cattgccaat ctgcgtgttc gtgaccagct
    22801 gctggaaatt ggcagtcagc aactggcatt tacccatcag gaagcgaaac agttttttga
    22861 ttgccgtctg tcatcgccga ttgaagctgc agaaagcagt cggatttgtg atgatgtttc
    22921 cggttgggcg acggcactgc agctaatcgc cctctccgcc cggcagaata ctcactcagc
    22981 ccataagtcg gcacgccgtc tggcgggaat caatgccagc catctttcgg attatctggt
    23041 cgatgaggtt ttagataacg tcgatctcgc aacacgccat tttctgttga aaagcgccat
    23101 tttgcgctca atgaacgatg cactcatcac ccgtgtgacc ggcgaagaaa acgggcaaat
    23161 gcgcctcgaa gagattgagc gtcaggggct gtttttacag cggatggatg ataccggcga
    23221 gtggttttgc tatcacccac tgtttggtaa cttcctgcgc cagcgctgcc agtgggaact
    23281 ggcggcggag ctgccggaaa tccaccgtgc cgccgcagaa agctggatgg cccagggatt
    23341 tcccagcgaa gcgattcatc atgcgctggc ggcaggcgat gcgctgatgc tgcgcgatat
    23401 tctgcttaat cacgcctgga gtttgttcaa ccatagcgaa ctgtcgctgc tggaagagtc
    23461 gcttaaggcc ctgccgtggg acagtttgct ggaaaatccg cagttggtgt tattgcaggc
    23521 gtggctgatg caaagccagc atcgctacgg cgaagttaac accctgctgg cccgcgctga
    23581 acatgaaatc aaggacatca gagaaggcac catgcacgca gaatttaacg ctctgcgcgc
    23641 ccaggtggcg attaacgatg gtaatccgga tgaagcggaa cggctggcaa aactggcact
    23701 ggaagagctg ccgccgggct ggttctatag ccgcattgtg gcaacctcgg tgctgggtga
    23761 agtgttgcac tgcaaaggcg aattgacccg ctcactggcg ttaatgcagc aaaccgaaca
    23821 gatggcacgc cagcacgatg tctggcacta cgctttgtgg agtttaatcc agcaaagtga
    23881 aattctgttt gcccaagggt tcctgcaaac cgcgtgggaa acgcaggaaa aagcgttcca
    23941 gctgatcaac gagcagcatc tggaacagct gccaatgcat gagtttctgg tgcgcattcg
    24001 tgcgcaactg ttatgggcct gggcacggct ggatgaagcc gaagcgtcgg cgcgcagcgg
    24061 gattgaagtc ttgtcgtctt atcagccaca gcaacagctt cagtgcctgg caatgttgat
    24121 tcaatgctcg ctggcccgtg gtgatttaga taacgcccgt agccagctga accgtctgga
    24181 aaacctgctg gggaatggca aatatcacag cgactggatc tctaacgcca acaaagtccg
    24241 ggtgatttac tggcaaatga ccagcgataa agccgccgct gccaactggt tgcgtcatac
    24301 ggctaaacca gagtttgcga acaaccactt cctgcaaggt caatggcgca acattgcccg
    24361 tgcacaaatc ttgctgggcg agtttgaatc tgcggaaatt gtcctcgaag aactcaatga
    24421 aaatgcccgc agtctgcggt tgatgagcga tctcaaccgt aacctgttgc tgcttaatca
    24481 actgtactgg caggccggac gtaaaagtga cgctcagcgt gtgttgctgg acgcattaaa
    24541 actggcgaat cgtaccggat ttatcagtca ttttgtcatc gaaggcgaag cgatggcgca
    24601 acaactgcgc cagcttattc aactcaatac gctgccggag ctggaacagc atcgcgcaca
    24661 gcgtattctg cgagaaatca atcaacatca tcggcataaa ttcgcccatt tcgatgagaa
    24721 tttcgttgaa cgtctgctaa atcatccgga agtgccagag ctgatccgca ccagcccgtt
    24781 gacccaacgt gaatggcagg tcctggggct gatttactcc ggttacagca atgagcaaat
    24841 tgcaggcgag ctggaagtgg cggcaaccac catcaaaacg catatccgta atctgtacca
    24901 aaaactcggt gtcgcccacc gtcaggccgc ggtacaacac gcgcagaaac tgctgaagat
    24961 gatgggatat ggggtgtgag tttagccgga taatgcgtcg gatccggctt acatctttac
    25021 atcattcaat gctaacccgc gttacgccat ctgtttctat caaaccaaac cgcaccggca
    25081 agaaacgctc caccacggcg atattggtca gcagatgaca tgagggatgg gcgaccgtaa
    25141 attctcccgc gcccgccagc gccatcggta gcaccagttg gtcggcgaga tattccccca
    25201 ccgccgccgg gcttgccagg tagcgtttca cctctttcac caactgtgcc gcgaccacct
    25261 cggcactgac gcgcttttca ccgacgacaa aaaagcgttc ggtgatattt tcactttcga
    25321 cttcaagcga gacggtatta cccggcccct ggtcgcgcgg caggttatga atattctgtt
    25381 catgcaagga aaaactaccc gccagtgtag cgatttcacg ctcagcaaca tggcgcggta
    25441 actttcgcga actttctgcc agcgtcacgc ggatggccac ctttgccact agcggacgca
    25501 tcacactgga tacagtggaa gatgagatca accgtctgcg ctataactgg caggagagtc
    25561 gcccctccac gcttacggcg ttgctgggcg cagaggcaga aaacatcgat ctcttcgacc
    25621 gtatgcaact ggaacacgtt atcgctatct gccgccaggc aaagtcgctt tctgctgccg
    25681 gacgtgaact gtttgacatt tcgcgccagg gtaaagccag cgtcaatgac gcggatcggc
    25741 tacgcaaata cctggcgcgt tttggtctga catgggaagc aatgcaggat cagcacagct
    25801 ccagttgaat atgatggtcc ttcagcacct gcatcacgct cgcaggcggc atcgtgtcgg
    25861 tgtagacagc atcgaccatg ctgatgctac ccatattgac cattgcgtta cggccaaatt
    25921 ttgagtggtc gacaaccagc ataacgtggc gcgagttctc aatgatggcg cgtttggtgc
    25981 gaacttcgtg gtaatcgaac tccagtagcg agccgtcgct atcgatgccg cttatcccca
    26041 gaatgccgaa atcaaggcgg aactgggaga taaaatcgag cgttgcttcg ccaatgatcc
    26101 cgccatcgcg gctgcgtaat tcgccaccgg caagaatgat acggaaatcc tcttttacca
    26161 tcagcgtgtt agcgacgttg agattgttgg tcacaatgcg taaattgctg tgattaagca
    26221 gcgcgtgcgc caccgcttcc ggcgtggtgc cgatatcgat aaacagcgtc gagccattgg
    26281 gaatttgctc cgccactttg cgggcgatgc gctctttttc ttcggtctgg gtggccttgc
    26341 gatcgtgcca cggcgtgtta accgaactgg aaggcagcgc cgcaccgcca tgatggcgca
    26401 ggatcaggtt ttgctctgcc agctcgttga gatcgcggcg aatagtctgc gggctaacgg
    26461 agaaatgctc taccagctct tcggtgctga cataaccctg ctgtttaacc agttcgataa
    26521 taccgttgtg acgttgtgtt tgtttcattg ataaatccct ggaattattt tcgttttcgc
    26581 gcattgagcg aatcaacaaa agccatcgct aaacccacgg ctaacccggc gatatgtgct
    26641 ccgttcgcca tcgacatccc aaacaaatca aaccatccgg cgacaatcca gatcaacgca
    26701 aagataatta acccacgttg caggtaaatg ccactttgcg gatcgcgttc gccacgtagc
    26761 cagacgtagc ccatcagcgc atacaccacg ccagaaagcc cgccaaacca cggcccgctg
    26821 aatttttgct gcacatagcc gcttaacagg gcgctaatga gagtaatgac aattagctta
    26881 ccgctaccga ggcgtttttc caccgcaccg ccgagatacc accaccagag caggttaaag
    26941 aggatatgca tcagcgagaa gtgcattaac gcgtgggtga agtaacgcca gaactcaaat
    27001 ttcagcgtcg gatcgaatgg ccaggccagc cataacatca cttcctgatc gccgagaatt
    27061 tgcatggcga taaacaccac cacgcaggcg atcatcatca cccaggttac cggacctgcg
    27121 cgttcacgca aggcggcaaa gaaaggataa cggcgataat gcaggccact gtcggtatga
    27181 ccggactgcc aactggcggc gagataacgt ggatctgccg ggttttcgag aaaacgagcc
    27241 agctccgccc gcacgcgttc ggcctgggac tcatccgcca gccagacatc gctttggtta
    27301 tgttgttgaa tcgtgaggat aacaccctgt gtcgccatgt aatcaacaaa cgcctgcgcc
    27361 actcgggggt tagcaaaaga ggtaatcatc aacatcgttg ctgtcgctta ttccacacaa
    27421 aaggggacag tataaagcgt tacgcgccgt acgccacctc tgcgggaaac tggcgctgcc
    27481 aggcttcaaa accgccatca atgctgtaga ccacatcgta gccctgttgc agcagatact
    27541 gcgccgcgcc tttgctgcta ttgccgtgat aacacatcac catcaccggt gtgtcaaagt
    27601 cgttatcacg cataaacgcg cccagtgtgt cgttagttaa atggaaagcc tgggtcgcat
    27661 gccccattgc gaaactctgt ggatcgcgaa tatcgaccag caccgcctct ttttcctgca
    27721 acttctggtg cgcgtcggca acgttaatac attcgaactg atccatgcgt ctctctttct
    27781 ttacaaacaa gtgggcaaat ttaccgcaca gtttacgtcg aagcggcaga taaacgccat
    27841 aatgttatac atatcactct aaaatgtttt ttcaatgtta cccaaagcgc gattctttgc
    27901 taatatgttc gataacgaac atttatgaac tttaacgaaa gtgaatgagg gcagcatgga
    27961 aaccaaagat ctgattgtga taggtggcgg catcaatggt gctggtatcg cggcagacgc
    28021 cgctggacgc ggtttatccg tgctgatgct ggaggcgcag gatctcgctt gcgcgacctc
    28081 ttccgccagt tcaaaactca ttcacggtgg cctgcgctac cttgagcact atgaattccg
    28141 actggtcagc gaggcgctgg ctgaacgtga agtgctactg aaaatggccc cgcatatcgc
    28201 cttcccgatg cgttttcgcc tgccgcatcg tccgcatcta cgcccggcgt ggatgattcg
    28261 cattggtctg tttatgtacg atcatctggg caagcgcacc agcctgccgg gatcaaccgg
    28321 tttgcgtttt ggcgcaaact cagtgttaaa accggaaatt aagcgcggat tcgaatattc
    28381 tgactgttgg gtagacgacg cccgtctggt actcgccaac gcccagatgg tggtacgtaa
    28441 aggcggtgaa gtgcttactc gtactcgtgc cacgtctgct cgccgcgaaa acggcctgtg
    28501 gattgtggaa gcggaagata tcgataccgg caaaaaatat acatggcagg cgcgcggcct
    28561 ggttaatgct accggcccgt gggtgaaaca atttttcgac gacgggatgc atctgccttc
    28621 gccttatggc attcgcctga tcaaaggcag ccatattgtg gtgccgcgtg tgcataccca
    28681 gaagcaagcc tacattctgc aaaacgaaga taaacgtatt gtcttcgtga tcccgtggat
    28741 ggacgagttt tccatcatcg gcaccaccga tgtggaatac aaaggcgatc caaaagcagt
    28801 gaagattgaa gagagtgaaa tcaattacct gttgaaagtg tataacacgc actttaaaaa
    28861 gcagttaagc cgggacgata tcgtctggac ctactccggc gtgcgtccgc tatgtgatga
    28921 tgagtccgac tcgccgcagg ccattacccg tgattacacc cttgatatcc atgatgaaaa
    28981 cggcaaagcc ccgctgctgt cggtattcgg cggtaagctg accacctacc gcaaactggc
    29041 ggagcacgcg ctggaaaaac tgacgccata ttatcagggc attggtccgg cgtggacgaa
    29101 agagagcgtg ctgccgggtg gtgccattga aggtgaccgt gacgattacg ccgcccgcct
    29161 gcgccgccgt tacccgttcc tgaccgaatc gctggcacgt cactacgcgc gcacttacgg
    29221 cagcaacagc gaactgttgc tcggcaatgc aggggcgata agcgacctcg gtgaagattt
    29281 cggtcatgag ttctacgaag cggagctgaa atatctggtc gaccacgaat gggtccgccg
    29341 cgccgacgat gccctgtggc gtcgcacgaa acaaggcatg tggctaaatg cggatcaaca
    29401 atctcgtgtg agtcagtggc tgatggaata tacgcagcag aggttgtcgc tggcgtcgta
    29461 aggatgatgc ccggttgcga agtgcaaccg ggctatttga attccttaga ctattcattg
    29521 taaataattg aataacggcc ccagagctaa aatcgccaaa cttaagcacg ttacccaatc
    29581 gccccacttc ttcctatggc ttctattttt gctacgccac tggcaataat atcccaacgc
    29641 aaaaccaagc tgggcactaa tcgggccgac aaaatcagtc cacggctgcg gccaaaaagg
    29701 ggaaaaattc aggggaagcc agacaaatgt cagaaagaaa tttcggatat tttccagcaa
    29761 cgctgatttc tctggagaaa tataaagaat gaaattcgag agaattaacc agaaatagac
    29821 cggagaaaaa accagccagc aatgtagcct gttttttaat tcaggaggcg ttctgcggga
    29881 gaattgccaa ccgatgccac ccattacact gaaaaaaagt gcatattcaa ccaataactc
    29941 aagttgtaat tcctgaagag aaatacgcac aaccaggagc ggaaaggaga atattatttc
    30001 agccagaaaa gttaacgtga atataagtac ggctaaggca ataaccgtcg gccataccaa
    30061 taatggtacg ataacaaaac cgaaaattac agggtaaata taaagtctga ttttattcat
    30121 ctttaatgtc ctgatgattc ggatgatgcg tcatacatgg cacataaaca ctcatcaatc
    30181 atccactcgt cttcccaggc ctgatactgt gtgccctgtt cggactgctt aagcggattc
    30241 tcaatcgcct gccgcgcgcg ttctttcagg atggattgat tattactagc ccaagtatta
    30301 gtttgagtgg taatggcttt atcgatatcg tcctgattat ctctgatata accgtcacga
    30361 tacgtattca ataaacaggc aagagacgct gccgaccaaa atccgggaac tgaaataatg
    30421 gcatcaagca atggcgaaag agcgatatcg gcacggaaaa acatttccag cttgtactgt
    30481 aattcgacag cctcatcccc ggatacccaa tcagtcatat actggcaagc aaattgctgc
    30541 aatatttccc gttcatcctc acgccagttt tctttactgg caaggttgat acgccgtaga
    30601 gaaaatactt cgtgaatatt gtcaaattgc ccctgcgcaa caaactccag taaacaaggc
    30661 agaaaataac gaacctcatc gctgttttgc ggatcaggtc ctggactact attccaggca
    30721 ttgattaagg aataaggaat cgctcgcaac gatgtattcc gtaatgcttt ttgttcctgt
    30781 tgactcagac aatattcaca acaaaccaca aattgctgcg gcgccggata acgacgaaaa
    30841 atatgatata tctgctcaat taatgcctgc atggcaggag tggggtgcat aattaccccc
    30901 tcgcccgctg atcgtgcata aacggctgat agataaaaag ggcattcgcc gcgttcagga
    30961 aaatattaat gatatccata ttgtaatcct gcttaatgca acgttttatc catcggcaca
    31021 tagcccacat cttccaccaa actctgcccc tgcggcgtta aaaaccactc caccaatttt
    31081 tgtgtctctg acgtcgtatt ttcccgcgtt accattaagg catcgacgat atagggatat
    31141 ttgtcgttgc gaatattttc cgcagtcggt gcaataccgt taatcgctag cagttttata
    31201 tttttatcgg cattcatttg tgttgcgtaa tagcggaagg tgtagcctat tgcgtttttt
    31261 gtattacggt attcggcaac aacgttaatc attccctcca tcacgcttgc cacttccgtt
    31321 tcctgcggcg agatcatgcg gacatttttc atgacctgcg atagcatcac cgtctggctg
    31381 ccagagtctt ccgggcgttg ccaggtctgg atctcctgat cgtcaccgcc aaccgcgcgc
    31441 cagttggtaa ttgcgccact gaaaatgtca cgcacctgtt gttcagtcag ggaattaacc
    31501 ggattatccg cattgacgat gaaaacaaac gcttcacggg caaatggcgt gtacagcaaa
    31561 gtgacgcccg atttctcagc gcgttttttt tgcccatcgg aaggttgcgc cacgaaaata
    31621 atatcggcat caccgttaac gattttgtta tatgcttctt gcgtacgaga gttatccaga
    31681 taatcccaaa cgtgaaaatc ctctggtatt acacttaatg cataaaatgc agaggcataa
    31741 atggggtacg ccgccgtagc gccatcgagt cgcggccagt tttgcgtaaa ttgaatttgt
    31801 ggtttaccac gcagtggcgt cagttgatta ttaagtttat cgggtcgcca ggcccaggta
    31861 tcaatatttt cacgcacacc gacaccggga ttaagctgtt tatataaata agcctgatac
    31921 ccagcgacaa aaccaagtaa gagaagtaga aacaggagta agttacggca acgtagcccg
    31981 gacgtgccgg ttaaaggatg ccttgtcggc cagccgtatc ccagcgaaaa actgatatgc
    32041 gcgccaacgg gtataatgac tatccaccag tagtcgccac tgattaatga gagtaacaaa
    32101 acaccctgcc aggaaagcat aaggtttgcc aaccagcccg atcccatctg gcgaaattga
    32161 taatctgcca gatgtagcgc gattatccag ccaaccaggg ttaatagcgc gggtaagaga
    32221 aaaaagcatt gtcgccaggc ggctatttct cttttttctg gtgcgctatc accagcccac
    32281 acgcgaccag agaaaaatat gattatcgcc cccagcgtca gcataaagac gttgagtaga
    32341 agataaattg ttggcgtaaa gagtaaattg caaacctcaa gaatagcggc aagcccggcc
    32401 cccagcatgg caacaaccgc tgccaaaaat tgcgccagta tggggatgcc aaaaaaagtc
    32461 attaccagcg aggtcaaaat ccattttccg ctttgcatta ttctttccat tcttgctgaa
    32521 tggcgaaatt atactccccg ataaccctcg ccccctctgg acacttttcc taaataaagg
    32581 cgaaaaaaac gggacctttt ggccccgttc tgttttttag cgaacttata atctcaccgg
    32641 atcaatatgc caaatataat cggcatactc tttgatcgta cggtcagaag agaagtaacc
    32701 catattggca atgttcagca tcgcttttgc ggtccactct tcctgacgct cgtagagttc
    32761 gtcaacttta tcctgacaat cgacatagct gcgataatcc gccagtacct ggtagtgatc
    32821 gccgaagttg atcagcgaat cgaccagatc gcgatagcga cccggatctt ccggactgaa
    32881 tacaccgctg ccgatttgcg tcagcacctg atgcagctcc tcatctttct cgtagtattc
    32941 acgcggtttg tagccctgac ggcgcaattc ttccacttct tccgctgtgt taccaaagat
    33001 aaagatattg tcagcaccga catgatccag catctcgaca ttcgcaccgt ccagcgtacc
    33061 gatagtcagc gcgccgttaa gcgcaaactt catgttactg gtgccggaag cttccgtccc
    33121 cgccagcgaa atctgttcag acagatcggc cgccggaatg atcaactgcg ccaggctaac
    33181 actgtagttc gggatgaaca cgactttcag cttgtcgcca atctgcggat cgttgttgat
    33241 cactttcgct acgtcattga tcaaatgaat aatgtgcttc gccatgtaat aggccgaagc
    33301 cgccttaccg ccaaaaatat tcacgcgcgg tacccacttc gcatccgggt cggccttgat
    33361 gcggttatag cgggtgatca cgtgcaacac attcatcaat tgacgtttgt attcgtgaat
    33421 acgtttgatt tgcacatcga acagcgcttt cggatttacc accacattca gctgctgggc
    33481 gatatactcc gccagacgct ttttgttctc cagcttcgcc tgatgcaccg cgtgattaac
    33541 cattgggaaa tcacagtgtt gttgcagatc attaagcagg ctaaggtcgg tgcgccagtt
    33601 gcggcccagg tgttcgtcca acacggctga aagcgatggg ttcgctaccg ccagccagcg
    33661 acgcggcgtc acaccgttgg tgacgttggt gaaacgaccc gggaagattt tcgcaaagtc
    33721 ggcaaatagc gattgcacca tcaggttaga gtgcagttcc gatacaccgt taactttgtg
    33781 gctcaccaca accgccagcc aggccatacg cacacgacga ccattggatt catcaatgat
    33841 cgacgcccgt cccagcagat cggtatcgtt cggatactgt tcctgcaagg ttttcaggaa
    33901 atagtcgttg atttcaaaga tgatctgcag gtgacgcggc agaattttac ccagcatatc
    33961 gactggccag gtttccagcg cctcgctcat tagcgtgtgg ttggtgtagg agaagacctg
    34021 acaacacact tcaaacgcgt cgtcccagct aaattggtgc tcatcgatca gcagacgcat
    34081 catctcagga atcgacagca ccggatgggt atcgttgagg tgaatcgcaa ttttatccgc
    34141 caggttatcg taggttttat gcaactgata atggcggctt aaaatgtcct gaatggtcga
    34201 ggaaaccagg aagtattcct gacgcagtcg cagctcacgc ccggagtagg tggagtcgtc
    34261 cggatacagt acgcgagata cgttctcgga gtggttttta tcttccactg ccgcgaagta
    34321 gtcgccctgg ttgaatttac cgaggttaat ttcactactg gcttgggcac tccacaaacg
    34381 caacgtgttg gtcgcgtcgg tgtcgtaacc tgggattatc tgatcgtaag ctactcccag
    34441 aatctcttcg gtttcaatcc agcgcgtttt tttaccttcc tgctgaatgc gaccaccaaa
    34501 acggacttta tagcgcgtgt tgtggcgttt gaattcccac gggttaccgt attccagcca
    34561 gtagtcaggc gactctttct ggctaccgtt aacgatgttc tgcttgaaca taccgtagtc
    34621 atagcggatg ccgtaaccgc gccccggcaa ccctaacgtc gccagagaat cgaggaagca
    34681 agccgccaga cggcccaggc caccgttacc gaggcccggg tcattttctt catcaatcag
    34741 ctcttcgaga tttaatccca tcgcttccag tgcgccctgt acatcttcgt aaattcctag
    34801 cgacaacatg gcgttggaga gcgtacggcc aatcaaaaac tccatcgaca ggtagtaaac
    34861 ctgacgagtt tcttgcgaca actgggcacg gtttgaacgt aaccagcgct ccacgagacg
    34921 atcgcgcaca gcaaataacg ttgcgttcag ccattcatgt ttattggcga cgaccggatc
    34981 ctttccaatc gtaaacatca gcttgtaagc gatagagtgc ttaagagctt ctacgctaag
    35041 cgtgggcgat gaatatgtaa acggagcatt catataggcg tttcctgaaa actatttcaa
    35101 gcgatagtaa agctcacggt acgacttcgc cgcgacctgc cagctaaaat ccattgccat
    35161 agcctgacgt tgcacaaacc gccacagtga aggacgggac cacagtacga aagcacgtcg
    35221 aatagcccgt aacagcgacc aggcattact atcttcaaag acaaacccac tggcgacgcc
    35281 atctgcaagg ttctcaagag aacagtcaga aaccgtatca gcaagcccac cggtgcgccg
    35341 cactaacggc agcgtaccgt acttcaatcc ataaagttgc gttaagccgc acggttcaaa
    35401 acggctgggc accagaatga cgtccgcgcc gcccataatg cgatgcgaaa atgcttcgtg
    35461 atagccaatc tgaacgccca cctggccggg gtattccgct gccgccgcaa ggaaaccttc
    35521 ctgcagcacc ggatcgcccg cgccgagtag cgccagctgc ccgccctgct ccagaagacc
    35581 aggtaaggct tccagcacca ggtcgagacc tttctggctg gtcagacggc tcaccactgc
    35641 aaaaagcggc actttatcgt caaccttaag ccccattgcg atttgtaact ggcgcttatt
    35701 ttccgcttta tcttccaacg tatcgcgggt gtaacgcgag gccaacagta agtccgtctc
    35761 tggactccag attttctcgt ccacgccgtt cagtacgccg gaaagacgcc cttcacggtg
    35821 acgctgttgc aacagacctt ccataccgta ggcaaactgc ggttcggtga tctcgcgagc
    35881 gtaggttggg ctgactgccg taatgtgatc ggcatagtac agaccggcct tcaggaaaga
    35941 gatttgtccg ttgaattcca gcccatgaat attaaagaat gaccatggca attggatgtc
    36001 attcatgtga tgtgcataaa acatgccttg ataggccagg ttgtgcacag taaacaccga
    36061 cttcgccgga cgcccgcgcg ccgccagata cgcaggcgca aggcctgcat gccagtcgtg
    36121 cgcatgcacc acatcaggac gccagaatgg gtcaagcccg ctggccattt ctgccccaac
    36181 ccaccccagc agcgcaaaac gcaatacgtt gtcggtatag gcaaataagt tggtatcgtg
    36241 atacgggctt cccggacgat catagagatg cggcgcgtca atcaggtata tgccaacccc
    36301 gttgtaatga ccgaacaaca gcgtgatatg tccggcgaag gtatcacgac gggatactac
    36361 ctgcgcatcg gtcacgccac ggcgaatatc gggaaatgca ggcaacagta cgcgagcgtc
    36421 aacgccgtct gcgatttgtg ctgcgggtaa tgccccaata acatcagcca gaccgccggt
    36481 tttaagcagc gggaacatct ctgaacatac atgtaaaacc tgcattatcg ctcctgttta
    36541 tgccctaact tccgtagcat ttcgcgcgtt accagcacga tgccttcttc tgaacgatag
    36601 aaacgacgtg catcttcctc tgcgttttca ccaatcacca tgccttccgg aataacacaa
    36661 gcacgatcga tgacgcagcg acgcagacgg cacgagcgac ctacccatac ttccggtaac
    36721 aatacggcgg aatcaatgtt gcagaatgaa ttcacgcgaa cgcgcgagaa cagaacggac
    36781 tgcaccacca ccgaaccgga gatcacacaa ccgccggata ccagtgagtt aagggtcatc
    36841 ccgtggctac cggagcgatc ctgcacgaat ttcgctggcg gtaatgattc attgtaggtg
    36901 cgaattggcc aattgcgatc gtacatatcc agttccggca ccacagaggc cagatcgagg
    36961 ttcgctttcc agtaagcttc cagcgtaccc acatcgcgcc agtacggctc ggcatccggg
    37021 tcggattgta cgcaagagag cgggaacggg tgcgcatagg ccagaccggc ttcggtgatc
    37081 ttgggaatca aatctttgcc aaagtcgtgg ctggagttct catcgcgatc gtcttcttcc
    37141 agcagttcat acagatagtc ggcgtcaaag acgtagatac ccatactcgc cagagatttg
    37201 cctggatcgt tcggcattga cggcgggtta gctggttttt caacgaattc gataatttta
    37261 tcgttctcat caaccgccat aacgccaaac gcggaggctt cttcaatcgg tactggcata
    37321 caagcaacgg tgcaacgtgc gcctttttcg acgtggtcga taagcatacg cgagtagtct
    37381 tgcttgtaga tatggtcgcc cgccaggatc accacgtatt ccgctttata acggcggata
    37441 atgtcgaggt tttgggtgac cgcatctgcg gtgccgcgat accagttttc ccctttcatt
    37501 ctctgctgtg ctggcagcag atcgacaaac tcgttcattt cttcattgaa gaatgaccag
    37561 ccgcgctgga tgtgctgcac cagagtgtgg gactggtact gggtgatcac gcccatacga
    37621 cggatcccgg agttgatgca gttagacagc gcaaagtcga taatgcggaa cttaccgccg
    37681 aagtgtacgg ccggttttgc tcgcttattg gttaaatcct tcaggcgggt accacgtcct
    37741 cccgccagta tcagggcaac agatttcaat ggcagctggc gtgccaacat taagtgatcg
    37801 ttcttctcta aactaaccat gactaactcc ttttttatca tctctggaac acacacaatc
    37861 cgtgtgcagg tccctgccag acagccgtaa tcactgggtt atcctctcca gcgaatgggg
    37921 gaatggcgtg ccactcccca gcaggtaaaa caatctctgt tacctcaagc gtggcgttaa
    37981 ttgcgatcaa aaagcgatcc gagagcagaa tttgcagctg tttcggcccg ttttgccact
    38041 catccgtgct taaaggttga gcatatcgat ttagccaacg gacattgccg tcgccttctt
    38101 cccaccagcg attctccatc aaagcgggaa tgcgcttgcg cagatggatt aacgcggcgg
    38161 taaatgcggt taaaccactg cttgcctgcg accagtccaa ccaggttaat tggttatcct
    38221 gacagtaggc attgttattg ccatgctggc tgtgaccatg ttcgtcaccg gccagtaaca
    38281 tcggcgtacc ctgggagagc aacaacgttg ttaacagggc gtgaatgctg tcgcgccgcc
    38341 gttcaaccag atcaagagta ccgcctaacc cttctttacc atgattgtta ctgtaattgt
    38401 tgttggtccc gtcgcgattt tcttctccgt ttgcttcatt gtgtttatgg ttgaagcaaa
    38461 cgcagtcgcg aagcgtaaaa ccgtcatgcg cggtgacgag attaatcgcg gcactcggca
    38521 gacgatcatt acgtttaaaa acatcgctgg aggcagcaaa acgcccggca aacgccccca
    38581 gaggcaaatc ataatgcagc cagaaacgac gggctgcatc gcggaaatga tcgttccact
    38641 cggcaaacag cggcgggaaa tttcccacct gataaccacc aggagcgata tcccacggtt
    38701 cagcaattaa cttcacctgc gagagcaccg ggcagttctg gatagcggta aacaacggcg
    38761 catcctgacg aaactctggc gtacggccca tgactgccgc cagatcaaag cggaaaccat
    38821 cgacgtggca ggtttctacc caataacgca ggcaggcgct ggcataatct accaccgccg
    38881 gatgactcaa attgagcgtg ttgccacaac cggtccagtt gtgataatcg ccgtcttctc
    38941 ttatccaata atagctacgg ttgtcgatcc cacgcagcga gaataacggg ccgtcgaggt
    39001 ccagttccgc actatggttg agcacgatat caagaatgac ttcgataccc gctttatgca
    39061 gtgctttgat tgcatcgcga aactcatcca gcgccgtttc tggcgagcag gcatacgccg
    39121 gatgcagcgc aaacatcgcc accgggttgt aaccccagta gttactaagc cccatacgtt
    39181 gcagacgtgg ttcactggca aattgtgcca ccggcagcag ttccagcgcg gtaatgccca
    39241 actgtttcaa atagttgatc atcaccggat gccccagggc tttataagtg ccacggatct
    39301 cgaccgggat ctccgggtgc aggtacgtta atcctttgac atgggcttca taaatgatgg
    39361 tgctgcccca cggcgtgcgc ggcggggcat catcttccca gtcatagtga tcaatcacca
    39421 ctacgcattt cggcgcaatg gcggcgttgt cgcgatagtc aggttcatta tgaccggcgt
    39481 gcagcagcgg gttatcttta aactccccgt caatttgccg cgcgcaagga tcaatcaaca
    39541 acttcgccgg gttaaagcga tgcccctcgg caggttgcca ggggccatga actcgataac
    39601 cataacgcaa acccgggcgc gcatccggca gataaccgtg ccaaatgtcg ccactgtgcc
    39661 ctggcaagtc atagcgatgt tcctggccat tggcatcaaa gacacacagc tctacccgct
    39721 cggcatgagc ggagaaaagt gtgaagttga cgccctgacc gtcgtaatgc gcgccgaggg
    39781 gagtgggttt gccaatggcg agttgtgtca ttctgcctcc cgaaccagcc agatagtggc
    39841 cagaggtggt agcgtcaggc tcagtgaatg ttgacgaccg tggctggcaa tctcatcgct
    39901 gtgtactgcg ccgccattgc ctgcattact gccgtgatag tgcatggaat cggtattgag
    39961 gatttcacgc catttacccg gctggttaat accgaagcga taatcatgac gcggcaccgg
    40021 tgtaaagtta ctggcaacga tgatttcgtt accctcttta tcgcgacgca caaagatcag
    40081 caccgagcgt tctttgtcat ccaccaccag ccattcaaag ccgtacgggt caaaatccag
    40141 ttcatgcatt gctttatggt ggcggtaggt gtggttcaga tcgcgcacca gacgctggac
    40201 accgtggtgc cagttatcgc cgccttccaa cagatgccag tcgaggctgg cgtcatggtt
    40261 ccactcgcgg ccctgggcaa attcgttccc catgaacagt agtttcttgc ccgggaatgc
    40321 ccacatccag ccgtagtagg cgcgcaggtt agcgaatttc tgccatgcgt cgcccggcat
    40381 ccggtcgaga atcgattttt taccgtggac cacttcatca tgcgacaacg gcaggacgaa
    40441 gttttcagtg tagttgtaga gcatcccgaa ggtcagttta tcgtgatgat actgacgata
    40501 aatcgggtcg agcttcatgt agtccagggt gtcatgcatc cagccgaggt tccacttgta
    40561 ccagaagccc agaccgccca tatcctgtgg acgagaaacg ccagggaaat cggtagactc
    40621 ctccgccatt gtcactgcac cggaaacctg ctcaccaaga atacggttgg tattacgcaa
    40681 gaattcaatc gcttcaagat tctcgcgacc gccaaattcg ttcgggatcc actccccctc
    40741 tttacggctg tagtcgcgat aaatcattga cgccaccgca tcgacgcgca gcgcatcaat
    40801 accaaaacgt tcaatccagt aaagcgcgtt accgacaagg aagttactga cttcacggcg
    40861 accatagttg tagatcagcg tgttccagtc ctgatgatag ccttcgcgcg gatcgctgtg
    40921 ttcatacaag ttcgtgccat caaattcggc aagcgcaaag tcatcggtcg ggaagtggcc
    40981 tggcacccag tcgagaatca cgttcagacc agctgcgtgt gcggcatcaa tgaaataacg
    41041 gaagtcgtcg cgagtaccaa aacggcgggt cggtgcatac aggccggttg gctgataacc
    41101 ccaactgcca tcgaagggat gctcgttaat gggcagtagc tcgagatggg taaagcccat
    41161 ccatttagca taaggcacca gttgatcggc cagctcgcgg tagctcaacc agaaattgtt
    41221 gtcggtgtgg cgacgccagg agcccaggtg aacttcataa atagagattg gcgcatcaaa
    41281 ctgattcgct tttttgcgct cttcagtctg cacaaccttt tccggcagcc cgcaaataag
    41341 agacgcggtt tccgggcgca tttgcgcttc gaaggcataa gggtcggact tcagacgcaa
    41401 gttgccattg gcatcaatca tctcgtattt atagagctga ccgttatgcg ccccagggat
    41461 aaacagttcc cagattccgc tctctttacg caggcgcatc ggatgacggc gaccgtccca
    41521 gtagttgaat tgcccaacca ccgagacccg acgggcgttt ggagcccaga cagaaaaacg
    41581 cgtacctgtg acgccatcca tagtatctgc atgcgcgcct aaggtttcat acgggcgtag
    41641 gtgagtacct tcagataata gccaggcatc catttcctgg attagcgggc caaaacggta
    41701 aggatcatca atcaggtttt gctgaccatg ccagacaaca gccaactgat agcggaaaaa
    41761 attcttacgt cgcggaatga caccgctaaa gaatccccgt gagtcgagac actccagttt
    41821 tgcgagtttg cgcccggttt tcggttcaat cacccacaca tcggtagcgt cgggtaaaag
    41881 ggcacggact tccagtcccg cggtggtttt atgcatcccc agtacggaaa aaggatccgc
    41941 aaaatggcct gcaattagcg cgttaatcac gtctctatcg atacgatcgg acatgcttgt
    42001 cttcctgttt tattgtgtca ccccatccaa ctgaattttt gacttctggt tgtgacattt
    42061 ttttgacctg aacggcgcag cactctgtgc atcctctctg cgtcgtcctc acttcaggta
    42121 aggctgtgaa tactcgtgta ttccgccacc cttaaagaat agccaatgct ctatttaact
    42181 cccggtaaat catgaaacat ctgcgcttac tcctgtatta cgcactagca ggggcggcat
    42241 cgcgccccag atttaatgaa taaagattac gccagttgac gaagcatccg acgcagcggc
    42301 tccgcggccc cccacagcag ctggtcgccc acggtaaagg ctgacaggaa ctctggtccc
    42361 atattcagct tacgcagacg gcctaccggc gtggtcagcg tgccggtaac ggcagctggg
    42421 gttagctcac gcatagtgat ttcccgatcg tttggaacaa ctttcgccca cggattgtgc
    42481 gcagccagca gttcttccac ggtcggaata gacacatctt ttttcaattt aatagtgaat
    42541 gcctggctgt ggcagcgcaa tgccccgaca cgcacacata aaccatctac cggaattacg
    42601 gaagatgtgt tgaggatctt gttggtttcc gcctgccctt tccactcttc gcggctctga
    42661 ccgttatcaa gctgtttgtc gatccacgga atcaggctac ccgccagcgg cacgccaaag
    42721 ttatccaccg gcagctcacc gctacgggtt aaggttgtga ctttgcgttc gatatcgaga
    42781 atagcagagg acgggttcgc gagttcatca gccacatggc catacagatg gcccatctgg
    42841 gttaataact cacgcatatg tcgcgcacca ccgccggaag cggcctggta ggttgcaacg
    42901 gacacccaat caacaagatc attggcgaat aaaccaccca gcgacatcaa catcaggctt
    42961 acggtacagt taccgccaac aaaagtcctg atgccattat ttaatccgtc ggtaatgacg
    43021 tcctgattga cggggtcaag aatgatgatg gcgtcatctt tcatgcgcag agatgatgct
    43081 gcgtcaatcc agtaaccttg ccatccgctt tcacgaagct ttggatagat ttcgttggta
    43141 taatcgccgc cctgacaggt cacaatgata tcgagggcct ttagcgcctc cagatcaaag
    43201 gcatcctgaa gtgtgccagt ggttccgcca aaagacggcg cagcctgacc aagctgagaa
    43261 gtagaaaaga agacagggcg aatggcgtcg aagtcgcgct cttcaaccat gcgttgcatg
    43321 agaacggagc cgaccatacc gcgccagccg ataaaaccaa catttttcat aagcgttttt
    43381 tcctgcaaag atgtgtgctg tataaatgtg ccggtctcct cctggcacat ctttcaccat
    43441 acaaaaagca gccaaagtcg caagtgaaat taatcaatga tagcgaagcc atcagtaatg
    43501 cgacttatcc tgctttgtta gcacgcagaa agtccgcggc aattatcagg gaatttgagt
    43561 tatgaatgaa atcatttctg caacagtttt attgatcctg attatggatc cgctcggaaa
    43621 cctacctatt ttcatgtccg tactgaaaca tactgaaccg aaaagacggc gggcaatcat
    43681 ggtgcgagag ttgcttattg ctctccttgt gatgctggtg ttcctgtttg cgggcgagaa
    43741 aattctggca tttcttagcc tgcgggcaga aaccgtctcc atttctggcg gcatcattct
    43801 gtttctgatc gccattaaga tgattttccc cagcgcttca ggaaatagca gcgggcttcc
    43861 ggcaggtgaa gagccattta tcgtgccgtt ggcaattccg ttagtcgccg ggccgactat
    43921 tctcgccacg ctgatgttgt tgtctcacca gtacccgaat cagatgggac atctggtgat
    43981 tgctctgctg ctggcctggg gcggcacctt tgtcatcctg ctacagtctt cgctattttt
    44041 acgtctgctg ggcgagaaag gggtgaacgc acttgaacgc ctgatgggat tgattctggt
    44101 gatgatggca actcagatgt tcctcgacgg cattcgaatg tggatgaagg ggtaaggttc
    44161 aaacaggtgt tgcacacaac cagacgcggc acctgtttta ttacctgaac tgataatgac
    44221 cttcgcccaa tcggataacc cttccctctt cttctgcgcg gttcagccac acactaattt
    44281 gttcgatggt taaaccagta caagacgcca gcctttcaat acttatcgat tcctttgcaa
    44341 ggatcgccag ttccgccaca aagagttgat aaaaatcgac aggggtatgc gcgggcatta
    44401 ctgcgtaatt tgcgtcatct tcgtgcagcg aaaacagttc tggttgagcg ttacggagtg
    44461 ctctgtcata catcagccca ggaacgtctg gcagtctgat cgtcacattc tcagcctgtt
    44521 cagcactcca tgacgcccca ttttctacta atcgtgaatt ggctgattgc atatcctgat
    44581 ttggtttaac ctgcatgggc agccactgat gttttaatgc ctccatcgcc ccggttatcg
    44641 ttccaccggt cattcccgca cgtacaacca ttgcgctttc agcaaggcaa taaatatatt
    44701 tattccgcgc catcgcattg ccgacggtga aacgtacctc tgggtaaaac ggcgaaatca
    44761 acaccaggtt gcctgctata agcccttcac gccatttcac taacgtactc gtttttaaca
    44821 agctatcagc taatacgcca acggcagttc ccccgacctc cagagccgag gccattgcac
    44881 attcatcaat acctcgcgca ccaccagaga taacgcaaat cccctgttgg gccagtttcg
    44941 cggccagttg ttgggtatag cgcaaatcgt cagtcggagc atctcgcgag ccaacaatcg
    45001 ccataccttc cgcttgcagt aatgctttat tcccgcagcc aaataaaacg ggaggtgcat
    45061 ccgttcgcaa tcggtttttc aagcgaacgg gataatcggc atctccgcgg gttaagatcc
    45121 ataaaccggc gcgttgccac ttatctacag ccaacgccag actatgacca cgcgccagca
    45181 agccaagaat tcgctcctga gaaatacgcg gatcgctcca gcctgtaagt ttctcttgcg
    45241 gttgcggcac cagaagctcg gcgggactga tacgttggtg cttcagccat aatgcaaact
    45301 tcccccattc actattacta agaggtttat actcactcgc cgccgcgcga gaaaaatcgc
    45361 tggttagcag gagagttgct tgagcattgg ctgaaagatt catcaatttt ttaccgaggt
    45421 agaagcaagg gcaagaggat aaaccgtcgg gcaacctgcc tggcgtaaca gtgctgtcag
    45481 aactgtcagc gtccatgcag aatccacgat atcatcaacc agcaacgccg gacctggcat
    45541 caaaggaggg gtaatcacaa acgccccgtc gagattttga cactggtgaa aacggttttg
    45601 ctgcattttc tgcggtggat tgtccacgac tttttcaatg gcatcaataa aaggtaagcc
    45661 aagtttcgcc gccagtcgcc gggcaaaatc aggaaccagg tcgaggtgcc ttaatgaagg
    45721 aacgcagcat acccaggtgg gttcaggatg cggattccag cgttggcgaa ccatttccgc
    45781 acatgcctcc accagctcat cactgaagcg ccccgttttt ttctcctggg ctacctgctt
    45841 tccccacccg gaatctcccc aacgagaaag gattcgcccc gtagatcctt gtaaacccgc
    45901 aggcaagttc cctttaaatc cgtattgcgt aaaagcccca gatgccacct gtttattgag
    45961 atttaatggc aggtcagcgt gtttaataaa taaatttgcc gcatggagta agtcgctatc
    46021 aatgtcgggc gacaacagcg gatgctgaag acaactgcta catttaccac aacgttcggc
    46081 acttggctca tcgagtgcgc ggcgcagaaa ttgcattttg cactccttgg tcgtgatata
    46141 gctttcaacg tctgccaact cactttttct ctgattcatc aaatggttaa ttcgttcatg
    46201 atcaggagaa aaactgacga tagttctgcg ccataatttc tcggtataca ccacaggcga
    46261 tggattttca gctaccaata atttcagtgc tttttctatt tgcccataac gaagattcgt
    46321 ccgttgttca atgcctcgta gggtaagacc gtcattctcg ctaagtacgt tgagtatttc
    46381 atgaatttgc gcctccgcag gaaaggcgct ttcacggaag aattgatgaa tagcgcggtc
    46441 ttcaccacca caaagcaata tgccaactgc ggaatctata gcacgcccgg cacgccccac
    46501 ctgttggtag taaccgacaa tagaccccgg catctgataa tgaatgacga aacctaaatc
    46561 aggtttatca aatcccatac ctaatgccgt cgtcgcgacc agcactttga ttttatttgc
    46621 cagcagtgcc tgctccagat actccctggc agtattagaa tcttccgcac cttcacaagt
    46681 cacgccgctg taataagcaa atgcactgat accatttttc cttaaccact cggcgacaag
    46741 ttcagcatcg cgagtcgtca gggtataaac aattcccgat ttggaaaact gagggataac
    46801 cgttgctaac catgccagac gggatgactg ttctcctaag actaaggcat caagcgccaa
    46861 actttcgcga gccagcgttc cacgctgaat cacaatgtca cccaattgct gacggatatc
    46921 ctcaacgaca cggttattcg ctgtcgcggt tgtacccaga ataggggtat tcgcaggcag
    46981 ttggcgcaaa atatctaata tacgtcggta atccgggcgg aaatcgtggc cccaatcaga
    47041 gatgcagtgc gcctcatcga ccaccagtaa accgatgcgg tcagcgactg gatataaaac
    47101 cgtttcaaga aaatcctgat tcgccaaccg ttcaggtgaa atcagcagac aatctacgcc
    47161 accttgcagc aacttatcgc taatgcgctg ccattcttcc ctgtttgtag aattcaacgt
    47221 ttcagccgta atacctaacc gttcagcggc ggcaacctgg ttacgcatca gggcaagcaa
    47281 aggagagatg ataattgtcg ggccagcgcc gcgatcgcgg aagattttac tggcgatgaa
    47341 gtacacggca cttttccccc agccggtgcg ctgtacaacc agtagttttc gccgctgatt
    47401 aaccaccgca tctatagctt cccattgccc ttccctgaaa gtagcgctgg tgttacttaa
    47461 catccgctgt aacagcaatt cagctccgtg tttctccatc atcttctccc tcgtccgtta
    47521 acacagtgat tagaacggat aatgttccgg tctttttgcg agagagatca aaaagatgaa
    47581 gacaggagaa aagagaaatg aattactgcg agcaagctcg cagtaatttg tcgcagtaat
    47641 taactcaaca gctggaacgc aatcatccca acgatggcac cgacagtgcc gaggatggtt
    47701 tccatcatgg tccaggtttt aagcgtttcg gcttcggtcg cgccggtaaa tttaccgaac
    47761 aaccagaaac ccgcgtcgtt aacgtggctg acaacaatcg aaccaccggc gatacaaatc
    47821 gacagtgccg ccatttgcgc accggagtag ttcagttgtt caatgaccgg cattaccaat
    47881 cccaccgccg ttaaacaggc aacggtagca gaaccctgaa tgatgcgcac tgcagctgcc
    47941 agcacgaagc aggtgatggc aatcggcagg cccatgccgg ttaacgcttc gcccagtgcc
    48001 ggaccgacac cagagtcaac cagcacctgt ttgaacacgc cgcccgcacc aatcaccagc
    48061 agaatgatcc ccgccggttg cagcgcgtga ccgcaaatct ccatcacttt gtcttttggc
    48121 ataccctgac gcattgccag accgtaaatc gccaccaggc aagcaaccag aatcgcggta
    48181 aacggatgac caataaactc gaaccattcg taagcggtag aaccttctgg cacaaaacgc
    48241 gcggcaatgg ttttcagccc caccagcacc agtggcaaca ggatcagcga caggctgaat
    48301 ccgaaggacg gcattttgcc ttcgccgaga tgcggttcgc tgatgtcgtc aggaatatgc
    48361 aactccacgt agcggctgat gaaattaccc cacagcggcc cggcaataat cattcccgga
    48421 attgccgcgc acaggccaat caggatcatc cagccaaagt cggcgttcat ctgcgatgcc
    48481 agcagcattg gcgctggccc aggcaccagg aacgcagccg ctgccgccac gccggcgaat
    48541 aatgggatta ccagcttcac caggttcgtg ccggtgtggc gcgccattga gaaagcaacg
    48601 ctaatcagca gaacaatcgc cacttcaaag aacagcggta gcgcacaaac cagccccgca
    48661 aggccgatgg cataatgcac gcggctgtga ccgaaggatt tgagcatttt gacggcaatc
    48721 tgatcgaccg cgccggtttc atgtaagatc ttaccaaaca tggctcccag ggcgacaacc
    48781 accgccagga agccgagggt gcctcccatc cctttttcca tcgtcgctgc gattttatcg
    48841 agcggcatac cggaaaaaag gccagccccc atggacacca ccattaaagc caggaaagcg
    48901 tgcatacgcg ccttcatgac taaaaacagc agcagtaaaa cagaccctac tgctgttaaa
    48961 acaagcgtta atgtagtcac tacttatttg ccttttttaa taacctcaat ggtgcttgcc
    49021 acaacacctt ccagcggttg atcaatatcc accaccagta catcggtttc gtccgcaccc
    49081 ggctcctgca gcgtttcaaa ctgcgtcacc aacatttggg ttttaaagaa atggcctttg
    49141 cgcgctttca ggcggctttc aatcacatca aaatcgcctt tcaggtagat gaaagagaga
    49201 ttaggattac cttcacgcag caagtcgcga tagtgttttt tcagtgcaga acagacgatc
    49261 agcgatactt tattggtgcg ctgcatagca aacgcggcgt cgttcagcgc ctgcaaccac
    49321 ggtttgcgat cgtcgtcatt cagcggttcg ccagacgcca ttttttcgat attgcagcgc
    49381 ggatggagga aatcgccatc aagaaacgcg gcatgaagtt gatgcgccac ttcactggcg
    49441 accgcagatt tgccgctgcc cgatacgccc atcaagacgt aaatgtggtg atcatggtta
    49501 gtcgtgctca aagtggtgcc cccacaatac aagaattaaa aatgttacgg gtaactgtta
    49561 tcggtaacat tgtccagccg gacaatatca gaagcaatat ccatccgtgc cttaagtgta
    49621 taagtgtgag ctacttcaaa tttgtaggct taaatagatc cgcccggtga caaggtgaaa
    49681 cctaaatcta acattttcgg tgtcacagat tcgccacgaa tacgcgccag caggcgctca
    49741 gcgccaatgc tgcccatccg ctcacgcggc gtcagcacac tcgccagccg tggctccatc
    49801 acctgaccaa tgtcatgacc gtggaaaccg gcaatcgcca tatcgtcagg aactttcaac
    49861 cccagacgct gacattcaaa cgccgcgccg accgccaggt catcattagt acagaacacg
    49921 ccatccagct gcggatattc ccgccgcgcc tggcgaatca gttcaatacc ggaagagtaa
    49981 gaagaagatt gctcaaccat cacgctatac ggcaccaggc ctgcatccag catcgcctgt
    50041 tcgtatccct tctgtttgat gatagtacgt tcgtcgagac gtgcgccgag ataggcaatg
    50101 tggcgatgcc cgcgagcaat aatggcggtg gtcatctggc gtgccgcttc aaagttatca
    50161 aaaccgacgg cgatatcgag acacggcgac ttactgtcca tcaactccac caccggaatc
    50221 cccgccactt caatcatctt taaggtgcgt ggcgtgtggg tacgttcagt gaggatcagg
    50281 ccgtcgatat tccatgagag cattgattcg aggcgttctt gctccatttc cggtttataa
    50341 ccgtagtgcg ccagcatggt ttgataaccg tgcgcgtcgg tgacactttc gattccgcgt
    50401 aatacttccg cgaaaacctg gttggtgaga gaaggtaaca ggacgccaat cgcccggctg
    50461 gtggcgttag agagtatatc gggcgcgcga ttgggaatat aacccagttc atcaagagcg
    50521 gcggcaatct tgccgcgtag agcgacggaa acctgctccg ggttgcgtaa aaaacggctg
    50581 accgtcattt tggtcacgcc tacacggtca gccacatcct gaagtacggg tcttttcttt
    50641 ttcatcgtcc tgaaggtaca aaagagatag attctcttag tttaacacgg acgcatcaca
    50701 accttcctga ttcctcagga aggtttgtga gataaattta gactggcggt aaatcgaaca
    50761 gcaggatttc actgtcgcta tcagcatgga tggaaatcgc ctgctcatcc cagattgcca
    50821 gaccatcgct ggtcgaagct tttacgccgt taatggtgac attgcctttc accacctgga
    50881 tccagatgcg gcgttcagcg gcaatctgat gcaccgactg ctcatctttc accagcgccc
    50941 aacgatacag ttccatatcc tgatgcactt tcaatgaacc atctcgcgca tccggcgaaa
    51001 gcaccagttg tttgccctgc acggcatcga agcgacgctg ttcataacgc ggcgtaatac
    51061 cgttttcttc aggcatgatc cagatctgat acagatgcag acgctcggtg ctgcttgggt
    51121 tgtactctga gtgacgaata cccgtacccg cactcataat ctggaactcg cccgccggaa
    51181 cctgctcttt attgcccatg ctgtcctggt gctcaacagt accttccagc acgtaggtca
    51241 aaatttccat atctttatgc gggtgagtgc cgaagccctg ccctgcttca ataacgtcgt
    51301 cgttaatcac gcgcagcgca gagaagccca taaagttcgg atcgtaatag ttggcaaaag
    51361 agaaagtatg ccaggagtcc agccagccat gatttgcatg accgcgttca tttgctttgc
    51421 gtaagtagat catttgtatt cgccccctga atgatttcga tgggcttagt gtggacccga
    51481 tccgcctggg atgatagagg gtgaaaattg acccctctgt tcaaaaaaat tgaactattc
    51541 gaggggccat caaacttacc tcgcgagact cactgcggag ggagaagctt gctcaaaacc
    51601 gcgttcaagg atttccagat tcgtaagaac ttcagattcc ttgacgtaat ttggcgcacc
    51661 gttggtaatg gtttgataca acgcatcata aacgcgccca taatcgccca tctctggctt
    51721 catctcttct cttaccgtca cgccctcgtc attgacatac tccagcacac cgaccgaatc
    51781 atccgctgcg aatcctggtt cgcccggcat aatattagcc ttcaggctgg tttcctgctg
    51841 gtcgataccg tatttaataa acgaaccttt cttaccgtga acgataaatt tcggataatc
    51901 gattttcacc agatggctgg ttttgacgat ggcttttaga tcgccataaa acagctgcgc
    51961 ttcaaaggtg tcgtccggat tggctttatt acgcaggctg cggatgtcat aagcgacgtg
    52021 atccgggcga ccgaacagag aaataatctg gtccatcgta tgcacaccaa ggccatagaa
    52081 cgcgccatcc tgcggcagcc ccggtttggt ttctgccacc gggcggtaat agtcaaaatg
    52141 gctttccact tcgacaatct ctcccagctt gccgctttca atcgcttttt tcgctgtcag
    52201 gaagcaggaa tcaaagcgac gattctgata cggcgtaacg atcagccctt tgcttttcgc
    52261 cagtgcaaac agctctttcg cctgcgcaat tgtcggagtg aacggttttt cgaccagcac
    52321 atttttcccg gcttccagcg cgcgcttcgc gtactcgaag tggctgtccg cgtgggtgca
    52381 gacgacaacc agcttaacat cgggatcgtt tagcacttcg tcgagatcgc tggtgaaatg
    52441 gatatgggaa taaatggggg cctgttcttc cggcttcgca tggcggcgaa aaatatgcgc
    52501 gacatgccag ctatccttgc ggttaagtac atacggcaga tggtaacggg tggtgctttt
    52561 gccgaagcca ataaaggcgc agttaatgac catgatttcg tcctttttaa ggtggttatt
    52621 tacaccttag cgcaaagcgg acgtggttcc tactggagtg cgcataacga acacaagcac
    52681 ttcccgagga taaattgaga acgaaagatc aaaaaaaaag ccagcacccg gctggctaag
    52741 taatactgga agcaatgtga gcaatgtcgt gctttcaggt tctccgcgag ggtcttcctg
    52801 atcgcgagac aataataatc attctcattc gcacttgtcc aacacttttt gcaaaaaaat
    52861 gcatttgact cgcatttgaa agtcaatgat gttgaaaggg acatttaccc caaagaggac
    52921 aaaggaatga gtgagatagt aatacgccac gcagaaacac gcgattacga ggccatcagg
    52981 cagattcacg cccagccgga ggtgtattac aacacgctac aggtgcctca tccttcagaa
    53041 caaatgtggc tggaacgact caccgctcgc cctggcatca agcagttagt cgcctgtatt
    53101 gatggaatcg tcgtaggcca tctcaccatt gacgtgcaac aacgcccacg ccgcagtcat
    53161 gttgccgatt ttggtatctg tgtcgactcc cgttggaaga accgcggcgt cgccagcgcc
    53221 ctgatgcgag agatgattga aatgtgcgac aactggttgc gggtagatcg tatcgagcta
    53281 acggtgttcg tcgataacgc gccagcaatt aaggtctata aaaaatttgg ctttgagatt
    53341 gaagggactg gcaagaagta cgcattacga aacggtgaat atgtcgatgc gtattatatg
    53401 gcgcgtgtga aatagagaat ttgcaatcta cgtttgtcat ttaagccctc acctaccggg
    53461 agagggctta agatattaat accccgccgt taaatcatcc accgagcgcg ggtcggatgc
    53521 accgtacagc tcaccgtccg gcccaaccat aatgctttgt gtactgccca tcgcctcttt
    53581 cagcgccact ttctgacctt ttgcttccag cagcttgatc gtatccgggc taaacccttt
    53641 ttcgacacgc agctcgtccg gcaaccactg atggtggaaa cgcggcgcat tggtcgcttc
    53701 ggcgacgttc attccataat cgatgctatt caccaccatt tgcagcacag tggtgataat
    53761 ccggctaccg cctgggcttc cggtgaccag ccaggtttta ccatccttga ccacaatggt
    53821 tggtgacatc gacgacagcg ggcgtttatt cggcccgacg gcgttggcat cgccgcccac
    53881 cagcccgtaa acgttcggta cgcttggttt ggcggagaaa tcatccatct ggttattgag
    53941 caaaataccg ctctcgcccg cgacaatgcc cgtaccgaag gtggtgttca gtgtataggt
    54001 caccgccacg gcgttaccgt ctttatccac tactgagtaa tgggtagttt gattactctc
    54061 ataaggcgca agcttgccag gacgaatttc gctggatggc ttcgctttat tgatatcgat
    54121 ttgatcggca atagatttgg cataggcttt attggtcagc gcctgccacg gtactttgac
    54181 aaaatccggg tcgccaagat attccgagcg gtcggcgtag gcgtatttct cagcttctgc
    54241 catgatttgc atcgcgtcgg cgctgccaaa gccgtacttc tgcatatcga agttttccag
    54301 aatattgagg atttgtacga tatgaatacc gccggaagat ggcggtggca tggagtaaac
    54361 ctgatacccg cgataatcgc cgcttatcgg tgtgcgttcg accgctttat atgccgctaa
    54421 atcttctttg ctgatcaagc caccgttttt ctgcatctcc tgggcaatct gttccgctat
    54481 cgtgcctttg tagaattcat ccgggccgtt ttcggcaatc atctccaggc tctttgccag
    54541 gttcgcctgc accagcttgt cgcccttttt cagcggttcg ccctctttcc agaagatagc
    54601 tttgctgttt tcgtggttcg gcagcacttc actgccgtag gttttgagat cgtcagccag
    54661 cgcgtcgtta acgataaaac catcgcgtgc cagtttaaac gccggttgca ccactttatt
    54721 caacggcatg gtgccgtatt tatccagcgc caacgagaaa cccgctaccg taccgggtgt
    54781 gccggaagcc agatgcgaag tgagtgattt tttgctgtcc gtgttgccct gatcatcgag
    54841 gaacatatcg cgggtcgctt tggcgggtgc catttcgcgg aaatcgatag ccgtggtatt
    54901 gccatttttc gagcggatca gcataaaacc accgccgccc agattccctg cctgaggatg
    54961 cgttaccgcc agcgcgtagc ccaccgccac ggcagcatca acggcattcc cgccctcctt
    55021 gaggatatcc actcccacct gagtggcagt aacatctaca gacgccacca tcccttgttt
    55081 cgcgcgtacc ggatggaaga catcttcctc cacaccataa gaaacaggag gcgcggctac
    55141 cgtactaaaa caacttcctg tgagcagagc agcaatggcc acccggcgta aaaacgtcgg
    55201 ttttatcatc gttattctcc agagattaag gggcaacccc agctaagcct ggtatataac
    55261 tctgaattaa tcatcgtttt gccgggaagc gagtaaactt aaagaatatc ttcagaggag
    55321 gatacgcgat gaaacgactt ctgcttttga cggcactcct gccgtttgtc ggctttgcac
    55381 agcccattaa tactctgaac aaccctaacc agccgggata tcagatcccc agccagcagc
    55441 ggatgcaaac tcaaatgcag acgcagcaaa ttcagcaaaa agggatgctg aaccagcaac
    55501 tgaaaacgca aacgcagctg caacaacagc atttagaaaa ccagataaac aataattctc
    55561 agcgggtgtt gcagtcacaa ccgggggagc gaaatcccgc ccggcagcaa atgctgccca
    55621 acaccaacgg cgggatgtta aacagcaacc gtaatccgga tagttcgttg aatcagcagc
    55681 atatgctgcc ggagaggaga aacggcgaca tgctgaatca gcccagcacg ccgcagcctg
    55741 acattccgtt gaaaactatt gggccgtaaa gttcggacca atcacgtcaa tcgcatcggt
    55801 acagatgcaa tccacgcccc agcgcagcaa ctctgccgcg cgctggggtt tattgacggt
    55861 ataaaccaga attcgcagtc ctgcatcttt caactgcatc actcgcgctt tatcgagcaa
    55921 cttataattg agatgaatag agacgcagcc cagccgcgcg gtcaattctc gccagtcgtc
    55981 gcgccattca tcaagcaata aaccacgcgg cagttccggt gctgcctgtt gagcggcttc
    56041 taaagcatca atctcaaacg atgacagcag cggcggcgtc ataccggtcc acagttcgcg
    56101 tgccgccaac gccaccattt tgcccgttaa tggtccagtg tcagtggtgg gtttgatttc
    56161 gatattcgcc atcatcccgt gtttgcgaca gcgttccgcc acctgcgaaa gcaacggcag
    56221 tggctcacct ttaaacgctt tgctgtacca actgcctgca tccacgcgca gtaaatcctg
    56281 ccagttcagt tcacccgcga cgccccagcc gttgctggtg cgttcaagat tgtcgtcatg
    56341 gagcaggaag atctcgccat ctttcgataa cttcgcgtca aattcgatca tcttatgacc
    56401 gtattttgcc ccgacgtcga ttgctgccag ggtgttctcc ggggccagtt taccgccgcc
    56461 acgatgggcg acgatgcggg gataaggcca gttactcata ctcgttgtcc tgtttcacca
    56521 tcaaaaagat gtagctgatt ttccggcaga tgcagccaca gcgtgctgcc tgccgtcggg
    56581 cgctcctgat gtgccagtcg caccaccagc ttctgttcgc cccaatgtcc gtgcgccagg
    56641 ttatctgcgc cgaggatctc cagcgtgtcc atcaccagcg gcacaccacc ttctgcctgc
    56701 gagcttagcg ctatatgttc cgggcgaatg ccgagggtca ttttacgccc gacatactga
    56761 cggtagccac cgtttagcgg cagcgcaata ccgccatcca gttcgaaatg cgtaccttcg
    56821 ttattcacac ggccagccag taggttcatc gccgggctgc cgataaaact cgccacaaac
    56881 aggctggcgg gcttttcgta cacttcaact ggcgtgccaa tctgttcggc aacgccgccg
    56941 ttcatcacca ttactcgctg ggcgagcgtc atcgcctcaa cctgatcgtg ggtaacgtag
    57001 agtgaagtcg ttttcaggcg acggtgcagc tgttgcagtt caagacgcat ctgcacacgc
    57061 aacttggcat cgaggttaga gagcggctca tcaaatagga acactgccgg ctcacgcaca
    57121 atcgcacgcc ccatcgccac acgctgacgc tgaccgccag atagctcacg cgggcggcgc
    57181 ttaagcaggc cgtccagctc cagaatgcgc gccgcttctt taacacgttc ggcaatttgt
    57241 tgcttgccca tgccgcgaat tttcagcccc cacgccatgt tctcctctac gctcatatgc
    57301 ggatagagcg cgtagttctg gaacaccatc gcaatcccgc gatctttcgg ctccatttcg
    57361 gtgacacgct tgcggtcgat ccagatatcg cccgtcgtta cccgctccag tccggccacc
    57421 attcgcaata acgtcgattt cccgcagcca gacggcccga ccatcacgat aaattcgcca
    57481 tccgccacat caagggtcag cggtttaatg acctgggttt tgccatccca gcttttggtt
    57541 actgcctgta atttcagtcc tgccatctta tttctcacta tcgaccaggc cgcgcacgaa
    57601 ggcacgctgc atcactaaaa caatcactac tggtgggatc agggttaaca acatcgccgc
    57661 catcaccgag ttccattccg ttgtgccttc gcctgtggcg atcatccctt taatccctgc
    57721 cacggtggtg ccgagatcaa cgtcggtaat aatcaacaac ggccacaaat actggttcca
    57781 gccgtaaata aaggtgatca caaacagcgc cgccagattg gttttggaca gcggaaaaac
    57841 gatgtcgcaa aagaaacgca ttggcgacgc gccgtcgatc cgcgcggctt ccaccagttc
    57901 atccggtagg gtcataaaga actggcgaaa cagaaacgtg gcggtcgccg aggccatcag
    57961 cggcagcgtt aaacctgcgt agctgtcgag cattttcagg ttggcgatga cttccaccgt
    58021 cgggaagata cgcacttcaa ccggcagcat cagggtgata aaaatcatcc agaagaagag
    58081 gttacgtagc ggaaaacgaa accagacaat ggcaaatgcc gagagcatcg agacggtaat
    58141 tttgccgagc gtaatgctga acgccatcac aaagctgtta agcaacatcc gccagaacgg
    58201 cgcgctattc gtgcctaccc cgtttaccca gatgttgtgg atgttttcca gcagatgtgt
    58261 gccgggaata agcgtcatcg gcgcggcgta gacttcttgt ttatccagcg tcgccgcgac
    58321 aaacgccacg tacagcggga agaggatcac cgcgatcccg aggatcagca tggtatggct
    58381 gaatattgtc agccacggac ggttctcaat cattggtaac gtaccttgct ttcaacatag
    58441 cggaactgca ccaccgtcag cacgatgacg aggaacatca acaccaccga ctgcgcggca
    58501 gacgaagcca aatccagtcc ggtaaagcct tcacggtaga tcttataaat cagcgtcgtg
    58561 gtggcctgta ctggcccgcc ggacgtggcg gcgtcgatca ccgggaaggt gtcgaagaag
    58621 gcatacacca ggttcaccac cagcaggaag aaactcaccg gagcgataag cggcagcgca
    58681 atcttaaaga agcggcgaat cgggccagcc ccatcaatgg ctgcggcttc gatcaacgaa
    58741 cgggggatgg attgcagcgc ggcatagaag aacagaaagt tgtagctgat ttgcttccac
    58801 actgaggcaa acaccaccag gaacatcgcc tgaccgctgt tttgcgcgtg gttccagtcg
    58861 tagccgaact cagcgagaaa atgggtgatc agcccgcgac cggggttaaa cagaaagatc
    58921 cacaatacgg cggcaacggc gggagccacg gcatacggta gcaacatcaa ggtttgatag
    58981 aaacgactgc cgcgcacgat gtactccacc agcgctgcga agaacagcga taccagcaaa
    59041 ccgctgacgg tgacaaaggt gctgaatttt atcgtcgtcc agaaggcgtc gagatagtag
    59101 ctgtcgtgaa acagcgtgac gaaattatcc aggccgacaa actggctgga gaaaccaaac
    59161 ggatcgacgc tttgtagcga gtaccacaac gcttcgcccg caggccagat aaaaaagata
    59221 acggtgatga tgagctgcgg cgcgaccagc aaataaggta gccagcgcga gcggaacacc
    59281 ggacgggatg atggcattac tgttaattcc tgaactgtgc cggatgcgct tcgcttatcc
    59341 ggcctacacg cgatgccagg tcagataagc gaaacgcatc cgacattaca ctgattaaga
    59401 cttcgtcgat ttctcaaagc ggcgcagtaa ctggttccca cgctcaacgg cagtatccag
    59461 cgcctgctgt ggtgtcttct taccggtcca cacgctctcc agctcttcat ccacaatcac
    59521 gcggatctgc ggcatgttgc ccagacgcaa acctttggtg aacggcaacg gtggcttgtt
    59581 cagcatctga cgcgtggcaa tatccgctcc tgggtttttc tcgtaaaagc cctgctcacg
    59641 ggtcaggtca tacgccgctt tagtgattgg tagataaccg gttttctgat gccactcggc
    59701 agcgttttct ggttttgcga ggaagtcgag gaacttcgcc acgccggtgt aagtttcttt
    59761 atctttaccc tgcatcaccc acaggctggc cccgccgata atggcgtttt gcggcgcgtc
    59821 tttcgcatcg gcgtcgtaag gcatcatgcc tacgccatag ttaaatttgg cgtactcgcg
    59881 aatgttggca agagaaccgg aagaggcggt cgtcatcgcg caatcaccgt tatagaactt
    59941 ctcggtggat tcatccttac gcccaacgta gctgaaatcg cccttcttgt tcatctcttc
    60001 gagcatggcg atgtgtttca cctgctccgg cttgttgaac tcaagcaccg cgtctgtgcc
    60061 gtcaaagccg ttgtttttgc tggcaaacgg cagaccgttc caggcgctaa agttttccag
    60121 ttggatccag ccctgccagc cgctggcgta gccgcacttc atgccggagg cttttagttt
    60181 tgcggcatag tccgccagat cctgccaggt ttttggcggc tgttccgggt ctaatcctgc
    60241 tttcttgaag gcgtctttgt tgtaatagag aacgggggtc gaactgttga acggctggga
    60301 aagtaagtgc ccagttttgc tgtcggagta gtaaccggaa accgtcggca caaactgcga
    60361 ctcatcgaat tgaatccttg cctctttaaa tacgtcatac accggtttaa tggctttcga
    60421 cgccatcatg gtggcggtgc caacttcata aacctgcaaa atagccggag cgttgccggt
    60481 acgaaatgcg gcaatccccg cgcttaaatt ctgttcgtaa ttgcctttat aggtcggtac
    60541 aattttgtaa tccgggtttt cggcgttaaa acgttgggcc agagaatcca cctctttacc
    60601 cagttcccct tccatagaat gccagaacgg aatggtcgtc actgcctgcg catttgccat
    60661 taaagccagt ccgagcgcca gtgctgaagc tgtataacgt aacggtttca ttgattatct
    60721 ctcttgttgt accgaatgcg cgaattcacg cgttttatgc tcgcggagta acatgacatg
    60781 ctcgaattac agaaaaataa ctattttgtt acatttttaa gatagtaagg tgtcagaaag
    60841 atgacaaggc ggtgacggcg cgggcgaggg aaaatgggag atggggcacg gataagcgga
    60901 aaaatagaag gtctgaatca aactctacag attactcatc gtttcatgcc ggatgcggcg
    60961 taaacgcctt atccggccta caagatcgtg caaattcaat atattgcaac tcacccagta
    61021 ggcctgataa gcgcagcgca tcaggcaatt ttacatttgt cacctgtctc aaaggagtct
    61081 tttgactcct tatcaatcaa cgtgttatta cccgcctaaa tatgcacttc tcactgcttc
    61141 attcgccagc agcgcgtcgc cggtatcgga gagcactaca tgaccgtttt ccagcacgta
    61201 gccgcgatca gccagcttta gcgcctggtt ggcgttctgc tcgacgagga agatggtcat
    61261 cccctgctcg cgcagttgtt cgatggtgtc gaaaatttgc tggatgataa tcggtgccag
    61321 cccgagcgat ggctcatcaa gcagtagcaa acgcgggtta ctcatcaaag cgcgaccaat
    61381 cgccagcatc tgctgttcac cgccagacat agtgcccgct cgctgaacac ggcgctcatg
    61441 cagacgcgga aacagttcat agacccactt tatgcgctcc tggaactggt cgcgttcggc
    61501 aaaaaagccg cccatcgcca ggttctcttc caccgtcatc cgcgagaaga cgcgacgccc
    61561 ttccgggaca atcgctaccg cttcgcgcat gattttcgcc gtctgccagt cggtaatgtc
    61621 tttatcatca aacacaattc gcccgctggt ggcgcgcgga tcgccgcata acgtgccgag
    61681 caaggtggtt ttccccgccc cgttcgcgcc aatgagggtg acaatctcgc cctgattgat
    61741 atgcaggctc acctcatgca gcgcctggat tttgccgtag tgggcgctga ctttgtcaaa
    61801 ggacaacatg actttttcca tcttatgcct cacctaaata ggcacggatc acatctgggt
    61861 tattacggat ctgctccggt gtaccgtttg ccagcggcat cccctgattg accacgtaaa
    61921 ttctgtctga aatccccatc accagcttca tatcgtgttc aatcaacaag atagtggtgt
    61981 tgtgatggtt acgcagttcg gcaatcagct catccagctc tttcgtctct ttcgggttaa
    62041 gacctgctgc cggttcgtcg agcattaaaa tctccggctg cgtcaccata cagcgggcaa
    62101 tctccagacg gcgctggtca ccataggcca ggttactcgc ctgacggttg gcatgttcca
    62161 gcaaaccaat gcgctcaagc caggtggcgg cgcggtcgag cgcttcgctc tgggcgcgac
    62221 ggaaagaggg ggttttcaac aggccggaga acagcccagt tttcagttgc tgatgctgtg
    62281 ccaccagcag gttttcaatc accgtcattt cacggaacag acgtacatgc tggaaggtgc
    62341 gcaccacgcc catgcgggca atttgctgcc ccggtaaacc ttccaggtgc tgatcgcgca
    62401 gtaaaatggt gccgccggtg ggtttataga atccggtcag gcagttgaag accgtggttt
    62461 ttccggcacc gttagggccg attaacgaga cgatctcctg cgggtacagt tcaagattga
    62521 cgttgttcac cgccagcagg ccgccgaagc gcatcatcag gccgttaaca gataataatg
    62581 gctgactcat gcctgctctc cttttgctgc gccgtttttc agcttgagtt gcgggcgcgt
    62641 catgggcagc aagccctgcg gacgccagat catcatcagc accatcaaac caccgagcat
    62701 taacatgctg tattcgttga aatcacgcat caactcgcgc gataccacca gcaaaacagc
    62761 cgcaagaatc actgcaaatt gcgagcccat accgccgagc accactatcg ccagcacaaa
    62821 cgccgattcg gcaaaagtga aggattcagg gctgacaaag ccctggcgcg cagcaaacaa
    62881 cgttccggca aaaccggcaa acgcagcgct gatggtaaag gcagtcagct tgatacgacg
    62941 cgggcttaag cccagcgaac gacaagcgat ttcatcttca cgcaacgctt cccacgcacg
    63001 ccccagcggc atccgcagca ggcggttaat gacaaacagg cttaacacca ctagcagcaa
    63061 cgccaccagg tagaggaaga tgacgcgatc ggagggatcg tatttcaggc caaagaaatt
    63121 gctgaacgtg tcccagccgc cttcgcgggc ggtacggctg aactcgagtc cgaagagcgt
    63181 cggtttcgga atctgactga taccgttcgg tccgccggta atttcggtgt tattgagcag
    63241 caatatgcgc acaatttcgc cgaacccgag ggtaacgatc gccagatagt caccgcgcag
    63301 acgcagcacc ggaaaaccga gcaggaagcc cgccgccgcc gccattaacc cggcaatcgg
    63361 cagacaggtc cagaagccca ggccgtaata gtgattgagc agcgcaaaag tgtaagcgcc
    63421 gatggcgtaa aagccgccgt atcccagcac cagcagacca gaaagaccaa caaccacgtt
    63481 cagcccgaga ccgagaataa tgtagatcat ggtcagagtg gcgatatcca ccgtcccacg
    63541 cgacaccata aacggccacg ccactgcaag caccagcagc gccacgagga acagtttctg
    63601 cttcaccgtg gagccatcaa tcgcgggcag aataaacttc ggcccggaaa cgctttttag
    63661 ccctttctgg aaagcaggcc gcacaagctg gaagaaaaag accaccgccg tgccgataaa
    63721 cacccactgc caacggatct ctgaagccgt gtcgaccacc agtttggtgc catccagctc
    63781 cagttgcacg cccataaaga cgcccgccag cacaaagaac atagcggcag agagcagcgc
    63841 cattgcaata tgcatcggtt tcatactttc tctacctccg ggcgacccag aataccggtc
    63901 ggcatcacca gcagcaccag gatcagcagg gcgaatgaga ccacatcttt atattccgta
    63961 ctcagatagg cagaagagag cgcctccgca atccccagga tcagcccgcc aatcatcgcc
    64021 cccggaatgc tgccaatccc accgagcacc gcagcggtaa aggctttcat cccggccata
    64081 aagccgatgt aggggttaat tacgccgtag aactgaccga gcagcacgcc cgccactgcc
    64141 gccatcgccg cgccaatcac aaaggtcagc gcaatcaccc ggtcggtgtt gatgccaagc
    64201 aggctcgcca ttttcagatc ttccgcgcag gcacggcagg cgcgccccat acgggaatag
    64261 cgaatgaaaa tcgtcagcgc cagcatggcg aggaaagtaa caatccatat caccgcctgc
    64321 atggtggtaa tagacgcaga gaagttttcg ctatggccca ccacccactg accgttaaac
    64381 aggctgggca gcgccacatc gcgcgaacct tcggtcaggc tgacgtagtt ttgcaggaag
    64441 atagacatgc cgattgccga gatgagtgca atcaggcgct tagagttgcg caccgggcga
    64501 taggctaccc gttcgatact ccagccgtag gcgctggcaa tgacgattgc gccgacgaat
    64561 cccgccgcca ccagcagcca gccggtatca atgcccagca tcatcagtgc ggcgatgatc
    64621 ataaaggaga cgtagctgcc aatcatgtaa acctcgccgt gggcgaagtt gatcatgccg
    64681 ataatgccgt aaaccatggt gtagccgatg gctatcagcg cgtaggtact gcccagcgtg
    64741 acgccgttaa acatctgctg caagaaatac aaaaactgct cagacataag gtaacctttc
    64801 taaacccgcc cgtttttcac ggacggtggg atgatcactt ggctgccgtg gatgaaccgt
    64861 cggcgtgcca ctggaagaca ccaaaatcga atcccttaag atcgcctttt tcatcccagt
    64921 tcagcggccc aattacggtg tttgcaccgt tagcttttaa atctttcacc agcgccagcg
    64981 gctcatcgct gccggtacgt tcaagggcag ttgccagaga ttgcaccgcc gcgtaggtga
    65041 tccagacata gggcccggac ggatctttct tgtcggcttt cagcgcatca acgatgccct
    65101 ggtttgtcgg atcctggtca tagcgttttg gcatggtgac caacatgcct tcagcggcat
    65161 caccggcaat gttcgacagt gacgcattac cgacaccttc cggccccata aactgggttt
    65221 tcaggccaac ggaacgggcc tggcgcagca tctgccccat ttccgggtag taaccgccgt
    65281 agtaaacgaa gtcgatgttt tcttttttca ggcgggcgat cagcgcggag aaatctttct
    65341 ctccagcggt aatgccgtcg aagaagacga cgttggcgtt agccgctttc agcccgtcct
    65401 gcaccgaacg tgccagccct tcgccatact gttgtttgtc gtgaatgatg gcgatgcgct
    65461 ggggcttcac cgtctcaaga atgtattttg ccgccgttgg cccctgggaa gagtccagcc
    65521 cggcagtacg catgatgtat tgataaccgc gttgggtcag ctccggattg gtcgctcccg
    65581 gcgagatcat cagaatacct tcgtcttcat agatatctga tgcaggttgg gtagaggagg
    65641 aacacaagtg cccaataacg tatttaatgc cgtcgttaac gattttgttg gcgaccgcaa
    65701 cggcttgttt cgggtcgcag gcgtcgtcat attccacgcc aaccagttta tcgcccttaa
    65761 ttcccccttt ggcattaatg tctttaattg cctgacgcgc gccgttaaat tccatatcgc
    65821 cccactgggc aatcgggccg gacatcgcgc cgacaacggc gactttaata tcgtcagcca
    65881 tagcggtgtg tgaaattgcc agtgcaatca tccctgcgat gatagttttc gcattccgtt
    65941 tcatagtcaa aaatccccat tcgtgatgtt gtgttgcttt gttcttatgt gttaacaaat
    66001 cagactgttc ttttttatac tgcactgttt ttacctgtct gattaagggt ttagcgcagt
    66061 attttgtgat gatagcgatt aaaatcccta tttttcagtc gattaagaac agataatatt
    66121 ctgaatttat tgatagataa acagaaaaaa gcgccgttgt cagcataaaa taacggtaca
    66181 aagggcagaa taattcacta ccatttaggg gattatgctg gatatttttc attctctaat
    66241 gttttaactt tgtaattatt gctgaaaaaa aattaatcac ctgccaaaag aaataaaaaa
    66301 gagaaagcct ccgattaaat tatttcgcta cactggttcc acttttgtga tttacacggg
    66361 ttccccatga agctgaccat cattcgatta gaaaacttta gcgaccagga ccggattgac
    66421 ctgcaaaaga tctggccgga gtattcccct tcctctttac aggttgacga taaccaccgc
    66481 atctacgccg cgcgttttaa cgagcgcctg ctcgctgccg tgcgggtaac cttaagcggc
    66541 accgaggggg cactggattc tctacgcgtg cgggaagtaa cccgacgtcg cggtgtgggg
    66601 caatatctgc tggaagaggt tttgcgtaac aatcctggcg tttcatgttg gtggatggcg
    66661 gatgctggcg tggaagatcg cggcgtgatg acggcgttta tgcgagcact gggatttacg
    66721 gcacaacagg gtggctggga gaagcgttaa tcgtctggtg taaaaagtag ctctatagat
    66781 ttggtcggga aaaataacgc attttcgttt tctccgacca atgggataaa gcccagcgac
    66841 tgataaaacg tatgggcttt ttcattcagc gcctcgacaa aaagaccgtg aatacctacc
    66901 gctaaagagg ctgaccagac aactttcatg gcatgagcaa ccagtgttgc tccccatccc
    66961 tgcccctgta atgaacgatc aattgccaga cgcccaagag ttacgctggg aatatttttg
    67021 tagggaattt ttttctgttt cgatttcgag ggcagtgcgg ctcgttcaaa acaactgccg
    67081 gataatgtgt aatatcccag cacctgacgt tctggagtgt tgcgacacag gatatacgct
    67141 cgcagaattt tattgcgatg ttgacgaacc agatgtgtcg tcagaaagag atttaatgct
    67201 tcctcgccgc agtcgaatcg ctgtagatca taatctgcat catcggtcag aatctctatc
    67261 gtcagatcat ccataaagta ttacattccc tgaagacgtt ttgccgcacg ttttagcttt
    67321 tcacctggtg acggtggatt actcagcgca tccatcaccc gcgtccagga ttcctcagtg
    67381 agaatcatcc gccgatgctg ttcaatcact tccgcagctc gctgcgaagc gctgttcaac
    67441 ataaattggc tgacggactg attagatatc gctgccgctt cctcaatcat acttttgtca
    67501 tcgtcagtta aacgcagatc aatacgctgc tttttaacag cagacatgtg aactctcctg
    67561 ctccgtataa tatgtacggc atatcaccgt acataagcat atcctgaatt gttcaatctt
    67621 tctacaacca tttcgataaa tataaaaaaa cccgatggca gttcagcgca tcgggtattt
    67681 tcatttatct atctgttact tcgcatcagt cgccgtgccg ttggcgtgcc agtcaaacac
    67741 accgaactca aagcctttca gatcgccttt ctcatcccag ctaagcggcc ccatcaccgt
    67801 atcaaccgag ttcgctttca ggtatttagc gatctccgcc ggatcgtcag actgattcag
    67861 ccccgcttgc aaagattgca gcgcggcgta ggtggtccag acgaacgcgc cgcttgggtc
    67921 ctgttttttc gctttgatcg cgtcaacaat cggtttgttc gccggaacct gatcgtagtt
    67981 cttcggcttg gtcaccagca gcccttccgc tgattcgccc gcaatgttag acagcgagac
    68041 gttagccacg ccttctggcc ccataaactg agttttcagc cctgccgcgc gtgcctgacg
    68101 caggatttgc cccatttccg ggtgataacc gccgtagtaa acgaaatcga tattctcttt
    68161 cttcaaacgc gccaccaggg tagagaaatc tttttccccg gcggtgatgc catcaaagaa
    68221 caccacgtta gcattgcctt tcttcaggcc gtcctgcact gcacgcgcca gaccttcgcc
    68281 gtactgctgt ttgtcgtgaa cgatagcaat gcgttgcggt ttcactttct caagaatata
    68341 tttcgccgcc gtcggcccct ggtcggagtc caggccggtg gtgcgcagga tcagctgata
    68401 gccacgggcg gtcagctctg gtgcggttgc cgctggggtg atcattaaaa tgccttcgtc
    68461 ttcgtagatg tcagacgctg gctgcgttga tgaagagcag aggtgaccaa tcacgtattt
    68521 aatgccgtcg ttaacgactt tgttcgccac cgcaaccgcc tgtttcgggt cacaggcatc
    68581 gtcatatttt acgatttgca gtttgttgcc tttgataccc cctttagcat tgatatccgc
    68641 aaccgcctgc tctgcgccag taaactcctg gtcaccgtac tgcgccaccg gaccggacat
    68701 tgcgcctacg acggcgactt taatatcttc tgccagagcc atattgctga atgccagcgc
    68761 gatacatcct gccagtaacg ctttaccctt tatgttcatc ctgagaatcc ccactcttct
    68821 ggttattacg tgtgttgtga tgttgttgtg cagcacttta tttcgtttta tacgtagcta
    68881 cccgtgcttt agcagcatac tctgctaaaa cataccccat ttttatgata ttggaatagc
    68941 tattttgaca gtttattaac aatctgcgtg gggattggcg ttttgccgga gggggaattg
    69001 attattgtag aggcccaaaa aacaaaaacc ccggactctc atccagggtt ctctgcttaa
    69061 tagcggaaat tacgcttcaa tagcagcgcg caattttttc atcgcgttct tttccagctg
    69121 acgcacacgc tcagcggaaa caccgtaacg gtcagccagt tcctgcaacg tggacttgtt
    69181 gtcttcgtcc agccagcgcg cgcggatgat atcctggcta cgctcgtcca gaccttgcat
    69241 cgcgtcggtc agacggtttg ccgcctgctc ttcccagtta tcatcttcga tgccgtcggc
    69301 aaagttagat gatttatcct gcagatagag caccggagcc atcggctggc tgtcggaatc
    69361 gtcgtcggaa gacaggtcaa aggtcatgtc ctgtgccgcc atacgtgatt ccatctcacg
    69421 tacgtctttg ctggttacgc ccagttcacg ggccaccatc tcgacttcat cctggttaaa
    69481 ccagcccaga cgctgcttgg ttttacgcag gttgaagaac agtttgcgtt gcgctttggt
    69541 ggtcgcaact ttgacgatac gccagttacg cagaacgtat tcgtggatct ctgctttgat
    69601 ccagtgaacg gcgaaggaga ccaggcgcac acccacttcc gggttaaaac ggcgcactgc
    69661 tttcatcagg ccgatgttac cttcctgaat caaatccgcc tgtggcaggc catagcccgc
    69721 ataattacga gcaatatgaa caacaaaccg caggtgagac aggatcagcg ttttagctgc
    69781 ttccagatcg ccatggtaat gcagcttttc agccagcgcc cgctcctcgt cagccgacaa
    69841 catcggccac gcgttagctg cccggatgta ggaatccagg ttgccaactg gggctaaagc
    69901 taaactttgc attttgtcag tcattcaaat cctctcaatc gatatcttct ggcgcttcag
    69961 tggtagcaac aactgtgcca gagcttaaga gcaacgaggt tatcattcac tgttttatca
    70021 gaccgtgatt ttatccacaa gttcaatgca agtttgtgaa taaattacgc acaaaatgtg
    70081 acatagagat aaaataccgg gaagagacaa cggggtctct ttccctgcta cggaatccat
    70141 tgcagggaaa gagtataaca cgcttttatt attcaggcgt aaagtggcgt aaatgttgta
    70201 ccgtggcaag ccacgctgcc acccagccaa tcatcgagca taccagcagc aatagcaggc
    70261 attcatcgaa cgataagcca ttgatatcaa acttcgttcc gaaaacctgt gccacttccg
    70321 caaccgccga tgacaaacgc agcaccagaa tttctgacaa aattagtgac aacaatgcgc
    70381 cagaaaatcc cagcaatgcg ccaccgtaca ggaacggacg caggatgaaa ccatccgtcg
    70441 caccaatcag tttctgcacg ttaatagaat cacggcgagc aaagatactc aggcgcacac
    70501 tgttaccgat gacgaggaat actgccgcca ccatcaatac gccgatcatt gccgaaacgc
    70561 gcccgaccag cccggtcaac gccgccaggc gggcaaacca gctgtcatcc atccgcactt
    70621 cgtcaatgcc gttaatctgc gtgatacgat cacgcagcgt attcagtgac tccgtcccct
    70681 gaaaatcgag tttcgggatc accaccgcca ctgccggaag cgggttttct tccagcatat
    70741 ccagcgcacc accaaaacca gaccagttac ggaactcgcc cagtgcgtct tcacgagaaa
    70801 gataattcac tttctccacg ccttgctcgg cctgcaactg tgccaccacg cccgcagcgg
    70861 cgtcatcatc cagcgttttt tgcagataaa cagtgatttg cggtgacgga taatattgcg
    70921 tcgccgcctg gttaacgttt ttgtacacca tataacagac gctgggcagc gtcagggaga
    70981 tggcgataac catcaccgtt aaaaacgtgg cgaacggttt gcttttcaga tcctgcaatg
    71041 cgccgtggga ggcatagcgt acctgttcgt tgaaaacgtt ggttttgcga tttaccggtt
    71101 ttggcgagga tttcgcgcgt ttcggcgcgt tacgaccgcc gtcgccagag ccgccgaccg
    71161 atttacggaa gcgatccaga cgcccgccaa actgccgaat gtgattgatt gcatcgcgct
    71221 tattcatggc ccacgcctcc atgcaagtga ccatcgctca gggtgagcat gcgataggaa
    71281 cgtcgcgaaa tcaggttgat gtcgtgcgtt gccatcaata cggttactcc aacgcggtta
    71341 aactcttcaa acagacgtaa aatgccttcc gacagcgcgt cgtccaggtt accagtcggt
    71401 tcgtccgcca gcagtaccgc gggcttgttc accaccgcgc gggcaatgcc aacacgctgt
    71461 tgttcaccgc cggaaagctg aatagggaag ttcttcgctt tgtccagtag cccgacttta
    71521 tccagcgccg ccgacacccg gcgacgaatg tcatcaccgc tggcaccggc gataatcagc
    71581 gggatcgcca cgttatcata gacagtacgg tccatcagta gatggtgatc ctggaaaatc
    71641 atgccaatct ggcggcgcag aaacggaact tcacggtttt tcagacgcgt gatgtcatgg
    71701 ccgctaaacc agattttccc ggcgctgggc cgctcaatcc cacagatcag cttcaggagg
    71761 gtacttttcc ctgcgccgga atgaccggtc agaaacgcca tctcacccgg ctgcatatgg
    71821 aacgtaacgc cctgcagcgc ctgtctccca ccgagataag ccttgctgac atgttcaaag
    71881 cgaatcattg ttaatcctct cgggcaaaaa gtgcctctat aaagtcgtcc gccttaaacg
    71941 gacgcaaatc ctcaatacgt tcgccgacac caatgtagcg gatagggata ccaaactggt
    72001 cagccaccga gaaaattacc ccgcctttcg ccgtgccgtc cagtttcgtt agcgtgatgc
    72061 cggttaagcc aacggcttcg tggaacagtt tggcctggct taccgcattc tgcccggtgc
    72121 tggcatcgat ggtcagcata acttcatgcg gagcttcaac gtcgagtttc ttcatcacgc
    72181 ggacgatttt cttcaactct tccatcaggt gcgatttgtt ttgcaggcgt ccggcggtat
    72241 cggcaatcag gacgtcgatg ttacgcgctt tagcggcctg aatggcatcg aagataacag
    72301 aagcggaatc cgcaccggta tgctgggcaa tcaccggaat attgttgcgc agaccccaga
    72361 cctgaagctg ttcaaccgct gccgcacgga aagtatcgcc tgccgccagc atcaccgatt
    72421 taccctgctg ctcaaactga cgcgccagct taccaatcgt cgtggtttta cccacaccgt
    72481 tgacgcccac catcaggatc acgaacggcg ttttaccttc aacattcagc ggctcatcga
    72541 ctttcgccag aatctcgccc atctcttctt tcagcaggcc atagagcgcc tcggcatcac
    72601 gaagctgctt gcgggatgcg ccttctgtca gattggtgat aattttacga gtggtttcca
    72661 cgcccacatc ggcgatcaac agctgttctt ccagctcttc aaacagatca tcgtcgattt
    72721 ttttaccgcg gaacaggctg ataaatccgg aaccgagatt ttctttggtt tttaacaggc
    72781 tgcgtttcag gcgcgcgaag aaaccttctt tggtcggttt ttcctgctcc tgagcgattt
    72841 cttccaccgg ctgatcttct tctgccggag aaaccaccat taccgcctct tctgccactt
    72901 cggcagccag cgcctgtgcc tccggctctt cgtcggtgat ttcttcttta gccgcttctt
    72961 cttccgccgc ttcgacaatc tctacggttt ccgcttcggc ctgccactct tctggcgaaa
    73021 ccgcttcggc gttgacgtct tccggcaacg gcagttcttc acgttcgata gccactggct
    73081 ccggcgtttc ttctacgacc ggttccggct gtgcaacgac ttccgcttca ggctgcgctt
    73141 tttcactttc agcaacctgt tcagtaactt ccacaacgtc ggcagcaaaa gtttccgcct
    73201 cggcttcagt atgcgcctgc ggctgctctt caacggcttg ttcagaagcc ttcacaggct
    73261 cttgctcctg aacgatttct tctacaactg gttgttcatt ctgaacttct gtctcttttt
    73321 ccggggtctg ctctttttga ccaaagccca gccaggaaaa aaagccacgt tttttttctt
    73381 tcgccatttg cgactacact cctcgctgtt gcttcatggc acagcgttaa cgctatgtac
    73441 atagcagcta aaaaaatgat gaaatagtct atcacttaac ttaattcaca tcaccgcctg
    73501 caagtatgtg ttatctggcg gattgagcaa tttatcatga aaaaaccgaa tcattccggc
    73561 agcggccaaa tccgcattat tggcgggcag tggcgaggcc gtaaactccc ggttcctgat
    73621 agtccaggtc tgcgccccac caccgaccgc gtacgcgaaa cgttgtttaa ctggctggct
    73681 ccggtcattg ttgacgccca atgtctggat tgcttcgccg ggagcggcgc gctggggctg
    73741 gaagcgttat cgcgctacgc tgcgggggcc acgttgattg agatggatcg tgcggtttct
    73801 cagcagttaa ttaagaatct ggcgacacta aaagcaggca atgcacgcgt ggtgaacagc
    73861 aacgcgatgt cattcctggc gcaaaaaggc acaccgcata atatcgtgtt tgtcgatcca
    73921 ccgttccgcc gtggcttgtt agaagagacg ataaatttac tggaagataa cggctggctg
    73981 gctgacgaag ccctgattta tgtcgaaagc gaagtcgaaa agggtctgcc cactgttccg
    74041 gcaaactggt cattacatcg ggaaaaagtg gcgggtcagg tggcttatcg gctgtatcaa
    74101 cgcgaagcac aaggagaaag tgatgctgat taatattggt cgtttgttaa tgctctgtgt
    74161 ttggggattt ttaatcctca acctggtgca tcccttccca cgcccgctga atattttcgt
    74221 taacgtggcg ctgattttta ccgtgctgat gcatggtatg cagctggcgc tattgaaatc
    74281 cactttaccg aaagatggcc cgcagatgac caccgccgaa aaggtgcgga ttttcctttt
    74341 cggcgtgttt gaactgctgg tctggcagaa gaaatttaaa gttaaaaaat aaccttattg
    74401 ttcgcctaca aagctgacaa agcgcgttcc tttatagctc agcgtacctt tatcgcccac
    74461 tgtcagggcg tggtactgct gggcgtcgag gcgaaacgtc tgctccattc ctccgctttg
    74521 cggtttgaag cttgcctcat agcgcatact ggtgcctgcc ggcgtcactt cctgctggcg
    74581 cgaacggcga tcgttaatcg gtttttcccg cttgttgctc accaccacca gcttttgctg
    74641 gagcggtgcc atatcattat cagctttttc ccgtcgttgt tgcataaaac gaaacgatgc
    74701 ggcgacgatg attaagccaa tgataacaat aaagaaaaga ggtggtttac tcatctttat
    74761 ccctcatcgg aaaatgcgga aataagcata ccctgccagt tatggtgttg tcatccgtcc
    74821 accctcgcca ctaaactgga agcaagaccg taggcattcc gcttacgaaa aaataacgaa
    74881 ttcaaggaac taagatgctt tggtcgttta tcgctgtctg tctttccgca tggctatctg
    74941 tggatgcatc gtatcgtggg ccaacctggc aacgctgggt gtttaaaccg ttaacccttc
    75001 ttctcctgct gttgctggcc tggcaagcgc cgatgttcga cgccattagc tatctggtgc
    75061 tggcggggct gtgtgcctca ctgctgggcg atgcgctaac cctgttgcca cgtcaacgtc
    75121 tgatgtacgc catcggcgcg tttttcctct cgcacctgct gtacaccatc tatttcgcca
    75181 gtcagatgac gctctctttc ttctggcctc tgccactggt gctgctggtt ctgggcgcgc
    75241 tgttactggc gattatctgg acgcgcctgg aagagtaccg ttggcctatc tgcacgttta
    75301 tcggcatgac gctggtgatg gtgtggctgg caggtgaact gtggttcttc cgtccgaccg
    75361 ctccggcgct ctctgcgttt gttggcgctt cgttgctgtt tatcagtaac tttgtctggc
    75421 tgggtagtca ctatcgccga cgcttccgtg cggataacgc gattgctgcg gcctgctact
    75481 ttgctggtca cttcctcatc gtccgctcgc tgtatctctg ataaaacttg actctggagt
    75541 cgactccaga gtgtatcctt cggttaatga gaaaaaactt aaccggagga tgccatgtcg
    75601 actcctgaca atcacggcaa gaaagcccct caatttgctg cgttcaaacc gctaactacg
    75661 gtacagaaca ccaacgactg ttgctgcgac ggcgcatgtt ccagcacgcc aactctctct
    75721 gaaaacgtct ccggcacccg ctatagctgg aaagtcagcg gtatggactg cgccgcctgt
    75781 gcgcgcaaag tggaaaatgc cgtgcgccag cttgcaggcg tgaatcaggt acaggtgttg
    75841 ttcgccaccg aaaaactggt ggtggatgcc gacaatgaca tccgggcaca agttgaatct
    75901 gcggtgcaaa aagcgggcta ttccctgcgc gatgaacagg cctccgacga accacaagaa
    75961 tcacgcctga aagagaatct gccgctgatt acgcttatcg tgatgatggc aatcagttgg
    76021 gggctggagc agttcaatca tccgtttggt caactggcgt ttatcgcgac cacgctggtt
    76081 gggctgtacc caattgctcg tcaggcatta cggctgatca aatctggcag ctacttcgcc
    76141 attgaaacct taatgagcgt agccgctact ggggcgctgt ttattggcgc aacggctgaa
    76201 gctgcgatgg tgttgctgct gtttttgatt ggtgaacgac tggaaggctg ggccgccagt
    76261 cgcgcgcgtc aaggggtcag cgcgttaatg gcgctgaagc cagaaaccgc cacgcgtctg
    76321 agtaacggtg agcgtgaaga ggtggcaata aacagcctgc ggcctggcga tgtgattgaa
    76381 gttgcggcag gtgggcgttt gcctgccgac ggtaaactgc tctcaccgtt tgccagtttt
    76441 gatgaaagtg ccctgaccgg cgaatccatt ccggtggagc gcgcgacggg cgataaagtt
    76501 cctgcaggcg ccaccagcgt agaccgtctg gtaacgctgg aagtgctgtc agaaccgggt
    76561 gccagcgcca ttgaccggat tctgaaactg attgaagaag ccgaagagcg ccgcgcacct
    76621 attgagcggt ttatcgaccg tttcagccgt atttacacgc cagcgattat ggcggtcgcc
    76681 ctgctggtaa cgctggtgcc gccgctgctg tttgccgcca gctggcagga gtggatttat
    76741 aaagggctga cgctgctgct gattggttgc ccgtgtgctt tagttatctc cacgcccgcg
    76801 gcgattacct ccgggctggc ggcagcagcg cgtcgtgggg cgttgattaa aggcggcgcg
    76861 gcgctggagc agctgggtcg tgttacccag gtggcgtttg ataaaaccgg tacgctgacc
    76921 gtcggtaaac cgcgcgttac cgcgattcat ccggcaacgg gtattagtga atctgaactg
    76981 ctgacactgg cggcggcggt cgagcaaggc gcgacgcatc cactggcaca ggccattgtg
    77041 cgcgaagcac aggttgctga actcgccatt cctaccgccc aatcacagcg ggcgctggtc
    77101 gggtctggca ttgaagcgca ggttaacggt gagcgcgtgt tgatatgcgc tgccggaaaa
    77161 catcctgctg atgcatttgc tggtttgatt aatgaactgg aaagcgccgg gcaaacggta
    77221 gtgctggtag tacgtaacga tgacgtgctg ggtgtcattg cgttgcagga taccctgcgc
    77281 gccgatgctg caactgctat cagtgaactg aacgcgctgg gcgtcaaagg ggtgatcctt
    77341 acaggcgata atccacgcgc agcagcggca atcgccgggg aactggggct ggaatttaaa
    77401 gcgggcctct tgccggaaga taaagtcaaa gcggtgaccg agctgaatca acatgcgccg
    77461 ctggcgatgg tcggtgatgg tattaacgac gcgccagcga tgaaagctgc cgccatcggg
    77521 attgcaatgg gtagcggcac agacgtggcg ctggaaaccg ccgatgcagc attaacccat
    77581 aaccacctgc gcggtctggt gcaaatgatt gaactggcac gcgccactca cgccaatatc
    77641 cgccagaaca tcactattgc gctggggctg aaaggcgttt tcctcgtcac gacgctgtta
    77701 gggatgaccg gactgtggct ggcagtgctg gcagataccg gtgcgacggt gctggtaacg
    77761 gcgaatgcgt taaggctgtt gcgcaggaaa taaggcaaac cgatcgcaac attgagcgcg
    77821 atcggtcccc tcgctcctct ggggagaggg ttagggtgag gggaaaaggc ggcatcgaag
    77881 ccaatcttcc cccatcaacc gcctttacga atcaaataac gataaggcag tccatccgtc
    77941 tctttagcaa ccagttcgtg ttccataaag gtacaaaacc caggaatatc gcgggtcgtc
    78001 gccggatcgt cagcaataat cagcaacgtt tcacctggct gcatattgcg cactgttttg
    78061 cgcaccatca ttactggttc cgggcagcgc aggccaagtg cgtcgagtgt gtggtcaggg
    78121 ctggaaaaga gatcggtcat tttcttctca tcacataaaa aaacggcgct agtttacgcc
    78181 ctgtgagtcc gtaagcaaac caggttaacg attgcgtgaa aattaaccat tgcattgtca
    78241 acgtaaagca gtatcatgcg gcggctcgaa aaaagggtca gcacgtataa aatagcgtgt
    78301 cgcacgtatt gggttccctc accccaatgg ttaatcaaaa aggtacaata tgaacgtttt
    78361 ctcgcaaacg caacgctata aggcgttgtt ctggttatcg ttatttcatc ttctggtgat
    78421 cacctccagt aactatctgg ttcagcttcc ggtctccatt tttggttttc ataccacctg
    78481 gggcgcgttt agctttccgt ttatctttct cgctactgac ctgaccgtgc gtatttttgg
    78541 cgcgccgctg gctcgtcgca tcatctttgc ggtaatgatc cccgcattgc tgatctccta
    78601 cgtcatctca tcgctgtttt atatggggtc atggcaagga ttcggcgcgc tcgcccactt
    78661 caacctgttt gtcgcccgta tcgccaccgc cagtttcatg gcctacgcgc tggggcagat
    78721 cctcgacgtg cacgttttta accgcctgcg tcagagtcgt cactggtggc tggcaccgac
    78781 agcgtccaca ctgttcggta acgtcagcga cacgctggcc ttcttcttca ttgccttctg
    78841 gcgtagcccg gatgccttta tggctgaaca ctggatggaa atcgcgctgg tcgattactg
    78901 tttcaaagtg ttaatcagta tcgttttctt cctgccaatg tatggcgtat tactcaatat
    78961 gctgttgaaa agactggcag ataaatccga aatcaacgct ttgcaggcga gttaaaggtt
    79021 cgttatcaga gttgtgataa gatggatgaa tgagccgtta tggccgttta tcgaaaggaa
    79081 gaagtcaatg cgcaatctgg ttaaatatgt cggaattggc ctgctggtta tggggcttgc
    79141 ggcctgtgat gataaagaca ctaacgctac ggcgcagggt tcggtcgcag aaagtaacgc
    79201 gaccgggaat cccgtcaacc tgcttgatgg caagttaagt ttctcgctgc cagcggatat
    79261 gaccgaccag agcggtaagc tgggaacgca ggccaataac atgcatgtct ggtccgacgc
    79321 caccgggcag aaagcagtca tcgtcatcat gggcgatgat ccgaaagaag atctggcggt
    79381 gctggcgaag cgtctggaag atcagcaacg tagccgcgat ccgcagctgc aagtggtaac
    79441 caataaagcc attgagctga aaggtcacaa aatgcagcag ttagacagca ttatctccgc
    79501 gaaaggccag acggcgtact cttccgttat tctgggtaac gtgggtaatc aactgctaac
    79561 catgcaaatt acgctgcccg ctgacaatca gcaaaaagca cagaccaccg cagaaaacat
    79621 cattaatacg ctggttattc agtaagtttt aagatgatga ggcggcctca ggtatttcca
    79681 ccgggggccg tttttttaat cgccacgtca gtaataacgc gattgcgacc agtcccgccg
    79741 ccgccagata aattaccgga acgcccgccc aactcatcac cagcccagcc agtggtccgg
    79801 tcacgccaag cgataaatcc ataaatacgg tgtaagttgc cagcgccgcc ccctgatttt
    79861 gctgcggaac cgcttttacc gccactacgc ccaatgcagg gaacaccagc gaaaaccccg
    79921 cccccgccag taagacgccg attttcgcca tccacggcat agtcgccacg ccaaccagta
    79981 gcaggccgat tatctcaacg ctaaagcaaa tcatcgccac gtttaagccg ccgatacggt
    80041 taatgccgtt agggaataac aaacgcgtac cgacaaacgc acagctaaac agcgtcagcg
    80101 cgaaagccgc accgtcccaa cctttagcgt cataaaacaa cgtgataaag gtggcgataa
    80161 cgccaaatcc ggcggaagcc agtgccagcg ccataccgta cagccagacg cgcccaagca
    80221 ccgcacgaaa cggcagcggt ttgcctttac tggcttttac cgtcggacgc gggatcgcca
    80281 acaaaatggc caccagtgcc acgcccataa tgattaacgc taacgcctgc aatccgcccc
    80341 agtgataaaa cacgacacct aacggcgcac ccatcgccat cgccccgtaa gtgacaatac
    80401 cgttccacga aatcacccgc ccgatatgta gcgaaccaac cacgccaaca ccccacaggg
    80461 tcgatcccgt tccggcaaaa ctttgtccaa tcccaaggat tacgcgcccc aggcacagta
    80521 ataacaggct gatgacgggc agactggcgg ttaatcctgc cgtcagatat cccagaccgc
    80581 tcataaagca gccgcataaa ccgaagacga caatcttttt gggtcccagc aaatcggcgt
    80641 aacgtccggc atgaggacgg ctcagcaagg tggcgaaata ttgcaggctg ataaccaacc
    80701 ctgcccagaa ggcactaaag cccatcacat catggacata gcctggtaat acagcgagcg
    80761 gcaacccgat ggtgaggtag ctggcgaagt taaacatgac aatggagaca atgcgcaaat
    80821 tcaggcgcaa tccgtttagc gcgggttcgg ctacgggttc gggcatgagg atcaccacat
    80881 ttttacaaca gtgtttcatt tttaccatgt gctgacgtga aaatcagcag taagaatcag
    80941 aatattgctg gcgtgactcc cgctacactt aatacaaaaa gtcacaagga agccccaatg
    81001 gaaacccctc aacccgataa aacgggcatg cgcattctgc tcaagttggc ctcgctggta
    81061 gtgatcctcg cgggcattca cgcagcggca gatatcattg tgcagctatt actggcgctg
    81121 ttttttgcca tcgttctcaa cccgctcgtc acctggttta ttcgtcgggg agtacaacgc
    81181 cccgttgcca ttacgattgt ggttgtggtg atgctgatcg cactcaccgc gctggtcggc
    81241 gtactggcgg catcgtttaa cgaatttatc tctatgctgc cgaagtttaa taaggagctg
    81301 acgcgcaaac tttttaaatt gcaggagatg ttgccttttc ttaatttgca tatgtcgccg
    81361 gagcgaatac tacagcggat ggactcggaa aaagtggtta ccttcaccac ggcgctaatg
    81421 accgggcttt ccggggcaat ggcgagcgtg cttttgctgg tgatgaccgt agtttttatg
    81481 ctgtttgaag tgcgccacgt cccttacaaa atgcgtttcg cgttgaataa tccacagatt
    81541 cacatcgccg gactacaccg cgcacttaaa ggcgtttcgc attatctggc gttaaagacg
    81601 ctactcagtt tatggacagg cgtaatcgtc tggctggggt tggagctgat gggggtgcag
    81661 tttgcgctga tgtgggcagt actggcgttt ttgctcaact acgtgcccaa tatcggtgcg
    81721 gtaatttccg ccgtaccgcc aatgattcag gtgctgctgt ttaatggtat ttacgaatgt
    81781 attctggtcg gcgcattgtt tttagtggtc catatggtca tcggcaatat tttagaacca
    81841 cggatgatgg gccatcgcct ggggatgtcc accatggtgg tatttctttc attgttaatt
    81901 tggggatggc tgctcggccc ggtagggatg ctactttcgg tgccattaac cagcgtgtgt
    81961 aaaatctgga tggaaaccac caaaggcggc agcaaactgg cgattttact ggggccaggc
    82021 agaccgaaaa gtcggttacc gggatgaggc gacaagtgtt acgatacgca ctttcatttt
    82081 ccattaaacg ttggccctga tatgtatcgg atagttctgg ggaaagtttc gaccttaagc
    82141 gcagctcctc tgccactggg tttacgcgag caagcaccgc aaggtccacg acgcgaacgc
    82201 tggctggcgg ggcgtgcatt gctttcgcac acgctttccc cgctaccgga gatcatctat
    82261 ggcgaacaag gcaaacctgc attcgcgccg gaaacgccgc tatggttcaa cttaagccat
    82321 agcggtgacg atatcgccct gctgttgagc gatgaaggcg aagtcggctg cgatatcgaa
    82381 gtgattcgcc cgcgcgccaa ctggcgctgg ctggcgaacg ccgtattcag cctcggggaa
    82441 catgccgaga tggacgccgt gcatcctgat cagcaactgg aaatgttctg gcgcatctgg
    82501 acgcgcaaag aagccatcgt taaacagcgt ggcggcagcg cctggcaaat cgtcagcgta
    82561 gacagcacct ataactcctc gctgtcagtc agccattgtc agctagaaaa tttaagcctg
    82621 gcgatctgca cccctacccc ctttacgctc accgccgaca gtgtgcaatg gatcgattca
    82681 gttaactgat ccgcccaccc gactgcccat ctattgatcc agaacaggta atcagtatga
    82741 cgaatactta aaatcgtcat acttatttcc gccatctatt ttaatccatt ggggttacca
    82801 tgttctctac actccgccgc actctatttg cgctgctggc ttgtgcgtct tttatcgtcc
    82861 atgccgctgc accagatgaa atcaccaccg cctggccggt gaatgtcggg ccactaaacc
    82921 cgcaccttta cacgcctaac caaatgttcg cccagagcat ggtttatgaa ccgctggtga
    82981 aatatcaggc agacggttcg gtgatcccgt ggctggcaaa aagctggacc cattcggaag
    83041 atggcaaaac ctggaccttc accttgcgtg atgacgtgaa attctccaac ggcgaaccgt
    83101 ttgatgcaga ggcggcggca gaaaacttcc gtgcagtgct cgataaccgt caacgtcacg
    83161 cctggctgga gctggcaaac cagattgttg atgtcaaagc actcagcaaa aacgagctgc
    83221 aaatcaccct gaaaagcgcc tactatcctt tcctgcaaga actggccctg ccgcgtcctt
    83281 tccgctttat tgccccgtca caatttaaaa atcacgaaac catgaacggg ataaaagcgc
    83341 cgattggcac cggaccgtgg gttttgcagg aatcgaaact gaatcagtac gatgtcttcg
    83401 tccgtaacga aaactactgg ggcgaaaaac cggcgattaa aaagatcacc tttaacgtga
    83461 tcccggaccc gactacccgc gcggtggcgt ttgaaactgg cgatatcgac ctgctgtacg
    83521 gaaacgaagg gttattaccg ctcgatacct tcgcccgctt tagccagaac ccggcttacc
    83581 acactcaact gtcacagccg atcgaaaccg tgatgctggc gctcaatacc gccaaagccc
    83641 ccaccaacga gctggcagta cgtgaagctc ttaattacgc ggtgaacaaa aaatcgctga
    83701 ttgataacgc gttgtatggt acccagcagg tcgccgacac cctgtttgcc ccttctgtgc
    83761 cctacgccaa cctcggcctg aaaccgcgcc agtacgatcc gcagaaagcg aaagcgttgc
    83821 tggaaaaagc cggttggacg ctgcctgctg gcaaagacat ccgcgagaaa aatggtcagc
    83881 cgctgcgcat tgaactgtcg ttcatcggca ccgatgcgtt aagcaaatcg atggcggaaa
    83941 tcattcaggc tgatatgcgc cagattggcg cagatgtctc gctgattggc gaagaagaga
    84001 gcagtatcta tgctcgtcag cgcgacggtc gttttggcat gattttccac cgcacctggg
    84061 gcgcgccata cgatccacac gccttcctga gttcaatgcg cgtaccgtcg cacgctgact
    84121 tccaggcaca gcaaggttta gccgacaagc cgctgattga taaagagatc ggcgaagtgc
    84181 tggcgaccca tgacgaaacg caacgtcagg cgctgtatcg cgacattctg acccgtctgc
    84241 atgacgaggc ggtttatctg cctatcagtt acatctcaat gatggtggtt tcaaaaccgg
    84301 aactgggtaa catcccctac gcgccgatcg ccaccgaaat cccgttcgaa cagattaaac
    84361 cggtgaaacc ttaatgttgc gttatgtatt acgccgcttt ctgctgctga tcccgatggt
    84421 gctcgccgcc tcggtgatca tttttttgat gctgcgcctc ggcaccggcg acccggcgct
    84481 tgattatttg cgtttatcta acctgccgcc gacgccggag atgctggcct ctacccgcac
    84541 tatgctgggg ctggatcagc cgctgtacgt ccagtatggc acctggctat ggaaggcgct
    84601 gcatcttgac tttggtatct cattcgccag ccaacgcccg gtgctggacg atatgctgaa
    84661 cttcctgccc gccacgctgg aactggcggg tgcggcgctg gtattaattc tgctcacctc
    84721 cgtgccgctc ggtatctggg cggcgcgcca ccgcgatcgc ttgcccgatt tcgccgtccg
    84781 tttcatcgcg tttctcggcg tgtcgatgcc taacttctgg ctggcgtttt tactggtgat
    84841 ggcgttttcg gtgtatctgc aatggctacc cgcgatgggt tacggcggct ggcagcacat
    84901 cattttgcct gcggtatcca tcgcctttat gtcgctggcg attaacgcgc gtttgctgcg
    84961 cgccagtatg ctggacgtcg ccggtcagcg tcatgtgacc tgggcgcggc tgcgcggcct
    85021 gaatgacaaa cagaccgaac gccgccatat tctgcgcaat gcctcgctgc cgatgatcac
    85081 tgccgtgggg atgcacattg gcgaactgat tggcgggacg atgattatcg aaaacatctt
    85141 tgcctggccg ggcgtcgggc gctatgcggt gtcggcgatt tttaaccgtg actatccggt
    85201 gatccagtgc tttacgctga tgatggtggt ggtttttgtg gtctgtaatt tgattgtcga
    85261 tttgctcaac gccgcgctgg acccgcgtat tcgtcgtcat gaaggagcgc acgcgtgaac
    85321 tttttcctct cctcccgctg gtcggttcgc ctggcgctga tcattatcgc cctgctggcg
    85381 ctgattgcgc tcaccagcca gtggtggctg ccgtatgacc ctcaggctat tgatttgccg
    85441 tcgcgcctgc tctcgccgga tgcgcagcac tggctgggca ccgatcattt agggcgcgat
    85501 attttctcgc ggctgatggc agcgacccgc gtgtcgctcg gctcggtaat ggcctgcctg
    85561 ctgttggtgc tgacattagg gctgattatt ggcggcagcg ccgggctgat tggcgggcgc
    85621 gttgatcagg ccaccatgcg cgtcgcggat atgtttatga ccttcccaac ctcgattctg
    85681 tcgttcttta tggtcggcgt gcttggcacc gggttgacca acgtaattat cgctatcgcc
    85741 ctttcgcact gggcatggta cgcgcgcatg gtgcgcagtc tggtgatttc actgcgccag
    85801 cgcgagtttg tgctggcatc acggctttct ggcgcgggcc atgtgcgggt gtttattgat
    85861 catctggcag gtgcggtgat cccctcgctg ctggtgctgg cgacgctgga tatcggtcat
    85921 atgatgctac acgtcgcggg gatgtccttc ctcggtctcg gcgtgaccgc gccgaccgcc
    85981 gaatggggcg tgatgattaa cgacgcgcgt cagtatatct ggacccagcc gctgcaaatg
    86041 ttctggccgg ggctggcgct gtttatcagc gtgatggcct ttaacctggt gggtgacgca
    86101 ctgcgcgatc atctggaccc tcatctggtg acggagcacg cacactaatg ccacaacaga
    86161 ttgaactccg taatatcgcg ctacaggccg cgcagccgct ggtgcacggc gtatcgttaa
    86221 ccctgcaacg tgggcgtgtg ctggcgttag tcggcggtag tggcagcggg aagtcgctga
    86281 cctgcgccgc gacgctgggc attctgcccg caggcgttcg ccagacggcg ggggaaattt
    86341 tggccgatgg aaaaccggtt tctccctgcg ccctgcgcgg catcaaaatt gccaccatca
    86401 tgcagaaccc gcgcagtgcc tttaatccgc tgcacaccat gcacacccac gcgcgtgaaa
    86461 cctgcctggc gctggggaaa cccgccgatg acgctacgct taccgctgcc atagaagcgg
    86521 tggggctgga aaacgccgcg cgcgtgctga agctctaccc gttcgagatg agcggcggca
    86581 tgttgcagcg catgatgatt gcgatggcgg tgctgtgcga atcaccgttt atcatcgccg
    86641 atgaaccaac caccgatctc gacgtggtag cacaagcacg catcctcgat ctactggaaa
    86701 gcattatgca aaaacaagca ccgggaatgc tgctggttac ccatgatatg ggcgtagtag
    86761 cgcgtctggc agacgatgtg gcggtaatgt ctcacggtaa aattgtcgaa cagggcgatg
    86821 tagaaacgct gtttaacgcc cccaaacatg cggtaacgcg cagcctggtt tccgcgcatc
    86881 tcgccctcta cggtatggag ctggcatcat gactttactt aacgtctccg acctttccca
    86941 tcactatgcg cacggtggat ttagcggaaa acatcagcac caggcggtgc tgaataacgt
    87001 ttccctggcc ctgaaaagcg gtgaaaccgt cgccctgctg ggacgcagcg gctgcggaaa
    87061 aagtaccctc gcgcggctgc tggtagggtt agagtcgccc tcacagggaa atattagctg
    87121 gcgcggcgaa ccgttggcga agctcaatcg cgcgcaacgt aaagcgttcc gccgtgatat
    87181 tcaaatggtg tttcaggact ccatcagcgc cgtgaatccg cgcaaaaccg tgcgcgagat
    87241 cctgcgtgaa ccgatgcgcc acctgctatc gctgaaaaaa gccgaacaac tggcgcgcac
    87301 cagcgaaatg ctgaaggcgg tcgatctcga cgacagcgtg ctcgacaaac gcccaccgca
    87361 gttaagcggc ggccagctcc agcgtgtctg tctggcacgc gcgctggcgg tcgaaccgaa
    87421 actgctgatt ctggatgaag ccgtttcgaa ccttgatctc gtgttacagg cgggcgtcat
    87481 tcgcctgctg aaaaagctgc aacaacagtt tggcaccgcc tgcctgttca tcacccacga
    87541 cttacgcctg gtggaacgct tctgtcagcg ggtgatggtg atggacaacg gacaaatcgt
    87601 cgaaacccag gtggtgggag ataaattaac cttttcctct gacgccggac gtgtgctaca
    87661 aaacgcggta ttacccgcat tccccgtgcg ccgtcgcacc acagaaaagg tttaacgcaa
    87721 atgcaacgag tcaccatcac gcttgatgac gatttactgg agacgctgga cagcctgagc
    87781 cagcgtcgtg gttataacaa ccgttccgag gcgatccgcg atattctgcg tagcgctctg
    87841 gcgcaggaag ccactcaaca acacggcaca caaggtttcg cggtgctgtc gtatgtgtat
    87901 gaacacgaaa aacgtgactt agccagccgt attgtctcca cccagcatca tcaccacgat
    87961 ctctcggttg ctactctgca tgtgcacatt aatcacgacg actgtctgga aatcgccgtg
    88021 ttgaaaggtg acatgggtga cgtacaacat tttgccgacg acgtcatcgc ccagcgcggc
    88081 gtgcggcacg ggcatttgca gtgcctgccg aaggaagatt aacacctccc aacgcgccgt
    88141 tatttcctga cggcgcagta gactcctgcc aaatatcgac tcacgtcaca tttttttgat
    88201 cacgatttgg tcccctaaaa tgtgagacgc ttcgatcctc tttttcgcct gttcacctac
    88261 tatacgcttg aagttgtcca tgattgtcca tagacaactg taaatgttca ggtgcgcgcc
    88321 atgaaatcat tgagtaagtc gtcacaaata ccgctctatc aacaagtggt ggagtggata
    88381 agagaaagta tttataccgg ggatctggtg gaagacgatc gcattccttc ggaataccag
    88441 attatggata tgctggaagt gagtcgggga accgttaaaa aagcggtcgc ccaactggta
    88501 aaagaaggcg tgttgattca ggttcagggg aagggaacat ttgtcaaaaa agagaacgtg
    88561 gcatatccgt taggtgaagg attattgtca ttcgcggaat cgctggaaag ccagaaaata
    88621 cattttacca ctgaagttat tacgtcacgg attgaaccgg ctaatcgtta tgtggcagag
    88681 aaattaagaa taacgcccgg tcaggatatt ctttaccttg agcgtttacg ttcaattggt
    88741 gatgaaaaag cgatgctgat agagaaccgt atcaatattg agctatgccc cggcatcgtg
    88801 gaaatcgatt ttaatcaaca caatttattt ccaacaatag aaagtttgtc gcaaagaaaa
    88861 attcgttact cggaaagtcg ctatgccgcg cgattaattg gtaatgaacg cggtcatttt
    88921 ttagatatca gtgaagatgc acccgttttg catctggagc agttagtctt tttctcccgc
    88981 ggattacccg ttgagtttgg caacgtctgg ttaaaaggaa ataaatacta tcttggcacc
    89041 gtgctgcaac ggcgggaagt gagttaagta cactttttta agaggaataa aatgcaaggc
    89101 atacagtttc aggaaaattt tattcaacga cttccggcag ggttaagcgt tgaacagatc
    89161 atccgtcagt tagcgcaacc gttggttacc gccgaactgg tggtccctga ttttgccgat
    89221 catgtactgg aacgtgaggc gacgtaccca acgggactgc ctaccgaacc accgtgtgtc
    89281 gccattccgc acacggacca taaacatgtc aggcacaatg caattgccgt cggcatcctg
    89341 ccggaaccgg tagtgtttgc cgatatgggc ggcgaccctg atcccgtacc tgtcagggtg
    89401 atttttttgc tcgccttagg cgaaagtaac aaacaattaa atgccctggg gtggattatg
    89461 gagatgattc aggatacgcc ctttatgtgc gccctgctta cgatggaaac aacagaaata
    89521 cacacagcaa tcttaaacaa aatgaaagaa cgaggtgaaa tatgagtcaa accattttat
    89581 ttgtctgcgc cacgggtatt gccacatcca cggcagtaac agaaaaagtc atggaatatt
    89641 gtaaagagca cggtcttaac gttaattatt ctcaaaccaa cgttgcctct ttacctggaa
    89701 ataccgacgg cgtagcactg gttgtttcaa cgactaaagt gccttatgaa ctcgacgtgc
    89761 cggtggttaa cggcttgcca attattactg gtattggcga agagaaagta ttggcgcaaa
    89821 ttgtttctat cctaaaaaag taattaataa taattaattt caacacacta catcaggcgc
    89881 taacgcgagg tgcgctctcg cctgaaaaag aggtttatta tgaacgatat cgcgcatacc
    89941 ctctataata ttgtgcaata tatattggga tttggtccca cggtaatgtt gccgttggtg
    90001 ttatttattc ttgctctctt tttcaaagta aaacccgcta aagccttacg ttcgtcatta
    90061 acggtcggca ttggttttgt cggtatttat gccattttcg atattcttac cagcaatgtc
    90121 gggccagcgg cccaggcgat ggttgaacgc accggaatta atttaccggt ggtggattta
    90181 ggctggccgc cgctttccgc tattacatgg ggttcgccaa ttgccccgtt tgttattccc
    90241 ctgactattc tgattaacgt ggcgatgctg gcgttaaata aaacccgcac cgttgacgta
    90301 gatatgtgga actactggca ttttgccctt gccggtacgc tggtttatta cagctccggc
    90361 agcctgttct ttggtttgct ggcggcggcg attgctgcgg tggtagtact taaactcgcc
    90421 gactggtctg cgccactggt acaaaaatac tttggcctgg aagggatctc tttgccgacg
    90481 ctctcttcgg tggtgttctt tccggtcggt ctgttggtcg acaaaatcat cgaccatatc
    90541 cccggcctca atcgtattca tatcgatccg gaaaccgtac agaaaaagtt tggcattttc
    90601 ggcgaaccga tgatggttgg cactattctg ggcatttttc tcggcgtaat tgccggatac
    90661 gatttcaaaa aagtattgct gcttggcatc agcattggcg gtgtgatgtt catcctgcca
    90721 cgcatggttc gcattctgat ggaaggttta ttaccgctgt ctgaagccat taaaaagtat
    90781 ctcaatgcca aataccctga ccgtgacgat ctctatatcg gcctggatat cgccgttgcc
    90841 gtaggtaatc cggcgattat ctccaccgcc ctgctgctaa cgccaatctc ggtctttatc
    90901 gcgtttgtcc tcccaggtaa tgaagtcctg ccgcttggcg accttgccaa cctggcggta
    90961 atggcgtcga tgattgcttt agccagccgt ggcaacattt tccgcaccgt tctggcggcg
    91021 atcccggtga ttattgccga cctgtggatt gctaccaaaa tcgcgccgtt tattaccgga
    91081 atggcgaaag acgttaactt caaatttgcc gaaggctcca gcggccaggt ttccagtttc
    91141 cttgatggcg gtaacccgtt ccgcttctgg ctgctggaaa tcttcaacgg caatctcatc
    91201 gccattgctc tggtgccggt tattgccctg gtgctgtatg gcattttccg aatgacgcgg
    91261 agcacggttt atgcctgata acagcgccgc tatcgttatc gatattggca ccaccaattg
    91321 caaagtcacc tgcttttcct gcctggacgc aacgacgttg ggcgcgcata aattcgtgac
    91381 ggcaaaacag atctccccac agggcgatgt cgatttcgat atcgacgccc tctggcagga
    91441 ggtccgccag gcgatagcgc aactgaacgc cgcttcaccg ctgcctgtca ggcggatcag
    91501 cattgccagt tttggcgagt caggggtgtt tcttgacgaa catggcgaga tcctgacgcc
    91561 aatgctggca tggtatgacc gtcgcggtga agagtatctg gcaacgctta gcgaggcaga
    91621 cagtgcggca ctttatgaca tttgcggatt accactgcac agcaattact ctgccttcaa
    91681 aatgcgttgg ttgctggagc attatccgct gcgcaatcgt cgcggcctgc gctggctaca
    91741 tgcaccggaa gtgctgctct ggcggctgac tggcgaacag cgaacggata tcaccttagc
    91801 cagccgtaca ctgtgtctgg acgtgcgcaa aggcgaatgg tcagcgaaag cgacggcgtt
    91861 gttacacgtt ccctgttcag catttgcgcc attggtgcag ccaggcgaac acgccggatg
    91921 ggtcagcgag tcgctctgca aaacgcttgg gttctcgcaa ccggtcagcg tgacgctggc
    91981 cggacatgac catatggtgg gtgcgcgggc gttgcagatg atgccgggcg atatccttaa
    92041 ctcgacgggc accacggaag gcattctgca actggataca caaccgacgc tggatgaaca
    92101 ggccaaacgt gacaagctgg caaacggctg ttactcgctt gccaaccagt tcaccctgtt
    92161 tgcttctctg cccgtgggcg gtttcgcgct ggagtggctg cgcaacacgt tccggctaac
    92221 tgatgaggag atcgccgcgt cgctcaatcg tgggtatgcg gattacctgg cggggaactg
    92281 gtcgcttgat gacattcccg tctttattcc gcatcttcgc ggttcgggtt caccctataa
    92341 aaatcgccac acccgcggat tattttatgg gcttggcgat acgttaaata tcgacatgtt
    92401 aatttccagc gtctcactgg gattaaccat ggaatttgcc aactgctttg cctgttttaa
    92461 tgtgcctggc accagcgtgt taaaagtgat cggtccggcg acccataacc ccctttggct
    92521 gcaattaaag gcagatattt tacagcgtcc ggttgaagca attgcattta gcgaggcggt
    92581 ttctgtcgga gccttattaa ccgcggcacc ggatattccg ccgccgcaag ttaccatagc
    92641 ccaacgtttg ttaccgaatc gggcaagata tcatcaatta cagcgttatc agcacaaatg
    92701 gaaaagctgg tatcagttga aattacagca agaaggcgtg atgccattac atcatcggga
    92761 ggagcactat gttgactaaa accgtggagg tcagaaacag tactggcctg catgcacgtc
    92821 cggcggcctg tctggcgaaa gccgccaaaa aatgtagctg taaagtgacg ctgcactatg
    92881 agggtaatga tattaatgcc accagtatga tgaatattat gcgcgccgga ataaaaggcg
    92941 gaaaaacggt ggaaatacgc tgcgacggtg atgatgaaaa cgaggccata cagactctca
    93001 ccgccttatt tcgcgaccgc ttcggtgaag ctgaataatt aactgatatt aaaaaatgag
    93061 gttttcaata tgccattagt gaatggacgg atactgctcg accgcattca ggaaaaacgg
    93121 gtattagcgg gcgcgtttaa taccaccaat ctggagacga caatttcaat tttaaacgct
    93181 attgagcgtt cgggattacc caacttcatt cagattgcgc ccaccaatgc acaactgtcg
    93241 ggatacgatt acatatatga aatcgtgaaa cgtcacgccg ataaaatgga tgttccggtc
    93301 agtcttcatc tggatcacgg gaaaacccag gaggatgtta aacaggcggt gcgcgcgggc
    93361 tttacctcgg tcatgattga cggtgccgca ttctcttttg aagagaatat cgctttcacc
    93421 caggaagctg tcgatttctg taaatcttat ggcgtgccgg ttgaagcgga gctgggggcg
    93481 attctcggca aagaagatga tcacgtcagc gaggccgatt gcaaaacgga accggaaaag
    93541 gtgaagacct ttgtcgaacg caccggttgc gacatgctgg cagtttctat tggtaacgtt
    93601 catggcctgg acgatatacc gcggatcgat atccccctgc tgaagcgcat tgccgaagtc
    93661 agcccggtgc cgctggttat ccacggcggc tccggtatcg ccccggagat attacgcagt
    93721 ttcgttaatt atcgcgtcgc taaa
//
LOCUS       DAPOXO010000006        87564 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPOXO010000006 DAPOXO010000000
VERSION     DAPOXO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 87564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87564
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.006"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(242..1642)
                     /gene="asnS"
                     /locus_tag="ROH59_000581"
     CDS             complement(242..1642)
                     /gene="asnS"
                     /locus_tag="ROH59_000581"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDX4803104.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPNTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
     gene            complement(1811..3013)
                     /gene="pncB"
                     /locus_tag="ROH59_000582"
     CDS             complement(1811..3013)
                     /gene="pncB"
                     /locus_tag="ROH59_000582"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDX4803105.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLENKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPLEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            3279..5891
                     /gene="pepN"
                     /locus_tag="ROH59_000583"
     CDS             3279..5891
                     /gene="pepN"
                     /locus_tag="ROH59_000583"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HDX4803106.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDVPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIVNEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     QDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            complement(5934..6701)
                     /gene="ssuB"
                     /locus_tag="ROH59_000584"
     CDS             complement(5934..6701)
                     /gene="ssuB"
                     /locus_tag="ROH59_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HDX4803107.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQDDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMQRGEFETRLRKQG"
     gene            complement(6698..7489)
                     /gene="ssuC"
                     /locus_tag="ROH59_000585"
     CDS             complement(6698..7489)
                     /gene="ssuC"
                     /locus_tag="ROH59_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HDX4803108.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVMAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRELVEMARS
                     YGLSGMPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            complement(7501..8646)
                     /gene="ssuD"
                     /locus_tag="ROH59_000586"
     CDS             complement(7501..8646)
                     /gene="ssuD"
                     /locus_tag="ROH59_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HDX4803109.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLLGETVDFNGKHIHVRGA
                     KLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPKLVKEKIEHVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQASFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVANDFIPRNVAQS"
     gene            complement(8643..9602)
                     /gene="ssuA"
                     /locus_tag="ROH59_000587"
     CDS             complement(8643..9602)
                     /gene="ssuA"
                     /locus_tag="ROH59_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415456.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein SsuA"
                     /protein_id="HDX4803110.1"
                     /translation="MRKIIKLVLAGLLSVSTIAVAAESSPEALRIGYQKGSIGMVLAK
                     SHQLLEKRYPQTKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLTTFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     LSAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            complement(9595..10170)
                     /gene="ssuE"
                     /locus_tag="ROH59_000588"
     CDS             complement(9595..10170)
                     /gene="ssuE"
                     /locus_tag="ROH59_000588"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HDX4803111.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFVP
                     EDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSTLKAQEILHGVFADDSQVIDYQHKPQFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNAHA"
     gene            10407..11417
                     /gene="pyrD"
                     /locus_tag="ROH59_000589"
     CDS             10407..11417
                     /gene="pyrD"
                     /locus_tag="ROH59_000589"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HDX4803112.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
                     KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQVMHHKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            11591..12133
                     /gene="zapC"
                     /locus_tag="ROH59_000590"
     CDS             11591..12133
                     /gene="zapC"
                     /locus_tag="ROH59_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415466.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HDX4803113.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     SPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWMPMPGDAAYVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(12130..13239)
                     /gene="ycbX"
                     /locus_tag="ROH59_000591"
     CDS             complement(12130..13239)
                     /gene="ycbX"
                     /locus_tag="ROH59_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HDX4803114.1"
                     /translation="MATLTRLFIHPVKSMRGIGLTHTLADVSGLAFDRIFMITEPDGT
                     FITARQFPLMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRALQQ
                     RCPASVKMEQFRPNLVVSGASAWEEDSWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPADEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAGA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSATGDDGTILCCSCVPKTALKLAR"
     gene            13337..15445
                     /gene="rlmKL"
                     /locus_tag="ROH59_000592"
     CDS             13337..15445
                     /gene="rlmKL"
                     /locus_tag="ROH59_000592"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HDX4803115.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETANIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYANRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            15457..17364
                     /locus_tag="ROH59_000593"
     CDS             15457..17364
                     /locus_tag="ROH59_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4803116.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVDGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKSEEAAAPKAETVKRSSSKLSYKL
                     QRELELLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            17494..18747
                     /gene="pqiA"
                     /locus_tag="ROH59_000594"
     CDS             17494..18747
                     /gene="pqiA"
                     /locus_tag="ROH59_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HDX4803117.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            18752..20392
                     /gene="pqiB"
                     /locus_tag="ROH59_000595"
     CDS             18752..20392
                     /gene="pqiB"
                     /locus_tag="ROH59_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HDX4803118.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     LLDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTSNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            20389..20952
                     /gene="pqiC"
                     /locus_tag="ROH59_000596"
     CDS             20389..20952
                     /gene="pqiC"
                     /locus_tag="ROH59_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309063.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HDX4803119.1"
                     /translation="MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQVAVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLARVWSQEAASIAQEIKRLP"
     gene            21208..21375
                     /gene="rmf"
                     /locus_tag="ROH59_000597"
     CDS             21208..21375
                     /gene="rmf"
                     /locus_tag="ROH59_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HDX4803120.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(21445..21963)
                     /gene="fabA"
                     /locus_tag="ROH59_000598"
     CDS             complement(21445..21963)
                     /gene="fabA"
                     /locus_tag="ROH59_000598"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HDX4803121.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAND
                     LKVGLFQDTSAF"
     gene            complement(22032..23792)
                     /locus_tag="ROH59_000599"
     CDS             complement(22032..23792)
                     /locus_tag="ROH59_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HDX4803122.1"
                     /translation="MTITKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIADAARTLQSDAGQLVGGHYEVSGHTIRLR
                     HAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVSQWCRWVTFTARHNHLPAPGADAWPVLIREAA
                     RYTGEQETLPLSPQWILRQCQEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            23978..24430
                     /gene="matP"
                     /locus_tag="ROH59_000600"
     CDS             23978..24430
                     /gene="matP"
                     /locus_tag="ROH59_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HDX4803123.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDEL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE"
     gene            complement(24506..25558)
                     /gene="ompA"
                     /locus_tag="ROH59_000601"
     CDS             complement(24506..25558)
                     /gene="ompA"
                     /locus_tag="ROH59_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706879.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HDX4803124.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     IPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTA
                     KLGYPITDDLDIYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEI
                     ATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKH
                     FTLKSDVLFTFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQA
                     LSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRV
                     EIEVKGIKDVVTQPQA"
     gene            complement(25914..26423)
                     /gene="sulA"
                     /locus_tag="ROH59_000602"
     CDS             complement(25914..26423)
                     /gene="sulA"
                     /locus_tag="ROH59_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HDX4803125.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTAEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            26642..27271
                     /gene="sxy"
                     /locus_tag="ROH59_000603"
     CDS             26642..27271
                     /gene="sxy"
                     /locus_tag="ROH59_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HDX4803126.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     CLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(27234..29396)
                     /gene="yccS"
                     /locus_tag="ROH59_000604"
     CDS             complement(27234..29396)
                     /gene="yccS"
                     /locus_tag="ROH59_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HDX4803127.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGQLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWKFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNQALAGLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(29406..29852)
                     /locus_tag="ROH59_000605"
     CDS             complement(29406..29852)
                     /locus_tag="ROH59_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDX4803128.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            29975..32029
                     /gene="helD"
                     /locus_tag="ROH59_000606"
     CDS             29975..32029
                     /gene="helD"
                     /locus_tag="ROH59_000606"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HDX4803129.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWRRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGMQQQIRQALSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIEGARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGDRCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDEGQLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(32061..32519)
                     /gene="mgsA"
                     /locus_tag="ROH59_000607"
     CDS             complement(32061..32519)
                     /gene="mgsA"
                     /locus_tag="ROH59_000607"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDX4803130.1"
                     /translation="MELTTRTLPSRKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(32615..33277)
                     /locus_tag="ROH59_000608"
     CDS             complement(32615..33277)
                     /locus_tag="ROH59_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HDX4803131.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
     gene            33450..33863
                     /locus_tag="ROH59_000609"
     CDS             33450..33863
                     /locus_tag="ROH59_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDX4803132.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQQGYGTLADVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(33908..34225)
                     /gene="hspQ"
                     /locus_tag="ROH59_000610"
     CDS             complement(33908..34225)
                     /gene="hspQ"
                     /locus_tag="ROH59_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HDX4803133.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(34283..35473)
                     /gene="rlmI"
                     /locus_tag="ROH59_000611"
     CDS             complement(34283..35473)
                     /gene="rlmI"
                     /locus_tag="ROH59_000611"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HDX4803134.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFTRRLQQAQKWRDWLAQKDGLDSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVA
                     VRKKEGMELTQGPITGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGV
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            35568..35846
                     /gene="yccX"
                     /locus_tag="ROH59_000612"
     CDS             35568..35846
                     /gene="yccX"
                     /locus_tag="ROH59_000612"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDX4803135.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKKLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR"
     gene            complement(35843..36172)
                     /gene="tusE"
                     /locus_tag="ROH59_000613"
     CDS             complement(35843..36172)
                     /gene="tusE"
                     /locus_tag="ROH59_000613"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HDX4803136.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGITLSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(36264..36923)
                     /gene="yccA"
                     /locus_tag="ROH59_000614"
     CDS             complement(36264..36923)
                     /gene="yccA"
                     /locus_tag="ROH59_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HDX4803137.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(37132..37219)
                     /locus_tag="ROH59_000615"
     tRNA            complement(37132..37219)
                     /locus_tag="ROH59_000615"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37183..37185),aa:Ser,seq:tga)
     gene            37647..38765
                     /gene="hyaA"
                     /locus_tag="ROH59_000616"
     CDS             37647..38765
                     /gene="hyaA"
                     /locus_tag="ROH59_000616"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HDX4803138.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIIAQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            38762..40555
                     /gene="hyaB"
                     /locus_tag="ROH59_000617"
     CDS             38762..40555
                     /gene="hyaB"
                     /locus_tag="ROH59_000617"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HDX4803139.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQLIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALKLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            40574..41281
                     /gene="hyaC"
                     /locus_tag="ROH59_000618"
     CDS             40574..41281
                     /gene="hyaC"
                     /locus_tag="ROH59_000618"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HDX4803140.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMIFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            41278..41865
                     /locus_tag="ROH59_000619"
     CDS             41278..41865
                     /locus_tag="ROH59_000619"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HDX4803141.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEDVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
                     QPANESRCLNYDCLSMENYEGIRLRQYRMTLEEQG"
     gene            41862..42260
                     /gene="hyaE"
                     /locus_tag="ROH59_000620"
     CDS             41862..42260
                     /gene="hyaE"
                     /locus_tag="ROH59_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HDX4803142.1"
                     /translation="MSNDTPFDALWQRMLARGWTPISESRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTCGN
                     YRGVLNGIHPWAELINLMRGLVEPQQERAS"
     gene            42257..43114
                     /locus_tag="ROH59_000621"
     CDS             42257..43114
                     /locus_tag="ROH59_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HDX4803143.1"
                     /translation="MSETFFHLLGPGTQLNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSERQPPLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQA
                     DGSESEIQEAIFCGLWRVRRRHGEQLLEDKLEAGCAPLALWQAATQNVLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     QWLAEGAPT"
     gene            43248..44792
                     /gene="appC"
                     /locus_tag="ROH59_000622"
     CDS             43248..44792
                     /gene="appC"
                     /locus_tag="ROH59_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HDX4803144.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFAIKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRELEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            44804..45940
                     /gene="appB"
                     /locus_tag="ROH59_000623"
     CDS             44804..45940
                     /gene="appB"
                     /locus_tag="ROH59_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDX4803145.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARNDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            45953..46045
                     /gene="cbdX"
                     /locus_tag="ROH59_000624"
     CDS             45953..46045
                     /gene="cbdX"
                     /locus_tag="ROH59_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HDX4803146.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            46125..47435
                     /gene="appA"
                     /locus_tag="ROH59_000625"
     CDS             46125..47435
                     /gene="appA"
                     /locus_tag="ROH59_000625"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001623747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acid phosphatase/4-phytase"
                     /protein_id="HDX4803147.1"
                     /translation="MKAILIPFLSLLIPLTPKSAFAQSEPELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKEGCPQP
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLNREKQDESCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIMTALAPHPPQKQVYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEVRIPACALHQDK"
     gene            complement(47423..47635)
                     /gene="cspH"
                     /locus_tag="ROH59_000626"
     CDS             complement(47423..47635)
                     /gene="cspH"
                     /locus_tag="ROH59_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HDX4803148.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            47921..48133
                     /gene="cspG"
                     /locus_tag="ROH59_000627"
     CDS             47921..48133
                     /gene="cspG"
                     /locus_tag="ROH59_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HDX4803149.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            48144..48332
                     /locus_tag="ROH59_000628"
     CDS             48144..48332
                     /locus_tag="ROH59_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDX4803150.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTDHAPLDFTK"
     gene            48307..48537
                     /gene="ymcE"
                     /locus_tag="ROH59_000629"
     CDS             48307..48537
                     /gene="ymcE"
                     /locus_tag="ROH59_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HDX4803151.1"
                     /translation="MRRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFGEM
                     AYNISYLTRVPGTNTLLACCCLLRPEEVNSEY"
     gene            48527..48700
                     /locus_tag="ROH59_000630"
     CDS             48527..48700
                     /locus_tag="ROH59_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HDX4803152.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(48749..49822)
                     /locus_tag="ROH59_000631"
     CDS             complement(48749..49822)
                     /locus_tag="ROH59_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDX4803153.1"
                     /translation="MAEKKRTRWQRRPGTTGGKLPWNDWRNATTWRKATQLLLLAINI
                     YIAITFWYWVRYYETAGSTTFVTRPGGIEGWLPIAGLMNLKYSLATGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQFVLPRWLDIPLRGVKYL
                     LLSFFLYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISMIVLLIASLFI
                     RHAWCRYLCPYGALMGVVSLLSPFKIRRNAESCIDCGKCAKSCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLAFSLQKPAANKKAFALSGWLMTLLVMGIMFAAIGYAMYAG
                     VWQSPVPEELYQRLIPQSPMIGH"
     gene            complement(49905..52637)
                     /gene="torS"
                     /locus_tag="ROH59_000632"
     CDS             complement(49905..52637)
                     /gene="torS"
                     /locus_tag="ROH59_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HDX4803154.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGQRLQLRQQQQQLSQQIVAAADEIARLAQGQAN
                     NAATSAGATQAGIYDLIEQHQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAPTLEKQLNNAVKILQRRQIRIEDPGVRTQVATTLTTVSQYSDLLALY
                     QQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGLVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIG
                     RLMDAFRSSVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATEIADDVPTALMGDPRRIRQVI
                     TNLLSNALRFTDEGHIILRSRIDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRVPLRVATAPVPKTVNQAVRLDGL
                     RLLLIEDNPLTQRITVEMLNSSGAQVVAVGNAAQALETLQNSEPFAAALVDFDLPDID
                     GITLARQLAQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQVNNDQPLDVSQLNEDAHLMGAEKIHEWLILFKQHALPLLDEIDIARASQDNEKIK
                     RAAHQLKSSCSSLGMRSASQQCAQLEQQPLSAPLPHEEITRSVAALEAWLIRKT"
     gene            52720..53748
                     /gene="torT"
                     /locus_tag="ROH59_000633"
     CDS             52720..53748
                     /gene="torT"
                     /locus_tag="ROH59_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HDX4803155.1"
                     /translation="MRVLLFLLLSLFMLSAFSADNLLRWHDAQHFTVQASTPLKAKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVANLPVIELVNAIDAPHVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVMTPKNADREHIRRSLSPGGFRPVYFY
                     QHTSAAKK"
     gene            complement(53721..54413)
                     /gene="torR"
                     /locus_tag="ROH59_000634"
     CDS             complement(53721..54413)
                     /gene="torR"
                     /locus_tag="ROH59_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HDX4803156.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            54543..55715
                     /gene="torC"
                     /locus_tag="ROH59_000635"
     CDS             54543..55715
                     /gene="torC"
                     /locus_tag="ROH59_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HDX4803157.1"
                     /translation="MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            55715..58261
                     /gene="torA"
                     /locus_tag="ROH59_000636"
     CDS             55715..58261
                     /gene="torA"
                     /locus_tag="ROH59_000636"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HDX4803158.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     EAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYEQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFISPQDASARGIRHGDV
                     VRVFNVRGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            58258..58857
                     /gene="torD"
                     /locus_tag="ROH59_000637"
     CDS             58258..58857
                     /gene="torD"
                     /locus_tag="ROH59_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HDX4803159.1"
                     /translation="MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLTAAVNGLENSIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLDLLSHLHFSLGEGTVPARRIDGLRQKTLTA
                     LREWLPEFAARCRQYDSFGFYAALSQLLLVLVECDYQKR"
     gene            complement(59112..59417)
                     /gene="cbpM"
                     /locus_tag="ROH59_000638"
     CDS             complement(59112..59417)
                     /gene="cbpM"
                     /locus_tag="ROH59_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HDX4803160.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPSEIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP"
     gene            complement(59417..60337)
                     /gene="cbpA"
                     /locus_tag="ROH59_000639"
     CDS             complement(59417..60337)
                     /gene="cbpA"
                     /locus_tag="ROH59_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HDX4803161.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIF
                     GQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVS
                     PWEAALGTKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
     gene            60872..62113
                     /gene="agp"
                     /locus_tag="ROH59_000640"
     CDS             60872..62113
                     /gene="agp"
                     /locus_tag="ROH59_000640"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HDX4803162.1"
                     /translation="MNKTLIAATVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYKLLEQIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTERTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDANGFCPMDKFDRVLNEAVK"
     gene            complement(62151..62378)
                     /locus_tag="ROH59_000641"
     CDS             complement(62151..62378)
                     /locus_tag="ROH59_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HDX4803163.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(62399..62995)
                     /gene="wrbA"
                     /locus_tag="ROH59_000642"
     CDS             complement(62399..62995)
                     /gene="wrbA"
                     /locus_tag="ROH59_000642"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDX4803164.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            63368..63541
                     /locus_tag="ROH59_000643"
     CDS             63368..63541
                     /locus_tag="ROH59_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDX4803165.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            complement(63624..64952)
                     /gene="rutG"
                     /locus_tag="ROH59_000644"
     CDS             complement(63624..64952)
                     /gene="rutG"
                     /locus_tag="ROH59_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HDX4803166.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKNVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGITTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNSVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQKP"
     gene            complement(64973..65467)
                     /gene="rutF"
                     /locus_tag="ROH59_000645"
     CDS             complement(64973..65467)
                     /gene="rutF"
                     /locus_tag="ROH59_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309280.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization flavin reductase protein
                     F"
                     /protein_id="HDX4803167.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEKALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALM
                     RPAC"
     gene            complement(65478..66068)
                     /locus_tag="ROH59_000646"
     CDS             complement(65478..66068)
                     /locus_tag="ROH59_000646"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HDX4803168.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWREPPVSDETLREIYALMKWGP
                     TSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFP
                     HGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFA
                     GSTLKSDLLINIGYGDSSKLFARLPRLSFEEACGLL"
     gene            complement(66078..66878)
                     /gene="rutD"
                     /locus_tag="ROH59_000647"
     CDS             complement(66078..66878)
                     /gene="rutD"
                     /locus_tag="ROH59_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HDX4803169.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLDQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYP
                     ASVTVLVSVNGWLRINTHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSS
                     ELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            complement(66886..67272)
                     /gene="rutC"
                     /locus_tag="ROH59_000648"
     CDS             complement(66886..67272)
                     /gene="rutC"
                     /locus_tag="ROH59_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein C"
                     /protein_id="HDX4803170.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            complement(67284..67976)
                     /gene="rutB"
                     /locus_tag="ROH59_000649"
     CDS             complement(67284..67976)
                     /gene="rutB"
                     /locus_tag="ROH59_000649"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HDX4803171.1"
                     /translation="MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFC
                     DALSSTSFARIA"
     gene            complement(67976..69067)
                     /gene="rutA"
                     /locus_tag="ROH59_000650"
     CDS             complement(67976..69067)
                     /gene="rutA"
                     /locus_tag="ROH59_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HDX4803172.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKS
                     DFKGDFFTMDDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVANVPGAEGVLLTFDDF
                     LSGIETFGERIQPLMQCRAHLPALTQEVA"
     gene            69355..69993
                     /gene="rutR"
                     /locus_tag="ROH59_000651"
     CDS             69355..69993
                     /gene="rutR"
                     /locus_tag="ROH59_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HDX4803173.1"
                     /translation="MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR"
     gene            complement(70033..73995)
                     /gene="putA"
                     /locus_tag="ROH59_000652"
     CDS             complement(70033..73995)
                     /gene="putA"
                     /locus_tag="ROH59_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HDX4803174.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQSLPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPR
                     EVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVIDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRQVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDNALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            74050..74259
                     /locus_tag="ROH59_000653"
     CDS             74050..74259
                     /locus_tag="ROH59_000653"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803175.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLINEIDMTGIKKITQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            74418..75926
                     /gene="putP"
                     /locus_tag="ROH59_000654"
     CDS             74418..75926
                     /gene="putP"
                     /locus_tag="ROH59_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HDX4803176.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNGHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKQASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQEG"
     gene            76146..76976
                     /locus_tag="ROH59_000655"
     CDS             76146..76976
                     /locus_tag="ROH59_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000497947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family protein"
                     /protein_id="HDX4803177.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFVLPPRAGATASRSV
                     "
     gene            77034..78161
                     /gene="efeO"
                     /locus_tag="ROH59_000656"
     CDS             77034..78161
                     /gene="efeO"
                     /locus_tag="ROH59_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HDX4803178.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAADIPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDKYADQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKY
                     RTKEGFENYDKLTDADRNALKGPITALAEDLAQLRGVLGLD"
     gene            78167..79438
                     /gene="efeB"
                     /locus_tag="ROH59_000657"
     CDS             78167..79438
                     /gene="efeB"
                     /locus_tag="ROH59_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HDX4803179.1"
                     /translation="MQYEDENGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNAKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYLGSALLRV"
     gene            80065..80853
                     /gene="phoH"
                     /locus_tag="ROH59_000658"
     CDS             80065..80853
                     /gene="phoH"
                     /locus_tag="ROH59_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HDX4803180.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMSGVEA
                     IGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVRSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS"
     gene            complement(80903..81316)
                     /gene="pgaD"
                     /locus_tag="ROH59_000659"
     CDS             complement(80903..81316)
                     /gene="pgaD"
                     /locus_tag="ROH59_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HDX4803181.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAIDLLTGY
                     FWQSEARSRLQFYFLLAVVNAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKTLVRV"
     gene            complement(81318..82643)
                     /gene="pgaC"
                     /locus_tag="ROH59_000660"
     CDS             complement(81318..82643)
                     /gene="pgaC"
                     /locus_tag="ROH59_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HDX4803182.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIIGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPRLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWNQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAAQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLVIENRYEHNLA
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            complement(82636..84654)
                     /gene="pgaB"
                     /locus_tag="ROH59_000661"
     CDS             complement(82636..84654)
                     /gene="pgaB"
                     /locus_tag="ROH59_000661"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HDX4803183.1"
                     /translation="MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVVISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDEMVS
                     REYFATWQQVREVARSRLVEVASHTWDSHYGIQANATGSLLPAYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKAEVNPHVFVWPYGEANGIAIAELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKPLQRVMHIDLDYVYDENRQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYRRLSPFDDRVRAQVGMLY
                     DDLAGHAAFDGILFHDDALLSDYEDASAAAIAAYQQAGFSGSLSEIRQNPEQFKQWTR
                     FKSRALADFTLELSARVKAIRGPHVKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYMEGVTEKSADQWLIQLTNQMKSIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDVIRPEFSTAWYPKND"
     gene            complement(84663..87086)
                     /gene="pgaA"
                     /locus_tag="ROH59_000662"
     CDS             complement(84663..87086)
                     /gene="pgaA"
                     /locus_tag="ROH59_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HDX4803184.1"
                     /translation="MYSSSRKRCPKTKWALKILTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALSWFAQKSTLSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALFKLKQLKS
                     GAPDKANLLAEAYIYKLTGRYQDELRAMTESLPENASKQQYPTEYVLALRNNQLAAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSENERYAIADRALAQYAALEILWHDNPDRTAQ
                     YQRIQVDHLGALLTRDRYRDVISHYQRLKKTGQIIPPWALYWVASAYLKDQQPKKAQS
                     IMTELFYNKETIATDLSDEELADLFYSHLESENYPGALTVTKHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEITTRELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLNDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERFFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRHEVSIE
                     GQERIWSSPYLIVDFLPNLYYEQNTEHDTPYYNPIKMFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
BASE COUNT        21505 a        22059 c        23035 g        20965 t
ORIGIN      
        1 cttctttcag acatccagaa tgccaaaaaa tcgtataaaa attgtgctat cagctaagaa
       61 aaaactaatc cgcaataaga atgcagatta ttttttgtgc gtaaatgttg cagtgtaata
      121 ttccgtaaca ggatgatcgt tatggcaggg ttgcaaatag attgcttgac ttaacaaaca
      181 gataacttga cagaaaggat aaaaaaagag ccagcgggcg ctggctcttg aagacactaa
      241 attagaagct ggcgttacgc ggagtacgtg ggaacggaat aacatcacgt acgttttgca
      301 cgccagttac gtaagcaatc aggcgttcaa aaccaagacc gaaacctgaa tgcggaacag
      361 taccgtagcg acgcagatcg cgataccacc agtaatcttc tttgttcagg cccatttcaa
      421 gcatacgctc gtccagcacg tccagacgtt cttcacgctg ggagccacca atgatctcac
      481 cgatgcccgg agccagaacg tccatagccg caacggtttt accgtcttcg ttaaggcgca
      541 tatagaacgc tttaatatct ttcggatagt ttttaaccac tactggtgct ttaaagtgtt
      601 cttccgccag ataacgctca tgctcagaag agagatcgac gccccagtaa accgggtttt
      661 caaacttcct gccgcagttt tcgagaatgg tcactgcgtc ggtgtaatcc acctgcgcga
      721 aatcggcctc aatgaagcgt tccagacgtg aaacggcatc tttatctacg cgttcagcga
      781 agaatttcat gtcgtcagcg cgttcttcga gaaccgcttt gaagacatat ttcagcatgg
      841 cttcagccag acctgcgata tcgttcaggt tagcaaacgc cacttccggc tccagcatcc
      901 agaattccgc caggtgacgg ctggtgttgg agttttcagc acggaaagtc gggccgaagg
      961 tataaatttt ggacaatgcg caagcgtagg tttcgccgtt caactggcca gatacggtca
     1021 ggaaagactc tttaccaaag aagtctttgt cgaaatccac tttgccctga tcgttacgcg
     1081 gcaggttttc cagatccagc gtagaaacac ggaacatttc gcctgcacct tcggtatcag
     1141 atgcggtaat cagtggcgtt gaaacccaga agaatccctg ctcgttaaag aagcgatgca
     1201 gcgcctgcgc cagcgtatgg cgaacgcgcg cgacggcacc aatcaggttt gtgcgcggac
     1261 gcaggtgagc gacttcacgc agatactcaa tgctgtggcg ttttgccgcc atcgggtaag
     1321 tgtttggatc ttcaacccaa ccagcaactt caaccttgct ggcctgaatt tcaaattgtt
     1381 gcccctggcc cggcgacgcc acgactttac ccgttacaat gaccgagcag ccggtggtca
     1441 gacgcaggac gtcttcattg taattgggca gagaattatt gatgacagcc tgtacaggat
     1501 caaagcagga accgtcataa acggcgagga aggagatgcc agcttttgaa tctcggcggg
     1561 tacgtaccca tccgcgcacg gtgacttcgc tgtcaacggc tacgcggccc tggagtacgt
     1621 cggctacagg cacaacgctc ataatattct ctctgttaat agtcggaaaa aataaacact
     1681 tgtccacccg taaatggggg gatacctatg ttacctggca tctgcaatca gacaagcaga
     1741 attcgcaaat gcagcgaaag atttcggaat taaaggtaaa aaaagggagc cgattagctc
     1801 cctgatgata ttaactggct tttttaatat gcggaaggtc gaacgctttg cgcagcgccc
     1861 gaacaaacgc tttatcgtgg cagatcgttt tgccagggct gtcagaaagt ttcgccaccg
     1921 gtttaccgtt acactctacc aacttaatga caatattcag aggttttacc tgggggatat
     1981 cgcaggtcag gcgagtccca ataccaaaac ttaattgcac gcgggaagag aagtggcggt
     2041 atagctcaac cgctttgcgt aaatccagat tgtcagagaa aaccagcgtt ttactctgtg
     2101 gatcaattcc cagcttttca taatgtgcaa tggctttttc accccattca agcgggtcgc
     2161 cagagtcatg gcgcaggccc tggtaacgac tggcaaattc cacgccgaaa tctcgcagga
     2221 aagcatccat ggtgatgcag tcggttaacg caatgccaag ttggtcggga tactcttcca
     2281 gccaggcagc aagtgcagct cgctggctgt tggctagatc cgggctgatt tgctgatgcg
     2341 cctggaacca ttcgtgtgcc tgtgttccca ttggcgtgag ggaaagccga cgcgccagat
     2401 cgtagttgct ggtgcccacg aaccaggatt cctgttgcag acgtttcacg atggtttctt
     2461 gtacttcgcg agaaaaacgg cggcgggtgc caaaatccat cagatggaag cgcgacatat
     2521 caagaccggc ggttaatgcc gagaagtcga ctaatttgtt ttccagcgtg tcgagggctt
     2581 gcgcaacgtc ggcctgcggt gagcgatagc gatgtaccat ttcactgata accgccagca
     2641 aaggaacttc ccagaggatg acttcacgcc acgggccgct taaacgaata tccagcttgc
     2701 cattatcgtt ggacacggtg acttgttccg ggttaaagcg gaactcgcgt agccagttaa
     2761 gatagtcggc cttaaagaaa ggcagggcag agagccactg atattcatca tcctgcaggc
     2821 gcaggtgctg catcgcctga acctgttcac gaatagcatc ggcataaata cccagcagat
     2881 cgtcacctcg gcaacgaaac tccgccgcga catgcacatc gtaatagtga tgaaacacgg
     2941 cttgctgcat atgcaactta taagcatctg tatccagcaa cgagtgcaga acaggagaag
     3001 cgaattgtgt cataggtgcg cagtagcgtc ctcgtacagg agcgtttagt acaataaaca
     3061 tcttcaggaa ctgctggagt ataccttgtt tcgcaattta ttgaaccccg atcacaccat
     3121 atgccacctt tctggtcgat ggcataacgc ggtgtatgtt ataaaaatgt agcaataaag
     3181 gcgtttgtac ctgaaaagat gaagattctg catagcgcga tttacgcaac aggaatagac
     3241 tgaacaccag actctataaa agatgctaaa ggttatttat gactcaacag ccacaagcca
     3301 aataccgtca cgattatcgt gcgccggatt accagattac tgatattgac ttgacctttg
     3361 acctggacgc gcaaaagacg gtcgttaccg cggtcagcca ggctgtccgt catggtgcat
     3421 cagatgttcc gcttcgtctc aacggcgaag acctcaaact ggtttctgtt catattaatg
     3481 atgagccgtg gaccgcctgg aaagaagaag agggcgcact ggtcatcagt aatttgccgg
     3541 agcgttttac gcttaagatc gttaatgaaa ttagcccggc ggcgaatact gcgctggaag
     3601 ggctttatca gtcaggcgat gcgctttgca cccagtgtga agccgaaggt ttccgccata
     3661 ttacgtatta tctcgaccgc ccggacgtgc tggcgcgttt taccaccaaa attattgccg
     3721 ataaaaccaa atatcccttc ctgctttcca acggtaaccg cgttgcgcaa ggtgaactgg
     3781 aaaatggacg tcattgggta cagtggcagg atccattccc gaaaccgtgt tacctgtttg
     3841 cgctggtggc tggtgatttt gatgtactgc gcgatacctt cactacccgc tctggtcgtg
     3901 aagtggcgct ggagttgtat gtcgatcgtg gcaaccttga tcgtgcgccg tgggcaatga
     3961 cctcgctgaa aaactccatg aaatgggatg aagaacgctt cggcctggag tatgacctcg
     4021 acatctatat gatcgtcgcg gtggatttct tcaatatggg cgcaatggag aataaggggc
     4081 tgaatatctt taactccaaa tatgtgctgg cccgcaccga caccgccacc gacaaagatt
     4141 acctcgatat tgaacgcgtt atcggccatg aatatttcca taactggacc ggcaaccgtg
     4201 tcacctgccg cgactggttc cagctcagtc tgaaagaagg tttaaccgtc ttccgcgatc
     4261 aggaattcag ctctgacctt ggttcccgcg cggtaaaccg tatcaataat gtgcgcacca
     4321 tgcgcggatt gcagtttgca gaagacgcca gcccgatggc gcacccaatt cgcccggata
     4381 tggtcattga aatgaacaac ttctacaccc tgaccgttta cgagaagggc gcggaagtga
     4441 ttcgtatgat ccacactctg cttggcgaag aaaatttcca gaaagggatg cagctctatt
     4501 tcgagcgtca tgatggtagc gcagcgacct gtgacgattt tgtgcaggcg atggaagatg
     4561 cgtcgaatgt cgatctctcc catttccgcc gttggtacag ccagtccggc acgccggttg
     4621 tgaccgtcaa agacgactac aatccggaaa ctgagcagta caccctgacc atcagccagc
     4681 gcacgccagc tacgccggat caggcagaaa aacaaccgct gcatattccg tttgccatcg
     4741 aactgtatga caacgaaggc aaagtgatcc cgttgcagaa aggcggtcat ccggtgaatt
     4801 ccgtgctgaa cgtcacccag gcggaacaga cctttgtttt tgataatgtc tacttccagc
     4861 cggtgcctgc gctgctgtgc gaattctctg cgccagtgaa actggaatat aagtggagcg
     4921 atcagcaact gaccttcctg atgcgtcatg cgcgtaatga tttctctcgc tgggacgcgg
     4981 cgcaaagttt gctggcaacc tacatcaagc tgaacgtcgc ccgtcatcag caagggcagc
     5041 cgttgtctct gccggtgcat gtggctgacg ctttccgcgc ggtgctgctc gatgagaaga
     5101 ttgatccggc gctggcggca gaaatcctga cgctgccttc cgtcaatgaa atggcagaac
     5161 tgttcgatat catcgatccg attgctattg ccgaagtacg cgaagcactc actcgtactc
     5221 tggcgactga actggcagat gagctgctgg ctatttacaa cgcgaattac cagagcgagt
     5281 accgtgttga gcatgaagat attgcaaaac gcactctgcg taatgcctgc ctgcgcttcc
     5341 tcgcttttgg tgaaacgcat ctggctgatg tgctggtgag caaacagttc cacgaagcga
     5401 acaatatgac cgatgcgctg gcggcgcttt ctgcggcggt tgctgcacaa ctgccatgcc
     5461 gtgacgcgct gatgcaggag tacgacgaca agtggcatca ggatggtctg gtgatggata
     5521 aatggtttat cctgcaagcc accagcccgg cggcgaatgt gctggagacg gtacgtggtc
     5581 tgttgcagca tcgctcattt accatgagca acccgaaccg cattcgttca ttgattggcg
     5641 catttgcggg cagcaacccg gcagcgttcc atgccgaaga tggcagcggt tatcagttcc
     5701 tggtggaaat gcttaccgac ctgaacagcc gaaatccaca agtggcttcg cgcctgattg
     5761 aaccgttgat tcgcctgaaa cgttacgatg ccaaacgtca ggagaaaatg cgcgcggcgc
     5821 tggaacagtt gaaagggctg gaaaatctct ctggcgatct gtacgagaag atcaccaaag
     5881 cactggcttg ataaataacc gaatggcggc aatagcgccg ccattcggag aatttacccc
     5941 tgttttctca ggcgagtttc aaattcacca cgctgcatca cccgctgcaa tacttccgct
     6001 tccagctctg ctaatcgtac cgaccctaac cggcgcggac gggggatatc caccgtcaaa
     6061 tccagaccaa tttttccctc ttcaattaac aacacccggt cagccatcgc caccgcttcg
     6121 ctcacatcat gcgtcaccag caagacggta aagccgtgct cctgccagag tgatacaatc
     6181 aaatcctgca tctcgagtcg cgttaaagcg tccagcgcac cgagtggttc atcaagcaac
     6241 aataaacctg gtcgatgaat cagcgccctt gccagcgcca cacgttgttt ctgcccgcca
     6301 gaaagtgcgg caggccattc ccccgcgcga ttctccagtc ctaccgcagc cagagcccga
     6361 cgcgcggcat cgcgccactg gcctttaagg cctaacccaa cgttatcaat caccgatttc
     6421 cacggcagca gacgcgcgtc ctgaaacatc attcgcgtat catcctgaat ctcagccagc
     6481 ggtgtggtgc ccgctaacac gtcgcctgcg gttggcgttt ccagacctgc cagcaggcgc
     6541 agcagggtac ttttgccacc accgctgcgg cccaccaccg ccacaaactg acctgctgga
     6601 atatgtaaat ccagttggtt caggacgata ttttccgcgt aatgtttgct tactgcattg
     6661 agcaacaatg gtgtgccctg gttcagacga gcagtattca taccgtggcc tccttcaaat
     6721 gataagccgg gttccagcgc aaccagagac gctctaacag ctgcgcgctg acgtcagcaa
     6781 gtttgccgag cagggcgtaa agaataatgg cgactaccac cacgtccgtt tgcagaaact
     6841 cccgcgcatt catcgccaga taaccaatgc cggaattggc agaaatagtt tcggcaacga
     6901 tcagcgtcag ccacatcagg cccaaagcaa aacgcacacc gaccataatt gagggcaggg
     6961 caccaggcag gatcacatgg ataaacagcg gcatgccgga taatccatag ctacgtgcca
     7021 tctccaccag ctcacggtcg atattacgga tgccatgcca ggtgttgata taaatgggga
     7081 atagcgtacc gagcgccacc agaaagattt ttgcggattc atcaatgcca aaccacaaaa
     7141 tcaccagcgg gatcagcgcc agatgcggca cgttgcgcaa catctgaatt gaggtatcca
     7201 gcagtcgctc accccagcgt gacagcccgc taatcagccc cagaattaat cccagcgatc
     7261 cgccaattga aaaaccaatc agtgcacgcc aggagctgat cgccagatgc tgccacagtt
     7321 cgccgctggc agagagcgtc cagaacgcca tcaccactcc ttccggtgag ggcaaaatac
     7381 gcgtcgatag ccagccaacc gaggaggcca gttgccacac cgccacgatg cccaccggta
     7441 aaaaccaggg ggcaacgcgc aataaccact tcttcactgg cgttgccatc atcgtgttcc
     7501 ttagctttgc gcgacgttac gggggataaa atcattcgcc accgcttcgc cttgtggatt
     7561 cagcggttgt ggctggggaa tttccgggat ggcgacatcc agatgtggga acagtaactc
     7621 gccgacccga tacgcttctt ccagatgcgg gtagcccgaa agcacaaaac tgtcgatgcc
     7681 aagtgcagcg tattcgttga ttcgcgcggc gaccgtagga ccatcgccca ccagcgctgt
     7741 cccggcaccg ccgcgcacta agccaacacc cgcccataaa ttggggctga tctccagatt
     7801 gtcgcgcttg ccgttatgta gcgccgccat tcgctgttgt cctacggaat ccgttcgggc
     7861 gaatgaggcc tgtgctttgg cgatagtttc atcatcaaga tgcgagatta accgctcggc
     7921 ggcctgccac gcttcgtcgt tggtttcacg aacaatcaca tgcagacgaa taccgaaacg
     7981 aattttgcgt ccatgcgcgg cagctttcgc ccgcacgtgt tcgattttct cttttaccag
     8041 tttcggtggt tcgccccagg taaggtagag atcaacttgt tctgccgcca gctcctgggc
     8101 gacatctgac gatccgccaa agtaaagcgg aggataaggc tgttgaatcg gcgggaagag
     8161 cagtttggcc ccgcgtacat gaatatgttt gccgttgaaa tccacagtct cgccaagcaa
     8221 caaccgccgc cagacctggg taaattctgc cgaggcttcg taacgctcgc tatgatcaag
     8281 gaacacgccg tcgcctgcca gttcttgggg atcgctgcct gtgaccaggt taaacaacgc
     8341 acgtccgtta gagagacggt caagcgtggc ggcctggcgg gcggcaacgg taggtgaggt
     8401 tacgctgggg cgcagggcga caagaaactt cagccgttgt gtcaccggga tcatcgacgc
     8461 cgccaccagc cacgcatctt cacacgatcg ccccgtcggg atcagcacac cggtatagcc
     8521 cagacgatcc gccgcttgcg caatttgttg cagataaccg tgatcaaccg gacgtgaacc
     8581 ttcttccgtt cccagataat gcccgtcacc gtgggtcggt aaaaaccaga acatattcag
     8641 actcataatt gttttccttc cagttgagtg ggctgccaga tgcgctggcg aatatcgact
     8701 tttttcggca ccagacggtt ttcataaaac agatctgccg tttgctgctg taaggcggca
     8761 acttcagcgc tcaacggttt gatggtggtg ggaggacgat gatccagata cgaggcaata
     8821 accggtgccg gtaagcccat cgtttttgcc agtaaagcga tgctttgttc gcgctggctg
     8881 cgggttaacg catcggcctc actaaaggtt gtcagcacac cctgaataaa agcgccgttt
     8941 ttttctgcat acggacgagc tgccagataa aacgatccag tttgattgag atcggtgccg
     9001 tctttcagca cccgcacgcc gccctgtaat aatgcagcgg agtagtaggg atcccagata
     9061 gcccaggcgt caacgttacc ttgctggaac gcggcgcggg catcggcagg cgtcaggtaa
     9121 gtgggctgaa tatccgtgaa tttaagcccg gcctggcgaa gggctcgcag taaaagattg
     9181 tgcgaactgg aacctttctg aaaggcaact ttgtgacctt taagatcggc tacggttttg
     9241 atcgggctgt tttctgccac cagaatcact tcggctttgg gcttcggtgg ctcgacgccc
     9301 acgtatacca aatcagcccc ggcagcctgg gcaaagattg gcggaatatc cccggtactg
     9361 ccgagatcga tactgccaac gtttaacgcc tccagcatct gtgggccagc ggggaactcg
     9421 acccaggaga tttttgtttg cggatagcgt ttttccagta actggtggct ttttgccagc
     9481 accataccaa tactgccttt ttgatagcct atacgtaacg cttcaggcga ggattctgca
     9541 gcaaccgcaa tcgtagagac gctaagtaaa cccgccagca ccagtttaat gatcttacgc
     9601 atgggcatta cctcgcaaag acagtaggtc aggaacctga acatcgcggc ggtgcaacgc
     9661 ctgccagaaa gtttctagcg cggtatcaag acgagtttgc agatttggcg tgaactgggg
     9721 tttgtgttgg taatcaatta cttgcgagtc atcggcaaac acgccgtgca ggatctcctg
     9781 ggctttcagc gtacttaaaa ctggcttaag ggcataatcg accgccagca gatgggccac
     9841 ggtgccgcct gtcgccagcg gcagcaccac tttgccttgc aacgcacgtt ctggcagcag
     9901 gtcgagcagg gttttcagtg caccggaata ggcggcttta tacacaggcg tggcgacaat
     9961 cagcccatcg gcctgttgca gctgttcggt gaaggtcttg agtgccggac tatcgaaacg
    10021 agcataaagc agatcttccg ggacgaagtt ttgcaaattc cagtgataaa cctctacatc
    10081 caggccattt agtttttccc gcgcatattc cagcaaggag ctggagcgag aaggaaatcg
    10141 aggactaccc gccagggtga tgacacgcat actctctcct tataaccaat tgttcttgtt
    10201 ttgttaacat tgataacaat tcggtcagtc tgacagaggg cgtccgcgag tcgaaatgat
    10261 ttatctgagg aagaaaagcc aaaaaaagca taaaaaaagc gcaataagaa aacgtttgct
    10321 atttattgcc gcaggtcaat tcccttttgg tccgaactcg cacataatac gcccccggtt
    10381 tgcacaccgg gaatccagga gagttcatgt actacccctt cgttcgtaaa gcccttttcc
    10441 agctcgatcc agagcgcgct catgagttta cttttcagca attacgccgt attacaggaa
    10501 cgccgtttga agcactggtg cggcagaaag tgcctgcgaa acctgttaac tgcatgggcc
    10561 tgacgtttaa aaatccgctt ggtctggcag ccggtcttga taaagacggg gagtgcattg
    10621 acgcgttagg cgcgatggga tttggatcca tcgagatcgg taccgtcacg ccacgtcccc
    10681 agccaggtaa tgacaagccg cgtctctttc gtctggtaga tgccgaaggt ttgatcaacc
    10741 gtatgggctt taataatctt ggcgttgata acctcgtaga gaacgtaaaa aaagcccatt
    10801 atgacggcgt tctgggtatt aacatcggca aaaataaaga tacgccggtg gagcagggta
    10861 aagatgacta tctgatttgt atggaaaaaa tctatgccta tgcgggatat atcgccatca
    10921 atatttcatc gccaaatacc ccaggattac gcacactgca atatggtgaa gcgctggatg
    10981 atctcttaac tgcgattaaa aataaacaaa atgatttgca agtgatgcac cataaatatg
    11041 tgccgatcgc agtgaagatc gcgccggatc tttctgaaga agaattgatc caggttgccg
    11101 atagtttagt tcgccataat attgatggcg ttattgcaac caataccaca ctcgatcgtt
    11161 ctctggttca gggaatgaaa aattgtgatc aaaccggtgg cttaagtggt cgtccgcttc
    11221 agttaaaaag caccgaaatt attcgccgct tgtcacagga attaaacgga cgcttgccga
    11281 ttattggtgt tggcggcatt gactcggtta tcgctgcgcg tgaaaagatt gctgcgggtg
    11341 cctcactggt gcaaatttat tctggtttta tttttaaagg tccgccgctg attaaagaaa
    11401 tcgttaccca tatctaatta tttcttcaaa ttcctcttta taagataatc agggctttat
    11461 tttcagccct ggttgtttta tattcatcgc tgttgcttat ttagacattt tgtactttta
    11521 ttgttgaggt tattaagcga agcgacaatg gattgtgtcg ctgcggtttt ataaggttgg
    11581 ggagtggcag atgcgaatta aaccagacga taactggcgt tggtattacg atgaagagca
    11641 cgatcgaatg atgctcgatt tagccaatgg tatgctattt cgctcacgtt ttgcgcgcaa
    11701 aatgttgact ccagatgcct tttctcccgc aggtttttgc gttgatgacg ccgcgctcta
    11761 tttctctttt gaagaaaagt gccgcgattt taatttatct aaagaacaaa aagccgaact
    11821 ggtgctgaat gcactggtag caattcgtta tctcaaaccg caaatgccga aaagctggca
    11881 ttttgtatct catggtgaaa tgtggatgcc catgccgggc gatgcggcct acgtttggtt
    11941 gagcgacact cacgagcaag tgaatttact ggtcgttgaa tctggcgaga atgccgcgct
    12001 atgtctactg gcacaaccct gcgttgttat tgcgggtcgc gcgatgcagt tgggcgacgc
    12061 cattaaaatc atgaacgaca ggctgaaacc gcaggttaat gttgacagct tcagcctcga
    12121 acaggcagtc taacgcgcca gcttaagcgc agtcttcggt acacaactac agcaaagaat
    12181 agtgccatca tcgcctgttg ctgatttttt tagcggcgtg acttcgcctt ctaaaagctg
    12241 aacacggcaa cttccacaaa tgcctgcgcg gcaagaataa gggatacgaa ttccctgatt
    12301 ttctaattgc tccagcagca cctgttggtt atttccacga aatgcctgtc cctgccagtc
    12361 aatatctacg tttgcgtccg gttgttgcgt gatgttggca gtatcatcag cggcacctgc
    12421 gccgtaaatt ttagctggag ccgttgccag aatttccacc tcatcgccaa cgcgaatcac
    12481 gccgctatta cgggcaatta aattctgacc aaaatcgaca tcgccgttat cctgggcagt
    12541 acggaaagat tgcagcgttt ttaatggttc gtctgccgga tgtttttgcc ctttttctgg
    12601 gctgacggtg gtgaaaatac agcggctaca aggcttaacc acatcaaaca cgacatcacc
    12661 aatgcgaatc actttccagc tatcttcttc ccaggccgat gcaccggaaa ccaccagatt
    12721 ggggcggaat tgctccattt ttacactggc cggacaacgt tgttggagag cacgtaacga
    12781 ggcctcgtta gcaagaaggt aaggatagcc atcagcaaat gacaggggta cagtgttgtg
    12841 gcgtttcacg cgccgggtca tttgtggccc cacccagcgt aattgcactt cgcgggagaa
    12901 aaatccactt agccatttgt tgatcgcatc tggcgcaatt cgcgcggtaa aatgtgtgcc
    12961 ccaaacttcg gttggtgcgt cttgtgtggc gaaatcagca aaacgaacat atgcgctact
    13021 gccatctggt gcggtgagat gcaagccatc atgcacgggt gaaggagtaa accgtaccat
    13081 tagcggaaac tggcgagcgg taataaacgt accgtcaggt tccgtgatca taaagatgcg
    13141 atcgaaggcc agaccactga catctgccag ggtatgtgta agaccaatgc cgcgcatcga
    13201 tttaacagga tgaataaaaa gccgggttaa tgtcgccacg gtgcggtcct caaatgaaaa
    13261 taagccctca actttatgac atgacgcgct tattagctat aatgcgcaac aattttctta
    13321 gagtaaaagt gacgatatga attctctgtt tgccagtacg gcccgtgggc tggaagagct
    13381 gttaaaaact gaactggaaa acctgggggc cgttgaatgc caggtggttc agggtggggt
    13441 ccatttcaag ggcgacacac ggcttgttta ccagagcctg atgtggagcc gcctggcctc
    13501 gcgtattatg ttgccgctgg gcgagtgtaa ggtttacagt gatttagacc tctatctcgg
    13561 cgttcaggcg atcaactgga cagagatgtt taatcctggc gcgaccttcg ctgtccattt
    13621 cagtggttta aatgacacca ttcgcaacag ccagtacggc gcgatgaaag tgaaagacgc
    13681 gatcgtcgat gctttcacgc ggaaaaatct gccacgtccc aatgttgatc gcgatgcgcc
    13741 ggatattcgc gttaacgtct ggctgcataa agaaaccgcc aatatcgccc ttgatctcag
    13801 tggtgatggc ttgcatctgc gtggctatcg tgatcgtgct ggtattgcac cgatcaaaga
    13861 aaccctggca gccgcgattg tgatgcgatc cggctggcag ccaggaacac cactgctcga
    13921 tccaatgtgt ggttctggta cgttgctgat tgaagcagcg atgctggcga ccgaccgcgc
    13981 accgggcttg caccgtggcc gttggggctt tagcggctgg gcgcagcatg atgaagctat
    14041 ctggcaggaa gtgaaagcgg aagcgcaaac tcgcgcccgt aaaggcctgg cagagtatag
    14101 ctctcatttt tacggttcgg acagcgacgc ccgggtgatt caacgtgcgc gcactaacgc
    14161 ccgtcttgcg gggattggtg aactgatcac ctttgaggtg aaagatgtcg cgcaactgac
    14221 caatccgctg ccgaaagggc cgtacggtac agtgttgagc aacccgccat acggtgaacg
    14281 tctggacagc gaaccggcgc tgattgcgct gcatagtctg ctgggccgaa tcatgaaaaa
    14341 ccagttcggt ggctggaatc tctctttgtt tagtgcctcg ccggatctgc taagctgcct
    14401 gcagctgcgt gcagacaaac agtacaaggc gaaaaacggc ccgctggact gcgtacagaa
    14461 aaactaccac gttgccgaaa gcacaccaga cagcaaaccg gcaatggtag cggaagacta
    14521 cgccaaccgc ctgcgtaaga acctcaaaaa attcgagaag tgggcacgtc aggaagggat
    14581 tgaatgttat cgcctgtatg atgccgatct gccggaatat aacgttgccg ttgaccgtta
    14641 tgccgactgg gtggtggtgc aggagtatgc gccgccaaaa actattgatg cgcacaaagc
    14701 gcgtcagcgt ctgttcgata ttatcgctgc aaccatttcg gtactgggga ttgcgccaaa
    14761 caaactggtg ctgaaaaccc gtgaacgcca gaagggcaaa aatcagtacc agaaactggg
    14821 cgagaagggc gagtttcttg aagttaccga atataacgct cacttgtggg tgaacttgac
    14881 ggattacctc gataccggtc tgttcctcga tcaccgtatc gcccgtcgta tgctcggtca
    14941 gatgagcaaa ggcaaagatt tcctcaacct gttctcctat accggtagcg ccaccgtgca
    15001 tgcgggatta ggcggcgcgc gcagcaccac caccgtggat atgtcgcgta cttatctgga
    15061 gtgggcagaa cgcaacctgc gtctgaatgg cctaaccggg cgtgcgcatc gcctgattca
    15121 ggccgattgc ctggcgtggc tgcgtgaggc aaatgaacag ttcgatctga tctttatcga
    15181 tccgccaacc ttctctaact caaaacgaat ggaagatgcg tttgatgttc agcgcgatca
    15241 tctggcgctg atgaaagatt tgaaacgtct gctgcgtgca ggtgggacga tcatgttctc
    15301 gaacaacaaa cgcggcttcc gtatggatct cgacggcctg gcgaaactgg gactgaaagc
    15361 acaagaaatt acgcaaaaaa cgctctccca ggatttcgcc cgtaaccgcc agatccacaa
    15421 ctgctggctg attaccgcag cctgaaagga atagtaatgt cattaatcag tatgcatggc
    15481 gcatggctgt cgttcagcga cgcgccgctt ctcgataacg cagaactgca tatcgaagat
    15541 aacgaacgtg tttgtctggt gggtcgtaac ggcgcaggca aatcgacgtt aatgaagatc
    15601 ctcaaccgtg aacaggggct ggatgacggt cgcattattt acgagcaaga tttgattgta
    15661 gctcgtctgc aacaggatcc gccgcgtaac gttgagggta gcgtttatga tttcgttgcc
    15721 gaaggcattg aagaacaagc ggaatacctg aaacgctatc acgatatttc gcgcctggtg
    15781 atgaacgacc cgagcgagaa aaatctcaac gaactggcga aggttcagga acagctggat
    15841 caccacaacc tgtggcagct ggaaaaccgc atcaacgaag tgctggcgca actgggatta
    15901 gatcctaatg ttgcgctgtc gtcgctttcc ggtggctggt tgcgtaaagc ggcattagga
    15961 cgcgcgctgg tgagcaatcc gcgcgtattg ctgctcgacg aaccgactaa ccacctggat
    16021 attgaaacca tcgactggct ggaagggttc ctcaaaacct tcaatgggac aattattttc
    16081 atttcccacg accgttcgtt tatccgcaat atggcgacgc gcattgttga tctcgatcgc
    16141 ggcaagctgg tgacctatcc agggaattac gaccagtacc tgctggaaaa agaagaagcc
    16201 ctgcgcgtgg aagaattaca aaatgccgag ttcgatcgca aactggcgca ggaagaggtg
    16261 tggatccgcc aggggatcaa agcacgtcgt acccgtaatg aaggccgcgt acgcgccctg
    16321 aaagcaatgc gtcgtgagcg tggtgaacgt cgcgaagtga tgggtaccgc aaagatgcag
    16381 gtggaagaag ccagccgctc cggtaagatc gttttcgaaa tggaggacgt ttgctaccag
    16441 gttgacggta agcaactggt gaaagatttt tctgcccagg ttctacgcgg cgacaaaatt
    16501 gccctgattg gtccgaatgg gtgcggcaaa accacgctgc tgaaactaat gctcggtcag
    16561 cttcaagcag acagcgggcg tattcacgtt ggcaccaaac tggaagtggc ttatttcgat
    16621 cagcaccgcg cggaactgga tcccgataaa acggtgatgg ataaccttgc cgaaggtaag
    16681 caagaggtga tggttaacgg caagccacgc cacgtattgg gctatttgca ggacttcctg
    16741 ttccatccaa aacgggcgat gacgccggta cgtgcgcttt ctggcggtga gcgtaaccgc
    16801 ttgttgttgg cgcgtttgtt cctcaaacca agcaacttat tgattcttga cgaaccgacc
    16861 aacgatcttg atgtcgaaac gctggaactg ctggaagaac tgatcgacag ctatcagggc
    16921 acggtattgc tggttagcca cgatcgtcag tttgtcgata acaccgttac agaatgctgg
    16981 atcttcgaag gcggcggtaa aattggtcgt tatgtcggcg gttatcatga tgcccgtggt
    17041 cagcaagaac agtatgtggc gctcaaacag cctgcggtga aaaaaagcga agaagccgcc
    17101 gcgccaaaag cagaaactgt aaaacgcagc agtagcaaac taagctataa attgcagcgt
    17161 gaactggagc tgctaccgca attgcttgaa gatctggagg cgaagctgga agctttacag
    17221 acgcaagtgg cggatgcttc cttcttcagt cagccgcatg agcagacgca aaaagtactc
    17281 gctgatatgg ctgctgcaga gcaggagctg gagcaagcct ttgaacgctg ggagtatctt
    17341 gaagcgttaa aaaatggtgg ctgatcgcaa aatagtcgat ttaaacagag actgctgaca
    17401 acggtaaaat tgcctgatgt actgggttta tcaggcatga aaaccaacac tttgttagtc
    17461 atctgcaaaa tagcgcatca ttaaggagta ccaatgtgcg aacatcatca tgccgcgaag
    17521 cacatcctgt gctcgcagtg tgacatgctg gtggcgttac cgcgccttga gcatggtcag
    17581 aaagcggcat gtccccggtg tggcacaacg ttaaccgtgg cgtgggatgc ccctcggcag
    17641 cgtcccaccg cctatgcgtt ggctgcactg ttcatgctgt tgctgtccaa cttgtttcct
    17701 tttgtgaata tgaacgttgc aggagttacc agtgaaatta cattactgga aattcccggc
    17761 gtgctttttt ctgaggacta cgccagcctc ggcacctttt tcctgttgtt tgtgcaactg
    17821 gttcccgcgt tttgtctgat aaccattctg ttactggtga atcgcgcgga attaccggtc
    17881 cgtttaaaag agcaactggc acgggtgctt tttcaactca aaacctgggg aatggcggag
    17941 attttcctcg cgggtgtgct ggtcagtttc gttaaactga tggcttacgg cagcattggg
    18001 gtaggcagca gctttctccc ctggtgttta ttttgtgtcc tgcaactgcg cgcttttcag
    18061 tgcgttgatc gtcgctggtt atgggacgac atcgccccga tgccagaact gcgccagccg
    18121 ctaaaaccag gcgtcacggg gatacgccag gggctgcgtt cgtgttcctg ttgtacggca
    18181 atccttcctg ctgatgaacc cgtgtgcccg cgttgtagta ccaaagggta cgttcggcgt
    18241 agaaacagcc tgcaatggac actcgcgctg cttgtaacgt ctatcatgct gtatcttccg
    18301 gctaatattt tgcccatcat ggtgacggat ttattaggct cgaagatgcc gtcgacgatt
    18361 ctcgctgggg tcattctgtt atggagcgaa ggctcttatc ccgtcgctgc ggtgattttt
    18421 ctggccagta ttatggtgcc aacgttaaag atgatcgcca ttgcgtggct gtgttgggat
    18481 gccaaaggac acggcaagcg cgacagtgaa agaatgcatt tgatttatga agttgttgag
    18541 tttgtaggcc gctggtcgat gattgacgtt ttcgttatcg cggtgctctc ggcgctggtg
    18601 cgtatgggag gtttaatgag tatttatccg gcaatgggtg cattaatgtt tgctttagtc
    18661 gtcataatga caatgttttc tgctatgacg tttgacccgc gtttgtcgtg ggatcgtcaa
    18721 cctgaatcag agcatgagga gtcctgacag tatggaatct aataatgggg aagccaaaat
    18781 ccagaaagtg aagaactggt ctcccgtgtg gatatttcct atcgtcacgg cgctcattgg
    18841 ggcctgggtt cttttttatc attacagcca tcagggaccg gaagtgaccc tgatcaccgc
    18901 gaatgcggaa ggaattgaag gtggcaaaac caccattaaa agccgtagcg ttgacgtcgg
    18961 cgtggttgaa agcgccacac tggctgatga tttgacgcac gttgaaatca aagcgcggct
    19021 gaattccggt atggaaaaat tgctgcataa agataccgtc ttttgggtgg tgaaaccgca
    19081 gattggtcga gaagggatta gcggcctggg aacgctgctg tctggggttt atatcgaact
    19141 gcagccaggc gcgaaaggca gcaaaatgga taaatacgat ttgctggact cgccaccgtt
    19201 ggccccgcct gatgcgaaag gtatccgtgt gcttctcgat agcaaaaaag ccgggcagct
    19261 ctcgccaggg gatccggtgc tgttccgtgg ctatcgggta ggttcggttg aaaccagcac
    19321 tttcgatacg caaaaacgca atatcagcta tcaactgttc atcaatgcac cttatgaccg
    19381 actggtgacc agcaatgttc gtttctggaa agatagtggc attgcggttg atctgacgtc
    19441 agcgggaatg cgtgtggaga tgggctcatt gacaacgctg cttagtggcg gtgtcagctt
    19501 tgatgtgccg gaaggtctgg atttagggca gccagtggca ccgaaaacag ctttcgtttt
    19561 gtatgatgat cagaagagca ttcaggattc gttgtacacc gatcacattg attatctgat
    19621 gttctttaaa gattcggtac gcggtctgca accgggagct ccggtagaat tccggggtat
    19681 tcgcctgggt accgtaagca aagtgccatt ctttgcgccg aatatgcgtc agacatttaa
    19741 cgatgattac cgtattccgg tactgattcg tatcgagcca gagcggctga aaatgcagct
    19801 tggcgaaaat gcggatgttg ttgagcacct tggcgaattg ttgaaacgtg gtttacgcgg
    19861 atcgctgaaa accggaaacc tggtcactgg cgcactgtat gttgatctcg atttctatcc
    19921 aaatacgcct gcaataaccg gtattcgtga atttaatggt tatcagatta tcccgaccgt
    19981 cagcggcggc ctggcgcaaa tccagcaacg actgatggaa gcgttggata agatcaacaa
    20041 actgccactg aatccgatga ttgaacaggc aaccagtacg ctttctgaaa gtcagcgcac
    20101 aatgaaaaac ctgcaaacga cgctggatag catgaacaag atcctcgcca gccagtcgat
    20161 gcagcagtta ccgacggata tgcagtcaac gttgcgtgaa ttgaatcgca gtatgcaggg
    20221 cttccagcct ggttccgcag cctacaacaa gatggtggcg gatatgcagc gccttgatca
    20281 ggtgttgcga gaactgcaac cggtgctgaa aacgctcaac gagaagagta acgcgctggt
    20341 atttgaagcg aaggacaaaa aagatccaga gccgaagagg gcgaaacaat gaaaaagtgg
    20401 ctagtgacga ttgcggcact gtggctggcc ggatgcagct ccggtgaaat taataaaaac
    20461 tattaccagt tacctgtggt gcagagcggt acacaaagca ccgccagcca gggtaatcgc
    20521 ctgttatggg ttgagcaggt cgctgttcct gactatctgg cggggaatgg tgtggtttat
    20581 caaaccagtg atgtgaagta tgtgattgcc aacaacaact tgtgggccag cccgttggat
    20641 caacagttgc gcaacaccct ggttgccaac ctgagtacgc aactgcccgg ctgggtggtt
    20701 gcctcccagc ctctgggaag cgcccaggac acgctcaatg ttaccgtcac ggagtttaac
    20761 ggtcgctatg atggcaaggt cattgtcagt ggtgagtggc tgttgaacca ccagggacaa
    20821 ctgatcaaac gtccgttccg tctggaagga gtgcaaactc aggatggtta cgatgagatg
    20881 gttaaagtgc tggcccgtgt ctggagtcag gaagccgctt ctattgcgca agagataaag
    20941 cgtctacctt aatcataaag atttgtaaat ataaccgtct ccggtatgtt gcctgaggcg
    21001 gtttttttgt ttctaacgtg cggaaaaagt tgttcctctt cacatttttt gtacaaccga
    21061 catgcccgtg tagctcacaa atatgacagt ggcgtgaatt ttgcgcattg acggcagtta
    21121 tgattcgcgg tattgcttaa ctgtggttgc atatttagta atcactgttt tcttttccac
    21181 cagaaaccag tatgagggaa acgaggcatg aagagacaaa aacgagatcg cctggaacgg
    21241 gcacatcaac gtggttatca ggccggcatc gccggacgct caaaagaaat gtgtccctat
    21301 cagacgctga atcaaaggtc acaatggctg ggaggctggc gagaagccat ggcggacagg
    21361 gtagtaatgg cctgattctg tctctttaaa aagaaacctc cgcattgcgg aggtttcgcc
    21421 tttttatact ctgtctgatt attatcagaa ggcagacgta tcctggaaca gaccgacttt
    21481 caggtcgttg gcggtataga tcaaacgacc atcaaccagc acttcgccat cagccaggcc
    21541 cataatcaga cgacggttaa ctatgcgttt aaagtgaata cgataggtca cttttttcgc
    21601 cgtcggcagc acctgacctg tgaatttcac ttcacctacg cccaacgcgc gacctttacc
    21661 ttcgccgccc agccagccga ggtagaaccc taccagctgc cacattgcgt ccaggcccag
    21721 gcatcccggc ataaccggat caccaatgaa gtggcatccg aagaaccaca gatccggatt
    21781 gatatccagc tctgcttcaa catacccttt gtcgaagtta ccacccgttt cggtcatttt
    21841 gaccacacgg tccatcatca gcatgtttgg tgctggcaat tgcgggcctt tagcgccaaa
    21901 cagttcaccg cgaccagagg caagaaggtc ttcttttgta taggattcgc gtttatctac
    21961 catgttctct gtaagcctta ttttattgaa gcacgcagga tagctaacac gtgtacgctg
    22021 aacaagtccg atcagttcgg aataaaccag ttcagccaac gtaatggcca tggaaaacgg
    22081 tgacgtcctt cctgttgcga tgcttgtgcg atacgttcct ggatggtttg catcagcgtc
    22141 gtctggcctt cgccatccca caccagattt aataataacg gcagtgcgtc agtcacatcg
    22201 tctactgccc agatggtgaa tttgccttct tctaccgctt tcaccagttc actgtgaaga
    22261 cttaaatggc gaacgttagc agtggggata atgacacctt gtttccccgt taactcacgt
    22321 tgctggcaaa tagcaaagaa gccttcgatt ttctcattta aaccaccgac tggctgggcg
    22381 cgaccgaact gatcgactga acctgtgata gcgatactct gattcaccgg cacatcggcg
    22441 agggcgctga tcagagcgca gagttcagcc atcgaggcac tatcgccatc cacttcactg
    22501 tatgactgct caaatgtcag cgatgctgag aaggggatct gttgctcaag ctgtagttcc
    22561 gacatcagga acgcttgcat gatcatcatc cctttcgcat ggatattgcc gccaagctcc
    22621 gctttgcgtt cgatgtcggt gaattcacca tcgccaatat gcacaacgca gctaatgcga
    22681 gaaggttcgc caaaagcgcg tggatgaccc ggaaattcaa tgaccgaaag ggcgttaatt
    22741 tgcccgatgc gttcgccttc ggtttcaatc aggatttgct cctgaaggat ctcatcctgc
    22801 atgcgttcag cgaggaaacc ttcgcgccat tcacgctgct gtagcattaa gtttagctgc
    22861 tcgccggaga aggtgtcgcc atcacacagg gaggcgacct cttgacactg gcggaggatc
    22921 cactgcgggc taagcggaag tgtttcttgt tcaccagtgt agcgtgctgc ttcgcggata
    22981 agtaccggcc aggcatccgc tcccggtgct ggtaagtgat tatgtctggc ggtaaatgtc
    23041 acccagcgac accactggct tactgactcc gcatcgacaa tctgcagagt atcttcaaat
    23101 tcgctataaa tagcctgctc tgaaagctct ggctccatct cctggaaatc agccaatgat
    23161 tcgcgttcgc ctaccagaat gactttcagc ttcaatggca tcgaaggcac agagacgggg
    23221 agagggcgcg actcatcaaa cgcaacccag tcaaaacgct cgcggttaac gatatttttc
    23281 agccgcatcc acagcagagg ttgcgccagc agtgtacgca aagagatgat gagaataccg
    23341 ccatttgcct gatgcaccag accaggctgc agggtaatat cgccattaaa ctgacgcagg
    23401 cagccaaaga gttgctctgc ttctacccag tcggcagcga caacttgcgt taaagtcgca
    23461 aaattatcat ctgcactcac tgcgtgacgt aagcggatgg tgtggccgga aacctcatag
    23521 tgaccgccca ccagttggcc tgcatcgctt tgtagcgtac gcgcggcatc agcaataaga
    23581 ttcagatact cagactcttc cggggccttc gccagcataa aagaggagga tgctcgcgta
    23641 tgcagcaact gctccagcgc aaattgcagt cgcggttgag tatcactgaa taaaggatcg
    23701 ttttcgtcaa tcaaatgtgg ctgagcaaat atttcctgat agctatcggt atcaggaacc
    23761 aggtcacgcc atgcaagttt cgtaatggtc aaagttgatg ttttttagtc tgttgtcaaa
    23821 gccgcgatta taccgtaacc ggcactgcag cacacgtaga aagcaacgac aatacgcctg
    23881 gcatgggcgt taaagctcac aggatggaga ttcttttctt cactggccta aaaagctgat
    23941 attctgtaaa gagttacacg gtaacattga gatcgctatg aaatatcaac aacttgaaaa
    24001 tcttgaaagc ggttggaaat ggaagtatct ggtgaagaag caccgcgaag gggagttaat
    24061 cacccgttac atagaagcca gtgccgccca ggaagccgtc gatgagttgc tctcgctgga
    24121 aaatgaaccc gtgctggtaa atggttggat tgacaagcat atgaatccgg aactggtcaa
    24181 tcgcatgaag cagaccattc gggccagacg gaagcgccat tttaatgcgg aacaccagca
    24241 tacgcgcaaa aaatcgatcg atctggaatt tatcgtctgg caacgtctgg ctggccttgc
    24301 gcagcgtcgc ggtaaaacgc tttctgaaac gattgttcag ctgattgaag atgcggaaaa
    24361 caaagagaaa tacgcgaata aaatgtcttc tttgaagcag gatctgcagg cattgctggg
    24421 taaggaataa ctgtcaaaag tcagttcaat ttacgcaagg cgaaaaaaaa ccccgcagca
    24481 gcggggtttt ttaccagacg agaacttaag cctgcggctg agttacaacg tctttgatgc
    24541 ctttaacttc gatctctacg cgacgatccg gagccaggca atcgatcagt gcagcacgct
    24601 gtttcacgtt gtcacaggtg ttgccagtaa ccgggttgga ttcgcccata ccacgtgcgg
    24661 agattttgtc tgccgggata cctttagaga tcaggtaatc aacaacggac tgagcacgac
    24721 gctcggacag agcctggtta taagcgtcag aaccgatgcg gtcagtgtaa cccagaacaa
    24781 ctacggaacc gtctttcgga tccaggttgc tcagctggct gtacagctga tccagagcag
    24841 cctgaccttc cggtttcagg gttgctttgt tgaaggtgaa cagaacgtca gacttcagag
    24901 tgaagtgctt ggtctgtact tccggtgccg gagctggagc cggagcaact actggagctg
    24961 cttcgccctg accgaaacgg taggaaacac ccaggctcag catgccgttg tccggacgag
    25021 tgccgatggt gtgtgcatca ccgatgttgt tggtccactg gtattccaga cgggtagcga
    25081 tttcgggagt gatcgcatac tcaacaccgc cagcgaagac cggagaaacg ccggtgtcgt
    25141 ggtctttaaa ggatgcgcca ccaggtacgt tagccttggt gtctgcacgc cataccatac
    25201 cacccagacg agtgtagatg tccagatcgt cagtgattgg gtaacccagt ttagcggtca
    25261 gctgaacgcc ctgagctttg tatgcgccgt tgatgttgtc gcctttgtac ggcatacgac
    25321 ctaaccagtc gtaacccatt tcaaagccaa catacgggtt aacctggtaa ccaccaaaag
    25381 cacctgcacc cagttggttt tcgtgggtcg gaccattgtt aggaataaaa ccagtgtcat
    25441 ggtactggga ccagcccagt ttagcaccag tgtaccaggt gttatctttc ggagcggcct
    25501 gcgctacggt agcgaaacca gccagtgcca ctgcaatcgc gatagctgtc tttttcattt
    25561 tttgcgcctc gttatcatcc aaaatacgcc atgaatatct ccaacgagat aacacggtta
    25621 aatccttcac cggggatctg ctcaatatta actctaccga tatcttcggc ttatgccgag
    25681 cacccctggc gatgtaaagt ctacaacgta gttgaaaact tacaagtgtg aactccgtca
    25741 ggcatatgaa aaaaaagtct tgtataaggt acgtttaatc ttttttgtca gcgacaattt
    25801 acagaagaaa atcgcggaaa ccgcttcaga caagcctccg caaggaaaat tagtcacgac
    25861 tgaaagcatt ggctgggcga taaaaaaagt tccaggatta atcctaaatt tacttaatga
    25921 tacaaattag agtgaatttt tagcccggaa agttgtctcg ttgcgtgaga ggatgcgctt
    25981 accggacgca taataaaccc catagcgtta ccttcatttg ccgcatcaac aagttcagca
    26041 tgctcttctg cagtcaaatc atctgccaac caaccgatca ccacgctgta attgcccgtg
    26101 cgtaaagcgc gaaccattga ctccacggtg tggcaagggg agagctggct aatctgcatt
    26161 actttcgtta agggtagccc agatgcctga acccattcgc gactcagttt ttgttgcggt
    26221 gttaaccaga gttgccagcg tgattgctga ccgagttgct gtaacaatgg caacagtaga
    26281 agttgcgtca tcatgggctg atcttcgcga tagacaactt cactgataag cccggctgta
    26341 gtgttttccg tagagacacg cgcaatttta cttgctgcgg atgagaacga cgaagaacga
    26401 tgtgcatagc ctgaagtgta cataatcaat ccagcccctg tgagttactg tatgaatgta
    26461 cagtacatcc agtgacgaca aagatcaacc ctattttcgg aaagagcctc gcaaattttg
    26521 tcgttggtgg cgggaaaaca taaattaatc ttgcccctta agaataagtt gcctattttc
    26581 gtagttaacg gatccgttaa tgtgaatcat tcttttatgt tatgatttta aaaggaattt
    26641 tatgaaaagc ctctcctata agcggatcta taaatcacaa gaatacctgg caacgttggg
    26701 cacaattgaa taccgatcat tgtttggtag ttacagcctg accgttgacg acacggtgtt
    26761 tgcgatggtt tctgatggtg agttgtatct tcgggcttgt gagcaaagtg cacagtactg
    26821 tgtaaaacat ccgcctgtct ggctgacata taaaaagtgt ggccgatccg ttaccctcaa
    26881 ttactatcga gttgatgaaa gtctatggcg aaatcaactg aagctggtgc gtctgtcgaa
    26941 atattctctc gatgcagcgc tgaaagagaa aagcacgcgc aatacccggg aaagactgaa
    27001 agatttgccc aatatgtctt ttcatctgga agcgattctc ggggaggtgg ggattaagga
    27061 tgtacgggcg ttacgtatac ttggggcaaa aatgtgttgg ttgcgactgc ggcagcaaaa
    27121 ctgtctggtg acagaaaaga ttctgtttat gcttgaaggg gccattatcg gcattcatga
    27181 agctgcgctc ccagtggcac gccgccagga gcttgcagaa tgggctgact ctcttacgcc
    27241 gaaacaggag tttcctgcgg aacttgagta atctggcgtt gcagacgacc aatctctggc
    27301 agtaatgcaa tcaataaccc aacttgttgt acgaccagag gttctttgct gtctgcccgt
    27361 ggttcaagtt gctgcatccg ctgtttcagg ccagctaatg cctgattgac gcgttcttca
    27421 tcagcaggtt gatgatgtag cgcgtcatca acatagcaaa cggcgtcatc aagaaacgcc
    27481 agaatttcag gattagttaa ctgctcccgg tgagcaccga gggctgagat atagctggta
    27541 aacgtatggt taaggcacag caaccgaaac gcggcttcgc gaatttgcgg ggtaacgttc
    27601 ggttcgctgg acatatttga taccaccgac gccagttcag catcacggtt gtgtgcatcg
    27661 cggcgggcaa tacgatacgc cagacggtta tcacgcccct gatggtattg ttccagtatg
    27721 gcatcgagat accggcagtt ggcctctgtg gcgcgttcga gcattcgcgg cagattgcga
    27781 aacttccagt caggccagat gtagctcact gccgcccacg caatggcaca accaatcagc
    27841 gtatcgatta cgcgaggtaa cgccacttca aaaccttcac ccagcaagtt gaaacacagt
    27901 agcaccaaaa gtgtgatgaa catcgttgca tgggcgtatt gcacgttacg gaaggcaaaa
    27961 aagagcacgc cggtaataac cagcagcacc agctgccctt ccaatgatgg cacaaaccac
    28021 agcacaggaa taccaattgc gatacctacc agcgtaccaa taatccttaa cttcaggcgg
    28081 tggcgcgtgg cgttatagtt tggctggcag acaaacaaac ttgtcagcaa gatccaatac
    28141 ccgtgatgca ttccggttat ctgaatgatg gcgtagccga agcacaacac cagcgacatt
    28201 cttaccgcat gacggaagag ggcggattcc ggcgtgaagt gacggctaag acgcagccag
    28261 atatcactca atccgtgcgg gctgtcatca gcgagctcat tttcgtcatt attatggggc
    28321 agtgcctggg cctgttctga ttcaattgtt gccagttggg catcaatggc acgtaaattg
    28381 ttcagtaaaa atcccagtgt tttgagtaaa tcagcaggcg cgccgttatc gcgcatccgc
    28441 tccagcgcag catcaatatg cgtaaaagcg cgctcaaaat gcggatcatg ttgataaggc
    28501 tgacgcagca aaatacagcg tgacagttgc tggcacgcct ggccctgcat cgacatcagc
    28561 cgctgaaaac ggaacagcac gtcgctgtgg cgaaaatgtt cacgcaatgt ttgatattga
    28621 atatgagaag agctggcacg ctcgtgaata tcctgcgcga caaagtaata atgcagtgtg
    28681 cgacgcgttc cccgttgacc acgatcgcca cgtaagcggg tcagcagcga gagtttcgtc
    28741 tgattcaatg tcgccatcag ctgaccgttg gcgagagcca aatcgtacag cggtgcctgg
    28801 ctttcatctt caatatcagg atcaaacatg cgcgacttga gctcaagata acgcgccagt
    28861 tgttcatagc aacgcgccag gttgtcctgc agcgggcgga ccgggaacag cagatgacca
    28921 ataagtgtca ggacgttgta ccagacggca ccggccagaa gatacatcgg ctgctgatac
    28981 cagtgctcat acagtgatgt tcccaacata gtgtaaatgg cgatcagcaa tgcaccgaag
    29041 gcaattgttg catagcgttg acccagaccg ccgagcaaaa tgaagccgct ggtagagagc
    29101 gttaagccaa tcgcaaatag ccagggccag ggaaacagca attctactga ggccgaggcg
    29161 ataaaaaagc agaacagcgt aatgatgagg ttacgcaaac gtcccgccag tcggtcatcg
    29221 agatcggtca gcgccgctgc caccatccca agcgtcagcg gaatcgtcag ttttacatca
    29281 cccagccacc acggaaacgc tgtggttcca caaagcgcaa taaaaatacg cgcgtaatac
    29341 agccaggcgc tgttccaggt atagcgtttg agcaaaggac ttagcataaa ggccatatta
    29401 gtggattatt caaaacgacg acgtgcattg gcttcgcgcg cagcttgcgc tgtttctacc
    29461 gataccacgc gacgaccgac cggccatagt gcaatagcgg caattttaaa gttcgcaata
    29521 ccgacaggaa tgccaatgat ggaaatacat tgtgcgatgc ccgttgcaat gtgcatcagg
    29581 cataaccacc agccaaagaa aatcagccag aaaatattca ataccgtacc gccagtattc
    29641 agcagcacat ttttgccagc cgggttcagt tcatcgacat gaatagcttc attgccataa
    29701 ggcaccagag acagtttagt gatctcccag caggatcgtg tcagtggtaa ggtaaaaatc
    29761 agcacaatac tgaccagagt cgccaacagc cagcccagag tggtggcaaa tccgccaagc
    29821 acaaagttca gaatgttcaa aacggtacgc ataaaacctc gctttactgt ggttttcagt
    29881 aatgggcggc aattgtaacg tttttttggg ctggagcacg ttttctctga cggttacact
    29941 gataagaaat aatttcgtgt ggatctacag agtcatggaa ctgaaagcga caacgcttgg
    30001 aaaacgtctg gcacagcacc cttacgatcg ggcggtgatc ctcaatgccg ggattaaagt
    30061 ctccggcgat cgccacgaat accttattcc tttcaatcaa ttactggcga ttcactgtaa
    30121 gcgcggtctg gtatggggcg aactggagtt tgtactgccg gacgaaaaag tggtgcgtct
    30181 gcacggcacc gaatggggcg agacgcagcg tttttaccat catcttgatg ctcactggcg
    30241 gcggtggagt ggcgagatga gcgaaattgc gtctggcgtt ttacgtcagc aactggattt
    30301 gattgccacg cgcaccggag aaaataaatg gctgacgcgt gagcaaacct ctggtatgca
    30361 gcaacaaatc cgccaggctt tgtcggcgtt accattgccg gttaaccgac tggaagaatt
    30421 cgataactgc cgtgaggcgt ggcgtaaatg tcaggcctgg ttgaaagaca ttgaaggcgc
    30481 tcggttgcag cataatcagg cgtataccga agccatgctt accgagtatg cggatttttt
    30541 ccgccaggtc gagtcttcac cgctgaatcc ggcgcaggcc cgggcagtcg ttaatggcga
    30601 gcattctttg ttagtgctgg ctggtgcagg aagcggaaaa acgtcggtgc tggtggcccg
    30661 tgcaggctgg ttgctggcgc gtggtgaagc gtcccctgag caaattttat tgctggcgtt
    30721 tggtcgcaaa gccgctgaag agatggacga gcgtattcga gaacgactac ataccgaaga
    30781 cattaccgca cgcacatttc atgcgctggc gctgcatatt attcagcagg gcagcaaaaa
    30841 agttccgata gtcagcaaac tggaaaatga taccgctgcc cgtcatgaac tttttattgc
    30901 tgagtggcgc aagcaatgca gcgaaaagaa agcgcaggcg aagggctggc ggcaatggct
    30961 gacggaagaa atgcagtggt cagtgccaga aggtaatttc tgggatgatg aaaaattaca
    31021 gcgtcgtctt gcctctcgcc tcgatcgctg ggtaagtctg atgcggatgc acggtggtgc
    31081 acaggcagaa atgattgcca gtgcacccga agagattcgc gatctgttca gtaaacgtat
    31141 caagttgatg gccccgttat taaaagcctg gaaaggtgcg ctgaaggcag aaaacgctgt
    31201 cgatttttcg ggccttattc accaggcgat tgtgattctg gagaaaggtc gctttatcag
    31261 cccgtggaag catattctgg ttgatgaatt tcaggatatc tcgccgcagc gtgcagcgtt
    31321 gttagcggca ttacgcaagc aaaatagtca aacgacgttg ttcgctgttg gtgatgactg
    31381 gcaggcgatt taccgattca gcggggcgca aatgtcgctc accacggctt tccatgaaaa
    31441 ctttggtgaa ggtgatcgct gtgatttaga cacgacctac cgttttaaca gtcgtatcgg
    31501 tgaggtggca aacaggttta ttcagcagaa cccaggccag cttaaaaagc cgctaaacag
    31561 cttaaccaat ggagacaaaa aagccgtcac attattggat gaggggcaac ttgacgcttt
    31621 gctggataag ctctctggtt atgccaaacc ggaagagcgc attctgatcc tggcgcgtta
    31681 ccatcacatg aggcctgcca gcctggaaaa agcggcaaca cgctggccga agttgcaaat
    31741 cgactttatg accattcatg ccagcaaagg gcaacaggcg gattacgtca tcatcgttgg
    31801 cttgcaggag gggagtgatg gttttccggc tgcggcgcgg gagtcgatta tggaagaggc
    31861 gctactgcca ccggttgagg atttcccgga cgctgaagaa cggcggttaa tgtacgtggc
    31921 gctgacccgg gcacgccatc gggtatgggc actgtttaac aaagagaatc cctctccttt
    31981 tgtcgaaata ctgaaaaatc tggatgtgcc ggtggcgaga aaaccgtaag aaacaggtgg
    32041 cgtttgccac ctgtgcaata ttacttcaga cggtccgcga gataacgctg ataatcgggg
    32101 atcagaatat cgaccgcgtc gttaaaatgc ggtgactgga taatgaagtc tgccgttgcc
    32161 acgttggtgg cgaccggaat gttccatacc gttgccagac gcagcaaggc tttcacgtca
    32221 ggatcgtgcg gcacggcatt tagtgggtcc cagaagaaaa tcaatacatc aattttccct
    32281 tctgagatca atgcgccaac ctgctggtca ccccccattg ggccactcaa catcgcgttg
    32341 acgttcatgc cggtcgcgcg ggaaattaag ttaccggtag tgcctgttgc atacagtacg
    32401 tgttgttcca gtaacggttg atgccgttcc acccagctca tcagcatttg tttgcagtga
    32461 tcgtgtgcca ccagcgcaat atgtttccgc gaaggtaaag tgcgagtcgt cagttccata
    32521 atgtacatcc gtagttaact ttcctacaga ttactgtaag tacttatcgc tgcaagataa
    32581 agactgaaaa agcctgcgca caggcacaaa aatctcagga ggatggttgt ttttccgccc
    32641 attgcaggaa agtatttcgc gtttgtgggt cagccagttt aaaccaatac ttcagccgtt
    32701 gttctgtgag cacctgagac tgcggtggaa tagcatccag ctcggaaaca cccgaaagca
    32761 gcgtactgtc atctgccatc atcgtggcaa attgcggtag tgaagcgcgt ttcgcggatt
    32821 tgttatagcg ttcaacctcg acctcataat caatcgtttt tgccgttgag gtaatggcga
    32881 gaatatccag ctttaccgga atcggcgtcg catcgccatc caacaattca aggcgcggcg
    32941 cggcatcaaa atggttagct tcccgctcat tctccaggcg aggcaggcga aaattgacct
    33001 ggttgatgag ctgggtatta aaactaacca ccagtggagg ggagatatag agccgttctt
    33061 cactattgga aagatgaatc gtcttctcaa cgcgaaacac taactgatgc ggtccattgt
    33121 ccagttcaat gctgtccgca ccgcgcagca gagagctgga aaccttctta ccgtcgagta
    33181 ccagaagatc gacatcagta gaaagccgca gcgtggtggc aaaaacggat accggcaaac
    33241 ataatgcaat caaggtggtc acgatgccgg ttttcataga tagctcctgt taaaagaccg
    33301 cccgaataat aatgtgtcaa aatttttctt taatcatact tactaacata tagacatatt
    33361 tcccgctttt gctctcattc attcgtatta gctgcatggt tggcatgtcg gctttgtcgt
    33421 acactttgtt aaacagtctg gaggaaataa tgaaagaaac cgatattgca ggcattttaa
    33481 cgtccactca caccattgcg ctggtggggg caagcgacaa acccgatcgt cccagctatc
    33541 gcgtgatgaa atatctactc gaccaggggt atcacgtcat tcctgtttcg ccaaaagttg
    33601 ccggcaaaac actgctgggc cagcaggggt atggcacgct ggcagacgtt ccggaaaaag
    33661 tcgatatggt cgatgttttc cgtaattcag aagcggcgtg gggcgtggcg caggaagcta
    33721 tcgccattgg cgcgaaaacc ctctggatgc aactgggggt gattaatgag caagcggcag
    33781 tactggcacg ggatgccggg ttaaatgtgg tgatggatcg ctgcccggct attgagatcc
    33841 ctcgcctggg cctggcaaaa taaaaaatac ccggaaggcg aaaaccttcc gggtatgttt
    33901 atgagaatta gttacgcaga cgcggcgcct ggagttgttt gcggatggtc tgcgccagct
    33961 catccatgga tggctgttca ggatgttcat cctgcaattc gctacttagc tgggcttcag
    34021 ccaggtaggt atgaaccggt aggccgttat catcctccat caccacgtga taccacggag
    34081 cggcgcgaag ctcgtcattc accgccagct catcaggcga cggttcagag agcgagtaaa
    34141 ccgggtcgat atccacgacc actccgagat aacctaacag ggaatggcgg acctgctggc
    34201 cgataccgaa tttgctggca atcatagtca cctcccggga aatctttacc tttgatataa
    34261 gggtaaaatt ccacatttca agttacatga cgcgacaggc aaaccctttc agatatagcc
    34321 cttccgggta ggtagcgatc accggatgat cggcggcctg acggaactgc tctataaatt
    34381 gtacatcacg accggcatca attgcggcat ccgcgatgat tttctgaaat aaatcgctgg
    34441 tcatcagacc ggaacaggag aaagtcagga gaacaccgcc ttcattcagc aactgaatcg
    34501 ccagcatgtt gatgtcttta tagccacggc acgcgcccat caactggctt ttattctcaa
    34561 caaacttcgg cgggtccatc acgataacat caaatttttc accgcgatcg cgataagtac
    34621 gcagcaattt aaagacatca tcacggacaa actctgcctt gctcagatcc agtttgttca
    34681 gctcaacgtt ctgccgtgca atatccagcg cttcctggga ggtatcaacg ctgacaacct
    34741 ggctgcaacc gcccatcaat gccgatacgg cgaaaccacc ggtataggag aaacagttaa
    34801 gtacgcgttt attttcgacg tagcggcggg tagccaggcg gctgtcacgc tggtccaggt
    34861 agtagcccgt tttgtgcccg tgctgaatat ccaccagcag tttcatgccg tgttcttcaa
    34921 tcggcagcag ggcaggcggc aactcgccgg tgatggggcc ctgagtcagc tccatccctt
    34981 cttttttacg taccgcgacg tcgctgcgat cgtaaatggc acattccggg tacaacgttt
    35041 gcagggcgct aattaatgcc gcgcgctgat actctgcgcc agcactcagc aattgcagca
    35101 ccagaaaatt accgaaacga tcgatagtaa tacccggcag gccatcagat tcaccggcga
    35161 ttaaacgata gctgtcgagg ccatcttttt gcgccagcca gtcacgccat ttttgtgctt
    35221 gctgcaaacg gcgggtaaaa aaagcaatgt cgatagactc agacgggtca aacgtccaga
    35281 cgcgcgcccg gatttgcgaa gctggcgaat aagcgccgcg tgctaaccat tttccctgat
    35341 gatcaacaat atcgatggtt tcaccgaggc tggctttacc ttccatgcgg gcaacggccc
    35401 cggaaaagac ccacggatgg cgacgaagta atgatttttc gcgccctttg gctaacacta
    35461 aacgtacact cataatttac ttttctgtcg atgcaaagaa atgggcgtca ttgtccggag
    35521 ttttccatgg atttgcaacg cgtccattaa ggataaggag agcagcaatg tcgaaagtct
    35581 gcataattgc ctgggtttac gggcgagttc agggcgtagg attccgctac accacgcagt
    35641 acgaagcgaa aaaactggga ctaaccgggt acgccaaaaa tcttgacgat ggcagcgtgg
    35701 aagtggttgc ctgcggtgaa gaagggcagg tggaaaaatt aatgcagtgg ttaaaaagtg
    35761 gcggcccgcg ttctgcgcgt gtggaacggg tgctcagcga gccgcatcat ccctccgggg
    35821 agttaacgga ttttcgtatc cgttaaatgc attttaccgg tttaggcagg ccagcaattt
    35881 tggtggcttg ctttgccgga cctttcggga acagtcggta cagatagcgg ctattgcctt
    35941 tctcttcgcc aaatttattc gccatcgctt ttaccagcat acgaatcgcc ggagaagtat
    36001 tgaattccag atagaaatca cgcacaaaac gcaccacttc ccagtgttct ggcgacagag
    36061 taatcccttc gttttctgca atcaccaccg ccagcggctc actccactgg ctgctttctt
    36121 tgagatagcc ttcggtatcc gtttctatct ctttaccttc gaagatcagc ataattcttt
    36181 actaccttaa tcagactggc ggcagtgtaa caaaaaacaa agccccgcat aaagcgaggc
    36241 tcggtaagta accctgggcg agattaatcg cggctggcga agcccagaat gctcagcagg
    36301 ctgacgaaga tgttgtacag cgaaacatac aggctaaccg tggcacgaat atagttcgtt
    36361 tcaccgccat gaatgatgtt gctggtttca aacaagatag cgccagagga gatcagaatg
    36421 aagaccgcgc tgatcgccag atgcagagca ggcagttgca ggaagatatt agcaaccata
    36481 ccaatcagca ccaccacaat acccgccatc agcataccgc cgaggaaaga catatctttg
    36541 cgggtggtca gcacatacgc agagcagcag aagaacacta acgccgttcc gcccagtgcc
    36601 atagcgatta cgtcacccat tccggcagac agataggtgt tcagaattgg tccgaggata
    36661 taacccagaa aaccggtaaa ggcgaatgcg gagataatcc cggtcggctt attcgccgtt
    36721 ttgtaggtca ggaacatcaa accatacata cccaccagcg tcagaatcag acccggagat
    36781 ggcagcatca gcaccgtact ggcagttgcg gtaatcgccg aaaaggccag cgtcaggctc
    36841 agcagaaaat aggtattacg cagcacctta tgggtgctaa gcagcgatgt acggtcatgt
    36901 gaagaactaa ctatacgatc cattgagtca ctctctatga cagatgtaat taattaagca
    36961 gcataatgat aatgcgtaag ggcacccaga agttttaccc atctttacgc atttgatctg
    37021 gaacaggttt aacagcggat tatcaggtca ttaggcagtg atataacgcc ctgagaattt
    37081 cgacaggcaa aagaaaaagg ggttagcatt tagctaaccc cttatcttat ttggcggaag
    37141 cgcagagatt cgaactctgg aaccctttcg ggtcgccggt tttcaagacc ggtgccttca
    37201 accgctcggc cacacttccg gaatgacgcg cactataaac atcccgatgc ggcgtgtaaa
    37261 cccctaattt gtttgtttgc ctgaaaaata gccaaaagtg cattgatagc gtgaaacaac
    37321 agcagattga tcatttcatc accatgaatt ccttctctat ttactcgttt agcaaccggc
    37381 taaacatccc caccacccgg caaaaagaaa aataggtcca tttttatcgc taaaagataa
    37441 atccacacag tttgtattgt tttgtgcaaa agtttcacta cgctttatta acaatacttt
    37501 ctggcgacgt gcgccagtgc agaaggatga gctttcgttt tcagcatctc acgtgaagcg
    37561 atggtttgcc ttgctacagg gacgtcgctt gccgaccatg tgcgcccggt gttctgccgg
    37621 tgtcgcaagg agaagagacg tgcgatatga ataacgagga aacattttac caggccatgc
    37681 ggcgtcaggg cgttacccgg cgcagctttc tcaaatattg tagtctggct gccacgtcgc
    37741 tgggattagg cgcgggaatg gcaccaaaga ttgcctgggc gctggagaat aaaccgcgca
    37801 ttccggtggt atggatccac ggcctggaat gcacctgctg taccgaatct tttatccgct
    37861 ccgctcaccc actggcgaag gacgtcatcc tttccctgat ttccctcgat tacgacgata
    37921 ctttgatggc tgccgccgga acccaggcgg aagaagtctt tgaagacatc atcgcgcaat
    37981 acaatggcaa atatatcctc gcagtagaag gtaatccgcc gctgggcgag caggggatgt
    38041 tctgtatcag cagcggacga ccgtttattg agaaactcaa gcgtgccgcc gctggagcca
    38101 gtgcgattat cgcctgggga acctgcgcgt cctggggctg cgttcaggcc gcgcgaccta
    38161 atccgacgca ggcaacgcct atcgacaaag tcatcaccga caaacccatt atcaaagtac
    38221 ctggctgccc gccgatcccg gatgtgatga gcgccatcat tacttacatg gtgacgtttg
    38281 atcgtctgcc ggatgtcgac agaatgggcc gtccactgat gttttatggt cagcgtatcc
    38341 acgataaatg ctatcgccgc gctcacttcg acgccggaga gttcgtccag agttgggatg
    38401 atgacgctgc ccgcaaaggt tactgcctgt acaaaatggg ctgcaaaggg cctaccacct
    38461 ataacgcctg ttcctccaca cgctggaacg atggcgtttc cttcccgatc cagtcaggtc
    38521 acggctgcct gggttgtgcg gaaaatggtt tctgggatcg cggttcgttc tacagccgcg
    38581 tggtcgatat tccacaaatg ggtacccatt ccaccgccga caccgtcggt ttaaccgcgc
    38641 ttggcgtggt ggcagcggct gttggtgtgc acgcagtcgc cagcgccgtt gaccagcgca
    38701 gacgtcataa ccagcaacct acagaaaccg aacatcagcc aggcaatgag gataaacagg
    38761 catgagcact cagtacgaaa ctcagggata caccatcaac aatgccggac gccgcctggt
    38821 ggtcgacccg attacgcgca ttgaaggcca catgcgctgc gaagtgaata ttaacgatca
    38881 gaatgtgatc accaatgccg tctcctgcgg caccatgttt cgcgggctgg agatcattct
    38941 gcaagggcgt gacccgcgcg atgcgtgggc gttcgttgaa cgtatctgcg gcgtctgtac
    39001 tggcgtacac gccctggctt cggtttacgc catcgaagat gccatcggta ttaaagtgcc
    39061 ggacaacgcc aatatcatcc gcaacattat gctggcaacg ctctggtgcc acgatcatct
    39121 ggtgcacttc tatcagcttg ccgggatgga ttggatcgat gtgttagatg cgctgaaagc
    39181 cgacccgcgg aaaacctccg aactggcgca aagcctctcc tcatggccga aatcatcccc
    39241 tggctatttc ttcgacgtac aaaaccgcct gaagaaattc gttgaaggcg gccagttggg
    39301 gatcttccgc aatggctact gggggcaccc gcagtacaaa ctgccgccag aagccaacct
    39361 gatgggcttt gcccactatc tcgaagctct cgatttccag cgtgaaattg tcaaaatcca
    39421 cgcggtcttt ggcggtaaaa acccgcatcc aaactggatt gtcggtggga tgccttgcgc
    39481 cattaacatt gacgaaagcg gcgcggtcgg ggcagtcaat atggaacgcc tgaacctggt
    39541 gcagttgatt atcacccgca cggcggattt cattaacaac gtgatgatcc ccgacgcctt
    39601 agccatcggt cagttcaaca aaccgtggag cgaaatcggc acggggcttt ctgataaatg
    39661 cgtcctcagt tacggcgcgt tccctgatat cgccaacgac tttggcgaga aaagtctgct
    39721 gatgcctggc ggcgcggtga ttaacggcga cttcaacaat gtactgccag tggatttagt
    39781 tgatccgcag caggtgcagg agtttgttga ccatgcctgg tatcgttatc ccaacgatca
    39841 ggttgggcgt catccgttcg atggcattac cgacccgtgg tacaaccccg gcgatgtcaa
    39901 aggcagcgat accaacattc agcagctgaa tgaacaggaa cgctactcgt ggatcaaagc
    39961 gccacgctgg cgcggtaacg cgatggaagt ggggccgctg gcacgcacgt taatcgctta
    40021 tcacaaaggc gatgctgcga ccgttgagtc ggtcgatcgt atgatgtcgg cgttgaaact
    40081 gccgctttcc ggcatccagt caacgttggg ccgcattttg tgtcgcgcgc acgaagcgca
    40141 gtgggccgca ggtaagttgc agtatttctt cgataaactg atgaccaacc tgaaaaacgg
    40201 caatcttgcc accgcttcca cggaaaaatg ggaaccagca acctggccga cagagtgccg
    40261 tggtgtcggt tttaccgaag cgccgcgcgg ggcgttaggc cactgggctg ccattcgcga
    40321 tggcaagatt gatctctatc agtgcgtggt gccgaccacc tggaacgcca gcccgcgcga
    40381 tcccaaaggg cagattggcg cttatgaagc ggcgctgatg aacaccaaaa tggcgatccc
    40441 cgagcaaccg ctggagatcc tgcgtactct gcacagcttt gacccgtgcc tcgcctgttc
    40501 aacacacgtg ctgggcgacg acggtagcga gcttatctcc gtgcaggtgc gttaacagcg
    40561 aaggagaatc atcatgcaac agaaaagcga caacgttgtc agtcactatg tctttgaagc
    40621 acccgtgcgg atatggcact ggctgacagt gttatgcatg gcggtgttga tggtcaccgg
    40681 ttactttatc ggcaagccgc taccttccgt cagcggcgag gcgacatatc tgttctatat
    40741 gggctacatc aggttaattc acttcagcgc cgggatgatt tttaccgtgg ttttgctgat
    40801 gcggatctac tgggcttttg ttggcaatcg ttactcccgc gagctgttta tcgtgccggt
    40861 atggcgtaaa agctggtggc agggcgtgtg gtatgaaatc cgctggtatc tgtttctggc
    40921 aaaacgtccg agtgccgata taggccataa ccccatcgcc caggcggcga tgttcggcta
    40981 tttcctgatg tcagttttta tgatcatcac cggctttgcg ctgtacagcg aacacagcca
    41041 gtacgctatt tttgcgccgt tccgttatgt ggtggaattt ttctactgga cgggcggcaa
    41101 ctcaatggac attcacagct ggcatcggct ggggatgtgg ctgattggcg catttgtgat
    41161 cggccatgtc tacatggcgc tgcgtgaaga catcatgtcc gacgacacgg tgatctccac
    41221 tatggtcaac ggctaccgta gccacaaatt tggcaaaata agtaacaagg agcgttcatg
    41281 agcgagcaac gcgtggtggt aatggggctg ggcaacctgc tgtgggccga tgaaggcttc
    41341 ggcgtgcggg tggcggaacg gctgtatgcc cattaccact ggcccgagga tgtggagatt
    41401 gtcgatggcg gcacccaagg actgaacttg ctggggtatg tcgaaagcgc cagtcatctg
    41461 ttgattctcg atgccattga ttacgggctg gaacccggaa cgctacgaac gtatgccgga
    41521 gaacgcattc cggcttatct cagcgcgaag aaaatgagcc tgcaccagaa cagtttctcc
    41581 gaagtgctgg cgctggcaga tatccgcgga catctgccag cacatattgc cctcgtcggt
    41641 ctgcaacccg caatgctcga cgactacggc ggcagcctga gcgaactggc gcgggagcaa
    41701 ctgcccgccg cggaacaggc ggcgctggcg cagctggctg cgtggggaat tgtgccgcaa
    41761 ccggctaatg aatcgcgctg tctcaattat gactgtctgt cgatggaaaa ttacgaaggc
    41821 attcgtttgc gccagtaccg gatgacactg gaggagcagg gatgagcaac gacacgccat
    41881 ttgatgcgtt gtggcaacga atgctggcgc gcggctggac gccgatcagt gaatcccgtc
    41941 ttgacgactg gcttacgcaa gcgccagacg gcgtggtgtt attaagcagc gatccgaaac
    42001 gcacgccaga ggtcagcgat aatccggtaa tgattggcga attattgcgc gagtttcccg
    42061 attatacatg gcaggtagcg attgctgacc ttgagcagag cgaagccatc ggcgatcgct
    42121 ttggcgtctt tcgctttccc gccacattag tatttacctg cggaaactat cgcggcgtgc
    42181 tgaatggtat tcacccgtgg gcggaactga taaacctgat gcgcggactt gtcgaaccgc
    42241 agcaggagcg tgcctcatga gcgaaacttt tttccatctg ctggggccag gaacgcaact
    42301 gaacgatgac agtttcagca tgaatccact gccgatcacc tgtcaggtga atgatgaacc
    42361 gagtatggcg gccctggagc aatgtgctca cagcccgcag gtgattgcgc tgttaaacga
    42421 gttacaacat caactaagcg aacgccagcc gccgttgggc gaggtactgg cagtcgatct
    42481 gttaaatctc aacgccgacg atcgtcactt tatcaatacg cttctcgggg aaggggaagt
    42541 gtcagtgcgc attcagcagg ctgatggtag tgaaagtgaa attcaggagg cgatcttctg
    42601 cggattatgg cgggtacgca gacgtcacgg cgaacagttg ctggaagaca aactggaggc
    42661 tggctgcgca ccgctggcgt tgtggcaggc ggcaacgcaa aacgtcttgc cgacagattc
    42721 gctgttaccg ccgcccattg atggcctgat gaatggccta ccgttggccc atgaattact
    42781 ggcacatgta cgtaaccccg acgcacagcc gcacagcatt aatctgacgc aattacccat
    42841 cagcgaagct gaccggcttt ttctctcacg tctctgtggg ccgggaaata ttcagattcg
    42901 taccattggc tatggcgaga gctatatcaa cgccacgggg ttacgccatg tctggcattt
    42961 acgctgtacg gacaccttaa aaggcccgtt actggaaagt tatgaaatct gcccaatacc
    43021 ggaagtggtg ctggcagcgc cagaagattt ggtcgactct gcgcagcggc ttagcgaggt
    43081 atgccagtgg ctggcggaag gtgcaccgac gtaaaaagac ggtaagtatc gctttcaggc
    43141 ttatgaatat cgcaatcggc gaatacctct ggtcgtagag tttcaggata aagagggaga
    43201 tctaccatta acgggttatt tttctctctt cgcctacagg agtgcgcatg tgggatgtca
    43261 ttgatttatc gcgctggcag tttgctctga ccgcgctgta tcacttttta tttgtacccc
    43321 ttaccctggg gctgattttt ttgctggcta tcatggaaac catttacgtg gtcaccggca
    43381 aaacaatcta ccgcgatatg acgcgcttct ggggtaagct cttcggtatc aactttgctc
    43441 ttggcgtggc taccggcctg acgatggagt ttcagtttgg tactaactgg tcattctatt
    43501 ccaactatgt gggcgatatt tttggcgcac cactggcgat ggaagcatta atggccttct
    43561 tcctcgaatc cacctttgtc gggctgttct tcttcggctg gcaacggctg aataaatacc
    43621 agcacctgct ggtgacgtgg ctggtggcgt tcggttcaaa tctctctgcg ttgtggatat
    43681 tgaatgccaa cggttggatg caatacccga ctggtgcgca ttttgatatc gacaccctgc
    43741 gtatggagat gaccagtttc agcgagctgg tctttaaccc ggtcagccag gtgaaatttg
    43801 tgcacaccgt aatggcggga tacgtgaccg gggctatgtt tattatggcg atcagcgcct
    43861 ggtatttact gcgcggacgg gagcgcgatg tcgcattacg ctcgtttgcc atcggttccg
    43921 tcttcggtac tctggcgatt atcggtacgc tgcaactcgg agacagttct gcgtatgaag
    43981 tcgcgcaagt acaaccggta aaactggcgg cgatggaagg ggagtggcaa acagaacctg
    44041 cacctgcacc gttccatgtg gttgcctggc cggaacagga tcaagagcgt aacgcctttg
    44101 ccatcaaaat tcccgcgctg ctagggatcc tcgccactca ctcattagat aaacccgtgc
    44161 cgggtctgaa gaatttgatg gctgaaacct accctcgctt gcaacgtgga cgtatggcct
    44221 ggctgttaat gcaggaaata tcgcaaggca atcgtgagcc gcatgtgttg caggcattcc
    44281 gggagctgga aggcgacctg ggttacggca tgttgctctc ccgctatgcg ccggatatga
    44341 atcatgtcac agccgcacag taccaggcgg cgatgcgtgg cgcgatacct caggttgcgc
    44401 cggtattctg gagtttccgc atcatggtgg gctgtggttc cctgctgcta ctggtgatgc
    44461 tgattgcgct tgtccagacg ctgcgtggca aaatcgacca gcatcgctgg gtgctgaaaa
    44521 tggcgctctg gagtttgccg ctgccgtgga ttgcgattga agccggatgg tttatgaccg
    44581 agtttggtcg tcagccgtgg gcgatacagg acatcttacc gacatactcc gcgcactccg
    44641 ccttaaccac aggacaactg gctttctcac tgatcatgat cgtagggctt tacaccctgt
    44701 tcttaatcgc cgaagtctac ctgatgcaga aatatgcccg tctggggccg agcgcgatgc
    44761 agagtgaaca accgacgcag caacaggggt aaaggagaaa atcatgtttg attatgaaac
    44821 attgcgtttc atctggtggc tgctgattgg cgtgatcctg gtggtcttta tgatctccga
    44881 cggatttgac atggggatcg gctgtctgct gccgctggtg gcgcgtaatg atgatgaacg
    44941 tcggatagtg ataaacagcg ttggcgcgca ctgggaaggc aatcaggtct ggttgatcct
    45001 cgcaggtggg gcattatttg ccgcctggcc cagagtgtat gcagcggcgt tttccggctt
    45061 ttatgtggcg atgattctgg tgctgtgctc gctgttcttc cgcccgctgg cctttgatta
    45121 tcgcggaaaa atcgccgatg cacgctggcg taaaatgtgg gatgccggac tggtcatcgg
    45181 cagtctggtg ccgccggtag tcttcggtat tgcattcggc aacttgctgc tcggcgtgcc
    45241 gtttgctttc acaccgcaat tacgcgtgga atatctcggc agcttctggc aactgctgac
    45301 gccattccct ttattgtgtg gattgctcag tcttgggatg gtgattttgc aaggtggcgt
    45361 ctggttacaa ctgaaaactg ttggtgtgat tcatctgcgt tcacagctgg cgaccaaacg
    45421 cgccgcacta ctggtgatgc tgtgcttttt gctggcgggt tactggctgt gggttggtat
    45481 tgatggcttt gtgctgctcg cccaggatgc taacggtcct tccaatccat taatgaaact
    45541 ggtggcagtg ctacctggtg cctggatgaa taatttcgtc gaatcgcccg ttttgtggat
    45601 cttcccgctg ctggggttct tctgcccatt gctgacggtg atggcgattt atcgtggtcg
    45661 cccgggttgg ggatttttga tggcgtcatt gatgcaattt ggcgtgattt tcacggcagg
    45721 catcacgctg ttcccctttg tcatgccgtc aagcgtgagt ccgatctcca gcctgacgtt
    45781 gtgggacagc acttccagtc agctgacgct gagcattatg ttggtaatcg tgctgatatt
    45841 tttgcccatt gtgttgctct acactctctg gagctactac aaaatgtggg ggcgcatgac
    45901 gacagaaact ctccgccgta acgaaaacga gctgtactaa ggagcaggaa caatgtggta
    45961 tttactttgg ttcgtcggca ttttgttgat gtgttcgctc tccacccttg tgttggtatg
    46021 gctggacccg cgtctgaaaa gttaacgaag gtaagcctga tgaggcgcat tagcgtcgca
    46081 tcaggcaatc aataatgtcg gatatgaaaa gcggaaacat atcgatgaaa gcgatcttga
    46141 tcccattctt atctcttctg attccgttaa caccgaaatc tgcattcgct cagagtgagc
    46201 cggagctgaa gctggaaagt gtggtgattg tcagtcgtca cggtgtgcgt gcaccaacca
    46261 aggccacgca actgatgcag gatgtcaccc ctgacgcatg gccaacctgg ccggtaaaac
    46321 tgggttggct gacaccgcgc ggtggtgagc taatcgctta tctcggacat taccaacgcc
    46381 agcgtctggt ggccgacgga ttgctggcaa aagagggctg cccgcagcca ggtcaggtcg
    46441 cgattattgc tgatgtcgac gaacgtaccc gtaaaacagg cgaagccttc gccgccgggc
    46501 tggcacctga ctgtgcaata accgtacata cccaggcaga tacgtccagt cccgatccgt
    46561 tatttaatcc tctaaaaact ggcgtttgcc aactggataa cgcgaacgtg actgacgcga
    46621 tcctcagtag ggcaggaggg tcaattgctg actttaccgg gcatcggcaa acggcgtttc
    46681 gcgaactgga acgggtgctt aatttcccgc aatcaaactt gtgccttaac cgtgagaaac
    46741 aggacgaaag ctgttcatta acgcaggcat taccatcgga actcaaggtg agcgccgaca
    46801 atgtctcatt aaccggtgcg gtaagcctcg catcaatgct gacggagata tttctcctgc
    46861 aacaagcaca gggaatgccg gagccggggt ggggaaggat caccgattca caccagtgga
    46921 acaccttgct aagtctacat aacgcgcagt tttatttgct gcaacgcaca ccagaggttg
    46981 cccgcagtcg cgccaccccg ttattggatt tgatcatgac agcgttggcg ccccatccac
    47041 cgcaaaaaca ggtgtatggt gtgacattac ccacttcagt gctgtttatc gccggacacg
    47101 atactaatct ggcaaatctc ggcggcgcac tggagctcaa ctggacgctt ccaggtcagc
    47161 cggataacac gccgccaggg ggtgaactgg tgtttgaacg ctggcgtcgg ctcagcgata
    47221 acagccagtg gattcaggtt tcgctggtct tccagacttt acagcagatg cgtgataaaa
    47281 cgccgctgtc attaaatacg ccgcccggag aggtgaaact gaccctggca ggatgtgaag
    47341 agcgaaatgc gcagggcatg tgttcgttgg ccggttttac gcaaatcgtg aatgaagtac
    47401 gcataccagc gtgcgctctc catcaagaca aataaacatt tgccgctgtt ggtccacgca
    47461 ggccatttac gcggcaaaat tccacgcgta atcctggtat aagcacttct gcgtcgcggg
    47521 gagtgaatgc ggaaatatgg acctggactt ctttacgacc gtcggagggg ataatgaatc
    47581 ctttgccgct tttgcgatca aaggttttga caattcctgt cattttacgg gacaaacaaa
    47641 ttccttactg aaaatactgc gctgcactat acggggttaa taaaataaag ccagcgatat
    47701 ttaagaccgc cggacggcta aaataaaatt tgcttaatct caattatcat gcgttaatag
    47761 ctgcgtcggt ttgaaagaca gacagcatac aaagtagttt actaaagcag ttctcattat
    47821 caggcattat ccccttcttt tgagtctctc tcctgaacac taagtagttt ctgtattaaa
    47881 gccctgtttg ccgaaaggcc caaaatgaag gaagtaaaat atgtctaata aaatgactgg
    47941 tttagtaaaa tggtttaacg cagataaagg ttttggcttt atcactcctg atgatggcag
    48001 caaagacgtt ttcgtccatt tcactgccat ccagagcaat gaattccgca cgctgaacga
    48061 aaatcagaaa gttgaatttt ctattgagca ggggcaacgt ggtcccgcgg cagcgaacgt
    48121 tgttacgctc taaggttgcc gttattactc aacatctcca tttccgctgt ccatgttgcc
    48181 atggttcaca gtaccgcaca tcggcattcg atgtgacgga gcgaaaccct ttgggtgcaa
    48241 agtgcatttt ttgtaaatcg acgatgatca cctttgataa cgttgcgctg caaatacgca
    48301 ctgaccatgc gccgctggat ttcacaaaat aatatcaggc tccctcgtgg agcctttttt
    48361 atatctgcct tatttttctt caacgctgta tgtatagtaa gcgataacct gttgattatt
    48421 gaatctttcg gggagatggc ttataacatt tcttacctga ccagggtacc gggaaccaac
    48481 accttactgg cgtgttgctg tcttttaaga ccagaagagg ttaacagtga atattgaaga
    48541 gttaaaaaaa caagccgaaa cggaaatcgc cgactttatc gcgcaaaaaa tcgccgagct
    48601 gaacaagaat acagggaaag aagtctctga aattcgcttc accgcacgag aaaaaatgac
    48661 cgggcttgaa agttatgatg tcaaaatcaa aataatgtga ttttgtgaac atcaccccgt
    48721 gcgaggtgat gttccgcttg ttgctaattt agtgaccaat cattggcgat tgcggaatta
    48781 agcgttggta caattcctcc ggcaccgggc tttgccatac tcccgcatac attgcgtaac
    48841 caatcgccgc aaacataatc cccataacca gtagcgtcat taaccagcca gacaacgcaa
    48901 aggctttttt atttgccgca ggtttttgca gtgaaaaggc caatgttgag gctaccggac
    48961 atgactctac gcaagtcata cagccggtac attccactgt tcgtacctga attaatttat
    49021 cgaccgggat ccgtgatggg caactttttg cgcatttgcc acaatcgata caactttcgg
    49081 cattgcgacg aatcttaaac ggcgataata gcgaaaccac gcccatcagc gcgccatatg
    49141 ggcaaagata acgacaccag gcatggcgaa taaacaggct ggcaatcagc aaaacgatca
    49201 tgctgattaa tgtcgcggtc cccatatgac gaaagaaatc gagcatttta acgtccatca
    49261 ccacgctgta gggcgacaac ataaaatagt gaatcgcctg agcgggcatc aataacgcga
    49321 tatagagaaa aaaactcaac agcaaatact tcacgccgcg cagaggaata tccagccagc
    49381 ggggaaggac aaattgccga ccaaacagtt tgttaccgag atcgccgatt aattccgaaa
    49441 gcgtaccaac cgggcataac catgaacaaa aggccttttt gagtaataga ctgatgacga
    49501 taaaagcgac caataacagc atcgcggcgg cgtggacgga cggtaactga cctgttgcaa
    49561 ggctatattt cagattcatc agaccggcaa tcggtagcca gccttcgata ccacccggtc
    49621 tggtgacaaa tgtcgtacta cctgccgttt cgtaatagcg cacccaatac cagaacgtga
    49681 tggcaatata aatattaatt gccaacagta ataattgcgt cgctttacgc caggtcgtgg
    49741 cattgcgcca gtcattccac ggtaatttgc cgcccgtcgt gcctggccgc cgttgccagc
    49801 gggttctttt tttctctgcc atgattttgc cagtccgtta agttgcatac caaatgccac
    49861 tattctagtt gttcttaact ggctgatatt gattcaaatc gcgttcaggt ctttcttatt
    49921 aaccatgctt ccagagcggc aacactgcgt gtaatttctt cgtgtggaag gggggcagat
    49981 aatggctgct gctccagttg tgcgcattgc tggctggcgc tacgcattcc cagactcgag
    50041 caactgcttt ttagctgatg tgcggcacgc tttattttct cgttatcctg actggcgcgg
    50101 gcaatgtcga tttcatcgag aagcggcagg gcatgttgtt taaataatat cagccattcg
    50161 tggatcttct ccgcccccat taaatgagca tcttcattga gttgcgatac atccagtggt
    50221 tgatcgttat tgacttgcag ttggagatag tgcgccagta attgaccgag cacttcacgc
    50281 ggcaccggtt tagggataat cccgcgaaat agcgaactgg tacgctgtcg cagtgtttcg
    50341 tcaatgacat gggcgctaaa gccaatcaaa accagcgacg gatattgctg tgccagttgt
    50401 cgggcaagcg taatgccgtc gatatccggt agatcaaaat ccaccagtgc ggcagcaaac
    50461 ggttcactat tttgcagtgt ctctaaagcc tgcgcggcat ttcctacggc aacgacctgc
    50521 gccccactgc tgttcaacat ctcaacggta atccgctggg ttagcgggtt atcttcaatt
    50581 aacagcaaac gtaaaccgtc cagacgcacc gcctgattga ctgtttttgg cacgggtgca
    50641 gtggcaacac gtaacggcac gcgtaaacaa aaacagcttc caacctccgg cgtgctggtg
    50701 gcgctcaatt cgccgcccat cgcctgggcc agacggctac tgatagtcag ccccagcccg
    50761 gtgccgccgc gtttgccgct aacctgaaca aatggctgga agatttcagc cagtttcgcg
    50821 ggatcaatac cgcagccgct gtcttccact tcgaccagcc attgttcgcc atcaatgcga
    50881 ctacgcagaa taatgtgccc ttcgtcggtg aaacgcaggg cgttgctcaa caggttggta
    50941 atgacctgac gaatacgccg cggatcgccc attaacgcag tcggtacatc gtcggcaatt
    51001 tctgttgcca ggcgaatcgg gcgacctttc acccttccgc tcattaattg cagggtactt
    51061 tccagcagcg ggcgcggttc aaagggttca tcgctgaccg aaacattctt gccgcctgct
    51121 tcgatagccg aataatcgag aatatcgttg aggatggtca gcaacgattc accagagtcg
    51181 gtaatcgccc gcaaatcatc gcgctgggcg ttaagtgcgg ggttatctgc cagcagctgt
    51241 gcggtgccga gaataccgta cagcggtgtg cggatctcat ggctcatcgc cgccagaaac
    51301 gccgattttg cctggctggc tttttctgct tccgcccgtg cctgtcggtg ttctatcacc
    51361 agttcctgca attcagctgt acgcgctttg acctgcgccg ccagctgttc gcggtggcga
    51421 ttcagtgcat gaacactgct gcgaaacgca tccatcagcc gcccgatggt atccagttcc
    51481 cgtacgccag cggtttccgg gaaaggggag tcgatatcac catccagcaa gcgttgcagc
    51541 gcctgcgttt gttctgcaag agggcgcgtg actgagcgat aaaccacgcg ccagaggatc
    51601 agaatcagtg cgcaaagaga aactaatccc agcaataaca ggctgtattg cccgcgtgca
    51661 ctggcttttt ccagatgagc cagcccgtgc tgattacgca gctcaatggt gtcgaccagc
    51721 tgactgactt cgctactaaa ctgcgcgaat tgggcgatgt tattttgggc gagagtttgc
    51781 aggtgattgc tgatttcact gtcctgctga tacagcgcca gcaaatcgct atattggcta
    51841 acggtagtta acgttgttgc tacctgagta cgaacacccg gatcttcaat gcgtatttgc
    51901 cgacgttgca gaattttcac cgcattattg agctgctttt ccagcgttgg cgcatttttc
    51961 tggatctgtt ccagccccag attcatcacc atttgctgca cccgcagggc gctaaggcgc
    52021 agttcattca tctggttaac atactcaaga tcgatatcaa tcagccgatc gagtgcactt
    52081 tctgcggctt gacgctgatg ttgttcgatc aaatcgtaaa tcccggcctg ggtcgctccg
    52141 gcggaggttg ccgcattatt cgcctgacct tgcgccaggc gtgcgatttc atcggcggcg
    52201 gcgactatct gctgactgag ttgctgttgt tgctggcgaa gttgcaaacg ctgccccacc
    52261 agttcccctt gctgacgtaa cgaacgggag atctcctgct cctgttgttc aatagcggtg
    52321 gtgtcaaaac cttgttcccg taacgcttgc agcaacgcat taatcttcag actttgtgcg
    52381 gtgagcattc gcccctgcgc ctgccacatc ttttcgttat cggcactggt caggttctgc
    52441 gcggcgaaaa gttcccaggc gctggcttcg ctcaactggc gcgccatatt catggtagga
    52501 atcaatgcct gagtgttgtc tttttccacc tggctgataa agcgcaggtt gtaccatccc
    52561 accagggtac tggtcagggt taacagcgcc atcagggcaa agcccatcca gagtcttcgg
    52621 gtcagggtta aattcacggt cggtgcactt aaggtgaaaa aggttgagtc gcaaagcgga
    52681 atgcatctag cataaagcct tattattgat gaggctatca tgcgcgtact gctattttta
    52741 cttctttccc ttttcatgtt atcggcattt tcggctgata acctgttgcg ctggcatgat
    52801 gcgcagcatt tcacggtgca agcctctacg ccgcttaaag ccaaacgcgc atggaaactg
    52861 tgcgcgcttt atcccagcct gaaagattca tactggttat cgttgaacta tggtatgcag
    52921 gaggctgctc gccgctacgg tgtggattta aaagtgctgg aggcaggcgg ctacagccag
    52981 ttggctaccc agcaagcaca aatcgaccag tgtaaacagt ggggcgcaga ggccattttg
    53041 ctcggtagta gcacgacgtc atttcccgat ctgcaaaagc aggtagcaaa tctgccggtg
    53101 atcgaactgg taaatgctat tgatgctccc cacgtgaaaa gccgcgttgg tgtgccctgg
    53161 tttcagatgg gctatcaacc agggcgatat ctggtgcaat gggcgcacgg taaaccactg
    53221 aacgtgctgt tgatgcccgg ccccgataac gccgggggca gtaaggagat ggtagagggt
    53281 tttcgcgcag ccattgccgg aagcccggtg cgtattgttg atattgcgct cggtgataac
    53341 gatattgaaa tccagcgtaa cctgttgcag gagatgctgg aacgccatcc agaaatcgac
    53401 gtcgttgccg gaacggccat tgcggcagag gcggcaatgg gggaagggcg taacctgaaa
    53461 acgccgctta ccgtggtgtc gttttatctt tcacatcagg tgtatcgcgg gttgaagcgg
    53521 ggaagagtga ttatggctgc cagcgatcaa atggtctggc aaggggaact ggcggttgag
    53581 caggccatca ggcaattaca ggggcaatcg gtgtctgata atgtcagccc accgatttta
    53641 gtcatgacgc cgaaaaatgc cgaccgcgaa catatccgcc gctcgctgtc accaggggga
    53701 tttcgtccgg tttattttta tcagcacaca tcagcggcta agaaataacc ttcgccatgt
    53761 tgtgtcacca gtaaatccgc actgagttta tggcgtaaac gacgaattaa cacatcgacg
    53821 gtgcgcaggt cagggttttc cacccgacgc gcagagagca tacgcagcag acgttcacgg
    53881 ctgagaattt cgcccggatt agtcacaaat gccaccagca tttcatactc tgcgcgggtc
    53941 agtttaatcg gctcgccatc ccgctccagc gtatggcgcg acacattcag gcaataaccg
    54001 gcaaagcgat agcagttgtc ctgagtgtgc ggttgcgcct gtcgcgcgag gtcgattcgc
    54061 cagagcaaat ttttcactcg taccaccagt tcgcgcagct ccagcggttt ggtgacgtaa
    54121 tcgtctgcgc ccatttccag cccaacaata cggtcaatcc gatcgctgcg tccggtaacc
    54181 agaataatcc ctaccgttga gcgttctcgc agggcgcggg ttaacatcag gccattttca
    54241 tcgggcaaat tgatatccag cagaatcaaa tccaccggct gattctgcat aatttcccgc
    54301 agcccggcac cgctcgccgt aacggaaacg gtatacccct cctgagtgaa gtaagattgt
    54361 aatcgcgcct gggtaaccgg ctcatcttca acaataacaa tgtgatgtgg catcagaggg
    54421 ttttactcat tctgttcata tctgttcata ttctgccgta agccgttcat cctgaccagt
    54481 gccgctgttc atatttgctc attaagatcg cttcactaaa ccataatttt acaggggcta
    54541 ttatgcggaa actctggaac gcgctacgcc gacccagtgc tcgttggtcg gtactggcgc
    54601 tggtcgctac tgggattgtg attggcattg cgctgattgt attgccacac gttgggatca
    54661 aagtcaccag cacaaccgaa ttttgtgtca gttgccacag tatgcaaccg gtgtatgaag
    54721 aatataaaca gtcggtgcat ttccagaacg cctccggcgt gcgagctgaa tgccatgact
    54781 gtcatatccc gccggatatt ccaggcatgg tgaagcgcaa actggaagcg agcaacgaca
    54841 tttaccagac ctttattgcc cactccattg atacacctga gaaatttgaa gccaaacgcg
    54901 cggaacttgc cgagcgtgaa tgggcgcgaa tgaaagaaaa caactcggca acctgccgct
    54961 cctgccataa ctacgatgcg atggatcatg cgaagcagca tcctgaagcg gcgcgtcaga
    55021 tgaaggtggc agcgaaagat aatcaatcct gcatcgactg tcataaaggt attgcccacc
    55081 agttaccgga tatgagtagt ggcttccgta agcagttcga tgagctgcgc gccagtgcta
    55141 atgatagtgg tgacacgctg tactccattg atattaagcc gatttatgcg gcgaaaggcg
    55201 ataaagaagc gtctggttct ctgctgcctg cttcggaagt gaaagtcctt aaacgtgacg
    55261 gcgactggct gcaaattgaa atcactggct ggacggaaag tgcaggacgt cagcgtgtac
    55321 tcacccaatt cccaggtaaa cgcatctttg ttgcctcgat tcgtggtgat gtgcagcagc
    55381 aggtgaaaac actggagaaa accaccgttg ccgacaccaa taccgagtgg agcaagttgc
    55441 aggccactgc gtggatgaag aaaggcgaca tggtgaacga tatcaaaccg atctgggctt
    55501 atgcggattc gctgtacaac ggcacctgta accagtgcca cggcgcaccg gaaatatccc
    55561 actttgacgc taacggttgg atcggcacgc tcaacggcat gattggcttt accagcctcg
    55621 ataaacgtga agaacgcact ttgttgaaat atctgcaaat gaatgcgtct gacaccgcag
    55681 gtaaagctca cggcgataag aaggaagaaa aataatgaac aataacgatc tctttcaggc
    55741 atcacgtcgg cgttttctgg cacaactcgg cggcttaacc gtcgccggga tgctagggcc
    55801 gtcattgtta acgccgcgcc gtgcgactgc ggcgcaagcg gcgactgagg ctgtcatctc
    55861 gaaagagggc attcttaccg ggtcgcactg gggggctatc cgcgcgacgg tgaaggatgg
    55921 tcgctttgtg gcagcaaaac cgttcgaact ggataaatat ccgtcgaaaa tgatcgccgg
    55981 attgccggat catgtacaca acgcggcgcg tattcgttac ccgatggtac gcgtggactg
    56041 gctgcgtaag cgccatctga gcgacacctc ccagcgcggt gataaccgtt ttgtgcgcgt
    56101 gagctgggat gaagccctcg acatgttcta tgaagaactg gaacgcgtac agaaaactca
    56161 cgggccgagt gccttgctga ccgccagtgg ttggcaatcg acggggatgt tccataacgc
    56221 ttcggggatg ctggcgaaag ctattgcctt gcatggtaat agcgttagta cgggcggaga
    56281 ttactctacc ggtgctgcgc aggtgatcct gccgcgcgtg gttggctcaa tggaagtgta
    56341 tgaacagcaa acctcctggc cgctggtatt gcagaacagc aaaaccattg tgctgtgggg
    56401 ctccgatttg ctgaaaaacc agcaagcgaa ctggtggtgc ccggatcacg atgtttatga
    56461 atattacgag cagctaaaag cgaaagtcgc cgccggtgaa attgaggtca tcagcatcga
    56521 tccggttgtc acatccaccc atgagtatct ggggcgcgag catgtgaagc acattgcggt
    56581 taacccgcaa actgacgtgc cgctgcaact ggcgctggcg catacgctgt acagtgaaaa
    56641 cctgtacgac aaaaacttcc tcgctaacta ctgtgtaggt tttgagcagt tcctgccgta
    56701 tctgctgggt gagaaagacg gtcagccgaa agatgccgca tgggctgaaa aactgaccgg
    56761 cattgatgcc gaaaccattc gtgggctggc acggcagatg gcggcgaaca gaacgcagat
    56821 tattgctggc tggtgcgtac agcgtatgca gcacggtgaa cagtgggcgt ggatgattgt
    56881 cgttctggcg gcgatgctgg ggcaaattgg cctgccaggt ggtggttttg gttttggctg
    56941 gcactataac ggcgcaggca cgccggggcg taaaggcgtt attttgagtg gtttctccgg
    57001 ctctacgtcg attccgcctg ttcacgacaa cagtgactac aaaggctaca gcagcaccat
    57061 tccgattgcc cgttttatcg atgcgatcct cgaaccgggg aaagtgatca actggaacgg
    57121 taaatcggta aaactgccgc cgctgaaaat gtgtattttt gccggaacta acccgttcca
    57181 tcgccatcag cagatcaacc gcattattga aggctggcgc aagctggaaa cggttatcgc
    57241 catagataac cagtggacct caacctgccg ctttgccgat atcgtgctgc ctgcgaccac
    57301 gcagtttgag cgtaacgatc tcgaccagta cggcaaccac tccaatcgtg gcatcatcgc
    57361 catgaaacag gtcgtgccgc cgcagttcga ggcgcgcaac gacttcgata ttttccgcga
    57421 gctgtgccgt cgctttaatc gcgaagaagc ctttaccgaa gggctggacg aaatgggctg
    57481 gctgaaacgc atctggcagg aaggtgtaca acagggcaaa ggacgcggcg ttcatctgcc
    57541 agcgtttgat gacttctgga ataacaaaga gtatgtcgag tttgaccatc cgcagatgtt
    57601 tgttcgccac caggcattcc gcgaagatcc ggatctcgaa ccgctgggca cgccgagtgg
    57661 cctgattgag atctactcga aaaccatcgc tgatatgaac tacgacgatt gtcaggggca
    57721 tccgatgtgg tttgagaaaa tcgaacgctc ccacggtggg cctggctcgc agaagtatcc
    57781 gttgcatctg caatctgtgc atccggattt ccgacttcac tcgcagttat gtgagtcgga
    57841 aactctgcgt cagcaatata ccgtagcggg taaagagcca gtatttatta gcccgcagga
    57901 tgccagcgcg cgcggtattc gtcacggtga tgtggtacgc gtctttaacg ttcgtggtca
    57961 ggtgttggct ggagcagtgg tttctgaccg ttatgcaccc ggcgtggcgc gaattcacga
    58021 aggggcatgg tacgatccgg acaaaggcgg cgagccaggg gcgctgtgca aatacggtaa
    58081 ccccaacgtc ttgaccatcg acatcggtac ttcgcagctg gcgcaggcga ccagtgcgca
    58141 cactacgctg gtggaaattg agaagtacaa cggaacagtg gagcaggtga cggcgtttaa
    58201 cggccccgtg gagatggtgg cgcagtgcga gtatgttccc gcgtcgcagg tgaaatcatg
    58261 accacgctga cagcacaaca gattgcctgt gtttacgcct ggctggcgca gttgttctcc
    58321 cgtgaactgg acgatgaaca actgacgcaa atcgccagtg cgcagatggc tgaatggttt
    58381 tcgttgctga aaagcgaacc gccgctcact gcggcggtga atgggctgga aaacagtatt
    58441 gccactctga cagtacgtga cgatgcccgt ctggaactgg ccgctgactt ttgcggcctg
    58501 tttctgatga ccgacaaaca agcggcgctg ccgtatgcat cggcctacaa acaggacgag
    58561 caagagatta aacgcttgtt agttgaggcg gggatggaaa ccagcggcaa tttcaacgaa
    58621 ccggcagatc atctggcgat ctatctcgat ttgttgagtc atctgcattt ttcgctggga
    58681 gaggggaccg ttcctgcgcg aagaatcgac ggtttgcggc aaaaaacact gacggctctg
    58741 cgggaatggt taccagagtt tgctgcgcgt tgtcgacagt atgacagctt tggtttttac
    58801 gcggcactaa gccagttatt gctggtgtta gtggagtgtg actaccaaaa aagataatgc
    58861 cgtttgtagg cctgataaga cgcggcaggc gtcgcatcag gcattagtgc gcagttgccg
    58921 gatgcggcga gaacgcctta tccggcctac gggaacagtg ctttttgtgg gcctgataag
    58981 atgcgttaag cgtcgcatca ggcattatgg cgcagttgcc ggatgcggca tgaacgcctt
    59041 atccggccta cgggaacagt gctctttgta ggcctgataa gacgcgttaa gcgtcgcatc
    59101 aggcaacaaa ctcacgggtg agccacaaac cgggaaagcc gctggcgcag caggcggttt
    59161 tcctgcttca ggtgcgcaat atcatccatt aacgtcagcg ccaccgcgat ccccggccag
    59221 tccagagcca gttcatgacg caggcgtacc gcgcgttgca ccacaatggc ggcatggtcg
    59281 tcaaataccc aggttgtctc ctggatctca ctcggttcaa ccacccccaa accgacaatt
    59341 tcattcaact cctcttcaga gatgccggta tgcaggcaaa attcggtaat agtaaaagtc
    59401 accgtaacat tagccattat gctttccccc aatctttacg tggatcaaaa gacgactggg
    59461 cgtctgccag ttgctgccac agcgcggcag tgttttcatc cggtttcggc ggcatcacga
    59521 ttttcagtac cgcatacaga tcgccggtct gttttttgct caccagacct ttgcctttaa
    59581 cgcgcaatcg ttgcccggcc tggctgccag gcgggatagt cagcaaaatg ctttctttca
    59641 gtgttggaac ggtgacttta gtacccagcg ccgcttccca cgggctaacc ggcaccacta
    59701 tttccagatc ctggccgaca atatcaaaca gcggatgtgg cgcaatgtga atcaccagcc
    59761 acaggtcgcc atttggaccg ccgttttcgc ccggcgtccc ctggcctttc aggcggatgc
    59821 gttgaccatt gccgacgccc gccgggatct tcacattcag cgttttcggg atttcctgtt
    59881 cgatcatgcc aaaggcgtta taaaccggca ggttatagct gatggtacgc ttatgctcag
    59941 taagcgtttc ttcgaggaaa accgccactt cgatttcaat atcgtggccg cgtgtggcgg
    60001 ggcgttgacg gctctggcgg gcatgctgac cgaaaattga cgagaagata tcgtcaaaat
    60061 cttcggcgtt aaaactctga ccgtcgccat gatggaactg acggttaaat tgcggatcgt
    60121 tgcgatgttg ccacatctga tcatactcag cgcgacgttg ttcatcactt aacacttccc
    60181 aggcttcggc gacctctttg aagcgggctt cggcatccgg ttctttgctg acatcaggat
    60241 ggtatttgcg ggccagtcga cgataggcgg tcttgattgt cttgagatcg tccgtcggtt
    60301 tcacgcccat gatggcgtaa taatccttta attccatagc gttatctcgc gtaaatcaac
    60361 acaaattgaa ggaacccctg taaggtaact cctataagtg tagggtaatc ctcaaaattt
    60421 catatgccaa cacagaatat gttattgaaa tcatcgcgga ggggaggttg cctcaaggtg
    60481 ggaggaacat attttattta cctcactcct gaacttttgg ctcatgctta caagttaaac
    60541 aataaggaaa ggaatgcaca actcgactat ttaaatcgtt atgcaattta atgataaaga
    60601 catgtgctaa aaaccattgc tattagtctc acattctttt tttattggta atggtaacgc
    60661 cgctgatttt ctttatagct actgatgtaa tcattagcgg cgtaaacgag gccggggcta
    60721 atcaggcata gtttgcgtca aaacttgcct gtttttaaag gggaatatag aaaaacaggc
    60781 gttcaacgag ccattttgcg aacctgttcc cggaaaaatg acatatttct gtcacactct
    60841 ttaattattg ataacaaaag aggtgtgagg aatgaacaaa acgctaatcg ccgcaactgt
    60901 ggcagggata gttttactcg cttcaaatgc tcaggcacaa accgtaccgg aaggctatca
    60961 gctacagcaa gtccttatga tgagccgtca taacttacgt gcgccgctgg cgaacaatgg
    61021 cagtgtgctg gagcagtcga cgccgaataa atggcctgaa tgggacgtcc ccggtgggca
    61081 gctcaccact aaagggggcg tgctcgaagt gtatatgggc cattatatgc gtgaatggct
    61141 ggcagaacag gggatggtga aatcagggga atgcccgcca ccggacaccg tttatgccta
    61201 tgccaatagt ctgcaacgca ccgttgcgac cgcacagttc ttcattaccg gcgcattccc
    61261 ggggtgtgat attcctgttc atcaccagga aaaaatgggc actatggacc ccacctttaa
    61321 cccagtgatc accgatgatt ccgccgcatt cagtgaacag gcggtggcgg caatggagaa
    61381 agagctcagc aaactccagc ttaccgacag ctacaagcta ctggaacaaa tcgttaacta
    61441 taaagattct cctgcgtgta aagagaagca acaatgttcg cttgtagatg gcaaaaatac
    61501 ctttagcgcg aagtatcaac aagaaccggg cgtttccggg ccgctgaaag tcggcaactc
    61561 gctggtagat gcgtttactt tgcaatacta cgaaggtttt ccgatggatc aggtggcctg
    61621 gggagaaatc aaatctgacc agcagtggaa ggtgttgtcg aagctgaaaa acggttacca
    61681 ggacagcctg tttacctcac cggaagtggc gcgcaatgtt gcgaaaccgc tggtcagtta
    61741 tatcgacaaa gccctggtca ctgaacgcac cagtgcaccg aaaatcacgg tattagttgg
    61801 gcacgactcc aacattgcct ctctgttaac ggcgctggat ttcaaaccgt atcagttgca
    61861 tgaccagaac gaacgcacgc cgattggcgg caaaatcgtt ttccagcgtt ggcatgacag
    61921 caaagccaat cgcgatttga tgaaaattga atatgtgtac cagagtgcgg aacagttacg
    61981 taatgccgat gcgttaaccc tgcaggcacc tgcgcagcgc gtgacgctgg aattaagcgg
    62041 ttgcccgata gatgccaacg gtttttgccc aatggataag tttgatcgcg tattgaatga
    62101 agcggtgaaa taacagaaaa ctcccccgcg tgaagcgggg gagtcgctgg ttaaacgttt
    62161 ttacgttcga tggtctgttc gccccaaaaa agcgaatctt tatcggtctt agcaaaggct
    62221 ttgactaaca cttcatcgct accttcttcc caaatctttt ccgccatttt ttcgtcgtac
    62281 ccggcgactt cgaaaatggc ctcggctatt tccggcgacg tattgcgcag agatgcccat
    62341 tcaccgacgt gatgagcttt cgcttcttga gttggcatgc gtatcctcct gttgaagatt
    62401 agccgttaag tttaactgcc agacctgcga catattcccc ttgataacga gcaatagaca
    62461 gttcttcctg gctgggctgg cgtgaaccgt caccgcctgc gatggtggtt gcgccgtacg
    62521 gcgtaccgcc gcgaacctgt gaaacgtcaa ataattcctg cgctgcgtag ccaatgggga
    62581 caatcaccat gccgtgatgc gcaagggtcg tccaggtgga tgtgatggtt tgttcctgac
    62641 cgccgccagt accggtggaa ctaaagacgc tcgccagttt tccgtatagt gcgccggaag
    62701 cccacaggcc gcccgtctgg tcgaggaagg tacgcatttg accggacatg ttaccaaagc
    62761 gggtaggtgt accaaaaata atggcgtcgt aatcggccag ttcttgcggg gttgcaaccg
    62821 gtgcagtttg cgttttaccg cctgcttttt caaataattg cggcggcatg gtttccggta
    62881 cacgcttaac gacaacttct gcgccatcca ctttgcttgc accctcagca actgcgcgag
    62941 ccatcgtttc aatatgtccg tacatggaat aataaagcac cagaacttta gccatttcta
    63001 accactcctc gtgttatctc tattccgtag cgattcgcta ccacttattt aaagataaga
    63061 cgtccttttc agagtgcaaa tttcacaacc acttatttga tttataacaa ctttcacaag
    63121 cacgtaattt tgtcgcaaaa tgacacattt ttatctcatc gcgttttttt aatcataaga
    63181 gcggcttatg gataattatt ggagatgata tctattctcg ctaagaagct gttgcaggat
    63241 attaccaaac gcggatctgc ccgcgtcagt tcactaagct tagttccacg tagcgaaaat
    63301 atggcagccg ccatacgccg cgttaattct atgcaatatg atgtctatac ccagacggag
    63361 gtcagtaatg gcaaaccatc gaggcggttc cggcaatttt gcagaagacc gcgaaagagc
    63421 atcagaagca ggtaaaaaag gtggacagca cagcggaggt aatttcaaaa atgacccgca
    63481 gcgcgcatct gaagcaggta aaaaaggtgg caagagcagt cacggtaaaa gcgacaacta
    63541 gccgggctaa tcaatgacgc atgcattttt gtctgtagct cgtcaaaacg ccatcaccgc
    63601 cggtagcccc ggcggttttc tgtttatggc ttctgatgaa caacttctgg cggtggaacg
    63661 tcaaccaacc ttctgcttaa caacgcattg agtaaaatcg cgccaaaggt ggctgtaccg
    63721 atccctccca acgtaaaacc gcccagtgtg agagcaaaat cacccgcacc cagcactaag
    63781 gttactgcga ccataatcaa attaccgttc tggcttaaat ccacactgtt ttgtacccag
    63841 atccgtgcgc ctgcgacggc aatcagcccg aacacaacaa ttgatgcacc accaatcacc
    63901 gcagccggaa tagtatggat cagcgcgcca aatttcggcg aaaagcccaa cagcatggcg
    63961 atgacggcag cggcaacaaa caccagcgtc gagtagactt ttgtcacggc catcacaccg
    64021 atattctcgg cgtaggtggt tatgccgcta ccgccgacag agccagaaag catcgtcgcc
    64081 agcccatcgc ctacgaatgc ccgccccata tacgggtcca tattgcgtcc ggtcatcccg
    64141 gcgaccgcct tgagatgacc taagttttcc gccaccagaa tcaccgccac gggcgcaatc
    64201 agcatcattg cctgaccatt aaaagcagga gtggaaaaat gtggcagacc gaaccaggca
    64261 gcatggctga cgagagtaaa atcgacggct tttcccagcc ctaaaacgtt ggtcatcacg
    64321 ccatacagca gacaggcgac aattaatcct acgagaatca ataatcgctg gatcatgcca
    64381 cgggtaaata cggccaccag cccaatacac agcaccgtca ttaccgccat ccagctatca
    64441 aaggccgaag ccgatacatt tttcactgcg ataggcgcta agttcaggcc aatcgccatc
    64501 actaccgcac ccgtcacaac cggcggcatt agtcgttcaa tccagcgcgt accgattttc
    64561 atcaccacca ggccaatgac ggtataaacc agcccacagg cgataatccc gcccagcgcg
    64621 atgctgatgt tcggattaat tccctgacca ttaaagcccg tcgcggcaat caccacgccg
    64681 acaaaagccg cgctggaacc gagataactg ggcacgcgcc cgccggtaat aaagaaaaac
    64741 agtaacgtgc cgatccccga cattaaaatg gaaagattgg gatccagccc catcagaatc
    64801 ggcattaaca ccgtcgcgcc aaacatcgcc accgcgtgtt gaacgcccat tactgccgtt
    64861 tgagcaaacg gcaatcgttc gtccggcgcg accacgccgc tctctgtaga ggtcgatttt
    64921 aactgccagt gaggaaaacc gaacattgcc atcagctgtc tccttaagga ggttaacaag
    64981 cagggcgcat cagcgcgtga taactgcgat cgaaccacac cagcccgtag ggtgtggcgt
    65041 gacgatgaat cgcttcgatg gcgcaaaaca aaatgtcgtg ggtgccgacg ctcaccacct
    65101 ggctgatacg gcagtcaaac gaaaccagtg ccttttccag ttgcgggcat ccggtcacac
    65161 cagtctgcca gcgggcggcg gcaaagcggt gttccatggg cgttttgccg ccaaaaaggt
    65221 ttgaaagcgg ctcctgcccg gcgctaagtg tatttacaca cagcgttcga ttttcattga
    65281 ataccggcca gacggacgcc ccacgattca ggcacaccag taatgtgggc ggcgtgtcgg
    65341 tcacgctgca gacggcgctg gcggtgaacc cggcgcgccc ggctggaccg tccgtagtga
    65401 tgatattgac cgccgcgccc atacaggaca tcgcatcgcg aaaggtttgt tgatcgacaa
    65461 tgttcattgt ttgctcctta caacagcccg caggcttctt caaaggacag acgtggcagg
    65521 cgcgcaaaaa gtttgctgga atcgccatag ccgatattaa tcagcagatc gctcttcagc
    65581 gtgctgcccg caaaaaaggc gtcgtcaacg tattgacggt caaagcccga catcgggccg
    65641 gtatccagcc ccagcgcacg gcaggcgacg atcagatagg ccgcctgcat ggaactgttg
    65701 cgaaacgctg tttcttcggc aagttgtgga ctggaggtaa accaactgcg ggcatcgccg
    65761 tgaggaaaca gctgtggtaa ccgttcataa aattcactgt cccaggcgac gatagcggtg
    65821 acgggcgcgg tcagggtttt ttgcagattg ccgctggaaa gcgccgggcg cagacgttct
    65881 tttccttctg cagtgcggat aaacacgatc cgggccggag aacagttagc tgatgtcggc
    65941 ccccatttca tcagggcata aatctcccgt aacgtctcat cgctgacggg gggctcccgc
    66001 cagccgttgt gagtgcgggc atcggtgaac agggtgctaa gcgcacctgg gctaacggct
    66061 tcgttcatag caattcctta cagagcggct tcacggtgat gtaacaggct ggcaagcccg
    66121 ttgagtaaca gagcattaaa cgtttcggga tcggtcacgt tgcaggcgtg tccgccatag
    66181 cgcatcacca ttttctggct atcgggcagg gcggcatgaa gttcactgga acatgctgtt
    66241 ggcaccagca gatcgtcact ggcgcagatg atttgcaccg ggcagcggat acgatccgca
    66301 tggtgactaa agtcagcgcg tttgagggcg ttaagtcgac gcagtaaatt atttttgccc
    66361 tgaaaatgcg ccagtgccag cgcatcttct gcctcaaggc gaggtgcgcg ggccgccatc
    66421 cagtcggcgg gatagaggaa caacggctgc gcttccaccc atgcctgcgc gccgccgcta
    66481 tgtagtaact gttcgcgaac ctgaaaacag cggcgcgtat gggtgtttat tcgtagccag
    66541 ccgttaacgc tgaccagcac agttaccgac gcgggataat ccagcgccag ctgcattccc
    66601 accagcgcac cgagcgcatg gccgaccacc gcgtaacgct caatccctgc ggctaccagc
    66661 gcctgatgca gttccgctgc catctgggcg atactgtaat cttctgccag cgtgtcggga
    66721 ttattgccgg tgccgcgctg gtcgtaacag actacctgat actcctgatc cagcaccgcc
    66781 agttgcggta accagtaact gccgctaccg ccaagacccg aaatcaacac cactacgggc
    66841 gcatcagcat aagggggagg tgagagtgaa agtttcatcg cggcctcact tggcgatatg
    66901 cgcaattgtg gcgatttcca ccagcgcgtc aggttttacc agtccgcact gaatgcagaa
    66961 tcgcgccggt ttgtcacccg ggaaaaactc ggcgtagatt tcgttaatcg cggcgtaatt
    67021 tttccagtcg gtaataaaga tgctgttgaa agtcacatcc gccatcgtgc cacccgccgt
    67081 ctcgatgacc ttgcggatgg tttccagaac gtggcgggtt tgcgcctttg ggtcatcggc
    67141 aaacagcacg ttgttatgtt gatcaaaagc cagcgtaccg gagacataca ccacgccatc
    67201 agccagcgtg ccgggaacga agggggccag cggtgcgctg ctgccagcag gaataattac
    67261 ggattttggc atcgttaaac tccttaagcg atacgagcaa aggacgtgga agaaagcgcg
    67321 tcgcagaacg tttcgacgtc gctgacccag ccaaaaaagg tttcgatatt gaacaacgca
    67381 gctttctgtg caaattccgg ccccgcctgg tgtgttgcgt cttccagcac cacgccgaaa
    67441 tactccagaa aaaagccgtc gcgtagcgtc gattcgacgc agacgttggt agcgataccg
    67501 gtgaaaacca gatggcgtat tccacggctg cgcaaaatgc tgtccagcgg cgtattgaag
    67561 aaaccgctgt agcgcggctt cggcagcaca atatcgccag gctgcggcac cagttcatcc
    67621 accagttgat aatcccagga gcctttcgcc agcaatttcc cctgcagctg cggctgctta
    67681 cgcatggttt tcagggcgtt cgatttatga aaattcggtg agccggggcc gccagcctcg
    67741 acatactgtt catcccagcc attttgaaac cagatgatca gcatccctgc cgctcgcgct
    67801 gcggtcacgg cggtttgaat gttggcaatg accgggcgag tggttgagac atcaaacccg
    67861 gcgagatcta agtagccgcc tggcgtggca taagcgtttt gcatatccac cacgatcagc
    67921 gcactttgct gcggatcgaa ggtaatggct tccggtcgag cggttaaggt cgtcatcatg
    67981 ccacctcctg agtcagcgca gggagatggg cgcggcactg catcagtggt tgaatgcgct
    68041 cgccgaaggt ttcgattccc gacagaaaat catcgaaggt caacagcacg ccttcggcac
    68101 caggcacgtt tgcgacttca tctaacatgc gcgcgacact ggcgtaagaa ccgactaacg
    68161 tccccatatt gatgtttacc gccgaagtgg gatcggccat ctgacggacg ttggtgtcag
    68221 tacctgagcg ggtatctttc tgactttgtt cggttagcca gcttaacgcc tcttcatccg
    68281 cgcccgcttt gtagtgttcc cattttgcac gagcggcatc gtcggtttcg tcggcaatca
    68341 ccataaacaa cacataagag ccaacgtcgc gtccggtttg ctctgcggcc tgtttcatcc
    68401 gcgcagcggt cggggcgaaa gccgtgggtg tatttacgcc tttgccgaaa cagaagttaa
    68461 aatcggcata ccgggcggag aacgccatgc cagcgtcgct ttgcccggcg cagatcactt
    68521 tcatggggac actcggttgc ggactgacgc gacaatcatc catagtgaaa aaatcgcctt
    68581 taaaatcgct tttccccgag ccccacaggt cgcgcagcac ctgaacatat tcggtgagat
    68641 agtcgtaacg acgggagaaa tagtcatcgc caggccagat ccccatctgc tcatactcgg
    68701 gcttctgcca gccagtcacg aggttgacgc caaaacgccc gccagagatg gagtcgatgg
    68761 ttgcggccat acgggcgacg attgccggag gtaacgttaa ggtggcagct gtcgcgtata
    68821 tctgaatgcg cgaggtcacg gctgccagcc ccgccatcaa ggtgaacgac tcaaggttgt
    68881 gatcccagaa ctcagttttg ccgccaaagc cacgcagttt gatcatcgac agggcgaaat
    68941 cgaaatggta gtgctccgct ttttgcacaa tggctttatt cagttcaaat gtcggcatgt
    69001 actgcggcgc gtgggtcgaa atgagccagc cgttgttgcc aataggtacg aatacgccaa
    69061 ttttcatcat caacctctct tcgtctcgta aagtgaaagt cagacggggc gctgcatcct
    69121 gcatatcctt ttcagccgcg taatggcttg tttgcaaagc ggatgccagt ttttaaaaag
    69181 tgaatgttat taatgtgtta atgttaagtt gtctaaaatg cctgaaaaaa agtggactaa
    69241 acggtcaaaa cagttgcaca taaaacatgc attcgtgcgc gatgagagtg cagaaggtcg
    69301 aggccgggcg ggggttttgc tatcctgttg ccaatctaca agaggggaga gcgcatgacg
    69361 caaggcgcag tgaaaacaac gggtaaacgt tcgcgcgcag tgagcgcgaa gaaaaaagcg
    69421 attcttagcg cagcactgga cactttttca caattcggtt ttcacggcac aaggctggag
    69481 cagatcgcgg agttggcggg tgtttcaaaa accaatctgc tgtattactt tccgtcaaaa
    69541 gaggcgctgt atatagccgt actgcggcag attctcgata tctggctggc accgttaaaa
    69601 gcgtttcgag aagatttcgc cccgctggcg gcgatcaaag agtacatccg tctgaagctg
    69661 gaagtttccc gcgattatcc gcaggcttcg cgcctgttct gtatggagat gctggcaggt
    69721 gcaccgctgt taatggatga actgacgggc gatttgaagg cattaattga tgagaaatcg
    69781 gcgctgattg ccggttgggt taaaagcggc aaactcgcgc cgattgatcc gcagcatttg
    69841 atttttatga tttgggcttc cactcaacat tacgccgatt ttgcccctca ggtggaggcg
    69901 gtgacaggcg cgacgttgcg cgatgaggta tttttcaatc aaacggttga aaacgtgcag
    69961 cggattatta ttgaggggat tcgaccacgc taatggtgcc ggaggaaggt gtaacatcct
    70021 ccggctacct gtttaaccga tcgtcattaa actggcgtta ccgccagcgg cagcggtatt
    70081 cacactcagc gaacgctcga tatacagccg ttccagaagg atattgcttt cgccacgggc
    70141 aaaaccctgc accgaaacaa ttgcaccatc ccgcgcggca acggcttcac acaatgcgcg
    70201 aagctgatcc gaatcaccgt ggaagatcac cgcatcaaat ggttgagcgg ttatattttc
    70261 cgctttcgcc agttgaatac gttcgctgac tgccgatggc aatgccttca ctaactgacg
    70321 atgcagcgca ttatccggcc acagcacctg gctacccacc gccagcacgg cggcgagctg
    70381 agtcagcgca tcctgttcat catccgcaat acacaacacg cgctcacgcg gcagcagcgt
    70441 ccaggtgttg cgttcacccg tcggccctgg caacaatcgt tgtgttcctg cctgcgccaa
    70501 ctcgccatat tgcgtacata acgcctgcaa ttctggacgg tttgccgccc attcccgcag
    70561 tgcatttagc ggctgagtca atgcggcttt caactgcgca tcgaccggat actccgcatc
    70621 ctgacgcgcg agcgtcaccg ccagcgcact ttccgggcga ttcgccagca gacggtagag
    70681 atagagcgga ccgcctgctt tcggcccggt gccggacaat ccttcgccgc cgaacggttg
    70741 caccccaacc actgcgccca ccatattacg gttaacgtac agattaccga catgcgccga
    70801 gccagtgacc tgggcgatgg tttcatcaat gcgcgtatgg acgccaagcg tcagaccata
    70861 accggaagcg ttaatctgct cgatcagctc tgggagctgg ttacggttgt aacgcaccac
    70921 atgcaacacc ggaccaaaga cctctttttg taattcggca aagtcatcca gttcgatcag
    70981 cgtcggagcg acaaaggtgc cgctttgcca ttcacgggca tcttcgctgt tttcccgcac
    71041 cgcctggaac acctgacggc ctttactacg catggtctga atatgacgct cgatattggc
    71101 tttcgcttcg ctatcaatca ccggaccgat atcggtggtc aggcgacccg gattacccat
    71161 ccggcattcg gccattgcgc cgcgcagcat tttcagcgtg tggtcggcaa tctcatcttg
    71221 caggcacagc acgcgcagtg ccgaacaacg ctgacctgca ctgtcgaacg ccgaggccag
    71281 cacatctatt acgacttgtt cggtcagtgc tgaagaatcg acaatcatcg cgttcatgcc
    71341 gccggtttca gcgatgagcg gaatagggcg accctgagcg tccaggcggc tggcgatatt
    71401 gcgctgcagt aacgtagcga cttcggttga accggtaaac atcaccccgc gcacgcgatc
    71461 atcacccgtc agttgcgcgc ccacggtttc accccgacct ggcagcaatt gcaccacgcc
    71521 tggcggtaca cccgcttcca gcaaaatggc gatcccttgc gcggcaatca gcggcgtttg
    71581 ttctgccggt tttgccagca cgctgttacc tgccgccagt gcggcagcga tctgtccggt
    71641 gaaaatagcc agcgggaagt tccacggact gatacatacc acaggcccta atggacggtg
    71701 ggtttcgtta gcgaaatcat cccgcacctg tccggcatag tagtggagaa aatcgaccgc
    71761 ttcgcgcact tcggcaatgg cgttactgaa ggtttttccg gcttcacgca ccagaatacc
    71821 aatcagttgc tgcatctggc tttccattag cacggcagcg cgatgcaaaa ttgccgcgcg
    71881 ttcagccgga ggagtggcaa accagattgg cgcgttatta accgcacttt ccagcgcctg
    71941 ttctacttca cgcggcgtgg cttcacgcac atagcccaca atatctttcg gttccgcagg
    72001 gttaataacg ggcgacatct cacctgccgc taccggttgt tccagcattg gcaaggactg
    72061 ccatttttgc agtgcactat tgagcagggc tgaagagagc gaggccagac ggtgttcgtt
    72121 agcgagatcc agccctgccg agttgtcgcg cccgtgaccg taaagatcgc gcggcagggg
    72181 aattttcgga tgcggtaatc cagtttgccc ttcctgttgc gccagttttt ctacagcagt
    72241 gactggatcg gcgaccagtt catccagtgg caaagaggtg tcggcaatac ggttaacaaa
    72301 cgaggtgtta gcaccgtttt ccagcaggcg gcgcaccaga tatgccagca gcgtttcatg
    72361 tgtaccgacc ggagcataaa tacgacacgg acggttaagt ttgccgtcgg caactttccc
    72421 ggtgacctgc tcatacagtg gctcgcccat accatgcagg cactggaact cgtactgacc
    72481 cgggtagtag ttttgacccg ccagttgata aattgccgcc agcgtatggg cgttgtgcgt
    72541 cgcgaactgc gggtagatta gatttggcac cgccagcagt tttttcgcac aggcaagata
    72601 agaaacgtcg gtatacacct tgcgggtata aaccggataa ccttcaaggc cgtccatctg
    72661 tgcacgcttg atttcactat cccagtacgc gcctttcacc aggcgaatca tcagacggcg
    72721 acggctgcgg gtggcgagat caatcaggta atcgatcacc aacgggcagc gtttttgata
    72781 agcctgaata acaaaaccga tgccgttcca gcctgccagt tcaggctcga aacagagttt
    72841 ttccagcaga tcgagggaga tctccaggcg atcggcctct tcggcatcga tgttaatacc
    72901 aatatcgtac tgacgcgcca gcagggtgag tgatttcaga cgcgggtaaa gctcttccat
    72961 tacccggtca tactgggcgc ggctataacg cggatgtagc gccgacagct tgattgaaat
    73021 gcccggacct tcatagatgc cacgaccgtt agacgcttta ccaatggcgt gaatcgcctg
    73081 ctgataggaa accatatacg cctgtgcgtc tgcggcagtc agtgcggctt cgcccagcat
    73141 atcgtaagag taacggaaac ctttctcttc cagtttgcgg gcattggcta acgcttccgc
    73201 gatggtttcg cccgtgacga actgctcgcc catcaggcgc atcgccatat ccacaccttt
    73261 gcggatcagc ggttcaccgc tcttaccgat aatgcggttc agcgagcggg agaggctggc
    73321 ttcgttatgg gtggaaacca gtttgccggt aaacagcagc ccccaggtag cggcattaac
    73381 aaacagggac gggctacgac caatgtgtga ctgccagtta ccgttactga ttttgtcgcg
    73441 aattaacgcg tcacgggtgg ctttgtcggg aatacgcaac aacgcttccg ccagacacat
    73501 cagcgccacg ccttcctgcg atgacaacga aaactcctgc aataacccct gaaccatacc
    73561 tgcgcgacca ctggcgtttt tttgattacg cagtttatcg gccagttgat acgccagttt
    73621 gtgcgcctgt tcagcaactg gctgcggcag gcgagcttgt tccagcagca tagaaaccgc
    73681 ttcggtttcc gggcggcgat aggccgcggt gatcgcggcg cgggaaaccg actggggcaa
    73741 tatttgttcg gcaaagtcga ggaaaggctg gtgtggttcc tctgccggag tcggtgcttc
    73801 atcgctctca ttggccgcgc cagaaagcag cgcaggtagc tccgggagag tatcgctgtt
    73861 ttccagttgt tcaagataag aaaaaatcgc ctgtttaatt aaccagtgtg gtgtgcgatc
    73921 gatacgtgtc gcagcagact taatacgctc acgcgtcgcg tcgtccagct taacccccat
    73981 ggtggtggtt cccatgccat tactcctgtt gttctgaaag gtgcaactta acgttatcgt
    74041 gaaatatcca tgatgttgca actttgtgca accatgttaa atgtgacctg cgtagcaagc
    74101 ttaaaaatga atgaaatgtt aataaacgaa atcgatatga cagggattaa aaaaataact
    74161 cagacttttt ctctgcggca gttaacattt ttgaaaggtg caaccgcaaa aaatgtgaga
    74221 gagtgcaacc tgatgaaaaa tagtgtcgct gagcactaaa atttaatgta aatggtgtgt
    74281 taaatcgatt gtgaataacc agcgcttccg gcaggatacg gtcgccctgg taaaacataa
    74341 actctgttac cccgttccgg tggcagatat aacggcaagt ttcgacattg ccgataataa
    74401 ttttttggag actttagatg gctattagca caccgatgtt ggtgacattt tgtgtctata
    74461 tctttggcat gatattgatt gggtttatcg cctggcgatc aacgaaaaac ttcgatgact
    74521 atattctggg cggtcgtagt cttgggccat tcgtgacggc attatcggcg ggtgcgtcgg
    74581 atatgagcgg ctggctgtta atggggttgc ctggcgctgt ttttctttcc gggatttccg
    74641 aaagctggat cgccattggc ctgacattag gcgcgtggat caactggaag ctggtggccg
    74701 ggcggttgcg tgtgcatacc gaatacaaca ataacgcctt aacattgccg gattatttca
    74761 ccgggcgctt tgaagataaa agccgcattt tgcgcattat ctccgcgctg gttattttgc
    74821 tgttcttcac catttattgc gcttcgggca ttgtggcagg cgcgcgtctg tttgaaagta
    74881 cctttggcat gagctacgaa acggctctgt gggcgggggc tgcggcgacg atcctttaca
    74941 cctttattgg cggtttcctc gcggtgagct ggactgacac tgtacaggcc agtctgatga
    75001 tttttgccct gatcctgacg ccggttatcg tgatcattag cgtcggtggc tttggcgact
    75061 cgctggaagt gattaaacaa aagagcatag aaaacgtgga tatgctcaaa gggttgaatt
    75121 ttgtcgccat tatctcgctg atgggttggg ggctgggtta cttcgggcag ccgcacatcc
    75181 tggcgcgttt tatggcggca gattctcacc acagcattgt ccatgcgcgt cgtattagta
    75241 tgacctggat gatcctctgc ctggcagggg cggtggctgt tggtttcttt ggtatcgctt
    75301 actttaacgg gcacccggcg gtagcaggtg cggtaaacca gaacgctgaa cgcgtgttta
    75361 ttgaactggc gcaaattctg tttaacccgt ggattgccgg gattttgctg tcggcgattc
    75421 tggcggcggt aatgtcaacg ttaagttgcc agctgctggt atgttccagt gcaattaccg
    75481 aagatctata caaagcattt ctgcgtaaac aggccagcca gaaagagctg gtgtgggtag
    75541 ggcgtgtgat ggtgctggtg gtggcgctgg tggcgattgc gctggcggca aacccggaaa
    75601 accgcgtgct gggcttagtg agctacgcgt gggcaggctt tggcgcggcg tttggtccgg
    75661 tggtgctgtt ctcggtgatg tggtcacgca tgacgcgcaa cggtgcgctg gcggggatga
    75721 tcatcggtgc gctgacggtt atcgtctgga aacagttcgg ctggctgggt ctgtacgaaa
    75781 ttattccggg ctttatcttc ggcagtatcg ggattgtagt gtttagtttg ctgggtaaag
    75841 cgccgtcagc ggcgatgcaa aaacgctttg ccgaggccga tgcgcactat cattcggctc
    75901 cgccgtcacg gttgcaggaa gggtaaggga aggcgtttta ccgaaaattt cacgtcataa
    75961 caggaagcag gcagagggca atcagtgatt gccctctgcg ttttttctca aaatattttt
    76021 acatcttctc atcattatca ctacatttca cttgtatttt tcttcatcgt aatgataatc
    76081 gctatcactg cgatttactt ttctttgcat agattgacta agaaaaacgt ttaagggtgg
    76141 gtggcatgtt tgttccgttt ctcattatgt tgcgcgaagg acttgaagcc gcgctgattg
    76201 tcagtttgat tgccagctat cttaagcgta cccagcgagg ccgatggatt ggtgtaatgt
    76261 ggattggcgt gttgcttgcc gctgcgttgt gcctgggctt gggtatcttc attaacgaaa
    76321 ccaccggcga atttccgcaa aaagaacagg aactgtttga aggcattgtg gcggtgatcg
    76381 ccgtggtgat ccttacctgg atggttttct ggatgcgcaa agtgtcgcgc aacgtcaaag
    76441 tacaactgga gcaggcggtc gatagcgcat tgcagcgtgg aaatcatcat ggctgggcgc
    76501 tggtgatgat ggtctttttt gccgttgcaa gggaagggct ggagtcggtc tttttcctgc
    76561 tggcggcatt tcaacaagat gtcgggatct ggccgccgct gggtgcaatg ctcggtcttg
    76621 ctacagccgt ggtgcttggc ttcctgctct actggggcgg tattcgcctc aatcttggtg
    76681 cattttttaa atggaccagt ctgtttattc tcttcgtcgc cgcagggctg gcagctggtg
    76741 ccattcgcgc atttcatgaa gccggattgt ggaaccactt tcaggaaatc gccttcgata
    76801 tgagcgcggt gctctcaact cactcgctgt ttggcacact gatggaaggg atttttggct
    76861 atcaggaagc accgagcgtc agcgaagtcg ccgtctggtt tatttatctc atcccggcgc
    76921 tggtggcatt tgttctgcca ccacgcgcag gggcgactgc gtcccgctcc gtgtagcaaa
    76981 tacgacgcaa actcttgctt agttacaaca tactttaaag ggatagtctc gtcatgacca
    77041 ttaacttccg tcgtaacgca ttgcagttga gcgtggctgc gctgttctct tctgctttta
    77101 tggctaacgc cgccgatatt ccgcaagtca aagtcactgt gacagataag cagtgcgagc
    77161 cgatgaccat tacggttaac gccgggaaaa cacagttcat tattcagaac cacagccaga
    77221 aggcgctgga gtgggagatc ctcaaaggcg tgatggtggt ggaagagcgg gaaaatatcg
    77281 cccctggttt tagccagaaa atgacggcga atttacagcc tggcgaatac gatatgacct
    77341 gcggtctgct gactaacccg aaagggaagt tgatcgtcaa aggtgaagca acggcggatg
    77401 cggcgcaaag tgatgcgctg ttaagtcttg gtggtgcaat tactgcatat aaagcgtatg
    77461 tcatggcgga aaccacgcaa ctggtgaccg acaccaaagc ctttaccgac gctattaaag
    77521 caggcgatat cgaaaaagcg aaagcactgt atgcgccgac gcggcagcac tatgagcgca
    77581 tcgaaccgat tgctgaactg ttctccgatc tggatggcag cattgacgcc cgtgaagatg
    77641 attacgagca aaaagccgcc gatccaaaat tcaccggttt ccaccgtctg gaaaaagcat
    77701 tgtttggcga taacaccacc aaagggatgg ataagtatgc tgaccagctt tataccgatg
    77761 tggtcgattt gcaaaaacgc atcagtgaac tggctttccc tccttcaaaa gtggtcggcg
    77821 gtgcagccgg actgattgag gaagtggcgg ccagcaaaat cagcggtgaa gaagatcgct
    77881 acagccacac cgatctgtgg gatttccagg ctaacgttga aggctcgcag aaaattgtcg
    77941 atctgctgcg tccacaacta caaaaagcga atccggaact gttggcaaaa gtcgatgcca
    78001 acttcaaaaa ggtcgatacc attctggcga aataccgcac taaagagggt tttgaaaatt
    78061 acgacaaact gaccgatgcc gaccggaacg cactgaaagg accgattact gcgctggcgg
    78121 aagatctggc gcaacttcgt ggtgtgctgg ggctggacta agcgttatgc agtatgaaga
    78181 tgaaaacggc gtgaatgaac cgtcacgccg acgtttactg aaagggattg gtgcgctggc
    78241 gctggcggga agttgtccgg ttgctcatgc acaaaaaacg caaagtgcgc cgggtacgct
    78301 ttcaccggat gcacgcaatg agaaacagcc gttttatggt gagcatcagg cagggatcct
    78361 gacaccacaa caggctgcaa tgatgctggt ggcgtttgat gtgcttgcca gcgataaagc
    78421 cgatcttgaa cggttgtttc gcttgttgac tcagcgtttt gcttttctga ctcagggcgg
    78481 agcggcacca gaaacgccaa atccgcgcct gccaccactc gattccggca ttcttggcgg
    78541 ctacattgcg cccgataatc tcaccatcac gttatcggtg ggtcactcat tgtttgatga
    78601 gcgctttggc cttgcgccac agatgccaaa aaagttgcag aagatgacgc gtttccccaa
    78661 cgactcgctg gatgcggcgt tatgtcatgg tgatgtgttg ctacaaattt gcgccaacac
    78721 ccaggacacg gtgatccatg cgctgcgcga tatcatcaaa cacacgccgg atttgctcag
    78781 cgtgcgctgg aagcgggaag ggtttatttc cgaccacgca gcgcgtagta aaggcaaaga
    78841 gacgccgata aatttgctgg gctttaaaga cggcaccgcc aatcccgata gccagaatgc
    78901 gaagttgatg caaaaagtgg tgtgggtgac ggcagatcag caggagcctg cgtggacaat
    78961 cggtggcagc tatcaggcag tacgcttgat tcagtttcga gtggaatttt gggacagaac
    79021 gccgctgaaa gagcagcaga cgatatttgg tcgtgataag caaaccggtg cgccgctggg
    79081 catgcagcat gagcatgatg ttcccgatta cgctagcgat ccggaaggga aggtgattgc
    79141 gctggacagc catatccggc tggcgaatcc ccgcacggcg gagagcgagt ccagcctgat
    79201 gctgcgtcgt ggctacagtt attcgttggg cgtcaccaat tccgggcaac tcgatatggg
    79261 gctactgttt gtctgctacc aacacgatct ggaaaagggc ttcctgacag tacaaaaaag
    79321 gttgaatggc gaggcgctgg aggaatatgt caaacctatc ggtggcggct atttctttgc
    79381 gctgccgggt gtgaaggacg cgaacgatta tctcggaagc gcattattgc gggtttaatg
    79441 tttttaggcg tataaggcgt ttacgccgca ccaggcgttc gtgcgctgat gcgacgcttg
    79501 cgcgtcttat catgcctaca atcggtgcgg gtcggtaggc cggataaggc gttcacgccg
    79561 catccggcaa gcttttacca gtaccgcgaa tcctgctgaa agcacacagc ttttttcatc
    79621 actgtcatca ctctgtcatc tttccagtag aaactaatgt cactgaaatg gtgttttatg
    79681 gttaaatata agtgaatata ttgttgcaat gaatgcgaaa tctgttgtac ttattaagta
    79741 gcagcggaag ttcccggcag tgatagtcag tcactatgga gatcgcggat ggtaacgtcc
    79801 tgtactggac atgttttaga gaatcagcgc gccaccactc gcggagattt ctcctccggt
    79861 agtcatctcg tcactttgta ttttcaacct catcctttct tttcatgtgt taccgacgcc
    79921 gtaaacggtg cgcgtagccg tttttcggca ttttatccaa aagcaaacta tggcttacaa
    79981 ggaagccaac cctctgatgt tcgtgcgcat aatcgcgctg ccaacggcgc gtgtgatgaa
    80041 tacaaacaac tcaaggtgct ctccatggga agacaaaaag cagtgatcaa agctcgtcgc
    80101 gaggcaaaac gtgtgctgag acgggattcg cgcagccata agcagcgtga agaagaatcg
    80161 gtcacctcgc ttgtgcaaat gagcggcgta gaagccattg gtatggcccg cgacagtcgc
    80221 gatacctcgc ccatcctcgc gcgaaatgaa gcgcaattgc actatctgaa ggctattgag
    80281 agtaagcagc tgatatttgc cacgggtgaa gccgggtgcg gaaaaacctg gatcagcgca
    80341 gcaaaagcgg cagaggccct gatacataag gatgttgaca ggattatcgt cacccgtcca
    80401 gttctgcaag ccgatgaaga tcttggtttc ttacctggtg atatcgcaga aaagtttgct
    80461 ccctattttc gcccggtcta cgacgtgctg gtccgtcgct taggggcttc ctttatgcag
    80521 tactgcctgc gaccggaaat agggaaggtg gaaattgcgc cgttcgccta tatgcgtgga
    80581 cgtacctttg aaaatgcagt cgtcattctt gacgaggcgc agaatgtgac tgccgcgcaa
    80641 atgaaaatgt ttttaacccg cctcggggag aacgtgacgg ttatcgtcaa cggtgatatc
    80701 acgcaatgcg atttgcctcg cggcgtgcgc tccggattaa gtgacgcgct ggaacgtttc
    80761 gaagaggatg aaatggtcgg gatcgtccga ttcggtaaag aggattgcgt acgttcggca
    80821 ctttgccaac gtacgctaca tgcatacagt taagtgtatt atcggtgcag agcccgggcg
    80881 aaccgggctt tgttttgggt gtttataccc ggactagcgt tttttctgaa accaccattt
    80941 ttatttgtcc ctggctggtg aaatgtacgc tcatcctgtg gcttttttgt agttgctgat
    81001 aaagctcatc aggtattgct aagctctctg catattcttg cggcgtatat tggtatgctg
    81061 catgatgctg ctgtttttga aaacgcagct tattgtacaa cgcccagacg attaacacga
    81121 cggcattcac cactgccagc aaaaaataga actgaagtcg gcttctggcc tcgctttgcc
    81181 agaaataacc cgtcagcaga tcaatggcga ataagaatat gaataaagca aataatgtcc
    81241 acaagatagt tgtggcaaca taatcaacca gtaaacgtac tggcgattgt cgggtcgtaa
    81301 taattagatt gttcatatta acctctcaga atcccacgat cgggacttac ccaacgagcg
    81361 cgttgttttt taggcatcaa catgactcgt gtaaatgata ccaacgtcgt tgccaggctt
    81421 agcatccaga aaataaccgg gaaccaaata atccagaaaa gcgatgaagc cagattgtgc
    81481 tcatagcgat tctcaatcac cagactgaca ataaattgca gtaaacataa cgtacacaat
    81541 aatattccgg cagtatgtgt cgctgcgata tgtgtcaatt caatatttaa cggtacacct
    81601 gcaagttggg ctgcgtaaat aatgaaaccg accaggcagg taaaggccca tattgtcgtc
    81661 agacagtatt caaaaaacag tggccacatt cgaaagtttt ctttgcgcca caaccttgtc
    81721 atatttttga ggaatacttc tgcaccgccc tgagcccagc gcaggcgctg attccacagc
    81781 ccttttaacg tttcaggcat taatatccag cacagcgccc gtggctcgta aaaaatcgtc
    81841 cactgattca actgcagctt ccagctaata tcaatatctt cggtgatcat atcgtcactc
    81901 cagtaaccca cttctgccag ggcgctgcga cgaaatgcgg caataacacc ggaaacggta
    81961 aatacgtttc catagatacg ctgggtccgc ttgatcaaac caataattga ggaatactcg
    82021 ccaacctgaa ttttacccac cagggtagaa cgtgtgcgaa tacgaggatt accggttacg
    82081 gcacccacac gcgggttgta caacatcggt tccacaatat atgccgctgc atcgcggtct
    82141 aataacgcgt cgccatcaat gcacaccaga tattcacttt tcgccgcggc agctccggtt
    82201 ttaagcgcaa tggctttccc ctggttttgc gccagatgaa tgacccgcag acggggaatt
    82261 tgtgcagcca tgcgatccag gatggcacgg gttttgtctg ttgaaccatc atttacggca
    82321 ataacttcaa tgttctcata acgctgtgct aaagcggcat gtatggtttc ttcaacgttt
    82381 ttctcctcat taaaacaggg aatgataatg gagatagatg gattatcttt caactggggg
    82441 gctggtgcgt tttctcccca cggccagtgg cgttcacgat agacccagaa atagacgccg
    82501 ccaataatcc acataatgga cataaaaaac ggccagaaga aaacgaacct catcatcagt
    82561 tcaccagagt gaaagtacgc tacgcatagg ggtatgcata acaccagaca taatataaaa
    82621 aacgatacga tgcgattaat catttttcgg ataccaggct gttgaaaact caggacgaat
    82681 aacgtctatt tcaggttggt tatgcagaaa attgtcggga taataaccat aatttttcac
    82741 tccattcagt tgtaataggc tcatccagtg agcgagttgt tgtgaagaaa tagcctgatg
    82801 ctgaccattt ttctgccagt tttgtgcctg taattctaaa attgatttgt ctttagcctg
    82861 cgggatgctt ttcatctgat tggtcaattg tattaaccat tgatcagccg atttttctgt
    82921 gacgccttcc atataaggca tagccataat agcggtccag tcatagcttt ttaggaaatc
    82981 agcataattc tgtgcaaacc aggcttcact ttcaggttgt attaccggaa gtgcaaaaat
    83041 atttcgtgca gttttaacat gtggaccacg aatggctttt acgcgcgcac taagttctaa
    83101 agtgaagtca gctaacgcac gacttttaaa gcgggtccac tgtttaaatt gctccgggtt
    83161 ttgtcgaatt tcgctcagac tcccgctaaa gccagcttgc tgataagccg cgatagccgc
    83221 tgcactggca tcttcataat ctgaaagcaa agcatcatcg tggaacaata tgccatcaaa
    83281 agcagcatgt ccggcaagat catcatataa cataccaact tgtgctctga ccctgtcatc
    83341 gaaaggagag agacggcggt attgttcagg atgaatttgt gcttttttct ccccagttgg
    83401 taagtatttt actcgcgtta atgtgggatc taaatcccag cttaataccg gcatccacgc
    83461 atagatgttt acacctgagc gggtacgcaa ttgccaggca acccgactaa aaatatctgc
    83521 tttcattggt agcaaacgat ttggaaacca gacctcttta accagcccat caccatcggg
    83581 atcagcaaat gcttgcaaat acacggtaga tatttgcata tcttttaccc gctgaattag
    83641 cacatcaata ttgcgatcca tttgctggcg gttttcgtca taaacgtaat caagatcgat
    83701 atgcattacc cgttgtagtg gtttttcctg tacggtaata atttgctggg caaactcttt
    83761 taatgaggga ttattggcga ttaatactcg cggaatggaa tctaattgcg acgcatttgc
    83821 caaacctgat tcaagggtga agaacatgtc ataaccgagt ttttttaatt ccgctattgc
    83881 tatgccattc gcttcgccat aaggccaaac aaaaacgtgt ggatttacct cagcctttgt
    83941 acgcaggtat tccgtcattt ttacagcatc caggcgaatt ctttcccggt attctgctgc
    84001 ggtttcatac cgtgcgtggt cagtaaaata tgcacgattt acatatgcag gcaataagct
    84061 gccggtggca ttagcctgaa taccgtagtg agaatcccat gtatgagaag cgacctcaac
    84121 gagccgggaa cgcgcaactt ctcgcacttg ttgccacgtg gcaaaatatt ctcgactgac
    84181 catctcatcg ccaaatttca cttgtttatc cgctggagta tcgacccaac tgccgacggg
    84241 agcccataca gccggccact ggaaggcctg aagaattggg aagacacggg tataaaaact
    84301 ctggtagccg tcatcaaaag tcagcactac tgctttttcc ggtagcggtt ttcctcctcg
    84361 atgtgcttca cgaatttgag caatactgac cggttgataa ccgttctcgc gcagccaggc
    84421 aaattgttca cgcagtgctg atgttcgcac tgacataaaa cgctggtcgg cagcttcgtc
    84481 ttcaacgtta tgccatgaaa tcaccacaaa accattatgt ggccacggtt gctcggcgag
    84541 taaagattcg cgatcctgtg gcggtataaa tgatgttctt gactggctaa tgcacgcggt
    84601 gagcataatt atactcacca gcatcaggag atatttattt ccattacgta acatatttat
    84661 ccttaaaatc tgaatgtcat atcgaattca acgtataagt tgtgttctct gtcaccgtca
    84721 taaggtcgtt tttcccagcg tagcgttgcg ccagcatcaa tcacgtcatt ccagctaata
    84781 cgttgcccgt agccgagttg ggtgacgaca tccgtgccat aatgtttttg ccaggaggca
    84841 ccaacacctg cgctgaatat ttgctcccag ctattttcat agcttcgcca taacaaatga
    84901 cttgcctcaa atgccggaac aatatcgaac atttttatag ggttgtagta tggggtgtcg
    84961 tgttctgtat tttgttcgta atacagattg ggtaggaaat cgacaatcaa atatggtgaa
    85021 gaccagatgc gttcttgacc ctcaattgag acttcatgac gctggttact gtcggaaaaa
    85081 tcagtgaaag cccaggagac accgtactta cgccgctcat tttgatacca gcgaacataa
    85141 gcctgtgcgc tgttgcctgt aacaccattt ttcattgccc gtaatggaac gcggtgagag
    85201 aggcgttcca gttgcgaacc aatacgccag ttatcattaa aatcatacca gccagacagg
    85261 cgcgcgccgg gtttatgctc atgattgaaa aagcgttcag cgtactccgc ctcgagccag
    85321 atattacgtg accgccactc aacacctgcc agccagtcgc gaacaatccc ttttccttcg
    85381 ctaaattgtc catcggcata accgaatcca gcaaaaccgc gccagttatc attcagcggt
    85441 ggtgaataaa cgatggtggt taagtcgaca tcatgtttgc cactatctgg accttcggca
    85501 tcaattcctg ttgagccagc gatacgaagc tctgcaagat tatgtacatc aaccgcacgt
    85561 tttaatcgta caacgccggg atcttgcggt tcacgttcga caacatcgtg ggttaagaca
    85621 gctgcctgct gccattcttg taacgttaat gctgtccagg cttgttcaac ctccagatta
    85681 atattacgtg gctcgatcac ttctgctttt tttaattcat tttctgccgc acgaggccaa
    85741 ccgcgggctt gtaacacact cgcgtaatcg atgcgcagtc cctgatttcc tggtgcgtta
    85801 taagcaagtt ctctggttgt tatttcagct tgaggaagat cattactata ttttgctacg
    85861 gttgagagaa acgaatgccc ctgtaaccag gtatcattcg ggatgctcgt aggcgtgccc
    85921 attagccgaa ggaaaggcgg cgaagtatta atggtatgtt tggtgacagt tagcgcgccg
    85981 ggataatttt cactctccag gtggctgtaa aagagatccg caagttcttc atcggataaa
    86041 tccgtggcaa tggtttcctt gttataaaag agctcggtca ttattgactg tgcttttttc
    86101 ggctgctgat ctttgagata agccgacgca acccaatata gcgcccaggg cggaataatt
    86161 tgccccgtct tttttaaacg ctgatagtga gaaataacgt ctctataacg atcgcgagtt
    86221 aataacgcgc caagatgatc aacctgaata cgctggtact gggcagtgcg gtctgggtta
    86281 tcgtgccaca gaatttctaa tgcagcgtat tgggcgaggg cgcgatcggc aatggcataa
    86341 cgttcatttt cactgcgcgt aggcataaac gacagtctga ccagttcggc atgaatatca
    86401 gcgcgaatat ctggcgttaa attggcatcg tcaatcgcgg cagctagttg attattacgt
    86461 aatgccagca cgtattctgt gggatattgt tgcttagatg cattttcagg taatgactct
    86521 gtcatcgccc gtaattcatc ctgataacgc cccgtcagtt tatagatata ggcttctgcg
    86581 agtaaattgg ctttgtccgg tgctccagat ttaagctgct taagtttaaa cagcgcagta
    86641 tcatagtgac ccgcatctgc cagggttaaa atttgtcccc gttgataatc cttattttgc
    86701 ggctccagag agagcgcctt ttgccacagt gtaagcgagt tttgccattg ttgcaggtta
    86761 cgataagcga cggcgacagc tgcataacca cgcgctggta attgctgatg acgatagcgg
    86821 ttgtaaacgg taataacctg tttatcttgc ccggcccata aggcaatctg taaccagtca
    86881 gcaatttggt tattactgag tgttgatttt tgtgcaaacc atgacaaagc tggctgagta
    86941 tttcctttgc gagcttcaat aatcaatgca tcataggcgt tattaacagc actcttcgcc
    87001 gcgggactcg ctgctaaaaa tgcagcagta agaattttca aagcccattt ggttttcggg
    87061 cacctttttc tgctacttga atacatcctg tattactcca tgtattgcca aaatctctct
    87121 ctgtatctaa ttacaggtaa ctgaaaagaa agatattttt gcatctcata atccgttatt
    87181 aaacgcggaa gagagacgtg aattgttgat gatgagaaga agaaatgatg agcagagtgt
    87241 ccatataaaa tccttttctc gcccgaaaat ccattccaat gatgaggatc ttcaggaata
    87301 cggcataaat cccaatacct ttttcaaaat aaattaggat taaaataatt aaatcagtaa
    87361 attccgatgc atgatttcgg atttttcgaa agtcctgatg aaaggcagcg ctactgcact
    87421 cacggattta attgttattc ctaatgtatc tattaattaa tgctttataa ggattttatt
    87481 ataatctttt ataagtattt gcgcctgcct tgcagcaaaa aatgtataaa gcattaaagt
    87541 gataataatt gcattctgca acta
//
LOCUS       DAPOXO010000007        84598 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPOXO010000007 DAPOXO010000000
VERSION     DAPOXO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 84598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84598
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.007"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(318..1175)
                     /gene="murI"
                     /locus_tag="ROH59_000663"
     CDS             complement(318..1175)
                     /gene="murI"
                     /locus_tag="ROH59_000663"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDX4803185.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEVFIVERVVEIVTAVQERYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFE
                     TLEKLAVLD"
     gene            complement(1120..2964)
                     /gene="btuB"
                     /locus_tag="ROH59_000664"
     CDS             complement(1120..2964)
                     /gene="btuB"
                     /locus_tag="ROH59_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HDX4803186.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDHPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQPDNDGFL
                     SKTLYGALEHNFTDVWSGFVRGYGYDNRTNYDAYYSPGSPLVDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNIIIGHGNIGAG
                     VDWQKQSTAPGTAYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGSRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     regulatory      complement(3029..3219)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            3333..4433
                     /gene="trmA"
                     /locus_tag="ROH59_000665"
     CDS             3333..4433
                     /gene="trmA"
                     /locus_tag="ROH59_000665"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HDX4803187.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPILR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWCQQAEALRDALRAQNLNVHLIGRATKTK
                     IALDQDYIDERLPIAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     gene            complement(4473..4832)
                     /locus_tag="ROH59_000666"
     CDS             complement(4473..4832)
                     /locus_tag="ROH59_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HDX4803188.1"
                     /translation="MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLV
                     LTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIM
                     VFWIGAKMRNRKQDVAE"
     gene            complement(4832..5482)
                     /gene="fabR"
                     /locus_tag="ROH59_000667"
     CDS             complement(4832..5482)
                     /gene="fabR"
                     /locus_tag="ROH59_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HDX4803189.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
     gene            complement(5586..6902)
                     /locus_tag="ROH59_000668"
     CDS             complement(5586..6902)
                     /locus_tag="ROH59_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803190.1"
                     /translation="MTAIVNETVSVKKKPSGRRVIFASAFGNALEFFDFGVYNFFVVY
                     ISTLFFPPSADHNVALLLAFATFGVSFFMRPLGGIIVGAWADRFGRKPAMVFTIALMS
                     LGTLMIGIAPTYETAGYWGTATLVLARLIQGVAAGGEVGASMSLLVESAPANRRGFYS
                     SWSLATQGLATTFGGVVALGLSAWLPFATGSETVMAEWGWRVPFFIGVLLAPIGCWLR
                     LSLENDVPEPVRNKKAATSESAFSLLLQHKATIVNGVLLAIGSTVATYISLFYYGTWA
                     AKYLAMPQHYSHAAMLLAGVVTFVGALLVGMLCDSVGRKKLILISRVMVLLCSWPSFW
                     LLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLLISELLPKRIRALGFALVYSIGVAIFG
                     GFAQYFATQSIVLLDSLTAPAWYLGGGTLLSMLALLYVKEPAKELQ"
     gene            complement(6945..8111)
                     /locus_tag="ROH59_000669"
     CDS             complement(6945..8111)
                     /locus_tag="ROH59_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDX4803191.1"
                     /translation="MIEHYIRGFEEELREIRHQIHENPELGLQEFKTSALVAEKLRQW
                     GYEVEQGLATTGVVATLKVGDGEKSIGLRADMDALPIYENSGKPWASKHPGLMHACGH
                     DGHTTILLGAARYFAETRRFNGTLRLIFQPAEEMINGGEIMVKEGLFDRFPCDVIFGM
                     HNMPGLPVGKFFFQPGALMASMDQFHITVRGCGGHGAIPHKAIDPVLVAAHITTALQS
                     IVSRNVDPLEAAVITVGSIVAGEAANVIPDSAEMKISVRSLSRDTRQLLLTRIPALAQ
                     TQAASFGATAEVTHVNGTPVLVNDEEMARFAWQVACKTFGEDRAEFGIKPLMGSEDFS
                     FMLEAQPKGGFLLFGNGDVGEGSCMVHNPGYDFNDASLVPASSYWGALVEAWLQ"
     gene            8441..9841
                     /gene="sthA"
                     /locus_tag="ROH59_000670"
     CDS             8441..9841
                     /gene="sthA"
                     /locus_tag="ROH59_000670"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HDX4803192.1"
                     /translation="MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTH
                     PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            complement(9824..10741)
                     /gene="oxyR"
                     /locus_tag="ROH59_000671"
     CDS             complement(9824..10741)
                     /gene="oxyR"
                     /locus_tag="ROH59_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HDX4803193.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(11008..12381)
                     /gene="argH"
                     /locus_tag="ROH59_000672"
     CDS             complement(11008..12381)
                     /gene="argH"
                     /locus_tag="ROH59_000672"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDX4803194.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYSNATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEDLPLSELQKFSLVIGEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLG"
     gene            complement(12442..13218)
                     /gene="argB"
                     /locus_tag="ROH59_000673"
     CDS             complement(12442..13218)
                     /gene="argB"
                     /locus_tag="ROH59_000673"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDX4803195.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGL
                     FLGDGDSIKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            complement(13226..14230)
                     /gene="argC"
                     /locus_tag="ROH59_000674"
     CDS             complement(13226..14230)
                     /gene="argC"
                     /locus_tag="ROH59_000674"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDX4803196.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDIGEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDVAFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     TTHLGADVIFTPHLGNFPRGILETITCRLKPGVSQVQVAQALQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            14384..15535
                     /gene="argE"
                     /locus_tag="ROH59_000675"
     CDS             14384..15535
                     /gene="argE"
                     /locus_tag="ROH59_000675"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HDX4803197.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQSVPGTRNKFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIMGQSGHSSDPSRGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHKLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            15837..18488
                     /gene="ppc"
                     /locus_tag="ROH59_000676"
     CDS             15837..18488
                     /gene="ppc"
                     /locus_tag="ROH59_000676"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HDX4803198.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GHEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            18671..20404
                     /locus_tag="ROH59_000677"
     CDS             18671..20404
                     /locus_tag="ROH59_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HDX4803199.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGT
                     HIKYKYRYPEDQGKFDGNTEHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAT
                     DPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            20630..21481
                     /locus_tag="ROH59_000678"
     CDS             20630..21481
                     /locus_tag="ROH59_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4803200.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGPVPDLAYQVDFPRLE
                     IVLEGEFIDTGAGAALVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQSQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(21468..21809)
                     /locus_tag="ROH59_000679"
     CDS             complement(21468..21809)
                     /locus_tag="ROH59_000679"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDX4803201.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCQLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQTHLILE"
     gene            complement(21811..22689)
                     /locus_tag="ROH59_000680"
     CDS             complement(21811..22689)
                     /locus_tag="ROH59_000680"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418387.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HDX4803202.1"
                     /translation="MTSSAGQRISCNVVETRRDDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDAAQARDVVKMNLQRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIKQIHLLPFHQYGEPKYRLLGKTWSMKEVAAPSSADVAT
                     MREMAERAGFQVTVGG"
     gene            complement(22655..24952)
                     /locus_tag="ROH59_000681"
     CDS             complement(22655..24952)
                     /locus_tag="ROH59_000681"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDX4803203.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVIMRRA
                     KATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAASCT
                     DGPRREELLTIAEISRHNAEHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQTSLTQGEDPAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRLGTGIPQIF
                     NDEVVVPAFLNRGVLLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMIFDQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGAVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            complement(25003..25323)
                     /locus_tag="ROH59_000682"
     CDS             complement(25003..25323)
                     /locus_tag="ROH59_000682"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDX4803204.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            complement(25338..26417)
                     /locus_tag="ROH59_000683"
     CDS             complement(25338..26417)
                     /locus_tag="ROH59_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDX4803205.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGVMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICVPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAVTAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTEEKEDDLDLDFEIN"
     gene            26726..29227
                     /gene="ptsP"
                     /locus_tag="ROH59_000684"
     CDS             26726..29227
                     /gene="ptsP"
                     /locus_tag="ROH59_000684"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDX4803206.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLVGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVAS
                     ANHFCEEFARSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQHQTIYIDG
                     NAGAIVVEPGESVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRQLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            29239..29901
                     /gene="fsa"
                     /locus_tag="ROH59_000685"
     CDS             29239..29901
                     /gene="fsa"
                     /locus_tag="ROH59_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDX4803207.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGMVKEAKRLRDAIPGIVVKIPVTSEGLAAIKMLKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTT
                     HL"
     gene            29912..31015
                     /gene="gldA"
                     /locus_tag="ROH59_000686"
     CDS             29912..31015
                     /gene="gldA"
                     /locus_tag="ROH59_000686"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HDX4803208.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            31291..31908
                     /locus_tag="ROH59_000687"
     CDS             31291..31908
                     /locus_tag="ROH59_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
                     /protein_id="HDX4803209.1"
                     /translation="MKASLALFSLLTVFTSYSLKSPAVPPTVVQIQANTNLAIADGAR
                     QQIGSTLFYDPAYVQLTYPGGDVPQERGVCSDVVIRALRSQKVDLQKLVHEDMAKNFA
                     AYPQKWQLKRPDSNIDHRRVPNLETWFTRHDKTRPTSKNPSDYQAGDIVSWRLDNGLA
                     HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFSWRMVGHYRYFAK"
     gene            complement(31935..32840)
                     /gene="yijE"
                     /locus_tag="ROH59_000688"
     CDS             complement(31935..32840)
                     /gene="yijE"
                     /locus_tag="ROH59_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HDX4803210.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKRI"
     gene            complement(32934..35114)
                     /gene="katG"
                     /locus_tag="ROH59_000689"
     CDS             complement(32934..35114)
                     /gene="katG"
                     /locus_tag="ROH59_000689"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HDX4803211.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGGGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(35443..36333)
                     /gene="metF"
                     /locus_tag="ROH59_000690"
     CDS             complement(35443..36333)
                     /gene="metF"
                     /locus_tag="ROH59_000690"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDX4803212.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPAELRII
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLRRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            complement(36715..38268)
                     /locus_tag="ROH59_000691"
     CDS             complement(36715..38268)
                     /locus_tag="ROH59_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDX4803213.1"
                     /translation="MKIKILAAGIALTLPFWACAKDVTIIYTNDLHAHVEPYKVPWIA
                     DGKRDIGGWANITTLVKQEKAKNKATWFFDAGDYFTGPYISSLTKGKAIIDIMNTMPF
                     DAVTIGNHEFDHGWDNTLLQLSQAKFPIVQGNIFYQNSSKSFWDKPYTIIEKDGVKIG
                     VIGLHGVFAFNDTVSAATRVGIEARDEIKWLQRYIDELKGKVDLTVALIHEGVPARQS
                     SMGGTDVRRALDKDIQTASQVKGLDILITGHAHVGTPEPIKVGNTLILSTDSGGIDVG
                     KLVLDYKEKPHNFTVKNFELKTIYADEWKPDPQTKQVIDGWNKKLDEVVQQTVAQSPV
                     ELKRAYGESASLGNLAADALLVAAGKNTQLALTNSGGIRNEIPAGAITMGGVISTFPF
                     PNELVTMELMGKQLRSLMEHGASLSNGVLQVSKGLEMKYDSNRPVGQRVITLTLNGKP
                     IEDATVYHIATQSFLADGGDGFTAFTEGKARNTTGGYYVYHAVVDYFKAGNTITDEQL
                     NGMRVKDIK"
     gene            38401..39531
                     /locus_tag="ROH59_000692"
     CDS             38401..39531
                     /locus_tag="ROH59_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDX4803214.1"
                     /translation="MSTLFTINACKSFGCRNLGQPTSTDYSWPDYRLGYPALHCRACG
                     SYPPLFDEQQFRDWLTVHLSTFATEKGHFCPVCYGTETICYGHNPQGSQRIQCRNCKK
                     VWTPKQYQKEITTPEIIETVALLVPFQGVSSGQKLYVLISFDALRGNILHLSTNYTQH
                     QAGESLHYRYRGNAEPELHDNNIVQRVDMREAQFLRRSQFDEIQYGSAALKRNAKGAI
                     LRPVITAHGHFRVLNILFPTVKTHVISHECFLRGAIITAWADLFRQQQGEIWFIEEEI
                     ADDTDNMPWRFQGKTYHGWWKNQWQLWVQGKNRKMVCALTGGKSSKAEMLSLATSRHF
                     IDWLHKQAVFTHSAPLSAGRVTQILLSLAQDYNNCASRLISD"
     gene            complement(39495..41927)
                     /gene="metL"
                     /locus_tag="ROH59_000693"
     CDS             complement(39495..41927)
                     /gene="metL"
                     /locus_tag="ROH59_000693"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HDX4803215.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADNLISAF
                     VSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPSAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(41930..43090)
                     /gene="metB"
                     /locus_tag="ROH59_000694"
     CDS             complement(41930..43090)
                     /gene="metB"
                     /locus_tag="ROH59_000694"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDX4803216.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQSDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            43367..43684
                     /gene="metJ"
                     /locus_tag="ROH59_000695"
     CDS             43367..43684
                     /gene="metJ"
                     /locus_tag="ROH59_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HDX4803217.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            43744..44352
                     /locus_tag="ROH59_000696"
     CDS             43744..44352
                     /locus_tag="ROH59_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HDX4803218.1"
                     /translation="MKIRLLIPGLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     SDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEDSKYIVRRVKGELNAEQQQK
                     LAQTAKRYLGKPYDSSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSNPLV
                     QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            complement(44413..44625)
                     /gene="rpmE"
                     /locus_tag="ROH59_000697"
     CDS             complement(44413..44625)
                     /gene="rpmE"
                     /locus_tag="ROH59_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDX4803219.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            44828..47026
                     /gene="priA"
                     /locus_tag="ROH59_000698"
     CDS             44828..47026
                     /gene="priA"
                     /locus_tag="ROH59_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDX4803220.1"
                     /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGSRVRVPFGKQQERIG
                     VVVSVSDVSELPLNELKAVVEVLDVEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQQHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDDFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILASPLADDKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIINGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            47182..48207
                     /gene="cytR"
                     /locus_tag="ROH59_000699"
     CDS             47182..48207
                     /gene="cytR"
                     /locus_tag="ROH59_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HDX4803221.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSRAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            48299..49258
                     /gene="ftsN"
                     /locus_tag="ROH59_000700"
     CDS             48299..49258
                     /gene="ftsN"
                     /locus_tag="ROH59_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HDX4803222.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            49351..49881
                     /gene="hslV"
                     /locus_tag="ROH59_000701"
     CDS             49351..49881
                     /gene="hslV"
                     /locus_tag="ROH59_000701"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HDX4803223.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            49891..51222
                     /gene="hslU"
                     /locus_tag="ROH59_000702"
     CDS             49891..51222
                     /gene="hslU"
                     /locus_tag="ROH59_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HDX4803224.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL"
     gene            51289..52215
                     /gene="menA"
                     /locus_tag="ROH59_000703"
     CDS             51289..52215
                     /gene="menA"
                     /locus_tag="ROH59_000703"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDX4803225.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGAVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            52308..52793
                     /gene="rraA"
                     /locus_tag="ROH59_000704"
     CDS             52308..52793
                     /gene="rraA"
                     /locus_tag="ROH59_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HDX4803226.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(52878..53123)
                     /gene="zapB"
                     /locus_tag="ROH59_000705"
     CDS             complement(52878..53123)
                     /gene="zapB"
                     /locus_tag="ROH59_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HDX4803227.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            53548..54393
                     /gene="glpF"
                     /locus_tag="ROH59_000706"
     CDS             53548..54393
                     /gene="glpF"
                     /locus_tag="ROH59_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HDX4803228.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            54416..55924
                     /gene="glpK"
                     /locus_tag="ROH59_000707"
     CDS             54416..55924
                     /gene="glpK"
                     /locus_tag="ROH59_000707"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDX4803229.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGMEEYIRNNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            56095..57105
                     /gene="glpX"
                     /locus_tag="ROH59_000708"
     CDS             56095..57105
                     /gene="glpX"
                     /locus_tag="ROH59_000708"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDX4803230.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            57202..57948
                     /gene="fpr"
                     /locus_tag="ROH59_000709"
     CDS             57202..57948
                     /gene="fpr"
                     /locus_tag="ROH59_000709"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HDX4803231.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIE
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPDCETLWMLATGTAIGPYLSILQLGKDLERFKNMVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESAVGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(57953..58381)
                     /gene="uspD"
                     /locus_tag="ROH59_000710"
     CDS             complement(57953..58381)
                     /gene="uspD"
                     /locus_tag="ROH59_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HDX4803232.1"
                     /translation="MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKLSADLLIVPFIDK"
     gene            complement(58408..58707)
                     /locus_tag="ROH59_000711"
     CDS             complement(58408..58707)
                     /locus_tag="ROH59_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HDX4803233.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAAASSADEGASVAYKIKDLEGQVELDAAFTFSCQAEMIIFELSLRSLA"
     gene            complement(58919..59359)
                     /locus_tag="ROH59_000712"
     CDS             complement(58919..59359)
                     /locus_tag="ROH59_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDX4803234.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFIPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN"
     gene            59460..60059
                     /locus_tag="ROH59_000713"
     CDS             59460..60059
                     /locus_tag="ROH59_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HDX4803235.1"
                     /translation="MKPGCTLFILLCSALTVTTTAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQITWLPIQGPEQKAAKAKAQAYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            60167..60934
                     /gene="tpiA"
                     /locus_tag="ROH59_000714"
     CDS             60167..60934
                     /gene="tpiA"
                     /locus_tag="ROH59_000714"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDX4803236.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(60989..61744)
                     /gene="cdh"
                     /locus_tag="ROH59_000715"
     CDS             complement(60989..61744)
                     /gene="cdh"
                     /locus_tag="ROH59_000715"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HDX4803237.1"
                     /translation="MKKAGLLFLVMIVIAVVTAGIGYWKLTGEESDTLRKIVLEQCLP
                     NQQENQNPSPCAEVKPNAGYVVLKDRHGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSQKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(61851..62840)
                     /gene="sbp"
                     /locus_tag="ROH59_000716"
     CDS             complement(61851..62840)
                     /gene="sbp"
                     /locus_tag="ROH59_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter
                     substrate-binding protein Sbp"
                     /protein_id="HDX4803238.1"
                     /translation="MKKWGVGLTFLLVATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGGTFDQISKR"
     gene            complement(63160..64122)
                     /gene="pfkA"
                     /locus_tag="ROH59_000717"
     CDS             complement(63160..64122)
                     /gene="pfkA"
                     /locus_tag="ROH59_000717"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDX4803239.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(64303..65205)
                     /gene="fieF"
                     /locus_tag="ROH59_000718"
     CDS             complement(64303..65205)
                     /gene="fieF"
                     /locus_tag="ROH59_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709720.2"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HDX4803240.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLVSPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(65442..65660)
                     /gene="ogrK"
                     /locus_tag="ROH59_000719"
     CDS             complement(65442..65660)
                     /gene="ogrK"
                     /locus_tag="ROH59_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage transcriptional regulator OgrK"
                     /protein_id="HDX4803241.1"
                     /translation="MFHCPLCQHAAHARTSRYITDTTKERYHQCQNVNCSATFITYES
                     VQRYIVKPGEIHAVRPHPLPSGQQIMWM"
     gene            complement(65742..66905)
                     /locus_tag="ROH59_000720"
     CDS             complement(65742..66905)
                     /locus_tag="ROH59_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HDX4803242.1"
                     /translation="MLDALTFDAGSTLTPDYMLMLDSRDITGNISDRLMSMTLTDNRG
                     FEADQLDIELNDADGQVGLPVRGAVLTVYIGWKGFALVCKGKFTVDEVEHRGAPDVVT
                     IRARSADFRGTLNSRREGSWHDTTLGAIVEAIASRNRLEASVAPSLAGIKIPHIDQSQ
                     ESDAKFLTRLAERNGGEVSVKMGKLLFLKAGQGVTASGKKIPQITITRSDGDRHHFAI
                     ADRGAYTGVTAKWLHTKDPKPQKQKVKLKRKKKEKHLRALEHPKAKPVTQKKAPKVPE
                     AREGEYMAGEADNVFALTTVYATKAQAMRAAQAKWDKLQRGVAEFSISLATGRADIYT
                     ETPVKVSGFKRVIDEQDWTITKVAHFLNNSGFTTSLELEVRLSDVEYETEGDE"
     gene            complement(66905..67384)
                     /locus_tag="ROH59_000721"
     CDS             complement(66905..67384)
                     /locus_tag="ROH59_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000978924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4803243.1"
                     /translation="MMLALGMFVFMRQTLPHQTMQRESDYRWPSNSRIGKRDAFQFLG
                     VGEENMTLAGVLYPELTGGKLTMTTLRLMAEEGRAWPLLDGTGMIYGMYVISRVSETG
                     SIFFADGTPRKIDFTLSLTRVDESLAALYGDIGKQAESLIGKAGSMATKFTGMTGAG"
     gene            complement(67399..69846)
                     /locus_tag="ROH59_000722"
     CDS             complement(67399..69846)
                     /locus_tag="ROH59_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDX4803244.1"
                     /translation="MSDNVKLQVLLRAVDQASRPFKSIRTASRSLSGDIRETQKSLRE
                     LNGQASRIEGFRKTSAQLAVTGHALEKARQEAEALATQFKNTERPTRAQAKVLESAKR
                     AAEDLQAKYNRLTDSVKRQQRELAAVGINTRNLAHDEQGLKNRISETTAQLNRQRDAL
                     ARVSAQQAKLNAVKQRYQAGKELAGTMASVGAAGVGIAAAGTMAGVKLLMPGYEFAQK
                     NSELQAVLGVAKDSAEMAALRKQARQLGDNTAASADDAAGAQIIIAKAGGDAAAIQAA
                     TPVTLNMALANQRSMEENAQLLLGTKASFQLSNDDVSHVGDVLSATMNKSAADFQGLS
                     DALTYLGPVAKTAGVSLEQAAAMTGVLHDNNIRGSMAGTGSSAVVTRLQAPTGKAWDA
                     LKELGVKTSDKKGNMRPLFTILKEIQASFDKHKLGTSQKGEYLKTIFGEEALKSANVL
                     LAAAASGKLDTLTATLKASDGKTEELVKIMQDNLGGDFKEFQSAYEAVGTDLFDQQEG
                     ALRKLTQTATKYVLKLDGWIQKNKSLASTIGLIVGGALALTGVIGAIGLVAWPVITGI
                     NAIIAAAGAMGAIFTTVGSAVMTAIGAISWPVVAVVAAIVAGALLIRKYWEPVSAFFG
                     GVVEGLKAAFAPVGELFTPLKPVFDWLGEKLQAAWQWFKNLIAPVKATQDTLNRCRDT
                     GVMFGQALADALMLPLNAFNKLRSGIDWVLEKLGVINKESGTLDQTATRTHAATYGTG
                     GYIPATSSYAGYQAYQPVTAPAGRSYVDQSKNEYHISLTGGTAPGTQLDRQLQDALEK
                     YERDKRARARASMMHDG"
     gene            complement(69839..69958)
                     /locus_tag="ROH59_000723"
     CDS             complement(69839..69958)
                     /locus_tag="ROH59_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HDX4803245.1"
                     /translation="MADVAVIFHWPPSELYPMSLTELITWREKALRRSGNTNE"
     gene            complement(69991..70266)
                     /locus_tag="ROH59_000724"
     CDS             complement(69991..70266)
                     /locus_tag="ROH59_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001719230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HDX4803246.1"
                     /translation="MNKENVITLDNPVKRGEQVIEQVTLMKPNAGTLRGVSLAAVANS
                     EVDALIKVLPRMTAPMLTEQEVAALELPDLVALAGKVVGFLSPNSVQ"
     gene            complement(70323..70841)
                     /locus_tag="ROH59_000725"
     CDS             complement(70323..70841)
                     /locus_tag="ROH59_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HDX4803247.1"
                     /translation="MAMPRKLKLMNVFLNGYSYQGVAKSVTLPKLTRKLENYRGAGMN
                     GSAPVDLGLDDDALSMEWSLGGFPDSVIWELYAATGVDAVPIRFAGSYQRDDTGETVA
                     VEVVMRGRQKEIDTGEGKQGEDTESKISVVCTYFRLTMDGKELVEIDTINMIEKVNGV
                     DRLEQHRRNIGL"
     gene            complement(70854..72044)
                     /locus_tag="ROH59_000726"
     CDS             complement(70854..72044)
                     /locus_tag="ROH59_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HDX4803248.1"
                     /translation="MSDYHHGVQVLEINDGTRVISTVSTAIVGMVCTASDADAEIFPL
                     NKPVLITNVQSAIAKAGKKGTLAASLQAIADQSKPVTVVVRVEDGTGEDEETKLAQTV
                     SNIIGTTDENGQYTGLKALLAAESVTGVKPRILGVPGLDTKEVAVALASVCQKLRAFG
                     YISAWGCKTISEVKAYRQNFSQRELMVIWPDFLAWDTVASTTATAYATARALGLRAKI
                     DQEQGWHKTLSNVGVNGVTGISASVFWDLQESGTDADLLNESGVTTLIRRDGFRFWGN
                     RTCSDDPLFLFENYTRTAQVLADTMAEAHMWAVDKPITATLIRDIVDGINAKFRELKT
                     NGYIVDATCWFSEESNDAETLKAGKLYIDYDYTPVPPLENLTLRQRITDKYLANLVTS
                     VNSN"
     gene            complement(72364..73263)
                     /locus_tag="ROH59_000727"
     CDS             complement(72364..73263)
                     /locus_tag="ROH59_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803249.1"
                     /translation="MSGIRITQAIDNNQILVNVNTFNYSVNPYPLKCPDPNCSAHLVY
                     VKSHIRRSFNKTLHIPAFFRLEKNFTHDKLCQYGTSGLNTIYASDSSHDISRALATGN
                     NIFRIHILDEDDISKLSRKAAAMQANPPSDTTDRVYVKRGRKAPYVKNMDSLREIYEY
                     GKAHPNKRNSIKIVTGTSTVTWSDFFYETTQLERLSTYLQKVKIAQVAVIMKVHVARI
                     PMAKFNYRHFIEGSPMRIKGGFNIYPTIQLGNVTPKLFPLSSIVMVLGKFTIPTNRKM
                     IMDPTFEREVRTIVSSEEQVLIL"
     gene            complement(73479..74006)
                     /locus_tag="ROH59_000728"
     CDS             complement(73479..74006)
                     /locus_tag="ROH59_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001762409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX4803250.1"
                     /translation="MQHLKNIKSGNPKTKEQYQLTKNFDVIWLWSEDGKNWYEEVKNF
                     QPDTIKIVYDANNIIVAITKDASTLNPEGYSVVEVPDITANRCADDSGKWMFRDGAVV
                     KRIYTADEQQQQAESQKAALLSEAESVILPLERAVRLNMATDEERSRLEAWERYSVLV
                     SRVDPANPEWPEMPQ"
     gene            complement(74010..76145)
                     /locus_tag="ROH59_000729"
     CDS             complement(74010..76145)
                     /locus_tag="ROH59_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4803251.1"
                     /translation="MSTKFRTVITTAGAAKLAAATAPGGRKVNITTMAVGDGGGKLPV
                     PDAGQTGLIHEVWRHALNKISQDKRNSNYIIAELVIPPEVGGFWMRELGLYDDAGTLI
                     AVANMAESYKPALAEGSGRSQTCRMVIIVSSVASVELTIDTTTVMATQDYVDDKIAEH
                     EQSRRHPDASLTAKGFTQLSSATNSTSETLAATPKAVKAAYDLANGKYTAQDATTARK
                     GLVQLSSATNSMSETLAATPKAVKTVMDETNKKAPLNSPALTGTPTTPTAPKGTNNTQ
                     IASTAYVMAAIAALVDSSPDALNTLNELAAALGNDPNFATTMTNALAGKQPKDATLTA
                     LAGLATAADRFPYFTGNDVASLATLTEVGRDILAKSTVAAVIEYLGLQETVNRAGNAV
                     QKNGDTLSGGLTFENDSILAWIRNTDWAKIGFKNDADGDTDSYMWFETGDNGNEYFKW
                     RSKQSTTTKDLMNLKWDALSVLVKALFSSEVKISTVNALRIFNSSFGAIFRRSEECLH
                     IIPTRENEGENGDIGPLRPFTLNLRTGRISMGHGLDVTGDIFANRFAINSSTGMWINM
                     RDQNVILGRNAVSTDGAQALLRQDHADRKFMIGGLGNKQFGIYMINNSRTANGTDGQA
                     YMDNNGNWLCGAQIIPGNYGNFDSRYVRDVRLGTRVVQTMQKGVMYEKSGHAITGLGI
                     IGSVDGDDPAVFRPIQKYINGTWYNVAQV"
     gene            complement(76156..76686)
                     /locus_tag="ROH59_000730"
     CDS             complement(76156..76686)
                     /locus_tag="ROH59_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001285325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HDX4803252.1"
                     /translation="MSDSRLLPTGSSPLEVAAAKACAEIEKTPVSIRELWNPDTCPAN
                     LLPWLAWAFSVDRWDEKWPEATKRAVIRDAYFIHCHKGTIGAIRRVAEPLGYLINVTE
                     WWENSDPPGTFRLDIGVLESGITEAMYQEMERLIADAKPASRHLIGLNITRDIPGYLF
                     AGGVAYDGDVITVYPG"
     gene            complement(76679..77587)
                     /locus_tag="ROH59_000731"
     CDS             complement(76679..77587)
                     /locus_tag="ROH59_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001121472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HDX4803253.1"
                     /translation="MPIIDLNQLPAPDVVEELDFETILAERKATLISLYPEDQQEAVA
                     RTLTLESEPLVKLLEENAYRELIWRQRVNEAARAVMLACAAGNDLDVIGANYNTTRLI
                     ITPADDSTIPPTPAVMESDTDYRLRIQQAFEGLSVAGSVGAYQYHGRSADGRVADISV
                     TSPSPACVTISVLSRENNGVASEDLLAVVRNALNGEDVRPVADRVTVQSAAIVEYQIN
                     ATLYLYPGPESEPIRAAAVKKLEAYITAQHRLGRDIRLSAIYAALHVEGVQRVELAAP
                     LADIVLNSTQASFCTEYRVVTGGSDE"
     gene            complement(77592..77939)
                     /locus_tag="ROH59_000732"
     CDS             complement(77592..77939)
                     /locus_tag="ROH59_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HDX4803254.1"
                     /translation="MTARYLGMNRSDGLTVTDLEHISQSIGDILRTPVGSRVMRRDYG
                     SLLASMIDQPQTPALELQIKVACYMAVLKWEPRVTLSSVTTARSFDGRMTVTLTGQHN
                     DTGQPLSLTIPVS"
     gene            complement(77936..78571)
                     /locus_tag="ROH59_000733"
     CDS             complement(77936..78571)
                     /locus_tag="ROH59_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HDX4803255.1"
                     /translation="MNTLANIQELARALRNMIRTGLVVETDLNAGRCRVQTGGMCTDW
                     LQWLTQRAGRSRTWWAPSVGEQVLILAVGGELDTAFVLPGIYSGDNPAPSASADALHI
                     RFSDGAVIEYEPETSALTVSGIKTASVTASDSVTATVPVVTVKASTRVTLDTPEVVCT
                     NKLTTGTLEVQKGGTMRGNIEHTGGELSSNGKVLHTHKHPGDSGGTTGSPL"
     gene            complement(78638..79090)
                     /locus_tag="ROH59_000734"
     CDS             complement(78638..79090)
                     /locus_tag="ROH59_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HDX4803256.1"
                     /translation="MNEFKRFEDRLTGLIESLSPSGRRRLSAELAKRLRQSQQRRVMA
                     QKAPDGTPYAPRQQQSARKKTGRVKRKMFAKLITSRFLHIRASPEQASMEFYGGKSPK
                     IASVHQFGLSEENRKDGKKIDYPARPLLGFTGEDVQMIEEIILAHLDR"
     gene            complement(79083..79550)
                     /locus_tag="ROH59_000735"
     CDS             complement(79083..79550)
                     /locus_tag="ROH59_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001406878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4803257.1"
                     /translation="MLKPDSLRRALTDAVTVLKTSPEMLRIFVDNGSIASTLATSLSF
                     EKRYTLNVIVTDFTGDFDLLIVPVLAWLRENQPDIMTTDEGQKKGFTFYADINNDSSF
                     DISISLMLTERTLVSEVDGALHVKNIPEPPPPEPVTRPMELYINGELVSKWDE"
     gene            complement(79513..79671)
                     /locus_tag="ROH59_000736"
     CDS             complement(79513..79671)
                     /locus_tag="ROH59_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein"
                     /protein_id="HDX4803258.1"
                     /translation="MPGSDPETNGDLSADIRQLENALARCASQVKMIKHCQDENDAQT
                     RQPAQGAD"
     gene            complement(79658..80083)
                     /locus_tag="ROH59_000737"
     CDS             complement(79658..80083)
                     /locus_tag="ROH59_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001585210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HDX4803259.1"
                     /translation="MSKLMIVLVVLLSLAVAGLFLAKHENASLRASLDRVNNVASEQQ
                     TTITMLKNQLHVALTRADKNELAQVALRQELENAAKREAQREKTITRLLNENEDFRRW
                     YGAGLPDAVRRLHQRPACTDASDCPQRLPESEPLPDAGQ"
     gene            complement(80071..80496)
                     /locus_tag="ROH59_000738"
     CDS             complement(80071..80496)
                     /locus_tag="ROH59_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysA"
                     /protein_id="HDX4803260.1"
                     /translation="MKKLSLSLMLHVSLALMLALSLIYPQSVAVNFVAAWAILATVIC
                     VVAGGVGVYATEYALERYGWELPPESLAVKIVMSLFLQPVPWCRRAAALVVMVATFIS
                     LVAAGWIFTALIYLVASVFFRLIRTACRQRLEGREPCQS"
     gene            complement(80511..81008)
                     /locus_tag="ROH59_000739"
     CDS             complement(80511..81008)
                     /locus_tag="ROH59_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 104 protein"
                     /protein_id="HDX4803261.1"
                     /translation="MPVINTHQNIAAFLDMLAVSEGTANHPLTKNRGYDVIVTGLDGK
                     PEIFTDYSDHPFAHGRPAKVFNRRGEKSTASGRYQQLYLFWPHYRKQLALPDFSPLSQ
                     DRLAIQLIRERGALDDIRAGRIERAISRCRNIWASLPGAGYGQREHSLEKLVTVWRTA
                     GGVPA"
     gene            complement(81008..81289)
                     /locus_tag="ROH59_000740"
     CDS             complement(81008..81289)
                     /locus_tag="ROH59_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDX4803262.1"
                     /translation="MTAEEKSVLSLFMIGVLIVVGKVLAGGEPITPRLFIGRMLLGGF
                     VSMVAGVVLVQFPDLSLPAVCGIGSMLGIAGYQVIEIAIQRRFKGRGKQ"
     gene            complement(81293..81496)
                     /locus_tag="ROH59_000741"
     CDS             complement(81293..81496)
                     /locus_tag="ROH59_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HDX4803263.1"
                     /translation="MKTFALQGDTLDAICVRYYGRTEGVVEAVLAANPGLAELGAVLP
                     HGTAVELPDVQTAPVAETVNLWE"
     gene            complement(81496..82005)
                     /locus_tag="ROH59_000742"
     CDS             complement(81496..82005)
                     /locus_tag="ROH59_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HDX4803264.1"
                     /translation="MMTLIIPRKEAPVSGEGTVVIPQPAGDEPVIKNTFFFPDIDPKR
                     VRERMRLEQTVAPARLREAIKSGMAETNAELYEYREQKIAAGFTRLADVPADDIDGES
                     IKVFYYERAVCAMATASLYERYRGVDASAKGDKKADSIDSTIDELWRDMRWAVARIQD
                     KPRCIVSQI"
     gene            complement(82105..82848)
                     /locus_tag="ROH59_000743"
     CDS             complement(82105..82848)
                     /locus_tag="ROH59_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HDX4803265.1"
                     /translation="MTSPAQRHMMRVSAAMTAQREAAPLRHATVYEQMLVKLAADQRT
                     LKAIYSKELKAAKKRELLPFWLPWVNGVLEQGKGAQDDILMTVMLWRLDTGDIAGALE
                     IARYALKYGLTMPGKHRRTPPYMFTEEVALAAMRAHAAGESVDTRLLTETLELTATAD
                     MPDEVRAKLHKITGLFLRDGGDAAGALAHLQRATQLDCQAGVKKEIERLERELKPKPE
                     PQPKAATRTPRKTRSVTPAKRGRPKKKAS"
     gene            complement(82852..83925)
                     /locus_tag="ROH59_000744"
     CDS             complement(82852..83925)
                     /locus_tag="ROH59_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HDX4803266.1"
                     /translation="MRQETRFKFNAYLSRVAELNGIDAGDVSKKFTVEPSVTQTLMNT
                     MQESSDFLTRINIVPVSEMKGEKIGIGVTGSIASTTDTAGGTERQPKDFSKLASSKYE
                     CDQINFDFYIRYKTLDLWARYQDFQLRVRNAIIKRQSLDFIMAGFNGVRRAETSDRSS
                     NQMLQDVAVGWLQKYRNEAPARVMSKVTDEEGHTTSEVIRVGKGGDYASLDALVMDAT
                     NNLIEPWYQEDPDLVVIVGRQLLADKYFPIVNKEQDNSEMLAADVIISQKRIGNLPAV
                     RVPYFPADAMLITKLENLSIYYMDDSHRRVIVENPKLDRVENYESMNIDYVVEDYAAG
                     CLVEKIKVGDFSTPAKATAEPGA"
     gene            complement(83984..>84598)
                     /locus_tag="ROH59_000745"
     CDS             complement(83984..>84598)
                     /locus_tag="ROH59_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HDX4803267.1"
                     /translation="KWALFAKITPTDDLIAMNKAAQKVYTSMEIQPNFANTGKCYLVG
                     LAVTDDPASLGTEYLEFCRTAKHNPLNRFKLSPENLISVATPVELEFEDLPETVFTAL
                     TEKVKSIFGRKQASDDARLNDVHEAVTAVAEHVQEKLSATEQRLAEMETAFSALKQDV
                     TDRADETSQAFTRLKNSLDHTESLTQQRRSKATGGGGDALMTNC"
BASE COUNT        20237 a        23116 c        21416 g        19829 t
ORIGIN      
        1 gagacttggt attcattttt cgtcttgcga cgtcaagaat ccgtatcttc gagtgcccac
       61 acagattgtc tgataaattg ttaaagagca gtgccgcttc gcttttctca gcggcgcggg
      121 gtatacataa tacgctttcc cgctacagag tcaagcattt ttttgctttc ctctgttgag
      181 attctcagga gaaccccgct gacccggcgg cgtgtttgcc gttgttccgt gtcagtggtg
      241 gcgcattata gggagttatt ccggcctgac aagaggaaat ttaaaataat tttctgaccg
      301 cgcaacattc aaccaaatca atctaaaact gccagttttt cgagcgtttc gaagccgtaa
      361 cgctgtaaaa cgggcaataa ttgttcagct tctggcgtca ttgccataca aaatgcaata
      421 ttcgcatcgg cagattttgc atccggggct tcatgctcta acaaccaggc cgttcggcga
      481 gcaatcgctg cgccagaatc caccagccgg gttccctctg gcagcacttg taatagttct
      541 tcttgtagta gagggaaatg ggtgcaaccc aatacaactg tatctggcgg ctctttcatt
      601 cttaaccacg ggcgtaggat acgttttagc gcatccagag aaacatcttc gccatgcagc
      661 ttcgcttcag ccaactcaac catctctgcc gagcccagca tttctatctg gcattcatta
      721 gcgaaacgcg cgatcagctc atgagtataa gaacgtttaa cagttccgcg ggttgccagt
      781 aatccgacaa tgccatttgc cgtcagacgt gcagcaggtt taatcgccgg cacgacacca
      841 acaaccggga agtcgaactt ttcgcgtaat gcaggaagtg aaacggtact ggcggtgttg
      901 caagcgacca cagccagcgc aaggggataa cgttcttgca ctgcggtgac aatttccacc
      961 actcgctcaa caataaacac ttcgcttttt tcgccatacg ggaaagcgac gttatcgaaa
     1021 gcataaatgt aatggagatc cggcaagaga tgccggatct cgtcatagac cgacaaccca
     1081 ccgacgccgg agtcaaacac cagcacggtg ggacgtggtt cagaaggtgt agctgccaga
     1141 caaggtgtat tcccgtcctg cagtttggta gccatagact gtctcgtaat ctttgtcgaa
     1201 caggttggct attttaccac gaactgtcag gtgagaggtg accggatatg caacagcaag
     1261 atcccacaag ctcaccccgc ccattttcac tgtttgatac ggataagagg agtaatcctt
     1321 atcataacga gaacctaagt actgataagt aatcccccag tcgaagtcat acaactgcca
     1381 gtcgagctgg tatttcacct gctgtttagc acggcgtaac aacggcgtgt cagtaatcgc
     1441 attgcgcgca tcaacataat cataactcac agtatgcgtc agtggtccgg tatcaaaatt
     1501 ggcggtcgcc tcgacaccct taatccgcgc tttcccttcg ttgtaatatt tcagggtgtg
     1561 atcatcataa tcgatcaagt cactgacatc gttacgatat ccggaaatac gccagttcac
     1621 cccagcagtt aagccttcaa acgcgccttc ccactgtttg cttttctcag ggtcgagatt
     1681 cggatttccg tagaaaccat acagttgtcc aagatttggt gccttataag atgtcccgta
     1741 ggaagcaata aagcgataac cttcgataaa ttcccaaccg gcgctggttt gccaggtgcc
     1801 atgacgacca aactgtgagt tatcgtcgct acgtgctgcg ccttcaaagg taaaatcgcc
     1861 aacttgttgc agcccggtca gatagatgcc ggtattacgt tgatcatatc catcctcaac
     1921 ataagctgtg cccggtgccg tgctctgctt ctgccagtca acacccgcac caatattacc
     1981 gtggccaatg atgatgttgt ttgcccactg gacggtgtac tgtttcatct catcgagcgt
     2041 cgcggatgaa tcataacgac cataatgcgg atcgtagttg taatctttgc tatggctgta
     2101 gctggtaatc agttgtgatt taatcagttc accgttatag cgcagtccgg catcccaact
     2161 ttggctatag agtttacggg tatcgaccag tggcgagccg ggagaataat atgcgtcata
     2221 attggtacga ttatcatagc catagccgcg cacaaagccg ctccagacat cagtaaaatt
     2281 atgctccagc gcgccataaa gcgttttact taaaaaacca tcgttatctg gctgcgcttg
     2341 cgttccggta ttaccatagg cgacaacatc ataaccatga gtatgggcat aatcgcccaa
     2401 cagcgttacc cgtgtcttat cccccagttg ttgctgtgta gagacatcat agttctgata
     2461 actattgctt ccccaccctg ctgaaatttc cgttccgggg tgatcgcgcg tcgtgatgat
     2521 attcacgacc ccgcctattg catctgaacc ataaacagcg gagcgcggcc cacggatata
     2581 ttcaacacgc tggacaagcg caatagggaa ctgactaaga tcagcagaac cactcacccc
     2641 cgccaaattc aggcggacgc catcaattaa caccaacaca tgactggcat ttgtaccgcg
     2701 aataaaaata gatgagagct gacctgaacc gccgttttgg gtgatatcca cgcccggaag
     2761 acggcgcagc acatcattga ccgaggtcga ctgccagcgg tcgatatcct gacgcgtcac
     2821 aacagtagtt ggcgcaagca cagtgctgcg cggttgttca aaacggttag cagtaacgac
     2881 gagagtatcc gggctggtat cctgtgccca agcggaaaat gccgtgacgg aacacgccgt
     2941 cagcagcgaa gcttttttaa tcattgtaaa gcatccacaa tagaagaagg atgccgcagg
     3001 tttcatcaat attacgcgat gatgagaacc agatgcgacg ttggccggca ggtcttcggg
     3061 cttggagggg tatctaagat actaagagat gatgacttcc caccggatgg cagtgtccgc
     3121 ataacgcaat catcgcacct ttccttaccg ctgcgcgtca gctccagatt cgcactggat
     3181 tccctattaa ctcacaggac cggcaagtgg atgctacagg ttgtaacaag ttactgtcca
     3241 gacgtagctc acaaatagga attcatcaag atctggacat ctgatgagca atccctacaa
     3301 tcgccgcgta ctttaatttt tcaggataca tcatgacccc cgaacacctt ccaacagaac
     3361 agtatgaagc gcagttagcc gaaaaagtgg tacgtttgca aagtatgatg gcaccgtttt
     3421 ctgacctggt tccggaagtg tttcgctcgc cggtcagtca ttatcggatg cgtgcggagt
     3481 tccgcatctg gcacgatggc gatgacctgt accacatcat tttcgatcaa caaaccaaaa
     3541 gtcgtatccg tgtggatagc ttccccgccg ccagtgaact tatcaaccag ttgatgacgg
     3601 cgatgattgc gggtgtgcgt aataatccca ttctgcgcca caagttgttc cagattgatt
     3661 acctcactac gctaagcaat caagcggttg tttccttgct gtaccataaa aagctggatg
     3721 atgagtggtg tcagcaggcg gaagccctgc gcgatgcact gcgcgcgcag aatctgaatg
     3781 tgcatctgat tggtcgggca acgaaaacca aaatcgcgct ggatcaggat tacatcgacg
     3841 aacgtctgcc gatcgcgggg aaagagatga tctaccgtca ggtagaaaac agctttaccc
     3901 aaccgaacgc ggcgatgaat attcagatgc tggaatgggc gctggacgta accaaaggct
     3961 caaaaggcga tttactggag ctatactgcg gcaacggtaa cttttcatta gcgctggcac
     4021 gcaattttga tcgggtatta gccaccgaaa tcgccaagcc gtcagtcgcc gccgcgcaat
     4081 acaacattgc cgctaaccat attgataacg tacaaattat tcgtatggcg gcagaagaat
     4141 ttactcaggc gatgaatggt gtgcgcgagt ttaaccgcct gcaaggaatc gacttaaaga
     4201 gttatcagtg cgaaaccatt tttgtcgacc caccgcgcag cggtctggac agtgaaaccg
     4261 agaaaatggt gcaggcgtat ccacgtattc tgtatatctc ctgcaatccg gaaacgttat
     4321 gcaagaatct ggaaacatta agccagacgc acaaggtcga acgtctggct ctatttgatc
     4381 agttccccta cacgcaccat atggagtgcg gcgtattact gaccgcgaag taaaacccat
     4441 gtcggatgcg cctgcatccg gcatgatgct gattactcag caacgtcctg cttacggtta
     4501 cgcatcttcg cgccaatcca gaacaccata atgacggaca gtactgccgg gaagaagttg
     4561 gaaccgatat ccggatattc cgcacgaact accgtgctgt acagcagtac gccgagaata
     4621 aaacaagcag ctgccagacc cggcaagcct accggcatag tgcgattaag ataacgttga
     4681 tgcaggcagt aaactgtcaa caccagggaa ataatcggga atacagaaaa tggtacaatg
     4741 gagctaaaca gcgctgcgaa agtaccatta atcgataagc cagccactag cgccagcagc
     4801 agcgtacctc tatcttgatt tgcttgtttc attactcgtc cttcacattt cccggaataa
     4861 ttgcggtttt ctcttgttca cggcgatacc agtaataagc ccctttcgaa atcattcgca
     4921 gctgcagtac cagtcgctct tctaattgcc gacgttgctc gacgccgaca tccaacgcct
     4981 cggcccccgc actgaagaca atcgtcacca ttgcttcggc ttgcgcttca gtaaacgcac
     5041 gcggcatatg gttttcgagt tccagatagt ccgcaagttc cgcaatgaag tgctgaattt
     5101 cacgcgcaac ggcggcacga aacgcagcgg aggtgccgga gcgttcccgc aataataacc
     5161 ggaaggcgtt aggattatta ccgatgaact ccataaatgt ggagaccgag gtgcggatca
     5221 cactcccgcc tttggcgata cgctgacgcg cctgacgcat gagttggcgt agcattaaac
     5281 cgctctcatc aaccatggtc agacccagtt cgtctacgtc gcggaaatgc cgataaaaag
     5341 aggtgggagc aatgcctgct tctcgtgcca cttcacgcaa actcaggctg gcgaagctgc
     5401 gttcagcact taattggcta aatgcggctt ccaccagcga acggcgggtt ttttcttttt
     5461 gttgcgctct tacgcccatc acgatgtctg aatccttgcc aaaagtactg ctggcactat
     5521 accagagaat gaacatactg gattgctcca gtgttgtgaa tgaacggtaa cgcaataaaa
     5581 catatttact gcaattcttt ggccggttct tttacgtaca acaacgccag catcgacagc
     5641 aacgtgcctc cacccagata ccacgccgga gccgtcagac tatccagcaa cacgatggat
     5701 tgcgtagcga aatattgagc aaaaccgcca aagattgcca caccaatgct ataaaccagc
     5761 gcaaaaccca atgcccgaat ccgtttcggc aacagttcag agatcaacaa catcactggc
     5821 acaccgccaa gcgtggtaaa gctgaccatc acgaaaacca ccgtcagcaa catgccaggg
     5881 cttgggtaat tcaccaacag ccagaatgac ggccagctac agagaagcac catcacacgg
     5941 gagattaaaa tcagcttttt acgcccgacc gaatcgcaca acatccccac aagcagcgca
     6001 cccacaaacg taacaacgcc cgccagtaac atcgctgcat gagaataatg ttgaggcatc
     6061 gccagatact tcgccgccca ggtgccgtaa taaaagaggg agatataggt tgcgaccgtg
     6121 ctaccaatag cgagtaaaac gccattaacg atagtcgcct tatgttgcag gagcagagaa
     6181 aacgcgcttt cgctggtagc agctttttta ttgcgcacag gctcaggtac gtcattttcc
     6241 aggctcagac gcaaccagca accgataggt gctaataaca caccaataaa aaacggcaca
     6301 cgccagcccc attctgccat tacggtttct gaacctgtgg cgaacggtag ccatgcgctt
     6361 aaacctaaag cgacaacacc gccaaaagtt gttgccaggc cttgagtcgc cagtgaccaa
     6421 ctgctgtaaa agccacgacg atttgccgga gctgactcca ccagtagcga cattgaagcc
     6481 ccgacttcac cacctgccgc aacgccctga atcaaacgcg ccagcaccag cgttgcggtt
     6541 ccccaatagc ccgccgtttc atacgtcggt gcgatgccga tcatcagcgt accgaggctc
     6601 atcagagcaa tagtgaacac catcgccggt ttacgcccga agcgatcggc ccaggcacca
     6661 acgataatcc caccgagcgg acgcataaaa aagctcacac caaacgttgc aaatgccagt
     6721 aacagcgcga cgttatgatc ggcactgggt gggaagaaaa gcgtactgat atagaccaca
     6781 aaaaagttgt aaacgccaaa atcaaaaaat tcgagcgcat tgccaaacgc cgaggcaaag
     6841 atcacccgcc tgccgctggg ctttttcttc acactcacgg tttcatttac gatcgccgtc
     6901 attccatgtt ccttgccaaa aagtgttgtt gtgtgttgtt ttatttattg cagccaggct
     6961 tcaaccagtg cgccccagta gctgcttgcc gggaccaggc ttgcatcgtt aaagtcgtaa
     7021 ccggggttat gcaccatgca ggaaccttcc ccgacatcgc cattaccgaa taacaggaaa
     7081 ccgcctttgg gttgggcctc cagcatgaaa gagaaatctt cactgcccat caggggtttg
     7141 atgccaaact cagcccgatc ttcaccaaat gttttgcacg ccacctgcca ggcgaagcgc
     7201 gccatctcct cgtcatttac taataccggt gtaccgttaa catgcgtaac ctcagccgta
     7261 gcgccaaagc tggcagcctg ggtttgtgca agagcaggaa tacgggtcag aagaagttgt
     7321 cgggtatcgc ggctaagaga gcggacactg attttcatct cagcactgtc aggaatgacg
     7381 ttagccgcct cacccgcaac aatgctgccg acggtaatta ccgccgcttc cagcggatcg
     7441 acattgcgcg acacaatgct ttgtaatgcg gtggtgatat gtgcggcaac cagcactgga
     7501 tcgatggctt tgtgcgggat cgcaccgtgt ccgccacaac cacgaaccgt aatatggaac
     7561 tgatccattg acgccatcag cgccccaggc tggaagaaaa acttgccgac cggcaaaccc
     7621 ggcatgttgt gcatcccgaa aatgacatcg caggggaaac gatcaaaaag cccctcttta
     7681 accatgatct caccgccgtt aatcatctct tccgctggct ggaagataag gcgtaacgtg
     7741 ccgttaaaac ggcgggtttc ggcaaaataa cgcgcggccc ccagcagtat ggtggtatgc
     7801 ccgtcatgcc cgcaggcgtg cattaaacca ggatgtttac tggcccaggg cttgccacta
     7861 ttttcataaa tcggcaacgc atccatatcc gcccgcaggc caatactttt ctctccgtcg
     7921 cccactttta acgtggctac cacgccggtt gtcgccagcc cttgctcaac ctcatagccc
     7981 cactggcgca gcttttccgc aaccaaagca ctggttttaa attcttgtaa tcccagctcc
     8041 gggttttcgt ggatctgatg gcggatctcg cgaagttctt cctcaaaccc acgaatatag
     8101 tgttcgatca tcggctattc ctttattcac ttataaacag gctaattaac ggattttatt
     8161 gatggtataa atacaaataa cccatcaata taaaatattt atacatttgt tttataagaa
     8221 gatttcataa agacaataac aaaaaagcac gcttcggcaa gataaaacta tcagccataa
     8281 gaaaaagcga ttaatagtga ataaataaaa taagaaggag gaagacaaag caaaggccgc
     8341 tcacgatata gccagataaa tgacggggat caattggctt acccgcgata aaatgttacc
     8401 attctgttgc ttttatgtat aagaacaggt aagccctacc atgccacatt cctacgatta
     8461 cgatgccata gtaataggtt ccggccccgg cggcgaaggc gctgcgatgg gcctggttaa
     8521 gcaaggtgcg cgcgtcgcag ttatcgagcg ttatcaaaat gttggcggcg gttgcaccca
     8581 ctggggcacc atcccgtcga aagctctccg tcacgccgtc agccgcatta tagaattcaa
     8641 tcaaaaccca ctatacagcg accattcccg actgctccgc tcttcttttg ccgatatcct
     8701 taaccatgcc gataacgtga ttaatcaaca aacgcgcatg cgtcagggat tttacgaacg
     8761 taatcactgt gaaatattgc aggggaacgc tcgctttgtt gatgagcata cgttggcgct
     8821 ggattgcccg gacggcagcg tcgaaacact aactgctgaa aaatttgtta ttgcctgcgg
     8881 ttctcgtcca tatcatccaa cagatgttga tttcacccat ccacgcattt atgacagcga
     8941 ctcaattctt agcatgcacc acgaaccgcg ccatgtactt atttacggtg ctggagtgat
     9001 cggctgtgaa tatgcgtcga tcttccgcgg tatggatgta aaagtggatc tgatcaacac
     9061 ccgcgatcgc ctgctggcat ttctcgatca agagatgtca gattctctct cctatcactt
     9121 ctggaacagt ggcgtagtga ttcgtcacaa cgaagagtac gagaagatcg aaggctgtga
     9181 tgacggtgtg atcatgcatc tgaagtcggg taaaaaactg aaagctgact gtctgctcta
     9241 tgccaacggt cgcaccggta ataccgattc gctggcgtta cagaacattg ggctggaaac
     9301 tgacagtcgc ggacagctga aggtcaacag catgtatcag accgcacagc cgcacgttta
     9361 cgcggtgggc gacgtgattg gttatccgag cctggcgtcg gcagcctatg accaggggcg
     9421 cattgccgcg caggcgctgg tgaaaggtga agccaccgca catctgattg aagatatccc
     9481 taccggcatt tacaccatcc cggaaatcag ctctgtaggc aaaaccgaac agcagctgac
     9541 cgcgatgaaa gtgccatatg aagtaggccg cgcccagttt aaacatctgg cacgtgcaca
     9601 aatcgtcggc atgaacgtgg gcacgctgaa aattttgttc catcgggaaa caaaagagat
     9661 tctgggtatt cactgctttg gcgagcgcgc tgccgaaatt attcatatcg gtcaggcgat
     9721 tatggaacag aaaggtggcg gcaacactat tgagtacttc gtcaacacca cctttaacta
     9781 cccgacgatg gcggaagcct atcgggtagc tgcgctaaat ggcttaaacc gcctgtttta
     9841 acactttatc gaaatggcca tccattcttg cgcggatggc ctctgccagc tgctcatagc
     9901 ggctgcgcag cggtgagcca ggacgataaa ccaggccaat agtgcggcgt ggttccggct
     9961 taatgcacgg cagataaaca accccatcgc gtttgcgttc cggcggcaca gccagcgcag
    10021 gcagtaaagt gatcccgcta cctgccgcca ccatgttgcg cagagtttcc aggctggtcg
    10081 cgcggaagtg tgtatcttca tccgccccgg cttcaaaaca gaaacccatt gcctgatcgc
    10141 gcaaacagtg accatcttcc agcatcagca gtttttcccc tgccagatcg gccatcggta
    10201 cgcattcgcg gttcgcccac gggtggtctt catagatagc cagcaacatt ggctcatcaa
    10261 acaacggcac ttcaatgaat gcttcgctct ctttcaccag cgcgaggatc acgcaatcga
    10321 gtttgccgct gtccagttgc gccagtaact ggtgggtctg tgcttcatgc agatacattt
    10381 ccagctttgg aaaggtctgg tgcagcatcg ggataatatg cggtagcagg tacggtccaa
    10441 ccgtgggaat caaaccaata tgcagcggtc cggacatcgt ctcgccctgc tggcttgcca
    10501 tctctttaag gactttcacc tcacgcagca cggtacgcgc ctgatccacc agcagcattc
    10561 ccgcctgggt gaataacact ttacggctgg tccgctccag caacatcacg cccagctcat
    10621 cttccagctt acgaatttgc ccgctaagcg tcggctggct aacgtggcag gaatctgccg
    10681 cacgccgaaa atggcggtgt tcagccaatg ccaccaggta ctcaagatca cgaatattca
    10741 ttatccatcc tccatcgcca cgatagttca tggcgatagg tagaatagca atgaacgatt
    10801 atccctatca agcattctga ctgataattg ctcacagaaa cggagcggca cctcttttaa
    10861 cccttgaagt cacagcccgt ttcgagagtt tctcagctcg aataactaaa gccaacgtga
    10921 acttttgcgg atctccagga tccgcttttt tttgccataa aaaagcccag cgataagcca
    10981 ggctcaaatt tatacatata aatgttctta ccccaaccgc gcctgcgcaa aagcaatcgc
    11041 ctgcgccacc tgttgcggtg agacaccgcc ttttgccgca cgcttgtcga ggcacgattg
    11101 cagcgacaga atcggataga catcttcgcc aatcaccagg ctgaatttct gcaactcact
    11161 gagtggcaga tcttccagcg gtttgccctg acgaatggct tccaccaccg cttcacccac
    11221 aatatggtgc gcctcgcgga acggtacgcc tttcgccacc agataatccg ccagttcagt
    11281 agcgttggag taaccctgct gcgccgcttc ctggcaacgc ggacgtttca cctgaatgcc
    11341 gtccagcacc agcgccgcca tatgcaggca gtccagccag gtatcgagcg cgtcgaacag
    11401 accttctttg tcttcctgca tatctttgtt gtaagccagc ggcaaacctt tcagcgtcat
    11461 catcatgccg gttaacgccc cctgcacccg accgcattta ccgcgaatca gctccagcgc
    11521 atccgggttt ttcttctgcg gcattaatga tgaaccggaa gtcacacggt cagaaagctc
    11581 cacaaacccc gcttcgccgg tgttaaagaa aatcagatct tcagcaaaac gcgacagatg
    11641 caccatgccg atagcggcag cagaaagcag ttccaacaca tggtcacggt cagaaacgct
    11701 gtcgagactg ttacgggtcg ccgaagcaaa gcccagccaa cctgctaact gttcacggtc
    11761 gatttcatag gccgttcctg ccagtgcgcc acagcctagc gggctgacat ccagacgctt
    11821 aagcgcatcc tgcaaacggc tttcatcacg cgccagcatc tcaacgtagg ccaggcacca
    11881 gtgcgcgaac gtcaccggct gggcgcgttg caggtgggtg taacccggca tcaccgcgtc
    11941 ctgattgttc tgcgcggtct cgaccagagc ggattgtaac tgccggttag ccgtcagcaa
    12001 ctcgctaacg gtatctttgc accacagttt caggtcagtt gctacctgat cattacggct
    12061 acgcccggta tgcaattttt tgcctaactg acccactttg tcgatcagtt tgccttccac
    12121 ccagctatgg atatcttcgg cgtcgctttc aaggatttgt tgtggcctgg cgcgaacatc
    12181 ttccagcagc acgttcagcg cctcttccag ttgcgcctgc tcttctgcgg ttaacacgcc
    12241 gaccgttacc agggctttgg accaggccac agagccaaca atatcctgct ccgccagacg
    12301 gtaatcaaag cgcagtgagt cgttgaattg tttgaaccgt tgatctgctg cctgggtaaa
    12361 acgcccgccc caaagtgcca taactctgtt tccttatttt gaaattcaat gccggaaagc
    12421 tgcgcctccg gccaacaaaa cttaagctaa aatccgcgtc cccatcggca taccgttaaa
    12481 cagtgccgga agctgttccg catgacgcca ggaggcgata tctaccggac ggcccaacgt
    12541 gcgcgcagca tccagcgccg cgttcacttt cacaatcatg ccgtcagtaa taatgccctg
    12601 ctcaatcagt tgttctgctt tcgcggcggt catttcggca atacgttgcc ctttgccgtc
    12661 gagaatgccg ctgacgtcag agagcaaaat cagatccgcg cccagcgttg ccgccagcgc
    12721 cgtcgccgcc tggtcggcat tgacgttcat cagttgccct tcgtctgtta cgccaatgga
    12781 gctgaccacc ggcagataac cgttctccag caaactgttg ataagcttag gcgaacctgg
    12841 ctgcgccagt ccaacatggc ctaactcttc atcaagctgg gtcactttga tgctgtcgcc
    12901 gtcaccgaga aacaaaccta cggccgcaat ctgatgtttc ttcgcccatg ccagcagggt
    12961 tttatttgcc gttcccgcca gtgctccggt gataatgtct atctgatccg caggcgtcac
    13021 ccgcaggcca tttttctttt tcaccggcag attcagccct ttcatcagct catccaccac
    13081 acaaccgccg ccgtgcacaa tcaccagcgg acgctgatgt gactcgcgat aattcaccag
    13141 tgcgctaaac agacgttcca gcgcctcttc actatccagc agtacgccac ccagtttgat
    13201 aattaatgga ttcatcattg cacccttaaa taagagactg cgtttccgca tagccgaaac
    13261 gaatattggc gcactgcacc gcttgtgccg ccgcgccttt cagtaagttg tcttcggtcg
    13321 ccacaataat cagatgctcg ccctgaacgg caaaaccgat atcgcagaat ggcagtccaa
    13381 cgacattttt cagcgccgga acgcctttgt catacagccg caccagtggt ttatgggcat
    13441 acgcctgctg taacgcttgc gccacttgca cctggctcac acccggtttc aggcggcagg
    13501 taatggtttc gagaatgccg cgcgggaaat tgcccagatg cggggtgaag ataacgtcag
    13561 caccgaggtg tgtggtgatc tctggttgat ggcgatgggt aaagacgcca tacggttgca
    13621 ggctaacttc acaaaaacta tttgaaatcg ctgccttacg tcctgcaccg ctcacgccgc
    13681 tggtggcgtt gatcaccggc cactgattga ggtcaagaag atcggcatca atcaacggtt
    13741 tcagcgccag ctgtgctgcc gtcggataac agcctggcac ggcaatcaag ttcgcttctt
    13801 ttaatttatt accgcaccac tccgccagac cgtaggctgc ctgttccagc agttccgggt
    13861 attgatgggt aaagccgtaa tatttttcat agaaggcgac atcgttaaca cgaaacgcgc
    13921 cggaaaggtc gaacaccaca cagcctgctt caagaaattg cggcgctaaa tcgtggctga
    13981 cttcatgggc ggtggcgaga aacaccacgt ccacccctgg gctaaactcg ccgatatccg
    14041 acatcggctg caacggcaga tcaacgatgc cttttagctg cggatgcaaa tcggagatta
    14101 actttcccgc atcattgctt tgcgctgaaa cagtcaaagc ggttatgttc atatgcggat
    14161 ggcgatttac ataggtcact agctctgcgc cagcgtagcc actggcaccc acaatcagcg
    14221 tattcaacat cggggctatt caccttctta tgtctggttg ccaggttaaa cgtaaaacat
    14281 tcaccttacg gctggtgggt tttattacgc tcaacgttag tgtattttta ttcataaata
    14341 ctgcatgaat attgatacta tcatgaccag aggtgtgtca acaatgaaaa acaaattacc
    14401 gccatttatc gagatttacc gtgctctgat tgccacacct tcaataagcg ccacggaaga
    14461 ggcactcgat caaagcaatg cagatttaat cactctgctg gcggactggt ttaaggattt
    14521 aggcttcaat gtggaagtgc agtctgtgcc aggaactcgc aacaaattta atatgctggc
    14581 cagttgcgga cagggggctg gcggtttgtt gctggcgggg cataccgata cggtgccatt
    14641 tgatgacgga cgctggacgc gcgatccatt tacgttgacg gagcatgacg gcaagcttta
    14701 cggcttaggc accgccgaca tgaaaggctt ttttgcgttt atccttgatg cgctacgcga
    14761 tgtcgacgtc acgaagcttg caaaaccgct ctacattctg gcgactgccg atgaagaaac
    14821 cagtatggcc ggagcgcgtt attttgccga aactaccgcc ctgcgcccgg attgcgccat
    14881 cattggcgag ccaacgtcgc tgcaaccggt acgcgcacat aaaggccaca tctcaaatgc
    14941 cattcgaatt atgggtcagt cgggccactc cagcgatccg tcgcgcgggg ttaacgctat
    15001 cgaactgatg cacgacgcca tcggccatat tttgcaattg cgcgataacc tgaaagaacg
    15061 ctatcactat gaagcgttta ccgtgccata ccccacactc aacctcgggc atattcacgg
    15121 cggcgacgcc tctaaccgta tttgcgcttg ttgtgagttg catatggata ttcgtccgct
    15181 gccaggcatg acactcaatg aacttaatgg tttgctcaac gatgcattgg ctccagtgag
    15241 cgaacgctgg ccgggtcgtc tgacggtcga cgagctgcac ccgccgatcc ctggctatga
    15301 atgcccaccg aatcataaac tggttgaagt ggttgagaaa ttgctcggag caaagaccga
    15361 agtggtgaat tactgtaccg aagcgccgtt tattcaaacg ttatgcccga cgctggttct
    15421 ggggcctggc tcaattaatc aggctcatca gcctgatgaa tatctggaga cgaggtttat
    15481 caagcccacc cgcgaactga tcacccaggt gattcaccat ttttgctggc attaaaacgt
    15541 aggccaaaca atgtcggatg cgatgcttgc gcatcttatc cgacctacac ctttggtgtt
    15601 actcgaggcg attttttaac attcccataa gttacgctta tttaaagcgt cgtgaattta
    15661 atggcgtaaa ttcctgctat ttattcgttt gctgaagcga tttcgcagca tttgacgtca
    15721 ccgcttttac gtggctttat aaaagacgac gaaaagcaaa gcccgagcat attcgcgcca
    15781 atgcgacgtg aaggatacag ggctatcaaa cgataagatg gggtgtctgg ggtaatatga
    15841 acgaacaata ttccgcattg cgtagtaatg tcagtatgct cggcaaagtg ctgggagaaa
    15901 ccatcaagga tgcgttggga gaacacattc ttgaacgcgt agaaactatc cgtaagttgt
    15961 ccaaatcttc acgcgctggc aatgatgcta accgccagga gttgctcacc accttacaaa
    16021 atttgtcgaa cgacgagctg ctgcccgttg cgcgtgcgtt tagtcagttt ctgaacctgg
    16081 ccaacaccgc tgagcaatac cacagcattt cgccgaaagg cgaagctgcc agcaacccgg
    16141 aagtgatcgc ccgcaccctg cgtaaactga aaaaccagcc ggaactgagc gaagacacca
    16201 tcaaaaaagc agtggaatcg ctgtcgctgg aactggtcct cacggctcac ccaaccgaaa
    16261 ttacccgtcg tacactgatc cacaaaatgg tggaagtgaa cgcctgttta aaacagctcg
    16321 ataacaaaga tatcgccgac tacgaacaca accagctgat gcgccgcctg cgccagttga
    16381 tcgcccagtc atggcatacc gatgaaatcc gtaaactgcg cccaagcccg gtagatgaag
    16441 ccaaatgggg ctttgccgta gtagaaaaca gcctgtggca aggcgtaccg aattacctgc
    16501 gcgaactgaa cgaacaactg gaagagaacc tcggctacaa actgcccgtc gaatttgttc
    16561 cggtacgttt tacctcgtgg atgggcggtg accgcgacgg caatccgaac gtcactgccg
    16621 atatcacccg ccacgtcctg ctactcagcc gctggaaagc caccgatttg ttcctgaaag
    16681 atattcaggt tctggtttct gaactgtcga tggttgaagc cacccctgaa ctgctggcac
    16741 tggttggcga agagggtgcc gcagaaccgt atcgctatct gatgaaaaac ctgcgttctc
    16801 gcctgatggc gacacaggca tggctggaag cgcgcctgaa aggcgaagaa ctgccaaaac
    16861 cagaaggtct gctgacacaa aacgaagaac tgtgggaacc gctctacgct tgctaccagt
    16921 cacttcaggc gtgtggcatg ggtattatcg ccaatggcga tctgctcgac accctgcgcc
    16981 gcgtgaaatg tttcggcgta ccgctggtgc gtattgatat ccgtcaggag agcacccgcc
    17041 ataccgaagc gctgggcgag ctgacccgct acctcggtat cggcgactac gagagctggt
    17101 cagaagccga caaacaggcg ttcctgatcc gcgaactgaa ctccaaacgt ccgcttctac
    17161 cgcgcaactg gcaaccaagc gccgaaacgc gcgaagtgct cgatacctgc caggtgattg
    17221 ccgaagcgcc gcaaggctcc attgccgcct acgtgatctc gatggcgaaa acgccgtccg
    17281 acgtgctggc tgtccacctg ctgctgaaag aagcgggtat cgggtttgcg atgccggttg
    17341 ctccgctgtt tgaaaccctc gatgacctga acaacgccaa cgatgtcatg acccagctgc
    17401 tgaatatcga ctggtatcgc ggcctgattc agggcaaaca gatggtgatg attggctatt
    17461 ccgactcagc aaaagatgcg ggcgtgatgg cagcttcctg ggcgcaatat caggcacagg
    17521 atgcattaat caaaacctgc gaaaaagcgg gtattgagct gacgttgttc cacggtcgcg
    17581 gcggttccat tggtcgcggc ggcgcacctg cccatgcggc gctgctgtca caaccgccag
    17641 gaagcctgaa aggtggcctg cgcgtgaccg aacagggcga gatgatccgc tttaaatatg
    17701 gtctgccaga aatcaccgtc agcagcctgt cgctgtacac cggggcgatt ctggaagcca
    17761 acctgctgcc accgcctgag ccgaaagaga gctggcgtcg cattatggat gaactgtcag
    17821 tcatctcctg cgatctctac cgtggctacg tacgtgaaaa caaagatttt gtgccttact
    17881 tccgctccgc tacgccggaa caagaattgg gtaaactgcc gttgggttca cgtccggcga
    17941 aacgtcgccc gaccggcggc gtcgagtcgc tgcgcgccat tccgtggatt tttgcctgga
    18001 cgcaaaaccg cctgatgctc cccgcctggc tgggtgcagg tacggcgctg caaaaagtgg
    18061 tcgaagatgg caaacagagc gagctggaag ccatgtgccg cgattggcca ttcttctcga
    18121 cgcgtctcgg catgctggag atggtcttcg ccaaagcaga cctgtggctg gcagaatact
    18181 atgaccaacg cctggtcgac aaagcactgt ggccgttagg taaagagtta cgcaatctgc
    18241 aagaagaaga catcaaagtg gtgctggcga ttgccaacga ttctcacctg atggccgatc
    18301 tgccgtggat tgcagagtct attcagctac ggaatattta caccgacccg ctgaacgtat
    18361 tgcaggccga gttgctgcac cgctcccgcc aggcagaaaa agaaggccat gaaccggatc
    18421 ctcgcgtcga gcaggcgtta atggtcacta ttgccgggat tgcggcaggt atgcgtaata
    18481 ccggctaatc ttcctctcct gcaaaccctc gtgcttttgc gcgagggttt tctgaaatac
    18541 tgctgttcta acaccctcgt tttcaatata tttctgtctg cattttattc aaaatctgga
    18601 tatcccttca gatatcctta aggaattgtc gttacattcg gcgatatttt tttcaagaca
    18661 ggttcttact atgcattcca cagaagtcca ggctaaaccc ctttttagct ggaaagccct
    18721 gggttgggca ctgctctact tttggttttt ctctactctg ctacaggcca ttatttacat
    18781 cagtggttat agtggcacta acggcattcg cgactcgctg ttattcagtt cgctgtggtt
    18841 gatcccggta ttcctctttc cgaagcggat taaaattatt gccgcagtga tcggcgtggt
    18901 gctatgggcg gcctctctgg cggcgctgtg ctattacgtc atctacggtc aggagttctc
    18961 gcagagcgtt ctgtttgtga tgttcgaaac caacaccaac gaagccagcg agtatttaag
    19021 ccagtatttc agcctgaaaa ttgtgcttat cgcgctggcc tatacggcgg tggcagttct
    19081 gctgtggaca cgcctgcgcc cggtctatat tccaaagccg tggcgttatg ttgtctcttt
    19141 tgccctactt tatggcttga ttctgcatcc gatcgccatg aatacgttta tcaaaaacaa
    19201 gccgtttgag aaaacgttgg ataacctggc atcgcgtatg gagcctgccg caccgtggca
    19261 attcctgacc ggctattatc agtatcgtca gcaactaaac tcgctaacaa agctactgaa
    19321 tgaaaataat gcattgccgc cgctggctaa tttcaaagat gaatcgggta acgaaccgcg
    19381 caccttagtg ctggtaattg gcgaatcgac ccagcgtgga cgcatgagcc tgtacggtta
    19441 tccgcgtgaa accacgccgg agctggatgc gctgcataaa accgatccga atctgaccgt
    19501 gtttaataac gtggttacgt ctcgtccgta caccattgaa atcctgcaac aggcgctgac
    19561 ctttgccaat gaaaagaacc cggatctgta tctgacgcag ccgtcgctga tgaacatgat
    19621 gaaacaggcg ggttataaaa ccttctggat caccaaccag cagacaatga ccgcccgcaa
    19681 tacgatgctg acggtatttt cgcgccagac cgacaagcag tactacatga accagcaacg
    19741 tacgcagagt gcgcgtgaat acgacaccaa cgtgctgaag ccgttccagg aagtgctgaa
    19801 ggaccctgcg ccgaagaaac tgatcatcgt tcatctgctg ggtacgcata tcaagtacaa
    19861 gtaccgttat ccggaagatc agggcaaatt tgacggtaat acagagcatg ttccaccggg
    19921 attaaacgca gaagagctgg agtcatataa tgattatgac aatgctaacc tgtacaacga
    19981 tcacgtggtt gccagcctga ttaaagactt taaagcgacc gatccgaacg gtttcctggt
    20041 ttatttctct gaccacggtg aagaggttta cgacacgccg ccgcacaaaa ctcaggggcg
    20101 taatgaagac aatccgacgc gtcatatgta caccattccg ttcctgctgt ggacgtcaga
    20161 aaaatggcaa gcgactcatc cgcgtgattt ctcacaggat gttgatcgta aatacagcct
    20221 ggcggaactg atccacacct ggtcagattt ggcgggctta tcttacgacg gttacgatcc
    20281 aacccgttca gtggtgaatc cgcagttcaa agaaactacc cgctggattg gtaacccgta
    20341 taagaaaaac gcactgatcg attacgacac tctgccgtat ggcgatcagg tgggtaatca
    20401 gtaattatca gccagatgtt atttgccgga tgcgacgctt gacgcgtctt atccggccta
    20461 cagatcgcgg cggtaggccg gataaggcgt ttacgccgca tccggcaata caagtcgact
    20521 gaaactgccg caatgtttac atctcactcc catcaggcca cacttttcag gtggcctttt
    20581 ttcataatgc cagttactgt tttcccgtct acatacctaa gggaataaca tgtatcacga
    20641 cgtcagctat ctgctctccc gcctgatcaa cggcccgctg tccctgcgcc agatttactt
    20701 tgccagcagc aacggcccgg tgcccgatct tgcgtatcag gtcgattttc cacgtctgga
    20761 aattgtgctg gaaggtgagt ttattgatac cggcgctgga gcagcgttag ttcccggcga
    20821 tgtgctgtac gtccctgctg gtggctggaa ttttccacaa tggcaagccc ccgccacgac
    20881 ctttagcgtg ctatttggca aacagcaact cggcttcagc gtcgtgcaat gggatggcaa
    20941 acaatatcaa aatctggcga agcaacacgt cgcccgacgc ggcccacgca ttggttcttt
    21001 tctgctacaa acgctcaatg aaatgcaaat gcagtcgcag gagcagcaaa cggccagact
    21061 tatcgtcgcc agcctgctta gccactgccg cgatttgctc ggcagccaaa tacagaccgc
    21121 ctcacgcagc caggctctat tcgaagctat tcgtgattat atcgacgaac gctatgcctc
    21181 cgcacttacc cgcgaatctg tcgcacaggc gttctatatt tcgccaaatt acctctcgca
    21241 cctgtttcaa aaaacggggg ccattggttt taacgaatac ctgaatcaca cgcgactgga
    21301 gcacgctaag acattattga aaggctatga cctgaaggta aaagaagtgg cgcacgcctg
    21361 cggctttgtc gacagcaact acttctgccg tctgtttcgt aaaaataccg aacgctcgcc
    21421 gtcggaatat cgtcggcagt accacagcca actgacagaa aaaccgacta ctccagaata
    21481 agatgggttt gctgcggcgc agaaagcact ttgcgcactg cgctcatcac cctctgcggc
    21541 tcacgcagga aagcgtagat gctgcattgc acgtagcgac aatgttcaaa tcgctcagca
    21601 ccggcaagct cgatatccgt aattaacagc gcaacatccg cccggcggat atcctcgtcc
    21661 gctaaacgat tctccgttcc caacgcgccc tgagtttcaa tgctgacgcc ccacttctct
    21721 aactggcaca acttttccag ccgttccgcc gccatataag tatgcgccac gccgcttacg
    21781 caggcggtta ctgccaccag atatgccatt ttaacctccc acggtaacct gaaatccggc
    21841 ccgttctgcc atttcacgca tcgttgccac atcggctgac gacggcgcag caacctcttt
    21901 catcgaccat gttttcccca gcaggcggta tttcggctcg ccgtactgat gaaacggtaa
    21961 cagatggatc tgcttgatat tcagcgggat cagcacgtcc agcgcctgct gcatattctc
    22021 ccggctgagc gtgaaaccag ggatcagcgg taaacgcggg atcacgttga caccctcact
    22081 caccagcaaa cgcagattct ccagcacgcg ttgcaggttc atcttcacca catcccgcgc
    22141 ctgagccgca tccataattt ttaaatcgaa caacacttca tcgcacaatt tcgccagcgg
    22201 taacagcttg ctggctggcg cgtctccggc agtttcgatg gcgcatgaca caccccatag
    22261 ccgcagtcgc tgtaaaaaac gggtcgcaaa ctccgcctgc attaacactt cgccgccaga
    22321 aagcgtgacg ccgccgccgg acgtgcgaaa gaaaatgtca tctttcatca cttcccgttc
    22381 cagcgcgtca aggctgatat cgcggccaat ccgttcaaat gccccggagg ggcattcatc
    22441 cgcatcacgc aaacatttcg cgcagtgcag acatttcgcc tctctgcgca ccgtctggat
    22501 tttgccggag atcgactccg gattagcaca ccatgggcaa agatgcggac agcctttaaa
    22561 aaagaccacc gtacgaatgc cctcgccgtc attcagtgaa taacgctgaa tgttgaaaat
    22621 gcgcgccaca tcatcgcggc gcgtttccac aacgttacag ctgatgcgct gtccggcgga
    22681 tgatgtcatc ctggatctcc ttcgacagtt cgacaaagaa ggcgctgtat ccggcaacgc
    22741 gcaccaccag cccggcataa tcttgtgggc gctgttgcgc ttcccgtaac gtgtcggcgt
    22801 tcaccacgtt aaactgaata tgctgcaact taagctgggt aaacgcccgt aagaagtcgg
    22861 ccagtttgcg taatcccgct tcaccttcga gggtcgccgg agtgaatttc acgttcagca
    22921 atgtaccgtt agaaagcagt gtgttatcga gcttactgac tgatttcagt accgccgttg
    22981 gtccttgtgc gtcctgaccc agcatgggtg acaagccacc gtctgccagt tgctctccgg
    23041 caaagcgacc gtctggcgtc gcgccaacca ccgctcccaa cgggacatga gcagaaacgg
    23101 tatacgatcc cggcgtgaag tagccgccgc gcgggttctg gtatttttcc acttctttgc
    23161 agtagtggcg taacagttcg gcgctaatgt tatccacctc gtcgatatcg ttaccgtatt
    23221 tctcgaagcg gttaattaag cgagcgcgga ctttttcgcc ttctggcgtg gcgaagttgg
    23281 cttttaatac cgacagcaat tcgtcaaaac ttaaacgctg ttgatcaaaa atcatccctt
    23341 tcaacgcatg gagagaatcg ctcaggttgg cgataccgat cccctgtacg ccggagaagt
    23401 tataacgcgc gccgccatcg gtaatatcgc gacctttttc cagacaatcg ctgataaaag
    23461 acgagagtag cggtacaggt gcccagtcgc gatggccgat atcacaaata ttgctgccct
    23521 caaccatcag ggtgatgtag tggctgatct tggcgcggat ctgttccagt aaaccttcat
    23581 aagtcagcgc agcgttgcct tcattttcat gcaggcagat ttccatcact ttcagcaggt
    23641 taaacatcgc gatgtcatgc aagccgtagg ttctgccggg aatagataat tccacacagc
    23701 ccactacgga atagtcgcgc gcatcttcca gcaaaacgcc acggttgagg aacgctggca
    23761 ctaccacttc atcgttaaag atttgcggaa taccggtgcc gaggcgaatg gtttctgcgg
    23821 ttttcatcag gaacggcgtg tcgatcaagg cgttagtgcg cacgccgagg ttcggttgcg
    23881 gtaattgcac gctttgataa gcgtcaaggc aaaggaacga aagcacgttc accgcgctac
    23941 gtccgttctc ggttaacccg ccgagcagtg cggtatagcc ggtagggaaa ccggcgaaat
    24001 aacgcgcgct actggtggag cgcaacagca cgatgtcgtt gcatttcacc cataaagatt
    24061 cgagcagttc tttcaggaat gccggatctt cgccctgggt taatgatgtc tgatagaacg
    24121 gcaacatata ctggtcgaag cgccccaacg atagcgaact ggcgttggat tcgtattgca
    24181 gaatgatgtt catgtaccag aataactggc acgcctgcca gaacgtctgc ggcttatgtt
    24241 cggcgttatg gcgggagatc tccgcaatag tcagcaattc ttcgcgacgc gggccatcag
    24301 tgcagcttgc cgccatcgtt tccgccagtt cggcgtaacg caaaatatgt ttctgcgagg
    24361 cttccagcag taacagcgct gcctgataaa agtgattctc cggctgttgc tgacaatgtt
    24421 gctgcatctg tgccaccagc tcccccagcc cgtgattcag caggcgcggg taatcaataa
    24481 taatgtgccc ctggccttta tccgtctggt tgatgctgaa aatctgcgtg ctggtcgcgg
    24541 cttttacttc atccgtcatc tgcccgttga tgaaatcttt catcgaacgt ttttcccagt
    24601 acgggaacaa ctcttcgcgg tagatacgtt tatcttcttc gctgatagca aagcggtcct
    24661 gcggacgcgt cgggaattga tccagttctt tcagcagcca gtaagggtcc atttccggcg
    24721 acataatccc ggcgcgtggt tttacggtgc ggttaccggc aatcagttct tcatcacgaa
    24781 tcgaaatttc aacgtgttca aggatatacg ctgttgcttt cgcccgacgc attatcaccg
    24841 gctccccttc ggtttgccga tggctggcgg tataaagcaa cgcccgctcc agcgagattt
    24901 cacgggtatt ggcaaacagt gcagttttga ggcgagagat acgattcgtc atgaggaact
    24961 cctgtgggaa agcgaacccg cccttgcggg cgggataaga acttaagcgg tttgtgccag
    25021 gtgagcttca attttgctca taatggcgtc agcacgcttt accgcgtcgc tgatgttgac
    25081 acgcacgata gtcttgccag caaaacgctc ttcaaatttg atgccgatat ctttggtcaa
    25141 aatcaccata tcggcgcttg ccacgtcttc cgcagtcagt tcattttcca gaccaatcga
    25201 cccctgggtt tctactttta cttcccagcc tttcgctttc gcggcgcttt ccagcgcctc
    25261 tgccgccata taagtatggg caacacctga aggacatgcg gttactgcga taattttcgt
    25321 catggctcgt tcctcaatta attaatttca aaatccagat ccaggtcgtc ttccttctct
    25381 tcagttgaag acccattttt acgcgccaga cttttcagca cgttcacgca gactgccgtc
    25441 acaaccgccc cgacagccac tgccgcgatg taacccaact taccttcaac caccggcagc
    25501 acaatcagac caccccagcc tgcatagcac tgcgcaccga ccagcgccgc agttaccgca
    25561 ccacaaactg aaccgaccat gatggaagga atgacacgca gcggatcggc agcggcgaaa
    25621 ggaatcgccc cttcagtaac gccaacacag cccatcacca gtgccgcctt gccggtttcg
    25681 cgctcttctg cggagaaatt tttacgacca atcagcgtcg ccagccccat ccccagcggt
    25741 ggaacacaaa tcccaacagc ggcaatagcc accacggtat aaacaccctg agcaacgcaa
    25801 atcagcatga aggcataggc cactttgtta accgggccgc ccatatcgaa cgccagcatc
    25861 agacccatga tcaccgccag cataacaatg ctgccctgct gcatcccctg aagccactgg
    25921 gtcaggctgt tggtcaacgc ccccaccggc tcgcccagcc cccacatcat gacgccagcg
    25981 gtaatcagtg tgccgacgat tggaatgatg aagattggca ttaccgagcg cagaacttta
    26041 tgcactggaa ttttcttcag gtaatgcacc acgatgccgc cgataatccc ggcgatcagc
    26101 gcaccaaaga agcccgcgcc aaagctgtta ccaacccagg caccgatagc gcatggagcc
    26161 agcgcagaac gttctgcaat ggaataaccg atgtaagcgg cgaggaaagg caccatcagc
    26221 gtcaaacctg caacgccgat atcaaacagt tttttcagat tcggatcggc tacggcatcc
    26281 ggcactgcgc ctttgccata caacatgacg gaaaccgcca gcaaaatacc gcccgatacc
    26341 acgaagggaa tcatgtgtga aacgcccgtc attaaatgct gacgggtatt tttcaggatc
    26401 tgcaccaact cattcataag ctgctcccgg gcttgcgaaa gcccatgtcc atatttttga
    26461 tggaagaaac aataggcaat cgcaggcgga gcaaacagtg gataaaaagg ccatttactg
    26521 gacttttgta atatcagtac aaaaatgcga tccgcctcat aacttgcgat aatccggaag
    26581 tacgccgcaa aacggcgtct tgtgagacgc gtcgcaaatt gacggttaca ttacatttgt
    26641 ccagcttttg gcagatttgt cacatggcag gccgttgccg tgcgctctta tcctgtaaac
    26701 agaaaaccgt accgggagaa aggcaatggc cctgattgtg gaatttattt gtgagctacc
    26761 taacggcgtc catgcgcgtc cggcaagcca cgttgaaacg ctgtgtaata ctttttcatc
    26821 acaaattgag tggcataacc tgcgcactga ccgcaagggc aacgccaaaa gcgcccttgc
    26881 gctgattggc accgatacgc tggtgggcga taactgccag ttactgattt ccggggccga
    26941 cgaacaggaa gcgcaccagc gtttaagcca atggctgcgc gatgaattcc cccactgcga
    27001 cgcaccgctg gcggaagtaa aatctgacga actggaacca ctgccggttt cactgaccaa
    27061 tctgaatccg caaattatcc gcgctcgcac cgtgtgcagc ggtagcgcag gcggcattct
    27121 gacgccgatc tcttctttag atctcaatgc gctgggtaat cttcccgcag ccaaaggcgt
    27181 tgacgccgaa caatccgcac tggaaaacgg tctgacgctg gtactgaaaa acatagagtt
    27241 tcgtctgctg gatagcgacg gtgctaccag cgcgattctg gaagcgcacc gatccctggc
    27301 tggcgatact tccctgcgcg aacatttact ggcaggtgtc agcgccggat taagctgcgc
    27361 cgaagcgatt gttgccagtg cgaatcactt ttgcgaagag ttcgcccgtt ccagcagcag
    27421 ttacctgcaa gaacgtgccc tggacgtacg cgacgtctgc ttccagttac tccagcaaat
    27481 ctacggtgag caacgcttcc cggcaccggg caaactgacg cagcccgcca tttgtatggc
    27541 tgatgaactg acccccagcc agttcctcga actggataaa aatcatctca aaggtctgtt
    27601 actgaaaagt ggcggcacca catcacatac ggtgatcctt gcccgttcgt tcaacattcc
    27661 gacgctggta ggtgtggata ttgatgccct tactccgtgg cagcatcaga cgatttatat
    27721 cgacggcaac gcaggggcga ttgtggttga gccaggggaa tccgtggccc gttattatca
    27781 gcaagaagcc cgcgtacagg acgctctgcg tgagcaacag cgtgtctggc tgacccagca
    27841 agcgcgtacc gctgacggta tccgcattga aattgccgct aacatcgctc actccgtgga
    27901 agcgcaggcc gcattcggca atggtgcgga aggcgttggt ttgttccgca ctgaaatgct
    27961 ctatatggat cgcaccagtg caccgggtga aagcgagctg tacaacatct tttgtcaggc
    28021 gctggagtct gccaacggac gcagcattat tgtgcgcact atggacattg gtggtgacaa
    28081 acccgttgat tatctgaaca ttcccgcaga agctaacccg ttcctcggtt atcgcgcggt
    28141 gcgtatttat gaagaatacg cgtcgttgtt taccacacaa ctacgatcga tcctgcgcgc
    28201 ctctgctcac ggcagcctga aaatcatgat cccgatgatc tcctcaatgg aagagatctt
    28261 atgggtgaaa gaaaaactgg cggaagccaa acagcaactg cgtaacgaac acattccgtt
    28321 tgatgagaag atccagctcg gcatcatgct ggaagtgccg tcggtgatgt tcatcatcga
    28381 tcaatgctgc gaagagattg atttctttag tattggtagt aatgacctga cgcaatatct
    28441 actggcagtg gatcgcgata acgctaaggt gactcgtcac tacaacagcc tgaatccggc
    28501 cttcttgcgg gcgctcgatt acgccgtgca ggcggtgcat cgccagggca aatggattgg
    28561 tctgtgcggt gaactgggag cgaaaggttc cgtgctgccg ttgctggtcg gtttagggct
    28621 ggatgaactc agcatgagcg caccatcaat tccggcggcg aaagcgcgga tggcgcaact
    28681 tgatagccgt gagtgccgcc agttgctcaa ccaggcaatg gcctgccgta cttcgctgga
    28741 agtggaacac ctgctggcgc aattccgcat gacccaacag gacgcaccgc tggtcaccgc
    28801 cgagtgcatc acactggaaa gcgactggcg cagcaaagaa gaagtgctca aaggcatgac
    28861 cgataacctg ctgctggcgg gccgctgccg ctatccgcgt aaactggaag ccgacttgtg
    28921 ggcgcgcgag gccgttttct ctaccggact gggctttagt ttcgccattc cccacagtaa
    28981 atcggaacac attgagcaat ccaccatcag cgtagcgcgt ctgcaagcgc cagtgcgctg
    29041 gggcgatgat gaagcgcaat tcatcattat gttaaccctg aacaaacacg ccgcgggcga
    29101 tcaacatatg cgcattttct cgcgcctcgc tcgtcgcatc atgcacgaag aattccgtaa
    29161 tgcgctggtt aacgccgcct ctgccgacgc tatcgccagc ctgctgcaac atgaactgga
    29221 actgtaaaag gaaacatcat ggaactgtat ctggacaccg ctaacgtcgc agaagtcgaa
    29281 cgtctggcac gcatattccc gattgccggg gtgacaacta acccgagcat tatcgctgcc
    29341 agcaaggagt ccatctggga agtgctgccg cgcctgcaaa aagcgatcgg tgatgagggc
    29401 attctgtttg ctcagaccat gagccgcgac gcgcagggta tggtgaaaga agcgaaacgc
    29461 ctgcgcgacg ctattccggg cattgtggtg aaaattccgg taacctctga aggtctggca
    29521 gcaattaaaa tgctgaagaa agaaggcatt actacgctgg gaaccgcagt gtacagcgcc
    29581 gcgcaaggat tactggcggc gctggctgga gccaaatacg ttgctccata cgttaaccgc
    29641 gtagatgccc agggcggtga cggcattcgt actgtacagg agttgcaagc gttactggaa
    29701 atgcatgcgc cagaaagcat ggtgctggct gccagcttta aaacaccacg tcaggcgctg
    29761 gattgtttgc tggcaggatg tgaatccatc acactgccct tagatgtagc gcaacaaatg
    29821 cttaacaccc ctgcggtaga gtcagctata gagaagttcg agcacgactg gaatgccgca
    29881 tttggcacta ctcatctcta aaggagtaat tatggaccgc attattcaat caccaggtaa
    29941 atacatccag ggcgcagatg taattaatcg tctgggcgag tacctgaagc cactggcgga
    30001 acgctggtta gtggtgggtg acaaatttgt tttaggtttt gctcaatcca ctgtcgagaa
    30061 aagctttaaa gatgctggac tggtagtaga aattgcgccg tttggcggtg aatgttcgca
    30121 aaatgagatc gaccgtctgc gtggcatcgc ggagactgcg cagtgtggcg caattctcgg
    30181 tattggtggc ggaaaaaccc tcgatactgc caaagcactg gcacatttca tgggtgttcc
    30241 ggtagcgatc gcaccgacta tcgcttctac cgacgcaccg tgcagcgcat tgtctgttat
    30301 ctacaccgat gagggtgagt ttgaccgcta tctgctgttg ccaaataacc cgaatatggt
    30361 cattgtcgac accaaaatcg tcgctggcgc gcccgcgcgt ctgttagcgg cgggtattgg
    30421 cgatgcgctg gcaacctggt ttgaagcgcg tgcctgttcc cgtagcggcg cgaccaccat
    30481 ggcgggtggc aagtgcactc aggcagcgct ggcactggct gaactgtgct acaacaccct
    30541 gctggaagaa ggcgaaaaag cgatgcttgc cgccgaacag catgtagtga ctccggcgct
    30601 ggagcgcgtg attgaagcga acacctattt gagtggcgtt ggttttgaaa gcggcgggct
    30661 ggcggcggca cacgcggtac ataacggcct gaccgctatc ccggacgcgc atcactatta
    30721 tcatggtgaa aaagtggcat tcggtacgct gacgcagctg gttctggaaa acgcgccggt
    30781 ggaggaaatc gaaaccgtag ctgcgcttag ccatgcggta ggtttgccaa taactctcgc
    30841 tcaactggat attaaagaag atgtcccggc aaaaatgcga attgtggcag aagcggcatg
    30901 tgcagaaggt gaaaccatcc acaacatgcc tggcggcgcg acgccagatc aggtttacgc
    30961 cgcactgctg gtagccgacc agtatggtca gcgtttcctg caagagtggg aataatctac
    31021 tccaaactcc cggcttgtcc gggagtttga acgcaaaatt gcctgatgcg ctacgcttat
    31081 caggcctacg caatctctgc aatatagtaa atttacgtac ttttgtagac cggataaggc
    31141 gttcacgccg catccggcac gctgtgccag taatctgaaa cttccacgtt gttcgggtgt
    31201 ttttttatcc gcttctggac attttctcca cagaacaatc gttagcccgg aaggtcgaat
    31261 ctgtgactct tattttcacg gacgaaacag atgaaagctt cactggcgtt attcagtctt
    31321 ctgacggtat ttaccagtta ctccttaaaa tctcccgccg ttccaccaac cgtggtacaa
    31381 atccaggcca acaccaatct tgccatcgca gacggcgcca gacagcaaat cggcagcacg
    31441 ctattttacg atccggcgta tgtgcagctt acctatcctg gcggtgatgt cccgcaagaa
    31501 cgcggcgtat gttccgatgt ggtgatccgt gcattgcgca gccagaaggt cgatttgcag
    31561 aaactggtgc acgaagatat ggcgaagaat tttgctgcgt acccgcaaaa atggcagtta
    31621 aagcgcccgg acagcaacat cgatcaccgt cgggtgccta atctggaaac ctggtttacc
    31681 cgccacgata aaacacgccc caccagcaag aaccccagtg actatcaagc gggcgatatt
    31741 gtctcctggc gattagataa cgggctggca catattgggg tggtgtcaga tggcttcgcc
    31801 cgcgacggta cgccgctggt gatacataac attggcgcag gcgcgcagga agaagatgta
    31861 ctgtttagct ggcggatggt ggggcactat cggtattttg ctaaataaga gatctcccca
    31921 catgaagaaa aaattcagat cctttttaca ctgacggctt cttttttctt acggctcacc
    31981 agcgccagtg ccagtacaat cagcacaata ccgctacctt caactgcccc cggattctca
    32041 ccgagcagcc accaggaaaa gagtacgccg caaacgggaa cggccagtgt gcttaagctg
    32101 gcaatactgg caggcaagtt tttcaataca aacaaccata agctccacgc cagcgctgtc
    32161 gccagaatcg cactgtaggc cagcgcccag aacacggtgg gttgccagtc aatttcacgt
    32221 tgcggcacca gtaaagcgac cacgctcatc accagcgccg catacagcat ctgccaggat
    32281 gttagcgaca ataaatccac gcgcggatgg cgggcataca gacgtttagc aacaatcgcg
    32341 ctcgcccccc aactcacacc ggagaggatt gccagcatgg cacttttcat cgaagagaaa
    32401 tcgagttgcc acggctgcaa caccaaaaat aagccgaaag cggcaatcag tatcgcgaaa
    32461 tattgcccac gtcgcaggcg ttcaccgaga aacaacgcgg cgaaaatcac cacccagaac
    32521 ggcatggtat agctcaggat tgccaccttc cccgctccgc cgctgaccag cgcccactgt
    32581 gccaggccaa ccatcccgca ggtttgtaac agggcaatgg ctaaggtgta tttaaacggc
    32641 gtcgggcgca ttccgcgacc acgtaataaa agaacgatga ataaaacgag agcgccgaaa
    32701 atgcagcgta aggcggtgaa gtcgaaggca ccgatgtagc tggtgacttg cttcatgaaa
    32761 atccagctat aactccagat aagtgtgagc acaaccaggc cactgattgc cagtgggttg
    32821 ctctttcctg cggcagacat gagagatcca gtgtgtagtt ttcctgtgga cactatacgc
    32881 cggtaaagaa acttcagcga ctgcatgaaa ggcagtcgct gaagaaggtc agattacagc
    32941 aggtcgaaac ggtcgaggtt catcactttc acccacgctg ccacgaagtc tttaacaaac
    33001 ttctcgtggg catcgctgct ggcgtagact tccgccaccg cacgcaggac agagttagaa
    33061 ccaaagacca gatccgcacg gctggctgtg tatttcactt cgccagtttc gcggtcacgg
    33121 ccttcgaaca gttctttcga ttcgtcggtc gctttccact cgtaacgcat atccagcaag
    33181 ttcacgaaga agtcattgct caatacacca acgcggtcag tgaagacgcc gtttttgctg
    33241 ccatcgaagt tggcacccag tacgcgcatc ccgcccacca gcgcagtcat ttccggcgcg
    33301 gtcagcgtca gttgctgtgc tttatcaatc aacagtgact cggtggtgga aacgtccaga
    33361 cgagcgcgat agttacggaa accgtcagca attggttcca gcagttcgaa catctcaatg
    33421 tcagtctgat cctgacgcgc atcaacgcga cccggcgcaa acggtacatg aatgctcaaa
    33481 cctgcggcgc ttgcggcttt ctcaacgcca accacacctg ccagcacgat gatatccgcc
    33541 agcgaagctt tgccagactc tttctgaatt ttctccagaa ctggcagagc acgaacggct
    33601 gcggcgttca catcccagtc acgctgcggc attaatgcca gacgcgcacc gttggcacca
    33661 ccacgtttgt cgccaccacg gaaggtagaa gcagacgccc aggccaccga taccagctca
    33721 ctaacagaca gaccagaatc cgcaatcgcg aatttcagat cgataatgtc ctgctcggtc
    33781 gggttgtaga tcggctgcgg cagcggatct tgccagatca gatcttcttt cggtacttcc
    33841 ggcccgatgt aacgagattt cggccccata tccctgtgcg tcagtttgaa ccaggcacga
    33901 gcaaaggctt cgttgaacgc ctgcggatcg ttgaggaaac gacgagagat cttctcgaac
    33961 tcaggatcaa aacgcagcgt caggtcggtc accagcatcg tcggtttacg tttcttcgac
    34021 ggatcaaacg gatccgggat aatttccggt gcgtctaccg cttcaaactg gattgcgcca
    34081 gccgggctgc gggtctgtac ccactcatac ttgaacaggt tctcgaagaa atagttgctc
    34141 cactgggtcg gcgtctgggt ccagaccact tccagaccag aggtaatggc atctgcgcca
    34201 acgccgctgc cgtaagtgct cgcccagcct aaaccttgtt cttcaatcgg tgcagcttct
    34261 ggatcaggac ctacatttga tgtcggaccg gcaccgtggg ttttacccag cgtatgacca
    34321 cccgcaatca gcgccacggt ttcttcgtca ttcatgccca tgttgccgaa ggtcgcgcgg
    34381 atagctgctg ctgccgaaag tggttcgccg ctgtgatccg ggccttccgg gttaacgtaa
    34441 atcaggccca tctcggttgc acccagcggt gctttcgcca gcgcttccgg atgacggtga
    34501 gtcagccagg ctttttcatc accccagtta acatccagat ccggttccca gacgtcttca
    34561 cgaccggcac caaaaccgaa ggtacggaag ccggagtttt ccagcgccac gttacccgcg
    34621 aggataaaca ggtcggccca ggagattttc tgaccatatt tctgtttgat tggccacaac
    34681 aggcgacgcg ctttatcgag gcttacgtta tccggccagg agttcagcgg tgcaaagcgt
    34741 tgctgaccac gacccgcgcc gccgcgaccg tcgattgaac ggtaagtacc cgcgccgtgc
    34801 caggccatac gaataaacag accagcgtag ctgccccagt cggcaggcca ccacggctga
    34861 gattctgtca gcagggcttt cagatctttt ttcaggccgt agtaatctaa tttgctgaat
    34921 tctttgcggt agtcaaagtc ctcacccagc gggttagaac gattagaatg ttggtttaac
    34981 aggtcaacac ggagttgatt tggccaccag tcgcgcgtgg ttgtgccccc acctgcgctc
    35041 tggtcgtgac cgccctgatg gaacgggcat ttgccggtgg ctgtcgtgtt atggatatcg
    35101 tctgacgtgc tcatcaatgt gctcccctct acagtgttac cgttacgata cacagcgtta
    35161 gagagaagtt ataattgaat taatccacgg atgcgatagt tgagatctta catattgttg
    35221 gttaaagaga tgtagatcaa attgatcgta attaagactt tttgattatg tccgatttag
    35281 gacaaatgct ttataaaaaa gggttttaga tttgtatcct tcaagtaatg agggagaaaa
    35341 caaggctgat aaccttattt tcccgccctc atttcgaggc agcattttgt gctctgttta
    35401 aaatttgtga acactgtgtg attttcacaa aaggcacaat acttataaac caggtcgaac
    35461 tcccagtgta tggcaaatcg cataactcat ttcagcgcgg ttaagcgtat agaagtggaa
    35521 atctttcact ccttcacggc ttaaaatctt caccatatcc atggcgatat tcgcgcccac
    35581 cagcttgcgg gtttcagcat cgtcatccag gccgtcgaac atttgtgcca tccacgccgg
    35641 aatacgcacg ttggtcatgt cggcaaattt cttcgcctgt ttaaagttcg aaaccggcaa
    35701 aattcccgga atgatttcca catcaatgcc tgccgagacg cagcgatcgc gaaaacgcag
    35761 gtagctttcg acatcgaaga agaactgagt aatggcgcgg ttggctccgg catccacttt
    35821 tcgtctcagg ttgagtaaat cggcctgggc acttttcgct tctggatgta cttccggata
    35881 cgccgccacg gagatatcga aatctgccac ttcttttaac agcgtcacca ggtcagaagc
    35941 atacatttct ggcttaccac ttcccggcgg caggtcgcca cgcagcgcca cgatatggcg
    36001 aataccgtta ttccagtagt cgcgtgcaat gatccgcagc tcggcaggcg tcgcatcaat
    36061 gcaggtaaga tgcggtgccg cttccaggcc ggtgcgatct ttaatgcctt taataatgct
    36121 gtgcgtacgg tcgcgctcgc cggagtttgc gccataggtc accgatacaa acttcggttt
    36181 caggctgcta aggcgatcga tggagttcca cagggtctgc tccatttcac tggtacgcgg
    36241 cgggaaaaat tcgaacgaaa cgttaatctg cccctggact tctgccagac tctgattcag
    36301 ggcatcccgc tggctggcgt gaaaaaagct cataccttac ctcatcaatc gcttatcgtt
    36361 atatgttgtg ttgtgcacat ctatccgttt agacgtccag atgtaaagat gaaggaaaag
    36421 ccgaagggcg tcaaccgaaa aataaccaat gatggtgagg aaaaatcagg gaagatgaaa
    36481 aaaactcatc ttaattagag gcgataaaag atttctctat agcgcaatcc acctcgcacg
    36541 ttttgactca tattctgaca acacagcgac acctgggcta attcgaaaaa caacgtcctg
    36601 ccaccggatg gtgatgttaa ggcatctgat tcggcctgcg ccctcgcgta ggccgaatac
    36661 aggatctgcg caatcaacgg gtaacaaaca gttgagtcaa ttcagtgcgc acttttattt
    36721 gatatccttc acgcgcatac cgttgagctg ttcatccgta atggtgttgc ccgctttgaa
    36781 gtaatcaacc accgcgtgat aaacgtaata accgcccgtt gtgttacgcg ctttcccttc
    36841 ggtaaaggcg gtaaaaccat ctccaccatc agcaaggaaa ctctgagtag caatgtgata
    36901 aaccgtcgca tcttcaatgg gtttgccatt caaagtcagt gtgattaccc gctgaccaac
    36961 cggcctgttg ctgtcgtact tcatttccag gcctttcgat acctgtaaaa cgccattgct
    37021 taaacttgcg ccgtgttcca tcagactgcg taattgttta cccatgagtt ccatcgtcac
    37081 cagttcgttg gggaacggaa acgtactgat gacgccgccc atcgtgatcg cccctgcggg
    37141 gatctcattg cggataccac cagagtttgt taacgccagt tgggtgtttt tacccgccgc
    37201 taccaataaa gcgtcagccg ccaggttccc gagggaagcc gattcaccat aggcacgttt
    37261 taattcaacc ggcgattgcg ccaccgtttg ttgcaccact tcatcaagct ttttattcca
    37321 gccgtcgatc acctgtttcg tttgcggatc gggcttccac tcgtcagcgt aaatggtttt
    37381 aagctcgaag tttttcaccg taaaattatg cggcttctct ttgtagtcga gaaccagttt
    37441 gcccacatca atcccgccgc tgtcagtgga gaggatgagc gtattgccga ctttaatcgg
    37501 ttccggcgta cccacatgtg catgtccggt gatcaaaata tccagccctt tcacctgact
    37561 tgccgtctga atatctttat ccaacgcgcg acgcacatct gtgcctccca tactggactg
    37621 gcgggctgga acaccttcgt ggatcagggc gacggtcaaa tcaaccttgc ctttgagttc
    37681 atcgatataa cgttgtagcc atttaatttc atcgcgcgct tcaataccca cgcgcgtggc
    37741 agcagatacc gtatcattaa aggcaaatac tccgtgcaaa ccaataacgc ctattttcac
    37801 accgtctttt tcgatgatgg tatagggctt atcccagaat gatttactgc tgttctgata
    37861 aaaaatattg ccctgcacaa tagggaattt tgcctggctc aactgtaata atgtgttgtc
    37921 ccagccgtgg tcaaattcat ggttgcctat tgtgacggca tcaaacggca tagtattcat
    37981 aatatcgata atagccttac ctttggtcag gctgctgata tatggcccgg taaaatagtc
    38041 gcccgcatca aaaaaccatg tcgctttatt ttttgctttt tcttgcttaa ccagcgtagt
    38101 gatatttgcc cagccgccaa tatcccgttt accgtcagcg atccacggca ctttataagg
    38161 ctcgacatgt gcatggaggt cgttggtata aatgatggtg acatctttag cgcaagccca
    38221 gaatggcagt gttaatgcga tacccgcagc aagtatttta attttcataa acagtccctt
    38281 tcagtgagat aaaggattgc tacattacgt tctgaaagac ttatttatgt gagagtaatc
    38341 acatccgcag gggatagttg ccggacaaaa tcaacgacct tgtgaaatcg ttggtgatat
    38401 atgtcgactc tgtttacgat taatgcctgt aagtcgtttg gttgccgtaa tttagggcag
    38461 ccaacatcga cagattatag ctggcccgac tatcgactgg gttatccggc actgcactgt
    38521 cgggcatgtg gcagttaccc gccgttgttt gacgagcaac aatttcgtga ctggttgaca
    38581 gttcacttat ctacttttgc aacagagaaa ggccattttt gcccggtatg ttatggcaca
    38641 gagacgattt gttatggtca caatccacag ggttcgcaac gcattcaatg ccgtaactgc
    38701 aaaaaagtat ggacacccaa acaatatcag aaagaaataa cgactcccga aataatcgaa
    38761 acggttgctt tgctcgtgcc atttcaggga gtcagcagcg ggcagaaact gtatgtttta
    38821 atcagttttg atgctcttcg cggtaatatt cttcatcttt ctactaatta cacgcagcat
    38881 caggctggag aaagtctgca ttatcgatac agaggaaatg cagaaccaga gttacacgac
    38941 aataatattg tacaacgcgt tgatatgcgc gaagcacaat ttctacgccg cagtcagttt
    39001 gatgaaattc agtatggcag cgcagcgctc aagcgcaatg ccaaaggcgc tattctgcgt
    39061 ccggttatca ctgcacacgg gcatttcaga gtactgaata ttttattccc tacagtaaaa
    39121 acacatgtaa tttcacacga gtgtttttta agaggtgcca ttattacggc ctgggctgat
    39181 ctgtttcgcc aacagcaagg tgaaatttgg tttattgaag aggaaatagc tgacgatacc
    39241 gataatatgc cctggcgttt tcagggaaaa acttatcacg gctggtggaa aaatcagtgg
    39301 caactctggg ttcagggaaa aaatcgtaaa atggtatgtg cattaacggg cggaaagagt
    39361 agcaaagcag aaatgctctc tttagcaacc agcagacatt ttatcgactg gctacataaa
    39421 caagcagtat ttactcacag cgccccgctt tccgcagggc gcgttacgca aatactgctt
    39481 tctctggctc aggattacaa caactgcgcc agtcggttaa tatccgactg aatcgccccg
    39541 gcggtgacgt cgcgccctgc acctggcccg cggatcacca gcgggttgtc gcgataccag
    39601 cggctttcga tggcaaagac gttatcgcat ggcagtagtg atgccagcgg atggtcttca
    39661 cgcaccgctt ccacgcccac acgcgctttg ccattggcat cgaaacgcgc cacgtagcgc
    39721 agcaccagcc ccatttcgcg ggccgcttcc agtcgttgca ccatctgctc gttaagttca
    39781 tcgccatttt caaagaaatg gtcgatgctg ccgccttcgc aatgggcagg caccagtgat
    39841 tcaacacgta cctggtccgg ttcaatgttg taacccgctt cacgcgccag aatcaccagc
    39901 ttgcgcatta cgtctttgcc ggaaaggtca tcacgcgggt caggttcggt taagccttgc
    39961 tgccacgcct gatccaccag ttcggtaaac ggcacgctac cgtcgaattg caggaacagc
    40021 caggagagcg tgccggagaa gatcccactg atcgacaaaa tggtatcgcc gctgtcgatc
    40081 agatcgcgca cggtatggtt gatcggcaaa cccgcaccga cggtggcgtt gtacagccag
    40141 tgacgcccgg ttttttcgaa ggcgtcgtgg atctggcgat atttattgct gtcgcttgct
    40201 cctgccagtt tgttggcact gatgacgtgg aaaccgtggc tggcgaaatc aagatactgg
    40261 tcagcgagct gctggctggc ggtaacgtcc agcaccacta aatcatcata cggatgggcg
    40321 cgcatccaca ggaacagcga ctcttcatcc tgctcgaccg cttcatcgtt gaagaaggct
    40381 aacgcgcggc tggcgtccag accgtcatag ctcaacaggc tacggcggct gtccaccacg
    40441 cctgccagca caaattcaaa gccggtacgt gccgaaagcg tactctgctc acgggcgaac
    40501 agttccagcc agcgggaacc gatattgccc ttgccgaaca ataccaggcc gatgcgtttt
    40561 tccgcgcgga agacggactg atgcagcccc tgaatcaggc tttcggtcgg gccggtgcgc
    40621 agtactgcca ccaggctgat gccgtcatcg gactgccagg taaattcgac cggctggcct
    40681 ttcagttgct gccagaagcg gtggcaatgc agcgggttac gggtgacgcc cgccccaacc
    40741 atcgccacca gcgccagccc ctgacgcagg cgcagttcgc caggtaatcc cgcttcgtcg
    40801 aggattttca gcgcactgtc ggccacttct gaggtgtagc aaaattgcag caactggcga
    40861 tcgttatgca cgccaaccgc cagtggacgt acctgagcac gtttcaggat ctggtcgatc
    40921 tctttatgcg ccagtttgaa atcctggctg gcgggcacct gaaactcaat caagcagaca
    40981 tcatcatggc tggtgacaat acgcgcacca gtaccggagg ccagcacgcg ttcaatgcgc
    41041 gtggaacctt gatccggcgt gtagctacag cgcagttgca ggtcgatttc gctgccagaa
    41101 acgggctgta aagtacgggc atgaagaacg ggagccgcca gacgcgccag ttcgctggct
    41161 tcatccagac gcagcaacgg cagcaggcag gcatctttca ctttacgcgg gtcggcgcta
    41221 tataccccgg cgacgtcgct ccagatggtt acgcgagaaa cacccgccag cgcaccgatt
    41281 tgtgtcgcgg aatagtcgga accgttacgc cccagcagca ccgtttcacc ggcgttgtta
    41341 cggctgataa acccggtcac caccagacgt ttgcccggat gttgtaccag tagctgttgc
    41401 agcaacgggt aagaaagccc ttcatcaacc tgcggttgcg cagcgcgttc agcgcgtaaa
    41461 aactcgcggg catcaagcca ggccgatggc agcccttgtt gattaagcac cgcagacatc
    41521 aggcgcgccg accacacttc accgtggccc accacttccg catacaccgc atcgttaata
    41581 ccgctgtcga gcaacgccgc caggcgctca agatcgctga caaaagcgct aatgaggtta
    41641 tcggcttctt cggcgggtag caggccgcta atcagatcgc actgataacg acgtaatgtt
    41701 tgttgaacct gatgcgcaga gagacgatcg gtctggctta gtttcaacca gttaatcaac
    41761 tggttagtgg tgctaccggc ggcggaaacc accatcatat cgtcaggctg agagtactcc
    41821 gccataatgc ccgcgacacg caaataacac ttcacatcag ccagactact gccaccaaat
    41881 ttatgcagtt gacgaccttt cgcccctgcc tgcgcaatca cactcatttt taccccttgt
    41941 ttgcagcccg gaagccattt tccaggtcgg caattaaatc ttcgccatct tcaataccgg
    42001 tggagatacg cagcagcgtc tcggagatcc cggcggcagc acgcgcttct ggtgccatgc
    42061 ctgcatgtgt catggttgcg gcgtgagaga ttaaactttc cactccccct aatgattccg
    42121 ccagcgtaaa caacgacagc ccgcccagga aacgacgcag cgtctgctca tcgccatcca
    42181 gttcaaaact caacattgcg ccaaagcctt tttgctggcg cgcggcaatt tcatgcccct
    42241 gattttccgg cagcgacggg tgatacagtt tcttcaccaa cggctgggtt tgcagatatt
    42301 tcacaatcgc ctgcgcgttg cgctgcgcca gctccatacg cggcaccagc gttcgcaacc
    42361 cgcgcagcag cagatagctg tcaaacgcgc cgcccgtcac gccaatattg tttgcccacc
    42421 aggcaagttc agtgacaacg tccgggtctt tagcaatcac tacgcctgcc accacgtcag
    42481 agtgaccgtt cagatatttc gtgcatgaat gcaacaccag atcggcacct aatgccagtg
    42541 gattttgtaa tgccgggctt aagaaggtgt tatccaccac gctcaccgcc ccgacttccc
    42601 ttgccagatg gcaaattttc gcaatatcca cgacgcgtaa caatggatta cttgggcttt
    42661 ctaccagtac cagtttgggt ttttctgcca gcgctgcccg taatgcctgt tcatcgcttt
    42721 gatcaacaaa caacacgcga tagcaaccgc gtttcgccag gctgtcgaac aggcgatagc
    42781 taccgccgta gcagtcgtgc ggcgcaacca gcagatcgcc aggtttcaaa aagacggtcg
    42841 ttaccaggtg aatcgcggac atgccggtat tagtaagtac ggcaccggca ccgccttcca
    42901 gttctgccag cgcacgctga accacatcgc gcgttgggtt gccgcgacgc gagtaatcat
    42961 gcgcacgtgg ttcattaaat ccggtaaagt tataggtact ggaaagatgg atgggaggga
    43021 caacgcaacc atactgttcg tcgtcattta acccgctacg cactgcgatg gtggcctgtt
    43081 tacgcgtcat gtgatgaagt tccctgggct ttgtcggtga aatgtcaggc accagagtaa
    43141 acattgtgtt aatggacgtc aatacatctg gacatctaaa cttctttgcg tatagattga
    43201 gcaaatccca aatagccgtt aaaattatat gcattatcac gccgacaggt gcattacacg
    43261 atgtcacggt aacgcctgta cggtaaacta tgcgggttta cggtcagtac ccacattaac
    43321 tgtgtggtct ggtctcaatt tattgacgaa gaggattaag tatctcatgg ctgaatggag
    43381 cggcgaatat atcagcccat acgctgagca cggcaagaag agtgaacaag tcaaaaagat
    43441 tacggtttcc attcctctta aggtgttaaa aatcctcacc gatgaacgca cgcgtcgtca
    43501 ggtgaacaac ctgcgtcacg ctaccaacag cgagctgctg tgcgaagcgt ttctgcatgc
    43561 ctttaccggg caacctttgc cggatgatgc cgatctgcgt aaagagcgca gcgacgaaat
    43621 tccggaggcg gcaaaagaga tcatgcgtga gatggggatt aacccggaga cgtgggaata
    43681 ctaaagcgga aaagagcggc gcggagttaa ccagccgctt ttttcataca tggacgttta
    43741 acgatgaaaa tcaggctact gatccccggc ctgctggttt ctgtgcctgc atttgcctgg
    43801 caaccacaaa ccggcgacat catctttcag atctctcgct catcgcaaag taaagcgatc
    43861 caactggcga cccattccga ttacagccac accggtatgc tggtgatacg caacaaaaag
    43921 ccctacgtct ttgaagccgt cggcccggta aaatataccc cgctgaaaca gtggatcgcc
    43981 cacggtgaag atagcaagta catcgtgcgt cgcgttaaag gcgagctaaa tgccgaacaa
    44041 cagcaaaaac tggcgcaaac ggcaaaacgt tatctcggta aaccgtatga ctccagcttc
    44101 tcgtggagcg acgatcgcca gtactgttcg gaagtggtgt ggaaggtcta ccagaatgcg
    44161 ctgggaatgc gtgtgggcga gcagcagaag ctgaaagagt tcgatcttag taacccgcta
    44221 gttcaggcaa agctcaaaga acgctacggc aaaaatattc cgcttgagga aacggtagtt
    44281 tcaccacaag ccgttttcga cgcgccacaa ctcaccacgg tcgccaaaga atggccgctg
    44341 ttttcctggt aatacgacca aaattcaggc acaaaaaaag cgccgtgcgg cgcttttttc
    44401 ggaaatccgg tcttatttgc tgcccgggat gttgaaacgc ttgttgaagc ggtcaacacg
    44461 gccaccggta gcaacatcac gctgtttgcc agtgaagaac gggtggcact tgctgcacac
    44521 gtcgaggttc aggtcatgac caacggtgga gcggattttc attacgttac cgcaagagca
    44581 gctagcagta atttcttcgt atttcgggtg aatatctttt ttcatgggaa aacctcggtt
    44641 taaggccgcg tcgctcttcc agccctaacg ccagacacca cgcgatgtta aaagtatagc
    44701 ttcaatacga tcatttcgta cgaaggcgcg aaatcataca gaaattaacc agcgtatgca
    44761 aactgatccg cactcttcta cggcaatgtg tatactaacc caccgaattt caagtcagga
    44821 tgatgctatg cccgttgccc acgttgcctt gcccgttccg cttcctcgta cctttgacta
    44881 tctgctgcca gaaggcatga cggttaaagc cgggagtcgc gtgcgcgtgc cgtttggcaa
    44941 acaacaggag cgcatcgggg ttgtggtgtc agtgagcgat gtcagtgagc tgccgcttaa
    45001 cgagctgaaa gcggtagttg aagtgctgga cgttgagccg gtatttactc actccgtctg
    45061 gcgattactg ctctgggcgg cagattacta tcatcatccg attggcgatg tgctgtttca
    45121 tgccttgccg attttactgc gccaggggcg gcctgcggca aacgcgccta tgtggtactg
    45181 gtttgccact gaacaaggtc aggcggtgga tctgaacagc ctgaaacgtt cgccaaagca
    45241 acaacaggcg ctggcagcgt tacggcaagg caaaatctgg cgcgatcagg ttgccacgct
    45301 cgaatttaat gatgccgcgt tgcaggcact gcgcaaaaaa ggtctgtgtg atttagcaag
    45361 tgaaacacca gagtttagcg actggcgaac gaactatgcc gtttctggtg agcggttgcg
    45421 gttgaatacc gaacaggcca ccgccgttgg cgcaattcat agcgcggcag atactttttc
    45481 tgcctggctg ctggcgggcg ttaccggttc cggtaaaacg gaggtttatc tcagtgtact
    45541 ggaaaacgtg ctcgctcagg gcaaacaggc gctggtgatg gtgccggaaa tcggcctgac
    45601 accgcaaact atcgcccgtt ttcgtgaacg ttttaatgcc ccggtggaag ttctgcattc
    45661 cggcctgaac gacagcgagc gtctttcggc gtggttgaaa gcgaaaaatg gcgaggcggc
    45721 gattgtcatc ggcacccgct ccgcgctgtt tacgccgttt aaaaatctcg gcgtgattgt
    45781 tattgatgaa gagcacgaca gttcctacaa acagcaggaa ggctggcgct atcatgcccg
    45841 cgacctggcg gtgtatcgcg cgcatagcga gcaaatccca attattcttg gctccgcaac
    45901 gcccgcactg gaaacgttat gcaacgtgca gcagaaaaaa taccgcctgc tgcgcctgac
    45961 ccgtcgggcg ggcaatgcgc gcccggcaat tcaacatgtg ctggatttaa aaggtcagaa
    46021 ggtgcaggca ggtctggctc cggcgttgat cacccgtatg cgccagcatt tacaggccga
    46081 caaccaggtt atcctctttc ttaaccgccg gggttttgcg cctgcgctac tgtgccacga
    46141 ctgtggctgg attgccgaat gcccgcgttg cgatcactac tacacgctgc atcaggcaca
    46201 acagcatttg cgctgtcacc actgtgacag ccaacgcccg gtgccgcgcc agtgcccttc
    46261 ctgcggttcc acacacctgg tacccgtggg gctgggcacc gaacagcttg aacagacgct
    46321 cgcgccgctg ttccccggcg tgcccatttc tcgtatcgac cgcgatacca ccagccgcaa
    46381 aggggcgctg gaacagcaac tggcggaagt gcatcgcggc ggcgcgagga tcttgattgg
    46441 cacgcaaatg ctggcgaaag gtcaccactt tccggatgtg acgctggtag cgttactgga
    46501 tgtggacggc gcgctgtttt ctgccgattt tcgctcggca gagcgtttcg ctcagcttta
    46561 cacccaggtc gctggtcgtg ccgggcgtgc gggtaaacag ggcgaagtgg tgctgcaaac
    46621 gcaccatccg gaacatcctc tgttgcaaac gttgctctat aaaggctacg acgactttgc
    46681 cgaacaggcg ctggctgagc gacggatgat gcagctgccg ccatggacca gccatgtgat
    46741 tgtgcgtgcg gaagatcata acaatcagca cgcgccgctg ttcctgcaac agttgcgtaa
    46801 tctgatcctc gccagcccgc ttgcagacga caaactgtgg gttctcggtc cggttccggc
    46861 actggcccct aagcgtggtg gccgctggcg ctggcaaatt ttgttgcagc acccttcccg
    46921 cgtgcgatta cagcacatca tcaatggtac gctggcgctt attaatacaa taccggattc
    46981 ccgtaaagtg aaatgggtgc tggatgtcga tcccatcgag ggctaaaccg ctcacgatgc
    47041 gaggcggatc gaaaaattca atattcatca cacttttcat gaaaattctg taaccgtttt
    47101 cacgcgctat ctgctaaaaa tgttgccgat gtgaagtaaa catggatgta gtacgcctga
    47161 cgtgccaggc gaggagtgag tgtgaaagcg aagaagcagg aaactgccgc gaccatgaaa
    47221 gacgttgccc tcaaggcaaa agtctctaca gcgactgtct cccgagcatt aatgaatccc
    47281 gataaagtct cccaggccac ccgtaatcgg gttgaaaaag cggcccggga agtgggttat
    47341 ttaccgcagc ctatggggcg caacgtcaag cgtaatgaat cccgcaccat tctggtgatt
    47401 gtcccggata tctgcgaccc tttctttagc gaaattattc gcggtatcga agttacggcg
    47461 gcaaatcacg gatatctggt gctgattggc gactgtgcgc atcaaaatca gcaggaaaaa
    47521 acctttatcg atttgatcat caccaagcaa attgatggca tgttgttgct gggttcaagg
    47581 ctgccgtttg atgccagcat tgaggaacag cgtaatctgc cgccgatggt gatggcgaac
    47641 gaatttgcac cggaactgga gctgcctacc gttcatatcg acaatctgac cgccgcattt
    47701 gatgcagtaa attatttata tgagcaaggg cataaacgga ttggctgtat agccggtccc
    47761 gaagagatgc cgctgtgtca ctaccgcctg caaggctatg ttcaggcgct gcgtcgctgc
    47821 ggcattatgg ttgatccgca atacatcgcc cgtggcgact tcaccttcga agccggaagc
    47881 agagcaatgc aacagctgct tgatcttcca caaccgccta ctgctgtctt ctgccatagc
    47941 gatgtgatgg cgctcggcgc actttctcag gcaaaacgtc aggggctgaa agtcccggaa
    48001 gacctttcca taatcggttt tgataacatc gacctgacgc aattttgtga tccgccgctg
    48061 acaaccatcg cgcagccgcg ttacgaaatc ggtcgggaag ctatgctgtt attgcttgat
    48121 caaatgcagg ggcaacacgt tggcagtggc tctcgtttaa tggactgcga acttatcatc
    48181 cggggatcaa cacgcgcgtt accttaaagt aaacctttaa gactgccgtg actggtcaaa
    48241 ggcccgccgc ttaagtaaca tggcgggctg acgaacgaat aaatacagcg aaacgatagt
    48301 ggcacaacga gattatgtac gccgcagcca accggcacct tcgcggcgaa aaaagagcac
    48361 ctcacggaaa aagcaacgaa atctgcctgc ggtttctccc gctatggtcg ctattgctgc
    48421 cgccgttctt gtgaccttta tcggtggtct gtacttcatt acgcatcaca agaaagaaga
    48481 gtccgagacg ctgcaaagcc agaaagtgac cggaaacgga ctaccaccaa aaccagaaga
    48541 acgctggcgc tacattaaag agctggaaag tcgccagccg ggtgtgcgtg cgcccacaga
    48601 accttctgcc ggtggtgaag tgaaaacgcc ggagcaactg acaccagaac aacgccagct
    48661 tcttgaacaa atgcaggccg atatgcgcca gcagccaacg cagctggttg aagttccgtg
    48721 gaatgagcag acgccggaac agcgtcagca aacgctacag cgccagcgtc aggcgcagca
    48781 attagcggag cagcaacgcc tggctcagca gtcgcgtacg actgaacaaa gctggcagca
    48841 gcagacgcgt acgtcgcaag ccgcgccggt acaggcgcaa ccgcgccagt ctaaaccggc
    48901 ttctactcag cagccgtacc aggatctgct gcaaacccct gcgcacacga ccgcgcagtc
    48961 gaagccgcag caagctgcgc cggttgctcg tgccgctgac gcgccaaaac cgacggcgga
    49021 gaaaaaagac gaacgccgct ggatggtgca gtgcggttcg ttcagaggcg cggaacaggc
    49081 agagacggta cgtgctcagc tggcgttcga aggctttgac tcaaaaatta ccaccaacaa
    49141 tggctggaat cgtgtggtga ttggcccggt gaaaggcaaa gagaacgcag acagcaccct
    49201 caatcgcttg aagatggcgg gtcatacaaa ctgcattcgg ctcgccgccg ggggttgaaa
    49261 ccctcaaaat cccccccatc tataattgca ttatgccccg tacttttgta cggggtttgt
    49321 actctgtatt cgtaaccaag gggtcagctc gtgacaacta tagtaagcgt acgccgtaac
    49381 ggccatgtgg tcatcgctgg tgatggtcag gccacgttgg gcaataccgt aatgaaaggc
    49441 aacgtgaaaa aggtccgccg tctgtacaac gacaaagtca tcgcgggctt tgcgggcggt
    49501 actgcggatg cttttacgct gttcgaactg tttgaacgta aactggaaat gcatcagggc
    49561 catctggtca aagccgccgt tgagctggcg aaagactggc gtaccgatcg catgctgcgc
    49621 aaacttgaag cactgctggc agtcgcggat gaaactgcat cgcttatcat caccggtaac
    49681 ggtgacgtgg tgcagccaga aaacgatctt attgctatcg gctccggcgg cccttacgcc
    49741 caggctgcgg cgcgcgcgct gttagaaaac actgaactta gcgcccgtga aattgctgaa
    49801 aaggcgttgg atattgcagg cgacatttgc atctatacca accatttcca caccatcgaa
    49861 gaattaagct acaaagcgta aggatctccc atgtctgaaa tgaccccacg cgaaatcgtc
    49921 agcgaactgg ataagcacat catcggccag gacaacgcca agcgttccgt ggcgattgct
    49981 ctgcgtaacc gctggcgtcg catgcagctc aacgaagagc tgcgccatga agtgaccccg
    50041 aaaaatatcc tgatgatcgg cccgaccggt gtcggtaaaa ctgaaatcgc ccgtcgtctg
    50101 gctaagctgg cgaatgcgcc gttcatcaaa gttgaagcga ccaaattcac cgaagtgggc
    50161 tatgtcggta aggaagtgga ttctattatt cgcgatctga ccgatgccgc cgtgaaaatg
    50221 gtacgcgtcc aggctatcga gaaaaaccgt tatcgcgctg aagaactggc agaagaacgt
    50281 attctcgacg tactgatccc accggctaaa aataactggg gacagaccga acagcagcag
    50341 gagccgtccg ctgctcgtca ggcattccgc aaaaaactgc gtgaaggcca gcttgatgac
    50401 aaagaaattg agatcgatct tgccgcagca ccgatgggcg ttgaaattat ggctcctccg
    50461 ggcatggaag agatgaccag ccagctgcag tccatgttcc agaacctggg cggtcagaag
    50521 caaaaggcgc gtaagctgaa aatcaaagac gccatgaagc tgctgattga agaagaagcg
    50581 gcgaaactgg tgaacccgga agagctgaag caagatgcta tcgacgctgt tgagcagcac
    50641 gggatcgtgt ttatcgacga aatcgacaaa atctgtaagc gcggcgagtc ttccggtccg
    50701 gatgtttctc gtgaaggcgt tcagcgtgac ctgctgccgc tggtagaagg ttgcactgtt
    50761 tccaccaaac acgggatggt caaaactgac cacattctgt ttatcgcttc tggcgcgttc
    50821 cagattgcga aaccgtctga cctgatcccg gaactgcaag gtcgtctgcc aatccgcgtt
    50881 gagctgcagg cactgaccac cagcgacttt gagcgtattt tgaccgagcc gaatgcctct
    50941 atcaccgtgc agtacaaagc actgatggca actgagggcg taaatatcga gtttaccgac
    51001 tccggtatta agcgcatcgc ggaagcggca tggcaggtga acgaatctac cgaaaacatc
    51061 ggtgctcgtc gtttacatac cgttctggag cgtttaatgg aagagatttc ctacgacgcc
    51121 agcgatttaa gcggtcaaac tatcactatt gacgcagatt atgtgagcaa acatctggat
    51181 gcgttggtgg cagatgaaga tctgagccgt tttatcctat aatcgcgttc aatcattttc
    51241 atcattgttt gatggggctg aaaggcccca tttttattgg cgcgtattat gactgaacaa
    51301 caaattagcc gaactcaggc gtggctggaa agtttacgac ctaaaaccct ccccctcgcc
    51361 tttgctgcaa ttatcgtcgg gacggcgctg gcatggtggc aaggtcactt cgatccactg
    51421 gtcgccctgc tggcattgat taccgccggg ctattacaga tcctttctaa cctcgccaat
    51481 gattacggcg atgcggtaaa aggcagcgat aaacctgacc gcattgggcc gctacgcggc
    51541 atgcaaaaag gggtcattac ccagcaagag atgaaacggg cgctcattat taccgtcgtg
    51601 ctcatctgtc tctccgggct ggcactggtt gcagtggcgt gccatacgct ggccgatttt
    51661 gtcggtttcc tgattcttgg cgggttgtcg atcattgccg ctatcaccta caccgtgggc
    51721 aatcgtcctt atggttatat cggtttgggt gatatttccg tactggtttt ctttggctgg
    51781 ttgagcgtca tggggagctg gtatttacag gctcatacat tgattccggc actgatcctt
    51841 ccggcaaccg catgcggcct gctggcaacg gcagtactga acattaataa cctgcgtgat
    51901 atcaatagcg accgcgaaaa cggcaaaaac acgctggtgg tgcgcttagg tgcagtaaac
    51961 gcgcgtcgtt atcatgcctg cctgctgatg ggctcactgg tgtgtctagc gctgtttaat
    52021 ctcttttcgc tgcatagcct gtggggctgg ctgttcctgc tggcggcacc gttgctggtg
    52081 aagcaagctc gttatgtgat gcgcgaaatg gacccggtgg cgatgcgacc aatgctggaa
    52141 cgcactgtca aaggagcgtt actgactaac ctgctgtttg ttttagggat attcctaagc
    52201 cagtgggcag cataactgac aaatatcaat taacaattga tgattttgcc aacagcccac
    52261 atagcgcgat atactgaaaa ttctcgcagc aactgaatgt taagcctatg aaatacgata
    52321 cttccgagct ttgtgacatc tatcaagaag atgttaacgt cgtggaaccg ctgttctcca
    52381 actttggcgg acgggcgtcg tttggcggac aaataatcac ggtaaaatgt ttcgaggaca
    52441 acgggttgct gtacgatctg ctcgaacaga atggccgtgg tcgtgttctt gtcgtcgatg
    52501 gcggaggttc tgttcgccgc gcactggtcg atgctgaact ggcgcgtctg gcagtacaaa
    52561 atgaatggga aggcctggtc atttacggcg cggtgcgtca ggtagatgac ctggaagagt
    52621 tggatatcgg catccaggcg atggcggcaa ttccggttgg tgccgctggc gaaggcattg
    52681 gcgaaagcga tgtccgcgtc aattttggcg gtgtcacctt cttctccggc gaccatcttt
    52741 atgccgacaa taccgggatt attctttcag aagatccgct ggatattgaa tgataaaaaa
    52801 ggcaccgcaa ggtgcctttt ttctgcgtta cctgttggcc tacacagtaa agaaattacg
    52861 cgaaagatga agtgtaatca gacctcttcc atgcgaccca gcagggcctg cagacgttcc
    52921 tgccagccgt tctgctgttc tttcagatgg ttgttctcac gctccagctc ttcgcgctga
    52981 tgctgggcat tttgaacttc ctgcgacagt gagttgtttt tttctttcag ctcttcgatt
    53041 tccatctgca acagagtgat ggtatcaatc gcctgctgta cttttgcttc cagtttctca
    53101 aacacttcta atgacattgt catacctctc ctgaattgca aggcgttgat ggataaaaat
    53161 cctcgtcccg attaccggtg acgccttaat aaatacgagc gcactttagt tagctccgat
    53221 tgtatgaagc cgcgccatcg ctgtccagcg gcacgccttg cagattacgg tttgccacac
    53281 ttttcatcct tctcctggtg acataatcca catcaatcga aaatgttaat aaatttgttg
    53341 cgcgaatgat ctaacaaaca tgcatcatgt acaatcagat ggaataaatg gcgcgataac
    53401 gctcatttta tgacggagca cacacatttt aagttcgata tttctcgttt ttgctcgtta
    53461 acgataagtt tacagcatgc ctacaagcat cgtggaggtc cgtgactttc acgcatacaa
    53521 caaacattaa ctcttcagga tccgattatg agtcaaacat caaccttgaa aggccagtgc
    53581 attgctgaat tcctcggtac cgggttgttg atttttttcg gtgtgggttg cgttgcagca
    53641 ctaaaagtcg ctggtgcgtc ttttggtcag tgggaaatca gtgtcatttg gggactgggg
    53701 gtggcaatgg ccatctacct gaccgcaggg gtttccggtg cgcatcttaa tcccgctgtt
    53761 accattgcat tgtggctgtt tgcctgtttc gacaagcgca aagttattcc ttttatcgtt
    53821 tcacaagttg ccggcgcttt ctgtgctgcg gctttagttt acgggcttta ctacaattta
    53881 tttttcgact tcgagcagac tcatcacatt gttcgcggca gcgttgaaag tgttgatctg
    53941 gctggcactt tctctactta ccctaatcct catatcaatt ttgtgcaggc tttcgcagtt
    54001 gagatggtga ttaccgctat tctgatgggg ctgatcctgg cgttaacgga cgatggcaac
    54061 ggtgtaccac gcggcccttt ggctcccttg ctgattggtc tactgattgc ggtcattggc
    54121 gcatctatgg gcccattgac gggctttgcc atgaacccag cgcgtgactt cggtccgaaa
    54181 gtctttgcct ggctggcggg ctggggcaat gtcgccttta ccggcggcag agacattcct
    54241 tacttcctgg tgccgctttt tggccctatc gttggcgcga ttgtaggtgc atttgcctac
    54301 cgcaaactga ttggtcgcca tttgccttgc gatatctgtg ttgtggaaga aaaggagacc
    54361 acaactcctt cagaacaaaa agcttcgctg taatatgact acgggacaat taaacatgac
    54421 tgaaaaaaaa tatatcgttg cgctcgacca gggcaccacc agctcccgcg cggtcgtaat
    54481 ggatcacgat gccaatatca ttagcgtgtc gcagcgcgaa tttgagcaaa tctacccaaa
    54541 accaggctgg gtagaacacg acccaatgga aatctgggcc acccaaagct ccacgctggt
    54601 agaagtgctg gcgaaagctg atatcagttc cgatcaaatt gcagctatcg gtattacgaa
    54661 ccagcgtgaa accactattg tctgggaaaa agaaaccggc aaacctatct ataacgccat
    54721 tgtctggcag tgccgtcgta ccgccgagat ctgcgaacat ctcaaacgcg atggcatgga
    54781 agagtacatt cgtaacaaca ccggtctggt gattgacccg tacttctctg gcaccaaagt
    54841 gaagtggatc ctcgaccatg tggaaggctc tcgcgagcgt gcgcgtcgtg gtgaattgct
    54901 gtttggtacg gttgatacgt ggcttatctg gaaaatgact cagggccgtg tccatgtgac
    54961 cgattacacc aacgcctctc gtaccatgtt gtttaacatc catactctgg actgggacga
    55021 caaaatgctg gaggtgctgg atattccacg cgagatgctg ccagaagtgc gtcgttcttc
    55081 cgaagtatac ggtcagacta acattggcgg caaaggcggc acgcgtattc caatctccgg
    55141 gatcgccggt gaccagcagg cggcgctgtt tggtcagttg tgcgtgaaag aaggaatggc
    55201 gaagaacacc tacggtaccg gctgctttat gctgatgaac actggcgaga aagcggtgaa
    55261 atcagaaaac ggcctgctga ccaccatcgc ctgcggcccg actggcgaag taaactatgc
    55321 gctggaaggt gcggtgttta tggcgggcgc gtccattcag tggctgcgcg atgagatgaa
    55381 gttgattaac gacgcctacg attccgaata ttttgccacc aaagtgcaaa acaccaatgg
    55441 tgtgtatgtg gttccggcct ttaccgggct gggtgcgcca tactgggatc cgtatgcacg
    55501 cggggcgatt ttcggtctga ctcgtggggt gaacgctaac cacattatac gcgcgacgct
    55561 ggagtctatt gcttatcaga cgcgtgacgt gctggaagca atgcaggccg actccggtat
    55621 tcgtctgcac gcgctgcgcg tggacggcgg tgcggtggcg aacaatttcc tgatgcagtt
    55681 ccagtccgat attctcggta cgcgcgttga gcgcccggaa gtgcgcgaag tcaccgcttt
    55741 gggtgcggcc tatcttgctg gtctggcggt tggcttctgg cagaatcttg acgagctgca
    55801 agagaaagcg gtgattgaac gcgagttccg tccaggcatc gaaaccactg agcgtaatta
    55861 ccgttacgca ggctggaaaa aagcggtcaa acgcgcgatg gcatgggaag aacacgacga
    55921 gtaataatga ttgcctgatg cgacgcttgc gcgtcttatc aggcctacga gtcggataca
    55981 catccggcat cacgcagact ctgaaaccgt gcgggggcaa ccccgcacac atcaataatc
    56041 ccgcccttcc cctgtgctac acttcgcgcc attccttact gcttagagtt tgctatgaga
    56101 cgagaacttg ccatcgaatt ttcccgcgtc accgaatcag cggcgctggc tggctacaaa
    56161 tggttaggac gcggcgataa aaacaccgcg gacggcgcgg cggtaaacgc catgcgtatt
    56221 atgctcaacc aggtcaacat tgacggcacc atcgtcattg gtgaaggtga aatcgacgaa
    56281 gcaccgatgc tctacattgg tgaaaaagtc ggtactggtc gcggcgacgc ggtagatatt
    56341 gctgttgatc cgattgaagg cacgcgcatg acggcgatgg gccaggctaa cgcgctggcg
    56401 gtgctggcag taggcgataa aggctgtttc ctcaacgcgc cagatatgta tatggagaag
    56461 ctgatcgtcg gaccgggagc caaaggcacc attgatctga acctgccgct ggcggataac
    56521 ctgcgcaatg ttgcggcggc gctcggcaaa ccgttgagcg aactgacggt aacgattctg
    56581 gcaaaaccgc gccacgatgc cgttatcgct gaaatgcaac aactcggcgt acgcgtattt
    56641 gctattccgg acggcgacgt tgcagcctca attctcacct gtatgccgga cagtgaagtc
    56701 gatgtgctgt acggcattgg cggcgcgccg gaaggcgtgg tttctgcggc ggtgatccgc
    56761 gcattagatg gcgacatgaa tggtcgtctg ctggcacgtc atgacgtcaa aggcgacaac
    56821 gaagagaatc gtcgcattgg cgagcaggag ctggcacgct gcaaagcgat gggcatcgaa
    56881 gccggtaaag tattgcgttt gggcgatatg gcgcgcagcg acaacgtcat cttctctgcc
    56941 accggtatta ccaaaggcga tctgctggaa ggcattagcc gcaaaggcaa tatcgccacc
    57001 accgaaacgc tgctgatccg tggtaaatca cgcaccattc gtcgcattca gtccatccac
    57061 tatctggatc gtaaagaccc ggaaatgcag gtgcacattc tctgagtgat ttgatcgatt
    57121 gagccttcca gtccttcggg actggaattt ttttgttcgg agaacgaaga taaggcaagt
    57181 caatcaaaac aggagaaaaa catggctgat tgggtaacag gcaaagtcac taaagtgcag
    57241 aactggaccg acgccctgtt tagtctcacc gttcacgctc ccgtgcttcc gtttaccgcc
    57301 gggcaattca ccaaacttgg ccttgaaatt gaaggcgaac gcgttcagcg tgcctactct
    57361 tacgttaact cgcccgacaa tcccgatctg gagttttacc tggtcaccgt ccccgatggc
    57421 aaattaagcc cgcgactggc ggcgctaaaa ccgggtgatg aagtgcaagt ggttagtgag
    57481 gcggcaggct tctttgtgct ggatgaagtc cctgactgcg aaacactgtg gatgctggcg
    57541 actggtacgg cgattggccc ttatttatcg attctgcaat tgggcaaaga tttagaacgc
    57601 ttcaaaaaca tggtgctggt tcacgccgca cgatatgccg ccgacttaag ctatctacct
    57661 ctgatgcagg aactggaaaa acgctacgag gggaaactgc gcattcagac ggtggtcagt
    57721 cgggaaacgg ctgcgggttc gctcactggg cggataccgg cgttaattga aagtggtgaa
    57781 ctggaaagcg cggttggcct gccgatgaat aaagaaacca gccatgtgat gctgtgcggc
    57841 aatccacaga tggtgcgcga tacacaacag ttgctgaaag agacccggca gatgacgaaa
    57901 catttacgtc gccgaccggg ccatatgaca gcggagcatt actggtaagc ggttacttgt
    57961 cgataaacgg cacgatcaag agatccgcac tcaacttatt gatcatcccg cgatatgccg
    58021 gcatcaaacg gttgataaat gagtggtgat gaccacagac aaggaggtcg cactgctctt
    58081 tttgcataat ttccagcagt gtttccggca tttctccgcg ttcaatacgc agttttgtct
    58141 tcggccattg aatatttttc gtcagtttat acagcttgtt atccgactta ttcttcaaca
    58201 attgaagaat atcttctgtt gcagggaagt agatacccgg atacaactcg cttaagccat
    58261 catcaatatg aattaacgtc aggtgagcgt cattatgtct ggcgagctcc agggctttat
    58321 tcaccagtaa ggcatcttct tcattcccgg aaattgccac gccaatgtgt ttataagcca
    58381 tgtttaactc cttctaaagc aactccatca agctaacgaa cgcagtgata actcaaaaat
    58441 aatcatctcg gcctggcatg agaaggtgaa ggccgcatca agctcaactt gcccttccag
    58501 atctttaatc ttataggcca cgctggcccc ttcatctgca gaggatgcag cggcggcaag
    58561 ctctttcagt ttggtcataa aggactctgc ttcttcgcgg gtggcaaaaa agcgcgaaaa
    58621 cttactggta cagttgtcgt tatcaatcac cgtaccgata tcaatcgcac atcctttagt
    58681 actgcattta tctacgacat ctttcatagg gcacctctgt atattcgcct ctctgtcgat
    58741 tacgacttaa gaataatgcg ccgttaaagg aagaacaaac aagtaatgat cttatggatt
    58801 accatttttt ttgatattgc ttaaggtgaa gagttcagaa ggattttccg ggcattgtca
    58861 cttgcatcgt ggaaataaca atcccggaaa aaaatagcga taagagatat attaaaggtt
    58921 aattacttga tttattgtcg gctttatact tcacatcctg ggtatcttta ccatatttat
    58981 tttcgccttg tgtgccaaca aacgcaccaa gatcgataag catcatcacc agaatcagtg
    59041 ttgggataaa acgccccacc gcccattgcc atacccccgg caaaattgcc cagttacccg
    59101 ccagcagcat ccacgccaca atcatcagaa atgcccatgc gccggaacgc ccgcgatcat
    59161 gcaagcgctt aacggttact gccgctgttg gccaaagcaa gcacacaagg caaaacgccg
    59221 cggtctgaat atcgagtaaa tttttacccg ccagtgagaa aagcaccagc atgcctgcga
    59281 accacaggcc tatccaaatc cagaaatcac ggcgtccaat acgcccttta aatgagaata
    59341 accattgctg tatggtcatg taagttcctt gatggttgtc ttttccagga ttctaccctt
    59401 ttgacaaggg cgacagatat cgttttaatc ggagccagtc ataacaaaag gtactgtcaa
    59461 tgaagccagg gtgtacgctg tttattctct tatgttctgc attaaccgtt acaacaacgg
    59521 cgcatgcaca aacaccagat acggcaacga ccgcgcctta tctgctggct ggagccccta
    59581 ctttcgatct ctccatcagc cagtttcgag aagactttaa cagccagaat cccagcctgc
    59641 cactgaacga atttcgtgcc atcgacagca gtcccgacaa agccaatctc actcgtgcag
    59701 caagtaaaat taacgagaac ttgtatgctt ctactgcgct ggagcgcggt accttaaaaa
    59761 tcaaaagcat tcaaataacc tggctaccca tccaggggcc agagcaaaaa gccgcgaaag
    59821 cgaaagctca ggcatacatg gcagcggtga tccgcacact caccccatta atgaccaaaa
    59881 ctcaaagcca gaaaaaactg cagtcgctac taacggcggg gaaaaacaaa cgttattaca
    59941 ccgagacaga aggtgcactg cgttatgttg tcgcggacaa cggcgaaaag gggctgacct
    60001 tcgctgttga accgattaag ctggcgctat ctgaatcgct tgaaggtttg aataaatgac
    60061 aaaaagcaaa gcctttgtgc cgatgaatct ctatactgtt tcacagacct gctgccctgc
    60121 ggggcggcca tcttccttta ttcgcttata agcgtggaga attaaaatgc gacatccttt
    60181 agtgatgggt aactggaaac tgaacggcag ccgccacatg gttcacgagc tggtttctaa
    60241 cctgcgtaaa gagctggcag gtgttgctgg ctgtgcggtt gcaatcgcac caccggaaat
    60301 gtacatcgat atggcgaagc gtgaagctga aggcagccac atcatgctgg gtgcgcaaaa
    60361 cgtggacctg aacctgtccg gcgcattcac cggtgaaacc tctgctgcta tgctgaaaga
    60421 catcggcgca cagtacatca tcatcggcca ctctgaacgt cgtacttacc acaaagaatc
    60481 tgacgaactg atcgcgaaaa aattcgcggt gctgaaagag cagggtctaa ctccggttct
    60541 gtgcatcggt gaaaccgaag cggaaaacga agcgggcaaa actgaagaag tttgtgcacg
    60601 tcagatcgac gcggtactga aaacccaggg tgctgcggca ttcgaaggtg cggttatcgc
    60661 ttacgaacct gtatgggcaa tcggtactgg caaatctgca actccggctc aggcacaggc
    60721 tgttcacaaa ttcatccgtg accacattgc taaagttgac gctaacatcg ctgaacaagt
    60781 gatcattcag tacggcggct ctgtaaacgc gtctaacgct gcagaactgt ttgctcagcc
    60841 agacatcgac ggcgcgctgg ttggcggtgc ttctctgaaa gctgacgctt tcgccgtgat
    60901 cgttaaagct gcagaagcgg ctaaacaggc ttaagtctga caggtgccgg atttcatatc
    60961 cggcacttac tttcctaaac tcctcgcctt aacgcaaaat ctcacactga tgatcctgga
    61021 tttcttcggc tgaagcacgg ttcagcgtca gtagatttcg ttgtgtcgcc agcaatacaa
    61081 atgagttatc actctgccgt accatcgcca gcccgtagct tcccatatgt tcccgcgcct
    61141 caggcacttc ttccgccagc atcataaatg ggctgcgttg taccagttcg ctttccgtta
    61201 cccgacgcgc caggtactca tgcccacgca aaccacctgg cagtggcaac cagcggctac
    61261 tgatgttcgc cagattgtta tccagctgtt cgcgcacatc aggacgaata caagaaatat
    61321 gaatatgaaa atggttttgc gtacgcccgg tgcgggagtt gatcgccaga gataccgcgc
    61381 gatcgggaac aggctggccg tatttttggc tcataaaatc acgcgcctgc caggctaacc
    61441 agaaaaaatt aggcgttgac ggatcggtca acaatgggct ttcagtaccg ttaatacggt
    61501 acgttggcat taacagatat tgcagtgggc catgacgatc ttttaaaacc acgtatccgg
    61561 cgttgggttt gacttccgca catggcgacg ggttttggtt ttcctgctgg ttgggcaaac
    61621 attgctcaag aactatctta cgtaacgtgt ctgactcttc accggttaat ttccagtaac
    61681 caataccggc agtcacaacg gcgataacta tcatcaccaa aaaaagaaga cccgcttttt
    61741 tcatcttttt ttccctgtac ctcaaagaga tgcaagggta acgcaaaatc gtgacaaata
    61801 aaaaacccag tggcgagaaa ccaccgggct tgataattat cctggggaaa tcagcgtttg
    61861 ctgatctgat cgaacgtacc gccgttagca aaatgctctt tttgcgcttt cgtccagccg
    61921 ccgaactctt catcaatggt gaataacttc aattttggaa acgcattttc gtactttttc
    61981 gctacctcag cgtcgcgcgg acggtagtag tttttcgctg caatttcctg accttctggc
    62041 gagtagagat atttcaggta ggcttccgcc acctctttgg tgcctttttt ctcgaccact
    62101 ttatcgacca ccgacacggt tggctctgcg aggatagact cactcggcgt gacgatttcg
    62161 aatttatctt tccccagttc attcgctgcc agcagagctt cgttttccca ggcaatcagt
    62221 acatcgccaa ttccgcgctc gacaaaagtg ttagtggatc cacgcgcgcc agaatccaga
    62281 acttcgacgt ttttatacag tgcccgaaca aaatcctgtg cttttgcctg atcgttgttg
    62341 ttgtgatgaa gcgcgtagcc ccaggctgcc aggtaattcc agcgcgcgcc accagagctt
    62401 ttcggattag gcgtgatcac cgaaacaccc ggtttaatca gatcgttcca gtcatggatc
    62461 tgcttcggat tacccttacg taccaggaaa acaatggtgg aagtgtacgg tgcggagtta
    62521 tccggcagac gtttgatcca ctctttatca atccgcccgc gttccgcaat tgcgtccacg
    62581 tcataggcca gagccagcgt gacaacatca gcttcaatac cgttgattac cgacgtcgct
    62641 tgtttgcctg aaccaccgtg tgactgacga atcaccacgt tatcgccagt ttgctgtttc
    62701 cagtgggcgc tgaatgcctt gttgtactgt tcgtacaatt cgcgcgttgg atcatatgaa
    62761 acgttaagaa gctgaatatc ctttgccata acgctggttg ccaccagcaa aaatgttaac
    62821 cctacgcccc actttttcat cgcccgactc tcttatgttg tgttgtgatg agcaaagcgt
    62881 gccagaaggt tgaccaaaca ttaaagaata aaaaaagatt ggctataact tgcgagtata
    62941 tgttggggga ttaaaaaggc ggaagaaatc cgcctcatat tgctgacaaa gtgcgctttg
    63001 tccatgccgg atgcggcaca aacgccttat ccggcctaca aaagtttgca aattcaatag
    63061 attacagaat tcatgtaggc ctgataagcg aagcgcatca ggcctttttg cttctgtcat
    63121 cggtttcagg ctaaaggaat ctgccttttt ccgaaatcat taatacagtt ttttcgcgca
    63181 gtccagccag tcgcctttga acggacgctt catgttttcg atagcgtcga tgatgtcgtg
    63241 gtgaaccagc tgttcgttct ggatacctac gcaacgacca ccgtaacctg ccagcagcag
    63301 atcgatagcg taagcgccca tacgggaagc cagaatacgg tcgtaaggca ccggagaacc
    63361 accgcgctgg atgtggccca gcacagttgc gcgggtttca cgaccggttt ctttctcgat
    63421 gaaatgcgcc agttcgtcaa catcacacat atgttcggta atcgccacga tcgcgtgttt
    63481 tttacctttc gcgatacccg ctttgatttc gtttaccagg tcttcacggc tgaattcaac
    63541 ttccggaacc acaacgaatt cacagccacc ggcaatggcc gcagccaacg tcagatcgcc
    63601 acaataacgg cccatcactt ccaccacgga aatacgctgg tgagaagaag aggtgtcacg
    63661 cagacggtcg atcgcttcta caacggtgct cagcgcagtg aagaaaccga tagtgtagtc
    63721 agtgcctttg atgtcgttgt cgatagtgcc cggcaggccg atgcacggga agcccatttc
    63781 ggtcagacgc attgcaccca tgtaggaacc gtcaccgccg ataaccacca gcgcgtcgat
    63841 cccacgtttt ttcaggtttt cgatagccac ggcgcggatg ttctcgtcgc ggaattccgg
    63901 gaaacgcgca gaaccgagga acgtaccgcc acggttgatc atgtcagaaa cgctgtaacg
    63961 gtctagctgt accatacggt cttcatacag acccagatag ccgtcataaa tgcccattac
    64021 ttccagacct tctgtcagcg cagaacgaac aaccccgcga attgcggcgt tcatgcctgg
    64081 cgcatcaccg ccgcttgtca acacaccgat tttcttaatc atgactacct ctgaactttg
    64141 gaatgcaaaa tgaaatctgt tgccggaagt cttcttgcac atcgaagtga tccaacgaat
    64201 gtgcaaatag tataacaatc acttcctgct gaattgattc aggtcaggcc aaatggcggt
    64261 attttataca caaaatgcgg gtctggctct cttttatact gattatgaaa gcatagaccg
    64321 tttaccctcc ctgggtacga cggaacaggg gtcctgatgg ataatcacat ccgatcccgg
    64381 aaaacgccgt aaaatagcct gctctacctg atccgccacc atatgtgcct gaaccaaagg
    64441 cagagagtct tccatttcca aatgaatctg aataaagcgg gtcggccctg actgccgcgt
    64501 gcgaagatcg tgagcgccgc taacacccgg ccaggaagtc acgatatcaa taatttcttg
    64561 ccgttcctca tcaggcaatg cgcgatccag taatgactgt accgcctcat atcccatgcg
    64621 taacgcgcta tataaaatat agatgccgat ccccaatgca aacagagcat cggcgcgatg
    64681 ccagccgtac caggacaacc ccagcgccag cagaattgcg ccgttcatca taacatcaga
    64741 ctggtaatgt agcatatcag cccgcaccgc ctggctttgc gtccggcgca ccacccaacg
    64801 ctgaaacgag acaaggataa tcgtacaaat tagcgccaca attgtcacga taaccccgac
    64861 gcctggatct gtcatcggtg ttggagatac cagatgttga atacccgtca aaaacaggaa
    64921 tagtgccgaa ccggagataa acatactttg cgccagcgcc gcgagggact cagctttacc
    64981 gtgaccaaac gagtgattat cgtcggcagg ttgcagggaa tatcgcacca ccagtaaatt
    65041 cgtcaacgac gcaccgatat ccaccagcga atccaccagc gcggcgagaa tactcaccga
    65101 cccggtatac caccatgcaa aaattttaat cagcaatagc agcgaagcca tcgccgtcgc
    65161 agcaatcgcc gcccgactga ccagccgtcc ataagattga ttcataaata ctcccgctat
    65221 caactgacgg tagtataacg gaagcaaatc atctgcaatg cattaagcag caggcaaatt
    65281 gaggataaaa aaaaccccca catcatgtgg gggaagacag ggatggtgtc acaaaaaagc
    65341 acctaacctg atgatataaa tggatttata tcaaccactg tccacatagc gtccacatcg
    65401 accataaata aagcccctca actgaggggc tatttttgtg atcacatcca cataatttgc
    65461 tgccctgacg gcaacgggtg cggccttacg gcgtggattt ctcccggctt cacgatgtat
    65521 cgctgtaccg actcataagt gatgaacgtg gcactgcaat tcacgttctg gcactgatga
    65581 taacgctctt ttgtcgtgtc agtgatatag cggcttgtac gcgcatgtgc ggcatgctgg
    65641 cataaaggac aatgaaacat cgcgagcacc tcttccggtt ttgttgatgg tgccatttta
    65701 gttaatttaa ccttataaaa caaacagata aaagaaacac tttactcatc accttctgtt
    65761 tcgtactcca catcagaaag cctgacctca agctctaagg acgtcgtgaa gccgctatta
    65821 ttgagaaaat gtgccacctt agtgattgtc cagtcctgct cgtctatgac gcgcttaaag
    65881 cctgatactt tgaccggcgt ttccgtgtaa atatctgccc gaccagtagc cagactgatg
    65941 gagaactccg caacgccccg ttgcagctta tcccacttcg cctgagcggc gcgcatggcc
    66001 tgcgctttcg tggcatatac cgtggtcagg gcaaaaacgt tgtcagcctc acctgccatg
    66061 tattcacctt cgcgcgcttc cggtactttt ggcgctttct tctgcgtgac tggtttcgct
    66121 ttcgggtgct ccagtgcgcg caggtgtttc tctttctttt tgcgtttcag ttttaccttc
    66181 tgcttttgcg gcttcgggtc tttggtgtgt aaccactttg ccgttacgcc ggtgtaagct
    66241 ccacggtcag caatcgcaaa atgatgacgg tcgccgtcgc tgcgggtgat ggtaatctgc
    66301 gggatttttt taccactggc cgtcaccccc tgccccgctt tgagaaacaa cagttttccc
    66361 atttttacag agacctcacc gccgttgcgt tctgcaagac gggtcaggaa tttcgcatca
    66421 gactcctgcg actggtcgat gtgcgggatt ttaattccgg ccagtgacgg agcgacactg
    66481 gcttccagtc tgttacggga ggctatcgcc tcaacaatcg caccgagcgt ggtgtcatgc
    66541 caggagcctt cacggcggga attgagcgtc ccgcggaaat ctgcactccg ggcgcggatg
    66601 gtgaccacat ccggcgcgcc ccggtgttca acctcatcaa cggtgaattt ccctttgcat
    66661 accagggcaa aacctttcca gccgatatac accgtcagga cagcgccacg aaccggcagc
    66721 ccgacctgcc cgtcggcatc gttcagttca atatcaagct ggtcagcctc aaagccccgg
    66781 ttatcagtca gggtcatgct catcagacgg tcgctgatat tgccggtaat atccctgctg
    66841 tcgagcatca gcatgtaatc cggcgtcagc gtactgcctg catcaaatgt cagcgcgtcc
    66901 agcattatcc cgcccccgtc atacccgtga atttagtcgc catactgcca gccttaccga
    66961 tgagcgattc cgcctgttta ccgatatcgc cataaagcgc ggccagtgat tcatcaacgc
    67021 gggtgagcga caacgtaaaa tcaattttcc ggggtgtgcc gtctgcaaag aaaatactcc
    67081 ctgtttcact caccctgctg atgacataca tgccgtaaat catgccggtg ccatccagca
    67141 acggccacgc ccggccttcc tctgccatca gcctgagcgt ggtcatcgtc agcttcccgc
    67201 cggtcagttc gggataaagc acgccggcaa gcgtcatgtt ttcctcaccc acaccgagaa
    67261 actgaaaggc atcccgttta ccgatacggg aatttgacgg ccagcgataa tctgattcgc
    67321 gctgcatggt ctggtgtggc agcgtctggc gcataaaaac aaacatacct aacgcgagca
    67381 tcatttttcg tcacctcctt aaccgtcatg catcatgctg gcacgggcgc gcgcacgttt
    67441 atcccgctcg tatttttcga gcgcatcctg taactggcgg tcgagctgag tccccggcgc
    67501 agtaccgccc gtcagactga tgtgatattc gtttttactc tggtccacat aagagcgacc
    67561 agccggtgcc gtaaccggct gataagcctg atagcctgca taagagctgg tcgcaggaat
    67621 ataaccaccg gtgccatacg tggcggcatg agttctggtg gctgtctggt caagcgtgcc
    67681 tgactctttg ttgataacac cgagtttttc cagtacccag tcaataccgc tgcgcagttt
    67741 gttgaacgca ttaagcggca gcatcagcgc gtcagccagt gcctgcccga acatgacgcc
    67801 cgtatcacgg caacggttca gggtgtcctg ggtggctttg accggggcaa tcaggttttt
    67861 aaaccactgc cacgcggcct gtaacttttc gcccagccag tcaaacaccg gcttaagtgg
    67921 cgtgaacagt tcccccaccg gcgcaaatgc cgctttcagc ccttccacca caccgccaaa
    67981 gaatgcgctg acaggctccc agtatttacg aataagcaac gccccggcga caatggcggc
    68041 caccacggca acaaccggcc agctaatcgc cccgatggcc gtcataacag cactgccaac
    68101 cgtcgtgaag attgccccca ttgcgcctgc tgccgcgatg atggcattga tgccggtgat
    68161 aaccggccag gctacgaggc caatggcacc gatgacgcca gtcagcgcca gtgcgccacc
    68221 gacaatgagg ccgatggttg acgccagtga tttgtttttc tggatccagc cgtcgagttt
    68281 taacacatac tttgtggccg tctgtgtgag cttacgcagt gcgccttcct gctggtcaaa
    68341 caggtcagtc cccaccgcct cataagcgga ctgaaactcc ttaaagtcac cgccgaggtt
    68401 atcctgcatg attttaacca gctcttccgt tttaccgtcc gaggctttca gcgtggcggt
    68461 cagcgtatcc agttttccgc ttgctgccgc tgccagtaaa acgttcgctg atttcagggc
    68521 ttcctcacca aaaatggttt taaggtattc ccccttctga gacgttccca gcttgtgttt
    68581 atcaaagctg gcctgaatct ctttcagaat ggtgaacaac gggcgcatat ttcccttttt
    68641 gtccgaggtt ttaacgccaa gctctttgag tgcatcccat gctttccctg tcggagcctg
    68701 taatcgggtg acaacggcac tgctacccgt acccgccatt gaccccctga tgttattgtc
    68761 atgcagcaca cctgtcatgg ctgctgcctg ctcaagactt acacctgccg tcttcgcaac
    68821 cgggccgaga taagtcagtg catcactgag tccctgaaaa tcagccgccg acttattcat
    68881 cgttgccgac aacacgtcgc ccacatgact gacatcatca tttgacagtt gaaaggatgc
    68941 cttagtcccc agcaacagtt gcgcgttttc ttccatcgac cgctgattcg ccagtgccat
    69001 attcagcgtg accggcgttg ccgcctgaat agccgcagca tctccaccgg ctttcgcaat
    69061 gataatctgt gcaccggctg catcatccgc cgaggcggca gtattgtcac cgagctggcg
    69121 cgcctgcttg cggagtgcgg ccatttcggc ggagtctttt gccacgccga gcacggcctg
    69181 caattctgag tttttctgcg caaactcata accgggcatc agcaacttaa caccggccat
    69241 cgttcccgcc gccgcaatcc ccacaccggc agcgcccact gaggccatag ttccggccag
    69301 ttcctttccg gcctgataac gctgttttac tgcgttaagt tttgcctgtt gcgcactgac
    69361 acgcgccagc gcgtcacgct gccggttaag ctgcgcggtg gtttcactga tacggttttt
    69421 cagcccctgc tcatcatgtg caagattgcg ggtattaatt cccacagcag ccagttcccg
    69481 ctgctggcgt ttaacggaat ccgtcaggcg gttatatttc gcctgtaagt cctccgctgc
    69541 tcgctttgcg gattccagca ctttcgcctg agcacgggtc ggacgctcgg tgtttttaaa
    69601 ctgtgtggca agggcttcgg cctcctgccg tgccttttca agtgcatgac cagtcacggc
    69661 gagctgtgca ctggtcttgc ggaatccctc aatacgggat gcctgaccgt tcagctcgcg
    69721 cagtgatttt tgtgtttccc ggatatcacc cgacagcgac ctgctcgctg tacggatgga
    69781 tttaaacggg cgggatgcct ggtcaacagc cctgagcaat acctgtaatt ttacattgtc
    69841 actcattcgt gtttccgctt cgccggagcg ccttttcgcg ccatgtgatg agttcggtca
    69901 ggctcatggg atacagttct gatggcggcc agtgaaatat cactgccaca tccgccatca
    69961 ggtcatcgac cgagaaattt ttcgggaacg tcactgcacc gagttcggcg acaaaaaacc
    70021 gaccacctta ccggccagcg ccacaaggtc aggcagttcc agcgcggcga cctcctgctc
    70081 ggtcagcatt ggtgccgtca tgcgcggcag caccttaatc agcgcatcga cttcggagtt
    70141 tgcgaccgca gccagactga caccgcgcag cgtcccggca ttgggtttca tcagcgtgac
    70201 ctgttcgata acctgctcac cacgcttgac cggattgtcc agggtaatca cattttcttt
    70261 gttcatggtt ttctcacttc tgaatcgggg ttaaccggtc agccaggctg accggatgaa
    70321 aatcacaggc cgatattgcg gcggtgttgc tccagccggt cgacgccgtt caccttctca
    70381 atcatgttga tggtgtcgat ttcgaccagc tccttaccgt ccatcgtcag ccggaaatag
    70441 gtgcagacca cggagatttt cgactcggtg tcttctccct gtttgccctc gccggtgtcg
    70501 atttctttct gacgtccacg catgaccact tcgacggcca ccgtttcgcc ggtatcgtca
    70561 cgctggtaag agcctgcaaa acgaatcggc acagcatcca caccggttgc ggcgtaaagc
    70621 tcccagataa ccgaatccgg gaagccaccg agcgaccact ccattgacag cgcatcgtca
    70681 tcaaggccga ggtctaccgg tgcgctgccg ttcatccccg caccgcgata gttttcgagc
    70741 ttacgggtca gttttggcag cgtgacggac tttgcaacgc cctgatagct gtagccgttc
    70801 agaaagacgt tcattaactt gagtttgcgc ggcattgcca tcggtcaggc tccttaattg
    70861 ctgttaaccg aagtgaccag atttgccagg tatttatcgg taatgcgctg gcgcagggtc
    70921 agattttcaa gaggaggcac cggggtatag tcgtagtcga tatacagttt tccggccttg
    70981 agggtttccg catcgttgga ctcttcgctg aaccagcagg tcgcatccac gatatagccg
    71041 tttgttttca gctcacggaa tttggcattg atgccgtcaa cgatgtcgcg aatcagcgtt
    71101 gcggtgatgg gcttgtccac cgcccacatg tgcgcctcag ccatcgtgtc ggccagcacc
    71161 tgcgcggtgc gggtgtagtt ttcaaagagg aacagcggat catcagagca ggtacggtta
    71221 ccccagaagc ggaaaccgtc acggcgaatc agcgttgtga cgcctgactc gttaagcagg
    71281 tcagcatcgg tgccggactc ctgcaaatcc cagaatacgg acgcgctgat gccggtaaca
    71341 ccgttcaccc cgacgttgga cagcgtttta tgccagccct gctcctggtc gattttagcg
    71401 cgcagaccca gcgcacgggc ggtggcatac gcggtggcgg tggtactggc gaccgtatcc
    71461 catgcgagga aatccggcca gatgaccatc agctcacgct ggctgaaatt ctggcggtag
    71521 gctttcacct cggaaatggt tttacagccc catgcgctga tatacccgaa agcgcgcagc
    71581 ttctgacaga ctgatgccag tgcaacagcc acctctttgg tgtccagtcc cggcacgccg
    71641 agaatacgcg gtttaacacc ggttaccgac tctgccgcca gcagggcctt cagtccggtg
    71701 tactgaccgt tttcgtcagt ggtgccgatg atattggaaa cggtctgcgc gagtttcgtt
    71761 tcttcgtctt cgccggtgcc gtcttccaca cgtacgacaa cggtgaccgg ttttgactgg
    71821 tcggcgatag cctgcaacga cgccgccagc gtgccttttt taccggcctt tgcaattgca
    71881 ctctgcacat tggtaatcag caccggttta ttgaggggga agatttccgc atccgcatcg
    71941 ctggccgtgc agaccatgcc aacaatggcg gtggatacgg tggaaatgac gcgggtgccg
    72001 tcgttaatct ccagcacctg cacgccgtga tgatagtcac tcatccgttt aactccgtgg
    72061 ttaatgggtg caactatttt ctgttgggca gtgcatgaga cgctatttga cctggctggt
    72121 cagtggatga aacaacagat aaagaaaagg caggcaattc gcccgcctgt cctgatttgt
    72181 actcactcat tttccgactg acaatttaca tagccaaaac gctatcaaat ctgacagtct
    72241 gctttgagcg aggagcagag gttagtttta gttaaccaaa atgataaaaa gcagtagaaa
    72301 aatccgctca ttacgttatg gttataagcc gcacataatc atccgagcca aatcctcttg
    72361 atttcaaaga attagcactt gctcttcact agaaactatg gttctgactt cacgctcaaa
    72421 tgttggatcc attatcattt ttctatttgt tggaatagta aatttaccga gtaccatgac
    72481 aatgctactc aacggaaata attttggagt aacatttcct aattgaatcg taggatatat
    72541 attaaagccc ccttttatcc tcattggcga accttcaatg aagtgtcgat aattaaattt
    72601 cgccataggg attctcgcca catgcacttt cataattaca gcaacctgag ctatttttac
    72661 tttctggagg taagttgaca atcgttctaa ctgcgttgtt tcatagaaaa aatcagacca
    72721 cgttacagta cttgttccag taacaatttt tatgctgttt ctcttgttgg ggtgagcttt
    72781 tccatattca tagatctccc gtaagctatc catgttcttc acatagggag ctttccgacc
    72841 tctcttgaca taaacgcggt ctgtagtatc agaaggtgga tttgcctgca tagctgcagc
    72901 ttttctgctt aatttagaga tatcatcttc atcgagtata tgtatacgga atatattatt
    72961 acctgtggca agcgcacggc tgatatcatg actggaatca cttgcataaa ttgtattcaa
    73021 tcctgaagtt ccatactgac ataatttgtc atgcgtgaaa tttttttcca gtctaaagaa
    73081 ggcggggata tgcaaggttt tattaaaact ccgacgaata tggcttttga catacaccaa
    73141 atgagcagag caatttgggt caggacattt gagtggatag ggattaacac tataattaaa
    73201 agtatttaca tttactaaaa tctgattgtt atcaatagcc tgagttatac gaataccact
    73261 cattactcct ccataaagat aggcgcaagc atttagtaat aaaccattaa cataccgaga
    73321 tcatacccga tcattgaaat gtaaacactc ccctaagacg gctgctggca taatatttta
    73381 tgacatcagc aatgcccacc tctggcacag agtggactgt cagattaggc tttactctgt
    73441 gccatagata tgtaagccca cactagagct catacaactt attgcggcat ttccggccat
    73501 tcaggatttg caggatccac acgactgacc agaacactat agcgttccca tgcctccagt
    73561 cgactacgct cctcatctgt tgccatattc agcctgaccg cgcgctccag cggcaaaatc
    73621 acggattcag cttcggaaag caaagctgcc ttttgtgatt cggcctgttg ttgttgctcg
    73681 tctgccgtat aaatccgttt aaccacagct ccgtccctaa acatccactt accggaatca
    73741 tcagcgcagc ggttggctgt aatatctgga acctcaacga cgctataacc ttcagggtta
    73801 agcgtggagg catctttggt gatggcgaca ataatattat ttgcatcgta aacaatcttt
    73861 attgtgtctg gctgaaagtt tttcacttcc tcataccagt tttttccgtc ttcggaccat
    73921 aaccagataa catcaaaatt ctttgttagc tgatattgtt cttttgtttt tggatttcca
    73981 gacttaatat tttttaaatg ctgcataaat tacacctgtg cgacgttata ccatgtgcca
    74041 ttgatgtatt tttgtattgg tctgaataca gccggatcat cgccatcaac agagccaata
    74101 atgccaagcc ccgtaattgc atggcctgat ttttcataca tcacgccttt ttgcatagtt
    74161 tgaacaacac gcgtgccaag tctgacatct ctcacatagc gtgagtcaaa attgccataa
    74221 tttccgggaa taatttgcgc accgcaaagc cagttaccgt tattgtccat gtacgcctga
    74281 ccatcggtgc cattggctgt ccttgagtta ttaatcatgt agatgccaaa ttgcttattt
    74341 cccagaccgc caatcataaa tttgcggtcg gcatggtcct gacgaagtaa tgcctgcgca
    74401 ccatcggtgg ataccgcatt gcgtcccaaa ataacattct ggtcacgcat attaatccac
    74461 atgccggtac tactgttaat tgcaaaacgg tttgcaaata tatcccctgt aacatcaaga
    74521 ccatgcccca tgcttatccg accagttcta agattaagcg taaaggggcg tagtggccct
    74581 atatcaccat tttctccctc gttctctcgt gtagggatga tatgcaggca ttcttcagaa
    74641 cggcgaaaaa tggcaccaaa agatgaatta aatatcctca gtgcattgac tgtcgatatt
    74701 tttacttcac tgctgaaaag ggctttaaca agaacagaca aagcatccca tttaagattc
    74761 atcaggtctt ttgttgtggt gctttgtttg cttctccatt tgaaatattc attgccgttg
    74821 tcgcctgttt caaaccacat gtatgaatca gtgtcaccat cggcatcatt tttaaatcca
    74881 atcttcgccc agtcagtatt tcgaatccag gcaaggattg agtcattttc aaaagtaagc
    74941 ccaccggaca aagtatcgcc atttttttgc acggcgttac cagccctgtt taccgtttcc
    75001 tgtaaaccga ggtattcgat aacagcggca acggtcgatt tcgcaagaat atcccgcccg
    75061 acttctgtca gggttgccag actggcaaca tcattccccg taaaatacgg aaacctgtct
    75121 gctgcagtag caagcccggc cagcgccgtc agggtggcat ctttcggttg cttacccgca
    75181 agcgcgttag tcatggtggt cgcaaaattc gggtcgttgc ccagcgccgc cgccagctcg
    75241 ttcagcgtat tcagtgcgtc aggcgacgag tctacaaggg cggcaatcgc ggccatcaca
    75301 taagccgtac ttgcgatctg agtattatta gtaccttttg gcgcagttgg cgtcgttggc
    75361 gttccggtca gtgcagggct gtttaatggc gctttcttgt tcgtttcatc cattaccgtc
    75421 ttaacggctt ttggtgttgc ggcgagcgtt tcagacatgc tgttggtcgc actacttagc
    75481 tggacaagac cttttcgcgc tgtggtagcg tcctgtgcgg tatatttccc gttagcaagg
    75541 tcatatgcgg ccttaaccgc tttcggcgtt gcggccagtg tttcagacgt gctgttggtc
    75601 gcactgctta actgagtaaa accttttgcg gtcagcgagg cgtccgggtg acgtcgtgac
    75661 tgttcgtgct ctgcaatttt gtcatcaacg taatcctgtg tcgccatcac cgttgtggtg
    75721 tcaatggtca gctccactga ggccacactg ctgacgatga tgaccatgcg gcaggtctgc
    75781 gaacgccctg agccttcggc aagggctggc ttataacttt cggccatgtt cgccacggca
    75841 attagcgttc ccgcatcatc gtacaggcca agttcacgca tccagaaacc gcccacctcc
    75901 ggcggaataa ccagctctgc gataatataa ttactgtttc gtttgtcctg gctgattttg
    75961 ttcagcgcat gtcgccagac ttcgtggata agcccggtct gtccggcatc cgggacaggc
    76021 aatttaccac cgccatcccc gacggccatc gtggtaatgt tgaccttccg ccctcccggc
    76081 gcggttgccg ctgccagctt tgctgcaccg gcagtggtga taacggttct gaattttgtg
    76141 ctcattcttc ctcacttatc cggggtaaac cgtaattaca tcgccgtcgt aagccacacc
    76201 accggcgaac aggtagccgg gaatgtcccg ggtaatgttc agaccaataa ggtgacggct
    76261 tgcaggtttg gcatcggcaa tcagccgttc catttcctga tacattgcct ctgtgatacc
    76321 gctttccagt acaccaatat caagccggaa ggtgccgggc gggtcactgt tttcccacca
    76381 ctccgtcacg ttgatgagat agccgagcgg ctccgccaca cgccggattg cacctatcgt
    76441 gcccttatga cagtggatga aatacgcatc gcggataacg gcgcgttttg tcgcttccgg
    76501 ccacttttca tcccacctgt cgaccgaaaa cgcccacgcc agccacggca gcagatttgc
    76561 cgggcaggtg tccgggttcc acagctcacg aatactgacc ggtgtttttt caatttccgc
    76621 acaggctttt gcggcggcaa cttcaagcgg tgatgagccg gtcggcagca gtcgcgaatc
    76681 actcatccga gcctccggtc acgacgcggt attcggtaca gaaagacgcc tgcgtactgt
    76741 tgagcacgat gtcggccagc ggtgcagcca gctcgacacg ctgcacgcct tccacatgca
    76801 aagcggcata aatggcagac agacggatgt cgcgccccag ccggtgctgt gccgtgatat
    76861 acgcttccag ttttttcacg gcggcagcgc gtatgggttc gctttcggga ccagggtaaa
    76921 ggtaaagcgt ggcgtttatc tggtattcaa cgatggcggc agactgcacg gtcacgcggt
    76981 cggccaccgg cctgacgtcc tcgccattaa gggcgttacg caccacggcc agcaggtctt
    77041 cggatgcgac gccgttattt tcacgtgaca gcacagagat ggtgacgcag gccggagaag
    77101 gactggtgac agagatatcc gcgacacgcc cgtcggcact gcgaccatga tactgatagg
    77161 ctcccaccga cccggcgacg cttaaacctt caaacgcctg ctgaatacgc agacgataat
    77221 cggtgtcaga ttccatcact gccggtgtcg gcgggatggt cgaatcatct gccggggtga
    77281 taatcaggcg cgtggtgttg taattggcac caatcacatc aaggtcgtta ccggcggcac
    77341 aggccagcat caccgcccgt gcggcctcat tcacacgctg acgccagata agctcacgat
    77401 aagcattttc ctccagcagt ttgacgagag gctcggattc cagcgtcagg gtacgggcga
    77461 ccgcctcctg ctggtcttcc gggtaaaggg aaatcagtgt cgccttgcgt tcagcgagaa
    77521 tggtttcaaa gtccagctcc tcgaccacat ccggtgcggg tagctggttc aggtcgataa
    77581 tcggcatggt ttcaactcac agggatggtt aacgaaagtg gctggccggt gtcgttgtgc
    77641 tggccggtta gcgtaactgt cattcgcccg tcaaagctgc gcgccgtggt gacggatgac
    77701 agggtgacgc ggggttccca tttcagcacc gccatgtaac aggcgacctt aatctgcaac
    77761 tcaagcgccg gggtctgcgg ctggtcaatc attgacgcca gcaatgagcc gtaatcacga
    77821 cgcatcaccc gtgagccgac cggcgtgcgc aggatatcgc cgatactctg gctgatatgc
    77881 tcaaggtcag tgacagtcag gccatcactg cgattcattc cgagataacg tgctgtcata
    77941 gaggactccc ggttgtgccg ccgctgtcgc cggggtgttt atgggtatgc agtaccttac
    78001 cgtttgatga gagttcaccg ccggtgtgtt caatgttgcc gcgcatcgtc ccgcccttct
    78061 gcacttccag cgtgccggta gtcagcttgt ttgtgcagac cacctccggc gtgtccaggg
    78121 tgacacgggt tgacgctttc accgtgacca ccggtaccgt ggcagtaaca gaatcagaag
    78181 ccgtcacgct ggccgtttta attccgctta ccgtgagtgc actggtttcg ggttcatact
    78241 caatcaccgc cccgtcagag aaacggatat gcagggcatc agccgacgca gacggcgcag
    78301 ggttatcgcc ggaataaatc cccggcagaa cgaacgccgt gtcgagttca ccgcccacgg
    78361 ccagaatcag cacctgttcc cccacggaag gtgcccacca tgtgcgcgaa cgaccggcgc
    78421 gctgggtcag ccactgcagc cagtcggtgc acatgccgcc ggtctgcaca cggcagcgac
    78481 cggcgttaag gtcggtttcg acgacaaggc cggtgcggat catgttgcgc agtgcgcgcg
    78541 cgagttcctg aatatttgcg agagtgttca taacgggaag gatgccgccg ggtcataccg
    78601 gcggcaatgt gacgatgagg tgtcgggaat ggcacaacta acggtcgagg tgagccagga
    78661 taatctcttc aatcatctgc acatcctcac cggtaaagcc gagcagagga cgcgccggat
    78721 aatcaatttt cttaccgtct tttcggtttt cttccgacag accgaactga tgcacactgg
    78781 cgattttcgg tgacttcccg ccgtaaaatt ccattgatgc ctgttccggg ctggcgcgga
    78841 tatgcaaaaa acgactggtg ataagtttcg caaacatttt tcgcttaacg cgaccggtct
    78901 tttttctggc gctctgctgc tggcgtggcg cgtagggtgt gccgtccggg gctttctgtg
    78961 ccatcacccg acgctgctga ctctgacgca gacgtttcgc cagttcggcg ctcagtcgtc
    79021 gacgccctga cggtgacagc gattcaatca gtccggtcaa ccggtcttca aaacgcttaa
    79081 actcattcat cccacttgct caccagttcg ccattgatat aaagctccat cgggcgggtg
    79141 accggctccg gcggcggggg ttccgggata ttcttcacat gcagtgcgcc gtccacctca
    79201 ctgaccagcg tgcgctcggt cagcatcagg ctgatgctga tatcaaagct gctgtcattg
    79261 ttgatgtctg cataaaacgt gaagcccttt ttctggcctt cgtcggtggt catgatgtcg
    79321 ggctgatttt cccgcagcca cgccagcacc ggcacgatga gcaggtcaaa atcaccggta
    79381 aagtcggtca caatgacatt gagcgtgtaa cgcttttcga atgacaacga cgtcgccagt
    79441 gtggaggcaa tactcccgtt atccacgaat atccgcagca tctcgggact ggttttcagc
    79501 accgtgacgg catcagtcag cgccctgcgc aggctgtcgg gtttgagcat cgttttcgtc
    79561 ctgacagtgt ttaatcattt ttacctggct ggcacagcgt gccagcgcgt tctcaagctg
    79621 ccggatatcg gcacttaaat cgccgttcgt ctccgggtca ctgcccggca tcgggcaaag
    79681 gctcactttc gggcaggcgt tgtggacaat cactggcgtc ggtgcaggcc gggcgctggt
    79741 gcaaccggcg cacagcatca ggcaggccag cgccgtacca gcggcgaaaa tcttcgtttt
    79801 cattgagtaa cctcgtgatg gttttctcgc gctgtgcttc acgcttcgcg gcgttttcca
    79861 gttcctgacg cagtgccacc tgcgccagct cgtttttgtc tgccctggtg agtgcaacat
    79921 gaagctggtt tttcagcatg gtgatggtcg tctgctgttc actggcgacg ttgttcaccc
    79981 tgtccagcga ggcgcgcagg ctggcgtttt catgcttcgc cagaaacagc cccgccaccg
    80041 ccagcgataa caacacaacc agcacaatca tcagctttga catggttccc gcccctcaag
    80101 acgttgacgg caggccgtac gtatcagccg gaagaacacc gacgccacga gataaatcag
    80161 cgcggtaaaa atccacccgg cagcgaccag cgagataaat gtcgccacca tcaccaccag
    80221 agccgccgcc cgtctgcacc acggcaccgg ctgcaaaaac agcgacatga caatcttcac
    80281 ggccagcgac tccggtggca gctcccaccc gtagcgttcc agcgcatact cagtggcata
    80341 aacgccgaca ccaccggcaa ccacacagat aaccgtcgcc agaatcgccc aggcagcgac
    80401 aaaattgacg gccacgctct gcgggtaaat cagggacagt gccagcatca gcgccagcga
    80461 cacgtgcagc atcagtgaaa gggataattt cttcatggtg tttactccgt ttaagccggt
    80521 acgccgccag cggtacgcca gacggtgacc agtttttcca gtgaatgctc acgctgaccg
    80581 taaccggcac ccggcaggga cgcccagata ttgcgacagc gtgaaatggc gcgctcaatg
    80641 cgtcccgccc ggatgtcatc cagtgcaccg cgttcgcgga tcaactgaat ggcgagtctg
    80701 tcctgcgaca acggactgaa atccggcagg gcaagctgtt tgcggtagtg cggccagaac
    80761 aggtaaagct gctgatagcg accggaggcc gtggattttt caccgcgacg gttaaacacc
    80821 ttcgccggtc gaccatgtgc gaacgggtgg tcactgtagt cggtgaagat ttccggcttc
    80881 ccgtccagtc cggtgactat cacgtcatag ccccggtttt tcgtcagcgg gtgattcgcc
    80941 gtcccttcgg acacggccag catgtcgaga aaggcagcga tattctgatg cgtgttaatt
    81001 accggcatta ctgtttcccc ctgcccttaa agcggcgctg aatggcaatc tcaatcacct
    81061 gataaccggc gatacccagc atggagccga tgccgcacac cgcaggcagt gacaggtcag
    81121 gaaactgcac cagaacaaca ccggcaacca tcgagacaaa accaccgagc aacatgcgcc
    81181 cgataaacag acgcggggtg atgggttcac caccggcaag caccttgccg acaacaatca
    81241 gcaccccaat catgaaaagc gacaggacgc ttttttcttc tgctgtcatg cgttactccc
    81301 acagattgac agtttcagcc acgggcgcgg tctgaacgtc gggcagttcg acggcggtgc
    81361 cgtgcggcag caccgcaccc agttcagcca gtcccggatt tgcggcgagc acggcctcaa
    81421 ccacgccctc agtgcgcccg taataccgga cacaaatggc gtcgagcgtg tcgccctgta
    81481 gcgcaaaggt cttcatcaga tttgactcac gatgcagcgc ggcttgtcct ggatacgcgc
    81541 caccgcccag cgcatatccc gccacagttc atcaatggtg ctgtcaatgc tgtcagcctt
    81601 cttgtcgcct ttcgcactgg catccacgcc gcgataacgc tcataaagcg acgcggtcgc
    81661 catcgcacac acggcgcgct cgtagtaaaa aactttgata ctttcaccgt cgatgtcgtc
    81721 cgccggaacg tccgccagac gcgtaaaacc ggcggcaatt ttctgttcgc ggtactcgta
    81781 cagctccgca tttgtttcag ccatgcctga cttgatggcc tcacgcagac gggcgggggc
    81841 gacggtctgc tcaaggcgca tacgttcccg gacgcgcttc gggtcgatat cgggaaaaaa
    81901 gaacgtgttt ttaatcaccg gctcgtcgcc tgccggttgc gggatgacca ccgtaccctc
    81961 accggacacg ggagcctcct ttcgcggaat aatcagcgtc atcatgacta cctctgaaaa
    82021 gtcgggcggt ggacgccggt acagcgtcag gtgattcacc ctcactgacc ggcgtgccgc
    82081 cctggcgcgg ggcgcattcg gttgttaact ggctttcttt ttcgggcgtc cacgttttgc
    82141 cggtgtcacg ctccgggtct tacgcggggt acgggtggcc gctttgggct gcggctccgg
    82201 cttcggtttc agctcccgct ccagtcgttc aatctctttt ttgacacctg cctgacagtc
    82261 gagctgtgtc gcacgttgca ggtgagccag cgcaccggcg gcatcaccac catcacgcag
    82321 aaacagacct gtgattttgt gcagctttgc gcgcacttca tcaggcatgt cagccgtggc
    82381 ggtcagttca agggtctccg tcagcaggcg ggtatccaca gactcaccgg cagcgtgagc
    82441 acgcatggcc gcgagcgcca cctcctcggt gaacatgtac ggcggggtgc ggcggtgttt
    82501 acccggcatg gtcagaccgt acttcagggc ataacgggca atctccagcg caccggcaat
    82561 atcgccagta tccagacgcc acagcatgac cgtcatcaga atgtcatcct gtgcaccttt
    82621 gccctgctcc agcacgccgt tcacccacgg caaccagaac ggcagcagtt cgcgtttttt
    82681 cgcggccttc agctcttttg aataaatcgc tttcagtgtg cgctggtctg cggccagctt
    82741 gaccagcatc tgctcataga cagttgcatg tcgcagcggg gcggcttccc gctgcgcggt
    82801 catcgctgcc gagacccgca tcatgtggcg ctgtgcggga ctcgtcatcg gttacgctcc
    82861 cggctctgcg gtcgctttag ccggtgtgga gaaatcaccg accttaattt tttccaccag
    82921 acaaccggcg gcgtagtcct ccaccacgta atcaatgttc attgactcgt agttctccac
    82981 gcggtcgagt ttcgggtttt ccacaatcac gcggcgatgg ctgtcatcca tgtagtagat
    83041 ggacaggttt tccagcttcg tgatgagcat cgcatccgcc gggaagtacg ggacgcgtac
    83101 cgccggcagg ttaccgatgc gtttctggct gataatgacg tcagcggcca gcatctcgct
    83161 gttgtcctgc tccttgttga cgatggggaa atacttgtcc gccagtagct gacgccccac
    83221 aatcaccaca aggtcagggt cttcctgata ccacggctca atcaggttgt tggtcgcatc
    83281 catcaccagt gcatcgaggc tggcataatc accgccctta cccacgcgga tgacctcaga
    83341 ggtcgtgtga ccttcctcgt cagtaacctt gctcatcacg cgcgccgggg cttcattgcg
    83401 gtatttctgc agccagccga ccgccacatc ctgcagcatc tggttactgc tgcggtcaga
    83461 ggtttcggca cgcctcacgc cgttaaaacc ggccatgatg aaatcaaggg actggcgttt
    83521 gataatggcg ttacggacac ggagctggaa atcctgataa cgcgcccaca ggtcaagcgt
    83581 tttgtagcgg atataaaaat cgaagttaat ctggtcgcat tcgtacttac tggacgccag
    83641 cttcgagaag tccttcggct gacgctcggt gccaccggcg gtgtcggtgg tgctggcgat
    83701 ggagccggtg acaccaatac caattttttc ccctttcatt tcgctgaccg gcacaatgtt
    83761 gatgcgggtc agaaaatcag aggactcctg catggtgttc atcagggtct gggtgaccga
    83821 cggttcaacg gtgaattttt tcgacacatc accggcgtcg atgccgttca gttcggcaac
    83881 acgggacagg taggcattaa atttaaagcg ggtttcctgg cgcatagttt ttcctgaaat
    83941 taagggttaa tcgtgaaggt tttcccggac tgactgacgc cggtcagcag ttcgtcatca
    84001 gggcgtcacc gccaccaccg gtggccttgc tgcggcgctg ctgggtcaga ctttcggtgt
    84061 ggtcgagact gtttttcagg cgggtgaatg cctggctggt ttcatccgcc ctgtcagtca
    84121 catcctgctt aagtgcggaa aaggcggttt ccatctcagc gaggcgctgc tcagtggcgc
    84181 tcagtttttc ctgcacatgt tcagcaacag cggtcaccgc ttcatgcacg tcattcagac
    84241 gggcgtcatc gctggcctgt ttgcggccaa aaatggattt caccttttcg gtcagggcgg
    84301 tgaacacggt ttcaggcagg tcttcaaatt ccagctcaac aggcgttgcc actgaaatca
    84361 ggttttcagg gcttaatttg aagcggttca gggggttgtg ttttgccgtg cggcagaatt
    84421 ccaggtattc cgtgccgagg cttgccgggt catcggtgac ggccagaccc accagataac
    84481 atttgccggt attggcaaag ttcggctgaa tttccattga ggtatagacc ttctgcgcgg
    84541 ccttgttcat cgcgataagg tcatcggtcg gggtgatttt cgcaaacagc gcccattt
//
LOCUS       DAPOXO010000008        79612 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPOXO010000008 DAPOXO010000000
VERSION     DAPOXO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 79612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79612
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.008"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            112..372
                     /gene="iraP"
                     /locus_tag="ROH59_000746"
     CDS             112..372
                     /gene="iraP"
                     /locus_tag="ROH59_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HDX4803268.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLRHPRQ"
     gene            473..1888
                     /gene="phoA"
                     /locus_tag="ROH59_000747"
     CDS             473..1888
                     /gene="phoA"
                     /locus_tag="ROH59_000747"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HDX4803269.1"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKP
                     LLGLFADGNMPVRWQGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            2007..2327
                     /gene="psiF"
                     /locus_tag="ROH59_000748"
     CDS             2007..2327
                     /gene="psiF"
                     /locus_tag="ROH59_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HDX4803270.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            2429..3544
                     /gene="adrA"
                     /locus_tag="ROH59_000749"
                     /gene_synonym="dgcC"
     CDS             2429..3544
                     /gene="adrA"
                     /locus_tag="ROH59_000749"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HDX4803271.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(3561..4370)
                     /gene="proC"
                     /locus_tag="ROH59_000750"
     CDS             complement(3561..4370)
                     /gene="proC"
                     /locus_tag="ROH59_000750"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDX4803272.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVTA
                     LHEQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGITL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGTLKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            4490..4948
                     /locus_tag="ROH59_000751"
     CDS             4490..4948
                     /locus_tag="ROH59_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDX4803273.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     gene            5131..5655
                     /gene="aroL"
                     /locus_tag="ROH59_000752"
     CDS             5131..5655
                     /gene="aroL"
                     /locus_tag="ROH59_000752"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HDX4803274.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     gene            5705..5896
                     /gene="yaiA"
                     /locus_tag="ROH59_000753"
     CDS             5705..5896
                     /gene="yaiA"
                     /locus_tag="ROH59_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HDX4803275.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            6154..6831
                     /locus_tag="ROH59_000754"
     CDS             6154..6831
                     /locus_tag="ROH59_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HDX4803276.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLM"
     gene            6903..7187
                     /gene="ppnP"
                     /locus_tag="ROH59_000755"
     CDS             6903..7187
                     /gene="ppnP"
                     /locus_tag="ROH59_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDX4803277.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            7335..7676
                     /locus_tag="ROH59_000756"
                     /pseudo
     CDS             7335..7676
                     /locus_tag="ROH59_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308469.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing protein"
     gene            7673..7753
                     /locus_tag="ROH59_000757"
     CDS             7673..7753
                     /locus_tag="ROH59_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803278.1"
                     /translation="MTQRPWSKLQHKTHNIAALRIIARCS"
     gene            complement(7834..8745)
                     /gene="rdgC"
                     /locus_tag="ROH59_000758"
     CDS             complement(7834..8745)
                     /gene="rdgC"
                     /locus_tag="ROH59_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HDX4803279.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQVRKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            8870..9778
                     /gene="mak"
                     /locus_tag="ROH59_000759"
     CDS             8870..9778
                     /gene="mak"
                     /locus_tag="ROH59_000759"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308471.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HDX4803280.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVPQLIKQFVFGGE
                     CETPVHKAKHGDSSGVRGAAWLWPQE"
     gene            complement(10047..11231)
                     /gene="araJ"
                     /locus_tag="ROH59_000760"
     CDS             complement(10047..11231)
                     /gene="araJ"
                     /locus_tag="ROH59_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HDX4803281.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAIFNIAVMASVYFWVPDIRDEAKGKLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFFGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADSPVLAKP
                     LG"
     gene            complement(11357..14500)
                     /gene="sbcC"
                     /locus_tag="ROH59_000761"
     CDS             complement(11357..14500)
                     /gene="sbcC"
                     /locus_tag="ROH59_000761"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HDX4803282.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKDEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
                     QSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRLDELQQEASRRQQALQQALAEEEQA
                     QPQLAALSLAQPARNLRPHWERIAEHSTALAHTRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNAWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVASAQAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQ
                     NVTLEQTQRNAALNKMRHRYKEKMQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQARLLTLEKEVKKLGEEGATLRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRMQQLTPILETLPQSDELPHSEETVALENWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLTQHQQHRPGGLSLTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESAFAVK"
     gene            complement(14497..15699)
                     /gene="sbcD"
                     /locus_tag="ROH59_000762"
     CDS             complement(14497..15699)
                     /gene="sbcD"
                     /locus_tag="ROH59_000762"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HDX4803283.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQAHLVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQLIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFATTLH
                     SLAGEHEA"
     gene            15889..16578
                     /gene="phoB"
                     /locus_tag="ROH59_000763"
     CDS             15889..16578
                     /gene="phoB"
                     /locus_tag="ROH59_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HDX4803284.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            16636..17931
                     /gene="phoR"
                     /locus_tag="ROH59_000764"
     CDS             16636..17931
                     /gene="phoR"
                     /locus_tag="ROH59_000764"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HDX4803285.1"
                     /translation="MLERLSWKRLVLELLFCCLPAFILGAFLGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFIIPERLIAKNSD"
     gene            18338..19657
                     /gene="brnQ"
                     /locus_tag="ROH59_000765"
     CDS             18338..19657
                     /gene="brnQ"
                     /locus_tag="ROH59_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HDX4803286.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIIWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            19733..21106
                     /gene="proY"
                     /locus_tag="ROH59_000766"
     CDS             19733..21106
                     /gene="proY"
                     /locus_tag="ROH59_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HDX4803287.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            21262..23079
                     /gene="malZ"
                     /locus_tag="ROH59_000767"
     CDS             21262..23079
                     /gene="malZ"
                     /locus_tag="ROH59_000767"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308480.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HDX4803288.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVPMHKQRSQPQPGVTAWRAAIELSCGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARQEQFAIDVPDIGPQWAADQIFYQIFPDRFARNLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNTQQLGIRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNLQHVAGITEAAKETQPDAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDVARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     SALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWMN"
     gene            complement(23084..23665)
                     /gene="acpH"
                     /locus_tag="ROH59_000768"
     CDS             complement(23084..23665)
                     /gene="acpH"
                     /locus_tag="ROH59_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HDX4803289.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRNETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFT
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQSVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMEQASRKAL"
     gene            23758..24828
                     /gene="queA"
                     /locus_tag="ROH59_000769"
     CDS             23758..24828
                     /gene="queA"
                     /locus_tag="ROH59_000769"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDX4803290.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDQRSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            24883..26010
                     /gene="tgt"
                     /locus_tag="ROH59_000770"
     CDS             24883..26010
                     /gene="tgt"
                     /locus_tag="ROH59_000770"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDX4803291.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     gene            26033..26365
                     /gene="yajC"
                     /locus_tag="ROH59_000771"
     CDS             26033..26365
                     /gene="yajC"
                     /locus_tag="ROH59_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDX4803292.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            26393..28240
                     /gene="secD"
                     /locus_tag="ROH59_000772"
     CDS             26393..28240
                     /gene="secD"
                     /locus_tag="ROH59_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HDX4803293.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPSEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            28251..29222
                     /gene="secF"
                     /locus_tag="ROH59_000773"
     CDS             28251..29222
                     /gene="secF"
                     /locus_tag="ROH59_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HDX4803294.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            29352..29699
                     /locus_tag="ROH59_000774"
     CDS             29352..29699
                     /locus_tag="ROH59_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HDX4803295.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(29737..30621)
                     /gene="tsx"
                     /locus_tag="ROH59_000775"
     CDS             complement(29737..30621)
                     /gene="tsx"
                     /locus_tag="ROH59_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HDX4803296.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQLRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKVKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGYANNGIKTRTNNSIASSHILALNYDHWHYSVVARYWHNGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(30920..31459)
                     /locus_tag="ROH59_000776"
     CDS             complement(30920..31459)
                     /locus_tag="ROH59_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HDX4803297.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     KETVKITQQNKLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDTDGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     gene            31610..32059
                     /gene="nrdR"
                     /locus_tag="ROH59_000777"
     CDS             31610..32059
                     /gene="nrdR"
                     /locus_tag="ROH59_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HDX4803298.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     gene            32063..33166
                     /gene="ribD"
                     /locus_tag="ROH59_000778"
     CDS             32063..33166
                     /gene="ribD"
                     /locus_tag="ROH59_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDX4803299.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQGL
                     YPQQNLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGNDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            33255..33725
                     /gene="ribE"
                     /locus_tag="ROH59_000779"
     CDS             33255..33725
                     /gene="ribE"
                     /locus_tag="ROH59_000779"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDX4803300.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            33745..34164
                     /gene="nusB"
                     /locus_tag="ROH59_000780"
     CDS             33745..34164
                     /gene="nusB"
                     /locus_tag="ROH59_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDX4803301.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            34242..35219
                     /gene="thiL"
                     /locus_tag="ROH59_000781"
     CDS             34242..35219
                     /gene="thiL"
                     /locus_tag="ROH59_000781"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HDX4803302.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     gene            35197..35715
                     /gene="pgpA"
                     /locus_tag="ROH59_000782"
     CDS             35197..35715
                     /gene="pgpA"
                     /locus_tag="ROH59_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDX4803303.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVTAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAVILY
                     FIGHHWPLGILS"
     gene            complement(35769..36743)
                     /gene="yajO"
                     /locus_tag="ROH59_000783"
     CDS             complement(35769..36743)
                     /gene="yajO"
                     /locus_tag="ROH59_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HDX4803304.1"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKVGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGKNLYQESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     gene            complement(36798..38660)
                     /gene="dxs"
                     /locus_tag="ROH59_000784"
     CDS             complement(36798..38660)
                     /gene="dxs"
                     /locus_tag="ROH59_000784"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDX4803305.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDATGMEAKIKAWLA"
     gene            complement(38685..39584)
                     /gene="ispA"
                     /locus_tag="ROH59_000785"
     CDS             complement(38685..39584)
                     /gene="ispA"
                     /locus_tag="ROH59_000785"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HDX4803306.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LTEQSFDTSALEALADYIIQRNK"
     gene            complement(39584..39826)
                     /gene="xseB"
                     /locus_tag="ROH59_000786"
     CDS             complement(39584..39826)
                     /gene="xseB"
                     /locus_tag="ROH59_000786"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDX4803307.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            40032..41480
                     /gene="thiI"
                     /locus_tag="ROH59_000787"
     CDS             40032..41480
                     /gene="thiI"
                     /locus_tag="ROH59_000787"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDX4803308.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSK
                     NWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            complement(41534..42124)
                     /gene="yajL"
                     /locus_tag="ROH59_000788"
     CDS             complement(41534..42124)
                     /gene="yajL"
                     /locus_tag="ROH59_000788"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HDX4803309.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(42087..42998)
                     /gene="panE"
                     /locus_tag="ROH59_000789"
     CDS             complement(42087..42998)
                     /gene="panE"
                     /locus_tag="ROH59_000789"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDX4803310.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHDVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            43166..43657
                     /gene="yajQ"
                     /locus_tag="ROH59_000790"
     CDS             43166..43657
                     /gene="yajQ"
                     /locus_tag="ROH59_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HDX4803311.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            complement(43785..45149)
                     /locus_tag="ROH59_000791"
     CDS             complement(43785..45149)
                     /locus_tag="ROH59_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803312.1"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHVLFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQMADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
                     YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEVEQA
                     IRQA"
     gene            complement(45298..46188)
                     /gene="cyoE"
                     /locus_tag="ROH59_000792"
     CDS             complement(45298..46188)
                     /gene="cyoE"
                     /locus_tag="ROH59_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HDX4803313.1"
                     /translation="MIFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            complement(46200..46529)
                     /locus_tag="ROH59_000793"
     CDS             complement(46200..46529)
                     /locus_tag="ROH59_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HDX4803314.1"
                     /translation="MSHSNASSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQILVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(46529..47143)
                     /locus_tag="ROH59_000794"
     CDS             complement(46529..47143)
                     /locus_tag="ROH59_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HDX4803315.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            complement(47133..49124)
                     /gene="cyoB"
                     /locus_tag="ROH59_000795"
     CDS             complement(47133..49124)
                     /gene="cyoB"
                     /locus_tag="ROH59_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HDX4803316.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQIYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            complement(49146..50093)
                     /gene="cyoA"
                     /locus_tag="ROH59_000796"
     CDS             complement(49146..50093)
                     /gene="cyoA"
                     /locus_tag="ROH59_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HDX4803317.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNSMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            complement(50553..52028)
                     /gene="ampG"
                     /locus_tag="ROH59_000797"
     CDS             complement(50553..52028)
                     /gene="ampG"
                     /locus_tag="ROH59_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HDX4803318.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTEYPAGYAFAMWTLAAGISLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            complement(52072..52650)
                     /locus_tag="ROH59_000798"
     CDS             complement(52072..52650)
                     /locus_tag="ROH59_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX4803319.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            52955..53272
                     /gene="bolA"
                     /locus_tag="ROH59_000799"
     CDS             52955..53272
                     /gene="bolA"
                     /locus_tag="ROH59_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HDX4803320.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            53616..54914
                     /gene="tig"
                     /locus_tag="ROH59_000800"
     CDS             53616..54914
                     /gene="tig"
                     /locus_tag="ROH59_000800"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDX4803321.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTEEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            55160..55783
                     /gene="clpP"
                     /locus_tag="ROH59_000801"
     CDS             55160..55783
                     /gene="clpP"
                     /locus_tag="ROH59_000801"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDX4803322.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            55909..57183
                     /gene="clpX"
                     /locus_tag="ROH59_000802"
     CDS             55909..57183
                     /gene="clpX"
                     /locus_tag="ROH59_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HDX4803323.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            57371..59725
                     /gene="lon"
                     /locus_tag="ROH59_000803"
     CDS             57371..59725
                     /gene="lon"
                     /locus_tag="ROH59_000803"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDX4803324.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            59934..60206
                     /gene="hupB"
                     /locus_tag="ROH59_000804"
     CDS             59934..60206
                     /gene="hupB"
                     /locus_tag="ROH59_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HDX4803325.1"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            60398..62269
                     /gene="ppiD"
                     /locus_tag="ROH59_000805"
     CDS             60398..62269
                     /gene="ppiD"
                     /locus_tag="ROH59_000805"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDX4803326.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREAAIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            62420..62791
                     /locus_tag="ROH59_000806"
     CDS             62420..62791
                     /locus_tag="ROH59_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDX4803327.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAAPAAKPTTVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNMAVLTL"
     gene            62909..63307
                     /gene="fadM"
                     /locus_tag="ROH59_000807"
     CDS             62909..63307
                     /gene="fadM"
                     /locus_tag="ROH59_000807"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HDX4803328.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWHGLENSDSFHWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(63359..64054)
                     /gene="queC"
                     /locus_tag="ROH59_000808"
     CDS             complement(63359..64054)
                     /gene="queC"
                     /locus_tag="ROH59_000808"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HDX4803329.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLK"
     gene            complement(64119..65819)
                     /locus_tag="ROH59_000809"
     CDS             complement(64119..65819)
                     /locus_tag="ROH59_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HDX4803330.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTVL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSLRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LLAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQVMPDEE
                     NRFNALKAVFSQLMADATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            65919..66737
                     /gene="cof"
                     /locus_tag="ROH59_000810"
     CDS             65919..66737
                     /gene="cof"
                     /locus_tag="ROH59_000810"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HDX4803331.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            66890..67348
                     /gene="decR"
                     /locus_tag="ROH59_000811"
     CDS             66890..67348
                     /gene="decR"
                     /locus_tag="ROH59_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HDX4803332.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            67378..69150
                     /locus_tag="ROH59_000812"
     CDS             67378..69150
                     /locus_tag="ROH59_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDX4803333.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFALLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRTMLAEAPVVIDGSDKVPEGRGE
                     LDVNIRQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLVQQSGWYRD
                     MYRYQQLEAALDDAPEIREEAVDA"
     gene            69143..70924
                     /locus_tag="ROH59_000813"
     CDS             69143..70924
                     /locus_tag="ROH59_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDX4803334.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     SLQSGTIDVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSTLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTLLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            71105..71443
                     /gene="glnK"
                     /locus_tag="ROH59_000814"
     CDS             71105..71443
                     /gene="glnK"
                     /locus_tag="ROH59_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDX4803335.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            71473..72759
                     /gene="amtB"
                     /locus_tag="ROH59_000815"
     CDS             71473..72759
                     /gene="amtB"
                     /locus_tag="ROH59_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HDX4803336.1"
                     /translation="MKIATIKTGLTSLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNING
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(72808..73668)
                     /gene="tesB"
                     /locus_tag="ROH59_000816"
     CDS             complement(72808..73668)
                     /gene="tesB"
                     /locus_tag="ROH59_000816"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HDX4803337.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPDERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            73886..74458
                     /locus_tag="ROH59_000817"
     CDS             73886..74458
                     /locus_tag="ROH59_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HDX4803338.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            complement(74489..74800)
                     /locus_tag="ROH59_000818"
     CDS             complement(74489..74800)
                     /locus_tag="ROH59_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HDX4803339.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQLYRWN
                     Y"
     gene            74963..75059
                     /gene="ffs"
                     /locus_tag="ROH59_000819"
     ncRNA           74963..75059
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ROH59_000819"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            75179..75532
                     /locus_tag="ROH59_000820"
     CDS             75179..75532
                     /locus_tag="ROH59_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 family protein"
                     /protein_id="HDX4803340.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DIPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(75574..77124)
                     /gene="pdeB"
                     /locus_tag="ROH59_000821"
     CDS             complement(75574..77124)
                     /gene="pdeB"
                     /locus_tag="ROH59_000821"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HDX4803341.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDELAQGIITRLQKTPGEHIENNGIIYDILP
                     LPEMNISIITWASTKMLQKGWYRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(77288..77758)
                     /locus_tag="ROH59_000822"
     CDS             complement(77288..77758)
                     /locus_tag="ROH59_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaC family protein"
                     /protein_id="HDX4803342.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     gene            complement(77874..78425)
                     /gene="maa"
                     /locus_tag="ROH59_000823"
     CDS             complement(77874..78425)
                     /gene="maa"
                     /locus_tag="ROH59_000823"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HDX4803343.1"
                     /translation="MSTEKEKMIAGELYHSADEALSRDRLRARRLIHRYNHSLAEEHT
                     LRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     APGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
                     VVTKDVPDNVVVGGNPARIIKKL"
     gene            complement(78599..78817)
                     /gene="hha"
                     /locus_tag="ROH59_000824"
     CDS             complement(78599..78817)
                     /gene="hha"
                     /locus_tag="ROH59_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDX4803344.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            complement(78843..79217)
                     /gene="tomB"
                     /locus_tag="ROH59_000825"
     CDS             complement(78843..79217)
                     /gene="tomB"
                     /locus_tag="ROH59_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HDX4803345.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
BASE COUNT        19361 a        19697 c        21298 g        19256 t
ORIGIN      
        1 aaaatatttg cgcaaagtat ttcctttgtc ataaaaataa tacttccaga cactatgaag
       61 ttgtgaaaca taatgttaac ttctccatac tttggataag gaaatacaga catgaaaaat
      121 ctcattgctg agttgttatt taagcttgcc caaaaagaag aagagtcgaa agaactgtgt
      181 gcgcaggtag aagctttgga gattatcgtc acggcaatgc ttcgcaatat ggcgcaaaat
      241 gatcaacagc ggttgattga tcaggtagag ggggcgctgt acgaggtaaa gcccgatgcc
      301 agcattcctg acgacgatac ggagctgctg cgcgattacg taaagaagtt attgaggcat
      361 cctcgtcagt aaaaagttaa tcttttcaac agctgtcata aagttgtcac ggccgagact
      421 tatagtcgct ttgtttttat tttttaatgt atttgtacat ggagaaaata aagtgaaaca
      481 aagcactatt gcactggcac tcttaccgtt actgtttacc cctgtgacaa aagcccggac
      541 accagaaatg cctgttctgg aaaaccgggc agctcagggc gatattactg cacccggcgg
      601 tgctcgccgc ttaacgggtg atcagaccgc tgctctgcgt gattctctta gcgataaacc
      661 tgcaaaaaat attattttgc tgattggcga tgggatgggg gactcggaaa ttactgccgc
      721 acgcaattat gccgaaggtg cgggcggctt ttttaaaggt atcgatgcct taccgcttac
      781 cgggcaatac actcactatg cgctgaataa aaaaaccggc aaaccggact acgtcaccga
      841 ctcggctgca tcagcaaccg cctggtcaac tggtgtcaaa acctataacg gcgcgctggg
      901 cgtcgatatt cacgaaaaag atcacccaac gattctggaa atggcaaaag ccgcaggtct
      961 ggcgaccggt aacgtttcta ccgcagagtt gcaggatgcc acgcccgctg cgctggtggc
     1021 gcatgtgacc tcgcgcaaat gctacggtcc aagtgcgacc agtgaaaaat gtccgggtaa
     1081 cgctctggaa aaaggcggaa aaggatcgat taccgaacag ctgcttaacg cccgtgccga
     1141 tgttacgctt ggcggcggtg caaaaacctt tgctgaaacg gcaaccgccg gtgaatggca
     1201 gggaaaaacg ctgcgtgaac aggcacaggc gcgtggttat cagttggtga gcgatgctgc
     1261 ctcactgaat tcggtgacgg aagcgaatca gcaaaaaccc ctattaggac tgtttgctga
     1321 cggcaatatg ccagtgcgct ggcaaggacc gaaagcaacg taccacggta atatagataa
     1381 gcccgcagtc acctgtacgc ctaatccgca acgtaatgac agtgtaccga ccctggcgca
     1441 gatgaccgac aaagccattg aattgttgag taaaaatgag aaaggctttt tcctgcaagt
     1501 tgaaggtgcg tcaatcgata aacaggatca cgctgcgaat ccttgtgggc aaattggcga
     1561 gacggtcgat ctcgatgaag ccgtacaacg ggcgctggaa ttcgctaaaa aggatggtaa
     1621 cacgttggtc atagtcaccg ctgatcacgc ccatgccagc cagatagttg cgccagatac
     1681 caaagctccg ggcctcaccc aggcgctaaa taccaaagat ggcgcagtga tggtgatgag
     1741 ttacgggaac tccgaagagg attcacaaga acataccggc agtcagttgc gtattgcggc
     1801 gtatggcccg catgccgcca atgttgttgg actgaccgac cagaccgatc tcttctacac
     1861 catgaaagcc gccctggggc tgaaataaaa ccgcgcccgg cagtgaattt tcgctgccgg
     1921 gtggtttttt tgctgttagc aaccagactt aatgacagat cacgggcgca tacgctcatg
     1981 gttaaaacat gaagagggat ggtgcgatga aaattacatt actggttacc ttgcttttcg
     2041 gtctggtttt tttaaccacc gtcggcgctg ccgagagaac cttaacccca caacaacagc
     2101 gtatgacctc ttgtaatcag caggcgacgg cgcaggcgtt gaaaggggat gctcgtaaga
     2161 cctacatgag tgattgcctg aagaacagca aatctgcgcc tggtgaaaaa agtttgacgc
     2221 cacagcagca aaagatgcgc gaatgtaata atcaagcaac acaacaatct ctgaaagggg
     2281 atgatcgtaa taagtttatg agtgcctgcc tcaagaaagc cgcctgatac ctgatagtgc
     2341 taacgggtga gctacgaaaa tggctcaccc gaaatttcat acttctgcct ttagtcccgt
     2401 ctctataatt tgggaaaatt gtttctgaat gttcccaaaa ataatgaatg atgaaaactt
     2461 tttcaaaaaa gcggcggcgc atggggagga acctccttta actcctcaaa acgaacatca
     2521 gcggtccggg ctgcgcttcg cccgtcgcgt cagactaccc cgcgcggttg gtctggctgg
     2581 catgttctta ccgattgctt caacgctggt ttcgcacccg ccgccgggct ggtggtggct
     2641 ggtgttggtc ggctgggcgt tcgtctggcc gcatttagcc tggcagatag cgagcagggc
     2701 cgtcgatccg cttagccggg aaatttacaa cttaaaaacc gatgcagtat tagcgggaat
     2761 gtgggtaggc gtaatgggcg taaacgtgct gccttccacc gcgatgttga tgattatgtg
     2821 tctgaatttg atgggggcag gcggcccccg tctgtttgtt gcgggtctgg tgttgatggt
     2881 ggtttcctgc cttgtcaccc tcgaactgac gggcatcacc gtgtcgttca atagcgcacc
     2941 gctggaatgg tggctctccc ttcccattat tgtcatttat cctctgctgt ttggctgggt
     3001 cagctaccag acggcgacta aactggcgga acataaacgc aggttgcagg tcatgagtac
     3061 ccgcgacggt atgacgggcg tgtataacag acgtcattgg gaaactatgt tacgcaatga
     3121 atttgataac tgtcggcggc ataatcgcga tgcaacgtta ctgattatcg atatcgacca
     3181 tttcaagagc atcaacgata cctggggcca tgatgtgggt gatgaagcga ttgtggcgct
     3241 tacccgacag ttacaaatta ccctgcgcgg tagcgatgtg attggtcggt ttggcggcga
     3301 tgagtttgca gtaatcatgt ccggtacgcc agctgagagc gccatcaccg ccatgttacg
     3361 ggtgcatgaa gggctaaaca cgttacgctt gccgaatacg ccacaggtaa ctttacggat
     3421 tagtgtgggg gttgcgccgc tgaatccaca aatgagtcac tatcgcgagt ggttgaaatc
     3481 ggcagatttg gcgctctaca aagcaaagaa agccggacgt aaccgcaccg aagtggcggc
     3541 ctgacgtccg gcaaaagcca tcaggatttg ctgagttttt ctgatttttc catacacttc
     3601 gtcatcgctt cgatcactgc ggcacggaag cctttctctt ccagtacgcg taccgcctca
     3661 atggtggtgc ctcccggtga gcagaccata tctttcagtg ttcccggatg ttctcccgtt
     3721 tccagcacca tttttgcgga gcccattacc gcctgagcgg caaatttata cgcctgggcg
     3781 cgtggcatcc cgcccagcac ggcggcgtcg gccatcgctt cgataaacat aaagacgtag
     3841 gctggcgaag aaccgctcac accgaccacc gggtggatca tcggctcagc aatcacttcc
     3901 gcttcgccaa agcagcggaa aatattcagc acatcagcgg tatcttctgg ggttaccagc
     3961 gcgtttggcg ttacggaggt catcccggca ttaaccagcg cgggagtgtt cggcatggcg
     4021 cggataattt tccggtcatg gcccagcgcg cgggcaagct ggtcgagcgt gatacctgca
     4081 gcaatagaaa cgaccagaga gtctttattc aggctggagg tgatttcgct aagcacttta
     4141 atcatgatgc ctggtttaac ggcggcaaaa atgatgtcgg cgatttgcgc tacttcttgc
     4201 gccgattctg cggcgttgat gccgaactgt tcatgcaggg cggtgacttt atccggggag
     4261 ggggtatata cccagatttg ccctggaagc acctgaccgc tggcaatcag accgccgaga
     4321 atggcttttc ccatattgcc gcagccaata aaaccgattt tcttttccat tgcctcactc
     4381 ctgccgtgaa attcattgtt ttgataatcg ctggcagaag cataaacaga actatgccgg
     4441 aaggcaaaag cgcgacacaa tagaggatta cccaacaaag gatgacttta tgacaatttg
     4501 ggtggatgcc gacgcgtgtc ccaatgtaat taaagagatt ttgtatcgcg cggcggaacg
     4561 tatgcagatg ccgctggtac tggtagcaaa ccagagttta cgcgtgccgc catcacgatt
     4621 tattcgtacg ctgcgcgtcg cggcaggttt cgacgttgcc gataacgaaa ttgttcggca
     4681 gtgtgaagcg ggcgatttgg tgatcaccgc agatatacct ttggctgctg aagccattga
     4741 gaaaggcgcg gcggcgctta atccgcgcgg cgaacgttat acgccagcga ccattcgtga
     4801 gcgcctgacg atgcgcgatt ttatggatac cttacgtgcc agtgggatcc agaccggagg
     4861 accagatagt ctttcacaac gtgaccgcca ggcttttgct gcggagctgg agaagtggtg
     4921 gctggaagtg caacgtagtc gtggctaaat gtaatttatt atttacactt cattcttgaa
     4981 tatttattgg tatagtaagg gatgtattga gattttcact ttaagtggaa ttttttcttt
     5041 acaatcgaaa ttgtactagt ttgatggtat gatcgccatt ctcatgacac cggctttcgc
     5101 cgcattgcga cctattgggg aaaacccacg atgacacaac ctctttttct gatcgggcct
     5161 cggggctgtg gtaaaacaac ggtcggaatg gcccttgccg attcgcttaa ccgtcggttt
     5221 gtcgataccg accagtggtt gcaatcacag ctcaatatga cggtcgcgga gatcgtcgaa
     5281 agggaagagt gggcgggatt ccgcgccaga gaaacggcgg cactggaagc ggtaactgcg
     5341 ccatccaccg ttatcgccac gggcggcggc attattctga cggaatttaa tcgtcacttc
     5401 atgcaaaata acgggatcgt ggtttatttg tgtgcgccag tatcagtcct ggttaaccga
     5461 ctgcaagctg caccggaaga agatttacgg ccaaccttaa cgggaaaacc actgagcgaa
     5521 gaagttcagg aagtgctgga agaacgcgat gcgctatatc gcgaagttgc gcatattatc
     5581 atcgacgcaa caaacgaacc cagccaggtg atttctgaaa ttcgcagcgc tctggcacag
     5641 acgatcaatt gttgattttc gagcgcctat acttaacgtt catcccgtga aataaggaag
     5701 aacgatgcca acgaaaccgc cttatcctcg tgaagcatat atagtgacga ttgaaaaagg
     5761 aaagccagga cagacggtaa cctggtacca actcagagcc gatcatccta aaccagactc
     5821 gttgatcagt gaacatccga ccgctcagga agcgatggat gcgaaaaaac gctatgagga
     5881 ccctgacaaa gagtgaccgc atcagaccgc tcggaaggga ttctgagtgc cgccacaagg
     5941 gatctgcgtc acatttttca caattcatgt ttttcaaata attagaatat taaacaataa
     6001 caatccatta ctggaatcat ttggaatctt tacattatgc agtgcaggtc tgctgctacg
     6061 ctttttgtca tttgtagcac aagtaagtgt cagcagtggt gcttaacact tgcccggtaa
     6121 ttaacgacga aataaaagta aggtggaaga acaatgagtg cgtcgttggc gatcctgact
     6181 atcggcattg tacctatgca ggaagttttg ccgctcctga cagaatacat tgacgaagat
     6241 aatatttccc atcatagcct gctggggaag ttaagccgcg aagaagtgat ggcggagtac
     6301 gcgccagaag caggcgaaga cacaattctc acattattaa atgacaacca tctggcccat
     6361 gtttcgcgtc gcaaagttga gcgagacctg caaggtgtgg ttgaagtgct cgataatcag
     6421 ggttacgacg tcattatatt aatgagtaca gcaaacatta gtagtatgac cgcgcgtaat
     6481 acgatctttc ttgagccgtc gcggatattg ccaccgctgg tttcctctat tgttgaagat
     6541 catcaggtgg gggttatcgt accggttgag gagttgctga ccgttcaggc gcaaaaatgg
     6601 caaattttgc agaaaccgcc agtattttca ttgggtaacc ccattcatga ttcggaacaa
     6661 aaaatcattg atgccgggaa agaattactg gcaaaaggtg cagatgtcat catgctggat
     6721 tgtttgggat ttaaccagcg tcatcgcgat ttactgcaaa aacagctcga tgttcctgtc
     6781 ttgctctcta acgtattgat tgcacggctg gctgcggaat tactgatgta attttgcgtg
     6841 acagccagcg cctctggccc ctatagtgaa gtagatgttc aactaccaga cagggccagt
     6901 ttatgcttca aagtaatgag tacttttccg gcaaagtgaa atcgatcggc ttttccagca
     6961 gcagcactgg tcgcgccagc gtgggtgtta tggttgaagg tgaatacacc ttcagcaccg
     7021 ctgagcctga agagatgacg gtaatcagtg gcgcgctgaa tgtgttactg cctgacgcga
     7081 ccgactggca agtgtatgaa gccggttcgg tgtttaatgt tcccggtcac agcgagtttc
     7141 atctgcaagt tgccgaaccc acctcttatc tgtgccgcta tctgtaattc ctcgccttcc
     7201 ccttgaacgg gagggcattt ttctgaaatg tcctctcttt aacccataat aatatttcct
     7261 ttgctgggat tttttcgatt tccgatatat tcataattca tcaaggttga tatcaatatc
     7321 agcgaagatc tccagatatt gttgcggaac tggcgacgat aaaagataaa tcagatgatg
     7381 aatggtggcg tgcattgctg caaagtcgca atgatcattt gcgccaaacg gcattgcaca
     7441 acgcacatac cccggtgttg ttgttaacga cattgactga gcctcaggag cggtcgctgg
     7501 ctattaataa ttcacagctg gctgccgatg tgaaaacggc gtggttaaaa gaggatccat
     7561 cattactctt atttgtcgaa caacccgatc tttcgctgtt acgtgattta gtgaaaaccg
     7621 gggcaacgcg aaaaattcgc agtgaagcgc gtcaccggct tgaggaaaaa caatgacaca
     7681 acgcccctgg agcaagttac agcataaaac gcataatatt gctgcgctaa gaattattgc
     7741 ccgctgtagc taacgattat attcctggtg tggcttcgta cgccggataa gacgcggcag
     7801 gcgtcgcatc cggcattaaa ggtaaatcag caattaacgt tgtgcttcgc cacctaatcc
     7861 ttcaatcagg ttttgaatta acgctgccag ttcaccagtc atcaggatga aatcggcatc
     7921 aaagcgctgg gcgaaatctt cacggtcgat atcttcgttt tgatcgcgca gctcgtcgca
     7981 gaacttcaga cgcttgagcg aaccatcgtc gcacatcaca aactgaatgc gctgctgcca
     8041 gtcgagcgcc agtttagtca ccacttttcc ggcttcaatg tggttggtga tctcttcgct
     8101 ggtcagatct tgtttcttcg cgcggatcac gccgccatct tccagcaacg atttcagctc
     8161 ggcttcatca agcagctgga agccctgtgc cgcgctgccg gaacgtaccc attcggtcag
     8221 cgtcagttca atcgggtttt ccatgctcaa tggtacaacc ggtaacgacc ccaggctttt
     8281 acgcagcagt gccagcgtat cttccgcttt tttggcgctg gcgcagtcca ccataatcaa
     8341 accgttaacc gtatcgatcc acatcattgt ctggctaaaa cggctgaaag cacgcggcag
     8401 cagagagtgc agcacttcgt ctttcagcga atctttttcg gttttcttca gcttacgcac
     8461 ctgttccgct tccagtttgg cgattttcgc ttccagcgcc tgtttaatca ccggggacgg
     8521 gaggattttt tcttctttgc gcgcacagat aacaatttga ccattggcaa cgtgcgttaa
     8581 cgcatcgctg tgcgatccca tcggaggtac ccagcccatc ttcgccatgt cctggctgcc
     8641 gcatggggta aatgccatcg aggctagctg tttttccatc tcttctgcac gcagcgaaat
     8701 ctcgcggcta agacggtaaa ccattaaatt tttgaaccac agcatgataa tttccacggc
     8761 cttgtcgtta aatttagcgg gcatgataac gaattgtcgg cggccttgca ttgccaatcc
     8821 ggttgtccgt ctctacgcta ttgatattga aaaaaataag gagagtaccg tgcgtatagg
     8881 tatcgattta ggcggcacca aaactgaagt gattgcattg ggcgatgcag gggagcagtt
     8941 gtaccgccat cgtctgccca cgccgcgtga tgattaccgg cagactattg aaacgatcgc
     9001 cacgttggtt gatatggcgg agcaggcaac agggcagcgc ggaacggtag gtatgggcat
     9061 tccaggttcg atttcgccct acaccggcgt ggtgaagaat gccaattcaa cctggctcaa
     9121 cggtcagcca ttcgataaag acttaagcgc gcggttgcag cgggaagtgc ggctggcaaa
     9181 tgacgccaac tgtctggcgg tttcagaagc ggtagatggc gcggcagcgg gagcgcagac
     9241 ggtttttgcc gtgattatcg gcacgggatg cggcgcgggc gtggcattca atgggcgggc
     9301 gcatatcggc ggcaatggca cggcaggcga gtggggacac aatccgctac cgtggatgga
     9361 cgaagacgaa ctgcgttatc gcgaggaagt cccttgttat tgcggtaaac aaggttgtat
     9421 tgaaaccttt atttcaggca cgggattcgc gacggattat cgtcgtttga gcggacatgc
     9481 gctgaaaggc agtgaaatta tccgcctggt tgaagaaagc gatccggtag cggaactggc
     9541 attgcgtcgc tacgagctgc ggctggcaaa atcgctggca catgtcgtga atattctcga
     9601 tccggatgtg attgtcctgg gcggcggaat gagcaatgta gaccgtttat atcaaacggt
     9661 tccgcagttg attaaacaat ttgtcttcgg cggagaatgt gaaacgccgg tacacaaggc
     9721 gaaacatggt gattcgagcg gcgtacgcgg cgctgcatgg ttatggccac aagagtaaaa
     9781 aacccaggca attggcgtat catgcctgat gcgacgcttg ccgcgtctta tcaggcctac
     9841 aaagtgagcc gtccggtagg ccggataagg cgctcgcgcc gcatccggca acaaataacg
     9901 cgcacagtgg cggcaacccc ccggtgctcc gatgcctgat gcgacactgg cgtgtcttat
     9961 caggcctaca aaatgaacag tcccgtaggc cggataaggc gttcacgccg catccggcaa
    10021 taagcaacgt gcaccgtgac tgcaatctac cccagtggtt tcgccagcac cggactatcc
    10081 gccgcttgct ggcgcttata gcgaccatac agcagcaacg acgacatcgc agcaaacgaa
    10141 agcagggcgg cgggcagcgc cacgtaatta tatgccagcc ccagcgtcag catcatacca
    10201 ccgcaatatg cgccgacggc gctaccgagg ttaaacgcta tttgcccacc tgcggcacct
    10261 aataactctc cgcctttggc attttgcagt aataatattt gtagaggtgc tgaaagggca
    10321 aataatcccg cgcaacaaat aaaagcaaaa ataagcgacg ttgttttcat accgccgaag
    10381 aaaaagagca tcagcagtgc cagtacaatg ataaagtcag tcactgctgc aatgcgcagt
    10441 ggtgaataac gtcctgaaat cctgccactt agcatattcc ccagcaccat ccctagccca
    10501 actaacatca taataaaggt catcgccgtt tccgaaaaac cggaaataaa catcatgtat
    10561 ggctttacgt agctgaacca ggcaaacaca cctgcgttgc caaacatcgt agcagcgaaa
    10621 attaaccacg gggcagggct gcgtaaaaag tgaaattgtt cgcgtagttt tcctttcgcc
    10681 tcgtcgcgaa tatccggcac ccaaaaatag accgatgcca tcaccgcaat attaaaaata
    10741 gcgatcaaca aaaaggtgta acgccagcta aattcctgac ttaaatacgt tcccagtgga
    10801 atgcccagca aattggcgac tgtcatcccg gaaaccatcc ctgccacggc ggcggtgact
    10861 ttgccgggtt tgataatttt tgataacacg atcgcgccga cgccaaaaaa tgcaccatgc
    10921 gggaagccgg aaaccagccg accaatggcg agcatcaggt aagacgaaga gagcgtgaac
    10981 atggcgttgc caatgacgca caacgccacc agaaacaaca agatatgttt gagtgagtag
    11041 cgactggaaa aaagcgcgat gattggcgca ccgaccacca cccccagcgc ataatacgag
    11101 atcatatgcc cggcggcagg aatcgaaatt cctacgttat gcgccagctc cgtgagcacg
    11161 cccataatgc caaattcggc catccccaaa ccaaacgtgc ccagagccaa agataaaata
    11221 acttttttca taccaccatc acaaccacca gaacggctac caatcaccgt agccaataaa
    11281 gtgatagctt gcaggataac gaccagtcgg gccaagagat aattcgcccc tctgtattca
    11341 ttatcctgct gaatagttat ttcactgcaa acgcactttc cagtttgctg tagcccagtc
    11401 cattgatctt cttcactttg atctgcaccg gaatacgctc tttcatcgct tcaacgtggc
    11461 taatcacccc gatggttttg ccactggcat tcagggcatc caacgcatca agggcggtat
    11521 ccagcgtttc gctatccagc gtgccaaaac cttcatcaag gaacagcgag tcaatacgcg
    11581 ttttatggct gaccagatct gaaagcgcca gtgccagcgc cagactgacg aggaaacttt
    11641 cgccgccgga aagggtacgg gtatcgcgta ccgcatcagc ctgccaggta tcaacaacct
    11701 caacttccag cgcctcgctg gctttgcgct gtaacagata gcgcccgtgc agccgggtaa
    11761 gttgctgatt agcgagatgg actaaattat ccagcgtcag cccttgggca aatttgcgga
    11821 atttatcgcc ctctttggaa cctattagcg aattcagata tccccagtcc tcaacctgct
    11881 gcgtcatttg agcaatttgc tgcattaagg tttgttgttg ctgacggtta tctgcatcct
    11941 gcttcagctg ctggcgaatc tcgccttgac tcgtggtgtt ttcacgcaac ttttggtgag
    12001 tttgcgctaa ctcttgctga atctgctcca ccgtcacagt gagagacaac ccgccaggtc
    12061 ggtgttgctg atgctgtgtc agcgtttctg ctgtctgagt gaccagcgtt tgcgcctgac
    12121 ggcgctggtt ttccagattc tgcttgagct gttccagctg cgttagtgtt tgttcatcca
    12181 ttagcgccgc aaggaacgcc tgctgatcgt caaagacgct cgcctgtagc gcggtgtcaa
    12241 actgcgcctg ggctttttgc agactttgcg ccgccagaac atcctgttgc tgtaacgtct
    12301 gctgctggct gtgtaatgcg agacattgtt catgaacctg ccgccagttt tccagcgcca
    12361 cagtttcttc gctgtgcggg agttcatcac tttgcggcaa cgtttccaga atcggcgtca
    12421 gctgctgcat acggttttgc agcgcggtta attcgttctg gcgttgctgc cagctctgcg
    12481 cttcttgctg acgcgtcgcc aaccagctct cttcttcatc ttcctgtggc aatgtcagtg
    12541 cataacccgc caatgccgtt aagagctgct gctggcgttg ttcaatttgc tgttgatact
    12601 ggataatttg ctgattatgc gcggcaatct gcccttgtaa ttcatgccgt tggctgagta
    12661 accgcagctg gcgttcgtgc tcatcttgtg catccagcca cggttgaata tcgtcctgtg
    12721 gctgcagggt gatattgagg ctggccgtga cggcttgcca ttgttgagta agtgcttgct
    12781 catcttgtcg gaggctttgc gcttcgtttt catcgcgctg aagttgcttt gttaaggcgt
    12841 ccagttgccc acgtagcgtc gcaccttctt cgccgagctt tttcacttct ttttccagcg
    12901 ttaatagccg ggcctgatta acgcccggtt ccagcgcctg atacgcctcg accgccgggt
    12961 ggctggtgga accacaaagt gggcaaggct gacccgcctg taactgtgcg cgctgggctt
    13021 ccagcgtttt aatgcgcgct tcctgctcgc aaatggtttt cacatcggca agttgttgca
    13081 tcttttcttt ataacgatgg cgcattttgt taagtgcggc attacgttgc gtctgctcca
    13141 gagtgacgtt ctggatagcg acctgtaact gcgccagacg tttttgttgg ggaacaatct
    13201 gcccatgcag tgcgaccagg cgctgacgca gtgggcgttg ctcagcatgt tgcgcctggg
    13261 cgctagcaac ttcatcggcg gttaacgtca acgtgatcgc cgcaagcgca ttaagttttt
    13321 gctcagcatg ggttaactgt tgctgccatt gccgcagatg ctcgcgatcg ctggtttgtt
    13381 gggagaactg cgcacgccaa cccgccagtt cgttgttcca ctgacggaag cggtcgtgtt
    13441 cctgtaacca ggcattcagg ctttgttgct gctgctgtaa ttctgctgac tgcttcgccg
    13501 cgtggtggcg aatgctcgca cgaagcgcca ttgtgctctg taagcgagta tttacttctt
    13561 caatctgctg gcgagtatgc gccagcgccg tgctgtgttc tgcgatgcgt tcccagtgcg
    13621 gacgaagatt tcgtgccggt tgtgccagac tgagcgccgc cagttgaggt tgcgcttgtt
    13681 cttcttcggc taatgcctgt tgcaaggcct gttgacggcg gctggcttct tgctgcaatt
    13741 cgtccagacg cgttaaccag tttagcgatt gttgttcttg ctgctgcgcg gtaattaact
    13801 gtttttcttc gtcagtaagt acctgcaaac tcgctgtcag cgattgcact tgttccggcg
    13861 tgagcaacgc gacgccgctg gcctgcgctt gcagcttctc cagctctgtg cgggccgatt
    13921 tgtgctgctc aaaaaccatc gccgagattt gcccgtagat ttcagtgccg gttaactcct
    13981 cgagcaattc tgcgcgttct ttgggtttgg cattcaggaa ggcagcaaat tgcccctgcg
    14041 aaagcagcat cgaacgggtg aagcgcccgt aatccagtcc ggttaacgtc gccgtcagtt
    14101 ccagcttatc tttcactttg tcggcgagaa ttttgccgtc tgcacagcgc gccagctcta
    14161 cgcgtggcac ctgcaaatta ccgtccggct ggttacgcgc ccgattctgg ctccagaacg
    14221 cgcgatacgc ttcatctttg acttcaaact ccacttccgc cagacattcg gcggtatcgc
    14281 gggtcatgag atcattttgc gattgtgaaa cgttagagag gcgcggagtt tcgtgataca
    14341 gcgccagaca aatggcgtcc agcagggtgg ttttccccgc accggttggg ccggtaatag
    14401 caaacagccc gttgctggcg aacggctcgc gggtgaaatc aatcttccat tcgcctttta
    14461 atgagttcag gtttttcagg cgcaggctga gaattttcat gcttcgtgtt ctccggcgag
    14521 gctatgcaac gtcgtggcga aaagatgctg cagacgttgc tgctgtgatt catccagttc
    14581 ttccagtgcc agacggcgat tgaacacctc ttcgacgctg agttcgctga gggtttcacg
    14641 ctgttggctg gctaacacac gctcgcgctg ttcacgactc cggcgtacca gcaatacttc
    14701 gacaggcaat gattcggtta atgcctggat tttgcgctga atatcatgca gatactcatc
    14761 agtagtgatt tcgatatcca gccagacagg cggctcctgt gatacatcgc gccactgttc
    14821 cagctgtgcg gtaatcgacg ccagatcgcc tttcagcacc gccatgggtt gcgttaccgg
    14881 tacgttcagg ttttccacgc tctctaattt gccgtttgaa aatgtcacca gatggacata
    14941 tttactctta ccgcattcat caaaactcag tggaatgggg gagccgcaat agcgaacatg
    15001 ttccatgccg ccaataagct gcgcgcggtg aatatgcccg agcgcgatgt agtcggctgg
    15061 tggaaagttt tgtgccggaa acgcgtccag cgtgccaata taaatgtcac gcacggcgtc
    15121 acttttactg gcacccacgg tcgttaaatg tccagtggcg atgatgggca gaggctgatc
    15181 gccgcgcagt ttgcaggcat cggcataatg ttgttgataa taatcagtaa tagccgccag
    15241 caaatgctgc tgtttttcaa taccgttaag ccccgcctgg ctggtaataa tgtcacgcgg
    15301 gcgtaaaaaa ggtatgggac acagcactgc gcctggcgtc ccgtcgcgac ggggcaatat
    15361 ttgcggcgca tgtccggcgc tggcgaccac ggtagtattg aggaacgcca tgatatcgcg
    15421 cgattcattc agcgtggcga ccgagtcatg gtttcctgcc agtaccacca gatgacagcc
    15481 agtttgctgt aaattgacaa caaaacggtt gtataacgtg cgggcgtaac tgggcggcga
    15541 gccggtatcg aaaacatcac cggcaacaat aatcgcatcc accagatggg cttgtgctgt
    15601 ctccagcagc cagtcaagaa aagcctgatg ttcagcttcg cggcttttac tgtagaagtt
    15661 ctggccgaga tgccagtctg aggtgtgaag gatgcgcata acggttccct ggcgaaaaag
    15721 catgggcgcg attataccca aacagatgtg ccatttgctt ttttctgtgc cacggaaatc
    15781 aataacctga agatatgtgc gacgagcttt tcataaatct gtcataaatc tgacgcataa
    15841 tgacgtcgca ttaatgatcg caacctattt attacaacag ggcaaatcat ggcgagacgt
    15901 attctggtcg tagaagatga agctccaatt cgcgaaatgg tctgcttcgt gctcgaacaa
    15961 aatggctttc agccggtcga agcggaagat tatgacagtg ctgtgaatca actgaatgaa
    16021 ccctggccgg atttaattct ccttgactgg atgttacctg gcggctccgg tatccagttc
    16081 atcaaacacc tcaagcgcga gtcgatgacc cgggatattc cagtggtgat gttgaccgcc
    16141 agaggggaag aagaagatcg cgtgcgcggc cttgaaaccg gtgcggatga ctatatcacc
    16201 aagccgtttt ctccgaagga gctggtggcg cgaattaaag cggtaatgcg ccgtatatcg
    16261 ccgatggcgg tggaagaggt gattgagatg caggggctaa gtctcgatcc gacatctcac
    16321 cgggtgatgg cgggcgaaga accgctggag atggggccaa ctgaatttaa actgctgcac
    16381 ttttttatga cgcatcccga gcgcgtgtac agtcgcgagc aactgttaaa tcacgtatgg
    16441 ggaaccaacg tgtatgtgga agatcgtacg gtcgatgtcc acattcgtcg cctgcgtaaa
    16501 gcactggagc ccggcgggca tgaccgcatg gtgcagaccg tgcgcggtac agggtatcgt
    16561 ttttcaaccc gcttttaagg ccttgctcat cggacgtaga gcagggctta tgatttctta
    16621 actggagtat cttacgtgct ggaacggctg tcgtggaaaa ggctggtgct ggagctgcta
    16681 ttttgctgcc tcccggcttt catcctgggt gcatttttgg gttacctgcc ctggtttttg
    16741 ctggcatcgg taacaggact gcttatctgg catttctgga atttattgcg cctttcatgg
    16801 tggctgtggg tggatcgtag tatgaccccg ccaccggggc gtggtagctg ggaaccgcta
    16861 ctatacggct tacaccagat gcagctgcga aataaaaaac gccgccgtga actgggcaat
    16921 ctgattaaac gctttcgtag cggcgcggag tcgctgcccg acgcggtggt gctgaccacg
    16981 gaagagggcg gtattttctg gtgcaacggt ctggcgcaac agattcttgg cttgcgctgg
    17041 ccggaagata acgggcagaa catccttaac ttgctgcgtt acccggagtt tacgcaatat
    17101 ctgaaaacgc gtgatttctc tcgcccgctc aatctggtgc tcaataccgg gcggcatctg
    17161 gagattcgcg tcatgcctta tacccacaaa cagttgctga tggtggcgcg agatgtcacg
    17221 caaatgcatc aactggaagg ggcgcggcgt aacttttttg ccaacgtgag ccatgagtta
    17281 cgtacgccat tgaccgtgtt acagggttac ctggagatga tggatgagca accgctggaa
    17341 ggcgcggtac gtgaaaaagc gttgcacacc atgcgtgagc agacccagcg gatggaaggg
    17401 ttggtgaagc aattgctgac gctgtcgaaa atagaagccg caccgacgca tttgctcaat
    17461 gaaaaggttg atgtgccgat gatgctgcgc gtcgttgagc gcgaggctca gactctgagt
    17521 cagaaaaaac agacatttac ctttgagata gataacggcc tcaaggtgtc aggcaacgaa
    17581 gatcagctac gtagtgcgat ttcgaacctg gtctataacg ccgtgaatca tacgccggaa
    17641 ggcacgcata tcaccgtacg ctggcagcga gtgccgcacg gtgccgaatt tagtgttgaa
    17701 gataacggac cgggcattgc accggagcat attccgcgcc tgaccgagcg tttttatcgc
    17761 gttgataaag cgcgttcccg gcaaaccggt ggtagcggat tagggttagc gatcgtgaaa
    17821 catgcggtga atcatcacga aagtcgcctg aatattgaga gtacagtagg aaaaggtaca
    17881 cgtttcagtt ttattatccc ggaacgttta attgccaaaa acagcgatta attcgccttt
    17941 gtcatctttt attgccataa gccagccgat gctggcttat tttctttgca gtcgaaatac
    18001 gggcgttaga ttttacaatg gttggtgatt ttttgttcgc atgattagcc atgtcttttt
    18061 cattgaaata gtgttttata ctggttggtg atttcttatc gctatatacc tctggttttt
    18121 agatcccttc ttgctttaaa acgttataag cgtttaaatt gcgcttcagg tgctgtcata
    18181 ctgactgcat ttacgcggta aatcgaaaaa ctattcttcg ccgcgcctgg ttgggagtat
    18241 ttcccgctaa aattgtttaa atataccgct gtatcatccc cagggattgg cacaaaaatt
    18301 taacgttaca acaccacatc cacaggcagt atgatttatg acccatcaat taagatcgcg
    18361 cgatatcatc gctctgggct ttatgacatt tgcgttgttc gtcggcgcag gtaacattat
    18421 tttccctcca atggtcggct tgcaggcagg cgaacacgtc tggactgcgg cattcggctt
    18481 cctcattact gccgttggcc taccggtatt aacggtagtg gcgctggcaa aagttggcgg
    18541 cggtgttgac agtctcagca cgccaattgg taaagtcgct ggcgtactgc tggcaacagt
    18601 ttgttacctg gcggtggggc cgcttttcgc tacgccgcgt acagctaccg tttcttttga
    18661 agtgggcatt gcgccgctga cgggtgattc cgcgctgccg ctgtttattt acagcctggt
    18721 ctatttcgct atcgttattc tggtttcgct ctatccgggc aagctgctgg ataccgtggg
    18781 caacttcctt gcgccgctga aaattatcgc gctggtcatc ctgtctgttg ccgcaattat
    18841 ctggccggcg ggttctatca gcacggcgac tgaggcttat caaaacgctg cgttttctaa
    18901 cggcttcgtc aacggctatc tgaccatgga tacgctgggc gcaatggtgt ttggtatcgt
    18961 tattgttaac gcggcgcgtt ctcgtggcgt taccgaagcg cgtctgctga cccgttatac
    19021 cgtctgggct ggcctgatgg cgggtgttgg tctgactctg ctgtacctgg cgctgttccg
    19081 tctgggttca gacagcgcgt cgctggtcga tcagtctgca aacggtgcgg cgatcctgca
    19141 tgcttacgtt cagcatacct ttggcggcgg cggtagcttc ctgctggcgg cgttaatctt
    19201 catcgcctgc ctggtcacgg cggttggcct gacctgtgct tgtgcagaat tcttcgccca
    19261 gtacgtaccg ctctcttatc gtacgctggt gtttatcctc ggcggcttct cgatggtggt
    19321 gtctaacctc ggcttgagcc agctgattca gatctctgta ccggtgctga ccgccattta
    19381 tccgccgtgt atcgcactgg ttgtattaag ttttacacgc tcatggtggc ataattcgtc
    19441 ccgcgtgatt gctccgccga tgtttatcag cctgcttttt ggtattctcg acgggatcaa
    19501 ggcatctgca ttcagcgata tcttaccgtc ctgggcgcag cgtttaccgc tggccgaaca
    19561 aggtctggcg tggttaatgc caacagtggt gatggtggtt ctggccatta tctgggatcg
    19621 cgcggcaggt cgtcaggtga cctccagcgc tcactaaatc actgaacatt tgttttaacc
    19681 acggggctgc gatgccccgt ggttttttat tgtgttgatg ggttaggaat tgatggaaag
    19741 taagaacaag ctaaagcgtg ggctaagtac ccgacacata cgctttatgg cactgggttc
    19801 agcaattggc accgggctgt tttacggttc ggcagatgcc atcaaaatgg ccggtccaag
    19861 cgtgttgttg gcctatatta tcggtggtat cgcggcgtat atcattatgc gtgcgctggg
    19921 ggaaatgtcg gtacataacc cggcagccag ctctttctcg cgttatgcgc aggaaaacct
    19981 cggcccgctg gcaggttaca ttaccggctg gacctactgc tttgaaatcc ttattgtcgc
    20041 catcgccgat gtgaccgctt ttggtatcta tatgggtgtc tggttcccga cggtgccgca
    20101 ctggatttgg gtactgagtg tggtgctgat catttgcgcc gtaaacctga tgagcgtgaa
    20161 ggtattcggt gagctggagt tctggttctc gttctttaaa gtcgccacta tcatcatcat
    20221 gattgtcgcc ggtttcggca tcatcatctg ggggattggc aacggcgggc aaccgaccgg
    20281 tattcataac ctgtggagca acggcggctt cttcagtaac ggctggcttg gtatggtgat
    20341 gtcgttgcaa atggtgatgt ttgcttacgg tgggatcgaa attatcggga ttaccgccgg
    20401 tgaagcgaaa gatcctgaga aatcgattcc gcgtgcgatt aactccgtgc cgatgcgtat
    20461 tctggtgttc tacgtcggta cgctgttcgt cattatgtct atctacccgt ggaatcaggt
    20521 tggcactgcc ggtagcccgt ttgtgctgac gttccagcat atgggcatta cctttgccgc
    20581 cagcattctt aactttgttg tgctgaccgc ttcgctgtcg gcaattaaca gtgacgtatt
    20641 tggtgtaggc cgtatgctcc acggtatggc agagcagggc agcgcgccaa aaattttcag
    20701 caaaacctcg cgtcgcggta ttccgtgggt tacggtgctg gtgatgacta ccgcgctgct
    20761 gtttgcggtg tatctgaact acatcatgcc ggaaaacgtc ttcctggtga tcgcttcgct
    20821 ggcaaccttc gccacggtgt gggtgtggat tatgatcctg ctgtcgcaaa tcgccttccg
    20881 tcgccgtttg ccgccagaag aagttaaggc gctgaaattt aaagtgccgg gtggggtagc
    20941 aacgaccatc ggcggtttga ttttcctgct ctttattatc gggttgattg gttatcaccc
    21001 tgatacgcgt atctcgctgt atgttggttt cgcgtggatt gttgtgctgt tgattggctg
    21061 gatgtttaag cgccgccacg atcgtcagct ggctgaaaac cagtaatcct tgcgttctgt
    21121 aagccggttc aggaggaaat cctgatccgg ctattccgaa agttatccgc ccccgtcctc
    21181 ctcccccaaa tatccttcag atgatgagtg atcctgcatt aggctatggc aaggtgatca
    21241 gattttcatc acaggggaat tatgatgtta aatgcatggc atctgccggt gcccccattt
    21301 gttaaacaaa gcaaagatca actgctcatt acactgtggc tgacgggcga agacccaccg
    21361 cagcgcatta tgctgcgtac agaacacgat aacgaagaaa tgtcagtacc gatgcataag
    21421 cagcgcagtc agccgcagcc tggcgtcacc gcatggcggg cggcgatcga gctctcctgc
    21481 ggacaacctc ggcggcgtta tagtttcaaa ttgctgtggc acgatcgcca gcgttggttt
    21541 acaccgcaag gcttcagccg aatgccgccg gcacgacagg agcagtttgc catcgatgta
    21601 ccggatatcg gcccacaatg ggctgcggat cagatttttt atcagatctt ccctgatcgt
    21661 ttcgcccgta atcttcctcg tgaagctgaa caggatcatg tctattacca tcacgcagcc
    21721 ggacaagaga tcatattgcg tgactgggat gaaccggtca cggcgcaggc tggcggatca
    21781 acgttctatg gcggcgatct ggacgggata agtgaaaaac tgccgtatct gaaaaaactt
    21841 ggcgtgacgg cgctgtatct caatccggtg tttaaagctc ccagcgtgca taaatacgat
    21901 accgaggatt atcgccatgt cgatccgcag tttggcggtg atggggcgtt gctgcgtttg
    21961 cgacacaata cgcagcagct gggaatacga ctggtgctgg acggcgtgtt taaccacagt
    22021 ggcgattccc atgcctggtt tgacaggcac aatcgtggca cggggggagc ttgtcacaac
    22081 cccgaatcac cctggcgtga ctggtactcg tttagtgatg atggcacggc gctcgactgg
    22141 ctgggctatg ccagcttgcc gaagctggat tatcagtcgg aaagtctggt gaatgaaatt
    22201 tatcgcgggg aagacagtat tgtccgccac tggctgaaag cgccgtggaa tatggatggc
    22261 tggcggctgg atgtggtgca tatgctgggg gaagcgggtg gggcgcgcaa taatttgcag
    22321 cacgttgccg ggatcaccga agcggcgaaa gaaacccagc cggatgcgta tattgtcggc
    22381 gaacattttg gcgatgcacg gcaatggtta caggccgatg tggaagatgc cgccatgaac
    22441 tatcgcggct tcacattccc gttgtgggga tttcttgcca acaccgatat ctcttacgat
    22501 ccgcagcaaa ttgacgccca aacctgtatg gcctggatgg ataattaccg cgcagggctt
    22561 tctcatcaac aacaattacg tatgtttaat cagctcgaca gccacgatac tgcgcgattt
    22621 aaaacgctgc tcggtcggga tgttgcgcgc ctgcccctgg cggtggtctg gctgttcacc
    22681 tggcctggtg taccgtgcat ttattacggt gatgaagtgg gactggatgg caaaaacgat
    22741 ccgttttgcc gtaagccgtt cccctggcag gtggaaaagc aggattcggc gttattcgcg
    22801 ctgtaccagc gaatgattgc gctgcgtaag aaaagtcagg cgttgcgtcg tggcggctgt
    22861 caggtgctgt atgcggaaga taacgtggtg gtatttgtcc gcgtgctgaa tcagcagcgt
    22921 gtactggtgg caatcaaccg tggcgaagcc tgtgaagtgg tgctacccgc gtcgccgttg
    22981 cttaatgtcg cgcaatggca acgcaaagaa ggtcacgggc aactgacgga cgggattctg
    23041 gctttgcctg ccatttcggc tacggtgtgg atgaattaac gtcttataac gccttgcgtg
    23101 acgcctgctc catcatccgc ggataaaact gccagaagcg ggtttcgaga gcatcgtaat
    23161 gggcgtctaa atcgtaccag gagtcacgca gggcatccag acgtgggcga cggcttgcca
    23221 tgccgtttaa cacgctctgg atgaaatcca tatcgcgata gcgcaccaac cactgctctg
    23281 accataagta gttgttcaga ttgataaagc gtggcggtga gtctggaaga atagtcatca
    23341 cttgctcccg ggcataacag gtaaattcct gtagcggaaa atcgggcgac agctgcgacc
    23401 agtggcggga cagaaagtga tcccacatca catccagcgt aataggcgcg acacggcgcg
    23461 tttcattacg aaaccactcc cgcgcttcgc ggacttctgg cagattgtcg gttaatacgt
    23521 cgattcgccg atgcatatga atgccagcca cgacgtcggg cggaaaactt tcttcaggat
    23581 ttccgcgtac gaaatcagcc agtaaattgc cggaaagcga gctttccgcg agatgggcta
    23641 aatgcaggtg agctaaaaaa ttcatcgatt atattctatc caaagggggg taaaggttgc
    23701 agggagagcg ccccggcact agactacccg cctcttattt tagtctgagt cagtgtcatg
    23761 cgcgttaccg atttctcttt tgaattgccc gaatccctga ttgcccacta tcccatgcct
    23821 gaacgcagta gctgtcgttt actgtcgctg gacgggccga cgggcgcgct gacgcacggt
    23881 actttcaccg atttactcga taagctcaac cccggcgatc ttctggtttt taataatacc
    23941 cgcgtgatcc cggcgcgtct gtttgggcgt aaagccagcg gcggcaagat tgaagtgctg
    24001 gttgagcgga tgctcgacga caaacgcatt cttgcgcata ttcgcgcctc gaaagcgcca
    24061 aaacctggcg cagaactgct gctgggcgat gacgaaagta ttaacgcaac aatgaccgcg
    24121 cgccacggcg cactgtttga agtcgaattt aatgatcaac gttcggtgct ggatattctc
    24181 aacagcatcg gccatatgcc gctgccgccg tacatcgacc gtccggacga agatgcagac
    24241 cgcgaacttt atcaaacggt ttatagcgaa aaacccggcg cggtagcagc accgaccgcc
    24301 ggactgcact ttgacgaacc tttgctggaa aaattacgcg ccaaaggcgt ggagatggcg
    24361 tttgtgacgt tgcacgttgg tgcgggcacc ttccagccgg tgcgcgtcga caccattgaa
    24421 gatcacatca tgcactcgga atacgctgaa gtgccgcagg atgtggtaga cgcggtactg
    24481 gcggcgaaag cgcgcggtaa ccgggtgatt gcggttggca ccacctcagt acgttcgctg
    24541 gaaagtgcgg ctcaggcagc gaaaaacgat ctcattgaac cgttctttga cgatacccaa
    24601 atctttatct atccgggctt ccagtacaaa gtggtcgatg cgctggtgac gaacttccac
    24661 cttccggaat cgacgctgat tatgctggtt tcggcatttg ctggttatca acacaccatg
    24721 aatgcctata aagcggcggt agaagagaaa tatcgctttt ttagttacgg tgatgcgatg
    24781 tttatcacgt acaatccgca ggcaattaat gagcgcgttg gggagtaatt ccgcggcgct
    24841 ggtttaaacg ttggactgtt tttctgacgt agtggagaaa aaatgaaatt tgaactggac
    24901 accaccgacg gtcgcgcacg ccgtggccgc ctggtctttg atcgtggcgt agtggaaacg
    24961 ccttgtttta tgcctgttgg cacttacggc accgtaaaag ggatgacgcc ggaagaagtt
    25021 gaagccactg gcgcgcaaat tatcctcggc aacaccttcc acctgtggct gcgcccgggc
    25081 caggaaatca tgaaactgca cggcgatctg cacgatttta tgcagtggaa aggaccaatc
    25141 cttaccgact ccggcggctt ccaggttttc agccttggtg atattcgtaa aatcaccgaa
    25201 cagggtgttc acttccgtaa cccgatcaac ggcgacccga ttttcctcga cccggaaaag
    25261 tcgatggaga ttcagtacga tcttggttcg gatatcgtca tgatctttga tgagtgtacg
    25321 ccgtatcctg ctgactggga ttatgcaaaa cgctccatgg agatgtctct gcgttgggcg
    25381 aagcgtagcc gtgagcgttt tgacagtctc ggaaacaaaa atgcgctgtt tggtatcatt
    25441 cagggcagtg tttacgaaga tttacgtgat atttctgtta aaggtctggt agatatcggt
    25501 tttgatggct acgctgtcgg cggtctggct gtgggtgagc cgaaagcaga tatgcaccgc
    25561 attctggagc atgtatgccc gcaaattccg gcagacaaac cgcgttacct gatgggcgtt
    25621 ggtaaaccag aagacctggt tgagggcgta cgtcgcggta tcgatatgtt tgactgcgta
    25681 atgccaaccc gcaacgcccg aaatggtcat ttgttcgtga ccgatggcgt ggtgaaaatc
    25741 cgcaatgcga agtataagag cgatactggc ccactcgatc ctgagtgtga ttgctacacc
    25801 tgtcgcaatt attcacgcgc ttacttgcat catctcgacc gttgcaacga aatattaggc
    25861 gcgcgactca acaccattca taaccttcgt tactaccagc gtttgatggc gggtttacgc
    25921 aaggctattg aagagggtaa attagagagc ttcgtaactg atttttacca gcgtcagggg
    25981 cgagaagtac cacctttgaa cgttgattaa tattaataat gagggaaatt taatgagctt
    26041 ttttatttct gatgcggtag cggcaacggg tgcaccggcg caaggtagcc cgatgtcttt
    26101 gattttgatg ctggtggtat tcggtctgat tttctatttc atgatcctgc gtccacagca
    26161 gaagcgcacc aaagaacaca aaaagctgat ggactccatc gctaaaggtg atgaagtgct
    26221 gacgaacggt ggcctggtcg gtcgcgtaac caaagtagcg gaaaacggct acattgctat
    26281 cgcactgaat gacaccactg aagtagttat taaacgtgac ttcgtagctg ccgttctgcc
    26341 gaaaggcacc atgaaggcgc tgtaattaaa atttttccct aagggaattg ccgtgttaaa
    26401 ccgttatcct ttgtggaagt acgtcatgct gatcgtggtg attgtcatcg gtctgctgta
    26461 tgcgcttccc aacctgtttg gtgaggatcc ggctgttcag atcactggtg cgcgcggagt
    26521 cgccgccagt gagcaaacgc tgatccaggt ccagaaaacg ttacaagaag aaaaaataac
    26581 tgctaagtct gtggcactgg aagagggcgc tattcttgcg cgcttcgact ccactgacac
    26641 ccagctgcgc gctcgtgaag cattaatggg cgttatgggt gacaaatacg tcgtggcgct
    26701 taatcttgcc ccggcaacgc cgcgctggct ggcagctatt catgctgagc cgatgaagct
    26761 cggccttgac ctgcgtggcg gcgttcactt cctgatggaa gtggatatgg acaccgcgct
    26821 tggcaaactc caggaacaaa atatcgatag cctgcgcagc gacctgcgtg aaaagggcat
    26881 cccgtatacc accgttcgta aagaaaacaa ctacggcctg agcatcactt tccgcgatgc
    26941 taaagctcgt gatgaagcca ttgcgtatct gagcaagcgc catccggacc tggtgattag
    27001 cagccagggc agcaaccagc tgcgtgcggt aatgagcgat gctcgtctga gtgaagcgcg
    27061 tgaatatgcg gtgcagcaga acatcaatat cctgcgtaac cgtgtaaacc aacttggcgt
    27121 ggcggagccg gtggttcagc gtcagggtgc tgaccgtatc gttgttgaac tgccaggtat
    27181 tcaggacact gcgcgtgcga aagagattct gggtgcgacg gcaacgctgg aattccgtct
    27241 ggtaaacacc aacgttgatc aggccgctgc ggcatccggt cgcgtaccgg gcgactctga
    27301 agtgaaacag acccgcgaag gtcagccggt tgtgctgtac aaacgcgtaa ttctgaccgg
    27361 tgaccatatc accgactcca cttccagcca ggacgaatac aaccagccgc aggttaacat
    27421 ctctctcgat agcgcgggtg gtaacatcat gtctaacttc accaaggaca acatcggcaa
    27481 accgatggca accctgtttg tggagtacaa agacagcggt aagaaagatg caaacggtcg
    27541 tgcggttctg gtgaaacagg aagaggtgat taatatcgcc aacatccagt ctcgtctggg
    27601 taacagcttc cgtattactg gcatcaataa cccaagcgaa gcgcgtcagc tttcactgct
    27661 gctgcgtgcc ggtgcgttga tcgcgccgat tcagattgtt gaagaacgta ccattggccc
    27721 aaccctgggt atgcagaaca ttgagcaggg gctggaggct tgccttgccg gtctgctggt
    27781 ttctattctg ttcatgatca tcttctataa gaagtttggt ctgattgcga ccagtgctct
    27841 gattgccaac ttgatcttga ttgtcggtat tatgtcgctg ttgccaggcg caacgctgag
    27901 tatgccaggt atcgcgggta tcgtcttaac ccttgcggta gcggtcgatg cgaacgtact
    27961 gatcaacgaa cgtattaaag aagagttgag caacggacgt actgttcaac aggcaattga
    28021 tgaaggttat cgtggcgcat tcagttccat cttcgatgcg aacatcacca cgctgattaa
    28081 agtcatcatc ctgtacgcag tgggtaccgg ggcaattaaa gggttcgcga ttactaccgg
    28141 tatcggtgtg gcgacgtcga tgtttaccgc gattgtcggt acgcgtgcca tcgtaaacct
    28201 gctatatggc ggcaagcgcg tcaagaagct gtcaatctga ggagtgcgat gtggcacagg
    28261 aatatactgt tgaacaacta aaccacggcc gtaaagtcta tgactttatg cgctgggact
    28321 actgggcttt cggcatctct ggtctgctgt taatcgccgc tatcgttatt atgggcgtgc
    28381 gcggctttaa ctgggggctg gatttcaccg gtggtacggt tattgaaatt acgctcgaaa
    28441 aaccggctga aattgacgta atgcgtgatg cattgcaaaa agccggtttt gaagagccga
    28501 tgctgcaaaa ctttggtagc agccacgaca tcatggtccg tatgccgcct gctgaaggcg
    28561 aaaccggtgg tcaggtgctg ggcagccagg ttctgaaggt gattaacgaa tccaccaatc
    28621 agaatgcggc agtgaagcgt attgagttcg tcggtccgag cgtgggggca gaccttgcgc
    28681 aaaccggtgc gatggcgttg atggcggcgc tgctgtctat cctcgtgtac gttggtttcc
    28741 gctttgagtg gcgactggcg gcaggggttg ttattgcgct ggcgcacgac gttatcatta
    28801 cgctgggtat tttgtcgtta ttccatatcg agattgacct gaccattgtg gcatcgttga
    28861 tgtcggttat cggttactcg cttaacgaca gtatcgtggt atcggaccgt attcgtgaaa
    28921 acttccgcaa gatccgtcgc ggtacgcctt acgaaatctt taacgtgtcc ttgacccaga
    28981 cgctgcaccg taccttgatc acatccggta ctaccttgat ggttatcctg atgctgtacc
    29041 tcttcggtgg tccggtactg gaaggcttct cgctgaccat gcttatcggt gtttccatcg
    29101 gtactgcatc ttccatctat gtggcatctg cgctggctct gaaactgggt atgaagcgcg
    29161 aacacatgtt gcagcagaaa gtggaaaaag aaggggcgga tcagccgtca attctgcctt
    29221 aatcaagttt cagctgatgt tgaaaatccc ggtcagaaga tcgggatttt ttttgatgta
    29281 aggtgattgc gaaaatcccc gcatcttggg aaactgcgcg taaccctaca tttcatccag
    29341 gtaacttttt catggctatc atcccaaaaa actatgcgcg gttagaaagc ggctatcgcg
    29401 aaaaagcatt aaaaatctat ccgtgggtct gcggtcgctg ttcccgcgag tttgtttatt
    29461 ccaacctgcg tgaacttacc gttcaccaca ttgatcacga ccatactaat aacccggaag
    29521 atggcagtaa ctgggaatta ctttgtctct attgccacga tcatgagcat tcgaaataca
    29581 ccgaagcgga tcagtatggt acgaccgtta tcgcagggga agatgcgcag aaagatgtcg
    29641 gtgaagcgaa gtacaaccca ttcgctgatt tgaaagcgat gatgaacaag aagaagtgat
    29701 aaaaaatgcc ggatatgaaa tccggcattc tcacaattag aagttgtaac ctactaccag
    29761 ataaccaccc cagccggtag agcgaacgtt gaagttgccg ttgccgaagt tcagttctgc
    29821 atcgtcattc cactgaccac cgttatgcca gtaacgggca acgacagagt agtgccagtg
    29881 atcgtaattc agcgccagaa tatggctgga cgcaatagag ttattggtac gtgttttaat
    29941 accgttgttc gcataaccgc tgtcatcgcc caggtcggaa ccccagtcga agttggtgaa
    30001 gccgatgtag ctcagctggc cgccccacag atcggtaatc ggcacaaagt acttcacttt
    30061 gaaacggtaa ccgtcccact cgttttcgtt cgctgcgccg tagttctgcc actggtattt
    30121 cgcatagacg ttcatggaca ggctcatcgg cagaccagta tcgatgtcgg tacccagacc
    30181 catgtaccag gtgctctggc ggccatcttt attacgaccc atgtcgtaaa tgtagttgtt
    30241 cgcgaagtac cactctttga acggaccgaa gctaaggtca gtattggtca gcttgtcaat
    30301 ggagaaacgc ggttcgattt ccataaacag cggagaaccg tggttccaga taccttttgc
    30361 atcggagtta ccgccgaaga ataccggcgc atccgcataa ccatagaagt cgaaccagtc
    30421 ttttttagcg aatgcttcgt actcaaggta ggtatcgttg cggagctgcg gtccgaaacg
    30481 ggtgtgatag cttccgacaa cgttaacgct ctggtgccac cagtcggaaa gatactgcgg
    30541 tttgtcgttt tcagctgcgt tgacagtaaa agacgaagag agcgccagta ccgcaccggc
    30601 tgccagtaat gtttttttca tatgtatgcc actgtttgaa aatcccttgc gggagtgaaa
    30661 aaggcgcaaa ttgcgtttct aaatatttcg tatacagagg agcctattat aaaaatcatt
    30721 gctcacaaaa atatgtttcg tttcacagtt ctatcattta cgtaatcgat tgcgttcacg
    30781 tttacacaca ttcgggcggg gattgtactg actttcaccc ttgttgcaaa cttttactat
    30841 caatccaggt gatgtaagcg gagtaacaaa atgacggaga aagatgttgc gggacgcaca
    30901 atatcgcccc gcaatacgtt tactgcataa caggttgaat gtcgtggata cgtacaaagc
    30961 ctaactgatc cacagaaata ccctttaact gtaacggaat atcaacatcg ctgggggcga
    31021 ggacgctggc aggggcgtta atcaattgat tctgcacatt gatttcctga aagttgtcta
    31081 ttgttccctg aatttgccca tattcaacgg ttccgctgaa tgcgggtaaa gggtcattgg
    31141 attcgccctg aatacgtagc gtcagggtag tgccatctgt gtcaggcgta atattcacca
    31201 gcgacatacg taaagtaccg atctggcttt ccagtcttgc tggtgttttt gctccaggca
    31261 gaaggtaaac cccactgctg gattttgcat tcagcttgtt ttgctgagtg attttgaccg
    31321 tttctttatt gagttgcgtc atctcctggt tcagcgtgct gacgctgtgt ttcatctgtc
    31381 gcacttcact ttgctgcaca caggcgctaa ggctgaacag gcttcccagc aggagcagtc
    31441 gaaaaacgtt agtattcata ggtcgtccct ttctcgtcgc aattagccta atggtagagg
    31501 gtaaaagcag tgaaagcatc gatcctttat ctcaaaagcg ttgcgccttt gttgtatcgt
    31561 cagttcaggg taaaatagat ttctgttaac cacctggtca ggacgccgta tgcattgccc
    31621 attctgtttc gccgtggaca ctaaggtaat tgactctcgt ctcgtgggcg agggttcatc
    31681 cgtacgccgc cgtcggcagt gtctggtgtg taatgaacgt ttcaccacct ttgaagtggc
    31741 ggagctggtt atgccgcgtg ttgtaaaaag caacgacgtg cgtgaaccgt ttaatgaaga
    31801 gaaattacgt agcggaatgc tgcgggcgct ggaaaaacgt ccggtgagtt ccgatgacgt
    31861 cgaaatggca atcaatcata taaaatcgca gctgcgcgcc accggtgagc gcgaagtgcc
    31921 gagcaagatg attggcaatc tggtgatgga gcaattgaaa aagctcgata aagtcgccta
    31981 tatccgtttt gcctctgtct accgcagttt cgaagatatc aaagaatttg gcgaagagat
    32041 cgcgcgcctg gaggactaag ccgtgcagga cgagtattac atggcgcggg cgctaaagct
    32101 ggcgcaacga ggacgtttta ccacgcatcc caacccgaat gtcgggtgcg tcattgtcaa
    32161 agatggcgaa attgtcggtg aaggttacca tcaacgagcg ggtgaaccgc atgccgaggt
    32221 acacgcgttg cgcatggccg gcgaaaaagc caaaggcgca acggcgtatg tcacactcga
    32281 accctgtagc catcatggtc gtacgccacc gtgttgtgat gcattaattg ctgcgggcgt
    32341 ggcgcgcgtg gttgctgcaa tgcaagaccc caatccgcag gttgctggac gtggacttta
    32401 ccgtctgcaa caggctggca ttgacgtcag ccacgggctg atgatgagtg aagctgagca
    32461 attgaataaa ggctttctca agcggatgcg caccggcttt ccttatattc agttaaaact
    32521 tggcgcatcg cttgatggtc gcacggcgat ggcgagtggc gaaagccagt ggatcacttc
    32581 gcctcaggcg cgacgcgacg tacaacgact gcgcgcgcaa agtcatgcca ttttaaccag
    32641 cagcgccacg gtgctggcgg atgatccagc cttaacagtg cgttggtctg aactggatga
    32701 acaaactcag gggctctacc cgcaacaaaa tctccgtcag ccagtacgta ttgtgattga
    32761 tagccaaaat cgcgtgacgc cggaacatcg cattgtgcag cagcccggcg aaacctggtt
    32821 cgcgcgtacg caggaagatt ctcgtgagtg gccggaaacg gtgcgtacct tgctgattcc
    32881 agagcataaa ggtcacctgg atctggttgt actaatgatg caactgggta aacagcagat
    32941 taacagcatc tgggtggaag cggggccaac gctcgctggc gcattgctac aggcgggttt
    33001 agtcgatgag ctgattgtct atatcgcacc taaactatta ggcaacgacg cccgtggatt
    33061 atgcacgctg ccagggcttg agaaattagc cgacgctccc caatttaaat tcaaagagat
    33121 acgtcatgta ggcccggatg tttgcctgca tttagtgggt gcatgatctc ccggctcgaa
    33181 agggaagcag cgcacgaaat attatgctaa aatccgcccc cctgcggggc catactcgaa
    33241 cccgaaggaa gaaaatgaac attattgaag ctaacgttgc taccccggac gctcgcgtcg
    33301 ccatcaccat cgcgcgtttc aacaacttta tcaatgacag cctgctggaa ggtgcaattg
    33361 acgcactgaa acgtatcggt caggtaaaag atgaaaacat taccgttgtt tgggtgcctg
    33421 gtgcctatga gctgccgctg gcggcgggtg cactggctaa aaccggtaaa tacgacgcgg
    33481 tgattgcgct gggtacggtt attcgtggtg gcactgccca ctttgaatat gtcgctggtg
    33541 gtgcaagcaa cggcctggcg catgttgccc aggacagcga aattccggtt gcttttggtg
    33601 ttctgaccac tgaaagcatt gaacaagcga tcgaacgtgc tggcaccaaa gctggcaaca
    33661 aaggtgcaga agctgcactg accgcgcttg aaatgattaa tgtattgaaa gccatcaagg
    33721 cctgaaatta gtaaggggaa atccgtgaaa cctgctgctc gtcgccgcgc tcgtgagtgt
    33781 gccgtccagg cgctctactc ctggcagttg tcccagaacg acatcgctga tgttgaatac
    33841 cagttcctgg ctgaacagga tgtaaaagac gttgacgtcc tgtacttccg tgagctgctg
    33901 gccggggtgg cgactaacac cgcatacctc gacggactga tgaagccgta cctgtcccgt
    33961 ctgctggaag aactgggcca ggtagaaaaa gcagtactgc gcattgcgct gtacgagctg
    34021 tctaaacgta gcgatgtgcc atacaaagtg gccattaacg aagcgatcga actggcgaaa
    34081 tcgttcggcg cagaagacag ccataagttc gtcaacggcg tactcgataa agcagcacct
    34141 gtgattcgcc ctaacaaaaa gtaatatcca agccggtaga ttcacggaag accgttccat
    34201 gatcgccggc cttttctttt ttatctgctg aggcgtaacg tatggcatgt ggcgagttct
    34261 ccctgattgc ccgttatttt gaccgtgtaa gaagttctcg tcttgacgtc gaactgggca
    34321 tcggcgacga ttgcgctctt ctcaatatcc ccgagaaaca gaccctggcg atcagcactg
    34381 atacgctggt ggcgggcaac cacttcctcc ctgatatcga tcctgctgat ctggcttata
    34441 aagcactggc ggtgaaccta agcgatctgg cagcgatggg ggccgatccg gcctggctga
    34501 cgctggcatt aaccttaccg gacgtagacg aagcgtggct tgagtccttc agcgacagct
    34561 tgtttgatct tctcaattat tacgatatgc aacttattgg cggcgatacc acgcgtgggc
    34621 cattatcaat gacgttgggt atccacggct ttgttccgat gggacgagcc ttaacgcgct
    34681 ctggggcgaa accgggtgac tggatctatg tgaccggtac accgggcgat agcgctgccg
    34741 ggctggcgat tttgcaaaac cgtttgcagg ttgccgatgc taaagatgcg gactacttga
    34801 tcaaacgtca tctccgtccg tcgccacgta ttttacaggg gcaggcactg cgcgatctgg
    34861 caaattcagc tatcgatctc tctgacggtc tgatttccga tctcgggcat atcgtgaaag
    34921 ccagcgactg cggcgcacgt attgacctgg cattgctgcc gttttctgat gcgctttctc
    34981 gccatgttga accggaacag gcgctgcgct gggcgctctc tggcggcgaa gattacgagt
    35041 tgtgttttac ggtgccggaa ctgaaccgtg gcgcgctgga tgtggctctc ggacacctgg
    35101 gcgtaccgtt tacctgtatc gggcaaatga ccgccgatat cgaagggctt tgttttattc
    35161 gtgacggcga acctgtcacg ttagactgga aaggatatga ccattttgcc acgccataaa
    35221 gatgtcgcga aaagtcgcct gaaaatgagt aatccgtggc atctgcttgc tgtcggattc
    35281 ggaagtggat taagcccgat cgttcctggc acgatggggt cgctggcggc gattcccttc
    35341 tggtatctga tgactttttt gccctggcag ctctattcgc tggtggtgat gctggggatc
    35401 tgtatcggcg tctatctttg tcatcaaacg gcgaaagaca tgggcgtgca cgatcacggc
    35461 agtattgtct gggacgaatt tattggtatg tggattacgc tcatggcgct gccgaccaat
    35521 gactggcagt gggttaccgc cggatttgtg attttccgta ttctggatat gtggaagccg
    35581 tggccgatcc gctggtttga tcgcaatgta catggcggca tggggatcat gattgacgat
    35641 attgtcgccg gggtgatctc cgcagtcatc ctgtacttta ttggacatca ctggccgctg
    35701 ggtattctgt cgtagttgtg caccgatgcc tgatgtgacg cttgtcacgt ctcatcaggc
    35761 ctgtatacct atttaaatcc tacgaccgga tgcggtttat acggcgtttc cagctcggcg
    35821 atttgttccg gcttcaaggt gatatccacc gcgtttagca gttcatcaag ctgttcctcc
    35881 cgagaagttc cgataatcgg tgcggcaatg cccggtttac tcaacaacca ggccagcgca
    35941 acttgtgctc gcgttgcacc aagttcttca ctgacgcccg ttaagcgttc tgcaatttgt
    36001 gcgtcatttt catcgctttc ttggtagaga tttttcccca cttcatccga caccagccgt
    36061 gcggtggttt ctccccaagg acgcgtcaga cggccccgcg ccagcgggct ccatggaatc
    36121 accgccacgc cttcctgata acacagcggc agcatctcgc gctcttcttc acgataaatc
    36181 agattgtagt gatcctgcat actgacaaac tgcgcccagc cgtgctgttt ttgtagttcc
    36241 agtgcttgag caaactgcga agcgtgcatg gatgacgcgc cgatataacg cgctttcccg
    36301 acttttacca cgtcgttcag ggcttccagc gtctcttcga tcggcgtgtt gtaatcccag
    36361 cgatgaattt gcaggatatc gacataatcc atgccgagac ggcgcaggct gtcgtcgata
    36421 gagcgcaaaa tttgtgcacg ggataatcct tcaggtaaat caccaacgcg atggaacact
    36481 ttggtcgcaa cgaccacgtc ttcacgacgg gcgaaatccc gcagtgcgcg accgacgatc
    36541 tcttcgctgc tgccatcgga atagctattg gcggtatcaa agaaatttat gccgccttcc
    36601 agcgcacgtt taatgatggg acggctgctc tcttccggca gtgtccatgc gtgattaccg
    36661 cgatctggct cgccaaaggt catacatccg aggcaaagtc gggaaacgcg aaggtcggtt
    36721 tttcctaagg ggttgtattg catgctgcca ctcctgccat gaataatttc ttaagcatag
    36781 caggagtgga gtagggatta tgccagccag gctttgattt tggcttccat accggtggca
    36841 tcgaggccga gttcggcgcg catttcttcc tgagttcctt gtggaataaa gaagtccggc
    36901 aggccaatgt tcagcacggg tactggttta cgatgggcca tcaacacttc gttcacgccg
    36961 ctgcctgcac cgcccataat ggcgttttct tctacggtaa ccagcgcttc atggctggcg
    37021 gccatttcca gaattaacgc ttcatcaagc ggtttcacga aacgcatatc gaccagcgta
    37081 gcgttcagcg attcagcgac tttcgccgct tctggcatca gcgtaccaaa gttaaggatc
    37141 gccagtttct caccacgacg cttcacaatg cctttgccaa ttggcagttt ttccagtggc
    37201 gtcagttcca cgccaactgc gttgccgcgc gggtagcgca ccgcggacgg gccatcgtta
    37261 tagtgatagc cggtatagag catctggcga cattcgtttt catcgctcgg ggtcataatg
    37321 accatttccg gtatgcagcg caggtaagag agatcaaaag cgccctggtg ggtttgaccg
    37381 tcagcgccaa caatgcccgc acggtcgatg gcgaacagga ccggaagctt ttgaatcgcc
    37441 acgtcatgca gcacctgatc ataggcgcgt tgcaggaagg tggagtagat cgcgacaatg
    37501 ggtttgtagc ctccaatcgc cagacccgca gcaaaggtta ctgcgtgttg ctcggcaatt
    37561 gccacgtcaa agtagcgatc cgggaattta cgtgaaaact cgaccatgcc ggaaccttca
    37621 cgcatcgccg gagtaatcgc catcagcttg ttatctttcg ctgcggtttc gcacaaccag
    37681 tcgccaaaga tttttgaata gcttggtaaa ccgccgctac ttttcggcag acaaccgctg
    37741 gagggatcaa atttaggcac ggcgtggaag gtgattgggt ctttttctgc cggttcataa
    37801 ccacgacctt ttttggtcat gatatgcagg aactgcgggc ctttcaggtc gcgcatgttc
    37861 ttaagcgtgg tgataagccc cagcacatcg tgaccgtcca ccgggccgat gtagttaaag
    37921 cccagctctt caaacaacgt gccaggcact accatgcctt taatatgttc ttcggtacgt
    37981 ttgagcagct ctttaatggg tggcacgcca gagaaaactt tttttccgcc ttcgcgcagt
    38041 gaagagtaaa gcttaccgga aagcagctgc gccagatggt tgttgagcgc gccaacattt
    38101 tcggaaatcg acatttcatt gtcgttgaga accaccagca tatcaggacg gatatcgccc
    38161 gcgtgattca tcgcttcaaa cgccatgcca gcagtaatcg cgccatcgcc aatgacacag
    38221 acggtgcggc gatttttgcc ttctttctcg gcagcaaccg caataccaat tccggcactg
    38281 atggaggttg atgaatgccc gacgcttaat acgtcatatt cgctttcgcc gcgccacggg
    38341 aacgggtgca ggccaccttt ctgacggatg gtgccgattt tgtcgcggcg cccggtcaaa
    38401 attttatgcg gataagcctg atgccccaca tcccagatta actggtcaaa cggggtattg
    38461 tagacatagt gcagcgccac ggtcagttcg accgtgccca gcccggaggc gaagtgcccg
    38521 ctggaacggc tcacgctgtc gagtaaatag cggcgcagtt cgtcgcagag tttcggtaaa
    38581 ctctctttcg gcaacagtcg taactcctgg gtggagtcga ccagtgccag ggtcgggtat
    38641 ttggcaatat caaaactcat caggggccta ttaatactta ttgtttattt attacgctgg
    38701 atgatgtagt ccgctagcgc ttccagtgcc gaggtatcga atgactgttc agtcagttgt
    38761 ttcagcgact gacgggcatc gtcgatcaga tcccgggctt tcttccgggc ttgctcaaga
    38821 cccagaagtg cagggtaggt acttttacca agttgctggt cggcaccctg gcgttttccc
    38881 aacgttgcag tatctcccac cacatccagg atgtcatcct gaacctggaa ggcaaggccg
    38941 atgctctctg cgtacttgtc gagtactggc agagcacgac gtcctttatc tccggcgctt
    39001 aatgcaccaa ggcgaacggc ggcgcgaatc aatgcgccgg ttttatgacg atgaatacgc
    39061 tcaagcgcgt ccagaggtac gtgtttgcct tcagcgtcta aatctaatgc ctgaccaccg
    39121 cacattccgg caataccgct ggcgctcgcc aactcagaaa tcatcgaaat tctgtcgcga
    39181 tctgacactt ccggcatatc ggcatcgctt agaatcgaga acgccagcgt ttgtaaagcg
    39241 tcaccagcga gaatcgcgtt tgcttcgcca aacttcacat ggcaggtcgg caaaccgcga
    39301 cgcagatcgt catcatccat cgccggtaaa tcatcatgaa ttaatgagta agcgtggata
    39361 cactctacgg cggcagcggg tgcgtccagt gtgtttgtgc taacgccgaa catatgacca
    39421 gtggcataaa ccaggaaagg tcgcaggcgc ttaccaccta ataatgcgcc atactgcatg
    39481 gtttcgacca cgggagtgtt ctgaaagggc agtggggcga taaaacggct cagcgcctgg
    39541 ttggcctgct taacgcaggc ttcgagttgc tgcggaaagt ccattactca ttgtccggtg
    39601 taaaaggggt tagagaggcg tcttcattgt cagacagcag aatttgtacg cgctgttcgg
    39661 cttgttgtaa tttagcctgc ccctgacgtg ccagctgcac gccgcgttcg aactcgttca
    39721 gcgcctcttc cagcggcagg tcgccacttt ccagacgggt tacaatctgt tccagctcgc
    39781 tcagcgcctt ttcaaagctg gcgggagcct catttttctt cggcataatg aatgtctgac
    39841 tctcaatatt tttcgccccg tcatggtaac ggactcaggg caaatagcaa ataacgcgca
    39901 atggtaaggt gatgtgcgca gcaaagcgat gttagtggta tacttccgcg cctggatgca
    39961 gccgcaggtg tgggctgctg tatttttccc tatacaagtc gcttaaggct tgccaacgaa
    40021 ccattgccgc catgaagttt atcattaaat tgttcccgga aatcaccatc aaaagccaat
    40081 ctgtgcgctt gcgctttata aaaatcctta ccgggaacat tcgtaacgtt ttaaagcact
    40141 atgatgagac gctcgctgtc gtccgccact gggataacat cgaagttcgc gcaaaagatg
    40201 aaaaccagcg tctggctatt cgcgacgccc tgacccgtat tccgggtatc caccatattc
    40261 tcgaagtcga agacgtgccg tttaccgaca tgcacgatat tttcgagaaa gcgttggttc
    40321 aatatcgcga tcagctggaa ggcaaaacct tctgcgtacg cgtgaagcgc cgcggcaaac
    40381 atgattttag ctcgattgat gtggaacgtt acgtcggcgg cggtttaaat cagcatattg
    40441 aatccgcgcg cgtgaagctg accaatccgg aagtgactgt ccatctggaa gtggaagacg
    40501 atcgtctgct gctgattaaa ggccgctacg aaggtattgg cggtttcccg atcggcaccc
    40561 aggaagatgt gttgtcgctc atttccggtg gtttcgactc cggtgtttcc agttatatgt
    40621 tgatgcgtcg cggctgccgc gtgcattact gcttctttaa tctcggcggc gcggcgcatg
    40681 aaattggtgt tcgtcaggtg gcgcattatc tgtggaaccg ttttggtagc tcccaccgcg
    40741 tgcgttttgt cgccattaac tttgagccgg tcgtcggtga aattctcgag aaaatcgacg
    40801 acggtcagat gggcgttatc ctcaaacgta tgatggtgcg tgccgcgtcc aaagtggcag
    40861 aacgttacgg cgtacaggcg ctggttaccg gtgaagcgct cggccaggtg tccagccaga
    40921 cgctgaccaa cctgcgcctg attgataacg tctccgatac gctgatcctg cgtccgctga
    40981 tctcttacga caaagagcac atcatcaacc tggctcgcca gattggcacc gaagactttg
    41041 cccgcacgat gccggaatat tgcggcgtga tttccaaaag cccgacggtg aaagcggtta
    41101 aatcgaagat tgaagcggaa gaagagaagt tcgacttcag cattctcgat aaagtggtgg
    41161 aggaagcgaa taacgttgat atccgcgaaa tcgcccagca gaccgagcag gaagtggtgg
    41221 aagtggaaac cgtcaatggc ttcggcccga acgacgtgat cctcgatatc cgttctatcg
    41281 atgaacagga agataagcca ctgaaagtcg aagggattga tgtggtttct ctgccgttct
    41341 ataaactgag caccaaattt ggcgatctcg accagagcaa aaactggctg ttgtggtgtg
    41401 agcgcggggt gatgagccgc ctgcaggcgc tctatctgcg cgagcagggc tttaacaatg
    41461 tgaaggtgta tcgcccgtaa tatgtggttg taacgtcgca tctggtcaga tgcgacgctt
    41521 accgcatccg acactactcg taataattat aaatccctgc cgccatcacc agttgtgatg
    41581 ccacttcatg ggctttctcg cgcccaacca gcaggtcgat aattttcaga ccaaagtcga
    41641 tagctgtacc cggcccctgg ctggtcagca attttacccg tgcatcccag acgacgcgct
    41701 tgtcctgcca ttgttcggcg ggaattttgt ctttcagcgt tgggaagccg gtcatattgc
    41761 caatcgggaa gatatcgtgc gggaccagca cggtggctgg cgcggcgcaa atagccgcga
    41821 cgatacgccc ggaacggtgg aactgtttaa cggtttcaac cagcagggtg ctatcgcgaa
    41881 aacactctgc gcctttgatg ccaccaggca gcacaatcac gtcatattcg ccatcagcca
    41941 cttcgaccag cggcgcatcc gccagcagct tcacgccgcg cgagcaggta atcgccaggt
    42001 taccatcgct ggcgacgctg gcagtggtga ctttgatacc gccgcgaacc aagaggtcga
    42061 tagtggtgac ggcttcagtc tcttcactac caggggcgag gcaaaccagt gccgatgcgc
    42121 tcatattcac tctcctttct ttttaccatt tcaaacaggc gggtgttttc cggtacggca
    42181 atcccatgcg cgcgggcgcg gcgtaagaga aaaccattga tatagtcgat ttcggtgtgg
    42241 cgcagcgcgc ggatatcctg caacatcgac gagatatttt ccgctgttgc atcaatcacc
    42301 tgcatcacgt aatcacgcaa atcttctgct gaagtatgat gcccttcgcg ttcgatcact
    42361 gccgcgactt cttcgcatat ctgcataatt tcttgcggat gatgacgtaa ttcaccattc
    42421 gggcaattcc agatggcggt cagtggatta atcacacagt tgactgccag cttgcgccac
    42481 agctcggcgc gaatattgtt atgccacgcg acgtcaggca atacggtttg caaaatatcc
    42541 gccagataac tgtaatcgcc gtcctgttgc cgtgccggac caatatgcgt gataccgttt
    42601 gccacatgaa taatgacatt gccgtcgcgg cgggcggcat gggtggtggt gcccatcagt
    42661 aatggctgct gaatgttttg caactcttcg atggtgccca tgccgttgtg aattaacagt
    42721 attggcgtgg ttacaggcag tgtggacgcg aggcttttga cggcatcgga aacctgccat
    42781 gctttcagcg tcaccaggag cagatcgctg gtggcgagaa aatcgggatc gttggcggtc
    42841 agcgattcat taaatatcga accatctgtc tcaaccagat tcacactaca ataaggttgc
    42901 ggtacgcgca gccagccctg aacgtcgtga ccctgtttac aaagtgctgt aagccataat
    42961 tgccctaagg caccgcatcc caatacggta attttcattg ttcctcctca cccgcaacca
    43021 ctccgggtgt tcaataaggc tatcccttaa ttgtgcatgc tgttgcgact atgcacaatt
    43081 aagggatacg tcctggtgca ggactgttgg ttatttaact ttgcaggtat tatgcttcgc
    43141 atcaaaaatg aagggagagg aaaagatgcc atctttcgat attgtctctg aagttgatct
    43201 tcaggaagca cgtaacgcgg tcgataacgc gagccgcgaa gtggagtccc gttttgactt
    43261 ccgtaacgtt gaagcctcat ttgagctgaa tgacgccagc aaaaccatca aagtgttgag
    43321 cgagtccgac ttccaggtca atcagttgct ggatattctg cgtgccaagt tgctgaagcg
    43381 cggcattgaa ggcagttcac tggatgtacc ggaaaatatc gttcatagcg gtaaaacctg
    43441 gtttgtggaa gcgaaactga aacagggcat tgagagcgcg actcagaaga aaatcgtcaa
    43501 aatgatcaaa gacagcaaac tgaaagtgca ggcgcaaatt cagggcgatg agatccgtgt
    43561 gacgggcaaa tctcgtgatg atttacaggc tgtcatggcg atggtacgtg gtggcgatct
    43621 gggtcagccg ttccagttca aaaacttccg cgattaatcg cgacaacctg cgctttgttc
    43681 atgtcagatg cggcatgaac gcctgattcg gcctacaaag gtttgtaact caggaactta
    43741 gtaggcctga taagcgtagc gcagcaggca atttcgcctc gcttttatgc ctggcgaatt
    43801 gcctgttcaa cctcaaagcg attcgtcact ttgctgtcga ttttcacata agctgaatgt
    43861 tcttcttctg caatcaacac ttctttgatg ccttcagttt ccagcaaacg cacttttaac
    43921 gcctcgtttg cggcaatgtt cgccgggatt tcaatgcgca agctgctgac atacggcggt
    43981 tctttcatgg tactggcgac tgccagccac actgcggcca gcattgcgcc agcgagaaat
    44041 actccctgac cgtcaaacat gccgtcaatc cagccgccca gcgaaccgcc aatcgccacg
    44101 ccaagaaact ggctggtgga gtaaacaccc atcgccgtac ctttgtaacc tgctggcgat
    44161 tctttactga taagtgaagg cagaagggct tccatcaaat taaacgccac aaagaaaagc
    44221 tgcacgccga ccaccagttg ccagaactgc gtttgtgcgt tccacaacac aatttccgca
    44281 accacgatca acccgacgca gaagacaaag acttgcttca ttttgcgctt aacttcagcg
    44341 tagataatga aaggcacgac cgagccaaag gcgattaaca tcgttgccag gtagaccttc
    44401 cagtgttcag ccgccgggaa ccccgcatca gccatctgtc cgggcagggc aacaaaggtc
    44461 gacatcagca aaatatgcag acacataatg ccaaagttga gtttcagcag ccgcggttcc
    44521 gccagcactt tactgaaact gccttttacc attccggact cacgattaag tacatgagtg
    44581 ctactgttgg gcacaaccca aatggtcaac gcaatgccgg ttgttgccag aatagcgatc
    44641 atccagaaca gcacgtgcag cccaagtttg tgagtgatga tcgggccaag caccatcgca
    44701 atggcaaagg taatgccaaa gctcacgccg ataaacgcca tcgctttggt gcggttttgt
    44761 tcgcgcgtga gatcggaaag cagcgccata acggctgcgg caatcgcacc ggagccttgt
    44821 agcgcccggc ccagaataat tccccagatg gagtcagaga gcgcagcgat aacgctaccg
    44881 gcggcaaaca ccgccagccc accgacaatt aatggtttgc gaccaatgcg gtctgaaagc
    44941 aggccaaacg gaatctgaaa aacggcctga gtcagaccat aaataccaat ggcaataccg
    45001 attaatgctt cgctggcacc ttgcagagcc atgccgtacg tggtcagaac cggcagaacc
    45061 atgaacatgc ccagcatgcg taatgaaaat acggtcccta aaccccaggt cgcgcgccgc
    45121 tcacctggcg tcattttata atcgttcatt accacctctg ttttaaattc gcgactagtg
    45181 taaagcggca aacgaatggg gtaaacatgc ggatttttta gtaaatattt cgagagggat
    45241 atgattctaa tgctaagaaa aaaggtgccg tagcaccttt ttaactgaga ggttgtgtta
    45301 ccacacagca gccagcagcg tatgcgagtc cggcaccata aaatcaacgg acatcatcac
    45361 cgagagggca gtgatagcga tgatagagaa accgaacagc ttgcgcgccc agattctgtc
    45421 atcagcaact ttatagccgc gcagagccat gcctaaccac cagacgctca ccgcagcggc
    45481 gaccaccaga tatttatacc cagcgtagcc gccaagagag agcatcagcg tggcaacggc
    45541 aaaggcgatg atatacagcg tgatgtgatt cttcgccacc gaaatgcctt tcaccaccgg
    45601 cagtaccgga atgtttgccg cctgataatc cttaaagcgg aaaatggcta tggcataaga
    45661 gtgaggcatc tgccacaggc tgaagatagc caacaggatc gctgcgccgc tatcgaactc
    45721 gccggttacc gcacagtaac cgatcaccgg aggcgcagcg ccggagagcg aaccaatcaa
    45781 tgtgccgtag acagaatgac gtttcatgta caggctataa acgccgacat aaaccacaaa
    45841 gcccatcacc cccagccagc aggccagcgg attcgcgcca aaccacagca gcataaagcc
    45901 agcaataccc agcaaggtgg cgtacaccag cgagacagca ggagagatca ggcctttaac
    45961 cagcacccga ttcttcgtcc tttccatctt tctgtcgata tccctgtcga tgtagttgtt
    46021 aaacacacaa cccgacgcca caaccagtga caccccaacc agcgtgtaga taaacagggg
    46081 ataatcaatg ctgccctttg aggccagcaa gaatccccca atcaccgaga tcaggttgcc
    46141 aaagatgatg cctggtttcg ttacttgcag gtattgctta aatatcataa ccgccgctct
    46201 tagtgcatca tcatgttgta gttgaggttc cacataatcc agatggagcc cacaaccagg
    46261 atggcgatga ttagcacggt gaagacaaac gccgtcatat tccagccttc atctgatttg
    46321 gtattcatgt gcaggaagca caccagatgc accagaattt gtaccactgc cattgccagg
    46381 attgttccca gaattacggc cggagaggca gcccctgtca tcaccatcca gaacggaatt
    46441 accgtcagga ttatcgacag gataaagcct gtcatgtagg tctttacgct gccatgggat
    46501 gcgccgctgc ttgcgttaga atgactcatt acatcgcccc catcagataa acaacagtga
    46561 acacacagat ccaaaccaca tccaggaagt gccagaacag gctcaggcac atgatgcggg
    46621 tacggttagt gctggtcagg ccgcgacggg cgatttgcac catcagcacc gccatccaga
    46681 taagaccgga agtgacgtgc agaccgtgcg tgccgaccag cgcaaagaat gctgacagga
    46741 agccgctgcg atccggaccc atgccgttaa caatcaggtg atggaattca tagatttcca
    46801 tcccgataaa tccggcacca aacaaccatg tcaacgccag ccaggagatc acctggcttt
    46861 tgttgttttt gtacatggcg atagccgcca tgccataggt gatggagctg aacaacagca
    46921 agaaagtttc aaccagaacg aacggcagtt cgaaaatgtc cttacctgtc gggccgcctg
    46981 cggtgccgtt caccagaacg gcataggtag caaacaagat agagaacaga atgcagtcgc
    47041 tcatcaggta gatccaaaat ccgaaaattt tggttccgcc tgcatcgtgg tgcccgtgtt
    47101 cgtgcgcgtg ggcagtcgcg tgcgtcaaag tatcagttgc catttttcag ccctgcctta
    47161 gtaatctcat cgaaatgctg gttttccagt ttttcgattt ctgccaccgg cacgtagtaa
    47221 tccacgtcct cgtcgaagct tttcacgatc caggtgatga tcatgcctgc gaagccaaca
    47281 atcgctagcc accagatatg ccagatcatg gcgaaaccga agatggtgga gaaagccgca
    47341 atgacgatac cggcaccgct gtttttcggc atatgaattt cttcatagtg gtcaggcttt
    47401 ttgtacgctt cgcctttctc tttcatttcc cagaatgcat cacgttcgtg aacgtgcggc
    47461 acaacggcaa agttatagaa cggaggcggg gaagaggttg cccactccag cgtacggcca
    47521 ccccacgggt cgccagtcag gtcacggttc tggtcgcggt cacgaataga aacgtatatc
    47581 tgaataacga ggcagagaat acccagcgca atcagtaccg caccgctggc tgcaatcatc
    47641 agcatggtgt ggaactgcgg gtcaatctgc tggctcaaac gacgggtcat gcccatgaag
    47701 cccagcgcat acagtggcat aaaggcaacg aagaagccga tgatccagaa ccagaacgcg
    47761 cgtttacccc aggtttcgtt cagtttgaaa ccgaacgctt taggccacca gtaggtcatc
    47821 cctgcgaagc agccgaagac cacgccgccg atgatcacgt tatggaagtg cgcaatcagg
    47881 aacaggctgt tatgcagaac gaagtccgcg cccggtactg ccagcagcac gccagtcata
    47941 ccgcctaccg agaaggtaac gataaaaccg atggtccaca gcatcgcaga atggaacacg
    48001 atgcggccct gatacatggt gaacagccag ttgaagatct tcaccccggt agggatggcg
    48061 ataatcatcg tggtgatacc aaagaaggcg tttacgttcg cgcccgcacc catcgtaaag
    48121 aagtggtgca gccagacgat gaacgacagc acggtgatac agacggttgc ccataccagc
    48181 gaggtataac caaacagacg tttacgcgag aaggttgccg caatttcgga gaacacaccg
    48241 aatacaggca ggatcaagat gtaaacttcc gggtggcccc aggcccaaat caggttgata
    48301 tacatcatca tgttgccacc catatcgttg gtaaagaaat gggtgcccag atagcgatcc
    48361 agggtcaaca acgcgacggt aaccgtcaga attgggaagg aagcaataat cagtacgttt
    48421 gcgcacagtg atgcccaggt aaatactggc atcttgaaca tggtcatgcc cggtgcgcgc
    48481 atcttcagaa tggtaacgaa gaagttgata ccggtaagcg tcgtacctat accggatagc
    48541 tggagactcc atatccagta atcgacaccg actcccggac tgtactctat tcccgatagc
    48601 ggtggatagg ccagccagcc ggtctgcgca aattcgccca cgccgagaga aacgttaacc
    48661 agaatcacac caacaacggt aaaccagaag cttaagttgt tgaggaacgg gaacgcaacg
    48721 tcacgcgcgc cgatctgcag cggaaccacc aggttcatca gaccgataac gaaaggcatc
    48781 gccacgaaga agatcatgat cacgccgtgt gcggtgaaga tctgatcgta gtggtgaggt
    48841 ggcaggaagc ccgcttcgcc cgcagaggca agggcctgct gactacgcat cataatggcg
    48901 tcagcaaaac cacgcagcaa catcacaatc gccacgatga tatacatgat accgagacgt
    48961 ttatggtcaa cggaggtcag ccactctttc cacaggtagg tccacttacc gaagtaagtg
    49021 atcaggccaa cgagcgccag acctcccaaa ataatgccag cgatcgtaac catgacgata
    49081 ggttcatgga acgggactgc atcaagtgat aattttccga acatctttat tcttcctcaa
    49141 cccctttaat gggcggattc cgcgtggctc atgtccatgc cttccatacc ttcatgtgcg
    49201 ctgtgctcac cttctggctg ggtcatgtcc atgctcttac cgtgagccat aaacttgtta
    49261 atcacatcgg caaacaagtc tggtttcacg ttggagaaat attccacctg gttgtattcg
    49321 ctaggcgcgg ccagtttttc gaacgctgcc atgtcagaca tgctgttcgg cgactgtttc
    49381 gcttttgcga cccattggtc gaatgcggcg cgatccggtg ttgcaatagc tttgaacttc
    49441 atgcctgaga agcccgggcc gctgtagctg gcggagatac cgtcataagt accgggttcg
    49501 ttggcgatca gatgcaggcg agtctgcata ccggccatgg cataaatctg gctacccaga
    49561 cgcggaatga agaaggagtt catcacggag ttggaggtca ctttgaagta caccggagtg
    49621 ttcgccggga aagcgatttc attcacggtt gcaatgccct gttccgggta gatgaagaac
    49681 catttccagt ccatggaaac cacttcgatg gtaatgggct tctcgtcgtg tgccagcggc
    49741 ttgctaggct caagagcgtg agtggttttc caggtcagta ccgcaaggaa gatgatgatt
    49801 aagataggta ccgtccagac cacagcttcc actttattgg agtgtgacca gttcgggctg
    49861 tacttagcat ctttattgct cgcacggtac ttccaggcga aaccaacagc catcaagatt
    49921 gcgggaataa cgacaatcaa catcaggcca aatgccgtca gtatcagtga acgttgctcc
    49981 agaccaatct gtcctttggg atctaacagc gcagaattac agccactgag caatacagtg
    50041 cctgcaaata atgacaacca tcccaaactt ttattgtatt tcctgagtct catttaacga
    50101 cctcaattcc acgggatctg gtggcgttta aagtgtgtgg gcattttacg ggaaggttac
    50161 attactgtaa acatgattaa attcctgtta cttggatttg gctatcaggt cacatatgtt
    50221 gcaaaacata tcaagttgat tttaagaagc tgttgcaaaa gggcgttata acgaaaggga
    50281 agtgcagaag gagtttgggc gggcaattgg tataatcaat ataaaataaa acaattattt
    50341 aacaaataac tatcattagg gtgacaactg ggtggtgaga aaataaggac tcatcagctg
    50401 aatcgtgtaa aaaaaataga attcataaat ggcgtcaata atttccagac gctaagccgc
    50461 acaaaagaac aaatatcaat aagcgatgct gatgtttatt tagccgtaat aattacggcg
    50521 agtgattact acagctaaat aatatttaca gattacgtca gatgtgtttt tcgtagcgcc
    50581 agataatcca gcaaaccacc aagcacgacg ccagagaggg cgactaaaac cccgacttcc
    50641 agcagcgcag gcaggaaaga gaagtgcgtc aaatccagcg cgtccatcgt caacagcagt
    50701 aaccacacgg ccaacaggct gatgcccgcc gccagtgtcc acatggcaaa ggcataacct
    50761 gcaggatatt cggtacggga gataaagttg tcatttactc gtgtatattc aagcgtctgg
    50821 cggcaaacca gcagcaaaat aagccctggt acggcagcgg cgacggagaa tagatagaat
    50881 gtcgaccagc cgtgtgcttc aacaaaccaa cccgccacgg ggccgacata aactcgccct
    50941 acagcagaaa gcgctgagag cagggcaaat tgagtagcgg aaaatgactt attacacagc
    51001 gtcattaaca gcgcgacaaa ggctgatgta cccatcccgc cacagaggtt ttcgaaaaag
    51061 acggctgcac ccatgctgta gagatgctta tcagtaatcg acagcagcca gtaaccggcg
    51121 ttagatgcac cttgtaaaat gccgaaaatc agcagtgcac ggaacagcga caggcgctgc
    51181 atcaaaatcc caccgtacaa tgcgccaaca atggtcgcca gtaagccaag cgttttgtta
    51241 accacgccta cttcacccgc atcaaacccg acgccgcgaa tcaaaaacgt ggttgtcagg
    51301 ctcatagcga atgcgtcgcc cagcttatac agcacgataa gaagcaaaat aagccaggca
    51361 ttattgcgac caaagaaatc tcgcagaggt gcaacaaccg cttgttccag cgttttgggc
    51421 acaggaatgg tgtcggtggg ttctggtgca agcaacgtcg cgataataca ggggatcaac
    51481 agcgccgcca tcaaccagta catgccctgc cagcccagcc atttatctgc cagccacagg
    51541 gctaagccgc cggaaaccag catccctaaa cggtaaccca gcacgctgat tgccgcgccc
    51601 gcaccacgtt cttctgccgg gagcacatcg gttttccacg catcgaagac aatatcctgg
    51661 gaggcagagc aaaaagcgat caccaccgcc agtgccgcca tccagcggag ctgggtgcct
    51721 ggttcgagaa aacccatcgc cgcaatggcg actaataaca gaatttgcgt ggcgagcagc
    51781 caaccgcgcc gccgcccgaa aaatgggggc gtgtagcggt ccatcagtgg tgaccagagg
    51841 aatttaaaaa cgtaagcctg gcctaccaga gagaagaaac caatggtttt gagatcgata
    51901 ttctcgaccg tcatccaggc ctgtaaggtg ccggacgtca gggcgagcgg tagcccggaa
    51961 gcaaaaccca ggatcagcaa tatggctgaa cgcggctgtt gaaaaatacg taaatattga
    52021 ctggacatgg gcgtctacag gcccggcttg caccgggcca gagggcagaa attaacgcgc
    52081 gttctgcttg atgaattcgt ggatgctggt gtcctgagac atatcagcga tggtatcggt
    52141 cagcacactg ttaaccgcat cggcgatatt tttgttggag gcctggaacg caccttcaac
    52201 gttgtagctg gcacgatagt ttttggtcat tttgttgcca ttctgcgcgg tagcgatgat
    52261 ggcgatatcc gctttggtcg cgatgttgta gcgcacgttg ccctgggaca cgtcagcata
    52321 cagttggcta acgatgattt gcagattaac cgggccattc ggaccaacca tgtatccacg
    52381 ggcggtcatt tgtttttcca gcacttcttg cagcaggaaa cgcagatcgc gggaggcggt
    52441 cagggtaacg atttgattat cgcgggtgac ttttgccagc gcctgatcgg tacgctgatc
    52501 ggcaccatta atgcttacgg tgacgcccat caggcttgga tcctgctgtg gcagtgtaat
    52561 cgtcggggaa acttcgatag ttgttggcgg ttttgcgcat cctgcaagca taaacagagc
    52621 aactaacggg aagaggattt ttttgaacat gttcgggctc tcagagactc ttaagcgtgt
    52681 ttggtaaaaa ttcccgccat cataacattg ccaacggcga ggggaagtgg gtaaggcatg
    52741 taaattcatc atgttgacga aataatcacc cctggtaaaa gaaacgctga tgcgaggcct
    52801 gtgtttcaat ctttaaatca gtaaacttca tacgcttgac ggaaaaacca ggacgaaacc
    52861 taaatatttg ttgttaagct gcaatggaaa cggtaaaagc ggctagtatt taaagggatg
    52921 gatgacatct cagcgttgtc ggaggagata tttcatgatg atacgtgagc ggatagaaga
    52981 aaaattaagg gcggcgttcc aacccgtatt cctcgaagta gtggatgaaa gctatcgtca
    53041 caatgtccca gccggctctg aaagccattt taaagttgtg ctggtcagcg atcgttttac
    53101 gggtgaacgt tttctgaatc gtcatcgaat gatttacagt actttagcgg aggaactctc
    53161 tactaccgtt catgcgctgg ctctgcatac ttacactatt aaggagtggg aagggttgca
    53221 ggacaccgtc tttgcctctc ctccctgtcg tggagcagga agcatcgcgt aaaaacgcat
    53281 ttgcaactgt cggcgctttt ccagtatgtt gctaaagatt ttatgaaaaa cggcctgcgg
    53341 gccgttttgt tttgtctgga ttttgcgctt tttgcccagc attcagacga aaatcgcccg
    53401 ggaattgtga aaaaatacgc gacagcgcgc aataaccgtt ctcgactcat aaaagtgatg
    53461 ccgctataat gccgcgtcct atttgaatgc tttcgggatg attctggtaa cagggaatgt
    53521 gattgattat aagaacatcc cggttccgcg aagccaacaa cctgtgcttg cggggtaaga
    53581 gttgaccgag cactgtgatt ttttgaggta acaagatgca agtttcagtt gaaaccactc
    53641 aaggccttgg ccgccgtgta acgattacta tcgctgctga cagcatcgag accgctgtta
    53701 aaagcgagct ggtcaacgtt gcgaaaaaag tacgtattga cggcttccgc aaaggcaaag
    53761 tgccaatgaa tatcgttgct cagcgttatg gcgcgtctgt acgccaggac gtcctgggcg
    53821 acctgatgag ccgtaacttc attgacgcca tcattaaaga aaaaatcaat ccggctggcg
    53881 caccgaccta tgttccgggc gaatacaagc tgggtgaaga cttcacctac tctgtagagt
    53941 ttgaagttta tccggaagtt gaactgcagg gtctggaagc gatcgaagtt gaaaaaccga
    54001 ttgttgaagt gaccgacgct gacgttgacg gcatgctgga tactctgcgt aaacagcagg
    54061 caacctggaa agaaaaagac ggcgctgttg aagcagaaga ccgtgtgacc atcgacttca
    54121 ccggttctgt agacggagaa gagttcgaag gcggtaaagc gtctgatttc gtactggcga
    54181 tgggtcaggg tcgcatgatc ccgggctttg aagacggtat caaaggccac aaagctggcg
    54241 aagagttcac catcgacgtg accttcccgg aagagtacca cgcagaaaac ctgaaaggta
    54301 aagcagcgaa attcgctatc aacctgaaga aagttgaaga gcgtgaactg ccggaactga
    54361 ctgaagaatt catcaaacgt ttcggcgttg aagatggttc cgtagaaggt ctgcgcgctg
    54421 aagtgcgtaa aaacatggag cgcgagctga agagcgccat ccgtaaccgc gttaagtctc
    54481 aggcgatcga aggtctggta aaagctaacg acatcgatgt accggctgcg ctgatcgaca
    54541 gcgaaatcga cgttctgcgt cgccaggctg cacagcgttt cggtggcaac gaaaaacaag
    54601 ctctggaact gccgcgcgaa ctgttcgaag aacaggctaa acgccgcgta gttgttggcc
    54661 tgctgctggg cgaagttatc cgcaccaacg agctgaaagc tgacgaagag cgcgtgaaag
    54721 gcttgatcga agagatggct tctgcgtacg aagatccgaa agaagttatc gagttctaca
    54781 gcaaaaacaa agaactgatg gacaacatgc gcaatgttgc tctggaagaa caggctgttg
    54841 aagctgtact ggcgaaagcg aaagtgactg aaaaagaaac cactttcaac gagctgatga
    54901 accagcaggc gtaatttacg tagcataacg cgctaaattc gcacaaaggc ccgtcaccgc
    54961 caggtggtgg gctttttttt gtcatgaatt ttgcatggaa ccgtgcgaaa agcctctttc
    55021 ggtgttagcg taacaacaaa agattgttat gcttgaaata tggtgatgcc gtacccataa
    55081 cacagggact agctgataat ccgtccataa ggttacaatc ggtacagcag gttttttcaa
    55141 ttttatccag gagacggaaa tgtcatacag cggcgaacga gataactttg caccccatat
    55201 ggcgctggtg ccgatggtca ttgaacagac ctcacgaggt gagcgctctt ttgatatcta
    55261 ttctcgtcta cttaaggaac gcgtcatttt tctgactggc caggttgaag accacatggc
    55321 taacctgatt gtggcgcaga tgctgttcct ggaagcagaa aacccagaaa aagatatcta
    55381 tctgtacatt aactctccag gcggggtgat tactgccggg atgtctatct atgacaccat
    55441 gcagtttatc aagcctgatg tcagcaccat ctgtatgggc caggcggcct cgatgggcgc
    55501 tttcttgctg actgcagggg caaaaggtaa acgtttctgc ctgccgaatt cgcgcgtgat
    55561 gattcaccag ccgttgggcg gctaccaggg ccaggcgacc gatatcgaaa ttcatgcccg
    55621 tgaaattctg aaagttaaag ggcgcatgaa tgaacttatg gcgcttcata cgggtcaatc
    55681 attagaacag attgaacgtg ataccgagcg cgatcgcttc ctttctgccc ctgaagcggt
    55741 ggaatacggt ctggtcgatt cgattctgac ccatcgtaat tgatgccaga ggcgcaactg
    55801 tgccgctata cttatccagg gcggcacaac gctgtaagcg gcttgcgcct gagaatggca
    55861 tttgcgtcgt cgtgtgcggc acaaagaaca aagaagaggt tttgacccat gacagataaa
    55921 cgcaaagatg gctcaggcaa attgctgtat tgctcttttt gcggcaaaag ccagcatgaa
    55981 gtgcgcaagc tgattgccgg tccatccgtg tatatctgcg acgaatgtgt tgatttatgt
    56041 aacgacatca ttcgcgaaga gattaaagaa gttgcaccgc atcgtgaacg cagtgcgcta
    56101 ccgacgccgc atgaaattcg caaccacctg gacgattacg ttatcggtca ggaacaggcg
    56161 aaaaaagtgc tggcggtcgc ggtatacaac cactacaaac gtctgcgcaa cggagatacc
    56221 agcaatggcg tcgagttggg caaaagtaac attctgctga tcggtccgac cggttccggt
    56281 aaaacgctgc tggccgaaac gctggcgcgc ctgctggacg ttccgttcac catggctgac
    56341 gcaaccacgc tgaccgaagc cggttatgtg ggcgaagacg ttgaaaacat cattcagaag
    56401 ctgttgcaga agtgcgatta cgacgtacag aaagcgcagc gcgggattgt ctacatcgat
    56461 gaaatcgaca agatttctcg taagtcagac aacccgtcca ttacccgaga cgtttccggt
    56521 gaaggcgtac agcaggcact gttaaaactg atcgaaggta cggtagctgc tgttccgccg
    56581 caaggtgggc gtaaacatcc gcagcaggaa ttcttgcagg ttgatacctc taagatcctg
    56641 ttcatctgtg gcggcgcatt tgctggcctg gataaagtga ttgccaatcg tgttgaaacc
    56701 ggctccggca ttggttttgg cgcgacggtg aaagccaagt ccgacaaagc cagcgaaggt
    56761 gaactgctgg cgcaggttga accggaagat ctgatcaagt ttggtctgat ccctgagttc
    56821 attggtcgtc tgccggttgt cgcaacgttg aatgaactga gcgaagaagc tctgattcag
    56881 atcctcaaag agccgaaaaa cgccctgacc aagcagtatc aggcgctgtt taatctggaa
    56941 ggcgtggatc tggaattccg tgacgaggcg ctggatgcta tcgctaagaa agcgatggcg
    57001 cgtaaaaccg gtgcccgtgg cctgcgttcc atcgtagaag ccgcactgct cgataccatg
    57061 tacgatctgc cgtccatgga agatgtcgaa aaagtggtta tcgacgagtc ggtaattgat
    57121 ggtcaaagca aaccgttgct gatttatggt aagccggaag cgcaacaggc atctggtgaa
    57181 taattaacca ttcccataca attagttaac cgaaaagggg ggattttatc tcccctttaa
    57241 tttttcctct attctcggcg ttgaatgtgg gggaaacatc cccatatact gacgtacatg
    57301 ttaatagatg gcgtgaagca cagtcgtgtc atctgattac ctggcggaaa ttaaactaag
    57361 agagagctct atgaatcctg agcgttctga acgcattgaa atccccgtat tgccgctgcg
    57421 cgatgtggtg gtttatccgc acatggtcat ccccttattt gtcgggcggg aaaaatccat
    57481 ccgttgtctg gaagcggcga tggaccatga taaaaaaatt atgctggtcg cgcagaaaga
    57541 agcttcaacg gatgagccgg gtgtaaacga tcttttcacc gtcgggaccg tggcctctat
    57601 attgcagatg ctgaaactgc ctgacggcac cgtcaaagtg ctggtcgagg ggttacagcg
    57661 cgcgcgtatt tctgcgctct ctgacaatgg cgaacacttt tctgcgaagg cggagtatct
    57721 ggagtcgccg accattgatg agcgggaaca ggaagtgctg gtgcgtactg caatcagcca
    57781 gttcgaaggc tacatcaagc taaacaaaaa aatcccacca gaagtgctga cgtcgctgaa
    57841 tagcatcgac gatccggcgc gtctggcgga taccattgct gcacatatgc cgctgaaact
    57901 ggctgacaaa cagtccgttc tggagatgtc cgacgttaac gaacgtctgg aatatctgat
    57961 ggcaatgatg gaatcggaaa tcgatctgct gcaggttgag aaacgcattc gcaaccgcgt
    58021 taaaaagcag atggagaaat cccagcgtga gtactatctg aacgagcaaa tgaaagctat
    58081 tcagaaagaa ctcggtgaaa tggacgacgc gccggacgaa aacgaagccc tgaagcgcaa
    58141 aatcgacgcg gcgaagatgc cgaaagaggc aaaagagaaa gcggaagcag agctgcagaa
    58201 gctgaaaatg atgtctccga tgtcggcaga agcgaccgta gtgcgtggat atatcgactg
    58261 gatggtacag gtgccgtgga atgcgcgtag caaggtcaaa aaagacctgc gtcaggcgca
    58321 ggaaatcctt gataccgacc attatggtct ggagcgcgtg aaagatcgta tccttgagta
    58381 tcttgcggtt caaagccgtg tcaacaaaat caagggtccg atcctctgcc tggtagggcc
    58441 gccgggggta ggtaaaacgt ccctgggtca gtccatcgcc aaagccaccg ggcgtaaata
    58501 tgtccgtatg gcgctgggcg gcgtgcgtga tgaagcggaa atccgtggtc accgccgtac
    58561 ttacatcggt tctatgccgg gtaaactgat ccagaaaatg gcgaaagtgg gcgtgaaaaa
    58621 cccgctgttc ctgctcgatg agatcgacaa aatgtcttct gacatgcgtg gtgatccggc
    58681 ctccgcactg cttgaagtgc tggatccaga gcagaacgta gcgttcagcg accactacct
    58741 ggaagtggat tacgatctca gcgacgtaat gtttgtcgct acgtcgaact ccatgaacat
    58801 tccggcaccg ttgctggatc gtatggaagt gattcgcctc tccggttata ccgaagatga
    58861 aaaactgaac atcgccaaac gtcacctgct gccgaagcag attgaacgta atgcattgaa
    58921 aaaaggtgag ctgaccgtcg acgatagcgc cattatcggc attattcgtt actacacccg
    58981 tgaggcgggc gtgcgtggtc tggagcgtga aatctccaaa ctgtgtcgca aagcggttaa
    59041 gcagttactg ctcgataagt cattaaaaca tatcgaaatt aacggtgata acctgcatga
    59101 ctacctcggt gttcagcgtt tcgactatgg gcgcgcggat aacgaaaacc gtgtcggcca
    59161 ggtaaccggt ctggcgtgga cggaagtggg cggtgacttg ctgaccattg aaaccgcgtg
    59221 cgttccgggg aaaggcaaac tgacctatac cggttcgctc ggcgaagtga tgcaggagtc
    59281 tattcaggcg gcgttaacgg tggttcgtgc gcgtgcggaa aaactgggga tcaaccctga
    59341 tttttacgaa aaacgtgaca tccacgtcca cgtaccggaa ggtgcgacgc cgaaagatgg
    59401 tccgagtgcc ggtattgcca tgtgcaccgc gctggtttct tgcctgaccg gtaacccggt
    59461 tcgtgccgat gtggcaatga ccggtgagat cactctgcgt ggtcaggtac tgccgatcgg
    59521 tggtttgaaa gaaaaactac tggcagcgca tcgcggcggg attaaaacag tgttaattcc
    59581 gttcgaaaat aaacgcgatc tggaagagat tcctgacaac gtaattgccg atctggacat
    59641 tcatcctgtg aagcgcattg aggaagttct gactctggcg ctacaaaatg aaccgtctgg
    59701 catgcaggtt gtgactgcaa aatagtgacc tcgcgcaaaa tgcactaata aaaacagggc
    59761 tggcaggcta attcgggctt gccagccttt ttttgtctcg ctaagttaga tggcggatcg
    59821 ggcttgccct tattaagggg tgttgtaagg ggatggctgg cctgatataa ctgctgcgcg
    59881 ttcgtacctt gaaggattca agtgcgatat aaattataaa gaggaagaga agagtgaata
    59941 aatctcaatt gatcgacaag attgctgcag gggctgatat ctctaaagct gcggctggcc
    60001 gtgcgttaga tgctattatt gcttccgtaa ctgaatctct gaaagaaggg gatgatgtag
    60061 cactggtagg ttttggtact tttgccgtta aggaacgtgc tgcccgtact ggccgcaacc
    60121 cgcagaccgg taaagagatc accatcgctg ctgctaaagt accgagcttc cgtgcaggta
    60181 aagcactgaa agacgcggta aactaagcgt tgtccccagt ggggatgtga cgaagttcaa
    60241 gggcgcatct actgatgtgc cttttttatt tgtattcggt gactttctgc gtcttgtggg
    60301 ctgacaattg cccccgtttc ttgtcacaat aggcctttgc gcgcatcgat acgttgcgtg
    60361 aggtacacag tcatctacag cggagtgttg ttacaccatg atggacagct tacgcacggc
    60421 tgcaaacagt ctcgtgctca agattatttt cggtatcatt atcgtgtcgt tcatattgac
    60481 cggcgtgagt ggttacctga ttggcggagg caataactac gccgcaaaag tgaatgacca
    60541 ggaaatcagc cgtgggcaat tcgagaacgc cttcaacagc gagcgtaatc gcatgcagca
    60601 acagctgggc gatcaatact ccgagctggc agcgaacgaa ggctatatga aaaccctgcg
    60661 tcaacaggtg ctgaatcgtc tgatcgacga ggcgcttctg gatcagtacg ctcgtgagct
    60721 gaaactgggt atcagcgatg agcaggttaa acaggcgatt ttcgcgaccc cagccttcca
    60781 ggttgacggc aaatttgata acagccgcta taacggtatc ctcaaccaga tggggatgac
    60841 cgccgatcag tacgcccagg cgctgcgtaa ccagctcact acccaacagc tgattaacgg
    60901 cgttgccggt accgatttta tgctgaaagg tgaaaccgac gagctggcgg cactggtagc
    60961 tcaacaacgc gtggtgcgtg aagcggctat cgatgttaac gcgctggcgg cgaagcagcc
    61021 tgtgaccgaa caggaaattg ccagctacta cgaacaaaac aaaaacaatt tcatgacgcc
    61081 ggaacaattc cgcgtgagtt acatcaagct ggatgccgcg acgatgcagc aaccggttag
    61141 cgatgcggat atccagagct actacgatca gcatcaggat caattcaccc agccgcagcg
    61201 tacccgttac agcatcatcc agaccaaaac tgaagatgaa gcgaaagcgg tacttgatga
    61261 gctgaataag ggcggtgatt ttgctgcatt agccaaagaa aaatctgccg atattatctc
    61321 tgcccgtaac ggcggtgata tgggttggtt agaagatgcc actatcccgg acgaactgaa
    61381 aaatgcgggt ctgaaagaaa aaggccaact gtctggtgtt atcaaatctt cggtcggttt
    61441 cctgattgta cgtctggacg acattcagcc agcgaaagtg aaatcgttag acgaagtacg
    61501 tgacgacatt gcggcgaaag tgaaacacga aaaagccctc gatgcgtact acgcgctgca
    61561 gcagaaagtg agcgatgcgg caagcaacga caccgagtct ctggccggtg cagagcaagc
    61621 tgccggcgtt aaagccactc agacgggttg gttcagcaaa gataacctgc cggaagagtt
    61681 gaacttcaag ccagttgccg acgctatctt caacggcggt ctggtaggtg aaaacggcgc
    61741 gccgggcatc aactctgaca tcatcaccgt agacggcgac cgcgcattcg tgctgcgcat
    61801 cagcgagcac aaaccggaag cggtgaaacc gttggcagat gttcaggaac aagttaaggc
    61861 actggttcag cacaacaaag ctgaacaaca ggcgaaagtg gatgctgaga aactgctggt
    61921 tgatttgaaa gccggcaaag gtgcggaagc gatgcaggct gccggtctga aatttggcga
    61981 gccgaaaacc ttaagccgtt ccggtcgtga cccgattagc caggctgcgt ttgcactgcc
    62041 gctgccagcg aaagacaaac cgagctacgg tatggcgacc gatatgcaag gtaatgtggt
    62101 tctgctggcg ctggatgaag tgaaacaagg ttcaatgccg gaagatcaga aaaaagcgat
    62161 ggtgcagggt atcacccaga acaacgcaca aatcgtcttt gaagctctga tgagtaacct
    62221 gcgtaaagag gcgaaaatca aaattggcga tgcgctggaa cagcaataat cctgaagccg
    62281 cctcgcaaaa aaatgctttg cagctgtaac aagaaaaggt cgctttcgcg gccttttcca
    62341 tttctgaaca ttgccatttg tttactgttt tcactgccgt taaggtgatt ccactgttaa
    62401 caaacaagga gaaaacagta tgaaacacgg aattaaagca ctgctcatta ccctgtccct
    62461 ggcctgtgcc ggaatgtctc atagtgctct ggcggcagct cctgcggcaa aaccgacaac
    62521 ggtagaaacc aaagcggaag ctcctgcagc acaaagtaaa gcagcagtac cggcgaaagc
    62581 cagtgacgaa gaaggcaccc gggtcagcat taataatgcc agcgcggaag agttagcccg
    62641 cgcgatgaat ggcgttggcc tgaagaaagc gcaggcgatt gtcagttatc gcgaagagta
    62701 cggtccgttt aaaacggtgg aggatctaaa gcaggtgccg gggatgggca attcgctggt
    62761 ggaacgtaat atggcggtat taaccctgta attaatttgc atagtggcaa ttttttgcca
    62821 gactgaagag gtcataccag ttatgacctc tgtacttata acagttctta taacagttct
    62881 tataacaaca acgtaaggtt attgcgctat gcaaacacaa atcaaagttc gtggatatca
    62941 tctcgacgtt taccagcacg taaacaacgc ccgctacctt gaatttctcg aagaagcccg
    63001 ctggcatggg ttggaaaata gcgacagttt tcactggatg acggcccata acatcgcttt
    63061 cgtcgtggtc aatatcaata ttaactatcg ccgcccggcg gtattaagcg acctgttaac
    63121 cattaccagt cagttgcagc aattaaacgg taaaagtggc atcttaagcc aggtcattac
    63181 actggagccg gaaggacagg tggtagcgga tgcgcttatt acgtttgttt gtattgatct
    63241 taaaacgcag aaagcattag ctctggaagg ggaattgcgc gaaaagctgg agcagatggt
    63301 taagtaaacg ttttgtggtg ccggatgctc aagccgcatc cggcgacacc cggaataatt
    63361 acttcaaccc ggttttctgc ttcatcgctg ccatcaccgt cggtttatcg gccagataat
    63421 gattcaaacc gttggcacgt aaattacacg ccgcacaatg accgcaaccg tcgcctttaa
    63481 tgccgttata acaggtcagc gtttcgttac ggactaaatc cagcttgccg taataatctg
    63541 ccagcgccca ggtttccgct ttatcaatcc acatcagcgg cgtttcaaaa cgaatatctt
    63601 tcgccatgcc caaactgacg gcatggttta gtgctttcac aaactcatcg cgacaatccg
    63661 ggtagccgga gaaatccgtt tcgcagacgc cggtaattac ggcttctgct tttacctgat
    63721 acgcatatat tgccgccagc gtcaggaaca aaatattacg ccctgggaca aacgtattcg
    63781 ggataccatc ggcttcaggt tcataatcag gcaccggaat gctgtcacgc gtcaggctgc
    63841 tgaccgccag ctcgttgagc agcgttacat caagaacctt atgcgcgcgt gcccccagtt
    63901 tcagcgccag ttcgcgtgcc acgtcgattt ctgcgcgatg gcgttgaccg taatcgaacg
    63961 tcacgcaatg gacttcatca tattgttgta atgcctgcac cagacaggtg gtggaatcct
    64021 ggcctccact gaacacaacg acagcacgtt tcatagataa tcctgcttga acaataaaag
    64081 cgttatggta acgcctgcga ttaacccgga ccagctattc attgcgacgg cgcgggaagc
    64141 caggcttcgg taaattcaaa ccagccgcgc ggtgtcagtc gcacaccgtt cacgccggga
    64201 ggggcgctaa tgcgatagtg atagttgaac agcggcgtca gcgtcgcatc tgccattaac
    64261 tggctaaaaa ccgctttcag ggcattaaat cggttttcct catcaggcat tacttgcact
    64321 gcgtccagtg tcgattgcaa atgtgcatat gctggagcgt cgaaaacatg tggccacagt
    64381 ggatcgcaac gcagccattg ctccagggta tattccggtg cttcgccaat taatctgtcg
    64441 cccatcatga ggtctgcgtg tgccagtagg gtcgtgtcgt cccagttttt tgcgttatga
    64501 aaaataattg tgagttcaca gccttccgct gccagtgtcg cctgtaggcg ttctgccatg
    64561 gtatgaagtt ctatcggtag gtgataaacc agcgtcaagg ttttcggtag tttaacttca
    64621 tccggtacct gccaatgcgg aatagtccag ccaggcagta atgcatgact ggcggtgatc
    64681 aggttttctc cgacttctaa cgtttgtaat aaaccggatt gatgaataat ggagattact
    64741 tttcgcgcct gccagaggga cagtcggaga cttttgcgca atgttaaata gcaaaaacct
    64801 aaactgatgc cgctactgac ctggctgacc cgttgcagct cctccggttt gccaatggtg
    64861 atttgcacgg gatgccgaca actggttccc aaatcttttt cgaaaagcgg cggagttatc
    64921 cagtactcaa ccgctttaag cagcggatga cgtaaatggt aataatcatg gctctccagg
    64981 cgcaccagtt ccgctgtgaa ttgtgttaag cgaaaaggac ctgtgccgat cagtgggaat
    65041 tgcggatgcg ccagatggct gcaatagctc gccagtcggt gcgcaagcca gtaatcgggg
    65101 cgatgtaaaa agaaggtcag acactgcgga tgggtgactt caatacgctt cacgctaata
    65161 aataattgat ccagtgctgg cagttgtaac agcatcaata atcgctggtg taagtgtgag
    65221 gcttttactg catcgccgtt atgccagtgt agcgttgaac gaagataaaa gtcccagcgt
    65281 aacccgtcag tagaggtttc ccagtgatgt gctaaatcgc caatcgggcg ctgagtatta
    65341 ttatcgaagc gggtcaggcc ggaaaatatc tgcccggcca gatgctgctc ggcacggccg
    65401 ggcaaaaagc ccggttgtag cggttcgagc gggcgatagt agggaatacg caacgtgggc
    65461 gtatcgtttt gccattgtcc gcccataaac ggctgtaaca gagtgcgcag ctcacctggg
    65521 gccagttgcg ccagctccag cacatcttgc tgctttccgg tttccagcgc ctgttccatc
    65581 atcgcattgc gtagcgattc tggcgtgacc agaaagcgta gttgaccgcg ctttccgcgt
    65641 cctgactgcg cctgccactc cagccatccc gcctcctgtg cctgacgcaa caccgtacga
    65701 acatggcgtt cgctgcaaaa acagcgttcg gccagttcgc tgacggtgac ggtttgcggc
    65761 tttccggcgg aaggttgcca cagacgttga tactggttaa gacggttgag cagtcgcata
    65821 taaacccgga acaatattat ttaactattc actattactt ccgtatatat caggtgatac
    65881 tcaatcacca ttaactgtgt cacagagtgg agaaagaaat ggctcgtctg gcagcatttg
    65941 atatggatgg cactttattg atgcctgacc atcatttagg tgagaaaacc ctctctactt
    66001 tggcgcggct gcgtgaacgc gacattaccc tcacttttgc cacggggcgt catgcgctgg
    66061 agatgcagca tattctcggg gcgctatcgc tggatgcata tttgattact ggcaacggaa
    66121 cgcgcgtgca ttctctggaa ggtgaacttt tacatcgtga tgatttacct gcggatgtcg
    66181 cggagctggt gctgtatcag caatgggata cccgagcaag catgcatatc ttcaatgacg
    66241 atggttggtt taccgggaaa gagatccctg cgttgttgca ggcatttgtc tatagcggtt
    66301 ttcgttatca gataatcgat gtcaaaaaaa tgccactcgg cagcgtcacc aagatctgct
    66361 tctgtggcga tcacgacgat cttacacgct tgcagatcca gctatacgaa gcattaggcg
    66421 agcgtgcaca tttatgtttt tccgccacgg attgcctcga agtgctgccg gtgggctgca
    66481 ataaaggcgc tgcattgacg gtgctgaccc aacatttagg tttatcgtta cgcgattgta
    66541 tggcctttgg tgatgcgatg aacgatcgcg aaatgttagg cagcgtcggt agcggattta
    66601 ttatgggcaa tgcgatgccg caactgcgcg cggagctccc gcatttaccg gtgattggac
    66661 attgccgaaa tcaggctgtc tctcactatt tgacgcactg gctggactat ccacatctac
    66721 cttattcccc cgaataacga gatcccttcc agcaccgggc aattgcccgg ttttttttgc
    66781 gttgaatttg tcattttgtg ccgtggtgct taaaccgcac agaataaatt gtcgcgattt
    66841 cacctttaaa atagaattaa aagagaaaaa aattctctgt ggaagggcta tgttagataa
    66901 aattgaccgt aagctgctgg ccttgctaca gcaggattgc accctctctt tgcaggcact
    66961 ggctgaagcc gttaatctga caaccacccc ctgctggaag cgtctgaaac ggctggagga
    67021 cgacggtatt cttatcggca aagtcgccct gctggatccg gaaaaaatag gcctcggcct
    67081 gaccgccttt gtgctgataa aaacgcaaca tcacagcagc gaatggtatt gccgctttgt
    67141 cacggtggtt accgaaatgc cagaagtgct ggggttctgg cgcatggctg gtgaatacga
    67201 ttatctgatg cgcgtccagg ttgccgacat gaaacgctac gacgagtttt ataagcgtct
    67261 ggtaaacagt gtaccggggc tgtcggacgt cacttccagc ttcgcgatgg aacagattaa
    67321 atacaccact tctttaccca tcgaataaat atccagaatc aagtcaggac acaacgcgtg
    67381 cgattatttg ctcaattaag ctggtatttc cgtcgggaat ggcgtcgcta tctcggggct
    67441 gtcgccttgc ttgtcattat cgcgatgctg caactggttc cgccaaaagt ggttggtatt
    67501 gttgttgatg gcgtgacaga acaacacttt actaccgggc agatcctgat gtggatcgcc
    67561 accatggtgc tgattgccgt tgtggtttat ctcctgcgtt acgtctggcg cgtattgctg
    67621 tttggtgcgt cttatcaact ggctgttgaa ctgcgtgaag attattaccg ccagctaagc
    67681 cggcagcatc ctgagtttta cctgcgtcat cgcacgggcg accttatggc ccgtgcgaca
    67741 aatgacgtcg atcgcgtcgt gtttgccgcc ggagaagggg tgctgacgct ggtggattca
    67801 ctggtaatgg gctgcgctgt gttgattatg atgtctacgc aaattagctg gcagttgacc
    67861 ttatttgccc tgttgccgat gccagtgatg gcgatcatga tcaagcgcaa cggcgatgcc
    67921 ttgcatgaac gctttaagct ggcacaggcg gcgttttcca gtcttaatga ccgcacccag
    67981 gaaagcctca ccagtatccg catgatcaaa gcctttggtc tggaagatcg tcagtcggcg
    68041 ttatttgccg cggatgccga agataccggc aaaaaaaaca tgcgggtggc gcgtattgat
    68101 gctcgtttcg acccgaccat ctatatcgcg attggtatgg cgaacttgct ggcgatcggc
    68161 ggcggtagtt ggatggtggt gcagggcagt ttaacgctgg gccagctcac cagttttatg
    68221 atgtatttag gtctgatgat ttggccaatg ctggcgctgg catggatgtt taacattgtg
    68281 gaacgtggca gcgcggcgta tagccgaatt cgtaccatgc tggccgaagc gccagtcgtt
    68341 attgatggta gtgataaggt gccagaaggt cgtggtgaac tggatgtgaa tattcgccag
    68401 tttacgtatc cgcagactga ccatcctgcg ctggaaaacg tcaatttcgc cctgaaaccc
    68461 ggtcagatgc tgggtatctg cgggccgact ggttccggca aaagtaccct gttgtcgctc
    68521 attcagcgtc atttcgacgt cagcgagggt gatatccgtt ttcatgatat tcctctgacg
    68581 aagttacaac tcgatagctg gcgtagccgt ctggcggtgg tcagccagac accattcctt
    68641 ttttccgaca ccgtggcgaa caacatcgcg ttgggttgcc cgaatgccac ccagcaagag
    68701 attgaacacg tagcgcggtt agccagcgta catgacgata ttttgcgtct gccgcaaggt
    68761 tacgacacag aagtgggcga gcgcggtgtg atgctttctg gcggacaaaa acagcgtatc
    68821 tccattgctc gagcgttatt agtcaacgcg gaaatcctca tccttgatga tgcgctttca
    68881 gcggtggacg gacgcacaga gcaccagatc ctgcataacc tgcgtcagtg ggggcaggga
    68941 agaacggtaa tcatcagtgc ccatcgcctt tctgcactga cggaagccag tgaaattatt
    69001 gtgatgcagc acgggcatat cgcccagcgt ggcaatcatg atgtgctggt acaacaaagc
    69061 ggctggtatc gcgatatgta tcgctatcaa caactggagg cggcgctcga cgacgccccg
    69121 gaaattcgcg aggaggccgt cgatgcgtag ttttagccaa ctgtggccga ctctcaagcg
    69181 tctgttagcg tacggttcac cgtggcgtaa accgttgggg attgcggtcc tgatgatgtg
    69241 ggttgcggcg gcggcagaag tcagtgggcc gctgcttatc agctatttta tcgacaatat
    69301 ggtagcgaaa aataacctgc cgttgaaagt ggttgcaggg ctggcggcgg cgtatgttgg
    69361 gctgcaactg tttgcagccg ggctacatta cgcgcagtcg ctgctgttta atcgggcggc
    69421 agtaggcgta gtgcaacagt tgcgtaccga cgtgatggat gctgcgttac gccagccatt
    69481 aagcgagttt gatacccaac ccgtcgggca ggtgatttcc cgcgtcacta atgacactga
    69541 agtgatccgc gatctctacg ttaccgtagt ggcaactgtc ctgcgtagcg ccgcactggt
    69601 gggcgcgatg ctggtggcga tgttcagcct cgactggcga atggcgctgg tggcgataat
    69661 gattttcccg gtggtgctgg tggtaatggt gatatatcag cgttacagca cgccgattgt
    69721 ccgtcgtgtg cgcgcttatc tggcggatat caacgacggc tttaacgaaa tcatcaatgg
    69781 catgagcgtt atccagcagt tccgtcagca ggcgcgattt ggcgaacgta tgggtgaggc
    69841 cagtcgttca cactatatgg cgaggatgca aaccctgcgc ctcgacggtt ttctgctgcg
    69901 tccgctgctg agtctgtttt catcgctcat tctttgtggc ttgttgatgc tgtttggctt
    69961 ctccgccagc ggcaccattg aagtgggcgt gttgtatgcg ttcatcagtt atttggggcg
    70021 acttaacgaa cccttaatcg aactgaccac gcagcaggcg atgctgcaac aggctgttgt
    70081 tgctggtgag cgcgtttttg agctgatgga cggaccgcgc cagcaatatg gcaatgatga
    70141 tcgctcgttg cagagcggca ccatcgacgt cgataacgtg tcatttgctt atcgcgatga
    70201 caatctggtg ctaaagaaca ttaatctctc tgtgccttcg cgcaactttg tggcgctggt
    70261 cgggcatacc ggcagtggca aaagcaccct cgccagttta ttgatgggct attacccgct
    70321 aacggaaggt gagattcgcc ttgatggtcg tccattaagt acgctaagtc acagcgcgct
    70381 gcgccagggc gtggcaatgg tgcagcaaga tccggtggtg ctggcggata ccttcctcgc
    70441 caacgtgacg ctgggacgtg atatctctga agaacgcgtc tggcaggcgc tggaaaccgt
    70501 gcagctggcg gagctggcgc gtagcatgag tgatggtatt tacacgctgc ttggcgagca
    70561 ggggaataat ctctcagtcg ggcaaaagca actgctggca ctggcgcgcg tgctggtgga
    70621 gacgccgcaa atcctgatcc ttgatgaggc aaccgccagc attgactccg ggactgaaca
    70681 ggcgattcaa catgctctgg cggcggtgcg tgaacatact acgcttgtgg tgattgctca
    70741 ccgcttatcg actattgttg atgccgacac cattctggtg cttcatcgtg ggcaagccgt
    70801 ggagcagggc actcaccagc aactgctggc ggcccaggga cgatactggc agatgtatca
    70861 actgcaactt gcgggcgaag agctggcagc cagcgtgcgt gaagaggaat cattgagcgc
    70921 ctgaatagcg caatatttca tcgttggtgc aaaaatgtaa cgcactgtgc actgtcatag
    70981 tgcgttttca ttttcaatct tcttaacttc ctgctctctt tctcgttttt catttctggc
    71041 acaccgcttg caataccttc ttcgtgtagc agaaccatta ccgaattctg accggagggg
    71101 atctatgaag ctggtgaccg tgataatcaa accattcaag ctggaagacg ttcgtgaagc
    71161 gttatcttcc attggtattc agggcctgac cgtcaccgaa gtgaaaggtt ttgggcgtca
    71221 gaaagggcat gccgagctgt accggggggc ggaatacagc gtcaacttcc tgccaaaagt
    71281 aaaaattgat gtggcgattg ctgatgacca actcgatgaa gtgatcgata tcgtcagcaa
    71341 agcggcttac accggaaaaa ttggcgacgg caaaatcttc gtcgctgaat tgcaacgcgt
    71401 cattcgtatt cgtaccggcg aagccgacga agcggcgctg taatctctgg cacacagcaa
    71461 caggaacgaa aaatgaagat agcaacgata aaaactgggc ttacttcact ggcgatgctg
    71521 ccgggactgg taatggctgc acctgcggtg gccgataaag ccgacaatgc atttatgatg
    71581 atttgtactg cgctggtgct gtttatgact attccgggga ttgccctgtt ttatggaggg
    71641 ctgattcgtg gcaaaaacgt gctgtcgatg ctgacgcagg tgaccgtgac gtttgcactg
    71701 gtctgtattc tctgggtggt ttacggctac tcgctggcgt ttggcgaagg caacaacttc
    71761 ttcggcaaca ttaacgggtt gatgctgaaa aacattgaac tgacggcggt gatgggcagc
    71821 atttatcagt atatccacgt ggcgtttcag ggatcgtttg cctgcattac cgtaggcttg
    71881 atagttgggg cgctggcgga acgaatccgc ttctcagctg tgttgatttt tgtggtggta
    71941 tggctgacgc tctcttacat tccgattgcg catatggtct ggggcggcgg tttgctggct
    72001 tctcacggtg cgctggattt cgcgggtggc acggtagtgc acattaacgc cgcaatcgcc
    72061 ggtctggtgg gcgcgtatct gataggcaaa cgcgtgggct tcggcaaaga ggcgtttaaa
    72121 ccgcacaacc tgccgatggt cttcaccggg actgccattc tctatatcgg ttggtttggc
    72181 tttaacgccg ggtcagcggg cacggcgaat gaaatcgcgg cactggcatt tgtgaatact
    72241 gtggtcgcaa ccgcggcggc aattcttggc tggatcttcg gtgaatgggc gctgcgtggt
    72301 aagccttcac tgctgggagc gtgttctggc gcgattgccg gtctggtcgg cgtgacgcca
    72361 gcctgtggtt acattggggt tggcggcgcg ttgattatcg gcgtggtagc tggtctggcg
    72421 ggcttgtggg gcgttaccat gctcaaacgc ttgctgcggg tggatgatcc ctgcgatgtc
    72481 ttcggtgtgc acggcgtttg tggtattgtc ggctgtatca tgaccgggat ttttgccgcc
    72541 agctcgctgg gcggcgtggg cttcgctgaa ggtgtgacga tgggccatca gttgctggta
    72601 cagctggaaa gcatcgccat tacgattgtc tggtctggtg tggtggcatt tatcggctac
    72661 aaactggcgg atctgacggt tggtctgcgt gtaccggaag agcaggagcg agaagggctg
    72721 gacgtcaaca gccacggcga gaatgcctat aacgcgtaac aagcactgca aaaaacagcc
    72781 ggacggtttt cacctccggc tattttttta attgtgatta cgcatcaccc cttcctgaac
    72841 ggtcgaggca accagcacgc cgtcctgggt ataaaactca ccgcgcacaa agccgcgtgc
    72901 gctggacgcc gaggtgcttt ccacgctata cagcagccat tcattcaaat taaacgggcg
    72961 atggaaccac atggaatggt caatggtggc aatctgaatc cccggttcga gaaaaccgat
    73021 gccgtgcggc tgtagagcta ccggcaggaa attaagatca gaagcataac cgagcagata
    73081 ctgatgaacg cgcagatcat ccggcacgct accatttgcg cggatccaca cctgacgatg
    73141 cggttctgcg acgtgacctt tcagtgggtt atgaaactcc accggacgga cttccagcgg
    73201 acgatcgcag atgaatttat ctttcagcac tggcggcagc aggtgcgcca gcgattgggc
    73261 gatttgcgtt tctgaaggca ggccatcagg cgctggtgcg gacggcattg ttttttgatg
    73321 ttcgaaaccc gcttctggtg cctggaaaga ggcagtcata taaaaaatcg gtttgccgtt
    73381 ttgaatagca gcaacccggc gggcgctgaa gctgttaccg tcacgcagtg tttcgacatc
    73441 ataaataatc ggcttcttac tatcgccagg gcgaagaaag tagctgtgaa aagaatgtac
    73501 cagccgctcg tcagggacgg tctcttttgc agcatacaag gcctgaccca cgacctggcc
    73561 gccaaatacc tggcgtaaac ctaaatcttc actctggccg cgaaagagtc cttcctcaat
    73621 tttttccaga tttaacaatg tcagtaaatt ttttagcgcc tgactcatat aactctccag
    73681 taacaaagct gccgcagcaa gccaaagtga gttgagtata acgcaaattt gccactggtc
    73741 cgatgggtgc aatggtctga attacgggct aattacaggc agaaatgcgt gatgtgtgcc
    73801 acacttgttg acgttactat tttgttaacc actcttccgg cgaggaaagt tagcccgctg
    73861 gtgcattgat aataaggaga agtgaatgaa actcgtgcac atggccagtg gtttagcggt
    73921 tgcgattgcg ttggcggctt gcgcagataa aagcgcggat attcagacgc cagcaccggc
    73981 tgcaaatacg tctatttcag caacacaaca acctgctatc cagcaaccga atgtctccgg
    74041 taccgtttgg atccgtcaga aagtcgcact gccgcctgat gccgtgctga ccgtgacact
    74101 ttctgacgcg tcgttagccg atgcgccgtc gaaagtgctg gcgcagaaag cggtgcgtac
    74161 cgaaggtaaa cagtcaccat tcagctttgt tctgccattt aacccggcag atgttcagcc
    74221 gaacgcgcgt attctgttga gtgcggcgat taccgtgaat gacaaactgg tatttattac
    74281 cgataccgtt cagccggtga tcaaccaggg cggaactaaa gccgacctga cattggtgcc
    74341 ggtgcagcaa accgccgtgc cggttcaggc tagcggtggc gcaacgacta ccgtaccttc
    74401 aacttcacca acccaggtga atccgtcttc ggcagttcca gctccaacgc aatattaagc
    74461 gaagttaacc ctctccgccc ggagagggtt agtagttcca gcgataaagc tgcaagtcga
    74521 tttgcccgct tcccgacacc atcacacctt ctgccagtaa tgcctgtcgc tgacgctgta
    74581 aatccggtcc ggtcagtgaa atggtgccgt ggcgattaac cacccggtgc cagggcaagg
    74641 tgctgccttc ggggagacgc tttaacacac cgccaacctg gcgcgcggca cggggcgagc
    74701 ccgccagttt cgccacatca ccgtaagtgg tgacatagcc ttcgggaata gcggctacga
    74761 tttgccagac gcgttgggga aatgaatctt ctttttccat cttttcttcc tgaggtaatt
    74821 tttcagcata atctggaaaa acgcccgagt gaagccgcat tgcgcaagaa accagcatct
    74881 ggcacgcaat gggttgcaat tagccggggc agcagtgata atgcgcctgc gcgttggttc
    74941 tcaacgctct caatgggggc tctgttggtt ctcccgcaac gctactctgt ttaccaggtc
    75001 aggtccggaa ggaagcagcc aaggcagatg acgcgtgtgc cgggatgtag ctggcagggc
    75061 ccccacccat ttctgcctcc taccatttcg tcaaaaaatc ccaacatggc taaactttaa
    75121 ccacaactga cgtcgcaaga attgtctggc tgcgcagtac gcttcggagg tatgtctgat
    75181 gaagtatgtt gatggttttg ttgttgccgt tcctgccgat aaaaaggatg cctatcggga
    75241 aatggccgct aaggccgcgc cattatttaa agagttcggg gcgcttcgta ttgtcgaatg
    75301 ctgggccagc gatataccgg atggtaaagt gaccgatttt cgtatggcgg tgaaagcgga
    75361 agagaatgaa gaggttgtct ttagctggat tgaataccct tcaaaagagg tccgcgacgc
    75421 tgctaatcaa aagatgatgt cggacccacg gatgaaagag ttcggcgagt ccatgccgtt
    75481 tgatggtaag cgaatgatct atggcggatt cgagtcaatc atcgacgagt aggtagcgtg
    75541 acgggctgtg cggcgtgccg tcagccctat aattcacaaa tgttgctcgg cccagcgtaa
    75601 gaaatcctct ttcggtaatg ccttgctgta gagccagccc tgaccgtagt gcacgccatg
    75661 ctggcgtagc cactcttctt gtttactggt ttcgattccc tccgcaacca ttttcagttt
    75721 cagtgttttt gccatttcga tgatatgtgg cgtgacattc ttatattcca gcgcatcaac
    75781 gaaagattta tcgatcttca gaatgtcgac atccagatcc tgtaaatagc ttaaacttga
    75841 ataccctgta ccaaaatcat cgagataaat ttcatggccc gcctcccggt agcgagaaat
    75901 tatcggggcg ctggttttcg gatcggcaaa ctcgcgttca gtgagttcaa gcgcgatctg
    75961 tctgggatta acctgatagt gattgatcat ttcacgcagc aattgcggga ttttttccga
    76021 ggtgagcacg gtggattcaa gattgatcga aatatgctgc tgaggatgct gacgcagcca
    76081 gtcgcccata tcttcaaaga cgcttcttat aatcagtagc gtcaatggct cagaaaggcc
    76141 cgtttgctgt gccagcggaa taaaactatc tggtgacaac caactaccgt ctgtctgcgg
    76201 ccagcgcgcc agtgcctcag caccgacaat tttgccattg gctaaggaga caatcggctg
    76261 atagtgcacg caaatatcac gattttcgat agcatcctgc agccgatgat gcggtgactg
    76321 gatacggcgc aaaatacgca gcacaaacat cgctgccagc aggccaatca ccaacccgag
    76381 cggtaaccaa ataaagactt gccgatacca gcctttctgc aacattttcg ttgaagccca
    76441 ggtgatgatc gaaatattca tctccggtaa gggcaggata tcgtaaatga ttccattatt
    76501 ttcgatatgc tcaccgggtg ttttttgtag cctggtaata attccctgag caagttcatc
    76561 gctgctggtt atgacaacgt tatgggcatt gccaataatg gcggcatcaa tttgccatga
    76621 gctataggga atgacatcaa taaaggaagc ggggtcgatc atgacgacat aatgtgccgt
    76681 tcccatggcg accatgtaac ggataatgcc taaatcgtta tgcgatgtta accagacacg
    76741 ataaccatct ttcgaaattt tacctggctc ggggaaggta tcgggcgggc tttcatgctc
    76801 cagagacgaa cattggggaa cgttgttatc gatataaacc acttcctgaa tatagcgata
    76861 actgtaagat acccgacgca tttccatgag atgggcttcg ctacaggcag cgccttgcca
    76921 tctttccagc tcttgcagcg catctttccc ttgtgtcgcc accttattgg cccgaatagc
    76981 gacgcgggag gaatacgtat tcagctcttc aataaatgac gtttctacct gctgatgggc
    77041 cagccagatg cttaagccga caggcagcaa tactgaaaga atcagtactc ccgaaataag
    77101 gccgaccaga tgtcgtgttc tcaccagcat atccttatta acacagtgta gggaaagtat
    77161 atctgattgt ggaaaaaggc tggcaggaga taaggaggta gagctggtat ttcatgaagt
    77221 gatgggtgga agcaatcgtt gtcatttgac caggcgtaga gctttacgcc tggtatgtac
    77281 ccctaactta agatgttgat tcggctcgag cgagggtaaa aatatcgtaa aaagatagtt
    77341 cacctttacg gacgatcatt ttttgcagtt gttctttatg aacatccgcg acacgtggag
    77401 agttcaggat ggcttcaacc agcgcggcag gtacaaagcg cgtgttgtac cattcgccgt
    77461 tatagcaaac gcggaaatcc agcacgtcga tatcttcata gcggtagcgt gggtagacat
    77521 cgaaaaagaa gaaaccatta agcaggataa ataatacaac cagtagccag acagagcctg
    77581 aaagcgtttc ggattgcaac atcaccgcca gggtagcaaa aaaagcaacg tacataccga
    77641 taaacagccc cggatgttta cggataaaac tgatactaaa gcggggtttg ttgtcgcgtt
    77701 tttcgcgggt attcagagac tcaatcgttt cggtcagcag gcgttgtatt tcggtcatcg
    77761 tttgccttcg tgatatctgc aactttccag ggaacaccct attttaacgt gggaatagta
    77821 gaggggaagt aacagatttg ccacgatttt gcataacagt tgagaaaagc tggttacaat
    77881 tttttaatga ttctggctgg attaccgccc acgacaacgt tgtccgggac atcttttgtg
    77941 acaactgcac ctgaggctac cacgacgtta tcaccaatgg tcacaccagg gttaatgact
    78001 gcacgtccgc caatccagac gttattaccg atggtgacgg gtttccccag ttcagcaccg
    78061 ctattacgtg ctacagggtc gatgggatgt gttgccgtgt agatatgaac gcctggtgcc
    78121 aacatacagt tatcaccaat gcgaataggg cagacatcaa gcatcacgca atcgaagttg
    78181 gcgaaaaaat tattgccgag aaaaatgtta tagccatagt cacagcgaaa cgttggctca
    78241 atataagcct ctgtcacctg accgaataaa tcagcaagaa tttgctggcg taatgtgtgc
    78301 tcttccgcca gggaatgatt gtatcggtga ataagccgac gagcgcgcag gcgatcgcga
    78361 gataacgcct catctgccga gtgatacaac tcaccagcaa tcatcttttc tttttctgtg
    78421 ctcattactg acttccggtt gctgaaaatg cggcaacaca gtaagacgaa aagtcagtga
    78481 agagaacgtt cccattacat ctgtgtgatg aagatcacat agggtatgcc ttcatggcga
    78541 aaaaaagtat aaaattctta ataaacagcc ggttatagct ccgaaagcga gttatttatt
    78601 agcgaataaa tttccatact gaggaaggga tcttgtcgta cagtttattc atggtcaatt
    78661 cggcgaggcg gtgatctgcg gctgagtaaa ataccgccag ttcattatct gataattcgt
    78721 atttattttt ctcgataaca cgctccagcg tgtcaattgt ctggcaacga cgtaaacgca
    78781 ttaaataatc ggttttcgtt aaaggttttt cggacatact tctacccatg gttgtaataa
    78841 ttctaacaag ataaactcgc aggattctct ttcgtcgcat tgacaaaaca acggaatagt
    78901 cgattacctg acttccgcca tttctgaaga tcctgcatat taataccata actactgaac
    78961 aacataaagg tgtcatccag atattcgtcg atctgctcaa tgagcttatt gtcttcatta
    79021 tacttaattt tgtaattaag tgcgaaggtc gcaatatgct caatcagttc attcaactgg
    79081 aggttgatcg ccgaggttgg gtcgttaacc cagccatgat tgctttcttc aaggtttgca
    79141 aggcagtcat gatacagggt ttcacagaga aacttaagct gtgcgatatc atgtcttttg
    79201 ggtgagtatt catccataac gcgtcccctt cttagcggtt gaactaacgg acacctttcg
    79261 ggatggaaaa aacttactga cctggacttg ccctctcgtt tgttagctta actataagcc
    79321 actctttgca ggttttcatc gcattattac gaaaaattac aattaggaag gaagcgggac
    79381 aggactcact ttttcatact agcaccaacc cgcagcaggt aaaagcagtt tgctcgaact
    79441 gttcataaca tttcagaatt atcgccagaa gaaattggtg acactaatac caggattgct
    79501 ctgaatatga cgtaataacc gaggaatgaa taaagaatta ccgcaaataa ttaagaatag
    79561 cctctaaatg gttatggatt attaaatcta ttagcgctac ttaatataaa tt
//
LOCUS       DAPOXO010000009        73431 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPOXO010000009 DAPOXO010000000
VERSION     DAPOXO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 73431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73431
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.009"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(48..2117)
                     /gene="glyS"
                     /locus_tag="ROH59_000826"
     CDS             complement(48..2117)
                     /gene="glyS"
                     /locus_tag="ROH59_000826"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDX4803346.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRV
                     ADISLLQ"
     gene            complement(2127..3038)
                     /gene="glyQ"
                     /locus_tag="ROH59_000827"
     CDS             complement(2127..3038)
                     /gene="glyQ"
                     /locus_tag="ROH59_000827"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDX4803347.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            complement(3133..3432)
                     /locus_tag="ROH59_000828"
     CDS             complement(3133..3432)
                     /locus_tag="ROH59_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YsaB family lipoprotein"
                     /protein_id="HDX4803348.1"
                     /translation="MMMNAFFPAMALIVLVGCSTPPPVQKAQRVKVDPLRSLNMEALC
                     KDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR"
     gene            3607..4602
                     /gene="wecH"
                     /locus_tag="ROH59_000829"
     CDS             3607..4602
                     /gene="wecH"
                     /locus_tag="ROH59_000829"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase WecH"
                     /protein_id="HDX4803349.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVINAHSVSPITWDIAN
                     VLNSASRVSVPLFFMISGYLFFGERSAQSRHFLRIGLCLFFYSAIALLYIALFTSINV
                     ELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMVVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLYTRTICGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAVSLLLSMLVQRIDRNRLVS"
     gene            complement(4644..5081)
                     /locus_tag="ROH59_000830"
     CDS             complement(4644..5081)
                     /locus_tag="ROH59_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaB family inner membrane protein"
                     /protein_id="HDX4803350.1"
                     /translation="MDNKISTYSPAFSIVSWVALIGGIVTYLLGLWNAEMQLNEKGYY
                     FAVLVLGLFSAASYQKTVRDKYEGIPTTPIYYMTCLTVFIISVALLLVGLWNATLLLS
                     EKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKETQVTQEEYSE"
     gene            complement(5127..5468)
                     /locus_tag="ROH59_000831"
     CDS             complement(5127..5468)
                     /locus_tag="ROH59_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803351.1"
                     /translation="MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTAT
                     FGNYAYLRAEKLGQLDDFFIHVCQLVALITIGLLFIGVLNAPINAYEMVIYPIAFFVC
                     LFGQMRLFRSA"
     gene            complement(5637..7091)
                     /gene="xylB"
                     /locus_tag="ROH59_000832"
     CDS             complement(5637..7091)
                     /gene="xylB"
                     /locus_tag="ROH59_000832"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDX4803352.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDDMLQACHLSRDQMPALYEGSEITGALLPEVAK
                     AWGMAAVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALITAARQADESAEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            complement(7162..8484)
                     /gene="xylA"
                     /locus_tag="ROH59_000833"
     CDS             complement(7162..8484)
                     /gene="xylA"
                     /locus_tag="ROH59_000833"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDX4803353.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK"
     gene            8850..9842
                     /gene="xylF"
                     /locus_tag="ROH59_000834"
     CDS             8850..9842
                     /gene="xylF"
                     /locus_tag="ROH59_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4803354.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVVKDGFHKESEL"
     gene            9920..11461
                     /gene="xylG"
                     /locus_tag="ROH59_000835"
     CDS             9920..11461
                     /gene="xylG"
                     /locus_tag="ROH59_000835"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HDX4803355.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVSLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALKKFTGSISQLDDAAEQKCILESIQQL
                     KVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            11439..12620
                     /gene="xylH"
                     /locus_tag="ROH59_000836"
     CDS             11439..12620
                     /gene="xylH"
                     /locus_tag="ROH59_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HDX4803356.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            12698..13876
                     /gene="xylR"
                     /locus_tag="ROH59_000837"
     CDS             12698..13876
                     /gene="xylR"
                     /locus_tag="ROH59_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XylR"
                     /protein_id="HDX4803357.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
                     "
     gene            complement(13984..14808)
                     /locus_tag="ROH59_000838"
     CDS             complement(13984..14808)
                     /locus_tag="ROH59_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HDX4803358.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            15128..17158
                     /gene="malS"
                     /locus_tag="ROH59_000839"
     CDS             15128..17158
                     /gene="malS"
                     /locus_tag="ROH59_000839"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDX4803359.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGEYTLQLDTRSGTPT
                     LMISIQNAVEPVASLVRECPKWDGLPLTLDVSATFAEGAAVRDYYSQQIAIVKNGQIT
                     LQPAATSNGLLLLERAETDTSAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGSEADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGDEVKKTLGERWNDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKTDTHAKIIDGFTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALHEWKKANPDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCLAQMDTTWQQMAEKLQDFNVLSYLSSHDT
                     RLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ASVAHWQKISQFRARHPAIGAGKQTTLSLKQGYGFVREHGDDKVLVIWAGQQ"
     gene            17336..18589
                     /gene="avtA"
                     /locus_tag="ROH59_000840"
     CDS             17336..18589
                     /gene="avtA"
                     /locus_tag="ROH59_000840"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HDX4803360.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPEKIEAGVKILAEEIERAWAESH"
     gene            complement(18628..19101)
                     /locus_tag="ROH59_000841"
     CDS             complement(18628..19101)
                     /locus_tag="ROH59_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDX4803361.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHQENQDCAALSPDEFISRI
                     RVIKDHSWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQSRCIGCKSCMLACPFG
                     AMEVVSSRKKARAIKCDLCWHRATGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(19203..20051)
                     /gene="yiaJ"
                     /locus_tag="ROH59_000842"
     CDS             complement(19203..20051)
                     /gene="yiaJ"
                     /locus_tag="ROH59_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HDX4803362.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWESHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DQGAIT"
     gene            20252..21250
                     /gene="yiaK"
                     /locus_tag="ROH59_000843"
     CDS             20252..21250
                     /gene="yiaK"
                     /locus_tag="ROH59_000843"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HDX4803363.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMCGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTEDNSDEYGISQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            21262..21726
                     /locus_tag="ROH59_000844"
     CDS             21262..21726
                     /locus_tag="ROH59_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDX4803364.1"
                     /translation="MIFGHIAQPNPCRLPAAIEKALDFLRTTDFNALDPGVVEIDGKN
                     IYAQIIDLTTREAVENRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRDI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPACNKNATTAIRKIVVKVALAAL"
     gene            21749..22669
                     /locus_tag="ROH59_000845"
     CDS             21749..22669
                     /locus_tag="ROH59_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4862 family protein"
                     /protein_id="HDX4803365.1"
                     /translation="MKTNNAGYIIGAYPCAPSFHQRSEEEEKDFWRQLSETPDILGLE
                     QPCLENFHPLGDQWLLRHTPESWKFVVTAVMETMRRRSENSGFGLASSDEEQRQACVA
                     YYRHLFNKINALQANKVLALALQAAPLATNPNVMQATDAFARSLKEIASWDWPCKLVL
                     EHCDAMTSSSPRKGFLPLENVLEVITDYDISICINWARSAIEGRNTTLPLTHTQMAKQ
                     AGKLGALMFSGTTLNGAYGEWQDLHAPFAPFCAESLMTTDHVRELFNVAESSTLHFAG
                     IKLLEINATADVHHRIEILRNGIHSLNESR"
     gene            22783..23250
                     /gene="yiaM"
                     /locus_tag="ROH59_000846"
     CDS             22783..23250
                     /gene="yiaM"
                     /locus_tag="ROH59_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HDX4803366.1"
                     /translation="MKRILEGILAIIIAILSCIIFINIILRYGFHTSILSIDELSRLL
                     FVWLTFIGAIVAYMDNSHVQVTFLVEKLSPANQQRVSLLTHTLILLLCLGLAWGAIEK
                     TAQDWSNLSPILGVPVGLMYAAAIPTSLIIALLELRHLYRQFTNTPSRNQQGA"
     gene            23253..24530
                     /gene="yiaN"
                     /locus_tag="ROH59_000847"
     CDS             23253..24530
                     /gene="yiaN"
                     /locus_tag="ROH59_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HDX4803367.1"
                     /translation="MTILIFIVSLLGAIAIGVPIAWALLLCGISLMFWMDIFDVQILA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSQRIVDLPMKLVGHRPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRQANYPVNRAAGLIGSGGIIAAIIPPSIPLIIFG
                     VSSGLSISKLFMAGIAPGIMMGVTLMVTWWWQAKRLNLPCQPKASLREVWQSLVSGIW
                     ALFLPIIIIGGFRSGLFTPTEAGAVAAFYALFVSVVVYREMTFSTLYHVLINAAKTTS
                     VVMFLVASAAVSAWLITIAELPMMVSELLQPLVDSPRLLFIVIMLAIMVISTVMDLTP
                     TVLILTPVLMPLVKEAGIDPVYFGIMFIINCSISLITPPVGNVLNVVCGVAKLKFDDA
                     VKGVAPYVMVLFMLLALFIFIPELITAPLKWMS"
     gene            24543..25529
                     /gene="yiaO"
                     /locus_tag="ROH59_000848"
     CDS             24543..25529
                     /gene="yiaO"
                     /locus_tag="ROH59_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HDX4803368.1"
                     /translation="MKLRSVTYALLIAGVATFSTSSLAAQSLRFGYETSQTDSQHIAA
                     KKFNELLQEKTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFTGLSPVIN
                     LLDVPFLFRDTAHAHKTLDGKVGDDLKVSLEGKGLKVLAYWENGWRDVTNSRQPVKTP
                     ADLKGLKIRTNNSPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAK
                     FFEVQKYLSLTHHAYSPLLVVINKAKFDGLTPEFQQALISSAQEAGSYQRKLVAEDQQ
                     KIIDGMKEAGVEVITDLDRKAFSDALGTQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            25533..27029
                     /gene="lyxK"
                     /locus_tag="ROH59_000849"
     CDS             25533..27029
                     /gene="lyxK"
                     /locus_tag="ROH59_000849"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HDX4803369.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQCCTAVIRSLLTHSGVSGEQIVGIGISAQGKGLFLLDKNDKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSRGEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAVLTGLKAGTPVVGGLFDVVSTALCAGLEDEFTLNAVMGTWAVTSGITHGL
                     RDGEAHPYVYGRYVNDGQFIVHEASPTSSGNLEWFTAQWGEISFAEINQAVASLPKAG
                     GALFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTRVYRDFSE
                     AQRDLQHPVRTLLPDMAAHQLYQQKYQRYQHLIAALQGYHARIKEHTL"
     gene            27026..27688
                     /gene="ulaD"
                     /locus_tag="ROH59_000850"
     CDS             27026..27688
                     /gene="ulaD"
                     /locus_tag="ROH59_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDX4803370.1"
                     /translation="MSRPLLQLALDHSSLEAAQRDVTLLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QNCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKEIRVKAFIAGRSLAGAANPAQVAADFHAQIDSIWGGK
                     RA"
     gene            27681..28541
                     /locus_tag="ROH59_000851"
     CDS             27681..28541
                     /locus_tag="ROH59_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDX4803371.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSAAQRASLVTAMLETGVAIPSMCLSAHRRFPFGSRDDAVRQRAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTE
                     HSPGQFRDVPFGEGCVDFVGIFKTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            28535..29230
                     /gene="araD"
                     /locus_tag="ROH59_000852"
     CDS             28535..29230
                     /gene="araD"
                     /locus_tag="ROH59_000852"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDX4803372.1"
                     /translation="MLEQLKADVLAANLALPVHHLVTFTWGNVSAIDETRQWMVIKPS
                     GVEYEVMTADDMVVVEIASGKVVEGSKKPSSDTPTHLALYRRFAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRLMTAEEINGEYEYQTGEVIIKTFEERGLNP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(29262..30077)
                     /locus_tag="ROH59_000853"
     CDS             complement(29262..30077)
                     /locus_tag="ROH59_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4803373.1"
                     /translation="MLELSMTLPIKVQNGGLFISRGVGRHPARRLESWEIIFVEKGRL
                     TIQEDERIFLVDAGESLLLWPNRQHVGVEDFPADLKFYWLHFEVKAPDNDPRWLTHLS
                     VPQQTKVADPQVLVALFRQFLSEQEKHQRTPALEFIVLLILQQLTRDARLDEQADGAG
                     TTLAWKAQKLIRTQYHRPLSTALLARELYCNADYLGRVYRRVFHLTLTEAIHRQRVRE
                     AEKLLISEARSLTEVAALCGFNDVGYFRQIFRKHTGLTPAAWKRRYSKEHINS"
     gene            30303..31703
                     /locus_tag="ROH59_000854"
     CDS             30303..31703
                     /locus_tag="ROH59_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803374.1"
                     /translation="MTSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMN
                     FLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMGVIADRTQSRWGRFRPWQLWIAI
                     PIGIIGILTFTVPDASMGVKIAWAFGTYLLLSVGYTAINVPYCALINTMTTRHNEVIS
                     CQSWRFVLCGVAGFLVSVGLPWMVDLFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWV
                     RERVPLSTMGKFTLREHLAGLRNNDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQG
                     STGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLAALAVLMWFLPSSPA
                     YQTLWLVVILGNGVILGFTLPLHFSLMAFADDYGEWKTRVRSSGMNFAFNLFFIKLAW
                     ASSAGIISLLFIFVAYQPGVENQTASSLGGIAAMETLLPALFHLLLAMAIRFCKLNNP
                     MMSRIASDLRQRHVQP"
     gene            31714..33687
                     /locus_tag="ROH59_000855"
     CDS             31714..33687
                     /locus_tag="ROH59_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001026880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
                     /protein_id="HDX4803375.1"
                     /translation="MNISEVDLHKLTVSDPFLGQYQQLVRDVVIPYQWDALNDRIPEA
                     EPSHAIENFRIAAGLQEGEFYGMVFQDSDVAKWLEAVAWSLCQKPDAELEKTADEVIE
                     LIASAQCEDGYLNTYFTVKAPEERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLE
                     VVCRLTDHIDSVFGPDESKLHGYPGHPEIELALMRLYEVTEEPRYLALTNYFVEQRGA
                     QPHYYDQEYEKRGQTSHWHTYGPAWMVKDKAYSQAHLPIAQQQTAIGHAVRFVYLMTG
                     VAHLARLSHDESKRQDCLRLWNNMAQRQLYITGGIGSQSSGEAFSSDYDLPNDTVYAE
                     SCASIGLMMFARRMLEMEGDSQYADVMERALYNTVLGGMALDGKHFFYVNPLEVHPKS
                     LKFNHIYDHVKPIRQRWFGCACCPPNIARVLTSIGHYLYTPREDALYINIYAGNSMEV
                     PVENGTLRLRVSGNYPWQEQVTIAVESPQPVRHTLALRLPDWCIQPQIILNGEEVEQD
                     IRKGYLHITREWQEGDTLNLTLPMPVRRVYGNPLVRHVAGKVAIQRGPLVYCLEQVDN
                     GESLHNLWLPADAPFTTFEGNGLFRHKILIQAPGYRYEQSNPEQQPLWHYDSAPAKRQ
                     PQILTFIPWFSWANRGEGEMRIWVNEETSAIRR"
     gene            complement(33864..35402)
                     /gene="aldB"
                     /locus_tag="ROH59_000856"
     CDS             complement(33864..35402)
                     /gene="aldB"
                     /locus_tag="ROH59_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HDX4803376.1"
                     /translation="MTNNPPSAQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGEIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSYGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(35510..36805)
                     /locus_tag="ROH59_000857"
     CDS             complement(35510..36805)
                     /locus_tag="ROH59_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDX4803377.1"
                     /translation="MAIKSPPGLIPLSHLSGEELLAHLRFNRVTDEKGRYLPFDELQY
                     RIKKGENVDVAWTLTRLARNAAIQRINYCNEAGEQAGFNITPVIAEACELVDKRATAL
                     ALKDQTERLRGAGAELSQLRLEEPITSSQLEGANTTTLVARKMLETGRSPRTEDEHMI
                     AGNARLMAEIPHLLAEPLTPALIRQLHAIGMGGINDAKYRPGEFRETDDVVIADYDGN
                     IVHQPPAAALLPERLEKVCQWLNSHEGYIHPLVRACILHFMLAHEHPFRDGNGRTSRA
                     LFYWYMLKSGYDVFKYISISRLLHAAPVKYAASYQYTESDGMDLTYFLEYQAGVIKRA
                     LQNWQQHIDEITQRSAKLDSVLFSSGVLKRLNPRQVTLLNVMLANPGKEYTVAEISAS
                     LGVSDNTARADLRTIVKEGFAQEKRINNQQAVYVAHYPL"
     gene            complement(36935..38086)
                     /gene="yiaY"
                     /locus_tag="ROH59_000858"
     CDS             complement(36935..38086)
                     /gene="yiaY"
                     /locus_tag="ROH59_000858"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HDX4803378.1"
                     /translation="MAASTFFIPSVNVIGADSLNDAMNMMADYGFTRTLIVTDNMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
     gene            complement(38277..40121)
                     /gene="selB"
                     /locus_tag="ROH59_000859"
     CDS             complement(38277..40121)
                     /gene="selB"
                     /locus_tag="ROH59_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDX4803379.1"
                     /translation="MIITTAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGIDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRV
                     RALHAQNQPTETAHAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRIVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDIHSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPEK"
     gene            complement(40118..41509)
                     /gene="selA"
                     /locus_tag="ROH59_000860"
     CDS             complement(40118..41509)
                     /gene="selA"
                     /locus_tag="ROH59_000860"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDX4803380.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVTKAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQALLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            complement(41607..42215)
                     /locus_tag="ROH59_000861"
     CDS             complement(41607..42215)
                     /locus_tag="ROH59_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HDX4803381.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            complement(42286..43422)
                     /locus_tag="ROH59_000862"
     CDS             complement(42286..43422)
                     /locus_tag="ROH59_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX4803382.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLEPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPNA
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
     gene            complement(43425..43787)
                     /locus_tag="ROH59_000863"
     CDS             complement(43425..43787)
                     /locus_tag="ROH59_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HDX4803383.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            44324..46237
                     /gene="mtlA"
                     /locus_tag="ROH59_000864"
     CDS             44324..46237
                     /gene="mtlA"
                     /locus_tag="ROH59_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDX4803384.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     KTSKVKEEDDIEAAARRVQEMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTENEVKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGRK"
     gene            46557..47705
                     /gene="mtlD"
                     /locus_tag="ROH59_000865"
     CDS             46557..47705
                     /gene="mtlD"
                     /locus_tag="ROH59_000865"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDX4803385.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVDAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGTLPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            47705..48292
                     /gene="mtlR"
                     /locus_tag="ROH59_000866"
     CDS             47705..48292
                     /gene="mtlR"
                     /locus_tag="ROH59_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HDX4803386.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(48303..48512)
                     /locus_tag="ROH59_000867"
     CDS             complement(48303..48512)
                     /locus_tag="ROH59_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803387.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRQLYRPKQVEEK"
     gene            48796..49158
                     /locus_tag="ROH59_000868"
     CDS             48796..49158
                     /locus_tag="ROH59_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HDX4803388.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
     gene            49702..50382
                     /locus_tag="ROH59_000869"
     CDS             49702..50382
                     /locus_tag="ROH59_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HDX4803389.1"
                     /translation="MSMKTLLNVLTIFSLGTLTGCDYIEKASLIDDLAKQQELQKSKI
                     EELEKQQEQYKNKAELFEKQQNNITNSTRILASIVKTVKEKQDEFVFTEFNPLQTQYF
                     ILNNGSVGLAGRVLAIDAVENGSVIRISLVNLLSVPVSNIGFHATWGNEKPTDAKALA
                     KWQQLLFNTTLNSTLQLMPGQWQDINLTLKGVSPNNLKYLKLSINMANLQFDTVQPAE
                     TRQRKNKK"
     gene            50426..54769
                     /locus_tag="ROH59_000870"
     CDS             50426..54769
                     /locus_tag="ROH59_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YadA-like family protein"
                     /protein_id="HDX4803390.1"
                     /translation="MNKIFKVIWNPATGSYNVASETAKSRGKKSGRSKLLISALVAGG
                     LLSSFGALADNYEGQPVDYGNGSAGDGWVAIGKNSKANTFVNGSGASTALGYDAIAEG
                     EYSSAIGSRTHAIGGASMAFGVSAQAIGDRSVALGASSVATGGRSMALGRYAKTNGFT
                     SLAIGDTALADGEKTIALGNTAQAYEIMSIALGDHANASKEYSMALGASSVASAANAI
                     AVGRDSAANGTDSLALGRLSLASAANAIAMGAESEAAENATAIGFNADAIGKSSLALG
                     DNASAGETNSIAIGQGSEASKLDSIALGSNSRSAGENAIALGNNSNAGGKNSLAFGFN
                     TTANGDNAVAIGANSSAGADNTVSVGSSSLKRKIVNMGNGDINNVSSDAINGSQLYAI
                     SKSVSDRLGGYHDDPDNVINSDGTLKAPTYYLQSGQYNNVGEALQSIDNNTLHWDSKS
                     NKYSASHTVFNANGSVKSTSAKNIITDVADGTISATSSDAVNGSQLYNLKQDALLWDG
                     TAFSAKHGTSNTNSKITNVADGAVSASSKDAVNGSQLYDLKQDALLWDGTAFSAKHGT
                     SNTDSKITNVLAGTVSSTSTDAINGTQLQSTASTITSYLGGGAAMSNDGVFTGPQYNI
                     GGKNYTNVGAALTALDNDALLWDATANSNTGAFSAAHGTLKTASKITNVANGDILANS
                     YDAINGSQLYSLADSFTSYLGGGADINNAGVLIAPTYTIGSKTYNNVGDALNAINSSF
                     STSISDALLWDSTANKFSAKHGGTNSIITNVADGTISSTSSDAVNGSQLYDTSKYIAD
                     ALGGDAEVNADGTMTAPTYSIANEDYHSVGEALDALDDNALLWDEDAGAYNASHDGNA
                     SKITNVAAGDLSTTSTDAVNGSQLNATNILVTQNSQMINQLAGNTSETYIEENGAGIN
                     YVRTNDNGLAFNDASASGIGATAVGYNSVAEGDSSVAIGQGSSSSVDTGIALGSSSVS
                     SRVIVKGSRNTSVTENGVVIGYDTTDGELLGALSIGDDGKYRQIINVADGSEAHDAVT
                     VRQLQNAIGAVATTPTKYFHANSTAEDSLAVGEDSLAMGAKTIVNGNAGIGIGLNTLV
                     LADAINGIAIGSNARANHADSIAMGNGSQTTRGAQTNYTAYNMDAPQNSVGEFSVGSE
                     DGQRQITNVAAGSADTDAVNVGQLKVTDAQVSQNTQSITNLNTQVTNLDTRVTNIENG
                     IGDIVTTGSTKYFKTNTDGADANAQGKDSVAIGSGSIAAADNSVALGTGSVADEENTI
                     SVGSSTNQRRITNVAAGVNATDAVNVSQLKSSEAGGVRYDTKADGSIDYSNITLGGGN
                     GGTTRISNVSAGVNNNDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESKLSGGIA
                     SAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGVSMVSANGRWVYKLQGSTNSQGE
                     YSAALGAGIQW"
     gene            55187..56842
                     /gene="lldP"
                     /locus_tag="ROH59_000871"
     CDS             55187..56842
                     /gene="lldP"
                     /locus_tag="ROH59_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDX4803391.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFTSGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP"
     gene            56842..57618
                     /gene="lldR"
                     /locus_tag="ROH59_000872"
     CDS             56842..57618
                     /gene="lldR"
                     /locus_tag="ROH59_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HDX4803392.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGEKEKIQLCFEATLSEDPDLASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFVGDADGARKAM
                     MAHLSFVHTTMKRFDEDQARHARITRLPGDHNEHSREKNA"
     gene            57615..58805
                     /gene="lldD"
                     /locus_tag="ROH59_000873"
     CDS             57615..58805
                     /gene="lldD"
                     /locus_tag="ROH59_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HDX4803393.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAK
                     GNAA"
     gene            58853..59326
                     /gene="trmL"
                     /locus_tag="ROH59_000874"
     CDS             58853..59326
                     /gene="trmL"
                     /locus_tag="ROH59_000874"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDX4803394.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD"
     gene            complement(59379..60200)
                     /gene="cysE"
                     /locus_tag="ROH59_000875"
     CDS             complement(59379..60200)
                     /gene="cysE"
                     /locus_tag="ROH59_000875"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDX4803395.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(60280..61299)
                     /gene="gpsA"
                     /locus_tag="ROH59_000876"
     CDS             complement(60280..61299)
                     /gene="gpsA"
                     /locus_tag="ROH59_000876"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDX4803396.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(61299..61766)
                     /gene="secB"
                     /locus_tag="ROH59_000877"
     CDS             complement(61299..61766)
                     /gene="secB"
                     /locus_tag="ROH59_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HDX4803397.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(61830..62081)
                     /gene="grxC"
                     /locus_tag="ROH59_000878"
     CDS             complement(61830..62081)
                     /gene="grxC"
                     /locus_tag="ROH59_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HDX4803398.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(62222..62653)
                     /locus_tag="ROH59_000879"
     CDS             complement(62222..62653)
                     /locus_tag="ROH59_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDX4803399.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            62897..64441
                     /gene="gpmM"
                     /locus_tag="ROH59_000880"
                     /gene_synonym="pgmI"
     CDS             62897..64441
                     /gene="gpmM"
                     /locus_tag="ROH59_000880"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDX4803400.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRTFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            64451..65734
                     /gene="envC"
                     /locus_tag="ROH59_000881"
     CDS             64451..65734
                     /gene="envC"
                     /locus_tag="ROH59_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HDX4803401.1"
                     /translation="MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADE
                     RDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNK
                     QIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEA
                     TRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            65738..66697
                     /locus_tag="ROH59_000882"
     CDS             65738..66697
                     /locus_tag="ROH59_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HDX4803402.1"
                     /translation="MFPFRRNVLAFAALLALSSPVIAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVL
                     QQLVYNLPPDITLVKASSLLNEPQVDTSTPPKNTVPDTPRNPFRGVKLCKPKKPLEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKLNASAN"
     gene            complement(66684..67718)
                     /gene="waaH"
                     /locus_tag="ROH59_000883"
     CDS             complement(66684..67718)
                     /gene="waaH"
                     /locus_tag="ROH59_000883"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HDX4803403.1"
                     /translation="MMNSTNKLSVIIPLYNAGDDFRTCMESLITQTWTALEIIIINDG
                     STDNSVEIAKHYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPTDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYKYYLH
                     NTSVSRLHRQGNKNLNYQRHYIKITRLLEKLNRNYADKITIYPEFHQQITYEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(67957..68982)
                     /gene="tdh"
                     /locus_tag="ROH59_000884"
     CDS             complement(67957..68982)
                     /gene="tdh"
                     /locus_tag="ROH59_000884"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDX4803404.1"
                     /translation="MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(68992..70188)
                     /gene="kbl"
                     /locus_tag="ROH59_000885"
     CDS             complement(68992..70188)
                     /gene="kbl"
                     /locus_tag="ROH59_000885"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDX4803405.1"
                     /translation="MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPELIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLSAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMHE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGK
                     QLGVIA"
     gene            70402..71334
                     /gene="rfaD"
                     /locus_tag="ROH59_000886"
     CDS             70402..71334
                     /gene="rfaD"
                     /locus_tag="ROH59_000886"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HDX4803406.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA"
     gene            71344..72390
                     /gene="rfaF"
                     /locus_tag="ROH59_000887"
     CDS             71344..72390
                     /gene="rfaF"
                     /locus_tag="ROH59_000887"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HDX4803407.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYVALAYDKGIMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNALLLQEEA"
     gene            72394..73353
                     /gene="rfaC"
                     /locus_tag="ROH59_000888"
     CDS             72394..73353
                     /gene="rfaC"
                     /locus_tag="ROH59_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HDX4803408.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSATL
                     VTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQMVCRAPRENLINLNSQAVLEKLSSL"
BASE COUNT        18115 a        19100 c        18588 g        17628 t
ORIGIN      
        1 cgataaaaaa agcctgccag atggcaggct ttttaataac ggcgttatta ctgcaacagc
       61 gaaatatccg caacgcgcag gaacagttcg cgcagttttt ccagcatggt cagacggttg
      121 atacgcaatt ctttatcatc aaccatgacc atcactttat cgaagaaagc atcgaccggt
      181 tcacgcagct cagccagttc gaccagcgca tcctggtaac gaccttccgc aaagtacggc
      241 tccagcttgt cacgtagcac cacaacctgc atcgccagtt taatttcttc cggctctttc
      301 agagtagagg cattcacgcg atcgctcagc acttcatcag atttcgccag gatgttagat
      361 acacgcttgt tcgccgccgc cagtgctgca gctgcttcca gggtacggaa gtgcgatacc
      421 gctttcatac gggcatcgaa atcagccgga cgagtcggac gacgcgccag taccgcctgg
      481 atggtgtcaa cggtgtaacc ttcgtcctga taccaggcgc ggaagcgacc gagcataaag
      541 tcgataacat catcaaccac gttggcatta gtcagcttat cgccatacag acgcactgct
      601 tcttcggtca gcgtttgcag atcaaggttg aggttcttct caacgataat acgcagcacg
      661 ccaagtgcgg cacgacgcag cgcaaacggg tctttgtcgc ctttcggatg ctggccgata
      721 ccgaagatac ccgccagggt atccatcttg tcagcaatcg ccagcgcaca ggctaccggg
      781 ttagacggca ggtcatcacc ggcaaagcgc ggctgatact gctcattcag cgcgacagct
      841 acgtcttccg cttcgccatc gtgacgcgcg tagtgcatcc ccataacgcc ctgggtgtcg
      901 gtgaactcga agaccatgtt ggtcatcagg tcacacttag acagcaggcc cgcacgggta
      961 gcgtggttaa cgtcagcgcc aatctgttca gcaatccagc cggccagcgc ctgaatgcgg
     1021 tcagttttgt cgcgcagcgt ccccaactgt tgctggaaca acacggtttg caggcgcggc
     1081 aggttatctt caagacgttt tttacggtcg gtattgaaga agaactcggc atccgccaaa
     1141 cgtggacgaa cgactttctc gttaccggag ataatctgct gcggatcttt cgattcgatg
     1201 ttggcaacga agataaagtt cggcagcagt ttgccgtcgt tcgcatacac cgggaagtac
     1261 ttctggtcac ctttcatggt gtaaaccagt gcttcagacg gcaccgcgag gaatttctct
     1321 tcgaatttcg cggtcagaac gaccggccac tccaccagcg aagccacttc ttccagcagg
     1381 ctttcgctta aatcagcgtt accgccaatc ttacgtgctg cttcttcagc atcggcttta
     1441 atcttcgcct tacgttcttc gtaatcggcg atgactttcc cgcgctcacg cagaatttct
     1501 ggatactgat cggcattgtc gatagtgaat tccggctcgc ccataaagcg gtggccgcga
     1561 atcacgcgat cggactgaat acccagaatg gtagccggaa taactttgtc gcccagcagc
     1621 agggtcacgg tgtgaaccgg acgcacaaag tgcacgtcgc ttgcgcccca acgcatcagt
     1681 ttcgggatcg gcagtttcgc cagcgaagtc gcaaccatat tcggcagcag tgcttcggtg
     1741 ctttcgccct tcacatgggc gcgatacagc agccattcgc ctttatcggt agtcagacgc
     1801 tcagcctggt caacggtaat accgcaacca cgcgcccaac cttctgccgc tttactcggt
     1861 ttgccttcag cgtcgaacgc ctgagcaatt gccggaccac gtttttcgat ttcacgatcc
     1921 ggttgcgcct ccgccaggtt agcgactttc agcgccagac gacgcggagc agcaaaccat
     1981 tgaacggtgc cgtgtgcgag gccagcgtta tccagctccg cagtaaagtt cgcagcaaag
     2041 gactcagcca ggctgcgtag tgcttttggt ggcagctctt cagtgccgat ttccaccaga
     2101 aaagttttct cagacatagc cgcctcttac ttatctttgt tgcacatcgg gaagccgagg
     2161 gcttcacggg aagcgtagta tgcttctgcc actgctttgg tcagggtgcg aatgcgcaga
     2221 atatagcgct gacgctcggt gacggagatg gctttacgcg catccagcag gttgaagctg
     2281 tgggcggctt tcagaatacg ctcgtaggct ggcagcggca gcggattttc cagcgccagc
     2341 agttgctgcg cttctttctc gtactgctcg aagcaggtga acaggaagtc cacatccgcg
     2401 tattcgaagt tgtaagtgga ctgctccact tcgttctgat ggaacacgtc gccgtaggtg
     2461 gttttaccca gcgggccgtc gctccagacc aggtcgtaaa cgctgtctac gccctgaatg
     2521 tacatggcca gacgttccag accgtaggtg atctcaccgg taaccggttt acattccaga
     2581 ccaccaacct gctggaagta agtgaactgc gtcacttcca tgccgtttag ccacacttcc
     2641 cagcccagcc cccaggcacc cagcgtcggg ttttcccagt tatcttccac gaaacggatg
     2701 tcgtggatgg tcgggtccat gcccagctct ttcagagaac cgaggtacag ctcctgaata
     2761 ttgtccggcg atggcttaat gaccacctgg aactgatagt agtgctgtaa acggttgggg
     2821 ttttcgccgt agcgaccatc ggtcgggcga cgagaaggct gaacataagc agccgccatc
     2881 ggttctggcc ccagcgcgcg cagacaggtc attgggtgag aggttcccgc gccgacttcc
     2941 atgtccaatg gttgaacaat ggtgcagccc tggcgagccc agtaatcctg taaggtcagg
     3001 atcaagccct ggaaggtcct ggtatcaaac ttttgcatat tatttcgtgc tggatacgtg
     3061 tggatttaaa ggaagggatc agtatacccg ctggatggaa gatatacagt acgaaacggg
     3121 aaaaagcagg gcttaacgca tggaaagatg caaaaaatgg ccatccgcgt caaaagaaca
     3181 gacaaactgc tctttccgga aggtataacc gcgcatttca tagcttccct ggaactgttc
     3241 gaaggcggtg acgtcgattt tttgctcgcc ggtgttataa cgttttgccg cctgatcctt
     3301 gcataacgct tccatattca acgaacgcag aggatcaacc tttacccgtt gtgctttctg
     3361 cacgggtggc ggtgtagaac aacccactag cacaataagc gccattgccg gaaagaaagc
     3421 gttcatcatc attaaattac cgtctggttt gcaggtgagt cttattattt atatcggtat
     3481 agtggctgat atcttacgaa tttccttaag cctctataag ctgtagtgat aaaactcaga
     3541 ttattccagt gcgccaactg aatgatttat cggtcagact ttttttaacc agatacagag
     3601 acacagatgc agcccaaaat ttactggatt gataacctgc gagggatagc gtgtttaatg
     3661 gtggtgatga ttcacaccac tacctggtat gtgatcaatg ctcatagtgt tagccccatc
     3721 acctgggata tcgccaatgt tctgaattct gcctctcgtg tcagcgtgcc gctatttttc
     3781 atgatttccg gctatctctt ttttggcgaa cgcagcgccc agtcgcgtca tttcttgcgt
     3841 atcggcttat gcctgttttt ttatagcgca atcgcgctgc tctacattgc gctgtttacc
     3901 tccatcaatg tggagttagc gctgaaaaac ctgctgcaaa agccagtgtt ttaccattta
     3961 tggtttttct tcgcgattgc agtgatttat ctggtttcac cgctgattca ggtgaagaac
     4021 gtcggcggaa aaatgttgct ggtgctaatg gtggtgattg gtatcatcgc taacccaaac
     4081 accgtgccgc agaaaatcga cggttttgaa tggctgccaa ttaacttata tatcaatggc
     4141 gatacttttt actacatcct ttatggcatg ttgggccgcg ctatagggat gatggacaca
     4201 cagcataaag cactgtcgtg ggtgagcgcc gcactgtttg cgacgggggt ttttattatc
     4261 tctcgtggga cattatatga attacagtgg cgcggaaatt ttgccgatac ctggtatctt
     4321 tactgtgggc cgatggtttt tatctgcgca atcgcgttat tgactctggt taaaaacacg
     4381 ctgtatacgc gtaccatttg cggacttggc ttaatctccc gccattcgtt aggtatatac
     4441 gggttccatg cattgattat ccatgcactg cgcacccggg ggattgagct taaaaactgg
     4501 ccaatactgg atattatttg gatcttttgt gcgacgctgg cagtgagttt attactttct
     4561 atgctggtac aacgaatcga cagaaacaga ttagtgagtt aagtagaagc ccggtcacat
     4621 tggactgacc gggcttacgt gaattattcg ctgtattctt cctgggtaac ctgtgtttct
     4681 tttggtgggt ttattccggc atcacgaata ttcttctgca ccgctactgc accaaacaag
     4741 cttaagaaga aagccagccc ataaaagcct ttttcgctga gtaataacgt tgcattccat
     4801 agacctacca gcaacaacgc aacagagata ataaagaccg tcaggcaagt catataataa
     4861 atgggggtgg taggtatgcc ttcatacttg tcccgaacgg tcttttgata agacgccgcg
     4921 gaaaacaaac ctaataccag tacggcaaaa taataccctt tttcatttaa ctgcatctct
     4981 gcattccata gtcctaacag ataggtaaca ataccgccaa taagggctac ccatgaaaca
     5041 atactaaatg ccggagaata ggttgatatt ttgttgtcca tcacagtatt cctttcattc
     5101 ctgaatgtgt aagaacttta tgttgctcat gccgagcgaa acaaacgcat ttgaccaaac
     5161 aagcagacaa aaaaggcgat gggatagatc accatttcat aagcattgat aggtgcgttt
     5221 aaaacaccga taaacaagag accgatagtg attaacgcta ccaactgaca gacgtggata
     5281 aaaaaatcat ccagttgccc aagtttttct gcgcgaagat atgcatagtt gccaaaagtt
     5341 gccgtcatta acacgccaag aaaatagcct tttccactta acaatgggca tgagatccat
     5401 agcccaacca gataaaccag cgccccgaca acaaataata gttttgccac agtctttgag
     5461 gttttcataa cgatctccat atctaccagc gatacattac gagtaaccaa cgaaagacaa
     5521 aactgaaaaa tgccattaac aaatgatttt cagaataaat tcatactaaa tattaattaa
     5581 ttatttatat atatagatgt gaattatccc ccacccggtc aggcagggga taacgtttac
     5641 gccattaatg gcagaagttg ctgatagagg cgacggaacg tttctcgtcg tggctgataa
     5701 gcggcataac gctgcgcatc tggtagatgc gactgttcta acggtagttg cggcaacaac
     5761 tcaatgagcg atttctctgg attcgccgca atctgcgcca gccttgctgc gcccagtgct
     5821 ggccccacat cgccacccgt gcggtaatcc agttgctgac cgctaatgtc cgccagcatt
     5881 tgacgccagt actcactacg cgccccgcca ccaatcaacg taacactttg cggtttaatg
     5941 ccgcaggcat gcacgacatc catgccatct gccagcgcat aacccacgcc ttccagcact
     6001 gctcgcgcca gttcattggg gccatgttga tgagtcaaac caaagaaaac ccctttcgcc
     6061 tggggattat tgtgtggtgt acgctcgcca gaaagataag gcagaaacca aactggctcg
     6121 gcactttcat cagcctgtcg agctgcagtg attaaagcag ggacattgct caggccggtt
     6181 aatttcgcgg cccaatccag acacgaagcc gcactcagca ttacagacat taaatgccaa
     6241 cgttgcggta acgcatggca aaagctatgt acggcgcttt ctggcttgct taagaaccct
     6301 tcgctgacag caaaatagac ccccgacgtc cccagcgata acattgcctg attagcatca
     6361 accattccca caccaaccgc accagctgca ttgtcgccac cgcctgcgac aactggcacc
     6421 gccgccatac cccacgcttt cgcaacttca ggtagcaaag caccagtaat ttcgctgcct
     6481 tcgtataatg cgggcatctg gtcacgagat aagtggcaag cctgcagcat gtcgtcactc
     6541 cagtcacgct ttgcgacatc cagccacatg gtgccagctg cgtcagacat atcgctggca
     6601 aactcccccg tcatacgcag acgcaagtaa tctttcggta ataatacttt atcgatttga
     6661 cggaatatct ccggctcatg ccgctgaacc catagcaatt taggcgcagt aaatccgggc
     6721 atcatcaggt tgccggtaat cacccgcgat tgcggaactc gcgcttccag caaagtgcac
     6781 tcttgcgcac agcgcccgtc gttccacaaa atggcagggc gtaacacccg ttgctgagca
     6841 tccagtaagg ttgcaccatg catctgtccg gcaataccta atgctttaac gtcttgcaga
     6901 gaatgctgaa cgcccagagc tttcattgcg cgatcagttg cctgccacca ctgttccggg
     6961 tcttgttccg accagagtgg atgcgggcgc gaaacggtca gcttttccgt ttgcgcagca
     7021 accacctcac cctgctcgtt gagcaaaata acttttacgc ccgaggtgcc aagatctatc
     7081 ccgatataca tatcgatcgt tccttaaaaa atgcccggta tcgctaccga taaccgggcc
     7141 aacggactgc acagttaacc gttatttgtc gaacagataa tgatttacca gattttccag
     7201 ttgctcctgg cgaccactct gatgcaccgg agacaaatta tgttcctgag catatttggc
     7261 taaatctgcc agtgacattt ggcctttcag gatttgctgg cctaattcac tattccagcc
     7321 ggaataacgc tgcgcgatgc gtttatccag ctcgccatct tcaatcatgc gcgctgcaat
     7381 tttcagcgcc aacgccatcg tatccatcgc gccgatatga ccgtaaaaca gatcatattt
     7441 atcagtactt tgacgacgta ctttggcatc gaagttcaga ccaccggtgg tgaaaccgcc
     7501 tgctttgaga atttcataca tcaccagcgc attctcttcc acactgttcg ggaactggtc
     7561 ggtgtcccag cccagttgcg catcgccacg gttggcgtcg acagaaccga acaggccaag
     7621 cgcaatggcg gtggctattt catgatggaa agagtgacct gccagcgtcg cgtggttagc
     7681 ttcaatgttc agtttaatct ctttttccag accaaactgt ttcaggaagc catagaccgt
     7741 cgcagcatcg taatcatatt gatgtttggt cggttcttgc ggtttcggtt cgataagcaa
     7801 cgtgccctgg aaaccgattt tatgtttatg ctcaaccacc atctgcataa agcggcccag
     7861 ctgttcacgc tcctggcgca agtcggtatt taacagcgtt tcgtaacctt cacgaccacc
     7921 ccacaggaca tagttttcac cgcccaattt atgggttgct tccatcgctg taacaacttg
     7981 cgttgccgcc caactgaaga cttcaggatc tgggttcgtc gccgcacccg cgccatagcg
     8041 agggtttgta aagcagttag cagttcccca cagcagcttc acgccgctct cttcttgctt
     8101 gcctgccagg acatcaacca tttgcgcaaa attattgatg tactctttta acgacgcgcc
     8161 ctcaggggaa acatccacat cgtggaagca ataaaatggc acatgtaact tgtggaaaaa
     8221 ctcaaatgcg acatctgctt tacgcttcgc caacgccagt gcctcaccag gctgctgcca
     8281 cggacgatta aacgccccca caccaaacat atccgccccg ttccagcaga aggtgtgcca
     8341 gtagcaggcg gcaaaacgca agtgctcttc catacgcttg cccaacacca gttcgtcggg
     8401 attgtagtga cggaatgcta acgggtttga ggattttgag ccttcataac gaacgcgatc
     8461 gagctggtca aaataggctt gcatattgaa ctccataatc aggtaatgcc gcgggtgatg
     8521 gatgatgtcg taatattggg cactcccttt cagttgctca attatgttat ttcacactgc
     8581 tattgagata attcacaagt gtgcgctcgc tcgcaaaata aaatgggatg atgaaactgg
     8641 gtaattcctc gaagagaaaa atgcaataag tacaattgcg caacaaaagt aagatctcgg
     8701 tcataaatca agaaataaac caaaaatcgt aatcgaaaga taaaaatctg taattgtttt
     8761 cccctgttta gttgctaaaa attggttacg tttatcgcgg tgattgttac ttattaaagc
     8821 tgtcctctaa ctacagaagg ccctacacca tgaaaataaa gaacattcta ctcacccttt
     8881 gcacctcact tctgcttacc aacgttgcgg cacacgccaa agaagtcaaa ataggtatgg
     8941 cgattgatga tctccgtctt gaacgctggc aaaaagatcg agatattttt gtgaaaaaag
     9001 cagaatctct cggcgcgaaa gtatttgtac agtctgcaaa tggcaatgaa gaaacacaaa
     9061 tgtcgcagat tgaaaacatg attaaccggg gtgtcgatgt tcttgtcatt attccttata
     9121 acggtcaggt attaagtaac gttgtaaaag aagccaaaca agaaggtatt aaagtattag
     9181 cttacgaccg tatgattaac gatgcggata tcgattttta tatttctttc gataacgaaa
     9241 aagtcggtga actgcaggca aaagccctgg tcgatattgt tccgcaaggt aattacttcc
     9301 tgatgggcgg ctcgccggta gataacaacg ccaagctgtt ccgcgccggg caaatgaaag
     9361 tattaaaacc ttatgttgat tccggaaaaa ttaaagtcgt tggtgaccaa tgggttgatg
     9421 gctggttacc ggaaaacgca ttgaaaatta tggaaaacgc gctaaccgcc aataataaca
     9481 aaattgatgc tgtagttgcc tcaaacgatg ccaccgcagg aggggcaatt caggcattaa
     9541 gcgcgcaagg tttatcaggg aaagtagcaa tttccggcca ggatgcggat cttgcaggta
     9601 ttaaacgtat tgctgccggt acgcaaacta tgacggtgta taaacctatt acattgttgg
     9661 caaatactgc cgcagaaatt gccgttgagt tgggcaatgg tcaggagcca aaagcggata
     9721 ccacactgaa taatggcctg aaagatgttc cctcccgcct gctgacaccg atcgatgtga
     9781 ataaaaacaa catcaaagat acggtagtta aagacggatt ccacaaagag agcgagctgt
     9841 aagcgttacg ccccggcgcg gagcgggggc gtgatttctc tccatgccgc gttaattaat
     9901 tggcttaggt ggagtcgtta tgccttatct acttgaaatg aaaaatatta ccaaaacctt
     9961 cggcagtgtg aaggcgattg ataacgtcag cttgcggttg aatgctggcg aaatcgtctc
    10021 actctgtggg gaaaatgggt caggtaaatc aacgctgatg aaagtgctgt gtggtattta
    10081 tccccatggt tcctacgaag gcgaaattat ttttgcggga gaagagattc aggcgagtca
    10141 catccgcgat accgaacgca aaggtatcgc cattattcac caggaattgg cgctggtgaa
    10201 agaactgacc gtgctggaaa atatcttcct gggtaacgaa ataacccata atggcattat
    10261 ggattatgac ctgatgacgc tacgctgtca gaagctgctc gcacaggtca gtttatccat
    10321 ttcacctgat acccgcgttg gcgatttagg acttgggcaa caacaactgg ttgaaattgc
    10381 caaggcactt aataaacagg tgcgtttgtt aattctcgat gagccgacag cctcattaac
    10441 tgagcaggaa acgtcggttt tactggatat tattcgcgat ctacaacagc acggtatcgc
    10501 ctgtatttat atttcgcaca aactcaacga agtcaaagcg atttccgata cgatttgcgt
    10561 tattcgcgac ggtcaacaca ttggtacgcg tgatgctgct ggaatgagtg aagacgatat
    10621 tatcaccatg atggtcgggc gagagttaac cgcgctttac cctaatgaac cacataccac
    10681 cggagatgaa atattacgta ttgaacatct gacggcatgg catccggtta atcgtcatat
    10741 taaacgagtt aatgatgtct cgttttccct gaaacgtggc gaaatactgg gtatcgccgg
    10801 actcgttggt gccggacgta ccgagactat tcagtgcctg tttggtgtgt ggcccggaca
    10861 atgggaaggg aaaatttata ttgatggcaa acaggtagat attcgtaact gtcagcaagc
    10921 catcgcccag gggattgcga tggtacccga agacagaaag cgcgacggca tcgttccggt
    10981 aatggcggtt ggtaaaaata ttaccctcgc cgcactcaaa aaatttaccg gtagtattag
    11041 ccagcttgat gacgcggcag agcaaaaatg tattctggaa tcaatccagc aactcaaagt
    11101 taaaacgtcg tcccccgacc ttgctattgg acgtttgagc ggcggcaatc aacaaaaagc
    11161 gatcctcgct cgctgtctgt tacttaaccc gcgcattctc attcttgatg aacccaccag
    11221 gggtatcgat attggcgcga aatacgagat ctacaaatta attaaccaac tcgtccagca
    11281 gggtattgcc gttattgtca tctcttccga attacctgaa gtgctcggcc ttagcgatcg
    11341 tgtactggtg atgcatgaag ggaaactaaa agccaacctg ataaatcata acctgactca
    11401 ggagcaggtg atggaagccg cattgaggag cgaacatcat gtcgaaaagc aatccgtctg
    11461 aagtgaaatt agccgtaccg acatccggtg gcttttccgg gctgaaatca ctgaatttgc
    11521 aggtcttcgt gatgattgca gctatcatcg caatcatgct gttctttacc tggaccaccg
    11581 atggtgccta cttaagcgcc cgtaacgtct ccaacctgtt acgccaaacc gcaattaccg
    11641 gcatcctcgc ggtaggaatg gtgttcgtca taatttctgc tgaaatcgac ctttccgtcg
    11701 gctcaatgat ggggctgtta ggtggcgtcg cggcgatttg tgacgtctgg ctaggctggc
    11761 ctttgccact taccatcatt gtgacgttgg ttctgggact gcttctcgga gcctggaacg
    11821 gatggtgggt cgcgtaccgc aaagtccctt catttattgt caccctcgcg ggcatgttgg
    11881 catttcgtgg catactcatt ggcatcacca acggcacgac tgtttccccc accagcgccg
    11941 cgatgtcaca aattgggcaa agctatctac ctgccagcac cggcttcatc attggcgcgc
    12001 ttggcttaat ggcttttgtt ggctggcaat ggcgcggaag aatgcgccgt caggctttgg
    12061 gtttgcagtc tccggcctct accgcagtag tcggtcgcca ggctttaacc gctatcatcg
    12121 tattaggcgc aatctggctg ttgaatgatt accgtggtgt tcccactcct gttctgctgc
    12181 taacgttact gttattgggc ggcatgttta tggcaacgcg gacggcattt ggacggcgca
    12241 tttatgccat cggcggcaat ctggaagcgg cacgtctctc cgggattaac gttgaacgca
    12301 ccaaacttgc cgtgttcgct attaacggat taatggtagc catcgccgga ttaatcctca
    12361 gttctcgact cggcgctggt tcaccttctg cgggaaatat cgccgaactg gacgcaattg
    12421 cagcatgtgt gattggcggc accagtctgg caggcggcgt cgggagcgtg gccggagcgg
    12481 taatgggggc attcatcatg gcttcgctgg ataacggcat gagtatgatg gatgtaccga
    12541 ccttctggca gtatatcgtt aaaggtgcga ttctgttgct ggcagtatgg atggactccg
    12601 caaccaaacg ccgttcttga ttttgataaa aattttctca aagccggtaa cgtattaccg
    12661 gttttgagtt tttgcatgat tcagcaggaa aagaaccatg tttactaaac gtcaccgcat
    12721 cacattactg ttcaatgcca ataaagccta tgaccggcag gtagtagaag gcgtagggga
    12781 atatttacag gcgtcacaat cggaatggga tattttcatt gaagaagatt tccgcgcccg
    12841 cattgataaa atcaaggact ggttaggaga tggcgtcatt gccgacttcg acgacaaaca
    12901 aatcgagcaa gcgctggctg atgtcgacgt ccccattgtt ggggttggtg gctcgtatca
    12961 ccttgccgaa agttacccac ccgttcatta cattgccacc gataactatg cgctggttga
    13021 aagcgcattt ttgcatttaa aagagaaagg cgttaaccgc tttgcttttt atggtcttcc
    13081 ggaatcaagc ggtaaacgtt gggccactga acgcgaatat gcatttcgtc agcttgtcgc
    13141 tgaagaaaag tatcgcggag tggtttatca ggggttagaa accgcgccag agaactggca
    13201 acacgcgcaa aatcggctgg cagactggct acaaacgcta ccaccgcaaa ccgggattat
    13261 tgccgttact gacgcccggg cgcggcatat tctgcaagta tgtgaacatc tacatattcc
    13321 cgtaccggaa aaattatgcg tgattggcat cgataacgaa gaactgaccc gctatctgtc
    13381 gcgtgtcgcc ctttcttcgg tcgctcaggg cgcgcggcaa atgggctatc aggcggcaaa
    13441 actgttgcat cgattattag ataaagaaga aatgccgcta cagcggattt tggtcccacc
    13501 agttcgcgtc attgaacggc gctcaacaga ttaccgctcg ctgaccgatc ccgccgttat
    13561 tcaggctatg cattacattc gtaatcacgc ctgtaaaggg attaaagtgg atcaggtact
    13621 ggatgcggtg ggcatatcac gctccaatct tgagaagcgt tttaaagaag aggtgggtga
    13681 aaccatccat gccatgattc atgccgaaaa gctggagaaa gcgcgcagtc tgctgatttc
    13741 aaccaccttg tcgatcaatg agatatcgca aatgtgcggt tatccatcgc tgcaatattt
    13801 ctactctgtt tttaaaaaag catatgacac gacgccaaaa gagtatcgcg atgtaaatag
    13861 cgaggtcatg ttgtagcgat gatgagaatt gtcggcgtcg cttcaggtaa ctcagcacaa
    13921 ccacctgatg ggagcaaaag ccttatccga ctgacaagtc ggataaggct cgaggaaatg
    13981 caattacata tgcgccgcga ttaaccgttg gttatcctgg tacattgcaa acaggtagtt
    14041 gttataactc ttccctttgg tcgagtagcc cttcagcttg tgaatcatcg ctgtggcagt
    14101 cacttcctga tccgctttac gcagctgtgc acgcgattta cggaacgaag agtaagccgg
    14161 gtgcgtattg aggtttgtaa cataggcgct caccgattct ttaacagaac taaactgtga
    14221 gtaccctttc actttacccg gcgcattggt acaacgtcct ttcatgcatt tcatgccgaa
    14281 aagattgttg ttgttgcgcg ccagctttga cgttccccaa ccgctttctg ctgcagccat
    14341 cgtcgccacc atactggtag ggataatgtc tacgcgttca agcaaggtat tccacgggat
    14401 ttttcgcgta ttaccagacc acttcacctt gtagcgtttg gcgatgtctt tcagacgcgc
    14461 acgctcagca ggtgaccatt ggccctgata ctgttttgaa atcagccagt tacgttccgc
    14521 agtaatggcc gcattttggc tggtaatgta aggcattaca gtccggagaa acgccttttt
    14581 ccttggtgtt ccggaagggt attttcgcaa atcaggaagt gaactactct ttgcactatt
    14641 gcgagaatac tcttgtttac tgcttacctg tttattacta gctttagtta agtgggactt
    14701 ttgactcgct gttgttgtgt gcgtcttcgc taacacctca ctcgaaaaca ccagagtgag
    14761 taacataaga atcatcgccc catatcgtcg tatgggagtc aaaatcatca ggtctcctgg
    14821 tcggatttaa tcattccaac accttatatt ttttacaaat ttgagagttg aatctcaaat
    14881 catatcaaaa atagctgtca agagcacccc aaggaatagt ccaaatctga aactatgtca
    14941 cgagttaacg attcagattg gcgctaaatc gcagaaaatg tggggtttat cgcaaaattc
    15001 agccgttttt tgcgcgcgat cgctcaccct tgcttctcat cctgtggagt taccgctcag
    15061 ggatgagttt tgtctggctt atcgctggca aactgtctga aatcgcagca ataaggactc
    15121 atccgccatg aaactcgccg cctgttttct gacactcctt cctggcttcg ccgttgccgc
    15181 cagctggact tctccggggt ttcccgcctt tagcgaacag gggacgggaa catttgtcag
    15241 ccacgcacag ttgcccaaag gtacgcgtcc actaacgcta aattttgacc aacagtgctg
    15301 gcagcctgcg gatgcgataa aactcaatca gatgctttcc ctgcaacctt gtagcaacac
    15361 gccgcctcaa tggcgattgt tcagggacgg cgaatatacg ctgcaactag acacccgatc
    15421 cggtacacca acattgatga tttccatcca gaacgccgtc gaaccggtag caagcctggt
    15481 ccgtgaatgc ccgaaatggg atggattacc gctcacactg gatgtcagcg ccacttttgc
    15541 ggagggagcc gcagtccggg attattacag ccagcaaatt gcgatagtga agaacggtca
    15601 aataacgtta caacccgctg ccaccagcaa cggtttactc ctgctggaac gggcagaaac
    15661 tgacacatcc gcccctttcg actggcataa cgccacggtt tactttgtgc tgacagatcg
    15721 tttcgaaaac ggcgatccca gtaatgacca gagttacgga cgtcataaag acggtatggc
    15781 ggaaattggc acttttcacg gcggcgattt acgcggcctg accaacaaac tggattacct
    15841 ccagcaactg ggcgtcaatg ctttatggat aagtgcccca tttgagcaaa ttcacggctg
    15901 ggtcggcggc ggtacaaaag gtgatttccc gcattatgcc tatcatggtt attacacaca
    15961 ggactggacg aatcttgatg ccaatatggg cagtgaagcc gatctacgga cgctggttga
    16021 tagcgcgcat cagcgcggta ttcgtattct ctttgatgtc gtgatgaacc acactggcta
    16081 tgccacgctg gcggatatgc aggagtatca gtttggcgcg ttatatcttt ctggtgacga
    16141 agtgaaaaaa acgctgggtg aacgctggaa cgactggaaa cctgccgccg ggcaaacctg
    16201 gcatagcttt aacgattaca ttaatttcag cgacaaaaca ggctgggata aatggtgggg
    16261 aaaaaactgg atcagaacgg atatcggcga ttacgacaat cctggattcg acgatctcac
    16321 tatgtcgctg gcctttttgc cggatatcaa aaccgaatca actaccgctt ctggtctgcc
    16381 agtgttctat aaaaacaaaa cggataccca cgctaaaatc atcgacggct ttacccctcg
    16441 cgattactta acccactggt taagtcagtg ggtccgcgac tatgggattg atggttttcg
    16501 ggtcgatacc gccaaacatg ttgagttgcc cgcctggcag caactgaaaa ccgaagccag
    16561 cgctgcactt cacgaatgga aaaaagctaa ccccgacaaa gcattagatg acaaaccttt
    16621 ctggatgacc ggtgaagcct ggggccacgg cgtgatgcaa agtgactact atcgccacgg
    16681 cttcgatgcg atgatcaatt tcgattatca ggagcaggcg gcgaaagctg tcgattgtct
    16741 ggcgcagatg gatacgacct ggcagcaaat ggcggagaaa ttgcaggatt tcaacgtgtt
    16801 gagctacctc tcgtcgcatg atacccgcct gttccgtgaa gggggcgaca aagcagcaga
    16861 gttattatta ttagcaccag gcgcggtaca aattttttat ggcgatgaat cctcgcgtcc
    16921 gttcggtcct accggttctg atccgctgca aggtacgcgt tcggatatga actggcagga
    16981 tgttagcggt aaatctgccg ccagcgtcgc gcactggcag aaaatcagcc agttccgcgc
    17041 ccgccatccc gcaattggcg cgggcaaaca aacgacactt tcgctgaagc agggctacgg
    17101 ctttgttcgt gagcatggcg acgataaagt gctggtcatc tgggcggggc aacagtgact
    17161 tttccggctt cccgttcgtg agtacctcgg gaagccgcca accaggataa aatgtcagcc
    17221 ctaatcagca ttgcaggata aagccccgct cactcttcaa cagaccgatt tgcaccccag
    17281 caaatgtagc gttattgtta ccttccttgc tacagagttc gacagatatc ccgctatgac
    17341 attctccctt tttggtgaca aatttacccg ccactccggc attacgctgc tgatggaaga
    17401 tctgaacgac ggtttacgca cgcctggcgc gattatgctc ggcggcggta atccggcgca
    17461 gatcccggaa atgcaggact acttccagac gctactgacc gacatgctgg aaagtggcaa
    17521 agcgactgat gcactgtgca attacgacgg tccacagggg aaaacggagc tactcacact
    17581 gcttgccgga atgctgcgcg agaagttggg ctgggatatc gaaccacaga atattgcact
    17641 aacaaacggc agccagagcg cgtttttcta cttatttaat ctgtttgccg gacgccgtgc
    17701 cgatggtcgg gtcaaaaaag tgctgttccc gctggcaccg gaatacattg gctacgctga
    17761 cgccggactg gaagaagatc tgtttgtctc tgcgcgtccg aatattgaac tgctgccgga
    17821 aggccagttt aaataccacg tcgattttga gcatctacat attggcgaag aaaccgggat
    17881 gatttgcgtc tcccggccga cgaatccaac aggcaatgtg attactgacg aagagttgct
    17941 gaagcttgac gcgctggcga atcaacacgg cattccgctg gtgattgata acgcttatgg
    18001 cgtcccgttc ccgggtatca tcttcagcga agcgcgcccg ctatggaatc cgaatatcgt
    18061 gctgtgcatg agtctttcca agctggggct acctggctcc cgctgcggca ttatcatcgc
    18121 caatgaaaaa atcatcaccg ccatcaccaa tatgaacggc attatcagcc tggcacctgg
    18181 cggtattggt ccggcgatga tgtgtgaaat gattaagcgt aacgatctgc tgcgcctgtc
    18241 tgaaacagtc atcaaaccgt tttactacca gcgtgttcag gaaactatcg ccatcattcg
    18301 ccgctattta ccggaagatc gctgcctgat tcataaaccg gaaggagcca ttttcctctg
    18361 gctatggttt aaggatttgc ccattacgac cgagcagctc taccagcgcc tgaaagcacg
    18421 cggcgtgctg atggtgccgg ggcacaactt cttcccggga ctggataaac cgtggccgca
    18481 tacgcatcaa tgtatgcgca tgaactacgt accagagccg gagaaaattg aggcgggtgt
    18541 gaagattctg gcggaagaga tagaaagagc ctgggctgaa agccattaat acgctattcc
    18601 ggcgttgaga aacgccggaa aaacgtttca aacaggctgc tgccgtagcc gatgccgctg
    18661 cactttctcg acatccatgc actgcaacgc ctttgtcggg caggcttcaa cacaggccgg
    18721 ccccgtcgcc cgatgccagc acagatcgca cttaatcgcc ctcgcctttt tgcgcgaaga
    18781 aacgacctcc atcgcaccaa acgggcaagc cagcatacag cttttacagc caatgcaacg
    18841 tgattgttca acgaaaatat gcccatgttc gcggcttatc gcgtcaacag ggcagacatt
    18901 cgcgcacggt gcatcttcac actgatgaca ggctactgcc gtggtccagc tgtggtcttt
    18961 aatgacacga atacgggaaa taaactcgtc tggtgacaac gcagcgcaat cctgattctc
    19021 ctgatgcgac actgcgcaag ccacttcaca ggtacggcaa ccgatacatt tcgtcgcatc
    19081 cgcaataata aaccggttca tgatcactcc tttgcactaa aacagcagag tgccagagag
    19141 cgcgtcccta ctgctttgat ccaacgaagg aaatgttaaa gttttggcac ttgtccaaag
    19201 ggttatgtaa tcgcgccctg gtcgtccctg acagtaaatc ccagctcatt agaaatagcc
    19261 tgcgcggttt cacgcagtgg tttcaggaga tttttctctc ccacctgttt cagacgtgat
    19321 gtcgaaagcg aaatcgacac ggcgtacggc acccgcccat gaatatcaaa caccggaaca
    19381 gcaatacagg agacgccgag ttcgttttct tctctgtcca tcgccgctcc actttcacga
    19441 atgtgcgcca gttcgtcgaa catcgcgggc agctcggtaa tggtattgcg ggttaacggc
    19501 tggatctcat gctgatggct ttcccagtat gacttcacgt agtccgggtg accaaacgcc
    19561 atgtagatct tgcccattgc ggaacagtag agcggcatat gctggcctat ataggcacgg
    19621 gttcgcagca tcccggttgt gggttccagc ttataaatca aaatagcgtg atcgtcttcg
    19681 cggctggaga agttaatggt ttcaccagtg gcgatgttca gtgcctcaag atgcggagcg
    19741 gcgatatgaa tgatattcag cgaagatagc gccttctgcc cgacggcaat aaatttggtg
    19801 gtcaggcgat aactccctgc ggcgggcgcg gtggtcacat agccgcagga ctgtaatccc
    19861 tgcaataagc gatggacggt actcttattt aaaccagcca gctccgaaag atgcgccaac
    19921 ggacaaccgt ttggatagtt gctcaaaatc tcaatcagca tcaacccacg aaacagactc
    19981 tggcttccgg ctggacgctc tttttcctgc gccatctcgt tctctttttt tcccatcact
    20041 tctttcccca ttttgtcgcg tcctgatggt agcgcaaagt gtgccgtagt tcacgatctc
    20101 gacagataat ttataaccac ttgattttta agttttttga aattcatcaa tcagattgct
    20161 ttgttaaaaa gtgatcgata tatttgaaat caagtttcgt atattgaaat tttaagccaa
    20221 aaaagcgatc aaaaaaacaa ggaagcctgg gatgaaagtg acatttgagc agttaaaagc
    20281 agcctttaat cgggtcttaa tttcacgcgg cgttgacagc gaaacggctg acgcctgtgc
    20341 agagatgttc gcccgcacca ccgaatccgg cgtttattct cacggcgtta atcgtttccc
    20401 tcgtttcatt caacaactgg aaaacggcga tatcattcct gatgcccaac ccaaacgtat
    20461 aaccagcctc ggcgcaattg aacagtggga cgcccagcgt tcgatcggta acctgacagc
    20521 gaaaaagatg atggatcgcg ccattgaact ggctgccgat cacggtattg gtctggtggc
    20581 actacgtaat gccaaccact ggatgtgcgg cggcagctac ggctggcagg cggcggaaaa
    20641 aggctacatt ggcatttgct ggaccaactc catcgccgta atgccaccgt ggggcgcaaa
    20701 agagtgtcgc atcggcacca acccgctgat cgtcgccatt ccttccacgc cgatcaccat
    20761 ggtcgatatg tcgatgtcga tgttctctta cggcatgtta gaagttaatc gcctggctgg
    20821 tcgtcagctc ccggtagatg gtggctttga tgatgagggc aatttgacca aagaacctgg
    20881 cgttatcgag aaaaatcgcc gcattttgcc gatgggctac tggaaaggtt cgggcatgtc
    20941 gattgtgctg gatatgatcg ctaccctcct ttctgacggc gcatcggttg ccgaagtcac
    21001 cgaggacaac agcgacgaat acggcatttc acaaattttt attgccattg aagtggacaa
    21061 gcttatcgac ggtcccaccc gcgatgccaa actgcaacgc attatggatt acgttaccag
    21121 tgccgagcgt gctgacgaaa atcaggccat tcgcttaccc ggccacgaat ttactaccct
    21181 gctggcagaa aaccgccgta acggtattac cgttgatgac agcgtgtggg caaaaatcca
    21241 ggcgttataa ggagataagc catgattttt ggacatatcg cgcagcctaa tccgtgccgt
    21301 ttgcccgccg ccattgaaaa ggcgctcgat tttctgcgca ccaccgactt caacgccctg
    21361 gatccgggcg ttgtcgaaat cgacggcaag aatatttatg cgcaaattat cgatttaacc
    21421 acacgcgaag cggtggaaaa ccgtccggaa gtgcatcgtc ggtatatcga tattcagttt
    21481 ctggcgtggg gtgaagagaa aattggcatt gccattgata cgggaaacaa taaagtcagc
    21541 gaatcactat tagagcagcg cgatattatt ttttatcacg atagtgaaca tgaatcattt
    21601 atagaaatga taccgggtag ttacgctatt ttcttcccgc aggatgtaca tcgcccggca
    21661 tgtaataaaa atgccactac ggcaatacgc aagatcgtgg ttaaagtggc cctcgctgct
    21721 ttataaaaaa tgattactgg agcacataat gaaaacgaat aatgccggtt atattatcgg
    21781 cgcgtatccc tgtgcacctt cttttcacca aagaagtgaa gaggaagaga aggatttctg
    21841 gcgacaatta tctgagactc cagacatttt gggtctggaa caaccttgcc tggaaaattt
    21901 tcaccctctt ggcgatcaat ggttactccg tcatacgcca gagagctgga aatttgtcgt
    21961 caccgcagtg atggaaacca tgcgtcgccg cagcgaaaac agcgggtttg gtctcgcctc
    22021 cagtgatgaa gaacagcgcc aggcctgcgt ggcgtactat cgccacctgt tcaataaaat
    22081 caacgcattg caggctaata aagtgctcgc actggcgctc caggctgcac cgttagcaac
    22141 gaatcctaat gttatgcaag cgacggacgc ttttgcccgc tcattgaaag aaatcgccag
    22201 ttgggactgg ccgtgcaagc tggtgctgga acactgcgac gccatgacat cttcttcccc
    22261 ccgaaaaggc tttttgcctt tagaaaatgt gctggaagtt attaccgatt atgacatcag
    22321 catctgtatc aactgggcgc gctctgccat tgaagggcgc aatacaacgc tgccgctgac
    22381 ccacacccaa atggcgaaac aagccggaaa actcggcgcg ttgatgttct ctggtacgac
    22441 gctaaacggg gcatacggcg aatggcagga tttacacgca ccgtttgcac cattctgcgc
    22501 agaaagcctg atgaccacag atcatgttcg cgagttattt aatgtagcag aatcgtcaac
    22561 attgcatttt gctggcatca agctactgga aataaatgcg acggctgatg tgcaccatcg
    22621 catcgaaata ttacgtaacg gcattcactc tctgaatgaa tctcgttaaa tagatccgct
    22681 tatatatcac tttgaatatc taattagccg ttttctgata attattacga atattaacaa
    22741 cattagcgca taaaaaatat tgcataacca gaaggactcg ttatgaaacg gatactcgaa
    22801 ggcattcttg cgatcatcat cgcaatactg tcttgtatta tttttattaa tatcattctt
    22861 cgatatggat tccacacaag tatattatcg attgatgaat tatcccgact tttatttgtc
    22921 tggttaacct ttattggcgc aatcgttgct tatatggaca acagccatgt gcaggttact
    22981 tttttagtcg aaaaactctc accggctaat caacaacgtg tttcgctgct aacccatacg
    23041 ctcattttat tgctgtgtct ggggctggcc tggggcgcta tagaaaaaac agcgcaagac
    23101 tggagcaact tatcgcccat tcttggcgtc cccgttggct taatgtacgc cgccgctatc
    23161 cccaccagtc tgattatcgc attgctggaa ttgcgtcact tataccggca gttcacaaat
    23221 acccccagcc gaaaccaaca aggagcctga cgatgacaat ccttatattt attgtcagtt
    23281 tgttaggggc tatcgcaatt ggtgttccca tcgcctgggc attattgttg tgcggcatct
    23341 cattgatgtt ctggatggat atctttgatg tgcaaattct ggcacaaacg ttggtaaatg
    23401 gcgcagacag cttctccctg ttagccatcc ccttctttgt actggcgggt gagatcatga
    23461 acgcgggcgg cctgtcgcaa cgtatcgtcg acttgccaat gaaactggta ggccacaggc
    23521 caggcggtct gggttacgtg ggcgtgctgg cagcgatgat catggcaagc ctgtccggtt
    23581 ctgcggttgc tgataccgca gctgtcgcgg cgctgctggt gccgatgatg cgccaggcca
    23641 actatccggt aaaccgcgcc gccgggctta tcggttccgg cgggattatt gcggccatta
    23701 tcccaccttc cataccactc attatcttcg gcgtctccag cggactctcc atcagtaagc
    23761 tgtttatggc gggcatcgca ccgggcatca tgatgggcgt cacgctgatg gttacctggt
    23821 ggtggcaggc aaaacgactg aatttacctt gtcagccgaa agcctcactg cgagaagtct
    23881 ggcaatcctt agtttccggt atttgggcgc tctttttacc gataattatt attggcggtt
    23941 tccgttcggg gttatttaca ccgaccgaag caggcgcggt tgccgccttc tacgctctgt
    24001 tcgtctcggt ggtggtctat cgcgagatga ccttctccac gctttatcat gtgctgatta
    24061 acgcggcaaa aaccacatcc gtggtgatgt tcctggtggc ctctgctgcg gtatctgcat
    24121 ggcttattac gatcgccgaa ttacccatga tggtatcgga gctattacaa ccgttggttg
    24181 attcgcctcg cttattattc atcgtcatta tgctcgctat tatggtgatc agtacggtca
    24241 tggacttaac gcctaccgta ttaattctta caccagtatt aatgccatta gtgaaagaag
    24301 cgggaataga tccggtctat ttcggcatca tgtttattat caactgttca atatcactga
    24361 ttacgcctcc agtcggtaat gttcttaacg tggtatgcgg cgtggcgaaa cttaaatttg
    24421 acgatgcggt aaaaggcgtt gcgccttacg tcatggtttt attcatgttg ttagcattat
    24481 ttatttttat accggagctc attaccgctc ctcttaaatg gatgagttaa aaggaaatca
    24541 taatgaaatt acgttctgta acctacgctt tattaattgc cggagtggcg acgttcagca
    24601 catcttctct ggcggcacaa tcattacgtt tcggttatga aacctcacaa accgattcac
    24661 aacatattgc ggcgaaaaaa tttaatgaat tactgcagga aaaaaccaaa ggcgaactga
    24721 aattaaaact gttcccggat agcacccttg gtaatgcgca ggcgatgatc agcggcgtgc
    24781 gtggcggcac tattgatatg gagatgtctg gctctaacaa ctttacggga ctctcgcccg
    24841 tcatcaacct gctcgatgtc ccgttcctgt tccgcgatac cgctcacgcg cataaaacgc
    24901 tcgacggcaa agtcggtgat gacctgaaag tctcccttga aggtaaaggg ctgaaagtgc
    24961 tggcttactg ggaaaacggc tggcgcgatg tcaccaactc acgccagcca gttaaaacac
    25021 ctgccgacct gaaaggacta aaaatccgca ccaacaacag cccgatgaat atcgccgcat
    25081 ttaaagtttt tggcgctaac ccgatcccga tgccgtttgc cgaagtctat accgggctgg
    25141 aaacccgcac tatcgacgct caggaacacc cgatcaacgt cgtctggtca gcaaaatttt
    25201 tcgaagtgca gaagtacctt tctctgaccc atcacgccta ttccccactt ctggtggtga
    25261 tcaacaaagc gaagtttgat ggcttaaccc cggagttcca gcaggcactg atctcatctg
    25321 cgcaggaagc gggtagctat cagcgcaaac tggtcgccga agatcagcaa aaaatcatcg
    25381 acggtatgaa agaagcgggc gtggaagtca tcaccgatct cgaccgcaaa gcctttagcg
    25441 atgcgctggg tacccaggtc cgtgacatgt ttgttaaaga tgttccccag ggtgctgatc
    25501 tgctgaaagc cgtggatgag gtgcaataaa ccatgacgca atactggctg gggttagatt
    25561 gtggcggtag ctggctgaaa gccgggctgt atgaccgaga aggccgggag gcgggcgtgc
    25621 agcgcctgcc gctgtgcgca ttaagtccac agccaggctg ggcagagcgc gacatggcag
    25681 aactgtggca atgttgcact gctgtcattc gctccctgct tacccattct ggcgtcagcg
    25741 gggaacaaat tgtcggtatc ggcatctccg cgcagggaaa gggcttattt ctacttgata
    25801 aaaacgacaa accgctcggt aacgccattt tgtcctcgga tcgccgggcg atggaaatcg
    25861 ttcgtcgctg gcaggaagat ggcatcccgg aaaaactcta tccgctgacc cgacaaacct
    25921 tatggaccgg gcatccggtg tcgctgttac gctggctgaa agagcacgaa ccagaacgct
    25981 acgcgcaaat tggctgcgtg atgatgacgc acgactacct gcgctggtgt ttaaccggcg
    26041 tcaaaggttg cgaagagagc aatatttctg agtccaatct ctacaacatg agtcgcgggg
    26101 aatatgaccc gtgcctaacc gactggctgg ggatcgctga aatcaatcac gccctgccgc
    26161 ctgttgtcgg atctgccgaa atctgcgggg aaatcaccgc tcagacagcc gtactgactg
    26221 gtctgaaagc gggtaccccc gttgtcggcg gcctgtttga tgtggtttcc accgcactct
    26281 gcgccgggct cgaagacgaa ttcaccctca atgcggtgat ggggacctgg gcggtgacca
    26341 gcggcataac ccacggttta cgtgacggtg aagcgcatcc gtatgtctat ggtcgctacg
    26401 ttaacgatgg tcaatttatc gttcacgaag ccagccccac ctcttccggc aatctcgaat
    26461 ggtttaccgc acagtgggga gaaatctcat ttgctgagat taatcaggcc gtagccagtt
    26521 tgccgaaagc cggtggcgct ctctttttcc tgccgttcct gtacggcagc aacgccggac
    26581 tcgaaatgac cagcggtttc tacgggatgc aggccattca cacccgtgca cacctcttac
    26641 aggctatcta tgaaggggtg gtgttcagcc atatgaccca tctcaaccgg atgcgcgaac
    26701 gttttactga tgtgcacacc ctgcgcgtca ctggcggccc ggcgcactcc gatgtctgga
    26761 tgcaaatgct ggctgacgtc agcggtctgc gtatcgagct gccgcaggtg gaagaaaccg
    26821 gctgctttgg tgcggcactt gccgcccgcg tcggtaccag ggtttatcgc gatttcagcg
    26881 aagcccaacg tgacttacag cacccggtac gcaccctgct gccggatatg gccgcccatc
    26941 agctttacca acaaaaatac caacgctatc aacatctcat tgccgcactt cagggttatc
    27001 acgcccgcat caaggagcac acattatgag tcgaccactt ctgcaactgg ccctcgacca
    27061 ctcatcactt gaagccgcgc agcgcgacgt gacgctgtta aaagacagcg tcgatattgt
    27121 cgaagcaggc accattctct gtttaaacga agggcttggc gcagtgaaag ccttgcgcga
    27181 acagtgcccg gacaaaatca tcgttgccga ctggaaggtc gccgacgcgg gtgaaacgct
    27241 cgcgcaacag gcatttggcg caggcgctaa ctggatgacc atcatctgcg ccgcgccgct
    27301 cgccacggtg gaaaaaggcc acgcgatggc acagaactgc ggcggtgaaa ttcagatcga
    27361 gctattcggc aactggacgc tggacgatgc ccgtgactgg catcgtattg gtgtacgaca
    27421 ggcgatttat catcgtggtc gtgacgcgca ggccagcggg caacagtggg gcgaggccga
    27481 tctggcacgc atgaaggcgc tttccgatat cggccttgag ctttccatta ccggcgggat
    27541 tacccctgct gacctgccgc tgtttaaaga gatccgcgtg aaagcgttta ttgccggacg
    27601 gtcgctggca ggcgcagcaa atccggcgca agtggccgct gattttcatg cgcaaatcga
    27661 ctccatctgg ggaggcaagc gtgcgtaatc atccgttagg tatttatgaa aaagcgctgg
    27721 cgaaagatct ctcctggccg gagcggctgg tgctggcaaa aagctgtggt tttgattttg
    27781 tcgaaatgtc ggtggatgaa accgacgaac ggttgtcacg tcttgactgg agcgccgcac
    27841 aacgtgcttc gctggtcact gcgatgctcg aaacgggtgt tgctattccg tcaatgtgcc
    27901 tgtccgcaca tcgtcgtttt ccttttggta gccgggacga cgccgtgcgc cagcgggcgc
    27961 gggagattat gagtaaagcg attcgcctgg cacgcgatct cggcattcgt actattcaac
    28021 tggcaggtta cgacgtctat tacgaagatc atgacgaagg cacccagcaa cggtttgctg
    28081 aagggctggc gtgggcggtt gaacaggcag cggcatcaca agtcatgctg gcggtggaga
    28141 ttatggacac cgcgtttatg aactctatca gcaaatggaa aaagtgggac gaaatgcttg
    28201 cgtcaccgtg gttcaccgtt tacccggacg tcggcaatct cagcgcctgg ggcaatgatg
    28261 ttcccgccga actgaaactg ggcatcgacc gtatcgccgc catccacctg aaagacactc
    28321 aacccgttac cgaacatagc cccggacagt tccgcgatgt gccgtttggc gaaggctgtg
    28381 tcgattttgt tggcatcttc aaaacgctgc atgagctgaa ctatcgcggt tctttcctga
    28441 ttgagatgtg gaccgaaaaa gccaaagagc cggtgctgga gattattcag gcgcggcgct
    28501 ggattgaagc gcgtatgcag gaggccggat ttatatgtta gagcaactga aagctgacgt
    28561 gctggcggca aacctggcgc ttcccgttca tcatctggtg acgttcacct ggggcaatgt
    28621 cagcgcgata gacgaaacgc ggcaatggat ggtgattaag ccttccggcg ttgagtatga
    28681 ggtaatgacc gccgacgata tggtggtggt tgagatagcc agcggcaagg tggtggaagg
    28741 cagcaaaaag ccctcttccg acacgccaac gcatctggcg ctttaccgtc gctttgcgga
    28801 gattggcggc atagtgcata cccactcgcg ccacgccacc atctggtcgc aggccggact
    28861 tgatctcccc gcctggggca ctactcacgc cgattatttt tacggagcca tcccctgcac
    28921 gcgcctgatg accgcagaag agatcaacgg tgagtatgaa taccagaccg gcgaagtgat
    28981 cattaaaacc ttcgaagagc gtgggttgaa cccggcacaa atcccggcgg tactggtgca
    29041 ttctcacggc ccgttcgcct ggggaaaaaa tgccgccgat gcggtgcata acgccgtggt
    29101 actggaagag tgcgcctata tgggtctgtt ctcgcgccag cttgcgccac agctccctgc
    29161 gatgcaaaac gaactgctgg ataagcacta cctgcgtaag catggggcca atgcctatta
    29221 cgggcagtaa tccctcacgc cggggcttca tcgccccggc actacgaatt gatatgttcc
    29281 ttgctgtaac gccgcttcca cgctgctggc gttaagccgg tgtgtttgcg aaaaatctgc
    29341 cggaaatagc cgacgtcatt aaacccgcac aacgccgcca cttccgtgag cgatcgcgct
    29401 tcgctaatta acagcttttc ggcttcgcgc acccgctggc ggtggattgc ttctgttaac
    29461 gtcagatgaa acacccgccg atagacgcgc ccaagataat cggcattgca gtacagctcg
    29521 cgggctaaaa gcgccgtgga aagcgggcgg tgatattgcg tgcgaatcag tttctgcgct
    29581 ttccaggcaa gggtggtgcc tgcaccatcg gcctgttcat caagacgcgc gtcacgggtg
    29641 agctgctgca aaatcagcag cacaataaac tccagcgccg gagtgcgttg atgcttttcc
    29701 tgttcgctta agaactggcg aaacaaggcc accagcacct gcggatcggc aaccttagtt
    29761 tgttgcggca cgctaagatg agtgagccag cgcggatcgt tgtccggcgc tttaacctca
    29821 aaatgcagcc agtaaaattt gagatcggcg ggaaaatcct ccaccccaac atgctgtcgg
    29881 ttcggccaga gtaataaact ctctcccgca tcgaccagaa atatccgttc atcttcctga
    29941 atcgttaatc gacctttttc gacgaagata atttcccatg actccagccg ccttgcagga
    30001 tgcctcccta cgccacggga aataaataat ccaccatttt gcactttaat cggtaacgtc
    30061 atggataatt cgagcattga tatgtaattt cccgcttatt cattaatgat taaacacatt
    30121 accttttgat tattaatcaa aaacattaat ttcacctgat ccatttcaca cttttaaatt
    30181 caggtcggaa tcgtcacctt tttttactct tttctcgcct tgttgatatt cccgttcacg
    30241 gcagaattaa tcaggtcatt gcaataaaac taaaaattgc tccctattca cgaggaatat
    30301 ctatgacctc tacaccgatt accaccgctg atatcgctaa aggtaaaatt gacgatgcgt
    30361 tatctgtacg ggaaaaaata ggctacggcc tgggtgacgc aggcggcacc gtaataactt
    30421 gcctgatcat gaactttctc acctttttct acaccgacgt ttttggctta actccggcgc
    30481 tggttggcac gctgtttatt gcgctacgcg tgtttgatgc catctccgac ccggtgatgg
    30541 gcgtcattgc cgaccggacg caaagtcgct gggggcgctt tcgtccgtgg cagttatgga
    30601 ttgccattcc catcggcatt atcggcatcc tgacattcac cgtgccagat gccagcatgg
    30661 gagtaaaaat cgcctgggcg ttcggtactt acctgctcct ttcagtcggt tatacagcca
    30721 tcaacgtacc gtactgcgcg ctgatcaaca ccatgaccac ccgccacaat gaagtgatct
    30781 cctgccagtc ctggcgattc gttctctgcg gcgtagcggg atttctggtt tcggtaggct
    30841 taccgtggat ggtagatctc ttcggtcagg gcaacgctgc acgcggctat caacttggcg
    30901 tcggcgtatt gtgcgccatt gccgtggtga tgttcctgtg ctgtttcttc tgggttcgtg
    30961 aacgggtgcc actctccaca atggggaaat ttaccctgcg cgaacatctt gccgggctgc
    31021 ggaacaacga ccaactgctg ctgatgctgg tcatgtcttt cctgctgatt aacgtcttta
    31081 atattcgcgg cggtgggtat atgtacttca ttacctacgt cttacaaggc agtacgggct
    31141 acacgtcgct gttcttcacc atggtcacct tcgcctccat tatcggctcg gtgattgtca
    31201 gcccattaac gcggcgtttc gataccgtca aaatttacta ctacaccaac ctgctcctcg
    31261 ctgcactggc ggtgttgatg tggttcctgc cctccagccc ggcttatcaa acgctgtggc
    31321 tggtggtgat cctcggtaat ggcgtgattc ttggcttcac attgccactg cacttctcat
    31381 tgatggcctt tgccgatgac tacggcgagt ggaaaacccg cgtacgttct tccggcatga
    31441 acttcgcctt caatctgttt ttcatcaagc tggcctgggc ctccagcgcc gggatcatca
    31501 gcctgctgtt tatttttgtc gcctaccagc caggcgtgga aaaccagacc gccagttcgc
    31561 ttggcgggat cgcggcgatg gaaacattgc tgcctgcgct gttccacctg ctgctggcga
    31621 tggcgatccg cttttgcaaa ctcaataacc ctatgatgtc acgcattgct agcgacctgc
    31681 gtcagcgtca tgtacagcct taaggagcac aagatgaaca tttcggaagt cgatctgcat
    31741 aaactgacgg tcagcgatcc gttcctcggt cagtaccaac aactggtccg cgacgtggtg
    31801 attccttatc agtgggatgc cttgaacgat cgtatcccag aagcggaacc cagccatgcg
    31861 attgaaaact ttcgcattgc cgccggactt caggagggtg aattttacgg gatggtgttt
    31921 caggacagcg acgtcgccaa atggctggaa gcggtagcct ggtcgctgtg ccagaagccg
    31981 gacgccgaac tggaaaaaac cgccgacgag gtgattgaac tgatcgcttc cgcccagtgc
    32041 gaagatggct atctcaatac ttactttacg gtaaaagcgc ccgaagaacg ctggagcaat
    32101 ctggcggagt gtcatgaact ttactgcgcc ggtcatctga ttgaagccgg agtcgccttc
    32161 ttccaggcta cgggcaagcg gcgcttgctg gaagtggttt gccgtctgac cgatcatatc
    32221 gacagcgtat ttggtccaga tgaaagtaag ttacatggtt atcctggtca cccggaaatt
    32281 gaactggcac taatgcgcct gtatgaagtg accgaagagc cgcgctacct ggcgctgacg
    32341 aactattttg tcgaacagcg tggtgcgcaa ccgcactatt acgaccagga atatgaaaag
    32401 cgcgggcaga cctcgcactg gcacacctac ggcccggcgt ggatggtgaa agacaaagcc
    32461 tacagccagg cacatttgcc catcgcacag cagcaaaccg ccattggtca cgcggtacgt
    32521 tttgtctacc tgatgaccgg cgtcgcgcat ctcgcgcgtt taagtcacga tgaaagcaag
    32581 cgtcaggact gcctgcggct gtggaacaat atggcccagc gtcagttata tattaccggc
    32641 ggcattggct cacagagcag cggtgaagcg ttcagcagcg attacgatct gccgaatgac
    32701 acggtatacg ctgaaagttg cgcctccatc ggcctgatga tgtttgcccg acgaatgctg
    32761 gaaatggaag gcgacagtca atatgccgat gtgatggagc gcgcactgta caacaccgtg
    32821 ctcggcggca tggcgctgga tggcaaacat ttcttctatg tgaatccgct ggaagtacat
    32881 ccaaaatcgc tgaaattcaa ccatatctac gatcacgtta agccgatccg ccagcgttgg
    32941 tttggctgcg cttgttgtcc gccaaatatc gcccgcgtgc taacctcgat tggtcattat
    33001 ctctacacgc cgcgtgaaga tgcgttgtat atcaacatct acgcaggaaa cagcatggag
    33061 gtgccggtag aaaatggcac gctgcgcctg cgggttagcg gaaactatcc gtggcaggaa
    33121 caggtgacga ttgcggttga atcaccccag ccggtgcgtc atacgctggc tttacgtcta
    33181 ccggactggt gcatacagcc gcagatcata ttgaatgggg aagaggtcga gcaggatatt
    33241 cgtaaagggt atttgcacat tacccgtgaa tggcaggagg gcgacacgct gaatctgact
    33301 ttgccaatgc cggtacgtcg cgtttacggt aacccgctgg tgcgtcacgt cgccggaaaa
    33361 gtggcgattc agcgcggccc gctggtgtat tgtctggaac aggtcgacaa cggcgagtca
    33421 ctgcataatc tgtggctgcc cgccgatgcg ccatttacga catttgaagg taatggattg
    33481 ttccgccata agatcttaat ccaggcaccg ggttaccggt atgaacagag caatccagag
    33541 cagcaaccgc tgtggcatta cgacagcgcg ccagccaaac gccagccgca aattctgacg
    33601 tttatcccgt ggtttagctg ggccaaccgg ggtgaaggcg aaatgcggat ctgggtgaat
    33661 gaggaaacca gtgccatccg taggtaggat aaggcgctcg cgccgcatcc aacgcatggt
    33721 gcacattgcc ggatgcggcg tgaacgcttt atccgaccta caaaagcatg caaattcaat
    33781 atattgcatg agctatgtag gcatgataag acgcgaaagc gtcgcatcag gcaatgaata
    33841 cccgatgcga ccagcttctt acatcagaac agccccaacg gtttatccga gtagctcacc
    33901 agcaggcact tggtttgctg gtaatgctca agcatcattt tgtgggtttc acggccaatg
    33961 cctgattgtt tgtagccgcc aaacgccgca tgtgccgggt aagcgtgata acagttggtc
    34021 cacacgcgcc ctgcctgaat gccgcgcccc atcttatagg ccagattacc gttgcggctc
    34081 cagacgcccg cgcccagacc atattgcgta tcgttcgcca gctccagcgc ttcttccatc
    34141 gttttgaagg tggttaccgc cagcaccggg ccaaaaatct cctcctggaa cacgcgcata
    34201 ttgttctgac caaacagaat cgtcggttcg aggtagtagc cgtctttcag ttcgccttcc
    34261 agcagcttac gtcgcccgcc ggtgagcaca tcagcgccct cttttttacc gatatcaatg
    34321 tagttgagga tggtttccag ttgcccgtaa gaaacctgcg cgcccatttg cgtcacgctg
    34381 tcgagcgggt taccgctgcg aatgctttcg acacggcgga tagcgcgttc cataaagcgt
    34441 tcgtagatag actcctgcac taaagcacgg cttggacagg tgcaaacttc gccctggtta
    34501 aaggcaaaca gtgcaaagcc ttccagcgct ttatcgaaaa aggcatcttc ttcatccatc
    34561 acatcagcaa agaagatatt tggcgatttg ccgcccagct ccagcgtcac cggaataatg
    34621 ttttgcgtgg cgtattgcat aatttgttgg cccacttccg ttgagccggt aaacgccact
    34681 ttggcgatgc gtttcgaggt cgccagatat tcgccaattt ccccacctgc gccattgacc
    34741 acgttcacca cccctggcgg cagtaaatca ccgacgattt ccattagcag cagtacagaa
    34801 agcggagtaa gacgtgcggg tttcagcacc acacagttgc ccgccgccag cgcgggggcc
    34861 attttccagc tcgccatcag cagcgggaag ttccacggga taatctgccc caccacgcct
    34921 aacggttcat ggaaatgata ggccacggtt tcgctatcca cttcactgat cccaccttcc
    34981 tgcgcccgaa tacacgaggc gaaatagcga aaatgatcaa tcgccagcgg cacgtcggca
    35041 gcactggttt cgcgaatggg tttgccgtta tcccaggttt ctgccgtcgc taaaagttca
    35101 aggttttgtt ccattcgatc ggcaatctta aacagaatcg ccgcgcgatc ctgcaccgag
    35161 gtgtgcgccc atttatcttt cactttatgc gcagcatcca gcgccagatc gatgtctcgt
    35221 ttgcccgaag acgccacttc gcacagtagc tgcccggtca ccggcgtcag gttctggtaa
    35281 tactcgccat cggcaggcgc tacccattcg ccaccgataa agttgtcgta gcgggctttt
    35341 aatttgaggg ggaaaccata ctcgccgggc ttaatctgtg ctgaaggggg attattggtc
    35401 atgatcgtct ccttgcggtg tgaggtataa caagggtaga cgtgactggc gaaatcttcg
    35461 ccagtcggta acagctttac gacggctatc acgaatttac gggcaaaagc tacagcgggt
    35521 agtgtgcgac gtacactgct tgctggttat taattctttt ctcttgcgcg aatccttctt
    35581 taacaattgt ccgtaaatca gctcgagccg tattatcaga gacgcccaag ctcgcgctaa
    35641 tttcagcaac tgtgtactct ttccccggat tggcgagcat cacattcagg agcgttacct
    35701 ggcgcggatt caggcgttta agcacaccag agctaaacag cacactatcg agttttgcgc
    35761 ttcgttgtgt aatttcatcg atatgctgct gccagttttg cagagcacgt ttaatgacac
    35821 ccgcctgata ttcaaggaaa taagtcagat ccataccatc tgattcagtg tactggtagc
    35881 tggcggcata tttgaccggt gcagcatgaa gcaaacggct gatggaaata tatttaaaga
    35941 catcgtagcc cgatttcagc atataccagt aaaacagcgc ccgactggtg cgcccgttgc
    36001 catcccgaaa cggatgttca tgggccagca taaaatgcag aatgcaggca cggaccaacg
    36061 gatgaatata cccttcatgg ctgtttaacc actggcaaac tttttccagc cgttccggta
    36121 acaatgccgc agcgggcggt tgatgcacta tattgccatc atagtcggcg atcacaacat
    36181 catctgtttc acgaaattct cccggacgat atttcgcgtc attgattcca cccataccaa
    36241 tggcatgtaa ctggcgaata agcgcaggtg tcagcggttc tgcgagtaag tgcggaattt
    36301 ccgccatcag ccgggcattt cccgcaatca tatgctcgtc ttcagtgcgt ggcgaccgcc
    36361 ctgtttccag catttttctc gccaccagcg ttgtagtatt cgcaccttcc agctgggagc
    36421 tggtgatcgg ctcttccagg cgtaactggc ttaactcggc tccggccccg cgtaaccgtt
    36481 cagtctgatc tttcagcgcc agcgcggtag cacgtttgtc gacaagctcg cacgcttctg
    36541 caatcaccgg ggtaatgttg aatccggcct gttcacccgc ttcattgcaa taattaattc
    36601 gttggatcgc cgcgttgcgc gccagacggg taagcgtcca cgccacatcg acgttttctc
    36661 cttttttgat gcggtactgc aactcatcaa aaggcagata acgtcctttt tcatcggtaa
    36721 cccggttaaa gcgcaggtgg gccaggagtt cctcacccga taagtgtgat aaaggaataa
    36781 gtccgggagg tgatttgata gccatgtgct tatctcaaaa aagcgcaata ttgagatagt
    36841 gtatagcagg aaagagaaac tatctcaaaa aaagcaagtt ttgagatagt tgaaaaagcg
    36901 gctgacaact cgccagccgt tgtgggaatg atgattacat cgctgcgcga taaatcgcca
    36961 caatttcttc gtgagttgcc tggatcgggt tagtaaagcc gcaggcatct ttcagggcat
    37021 tagtcgccag aaccgcgaaa tcttcttctt tcacgttcag gtcgcgtagg cctgccggga
    37081 tatccacttt cttcgccagt tcacggatgg cgttaatgca ggcttcagca ccttccgcgt
    37141 cgtttttacc tgtcacgttc acgcccattg cagcggcaca atcacgcaga cgtgcagcgg
    37201 cgactttgct gttgaatacc tgaacatgcg gcagcaaaac ggcgttacat acaccgtgtg
    37261 gcaggttgta gaaaccgccc agctggtgcg ccatcgcatg aacataaccc agagaagcat
    37321 tattgaacgc cataccggcg aggaactggg cataagccat tgcttcacgc gctttcgcat
    37381 tactgccatc ttcaacggct aacggcaggt tttcggcaat catggtcacg gctttcagtg
    37441 cacaagcgtc agtgatcggc gtggcggcaa tagaaacata cgcttcgata gcgtgcgtta
    37501 aggcatccat acccgttgcg gcggtcagtg acttcggcat accgatcatc agagaggagt
    37561 cattgacaga aagcagcgga gtgacatgtt tatccacaat cgccattttg atgtgacgcg
    37621 cttcgtcagt gatgatgcaa aaacgggtca tttcagaggc cgtacccgcc gtggtgttga
    37681 tggcgatcat cggcagctgc ggttttgcag agcggtcaac gccttcataa tcgcggatgt
    37741 caccgccgtt ggctgcaacc agcgcaatac cttttgcgca gtcgtgtgga gaaccaccgc
    37801 ctaaggaaat cacgctatcg caattatttt ctttaagtaa tttcaaacct gcagcgacgt
    37861 tttccgtggt gggattaggt tgggtgccat cataaataac gctaaaaata ttgcgttctt
    37921 ccagtgcttt ttgcacatca cccgccatac ccaatttcgt taacatattg tcggtgacaa
    37981 ttaaggtacg ggtaaatcca taatctgcca tcatattcat tgcatcattc aatgaatcag
    38041 caccaataac attcacggaa ggaataaaaa aggttgaagc tgccataaca cactcctgaa
    38101 agtgtaaaaa agggcgggca gcttactgag aattttcatt tgaaaatatg atcaatatta
    38161 ccgtttatta aaatattttt aataaaaagc acgttacatt catcaaataa cgtgccttct
    38221 taacattaat aagaaatttt gtattaattc atatttatta tgaattaatc atttccttat
    38281 ttttccggaa ataataatgc gtcgcgcaat aaatgatcat ttccacgacg acgcgtaaag
    38341 ccaatgcggt caaaatattc cagaatctga attgccagct tgcggcctac gcctaagcga
    38401 tcgcggaaat ccgccgcgca ggttgaacca cattcctgat cgagatcgcg gatcatattg
    38461 gcaaattcga caatccgatc gttacggtaa taacgatctt tgacgatcgc agtaattatc
    38521 ccctgttggg ccgcctggcg tagcgtcagg cgcattgcct gctcgtcggt tcccgtctct
    38581 tttgccaggt cacgcaccca ccatggctcg tcaccaaaca gcggctctgc tttttgccag
    38641 atggcctgct gctcttcgct gaagcccgct ttatgatccg gcagatgcag ccagccgtga
    38701 tggctgtgga tgtcgccgct ttcgcgcatc ttttcaatca gcaacagtac cagcgcttca
    38761 tcttccattg gcaacgccat acgtcgcaga cgttcgcgcc caggaccagg ttcatcgcga
    38821 tgttgctcat gataagtcgc taatgtgtcg agaattttcc gctgccagcg ggcggcaact
    38881 ggcgcattca acaagctgta accagcctga atatagccag gctgttgcag cagttcgcgc
    38941 atcccttcgc cgttgagctg ccgtgcccag gcgaaatccg caaggttaac cgcgccgcgt
    39001 tccagatgaa cagataacgc atcggcatcg ctctgcgccc gtgcaagaga cgccagccat
    39061 tgcagatatt ccggcttacg cttaccgcga cgcggcgggt taagcatcac cacacgcgcc
    39121 cccgccagcg tgttgcgggc cgagatatcg cgcagcacta tgcgatcgtt atccgccagc
    39181 cacagcggcg tgtcgaacac cagctcggca aggttatctt ccagtagcga aacacgtccc
    39241 gtaacgtggc tggcggcgtg gtgaatatgc agcggctgcc actgggtcag cggtgtatgg
    39301 gtttgaagct cgacaatcac ccgtgtgaac ggctccggcg gcacatcggc aagcagccag
    39361 tcgccacggt taatctgctc tttttccgca tcacccgcga tgttaagcgc gatacgctgc
    39421 ccggcatggg cagtttctgt tggctgattt tgcgcatgca gcgcacgcac gcgcatcggt
    39481 ttatttacac cagtcagcca gagtgaatcg cctactttca cttccccgct taacgccgta
    39541 ccggtgacga ccagcccggc accttttacg gtaaatgcgc ggtcgatcgc gaggcggaaa
    39601 ctatgttggc tggcgtgttc acgttctggt aactgaagca gatgctcgcg cagggcatca
    39661 attccccgac cttcggttgc tgcggtgata aacagttttg cctcagcaaa accgtattcc
    39721 cgcagcacct cctttacctg gcgttcaacc tcatcaacac gcgcttcgtc cacgcgatcg
    39781 gctttggtca gcgccactgt cagcatcggg ttaccggtca gctgcaaaat cgccagatgc
    39841 tcacgggtct gtgccatcac accgtcatcg cacgccacca ccaacagcgc gtgatcgata
    39901 ccaccaacgc ccgccagcat gttggaaaga aacttttcat gaccgggtac gtcgataaaa
    39961 ccaggcacgc gaccatccgg ctgcggccag taggcatagc cgagatcgat ggtcatgccg
    40021 cgcttttttt cttccggcag acggtcggca tttacgcccg taatcgcctg caacaaggtt
    40081 gttttgccgt ggtcaacgtg tccggcagtc gtaataatca tttcaacaac atctccaaaa
    40141 accgttgctc atcttcaagg cagcgtaaat ccagccacaa tcgtccgtca taaatacgac
    40201 caatcaccgg cactggcaat tcacgccagc gggcggctaa tgactcaagg tggctaccgc
    40261 gtccatcatg gggggtaaac gttaatgccg cgctcggcag gcgatcaacc ggcagcgaac
    40321 cactgccgat ctgcgaaaga catggcataa cctgtaccgc aaactccgcg ccgtaatgtg
    40381 cggcaaggag agcctgtaaa cgttgtgcct ggatttgaat gacctctgcg ctgcgggtaa
    40441 gcaggcgcag ggtcggtaat ttttcactca gagcttcagg gtgtaaataa agacgcaacg
    40501 tggcttccag cgccgcgagg gtcattttat ccgcgcgtaa tgcacgcttc agcgggtggc
    40561 tttgcaggcg ggcgatcatt tcttttttac caacaataat tcctgcctgc ggcccgccta
    40621 acagcttgtc gccggagaag ctcaccagac tgacgcccgc cgcaatcaac tcctgcggca
    40681 ttggctcttt cggcaaaccg tactggctaa gatcgaccag cgagccactg cctaaatcag
    40741 tcaccactgg aacatccagt tctttgccga gcgccaccag ttccgcttca tctatcgctt
    40801 tggtgaaccc ctgaatgctg tagttactgg tatgtacttt catcaacagt gcggtatttt
    40861 cattcaccgc ctgacgataa tcattcgcgt gcgtgcggtt ggtggtccct acttcgtgta
    40921 gggtgcatcc tgcctgacgc ataacatcgg gaatacgaaa cgcgccgcca atctccacca
    40981 gttcgccgcg agaaaccacc acctctttcc cgctggcagt ggccgccaac atcaataaca
    41041 ccgccgccgc attgttatta acgatacagg catcttccgc ccccgtaata cggcacagca
    41101 gctgcgccag cgcccgatcg cgatgtccac gtccggcgtc gtccagatcg tactcgaggg
    41161 tcactggcga acgcatagcc ttcgtaacgg cttccaccgc ggcttccgcc tgtaaagctc
    41221 gcccaaggtt ggtatgcagc acggttcccg tcaggttgat caccggacgc agcgcgcttt
    41281 gcgcctcttt cgtcaaccgg gcatcgactt cttgcgccca gttttcacac cacgcgggca
    41341 gcgtctggct gtcacgaatc acttctcgcg cttcgtcaag catctgacgc agcaattcca
    41401 ccacgcgggt gtgaccataa gtatcacgca aagaaaggaa ggagctatcg cgcaataagc
    41461 gatcaatagc cggaagttga ctatagaggg aacgcgtttc ggttgtcata ggaaacctgg
    41521 ctgatcaagg ccctctcaca cggagaaggg cgtttaacat aaccacggat tgtaacgtga
    41581 gatgggtcag gaggacatat cgcgcatcaa gcctttggcg gttcggtgcg agcaaaactt
    41641 tcgcggctaa acaggttttc gaccagtttg actaagtgtg ggcggtcgac acaccagcct
    41701 ggcgcaacgc ggcggaaatt gagatatccg accgcacagg caatggcgat agtcgccaga
    41761 ttgaccgtat cggttttgag cgtgccatcg accagatatc cttccagcac atccagactg
    41821 cggttgattt tctcacgctg acgtaacaat tcatcttcag actgctgcgc cgccggacgc
    41881 gcctgttcac gcaccgatac cagcccggca tccataatgc catccgccag cgcctcaatt
    41941 ttgcgcaccc gcaacgactc cagcggatca cgcggcaaca tcgccggagc aacattcatt
    42001 aattcaatat attcagcgat gatcggcgaa tcaaaccagc attcgccctc ttcggtcacc
    42061 agcaccggca cttttcctaa cgggttaaat tgcgccacgc cgttgtccgc gttatagggc
    42121 agttcattaa taaattcgaa cgttatgccc ttttctaaca acagaataga aagtttgcgt
    42181 acaaacgggc tggtgtagct accgacgagt ttcatgccga gtcctttgtg cgaggaaaaa
    42241 tatcagtatg gctcaggctc gcgcaaaaca caggtgatac aagtctcaat gatccaaata
    42301 aagataatgc atccaactgg tcattcttag cagcactttc cgcatcaccg aaacatggct
    42361 gaaatggtcg gagtaaactg ccacctgggc gtagatgccg tcgggtaagg catcgatatc
    42421 agcgttaggg tccagctcaa tggttcccag cacaccgtcc gtgccgggca cgaccgttaa
    42481 tgattgcaat accccctgcg cctgataaga accgcctggc acgacaggta aaatactggt
    42541 cagtttgccg tgaaacacct gcccaggtag cgcgttaaac accacttccg catcatcgcc
    42601 gggtttcaga cgtaacagcg agttttgccg aaattgggcg acaatttgcc gtttttgctc
    42661 ggggatgaag accatcaccg gacgcagcgg caaggcagcg gcgtatgtac ctgggcggat
    42721 cagtacctga gtgacgtagc cattgctcgg tgcgcgaatg acggtctgct caaggttata
    42781 ttttgcttca gtaagttgcg ctcttaagct cacaatctgc gattgctcgc cgttaaccat
    42841 actgtcgagc tggctctgga tctgcgcctg ctccgccacc gagcctttca ccagcgcatc
    42901 ctgcgcgagg aaattttgcc gcgcatcgtc gatgtcacgt tccgagaacg gattcaccgc
    42961 cgcctggctg cctttcagat aacgttgata atttttaaac agacggtcgc gctccgctga
    43021 aacctgggtg gtgttggcct gcgcttcagt gagttgcgcg cgcagcgtct ttatattatg
    43081 cgtcgccgtc atcaggtctg cctgaagtct gtcaactcgc gcctggtaac gaaccggctc
    43141 gagcttaaaa agcacctcgc ccttctgaat aagctgatta tttttgtcgg tgacttcagt
    43201 aacaattccc gtcacctgtg gcgtgatggg gatcgctatc actgcctttt gcgcggtaaa
    43261 agtgtaaggg tggttgtagt tcatcaacaa gatcaaacca ctcaccagaa acacgcctcc
    43321 cagcgccgcc gtcgccagcg tccactgatt taccggaatg cggaagattt taaagaccgc
    43381 ccacgccagc gccacgtaag ttaaaacaat caatagatcc atatttagat ctccggaaac
    43441 gtggaatagt cagtcttttt ctcggcggcg agttgatgct ccagccggga aattcggtca
    43501 gaaagtgcgg cgatttccgg gtcagtcgct ttctcttgcg acgcaacatg tgactgcatg
    43561 ccccagccgc gctccggttg atagagcgtc gcccagatcc acaggaacgg ccagataaca
    43621 tgtagagtaa acaggctcac ccagcccgcc gtatgaatag cgtcggcatg gggatggttg
    43681 cgctttttgg caatcagata agggatgtca tgtatcgcga tgattccata aaaaatcacc
    43741 agaaagacga agatcagcac tcccaacgcg aaatagttta gaaacatatc tgcctcggat
    43801 tcacgtttat cagtgttgtt ttttggctgg cagccagaag ggagtcaggc tgatattttg
    43861 acaataatcc gggttcgcga ttctcgccat aacaccaaag aataatttta agaggtgatg
    43921 agttgcttag ttacataacg atttcatgac gaaggcataa catgctgtag atcacatcag
    43981 gtgaacgccg taagaaaata tcttgtgatt cagatcacaa agattcaaca aaccatcaaa
    44041 acaaaaatgt gacattactc acatttaaat gccattttta gcgaaaatcg ccgccttgtt
    44101 gcttttttac acaagcattt tgtgatgagc atcacgtcaa ttacctctct accccctaca
    44161 tttatgtgac tgatatcaca caaaaggccg ccgactggac agttaaccga ttcagtgcca
    44221 gatttcgcag tatctacaag gtccggctac ctctgccgcc acattaacaa aaaacctcgg
    44281 gcttccagcc tgcgcgacag caaacataag aaggggtgtt tttatgtcat ccgatattaa
    44341 gatcaaagtg caaagctttg gtcgtttcct cagcaacatg gtgatgccaa atatcggcgc
    44401 gtttatcgcg tggggtatca tcaccgcgtt atttattcca acagggtggt taccgaacga
    44461 aacgctggcg aagctggtcg ggccgatgat cacttatctc ctgccgctgc tgatcggtta
    44521 taccggtggt aagctggttg gcggcgaacg tggcggcgta gtcggtgcca ttaccaccat
    44581 gggcgttatc gtcggcgcag acatgccgat gttcctcggc tctatgattg caggtccgct
    44641 gggcggctgg tgcattaagc acttcgaccg ctgggtagac ggtaagatca aatccggttt
    44701 tgagatgctg gtgaataact tctccgcagg catcatcggg atgatcctcg ctattctggc
    44761 attcctcggc attggcccga ttgttgaagc cctgtccaaa atgctggcgg cgggcgttaa
    44821 cttcatggtt gtccatgaca tgctgccgct ggcgtctatc tttgttgaac cggcgaaaat
    44881 cctgttcctc aacaacgcca ttaaccacgg tatcttctcg ccgctgggta ttcagcagtc
    44941 ccatgaactg ggtaaatcca tcttcttcct gattgaagct aacccaggtc caggtatggg
    45001 cgtgctgctg gcgtacatgt tctttggtcg tggtagcgct aaacagtctg cgggcggtgc
    45061 ggcaatcatc cacttcctgg ggggtatcca cgaaatctac ttcccgtatg tgctgatgaa
    45121 tccgcgtctg attctggccg ttatcctcgg cggtatgact ggcgtattca cgctgactat
    45181 cctgggcggt gggctggttt ctccggcatc tccgggttct atccttgctg tactggcgat
    45241 gacgccaaaa ggtgcttact tcgctaacat cgcgggtgtg tgtgcggcga tggcagtttc
    45301 cttcgttgtc tctgccattc tgctgaaaac cagcaaagtg aaagaagaag atgatattga
    45361 agctgctgca cgtcgcgttc aggaaatgaa agctgagtct aaaggtgcgt ctccgctgtc
    45421 tgcaggcgat gtgactaacg acctgagcca cgtccgtaaa atcatcgttg cctgtgatgc
    45481 cggtatgggt tccagtgcga tgggtgcagg cgtgctgcgt aagaaaattc aggatgcagg
    45541 tctgtcgcag atttcggtca ctaacagcgc gatcaacaac ctgccgccag atgtggacct
    45601 ggtcatcact caccgtgacc tgaccgaacg cgctatgcgc caggttccgc aggcacagca
    45661 tatttcgctg accaacttcc tcgacagcgg cctgtacacc agcctgaccg aacgtctggt
    45721 tgctgcccag cgccatactg aaaacgaagt gaaagtgaaa gacagtctga aagacagctt
    45781 tgacgattcc agtgctaacc tgttcaaact gggcgcggag aacatcttcc tcggtcgcaa
    45841 agcggccacc aaagaagaag cgattcgttt tgctggcgag caactggtga aaggcggtta
    45901 cgttgagccg gaatacgttc aggcgatgct ggatcgtgaa aaactgaccc cgacttatct
    45961 gggtgagtct atcgcggtgc cacacggtac ggttgaagcg aaagatcgcg tactcaaaac
    46021 gggcgtcgtg ttctgccagt acccggaagg cgtgcgcttc ggtgaagaag aagatgacat
    46081 tgcccgtctg gtgattggga ttgctgcccg taacaacgag cacattcagg tgatcaccag
    46141 cctgaccaat gcactggatg atgagtccgt catcgagcgt ctggcacaca ccaccagcgt
    46201 ggatgaagtg ctggaattgc tggcaggtcg taagtaatcc attcccaccc tctccgcatg
    46261 aagaaggtgg ggctaattgc ttgatgcgct tcgcttatca ggcctacaac ataaagcaca
    46321 atttgttttg tcggtcggat aaggtgttta cgccgcatcc ggcagtcggt gcacaatgcc
    46381 tgatgcgacg ctgacgcgtc ttatcagacc tacaggtcag tgccaaacac gtaggccgga
    46441 taaggcggtt tacgccgcat ccggcaaaaa gcccctctcc tcacggagag ggtttgggtg
    46501 agggaaaagc ctcaccccag ccctctcggg taaaaacatt gatgaaggtt aatactatga
    46561 aagcattaca ttttggcgca ggtaatatcg gtcgtggctt tatcggtaaa ctgctggcag
    46621 acgcaggtat ccaactgacg tttgccgatg taaatcaggt ggtgcttgat gccctgaatg
    46681 cccgtcatag ctatcaggtt catgtggttg gtgaaaccga gcaggtagat accgtttctg
    46741 gcgtcgatgc cgtcagcagc attggtgatg atgtcgttga tctgattgct caggttgatt
    46801 tagtcactac cgccgttggc ccggtcgtgc tggaacgtat tgctccggcc atcgccaaag
    46861 ggctggtgaa acgtaaagaa caaggtaatg aatctccgct gaacatcatc gcctgtgaaa
    46921 acatggtccg cggcaccacg cagctgaaag gccatgtgat gaacgccctg cccgaagacg
    46981 ccaaagcgtg ggtagaagaa cacgttggct ttgttgattc cgccgttgac cgcatcgtac
    47041 cgccttcggc ttcggcaact aacgatccgc tggaagtgac ggtagaaacc ttcagcgaat
    47101 ggattgtcga taaaacccag ttcaaaggca cgctgccaaa catccctggc atggaattaa
    47161 ccgacaatct gatggcattt gtcgaacgta aactcttcac cctgaataca ggtcatgcta
    47221 taaccgcgta cctcggaaaa ctggcgggtc atcagaccat tcgtgacgca attctcgacg
    47281 agaaaatccg cgcggtggta aaaggggcaa tggaagaaag tggtgcagta ttgatcaagc
    47341 gctacggctt tgacgctgac aagcatgcgg catacatcca gaaaatcctt ggtcgtttcg
    47401 agaacccgta cctgaaagat gatgtagaac gcgtaggccg tcagccgctg cgtaaactga
    47461 gtgctggcga ccgtctgatc aagccactgc tcggaaccct ggaatatggt ctgccacata
    47521 aaaacctgat tgaaggtatt gccgctgcaa tgcacttccg cagtgaagat gatccgcagg
    47581 ctcaggaact ggcagcgctg attgccgaca aaggcccaca agccgcgctg gcacagattt
    47641 ccggtcttga tgccaacagc gaggttgtat ccgaggcggt aaccgcttat aaagcaatgc
    47701 aataatggtg gaccaggcgc aggataccct gcgcccgaat aacagattgt cagatatgca
    47761 ggcaacaatg gaacaaaccc aggcctttga aaaccgtgtg cttgagcgtc tgaatgctgg
    47821 caaaaccgtg cgaagctttc tgatcaccgc cgtcgagctt ttgaccgagg cggtaaatct
    47881 tctggtgctt caggtattcc gcaaagacga ttacgcggtg aagtatgctg tagaaccgtt
    47941 actcgacggc gatggtccgc tgggcgatct ttctgtgcgt ttaaaactca tttacgggtt
    48001 gggcgtcatt aaccgccagg aatacgaaga tgcggaactg ctgatggcat tgcgtgaaga
    48061 gctaaatcac gacggcaacg agtacgcttt taccgacgac gaaatccttg gaccctttgg
    48121 tgaactgcat tgcgtggcgg cgttaccacc gccgccacag tttgaacctg cagactccag
    48181 tttgtatgca atgcaaattc agcgttacca acaggctgta cgatcaacaa tggtcctttc
    48241 actgacagag ctgatttcca aaatcagctt aaaaaaagcc tttcaaaagt aagtactttc
    48301 gcttacttct cctctacctg tttcggacga taaagctgac gataatactc cagacgttgt
    48361 agatataacg gcacgctttc atcaggtatt ccggacggaa tcgcgttacg gggaggtagt
    48421 tttttcagat actcccggaa cgcctggctc gatgccatga aatctacggc tttatcgata
    48481 agaagcggaa cgttttcacc taatttgccc atgatgatat ctccgtatta ccccgcgccg
    48541 ggaatgcgcg gccgccaatt ttagtttaga tcccggtata aatgacatta aggaaaacgt
    48601 gctcaatcct caataatcac ctgcttctgt tgactatctt ttttctttaa atttcttaac
    48661 taatcaatgt attgggtgat tttttaacgc attaatggtt acaatctgga actattacaa
    48721 tgccatcagt tgtgaacaaa gcacctggtc gcgcatacta gaggctataa atttatctct
    48781 atcagaagtc atcacatgaa agaagtcgaa aaaaacgaaa tcaaacgtct cagcgatcgt
    48841 ctggacgcca tccgtcacca gcaggccgat ctatcgctgg ttgaagccgc agacaaatat
    48901 gccgaactgg aaaaagagaa agccacgctg gaagcagaaa ttgctcgcct gcgcgaagtt
    48961 cacagccaga aactcagcaa agaagcgcag aaactgatga agatgccgtt ccagcgtgca
    49021 atcaccaaaa aagagcaggc tgatatgggc aaactgaaaa aaagtgttcg cggactggtg
    49081 gttgtgcacc caatgaccgc gctgggccgt gaaatgggcc tgcaagagat gacagggttc
    49141 tcaaagactg cgttttaagt tcctttctcg tcgctgtaac tactgccact cacgatttac
    49201 tcgctcctgc tggcacatgc aggagcctgt gccactcatt aaatacgatg tctttcttac
    49261 cgtaaactgt ttcagtttcc cctcgagttt gaggtatttt tgcaggctaa aatctgaaaa
    49321 tttgttgcgc aacaacaagt gatatataaa tcataaaaat aaataatcga attatgatgc
    49381 atgattattt atctttcccc ataaacacag caaatttcat cacaacacat catttatatg
    49441 aatataaaat ctccctgcgc tccccagcct aagacactaa acatttgaca ttgattgata
    49501 ccgctcatta aaattcgcgc gactcataac attcgctaca aactgaaatc agttgtcatt
    49561 taataaaacg tccgtaatac caattatttc aataaatctc ttataagttt tattgcgaat
    49621 acatatataa aaaacattca tcagaagaat gaatatggcg taattatcaa catattgggg
    49681 ttatgaaaag gaattcatcc tatgagcatg aaaacacttt taaacgtgtt aacaatattt
    49741 tcactaggta cattaacagg ctgtgattat attgaaaaag cgagtctgat cgatgatctt
    49801 gccaaacagc aagagttgca aaaaagtaaa atagaggagc ttgagaaaca acaagaacaa
    49861 tataaaaata aagcagaact gtttgaaaaa caacaaaata atatcacaaa cagcaccaga
    49921 atacttgcca gcattgtaaa gacagtcaaa gaaaaacagg acgaatttgt cttcaccgaa
    49981 tttaacccgc tacaaaccca atacttcatt ttaaataacg gctcggtcgg tttggcaggc
    50041 cgggtgctgg ctattgatgc ggttgaaaat ggcagtgtca ttcgtatttc gctggttaac
    50101 ttattaagcg ttcccgtatc aaatattggc tttcatgcga catgggggaa tgagaaaccc
    50161 accgatgcca aagctctggc gaaatggcaa caattactat tcaacaccac cctgaattcc
    50221 actctgcaat taatgcctgg tcaatggcaa gacattaatc tgacattaaa aggcgtctcg
    50281 cctaataacc tgaagtatct gaagttgtcc atcaatatgg ctaatcttca gttcgacact
    50341 gttcaacctg ctgaaacccg gcagcggaaa aacaaaaaat aaatgcagct tctgcgctta
    50401 tatcaaggaa tagagagcat caataatgaa caaaatattt aaagttatct ggaatccggc
    50461 gacaggcagt tacaacgtcg ccagcgaaac ggcgaagagc cgtggcaaaa agagcgggcg
    50521 cagtaagctg ttaatttctg ccttggttgc aggtgggctg ttatcgtcat ttggggcact
    50581 ggctgataac tacgaggggc agccagtgga ttatggcaat ggctcagcag gtgacggctg
    50641 ggttgctatc ggtaaaaatt caaaagcaaa tacctttgtc aatggctctg gtgcgagcac
    50701 tgcgctaggt tatgacgcga tagctgaagg tgagtacagc tcagctatag gctcacgaac
    50761 tcatgcgatt ggtggtgcat caatggcctt tggggttagt gcacaagcaa taggtgacag
    50821 aagtgtcgcg ctgggtgcat cttcagtagc aactggcggt cgttcgatgg ctcttggtcg
    50881 ttacgcaaag acgaatggtt ttacatctct tgctattggg gacaccgccc ttgccgatgg
    50941 tgaaaaaact attgcgttag gaaatacggc tcaagcttac gaaattatga gcatcgccct
    51001 cggtgatcat gctaatgcct caaaagaata ttcaatggcg ctgggagcaa gtagcgttgc
    51061 atctgcggct aacgccattg ccgtaggccg cgacagtgct gctaacggca cagacagcct
    51121 tgccttaggc agactatctc tcgccagcgc agcaaacgcg attgctatgg gtgcagagag
    51181 cgaagctgct gaaaatgcga cggcgattgg ctttaacgcg gatgcgatcg ggaagtccag
    51241 cctggcgctg ggagacaacg ccagcgctgg tgaaaccaac tccatcgcta taggtcaagg
    51301 cagcgaggca agcaaacttg attcaattgc gctgggaagt aacagcaggt cagcgggtga
    51361 gaacgccatt gcactgggca acaacagtaa tgcggggggc aaaaacagcc ttgctttcgg
    51421 ttttaacacc accgcaaatg gtgataacgc agtcgccatt ggtgcaaatt cttccgcagg
    51481 tgctgacaat accgtgtctg taggtagctc tagtttaaag cgcaaaattg tcaatatggg
    51541 taatggtgac atcaataatg tcagctccga tgccatcaat ggatcacaac tttatgccat
    51601 cagtaagtct gtatccgaca ggcttggagg atatcatgat gatcctgata atgttataaa
    51661 ctctgacggg acgcttaaag ctcccacata ttatctacaa agtggccaat acaataacgt
    51721 gggagaggct ctccagagca tcgacaataa cacgttgcac tgggacagca aaagtaataa
    51781 atacagtgcc agccatactg tctttaatgc aaatggctca gttaaaagca cctcggcgaa
    51841 aaacatcatt accgacgtcg ctgatggcac gatttcagcc accagttccg acgccgttaa
    51901 cggttcgcag ttgtataatc tgaaacaaga tgccttgcta tgggatggca ctgcgtttag
    51961 cgccaaacat ggcaccagca atactaacag caaaatcacc aacgttgcgg atggtgctgt
    52021 ttcagcctcc agtaaagatg ccgttaacgg ttcgcagttg tatgatctga aacaagatgc
    52081 cctgctatgg gatggcactg cgtttagcgc caaacatggc accagcaata ctgacagcaa
    52141 aatcaccaac gtactggcag gcacagtatc ttccaccagc accgatgcca ttaatggtac
    52201 acaacttcaa agcactgcaa gcaccattac gtcctatttg ggcggcggcg cggcaatgag
    52261 taatgacggc gtatttaccg gtcctcaata taatattggt ggtaagaatt acaccaatgt
    52321 tggcgcagct cttaccgctc tggacaatga cgccctgttg tgggatgcaa ccgctaattc
    52381 aaatactggc gcattcagtg ctgcacacgg aacactcaaa accgccagca agattaccaa
    52441 cgttgcaaat ggtgacatat tagccaacag ttatgatgct attaatggct cacaacttta
    52501 tagtttagct gattcattta cgtcatacct tggcggtggt gctgatatca acaatgcggg
    52561 tgttctcata gccccgacct atactatcgg ttcgaaaacg tacaacaacg taggtgatgc
    52621 ccttaacgcg attaactcat cattcagcac ctcaatcagt gatgccctgc tgtgggattc
    52681 tacagcgaac aaattcagcg ccaaacacgg tggtaccaat agcattatta ctaacgttgc
    52741 agacggtaca atttcctcta ccagcagcga tgctgtaaat ggctcgcaac tctatgacac
    52801 gagcaagtac attgctgatg ccctgggtgg tgacgcagaa gttaacgctg acggcaccat
    52861 gactgcaccg acttactcta tcgctaatga agattaccac agcgtaggtg aagccctgga
    52921 tgcgctcgat gataacgcgc tgctgtggga tgaagacgca ggtgcctaca acgccagcca
    52981 tgatggcaat gccagcaaaa ttaccaacgt tgcggcaggt gatctctcca caaccagtac
    53041 cgatgctgtt aacggttccc agttaaacgc aaccaatatt ctggttacgc aaaatagcca
    53101 aatgattaac cagcttgccg gtaacaccag cgaaacctac atcgaggaaa acggtgcggg
    53161 tattaactat gtacgtacca acgacaacgg cttagcgttc aacgatgcca gcgcctcagg
    53221 tattggtgct acggctgtgg gttataactc tgttgccgaa ggtgatagca gcgtggccat
    53281 tggtcaaggt agcagcagct ccgttgatac cggcattgcc ttgggtagca gctccgtttc
    53341 cagtcgcgtg attgttaaag gttctcgtaa cactagtgta acggaaaatg gcgtagttat
    53401 cggttatgac accactgacg gtgagttgct cggtgcattg tcaattggtg atgacggtaa
    53461 ataccgtcaa atcatcaacg tcgccgatgg ttccgaagcc catgacgccg ttacggttcg
    53521 ccagctgcaa aatgccattg gtgcagtcgc taccacgccg actaaatact tccacgctaa
    53581 ctcaacggct gaagactcac tggcagtcgg tgaagactcg ctggcaatgg gcgcgaaaac
    53641 catcgttaat ggtaatgcgg gtattggtat cggcctgaac acgctggttc tggctgatgc
    53701 gatcaacggt attgctatcg gttctaacgc acgcgcaaat catgccgaca gcattgcaat
    53761 gggtaatggt tctcagacta cccgtggtgc gcagaccaac tacactgcct acaacatgga
    53821 cgcgccgcag aactccgtgg gtgagttctc tgtcggcagt gaagacggtc aacgtcagat
    53881 caccaacgtc gcagcggggt cggcggatac cgatgcggtc aacgtgggtc aattgaaagt
    53941 aacggacgcg caggtttccc agaataccca gagcattact aacctgaaca ctcaggtcac
    54001 taatctggat actcgcgtga ccaatatcga aaacggcatt ggcgatatcg taaccaccgg
    54061 tagcactaag tacttcaaga ccaacaccga tggcgcagat gccaacgcgc agggtaaaga
    54121 cagtgttgcg attggttctg gttccattgc tgccgctgac aacagcgtcg cgctgggcac
    54181 gggttccgta gcagacgaag aaaatacgat ctctgtgggt tcttctacca accagcgccg
    54241 tatcaccaac gttgctgccg gtgttaatgc caccgatgcg gttaacgttt cgcaactgaa
    54301 gtcttctgaa gcaggcggcg ttcgctacga caccaaagct gatggctcta tcgactacag
    54361 caacatcact ctcggtggtg gtaacggcgg tacgactcgc atcagcaacg tctccgctgg
    54421 cgtcaacaac aacgacgcag tgaactatgc gcaactgaag caaagcgtgc aggaaacgaa
    54481 gcaatacacc gatcagcgca tggttgagat ggataacaaa ctgtccaaaa ccgaaagcaa
    54541 gttgagcggt ggtatcgctt ctgcaatggc gatgaccggt ctgccgcagg cttacacgcc
    54601 gggtgccagc atggcctcta ttggtggcgg tacttacaac ggtgaatcgg ctgttgcttt
    54661 aggtgtgtcg atggtgagcg ccaatggtcg ttgggtctac aaattacaag gtagtaccaa
    54721 tagccagggt gaatactccg ccgcactcgg tgccggtatt cagtggtaat gatccattaa
    54781 cgaatgggta aacgccacat tgcctgatgc gctacgctta tcaggcctac ggggtgattc
    54841 agcacattcc tgtaggtcgg ataaggcgtt cacgccgcat ccggcaagat aaggcactcc
    54901 gggtcaacaa tctaagggca attctctgat gaggattgcc cttttcttta ccagacatct
    54961 cccaccacaa gaattggccc taccaattct tcgcttatct gacctctggt tcacaattcc
    55021 ccaattaaaa ctcacatcaa tgttgccaac acgtaacatt tagttaacca ttcattgtca
    55081 ttacccctac acaacacaat tggcagtgcc acttttacac aacgtgtgac aaagagatgg
    55141 gcaacagact cattacacgg cgtgtgtgga ctgcaggaga cctgcaatga atctctggca
    55201 acaaaactac gatcccgccg ggaatatctg gctttccagc ctgatagcat cgcttcccat
    55261 cctgtttttc ttctttgcgc tgattaagct caaactgaaa ggatacgtcg ccgcctcatg
    55321 gacggtggca atcgcccttg ccgtggcttt gctgttctat aaaatgccgg tcgctaacgc
    55381 gctggcctcg gtggtttatg gcttcttcta cgggttgtgg cccatcgcgt ggatcattat
    55441 tgcagcggtg ttcgtctata agatctcggt gaaaaccggg cagtttgaca tcatccgctc
    55501 gtctattctt tcgataaccc ctgaccagcg cctgcaaatg ctgatcgtcg gtttctgttt
    55561 cggcgctttc cttgaaggag ccgcaggctt tggcgcaccg gtagcaatta ccgccgcatt
    55621 gctggtcggc ctgggcttta aaccgctgta cgccgccggg ctgtgcctga ttgttaacac
    55681 cgcgccagtg gcatttggtg cgatgggtat tccgattctg gtcgccgggc aggtaacagg
    55741 catcgacagc tttgagattg gtcagatggt ggggcgtcag ctgccgttta tgaccattat
    55801 cgtgctgttc tggatcatgg cgattatgga cggctggcgc ggtatcaaag aaacctggcc
    55861 tgcggtcgtg gttgcgggcg ggtcgtttgc catcgctcaa tacctcagct ctaactttat
    55921 tgggccggaa ctgccagaca ttatctcttc gctggtatcg ctgctctgtc tgacactgtt
    55981 cctcaaacgc tggcaacccg tgcgcgtatt ccgcttcggt gacttagggg cgtcacaggt
    56041 tgatatgacg ctggctcaca caggttacac ggcaggtcag gtgctgcgcg cctggacacc
    56101 gttcctgttc ctgaccgcca ccgtaacact gtggagtatc ccgccgttta aagccctgtt
    56161 cacttcaggc ggtgcgctgt atgagtgggt gatcaacatt ccggtgccgt acctcgataa
    56221 actggttgcc cgtatgccgc cagtggtcag cgaagcgaca gcgtatgccg ccgtgtttaa
    56281 gttcgactgg ttctctgcca ccggtaccgc cattctgttt gctgccctgc tctcgattgt
    56341 ctggctgaag atgaaaccat ctgacgctat cagcaccttc ggcagcacgc tgaaagaact
    56401 ggctctgcct atctactcca tcggcatggt gctggcgttc gcctttatct cgaactattc
    56461 cggtttgtca tcaacactgg cgctggcact ggcgcacacc ggtcatgcat tcaccttctt
    56521 ctcgccgttc ctcggctggc ttggggtatt cctgaccggg tcggatacgt catctaatgc
    56581 tttgtttgcc gctttgcagg ctaccgccgc acaacaaatt ggcgtttctg acctgttgct
    56641 ggttgctgcc aacaccaccg gtggtgtcac cggcaaaatg atctctccgc aatctatcgc
    56701 tatcgcctgt gcggcggtag gcctggtggg caaagagtct gatttgttcc gctttactgt
    56761 caaacacagc ctgatcttca cctgtatggt gggcgtgatc accacgcttc aggcctatgt
    56821 cttaacgtgg atgattcctt aatgattgtt ttacccagac gcctgtcaga cgaggttgcc
    56881 gatcgtgtgc gggcgctgat tgatgaaaaa aacctggaag cgggcatgaa gttgcccgct
    56941 gaacgtcaac tggcgatgca actcggcgtg tcgagaaatt cactgcgcga ggcgctggcg
    57001 aaactggtaa gcgaaggtgt gctgctcagt cgacgtggcg gcgggacgtt tattcgctgg
    57061 cgtcatgaca catggtcgga gcaaaacatc gtccagccgc tgaaaacgct gatggccgat
    57121 gatccggatt acagtttcga tattctggaa gcccgctacg ccattgaagc cagcaccgca
    57181 tggcatgcag caatgcgcgc cacacctggc gaaaaagaaa agattcagct ttgctttgaa
    57241 gcaacgctaa gtgaagaccc ggatctcgcc tcacaagcgg acgttcgttt tcatctggcg
    57301 attgccgaag cttcacataa cattgtgttg ctgcaaacca tgcgcggttt cttcgatgtc
    57361 ctgcaatcct ctgtgaagca tagccgccag cggatgtacc tggtaccccc ggttttttct
    57421 cagctgaccg aacaacatca ggcggtcatt gacgccattt ttgtcggtga tgctgacggg
    57481 gcgcgtaaag caatgatggc gcaccttagc tttgttcaca ccaccatgaa acgattcgat
    57541 gaagatcagg ctcgccatgc acgaattacc cgcctgcctg gtgaccataa tgagcattcg
    57601 agggagaaaa acgcatgatt atttccgcag ccagcgatta tcgcgccgca gcgcaacgca
    57661 ttctgccgcc gttcctgttt cactatatgg atgggggggc atattctgaa tacaccctac
    57721 gccgcaacgt ggaagatttg tcagaagtgg cgctgcgcca gcgtattctg aaaaacatgt
    57781 ctgacttaag cctggaaacg acgctgttta atgagaaatt gtcgatgccg gtggcgctag
    57841 gtccggtagg tttgtgtggc atgtatgcgc gacgcggcga agttcaggct gccaaagccg
    57901 cggatgcgca tggcattccg tttactctct cgacggtttc cgtttgcccg attgaagaag
    57961 tcgctccagc tatcaaacgt ccgatgtggt tccagcttta tgtgctgcgc gatcgcggct
    58021 ttatgcgtaa cgcactggag cgagcaaaag ccgcgggttg ttcgacgctg gttttcaccg
    58081 tggatatgcc gacaccggga gcgcgttatc gtgatgcgca ttctgggatg agcggcccga
    58141 acgcggcaat gcgccgctat ttgcaggcgg tgacgcatcc gcaatgggcg tgggatgtgg
    58201 gcctgaacgg tcgtccgcat gatttaggta atatctcggc ttacctcggc aaaccgaccg
    58261 gactggaaga ttacatcggc tggctgggga ataacttcga tccgtccatc tcatggaaag
    58321 accttgagtg gatccgcgat ttctgggatg gcccgatggt gatcaaaggg atcctcgacc
    58381 cagaagatgc gcgcgatgca gtacgttttg gtgctgatgg aattgtggtt tctaaccacg
    58441 gtggccgcca gctggacggt gtgctctctt ctgcccgtgc actgcctgct attgcagatg
    58501 ccgtgaaagg tgatatcgcc attctggcag atagcggaat acgtaacggg cttgatgtcg
    58561 tgcgtatgat tgcgctcggt gccgacaccg tactgctggg tcgtgctttc ctgtatgcgc
    58621 tggcaacagc gggccaggcg ggtgtagcta acctgctaaa tctgatcgaa aaagagatga
    58681 aagtggcaat gacgctgact ggcgcgaaat cgattagcga aattacgcaa gattcgctgg
    58741 tgcaggggct gggtaaagag ttgccggcgg cattggctcc gatggcgaaa gggaatgcag
    58801 cttaagggtt agacgaatat ctgctatcct gcccccgcac taagggggca gtatgctaaa
    58861 catcgtactt tacgaaccag aaattccgcc aaatactggc aacatcatcc gtctttgcgc
    58921 taataccggc tttcgtctgc atatcatcga accgatggga tttgcctggg acgataagcg
    58981 cctgcgccgc gcggggctgg actatcacga gtttaccgcc gttacgcgtc atcatgacta
    59041 tcgcgcgttt ctcgaagcag aaaatcccca gcgtctgttt gccctcacca cgaaaggtac
    59101 gcctgctcac agcgccgtaa gctatcagga tggcgattat ctgatgttcg gcccggaaac
    59161 acgcggcctg ccagcgagca ttcttgatgc cctgcccgct gaacaaaaaa ttcgtattcc
    59221 aatggtgccg gacagccgca gcatgaacct gtccaatgcg gtgtcggtcg tggtgtatga
    59281 agcctggcgg cagttggggt atccgggagc ggtattgaga gattagttac tgtaggccgg
    59341 atagatgatt acatcgcatc cggcacgatc acaggacatc agatcccatc accatactca
    59401 aacgtatggt taatgccgtt gaaatgctga tccatatcca ttgacggttt atcgctatcc
    59461 ggcttgccga caatgcgtgc cggaacgcca gcggcagtag tgtgcggcgg caccggttgc
    59521 agcaccacgg aacctgcgcc aatcttcgcg ccgcgcccaa cttcaatatt gccgagaatt
    59581 ttcgcgcccg cgccaatcat cacaccttca cgaattttcg ggtgacggtc gccaccagat
    59641 ttacccgtac cgccaagcgt cacagattgc agaatcgata cgtcgttttc aatcaccgcc
    59701 gtttcaccaa cgacgatgcc tgtcgcgtgg tcgagcatga taccgcgacc aatttttgct
    59761 gccgggtgaa tatcaacctg gaacgtcaca gaaacctggt tttgcagaaa aatagccagt
    59821 gcgcgacgcc cctgattcca caaccagtga ccgatgcgat acgcctgcaa agcatgaaaa
    59881 cccttcaggt atagcaacgg ggttgagtat ttatccaccg ccgggtcacg ggtacgcacc
    59941 gcctgaatat cacaggccgc agaggcgatc atttccgggt cggcggcgta ggcttcttcc
    60001 accacttcac ggatagcaat agccggcata atgggcgatg acagcttgtt cgccagcatg
    60061 tagctcagtg cactgccaag gttttcgtgc ttgagtagcg tcgcgtggta aaaactggcc
    60121 agcattggct cacagtccgc cagcgttctg gcttcagctt taatattgtt ccagacaatt
    60181 tccagttctt cacacgacat tgcttactcc acacgatgag ataatgaccg acccgttctg
    60241 cgcgggccgg gtcatagtgg taacaaaggt tccctgggtt tagtggctgc tgcgctcgtc
    60301 cttgcgtgca cgacctagta aagtcaatgc tgcctcgcgc gcgttttttc cgcaatataa
    60361 tacttgataa atttcctcgg ttattggcat ttcaacgccg aagcgatgcg ccagttcgcg
    60421 gacttctttc gtattgcggt agccttccac cacttgacca attttctcct gcgcgctttg
    60481 tacatccatg ccctgaccga gcatcatgcc aaaacggcgg ttacgcgact ggttgtcggt
    60541 acaggtaagc accagatcgc ccagccccgc catgcccata aaggtggcag gatcggcacc
    60601 cagcgccgcg ccaagacgcg acatctcagc cagcccacga gtgatcagcg ccgtacgcgc
    60661 attcgcacca aaaccgatac cgtcggacat ccccgcgcca atggcaatga cgtttttcac
    60721 cgcgccgcca agctgcacac cgatgaaatc cgggttgctg taaacgcgga aacttttgcc
    60781 acagtgcagc aattgctgga ggtcatcggc aaaggtctgg tccgtcgagg ccagcgaaat
    60841 ggccgtcggt aaacctgccg ccagttcttt cgcaaacgtt gggccagaga taaccgccag
    60901 cggaatttga tcgcctaagg cctcacgcgc cacgtcctgt aacagacgtc cggtttctgc
    60961 ttccagccct ttggttgccc acaccagacg cgcatcagga cgcatcagcg gtttaatctg
    61021 gcgcagcact tcaccaaaga catggctggg tacgacgacg agaatattac ggctggctgc
    61081 cagcgcagtg gcgagatcgc tttcaagatg gagcgtatcg ggaaaaggca catcggggag
    61141 aaacgcggcg ttacagcggt cgcgttcaag cgttgcgata tgttcagggt catggcccca
    61201 gaggacaacc tcgtggccat ttcttgccag ggtgatggca agagcggtgc cgtacgagcc
    61261 ggcaccgatc acagtcattg aagcattacg ttggttcatc aggcatcctg atgttcttca
    61321 gtaccttcgc cagcctgctg ctgcaaatag ttcatgaaca gcgcatcgaa gttaaccggc
    61381 gcaaggttca gttgcgggaa tgtaccgcgg gataccatgc tggtgatgca ctcacgagca
    61441 tacgggaaca gaatgttcgg gcagtatgcg cccaggcaat gtgccatctg ggtgccttcg
    61501 atacccgcga tggagaaaat accgccctgc tgaacttcac acaggaacgc ggtttcttcg
    61561 cccagggagg ccgttacggt aacacgcagt accacttcgt aaacgtcatc tgccagttga
    61621 gtagatgccg tatccagatc aagtttaact tctggttgcc aatctttctg gaaaacgtgc
    61681 ggcgcgttcg gcgcttcgaa agaaatatcc ttggtataaa tacgttggat ctggaaagtc
    61741 atttcggtgt tgttttgttc tgacatgtgt agaaaaccct taagtgttgt ccttaaaata
    61801 ctgcgcaatg taatgccaac gttcacacgt tatttcagca ggggatccag tccaccacgt
    61861 gcatccaatg catacaagtc atcacagcca ccaatgtgct gtgcgtcaat aaaaatctgt
    61921 ggaaccgtgg tgcgaccgct gcgtttgatc atctcttcac gcttagcggc attgccatcg
    61981 atcggcaact cctgaaaact cacgcccttg ctgcttagca gtgcttttgc acgatggcaa
    62041 tacgggcagg tttctttggt atagatttca acattggcca taaattagct cctgtttttt
    62101 accctgaaat ttcatgttgc agggcggcag caaaatggag tgtccccaga agcttatatc
    62161 aataagtcgc tgggggccta attgcagcta acggcctgca tcatgaaaga cgacaggtaa
    62221 attatttgcc gcgcaccaaa ggcaagtttt cgccagccca gccagcgacg ccttctttca
    62281 gtacgaatac ttgtgcaaaa ccagctttcg tcagcgcgtt tgcaggctcc tggcactgca
    62341 tgccagaacc atctaccacg ataaccggtt tgtctttgtg cttctcaagc tcaccaacat
    62401 tgttggcttt gatttcgctc ggcaacaggt tgatagaacc tgcgatatgg cctttacgga
    62461 agtcatcacg ctgacgtaaa tccacaacca cagcgtcttc tttgttgatc agacgcgtag
    62521 cttcaccacg agtaatcacc ttcactttcg aggtcaggct cttaaacgta gtcacaagaa
    62581 ccgccaccag taacgcgatc caggcgatac tcagtatggg atgacggcca acaaattgca
    62641 taatttcttg catggggggt aacaactccc gacgtagtga ttaaaaaacc aggaaaggag
    62701 tatacctgcg cagtgcggca aatacagcca gcgcgttaac tggaatgcaa ttttgcgggg
    62761 cgctacgaaa aaaaagcgta aatctggcat ctgcttgccg cgagcggtcg tatattttga
    62821 tcttcagagg ctattttatc gattcagctg tagtaaaatt acgcaaattt tgactcttga
    62881 gtatgaggtt gtcgcaatgt cggtttctaa aaaacctatg gtactggtga ttctggatgg
    62941 ctatggctat cgcgaagaac agcaggataa cgccattttt agtgctaaaa ccccggtaat
    63001 ggatgcactg tgggccaatc gtccgcatac cctgatcgac gcttccggtc tggaagtcgg
    63061 tctgcctgac cgtcagatgg gtaactccga agtaggccac gttaacctgg gtgcaggccg
    63121 catcgtgtat caggacctga ctcgtctgga cgttgaaatc aaagatcgca ctttctttgc
    63181 taatccggtg ttgactggtg cggtagataa agcgaaaaac gcaggcaaag cagtacacat
    63241 tatgggtctg ctctccgcag gtggtgtaca cagccacgaa gatcacatca tggcgatggt
    63301 agaactggca gctgaacgcg gcgcagaaaa aatctaccta cacgcattcc ttgacggtcg
    63361 cgacactccg ccgcgcagtg ctgaatcctc gctgaaaaaa ttcgaagaga aatttgccgc
    63421 gctgggtaaa ggccgcgtag cgtccatcat tggtcgttac tacgcgatgg accgcgataa
    63481 ccgttgggat cgcgttgaaa aagcttatga cctgctgact ctggcgcaag gtgagttcca
    63541 ggccgatacc gccgttgccg gtttgcaggc tgcttatgct cgcgacgaaa acgacgagtt
    63601 cgtgaaagcg accgttattc gtgcagaagg tcagccagat gcggcaatgg aagacggcga
    63661 tgcgctgatt ttcatgaact tccgtgctga ccgcgcacgt gaaatcactc gtgcattcgt
    63721 aaatgccgat tttgacggct tcgcgcgtaa gaaagtggtt aacgtcgatt tcgtgatgct
    63781 gaccgaatac gctgccgaca tcaaaaccgc agtggcttac ccacccgctt ccctggttaa
    63841 caccttcggc gagtggatgg cgaaaaacga caaaactcag ctgcgtattt ccgaaaccga
    63901 aaaatatgcc cacgttactt tcttcttcaa cggtggcgta gaagagtcgt tcaaaggcga
    63961 agatcgcatt ctgatcaact caccgaaagt ggctacctac gatctgcaac cggaaatgag
    64021 ctccgcagag ctgaccgaaa aactggttgc ggcaatcaag agcggcaaat acgacaccat
    64081 tatctgtaac tatccgaacg gcgacatggt aggtcacacc ggggtgatgg aagcggcggt
    64141 taaagcggtt gaagcgctgg atcactgcgt ggaagaagtc gcgaaagcgg ttgagtccgt
    64201 gggtggacaa ctgctgatca ccgctgacca cggtaacgct gaacagatgc gcgatccggc
    64261 aacgggtcag gcacacacag cacacaccaa cctgccagtt ccgctgattt acgttggtga
    64321 taagaacgtg aaagcggttg aaggcggcaa actttctgac atcgcgccga ccatgttgtc
    64381 gctgatgggt atggaaatcc cgcaagagat gactggtaag ccgctgttca tcgtggaata
    64441 atccctcccc atgaggggaa aggcgattaa taccatgaca cgggccgtga aaccgcgcag
    64501 gtttgcaatc aggcccatca tctacgccag cgttctgagc gctggcgtat tgttgtgcgc
    64561 cttttccgcc cacgcggatg agcgtgacca actcaaatcc attcaggctg acatcgccgc
    64621 gaaagagcgc gcggtacgcc aaaagcaaca acaacgcgca agcctgctcg cacaattgaa
    64681 aaagcaggaa gaagcgatct ctgaagccac ccgtaaactg cgcgaaacgc aaaacacgct
    64741 taatcaactg aataaacaga ttgatgagat gaacgcgtcg attgccaaac tggagcagca
    64801 aaaagccgcc caggagcgca gcctcgccgc gcaactggat gccgcgtttc gtcagggtga
    64861 acataccggt attcagctga ttctcagcgg tgaagaaagc cagcgtgggc agcggttaca
    64921 ggcttatttc ggctatctca accaggcgcg acaagaaacc attgctcagt tgaaacaaac
    64981 gcgtgaagaa gtcgctatgc agcgtgccga actggaagag aaacaaagcg agcaacaaac
    65041 gcttttatat gagcagcgcg cccaacaggc gaagctgacc caggcgttga gcgagcgtaa
    65101 aaagacgctg gcagggctgg agtcttccat ccagcaaggt cagcaacagt tgagcgagct
    65161 gcgcgccaac gaatcccgcc tgcgtaacag cattgcccgt gcggaagccg cggcgaaagc
    65221 gcgtgctgaa cgtgaagcgc gcgaagccca ggcggttcgc gaccgccaga aagaagcgac
    65281 gcgcaaaggc accacctaca agccgaccga aagcgaaaaa tcgctgatgt cccgtaccgg
    65341 tggtctgggc gcaccgcgcg gtcaggcatt ctggccggtt cgcgggccaa cgctgcatcg
    65401 ctatggcgag cagctacagg gtgaattacg ctggaaaggg atggtgattg gtgcctctga
    65461 aggtactgaa gttaaagcga ttgccgacgg ccgggtgatt ctggctgact ggctgcaagg
    65521 ctacggtctg gtggtggtgg ttgagcatgg taaaggcgac atgagtcttt acggctataa
    65581 tcagagcgca ctggtgagcg ttggttcgca ggttcgcgcg ggccagccaa ttgcactggt
    65641 gggcagcagt ggcggtcagg gtcggccttc actctatttc gaaattcgcc gccagggtca
    65701 ggcggtcaat ccacagccgt ggttgggaag ataagttttg tttccatttc gtcgtaacgt
    65761 tcttgcattt gccgctctgt tggcgctctc ctcccccgta attgctggca aacttgccat
    65821 cgtcattgat gattttgggt atcgcccgca caacgaaaac caggtgctgg cgatgccttc
    65881 cgctatctcc gtcgctgtat tacccgattc accgcacgcc agagagatgg cgaccaaagc
    65941 acataacagc ggtcacgaag tgttgattca tctaccgatg gcaccactga gtaaacagcc
    66001 gctggagaaa aatacgctac gcccggagat gagcagcgac gaaattgagc gcattattcg
    66061 tagtgcggtc aataacgtgc cctatgccgt ggggatcaac aaccacatgg gcagcaagat
    66121 gacctctaac ctgtttggta tgcagaaagt gatgcaggcg ctggagcgtt acaatcttta
    66181 ctttctcgac agcgtaacca tcggtaatac ccaggcgatg cgcgccgcgc aaggcactgg
    66241 cgtgaaggtg atcaaacgga aggtgttcct cgacgattcg cagaacgaag cggacatccg
    66301 tgtgcaattc aatcgcgcaa ttgacctagc gcgtcgcaac ggttcaacca ttgccattgg
    66361 gcatcctcac ccttcaacgg tacgcgtgct acaacagctg gtttataacc tgccgccaga
    66421 cattacgctg gtgaaagcca gcagcttgct gaatgaaccg caggttgata cgtctacacc
    66481 gccgaaaaac actgtgcccg acacaccgcg taatccgttc cgtggcgtga agctgtgcaa
    66541 accgaagaag ccgctggaac ctgtttatgc taatcgcttc tttgaagtat taagcgaaag
    66601 catcagccag agcacgctga tcgtttactt ccagcatcag tggcaaggct ggggcaaaca
    66661 gcccgaagcg gcaaaactta acgctagcgc aaattaaagg cgctacgcgt aatgcgatgg
    66721 tgcgaccgcg ttttgtcgcg ccattgccat aagcggaaag accacagtaa cgcctggtaa
    66781 cccaccttca cgctgcggac attggtaatc aggcgcttat acataccgga agtaaatatc
    66841 tcggcaatca tccgttggcg ggtaagaata tccggctctt tgcgcaccgc atggcaaaca
    66901 cgcaatgctt cgtaagttat ttgctgatga aattccggat aaatcgtaat tttgtcagca
    66961 taatttcgat ttaatttctc cagcaggcgg gtaatcttaa tatagtgacg ttgataatta
    67021 aggtttttat tcccttgtct atgcaaccga ctcactgacg tattatgcag ataatattta
    67081 tataatgatt gctcggtata tcgcgcacgc agcgcgttaa acataaattc tgttgtccag
    67141 acaatatcct gatgatgtaa tccggcaata aatttaatgt tatttttaac aataacatcg
    67201 cggcgataaa cccccatcca gaccacgtgt gtccaacggc gggaagaaag tcccatccgc
    67261 agccagtccg gaccggttaa tacaccggtt gagcgaaggc gatcggtggg gatggattgc
    67321 caggtttcac ccgtttcacg aaaacaccaa tcagcgttgc actgcgccac gtcgaggtca
    67381 tcctctaacg ccatggtcat cagcgtttcg tacatggtgg gatagacctc atcgtcagca
    67441 tcgacaaaag cgacatattt tcccgttgcc acttcaatcc cacgattacg cgccaccgat
    67501 gcgccagcat tcgcctgatg caacaaacga acgtgcggat agttttctgc gtaatgcttt
    67561 gctatttcaa cagaattatc cgttgaacca tcgttaataa taatgatttc cagagcagtc
    67621 catgtttgcg taattaaaga ttccatacaa gtgcggaaat catcgcccgc attatataac
    67681 gggataataa cactaagttt attggtgctg ttcatcataa attaccgacg acctctgaag
    67741 ttatcctgac gttttacagg ctttgtatta agaaactatt aagcctgtga gatattattt
    67801 ttaccggtga gagagtcact tcagggtaga gagataatga gagcagctat ataagagatc
    67861 agtgcaatta cgaactcttt attacactga caggatttta catatttaac ggattatcct
    67921 caggcaaaag ggctggaata ccagcccttg ttcgtgttaa tcccagctca gaataacttt
    67981 cccggactgg cccgaacgca tagcgtcaaa gcccttctgg aaatcatcga tagagaaacg
    68041 atgggtaatg atcggcgaga gatcgaggcc agactgaatc agcgccgcca tcttgtacca
    68101 ggtttcaaac atctcacgac cgtaaatacc tttaatgaac aagcctttaa agattacttt
    68161 ggtccagtcg atagacatat cggacggtgg aatacccagc atcgcaatac gaccgccgtg
    68221 gttcatggtg tcgagcatgg tacgaaacgc tggcggcgca ccggacattt ccagaccgac
    68281 atcaaagcct tcggtcatgc ccagttctgc catcacatca ttaaggtttt ctttagcgac
    68341 gttaaccgca cgggtgatac ccattttgcg tgccagctca aggcggtatt cgttaacatc
    68401 agtgatcacc acattgcgtg caccaacgtg tttcgccacc gccgcagcca taatacctat
    68461 cggacctgca ccagagacca gcacatcctc gccaaccaga tcgaacgaca gcgcggtatg
    68521 cacggcgtta ccgaagggat caaaaatgga agccaggtcg tcggagatat tgtctgggat
    68581 tttgaaggcg ttgaacgccg gaatcaccag atactcggcg aagcagcccg gacggttaac
    68641 accgacgccg atcgtgttgc ggcacagatg ggtacgaccg ccacgacagt tgcgacagtg
    68701 accgcaggtg atatggcctt cgccagaaac gcgatcgcca atcttgaagc ctttcacttc
    68761 ctgaccaata cctaccactt caccgacata ttcatggccc acgaccatcg gcaccgggat
    68821 ggttttttgc gaccactcat cccagttata gatgtgaacg tcagtcccgc agatggctgt
    68881 tttacggatt ttaatcagca gatcgttatg cccgagttcc ggtacaggaa cgtcggtcat
    68941 ccagatgccc tcttccgctt tcagtttgga taacgctttc atctcacacc ctcaggcgat
    69001 aacgcccagt tgtttaccaa tacgcgtgaa tgcttctact gcacgcgtaa tttgctcagg
    69061 ggtatgcgcc gcagacatct gggtacgaat acgcgcctga cctttaggaa cgaccggata
    69121 gaagaaaccg gtgacgtaaa tgccctcttt ttgcagttca cgggcaaatt tttgcgccac
    69181 tacagcatcg ccaagcatga ccggaataat ggcgtgatcg gcacccgcca gggtaaagcc
    69241 cgccgccgac atctgctcac ggaactgacg cgcgttcgcc cacagacggt cacgaagctc
    69301 actgcccgct tcgaccatct ccagcacttt aatggaagca gccacaatgg caggtgccag
    69361 tgagttggag aacaggtaag gacgagaacg ctgacgcagc cactcaacca cttctttacg
    69421 cgctgcggtg taaccaccag aagccccgcc caacgcttta ccaagcgtac cggtgataat
    69481 atcgacccgc cccatcacat cgcagtattc atgggaacca cgaccatttt caccgacaaa
    69541 accgaccgcg tgggagtcgt ctaccatcac cagggcatcg tatttatctg ccagatcgca
    69601 aacgcccttc aggttggcaa tcacgccgtc catcgagaac acaccatcgg tggcaatcag
    69661 cacatgacgc gcaccggctt cacgcgcttc tttcagacga gcttccagct catgcatatc
    69721 gttgttggca taacgatagc gtttagcttt acacagacgc acaccatcaa taatagacgc
    69781 gtggttcagt gcgtcggaga taatggcgtc ctccgcgctc agaagcgttt caaacaggcc
    69841 gccgttagca tcaaagcagg aagagtagag aatcgcatct tccatcccca ggaatgccgc
    69901 cagtttttgt tcaagctctt tatggctatc ctgggtgccg cagataaagc gcaccgaagc
    69961 catcccaaaa ccatgagagt ccattcccgc ttttgccgcc gcaatcagct ctggatgatt
    70021 tgccagtccg agatagttat tggcgcaaaa gttaataacg tggcttccat cagccacagt
    70081 gatatctgct tgctgcgcag acgtaataat gcgctcttct ttaaacaacc cttccgcccg
    70141 tgcggtttcc agatcgttgg ttaactgctg ataaaattct ccacgcattg cgattctcca
    70201 gacagggcaa attccagcac atattaccca aacttctagg tcgcgacgag atgacgcgtt
    70261 aacacttctg caaaattcag gataaataac gtccatcaat ctcacttttg gcgaatggct
    70321 gaagccaacg ccgtgtagtg atatgataga agtattcgtg tctgagattg tctctgactc
    70381 cataattcga aggttacagt tatgatcatc gttaccggcg gcgcgggctt tatcggcagc
    70441 aacatcgtta aggccctgaa tgataaaggc atcaccgata ttctggtggt ggacaacctg
    70501 aaagacggca ccaagtttgt gaacctggtg gatctggata tcgcggacta tatggataag
    70561 gaagacttcc tgatccagat tatggctggc gaagagttcg gcgatgtcga agcgattttc
    70621 cacgaaggcg cgtgctcttc caccaccgag tgggacggca agtatatgat ggataacaac
    70681 tatcaatact ccaaagagct gctgcactac tgtctggagc gcgaaatccc gttcctgtat
    70741 gcctcttccg cagccactta cggtggacgc acctccgact ttattgaatc ccgcgaatat
    70801 gaaaaaccgt tgaatgtcta cggttactca aaattcctgt ttgatgaata tgttcgccaa
    70861 atcctgcctg aagcgaactc gcagattgtt ggcttccgtt atttcaacgt ttatggacct
    70921 cgtgaaggcc ataaaggcag tatggcgagc gtcgctttcc atctcaacac ccagcttaat
    70981 aacggtgaat caccgaagct gttcgaaggt agcgagaact ttaaacgtga cttcgtctat
    71041 gtgggcgacg tggcagatgt aaacctgtgg ttcctggaaa atggcgtttc cggcatcttc
    71101 aacctcggca ccggtcgtgc ggaatccttc caggcagtag cagatgctac gcttgcttat
    71161 cacaagaaag gccaaatcga atacattccg ttcccggata aactgaaagg ccgctaccag
    71221 gcgttcactc aggcagatct gacgaatctg cgcgcggcgg gttacgataa accgttcaaa
    71281 accgttgccg aaggcgtaac ggaatacatg gcctggctga atcgtgacgc ataagagctc
    71341 tgcatgaaaa tactggtgat cggcccgtct tgggttggcg acatgatgat gtcgcaaagt
    71401 ctctatcgca cgctccaggc gcgctatccc caggcgataa tcgacgtgat ggcaccggca
    71461 tggtgccgtc cattattatc gcggatgccg gaagttaacg aagctatccc tatgcctctc
    71521 ggtcacggag cgctggaaat cggcgaacgc cgcaaactgg gtcatagcct gcgtgaaaag
    71581 cgctacgacc gcgcctacgt cttacctaac tccttcaaat ccgcattagt gcctttcttc
    71641 gcaggtattc ctcatcgcac cggctggcgc ggcgagatgc gctacggttt actcaacgat
    71701 gtacgcgtgc tcgataaaga agcctggccg ctaatggtgg aacgctatgt cgcgctggcc
    71761 tatgacaaag gcattatgcg tacagcacaa gatctgccgc agccattgtt atggccgcag
    71821 ttgcaggtga gcgaaggtga aaaatcatat acctgtaatc aattttcgct ctcatcagaa
    71881 cgtccgatga ttggtttttg cccgggtgcg gagtttggtc cggcaaaacg ctggccacac
    71941 taccactatg cggagctggc aaagcagctg attgatgaag gttatcaggt ggttctgttt
    72001 ggctcggcga aagatcatga agcgggcaat gagattcttg ccgctttgaa taccgagcag
    72061 caggcatggt gtcggaacct ggcgggggaa acacagcttg atcaagcggt tatcctgatt
    72121 gcagcctgta aagccattgt tactaacgat tctggcctga tgcacgttgc ggcggcgctc
    72181 aatcgtccgc tggttgccct gtatggtccg agtagcccgg acttcacacc accgctatcc
    72241 cataaagcac gcgtgatccg cctgattacc ggctatcaca aagtgcgtaa aggtgacgcg
    72301 gcggagggtt atcaccagag cttgatcgac attactcccc agcgcgtact ggaagaactc
    72361 aacgcgctat tgttacaaga ggaagcctga cggatgcggg ttctgatcgt taaaacatcg
    72421 tcgatgggcg atgttctcca tacgctgccc gcactcactg atgcccagca ggcaatccca
    72481 gggattaagt ttgactgggt ggtggaagaa gggttcgcac agattccttc ctggcacgct
    72541 gccgttgagc gagttattcc tgtggcaata cgtcgctggc gtaaagcctg gttctcggcc
    72601 cccataaaag ctgaacgcaa agcgtttcgt gaagcgctac aagcagagaa ctatgacgca
    72661 gttatcgacg ctcaggggct ggtaaaaagc gcgacgctgg tgacgcgtct ggcgcatggc
    72721 gtaaagcatg gaatggactg gcaaaccgct cgcgaaccgt tagccagcct gttttacaat
    72781 cgtaaacatc atattgcaaa acagcagcac gccgtagaac gcacccgcga actgtttgcc
    72841 aaaagtctgg gctatagcaa accacaaacc cagggcgatt atgctatcgc acagcatttc
    72901 ctgacgaacc tgcctacaga tgctggcgaa tatgccgtat ttcttcatgc aacaacccga
    72961 gatgataaac actggccgga agaacactgg cgagaattga ttggtttact ggctgattca
    73021 ggaatacgga ttaaacttcc gtggggcgcg ccgcatgagg aagaacgggc gaaacgactg
    73081 gcggaaggat ttgcttatgt tgaagtattg ccgaagatga gtctggaagg cgttgcccgc
    73141 gtactggccg gggctaaatt tgtagtgtcg gtggatacgg ggttaagcca tttaacggcg
    73201 gcactggata gacccaatat cacggtttat ggacctaccg atccgggatt aattggtggg
    73261 tatgggaaga atcagatggt ttgtagggct ccaagagaaa atttaattaa cctcaacagt
    73321 caagcagttt tggaaaagtt atcatcatta taaaggtaaa acatgctaac atcctttaaa
    73381 cttcattcat tgaaacctta ctctcttaaa tcatcaatga ttttagagat a
//
LOCUS       DAPOXO010000010        73316 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPOXO010000010 DAPOXO010000000
VERSION     DAPOXO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 73316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73316
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.010"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            118..1047
                     /gene="pfkB"
                     /locus_tag="ROH59_000889"
     CDS             118..1047
                     /gene="pfkB"
                     /locus_tag="ROH59_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416237.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HDX4803409.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGTATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQG
                     IRCIVDSSGEALSAALAIGNIELVKPNHKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
     gene            1148..1438
                     /gene="ghoS"
                     /locus_tag="ROH59_000890"
     CDS             1148..1438
                     /gene="ghoS"
                     /locus_tag="ROH59_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDX4803410.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDDG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTHSATGKDPEITITTWEEWNSNRK"
     gene            1544..2404
                     /locus_tag="ROH59_000891"
     CDS             1544..2404
                     /locus_tag="ROH59_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDX4803411.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGRDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(2445..2981)
                     /locus_tag="ROH59_000892"
     CDS             complement(2445..2981)
                     /locus_tag="ROH59_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HDX4803412.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENQE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            3128..3796
                     /gene="hxpB"
                     /locus_tag="ROH59_000893"
     CDS             3128..3796
                     /gene="hxpB"
                     /locus_tag="ROH59_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HDX4803413.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVEQVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLANVKLSSLTELTAK
                     DLLG"
     gene            3960..4550
                     /locus_tag="ROH59_000894"
     CDS             3960..4550
                     /locus_tag="ROH59_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310461.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX4803414.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPESWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            4683..6074
                     /gene="tcyP"
                     /locus_tag="ROH59_000895"
     CDS             4683..6074
                     /gene="tcyP"
                     /locus_tag="ROH59_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HDX4803415.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLTA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGLLLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHR"
     gene            complement(6121..6384)
                     /gene="cedA"
                     /locus_tag="ROH59_000896"
     CDS             complement(6121..6384)
                     /gene="cedA"
                     /locus_tag="ROH59_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HDX4803416.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQENEVEE"
     gene            6567..8828
                     /gene="katE"
                     /locus_tag="ROH59_000897"
     CDS             6567..8828
                     /gene="katE"
                     /locus_tag="ROH59_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HDX4803417.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDTNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAVPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQVAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     RLFWLSQTPFEHRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPNVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIANNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIAEADRADGSFMDELLTLMTAHR
                     VWSRIPKIDKIPA"
     gene            complement(8875..9633)
                     /gene="chbG"
                     /locus_tag="ROH59_000898"
     CDS             complement(8875..9633)
                     /gene="chbG"
                     /locus_tag="ROH59_000898"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDX4803418.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVAKFAAEEGIALRIDRQSLSKDG
                     DLPANLRSSQGFSSAFYGEEISETLFLQVLDDSSHRGERSLEVMCHPAFIDNTIRQSA
                     YCFPRLTELDVLTSASLKYAIAERGYRLGSYHDV"
     gene            complement(9646..10998)
                     /gene="celF"
                     /locus_tag="ROH59_000899"
                     /gene_synonym="chbF"
     CDS             complement(9646..10998)
                     /gene="celF"
                     /locus_tag="ROH59_000899"
                     /gene_synonym="chbF"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDX4803419.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGG
                     KAKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASGVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGHIDNIPADWAVEMTCTLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(11101..11943)
                     /gene="chbR"
                     /locus_tag="ROH59_000900"
     CDS             complement(11101..11943)
                     /gene="chbR"
                     /locus_tag="ROH59_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HDX4803420.1"
                     /translation="MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDY
                     YEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
                     YREEQVIDDIPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLT
                     EFNQ"
     gene            complement(11951..12301)
                     /gene="chbA"
                     /locus_tag="ROH59_000901"
     CDS             complement(11951..12301)
                     /gene="chbA"
                     /locus_tag="ROH59_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HDX4803421.1"
                     /translation="MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKMKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(12352..13710)
                     /gene="chbC"
                     /locus_tag="ROH59_000902"
     CDS             complement(12352..13710)
                     /gene="chbC"
                     /locus_tag="ROH59_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HDX4803422.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVHRNWVIKLPDSVPTSVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQ
                     YGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANAL
                     KF"
     gene            complement(13795..14115)
                     /gene="chbB"
                     /locus_tag="ROH59_000903"
     CDS             complement(13795..14115)
                     /gene="chbB"
                     /locus_tag="ROH59_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HDX4803423.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(14414..14752)
                     /gene="osmE"
                     /locus_tag="ROH59_000904"
     CDS             complement(14414..14752)
                     /gene="osmE"
                     /locus_tag="ROH59_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HDX4803424.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQATK"
     gene            14954..15781
                     /gene="nadE"
                     /locus_tag="ROH59_000905"
     CDS             14954..15781
                     /gene="nadE"
                     /locus_tag="ROH59_000905"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDX4803425.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSIDFLKSYLQTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAIRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            16011..16898
                     /gene="cho"
                     /locus_tag="ROH59_000906"
     CDS             16011..16898
                     /gene="cho"
                     /locus_tag="ROH59_000906"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HDX4803426.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRASNLFGLFANRRAALQALQTIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQALERLRVVCW
                     PWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLKEATTLIRAPAGFDHDGYKILCKPL
                     LSGNYEITELDPVNDQQAS"
     gene            complement(16858..17433)
                     /gene="ves"
                     /locus_tag="ROH59_000907"
     CDS             complement(16858..17433)
                     /gene="ves"
                     /locus_tag="ROH59_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310475.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HDX4803427.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASITSIA
                     ANGEFSLFPGMERIVTLLEGGEMFLESADRFNHTLKPLQPFSFAADLVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(17636..18121)
                     /gene="spy"
                     /locus_tag="ROH59_000908"
     CDS             complement(17636..18121)
                     /gene="spy"
                     /locus_tag="ROH59_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HDX4803428.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKF
                     GPHEDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAE
                     AQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(18451..19419)
                     /gene="astE"
                     /locus_tag="ROH59_000909"
     CDS             complement(18451..19419)
                     /gene="astE"
                     /locus_tag="ROH59_000909"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HDX4803429.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPRFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMANDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(19412..20755)
                     /gene="astB"
                     /locus_tag="ROH59_000910"
     CDS             complement(19412..20755)
                     /gene="astB"
                     /locus_tag="ROH59_000910"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HDX4803430.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQ
                     GLLKMKKLADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEKKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLAN
                     LRARVSGFMAIEVPTAQVSVSDAVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWCY
                     LNELLAADNPISSLKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLREGREALDTLTQLLDLGSVYPFQREGGGNG"
     gene            complement(20752..22230)
                     /gene="astD"
                     /locus_tag="ROH59_000911"
     CDS             complement(20752..22230)
                     /gene="astD"
                     /locus_tag="ROH59_000911"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HDX4803431.1"
                     /translation="MTLWINGDWVTGQGALRVKRNPVSGEVLWQGNDADAAQVEQACR
                     AARAAFPRWARLSFSDRQVRVERFAGLLESNKAELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLLPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGTQGDAFLARLVAVSQRLTPGTWDDEPQPFIGGLISEQAAQQVVTAW
                     QELEAMGGRPLLAPRLLQAGTSLLTPGIIEMTGVTGVPDEEVFGPLLRVWRYDNFDEA
                     IRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(22227..23261)
                     /gene="astA"
                     /locus_tag="ROH59_000912"
     CDS             complement(22227..23261)
                     /gene="astA"
                     /locus_tag="ROH59_000912"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HDX4803432.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSVRIERAI
                     KTWQGELPKSEQGYVFVLEDSESGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(23258..24478)
                     /gene="astC"
                     /locus_tag="ROH59_000913"
     CDS             complement(23258..24478)
                     /gene="astC"
                     /locus_tag="ROH59_000913"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HDX4803433.1"
                     /translation="MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWEQQGKEYIDF
                     AGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
                     NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
                     LPPDIRHAAYNDINSASALIDDATCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECASVMTVG
                     THGTTYGGNPLASAVAGKVLDLINTPEMLNGVKQRHDWFVERLNSINHHYSLFSEVRG
                     LGLLIGCVLNADYAGQAKQLSQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLER
                     FAAACEHFVSRGSS"
     gene            24924..25730
                     /gene="xthA"
                     /locus_tag="ROH59_000914"
     CDS             24924..25730
                     /gene="xthA"
                     /locus_tag="ROH59_000914"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDX4803434.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPISVRRGFPGDDEEAQRRIIMAEIPSPLGN
                     ITVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRENPVLIMGDMNISPGDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMERLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
     gene            25897..26607
                     /locus_tag="ROH59_000915"
     CDS             25897..26607
                     /locus_tag="ROH59_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416264.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDX4803435.1"
                     /translation="MNAERKFLFACLIFALVIYAIHAFGLFDLLTDLPHLQTLIRQSG
                     LFGYSLYILLFIIATLFLLPGSILVIAGGIVFGPLLGTLLSLIAATLASSCSFLLARW
                     LGRDLLLKYVGHSHTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLSHPKNEG"
     gene            26612..27289
                     /gene="ydjY"
                     /locus_tag="ROH59_000916"
     CDS             26612..27289
                     /gene="ydjY"
                     /locus_tag="ROH59_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416265.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdjY"
                     /protein_id="HDX4803436.1"
                     /translation="MLQHYSVSWKKGLAALCLLAVAGLSGCDQKENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMGYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKITE"
     gene            27303..28010
                     /locus_tag="ROH59_000917"
     CDS             27303..28010
                     /locus_tag="ROH59_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDX4803437.1"
                     /translation="MMKMQSRKIWYYRITLIILLFAVLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGAFWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRNA"
     gene            28010..28558
                     /locus_tag="ROH59_000918"
     CDS             28010..28558
                     /locus_tag="ROH59_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDX4803438.1"
                     /translation="MGLPPLSKIPFILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSTDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRARLATHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPEKRS"
     gene            28568..29734
                     /locus_tag="ROH59_000919"
     CDS             28568..29734
                     /locus_tag="ROH59_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX4803439.1"
                     /translation="MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEVAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTEGAESPWGGAQLTFIARRD
                     VTLQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPTALKEAPDDA
                     TFARVTAPLWQYLDALHPYLWREGKDFPPSPARMDALLKANTLRLSLTFNPAHAQQKI
                     ASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFLLSPDAQLRKADPAV
                     WGDPSVLDPQKLPDGQRETLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH"
     gene            29707..31242
                     /locus_tag="ROH59_000920"
     CDS             29707..31242
                     /locus_tag="ROH59_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4803440.1"
                     /translation="MATPLRYALIFLLWAMIAVIYAPLIPAALTLISPALSLTHWQAL
                     FADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVA
                     FATSALLLFADGGLLYDYFPYFTPPMDKLGIGLGLTLAVKESAFLLWILAAVLSEKRL
                     LQQLIVLDSLGYSRWQCLNWLLLPSVASALAMAMLAIVAWSLSVVDVAIILGPGNPPT
                     LAVISWQWLTQGDADQQTKGALASLLLMLLLAAYVLLGYLLWRGWRRTIPRVDGVRKP
                     ATPLLPSNTLASFLPLTGVLCVVLLAILADQSTINSQALINSLTMGLVAAFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLNLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPALIAFAVGFSVSIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVVKWVGYVRQ
                     GLR"
     gene            31242..31895
                     /locus_tag="ROH59_000921"
     CDS             31242..31895
                     /locus_tag="ROH59_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDX4803441.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAGQFSCTGELWLNEQRIDMLPTAQRQIGILFQDALLFDQFSVGQNLLLALP
                     ATLKGNARRNAVNDALERSGLDGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDNFRHWVFSEIRAMAIPVVQVTHDLQDVPPDSPVLDMAQWSENYNKLR"
     gene            31962..33269
                     /gene="ynjE"
                     /locus_tag="ROH59_000922"
     CDS             31962..33269
                     /gene="ynjE"
                     /locus_tag="ROH59_000922"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YnjE"
                     /protein_id="HDX4803442.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLNEWIKQHNLKADAPVALY
                     GNDKDVDAVKTRLQKAGFTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKFYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPDQQVSFYCGTGWRAS
                     ETFMYARAMGWNNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(33278..33898)
                     /locus_tag="ROH59_000923"
     CDS             complement(33278..33898)
                     /locus_tag="ROH59_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDX4803443.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVAILLNRLLDGLDGALARRRGLTDAGGFLDISLDFLFYALVPFGFIL
                     AAPEQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGSET
                     ILLFVLSCLFPACFPWFAWVFGALCWMTTFTRVWSGYLTLKSLQRQ"
     gene            33985..34392
                     /gene="nudG"
                     /locus_tag="ROH59_000924"
     CDS             33985..34392
                     /gene="nudG"
                     /locus_tag="ROH59_000924"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HDX4803444.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKIEPDES
                     QRQALVRELNEELGIEATVGDYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALRYPLAPADIPLLEAFMASRAARPAD"
     gene            complement(34358..34630)
                     /locus_tag="ROH59_000925"
     CDS             complement(34358..34630)
                     /locus_tag="ROH59_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HDX4803445.1"
                     /translation="MSRALIAVVLAFPLITLANPHYHPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDQNYSEGAVIKAEGILLQCQRDDKTLSTNPLVWRRVKP"
     gene            34866..36209
                     /gene="gdhA"
                     /locus_tag="ROH59_000926"
     CDS             34866..36209
                     /gene="gdhA"
                     /locus_tag="ROH59_000926"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDX4803446.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQVQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLSQGVI"
     gene            complement(36286..38241)
                     /gene="topB"
                     /locus_tag="ROH59_000927"
     CDS             complement(36286..38241)
                     /gene="topB"
                     /locus_tag="ROH59_000927"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDX4803447.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETYKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTSVRQFRGIMAPGGGE
                     GKKKDSPRKRAPKKSPPSEEAGNGVII"
     gene            complement(38246..39289)
                     /gene="selD"
                     /locus_tag="ROH59_000928"
     CDS             complement(38246..39289)
                     /gene="selD"
                     /locus_tag="ROH59_000928"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDX4803448.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGVSFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKATAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            complement(39406..39957)
                     /locus_tag="ROH59_000929"
     CDS             complement(39406..39957)
                     /locus_tag="ROH59_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HDX4803449.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDNKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            40118..41974
                     /gene="sppA"
                     /locus_tag="ROH59_000930"
     CDS             40118..41974
                     /gene="sppA"
                     /locus_tag="ROH59_000930"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707347.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDX4803450.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMNLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRQIPAQQVFPGAQGLLEGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKTLTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEVQQMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANVR"
     gene            42090..42800
                     /locus_tag="ROH59_000931"
     CDS             42090..42800
                     /locus_tag="ROH59_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310500.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HDX4803451.1"
                     /translation="MNKAPSLIAAIVLGLGISACGYFVGDGVKHLKTNNRYVNVRGLS
                     EKEVRADTAELTIAINFKGNIPGELFPKLEDAQKKIVAELNAQGINEKEITLGQWTSK
                     RTDSFYLKDDPTMPRYNADGSVTIKTHNVAAVEKVVAKLNELQVATEGAIAESKVAYR
                     FNGIGALRAEMIAAATKDARNAALQFATDSGSQVGSISDASQGVFQIFASGSDEDDPT
                     AINKTVRVVTTVTYALQD"
     gene            42932..43948
                     /gene="ansA"
                     /locus_tag="ROH59_000932"
     CDS             42932..43948
                     /gene="ansA"
                     /locus_tag="ROH59_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDX4803452.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLSKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQKLDTETIRKAMSQNLRGEL
                     TPDD"
     gene            43959..44600
                     /gene="pncA"
                     /locus_tag="ROH59_000933"
     CDS             43959..44600
                     /gene="pncA"
                     /locus_tag="ROH59_000933"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001587135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /protein_id="HDX4803453.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQE"
     gene            complement(44693..46051)
                     /locus_tag="ROH59_000934"
     CDS             complement(44693..46051)
                     /locus_tag="ROH59_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803454.1"
                     /translation="MEQYDQIGARLDRLPLARFHYRIFGIISFSLLLTGFLSYSGNVV
                     LAKLVSNGWSNNFLNAAFTSALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAAT
                     GAAFVPDMYWLIFFRFLMGTGMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPM
                     LSAAIGVVVIAFFSWRIMFLLGGIGILLAWFLSGKYFIESPRWLAGKGRIAGAESQLR
                     EVEQQIEREKSIRLPPLTLNQSNSKVKVIKGTFWLLFKGEMLRRTLVAITVLIAMNIS
                     LYTITVWMPTIFVNSGIDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRLFGSALLI
                     IIAVLGYIYSIQTTEWAILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVN
                     AVGRIVAVFTPYGVAALLTHYGSITVFMVLGVMLVLCALVLSIFGIETRKVSLEEISE
                     VN"
     gene            complement(46169..46927)
                     /locus_tag="ROH59_000935"
     CDS             complement(46169..46927)
                     /locus_tag="ROH59_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4803455.1"
                     /translation="MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLE
                     DEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEKQLIARKALPFVDNKTTMAADSS
                     STVMELLKLLQDRSDLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEI
                     ISRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFV
                     QLADFSHINYIITDKSPGAEWIAFCKDNNIQLVW"
     gene            complement(47064..48044)
                     /gene="ydjG"
                     /locus_tag="ROH59_000936"
     CDS             complement(47064..48044)
                     /gene="ydjG"
                     /locus_tag="ROH59_000936"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent methylglyoxal reductase"
                     /protein_id="HDX4803456.1"
                     /translation="MKKIPLGTADITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILE
                     AHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGD
                     RQLYKNLSPESIREEVEASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNALKAE
                     GKIRAIGAANVDADHIREYLQHGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYS
                     PLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLAL
                     AWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALER"
     gene            complement(48054..49001)
                     /locus_tag="ROH59_000937"
     CDS             complement(48054..49001)
                     /locus_tag="ROH59_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HDX4803457.1"
                     /translation="MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDA
                     INEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLV
                     TEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGRALTEIFTQA
                     KTRQMIICADMIKPRLNETLNDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLA
                     CGVKTVVIKTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNL
                     RECARFANATAAISVLSIGATTGVKNRKLVEQLLEEYEG"
     gene            complement(49006..49842)
                     /locus_tag="ROH59_000938"
     CDS             complement(49006..49842)
                     /locus_tag="ROH59_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDX4803458.1"
                     /translation="MLADIRYWENDATNKHYAIAHFNVWNAEMLMGVIDAAEEAKSPV
                     IISFGTGFVGNTSFEDFSHMMVSMAQKATVPVITHWDHGRSMEIIHNAWTHGMNSLMR
                     DASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAE
                     FVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKT
                     AISLGIAKINIHTELCQAAMVAVKENQDQPFLHLEREVRKAIKERALDKIKLFGSDGK
                     AE"
     gene            complement(49863..50906)
                     /locus_tag="ROH59_000939"
     CDS             complement(49863..50906)
                     /locus_tag="ROH59_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HDX4803459.1"
                     /translation="MKNSKAMLQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVH
                     GFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCL
                     EGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
                     AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLTMAEQLGATVVI
                     NGAKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAI
                     NFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNN
                     KRDIIKGVIKISD"
     gene            complement(50923..52302)
                     /locus_tag="ROH59_000940"
     CDS             complement(50923..52302)
                     /locus_tag="ROH59_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803460.1"
                     /translation="MEQITKPHCGARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGL
                     ILAQLKALGWTDNSTTATFSAITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASM
                     VVGAFSPNMDFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSY
                     PLCSLIAMGLTPLISAEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEA
                     EKVMRSIEEGVIRQTGKPLPPVVIADDGKAPQAVPYSALLTGVLLKRVILGSCVLIAM
                     NVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGAPFGIFIAMLVMDKIPRKTMGVG
                     LLILIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSG
                     LANAVGRISGIAAPYAVAVLLSSYGVTGVFILLGAVSIIVAIAIATIGIETKGVSVES
                     LSIDAVANK"
     gene            complement(52329..53405)
                     /locus_tag="ROH59_000941"
     CDS             complement(52329..53405)
                     /locus_tag="ROH59_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDX4803461.1"
                     /translation="MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMK
                     HYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGD
                     FLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
                     NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVTVRFPVA
                     KELGATAVVNGSTEDVVARCQQICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRV
                     GMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAIKVKPMITHRIGLSQ
                     WREGFDAMVDKTAIKVIMTYDFDE"
     gene            complement(53775..54047)
                     /locus_tag="ROH59_000942"
     CDS             complement(53775..54047)
                     /locus_tag="ROH59_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707337.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HDX4803462.1"
                     /translation="MNLDDIINSMTPEVYQRLSTAVELGKWPDGVTLTEEQKENCLQL
                     VMLWQARHNTEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            complement(54089..54502)
                     /gene="msrB"
                     /locus_tag="ROH59_000943"
     CDS             complement(54089..54502)
                     /gene="msrB"
                     /locus_tag="ROH59_000943"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDX4803463.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            54844..55839
                     /gene="gapA"
                     /locus_tag="ROH59_000944"
     CDS             54844..55839
                     /gene="gapA"
                     /locus_tag="ROH59_000944"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDX4803464.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            55923..56807
                     /locus_tag="ROH59_000945"
     CDS             55923..56807
                     /locus_tag="ROH59_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HDX4803465.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGIPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHREDADGVALTFELTQSEETKKFWPHDFTLLAHFHVGKTCEIDLEAHGEFETT
                     SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKEDVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSVSMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(56858..57712)
                     /gene="yeaE"
                     /locus_tag="ROH59_000946"
     CDS             complement(56858..57712)
                     /gene="yeaE"
                     /locus_tag="ROH59_000946"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HDX4803466.1"
                     /translation="MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALIGLRENVFLVSKVYPWNAGGQKAINACEASLRRL
                     NTDYLDLYLLHWSGSFALEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATVAHVQQNAAVLEVELSSAELVMLDKAYPAPK
                     GKTALDMV"
     gene            complement(57802..58548)
                     /gene="mipA"
                     /locus_tag="ROH59_000947"
     CDS             complement(57802..58548)
                     /gene="mipA"
                     /locus_tag="ROH59_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein MipA"
                     /protein_id="HDX4803467.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            58984..60918
                     /gene="yeaG"
                     /locus_tag="ROH59_000948"
     CDS             58984..60918
                     /gene="yeaG"
                     /locus_tag="ROH59_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HDX4803468.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            61031..62314
                     /locus_tag="ROH59_000949"
     CDS             61031..62314
                     /locus_tag="ROH59_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HDX4803469.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKILPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD"
     gene            62461..63936
                     /locus_tag="ROH59_000950"
     CDS             62461..63936
                     /locus_tag="ROH59_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDX4803470.1"
                     /translation="MIRSTRISLGLFFNYFLSLTKIDLGQNYISLPSIKSSTHIALLF
                     MASMGTQKLKAQGFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNA
                     VIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVIIHKPINGSTLIQTKSNDVS
                     IFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYN
                     ADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLA
                     SLCCNLLLLTLDEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLT
                     NIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQ
                     QSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTI
                     SIGTVFSTGDTHNISLVMTEADKALREAKSEGGNKVIIHHI"
     gene            64117..65607
                     /locus_tag="ROH59_000951"
     CDS             64117..65607
                     /locus_tag="ROH59_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDX4803471.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     RADSSFLYDKYQNQSIAAHVMRALAAEQSEVPPEQRRAICEAFESANNTHGLNLTAHK
                     YQGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            65650..66153
                     /gene="yeaK"
                     /locus_tag="ROH59_000952"
     CDS             65650..66153
                     /gene="yeaK"
                     /locus_tag="ROH59_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HDX4803472.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGANFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
                     VNFRRTA"
     gene            complement(66154..66258)
                     /locus_tag="ROH59_000953"
     CDS             complement(66154..66258)
                     /locus_tag="ROH59_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803473.1"
                     /translation="MNDQMFVETLIITSSFFAIAAVLVLSVLLIERTG"
     gene            66428..66874
                     /locus_tag="ROH59_000954"
     CDS             66428..66874
                     /locus_tag="ROH59_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDX4803474.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            complement(66831..67652)
                     /gene="nimR"
                     /locus_tag="ROH59_000955"
     CDS             complement(66831..67652)
                     /gene="nimR"
                     /locus_tag="ROH59_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NimR"
                     /protein_id="HDX4803475.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVKHSNQVTANAELCFLFIEPSAVTMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPGSSHPKI
                     RTMVEMMAKEPVEWGSLRQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIAGLTTVSPQSAKPDPRQ"
     gene            67749..68930
                     /gene="nimT"
                     /locus_tag="ROH59_000956"
     CDS             67749..68930
                     /gene="nimT"
                     /locus_tag="ROH59_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HDX4803476.1"
                     /translation="MTCSTSLSGKNRIFLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISQGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGDWSVPLMGVAILSLLMAIFGLCAGRDKEI
                     R"
     gene            68985..69332
                     /locus_tag="ROH59_000957"
     CDS             68985..69332
                     /locus_tag="ROH59_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDX4803477.1"
                     /translation="MNIQCKRVYDPAEQSDGYRVLVDRLWPRGIKKTDLALDEWNKEI
                     TPSTELRKAFHGEVVDFATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYSAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(69354..69608)
                     /gene="yoaF"
                     /locus_tag="ROH59_000958"
     CDS             complement(69354..69608)
                     /gene="yoaF"
                     /locus_tag="ROH59_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HDX4803478.1"
                     /translation="MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRDHPAGEK"
     gene            69791..70816
                     /gene="dgcP"
                     /locus_tag="ROH59_000959"
     CDS             69791..70816
                     /gene="dgcP"
                     /locus_tag="ROH59_000959"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HDX4803479.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMHIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENADISSLRERI
                     QQQIRGEYHLGDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     THSALHS"
     gene            70849..70947
                     /locus_tag="ROH59_000960"
     CDS             70849..70947
                     /locus_tag="ROH59_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HDX4803480.1"
                     /translation="MRIGIIFPVVIFITAVVFLAWFFIGGYAAPGA"
     gene            70950..71024
                     /gene="yoaJ"
                     /locus_tag="ROH59_000961"
     CDS             70950..71024
                     /gene="yoaJ"
                     /locus_tag="ROH59_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HDX4803481.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(71083..71331)
                     /locus_tag="ROH59_000962"
     CDS             complement(71083..71331)
                     /locus_tag="ROH59_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDX4803482.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(71479..71661)
                     /locus_tag="ROH59_000963"
     CDS             complement(71479..71661)
                     /locus_tag="ROH59_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HDX4803483.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVN
                     TVRSYDTENEHDVCGW"
     gene            complement(71665..72024)
                     /gene="yeaR"
                     /locus_tag="ROH59_000964"
     CDS             complement(71665..72024)
                     /gene="yeaR"
                     /locus_tag="ROH59_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HDX4803484.1"
                     /translation="MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLS
                     VMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPEKWHNIEAMTDDTYFNIDFFVAP
                     EVLMEGAQQRKVIHNGK"
     gene            complement(72197..72835)
                     /gene="leuE"
                     /locus_tag="ROH59_000965"
     CDS             complement(72197..72835)
                     /gene="leuE"
                     /locus_tag="ROH59_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HDX4803485.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGK
                     NSETKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS"
     gene            complement(72962..73294)
                     /locus_tag="ROH59_000966"
     CDS             complement(72962..73294)
                     /locus_tag="ROH59_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4803486.1"
                     /translation="MSLTPNALDTTTSKYRFLNDDFILCSFIHSTAWRGIFAFGVFPD
                     HVKIDVARLFPASGHLVQVLPEYYQPANVWAVYVSKLSTSAKVRITVEFLRQYFAEHY
                     PNFSLEHA"
BASE COUNT        18478 a        18773 c        17584 g        18481 t
ORIGIN      
        1 ttatttatat atatttatct gcaaattttt aagtaaagct ccaataaatc atattgttaa
       61 tttcttcact ttccgctgat tcggtgccag actgaaatca gcctatagga ggaaatgatg
      121 gtacgtatct atacgttgac acttgcgccc tcactcgata gcgcaacaat taccccgcaa
      181 atttatcccg aaggaaaact gcgctgtacc gcaccggtat tcgaacccgg aggcggcggc
      241 atcaacgtcg cccgcgccat tgcccatctg ggaggcactg ccacagcgat cttcccggcg
      301 ggtggcgcga ccggcgaaca tctggtttca ctgttggcgg atgaaaatgt ccccgtcgct
      361 actgtagaag ccaaagactg gacccggcag aatttacacg tacatgtgga agcaagcggt
      421 gagcagtatc gttttgttat gccaggcgcg gcattaaatg aagatgagtt tcgccagctc
      481 gaagagcaag ttctggaaat tgaatccggg gccatcctgg tcataagcgg aagcctgccg
      541 ccaggtgtga agctggaaaa attaacccaa ctgatttccg ctgcgcaaaa acaagggatc
      601 cgctgcatcg tcgacagttc tggcgaagcg ttaagtgcag cactggcgat tggtaacatc
      661 gagttggtta agcctaacca caaagaactc agtgcgctgg taaatcgcga actcacccag
      721 ccagacgatg tccgcaaagc cgcgcaggaa atcgttaata gcggcaaggc caaacgggtt
      781 gtcgtttccc tgggtccaca aggggcgctg ggcgttgata gtgaaaactg cattcaggtg
      841 gtgccaccac cggtgaaaag ccagagtacc gttggcgctg gtgacagcat ggtcggcgcg
      901 atgacactta aactggcaga aaatgcttct cttgaagaga tggtccgttt tggcgtagct
      961 gcggggagtg cagccacact caaccaggga acacgcctgt gctcccatga cgatacgcaa
     1021 aaaatttacg cttacctttc ccgctaacaa aaacattccc ccagcattgg gggaatcacc
     1081 accaacctgt cggcaacgcg tttctccgac tatgctcaaa agtcatgtga taacaaaggg
     1141 gtgaactatg gccagtggcg atcttgtccg ttatgtaata accgtcatgt tgcatgagga
     1201 tacattgact gaaattaacg agttgaataa ttacctgact cgcgacggtt ttttgctcac
     1261 catgacagat gatgatggca atatccatga gctggggact aacacttttg gacttatcag
     1321 tacccaaagt gaagaagaaa ttagagaact ggtttcgggg cttacccaca gtgcaaccgg
     1381 caaagatcct gaaatcacca tcacgacctg ggaggaatgg aatagcaaca gaaaataaat
     1441 ggtttttggg caataatcag tctgtggtgt gcgttagctc gtgtttttac accgcattct
     1501 tgcgctaacc ttatgatctg gcagacaaca tgggagagac atcatgtggc aggcaatcag
     1561 tcgtcttttg agcgagcagt taggtgaagg cgaaatagaa ctgcgtaatg aactgcctgg
     1621 cggagaagtc catgccgcat ggcatttgcg ctatgcagga cgtgactttt tcgtcaaatg
     1681 tgatgaaagg gaactgcttc ccggttttac cgccgaagcc gaccaactgg agttactgtc
     1741 gcgtagtaaa accgtcaccg tgcctaaggt ttgggcagtt ggcgctgacc gtgactacag
     1801 ttttctggtg atggattatc tcccacctcg cccgctggat gcgcatagtg catttattct
     1861 tggtcagcaa attgcgcgtt tacatcaatg gagcgaccaa ccacaatttg gcctcgattt
     1921 cgataacgcg ctctccacaa ctccacagcc caacacctgg caacgtcgct ggtcaacttt
     1981 ttttgctgaa caacggattg gctggcagct ggaactggcg gcagaaaaag ggatcgcttt
     2041 cggcaatatc gatgccatcg tcgagcatat tcagcagcgt cttgcctcgc atcaaccgca
     2101 gccttctctg ttgcacggcg atttatggtc cggcaactgt gcgctgggtc cggatggccc
     2161 gtacattttc gacccggcct gttactgggg tgaccgagag tgcgacctgg cgatgttacc
     2221 gctgcatact gaacagccgc cacaaatcta tgacggctat cagtcagtat ccccgctacc
     2281 tgccgatttc cttgaacgtc aaccggttta ccaactctac acgctgttaa atcgtgcaag
     2341 gttatttggc ggtcagcatt tggttattgc tcagcagtca ctggatagat tattagcagc
     2401 atgatatggg ttgaggataa tggccgctcc gtgcggcctt ttgattaaat aaacccaagc
     2461 agagaaaaga acacataacc tgcagcaata caaataaccg gcaggatata cagcgagaaa
     2521 aactgcagga aaatagtatg gtgcggaaca acaatacgtg actcaatttg ttcacgcgtt
     2581 agcccctctt cccctttggc tttttccaga atgagttgat cttcaacacc ttcccgcaag
     2641 aagcgcgcct ggcgactcat ccgggctccg gaatcctgca acgccagtcc gacaaaaatc
     2701 aggatgaaaa tcacccagaa cataacgttc acgccaccat taaaattggg cgtcggagag
     2761 ttgtaccaga acagattcaa aaaaggcgta ttcgcctgca tcatatcgat catgacatga
     2821 gtaaagtcga gcatgaccgc attaatgcct tcctggtttt cctgccgggt attcataaat
     2881 ttcagcaaag aaatcaatgt agagatcaat gcaggtataa aaatcaccca acccaaaatc
     2941 cttttcaaaa cagcaatgcg tccagcttgt tgatacgtca tgagttctcc ttgattaaga
     3001 cgcgtcgttt cacttagttt acctgtagat atctgttttc gcccattctt taaaggcgat
     3061 atgataggcg cttaatcata agcacggctt aataccttac atataatgct ctaaaggaga
     3121 ggttgtaatg tcaaccccgc gtcagattct tgctgcaatt tttgatatgg atggattact
     3181 tatcgactca gaacctttat gggatcgagc cgaactggat gtgatggcaa gcctgggggt
     3241 ggatatctcc cgtcgtaacg agctgccgga caccttaggt ttacgcatcg atatggtggt
     3301 cgatctttgg tacgcccggc aaccatggaa tgggccaagc cgtcaggaag tagtagaaca
     3361 agttattgcc cgtgccattt cactggttga agagacacgt ccattattgc caggtgtgcg
     3421 tgaagccgtt gcgttatgca aagaacaagg tttattggtg gggctggcct ccgcgtcacc
     3481 gctgcatatg ctggaaaaag tattgaccat gtttgattta cgcgacagtt tcgatgccct
     3541 cgcctcggct gaaaaactgc cttacagcaa gccgcatccg caagtatatc ttgactgcgc
     3601 agcaaaactg ggggttgacc ctctgacctg cgtggcactg gaagattcgg taaatggcat
     3661 gatcgcctct aaagcagccc gcatgcgttc catcgtcgtt cctgcgccag aagcgcaaaa
     3721 tgatccacgt tttgtattag caaacgtcaa actctcatcg ctgacagaac tcaccgcaaa
     3781 agaccttctc ggttaatgac cagggggcag tgatcacact gcccctggtt ctttatctga
     3841 atttgcattc aaatgacgga ttaatcgcca atttaagaga aagagttaca ccgtcaccac
     3901 ttccgtgcac tgtataaaaa ccctatactg tacgtatcga cagtttagtg agttttatca
     3961 tgacggcgga aggtcacctt ctcttttcta ttgcttgtgc ggtatttgcc aaaaatgccg
     4021 agctgacgcc cgtgctggca cagggggact ggtggcatat tgtcccttcc gcaatcctga
     4081 cgtgtttgtt accggacatc gatcacccaa agtcgtttct tgggcagcga ttaaagtgga
     4141 tatcaaaacc gatcgcccgc gcttttgggc atcgtggttt tacccacagc ctgctggcgg
     4201 tatttgcgct gctggcaacc ttttacctta aggttcctga aagctggttc attccggctg
     4261 atgcgttgca gggtatggtg ctgggttatt tgagccacat acttgccgat atgctgacac
     4321 ccgccggtgt tcccctgctc tggccatgcc gctggcgttt ccgcttgcct atcctggttc
     4381 cccaaaaggg caaccaactg gaacgtttta tctgcatggc attatttgtc tggtcggtat
     4441 ggatgcccca ttcattaccc gaaaacagcg ctgttcgttg gtcatcgcaa atgatcaata
     4501 ccttacagat ccagtttcat cggcttatta agcatcaggt tgaatactaa aaaggcaaaa
     4561 atcgcctttc tggaataagc aattccattt gaatataaga gccagctcac agttctgtta
     4621 atcttgcgcc aacactatga ctgctacgca gtgatagaaa taataagatc aggagaacgg
     4681 ggatgaactt tccattaatt gcgaacatcg tggtgttcgt tgtactgctg tttgcgctgg
     4741 ctcaaacccg ccacaaacag tggagtctgg cgaaaaaagt gctggtgggt cttgtgatgg
     4801 gtgtggtttt tggccttgcc ctgcatacca tttatggttc tgacagccag gtacttaaag
     4861 attctgtaca gtggtttaac attgttggta acggctatgt tcaactgctg caaatgatcg
     4921 ttatgccgct agtcttcgcc tctattctga gcgcggttgc ccgtctgcat aacgcatctc
     4981 agttaggcaa aatcagtttt ctgaccatcg gtacgctttt gtttaccacg ctgattgcag
     5041 cgctggttgg tgtgctggtc accaacctgt ttggtttgac ggctgaaggt ctggttcagg
     5101 gtggtgcaga aactgcacgt ctgaacgcca tcgaaagtaa ctatgttggt aaagtctctg
     5161 acctgagcgt tccgcagctg gtcttgtcct ttatcccgaa aaacccgttt gccgatctga
     5221 ccggagccaa tccgacgtca attatcagcg tggtaatttt tgccgcattc ctcggcgtag
     5281 ctgcgctgaa actgctgaag gatgatgcgc cgaaaggtga acgcgtctta accgctatcg
     5341 ataccctgca aagctgggtg atgaaactgg ttcgcctggt catgcagttg accccttacg
     5401 gtgttctggc gctgatgacc aaagtggttg caggttctaa cctgcaagac atcatcaaac
     5461 tgggaagttt cgttgtcgcg tcctacctcg gtctgctgat tatgtttgca gtgcatggcc
     5521 ttctgctggg cattaatggc gtgagcccgc tgaagtactt ccgtaaggta tggccagtac
     5581 tgacgtttgc ctttaccagc cgttccagtg ctgcgtctat cccactgaat gtggaagcac
     5641 aaacgcgtcg tctgggtgtt cctgaatcca tcgccagttt cgccgcctct ttcggtgcga
     5701 ccattggtca gaacggttgt gccggtttgt atccggcaat gctggcggtg atggttgcgc
     5761 ctacggtggg cattaacccg ctggacccga tgtggattgc gacgctggtc ggtattgtca
     5821 ccgttagttc cgcaggcgtt gccggtgtcg gtggtggtgc aactttcgcc gcactgattg
     5881 tgctgcctgc gatgggcctg ccggtaacac tggtggcatt gttaatctcc gttgaaccgc
     5941 ttatcgacat gggccgtacg gcgctaaacg ttagtggctc gatgaccgct ggcacgctga
     6001 ccagccagtg gctgaagcaa accgataaag ccattctgga tagcgaagac gacgccgaac
     6061 tggcacaccg ttaatcctga tttgttacgt taaacgcctg tcatcccgac aggtgttttt
     6121 ttattcttcg acctcatttt cctggcggat ctgatttgcc caacgctggg cggattcagg
     6181 cacagtaaac gccggtgagc gcagaaatga ctcccccatc agtacaaacg caacatattt
     6241 gccacgcagc atccagacat ctcgaaacga atccatcttt atcgcatgtt ctggcggcgc
     6301 gggttccgtg cgtgggacat agctaataat ctggcggttt tgctgacgga gcggtttctt
     6361 cattactggc ttcactaaac gcatattaaa aatcagaaaa actgtagttt agccgattta
     6421 gcccctgtac gtcccgcttt gcgtgtattt cataacaccg tttccagaat agtttccgaa
     6481 gcgggatctg gctggtggtc tatagttaga gggttttttg accaaaacag cggccctttc
     6541 agtaataatt taaggagacg agttcaatgt cgcaacataa cgaaaagaac ccacatcagc
     6601 accagtcacc actacacgat tccagcgaag cgaaaccggg gatggactca ctggcacctg
     6661 aagacggatc tcatcgtcca gcggctgaac caacaccgcc tggtgcacaa cctaccgccc
     6721 cagggagcct gaaagcccct gatacgcgta acgaaaaact taattctctg gaagacgtac
     6781 gcaaaggcag tgaaaattat gcgctgacca ctaatcaggg cgtgcgcatc gccgacgatc
     6841 aaaactcact gcgtgccggt agccgtggtc caactctgct ggaagatttt attctgcgcg
     6901 agaaaatcac tcactttgac catgagcgca tcccggaacg tattgttcat gcacgcggat
     6961 cagcagctca cggttatttc cagccatata aaagcttaag cgatatcacc aaagcggatt
     7021 tcctctcaga tacgaacaaa atcaccccag tatttgttag gttctctacc gttcagggcg
     7081 gcgctggctc tgccgatacc gtgcgtgata tccgtggctt tgccaccaag ttctatactg
     7141 aagagggtat ttttgacctc gttggcaata acacgccaat cttctttatc caggatgcgc
     7201 ataaattccc cgattttgtt catgcggtaa aaccagaacc gcactgggca gttccacaag
     7261 ggcaaagtgc ccacgatact ttctgggatt atgtttctct gcaacctgaa actctgcaca
     7321 acgtgatgtg ggcaatgtcg gatcgcggta tcccgcgcag ttaccgcact atggaaggct
     7381 tcggtattca taccttccgc ctgattaatg ccgaagggaa ggcaacgttc gtacgtttcc
     7441 actggaaacc actggcaggt aaagcctcac tcgtttggga tgaagcacaa aaactaaccg
     7501 gacgtgaccc ggacttccac cgccgcgagt tgtgggaagc gattgaagca ggcgattttc
     7561 ctgaatacga actgggcttc cagttgattc ctgaagaaga cgaattcaag ttcgacttcg
     7621 atcttctcga tccaaccaaa cttatcccgg aagaattggt gcccgttcag cgtgtcggca
     7681 aaatggtgct caatcgtaat ccggataact tctttgctga aaacgaacag gtggctttcc
     7741 atccagggca tattgtcccc ggtctggatt tcaccaacga cccgttattg caggggcgtt
     7801 tgttctctta taccgataca caaatcagtc gtcttggtgg gccgaatttc catgaaattc
     7861 cgattaaccg cccgacctgc ccttaccata atttccagcg tgacggcatg catcgtatgg
     7921 ggatcgacac taacccggcg aattacgaac cgaactcgat caacgataac tggccgcgcg
     7981 aaacaccgcc ggggccaaaa cgtggcggtt ttgaatcata ccaggaacgc gtggaaggca
     8041 ataaagttcg cgagcgcagt ccatcgtttg gcgaatatta ttcccatccg cgtctgttct
     8101 ggctaagtca gacgccattc gagcatcgcc atattgtcga tggtttcagt tttgagttaa
     8161 gcaaagtagt tcggccgtat attcgtgagc gcgttgttga ccagctggcg catattgatc
     8221 tcactctggc ccaggcggtg gcgaaaaatc tcggtatcga actgactgac gaccagttga
     8281 atatcacccc gcctccgaac gtcaacggtc tgaaaaagga tccatcctta agtctgtacg
     8341 ccattcctga cggtgatgtg aaaggtcgcg tggtagcaat tttgcttaat gatgaagtga
     8401 gatcggcaga ccttctggcc attctcaagg cgctgaaggc caaaggcgtt catgccaaac
     8461 tgctctactc gcgaatgggg gaagtgactg cggatgacgg tacggtgttg cctatagctg
     8521 ctacctttgc cggtgcgcct tcgctgacgg tcgatgcagt cattgtccct tgcggcaata
     8581 ttgcggatat cgctaacaac ggcgatgcca actactatct gatggaagcc tacaaacacc
     8641 ttaaaccgat tgcgctggca ggagacgcgc gcaagtttaa agcaacaatc aaggtcgctg
     8701 accagggtga agaagggatt gcggaagctg accgcgccga tggtagtttt atggatgaac
     8761 tgttaacgct gatgacagca caccgcgtgt ggtcacgcat tcctaagatt gacaaaatcc
     8821 cggcgtaaat atggataagg tcacgccccc tggggagtga ccttaccacc ttacttacac
     8881 atcatgataa ctacccaacc gataaccacg ctcagcaatc gcatatttca acgacgctga
     8941 agtcagcaca tccagttccg ttaaccgagg gaagcaataa gcactctggc gaatcgtatt
     9001 atcgataaac gccgggtggc acatcacttc cagcgagcgc tcgccgcgat gactggagtc
     9061 atcaagcact tgcaggaaca gtgtctcgct aatctcttca ccataaaacg cgctactgaa
     9121 tccctgcgaa ctgcgcagat tagccggtaa atcaccatcc ttagaaagcg actgacggtc
     9181 gatgcgcaac gcaatcccct cttcagccgc aaactttgcc acaatcggga aaatctgcgg
     9241 gaacatatgc acatgatgat ggctatcaag atgcgtaggt ttgcgtccaa atagctcaat
     9301 gaaacgcaaa tactgactgg cgagctcctg agtaatttct tccagcggta aagcatcttc
     9361 ttctgccaac tgccagatcc attttcccag cacaccatcg cgggttaacc ccggcatagc
     9421 tgtcagaggc ttgcccatag taaggacaaa gtgcatccct atggccagac tcggttcatc
     9481 acggctcaac tgcaccgcat ggtcaatagc ctgcccattc accagcgccg tcgtcgacgt
     9541 gacaatccca ttgcgacagg cctcgataat gccgtagttc tgacctttgc ttaagccaaa
     9601 atcatcagca ttaacaatca gtaagcgttc cataatcagc ctcggttaat gtgctttttt
     9661 aagctctgcg atgcagtcgg caaaatttgg cagccatttc tcgtgcgcca gaatcatctc
     9721 gcgtgccagc agctcagcat cgcgatcgga atgcaccaac ggactaaggt ttagcgccag
     9781 taagacatcg ttaaattctc cactaagtgc ggcgttgctg gcagcaatct cgaagccttt
     9841 gatggtgtga atcagcccca tcactttatc atcgaaatgc gtaatgcgcg gatgtggcgt
     9901 cgcgccatcg cgccccagcg tacaggtcat ttctaccgcc cagtctgccg gaatattatc
     9961 aatatgccca tgatgcggga tattaacgta atgttctgct tgcttgtcgt tatagatagc
    10021 gttgatcact tcgcacgcag catcagaata ataagcccca ccgcgctgtt ccagttcttt
    10081 cggcttaact ttcaactccg ggtttttata tagctcaaaa agttgtttct cgactttctg
    10141 tacgacctgc gctcgtgcgc cgcctttgta gtattcgccc atttcaatag ccagcatctc
    10201 tttttgcttg aagtaataaa gcaaataaga acacggcaac agattcagag aacgaattaa
    10261 gccttcgcta aatggcagat cgaaaatatt tttaacgcca gatgctttta actgcccgga
    10321 tgccacacca tcaagcaatt cggcaaagcg tgatttgcca tttaccagca catccttaat
    10381 gaacaccata tggttgaggc cgaacagatc gatagataaa tcatcgctgt ctttcagcat
    10441 cagaacatcg cgaataaaca tcttcatgcc gatcggaata ttacacacgc cgataaagcg
    10501 tttaaatccg gtatgacgat aaacggcttc agtgaccatt cccgccgggt tagtgaagtt
    10561 aatcacccat gcattcggac atagttcttc gacatctttt acgatgtcaa aaatcaccgg
    10621 aatggtacgc agacctttaa acagaccgcc cgcgccgtta gtttcctgac caagataacc
    10681 atgacttaat ggaatacgtt catccagttc ccgcgccggt aattggccaa cgcgcagttg
    10741 ggtagtaacg aaatcagcat ctttcaatgc ttcgcggcga tccagcgttt tataaagctt
    10801 catcgggacg ccagcgttat caatcatccg ttggcagaga tcaaaaataa tatccagttt
    10861 cgctttacca ccttcgacat ccaccagcca taattcgctg accggcaatt cgtgataacg
    10921 cttaataaat ccttccagta actccggggt atagctgctc ccgccaccaa tagtgacgac
    10981 ttttaatttc tggctcataa tttctccctt cagtacagaa tactgatatc tggcatatct
    11041 gcccccggac ataaataatc cagcaacagg acagatatgt gaattgtcag gtataacgac
    11101 ttactgatta aattcagtca atttcttacg atagctctta ggcgtaaagg acgttaattt
    11161 cttaaacgtt ttaataaaca agctcgggct actataaccg gcctcaaacg caatatccgt
    11221 cactgaatag ttggtcattt ccagttgttt tttggcaaaa ttaatacgga tttcattaat
    11281 aatctgcatt ggcgttttac cataatatcg ttgagtcgct cgcgtcaaat attcctgtga
    11341 tttggctgac aacgtcacca tattctccag cgccgattca ctaaactgct ctttatcatg
    11401 cattttttct accgtacttt tcagccactg cggtatatca tcaatcacct gttcttcgcg
    11461 gtaatgacgt aaacggttaa tgacataaaa agtaaccatc tcaacaaact cttccagccc
    11521 tgtttcgcgg aaattcaatg aagaaatcac tgtttccaca taggtgagaa aagcgttatt
    11581 ggtccggtat acctgcgaag ctacaaagca ataaggcaac aacggcaggt aatgctgctc
    11641 aaaaaagcgt ttactgatcc caacgttcaa tatacgcgtg gcaccaaact cataaaaact
    11701 ttgatggtgc gaacctaacg gaataaaaac aaaatcgccc cgttccagta acacgcgctt
    11761 accgttaatc tcctggaaat aacgcccggt taataccaga gtaaattcat aatagtcgtg
    11821 ctgatgcagt ccgctgatac tctcagtttt attatagata aacacatgga agtttttgcc
    11881 attaaacaac tgctgttctc gggcagtggc aatttccggc gcgttaatca ctggctgcat
    11941 catcgactcc ttatgccttc agtttttcat gaagctcaat taattcagta atcagttcac
    12001 gcgcaagcat ggacgtcatt aaatgatcct gagcgtggac cagcaccaga ctcactttca
    12061 tcttaccttc gccagcatcg ccttcaatca gtttcgtctg taccagatgc gcttcattca
    12121 atgccatccg tgactgatcc atcatcgctt ttgctgcggc aaaatcgccc tgcttcgcct
    12181 gtttcagtgc cgcatacgcc aggctacgcg cttgtccgga gttgatgata agccccatca
    12241 ccacttcttc cagctcttca gcttccgttt gcgtatcggg aatattatcg agatccatca
    12301 tacatcgttc ctctctattc ttaccggcac gattacccgt accggcatcg attaaaattt
    12361 cagggcgtta gcgatatctt cttcgctctc ttctttatca atcgcgtttt gtgctttgtt
    12421 agcgaccaca acaaagggca gataaattaa cgttgcgata ccaaggttga agagtgcgac
    12481 cagcaatgcg gcgacgctac cgttggtgtt aaagaaggct cccagaccgg ttggcatggt
    12541 ccacggtgca atattggtca ccggtggaat aatgcccatg tagtacgctg ccagggtgat
    12601 tgccgccaga atcggttgta ccagtacaaa cgggataaac atcaccgggt tcatgataat
    12661 tggcagacca aacagaatcg gttcgttaat ctggaagatg ccagacggca gcgccagttt
    12721 tgccacctga cgataatcag cacgtcgaga ggcgataaag atagccagga tcaggcctaa
    12781 agtcgcacca ctgccaccaa ggaaaataaa ggagtccagc atcggcttgg cccagatatg
    12841 gaaggtctta ccggctgcca gcgccgcttc gacggaacca tattgctgat aggtcgcgat
    12901 attttccagc gcccaaggcg tcataatgcc gttgtccagt gcggtcagcg ccagcgcgcc
    12961 atgaataccg aagaaccaga gcagtggaac aaagatcaca taggcccagc ctaccacgct
    13021 acccaacgat gccagtgggg ttgagatcgt atccataatg atctgatgga agttggtgcc
    13081 ccaggtattc aacgcccagg caataatccc catcacggaa agaataataa aaccaggaat
    13141 taatgctgag aaagagcgcg aaaccgatgt cggaacgcta tcaggtaact taatgaccca
    13201 gttacgatga acaataaagg taaacatttc tgccaccacc aggccaataa taatcccgga
    13261 gatgatattc gccccaccta accagtttgc gccaaccgca taggcctcac cgacactata
    13321 tggggtgacg gtcataaatg ctgcaacgga taacaacccg gccgccagcg catcgacttt
    13381 acgctcttct gccagcgcca tgccaataaa gaacggtgcc attaaagaca ttatccctaa
    13441 tgttccgtta tatacgttgc cgccaatacc tttcagacca ttaagtgttt caatggttga
    13501 ggcatccagg cgaataccta aggaataaaa aaacgacccc tccccaaagc ttagaaaaac
    13561 gttgttaatt aatacaaaca tggcccccgc aagggttaac ggcattaagc gaataaagcc
    13621 atttttgatt gcattaacgt gtggctgctt tcctatttta actgcaaaag ggaggagtac
    13681 cttttcaagc gatgcaataa cattactcat agaaaaatac ccttaaaaac cgcaatttaa
    13741 atattgcggt attgatttat gaaataactc tttgacggga aaatttaaaa taaattaatt
    13801 tgctgcggct tttttaatcg ctgcaaccgc agccttaagc acgcctaaac catcgacttt
    13861 gccataaagc agcgagtcaa ttacttcaac cggtttgttg ggtaacaaac gctggatttc
    13921 gggcaacata taagcaatct gcggccctaa taacacgaca tcggcattct gacctttttc
    13981 accagccagt gtttccggaa atgcttcaat aatgaccgga acttcatatt tttctgcctg
    14041 tgcgcgcatt tttgatacca gtaaagaggt agacatgccc gcagaacaaa acagataaat
    14101 gtgtttcttt tccataaaac tgccctcatc gacgattatc tgtcagccag acactccgca
    14161 agccttaacc tgcttccatg ctctgggtaa cttgcgaaac caacatgact ttttttgtgg
    14221 ctgaaaggag tatacggtat aggcctgagc aatagtattt ctttgacctg ataaattgtc
    14281 tctccttgac ctgtggttat gaccctcttc acatttcggg caaataattc gcgaagataa
    14341 ttaagaacac aggccaaaaa aaaccggcgc aatggccggt ttccgttgtt actcaagctt
    14401 tcaggcgaag tgattacttc gtagcctgcg gatcagtgtc gtattcagca caggtctgat
    14461 aaccggagtt gatgacatgt ccggtatcat ctaacgcgac aaagtaggtt tctgctttac
    14521 catcacgttg acccaggatg taggtctggc aagtaccacg agcatggatc atgctcactt
    14581 cagacgaagg tttacccgca atttgtgcaa cctgcgcccg gctcatgcct tttttgacgt
    14641 ctttcaccac aggctgtaca aactggtctt tggtacgatc ataagccgta caacccgcca
    14701 gcatggttaa taccgccgct gcactcagaa ttcctgccat attcttgttc atattccgtc
    14761 ctcttgttta tcagcgtgtt agataagcct ggaatacatt gggcgctttt tcaagcccgt
    14821 gaacgaaacg gctccgcttt cagaggattc ctgtatgacg ttttaaccac cattcagccc
    14881 gctgtcgctt gtcgtttcag tagcaacggg ttagctttaa ggaagttttg tcttttctgt
    14941 ctggaggggt tcaatgacat tgcaacaaca aataataaag gcgctgggcg caaaaccgca
    15001 gattaatgct gaagaggaaa ttcgtcgtag tatcgatttt ctgaaaagct acctgcaaac
    15061 ttatccgttc attaaatcac tggtgctcgg gatcagcggc ggtcaggact ccacgcttgc
    15121 cggtaagctg tgccagatgg cgattaatga gctgcgccag gaaaccggca acgaatcact
    15181 gcaatttatt gccatacgcc tgccctatgg tgtccaggct gacgaacaag attgccagga
    15241 tgccattgcc tttattcaac cggatcgcgt attaaccgtt aatatcaagg gcgcggtact
    15301 cgccagcgaa caggcgctgc gcgaagcggg cattgaactg agcgattttg tccgtggcaa
    15361 tgaaaaagcg cgtgagcgga tgaaagcaca atatagcatt gcgggtatga ccagtggtgt
    15421 cgtggtgggc accgatcatg cagcagaagc tattaccgga ttcttcacta aatatggtga
    15481 cggcggtacg gacattaatc cgctgtatcg tctcaacaaa cgtcagggta aacagttact
    15541 ggcggcatta ggttgcccgg aacaccttta taagaaagcg ccaacggccg atcttgaaga
    15601 tgatcgccct tctctaccag atgaagtggc actcggcgtg acctatgaca atatcgacga
    15661 ctatctggaa gggaaaaacg tacctgaaca ggtcgccaga acaatagaga actggtatct
    15721 gaaaaccgaa cataaacgcc gtccgccaat taccgttttc gatgatttct ggaaaaagta
    15781 ataatttgca cctattggat tgtgcgaaaa agagtaattt gttcacgccg gatgcggcgt
    15841 gaacgcctta ctcgacctac aaaactatgc aaattcaata cattgcagga gtcgaatagg
    15901 cctgacaggc gtagcacgtc agacggtgta acctttgtca tcaacccgcc tcttttttaa
    15961 tcgctccccg cctgttacac tggatagata accagcattc ggagtcaaca gtggtacggc
    16021 gtttaacttc tccgcggctc gaatttgaag ctgcggcaat ttatgaatat cccgaacatt
    16081 tacgttcatt ccttaatgac ttacccaccc gaccaggggt gtatctgttt catggcgaaa
    16141 gtgacaccat gccgctctat atcggcaaaa gcgttaatat ccgcagtcgg gtgctttctc
    16201 atttacgcac cccggatgaa gccgccatgc tgcgacaatc ccgacgcatc agctggatat
    16261 gtaccgccgg tgaaatcggc gctctactcc ttgaagcgcg attaatcaaa gagcagcagc
    16321 cgctgtttaa taaacgcttg cgccgcaatc gccagctctg cgccctgcaa ttaaatgaaa
    16381 agcgtgttga tgtggtgtat gccaaagagg tggatttttc acgagcctcc aacctgtttg
    16441 gcctgtttgc caataggcgc gcagctttgc aagcattgca gaccatcgcc gatgaacaaa
    16501 aactttgtta tggcctgttg ggactggaac cgttaagccg cggtcgtgca tgttttcgtt
    16561 ctgcattaaa acgttgcgcc ggggcgtgtt gcggtaaaga gagccatgag gaacatgcgc
    16621 tacgcttgcg ccaggctctg gagcgtttgc gggtggtgtg ttggccttgg caaggcgcgg
    16681 tggcattgaa agaacagcac ccggaaatga ctcaatatca tattattcaa aactggctgt
    16741 ggctgggggc ggttaattcg ctgaaagaag cgacaacgtt aattcgggca cccgccgggt
    16801 ttgatcacga cggttataaa attctttgta agccgctgct ttccggtaac tatgaaatta
    16861 ctgaacttga tccggtgaat gaccagcaag ccagttgatt tcactgaaca acagtttacc
    16921 ttgcggttgc aaaagccgca gggtgtgcct gccatcgaac cagcacgcgc cctggtcggt
    16981 agtgagcagt ttgtcgccca attgccacgc cccgtttatt acaaacacca ccccgccgcg
    17041 tgaaccaaag gtggtaaacg tacgttcggc aattctgact ttcgccttac agacatccag
    17101 gcgtgtcatg atgttgaaat ccatcgacat ctgccctgcc gtcagtttcg cttttaccac
    17161 cagatccgct gcaaaggaaa aaggttgtaa cggttttaag gtatggttaa agcggtctgc
    17221 gctttcaagg aacatctcgc cgccttccag caacgtcact atcctttcca taccgggaaa
    17281 caaagaaaac tccccattcg ccgcgatgga tgtaatgctg gcacgccagt aaaaatcacg
    17341 ttttgccggt gggaaagtgc aaatttcgcg cgtttcaccg gcagcgtttc gccacagatt
    17401 caccgacatt ttacgcatat caaagtattc catacccgct cccggcccgt tcttttcatt
    17461 gttatcgttc aggtaaccgt ggatggttat cggcaactcg ggtgatttac gttagtggcg
    17521 atcaggcttt ttttgcatct gtttgagaag agaaaagaaa accgccgatc ctgtccaccg
    17581 cattactgca aggtagtgga caagaccggc ggtcttacgt tttttggctg aaagattatt
    17641 cagcagttgc aggcatttta ccttttgccg ctggacgttc tgtcagacgc ttctcaaaat
    17701 tagcattaaa ttgctttttc tgttccggcg tcaggatgtt gtaaatcttg ttctgggttt
    17761 ccatgtgcgc cagcatgtta gctttgcgct gttcttccat ttttgcgatc tgcgcttcag
    17821 cttttgcttt atcgaaggta tcgctggcaa tgatgtcatg cattgcgcgg cgttcttcca
    17881 gtggcggacg tttcatctgg tcacgctggc ctttcatgat ttcgcggatc tgctgtttct
    17941 gcgcgtcggt caggttcagg tctttgaaca tcatgtcctc atgcggaccg aacttgcctt
    18001 tatggtgcat catcggcttc gcgtcagccg gtgctgcagt agtggtgtct gcggcatggg
    18061 ccaggttagc cgcgccaaga gccagggtag aggcaacaaa cagtgcagtt aatttacgca
    18121 tattctatat ccttcctttc agttatttat tacggctttc ttaagtagcg tgccgtgttg
    18181 acgagattaa ctttactgac tttagcgtca attaatcaga gcaacggtaa aacaatgaaa
    18241 gtgtaaaaaa cacttttgcg ccaattatgg agaaaaaaag aaaatttgat ggagagtgat
    18301 gagagaatat tacaacacga tgattttgca gagattatga agaactatac cggatgactg
    18361 gtgataaata aagcaaataa ccaggattaa tctgtattaa tttataagaa agcaacttaa
    18421 tacccgcaga atgatttctg cgggtaagta ttagcttatt ttttcgagca ttaatcccgc
    18481 acgtaatccc aacgctacca acggattagg gaataacaca tactctacat catgggttac
    18541 ggtaaaacgt tcctccccgt cctgcgccag caatgttcct ttctcaaacg gcataaaatt
    18601 cagcgtgtca tttgccatat gcatttcgaa ggacggcgag tggcgagtaa tttgcgaaac
    18661 cacccgataa cggagcggcg gtgttctcac gataccgaca ctctcaccag atagcagcgc
    18721 agcaattgcg ctggcagtta ctgcaaactg gcgaagatcg ttttgtccaa agggcaacgc
    18781 tttgccgagt tccagcgtac aggccagcgc gccaaaatgt ctggcgctga aatgggtaaa
    18841 cgtaccacca ggctcctgat ggaacaccag tgcctccaga cccgccgcac ccagccacgt
    18901 cagaaatttc tcgtcccagg gaatgtcgcg ttgcggtaat acaccgaacc gcggatgcaa
    18961 ggagccacga attgcggtat ggagatcaag gtgccagcgc acagattctt tgccctggtc
    19021 ataaaaatct tccaggcact gttccagttc gcgcgcccga caggtttccc cgctttcagc
    19081 aaatagctgc caacgaccgc caaacattcg gttcatatcg ctatggcaat aacgtttccc
    19141 ttgcttcagc gcaggaggat tcccgaggat caccagcaac cgccaacgta acgggatctc
    19201 gccgtgagat atcgcgccaa gcaacgcatc cagcatttcc acaggtgccg tctcattacc
    19261 gtgtattccc gctgaaatca ccagtgcgcc ttgcggtggc gttaatggcg tcagttccag
    19321 cacgccatcg cccagccagc gccagcgaac gccgttgatt tctcgctcgg tgataaccgg
    19381 ttttttaccc gttaaggtca gagcaagaaa attatccatt tccccctccc tcgcgctgga
    19441 atggataaac cgaaccaaga tccaataatt gagtcagtgt atccagcgct tcccgtcctt
    19501 cgcgcagcaa ttgtggatcg gcaagatccg ccgcagtaag acgatcgcgg tagtaacgat
    19561 ccacccagtc attgagcgca ttaaacagcg tatcgttcat catcaccgcc ggattcaccg
    19621 cccggcgttc ttcttctgtc aacaccacgc gcagccgcag gcacgccggg ccaccgccat
    19681 tcgccatgct ttcacgtaaa tcaaaaactt ttagtgagct tattgggtta tcggcagcaa
    19741 gcaattcatt gagataacac catactccag catgttcccg acattcctga ggcagcacca
    19801 acatcatgga accatcatcg cggctcagca gttggctgtt aaacagataa gtagacaccg
    19861 catctgacac ggaaacctgc gccgtgggca cctctattgc cataaaacca ctgacccgtg
    19921 cacgcagatt tgccagtaac tgtgactggc gagcgaacgc ctgttgatgg caaaacagca
    19981 cctggcggtt actcacggca atcacgtcat tatgaaaaac gccctggtcg ataacgtccg
    20041 ggttttgctg ggcgaaaatc acctgttggg gattcacctg attcaacctt gccaccgcct
    20101 cgctggcttc acgggtctgc cgcgccggat aacgggaagg ccgggtatca ttgccctctt
    20161 ctcgcccgta gacaaaaagt tgcatacccg gttcaccgta atgaccgccg agacgattgt
    20221 ggtttgccgc cccctcatca ccgagcaagg ctacctgcgg caacgccgaa tggacgctaa
    20281 atttcttttc gtcgttaaaa atcgctttta acagcgattc ggtgacgggg gcttccagcg
    20341 aacggtgaaa tttattgttc aggttagcaa cagtgagatg cactttgcca tccagcgtat
    20401 cggcggatgg cgcgatcgtt gccgcattgg ctacccacat tggcgaagcg gaactgacgc
    20461 tggaaagcca gtgcggtgcc tggcgtgcaa ctttttccag tacctgctca tcgctaccac
    20521 tgaatcccaa ctgacgcagc accggaataa acggacgctc gtgcggcggg atcacggcct
    20581 gggggaatcc cgcatcggca agttttttca ttttcagtaa gccctgtttt gccgccagtc
    20641 gcgggttaga cacctgaaaa cggtgacggg tagaggcttc attaccaaac gacaggcccg
    20701 cgtaatggtg cgtcagccct accagcccgt cgaaattgac ttcccaggcg ttcatcgcac
    20761 cacctcatcg gaaaaatcca gcccggggtt aagcgttgcg ggcaacgtta acgagtccga
    20821 ctccagactt gccatcggcc aggcacaata atctgcggca taccaggcgc tggggcgatg
    20881 attgccggaa gcgccaatgc cgccgaatgg cgcggtactg gcagcaccgg taagcggttt
    20941 gttccagtta acaatccccg cccgtgcctc cagcaacagt tgatcgaatt tttcccgctc
    21001 gggggaaacc agaccgcaag agaggccgaa gcgagtgtta ttcgccattc gaatcgcttc
    21061 atcgaaattg tcataacgcc agacgcgcaa taacggccca aacacttctt catccggcac
    21121 gccagtaacg cctgtcattt caatgatccc cggcgtcagc aacgatgtcc ctgcttgtaa
    21181 taagcgcggc gcaagcaggg gccgtccgcc catcgcctcc agttcctgcc aggcagtaac
    21241 cacctgctgt gcggcctgct cagaaatcag cccgccaata aacggctgcg gttcgtcatc
    21301 ccaagtgccc ggcgttaacc gctggctgac ggcaaccagg cgagcaagaa atgcatcgcc
    21361 ctgcgttcca cttttcagca ataaacggcg ggcgcaggtg cagcgttgcc cggcagtgac
    21421 aaacgccgac tgaatggtca gatggacagc ggcatcgata tccgccacct catcgataat
    21481 tagcgggtta ttaccgccca tctcaagggc gagaattttc tccggctgac cggaaagctg
    21541 gcgatgcagc tggtagccgg tattggcgct gccggtaaac agcaaaccgt cgagatcctc
    21601 cagcgcactc agcgcctgac ccgtttcacg cccgccctgc accaggttca gcacgcccgg
    21661 cagcaagcca gcctgctgcc ataaacgcat taccgcttcg ccactccacg gtgtcagttc
    21721 gctgggttta aaaataatgg tgttacctgc cagcaatgcc ggaacaatat gtccgttcgg
    21781 cagatgacca gggaaattat acggtccaaa cactgccagt acgccgtgcg gacgatggcg
    21841 caagctcgcc gcgccgtccg gcatttcgct acgctgctca ccggtacgaa cgtgatacgc
    21901 cttaattgat atcgcgattt tattgatcat cgccgtcact tcggttgccg cttcccagcg
    21961 cggcttgccg gtttctctgg caataatcgc ggttaattca gctttattgc tttccagcaa
    22021 tccggcaaag cgttcaactc ttacctgacg atcgctaaat gagagcctcg cccagcgcgg
    22081 aaacgccgct cgggcagccc gacaagcctg ctcgacctga gcagcatcgg catcattgcc
    22141 ctgccataac acctcgcccg ataccggatt acgcttcaca cgcaatgcgc cctggcccgt
    22201 tacccagtca ccgttaatcc ataaagtcat gctgttttct cctctgcgca caggcgcacc
    22261 agacgaacgc gatcccctgc gtggcatttg agggcatcca gttgtgcggc ggttaaaatc
    22321 aaacgctcgg tcgctggatc ggtacgcacc agcaccacgc ggaaatggtg ataattttca
    22381 ttggcgacca ggcaggccgg aaaatcgccc tgcgcaggct gcccttcggc cacttccacc
    22441 agccgacttt tacggatggc gcgcacgcgg tcgatatcac actcaagtgt cggcccgccg
    22501 tcaaagatgt cgatatagtt acggtagcga aaaccttctt tctccagcac cgcacgggca
    22561 ggtgcggttt gcggatgtac ctgaccgatg acgtcctgtg cttcctggga taaaaagtgc
    22621 gtatagatcg gatgtttcgg catcagttct gcaataaatg ccttttgccc ggtgccgcag
    22681 agaaaatcag cgcggctaaa atccatcgaa aagaagcgtt taccgaggct ttgccagaac
    22741 ggtgaatagc cgtgttcgtc aatcaccccg cgcatttcgg cgaccacttt gtcattaaac
    22801 ttgtcgcgaa aagccgccat aaacataaag cgcgatttcg acagcaaata gccgttgccc
    22861 tctttgcgcc actccgggtc gagaaacagc gtgcacagct cgctgctgcc ggtgtgatcg
    22921 ttactgagaa acagcgtcgg caatgcgtta tagacattca gctctttcga agcgtgaacc
    22981 agcgtgccga cgcgatagtt gtaccaggga tcgttcagcc caaccgccac ctcaatggcg
    23041 caaatccccg ccacagtgcc tgactcgcta tcttccagta caaacacata accctgctca
    23101 cttttgggca gttcgccttg ccaggttttg attgcccttt caatacgcac cgaaagcgtg
    23161 gcttcattgg cgggaagcga cgtcaggccg ccgcccgttt tgctggcaag ctgcatcagc
    23221 gccgagacat ctgagcgctc aacgggacga atgaccatca tgatgaacct cggctaacaa
    23281 agtgttcgca agcagctgca aagcgctcca gtccggtcgt cacctcttct tcgctgacat
    23341 tgagcgctgg cgcaaaacgc accacgttgc cacccgcaat cagcaccatc acgcctgctt
    23401 tcgccgcttc ctgagagagc tgtttcgctt gcccggcgta atcggcattc agtacacagc
    23461 caatcaaaag acctaagccg cgaacttcac tgaacaaact gtagtggtga ttaatggaat
    23521 ttagacgctc aacaaaccag tcgtgacgct gtttaacccc gttaagcatc tctggcgtgt
    23581 tgatgagatc cagcactttg cctgccaccg ccgaggccag cggattgccg ccataggtgg
    23641 tgccgtgagt gccaacggtc atcacgctgg cgcactcttc ggttgccaac aacgcaccaa
    23701 ccgggaaacc gccgcccagc gctttggcgg tagttaacag atcaggcgtc acgccgtagt
    23761 gcatataggc atacagttcc ccggtgcgcc cgacaccggt ttgtacttca tcaaagataa
    23821 gcaacgcatt gtggcggtca cacaattcac gcagaccttg taaaaatgcg ttgctggctg
    23881 gcaccacacc gccttccccc tggatgggtt cgacaatcac cgcacaggtg gcgtcgtcaa
    23941 tcagcgcact ggcagagtta atatcgttat atgcagcatg acgaatatcc ggcggcagtg
    24001 gcgcaaaatc ctgtgaatag gctggctgcc cacccgcact gacagtaaac agcgtgcgac
    24061 catgaaacgc atttttgaac gccacgatgc cgctcttatg gctgccgtag cggtcgtgag
    24121 cgaatttacg cgccagtttt agcgccgctt cgttggcttc cgcaccggag ttacaaaaga
    24181 agacgcgatc ggcaaacgtg gcgtcgatca attttttcgc cagtcgcagt accggctcgt
    24241 tggtgtaacc gttgccggta tgccagaact tactcgcctg ttcgttcagc gcctcacgca
    24301 gttccggatg cgcatggccc agcgcgttca ccgcaatgcc acccgcgaag tcgatatact
    24361 ctttcccctg ctgctcccac aagcgcgaac cttcgccacg taccggtata aacggtgccg
    24421 gagcgtaaac aggtatcatc cattcatcaa agttttcacg cgtaattggc tgagacatag
    24481 cgacctctac agtaaataat tagttattta tatgttaata ataagtaatg tttgcgctgt
    24541 aaatgtagat tgcagggttc gtgccagcca gtgataaaag tgcataaacg gcggaggcta
    24601 actggaaatc aagcagttat aaccacatca tatgcattta aagtgcatat aaagtgaata
    24661 cgtttgcgat gtgggtgaat aaaaagaata aaaaacgcaa tgttatgcag aagtaaaata
    24721 taattctgga attgtgatca ttgacgaaat ttactggaaa ttactgcgcc attctgacgc
    24781 aacgcgcacc aaaagcgggc attttttgcg ccatcgttga catcattaac aaccatcgat
    24841 caaatcactt aacaacaggc ggtaagcaaa gcgaaattct gctaccatcc acgcactctt
    24901 tatctgaata aatggcagcg actatgaaat ttgtctcttt taatatcaac ggcctgcgcg
    24961 ccagacctca ccagcttgaa gccatcgtcg aaaagcacca accggatgtg attggcctgc
    25021 aggagacaaa agttcatgac gatatgtttc cgctcgaaga ggtggcgaag ctcggctaca
    25081 acgtgtttta tcacgggcag aaaggccatt atggcgtggc gctgctgacc aaagagacgc
    25141 cgatttccgt gcgtcgcggc tttcccggtg acgacgaaga ggcgcaacgg cggattatta
    25201 tggcggaaat cccctcgccg ctgggcaata tcaccgtgat caacggttac ttcccgcagg
    25261 gtgaaagccg cgaccatccg ataaaattcc cggcaaaggc gcagttttat cagaatctgc
    25321 aaaactacct ggaaaccgaa ctcaagcgtg aaaatccggt gctgattatg ggcgatatga
    25381 atatcagtcc tggcgacctg gatattggca ttggcgaaga gaaccgtaag cgctggctgc
    25441 gtaccggaaa atgttctttc cttccggagg aacgcgaatg gatggagagg ctgatgagct
    25501 gggggttggt cgataccttc cgccatgcga atccgcaaac agcagatcgt ttctcatggt
    25561 ttgattaccg ctcaaaaggt tttgacgata atcgcggtct gcgcatcgac ctgctgctcg
    25621 ccagccaacc gctggcagaa tgttgcgtag aaaccggcat cgactatgaa attcgcagca
    25681 tggaaaaacc gtccgatcac gcccccgtct gggcgacctt ccgccgctaa tttagctgat
    25741 ctcctggctc aaactgggtc aggagaatta accttgagaa aaatcaacaa actgtcagta
    25801 atgatttgtt gcccgccgtc ctttgttata ccgtcactgc gtttttagtt gtctgaccac
    25861 ttctctatta tcaagtttga tataggaaac tccacgatga acgctgagcg taaatttctt
    25921 tttgcctgtc ttatttttgc gctggtcatt tacgctatcc acgctttcgg tttattcgat
    25981 ctgctcaccg atttacccca cttacagaca ctcattcgcc agagcggatt gttcggctat
    26041 agcctctata ttctgttatt catcattgcc accctctttc tgttaccagg aagcatactg
    26101 gtgatcgcgg gaggaatagt ttttggcccg ctcttaggga cactactatc attaattgcc
    26161 gccacgctgg cctcctcgtg ctcattcctt ctggcgcgct ggctgggacg tgatttactg
    26221 ctgaaatacg ttggccatag ccataccttt caggccattg aaaaaggcat tgcgcgtaac
    26281 ggtattgatt ttcttattct gacccgctta atcccgttgt ttccttacaa tattcaaaat
    26341 tacgcttacg gattaaccac aatcgccttc tggccttata cccttatttc ggcactcacg
    26401 accctacccg gtattgttat ttataccgtg atggcaagcg atctcgccaa tgaaggcatt
    26461 acgctgcgct ttattttaca actctgtctg gcgggcctgg cactgtttat tctcgtccag
    26521 ctcgcaaaac tctacgcccg acacaaacat gtggatctgt ctgcttctcg ccgcagccca
    26581 ctttctcacc caaaaaatga aggatagaac gatgttgcaa cattattcag tgtcatggaa
    26641 aaaaggactg gctgcactct gcttactggc tgttgctggg cttagcggct gcgatcaaaa
    26701 agagaatgcg gctgcaaaag tggaatacga cggactttcg aacagccaac cactgcgtgt
    26761 cgatgccaat aaccatacgg taaccatgct ggtgcaaatt aatggtcgtt tcctcaccga
    26821 cgacactcgt cacggtattg tgtttaaaga tggctccaac ggacataaat cgctgtttat
    26881 gggttatgcg accccgaaag cattttatga agccctgaaa gaggcaggtg gtacgccggg
    26941 cgaaaacatg acaatggata ataaagaaac gactcatgtc acaggcagca aactggatat
    27001 ttcggtcaac tggcaagggg cggcaaaagc gtattccttc gatgaagtga ttgttgacag
    27061 taatggcaag aaactggaca tgcgctttgg cggtaattta acggcagcag aagagaagaa
    27121 aacgggttgc ctggtgtgtc tggatagctg cccggtcggc atcgtcagca atgcaacata
    27181 cacttatggt gcggtggaaa aacgcggcga agtgaaattc aaaggcaatg cctcagttct
    27241 cccggcggat aacacgctgg caacggttac ctttaaaatc accgaataaa gcaggataaa
    27301 ggatgatgaa gatgcaatcg cgtaaaatct ggtactaccg tataaccctc atcatcctgt
    27361 tgttcgctgt gctgctggca tgggcgctgc ttcccggcgt ccatgagttt atcaatcgca
    27421 gcgttgcggc gtttgccgcc gtggaccaac agggtataga acgctttatt cagtcttacg
    27481 gcgcactagc ggcagttgtc tcgttcttgt tgatgatttt acaggccatt gctgcaccgc
    27541 tacctgcgtt tttgatcacc tttgccaatg cgtcgctgtt tggcgcgttc tggggcggct
    27601 tactgtcgtg gaccagttcg atggccggcg cggcgctgtg cttttttatc gccagagtga
    27661 tgggccgcga agtggtggaa aaattaaccg gcaaaaccgt acttgacagt atggacggct
    27721 ttttcactcg ctacggcaaa cacaccatcc tggtatgtcg gttattgcct tttgtccctt
    27781 tcgatccaat cagctatgct gccggtttga cttcaatacg ttttcgctcg ttttttatcg
    27841 ccaccgggct tggtcaatta ccggcgacta ttgtttattc ctgggcgggc agcatgttaa
    27901 caggcggtac tttctggttt gtcaccggac tgtttattct gtttgccctg accgtggtga
    27961 tttttatggc gaagaaaata tggcttgagc gccagaagag gaatgcctga tgggtttacc
    28021 gccgcttagc aaaattcctt tcattttacg tccgcaggcg tggctgcatc gtcgccatta
    28081 cggcgaggtg ctaagcccga ttcgctggtg ggggcggatc ccgtttatct tttatctggt
    28141 gtcgatgttt gtcggctggc tggagcgcaa acgctcaccg ctcgatccgg tagtacgatc
    28201 gcttgtcagc gcgcgcattg cgcaaatgtg cctgtgtgag ttttgcgtgg atatcaccag
    28261 tatgaaagtc gccgagcgta ccggcagcac cgataaactg ctggcagtgg ctgactggcg
    28321 gcaaagcccg ctctttagcg atgaagaacg gctggcgctg gagtacgccg aagccgcaag
    28381 cgtaacgccg ccaacggtcg atgatgctct gcgcgcccga ctggctacgc attttgacgc
    28441 tcaggcgctc accgaactga cggcattgat aggcctgcaa aatctgtcag cccgttttaa
    28501 ttctgccatg gacattcccg ctcaggggct gtgccgtatt cctgaaaaac gttcttaagg
    28561 agagaagatg cgccattgtg ggtggttgct gggattgtta tcgctgtttt ctttggcaac
    28621 acatgccagt gactggcagg aaataaaaaa tgaggccaaa ggacaaaccg tctggtttaa
    28681 cgcctggggc ggcgataccg caattaaccg ctatctcgac tgggttagcg gcgagatgaa
    28741 aacccattac gctataaacc tgaagattgt tcgtctcgcg gatgccgcag acgcggtgaa
    28801 acgcattcag accgaagttg ctgccggacg taaaacgggc ggttcggtgg atctgctctg
    28861 ggtgaacggc gaaaacttcc gcaccttaaa agaggccaat ttattacaaa ccggctgggc
    28921 ggagactctg cccaactggc gctatgtcga cacacagctt ccggtgcggg aagatttttc
    28981 agtgcctaca gaaggggctg aatcgccctg gggcggcgca caactgacgt ttatcgcccg
    29041 ccgcgatgtt acgctacagc caccacaaac gccgcaagcc ttactggagt ttgctaaagc
    29101 caatcccggc acggttacct atccgcgccc accggacttt accggcacgg cgtttcttga
    29161 acagttgctg attatgctaa cgccagatcc cacagcatta aaagaagcgc cggacgatgc
    29221 cactttcgcc cgcgtcactg cgcccttgtg gcaatatctt gatgcactgc atccgtattt
    29281 gtggcgcgaa ggaaaggatt tcccgccttc gcccgcgcgg atggatgctc tgctgaaagc
    29341 taacacattg cgcctgtcgc tgacctttaa ccccgcgcat gcgcagcaaa aaatcgccag
    29401 cggcgatttg cctgcaagca gttacagttt tggttttcgc gaggggatga ttggcaacgt
    29461 ccatttcgtc accattcctg ccaacgcgaa tgccagtgct gcggcgaagg tagttgccaa
    29521 tttcctgctc tcacccgatg cgcaactgcg taaagcagat cctgctgtct ggggcgatcc
    29581 ttctgttctc gacccgcaaa aactgcctga cgggcagcgc gaaacattgc aatcgagaat
    29641 gccgcaggat ctgccgccgg tactggctga accgcacgca ggttgggtaa atgcgctgga
    29701 acaagaatgg ctacaccgtt acggtacgca ttaatctttt tgctgtgggc gatgatagcg
    29761 gtgatttatg caccgctgat cccggcagct ctcacgctga tatcgcctgc tttgtcgttg
    29821 acgcactggc aggcgttatt tgccgatcca cagttaccgc aggcattact ggcgacgctg
    29881 gtgtcgacaa ccattgcggc ggtcggggcg ttgttgattg ccctgctggt gattgtggcg
    29941 ttgtggccag ggccgaaatg gcagcgtatg tgcgcccgtc tgccgtggct gctcgccatt
    30001 ccccatgtgg cttttgccac cagcgccctt ctgctctttg ctgacggagg gctgctttat
    30061 gactatttcc cgtatttcac tccgccaatg gacaaattgg gtattgggct gggcctcacc
    30121 ctggcggtga aagaaagcgc atttctgctg tggatcttag cggcagtatt gagcgaaaaa
    30181 cggctgttgc agcaactcat tgtgctggat tcgctgggct acagccgctg gcaatgcctg
    30241 aactggctgc tgttgccctc cgtcgcgtct gcgttagcaa tggcgatgct ggcgattgtc
    30301 gcctggtcgc tgtcggtcgt ggatgtggcg attattcttg ggccaggtaa tcccccgacg
    30361 ctggcggtaa ttagctggca gtggttaact cagggcgacg ccgatcaaca aacgaaaggc
    30421 gcactcgcca gcctgctgct gatgctgtta ctcgccgcct acgttttgct gggctatctg
    30481 ctatggcgtg gctggcggcg tactattccc cgcgtagatg gcgttcgtaa gcctgccacg
    30541 cctttattgc caagcaatac gctggcgagt tttttaccct taaccggtgt gctgtgtgtg
    30601 gttctgctgg cgatcctcgc ggatcagtcg acgatcaata gtcaagcgct catcaacagc
    30661 ctgacaatgg ggctggtggc ggcattcatc gctttgctct tgttactgct gtggctggaa
    30721 tgggggccac agcgtcgcca gttgtggcta tggttgccca ttttattacc cgctctgccg
    30781 ctggtggcgg gccagtacac gctggcgcta tggctgaacc tggatggaag ctggacggcg
    30841 gtggtctggg ggcatctgct gtgggtaatg ccgtggatgc tgtttatcct gcaacccgcc
    30901 tggcagcgca ttgattcacg gttaattttg attgcgcaaa cactgggctg gtcgcgggcc
    30961 aaaatcttct tttacgtaaa atgcccactc atgttgcgcc ctgcgctgat tgccttcgcg
    31021 gtgggatttt cagtcagtat tgcgcagtat atgccgacgc tgtggctggg cgcggggcgt
    31081 tttccgacgc tcaccactga agcggtggca ttaagcagcg gcggcagcaa cggtattctc
    31141 gccgcccagg ctttatggca actgctgtta ccgcttatta tttttgccct gaccgcgtta
    31201 gtcgtaaaat gggtaggtta tgtcagacaa ggactccgct aatgctctgc gtgaaaaatg
    31261 tttcgctacg tttaccagaa agccgcttgc tgacaaacgt taactttaca gtagataaag
    31321 gtgacattgt cacgttaatg ggaccatccg gctgcgggaa atccactctg ttttcgtgga
    31381 tgattggtgc gctggccgga cagttttctt gtacagggga gctatggctt aatgagcaac
    31441 ggattgacat gctacccacc gcacagcgtc agattggcat tcttttccag gatgcactgt
    31501 tatttgacca gttcagcgtc gggcaaaatt tactgctggc gctaccggcg acacttaagg
    31561 ggaatgcccg acgtaatgcc gtgaatgatg cacttgagcg ttcaggcctt gacggagcgt
    31621 tccatcagga tcctgccact ttgtctggcg gtcagcgagc gcgcgttgct ctgcttcgcg
    31681 cccttctcgc tcagccaaaa gcgttgctac tggatgagcc attcagccgt cttgatgtgg
    31741 ccctgcgcga taattttcgc cattgggtgt tcagcgaaat tcgcgccatg gcgatccctg
    31801 ttgtgcaggt gacgcacgat cttcaggatg ttcctcctga tagccccgtt ctggatatgg
    31861 cgcagtggtc agaaaattac aacaaactgc gataacgcaa agtttttccc gatgcgtcag
    31921 ttcagaatgg cgctctcaaa actacaatgt cgggattttc gatgaaacgt gtttctcaaa
    31981 tgaccgcgct ggcaatggct ttagggctgg cttgcgcttc ttcgtgggcc gctgaactgg
    32041 cgaagcctct tacacttgac cagcttcaac aacaaaatgg caaagcgata gatactcgcc
    32101 ccagcgcgtt ttataacggc tggccacaaa ccttaaatgg cccttccggt catgaacctg
    32161 ccgccttaaa cctctctgct agctggctcg acaaaatgag caccgaacag ctcaacgagt
    32221 ggatcaagca acataacctg aaagccgatg ccccggtggc actgtacggt aatgacaaag
    32281 atgtcgacgc cgtcaaaacg cgactgcaaa aagcaggttt tacgcatatc tccatcctga
    32341 gtgacgcgct aagcgaacct tcccgtctgc aaaaactgcc gcactttgaa cagctggtat
    32401 atccgcagtg gctgcatgac ctgcaacaag gtaaagaggt tacggcgaaa cctgccggtg
    32461 actggaaagt cattgaagcg gcctggggcg ctccaaaatt ttaccttatc agccatattc
    32521 ccggcgctga ctacatcgac accaacgaag tggaaagcga accgctgtgg aacaaagttt
    32581 ctgatgaaca actgaaagcg atgctggcaa aacacggcat tcgccatgac accacggtca
    32641 ttctgtacgg gcgtgacgta tacgctgcag cgcgtgtggc gcaaattatg ctttatgccg
    32701 gcgtgaaaga tgtgcgcctg ctggacggag gctggcaaac ctggtccgac gcgggtctgc
    32761 ccgttgagcg cggtacgcca ccgaaagtga aagcggaacc ggatttcggc gtgaagatcc
    32821 cggcacaacc gcaactgatg cttgatatgg aacaagcgcg tggactgctg catcgccagg
    32881 atgcatcgct ggtgagcatt cgttcgtggc cagaatttat cggtacgacc agcggttaca
    32941 gctatattaa accaaaaggt gaaatagccg gagcacgttg gggacacgca ggtagcgact
    33001 cgacgcatat ggaagatttc cataacccgg atggcaccat gcgcagcgcc gatgatataa
    33061 ccgctatgtg gaaagcatgg aatatcaaac cagatcagca agtttcattc tactgcggca
    33121 ctggctggcg cgcgtcagaa acctttatgt acgcacgcgc aatgggctgg aataacgtct
    33181 ccgtttacga cggtggctgg tacgaatgga gcagcgatcc aaaaaatccg gtagcaaccg
    33241 gtgaacgcgg cccggacagc agtaaataac attgcaatta ctgacgctgg agcgacttca
    33301 gcgtcagata cccactccac acccgcgtaa aggtcgtcat ccagcacaac gcaccaaata
    33361 cccacgcaaa ccacggaaaa caggccggaa agaggcaact cagaacaaac agcaaaatcg
    33421 tctcgctgcc ttcggttaag ccgcccagat aataaaacga tttatgcgca taaccaggat
    33481 tatcaatctg atgtttcgcc gccagcgcag caaaagcgag aaaactgctg cccgtgccga
    33541 taaacgcaaa cagcagccag ccgcctgcca gggcgttttg ctccggtgcg gcgaggataa
    33601 acccaaaagg caccagcgcg taaaaaagaa aatcgagaga aatatcgaga aagccgcccg
    33661 cgtcggtaag ccctctgcgc cgcgccagcg caccgtccag accatcaagc agcctgttca
    33721 acaaaatggc gactagtgcc gccagatacc agcccagcgc cagaaaaggc agtgccagca
    33781 cgccgatggc aaatcccact aatgttaaac catctggcgt aatgcccggt ttatcaagaa
    33841 cccgcacgca ctgatgcaac aacggtttaa tccggggatg aagatggcgg tctagcacag
    33901 gcactcctta aatataaagc ctttctgatt gagcaacagt gcggatatta tggcattttt
    33961 cgcttatctg cccgtgtgta atttatgaaa atgattgaag ttgttgccgc catcatcgaa
    34021 cgtgatggca aaattttact cgcgcaacgc cctgcccaga gcgatcaggc gggattatgg
    34081 gagtttgccg gtggtaaaat cgagccggat gaaagccagc ggcaggcgct ggtgcgtgag
    34141 ttaaacgaag aactgggcat cgaagcaact gttggtgact atgttgccag ccatcagcga
    34201 gaagtttcgg ggcggattat ccatcttcat gcctggcacg tacccgactt ccacgggacg
    34261 ttacaggcac atgaacatca ggcgctggtc tggtgctcac ctgaagaggc gctgcgatat
    34321 ccgctggccc ctgctgacat tccattatta gaggcgttta tggcttcacg cgccgccaga
    34381 ccagcggatt agtgcttagg gttttgtcat cccgttggca ttgcagcagt attccttcgg
    34441 ctttaattac tgccccttca gaataatttt gatcctgata aacgcagcac tgagtacagg
    34501 gctgcgctga ctgcccgcct gaactgaaca cttctggcgg tacgtttacc tccacgtccg
    34561 gatgataatg cgggttagcc agtgtaatta atggaaatgc taatactacg gcgatcaatg
    34621 ctcgactcac agggaactcc ttaacgttat tgtctcttct acagataacg gtagccgggc
    34681 ggcaaaactt tagcgtctga gttatcgcat ttggttatga gattactctc gttattaatt
    34741 tgctttcctg ggtcattttt ttcttgctta ccgtcacatt cttgatggta tagtcgaaaa
    34801 ctgcaaaagc acatgacata aacaacataa gcataatcgt attaatatat aagggtttta
    34861 tatctatgga tcagacatat tctctggagt cattcctcaa ccatgtccaa aagcgcgacc
    34921 cgaatcaaac cgagttcgcg caagccgttc gtgaagtaat gaccacactc tggccttttc
    34981 ttgaacaaaa tcccaaatat cgtcagatgt cattactgga gcgtctggtt gaaccggagc
    35041 gcgtgatcca atttcgcgta gtatgggttg atgatcgcaa ccaggtgcag gtcaaccgtg
    35101 catggcgtgt gcaattcagc tccgccatcg gtccgtacaa aggcggtatg cgcttccacc
    35161 cttcagtaaa cctttccatt ctcaaattcc tcggcttcga gcaaaccttt aaaaatgccc
    35221 tgactactct gccgatgggt ggtggtaaag gcggcagcga ctttgatccg aaagggaaaa
    35281 gcgaaggcga agttatgcgt ttctgccagg cgctgatgac tgaactgtat cgccacctgg
    35341 gcgcggatac tgacgttccg gcaggtgata tcggcgttgg tggtcgtgaa gtcggcttta
    35401 tggcggggat gatgaaaaag ctctccaaca ataccgcctg cgtcttcacc ggtaagggcc
    35461 tttcatttgg cggcagtctt attcgcccgg aagctaccgg ctacggtctg gtttatttca
    35521 cagaagcaat gctaaaacgc cacggtatgg gttttgaagg gatgcgcgtt tccgtttctg
    35581 gctccggcaa cgtcgcccag tacgctatcg aaaaagcgat ggaatttggt gctcgagtga
    35641 tcactgcgtc agactccagc ggcactgtag ttgatgaaag cggattcacg aaagagaaac
    35701 tggcgcgcct tatcgaaatc aaagccagcc gcgatggtcg agtggcagat tacgccaaag
    35761 aatttggtct ggtctatctc gaaggccaac aaccgtggtc tgtaccggtt gatatcgccc
    35821 tgccttgcgc cacccagaac gaactggatg ttgacgccgc gcatcagctt atcgccaatg
    35881 gcgttaaagc cgtcgccgaa ggggcaaata tgccgaccac catcgaagcg actgaactgt
    35941 tccagcaggc aggcgtactg tttgcaccgg gtaaagcggc taatgctggc ggtgtagcaa
    36001 catcgggcct ggaaatggcg caaaacgctg cgcgcctggg ctggaaagcc gagaaagttg
    36061 acgcacgttt gcatcacatc atgctggata tccaccatgc ctgtgttgag catggtggtg
    36121 aaggtgagca aaccaactac gtgcagggcg cgaacattgc cggttttgtg aaggttgcgg
    36181 atgcgatgtt aagccagggc gtgatttaag acaattgtgc cggatacagc gcaaacgcct
    36241 tatccggcca taaaaatctt cagtatcaga tggttgaaag aacctttata ttatcactcc
    36301 attgcccgcc tcttctgatg gcgggctttt tttcggcgct ctcttgcgtg gcgaatcctt
    36361 tttcttccct tctccaccgc cgggagccat tattccccga aactgcctta ccgacgtgcg
    36421 ctttgcctga tcaatcaact ggtacaatgt ccccaccagc ggctgcataa agtcctgata
    36481 gcgacactgc ttttcgctga tttgcgtcag caccgattcc cagtgcgcgg tcatgtccgg
    36541 tcgcgtcgcc atttctggca gcgaatggaa tagcgctttt ccggcgtcgg tggagtggat
    36601 atagcgccct tttttggtca ggaaaccccg cttgaacaac agttcaataa tcccggcacg
    36661 cgttgcttct gtccccagac catcggtcgc acgaaggatc tttttcagat ctttgtcctg
    36721 cacaaagcgc gcgatcccgg tcatcgccga aagcagtgtt gcatcggtaa aatggcgcgg
    36781 cggctgggtt tgccgctcta ccacttcgcc tttttcgcac aacaattcat cgcctttcgc
    36841 caccacaggc agcggcgtgc cgtcgttttc ttcatcgcgc tctttgctgc ctaacagcgt
    36901 gcgccagcct gcttcagcaa gaaaacgggc tttagcgaca aatttgcctt tggcaatgtc
    36961 cagttcgata acacacttgc ggaacaccgc atccgggcag aactgcatca agtactgacg
    37021 ggcaatcagg ttatagacct tcgcttcgtt ctccgtcagg ttgatcgcag aactccgtgc
    37081 ggtcggaatg atggcgtggt gcgcatcgac ctttttgtca tcccaacagc ggttgcgtat
    37141 atctggatct accactggct gcggcaacag atccggtgca tgaacgctga tagcattcat
    37201 caccgcgtgg cgtccggcaa aatgttcttc tggcaaatag cggcaatcgg aacgcggata
    37261 agtgattagc ttgtacgttt cgtacagctt ctggcagata tcaagcacgt tctgcgcgct
    37321 cagaccaaaa cgtttagccg cttcaatctg caacgccgaa agcgaaaaag gcagcggcgc
    37381 ggattctgat tcccgtttat cgttatagct ggtgacaata gctggttgac cactaatacg
    37441 gttaaccaca tgctccgcca gtggacgatg taacaagcgc ccttcttcat cctggtacgg
    37501 ttcacacgct tcgctcggtt gccagatagc ggtaaaccgc tcatcggcag gtgtcacgat
    37561 atgtgctttg acttcaaaga agtctttcgc cacgaagttt tcaatctctt cgtcgcggcg
    37621 caccaccagt ccgagtacgg gcgtctgcac gcgtcccacg gaaagcacac cctgataacc
    37681 ggcattgcgg ccgagaatgg tatacgcacg ggtcatatta atgccgtaca gccagtcagc
    37741 ccgcgcccgc gccagtgcag aaacgcacag cggtacaaac tcgctattgg agcgaagacg
    37801 atcgatcgcc cgctcaaccg cctgcgggtt caagtcgttt atcaaacaac gctgtacctg
    37861 ctggcgcttt tccggtgcca gttgcaggta gtccagcact tcatccacca gcagttgccc
    37921 ttcgcgatcc gggtctccgg cgtgaacgat ttcgctggct tcatgcagga agcgtttgat
    37981 gacattaagt tgtttagtca cggagggtcg gggctgtaat tgccactttt ccgggacaat
    38041 tggcaaatcc gcaagattcc agcgcgcata gcggctgtcg taggcgtctg gctgcgcctg
    38101 ctcaagcagg tgaccgatac accaggtcac cacctgacca ttaccgcact cgataaagcc
    38161 atcgcctttc cggtgcggtt taggcaggac atcagcaatg gcgcgcgcca gactcggttt
    38221 ttcggcaata aacaaccgca ttgaattaac ggatctcaac catggcacga ccgccgcgcg
    38281 ctggcaccag ttcgccaatc gccgtcagtt caatgccaaa ctcggcggct gtagctttga
    38341 cctcattttc tgcttccggc atgaccgcca gcagcaaacc gccagaagtt tgcggatcgc
    38401 acagcagatc gcgcacttca cgcggcattt cacccatcag atgaccgtag ctggcaaagt
    38461 tacgttcggt gccgccaggc actgcgccca acttaatgta ctcttcaacc cccggcaatt
    38521 tcgggatcgc gtcatagtcg acgcgcgcct gcacacctgc gccctgacac atttcgctta
    38581 aatgccccag taaaccaaaa cccgtaacgt cggtcatcgc ttttacgcct tcgatgttgg
    38641 caaaggacac gcctgcgatg ttcatccggc acatcacttc cgtcgccagt ccctgatgtt
    38701 ctggtttcag cagtgatttt ttctcagccg tggtaagaac gccaatcccc agcggtttcg
    38761 tcaggaacag tttgcatccg gcttgtgcgg tactgttttt cttcacccgc tcggtcggta
    38821 cgatccccgt taccgccaga ccaaaaatcg gctccggcgc atcgatggag tgaccgccag
    38881 ccagcgcaat acccgcctga cggcatgcat agcgtccacc ttcggtcact tcgcgggcaa
    38941 tttccgggga aagtttgtta atcggccagc cgaggatcgc aatcgccata atcggtttgc
    39001 cgcccatagc aaagatatcg ctgatggcgt tagtcgccgc aatgcggcca aaatcgaaag
    39061 gattatcaac gatcggcata aagaagtcgg tggtactgat aacgctggtg ccattgccca
    39121 gatcgtacac cgccgcatcg tcgcgggttt cattacccac aagcaaattc ggatcaacaa
    39181 acttcgcctg ctcactgtgc aggatggttt ccaacacttt tggggaaatt ttacagccgc
    39241 aaccagcgcc gtggctgtat tgggtcaaac gaatcgagtt ctcgctcatg gacatctcct
    39301 gtcaatgcaa tccgggtatg gtaaccctca ttccatgaag tgataagtga gagtgtctga
    39361 attcctgcgc ctttgctcac aatccagaca gtttcgcgac aattatcaga aataagtcac
    39421 aaacggcgtc gggtccggga cgtttatcga cgtagatgct ttcaactgcg gcgtaccgag
    39481 gtagagaaaa ccgacaattt tatcctgctc acggcaaccg aatgcttcac gcactaccgg
    39541 actttcagtt aatgcaccac tgcgccagat gccgccaaac ccctgggcaa ctgctgccat
    39601 ttgcatcgcc atgaccgcgc atcccgcaga catttcctgt tcccagcgcg ggactttatg
    39661 attttcttca catttcgcca ccaccgttat gatgagcggt gcgcggaacg gcgcattacg
    39721 cgctttgtcg attgctttgt tatcactacc ggcagcaatc gccccctgct ccagtacggc
    39781 gctgaaacgc tcgcgccctt ccccttcaat cacaaagaaa tgccacggtt gcatggactt
    39841 atggtccggc gcacgcatac ccgcacgcag gatgttttgc agttgttcac ccgttggcgc
    39901 gggttcagcc aggcgggagg cgctacggcg attgatcaat agttcgagtg catccatttg
    39961 attaactcct gtcatgatat ttattcacaa aattaacacg agagtggatt ttgttacagc
    40021 ccagtccgca attcctgctg acaagtgccg gttgggtcat tacgataacc acatctattg
    40081 cgcctgaaac aggtgtgacc ttaagttggg agaatacatg cgaacccttt ggcgatttat
    40141 tgccggattt tttaaatgga cgtggcgtct gctgaatttc gtccgtgaaa tggtacttaa
    40201 cctgttcttt atttttctcg tgctggttgg tgtggggatc tggatgcagg tcagtggtgg
    40261 tgattcgaaa gaaacggcca gtcgtggcgc actgctgctg gacatttctg gtgtgatcgt
    40321 cgataaaccc gacagttctc agcggtttag taaattaagc cgccagctgc ttggtgccag
    40381 ttccgatcgt cttcaggaaa actcactgtt tgatatcgtc aacaccattc gccaggcgaa
    40441 ggacgaccgc aatatcaccg gtattgtgat gaatctgaaa aacttcgcag gcggcgacca
    40501 gccgtctatg cagtacatcg gcaaagctct gaaagagttt cgtgacagcg ggaaaccggt
    40561 ttatgccgtt ggcgagaact acagccaggg gcaatattat ctcgccagtt tcgccaataa
    40621 aatttggctg tctccgcaag gcgtggttga tctgcacggc tttgccacca acggtctgta
    40681 ctacaaatcg ttactggata agctgaaagt ttccacccat gtgttccgcg tgggtacgta
    40741 taaatctgcc gttgaaccgt ttattcgtga tgatatgtcg ccggcagccc gcgaagctga
    40801 cagccgctgg attggtgagc tgtggcaaaa ctatctgaat actgttgccg ctaaccgcca
    40861 gatccctgct cagcaggtat tccctggcgc gcaagggttg cttgagggtt taaccaaaac
    40921 cggtggcgat accgcgaaat atgcgctgga aaacaagctg gtcgatgcac tggcatcgag
    40981 tgccgaaatc gaaaaaactc tgaccaaaga gttcggctgg agtaaaactg ataaaaatta
    41041 tcgcgccatc agttattacg attacgcatt gaaaacgccg gcagataccg gtgacagtat
    41101 cggtgtcgtc ttcgctaatg gcgcaattat ggatggcgag gaaactcagg ggaatgttgg
    41161 cggtgatacc actgcggcac aaatccgcga cgctcgcctt gacccgaaag tgaaagcgat
    41221 tgttctgcgt gttaatagtc ccggcggcag cgttaccgcg tctgaagtga ttcgcgctga
    41281 actggcagca gcccgggcag cgggtaagcc tgtggttgta tcgatgggtg gcatggcggc
    41341 atctggtggt tactggattt ccacaccagc taattacatt gtggctaacc ccagcaccct
    41401 gaccggttct atcggtatct tcggcgtgat caccaccgta gaaaatagtc tggattcgat
    41461 tggtgttcat actgatggtg tctcaacttc accgctggcg gatgtttcta tcaccagggc
    41521 actgccgccg gaagtgcagc agatgatgca gttaagcatt gagaatggct ataaacgctt
    41581 tatcacgctg gttgctgatg cgcgtcattc aacgccggag cagattgata aaatcgccca
    41641 gggccacgtc tggaccggtc aggatgcaaa agctaacggg ctggtcgata gtctcgggga
    41701 tttcgatgat gcggtcgcca aagcagcaga gctggcaaaa gtgaaacagt ggcatctgga
    41761 atactacgtt gatgaaccga ccttcttcga caaagtgatg gacaacatgt ctggttctgt
    41821 ccgggcaatg ttgccagatg cgttccaggc catgttacct gcaccgctgg cctcggtagc
    41881 ctctaccgtt aaaagtgaaa gcgacaagct ggccgcgttt aacgacccac aaaaccgtta
    41941 tgcgttttgc ctgacctgcg ccaacgtgcg ttaagtcctg caaaaatgtg gccgatatgc
    42001 tgtcggccac actcctgaat cggactgtct ttcactccct ctctccacta cattcccttg
    42061 ctcatttagc atctgatatg gagtcatcag tgaataaggc cccctcttta attgccgcta
    42121 tcgtcctcgg actggggatt agcgcctgtg gttattttgt tggcgatggt gttaaacatt
    42181 taaaaaccaa taaccgttat gtaaatgtgc gtgggctttc tgaaaaagaa gttcgcgcag
    42241 atacggcaga attaacaatt gcgattaact ttaagggtaa tattcccggc gaactgttcc
    42301 cgaaactgga agacgcgcag aaaaaaattg ttgccgaact caatgctcag gggattaacg
    42361 agaaagagat aaccctgggc caatggacaa gcaagcgaac agattccttt tatctgaaag
    42421 atgatcccac aatgccacgc tataacgcag acgggtcagt gacgataaaa acccataatg
    42481 ttgctgctgt cgaaaaagtc gtcgcgaaat taaacgaact gcaagtcgct acggagggcg
    42541 ctatcgctga gagcaaagtc gcctatcgct ttaatggtat tggcgcactg cgcgctgaga
    42601 tgattgccgc cgccaccaaa gatgcacgca acgcagcatt acaatttgca acggactcag
    42661 gtagccaggt ggggtcaatt agcgatgcct cacaaggcgt gttccagatc ttcgccagtg
    42721 gcagtgatga agatgatcct acggcgatta ataaaacggt acgcgtagtc accaccgtaa
    42781 cctatgcgtt gcaggattaa ccacttttct ccggcgggac actaatccct ccgttctgcc
    42841 ggacttttct catatccaca gagtatccag gtgcgctcgc tgcccctcac gtatatactt
    42901 ttgctctttc gatatcattc atatcaatat catgcaaaag aaatcaattt acgtcgccta
    42961 cacgggcggg accatcggga tgcagcgttc cgagcagggt tatattccgg tgtcaggtca
    43021 tctacagcgc caactggcgc tgatgccgga attccatcgc ccggagatgc cagatttcac
    43081 cattcatgaa tatacgccat tgatggattc ttctgatatg acgccagaag actggcagca
    43141 tattgctgaa gatattaaag cgcactatga cgactatgat ggttttgtca ttctgcacgg
    43201 cacagacacg atggcgtata ccgcctctgc actgtcgttc atgctcgaga atctcagtaa
    43261 accggtcatt gtgacagggt cacaaatccc gctggctgag ttacgctctg acggacaaat
    43321 taatctgctg aatgcgttgt acgttgcggc gaattatcct atcaacgaag taactctctt
    43381 ttttaataat cgactgtatc gtggcaaccg aaccaccaaa gcccatgccg atggttttga
    43441 tgcgtttgcc tctccaaacc ttcctccgtt actggaagca ggtatccata ttcgtcgttt
    43501 gaatacgcca cccgccccgc acggcgaagg ggaattgatc gttcatccaa tcacgccgca
    43561 accaattggc gtagtgacga tttatccggg gatttctgct gacgtcgtgc gcaattttct
    43621 gcgccaacct gtgaaagcat tgattctgcg ctcatatggc gtgggtaatg cgccacaaaa
    43681 caaagccttc ctgcaggaat tacaagaagc cagcgatcgc ggtattgtgg tggtcaacct
    43741 gacacaatgt atgtccggta aagtgaacat gggtggttat gccaccggta acgccctcgc
    43801 ccatgccggc gttattggcg gtgcagatat gactgtagaa gccacgctaa ccaaactgca
    43861 ttacctgctt agccagaaac ttgatactga aaccattcgc aaggccatga gccaaaacct
    43921 gcgtggcgaa ctgacgccgg atgattaagg agactgcaat gccccctcgc gccctgttac
    43981 tggtcgattt acaaaatgat ttctgtgctg gtggcgcgct cgccgtgccg gaaggtgaca
    44041 gtacggtgga tgtcgctaac cgcctgattg actggtgcca gtcgcgcggt gaagcagtta
    44101 tcgccagtca ggactggcat ccggcgaatc acggcagttt tgccagtcag cacggtgtag
    44161 agccttatac gccaggccaa ctcgacggtt tgccacaaac cttctggccc gatcactgtg
    44221 tgcagaacag tgaaggcgca caattacatc cgttactgaa gcaaaaagcg atcgcagcgg
    44281 tgttccataa aggcgaaaat cctttagttg acagttacag tgcctttttt gataacggtc
    44341 gtcggcagaa aactgcgctc gatgactggt tgcgcgctca tgtaatcaat gaattgatcg
    44401 ttatgggtct ggctactgac tattgcgtta agtttaccgt gctggacgct ttacagttag
    44461 gctataaggt gaacgtgatt accgatggtt gtcgtggcgt aaatatccag ccacaggaca
    44521 gtgcgcacgc gtttatggaa atgtcagcag ctggggcaac gctatatacg ctggcagact
    44581 gggaagaaac gcaggagtaa ttttacgctg gcctacaatt ctgtactggc attgtaggcc
    44641 agataaaaca catcagtgat acatctggta attgacgcca tcaacgaaag atttaattca
    44701 cctcagaaat ctcttccagc gacaccttcc gcgtttcgat gccaaaaatg gagagaacca
    44761 gcgcacagag cactaacatg acaccaagca ccataaacac cgtgatcgac ccataatgtg
    44821 ttaataatgc cgcaacgcca tagggcgtga agactgcgac gatccgtcct acggcattaa
    44881 cgaaacccga accacgcagg cgtaaatgcg ttggccaaag ttccgggata taaaccgccg
    44941 acgcgaagca aacatacatg tataaaaaga agatcatcac caggccatag attaaaatcg
    45001 cccactctgt tgtctgaatt gaatagatat agcctaacac ggcaataata ataagtaagg
    45061 cggaaccaaa taatcgacga gggaaatgat caataattaa tgccgcaata aatatcccta
    45121 ccggagcgcc aatcataata acagcggtca ttaatattga tttatcgaca tcaatgccgg
    45181 agttaacaaa tatggtcggc atccatacgg tgatggtata aagcgaaatg ttcattgcaa
    45241 ttaaaacagt aatcgcgact aatgtacgtc gtaacatttc ccctttaaac aggagccaga
    45301 aggtaccctt gattacctta accttgctgt tgctctggtt caaagtaagc gggggtaaac
    45361 gaatactctt ctctctttca atttgctgct ctacttcacg aagttggctt tctgcacctg
    45421 cgattcgccc tttccctgcc aaccatcgtg gcgactcaat aaagtattta cctgagagaa
    45481 accaggctaa cagtatgcca ataccgccca gcagaaacat tatccgccaa ctaaaaaaag
    45541 cgataaccac cacgcctatc gccgcagaca gcatgggcga ccagtttcca acaaatgaga
    45601 gccgcgcgga ccattttcca cgcaccgtcg cggggataaa ctccgtaaat gaggcatagc
    45661 caaccataat cagcgccccc attcctgttc ccatcaggaa gcgaaagaag atgagccagt
    45721 acatatcagg gacaaaagcg gcccctgttg ccgcaatacc gacgatgaga agatttatgc
    45781 gaaacgccct gcgccgccca aagtagtcac caataaaccc accggtaaga gagccgatga
    45841 aataaccaaa cattaatgcc gaggtaaagg cggcattgag gaaattattt gaccatccat
    45901 tgcttaccag ctttgctaag acgacattac cggagtaact caaaaacccc gttaataaca
    45961 gactaaagct tattatacca aatatacgat aatgaaaccg ggccaaaggc aagcggtcca
    46021 gtcttgcgcc aatttgatca tattgttcca ttgggtgcct cggatttgct aaaaaaggta
    46081 gcaattgcgg caaattcact tgccgcatct ttatcatcat tttatttcca ggcgcaggaa
    46141 caaataatat tgacaatgtg tgcttaaatt accacaccag ctggatatta ttgtctttgc
    46201 aaaatgctat ccactctgca cccggtgatt tatcagttat tatgtaatta atatgactaa
    46261 agtcagctaa ctggacaaaa gctttgcgat caaacttaga gtgatcaacc aataacgcaa
    46321 cttctgtcgc ctgacggatc attgtctttt tgatttcagc ttccgcttca ttagagtcca
    46381 gcgcgccgct gttaatatca agacctttac aactcattac catgatatcg acatggtagc
    46441 ggctgatgat ctctttagta attcttcctt gcagtgaaag tgtatttttg tttagttccc
    46501 cacccgttga aacgacttta atttctgact gagccagaac atgaatcgct tccgccgagt
    46561 tggttagcaa cgtcaggtca ctacggtcct gtaacaattt gagcaattcc attacggtac
    46621 tactggaatc ggctgccatg gtggttttat tgtcgacaaa gggtagtgcc ttgcgtgcaa
    46681 taagctgctt ctcttcataa aacgatgaag cgcgcttata aaaatggata ttctccgtca
    46741 acatcgctgt atttaaaaca gcaccaccat aggttctggt caaaaagcct tcatcttcca
    46801 acttctcaag atcgcggcga atggtttctt cggttacctg aaaaatccca ctcaaatttg
    46861 agactgtcac ctttttatcg ttggcaacca tttgcttaat tgcctgaatc ctgtcttttg
    46921 ccgccacgat tacacccctg tatcttttta catcacatta gcgcaattat cgcataaccg
    46981 atgtttactt tcaaaataac ctgtttgaat cacagatttt catcacagtt ttcacagaaa
    47041 cagaggtgaa tcgtgttgag tatttaacgc tccagggcct ctgccatttc cctcatcaat
    47101 gttgcgtctg catccgataa gttgatattc agtgccgcga cattttcacg tacctgttcc
    47161 ggcgcagtag ccccactaag aatggagatt aaatcactct gttttaatat ccacgccagt
    47221 gccagagtgg gaattgtgca ctgataacga gcacagagtg gctgccactg ttcaagcata
    47281 tcaatcactt tcagcatgtt ttcacgctgg aaccagactt tatttgcccg agcgccgccc
    47341 ggaacgtaat cacgcgtgat ggtgccggtc aacaatccct gctctagcgg ggaataaacc
    47401 tgaaccacaa tgccattatc acgacatagc ggcagcagtt cgttttccat cgcccggtcg
    47461 agaatactgt atttcgcctg aataatatcc agttcaccat gttgcagata ctcgcggata
    47521 tggtcagcat cgacgttagc agcgcctata gcgcgaattt tcccttcggc ctttaacgca
    47581 ttaagcactg caacagtttc agctatcggc gtaaaaaatg gcggcaccga ctgccagtgc
    47641 gtcatgtaga tatcgatgta atcaataccc agacgttgca agctggcttc tacctcttcg
    47701 cggatagatt ccggagaaag gtttttatac aactgccgat cgccaacttt gttgaataaa
    47761 cttccttttc gttcccagac aatgccgcat ttggtttcta ctacaacctg ttcacggggc
    47821 agttttttta acgcctgacc aacgataact tcactattgc caaagttata tcctggcgca
    47881 gtatcaatca ggttaatgcc gcaacgatgg gcttcaagaa tcgtatcaat gcatatttgt
    47941 cgatcgagat cgccattcca tgcaggaccg ccgccaatag cccatgtacc caaccccatt
    48001 cgcgaaagcg ttatatccgc tgtgcctaaa ggtatctttt tcatttgcct tcattatcct
    48061 tcgtattctt ccagcaattg ttcgaccagc tttctgtttt ttacaccggt ggtggcgccg
    48121 atgcttagaa ccgagatagc cgccgttgca ttggcaaagc gtgcgcattc tcgcagattt
    48181 ttgccttcta acagtgctgc aataaaacct gaagcaaagt tatcgcccgc accaatggtg
    48241 tcgatagcgg ttattcctgc gaccgccggc accttcatcg tcatgtcacc acgcttgata
    48301 aagcagccgt ctttacccgt tttaatcacc accgttttta cgccgcacgc aagaaagcag
    48361 tcagcaattt catccagtgt ctctttcccg gtgagtaatt ttgcctcggc aaaattagga
    48421 aacagataat cgacataact caatgcttcg caaatatcat tcagcgtttc attcaaccgc
    48481 ggtttgatca tatcggcaca gataatcatc tgccgggttt tagcttgcgt aaaaatttct
    48541 gttagcgctc gaccatccaa tagaggactg ttgaaaatac tggccagtga taataatttc
    48601 gcctgagaaa accgcgcaaa atcaacatcg tcaatattca atttccacag actgccgtta
    48661 cggtttgtga caaaggtccg ctcgccatcc tccgtcacca gtccaacgtt aatagaggta
    48721 tctatgctga cgtcctgctt caggctttga atatcaatat tctctttgcg gcaatggtcg
    48781 agaataaatt gccctgcggc atctttacca atacgactca ttaatgctgt gcgatggccc
    48841 agacgagaaa taattgttgc ttcatttatt gcatcacccc cggtggtcat tgcgattctt
    48901 tcaagaggat aagaatccac atcaaagata tttttactga ccggttgcaa tggaatatca
    48961 acaatagcgg cacctataca aataacgtcg agattatcca tattattatt ccgctttgcc
    49021 atcagaaccg aacagtttaa ttttatccaa tgcccgttct tttatagctt tacgcacttc
    49081 acgttctaaa tgcaggaaag gctgatcctg gttttctttc actgctacca ttgcggcctg
    49141 acagagctcc gtatgaatgt tgattttcgc aatacccaac gaaattgcag ttttaatgtc
    49201 ggcatcactg atccctgatg cgccatgcaa aaccagcgga acagaaacag catcgcgtac
    49261 gcgtttgacg acctcaaagt tcaattgtgg ctctgacgta taaaccccat gctggttgcc
    49321 gatggcgaca gccaatgagt cacagcccgt acgttcaaca aattcagccg cctggtcagg
    49381 atcggtatag tgatagcctg ccagcgcttc ctcataaacg gtttcattac cgacatgccc
    49441 taattccgcc tctaccggaa tacccagcgg atggaagaaa tcaacagcct ctttggttaa
    49501 acgaatattt tcttcgaaat caaatgcaga agcatcacgc attaatgaat tcataccatg
    49561 agtccaggcg ttatgaataa tctccatact ccgaccatga tcccaatgag ttattaccgg
    49621 caccgttgct ttttgtgcca ttgataccat catgtgagag aaatcttcaa atgaggtgtt
    49681 gccgacaaaa cctgtgccaa aagaaataat aaccggtgat ttcgcttctt cggctgcgtc
    49741 gataacgccc atcaacattt ctgcattcca tacgttaaaa tgggcaattg cataatgttt
    49801 atttgtggca tcgttttccc aatatctgat atctgcgagc atgttctgtt ctcccgtatt
    49861 aattaatcgc taattttaat aacgccttta ataatgtcgc gtttgttgtt aactgactct
    49921 tcaaatgcct gttgtacatc ccgataatcg taaatatgcg tcaccatcga tttcacatcg
    49981 aatcgccctg aagaaatagc ttcaatcgtg accggataac gattggcata gcggaatacc
    50041 gtctggatag tgacttcgcg attgattttg aggaaattga ttgccgaatc gccgggtaca
    50101 gtaccaacaa tcataatttt accgccgcgc atgaccagat aaggtgcctg tttaacggtg
    50161 accgcagaac ccgctgtttc aaaaacaata tctgcgccca tgtcttcggt aaattgctga
    50221 cagcgtgcaa tagtgtcttc ttttgcgccg ttaataacca ctgtcgcgcc gagctgttcc
    50281 gccattgtca gacgtttttc cagcacatca acgacggcaa tttccgttgc tcccaggcat
    50341 ttgcacgctt gcaacgtcat caaaccaata caacccgctc ccagaataat tatcttctta
    50401 cccggtttaa catctgccag catcgcggca tgcatcccga ctgcggcagg ctccaccagc
    50461 gccccttcca tcgtgtccat attgtctggc agtttgtaag taaagctctc cggatgacac
    50521 agatagtgcg ttaatgcgcc gcggtagttg ggttgtgtcg ccataaaatc aacgtccggg
    50581 cagatgttat atttgccttc cagacagtaa cgacagtgac cgcaaggaac gccaggttcg
    50641 atatttaccc gatcccccgg tttaaatttg cgcacgcggc ttcccacagc cacaaccgtc
    50701 ccggcgcatt catgacccag gccaatttct tgatttgggt ctttaggagg aataaacggg
    50761 cctgattcaa aaccatgtac atctgaacca caaataccga catattccac tttaatcaaa
    50821 acttcatctt ctttaggtac aggtatttct gctgaaataa ttttcattgt gcccggcacc
    50881 tgcaacattg cttttgaatt tttcattttg aatccaccag tattatttat tggctactgc
    50941 atcaatactt aaactttcaa cggagacacc tttggtttca attccaatgg tggcgatagc
    51001 aattgcgaca ataattgaaa cagcccccag aagaataaag actcccgtta cgccataact
    51061 actgagcagc actgcaacgg cataaggtgc ggcaatacca ctgattcgcc ctaccgcatt
    51121 cgccagaccg gagccacgga gtttggcctc tgtcggccag atctcaggga catacactgc
    51181 cgaggcatag caaacgtaca tatagacgaa agtaatcagg aagaaaccaa tcagcgttat
    51241 gagcaacata ctggtttgca gtgaatagat atatccgagc accgcaatca ggattaatag
    51301 ccccacaccc attgttttac gcggaatttt atccatcacc agcatggcaa taaaaatacc
    51361 aaatggcgcg ccaaacatac tcatggtatt taaaacaatc gagtctttta aattaattcc
    51421 ctgggtcatg aatatcgttg gcaaccagtt aattagtgtg tactgcacaa cgttcatggc
    51481 aatcagcaca caagagccta atatcacgcg tttcagtaat actcctgtca gtaaggctga
    51541 atacggcacc gcttgtggtg ctttaccgtc atcagcaata accacaggcg gcaaaggttt
    51601 acccgtctgg cgtatgacgc cttcttctat actccgcatg actttctcgg cttcctgata
    51661 acgtccgcgc gattccagcc agcgcgggga ttcaggaaag tagcgccagg ccagcgccgt
    51721 agcgataagt gacaatattg cagggataag cagttgtacc cgccagttcc actctgcact
    51781 aatcagcggc gtgagtccca tcgcaatcaa tgaacagagc ggatatgacc agttaccaat
    51841 aaaggaaacc cgactggacc acgttccgcg atttcttccg ggcatatatt cggtgaaacc
    51901 agcaaacagt gtaaccagta aagctcccag cccaacgccc atcacaaaac ggcaggcaat
    51961 aaggaaatcc atattcggtg agaaagcacc gacaaccatc gaggcaatat gaatggcctc
    52021 atagaggata aacgcatttc tgcgaccggt tttgtcaccg atgatgccgc ccaccagcgc
    52081 accgagaaac attccggcgg tcgtgattgc tgagaatgtg gcagtggtgg aattatctgt
    52141 ccagcccaac gctttcagct gcgcgaggat caagccacca acggcattac tccagcagac
    52201 aagcaggcca aacgcgacga tggcaaacat cgacgaatgc cagcggcaat ccggtaagcg
    52261 atccagccgt gcaccacaat gcggttttgt tatctgttcc atgcgataac gttccttcag
    52321 gagagtagtt attcatcaaa gtcgtaagtc atgatcactt tgattgcagt tttatcgacc
    52381 atcgcatcaa acccttcgcg ccattgcgac aggccgatac gatgcgtgat catcggtttg
    52441 actttgatag cgccgctggc taatagcctg atagcgttac gccatgaagt ggagtcatag
    52501 gccatatgcc caatgatgct tttgttccag gcggtaatgt cattaatcga gaaatcaaga
    52561 ggtttgaagc ccattccaac gcgtactact tccccattcg ggcggagcat ttcgatggct
    52621 tgtttcaatg cgatattggc accggagcat tcaatcacca gccccagatt gtctttgcca
    52681 caaatttgct ggcagcgtgc caccacatct tcggtagaac catttactac tgccgtcgca
    52741 cccagttctt ttgcaaccgg gaagcggacc gttacatctt cttgcagacc aacgacgacg
    52801 atatttaccg cccccataat ccgcgccatt tgtacggaga acagcccgag tgggccagtg
    52861 ccgatgacga ccacatcctg acctggaagg aatttcgatt gctgcgcgat ggatttatag
    52921 gcattacaga tagggtcaag tacggctgcg tcctcataat caacaccatc agggatttcc
    52981 cacaacgcat gacgatgaat tttgagaatt tcaccaggaa caagacaata tttggaaaaa
    53041 ccaccgcccc aggtattgtt atccagacca aggtttactt tttctgtaca acacagaaaa
    53101 tcaccttgtt cacaggccgg gcaaacgccg caaacgtgac cgctgttatc cgacacgacg
    53161 cgttgcccca ctttccagtc tttgactttt tcaccaacct gcgcaataca acctgcgaac
    53221 tcatggccgc ggatagagtt aaactcatcc gaaccgctat cgacattgta gtgcttcatg
    53281 tctgcgccgc agattgccgc ggctttaatt tcaatcacga catcttccgg gccacaaatg
    53341 ggttgtggga catcaatcat cttgtagcca ccaaaagcct tgccaaaccg agccagtgct
    53401 ttcattgcgt catcctctgt gttttgtttt gcttagatgg tcatcatact tacccacatg
    53461 atttttgagg tcaacattaa atctgtaaaa cacagataat gatctgcgtt ttacaactta
    53521 gatcacaatt acgcagaaaa tggctggggt tgttacaggt tgatggaagg cgggacgcaa
    53581 aaagagcaaa ttcgagaggg attcccggcc aaataggcct gagacttaag ttcaggagaa
    53641 gtcattcagg tgtgaacgcg actgcaagag atcggactgg gacttagcca ggtcggggcg
    53701 agataattga gatgagtcgt ggggtcattg ttggctatcc cctttataac cgcggcaaaa
    53761 aggggataaa ccacttactt aaacatggca ataggctttg ctgagatacc aaaatcttct
    53821 tttaactgct gtttgctctt catgaccatc tgaccatttg tgtcaattgt catatgctgt
    53881 gcttcggtat tatggcgggc ttgccacagc atcaccagtt gcaggcagtt ctctttttgt
    53941 tcctcggtca acgtaacgcc atcaggccat ttccccagtt caacggcggt cgacaaacgc
    54001 tggtatacct caggcgtcat gctgttgata atgtcatcaa gattcataat ttttccgctc
    54061 ctgtggaata agttgctgaa tcgttttttc aaccgttgat ttcttcgccg ttttcgccat
    54121 cagtgaagcg taaagaagca gagttaacac aataacgttc gcccgttggc tgcggcccgt
    54181 caggaaagac atggcccaga tgggcatcgc agttaccgca acgaatttct atgcgctgca
    54241 ttccatgtga caagtctttg atataacgaa tagattcttc actcaccggt tcgtagaaac
    54301 tgggccagcc acagccggaa tcatacttgg tttgggaatg aaacagcggg gcatcgcaga
    54361 tcaaacagtg atatacgccg tcacgcttgt tatgcagtaa acgacccgta aatggcggtt
    54421 ctgtcccatg attctgcgtc acgtagaact gcatctcgga caaatttttt ttcagttctt
    54481 ctgccgaagg tttattagcc atttgctcac atctcacttt aatcgtgctc acattacgtg
    54541 actgattcta acaaaacatt aacaccaact ggcaaaattt tgtcctaaac ttgatctcga
    54601 cgaaatggct gcacctaaat cgtgatgaaa atcacatttt tatcgtaatt gccctttaaa
    54661 attcggggcg ccgaccccat gtggtctcaa gcccaaagga agagtgaggc gagtcagtcg
    54721 cgtaatgctt aggcacagga ttgatttgtc gcaatgattg acacgattcc gcttgacgct
    54781 gcgtaaggtt tttgtaattt tacaggcaac cttttattca ctaacaaata gctggtggaa
    54841 tatatgacta tcaaagtagg tatcaacggt tttggccgta tcggtcgcat tgttttccgt
    54901 gctgctcaga aacgttctga catcgagatc gttgcaatca acgacctgtt agacgctgat
    54961 tacatggcat acatgctgaa atatgactcc actcacggtc gtttcgacgg taccgttgaa
    55021 gtgaaagacg gtcatctgat cgttaacggt aaaaaaatcc gtgttaccgc tgaacgtgat
    55081 ccggctaacc tgaaatggga cgaagttggt gttgacgttg tcgctgaagc aactggtctg
    55141 ttcctgactg acgaaactgc tcgtaaacac atcaccgctg gtgcgaagaa agtggttatg
    55201 actggtccgt ctaaagacaa cactccgatg ttcgttaaag gcgctaactt cgacaaatat
    55261 gctggccagg acatcgtttc caacgcatcc tgcaccacca actgcctggc tccgctggct
    55321 aaagttatca acgataactt cggcatcatc gaaggtctga tgaccaccgt tcacgctact
    55381 accgctactc agaaaaccgt tgatggcccg tctcacaaag actggcgcgg cggccgcggc
    55441 gcttcccaga acatcatccc gtcttctacc ggtgctgcta aagctgtagg taaagtactg
    55501 ccagaactga atggcaaact gactggtatg gcgttccgcg ttccgacccc gaacgtatcc
    55561 gtagttgacc tgaccgttcg tctggaaaaa gctgcaactt acgagcagat caaagctgcc
    55621 gttaaagctg ctgctgaagg cgaaatgaaa ggcgttctgg gctacaccga agatgacgta
    55681 gtatctaccg atttcaacgg cgaagtttgc acttccgtgt tcgatgctaa agcgggtatc
    55741 gctctgaacg acaacttcgt gaaactggta tcctggtacg acaacgaaac cggttactcc
    55801 aacaaagttc tggacctgat cgctcacatc tccaaataag ttgagatgac actgtgatct
    55861 aaaaagagcg acttcggtcg ctcttttttt tacctgataa aatgaagtta aaggactgcg
    55921 tcatgattaa gaaaattttt gcccttccgg tcatcgaaca aatctcccct gtcctctccc
    55981 gtcgtaaact ggatgaactg gacctcattg tggtcgatca tccccaggta aaagcctctt
    56041 ttgcattaca gggcgcacac cttctctcgt ggaaacctgc gggtgaagaa gaagttctgt
    56101 ggttgagtaa caacacaccg ttcaaaaatg gcgtcgccat tcgcggtggc ataccggttt
    56161 gctggccgtg gtttggtccg gctgcacaac aaggtctgcc tgcgcacggt tttgcccgca
    56221 acctgccgtg gacgctgaaa tcacatcgtg aagatgctga tggtgtagcg ctgacttttg
    56281 aattgacaca aagcgaagag acgaaaaaat tctggccgca cgactttacg ctgttagcgc
    56341 atttccacgt gggtaaaacc tgtgaaatcg atcttgaagc acacggcgaa tttgaaacta
    56401 cctctgctct gcatacctac tttaacgtgg gtgatatcgc taaggtaagc gtcagtggac
    56461 taggcgatcg cttcattgat aaagtaaatg acgcgaaaga agatgtactg accgacggta
    56521 ttcagacctt ccctgaccgt accgatcgcg tgtatctgaa tccgcaagat tgcagcgtaa
    56581 ttaatgacga agcgctgaat cgtattatcg ccgtaggcca ccagcatcat ctgaacgttg
    56641 taggctggaa cccaggaccg gcgctttcag ttagcatggg cgatatgccg gatgatggct
    56701 acaagacctt tgtttgtgta gaaacggctt acgcttcaga aacgcaaaaa gtcaccaaag
    56761 agaaacctgc acatctggcg caatccattc gcgttgctaa acgttaattt gcgttaatat
    56821 tgtgtgccgg gtgcgatgca tccggcacga atcaacatca caccatatcc agcgcagttt
    56881 ttccttttgg tgccggatac gctttatcca gcataactaa ttccgctgac gaaagttcaa
    56941 cctcaagcac agccgcattt tgttggacat gtgcgacagt tgccgctttt ggaatcgcca
    57001 tcacaccctg atggctgatt acccacgcca acaatacttg tgccgcactg atattgtgag
    57061 catgtgcaat ttcgttgact accgcatttt ttaacagtcc attgcgcaac cgcccggcct
    57121 gggctaatgg actgtaagcc atcaccggca tctgctgttt ctggcaccag ggaagtagat
    57181 cgtactcaat ccctcgtgaa ccgagatggt aaagcacctg attagtggca cactgatttc
    57241 cccccggcag ctgccagagt tcctgcatat cggcataatc aaggttagaa acgccccagc
    57301 ggcggatttt tccctgggcg atcaattttt ccatcgctgc gacagtctct tcgagagcga
    57361 aactgccaga ccagtgtaat aagtagagat cgagataatc agtattgaga cggcgtaaac
    57421 tggcttcgca tgcatttatc gctttttgcc cgccagcatt ccacggatag actttagaga
    57481 cgagaaagac gttctcacgc agaccgatta atgcttcccc aaccactttt tcggcaccgc
    57541 catcggcata catttcggcg gtatcaatga gggttaaacc gagttcaatg cccgcgcgta
    57601 gtgcagcaac ttctgtttta cgctgactgg catcttcgcc catataccat gttccctgcc
    57661 ctatggctgg cagtgagaca tcgccactaa attgaatcat tttttgttgc attgtttcct
    57721 cccaggtatt gcaccaccgt aatgcaaaac agggcattac gccctgtttt tatgcacaaa
    57781 atgccctgga aagatgcatt atcagaattt gtaggtgatc ccggtagaaa tcaggccagt
    57841 ccaggattta tccaccattg ggctgtcagt aacttcatca gacagacggg tgtagcgcgc
    57901 ggtaccgtaa acactccagt cgccgaggaa gttgtagctg gcgctcagct ccaggtaagg
    57961 gctccagctg tcgttcgggt tatagccacg cagaccgctg cgagcggact ctttgcgcga
    58021 tacgccataa tagtattcgt tctggttttc gctgttccac tgcacaccaa tacccggagt
    58081 cacggtcagg ccaccgttgg tgtaacgata caaccaggcc atatcccaga cgatgccgtt
    58141 gctgttatcc agggtatcgc cagccagggt ggtacgcagg taaccgtact gggtaaagtg
    58201 agcataagac agaccagcca tcatggtgct cttacggtca tcgaggtgac gcatttggtg
    58261 atcgccactg tctttagctt tgaagtaaag cggcgaccag taagcggtaa ttgaaagttt
    58321 gtccgtcgcg tcattccaca ggtagtaacc accacctaag ccacggaacc agaagttatc
    58381 gccttcatag ttgattaccg gtactgggta aacatcggta tcgtaatctt tatatgggtg
    58441 ttcaacgaca cctacgcctg cgcccaggga aaatttacct tcagcgtgcg ctacgcctgc
    58501 agacgttgcg ataagcactc caagtgccag aagtttgagt ttggtcacaa ttaatcattc
    58561 cttaaacaaa tgtttagcgg gcgacaaagt ttacccgtca atacatcgaa acccaacctt
    58621 tttacgtttt cattttttat agtaactgtt taattttcct gacgcagatg acaccacgct
    58681 tacagccaaa tgaatttagc gttaccggcg accctattat ttacattaat tatgcaaaat
    58741 ttatggatga gttgttgata tgccattgaa attaagaaag ccgtgcaggc aagttttcca
    58801 tttgccatct acgcttaatt ttgaaggtgt atcaccgggc acgttgttct catcgtcaat
    58861 aaaatggcat gagagttgct gtgttttagc aagagacgtc gttcagttta cctcttccgg
    58921 gagcctctac tattcatatg aacggctctt aacctgtgct aaaaaacgaa aggacggcat
    58981 accatgaata tattcgatca ctatcgccag cgatatgaag ctgccaagga cgaagagttc
    59041 acactgcagg agtttcttac cacttgtcgg caagatcgca gtgcttatgc caacgcggct
    59101 gagcggctat tgatggctat tggtgagcct gtcatggtcg atacagccca ggaacccaga
    59161 ctttctcgac tcttttctaa ccgggtcatt gcacgttatc cggcgtttga agagttttac
    59221 ggcatggaag acgcgattga acagattgtt tcttatctga aacacgcggc tcaggggctg
    59281 gaagagaaga aacaaattct gtatctgctg gggcctgtgg gtgggggtaa atcatcactt
    59341 gctgagcgac tgaaatcatt aatgcagctc gtaccgattt atgtattgag cgccaacggt
    59401 gagcgtagcc cggtcaacga tcatccgttc tgtcttttca atccgcagga agatgcgcag
    59461 attctggaaa aagagtacgg cattcctcgc cgttatctcg gcaccatcat gtcgccgtgg
    59521 gcggcaaagc gcctgcatga atttggtggc gatatcacta agttccgggt agtgaaggtc
    59581 tggccgtcaa ttctgcaaca aattgccatc gccaaaacgg aacccggaga tgagaacaac
    59641 caggacatct ccgccctggt agggaaagtc gatattcgta aactcgaaca ctacgcgcag
    59701 aatgacccgg acgcctacgg ctattccggt gcgctgtgcc gcgccaatca ggggatcatg
    59761 gaatttgtcg agatgtttaa agcaccgata aaagtgctgc atcccttgtt aaccgccacc
    59821 caggaaggta actacaacgg gacggaaggt atctccgccc tgccgttcaa cgggattatt
    59881 ctcgcccact cgaacgaatc cgaatgggtc actttccgta ataacaaaaa caacgaagcc
    59941 ttcctcgacc gtgtttacat cgtgaaggtg ccgtattgct tgcgcatttc cgaagagatc
    60001 aaaatctacg agaaattgct taatcacagt gaattgactc acgccccctg cgcccctggc
    60061 acgctggaaa cgctgtcacg tttttctatt ctttcgcgtc tgaaagagcc agaaaactcc
    60121 agcatttatt caaagatgcg cgtttatgat ggtgaaagtc tgaaagacac tgatcccaaa
    60181 gccaagtcgt atcaggaata tcgtgactac gccggtgtcg atgaagggat gaacggtctg
    60241 tcgacgcgtt ttgcgtttaa gatcctctcc cgcgtgttca acttcgatca tgtagaagtg
    60301 gcggcaaacc cggtccatct gttctacgtc ctggaacagc agatcgagcg cgagcagttc
    60361 ccgcaagagc aggctgaacg ctatctggag ttcctgaaag gttatctgat cccgaaatat
    60421 gccgagttta tcggcaaaga gatccagacg gcctaccttg aatcctattc agaatatggg
    60481 caaaacattt tcgaccgtta tgttacctac gcggatttct ggattcagga tcaggagtat
    60541 cgcgatccgg ataccgggca gctgtttgac cgcgagtctc ttaacgccga gctggagaaa
    60601 atcgagaaac cggcggggat cagtaatcca aaagatttcc gcaacgagat tgttaacttc
    60661 gtactgcgag ccagagcgaa taacagcgga cgcaatccga actggaccag ctatgaaaaa
    60721 ctgcgcacgg ttatcgagaa gaaaatgttc tccaataccg aagagctgtt gccggttatt
    60781 tcgtttaacg ccaaaacgtc aaccgacgag cagaagaaac acgacgactt tgtcgaccgt
    60841 atgatggaaa aaggctacac ccgtaaacag gtgcgtttac tgtgcgaatg gtatttgcgc
    60901 gtacgtaaat cgtcttaaca accctggccc ggtacacatg ctaccgggcc tacaacgaca
    60961 gcgaaccgtg ggccagagaa gcggcaacac aagcgtagca taccgttggc aaatgtagta
    61021 cggggggcat atgacctggt ttattgaccg gcgtctgaac ggcaaaaata aaagcatggt
    61081 gaatcgccag cgtttcttac gccgttataa agcgcaaatt aaacagtcga tctccgaggc
    61141 cattaataag cgttcggtga ctgacgtcga cagcggcgag tccgtatcca ttcccacgga
    61201 agatattagc gaaccgatgt ttcatcaggg gcgtgggggc ctgcgccacc gtgtgcatcc
    61261 gggcaatgac catttcgtcc agaacgaccg aattgaacgt ccccagggtg gtggcggagg
    61321 ttccggcagt ggtcagggcc aggccagcca ggatggtgaa ggtcaggatg aatttgtctt
    61381 tcagatttcg aaagatgagt atcttgatct gctctttgaa gatttggcct taccgaatct
    61441 gaaacaaaac caacaacgcc agctgaccga atataaaacg catcgggcgg gttataccgc
    61501 taacggcgtt ccggccaata tcagcgttgt acgttcattg cagaactcac tggcgcggcg
    61561 cacagctatg acggcgggca agcggcggga acttcatgcg ctggaagaga atttggccat
    61621 catcagcaac agtgaacctg cgcaactgct ggaagaggaa cgtctgcgca aagaaattgc
    61681 agaattacgt gccaaaattg aacgcgtccc tttcattgac accttcgatt tacgttacaa
    61741 gaactacgaa aaacggcccg atccctccag ccaggcagtg atgttttgcc tgatggacgt
    61801 ttccggttca atggatcagt ccactaaaga tatggctaaa cgtttttata ttctgctgta
    61861 tctgttcctc agcagaacgt ataagaacgt ggaagtcgta tacatccgcc atcataccca
    61921 ggcgaaagaa gtcgatgaac atgagttttt ctactcgcag gaaactggcg gcaccattgt
    61981 ttccagcgcc ctaaaactga tggatgaggt agtgaaagag cgttataacc cggcacagtg
    62041 gaatatttac gcagcccaag catcagacgg cgataactgg gccgatgact ctccgctttg
    62101 ccatgaaatt ctggcgaaaa aaatattacc cgttgttcgt tattacagct atatcgaaat
    62161 tacacgtcgc gcgcatcaga cactgtggcg agaatatgag catctgcaat ctactttcga
    62221 caactttgcg atgcagcata tccgcgacca ggatgatatt tatccggtgt tccgtgaact
    62281 gtttcataaa caaaatgcaa cagctaaaga ctaaaactgt cagccgggtc attatcgcct
    62341 ggctgatttt tagctcactg taaattatct cttttattac atacattagc ttacaatcgc
    62401 tttaaatatg acagcataac ctttacacaa tttagttcca gaaaacaatc attcggaaaa
    62461 atgattcggt caacacgtat ttccctgggg ttattcttta attatttttt atcgttaacg
    62521 aaaattgatc ttggtcaaaa ctatatatct ctgccatcaa taaaatccag cactcacatt
    62581 gctctccttt ttatggcttc tatgggtaca caaaaattaa aagctcaagg cttttttatt
    62641 ttcagcttat tgctgacgtt aattttattt tgcattacta ccttatataa cgaaaacacg
    62701 aatgtaaaac tcatcccaca gatgaattac ctgatggttg ttgtggcttt gtttttcctt
    62761 aacgccgtca tttttctttt catgttaatg aagtatttca ctaacaaaca aattttacca
    62821 acactcattt taagccttgc atttttaagt ggccttatct atttagttga aaccattgta
    62881 attatccata aaccaatcaa cggcagtaca ctgatccaga caaagtcgaa tgatgtttct
    62941 attttctata ttttccgcca actcagtttc atttgtttaa cctcgctggc gctcttttgt
    63001 tatgggaaag acaacatcct tgacaacaat aagaaaaaaa ctggcattct gttgctggcg
    63061 ctgattcctt ttttagtttt tccccttctg gcacacaatc tgagcagtta taacgctgac
    63121 tattctttgt atgtcgtcga ttactgcccg gacaaccata ctgcgacctg gggaatcaac
    63181 tatacaaaaa tattggtttg tttgtgggca tttttactgt tctttattat catgcgtaca
    63241 cgattagcca gcgaactatg gccgttaata gcattattat gtctggcatc gctatgctgc
    63301 aacttacttc tactgactct ggatgagtat aattacacca tctggtatat cagtcgcggg
    63361 attgaagttt ccagtaaact gtttgttgtg tcttttctga tttataacat ttttcaggaa
    63421 ctgcaactct ccagcaaact ggcagttcat gatgtgctga ccaatattta taatcggcgc
    63481 tactttttca acagcgtaga gtcattattg tcgcgacctg ttgttaagga cttttgtgtc
    63541 atgctggttg atattaatca gttcaaacgc atcaatgccc aatggggaca tcgtgtgggt
    63601 gataaagtgc tggtatcaat tgtcgatatt atccagcaaa gcatccgccc cgatgatatt
    63661 ttagcgcgac tggagggtga ggtgtttggc ttgctattta ccgaactcaa tagtgcccag
    63721 gcaaaaatca ttgcggaacg tatgcgtaaa aatgtcgaac tcctgaccgg ctttagtaac
    63781 agatatgatg ttcctgaaca aatgaccatc agtattggca cggttttttc aacgggtgac
    63841 acgcataata tctcgcttgt catgacggaa gcagataaag ccttacgcga agcgaaaagc
    63901 gaggggggca acaaagtgat tattcatcat atttaagtgc aaaaatattc acagccatgc
    63961 tttttgcgtg gcttttgcat acaatttatt actattaccc ctaaatttcc cctccccagc
    64021 ggcgcagaga tgagtataat tagcgcccct gtgccaggcc gcaatcgaac tttatctggt
    64081 tttctcgttt cactaaccga aggagtgcca tttatcatga aattgcacca tagaatgctc
    64141 cggcatttta tcgccgcaag tgtcattgtg ctgacatctt ccttccttat ttttgaactt
    64201 gtcgccagcg acagagcaat gagtgcctat ctgcgctata tcgtgcagag agcagactct
    64261 tcctttcttt atgataagta tcagaatcag agtattgccg cgcatgtgat gcgcgctctc
    64321 gctgctgagc agtcggaagt accgccagaa caacggcgcg ctatctgcga ggcttttgag
    64381 tctgccaata atacccatgg cttaaacctg actgctcata aataccaggg cttacgcggc
    64441 acactacaaa ccgcatccac tgactgcgac acaattgtgg aagctgcagc actattaccc
    64501 gcttttgatc aggcagtgga aggcaaccgc caccaggatg attacggttc aggtcttggg
    64561 atggccgaag agaaatttca ctattatctc gatctcaatg accgctatgt ctatttttat
    64621 gagccggtta atgttgaata ctttgcgatg aataactggt ccttcctgca atcaggaagt
    64681 attggtatcg atcgcaaaga tattgaaaaa gtatttaccg ggcgtaccgt attatcgagc
    64741 atttaccagg atcagcgtac taaacagaac gtgatgagtt tgctgacgcc ggtatatgtc
    64801 gcagggcagc taaaagggat tgtgctgctg gatattaaca aaaacaatct gcggaatatc
    64861 ttttacactc atgaccgccc tctcctctgg cgttttctca atgtcacgct aaccgataca
    64921 gattcggggc gcgacattat catcaaccag agcgaagata atctgttcca gtatgtcagt
    64981 tacgtccatg acttaccggg cggcattcgt gtctcgttat ccattgatat tctttacttt
    65041 atcacgtctt cgtggaaaag cgttctgttc tggattttga cggcgttaat tttgctgaat
    65101 atggtgcgga tgcacttccg cttataccaa aatgtgtcgc gagaaaatat tagtgatgcg
    65161 atgactggac tctataatcg caaaatttta acccctgaac tggagcagcg gttgcagaaa
    65221 ctggtgcaat ccggttcttc ggtgatgttt attgctattg acatggacaa gttaaagcaa
    65281 ataaatgaca ccctcggtca tcaggagggg gatttagcga ttacgttatt agctcaggcg
    65341 attaaacagt cgattcgtaa aagtgattat gccatccgac tcggtggcga tgaattctgc
    65401 atcattcttg tcgattcgac gccgcaaatt gcagcacaac tgcctgaacg tatcgaaaaa
    65461 cgtctgcaac atatcgcgcc gcagaaagag atcggcttct cttccggtat ttacgcgatg
    65521 aaagaaaacg atacgttaca tgatgcgtat aaagcttccg atgagcgttt atatgtcaat
    65581 aagcagaaca aaaacagccg ttcatgataa ccttctgtgg ttgtttgctt gtaatctcag
    65641 gagcatgaaa tgactgaaat ggctaaagga agcgtgacgc atcagcggtt aatcgcttta
    65701 ttatcacaag aaggtgctaa cttccgcgtc gttacccatg aagcggtagg taaatgtgaa
    65761 gcagtgtcag aaattcgtgg caccgcttta ggccaggggg ctaaggcact ggtatgtaaa
    65821 gtcaaaggca atggcgtaaa tcaacatgtt ctggcgatcc tcgctgccga tcaacaggcc
    65881 gatctgagcc aactcgccag ccatataggc ggattacgcg cttcgttggc cagcccggcg
    65941 gaagtcgatg aactcacagg ctgtgtcttc ggcgcgatcc cccctttcag cttccatcca
    66001 aaactcaaac tggttgccga ccccctactc ttcgaacgat ttgatgaaat cgccttcaat
    66061 gcaggcatgc tggataaatc cgttattttg aaaaccgcgg attatttgcg tattgcgcaa
    66121 ccagaactgg tcaatttccg ccgcactgcg taactagcct gtccgttcaa taagcagaac
    66181 ggacaaaacc agcacagcag caatggcaaa aaacgatgac gtgataatca gtgtctcgac
    66241 gaacatttga tcgttcatag tatgcccccg ggagatagct gttttcacgt tattgttaac
    66301 gtacacaaat ggcagtttga tgacagttcg tctgattttt tatgcaaaaa acgtaaagat
    66361 tttctacttc ctgcctgcag caagcgtaaa gtaagcaggc ttattatttt ttggcaagga
    66421 aaccacgatg tttgatgtca ctttgctgat cctgctcggg ttagctgcgc tgggctttat
    66481 cagtcataac accactgtcg ccgtttcaat tctggtgttg attattgtcc gcgtcacacc
    66541 gttaagcacc tttttcccgt ggattgaaaa acaggggcta agtatcggga taatcattct
    66601 gacgattggc gttatggccc ccatcgccag cgggacgcta ccgccctcaa ccctgattca
    66661 ctcgtttctg aactggaaat cgctggtggc aattgcagtc ggcgttattg tctcctggct
    66721 gggggggcgc ggcgtgacgt taatgggcag ccagccgcaa ctggtcgccg ggctgctggt
    66781 gggcactgtt ttaggcgtgg cgctgtttcg cggcgtaccg gttggcccgc ttattgccgc
    66841 gggtctggtt tcgctgattg tggggaaaca gtagttaatc ccgcaatata tcggcctggc
    66901 gtttgcccca ggcctttctt aaacatagta ataaaggccg ttgttgaatc ataccccagt
    66961 gtatgagcaa ctttctgtac agtatcgcct ttcactaatc cctgaagcgc cataatcagc
    67021 tgtaactgct gacgccactg gcgaaaactc aaccccgtct ctttcactat cagccgggca
    67081 agattgcgtt cactcatcgc aaaaaagcca gcccattgcc tcaatgagcc ccactcgacg
    67141 ggctctttcg ccatcatctc caccatcgtg cggattttag gatgagaaga accgggcaag
    67201 tgcagctgtt gttgtggttg ctgagggagt tcatcaaaca ggacctgaat taatctgcgg
    67261 gtcatcggct cagcacgctg agtcgtcgtc ctgtttgcca gggttaaaat taattcccgg
    67321 cataagggcg atattttcaa tgtgcaacat gttgtcggca ttgtcactgc gctgggctcg
    67381 ataaacagaa aacagagttc ggcgttagct gtcacttgat tactatgttt caccccgccc
    67441 ggtatccaaa ccgcatattg tggcggcacc atccacaaag cattttctac cgtacaggta
    67501 attgcaccat gtagtgccag tatcaactgc cctttgcggt gctgatgtac aggactggtt
    67561 aactcatccg ttccggcgtg aatacaaaat gcgaccgcgg cttcatggtg tcggtcgggt
    67621 tcatagccat tgagattcaa cctgtgcatc attttgtccg aatttagcga tattttgtca
    67681 ttttagcttg attcaacata acaataaaaa cggtaaggta cagcctcgtt tgtaacaatg
    67741 agaagcatat gacctgttca acttcattaa gcggtaaaaa caggattttc cttatcgctg
    67801 gcattctgat gattgccaca acattacgcg tcacctttac cggcgcagca ccgttactgg
    67861 atacgattcg ttccgcttac tcgctaacga cggcgcaaac cggcttattg accaccctgc
    67921 cattattagc ctttgcgctg atctcaccgc tggccgcccc ggtggcgcga cgttttggta
    67981 tggaacgtag cctgtttgcc gcgttacttt tgatctgtgc aggtatcgca attcgctctc
    68041 tcccttcgcc ttacttatta tttggcggta cagcggtcat tggcggtggg attgcattag
    68101 gcaatgtctt actgccagga ttaattaaac gcgatttccc tcattccgtc gccagactta
    68161 ccggcgcata ttccctgaca atgggagctg cggcggcact gggatcggcg atggtagtgc
    68221 cgctggcttt gaacggtttt ggctggcaag gcgcgttgct catgctgatg tgttttcctc
    68281 tgctggctct ttttttatgg ctgccacagt ggcgaagtca acaacatgca aatttgagta
    68341 cctcacgcgc cttacatact cggggtatct ggcgttcgcc gcttgcctgg caggtaacat
    68401 tgtttcttgg gatcaactca ctggtctatt acgtgattat tggctggctt ccggcgatcc
    68461 tcatcagtca aggctatagc gaagcacagg cgggttcact gcatggtttg ctgcaactag
    68521 ccacagcagc tcccggtttg ctgatcccac ttttcttaca tcatgtgaaa gatcagcgtg
    68581 gtattgcagc gttcgttgcc ttgatgtgcg cagtgggcgc ggttgggctc tgctttatgc
    68641 cagcacacgc gatcacctgg actctgcttt tcggttttgg ttccggcgca acaatgatac
    68701 tggggttgac gttcattggt cttcgggcaa gttctgcgca tcaggcggcg gcactctcgg
    68761 ggatggcaca atccgtcggg tatttgctgg cagcctgtgg gccgccgctg atgggtaaaa
    68821 tacacgatgc taacggtgac tggtccgtac cactgatggg tgttgcaata ctttcactac
    68881 tgatggcgat tttcggactt tgcgccggga gagacaaaga aattcgctaa tatccggtgc
    68941 tatagtgacg tgacaaatca tgcgtgaaag ggagaacaaa tacgatgaat attcagtgca
    69001 aacgcgttta tgatccggct gaacagagcg atggttatcg cgtactggtc gaccgcctct
    69061 ggccacgcgg tatcaaaaaa accgatttag cccttgatga gtggaataaa gaaatcacgc
    69121 cgtcaacgga gctgcgcaaa gcctttcacg gcgaagtcgt cgattttgca acctttcgcg
    69181 agcaatatct tgcagaactg gcgcaacacg agcaagaagg aaagcggctg gcagacatcg
    69241 ccaaaaaaca gccgctgacc ctgctctact cagcaaaaaa caccacgcag aaccatgcgc
    69301 tggtgctggc agactggcta cgtagcttgt gattttagta cagcatccgg cggttatttt
    69361 tcaccagccg gatggtcccg tcgccacaat gcccattcat caatcgtttc accgcccggt
    69421 aatttgcaat tgttgctgac cccttgcgct gtctgcacag gaatgagcgt cccgcccttc
    69481 tgctggcaat agaccgacgc cggatttgcc ataccaatct gcggcggttt aggtgcttct
    69541 ggctgagaag gggttgaaca accagccagg accagcaagc aaggcagaac aaaactgata
    69601 attttcattt attgatctca catatttatc caggcttaga gtatcgcggt atcgttttgt
    69661 tttgcagcac tatttttatt acattcactc aaaacatatt acgccttgtt tcatctttgt
    69721 tgatgatgtt ttatcatgcc tgcaaagatt aaataatcag catttacccg ccgtatcctg
    69781 gagttgtttc gtgtcagatc agattatcgc ccgcgtctcg caatcccttg ccaaagaaca
    69841 gtcactggaa agtctggttc gacagcttct ggagatgctg gaaatggtca ctgatatgga
    69901 gtcaacctac ctgaccaaag tggatgtcga agcgcgcctg cagcatataa tgtttgcccg
    69961 taatagccag aaaatgcaca tcccggagaa ttttaccgtc tcgtgggatt actcgttatg
    70021 caaacgcgcc attgatgaaa actgtttttt cagcgatgaa gtccccgacc gttggggcga
    70081 ctgtattgcg gcacgcaatc ttggcatcac cacatttctg agcacgccaa ttcacttacc
    70141 ggatggatca ttctatggca cgctttgcgc cgccagcagt gagaagcgcc agtggagtga
    70201 acgcgcggaa caggtcttac agttattcgc cggactgatt gcacaatata ttcaaaaaga
    70261 ggcactggtt gaacagctgc gcgaagctaa tgctgcgctg attgcgcaat cgtataccga
    70321 ctcgttaacc gggctaccga atcggcgggc gatttttgaa aatctgacga cgctgttttc
    70381 tctcgcccgg catcttaacc ataagataat gatcgcgttt atcgatctgg ataacttcaa
    70441 attaatcaat gatcgttttg gtcataatag tggcgatctg tttctcattc aggttggcga
    70501 gcgccttaat acgctccagc aaaatggcga agttattggt cgtctcggcg gtgatgagtt
    70561 tttggttgtt tcactgaaca acgagaatgc ggatatttcg tcgctgcgag aacgtattca
    70621 acaacaaata cgcggagaat atcacttagg tgatgttgat ttgtattatc ctggtgccag
    70681 tcttggcata gtagaagtcg atcctgaaac gaccgatgca gacagtgccc tgcatgctgc
    70741 cgatatcgcg atgtatcagg agaaaaaaca taaacagaaa acaccttttg tcacgcattc
    70801 agcgctacat tcctgaggcg tattcacatc cttttgattg gtgataacat gcgaatcggt
    70861 attatttttc cggttgtaat ctttattaca gcggtcgtat ttttagcatg gttttttatt
    70921 ggcggctatg ctgccccggg agcataaaga tgaaaaaaac aacgattatt atgatgggtg
    70981 tggcgattat tgtcgtactc ggcactgagc tgggatggtg gtaacgtcac atctaaaaaa
    71041 tagcaaaggc tgcctgtgtg cagcctttgt gcaatttacg cgttaacttt taatcttcct
    71101 gtagataaat agcacaacaa tcgcaccaat aacggcaacc acgaagctgc caaaattgaa
    71161 gccatcgact ttaccaaagc caaacagcgt gctgatccat ccgccgacta cggcaccgac
    71221 tatccccagc aggatagtca taaagaatcc accaccatct ttacctggca tgatccactt
    71281 cgccagaata ccggcaataa gcccaaaaat aatccatgac agaatgccca ttgtttcctc
    71341 acttatctgt tttgcattag cgggttagtc gctgataaaa agcatagcac aacatcggga
    71401 ggggaagatt tgtgacgagc atcacggagg aattttttgc gatggcgcag aaattgcgcc
    71461 atcaacgatc agtgataatt accaaccaca aacatcatgt tcgttttccg tgtcataaga
    71521 acgcacggta ttcaccagat cttttatcac ttcagccgcc acttctggca ccagcaaagt
    71581 catcggcgtc tctgtttcat aatcgacaga aacgccattg ctgttattgg tgacggtcac
    71641 ggtatacgtt gctttgccca tgattcattt cccgttatga atgactttcc gttgttgcgc
    71701 gccttccatc aggacttcag gagcaacgaa gaagtcaatg ttgaaataag tatcgtcagt
    71761 catggcttca atgttgtgcc acttttctgg agggaacacc gcaaactgcc ccgcttcgat
    71821 aaggatcacc tgatcaggct ctgcactgtg ttcatcagcg tagccgagat atttgaccgc
    71881 cccatgcata acggaaaggc gtgggtaaac ccccgggcgc gttcctttat caagatgacg
    71941 ttcgaatatt ccggcaggcg cagtttgttt attccagaaa ggcgttgagc gcgtatgaat
    72001 ataattctgt gggatttgca gcatcctttt ccctccttcg gtgaatgcgc tggaaacggt
    72061 ttattccagc cgtttcaggg tacgcctgat aatttgcatt ttaaatacca tttattggtt
    72121 actttttagc accgtatcag agaagaatca gggaggatta caggtgggaa gcccgcggca
    72181 acgcgggctg aaagcatcag gattgcagcg tcgccagtcg ggcggcgaaa cccacgaaca
    72241 tcaaaccaat cagtgagttg cccactttag ccagtttctt tttggtacgt atgtactgcg
    72301 tgacaaaagc cccagaaata atcaggaagc tcaaatagca gaaactcacc agttccagcg
    72361 tcgtcgccag aataaagaat gaaattcccg tatgtggggc attaacatcg ataaactgta
    72421 cgaaaaacga cacatagaac aaaatggctt tcggattagt caggctcaaa attaacgcgc
    72481 gtttaaaaat ggcaccgtat tggggctcat cggatttggt ctcgctattt ttacctttca
    72541 gggtcgcgta gagaatttta ctccccagat agagcaaata aaacgcacca agataacgta
    72601 cgatgttgaa taatatcggg gtggtcttaa ttaatgtcgc cactccagcc catgccagaa
    72661 acatcaatac cgcatcgcca ataaatacac cacaggccgc aagataaccg cctttcatac
    72721 cgctactgac gctatttttg agtacaaaca gggtatttgg ccctggcacc aacacaataa
    72781 aaatggcccc aaccagatag gtccagtaat tcagaacccc gtattcagcg aacacattaa
    72841 cctctttaat tatctttcga tcatgcgcga ttaaaggtga atatgctaac caatctgtag
    72901 cggcttagaa aggagaaaat caggttttaa ctcgatatca acccgataat tgaatcatta
    72961 atcaggcatg ctccagtgaa aaattcgggt agtgctcggc aaaatactgg cgtaaaaatt
    73021 ctaccgttat ccgcactttc gctgacgtcg acagctttga aacataaacg gcccagacat
    73081 tcgctggctg gtaatattcc ggtagcactt gtactaaatg accactggcg ggaaacagcc
    73141 tggcgacatc gatttttacg tggtccggaa aaacaccgaa ggcgaatatt cctcgccagg
    73201 cggtagagtg aatgaaggaa cagagaatga agtcgtcatt caggaatcgg tatttactcg
    73261 tcgtggtgtc gagcgcattt ggcgttaagc tcaaataagt tcatttgaac cgcctg
//
LOCUS       DAPOXO010000011        72353 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPOXO010000011 DAPOXO010000000
VERSION     DAPOXO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 72353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72353
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.011"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            339..1910
                     /gene="garD"
                     /locus_tag="ROH59_000967"
     CDS             339..1910
                     /gene="garD"
                     /locus_tag="ROH59_000967"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HDX4803487.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLQKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            2059..2394
                     /gene="prlF"
                     /locus_tag="ROH59_000968"
     CDS             2059..2394
                     /gene="prlF"
                     /locus_tag="ROH59_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HDX4803488.1"
                     /translation="MPANARSNAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFDIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            2394..2858
                     /gene="yhaV"
                     /locus_tag="ROH59_000969"
     CDS             2394..2858
                     /gene="yhaV"
                     /locus_tag="ROH59_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ribonuclease
                     toxin YhaV"
                     /protein_id="HDX4803489.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVEALKGKDPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH"
     gene            complement(2913..3722)
                     /gene="agaR"
                     /locus_tag="ROH59_000970"
     CDS             complement(2913..3722)
                     /gene="agaR"
                     /locus_tag="ROH59_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HDX4803490.1"
                     /translation="MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            3971..5251
                     /gene="kbaZ"
                     /locus_tag="ROH59_000971"
     CDS             3971..5251
                     /gene="kbaZ"
                     /locus_tag="ROH59_000971"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HDX4803491.1"
                     /translation="MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPL
                     LIEATSNQVDQFGGYTGMTPAGFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDGIVAERAARLAKVAEETCR
                     EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWP
                     RIIALVVQPGVEFDHTNVIDYQPAKATALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLENVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGELQPTPRELIINHIQDILAQYHTACEGQ"
     gene            5274..5747
                     /gene="agaV"
                     /locus_tag="ROH59_000972"
     CDS             5274..5747
                     /gene="agaV"
                     /locus_tag="ROH59_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312038.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDX4803492.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL"
     gene            5758..6537
                     /locus_tag="ROH59_000973"
     CDS             5758..6537
                     /locus_tag="ROH59_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HDX4803493.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGTFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            6527..7405
                     /locus_tag="ROH59_000974"
     CDS             6527..7405
                     /locus_tag="ROH59_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDX4803494.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AVTVVLGIVGKFCHFL"
     gene            7423..7857
                     /locus_tag="ROH59_000975"
     CDS             7423..7857
                     /locus_tag="ROH59_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX4803495.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            7854..8987
                     /gene="nagA"
                     /locus_tag="ROH59_000976"
     CDS             7854..8987
                     /gene="nagA"
                     /locus_tag="ROH59_000976"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDX4803496.1"
                     /translation="MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDALDKLAMHKAREGVGSWLPTTVTAPLNTIHAA
                     LKRIALRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQQT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGHYTLCGEEVQMHGGIVRTAFGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLH
                     PARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF"
     gene            9337..10491
                     /locus_tag="ROH59_000977"
     CDS             9337..10491
                     /locus_tag="ROH59_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HDX4803497.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLQIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAITAESNDVIAAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVTIHPWQA"
     gene            10504..11364
                     /gene="kbaY"
                     /locus_tag="ROH59_000978"
     CDS             10504..11364
                     /gene="kbaY"
                     /locus_tag="ROH59_000978"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HDX4803498.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSRDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
     gene            11531..12007
                     /gene="agaB"
                     /locus_tag="ROH59_000979"
     CDS             11531..12007
                     /gene="agaB"
                     /locus_tag="ROH59_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDX4803499.1"
                     /translation="MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDD
                     IQQKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGIDL
                     KDVNVGNMHFSEGKKQISSKVYVDDQDLTDLRYIKQRGVNVFIQDVPGDQKEQIPD"
     gene            12046..12849
                     /gene="agaC"
                     /locus_tag="ROH59_000980"
     CDS             12046..12849
                     /gene="agaC"
                     /locus_tag="ROH59_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
                     /protein_id="HDX4803500.1"
                     /translation="MHEITLLQGLSLAALVFVLGIDFWLEALFLFRPIIVCTLTGAIL
                     GDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAKTAIGLGLP
                     FSLLMQYVILFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAVIAFLCT
                     YLAQGAMQALVKAMPAWLTHGFEVAGGILPAVGFGLLLRVMFKAQYIPYLIAGFLFVC
                     YIQVSNLLPVAVLGAGFAVYEFFNAKSRQQAQPQPVASKNEEEDYSNGI"
     gene            12839..13630
                     /gene="agaD"
                     /locus_tag="ROH59_000981"
     CDS             12839..13630
                     /gene="agaD"
                     /locus_tag="ROH59_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708938.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HDX4803501.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKNDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            13631..14398
                     /locus_tag="ROH59_000982"
     CDS             13631..14398
                     /locus_tag="ROH59_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HDX4803502.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIR
                     SKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQPLGLREDQLISFHSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTADRPVTRGITLGLKDILNAREVLLLITGEGK
                     QDATERFLTAKVSTAIPASFLWLHNHFTCVIDEMCRR"
     gene            complement(14448..15311)
                     /gene="rsmI"
                     /locus_tag="ROH59_000983"
     CDS             complement(14448..15311)
                     /gene="rsmI"
                     /locus_tag="ROH59_000983"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDX4803503.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEDDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQGE"
     gene            15376..17412
                     /gene="lpoA"
                     /locus_tag="ROH59_000984"
     CDS             15376..17412
                     /gene="lpoA"
                     /locus_tag="ROH59_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoA"
                     /protein_id="HDX4803504.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELVNQLPQELNDNQRREKT
                     LLAAEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PVPVSAPATSTAAVNAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATT
                     DSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATL
                     YASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMG
                     VDAWSLANHFSQMRQVQGFEINGNTGSLTASPDCVINRKLSWLQYQQGQVVPAS"
     gene            17370..17765
                     /locus_tag="ROH59_000985"
     CDS             17370..17765
                     /locus_tag="ROH59_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDX4803505.1"
                     /translation="MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVN
                     ERGGEIDLIMREGRTTVFIEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            17785..18375
                     /gene="diaA"
                     /locus_tag="ROH59_000986"
     CDS             17785..18375
                     /gene="diaA"
                     /locus_tag="ROH59_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HDX4803506.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV"
     gene            18385..18960
                     /gene="yraP"
                     /locus_tag="ROH59_000987"
     CDS             18385..18960
                     /gene="yraP"
                     /locus_tag="ROH59_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HDX4803507.1"
                     /translation="MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(19073..20113)
                     /locus_tag="ROH59_000988"
     CDS             complement(19073..20113)
                     /locus_tag="ROH59_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDX4803508.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWQPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPLLNPAT
                     LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLV"
     gene            complement(20186..20821)
                     /locus_tag="ROH59_000989"
     CDS             complement(20186..20821)
                     /locus_tag="ROH59_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312060.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDX4803509.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNVIAAPTRRPLGDMPGV
                     FNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLFRLLPGNWKSIDARDVARVMLAEAMRPEHEGVTILSSSELRKRAE"
     gene            20949..21467
                     /gene="yhbO"
                     /locus_tag="ROH59_000990"
     CDS             20949..21467
                     /gene="yhbO"
                     /locus_tag="ROH59_000990"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HDX4803510.1"
                     /translation="MSKKIAALITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVVIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIVIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(21447..21890)
                     /locus_tag="ROH59_000991"
     CDS             complement(21447..21890)
                     /locus_tag="ROH59_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HDX4803511.1"
                     /translation="METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFY
                     ILTEEKTRHAQMSGPQAAIAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYN
                     RRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRNSGTEQA"
     gene            21941..22243
                     /gene="yhbQ"
                     /locus_tag="ROH59_000992"
     CDS             21941..22243
                     /gene="yhbQ"
                     /locus_tag="ROH59_000992"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HDX4803512.1"
                     /translation="MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVTEGAGFAELLSSLQTPEIKSD"
     gene            complement(22230..22733)
                     /locus_tag="ROH59_000993"
     CDS             complement(22230..22733)
                     /locus_tag="ROH59_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX4803513.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLHCRWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(22727..23251)
                     /locus_tag="ROH59_000994"
     CDS             complement(22727..23251)
                     /locus_tag="ROH59_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HDX4803514.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            23460..24455
                     /locus_tag="ROH59_000995"
     CDS             23460..24455
                     /locus_tag="ROH59_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDX4803515.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQHAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            24464..25342
                     /locus_tag="ROH59_000996"
     CDS             24464..25342
                     /locus_tag="ROH59_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDX4803516.1"
                     /translation="MKYSLGPVLWYWPKETLEDFYQQAAASSADVIYLGEAVCSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            25423..26430
                     /locus_tag="ROH59_000997"
     CDS             25423..26430
                     /locus_tag="ROH59_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="luciferase-like monooxygenase"
                     /protein_id="HDX4803517.1"
                     /translation="MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELL
                     G"
     gene            complement(26548..27792)
                     /gene="mtr"
                     /locus_tag="ROH59_000998"
     CDS             complement(26548..27792)
                     /gene="mtr"
                     /locus_tag="ROH59_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HDX4803518.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAVGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMIVLIL
                     VFGVGNALVHILSSFNVLPVYQ"
     gene            complement(27946..29835)
                     /gene="deaD"
                     /locus_tag="ROH59_000999"
     CDS             complement(27946..29835)
                     /gene="deaD"
                     /locus_tag="ROH59_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HDX4803519.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(29828..29908)
                     /gene="yrbN"
                     /locus_tag="ROH59_001000"
     CDS             complement(29828..29908)
                     /gene="yrbN"
                     /locus_tag="ROH59_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HDX4803520.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(30015..30899)
                     /gene="nlpI"
                     /locus_tag="ROH59_001001"
     CDS             complement(30015..30899)
                     /gene="nlpI"
                     /locus_tag="ROH59_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HDX4803521.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(31008..33143)
                     /gene="pnp"
                     /locus_tag="ROH59_001002"
     CDS             complement(31008..33143)
                     /gene="pnp"
                     /locus_tag="ROH59_001002"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDX4803522.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKNAIRRIEEITAEIEVGRV
                     YNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(33390..33659)
                     /gene="rpsO"
                     /locus_tag="ROH59_001003"
     CDS             complement(33390..33659)
                     /gene="rpsO"
                     /locus_tag="ROH59_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDX4803523.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(33808..34752)
                     /gene="truB"
                     /locus_tag="ROH59_001004"
     CDS             complement(33808..34752)
                     /gene="truB"
                     /locus_tag="ROH59_001004"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDX4803524.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(34752..35153)
                     /gene="rbfA"
                     /locus_tag="ROH59_001005"
     CDS             complement(34752..35153)
                     /gene="rbfA"
                     /locus_tag="ROH59_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDX4803525.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(35317..37989)
                     /gene="infB"
                     /locus_tag="ROH59_001006"
     CDS             complement(35317..37989)
                     /gene="infB"
                     /locus_tag="ROH59_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDX4803526.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(38014..39501)
                     /gene="nusA"
                     /locus_tag="ROH59_001007"
     CDS             complement(38014..39501)
                     /gene="nusA"
                     /locus_tag="ROH59_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDX4803527.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA"
     gene            complement(39529..39981)
                     /gene="rimP"
                     /locus_tag="ROH59_001008"
     CDS             complement(39529..39981)
                     /gene="rimP"
                     /locus_tag="ROH59_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDX4803528.1"
                     /translation="MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(40188..40264)
                     /locus_tag="ROH59_001009"
     tRNA            complement(40188..40264)
                     /locus_tag="ROH59_001009"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(40228..40230),aa:Met,seq:cat)
     gene            40612..41955
                     /gene="argG"
                     /locus_tag="ROH59_001010"
     CDS             40612..41955
                     /gene="argG"
                     /locus_tag="ROH59_001010"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDX4803529.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ"
     gene            complement(41963..43588)
                     /locus_tag="ROH59_001011"
     CDS             complement(41963..43588)
                     /locus_tag="ROH59_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDX4803530.1"
                     /translation="MTVFNKFVKSFKSHWLLYLCVIIFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRIPSLPLRLLIAAPFVLLTAADMSISLYSWCIFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKEAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTHSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQKTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENNIFSTAYNNYIINAWMGVTKPEQPQTLEEVIAHYKGDS
                     RVVDANHDVFDYVMLRKEFTEDNQGNPTPEGQG"
     gene            complement(44045..44131)
                     /locus_tag="ROH59_001012"
     tRNA            complement(44045..44131)
                     /locus_tag="ROH59_001012"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44095..44097),aa:Leu,seq:gag)
     gene            complement(44146..44478)
                     /gene="secG"
                     /locus_tag="ROH59_001013"
     CDS             complement(44146..44478)
                     /gene="secG"
                     /locus_tag="ROH59_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDX4803531.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(44706..46043)
                     /gene="glmM"
                     /locus_tag="ROH59_001014"
     CDS             complement(44706..46043)
                     /gene="glmM"
                     /locus_tag="ROH59_001014"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDX4803532.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(46036..46884)
                     /gene="folP"
                     /locus_tag="ROH59_001015"
     CDS             complement(46036..46884)
                     /gene="folP"
                     /locus_tag="ROH59_001015"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDX4803533.1"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLLDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVCVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(46974..48908)
                     /gene="ftsH"
                     /locus_tag="ROH59_001016"
     CDS             complement(46974..48908)
                     /gene="ftsH"
                     /locus_tag="ROH59_001016"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDX4803534.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(49008..49637)
                     /gene="rlmE"
                     /locus_tag="ROH59_001017"
     CDS             complement(49008..49637)
                     /gene="rlmE"
                     /locus_tag="ROH59_001017"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HDX4803535.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            49763..50056
                     /gene="yhbY"
                     /locus_tag="ROH59_001018"
     CDS             49763..50056
                     /gene="yhbY"
                     /locus_tag="ROH59_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDX4803536.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(50212..50688)
                     /gene="greA"
                     /locus_tag="ROH59_001019"
     CDS             complement(50212..50688)
                     /gene="greA"
                     /locus_tag="ROH59_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDX4803537.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            50936..52369
                     /gene="dacB"
                     /locus_tag="ROH59_001020"
     CDS             50936..52369
                     /gene="dacB"
                     /locus_tag="ROH59_001020"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDX4803538.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVTTLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGIAWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(52410..53582)
                     /gene="cgtA"
                     /locus_tag="ROH59_001021"
     CDS             complement(52410..53582)
                     /gene="cgtA"
                     /locus_tag="ROH59_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HDX4803539.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAK
                     PRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(53598..54563)
                     /locus_tag="ROH59_001022"
     CDS             complement(53598..54563)
                     /locus_tag="ROH59_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX4803540.1"
                     /translation="MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFL
                     MASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWG
                     VIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLANPGVIAQLSHWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE"
     gene            complement(54690..54947)
                     /gene="rpmA"
                     /locus_tag="ROH59_001023"
     CDS             complement(54690..54947)
                     /gene="rpmA"
                     /locus_tag="ROH59_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDX4803541.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(54968..55279)
                     /gene="rplU"
                     /locus_tag="ROH59_001024"
     CDS             complement(54968..55279)
                     /gene="rplU"
                     /locus_tag="ROH59_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDX4803542.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            55538..56509
                     /gene="ispB"
                     /locus_tag="ROH59_001025"
     CDS             55538..56509
                     /gene="ispB"
                     /locus_tag="ROH59_001025"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HDX4803543.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            56742..57020
                     /gene="sfsB"
                     /locus_tag="ROH59_001026"
     CDS             56742..57020
                     /gene="sfsB"
                     /locus_tag="ROH59_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HDX4803544.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIAKALGTDPWVIWPSRYHDPQTHEFIDRTQLMRSYTKPKK"
     gene            complement(57068..58327)
                     /gene="murA"
                     /locus_tag="ROH59_001027"
     CDS             complement(57068..58327)
                     /gene="murA"
                     /locus_tag="ROH59_001027"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDX4803545.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(58382..58636)
                     /gene="ibaG"
                     /locus_tag="ROH59_001028"
     CDS             complement(58382..58636)
                     /gene="ibaG"
                     /locus_tag="ROH59_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HDX4803546.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(58796..59089)
                     /gene="mlaB"
                     /locus_tag="ROH59_001029"
     CDS             complement(58796..59089)
                     /gene="mlaB"
                     /locus_tag="ROH59_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HDX4803547.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEIREEAVKGITSIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(59089..59724)
                     /gene="mlaC"
                     /locus_tag="ROH59_001030"
     CDS             complement(59089..59724)
                     /gene="mlaC"
                     /locus_tag="ROH59_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HDX4803548.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQRDAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(59743..60294)
                     /gene="mlaD"
                     /locus_tag="ROH59_001031"
     CDS             complement(59743..60294)
                     /gene="mlaD"
                     /locus_tag="ROH59_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HDX4803549.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(60299..61081)
                     /gene="mlaE"
                     /locus_tag="ROH59_001032"
     CDS             complement(60299..61081)
                     /gene="mlaE"
                     /locus_tag="ROH59_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HDX4803550.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(61089..61898)
                     /gene="mlaF"
                     /locus_tag="ROH59_001033"
     CDS             complement(61089..61898)
                     /gene="mlaF"
                     /locus_tag="ROH59_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HDX4803551.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            62108..63085
                     /locus_tag="ROH59_001034"
     CDS             62108..63085
                     /locus_tag="ROH59_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDX4803552.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPREGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            63099..64085
                     /gene="kdsD"
                     /locus_tag="ROH59_001035"
     CDS             63099..64085
                     /gene="kdsD"
                     /locus_tag="ROH59_001035"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HDX4803553.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            64106..64672
                     /gene="kdsC"
                     /locus_tag="ROH59_001036"
     CDS             64106..64672
                     /gene="kdsC"
                     /locus_tag="ROH59_001036"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HDX4803554.1"
                     /translation="MSKAGASLATCYGPVSADVMAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            64669..65244
                     /gene="lptC"
                     /locus_tag="ROH59_001037"
     CDS             64669..65244
                     /gene="lptC"
                     /locus_tag="ROH59_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HDX4803555.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            65213..65770
                     /gene="lptA"
                     /locus_tag="ROH59_001038"
     CDS             65213..65770
                     /gene="lptA"
                     /locus_tag="ROH59_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HDX4803556.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            65777..66502
                     /gene="lptB"
                     /locus_tag="ROH59_001039"
     CDS             65777..66502
                     /gene="lptB"
                     /locus_tag="ROH59_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HDX4803557.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            66550..67983
                     /gene="rpoN"
                     /locus_tag="ROH59_001040"
     CDS             66550..67983
                     /gene="rpoN"
                     /locus_tag="ROH59_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDX4803558.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVPLED
                     ILESMGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            68006..68293
                     /gene="hpf"
                     /locus_tag="ROH59_001041"
     CDS             68006..68293
                     /gene="hpf"
                     /locus_tag="ROH59_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HDX4803559.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            68411..68902
                     /gene="ptsN"
                     /locus_tag="ROH59_001042"
     CDS             68411..68902
                     /gene="ptsN"
                     /locus_tag="ROH59_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HDX4803560.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LAPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            68948..69802
                     /gene="rapZ"
                     /locus_tag="ROH59_001043"
     CDS             68948..69802
                     /gene="rapZ"
                     /locus_tag="ROH59_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDX4803561.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            69799..70071
                     /gene="npr"
                     /locus_tag="ROH59_001044"
     CDS             69799..70071
                     /gene="npr"
                     /locus_tag="ROH59_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HDX4803562.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            70284..70916
                     /gene="yrbL"
                     /locus_tag="ROH59_001045"
     CDS             70284..70916
                     /gene="yrbL"
                     /locus_tag="ROH59_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HDX4803563.1"
                     /translation="MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALTSREA"
     gene            complement(70913..71641)
                     /gene="mtgA"
                     /locus_tag="ROH59_001046"
     CDS             complement(70913..71641)
                     /gene="mtgA"
                     /locus_tag="ROH59_001046"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HDX4803564.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAIFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEQA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRS
                     RQAWILRQMYQLGGEPFMQQHQLD"
     gene            complement(71638..72291)
                     /gene="elbB"
                     /locus_tag="ROH59_001047"
     CDS             complement(71638..72291)
                     /gene="elbB"
                     /locus_tag="ROH59_001047"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HDX4803565.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFASLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAILPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
BASE COUNT        17790 a        19351 c        17999 g        17213 t
ORIGIN      
        1 ttatggggaa ggtgttattt atgagtttta tttatgccgt tacgacaatg aactcgggaa
       61 ttagtataag cagcgcgaga ataataatca ttgtgcaaat gctaatttaa ttagtactat
      121 ttaaatatta ttttgagcat atgcacataa ggttgcgcgc taaagcacag atttgcgctt
      181 taccttgccg ggaggtactg caatccctga aatgattgac attgatcaca tttctgcatt
      241 taaactcctg acattcttat ttcacccaat gaagttattt atttttaaat gagaccaggt
      301 cctcatttta atagtccctg gctggagaat attgcacaat ggccaacatc gaaatcagac
      361 aagaaacgcc aactgcgttt tatataaaag ttcacgacac agataatgtg gcaattattg
      421 ttaatgataa tggcctgaaa gcaggaacgc gttttccgga tgggctggaa ttaattgaac
      481 atattcccca ggggcataaa gtcgcattgc tggacattcc ggctaatggt gaaattattc
      541 gttatggcga ggtgattggt tacgccgtgc gcgcaatccc acgcggaagc tggatcgacg
      601 aatcaatggt tgtactaccg gaagcgccgc cgttacatac gctgccactg gcaaccaaag
      661 tcccggaacc cttaccgccg ctggaaggat acacctttga gggctatcgc aatgccgatg
      721 gcagcgtggg caccaaaaac ctgctcggca tcaccaccag cgtccactgt gtggcaggcg
      781 tggtggacta cgtagtaaaa atcattgaac gcgatctgct accgaaatac ccgaacgtcg
      841 atggcgtggt ggggctgaat catttgtacg gttgtggcgt ggcgattaac gcacccgcgg
      901 cagttgtacc tattcgtacc attcacaata tttcgctgaa ccctaacttt ggcggcgaag
      961 taatggtgat tggtctgggt tgtgaaaagt tgcagcctga acgcctactg actggaacgg
     1021 atgatgtgca agctattcca gtagaaagcg ccagcattgt cagtttgcag gatgaaaagc
     1081 atgtcggttt tcagtccatg gtcgaggata ttttgcaggt agccgaacgc catctacaaa
     1141 aactgaatca acgtcagcga gaaacctgtc cggcttcaga actggttgtc ggcatgcagt
     1201 gcggtggcag cgatgcgttt tctggcgtaa cggcaaaccc ggcggttggg tatgcgtctg
     1261 atctattggt gcgctgcggc gcaacggtga tgttttcaga agtcacagaa gtgcgtgacg
     1321 cgatccatct gctgacacca cgcgcagtga acgaagaggt cggcaaacgg ctgctggagg
     1381 agatggagtg gtacgataac tatctcaata tgggaaaaac cgaccgcagc gccaaccctt
     1441 cgccgggcaa caagaaaggc ggtctggcaa acgtggtaga gaaggcactc ggctccattg
     1501 ctaaatcggg taaaagtgca attgttgaag tgctgtcgcc cggccaacgc ccgactaaac
     1561 gcggattaat ttacgccgcg acgccagcca gcgattttgt ctgtggcacg caacaggtgg
     1621 cttcgggtat caccgtgcaa gtgtttacga ccggtcgtgg tacgccgtac ggccttatgg
     1681 cggtacccgt cattaaaatg gcgacccgca ccgagctggc gaaccgctgg tttgatttaa
     1741 tggatattaa cgcgggcact atcgctaccg gcgaagaaac cattgaagaa gtgggctgga
     1801 agttgttcca ctttattctc gacgtcgcca gcgggaagaa gaaaactttc tcggatcaat
     1861 ggggactgca taaccagctg gcggtgttta acccggcacc ggtgacctga tttcttttgg
     1921 aacgtccctc gcaaaacatg gccttagtgc catgttttta ttgtttaaag tccacacatc
     1981 cattaataat gcatttgcat taccttagtt caagcttata atttgagcag aaaacaggct
     2041 gtaaaaggac agtaaataat gcccgctaat gctcgctcta acgctgtact gaccactgaa
     2101 tcaaaggtca ctatacgcgg acaaacaact atccccgcgc cagtgcgtga ggccttaaaa
     2161 ctgaagccag gcctggacag cattcattac gaaattctgc ctggtgggca agtatttatg
     2221 tgccgactgg gagatgaaca ggaggatcat actatgaatg catttttgcg ttttctggat
     2281 gcagatatcc agaacaatcc gcaaaaaact cgtccattcg acattcaaca aggaaagaaa
     2341 cttgtcgctg gcatggacgt caacattgac gatgagattg gcgacgacga ataatggatt
     2401 ttccacaaag ggttaatggt tgggcgctat atgctcatcc ctgttttcag gaaacctacg
     2461 atgctttagt tgccgaagtc gaggcattaa agggaaaaga tcctgaaaat tatcagagaa
     2521 aagctgccac aaagttattg gcggtggtcc ataaagtgat tgaggagcat atcacggtca
     2581 atccatcatc accggcattc cgtcatggca agtcgttagg ctctgggaaa aataaagact
     2641 ggtcacgggt aaaatttggt gctggtcgct atcgtctctt ctttcgttac agtgaaaaag
     2701 agaaagtcat cattctggga tggatgaacg atgaaaacac gctgcgcacc tacggtaaaa
     2761 aaacagatgc ctataccgta ttcagtaaaa tgttaaaaag aggacatcct cctgccgact
     2821 gggaaagcct cacccaagag acagaagaaa accattgatg gtgttcacaa tgcccgccga
     2881 acgcattggt gttgaccagc gggcatcctt tctcattccc cgaccagaat cacttcaacc
     2941 ccagcctttc gcagtccttc cagactatcc gcaggaatgc cttcatcaac aatgatcatg
     3001 tcgatacgtt gagtatcaat gatcttatgt aaactggaac ggttgaactt actggaatcg
     3061 gtgaccacga tgatccgttc cgcaacttcg cacatccgac ggtttaaacg ggcttcatct
     3121 tcattatgcg tgctgacgcc acgctccaga tcgatcgcat ctacaccaag aaacagcata
     3181 tcgaagtggt aattttgcag cgattgctca gcctgatcac cgtaaaaaga ttgcgactga
     3241 cggcgcaaat gccccccggt catcagcagc tcaacgcctt ccgcttccag caacgcatta
     3301 gccacgttca taccgttggt catcgcaatt acgtcggtgt gcttgcgcat cagacgagca
     3361 atctcaaaag tggtggtccc ggagtcgagg atcacccgat gaccaggctg aatcaactca
     3421 acggcagctt tcgcaacgct gcgtttcatc gcggtgttca gtgcgctttt atcttccact
     3481 gatggctcga ctgacggcgt tgtgctatcg cagatcaacg cgccaccata ggcacgcacg
     3541 gcgatcccct gcttttccag aaacgccaga tcgttgcgga tcgtcacagt agatacgcca
     3601 tacaatgccg acagatcgtt aacctgcaca ctcccttgct gtcgcagacg ctgaatgatc
     3661 tgttctcgtc gctcgctggt gcctgtcact cgcttctcac ctgaagcgtc ggtattactc
     3721 atagtaagtc ctttcgtaaa actttcgttt catttcgttt tgcctattaa cgcctttcta
     3781 ttaagcaaat gcaagcccac cttacccatt ggcgcaagct actctcgttt cagtggcttt
     3841 cattatgttt cttttgtgaa tcagatcaga aaactattat ctttcgtttt atttttatct
     3901 caccatgacg cagtatcaac tgaaacaaaa cgaaagatta atgtcgcagt aatctgaact
     3961 ggagaggaaa gtgaaacatc tgacagaaat ggtgagacag cacaaagcgg gcaaaacaaa
     4021 tgggatttat gccgtttgtt ccgcacatcc gctggtgctg gaagctgcaa tccgctacgc
     4081 cagtgcaaac caaacgccgt tactgattga agctacctcc aatcaggtgg accagtttgg
     4141 cggttatacc ggaatgacgc ccgccggttt tcgcggcttt gtttgtcagc tcgccgactc
     4201 gttgaatttc ccgcaggatg cgctgattct gggtggcgac catctggggc caaaccgctg
     4261 gcaaaatctg cctgccgctc aggcaatggc caatgccgat gatttgatta aaagctacgt
     4321 ggcggcagga ttcaaaaaaa ttcaccttga ttgcagcatg tcctgtcagg acgatccgat
     4381 tcccttaacc gatggcatcg tggccgaacg cgccgctcgt ttggcgaaag tggcggaaga
     4441 aacctgccgt gaacattttg gcgaagccga tctggagtat gtcattggta ccgaagtgcc
     4501 ggtgcctggc ggcgcgcatg aaaccttaag cgagctggcg gtcaccacgc cggatgccgc
     4561 ccgcgccacg ctggaagccc atcgtcacgc ttttgaaaag cagggtctga atgccatctg
     4621 gccacgcatc attgccctgg tggttcaacc cggcgtcgaa ttcgatcaca ccaacgttat
     4681 tgattatcag cccgccaaag cgaccgcctt aagccagatg gtcgaaaact acgaaacgct
     4741 gattttcgaa gcgcactcta ccgattatca aacgccgcaa tcgctgcgcc agctggtgat
     4801 tgaccacttt gccattctga aagttggccc ggcgctgacc tttgctctgc gtgaagctct
     4861 gttctctctg gcagcgattg aagaagaact agtgccagca aaagcctgtt ctggtctgcg
     4921 tcaggtgctg gaaaacgtga tgctcgaccg cccggaatac tggcaaagcc actaccacgg
     4981 tgacggcaac gcgcgtcgtc tggcgcgtgg ttatagctac tcggatcgcg tgcgctatta
     5041 ctggccggac agccagattg atgacgcttt cgctcatctg gttcgtaatc tggcggattc
     5101 accaattccg ctgccgctga tcagtcagta tctgccgctg cagtacgtga aagttcgctc
     5161 cggcgagctg cagccaacgc cacgggaact cattatcaac catattcagg acatcctggc
     5221 gcagtaccac acagcctgtg aaggccaata agcaaaacaa agaggaacac gctatgccaa
     5281 atattgtttt aagtcggatt gatgaacgct tgattcacgg tcaggtcggc gttcagtggg
     5341 taggatttgc gggggcaaat ctggtgctgg tagccaacga tgaggttgcc gaagatccgg
     5401 tacaacaaaa cctgatggaa atggtactgg cagaagggat cgccgtacgt ttctggacgc
     5461 tgcaaaaagt catcgacaac atccatcgcg ccgccgatcg acagaaaatc ctgctggttt
     5521 gtaaaacacc ggccgatttc ctgacgctgg tgaaaggtgg cgttccggtg aatcgcatta
     5581 acgttggcaa tatgcactac gccaatggca agcaacaaat cgccaaaacg gtttctgtgg
     5641 atgcgggtga tatcgcagca tttaacgacc tgaaagccgc tggggtggaa tgcttcgttc
     5701 agggcgtccc gacagagcct gctgtggacc tctttaaatt actttgaggg attcatcatg
     5761 gaaatcagtc tgttgcaggc atttgcgttg ggcattatcg cctttatcgc tggcctggat
     5821 atgtttaacg gcttaaccca tatgcaccgc ccggtggttc tcggcccgtt ggtcgggctg
     5881 gtacttggcg atctgcatac cggtatttta accggcggta cgctggaact ggtgtggatg
     5941 gggctggccc cgctggcggg cgcacagccg cctaacgtga ttatcggtac tatcgtcggc
     6001 acggcgtttg ccattactac tggcgtgaaa cccgatgtcg cggtcggtgt cgccgtacct
     6061 ttcgctgttg cagtacagat ggggattacc ttcctgttct cggtgatgtc cggcgtgatg
     6121 tcccgctgcg accggatggc ggagaacgcc gatactcgcg gcattgaacg cgtgaactat
     6181 ctggcactgc tggcactcgg cactttctat tttctctgcg ctttcctgcc tatctacttc
     6241 ggcgcggaac atgcaaaaac catcattgat gtcctgccgc aacgattaat tgatggcctc
     6301 ggcgtcgcgg gcggcatcat gccagcaatc ggttttgccg tgctgctgaa aatcatgatg
     6361 aaaaacgtct acatccccta cttcatcctg ggctttgttg ccgcagcctg gctcaagtta
     6421 ccggtgctgg ctattgctgc cgctgcgctg gcgatggcgc tgatcgacct gctgcgtaaa
     6481 tctcctgaac cgactcaacc tgcggcacag aaagaggaat ttgaagatgg catctaatca
     6541 aaccaccctg ccgaacgtca gcgaaaatga agaaacactg ctgactggcg tcaatgaaaa
     6601 cgtgtatgaa gatcagagca ttggcgcaga gctgacgaaa aaagatatca accgcgtcgc
     6661 ctggcgctcc atgctgttac aagcgtcttt caactacgaa cgtatgcagg cttccggctg
     6721 gttgtacggt ctgctgcctg ctctgaaaaa gatccacact aataaacggg acctggcgcg
     6781 cgccatgaag gggcatatgg gtttcttcaa tacccatccg tttctggtga cgtttgttat
     6841 cggcattatc cttgcgatgg agcgttctaa gcaggacgtt aacagtattc agagcaccaa
     6901 aattgccgtc ggtgcgccgc tcggcgggat tggcgatgcg atgttctggc taacgctact
     6961 gccgatttgt ggcgggatag gcgcaagcct cgcgctacaa ggctctattc ttggcgctgt
     7021 cgtctttatt gtgctgttca acgtggtgca cctggggctg cgttttggtc tggcgcatta
     7081 tgcttaccgc atgggcgtgg cggctattcc actcattaaa gcaaatacca aaaaagtcgg
     7141 ccatgcggcg tctatcgttg ggatgacggt gatcggcgcg ctggtggcaa cctatgttcg
     7201 tttaagcacc acgctggaaa tcacggcggg cgacgcagtg gttaagttac aggctgatgt
     7261 tatcgacaaa ctgatgcctg ccttcttacc gctggtctac accctgacca tgttctggct
     7321 ggtacgccgc ggctggagtc cgctgcgcct gattgcagtg acagtggttc tcggcatcgt
     7381 cggtaaattc tgccatttcc tttaaataca atgaggtatt agatgttaag tattattttg
     7441 acagggcatg gcggatttgc cagcggcatg gaaaaagcaa tgaagcaaat cctcggcgag
     7501 caatcgcagt ttatcgccat cgattttcca gaaacctcaa gcaccgcgct gcttacatcg
     7561 cagcttgaag aggccatcgc ccaactggat tgtgaagacg gcattgtttt tctgacggat
     7621 ttgctgggcg gcacgccgtt tcgcgtagct tcaacgctgg cgatgcaaaa accgggctgt
     7681 gaagtgatca ccggcacaaa tttgcaacta ttactggaaa tggtgctgga acgcgaaggg
     7741 ttaagcggtg aagagttccg tgtgcaggcg ctggagtgtg gacaccgtgg gctaaccagt
     7801 ctggtggacg aacttggtcg ctgccatgag gaatgtccgg tcgaggaagg aatatgacac
     7861 acgttctgcg cgccagaagg ctgctgactg aagagggatg gctcgatgac catcagttgc
     7921 gtattgctga cggtgtaatc gcagcaatcg aaccgattcc agtgggcgtg actgaacgcg
     7981 atgcggaact gctctgcccc gcttacatcg acacccatgt acacggtggt gcgggcgttg
     8041 atgtaatgga tgacgcgccg gatgcgctcg acaagctggc aatgcacaag gcacgcgaag
     8101 gtgtcggcag ttggttaccg accaccgtaa ccgcgccgct taataccatt catgcggcgc
     8161 tgaaacgtat tgctctacgc tgccagcgcg gtgggcctgg tgcgcaagtg ctggggagtt
     8221 atctcgaagg accgtacttc acgccgcaga ataaaggcgc acatccgccg gagctgtttc
     8281 gcgagctgga aattgccgag ctggatcaat tgattgccgt ttctcagcag accttacgcg
     8341 tggtagcgct ggcaccagaa aaagaagggg cattgcaggc catccgccat cttaaacagc
     8401 aaaacgtacg ggtgatgctg gggcatagcg cggcgacctg gcaacaaacc cgtgccgcgt
     8461 ttgatgctgg tgccgacggc ctggtgcatt gctataacgg gatgacaggt ttacatcacc
     8521 gcgaaccggg aatggttggc gcgggattaa cggacaagcg cgcctggctg gaactgatag
     8581 ccgatggtca tcatgtacat ccggcggcaa tgtcgctctg ttgttgctgt gcgaaagaga
     8641 ggatcgtact gatcaccgac gcgatgcagg cagccgggat gccggatggt cactatacgt
     8701 tatgtggtga agaagtgcag atgcacggtg gcattgtccg taccgcgttc ggtgggctgg
     8761 cgggcagtac gctgtctgtc gatgcggcag tgcgcaacat ggtcgagttg acgggcgtaa
     8821 cgcctgcgga agccatccat atggcgtcgc tgcatccggc gcgaatgctg ggtgttgatg
     8881 gtgttctggg atcgcttaaa ccgggcaaac gcgccagcgt cgttgcgctg gatagcgggc
     8941 tgcatgtgca acaaatctgg attcagggtc aattagcttc gttttgatgg tttgctcctt
     9001 tattaggcct tcacttcccc cgtaaggcct ttctttttct ttctttttga tctgtgcagc
     9061 ggtgtcggat gcgacgctaa tgcgccttat ccgacctacg gttggtgacc gtaaggccgg
     9121 ataaagtatt tacgccgcat ccagcaatcc cttttacttc ccttgtcttt tctttcaacg
     9181 atcacagatt tcgttttatt tcctttttct ccattgaact ttcagtttct tttctataga
     9241 ttttaaccaa cgaaagaaat caccaagtga aatgaaacga aaggcaagcg aaagcgacaa
     9301 cgccgacgtc aagttcatca gactaaggat tgagttatgc cagaaaatta cacccctgct
     9361 gctgccgcaa ccggtacatg gactgaagaa gagatccgcc atcagcctcg cgcatggatc
     9421 cgttcactca ccaacattga cgcgctacgt tccgcgctca ataacttcct tgaaccgtta
     9481 ctgcgcaaag agaatctgca aatcatcctg accggagccg gaacatcggc atttatcggt
     9541 gacatcatcg cgccgtggct cgccagccat accggtaaaa acttcagcgc cgtaccaacc
     9601 accgatctgg tcaccaatcc aatggactac ctgaacccag ctcatccgct actgttgatc
     9661 tccttcggtc gctccggcaa cagcccggaa agcgtcgccg ccgtggaact ggcaaatcaa
     9721 tttgtaccag aatgctatca cctgccgatc acctgcaacg aagcgggcgc tctttaccaa
     9781 aacgcgatca acagcgacaa cgcgtttgcc ctgctgatgc ccgcagaaac gcacgatcgc
     9841 ggctttgcga tgaccagcag cattaccacc atgatggcca gctgcctcgc ggttttcgca
     9901 cctgagacga tcaacagcca aaccttccgc gacgtggcgg atcgttgcca ggcgatcctg
     9961 acctcactgg gcgatttcag cgaaggtgtg tttggttacg caccgtggaa acggatcgtt
    10021 tatctcggca gcggtggctt acagggcgca gcacgcgagt cggcgctgaa agtgctggaa
    10081 ctgacagcgg gtaaactggc ggccttctat gattccccga ccggattccg tcatggcccg
    10141 aaatcgctgg tcgatgacga aacgctggta gtggtgtttg tctccagtca cccttacacc
    10201 cgtcagtacg atcttgacct gctggcagaa ctccgccgtg acaaccaggc aatgcgcgtg
    10261 atcgccatca ccgctgaaag caacgacgtt atcgccgctg gcccgcatat catcctgccg
    10321 ccgtcccgtc actttatcga cgttgaacaa gcattttgct tcctgatgta cgcccagacg
    10381 tttgcactga tgcagtcgct gcacatgggc aatacgccgg ataccccatc agccagtggc
    10441 accgtaaacc gcgtggtgca aggcgtaact attcatccgt ggcaggcata agaggatcgc
    10501 attatgagca ttatctccac caaatatctg ttacaggacg cccaggccaa tggctacgcg
    10561 gtgcctgcct ttaacatcca taacgccgag acgatccagg cgatcctcga agtgtgcagt
    10621 gaaatgcgat cgccggtgat cctcgccggg acaccaggta cctttaagca tatcgcgctg
    10681 gaagagatct acgccctgtg tagcgcctat tccacgacct ataacatgcc gctggcactg
    10741 catctcgacc accacgaatc gctggatgat attcgccgta aagtccacgc aggcgtgcgc
    10801 agcgcgatga tcgacggcag ccacttcccg tttgccgaga acgtgaagct ggtgaaatcg
    10861 gttgtcgact tctgccactc ccgggattgc agcgtggaag cagaactggg ccgcctcggc
    10921 ggtgttgaag atgacatgag cgttgacgcc gaaagtgcat tcctgaccga tccacaagaa
    10981 gctaaacgct ttgtcgaact gactggcgtc gacagcctgg cggtagcgat tggtacggcg
    11041 cacggcttat acagcaaaac gccgaagatt gatttccagc ggctggcgga aattcgtgaa
    11101 gtggtggatg ttcctctggt gctgcatggt gccagcgatg tcccggatga atttgtccgt
    11161 cgcactattg aactcggtgt aacaaaagtg aacgttgcca cagaattaaa aatagccttc
    11221 gctggcgcgg ttaaagcctg gtttgcggaa aatccgcagg gtaatgatcc tcgttattat
    11281 atgcgcgtcg gaatggatgc gatgaaagaa gtggtcagaa ataaaattaa tgtctgtggt
    11341 tcagcgaatc gaatttcagc ataatcatta attttatacg ttttttcaga atgcactgcc
    11401 cgattaatat cgggtagtac cttaatggca aaggagataa ccaaacatta ataaatacat
    11461 cagtacaata tcgcaacaat aatatattta aaaatattat attattcaac tttatggtga
    11521 ggattacaca atgagcagtc caaatattct cttaacccgt attgataacc gtctggttca
    11581 cggtcaggtt ggcgtgacct ggacatccac catcggtgcg aatctgttgg tagtcgtgga
    11641 tgatgttgtc gctaacgatg atattcaaca gaaattaatg ggtattaccg cagaaaccta
    11701 cggctttggc attcgtttct ttactatcga aaaaaccatt aacgtcatcg gcaaagctgc
    11761 accacatcag aagatcttcc tgatttgccg tacgccacaa acggtacgta aattggtaga
    11821 aggtggtatt gacctgaaag atgtcaacgt cggcaatatg catttctcgg aagggaaaaa
    11881 gcaaatcagc agtaaagttt atgtcgatga ccaggatctc acggacttac gttatattaa
    11941 acaacgtggc gtgaatgttt tcattcagga cgttcctggc gatcaaaaag aacaaatccc
    12001 tgactaaatc tgaaatcgcc ttaatattgg tttgaggtaa taaaaatgca tgaaataacc
    12061 ctactccagg gattatccct ggcggcgtta gttttcgttc tggggattga tttttggctg
    12121 gaagccttat ttttattccg cccgataatc gtttgtaccc ttacaggtgc tattctcggt
    12181 gatattcaga ctggcttaat taccggaggc ctgacagagt tggctttcgc cggattaacc
    12241 cctgcaggtg gtgttcagcc gcccaaccct attatggcgg gtctgatgac caccgtcatt
    12301 gcatggtcta cgggcgttga tgccaaaacg gcaattggtc ttggcctgcc gtttagtttg
    12361 ttaatgcagt acgtcattct gttcttctat tccgctttct cattatttat gaccaaagcc
    12421 gataaatgcg cgaaagaggc ggatacggca gcgttttccc gacttaactg gacaacgatg
    12481 ctcatcgtcg cttcagcgta tgcggtgatt gctttcctct gtacttacct ggcacaaggg
    12541 gcgatgcagg cgctggtgaa agcgatgccc gcctggctga cccacggctt tgaagtggct
    12601 ggcggtattc tgcctgccgt tggttttggc ttgctgctgc gcgtgatgtt caaagcgcaa
    12661 tatatccctt acctgatcgc cggtttcctg tttgtttgct acatccaggt cagcaacctg
    12721 ttgccggttg ccgtgctggg cgcaggcttt gcggtgtatg agtttttcaa tgcgaaatcc
    12781 cggcagcaag cgcaaccgca gcccgttgcc agtaaaaatg aagaagagga ctacagcaat
    12841 gggatctgaa atcagtaaaa aagatatcac ccgtctgggc tttcgttcgt cactgctaca
    12901 agcaagcttt aactacgaaa ggatgcaggc gggcggtttt acctgggcga tgttgccgat
    12961 cctgaaaaag atttataaga acgacaaacc gggcctaagc gcggcgatga aagataacct
    13021 cgaatttatt aatacccacc ctaatctggt cggatttctg atggggttat taatttcgat
    13081 ggaagaaaaa ggagaaaacc gcgacaccat taaaggcctc aaagtggcac tgtttggccc
    13141 aatcgccggg attggcgatg cgattttctg gtttactttg ttgccgatta tggcggggat
    13201 ttgctcatcg tttgccagtc aggggaacct gttgggaccg attttgtttt tcgccgttta
    13261 cctgcttatc tttttcctgc gcgtcggctg gacccacgtc ggttattcag tcggcgtgaa
    13321 ggctattgat aaagtgcgag agaactcgca gatgattgcc cgttcggcaa ccatcctcgg
    13381 gatcacagta atcggcgggc tgatcgcttc gtatgtgcat attaacgtgg tgacatcgtt
    13441 tgccatcgac agtacccaca gcgtcgcgct gcagcaggat ttcttcgata aagtcttccc
    13501 gaatatttta ccgatggcct acaccctgct gatgtattac ttcctgcggg tgaaaaaagc
    13561 gcatccggtg ctgttaatcg gcgtgacgtt tgttctttct attgtttgtt ctgcattcgg
    13621 cattttgtaa atggaacgag gcaccgcgtc tggcggtgcc tctttactta aggaatttca
    13681 tcctgtgcaa acccttcaac aagttgaaaa ctatacggcg ttaagtgaac gtgccagcga
    13741 atatttattg gccgtgatcc gtagcaaacc ggatgccgtg atttgcctgg cgaccggagc
    13801 cacgccatta ctgacgtatc attatttggt agaaaaaatc caccagcagc aggttgatgt
    13861 cagccagctc accttcgtga agctcgacga atgggtggat ctgccattaa cgatgcctgg
    13921 tacctgcgaa actttccttc aacagcatat cgtgcagccg ctggggctac gtgaagacca
    13981 gctcatcagc tttcactccg aagagataaa tgagacagag tgcgaacggg taacgaacct
    14041 gattgcgcgc aaaggcggtc tggacttatg cgttctcgga ttggggaaaa acggtcatct
    14101 tgggctgaac gaaccgggag aaagcctgca accggcctgc catatcagtc aacttgatgc
    14161 cagaacacag caacatgaga tgttaaaaac cgctgaccgt cccgtgactc gtgggatcac
    14221 cttaggcctg aaggatattc tcaatgcccg cgaagttttg ttactgataa ctggcgaagg
    14281 aaaacaggat gcgacagaac gttttctcac ggctaaagtc tccaccgcta tcccggcttc
    14341 atttttatgg ctgcataacc atttcacatg cgtgattgat gaaatgtgtc gtcgttaact
    14401 cgcctggtac aggcgttgca gcgctattcc tgctgcgacg cctgtaatca ctctccctgc
    14461 tgctccagcg catacttata cagcgcattt ttcttcacgc cgtgaatttc tgcggccagc
    14521 gccgccgctt ttttcagcgg cagttctgcc tgtaacagcg ccagcgtgcg cagggcatca
    14581 gcaggcaggt catcttcctg cgctttatgg ccttcgacaa tcagcaccat ttcgcctttg
    14641 cgacggtttt catcttcttt tacccacgcc agcagctcgc caacgggcgc gccgtgaatg
    14701 gtttcccagg ttttggttag ctcacgcgcc agaaccacgt aacgggattc gcctaatacc
    14761 gcaacaatat cttccaggct atctaacaga cggtgggtag attcataaaa aatcagcgtg
    14821 cgcggctccg cttcaatagc ttttagcgca tcacggcggc cttttgattt ggcaggtaaa
    14881 aagccttcat aacaaaaacg atcggatggt aaacccgcgg cgcttaacgc agtgatagca
    14941 gcacacggcc ctggtagcgg caccacgcga atccccgctt cacgacaggt acgcaccaga
    15001 tggtagccag gatcgttaat tagcggcgtt ccggcatcgg aaaccagcgc aatgttttgc
    15061 ccctcttgca gcttcgccag cagcgtttcg gctttttgtt gttcgttatg atcgtgcagc
    15121 gcaaacaacc gggcattaat cccaaaatgt tgcagcaata aaccggtgtg acgcgtatcc
    15181 tcggcggcaa tcagatcaac ggcctgtaat acctctaatg cacgctgggt gatatccgcc
    15241 agattgccga ttggcgtcgg tacaatgtaa agctgcccct gagaattatc cgccgattgg
    15301 tgttgtttca ttgtgtcgtc cgtattgccg atttaatatt gagcattgcg taaaaaaaat
    15361 atcactggat acattatggt accctcaaca ttttctcgtt tgaaagccgc gcgttgtctg
    15421 cctgttgttt tggcagccct gattttcgcc ggttgtggca cccatactcc cgatcagtcc
    15481 actgcttata tgcagggcac ggcgcaggct gattctgctt tttacctgca acagatgcag
    15541 caaagttctg atgataccag gatcaactgg caattactcg ccattcgtgc actggtgaaa
    15601 gaaggtaaaa ccgggcaggc ggttgagttg gttaaccaac taccgcaaga actgaatgat
    15661 aatcagcgtc gcgagaaaac actgctggcg gcagagatta aactggcgca gaaagatttt
    15721 gctggcgcgc aaaacttgct ggcgaaaatc acacctgccg atttagaaca aaaccagcaa
    15781 gcccgttact ggcaggcaaa aatcgatgcc agccaggggc gtccttccat tgatttactg
    15841 cgcgcgttaa ttgctcagga accgctgctc ggtgcgaaag aaaagcagca gaatattgac
    15901 gccacatggc aggcgctctc ctccatgact caggagcagg cgaatacgct ggtgatcaac
    15961 gccgacgaaa atattctgca aggctggctg gatttgcagc gcgtctggtt tgataaccgt
    16021 aacgatcctg acatgatgaa agctgggatc gccgactggc agaaacgtta tccgaacaac
    16081 ccgggcgcga aaatgctgcc aacgcagttg gttaacgtaa aagcgtttaa accagcatcg
    16141 accaacaaaa tcgccctgct gttgccgctg aatggccagg cagcggtatt tggtcgcact
    16201 attcagcaag gctttgaagc ggcgaaaaat atcggcactc agccagtggc ggcccaggta
    16261 gctgccgcac ctgccgcaga cgtagcagaa caacctcagc cgcaaaccgt ggatggcgtt
    16321 gccagcccgg cacaagcttc ggttagcgat ctgaccggtg aacagcctgc ggcccagccg
    16381 gtacctgtaa gcgccccggc gacaagcacc gcagcggtaa acgcacccgc aaatccatcc
    16441 gcagagctga aaatctacga tacctcatca caaccactta gccagatctt aagccaggtt
    16501 cagcaggatg gtgcgagtat tgtggtcggt ccgttgctga aaaataacgt tgaagagttg
    16561 ctgaagagca acaccccgct gaacgtgctg gcactgaacc agccggagaa tatcgaaaac
    16621 cgcgtcaata tttgttactt cgcgctttcg ccagaagacg aagcgcgcga tgcagcgcgt
    16681 catattcgtg accagggtaa acaagcgccg ctggtgctga tcccgcgcag ttcattgggc
    16741 gatcgcgtag ccaatgcgtt tgcgcaagag tggcagaaac tgggtggcgg caccgttctg
    16801 caacaaaaat ttggttccac cagcgaatta cgcgcgggtg ttaacggcgg ttctggtatt
    16861 gctttaacgg gtagcccgat tactcccaga gcgacaaccg actccggcat gacgaccaac
    16921 aatccaacgc tgcaaaccac gccaaccgat gaccagttca ccaataatgg cggtcgtgtc
    16981 gatgcggtgt acattgtggc aacgccgggt gaaatcgctt ttatcaaacc gatgatcgcc
    17041 atgcgtaacg gtagccagag cggtgcaacg ctgtacgcca gttcccgcag tgcgcaaggg
    17101 accgctggcc cggatttccg cctggagatg gaaggcttgc agtacagcga aatcccgatg
    17161 ctggcaggcg gtaatctgcc gttaatgcag caggcgctca gcgcggtgaa caacgattat
    17221 tcgctggctc gcatgtatgc gatgggtgtc gatgcctggt cgttggcaaa tcatttctca
    17281 caaatgcgcc aggttcaggg ttttgaaatc aacggtaata ccggaagcct gacggcaagc
    17341 ccggattgcg tgattaacag gaagttatca tggctacagt accaacaagg tcaggtagtc
    17401 cccgccagtt aaccaccaaa cagaccggcg atgcgtggga agcacaagcg cgtcgctggc
    17461 tggaaggcaa aggactacgg tttatcgccg ctaacgtgaa cgagcgtggc ggcgagatcg
    17521 atctgataat gcgtgaaggc cggaccaccg tttttatcga ggtgcgttac cgccgctctg
    17581 cgctttatgg cggcgcggca gccagtgtga cccgcagcaa acaacacaaa ttattacaga
    17641 ctgcccgttt gtggctcgcg cgtcataatg ggagttttga tactgtggat tgccggttcg
    17701 atgtggtagc cttcaccggg aatgaggttg agtggattaa ggatgccttt aatgaccact
    17761 cataattaag gtttaaggat tagcgtgcaa gaaagaatta aagcttgctt cactgaaagc
    17821 attcaaactc aaattgcggc ggcagaggcg cttccggatg ccatctcccg tgcagccatg
    17881 acgctggttc agtctctgct caatggcaac aaaatcctct gttgtggtaa tggaacttcc
    17941 gctgccaatg cacagcattt tgctgccagc atgatcaacc gtttcgaaac ggagcggccc
    18001 agcttacctg ccattgcact aaatactgat aatgttgtct taacggcaat tgccaacgat
    18061 cgcttacatg atgaagtgta tgcaaaacag gtgcgggcgc tgggtcatgc gggagatgta
    18121 ttgttagcca tttccacccg tggcaacagc cgcgatattg taaaagcggt agaagctgcc
    18181 gttacgcgtg atatgaccat tgtggcatta accggctatg acggcggtga acttgcaggt
    18241 ttgttagggc cacaggatgt ggagatccgc attccttcgc atcgtagtgc tcgcattcag
    18301 gaaatgcata tgctgacggt aaattgcctg tgcgatctga tcgataacac gcttttccct
    18361 caccaggatg tttaaggaga atacatgaag gcattatcgc caatcgcagt ccttatttcc
    18421 gcgctgctgt tgcaaggttg tgttgccgct gccgtagtgg gtactgctgc tgtgggtacc
    18481 aaagccgcaa ctgacccacg cagtgtcggc acccaggtag acgatggtac cttggaagtg
    18541 cgcgtgaaca gcgcattgtc gaaagacgaa caaattaaga aagaagcgcg cattaatgta
    18601 acggcctatc agggcaaagt gctgctggtt gggcagtcac caaacgctga actttcggct
    18661 cgcgccaaac agattgctat gggcgtagac ggtgccaacg aagtgtataa cgagattcgt
    18721 cagggccagc cgattggtct gggcgaagcg tctaacgata cgtggatcac caccaaagta
    18781 cgttcgcagc tgttaaccag cgacctggtg aaatcgtcca acgtgaaagt gaccaccgaa
    18841 aacggtgaag tgttcctgat ggggctggtg actgaacgtg aagcgaaagc ggcggcagat
    18901 attgccagcc gggtaagcgg cgtgaagcgg gtaactacgg cgtttacgtt tattaaatag
    18961 cagcccttgt aatgcctgat gcgacgcttg cagcgtctta tcaggcctac aacgatgcaa
    19021 accgtaggtc ggataaggcg tttacgccgc atccgacatg ttttccctca aatcaaacta
    19081 acagcgccag cccgccgaca atcacaccag acactgccac catcgccccc gtcagccata
    19141 aggctttcgc cgggaacgct ttgcgcagca taatcagtga cggcaaactc accgccggga
    19201 gcgtcatcaa caatgccagc gccggagcag ttcccatacc tgccagcatc atcgtttgta
    19261 caatcggaat ttctgctgcc gtgggaatga caaacaagca tcctgccacc gccatcgcca
    19321 ccacccacat caggctgtta tcgacagcac catcggcatg ggggaataac cagacgcgag
    19381 cggcacccaa caccagtact gcaaggatgt aaaccgggat cgtactccag aaaagcgtcc
    19441 atagcgccct gccccagcgg ctaaaaaatc ctccctgtgc ttccggtata tcaatttcga
    19501 ccggtgcctg cgtttgcggt gtttcacgca cccatttttg caccagcgtc gcaatcagca
    19561 acaccatcac cagccccgcc accagacgaa tcgccgcaaa accccagccg aggacgaacc
    19621 ccataaacac cagcgtcgcc gggtttaaca acggattccc catccagaat gccagcgcac
    19681 cgcccatcga cacctgttgg cgacgcattc ccgccgcgac cggagccgca cagcaggtac
    19741 acatcatacc cggcagcgaa aacagcgttc ccagcagcgt gccgcgaaag cgcgattgcc
    19801 caagcgtacg caacaaccag tcacgcggga tcagtacctg aatcaacgaa ccgaggatca
    19861 cccccagcac cgccgctttc cataccgcga ggaaatagat catcgcgtaa tccaacgccg
    19921 cctgccacgg attagcatcc gcctgcgcaa ggatagattt accgatactg tgggtttcgg
    19981 cagcagtaaa cgctttgccg tagtaaggtt gccatttcac ataccagaga ccggcaatga
    20041 caacgagaaa gaaaagcgcg ggtttccacc actgaatggg cgttgccgcc tgagatgaag
    20101 actgaccagt catagcattc cccaggaata agttatgata attgagcgcg tgaatattac
    20161 gctcactatc aattcttggg aataattatt cagctctttt gcgtaattct gaagagctta
    20221 aaatcgtcac accttcatgc tcaggccgca tcgcctctgc cagcatgacc cgcgccacgt
    20281 ctctcgcatc aatggatttc cagttaccgg gtaacaaacg gaacagcggc gcaaaaagcg
    20341 tttcgttcat ccgctgtttg ctacgatcac ccagtaacat cgacgggcga gcaatggtca
    20401 atttcggcca gttctgggcg attaatgctt cttccatctc ccctttgacg cggttataga
    20461 aaaacggcga gtgggcatta gcacccatag cactgaccac cagcatatgc tgcgcaccga
    20521 gccgccgccc ggttaatgcg gtatccacca ccaacgtgta atcggcatga ataaacgcct
    20581 ctttgctccc cgcttctcgc cgcgtggtgc cgagacaaca aaacacaatg tcgatgggat
    20641 cggtgacctg cgccagcgcg tcagtcagtt gcggatcatg gggattaaac accccgggca
    20701 tatcgcccaa cggacgtcgc gtcggcgcag caatgacgtt aactttcggt tcattaatca
    20761 acatccgcag caggtgaccg cccaccagcc ccgttgcgcc tgtaatcagt acctgactca
    20821 tcttcgctcc tttacagaat tgtctgcctt gcgctcccca gctcatgcac caggcttaat
    20881 agaccatgag gtaattatcc ccgattgtgg aaaattcgcc tcatccaatg caacaacgcg
    20941 gaggaagcat gagtaagaaa atcgccgctt taatcactga tgaatttgag gattcagaat
    21001 tcacttcacc cgcagacgag ttccgtaaag ccggacacga agtgattacc attgaaaaac
    21061 aagcgggtaa aacggtgaaa ggcaaaaaag gagaagccag cgtggtcatc gataaatcca
    21121 tcgatgaagt gacgcccgca gagttcgatg ccctgctgct accgggcggt cattcaccag
    21181 attatctgcg tggcgacaac cgttttgtca ccttcactcg cgattttgtg aacagcggca
    21241 aacctgtttt cgccatctgt cacggtcccc agttgctgat cagcgccgat gtgatccgtg
    21301 gtcgtaagct gaccgccgtt aaaccgatcg tgattgatgt taaaaacgcg ggcgcggaat
    21361 tttacgatca ggaagtggtg gtcgataaag atcagctggt taccagccgg acaccggacg
    21421 atctgccagc gtttaaccgc gaggcgttac gcctgctcgg tgcctgagtt acgtagccaa
    21481 atcatttttt taccaaagcc cagcgtgttg tcggtgaatt tgatttcatc gagccggatt
    21541 tcccataccg gggccgacag cattctggca accggaaagc gacgattgta cgccttgcgt
    21601 gcgaggtcgc tttcctcgcc ttccagtctg cggatctcac ctttaaactg cacgccgcga
    21661 attaacgcta ccgttttcgg ctgaccgttt accgttccgg caattgccgc ctgcggcccg
    21721 ctcatctgcg catgacgcgt tttttcttcc gtcaaaatgt agaaggcgac tttctgcgca
    21781 tcaaaaagat aaaaggcatt ggcgcaccac agttcccctt cctgctgcac acaccaggtg
    21841 acaacatgtt gttttgccag ccaacggctg atggcggtga gtgtttccat tgctgttctc
    21901 ttttatactg tgggcctgac cttaacatgc gacgcagacg atgacaccct ggtttcttta
    21961 cttgatccgt accgccgaca ataagcttta taccgggatc accacggatg tcgaacgccg
    22021 ctatcagcag caccaaagcg gcaaaggggc gaaagcactg cgagggaaag gagaactaac
    22081 gctggcgttt tccgcgccag tgggcgaccg ttcgctggca ctacgagcgg aatatcgcgt
    22141 taaacaactg actaaacggc aaaaagagcg tctggtaacg gaaggcgcag ggtttgcaga
    22201 actgttgagc agcctgcaaa ccccggagat taaaagcgat tgaaatgctc gtgatactcg
    22261 accagaccag ttacgccgtt cagcgcgtca tccgctaaac gatgtacctg gaaggcgctt
    22321 tcagtgcccg gccagcggca atgcagatcg tgatgcgccg ccagttcaaa gccgaaacgg
    22381 ctgtacagcg ccggatcgcc cagcgtcacc actgcggcat agccgaactc attaagcgaa
    22441 tcgagtcctt catagaccag ttggcgtgcc agcccctgtc cacggtattt ttcatcaacc
    22501 gccagcggtg ccatgccgac ccattgcagg tcttcgccct gcacatcaac cggactaaaa
    22561 gccacatagc caatgacctg accttcgtca tctgtcgcca ccagccccag cgtcagaaag
    22621 ccatcttcac gcagatcgtg aaccagcttc gcttccgcat cactttcgaa tgaacgacgc
    22681 agcagggcat caatacccgg cgcatcaatg ggaatttcta ctcgaattag catggttcac
    22741 ctaccgatgt ctgtttggtt tcaggcgcgg ttttcattcc cgcctcaaca aaatccgcca
    22801 gttgcagcag catcatgcgt aaggctttcg gcatttgctc cagttcaatg gcgtccatca
    22861 ggtttttcac atacagcccc agctccgtat cgccttcaat caccagccga cgctggaaga
    22921 agagcgtatc cggatcttgt ttacgcgccg caatcatcag cagatcgctg gcgtcggcac
    22981 taaaactcac atcagcttgc gcgttctggc taacgaccag tttgccattc accaccgagg
    23041 taaaccattg caggtcaata tcacgcacat gaatacttaa ccagcgacct tcaagaaact
    23101 ccagctcgcc atcatccagc gcctgacgga attgccagct taagacctgc tcaagaacct
    23161 ggcgttttag cgcaaatggc gtcagtttta ccggtacact caacagagat ggccccaaat
    23221 gcacaatacg ggaacgcagt ttatccaaca cgagttttac tccctgtttc aacaatcatc
    23281 ctattttgcc atatcagaaa aataacatag cggtataaat caacaattcc atatgaaatt
    23341 gctgctacca ccaatacaac tttaactgcc ttaaatcaaa aattgtcgca gcaaggttaa
    23401 ctaaaatccc agttcgttaa catttttgcg ttttgatagc gcaaccttca ggaaaaatta
    23461 tggagctgct ctgccctgcc ggaaatctcc cggcgcttaa ggcggccatc gaaaacggcg
    23521 cagatgctgt ttatatcggg ctaaaagatg ataccaatgc ccgtcacttc gccggcctta
    23581 actttaccga gaaaaaattg caggaagcgg tgagttttgt ccatcaacat cgccgcaaac
    23641 ttcacatcgc gattaacact tttgcgcatc cggacggtta cgcccgttgg cagcacgccg
    23701 tggatatggc ggcgcaactg ggtgccgacg cgctgatcct cgccgacctc gccatgctgg
    23761 agtacgccgc cgaacgttat ccgcatattg agcgccacgt atcggtgcag gcttcggcga
    23821 ccaatgaaga ggcgattaac ttttatcatc gccattttga cgttgcccgc gtggtactgc
    23881 cgcgcgtgtt gtcgattcat caggtgaaac agctggcacg ggtcacacct gtaccactgg
    23941 aagtgtttgc tttcggcagc ctgtgcatta tgtcggaagg ccgttgctat ctgtcgtcgt
    24001 atctgacggg tgaatcgccc aacaccgtgg gggcatgttc tccggcccgt ttcgtgcgct
    24061 ggcagcaaac gccgcaaggg ctggaatccc gcctgaacga agtgctgatc gaccgttatc
    24121 aggacggcga aaacgcaggt tatccgacgc tgtgtaaagg gcgttatctg gtggacggcg
    24181 agcgctatca cgcgctggaa gaaccaacca gtctcaatac cctggaactg ctgccggagt
    24241 taatggcggc gaatattgct tcggtgaaaa ttgaaggccg ccagcgtagc ccggcgtatg
    24301 tcagccaggt ggcgaaagtc tggcgtcagg ctatcgaccg ttgtaaggcc gatccgcaaa
    24361 acttcgtacc gcaaagcgcg tggatggaga cgctcgggtc gatgtccgaa ggcacgcaaa
    24421 ctacccttgg cgcgtatcac cgtaaatggc agtgagaaaa gcaatgaaat attccttagg
    24481 gccggtgcta tggtactggc caaaagagac gctggaagac ttttatcagc aggccgccgc
    24541 cagcagcgca gacgtgattt atcttggtga agcggtatgc agcaagcgcc gggcaaccaa
    24601 agttggcgac tggctggaga tggcaaaatc actcgccgga agtggtaagc agattgtgct
    24661 ctccacgctg gcgctggtgc aggcatcctc tgaactgggc gaactgaaac gctatgttga
    24721 gaacggtgag tttctgattg aagccagcga tctcggcgtg gtgaatatgt gcgctgaacg
    24781 caaactgccg ttcgtcgccg ggcacgcgct gaactgctac aacgcggtga cgctgaaaat
    24841 attgcttaaa cagggcatga tgcgctggtg tatgccggtg gagctttccc gcgactggct
    24901 ggtgaatctg cttaatcagt gcgatgagtt gggcattcgc aaccagtttg aagtggaagt
    24961 cctgagctac ggtcatctac cgctggccta ctccgcacgc tgctttaccg cgcgttcgga
    25021 agaccgcccg aaagatgagt gtgaaacctg ctgcattaag tatccgaacg ggcgcaacgt
    25081 actgtcgcag gaaaaccaac aagtgtttgt actcaacggc attcagacca tgagcggcta
    25141 cgtttacaac ctcggtaacg agctggcatc catgcagggg ctggtcgatg tggtccgcct
    25201 gtcaccgcag ggtactgaca ctttcgcaat gctcgatgcc ttccgcgcta atgaaaatgg
    25261 cgctgcgcca ctaccgttga cggcaaacag cgactgtaac ggctactggc ggcggctggc
    25321 cgggctggag ctgcaagcgt aagtatatag ctcactttgt taacaacttt aactactctt
    25381 taatgcagta ttaaagacta atcggtaaca aagtgagctg ttatgactga taaaaccatt
    25441 gcgttttcgc tactcgatct ggcccccatc cccgaaggtt cttcagcgcg ggaagcgttc
    25501 tcccactctc tcgacctcgc ccgtctggct gaaaagcgcg gctatcatcg ctactggctg
    25561 gcagaacacc acaatatgac cggcattgcc agtgctgcaa cgtcggtgtt aattggctat
    25621 ctggcggcga ataccaccac gctgcatctg gggtctggcg gcgtgatgtt gcctaaccac
    25681 tcaccgttgg tcattgccga acagttcggc acgcttaata cgctctatcc ggggcgaatc
    25741 gatttggggc tgggtcgcgc gccgggtagc gaccaacgga caatgatggc gctacgtcgt
    25801 catatgagcg gcgatattga taatttccct cgcgatgtcg cggaactggt ggactggttt
    25861 gatgcccgcg atcccaatcc gcatgtgcgc cctgtaccgg gctatggcga gaaaatcccg
    25921 gtgtggttgc taggctccag cctttacagt gcacaactgg cggcgcagct tggtctgccg
    25981 ttcgcgtttg cctcacactt cgcgccggat atgctgttcc aggcgctgca tctttatcgc
    26041 agcaacttca aaccgtcggc acggctggag aaaccgtatg cgatggtgtg catcaatatt
    26101 attgccgccg acagtaaccg cgacgctgag tttctgttta cctcaatgca gcaagccttt
    26161 gtgaagctgc gtcgcggcga aaccgggcaa ctgccgccac cgattcaaaa tatggatcag
    26221 ttctggtcac cgtccgaaca gtatggcgtg cagcaggcgc taagtatgtc gctggtgggc
    26281 gataaagcga aagtgcgtca tggcttgcag tcgatcctgc gcgaaaccga cgccgatgag
    26341 attatggtta acgggcagat tttcgaccac caggcacgcc tgcattcgtt tgagctggcg
    26401 atggatgtga aggaagagtt gttggggtag tgtgttttaa cgtaggaagc cttatccgag
    26461 atggcaacgc tgtcctacgt aggcctgata agcgaagcgc atcaggcatt gtgtaggcag
    26521 cagaaatgtc ggataaggca cctctgatta ctgatacacc ggcagcacat taaagctcga
    26581 taagatatgc accagtgcgt tgccgacgcc aaacaccaga atcagcacaa tcatcggctt
    26641 gccgccccat acacggaatt tcgggctacc aaagcgttta cgcgatgcgc gggccagcag
    26701 cgccggaaca attgccgccc agatggtagc cgctaagcca gcataaccaa tggcgtacag
    26761 gaatccgtta ggaaacagca ggccacccac aaccggcggg gcaaaggtca gcaacgctgt
    26821 tttcaaacgg cccacagccg agtcgtcgaa accaaacaga tctgccagat agtcaaacag
    26881 gcccagcgtt acgccaagga acgaactcgc taccgcaaag tttgagaaca caaccagcag
    26941 aaggtccagg ctacggctgt tcagtacgcc gcttaacgcc tgtaccagca catcaatatt
    27001 accgcccttc tcggcgatgc cgataaactc cggacgcggg atgttaccca tcgtcgccag
    27061 caaccagatg gtatacagcg ccagcgccat cagcgtaccg tacaccaggc atttcacgat
    27121 ggttttcgga tctttgccgt aatacttcat caggctcggt acgttaccgt gataaccaaa
    27181 cgatgccaga cagaacggca gcgtcatcaa cagatacggt gcataagacg cattgctttc
    27241 ggcgacgttg aacaatgtcg caggctgcac atgccccagc aggctaccga aggtgaggaa
    27301 gaaggtaatg actttcgccc ccagcacaat cgctgtcatg cgactgacgg ctttggtgct
    27361 caaccacacc acaaacgcca ccaacagtgc aaaaccaaaa cccgctgccc gtgccgggac
    27421 gtttagcgac atctctgcga aggtgtgatg cagaatcgaa ccactggcag aaatataggc
    27481 ataggtcagg atgtagagca caaaggcaat ggaaatgccg ttgaccacgt tccagccttt
    27541 gccgagcagg tctttggtga tggtgtcaaa gctcgaaccg attcggtaat tcaggttagc
    27601 ttccagaatc atcaagccgg aatgcagcat acagaaccag gtgaaaatca gcgccgccat
    27661 tgaccagaag aaccacgccc cggacatgac cactggcaga gaaaacatcc ctgcgccaat
    27721 aatggtgccg ccgataatca ccacgccgcc aagcagcgac ggtgacgttt gggtggtggt
    27781 tagtgttgcc atgagggctt ctctccagtg aaaaatagtg cgactgcgtt gttatgcatt
    27841 gcactgtacc agtacatgag tacaaaaaac agaaaaaaag ccccgatggg taaaatcggg
    27901 gctgtatata ttattttaca gattgtgttc gctgttcagc gatgattacg catcaccacc
    27961 gaaacgacga cgaccggtag agtcatcacg acgcggtgcg cggccttcac gacgttcgcc
    28021 gctaaaacga cgcccatcac cacggccacc ttcacggcgt tcaccgctga agttacgacc
    28081 gccttcacga cgttcgccac cgaaaccacg accaccgcca cgacgctcac cgccagtatg
    28141 cggctgtgca tcgcccagta actgcatgtt cattggcttg ttgagaatgc gagtacgcgt
    28201 aaagtgttgc agcacttcac ccggcatacc tttcggcagt tcgatggtgg agtgagaagc
    28261 aaacagcttg atgttaccga tgtaacggct gctgatgtcg ccttcgttag caatcgcgcc
    28321 aacgatatga cgaacttcaa caccatcatc gcggcccact tcaatacggt acaactgcat
    28381 atcgccaaca tcacgacgtt cgcgacgcgg acgatcttca cggtcgccac gcgggccacg
    28441 gtcgttacga tcgcgcggac cacggtcatc acggtcacgg aattcacgtt tcggacgcat
    28501 cggcgcatct ggcggaacaa tcagagtacg ttcaccctgt gccattttca gtagtgcggc
    28561 tgccagagtt tcgagatcca gctcttcacc ttcggcagtc ggctgaattt tgctcagcag
    28621 tgcacggtat tgatccagat cgctgctttc cagctgctgc tgtactttag cggcaaattt
    28681 ttccagacga cgtttgccca gcagttctgc gttcggcagt tctacttccg gaatggtcag
    28741 cttcatggtg cgttcgatgt tgcgcagcag acgacgctca cggttctcaa cgaacagcag
    28801 tgcacgacca gcacgacctg cacgaccggt acgaccgata cggtgaacgt aagactcaga
    28861 atccatcggg atatcgtagt taaccaccag gctgatacgc tcaacgtcca ggccacgggc
    28921 tgcaacgtcg gtcgcaatca ggatgtccag acgaccatct ttcaggcgtt ccagtgtctg
    28981 ctcacgcagc gcctggttca tgtcaccgtt cagcgcggcg ctgttgtagc cgttacgctc
    29041 aagagcttct gccacttcca gagtcgcgtt tttggtacga acgaagataa tcgccgcatc
    29101 aaaatcttcc gcttccagga aacgtaccag tgcttcgttt ttacgcatac cccagacagt
    29161 ccagtagctc tggctgatgt caggacgggt agtcacgctg gactgaatgc gcacttcctg
    29221 cggctctttc ataaagcggc gggtaatgcg acgaatcgct tccggcatgg ttgcagagaa
    29281 cagagcggtc tgatgacctt ccgggatctg cgccataatg gtttcaacgt cttcgatgaa
    29341 gcccatgcgc agcatttcgt cagcttcatc cagaaccaga ccgctcagtt tagagaggtc
    29401 cagagtgcca cgtttcaggt ggtccagcag acggcccggt gtaccgacaa cgatctgcgg
    29461 cccctgacgc agggcgcgta attgcacgtc ataacgttgg ccgccgtaca gggcaaccac
    29521 gtttacgccg cgcatgtgtt tagagaaatc cgtcattgct tcagcaacct gtaccgccag
    29581 ttcgcgggtc ggtgccagca ccagaatctg tggtgctttc agctcaggat caagattctg
    29641 cagcagaggt aaagagaatg ctgcagtttt tccgctcccc gtctgggcca tacccagaac
    29701 gtcgcggcca ttcagcagat gtggaataca ctctgcctga attggagatg gtttttcgta
    29761 acccagatcg ttaagggctt caaggatagg agccttcagg cccagatctg caaaagtggt
    29821 ttcgaattca gccatgtagt acgtgtgcct caaaattaat ggcggccagt ctacataact
    29881 catcatgaaa ttgatcagca attttcattg aaaagtgtga accggctcaa agtaggtgta
    29941 ttaacgaaca acaacgccct cacccgttaa ggtgatggca atcaaaaaag attacgggct
    30001 gatgtgtacg tcagctattg ctggtccgat tctgccaggt catcttggtc ctggcccagg
    30061 agcgataatt ccaacaatgc gtatcggtgc tcaacaaagt tatgaacgtt gttggcaacc
    30121 gccagtttga acagtgccgt ggcgctgtcc aaatccccca gacttaggta gtacttacct
    30181 aaatagaagt tggtttcact gagatgctca gcgagcgagg tgttatccgt tgcgtccgcc
    30241 ttgagccttt ccattaacgt ttgttcgcta atgttgccca ggtagaactc gacaatgttc
    30301 catccccact gttccttatc cgatttttcg aagtgctgtt tcaacacttc tttagcctgc
    30361 ttctcatcga gcttctgctc ggcgagataa agccacagac tacggaaagg atcattggga
    30421 tcgtcttgat aaaacgccag cagatcatct tgcgctaact tgtcacgacc gccgtaatat
    30481 aatgcgatcc cgcgattcaa gtgcgcgtag ttgtaagttg gatcaagctc aagtacagaa
    30541 tcaaacgctt cataggcagc atcaaaattg cctgcctgcg ttaaatatat gcctaagtaa
    30601 ttgaatactt caggcatatc cggtcggatt gccagcgctt gcgaaaaatc gttacgcgct
    30661 aatgccctca gaccgagact atcatacaac actccgcgct catataaaag ctgtgcgcgt
    30721 tcgtcatcgg ttaaagcccg actggcaagg atttgttcca tacgtgccag aatcacttcc
    30781 tgctgtaaag tcggttgcaa tggtaccgcg aggacttcac ttttacgcca ggaagtatta
    30841 ctgcatcctg caagcgtaag tgctgtcgca acgaaacacc agcgcaaaaa aggcttcatt
    30901 tcccactccc gaagaccacg gttgaatgaa cgtcctgttc ccggttgcta acaaggcgtc
    30961 ctgcccggtt aaaagccccc cgccgcagcg gagggcaaat ggcaacctta ctcgccctgt
    31021 tcagcagccg gagcttccgg tgctgcagca ggttgagact gctcagtcgc ttctttaatg
    31081 ctcagacgga tacggccctg gcgatcaact tccagaactt tcaccggtac ttcctgaccc
    31141 atctgcaggt aatcggtcac tttctcaacg cgtttatcag cgatttgaga gatgtggacc
    31201 agaccttctt taccgccgcc gatggcaaca aatgcgccaa agtcaacgat tcgggtcact
    31261 ttaccattgt agacgcggcc tacttcgatt tctgcagtga tctcttcgat acgacgaata
    31321 gcgtttttcg ccttctcgcc gtcggtcgct gcgatcttca cagtaccgtc atcttcgatt
    31381 tcgatggtag tgccagtttc ttcggtcaga gcacggatta cagaaccgcc tttaccgata
    31441 acgtctttga tcttgtctgg attgatcttg atggtatgga tacgcggagc gaactcagag
    31501 atatcaccgc gcggcgcatt gatcgcctgt tccattacgc ccaggatatg cagacgcgca
    31561 cctttagcct ggttcagtgc aacctgcatg atctctttgg tgataccttc aattttgata
    31621 tccatctgca atgcagagat accgtcacga gaacccgcaa ctttgaagtc catatcgccc
    31681 aggtgatctt cgtcgcccaa aatgtcagac agtacaacgt agttgtcgcc ttctttcacc
    31741 agacccattg cgatacccgc aacggcagct ttgatcggca caccggcgtc catcagcgcc
    31801 agagacgcgc cgcacacgga agccatagaa gaggaaccgt tggattcggt gatttcagac
    31861 acaacacgta cggtgtacgg gaatttgtcc atatccggca ttactgccag cacgccgcgc
    31921 ttcgccagac gaccgtgacc aatttcacga cgcttcggag aaccgaccat gccggtttcg
    31981 cctacggagt acggagggaa gttgtagtgg aacaggaagg tatcggtacg ttcgcccatc
    32041 agttcatcaa gaacctgcgc gtcacgagca gtacccagcg ttgcggtaac cagcgcctgc
    32101 gtttcaccac gggtgaacag cgcagaaccg tgagtacgcg gcagcacacc agtacgcaca
    32161 tccagaccac ggatcatatc tttttcacga ccgtcgatac gcggttcgcc ggccagtacg
    32221 cggctacgaa caacattttt ctcgatagcg tgcagaattt cacccagttc gttttcgtcc
    32281 agggtttcgt cttcagcaag cagtgtcgcg atggtttcag atttgatgac atcaacctgc
    32341 gcataacgct cttgtttgtc ggtgatgcgg taagcatcgc tcagacgagc ttcagccagc
    32401 gcagcaacgc gcgcgttcag cgcttcgttt accggctccg gctgccaatc ccaacgcggt
    32461 ttaccggctt ctttcaccag ttcattgatg ttctgaataa caacctgctg ttgttcatga
    32521 ccgaacacca ctgcgcccag catttggtct tcgctcagca gttcagcttc agattcaacc
    32581 atcagcacgg cagcttctgt accggcaaca accaggtcca gtttgctctc tttcagttcg
    32641 tcctgagtcg ggttcagtac gtactggtca ttgatgtaac ctacacgggc agcaccaatc
    32701 gggccattga acggaatacc agacagagac agtgctgcgg aagcaccaat catcgcgacg
    32761 atatccgggt taacctgcgg gttaacagaa accacggtgg cgataacctg aacttcgttg
    32821 acgaagcctt ccgggaacag cgggcgaatc gggcggtcaa tcagacgcgc gatcagggtt
    32881 tcgccttcgc ttgggcggcc ttcacgacgg aagaagctac ccgggatacg accagcagcg
    32941 taggtacgct cctgatagtt aacggtcagc gggaagaagt cctgacctgg tttggctttt
    33001 ttctgaccaa caacggtaac aaataccgcg gtgtcatcca tgctaaccat aacagcggca
    33061 gtagcctgac gagccatcat gccggtttcc agagtcacgg tgtgttggcc gtactggaat
    33121 ttacgaacga tcggattaag caatgtaata tcctttctct ttcttagaca gtaccttacg
    33181 gtactggtgt taatacccga tcttctgcgc atcctcgcga ctaatgacaa ccctaaccca
    33241 gctctatgtg ggtaaagcct ctcattagcc gcgcgaacct ctgcaacgga agatcattca
    33301 tagcaacaat acattagttt ccagtgaatt gctgccgtca gcttgaaaaa aggggccact
    33361 caggccccct tttctgaaac tcgcaagaat tagcgacgca gacccaggcg ctcgatgagc
    33421 tgggtgtaac gtgctacgtc tttacgtttc aggtagtcga gcagtttacg acgctgagaa
    33481 accatgcgca gcagaccacg acggctgtgg tgatcttttt tgtgctctgc aaagtggccc
    33541 tgcaggtggt tgatctgtgc agtcagcagt gctacctgaa cttcggtaga accggtgtcg
    33601 tttgcgtcac gaccaaactc agaaacgatt ttagctgttg cttcagtact tagagacatt
    33661 ttaaaactcc aaagtatata gaatgaaagg acgccgatct ctaattcagc gatcccagtg
    33721 tacgttacgc aaagtgttaa acaatttacg cgacgttaag cggcagtatt ctactcgtag
    33781 cgacctgtta tcgcaagacg gttaacatta cgccgggtat tcaaccacca ggcgacgagg
    33841 cgcaacgcgg ccttcatcgt caatttcgcc cataccgata aacttgccgt tctcaccctc
    33901 tgtaacgcga accagtcctt ccagcggcgc accggatgta cgaactgggt taccattttt
    33961 gaagtaaaca gaagacgtta acggaagatt caccactggg tagtccgaag ctggactgtc
    34021 cattggcatc agtaatgggt caagtaactc cgcagccgga atatcctgct gttcggcttg
    34081 ctcaaccagt tcacgcagat gttccagggt caccatccgt tcaaccggat atttacttac
    34141 cgccagacga cgcaagtaaa taacatgcgc gccacaaccg agtttttcgc cgagatcgtc
    34201 aatgatagtg cggatataag tgccttttga gcagtgaatt tccagctcca gctcattgcc
    34261 ttcatggcga ataaacagca attcataaac ggtaatcggg cgcgcttcac gtggaacttc
    34321 aatgccctga cgcgcgtatt cgtacagttt tttgccctga tatttcagtg ctgaatacat
    34381 cgaaggaatc tgttcgatat cgccacggaa ggtatccagc gccgccgcca gttgctctgc
    34441 actaaaggtt accggacgtt cttcaacgat ttgtccgtcg gcatcagaag tatcggtacg
    34501 ctgtccaaga cgcgcaatga cccgataacg tttgtcggag tccagcagat actgggaaaa
    34561 cttcgtcgct tccccgaggc aaattggcaa catgccggtc gccagcgggt ccagcgcacc
    34621 ggtatgcccg gcacggttgg cgttataaat ccgtttcact ttttgcagcg catcgttgct
    34681 ggacatcccc tgcggtttat ccagcaacaa aacgccgtta atgtcgcgac cgcgacgacg
    34741 aggacgactc attagtcctc cttgctgtcg tccgggttaa cacgacgttc ttcgtcatgt
    34801 ttgaccacgc tggtcaccag gtttgacatg cgcatccctt caaccagaga gttgtcgtag
    34861 aagaaggtca gttccggcac gatacgcagg cgcatcgctt tccccagcag gctgcggatg
    34921 aaaccagaag cttcctgcaa cgctttgatg cccgctttaa ccgcgtcttc atctttgtcg
    34981 ttgaggaacg tcacatatac tttggcatac gccaggtcgc gagacatttc gacaccggaa
    35041 acggtggtca tcatgcccag acgaggatct ttaatttcac gctgcaggat gagagcgatc
    35101 tctttttgca tttcctgcgc tacgcgctgc gggcgaccaa attctttcgc cataataaat
    35161 tctcctgaca aaaaaggggc tgttagcccc tttttaaaat taatttcagg tggaagggct
    35221 gttcacgttg gcctgataag acgcgccagc gtcgcatcag gcaatccata caggatgcgg
    35281 cataaacgcc ttatcccgca tggaacccta aaaaccttaa gcgatggtac gttggatctc
    35341 gatgatttcg aatacttcga tcacatcgcc agtgcggaca tcgttgtagt tcttaacgcc
    35401 gataccacat tccataccgt tacggacttc gttaacgtca tctttgaagc gtcgcaggga
    35461 ctccagctcg ccttcgtaga taaccacgtt gtcgcgcaga acgcggatcg ggttgtgacg
    35521 tttaaccaca ccttcggtaa ccatacaacc tgcgatagca ccaaatttcg gtgatttgaa
    35581 cacgtcacga acttccgcca gaccgataat ctgctgtttc agttccggag acagcatacc
    35641 gctcatcgcc gctttcactt cgtcgatcag gttatagatg acggagtagt aacgcagatc
    35701 caggctttcc gcttcaatca ctttacgtgc agaggcatca gcacgtacgt tgaagccaac
    35761 caggatggcg ttggacgccg cagccagggt agcgtcggtt tcggtgatac cacctacgcc
    35821 agaaccgatg atcttcactt taacttcgtc agtagacagt ttcagcaagg agtcagaaat
    35881 tgcttccaca gaaccctgta cgtctgcctt caggacgata ttcacttcgt gaacttcgcc
    35941 ttcggtcatg ttggcgaaca tgttctcgag tttagatttc tgctgacgcg ccagtttaac
    36001 ttcgcggaat ttaccctgac gataaagtgc aacttcacgc gctttcttct cgtcacgtac
    36061 aacggtaact tcatcacccg cagccggtac gccggacagg ccgaggattt ccaccggaat
    36121 ggacggaccc gcttccagca cttcctgacc cagttcgtta cgcattgcac gaacacgacc
    36181 gtattcgaag ccacacagaa cgatatcgcc cttgtgcaga gtaccttcac gtaccagaac
    36241 ggtagcaacc ggaccacgac ctttatcgag gaaggattcg ataaccgcac cgctcgccat
    36301 acctttacgt accgctttca gctccagaac ttccgcctgc agcaggatag catccagcag
    36361 ttcatcaata ccggtacccg cttttgcaga tacgtgtacg aactggcttt cgccgcccca
    36421 ctcttctggc aggatgccgt actgggagag ttcgttctta acgcgatccg gatcggcttc
    36481 tggtttatcg attttgttca cagcaaccac caccggaaca cccgccgctt tcgcgtgctg
    36541 gatagcttcg atggtctgcg gcattacacc gtcgtctgca gcaacaacca ggactacgat
    36601 gtccgttgcc tgcgcaccac gtgcacgcat tgaagtaaac gcggcgtgcc ccggggtgtc
    36661 caggaaggtg atcatgccgt tttcagtttc aacgtggtat gcaccaatgt gctgggtaat
    36721 gccgcccgct tcgccagagg ccactttcgt tgaacgaatg tagtccagca gagaggtttt
    36781 accgtggtca acgtgaccca tgatggtcac aaccggcgcg cgcggttcag ccgcagcacc
    36841 cgtgtcacgg tcgctcatta ccgcctcttc cagctcgttt tcacgacgca ggataacttt
    36901 gtggcccatc tcttcagcaa ccagctgtgc ggtttcctga tcgataacct ggttgatggt
    36961 tgccattgcg cccagtttca tcatcgcttt gatgacctga gagcctttaa ccgccatctt
    37021 gttcgccagt tcgccaacgg tgatggtttc gccgatcaca acgtcacggt taacggcctg
    37081 agctggcttc tggaagcctt gctgcagcga agaaccttta cgttttccgc ccttaccgcc
    37141 acgtactgct gcacgagctt cttcacgatc agcttttgat tcagcgtgtt tgttgccttt
    37201 cttcggacgc gctgctttcg cgttacgacc acggccacgg ccgccttcga cttcacgatc
    37261 gctttcgtct tctgcctggc gagcatgttg agaagtagtg acgtgataat cgctggaatc
    37321 ttcagtcggt tccgcgttat cagtccattt gttttcttcc gccatacgac gtgcttcttc
    37381 agcaacgcga cgtgcttctt cttcgagttt acgacgcgct tcttcttcgg ctttacgctt
    37441 gagctctgca gcttcctgct cacggcgggc tttttcagcc tgggcgtttt tagtcatatc
    37501 gtcttgttga ttgctcactt tgtctttttc cgcagcttca cgtttcgctt gttcagcagc
    37561 ttcacgctta gcttgttctg cggcctcacg ttcagctttt tgttgcgcct cgcgtttagc
    37621 cgattcttct gcctcacgac gggcttgctc ttccgcttca cgctgcgctt gctcttccgc
    37681 tgcaaggcgc tcagcctctt gcggatcgcg tttcacaaag gtgcgtttct tgcggacttc
    37741 gatttgtacc gatttgcttt ttccaccggt accaggaatg ttaagggtgc tgcgtgtttt
    37801 acgttgcagc gtcaatttgt ccgggcctga atttttctga ttcaggtggt caatcaaagt
    37861 ctgtttctct tgtgcagaca cagagtcgtc agcagacttc cggatacctg catcagcaaa
    37921 ttgctgtacc aggcgttcca cggaggtctg tcgctctgcg gccagcgttt taatcgttac
    37981 atctgtcatg ctgttccttc ctgctacagt ttattacgct tcgtcaccga accagcaaat
    38041 attacgggca gccataatca gtgctccggc tttttcgtcg gtcaaccctt cgatatcagc
    38101 cagatcatca atgccctgtt cggcgagatc ttccagcgta caaacgccac gggcggccag
    38161 tttgaatgcc aaatcacgat ctaccccttc aaggttcagc agatcatcag ccggtttgtt
    38221 atcaccgagg ctttcttcct gggcctgtgc aatggtggcc agtgcatttt tagcacgctc
    38281 gcgcagtgct tcaacggtcg gctcatcaag gccttcgatt tccaacagct ctttcatcgg
    38341 cacataggcc agttcttcca gcgtcgagaa gccttcttct accagaacag tcgcgaagtc
    38401 ttcatcgatg tcgagatatt tggtgaaggt gtcgatcgct gcgtgcgctt ccgcctgatg
    38461 cttagcctgc aggtcgtcaa cggtcatcac gttgagttcc caaccgctca gctgcgaagc
    38521 cagacgcacg ttctgaccgt tacggccaat cgcctgcgcc aggttaccgg cttcaacggc
    38581 gatatccatg gtgtgtttat cttcatccac cacgatagaa gcaacgtctg ccggtgccat
    38641 tgcgttaatc acgaactgcg ccgggttatc atcccacagg acgatatcga tacgctctcc
    38701 gcccagttca gtagaaaccg cctgaacacg cgcgccacgc atacctacgc aagcacctac
    38761 cggatcgata cgtttatcgt tggttttcac cgcaattttc gcacgagatc ccgggtcgcg
    38821 agccgctgct ttaatttcaa tcacttcttc gccgatttcc ggcacttcaa tacggaacag
    38881 ttcgatcagc atttccggct tggagcgggt gacgaacagc tgcgcgccac gcgcttccgg
    38941 gcgaacggaa tagagcacgc cacgaacgcg gtcgccaggg cggaagtttt cacgcggcag
    39001 catatcttcg cgcaggatca cggcttcagc gttgttgccc agatccagag agatgttgtc
    39061 gcggtttact tttttcacca cgccggtgat gatttcacct tcgtgttcac ggaactgatc
    39121 aaccaccatc gcacgttcgg cttcacgcac tttctgcacg ataacctgtt ttgccgtctg
    39181 ggtagtgata cgatcaaagg taacagactc aatctgatct tcaacgtaat cgcccaagtt
    39241 caggctttca tcttcataac gtgcggcttc aagggtgatt tccttggtcg gctgggtgac
    39301 ttcatcaaca actaaccagc gacggaaggt gtcaaaatca ccgcttttgc gatcgatctg
    39361 tacgcgaacg tcgatttctt gttcatattt tttctttgtt gctgtcgcca gcgcgctttc
    39421 caatgcttcg aaaatcttct cgcgaggtag cgccttttca ttggatacgg cttcaactac
    39481 agccaaaatt tctttgttca tcgcgggctt ttcacctcat ccagactatt aaaagtgggg
    39541 aaccaggttc gccttctgga tattactcag cgcgaacact tcatctttac cttcgacggt
    39601 aactgtgatc atttcaccgt ctaccgcttt gataacgccc tgccatttac gacggttttg
    39661 taccgccata cggagaacca gagtcacctc ttctccgaca aaacgggcgt agtgttcagc
    39721 cgtgaacagt gggcgatcga gacccggtga ggagacttcc aggttataag caacggtgat
    39781 ggggtcttca acatccagca cagcacttac ctggtggctc acatcagcac aatcatcaac
    39841 attgatgcca tcttcactat caatatagat gcgcagtgtg gatgtgcgac cgcgaataaa
    39901 ttcgatgcca accagttcaa aacccagggc ctcaactggc gcagtaatca tctctgttaa
    39961 tttttgctct aatgtggaca agcccacccc caagacataa aaaaagggcc taaagcccag
    40021 ttattctgta gtcagataac aaaaaacccc gataaatcgg ggctttatat aactgaaccc
    40081 tataaccgca actgcggtct ggagcacttt ccagaaggat tttttcaaat cccactacga
    40141 aggccgaagt cttcacagta tatttgaaaa aggactctaa gggaaagtgg ttgcgggggc
    40201 cggatttgaa ccgacgacct tcgggttatg agcccgacga gctaccaggc tgctccaccc
    40261 cgcgcctgaa acgtggcaaa ttctactcgt tttgggtaaa aaatgcaaat actgctggga
    40321 tttggtgtac cgagacggga cgtaaaatct gcgggcatta tagtgatcca cgccacattt
    40381 tgtcaacgtt tattgctaat cacgtgaatg aatatccagt tcactttcat ttgttgaata
    40441 cttttacctt ctcctgcttt cccttaagcg cattatttta caaaaaacac actaaactct
    40501 tcctgtctcc gataaaagat gattaaatga aaactcattt attttgcata aaaattcagt
    40561 gagagcagaa atccaggctc atcatcagtt aattaagcag ggtgttattt tatgacgacg
    40621 attctcaagc atctcccggt aggtcaacgt attggtatcg ctttttccgg cggtctggac
    40681 accagtgccg cactgctgtg gatgcgacaa aagggagctg ttccttatgc atatactgca
    40741 aacctgggcc agccagacga agaggattat gatgcgatcc ctcgtcgtgc catggaatac
    40801 ggcgcggaga acgcacgtct gatcgactgc cgcaaacaac tggtggccga aggtattgcc
    40861 gctattcagt gtggcgcatt tcataacacc actggtggac tgacctattt caacacgacg
    40921 ccgctgggcc gcgccgtgac cggcaccatg ctggttgctg ctatgaaaga agatggcgtg
    40981 aatatctggg gtgacggcag cacctataaa ggaaacgata tcgaacgttt ctaccgttac
    41041 ggtctgctga ccaatgctga actgcagatt tacaaaccgt ggcttgatac tgactttatt
    41101 gatgaactgg gcggccgtca tgagatgtct gaatttatga ttgcctgcgg tttcgactac
    41161 aaaatgtctg tcgaaaaagc ttactccacg gactccaaca tgcttggtgc aacgcatgaa
    41221 gcgaaggatc tggaatacct caactccagc gtcaaaatcg tcaacccaat tatgggcgtg
    41281 aagttttggg atgagagcgt gaaaatcccg gcagaagaag tcacagtacg ctttgagcaa
    41341 ggtcatccgg tggcgctgaa cggtaaaacc tttagcgacg acgtagaaat gatgctggaa
    41401 gctaaccgca tcggcggtcg tcacggcctg ggcatgagcg accagattga aaaccgtatc
    41461 atcgaagcaa aaagccgcgg catttatgaa gcccctggga tggcactgct gcacattgcg
    41521 tatgaacgtt tgttgaccgg tattcacaac gaagacacca ttgagcagta tcacgcgcat
    41581 ggtcgtcagt tgggccgtct gctgtaccag ggacgttggt ttgactccca ggcgctgatg
    41641 ctgcgggact ctctgcaacg ctgggttgcc agccagatca ctggtgaagt tactctggag
    41701 ctgcgccgcg ggaacgatta ttcaatcctg aataccgtct cagagaacct gacctacaag
    41761 ccagagcgtc tgacgatgga aaaaggcgac tcggtgttct cgccagatga tcgtatcggt
    41821 caactgacca tgcgtaacct ggatatcacc gatacccgcg agaaactttt cggttatgcc
    41881 aaaactggcc tgctctcctc ctctgccgct tcaggggtgc cgcaggtgga gaatctggaa
    41941 aataaaggcc agtaattcga catcaaccct gcccttcagg ggtggggtta ccttgattat
    42001 cctctgtaaa ctcctttctg agcatcacat aatcgaaaac atcatggttt gcatccacaa
    42061 cccgcgagtc tcctttatag tgtgcaatca cttcctcaag cgtttgcggc tgttccggct
    42121 ttgttacccc catccacgca ttaataatgt aattattgta agctgtcgaa aagatgttgt
    42181 tttccgttgt gcgatccacg ccatccccaa gaacggggct ataccagata aacataggga
    42241 catgatatgc ctgctggcta gcctccctgc ctccatgaaa atagacgttc ttcttcgtag
    42301 ggtcgcgttc caggccgtgg tcggcaaaat acatgaccga ggcgcggcga tcttttaata
    42361 attcaaaaac ctgacctagc aaactatctg tgtaatgaat ggagttgtca tagcaggcat
    42421 cctgatcgtc ctgcggttga aacacagcgc tggattgcgg ataggcgcta caagccggtt
    42481 catggcttcc atttaaatga agaacaatca gtttcttttg ctgcgtcttt tgctgtaacg
    42541 cttgcgataa atgcggcaac aacaattcat caaatcctct gacatagact gtttccatgg
    42601 cgcgcatggc gatactggta actgctgtac cattctgccg aaaagcggat tgcgagctta
    42661 gccagaaagt ctgaaatcct gcttgattag ccatattaat aatgttgtcc ggataattat
    42721 gaatgtcatg actcaaaaca gaatcagcag ttaaagaaag gggaaccgac agcgcagtgt
    42781 aaggtgcacc gcttattgct tgattaaaca gtttgatctg ctttctttgt gcttcgactt
    42841 gcggtgtcgt agagtgtgta tatccataca aagacatatt gtcgacacgt acagactccc
    42901 ccacaatcaa cacgtaggta tcaatacctg tatccctgac tgataattga aaatacggca
    42961 ccgtgtttgc aattgagagt aatctttgat gctctttcgc tgctaaagca aaataattga
    43021 gattgaaaaa cggcgtatag gtagcaaatc gcgacgctag tatatatgga ctgaacgcct
    43081 ctttattttt tgcatcttta taagcaaatt gacaagcgga aaataaactg cccgaaatga
    43141 caatcagcaa taatattcct gtcacttttt ttgtcggcaa ggaaacatca tattttatta
    43201 ttactgccaa aaaaagaagg gataaaaagg caaaagcaca tagataaggg atatacattc
    43261 ccagcatttt gacaacttca tccggatcac tctgcagcac actaatcgca aatccatcat
    43321 tgaaagttgt accaaagata caccatgaat agaggctaat actcatatct gccgcagtca
    43381 gtaacacaaa tggtgcggca ataagcaggc gaagcggaag ggatggtata cgtttaacaa
    43441 ccaggatggt cagaacgaag aacagcaatc gctgaaccat atgcgctccg gaagaagcga
    43501 ctaagttcgt aataccaaaa ataataacac aaagatacaa caaccaatga gatttaaaac
    43561 ttttaacaaa tttgttgaat actgtcatcc agaaatccaa gttcacaacc aatataaaca
    43621 attatcaaca atgttcaatt ttatatcaga catgtttttc aactctaatc catatcagac
    43681 cgaaacactg ctagattttt tctttttaaa tgatgcggcc attgcgttct cagtaattaa
    43741 ataacattat caatgcgtct ctaaacatta cgcagaacgt agccatcagt agttatactg
    43801 acaggggcag gatggtttat cgagaagtaa acatatccgt attcgtaccg gaaatggagt
    43861 tgacacaata aagtgccaat tatgtcagca gaagggaaaa gcttataact aaggcatacc
    43921 ggcaccatcg tttcaaggta ccagctacga gtaaaacaac tggacgagat acagatacct
    43981 gacaaccatt cctcagacca ggaccaaaac gaaaaaagac gcttttcagc gtctttctgg
    44041 aatttggtac cgaggacggg acttgaaccc gtaagcccta ttgggcacta ccacctcaag
    44101 gtagcgtgtc taccaattcc accacctcgg cacggatact actttttagt tcgggatatc
    44161 gctggtcggc ttagccggag cagctggctg agtttgttcg gttttcgccg gcgcactcag
    44221 gttttcccat tcgctacctt tattggtttt gttgctattg atgttaccca gcaccagact
    44281 gatgatgaag aataacgttg ccagcagcgc cgtcatgcga gtcatgaagt taccagaacc
    44341 acttgaacca aacagcgtag cggaagcgcc tgctccgaag gaggctccca tatcagcgcc
    44401 tttaccttgc tgcagcatga tcagaccaac aaggccaatt gccacaataa ggaaaactac
    44461 taaaagagct tcgtacataa tcaacctgtt ccttgcggag ttgccgcgta ccaatgcttc
    44521 aaccaataaa gcgggaatat ttaacctttc ccactgaagc gggtgtgaat actaaccaaa
    44581 gcgaatgacc ttcgcaaggg caattttatt gcattgtatc aactgcggaa aaaaacagca
    44641 aaaccgatgt gttcgctgag aaaaaaggcg acaatcgccg cctttttagc cagccattta
    44701 tcgttttaaa cggcttttac tgcatcggcg atgcggtgtg caaattcagt cacctgcgct
    44761 tcgtcttcgc cttccaccat cacgcgaatt aacggttcgg tgccggattt acgcaacagc
    44821 acacgtccac ggctacccag cgccgcttca acttctgcgg tcacagcttt gactgattca
    44881 tgctccaacg gatcgccgct acctgcggtg taacgcacat taaccagaat ctgcgggaac
    44941 attttcatgc cgctgcaaag gtcgtgcagg ctcatatggt tacgcgccat cgccgccagc
    45001 acctgcaagc cagcaacaat gccgtcaccg gtagtggttt tatccagcag gatcacatga
    45061 ccggagttct ctgcaccgat acgccagcct ttctcctgca ttttttccag tacgtagcgg
    45121 tcacccactt tcgcgcgcgc aaatggaata cctaactgtt tcagcgccag ttcaagcccc
    45181 atgttgctca tcaatgtacc cacagcacca ccacgcagct ggccctgacg aagaccttca
    45241 cgcgcgatga tatacatgat ctgatcgcca tcgactttat tgccttcatg gtcaaccata
    45301 atcacgcgat cgccgtcgcc gtcgaaggca ataccgagat ccgctttttc agccagcaca
    45361 cgagcctgga gcgcgcgaac gtcggtagcc cccacttcgg cattgatatt tacaccgttc
    45421 ggctcacaac cgatagcgat aacgttcgcc cccagttcac gcagcacgtt cggtgcgatg
    45481 tgataagtcg caccgtttgc acaatccacc acaatcttca gttcactgag gctaagttcg
    45541 ttcgggaacg tggctttgca aaactcgata taacgacccg cggcatcaac gatacggctg
    45601 gctttaccca gttctgccga atcaacacag ctgatctctt tttccatttc cgcttcgatg
    45661 gcttcttcaa ctgcatccgg cagcttagta ccgtcaatag aaaagaattt aatgccgtta
    45721 tcgtagaatg ggttatgcga tgcagaaatt acaattccag cctctgcgcg gaaggtacgc
    45781 gtcagataag ccacggccgg tgttggcatc gggccagtga agagcgcgga aagaccggca
    45841 gccgcaagac ccgcttccag tgctgactcc agcatatagc cagaaatacg cgtgtcttta
    45901 ccaataataa tcttacgaga gccgtggcgc gccagcactt tacccgcggc ccaacccagc
    45961 ttaagcacaa aatcaggtgt gatcggcgca tcccctacac gaccacgaat cccatcggta
    46021 ccgaaatatt tacgattact catagcgttt gttttccttt gcagacagag tggcttccac
    46081 cacccgcatc gcttctacgg tttctttgac gtcatgaaca cgaatgatgt gcgcgccttg
    46141 cattgcggca atgaccgcac aggccagact accgctcagg cgctcggacg gccccacgtt
    46201 cagcaattgc ccaatcatcg attttcgtga catacccacc aacagcggca ggttgaaatg
    46261 gtgaaattca gccaggcgcg ccagtaatga atagttatgg gagagatttt taccgaaacc
    46321 gaatccgggg tcgagcaaca atttctcttt tgcgataccc gcctgctcgc aacgtgctat
    46381 ttgctcaata aagtagcgat tcacttctgc aaagacatcg tcatacttcg gcgcttcctg
    46441 catggttttt ggatttccct gcatatgcat cagacaaacc ggtaaaccgg tttctgcagc
    46501 cgcctccaga gcaccaggtt cggaaaggga gcggatatcg ttaataatgt gagcgccaac
    46561 tttcgctgac tcacggatga cttctggttt ggatgtatct accgagatcc agacttcgaa
    46621 gcgttgagca attgcctcaa ccacaggaat aacacgttgc aactcttctt caacgcaaac
    46681 ttccgccgcc cctgggcgcg tggactcgcc accaacgtca atgatcgtcg cgccagcgtt
    46741 gatcatcaga ttcgcatgtt tcaccgcatc taacagcgag ttatgcgtgc caccatccga
    46801 aaaggaatca ggcgtgacgt tgaggatccc cattacgtga ggatggctaa ggtccagtga
    46861 agtaccctgg gcaaagagtt tcatgatgtt atccctggta tgaattgata agaaaaaacc
    46921 ccggagcacg ccccggggtt ttcggtacaa atacagtcat ctgatacggg aacttacttg
    46981 tcgcctaact gctctgacat ggtgttaccc gggttcggcg tacgcggttc atcaaccgga
    47041 cgaggagcct ttggactacc attgtcgcca gaattgttag aagcgcctgg ttcttcccag
    47101 cccgctggcg gacgtacatc gcgacgtgcc atcaggtcat caatctgcgg tgcgtcgata
    47161 gtctcatatt tcatgagagc atctttcatc gcatgcagaa tatccatatt gtcggtcaga
    47221 agctgacgcg cacgattata gttacgctca atcagtgctt tcacttcctg gtcgatgata
    47281 cgtgcagttt catcggacat atgtttcgct ttcgctacgc tacggccgag gaacacttca
    47341 ccttcttctt ccgcgtacag cagtggaccc aatttctcag agaagcccca ctgggtcacc
    47401 atgttacgtg ccaggttggt cgcaacttta atatcgttgg acgccccggt agaaacatgt
    47461 tccggtccgt agatgatctc ttccgccaga cgaccaccgt acagcgtgga gatctgactt
    47521 tccagtttct gacggctggc gctgattgcg tcgccctcag gcaagaagaa agtcacaccc
    47581 agcgcacgac cgcgtgggat aatcgtcact ttgtgcaccg gatcgtgttc cggcaccagg
    47641 cgaccgataa tcgcatgacc cgcctcgtgg taagccgtcg attctttctg cgcttccgtc
    47701 atcaccatgg agcgacgttc cgcacccatc atgattttgt ctttcgcttt ctcgaactca
    47761 accatcgaaa caacgcgttt gttgccacga gcagcgaaca gtgccgcttc gttcaccagg
    47821 ttcgccaggt cagcaccgga gaaaccagga gtaccacggg caatgattgc cgcgtcgata
    47881 tcgggtgcca atggtacgcg acgcatgtga actttcagga tctgctcacg accgcgaaca
    47941 tctggcaagc caaccacaac ctgacggtcg aaacggccag gacgcagcag ggctgggtcg
    48001 agaacgtccg gacggttagt cgcagcgata acgatgatac cttcgttacc ttcaaaacca
    48061 tccatctcaa ccagcatctg gttcagagtc tgttcacgtt catcgtgacc accgcccaag
    48121 cctgcgccgc gctggcggcc tacggcgtcg atttcatcga taaagatgat gcacggtgcc
    48181 gctttcttcg cctgttcgaa catgtcacga acacgggatg cacccacacc gacgaacatt
    48241 tctacgaagt cagaaccgga gatagtaaag aacggaactt tcgcttcgcc tgcaattgct
    48301 ttcgccagca acgttttacc ggtacccgga ggacctacca tcaggacgcc tttcgggatc
    48361 ttaccgccga gtttctggaa gcggctcggc tcacgcagat actcaaccag ttcagcaact
    48421 tcttcttttg cttcgtcgca gcccgcaacg tcagcaaagg tggttttgat ctgatcttcc
    48481 gtcagcatgc gcgctttgct cttaccaaac gacatggcac ctttgccacc gccgccctgc
    48541 atttgacgca tgaagaagat ccagacacca atcagcaaca gcatcgggaa ccaggagatg
    48601 aagatagaag ccagcaggct tggttcttca ggcggttcac cgacaacctt gacgttcttg
    48661 gtcaacaggt tatccagtaa tttcggatcc tgaaccggaa tgtaagtggt ataacggtta
    48721 ctatctttct tggtaacgtt gatttcacgt ccgttgatac gcgcttcacg aacctggtcg
    48781 ttattgacct cttgtaggaa ggtagagtaa tccaccttac ggccattaga ctcgctgggc
    48841 ccaaagctct ggaatactga catcagcaca acggcaatga ccagccagag tattaggttt
    48901 ttcgccatgt cactcaaggg attaacctct tattacaact gtgttaaaaa cagcgtcagg
    48961 atactctata tccagcatct ttcaaacttt cgtctgaaat ctcccggtta gggtttacgc
    49021 ccggtcgcta caatatacac ttcccgcgaa cgtgcacgag aagagtccgg cttacgaact
    49081 ttgaccttcg taaacaggga gcgaatttcc cttagatact catcgaaacc ttcgccctgg
    49141 aacaccttca ctacaaaact gccacctggc gctaatacat cacgacacat ttctagcgcc
    49201 agttccacca gatacatggc acgggggata tccaccgccg gtgttccgct catgtttggt
    49261 gccatatcgg acatgacaac ctggactttg ctgtcgccaa cgcgctccag cagtgctttc
    49321 atcaccagtt catcacgaaa atcgccctga agaaagtcca caccaacgat aggatccata
    49381 ggtaaaagat cgcaagcgat gatgcggcct ttgccgccaa tttgggtgac cacatattgt
    49441 gaccaaccac ccggagcagc accaaggtcg acaaccgtca ttcccggttt aaagagtttg
    49501 tcactttgct gtatttcatc aagtttaaac caggcacggg aacgtaaccc ctttttctgt
    49561 gcctgttgaa catatttatc gctaaagtgt tcctgaagcc agcggctgga gctggcagaa
    49621 cgcttcttac ctgtcattta actttcccat ggggataact catcgtaacc aattgcgtaa
    49681 atttttacgc gcctatttgg tgatatatgg gagatggcgg tagaatgacc cgttttcaat
    49741 cccaacgtaa gcaaaaaata cgatgaatct gagtactaaa caaaaacagc acctgaaagg
    49801 tctggcacat ccgctcaagc cagttgttct gcttggcagt aatggtttga ccgaaggggt
    49861 gctggccgag attgaacaag cgttagagca ccatgaactc atcaaggtga aaatcgccac
    49921 cgaagatcgc gaaactaaaa ccttgatcgt ggaagctatc gtgcgcgaaa ccggcgcctg
    49981 taatgtacag gtcatcggta aaacgctggt gctttatcgc ccaactaaag aacgtaaaat
    50041 ctcgctgcca cgctaagatt atcctaaagt tacacacatt cgctgtgtaa aacgaggggt
    50101 tttccgcagg caggagagca aaatgccacg ctctgttcgt tgataaaagg ccgcatagcg
    50161 gcctttttcc tttctttaca atacatcaac atcttgagta ttgggtaatt cttacaggta
    50221 ttccacctta attacttcaa attctacttc gccgcccggc gttttgatga ccacaacatc
    50281 atcttcttct ttgccgatca ggccacgagc aataggcgag tttacagaaa tcaggttttg
    50341 tttaaagtca gcttcgtcat cgccaacgat gcgataagtc tgttcttcgt cagaatcgag
    50401 attcagcacc gttacggtag caccaaaaat aacgcgccca ttgttgggca ttttggtgac
    50461 atcaatcacc tgcgcgttcg acagcttggc ttcgatgtct ttgatacggc cttcgcagaa
    50521 gccctgctgt tcacgagctg cgtggtattc ggcgttttct ttcaggtcgc catgctcacg
    50581 cgcttccgcg atagcagcaa tgatttcagg acggcgcaca gatttcagaa aatccagctc
    50641 ttcgcgtaat ttttcagcgc cgcgtaaggt catcggaata gcttgcattt gttatacctc
    50701 ttgaatattc ctgatggggc aagtcttcac ccaccccggc tgttcggcct gcccggcata
    50761 actcctcacc gggaccagaa gcaaaaaaat accgacccgg gtacaagtcc caggtcagct
    50821 acaattcaca ttttgatagt cattttaccc tggagttccc gaagggtcat cgtttacttt
    50881 atagggcgtt gcgccgtagt atgacggctc gattccaggt tgttagcgcg agattatgcg
    50941 attttccaga tttatcatcg gattgaccag ctgtatagcg ttcagtgttc aggccgcaaa
    51001 tgttgatgag tacattactc aactccccgc aggtgccaac cttgccctga tggtgcaaaa
    51061 agtcggcgcg tcggcccccg ctattgatta ccacagtcag cagatggcgc tacccgccag
    51121 tacgcagaaa gtgattactg cgctggcggc gttgattcaa ctcggccccg attttcgttt
    51181 taccacgacg cttgaaacca aaggcaatgt ggaaaacggc gtacttaagg gtgacttagt
    51241 tgcgcgattt ggtgccgatc cgacgttaaa acgtcaggat attcgcaata tggtcacgac
    51301 tttgaaaaaa tctggcgtca accaaatcga tggcaatgtg ttgatagata cctccatttt
    51361 cgccagccac gataaagccc ccggctggcc atggaatgac atgacacaat gctttagcgc
    51421 accgcctgcc gccgccatag ttgaccgcaa ctgtttctcc gtctcgctct acagtgcccc
    51481 aaaacctggt gatatggctt ttatacgcgt ggcatcttat taccccgtta cgatgttcag
    51541 ccaggtacgc accctccccc gtggttctgc cgaagcgcaa tactgcgaac tggatgtcgt
    51601 accaggtgac ctgaaccgct ttacgctaac gggatgcctg ccacaacgtt ctgagccgct
    51661 cccgttggct tttgccgtgc aggatggtgc cagctatgcc ggggcaattc tgaaagatga
    51721 gttaaaacag gcgggtatcg cctggagcgg aacactgctg cgccagactc aggttaacga
    51781 acctggaacg gtagttgcca gtaaacagtc ggccccgctg cacgatctgc ttaagattat
    51841 gctgaaaaag tcggacaaca tgattgccga tacggttttc cgcatgatcg gccatgcgcg
    51901 cttcaatgtg cctggaacat ggcgggccgg atcggacgcc gtgcgtcaga tcctgcgcca
    51961 gcaagccggt gtcgatatcg gaaacaccat tattgccgat ggttcagggc tttcgcggca
    52021 taacctgatt gcccccgcca ccatgatgca ggtgctgcaa tatattgccc aacacgacaa
    52081 tgaacttaac tttatctcca tgctgccgct ggcgggctat gacggctctt tgcagtaccg
    52141 tgcaggtctg catcaggcgg gcgtggatgg aaaagtctca gcgaaaaccg gttcgttgca
    52201 gggggtatat aacctggcgg gattcattac cacagcgagc gggcaacgaa tggcgtttgt
    52261 gcaatatctt tctggctatg cagtagaacc ggcggatcag cgtaatcgcc gtattccgtt
    52321 agtgcgtttt gaaagccgtt tgtataaaga tatttatcag aataattagc ctaaagagaa
    52381 accccggcac atggccgggg ttttgctgat taacgcttgt aaatgaactc aacgccttct
    52441 tcgtcgtctt cgtcccagtc gtcatcccag tcctcatcat cctcttcagc aatctcttca
    52501 agctgctgac ggtgataatc atcccacatg aattcgactt tctctggctg tttcgcttct
    52561 tcagcctgca cgaccgggtt ttcaatgata aaggtcatca catcccagca gagatctttc
    52621 acgcccagtc cgctcgccgc agagatcaga taatatttat cttcccagcc cagcgcttca
    52681 gcgatcgctt tcgctttctc ttcggcttct gccttatcca gcagatcgat cttgttgaaa
    52741 actaaccaac gcggtttcgc cgccagatcc tggctgtatt tttccagctc actgataata
    52801 atacgcgcgt tttcaaccgg atcggtgccg tcaatcggat cgatatcgat gaggtgcaac
    52861 aggacgcggc aacgttccag gtgcttcagg aagcgaatgc ccagacctgc gccttctgca
    52921 gcgccttcaa tcagccctgg aatatcggca acaacgaagc tcttttcgtt gtccattcgc
    52981 accacgccca ggcttggtac cagagtggta aacggataat ccgccacttt cggtttagcc
    53041 gccgatacag cacgaataaa ggtcgattta cccgcgtttg gcatccccaa cataccgacg
    53101 tcagccagca gcatcagctc cagcagcagc tcacgcttat cgcccggcgt accgttagtt
    53161 ttctgccgtg gtgtacggtt aactgacgat ttgaaacgag tgttgcccag accgtgccag
    53221 ccgcccttag caaccagcag acgctgaccg tgtttggtca tatcacccat ggtttcacca
    53281 gtaccctggt cgattacacg cgtacctacc ggcactttaa tcgtgacgtc tttaccgcgc
    53341 ttacctgtac agtcgcggct tgcaccgttt tgaccgcgct ctgcacggaa agatttttca
    53401 aaacgataat cgataagcgt gttcaggttc tcgtcggctt ccatccatac gtcaccaccg
    53461 tcaccgccgt cgccgccatc cgggccgcct ttcggaatat acttttcgcg gcggaagctc
    53521 acgcaaccat taccgccatc acctgcaacg accagaatcg atgcttcatc aacaaacttc
    53581 attttattct ccgtaaatca ttcgcctgcg cggggttgcg ataccaccgt tgtatgctta
    53641 cgtaatccgc cccaaatacg atgaccaatg gcggaataca tcgcgcccgc aaccacgaca
    53701 aacgcaccga gataacctaa aaggtttaac atcggtctgg cgaagaaatc gggccaggcc
    53761 agtgataaaa gatctgaaaa aaacagcgta aacagtgggg tgagcgtgat gatcgcgctc
    53821 acctgcgctg cctgccagcg agccatcgct tccgccaggg cgccatatcc taccaatgta
    53881 ttcagtccgc aaaaaattaa acaggcgagc tgccagtggc taagctgcgc tatcactcca
    53941 ggatttgcca gagggaagag cgcaattgta cataaagtgt acagcaaaaa caggatctgc
    54001 ggtgaggcca gccgacgcaa taaaaccttt tgcgccacgc cataactcac ccaaaccgtc
    54061 gccgcaccga ccccaaagat aactccccag gtgtaatcgg tgagctttgt aaatatctcg
    54121 accagactgg tgttaaaaaa catcaccagg ccgctcagga gcatcaatgc ccctacaacc
    54181 tgagtactgc gcattttctc tttcaggata aatacgctgg caaccatcat gccaactggc
    54241 gagagttgcc caatcacctg cgaagcggtc ggactcaggt attgcaagga tgagctgaac
    54301 aggatgaagt tcccaaacag cccggcggtc gccactgcta acaaaatcaa ccagcgtggc
    54361 ttacgaaaca cgcgtaatgg cggcaaccgc ttcttcaccg caagaatggc accaaggcca
    54421 atactcgcca tcaagaaacg gtaaaacacg attgtcggag gttccatcac ctccagcacc
    54481 tgcttcattg cgattggcaa cgccccccag caaattgctg tggtgagcgc caaaagaatg
    54541 ccaatgcctg cctgctgctt cataccgtat tccctgcaaa gcgcatatgc ggattaacgt
    54601 cgcaccatgc gcatttttac cggttatcga atgtaaaaag ccccgcaacg tgttgcgggg
    54661 ctttcatccg ttaccgggac gcgaaaaact tattcagctt cgatgctgat aaatttacgg
    54721 tttttcgggc ctttaacttc gaatttcact ttaccgtctg ctttagcaaa cagagtgtgg
    54781 tcacgaccgc aacctacgtt agcgccagcg tggaatttgg taccacgttg acgaacgatg
    54841 atgctacccg ccagaacgga ttcaccaccg aaacgcttaa cgcccaggcg tttagcttct
    54901 gaatcgcgac cgttacgtgt ggagccgcca gcctttttat gtgccatttg aaatctctcc
    54961 tcaggtctta ggcgctgatg ccagtaattt tcacatcagt gaaccactga cgatggccct
    55021 gctgcttacg atagtgttta cgacgacgaa acttaacgat tttaactttc tcgccacgac
    55081 cgtgagcaac aacttcagct ttgattacgc cgccatcaac gaaaggaacg ccgattttga
    55141 cttcttcacc gtttgcgatc atcagcactt cagcgaactc aacagtttcg ccagttgcga
    55201 tgtccagctt ttccaggcga acggtctgac cttcgcttac tcggtgttgt ttaccaccac
    55261 tttggaaaac cgcgtacata taaaactccg cttccgcgca caccttttca atgattcaga
    55321 gtgcgctata aatattcaca atagggcgcg aatattacgc aaaacgcacg cctttgacaa
    55381 gtgctacagt caatacacga agaaaaaaaa cacaacttgt acggtaacgt ttatctgtgc
    55441 cattttttca gtacaatcac cctatattcc taaccataaa ccctaagttg cctttgttca
    55501 cagtaaggta atcggggcga aaagcccggc ttttgcgatg aatttagaaa aaatcaatga
    55561 gttaaccgcg caagatatgg cgggtgttaa tgcggcaatc cttgagcagc ttaattccga
    55621 cgtccaactg atcaatcagt taggctatta catcgtcagc ggcggcggta aacgtattcg
    55681 tccgatgatt gctgtactgg ctgcacgagc tgttggctat gagggaaatg cgcatgtcac
    55741 cattgctgcc ctgatcgagt ttatccacac ggcgactctg ctacacgacg acgttgtgga
    55801 tgaatcagat atgcgcaggg gtaaagctac cgccaacgcc gcatttggca atgccgccag
    55861 cgtgctggta ggcgatttta tttatacccg cgcgttccag atgatgacca gcctcggttc
    55921 actcaaagtg ctggaagtca tgtcagaagc cgtaaacgtc atcgcagaag gtgaagttct
    55981 gcaactgatg aacgttaacg atccggacat cactgaagaa aactacatgc gcgttatcta
    56041 cagcaagact gcgcgtctgt ttgaggctgc cgcgcagtgt tccgggattc tggctggctg
    56101 tacgccggag gaggagaaag gcctacaaga ttatgggcgc tatctcggca ctgctttcca
    56161 gttgatcgac gatttactcg attacaatgc cgatggcgaa cagttaggta aaaacgtcgg
    56221 cgacgatctg aacgaaggta aaccgacgct gccgctgctg catgcgatgc atcatggcac
    56281 accagaacag gcacagatga ttcgtaccgc catcgaacag ggtaacggtc gccatcttct
    56341 ggaaccggtt ctggaagcaa tgaacgcttg tggatctctt gaatggacgc gtcagcgtgc
    56401 cgaggaagaa gcagacaaag ccatcgcagc gttacaggtg ctcccggaca ccccgtggag
    56461 agaagcactt atcggcctcg cgcacatcgc tgttcaacgc gatcgttaat cccctcccct
    56521 catcccgcgc agtgcgcggg atgattccag taaattccat aaaacactta ttcagctcta
    56581 taactcctga aaaacagggc tgtgtatctt tatatattct gaatattcac actctttaca
    56641 ggaacttttt agagcaatag gccatcagga gtatagtgat gctcgacaga aacagaagaa
    56701 gtattctgaa tgaaagcgac taatttaagg agtgaggaaa gatggaaagt aatttcattg
    56761 actggcatcc cgctgacatc attgcaggtt tgcgcaagaa gggaacgtca atggcggcgg
    56821 agtctcgcag aaatggtttg agttcctcaa cgctggcgaa cgcattatca cgcccatggc
    56881 cgaaaggaga gatgattatt gcgaaagccc tgggaactga cccctgggtt atctggccat
    56941 cacgctacca tgatccgcag acccatgagt ttatcgacag aacgcagttg atgcgtagct
    57001 acactaaacc gaaaaaatga gtggtctggc ggtagccccg cgaacggggc tgccagctct
    57061 cagacaatta ctcgcctttc acacgctcaa tatttgcacc taaagcgcgt agtttgtctt
    57121 caatgcgttc gtagccacga tcgatgtgat aaatacgatc aaccaccgtc gtcccttccg
    57181 caatacagcc agccagcacc aggcttgctg atgcacgcag atcggttgcc ataacctgtg
    57241 cgccagaaag tttttcaaca ccgtgacaaa taacggtatt gctttcgatt tcggcgtgcg
    57301 cgcccatacg gctcagctct ggcacatgca taaagcggtt ttcaaagacc gtttcggtga
    57361 tgaatccggt cccttctgcc accaggttca acagcgtgaa ctgggcctgc atatcggtcg
    57421 ggaatgccgg atgcggcgcg gtacgtacgt taacagcctt cggacgtttg ccatgcatat
    57481 ccaggctaat ccagtcttcg ccgacttcga tgtccgctcc agcgtcacgc agtttcgcca
    57541 gcacggcgtc cagagtatct ggctgcgcgt tacggcagat aattttgccg cgagagatcg
    57601 ccgccgccac caggaaagta ccggtttcga tacgatccgg cagcacgcga tagacaccgc
    57661 cgcctaaacg ttccacacct tcgatgacga tacgatcggt gccctgaccg ctaattttcg
    57721 cacccagcgt aatcaggaag ttcgcggtat cgacgatttc cggttcacgc gctgcgtttt
    57781 caataatcgt ggtgccttcc gccagggttg cagcacacat gatggtcacc gttgcgccaa
    57841 cgctgacttt atccatcacg atatgtgcgc ctttcagacg accatcgacg gaagctttaa
    57901 cgtaaccttc ttccagtttg atggtcgcgc ctaattgttc gaggccagaa atgtgtagat
    57961 caaccggacg tgcgccgatc gtacaaccgc caggcagtga aacttgcccc tgaccaaagc
    58021 gcgctaccag cggccccagc gcccagatag aagcacgcat ggttttaacc agatcgtaag
    58081 gtgcgcagaa tacattaacg tcgcgggcat caatatgcac agaaccatta cgttctactt
    58141 tcgcacccag ctggcttagc agcttcattg atgtatcgac gtcttttagt ttcgggacgt
    58201 tctggatctc taccggttct tccgccagta gtgcggcaaa aaggataggc agagcagcat
    58261 ttttagcgcc ggaaattgtg acttcgccct ggagcttcgt tggcccctga acacgaaatt
    58321 tatccattta gtttgttctc agttaacaat tcatatccgc taccggcgaa tcgcccatag
    58381 ctcaaaagcc gttcagtttg cgatcgcgcg cccactccgc aggggtatac gctttgatcg
    58441 acacagcatg aatgcggtta tccgcaatat attccatcag cgggccatag accgtctgct
    58501 gttttttaac ccgactcatg ccgtcaaaca actcacccac ggcaataacc tgaaagtggc
    58561 tgccatcgcc ggaaacgtgg acttcctgga gggagagagc gttcatcaac acgctctgaa
    58621 tttcattatt ttccatggga tcttcaatca tcagttaata aatcagcgaa acatcttaga
    58681 gcaaagttgc gctggcataa ataagcaaaa agcctcgctg ataaatcaga caaggctcga
    58741 cttgcaggca ggtttgccgg acaggcggtt aacgccatat ccggcctgaa aaaatttaac
    58801 gaggcagaac atcagcaggc aaattataca atttcgccag ggtatacact ttgtcgttta
    58861 ccccctgaag cgtcacattg ttgccctgct ttttcgccag atcgataaga tggagcagca
    58921 gtgccagtcc acccgtatcc acgcgagaca cacggctaag atcgatgctg gtaatcccct
    58981 tcaccgcttc ctcacgtatt tcccaaagcg gtagcaaaac gtcctgatcc agctctccgg
    59041 ataacgccag cgtgtcaccc gtctgcatcc agctcagtga ctcgctcatt attttttctc
    59101 ttccagagtg attttctgtt gagaaatcga tttcagttgc gcagtcaggc cgtcgatacc
    59161 tttggtacgc agcagcgttc cccactcgtt ttgtttggtg gtgatcatac tgacgccttc
    59221 agcaatcatg tcgtaagcct gccagttgcc cgtctgggag tttttacgcc actggaagtc
    59281 cagacgcacc ggcgggcggc cattcgggtc aataatggta acgcgaatcg gcacaatggt
    59341 tttatcaccc agcggctgtt ctggcgcaat ctgataggtt tgaccgtgat acatcgccag
    59401 cgcctgaccg taagcctgct tcaggtactc acggaaagcg gcaaagtaag catcacgttg
    59461 agctggggtc gcactcttgt aatactggcc cagcaccagc gcaccggcgt atttcacctg
    59521 tacgtatggc aacagttcct gatcaacaat ggtacgcaga taatccgggt tggcccgaat
    59581 ttgcggttgc tcattcttca ggcgatcgaa cgttttctgc gccgcctcgt ccatcagctt
    59641 atacggattg gtctggtctg ccgcggttgc cgcactcagc ggtgcaatca ccagcaaagc
    59701 gaccatcatt aaacgtttaa acatgcgtcg gttctcctga aattatttcg ttgtacccac
    59761 aggttcagtg gtttcattat tacctggcgc agcagctggc gcatcgccac tattcttatt
    59821 gtcatcgcct ttactaccgt aaaggaactg accaatgaga tcttccagca ccatcgcaga
    59881 cttggtgtcc tgaattgtat cgccatcctt caggatagca gtccccagtt ccgggtcttc
    59941 aaaaccgacg tttaatgcca gatattgttc ccccagcagg ccggaagtac gaatgctcag
    60001 cgaactggta tcaggaatgt ggttataacg ttgttcaatt tccagcgtta cgcgcggcag
    60061 ataggttttc gggtccagcg taatatccgc cacccggccc acaacaacgc caccaatgct
    60121 gaccggagag cgggctttca ggccgccaat gttatcgaac gtcgcataaa gcgtataggt
    60181 cggttcagta cgtatagacg tcacgttcgc tgccttcagg caaacaaaca gcgccgcaag
    60241 cagtgctgct aataaaaaga tacccaccca aatttcattt tttttcgttt gcatgaactc
    60301 aattcccaaa catcaatgcg gtcagcacaa aatccagccc cagaacagcc agagacgagt
    60361 ggacaacggt gcgagtggtt gcccggctaa tcccggcaga cgtcgggatg gcgtcgtagc
    60421 cgttaaacaa cgaaatccac gtcaccgtga tggcgaacac cacgctctta atcagacagt
    60481 tgacgagatc catacgccag tcgacggcat tttgcattgc cgaccagaag aacccactat
    60541 caatgccttt ccaactgacg ccgaccagcg atccgcccca gatccccacg gcgacgaaga
    60601 taaccgtcaa cagtggtaat gaaataactc cagcccagaa acggggagaa ataacccgac
    60661 gcagcggatc caccgccatc atctccatac tggagagttg ctctgtagcg cgcatcaggc
    60721 cgatttctgc ggttagcgcc gaaccagcac gcccggcaaa caacaacgcg gcaaccaccg
    60781 gccccagttc acgcagtagc gataacgcca ccagcatacc cagactggtt tccgcactat
    60841 aagtggtcag aaccagataa ccttgcagcc ccaacaccat tccgatgaac acgccagaaa
    60901 caacaataat cagcatcgac aggacgccga cattatagag ctggcgcacc agcagcggtg
    60961 catgtttgcg aaattccggt ttgccgacca gcgcattgaa taacattaac ccggcccgcc
    61021 cgaacgttct cagggtttta atccctttat gtccgagcga cgccagcgca tttaacagca
    61081 tgagtggctt aactccctgg taaaagatca gcgtgataat cgccggcagg atagcggaac
    61141 ggaacaggcc cgtcagctat cccgtccaga aactgacgta cgcgcggatc aggattcgcc
    61201 tgcaacgcct gggcactacc atgagcgaca atttttttgt ccgccaggat ccaggcgtga
    61261 tccgcaatac ttaacacttc cggcacatcg tgagaaacca ccacacaagt cacgcccagc
    61321 gcgctgttca gctcagaaat cagcttcacc agcacgccca tggtaatggg atcttgccca
    61381 acaaagggct catcaaacat gatgagatcc ggctccagcg caatcgcacg tgccagcgct
    61441 gcacgccgcg ccatcccacc ggaaagttca gaaggcataa gtttagccgc tccacgcagc
    61501 cccacggcct ccagcttcat catcaccgta ctatgcaaca atggcgcggg aagttgggta
    61561 tgttcccgca gtggataggc gacgttgtca aatacgttca tatcagtgaa caacgccccg
    61621 gactgaaata acatgctcat ccgtttgcgc actgtataca ggcgcgaacg agacatcgcc
    61681 ggaatattct caccatcgaa aagaatctca ccatgatctg gtgcgatttg cccgccaatc
    61741 agacggagta gcgtcgtttt accgatgccc gatggcccca tgatcgccgt gatcttccct
    61801 cgcggcacgg tcagggaaat attatcgaag atgcagcgat tgccacgcgt aaaactgaca
    61861 tcgcgcatat cgactaaatt cgccacagac tgctccataa ttcacccttc gtcttgcgtt
    61921 gattttctaa gcatggcgct caatttaacc ttgaacccaa catatttaca gaatattacc
    61981 tgccgtggtt agcgaaagct ggcatttgtt ttacttttta gccgcataaa gtcaaaatta
    62041 agaatctgtt acggctttct gaaaatcttc agcggaccgg cgagtatacc tgaagaaagg
    62101 acgttagatg cttttagcta cggcactgtt aattgttggt ttacttttgg tcgtttacag
    62161 tgccgaccgc ctggtttttg ccgcgtctat tctttgccga acctttggca tcccgccgtt
    62221 gatcatcggc atgacggtgg tcagtattgg tacatcgtta ccagaaatca tcgtctcgct
    62281 tgccgcgtct ttgcacgaac aacgcgattt agccgttggt acagccctcg gctcaaacat
    62341 tatcaatata ttgctgatcc tcggtctggc tgcgctggtt cgtcctttta ccgtccattc
    62401 tgatgttcta cgccgtgaat tacccttaat gttgttggtc agcgtggtgg ccggttccgt
    62461 actctatgac ggacaactta gtcgcagcga tggtatcttt ctcctctttc tggctgtgct
    62521 atggctgctg ttcattgtta aacttgcacg tcaggctgaa cgtcagggga ctgacagcct
    62581 gaccagagag cagcttgcag agctgccgcg tgaaggtgga ttgcccgtcg catttttatg
    62641 gctcggcatc gcactgatca ttatgccagt ggccacgcgg atggtagttg ataacgccac
    62701 ggtgctggcg aattactttg ccatcagcga gttgacgatg ggtctgacgg caattgctat
    62761 cggaaccagc ctgccggaac tggcaaccgc aatagcaggg gttcgcaaag gtgaaaacga
    62821 cattgcggtc ggaaatatca ttggcgcaaa catttttaat attgtcatcg tgttgggttt
    62881 acccgcgctg ataacgccag gagagattga tccactggcg tacagtcgtg actacagcgt
    62941 gatgttgctg gtgagcatta tttttgcgtt gctgtgctgg cggcgctccc cgcaaccggg
    63001 ccgtggtgta ggggtattat taactggcgg atttatcgta tggctggcga tgttgtactg
    63061 gttatcgcca atactcgttg aataactgga aacgcattat gtcgcacgta gagttacaac
    63121 cgggttttga ctttcagcaa gcaggtaaag aagtcctggc gattgaacgt gaatgcctgg
    63181 cggagcttga tcaatacatc aatcagaatt tcacgcttgc ctgtgaaaag atgttctggt
    63241 gtaaagggaa agttgtcgtc atggggatgg ggaaatcggg gcacatcggg cgcaaaatgg
    63301 cagcaacatt tgccagcact ggtacacctt catttttcgt ccatcctggt gaagccgcgc
    63361 atggtgattt aggcatggtc accccgcagg atgtggtgat tgctatctct aactcaggtg
    63421 aatccagcga aatcacggcc ttaattccag tgcttaagcg tcttcacgta ccgttaatct
    63481 gcatcaccgg tcgcccggag agcagcatgg cgcgcgccgc agatgtgcat ctgtgtgtta
    63541 aagtagcgaa agaagcctgt ccgttagggc tggcaccgac cagcagcaca accgccacgc
    63601 tggttatggg cgatgccctc gctgtcgcgc tgttaaaagc acgcggcttt actgctgaag
    63661 attttgcgct ctcacaccca ggcggcgcac tgggtcgtaa acttctgctg cgcgtaaacg
    63721 atattatgca tacgggcgat gagatcccgc atgttaagaa aacggccagt ctgcgtgacg
    63781 cattgctgga agttacccgc aaaaatcttg gtatgactgt catttgcgat gacaatatga
    63841 tgattgaagg catctttacc gacggtgatt tacgccgtgt cttcgatatg ggcgtggatg
    63901 ttcgtcagtt aagtattgcc gatgtgatga cgccgggggg aatacgcgtg cgcccaggca
    63961 ttctggccgt tgaggcactg aacttaatgc agtcccgcca tatcacctcc gtgatggttg
    64021 ccgatggcga ccatttactc ggtgtgttac atatgcatga tttactgcgt gcaggcgtag
    64081 tgtaaagatt caaggataaa caacaatgag caaagcaggt gcgtcgcttg cgacctgtta
    64141 cggccctgtc agcgccgacg ttatggcaaa agcagagaac attcgtctgc tgatcctcga
    64201 cgttgacggc gtactgtcag atggcctgat ttatatgggc aataacggcg aagagctgaa
    64261 agcgttcaat gttcgtgacg gttatggcat tcgttgtgcg ctcacctctg atattgaagt
    64321 cgctatcatt accgggcgaa aggctaaact ggtagaagat cgttgtgcca cattggggat
    64381 cactcacttg tatcaggggc agtcaaacaa actgatcgcc tttagcgatc tgctggaaaa
    64441 actggcgatt gccccggaaa atgtggctta tgtcggcgat gatctcatcg actggccggt
    64501 aatggaaaaa gtgggtttaa gcgtcgccgt ggccgatgcg catccactgt tgatcccgcg
    64561 cgccgattac gtaacgcgca ttgctggcgg tcgtggcgca gtgcgagaag tttgcgactt
    64621 attactcctg gcgcagggca aactggatga agccaaaggg caatcgatat gagtaaagcc
    64681 agacgttggg ttatcattgt gctatcactg gcggttctgg tgatgatcgg cattaatatg
    64741 gccgaaaaag acgataccgc ccaggtggtc gtcaacaaca atgatcccac ctataaaagc
    64801 gagcatacgg acacgctcgt ctataaccca gaaggggcac taagctatcg attgattgct
    64861 caacacgttg aatattattc cgatcaggcc gtttcgtggt ttacgcagcc ggtacttacc
    64921 acgtttgata aggataaaat cccgacatgg tccgtaaaag cagataaagc caagctgacc
    64981 aatgaccgga tgctctattt atatggacac gttgaagtca atgcactcgt gccggactct
    65041 caacttcgca gaatcacgac ggataacgcg cagatcaatc tggtgacgca ggatgttacc
    65101 tctgaagacc tcgtcacgtt atacggaaca acatttaact ccagcggtct gaaaatgcgc
    65161 ggcaacttac gcagcaagaa cgccgagctg attgaaaagg ttagaacatc ctatgaaatt
    65221 caaaacaaac aaactcagcc ttaatcttgt gcttgccagc tcacttctgg ccgccagcat
    65281 tccggcattt gccgtaaccg gagacactga tcagccgatc cacattgaat cggaccagca
    65341 atctcttgat atgcaaggca acgtggttac ctttaccggt aatgttatcg tcacccaggg
    65401 caccatcaaa attaatgccg acaaagtggt cgttacccgt ccgggcggcg aacaaggtaa
    65461 agaagtgatt gacggctacg gtaaaccggc aacgttctac cagatgcagg acaacggtaa
    65521 acccgttgaa ggtcacgctt cccagatgca ctacgaactg gcaaaagatt ttgtcgttct
    65581 gacgggtaat gcttatctgc agcaggtcga tagcaacatt aagggcgata agatcactta
    65641 cctggtgaaa gagcagaaaa tgcaggcttt cagcgacaaa ggcaagcgcg taaccaccgt
    65701 tctggtgccg tcgcagttgc aggacaaaaa caataaaggc cagaccccgg cacagaagaa
    65761 gggtaattaa ttcgttatgg caacattaac tgcaaagaac cttgcaaaag cctataaagg
    65821 ccgtcgcgtg gtagaagacg tcagcctgac cgtcaactcc ggggaaattg tcggtctgct
    65881 ggggccaaac ggtgccggta agaccaccac tttctacatg gttgttggca ttgtgccgcg
    65941 cgatgcgggc aacatcatta ttgatgatga cgatatcagt ctgctgcctc tgcatgcacg
    66001 cgcgcgccgc ggtatcggct atctgccgca ggaagcctcc attttccgtc gcctcagcgt
    66061 ttacgataac ctgatggcgg tactgcaaat tcgtgacgac ttgtctgctg aacaacgtga
    66121 agaccgtgcg aacgagctga tggaagagtt tcacattgag cacctgcgtg acagcatggg
    66181 gcagtcactc tccgggggtg aacgtcgccg tgtagaaatt gcccgcgcac tggctgcgaa
    66241 tccgaaattt attctgctcg acgaaccgtt tgccggggtt gacccgatct cggttatcga
    66301 cattaaacgc atcattgagc acctgcgcga cagcggcctg ggcgtactga tcactgacca
    66361 caacgtgcgt gaaacactgg cggtttgtga acgcgcttat atcgtcagtc aggggcattt
    66421 gatcgcccac ggcacgccta cagaaatctt acaagacgaa cacgttaagc gtgtatacct
    66481 tggggaagac ttcagactct gatagggtag aagtttgcga cgttttagca ggagagtacg
    66541 attctgaaca tgaagcaagg tttgcaactc aggcttagcc aacaactggc gatgacgcca
    66601 cagctccaac aggcaattcg tctgttgcag ttgtcgacgc tggaacttca gcaagagcta
    66661 cagcaggcgc tggagagcaa tccgctgctt gagcaaatcg acactcatga agaaatcgac
    66721 acccgcgaaa cgcaagacag tgaaacactg gacaccgccg acgcgctcga acaaaaagag
    66781 atgccggaag agctgccgct cgatgccagt tgggacacca tttacaccgc tggtacacca
    66841 tccggcacca gcggtgacta cattgatgac gagctgccgg tctatcaggg cgaaacgacg
    66901 cagaccttac aggattacct gatgtggcag gtcgagttga caccgttttc cgacactgac
    66961 cgcgcgattg ctacctctat cgtcgatgcc gttgatgaca ccggttatct gactgtcccg
    67021 ctggaagata ttctcgaaag tatgggcgat gaagagattg acatcgacga agttgaagcc
    67081 gtccttaagc ggatccaacg gtttgatcca gtcggtgtgg cggcaaaaga tctgcgtgac
    67141 tgcctgctga tccaactctc ccaattcgat aagaccacgc catggctgga agaggccaga
    67201 ctgatcatta gcgatcatct cgatctatta gccaatcacg acttccgcac tttaatgcgc
    67261 gtcacgcgtc tgaaagaaga tgtgctgaaa gaagccgtca atctgatcca gtcgctcgat
    67321 ccgcgccccg ggcagtcgat ccagactggc gaacctgagt atgtcattcc agatgtgctg
    67381 gtgcgtaagc ataacggcca ctggacggta gaactcaaca gtgacagcat tccgcgtctg
    67441 caaatcaacc agcactacgc ctcgatgtgc aataacgcgc gcaatgatgg tgatagccag
    67501 tttatccgca gcaatctgca ggatgccaaa tggttgatca agagtctgga aagccgtaac
    67561 gatacgctac tgcgcgtgag tcgctgtatc gttgaacagc agcaagcctt ctttgagcaa
    67621 ggtgaagaat atatgaaacc gatggtactg gccgatatcg cccaggctgt cgaaatgcat
    67681 gaatcgacga tatctcgcgt gaccacgcaa aaatacctgc atagtccacg aggcattttt
    67741 gaactgaaat atttcttttc cagtcacgtc aatactgaag gcgggggtga agcctcttcc
    67801 acagcgattc gtgcgctggt gaagaaatta atcgcggcgg aaaacccagc gaaaccgttg
    67861 agcgacagca agttaacctc tttgctgtcg gaacaaggta tcatggtggc acgccgcact
    67921 gttgcgaagt accgagagtc tttatccatt ccgccgtcaa accagcgtaa acagctcgtt
    67981 tgacccaacc gataaggaag acactatgca gctcaacatt accggaaata acgtcgagat
    68041 caccgaggca ctgcgcgaat ttgttacagc caaatttgcc aaacttgagc aatattttga
    68101 ccgaatcaac caggtctatg ttgttctgaa agtggagaaa gtcacccaca cctcagatgc
    68161 aacactgcat gtaaacggtg gtgaaattca tgccagcgcg gaaggtcagg acatgtacgc
    68221 tgccattgat ggcttaattg ataagctggc acgccagttg accaaacata aagataaact
    68281 gaaacaacac taattgtccg ggcaattagc atgtgcatgg cggcctgttg tgcggcacaa
    68341 cgggccattt gtacggttaa tgctccgaac ctgttccact gtttgagtgg gcaggttctt
    68401 aggtgaaatt atgacaaata atgatacaac tctacagctt agcagtgttc ttaacaggga
    68461 atgtacgcga agccgcgtcc actgccagag caaaaaacgc gccctggaaa tcatcagcga
    68521 gctggcggcg aaacaactta gcctggcgcc tcaggtggtt tttgaagcta tcctgacgcg
    68581 ggaaaaaatg ggcagtaccg gtatcggcaa tggtattgcc attccgcatg gcaaactgga
    68641 agaagatact ctgcgtgccg ttggcgtttt cgttcagctc gaaacaccta tagctttcga
    68701 tgccatcgac aaccaaccgg tggacttact ttttgccctg ctggtgccgg cagaccaaac
    68761 taaaacgcac ctgcatactc tgtcgctggt ggcgaaacgt ctggcggaca aaaccatctg
    68821 ccgccgttta cgcgcagccc agagcgatga agagctgtat caaatcatta cggataccga
    68881 aggtactccg gatgaagcgt agttattcgg taatgtctct tttagacgtt gtgaggagaa
    68941 acagtacatg gtactgatga tcgtcagcgg acgttcaggt tcaggtaaat ctgtcgccct
    69001 gcgtgcgctg gaagatatgg gtttttactg cgtggataac cttcccgtag tgttgttacc
    69061 cgatctggct cgaactctgg ccgatcgaga gatttctgcc gccgtcagca ttgatgttcg
    69121 taatatgccg gagtcaccag aaatattcga acaggcgatg agtaacctgc ctgacgcttt
    69181 ctcaccgcaa ctactgttcc tggatgccga ccgtaatacc ttaattcgtc gttacagtga
    69241 cacgcgccga ctgcatccgc tttccagcaa aaacctgtcg ctggaaagtg ctatcgacaa
    69301 agaaagcgat ttgctggagc ctctgcgttc gcgagcggat ctgattgtcg atacctcaga
    69361 aatgtccgtt cacgagctgg cagaaatgct gcgtacccgt ctgttgggta aacgtgaacg
    69421 tgaactgacc atggtctttg agtctttcgg cttcaaacac ggtatcccta tcgatgcaga
    69481 ttacgtcttt gacgtgcgct tcttgccgaa cccacactgg gatccgaaac tgcgtccaat
    69541 gacaggtctt gataaacctg tcgccgcgtt cctcgaccgc cacacagaag tacacaattt
    69601 tatctaccag acgcgaagct atcttgagct atggttacct atgctggaaa ccaacaaccg
    69661 tagctacctg acggtcgcca ttggttgtac cggcgggaag caccgttcgg tgtatattgc
    69721 agagcaactg gcagactact tccgctcgcg cggtaaaaac gtccagtcac gccatcggac
    69781 gctggaaaaa cgtaaaccat gaccgtcaag caaactgttg aaattacaaa caagctgggc
    69841 atgcatgccc ggcctgcaat gaagctgttt gaattaatgc agggttttga cgctgaagtg
    69901 ctgttacgta atgacgaagg caccgaggct gaagccaaca gcgttattgc gctgctgatg
    69961 ttggattctg ccaaaggacg gcagattgaa gttgaagcga ccggtccaca ggaagaggaa
    70021 gcactggccg ccgttatcgc cctctttaac tctggttttg atgaagatta atcttcatca
    70081 ctttgacatt caaatccctt caagctcccc cggcaataag aaaagcgcgt actgaaatcg
    70141 ttatcaatca acgtcgattg tacatttcgt gcgcttttta ctttcagaag aaccttaaga
    70201 aaaccttaag aagcattgtt tagatttcgt ttaagttaat cgaccatact ggagatcgtc
    70261 agaaaatatt tccaggagat ggcatgattc gcttatctga acaaagtccc ctgggcaccg
    70321 gaagacatcg gaaatgttat gcgcatccgg aagatgccca acgctgtatc aagattgtct
    70381 accatcgtgg cgatggtggc gataaagaga tccgccgtga gttaaagtac tacgcgcatc
    70441 ttggtcgccg gttaaaagac tggagtggaa taccgcgcta tcacggtacc gttgagacgg
    70501 attgcggaac cggttatgtc tacgatgtga ttgccgattt cgacggcaag ccttccatta
    70561 cgctgaccga atttgcagaa caatgccgtt acgaagaaga cattgcacaa ctgcgccagt
    70621 tactgaaaca gctgaagcgt tatttgcagg ataaccgtat cgtgacgatg tcgctgaagc
    70681 cgcagaatat cctctgtcac cgcatcagtg agtcagaggt tatccccgtc gtctgcgaca
    70741 acattggtga aagcacattg attccactgg cgacctggtc gaagtggtgt tgtctgcgta
    70801 agcaagagcg gttatggaaa cgatttatcg cccaaccggc gctggctatt gccctgcaga
    70861 aagatctgca acctcgtgag agcaaaacgc tggccctcac ttcgcgcgaa gcttaatcaa
    70921 gctggtgttg ttgcataaac ggctcaccgc ctaactgata catctgccgt aaaatccacg
    70981 cctgacggct acgcacatag cccgatggcg cggagacttt gaaacgaagt ggattaggta
    71041 atacagctgc cagtaatgca gcttccgacc gggtaagttt gctcgcgggt ttgtggaaat
    71101 aacgttgtgc cgcagcttcg acgccaaaca caccgtcgcc aaattcggcg atattcaggt
    71161 aaaccgtcag gatacgcttt ttgctccaga ctgtttctat ccccagcgtt aatccggctt
    71221 ccagcccttt tcgaacccag ctacgcccat cccataaaaa gagatttttg gctgtctgct
    71281 gagaaatcgt tgaagcaccg cgaatacggt tttcattgcg ctcgttgtgc gccagggctt
    71341 gctcaatgga agcgacatca aagccccagt gctcaggaaa tttctgatct tctgcggcaa
    71401 tcaccgccag tcccatccac ggcgagattt gatccatact gacccagtca gaatgtgcca
    71461 cgtaacgaaa attgccatgc agccaggcgc tgacttgccg ctcgaccatt accgctgaga
    71521 aaggaacagg cgcaacgcta aacaacgcga tgcccccgcc ccagaaaatg gcgaggacaa
    71581 ccattaaccg cagaagaaaa cggcgaacga aactaaacac cgttaagcgg cttttactca
    71641 ttcagccaga accagcacgc gggaaaccag cttatcaatg ccgctcgccg cttctgcaat
    71701 gttctgcgcc agcatatatg ccggggtggt gacaatctta ttgtcttcat caaccacgat
    71761 atcatcgaca ggacacggca catgctccgc gcccatctct tccagcactt ctgcggtatc
    71821 gatatcagta ccgatggtca aacgtagcgg gaaatcgaaa attttcggca gtatcgccgg
    71881 tgcaatacac ataaaaccaa gcggttttcc ggcctgatgc atcgcttgtg ccagcgcctt
    71941 taattcacgg tcaacggtgc attcgctacc aagactggca aaattgctta aattcttcgc
    72001 cgcgccaaaa ccccccggca caatcaacgc atccagttca gcggcatcgg cctgggccag
    72061 aggacggatt tcaccgcgcg ttattcgtgc cgcttcaatc agcacattgc gcgtttccgt
    72121 catcgcttca ccagttaaat ggttgataac atcaacctgc tgcttatccg gtgcaaagca
    72181 aaccgcctgc gcaccgctgc gtgaaatagc taacaacgtc aataccgctt catgaatttc
    72241 agaaccgtca tagacgccgc atccgctcag aattacgcca attttcttca ttgtgatctt
    72301 cctttcgcaa ttgactgaaa cacattaatt tttttaataa aaatgctacg cat
//
LOCUS       DAPOXO010000012        72300 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPOXO010000012 DAPOXO010000000
VERSION     DAPOXO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 72300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72300
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.012"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..244)
                     /locus_tag="ROH59_001048"
     CDS             complement(<1..244)
                     /locus_tag="ROH59_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HDX4803566.1"
                     /translation="MAKKVSKFFRIGVEGDTCDGRVISAQDIQEMAETFDPRVYGCRI
                     NLEHLRGILPDGIFKRYGDVAELKAEKIDDDSALKGK"
     gene            418..2190
                     /locus_tag="ROH59_001049"
     CDS             418..2190
                     /locus_tag="ROH59_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HDX4803567.1"
                     /translation="MTITTDTTLLHDPRRQAALLYWQGFSVPQIAAMLQIKRPTVQSW
                     KQRDGWDSVAPISRVEMSLEARLTQLIIKPQKTGGDFKEIDLLGRQIERLARVNRYSQ
                     TGNEADLNPNVANRNKGGRRKPKKNFFSDEAIEKLEQIFFEQSFEYQLHWYRAGLEHR
                     IRDILKSRQIGATFYFSREALLRALKTGHNQIFLSASKTQAYVFREYIIAFARLVDVD
                     LTGDPIVLGNNGAKLIFLGTNSNTAQSHNGDLYVDEIFWIPNFQVLRKVASGMASQSH
                     LRSTYFSTPSTLAHDAYPFWSGELFNRGRASAAERVEIDVSHNALAGGLLCADGQWRQ
                     IVTIEDALKGGCTLFDIEQLKRENSADDFKNLFMCEFVDDKASVFPFEELQRCMVDTL
                     EEWEDYAPFAANPFGSRPVWIGYDPSHRGDSAGCVVLAPPVVAGGKFRILERHQWKGM
                     DFATQAESIRKLTEKYNVEYIGIDATGLGVGVFQLVRSFYPAARDIRYTPEMKTAMVL
                     KAKDVIRRGCLEYDVSATDITSSFMAIRKTMTSSGRSATYEASRSEEASHADLAWATM
                     HALLNEPLTAGISTPLTSTILEFY"
     gene            2190..3224
                     /locus_tag="ROH59_001050"
     CDS             2190..3224
                     /locus_tag="ROH59_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001752368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDX4803568.1"
                     /translation="MSKKKGKTPQPAAKTMTASGPKMEAFTFGEPVPVLDRRDILDYV
                     ECISNGRWYEPPISFTGLAKSLRAAVHHSSPIYVKRNILASTFIPHPWLSQQDFSRFV
                     LDFLVFGNAFLEKRYSTTGKVIRLETSPAKYTRRGVEEDVYWWVPSFNEPTAFAPGSV
                     FHLLEPDINQELYGLPEYLSALNSAWLNESATLFRRKYYENGAHAGYIMYVTDAVQDR
                     NDIEMLRENMVKSKGRNNFKNLFLYAPQGKADGIKIIPLSEVATKDDFFNIKKASAAD
                     LLDAHRIPFQLMGGKPENVGSLGDIEKVAKVFVRNELIPLQDRIREINGWLGQEVIRF
                     KNYSLDTDNG"
     gene            3640..4713
                     /locus_tag="ROH59_001051"
     CDS             3640..4713
                     /locus_tag="ROH59_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HDX4803569.1"
                     /translation="MDNKIVEIETNKLDFDPKNPRFFRLNDASNAATVIEEMLDDESV
                     HDLMLSIGQQGYFPGEPLLAVKSNGNYIVVEGNRRLAAVKLLNGDLLPPKRKLKGVQE
                     IIDDTTNKPKKLPCIIYENREDVLRYIGYRHITGVKEWDSLSKAKYLKELCDTFYSHE
                     PKEIVLKNLAREIGSKPHYVATLLTALNLYEVAHDHEFFNLPMKASDVEFSYITTALG
                     YSKITNWLGLQDKKDFLDPNLNEENLKRLFSWFFVPDQQGRTIIGESRRIKDIAAVVE
                     KPEAIEILMKSSNLDEAYLYTSGEREALDKALNAASVKLRVVWDMLLKAKELTLEHEE
                     AASEIFEMSKNIRNQIRSKREDD"
     gene            4718..5743
                     /locus_tag="ROH59_001052"
     CDS             4718..5743
                     /locus_tag="ROH59_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803570.1"
                     /translation="MITNLDSMPSNEPYLWADYIEILALTNIDRSFSRGDLYSTLQAQ
                     PEAVLAETDEAEEEGVYDVDDENDTPVRKRTKRSVSRAYTDRKWSYAIGFIRQRIDLF
                     GDSYPFTLSEDNDTVELRDISEKPLEHLERLYLALLICANIKYVNIMSRREITRSFEL
                     ISLPIFESLMPSGSIIKACWASGGQAAPYTGTLYNKFKSIASDIRCTANFKERDFSRG
                     NSGDGGLDIIAWHPMGDQRDAIPISFVQCGCSQEEWEAKQLEASPAMLYSKFPVAHRW
                     ATYYFLPQDLRWIDGEWAHKNKLGDAIFVDRLRLINLTRASDNIDHSQNISYLDIILD
                     PSSAIAA"
     gene            complement(5740..6678)
                     /locus_tag="ROH59_001053"
     CDS             complement(5740..6678)
                     /locus_tag="ROH59_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDX4803571.1"
                     /translation="MPTVVSLFSGCGGSDAGVLNAGFNVLMANDILPYARDVYLENHP
                     ETDYILGDISGLQSFPSAELLIGCYPCQGFSQGGARKADRKINTLYLEFARALSKIKP
                     KAFIVENVSGMVRRNFEHLLKDQFKVFEEAGYTVSSQILNASHYGVSQDRKRIFIVGI
                     RKDYGITYKFPKPTHGDGLTPYSTIRDAIGHMPVWPVGEFYDADFHWYYLSRNRRQDW
                     DQISKTIVANPRHMPLHPISPTLEKLGPDKWQFTSDAPARRFSYREAAILQGFGDLIF
                     PETERASINMKYTVVGNAVPPPLFEAVARNLPDLWD"
     gene            complement(6921..7127)
                     /locus_tag="ROH59_001054"
     CDS             complement(6921..7127)
                     /locus_tag="ROH59_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803572.1"
                     /translation="MHRIPGEIPHHKTKNIKLMAIVQRLQRIMVNENLTPDELVGCAE
                     IVRDNYGRFNHIGQSRVAPPQRRR"
     gene            complement(7127..7579)
                     /locus_tag="ROH59_001055"
     CDS             complement(7127..7579)
                     /locus_tag="ROH59_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HDX4803573.1"
                     /translation="MAKIHEVKLHAKYFDLVLEGKKRAEFRKNDRNYERGDTLILYEW
                     VQGVYTGRNVEARITDVTDLSDWLEDYVLLSIELLNTGAYEIVNWKELSERGLVFRIN
                     HEIMHQLGLAVMYEPETGMSGGAMVATDGAWNYSDEQMERAQQNGWLG"
     gene            complement(7579..9864)
                     /locus_tag="ROH59_001056"
     CDS             complement(7579..9864)
                     /locus_tag="ROH59_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HDX4803574.1"
                     /translation="MAVKASGRFVPPSAFAAGTGKMFTGAYAWNAPREAVGRERPLTR
                     DEMRQVQGVLSTINRLPYFLRSLFTSRYDYIRRNKSPVHGFYFLTSTFQRRLWPRIER
                     VNQRHEMNTDASLLFLAERDHYARLPGMNDKELKKFAARISSQLFMMYEELCDAWVDA
                     HGEKESLFTDEAQAHLYGHVAGAARAFNISPLYWRKYRKGQMTTRQAYSAIARLFNDE
                     WWISQLKGQRMRWHEALLIAVGEVNKDRSPYASKHAIRDVRARRQANLEFLKSCDLEN
                     RETGERIDLISKVMGSISNPEIRRMELMNTIAGIERYAAAEGDVGMFITLTAPSKYHP
                     TRQVGKGESKTVQLNHGWNDEAFNPKDAQRYLCRIWSLMRTAFKDNDLQVYGLRVVEP
                     HHDGTPHWHMMLFCNSRQRNQIIEIMRRYALKEDGDERGAARNRFQAKHLNRGGAAGY
                     IAKYISKNIDGYALDGQLDNDTGRPLKDTAAAVTAWASTWRIPQFKTVGLPTMGAYRE
                     LRKLPRGVSIADEFDERVEAARAAADSGDFALYISAQGGANVPRDCQTVRVARSPSSD
                     VNEYEEEVERVVGIYAPHLGARHIHITRTTDWRIVPKVPVVEPLTLKSGIAAPRSPVN
                     NCGKLTGSDTSLPAPTPYEHAAAVLNLVDDGVIEWNEPEVVRALRGALKHELRTPNRQ
                     QRNGSPLKPHEIAPSARLTRSERTQITRIRVDLAQNGIRPQRWELEALARGATVNYDG
                     KKFTYPVADEWPGFSTVMEWT"
     gene            complement(9854..10129)
                     /locus_tag="ROH59_001057"
     CDS             complement(9854..10129)
                     /locus_tag="ROH59_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5405 family protein"
                     /protein_id="HDX4803575.1"
                     /translation="MSIRIEIGERYVVTSDSFQFILHEKKRAESGKNAGQEWLAVVGY
                     YPKLSQLVSGLMHHDILTGSAKSFADLNAQVEQLSRRCSEAFGSYGR"
     gene            complement(10126..10350)
                     /locus_tag="ROH59_001058"
     CDS             complement(10126..10350)
                     /locus_tag="ROH59_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDX4803576.1"
                     /translation="MPDNVDFIQEQQAELLERQINAARVKHCGASALVCEECDAPIPA
                     ARRAAYPSATRCVSCQSVFEAKNKHYRRTA"
     gene            complement(10350..10652)
                     /locus_tag="ROH59_001059"
     CDS             complement(10350..10652)
                     /locus_tag="ROH59_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5405 family protein"
                     /protein_id="HDX4803577.1"
                     /translation="MSCSRSVVLLNNALKIAVMKNGDLSLIQLGLDKEKREITESVIA
                     IYQNELNLLSDVVNLLVKRAVFHKQISSVDELTKLTTEIASYCADEFKNLNDKRNW"
     gene            complement(10652..10876)
                     /locus_tag="ROH59_001060"
     CDS             complement(10652..10876)
                     /locus_tag="ROH59_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 family protein"
                     /protein_id="HDX4803578.1"
                     /translation="MHTVSENQCGKYALLLQQARTEAQADAATRFSSHLDAMIRHITK
                     AELSRVEIVELLSQESEKFHNIGLSRGEVL"
     gene            complement(10940..11440)
                     /locus_tag="ROH59_001061"
     CDS             complement(10940..11440)
                     /locus_tag="ROH59_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein B"
                     /protein_id="HDX4803579.1"
                     /translation="MTVMTLNLVEKQPAAMRRIIGKHLAVPRWQDTCDYYNQMMERER
                     LTVCFHAQLKQRHATMRFEEMNDVERERLVCAIDELRGAFSKRRQVGASEYAYISFLT
                     VSQRRTLFMHARLTEKEFNQPYWRINEESCYWRDALFRALRELFSLFEYAPTILTSVK
                     PEQYLH"
     gene            complement(11437..11634)
                     /locus_tag="ROH59_001062"
     CDS             complement(11437..11634)
                     /locus_tag="ROH59_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803580.1"
                     /translation="MAFVDGVVIMSEPRCIAQLLRNESPRAIDFTITHGKGRKGIIIR
                     TKKQSPLKKALTFLKSRRGWK"
     gene            complement(11610..11882)
                     /locus_tag="ROH59_001063"
     CDS             complement(11610..11882)
                     /locus_tag="ROH59_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803581.1"
                     /translation="MEVNDYVIQYPIDAVHTVKFAELLGKPETAVVKMVKENKLPVIE
                     LRDPSKPNARVGEKWVFIPEFNRAVREAFYNRPVEQRDAWLLWMGL"
     gene            12035..12328
                     /locus_tag="ROH59_001064"
     CDS             12035..12328
                     /locus_tag="ROH59_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001192859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4803582.1"
                     /translation="MQTFEKLKAIRKAEGLTQAKFSEISGIALGTVKNYESGHKDPGL
                     SIVMRVTNTPLFKKYTLWLMTGDTSPQAGQIAPALAHIGQKPTESDHSEKQTG"
     gene            12398..13378
                     /locus_tag="ROH59_001065"
     CDS             12398..13378
                     /locus_tag="ROH59_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX4803583.1"
                     /translation="MSIKKLDDGRYEVDIRPRGRDGKRIRRKFERKAEAVAFERYTIA
                     YASQKEWAGQRADRRTLSELLNIWWKYHGQNHEHGTKEFNHLLKTISGIGDIPVSRMS
                     KRALMDYRSMRLRDGISAATINRDMYRLSGMFTKLIQLDEFSGQHPIHGLPPLAEANP
                     EMTFLEKAEIEKLLNVLDGDDLLVALLCLSTGGRWTEVATLKPAQITNCRVTFLKTKN
                     GKKRTVPISEELEKKVKEEASAKLFKVDYEKFCGILRRVKPDIPPNQATHILRHTFAS
                     HFMMNGGNIIALQQILGHASIQQTMAYAHLAPDYLQNAVALNPLKGGVTL"
     gene            complement(13564..14064)
                     /gene="cpxP"
                     /locus_tag="ROH59_001066"
     CDS             complement(13564..14064)
                     /gene="cpxP"
                     /locus_tag="ROH59_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HDX4803584.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            14214..14912
                     /gene="cpxR"
                     /locus_tag="ROH59_001067"
     CDS             14214..14912
                     /gene="cpxR"
                     /locus_tag="ROH59_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HDX4803585.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALSLNPGRQEATFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            14909..16282
                     /gene="cpxA"
                     /locus_tag="ROH59_001068"
     CDS             14909..16282
                     /gene="cpxA"
                     /locus_tag="ROH59_001068"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HDX4803586.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTV
                     NFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(16453..17127)
                     /gene="yiiM"
                     /locus_tag="ROH59_001069"
     CDS             complement(16453..17127)
                     /gene="yiiM"
                     /locus_tag="ROH59_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HDX4803587.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTDLGLEGDEQ
                     AEKKIHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYIGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGLVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSVAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(17276..18259)
                     /gene="kdgT"
                     /locus_tag="ROH59_001070"
     CDS             complement(17276..18259)
                     /gene="kdgT"
                     /locus_tag="ROH59_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HDX4803588.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK"
     gene            complement(18519..19139)
                     /gene="sodA"
                     /locus_tag="ROH59_001071"
     CDS             complement(18519..19139)
                     /gene="sodA"
                     /locus_tag="ROH59_001071"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HDX4803589.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQAYVNNANAALE
                     SLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVQKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPIVGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            19424..20458
                     /gene="rhaT"
                     /locus_tag="ROH59_001072"
     CDS             19424..20458
                     /gene="rhaT"
                     /locus_tag="ROH59_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HDX4803590.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIV
                     SWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFY
                     AWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVA
                     ANIVGIGMAN"
     gene            complement(20455..21321)
                     /gene="rhaR"
                     /locus_tag="ROH59_001073"
     CDS             complement(20455..21321)
                     /gene="rhaR"
                     /locus_tag="ROH59_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HDX4803591.1"
                     /translation="MAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDF
                     CELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKL
                     NLDWQGAIPGFSASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVSFANEMAELLFGQ
                     LVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQ
                     FRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMT
                     PSQWRHLNSQKD"
     gene            complement(21377..22213)
                     /gene="rhaS"
                     /locus_tag="ROH59_001074"
     CDS             complement(21377..22213)
                     /gene="rhaS"
                     /locus_tag="ROH59_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HDX4803592.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQEQDGQYPSHWRVNHCVLQQVRQLVAQLEQQEEGNDLPSTASREILFMQLLLLLRKS
                     SLQESVENSASRLNLLLAWLEDHFADEVNWDAVAAQFSLSLRTLHRQLKQQTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            22501..23970
                     /gene="rhaB"
                     /locus_tag="ROH59_001075"
     CDS             22501..23970
                     /gene="rhaB"
                     /locus_tag="ROH59_001075"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDX4803593.1"
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWNVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQHGQRVGLPVAY
                     RDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTIYQLRALTEQQPELIPHIAHALLI
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINP
                     NDDRFINPDEMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
     gene            23967..25226
                     /gene="rhaA"
                     /locus_tag="ROH59_001076"
     CDS             23967..25226
                     /gene="rhaA"
                     /locus_tag="ROH59_001076"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDX4803594.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDRIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNP
                     AHHIDAVESKLFGIGAESYTVGSNEFYLGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLLDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLENVRTYEKKILSRRG"
     gene            25493..26317
                     /gene="rhaD"
                     /locus_tag="ROH59_001077"
     CDS             25493..26317
                     /gene="rhaD"
                     /locus_tag="ROH59_001077"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDX4803595.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAP
                     YHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
                     FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSG
                     PTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGQRFGVTPLASALAL"
     gene            26327..26641
                     /gene="rhaM"
                     /locus_tag="ROH59_001078"
     CDS             26327..26641
                     /gene="rhaM"
                     /locus_tag="ROH59_001078"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDX4803596.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFATIEIESEERWNAVASTDVCQRWWKYMTDVMPANADNSPVSSELQEVFY
                     LP"
     gene            complement(26682..28076)
                     /locus_tag="ROH59_001079"
     CDS             complement(26682..28076)
                     /locus_tag="ROH59_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HDX4803597.1"
                     /translation="MKKSTLSLAIGLLLACSTGMAKTQHLTLEQRMALLEERLEAAEM
                     RAAKAEGQVKQLQTQQAAEIREIKTAQGNTPVNGQSTTESEKKNATPPNLLLSGYGDL
                     KIYGDVEFNMDAESNHGLLAMTNADVNSDPTNEQWNLNGRILLGFDGMRKLDNGYFAG
                     FSAQPLGDMHGSVNIDDAVFFFGKENDWKVKVGRFEAYDMFPLNQDTFVEHSGNTAND
                     LYDDGSGYIYMMKEGRGRSNAGGNFLVSKQLDNWYFELNTLLEDGTSLYNDGNYHGRD
                     MEQQKNVAYLRPVIAWSPTEEFTVSAAMEANVVNNAYGYTDSKGNFVDQSDRTGYGMS
                     MTWNGLKTDPENGIVVNLNTAYLDANNEKDFTAGINALWKRFELGYIYAHNKIDEFSG
                     VVCDNDCWIDDEGTYNIHTIHASYQFANVMDMENFNIYLGTYYSILDSDGDKIHGDDS
                     DDRYGARVRFKYFF"
     gene            complement(28430..28990)
                     /locus_tag="ROH59_001080"
                     /pseudo
     CDS             complement(28430..28990)
                     /locus_tag="ROH59_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YiiG family protein"
     gene            complement(29072..29905)
                     /gene="fdhD"
                     /locus_tag="ROH59_001081"
     CDS             complement(29072..29905)
                     /gene="fdhD"
                     /locus_tag="ROH59_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDX4803598.1"
                     /translation="MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
     gene            30099..33149
                     /gene="fdnG"
                     /locus_tag="ROH59_001082"
     CDS             30099..33149
                     /gene="fdnG"
                     /locus_tag="ROH59_001082"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:30684..30686,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDX4803599.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSTWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSIGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGANPDQVLNMTWNY
                     AIPHEPKSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            33162..34064
                     /gene="fdoH"
                     /locus_tag="ROH59_001083"
     CDS             33162..34064
                     /gene="fdoH"
                     /locus_tag="ROH59_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase O subunit beta"
                     /protein_id="HDX4803600.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFNVPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            34061..34696
                     /gene="fdoI"
                     /locus_tag="ROH59_001084"
     CDS             34061..34696
                     /gene="fdoI"
                     /locus_tag="ROH59_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDX4803601.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            34693..35622
                     /gene="fdhE"
                     /locus_tag="ROH59_001085"
     CDS             34693..35622
                     /gene="fdhE"
                     /locus_tag="ROH59_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HDX4803602.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AEHNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTTRIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(35804..36046)
                     /locus_tag="ROH59_001086"
     CDS             complement(35804..36046)
                     /locus_tag="ROH59_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803603.1"
                     /translation="MNPLAGMDMSRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVD
                     QYLVNQSQTARTSVPGIWQGCEEDGVEYLRKLREKW"
     gene            36336..37184
                     /locus_tag="ROH59_001087"
     CDS             36336..37184
                     /locus_tag="ROH59_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803604.1"
                     /translation="MNKNESISYTEMQKFFAREIKEVGGRPITSKNLELSLLPIHARE
                     NLSAPEMPWYTEVNDIYMEFRRSPFWMVAGYVFLGFMLSLLSISILSIVAFSFYEMGF
                     NSDLLFLYLLAFVLGCFILPGAAKIAFFTPHYLPIRFNRKTQKIYVSDLIIEGNIFFG
                     KIKLTFHEYDWKDVEGWEVSRHFSKSMPYNGLHLVVNRENDINALRQTRVYTTRAPWS
                     AQEMARQKNYIPQIWLYCHNYMAYKTVSGAKNKPQPFIFLRNNWLFKWPKEMDKRSRS
                     SKILSE"
     gene            37500..37949
                     /locus_tag="ROH59_001088"
     CDS             37500..37949
                     /locus_tag="ROH59_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001523573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803605.1"
                     /translation="MKDNIHTAVIMAGEFLSANEWIRRKNQLKTSVHPASVASFAPYG
                     FNINQCDDDGNLWTNFPRPHIKLKIAPGKTACFLCRREELLFGYDEAHNHYQPNLNLV
                     LFVKNHGLHKDVYLKSHDDKSEYDSRILCNEKFTTYDFRKNRSRYSF"
     gene            complement(38134..38352)
                     /locus_tag="ROH59_001089"
     CDS             complement(38134..38352)
                     /locus_tag="ROH59_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDX4803606.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKSDRQRGEVVGVEEQGKWHEE"
     gene            complement(38749..39027)
                     /locus_tag="ROH59_001090"
     CDS             complement(38749..39027)
                     /locus_tag="ROH59_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803607.1"
                     /translation="MSTFNTRKDRDRNGKAKPHKHSGIPTLTGKWRHPSMDCWVNYST
                     PGDHEWKRLYTTLRRRADDRRQCHRVMQGDDPEGIVWFPDCYPQIYYY"
     gene            complement(39089..39301)
                     /locus_tag="ROH59_001091"
     CDS             complement(39089..39301)
                     /locus_tag="ROH59_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803608.1"
                     /translation="MTRNRAERRHHMVRLKKIRCRYRTAGDGSKKASGICFRTPCICS
                     CWMCGHRRYHNGPRVSEIRAKARYAN"
     gene            complement(39386..39676)
                     /locus_tag="ROH59_001092"
     CDS             complement(39386..39676)
                     /locus_tag="ROH59_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4803609.1"
                     /translation="MDKALFERLTHSMAQMNEIIEGTRQPSRTFEVDAMKIKEIRRAS
                     GLSQSKFADLISVSVDTLRNWEQGRRSPTGPAKALLRAIANDPQHVLQALNR"
     gene            complement(39677..39988)
                     /locus_tag="ROH59_001093"
     CDS             complement(39677..39988)
                     /locus_tag="ROH59_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDX4803610.1"
                     /translation="MLFIETEIFTEDVQKLLNDDEFSRFQFFLALNPDYGEVIPETGG
                     LRKVRWVSGGKGKRAGVRVIYFHQVKHYEIRLLLIYRKGIKDDLSPQEKAMLRLLNTR
                     W"
     gene            40217..41125
                     /locus_tag="ROH59_001094"
     CDS             40217..41125
                     /locus_tag="ROH59_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4803611.1"
                     /translation="MALEKGIAELVEEFIAAGRPSSRQQSITQRREGYIASAVLAGET
                     ETRVDIQTIELEGMTLRIVSPLNAPTLLPTIIYYYGGCFVSGGFATHDNQLRQLAYYG
                     QCRVIAVQYRLAPEHTFPAAHDDAQRGAELVRQHAERLGVDKQRITLAGDSAGGHLAL
                     VTALRLKRAGEWQPAQLILIYPMLDATAHFESYIRNGHDYIITRDTLLSGFEMYLPGI
                     ERRHPEASPIWRNDFNGLPPVHIITAEYDPLCDEGEALYHRMTGQGVQCTCQRYLGVI
                     HGFFQLGGISEAARSALRDVAWRAGR"
     gene            complement(41189..42130)
                     /gene="fabY"
                     /locus_tag="ROH59_001095"
                     /gene_synonym="yiiD"
     CDS             complement(41189..42130)
                     /gene="fabY"
                     /locus_tag="ROH59_001095"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HDX4803612.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(42175..42612)
                     /gene="dtd"
                     /locus_tag="ROH59_001096"
     CDS             complement(42175..42612)
                     /gene="dtd"
                     /locus_tag="ROH59_001096"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDX4803613.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQDMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            complement(42609..43481)
                     /locus_tag="ROH59_001097"
     CDS             complement(42609..43481)
                     /locus_tag="ROH59_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HDX4803614.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            complement(43475..44074)
                     /gene="yihX"
                     /locus_tag="ROH59_001098"
     CDS             complement(43475..44074)
                     /gene="yihX"
                     /locus_tag="ROH59_001098"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HDX4803615.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRVPLATLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLRAEGFSPDD
                     TVFFDDNADNIEGANRLGITSILVKDKTTIPDYFAKVLC"
     gene            complement(44215..45102)
                     /locus_tag="ROH59_001099"
     CDS             complement(44215..45102)
                     /locus_tag="ROH59_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001309103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HDX4803616.1"
                     /translation="MKTERKNEHYLALQQAFDAPWPGPVGELVTLEKGNIHLQIYPHD
                     GARITSLKAFGSEVLRQWQPQRRAFQYGCFPMVPWAGRLGNATLNAGGQCYSLPANKP
                     PHALHGMACYSTWEIIDKTADSLTLRMPLTSPWPWQGEVIQTFLLENDALVLQLEVHS
                     YADTFPASAGWHPWFAKKLTPQNTESLQVLFDADWQEEAGSDELPTGNRISPQVGPWD
                     DCFGFYDGVKVKLLWPGKLAMTMTSSANSLVVFDKQPDATCINPLTQAPNAINLTPEF
                     VTPDKPLVIETRWQFTPES"
     gene            complement(45092..46441)
                     /locus_tag="ROH59_001100"
     CDS             complement(45092..46441)
                     /locus_tag="ROH59_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HDX4803617.1"
                     /translation="MSEKLPAPREGLSGKAMRRVVMGSFAGALMEWYDFFIFGTAAGL
                     VFAPLFYPDSDPFIGLIASFATFGVGFLTRPLGGIVFGHFGDKIGRKITLIWTLAIVG
                     CSTFLIGFIPTYQEIGIWAPLILMVLRLIQGFGLGGEYGGAALMTIESAPESRRGFLG
                     SLPQTAASVGIMLATGIFALCNHFLTSEQFLSWGWRIPFWLSAVMLIVGLFIRLHTEE
                     TLDFQKQKTTNNKEKSVPPLIELFKKHPRNILLALGARLAESVSSNIINAFGIVYISS
                     QLALSRDIPLTGMLIASAIGIFSCPLVGWLSDRIGQKSLYLSGAGFCVLFAFPFFLLL
                     DSKSTLIIWCSMILGYNLGPTMMFAVQPTLFTRMFGTKVRYTGLSFAYQFSAILGGLS
                     PLIASSLLALGGGKPWYVALFLFAVSVLSFVCVWLIEPTDEQETASYRYIREQSHEN"
     gene            complement(46540..47973)
                     /locus_tag="ROH59_001101"
     CDS             complement(46540..47973)
                     /locus_tag="ROH59_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803618.1"
                     /translation="MSQITSPATYSISRPQDVIDIVNKNSAINTSIGVIFIALGGILI
                     DAYQAAMVGFGNKYIAAQFGISPGLAATVNASVLIAALIGGLLANRVINRFGQKRAFI
                     IGMGLCTIGAAAVAIAPSIWWVLVCRVIMGFGLGIDFPLATNAVAELRGSTSKKTGTS
                     VNLWQMAWYVSTTVVYLVLLPLLLSGIAEEQLWRYGIFIGAIFAVIFMILRYFFIGES
                     AMWAARVGRYQEACDILGKRYGVQARVAASGTTEAKFSEKAENKYSGGYGILFNDRYR
                     KRTILGCVVATMQAWQYNAVGVYLPLTLAGIISGGLTGALTGSAVVNALCGVTGGMIG
                     SFILQRLGTRRQSMYGFAVVTLALLSLGALATTNPWLSLGLLGSIIFFHSAGPGGLGM
                     TIATLSYPPAIRPTGVGFARAIMRTGAIAGLIFWPMLWGALKTEAFYWLAIVPFLGFL
                     TCVLINWEPLGANVDAEDAEVLAELKK"
     gene            complement(48043..49053)
                     /locus_tag="ROH59_001102"
     CDS             complement(48043..49053)
                     /locus_tag="ROH59_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001494590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDX4803619.1"
                     /translation="MDKITQVLFSDIGKVTTQYVEVPHQQLKPHEVRIAPVFYGICGS
                     DLHVLKGGHPFAKPPVVPGHEIAARVTEVGSDVKNVQPGDHVVVDPIMACMECRACKA
                     GRFNLCEPPQVAGFRAPGFARSQHIVPARNCHVAPASLPLKVLAFAEPAACARHCVNR
                     MPKASLESVLVIGAGTIGLSIVQALRIMGAGKITVIEPDAAKRALALKLGAAEVWAPG
                     ELAADVRFTGAIDVVAAQATLNDACTRVYAGGTVVCMGVPSGPREIPLPMMQRFERDL
                     LNSGMYIPEDFDAVIEWLADGRFDTSELVTDLFAIEDAAAAFERAQQNDSIKVMLQFA
                     PE"
     gene            complement(49086..49973)
                     /locus_tag="ROH59_001103"
     CDS             complement(49086..49973)
                     /locus_tag="ROH59_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDX4803620.1"
                     /translation="MSSHFTPFTLKDISRPGGGFAMLAVDQREAMRLMFAAAGQPKPI
                     ADSVLTDFKVAATRILSPYASAVLADKQFCLEQIVEQGAVANSCGLIVAADLFIPGNG
                     IPVDSVEIDMSVDPHKAREMGAKAMKLLVLWREDEPAEERLAMVDKFVRRCRSAGLVS
                     IIEPVVRPPRRGWDFDRESAIVAAAAELGGTEADLYKAEMPLGGKGDEKTLLAACQQL
                     NDQMKMPWVILSSGVDADIFGRAVSIAMKGGASGFLAGRAVWASVVGAQDPQTMLRDV
                     SVPRLQRLAEIVDEGIAQR"
     gene            complement(49998..50876)
                     /gene="yihU"
                     /locus_tag="ROH59_001104"
     CDS             complement(49998..50876)
                     /gene="yihU"
                     /locus_tag="ROH59_001104"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001318159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HDX4803621.1"
                     /translation="MATIAFLGLGQMGSPMANNLLQKGHSLQVFDVNTQAVDALVTQG
                     ATAAQTPAEAAASAEFIITMLPNGDIVRQVLLGEKGVCETVSSDALVIDMSTIHPLQT
                     DALIRELQEKGINMMDAPVGRTSVNAIDGTLLILAGGTDEQIARARPILMCMGNELVE
                     AGGPGMGIRVKLINNYMSIALNALSSEAAVLCESLGLNLDVAIKVMSGTAAGKGHFTT
                     TWPGKVLKGDLSPAFMVDLALKDLRIAVDVARKTGAPLNMGIAAESYYAAASQDGKGR
                     QDWSALLNQVRQQAGL"
     gene            51049..51945
                     /locus_tag="ROH59_001105"
     CDS             51049..51945
                     /locus_tag="ROH59_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX4803622.1"
                     /translation="MTRIACVGITVQDRIYSLPTLPEGGGKYQANHYLEIGGGPAATA
                     AVAIAKLGVEVDFIGRVGDDSCGNTLLAELEGWGVNTAFCRRYPNARSSQSAILVDQH
                     GERIIVNYPSPDLGTDAEWLEAIDFSRYDLILADVRWHSGTEKAFSLARLAGVTTLLD
                     ADMTPQDISPLVALADHAVFSTPGLKRMTGLQSPEEGLFQATTQTAGKVYVTLGSEGS
                     LWIEDGHLCQQEAFSVNVVDTTGAGDVFHGALAVALAEKMPTKEAIRFASAVAAMKCT
                     QPGGRAGIPNREQTESFLSLYA"
     gene            51985..52773
                     /locus_tag="ROH59_001106"
     CDS             51985..52773
                     /locus_tag="ROH59_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4803623.1"
                     /translation="MSIIEVTGNPRHDQLVHLIAERGYMNIEELAQLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRVSSVMNTAFEQRELSLTAEKRAIAEAVADYLPERCTVFI
                     TIGTTVEAVARALLNRRDLRIITNSLRVAQILYKNQDIEVMVPGGTLRAHNGGIIGPG
                     AVDFIEGFRADYLITSIGAIEHDGTLLEFDVNEALVARTMIKHARNTLLVADHTKFTA
                     SAAVSIGNARNVRAFFTDAPPPNSFCQLLSEENVELVVAEQEVS"
     gene            complement(52881..54704)
                     /gene="typA"
                     /locus_tag="ROH59_001107"
     CDS             complement(52881..54704)
                     /gene="typA"
                     /locus_tag="ROH59_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HDX4803624.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            55077..56486
                     /gene="glnA"
                     /locus_tag="ROH59_001108"
     CDS             55077..56486
                     /gene="glnA"
                     /locus_tag="ROH59_001108"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HDX4803625.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            56660..57709
                     /gene="glnL"
                     /locus_tag="ROH59_001109"
     CDS             56660..57709
                     /gene="glnL"
                     /locus_tag="ROH59_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HDX4803626.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRITESIHKVAERVVTLVSMELPNNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            57721..59130
                     /gene="glnG"
                     /locus_tag="ROH59_001110"
     CDS             57721..59130
                     /gene="glnG"
                     /locus_tag="ROH59_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HDX4803627.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESNVPE
                     STSHMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            59242..59352
                     /locus_tag="ROH59_001111"
     CDS             59242..59352
                     /locus_tag="ROH59_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HDX4803628.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(59585..60958)
                     /gene="hemN"
                     /locus_tag="ROH59_001112"
     CDS             complement(59585..60958)
                     /gene="hemN"
                     /locus_tag="ROH59_001112"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDX4803629.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEQQW
                     DLLFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(61147..61656)
                     /gene="yihI"
                     /locus_tag="ROH59_001113"
     CDS             complement(61147..61656)
                     /gene="yihI"
                     /locus_tag="ROH59_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HDX4803630.1"
                     /translation="MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGS
                     RAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELL
                     ETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQE
                     DMMRLLRGN"
     gene            62238..62870
                     /locus_tag="ROH59_001114"
     CDS             62238..62870
                     /locus_tag="ROH59_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDX4803631.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            complement(63252..66038)
                     /gene="polA"
                     /locus_tag="ROH59_001115"
     CDS             complement(63252..66038)
                     /gene="polA"
                     /locus_tag="ROH59_001115"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDX4803632.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQPPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAARPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
     gene            66396..67328
                     /locus_tag="ROH59_001116"
     CDS             66396..67328
                     /locus_tag="ROH59_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HDX4803633.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVRGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWALDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQDK"
     gene            complement(67369..68799)
                     /locus_tag="ROH59_001117"
                     /pseudo
     CDS             complement(67369..68799)
                     /locus_tag="ROH59_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418298.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
     gene            complement(68953..69579)
                     /gene="dsbA"
                     /locus_tag="ROH59_001118"
     CDS             complement(68953..69579)
                     /gene="dsbA"
                     /locus_tag="ROH59_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HDX4803634.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKELTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK"
     gene            complement(69596..70582)
                     /gene="srkA"
                     /locus_tag="ROH59_001119"
     CDS             complement(69596..70582)
                     /gene="srkA"
                     /locus_tag="ROH59_001119"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HDX4803635.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            complement(70659..70928)
                     /locus_tag="ROH59_001120"
     CDS             complement(70659..70928)
                     /locus_tag="ROH59_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HDX4803636.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            70998..71582
                     /gene="mobA"
                     /locus_tag="ROH59_001121"
     CDS             70998..71582
                     /gene="mobA"
                     /locus_tag="ROH59_001121"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HDX4803637.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQVSGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPHDLAARLTHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMAF
                     MRLAGGHAVDFSDRKEAFINVNTPEELARWQEKR"
     gene            71564..72091
                     /gene="mobB"
                     /locus_tag="ROH59_001122"
     CDS             71564..72091
                     /gene="mobB"
                     /locus_tag="ROH59_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDX4803638.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLHFLASRMDTSKL
                     DLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQDG"
     gene            complement(72196..>72300)
                     /gene="rrf"
                     /locus_tag="ROH59_001123"
     rRNA            complement(72196..>72300)
                     /gene="rrf"
                     /locus_tag="ROH59_001123"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        18364 a        18441 c        17477 g        18018 t
ORIGIN      
        1 atttgccttt cagcgccgaa tcatcgtcaa tcttttcggc cttcagttcg gccacatcgc
       61 cataacgctt aaaaataccg tcaggcagga tgccgcgcag atgttccagg ttaatgcggc
      121 aaccatagac tcgcgggtca aaggtttcag ccatttcctg aatatcctgc gcactgatga
      181 cacgcccgtc acaggtgtca ccctcaacgc cgatacgaaa gaattttgag actttttttg
      241 ccattgtcag gagtcctgaa tagtgattag aggagtcaca tgtcggcatc agtttcccga
      301 cgatgcgcat cctccgccat cagtcccgga tggcttatca ctgacacaac agcaccttag
      361 cgaatcgcgg ggcgcgactc agtagccttg ccgtgtattc atcacggcga ggtattcatg
      421 accatcacca cagacaccac tcttttacac gacccgcgtc gtcaggcggc gctgctgtac
      481 tggcagggat tttccgtgcc gcagattgcc gccatgttgc agattaaacg cccgacggtg
      541 cagagctgga aacagcgcga cggctgggac agcgttgccc ccatcagccg tgtcgaaatg
      601 agtctggaag cgaggctgac ccagctcatc atcaaaccgc agaaaaccgg cggtgacttc
      661 aaggaaattg acctgctcgg acgccagatt gaacgactgg cacgggtcaa ccgttacagt
      721 cagaccggca acgaggctga ccttaatccg aacgtcgcta accgcaacaa aggcgggcgt
      781 cgcaaaccga aaaagaattt tttcagtgac gaggccatcg aaaagctgga gcagattttc
      841 tttgagcagt ctttcgaata tcagttgcac tggtatcgcg ccgggcttga gcaccgcatc
      901 cgcgatatcc tgaaatcccg ccagattggc gcgacgtttt atttttcccg cgaggcgctg
      961 ctgcgcgccc tgaaaaccgg tcataaccag atttttctgt cggccagtaa aacgcaggcg
     1021 tatgtgttcc gcgaatacat catcgccttt gcccgtctgg ttgacgttga cctgaccggt
     1081 gacccgattg tcctgggcaa taacggcgca aaactgattt ttctcggcac caactccaac
     1141 accgcgcaga gccataacgg cgacctgtac gtcgacgaga ttttctggat cccgaatttt
     1201 caggtactgc gtaaggtggc atcaggtatg gcctcacaga gtcacctgcg ctcgacctat
     1261 ttctccaccc cgtccacgct ggcgcacgac gcctacccgt tctggtcggg tgaactgttt
     1321 aaccggggac gcgccagcgc cgccgaacgc gtggaaatcg acgtcagtca taacgccctt
     1381 gccggtgggc ttctctgtgc ggacggtcag tggcgacaga ttgtcaccat tgaggacgcc
     1441 ctgaaaggcg gctgcacgct gttcgacatt gagcagctca aacgcgaaaa cagcgccgac
     1501 gattttaaaa acctgttcat gtgtgaattt gttgacgaca aggcatcggt gttcccgttc
     1561 gaggagctgc aacgctgcat ggtcgacacg ctggaagaat gggaagacta tgcgccgttt
     1621 gccgccaatc cgttcggctc ccgcccggta tggattggtt acgacccgtc acaccgtggc
     1681 gacagcgccg gatgcgtggt actggcaccg ccggtggtgg ccggtggcaa attcagaata
     1741 cttgagcgtc accagtggaa aggcatggac tttgccaccc aggcggaatc catccgcaaa
     1801 ctcaccgaaa aatacaacgt cgaatacatc ggtattgatg ccaccggcct cggtgtcggc
     1861 gtgttccagc tcgtgcgctc gttctatccc gccgcgcgtg atatccgcta cacgccggaa
     1921 atgaaaaccg caatggtgct caaggcaaaa gacgttatcc gccgtggctg tctggaatac
     1981 gacgtcagcg ccaccgacat caccagctcg tttatggcta tccgcaagac catgaccagc
     2041 agcggacgca gcgccaccta tgaggccagc cgcagcgagg aagccagcca cgccgacctc
     2101 gcctgggcga ccatgcacgc cctgttaaat gagccactca ccgccggtat cagcaccccg
     2161 ctgacatcca ccattctgga gttttactga tgagcaagaa aaaagggaaa acaccgcaac
     2221 ctgcggcaaa aacaatgacc gccagcggcc cgaaaatgga ggcattcacc tttggtgagc
     2281 cggtgccggt actcgaccgc cgtgacattc tggattacgt cgagtgcatc agtaacggca
     2341 gatggtatga gccaccgatc agctttaccg gtctggcaaa aagcctgcgg gctgccgtgc
     2401 atcacagctc accgatttac gtcaaacgca atattctggc ctcgacattt atcccgcatc
     2461 cgtggctttc ccagcaggat ttcagccgct ttgtactgga ttttctggtg ttcggtaatg
     2521 cgtttctgga aaagcgttac agcaccaccg gtaaggtcat cagactggaa acctcaccgg
     2581 caaaatatac ccgccgtggc gtggaagagg atgtttactg gtgggtgccg tccttcaacg
     2641 agccgacagc cttcgcgccc ggctccgtgt ttcacctgct ggagccggat attaatcagg
     2701 agctgtacgg cctgccggaa tatctcagcg cccttaactc tgcctggctg aatgagtcgg
     2761 ccacgttgtt ccgccgcaag tattacgaaa atggcgcaca tgccggatac atcatgtacg
     2821 tcaccgatgc cgtgcaggat cgcaacgata tcgaaatgct tcgcgaaaac atggtcaagt
     2881 cgaaaggccg caacaacttt aaaaacctgt ttctctatgc cccacagggg aaagccgacg
     2941 gcattaaaat tatccccctc agtgaagtgg cgacgaagga cgattttttt aatatcaaaa
     3001 aagccagcgc cgctgacctg ctggacgcgc accgcatccc ctttcagttg atgggcggca
     3061 agccggagaa cgtcgggtcg ctgggtgata ttgagaaagt ggcaaaggtc tttgtccgca
     3121 atgagcttat cccgttacag gacaggattc gggaaataaa cggctggctc ggtcaggagg
     3181 tcatccgctt taaaaactac tcactggaca ctgacaacgg ctgaacatcg ccgcctgcgg
     3241 gcggcttttt tacaccccgt catcacaccc tcacacgctc accaccgcac aaaacacccc
     3301 gcagacacac caacgccccg gcgcacactc taaacgccat cacgacgcgc tcagacgctg
     3361 aaaaaataaa atcagcacca ccgccagcgc gcagtgcttt ccccgcctcg cccgcccgct
     3421 tcatgggtcg gttttgatgc aattccaaaa gccgtccaaa ctctcttagg ctaaatgtcc
     3481 aacgagaaaa tagttctttg aatgtgaatg cattttaatg cagagttatg cccagcattt
     3541 ttgtacactt cgatgtatca aatgcgctgc aaacgatcaa atatggatgt tttatcaagc
     3601 atcccccaaa agatatttac atcatcccat gaggttaaga tggataacaa aatcgtagaa
     3661 attgagacaa ataagcttga ttttgaccct aaaaacccac gtttctttcg tctcaatgat
     3721 gccagtaacg ctgcaacagt cattgaggaa atgttagatg acgaaagtgt ccacgatcta
     3781 atgctatcaa tcggtcagca aggttacttt cctggagaac ctttattggc agtaaaaagc
     3841 aatggaaact acatcgtggt tgagggaaac agacgcttag ctgctgtaaa gttgctcaat
     3901 ggagatctgc ttcctccaaa aagaaaactt aaaggtgtgc aagaaatcat tgatgatact
     3961 accaataaac ctaagaagct tccctgcatc atttatgaaa accgagagga tgtactgaga
     4021 tatatcggtt atcgtcatat aactggggtc aaagaatggg actcattatc taaagccaaa
     4081 taccttaaag agttatgtga tactttttat tcacatgagc ctaaagagat agtattaaaa
     4141 aatctggctc gtgagattgg gagtaaacca cattatgttg caacacttct cactgcactg
     4201 aacttatatg aagtcgcgca tgaccatgag ttttttaatt tacccatgaa ggcttctgac
     4261 gtggaatttt catatataac cacagctttg ggatattcaa aaatcacaaa ctggttaggt
     4321 ctacaggata aaaaggattt tttagaccca aatttaaatg aagaaaacct taagcgttta
     4381 ttctcttggt tttttgtgcc tgaccaacaa ggtagaacca tcatcggtga gtctcgaaga
     4441 ataaaagata ttgcagcagt ggttgagaaa cccgaagcaa ttgaaattct catgaaaagt
     4501 tcaaacttgg atgaagcata tctatatacc agcggagaaa gagaagcatt agataaagca
     4561 ctaaacgcag ctagtgttaa attaagagta gtttgggata tgctacttaa agctaaagaa
     4621 ttaacattag agcatgaaga ggctgcatct gaaatttttg agatgtcaaa aaatattaga
     4681 aatcagatca gaagcaaaag ggaggatgat tgagattatg attacaaatc ttgattcaat
     4741 gccttctaat gagccttatt tatgggctga ttatattgag atattggcct taactaatat
     4801 cgacaggtca ttcagtcgag gagacctata tagcacactg caagctcaac ccgaagcagt
     4861 actagctgaa acagatgaag cagaagaaga gggcgtttat gatgttgatg atgaaaatga
     4921 tacgcctgta cgcaagagaa caaaacgaag tgttagtcga gcatatactg acagaaagtg
     4981 gagctatgcg ataggcttca tacgacaacg cattgattta tttggggata gttacccttt
     5041 tactttatca gaagacaacg atactgtaga gttacgtgat atatcagaaa agccactgga
     5101 acatttagaa agactatatt tagctttact aatctgtgct aacataaaat atgtcaacat
     5161 aatgagcaga agagagataa cgcgcagttt tgaactaatt agtttaccta tttttgaaag
     5221 cctaatgcct agcggtagca taataaaagc atgctgggct tctggtggtc aagcggcccc
     5281 ttacactgga actctatata ataaatttaa gagtattgct tccgatatcc gttgcacagc
     5341 gaacttcaaa gaacgagatt tcagtcgagg aaatagtggt gacggaggcc ttgacataat
     5401 tgcctggcat ccaatgggag atcaacgaga tgccatccct atttcttttg ttcagtgtgg
     5461 ctgttctcaa gaagagtggg aagcgaagca gcttgaggcc tcacctgcga tgctctacag
     5521 taaattcccc gtagctcacc gatgggcaac ttattatttc ttacctcaag atctacgatg
     5581 gatagatggt gagtgggcgc ataaaaataa gttaggcgat gctatttttg ttgatcgcct
     5641 aagattaatc aatttaacca gagcatctga taatattgat cacagtcaaa atattagcta
     5701 tctagatatc atccttgatc cttccagcgc gatcgctgct taatcccata aatctggaag
     5761 gtttctagca accgcctcaa acaatggagg cggtactgca ttacctacca cagtatattt
     5821 catattaata gaagcccgtt cagtttctgg gaaaattaaa tccccaaaac cttgtaaaat
     5881 agcagcctct cgatagctaa acctacgagc tggtgcatcc gaagtaaatt gccacttatc
     5941 aggtcccaat ttttctaatg ttggacttat tggatgtaga ggcatatgtc taggatttgc
     6001 aacaattgtt ttagatatct gatcccaatc ttgcctacgg tttcgcgata gataatacca
     6061 atgaaaatcg gcgtcataaa actcgccaac aggccaaaca ggcatatgcc caatagcatc
     6121 acgaattgtg gaatatggtg tcaaaccatc accatgtgtt ggttttggaa atttgtatgt
     6181 aataccgtag tcctttcgta ttcctacgat aaagattcgc ttcctatctt gggatacccc
     6241 ataatgggac gcattcagaa tttgcgagct tactgtataa cctgcttctt cgaaaacttt
     6301 gaattgatcc tttaataaat gctcaaagtt acgccttacc ataccagaga cattctctac
     6361 aatgaatgct tttggcttaa ttttactcaa agcacgggca aactctaaat atagtgtatt
     6421 aatctttcta tctgccttcc ttgccccacc ttgactaaat ccttggcaag gatagcatcc
     6481 gatgagcaac tcagcagaag ggaacgactg gagccctgag atatcgccca aaatgtagtc
     6541 agtttcagga tggttttcta agtaaacgtc ccttgcgtaa ggcaaaatat catttgccat
     6601 aagcacattg aaacctgcgt tcaaaactcc cgcatcagaa ccaccacatc cagaaaaaag
     6661 tgaaactaca gttggcattg acccctccta aaaaccgacc gcgtattata gcgaaacacc
     6721 ccgttgggaa aagctagatt ttgccaagtc ttgatattct cacgttttag tagttgtggc
     6781 catctttaac gagaaaaaga taaaattgac ttctcattaa ttttcaatag gtttaattgt
     6841 aagctcaaac taacgcctcg cgacactcgt tattcaaccc cgccagccct gaaaacaagt
     6901 ttcacgactg gcggcgttct ctatcgtctg cgttgtggtg gcgcaactct ggactgaccg
     6961 atatggttaa accgcccgta attatcccgg actatttcgg cacacccgac cagctcatcg
     7021 ggcgtcagat tttcgttgac cataatccgc tgtaaacgct gaacaatagc catcagcttg
     7081 atatttttag ttttatggtg cggtatctcg cctggtattc tgtgcattat ccaagccacc
     7141 cgttttgctg tgcacgctcc atctgttcat ctgaatagtt ccatgctcca tccgtggcaa
     7201 ccattgcccc gccagacatc cccgtctctg gttcatacat aacagcaagg ccgagctgat
     7261 gcataatttc atgattaatt ctgaatacca ggccacgctc actaagttct ttccagttca
     7321 caatctcata tgcgcctgta ttaagcagct caatacttag caagacataa tcttccagcc
     7381 agtctgacag gtcagtaaca tctgttatcc gggcttcaac atttcgcccc gtatacacac
     7441 cctgcaccca ttcatacaaa atcaacgtgt ccccgcgctc ataattacgg tcatttttcc
     7501 ggaactctgc acgtttcttt ccttccagca caaggtcgaa atattttgcg tgcagcttta
     7561 cctcgtgaat ttttgccatt atgtccactc cattactgtt gagaatcccg gccactcatc
     7621 agcgaccgga tacgtgaatt ttttcccgtc ataatttacg gtcgcgccac gcgccagcgc
     7681 ctcaagctcc catcgctgcg gcctgatacc gttctgagca aggtcaacgc ggatacgggt
     7741 aatttgcgtt cgttccgacc gggtcagtct ggccgatggc gctatttcat gtggttttaa
     7801 cgggcttccg tttctctgct gacgatttgg tgttctcagt tcgtgtttta atgcacctct
     7861 gagcgccctc acgacctctg gctcattcca ttcgataaca ccgtcatcaa ccagattaag
     7921 cacggctgcg gcatgttcat aaggtgtggg agccggtaac gaagtatcac tgccggtgag
     7981 ctttccacag ttattgacag gactccgagg cgcggcgatg ccgcttttta aagtcaaagg
     8041 ctcaacgacc ggaactttcg gcacaatgcg ccagtccgtc gttctggtga tatgaatatg
     8101 acgcgcgccg agatgcggcg cgtaaatacc gaccactctc tcgacttctt cctcgtactc
     8161 gttaacgtca ctcgacgggc tacgggcaac cctgacagtc tgacaatcgc gcgggacatt
     8221 tgccccaccc tgcgcgctga tatacaacgc aaaatcacca ctgtctgcgg cagcgcgagc
     8281 agcctcgacg cgttcgtcaa actcatcagc aatactgacg ccgcgaggta atttgcgtag
     8341 ttcacggtaa gcccccattg tcggtaggcc aaccgtttta aattgcggaa tgcgccacgt
     8401 tgacgcccat gcggtaacag ccgcggcagt gtctttcagc ggcctgccgg tatcgttatc
     8461 gagctgacca tccagtgcat agccgtcgat gttttttgaa atgtatttcg cgatataccc
     8521 cgcagcaccg ccccgattaa ggtgttttgc ctgaaaacgg tttcgcgcgg ctcctctttc
     8581 gtcgccatcc tctttgagcg catagcgacg catgatttcg ataatctggt tacgctggcg
     8641 cgaattacaa aaaagcatca tatgccagtg cggcgttccg tcgtggtgtg gctcgacgac
     8701 acgcaaaccg tagacctgta aatcattatc cttgaatgcc gtgcgcatca ggctccagat
     8761 acggcagaga taacgctgcg catcctttgg attaaatgcc tcatcgttcc agccgtgatt
     8821 aagctgcacg gttttacttt cgccttttcc tacctgacgt gtcgggtgat actttgacgg
     8881 cgcggtcagc gtgataaaca tccccacatc accctctgca gcggcgtaac gctcaatacc
     8941 ggcaatggtg ttcatcagct ccatccggcg aatttcagga ttagaaatac tgcccatcac
     9001 cttactgata aggtcgatgc gctcgccggt ttccctgttt tcaaggtcac acgatttaag
     9061 aaattccaga tttgcctggc ggcgcgcacg cacatcacga atggcatgtt tactggcata
     9121 aggtgaacgg tctttattga cctccccgac agcaatcagt aacgcctcat gccagcgcat
     9181 acgctggcct ttaagctgac taatccacca ctcatcgtta aacaggcggg caatggcaga
     9241 atatgcctgc ctcgtggtca tctgcccttt acggtatttt ctccagtaca gcggggaaat
     9301 attgaaagca cgtgcagcgc cagcaacatg accatacagg tgagcctgcg cctcatccgt
     9361 aaacagcgat tctttttcgc catgggcatc cacccaggca tcgcagagtt cctcatacat
     9421 catgaaaagc tgcgatgaga tacgggcggc aaactttttc agctccttgt cattcattcc
     9481 cggcaggcgc gcatagtggt cacgctctgc cagaaacagc aacgacgcgt cggtgttcat
     9541 ttcatggcgc tgattcacac gctcaatgcg cggccataaa cgacgctgaa aagtggatgt
     9601 gaggaaataa aacccgtgca ccgggctttt attgcgccgg atgtagtcat agcgtgaagt
     9661 aaacagcgag cgcaaaaagt aaggcaggcg gttaatcgtg gataaaacac cttgcacctg
     9721 acgcatctca tcacgtgtaa ggggtctttc gcgcccgacg gcctcgcgtg gcgcgttcca
     9781 tgcataagca ccggtaaaca tcttaccggt gcctgcggca aatgctgacg gagggacaaa
     9841 acgcccggag gctttaacgg ccatatgagc caaaagcctc tgaacaacgc ctgctgagtt
     9901 gctcaacctg cgcgtttaaa tcagcaaaag actttgcgct tccggtcaga atatcgtgat
     9961 gcatcaggcc ggaaacgagc tggcttaatt tcgggtaata accaaccacc gccagccatt
    10021 cctgaccggc gtttttaccg ctttcagctc tctttttctc gtggagaata aactgaaagc
    10081 tgtcactggt aacgacataa cgttcgccaa tttcaatacg aatactcatg ccgttctccg
    10141 gtaatgtttg ttttttgctt caaagactga ctgacaggaa acacaacgcg tggctgacgg
    10201 ataagccgca cgacgggcag caggtattgg cgcgtcacac tcttcgcaaa ccagcgcaga
    10261 agcaccgcaa tgttttaccc ttgccgcgtt aatctggcgc tccagtaatt cagcctgttg
    10321 ttcctgaata aaatctacgt tgtccggcat taccagttcc ttttgtcgtt aaggttttta
    10381 aattcatcag cgcaatagct ggcgatttct gtcgttaatt tcgtcagttc atccacggag
    10441 gagatttgct tgtgaaacac agcgcgttta acaagtaaat tgaccacatc agacaggagg
    10501 tttaattcgt tctgataaat cgcgataaca gactcagtta tttcgcgttt ttctttatca
    10561 agaccaagtt gaataagaga caaatcgcca tttttcataa cggcgatttt tagggcgtta
    10621 ttcagtaata caactgaacg agaacaggac atcaaagcac ctccccgcga gacaatccga
    10681 tattgtgaaa tttttccgac tcctgactga gcagctcgac tatctccacg cgggataact
    10741 ccgcctttgt gatgtggcga atcatggcgt caagatgaga agaaaagcgc gtcgctgcgt
    10801 cggcctgtgc ttcggttctg gcctgttgca gcagtaatgc gtatttaccg cactgatttt
    10861 cagaaactgt atgcatgact ttctccaggc aaaaagaagc cccgcacgat taagtgcgtt
    10921 aaaaactctg gttaattact taatgcagat attgctctgg ttttaccgac gtcagaattg
    10981 tcggtgcata ctcaaacagg ctgaataatt cacgtaatgc acggaataaa gcatcacgcc
    11041 agtaacatga ttcttcatta attcgccagt atggctggtt gaattctttt tcagtcagtc
    11101 gtgcgtgcat aaataaagtg cgacgctgac tgactgttaa aaaactaata tatgcatact
    11161 cacttgcgcc aacctgacgg cgttttgaga atgcgccacg caattcatca attgcacaaa
    11221 ccagtcgttc acgttcgacg tcgttcattt cttcaaaacg catcgttgcg tgacgctgtt
    11281 ttaactgtgc atgaaagcaa accgttagcc gttcgcgctc catcatctga ttataataat
    11341 cacatgtatc ctgccagcga gggacggcaa gatgcttgcc aattatccgg cgcatagctg
    11401 ctggctgttt ttcaacgaga ttaagcgtca tcactgtcat ttccagcccc tccggctttt
    11461 cagaaaggtc agagcctttt ttaacggact ctgttttttg gtgcggataa tgattccctt
    11521 acgcccctta ccgtgggtga tggtgaagtc aatcgccctg gggctttcgt tacgcagtaa
    11581 ctgagcaata caacgcggtt cactcataat cacaacccca tccacaaaag ccatgcatca
    11641 cgctgttcaa ctggtcggtt ataaaacgcc tctcgtacag cgcgattaaa ctctggaatg
    11701 aaaacccact tctcaccgac acgagcgttc ggcttacttg gatcacgaag ctcaataact
    11761 ggcaacttat tctcttttac catcttgact acagccgttt ctggcttacc aagtaactct
    11821 gcaaacttaa ccgtatgtac cgcatcaatc gggtactgaa tcacatagtc attgacttcc
    11881 attgattagc cctttttgct ttcgtgttac ccttattaga tccagtccct tctaggtcgc
    11941 acctgtcctt tctagggact ggctaacaca ctcaaaaggt caccaataca caaccttttg
    12001 acgggaatat aagtcaccaa taggttactg tcaaatgcag acattcgaaa aactgaaagc
    12061 gattaggaaa gcagaaggct taacacaggc gaaattcagc gaaattagcg ggatagctct
    12121 aggaacagtc aaaaattacg aaagtgggca taaagaccct ggtctcagca tcgttatgcg
    12181 agtcacaaat acgcctttat ttaaaaaata tacgctctgg ttaatgactg gtgatacgtc
    12241 accacaagct ggtcagatcg cgccggctct cgcacacatt gggcaaaaac caacagaatc
    12301 agaccactcc gaaaaacaga ctgggtaaca ctctataaac attacatttt caccatttgt
    12361 taccaagatg gtgaatacag cgtcagaggg ctttcttatg tcaattaaga agctcgatga
    12421 tggacgctat gaagtggaca ttagacctcg cggtcgcgac ggaaaacgca tccgcaggaa
    12481 atttgaaaga aaagctgagg ctgtagcatt tgagcgatac acaatcgcct acgccagcca
    12541 gaaagaatgg gcaggtcagc gagcagatcg cagaactttg agtgagttgc tgaacatctg
    12601 gtggaaatat cacgggcaaa accacgagca tggaacaaaa gagtttaatc atctgctcaa
    12661 aaccatcagc ggcataggtg atataccagt gagccggatg agcaaaagag ctttgatgga
    12721 ttatcgttcc atgcgactac gtgatggtat cagtgccgca acgataaacc gtgacatgta
    12781 ccgattatcc ggcatgttca caaaattaat tcaattggat gaattttccg ggcaacaccc
    12841 aattcacgga ctgccgccac tggcggaggc caaccctgaa atgacgttcc tggaaaaagc
    12901 agaaatcgaa aaactgttaa atgttttgga tggtgatgac ttacttgtcg cacttttatg
    12961 tctgagcact ggaggaagat ggacggaagt tgccacgcta aaaccagcac agattacaaa
    13021 ttgcagggtt accttcctga aaaccaaaaa cggtaaaaag cgaaccgtgc cgatttctga
    13081 ggaactggag aaaaaagtta aagaggaggc cagcgctaaa ttattcaaag ttgattatga
    13141 gaagttttgc gggattttac gcagagtgaa gccagatata ccacccaatc aggcaaccca
    13201 catcctgcgg catacattcg caagccattt catgatgaat gggggcaata taatcgcact
    13261 gcaacagatt ctgggacatg cgagcattca gcagacgatg gcctatgcgc accttgcgcc
    13321 tgactacctg caaaatgccg tcgcgctgaa tcctctaaaa ggcggagtga cgttataaat
    13381 ttcccttctg agtgtccaca tagtgtccac actctcagaa ctttgtagcc cttccagtcc
    13441 cttataggtt ttcttaagtt actgttttct tacgaaaacc gatgtaagtg attgataaaa
    13501 aaaaccccca catcatgtgg gggaagacag ggatggtgtc tatggcaagg aaaacagggt
    13561 ttactactgg gaacgtgagt tgctactact caatagcttc aacgatgaac ttttttgcca
    13621 ttgcgtcacg tcgcgcaact gctccattcg ttgttgatgt ttctcgttta aaaccgcttg
    13681 ctgctccggc gttaacaggc gatacatttg gttgcggact tttgccatct caacctgacg
    13741 agcaatttgc tcattcgcca ttttttctgc ctgtgcgcgc acagcgtttt catcaaaatt
    13801 ttctgcggtg acaaggcgat gcattgtctc cagttcgcta acattaacag gaggctgttc
    13861 gtgccgggcc tgttgcataa gatctcgcat ctgctgacgc tgatgttcgg ttaaacttat
    13921 gccgtcgaac atatggctct gcgtactgcg ctgcgtaagt tcttcacccg gatgccagtt
    13981 atcgcctgaa ccgacttcag cagcgtggct taatgaactg actgccagcg ttgaggccat
    14041 gacggcagcg gtaactatgc gcatcatttg ctcccaaaat ctttctgtcg cgattcaacg
    14101 atagagagtt tacgattcag gctgcaaaca tgcgtcaggg ggtgtaaaac aacgtaaagt
    14161 catggattag cgacgtctga tgacgtaatt tctgcctcgg aggtatttaa acaatgaata
    14221 aaatcctgtt agttgatgat gaccgagagc tgacttccct attaaaggag ctgctcgaga
    14281 tggaaggctt caacgtgatt gttgcccacg atggggaaca ggcgcttgat cttctggacg
    14341 acagcattga tttacttttg cttgatgtaa tgatgccgaa gaaaaatggt atcgacacat
    14401 taaaagcact tcgccagaca caccagacgc ctgtcattat gttgacggcg cgcggcagtg
    14461 aacttgatcg cgttctcggc cttgagctgg gcgcagatga ctatctcccg aaaccgttta
    14521 atgatcgtga gctggtggca cgtattcgcg cgatcctgcg ccgttcgcac tggagcgaac
    14581 aacagcaaaa caacgacaac ggttcaccga cactggaagt tgatgcctta agtctcaatc
    14641 ctggtcgcca ggaagccacc ttcgacgggc aaacgctgga gttaaccggt acggagttta
    14701 ccctgctcta tttgctggca cagcatctgg gtcaggtggt ttcccgtgag catttaagcc
    14761 aggaagtgct gggcaagcgc ctgacgcctt tcgaccgcgc tatcgatatg cacatttcca
    14821 acctgcgtcg taaactgccg gatcgtaaag atggtcaccc gtggtttaaa accttgcgtg
    14881 gtcgcggcta tctgatggtt tctgcttcat gataggcagc ttaaccgcgc gcatcttcgc
    14941 catcttctgg ctgacgctgg cgctggtgtt gatgttggtt ttgatgttac ccaagctcga
    15001 ttcacgccag atgaccgagc ttctggatag cgaacagcgt cagggtctga tgattgagca
    15061 gcatgtcgaa gcggagctgg cgaacgatcc gcccaacgat ttaatgtggt ggcggcgtct
    15121 gttccgggcg attgataagt gggcaccgcc aggacagcgt ttgttactgg tgaccaccga
    15181 aggccgcgtg atcggcgctg aacgcagcga aatgcagatc attcgtaact ttattggtca
    15241 ggccgataac gccgatcatc cgcagaagaa aaagtatggc cgcgtggaac tggtcggtcc
    15301 gttctccgtg cgtgatggcg aagataatta ccaactttat ctgattcgtc cggccagcag
    15361 ttctcaatcc gatttcataa acttactgtt tgaccgcccg ctattactgc tgattgtcac
    15421 catgctggtc agtacgccgc tgctgttgtg gttggcctgg agtctggcaa aaccggcgcg
    15481 taagctgaaa aacgctgccg atgaagttgc ccagggaaac ttacgccagc acccggaact
    15541 ggaagcgggg ccacaggaat tccttgccgc cggtgccagt tttaaccaga tggtcaccgc
    15601 gctggagcgc atgatgacct ctcagcagcg tctactttct gatatctctc acgaactgcg
    15661 caccccgctg acgcgtctgc aactgggtac ggcgttactg cgccgtcgta gcggtgaaag
    15721 caaggaactg gagcgtattg aaaccgaagc gcaacgtctg gacagcatga tcaacgatct
    15781 gttggtgatg tcacgtaatc agcagaaaaa tgcgctggtt agcgagacca tcaaagccaa
    15841 ccagttgtgg agtgaagtgc tggataacgc ggcgttcgaa gccgagcaaa tgggcaagtc
    15901 gttgacggtt aacttcccac ctgggccgtg gccgctgtac ggcaacccga acgccctgga
    15961 aagtgcgctg gaaaacattg ttcgtaatgc tctgcgttat tcccatacga agattgaagt
    16021 gggctttgcg gtagataaag acggtatcac cattacggtg gacgacgatg gtcctggcgt
    16081 tagcccggaa gatcgcgaac agattttccg tccgttctat cggaccgatg aagcacgcga
    16141 tcgtgaatct ggcggtacag gtttggggct ggcgattgtt gaaaccgcca ttcagcagca
    16201 tcgtggctgg gtgaaggcag aagacagccc gctgggcggt ttacggctgg tgatttggtt
    16261 gccgctgtat aagcggtcat aacgtcaacc ttcaggtaaa aaaatgcctg atgcactacg
    16321 cttatcaggc ctacaaaacc tgttgaattt atgggttttg taggctggat aaggcgttta
    16381 cgccgcatcc ggcatttgag caggatgcct gatgcgacgc tgatagcgtc ttatcaggcc
    16441 tacactccgg ggttattttc cccacaaacg gcgggaaaaa tcttcgatct tgccgctcag
    16501 tcggcgcttt tgcatcgttc gcgtccagct tttcgataac cctgcaacgg agagtaaacg
    16561 gtgatactga tcgtcatcaa acggcatatg ccatgcgatg gcggcagcct cctgcacggt
    16621 cacatcgctg acacgggaaa ccaactccag tggcgcatca gcagatacca accctggtgc
    16681 aattacgcta tacaaccacc ccactttacc cgtgttttgc atcaactgcg ctatatcgct
    16741 gatatcaaaa tggtaattga gtttatagca aggtgagcgt ggctggctga cctgaattaa
    16801 tgcctctccc cagcggaaaa tatcaccaat ataaacatta ctttccgtca gaccgtcggt
    16861 tgagagattt tcgccaaacg caggcgcaac aaacagctcc gcctgttccg gaaattcccg
    16921 cgcccagtag agataatgct cacgaggata atgacacagc gctctgtctg gcccgccgtg
    16981 gatctttttc tccgcctgtt cgtcaccttc cagccccagg tccgtcagca tcaactcacc
    17041 atcaacctgg attttggcaa ttgcgctggg tttgccttcg ggataagcct gaatcttgcc
    17101 tgtgtataca tcaaccggat atcgcatctg ttccctctcc acgagaaatt tccccattag
    17161 accatattta ttttatgtca ggcgtgctgt tttcgcggta agtatccagg cagaaacgca
    17221 attgaaaacc ggacgaacgt tagttcatcc ggctgtgggg attaaggaag ctggtttatt
    17281 tcaccgtacc taaaatttcg attttcgccg ctctggcttt gactttacgt gaccagatag
    17341 aggtaagaat tggcaccaga atcgaagtca caatgaccgc cgtcgctacc agcgaagttg
    17401 ctgccggagc cataggttta aacgcaggca ccatttctgc aatcagcaca ggtgtcgcta
    17461 ccgcggcccc agcggaactg gaagcggcaa ttccggcagt gccatcgcca ccgccaatca
    17521 atttatcggc gataatcaac ggaataccgg tcacgataat tactgccaca cccaacagga
    17581 tccccagcaa acctgtctgg gcaattacag tcaaatcaat ggtattgccc agtgcgaagg
    17641 caaagaatgg aatcagcgtc tgcaccgctt tgctgaaaaa ttctcgtaac tcagggtcaa
    17701 ggttccccag ggcaaagccc accaggaacg gcaatactgc gccgacgaaa acatgcggtt
    17761 caaacgaggc aatcccggca gtgcccagaa taatcatcgt catgagcggc ccggactcca
    17821 acgacatcaa cacaaatgcc ccagcttctt cttttgtgcc gtactgctgc atgatggaag
    17881 cgtaaagtcc gccgttggtc atatccatcg ccgccaccag cgccaacgtt gaaagtccgg
    17941 caaaaaatcc aacttcaaca ccatgttccg gaataatgcg cgaggcaatt gccgcaacca
    18001 cccacgcgac ggcaatttta gttaccacca gcgtaccgga tttacgcagt accgttcccg
    18061 tcgcgcttaa ttttattgac gcccccatgc aaaaaaacca caccgccaga atgggcaccg
    18121 taccggtaat catcccgttg gtgaatgatc caaaatattt ccccgccccc ggcgagaagg
    18181 tgtggcacag tgcgccaagg aatagcggga cgagcatcat cccccccggg attttctcaa
    18241 tcgagcgttt tatctgcatt tccatcacct gtcggcatat ttttaagggc tgatgcgtca
    18301 ttcctcaacg gagcatcagt gttgatggaa acgaagataa acattcattt gatcaataaa
    18361 agtgatcaaa accacatcaa ttgaaacgat gttttatttt tatcggatcg ttgtttttat
    18421 tttgaaagtg atcacaaaaa aaccaccgcc gttggcgatg gttcattttt taagctgcaa
    18481 tgcggcgtaa acgcctcatt gcagcaggcg tcaaatgatt attttttcgc cgcgaaacgt
    18541 gccgctgctt cgtcccagtt caccacgttc cagaactctt taatgtagtc cggacggcgg
    18601 ttctggaatt tcaggtagta agcatgttcc cacacatcca ggcccacaat cgggaagccg
    18661 gaagcgccag aaatggcttc gcccatcagc ggagagtcct ggttagcagt agaaaccacc
    18721 gccagtttat cgcctttttg caccagccat gcccagccgg aaccaaagcg ggaagctgcc
    18781 gctttttcaa attctgcttt gaaattatca acggaaccga aatcacgttc gatagccgct
    18841 ttcaggtcgc cctgcagggt ggtgcctttt ttcagacctt tccagaacag actgtggtta
    18901 gcgtgaccgc cagcgttatt gcgcagtacg gttttcttgt ctgctggcag ctggtccagt
    18961 ttggtgatca gctcttcaac cggcaggtta gcgaattctg gcaggctttc cagcgccgca
    19021 ttggcgttgt taacgtaggc ctgatggtgt ttggtgtggt ggatttccat ggtctgctta
    19081 tcgaagtgcg gttccagggc atcgtaagca tacggcaggg atggcagggt ataactcata
    19141 ttcatctcca gtgtggtcgg gcggccgatt gttaatgccg cgtaagcagt tggttcatta
    19201 tagttaatta aatgatattg aaaatgatta tcaatgccgt acttttcata agggtatggt
    19261 tttgcaggaa aatgcccaag atgtgaagca aatcacccac ttaatgccgt gattgccagt
    19321 aaatcggcag cggcggcaac aggcgaaagg ttaatcgaca gctcaatttt tacactcatc
    19381 tcgtcggaga tgtgacgcga cgaaaaatga tgaggataag aagatgagta acgcgattac
    19441 gatggggata ttttggcatt tgatcggcgc ggccagtgca gcctgttttt acgcgccgtt
    19501 caaaaaagta aaaaagtggt catgggaaac catgtggtca gtcggtggga ttgtttcgtg
    19561 gattatcctg ccgtgggcca tcagcgccct gttactaccg aatttctggg cgtattacag
    19621 ctcatttagt ctctctacgc tgctgcctgt ttttctgttc ggcgctatgt gggggatcgg
    19681 taatatcaac tacggcctga ccatgcgtta tctcggcatg tcgatgggaa ttggcatcgc
    19741 cattggcatt acgttgattg tcggtacgct gatgacgcca attatcaacg gcaatttcga
    19801 tgtgctgatt aataccgaag gcggacgcat gacgttgctc ggcgttctgg tggcgctgat
    19861 tggcgtaggg attgtaactc gcgccgggca gttgaaagag cgcaagatgg gcattaaagc
    19921 cgaagagttc aatctgaaaa aagggctggt gctggcggtg atgtgcggca ttttctctgc
    19981 cgggatgtcc tttgcgatga acgccgcaaa accgatgcat gaagccgctg ccgcgctggg
    20041 cgtcgatccc ctgtatgtcg ctttgccaag ctatgttgtc atcatgggcg gcggcgcaat
    20101 catcaacctc ggcttctgct tcattcgtct ggccaaagtg aaagatttgt cgctaaaagc
    20161 cgacttctcg ctggcaaaac cgctgatcat tcacaatgtg ttactctcag cactgggcgg
    20221 gttgatgtgg tatctgcaat tctttttcta tgcctggggc cacgcccgca ttccggcgca
    20281 gtatgactac atcagctgga tgctgcatat gagcttctat gtattgtgcg gcggtatcgt
    20341 cgggctggtg ctgaaagagt ggaacaatgc aggacgccgt ccggtaacgg tgttgagcct
    20401 cggttgtgtg gtgattattg tcgccgctaa catcgtcggc atcggcatgg cgaattaatc
    20461 tttctgcgaa ttgagatgac gccactggct gggcgtcatc ccggtttccc gggtaaacac
    20521 caccgaaaaa tagttactat cttcaaagcc acattcggtc gaaatatcac tgattaacag
    20581 gcggctatgc tggagaagat attgcgcatg acacactctg acctgccgca gatattgatt
    20641 gatggtcatt ccagtctgct ggcgaaattg ctgacgcaaa acacgctcac tgcatgatgc
    20701 ctcatcacaa aatttatcca gcgcaaaggg acttttcagg ctagccgcca gccgggtaat
    20761 cagcttatcc agcaatgttt cgctggatgt tggcggcaac gaatcactgg tgtaacgatg
    20821 gcgattcagc aacatcacca actgcccgaa cagcaactca gccatttcgt tagcaaacga
    20881 cacatgctga ctactttcat gctcaagctg accgataacc tgccgcgcct gcgccatccc
    20941 cacgctacct aagcgccagt gtggttgccc tgcgctggcg ctaaatcccg gaatcgcgcc
    21001 ctgccagtca agattcagct tcagccgctc cgggcaataa ataatattct gcaaaaccag
    21061 atcgttaacg gaagcgtagg agtgtttatc gtcagcatga atataaaaga gatcgccacg
    21121 ggtaatgcga taagggcgat cgttgagtac atgcagacca ttaccgcgcc agacaatcac
    21181 cagctcacaa aaatcatgtg tatgttcggc aaagacatct tgcggataac ggtcagccac
    21241 agcgactgcc tgctggtcgc tggcaaaaaa atcatctttg agaagtttta actgatgcgc
    21301 caccgtggct acctcggcca gagaacgaag ttgattattc gcaatatggc gtacaaatac
    21361 gttgagaaga ttcgcgttat tgcagaaaac catcccgtcc ctgacgaata tcacgcggtg
    21421 accagttaaa ctctcggcga aaaagcgtcg aaaagtggtt actgtcgctg aatccgcagc
    21481 gataggcgat gtcagtaacg ctggcctcgc tgtggcgtag cagatgtcgg gctttcatca
    21541 gtcgcaggcg gttcaggtaa cgctgaggcg tcagtcccgt ttgctgctta agctgccgat
    21601 gtagcgtacg caatgaaaga gaaaattgag ccgccactgc atcccaattc acctcatcgg
    21661 caaaatggtc ctccagccag gccagaagca agttgagacg tgatgcgctg ttttccacgc
    21721 tctcctgcaa actgctttta cgcagtaaga gcagtaattg cataaacaga atttcacgac
    21781 tggcggtcga gggtaaatca tttccctctt cttgttgttc caactgtgca accagttggc
    21841 gcacctgctg taatacgcaa tggttaacgc gccagtgaga cggatactgc ccatcctgct
    21901 cttgtggcag caactgattc agcccggcga gaaactgaaa tcgatccggc gagcgataca
    21961 gcacattggt cagacacaga ttatcggtat gttcatacag atgccgatca tgatcgcgta
    22021 cgaaacaaac cgtcccaccg gtgatggtat agggctgccc attaaataca tgaatacccg
    22081 tgccatgttc gacaatcaca atttcatgaa aatcatgatg atgttcagga aaatccgcct
    22141 gcgggagccg gggttctatc gccacggacg cgttaccaga cggaaaaaaa tccacactat
    22201 gtaatacggt catactggcc tcctgatgtc gtcaacacgg cgaaatagta atcacgaggt
    22261 caggttctta ccttaaattt tcgacggaaa accacgtaaa aaacgtcgat ttttcaagat
    22321 acagcgtgaa ttttcaggaa atgcggtgag catcacatca ccacaatgaa gcaaattgtg
    22381 aacatcatca cgttcatctt tccctggttg ccaatggccc attttcctgt cagtaacgag
    22441 aaggtcacga attcaggcgc tttttagact ggtcgtaatg aaattcagca ggatcacatt
    22501 atgacctttc gcaattgtgt cgccgtcgat ctcggcgcat ccagtgggcg cgtgatgctg
    22561 gcgcgttacg agcgtgaatg ccgcagcctg acgctgcgcg aaatccatcg ttttaacaat
    22621 ggcctgcata gccagaacgg ttatgtcacc tggaatgtgg atagcctgga aagtgccatt
    22681 cgccttggat taaacaaggt gtgcgaggaa gggattcgta tcgatagcat tgggattgat
    22741 acctggggcg tggactttgt gctgctcgac cagcacggtc agcgcgtggg tctgcccgtt
    22801 gcttaccgcg atagccgcac caatggccta atggcgcagg cacaacagca actcggcaaa
    22861 cgcgatattt atcaacgtag cggcatccag tttttgccct tcaatacgat ctatcagcta
    22921 cgtgcactga cagagcagca accagaactt attccacaca ttgctcacgc tttgctgata
    22981 ccggattact ttagttatcg cctgaccggc aagatgaact gggaatatac caacgccacg
    23041 accacgcaac tggtcaatat caatagcgac gactgggacg agtcgctact ggcgtggagc
    23101 ggtgccaaca aagcctggtt tggtcgcccg acgcatccgg gtaatgtcat aggtcactgg
    23161 atttgcccgc agggtaatga gattccggtg gtcgccgttg ccagccatga taccgccagc
    23221 gcggttatcg cctcgccgtt aaacggttca cgcgccgctt atctctcttc tggcacctgg
    23281 tcattgatgg gcttcgaaag ccagacgcca tttaccaatg acacggcgct ggcagccaat
    23341 atcaccaacg aaggcggggc ggaaggtcgc tatcgggtgc tgaaaaatat tatgggctta
    23401 tggctgcttc agcgagtgct tcaggagcgg caaatcaacg atcttccggc gcttatcgcc
    23461 gcaacacagg cacttccggc ctgccgcttc atcatcaatc ccaatgacga tcgctttatt
    23521 aatcctgacg agatgtgcag cgaaattcag gctgcgtgtc gggaaacggc gcaaccgatc
    23581 ccggaaagtg atgctgaact ggcgcgctgt attttcgaca gtctggcgct gctgtatgcc
    23641 gatgtgttgc atgagctggc gcagctgcgt ggtgaagatt tctcgcaact gcatattgtc
    23701 ggcggcggct gccagaacac gctgctcaac cagctgtgtg ccgatgcctg cggtattcgg
    23761 gtgatcgccg ggcctgttga agcctcgacg ctcggcaata tcggcatcca gttaatgacg
    23821 ctggatgaac tcaacaatgt ggatgatttc cgtcaggtcg tcagcactac cgcgaatctg
    23881 accaccttta cccctaatcc tgacagtgaa attgcccact atgtggcgca gattcactct
    23941 acacgacaga caaaggagct ttgcgcatga ccactcaact ggaacaggcc tgggagcttg
    24001 cgaaacagcg tttcgcggca gtagggattg atgtcgagga ggcactgcgc caacttgatc
    24061 gtttacccgt ttcaatgcac tgctggcagg gcgatgatgt ttccggtttt gaaaacccgg
    24121 aaggttcgct gaccggtggt attcaggcta ctggtaatta tccgggcaaa gcgcgtaatg
    24181 ccagcgagct gcgtgccgat ctggaacagg ctatgcggct gattccgggg ccaaaacggc
    24241 ttaatttgca tgccatttat ctggagtcag acacgccagt ctcacgtgac caaatcaaac
    24301 cagagcactt caaaaactgg gttgaatggg cgaaagccaa tcagctcggt ctggatttta
    24361 acccctcctg tttttcacat ccgctaagcg ccgatggctt tacactttcc catgccgacg
    24421 accgcattcg ccagttctgg attgaccact gtaaagccag ccgccgtgtt tcagcctatt
    24481 ttggtgagca actcggcaca ccgtcggtga tgaacatctg gatcccggat ggcatgaaag
    24541 atatcaccgt tgaccgtctc gccccgcgtc agcgtttgct ggcagcactg gatgaagtga
    24601 tcagcgagaa gctaaaccct gcgcaccata tcgacgccgt tgagagcaaa ttgtttggca
    24661 ttggcgcgga gagctacacg gttggctcca atgagtttta cctggggtat gccaccagcc
    24721 gccagacggc gctgtgcctg gacgccgggc atttccaccc gactgaagtg atttccgaca
    24781 agatttccgc cgccatgctg tatgtgccgc agttgctgct gcacgtcagc cgtccggttc
    24841 gctgggacag cgatcacgta gtgctgctgg atgatgaaac ccaggcgatt gccagtgaga
    24901 ttgttcgtca cgatctgctc gaccgggtgc atatcggcct cgacttcttc gatgcctcta
    24961 tcaaccgcat tgccgcgtgg gtcattggta cacgcaatat gaaaaaagcc ctgctgcgtg
    25021 cgttgctgga acctaccgct gagctacgca agctggaagc ggcgggcgat tacactgcgc
    25081 gtctggcgct actggaagag cagaaatcgt tgccgtggca ggcggtatgg gaaatgtatt
    25141 gtcagcgtca cgatacgcca gcgggtagcg aatggctgga gaacgtgcgg acttatgaga
    25201 aaaaaatttt gagtcgccgc gggtaaacac tgccggatgc ggcacaagtg ccttatccgg
    25261 cctacgggtc ggcaatagtt gtaggcctga taagacgcga cagcgtcgca tcaggcattg
    25321 attgccggat gcggcacgag tgccttatcc ggcctacggg tcagcaacag ttgtaggcct
    25381 gataagacgc gacagcgtcg catcaggcat tgattgccgg atgtggcgcg agtgccttat
    25441 ccggcctaca ggtcgtgcat ccgacaacac cgaattaaca ggaacacaga acatgcaaaa
    25501 cataacccag tcctggtttg tccagggaat gatcaaagcc accaccgatg cctggctgaa
    25561 aggctgggac gagcgcaacg gcggcaacct gacgctgcgc ctggatgacg ccgatatcgc
    25621 accatatcac gacaattttc accaacaacc gcgctatatc ccgctcagcc agcccatgcc
    25681 tttactggca aatacaccgt ttattgtcac cggctccggc aaattcttcc gtaacgtcca
    25741 gcttgatcct gcggctaact taggcatcgt aaaagtcgac agcgacggcg cgggctacca
    25801 cattctttgg gggttaacca acgaagccgt tcccacttct gaacttccgg ctcactttct
    25861 ctcccactgc gagcgcatta aagccaccaa cggtaaagat cgggtgatca tgcactgcca
    25921 cgccaccaac ctgatcgccc tcacctatgt acttgaaaac gacaccgcgg tcttcactcg
    25981 ccaactgtgg gaaggcagca ccgagtgtct ggtggtattc ccggatggcg ttggcattct
    26041 gccgtggatg gtgcccggca cggacgaaat cggccaggca actgcacaag agatgcaaaa
    26101 acattcgctg gtgttgtggc ccttccacgg tgtgttcggc agcgggccga cgctggatga
    26161 aaccttcggt ttaatcgaca ccgcagaaaa atcagcacaa gtattagtga aggtttattc
    26221 gatgggcggc atgaaacaga ccatcagccg tgaagagttg atagcgctcg gccagcgttt
    26281 cggcgttaca ccactcgcca gtgcgctggc gctgtaagga gcaaacatga tccgcaaagc
    26341 ctttgtcatg caggtaaacc ccgacgccca cgaagagtat cagcgtcggc ataatcccat
    26401 ctggccggaa ctggaagcag tgctgaaatc tcacggtgcg cataactacg ccatctatct
    26461 cgacaaagcg cgtaatctgc tatttgccac gatagagatt gaatctgaag agcggtggaa
    26521 tgcggttgcc agtacagatg tttgccaacg ttggtggaaa tatatgaccg acgttatgcc
    26581 cgctaatgcg gataacagcc cagtcagtag cgaactgcaa gaagtgtttt acctgcctta
    26641 atgagttgcg gtgccggaaa atatccagca ccgccctttc atcagaagaa gtatttaaag
    26701 cgaacgcgtg cgccgtaacg gtcatcacta tcgtcgccgt gtatcttatc gccgtcgcta
    26761 tccagaatgg agtaatacgt gccgaggtaa atattaaagt tctccatatc catcacatta
    26821 gcgaactgat aagacgcatg aatggtgtga atgttgtatg ttccttcatc atcaatccag
    26881 caatcgttat cacaaaccac gccactaaat tcatcaatct tattatgtgc gtagatataa
    26941 cccagctcga aacgtttcca cagcgcgtta atcccagcgg tgaaatcttt ctcattatta
    27001 gcatctaaat aggcggtatt aagattaacc acgatgccat tttccggatc ggttttcagg
    27061 ccattccagg tcatgctcat gccataaccg gtacgatcgg actgatcgac aaaattaccc
    27121 ttgctatcgg tataaccata agcattattt accacgttcg cttccatcgc tgcggaaacg
    27181 gtgaattctt ccgtcggcga ccaggcaatt accggacgca gataagcaac atttttctgc
    27241 tgttccatat cgcgtccatg ataattaccg tcgttatata aagatgttcc gtcttccagt
    27301 aacgtgttta attcaaaata ccagttatcg agttgtttgc tgacgaggaa attaccgcca
    27361 gcgttagaac gcccgcggcc ctctttcatc atatagatat aaccgctgcc atcgtcataa
    27421 agatcgttcg cagtattacc ggaatgttca acaaaggtat cctgattcag cgggaacata
    27481 tcgtaggctt caaaacggcc tactttgacc ttccagtcgt tttctttgcc aaagaagaaa
    27541 accgcatcat cgatatttac tgaaccgtgc atatccccca gcggttgtgc ggagaaccca
    27601 gcgaaatagc cattatccag ttttcgcata ccatcaaaac ctaacagaat acgaccattg
    27661 agattccact gttcattagt gggatcgcta ttcacatcag cgttggtcat tgccagcagg
    27721 ccatgattac tttccgcatc catattaaat tctacgtcac cgtagatttt taaatcgcca
    27781 taccctgaaa gcaggagatt aggcggggtg gcgtttttct tctctgactc cgtcgttgat
    27841 tgaccgttta ccggcgtgtt gccctgtgcg gttttaattt cgcggatctc ggcggcttgt
    27901 tgtgtctgaa gctgtttaac ctgcccctct gcttttgctg cccgcatttc tgccgcttcc
    27961 aggcgttctt ccagcaatgc catgcgttgt tccagcgtta aatgctgtgt ttttgccata
    28021 ccggtactac atgccaataa taaaccgatg gctaaagata atgtcgattt tttcattatt
    28081 tacgttccct gaaataaagg agaccctacg ctttccaaaa ggaatacgta tatagagaaa
    28141 tataaggtgt gcactttcga atttttaatc caacttcagc aggccgatgg atagtatccc
    28201 gccatataat atgagtaaat ccgctgattt cctggaacgt gaggaatata acaatagtgc
    28261 cgtttttaac taaatatcgt aaaaaatatt agatatgatt cacgctgact cataagccac
    28321 aaatataaat aacgcttaaa caaattatct gagatatttt aacattcaca aaatcattaa
    28381 ataatgatac tttattcaca aaatttatcc ttcactctgc tttatattgt tacgacttcg
    28441 tgacatatcc gtgctcatca caaacccgcc ccgcgattac aattaactga aatatttcat
    28501 cgaccatttc gttgtaatcg cataacgctc gtggaaatga gtcttcggcc atccagcttg
    28561 agtttgcgtc ctgaagttgc tctttatccc agtcagagta cgggacttta tctctgatgc
    28621 ggcgaacgta ttttttagcc tcgagttgat actggcctgc cgaattaata aacgagaaat
    28681 tcatgccgct tttatccgct tctttggctt gcgccaccag cgtttccagt tcagacactt
    28741 tcttcattgc cgcttctgca tcaaacttat cttgcgatat caggttatta atttgtttcg
    28801 ctgaaatcat gactgccaga gagtagtagt ggaatgtttt ccctttcgca aacgcatcgt
    28861 ctttataatt ttcctgggtg taatatttat ccatttcgtt aatggtatta cccaacgcta
    28921 cggcagcatc aatataactc accgccacgc catcaatagg ttgcagcgca ggcattaacg
    28981 ccactacacg cgttttgttt ataaaaaaat aacaaaattc acgaaatgaa taagtcctgt
    29041 aatttaatat atatcgcagg acttatttta attaattgct caaacgctgc ggatgggtat
    29101 aaaccgtcgc ccgacccggt ttacaaaagc ccaccagcgt cagattacag cgctcagcca
    29161 cttctacagc aagtgtggtc gcggcagaca ccgcaaacaa aatctctacg ccgcacatcg
    29221 ccgacttttg caccatttca taactggcac ggctggaaac cagcaccgca ccttgctgcc
    29281 agctttcccc ttcttgtgat cggcggccta acagtttgtc cagcgccaca tggcgaccca
    29341 cgtcttcatg cccgccgacc agttcgccag atggcaacat ccatgcagcg gcgtgagtac
    29401 aaccagtcag ttgccccact ggctggaaat cattgagatg acgtaatgca tcatccagtt
    29461 tgttgagatc aaacgtctgg gtgaacggca gcggctgcac cggtttaccg atatcgttaa
    29521 gctgttctac accgcatacg ccacagcccg tacgtcccgc cagcgcccgg cgacgttcct
    29581 tcaaccccat aaagcggcgg ctggaaagct caatttgtac ttccaggcca ttacaggaag
    29641 gaacgacatc catgccgaag atatcgcgcg ggctttcgat aattccttcg gaaagcgaaa
    29701 aaccgagcgc aaagtactca aggtctttgg gcgacgccat catcaccacg tgcgaaatgc
    29761 cgttgtagac cagcgcaacg ggaacttctt ccgccacctc atctaaccgt gggtgttgta
    29821 aatcatcacg ccgccataac tcaatttgac gaacacctgt gatatttgtc acattctcga
    29881 tttctttttg ctgtgttttt ttcactttct attaaccaga taagaacaca cacaccaaca
    29941 ttatggtatt ctgttacaaa cccttcctgg atggagggaa attgagccaa ttctggacct
    30001 ttgcggcccc ttccgcaaag aaaaataact cccactccct gcacacgcag caagcgaatg
    30061 taaatgggac gtgacaatgt cgaaacaagg agcaatccat gcaggtcagc agaaggcagt
    30121 tctttaagat ctgcgctggc ggtatggcag gcaccacggc agcggcactg ggttttgcac
    30181 ccagcgtagc actcgcggaa acccggcagt ataaactgct gcgcacccgc gaaacccgta
    30241 atacctgcac ctattgttcc gtaggctgtg ggctgttgat gtacagcctc ggtgacggag
    30301 caaaaaacgc caaagcatct atcttccata tcgaaggtga cccggatcac ccggtcaacc
    30361 gcggagcact ttgtccgaaa ggcgctggcc tggtggattt catccactcc gaaagccgtc
    30421 tgaagtttcc ggaataccgt gcgccaggtt ctgataaatg gcagcaaatc agttgggaag
    30481 aggcgtttga tcgcatcgcc aaactgatga aagaagaccg cgatgcaaac tacattgcgc
    30541 aaaacgccga aggcgtgact gttaaccgct ggctctccac cgggatgctg tgtgcttccg
    30601 cgtcgagcaa cgaaaccggc tatttaacgc aaaaattctc ccgcgcgctg ggtatgctcg
    30661 cggtcgacaa ccaggcgcgt gtctgacacg gaccaacggt agcaagtctt gctccaacat
    30721 ttggtcgcgg tgcgatgacc aaccactggg tcgacatcaa gaatgccaac ctcgtcgtgg
    30781 tgatgggcgg taacgccgct gaagctcacc cggtcgggtt ccgctgggcg atggaagcca
    30841 aaattcacaa cggcgcgaag ctgattgtga tcgatcctcg ctttacgcgt acagcggcgg
    30901 tggctgacta ctatgcccct atccgttccg gtactgacat tgctttcctg tcaggcgtat
    30961 tgctgtacct gctgaacaat gaaaaattca accgcgaata caccgaagcc tataccaacg
    31021 ctagcctgat cgtgcgtgag gattacggct ttgaagatgg cctgttcacc ggctacgacg
    31081 cggaaaaacg caagtacgat aagtccacct ggacttacga actggacgaa aacggcttcg
    31141 ccaaacgcga tactaccctg caacatccac gttgcgtgtg gaacttgctg aaacagcacg
    31201 tttcccgcta cacgccagat gtggttgaaa acatctgcgg tacgccaaaa gacgcattcc
    31261 tgaaagtctg cgaatacatc gcagagacca gtgctcacga taaaactgcc tcgttccttt
    31321 acgccctcgg ctggacgcaa cactccatcg gtgcgcagaa catccgtacg atggcgatga
    31381 tccagttgct gctcggcaat atggggatgg ctggcggcgg cgttaacgcc ctgcgcggtc
    31441 actccaatat tcaggggctg acggacctgg ggctgctgtc gcagagtctg ccaggttaca
    31501 tgacgctgcc aagcgagaag cagaccgatc tgcaaactta ccttaccgcc aacacgccga
    31561 aaccactgct ggaaggccag gttaactact ggggcaacta cccgaaattc ttcgtctcta
    31621 tgatgaaggc cttctttggt gataaagcga cggcggaaaa tagctggggc tttgactggt
    31681 tgccgaagtg ggataaaggc tacgacgtcc tgcaatactt cgagatgatg aaagagggca
    31741 aggtcaatgg ctatatctgc cagggcttta accctgttgc ctcattcccg aacaaaaaca
    31801 aagtgatcgg ctgtctgtcg aagctgaaat tcctcgtgac tatcgacccg ctgaacactg
    31861 aaacctctaa cttctggcag aaccacggtg aactgaacga agttgactcg tcgaagatcc
    31921 agaccgaagt gttccgtctg ccatcgacct gcttcgcgga agagaacggt tcaatcgtta
    31981 actctggtcg ctggttgcag tggcactgga aaggtgcgga cgccccgggg attgcgctga
    32041 ctgatggcga gatcctctcc ggtatcttcc tgcgcttgcg caagatgtat gccgaacagg
    32101 gtggcgcgaa cccggaccag gtgctgaaca tgacctggaa ctacgccatc ccgcatgagc
    32161 cgaagtcgga agaagtggcg atggagagca acggtaaggc gctggccgat attaccgatc
    32221 cggcaaccgg tgcggttatt gtcaagaaag gccaacaact tagctcgttc gctcaactgc
    32281 gcgatgacgg tacaacctcc tgtggctgct ggattttcgc cggtagctgg acgccagaag
    32341 gcaaccagat ggcgcgtcgt gataacgccg atccgtctgg cctcggtaac acgctgggct
    32401 gggcatgggc atggccgctt aaccgccgca ttctgtataa ccgcgcctcc gcagatccgc
    32461 agggtaaccc gtgggatccg aagcgtcagt tgctgaaatg ggacggcact aagtggaccg
    32521 gctgggatat tccggactac agcgcagcgc ctccgggcag tggcgtcggg ccgtttatca
    32581 tgcagcagga aggcatgggg cgtctgtttg ccctcgataa gatggcggaa ggtccgttcc
    32641 cggaacacta cgagccgttt gaaacgccgc tgggaactaa cccgctgcat ccaaacgtta
    32701 tctcgaatcc ggcggcgcgt atctttaaag acgatgccga agcattgggg aaagccgata
    32761 agttcccgta tgtcggaacc acctatcgtc tgaccgagca cttccactac tggaccaaac
    32821 acgcgctgtt gaacgcgatt ttgcaaccag agcagtttgt ggaaatcggg gagtcgctgg
    32881 cgaataaact tggcattgcc cagggcgata ctgtgaaagt ctcctccaac cgtggctata
    32941 tcaaagccaa agcggtagtg accaaacgta ttcgcacgct gaaagcaaac ggcaaagata
    33001 tcgataccat cggtattccg attcactggg gctatgaagg tgttgcgaaa aaaggcttta
    33061 ttgccaatac gttgacgcca ttcgtcggtg atgcgaacac gcagacgccg gagtttaagt
    33121 ccttccttgt gaatgtggaa aaggtgtaac ggagacgaca tatggcttat caatcgcaag
    33181 atatcattcg tcgttccgcg actaacggtc tgacccccgc gcctcaggcg cgggacttcc
    33241 aggaagaagt ggcgaaactc atcgacgtta ccacctgtat cggctgtaaa gcctgtcagg
    33301 tggcgtgttc agagtggaac gacattcgcg ataccgtcgg caataacatt ggggtgtatg
    33361 acaaccccaa tgatttaagt gccaaatcgt ggacggtgat gcgattctcg gaagtggagc
    33421 agaacgacaa actggaatgg ctgatccgca aagacggctg tatgcactgt tccgatccag
    33481 gctgcctgaa agcatgcccg gcggaagggg caattattca gtatgccaat ggtatcgtcg
    33541 acttccagtc cgagcagtgc atcggctgcg gttattgcat cgcagggtgc ccgttcaacg
    33601 tgccacgcct caacccggaa gacaaccgcg tctacaaatg tacgttgtgc gttgaccgcg
    33661 tggtggttgg gcaagaaccg gcctgcgtga agacctgccc aacgggcgcg attcacttcg
    33721 gtacgaaaga gtcgatgaaa acgctggcga gcgagcgcgt ggcggagctg aaaacccgcg
    33781 gttacgacaa tgcgggtctg tacgatccgg caggcgtcgg tggtacacac gttatgtacg
    33841 tactgcacca tgctgacaag ccaaatctgt atcatggctt gccggagaac ccggaaatca
    33901 gcgaaaccgt gaaattctgg aaaggcatct ggaaaccact cgcagctgtt ggctttgcgg
    33961 ctaccttcgc agccagtatc ttccactacg tgggtgtcgg tccgaaccgt gcggatgagg
    34021 aagagaataa tctgcacgaa gagaaagacg aggagcgcaa atgaaacgac gtgacaccat
    34081 cgtgcgctac accgcgccgg aacgtatcaa ccactggatc accgccttct gcttcatcct
    34141 ggcggcggtg agcgggctgg gctttttgtt cccgtccttc aactggttga tgcaaatcat
    34201 gggcacaccg cagctggcgc gaattctgca tccgtttgtc ggcgtggtta tgtttgcctc
    34261 gttcatcatc atgtttttcc gttactggca tcacaaccta atcaatcggg atgatatctt
    34321 ttgggcgaag aatattcgta agatcgtcgt caacgaggaa gtaggtgaca ccgggcgtta
    34381 taacttcggt cagaaatgcg ttttctgggc ggcgattatt ttcctggtcc tgttgctggt
    34441 gagcggcgtg attatctggc gtccttattt tgcgcctgct ttctcaatcc cggtgatccg
    34501 attcgcgtta atgctgcatt catttgccgc agtggcgtta attgtggtta tcatggtgca
    34561 tatctacgcc gccctttggg tgaaaggcac gattaccgcc atggtggaag gatgggtgac
    34621 cagcgcatgg gcaaagaaac atcacccgcg ctggtaccgt gaggtccgca agacaacgga
    34681 aaagaaagct gaatgagtat tcgcataatc ccgcaagatg agctgggttc gagcgagaaa
    34741 cgtacggcgg atatgattcc gccgttattg ttccctcggc tcaagaattt atacaaccgc
    34801 cgcgccgagc gtctgcgcga gctggcagaa cataatccgc tgggtgatta cctgcgcttt
    34861 gctgcgctta tcgcccacgc ccaggaagtg gtgctgtacg accatccgct ggagatggat
    34921 ctgaccacgc gcattaaaga agccagcgca caaggcaagc ccccgctgga tattcacgtt
    34981 ctgccgcgtg ataagcactg gcaaaagctg ctgatggcgc tgattgctga gctgaaacct
    35041 gaaatgagcg gcccggcgct ggcagtgatt gagaatctgg agaaggcatc gactcaggag
    35101 ctggaagata tggccagcgc actgtttgcc tctgatttct cgtccgtcag cagcgataaa
    35161 gcgccgttta tctgggctgc gctgtcgctc tactgggcgc agatggctaa tctgatcccc
    35221 ggcaaagccc gcgctgaata cggcgaacaa cgtcaatatt gcccggtatg tggctctatg
    35281 ccggtgtcca gcatggtgca aattggcacc actcagggtc tgcgttacct gcactgcaac
    35341 ctgtgtgaaa ctgaatggca cgtagtgcgc gtaaaatgca gcaactgtga acagagcggc
    35401 aaactgcatt actggtcgct ggatgacgaa caggccgcga ttaaagccga aagctgcgat
    35461 gactgcggca cttacctgaa gattctttat caggaaaaag aaccgaaagt tgaagccgtg
    35521 gcagatgacc tcgcctctct ggtactggac gcgcgaatgg agcaagaagg ctatgcccgt
    35581 agttccatca acccgttcct gtttccgggt gaaggggagt aatctctgac gttttccggg
    35641 tggcgcaggt cgcccggatt acagttcata gggtgtgacg acactatctc tcgtattccg
    35701 cgttacctcc tcaagctatg ccgccagtgc ctgtttggcc tcaattttca cgctgagaaa
    35761 atcgataagg atatcgatat caaatagcca aatctttttg ccattaccat ttctcgcgca
    35821 gcttacgcag gtattcgaca ccatcttcct cacacccttg ccagatgcca ggaacactgg
    35881 ttcttgctgt ttgcgattga tttaccaggt attgatctac cgcttcccgt aataggtctg
    35941 cacgcggaag attacgctgc acctcaagat catcaagttg cttaatcacc tcattcgata
    36001 aatcgagtaa aattctgctc atatccatac ctgccagagg gttcataaat atctcgccaa
    36061 tatcattttg aatctatgga gagaaaagta cccttgtcga atctttaaag aaagcgcatt
    36121 tacgcatcac tttttatttt tgcgaggcgt tttccagata cgatgtaaca gttgcagtta
    36181 ttacgaaaac cagtaaaaaa tggaagtgaa aacagtcgtg tgaaaatttc tactctttct
    36241 gaatttactc tataaagttg cctttctcac atccaatagc ttaatgtcat ctaccaagaa
    36301 aaaacgataa gtcgtcaggg aacggaacag atataatgaa taaaaacgaa tcaatttctt
    36361 acaccgaaat gcaaaaattt tttgccagag aaattaagga agtaggcggt aggcccatca
    36421 cttctaagaa tttagagtta agtctgctac ccattcacgc cagggaaaac ctttctgcgc
    36481 cagaaatgcc gtggtatacc gaagttaatg atatctatat ggagttcaga cgctcaccat
    36541 tctggatggt tgccggttat gtattcctgg gatttatgct ttcactactt tccatctcga
    36601 tattatctat tgttgcattc tcattttatg agatgggctt taatagtgac ttgttatttc
    36661 tgtatctact tgcatttgtg cttggctgtt ttatattacc tggcgctgca aaaattgctt
    36721 ttttcacgcc acattatctt cctataagat ttaacagaaa aacacaaaaa atttatgttt
    36781 cagatttaat tattgaaggc aatatcttct ttggaaaaat aaaactcact tttcatgaat
    36841 atgactggaa agatgttgaa ggttgggagg tgagtagaca tttcagtaaa agtatgcctt
    36901 acaatggatt acatctggta gttaatagag aaaatgatat aaatgcactg cgacagacac
    36961 gcgtttatac aacccgtgca ccgtggagtg cacaagaaat ggcaagacaa aagaactata
    37021 tcccccaaat atggctttat tgccataatt atatggctta taaaactgtg tctggtgcaa
    37081 agaacaaacc acaaccattt atttttttaa gaaacaattg gctatttaaa tggccaaaag
    37141 aaatggataa acgttccaga agctcaaaga tactgtctga ataagcataa taatgaagga
    37201 tttcgactat gattaacaaa cttactcttc cttggccggt attattttta gaattttttg
    37261 tgcgagaagt tgcctttaag ggtaagggaa ttgttcgttc tacattacca gcagatgccc
    37321 atttttatac cggtgggtca aaagccctgc gttatcacct acaaccagga aaccaatggc
    37381 caaactatat atggcatgat gatataggtg atattgtacc gtttcctcta ccctcacttc
    37441 cgcttacatt taccgctaac cgacccacat ttaattccag agaattagcg gataaatgga
    37501 tgaaggataa tattcatacc gctgtcatca tggcggggga atttctgtct gctaatgaat
    37561 ggattcgccg caaaaaccag cttaaaacta gtgtacaccc tgcgtcagtt gcttctttcg
    37621 caccctatgg ctttaacatt aaccagtgtg atgacgatgg caatctttgg actaatttcc
    37681 cacgtcccca catcaaatta aaaatcgcac caggaaaaac agcttgtttt ctctgccgcc
    37741 gggaagagct tttatttggt tatgatgaag cacataatca ctaccagccg aatcttaatc
    37801 tggttttatt tgtgaaaaat catgggttgc ataaggatgt ttacctaaaa tctcatgacg
    37861 ataaaagtga atacgatagc agaatattat gtaacgaaaa atttaccact tatgatttcc
    37921 gtaaaaaccg gtccagatac agcttttgat agtttattat cctggatgat atcaggagcg
    37981 atatctataa agtttatgca ttccctgtga tcaatttttc ctgttagtga gcacaaattc
    38041 aatctgattg atgccagaat aaaggcatct ggcatgttga ttttatgttc cagaatgaca
    38101 aaacattgct gttaataagc acgactcttt ttgtcattcc tcatgccact taccctgttc
    38161 ttcaacacca actacctcac ccctttgcct gtcacttttt gccttacgca ccggaaattg
    38221 ctgacgctcc agatattgct ctaccgcttc gcgtaaaatt gcagagcgcg aaaccttacg
    38281 ccagccccga agcttgttca gccgtttaat tgcctcttct gataaatgaa gaaaaaccgt
    38341 attcatcgcc attgccacca ccttacatat attactcatt aatgtatgtg cgaaaattac
    38401 gccgaaaaat catttaaaaa aagcggattt ttgcatgtcg ttttgttttt gcgagactgc
    38461 atccaaagat aatgtaacag ttgcagttat ttcaattgtt actcaaaaat ggtttattac
    38521 ttttaattaa gcgggggcac atctacagaa aagaaacaac aaataataag gatgaattat
    38581 ggatgctata aatattttat attcaagaat atttttttga ttgggtcttc atttgcttca
    38641 tcaggatggt gtacccgaaa aagtcagcag ctttaccgca ccaggggtta aggtgaaatc
    38701 taccattcat aacgaccggt cagtgccgca ccaaccggtc tttaattgtt agtagtagta
    38761 aatttgtgga taacagtccg ggaaccagac gattccttcc ggatcatccc cctgcattac
    38821 ccgatgacat tggcgtcgat catctgcgcg acggcgaagc gtagtataga gccgcttcca
    38881 ttcatgatcg cccggtgtac tgtagtttac ccaacaatcc attgaagggt gacgccattt
    38941 acctgtaagt gttgggatcc ctgaatgctt atgcggcttc gctttaccat tacgatccct
    39001 atctttacgc gtattaaacg tggacatttt tagtctcctg ttaagagttc taaaaatgtg
    39061 cttccttaaa atagttcatc attttccctt aattcgcata gcgtgctttt gcacgaattt
    39121 ccgatacgcg gggaccatta tgatagcgtc gatgcccaca catccaacaa gaacaaatac
    39181 agggagtacg aaagcaaata cctgatgctt ttttgcttcc atcgcctgca gtgcgataac
    39241 gacagcggat tttttttaat cgcaccatat gatggcgacg ttcagcacga ttacgggtca
    39301 tagcaaaact cctgaacagg cggcactatg ccgctttcat aggagttctg aatgctggtg
    39361 ctttctgtat ggcataacca tgcctctaac ggttaagtgc ttgcagcaca tgttgcggat
    39421 cattggcaat cgctcgcagc aaagcctttg caggcccggt cggtgaacgt cgcccctgct
    39481 cccagttacg caacgtgtct acgcttacgg aaataagatc ggcaaattta gattgtgaca
    39541 accctgaagc gcggcgtatt tctttgattt tcatagcatc aacttcaaaa gtccgtgaag
    39601 gctgtcgcgt tccttcaata atttcattca tctgggccat gctgtgagtc aaccgctcaa
    39661 aaagtgcctt atccatttac cacctcgtat ttaacaaccg gagcattgct ttttcctggg
    39721 gagacagatc atctttaata cccttacgat aaataagcag taatctgatc tcataatgtt
    39781 taacctgatg aaagtaaata accctgacac cagcacgttt cccctttcct cctgagaccc
    39841 atcgaacctt tcttaaccca ccagtttcag gtattacctc accatagtca ggattcaagg
    39901 ccaggaaaaa ctgaaaacga ctgaattcat cgtcgttcag cagtttttga acatcttcag
    39961 taaaaatttc cgtttcgatg aagagcataa ttatacgcca ttggcttaga gcaacaatcc
    40021 tttttgtacg tcattgacgt accattgaaa ccactagctt actgatagtg ctccagcaaa
    40081 accacgtctc tgccgggttt gtctttacat ttgcgaggcg ctttccagat ttttcacgcc
    40141 cgtgaatttc cctgtatcca tccagcaaaa acgggtgtat aaaactgtac attcatacag
    40201 caaaatgagt tctactatgg cactggaaaa aggaattgca gagttagtcg aagagtttat
    40261 cgctgcgggt cgcccctcat cgcgccaaca aagtattacg cagcgcagag agggctatat
    40321 cgccagcgct gtccttgcgg gtgagacaga aacgcgggta gatattcaga ctatcgaact
    40381 tgaagggatg accttacgaa tagtgtcacc gctgaatgcc ccgacattac tcccgacgat
    40441 aatttattac tacggtggct gttttgttag cggcgggttc gcaactcacg acaaccagct
    40501 gcgccagtta gcctattacg ggcaatgtcg ggttattgcc gtccagtatc ggctggcacc
    40561 ggaacatact ttccccgccg cccatgatga tgcacaacga ggtgcagaat tagtccggca
    40621 acacgccgaa cgactcggcg ttgataaaca acgaataact cttgccggtg acagtgcggg
    40681 agggcatctg gcgctggtaa ctgctttgcg attgaagcgt gctggcgagt ggcaaccagc
    40741 acaactcatc ttaatttatc ctatgcttga tgcgactgcg catttcgaaa gctacatacg
    40801 caatggtcac gattacatca tcacacgcga cactttactg agcggctttg agatgtacct
    40861 gccaggcatt gaacgcaggc atcctgaagc cagccctatt tggcgcaatg atttcaatgg
    40921 cttgccacct gtacatatca ttaccgctga atacgaccca ctttgcgatg aaggtgaagc
    40981 gttgtatcac cgcatgacag ggcaaggagt gcaatgcacc tgccaacgct accttggcgt
    41041 tatccacgga ttttttcagt taggtggtat cagtgaggct gcgcgatcgg cgttacggga
    41101 tgttgcctgg agagcgggaa ggtaactccg gaccagggcc cagaaaaggt tttcagattg
    41161 aaaacctttt cagtcaagta aaacgcccct actcttcttc gttcccgccc tcttcatacg
    41221 ggccaaatgg cttcgcgggc agaacgatat acgtgccttc aaacactgca cccggcgtct
    41281 cgtcgccaaa gatttctact tgcatctgca cccgtgcttt tcgtccgcgc gccagacggt
    41341 cgagatcgcc acttaaggca ccaaggtcgg ctaccgcatg gggttttccg ctaatcggct
    41401 tgctgtagcg gatatgcgca tccgccagaa taatcgttcc gccgaggtgg cgttcgcgca
    41461 gcatcagcca gataagcccc caaccggtga gcgtagccag cgagaataaa ctcccggcaa
    41521 acagcgtgtg atgcggattc tgattgccgg tttccggcat ggtggtgata aatttttgcc
    41581 cggtatattg ctgaatgcgc acacccattt tttcgcttaa cgggatatgt tcataccacg
    41641 cttgctggag ctgggcgcac cagtcgccgc gatgaagaat atcatccaga gtggcgacgg
    41701 gtttaatcat cagaaaatgg cgaatcggcg tggtggttgg cgtggtgatt tcaccctgat
    41761 taacaaaccc cagcttggcg aaaaactcca ccgcgtcttc acgggcgcta caggtcacgc
    41821 gcttaacgcc ttcctgacgt gccaccgact ccagggtcat cgccatcagc gtgcctaacc
    41881 ctttgtcctg cacgtcggga tgaacggcca taaagcgaat ggacgcttca ttgtcggcat
    41941 taatatacag tcggcctacc gctaccagat taccctgctc gtcgacgacc atctggtgat
    42001 gcgccatcgc atcccacgcg tcgcgttccg aaccttttgg ttgatgcagg ggcttacgca
    42061 acatttccca gcgaaactga tagtaacgct ctaattcttc ttctgtttgt ggaacccgaa
    42121 ggtgatacat agcgatactc tctcttgttt cccgtgacaa ccctggaagc tggctcatac
    42181 ctgcaaccag aatgtcacgg ggccatcatt gaccagcgat acctgcatat ccgcagcgaa
    42241 gcgtcctgtt tgcgtgttca tatcttgctg acggcagcgt tcgacgaaat agtcatataa
    42301 cgcctctgcg cgatccggtg atgcgccttt ggagaaactt gggcgcatcc cccgttcggt
    42361 atctgcggca agggtaaact gggaaaccac cagtacactg ccgcccgcct gttgcacgtt
    42421 gagattcatc ttgccttcgg catcgctaaa gatgcggtag ccgagtacac gctcgcacag
    42481 acggtttgct ttctgttcgt cgtcatcctt ttcgacaccc aataacacca aaagtcccgc
    42541 gccaatttca cccgtcactt ctccctccac ggtgacgctg gcacgggtta cgcgttgaat
    42601 taatgcaatc atggttcgtc gtcttcttct tgttcagcag cttgttttaa tttgcggtat
    42661 tccccgagag tgacagtaat ttccgcgcca agcaagacga tacaccatgt ccagtagacc
    42721 caaacaaaga gaatggggat caccgccagc acgccgtaaa tgagctgata tgacgggaac
    42781 atggtgatat aaagcgcgaa acctttcttt cctgcttcga acaggagcgc ggcgacaaac
    42841 gcgccgacaa tcgcgtcgcg gttaggtacg cgaatggtag gaacgatgct gtacagcaac
    42901 caaaaggaga tccacgataa cagcagcgga aaaatacgca gcacgttgtc gatgacagta
    42961 ttgagatcgc tcgcccagcg cagggaaagc agataggagc tgatcgccag actggcccct
    43021 gccagcagcg gccccagcgt taaaatcatc cagtacacgg caaacgagta aattttgggt
    43081 cgcgctcgtt tactgcgcca gatggtattc aacgcgctat cgatggagta catcaacaat
    43141 aacgccgtga cgatcagccc gcacgccccg acggcggtca ttttgttgga attggcgaca
    43201 aactgttcga tatatcgctg gataacatcg ccagtagcag gcagaaagtt ggcaaaaata
    43261 aagtgacgca actgaatgct gacgtcggaa aacatgggaa aagcggcgaa aagcgcaaaa
    43321 acaacggcaa ccagcggcac taatgagagc aacgacacat aggcaaggtt acctgccagg
    43381 gttgtcatgt tgtcctcatc aatgcgttgc cagagtagtt ttagccaggc ccatagtgga
    43441 cgggtacgat gcctggcttt gtcctgaatg gtttttagca taacaccttc gcgaaatagt
    43501 ccgggatggt ggttttatct ttcaccagaa tactagtaat gcctagccga ttagctcctt
    43561 ctatattatc ggcgttatcg tcgaaaaaga ccgtatcgtc tggtgaaaaa ccttctgccc
    43621 gcaaaacatg ctgataaatt cgtgcttcag gtttgcgcat acccaagtct tgcgacagat
    43681 agatatggtc agcagcatca cggatttccg ggtattcctc cggccagaag gtagtatgca
    43741 ggcggttagt attggaaagc accaccacgc gatgcccctg ctcacgcagt ttatgcatga
    43801 tggcgatcac ttccggtcgt agcgcaacaa ataccgcctg ccaaccgtgg gagaactgct
    43861 catagcttag cggcagggcc atctcatgac acagtgcctc tgcgaacgct tcgtcgctaa
    43921 tttccccacg ctcatgctga tgaaacgcct cgcccatgtg gaaactcttc ttaagcgtag
    43981 ccagtggaac acgcgttaaa tcgctccagg cccccagcac acggttaaag tcgatatcga
    44041 caatcacatt acctaaatca aagatataga gcatttttgc ctcctttcgc gccacaagaa
    44101 attaactgta gcgggaaagg atgggtttgg ctatgtggca ataagggtaa tcttgtgatg
    44161 ctgattgcga aaaagcagag taatttcact ggctttttcg caatagatga atggttaaga
    44221 ttcaggtgta aattgccaac gagtttcgat gaccagcggc ttatctggtg tcacaaattc
    44281 cggcgttaga tttattgcgt taggtgcctg agtcagcggg ttaatacagg tggcatcggg
    44341 ctgtttatca aataccacca gactgtttgc agaagaggtc atggtcatcg cgagtttacc
    44401 aggccacagt aacttaacct tcaccccgtc ataaaaacca aaacagtcat cccagggacc
    44461 aacttgagga gagatacgat ttccagttgg cagttcatca ctacccgctt cttcttgcca
    44521 gtccgcatca aaaagcacct gcaacgattc tgtattttgc ggagtcagct ttttcgcaaa
    44581 ccacggatgc cagcctgcgg aggccgggaa tgtatcggca tatgaatgga cttccagttg
    44641 caaaaccagc gcatcgttct ccagcaaaaa agtctgaatc acttcccctt gccagggcca
    44701 cggtgaagtc aggggcatac gtaaagtcag ggaatctgct gttttgtcga tgatttccca
    44761 cgttgagtaa caagccatac catgcaacgc atgtggtggt ttattggcgg gtaaagaata
    44821 acattgccca ccagcattca gcgtcgcatt ccccagtcgc cctgcccacg gcaccattgg
    44881 gaaacagcca tactgaaaag ctctgcgctg cggctgccat tggcgtaata cttcagaacc
    44941 aaatgccttt aacgaggtta tcctggcacc atcatgcgga taaatctgca ggtgaatatt
    45001 gcctttttcc agcgtcacta actctcctac aggcccaggc catggcgcgt caaacgcctg
    45061 ttgtagcgcc aggtaatgct cgttttttcg ttcagttttc atgagattgt tccctgatgt
    45121 agcggtaaga agcggtttct tgttcatcgg ttggctcaat cagccagacg caaacaaagg
    45181 aaagaactga gacagcaaat aaaaacagag cgacatacca cggttttcct ccccctagcg
    45241 ccagcaaact tgaggcgata agggggctta gtccgccaag aatcgcggaa aattgataag
    45301 caaaagaaag gccggtatat cgtactttgg taccgaacat gcgggtgaaa agtgttggct
    45361 gcacggcaaa catcatcgtc ggacctaagt tgtagccaag gatcatactg caccagatga
    45421 tgagcgtact tttgctatcc agtaataaga agaaaggaaa cgcgaacagg acacaaaacc
    45481 ctgctcccga caaatacaga cttttttgac ctatacgatc tgataaccat ccaaccaatg
    45541 gacaactgaa aataccgatc gccgaggcaa tcaacatacc cgtcagggga atatctcgcg
    45601 acaatgctaa ttggctggaa atatagacaa taccaaaggc gttaataata ttagaggaga
    45661 cactttccgc cagcctcgca cccagtgcca ataaaatatt tcgtggatgt tttttgaata
    45721 attcaatcaa cggaggaacg gacttttctt tattattcgt cgttttttgc ttttgaaaat
    45781 ccagcgtttc ttcggtatgc aggcggataa acagcccaac gatcaacatc accgcagaaa
    45841 gccaaaacgg aatgcgccat ccccaggaga gaaactgctc cgaagtaaga aaatggttac
    45901 agagagcaaa aataccggtt gccagcataa tacccacaga cgcagccgtt tgcgggagtg
    45961 aacctaaaaa tccgcgtcgg gattcgggcg ctgattctat ggtcatcaat gccgctccgc
    46021 cgtactcgcc accaagacca aagccctgaa ttaaacgtag caccattaat atgagcggtg
    46081 cccagatccc aatttcctga tacgtcggaa taaaaccaat caaaaatgtg gagcaaccga
    46141 caatagccaa cgtccagata agcgttattt ttcgccctat tttatcgcca aaatgaccaa
    46201 agacgatgcc acctaaagga cgagtcagaa aaccgacacc aaaggtcgca aaggaagcta
    46261 taagacctat aaaaggatcg ctgtctggat aaaacagcgg tgcaaatacc agtcctgctg
    46321 ccgtgccaaa aataaagaag tcataccatt ccattaacgc gcctgcgaaa ctgcccataa
    46381 cgacacgtct catggcttta ccggaaagcc cttcacgcgg tgcgggtaac ttttcagaca
    46441 taattttcct ctcctggtag gcgagaaatc tgggatacga accactaaac gtgggcagtt
    46501 tgaattaatg cgcatcggct taaaccgatg cgcattaaat tatttcttca attcagccag
    46561 aacctctgcg tcctcagcat caacatttgc acccagtggt tcccaattaa tcaatacaca
    46621 ggtcaggaat cccaggaatg gcacgattgc caaccagtaa aacgcttcgg ttttcaacgc
    46681 accccacagc atcggccaga aaatgagtcc tgcaattgcc cctgtgcgca taatagcgcg
    46741 ggcaaatccg accccagtag ggcgaatagc gggaggataa gagagtgtgg caatggtcat
    46801 gcccagccca ccaggacccg ctgaatggaa gaaaataatt gatcccaata accctaaaga
    46861 cagccaggga ttagtcgttg ccagtgcgcc taacgacagc aatgctaagg tcacaacagc
    46921 aaatccatac atcgactgtc ggcgagtacc cagtcgttgg agaataaacg agccgatcat
    46981 cccgcctgtc accccacaaa gggcattcac gacggcagaa ccggtcaacg cgccagtaag
    47041 cccgccactt attattcccg ccaacgtaag aggaagataa acacctacgg cgttatattg
    47101 ccacgcctgc atggttgcca cgacacagcc aagaatggtg cgtttgcggt aacgatcatt
    47161 aaataagatg ccatatccac cactgtattt attctctgct ttttccgaga atttcgcttc
    47221 tgttgtaccc gatgccgcaa cgcgagcctg aacaccataa cgttttccca gaatgtcgca
    47281 cgcttcctgg taacgcccga cgcgtgcggc ccacattgcg gattcaccaa taaagaagta
    47341 acgcaaaatc atgaagatga ctgcaaaaat agctccgatg aatattccgt aacgccacaa
    47401 ttgttcttca gcgatacccg acagaagcag cggcaaaagc accaaataaa caacggttgt
    47461 cgaaacatac caggccattt gccagaggtt gaccgacgtt ccggttttct tcgacgttga
    47521 accacgaagc tctgccacgg cattggttgc caaagggaag tcgatgccta aaccaaagcc
    47581 catgatgacg cggcacacca gcacccacca gatactggga gcaatagcta ccgctgcagc
    47641 accgatggtg cacagcccca tgccaataat aaatgcccgc ttttgcccaa agcggtttat
    47701 tactcggttc gctaataaac cgccaattaa cgcggcgatt aatactgatg cattgacggt
    47761 tgcagcaaga cccggcgaaa tgccgaattg agcggcaatg tatttattac caaaccccac
    47821 catcgccgcc tggtaggcat caatcaatat gccgcccaaa gcaataaaaa taacgccgat
    47881 actggtgttg attgcagagt tcttattaac aatatcaatt acgtcctgtg gccgactaat
    47941 tgaataagtt gcaggactgg tgatttgact catcgcagtg tcctttttaa ttgttgtagg
    48001 gtggcgctga cgtgacgcag cgccagacag agatttagaa aatcattccg gcgcaaattg
    48061 cagcatgacc tttatggagt cattttgctg cgcgcgttcg aatgccgccg ctgcatcctc
    48121 aatggcaaat aaatcggtaa ccagttcact ggtatcaaac cgcccatccg ccagccattc
    48181 gataacagca tcgaaatctt cagggatgta catgccagag ttgagcaagt cacgctcgaa
    48241 acgttgcatc atcggtaatg gtatttcacg cggcccactt ggtacgccca tgcacacgac
    48301 ggtgcctccg gcatatacac gggtacatgc atcgttaagc gtggcctgcg ctgcaacgac
    48361 atcaatcgcc cccgtaaatc gcacatctgc ggccagctca cctggtgccc aaacttctgc
    48421 tgcgcccagt tttaacgcca gcgcgcgttt ggcagcgtca ggttcaatca cggtaatctt
    48481 acctgccccc ataatgcgca gtgcctgcac gatggataag cctatcgttc cggcaccaat
    48541 caccagtacg ctttccagag aagctttcgg cattcggtta acgcagtgac gagcacaagc
    48601 cgccggttcg gcaaaggcca acacttttag cggtaaagag gctggtgcga catggcaatt
    48661 acgcgcagga acaatgtgtt gtgagcgagc aaagcccggt gcgcgaaaac cagcaacctg
    48721 cggtggttca caaagattaa aacgtcctgc tttgcaggct cggcattcca tgcaagccat
    48781 gatgggatcg accacaacat gatcgcccgg ctgtacattt ttaacgtcgc tgcccacttc
    48841 cgtaacgcgc gctgcaattt catgaccggg gacgacaggc ggtttggcaa acggatgacc
    48901 gcctttcaga acatgcagat ccgaaccgca tatcccgtag aacacgggcg caatccgtac
    48961 ttcgtgcggt ttaagttgct ggtgtggtac ttcaacatat tgagtggtga ctttcccaat
    49021 atctgaaaat aaaacctggg taattttatc cattgttatt ctccagaatc gatatccata
    49081 ggggattagc gttgcgcgat accttcatcg acaatttcag ccagccgttg caagcgtgga
    49141 acggagacat cgcgcagcat ggtttgtgga tcttgtgcac caacaaccga cgcccaaacc
    49201 gctcgtccag ccaggaagcc cgacgcacca cctttcatgg caatacttac tgcacggcca
    49261 aaaatatcgg catcaacgcc agaagaaaga attacccacg gcatcttcat ctgatcgtta
    49321 agttgctgac aggcagcaag taaggttttt tcatcgcctt tgccccctaa tggcatctcg
    49381 gctttgtaaa gatcagcctc tgttccacca agctctgcgg cggcggcaac aatggcgctt
    49441 tcacgatcaa agtcccaacc gcgacgaggt ggacgcacca caggttcaat aatgctaacc
    49501 agcccggcac tacggcagcg acgaacaaat ttatcaacca ttgccagacg ttcctctgcg
    49561 ggttcatctt cacgccagag tacaagtaat ttcattgcct tagcccccat ttcacgggct
    49621 ttatgcgggt cgacggacat atctatttca acgctatcaa ccgggatgcc attacctggg
    49681 ataaaaagat cggcagcgac aatcaggccg caagaattag ccacagcgcc ctgctcgact
    49741 atttgttcaa gacaaaattg tttatccgcc agaacggcag aagcataagg agaaaggatt
    49801 cgggtcgcgg caactttaaa atcggtgagt acactgtcgg cgatgggttt tggctgccct
    49861 gctgccgcaa acatcaggcg catggcctca cgctgatcga cagctaacat ggcgaatcca
    49921 ccacctgggc gggagatatc tttcagcgta aatggggtga agtgggatga catagaaact
    49981 cctgttaata gataaaatta aagaccagcc tgctggcgaa cctgatttag cagggcgctc
    50041 cagtcctgcc gccctttgcc gtcttgactt gctgcggcgt aataactttc tgctgcaatc
    50101 cccatattga gcggcgcccc cgttttccga gcgacgtcaa ctgcaatacg cagatctttc
    50161 aatgccaggt ccaccatgaa ggcgggagaa agatcgcctt tcagcacttt gccaggccag
    50221 gtggtcgtaa aatgtccttt ccctgctgcc gtaccactca tcaccttaat tgcgacatca
    50281 agatttaatc ccagtgactc acataacaca gcggcttcgg aggacagcgc attaagcgca
    50341 atgctcatat agttgttaat tagcttcacg cggatcccca ttcctgggcc accagcctcg
    50401 accagctcat tacccatgca catgagaatc gggcgtgcac gcgcaatctg ctcatcagtg
    50461 ccgcccgcta aaatcagcaa tgtgccatca atcgcattca ctgacgttct gcccacgggg
    50521 gcgtccatca tattgatgcc tttttcttgt aattcccgta ttaatgcatc ggtctgtaag
    50581 ggatgaatag tcgacatatc aatcactaac gcgtcagatg aaacagtttc acagacgcct
    50641 ttttccccca acagcacctg tcgaacaatg tccccattgg gaagcatagt gatgataaat
    50701 tcagcgcttg ctgccgcttc cgctggggtt tgtgccgcag tggccccctg cgtaactagc
    50761 gcatcgacgg cctgtgtatt gacatcaaat acctgtaatg aatgcccttt ttgcaataga
    50821 ttgttagcca ttgggctacc catctgcccc agcccgagaa atgcaatggt tgccatgaat
    50881 actctcctgt ctgacattga caaaataatg acaattgaaa attcgttttc gtctgttttt
    50941 gagcatattt gtaatttatg ttcaaaaaca cgacacgcat cactaatttg atcatttgtg
    51001 tcatttaaat tgaccaaaga cgacaaaatt aaacaggaca agacaaatat gaccagaatt
    51061 gcatgcgtgg gtatcacagt tcaggacaga atttattctt tgcccactct gccggagggt
    51121 ggcgggaaat atcaggcaaa tcattatctt gagattggtg gcggcccggc agcaacagcc
    51181 gctgttgcaa tcgcaaagct tggcgtggag gttgatttca tcggtcgcgt cggcgatgac
    51241 agttgtggaa ataccttact tgcagaactt gagggttggg gcgtcaatac cgcattttgc
    51301 cgccgatatc ctaacgcccg ttcgtcgcaa tcagcgatcc tcgttgatca gcatggcgaa
    51361 cggattatcg ttaattatcc aagtcctgat ctcggtactg atgccgaatg gttagaagcg
    51421 atcgatttct ctcgttatga tctgattctg gccgatgttc gctggcatag cggtactgaa
    51481 aaagcattct cgctagcgcg ccttgcgggt gtgacaacgc ttttagacgc cgatatgaca
    51541 ccgcaggata tttctccact tgtcgcgctt gccgatcacg ccgtgttctc aacaccaggg
    51601 ctgaaacgca tgactggcct gcagtcacct gaagaaggtt tgttccaggc aacgacacaa
    51661 acagcaggta aagtgtatgt tacgctgggt tctgaaggat cgttgtggat tgaagatggt
    51721 catttgtgtc aacaggaggc attttctgtc aatgtggttg ataccactgg agcaggcgat
    51781 gtttttcacg gcgcactcgc ggtagcgttg gcagaaaaaa tgccaacaaa agaggctatt
    51841 cgttttgcca gtgcggttgc cgcgatgaaa tgtacccagc ctggcggtcg ggccggcatt
    51901 cctaatcgtg agcaaaccga atcatttttg tcactttatg cgtaaaatgg taaacatcta
    51961 ccgaggaggg gcaagggagt attcatgagt atcatcgaag tgacaggtaa tccacgccat
    52021 gaccaactcg ttcatctaat cgcagaacgc ggttatatga atattgaaga actggcacaa
    52081 ctgctggatg tttcaacgca aaccgtgcgc cgggatatcc gaaaactcag tgagcagggc
    52141 ttgatcaccc gtcatcatgg aggggccggg cgcgtctcca gcgtcatgaa taccgctttt
    52201 gagcaacggg aactttcgct caccgccgag aaacgggcga tcgctgaggc agtcgccgat
    52261 taccttcccg aacgctgtac cgtctttatc accatcggta caaccgtaga agccgttgcc
    52321 agggcattac tcaaccggcg tgatttacgc attatcacta atagcctgcg tgtggcacag
    52381 attctttata agaatcagga tattgaagtg atggtgccgg gaggcacttt acgcgctcat
    52441 aacggtggga ttatcggccc aggagccgtg gattttattg aaggcttccg cgcagattat
    52501 ttaatcacca gtataggtgc cattgaacat gacggcaccc tactggaatt tgatgtcaat
    52561 gaagcgttag tcgcgagaac gatgattaaa catgcgcgga atacattgtt agtggccgat
    52621 catacgaagt ttaccgcgtc tgctgccgtt tcaattggca atgcacggaa tgtcagggct
    52681 ttttttactg atgccccgcc tcccaattct ttctgccagt tgttaagtga agagaatgtt
    52741 gaactggtgg ttgccgagca agaagtatcc tgaaattgaa acttcggaaa atccgctggg
    52801 aatttcagcg gattttgttt tccataagcc aaaaaaaaac ctgccatcgc tggcaggttt
    52861 tttatgactg aaaaacgaaa ttaatcgtct ttcggtgcgc ggttagcgcg acgacgatcg
    52921 ttttccgtca ggtgacgttt acgaatacgg atagaggtcg gagtcacttc taccagttcg
    52981 tcatcatcga tgaactccag agcttgttcc agagtcatgc ggataggcgg aaccagaaca
    53041 acggcttcgt cagtaccgga agcacgcatg ttggtcagtt tcttaccggt caggcagttt
    53101 acagtcaggt cgttagagcg gctgtgaata ccgataatct gaccttcgta aacttctgca
    53161 ccgtgaccga ggaacagctt accgcggtcc tgcagaccga acagtgcgaa cgcgaccgct
    53221 ttaccctgac cgttagagat cagtacgccg ttctgacgct ggcccacttc acccggacgt
    53281 acgtcgtcgt agtggctgaa ggtggagtac agcagaccag taccggaagt catggtcatg
    53341 aactcagaac ggaagccaat cagaccgcgg cttgggatca cgtagtcgag acgtacacgg
    53401 cctttaccgt ctggattcat gtttttcagg tcgcctttac gttcgcccag cgcctgcatt
    53461 acagaaccct gatgctgttc ttcaacgtcc agagtcacgt tttcatacgg ctcttgttta
    53521 cgaccgtcga tttcacggaa gataactttc ggacgggata ccgccagttc gaaaccttca
    53581 cgacgcatgt tttcgatcag aacagacagg tgcagttcgc cacgaccaga aacgcggaac
    53641 gcatcggcgt cttcggtttc ttctacgcgc agcgcaacgt tgtgtaccag ttctttgttc
    53701 agacgatcca ggatctgacg agacgttacg aacttacctt ctttaccgca gaacggcgag
    53761 gtgttaacgc agaagaacat agaaacggtc ggctcatcaa cggagagtgc cggcagcgct
    53821 tcaacgtttt gcgtgtcgca aacggtgtca gaaatgttca gttcgcccag gcccgtgatc
    53881 gccacgatat cgccagcttc cgccagatcg gtttcgatac gttccagacc gaggtggccc
    53941 agcactttac cgactttcgc gttgcgggtt ttgccttcgc tatcgatgat agtaacctgt
    54001 tggttcggct tcactttacc gcgcttgatg cggccaatgc cgataacgcc aacatagctg
    54061 ttgtaatcga gctgagaaat ctgcatctgg aacggaccgt caaggtcaac gtccggcgca
    54121 ggaacgtggt caacaatcgc ctggtacagc ggggtcatgt cttccgccat atcttcgtgg
    54181 tccagacccg cgataccgtt cagcgcagaa gcgtaaacga tcgggaagtc cagctgctcg
    54241 tcggtcgcgt cgaggttaac gaacagatcg aatacctgat ccacaaccca atcaggacgc
    54301 gcgccagggc ggtcaacttt gttgataaca acaatcggct tcaggccgta agcaaacgct
    54361 tttttggtta cgaagcgcgt ttgcggcatc gggccgtcaa atgcgtcaac caccagcagc
    54421 actgagtcta ccatggacat tacacgttca acttcaccac cgaagtcggc gtgccccggg
    54481 gtatcaacga tgttgatacg gtaatcattc catttgatag cggtgttttt cgcgaggatg
    54541 gtaatcccac gctctttctc caaatcgttg gagtccatca cgcgctcttg ggtttcggca
    54601 cgagagtcga acgtaccgga ttgttggagc agcttgtcta ccagggtggt tttaccatgg
    54661 tctacgtgcg cgatgatggc gatattacgc aatttttcga tcacaacttt gcctcaggca
    54721 ttagaaatag cgcgttattg tacacggatt aatcgcacta caaaacagga tcacaaacat
    54781 cctccgcaaa caagtattgc agagtccctt tgtgatcgct ttcacggagc ataaaaaggg
    54841 ttatccaaag gtcattgcac caatatggtg cttaatgttc ccattgaagc actatattgg
    54901 tgcaacattc acatcatggt gcagcccttt tgcacgatgt taagcatgat aacgcctttt
    54961 aggggcaatt taaaagttgg cacagttttc gctttatctt ttttacggcg acacggccca
    55021 tttaattgca gatttcgtta ccacgacgac aatgaccaat ccaggagagt taaagtatgt
    55081 ccgctgaaca cgtactgacg atgctgaacg agcacgaagt gaagtttgtt gacttgcgct
    55141 tcaccgatac caaaggtaaa gaacagcacg tcactatccc tgctcatcag gtgaatgccg
    55201 aattcttcga agaaggcaaa atgtttgacg gctcctcgat tggcggctgg aaaggcatta
    55261 acgaatccga catggtgctg atgccagacg catccaccgc agtgattgac ccgttcttcg
    55321 ccgattctac cctgattatc cgttgcgaca tccttgaacc tggcaccctg caaggctatg
    55381 accgtgaccc gcgctctatt gcgaagcgcg ctgaagatta cctgcgttct actggcattg
    55441 ccgacaccgt actgttcggg ccagaacctg aattcttcct gttcgatgac atccgtttcg
    55501 gatcgtctat ctccggttcc cacgttgcta tcgatgatat cgaaggtgca tggaactcct
    55561 ccacccaata tgaaggtggt aacaaaggtc accgtccggc agtgaaaggc ggttacttcc
    55621 cggttccgcc ggtagactca gctcaggata tccgttctga aatgtgcctg gtgatggaac
    55681 agatgggtct ggtggttgaa gctcatcacc acgaagtcgc taccgcaggt cagaacgaag
    55741 tggctacccg cttcaatacc atgaccaaaa aagctgacga aattcagatc tacaaatatg
    55801 tcgtgcacaa cgtggcgcac cgtttcggta agaccgcgac ctttatgcca aaaccgatgt
    55861 tcggtgataa cggttccggt atgcactgcc acatgtcgct gtctaaaaac ggcgtcaacc
    55921 tgtttgctgg cgacaaatac gcaggtctgt ctgaacaggc gctgtactac attggcggcg
    55981 taatcaaaca cgctaaagcg attaacgccc tggcaaaccc gaccaccaac tcttacaagc
    56041 gtctggtccc gggctacgaa gcaccggtaa tgctggctta ctctgcgcgt aaccgttctg
    56101 cgtctatccg tattccggtg gtttcttctc cgaaagcacg tcgtatcgaa gtacgtttcc
    56161 cggacccggc ggctaacccg tacctgtgct ttgctgccct gctgatggcc ggtcttgatg
    56221 gcatcaagaa caagatccat ccgggcgaag ccatggacaa aaacctgtat gacctgccgc
    56281 cagaagaagc gaaagagatc ccacaggttg caggctctct ggaagaagca ctgaacgaac
    56341 tggatctgga tcgcgagttc ctgaaagccg gtggcgtgtt cacggatgaa gcgatcgatg
    56401 cgtacatcgc tctgcgtcgc gaagaagatg accgcgtgcg tatgactccg catccggtag
    56461 agtttgagct gtactacagc gtctaatagt tgaagttgta ctacccggcg caacaacgcc
    56521 gggatttagt tgccgtggaa actttcagcc catctctgca tgggcttttt tctccgtcaa
    56581 ttctctgatg cttcgcgctt tttatccgta aaaagctata atgcactaaa atggtgcaac
    56641 ctgttcagga gactgcttta tggcaacagg cacgcagccc gatgctgggc agatccttaa
    56701 ctcgctgatt aacagtattt tgttaatcga tgacaacctg gcgatccatt acgccaaccc
    56761 cgccgcgcaa caactgctcg cccaaagctc ccgcaaattg tttggtacac cgttaccgga
    56821 actgttgagc tacttctcat taaatatcga gctgatgcaa gaaagtctgg aggcggggca
    56881 aggttttacc gataacgaag tgacgctggt catcgacggg cgctcgcata tcctttctgt
    56941 gacggctcag cgtatgccgg acggcatgat cctgctggag atggcaccga tggataacca
    57001 gcgccgctta agtcaggaac agctacagca cgcccagcag gttgctgccc gtgatttagt
    57061 gcgcggcctg gcacatgaga ttaaaaatcc gcttggcggt ttacgtggcg cggcgcagct
    57121 gctcagcaaa gcattacctg atccgtcact actcgaatat accaaagtga ttatcgaaca
    57181 ggcggaccgg ctgcgaaatc tggtcgaccg tctgttgggg ccgcagctgc ccggtacgcg
    57241 cattaccgaa agtattcaca aagtggctga acgcgtggtg acgctggtgt cgatggaact
    57301 gccgaacaac gtgcggttga ttcgggatta cgaccccagc ctgccggaac tggcgcacga
    57361 cccggatcaa attgaacagg tcttgctgaa tattgtgcgc aatgcgctac aggcgctggg
    57421 gccggagggt ggtgaaatca ttctacgtac ccgcacagcg tttcaactga ccttacacgg
    57481 cgagcgctat cggctggcgg cgcggattga tgtggaagat aacgggccgg gcattccgcc
    57541 tcatttgcag gatacgctgt tttacccgat ggtcagcggc cgcgaaggtg gcaccgggct
    57601 tggcttatcc atcgcccgta atttgattga tcagcattca ggcaaaattg aatttaccag
    57661 ttggccaggt cataccgagt tctcggttta cctgcctatc aggaaataaa ggtgacgttt
    57721 atgcaacgag ggatagtctg ggtagtcgat gacgatagtt ccatccgttg ggtgcttgaa
    57781 cgtgcgctcg ctggagcggg tttaacctgt acgacatttg agaacggcgc ggaagtactg
    57841 gaggcgctgg cgagcaaaac gccggatgtg ctgctttcag atatccgtat gccgggaatg
    57901 gacgggctgg cgctgctcaa gcagattaaa cagcgccatc cgatgcttcc ggtcatcatt
    57961 atgaccgcac attccgatct ggatgctgcc gtcagcgcct atcaacaagg ggcatttgat
    58021 tatctgccca aaccgtttga tatcgacgaa gccgtggcgc tggttgagcg cgccatcagt
    58081 cattaccagg aacagcagca gccgcgtaat gttcagctta acggcccaac gaccgatatc
    58141 atcggtgaag cgccagccat gcaggacgtg ttccggatta tcggtcggct ttcgcgttct
    58201 tctattagcg tgctgattaa cggcgaatcc ggcaccggta aagaactggt cgctcatgcc
    58261 ctgcatcgcc acagtccgcg agccaaagcg ccgtttatcg cgctcaatat ggcggctatc
    58321 ccgaaggatt tgatcgaatc cgaactgttt ggtcacgaga aaggcgcatt taccggcgcg
    58381 aataccattc gtcaggggcg ttttgaacag gctgatggcg gcacgttatt tctcgatgaa
    58441 attggcgata tgccgctaga tgtgcagacg cgtttgctgc gcgtgctggc agacggtcag
    58501 ttttatcgcg ttggcggcta tgcgccggtg aaagtagatg tgcggattat cgctgccact
    58561 caccagaatc ttgaacagcg ggtgcaggaa ggcaagttcc gtgaggatct gttccaccgc
    58621 ctgaacgtca tccgcgttca tctgccgccg ctgcgcgaac gtcgggaaga tattccccgt
    58681 ctggcgcgcc attttttaca ggttgccgcg cgagagctgg gcgtagaagc gaagttgctg
    58741 catccggaaa ccgaagccgc gctgacgcgt ctggcgtggc caggcaacgt gcgccagctg
    58801 gaaaacacct gtcgctggct aacggtgatg gctgccgggc aggaagtgtt gattcaggat
    58861 ttgcctggcg aactgtttga atcaaacgta ccggaaagca cttcacacat gcagccggac
    58921 agttgggcaa cgctgttagc acagtgggca gacagagcgc tgcgttccgg tcatcaaaac
    58981 ctgctttccg aagcacagcc agagctggaa cggacgttac tgaccaccgc gctgcgacat
    59041 acgcaggggc ataaacagga agcggcgcgg ctacttggct ggggtcgcaa caccctgacg
    59101 cgtaagttaa aagagctggg gatggagtga ttcacggctt gtgtgtaaag attgattatt
    59161 gagcgcaaat tgctggtatt ttgcgcttta ctgttccgat aagttcagta tgatcttgcc
    59221 cggaaaacgg ggagagtcat tatgctggaa tcaataatta atctggtatc gagtggcgca
    59281 gttgacagcc acacaccgca aactgctgtt gctgccgtgc tgtgtgccgc gatgataggg
    59341 ctgtttagct gaagctcgtt gtttacgccg gatgcggaga aagtcgtagg cctgataaga
    59401 cgcaaccagc gtcgcatcag gcgttgattg ccggatgcgg cgtaaacgcc ttatccggcc
    59461 tacaaaagca ataatttcaa cagattttgc aggcctgata agcgtagcgc atcaggcaat
    59521 cttgttctca gcacattgat ggcgctttcg ttttctactt tgtaaacgaa gcgccattca
    59581 caatttaaat cacccgagag aactgctgca tccgcgcttt ctggcgcaga taggtatcaa
    59641 agcacatgca aatgttgcgg atcagcaagc gacctttcgc cgtcacctgt attcccttct
    59701 catccacatc caccagccca tcttttgcta acggggcgag cagcttgaga tcttccgcaa
    59761 agtaatcagc gaagagcaaa tcccactgtt gctcaatagg ggcgtaatcc agacggaagt
    59821 tgcagatgag cgacttaatc acatcgcggc gaatacagtc atcacgcgtt agcgcaatac
    59881 cacgccacag cgcattgcct tgttcatcca cttgctgata gtactgcttc aactctttct
    59941 ggttctgcgc gtagcagtcg ccaatcatgc tgatggcgga aacgcccatc cccagcagat
    60001 cggtatcgcc ctgagtggtg tagccctgga agttacgatg cagcacgcct tcacgctggg
    60061 ccaccgccag ctcgtcatcc ggacgggcaa agtgatccat accgataaac tgatagcccg
    60121 attgtgtcag gaaggcgatg gtttcctgca ggatatcgag tttttgctgc ggactcggca
    60181 ggtcagcatc tttgattttg cgctgggcgg caaaaatggt cggcaaatgc gcgtagttaa
    60241 agacgctcag acggtcaggg ttcagttccg ccacacgctt cagggtaaag gcgaaactct
    60301 ccggcgtctg tttcggcagg ccgtaaatca ggtcaatgtt ggtggaggta aagccaatct
    60361 cacgcgcatg gttaagcagt gcaaagatga actcttcatc ctgctcgcgg ttaaccagac
    60421 gttgcacttc tttgttgaag tcctgcacgc ccatgctcag ccgattaaag ccttcggcgc
    60481 gtaaatgatc gagtacatcc agttcgattt cccgcggatc gacttcgatc gagatctccg
    60541 catcggcatt gaactggaag ttttcgcgca gcagcttcat cagacggctg atttgcgctt
    60601 tattcagata cgtcggcgtt ccgccgcccc agtgcaattg gctgacgtga cgcccggcga
    60661 acagcggtgc acgatggacg atttcttgct ccagcgcgtc cagatactga tcggccttgt
    60721 gctgctggcg agtaacaatc ttattgcaac cgcagaagta acaaagctta tggcagaacg
    60781 gaatatgtac atagagagat aatggacgct caggatagcg cgccacagct tgtaaaaacg
    60841 cctgttcgcc gaagtcttct gaaaactcca gcgcggtcgg gtacgaggtg tatcgtggcc
    60901 cggaatagtt atatttctgg atcagggcca gatcccagtc gatttgctgt acagacatgc
    60961 tcactccttc cgatggcgtc tctggcggct acggcgtacc ggcggatgcc cgtttcgagt
    61021 catcagccgg ttgcgcagcc acttttgtcg ccgcgacaac cgctgtagtt taacgaataa
    61081 ccacaccaga taacatataa ccggaagggt tatcagcaga acgggaaggc ccacggcggc
    61141 aatccgttag ttgccccgca gcagacgcat catgtcttct tgcttctcgt cttcttcctc
    61201 ttcttcgtca tcgtcataag agaggccgag tttctgcatc aactcatcaa tacgatccag
    61261 tttggcatcc acccaggatt gctcttcggc gctcagggtt tcgcctgctt ccagacgttc
    61321 cagcagcgca tccagacgct catccgtttc cagtaactcc aactccgcct gcggtgaaag
    61381 cataggtttc tcactcttcg gtttgtgctg tttggtgact ttttcagtca cgcccaatgg
    61441 aataggggtt ttactgccaa tacgtggatc ttttggtgcg ttctgacctt tgctgcctga
    61501 cgtggtgtta ccgcccgctg cgcggctgcc cggcgcatga ccacgacgtt ttttctgacg
    61561 cttacggtca cgagcttcct gatccagctc ctcgcgtgtt tttcgacgcg cttttgcatg
    61621 acctttgctg cgtgagtttg aagatgatgg tttcataatg gttcgtcttt tagccgtttt
    61681 attcagtata gatttgcggc ggaatctaac agaaagcaag caaagaaaaa aggcgacaga
    61741 ttactctgtc gccttttttc ctgactcata acccttaacg ggtcttacaa tccttgcagg
    61801 ccgccaacac accctgtttt tccattagcc ggaacaatcc gtgttgattc catttccatt
    61861 taattacgtc tccggacgtt tatcttcctg acaatcctct gtcttcgcct cctggcgctc
    61921 ctgaccctca tcctgagtca ttgttcctgt tagcgtcctc gctctatggg tgctacttta
    61981 cgcctttgct ttaaataaac aatcaaccgc catcagtatt tgcacatttt cagagtttta
    62041 tataaaagca attcactgat ttatatagct tatttgacat acgtcgcaga attttctctg
    62101 ctatttcgca taaagactat cggcaatgtc tcacaaagca tatggctttt acttacaacg
    62161 ctcacgccga aaaatccgcc ttttattatg gttcaggtat aatcgccgca aagctttgac
    62221 tgatggagac gaccgctttg actaatttga attatcaaca gacgcatttt gtgatgagtg
    62281 cgcctgatat tcgccaccta ccttccgata ccggaattga agtggctttt gcaggccgtt
    62341 ccaacgcagg taaatccagc gcgctgaaca cgctgactaa ccagaaaagc ctggctcgta
    62401 cctcaaaaac cccagggcgc acccagctta tcaacctgtt tgaagtggct gacggcaagc
    62461 gtctggttga cttgcctggg tacggttatg cggaagtccc ggaagagatg aagcgcaaat
    62521 ggcagcgcgc gctcggcgag tacctcgaaa aacgtcagag cctgcaaggt ctggtggtgc
    62581 taatggatat tcgccatccg ctgaaagatt tggatcagca gatgattgag tgggcggtag
    62641 acagcaatat cgccgtgctg gtactgctga ccaaagcgga caaactggca agcggcgcac
    62701 gtaaagcgca attgaatatg gtgcgtgaag cggtgctggc gtttaacggt gatgtgcagg
    62761 ttgaaacgtt ttcttcgctg aagaaacaag gcgtggacaa gctgcggcag aaactggata
    62821 cctggtttag cgagatgcag cctgtagaag aaacgcagga cggcgaataa ttttcttgcc
    62881 ttaatgcttg tgccggatgt ggcgtatccg gcccgtaaat tcaatagatt acaattctac
    62941 cgttggcctg ataaacaggg cgcatcaggc attacggatc ttttctttcg cccaataaaa
    63001 aacgccccag tcattactga ctggggcggc taaaatattc agccaaatcc gattacgtga
    63061 agtaaaaggt ctgaaagata gaacatctta cctctgtacc ctacgcgact aactttactc
    63121 ttttttgttc agttcagaaa gcattttttg taattttttt tcagttgttg cataggaatt
    63181 tctaatagcc atcacaaaac gtgacagctt atgttgctta cttacgaaaa aagggcatgt
    63241 tcaggcgaat cttagtgcgc ctgatcccag ttttcgccac tccccacttc caccagcaac
    63301 ggcacatcca gacgggtaca gttttccatc agttgatgaa tctgcttcgc gacggcatcg
    63361 acatcatctt tatggacttc aaataccagt tcatcgtgta cctgcatgat catacgcaca
    63421 cgcggttgct cagcctgtag ccacgcatca acggcaatca tcgcccgttt gataatgtcg
    63481 gcggcggttc cctgcattgg cgcgttaatg gctgcacgtt cagccgctgc acgacgagcc
    63541 ccattgctgg atttgatatc cggcagatac agacggcgtc cgtccagcgt ttcaacgtag
    63601 ccctgctctt tcgcctgagc acgggtgcgt tccatatact ccagcacgcc agggtagcgt
    63661 tcgaagtaaa ggtccatgta cttctgcgct tctttacgtg gaatgttcaa ttgccgcgcc
    63721 agaccgaaag cactcatgcc ataaatcaga ccaaagttga tcgctttcgc gctacgacgt
    63781 tgctcgctgg tgacggtttc cagtggcaaa ccaaacactt ctgccgccgt tgcacggtgg
    63841 atatcttttc cttccgcgaa tgcggtcagc aagcctttgt cacgcgagag atgcgccata
    63901 atgcgcagtt caatctgcga gtagtccgct gagacaatca cataatcctc tggcgcaata
    63961 aacgcctggc ggatacggcg accttcttcg ttacgcaccg gaatgttttg caggttagga
    64021 tcggttgacg ataaacgtcc cgttgcggtt actgcctggt gataagaggt atgtacacgc
    64081 ccggttttcg ggttgatcat caacggcagc ttgtcggtgt aggtcgattt cagcttcgcc
    64141 agaccacgat attccagaat cacttttggc aacggatagt ccagcgccag ttcttccagt
    64201 acctcttccg acgttgacgg cgcgccaccc ggagttttct tcagcggttt aatgccctgt
    64261 ttttcaaaca gaatggtttg taactgcttg gtggaagaaa ggttaaattc ttcacctgca
    64321 atttcatgcg ctttcttttc cagctcagcc agacgcaagg tgagctcttc agagtgattg
    64381 tgcagcactt tcggatcgat cttcacaccg ttacgttcaa tgcgtgaaag caccggcacc
    64441 agcggcattt cgatattctc gaagacgttc aacggccctt tgtgtttttg cagatccggc
    64501 cacattttca gatgcaactg caaggtgaca tctgcatctt cggcggcgta acgtccggct
    64561 tcttcgaggg caatctggtt aaaggtcagt tgattttttc ctttaccagc aatctcttca
    64621 aaagtgatgg ttttgtgctt caaccaacgt tccgcgaggc tgtccatatc gtgacgcccg
    64681 gcaacgctat tgagaatgta ggactccagc atggtatcaa acgcaatccc acgcagctca
    64741 atgccgtaat tcgccagaat accgcgatcg tatttcaggt tttgcccgac cttcagcgcc
    64801 ttttcatctt ccagcagcgg ttttagcaac tcgagtgcac gctcgcgaga gatttgatcg
    64861 ggcgcatcaa gataatcatg agcaaccgga atatatgccg ctacgcctgg ctcgatagca
    64921 aaagaaagcc cgaccaggtt agcagagatg ttatcaaggc tgtcggtttc ggtatcaaat
    64981 gcaaataccg gcgctttttc cagcttcgca atccacgctt tcagtgtttc ttcatcaagg
    65041 atggtgacgt agttgtcata agaaatcacc gttgccgtca cttctggcgc ttcgtctgca
    65101 acactggttt cctgcggcct ggctgcgggt ttcgcccctt tagcctgtag ccatttgccc
    65161 gcttcgacat cagcagtcca gcgtttgaac tcatactttt tgaacagccc taacaactct
    65221 tccgccgccg gtggctgcac ttccagttgt tcacaggtca gctccagttc aacgtcggtt
    65281 ttaatcgtcg ccagctggta tgagagataa gcaacttctt tgttttgctc gagcttggct
    65341 gccattgttt tcgcgccacg gaagctcaac ccagcaattt tttctggctc ggcatacagc
    65401 gtatccagcc cgccaagacc ttgcagcaat gcctgcgcgg ttttttcacc gacgcccggt
    65461 acgccaggga tgttatcgga ggagtcaccc atcagcgcca ggaaatcgat gatcagttct
    65521 ggcggcacgc cgtacttatt caccacctct tccggtccga ggatggtatt cgtcatggtg
    65581 ttgataagcg taatatttgg cgtcaccagc tgcgccatat ctttatcgcc agtgctgatc
    65641 agcaccggac gcccggcttt ttcggcttcg cgcgccagag taccgataac gtcgtccgct
    65701 tctacgccag aaaccgccag cagcggcagt cccatcgctt taaccatcgc gtgcagaggt
    65761 tcgatttgtg ctcgcagatc gtccggcatt ggcgggcgat gtgatttgta atgttcaaac
    65821 agttcatcac gaaaggtttt tcccttggcg tcaaagacca ccgctgcatg cgtcggttta
    65881 tattgcatga tcagactgcg cagcatgttg aggacaccat acatcgcacc ggtcggctcg
    65941 cctgcgctgt tagtcagcgg gggaaacgcg tgatatgcgc gataaagata agatgaacca
    66001 tctacaagga taagtggatt ttgggggatc tgaaccataa tgtccgtgcc tgtttatcag
    66061 attatgggta aaggatgcca cagacaggat gaaaacatga gtttttcacc gcttttcgtg
    66121 aaaatctttt gtagatcttc tggatcgctc gcaaatcgtc atgtggataa ctttgtgcat
    66181 aaattattta catcgctttt aatttattat catgcttttt acagcatgat gtttgtcttt
    66241 gattttcatg cagttaaaaa taaagccatc ccttgagata atgggatttt ttctaatgtg
    66301 gatagatatg aattattttt ctccttaagg atcatccgtt atttgggtcg ttttctgcta
    66361 aaatctgcgc cttgcgcttc tttagcgcac tgtctatggc taaccttttg aataaattca
    66421 ttatgacgag aatactcgct gcgataaccc ttttgctgag tatcgtattg accattttgg
    66481 tcactatttt ttgctccgtc ccgatcatca ttgccgggat tgtaaaacta ttgcttcctg
    66541 tgccagtcat ttggcgaaag gtttcgcgtt tttgtgattt tatgatgtat tgctggtgtg
    66601 aaggtctggc ggtattactg catctgaacc cacacctgca atgggaagtt cgcgggctgg
    66661 aagggttaag taagaaaaac tggtatctgc ttatttgtaa ccaccgtagt tgggcagata
    66721 ttgtcgtact gtgcgtgctg tttcgtaagc acattccgat gaataaatat ttcctcaagc
    66781 agcagctggc ctgggtgcct tttcttggcc tggcatgctg ggcgctggat atgccgttta
    66841 tgaagcgtta ttcccgcgct tatttattac gtcatccgga gagacgtggt aaagatgttg
    66901 aaaccactcg gcgttcttgt gaaaagtttc gcctgcatcc caccaccatt gttaatttcg
    66961 ttgaaggctc ccgtttcacg caagaaaaac atcagcaaac gcactccact tttcaaaact
    67021 tgttgccacc aaaggcggca ggcattgcga tggcgctaaa tgtactgggt aaacaattcg
    67081 ataaactgct taatgttacg ctgtgttatc cggacaataa ccgtcagccg ttcttcgata
    67141 tgttaagcgg taaactgacg cgaattgtcg tacatgtgga tttgcagcct attgccgatg
    67201 agttacatgg cgactacatc aatgacaaaa gctttaagcg ccattttcag caatggctga
    67261 actcactgtg gcaggaaaaa gaccggcttc tgacgtcgtt gatgtcatca cagcggcagg
    67321 acaagtaaat tttgctcgcc tctgaatgag cagaggcgag tgagtatttt aatgaacaaa
    67381 acgtccggca cgagacataa attcttcttc gctcatctcc tgtccgttaa aaacaacttt
    67441 acccggtgta taacgcagtt gcagcgaggc ggtattgttg tcaatcgtga ttaactgcaa
    67501 catctgacct aaggtcatca tcccgctgat ttgtttatca gactgctttt gcgctttttc
    67561 cgcatccatt ccttcagata aattaagctg ttttgcggtt tctgtggcga cattaagcgg
    67621 taatttcaca tcaaaattga gcgatttaat atctttgttt gtggatgatg aagatttggc
    67681 tgggtcggca atactgatat ccagattggc atttagttcg ccgagtgcat tcttccatct
    67741 taccggttgt ttaatggtcg gctcactttt ttgtaataac ggtaaatact ctttgaacaa
    67801 tgcagtattc acttcttgca gagcaacttc atcgtttgct aactcagggt gtgcagcaag
    67861 ctgcttctgc atcgcaatgt tatactggat gataaattgg cgcaccgctg agggatcaat
    67921 agattcagca atcaatgacc actcaccact accgagttgc tgattccctt ttgttaactt
    67981 atcaagttcg taggtcagat tgacattgat ataatctttg tctttaacgc gatccagctt
    68041 ggtttttgca acgaaagcat cgatttgggc aacgtcttcc ccgtgattga taatgttaat
    68101 ctgattaaat ttcgactcgc tttcaccaac cggaaatttc ttttcttcta atcgcgccag
    68161 agaatcaatg gtaaaacttt tcgccgttac tttgttcatt ggtgataatt gcagaacaat
    68221 atcttcaact ttgccttcaa tatccaggtt agacaatgaa ctatcatcac cattaaaagt
    68281 aaactggcct tcaccaaaag aaaactttcc atactctgca ggggcaacat ctaatgtcgt
    68341 ggagaatgag ccaccaaacg cgaatcgcaa tgtcgcttcc acgggcgatt tatttttcgc
    68401 ggcgataaat agcggttgtg tcagctcatt attcactaag ttcacttttg ccgctgccag
    68461 tgctgggatg acattaccat gcattaacat tgtgatgggc aacggaccgt gctcaacatc
    68521 cacatcaaat acaactttct ggcctggctt gatattgaga tcgggtgcac cgttatcaaa
    68581 tgtcatttgc atttgaaaac gggaattaaa aaaacctttg tcaaaatttt tataacttaa
    68641 cgtcatgtcg taggcatgtt cacctttcta tttagcatcg ttaaaatctt taataaactt
    68701 ttcgacacct ggctgaattt gcgtacctgt gtaccatgtg ccaccacccc agattacgga
    68761 taacgcaaca atggcacctg tagctgactt acgtatcata taaatattcc ctgataaaac
    68821 agcaaaactt tgaatatcca cttatgctga aataatgtcc agcagcagga cgcattatca
    68881 gaatgtattt atatttatta aataataaaa aagcccatga atattcacgg gctttatgtt
    68941 atttacattg aattattttt tctcggacag atatttcaca gtatcagcat actgctgaac
    69001 aaaaacatcc atattactgg tatccatacc ctgcggattc agctgatatt taccgttaac
    69061 aaacatcgcc ggaacaccac gcaattgcac gtcagctgcg gctttttcct gctgagcgac
    69121 cagagatttc accacgaagc tgttccacgc cgcgtcgtac tcttcacctt taatacctgc
    69181 gttgataaat acatcgcgga tatcagatgc tgaacgaatg gtctgggttt tttgtacgcc
    69241 ttcaaacagc ggaactgtga ctttgtcttc cacgcccagc gccatcgcca cagcccatgc
    69301 ctgagtcagc tctttgccca ggtcaccccc catgaagttg acgtggtatt tagtcatctt
    69361 cacgccttcc ggcagttttt tcttcacgtt atcagaaata tgcagaactt cttcaaactg
    69421 atagcagtgc gggcagaaga aagagaaaaa ctccagcact tgcggcgcgc cagcaactgg
    69481 tttttccagg gtagtgtact gtttaccatc ttcatactgc gccgccgatg cgctaaacgc
    69541 taaaactaaa ccagccagcg ccagccaaat ctttttcatg atctactctc tccgattaat
    69601 acataggtgt taattgcaaa gggggttctt gtagaacttt tgcctgttct ataaaagtcg
    69661 ccgtctgtcg tagccagtaa tcttccccgg ttaaccacgg gaaatttttc gggaacgcgg
    69721 gatcagccca acgccgcatt agccaggcaa gataataaac caaacgcatg gcgcgtaaag
    69781 gttcaatcag tccgatttca gcggtgtcga actcgctaaa ttcttcataa gcctcaataa
    69841 tagtttccag ttgcatccgc tgctcggctt tatcgccatt gagcaacatc cacaaatcct
    69901 gaacggctgg accattacgt gcatcatcca gatcaacaaa cattgggcca tcgcgccaga
    69961 gaatattccc ggcgtggcag tctccatgta gccgcagaac ggtgaaatct tcccgccagt
    70021 gtgctgtaac ggcggcaatc agctcatctg tcgctttcag gaatgccgct ttcaacccgg
    70081 aaggtatcag tgtagcgtcc tcaaacagct tgcgtggctc aatgagatat tcattcaaac
    70141 cgatggtcgg gcgatggata aaaagctgtt tgcgccccgt ctggtgcata cgccctaaat
    70201 aacgcccaac cgcttccatc tgatcgatat tatcagcttc gaactggcga ccaccgacgc
    70261 ttggaaaaac agcgaaataa aatccctgat ggttcaataa agtctgacca ttaaaggcca
    70321 caggtgctgc gaccggaact tcatcgttaa ccagctgcaa cgcaaattga tgttcttcga
    70381 ggatttgatc ggctgtccaa cgttcagggc gataaaattt gacgacaaaa cgtcgacgat
    70441 cttcgtcctg aaattgatag acacggtttt catagctgtt aagcggggta agaccggaat
    70501 ccacccggat cccatgctca aacagagcgt ccatgatggt atccgggtgt agtgtctgga
    70561 aagtaaaagc gctgttgttc atcccatcat ccggaaaaca ttacgaatga tgaaggatat
    70621 catttcacga tgattttggt tgcgccgctt acaagctttt actctttaat tacgccacgt
    70681 gcgcgtaata gcgccgtttt gaaatcttct tcataatctt tctgcaaacc cgggatcacc
    70741 gcatctttcg cggaatcacg cattttcagg tgatagatca gaatgtcatc cgtcaaatcc
    70801 gccagttcgc cgtcaaaacc tgactctttc gccagtttct gcaaaaattg cagcaggtta
    70861 aggtctggct ctttttgcca ggctggctgg aggagttcaa taacttcatt cagacgttta
    70921 catttcatag taatgctcct tactcttgag acagacacgt tagcagggtc aatcccacaa
    70981 taaaagaggc gatatcggtg aatctgatga cgacgataac aggcgttgtg ctggcgggcg
    71041 gtaaagccag acgaatgggc ggcgtagata aaggattgct tgaattaaac ggcaaaccat
    71101 tatggcaaca tgtcgctgac gcgcttatga cgcagctttc tcacgtcgtg gttaatgcta
    71161 atcgtcatca ggaaatctat caggtaagcg gtctgaaagt gattgaagat tcactggcgg
    71221 attaccctgg ccctctggca ggaatgcttt cagtaatgca gcaggaagcg ggtgagtggt
    71281 ttttgttttg cccgtgcgat acgccttaca ttccccatga tttagccgcc cggcttactc
    71341 atcagcgcaa agatgcgcct gtcgtgtggg tccacgacgg tgaacgcgat cacccgacta
    71401 ttgctctggt aaaccgcgca attgagcctt tattactgga atatctgcaa gcaggagaac
    71461 gccgggttat ggcatttatg cgtctggctg gcggtcatgc ggttgatttc agcgatcgta
    71521 aagaggcatt tataaacgtg aatacgccag aggagcttgc ccgatggcag gaaaaacgat
    71581 gataccgtta ctcgcctttg ctgcatggag tggcaccgga aaaacaacgc tgctgaaaaa
    71641 attgatcccg gcattatgcg ccagagggat ccgtccgggg ctgattaagc atacgcacca
    71701 tgatatggat gttgataaac cgggcaaaga tagctatgag ctgcgcaagg ctggcgcggc
    71761 gcaaaccatc gttgccagcc agcagcgatg ggccttgatg acggaaacac cagacgaaga
    71821 agagctggat ctacattttc tcgcaagtcg aatggatacc tcaaagctgg atttgattct
    71881 ggtcgaaggg tttaagcatg aagagatcgc aaagattgtg ctgtttcgcg atggagccgg
    71941 acatcgaccg gaagaattag tgatagacag gcatgttatt gctgtagcca gtgatgtgcc
    72001 gcttaatctt gatgtcgcgt tactggatat taatgatgtt gaggggctgg ctgattttgt
    72061 ggtggagtgg atgcaaaagc aggacggata agcaagaata ggctgaagca aacgcgccag
    72121 cgtcgcatcc ggcatttatt ccgcacatat gcaaaaaggc ccagtcttcc gactgggcct
    72181 ttcgcttaat ttgatgcctg gcagttccct actctcgcat ggggagaccc cacactacca
    72241 tcggcgctac ggcgtttcac ttctgagttc ggcatggggt caggtgggac caccgcgcta
//
LOCUS       DAPOXO010000013        70823 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPOXO010000013 DAPOXO010000000
VERSION     DAPOXO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 70823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70823
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.013"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            112..675
                     /locus_tag="ROH59_001124"
     CDS             112..675
                     /locus_tag="ROH59_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HDX4803639.1"
                     /translation="MLKKTLLSMFATALLSGVAFNALADDPNQGSGKITFKGEVIDAP
                     CSIAPGDEDQTINLGEVADTVLKSGQKSLPVDVTIHLQDCILSDGTNTVDKVKITFSS
                     ASVDATDSNLLKNTLEGNIGGATDVGVRLVKSDNTNVTLGTPITINFPTTNSYQELNF
                     KARMESLGRTATPGNVQAQANYVLDYK"
     gene            760..3282
                     /locus_tag="ROH59_001125"
     CDS             760..3282
                     /locus_tag="ROH59_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001060675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX4803640.1"
                     /translation="MNNKNTFTGDTLSHAIKNALSGVVCSLLFVLPAHAVEFNVDMID
                     VEDRENIDISRFEKKGYIPPGRYLARVQINKNMLPQALILEWVKADNESGSLLCLTKE
                     DLTSFGLNTEFIESLQTIAGRECLDLSQRQELTTRLDKATMILSLSVPQAWLKYQATN
                     WTPPEFWDTGIAGFILDYNVYASQYAPHHGDSTQNVSSYGTLGFNLGAWRLRSDYQYN
                     QNFADGRSVNRDSEFARTYLFRPIPSWSSKFTMGQYDLSSNLYDTFHFTGASLESDES
                     MLPPDLQGYAPQITGIAQTNAKVTVAQNGRVLYQTTVAPGPFTISDLGQSFQGQLDVT
                     VEEEDGRTSTFQVGSASIPYLTRKGQVRYKTSLGKPTSVGHNDINNPFFWTAEASWGW
                     LNNVSLYGGGMFTADDYQAITTGIGFNLNQFGSLSFDVTGADASLQKQNSDNLRGYSY
                     RFNYAKHFESTGSQITFAGYRFSDKDYVSMSEYLSSRNGDESIDNEKESYVISLNQYF
                     ETLELNSYLNVTRNTYWDSASNTNYSVSVSKNFDIGDFKGISASLAVSRIRWDDDEEN
                     QYYFSFSLPLQQNRNISYSMQRTGSSNTSQMISWYDSSDRNNIWNISASATDDNIRDG
                     EPTLRGSYQHYSPWGRLNINGSVQPNQYNSVTAGWYGSLTATRHGVALHDYSYADNAR
                     MMVDTDGISGVEINSNRTVTNGLGIAVVPSLSNYTTSMLRVNNNDLPEGVDVENSVIR
                     TTLTQGAIGYAKLNATTGYQIVGVIRQENGRFPPLGVNVTDKATGKDVGLVAEDGFVY
                     LSGIQENSILHLTWGDNTCEVTPPNQSNISESAIILPCKTVK"
     gene            3298..4038
                     /locus_tag="ROH59_001126"
     CDS             3298..4038
                     /locus_tag="ROH59_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001374399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDX4803641.1"
                     /translation="MKSPLITTGMICLLGICNFAQATVSPDRTRIIFNASNKSATVRL
                     TNQSKIDPYLAQSWIEDASGKKTRGYISTLPPMERIEPDEQVQIRLMALASLNNLPQD
                     RETLFYYNVREIPPRTKEQNVMQIAMQSRLKLFWRPKAIELKEGQMVPLQKVTITRTA
                     AGLTLNNPTPYHITVGYIGTNGKTLMPGADSIMVTPFASATQYLNNLPSTFQLGFVAD
                     YGGLEMFKVECNSVQSLCQSSPAKKGKI"
     gene            4035..5084
                     /locus_tag="ROH59_001127"
     CDS             4035..5084
                     /locus_tag="ROH59_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein"
                     /protein_id="HDX4803642.1"
                     /translation="MITLFRLLAILCLFYNVSVYAVNCYQDQRGGNTQIRGTLPSFRI
                     PENAQPGQKIWESDDVNVTVYCDNATGWRADDPAENIYAWIKMPAINSADILNNPYLT
                     FGVTYNGVDYEDSDVGIDTFACLDKYEQYYGGIYHDPVCNGSTLQKNVTFNARFRAYV
                     KFKARPAVDQTWDFGVVNVLQFDGEGGANLAADNKNLRYIIDGLNNILFLDCSVDVRI
                     FPESQIVNFGQISANSIATYRPKAAFSVSTIKDVAADCTEQFDVVTSFYTTDTLHDDT
                     HLEMGNGLLMRITDQKTQEDIKFNKYKRFTTYIPGQTGAMVTRDYQAELSQKPGETLV
                     YGPFKKDLIVKINYN"
     gene            complement(5138..5791)
                     /gene="ribB"
                     /locus_tag="ROH59_001128"
     CDS             complement(5138..5791)
                     /gene="ribB"
                     /locus_tag="ROH59_001128"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HDX4803643.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITDDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     regulatory      complement(5895..6043)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            6165..6464
                     /gene="ubiK"
                     /locus_tag="ROH59_001129"
     CDS             6165..6464
                     /gene="ubiK"
                     /locus_tag="ROH59_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311957.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HDX4803644.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRISELEARNNPAAELQSPPAIPPVDKAE"
     gene            complement(6499..6699)
                     /gene="glgS"
                     /locus_tag="ROH59_001130"
     CDS             complement(6499..6699)
                     /gene="glgS"
                     /locus_tag="ROH59_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HDX4803645.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQTRELELEH"
     gene            6969..7598
                     /locus_tag="ROH59_001131"
     CDS             6969..7598
                     /locus_tag="ROH59_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HDX4803646.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEIFALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHACVTLWQSPLPNLF
                     VVPVSLLFTIIAVHYTGKVVAPWIPRDHSSAITEEEYVGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKTFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            7625..9286
                     /locus_tag="ROH59_001132"
     CDS             7625..9286
                     /locus_tag="ROH59_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDX4803647.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLSGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNAKIAAFEA
                     ERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGATGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSSLSSTTPVEEKAE"
     gene            9526..9585
                     /gene="ibsE"
                     /locus_tag="ROH59_001133"
     CDS             9526..9585
                     /gene="ibsE"
                     /locus_tag="ROH59_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsE"
                     /protein_id="HDX4803648.1"
                     /translation="MMKFVIILVVLLLLSFPTY"
     gene            complement(9705..11138)
                     /gene="hldE"
                     /locus_tag="ROH59_001134"
     CDS             complement(9705..11138)
                     /gene="hldE"
                     /locus_tag="ROH59_001134"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HDX4803649.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQLDKKG"
     gene            complement(11186..14026)
                     /gene="glnE"
                     /locus_tag="ROH59_001135"
     CDS             complement(11186..14026)
                     /gene="glnE"
                     /locus_tag="ROH59_001135"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HDX4803650.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQD
                     SVIAHPEWLTELESQPPQADEWQHYAAWLQEALSNVSDEAGLMRELRLFRRRIMVRIA
                     WAQTLALVTEESILQQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSDGVYANELR
                     ALLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSAIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQT
                     QTLPSDELNRARLAWAMDFADWPQLTGVLTAHMANVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLMLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHL
                     ALQELPGHVSEDCFTAERELVRASWQKWLVEE"
     gene            complement(14049..15350)
                     /gene="ygiF"
                     /locus_tag="ROH59_001136"
     CDS             complement(14049..15350)
                     /gene="ygiF"
                     /locus_tag="ROH59_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HDX4803651.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPTDLASRVQPLFSTDFYREKWLVEVDGSRIEIALDQGEVKAGEFAEPICELE
                     LELLSGDMRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHTLMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQSKM
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQ
                     DWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            15592..16212
                     /locus_tag="ROH59_001137"
     CDS             15592..16212
                     /locus_tag="ROH59_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDX4803652.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINRLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPSRKRKDRWMN"
     gene            16276..17514
                     /gene="cca"
                     /locus_tag="ROH59_001138"
     CDS             16276..17514
                     /gene="cca"
                     /locus_tag="ROH59_001138"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HDX4803653.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVSLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALM
                     REMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDSLFGVPA
                     PARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAVASWKEQRCPKPD"
     gene            complement(17594..18415)
                     /gene="bacA"
                     /locus_tag="ROH59_001139"
     CDS             complement(17594..18415)
                     /gene="bacA"
                     /locus_tag="ROH59_001139"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDX4803654.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGENKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(18506..18874)
                     /gene="folB"
                     /locus_tag="ROH59_001140"
     CDS             complement(18506..18874)
                     /gene="folB"
                     /locus_tag="ROH59_001140"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HDX4803655.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            18979..19596
                     /gene="plsY"
                     /locus_tag="ROH59_001141"
     CDS             18979..19596
                     /gene="plsY"
                     /locus_tag="ROH59_001141"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDX4803656.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            complement(19609..20541)
                     /gene="ttdR"
                     /locus_tag="ROH59_001142"
                     /gene_synonym="dan"
     CDS             complement(19609..20541)
                     /gene="ttdR"
                     /locus_tag="ROH59_001142"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
                     /protein_id="HDX4803657.1"
                     /translation="MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQIL
                     ENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGC
                     SFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDAIPDYYIAH
                     LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVK
                     VSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVRVLPEYAQSANIWAVYR
                     EPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM"
     gene            20748..21659
                     /gene="ttdA"
                     /locus_tag="ROH59_001143"
     CDS             20748..21659
                     /gene="ttdA"
                     /locus_tag="ROH59_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HDX4803658.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            21656..22261
                     /gene="ttdB"
                     /locus_tag="ROH59_001144"
     CDS             21656..22261
                     /gene="ttdB"
                     /locus_tag="ROH59_001144"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HDX4803659.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            22309..23772
                     /gene="ttdT"
                     /locus_tag="ROH59_001145"
     CDS             22309..23772
                     /gene="ttdT"
                     /locus_tag="ROH59_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate/succinate antiporter"
                     /protein_id="HDX4803660.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALLPLPAGLESHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHAMLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTIVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTADYWRLGAIFGLIFLVLLVITGLLWMPVVLL"
     gene            complement(23815..24828)
                     /gene="tsaD"
                     /locus_tag="ROH59_001146"
     CDS             complement(23815..24828)
                     /gene="tsaD"
                     /locus_tag="ROH59_001146"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDX4803661.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQEALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     DVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            25066..25281
                     /gene="rpsU"
                     /locus_tag="ROH59_001147"
     CDS             25066..25281
                     /gene="rpsU"
                     /locus_tag="ROH59_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDX4803662.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            25392..27137
                     /gene="dnaG"
                     /locus_tag="ROH59_001148"
     CDS             25392..27137
                     /gene="dnaG"
                     /locus_tag="ROH59_001148"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDX4803663.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVAMSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            27332..29173
                     /gene="rpoD"
                     /locus_tag="ROH59_001149"
     CDS             27332..29173
                     /gene="rpoD"
                     /locus_tag="ROH59_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDX4803664.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDTADDDNSIDPELAR
                     EKFAELRAQYIVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(29251..29757)
                     /gene="mug"
                     /locus_tag="ROH59_001150"
     CDS             complement(29251..29757)
                     /gene="mug"
                     /locus_tag="ROH59_001150"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HDX4803665.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            29882..29957
                     /locus_tag="ROH59_001151"
     tRNA            29882..29957
                     /locus_tag="ROH59_001151"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29915..29917,aa:Ile,seq:cat)
     gene            complement(30011..30775)
                     /gene="nfeF"
                     /locus_tag="ROH59_001152"
     CDS             complement(30011..30775)
                     /gene="nfeF"
                     /locus_tag="ROH59_001152"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase"
                     /protein_id="HDX4803666.1"
                     /translation="MNNTPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEGSRPPSRDYTPLYDELRHELAID
                     FFIHDGGVASGWAMQAKPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFETEQYDPQRVRAAAYWHAK"
     gene            31063..31686
                     /gene="nfeR"
                     /locus_tag="ROH59_001153"
                     /gene_synonym="yqjI"
     CDS             31063..31686
                     /gene="nfeR"
                     /locus_tag="ROH59_001153"
                     /gene_synonym="yqjI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NfeR"
                     /protein_id="HDX4803667.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLCVNQSDITDAQIKKIIAVIDRAAFDITQLD"
     gene            complement(31793..33313)
                     /gene="aer"
                     /locus_tag="ROH59_001154"
     CDS             complement(31793..33313)
                     /gene="aer"
                     /locus_tag="ROH59_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerotaxis sensor receptor Aer"
                     /protein_id="HDX4803668.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTGKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFIVLAAMLWFVAAPVVTYIFCALVMLLGNACFEWQIVRPIENVASQ
                     ALKVATGERNSVEHLKRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQASAMVKHRASRLEDAVTVLH"
     gene            33731..35110
                     /gene="ygjG"
                     /locus_tag="ROH59_001155"
     CDS             33731..35110
                     /gene="ygjG"
                     /locus_tag="ROH59_001155"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417544.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HDX4803669.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAM
                     RTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMA
                     IEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALA
                     AMRVSVEEA"
     gene            complement(35152..35484)
                     /locus_tag="ROH59_001156"
     CDS             complement(35152..35484)
                     /locus_tag="ROH59_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDX4803670.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRIV"
     gene            35703..36686
                     /gene="ebgR"
                     /locus_tag="ROH59_001157"
     CDS             35703..36686
                     /gene="ebgR"
                     /locus_tag="ROH59_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HDX4803671.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLAIELTN
                     CYEHNGLPDIKNVTGILIVGKPTSALRAAACALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYINQGVNRIGFIGGEDLPGKADIREVAFAEYGRLKHVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKLKLRGTTR"
     gene            36870..39962
                     /gene="ebgA"
                     /locus_tag="ROH59_001158"
     CDS             36870..39962
                     /gene="ebgA"
                     /locus_tag="ROH59_001158"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HDX4803672.1"
                     /translation="MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLSL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLIGKQLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSARF
                     DFTVEQPQQWSAESPYLYHLVMTLKDADGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWENVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWFTT
                     LDDYTLHAEVRAEGETLATQQIKLCDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHPIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKM
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAMFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWHYTQENIHAAQHCNELQRSDDITLNLDHQLPGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSQASYEFGAGFFSTNLHSENKQ
                     "
     gene            39959..40408
                     /locus_tag="ROH59_001159"
     CDS             39959..40408
                     /locus_tag="ROH59_001159"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HDX4803673.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDS
                     LTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            40471..41904
                     /locus_tag="ROH59_001160"
     CDS             40471..41904
                     /locus_tag="ROH59_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX4803674.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            42038..43108
                     /gene="ygjJ"
                     /locus_tag="ROH59_001161"
     CDS             42038..43108
                     /gene="ygjJ"
                     /locus_tag="ROH59_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HDX4803675.1"
                     /translation="MKLITAPCRALLALPFCYAFSALGEEARPAEHDDTKTPEMISTS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYDSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLAEGITWMNGLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHDPSDQLFLMQYFYW"
     gene            43125..45476
                     /gene="ygjK"
                     /locus_tag="ROH59_001162"
     CDS             43125..45476
                     /gene="ygjK"
                     /locus_tag="ROH59_001162"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDX4803676.1"
                     /translation="MKIKTILTPVACALLMSFSAHAANADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLISKDVQVEMILRFATPRTSLLETKITSDKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPMQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKYNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDRVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKAWLAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGDKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVANGGKRSDWTVKFAENRSQDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIIERGKGPESWSPLFNGEATQANADAVVKVMLDPKEFN
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFRHAK
                     GLTADGPIQENYNPLTGSQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            45702..47720
                     /gene="fadH"
                     /locus_tag="ROH59_001163"
     CDS             45702..47720
                     /gene="fadH"
                     /locus_tag="ROH59_001163"
                     /EC_number="1.3.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HDX4803677.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDANQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELTHEEILQLIDDFAHCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSM
                     LDLVEGGGTFAEMVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMIEVTGVTLKLNHTVT
                     ADQLQAFDETILASGIVPRVPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGF
                     DTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(47765..48181)
                     /gene="higA"
                     /locus_tag="ROH59_001164"
     CDS             complement(47765..48181)
                     /gene="higA"
                     /locus_tag="ROH59_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HigA"
                     /protein_id="HDX4803678.1"
                     /translation="MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLND
                     PENPLLDLVCAKITAWEESAPEFVEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIG
                     SKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID"
     gene            complement(48178..48492)
                     /gene="higB"
                     /locus_tag="ROH59_001165"
     CDS             complement(48178..48492)
                     /gene="higB"
                     /locus_tag="ROH59_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin HigB"
                     /protein_id="HDX4803679.1"
                     /translation="MHLITQKALKDAAEKYPQHKTELVALGNTIAKGYFKKPESLKAV
                     FPSLDNFKYLDKHYVFNVGGNELRVVAMVFFESQKCYIREVMTHKEYDFFTAVHRTKG
                     KK"
     gene            complement(48777..49913)
                     /gene="rlmG"
                     /locus_tag="ROH59_001166"
     CDS             complement(48777..49913)
                     /gene="rlmG"
                     /locus_tag="ROH59_001166"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HDX4803680.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGPVLILNDAFGALSCVLAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTPDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR"
     gene            49998..50501
                     /locus_tag="ROH59_001167"
     CDS             49998..50501
                     /locus_tag="ROH59_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDX4803681.1"
                     /translation="MSNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNALGLHTAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQDKI"
     gene            50578..51270
                     /locus_tag="ROH59_001168"
     CDS             50578..51270
                     /locus_tag="ROH59_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HDX4803682.1"
                     /translation="MLRAFARLLLRICFSRRTLKIGCLLLLIAGATIFIADRVMVNAS
                     KQLTWSDVNAVPARNVGLLLGARPGNRYFTRRIDSAAELYHAGKVKWLLVSGDNGRKN
                     YDEASGMQQALIAKGVPAKAIFCDYAGFSTLDSVVRANKVFSENHITIISQEFHNQRA
                     IWLAKQYGIDAIGFNAPDLNMKHGLYTQLREKLARVSAVIDAKILHRQPKYLGPLVMI
                     GPFSEHGCPAKE"
     gene            51349..52335
                     /locus_tag="ROH59_001169"
     CDS             51349..52335
                     /locus_tag="ROH59_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDX4803683.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQTQLFLSHKIHVICEKPLASNQAE
                     VDAAIACARENQVVLFEAFKTAYLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFATLVDEHLVNHPGLAVSRITAKLLTEIRRQTGVIFPADNVKL"
     gene            52618..53583
                     /gene="alx"
                     /locus_tag="ROH59_001170"
     CDS             52618..53583
                     /gene="alx"
                     /locus_tag="ROH59_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HDX4803684.1"
                     /translation="MNTVGTPLLWGGFAVVVTIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRVG"
     gene            53907..55151
                     /gene="sstT"
                     /locus_tag="ROH59_001171"
     CDS             53907..55151
                     /gene="sstT"
                     /locus_tag="ROH59_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDX4803685.1"
                     /translation="MTTQHSPGLFRRLAHGSLVKQILVGLILGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVIF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(55155..55706)
                     /locus_tag="ROH59_001172"
     CDS             complement(55155..55706)
                     /locus_tag="ROH59_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HDX4803686.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQRRGIDPFKVEKTPSAVDERG"
     gene            complement(55789..57276)
                     /gene="uxaA"
                     /locus_tag="ROH59_001173"
     CDS             complement(55789..57276)
                     /gene="uxaA"
                     /locus_tag="ROH59_001173"
                     /EC_number="4.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDX4803687.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGEHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIAHLHQLYSVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVEFANGKQTCNERNDFRELAIFKSGVTL"
     gene            complement(57291..58703)
                     /gene="uxaC"
                     /locus_tag="ROH59_001174"
     CDS             complement(57291..58703)
                     /gene="uxaC"
                     /locus_tag="ROH59_001174"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDX4803688.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            59186..60484
                     /gene="exuT"
                     /locus_tag="ROH59_001175"
     CDS             59186..60484
                     /gene="exuT"
                     /locus_tag="ROH59_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexuronate transporter ExuT"
                     /protein_id="HDX4803689.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     VARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVDTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH"
     gene            60614..61390
                     /gene="exuR"
                     /locus_tag="ROH59_001176"
     CDS             60614..61390
                     /gene="exuR"
                     /locus_tag="ROH59_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HDX4803690.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQAADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDARTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            61735..62397
                     /locus_tag="ROH59_001177"
     CDS             61735..62397
                     /locus_tag="ROH59_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX4803691.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKFEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            62401..62784
                     /gene="mzrA"
                     /locus_tag="ROH59_001178"
     CDS             62401..62784
                     /gene="mzrA"
                     /locus_tag="ROH59_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HDX4803692.1"
                     /translation="MQIPRMSLRQLAWSGAVLLLVSTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            62931..63299
                     /locus_tag="ROH59_001179"
     CDS             62931..63299
                     /locus_tag="ROH59_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HDX4803693.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHQKKIAKQKDEVAERQQDLAEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            63337..63642
                     /locus_tag="ROH59_001180"
     CDS             63337..63642
                     /locus_tag="ROH59_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDX4803694.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            63645..64049
                     /locus_tag="ROH59_001181"
     CDS             63645..64049
                     /locus_tag="ROH59_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDX4803695.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            64039..64338
                     /locus_tag="ROH59_001182"
     CDS             64039..64338
                     /locus_tag="ROH59_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HDX4803696.1"
                     /translation="MSSKVERERRKAQLLSQIQQQRLDLSATRREWLEATGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG"
     gene            64525..64917
                     /locus_tag="ROH59_001183"
     CDS             64525..64917
                     /locus_tag="ROH59_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDX4803697.1"
                     /translation="MKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVP
                     GFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGMNSLMFMKN
                     LTISGGFLLLAITGPGAFSIDRLLNKKW"
     gene            64987..65973
                     /gene="yqjG"
                     /locus_tag="ROH59_001184"
     CDS             64987..65973
                     /gene="yqjG"
                     /locus_tag="ROH59_001184"
                     /EC_number="1.8.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionyl-hydroquinone reductase YqjG"
                     /protein_id="HDX4803698.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     KGGFAAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGASGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQPKIDELNGWIYDTINNGVYKAGFATSQQAYDEAVAKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            66256..66624
                     /locus_tag="ROH59_001185"
     CDS             66256..66624
                     /locus_tag="ROH59_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDX4803699.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKLEQE"
     gene            complement(66658..67554)
                     /gene="yhaJ"
                     /locus_tag="ROH59_001186"
     CDS             complement(66658..67554)
                     /gene="yhaJ"
                     /locus_tag="ROH59_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HDX4803700.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIPKLFSGK"
     gene            67659..68360
                     /locus_tag="ROH59_001187"
     CDS             67659..68360
                     /locus_tag="ROH59_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HDX4803701.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASTGEVLLLSTQPGVSYS
                     EHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMSKQQLIASPEGGMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            68383..68547
                     /locus_tag="ROH59_001188"
     CDS             68383..68547
                     /locus_tag="ROH59_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312016.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803702.1"
                     /translation="MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(68608..69918)
                     /locus_tag="ROH59_001189"
     CDS             complement(68608..69918)
                     /locus_tag="ROH59_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDX4803703.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AISDAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNG
                     VVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR"
     gene            complement(69946..>70823)
                     /locus_tag="ROH59_001190"
     CDS             complement(69946..>70823)
                     /locus_tag="ROH59_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="septum formation protein"
                     /protein_id="HDX4803704.1"
                     /translation="SDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALG
                     VSMVGMWHLYNVGSLPPLGLLMKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEV
                     ARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDG
                     AAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKIPAEKINENLVQRGIM
                     IFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLII
                     VTGLLLCVSPFLAFS"
BASE COUNT        17285 a        18658 c        17888 g        16992 t
ORIGIN      
        1 catatctggc cacctctaac tatggtaatc tctctatgca attaatatta aattagacct
       61 gtattaattg tcccattcac agcctatcct aatctataaa ggattatagt catgttaaaa
      121 aaaacattgt tatctatgtt cgcaaccgca ttgttatctg gcgttgcttt taacgcgctt
      181 gctgatgacc caaatcaggg ttctggtaaa ataacattta aaggtgaagt tatcgatgcg
      241 ccttgttcta ttgctcctgg tgatgaagat cagacaataa acctcggtga agttgctgat
      301 actgtattaa aaagcggaca gaaatctctt cctgtagatg tcaccattca cttgcaggat
      361 tgtattttat ctgacggcac taacactgtt gataaagtca aaatcacctt tagttctgcc
      421 agtgttgacg ctaccgactc caacctgctt aaaaacactc tggaaggtaa catcggcggc
      481 gcaactgatg taggcgtacg tctggtgaaa tcagacaaca ccaacgtgac tcttggcact
      541 ccaatcacta tcaacttccc gacgactaac tcctaccagg agttgaactt taaagcccgt
      601 atggaatctc tgggacgcac cgcgaccccg ggtaacgtgc aggcacaggc caattacgta
      661 ctcgactaca agtaagcggc aattaatacg cacaacgtca gacggtaaag ccgatgatat
      721 gtcatcggca actttgggtc ttttttgaaa tggattttta tgaacaataa aaacacgttt
      781 accggggata cattatccca cgcaattaaa aatgccctgt ctggcgtagt gtgttcgcta
      841 ctcttcgttt tacctgccca tgcagtggaa ttcaacgttg atatgattga tgttgaagac
      901 cgtgagaata tcgacatctc tcgttttgag aaaaaaggct atatcccccc aggcagatac
      961 ctcgctcgtg tgcaaataaa taaaaatatg ttgccacaag cgttaatact ggaatgggta
     1021 aaagccgata atgaaagtgg ttcgttactc tgcttaacca aagaagatct gactagtttc
     1081 ggtcttaata cggaatttat tgaatcattg caaaccatag ctggcagaga atgtctcgat
     1141 ttaagccaac gtcaggagtt aacgacacgg cttgataaag ctacgatgat attatcgcta
     1201 agtgttcccc aggcgtggtt aaaataccag gcaacaaact ggacgccacc agagttttgg
     1261 gataccggta tcgccgggtt tatccttgat tacaatgtgt acgccagcca atatgcccca
     1321 catcatggag acagcaccca aaacgtcagc tcctatggta cgttaggctt taacctcggc
     1381 gcatggcgct tacgtagcga ttaccaatat aatcagaatt ttgctgatgg acgctcggta
     1441 aaccgcgaca gcgaatttgc gcgaacttat ctgtttcgcc ctatcccctc ctggtcgtca
     1501 aaattcacta tgggccagta cgacctgagc tccaatcttt acgatacctt ccactttact
     1561 ggcgcatcgc tggaaagtga tgaaagcatg ctgccgccag atttacaggg ttatgcgcca
     1621 caaattaccg gcatcgcgca gaccaacgcg aaagtaactg tggcacaaaa tggtcgtgta
     1681 ctttatcaaa ccactgtcgc gccaggccct tttactattt ctgatttggg gcaatcgttt
     1741 caggggcagc tggatgtcac agtggaagaa gaagatggcc gcaccagcac cttccaggtt
     1801 ggatccgcat ccattcccta tttaacccgt aaagggcaag tgcgctataa aacgtcgctg
     1861 ggaaaaccga catccgtcgg gcataacgat atcaataatc cctttttctg gacggcggaa
     1921 gcctcctggg gctggttgaa caatgtgtcg ctgtatggtg gcggcatgtt caccgctgat
     1981 gattatcagg ctatcactac cggtattggc tttaatctta accaattcgg ttcgctttct
     2041 tttgatgtca ccggagcaga cgcgtctttg cagaaacaaa atagcgacaa tctgcgtggt
     2101 tacagctatc gcttcaacta tgcaaagcat ttcgaatcga caggtagtca gattaccttc
     2161 gcgggttatc gcttctcaga taaagattac gtgtcgatga gtgagtacct aagctcgcgt
     2221 aatggcgatg agtcaattga taatgaaaaa gagagttatg tcatttcctt gaaccagtac
     2281 tttgaaacac tggaattaaa ctcttatctc aacgttacac gcaatactta ttgggacagc
     2341 gccagcaata ccaactactc cgtatctgta agcaaaaact ttgatattgg cgatttcaaa
     2401 ggtatctctg catcgctggc agtaagtcga atccgctggg atgacgacga agagaatcaa
     2461 tattacttct ctttctctct acctttacaa caaaaccgca acatctccta cagtatgcag
     2521 cgtacgggaa gcagtaatac ttcgcagatg atttcctggt acgattcatc agatcgcaac
     2581 aatatctgga atatttcagc gtcggcaacg gacgacaata tacgtgatgg cgaaccaaca
     2641 ctgcgcggca gctaccagca ctattcaccg tggggacgtc tgaacattaa cggcagtgta
     2701 cagccgaatc agtacaattc tgttaccgca ggctggtacg gttcacttac cgctacacgt
     2761 catggtgtcg cccttcacga ttatagctat gctgataacg cccgcatgat ggtcgatacc
     2821 gacggcatct ccggcgttga aatcaactct aaccgaactg ttaccaacgg gctgggcatt
     2881 gccgttgtac cttcgttatc gaactacacc acctccatgt tgcgggtgaa caataacgat
     2941 ctgccagaag gtgtcgatgt cgaaaactcg gttattcgta ctacgctcac ccagggtgcc
     3001 atcggctacg caaaactgaa tgccaccacc ggataccaaa tcgtcggcgt tattcgtcag
     3061 gaaaatggcc gcttccctcc actaggtgtg aatgtcacgg ataaagcgac aggtaaagat
     3121 gtgggcctgg tcgcggaaga cggcttcgtt tatctcagcg gtattcagga aaacagtatt
     3181 ctgcatttaa cctggggtga taatacctgt gaagtcacgc cgccaaacca aagtaacatt
     3241 agcgaaagcg caataatttt accttgtaaa acagtcaaat aattcaggat gaatataatg
     3301 aaatcaccat taatcacaac aggaatgatt tgtttactgg ggatctgcaa ttttgcccag
     3361 gcgactgtct cccccgacag gacacgtatc atttttaatg cttcgaataa aagcgcaacg
     3421 gtccgtctga ctaaccaaag taaaatcgat ccctatctgg ctcagtcgtg gattgaagat
     3481 gccagcggta aaaaaacgcg tggttacata tcaacactgc cgccgatgga acgtattgag
     3541 ccggatgaac aggtacaaat tcgcctgatg gcgctggcct cattaaacaa cttaccgcag
     3601 gacagagaaa cgctgttcta ctataacgtg cgggaaattc cgcctcgcac taaagaacag
     3661 aatgtgatgc aaatcgccat gcagagtcga ctgaaattat tctggcgtcc gaaagcaatc
     3721 gaattaaaag aagggcagat ggtgccttta caaaaagtca caataacacg gaccgctgca
     3781 gggctgacac tcaataatcc aacgccttat cacatcaccg tcgggtatat cggtactaac
     3841 ggcaagacac tgatgcccgg tgcagacagc attatggtga ctccgtttgc ttctgcaact
     3901 caatacttga acaacttgcc ctcaactttc cagttaggct ttgttgctga ctatggtgga
     3961 ctggagatgt ttaaagtcga atgtaattcc gtccaatccc tctgccaaag ctctcctgct
     4021 aagaagggaa aaatatgatt acgcttttcc gtttactggc gattctttgc cttttttata
     4081 acgtttcagt ttatgctgta aattgctatc aggatcaaag aggtggtaat acacaaatac
     4141 gtggtacttt accttccttc agaattccag aaaacgccca gccgggacaa aaaatttggg
     4201 aaagcgatga cgttaatgtt acggtatatt gtgataacgc gacaggatgg agagctgatg
     4261 atcccgcaga aaatatttat gcctggatta aaatgccggc tataaatagt gcagacattt
     4321 tgaataaccc atacctgaca ttcggtgtaa cctataatgg tgtggactat gaagatagcg
     4381 atgtaggaat tgatactttc gcctgtctgg ataagtatga acagtattat ggtggtattt
     4441 atcatgatcc agtttgtaat ggcagcaccc tacaaaaaaa tgtcacgttt aatgcccgtt
     4501 ttcgcgcata tgtgaaattt aaagcacgtc cagcagtgga tcaaacctgg gattttggcg
     4561 tggtaaatgt tctgcaattt gatggtgaag gtggtgctaa cttagcagca gataataaaa
     4621 atctacgtta tattattgat ggattaaata atattttatt tcttgattgt agtgtcgatg
     4681 tccgtatttt tccagaaagc cagatcgtta atttcgggca aatctctgca aactctattg
     4741 ctacttatcg acccaaagct gcatttagcg tatctactat aaaagatgtt gctgccgact
     4801 gtaccgagca atttgatgtt gtcaccagtt tttatacgac agatacgtta catgatgata
     4861 cgcatctgga aatgggtaat ggtttgttaa tgcgtattac tgatcaaaaa acacaagaag
     4921 acattaagtt taataagtac aaacgcttca ccacatatat tccaggtcag actggagcga
     4981 tggttacccg tgattaccag gctgaacttt cacaaaaacc gggggagact ctcgtttatg
     5041 ggcctttcaa aaaagatctc atcgtaaaaa taaactataa ctgaacagca aaatgccggg
     5101 aacaccccgg cattttcata tttagtattt cacgtcatta gctggcttta cgctcatgtg
     5161 cctgacggta tgccaccagg tcttcaatag tcacgagcgc catattgtgt ttattcgcaa
     5221 actcaatgca ctctggtgca cgcgccatcg tgccatcgtc attagtcagc tcacacagca
     5281 caccagctgg tttaaagcct gccagcgtca tcagatcgat agtcgcttca gtatgaccgc
     5341 cacgcgtcag tacaccacct gcctgcgcgc gaagtgggaa aacgtggcct gggcgattca
     5401 gatctgaagg ttttgcgcca tcggcaatcg ctgcgcgaac ggtcgtaata cggtcagcgg
     5461 cagaaacacc ggtagtcaca ccttcagctg cttcaatggt cacggtaaaa ccggtgccat
     5521 aggcgctggt gttattttct accatcattg gcagatcgag ttgtttacgg cgatcgtcag
     5581 taatgcacag gcaaacaata ccactcccgt ggcgaatggt cagcgccatc tgctcaacgg
     5641 tcatggtttc tgccgggaag atcatatcgc cttcgttttc acggtcttca tcatcaagca
     5701 ccatcacacc gcgtccttca cgcagcgcag ccagtgcatt ttcaacacgt tcgaaaggcg
     5761 taccaaaaga ggaaagtagc gtctgattca tggtaaaaaa acctcactaa aattatggtt
     5821 accagaatca gggcagtctt aggagtggcg gcatatagcc aaaataacgt gagcgggtcc
     5881 atgcccgaca gaatcgttac tctctcccat ccggactcta accgtcggcc ccggaattac
     5941 accggatctg ctgtcctttg agttcgcacc caaagcgctc gcgggctttc aactgagttg
     6001 atttaccgcc ggtggggaat ttcgccccgc cctgagaata agcggattca ctataacgct
     6061 aatgattagc gccagcaacg catagcttca cataattctg gtttatgact tacccttatc
     6121 gcactacaat ggcactcaac acctatcagt acagggaaac tacaatgatt gacccgaaaa
     6181 aaattgagca aatcgctcgc caggttcacg aatcaatgcc taaaggaatc agggagttcg
     6241 gggaagatgt ggagaaaaaa atccgccaaa ccctacaagc gcagctgacg cgtctcgatc
     6301 tggtaagccg cgaagaattc gacgttcaga cgcaagtcct gttacggact cgtgaaaaac
     6361 tggcgttact ggagcagcgc atcagcgaac tggaagcgcg caataatccg gcagcagaac
     6421 ttcaatctcc tccggctatc ccgccagttg ataaagcaga ataaagcacc acaaaaacgg
     6481 gccagacggc ccgtaatatc agtgttctaa ttcaagttct ctggtttgca tcatctgttg
     6541 gcaataccag gcataacgtg cgcaaaacca ggttctatgt tcttcatcca tgttaccagt
     6601 aacggccaga atatcgaccg ggcgaccttc tgcgtgcatt ctggcaaaac tacgcgcgag
     6661 aaaatcgaaa ttatttaaag aattaagact atgatccata agcacatcct ccggttattg
     6721 catacctttt aaggccatat gctttttctg atttcagtat tccccaatta gtgtagtgcc
     6781 tttaaacata acgtgcgtaa atatattgtc cccgatcaca ctttttagtg aaaaataaaa
     6841 aaaccatatt aaaagacttt ctcttccaga acttctcaaa catgtgttat tattaacaaa
     6901 gataaaagta atcaaggaaa ctattccaaa gtaaatattg cgtcactaaa tggacattgg
     6961 agtgacatat gattttattc gccgactata acacccctta tcttttcgct atttcctttg
     7021 tactcttgat cggcctttta gaaatttttg cacttatctg cggtcacatg ctctccggtg
     7081 ctcttgatgc acatcttgac cattatgatt ccataaccac aggtcatatt agccaggcac
     7141 ttcattatct caatattgga agattgccag ctctcgtcgt cctctgctta ctcgctggtt
     7201 tttttggtct tattggcatc ctgttgcaac atgcctgcgt tacgctctgg caatcaccac
     7261 tccccaacct gttcgtggtt cctgtcagtt tactgtttac aattattgca gtgcattata
     7321 ccggtaaagt cgttgcaccc tggattccac gcgaccatag ttcagctatt acagaagaag
     7381 aatatgttgg tagcatggca ttaattaccg gccatcaagc cacttcaggt aacccctgcg
     7441 aaggaaaact caccgatcaa tttggccaaa tacattattt gctactggag cctgaagaag
     7501 gaaaaacttt cactaaagga gacaaagtgt taattatttg ccgactttct gcaacgcgat
     7561 atttggcgga aaataatccc tggccccaga tattgtgatt tattaatcaa aaggaaattt
     7621 aataatggat gatatcgtta attctgtgcc ctcctggatg tttaccgcga ttatcgccgt
     7681 atgcattctg tttattattg gaattatttt cgccaggctc tatcgtcgcg cttcggcaga
     7741 gcaagcattt gttcgtactg gtttaagtgg gcaaaaagtg gtgatgagcg gtggcgcaat
     7801 cgtgatgccg atctttcatg aaataattcc catcaatatg aataccctga agctggaagt
     7861 cagccgctca accattgata gcctgattac gaaagatcgt atgcgcgtcg atgtcgtggt
     7921 tgctttcttt gtgcgggtaa aaccttcagt agaagggatt gccaccgccg cccagacgct
     7981 ggggcaacgc accctgtcgc ctgaagactt acgtatgctg gtggaagata aatttgtcga
     8041 tgccctccgt gcaacagcgg cacaaatgac catgcatgag ttacaggata cccgcgagaa
     8101 cttcgtgcag ggagtacaaa ataccgtagc tgaagatctg tcgaaaaatg gcctggaact
     8161 ggaaagcgtt tcacttacca actttaacca gacctcgaaa gaacatttca atccgaacaa
     8221 tgcctttgac gccgaaggtt taaccaaact gactcaggag acggagcgcc gtcgtcgcga
     8281 acgtaacgaa gttgaacagg atgtggaagt cgcagtgcgt gagaaaaacc gtgatgcact
     8341 ttcgcgcaag ttggagattg aacaacaaga agcgtttatg acgcttgagc aggagcagca
     8401 ggttaaaacc cgtaccgctg agcagaatgc gaaaattgcg gcttttgaag ctgaacgtcg
     8461 tcgtgaagca gagcagacgc gaattctggc tgaacgacag attcaggaaa cggaaatcga
     8521 ccgcgaacag gccgtccgct caagaaaggt tgaggccgaa cgtgaagttc gcattaaaga
     8581 gatcgaacag cagcaggtca ccgaaatcgc taaccagacg aaatcgatcg ctattgccgc
     8641 caaatcggaa caacagtccc aggcagaagc gcgtgctaac cttgcactcg cagaagcagt
     8701 aagcgcccaa caaaacgtag aaaccactcg ccagactgcc gaagccgatc gtgctaaaca
     8761 agtggcgttg atcgccgcag cgcaggatgc agaaaccaaa gcggttgaac tgaccgtgcg
     8821 ggcgaaagca gaaaaagaag ccgcagaaat gcaggcggcg gctatcgttg agttagccga
     8881 agctacacgt aaaaagggtc tggcggaagc agaagcacaa cgtgcgctga acgatgctat
     8941 caacgtactt tctgatgaac aaaccagcct taaattcaaa ctggcattat tgcaggcgct
     9001 gcctgcggta attgagaaat ccgttgagcc tatgaagtct atcgacggca tcaaaattat
     9061 tcaggtcgat ggtctgaatc gtggcggcgc tacgggtgat gcaaacacgg gtaatgtggg
     9121 gggcggaaac ctggcagaac aagcgttatc agccgcactc tcttaccgca cacaggcacc
     9181 gctgattgac tccttgctca atgaaattgg cgtttcaggc ggctcactgg cggcattgac
     9241 ttcatcctta agctcaacaa ctcccgtcga agaaaaagca gagtaaaccc tcttctatga
     9301 ataatccctg gcccaaaaag ccggggattt tttatatctg cgttccgcta aaaggtgcaa
     9361 atgatcaggc tgttgcagca ttttgcgtga ctgctcgggg aaggcaaaac tgcctctggg
     9421 aaagcgttgc gcggggtccg gcgctcatca acaatcgggg agtcagcaag gggctgaaac
     9481 gggaaagccc ctcccgagga aggggcctta tagaaggaaa gggttatgat gaagttcgtc
     9541 atcatactgg ttgtgttgtt actgttaagt ttcccgactt actaacaact catcagaggg
     9601 gggagaaatc ctcccttacc cttgttcctt tactttaggt tgaaaaaaca acagcgtcaa
     9661 tagacctgcc tgctacgaag cgagatctgt gaaccgcttt ccagttagcc ttttttatcc
     9721 agttggatct tcttgatgat gttggtcgtc gagcaaccgt cttcaaagtt gagcaccagc
     9781 acttcgccac cgttggccca gacttcttta ctcccggcaa tctcttctgg tttatagtcg
     9841 ccgcctttca ccagcagatc tggcaagatc ccggcgatca agcgctgcgg tgtgtcctct
     9901 tcaaacgaca ccacccagtc gaccgcttcc agtgcgccca gcacaatcat acgctgttcg
     9961 agcgggttaa cggggcggga atcccctttc agccgtttgg tggaggcatc gctgttcaca
    10021 gcgacaatca aacggtcacc cagtttacgg gcatttgcca gataagagac gtgcccggcg
    10081 tgcaggatgt caaagacacc gttggtcatc accacttttt caccgcgttt acgcgctgcc
    10141 gctacagcaa gcttcagttc ctcttcggtc atcacaccaa agccggtatc tgcacgtcca
    10201 cgtactgcgt tttccagctc gatcggcgaa accgtggatg tccccagttt gccgaccacc
    10261 acaccagccg ccgcattggc aaagaagcag gcttcttcca gcgaattacc cgctgccagc
    10321 gttgccgcca ggacgccaat caccgtgtcg cccgcaccgg taacgtcata cacttcctgc
    10381 gcctgggttg gcatatgcag cggcgcttta cccggttgca gcagcgacat accctgttcg
    10441 gaacgggtca ctaacagagc cgagagttcg taatcggcaa tcagtttcat gccgcgctca
    10501 acaatctctt cttcggtctt acatttaccg acaacagctt caaattccga gagattcggc
    10561 gttaacagcg tagcgccgcg gtagcgctca aaatcggtac cttttggatc aatcagcacc
    10621 ggaacacccg ctttacgcgc cagttggatc atctgctgta cgcttgccag cgcacctttg
    10681 gcgtagtcag aaagcaccag cgcgccaatc gaactcagtg cctgattaat ccgctcgtgc
    10741 agcggctgcg gatcaacccc ttcgaaacct tcttcgaaat ccagacggat cagctgttgg
    10801 ttacgggaaa gtacccgtaa tttggtgata gtcggatgcg tcggtacaga aacaaagtcg
    10861 catttaacgt tgacgtcggc cagagattta ctgagcgcgc gcgccgcatc gtcaatgccc
    10921 gtcaacccga ccaggcgtgc attagcaccg agagaagcga tattcatcgc cacgttagcc
    10981 gcgccgcccg gacgttcttc gatggtattc actttaacca cgggtaccgg cgcttccggc
    11041 gagatacggc tggtgggacc gtaccagtaa cgatccagca tcacatcacc aaccaccatc
    11101 actcctgcac gttcaaactc tggcagcgtt actttcattc ctgtctcctg agagattcaa
    11161 aatttgcgcg cgataatacc atacttcatt cttccaccag ccacttctgc cagcttgccc
    11221 gcaccagttc acgctctgcg gtgaagcaat cctccgacac atggcccggc aattcctgta
    11281 atgccagatg atgaagttca tcgcgcagcg tcgtgtaagc acgggtcagc gccatcgctt
    11341 cctgctcttc cataatgtcg ttttgcgcca gtagttccag aatgcgcacg ttgtctgacc
    11401 agcgcgttaa cttcggtttt tcgtgagcgt agcgcaacac cagatattga gtaataaatt
    11461 cgatatcggt aattccgcct tcatcggctt tgatatcaaa gcgatcgcga tgtttattgc
    11521 cgagatgggc acgcattttc tcgcgcattt cccgcacttc tgtttgcagg gttttgcctt
    11581 cgcgcggcag cgtcataatc tcccggcgta ctgcgtcaaa gtgcgcggtg agctgcggat
    11641 cgccgtacac tacacgcgca cgcaccagcg cctgatgctc ccacgtccag gcctcgtttt
    11701 tctgataatc agcaaatgct tctgcggatg tcaccagcat tcccgccgcc ccggacggac
    11761 gcagtcgtgc atccacttca tacaaaatgc cggaagaggt tcgcgtactg aacagatgca
    11821 taatgcgttg cgccagacgc agataaaact gtcgcccgtc gatttcccgc tcgccgtcag
    11881 tcatcgcatc cattgggcaa tcatggagga agatcaggtc aagatcggaa ctgtagccta
    11941 actcccagcc acccagcttg ccgtagccga ccaccgcaaa accacgccct tcgcgttcgt
    12001 tcaggtgatt tggcttaccg tagcgggcaa ccatttgaac ccacgcctgc tgaacgacgg
    12061 catcaatcat ggcttctgcc agccaggtta agtgatcgct cactttcatt accggtagcg
    12121 taccggcgat atccgctgcc gcaatgcgta acagctgcgc ctgtttgaac tgacgcagcg
    12181 cctcaagctg ttgttcttcg tcatcttccg gcacgcgcag caaatactgg cgcagttcat
    12241 cacggtaggc atccgtcgcc gttggttggt agagggtatt tggatcgagc aattcatcca
    12301 gcaataatgg ataacgcgct agctggctgg caatcatcgg cgatgcagca cacagagaaa
    12361 tcaaatgctt aagcgccgca gggaattcac taagcagctc aagataagtg gtgcgagtaa
    12421 caatccccac cagcaaggcg gtaatgcgcg acagcgtgac agcagcgtct tcacgcgcac
    12481 agacatcact tagcagatgt ggcatcagat ggtcgagcac ctgacgtcct cgcggcccga
    12541 tggtgcgctt atccagctct ttgcggaaat cagcaatcag cattagcacc tgtttgcgat
    12601 catcctcgct aagatgcgcc agcactggcg tggtgtcatc ttcctgcaac gcatcctgcc
    12661 acagctcacg ccactgttcc gacagcgact cttcctgagt ttcactttcg tcgtcgccaa
    12721 tcaattcatt aaacacccgg cgcacattgg ccatatgtgc ggtcagcacc ccggtcaatt
    12781 gcggccagtc agcaaagtcc atcgcccacg ccagccgcgc acggttaagc tcatcagaag
    12841 gaagcgtctg ggtttgttcg tcgttaatgc tttgcagcag gttttccaga cgccgcagga
    12901 acagatacgc cactcgcaat tgttcagcat cgttttcaga aagcagatgc agcgcggcaa
    12961 tggcgctgag cgttggcagt aaagagcgcg attgcagcga cggttcgcgc ccgccgcgaa
    13021 tgagctggaa cacctggacg ataaattcaa tttcgcgaat gccgcctgcg ccaagtttga
    13081 tgttgtcggt caaaccgcgt cgacgcactt cacgggcaat cattcctttc atgttgcgca
    13141 gcgactgaat cacgctgaaa tcgatgtaac gacggaaaac aaacgggcgc agcaacgcac
    13201 gcaactcgtt agcatagacg ccgtcgctat cccccataat ccgcgccttg accatcgcgt
    13261 aacgctccca gtcgcgcccc tgctcctggt aataatcttc cagcgccgca aagctcagca
    13321 ccagcgggcc actttcccca aacggacgca gccgcatatc cacgcgatag acgaagccat
    13381 cctgcgttgg ttgatccagt actttaatca gccgctgccc catgcgggta aaaaactgcg
    13441 cgttatccag ttcccggcgt ccgccctggg tacaaccatg ttccggccag gcaaaaatca
    13501 gatcgatatc tgaggagaaa ttcaattccc cgccgcccag cttacccatg cctaaaatca
    13561 gcagcggttg cgcttcgccc tgcgcattgc acggcgttcc ccattcgcgg cagcaggcgt
    13621 catacagcca gtcacgcgcc gcaacaatca gcgtctccgc cagatggctg agctgctgca
    13681 atatgctctc ttcagtaacc agtgccagcg tttgcgccca ggcgatgcgc accataatgc
    13741 gccgccggaa tagccgcagc tcgcgcatta acccagcctc gtcactcaca ttactgagcg
    13801 cctcctgcaa ccatgcagcg taatgctgcc attcgtcggc ctgcggcggt tggctttcca
    13861 gttccgtcag ccactctgga tgcgcaatca cgctgtcctg cacaaaatca ctgaaagtaa
    13921 gtactgactt cgcctgtgcg ctaagtgatt cctcggctaa aggctctggc agccgctcaa
    13981 caacggtctg ccagtactgc tgtaacggtg aagagagcgg cttcataagc gattttatcc
    14041 ttgcctgatt aacgttttcc gctgtgcaac cagaacggtt cctgattgtt tgcctcatta
    14101 cggaaatgtt caatttcaat gcgttgcccg gtcgcaatag cgtgacgcag cccctgccag
    14161 ttctccagcc agtcttgcgc gacgacagga tcgtagtaac ccgccagcaa cagtattgag
    14221 tcaatatcac gcgtcaggcg tggcaattgg tcacggtagc gatcgcctaa cggctggcag
    14281 aaaacgcttt tcagttcagc ggcatggcgg gaaagatgga tatcggcaaa gcgtttgaag
    14341 gaatcgctca ttttactctg cgctttggca tctaaaaacg gctgccaggc tttgcttacc
    14401 agccattcgg tcaacgccag cttcgccatt gccgtttcgg tagagtagac cgccgttacg
    14461 gcagaaaccg cagaagcaat ggtcgcctcg cattgagtca gcagatcacg taagtgagtg
    14521 ctcgctttac gcggcacaat gccaccgaac agcatcagtg tatgacgaac caggccaatg
    14581 gctgccagca cctgctcttt cgccgcatcg ttgccgcgta cccacagttc ttcatgatac
    14641 tgccattgcg ctaacgccag ctcgagcgcc gcttccagcc cctgttccac atcagctttt
    14701 gccgcaacat gcaaaatggt ggtcggtttg atttcacgcg ccggattgcc ctgcgccaga
    14761 tgatagccac gcgctgcttt gctcaggctg ccctggcgta atccggtttg cgataccagt
    14821 tggttcgcca gtttcagcac cgcacgcatg tcgccgctaa gcagttccag ttccagctca
    14881 cagataggtt cagcaaattc acccgctttc acctcaccct gatcgagagc gatttcaatt
    14941 cggctgccat cgacctctac tagccatttt tcgcgataaa aatcggtgct aaacagcggc
    15001 tgcacgcggg aagcgagatc ggtaggcaat tcgccgttcg gccagacttc cgtcggtaac
    15061 tgcgccaggt cgagcgtcgg ttcgctcaac gccacgttat attccgggcg ctggtgtaag
    15121 ccgcctgtca ctcttcctgc aactttcatg gtcatctcat agcgaccgtt ttcgccacga
    15181 atacgcaagc ccatgtcgtg cccacgcagc caattatccg gcgtttcgta gtaaatattc
    15241 agcaactgca cggggtcatg gtgctcgccg cccagcgtat tgagatggtc acgcagcgcc
    15301 tcaacggcac tgtgattaac aataaacttt aattcgattt cctgagccat ggcctttact
    15361 tactggttat gtcacataag tgacgatgaa cggcgaactt aatgcgatct tttttgtcag
    15421 tagatagtat tttgcgccaa attgccatgc aacgggcaat ttgacgggcg taaaagtttg
    15481 aagcagtggc aagacctgac acagaggatt ccgattgatg tcgaatgctt tgcgtagcga
    15541 cactgatgcc actactatcg ttccactttc catgacaata acgacagcct gatgccaaaa
    15601 ttacgcctga tcggattaac tttactcgca cttagcgcga ctgccgtctc acacgctgaa
    15661 gaaacgcgct atgtttccga cgaactgaat acctgggtcc gtagcggtcc gggagatcat
    15721 tatcgcctcg tgggcacggt taacgccggc gaggaagtga ccttattaca aactgacgcc
    15781 aacaccaatt atgcccaggt gaaagacagc tctggccgta ctgcctggat cccgttgaaa
    15841 caacttagca ctgaaccaag cctgcgctcc cgtgtgccag atctggaaaa tcaggtcaaa
    15901 actctgaccg ataaactcac caatatcgat aacacctgga atcagcgcac cgcagaaatg
    15961 cagcaaaaag tggcgcagag tgacagcgtg atcaacaggt taaaagaaga aaatcagaaa
    16021 ctgaaaaacg agctgattgt cgcgcagaaa aaggtcgatg ccgccagcgt acagttggat
    16081 gacaaacagc gcaccatcat catgcagtgg tttatgtatg gcggtggcgt gctggggctt
    16141 ggcttgctgc ttggtctggt actgccgcac ctgatcccaa gccgcaaacg caaagatcgc
    16201 tggatgaact aaatcgcctt cttcgttgca ctgtcttatt attaggaatt gtgtatttga
    16261 cgaagggatg atggcgtgaa gatttatctg gtcggtggtg ctgttcggga tgcattgtta
    16321 gggctaccgg tcaaagacag agattgggtg gtggtcggca gtacgccaca ggagatgctc
    16381 gacgcgggct accagcaggt aggccgcgat tttcctgtgt ttctgcatcc gcaaacgcat
    16441 gaagagtatg cactggcacg taccgaacgg aaatctggtt ccggttacac cggttttacc
    16501 tgctatgccg caccggatgt ctcgctggaa gatgatctta agcgtcgcga tctgaccatt
    16561 aatgcgctgg cccaggacga taacggcgag attatcgacc cgtacaacgg tctgggcgat
    16621 ctgcaaaatc gtctgttgcg ccatgtttcc cccgcttttg gcgaagatcc gttacgcgtg
    16681 ttgcgcgtag cgcgttttgc tgcgcgttat gcccacctca gtttccgtat tgccgatgaa
    16741 actctggcgc tgatgcgcga gatgacccat gcgggtgaac tggaacacct gacgcctgaa
    16801 cgggtatgga aagagacgga aagcgccctc accacccgca atccccaggt gttcttccag
    16861 gtactgcgcg attgcggcgc actgcgcgtt ttattcccgg aaattgactc cctgtttggc
    16921 gttccggccc ctgccaggtg gcacccggaa atcgacacgg gtattcatac cttaatgacg
    16981 ctctcaatgg cggcgatgct gagtccgcag gtcgatgttc gtttcgcaac gttatgccac
    17041 gatctcggta aaggactgac gccgccagaa ctttggccac gtcatcatgg tcatggcccg
    17101 gcgggtgtga agttagtgga acaactatgc cagcgtctgc gcgtgccaaa tgaaattcgc
    17161 gatttagcca gactggtagc tgagtttcac gatctcatcc acacctttcc aatgctgaac
    17221 ccgaaaacca ttgttaaatt gtttgattcc attgacgcct ggcgtaaacc gcagcgtgtc
    17281 gagcaactgg cgctgaccag cgaggctgac gtgcgcggca gaaccggttt tgaatcagcg
    17341 gactacccgc aaggccgctg gttgcgcgaa gcctgggaag tggcgcagtc agtgccgaca
    17401 aaagccgtcg ttgaagcagg atttaaaggt gtggagattc gtgaggagct gacccgacgg
    17461 cggattgcgg cggtagccag ctggaaggaa caacgttgcc caaagcctga ttaacttttt
    17521 aaattcagta tattgcagaa atcccttagg tcggataaga cgcacaagcg tcatatccga
    17581 cactatctct caatcaaaag aacacgacgt acaccgcagc cgccacaata aagcgataaa
    17641 tggcgaacgg gataaacgaa atgcgcttaa tcaattgcag gaaggtttta atcgctatca
    17701 gcgccaccac aaaagcggtg ataaacccaa cggcaaacat cgggatatcg ccggtagtca
    17761 ggaagcccca gcttttgtag agatcgagcg ccgttgcgcc catcatcatc ggcaccgcca
    17821 gcaggaacga gaactcggaa gcagcgtaac ggctcacccc catcagcatc ccacctgaaa
    17881 tggtcgcccc ggaacgggag aaacccggcc acagcgccag acactggaaa cagccaatca
    17941 taaacgcctg acgataggtc atatcatcaa gacccggcgc acgcggctct ttcggcttca
    18001 ggcattcggc agcaatcagc aacagaccgc caacgaccag tgcatacatg acatttatcg
    18061 ggttaaacaa tgatttaatc gtgtcgtgga acaacagccc cagtaccacc gccggaatca
    18121 tccccagcaa aatgtggatc agcgttaaac gacctttgtt ttctccttcg tgctgcaacg
    18181 ggcggccaaa gtggatgcca atcaggccaa acagacgccg ccagaacatc actactaccg
    18241 ccagaattga tcctaactgg atcacgactt caaaggtttt cgccgtgtcg ccctcaaacc
    18301 ccaacaagtg accgacaata atcatatggc ccgtgctgga taccggcaga aattctgtca
    18361 atccttcgac cacacccaat attgccgcta tcagcagcga gtgcatatcg ctcatcaata
    18421 aacccctaaa ttataaaaat gtaacgcttg tccgaactac tgcagtatga ccaggttata
    18481 atcgtttggt ttaacagctg taaaattaat tattttcttt cagattattg ccacgctcaa
    18541 tgattacgcc aacattcgcc gcccgcgcca ctgcgcctgg cttgctgagt ttgatacgca
    18601 cccacggcga gttgaagcgt gctaacagca gttccgccac ctcttcagcc acgcgttcca
    18661 ccagcgcaaa acgcgccccc tcgacgtggc tgaccaccgt ttctgcaatg tcagcgtaac
    18721 tgaggcaatc cgccacatca tcacttttcg ccgctttacg gttatcccac gccatttcga
    18781 tatcgaacac taacttctgt tcgatggtct gttcccagtc gtaaacacca atagtggtga
    18841 ttaccgaaag ttgctctata aatacaatat ccatcacgtc ctgcctgctt tttggctaac
    18901 cggataccac ttccggcgaa atgtgcgtat tatccacaga ttcatcgttg aacacgaatt
    18961 ttcaaaacgg aacagcttat gagtgcaatc gcgcctggaa tgatcctcat cgcgtacctc
    19021 tgcggctcca tttccagtgc cattctggtt tgccgcttgt gtgggttacc cgatccgcga
    19081 accagcggct ccggcaatcc aggcgcaacc aatgtgttac gtatcggtgg caagggagca
    19141 gccgtagcag tactgatttt cgacgttctg aaaggaatgt tgcccgtctg gggcgcgtat
    19201 gaattaggtg tcagcccctt ctggctaggc ttaattgcca tcgccgcctg tcttggacac
    19261 atctggcccg ttttcttcgg ttttaaagga ggaaaaggcg ttgctaccgc ttttggtgcc
    19321 atcgcaccaa ttggctggga tctcactgga gtaatggcgg gaacctggtt actgaccgtg
    19381 ctattgagtg gttactcgtc gctgggagcg attgtcagtg cactgattgc tccgttttat
    19441 gtctggtggt ttaagccaca attcaccttc ccggtttcga tgctctcttg cctgatcctg
    19501 ctgcgtcatc atgacaacat ccagcgtctg tggcgtcgcc aggagacaaa aatctggacg
    19561 aaattcaaaa gaaagcgcga aaaggatccc gagtgatttc tggtggatct acatgacctg
    19621 atagccttcg tcgggcttgc ccagccgttg ctggcaccat gccgccagaa attccacaca
    19681 gacacgtaat ttcatgctgc gatagagcgg ctcccggtaa acagcccaga tattggcgct
    19741 ttgtgcatac tccggcaata ctcgcaccag tttgccactc tccagaaacg gcaacacatc
    19801 ccactcggaa cgcagcataa tccctttgcc ctccagcgcc cattgcaaca caatctcgcc
    19861 gctattggag gaaagatgtc cgcttacctt caccgatttt ttctcctgac cgttccccaa
    19921 ctcccatatt ccgtgggtca tatcgcgctc tttggtcacc aggcagtcat gacgacttaa
    19981 ttcctgtaag gattgtggct gcggatattt ttgcagatac tcaggtgctg cgcataatat
    20041 tcttttattt tttgtcaaaa gatgcgcaat ataataatca ggaattgcgt cattaatacg
    20101 aatatccaga tcaatattat cctgcactaa atcaatttgt cgatcgaaca attcaaaatg
    20161 cacctgtaac tcaggataat tgcgcatcag ttcggtaata gctggcgcaa tatggctgcg
    20221 cccaaaacca aaactgcaac caatgcggat catcccctcc gggcgcgttt tgatttgcgt
    20281 gacgtcatcg accagtcgct gatattgggt gaggatttcc agcgcatgtt cgtaacaacg
    20341 ttggccactt tcagtcagcg ccacgccgcg agcggagcgg ttcagcagcg ttgttgccag
    20401 cgtattttca aggatttgga tccgcttggt gacaaatgca ggcgtttgcc caagcgtcgc
    20461 cgctgcagca ctaaaactcc cgctatggac gatttccacc agtacctgca agtctttggc
    20521 taaaggccag ctatttagca ttgttaaata tccgcagttt tgataaacgc agtgtatttc
    20581 gcaaaacatt accattccct gctctggcgc aatattcgtt cttattttcg cgttgattca
    20641 cgaactgtta attacatatt cacggtggca aaaaatataa aaccacattt ttagtggtag
    20701 tttgtggcgg tgaatttttc cagacaaata cataaactgg agttgccatg atgagcgaaa
    20761 gtaataagca acaggcagtg aataagttga cggagattgt cgctaacttt accgccatga
    20821 tttctacccg aatgcctgat gacgtggtgg ataaactaaa acagctaaag gatgccgaaa
    20881 catcgtcgat gggaaaaatc atctaccaca cgatgttcga taacatgcaa aaagcgatcg
    20941 acctgaatcg tcctgcctgt caggacaccg gcgaaatcat gttttttgtt aaggtcggtt
    21001 cccgtttccc actgcttggc gagctgcaaa gcatactcaa acaagccgtg gaagaggcaa
    21061 ccgtcaaagc gccactgcgt cacaatgcgg tagaaatttt tgacgaagta aacaccggca
    21121 aaaataccgg cagcggcgta ccgtgggtca cctgggatat cgtccccgac ggtgacgatg
    21181 cggaaatcga agtttacatg gcaggcggcg gctgcacgct acctggccga tcgaaagtgt
    21241 taatgccgtc agaaggctac gaaggcgtag tgaaattcgt cttcgaaaat atctccaccc
    21301 tcgccgtaaa cgcctgtccg ccggtactgg tgggcgttgg catcgctacc tcggtggaaa
    21361 ccgccgcagt gctctcgcga aaagccattt tgcgcccgat tggcagccgc caccccaatc
    21421 cgaaagcggc agagctggag ctacgcctgg aagaaggact caaccgtttg gggattggtc
    21481 cacaagggct gactggcaac agttcagtga tgggcgtgca tatcgaatct gccgctcgcc
    21541 atccgtcaac catcggcgtt gctgtttcta ccggctgctg ggcgcatcgt cgcggcacac
    21601 tgctggttca tgccgatctc acctttgaaa atctgtctca cacccggagc gcgttatgaa
    21661 aaagatcctg acaaccccga tcaaagctga agatctgcaa gatattcgcg tcggcgatgt
    21721 gatctacctg accggtacgc tggtgacctg ccgtgacgtt tgtcaccgtc gcttgatcga
    21781 actgaaacgt ccgatccctt acgatctcaa cggcaaagcg attttccacg ctggccccat
    21841 cgtgcgcaaa aacggcgaca aatgggagat ggtatccgtc ggcccgacaa ccagtatgcg
    21901 tatggaaagt tttgaacgtg aatttatcga gcagaccggc gtgaaactgg tggtcggcaa
    21961 aggcggaatg gggccgctga ccgaagaagg ctgccagaaa ttcaaggcgc tgcatgtgat
    22021 tttcccggct ggctgtgcgg tactggcggc aactcaagtg gaagagattg aagaagtgca
    22081 ctggacagaa ctcgggatgc cagagtcgct gtgggtctgc cgggtcaaag agtttggccc
    22141 gctgattgtc tctatagata cccacggcaa caacctgata gccgaaaata aaaagctgtt
    22201 cgccgaacgc cgcgatccca tcgtggaaga gatctgcgag cacgtccact acatcaaata
    22261 accctcacgg agaggctcgc ccctctcctt tttcgcaggc ataacacgat gaaaccttcc
    22321 actgaatggt ggcgatacct tgcgccgctg gcggtcatcg ccattattgc tctacttccg
    22381 cttcccgcag ggctggagag tcatacctgg ctctactttg ccgtttttac tggcgtgatc
    22441 gttggactga tcctcgaacc cgtgccgggt gccgtggtgg cgatggtggg tatatccatc
    22501 atcgccattc tttcgccgtg gctgctgttt agcccggagc agctcgccca gccaggtttt
    22561 aagttcaccg ccaaatccct ctcctgggcg gtttctggtt tttctaattc agttatctgg
    22621 cttattttcg ccgcctttat gtttggtacg ggctatgaaa aaaccgggct tggacgtcgc
    22681 atcgcgctga ttctggtgaa aaaaatgggg catcgcacgc tgtttctcgg ctatgcagtg
    22741 atgttctccg agctgatact cgcgcctgta acaccgtcca actcggcgcg tggtgcgggg
    22801 attatctatc ccatcatccg taacctgcca ccgctctatc aatcacaacc aaacgacagc
    22861 agttcgcgca gcattggctc gtacatcatg tggatgggga ttgttgccga ctgcgtgacc
    22921 agcgccattt tcctgacggc gatggctcca aatttgctgt taattggact gatgaaaagc
    22981 gcatctcacg ccatgctaag ctggggcgac tggttcctcg ggatgttgcc gctcagcatt
    23041 ttactggttt tgctggttcc ctggctggct tacgtgctgt acccgccggt actgaagtct
    23101 ggcgatcagg tgccgcgctg ggcagagacg gaactgcagg caatgggccc gctctgttcg
    23161 cgtgaaaaac ggatgctggg gctgatggta ggcgcactgg tgttgtggat ttttggcggt
    23221 gattatatcg atgccgcgat ggtcggttac agcgtggtgg cgctgatgct gcttctgcgc
    23281 attatcagtt gggacgacat tgtcagtaat aaagcggcgt ggaacgtttt cttctggctg
    23341 gcctcgctta tcaccctcgc taccggactc aacaacaccg gttttattag ctggtttggc
    23401 aaactgttag caggcagctt aagcggttat tcgccaacga tagtgatggt ggcgttgatt
    23461 gtggtctttt atctgctgcg ctactttttt gccagcgcca cagcgtatac ctccgctctc
    23521 gcaccgatga tgattgccgc cgcgctggcg atgccggaaa tcccgctgcc ggtgttctgc
    23581 ctgatggttg gtgcggcaat tggtctgggg agcattctta caccatacgc caccggaccc
    23641 agtccgattt actacggcag tggttatctg ccaacggcgg attactggcg actgggggcg
    23701 atttttgggc tgatattcct cgtattgctg gtgattaccg gcttactgtg gatgcccgtg
    23761 gtgttgcttt aagtgaggac ggtgccggaa attgctctcc ggcacccaat agttttacgc
    23821 ggccggtaac tctgccagtg gccagcgcgg acgcacactc acgccgagat ccgccgtcgc
    23881 gcctgcttta aaccgcacca ttccggcata ggcgatcatc gcaccgttat ccgtacaaaa
    23941 ttccggacgc gcgtagaaca cttcgccacg gcgttttttc atcatttccg ccagtttcgc
    24001 ccgcaacgtg cggttagcac tcacgccgcc tgccatgacc agtcgcttaa agcccgtctg
    24061 atccagtgct cgcttacact taatcatcaa cgtatcgacc actgcatctt caaaggcgcg
    24121 ggcgatatcg gcacgcgtct gatcgtcagt gccgttgtca cgtatggtat ttgccgcgaa
    24181 ggttttcaga ccagaaaagc tgaaatccag ccccggacgg tcggtcatcg gacgcgggaa
    24241 aacaaagcgc ccggcagtac cctgagccgc cattttagac agtaacggtc cgccaggata
    24301 atccagcccc agcagcttcg cggttttatc aaacgcttca ccagcagcat catcgataga
    24361 ctcgccgagc agctcgtact gaccaatgcc agtcacgctg attaactgcg tatgaccgcc
    24421 ggaaaccagc agcgcgacaa acggaaattc cggtgggtta tcttccagca tcggcgctaa
    24481 cagatgtcct tccatatgat gtaccgggat tgccggaacg tcccaggcaa acgccagaga
    24541 acgccccacg gtcgcgccaa ccagcagtgc gccgactaat cctgggcctg cggtataggc
    24601 cacagcatca atgtcttttg ccgttaaacc agactccttt agcgcctcct ggatcaacgg
    24661 tacggtttta cgcacgtgat cgcgggaggc cagttcaggc acgacgccgc cgtagtcagc
    24721 gtgcaatttc acctgactat acaattggtt ggctaacaaa cctttttcat cgtcgtaaat
    24781 ggcgatgccg gtttcatcgc aggaagtttc aatacccagt acacgcatga cttgttttac
    24841 ctcgctttat taccgcgcag tgtaggacca atgcgggttg atgtaaaact ttgttcgccc
    24901 ctggagaaag cctcgtgtat actcctcacc cttataaaag tccctttcaa aaaaggccgc
    24961 ggtgctttac aaagcagcag caattgcagt aaaattccgc accattttga aataagctgg
    25021 cgttgatgcc agcggcaaac cgaattaatc aaaggtgaga ggcacatgcc ggtaattaaa
    25081 gtacgtgaaa acgagccgtt cgacgtagct ctgcgtcgct tcaagcgttc ctgcgaaaaa
    25141 gcaggtgttc tggcggaagt tcgtcgtcgt gagttctatg aaaaaccgac taccgaacgt
    25201 aagcgcgcta aagcttctgc agtgaaacgt cacgcgaaga aactggctcg cgaaaacgca
    25261 cgccgcactc gtctgtacta attccccgag agcgttgctc tccgatcaga ccgagttgta
    25321 gttgtaaggc cgtgcttccg aaaggaatgc gcggcttatt ttcgtttatg aattgctaaa
    25381 aatcggggcc tatggctgga cgaatcccac gcgtattcat taatgatctg ctggcacgca
    25441 ctgacatcgt cgatctgatc gatgcccgtg tgaagctgaa aaagcagggc aagaatttcc
    25501 acgcgtgttg tccattccac aacgagaaaa ccccgtcatt caccgttaac ggtgagaaac
    25561 agttttacca ctgctttgga tgtggcgcgc acggcaacgc gatcgacttc ctgatgaact
    25621 acgacaagct cgagttcgtc gaaacggtcg aagagctggc agcaatgcac aatcttgaag
    25681 tgccatttga agcaggcagc ggccccagcc agatcgagcg ccatcagagg caaacgcttt
    25741 atcagttgat ggacggtctg aatacgtttt accaacaatc tttacaacaa cctgttgcca
    25801 tgtctgcgcg ccagtatctg gaaaaacgcg gattaagcca cgaggttatc gctcgctttg
    25861 cgattggttt tgcgcccccc ggctgggaca acgtcctgaa gcggtttggc ggcaatccag
    25921 aaaatcgcca gtcattgatt gatgcgggca tgttggtcac taacgatcag gggcgcagtt
    25981 acgatcgttt ccgcgagcgg gtgatgttcc ccattcgtga taaacgcggt cgggtgattg
    26041 gttttggcgg acgcgtgctg ggcaacgata cccccaaata cctgaactcg ccggaaacgg
    26101 acattttcca taaaggccgc cagctttacg gtctttatga agcgcagcag gataacgctg
    26161 aacccaatcg tctgcttgtg gtcgaaggct atatggacgt ggtggcgctg gcgcaatacg
    26221 gcattaatta cgccgttgcg tcgttaggta cgtcaaccac cgccgatcac atacaactgt
    26281 tgttccgcgc gaccaacaat gtcatttgct gttatgacgg cgaccgtgca ggccgcgatg
    26341 ccgcctggcg agcgctggaa acggcgttgc cttacatgac agacggtcgt cagctacgct
    26401 ttatgttttt gccggatggc gaagaccctg acacgctggt acgaaaagaa ggtaaagaag
    26461 cgtttgaagc gcggatggag caggcgatgc cactctccgc atttctgttt aacagtctga
    26521 tgccgcaagt tgatctgagt acccctgacg ggcgcgcacg tttgagtacg ctggcactgc
    26581 cactgatatc gcaagtgccg ggcgaaacgc tgcgaatata tcttcgtcag gaattaggca
    26641 acaaattagg catacttgat gacagccagc ttgaacgatt aatgccaaaa gcggcagaga
    26701 gcggcgtttc tcgccctgtt ccgcagctaa aacgcacgac catgcgtata cttatagggt
    26761 tgctggtgca aaatccagaa ttagcgacgt tggtcccgcc gcttgagaat ctggatgaaa
    26821 ataagctccc tggacttggc ttattcagag aactggtcaa cacttgtctc tcccagccag
    26881 gtctgaccac cgggcaactt ttagagcact atcgtggtac aaataatgct gccacccttg
    26941 aaaaactgtc gatgtgggac gatatagcag ataagaatat tgctgagcaa accttcaccg
    27001 actcactcaa ccatatgttt gattcgctgc ttgaactgcg ccaggaagag ttaatcgctc
    27061 gtgagcgcac gcatggttta agcaacgaag aacgcctgga gctctggaca ttaaaccagg
    27121 agctggcgaa aaagtgattt aacggcttaa gtgccgaaga gcgatcggga agcccccgac
    27181 agccgcactg agaggcagcg gcaaatatat aagtacgccc tcgtaattat cgttggcggt
    27241 aaacaaccgt tggatttcag cgttaacggc tgaaggacat cgggtcaatc gcccaacacc
    27301 aacctcatga aataagtgtg gataccgtct tatggagcaa aacccgcagt cacagctgaa
    27361 acttcttgtc acccgtggta aggagcaagg ctatctgacc tatgccgagg tcaatgacca
    27421 tctgccggaa gatatcgtcg attcagatca gatcgaagac atcatccaaa tgatcaacga
    27481 catgggcatt caggtgatgg aagaagcacc ggatgccgat gatctgatgc tggctgaaaa
    27541 caccgcggac gaagatgctg ccgaagccgc cgcgcaggtg ctttccagcg tggaatctga
    27601 aatcgggcgc acgactgacc cggtacgcat gtacatgcgt gaaatgggca ccgttgaact
    27661 gttgacccgc gaaggcgaaa ttgacatcgc taagcgtatt gaagacggga tcaaccaggt
    27721 tcaatgctcc gttgctgaat atccggaagc gatcacctat ctgctggaac agtacgatcg
    27781 tgttgaagca gaagaagcgc gtctgtccga tctgatcacc ggctttgttg acccgaacgc
    27841 agaagaagat ctggcaccta ccgccactca cgtcggttct gagctttccc aggaagatct
    27901 ggacgatgac gaagatgaag acgaagaaga tggtgacgac gataccgccg atgatgacaa
    27961 cagcatcgac ccggaactgg ctcgcgaaaa atttgcggaa ctgcgcgctc agtacattgt
    28021 aacgcgtgac accatcaaag cgaaaggccg cagtcacgct gccgctcagg aagagatcct
    28081 gaaactgtct gaagtattca aacagttccg cctggtgccg aagcagtttg actacctggt
    28141 caacagcatg cgcgtcatga tggaccgcgt tcgtacgcaa gaacgtctga tcatgaagct
    28201 ctgcgttgag cagtgcaaaa tgccgaagaa aaacttcatt accctgttta ccggcaacga
    28261 aaccagcgat acctggttca acgcggcaat tgcgatgaac aagccgtggt cggaaaaact
    28321 gcatgatgtc tctgaagaag tgcatcgcgc cctgcagaaa ctgcagcaga ttgaagaaga
    28381 aaccggcctg accatcgagc aggttaaaga tatcaaccgt cgtatgtcca tcggtgaagc
    28441 gaaagcccgc cgtgcgaaga aagagatggt tgaagcgaac ttacgtctgg ttatttctat
    28501 cgccaagaaa tacaccaacc gtggcttgca gttccttgac ctgattcagg aaggtaacat
    28561 cggcctgatg aaagcggttg ataaattcga ataccgccgt ggttacaagt tctccaccta
    28621 cgctacctgg tggatccgtc aggcgatcac ccgctctatc gcggatcagg cgcgcaccat
    28681 ccgtattccg gtgcatatga ttgagactat caacaagctc aaccgtattt ctcgccagat
    28741 gctgcaagag atgggccgtg aaccaacgcc ggaagaactg gctgaacgca tgctgatgcc
    28801 ggaagacaag atccgcaaag tgctgaagat cgccaaagag ccaatctcca tggaaacgcc
    28861 gatcggtgat gatgaagatt cgcatctggg ggatttcatc gaggatacca ccctcgagct
    28921 gccgctggat tctgcgacca ccgaaagcct gcgtgcggca acgcacgacg tgctggctgg
    28981 cctgaccgcg cgtgaagcga aagttctgcg tatgcgtttc ggtatcgata tgaacaccga
    29041 ccacacgctg gaagaagtgg gtaaacagtt cgacgttacc cgcgaacgta tccgtcagat
    29101 cgaagcgaag gcgctgcgca aactgcgtca cccgagccgt tctgaagtgc tgcgtagctt
    29161 cctggacgat taatcggtag gccggatcag gtgttacgcc gcacccggca ctagtccctc
    29221 cgcacaaacg ccaccttttc ggtggcgttt ttatcgccca cgcaccacca gcgcctggtc
    29281 cagctcgcga tacgcttcaa ccagtttctc cagtgaaacg cgacttaaac cgctgggatt
    29341 tggcagcacc caaatctgcg tcgaaccaat ggtgagcgtt tgtttccccc actgtgcacc
    29401 gcgctggctg aatccctgtt catatgcttg tttgcccaga atcgccaacg cctgcggctg
    29461 ataatcttca attttttcaa tcagcttacg cccgcctgcg tgtagctcct gctttgaaac
    29521 ttcattggct tgcaccgttg gacggtctac cagtttggtg acgccacaac gataatccag
    29581 cagatgctgt gcctcctgcg gcttcaactg acggtcggta aacccggcct gatatatcac
    29641 cttccagaag cgatttgccg gatgagcaaa gggaaaacca gtcccggcgg atgaaagacc
    29701 agggttgata ccgcaaaaca cgacccgtaa ccctggagcc aaaatatcct caaccatatt
    29761 tactcctttc taacatcacc aggaaaagta taacggattg aaaatacatt gtttataaaa
    29821 acagcaggcg cgcggtaatg gctggattgc gacacggagt tactttataa tccgctacca
    29881 tggcccctta gctcagtggt tagagcaggc gactcataat cgcttggtcg ctggttcaag
    29941 tccagcaggg gccaccagac atagcaaagg ctgacgagaa atcgtcagcc tttttctttt
    30001 tatatatccg ttactttgcg tgccagtaag ccgccgcacg tacccgctgt gggtcatact
    30061 gttccgtttc aaagcggcgg cttaaattct taacgacttt gccttcgccg gttatccaga
    30121 tgaagtaatc atcggcaggg atttgcatct gcgccagacg cgcatctacc gcctgctcat
    30181 catgtgccag ccattcgata ttaaaaccat caaggtgcgc gagataatcc tgacaggcgt
    30241 tatcccgcac gctaaccagc gcactaactt gcggtttaac agcaagtttg ctcaacgttt
    30301 ccaggcggcg gcgcagtgcg ggcattccgg attcatcgca gacatacagc tgatacgcgt
    30361 aatcttccgg caccaccagc gaaccgcgcg gacctgccac cgtaagttta tcgcccggtt
    30421 tcgcctgcat cgcccagccg ctggcgaccc caccgtcgtg aataaaaaaa tcaatcgcca
    30481 gttcatggcg tagttcgtca tacagcggcg tatagtcacg cgacggtggg cgtgatcctt
    30541 ccggccagac gatgccctct tccgttaccg ttggcggcac aaagtgagcg tcaggttgag
    30601 gaaagaagag tttgctgtga tcgtcaaagc cgcgcgatgt aaaaccgtcc agcgcctcgc
    30661 cgccgaggac aatgcgctga aaaccggcgc tgatgcgctc aacgcgtagc acagtcagtt
    30721 cacggaagcg cagatcattg cgaacgcgct gtgggtagcg gggggtgtta ttcattgtta
    30781 tcgccttcgt gatggtaatc agatatatct aaataaattc cacaaatgat aatgattgtt
    30841 aatcatgata aatgcaagtg atttgtagca ctgatatatc tgtagtctga taagacgcgc
    30901 aacctcttat caagcatcat tgctcaatgc cggatgcggc gtgaacgcct tatccggcct
    30961 acatgttgag taaacctgcg tttaaaaatc atttttgtac ttgcagtaat gctcatatca
    31021 gatataaatt agatatatct aattaagcaa aaggaggctg atatgagcca tcatcacgaa
    31081 gggtgttgta aacatgaagg ccagccacgc catgagggct gctgcaaagg tgagaagtca
    31141 gaacacgagc actgcggaca cggtcaccag catgaacacg gtcaatgctg cggtggtcgc
    31201 cacggtcgcg gcggcggtcg tcggcaacgt ttctttggtc acggtgaatt gcgtctggtg
    31261 attctggata ttctctcgcg cgatgacagc cacggttacg agttgattaa agcgattgaa
    31321 aatctgaccc aggggaatta caccccaagc ccgggcgtca tctacccgac gctggatttt
    31381 ctgcaggagc agtcgctgat taccatccgc gaagaggaag gtggtaagaa gcagattgcg
    31441 ctgaccgaac aaggcgcgca gtggctggaa gaaaaccgcg aacaggtaga gatgattgaa
    31501 gaacgcatca aagcgcgttg cgttggcgct gcgctgcgcc agaacccgca aatgaagcgg
    31561 gcgctggata attttaaagc ggtgctggat ttatgcgtca accagagcga tatcactgat
    31621 gcacaaataa aaaagatcat tgcggtgatc gaccgcgccg cttttgatat tacccaactg
    31681 gattaatcac cgattgccgg atgcggcgta ccctacacac cccgtaggcc tgataagatg
    31741 cgccagcatc gcatcaggca ttgtgctcca accgccggat ccggcatacc gattaatgca
    31801 gcaccgtcac cgcgtcttcc agtcggctgg cgcggtgttt caccatcgcc gacgcctgcg
    31861 cactctcttc cactaactcg gcgtttttct gggtgatcag gttaagctca tccactgcac
    31921 gggtcaggct ggaaagccca tcggcctgtt ccagcgttga atggctaatc tgagctatca
    31981 actgggtgac gttttttacc tgcgccacaa tatcttccat cgtccgtccg gcggcgtgta
    32041 cctgctgcga accagattgc accttatcag cactggcatc aatcagcttg cgaatatcgt
    32101 tggcagcatt ggcgctgcgg ctggctaaat gacgcacttc ccccgccacc actgcaaaac
    32161 ctttgccctg ttcgccggca cgcgccgctt ccaccgccgc attcagggcc agaatattgg
    32221 tctgaaacgc aatatcgtta atcagcgaag taatggtgcc aatgcgctgg gtactgtcgg
    32281 caatatcgtc cattgtcttg atcaccgtag tcatcgcctc cccgccctgc actgccgcat
    32341 tactggcggt gatagaaagt ttatcggcag ccgacgccgt ggcagagttc tgtttcaccg
    32401 acgccgccat ttggttcatg gtcgccaccg tttgctgaac gttatcaact gtctgctggg
    32461 tatgttcgtt cagttcatcg gtgcctttcg ccagcgtctc actgccgttt ctgacactgg
    32521 acacctggct tgagacatca ttaattagcc aacggcacat caggccaagc tgccctaccg
    32581 cgcgtaatgt cagccccagc tcatcgctgc gcttcagatg ctcaacacta ttacgttctc
    32641 cggtcgccac tttcagtgcc tggctggcga cattttctat cggacgtaca atttgccatt
    32701 caaaacaggc atttcccaac aacatcacta atgcacagaa gatatacgtc accaccgggg
    32761 cagcaacaaa ccagagcatg gccgccagca cgataaacat cagggtcatc actccacgcg
    32821 cccgccagcg aagcggtaat gaaggcagtt tacccagcca gcctttacgc accaccaggc
    32881 ctttatgaat acgcttaccg gtacgtccgg cattcagcgc tttgtacagc ggctccaccg
    32941 ccgcgatctc ttcatccgtc gcccgggtac gaatcgacat atagccactg atttttccct
    33001 cgcgcaccat cggtaccgca ttggcccgca cccaataatg gtcgccattt ttgcggcgat
    33061 ttttcacgat gccgctccag ggttcccctt ttttcagggt gaaccacata tccgcaaacg
    33121 ccgcttttgg catatccggg tgacgcacca tgttgtgcgg ttgcccctgt aactcctgca
    33181 aggtatagcc gctcacctgc acaaaagtgt cattagcatg agtgatatag ctttgcagat
    33241 cggtagtgga catcagagtg gtgtcgtccg ccagcggggt attttgctgg gtgacatacg
    33301 gatgagaaga catgttcgcg tcctgtgcag gttatatggt tgttaacttc ttgtcagagt
    33361 ttatgtcggc cccgctgcgg ttatctttaa ccaattaatt tgatttagat cgcaatttgc
    33421 gattaaagca caaatctaat tccttgattt aaaatacttt cactctgtta ctatacgaaa
    33481 acgttaatta tcttgcccaa aaatcaggca attattgccc tgaaagcgtg catttgcgca
    33541 gcaatcatca aatccatacc cgacaaaaac cgtgcaaaat aacagcaaat gttagcaaat
    33601 agcattaaat attgcgcaaa tgataaccac atttgtgttt atcccgattt tcgcgatcgc
    33661 agccggagtg gcgcaatccc tgcaatactt aaatcggtat catgtgatac gcgagcctcc
    33721 ggagcatatt ttgaacaggt taccttcgag cgcatcagct ttagcgtgca gcgcccacgc
    33781 cctgaatctc attgaaaagc gaacgttgga tcatgaggag atgaaagcac ttaaccggga
    33841 ggtgattgaa tacttcaaag agcatgtcaa tccggggttt ttagagtatc gcaaatctgt
    33901 taccgccggc ggggattacg gagccgtaga gtggcaagcg ggaggtttaa atacgcttgt
    33961 cgacacccag ggacaggagt ttatcgactg cctgggaggt tttggaattt tcaacgtggg
    34021 gcaccgtaat ccagttgtgg tttccgccgt acagaatcaa cttgcgaaac aaccgcttca
    34081 cagccaggag ctgcttgatc cgttacgggc gatgctggcg aaaacccttg cggcgctaac
    34141 gcccggtaaa ctgaaataca gcttcttctg taatagcggc accgaatccg ttgaagcggc
    34201 gctgaagctg gcgaaggctt atcagtcacc gcgcggcaag tttactttta ttgccaccag
    34261 cggcgcgttc cacggtaaat cacttggcgc gctgtcggcc acggcgaaat cgaccttccg
    34321 caaaccgttt atgccactgc tgccagggtt tcgtcatgta ccgtttggca atatcgaagc
    34381 catgcgcacg gctcttaacg agtgcaaaaa aaccggtgat gatgttgctg cggtgatcct
    34441 cgaaccgatt cagggcgaag gtggcgtaat tctgccgccg ccaggctatc tcaccgccgt
    34501 gcgtaagctg tgcgatgagt tcggcgcact gatgatcctc gatgaagtac aaacgggcat
    34561 ggggcgcacg ggcaagatgt tcgcctgcga gcatgagaac gtacagccgg atatcctttg
    34621 tctggcaaaa gcgctcggcg gcggcgtgat gccgattggc gcaaccatcg ccactgaaga
    34681 ggtgttctca gtcctgttcg acaatccgtt cctgcacact accacctttg gcggcaaccc
    34741 gctggcctgt gcggcggcgc tggcgaccat caatgtgttg ctggagcaga acttaccggc
    34801 tcaggctgaa caaaaaggcg atatgttgct ggacggtttc cgtcaactgg cgcgggaata
    34861 tcccgatctg gtacaggaag cgcgtggtaa agggatgttg atggcgattg agtttgttga
    34921 taacgaaatc ggctataact ttgccagcga gatgttccgc cagcgcgtac tggtggccgg
    34981 aacactcaac aacgctaaaa cgatccgcat tgaaccgcca ctgacactga ccattgaaca
    35041 gtgtgaactg gtgatcaaag cggcgcgtaa ggcgctggcg gccatgcgag tcagtgtcga
    35101 agaagcgtaa tatcaaatcg gatggcgata cgacgtcgcc atccgatctt tttatacgat
    35161 acgtacgccc gcaggcatca tccgctccgg cgttaacagc acgctttcac tgccgtcatc
    35221 ggtttccgca cacaacagca tgcattccga cgtttcaccg cgcattttcg ctttttgcag
    35281 attgcataag accaccactg tttttcccat cagctcttct tcgctgtagt acggcaccag
    35341 actggtcacg gtttgcagcg ttttttcccc cacatcaacc tgtacgatgt acagcttgtc
    35401 ggcgttttca tggcgtttca cttccacaat ctttccgacg cgcatttcca gacgtgcaaa
    35461 atcagcgtaa gccacggttt ccattgtttc ctcccttcaa gtaaaatttt actaaactat
    35521 agcaaaagtt tttctcaatc ctgtaggcta aaaatggaga atgcaggcgt gatcacattc
    35581 gtgagccgct gtgttaccgt cacagcgtca aagaaacgcg ctttatttac tgaaaacagg
    35641 tgacccgata agcacttcct ctacaatggg ggcgcacatc agggaaagta aaaaaggtaa
    35701 acatggcaac actaaaagac atcgcaatcg aagctggcgt atccctggcg acagtatcca
    35761 gggtcttgaa tgacgatccg acattgaatg tgaaagaaga gacgaaacat cgcattctcg
    35821 agatcgccga aaagctggag tacaagacca gtagcgcccg taaactccag acaggcgcag
    35881 tcaaccaaca ccatattctg gctatctaca gctaccaaca ggagttggag atcaacgatc
    35941 cttactatct ggcgatccgc cacggcattg aaactcagtg cgaaaagctg gcgatcgaac
    36001 tgaccaactg ttatgaacac aacggcttac cagacattaa aaacgtcacc ggtattttaa
    36061 ttgtcggcaa acccacgtcc gccctgcgcg ccgccgcctg tgcgttgacc gacaatatct
    36121 gttttatcga ctttcacgaa cccggcagcg gttacgatgc ggtggatatc gatctggcac
    36181 gtatcagtaa agaaatcatc gatttctata tcaatcaggg cgttaatcgt attggtttta
    36241 ttggcggtga agacttaccc ggcaaggcgg atattcgtga ggtcgccttt gcggaatatg
    36301 gtcgtctgaa acacgtggta cgcgaagagg atatctggcg cggcggtttt tccagttcgt
    36361 cgggctatga actggcaaaa cagatgctgg cgcgggaaga ctatccgaag gcactgtttg
    36421 ttgcttccga ttccattgct atcggcgtac tgcgggcaat tcatgaacgt ggcctgaaca
    36481 tcccacagga tatttcgctt atcagcgtta acgatatccc caccgcgcga tttacctttc
    36541 cgccgctctc caccgtgcgc atccattccg agatgatggg aagtcagggc gttaacctgg
    36601 tgtatgaaaa agcccgcgat ggtcgcgcgc tgccgctgtt ggtcttcgtt cccagcaaat
    36661 taaaactgcg cggcacgacc cgttaaatcc ccttacacac tgtccggcaa tcgtttttgc
    36721 cggacagtgc tgccgtttat tttcgtgatc cagttaaagt aaatgcattt acctgctatt
    36781 ttttagtaaa aattttacta aactccccag caattacaca aactaccatc accataaatg
    36841 gttccgattt ctctctaccg ggaggcccta tgaatcgctg ggaaaacatt cagctcaccc
    36901 acgaaaaccg acttgcgccg cgtgcgtact ttttttcata tgattctgtt gcgcaagcgc
    36961 gtacctttgc ccgcgaaacc agcagcctgt ttctgtcctt aagcggtcag tggaatttcc
    37021 acttttttga ccatccgctg caagtaccag aagccttcac ctctgagtta atggctgact
    37081 gggggcatat taccgtcccc gccatgtggc aaatggaagg tcacggcaaa ctgcaatata
    37141 ccgacgaagg ttttccgttc cccatcgatg tgccgtttgt ccccagcgat aacccaaccg
    37201 gtgcctatca acgtattttc accctcagcg acggctggca gggtaaacag acgctgatta
    37261 aatttgacgg cgtcgaaacc tattttgaag tctacgttaa cggtcagtat gtggggttca
    37321 gcaaaggcag tcgcctgacc gcagagtttg acatcagcgc gatggttaaa accggcgaca
    37381 acctgttgtg tgtgcgcgtg atgcaatggg cggactctac ctacgtggaa gaccaggata
    37441 tgtggtggtc ggcggggatc ttccgcgatg tttatctgat cggaaaacaa ctcacgcaca
    37501 ttaacgattt caccgtgcgc accgactttg acgaagccta ttgcgatgcc acactttcct
    37561 gcgaagtggt gctggaaaat ctcgccgcct cccctgtcgt cacgacgctg gaatataccc
    37621 tgtttgatgg cgaacgcgtg gtgcacagca gcgccattga tcatttggca attgaaaaac
    37681 tgaccagcgc ccgctttgat tttactgtcg aacagccgca gcaatggtca gcagaatccc
    37741 cttatcttta ccatctggtc atgacgctga aagacgccga cggcaacgtt ctggaagtgg
    37801 tgccacaacg cgttggcttc cgtgatatca aagtgcgcga cggtctgttc tggatcaata
    37861 accgttatgt gatgctgcac ggcgtcaacc gtcacgacaa cgatcatcgc aaaggccgcg
    37921 ccgttggaat ggatcgcgtc gagaaagatc tccagttgat gaagcagcac aacatcaact
    37981 ccgtgcgtac cgctcactac ccgaacgatc cgcgttttta cgaactgtgt gatatctacg
    38041 gcctgtttgt gatggcggaa accgacgtcg aatcgcacgg ctttgctaat gtcggcgata
    38101 tcagccgtat taccgacgat ccgcagtggg aaaacgtcta cgtcgagcgc attgttcgcc
    38161 atattcacgc gcagaaaaac catccgtcga tcatcatctg gtcgctgggc aatgaatccg
    38221 gctatggctg taacatccgc gcgatgtacc atgcggctaa ggcgctggat gacacgcgac
    38281 tggtgcacta cgaagaagat cgcgatgctg aagtggtcga tattatttcc accatgtaca
    38341 cccgcgtgcc gctgatgaat gagtttggtg aatacccgca tccgaagccg cgcatcatct
    38401 gtgaatatgc tcatgcgatg gggaacggac cgggcgggct gacggagtac cagaacgtct
    38461 tctataagca cgattgcatt cagggacatt atgtctggga atggtgcgac cacgggatcc
    38521 aggcgcagga tgacaacggc aatgtctggt ataaattcgg cggcgactac ggcgactatc
    38581 ccaacaacta taacttctgt cttgatggtt tgatctattc cgatcagacg cctgggccgg
    38641 gcctgaaaga gtacaaacag gttatcgcgc cggtaaaaat ccacgcgttg gatctgactc
    38701 gcggcgagtt gaaagtcgaa aataaactgt ggtttaccac gctggatgac tacaccctgc
    38761 acgcagaggt gcgcgccgaa ggtgaaacgc tcgcgacgca gcagattaaa ctgtgcgacg
    38821 ttgcaccgaa cagcgaagcc cccttgcaga tcacgctgcc gcaactggac gctcgtgaag
    38881 cgtttctcaa cattacggtg accaaagatt cccgcacccg ctacagcgaa gccggacacc
    38941 ctatcgctac ttatcagttc ccgctgaagg aaaataccgc gcagcctgta cctttcgcgc
    39001 caaataatgc gcgtccgctg acgctggaag acgatcgttt gagctgcacc gttcgcggct
    39061 acaacttcgc aatcaccttc tcaaaaatga gtggcaaacc gacatcctgg caggtgaatg
    39121 gcgagtcgct gctgacccgc gagccaaaga tcaacttctt caagccaatg atcgacaacc
    39181 acaagcagga gtacgaaggg ctgtggcagc cgaatcattt gcagatcatg caggaacatc
    39241 tgcgcgactt tgccgtagaa cagagcgatg gtgaagtgtt gatcatcagc cgcacggtta
    39301 ttgccccacc ggtgtttgac ttcgggatgc gctgcaccta catctggcgc atcgctgccg
    39361 atggccaggt taacgtggcg ctttccggcg agcgttacgg cgactatccg cacatcattc
    39421 cgtgcatcgg tttcaccatg gggattaacg gcgaatacga tcaggtggcg tattacggtc
    39481 gtggaccggg cgaaaactac gccgacagcc agcaggctaa catcatcgat atctggcgca
    39541 gcaccgtcga tgccatgttc gagaactatc ccttcccaca gaacaacggc aaccgtcagc
    39601 atgtccgctg gacggcactg actaaccgcc acggcaatgg tctgctggtt gttccgcagc
    39661 gcccaattaa cttcagtgcc tggcactaca cccaggaaaa catccacgca gcccagcact
    39721 gtaacgagct gcagcgcagt gatgacatca ccctgaatct cgaccaccag ttgcctggcc
    39781 tcggctccaa ctcctggggc agcgaggtgc tggactcctg gcgcgtctgg ttccgtgact
    39841 tcagctacgg ctttacgttg ctgccggttt ctggcggaga agctaccgcg caaagccagg
    39901 cgtcgtatga gttcggcgca gggttctttt ccacgaattt gcacagcgag aataagcaat
    39961 gaggatcatc gataacttag aacagttccg ccagatttac gcctctggca agaagtggca
    40021 acgctgcgtt gaagcgattg aaaatatcga caacattcag cctggcgtcg cccactccat
    40081 cggtgactca ttgacttacc gcgtggagac ggactccgcg accgatgcgc tatttaccgg
    40141 gcatcgacgc tattttgaag tgcattacta cctgcaaggg cagcaaaaaa ttgaatatgc
    40201 gccgaaagag acattacagg tagtggaata ttatcgtgat gaaactgacc gcgaatattt
    40261 aaaaggctgc ggagaaaccg tagaggtcca cgaagggcaa atcgttattt gcgatatcca
    40321 tgaagcgtat cggtttatct gcaataacgc ggtcaaaaaa gtggttctca aagtcaccat
    40381 cgaagatggt tatttccata acaaataaaa actacggcgg caaaaggagt ttgccgccac
    40441 cgctacccta ctcattttcg gagatgtgtt atgtctgata ccaaacgtaa tacaatcggc
    40501 aaattcggct tgctctcgct gacttttgcc gccgtttaca gctttaacaa cgttatcaat
    40561 aataatattg agcttggact ggcctcggca ccgatgtttt tcctcgcaac aattttttat
    40621 tttattccct tctgtctgat catcgcagaa tttgtttcgt taaataaaaa ctcggaagcc
    40681 ggtgtctacg cgtgggtaaa aagttcgctg ggcggacgtt gggcatttat tactgcctat
    40741 acctactggt tcgtaaacct gttctttttc acctcattat tgccgcgcgt tattgcttac
    40801 gcctcgtatg cattcctcgg ctacgaatat attatgacgc cggttgccac caccattatc
    40861 agtatggtgc tgttcgcctt ttccacctgg gtttctacca acggggcgaa aatgctgggg
    40921 ccaattacct ccgtcacttc aacgctgatg ctgctgttaa cgctctccta cattttactg
    40981 gcaggtacgg cactggttgg cggcgtacag cctgctgacc ccatcactgt tgacgcgatg
    41041 atcccaaact ttaactgggc gttcctcggc gttaccacct ggatctttat ggctgcaggt
    41101 ggcgcggagt ccgtcgcggt gtacgttaac gacgtcaaag gcggttcgaa atcgttcgtt
    41161 aaagtgatca tcctcgccgg gatttttatt ggcgtactgt actccgtctc ctcggtactg
    41221 attaacgtct tcgtcagcag caaagagttg aagtttaccg gcggatcggt acaggtattc
    41281 cacggcatgg cggcgtattt tggtctaccg gaagcactga tgaatcgctt tgtcggtctg
    41341 gtgtccttta ccgcgatgtt cggttccctg ctgatgtgga cggcaacgcc ggtgaaaatt
    41401 ttcttctccg aaattccgga aggcatcttt ggtaagaaaa ccgtcgaact gaacgaaaac
    41461 ggcgttccgg cgcgcgcagc gtggatccag ttcctgatcg tcatcccgct gatgattatc
    41521 ccgatgctcg gttccaatac cgtgcaggat ctgatgaata ctattattaa tatgactgct
    41581 gcagcgtcca tgcttccgcc gttattcatc atgctggctt acctgaattt acgcgccaaa
    41641 ttagatcacc tgccacgcga tttccgtatg ggctcccgcc gcaccggtat tatcgttgtt
    41701 tcaatgctga ttgcgatatt tgcagtaggg tttgtcgctt cgacattccc gactggcgcg
    41761 aatattctga ccatcatttt ttataacgtc ggcggtattg ttatcttcct cggctttgcg
    41821 tggtggaaat acagtaaata tataaaggga ttaacggctg aagagcgcca tattgaagcg
    41881 acgccagcca gcaatgttga ttaagcagaa taataaaaaa tgagcaggca ttttccctct
    41941 tcctggatgg ggagagggaa aatagtttct gcctttatat ttttataatt acaacgataa
    42001 aaggctgtac tttttcttta gctcatggat taacacaatg aaattaatca ctgcaccatg
    42061 cagagcatta cttgccctgc ctttttgcta cgctttttct gcacttggcg aagaagcacg
    42121 tccggcagaa catgacgaca caaaaacccc cgaaatgatc tcgacatctt ctccttcatt
    42181 tcgtttttac ggcgaattag gggttggtgg gtatatggat ttagagggtg agaataaaca
    42241 taaatacagc gacggcacct atattgaagg tggcctggag atgaagtacg actcctggtt
    42301 cggcctgatt tacggcgaag gctggaccgt gcaggccgac cacgacggta atgcctgggt
    42361 gcctgaccat agctggggtg gtttcgaagg tgggattaac cgtttctatg gcggttatcg
    42421 taccaatgat ggcaccgaaa tcatgctcag tctgcgtcag gattcctcgc tggatgacct
    42481 gcaatggtgg ggcgatttca cgcccgatct gggctacgtc attcccaata cccgcgacat
    42541 tatgactgcg ctgaaggtac agaacttaag cggcaacttt cgttatagcg ttaccgccac
    42601 acctgccgga catcatgacg aaagcaaagc ctggctacat tttggcaagt acgatcgcta
    42661 cgacgacaaa tacacctatc cggcaatgat gaacggttac atccagtatg accttgcaga
    42721 aggtatcacc tggatgaacg gtctggaaat caccgacggc acaggccaac tctatctcac
    42781 gggcctgctt acccctaact ttgccgctcg cgcctggcac cataccggac gcgccgacgg
    42841 gctggacgta ccgggaagtg aaagtgggat gatggtgagc gccatgtatg aagcgttaaa
    42901 gggcgtttat ctctccaccg cttacaccta cgccaaacat cgccctgacc acgctgacga
    42961 tgaaaccacc tctttcatgc agtttggtat ctggtacgaa tacggcggcg gacgtttcgc
    43021 aacggctttt gatagccgct tctacatgaa aaatgcctct cacgatccca gcgaccaact
    43081 cttcctgatg caatattttt actggtaata aggacagtaa tctcatgaaa atcaaaacta
    43141 ttttaacacc agtagcctgt gctctgctga tgagcttttc cgcccatgcc gctaacgctg
    43201 acaattataa aaacgtgatt aaccgtactg gcgcgccgca gtacatgaag gattacgatt
    43261 acgacgatca ccagcgtttt aatccgtttt tcgatctcgg agcctggcat ggtcatctgt
    43321 tgccagacgg cccgaacact atgggcggct ttccaggcgt tgcgttgttg acggaagagt
    43381 acatcaactt tatggccagc aatttcgacc gcctgaccgt ctggcaggac ggcaagaaag
    43441 tcgatttcac gctggaggca tacagtattc ccggcgcgct ggtgcaaaag ttgatatcga
    43501 aagatgtaca ggtcgaaatg attctgcgct tcgccacgcc gcgcacatca ctactggaaa
    43561 ccaaaatcac cagcgataaa ccgctggatc tggtgtggga tggcgaactg ctggaaaaac
    43621 tggaagcgaa agaagggaaa ccgctttccg ataaaaccat tgctggcgag taccctgact
    43681 atcagcgcaa aatcagcgcc acccgcgatg gcctgaaagt tacctttggc aaagtgcgcg
    43741 ccacctggga tctgctgacc tccggtgaat cagaatatca ggtgcataaa tcattaccga
    43801 tgcagactga aatcaacggc aatcgcttta ccagtaaggc gcatatcaac ggatcgacga
    43861 cgctctatac cacctattcc catctgctga ccgctcagga agttagcaaa gagcaaatgc
    43921 agatccgcga tattctggcg cgtccggcgt tttatctcac cgcctcgcag caacgttggg
    43981 aagaatacct gaagaaagga ttaaccaatc cggatgcgac gccggaacag acgcgcgtcg
    44041 cggtgaaagc catcgaaacg ctcaacggta actggcgatc gccgggcggt gcggtgaaat
    44101 ataacaccgt cacgccgtcg gtgaccgggc gctggttctc cggcaaccag acctggccgt
    44161 gggatacctg gaagcaggcg tttgcgatgg cgcatttcaa tccggacatc gccaaagaga
    44221 atatccgcgc ggtcttctcc tggcagatcc agccaggcga ccgcgtgcgt ccgcaggatg
    44281 tgggctttgt ccccgacctg atagcgtgga accttagccc cgagcgtggc ggcgatggcg
    44341 gcaactggaa cgaacgtaat accaaaccca gccttgccgc ctggtcagta atggaagtgt
    44401 ataacgtcac ccaggataag gcctggttgg cagagatgta cccgaagctg gtggcctatc
    44461 acgactggtg gttacgtaac cgcgatcaca acggcaacgg cgtgccggaa tatggcgcga
    44521 cccgcgacaa agcccacaac accgagagcg gcgagatgct gtttacggtg aaaaaaggcg
    44581 acaaagagga gacgcagtct gggctgaaca actacgcccg tgtggtggag aaaggccagt
    44641 acgacagtct ggaaattccg gcacaggttg ctgcgtcgtg ggaatcaggt cgtgatgacg
    44701 ccgccgtttt cgggtttatc gacaaagaac agctggataa atatgtcgct aacggcggca
    44761 aacgtagcga ctggacggtg aaattcgccg aaaaccgcag tcaggacgga acgttgctgg
    44821 gctactcgct attgcaggag tcggtggatc aggccagcta tatgtacagc gataaccatt
    44881 atctggcgga gatggcgacg attctcggta agccggaaga ggccaaacgc tatcgtcagt
    44941 tagcacaaca gctcgcggac tacatcaaca cttgtatgtt cgacccgact acacagttct
    45001 actatgacgt gcgtattgaa gataaaccgc tggcgaacgg ctgcgcgggc aaaccgatta
    45061 ttgagcgcgg taaagggccg gaaagctggt cgccgctgtt taacggtgag gcaacgcagg
    45121 ccaatgccga cgcggtggtg aaggtgatgc tggatccgaa agaattcaac acctttgtcc
    45181 cgctgggaac ggcggcgtta accaatccgg cttttggcgc ggatatctac tggcgcgggc
    45241 gcgtatgggt ggatcagttc tggtttggtc tgaaagggat ggagcgttac ggttatcgtg
    45301 atgatgccct gaagctggcg gatacgttct tccggcacgc caaaggatta accgccgatg
    45361 gcccaattca ggagaattac aacccgctca ctggctcgca acaaggcgca ccaaatttct
    45421 cctggagtgc cgcgcatttg tatatgttgt ataacgattt tttccgtaag cagtaatttg
    45481 caacggctgg cggatgcggc gtgaacgcct tatccgccct acatgtgcaa tcccccaggc
    45541 cggataaaac gcggcaagcg tcgcatccgg cgttaccacc gggcgtattc tttttgaatc
    45601 ccatcacaaa ccccgcactc cccttttccc ttttctccgg cgacggctaa attagaactc
    45661 atccgaccac ataacaatta ttttacatac tggacaattt tatgagctac ccgtcgctgt
    45721 tcgccccgct ggatttaggt tttaccacgt taaaaaaccg cgtgttgatg ggctcaatgc
    45781 acaccgggct ggaggagtac ccggacggcg ctgaacggct ggcagcgttt tatgccgaac
    45841 gcgcccgtca cggcgtggcg ttgattgtca gcggcggtat cgcaccagat ttaacaggcg
    45901 ttggcatgga aggcggtgca atgctcaatg acgccaacca gatcccacac catcgcacca
    45961 ttaccgaagc cgtacatcag gaaggcggca aaatcgccct gcaaattttg cataccgggc
    46021 gctacagcta ccaaccgcat ctggtcgctc cctccgcatt gcaggccccc atcaaccgtt
    46081 tcgttcctca cgaactcacc catgaagaga tcctgcaact gatcgacgat ttcgcccact
    46141 gcgcgcaatt ggcacgggag gcaggatacg acggtgtaga ggtgatgggg tccgaagggt
    46201 atttgatcaa cgaatttctg acgctgcgca ccaatcagcg tagtgaccag tggggcggcg
    46261 attaccgcaa ccggatgcgg tttgccgtag aagtagtgcg tgcggtgcgc gaacgtgtcg
    46321 gcaacgactt cattattatc taccgtttgt cgatgctcga cctggtcgaa ggcggcggta
    46381 cttttgccga aatggtagag ctggcgcagg ccattgaagc ggcgggcgcg accattatca
    46441 acaccggcat tggctggcat gaagcgcgga ttccgaccat cgccacgccc gtgccgcgcg
    46501 gcgcctttag ctgggtcacg cgcaaactga aagggcacgt ttcgctgcca ctggtgacca
    46561 ccaaccggat taacgatccg caggttgccg acgacattct ctcgcgcggt gatgcggaca
    46621 tggtatcgat ggcgcgaccg tttctcgctg atgcggagct gctatcaaaa gcgcaatcgg
    46681 gacgagccga tgagatcaac acttgtattg gctgcaacca ggcctgtctc gatcagatct
    46741 tcgttggcaa agtcacctcg tgcctggtga atcctcgcgc ctgccacgaa accaaaatgc
    46801 caatccttcc tgccgtgcag aaaaaaaatc tggcggtggt cggtgcggga cctgctgggc
    46861 tggcgtttgc cattaacgcg gcggcgcgtg ggcatcaggt aacattgttt gatgcgcaca
    46921 gcgagatcgg cgggcagttt aatatcgcca aacagatccc cggcaaagag gagttttacg
    46981 aaacgctgcg ctattaccgc cggatgatcg aagtgacggg tgtaacgcta aaactcaatc
    47041 acaccgtgac ggcggatcag ttacaggcgt tcgatgaaac gatcctcgcc agtgggatcg
    47101 tgccgcgcgt tccgcctatc gacgggatcg atcatccgaa ggtactgagt tatctcgatg
    47161 tactgcgcga caaagcgccg gtgggcaaca aagttgccat catcggttgt ggcggaattg
    47221 gttttgatac ggcgatgtat ttaagtcagc cgggcgaatc caccagccag aatatcgccg
    47281 ggttctgtaa tgagtgggga atcgacagta gcctgcaaca ggccggaggt ttgagtccgc
    47341 aaggcatgca aatcccccgt agcccacggc agattgtgat gctccagcgc aaagccagca
    47401 aaccaggaca agggttaggc aaaaccaccg gctggatcca tcgcaccacc ctgctctcac
    47461 gcggcgtgaa aatgatccca ggcgtaagtt accagaagat cgacgatgac gggctgcatg
    47521 tagtgatcaa cggcgaaacg caggtactag cagtggacaa tgtggtgatc tgcgcggggc
    47581 aagagccaaa ccgcgcattg gcgcaaccgc tgattgatag tgggaaaact gtgcatttaa
    47641 ttggcggctg cgatgtagct atggagctgg acgcacggcg ggcaattgcc cagggaacac
    47701 ggctggcgct ggagatttaa atcgttgttt gaagcgccgg atgcgacgca tccggcacgt
    47761 cgcgttaatc aataaacaag gcgggagaaa taccgaatcg cgttgccagt tttttagcgt
    47821 gttccagcgt taatttcctt ttcccgctca aaacgcgtga caccatcgat ttactgccta
    47881 tttccggaag atcggaaagg gttaaaccat attgatccat aagggtacga atcacggcta
    47941 taccgccagg catggcttga gccatggcat taaattccac aaattcgggc gctgattctt
    48001 cccacgcggt tattttggca cacaccagat ccagtaaggg gttttcagga tcgttgagca
    48061 gcagatgatc taccagttcc agcgcctggg tgtattgttc ctcgttctga atacccgcca
    48121 gaaaaggtgc cacagcagtt agcttttctc ctgcttgcaa gatgtcggca atcgcaatca
    48181 ttttttcccc ttagtacgat gaacggcggt aaagaaatcg tattctttat gcgtcataac
    48241 ttcacgtatg tagcactttt gcgattcaaa aaagaccatt gctacaacac gtaattcatt
    48301 gcccccgaca ttgaaaacat aatgcttatc cagatatttg aagttatcca gagaagggaa
    48361 tactgctttt aatgactcag gttttttgaa atatccctta gcaatcgtgt tccccagagc
    48421 caccaactcc gttttatgtt gcgggtattt ttccgcagca tctttcaatg ctttttgagt
    48481 tatcaggtgc attcttcatc acgtccgttg acaaattggc aatatgataa catccgttga
    48541 cagattggca acgaatgaat ttatctgtgt gacggaagaa taaacgtaga aaaacgctaa
    48601 acaagagaat gtagaggatg gtgacaggaa ttttttgttt tatggaagcg cgattccaga
    48661 actgggcaga cattgccgga tgcgacgctt gccgcgtctt atccgacctg ggggtaatgt
    48721 gctgaacgta tgccggataa ggcgtttacg ccgcatccgg caggtaaccc tcaatcttac
    48781 cgacgacgcc ccagcttcac tgctttcagc accacaaatt tattattcgt ggcgatggtg
    48841 gtgcagttgc cgaaaatttt cttcagttta tggaagtaat ccaagtgacg gttggcaacg
    48901 atatacagct cgccgttgat tttcaggcag cggcgggcgt ggtggaacat ctcccaggcg
    48961 acgttatcgg tcagcgcatg ttgctgatga aacggcgggt tgcagagcac agcattaaaa
    49021 cggaaaggct ccacgccgga aagcgcgttg ttgatcataa actcgcagcg atccagtgcc
    49081 tcgggcatgt tggtttcaac gttcaaacgg ctggaagcaa ccgccatcgg tgattcatcg
    49141 acaaacacca ctttcgcctg cgggttttta tcgagcaatg tcaggccaat aacgccatta
    49201 ccgcaaccga gatcgacaat ctcaccttcg agattctctg gcagatgttg cataaagaag
    49261 cgcgcgccaa tatccagccc ggtgcgggag aagacattcg catggttgtg gatagtccag
    49321 tcagtacctt ccagcttcca gctaacggtc tgcggcgcat cggccaacgg cggttcgttg
    49381 aaggtgcagt taatcaggcg cgctttcttc catgccagcg tggtggtggt cgggccgagc
    49441 actttttcga acaattccag cgtggaagtg tgaatgtcac gggctttggc accagcaata
    49501 atgcgcgtat ctggcgtgac cactttgcgc agcgcgcgca gttgttgttc cagcaatgcc
    49561 agtgttttcg gcactttgat cagcaccaca cccggctgtt gcgggtagtc ggcggtgctg
    49621 tcgagaaact tcacgctcga ctcatcaatc ccgttgaggc gtaaattctc gcgcgtggcc
    49681 agttcactga tgtatgagtc gccaatgctg tacggcttat gttccgccag cacacagctt
    49741 aacgcaccaa aagcatcatt caggatcaac accgggccgc ggatttctgt gtcgtccaac
    49801 tgttgcagca aatactcatc cgccgcttcc cacgcctgta gcgggttaac gtcatccgtc
    49861 gccggaaaac gttgtagtgt cagtgaacgg aaaccgttgt ctaagtggct catcggccct
    49921 cctgaatgat aaaatttcga cgttgcccct gaaaagggtg cgtgagtata ccctttttct
    49981 ctttttcgtg ggcggttatg agcaatctta cttatcttca gggttatccc gagcagctac
    50041 tttcccaggt gcgaacgctg attaacgaac agcgtctggg cgatgtgctg gcaaaacgtt
    50101 atccgggaac acacgactac gccaccgata aagccctctg gcaatatact caggatctta
    50161 aaaatcagtt tctgcgcaat gccccgccga tcaataaagt gatgtatgac aataagatcc
    50221 acgtgctgaa aaacgcgctc gggttacata ctgccgtttc gcgtgtgcag ggcggcaagc
    50281 tgaaagcaaa agcagagatc cgcgtcgcta ccgtgtttcg caacgcgccg gaaccgtttt
    50341 tgcgcatgat cgtggtgcac gagctggcgc acctgaagga gaaagagcat aacaaagcgt
    50401 tttaccagtt gtgctgtcat atggaaccgc agtaccacca gcttgagttc gacacccggc
    50461 tgtggctaac gcagttgtcg cttgggcagg acaaaatctg aaaatgatgt caggcgttat
    50521 tttttcctcc tttagcgcct aaaatcgatc tcctcccttt cgttaaggat aacgaccatg
    50581 ctgcgcgcat ttgcccgcct tcttcttcgt atttgttttt ctcgccggac tcttaaaatt
    50641 ggctgtttat tgttgcttat agcaggagcg accattttta ttgccgatcg cgttatggtc
    50701 aacgccagca agcagctgac ctggagtgat gtcaacgccg ttccggcgcg gaacgtgggt
    50761 ttattgctgg gggcgaggcc gggtaatcgc tactttaccc gacgtattga tagcgccgca
    50821 gagttgtacc acgccggaaa agtgaaatgg ctattggtga gcggcgataa tggacgtaaa
    50881 aattacgatg aagcgtcagg aatgcagcaa gccttgatcg ctaaaggcgt accggcaaaa
    50941 gccatcttct gcgactatgc cggattctca acgcttgatt cggtggtgcg tgccaacaag
    51001 gtgtttagtg aaaaccatat caccattatc tcgcaagaat ttcataacca acgcgccatc
    51061 tggctggcaa aacagtatgg tatcgatgct atcggtttta acgcgccaga cctgaatatg
    51121 aagcacggtt tatatactca actgcgggaa aaacttgcca gagtcagcgc ggtgattgat
    51181 gcgaaaatcc tccatcgcca gccgaaatat ctcgggccgt tggttatgat tgggccgttt
    51241 agtgagcatg gctgtccggc aaaagaataa tgcgtatctg cgcacgtcga agataaaaaa
    51301 ggcgtgctac agtgacgaca gaatcccttt atggagtatc cacgcgttat gatacgtttc
    51361 gctgtgattg gtacgaactg gatcactcgc cagttcgtcg aggccgccca tgagagcggt
    51421 aaatacaagt taaccgccgt ctattcccgc agccttgaac aggcccagca cttcgccaat
    51481 gatttttctg tcgagcatct gtttacgtcg ctggaagcga tggcagaaag cgatgccatt
    51541 gacgcggtgt atattgccag cccaaattcc ctgcactttt cccagacaca acttttcctt
    51601 agtcacaaaa ttcatgtgat ttgcgagaag ccactggcgt cgaatcaggc ggaagtggat
    51661 gccgccattg cctgtgcgcg ggaaaatcag gtggtgctgt ttgaggcatt taaaacggcc
    51721 tacctgccga actttcatct gttacgccag gcgctgccga aagtcggcaa actgcgtaaa
    51781 gtctttttca actattgcca gtattcctcg cggtatcagc gttacctgga cggagagaat
    51841 cccaacacct tcaatccggc attctccaac ggttcgatta tggatatcgg cttttactgc
    51901 ctggcgtcgg cggtggcatt attcggtgaa ccgaaaagcg tgcaggcaac cgccagtttg
    51961 ctggcaagcg gtgtggatgc ccacggcgtg gtggtgatgg attacggtga tttcagcgtt
    52021 acgttgcagc actcaaaagt gagcgattct gtcctggcaa gcgagattca gggcgaagcg
    52081 ggatcgctgg tgattgaaaa actctctgaa tgccagaaag tctgctttgt accgcgtggc
    52141 agccagatgc aggatctcac ccagccacag catattaata ccatgctcta cgaagcagag
    52201 ctgttcgcta ccctggtgga tgagcatctg gtgaatcatc cagggctggc ggtcagtcgt
    52261 atcaccgcca aactgctgac tgagatccgc cgccagactg gggtgatttt tccggcagat
    52321 aacgtaaaac tataattgcc aaagtaaaac agtgtaaaag gtatgtaaca gaccattgac
    52381 tgactgaatg gtctgtcata ctttgttacc tgcaaagggg agtaacttca ttgtcggtcg
    52441 atcgtcatta cggtgtgtga aaaaccacat ccggtcaccg ggcaacccga aaggaatacg
    52501 cagacgtatt ccttttttgt tgtaagtgag accttgccgg aaggcgaggt ctatgcataa
    52561 aaagcagcgg ctgacgtctt ccgacgttgg ccgttttttt atgtgtaagg aacttctatg
    52621 aatactgtcg gcacgccgtt gctatggggc ggattcgctg ttgttgtcac cattatgctg
    52681 gctatcgacc tgttgttgca ggggcgtcgt ggggcacatg ccatgaccat gaaacaggct
    52741 gcggcctggt cgctggtctg ggtgacgctg tcgttactgt ttaacgccgc tttctggtgg
    52801 tatctggtgc aaaccgaagg tcgcgccgtt gccgatccac aggcactggc ctttctcacg
    52861 ggttatctga ttgagaaatc gctggcggtc gataacgtct ttgtctggct gatgttgttc
    52921 agctatttct ctgttccggc ggcattacaa cgccgcgtgc tggtgtatgg cgtactcggg
    52981 gcgattgttc tgcgtaccat catgatcttc actggtagct ggctgatttc acagttcgac
    53041 tggatcttgt atatcttcgg tgccttcctg ctgtttaccg gcgtgaagat ggcgctcgcc
    53101 catgaagatg aatcaggcat tggcgacaag ccgctggtgc gctggctgcg cggtcatttg
    53161 cgcatgaccg acaccatcga caacgagcat ttctttgtgc gtaagaatgg tttgttgtat
    53221 gccacgccgc tgatgctggt gctgattctg gtggagttga gcgacgtgat tttcgccgtg
    53281 gatagtattc cggctatctt cgccgtgacc accgatccgt ttattgtgct gacctcaaac
    53341 ctgtttgcga tcctcggcct gcgtgcgatg tatttcctgc tggcaggtgt ggcagagcgt
    53401 ttctcgatgc tcaaatatgg tctggcggtg attctggtgt ttatcggtat caagatgctg
    53461 attgtcgact tctaccatat tccgatcgcc gtctcgctgg gcgtggtgtt tggcattctg
    53521 gtgatgacgt ttattatcaa cgcctgggtg aattatcggc atgataagca gcgggttgga
    53581 tgatttttaa tctgcctaag ccgtgtaccc tgtcatccac atgagcaccg ttttctccct
    53641 ctccccaaaa ggggcgaggg gactgaccga gtactttttt gacgttgtca tcagtctgga
    53701 agccgcacgt tgggctttat tttcatgtca aacaaatgta accattaagt tgcgaaatat
    53761 gacttctcct taaaatccag catatttcgc ttcccgaagc tgtaactttc cttatactcg
    53821 accttgcaaa cactttgtta catcctgaaa gatgcgtcga cagaacgcac cagggatgtg
    53881 cgacaacaca atgaaaggat cgaaaaatga ctacgcaaca ttcaccgggg ctattccggc
    53941 gtctggctca tggcagcctg gtaaaacaaa tcctggtcgg ccttatactg gggattcttc
    54001 tggcatggat ctcaaaaccc gcggcggaag ctgttggtct gttaggtact ttgttcgtcg
    54061 gcgcactgaa agccgttgcc cccatcctgg tgttgatgct ggtaatggca tctattgcta
    54121 accaccagca cgggcagaaa accaatatcc gccctatttt gttcctctat ctgctgggca
    54181 ccttctctgc tgctctggcc gcagtaatct tcagttttgc cttcccttct accctgcact
    54241 tgtccagtag cgcgggtgat atttcgccgc cgtcaggcat tgtagaagtg atgcgcgggc
    54301 tggttatgag catggtttcc aaccccattg atgcgctgct gaaaggtaac tacatcggga
    54361 tcctggtgtg ggcaattggc ctcggtttcg cactgcgtca cggtaacgaa accaccaaaa
    54421 acctggtcaa cgatatgtcg aatgccgtca cctttatggt gaaactggtg attcgcttcg
    54481 caccgatcgg tatttttggt ctggtttctt ctaccctggc aaccaccggt ttctccacgc
    54541 tgtggggcta cgcgcaactg ctggtcgtgt tggttggctg tatgttactg gtggcgctgg
    54601 tggttaaccc cttgctggtg tggtggaaaa ttcgtcgtaa cccgttcccg ctggtgctgc
    54661 tgtgcctgcg cgaaagcggc gtgtatgcct tcttcacccg cagctctgcg gcgaacattc
    54721 cggtgaatat ggcgctgtgt gaaaagctga atctggatcg cgatacctat tccgtttcta
    54781 ttccgctggg agccaccatc aatatggcgg gcgcagcaat caccattacc gtgttgacgc
    54841 tggctgcagt taatacgctg ggtattccgg ttgatctgcc cacagcgctg ctgttgagcg
    54901 tagtggcttc tctgtgtgcc tgtggcgcat ccggcgtggc ggggggatct ctgttgctga
    54961 tcccactggc ctgtaatatg ttcggtattt cgaacgatat cgccatgcag gtggttgctg
    55021 tcggctttat tatcggcgta ttgcaggact cctgtgaaac cgcgctgaac tcgtcaactg
    55081 acgtgctgtt cactgcggca gcttgccagg cggaagacga tcgtctggca aatagcgccc
    55141 tgcgtaacta atacttagcc cctttcgtct acggcggaag gggttttctc cactttaaac
    55201 ggatcaattc cccttctctg catacgccag aaacgaatga tattcaggcc attcatcagc
    55261 agaaaactgc cttcaatcat cgtgccgcct atcgaccccg cccagaagtt gtgaatcacc
    55321 cagcaacacg ttgaaaacca cattacgcag cgcatggtca gccctttaca gcggaacagc
    55381 gcccaggtac tgacaatcgt gccgattacc ggcaatagtt caacaggatg atggaacttc
    55441 gcgaggccaa ttccgccagt cagcacaata aaaatcgcca ttacccataa gctgcgcgtg
    55501 cgtaaggtaa tcaatgtacg aatggcatta aggatggcac tggcaccggc aggataggtg
    55561 cccagaagaa aaaaatgtac gccaataacg gcgctataga ccgaaagttg ctttttgaag
    55621 cgacgttcgt cacgattgaa aaatgttgtg ataccaatca gaaaggcgat gacacccacg
    55681 ccctgggcca gccaatacgc ggtcatgata aatccttagc aggtatggaa aagcaaacgg
    55741 cgcttcacat tatgaaacgc cgttttttat taacaactca tttcgacttt atagcgttac
    55801 gccgctttta aagatcgcca gttcgcggaa gtcgttacgc tcgttacagg tttgcttacc
    55861 gttggcaaac tcaacgatgg tgtcgataaa ttcttccagc aactgcggca tcgctttacc
    55921 gtggatcagc tgacccgcgt caaagtcgat ccagtgtttt ttcttcgccg ccagttcact
    55981 gttggtggcg attttcaccg tcggcacaaa tccaccatac ggcgtgccac gaccagtact
    56041 gaacagcacc atatggcagc ccgcacccgc cagggcgctg gtcgctacgg catcgttacc
    56101 cggcgcactt aacaagttca gccccggcgt tttcagacgc tcgccgtaac gcagcacgtc
    56161 aaccacgaca ctggaacccg ctttctgggt acagccaagc gatttatctt ccagcgtggt
    56221 gataccgcct gctttgttcc ccggtgatgg gttttcgtag atcggctggt catgggcaat
    56281 aaagtactgc ttgaagtcat tgaccatggt gaccagtttt tcaaacgttg cttcgtcgcg
    56341 gcaatggtcc atcagcaact gctctgcgcc aaacatctcc ggcacttcgg tcagtacggt
    56401 agtaccgccg ttagcaatca cgtagtcaga gaaacgcccc agcatcgggt tagcagtaat
    56461 accagaaaga ccgtcagaac caccgcactc cagaccaaac ttcagttcgc tgagtttgcc
    56521 cggctcgcgt ttatcgttgc gcatcacgct atacagctga tgcaaatgcg cgatcccggc
    56581 ctcgatttca tcatcctgct gttggcagat catgaaatga acgcgttcag gatcgatatc
    56641 gcccaacgtt tcacggaatg cggcaacctg gttattttcg caacccagac caatcaccag
    56701 cactgcgccc gcgttcgggt ggcgcaccat gttttgcagc atggtgcggg tattgatgtg
    56761 atcgtcgccc agttgtgagc agccgtaggt gtggctgaag aggaacacgc cgtcggtacc
    56821 ttcagcgttg ttggtctctt tcaggaaacg attttggatc tgccgcgcga tgccgttgac
    56881 acagcccacg gttggcagga tccacagctc attacgcacc ccgacatcac cgttagcgcg
    56941 acgatagatc tgcacttcac gatctgccgc ttgcgcaggc agatcctgaa aatcaggttg
    57001 atagcgatac tgatccagat cgctcagatt cgtgcgcgta ttgtgggcgt gaacgtgttc
    57061 ccccgccgca atatccgcca atgcataacc aatcggcagg ccatatttaa tgacgttggc
    57121 cccttttgcg atatccgtta acgcaaattt atgtccacga gcaacatcct ggcgcagcgt
    57181 aacagtctgg ttatcgacac tgacttctgt gccttcagcc aaatccgcta aagcaaccgc
    57241 gacgttatcc agcgcatgga tcttgatgta ttgcatatca accccagacc ttagttcagt
    57301 tcaatggcga agtagtcacg cgcattgtta aagcaaatat ttttcaccat ctcgcccagc
    57361 aggttgatgt ccgccggtgc ttcgcctgct tccacccagc gaccgatcat ctggcacaga
    57421 atgcggcgga agtattcgtg acgggtgtat gacaggaagc tacggctgtc agtcagcatg
    57481 ccgacaaagc ggctcagcag accgagctgc gccagttggg tcatctgacg ttccataccg
    57541 tctttctggt cgttaaacca ccagccggaa ccgaactgca ttttgcccgg cataccttcg
    57601 ccctggaagt taccgatcat ggtgcccagc acttcgttat cgcgcgggtt caggcagtag
    57661 agaatggttt tcggcagcag gttttcttcg ttctgcttgc tcagcagctt agatagctct
    57721 tccgccatcg gacggtcgtt gatggagtca aagccgacat ccggccccag cagtttgaac
    57781 tgacgcaggt tgttattacg cagtgcgcca atgtggtact gctgtaccca tccgcgacgt
    57841 gcatattcgg caccaaggaa caccagcacc gcagttttga actgtgctac ttcgtgctcg
    57901 ctcagggttt cgcctgccag acggcgcgcg aggatgctgt ccagttccgc ttcgttcgct
    57961 tcagcaaaca tcaccacatc cagcgcgtgg tcagacactt tacagccgtg agcggcgaag
    58021 tgatccagac gtttagtcag ggcagtttgc aggtcagcaa agcggcgaat gtcggtatca
    58081 gaaacttcgc ccagcttcgc catgtagtcg ttaaaggtcg cctgttcaat gttaaaggct
    58141 ttgtccggac gccagctcgg cagcacttta atggtgaaag agccgtcttt ggcgatctct
    58201 gcgtgatgct ccagagaatc gatcgggtca tcggtggtgc cgaccatttt cacgttcatc
    58261 tgctgcatga tgccgcgcgc ggagaagtta tcctgcgcca gcagttcgtt acattcgttc
    58321 cagatttcat cggcagttga cggagaaagc aatttgccag tgataccaaa cggacgacgc
    58381 agttcgaggt gcgtccagtg gtataacggg ttgccgatag tgtgcggaac agtcgccgcc
    58441 caggcgtcaa atttttcacg gtcagacgca tcaccggtgc acagacgctc ggccacaccg
    58501 ttggtacgca tagcgcgcca tttgtagtga tcgcccttca accagatgtc atacaggttt
    58561 ttaaaacgat agtcttccgc aatctgctgc ggcggcaaat ggcaatggta atcgaaaatc
    58621 ggctggtctt ttgcgtagtc gtgatacaga cggcgggcaa attcagtatc taacaggaaa
    58681 tcttcagtca taaacggagt cattttcgtc ttcctctcaa cgagtgagct agcttgctta
    58741 tggtgcgatg ctgacaaagt tatcacacca atttccagag tccgaagata ttttcgtgag
    58801 ttagatcaat aaacgtagtt aaaaaaatta ctctcaaagt ggtaaatctc gctgcaggcc
    58861 gcgccagtac tggcctcgtc gtcgtcaggt aatgtcccta caaatattcg cacatttgtg
    58921 atggctctca ccttttaaag ttgtatgaca agttatcttt ctgccgtcgc aaatcataag
    58981 tcgacggaat gcaaattgcc gattcattca tttgttagat gaatcgggtt aaccggtacg
    59041 gaagccgaat tagcacgaaa ctttcatggc aacgttcggg gcgtgccggt tttttttcgg
    59101 ttacccggtc gtaactaaca tcttcagcct ctggcgggat gatggccgcg cttcctgcgg
    59161 atataacaaa acgatgaggt tttacatgcg taaaattaaa gggttacgtt ggtatatgat
    59221 cgcactggtg acgctcggca ccgtgcttgg ttacctgacg cgtaacactg tggcggcagc
    59281 tgcgccaact ctgatggaag agttaaacat ctccacccaa cagtattcct atatcatcgc
    59341 agcgtattct gctgcttata cggtcatgca accggtagcg ggttatgtac tggatgtgct
    59401 gggtacgaaa atcggttatg caatgtttgc tgtactgtgg gccgtgttct gtggtgcaac
    59461 cgcgctggca ggtagttggg gtggcctggc ggttgctcgt ggtgcggtcg gtgccgcgga
    59521 agccgcgatg attccggcgg gtctgaaagc cagctccgaa tggttcccgg caaaagagcg
    59581 ttccatcgcg gtaggttact ttaacgtagg ttcttcgatt ggtgcgatga ttgcgccgcc
    59641 gctggtggta tgggcaatcg tgatgcacag ctggcagatg gcatttatca tctccggtgc
    59701 gttgagcttt atctgggcga tggcatggct gattttctac aagcatccgc gcgaccagaa
    59761 acatctgacc gatgaagaac gcgactacat tattaatggt caggaagccc agcaccaggt
    59821 tgacacagcg aagaaaatgt ccgttggtca gatcctgcgt aaccgtcagt tctggggtat
    59881 cgcgctgccg cgcttcctgg cagaaccggc atggggtact tttaacgcgt ggatcccgct
    59941 gttcatgttt aaagtttacg gctttaacct gaaagagatc gcgatgtttg cctggatgcc
    60001 gatgctgttt gctgacctcg gttgtatcct cggtggttac ctgccaccac tgttccagcg
    60061 ttggtttggt gtgaacctga tcgtttcccg taagatggtc gtaacgctgg gtgcggtgct
    60121 gatgattggc ccgggtatga tcggtctgtt caccaacccg tatgtcgcga ttatgctgct
    60181 gtgtatcggt ggttttgctc accaggcact gtctggcgca ctgattacgc tctcgtctga
    60241 cgtgttcggt cgtaacgaag tggcgacggc gaacggttta accgggatgt ccgcatggct
    60301 ggcaagtacg ctgtttgcac tggtagtcgg tgcactggct gacaccatcg gcttcagccc
    60361 gctgttcgca gttctggcag tgttcgacct gttaggtgcg ctggttatct ggaccgtgtt
    60421 gcagaacaaa ccagcgattg aggtggcgca ggaatcacat aacgatcccg caccgcaaca
    60481 ttaaggcttc gtgtaagttt tagtttccct tcaaagccgc cttctcaggc ggctttttca
    60541 tcactgcgag tagagctaaa ctcgcaaaag tggtataaca aatatagtct gccgtatcat
    60601 gcctggagcg catatggaaa tcactgaacc acgccgtttg tatcaacaac ttgccgctga
    60661 tctgaaagag cgcatcgaac agggcgtcta tctggtgggt gataaactgc ctgccgaacg
    60721 ctttattgcc gatgaaaaaa acgtcagccg caccgtggtt cgtgaagcca tcatcatgct
    60781 ggaagttgaa ggctatgtcg aagtgcgtaa aggttcaggt attcatgtgg tttccaacca
    60841 gccgcgccat cagcaggcgg ctgacaataa tatggaattc gccaattacg gtccgtttga
    60901 gttgctccag gctcgccagc tcatcgaaag taatattgcc gagttcgcgg caactcaggt
    60961 cacaaaacag gacatcatga aattgatggc cattcaggag caggcacgcg gcgaacaatg
    61021 cttccgtgat tccgagtggg atttgcagtt ccatattcag gtagccctgg cgacgcagaa
    61081 ctccgccctg gcggctatcg ttgaaaaaat gtggacccag cgtagtcata acccgtactg
    61141 gaaaaaactg cacgaacaca ttgatgcccg taccgtcgat aactggtgtg atgaccacga
    61201 tcaaatcctc aaggcgctga ttcgcaaaga tcctcatgct gctaagctgg caatgtggca
    61261 gcacctggaa aacaccaaga tcatgttatt taacgaaacc agcgacgatt tcgagttcaa
    61321 tgccgaccgc tatctgttcg ccgaaaaccc ggtggtgcat ctcgatacag ccaccagcgg
    61381 cagtaaatga aattcctgtc cgacaggcgc tacagtgcgc ctgtttgtct cgtcggtaag
    61441 cgaaaagtat aaagtgtcag cctgtgtaaa tcctctcgcc tccctcccct gcattcagca
    61501 aaatcagact ccatggacat gtaattttga taacgaacaa cgttgacctt tgttacaatt
    61561 agattcaatt tgaatttatg cttttgaatg ctttcttatc tcacgattta acagggaata
    61621 gttcaggctg tgttgatgta tcaaacccgc agaacatacc aagacagcaa taacattgcg
    61681 gtagtgcatc atttaaaacc agcgtggcgt taaccgattc accaggaata atgaatggaa
    61741 cttttgaccc aattgctgca agccctgtgg gcgcaggatt ttgaaaccct ggccaatccg
    61801 tcgatgattg gcatgttgta ttttgtcttg tttgtcattt tgttccttga aaacggcttg
    61861 cttccggcgg cctttttacc gggcgacagt ttactggtac tggtcggcgt attgattgcg
    61921 aaaggcgcga tgggctatcc gcaaacgatt ctgctgctga ccgttgccgc cagcctcggt
    61981 tgctgggtca gctatattca ggggcgatgg ctgggcaata cccgcaccgt acaaaactgg
    62041 ctatctcatt tacccgcgca ttatcatcaa cgcgcacacc atctttttca taaacacggt
    62101 ttatcggcgc tgttaattgg tcgctttatt gcgtttgtca gaacactgct gccgacgatt
    62161 gccgggttat cagggctgaa taacgcgcgc tttcagttct tcaactggat gagtggtctg
    62221 ctgtgggtgt tgatcctgac aactctgggt tacatgctcg gcaaaacacc ggtattttta
    62281 aagttcgagg accagctgat gtcatgcctg atgctgctcc cggtggtgct gctggtgttt
    62341 ggcctggcag gttctctggt cgtgttatgg aaaaagaaat atggaaatcg ggggtaaggg
    62401 atgcaaatac ctcgcatgtc acttcgccag ctagcctggt ccggcgctgt tttacttctg
    62461 gtcagcacac tattgctggc ctggtccgcg gttcgccagc aagagtctac gctggcgatt
    62521 cgtgccgttc atcaagggac aacgatgcca gacggttttt caatctggca tcaccttgac
    62581 gctcacggca ttcctttcaa aagtatcacc cccaaaaacg acactctgtt aattaccttt
    62641 gactccagcg accagagcgc cgccgcaaaa gcggtcctcg acagaacatt gccccatggc
    62701 tacatcattg cgcagcagga caataacagt caggctatgc agtggctgac ccggttgcgg
    62761 gataactctc atcgcttcgg ataacttcct gttatccgaa acagatcact cactttggtg
    62821 atttcaccgt aactgtctat gattaatgag gcggtggtta acacgaccgc ttcgttgtct
    62881 ggacaatcgt tcctttgtaa taggtccgaa tcacaatgga aggttcaaga atgaaatacc
    62941 gcatcgcttt agctgtttct ctctttgctc ttagtgccgg tagttatgcc actaccctgt
    63001 gtcaggaaaa ggagcaaaat atccttaagg agatcagcta tgccgaaaaa caccaaaacc
    63061 agaatcgtat tgacggtctg aataaagccc tgagtgaagt ccgggccaac tgttcagata
    63121 gccaactgcg tgccgatcat cagaagaaaa tcgcaaagca gaaagatgag gtggcggaac
    63181 gccagcaaga tttagccgag gcgaagcaaa aaggcgatgc agataagatt gccaaacgcg
    63241 aacggaaact ggcagaagcg caggaagagc tgaaaaagct ggaagcgcgc gactactaac
    63301 tcacaatagt cactacttac tcacctggag aaaactatgt cgaaagaaca cactacggaa
    63361 catctgcgtg ctgagttgaa atccctttcc gatacgctgg aagaggtgct tagctcatct
    63421 ggcgagaagt caaaagaaga gttgagtaag attcgtagca aagcggagca ggcactgaaa
    63481 cagagccgtt atcgcctggg tgaaaccggt gatgccattg ccaaacaaac ccgtgtcgcg
    63541 gcggcgcgtg ccgatgagta tgtgcgtgaa aatccgtgga cgggcgtggg cattggcgca
    63601 gcaatcggtg tagtgctcgg cgttctgctg tcgcgtcgtt aattatggcg gacactcatc
    63661 acgcgcaagg gcccggtaaa agcgttctgg gcatcgggca gcgaattgtt tccatcatgg
    63721 ttgaaatggt ggagacacgt ctgcggctgg cggtggtgga gctggaagag gaaaaagcga
    63781 atctctttca acttttactg atgctgggcc tgacgatgct tttcgctgca tttggtctta
    63841 tgagcctgat ggtgctaatt atctgggcgg ttgatccgca atatcgcctg aatgcgatga
    63901 ttgccaccac cgtggtgttg ctgctactgg cactgattgg cggcatctgg acgttacgta
    63961 aatcgcgtaa gtctacgttg ctgcgccaca cgcgccatga gctggcaaac gatcggcagc
    64021 tgctcgagga ggagtcccgt gagcagtaaa gtcgaacgtg aacgacgtaa ggcgcaactg
    64081 cttagccaga tccagcaaca acggctggat ctttccgcca ctcgtcgtga atggctggag
    64141 gcaacaggcg cttacgatcg tcgctggaat atgctgttga gtctgcgctc ctgggcgctg
    64201 gttggcagta gcgtgatggc tatctggacg attcgccatc ctaatatgct ggtccgctgg
    64261 gccagacgcg gttttggtgt atggagcgcc tggcgtctgg tgaaaacaac cctcaagcaa
    64321 caacagcttc gcggttaact tcctctctgg ccggagaaat tccggcctta ttcctcaaat
    64381 tttttgaaaa tatttgacag ttttccttgc taacaatcac gcttcgccac gtttatgatt
    64441 ctctccatcg acagcaacga cgctaatagc gcgcccttgc acaaaaaaac aatcagcagc
    64501 ctgagcggcg cagtggagag tatgatgaaa aaattagaag atgttggtgt actggtagcg
    64561 cgtattttaa tgccgattct gtttattacc gcaggctggg gaaaaattac tggctacgcg
    64621 ggtacccaac aatatatgga agcaatgggc gtccccggct ttatgctgcc gctggtgatt
    64681 ctgcttgagt ttggtggtgg tctggcaatc ctgttcggtt tcctgacacg taccacagcc
    64741 ctgtttactg cgggctttac gctgctgacg gcatttttat ttcacagcaa ttttgcagaa
    64801 ggcatgaact cgctgatgtt tatgaaaaac ctgactattt ctggcggatt cctgctgctg
    64861 gcaattaccg gtccaggcgc attcagcatc gaccgcctgc tgaataaaaa gtggtaagca
    64921 cgcgctatac ttaacgataa aaaacgaggg ggaagctcct cgtttttgct attggaggat
    64981 agaaaaatgg gtcaactgat tgacggcgtc tggcatgaca cctggtacga taccaaatcc
    65041 accggcggta aatttcaacg ttcagcttcc gcatttcgta actggctcac tgccgatggc
    65101 gcgccaggcc ccactggcaa aggcggtttt gccgcagaga aagatcgtta tcatctctat
    65161 gtttcactcg cctgcccgtg ggcacaccgc acgctgatca tgcgtaagct caaaggactg
    65221 gaaccgttta tttccgtttc cgtagtgaac ccgctgatgc tggaaaacgg ctggaccttt
    65281 gatgacagtt ttccgggagc aagcggcgac acgctctatc aacatgaatt tctgtatcag
    65341 ctttatctcc acgccgatcc acactacagc ggacgagtta ctgttcccgt gctgtgggac
    65401 aaaaaaaacc acaccatcgt cagcaacgaa tcagcagaaa tcatacgcat gttcaatacc
    65461 gcgtttgatg cgctgggtgc gaaagctgga gattactacc caccagccct gcaaccgaaa
    65521 attgacgaac ttaacggctg gatttacgac accattaaca atggcgtgta taaagccggt
    65581 tttgccacca gccagcaagc ctacgacgag gcggtggcga aagtgtttga atcgctggcg
    65641 cgactggaac agattttagg tcagcaccgt tacctgaccg gcaaccagct aaccgaagcc
    65701 gatattcgcc tgtggaccac gctggtgcgt tttgatccag tgtatgtgac ccacttcaag
    65761 tgtgataagc accgcatcag cgattacctg aatctgtatg gcttcctgcg cgatatctac
    65821 cagatgccgg gaattgccga aacagtcaat ttcgatcaca tccgtaatca ttacttccgc
    65881 agccataaga ccatcaaccc tacggggatt atttcaattg gtccgtggca ggatctcgat
    65941 gaaccgcatg gacgagatgt tcgcttcggt taaaaaaagg caccttacga ggtgcctctg
    66001 ataattagct aagtacgtgt tgttcatgtc ggatgcggcg taaacgcctt atcaaaccta
    66061 caaaacattt atattcaata tgttgcaatg accgcgcagg ccagataagc gtagcgcatc
    66121 tggcaatttt gcgtttgccc ttatccttca cagcgcctta ttaattcatc gcgataatat
    66181 ttactgccat ttcattcacg tctattctta atttgctgct ttaaaaacaa gtgattgagc
    66241 aaaattgagg caaaaatgga ctggtatctg aaagtactaa aaaattatgt cggtttccgg
    66301 ggtcgtgcgc ggcgcaaaga gtactggatg tttattctgg tcaacatcat ctttacgttc
    66361 gtgctggggc tactggataa aatgttaggc tggcaacgtg ccggtggcga aggcatcctg
    66421 acgacaatct acggtattct ggtgttttta ccatggtggg cagttcagtt ccgccgcctg
    66481 cacgacaccg accgctcggc gtggtgggca ctgctattct taatcccgtt tatcggctgg
    66541 cttattatca tcgtctttaa ctgccaggcg ggtacgccag gcgaaaaccg ctttggacca
    66601 gatccgaaac tggaacaaga ataataatta agcaccttgt aaaaggtgct taatcgatta
    66661 ttttccgcta aaaagtttgg gaatttcccg cagacaccag gatttcgcct cccccatact
    66721 gtcacgacgc caggccataa taatatcgat ctcgctggtc gattccgggc tgacgacacg
    66781 caaccgccct tccgcaatat ctttttcgac catcggatac ggcatcgtcg ccacgccaag
    66841 ccccgccagt aatgcctgac gtttatcttc aatcgtgctc accgttaagc gcggctgttt
    66901 gtccagcaac tgtacggtca acaccgggcg ctcacgagcg gtatccgcca ccgcaattcc
    66961 acgatatttc acgcgcgtca cttcagataa cggttccggc tcctgatgaa tcgggtgatc
    67021 cggcgcggca acatagacgt tcattaaggt atagagtttg cgcgagttga tctccgacga
    67081 ggaacgaaaa tgcatatccg gcgcgataac gatatccgcc cgcccctgct ccagccgttc
    67141 ccacgccccc gccagcactt cggtgataat tgccagttgg gtattggctt ttgccgccag
    67201 tttgtcgatt aacgggaaaa aggcaggtgt cggtaccagc gcctcggtca caatggtgag
    67261 atgcgtttcc caaccgcgcg cgagggcttc cgcatcggta gtcagtttat ctgcggcttc
    67321 cagcaaaacg cgccctcgct ccagcaacat cctcccgaca ttggtgaatt tggtgcgatg
    67381 gcccgagcgg tcaaacagca ccacatccag ctcttcttcc agtttttgca tggtgtagct
    67441 aagtgcggaa ggcacgcgtc ccagctcatc cgccgccgcc gcaaaactgc cccggcgatc
    67501 gatcgcatcc ataacccgta gtgcttccag cgttaatgcc ctttctttgg ccatttcgtt
    67561 ctcattcagg aaatttgaac ataccgggca gaatatctgg ctaacaatgt agcgtccagc
    67621 cccttaccat aaaaggaagt aaagagaggt caagaattat gattactacc cgaactgcca
    67681 ggcagtgtgg acaagcagac tacggatggt tgcaggcccg gtatactttt tcctttggac
    67741 actacttcga cccgaaattg ttaggctatg cctctctgcg cgtgcttaac caggaagtgc
    67801 tggccccagg tgccgccttt cagccacgaa cctatcccaa agtcgatatt ttaaatgtga
    67861 ttctggatgg agaagctgag tatcgcgaca gcgaaggcaa tcatgttcag gccagcactg
    67921 gtgaggtgtt gctgctctct acccagccgg gtgtcagcta tagcgaacac aatctcagca
    67981 aagacaaacc gttaacgcga atgcagcttt ggctggatgc ctgcccgcag cgagagaatc
    68041 cgctgattca aaagctggcg cttaatatga gcaagcagca attaatcgcc tcgccagaag
    68101 gtgggatggg aagcctgcaa ttgcgccagc aagtgtggct gcaccatatc gtgctcgaca
    68161 aaggcgaaag tgcgaatttc cagttgcatg ggccacgcgc gtatttgcaa tcgattcacg
    68221 ggaaatttca tgcgcttacg catcatgaag agaaagcggc gctaacctgc ggtgatgggg
    68281 cgtttattcg tgacgaggct aacattacgc tggttgccga ttccccactg cgcgctttgc
    68341 tgatagattt gcctgtctag ttgtttttac agggagatga tgatgagtaa aaaatcggcc
    68401 aaaaagcgcc agccagtgaa gcccgtggtg gcgaaagaac ctgctcgtac cgccaaaaat
    68461 tttggctatg aagagatgtt gagcgaactg gaagccatcg tcgcggatgc tgaaacgcgt
    68521 ttagccgagg atgaagctac cgcgtaaaga caggttgccg gatgcggcgc aaacgcctta
    68581 tccggcacaa tacccaaaac cgggcgttta tctggccttg ctcgccataa tctcgataat
    68641 ctgccgatcc gtttgctgca tcgaatggct tgctaacgca cacaggttgg caatcgactg
    68701 ctcaacatca tgcgccacaa tcccttcatt gccggtcacg gcggtatcat ccagcgccat
    68761 taacaccgct ttccacgcag ccgaagcact ggtcgaaacc ttcatcgcgc agctgttcga
    68821 tgcaccatcg caaatcatgc cgctgacatc gccgatcata ctgctgatcg ccatcgagat
    68881 ggtttcataa cgcccatcca ccagccatgc catcccggca gcggccccca ttgctgcggt
    68941 cgttgcggca cacagcgcag acaaacgcgg taactggtta tggatgtaaa tcgcgctcaa
    69001 atgcgaaagc atcagcgcac gcgccagccg ttcatcatcc gctccgaagt gttcagctac
    69061 caccaccacg ggcattgttg cggtgatccc ctggttaccc gagccggagt tactcattgc
    69121 cggaagcgta gcgccgccca tacgcgcatc ggatgccgcg ctggtacgaa tcacaatgga
    69181 tgaagagaga tctttcgcca gcaaaccgcg cgcgcactgt ttttccagcg tcgcaccaat
    69241 atgcagcccc cagttaccgc tcaaaccttc ctgcgataac gcacaattta acttcgcaga
    69301 atcgagaata aagcggatcg ccgcaaacgg gacttcattg acgaacttca ggatctcagc
    69361 cagcgtcgtc ctggaaagca ccgtcagcgg cgactcttgc tcgccctctg ccacacacgc
    69421 ctgctgggta aacaccacac cattgtgcgt ctcaatatgc acaatgttgg tatgcccgcc
    69481 gacgatggtg acacacgccc atttctcacc gttccagact ttggcgcgtg agaagaggat
    69541 ttcatcgcaa ggttcctgga tcttaactga gactttcccc gccgccagca gtgctttggc
    69601 atcggaaatt gcctgcgcag ttgcgtcttt cagcacttcc agcccggcgt tagcatttcc
    69661 acctaacgct cccagcgccg ccgcaattgg cagccccacc attcctgtac cgggaacggt
    69721 gacacccaga ccgttcttca tcagatttgg cgaaacccag gcttctacac gttcaaccgg
    69781 accttccagt tcagccgcag caaccgccgc cgccagcgcc agtgaaatcg gttcagtaca
    69841 ccccagcgcc ggttttactt cctcctgaac ggcgaggatg taacgctgcc ataacggatt
    69901 taaagtcgaa tcaaacatat taaaaacctt aaaatttcag gtaaatcaag aaaatgccag
    69961 gaacggagaa acacaaagca acaaaccagt gacgataatc aggtacaaag acatcccttt
    70021 gtatttgtgc aatgccggta ctttgtaaac cagccacgcc gggatcaggc accctaccat
    70081 gccgaaaatc gggctacaga tagaggtgaa gctcaacacc ggggcgttca gtacgatggc
    70141 gctccaggcc agcaaaatgg cgaaaatcat gatgccgcgc tgaacgagat tttcgttaat
    70201 cttctcggca ggtatcttgc gacgcaggat gttcattacg atcccttgcg ttgcttcgcg
    70261 aaagcctaaa tagacgccaa agaatgcagt cattacagca aagatattga gaatgacgct
    70321 gaccactttc acccacgctg cgccgtcacc gctaataaac tgtgcggcaa tcgccagcgc
    70381 ggaaatattc tgctcgtagg cttttaccgc ttcgtcatgt cccatcgcca gcgtgaacga
    70441 cacggcgtag aaaaagacgg tgacaaacaa aatgccaaac gcgatattca ttgcccgcaa
    70501 tgctttatgc cgcgccactt caattgattt ttcccgcgag cgataagaga tcaccatcgg
    70561 gcttaacgtc tggataaata gaatcgacgt cagggtaaac ggcagcgtaa taatggcgtt
    70621 tttcatcagc agccccagcg gcggtagcga accgacgtta tacagatgcc acattcccac
    70681 catcgacacg cccagcgccg cgaccaccag cagcttggtc agcaccatgc cggtcgaaat
    70741 tttgaataac aatttctcgc cgcgtgagga gatcgccacc agaatgcaaa tcagtaccag
    70801 accataaaag ggactgtctg aca
//
LOCUS       DAPOXO010000014        69771 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPOXO010000014 DAPOXO010000000
VERSION     DAPOXO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 69771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69771
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.014"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..949
                     /gene="caiC"
                     /locus_tag="ROH59_001191"
     CDS             <1..949
                     /gene="caiC"
                     /locus_tag="ROH59_001191"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HDX4803705.1"
                     /translation="YYSAWQCALRDDDIYLTVMPAFHIDCQCTAAMAAFSAGATFVLV
                     EKYSVRAFWGQVQKYRATVTECIPMMIRTLMVQPPSVNDRQHCLREVMFYLNLSEQEK
                     DAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLP
                     AGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFVDRR
                     CNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEE
                     EFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK"
     gene            1058..1843
                     /gene="caiD"
                     /locus_tag="ROH59_001192"
     CDS             1058..1843
                     /gene="caiD"
                     /locus_tag="ROH59_001192"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HDX4803706.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGVVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     gene            1849..2439
                     /gene="caiE"
                     /locus_tag="ROH59_001193"
     CDS             1849..2439
                     /gene="caiE"
                     /locus_tag="ROH59_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HDX4803707.1"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVLAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(2558..2953)
                     /gene="caiF"
                     /locus_tag="ROH59_001194"
     CDS             complement(2558..2953)
                     /gene="caiF"
                     /locus_tag="ROH59_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HDX4803708.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(3214..6435)
                     /gene="carB"
                     /locus_tag="ROH59_001195"
     CDS             complement(3214..6435)
                     /gene="carB"
                     /locus_tag="ROH59_001195"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDX4803709.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHSMEEALAVAA
                     EVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     ERLKLKQPANATVTTIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            complement(6453..7601)
                     /gene="carA"
                     /locus_tag="ROH59_001196"
     CDS             complement(6453..7601)
                     /gene="carA"
                     /locus_tag="ROH59_001196"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDX4803710.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEPYSWTQGSWTLTGGLPEAKKEDELPYHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIALIEQYRKTAK"
     gene            complement(8057..8878)
                     /gene="dapB"
                     /locus_tag="ROH59_001197"
     CDS             complement(8057..8878)
                     /gene="dapB"
                     /locus_tag="ROH59_001197"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDX4803711.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL"
     gene            complement(9039..9404)
                     /locus_tag="ROH59_001198"
     CDS             complement(9039..9404)
                     /locus_tag="ROH59_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDX4803712.1"
                     /translation="MTYGEAYLEGWKNIFNYEGVSNRFEFWSFMIGSGVICLLPLLCW
                     WLAVTINNDYGVFIFFALPASFILTLIFAVPAIALAVRRMHDIGYSGWWVTIVVLIPV
                     TGVILLILCCLPSKSQDQA"
     gene            complement(9427..10341)
                     /gene="rihC"
                     /locus_tag="ROH59_001199"
     CDS             complement(9427..10341)
                     /gene="rihC"
                     /locus_tag="ROH59_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HDX4803713.1"
                     /translation="MHLPIFLDTDPGIDDAVAIAAAIFTPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYNFVEHNRQPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVQVALDLDVKGFQQWVAEVLALAL"
     gene            complement(10407..11357)
                     /gene="ispH"
                     /locus_tag="ROH59_001200"
                     /gene_synonym="lytB"
     CDS             complement(10407..11357)
                     /gene="ispH"
                     /locus_tag="ROH59_001200"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDX4803714.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     gene            complement(11359..11808)
                     /gene="fkpB"
                     /locus_tag="ROH59_001201"
     CDS             complement(11359..11808)
                     /gene="fkpB"
                     /locus_tag="ROH59_001201"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDX4803715.1"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            complement(11916..12410)
                     /gene="lspA"
                     /locus_tag="ROH59_001202"
     CDS             complement(11916..12410)
                     /gene="lspA"
                     /locus_tag="ROH59_001202"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDX4803716.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILVVMMYRSKAAQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            complement(12410..15226)
                     /gene="ileS"
                     /locus_tag="ROH59_001203"
     CDS             complement(12410..15226)
                     /gene="ileS"
                     /locus_tag="ROH59_001203"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDX4803717.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKTKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVSDYTILGTVKGAELELLRFTHPFMDFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVIALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     gene            complement(15269..16210)
                     /gene="ribF"
                     /locus_tag="ROH59_001204"
     CDS             complement(15269..16210)
                     /gene="ribF"
                     /locus_tag="ROH59_001204"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDX4803718.1"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            complement(16218..16436)
                     /locus_tag="ROH59_001205"
     CDS             complement(16218..16436)
                     /locus_tag="ROH59_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 family protein"
                     /protein_id="HDX4803719.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSARKIAVGGQFLPMICAIAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            16539..16802
                     /gene="rpsT"
                     /locus_tag="ROH59_001206"
     CDS             16539..16802
                     /gene="rpsT"
                     /locus_tag="ROH59_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDX4803720.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     gene            17191..18564
                     /locus_tag="ROH59_001207"
     CDS             17191..18564
                     /locus_tag="ROH59_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4803721.1"
                     /translation="MSSVLETDKSSASDSLPLIQRISYGSLDVAGNLLYCFGSTYILY
                     FYTDVAGISLAVAGIILLLARIVDGIDAPVWGIIIDKTHSRYGKCRPWFLWLPLPFAV
                     FSALSFWSPDISMTGKTIYSAISYMLASILFTGLNTPLSAILPLMTLSPKERLVLNSY
                     RMTGGQIGVLLMNATALPLVAFLGNGNDKAGFIYTAIVFSVISCALTLFAFKNIRELD
                     TDKIQQEPRLPMKKSFSAMKGNWPWILMVLANLIFWIALQQRNTTIVYYLTYNLDRKD
                     LVPLINSLATIQILFIIAIPFFSRYLSKTWIWITGLLVAMFGGGLMWLAGDNIPLMIA
                     AWMLANIGSGIACSMPFAMLGFAVDFGRWKTGIKATGILIAFGSTFCIKMGSGIGTAF
                     AAWIMNSFGYIPNQPQTAAGLDGISWAFIWVPAVLFALAAIPLLFFRKYEAMEECIQH
                     DLQVHNP"
     gene            18592..20631
                     /locus_tag="ROH59_001208"
     CDS             18592..20631
                     /locus_tag="ROH59_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HDX4803722.1"
                     /translation="MSFIKQDPHRLVWQQDDRYLWIEAWGENSLRVRSGRHLPMMRNE
                     NWALTEEKGDAVAYITYEEKQATLQNGKITAIVNLQGQISFWRNAEKCLLQEFWRQRG
                     EIGEDESAHGQYVSALNLQAREFKPIPGGKYTIKARFEANDGEKLFGMGQYQQPNLDL
                     KGCMLELAQRNSQASVPFLLSNRGYGFLWNNPAVGRVTFAQNGTEWVAEVSEQLDYWV
                     TAGDTPAEISAAYARVTGTPPMMPDYAMGFWQCKLRYRNQQELLEVARGYKQRNLPIS
                     VIVIDFFHWPNQGDWMFDLRDWPDPDAMIAELKEMGIELMVSFWPTVDNRTESYREMK
                     ENGWLVHTERGLPINMDFLGNTTFFDATHPGAREYVWNKAKRNYYDKGVKLFWLDEAE
                     PEFGVYDYDNYRYYAGPVLEVGNIYPRMYAKTFFDGMTAAGEKQVINLLRCAWAGSQK
                     YGALVWSGDIHSSFRSLRNQFAAGLNMGIAGIPWWTTDIGGFHGGNIHDPKFHELLIR
                     WFQWGVFSPVMRLHGNRDPQVLPEQPYRDGIAQCPTGAPNEVWSYGEETGEILTSCLQ
                     LREKLKSYISKIMAETHEKNSPIMRTMFFEFPDQAESWNIYDQYCFGPDLLVAPVMHE
                     GTRSRDVWLPAGETWIDFYTHEHYAGGQTLHHCAPLHQIPVFIREKGKYRQIFPV"
     gene            complement(20689..21588)
                     /gene="nhaR"
                     /locus_tag="ROH59_001209"
     CDS             complement(20689..21588)
                     /gene="nhaR"
                     /locus_tag="ROH59_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HDX4803723.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSSLFSPASR"
     gene            complement(21654..22820)
                     /gene="nhaA"
                     /locus_tag="ROH59_001210"
     CDS             complement(21654..22820)
                     /gene="nhaA"
                     /locus_tag="ROH59_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HDX4803724.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAVLAMIMANSGATSGWYHDFLET
                     PVQLRVGTLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLEGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     gene            complement(23055..24314)
                     /locus_tag="ROH59_001211"
     CDS             complement(23055..24314)
                     /locus_tag="ROH59_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDX4803725.1"
                     /translation="MFTNVNVDCCKTPGCKNLGLLNSQDYVAQGKNILCRECGYLFPV
                     ISEQSLNIYRNIVNHSWRGLICQCSTCGGTSLKKYGYSAQGQRRMYCHHCEKTFITLE
                     HVITTPRGAQLALMIEQGEALADIRKSLLLNSTGLSRELLKLAREANYKESRQCFPAS
                     DITLSTRAFRVKYNGSNNSLYALVTAEEQSGRVVAISTNYSPSAVEQHYQYTSNYEER
                     MSPGTLAHHVQRKELLTMRRDTLFDIDYGPAVLHQNDPGMLVKPVLPAYRHFELVRIL
                     TDEHSNNVQHYLDHECFILGGCLMANLQHIHQGRCHISFVKERGVAPATIDFPPRLFL
                     SGGVRNNVWRAFSNRNYSMAVCNLTGSKKVREMRHATLNSATRFIHFVENHPFLISLN
                     RMSPANVVSTLDILKHLWNKKLEHGTI"
     gene            complement(24443..25936)
                     /locus_tag="ROH59_001212"
     CDS             complement(24443..25936)
                     /locus_tag="ROH59_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HDX4803726.1"
                     /translation="MQKTLMASLIGLAVCTGNAFSPALAAEAKQPNLVIIMADDLGYG
                     DLATYGHQIVKTPNIDRLAQEGVKFTDYYAPAPLSSPSRAGLLTGRMPFRTGIRSWIP
                     SGKDVALGRNELTIANLLKAQGYDTAMMGKLHLNAGSDRTDQPQAQDMGFDYSLVNTA
                     GFVTDATLDNAKERPRYGMVYPTGWLRNGQPTPRADKMSGEYVSSEVVNWLDNKKDSK
                     PFFLYVAFTEVHSPLASPKKYLDMYSQYMSAYQKQHPDLFYGDWADKPWRGVGEYYAN
                     ISYLDAQVGKVLDKIKAVGEEDNTIVIFTSDNGPVTREARKVYELNLAGETDGLRGRK
                     DNLWEGGIRVPAIIKYGKHLPQGMVSDTPVYGLDWMPTLAKMMNFKLPTDRTFDGESL
                     VPVLEQKALKREKPLIFGIDMPFQDDPTDEWAIRDGDWKMIIDRNNKPKYLYNLKSDR
                     YETLNLIGKKPDIEKQMYGKFLKYKTDIDNDSLMKARGDKPEAVTWG"
     gene            complement(25957..26718)
                     /locus_tag="ROH59_001213"
     CDS             complement(25957..26718)
                     /locus_tag="ROH59_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803727.1"
                     /translation="MSAKRRLLIACTLITAIYHFPAYSSLEYKGTFGSINAGYADWNS
                     GFVNTHRGEVWKVTADFGVNFKEAEFYSFYESNVLNHAVAGRNHTVSVMTHVRLFDSD
                     MTFFGKIYGQWDNSWGDDLDMFYGFGYLGWNGEWGFFKPYIGLHNQSGDYVSAKYGQT
                     NGWNGYVVGWTAVLPFTLFDEKFVLSNWNEIELDRNDAYTEQQFGRNGLNGGLTIAWK
                     FYPRWKASVTWRYFDNKLGYDGFGDQMIYMLGYDF"
     gene            27332..27484
                     /gene="mokC"
                     /locus_tag="ROH59_001214"
     CDS             27332..27484
                     /gene="mokC"
                     /locus_tag="ROH59_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HDX4803728.1"
                     /translation="MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
     gene            complement(27588..28718)
                     /gene="dnaJ"
                     /locus_tag="ROH59_001215"
     CDS             complement(27588..28718)
                     /gene="dnaJ"
                     /locus_tag="ROH59_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDX4803729.1"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(28807..30723)
                     /gene="dnaK"
                     /locus_tag="ROH59_001216"
     CDS             complement(28807..30723)
                     /gene="dnaK"
                     /locus_tag="ROH59_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDX4803730.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            31094..31498
                     /locus_tag="ROH59_001217"
     CDS             31094..31498
                     /locus_tag="ROH59_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HDX4803731.1"
                     /translation="MKSVITISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASIYFKATRSASQTLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            31524..32237
                     /gene="msyB"
                     /locus_tag="ROH59_001218"
     CDS             31524..32237
                     /gene="msyB"
                     /locus_tag="ROH59_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HDX4803732.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPERHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            32386..32952
                     /gene="satP"
                     /locus_tag="ROH59_001219"
     CDS             32386..32952
                     /gene="satP"
                     /locus_tag="ROH59_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HDX4803733.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGIFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(32987..33574)
                     /gene="mog"
                     /locus_tag="ROH59_001220"
     CDS             complement(32987..33574)
                     /gene="mog"
                     /locus_tag="ROH59_001220"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HDX4803734.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARREVSE"
     gene            complement(33689..34642)
                     /gene="tal"
                     /locus_tag="ROH59_001221"
     CDS             complement(33689..34642)
                     /gene="tal"
                     /locus_tag="ROH59_001221"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDX4803735.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAVDQEKLEKMIGDLL"
     gene            34921..36351
                     /locus_tag="ROH59_001222"
     CDS             34921..36351
                     /locus_tag="ROH59_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDX4803736.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDANGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFAMLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNTPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPEIGRQLSPDAWDDVSQE"
     gene            36421..37197
                     /gene="yaaA"
                     /locus_tag="ROH59_001223"
     CDS             36421..37197
                     /gene="yaaA"
                     /locus_tag="ROH59_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDX4803737.1"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISSLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     gene            complement(37237..37533)
                     /locus_tag="ROH59_001224"
     CDS             complement(37237..37533)
                     /locus_tag="ROH59_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDX4803738.1"
                     /translation="MKKMQSIVLALSLVLFAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPYGPPPSPRHNKHNDHRGDHRPGPDKHHR"
     gene            complement(37747..39033)
                     /gene="thrC"
                     /locus_tag="ROH59_001225"
     CDS             complement(37747..39033)
                     /gene="thrC"
                     /locus_tag="ROH59_001225"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDX4803739.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHGGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            complement(39034..39966)
                     /gene="thrB"
                     /locus_tag="ROH59_001226"
     CDS             complement(39034..39966)
                     /gene="thrB"
                     /locus_tag="ROH59_001226"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDX4803740.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICQLDTAGARVLEN"
     gene            complement(39968..42430)
                     /gene="thrA"
                     /locus_tag="ROH59_001227"
     CDS             complement(39968..42430)
                     /gene="thrA"
                     /locus_tag="ROH59_001227"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HDX4803741.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    complement(42457..42576)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            complement(42512..42577)
                     /gene="thrL"
                     /locus_tag="ROH59_001228"
     CDS             complement(42512..42577)
                     /gene="thrL"
                     /locus_tag="ROH59_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HDX4803742.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            complement(42791..43477)
                     /locus_tag="ROH59_001229"
     CDS             complement(42791..43477)
                     /locus_tag="ROH59_001229"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDX4803743.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAYLEPAA
                     RWVAHGSGDIIDNIKVFKTLAESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPAKSDTTADQHQLQALRERAMTLLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
     gene            complement(43877..44017)
                     /locus_tag="ROH59_001230"
     CDS             complement(43877..44017)
                     /locus_tag="ROH59_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803744.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILT
                     AI"
     gene            44113..44829
                     /gene="arcA"
                     /locus_tag="ROH59_001231"
     CDS             44113..44829
                     /gene="arcA"
                     /locus_tag="ROH59_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HDX4803745.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            complement(44889..46241)
                     /gene="creD"
                     /locus_tag="ROH59_001232"
     CDS             complement(44889..46241)
                     /gene="creD"
                     /locus_tag="ROH59_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HDX4803746.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDV
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEDDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELDAPNITLGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDLRKQNLKLNVALNLSGTGDLSVVPGGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHTGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLVLLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTMDDELRIWK
                     "
     gene            complement(46299..47723)
                     /gene="creC"
                     /locus_tag="ROH59_001233"
     CDS             complement(46299..47723)
                     /gene="creC"
                     /locus_tag="ROH59_001233"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HDX4803747.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDAQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPDLGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTAVDVAALF
                     RRVSEARTVQLAEKNITLHVMPTEINVAAEPALLEQALGNLLDNAIDFTPESGRITLS
                     AEVDQEYVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQEGGVLASLRLHRHFT"
     gene            complement(47723..48412)
                     /gene="creB"
                     /locus_tag="ROH59_001234"
     CDS             complement(47723..48412)
                     /gene="creB"
                     /locus_tag="ROH59_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HDX4803748.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFGVEVFERGLPVLDKAR
                     QQVPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSTPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            complement(48425..48898)
                     /gene="creA"
                     /locus_tag="ROH59_001235"
     CDS             complement(48425..48898)
                     /gene="creA"
                     /locus_tag="ROH59_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HDX4803749.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
     gene            49109..49978
                     /gene="robA"
                     /locus_tag="ROH59_001236"
     CDS             49109..49978
                     /gene="robA"
                     /locus_tag="ROH59_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HDX4803750.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            complement(49975..50622)
                     /gene="gpmB"
                     /locus_tag="ROH59_001237"
     CDS             complement(49975..50622)
                     /gene="gpmB"
                     /locus_tag="ROH59_001237"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HDX4803751.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLETRNIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            50674..51201
                     /gene="yjjX"
                     /locus_tag="ROH59_001238"
     CDS             50674..51201
                     /gene="yjjX"
                     /locus_tag="ROH59_001238"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HDX4803752.1"
                     /translation="MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSA
                     TLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRTSVYHQAVIL
                     ALSPFHNAVYQPLQA"
     gene            complement(51280..51606)
                     /gene="trpR"
                     /locus_tag="ROH59_001239"
     CDS             complement(51280..51606)
                     /gene="trpR"
                     /locus_tag="ROH59_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HDX4803753.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLED
                     VLLKSD"
     gene            complement(51696..53633)
                     /gene="sltY"
                     /locus_tag="ROH59_001240"
     CDS             complement(51696..53633)
                     /gene="sltY"
                     /locus_tag="ROH59_001240"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HDX4803754.1"
                     /translation="MEKAKHVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     QIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            53840..55507
                     /gene="ettA"
                     /locus_tag="ROH59_001241"
     CDS             53840..55507
                     /gene="ettA"
                     /locus_tag="ROH59_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HDX4803755.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDSLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            complement(55628..56860)
                     /gene="nadR"
                     /locus_tag="ROH59_001242"
     CDS             complement(55628..56860)
                     /gene="nadR"
                     /locus_tag="ROH59_001242"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418807.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HDX4803756.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRYLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIETVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQR"
     gene            complement(56881..58263)
                     /gene="radA"
                     /locus_tag="ROH59_001243"
     CDS             complement(56881..58263)
                     /gene="radA"
                     /locus_tag="ROH59_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDX4803757.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKTPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            complement(58312..59280)
                     /gene="serB"
                     /locus_tag="ROH59_001244"
     CDS             complement(58312..59280)
                     /gene="serB"
                     /locus_tag="ROH59_001244"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HDX4803758.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGERVAEVTERAMRGELDFTASLRS
                     RVATLKGADANILQQVRENLPLMSGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKTEVTIRHADLMGVFCILSGSLNQK"
     gene            59386..60030
                     /locus_tag="ROH59_001245"
     CDS             59386..60030
                     /locus_tag="ROH59_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HDX4803759.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVDVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            60058..61074
                     /gene="lplA"
                     /locus_tag="ROH59_001246"
     CDS             60058..61074
                     /gene="lplA"
                     /locus_tag="ROH59_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HDX4803760.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHI
                     TRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFQEQEKELRELSAWMA
                     GAVR"
     gene            complement(61075..62406)
                     /gene="yjjJ"
                     /locus_tag="ROH59_001247"
     CDS             complement(61075..62406)
                     /gene="yjjJ"
                     /locus_tag="ROH59_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HipA family toxin
                     YjjJ"
                     /protein_id="HDX4803761.1"
                     /translation="MSELTDLLLQGPRSAPELRQRLAISQATFSRLVARENRVIRFGK
                     ARATRYVLLRPYRGIERIPVWRVDDAGKAHKFADIRLCWPQGSCLVTGADGDEQWFDG
                     LPWYLTDLRPQGFLGRAWGRKLAAQLNLTDDIRLWQEEDVLYALTVFNGEYTGGWLVG
                     EGNYQRWITAQRPAEIPLDQKLTRYEQLASDALAGEIVGSSAGGEQPKFTCYAQTPSG
                     NKHVLVKFTVPQQTAVSQRWGDLLIAESIAAQILRDGGIHAIESTVLVTSNRQVFLEA
                     ERFDCKGNDGRLPIVSLEAVQSEFISSPGSWPEAMRHLCEQQLVTHQSVAQTEVIWAF
                     GRLIANSDMHAGNLSFYLSEPPFALTPVYDMLPMAYAPNSAGMLRDAAIEVKFDLNIS
                     KSAWLTAIPLAQQFWQTVARDPRISEAFRHIAQEMPEKIRQIEEKVTRMGG"
     gene            complement(62573..63292)
                     /gene="deoD"
                     /locus_tag="ROH59_001248"
     CDS             complement(62573..63292)
                     /gene="deoD"
                     /locus_tag="ROH59_001248"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDX4803762.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(63349..64572)
                     /gene="deoB"
                     /locus_tag="ROH59_001249"
     CDS             complement(63349..64572)
                     /gene="deoB"
                     /locus_tag="ROH59_001249"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDX4803763.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     HGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            complement(64624..65946)
                     /gene="deoA"
                     /locus_tag="ROH59_001250"
     CDS             complement(64624..65946)
                     /gene="deoA"
                     /locus_tag="ROH59_001250"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313368.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HDX4803764.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEHRNPRLFDVT
                     MALCVEMLISGKLAKNDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            complement(66024..66803)
                     /gene="deoC"
                     /locus_tag="ROH59_001251"
     CDS             complement(66024..66803)
                     /gene="deoC"
                     /locus_tag="ROH59_001251"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDX4803765.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            67061..68611
                     /locus_tag="ROH59_001252"
     CDS             67061..68611
                     /locus_tag="ROH59_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HDX4803766.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLAHGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDEIDIRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPDITPDDLLLEVAKNVCECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLIDPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            68583..69446
                     /locus_tag="ROH59_001253"
     CDS             68583..69446
                     /locus_tag="ROH59_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HDX4803767.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVPQCPHQALQIVDGKVVWNAVVCEQCDTCLKRCPQHATPMAQSMSVDEV
                     LSHVRKAVLFIEGITVSSGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPGQ
                     VDYLQHIEELAAFIKGLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VSRLIFPALYL"
BASE COUNT        16894 a        18634 c        17234 g        17009 t
ORIGIN      
        1 atattactcc gcctggcagt gcgcactgcg tgatgatgac atctacctga cggtaatgcc
       61 tgcatttcat atcgattgcc agtgtactgc ggcaatggcg gcattttctg ccggggccac
      121 ctttgtgctg gtcgagaaat acagcgtccg cgccttctgg gggcaggtac agaagtaccg
      181 tgccaccgtt accgaatgta ttccgatgat gatccgtacc ctgatggtac aaccaccttc
      241 tgtgaatgac aggcaacact gcctgcggga agtgatgttt tatctcaacc tgtcagagca
      301 ggaaaaagac gctttttgtg aacgcttcgg cgtccgcttg ctgacgtctt acgggatgac
      361 ggaaaccatt gttggcatta tcggcgatcg ccctggcgat aaacgacgct ggccgtcaat
      421 tggtcgggcg gggttttgct acgaagcgga gatccgcgac gatcacaatc gcccgctccc
      481 ggcaggtgaa atcggtgaaa tctgtattaa aggcgtacca gggaaaacca tcttcaaaga
      541 gtattttctc aacccgaaag ccactgcgaa agtgctggaa gccgatggct ggctacatac
      601 cggcgatacc ggataccgcg acgaagaggg ctttttttat ttcgtcgatc gccgctgcaa
      661 tatgatcaaa cgcggtggcg agaatgtctc ctgcgtggag ctcgaaaata tcatcgccac
      721 ccatcccaaa attcaggata tcgtggttgt gggtattaaa gattcgattc gcgatgaagc
      781 catcaaagca tttgtggtgc tgaatgaagg tgaaacattg agcgaagagg aatttttccg
      841 cttctgcgaa caaaatatgg cgaaatttaa agtgccctct tatctggaga tcagaaaaga
      901 tctgccacgt aattgctcgg ggaaaataat tagaaagaat ctgaaataaa tgaaacggca
      961 gggaactacc ctgtcagcta ataatcacgc tctaaaacaa tatgcatttt ttgcagggat
     1021 gttgtcgtcc ctgaaaaagc aaaaatggag aaaaggaatg agtgaatcat tacatctgac
     1081 ccgcaatgga tcaattctgg aaattaccct tgatcgtcca aaagcgaatg ctattgatgc
     1141 aaaaaccagc tttgaaatgg gcgaagtatt tctaaatttc cgtgacgatc cgcaattacg
     1201 tgtcgccatt attaccggtg ccggagagaa attcttttcc gcgggctggg atttaaaagc
     1261 ggcagcagaa ggcgaagcac cggatgctga ctttggcccg ggaggttttg cgggattaac
     1321 cgaaattttc aatctcgaca aaccggtcat cgccgctgtg aacggctatg cctttggcgg
     1381 cggctttgaa ctggcgctgg cggcagattt tattgtttgt gccgataacg ccagcttcgc
     1441 cctaccggaa gccaaactgg gcatcgttcc tgacagcggc ggcgtgctgc gtctgccgaa
     1501 gatcctgccg cctgccatcg tcaatgaaat ggtgatgacc ggcagacgaa tgggcgcaga
     1561 agaggcgctg cgttgggggg tagtcaaccg cgtggttagc caggcggaac tgatggataa
     1621 cgcccgcgaa ctggcgcagc agctggttaa cagcgctccg ctggcgattg cggcgctgaa
     1681 agagatctac cgcaccacca gcgaaatgcc ggtagaagaa gcgtatcgct atattcgcag
     1741 cggcgtgttg aaacactatc catcggttct gcattcggaa gatgccattg aagggccgct
     1801 ggcgtttgcc gagaagcgcg atccagtgtg gaaaggacgt taacaaccgt gagctattac
     1861 gcctttgagg ggttaattcc ggttgttcac ccgacggcgt ttgtccatcc cagtgcagta
     1921 ttgattggcg atgtgattgt gggagccggt gtctacatcg gcccactcgc ctcactgcgt
     1981 ggtgactacg ggcggttgat cgtgctagcg ggagccaata ttcaggatgg ctgcattatg
     2041 catggctact gcgacactga caccatcgtt ggggaaaacg gtcatatcgg gcacggagcg
     2101 atcctgcatg gttgtgtgat tggtcgcgat gcactggtcg ggatgaacag cgtgattatg
     2161 gatggcgcgg tcattggcga agagagcatt gttgccgcta tgagctttgt caaagcgggc
     2221 tttcgcggcg agaaacgcca gttgttgatg ggtacgccag cccgcgctgt acgcagcgtg
     2281 agtgacgacg agttacactg gaaacggttg aataccaaag agtatcagga tcttgtcggg
     2341 cgctgtcatg catcgttaca tgaaacgcag ccactgaggc aaatggagga aaatcgcccc
     2401 cgtttgcagg ggacgacgga tgtgacgccg aaacggtgat cttgccggat gcggcgtaaa
     2461 cgccttatcc gacctggctg gaaagcaacc gtaggccgga taagatgcgc cagcatcgca
     2521 tccggcaacc aggctgcgtg gtatcaacga aatgacatta acgacgcata ctctttgaca
     2581 acatcatctg ccacttctgc tcgcggttaa gttccgtgag cggaacggca ggaatacgcg
     2641 gcgtctttct tacgccgact aatttatccc ggctgttatt gcgcagacgc gcgtaaattt
     2701 gctcatcgat atcaaccact ttaaccagtc gctgacactg gcatccccgc ccttccagct
     2761 tattagggat catcttaact tcgcagctta tttctgtgac ttccgacaga atataagtca
     2821 gggtattaac cgccttgctg tgttcaatat cgaaatgaat agagatctct cttgctatca
     2881 cccaccgatt ttcagccatc atccattcgg cgattaacaa gtagagtggt ttttcaacat
     2941 atccttcaca catacgaact ccagtttcac aaattaaaag actggctatg actcgttttg
     3001 cagcaattaa acaaggccat attaaaattg tggatatatc gatagtatgc aacttcaccg
     3061 tcgataagtg tgagctaaat cctgcttatg tcatcaaaaa tatcgattcc ccaaaagatt
     3121 tacttaatgg gcaaaaaaaa cggtcctcat cagagaaccg tattagttat ttgatcaaat
     3181 tagcggatga aaaatatccg ccatgacacg ctattatttg atctgcgcgt gcatttcctg
     3241 caccgaaatt actttttcgg tcgcatcggc attcagcgcc atcgcggtgg caaagccgcc
     3301 gttcagggtg gtgtcgtaat gcactttata ttgcagcgca ctgcgacgga tcacgcggga
     3361 gtcttcaatc gcacgacgac ctgaggtggt gttgatgatg taggtatatt cgccattctt
     3421 aatacggtcc tgaatgtgcg gacggccttc atgcaccttg ttcaccagac gcggattgat
     3481 acccgcttcg cccagcacaa tcgccgtgcc gtgagtcgca tccagctcga agccctgttt
     3541 cagcagtttt gccgccaggt ccaccacgcg ttctttatcg ccttcgcgca cggaaagcag
     3601 cgcacgaccg tgtttcttca tggtggagtt gctgcccagc tgcgctttgg caaacgcttc
     3661 agcgaaggtg cggcccacgc ccatgacttc cccggtagag cgcatttctg gccctaacag
     3721 cgggtcaacg cccgggaatt tattgaacgg cagcaccact tctttcaccg agtagtacgg
     3781 cgggataact tctttggtta cgccctgctc agccagcgat ttgccagcca tcacacgcgc
     3841 cgccactttt gccagcggta cgccggtggc tttggagacg aacggaacgg tacgcgccgc
     3901 acgcgggtta acttcaatca ggtagacttc gttgtttttc accgcaaact gcacgttcat
     3961 caggccgcgc acctgcagtt cgaaggccag tttctgcacc tgctggcgca tcacatcctg
     4021 aatttcctga cttaaggtgt aggctggcag tgaacatgcg gagtcaccgg agtgcacacc
     4081 cgcctgctca atatgctcca tgatgccgcc aatcagcacc atttcgccgt cgcagatggc
     4141 atccacgtca acttctactg cgtcatcaag gaagtggtcc agcaacactg gcgcatcgtt
     4201 agatacgctg accgctgtct ggaagtagcg acgcaggtca gcttcgtcat agacgatttc
     4261 catcgcccga ccgccgagaa cgtaagacgg acgcaccacc agcgggtagc caatctcttt
     4321 cgctttctca accgccattt cgatggtggt aacggtggcg ttcgcaggtt gtttcagttt
     4381 cagacgctca accgcatgct ggaagcgttc acggtcttcc gcacggtcga tggcatccgg
     4441 gctggtaccg ataaccggta cgccagcagc ttccagcgcg cgcgccagtt tcagcggggt
     4501 ctgaccgccg tactggacga taacgccttt cggcttctca atacgcacaa tttccagcac
     4561 gtcttccagc gttaccggct cgaagtagag acggtcagag gtgtcgtagt cggtggagac
     4621 ggtttccggg ttacagttaa ccataatggt ttcataacca tcttcgcgca gcgccagcga
     4681 ggcgtgtaca cagcagtagt cgaattcgat accctgaccg atacggttcg ggccgccgcc
     4741 gagcaccatg attttttcac gatcggtgga cggattcgct tcgcactctt cttcataagt
     4801 ggagtacatg taagcggtgt cggtggcgaa ctctgccgca caggtatcca cgcgcttata
     4861 aaccgggtgc aagtcatact ggtcgcgcag cttgcggatt tctgcttcac gcacgcccgc
     4921 gagttttgcc agacgcgcat cggcaaagcc tttgcgtttc agctggcgca ggaattcagc
     4981 gttcaggcca gtgatgccca cttctgcgac tttctcttcc agacgcacca gctcttcaat
     5041 ctgtaccagg aaccagcggt caatgttggt caaattaaac acgccgtcta cagacaggcc
     5101 cgcgcggaag gcatcagcga tataccagat acgctctgcg cctgcatctt tcagttcgcg
     5161 gcggatttta gtcagcgctt ccgggtcgtc gagactcact ttcggatcga agccagttgc
     5221 gcccacttcc aggccgcgca gcgctttttg cagggattcc tgctgcgtgc gaccaatcgc
     5281 catcacttcg ccaaccgatt tcatctgagt ggtcagacgg tcgttagcac cggcgaattt
     5341 ctcgaagttg aagcgaggaa ttttagtaac cacatagtcg atggacggct cgaaggaggc
     5401 cggagtacgc ccaccggtga tgtcgttcat cagctcgtcg agggtgtaac ccaccgccag
     5461 tttcgccgcc actttggcaa tcgggaaacc agtggctttc gacgccagcg cagaggagcg
     5521 agacacgcgt gggttcattt cgataacaat caggcgaccg tttttcgggt tcaccgcaaa
     5581 ctggacgttg gaaccaccgg tttcaacgcc gatttcacgc agtaccgcca tcgaggcgtt
     5641 acgcatgatt tgatattctt tgtcggtcag cgtttgggct ggcgcgacag tgatggagtc
     5701 accggtgtgg atgcccatcg catcaaagtt ttcgatagag cagacgatga tacagttgtc
     5761 gtttttatca cgcaccactt ccatctcgta ctctttccag ccgatcagcg actcatcaat
     5821 cagcagctct ttagtcggag aaagatccag accgcgggcg caaatttctt caaactcttc
     5881 gcggttataa gcgataccgc cgccgctacc gcccatggta aaggatgggc gaataatgca
     5941 cgggaagcca acttcagcgg caaccgccag cgcttcttcc attgaatgag cgataccgga
     6001 acgcgcagtt tccagaccga ttttcttcat cgctacgtcg aaacggcggc ggtcttcggc
     6061 tttatcaatc gcatcggcag tggcaccaat catggtgacg ccgaactctt ccagcacgcc
     6121 ctgacgctca agctccagcg cacagttcag cgccgtctgc ccccccatgg ttggcagcac
     6181 cgcgtccggg cgctcttttt caataatctt gcgtaccact tcccagtgaa tcggctcgat
     6241 gtaggttgca tcagccattt ccgggtcggt catgatggtc gccgggttgg agttcaccag
     6301 aatgacgcgg taaccctctt cacgcagggc tttacacgct tgcgcgccag agtagtcaaa
     6361 ctcacacgcc tgaccgataa caatcgggcc cgcacccaga atcaggatac tttttatatc
     6421 tgtacgtttt ggcatggctc ttttactcct gattacttag cggttttacg gtactgctca
     6481 attaacgcga taaagtggtc aaacaacggc gcggcgtcgt gtggaccagg gctggcttcc
     6541 gggtgtccct ggaagctgaa cgccggttta tcggtacgat gaatgccctg taacgtaccg
     6601 tcgaacaggg atttatgtgt gacacgcagg tttgcaggta atgttgcttc atccaccgca
     6661 aaaccgtggt tctgggcggt gatcatcacc acatttttct caacatcttt aaccggatgg
     6721 ttgccgccgt ggtgaccaaa tttcattttg acagtcttcg caccgctcgc cagcgccagc
     6781 agctgatggc cgaggcagat gccgaatacc ggaatatcgg tttcgaggaa tttctggatg
     6841 gcggtaatgg cgtaatcgca cggggccggg tcgccaggac cgttggagag gaagatgccg
     6901 tctggattca ttttcagcac atcttccgca gaagtttgcg ccggaacgat ggtcagacga
     6961 cagcctctat ccaccagcat ccgcaggatg ttgcgcttgg caccaaaatc ataagccacg
     7021 acgtggtacg gcagctcgtc ttcttttttc gcttctggca gaccgccggt cagcgtccag
     7081 ctcccttgtg tccagctata gggttctgcg gtagtcactt cttttgccag atccatgcca
     7141 ttcaggccag ggaacgcgcg ggctttttct aacgccagcg ccgcatccgg gttatcgcct
     7201 gcgataatgc agccattctg tgcgcctttc tcgcgcagta aacgcgtcag cttacgggta
     7261 tcgatatcgg caatcgccac gatgttatgg cgcttcaggt aagaagagag gtcttcggta
     7321 ttacgaaagt tgctggcaat cagcggcagg tcgcgaatca ccagaccttg ggcatgtacc
     7381 tgagaagatt cttcatcggc gtcattagtg ccgacattgc caatatgggg ataagtaaga
     7441 gtaacgattt gacgagaata ggaaggatca gtgaggattt cttgataacc ggtcattgaa
     7501 gtattgaaaa cgacttcccc aaccgccgaa cctgttgccc ctatggcccg accgtgaaac
     7561 tgggttccgt cttccagaac caatagcgct gacttaatca aaacaccctc cagagaatat
     7621 tcactcactt tatttgcata ttaattcaca atgatgacgt aaatcaatgc aaatctgctt
     7681 accgacgaat ttctggcaaa cggcggcatt ctggagatat gggagctaaa agtcaactta
     7741 atggcgggat tttttatatt attttgtggc tcatgcatgt tttacaggca ttaagcgaca
     7801 aaaagatcat ataacatgtt ctggaaaacg cttgcgcagc aagaagattg catgaaatca
     7861 aaatgagtag aaaaaagtgg accaaatggt caaaatttac attaaaacaa caaaaacaga
     7921 atacaaaaca tgtaactttc agcatttgca ttaaatttaa aaacataaca ccaaaaataa
     7981 aagggccaaa aattaaagcc ctttatattc aatgaattaa atgtgttatt tttgcatcat
     8041 tataaatatt ttgtggttac agattattga gatcaagcac atctcgcata tcaaaaagac
     8101 cactttcctt accactcaac cacaaagccg atcttaccgc accgttagca aatgtcatgc
     8161 ggctggatgc cttatgggtg atctccagac gctcgccaat atcggcaaac atcgcggtat
     8221 gttcgccaac gatgtcacct gcacgcacgg tggcaaaacc aatggtgcca ggcacacgtt
     8281 caccggtatg gccttcacga ctgtagaccg cgcaatcttt cagatcttta tcaagagcgt
     8341 gggcgatcgc ctctcccatt gccagtgcgg tgcctgacgg cgcatcaact ttatgtctat
     8401 gatgtgcttc aataatttcg atatcggtgt agtcccccat cactttggct gctttctcca
     8461 gcagtttaag catgacgtta acgccaacgc taaaattggc ggcaaagaca atcgcaatat
     8521 cggcggcggc gtcacgaatc gcctgtttac cggcttcgtc aaaccccgta gtgccgatca
     8581 ccatcccttt gccatgctgg cgacaaaaag cgagatggtt cagcgtacct tccggacggg
     8641 taaaatcgat aaacacatca aaatcatctt ttatcgcatc aagactactt tgcacagtaa
     8701 cgcctgtttt cccggctccg gccagttcgc ccgcatcgct gcccagtaaa gaagatcctt
     8761 cgcgctccag cgccgcgccc agctgcacgc cttctaatgc cagcgccgct tgaatcaact
     8821 ggcggcccat acggcccccg gctcccgcga tggcaacgcg gatgtttgca tcatgcatag
     8881 ctattctctt ttgttaattt gcatagaccg ttttcagagt aaccagcgca tcgctacgcc
     8941 gccagccaaa aacgctgata attagaaatt aatgataaac agggagggat atcagtgaaa
     9001 ggcatgacgc agaaagtgat gcgtcatacc ctctggcatt atgcctggtc ttgtgacttt
     9061 gacggcaggc agcacagtat aagcagaatt acgcccgtaa cagggatcaa cacgacaatg
     9121 gtaacccacc accctgaata tccgatatcg tgcatccttc tgacggctaa cgctatcgcc
     9181 ggtacggcaa aaatcaacgt taaaataaat gacgcgggca gcgcaaaaaa aatgaaaaca
     9241 ccatagtcat tgttaattgt taccgctaac caccaacata aaagcggaag cagacagata
     9301 acgccactac caatcataaa cgaccagaac tcgaagcgat tggaaacacc ttcataatta
     9361 aagatgtttt tccacccttc cagatacgct tctccatacg tcatagaaca cttccttgtt
     9421 ttattattag agcgccaggg ccagcacctc agccacccac tgctggaagc ctttcacatc
     9481 cagatccagc gccacctgta cattggctgg tttgcccagg caaccgtcga tatcaacaac
     9541 cgtcgtgcct gaggtaaatt caccctgagt ttctaccgcg acaaaacacg gtttgagtgt
     9601 gaacaattcc gggcgcacca gccaggcgat agcgcaaaga tcgtgcatac gtagtccact
     9661 ttgcatactg ccgctacggt agtggctaaa cagggcgtgt agcatttttc cggtgcgatt
     9721 caactccggc aaagtagcga gatagtcagg ggttaatatt gcctgattgg tgacatccag
     9781 accgcacatg acgatttcga tgccgctacg gaagacacag gctgccgctt ctggatcggc
     9841 agcgatatta aactcggcgt ttggtgtgca gttgccgcga ccagcagaac cgcccatgat
     9901 caccagacgg cgaatatacg gcttacattc cgggcattgt gaaagtaaca gcgcaatatt
     9961 ggttaacgga ccgatagcca ccagggtaac gggctctggc gcacgcatca gggcatcacg
    10021 aattgccaga aacgccggta tacccagtgg ctgacggttg tgttcaacaa agttatagcc
    10081 agccattccc gattcaccgt gtacagatgc cgcatcgcgc ggcgcacgaa ccagtggtac
    10141 ggcagcgccc tgggcaagcg gaatatccac attccagaaa tgcagcagtt gcagggcgtt
    10201 gcgggtggtt ttctctaccg aaacattacc cgcgactgtg gtcatcagtt gcagatcgag
    10261 ttcgggggta aaaatcgcgg cggcaatggc aacggcatcg tcaatgccgg ggtctgtatc
    10321 gaggaagata ggtaaatgca tgttttctcc ataaaaaatg ccggtaacaa gaccggcatt
    10381 ttcgcataac ttagactact aatgacttaa tcgacttcac gaatatcgac acgcagctct
    10441 ttcggcactt cgaagacgat attttcttcg cggccttcca gcggaatggc ttcgccaccg
    10501 ccaagctgct gcaagcgtgc caccacattc tgcaccagaa tatccggagc cgatgcgccc
    10561 gcagtcacgc cgacgcattt aacctctttc acccactctt cctggatatc tttcgcatcg
    10621 tcaatcaaaa atgcgcgttt gcccatacgc tgggccagtt ccgccagacg gttggagttg
    10681 gaggagtttt tcgaaccaac caccagtact acttccgcct gctctgccag ggcgcgtacc
    10741 gcttcctgac ggttagtcgt ggcgtagcag atgtcatctt tgcgcggacc gacaattttc
    10801 gggaagcgtt tacgcagcgc gtcgatcaca tcagacgtgt catccaccga cagcgtggtt
    10861 tgggtcataa aggagagctt ctcttcattt ttgaccgtca gtttccacac atcgtctggc
    10921 gattcgacca gatacattcc cccttccggg ttgctgtact ggcccatcgt cccttccact
    10981 tccgggtgcc cggcgtgacc gatgagaata gattcttcac cacgacggct ggcgcgggcg
    11041 acttccatat gcactttggt caccagcgga caggtggcat caaacaccgt caaatcgcgg
    11101 cttttcgctt cgttacgtac tgcctgagaa acaccgtgtg cggagaaaat caggatcgcg
    11161 ccgtccggta cttcgctaat ctgctcaata aagatagccc cacgctcgcg caggctatcg
    11221 accacgtagc ggttatgcac cacttcgtga cggacatata tcggtgcgcc gtaaatggcc
    11281 agcgcgtttt caacaatgct gatagcgcgg tctaccccgg cacaaaaacc acgcgggttg
    11341 gccaacagga tctgcatgtt acgcctccag tgccggatcg atttccagca cttcaatatc
    11401 aaaatgaacg gtctgcccgg ccagcggatg gttgaaatca acggtaatgg agtcgccgtt
    11461 aatttcgcgg atcacgccag gcatctcact gccatccatt gcggtaaaaa gcatgattgc
    11521 gccaatttct ggctcgcctg catccataaa ttcacggcgg gagaagtact gaatcaggtc
    11581 cggtgacggc acgccaaacg ccgcatctgg ctccagcgag aaggtggttt tatcgcccac
    11641 tttcagcccc agcaggtgtt gctccagccc ttcagaaaga gaagcatcac ccaggcggaa
    11701 cagcgccggt ttaccgttgt tgcgggtaga ctcagcggtg gtgccatcat cgagtttcag
    11761 cgtgaagtgc accaggacgg cgctattgct ctgtacagat tcagacatgc aggtttgctc
    11821 ttatattttg aggatttttg ccggatgcgg cctacgattt cgcagcaatc tgtaggccgg
    11881 ataagatgcg tcagcatcgc atccggcagg gtttattatt gttttttcgc tttagaaggt
    11941 aaaaaacctt ccagcacaat cagtgccgca ccgacacaaa tggcagtatc ggcaaggttg
    12001 aaggtggcga agtgccagtc gccgacgtag aagtcgatca tatcgacaac gaagccgtgc
    12061 cacaggcggt cgaacaggtt gcccagcgcg ccgccaataa tcagcgcgta agcgatattg
    12121 tttagcttct gcgcggcctt cgagcgatac atcatcacta ccaggatcac gctaatacca
    12181 atcgcaatac cggcaaagaa ccaacgctgc cagccgccgc tatcggcaag gaaactaaac
    12241 gccgcgccat agttacgcgc ataatgcaga ttaagcgacg ggaacagcgg gaccgtatcc
    12301 cccagagcaa agttctggag gatcaggtat ttgctgccca gatcgataat cagcacgact
    12361 accaccagcc acagccagcg tagccctgtt gaacagatcg attgactcat caggcaaact
    12421 tacgtttttc accgtcaccg gcgacgttgc tgacacagcg gccgcagatt tctgcgtgtt
    12481 ccgccacctt gccgacatcc tgggtgtagt gccagcagcg agggcacttc tcaccttcgg
    12541 ctttactcaa cgcgactttc agccctttga ggacttcgct ctgctgggca tcagcaggtg
    12601 cgtcgttata gtctgcaacg gtagcgccgg aggtcaacag gacaaatcgt aattcatcgc
    12661 ccagcgcggt cagtttcgcc gccagttccg gttctgcata caaggttact gcagcttcca
    12721 gcgagccgcc cactttctta tcggcacgcg cttgctcaat gactttgttc acttcgccac
    12781 gcactttcaa cagctcgtcc cagaacgcat cgttcattgc ttcactgtct gccagaccaa
    12841 acaggccttc gtaccactcg ccggtgaaga cgtatttttc acgttcgccc ggcaggtagc
    12901 cccacacttc atcagcggtg aaggagagga ttggtgccat ccagcgaacc agcgcttctg
    12961 cgatgtgata cagcgcagtc tggcagctac gacgcgccac gctgtccgct ttggcggtat
    13021 actgacggtc tttgatgatg tcgaggtaga aggaacccat ctcaacggag cagaagcgca
    13081 tcagacgctg taccacttcg tggaaatcgt atgcttcgta cgccttgagg atgtcttcct
    13141 gtgccgcttt cgcacaacct acggcccagc gatccagtac caccatctct tccggtttca
    13201 ccatatcttt tgccggatca aaaccgttca ggtttgccag caggaagcgc gcggtgttac
    13261 ggatacgacg atagctgtcg gcagcacgtt tcagaatctc gtcagaaaca gccatttcgc
    13321 cggtgtagtc ggttgatgcc acccacagac gcagaatatc cgcacccagt ttgttcatca
    13381 catcctgcgg cgaaacggtg ttaccgatgg atttagacat cttgcgaccc tgaccatcca
    13441 cggtaaagcc gtgagtcagt acctgacgat atggcgcttt gcccttcatc gcggtagaga
    13501 tcatcaggga agacatgaac cagccacggt gttggtcaga accttccaga tacatgtccg
    13561 ctgcgtgacc ggcaaattcc ggacgcacat caacaacgga agagtgggta gatccggagt
    13621 caaaccatac atccagcgta tccggtactt tcacatactg gtcagcttcg tcgccgagga
    13681 tctctttcgc atcgagatcc caccacgcct ggatgccgtc aacttcaacg cgttttgcca
    13741 cttcttccat cagttcgaga gtacgcggat gcagttcttc tgtgtctttg tgcacgaaca
    13801 gtgacatcgg cacgccccag gtacgctgac gagagataca ccagtcagga cggttagcaa
    13861 ccatcgactc gatacgcgcc tggccccagt cagggatcca ctgcacgcct ttgatctctt
    13921 tcagtgactg cgcacgcaga cctttctgat ccatgctgac gaaccactgc ggcgtcgcgc
    13981 ggaagatgat cggcgtttta tgacgccagc agcacggata gctgtgttgc attttctcaa
    14041 cgtgcaacag tgcgcctttt tcctgcaaca acgcaatgac aatatcgttc gctttgaaga
    14101 cgttaacgcc atccagagtc gggtaagtac ccggcagata agtgccgtcc gggccaaccg
    14161 ggttagcggt ttccagacca tatttttgac cgatcacata gtcgtccgga ccgtggcctg
    14221 gcgcggtatg aacggcaccg gtaccggcat ccagcgtaac gtggtcgcca agaattgccg
    14281 gaacatcgaa gtccataaac ggatgggtaa agcgcaacag ttccagctca gcacctttca
    14341 ccgtgccaag aatggtgtaa tcgctaacgc cgatacgctg cattacgctt tcaaccagat
    14401 ctttcgccag aatcacggcc tgaccgtcga tttgcaccag cgcataatca aaatcaggtg
    14461 caatggagat tgcgcggtta gcaggcagcg tccacggcgt ggtggtccat ataaccagcg
    14521 aaattgggcc gttaacattg cttacgccaa atttcgtttt cagcgcatcc tgatcgaccg
    14581 cctggaaagc gacgtcgatg gacggagaag ttttgtcgta atactcaact tccgcttctg
    14641 ccagtgcaga acggcagtca acgcaccagt gcaccggctt cgcgcctttg tgcaggtgac
    14701 cgttgccgat gattttgccc agcgcgcgga tgatgttggc ttcagttttg aagtccatgg
    14761 tcaggtacgg gtgcgaccag tcgcccagca cgcccagacg gataaagtct ttgcgctgac
    14821 cgtcaacctg ggtcgcagcg tattcgcggc acttggcgcg gaactcagcg gcggtgaatt
    14881 tctcccccgg cttaccgtat tcttgctcta ctttcagttc gattggcaga ccatgacagt
    14941 cccagccagg cacatacggc gagtcatatc cagaaagccc tttggactta atgataatgt
    15001 ctttcagaat cttgttaacc gagtgaccaa tatgaatgct gccattcgca taaggagggc
    15061 catcatgcag aatgaaggtt tttttgcctt ttttagctgc acgaatgatg ccgtacagat
    15121 catcatcagt ccaacgcgcc agcattcccg gttcgcgctt ggcgagatcg ccacgcatcg
    15181 ggaaccctgt ttccggcaaa ttcagggttg atttatagtc actcatcaga ttctcggttc
    15241 cgtatttcgg tttgattaca taacaggctt aagccggttt tgttagccca aaaaattcgc
    15301 gggcggttaa ttcatcacgc gcaatctgcg ctttcagttc gtccagcgat gcaaatcgct
    15361 gctcattgcg tattttttta cgcagcacta cttgtatatg gcgaccataa aggtccattg
    15421 caacatctaa caaatgcact tccagttgct ggcgaatacc ggcaaccgtt gggcgtgttc
    15481 cgatgtttgc aacgccgggt aacggctttt cgccaaggcc caacacttct accgcataaa
    15541 cccctttcac cggggaaacc tgacggcgta gcggtacatt cgccgtcggg aaacctatag
    15601 tgcgccctaa ttcatcaccg tggactacac gcccggagat ggcaaacggg tgccccagta
    15661 aactttctgc cagagccaga ttgtcatccg ccagcgcctg acgcacggcg gtgctgctga
    15721 tacgcacgcc accttcgcaa aaagtttgcg tgctggtgat atcgaagccg tattccatac
    15781 ccgctttctg taataacaag aaatcgcctt cacgaccagc gccaaagcgg aaatcgtcac
    15841 ctacggcaag aaattttacc cgcaagtgct tcaccagaag atcactgatg aagttttgcg
    15901 cggttaacgc cgcaaaacgc ctgtcaaaac gcacgcacag cacgtaatca acgccacact
    15961 ctgcaagata acgcagtttt tcccgcagcc gggtcagccg tgccggggct ttatcagtag
    16021 caaacagttc cagtggttga ggttcaaaaa gcatcaccat caccggtaag ttgcgcttgc
    16081 gcccttcttc ctgcaagccc tgtaacagcg cgcgatgacc gcgatgcacg ccgtcgaaat
    16141 taccaatagt cagcacacac ccttcttgcg gggcctggct gagattatgt atgccgcgta
    16201 tcagcttcat gtctggctca aaacagtgaa aatcgtccga gtataccttg tacagcggtc
    16261 aaggttaacc ggcgattgag taccgaaatc agaaagaagt ggcttttcat tgctatggcg
    16321 caaatcatgg gaagaaactg accgcctact gcaatttttc tcgcggaaaa gctgtattca
    16381 caccccgcaa gctggtagaa tcctgcgcca tcactacgta acgagtgccg gcacattaac
    16441 ggcgcttatt tgcacaaatc cattgacaaa agaaggctaa aagggcatat tcctcggcct
    16501 ttgaattgtc catatagaac acatttggga gttggacctt ggctaatatc aaatcagcta
    16561 agaagcgcgc cattcagtct gaaaaggctc gtaagcacaa cgcaagccgt cgctctatga
    16621 tgcgtacttt catcaagaaa gtatacgcag ctatcgaagc tggcgacaaa gctgctgcac
    16681 agaaagcatt taacgaaatg caaccaatcg tggaccgtca ggctgctaaa ggtctgatcc
    16741 acaaaaacaa agctgcacgt cataaggcta acctgactgc acagatcaac aaactggctt
    16801 aattgcctgt tgttgtcagc tttgtaaaaa aacccgctct ggcgggtttt tttatgcctg
    16861 cggaagttac cgttaatcga ttatatattt tctccatgaa tacatcataa atataattga
    16921 tgctttttca ttgtgaaaga taaaatattt catttggctg taaaacgtga actgtataac
    16981 aaatagcagg aaaactgaat aaaaaactaa ttaacgcaac cttaaaacga aaaattataa
    17041 ttgtcgctct tccccacttt aattactctc attgccacaa cgttgcttta catcattaat
    17101 aaatacgcat caaggatagt tagcatgtat ttgcttagaa agtaaaagtc gtttttctga
    17161 gccaggcatt cttgttctgg agagaatata atgagttccg tacttgaaac tgataaatca
    17221 tccgcatccg attcactgcc tttaatacaa cggatcagct atggttcgct ggatgttgca
    17281 ggtaatctgc tctactgttt tggctccacc tacattctct atttctacac tgacgtggcg
    17341 ggcataagcc ttgccgtagc tggcatcatc ctgctactgg cgcgtattgt agacggtatc
    17401 gatgccccgg tatgggggat tattattgat aaaacgcatt cccgctacgg taaatgtcgg
    17461 ccgtggtttt tatggttgcc attacctttt gctgtattta gcgcactctc attctggtcg
    17521 ccagatatca gtatgacagg taaaaccata tattcagcaa tatcgtacat gttagccagc
    17581 attcttttta ccggtttaaa cacgccgcta agcgcaatat tacctttgat gacgttatca
    17641 ccaaaagaac ggttggtatt aaactcttac cggatgaccg gcgggcaaat tggcgtgtta
    17701 ttaatgaatg cgacggcgct accgttagtg gcttttcttg gaaacggtaa tgataaggca
    17761 ggatttattt atactgctat cgtcttttcc gtaatctcct gtgcgctaac gctatttgcc
    17821 ttcaaaaata ttcgagaact ggataccgac aaaatacagc aggaaccacg tctgccgatg
    17881 aaaaagagct tttcggcaat gaaaggcaac tggccgtgga tcctgatggt gctggcaaat
    17941 ctcatcttct ggattgcctt acagcagcgc aacacaacca ttgtttacta tttaacctac
    18001 aacctggatc gcaaagattt agttcccttg atcaacagcc tcgccaccat tcagattttg
    18061 tttatcatcg caattccgtt tttcagccgt tacctctcca aaacctggat ttggatcacc
    18121 ggcctgctgg tcgccatgtt cggcggagga ctgatgtggc tggctggaga caatattcct
    18181 ttgatgattg ccgcctggat gctggcgaat attggcagtg gcattgcctg ctctatgccc
    18241 ttcgccatgc ttggtttcgc ggttgatttt ggtcgctgga aaacagggat taaagctacc
    18301 ggcattctaa tcgccttcgg cagtaccttc tgcatcaaga tgggcagtgg tatcggcacc
    18361 gccttcgccg cctggattat gaacagcttt ggctatattc ccaaccagcc acaaactgcc
    18421 gccggtctgg acggtattag ctgggcgttt atctgggtgc cagccgtgct ctttgcactc
    18481 gccgccattc cactgctctt ctttcgtaaa tatgaagcga tggaagagtg catccaacac
    18541 gatttgcaag ttcataaccc ttaaacatgt cacaagctcc tggaggaaat tatgtcgttt
    18601 attaagcaag atccccatcg tctggtctgg caacaagacg atcgttatct ctggattgaa
    18661 gcatggggtg agaacagttt acgtgtgcgt agcggtcgcc atctgccgat gatgcgcaat
    18721 gaaaactggg cattaacaga agaaaaaggt gatgctgtcg cctatatcac atatgaagaa
    18781 aagcaggcaa cactacaaaa cggcaaaatc accgccattg ttaatctgca gggtcagatc
    18841 tctttctggc gtaatgcaga aaaatgcctg ctgcaggagt tctggcgtca gcgcggcgaa
    18901 attggcgaag atgagtcggc ccacggtcag tatgtcagcg ccctgaattt acaggcccgc
    18961 gagttcaaac cgattcccgg cgggaaatac acaatcaagg cgcggttcga agccaacgat
    19021 ggcgaaaagt tgtttggcat ggggcagtac cagcagccaa atctggattt aaaaggctgt
    19081 atgctagagc tggcgcagcg taattctcag gcatcggttc ccttcctgct ttctaatcgc
    19141 ggctatggtt ttctgtggaa taacccagcg gtgggtcgcg tcactttcgc gcaaaatggc
    19201 acggaatggg tggcagaagt tagcgaacag ttggactact gggttaccgc aggggatact
    19261 cccgcagaaa tcagcgccgc ctatgcacgt gttaccggta cgccgccaat gatgcccgat
    19321 tacgccatgg gattctggca gtgcaagttg cgctaccgta atcagcaaga gttactagaa
    19381 gttgcacgtg gctacaagca gcgtaatttg cctatttcgg tgattgtcat cgatttcttc
    19441 cattggccga atcagggtga ctggatgttc gatctgcgcg actggcccga tcccgatgcc
    19501 atgattgccg aactaaaaga gatgggcatt gaactgatgg tctccttctg gcccacggtt
    19561 gataaccgta ccgagagtta tcgggagatg aaagaaaacg gctggctggt ccacaccgag
    19621 cgtggtttgc ctatcaatat ggatttcctt ggcaacacca cgttctttga tgctacccat
    19681 cctggcgcac gggaatatgt ctggaacaaa gccaaacgca attattacga taaaggcgtg
    19741 aaactgttct ggctggatga agccgagcca gagttcggtg tttacgatta tgacaactat
    19801 cgttactacg cagggcctgt gctggaagtc ggtaatatct atccgcgtat gtacgccaaa
    19861 acgttcttcg atggtatgac cgcggctggt gaaaagcagg tgattaacct gctgcgctgt
    19921 gcctgggctg gcagtcagaa atatggcgct ctggtgtggt caggcgatat tcactcctct
    19981 ttccgttctt tgcgtaatca gtttgccgct ggcttgaaca tgggaattgc cgggatcccg
    20041 tggtggacaa ccgatattgg tggtttccac ggcggtaata ttcacgatcc gaaattccat
    20101 gaactgttaa ttcgctggtt ccagtggggg gtattcagcc cagtaatgcg tttacatggc
    20161 aaccgcgacc cgcaggtttt gcctgaacaa ccctatcgtg atggcatagc acaatgtccg
    20221 actggcgcgc cgaatgaagt ctggagctat ggtgaagaaa ccggtgaaat tctcacttcc
    20281 tgcctgcagt tgcgtgaaaa actgaaatct tatatcagta aaattatggc tgagacgcac
    20341 gagaagaaca gcccgataat gcgcacgatg ttctttgaat ttcctgacca ggcagaaagc
    20401 tggaatattt atgatcagta ctgctttggc ccagaccttc tcgttgcccc tgtaatgcac
    20461 gaaggtacac gttcacgtga tgtctggttg cctgctggag agacatggat cgatttttat
    20521 acccatgaac actacgcggg tgggcaaacg cttcatcatt gcgcaccgct gcaccagata
    20581 ccggtattca ttcgcgagaa agggaaatat cgccagatat ttcccgttta aaggacatcg
    20641 tttgttcatt agcacgcccc gtatgtagcg gggcgtgagt tttaatagct atcgtgaggc
    20701 gggagaaaac aacgaagaat aatccgtatt gcagattcgc tgtaccgccg ggtgctgaat
    20761 catccgctca gcaaaaatag catggtactc ttccatcaca ttctcgacgc gaccaatttc
    20821 tacgacagtt ttatcggcat aaaagtcata tgcataaagc gttggagcaa cgaagattgc
    20881 attgtgcatc gcaccaaaag ctttcatcaa cgcggcatca tcaaactcgc caaggatttc
    20941 tacgtttaat ccctgggagt taaaccagtt aagcaatttg cgccctaaca ttgaacgtcg
    21001 cccaggaatc aaaagccgcc gttcttccag acaagccggg aacggttttt ccggtggtgg
    21061 atttgtacac cagaaactca cgccacattc gccaattctc acggagaaca ggccttcctg
    21121 ctgcgtagaa tctatcggac agtcggaaat gatcatatcc agtttatgct gacttaattg
    21181 ctccagcagc atttcgtggg tggattcgaa gcagcgaaga tgaatcggct cgccttctac
    21241 cactgcggcg ttaagtacgc tactgaccag acgtttggaa agtgcatctg ccacaccaac
    21301 atcaaacaat aagttggact ctttgcgata gttgacgata tccagcattt cctggcttaa
    21361 ggtgaacatt ttatcggcat agcgatagac cagttccccc agttcgctgg gttccagacc
    21421 acgtccttta cgcttaaata gtttcccttg caggcgctct tccagcgccc ggatctgccc
    21481 ggtaatggtt tgtggtgtta aataaagcgc ctccgctgcg ccaaccacag aaccttcttt
    21541 gtagacatgc cagaagtaat acaagtggtt gtaattgata tgagacatgc tcatttctct
    21601 ccctgataac aatgaaaagg gagccgttta tggctcccca gtacatcgtc ctgtcaaact
    21661 gatggacgta aacgaacgcg taaccagcta tatccaatta ccgccgaaga aattgaaccg
    21721 acaaggatac ctaattttgc ccagttaatc agttctggat ctacgctacc aaatgccagg
    21781 ctggcaataa agatagacat agtaaaaccg ataccgcaca ggataccaac cgccataatt
    21841 tgctggtaag tcgttccctc tggcagatgt gccagtttca aacgcagcgc caaccagcag
    21901 aacagactaa tacccagtgg cttgccaatc agcaaaccag cgatgatccc taatggcaga
    21961 atggaggtca aaccttccag cgtgacacct tgcagtgaaa cgccagcatt agcaaatgca
    22021 aacagcggca aaatcagata cgccacccat ggatgcaaaa catgctccag acgtttagcc
    22081 ggagagcgcc catgcttctc ttttaacgga ataaagaagc cgacaatgac gccagccagc
    22141 gttgcatgga cacctgattt caacaccgct gtccacagca ccacgccaac cagaatataa
    22201 acgcccgtgc ggcgtacacc acacagattc aataccgcga gtaccgcaat tgctacagcc
    22261 gcgacgccaa gagaggccat cgataagtca ttagtgtaga acaatgcgat gataatgatg
    22321 gccccaagat cgtcgataat agccagagcc atcaaaaaga tcttcagcgc taacggaaca
    22381 cgacttccca acagcgccaa cacaccaagt gcaaaggcaa tgtcagtcgc cgccgggatt
    22441 gcccagcctt cgcgagtgat aggatcggca tagttaaaag ccagatagag caatgccggg
    22501 acaatcatcc cgccgattgc ggcaataaca ggaaatgccg cctggcgcag actggccagc
    22561 gaaccttgca tcagctcgcg tttaacttcc agaccaacca acaggaaaaa taccgccatc
    22621 agagcgtcat tgatccatag cagcatgttc ttgttgatct caagtgtccc aacccggagc
    22681 tgaaccggcg tctcaagaaa gtcgtgatac catccactgg ttgcaccgct gttggccata
    22741 atcatcgcta atacagcggc aataatgaga ataatgcctc ccgaggcatc actgctaaag
    22801 aatcgatgca gatgtttcac tttttatttc tcttcaggtg aatagatcgt tttcacgatt
    22861 ttaccccgca cgaatcatcg ttaaaatcag attatagtgt aggaatagct cgctttttac
    22921 gatctattaa aagaattgcg ccatcagcga gagatgagtt tttgatgccc gaaagcggcg
    22981 gctgatgacc ttaaacccca ttaatcatag tctaatgtca agatttctga agaaattatt
    23041 cggaaaagta ataattaaat tgttccatgc tctagttttt tattccacag atgtttgagg
    23101 atatctaatg tagaaacgac attcgcagga gacattcggt tcaatgatat aaggaaagga
    23161 tggttctcca caaagtggat aaaacgcgtc gcactgttca atgttgcatg ccgcatctcg
    23221 cggactttct tactgccagt gagattgcat acagccattg aataattgcg gttagaaaat
    23281 gcacgccaga cattatttcg taccccacca ctaaggaata atcgcggcgg aaaatcaatg
    23341 gtggcgggtg ccacaccgcg ctctttgaca aaggaaatat ggcagcgacc ttgatgaata
    23401 tgctgcaaat tagccatcag gcagccgccc aatataaagc attcgtgatc aaggtaatgc
    23461 tgaacgttgt tggaatgctc atcggtcagt attctgacca gttcaaaatg acgatatgcc
    23521 ggaagaaccg gttttaccaa cattcccgga tcgttttgat gtaaaactgc cgggccgtaa
    23581 tcaatatcaa acaaggtatc ccgccgcata gtaagtaact ctttgcgctg gacatgatgt
    23641 gccagcgtcc ctggagacat acgctcttca tagttcgatg tgtattgata atgttgctct
    23701 acggcagatg gggagtaatt ggttgagatg gcaaccaccc tgccgctttg ttcttctgcg
    23761 gtaacaagag cataaagaga gttattgcta ccattatact tgacgcgaaa agcgcgggta
    23821 ctcagggtaa tatcagaagc tgggaaacac tgtcgacttt ctttatagtt tgcttcacgc
    23881 gctaatttta acagttcacg gctaagtcca gtgctgttaa gaagtaatga ctttctgata
    23941 tccgcaagtg cctccccttg ctcaatcatc aatgctaact gggctcctcg tggtgtggta
    24001 attacatgtt ccagagtgat aaatgttttc tcacaatgat ggcaatacat tcttctctgg
    24061 ccttgtgcag aatatccata ttttttgagg gacgtgcctc cgcaagttga acattggcaa
    24121 atcaaacctc tccaggagtg attcacaata ttacgataaa tattaagcga ctgttcagat
    24181 atcactggaa acaagtaacc acattcacgg cataaaatat ttttaccctg tgcgacataa
    24241 tcctggctat tcagcaaccc caggttttta catcctggtg ttttgcaaca atcaacattt
    24301 acgttggtaa acatatccac tccctgcgaa tagccgtatc ttgatattgt tcaacgcgaa
    24361 aagaacctga ttcaatgcgt agcactgaat caggcgggca tagccctaaa tggcatacat
    24421 tacatttatt atgattatca ggttagcccc aggtcaccgc ttctggttta tcacctctgg
    24481 ctttcattag agaatcatta tcaatatcag ttttatattt taaaaactta ccatacatct
    24541 gtttttcaat atctggtttt ttaccgatca gattaagtgt ttcataacga tcagatttca
    24601 gattgtagag atatttcggt ttattattgc gatcgataat catcttccag tcaccatcac
    24661 ggatcgccca ttcatcggtt ggatcatcct ggaatggcat atcaatcccg aaaattaatg
    24721 gcttttcgcg tttcaatgct ttttgctcaa gaacaggaac cagcgattca ccatcgaaag
    24781 tacggtctgt aggtaatttg aagttcatca ttttcgctaa agtaggcatc cagtccagac
    24841 cataaacggg tgtatctgaa accattccct gtggtagatg tttaccatat ttaataatgg
    24901 ctggaacacg aattccgcct tcccaaaggt tatccttgcg accgcgtaat ccatccgttt
    24961 cccctgccaa attcagctca tacactttgc gcgcttcacg cgttaccgga ccgttatcac
    25021 tggtaaaaat aacgattgtg ttatcttctt cacccacagc tttgatttta tccagcactt
    25081 ttccaacctg tgcatccaga tagctgatat tggcataata ttcccccaca ccacgccagg
    25141 gtttgtctgc ccagtcgcca taaaataaat caggatgctg cttctgatac gcgctcatat
    25201 attgtgagta catatcgagg tattttttgg gcgaagccag ggggctatgc acttcggtaa
    25261 aagcaacata gaggaagaaa ggcttgctgt cctttttgtt atccagccag ttgacgactt
    25321 ccgaactgac atactcaccg ctcattttat cggctcgtgg agtgggttgc ccgttacgta
    25381 gccagcctgt cgggtaaacc atgccataac gcgggcgttc tttagcgtta tccagcgtgg
    25441 cgtcggtaac aaagcccgcc gtattaacca gtgagtaatc aaagcccata tcttgtgctt
    25501 gtggctgatc ggtgcgatcg ctgcctgcat tcagatgcag cttacccatc attgccgtgt
    25561 cgtacccttg cgctttgagt agattagcaa tcgtgagttc gttacgccct aaggcaacat
    25621 ctttgcctga aggaatccat gagcgaattc cagtacgaaa tggcatccgg ccggttaata
    25681 gccctgcgcg tgaaggtgaa cttaaaggag cgggggcata gtagtcagta aatttgaccc
    25741 cttcctgggc aagcctgtcg atattaggtg ttttaacgat ctgatgacca tatgttgcta
    25801 aatcgccata acctaaatca tccgccataa taatgactaa attaggttgt ttagcctctg
    25861 cggctaaggc aggactaaaa gcattccctg tgcaaactgc aaggccgatc aaactggcca
    25921 ttaacgtttt ctgcataatt attccctgat aaaaaattag aaatcataac caagcatata
    25981 aatcatttga tcgccaaagc catcgtagcc cagcttatta tcgaaataac gccacgtcac
    26041 actggctttc cagcgaggat agaacttcca ggcaatagtt aaaccgccat ttaacccgtt
    26101 ccggccaaat tgctgctccg tgtaagcatc gttcctgtcc agttctattt cattccagtt
    26161 agataaaaca aatttttcgt caaataacgt aaatggtaat actgctgtcc agccaacaac
    26221 ataaccattc caaccattcg tttgaccata tttagctgat acgtagtcac cagattgatt
    26281 atgtaatcca atatacggtt taaaaaagcc ccactcgccg ttccagccga ggtaaccgaa
    26341 tccataaaac atgtccagat cgtcacccca tgagttatcc cattggccat aaattttgcc
    26401 aaagaatgtc atatcagagt caaagagtct gacatgcgtc attactgaaa ccgtatgatt
    26461 tcgccctgct acagcatgat tgagtacatt actttcataa aatgagtaaa attctgcttc
    26521 tttaaaattt accccaaaat ccgcagtcac tttccatact tcaccacggt gagtgtttac
    26581 aaatccacta ttccagtctg cataacccgc atttattgaa ccaaaggttc ctttatattc
    26641 taatgaagaa tatgcaggaa aatgatagat agctgttatc agggtacacg caataagaag
    26701 tcgtcttttg gcagacatat aatatgttct ccattcattg tttttatgat tccataggaa
    26761 ttaatacacc agacaattca tttttattaa gaatgaccag gccagtatat ttaaagatga
    26821 ctatcgaagc gtgatgaaga tcgcagatta cttttgcgaa cgggcggagg gatatcgtgt
    26881 ttcagaaaat gtgtctgttt taaatatcac cctttgattt ataggcattt ttcatgatga
    26941 acttagcatt ggctgctgaa cgtatttctt tgtctctcta tagtattaca ctaaccttta
    27001 ataattaatt tcctttagcc attcactttt gatagaggaa aacacctttt ttgtgaatcc
    27061 ctggatatat ttaagttaaa taaattgatg tattgaaata ttattccgca aaaatgcgag
    27121 gcgtcttcag aaaaagaatt gataaaacag aagtgaatta aaagcgcagt ataatagcgg
    27181 cgggtgcttg aggctgtctg tctcaggcat tggctgaacg gcagatagag aaaagccccg
    27241 agtgatattt taccatcaac ccgaggcccc ctatatgcag aacacatgta gagtgcctct
    27301 tactgaccga aaggtcaagg agaagagagc aatgaagcag cataaggcga tgattgtcgc
    27361 cctgatcgtc atctgtatca ccgccgtagt ggcggcgctg gtaacgagaa aagacctctg
    27421 tgaggttcac atccgaactg gccagacgga ggttgctgtt ttcacggctt acgaatccga
    27481 gtaagagcaa cggcggggag tgatccccgc cactttacag gtgctcgcat atcttcaacg
    27541 cacccttttt tttacctggc ctgcccacgg gcaggctttt ggggaggtta gcgagtcagg
    27601 tcgtcgaaaa acttcttcac accatcaaag aagctctttg agcgcgggct gttgtgctcg
    27661 ccggttgggc caccaaagct ttcttgcagc tcttgcagca gctgtttctg cttctcgttc
    27721 aggcctaccg gtgtttcgac gacaacgcgg cacagcaaat caccctgtgc gccgccgcgg
    27781 acagacttga cgcctttacc acgcatacgg aacagcttac cggtctgggt ttcgccagga
    27841 actttcagtt taacgcgacc atcaagggtc ggcacttcga tttcgccgcc cagcgccgcc
    27901 atagcgaagt tgatcgggac ttcgcaatac aggttgttgc cttcacgctc gaaaatcggg
    27961 tgctgtttaa cctgaacctg aacgtacagg tcgcctgccg gtgcgccgtg ttcgcccgct
    28021 tcaccttcgc ccgcaagacg gatgcggtct ccagtgtcca cccctgccgg gattttaacg
    28081 gacagcgttt tgctgcgctc aacacgacca tgaccatgac atttgttgca cggatctttg
    28141 atcagcgtac cgcggccctg acagtgtgga caggtctgct gcacggcaaa gaaaccctgg
    28201 cgcatctgca cctggccaga accatgacag gtcggacagg tctgcggctg tgtacctggt
    28261 tttgcaccgc taccgtggca aacgtcacac tcttccagag tcggaatgcg gatctctttg
    28321 gtcacgccac gtacagcttc ttcgagggtg agctccatgt tatagcgtaa atcagcaccg
    28381 cgcgccgcac gttgacgacc acgtccgccg ccaaaaatat cgccgaaaac gtcaccaaaa
    28441 atatcgctga agtctgcgcc gccgccaaaa ccgccgccgc ccatgccgcc ttgctcaaac
    28501 gcagcatgac catactgatc gtatgccgca cgtttttgcg agtcggtcag aacttcataa
    28561 gcttccttga tctctttaaa tttcgcctcg gcctctttgt caccctggtt acggtccggg
    28621 tggtatttca tggccaggcg tttgtaggcc tttttgattt cacgctcttc cgctgttttg
    28681 gaaacgccta aaatctcgta ataatcttgc ttagccatct tttttgattt gcccctagat
    28741 gaatgcacgg gcggagagga aattcccctt cgcccgtgtc agtataatta cccgtttata
    28801 gggcgattat tttttgtctt tgacttcttc aaattcagcg tcgacaacat cgtcatcttt
    28861 cgcgttgttt gcagaagcat cagcaccggc agtctgctgc tgggcatgtt gctgctgggc
    28921 gatttccatc agtttctggg aaacctgtgc cagttcctgc attttcgctt cgatagcggc
    28981 tttgtcttca cctttcagag cagtttccag tgcagtcagc gcagactcga tagcagtttt
    29041 gtcgtcagcc ggcagtttgt cgcctgcttc ttcaacctgc ttacgggtgc tgtgcagcag
    29101 atggtcgccc tggttgcgag tctgtaccag ctcttcaaac ttacggtcag cttcggcgtt
    29161 agcttctgcg tcgcgtacca ttttctggat ttcatcttcg ttcagaccag aagaagcctt
    29221 gatagtgatc ttctgctctt taccgctgtt tttgtctttc gcggaaacgt gcaggatacc
    29281 gtcagcatcg atatcgaagg taacttcgat ctgcggcatg ccgcgcggtg ccgggttgat
    29341 accatccagg ttgaactgac ccagagattt gttatcagcc gcacgtttac gttcaccctg
    29401 cagcacatgg atggttaccg cagactggtt gtcttcagcg gtagagaaca cctggctgtg
    29461 cttggtcggg atagtggtgt ttttcgcgat cagcgtggtc atcacaccgc ccatggtttc
    29521 gatacccaga gacagcgggg taacgtccag cagcagtacg tcttttacgt caccagtcag
    29581 aacaccaccc tgaacagcag caccgatggc tacagcttcg tccgggttaa catctttacg
    29641 cggctcttta ccaaagaatt cagcaacttt cttctgaacc attggcatac gagtctgacc
    29701 accaacgagg ataacgtcgt cgatatcaga tacggacagg ccagcgtcct gcagtgcaac
    29761 tttcagcggc tcaatggaac ggtttaccag atcttcaacc aggctttcca gtttcgcacg
    29821 agtcactttg atgttcatgt gtttcggacc ggtcgcgtct gcagtgatgt acggcaggtt
    29881 aacgtcggtc tgctgagcgg aagacagttc gattttcgct ttttctgccg cttctttcag
    29941 gcgctgcatt gccagcggat cgttgcgcag gtcaatgccc tgatctttct tgaattcttc
    30001 aaccagatag ttgatcagac ggctgtcgaa gtcttcacca cccaggtggg tatcaccgtt
    30061 ggttgccaga acttcgaagg ttttttcgcc gtcaacttcg tcgatttcga taatggaaat
    30121 atcgaaagta ccaccaccca ggtcataaac cgcgatagta cggttgccag tacctttgtc
    30181 cagaccgtaa gccagcgcag ctgcggtcgg ttcgttgatg atacgtttta cttccagacc
    30241 agcgatacgg cctgcgtctt tggttgcctg acgctgagca tcgttaaagt atgccggtac
    30301 ggtaataaca gcttcagtta ccggttcacc caggtaatct tcagcggttt tcttcatttt
    30361 tttcagcact tcagcagaga tctgcggcgg tgccattttc tggcctttaa cttcgaccca
    30421 tgcgtcgccg ttatcagcag caataatttt gaacggcatg atggaaacat cacgctgtac
    30481 ttcttcgtcc tggaagcggc ggccaatcag gcgtttaatc gcaaacaggg tgttttgcgg
    30541 gttcgtcact gcctgacgtt tagccggctg accaaccaga gtttcaccat cctgggtata
    30601 ggcaatgata gaaggcgtgg tgcgatcgcc ttcggcgttc tccagtacac gaggagtggt
    30661 gccatccata atcgctacac aagagttggt agtacccagg tcgataccaa ttattttacc
    30721 catctaaacg tctccactat atattcggtc atcatgtggt tgtgagtctg taataggggc
    30781 gaaacgtctg gtttcaactg cccaatttca tttttttgca gactcactca ctgcggttga
    30841 ctactaaatg gggtcgtaac ccacgtcatc aagggggaga tgcaaaaatt ttttgtgctt
    30901 ttgcgcagaa atttcgcgat atggcaggac aagacgtgaa actgacagca attttattca
    30961 tataaagaat gaatcgcagc aaggcattca tcaaaaaatt gtaataaaaa gaaaatatta
    31021 cgtgcctgaa acttctcttt atcagcggta aactagtttc atccccttac ccctccccac
    31081 caagagaatc cttatgaaat ccgttattac gatttccgcc agcctggcga ttagcctgat
    31141 gctgtgctgc acggcgcagg caaacgacca taaaatcctc ggcgtcattg caatgccgcg
    31201 aaacgaaacc aacgatctgg cgctgaaact tcctgtttgt cgcattgtta aacgcataca
    31261 actctcagcc gaccatggcg atttgcagtt aagcggtgca tcgatttatt tcaaagccac
    31321 ccgaagcgcc agtcagaccc tgaatattcc ttcagaaata aaagaagggc aaaccactga
    31381 ctggatcaac attaacagcg ataacgacaa caaacgctgc gtctcaaaaa tcaccttttc
    31441 cggtcataca gtgaactcat cggatatggc cacgctgaaa attatcggcg acgactaacg
    31501 ccagaatata gaaaccacaa aaaatgaatg ttaattacct gaatgattca gatctggatt
    31561 ttctccagca ttgtagtgag gaacagttgg caaatttcgc ccggctgctc acccataatg
    31621 aaaaaggcaa aactcgcctc tccagcgtac tgatgcgcaa cgaactgttt aaatcgatgg
    31681 aaggacatcc cgagcgacac cgccgcaact ggcagctgat tgccggagaa ttacagcatt
    31741 ttggtggcga tagtatcgcc aacaaactgc gcggacacgg taaattgtat cgcgccattt
    31801 tgctcgatgt ttcaaagcga ttgaagctga aagccgacaa agagatgtct acgtttgaaa
    31861 ttgagcaaca gttactggaa caatttctgc gtaatacctg gaagaaaatg gacgaggaac
    31921 ataagcagga gtttctgcac gcggtcgatg ccagggtgaa tgagctggaa gagctgctgc
    31981 cgctgctgat gaaagacaaa ttattggcaa aaggtgtgtc gcatttgctt tccagccaat
    32041 tgacccgcat tttacgcacc cacgcagcaa tgagcgtgct tgggcatggt ttgctgcgcg
    32101 gcgcgggtct gggaggccct gtgggcgcag cattaaatgg ggttaaagcg gtcagcggca
    32161 gtgcctatcg cgtgacaatt ccagccgtac tgcaaatcgc ctgcctgcgc cggatggtta
    32221 gcgccactca ggtctgatac cggaaaccgg ggaaaatttt cattttcccc tcaaaagatc
    32281 gtagacactg ccccactggc tgattattat gccgcgccct gaaaacacta cagttattca
    32341 gggaaattat ttcaccattc attcgatgat gatttttgag gaattatggg caacactaag
    32401 ttggctaatc cggcaccgct gggcctgatg ggcttcggca tgaccaccat tctgcttaac
    32461 ctgcacaacg tgggttattt tgctctggac ggtattattc ttgccatggg cattttctac
    32521 ggcggcatcg cgcaaatttt tgccggtctg ctggagtaca aaaaaggcaa cactttcggt
    32581 ttaaccgcat tcacctctta cggttctttc tggctgacgc tggttgcaat tctgctgatg
    32641 ccgaaactgg ggctgaccga tgcgccaaat gcacagttcc ttggtgtcta cctgggtctg
    32701 tggggcatat ttacgctgtt tatgttcttc ggcacgctga aaggcgcacg cgttctgcaa
    32761 ttcgttttct ttagcctgac cgtgctgttt gccctgctgg cgatcggtaa cattgccggt
    32821 aacgccgcga tcatccactt tgccggctgg attggtctta tctgcggtgc cagcgcaatc
    32881 tatctggcga tgggtgaagt gctgaacgag cagtttggtc gcaccgttct gccgattggt
    32941 gaatcccact aattgttttg agatcccccc gctcgggggg atttttttat tcgctaactt
    33001 cgcgtcttgc actcttcggt ctgaatgctg caaccacttc cggtgccgtt tcaacgtatg
    33061 gcccttccag caactgaatg cagtacggta cgctggcaaa aataccgtgc accacaacgt
    33121 taccctcagc gtccttcaca ccttccagcg tctctttaat agacttcggt tgaccgggta
    33181 agttaaggat cagcgcctgt ttgcgaatca cccccacctg acgcgaaagg atcgcagttg
    33241 gtacaaaatg caggctgatc tggcgcatct gttcaccaaa gcctggcatc tcgcggtccg
    33301 ctactgccag cgtcgcatcg ggcgttacgt cacgacgcgc cgggccagtt ccgcccgtgg
    33361 taagcaccag atggcaactc atttcatcca ccagctcaca caacgtttgc tcgatgatcg
    33421 cctgctcatc gggaattaag cgggtttcca gttcaaacgg cgtggttagc gccgatgtca
    33481 gccattcttc cagcgcaggg atgcctttat cctgataaac gccgctggat gcgcgatcag
    33541 agatggaaac taagccaata cgtaaagtat tcatcaagat ttttccgttt aaacagtctc
    33601 gttaaacaga atgatacact gcgaagggag tgacagacag gtttcagaag aggtagcgtg
    33661 accgacttcc cggtcacgct aagaatgatt acagcagatc gccgatcatt ttttccagtt
    33721 tttcctggtc aacagcaaac ttacggatac cttccgccag tttatctact gccattggat
    33781 cctggttgtg ctgccacagg aactcggact cagtgatacg cgccggacgc gctttcactt
    33841 caccagtgta agacagttta cgttcgatag ccccttcgct ctccgccagc tctttcagca
    33901 gtgccggtgc gatggtcaga cggtcgcagc ctgccagttc cagaatttcg ccgatgttac
    33961 ggaagcttgc gcccataacc acggtttcat aaccgtgctc tttgtagtac tggtagattt
    34021 cagatacaga aaccacgcct ggatcttctg ccggagcgta ctctttctta tcggtattcg
    34081 ctttgtacca gtcaagaata cggccaacaa acggcgagat caggaacacg cccgcttccg
    34141 cacaagcacg agcctgagcg aaggagaaca gcagggtcag gttacagttg atgccttctt
    34201 tttccagctg ttccgcagca cggataccct gccaggtaga agccagtttg atcagaatac
    34261 gatcgttgct aatacctgca tcgttgtaga gtttgatcag gcgttttgct ttcgcaattg
    34321 acgcttcggt gtcataggaa agacgcgcat caacttcagt tgagatacgg cccggaacca
    34381 gtttcaggat ttccagacca atatttacgg ccagtttgtc ggtcgcgtcc acgatctgct
    34441 gcgcgcgatc gttgctctgc tgtttcgccc aggcgacagc atcatcaatc aacttacggt
    34501 attccggaat ctgcgctgcg ttaagaatga gagaagggtt ggttgtggca tcctgcggtt
    34561 gatacagctt cattgccgcg atgtccccag tgtcggccac tacggtggtg tactgacgaa
    34621 gggaggtcaa tttgtccgtc atgatagtat ttctctttaa acagcttgtt agggggatgt
    34681 aaccggtctg ccctgatgat atcacgacgc aacgtcagcg caaccgccga caagacggtt
    34741 atcgccaggc gagactgttt cggatttctg acactgcgtt gatatcgccc gccattttta
    34801 tacaaaacct catgtatgct acgcagaagt tatcaagtac ctcgtagcgt atatacttct
    34861 taaacaattg gtaacgttta cacaggaaag tcatcgcgac cggcaataag agggatatgc
    34921 atgccagatt ttttctcctt tattaacagc gtcctttggg gttcggtaat gatttacctg
    34981 ctcttcggcg caggttgttg gttcactttt cgcaccggat ttgtgcagtt tcgctacatc
    35041 cgccagtttg gcaaaagtct taaaaatagc attcatccac agccaggcgg tttaacctca
    35101 tttcagtcat tgtgtaccag tcttgcagcg cgcgtgggta gcggcaacct ggccggcgtt
    35161 gcgctggcaa ttaccgccgg tggacctgga gccgtcttct ggatgtgggt tgccgcattt
    35221 atcggcatgg cgacctcgtt tgccgaatgt tccctcgcac agctttataa agaacgtgat
    35281 gccaatgggc agtttcgtgg cggaccggca tggtatatgg cgcgcgggct ggggatgcgc
    35341 tggatgggcg ttctgttcgc cgtctttttg ctcatcgcct acggcataat tttcagcgga
    35401 gttcaggcga acgccgttgc gcgagccctg agtttttctt ttgattttcc cccgctggtg
    35461 acaggtatta ttctcgctgt ctttgctatg ctggcgatca ctcgcggtct tcatggcgtc
    35521 gcccggctca tgcaggggtt tgtcccgttg atggcgataa tctgggtact gaccagcctg
    35581 gtgatttgcg taatgaatat cgggcaactt ccccacgtca tttggtctat ttttgagagt
    35641 gcttttggct ggcaggaagc ggcaggcggc gcggcgggat ataccttaag ccaggcgatt
    35701 actaacggtt ttcagcgcag tatgttttcc aatgaggcgg gaatggggtc gacgccaaac
    35761 gcggcagcgg cagctgcgtc ctggcctccg catccggcag cgcaaggaat tgtccagatg
    35821 attggcattt ttatcgacac cctggtcatc tgtacggcaa gcgccatgct gatattactg
    35881 gcgggtaacg gcacaaccta catgccgctg gaaggtattc agcttatcca gaaggcgatg
    35941 cgggtgctaa tgggttcctg gggtgcggag tttgttaccc tcgtggttat tctgtttgcc
    36001 ttcagctcca tcgttgccaa ctacatttat gccgaaaaca atctcttctt tttacgcctg
    36061 aacaccccta aagcgatctg gtgtctgcgg atctgcacct tcgcaacggt catcggcggc
    36121 accttgctaa gtcttccgct gatgtggcaa ctggcagata tcattatggc ctgcatggct
    36181 attaccaatt tgaccgccat attactgctc tcgcctgtgg ttcataccat tgccagtgat
    36241 tatctacgcc agcgtaaact cggcgtgcgc ccggtgtttg atccgttgcg ttatccggag
    36301 atcggtcgcc agctttctcc ggacgcgtgg gatgatgttt cgcaggagta atcacaacta
    36361 tcgatcaact cattctcttt ttttgctaaa gtcggcataa atttcctgca aggactggat
    36421 atgctgattc ttatttcacc tgcgaaaacg cttgattacc aaagcccgtt gaccaccacg
    36481 cgctatacgc tgccggagct gttagacaac tcccagcagc tgatccatga agcgcggaaa
    36541 ctgacgcccc cgcagattag ctccctgatg cgcatcagcg ataaactggc gggtatcaac
    36601 gccgctcgct ttcatgactg gcagccagat ttcacaccgg aaaatgcccg ccaggcaatt
    36661 ctggcgttta aaggtgatgt ctacactggc ttgcaggccg aaaccttcag cgaagacgat
    36721 ttcgattttg cccaacagca tttgcgaatg ctttccggct tgtatggcgt actgcgcccg
    36781 ctcgatttaa tgcagcctta tcgtctggaa atggggatac gtcttgagaa tgcccgaggg
    36841 aaagatctgt atcaattctg gggagatatc atcaccaaca agctgaacga ggcgctcgca
    36901 gcacaaggcg ataatgtagt gataaatctg gcgtcagatg agtattttaa atcggtgaag
    36961 ccgaagaaat tgaatgccga gattatcaag ccagtgttcc tcgatgagaa gaacggcaaa
    37021 tttaagataa tcagcttcta cgctaagaaa gcacgcggtc tgatgagtcg tttcattatt
    37081 gaaaatcggc tgaccaaacc agagcaacta actggtttta atagcgaagg ttacttcttt
    37141 gatgaagctt cctccagcaa tggcgaactg gtgtttaaac gctacgagca gcgttaagtt
    37201 tgtagtcaat gccggatggc aatccggcat tgatatttag cgatgatgtt tgtcaggccc
    37261 cggacgatga tcgccacgat gatcattgtg cttgttatgg cgcggcgatg gcggcggtcc
    37321 atatgggtgc cagcgattgc ctcgccattc ataatgttgt ttccaccagc cgtggtcgcg
    37381 ccagtgaccg ccatcccagt aatagccacg attatcacga tcgcctatct gtaattttac
    37441 tgacgggact agcgtaattt ccgcagcctg cgctgccatg ggagcgaaca gaaccaggga
    37501 aagtgcgagt acgatagatt gcatcttttt cacaggttac tccttttatc attgcccgtt
    37561 atgggtcgat atccggagat tacgcgatga gaacggcagt tgttattctc cgcaatccta
    37621 atctctaagt taccgcattt attgagaatt tctccttttt ccctgtcgtt tttctccata
    37681 ttttcttcat aaaaaagccg ggctgcataa aagcaaaccc ggcctgattg agataatgaa
    37741 tagatgttac tgatgattca tcatcaattt acgcaacgca gcaaaatcgg cgggcaggtt
    37801 atgcgaaagc aagggtaaat cagcacgttc tgccagctct tttggcagat ccaacgtttc
    37861 accgagaatc gcttccacgc tctctttaaa ttttgccgga tgcgcggtgc cgaggaacaa
    37921 gccatattcg cctggattca actggtcacg cagcgcacga taagctacgg cagcgtgcgg
    37981 ctccgaggta tagcccagtt cttttaactc acgcattgtc tgttgcgtgg tttcatcatc
    38041 cacggctgca taccccagct ctttcagttg ccagattttg cggcggaaca actcttccac
    38101 acgcggccag ttgtttggct ggctaacatc catcgcattg gataacgtcg cctgagtcgc
    38161 tttgggtgac cactgaccgc cgtgcaggaa acgtggcacg gtatcattca cgttggtcgc
    38221 agcaataaaa cgcttcaccg gcaggccaag agatttcgcc agcaggcccg ctgtcaaatc
    38281 gccgaagtta ccgctcggca ccgagacaac cagctggttg cgcgcttcct gcggcaactg
    38341 cgccacggct tcaaagtagt agcaaatctg cgccagcaaa cggctgatgt taatggagtt
    38401 agcagagttt agccccagcg ccactttcag ctcttcatca tcaaacgcct gcttcaccag
    38461 cgcctgacag gcatcgaaat cgccgtcgat ggcaacagtt tcgatattgc cgcccaatgt
    38521 acagaacagt ttttcttgca gtggactgat tttgcctcgt ggatagagga taaccacttt
    38581 cacattcggt aaaccgtaga aagcatgagc cactgccgct ccagtatcac cggatgtcgc
    38641 ggtcagaatg gtcactggct tatcgcccgc aatatgggtc agcatttgtg ccataaagcg
    38701 accgccgaaa tctttaaatg ccagcgttgg cccgtggaac aattccagac aaccgacatc
    38761 gctttcaaca ttggcgaccg gagccgggaa ggcaaacgcc gcacgtacgc gctcttccag
    38821 gatttcctgc gggatttcat caccaataaa cgccgagagg atcttcgcac tgcgggtgac
    38881 aaaatccagc ttcagcatct catcaatttc agtcaggctg aattccggca ggtcgtgcgg
    38941 aaaaaacagc ccctgatttt tgcctaaccc ctgggttacg gcttgcgcaa agctgacctg
    39001 ctcattgtga tctttcagat tgtagagttt catttagttt tccagtactc gtgcgcccgc
    39061 cgtatccagc tggcaaatat gaacaaaacc ttcctgattt tgcaggtagt tcttacccaa
    39121 ccagtcggca acgcgctgag cggtatccgg cttgtcacac agagcgaaca aggtcgggcc
    39181 ggagccggag ataccgctcg caaccgcgcc gatttccgca accgcctgcc gcgcctgccg
    39241 gaagccaggc aataaccgtt cacggtaggg ttcagcgata acatctttca tcagcttcgc
    39301 ggcaagctca ggctgacggg aatagcaggc gtgaatgaat cctgccaaat gtcgcccgtg
    39361 cgcaatgcaa tcctggcggc gatactgcgc cggtaaaata gcccgggctt ctgccgtcga
    39421 gactttaatc cccggatacg ccagcaccca cagccactca tcaaaccctg gcacttgctg
    39481 actgatgatg tcgttttctt caatcatcaa ctgcatacca ccaagaaaac acggtgccac
    39541 gttgtcgtaa tgaatgctgc cggagatacg cccttccaac tcgcccatca aagccagcaa
    39601 acgagtgtca ttaagcggct tgccgcagtg ttcattcatc gccatcagcg ccgcgaccac
    39661 tgaacaggcg ctggagccta agcccgaacc gatcggcata ttcttttcca gagtcatcgc
    39721 cactggaatt tgcttgccaa gctcctggca aaaacgctcc cagcactgat aaacgatatt
    39781 ttcccgtggc tctgacggca gcttatcggc aaagcgtccg aggttgttga gactgaatgt
    39841 ctctgctgcc tcaaccgtga ctacatctcc gagcaatgca ccatcaacag gtgtcaccgc
    39901 cgccccgagc acatcaaacc cgacgctcat attggcactg gaagccgggg cataaacttt
    39961 aaccatgtca gactcctaac ttccatgaga gggtacgtag cagatcagca aagacaccgg
    40021 cagctgtaac gtcattgccc gcaccatatc cgcgcagtac caacggcagc ggctgataat
    40081 agtggctata gaaggccagg gcgttttcgc catttttcac tttgaacagc ggatcattac
    40141 catccacttc ggcaatcttc acgcggcaga cgccatcttc atcaatattg ccaacatagc
    40201 gcaaaacttt tccttcatca cgagccttcg ccacacgcgc ggcaaagaga tcgtcgagct
    40261 gtgacagatt cgccataaaa gcggcaacat caccctcggc gttaaactct gcgggcagca
    40321 caggttcaat ttcaatatcc gccaactcca gttcacgtcc cgtttcacga gcgagaatca
    40381 atagtttacg cgccacatcc ataccagaaa gatcatctcg cgggtccggt tcggtataac
    40441 ccatttcccg cgccagtgtg gtcgcctcgg agaaactcat gccttcgtct aacttgccga
    40501 agatataaga aagcgaacct gaaagaatgc cggagaactt catcaattca tcaccagcat
    40561 tgagcagatt ttgcaggttc tcaataaccg gtaatccagc cccaacgttg gtgtcataga
    40621 ggaatttacg ccgcgatttt tccgccgcat aacgcaactg atggtagtaa tccatcgacg
    40681 aggtgttggc ctttttgttc ggcgtaacaa cgtggaaacc ttcgcgcagg aagtcggcat
    40741 attgatctgc cacagcctgg ctggaagtac agtcaacaat gaccgggttc agcagatgat
    40801 attctttcac gaggcgaatt aagcgcccga gattaaacgg ctctttggct tgcgccagtt
    40861 cttcctgcca gttttccaga ttaaggccat gtacattggt gagcagtgcc ttcgagttag
    40921 caacaccgca gacacgtaag tcgatatgtt tattcttcaa ccagctttgc tgacgcttca
    40981 gttgctccag cagcgcaccg ccaacgccac cgacgccaat cacaaacact tcgataacct
    41041 gatcggtatt gaacagcatc tgatgagtaa cgcgcacgcc agtggtcgca tcatcgttat
    41101 tgaccacgac agagattgag cgttcagaag atccctgagc aatggcgaca atattgatgt
    41161 tggcgcgggc cagcgcggca aagaatttcg ccgagatccc acgtaaggtg cgcataccat
    41221 cacctaccac cgagataatg gccagccgtt ccgtcaccgc caacggctcc agtaagcctt
    41281 ctttcagttc caggtagaac tcttcctgca ttgcccgttc agctcgcaca cagtcgcttt
    41341 gcggaacgca gaaactgata ctgtattcgg aagatgattg cgtaatcagc accacggaaa
    41401 tacgggcgcg tgacatcgct gcaaagacgc gcgccgccat gccaaccatc cctttcatcc
    41461 ccgggccgga aacgctgaac attgccatgt tattcagatt ggaaatgccc ttgaccggta
    41521 attcgtcttc atcacggctg gcaccaatga gcgtacctgg tgcttgagga tttccggtat
    41581 ttttaatcag gcaagggatc tggaactggg cgatgggggt aatggtgcgg gggtgaagaa
    41641 ctttagcgcc gaagtaagaa agctccatcg cttcctgata ggacatcgac ttcaacaacc
    41701 tcgcatcggg cacctgacgc ggatcgcagg tataaacacc gtcaacatcc gtccagatct
    41761 cgcaacaatc ggcgcgtaaa caggccgcca gcaccgcagc ggagtagtcg gaaccgttgc
    41821 gtcccagaac caccagctcg cctttttcat taccggcagt gaaaccagcc atcagcacca
    41881 tgtggtcagc cggaatgcgg cttgccgcaa tacggcgggt ggattcagca atatcaacgg
    41941 tagattcgag gtaatgaccc actgccagca gtttttcgac cggatcgata acggtaacgt
    42001 tgtgaccacg cgcttctaac acgccggcca taatggcgat cgacattttc tcgccacggc
    42061 aaatcagcgc agcgttgatg ctatccgggc actgccccaa caaactgatg ccatgcagga
    42121 catgttttat ttgggcaaat tcctggtcga cgaaagtttt caattgtgcc agcggaaatc
    42181 ccggctgggc ggcggcgagt cccgtcagaa gttcggcaaa aatacgttcg gcatcgctga
    42241 tattgggtaa agcatcctgg ccgctaatag ttttttcaat catcgctacc agatggttgg
    42301 taattttggc gggggcagag aggacggtcg ccacctgccc ctgcctggca ttgctttcca
    42361 gaatatcggc aacccgcaga aaacgttctg catttgccac tgatgtaccg ccgaacttca
    42421 acactcgcat ggttgttacc tcgttacctt tggtcgaaaa aaaaagcccg cactgtcagg
    42481 tgcgggcttt tttctgtgtt tcctgtacgc gtcagcccgc accgttacct gtggtaatgg
    42541 tgatggtggt ggtaatggtg gtgctaatgc gtttcatgga tgttgtgtac tctgtaattt
    42601 ttatctgtct gtgcgctatg cctatattgg ttaaagtatt tagtgaccta agtcaataaa
    42661 attttaattt gatcacggca ggtaaccagt tcagaagctg ctatcagaca ctcttttttt
    42721 aatccacaca gagacatatt gcccgttgca gtcagaatga aaagctgaaa atcacttact
    42781 aaggcgtttt ttatttggtg atattttttt caatatcatg cagcaaacgg tgcaacattg
    42841 ccgtgtctcg ttgctctaaa agccccaggc gttgttgtaa ccagtcgacc agttttatgt
    42901 catctgccac tgccagagtc gtcagcaatg tcatggctcg ttcgcgtaaa gcttgcagtt
    42961 gatgttggtc tgccgttgtg tcacttttcg ccggttgttg tattaatgtt gctaattgat
    43021 agcaatagac catcaccgcc tgccccagat tgagcgaagg ataatccgcc accatcggca
    43081 caccagtaag aacgtcagcc aacgctaact cttcgttagt cagcccggaa tcttcgcgac
    43141 caaacaccag agcggcatgg ctcatccatg aagatttttc ctctaacagc ggcaccagtt
    43201 ctactggcgt agcgtagtaa tgatatttcg cccgactgcg cgcagtggtg gcgacagtga
    43261 aatcgacatc gtgtaacgat tcagctagtg tcttgaaaac tttaatatta tcaataatat
    43321 caccagatcc atgtgcgacc caacgggcgg ctggctccag gtacgcctga ctatcgacaa
    43381 tccgcagttc gctaaaaccc atcgttttca ttgcccgcgc cgctgcccca atattttctg
    43441 ctctggcggg tgcaaccaga ataatcgtta tacgcatatt gccactcttc ttgaccaaat
    43501 aaccgcgaac agggtgatca ccgtcaactt attacgcggt gagaatttac aaattcttaa
    43561 cgtaagtcgc agaaaaagcc ctttacttag cttaaaaaag gctaaactat ttcctgactg
    43621 tactaacgat tgaattgtta aaaaatgcta catatccttc tgtttactta ggataatttt
    43681 ataaaaaata aatctcgata attggattca ccacgtttat tagttgtatg atgcaactag
    43741 ttggattatt aaaataatgt gacgaaagct agcatttaga tacgatcatt tcatcaaact
    43801 gttaacgtgc tacaattgaa cttgatatat gtcaacgaag cgtagtttta ttgggtgtcc
    43861 tgcccctctt agcctgttat attgctgtta aaatggttag gatgacagcc gtttttgaca
    43921 ctgtcgggtc ctgagggaaa gtacccacga ccaagctaat gatgttgttg acgttgatgg
    43981 aaagtgcatc aagaacgcaa ttacgtactt tagtcatgtt acgccgatca tgttaatttg
    44041 cagcatgcat caggcaggtc agggactttt gtacttcctg tttcgattta gttggcaatt
    44101 taggtagcaa acatgcagac cccgcacatt cttatcgttg aagacgagtt ggtaacacgc
    44161 aacacgttga aaagtatttt cgaagcggaa ggctatgatg ttttcgaagc gacagatggc
    44221 gcggaaatgc atcagatcct ctctgaatat gacatcaacc tggtgatcat ggatatcaat
    44281 ctgccgggta agaacggtct tctgttagcg cgtgaactgc gcgagcaggc gaatgttgcg
    44341 ttgatgttcc tgactggccg tgacaacgaa gtcgataaaa ttctcggcct cgaaatcggt
    44401 gcagatgact acatcaccaa accgttcaac ccgcgtgaac tgactattcg tgcacgcaac
    44461 ctgctgtccc gtaccatgaa tctgggtact gtcagcgaag aacgtcgtag cgttgaaagc
    44521 tacaagttca atggttggga actggacatc aacagccgtt cgttgatcgg ccctgatggc
    44581 gagcagtaca agctgccgcg cagcgagttc cgcgccatgc ttcacttctg tgaaaaccca
    44641 ggtaaaattc agtcccgtgc tgaactgctg aagaaaatga ccggccgtga gctgaaaccg
    44701 cacgaccgta ctgtagacgt gacgatccgc cgtattcgta aacatttcga atctacgccg
    44761 gatacgccgg aaatcatcgc caccattcac ggtgaaggtt atcgcttctg cggtgatctg
    44821 gaagattaat cggctttacc accgtcaaaa aaaacggcgc tttttagcgc cgtttttatt
    44881 tttcaacatt atttccagat acgtaactca tcgtccatgg taacttcttt actggctttc
    44941 attttcggca gtgaaaacgc ataccagtcg atattacggg tcacaaacat catgccggcc
    45001 agcgccacca ccagcacact ggttcccaac aacagcgcgc tatcggcaga gttgagcagt
    45061 ccccacatca caccatccag caacaacagc acgagggtaa acaacatgct attacgccag
    45121 cctttcaata ccgcctgcaa ataaataccg ttcattaacg ccccaatcag actggcgatt
    45181 atccatgcca cagtaaaacc ggtatgttca gaaagcgcca gcaagagcaa ataaaacatc
    45241 accaatgaaa gccccaccag caaatattgc attgggtgta aacgttgcgc ggtgagcgtt
    45301 tcaaaaacaa agaatgccat aaaagtcagc gcaatcagca gaatggcgta cttagtcgcc
    45361 cggtccgtta attggtattg atcggctggc gtcgtcactg cgacgctaaa cgcggggaag
    45421 ttttcccagc cggtatcatt gcctgaagca aaacgctcac cgagattatt agcaaaccag
    45481 ctactttgcc attgcgcttg aaaacctgac tcgctaactt cccgtttggc tggtagaaaa
    45541 tcacctaaaa aactgggatg cggccagttg ctggttaagg tcatttcgct attacgcccg
    45601 ccaggcacca cagaaagatc gccggtaccg cttaaattca gcgccacatt cagcttcagg
    45661 ttctgcttgc gcaagtcccc ttcgggtaaa gggatatgca cgccctgccc gccttgctct
    45721 aacccggtgc cgggttcaat ggtcagcgcc gtaccgttaa cttcaggcgc tttcaccaca
    45781 ccaataccac gcgcatcccc gacgctaatc acaataaatg gcttgcctaa ggtgatattt
    45841 ggcgcgtcga gttcgctaag acgcgaaaca tcgaaatcgg cttttagcgt taaatcactg
    45901 tgccagacct gaccggtata gatgcctatc ttgcgttctt ccacattctg attgccatca
    45961 accatcaatg actcaggtaa ccaaaaatga ataaaacttc gtttccgctc cacggtttta
    46021 tcgtcttcct gcaccgtata aagctcggtc acaggaatag cgatgagcgg cccaacgagt
    46081 ttttgcggcc cgctggtact ttggcgaatc acatcttcca catcgctacg gtaatcggca
    46141 cgttcgacaa tcacctgccg aatcagcatt atcggaatca acaacagcaa tactgcacca
    46201 aacaaggtgg tcattttcca gaacaggggg gatttcaaca tagtcttctc ctttgcaatg
    46261 acagcaggat acgaaggcta tgtgggaaga atttgaagct atgtgaagtg acggtgaagt
    46321 cgaagcgagg ccagcacgcc accttcctgc acgttgcgca gcgtgacttc gccgttaaac
    46381 aaacgggcga cctcactgac aaacgccaac cccagaccgc tgcttttttg cccatttgca
    46441 cgcggcaaag agtaaaagcg ttcaaaaata cgtgacagcg cgtagtcagg aatcccacta
    46501 ccggtatcca gcaccttaag ggtgacgtat tcctgatcca cttcggcgct tagcgttatg
    46561 cgaccgctct cgggagtaaa atcgatggcg ttatccagta aattccccag cgcctgctcc
    46621 agtaacgccg gttcagcagc aacgttaatc tcagtaggca taacatgcaa agtgatgttt
    46681 ttttctgcca actgcacggt gcgcgcttcg ctgacgcggc gaaataatgc cgccacatca
    46741 acagcagtca gaacgacttc ctgacgattc tccagtcttg cctggcgtag taacgtttcc
    46801 accagtgcct gcattcgcgc attttgcgtc agaatgttgt cggtaaaacg agccaccact
    46861 tccggcggcg gaccttcgcg taaaatttcc gccgcgccac gaatcgccgc cagtgggctt
    46921 tttagctcat gagttaacgc ataaacatac tgctcaatat agtttttccc ttccagcttc
    46981 acgcgcatac tttccagcgc ctgcgcgagt ttacgcagct cgctactacc gagatcgggg
    47041 agaggaacgg gcttattgtc agtgacggaa tcagcatagc gagtgagccg ggcaatagag
    47101 cggttgatcc accaaaccat gcctgcgcca atcaccagtg caatccccaa caaaatggcg
    47161 ctggcccata aaattcgccg ctcgctacgc ttaatgaccg gggccatcgc cgcgttcggt
    47221 ttgcctacgc tcaaaacgcc aataagccgc gagccgtcca taatcggcgc ggcaacatac
    47281 atcacagaac tttcgggatc ggcaggattt tgcaacgtgc tgcgcgcacc atactgacca
    47341 cgcaacgtta gccagacgtc attccagcgc gaataatcct gtccaacggc tttatttgcc
    47401 gaatcaaaca atactttgcc ctgcgcatcg gtcatataga catgatattc gttgcgcact
    47461 ttgttaatgc caccgatatt ggcgcgaaac gggcgatgtt gtagctgatt aaacgcctgc
    47521 gccagttgcc catgcgttgg gtccccagag agcaaatcgg gacgcgccag ctccgccagc
    47581 aacgttgcgg tgtcgattaa cgtcccctcg gttgctcttc gcacgcccgg tttaacttct
    47641 ttgacaaaaa tagccagtac gaaccaggcc gccaccgcca ccagtaaaaa atagcccagc
    47701 aacaaccgca tgccgatacg cattacaggc ccctcaggct atatcccatg ccgcgatgag
    47761 tattaatcgg tgaaagatcg gggttgatgg cgcgcagctt ggcacgcagc gttttaatgt
    47821 gggtatcgac ggtgcgatcg taggtgtcct gcgcatcttc ccacacgcta tccattagtt
    47881 gctggcggga ccagacgcgg cccggcgact tgagtaacgt cttcagcaat aaaaactcat
    47941 accgcgtcag cgttaatggc gtgtcaaacc agctgatctg cgccgcaggt tcattcaatt
    48001 caaaatgacc aatacggata acgggagacg gcgtcgagaa cttcttcacc cgacgcagta
    48061 aggtgcgcac tctggcgcac acttcgcgag gtgaaaacgg tttagccacg tagtcgtcag
    48121 cgccaatttc cagcccaagc aggcgatcga cctcttcact tcgggccgtc aggaacagta
    48181 caggtaacgc cggatggagc gccagtaact ggcggcacaa ttcaaagccg ctgatatcag
    48241 gcaaaccaac atcgagaatc atgacatcgg gaacctgctg gcgagcttta tccagcactg
    48301 gcaagcctcg ctcaaagacc tcgacgccaa aaccttcctg ttgcaacatg tagaccagcg
    48361 tatcggctat cccttgctcg tcttctacta accagaccgt ttcccgttgc ataaatcgcc
    48421 tctgttattg ccgccacggc atgacaggaa ccgcgctaat cgcgtttttc ggcgaacctt
    48481 ctacaacttt gtcggagtaa gccagataag cgagcgcgtt gcgtttagcg tcataaaagc
    48541 gcacgacctg taacgactta aagaccaggg acgtgcgttt tttgaatact acctcgccct
    48601 gagctttgcc gtttttaata cgatccgaca gttcaatcgg cccgacttgt tgacaagaaa
    48661 tggccgcatc ggaggtatct tctgccaggc ccaatccccc tttaatacca ccggttttcg
    48721 cccggctcac ataacaggtg acatttttca catcgggatc gtcaaaggct tcaacaacaa
    48781 ttttgtgatc cgggccgatc attttaaata cggtgtcgac cgaaccaatc tcttctgcat
    48841 gagccaatgg ccccagcatt atcaggctta aagaaaggat taaatgcttg tatttcatat
    48901 tgttaccatt tttatctatt acacgagcaa ttagttcgtc acggtaaata acatattgat
    48961 taagaacaaa atctcaatac ttttatttcc gtcaagccct aaaacatact cgactaagaa
    49021 aaaaacactg aatgctaaaa cagcaaaaaa tgctattatc caattacctg atgtcaggtg
    49081 ctcgttgttg aaaggatgag gatattttat ggatcaggcc ggcattattc gcgacctttt
    49141 aatctggctg gaaggtcatc tggatcagcc cctgtcgctc gacaatgtag cggcgaaagc
    49201 aggttattcc aagtggcact tacagagaat gtttaaagat gtcactggcc atgctattgg
    49261 cgcgtatatt cgtgctcgtc gtttgtcgaa atcggcggtc gcactacgcc tgactgcgcg
    49321 tccgattctg gacatcgcgc tgcaataccg cttcgactct caacagacat ttacccgcgc
    49381 attcaagaag cagtttgccc agactcctgc actttaccgc cgttctcctg aatggagcgc
    49441 ctttggtatt cgcccgccgc tgcgtctggg tgaattcact atgccagagc acaaatttgt
    49501 caccctggaa gatacgccgc tgattggtgt tacccagagc tactcctgtt cgctggagca
    49561 aatctctgat ttccgccatg aaatgcgcta ccagttctgg cacgattttc tcggcaacgc
    49621 gccgaccatt ccgccggtgc tctacggcct gaatgaaacg cgtccgagtc aggataaaga
    49681 cgatgaacaa gaggtattct ataccaccgc gttagcccag gatcaggcag atggctatgt
    49741 actgacgggg catccggtga tgctgcaggg cggcgaatat gtgatgttta cctatgaagg
    49801 tctgggaacc ggcgtgcagg agtttatcct gacggtatat ggaacatgca tgccaatgct
    49861 caacctgacg cgccgtaaag gtcaggatat tgagcgatac tacccggcag aagatgccaa
    49921 agcgggagat cgcccaatta atctgcgctg tgaactgctg attccgatcc gtcgttaacg
    49981 ctgcagctca tctaatgcag gggcgtccag atgcgagatg tcccctgcgg tttcaaccac
    50041 ccagccagac gccagccaca ggctttcctg ataatccacg cgcgaaatag aacagttacg
    50101 cagacgtaag cggcgctctg cccatgctgg taatccgaga atcgtactca ccaggcatcc
    50161 cagtgcaata ccatggctca ccagtagcgg tcggcttccc tgcggtaagt cccggcaaga
    50221 ttccagtgcc gcattaacgc gatcgctgag ctcctgcatt gactcgcctt caggaatacg
    50281 cccgtcaacg gtgccattga ccagttgccg acgccagttc tcttcttctt cggtgagtga
    50341 atcgatattt cttgtttcca gtacacccat atttaattca cgcaggcgag aatcaaatat
    50401 gatgtcacag ccgcaggcct gggcgatgat ttccgccgtg cgccgggtgc gtcctaaatc
    50461 gctactgatg atatgcgtaa tgccaagctc tttggcacgg gttgccacct gcatcgcctg
    50521 ttgctcacct ttggcggtca gcgggctgtc agactggccc tgaatacgtc gctcggcgtt
    50581 ccactgcgtt tcaccgtggc ggactaggta tacctgtaac atgctttttt tccgtatact
    50641 gctgtaacgt taattttctg agtaatgctg attatgcacc aagttgtctg tgcgaccacc
    50701 aatcccgcta aaattcaggc cattctgcag gcatttcacg agatcttcgg cgaaggatcc
    50761 tgccatattg catccgttgc cgtcgagagc ggtgtaccgg aacagccctt tggcagtgag
    50821 gaaacgcgcg ctggcgcacg aaatagggta gccaatgccc gccgtttact tcctgaggct
    50881 gatttttggg tggcgattga agctggcatc gatggtgaca gcactttcag ttgggtggtg
    50941 attgaaaacg ccagccagcg cggcgaggcg cgttcggcta ctttgccgtt gcctgcggtg
    51001 attctggaaa aagtgcgtga aggtgaggcg cttggtcccg tgatgtcgcg ttataccggt
    51061 attgatgaga ttggtcgtaa ggaaggggcg atcggcgtgt ttaccgccgg gaaactcact
    51121 cgcaccagcg tctatcacca ggcggtgatc ctggcgctga gtccgtttca taatgccgtg
    51181 tatcagccat tgcaggcctg attaggcgtt cacgccgcat ccggcattcg gtgcacgatg
    51241 cctgatgcga cgctgacgca tcttatcagg cctacaaaat caatcgcttt tcagcaacac
    51301 gtcttccagc cactggcgca gctcgacggg cgcggctttc agactattag atccacgcgt
    51361 aatcgtcgcg atgcccgcgc cgagttcatt ttttaactca cgctggctca tttcgccgcg
    51421 caacagctct tcgacaatac gcacgcgagt ccccaacgct tcgcgctcat ctggcgtcag
    51481 catcaggttt aacaacggta aatggagatc gttttggtag gcattcttaa gcaggtcgac
    51541 aaaacgtaac cactcctggt gacgctgttc tgccatcgct gctgaatagg gtgattgttg
    51601 ggccatagta tgtcgccatt gttagcgggg gaagcaaaat gcctcccccg gttgtactcg
    51661 ctaaagagta cgatagcata tcataaacgt gtggatcagt aacgacgtcc ccattccgtg
    51721 gcgctcatca acgtcggttt atcccccatg aaatagcggt agtaagcgtc ataagccagc
    51781 acgtttttca cataaccgcg cgtctcggag aatggaatac tctcgacaaa tgccactgcg
    51841 tcgatacgcc ctgcgctgtt gccaagccag gtccgcaccc gccctggtcc ggcgttataa
    51901 gctgctgagg agaaaatacg gttattgcca aactgctgat aaacatattg caggtaactg
    51961 gtgccaatgt tgatgttcgt ttccggatcc agcaattgcc cagggctgct ataaccggga
    52021 atagagaaca tcttcaccgt atgggtcgcg gtaccaggca taatctgcat caggccgctg
    52081 gcccctaccg gtgatttcac tttcggattc caggcactct cctgacgagc aatcgccatc
    52141 gcatagcttt gcgggatctc cttaccactg gtgtagcgtt tgaaaagatc gttgtaagcc
    52201 agcgggaatc gctcttccag atgatcccac agcttcccgg cgatcgttgc ctgaacgcta
    52261 agatcccacc attggttatt gaaagcatac cgagccagtt gagcctgctc tgtttttgac
    52321 ttgctcttca ccagattggc ccactcgcta cgcgcggtgt tatcgagatt ccagtacatc
    52381 aactcgcgca cgcgcgccat ctccggcccc tgagtcaggg cgctgtcaac attctgcggc
    52441 gctttatcaa tcttcagctc atactcttcg ccgatgcgtt gtgcagcaac catcgggtag
    52501 aaaccacgct gttgcatgag ttgatgcaaa atctcttttg cttcagcttc acgtccgcgt
    52561 tccagcagta aatccgcctg ccagtaacgc cattcatctt tctctttcgc ttccataggc
    52621 agacgcgcca gccaggtatt caggccgcga cgatcgccgg tgccaagcgc cattcgcaca
    52681 cggcgttcaa taagcgaagt agattgcgag cgcataatcg cgtcatcgcg ccatttcgcc
    52741 tgctcgtcgg tgacatcgtt gcccatcaaa cgccaggcga caatatcgcg cagctcctga
    52801 atctgatctt cattaagctg ctgtgcctga gcaagcgacg ggatcatcag ccgtgcattt
    52861 tcagcatcct gccgcgccac actggcaaac gccaccgccg ccatttgacg ggtaaaatcg
    52921 gtcgcgccgg ttgtacgcgc gaaggtcagt accgtattag ggttgttcgc cagtgaaatg
    52981 attgccgaag cgatagtctg gtaatcggca ggcatctgcc ctgccagcac tgttaccagg
    53041 ccggtgttac ccgctttcat cgccagacgg atacgctcta aatacgccag cggatcttgt
    53101 ttacctgacg cacgccagac gctaaataac ttgtcacagg cgttaggctg gctcttgccg
    53161 gttagccaca gctctttcgc cccttgccag gcttcttcac tctgcccggt gttccatttc
    53221 gcatagtagt aattacattg cgcttcggta gttccgggct tttccgggct aaaggctaac
    53281 aagccacgcc agtcttcacg ccgcgccagt tcattgacga aacgagattg cagcgtgcga
    53341 gcgggaggaa gcgtggggtt agcgcgaaca aagttagtga ccgtcaccgc cggttgattc
    53401 atcaggtcat cagtgatctg gcggtattcc aggtagggat aaagtgggta atctttcagt
    53461 ccaggcatca tttgttcgac cacatccatt tgtcgattat cccaggcctg cttaatttgc
    53521 gcgtaacggc tacgctgctc atccagtgag tcggctcgcg ccacgctgct gaccgtcagc
    53581 agacagacac cggcagccaa cagccgccag gtaacgtgtt tggctttttc cacaagcgca
    53641 tcctctaagt gtaaatacat caatgcagcg tcatgccgcg taatagattt atgctaacca
    53701 gtcattgccg tttacgccac gttacggaca cttttttact tttacggggt gatcgactgg
    53761 ctgggattag acagggaaac aggctacact tcgcctttga aaactcatca tcacgataaa
    53821 catagaggcg aagtccaacg tggctcaatt cgtttatacc atgcatcgtg tcggcaaagt
    53881 tgttccgccg aaacgtcata ttttgaaaaa catctctctg agtttcttcc ctggggcaaa
    53941 aattggtgtc ctgggtctga acggcgcggg taagtccacc ctgctgcgca ttatggcggg
    54001 cattgataaa gacatcgaag gtgaagcgcg tccgcagcca gacatcaaga ttggttatct
    54061 gccgcaggaa ccgcagctga acccggaaca caccgttcgt gagtccattg aagaagcggt
    54121 ttctgaagtg gttaacgccc tgaaacgcct ggatgaagtg tatgcgctgt atgccgatcc
    54181 ggatgccgat tttgacaagc tggccgctga acaaggccgt ctggaagaga tcattcaggc
    54241 tcacgacggt cacaacctga acgttcagct ggagcgtgcg gcggatgcgc tgcgtctgcc
    54301 ggactgggat gcgaaaatcg ctaacctttc cggtggtgag cgtcgtcgcg tggcgttgtg
    54361 ccgcctgctg ctggaaaaac cagacatgct gctgctcgac gaaccgacca accacctgga
    54421 tgcggaatcc gtagcgtggc tggagcgctt cctgcacgac ttcgaaggca ccgtggtggc
    54481 gattacccac gaccgttact tcctcgataa cgttgcgggc tggatcctcg aacttgaccg
    54541 cggtgaaggt attccgtggg aaggtaacta ctcctcctgg ctggagcaga aagatcagcg
    54601 tctggcgcag gaagcttcac aagaagcggc gcgtcgtaag tcgatcgaga aagagctgga
    54661 gtgggtacgt cagggaacta aaggccgtca gtcaaaaggt aaagcacgtc tggcgcgctt
    54721 tgaagaactc aacagcaccg aatatcagaa acgtaacgaa accaacgaac tgtttattcc
    54781 acctggaccg cgtctgggcg ataaagtgct ggaagtcagc aacctgcgta aatcctatgg
    54841 tgatcgtctg ctgattgact ccctgagctt ctcgatcccg aaaggagcga tcgtcgggat
    54901 catcggtccg aacggtgcgg gtaaatcgac gctgttccgt atgatctctg gtcaggaaca
    54961 gccggacagc ggcaccatca ctttgggtga aacagtgaaa ctggcgtcgg ttgatcagtt
    55021 ccgtgactca atggataaca gcaaaaccgt ttgggaagaa gtttccggcg ggctggatat
    55081 catgaagatc ggcaacaccg agatgccgag ccgcgcctac gttggccgct ttaactttaa
    55141 aggggttgat cagggtaaac gcgttggcga actctccggc ggtgagcgcg gtcgtctgca
    55201 tctggcgaag ctgctgcagg ttggcggcaa catgctgctg ctcgacgaac caaccaacga
    55261 cctggatatc gaaaccctgc gcgcgctgga aaacgccctg ctggagttcc cgggctgcgc
    55321 gatggttatc tcgcacgacc gttggttcct cgaccgtatc gccacgcaca ttctggatta
    55381 ccaggatgaa ggtaaagttg agttcttcga aggtaacttt accgagtacg aagagtacaa
    55441 gaaacgcacg ctgggcgcag acgcgctgga gccgaagcgt atcaagtaca agcgtattgc
    55501 gaagtaatgc gtaaaatgcc ggatgcggcg taaacgcctt atccggccta caaaccaagc
    55561 aatttcaata cgttgtgaat ctccaggcct gataagacgc ggtaagcgtc gcatcaggca
    55621 ttggttctta cctctgctcc cccatcatct cccgcaccag ctccacgcag cgcagaaaac
    55681 ggctgtcgta atcgtcctct tcaacccgca cgaattcgat attgttctct tccagcatct
    55741 ccaccagcaa gttctggaac tctttgcgat ccaccgaact gccgaggctg cgtaaaccat
    55801 ccgccaccca cggcgtgttg ttctccagca ggatcaccag atcgaaacgg tattcatcaa
    55861 tcaacgcctg cacaaacgga tgctcacgcc cttcgtactt tttgcagaac gcctgggtag
    55921 tgacaaaatc ggtgtcgata aacgccactt tattggcata tttcactgca aaatcaatat
    55981 attgcgcatg tcccagcgcg attttatcgt agtcggaata ctgcaacgcg atctcatcgc
    56041 caccgaggtg cgaaaagaca taatcacgac catattccca cgcactggta gtgttgaaga
    56101 tattggcaag tttgtttacc agggtggatt taccgctcga ttcaccaccg aggatcgcca
    56161 cggtacgcac aaagaatggc ttcacttccg taggaatata ttcccagtag cggaacgggt
    56221 tttcgcggat ctgcgcaccg ctgatactca taaaggtacg cttcggatcg accagcaccg
    56281 tctcgatccc cagatgttcc atatactgtg gcgcatcggc ttcttccgag gtgtagatca
    56341 ggtccggctg aatccctttt tcagccataa actttttgat gccgttgctc catacatccc
    56401 agccgtgtgg atatggctcc atgccctctt cattgaaagc atgaatacgg atatttttct
    56461 gatatttaaa ggtttgcaat agccagcgca gacgatccgg caccgtgggc tgctgcgaca
    56521 tggcgctgtc ttcgaacaat gcgcggtcgc gggtatcgtc aaaacccata atgatatgca
    56581 gctcgtcaac ctggctacag gcgcgctgga taaggtagat atgtccggta tgcagcgggt
    56641 aaaacttacc gaatacgaca ccgatcgttt tcttctgccg gggaaattca agtcccaaat
    56701 aacggtgcaa tgcctccagc ttttgtgcgc tggggctttt aattttggca ttcagtaact
    56761 ggcttaaata ccctttggtc ataccgctgg catcagctac ctgctgtagc gtgcagccct
    56821 gttgcttgat ggcagttttc aggtaatcaa atgacgacat atctccctcc gtatctctca
    56881 ttataagtcg tcgaacacgc taagcgcgtc ggagagtttt ttaacgccaa aaatctgcat
    56941 cccttccggc gtttttttcg gcacgttagc cgccggaaca atcgcccggc gaaaaccgtg
    57001 tttcgccgct tctgagattc gttcctggcc gctgggcacc gggcggatct cccctgccag
    57061 cccgacttca ccaaacacca ccagatcctg cggtagcggt ctgtcacgca ggctggaaac
    57121 catcgccagc agtaacgcta aatcggcact ggtttccgtc accttcacgc caccgaccac
    57181 gttaacaaac acatcctgat cggccatttg tagaccaccg tgacggtgaa gcaccgccag
    57241 caggattgcc agacggtttt gctccagccc gactgccacg cggcgtggat tcgccatcat
    57301 cgagtgatcg acgagcgcct gaatctccac cagcagcgga cgcgttcctt cccacactac
    57361 catcactgag ctaccggagg tcacttcatc gccgcgactt aagaaaattg ccgaagggtt
    57421 gctgacttca cgcagcccct gctcggtcat tgcaaagaca cccagctcat tcaccgcgcc
    57481 gaagcggttt ttatggctgc gtaaggtgcg aaaacgggag tcggcatcgc catccaaaag
    57541 caccgaacag tcgatacagt gttccagcac tttagggcca gccagcgagc catctttggt
    57601 tacgtgccca accatgacaa tcgccacacc gcgcgttttg gcgaagcgcg tcagataagc
    57661 cgccgtttca cgcacctgtg ccacgctgcc aggcgatgat tgtacatccg ccatatgcat
    57721 cacctggatg gagtcaatta ccatcagctt cggttgctct tcttcggcaa tcaggcagat
    57781 ctgctcgatg ctggtttccg acagcatatt aagattgtca gtcggcaggc caaggcgatg
    57841 agcgcgcatt gccacctgtt gcagcgactc ttcgccggtg acatacagcg ttttcatctg
    57901 ctgcgccagt ttgcacagcg tttgcagcaa cagcgtggat ttccccgcac cagggttacc
    57961 gccaatcaga atggcgcttc ccggcaccac gccgccgcct aatacgcggt cgaactcttt
    58021 aaatccggtg gaaaaacgcg gcagctcttc aaggctgatg tcggaaagtt tctggacttt
    58081 tgccactccg gcgctaccgg catagccact gagacgctcg ttacgcgcca ccgttggcga
    58141 cgctgcaaga cgcacctcgg tgatggtgtt ccaggcatga caggcactgc actgcccctg
    58201 ccagcgcgga taatcggccc cgcattcatt acaaacaaag gcgcgttttg gagcttttgc
    58261 cacgatgtac ctcgttaatg ctgtgccgcc cgcaggatga cgggcggaca attacttctg
    58321 attcaggctg ccagagagga tgcagaatac ccccatcagg tcagcgtgac ggatggtgac
    58381 ttccgtcttt tcattcactt ttggcttggc atggtaggca atccccagcc ctgccgcttt
    58441 gatcatcggc aggtcattgg ctccatcgcc aatcgccacg gtctgcgcca gcgggatttc
    58501 atactcctgc gcgaggcggg tcagggtttt cgctttatat tgcgcgtcaa cgatgtcgcc
    58561 gatcacattg ccggtaaatt taccgtccat gatctccagt tcattggcta ccacggctgt
    58621 caggcgcagc ttgtcgcgca ggtattcagc aaagaaagta aagccgccgg aggcaatcgc
    58681 cactttccag cccagcgttt ccagcttgag taccagctgc gttaagcctg acatcagcgg
    58741 cagattttca cgcacctgtt gcagaatatt ggcgtcagcg cctttcagcg tcgccacgcg
    58801 gctgcgcagg ctggcggtaa aatcgagttc gccgcgcatc gcccgttcgg ttacctccgc
    58861 caccctctcg cccgttccgg ccagtttggc aatttcatca atacattcaa tctggatggc
    58921 ggtggaatcc atgtccatca ccagcaaacc cggcgtgcgc aggtgtggga ttttccccag
    58981 cggtgcgaca tccagttgcg cttcatgggc caggcgcgta gcccgcgcag tgagtgaacc
    59041 tgccagacga atcacctgat aatcttccac gcaccaggcg gcaacaatca ccatagccgc
    59101 gcccagtttg ctctggtatt gggtcagacg ttgtttatcc agcccacgac catacagcag
    59161 ccagccgcta cgacctgcgt ggtaatccag tggcatcact tcatcaccac ttaatgaaag
    59221 aggcagacca ggccataaag agacatcttc aggcaagtcg caccaggtaa tgttaggcat
    59281 taaggctcct gtaaaatcgt tcgaagcagg gaaaataacg catgaggcta ccttgtatcc
    59341 attgcttctg gcaacattaa gtctcaaatt ttcaaagggt ggaagatggc tcgcacaaaa
    59401 ctgaaattcc ggctgcatcg ggcagtgatt gtcctgttct gtcttgcctt gttagtggcg
    59461 ctgatgcagg gggcgtcatg gtttagtcaa aaccaccagc gacagcgtaa tccgcaactg
    59521 gaagaactgg cccgcaccct ggcgcggcag gtgacgctaa acgttgcacc gctgatgcgt
    59581 accgactcac cggatgaaaa acgcattcag gcgatcctcg atcagttaac ggatgaaagc
    59641 cgcattctcg acgcaggcgt atatgatgaa caaggcgatc ttatcgcccg ttctggcgaa
    59701 agcgtcgacg tgcgcgaccg gctggcgctc gacggcaaaa aagcgggcgg ctattttaat
    59761 cagcagattg tcgaacccat tgcgggtaaa aacggaccgc tcggctatct gcgcctgacg
    59821 ctcgacaccc atacgctcgc caccgaagcc caacaggtgg ataacaccac taacatttta
    59881 cgcctgatgt tgctgctctc gctggcaatc ggcgtagtgc tgacccgcac gctgctacag
    59941 ggtaaacgca cccgctggca gcaatcgccc ttcctgttaa ccgccagcaa accggtgccg
    60001 gaagaggaag aaagcgagaa aaaagagtga cccattacta caagaaagga aatcgttatg
    60061 tccacattac gcctgctcat ctctgactct tacgacccgt ggtttaacct ggcggtagag
    60121 gagtgtattt ttcgccagat gcccgccacg cagcgcgttc tgtttctctg gcgcaatgcc
    60181 gacacggtag tgattggtcg tgcgcagaac ccgtggaaag agtgtaatac ccggcggatg
    60241 gaagaagata acgtccgcct ggcgcggcgc agtagcggtg gcggcgcggt gttccacgat
    60301 ctcggcaata cctgttttac ctttatggct ggcaagccgg agtacgataa aactatctcc
    60361 acgtcgattg tgctcaatgc gctgaacgcg cttggcgtca gcgccgaagc ttccgggcgt
    60421 aacgatctgg tggtgaaaac cgccgaaggc gaccgcaaag tctcaggctc ggcctatcgc
    60481 gaaaccaaag atcgtggctt ccaccacggc actttgctgc tcaatgccga ccttagccgc
    60541 ctggcaaact atctcaatcc ggataaaaag aaactggcgg cgaaaggcat tacctcagtg
    60601 cgttcccgcg tgaccaatct gaccgaattg ctaccgggga tcacccatga gcaggtttgc
    60661 gaggccataa ccgaggcctt tttcgcccat tatggcgagc gcgtggaagc ggaaatcatc
    60721 tccccggaca aaacgccaga cttgccaaac ttcgccgaaa cctttgcccg ccagagtagc
    60781 tgggaatgga acttcggtca ggctccggca ttctcgcatc tgctggatga acgctttacc
    60841 tggggcggcg tggaactgca tttcgacgtt gaaaaaggcc atatcacccg cgcccaggtg
    60901 tttaccgaca gtctcaaccc cgcgccgctg gaagccctcg ccgggcgact gcaaggctgt
    60961 ctgtaccgcg cggatatgct gcaacaggag tgcgaagcgc tgctggttga cttccaggaa
    61021 caggaaaaag agctacggga gttgtcggca tggatggcag gggcggtgcg gtagttaccc
    61081 acccatgcgg gtaactttct cttcgatttg ccggattttt tccggcattt cttgcgcaat
    61141 gtggcgaaac gcctcgctga tacgcggatc tctggcgacc gtttgccaga actgctgcgc
    61201 cagcgggatc gccgttaacc atgcgctttt actgatgtta agatcaaact tcacctcaat
    61261 ggcagcatca cgcagcattc cggcgctgtt tggcgcatag gccatcggca gcatgtcgta
    61321 gacgggtgtc agcgcaaatg gtggttcaga taaataaaat gataaattgc ctgcgtgcat
    61381 atcgctgttg gcgataagtc gcccaaacgc ccagatcact tctgtttgcg ccacgctctg
    61441 gtgagtgaca agttgttgct cacacaaatg ccgcattgcc tccggccacg atcccggaga
    61501 agagataaac tcactttgca ccgcctccag cgacacaatg ggcaagcgac catcgttacc
    61561 tttgcagtca aagcgttccg cttccaggaa tacctgcctg ttacttgtta caagcaccgt
    61621 tgactcgatg gcgtggatcc cgccgtcacg caggatttgc gcggcaatag attcagcaat
    61681 tagcaggtcc ccccaacgtt ggctgactgc ggtttgctgt ggcacggtga atttcaccaa
    61741 cacatgttta ttgcctgacg gcgtttgtgc atagcaggta aattttggct gctcgccgcc
    61801 cgcagaagaa cccacaattt ctccagccag agcatcgctt gccaactgtt cgtaacgggt
    61861 gagtttttga tccaaaggaa tttccgcagg gcgttgtgca gtaatccatc gctgataatt
    61921 cccctccccg accaaccaac cgccagtata ttcaccgtta aatacggtca gggcgtagag
    61981 cacatcttct tcctgccaga gacgtatatc atcagtcaga ttcagttgcg cggctaactt
    62041 tctgccccac gcgcgcccta aaaagccctg cggtcggaga tcggtcaaat accagggcaa
    62101 accatcaaac cactgttcgt cgccatctgc gcctgttacc agacaacttc cctgtggcca
    62161 gcacaaccgg atgtcggcga atttatgcgc ctttccggca tcgtccaccc gccagacggg
    62221 aatacgctca attccgcgat aaggacgcag cagtacatat cgcgttgccc gtgctttacc
    62281 aaagcgaatc acccgatttt ctctggcaac aaggcgtgag aacgtcgcct gactgattgc
    62341 cagacgctgg cgcaattccg gggcagaacg cggcccttgc agtaaaagat cggtcagttc
    62401 gctcattaat gaatagattc gtgaatagat acttgaatag atttattaac atatttcact
    62461 gaaaagtata gcgaaaatat tcaagctgga gagataaatg aataaatact aaaaagccgg
    62521 agcagtctcc cactccggct tcacacgaca atcgcctttc agcaaaacac aattactctt
    62581 tatcgcccag cagaacggat tccagcgcga ttttgatcat gtcgttgaag gtggtctgac
    62641 gctcagcggc agtggtctgc tcgtgagtgc ggatgtggtc agacacggtg cagatggtca
    62701 gggctttcgc gccaaattct gcagcgacgc cgtagatacc cgccgcttcc atttccacgc
    62761 cgaggatgcc gtatttttcc atcacgtcga acatttcgcc gtccggagag tagaacaggt
    62821 cagcggagaa caggttacca acgcgagcat caacgcccag tgcttttgcc gcgtctaccg
    62881 cgttacgcac catgtcgaag tcagcgatag cggcaaagtc atggtcttta aaacggatgc
    62941 ggttaacttt ggaatcggtg caggcaccca taccgataac gacgtcgcgc agttttacgt
    63001 gcggcagaac agcgccacag gaacccacgc ggataatttt cttcacgccg aaatcagtga
    63061 tcagttcttt ggtgtagatg gagcaggacg ggatacccat accgtggccc attacggaaa
    63121 ttttgcggcc tttgtaagta ccagtgaagc ccagcatacc gcgaacgttg ttcacttcac
    63181 gggcatcttc aaggaaagtt tcagcaatat acttcgcacg cagcgggtcg cctggcatca
    63241 aaactacgtc agcaaaatcg cccatttctg cattaatgtg tggagtagcc atcgttttat
    63301 cctttttgtg acatattaaa ggcggagtca ctgctccgcc caaatccatc agaacatggc
    63361 tttgccatat tccatatcag aagtaccaaa atattttgcc agagtctggc cgatatccgc
    63421 gaaggtttca cgatgaccca gcgaacctgg tttcactttc gggccgtaaa ccagtaccgg
    63481 aatgtgttca cgcgtgtggt cagtaccggt ccaggtcggg tcacaaccgt ggtcagcagt
    63541 gagaatcaga atatcgtcat cgcgcagcaa agacatcagc tccggcagac ggcggtcgaa
    63601 cagttccaga cccgcagcat aaccggcgac gtcgcggcgg tggccccagg aagagtcgaa
    63661 gtcaacgaag ttggtgaaga cgatggtgtt atcacccgct tctttcatct ctttgatggt
    63721 ggcgtcaaac agcgcgtcca gcccggtcgc tttcactttt ttggtgatac cgcagttggc
    63781 atagatgtct gcaattttac cgaccgaaac cacctggccg tgtttttcat caaccagttt
    63841 ctgcagcacg gtcggtgctg gcggctcaac agccaggtcg tgacggttac cagtacgctg
    63901 gaagttaccg gctttgtcgc cgataaacgg acgagcgata acacgaccga tgttgtagcc
    63961 gccgttggtc agctcttcac gggcgatttc gcacagctcg tagagtttat ccaggccaaa
    64021 ggtttcttca tggcaggcaa tctggaacac ggagtcagcg gaggtataga aaatcggctt
    64081 gccggttttc atatgctctt cgcccagttg atccagaatg accgtaccgg aagagtggca
    64141 gttaccgagg taacccggca gattagcgcg ttcgaccagt ttatccagca actcttgcgg
    64201 gaagctgttt tcgtgatcgg agaagtatcc ccactcaaac agaaccggca caccagcaat
    64261 ttcccagtga ccagacgggg tgtctttacc ggatgacatt tcgtgcgccc atgcgtacgc
    64321 gccgataact tcagcgttgc catccattcc cgccggaatg aaaccggtag aaccttcgtg
    64381 tgctttcgcc agcccaagac gggtcagatt tggcagattg agcgggcctt tacgaccgtg
    64441 gtcagcttcg cctttggcac aagcttctgc gatatgaccc agggtgtcag ccccgacgtc
    64501 accaaagcgt tctgcatctt ctgtagcgcc gatgccgaat gagtccagca ccataataaa
    64561 tgcacgtttc atatgttctc cgtactcagt gcttcaaatt taaatgatcg gatcagtata
    64621 ccgttattcg ctgatgcggc gatagacagt tggtgtgctt tccggtgctt tatcggcaag
    64681 tttaattgcc gctttcaccg ctttcgccgc ttcctgccag ctgttttcgt ctttcgcgtg
    64741 gataactgcc agcggacgct gaccgtctac ctggtcgccc agacgcgcca tatcagtaaa
    64801 gccgacgctg taatcgatgg tgtcagatgc ctgacggcgt ccgccgccca ttgcaaccac
    64861 tgccatcccc agtgcgcggg tatccatttc actgacaaac ccttcggtat cagcatagac
    64921 tgctttcgtc agcatcgctg tcggcagata cttcgcgtag ttctcaacga agtcggtcgg
    64981 gcctttttgt gccgcgacca tacgaccaaa gacttctgcc gctttaccgt tgtccagcac
    65041 cgcctgcaat ttcgcgcgcg cttcggcgtc atttttcgcc agtttgccgg agatcagcat
    65101 ctccacgcac agtgccatcg tgacatcaaa cagacgcggg ttacgatgtt cacccgtcag
    65161 gaactgcacc gcttcacgaa cttcaaccgc gttacctgca ctggaggcca gtacctgatt
    65221 catatcggtg agcagcgcgg tggtgcgcac gccagcgccg ttagccacgc caacaatcgc
    65281 ttcggcaagg gcttcagaga gttcgtaggt cggcataaac gcgccgctac ccactttcac
    65341 gtccatcacc agcgcgtcca gaccttccgc cagtttcttc gccagaatag aggcggtgat
    65401 cagcgggatt gaatccacgg ttgcggtaat atcgcgggtc gcgtagaaac gtttatccgc
    65461 cggagccagt gagctggtct ggccgataat cgccacgccg acgtctttaa taatttcgcg
    65521 gaaacggttg tcatccggga aaatgtcgaa gccagggatg gattccagtt tgtcgagcgt
    65581 accgccagta tgaccgaggc cgcgaccgga gatcatcgga atatagccgc cacaggcagc
    65641 gaccattggc cccaacatca gcgaagtcac atcgccgaca ccgccggtcg agtgtttatc
    65701 aacaatcggg ccattcagat gcaggctttt ccagtcgaga acggttcctg aatctcgcat
    65761 cgccatggtc agcgagacac gctcaggcat tgtcatatcg tggaagaaaa tggtcatcgc
    65821 gagggcggca atctgccctt cggagatagt gttgtcgcga atgccgttga taaagaaacg
    65881 aatttcttca tcactcagcg catgaccatc acgtttttta cgaataattt cttgtgcgag
    65941 aaacaaggta acctcccgtg gaaaagagac gaggtaatcg gggaaccgga tgagcatcgc
    66001 tgcatcatcc ggcaaatcaa gccttagtag ctgctggcgc tcttaccgtc gccgtggccc
    66061 agagctttca gcaggcttgc cagcaagctg gaagcaccaa agcggtagtg acgcgcatca
    66121 gcccagtcag caccgaacag ttcatctgca atggcgagat atttctgcgc atcttccgca
    66181 gtacgcacgc cgcctgccgg tttgaaacca acggtttttt ctacgcccat atcgcggatc
    66241 acttccatca tgatgcgcgc gctttccggc gtcgcattca cagccacttt accggtagag
    66301 gttttgatga agtcagcacc cgctttgatg gagatttcag acgctttacg gatcagcgct
    66361 tcgtctttca gttcgccggt ttcaataatc actttcagca gtacgttcgc cgcagcgcaa
    66421 gcctctttac aggctttcac caggtcaaaa ccaacctgct cgttacctgc catcagcgcg
    66481 cggtacggga acaccacgtc aacttcatcg gcaccgtagg cgattgccgc acgggtttct
    66541 gccagcgcga tttcgatgtc gtcgttaccg tgtgggaagt tagttaccgt agcgatacgg
    66601 atttccgggg tgccctgctc tttcagagtt ttgcgagcaa tcgggataaa gcgaggatag
    66661 atacagatag cggcggtatt gccgaccgga gttttggcct gatgacacag tgcgatcact
    66721 ttctcatcgg tgtcgtcgtc attcagggtg gtcaggtcca tcaatttcag tgcacgcagg
    66781 ctgcttgctt tcagatcagt catttcattc tcctggcttg tcgccaataa aattcacctt
    66841 gcgagtttgt tagtattcta acatctactc cgcaacacac ttcgatgtac atcacaatta
    66901 aggaaatcta cttacaagtt tgcatcactg taatgcgatc tggttcaaat aattcacttt
    66961 caaatgaatg cgtcagtggt ggcaaacgca tcaggatcaa agtgaacatc acgaaacttc
    67021 ttacaatggc gcatcacctt cggcataaaa ggaaaagaag atgcccactt ctcatgaaaa
    67081 tgcactgcaa caacgttgcc agcaaattgt caccagcccg gtacttagcc cggagcagaa
    67141 gcgccatttt ctggcactgg aagcagaaaa caatctgcct tacccacagc tgcctgccga
    67201 agcccgccgc gcgctggatg agggggtaat ctgcgatatg tttgaaggtc atgcgccgta
    67261 caaaccgcgc tatgtcttac ccgattacgc tcgttttctg gcgcacggtt ccgaatggct
    67321 ggagctggaa ggcgcgaaag accttgatga cgcactctct ctgctgacca ttctttacca
    67381 ccatgtaccg tcggtcacat cgatgccggt ctacctgggg caactggatg cgttgttgca
    67441 accgtatgtt agaattctaa cacaagacga gatcgatatt cgaataaaac gtttctggcg
    67501 ttacctcgac agaaccctgc cagacgcctt tatgcatgcc aatatcggtc cgtctgattc
    67561 gcccattacc cgtgcaatat tacgtgcaga cgcagagctg aagcaggttt caccgaacct
    67621 gacctttatc tacgatcctg atatcacccc tgatgacctg ctgctggaag tggcgaaaaa
    67681 cgtctgtgaa tgtagcaaac cgcacatcgc caacggtccg gtgcatgata aaattttcac
    67741 aaaagggggc tacgggattg tgagctgtta caactcactg ccgctggcgg gtggtggcag
    67801 cacgctggta cgccttaacc tgaaagccat tgccgagcgc agcgaatcgc tggatgactt
    67861 ctttacgcgc actctaccgc actactgcca acagcagatc gccatcatcg atgcgcggtg
    67921 tgaattcctc tatcaacaat cacacttctt tgagaatagc ttcctggtga aagaagggtt
    67981 gattgatcct gaacgttttg tgccgatgtt tggcatgtat gggctggcgg aagcggttaa
    68041 cttgctgtgt gaaaaagaag ggattgccgc acgctacggt aaagaggccg ccgcaaatga
    68101 agtgggttat cgcattagcg cgcaactggc ggagtttgtc gccaataccc ccgtgaaata
    68161 tggctggcaa aaacgcgcca tgttacacgc acagtcgggg atcagttccg atatcggcac
    68221 cacgccgggc gcgcgtttgc catatggtga tgagccagat ccgattaccc atctgcaaac
    68281 tgtcgccccg catcatgctt attattattc cggcatcagc gacattctga cgctcgacga
    68341 aaccatcaaa cgtaatccgc aggcgctggt acagctttgc ctcggtgcct ttaaagccgg
    68401 aatgcgtgaa tttaccgcca atgtcagcgg taacgatctg gttcgcgtta ccggttatat
    68461 ggtgcgtttg tcggatttag aaaaatatcg cgccgaaggt tcacgcacca acaccacctg
    68521 gctgggagaa gaagccgcac gcaacactcg tattctggaa cgccagccgc gcgtgataag
    68581 ccatgaacag cagatgcgct ttagtcagta agattatccc cttctcctgc gttgacgggc
    68641 caggcagtcg tctggctctg tttttgcagg gctgcaatct gcgctgcaaa aactgtcaca
    68701 atccgtggac gatgggacgt tgcaatgact gtggggagtg cgtgccacag tgtccgcatc
    68761 aggcgttgca gattgttgac ggcaaagtgg tgtggaacgc tgtggtttgc gagcagtgtg
    68821 atacctgcct gaagaggtgt ccgcaacatg ccacgccaat ggcgcaatcc atgagcgtgg
    68881 acgaagtgct tagccatgtc cgcaaagcgg tgctgtttat tgaagggata acggtaagca
    68941 gcggcgaagc cacgacccaa ctgccgtttg tagtggcgct gtttactgct atcaaaaacg
    69001 atccgcaact gcgccacctc acctgcctgg tggacagtaa cggtatgttg agcgaaaccg
    69061 gctgggaaaa attactcccg gtgtgcgacg gcgcaatgct cgatctcaaa gcgtggggga
    69121 gcgaatgtca tcagcaatta accggacgcg ataatcagca gattaagcgc agcatctgtt
    69181 tgctggcaga gcgcggtaag ctggcggaac tgcgtttgct ggtgatccct ggccaggtgg
    69241 attatttgca acacatcgaa gaactggcgg cgtttatcaa gggactcggc gatgttccgg
    69301 tacgcctgaa cgcgtttcat gcccacggcg tgtatggcga ggcgcaaagc tgggcgagcg
    69361 ccacgccgga agacgttgag ccgttggctg atgcgttaaa ggtgcgcggg gtgagccggt
    69421 tgatatttcc ggcgctctat ttgtgacatg ccggatacgg cctacggttc ggcacagact
    69481 tgtaggcatg ataagacgcg acaagcgtcg catcaggcat tatgcgccga ctgccggatg
    69541 cggcgtgaac gccttatccg gcctacggtt cggcacagac ttgtaggcat gataagacgc
    69601 gtcagcgtcg catcaggcat tgtgcgccaa ctgccggatg cggcgtgaac gccttatccg
    69661 gcctacggtt cggcacagac ttgtaggcat gataagacgc gtcaagcgtc gcatcaggca
    69721 ttgtgcgcca actgccggat gcggcgtgaa cgccttatcc ggcctacggt t
//
LOCUS       DAPOXO010000015        66306 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPOXO010000015 DAPOXO010000000
VERSION     DAPOXO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 66306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66306
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.015"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..625)
                     /gene="upp"
                     /locus_tag="ROH59_001254"
     CDS             complement(<1..625)
                     /gene="upp"
                     /locus_tag="ROH59_001254"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDX4803768.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            950..1987
                     /gene="purM"
                     /locus_tag="ROH59_001255"
     CDS             950..1987
                     /gene="purM"
                     /locus_tag="ROH59_001255"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDX4803769.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLKLIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            1987..2625
                     /gene="purN"
                     /locus_tag="ROH59_001256"
     CDS             1987..2625
                     /gene="purN"
                     /locus_tag="ROH59_001256"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDX4803770.1"
                     /translation="MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLE
                     RARQAGIATHTLITSAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     TEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
     gene            2797..4863
                     /gene="ppk1"
                     /locus_tag="ROH59_001257"
     CDS             2797..4863
                     /gene="ppk1"
                     /locus_tag="ROH59_001257"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HDX4803771.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQSE"
     gene            4868..6409
                     /gene="ppx"
                     /locus_tag="ROH59_001258"
     CDS             4868..6409
                     /gene="ppx"
                     /locus_tag="ROH59_001258"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HDX4803772.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(6448..8691)
                     /gene="pdeF"
                     /locus_tag="ROH59_001259"
     CDS             complement(6448..8691)
                     /gene="pdeF"
                     /locus_tag="ROH59_001259"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HDX4803773.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGIALGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDSRLISQRLFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFAI
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLHIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRS
                     PVNHIYLLLGELNTVAELSIVTNVPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELISPDSFLPVAHEFGLSSSIDMWVIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLAKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMRVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
     gene            complement(8873..9025)
                     /locus_tag="ROH59_001260"
     CDS             complement(8873..9025)
                     /locus_tag="ROH59_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803774.1"
                     /translation="MSHAVDGTYIKAQQDKMVNSSLCKEASVNTYFNVMEVNLIIYND
                     DVIMMS"
     gene            9043..9234
                     /locus_tag="ROH59_001261"
     CDS             9043..9234
                     /locus_tag="ROH59_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HDX4803775.1"
                     /translation="MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHH
                     QSKKEAQQSTLSVESPVQR"
     gene            9536..10054
                     /locus_tag="ROH59_001262"
     CDS             9536..10054
                     /locus_tag="ROH59_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDX4803776.1"
                     /translation="MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNAQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
     gene            10070..10609
                     /locus_tag="ROH59_001263"
     CDS             10070..10609
                     /locus_tag="ROH59_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HDX4803777.1"
                     /translation="MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQRQH
                     DEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATADKKRDQSYE
                     DELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSDSWFN"
     gene            complement(10804..11301)
                     /locus_tag="ROH59_001264"
     CDS             complement(10804..11301)
                     /locus_tag="ROH59_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 family protein"
                     /protein_id="HDX4803778.1"
                     /translation="MIWAFAKAYWKQLVIMAMLAVLVISGVVAWNAHGSRQYDAGYAQ
                     AQEDQKQADDKARSQRDQEKTQIEREAQSRIDVARVDAEHANAAADSLRAELDKTKRL
                     AEHYTGSFPTGTPASKVIGVLADMLEESNRVYNATAAEAEKYRIAGESCEQQYDSLKK
                     QKSWH"
     gene            complement(11298..11927)
                     /locus_tag="ROH59_001265"
     CDS             complement(11298..11927)
                     /locus_tag="ROH59_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 19 protein"
                     /protein_id="HDX4803779.1"
                     /translation="MEIKQFQRAAGISEALAARWFSHITSAMKEFGISKPEDQAMFIA
                     QVGHESGGFNRLQENFNYSVTGLANFVRAGRLTQGQANALGRRAGEPPLPLERQRAIA
                     NLVYSKRMGNNASGDGWNYRGRGLIQITGLNNYRDCGNGLKVDLLESPELLAQDEYAA
                     RSAAWFFASKGCMKYTGDIARVTLIINGGRNGIDDRRARYITASKVLAV"
     gene            complement(11917..12225)
                     /locus_tag="ROH59_001266"
     CDS             complement(11917..12225)
                     /locus_tag="ROH59_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDX4803780.1"
                     /translation="MVTHEFFLLITNAVICTGIAIRVVTFRRNGSQHRRWGGWLAYFL
                     IVAAASIPVRVVYAIWLRTPMAVDLSEVIINAVMLAAVIKTRGNVVHIFKISRSKHGD
                     "
     gene            complement(12212..12616)
                     /locus_tag="ROH59_001267"
     CDS             complement(12212..12616)
                     /locus_tag="ROH59_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803781.1"
                     /translation="MSFQLTNETSNQWLSVSSLAAVIAGVPPEVALGALAGAVIFVTS
                     AVEYPIRRRVLLSMLSFLCGLLFYKPAASILIGIASLIPTITQDSFEKGIVFSAGAFV
                     SAIVAVRIGIWLYHRSDNPRELIPGRKDDGNA"
     gene            complement(12689..15151)
                     /locus_tag="ROH59_001268"
     CDS             complement(12689..15151)
                     /locus_tag="ROH59_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HDX4803782.1"
                     /translation="MTVSTEVDHNEYTGNGVTTSFPYTFRIFKKSDLVVQVSDLNGNV
                     TKLVLDAGYTVTGAGTYSGGAVVLPSPLAAGWRITIERVLDVVQETDLRNQGKFFPEV
                     HEDAFDYLTMLIQRCFGWFRRALMKPSLLAKYYDAKQNRISNLADPSLEQDAVNNRSM
                     RNYVDAAIAGVVGGFGWFIQYGSGAVYRTLQDKMRDGVSIKDFGAQNGILNDNKEAFT
                     KSLHSFSSVFVPEGVFNTSLVSLSRCGLYGTGGGTIKQYDRDGNHLVFNMPDGGMLST
                     LTIMGNKSDDSVQGHQVSFSGGHDVSVKNIRFTNTRGTGFSLIAYPNNGIPSGYIVRD
                     IRGEYLGFANNKKAGCVLFDSSQNTLIDGVIARNYPQFGAVELKTAAKYNIVSNVIGE
                     ECQHVVYNGTETETAPTNNIISSVMANNPKYAAVVVGKGTGNLISNVLVDYSESDAKQ
                     AHGVTVQGNNNIASNILMTGCDGKNESGDLQTSTTIRFLDAARSNYASIFPMYSSSGV
                     VTFEEGCIRNFVEIKHPGDRNNILSSASAVTGISSIDGTTNSNVVHVPALGQYVGTMS
                     GRFEWWVKYFNLANQTLVSADKFRMLAEGDVSLAVGGGISSQLKLFNSDNTKGTMSLI
                     NGNIRISTGNSEYIQFSDSAMTPSTTNTYSLGLAGRAWSGGFTQSAFTVLSDARFKTA
                     PEVIDEKILDAWERVEWVSYQYLDRIEVKGKDGARWHFGAVAQHVISVFQNEGIDVSR
                     LAFICYDKWNETPAEYRDVTEEEHSAGVYPLIQTKVLVREAVEAGECYGIRYEEALIL
                     ESAMMRRRVKKLEEQVLQLTGN"
     gene            15348..15605
                     /locus_tag="ROH59_001269"
     CDS             15348..15605
                     /locus_tag="ROH59_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803783.1"
                     /translation="MQQYHYPLEEGFTERIHTPGGVRSLVEGSHLMKLLRDLDKDGFN
                     VDGPLAELTALINYVTSSQMSMRDLQTHLDYCAEQLRKQTR"
     gene            15923..16579
                     /locus_tag="ROH59_001270"
     CDS             15923..16579
                     /locus_tag="ROH59_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor Ant"
                     /protein_id="HDX4803784.1"
                     /translation="MNAQLIPVFNGTIANETTLLVNARDLHTFLGVGKRFASWITERI
                     AEYGFVENQDYILVSPNREIKGRGGDRRSKDYHLTLDTAKETAMVERNEKGRQIRRYF
                     IECEKRLRQQETKVEKVLSGFMPAIMEAIKLEDKKEYSAPLKPGYRSLIHSPSGVLGL
                     TENSLLMNLLNQLQEDGHDVSGAAAELTTMFCYIVGVSKCLRDIQTHAEYINDKAGFF
                     "
     gene            complement(16651..16812)
                     /locus_tag="ROH59_001271"
     CDS             complement(16651..16812)
                     /locus_tag="ROH59_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane anchored protein"
                     /protein_id="HDX4803785.1"
                     /translation="MKKAFAALFVLLSLVASTQAFAGRCQHDSDTAADGSRCGGRSAD
                     SRPGGGGIR"
     gene            complement(16911..17543)
                     /locus_tag="ROH59_001272"
     CDS             complement(16911..17543)
                     /locus_tag="ROH59_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803786.1"
                     /translation="MRTNTTRKAMPYIIPEADFDRKLNMSEKNTSHTESYLAKGVVDF
                     VLPGFTTPYGYRLVKSCNGDHYRMITTSDTPETVYAVKLIFREDIVEAKRTCTQIMVW
                     RTPNVIHDRAVHGLPQIFFQFFLEQYAIVVSDEQQTIDGRRFWERMISWAINTPGYNV
                     YVSDGSEEDRPLSFMTSWDDFYSQWADFCWGSDKDVHTHRLLVISKDKLH"
     gene            complement(17690..18385)
                     /locus_tag="ROH59_001273"
     CDS             complement(17690..18385)
                     /locus_tag="ROH59_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HDX4803787.1"
                     /translation="MTATKSTSIFSFESQADIRVIVINGEPWFIASDVCRAIGIANHR
                     DAVRKLDDDEKGVASTDTPGGEQESIIISESGLYTLILRCRDAVTPGTIPYRFRKWVT
                     GEVLPQIRRTGSYIKNSLPQEERIKMVADQVANATASAVMQAMKIENKTYSAPLKPGY
                     RSLIHSPSGVLGLTENSLLMNLLNQLQEDGHDVSGAAAELTTMFCYIVGVSKCLRDIQ
                     THAEYINDKAGFF"
     gene            18772..19077
                     /locus_tag="ROH59_001274"
                     /pseudo
     CDS             18772..19077
                     /locus_tag="ROH59_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001428824.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(19165..19461)
                     /locus_tag="ROH59_001275"
     CDS             complement(19165..19461)
                     /locus_tag="ROH59_001275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803788.1"
                     /translation="MDIKEFSELERRYEQAKTNRAIGAFIGGGGVFALLADFLWDVAN
                     PISIGVLIGGGLVFFAVCHEQVRSSLRKLDEECYLKYGKSYSQSFHEIFKDKYN"
     gene            complement(19539..20387)
                     /locus_tag="ROH59_001276"
     CDS             complement(19539..20387)
                     /locus_tag="ROH59_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803789.1"
                     /translation="MKKINLFGIVLSIVAVNPTAASSLQCNKDNFDACKTCEQLSKAI
                     DLKEPNRGDYYRGALWNGLYVSYVINCPVVAEKLLSHGAIPSYGGYMGSMGAVLTGKW
                     PHNNESINLSWADLLIKHGFDVNKHTGHYKSATEVWAIDKKQIEYKSVFDKLIQSSEV
                     KPLDPSRNLEWCASEGYRSVVVYSLNSCIENAIKRLDDGVSSASDISSAAVNSCTSDV
                     ENFNKHLSCKSAVKENSDKEKRNVYQLLTSDSQMNKNVMDMLKERNIETVLEFRAENR
                     AMKTSQ"
     gene            complement(20389..23778)
                     /locus_tag="ROH59_001277"
     CDS             complement(20389..23778)
                     /locus_tag="ROH59_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004243853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803790.1"
                     /translation="MPIYEQDPKELLGEGIQQIAAPDDSNFYMETPSLLSAVNPFTSD
                     QRVQRSRQAAFRIDNTLGSFIASAPFSQFDRVEGYNPFDNDAADIKGYEDFADSFINS
                     GSHEETMAIKHRIDQQRADMEYNSGLGFAGTVSSVAMRLADPFNAISMFIPFGAVVRG
                     GRIAETAGRFALANAAGSVASEAALQATQEARSPMESVSNVVVDALVGGILGAGAQLL
                     AGPSAREAVVNSVGNHLRGMDSPQSIGAAQVFNTTLDQEQLAGLGLANKTLSVTPAGR
                     LAQSPSLVSRQINQQLAENNYFFAKNDEGLATFTAVETKIKQYDAMLYKQMEATRDAY
                     QQYSKSVSARGVKRMNFIDFNEAVGMAMRRGDQSDIPEVSQAAARIRPIFETTKARMQ
                     ELGILPEDIDVVTAKSYLPRIYKFDKILSDRTEFRGRIANWIQGISAKGADKAGQRIE
                     KINSLLKTAEESAPRADALASEIAEAEKWSGKKILLMEELDKRNKLISQETDTQARLT
                     RIEKELAETSSEKLQARMMKESSDLKTRLDDIAQAKSELPVYQRHMELLDNPRKYRSE
                     LRRLQKRANSTTRLNASRERALKQMEPLSREEAEDAADEIVNKIIGAPSGLVPADIIP
                     ERLVGRAGFTKSRTLLIPDERIEDFLESDVNYIMESYLRQVAPEIELTAQFGRKDMGE
                     QIRQVSEEYTRLIKEAKTPKRRAALEKQREADIRDITAMRDRLLGTYGAPQDPRSFFV
                     RAGRVARNINFLRLLGGMTVSAATDLMRPMMQHGLRKSLGPMVSMLKNMDSVKIATRD
                     LREMAVGLDYVLSTRTKAIADLTDPYSRRSAAERGLNWMTQKFGNWTLMNQWNSALKS
                     WSGMIVQSRILDAARQVSAGGTLSKSEMRKMAQVGINEDVLRRIGEQFGKHGEDMDGL
                     LTGHSHLWDDRFAREIFQSAVLKDVDSVIVTPGVGDTPLFFSKEGWKMITQFKTFIFA
                     QHNRVLVSGIQQGDAAFYLGALGTIALGSMVYMMKQKLSGRDIDYSWNNLVKEGIDRG
                     GMLGWLSEPLNTVENISGGRFGLGAMFGAPPVSRFQSRNAIGALLGPTFDLGGDAATV
                     ANGVLNGEFDSQQTHAVRKMLPFQNLWAISPLLNKVEEQMK"
     gene            complement(23778..26525)
                     /locus_tag="ROH59_001278"
     CDS             complement(23778..26525)
                     /locus_tag="ROH59_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803791.1"
                     /translation="MPVVPTTSGRQVQSRGVQTGGFQTFDVPQAGQVLANVADQYAVA
                     YGEARQKANVAMAQEALLQFNQFADDQINNPENGLISKQGKNALGQSDAVMKNMQERA
                     QALLGSIPESEERNKLSFQLQQSMQSYYNQARRYEVGQFQQFQDQTYLSGNALAVTQS
                     AGLYSDNQAFVDLAKQRFESIDQYADAHGLPDEWRVQQKTQLKEQMGQQAWIGNIAQK
                     YNEFLQVNGEPGDLDGVSRAISHGNSLDARGLRNNNPGNIEASKSNPWEGQIGSDGRF
                     ATFATPEHGIRALGKNMLSYQRQGYDTVSEIVNRYAPASDGNNTDAYIRALCGELGVG
                     ENDQLDISNPKTLAALCAGIIKHENGSMPYSTEQLETGISAALGLTNLDSPKRYTGNA
                     AFDAMSPQMQIQALRQANELRNQYRQQYADQLSTVVKDAYSALDEGLKPEKLPSEDDF
                     IRANGPRIGAMKWKDMQAQIQYGGVIGAAKDLTPEGRQDILERLRPQDPNAPGFAANQ
                     QRWEKMQAKFKEMDREWEIQQGRNRFVSSMQNNFPLDPNDKNNQAAVDRYFAQDIAPS
                     FSISDPQSINTLVTVTTKSGMIPTQIKTMLNSGATSRDPALVVPMAKFYGQLFDNNPA
                     AAATLDKSTMAFYGKVYDYSRAGVPEDKAVDMAYSQVFQQDDRMKQMLSTAMRDKKYV
                     AARATAAQNNASSLTSFGSWSPDITDPGKSNAAYQRDYQTIYDANFVQTGGDAEQAEK
                     MTNAMIRTTWGVSTVNGKAEVMKYAPEALYGVNNGAGNWIQGQWEQEKRELKSKSFGG
                     PRSDTDLILVSDGLTARDRSYAVMVLQPDANGAIEPRNYIGENGLPVRFKPDQLTSPM
                     YRQTIQFQQQRVDEARVRREGNPLPQFSNKDGYTPPDLTKPFGYGSANYLPSNIYAGG
                     K"
     gene            complement(26525..27091)
                     /locus_tag="ROH59_001279"
     CDS             complement(26525..27091)
                     /locus_tag="ROH59_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803792.1"
                     /translation="MCNPAIALVAVTVASTAASMYSQSKQAKYQSAIADRNAEIAEAQ
                     AQDSINRGNIEADQRRREMRQRSGTAAATMGATGAELSSGTALDVFADNAQFGTLDAL
                     TTVNNAQREAYGYQVQGMNAQAQGAAAQSAAKSSMTSTLLTAPLKAYGAYKLGSGSIN
                     PISKQGNTPMLSNSGFMNSDSRFKIGGY"
     gene            complement(27091..27555)
                     /locus_tag="ROH59_001280"
     CDS             complement(27091..27555)
                     /locus_tag="ROH59_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803793.1"
                     /translation="MIDVQIIPATEEHLQMILPDVRQADIDELYAVSLMTTEDALRVG
                     LRTATMAWSGFANGELVTMFGVSPASMIGGNGTPWLVGTSRIEKYQKTFLRHCRPVLQ
                     QMLAVYPRLENYVDERNHVAKAWLHWLGFRLEEAAPYGALGLNFHRFHMERK"
     gene            complement(27555..30026)
                     /locus_tag="ROH59_001281"
     CDS             complement(27555..30026)
                     /locus_tag="ROH59_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803794.1"
                     /translation="MAISWIQPSFAGGEIGPSLYGRIDMAKYQVALRKCDNFIVRQYG
                     GVENRPGTRFVGAAKYPNRKCRLIPFQFSTVQTYALEFGHQYMRVIKDGALVLNSSNV
                     IYEISTPYTEADLFRIKFTQSADVLTLVHPAYPPKELRRYAHDNWQLVDVVTKNGPFE
                     DINIDESVTVYASASTGTITLTASASIFGAEQVGKLFYLEQPAVDSVPVWETSKSTSI
                     GDIRRADSNYYRAVTAGKTGTLRPSHTEGTSWDGWGGSGDDDTGIEWEYLHSGFGIAR
                     ITAANGTTATAEVISYIPSQVVGEDNASYKWAKYAWNSVNGYPGTVVYYQQRLYFAAS
                     TAFPQTIWASRTGDYKDFGKSNPTQDDDRIIYTYAGRQVNDIRHLIDVGSLVALTSGG
                     EYVITGDQNKVLTPSSFAFSSQGSNGSSNVPPIAVANIALFVQEKGSVVRDLAYSFDV
                     DGYQGNDLTILANHLFQKHSIVDWCFSIVPYSSAFCIRDDGKLLVMTYLRDQQVFAWA
                     PQSSTGKYESTCSISEGNEDAVYFVVNRTVNGQTVRYIERLSSRLFTSDEDAFFVDSG
                     LSYDGRNTSDRTMTITGGSGEWDYHAEYTISVSGGAYFTSSDVGAQLQFPYTGTDPDT
                     GDEVSKELRCDIISVTSNTAVVVRANRNVPPSLRNVATTNWQMARRTFGGLSHLEGQT
                     VNILSDANVEPQKVVSGGAVTLESPGAVVHIGLPITAEFETLDININGQETLLDKKQV
                     IPSVTLVVNASRGIWATTPGGKWYEYPQREFEFYDDPVDDATGKVEVKLDSNWGKNGR
                     VKIRQLDPLPLSVLAVIPRLTVGGF"
     gene            complement(30026..30631)
                     /locus_tag="ROH59_001282"
     CDS             complement(30026..30631)
                     /locus_tag="ROH59_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803795.1"
                     /translation="MASVVEICNRALSNIGNSRSINSLTEASKEAGECSLHFEACRDA
                     VLSDFDWNFATKRVALADTSNPPPDWEYAYQYPSDCLRITEIMLPGVRNPTAAMRVQY
                     EVGVDTNGTGKLIYTDQPQAWLKYVSRVTDVNMFDAIFMEALAWRLAAAINMALTGNA
                     DLGTFALNMYNRVILSAGSHSQNESQEPQPPVDEFTIARLS"
     gene            complement(30631..30954)
                     /locus_tag="ROH59_001283"
     CDS             complement(30631..30954)
                     /locus_tag="ROH59_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803796.1"
                     /translation="MELVNLKTGTDSYQDESGETRTRDEYPWGLCITLNNDTLNKLKA
                     QPQGVGTEVMITAKAVIRGLSARETDDGVNRSADLQITDMAIAPVSGDVEKSAAETLY
                     GNGGE"
     gene            complement(31005..31340)
                     /locus_tag="ROH59_001284"
     CDS             complement(31005..31340)
                     /locus_tag="ROH59_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803797.1"
                     /translation="MSGEKPRYRVLRLSHIHNTLWPEGAEIEYEGEPGSALEPVNDAA
                     RQAKAKVAGKESMAATSTKIINDVSDDGELDKLREEYELLFNEKPHHNAKAETLREKI
                     ADKRKELGV"
     gene            complement(31351..31788)
                     /locus_tag="ROH59_001285"
     CDS             complement(31351..31788)
                     /locus_tag="ROH59_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803798.1"
                     /translation="MITDKLLMFSEAQAVTDTAASTDVIDLGPIDGKRRDIGVGYPLE
                     FWALVNTAAAASGDATVNIQLQTSEDNSSWSTIYDSGALAKATLTAGKRVVSAKVPAG
                     VQRYLRVNYSVATGPLTAGKFTAGINLDVDANTPYPIRSKVTG"
     gene            complement(31840..32826)
                     /locus_tag="ROH59_001286"
     CDS             complement(31840..32826)
                     /locus_tag="ROH59_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803799.1"
                     /translation="MAVKGLTALTLADWGKRVDPNGKVDKIIELLGQTNPILQDMPFV
                     EGNLPTGHRTTIRSGLPSATWRLLNYGVQPSKSTTVQVTDSVGMLETYAEVDKSLADL
                     NGNTAEFRLSEDRAFIEAMNQQMAQTLFYGDSSVNPQQFMGLSSRYSSLSAGNAQNII
                     DAGGTGTDNTSIWLVVWGENTVHGIFPKGQKAGIQMEDKGQVTLEDANGGKYEGYRTH
                     YKWDNGLALRDWRYVVRIANIDVSNLSEPSSAANIAKLMVKALHRIPNRGMGRPVFYM
                     NRTVGQALDLQSLEKTSLAISVKETEGEWWTSFRGVPIRETDALLETEARVV"
     gene            complement(32841..33536)
                     /locus_tag="ROH59_001287"
     CDS             complement(32841..33536)
                     /locus_tag="ROH59_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDX4803800.1"
                     /translation="MNLFERLLYRRLCNEQPVDGGAAPAASEPSAPAGDNPAPVGDPS
                     QPEGDKPQPVADGDKPADDKKPENDKQDEKKDGDKTEGAPEKYEFQAAEGVELDTEAL
                     KEFEPVARELNLTNEQAQKLVDAYPKILAGVQQRQAEAWQKTTEQWAADVKADKEIGG
                     DKLISNLSAAQRALDQFGTPELKEYLNTTGLGNHPDLVKTFVKIGKAMSEDGMVTGGN
                     EGQRSAAEVLYGK"
     gene            complement(33539..33835)
                     /locus_tag="ROH59_001288"
     CDS             complement(33539..33835)
                     /locus_tag="ROH59_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803801.1"
                     /translation="MTDYEDDQLKEENARKQRDMAQREIDDICFVMSSEQGRRVVWSV
                     LEKGRVFSAISPMDAMAMAFNEGQRNLALELFQRVMAHCPEQYLKMAKEASEQE"
     gene            complement(33832..35511)
                     /locus_tag="ROH59_001289"
     CDS             complement(33832..35511)
                     /locus_tag="ROH59_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4803802.1"
                     /translation="MAETTKERLNKQFAQLESERQSFEPHWRELSDYINPRGSRFLTS
                     EVNRNDRRNTRIIDSTGTMAARTLASGMMSGITSPARPWFRLATPDPEMMDYGPVKLW
                     LEAVQNRMNDMFNKSNLYQSLPQLYGSLGTYSTGAMAVLEDDEDIIRTMPFPIGSYYL
                     ANSPRGSVDTCFRKFSMTVRQLVQEFGLNNVSESVKSMWESGTYEKWIEVMHSVYPNI
                     DRDTSKLDSKNKPFKSVYYEVGGDNDKLLRESGFDEFPIMAPRWEVNGEDVYGSSCPG
                     MLALGPVKALQLLQKRKSQLIDKATNPPMVAPTSLKNQRASLLPGDITYIDQITGQDG
                     FRPAYLVNPSTADLVADIQDTRQIINSAYFVDLFMMLQNINTRSMPVEAVIEMKEEKL
                     LMLGPVLERLNDECLNPLIDRAFSMMVRKNMLPPPPDAMEGMPLKVEYISVMAQAQKS
                     IGLSSLASTVNFIGQLAQAKPEALDKLNVDQAIDAFADMSGVSPTVIVPQEQVEQARQ
                     QRAQQQQQQQMMAMGMAAAQGAKTLSEAKTSDPSVLSAMANAVSGQGGQSQ"
     gene            complement(35526..35732)
                     /locus_tag="ROH59_001290"
     CDS             complement(35526..35732)
                     /locus_tag="ROH59_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803803.1"
                     /translation="MCMGSSPSVPATPEVQAAPQEQDAAVVDARDEETRRRRAAAGRS
                     STLLTGSQGDTSTANTSGKTLLGQ"
     gene            36160..36236
                     /locus_tag="ROH59_001291"
     tRNA            36160..36236
                     /locus_tag="ROH59_001291"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36194..36196,aa:Arg,seq:tct)
     gene            36435..36857
                     /locus_tag="ROH59_001292"
     CDS             36435..36857
                     /locus_tag="ROH59_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803804.1"
                     /translation="MKTADMLAKYLNEWPCKYVRIVQGDDSIFYGVFAGNEMLCEAIP
                     GERLAGLTLSDDHGIGVTCHDWISAQKTEMEKGNVFDISRAVYAKEKSDDDYMRENLY
                     NMKLQCLAEVLSKRSLLDVVGAEQDAKAINAAFDKITF"
     gene            complement(36901..38376)
                     /locus_tag="ROH59_001293"
     CDS             complement(36901..38376)
                     /locus_tag="ROH59_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDX4803805.1"
                     /translation="MTDTALSPEEQLIEDIAGFTHDPLGYALYAFPWGEDGTELAHAT
                     GPRQWQADAFREIRDHLQNPETRYQPLMLARASGHGIGKSAFISMLINWGMSTCEDCK
                     VVVTANTDNQLRTKTWPEIIKWSNLAITKDWFTCTATAMYSNDPGHDKRWRADAIPWS
                     EHNTEAFAGLHNERKRIIVVFDEASNIADLVWEVAEGALTDEDTEIIWVAFGNPTRNT
                     GRFRECFRKYKHRWKTAQIDSRTVEGTNKQQLQKWVDDYGEDSDFVKIRVRGIFPDAS
                     ELQFIPTGLTDEAMKRVVTAAQVAHAPVIIGVDPAYSGVDDAVIYLRQGLHSKVLWTG
                     NKTTDDLIMAKRIADFEDQYQADAVFIDFGYGTGLKSIGDGWGRTWQLVPFGGASTDP
                     QMLNKRGEMFNSCKTWLRLGGMLDDQETADDLSAAEYKVRVDGKIVIEPKEDIKERLG
                     RSPGKGDALLLTFAFPVSKRLRIPGQQNQQGKAITDYDPFA"
     gene            complement(38373..39047)
                     /locus_tag="ROH59_001294"
     CDS             complement(38373..39047)
                     /locus_tag="ROH59_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDX4803806.1"
                     /translation="MNTAANYGGFILHGIITTTVTITTVVMMPAEPKTYKRKSTQFKP
                     LTAMQEAYCQSYIKTPENQTQAAINAGFSPNTAAVKASVMMRDERIQKRIAELMEERN
                     KRMRVSADYVLMRLVEIDQMDVIDILNDDGSLKPIREWPKIWRTTLSGFDLSSTIMNM
                     NEDSIETILKKIKWPDKVKNLELIGKHVDVNAFKERLDVNVNVTIADRIAAARKRLKE
                     RQDGNQ"
     gene            complement(39088..39426)
                     /locus_tag="ROH59_001295"
     CDS             complement(39088..39426)
                     /locus_tag="ROH59_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803807.1"
                     /translation="MAKSAAERKAAQRARQAASGVRKLEIVLDAQEIEILERNCATRR
                     PGRAPYEFGEYIALLIRQDDARVHGRIKSISRTRCGKCGERVPVNSCPCNGDSQCWVT
                     KGWHETKLIV"
     gene            complement(39419..39700)
                     /locus_tag="ROH59_001296"
     CDS             complement(39419..39700)
                     /locus_tag="ROH59_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDX4803808.1"
                     /translation="MANLQLAVKGEYFDAMIRGEKTEEYRLCNDYWNKRLVNRKYYRL
                     IITKGYPKREDFSRRIDVPYNGYEIKTITHPHFGDKPVKVFAIKVNIDG"
     gene            complement(39693..40466)
                     /locus_tag="ROH59_001297"
     CDS             complement(39693..40466)
                     /locus_tag="ROH59_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="HDX4803809.1"
                     /translation="MSTFTDKELIKEIKERIGSLDVRDNIERRAYEIALASLEAEPVA
                     WMRDDADGREYNARNEFSGGGGGVPLYATPPVPVVPEEKPMPNPLSMYAVDAVAAIAE
                     VRGWNACRAAMLHGAEPASNHEELPLDYLQGQKDGLEWAAQLAEANHPQTGDWLYDDP
                     LELAKAIRKGPDMPEFDGPTPVTLDGWISCSERMPENIPGSCKEYLVFDGLNNKVHHD
                     YWVVPDGDSAPVASFWNHYGAHVTHWMPLPEPPKEVNRG"
     gene            complement(40468..40827)
                     /locus_tag="ROH59_001298"
     CDS             complement(40468..40827)
                     /locus_tag="ROH59_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803810.1"
                     /translation="MSEINYQEGHEKVGQAKPVAWRYRYVKKGVTDFQGKQWVGDWKY
                     VPTKEDCNDRPNYEIQALFTAPPASVTSEGLVKAVRFYEQVKRENPPVETGAWKDAVD
                     WVLKEACQAVNIGTKGD"
     gene            complement(40824..41000)
                     /locus_tag="ROH59_001299"
     CDS             complement(40824..41000)
                     /locus_tag="ROH59_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803811.1"
                     /translation="MADFGSTKYNASFEEWHELLMDYAELRGGSAADAEAWRDDYEAG
                     KTPVEAYCDEWGDE"
     gene            complement(40993..41175)
                     /locus_tag="ROH59_001300"
     CDS             complement(40993..41175)
                     /locus_tag="ROH59_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803812.1"
                     /translation="MRKFKIIIETGIAGGDFEDEFEVDDDATPDEIQDEAKDIFFNYC
                     NYSYHEIKDEEEEQNG"
     gene            complement(41157..41390)
                     /locus_tag="ROH59_001301"
     CDS             complement(41157..41390)
                     /locus_tag="ROH59_001301"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803813.1"
                     /translation="MESNIKGLVAAGHEMASELKAECGAVDMRSVAKLISDLATQLEV
                     QLVRANALAAENALAQNIRRPSERAVVKCENSK"
     gene            complement(41452..41796)
                     /locus_tag="ROH59_001302"
     CDS             complement(41452..41796)
                     /locus_tag="ROH59_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HDX4803814.1"
                     /translation="MRKQIQALGRLKTGQMNKTESVYCQHLELRKRAGEIAWYRFEGI
                     KLRLADNTFYTPDFAVMLATGEMELHEVKGFWTDDARVKTKVAADQYPFRIIGVTVKP
                     KKAGGGWKIEEF"
     gene            complement(41914..42690)
                     /locus_tag="ROH59_001303"
     CDS             complement(41914..42690)
                     /locus_tag="ROH59_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDX4803815.1"
                     /translation="MKSTPELLNEYDRLREHGVAVHEERRDSNGKKEQVARIFNELFV
                     QLQAAFPASVSTIREQNKLNEFRKQWMLAFLENGITTMEQVNAGMRHARASESPFWPS
                     PGQFIKWCKDSKMVLGVTIDDVMAEFHRYSKEKSLYPGGPERFPWRHPVMYWVVCDTR
                     RAMYQRQLSEIEVEKHARRLLDDWAKKVASGQQIPDPVISIQAKPEPMSTPPDTGRDV
                     YHPPGRSFGCMPNAATLGGITPAQWLMEEYRRGKAAGFIK"
     gene            complement(42662..43492)
                     /locus_tag="ROH59_001304"
     CDS             complement(42662..43492)
                     /locus_tag="ROH59_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803816.1"
                     /translation="MASSWIKVEVITPDKPEIFQIAEILGIDPDAVLGKLVRIWAWAD
                     QQTIDGNAGSVTKGVLDRLAFITGFADALISVGWLAYHDGKLILPNFERHNGESSKKR
                     ALTNRRVAEHRKRVTQKVTPTALQKELPEEEEEEDIYKTPHIAHVREGAPTSEANGMP
                     LQVAEPEFLDGLSEPIGKFPMTDGWHPSPDFRRRAALWGTALPEPEFTPAELAAFRDY
                     WMAEGKVFTQVQWEQKFARHVNHIRGKSKNAGKSDELDWNNTDWIEGVWDEINSRTSQ
                     "
     gene            complement(43834..44064)
                     /locus_tag="ROH59_001305"
     CDS             complement(43834..44064)
                     /locus_tag="ROH59_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803817.1"
                     /translation="MSDNGHFDFKKHWLALTPDEREAFAQEAGTTSHYIQTHLTGKRK
                     MPGKVLMNGLFKACKTRQWLRSKAELAYFFYS"
     gene            44219..44803
                     /locus_tag="ROH59_001306"
     CDS             44219..44803
                     /locus_tag="ROH59_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4803818.1"
                     /translation="MKSIQDVRRQNLNDLIDREFNGVQTRMAEKLGTQANLVNRWALG
                     KKVIGDQVARKIEAAANKPRNWLDIDRSLSQEGFQPVGPSDIGQLAAHNLERWMSESR
                     DLSTQGKLHRASGVAQVTISRLLNNEVSVSISTLENVASAFGRHGYELLIHPHDPATI
                     NYDRSRYALLPETEKAKIESYIEFVINQNEKNKQ"
     gene            44957..45109
                     /locus_tag="ROH59_001307"
     CDS             44957..45109
                     /locus_tag="ROH59_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803819.1"
                     /translation="MQWKIINGWYCVTACGFMSWKFRTLQEGIKWAFVSKEARDVAND
                     NEIWEG"
     gene            45112..45411
                     /locus_tag="ROH59_001308"
     CDS             45112..45411
                     /locus_tag="ROH59_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005028273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803820.1"
                     /translation="MNVNQQKNLQKIMLAFDKDYRLSEQLYDRQVELIESIRLHQLAS
                     TFDAVTGKGVRQEVLEAAKDSPEFEELMDSYRREAMAIIARWDLADQLDGQRDAA"
     gene            45408..46229
                     /locus_tag="ROH59_001309"
     CDS             45408..46229
                     /locus_tag="ROH59_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HDX4803821.1"
                     /translation="MKPGIYFDISNEDYHAGDGVSKSQLDMVAKNPALLKWVQAAPED
                     EEKKSALDMGTALHCLLLEPGEFDKRFIVSPKFERRTKQGKADEEAFLRDIADMGISV
                     LDAEQWRKLELMRDSAMAHPAARWMLEAPGYCEASMYWNDEETGELCRIRPDKWLNEH
                     NVIVDVKKVADMDRFARHIEEFRYHVQDAMYREGAMRVTGQPHGFFFLAVSESIDCGR
                     YPVRVFELDAQDVDAGHALFRRDLNTYHECRINDEWGGVEIIKRPEWARKQDMYI"
     gene            46226..47167
                     /locus_tag="ROH59_001310"
     CDS             46226..47167
                     /locus_tag="ROH59_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001509282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HDX4803822.1"
                     /translation="MSNDIANINAPVDTAIAGTAATIFSPDGLNQLMKFAEVMAQSRV
                     TVPAHLAGKPADCMAVAMQAAQWGMNPFAVAQKTHVVNGTLGYEAQLVNAVISTMSPT
                     KDRINYEWFGPWERVIGKFVEKTSKNGNPYIAPGWTLKDEEGCGVRVWATMKGEDQPR
                     VLELMLSQAQVRNSTLWASDPKQQLAYLATKRWSRLHCPDVIMGVYTPDELQETAPRV
                     ERDITPQTTTAAGMNSLINAKPVKKPDEQTRKADSRDPEEMLMAFTSAAMNYSTVSEL
                     DKAYKYIEQKLSDDDELLAKATDVYSVRREELNETSM"
     gene            47217..47465
                     /locus_tag="ROH59_001311"
     CDS             47217..47465
                     /locus_tag="ROH59_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009485476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HDX4803823.1"
                     /translation="MKGALGKKELLAVVPLSWSTIDRMERAGEFPKRWYITDKRCAWN
                     RDEVERWLDERQAASPAEFQGKKPPVQQRVYRPVSNAA"
     gene            47623..47874
                     /locus_tag="ROH59_001312"
     CDS             47623..47874
                     /locus_tag="ROH59_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001429704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HDX4803824.1"
                     /translation="MRRPSKVIAVTPAAIEFEKRAIEREKKGQFRIAAHLWLQCMDVA
                     SGDVERARIAVRRDQCITKGNGLRRGDYSGIGCCGVVYD"
     gene            47867..48517
                     /locus_tag="ROH59_001313"
     CDS             47867..48517
                     /locus_tag="ROH59_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine methylase"
                     /protein_id="HDX4803825.1"
                     /translation="MTKKYTLIYADPPWVYRDKAADGNRGAGFKYPVMSVLDICRLPV
                     WDLAAENCLLAMWWVPTQPLEALKVVEAWGFRLMTMKGFTWIKCGSRQPDKLVMGMGH
                     MTRANSEDCLFAVKGKLPPRINAGIVQSFTAPRLEHSRKPDVVREKLVQLLGDVSRIE
                     LFARQSSHGFDVWGNQCEDSAVQLHPGYALDIGGLTNAFSNSPLSPTDNQGRERAA"
     gene            48514..48708
                     /locus_tag="ROH59_001314"
     CDS             48514..48708
                     /locus_tag="ROH59_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="HDX4803826.1"
                     /translation="MNMASPADLRKCLETANMLAHSGIRFVPIPAVTDAEFATLSAIF
                     ENKIESLAAEAEMEENQQNY"
     gene            complement(48712..49962)
                     /locus_tag="ROH59_001315"
     CDS             complement(48712..49962)
                     /locus_tag="ROH59_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX4803827.1"
                     /translation="MLTDTKLKNLKPQDKLYKVSDRDGLYVAVLTSGTVSFRYDYRIN
                     GRRETLVIGQYGRDGISLAEAREELIAAKKLLKAGQSPAAAKRDGIKKIRGAETFAVH
                     TDSYMKHVILADSTRAMKQVVIDRDILPVLGNKMMTEITTSMVRDLCDRIVERGGRAT
                     AVQAREIISSVYRHANDRGHGLFNPAADIKPSSIAIFKPRERTLTPEEIGLFFRTLDA
                     IGAMGTMKMALKLVLITMVRKGEFTNATWDEIDFKKWTWTIPSDRMKGSRAHVIYLPK
                     QAQDILVGLQMCAGGSEYLVPGRYNFRKPLSNAALNSLIDRTVKIINEDGEHIQGFTV
                     HDMRRTASTLLHEAGYPSDWIEKALAHEQKGVRAVYNKAEYARQRAYMLQQWADMIDS
                     WINGEHTDLIPFSPSKFEKWMAGE"
     gene            complement(50155..51732)
                     /gene="guaA"
                     /locus_tag="ROH59_001316"
     CDS             complement(50155..51732)
                     /gene="guaA"
                     /locus_tag="ROH59_001316"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDX4803828.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(51801..53267)
                     /gene="guaB"
                     /locus_tag="ROH59_001317"
     CDS             complement(51801..53267)
                     /gene="guaB"
                     /locus_tag="ROH59_001317"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDX4803829.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLSQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            53429..54796
                     /gene="xseA"
                     /locus_tag="ROH59_001318"
     CDS             53429..54796
                     /gene="xseA"
                     /locus_tag="ROH59_001318"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDX4803830.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFHPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKAKLQAEGLFDLQYKKSLPSPAHCVGVITSKTGATLHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANKRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPIVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     ARQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRAGQQQQRLTRQLVHQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTSAADGAVLKQVKQVKVGDTLTTRLGDGVVVSEVSAVTKTRK
                     PRKKT"
     gene            complement(54850..62931)
                     /locus_tag="ROH59_001319"
     CDS             complement(54850..62931)
                     /locus_tag="ROH59_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RatA-like protein"
                     /protein_id="HDX4803831.1"
                     /translation="MSVCLKPGKIIVLLGMLAAFMLSDFARAEVEWQTYPGSTGEFNG
                     TVPIADSASVPVYQGSVQLDPAASHDVAFSAKPNEFSVDDDAANLIVANPQDSEGDQF
                     STPPALRWENQTPPTVSLVWADAATPDTPLNPQPIANRSFCAQGLAGRSLVAWPQIDA
                     QQTIPLLYLLTSTGYPYEGTVVLADQKVTLNIAPAQGDLISVSASGYNETLGAAKTTV
                     GGTITLTVTTKDCQGNVAGNIPFIIKRKDAQNRQGAVNNTAPVVLDSTELTTTVTEYR
                     GTSDANGTATITVTQPNGPGVKTPLVVGISGIAQTSEAAVIFTVLTSPDVAQATMWGH
                     MAETVEAHGYTFSRPKLAAEVSNENATVVDHNETWSTFTWSGADSHCTVLPGMRHFGA
                     LATVIPSTVQTVLGWPMQGDYYWSSLAGLTGQHHAADVSNRGETQKPDSTTFLVSCVD
                     KPAPDVEPKIVLTPENYDDTAQAMKAKVGEDATMRLAITDTKNNDQPLAYYYFSLHLD
                     DGVNRKNQTDTAWEAHPVQIAGGSNFRQVDAHTYEGMTDANGQASLTLSQPGGAGVKT
                     HITARMRSDFNATDAKDVIFTVITSPDSDKARMWGHMRGIIESGSLYKRPLLADETEH
                     ELGTVRENNEDWALYDQNTSMQAECGVGHIPRQSSLESLFSAHPGNAIGTEYGWPTAQ
                     QGYLSAVEQATHSSVDLGNGSVDSYSGFKPNYLSCSGNEMVANVEVSTDHDVSVGTQA
                     QAKVGDTIVMTVRTINSLNNIPVPFTAFTITKGMGYNRAGQVSGFDDPSSGAITMDNT
                     QYGTSQSSKVYAGITDARGVATVEIKQPQGVGLKTVLSVTPVNSYLPNTVNYSVIFTT
                     PTSPDVTGAQMWGHMDETITVDSSTFTRPKLASEVASPDGTLTENNEIWARVSQANTS
                     STSKGGCDTNMLPRRSQLSALYNANSGNAVQTAHGWPTQRQPYWSNSPADKTPHFFTI
                     ALNDGAQTIGGDTPVYVSCLKTANKPASSITLEVVDKAQWNTGNSAATLKKGETLQVK
                     VTVKDAQGNALADMPFTLNRGDGYTRSGEKHVAGSGDALVAPVVVNGGLADETTLNDT
                     ATVYTAMTDNDGSKILNITRPDTHGTKTALTAMLYSDATKKSSIDTIFTVVTSPDSRL
                     AKMWGHMPETVTAADGTVFKRPLLLKELAYQTGRTSTSEDNENWALFNINYASFSTTY
                     SGCGTNYIPTQAGLTSLFANNAGNTMKTVQGWPVATRYLSNTSDNGSMEQRNYKAVDL
                     SNGTSAAVSSTTLELLTCQTAPIAAVSQILLEAADPVTLDTTYNVVKAKKSEESVVRV
                     ITKDAQGNLVGNTAFILTRANSVSRANSSATMSVGALTVTDAWGNTRNNFQSTSETIY
                     GVTGADGSTTFTLKQDNSTGLRTDLTAKLDTSSSVKAMLPVVFTVVTSPDSPKANFWG
                     HMAETVTASDGSVYKRPLLFGELTNNYARYSTFENGESWARFTSTQSADTSMNGCGTD
                     YMPTLDGLKSLYDANRGNAMNTVQGWPVNMSYLTNTPSNTQTGSRYYNVVQLNSGAVS
                     QIVSTVLALQTCRTTPLMTASQITLEASDPGQFVSIDSTLSAVKAKKGDEVSIRISTK
                     DAQGNLVGNTPFALKHANSINRQNVTSSQKVSVTTAAGATVDTSATTILYGVTGPDGT
                     TTMTLRQDASTGLRTDFYALLNDTGVSSDTLSVIFTVTTSPDTPLATNWGHMAETFTS
                     SEGVTFKRPFLKAELSGGTAKTANNEVWSLLTATEKADVSKAGCDEAYQPLTTDMQGL
                     YVDYPNGQLATVLGLPTAAGNWWDYDMMAVAGGSWSNQAFVPGNGQLIQASSSYTAIV
                     MCLVEPHTEAVTIELTSTAQDAAKSLSNDGRPSAVAKKGELIPLTVTVRDSAGNPMPY
                     ADFTLSRETTLDRAKATVNTSADDLTVTALVPVSRDSVLTASGAKTLATTGSDGTATF
                     EVGQYSTTGLATPLTVTLARDTTKVATLDVIYTVITSPDSPSAKFWGHMPDTFTSSAG
                     VTFKRPLLKTETSSGLSISSNGEVWSYMSNLQNLTSTDCPLENQPRSKELLDLYSDHP
                     NGAIMTDLGLPMNAGNWWAYDMAILGTTTWSYQTVSLRTGAIAKNSATNALMLCLAQP
                     HPAGVSVTLTSSALDDARTLSNGGRPSASVKKDNPLPIVVMVKDRDGNPLAGEAITLR
                     RDNAMSRSGTIVNTAANVMVLTELAPVSATFTLASHGTQWLGFTGSDGTAIFNVEQPD
                     TVGLATPFTAILARDTETTTVLDAIFTVVTSPDSAMAAYWGHMPDTVTAENGVVFERP
                     KLWKELPSTSGVSKVNSNNEVWPVFNATQRADSNLSPCEAARRPLSDDLESLYARYPG
                     NTLTTQIGWSTQYTWWALDNWLGGSNPQVVGLNNGSAWGTVNTAYQGCLVNPRATVSS
                     VTLTSTALDSSTQAAKVKKGDAVPVVVTVKDSVGKPVPNISFILKRGDATPRNSGATL
                     YGDVDTMDDLTVQPSSGAAVTLADSGNTIDGVTGADGTASFTVGQDNTPGYKTPLTVT
                     LTDNATITATLDTIFTVPTSPNVATAYFWGHMADTATVSGKMLHRPLLKSELPSGVTA
                     AATPNVNNETWALAHVIDSTKWDVARQCGSMNNVPSSAELQTLHSGFSTLGWPSSISF
                     PYLSTDKAGSFYCGVEEGSGSLNCGIQPAKTPGFATCFQ"
     gene            complement(63041..64033)
                     /locus_tag="ROH59_001320"
     CDS             complement(63041..64033)
                     /locus_tag="ROH59_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803832.1"
                     /translation="MKPHMKRGLTKVALALMLAGYCAVPVAMAEDAAWVASGTTAEFE
                     GTIPWLYREGGNATINSEDADHIKVTSDSKGIRPAGSESDKRLYSGDTITLGWDIGDT
                     EGDIDDGSAGIDAKTTATIKWYSYSDNAGGGKTELTAAAGKTSYKITDGDRGRYIGVE
                     IQPITQTGNPFQGTSLTLLDISTASGGGSDTDNVDPGPVVNQNLKVAIFEKDTSTNLI
                     GGNTAIALNKTYVAKLYSDENQNGKYDAGTDVDVTANYDFAWVFNGNSKQLAAAGGIA
                     NASFDNNDIVIPQTNEQARTSLNGSDRNGKTGLAIPANGDGVQGYTLSIIYKHH"
     gene            complement(64089..66263)
                     /gene="sinH"
                     /locus_tag="ROH59_001321"
     CDS             complement(64089..66263)
                     /gene="sinH"
                     /locus_tag="ROH59_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001385430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like inverse autotransporter SinH"
                     /protein_id="HDX4803833.1"
                     /translation="MLRWKRCIMLTFISGAAFAAPEINVKQNESLPDLGSQAAQQDEQ
                     TNKGKSLKERGADYVINSATQGFENLTPEALESQARSYLQSQITSTAQSYIEDTLSPY
                     GKVRSNLSIGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHN
                     FDKWLLGGNIFYDYDFTRGHRRLGIGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEE
                     RPASGWDIRAEAWLPAYPQLGGKIVFEHYYGDEVALFGTDNLEKDPFAVTLGVKYQPV
                     PLIAVGTDFKAGTGDNTDTTVNATLNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVER
                     NNFIVLEYKEKDPLDVTLWLKADAMNEHPECVIKDTPEEAIGLEKCKWTINALVNHHY
                     KIVAASWQAKNNAARTLVMPVIKENTLTEGNNNHWNLVLPVWQYSSDKAEQGKLNTWR
                     VRLALKDEKGNRQNSGVVEITVQQDRKIELIVNNIANVPEENNHSHEASAQADGVDGV
                     VMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTNNPCTTETPCVFIAKQD
                     KEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGADIGGLNAFIYRVGAAKSVNL
                     IGNKEPLPLNSRYRFVLWRDANKDGVFQLSEKLTDEEMKQYDYQWEFTGHSVNGNTGA
                     QANTTNVDIEIPATNKEAAAKFSAQVTDGVQGYGLQVNYSKT"
BASE COUNT        16293 a        17252 c        15606 g        17155 t
ORIGIN      
        1 atttcgtacc aaagattttg tcaccggcat cgccgaggcc cggaataatg tatccgtgct
       61 cgttcagtcc ctggtcaatc gatgcagtat acagttcgac gtccgggtgc gctttttcca
      121 gcgcagcgat accttctggt gcagctacca gcaccagaac tttgatgctg ctgcagcccg
      181 cttttttcag caggtcgatg gtcgcgataa cggaaccacc ggttgccagc attgggtcaa
      241 cgatcagcgc catacgctca tcgatgttag aaaccagttt ctggaagtac ggtaccggct
      301 ccagcgtttc ttcattacgg tacataccga cgacgctgat gcgcgcgctc ggaacgtttt
      361 ccagcacacc gtccatcatc cccagacccg cacgcagaat tggcacaacg gtaattttct
      421 tacctttgat ctggtcgatt tctaccgggc cgttccagcc ttcgatagtt actttttccg
      481 tttcgaggtc ggcggtcgct tcgtaagtca gcaggctacc cacttcggaa gcgagttcgc
      541 gaaagcgctt ggtgctgata tcttgctcac gcatcagtcc cagcttgtgt ttgacgagtg
      601 ggtgtttgac ttccacgatc ttcatactct ttctcctttg aggggcagcc acaaaaaaaa
      661 tcgacggatt atacctcctt tcttcaaggc ggcaatatta ttttcgttga ctttagtcaa
      721 aatgataacg gtttgagata aagttatttt atattcaaat agttatgaaa gaagattatt
      781 ccatccgaaa acgatccttt gccctggtac aagtattctt tcgccgcgcg cctggggaaa
      841 agacgtgcaa aaaggttgtg taaagcagtc tcgcaaacgt ttgctttccc tgttagaatt
      901 gcgccgaatt ttatttttct accgcaagta acgcgtgggg acccaagcag tgaccgataa
      961 aacctctctt agctacaaag atgccggtgt tgatattgac gcgggtaatg ctctggttgg
     1021 aagaatcaaa ggcgtagtga agaaaacgcg tcgtccggaa gtgatgggcg gtctgggcgg
     1081 cttcggtgcg ctgtgtgcat tgccgcaaaa atatcgtgaa cctgtgctgg tttccggcac
     1141 tgacggcgta ggtaccaagc tgcgtctggc gatggactta aaacgtcacg acaccattgg
     1201 tattgatctg gtcgccatgt gcgttaatga cctggtggtg caaggtgcgg aaccgctgtt
     1261 tttcctcgac tattacgcaa ccggaaaact ggatgttgat accgcttcag cggtgatcag
     1321 cggcattgcg gaaggttgtc tgcaatcggg ctgttcactg gtgggtggcg aaacggcgga
     1381 aatgccgggg atgtatcacg gtgaagatta cgatgtcgct ggtttctgcg ttggcgtggt
     1441 agaaaaatca gaaatcatcg acggatctaa agtcagcgac ggcgatgtgc tgattgcact
     1501 cggctccagc ggcccgcact cgaacggcta ttcgctggtg cgcaaaattc ttgaagtcag
     1561 cggttgtgat ccgcaaacca ccgaacttga tggtaagcca ttagccgatc atctgctggc
     1621 accgacccgc atttacgtga agtcagtgct gaaattgatt gaaaaggtcg atgtgcatgc
     1681 cattgcgcac ctgaccggcg gcggcttctg ggaaaacatt ccgcgcgtat tgccagataa
     1741 tacccaggca gtgattgatg aatcttcctg gcagtggccg gaagtgttca actggctgca
     1801 aacggcaggt aacgttgagc gccatgaaat gtatcgcacc ttcaactgcg gcgtcggtat
     1861 gattattgcc ctgcctgctc cggaagtgga caaagccctc gccctgctca atgccaacgg
     1921 tgaaaacgcg tggaaaatcg gtatcatcaa agcctctgat tccgaacaac gcgtggttat
     1981 cgaataatga atattgtggt gcttatttcc ggcaacggaa gtaatttgca ggcaattatt
     2041 gacgcctgca aaaccaacaa aattaaaggc accgtacggg cagttttcag caataaggcc
     2101 gacgcgttcg gccttgaacg cgcccgccag gcgggtattg caacgcatac gctcatcacc
     2161 agcgcgtttg acagtcgtga agcctatgac cgggagttga ttcatgaaat cgacatgtac
     2221 gcacccgatg tggtcgtgct ggctggtttt atgcgcattc tcagcccggc gtttgtctcc
     2281 cactatgctg ggcgtttgct gaacattcac ccttctctgc tgccgaaata tcccggatta
     2341 cacacccatc gtcaggcgct ggaaaatggc gatgaagagc acggtacatc ggtgcatttc
     2401 gtcaccgatg aactggacgg tggcccggtt attttacagg cgaaagtccc ggtatttgct
     2461 ggtgatacgg aagatgacat caccgcccgc gtgcaaaccc aggaacacgc tatttatcca
     2521 ctggtgatta gctggtttgc cgatggtcgt ctgaaaatgc acgaaaacgc cgcgtggctg
     2581 gatggtcaac gtctgccgcc gcagggctac gctgccgacg agtaatgccc ccgtagttaa
     2641 agcgccagct ctgccgctgg cgtttttcaa ttcacctgta aatcgcaagc tccagcagtt
     2701 tttttccccc ttttctggca tagttggaca tctgccaata ttgctcgcca taatatccag
     2761 gcagtgtccc gtgaataaaa cggagtaaaa gtggtaatgg gtcaggaaaa gctatacatc
     2821 gaaaaagagc tcagttggtt atcgttcaat gaacgcgtgc ttcaggaagc ggcggacaaa
     2881 tctaacccgc tgattgaaag gatgcgtttc ctggggatct attccaataa ccttgatgag
     2941 ttctataaag tccgcttcgc tgaactgaag cgacgcatca ttattagcga agaacaaggt
     3001 tccaactctc attcccgcca tttactgggc aaaattcagt cccgggtgct gaaagccgat
     3061 caggaattcg acggcctcta caacgagttg ttgctagaga tggcgcgcaa ccagatcttc
     3121 ctgattaatg aacgccagct ctccgtcaat caacaaaact ggctgcgtca ttattttaag
     3181 cagtatctgc gtcagcacat tacgccgatt ttaatcaatc ctgacactga tttagtgcag
     3241 ttcctgaaag atgattacac ctatctggcg gtggaaatta tccgtggcga taccatccgt
     3301 tacgcgctgc tggagatccc atcagataaa gtgccgcgct ttgtgaattt accgccagaa
     3361 gcgccgcgtc gacgcaagcc gatgattctt ctggataaca ttctgcgtta ctgccttgat
     3421 gatattttca aaggcttctt tgattatgac gcgctgaatg cctattcaat gaagatgacc
     3481 cgcgatgccg aatacgattt agtgcatgag atggaagcca gcctgatgga gttgatgtct
     3541 tccagtctca agcagcgttt aactgctgag ccggtgcgtt ttgtttatca gcgcgatatg
     3601 cccaatgcgc tggttgaagt gttacgcgaa aaactgacta tttcccgcta cgactccatc
     3661 gtccccggcg gtcgttatca taattttaaa gactttatta atttccccaa tgtcggcaaa
     3721 gccaatctgg tgaacaaacc actgccacgt ttacgccaca tttggtttga taaagcccag
     3781 ttccgcaacg gttttgatgc cattcgtgag cgcgatgtgc tgctctatta tccttatcat
     3841 acctttgagc atgtactgga actgctgcgt caggcttcgt tcgacccgag cgtactggcg
     3901 attaaaatta acatttaccg cgtggcgaaa gattcacgca tcatcgactc gatgatccac
     3961 gccgcacaca acggtaagaa agtcaccgtg gtggttgagt tacaggcacg tttcgacgaa
     4021 gaagccaaca ttcactgggc gaagcgcctg accgaagcag gcgtgcacgt tatcttctct
     4081 gcgccggggc tgaaaattca cgccaaactg ttcctgattt cacgtaaaga aaacggtgaa
     4141 gtggtgcgtt acgcacacat cgggaccggg aactttaacg aaaaaaccgc gcgtctttat
     4201 actgactatt cgttgctgac cgccgatgcg cgcatcacta acgaagtacg gcgggtgttc
     4261 aactttattg aaaacccata ccgtccggtg acatttgatt atttaatggt gtcgccgcaa
     4321 aactctcgcc gtctgttgta tgaaatggtg gaccgcgaga tcgccaacgc gcagcaaggg
     4381 ctgcccagtg gtatcaccct gaagctaaat aaccttgtcg ataaaggtct ggttgatcgt
     4441 ctgtatgcgg cctccagctc cggcgtaccg gttaatctgc tggtgcgcgg aatgtgttct
     4501 ctgatcccca atctggaagg cattagcgac aacattcgtg ccatcagtat tgttgaccgt
     4561 taccttgaac atgaccgggt ttatattttt gaaaatggcg gcgataaaaa ggtctacctt
     4621 tcttccgccg actggatgac gcgcaatatt gattatcgta ttgaagtggc aacgccgctg
     4681 ctcgatccgc gcctgaagca gcgggtgctg gacatcatcg acatattgtt cagcgatacg
     4741 gtcaaagcac gttatatcga taaagaactc agtaatcgct acgttccccg cggcaatcgc
     4801 cgcaaagtac gggcgcagtt ggcgatttac gactacatca aatcactcga acaatctgaa
     4861 taaccctatg ccaatacacg ataaatcccc tcgtccgcag gagtttgctg cggtcgatct
     4921 tggttcaaac agttttcaca tggtcatagc ccgtgtggta gatggtgcca tgcagattat
     4981 tggccgcctg aaacagcggg tgcatctggc ggacggcctg gggccagata atatgttgag
     5041 tgaagaggca atgacgcgcg gtttgaactg tctgtcgcta tttgccgaaa ggctacaagg
     5101 gttttcccct gccagcgtct gtatagttgg tacccatacg ctgcgtcagg cgctgaacgc
     5161 cactgacttt ctgaaacgcg cggaaaaagt cattccctac ccgatcgaaa ttatttccgg
     5221 taatgaagaa gcccgtctga tttttatggg cgtggaacat acccaaccgg aaaaaggtcg
     5281 caaactggtt attgatattg gcggcggttc tacagaactg gtgattggtg aaaatttcga
     5341 accgattctc gttgaaagcc gccggatggg ttgtgtcagc tttgcccagc tttatttccc
     5401 tggcggggtc atcaataaag agaattttca gcgcgctcgc atggcggcag cacaaaaact
     5461 ggaaacgtta acctggcaat ttcgaattca gggctggaac gtggcaatgg gcgcttccgg
     5521 taccataaaa gccgcccatg aagtgttaat ggaaatgggc gagaaagacg ggataattac
     5581 cccggaacgt ctggaaaaac tggtaaaaga agttttacgt caccgtaatt tcgcatcgct
     5641 gagtttaccg ggtctttccg aagaacggaa aacagtcttc gttccgggac tggcgatttt
     5701 atgcggtgtg tttgatgctt tagccatccg tgaactgcgc ctttctgacg gggcgttacg
     5761 cgaaggcgta ctgtatgaaa tggaaggacg tttccgtcat caggatgtgc gtagtcgcac
     5821 tgccagcagc ctcgccaacc agtatcacat cgacagcgaa caggcccgac gggtgctgga
     5881 taccactatg caaatgtacg aacagtggcg ggaacagcaa ccgaagctgg cgcatccaca
     5941 actggaggcg ctactgcgat gggccgccat gctgcatgag gtcgggttga atatcaacca
     6001 cagcggtttg catcgccact ccgcttatat tctgcaaaac agcgacttgc cgggttttaa
     6061 tcaggaacag cagctgatga tggcgacact ggtgcgctat caccgtaaag cgattaaact
     6121 cgacgatctg ccgcgcttta ccttgtttaa gaagaaacag ttcctgccac tgattcagct
     6181 attgcgcctt ggcgtattac tcaataatca acgtcaggca accaccacac cgccaacatt
     6241 gacgctgatt actgatgaca gtcactggac actgcgtttc ccgcatgact ggtttagtca
     6301 gaatgcgctg gtactgcttg atctggaaaa ggagcaagaa tactgggaag gcgtggctgg
     6361 ctggcggttg aaaattgaag aagaaagtac accagaaatc gccgcttaat gctttgcggg
     6421 ccgacgagaa atgtcggccc gcattattca ggcactttcg cgaatgggtt cgatttcatt
     6481 cagcgtatca attaacggtt gcggcttacc aataagataa ccctgcatat aatcgatccc
     6541 caaagagagc accgcctcgc ggatctcttc gttttcaacg tactctgcca ctacccgcat
     6601 tttcttcatt cgcgccaggt ggcaaatcga cgccactatc tgataatcca gactatttga
     6661 cacaatattg cggataaaac tgccgtcaat tttaagcaga tcggcattca catttttaag
     6721 ccgcgcatag ctggcgtagc cggtgccgaa atcatcaatc gcaatctggc agcctaattc
     6781 ctgaagatgc tgcaaggtga tttgcgcctg cttaacattg gtcagagcat tactttcggt
     6841 gacttcaaaa ataagttgcc acgcttcaat ctgatattta gccagcagct gactgacttc
     6901 aacaggaaaa cgagcctgac ataccgaggt tggagacaga ttaatagcaa aacggtgagc
     6961 gggcatcttc gctctgtttt cagccataaa ttgcagcgta tgctcaatga cccacatgtc
     7021 gatactcgac gataaaccaa attcgtgcgc gaccggtaag aagctatcgg ggctgatcag
     7081 ctcatcattc tcacccttca tgcgcagaag aatttcatgg taaacatcac cacgcatacc
     7141 ggtaatcggc tgggccatca ggaaaaaatg gttgtgttcc agcgcctgct gtagtcgatt
     7201 catcatcgcg actttatctt tcaattcgcg ttgcaaatac attgctccgc gacgctgcat
     7261 attttccggg acgttggtca cgatggaaag ttcggccacc gtatttagct ctcccagcag
     7321 caggtagata tgattcactg gcgagcgcac atagcagtaa ctgacgccaa tctgcggttg
     7381 catcggcatt ccatcccaaa agaaacgaaa ttgcttgaga tggctatcca gtgcggtaat
     7441 gcgctcctgg tgcgattctg tattcagccg cagcgcgaga tcgttacccg aaagctgata
     7501 aacatcttca cccggttcca gcaatggtga cagccagtga gaaagttttt gcttgtattg
     7561 aatccgcagc atgatgccat agttcttaac cagcatttcc atgccaggga tgtgtaaata
     7621 gcatagcgca gaccaggggg catcacgcaa cgcgcgattc agggcgcgaa catttggcag
     7681 atgaaccacc gggtccacat acgcaagccg ctgaatgcgt ctgactacag ctcgctgacg
     7741 ggttgccagt acagccatat aattgacaat aaaagagaat accagataac tggaggaggt
     7801 tatggtcagc tgcgtggtat agccaggata aatgggaatg taattttgat agctatggat
     7861 gctgatcatc aacacgaccg cccagagcaa tgaaatcaac ttataaccat agcgcatcgc
     7921 tccccacatc atcaggggca gcaataatga caaggtgtaa ttggtgctaa aaatcgtgct
     7981 tttttcattt aacggcatgc ataacagcaa caataaggca cctaatgcca gtagccagat
     8041 tgcgaactct tttttggtaa ctttggcatc aacctgctgt tttaattgcg aataatagct
     8101 acgtaaataa aacggatttc gcaccacccg aatgataaag tagcacagcg ggacaccaat
     8161 cagattaccc accagcaagg cctgataatt gattaaggtc ccgaggttaa agggcatgac
     8221 gccgaccaga ttttctctgc tcgccagtaa ccctacaaac gcagcaaact ggaaaagtat
     8281 cagaaacagc gttgcaggaa acacaatctg ccagaatagt cgctgggaaa ttaaacggct
     8341 atcaccatgt gaaacgttgt tacgccgggg ggtaaaaacc ctgtaaccgc cccaacagag
     8401 aatgataatg ataataaaat tagccgttaa tgagagcgtt tcgtaaaaac ccagctctgc
     8461 atatttgcgg acaaaaatcc ctaaggcgat ccctggcaat gccgcccagc tgaaaaacat
     8521 catcatgctg atcatcagtg ccagtggcag ataaaagaga aaaacttcac cggaagaaat
     8581 atgcgcgaaa gtattaatgt gggcgaaaat gggcaagatt aaagaaggca ggaacagcgg
     8641 aagcccccac catttatcac gtatttttat ataagttgca ttcagtttca tagatgctca
     8701 gcagaatccc ccacatcctg aaggaggtgt attcagacag gcatcccacc tgacttcgaa
     8761 tgatgattat tcatcactat agagagcaat gattctaagt gtcatatgaa agttccaatt
     8821 gatatatatc aaacaaaata accctgatta atgaattatt acgtttatca tgttaactca
     8881 tcattattac atcatcattg taaataatta aattaacttc cataacatta aaatatgtat
     8941 tcactgacgc ttctttacat aacgaagaat tgaccatttt gtcctgttgt gccttaatgt
     9001 aagtaccgtc cacggcgtgg gacatacttc aaggaacctt ttgtgagtca ggcaaccagt
     9061 atgcgaaaac gacaccgatt taacagtcgc atgacccgta tcgtactgct catcagcttt
     9121 atcttcttct ttggccgttt tatctactcg tccgtcggtg cctggcagca ccatcagagc
     9181 aaaaaagaag ctcagcaatc cacactctcc gtcgaatcac cggtacaacg ttagcggtta
     9241 ccttctccac tctcacagaa cataacggca cctcgctgtc ggatgctttt gctctttgag
     9301 attatcaaag cggcagatat tctttcatct taaattttac gtctttgttc tgactgcagt
     9361 tcggctgcga aataaataca tcattaatac atatgttgtg atgatgtatt tttataaatt
     9421 attccccaca tgaattttaa taaatttaat ctattccttt atacgcaata catttacttt
     9481 cctcttttga tgatcttaaa tgtcttattt ttcgtaatgt gtataacaag gaatagtgat
     9541 gaaatttaaa aaatgtcttc tgcctgtggc aatgttagcg tcattcactc tggcaggatg
     9601 ccagtcaaat gctgatgatc atgccgccga tgtttatcaa accgatcaac tgaataccaa
     9661 acaagaaact aaaaccgtta atattatttc cattcttccc gcaaaagttg ccgtagacaa
     9721 cgcccaaaat aaacggaacg cacaagcctt cggcgcgctt attggcgctg tcgctggcgg
     9781 tgttatcggc cacaacgtcg ggtctggcag caattccgga acgacggcag gtgcagttgg
     9841 cggcggagct gtaggcgcgg cagcgggttc tatggtgaat gataaaacct tagtggaagg
     9901 tgtttcttta acatataagg aaggcaccaa agtgtatacc tccacccaag tgggtaaaga
     9961 gtgccagttt acgacaggtt tagccgttgt tattaccacg acgtataacg aaacgcgtat
    10021 tcagccaaat accaaatgtc ctgaaaagag ctaataatca ggaggagtca tgaagaaagt
    10081 ttttctttgc gccatcttag cctccttaag ctatccggct atcgcctcat cattgcagga
    10141 tcaactctcg gctgtcgcag aagcggaaca gcaaggtaaa aatgaagagc aaaggcagca
    10201 tgacgaatgg gtcgcggagc gcaacaggga aatccagcaa gagaagcaac gtcgcgcaaa
    10261 cgcccaggcc gcggctaata aaagagcggc aacggcagca gcgaataaga aagctcgtca
    10321 ggataaactg gacgccgaag ccactgcgga caaaaaacgc gatcaaagtt atgaagatga
    10381 gctacgtagc ttagagattc agaaacaaaa actggcgctg gcgaaagaag aagcccgcgt
    10441 taagcgcgaa aacgaattta tcgatcagga actgaagcac aaagctgcgc aaaccgatgt
    10501 ggtgcaatct gaagctgacg caaacagaaa tatgactgaa ggcggtcgcg atctgatgaa
    10561 aagcgtgggt aaagcagaag agaataaatc agatagctgg tttaactaaa cgatgttagt
    10621 aacttcaaac ctataattct ttaggataaa aaaccctctg tagtaacaga gggttttgtt
    10681 cattcatagt gcagggtcaa atcattccca ctcaattatt tacgatacac ataaacaatt
    10741 gactgataac aactttcttc caaatgattt tcaccgtacc gttttatata ccgtcaccgg
    10801 aaatcagtgc cacgattttt gcttcttcag tgaatcgtat tgctgttcgc aggattctcc
    10861 tgcaatccga tacttttcag cctcagctgc tgttgcgttg taaactcggt tgctttcttc
    10921 aagcatgtcg gcgagcacac cgatgacctt gctggctggc gtgccagtgg ggaaagatcc
    10981 ggtatagtgt tcggcgagtc gcttggtttt gtcaagctcg gcgcgcaggc tgtcagcagc
    11041 ggcattagca tgctcagcat caacacgcgc cacatcgata cgggactgtg cttcacgttc
    11101 aatttgtgtt ttctcctgat cacgttgtga cctggcctta tcatcagcct gtttctgatc
    11161 ttcctgtgcc tgcgcatacc cggcgtcgta ctgacgactg ccgtgtgcat tccaggctac
    11221 aactcctgat atgaccagaa cagcaagcat cgccatgata accaactgtt tccagtatgc
    11281 ttttgcgaat gcccagatca taccgccagc accttactgg cagtgatgta ccgcgcgcgc
    11341 cggtcgtcga tgccgttccg gccaccattg ataatcagag ttacacgtgc aatatcgccg
    11401 gtatacttca tgcatccttt gctggcaaag aaccacgccg cgctacgagc cgcgtattcg
    11461 tcctgcgcca gcagttcagg actctccagc aggtcaacct taagaccgtt tccacagtca
    11521 cgatagttat tcaaaccggt aatctggata agtccgcgac cacggtaatt ccagccatca
    11581 ccagaggcat tgttacccat gcgtttgctg tacaccagat ttgcgatcgc gcgctggcgc
    11641 tcaagtggca atggtggctc accagcacgg cggcccagtg cgttagcctg tccctgggtg
    11701 agacgcccag cccgaacgaa gttagccagt ccggtgacgc tgtagttgaa attttcctgc
    11761 aaccggttga agccaccaga ctcatgcccg acctgagcaa taaacattgc ctgatcttcg
    11821 ggtttgctga taccaaactc tttcatcgca gaagttatat gcgagaacca gcgagcggcc
    11881 agcgcctcgc taataccagc agctcgctgg aattgtttaa tctccatgtt tagacctcga
    11941 tattttgaaa atatgaacaa cgttaccgcg tgttttaata accgcggcaa gcatgacagc
    12001 gttgataatg acctcagata aatccacagc cattggcgtg cgtaaccaga ttgcatagac
    12061 gacacgaaca ggaatacttg ccgcagcaac aataaggaaa taagcaagcc accctcccca
    12121 tcttcgatgt tgagagccgt tacgccggaa tgtgacaacg cgaattgcta tgccagtaca
    12181 aataactgca ttggtgataa gcaaaaaaaa ctcatgcgtt accatcgtct tttctccccg
    12241 gaattaactc gcgtggatta tcggaacggt gatagagcca gatgccaata cgcacggcga
    12301 caattgctga cacgaatgcg cctgcagaga aaacaatccc tttttcaaaa gagtcctgcg
    12361 tgatggtagg gatcaggctg gctatgccga taagaattga tgctgctggt ttgtaaaaga
    12421 gaaggccgca aagaaagctg agcatcgaca ggagcacccg gcgacggatg gggtactcta
    12481 ctgcagaggt aacaaaaatt accgccccag ccaaagcccc taaagcaacc tccggaggga
    12541 cacctgcaat aaccgcagca agagaactaa cactaagcca ctgatttgaa gtttcattgg
    12601 ttagttggaa tgacataacg aaacccgttt atttgcaaac accctgcttc aggaaaagta
    12661 taccgcgcaa caacacacca tttacggttc aattccctgt taattgcaaa acttgctctt
    12721 ccagcttttt aaccctgcgt ctcatcatcg cagattccag aatcagagcc tcttcataac
    12781 ggataccgta acattcacca gcctcgacgg cttcgcgtac cagaaccttt gtctgtataa
    12841 gtgggtaaac tcctgcagaa tgctcttctt ccgtcacatc cctgtattct gccggggtct
    12901 cattccactt gtcataacag ataaatgcca gtcgtgacac atctatgcct tcattctgaa
    12961 atacactgat aacatgctgc gcaactgcac caaagtgcca tcttgctccg tctttacctt
    13021 tcacttcgat cctgtcaagg tactggtatg aaacccattc cactctttcc catgcgtcca
    13081 gtattttctc atcaataacc tctggagcag tcttgaaacg cgcatcggac agcaccgtaa
    13141 acgctgactg ggtaaatccc cccgaccatg cacgaccagc caacccaaga gaataagtat
    13201 tcgttgtcga tggtgtcatg gctgaatcag aaaactgtat atattctgaa tttccagtag
    13261 atattcgaat atttccattt attagcgaca tagtgccttt agtattatca ctattgaata
    13321 atttcaattg cgaacttata ccgcctccca cagccagaga tacatcgcct tcagcaagca
    13381 ttctgaattt atctgcagaa acaagcgtct ggttagcaag gttaaaatat ttaacccacc
    13441 attcaaaacg ccctgacata gtcccaacgt actgaccaag cgcagggacg tgaacaacat
    13501 tgctatttgt agtgccgtct atactggaaa taccagtcac cgctgatgca gaactcagaa
    13561 tattatttct gtcacccgga tgtttaattt caacaaagtt cctgatacac ccttcctcga
    13621 aggtaaccac gccggaagaa ctatacatgg ggaatattga cgcataatta ctgcgtgcag
    13681 catctaagaa acgaatggtt gtagatgtct gcagatctcc tgattcattt ttcccatcac
    13741 acccagtcat tagaatatta ctggcaatat tattatttcc ctgaacggtg actccgtgcg
    13801 cctgctttgc gtccgattca gagtaatcaa ccagcacatt cgaaatcagg ttaccagtcc
    13861 ccttgccaac aactactgcg gcgtattttg ggttgttagc cattacactg ctaatgatat
    13921 tattcgttgg ggcagtttcc gtctcagttc cattgtaaac aacgtgctga cactcttcac
    13981 caataacatt gctgacaatg ttatattttg ctgctgtttt aagttccact gcaccaaact
    14041 gaggataatt tctggctatc acaccatcaa ttagcgtatt ttgcgatgaa tcaaaaagca
    14101 cacaacctgc ttttttatta tttgcgaacc ctaaatactc tcctcttata tctctaacaa
    14161 tgtaacctga cggaatacca ttattcggat aagcgatcaa gctaaatcct gttcctcgcg
    14221 tatttgtaaa tctgatattt ttaaccgata catcatggcc acctgaaaat gacacctggt
    14281 gtccctgcac actatcatct gatttatttc ccataattgt tagcgtacta agcatgccac
    14341 catcgggcat gttaaaaacc agatgattac catctctgtc atactgtttt atcgttcccc
    14401 cacctgttcc gtacaagcca caacgtgaaa gagaaactaa agatgtattg aatacccctt
    14461 ccggaacaaa aacactgcta aacgaatgta atgattttgt aaaagcctcc ttgttatcat
    14521 ttaagattcc attttgagct ccaaaatcct taatgctgac accatcacgc atcttatcct
    14581 ggagtgttct gtataccgct ccagaaccat actgaataaa ccaaccaaaa ccaccaacaa
    14641 ccccggcgat tgcagcatcg acataattac gcattgagcg attatttaca gcgtcctgct
    14701 caagtgatgg atcggcaagg ttagatattc tgttttgctt tgcatcgtaa tattttgcaa
    14761 gcaaagatgg tttcatcaat gcacgtctga accacccaaa acatcgctgg atcagcatcg
    14821 tcaggtagtc aaatgcatcc tcatgaactt cggggaaaaa ttttccctga ttgcgaagat
    14881 cagtctcctg caccacatca agcacacgct ctatcgtgat tcgccagcca gcagcaagcg
    14941 gcgacggaag aaccactgca ccgccactat aagttcccgc ccctgttacc gtataaccag
    15001 catccagcac tagttttgta acgttaccgt taaggtcaga cacctgaaca accaggtcgg
    15061 attttttgaa aatacggaag gtatacggaa atgatgtcgt aacgccgtta cctgtgtatt
    15121 cgttgtggtc aacttcggtt gagaccgtca tgttaaatct ccagatagtc gcagcacccg
    15181 ttgcgccgca tatctggtta ttctattacc cgaaaaacca tatatggata gagagactgt
    15241 gaatatgaat agatattacc tttcaggtaa ttttcaaaac gtgctggata gcaaacaaat
    15301 tatttgctac tgtataaata tacagttatt gcatggagaa gattaagatg cagcagtatc
    15361 actatccact ggaagaggga tttaccgaaa ggattcacac gccgggaggc gtcaggtcac
    15421 tggtggaggg atcgcacttg atgaaattac tccgggatct cgataaggat ggatttaatg
    15481 tcgatggtcc acttgccgaa ctgactgcac tgattaacta cgtcaccagc tcacagatgt
    15541 ctatgcggga tctgcaaaca catctcgact attgtgccga acaattacga aaacaaacca
    15601 gataaggttt gtaattacca agtggagtgc ttatatttac ctttgcggta aatttacacc
    15661 gcactcctct tgtgccatag taatcgggca ctggcaaaat ccagtgccgg gattggtctc
    15721 ccggattact aagtggcgca taccacgcca gacgtggttt ttttatgcgt atagcacagt
    15781 catgccagaa ttatggtggg ctgaatgggg gtccgaaagg acgccggtac cacttaggcc
    15841 ggtaagacca actccgttca gttcaccacc atctgattgg tctcagcggt ggtgatgtaa
    15901 ttcgctaagt ggagacgcca tcatgaacgc tcaactcatc cccgtattca acggcactat
    15961 cgccaacgaa accactcttc tcgttaatgc tcgcgattta catacttttc ttggggtagg
    16021 taaacgcttt gcatcgtgga ttacagaacg cattgctgaa tatggtttcg ttgaaaatca
    16081 ggactatatt ttggtttccc caaatcggga aatcaaaggt cgaggaggcg atcgccgtag
    16141 caaagactat cacctcaccc tcgatacggc caaagaaact gcgatggtcg agcgcaacga
    16201 aaaaggccgc cagatacgcc gatacttcat tgaatgcgag aaacgtttaa gacaacaaga
    16261 aacaaaggtg gagaaggtct tgtcaggctt catgcccgcc attatggagg cgatcaagct
    16321 ggaagacaaa aaagaataca gtgccccact gaagcccggc taccgcagtc tgattcactc
    16381 gccgtcgggt gttctcggcc tgacggagaa ctcactgctg atgaatctgc tgaaccagtt
    16441 acaggaagac gggcacgacg tatcgggcgc ggcggcggag ctgaccacca tgttctgcta
    16501 catcgtcggt gtgagcaaat gcctgcgtga tatccagacc cacgcggagt acatcaacga
    16561 caaggcaggg ttcttctgac ggcggcggca cagggacgtg caaaacgaaa ctatcgtgac
    16621 atgtcacagg ccgctttcgc ggccttgttt ttaacgaatg ccaccgccgc ctgggcggga
    16681 atccgcagaa cgcccaccgc agcgggagcc gtcagcggca gtatcgctgt cgtgctgaca
    16741 acgaccggca aaggcctgag ttgaagctac cagagacaac aaaacgaaca gtgcagcaaa
    16801 tgcttttttc attgtgaaat ttccatctat aagccacctc aatgtggcgt caatgagtgt
    16861 agcactgact tttgtttcgt ccacaaaaaa gcccgcgctg cgggcttcta ttaatgcagt
    16921 ttatctttgc ttataaccag tagtctgtgg gtatgcacat ctttatcact gccccaacag
    16981 aaatcagccc actggctata gaaatcatcc catgatgtca tgaagctaag aggtctatct
    17041 tcttcagagc catctgaaac gtatacatta tatcctgggg tgtttatagc ccaagaaatc
    17101 attctttccc agaatcttct cccatcgatt gtttgttgct catcagatac aacgatcgca
    17161 tattgctcta ggaagaactg aaaaaaaatc tgaggcaaac catgaacagc acggtcatga
    17221 ataacattag gcgtacgcca taccatgatc tgcgtacatg ttcttttggc ttcgacgata
    17281 tcttcccgaa agattaactt aaccgcatac accgtttctg gagtatcgct ggtagtaatc
    17341 attctgtaat gatcgccatt acaagatttt acaaggcgat aaccataagg tgttgtgaat
    17401 cccggaagaa cgaaatcaac cacacctttc gctaagtagc tttcggtgtg actagtgttc
    17461 ttctcagaca tgttcagttt tctatcgaaa tctgcttctg ggataatgta tggcatcgct
    17521 tttcttgttg tatttgttct catttcgtcc tcccatgttt ggctacagga cgcgttttga
    17581 agggaagatt aaaaatgctt tcttaccctt gaggtaatag tacgctattc acccccagtc
    17641 tgcaatctgt acagaattat ttaaaggcac atccctgtgc cgccgcccgt cagaagaacc
    17701 ctgccttgtc gttgatgtac tccgcgtgcg tctggatatc acgcaggcat ttgctcacac
    17761 cgacgatgta gcagaacatg gtggtcagtt ccgccgccgc gcccgatacg tcgtgcccgt
    17821 cttcctgtaa ctggttcagc agattcatca gcagtgagtt ctccgtcagg ccgagaacac
    17881 ccgacggcga atgaatcagg ctgcggtagc cgggcttcag cggggcactg taggttttgt
    17941 tctctatctt catcgcctgc attactgctg acgccgtggc gttggctacc tggtcggcaa
    18001 ccatctttat gcgttcttcc tgcgggagcg agtttttaat gtaacttccg gtgcggcgga
    18061 tctgaggaag aacctcacct gtaacccatt tacgaaagcg gtatgggata gtgcctggtg
    18121 tcaccgcatc gcggcagcgg aggatcagtg tgtagaggcc tgactcggag ataatgatcg
    18181 attcttgctc accgccaggg gtgtcggttg aagcgacgcc cttctcatca tcatcaagtt
    18241 ttcgaacagc atctcgatgg tttgctatgc ctatagcccg acaaacatct gaagcgataa
    18301 accatggctc accattaatg acgattaccc gtatatcggc ttgagattcg aaagaaaaaa
    18361 tggacgtgct ttttgtagct gtcatagtgg ttacctttta gtctggttaa tcaccactac
    18421 cgacgccaat cggttggtgg tgaactgtgc agggttggcg taaccggcta aaaggacccg
    18481 gcgcaccttt cggtgccccc acacagccca ccataatacg aatgtggccg tgctatacgc
    18541 ataaaaaaac cgcttgcgcg gtgaatgcgc cttttagtaa tccgggacgc caatcccggc
    18601 actggatttt gccagtgccc gattactatg gcacaagagg agtgcggtgt aaatttaccg
    18661 caaaggtaat gatagacaca gacaaacatt aaaatcaacc atatttggtt aatgtgtgta
    18721 aaagagccag cagcgagaaa ttgtgccgcg acgtaaaata acgagcatct gctggcttac
    18781 aaccagcgat gtttcaaatt tgtcactact atcaacgtgc cattacacgg cgcagagctt
    18841 tatgtcgtca atcacaacgg cgaaccgtac accccaatga aacctatcgt tgaaggcatg
    18901 ggtatggttt gggctgctca atttgttaaa ttaaaacaga gatttgtcaa aggtatttcg
    18961 gaaatcgaaa taccttctgc tggcggtaaa cagttaatga tatgccttgc ctttcgtaag
    19021 tttgcggctt ggctttcaag cattcagcca aacaaagtct gccctgtaat ccgcgaaagt
    19081 attgaaacat caaccgtatc gatatcgaca cggttgatta tgacggtaac ttatttccgt
    19141 gtgtactatt tctcccgcca ctaactaatt atatttgtct ttaaaaattt catggaatga
    19201 ttgagagtaa gacttgccat acttcaaata acattcttca tccaactttc ttaatgaact
    19261 tcgaacctgt tcgtggcata cagcaaaaaa aacaagtccg ccgcctatta atacccctat
    19321 tgatattggg ttcgcaacat cccataaaaa atcggctaac agagcaaata ccccaccgcc
    19381 gccaataaat gcccctatag ctcggttcgt tttagcttgc tcatagcgtc tctctaactc
    19441 actaaactct ttaatatcca tataagcacc tctataaaat tacttcatca ccggatccac
    19501 ctggtttatt agtggcgcaa tccagaacag atgttttatt attgtgaagt tttcattgca
    19561 cgattttcag ctctgaattc aagaaccgtt tcaatatttc tttccttcag catatccata
    19621 acatttttat tcatttgact atcactggtt aataactgat aaacgtttct tttctcttta
    19681 tcagaatttt ctttaacagc tgatttgcat gacaaatgct tattgaaatt ttctacatcg
    19741 ctagtacatg aatttacggc tgcggatgaa atatcagacg ctgaagaaac accgtcatct
    19801 aaacgtttta tagcattttc tatacatgag ttaagggaat aaacgacaac tgagcgatac
    19861 ccttcagacg cacaccattc taaatttctt gaaggatcga gtggttttac ttcgctggat
    19921 tgaattaact tgtcaaacac tgacttatat tcaatctgtt ttttatctat agcccatacc
    19981 tcagtagctg atttataatg cccagtatgc ttattaacat caaacccatg ttttataagc
    20041 aaatctgccc atgaaagatt tattgattca ttgttatgag gccatttccc tgtcagaacc
    20101 gcccccatag accccatata tccgccatat gatggtatag caccatggct caataacttc
    20161 tcagcaacca cagggcaatt aattacatag gagacgtaaa gcccattcca taaagcccct
    20221 ctatagtaat cgccgcgatt aggttctttt aagtcgatag cctttgataa ttgttcacac
    20281 gttttgcatg catcaaagtt atccttattg cattgcaatg aactggcggc tgtaggattt
    20341 acagcgacta ttgaaagcac aatgccaaac aaatttattt ttttcatcct atttcatctg
    20401 ctcttcaact ttattcagta atggtgatat cgcccacagg ttctgaaaag gtagcatttt
    20461 acggaccgcg tgggtttgct ggctgtcaaa ttctccgtta agtacaccat tcgcaaccgt
    20521 cgcggcatca ccgccaagat caaaggtagg accaagtaaa gcaccaatag cattacgact
    20581 ctgaaacctt gataccggag gcgcaccaaa catcgcgcca agaccaaacc taccgccgct
    20641 tatgttctca acggtattca gcggctcaga gagccagcca agcattccgc cccggtcgat
    20701 cccctctttc acaaggttat tccagctgta gtcgatatcg cgaccgctta acttctgttt
    20761 catcatatag accattgagc caagcgcaat cgtgccaagc gcaccaagat agaatgcagc
    20821 atcgccctgc tggataccag ataccagcac cctgttatgc tgtgcgaaga taaacgtttt
    20881 gaactgcgtg atcatcttcc agccttcttt actaaaaaac agcggtgtat cacctacgcc
    20941 aggcgttaca atcactgagt ctacatcttt cagcactgca gactggaaaa tctctctagc
    21001 gaaacggtca tcccacagat gactatgccc ggttaacagc ccgtccatat cctctccgtg
    21061 cttcccgaat tgctccccga ttcggcgcag aacatcttca ttgatgccga cctgtgccat
    21121 cttccgcatt tcacttttgg agagcgtgcc accagcagaa acttggcgag ccgcgtcaag
    21181 tatcctcgac tgcactatca tcccagacca tgatttaagt gcgctgttcc actgattcat
    21241 cagcgtccag ttaccgaatt tctgcgtcat ccagttcaga cctcgctcag cggcgcttct
    21301 ccggctatag gggtcagtaa gatccgctat agcctttgta cgcgtagaca ggacataatc
    21361 aagcccaact gccatttctc gcaaatccct ggttgcaatt ttcactgagt ccatattttt
    21421 aagcatgctt accattggtc cgagagattt tctcaggcca tgctgcatca tcggtcgcat
    21481 cagatcagtt gcagcggaga cggtcattcc accaagcaaa cggaggaagt taatattcct
    21541 agcaactcgc ccggcacgaa caaagaaact gcgtggatct tgaggtgcgc cgtaagtacc
    21601 aagcagtcgg tcacgcatag ccgtaatatc cctaatatca gcctcccgtt gcttctcaag
    21661 agctgcacgt cgtttaggtg ttttagcctc ttttattagc cgggtatatt cctcactaac
    21721 ctgacggatt tgctccccca tatctttacg gccaaactgc gcagtcagct caatttctgg
    21781 tgccacctgc cggagataac tttccatgat gtagttaaca tctgattcaa gaaaatcttc
    21841 tatacgctca tcaggaataa gcagcgttcg gcttttagtg aaaccagccc gaccaacgag
    21901 tctctctggg ataatatcgg ctggtacaag cccggaaggt gcgcctatta ttttattcac
    21961 gatctcgtca gcagcgtcct ctgcttcctc tcgggataga ggctccatct gcttcagtgc
    22021 tcgctcgcgg cttgcattca gccttgtggt tgaatttgcc cgtttttgca gtcggcgaag
    22081 ctcagaacga tatttccgtg gattatccag caactccata tggcgctgat agacaggaag
    22141 ctcactcttt gcctgcgcta tatcatcaag gcgtgtttta aggtcagagc tttctttcat
    22201 cattcttgcc tgaagttttt ctgatgaagt ctcggccaac tctttttcta ttcttgtaag
    22261 acgcgcctgt gtgtcagtct cctgagatat aagcttattt cgtttatcca gttcttccat
    22321 gagtagaatt tttttaccag accatttctc cgcttcagcg atttcactag cgagagcatc
    22381 agcgcgcggt gctgattcct ctgcagtttt tagcaatgaa tttatctttt caattcgctg
    22441 acctgctttg tcagcacctt tggcactaat cccttgtatc cagttggcaa ttcgccctct
    22501 gaattcagtg cggtcggaaa gtatcttatc gaacttataa atgcggggaa gataactctt
    22561 cgccgtcacg acatcgatat cctcaggaag gatccccaat tcctgcatac gggcttttgt
    22621 ggtctcaaaa atggggcgga ttctggcggc tgcttgtgaa acctcaggaa tatcactctg
    22681 atcaccacgg cgcatagcca tgccaacagc ttcattgaaa tcaataaagt tcatcctctt
    22741 cacgccgcgg gcgctgacag atttgctgta ctgctggtaa gcatcacgag tagcttccat
    22801 ctgcttataa agcatggcgt cgtattgctt aatcttagtc tcgactgccg taaacgtagc
    22861 caacccctca tcatttttgg cgaagaaata gttattttcg gcaagctgct ggttaatctg
    22921 acgggaaaca agagatggtg attgcgccaa gcggccagca ggagtgacac tcaacgtttt
    22981 gttagcaagt ccaagtccag caagctgttc ctgatcgagt gtggtattga aaacctgagc
    23041 tgcaccaatg ctttgaggag aatccatacc tcgcaaatga ttacctactg agttaaccac
    23101 tgcctcgcgc gcgctaggtc cagcaagtag ctgtgcacca gcaccaagga tcccaccaac
    23161 gagagcatca acaacaacgt tcgatacgct ctccatcggt gagcgagctt cctgagtggc
    23221 ctgcaatgcg gcctctgaag caacactgcc agcagcattg gctaaagcaa aacgtccggc
    23281 tgtttctgca atacgaccgc cacgaacgac agcgccgaac ggaataaaca tagaaatcgc
    23341 attgaatgga tctgctaatc tcattgctac agaagagact gtaccagcaa atcccaagcc
    23401 tgaattgtat tccatgtcag ctctctgctg atcgattcga tgtttaattg ccattgtttc
    23461 ttcatgcgaa ccggagttga taaacgaatc tgcaaaatct tcatagcctt taatatctgc
    23521 tgcatcgtta tcaaatgggt tatatccttc aaccctgtca aactgactga aaggagcact
    23581 ggcaataaag ctacccagcg tgttatctat acgaaatgct gcttgtctag acctttgaac
    23641 gcgttgatca ctggtaaatg ggttcacagc agaaagcaaa gaaggtgttt ccatatagaa
    23701 attactgtca tcaggtgctg ctatttgctg aataccctcg ccaagcaact ctttaggatc
    23761 ctgttcatat atcggcatta tttgccccct gcgtatatat tgctcggaag gtaattggct
    23821 gaaccataac cgaatggttt tgtcagatct ggaggagtat atccatcttt attgctgaac
    23881 tgcggcagcg gattgccttc tctccgcact ctagcctcat caacacgctg ttgctggaac
    23941 tgaatggttt gcctgtacat tggagatgtc agctgatccg gcttgaaacg aacagggaga
    24001 ccattttctc caatataatt tctcggttct atcgctccgt ttgcgtcagg ctgtaaaacc
    24061 ataacagcat aactcctatc ccttgccgta aggccatcag aaacaagtat taagtccgta
    24121 tcactgcgag gaccgccaaa ggattttgat ttaagctcgc gtttttcctg ctcccactgc
    24181 ccctgtatcc agttaccagc accattattt actccgtaca atgcctcagg tgcatacttc
    24241 ataacctctg ctttgccatt aaccgtagaa actccccaag tggttctgat catggcattg
    24301 gtcattttct cagcctgttc tgcatcgcca cctgtctgta caaagttagc atcgtaaatt
    24361 gtctggtaat ctcgctgata ggccgcattt gattttcctg gatcggtaat atccggagac
    24421 cacgaaccaa aggaagtcag actgctggcg ttattttgtg cagcagttgc cctcgccgcg
    24481 acatattttt tgtctcgcat ggcagtggaa agcatctgtt tcattcggtc atcctgttgg
    24541 aacacctggc tgtaagccat atcaacagcc ttatcctccg gcacgccagc gcgggaataa
    24601 tcgtaaacct tgccgtaaaa tgccatcgta cttttatcaa gtgttgccgc tgccgccgga
    24661 ttattatcga ataactgacc gtagaatttt gccatcggga caaccagcgc aggatctctt
    24721 gatgtcgctc cactgttaag cattgtttta atctgagttg gtatcatgcc gcttttagtt
    24781 gtgacggtga ccagtgtatt gatgctctgc ggatcagata tggaaaacga aggcgcgata
    24841 tcctgcgcga aataacggtc taccgctgcc tgattgtttt tgtcgttcgg gtccagcggg
    24901 aagttatttt gcattgaaga cacgaacctg tttcttccct gctgaatctc ccactcccta
    24961 tccatctctt taaatttggc ctgcattttc tcccagcgtt gctggttagc tgcaaatcca
    25021 ggagcgtttg gatcctgtgg acgtaaacgt tcaagaatgt cttgccgtcc ttctggagtg
    25081 aggtctttag cggcaccaat gacacctcca tattgtatct gcgcctgcat atccttccac
    25141 ttcatagcgc caatgcgcgg accattggcc cggataaaat cgtcctcaga aggtaacttc
    25201 tcaggtttca atccttcatc aagggctgaa tatgcatctt taactacggt gctaagctgg
    25261 tccgcatact gctggcggta ctgatttctc agctcattag cctgcctcaa tgcctgtatt
    25321 tgcatttgag ggctcatagc atcaaatgcc gcattgcccg tataacgctt aggtgaatca
    25381 aggttagtta gaccaagggc tgccgagata ccagtttcaa gctgttcggt gctataaggc
    25441 atactgccat tttcgtgttt aataatccca gcacataaag cagctagtgt ctttgggtta
    25501 gagatatcaa gctgatcatt ctccccaaca ccaagctcac cacacaatgc cctaatataa
    25561 gcatcagtat tattaccatc actagccgga gcatagcgat taacaatctc gctaacggtg
    25621 tcatagcctt gacgctggta agacaacata tttttaccca acgcgcggat tccatgctca
    25681 ggggtagcaa acgttgcaaa acgtccatcg ctaccgatct gaccttccca cgggttagat
    25741 ttgctcgctt caatattacc ggggttatta ttacgtaaac cacgagcatc caatgaatta
    25801 ccatgtgata ttgcacgact cacaccatca agatcccctg gctctccatt aacctgaaga
    25861 aactcgttgt atttttgagc gatatttcct atccatgctt gctgccccat ttgttccttg
    25921 agctgagttt tctgctgaac acgccactca tcaggaagcc catgcgcatc agcgtattga
    25981 tcaatagatt caaatcgctg cttggctaaa tcgacaaatg cttggttatc gctatatagc
    26041 cccgcagact gagtgacagc caatgcattt cctgacaaat acgtttgatc ttggaattgc
    26101 tgaaactgcc caacttcata tcgacgtgcc tgattgtaat aagactgcat agactgctgg
    26161 agttgaaagg ataatttatt cctttcctca ctttcaggaa ttgagcctaa taatgcctga
    26221 gccctttcct gcatattttt cataacagcg tcactctgac caagagcgtt tttaccctgt
    26281 ttagaaatca gcccattttc agggttgtta atctggtcat ctgcaaattg gttaaattgc
    26341 agtaacgcct cctgggccat agcaacattc gctttctgcc tggcttcacc atatgccacc
    26401 gcatactgat ctgcgacatt cgccagcacc tgacctgctt gaggaacatc gaaggtctga
    26461 aaaccaccgg tttgcacacc acgactttgc acctggcgtc cggatgtagt aggaacaaca
    26521 ggcatcagta acctcctatt ttgaatcggg agtcagaatt cataaaacct gagttagata
    26581 acattggcgt gtttccttgc ttactaatcg gattgatact tccgctaccc aacttatatg
    26641 caccgtatgc ttttagtggt gccgttaaca aagtgctggt catcgatgat ttagcagccg
    26701 actgagcagc agccccctgt gcctgagcat tcattccctg aacctgatac ccatatgcct
    26761 cacgctgagc attattcact gtcgttaacg catcaagagt gccgaactga gcattatccg
    26821 caaaaacgtc aagagctgtt ccgctactta attccgcacc ggtagccccc atagtggccg
    26881 ccgcagtgcc tgagcgttga cgcatttcac gacgacgctg atccgcttca atattcccac
    26941 gattgattga atcctgtgcc tgagcttcag caatttcagc attccgatca gctatggctg
    27001 actggtattt tgcctgcttg ctctggctgt acattgacgc ggctgtggat gccactgtga
    27061 cggcaaccaa agcgatggct gggttacaca ttattttctc tccatgtgaa atctgtggaa
    27121 attaagacca agagcaccat aaggcgcggc ttcttcaagc ctgaatccaa gccagtgcag
    27181 ccatgctttg gcaacatggt ttcgctcgtc gacatagttt tccaggcgcg gataaactgc
    27241 cagcatctgc tgcaatacag ggcggcagtg gcgaagaaat gtcttctgat atttttcgat
    27301 gcggctggtt ccgaccagcc agggcgtacc attgccaccg atcattgacg ccggagatac
    27361 gccaaacatg gttaccagtt ctccgttcgc aaatcctgac caggccatag tcgcagtacg
    27421 cagaccaaca cgcagcgcat cttcggtagt catcagtgat accgcataca gttcgtcaat
    27481 atcagcctga cgaacatccg gcaaaatcat ctgaagatgc tcttcggttg cgggaataat
    27541 ttgaacatcg atcatcagaa tcccccaaca gtaaggcgag gaataacggc aagaacagac
    27601 agcggcaacg gatcaagctg acggattttt acacgtccgt ttttgcccca gttactgtcc
    27661 agtttcactt ctacttttcc ggtagcatca tcaacaggat catcgtagaa ctcgaattca
    27721 cgctgtggat attcgtacca tttaccgccg ggcgtagtcg cccagatgcc gcgactggca
    27781 ttcacaacca gagtaacgga cgggatcacc tgttttttgt ccagcagcgt ttcctgtccg
    27841 ttaatgttga tatccagtgt ttcgaattca gcagttattg gcaggccgat gtgcactaca
    27901 gcccccggag attccagcgt gacggcacct ccggaaacca ctttctgtgg ttccacgttc
    27961 gcatcagaga ggatgtttac ggtctggcct tcaagatgag acaagccgcc aaatgtccgg
    28021 cgcgccatct gccagttcgt ggtggccaca ttcctgaggg atggcgggac gttcctgtta
    28081 gcacgaacca ctacagcggt attgctggtt acagaaataa tgtcgcaacg taattctttt
    28141 gacacttcat cgccagtatc aggatcagtt ccggtataag ggaactgtag ttgcgcgccg
    28201 acatcactac tggtgaagta cgcaccacca gaaacactga ttgtatattc cgcatggtaa
    28261 tcccattcac cagaaccacc agtgatggtc atcgttctgt cagacgtatt tcttccatca
    28321 tagctaaggc cagaatcaac aaagaaagca tcttcatcgc tggtaaataa acggctggac
    28381 agtcgctcga tgtatctcac tgtttgcccg ttaacggttc ggttaacgac gaaatacacc
    28441 gcatcttcat tgccttcgct gatactgcat gtgctttcat attttccggt actggattgt
    28501 ggtgcccatg caaaaacctg ctgatcacgc aaataggtca tcaccagtaa tttaccgtca
    28561 tcacgaatgc agaaggcact ggagtaaggg acaatcgaga agcaccagtc aacaatgctg
    28621 tgcttctgaa aaagatgatt ggcaaggatg gtcaggtcgt tcccctgata gccgtcaaca
    28681 tcgaatgagt aggccagatc acggacaacg ctgcctttct cctggacgaa cagagcaata
    28741 ttcgccacgg caattggcgg gacgttgctt gagccatttg atccctgaga gctgaatgca
    28801 aatgatgatg gggttaacac tttgttctgg tcgccggtga tgacgtactc acctccggaa
    28861 gtcagcgcca ccagagaacc aacatcaatc aggtggcgga tatcattaac ctgacgtccg
    28921 gcataggtgt agataattct gtcgtcatcc tgcgtaggat tgcttttgcc aaaatcctta
    28981 taatccccgg tacggctggc ccagatagtc tgaggaaacg cagtcgatgc ggcgaagtaa
    29041 agacgttgtt gataataaac aacagtgcca ggataaccat taacactgtt ccaggcatat
    29101 ttagcccatt tatagctggc attatcctcg ccaacgacct gcgaagggat ataggaaatc
    29161 acctcagcag ttgcagtagt gccatttgca gcagtgatac gggcaatgcc aaaaccactg
    29221 tgcagatact cccactcaat gccagtatca tcatcaccgg atccgcccca gccatcccat
    29281 gatgtgcctt ctgtatgcga agggcgcaaa gtacctgttt tgcctgctgt aacggcgcga
    29341 tagtagttac tgtctgcacg gcgaatatcg ccaatcgacg tactcttact ggtttcccat
    29401 accggcacag aatccactgc aggctgttcc agatagaaca atttgcctac ctgctccgcg
    29461 ccaaaaatag aggcgcttgc cgttaacgta attgtcccgg tgctggcgct ggcataaacc
    29521 gtcactgact cgtcaatatt gatatcttca aatggcccgt tcttcgttac cacatcaacc
    29581 agttgccagt tgtcatgcgc atagcggcgc aactctttcg gcgggtatgc cggatgaacc
    29641 agcgtaagca cgtctgcgct ttgcgtgaat ttaattcgga acagatcggc ttcagtatat
    29701 ggcgtggaaa tttcataaat aacattgctg ctgttcagca ccaacgcacc atctttgata
    29761 acgcgcatgt actggtgtcc gaactccaga gcataggtct gaaccgtcga gaactggaac
    29821 gggatcaggc ggcatttccg atttgggtat ttggcggcac cgacaaaacg cgtaccaggt
    29881 cgattctcaa cgccgccata ctgccgcacg ataaagttat cgcacttgcg caatgccacc
    29941 tggtacttcg ccatgtcgat acgaccgtac aacgacggtc caatctcacc accggcaaag
    30001 ctgggctgta tccaactgat agccatcagg acaacctcgc aatggtaaac tcgtcaaccg
    30061 gtggctgtgg ttcctgtgat tcattctggc tatgcgagcc agcactaaga atcacgcgat
    30121 tgtacatatt gagggcaaac gtaccgaggt ctgcattccc agtcagcgcc atgttaatag
    30181 ctgccgcaag acgccaggcc aacgcctcca taaaaatggc atcaaacatg ttcacatctg
    30241 taacgcgaga gacatacttg agccatgcct gaggctggtc tgtgtagatc aactttcctg
    30301 ttccgttggt gtctacacct acttcgtact gaacgcgcat tgctgctgtt ggattgcgta
    30361 caccaggaag cataatttca gtaatgcgca gacaatcgga cgggtactga tacgcatatt
    30421 cccagtcagg cggtggattg ctcgtatctg ccagcgccac gcgtttggta gcaaagttcc
    30481 agtcaaaatc agaaagcaca gcatcacggc aggcctcaaa gtgcagcgaa cattcccccg
    30541 cttccttgct ggcttccgtc aggctgttaa tgctgcggct attgccaata ttggacagcg
    30601 cacgattgca gatctctact acagaggcca ttactcaccc ccattgccgt acagggtttc
    30661 agccgctgat ttttctacat ccccggaaac aggagcgatc gccatatcag tgatctgcag
    30721 atcggcgctg cgattaacac catcgtcagt ttctctggca gacaggcctc gaataacagc
    30781 ctttgcagtt atcatcactt ctgttccgac gccctgaggt tgcgccttca gcttattcaa
    30841 tgtgtcgtta ttaagagtga tgcacagccc ccacgggtat tcatcgcgag ttctggtttc
    30901 tccgctctca tcctggtagc tgtcagtgcc ggttttgagg tttacgagtt ccatatacac
    30961 tcctgcaata aaggggccga agccccttgt ctgatccgcg aggcttacac gcccagttct
    31021 ttacgcttat ctgcgatctt ctcgcggagc gtttcggctt tggcgttatg gtgtggcttc
    31081 tcgttaaaga gcaattcgta ctcttcacgg agcttatcca gttcaccatc atctgacaca
    31141 tcgttgatga ttttggtgct ggttgctgcc attgactctt ttcctgcaac ttttgctttt
    31201 gcctgtctgg ctgcatcgtt aacaggttcc agtgcgctac caggctcacc ttcgtattcg
    31261 atttctgccc cctccggcca cagagtgtta tggatatgag agaggcgcag aacgcggtat
    31321 cttggtttct cacctgacat caatatcacc ttaaccagtt acttttgagc ggatcggata
    31381 cggcgtattg gcatcaacat caagattgat acccgcagtg aatttgccag ccgttagtgg
    31441 gccagttgcg acggagtagt taacacgcag atatcgctga acaccggctg gcacctttgc
    31501 agaaacaact cgcttacctg ctgtcagggt ggcctttgcc agtgcgccac tatcataaat
    31561 agtggaccat gagctgttat cctcactcgt ctgcaactgg atgtttacag ttgcatcacc
    31621 gcttgctgcg gcggctgtgt taaccagcgc ccaaaactca agcgggtaac ccacgccgat
    31681 atcacgacgt tttccgtcaa ttggaccgag atcgattacg tcagtagaag ccgcggtatc
    31741 agttaccgcc tgtgcttcgg agaacatcaa cagtttgtcg gtgatcatct tctttctcca
    31801 ttagtgggtc tgttacgacc cacaggttaa taacaggcgt tacaccacgc gggcttctgt
    31861 ttccagaagc gcatcagttt cacggattgg tacaccacgg aatgaagtcc accactcgcc
    31921 ttctgtctct tttacgctga tcgccagaga tgttttctcc agagattgca gatcaagagc
    31981 ctggcctaca gtgcggttca tgtagaacac cgggcgaccc atgccacgat ttggaatgcg
    32041 atgcagtgct ttaaccatca acttcgcaat atttgcggca gaggaaggtt ctgaaagatt
    32101 gctgacatcg atgtttgcaa tgcgaacaac ataacgccag tcacgcagag caagtccgtt
    32161 atcccatttg taatgggtgc gatagccttc gtacttgccg ccattagcat cttccagtgt
    32221 cacctggcct ttatcttcca tctggatgcc agccttctgc cctttcggga agatgccatg
    32281 cacggtgttt tcgccccaca ccactaacca gattgaggtg ttatctgtac ccgtgccacc
    32341 agcatcaatg atgttctgag cattacccgc agacaggctg gaatagcggg aggacagtcc
    32401 cataaactgc tgagggttaa cgctggaatc accataaaac agcgtctgcg ccatctgctg
    32461 attcatcgct tcaataaatg cgcggtcttc agacaggcgg aattcggcgg tattgccgtt
    32521 cagatcagcc agtgacttat cgacttccgc ataggtttcc agcatgccaa cggaatcggt
    32581 tacctgtact gtggttgatt tgcttggctg tacgccatag ttcagcaaac gccaggtagc
    32641 tgaaggtaaa ccagaacgaa tggtggttcg gtgtccggta ggaaggttcc cttcgacaaa
    32701 aggcatatcc tgaaggatcg ggttagtttg accgagaagc tcgataatct tatcgacttt
    32761 cccgtttgga tcgacgcgct taccccagtc agccagcgtt agcgcagtta agcctttaac
    32821 agccattgtc atttcctctc ttatttgcca tagagcactt cggccgcact acgctggcct
    32881 tcattaccac cggtgaccat gccatcttca gacatcgcct ttccgatttt cacgaacgtt
    32941 ttgaccagat cagggtgatt acccagcccg gtggtgttca gatattcttt gagttcaggt
    33001 gtcccgaact ggtcaagcgc acgctgtgcg gcgctaaggt tagaaatcaa cttgtcgcca
    33061 ccgatttctt tgtcagcttt tacatcagca gcccactgct cggttgtttt ctgccaggct
    33121 tctgcctggc gctgctgaac acctgccaga atcttcggat aagcatcaac cagcttttgc
    33181 gcttgctcgt tggtcaggtt tagttctcgc gccaccggct cgaattcctt caacgcttct
    33241 gtatccagct ctacgccttc ggcagcctga aactcgtact tctcaggcgc accctctgtt
    33301 ttatcgccgt cctttttttc atcctgctta tcgttttcag gctttttgtc atcagcaggt
    33361 ttatcgccat cagcaacagg ttgtggctta tcaccttccg gttgtgatgg atcaccaact
    33421 ggagcagggt tatcacctgc aggcgctgac ggttctgacg cagccggagc tgctccacca
    33481 tcgactggtt gctcattgca aagacggcga tacagcaaac gctcaaataa attcatgatc
    33541 actcctgttc actggcctct ttggccatct tcaaatactg ttcagggcaa tgcgccataa
    33601 cgcgctgaaa cagttccagc gccagattgc gttgcccctc attaaatgcc atagccatag
    33661 cgtccatcgg tgagatagcg gaaaacacac ggcctttctc cagcaccgac cagacaacgc
    33721 gacgcccctg ttcactgctc atgacaaagc aaatgtcatc aatttcacgc tgtgccatgt
    33781 cacgttgctt acgggcgttt tcttctttca gttgatcgtc ttcgtaatct gtcattgtga
    33841 ttgcccaccc tgaccactaa ctgcattcgc catagctgac aaaacactcg gatccgaagt
    33901 tttagcttcg cttagcgtct tggcaccctg tgccgccgcc atccccatcg ccatcatttg
    33961 ttgctgctgt tgttgctgtg cccgttgctg gcgagcctgc tcaacctgtt cctgcggaac
    34021 aatgacggtt ggagacactc cggacatatc agcgaatgca tcgatcgcct gatcaacgtt
    34081 gagtttgtcg agagcttctg gtttcgcttg cgcaagttga ccaatgaagt tgaccgtaga
    34141 cgccagactg gacaggccga tagacttctg cgcctgagcc atgacggaaa tgtattcgac
    34201 cttcaggggc ataccttcca tcgcgtcagg cggtggcggc agcatgtttt tacgcaccat
    34261 catcgagaaa gcgcggtcaa tgagaggatt aagacattcg tcgttcagac gctccagaac
    34321 cggccccaac atcagaagtt tttcttcttt catttcgatc accgcttcaa caggcatcga
    34381 gcgggtattg atgttctgca acatcatgaa cagatcgaca aagtaggcgc tgttaatgat
    34441 ttgacgggtg tcctgaatgt ctgccaccaa atctgctgta ctggggttaa ccagataagc
    34501 aggcctgaaa ccatcctgac cagtaatctg atcgatatac gtgatgtcgc caggaagaag
    34561 ggaggcacgc tgattcttga gggaagtcgg agcaaccatc ggcggattgg tggctttatc
    34621 aatcaactgc gacttgcgct tctggagaag ctgcaatgcc ttaacaggtc caagcgccag
    34681 catacccggg catgatgatc cataaacatc ttcgccgtta acttcccagc gcggagccat
    34741 aattggaaac tcatcgaatc cggactcacg caacaacttg tcgttatcgc caccaacctc
    34801 gtaataaacc gatttgaatg gcttgttctt gctatccagc ttcgatgtat cgcggtcaat
    34861 gttcgggtaa accgaatgca tcacttcaat ccacttctcg taggttccgc tttcccacat
    34921 gctttttacg gattcgctga cgttatttag cccgaactcc tgaacaagct gacgaacagt
    34981 catagagaac ttgcgaaaac aggtgtccac actgccacga ggtgagttag ccaggtagta
    35041 actgcctatc gggaatggca ttgtgcgaat gatgtcctcg tcatcctcca gcactgccat
    35101 tgcaccagtg ctgtatgtgc cgaggcttcc gtataactgc ggcagcgact gatagagatt
    35161 cgacttattg aacatatcgt tcatgcggtt ctgcaccgcc tcaagccaca acttaacagg
    35221 gccataatcc atcatttcag gatctggcgt agccaggcga aaccacggac gcgcggggct
    35281 tgtgatgcct gacatcatgc cgctggcgag agtgcgcgcc gccatagtcc cggtcgaatc
    35341 aataatgcgt gtattgcgtc gatcgttacg gttaacctca gaagtcagaa agcgggaacc
    35401 acgcgggttg atgtaatcac tcaactcgcg ccagtgcggc tcgaacgact gacgctcgct
    35461 ttcaagttgt gcgaactgtt tgttcaatcg ctctttagtt gtttccgcca tttcaatgac
    35521 tccggttact gaccaagcag cgttttaccg ctggtattag cagttgatgt gtcgccctga
    35581 gaaccggtaa gcagcgtaga actacgacca gcagcagcgc gacggcgacg agtttcttcg
    35641 tcgcgggcat caacaacggc ggcatcctgc tcctgtggtg ctgcctgaac ttctggtgtt
    35701 gcaggcactg atggtgagct acccatgcac atatcaatga ctccgtacgc aattaaatta
    35761 ttaccaattt aaccacatat gatttattta tcgtagacag ttgacattta acgtgcgaat
    35821 tattaccttt caggtaacca aagagttcat tccggttact aacctgactg gcttgtcgtt
    35881 aaattgaaca ggtggagtga gcttttattt tgagcagtac ggcgtatggc acatgcgccg
    35941 atagcggtct ggatgcgttt aaggggcacc ctccctggct gtggcaaacg aaccaggtag
    36001 ccggaatgtg caagtcgagc ggttttattc cgcgcacggg gattcaccat cccggcgatt
    36061 cggtgtgacg cctcggaaga gacgagggta caacgatgag agcatttatg gagccgcgac
    36121 aaagtgtggc gccttaacag gctaagtgct ctcagcgttg tggcattagc tcagttggac
    36181 agagcaaccg ccttctaagc ggttggtcgc aggttcgaat cctgcatgcc acgccagaat
    36241 cacgcctaag gaccgtgatg ccagaagttc caggggcttg gcggtgatgg tttcccttga
    36301 aggactatca ccgccctttt tacagcagga cgccattgcg atgacttcat gctgtaaacc
    36361 agtacagcca cggaaggcat aactcattgc ttccagttcg cccggttcgc cgggcatttt
    36421 tttaaggtga gatcatgaaa acagccgaca tgctagctaa atatctaaat gaatggccgt
    36481 gcaaatatgt acgcattgtt cagggtgatg actcaatttt ttatggtgtt tttgcaggaa
    36541 atgaaatgct ttgtgaagca attccaggtg agcgacttgc cgggttaacg cttagcgatg
    36601 accatggaat aggagttact tgccatgact ggatttcagc gcagaaaact gaaatggaaa
    36661 aaggcaatgt gtttgatatt tctcgcgctg tatacgccaa agaaaaaagt gatgatgatt
    36721 acatgcgcga aaacttatac aacatgaagt tacaatgcct ggctgaagtg cttagtaaaa
    36781 gatctttact tgatgtggtt ggtgctgagc aggacgccaa ggcaatcaac gccgcattcg
    36841 ataaaataac cttctaacgc cgtgacatgt cacaatcagc ccgccgattc gcgggctttt
    36901 ttatgcaaaa ggatcatagt ctgtgatggc tttgccttgc tggttctgct gcccaggaat
    36961 tcgcagacgc ttcgacacag ggaaagcaaa cgtcagcagt agcgcatcgc ctttacccgg
    37021 cgaacgccca agccgctcct tgatatcttc cttcggttcg ataacgattt taccgtccac
    37081 acgaactttg tactctgctg ccgacaggtc gtccgctgtt tcctggtcat ccagcatgcc
    37141 gccgagcctc agccatgtct tgcatgagtt gaacatctcc ccacgcttgt tgagcatctg
    37201 cgggtcagta gacgcgccac cgaacggaac aagttgccat gtacgacccc agccgtcacc
    37261 gattgacttc agaccagttc cgtaaccgaa gtcgatgaac actgcgtcag cctggtactg
    37321 gtcttcaaag tcagcgatac gcttcgccat aatcagatcg tcagtggtct tgttgccagt
    37381 ccacagcacc ttactgtgca gcccctgccg caggtatatc acagcgtcat caacgcctga
    37441 gtatgccggg tcaacgccga ttatcaccgg agcatgtgca acctgcgcag cggttaccac
    37501 ccgtttcatt gcctcgtcag taagaccggt agggataaac tgcaattcag atgcatcagg
    37561 gaatatgccg cgcacacgga ttttaacgaa gtcgctatct tccccgtagt catcaaccca
    37621 tttctgcaac tgctgtttgt tagtgccttc caccgtccgg ctgtcaatct gcgcagtttt
    37681 ccagcggtgt ttatatttgc ggaaacattc gcggaaacgc ccggtgttac gtgtagggtt
    37741 tccgaacgct acccagataa tctcagtgtc ttcgtccgta agcgcaccct cagcaacttc
    37801 ccacaccaga tccgcaatgt tcgacgcttc atcgaatacc acgatgatgc gtttgcgctc
    37861 gttgtgtagt ccggcgaacg cctcagtgtt gtgctcagac caggggattg cgtcagctcg
    37921 ccaccgcttg tcgtgcccag ggtcattgct gtacatcgcg gtagcggtac aggtaaacca
    37981 gtctttcgtg atagcaaggt tcgaccactt gataatttcc ggccaggtct tcgttcgtag
    38041 ctggttgtcg gtgttggcgg tcaccacaac cttacaatcc tcgcaagtgg acatgcccca
    38101 gttgatcagc attgagatga atgcggattt accaataccg tgacccgaag cgcgtgccag
    38161 cataagcggc tgatagcgcg tctctggatt ctgcaggtga tcacgtatct ctcggaacgc
    38221 atcagcctgc cactgacgtg gaccggtggc atgtgccagt tcagtcccat cttcccccca
    38281 cgggaacgca tagagggcat agccaagcgg atcgtgagtg aaccctgcaa tatcctcgat
    38341 taactgctct tcaggagata acgctgtatc tgtcactgat taccatcctg acgttctttg
    38401 agtcgcttcc tggctgctgc tatgcgatca gcaattgtca cattcacatt aacatccaga
    38461 cgttctttga atgcgttgac atcaacatgc ttaccaatca gctcaaggtt cttcaccttg
    38521 tcaggccatt taattttttt gaggattgtc tctattgaat cctcgttcat gttcatgatg
    38581 gtcgatgaca gatcaaagcc actaagcgta gtgcgccaga ttttcggcca ctcacggatt
    38641 ggtttaaggc tcccatcgtc gttgaggatg tcgatcacgt ccatctggtc gatctccacc
    38701 aggcgcatga gaacgtaatc agcactgaca cgcattcgtt tgttgcgctc ctccatcaac
    38761 tcggcaatcc gtttctgaat gcgttcatcg cgcatcatga cactggcttt aactgccgct
    38821 gtatttgggg agaatcctgc gttaatcgca gcctgagtct ggttttcagg cgttttgatg
    38881 tatgactggc aataagcctc ctgcattgct gtgagcggct taaattgcgt tgatttgcgt
    38941 ttataggttt taggttcagc aggcatcata actaccgtgg taattgttac cgttgtggta
    39001 ataataccat gcaaaataaa gccgccatag ttggcggcag tattcaaaat ccatcaaatt
    39061 catcatgcat aatctactcg tgacatgtca cactattaat ttcgtttcat gccagccttt
    39121 agtcacccag cattgtgagt caccattaca cggacatgaa ttaactggaa ctctctcgcc
    39181 gcacttaccg caacgtgttc tgctgatcga ttttatacgc ccgtgcacgc gtgcatcatc
    39241 ctggcggatc agtaacgcta tatactcacc aaattcgtaa ggcgcacgcc cggggcgacg
    39301 cgtggcacag ttacgctcca gaatttcaat ttcctgagca tcaagcacaa tctccagctt
    39361 acgcacacca gatgcagctt gtctggctct ctgagcggct ttgcgctctg ctgctgattt
    39421 agccatcaat atttaccttt atcgcgaaca cctttaccgg tttatcaccg aagtgcggat
    39481 gtgtgattgt ctttatttca tatccgttat acgggacgtc aattctgcga ctgaagtctt
    39541 cgcgcttcgg atatcccttt gtgataatca ggcggtaata cttacggtta acgaggcgct
    39601 tattccagta gtcattacac aggcgatact cttccgtttt ctccccgcga atcatggcat
    39661 cgaagtattc acctttaacg gcaagttgca ggttagccac ggttaacctc cttcggcggt
    39721 tctggtagag gcatccagtg agttacatgt gccccgtaat gattccagaa cgacgcaact
    39781 ggcgcactgt ctccatcagg gacaacccag taatcgtgat gaactttatt attaagccca
    39841 tcaaacacca gatactcttt acaacttccg ggaatgttct caggcattcg ctcactacag
    39901 cttatccaac catccagagt taccggagtt ggtccatcga attcgggcat gtcaggacct
    39961 tttctgatag ctttagccag ctccagcggg tcatcgtaaa gccagtcgcc agtttgtggg
    40021 tgatttgctt ctgcaagctg cgcagcccat tcaagaccat ctttttgacc ttggagataa
    40081 tcaagtggca actcttcatg attacttgca ggttcggcac catgaagcat ggcggcgcgg
    40141 caggcgttcc agcctctcac ctctgcaata gcggcaacag catcaaccgc gtacatgcta
    40201 agaggattag gcattggttt ttcttccggt actactggca ctggaggggt ggcgtagagt
    40261 ggaactcctc cccctccacc agaaaattca ttgcgagcgt tatactcacg accatctgcg
    40321 tcatcacgca tccacgccac cggttctgct tccagcgagg ctaacgctat ttcataagcc
    40381 cggcgctcaa tattgtctct cacgtccagg ctgcctatgc gctctttgat ttctttaatc
    40441 agttctttgt cggtaaaagt gctcatatca atctcctttg gtaccaatgt ttacagcctg
    40501 gcaagcctct ttgagcaccc agtcaaccgc gtctttccat gctccggttt cgactggcgg
    40561 attctcgcgc tttacctgtt catagaagcg tactgcttta accagtcctt ctgatgtcac
    40621 cgaagctggc ggggccgtga ataacgcctg aatttcatag tttggtctgt cgttacaatc
    40681 ctcttttgtc gggacatatt tccagtcacc aacccactgc ttcccctgaa agtctgtaac
    40741 gccttttttc acgtagcgat atcgccatgc cactggtttt gcctgcccta ccttttcatg
    40801 cccttcctga taattaatct cgctcattca tcgccccact catcacaata tgcttcgacc
    40861 ggtgttttcc ctgcttcata atcatcacgc catgcttcag catcagcggc acttccaccg
    40921 cgtaactctg cataatccat taacagttca tgccattctt caaaactggc gttatattta
    40981 gttgaaccaa aatcagccat tttgttcttc ctcttcgtct tttatttcgt ggtatgagta
    41041 attgcagtag ttaaagaaaa tatctttagc ttcatcctgt atttcatctg gtgttgcatc
    41101 atcatccact tcgaattcat cctcgaaatc tccaccggct attcccgttt caataattat
    41161 tttgaatttt cgcatttcac taccgccctt tcggacggcc tcctgatgtt ctgagcaagt
    41221 gcattctccg ccgccagcgc attagcacgc accagttgca cttccagttg cgttgccaaa
    41281 tcgctgatca gctttgccac actgcgcata tcaacggcac cacattctgc tttcagttcc
    41341 gaagccatct catgcccggc ggcaactaac cctttgatat tactttccat ctttaccctc
    41401 gcttatccac ataacttatt gattacattg ataactaaaa agatcgtcga ttcagaactc
    41461 ttcgattttc catccgccac ctgctttctt tggcttaaca gttaccccga tgattcggaa
    41521 cggatattga tctgcggcga ctttggtttt caccctggcg tcgtcggtcc agaaaccttt
    41581 cacttcgtgc agttccatct ctccggtggc gagcatcaca gcgaaatctg gcgtatagaa
    41641 cgtgttatca gctaaccgca gcttgatacc ctcgaatcga taccaggcga tttcccctgc
    41701 acgtttacgc agctcaaggt gctggcaata cacagattct gttttgttca tctggcctgt
    41761 tttgagtcga ccaagagcct gtatctgttt tctcatgatt tacccctgag gtaattaaaa
    41821 accacataag acacgaaatc aatagagttt agaatatttt attacccaac aggtaattat
    41881 caagacgtaa aaaaatgcgc tatcgcgctg gtattacttg ataaatcctg ccgcctttcc
    41941 ccgcctgtat tcctccatca gccactgcgc cggtgttatt ccccccaggg tggcggcgtt
    42001 aggcatacac ccgaaacttc gccctggtgg atggtaaacg tctctccctg tgtccggagg
    42061 tgtactcatg ggttctggct ttgcctgtat gctgatcacc ggatcgggta tctgctgtcc
    42121 ggaagccacc tttttcgccc aatcatcgag cagcctgcgc gcgtgtttct caacctcaat
    42181 ctcgctaagc tggcgctgat acattgcacg gcgggtatca catacgaccc agtacataac
    42241 cggatgtcgc cacgggaatc tttcgggacc accaggatat aaactttttt ccttgctgta
    42301 ccggtgaaac tccgccatca catcgtcaat ggtgacgcca agaaccatct tgctgtcttt
    42361 gcaccacttg atgaattgcc caggcgacgg ccagaacgga gattcactgg cgcgggcgtg
    42421 gcgcatacca gcgttaacct gttccattgt tgtgatccca ttctccagaa acgcaagcat
    42481 ccattgctta cggaattcat taagtttgtt ctgctccctt atggtcgaaa cgcttgcagg
    42541 aaatgcagcc tgtaactgga caaatagttc attgaaaatt ctagcaacct gctccttttt
    42601 gccattgctg tcacgccgct cttcatgcac agcaacacca tgctcacgta agcgatcgta
    42661 ctcattgaga agttctggag ttgatttcat cccacacccc ttctatccag tcagtgttat
    42721 tccagtcaag ctcatcgctt ttcccggcgt tttttgattt tcccctgata tgatttacgt
    42781 gcctggcgaa tttttgttcc cactgaacct gcgtgaacac tttgccctca gccatccagt
    42841 aatcccggaa tgcagcaagt tcagcaggtg taaattccgg ttccggcagg gccgttcccc
    42901 acagcgcagc acgccgtcga aaatccggcg acggatgcca gccatcggtc atcggaaatt
    42961 tcccgatggg ttcactcagg ccatccagaa attcaggttc agccacctgc aacggcatac
    43021 cgttcgcttc actggtcgga gcaccctcgc gcacgtgcgc tatgtgtggg gttttatata
    43081 tatcttcctc ttcctcttcc tctggtaact ccttttgtaa cgctgttggc gttacttttt
    43141 gcgttactcg ttttcgatgc tctgccactc ttctattcgt aagtgcacgt tttttcgatg
    43201 attctccatt atgtcgctca aagtttggaa gaattagttt gccgtcatga taagcaagcc
    43261 atccgacgct aatgagggcg tcagcaaatc ctgtaataaa agcgagtcta tcaagtactc
    43321 cttttgtaac gctgccagcg ttaccgtcta ttgtttgctg gtcagcccat gcccatatac
    43381 gaaccagctt tccaagaaca gcatctggat caatacccag aatttctgct atctgaaaaa
    43441 tttcaggttt atcaggagtg ataacttcaa ccttaatcca gctgcttgcc ataggtttcc
    43501 cctcttgcac tctttagtgc acaagcaaat tcattacgat ggcggttggc gctattcatt
    43561 gcacattcaa cacatgttcc gttcagaaca tacctttcag agagatggcc gtgacggcac
    43621 cgctttcctg tgaaatagcg atttaacccg gcttttgcgg cctccattct ggttactatc
    43681 ttcaattttt ccgccccttt ttgttattga tattggctat tttgcacaat tggaaaattt
    43741 gatcaaccag atttggtttt ttattacctt tgaggtacga atagatatga aaagaccgcc
    43801 gggtggcggt ctacagaggg ttgtagctgg atatcatgag tagaagaagt atgccagttc
    43861 tgcttttgag cgcagccatt gtcttgtttt acaggcttta aaaagcccat tcatcaatac
    43921 tttacctggc attttgcgct tacctgttaa gtgagtctgg atatagtgac tcgtcgttcc
    43981 ggcttcctgt gcgaaggctt cacgctcatc cggagtaagt gcaagccagt gctttttgaa
    44041 atcgaaatgt ccgttatcgc tcatagctat tgcctgatat ttatttcaga taataaatat
    44101 tcacccataa ggtaacaaaa atcaaggata gttacccatg aggtgcattt acctgttggg
    44161 taatattgct ttaaattgaa tcatctactg attcatatat gaggcgattt tccagaaaat
    44221 gaaaagtatc caggacgtcc gcaggcaaaa tctcaacgac ttgatcgacc gtgaattcaa
    44281 tggtgttcag acgcggatgg cagaaaaact tggaactcag gcaaatctgg taaaccgctg
    44341 ggctcttggc aagaaggtta tcggcgacca ggttgcgcga aaaattgaag ctgccgccaa
    44401 taaaccacgt aactggcttg atatcgatcg ctcgctttct caggaaggtt ttcagcctgt
    44461 cggcccaagc gacattggtc agctggcggc tcacaacctg gaacgctgga tgagcgaaag
    44521 ccgcgacctt tcaactcagg gaaaacttca ccgcgcatcc ggcgtcgccc aggtgacaat
    44581 cagccgcctg ttaaacaatg aggtcagtgt ttccatttcc accctggaga atgttgcatc
    44641 agcattcggg cgtcacggct atgaattact gattcacccg cacgaccctg cgaccatcaa
    44701 ctatgaccgc tcgcgctacg cattgttacc cgaaaccgag aaagcaaaga tcgaaagtta
    44761 cattgaattt gtcatcaacc agaacgaaaa aaacaaacaa taaaatcata tttttcagta
    44821 agtaagccgc cttctggcgg cttttttatt gcctatacta ttacctaatg ggtaattttt
    44881 ttaactcata tctattgaca tcaaaccaaa tacgcataat tattacctca acggtaacag
    44941 accgaggtaa caagttatgc agtggaaaat catcaacggt tggtactgcg ttactgcatg
    45001 cggattcatg agctggaagt tccgcacctt acaggaaggc attaagtggg ctttcgtcag
    45061 caaagaagct cgcgatgtgg ccaacgataa cgagatatgg gagggctgat aatgaacgtt
    45121 aatcagcaga aaaatcttca aaaaatcatg ctggcattcg acaaggacta ccgcctgtca
    45181 gaacagctat atgaccgaca agttgaactg atcgagagca tccggcttca tcaactggcc
    45241 tcaactttcg acgctgtaac aggtaaaggc gttcgccagg aagtactgga ggccgctaaa
    45301 gacagtccag agttcgaaga actgatggat tcctaccggc gagaggcaat ggcaattatc
    45361 gcccgctggg atctggctga tcagcttgat gggcagaggg acgcggcatg aaaccgggaa
    45421 tttatttcga catcagcaac gaagactacc acgccggtga cggcgtgagt aagtcgcaac
    45481 tggacatggt tgccaagaat ccggcgcttc ttaaatgggt tcaggcagca ccagaagacg
    45541 aagagaaaaa gtctgcactg gatatgggaa ccgcattgca ctgtctgctt ctggagcctg
    45601 gagagttcga caaacgcttc attgtttcac cgaaattcga acgtcggacg aaacaaggta
    45661 aagctgacga agaggcattt cttcgtgata ttgcggatat ggggatttcg gtacttgatg
    45721 cagagcagtg gcggaaactg gagctgatgc gtgatagcgc aatggctcac ccggcggcac
    45781 gctggatgtt ggaagcacct ggttactgcg aagcatcaat gtactggaac gatgaagaga
    45841 cgggggagtt gtgccgaatt cgtccagaca aatggctgaa cgagcacaac gtgatcgtcg
    45901 acgtgaaaaa ggttgcagat atggaccgtt ttgcacgcca catcgaggaa ttccgctacc
    45961 acgtgcagga cgcaatgtac cgcgaaggcg caatgagggt tactggtcag ccgcatggtt
    46021 ttttctttct tgccgtgagc gaaagcattg attgtggtcg gtatccggta cgcgtgttcg
    46081 agctggatgc gcaggatgtc gatgccgggc acgctctgtt ccgccgggat ctgaatacct
    46141 atcacgaatg ccgcatcaat gatgaatggg gcggtgtgga aatcattaaa cgccctgagt
    46201 gggcacgcaa acaggatatg tacatatgag caacgacatc gcaaacatca acgcaccagt
    46261 agacacagca atcgctggaa ctgctgcaac tattttcagc ccagacggct tgaaccaact
    46321 gatgaaattc gccgaggtaa tggcgcaaag ccgcgtaacg gtaccggcgc acctcgccgg
    46381 gaaaccagct gattgcatgg ccgtggcaat gcaggctgcg cagtggggaa tgaacccgtt
    46441 tgccgtggct cagaaaaccc atgttgtgaa cggcacgcta ggttatgaag cccaattagt
    46501 aaacgcagtt atctcaacga tgtcgccaac aaaagatcgc atcaactacg agtggttcgg
    46561 gccgtgggaa cgcgtgatcg gtaagtttgt tgagaaaaca tccaaaaacg gcaatccata
    46621 tatcgcacca ggctggactc taaaagacga agaaggctgc ggtgttcgcg tatgggcaac
    46681 catgaagggc gaggatcaac ctcgagtgct tgagttaatg ctgtctcaag cacaggtaag
    46741 aaactccaca ctttgggcca gtgatccgaa acaacaactc gcataccttg cgacaaaacg
    46801 ctggtctcgc ttgcactgtc ctgacgtaat catgggcgtc tacacccctg acgaattaca
    46861 ggaaacggca ccgcgcgttg agcgagacat tactccgcaa acgaccactg ctgcgggaat
    46921 gaacagtctg atcaacgcta aaccagtgaa aaagcctgat gagcaaacgc gtaaagcgga
    46981 tagccgtgat ccagaagaaa tgctgatggc ctttaccagc gcagcgatga attacagcac
    47041 tgtctccgaa ctggataagg cttacaaata cattgaacag aaactttcag atgatgacga
    47101 actgctggca aaagccaccg acgtttacag cgttcgtcgg gaagaattaa acgaaacatc
    47161 tatgtaacca ccaccgcggc gccacgcgcg ccgcactgca accaagagag gtatttatga
    47221 aaggtgcatt aggtaagaag gaactcctgg cggtggtgcc actgtcatgg agcactatcg
    47281 accgtatgga gcgcgcaggg gaatttccta aacgctggta tatcactgac aaacgctgcg
    47341 catggaaccg tgacgaagtt gagcgttggc ttgatgaacg tcaggcagca agcccggcag
    47401 agttccaggg taaaaagcct cctgttcagc aacgtgtata tcgtcctgtg agcaacgctg
    47461 catgagtgcg ctgctaaggc actggagcaa atggtcagga tggtacttat tcctggcctc
    47521 tgtttcagca tggctttatc tgctggcatt aattttcaga gagggttgga ttaagtgaga
    47581 aagttaagcc gacttgaaaa atatcacatg aacaaggttt caatgcgccg tccttcaaag
    47641 gttatcgccg ttactcctgc ggcgatagag ttcgaaaaac gcgcgattga aagagagaaa
    47701 aaagggcagt tccgcattgc cgcccacctt tggcttcagt gtatggatgt tgcttctggt
    47761 gatgttgagc gtgcaaggat cgcggttcgc agggaccaat gtatcacaaa aggtaacggc
    47821 cttcgccgtg gagactatag cggtatagga tgttgcgggg tggtttatga ctaagaaata
    47881 cacgctaatc tatgcagatc caccatgggt ataccgggac aaagccgcag atggtaatcg
    47941 cggtgccggt tttaaatatc cagttatgag tgtgctggat atctgccgcc ttcctgtgtg
    48001 ggatttggcc gctgaaaact gtctgttggc catgtggtgg gtgccaacac aaccactcga
    48061 agcactaaaa gttgttgaag cctggggatt tcgtcttatg accatgaagg gcttcacgtg
    48121 gataaaatgt ggtagtcgac aaccagataa actggttatg ggtatgggac acatgactcg
    48181 cgccaatagt gaagattgcc tgtttgcggt aaagggaaaa ctacctccgc gcattaatgc
    48241 agggatcgtt cagtcattta ccgcaccgcg gcttgagcac tcaagaaaac cagatgtcgt
    48301 tcgtgaaaaa cttgtgcaat tgttaggcga tgtttctcgc attgaactgt tcgcccgcca
    48361 gtcgtctcat ggcttcgatg tttggggtaa tcagtgcgaa gactcggcag tgcaactaca
    48421 ccctggatac gcgttggata ttggcggatt aacaaatgca ttcagcaatt ctccgctgtc
    48481 accaacagac aaccaggggc gggagcgtgc tgcatgaaca tggcatcacc agcagattta
    48541 agaaaatgcc ttgaaactgc aaacatgctt gcacacagcg ggatcaggtt tgttccaatt
    48601 cccgctgtca ctgatgctga atttgcaaca ctgtcagcaa tattcgaaaa caaaattgaa
    48661 tcactggcag cagaagcaga gatggaagaa aatcagcaga actattaaac gttattcccc
    48721 cgccatccac ttctcaaact tcgacgggga gaacggaatc agatccgtat gctccccgtt
    48781 aatccaggaa tcaatcatat cggcccactg ctgcaacatg taggcgcgct gtctggcgta
    48841 ttccgctttg ttatatacgg cgcgcacacc tttctgctca tgtgccagag ccttttcaat
    48901 ccagtctgaa ggataaccag cctcatgcaa caacgtactg gctgtacggc gcatatcgtg
    48961 tacggtgaag ccctgaatat gctcaccatc ttcatttatt attttcaccg ttctgtcgat
    49021 cagagagttc agcgcggcat tagataatgg cttccggaaa ttgtaacgac caggaaccag
    49081 atattcactt ccaccagcgc acatctgcaa cccaaccaat atatcctgtg cctgtttagg
    49141 caggtaaata acgtgcgccc ggcttccctt catgcggtct gaaggaattg tccatgtcca
    49201 ttttttaaaa tctatttcat cccacgttgc attggtgaat tcgcctttac gaaccatagt
    49261 gataagcacc agctttaaag ccattttcat agtgcccata gcaccaatgg catccagcgt
    49321 gcggaagaac agaccaattt cttctggtgt cagtgttcgc tctcgtggtt taaatatggc
    49381 gatagacgaa ggtttaatgt cagccgcagg attaaacaaa ccatgaccac ggtcattggc
    49441 atgacggtat acgctgctga tgatctccct ggcctgcact gctgttgccc ggccgccgcg
    49501 ttcgacaatc cggtcacaca aatcacgaac catcgatgtg gtaatttcag tcatcatttt
    49561 gttgccaaga accggaagta tgtcacggtc gatcaccacc tgcttcattg cgcgggtact
    49621 gtcagctagg atgacatgtt tcatataact gtcggtatgt accgcaaacg tctcggcacc
    49681 acgaatcttt ttgataccgt cacgtttagc cgcagccggt gactggcctg ctttaagcag
    49741 cttctttgca gcaatcagtt cttctcgcgc ttctgccagg ctgataccgt cacgcccata
    49801 ctgcccgatt accagtgttt cgcggcgacc gttgatacgg tagtcatagc gaaacgagac
    49861 cgtgcctgac gtaagcacag ctacatacag cccgtcacga tcggagacct tgtacagttt
    49921 gtcctgcggc ttgaggtttt ttaattttgt atcggtaagc acaattcacc cgtatagaaa
    49981 ccattttcat gacggtatga gagtatacct ttaaggtaat accgtcacct gtaccgccga
    50041 aaaatatggt gtagagtgaa tagaaatgaa tacataaaaa caaaaaccct ctgtaaaaac
    50101 agagggttga gttagtatct gaataggaat gacttgctat gagttagctg ttaatcattc
    50161 ccactcaata gttgctggtg gcttgccgct gatgtcatac accacgcggg aaataccatt
    50221 cacttcattg ataatgcggt tggaaactcg accgaggaaa tcgtacggca gatgtgccca
    50281 gtgtgcggtc ataaagtcga tggtttcgac agcacgcaga gagacaaccc agtcatactt
    50341 acgaccatcg cccattacgc caacggaacg tactggcagg aagacggtga acgcctggct
    50401 gactttgtcg tacaggtccg ctttacgcag ttcttcaatg aagatggcgt cagcacggcg
    50461 cagcaggtca caatactctt tcttcacttc ccccagaaca cgaacgccaa ggcctggtcc
    50521 cgggaacggg tgacggtaca acatgtcata cggcaggccc agctccagac caatcttacg
    50581 cacttcgtct ttgaacagct ctttcagcgg ttcaaccagg cccatcttca tctctttcgg
    50641 cagcccaccc acgttgtggt gagatttgat gacgtgtgct ttaccggttg cagaagcagc
    50701 agattcgata acgtcagggt agatggtgcc ctgcgccagc cacttcacgt cttccagttt
    50761 cagcgcttct tcatcgaata cttcaacgaa aacgcgcccg atgattttac gttttgcttc
    50821 cggatcgttt tcgccagcca gcgctgacaa gaagcgatct tctgccggta cgtgaacaat
    50881 gttcagacca aagtgatcgc caaacatatc cagaacctgc tctgcttcgt tgagacgcag
    50941 caggccgttg tcgacgaata cgcaagtcag gtttttaccg atagcgcggt gcaacagcat
    51001 tgcggttacg gaggaatcca cgccaccaga gaggccgagg atgactttat cgtcgcctac
    51061 ctgctcgcgg atgcgggcta cagcgtcgtc gataattttc gctggcgtcc acagggcttc
    51121 acactggcag atatcacgca caaaacgctc cagcatgcgc ataccctggc gggtgtgagt
    51181 cacttccggg tggaactgta cgccatagaa gcgtttttct tcgttggcca tgatggcaaa
    51241 cgggcagctt tcggtgctgg ctacggtgac gaagtcggac gggatagcgg taactttatc
    51301 gccgtggctc atccagacgt ccagcagcgg tttaccatct gcggtcagag catcttcgat
    51361 accgcgaacc agtgcgctgt cgtttacgac ttcaacctgc gcgtagccaa attcacgttc
    51421 attagaagcc tcaacgtgac cgcccaactg catcgccatg gtctgcatac catagcaaac
    51481 gccgaatacc ggtacgcctg cttcaaagac atactgcggc gcacgcgggc tgttttcttc
    51541 agtagtactt tccgggccgc cggaaagaat aatgccgctt ggattgaagt cacgaatttg
    51601 tgcttctgtc acatcccacg cccacagttc gcagtaaacc cccagttcac gcacgcggcg
    51661 cgcaaccagt tgagtatact gggaaccgaa gtccagaatg aggatgcgat gcttatgaat
    51721 gttttccgtc attgacgctt attccgaggc aagtgaaaca gataatataa atcgcccgac
    51781 atgaagtcgg gcgaagagaa tcaggagccc agacggtagt tcggggactc tttagtaatg
    51841 gtcacgtcgt gaacgtggct ttcctgaata cccgcaccgc tgatacgtac aaactccgct
    51901 ttagtacgca gttcgtcgat agtaccacag ccggtcaggc ccatacagga gcgcaggccg
    51961 cccatctgct ggtgaatgat ctctttcagg cgacctttat aggctacgcg accttcgata
    52021 ccttccggca ccagtttgtc ggcagcgttg tcgctctgga agtaacggtc agaagaacct
    52081 ttggacatcg cgcccaggga acccatacca cggtaagatt tgtaagaacg gccctggtag
    52141 agttcgattt cacccggaga ttcttcagta cctgccagca tggaacctac catcaccgcg
    52201 cttgcgccag cggcgatagc tttagcgata tcgcctgaga aacggatacc gccgtcagcg
    52261 ataaccggaa tgccggtacc ttccagggct tctactgcat cagcaacggc ggtgatctgc
    52321 ggaacaccga caccagtcac gatacgcgtc gtacagatag aaccagggcc gatacccact
    52381 ttaacggcac tgcaaccggc ttctgccagc gcgcgggcac ctgcagcagt tgccacgttg
    52441 ccgccgatga tttgcaggtc aggatattta gcgcgagttt cacggatacg ctgcagaaca
    52501 ccttcagagt gaccgtgaga ggagtcgatc agcagaacgt caacgcctgc ggcaaccagc
    52561 gcatcaacac gctcttcgtt accagcgccc gcgccaaccg ctgcacctac acgcagacgg
    52621 ccttgttcgt ctttacacgc gttcggttta cgttccgctt tctggaagtc cttaacagtg
    52681 atcatgccga tcaggtggaa ttcatcatca accaccagcg ctttttcaac gcgtttttcg
    52741 tgcatttttg ccagcaccac ttcacgggct tcgccttcac gcacggttac cagacgctct
    52801 ttcggcgtca tgtaaacgct aaccggctgg ctcaagtcgg tcacaaaacg cacgtcacga
    52861 ccggtgataa tgccgaccag ttcgttttct tcggtaacaa ccgggtagcc agcaaagccg
    52921 ttacgctcgg tcagttcttt cacttcacgc agcgtcgtag ttggcagtac ggtctgcgga
    52981 tcggttacca cgccagattc gtgttttttc acacggcgaa cttcttctgc ctggcgttca
    53041 atggacatgt ttttgtggat aaagccgata ccgccttcct gagccagagc aatagccagg
    53101 cgcgcttccg ttacggtatc cattgctgcg gaaagcatag ggatattcag acgaatagtt
    53161 ttcgtcagct gagtgctgag gtcagcagta tttggcagaa cggtagaatg agcaggaacg
    53221 aggagaacgt cgtcaaacgt cagagcttct ttagcgatac gtagcatggg caatatctcg
    53281 accagagtgg ttaataaata ttgccgcggc attatacaga gcgtaaccga ttgcatctac
    53341 ccctttttgc aaaaaatgct tgctatcccc ggagggcggg ttactatcga ctgaataacc
    53401 tgctgattta gaatttgatc tcgctcacat gttaccttct caatcccctg caatttttac
    53461 cgttagccgc ctgaatcaaa cggttcgtct gctgcttgag catgagatgg ggcaggtgtg
    53521 gatcagcggc gaaatctcta attttacaca accagcctcc ggtcactggt actttacgct
    53581 taaagacgat accgcgcagg tgcgctgtgc gatgttccgc aacagcaacc gccgggtcac
    53641 cttccaccca cagcacgggc aacaggtttt agttcgcgcc aatattacac tctacgagcc
    53701 gcgcggcgat tatcaaatta tcgtcgaaag tatgcagccg gccggtgagg gattgctgca
    53761 acagaagtac gaacagctta aagcgaagtt gcaggctgaa ggtttgttcg atctgcaata
    53821 caaaaaatca ctcccctccc ctgcgcattg cgttggtgtg atcacctcaa aaaccggtgc
    53881 tacactacat gatattttgc atgtgttaaa acgtcgcgat ccttctctgc cggtgatcat
    53941 ctaccccacc gccgtacagg gggatgatgc gccggggcaa atcgttcgtg ccattgaact
    54001 ggcgaataag cgcaacgagt gtgacgtgtt gatcgttggc cgtggcggcg gttcgctgga
    54061 agatttatgg agctttaacg acgaacgcgt ggcgcgggcg atttttgcca gtcgcattcc
    54121 gatagtcagc gccgtcgggc atgaaaccga tgtgacgatt gccgactttg ttgctgatct
    54181 gcgtgcgcca acgccgtcag ccgccgctga agtggtgagc cgaaatcagc aagaattgct
    54241 acgtcaggtg caatctgccc gtcaacggct ggaaatggcg atggactatt atctcgccaa
    54301 tcgcacgcgg cgctttacgc agatccatca ccgcttgcag caacagcatc cgcagctccg
    54361 gctggcacgc cagcaaacta tgctcgaacg tctgcaaaag cggatgagct ttgcgctgga
    54421 gaatcagctt aaacgcgcgg gtcagcaaca gcagcgatta acacggcaac tcgtccacca
    54481 aaatccgcag tcgcgtattc atcgcgcgca aacgcgcatt cagcaactgg aatatcgttt
    54541 agcagaaacc ctgcgcgcac agcttagcgc cacgcgcgaa cggtttggta acgcggtaac
    54601 acacctcgaa gcggttagcc cgctgtcaac gctggcgcgc ggttatagcg tcaccagcgc
    54661 cgccgatggc gcagtgttga agcaggtgaa gcaggtgaaa gtgggcgata cgttgaccac
    54721 gcgactggga gatggcgtgg tcgtcagtga agtgagtgcg gtgacgaaaa cccgcaagcc
    54781 gcgtaaaaaa acctgatagc ccgttgcgta tcaggctttc ggaacctcat attgataggg
    54841 tgggcaaggt tattggaaac aggttgcaaa ccccggcgtt ttcgcaggct gaatgccaca
    54901 gttgagactg ccagagcctt cctcaacacc acaatagaac gatccagcct tatcagtaga
    54961 taaatacggg aagcttatcg atgacggcca tcccaatgtg ctaaagccgg agtgtaatgt
    55021 ttgtaattcg gcactgctcg gcacgttatt catactaccg cactgccgtg cgacatccca
    55081 tttagtggaa tctataacat gtgccagcgc ccaggtttca ttattcacat tgggcgttgc
    55141 tgctgcggta acccctgacg gcaactccga ttttaatagc gggcgatgca gcatcttgcc
    55201 acttaccgtg gcggtatccg ccatatgacc ccagaaatac gccgtggcga cattaggact
    55261 ggtcggcacg gtgaaaatcg tgtccagcgt cgccgttatt gtggcgttat ccgtcagcgt
    55321 caccgtcaac ggcgttttat atcctggcgt attatcctga ccaacggtaa aacttgctgt
    55381 accgtctgct ccagtaactc catcgattgt attcccgcta tcagccaacg tgactgccgc
    55441 accggatgag ggttgtacag tcaaatcgtc cattgtatcc acatcgccat acaacgtcgc
    55501 cccgctatta cgcggcgtag cgtcaccacg tttgaggata aacgaaatat tcggcactgg
    55561 tttcccgaca ctgtctttca cggtaacgac aacgggaacg gcgtcgcctt ttttcacctt
    55621 cgccgcctgc gtactgctat ccagtgccgt cgatgtcaac gtgacgctgg agacagtcgc
    55681 acgcgggtta accaggcacc cttgatacgc ggtattcacc gtcccccacg ctgaaccatt
    55741 attcagaccg actacctgcg gattactgcc tcccagccag ttatccagcg cccaccatgt
    55801 atactgcgta gaccaaccga tttgtgtcgt cagcgtgttc cccggatagc gagcatagag
    55861 cgattctaaa tcatcactca atggccgacg tgccgcttca caagggctga gattgctgtc
    55921 agccctctgc gttgcgttaa acacgggcca gacttcattg ttactattga ccttgctaac
    55981 ccctgatgtc gacggcagct ctttccacaa tttaggtctt tcaaagacca caccgttttc
    56041 tgccgttacc gtatccggca tatgacccca gtaggccgcc attgcggaat cagggctggt
    56101 gacaacggtg aagatcgcat caaggacagt ggtggtttcc gtatcacgtg ccaggatggc
    56161 ggtaaacggt gttgccaggc cgacagtatc aggctgttca acattgaata tcgccgtacc
    56221 atcgctgccg gtaaaaccaa gccattgcgt gccgtgtgag gcgagagtga atgttgccga
    56281 cacgggtgcc agttccgtca ataccatcac atttgctgcc gtgtttacaa tggttcctga
    56341 gcggctcatc gcattatcac gcctgagcgt tatcgcttcg cccgccagcg ggttgccatc
    56401 acgatctttg accataacca caattggcaa tgggttatct tttttcactg acgcgctagg
    56461 tcggccgcca ttgctgaggg ttctggcgtc atccagtgcg gatgacgtca atgttacgct
    56521 aacgcctgcc ggatgcggct gcgccagaca gagcatcagt gcgttggttg cagaattctt
    56581 cgcgatagct cctgttctca ggctgacagt ctgataagac cacgttgttg tacccagtat
    56641 ggccatatca taagcccacc agttacccgc attcatcggt aacccaaggt cagtcattat
    56701 tgcgccgttc ggatgatcac tatacaaatc caacagttcc ttactgcgcg gttgattctc
    56761 gagtgggcaa tctgtagatg ttaaattttg caagttgctc atatacgacc aaacttcgcc
    56821 gttagaacta atcgataagc ctgagctggt ttcggttttc agcaggggtc gtttgaaggt
    56881 gacgcccgcc gaactggtaa aggtgtccgg catatgcccc cagaatttag cactcggtga
    56941 atctgggctg gtaatcaccg tgtagataac atccagcgtg gcgactttcg ttgtatcacg
    57001 cgccagcgtc acggttaacg gcgtcgccaa cccggtagta gagtactgcc caacctcaaa
    57061 ggtggctgtg ccatcactgc ccgtcgttgc gagagttttt gctccacttg ctgtcaacac
    57121 gctatcccta ctcaccggaa ccaatgccgt tacggtaaga tcgtctgcac tcgtgttaac
    57181 ggttgctttc gcgcgatcca gcgtcgtttc acgcgaaagg gtaaagtcgg catatggcat
    57241 cgggttcccg gcgctatcac gcacggtcac cgtcaacgga atcagctcac ctttcttcgc
    57301 tacagcgctc ggtcgtccat cattgctgag cgattttgct gcatcctgcg ccgttgaggt
    57361 aagctctatt gtgactgctt ccgtatgagg ctctaccaaa cacatcacta tcgccgtata
    57421 gctggacgat gcctgaatca actgaccatt tcccggaaca aacgcctggt tactccagct
    57481 accgcccgct accgccatca tgtcataatc ccaccagttc cctgcagcag tcggcaagcc
    57541 gagcaccgtt gccagttgac cattgggata atcgacatac agcccctgca tatcagtcgt
    57601 cagcggttga tacgcctcat cacacccagc cttgctgacg tccgctttct cagtcgcggt
    57661 caggagcgac cagacttcat tattggccgt tttcgccgta ccgccagaga gttcggcttt
    57721 gaggaaaggc cgtttgaagg tgacgccttc gctgctggta aaggtttccg ccatatggcc
    57781 ccaattggtc gccagcggcg tatccgggct ggtggtgacg gtaaagatca ccgacaaggt
    57841 gtccgacgac acgccagtat cgtttaatag agcataaaag tcggttctta acccagtgga
    57901 agcatcctgt cggagcgtca tcgtagtggt tccatctggc cctgttacac catacaggat
    57961 ggtcgttgca ctggtatcca ccgtcgcacc cgccgcagtc gtgactgaca ctttctgcga
    58021 tgacgtcaca ttctgacgat tgatcgagtt cgcgtgtttc agggcaaacg gcgtattgcc
    58081 gactaaattc ccctgcgcat ctttagtcga aatgcggatc gacacctcat cccccttctt
    58141 cgctttgacg gcgctaagtg tgctgtcaat gctgacaaac tgcccggggt ctgaggcttc
    58201 cagcgtaatc tggctggcag tcatcaacgg cgttgtacgg caggtttgta acgccagcac
    58261 ggtggatacg atttgcgaaa ctgcgccaga atttagttgc accacattgt agtaacggct
    58321 ccctgtttgt gtattactcg gggtattggt gagataactc atatttaccg gccatccctg
    58381 taccgtattc atcgcattac ctctattggc gtcatacaaa gacttcagac catccagcgt
    58441 tggcatataa tctgtaccac acccattcat gctggtgtca gccgactgag tcgaggtgaa
    58501 tcttgcccaa ctttcaccgt tctcaaacgt gctatatcgt gcatagttgt tggtaagctc
    58561 gccaaacagc aacggtcgct tataaaccga accatcggag gccgtcaccg tttcggccat
    58621 atgtccccaa aaattcgctt ttggcgaatc cgggctggtc acgacggtaa agaccaccgg
    58681 tagcatcgcc ttgacgctgc tggacgtatc cagttttgcc gtgagatcgg ttcttaaccc
    58741 ggtactgtta tcctgtttta gggtaaatgt cgttgacccg tcggcaccgg tcacgccgta
    58801 aatggtttca ctcgttgact ggaaattatt tcgcgtattt ccccacgcat ccgtcaccgt
    58861 cagcgcgccc acactcatcg tcgccgatga attagcccga cttacactgt tggctcgcgt
    58921 caggataaat gccgtattgc ccacaaggtt gccttgcgca tctttggtga tgacgcgcac
    58981 cacggattct tcgctttttt tcgcttttac cacgttatag gtggtatcca gcgtcaccgg
    59041 atctgccgct tccagcagga tttggctcac cgcggctatc ggcgcggtct ggcaggtcag
    59101 cagctccagc gtcgttgatg acactgccgc actcgtgcca ttgctgagat ctaccgcctt
    59161 gtagttacgc tgctccatgc tgccgttgtc ggaagtgttg gataaatagc gcgttgccac
    59221 cggccagccc tgcacggttt tcatggtgtt gcccgcatta ttagcaaaca gtgacgtcag
    59281 accggcctga gtcggaatat agttggttcc acagccgctg tacgtcgtgg aaaaacttgc
    59341 ataattaatg ttaaacaacg cccagttttc attgtcttca gacgttgatg ttcgcccagt
    59401 ctgataggcc agttccttca acaacagcgg gcgcttaaat accgtaccgt ccgcagcagt
    59461 caccgtttcc ggcatatgtc cccacatttt tgccaggcgg ctatccgggc tggtcaccac
    59521 cgtaaagatt gtgtcgatgc tggatttttt cgtcgcatca gagtaaagca ttgccgtcag
    59581 cgccgttttg gtgccgtgag tatccgggcg ggtaatattg agaattttgc tgccgtcatt
    59641 gtcggtcatg gcggtataca ccgttgcagt gtcgttcaac gtggtttcat ctgccagccc
    59701 gccattgact accaccggcg caaccagcgc atcgccgctg cccgccacat gtttttcgcc
    59761 gctacgggta tagccatcac cgcgattgag ggtaaatggc atatccgcta acgcgttgcc
    59821 ctgtgcgtct tttaccgtca ctttaacctg tagcgtctcg ccttttttca gcgttgccgc
    59881 gctattcccg gtattccatt gcgctttatc aaccacctcc agcgtaatgc tgctggcagg
    59941 tttgttcgcc gtcttcaggc aactgacgta aaccggcgta tcgccgccaa tagtttgtgc
    60001 gccatcgttc agcgctatcg tgaaaaagtg tggagtttta tctgccggtg agttgctcca
    60061 gtaaggctga cgctgtgttg gccaaccgtg cgccgtttgc accgcgttac cactgttggc
    60121 gttatacagc gcacttagct gggaacgacg tggcaacata ttggtgtcgc agccaccttt
    60181 actggtactg gacgtattgg cctggctcac gcgcgcccag atttcgttat tttcggtcag
    60241 ggttccgtcc gggctggcga cttccgacgc cagtttaggc cgggtaaagg ttgatgaatc
    60301 aacggtgatc gtttcatcca tatggcccca catctgcgcg ccggtaacgt ccgggctggt
    60361 tggggtagta aaaataacgc tgtagttaac ggtattcggc aggtaggaat ttaccggcgt
    60421 tacgctcagc accgttttta gcccgacgcc ctgtggttgc ttaatctcga ccgtcgccac
    60481 gccccgggca tcggttattc ccgcataaac cttcgatgac tgtgatgtgc cgtattgcgt
    60541 gttatccatc gtgattgcac cactgctcgg gtcatcaaac ccgctcacct gccccgctcg
    60601 gttatacccc atacctttgg taatggtgaa tgcagtaaag ggtacaggga tattattgag
    60661 cgagttaatc gtacgcacgg tcatcacaat ggtgtcaccc actttggctt gcgcttgggt
    60721 gccaacagac acatcatgat cggtgctgac ttcaacattc gctaccatct cattacccga
    60781 acaggagagg taattcggct taaagccgga atagctgtcg acgctcccgt tccccagatc
    60841 caccgatgaa tgcgtggctt gctccaccgc gcttaaatag ccctgttgtg cagtgggcca
    60901 gccatattca gtaccaatcg cgttaccggg atgggctgaa aacaggcttt ccagtgagct
    60961 ctggcgcggt atatgaccga cgccgcattc cgcctgcata ctggtgtttt gatcgtagag
    61021 cgcccagtct tcgttatttt cccgcactgt tcccaattca tgctcggttt catccgccag
    61081 caacgggcgt ttatacaaac tgccggactc aataatgccg cgcatatggc cccacatccg
    61141 cgctttgtcg ctgtccgggc tggtgattac ggtaaaaatc acatctttgg catctgtggc
    61201 gttaaaatcg ctgcgcattc ttgccgtgat atgggttttc acccccgcgc cgccgggctg
    61261 gctcagggtg agcgaagcct ggccgttggc gtcggtcatg ccttcatagg tatgtgcgtc
    61321 gacctggcga aaattactgc cgccagcaat ctgtaccgga tgggcttccc aggcagtgtc
    61381 ggtttgattc ttacgattga cgccatcatc cagatgtagc gagaagtagt aatacgccag
    61441 cggttgatcg ttgtttttcg tgtcggtgat ggccagacgc atcgtcgcat cctcgcccac
    61501 cttcgctttc atcgcctgcg ccgtgtcatc atagttttct ggcgtgagga cgattttcgg
    61561 ctcgacgtca ggcgcgggct tatccacgca gctcacgagg aacgtggtgc tgtccggctt
    61621 ctgcgtttcg ccacggttag agacatctgc cgcatggtgc tgcccggtaa gccccgccag
    61681 cgatgaccag taataatcgc cctgcatcgg ccagccgagc acagtctgta ccgtggaggg
    61741 aatcaccgtc gccagtgcgc cgaagtggcg catgcccggc agcacggtgc aatggctatc
    61801 tgcgccgctc caggtaaagg tggaccaggt ttcattgtga tcgacgaccg tggcattttc
    61861 gttactgact tccgccgcca gttttggtct actgaacgtg taaccatggg cttccaccgt
    61921 ctccgccata tggccccaca tcgtggcctg cgccacgtcc gggctggtga gcacggtaaa
    61981 gatcaccgcc gcctcactgg tttgtgcaat gccggaaatg ccgactacca gcggcgtttt
    62041 aacaccgggg ccgttaggct gggtcaccgt gatggttgcc gtaccgttag catccgatgt
    62101 gccacgatac tcggttaccg tcgtcgttaa ctcggtgcta tccagcacca ccggcgcggt
    62161 attatttacc gcgccctgac ggttttgggc atctttacgc ttgataataa atggaatatt
    62221 acccgcgacg ttaccctgac aatctttggt ggtgacggtc agcgtgatag tgccgccaac
    62281 ggtggttttt gccgcgccga gcgtttcgtt ataaccactg gcgctcaccg aaattaaatc
    62341 gccctgcgcg ggcgcgatat tcagcgtcac tttctggtca gccagcacca ccgtcccctc
    62401 atagggataa ccggtcgagg tcagcagata aagcagtgga atggtctgct gcgcatcaat
    62461 ctgtggccag gccaccagcg aacgcccggc cagaccttgc gcgcaaaagc tgcggttggc
    62521 gatgggctgt ggattgagcg gcgtatccgg cgtggcggca tccgcccaca ccagactgac
    62581 ggtcggcggc gtctggtttt cccagcgcag cgcaggtggt gtagaaaact ggtcgccttc
    62641 actgtcctga ggattagcaa ctatcaggtt agcagcgtca tcgtcaacgc taaattcatt
    62701 cggtttagca gaaaacgcca catcatgaga tgcagcagga tcaagctgaa cgcttccctg
    62761 ataaacgggt acgctggcgc tatcggcaat aggaactgta ccgttaaact cgcctgtaga
    62821 accaggatat gtctgccatt ccacctctgc ccgtgcaaag tcagacagca taaaggctgc
    62881 caacatgccc agaagcacaa tgatttttcc tggtttcaga cataccgaca tgtagaaaac
    62941 tccagcatga taaacaaaac gtcaacccgt tttgcttaac gcgtcgctaa gcaaaacagg
    63001 cggaaaacag cattcccata cgggaatgct gttgtgcgca ttagtggtgt ttgtaaatga
    63061 tagacagcgt atagccctga acgccgtcgc cgtttgccgg gattgcaagg ccggtcttac
    63121 cattacggtc actaccgtta aggctggttc ttgcttgttc gttagtttgc ggaataacaa
    63181 tgtcattgtt atcgaagctg gcgttggcaa taccgcccgc cgccgcaagt tgtttactgt
    63241 taccgttaaa gacccacgca aagtcgtagt tagcggtaac gtccacatcc gtacccgcgt
    63301 cgtatttacc gttctggttt tcatccgagt acagtttggc cacatacgtt ttgttaagcg
    63361 caatggctgt attaccaccg ataaggttgg tactggtgtc tttctcgaag atggcaactt
    63421 tcaggttctg gttaacaacc ggaccaggat cgacattatc cgtatcgctg ccgccaccgc
    63481 tggccgtaga aatatccagc agagtcagcg aagttccctg gaagggatta ccggtctgag
    63541 tgataggctg gatttcaaca ccgatatagc gtccacgatc gccatcggtg attttataac
    63601 tggtttttcc tgccgccgca gtcaactccg ttttaccgcc acccgcatta tcactgtagc
    63661 tgtaccattt gatggtcgcc gtcgttttcg catcaatgcc tgcggaacca tcatcgatat
    63721 ccccttcggt atcgccgata tcccaaccca gcgtgatggt atcccctgag taaaggcgtt
    63781 tatcagactc gctacctgca ggacggatac ctttactatc agatgtcact ttgatgtgat
    63841 ccgcatcttc cgagttaatc gtagcattcc ccccttcgcg atagagccag ggtatggtcc
    63901 cctcgaattc agctgtcgtt ccactggcga cccaggcagc atcttccgcc atagcgactg
    63961 gtacggcaca gtatccagcc agcatcagtg ccagcgcgac ttttgtcagg ccacgtttca
    64021 tatgaggttt cataaacact ctccttggtt aacattcagc ggtggcccga tcagccatgg
    64081 cgctgttcct atgtcttgct gtaattgacc tgcaaaccgt acccttgcac accatcggtt
    64141 acctgggcac taaacttcgc tgccgcttcc ttgttcgttg ccgggatctc gatatcgacg
    64201 ttagtggtat tggcttgcgc gccagtattg ccatttacgc tatgccccgt gaattcccat
    64261 tggtagtcat actgtttcat ctcttcgtca gtgagctttt cagatagctg gaacacaccg
    64321 tctttgttag cgtcgcgcca caacacaaag cgatatcggc tattgagggg caacggttct
    64381 ttattgccga taagattcac ggatttagcc gcaccaacgc gatagataaa ggcattcagc
    64441 ccgccgatgt cagcccccag gaacgttacg tcaacatagt tactgtcatc atagggggca
    64501 gctttcgcct tccaacggaa ggtgccaggc aacgtactgg agagcgtaac ggtccccttt
    64561 tctttatctt gtttggcgat aaagacacag ggagtctcgg tagtgcaggg gttattcgtc
    64621 agcgtcactt ttttatcgtt ggcatcaaac agctgcgggt tgagattatc ctgcggcaag
    64681 acattaccgt tgcggtcagt gttgtcgcca aagctatcag taatatcgag atccatcacc
    64741 acaccatcta caccatcagc ctgtgcactg gcttcgtggc tgtggttgtt ctcttccggc
    64801 acgttcgcga tgttattaac aatcagctca attttacggt cctgctgaac ggtgatttcc
    64861 accacgcctg agttctgtcg gttgcccttt tcatctttca gcgccaggcg aacccgccag
    64921 gtattgagtt ttccttgttc ggctttgtca gagctgtact gccagacggg cagcaccagg
    64981 ttccagtggt tattgttgcc ctctgtcagg gtattctctt tgataaccgg catcaccagc
    65041 gtgcgggcgg cattgttttt cgcctgccat gacgcagcga caattttgta gtggtggttg
    65101 acaagcgcgt taatggtcca tttacatttt tccagcccga tagcttcttc tggcgtatct
    65161 ttaatcacgc actcgggatg ttcattcatc gcatcagctt tcagccacaa agtgacatcg
    65221 aggggatctt tctctttata ttccagaaca ataaagttgt tacgttcaac aaagtcgtga
    65281 cggctgccca tgagtgagtg agccgcgctc actttgtcag gatcaagctg gtctttgagc
    65341 gggacgccaa actggtagtt aagcgttgcg ttgaccgtgg tatcggtgtt atcaccggtt
    65401 cctgctttga agtccgttcc tacagcaatg agcggaacag gctggtattt cacgcctaac
    65461 gtgacagcga agggatcttt ctctagattg tcggtaccaa atagcgcaac ttcatccccg
    65521 taataatgtt cgaaaacgat tttaccgcca agctgcggat aagcgggaag ccaggcttcg
    65581 gcacgaatat cccaaccgct cgcagggcgt tcttcataaa agtcgaaatc ttcagagtct
    65641 ttccagtcag aaagcggatg ataatagtta ccagaaaatt ttaaataatc agtccacgct
    65701 tcagcgccta tacctaaacg gcgatgtcca cgggtaaaat cataatcata aaatatattt
    65761 ccacccaata accatttatc aaaattatgt cttacaccaa gccctatatt tccgatcgta
    65821 cgatcttctt ttcgttgcgc agaaaattgg ctgaaataaa cagtggtttg attatcgtac
    65881 cagggaacaa aataatcgat ggaactgcca tccagatcgc cgccctgacc aatggagagg
    65941 ttcgaacgga ccttaccgta gggagagagt gtgtcttcaa tataagattg tgcggttgag
    66001 gtgatttgac tttgcagata gcttctggcc tgagattcca gcgcctcagg ggtcaagttt
    66061 tcaaaccctt gcgtggcgga gttgatgacg taatcggctc cgcgctcttt cagcgattta
    66121 cccttgttgg tttgttcatc ctgttgtgct gcctggctac ctaaatcagg taacgattcg
    66181 ttttgcttaa catttatctc tggtgccgcg aaagcagcac cagagataaa tgttagcata
    66241 atacagcgtt tccatcgcag catgtgcttt ccctgtgacg ataaagtcaa aaataatttt
    66301 taatat
//
LOCUS       DAPOXO010000016        62497 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPOXO010000016 DAPOXO010000000
VERSION     DAPOXO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 62497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62497
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.016"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(756..881)
                     /locus_tag="ROH59_001322"
                     /pseudo
     CDS             complement(756..881)
                     /locus_tag="ROH59_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
     gene            923..1153
                     /locus_tag="ROH59_001323"
                     /pseudo
     CDS             923..1153
                     /locus_tag="ROH59_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309956.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            1205..2140
                     /gene="ttcA"
                     /locus_tag="ROH59_001324"
     CDS             1205..2140
                     /gene="ttcA"
                     /locus_tag="ROH59_001324"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDX4803834.1"
                     /translation="MQENQQITKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLETLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK"
     gene            complement(2268..3641)
                     /gene="dbpA"
                     /locus_tag="ROH59_001325"
     CDS             complement(2268..3641)
                     /gene="dbpA"
                     /locus_tag="ROH59_001325"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HDX4803835.1"
                     /translation="MTAFSTLNVLPPAQLTNLNGLGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQSVCDALNEVGQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVPLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(4119..5102)
                     /gene="zntB"
                     /locus_tag="ROH59_001326"
     CDS             complement(4119..5102)
                     /gene="zntB"
                     /locus_tag="ROH59_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HDX4803836.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
     gene            5357..6589
                     /gene="dgcM"
                     /locus_tag="ROH59_001327"
     CDS             5357..6589
                     /gene="dgcM"
                     /locus_tag="ROH59_001327"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HDX4803837.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSEARLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRNEEETALSCRLVLRELTETEPVI
                     IFEGIEAPATLGLKASRSTNYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(6610..7173)
                     /gene="smrA"
                     /locus_tag="ROH59_001328"
     CDS             complement(6610..7173)
                     /gene="smrA"
                     /locus_tag="ROH59_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HDX4803838.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLSRPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMM
                     FSFIQQALADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(7368..8882)
                     /locus_tag="ROH59_001329"
     CDS             complement(7368..8882)
                     /locus_tag="ROH59_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="HDX4803839.1"
                     /translation="MMSMRKHIAFASMCMGLFIAQLDIQIVSSSLNEIGGGLSAGKDE
                     MAWLQTSYLIAEIIVIPLSGWLSRVFSTRWLFTLSAGIFTLMSIACGLAWNIQIMIFF
                     RALQGAAGASMIPLVFTTAFIYYQGKELGLAAAVVSALASLSPTLGPTLGGWITDNLD
                     WRWLFYINILPGIYLVLSIPFLVNFDKPDLSLLKVADYPSIILLAMTLGCLEYTLEEG
                     ARWGWLDDNTIFLTSVLALVSFILFAARTLTISNPIMDLHAFKDKNFTLGCFFSFSGG
                     VGIFSTVYLIPVFLGRVRGLNAEEIGFAVCTTGIFQLFSVPFYFWLSKKINLRWLLMA
                     GLGGFVFSMYLFTPITHEWGWQELLFPQAIRGISQQFAMAPIVTLTLGGIPKERLKLA
                     SGVFNLTRNLGGAIGIALCGSILNNRTNFHFSRMGEKMVSVPHTVNDFISRSALFFNR
                     GGSDQTSEILASTKLLSQLMLREAQTMAFSDTFLLISGLLFIAFLLVPAMNKSS"
     gene            complement(8879..9907)
                     /locus_tag="ROH59_001330"
     CDS             complement(8879..9907)
                     /locus_tag="ROH59_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX4803840.1"
                     /translation="MIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGG
                     NITTVTSKVSGYISAIEVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLES
                     IQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQ
                     QVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQAALTQALLDLEYTLVRAPID
                     GIVANRSAHTGSWVEGGTSLVSLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKG
                     EVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLS
                     VTVSVDER"
     gene            10004..10819
                     /locus_tag="ROH59_001331"
     CDS             10004..10819
                     /locus_tag="ROH59_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707689.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4803841.1"
                     /translation="MTITLQPKASPGHHIIGLDSEHLNGGTVPWHKHLYAQLLYPAEG
                     VVRVWAGESVWLVHASSALWLPPQMPHKFVATGNVLLKTVLVSEAESETLGKVCFMTG
                     ISPLLRELLIAINQLPPSQSTTDKQQLRFSALETLILQEIKMGVKMSLELPWPNDERL
                     QQLCENLLNNQGYLPTLDNLADKINVSSRTLMRLFVKETGLTFRHWVQQMHVISAVTL
                     LDDGYSLTKIAHRLGYASAESFGNMFKRRTGYSPGKFTRRLTMHDYAITRQMI"
     gene            11208..11351
                     /locus_tag="ROH59_001332"
                     /pseudo
     CDS             11208..11351
                     /locus_tag="ROH59_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
     gene            11362..11877
                     /gene="ogt"
                     /locus_tag="ROH59_001333"
     CDS             11362..11877
                     /gene="ogt"
                     /locus_tag="ROH59_001333"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDX4803842.1"
                     /translation="MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            12072..12824
                     /gene="fnr"
                     /locus_tag="ROH59_001334"
     CDS             12072..12824
                     /gene="fnr"
                     /locus_tag="ROH59_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HDX4803843.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            12976..13926
                     /gene="uspE"
                     /locus_tag="ROH59_001335"
     CDS             12976..13926
                     /gene="uspE"
                     /locus_tag="ROH59_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HDX4803844.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(13976..14233)
                     /locus_tag="ROH59_001336"
     CDS             complement(13976..14233)
                     /locus_tag="ROH59_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HDX4803845.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            14477..15508
                     /gene="ynaI"
                     /locus_tag="ROH59_001337"
     CDS             14477..15508
                     /gene="ynaI"
                     /locus_tag="ROH59_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HDX4803846.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFE
                     KQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
                     KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKIKTFDNRPLYVPN
                     SLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLV
                     YFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMD
                     NITPADQGR"
     gene            complement(15559..17172)
                     /gene="mppA"
                     /locus_tag="ROH59_001338"
     CDS             complement(15559..17172)
                     /gene="mppA"
                     /locus_tag="ROH59_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide ABC transporter
                     substrate-binding protein MppA"
                     /protein_id="HDX4803847.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESSKEWTKPGNLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
     gene            complement(17509..18408)
                     /gene="pgrR"
                     /locus_tag="ROH59_001339"
     CDS             complement(17509..18408)
                     /gene="pgrR"
                     /locus_tag="ROH59_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator PgrR"
                     /protein_id="HDX4803848.1"
                     /translation="MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEE
                     RLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDSALTSLSDLQNRPSGTIRITTVE
                     HAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
                     GPDIPMAIVGSPDYFSRRSAPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVR
                     MEGQLLLNTIDLIIDAAIDGHGLAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYY
                     PHRRHAGSAFSLFIDRLKYKGAV"
     gene            18546..19466
                     /locus_tag="ROH59_001340"
     CDS             18546..19466
                     /locus_tag="ROH59_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4803849.1"
                     /translation="MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYPAIVVSHPGG
                     GVKEQTAGTYAEKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDVSAVIDYLTT
                     LSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSMFRNGWENNVKSID
                     ALPYVDAGSNARTSDISSGEYATMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPG
                     YATLRSLNQIITYDAYHMAEVYLTQPIQIVAGSLAGSKWMSDDLYDRASSQDKRYHIV
                     EGANHMDLYDGKVYVAEVISVLAPFFEETL"
     gene            19537..20175
                     /locus_tag="ROH59_001341"
     CDS             19537..20175
                     /locus_tag="ROH59_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707232.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4803850.1"
                     /translation="MKNVLILGAGGQIARHVINQLADKQTIKQTLFARQPAKIHKPYP
                     TNSKIIMGDVLNHAALKQAMQGQDVVYANLTGEDLDIQANSVIAAMKACDVKRLIFVL
                     SLGIYDEVPGKFGEWNNAVIGEPLKPFRRAADAIEASGLEYTILRPAWLTDEDIIDYE
                     LTSRNEPFKGTIVSRKSVAALITDIIDKPEKHIGENIGINQPGTDGDKPFFM"
     gene            20466..21194
                     /gene="mpaA"
                     /locus_tag="ROH59_001342"
     CDS             20466..21194
                     /gene="mpaA"
                     /locus_tag="ROH59_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HDX4803851.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASHESGLI
                     LAGTHGDENSSIVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPS"
     gene            complement(21169..22134)
                     /gene="ycjG"
                     /locus_tag="ROH59_001343"
     CDS             complement(21169..22134)
                     /gene="ycjG"
                     /locus_tag="ROH59_001343"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HDX4803852.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGE
                     CTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARK
                     QQQSLADLIGITLPETVTTAQTIVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFRLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            22253..22759
                     /gene="tpx"
                     /locus_tag="ROH59_001344"
     CDS             22253..22759
                     /gene="tpx"
                     /locus_tag="ROH59_001344"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HDX4803853.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            complement(22803..24344)
                     /gene="tyrR"
                     /locus_tag="ROH59_001345"
     CDS             complement(22803..24344)
                     /gene="tyrR"
                     /locus_tag="ROH59_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HDX4803854.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRASKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGVFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWTGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(24492..25553)
                     /locus_tag="ROH59_001346"
     CDS             complement(24492..25553)
                     /locus_tag="ROH59_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HDX4803855.1"
                     /translation="MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDE
                     AQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            complement(25550..26947)
                     /locus_tag="ROH59_001347"
     CDS             complement(25550..26947)
                     /locus_tag="ROH59_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HDX4803856.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSAKWRMMCEGLDPLAPADENRLADIAAAWTEYLHHCKQQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDAWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGMIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            27103..28101
                     /locus_tag="ROH59_001348"
     CDS             27103..28101
                     /locus_tag="ROH59_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX4803857.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYEIPVVVIGKVEGQYSHV
                     YSVDTDNYGDSIALTNALIESGHKNIACLHAPLDVQVSVDRVNGYKQSLATHNIAVRD
                     EWIVDGGYTHETALKAARELLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDVPTQELGQQSCELLFQLIAGKPSPQNITVATHMSLK"
     gene            complement(28152..29057)
                     /gene="ompG"
                     /locus_tag="ROH59_001349"
     CDS             complement(28152..29057)
                     /gene="ompG"
                     /locus_tag="ROH59_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HDX4803858.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEEKNNWHFNIGAMYEIENVEGYV
                     EDMDGLAEPSVYFNAANGPWRISLAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLESD
                     DFSLGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(29102..30184)
                     /locus_tag="ROH59_001350"
     CDS             complement(29102..30184)
                     /locus_tag="ROH59_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4803859.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFSLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGELLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     IQKIAKEMIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVAGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIC"
     gene            complement(30198..30857)
                     /gene="pgmB"
                     /locus_tag="ROH59_001351"
     CDS             complement(30198..30857)
                     /gene="pgmB"
                     /locus_tag="ROH59_001351"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDX4803860.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNEFL
                     KGISRDESLRRILQHGGKEGDFNPQERAQLAYRKNLLYVHSLRELTVNAVLPGIHNLL
                     VDLRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQN
                     V"
     gene            complement(30854..33121)
                     /gene="ycjT"
                     /locus_tag="ROH59_001352"
     CDS             complement(30854..33121)
                     /gene="ycjT"
                     /locus_tag="ROH59_001352"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HDX4803861.1"
                     /translation="MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKGEINELVNLPDVVGMEIAINGEIFSLSREAWQRELNFASGELR
                     RNVVWRTSNGTGYTIASRRFVSADQLPLIALEITITPLDADASVLISTGIDATQTNHG
                     RQHIDEIQVRVFGQHLMQGIYTTQDGRSDVAISCCCKVSGDVQQCYTAKERRLLQHTC
                     AQLHAGETLTLQKLVWIDWRDDRQAALDEWGSASLRQLEMCAQQSYDQLLAASTENWR
                     QWWQKRRITVNGRDAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSDPTVARSLLRYRWHNLPGAQEKARRNGWQGALFPWESARSGEEETP
                     EFAAINIRTGLRQKVASAQAEHHLVADIAWAVIQYWRTTGDESFIAHEGMALLLETAK
                     FWISRAVRVNERLEIHDVIGPDEYTEHVNNNAFTSYMAYYNVQQALNIARQFGCSDDA
                     FIHRAEMYLKELRLPEIQPDGVLPQDDSFMAKPVINLAKYKAAAGKQTILLDYSRAEV
                     NEMQILKQADVVMLNYMLPEQFSAASCLANLQFYEPRTIHDSSLSKAIHGIVAARCGL
                     LTQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQGFAGVSVRDGELHLNPA
                     LPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNGQLIYVAEESVFCLGDF
                     ILPFNGTATTHQEGE"
     gene            complement(33118..34173)
                     /locus_tag="ROH59_001353"
     CDS             complement(33118..34173)
                     /locus_tag="ROH59_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDX4803862.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALAEKYGNASLWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTAEQAREMCDTARKQGKVLAYDFHHRFAFDTQQLREQVTNGVLGEIYVTTARA
                     LRRSGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQREMADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(34183..34971)
                     /locus_tag="ROH59_001354"
     CDS             complement(34183..34971)
                     /locus_tag="ROH59_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDX4803863.1"
                     /translation="MKIGTQNQAFFPGNILEKFRYIKEMGFDGFEIDGKLLVNNIEEV
                     KAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENDLKHVQIIGDFYHMNIEEDNLAQALHDHRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEAPAQAYRDSLAWLRTC"
     gene            complement(34989..36041)
                     /locus_tag="ROH59_001355"
     CDS             complement(34989..36041)
                     /locus_tag="ROH59_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDX4803864.1"
                     /translation="MKKLVATAPRVAALVEYEERAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFSPRPANAPRGIEFGKFQLGNMVVGDIIECGSDVNDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGADVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(36072..36914)
                     /locus_tag="ROH59_001356"
     CDS             complement(36072..36914)
                     /locus_tag="ROH59_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDX4803865.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKSAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPVIFPFVDYFRNSMVVSVVSSVVAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(36901..37782)
                     /locus_tag="ROH59_001357"
     CDS             complement(36901..37782)
                     /locus_tag="ROH59_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDX4803866.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     RLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(37803..39095)
                     /locus_tag="ROH59_001358"
     CDS             complement(37803..39095)
                     /locus_tag="ROH59_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4803867.1"
                     /translation="MIKSKIVLLSALVSCALISGCKEENKNNVSIEFMHSSVEQERQA
                     VISKLIARFEKENPGITVKQVPVEEDAYNTKVITLSRSGSLPEVIETSHDYAKVMDKE
                     QLIDRKAVATVISNVGEGAFYDGVLRIVRTEDGSAWTGVPVSAWIGGIWYRKDVLAKA
                     GLEEPKNWQQLLDVAQKLNDPANKKYGIALPTAESVLTEQSFSQFALSNQANVFNAEG
                     KITLDTPEMMQALTYYRNLAANTMPGSNDIMEVKDAFMNGTAPMAIYSTYILPAVIKE
                     GDPKNVGFVVPTEKNSAVYGMLTSLTITAGQKTEETEAAEKFVTFMEQADNIADWVMM
                     SPGAALPVNKAVVTTATWKDNDVIKALGELPNQLISELPNIQVFGAVGDKNFTRMGDV
                     TGSGVVSSMVHNVTVGKADLPGTLQASQKKLDELVEQR"
     gene            complement(39109..40788)
                     /gene="ycjM"
                     /locus_tag="ROH59_001359"
     CDS             complement(39109..40788)
                     /gene="ycjM"
                     /locus_tag="ROH59_001359"
                     /EC_number="2.4.1.352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosylglycerate phosphorylase"
                     /protein_id="HDX4803868.1"
                     /translation="MQQKITDYLDEIYGGTFTATHLQKLVTRLESAKRLITQRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYPQWLQRIFSHVHLLPFYPWSSDDGFSVID
                     YHQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQQPGFEDFFITVDP
                     KTDLSAVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LEKGAEYVRLDAVGFMWKEPGTNCIHLEKTHLIIKLLRSIIDNVAPGTVIITETNVPH
                     KDNIAYFGEGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPENEILALVEVLQQEGALVNWKNNPDGTRSPYEMNVTYMDALS
                     RRECSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLGYNRAINRKKY
                     SSKEITTELDNKATLRYSVYYKLSHLITLRRSHKEFHPDNNFTIDAINSFVMRIQRSN
                     ADGDCLTGLFNVSENIQHINITDLHGRDLISEVDILGNEITLHPWQVMWIK"
     gene            complement(40999..41313)
                     /gene="pspE"
                     /locus_tag="ROH59_001360"
     CDS             complement(40999..41313)
                     /gene="pspE"
                     /locus_tag="ROH59_001360"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HDX4803869.1"
                     /translation="MFKKGLLALTLVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(41388..41609)
                     /gene="pspD"
                     /locus_tag="ROH59_001361"
     CDS             complement(41388..41609)
                     /gene="pspD"
                     /locus_tag="ROH59_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HDX4803870.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(41618..41977)
                     /gene="pspC"
                     /locus_tag="ROH59_001362"
     CDS             complement(41618..41977)
                     /gene="pspC"
                     /locus_tag="ROH59_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HDX4803871.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(41977..42201)
                     /gene="pspB"
                     /locus_tag="ROH59_001363"
     CDS             complement(41977..42201)
                     /gene="pspB"
                     /locus_tag="ROH59_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HDX4803872.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(42255..42923)
                     /gene="pspA"
                     /locus_tag="ROH59_001364"
     CDS             complement(42255..42923)
                     /gene="pspA"
                     /locus_tag="ROH59_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HDX4803873.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREIEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLVRMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            43090..44067
                     /gene="pspF"
                     /locus_tag="ROH59_001365"
     CDS             43090..44067
                     /gene="pspF"
                     /locus_tag="ROH59_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HDX4803874.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEHFAIQMCREIKLPLFPGFTEHARETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPSEEAIAVSENTSLPTLP
                     LDLREFQMQQEKELLQVSLEQGKYNQKRAAELLGLTYHQFRALLKKHQL"
     gene            44221..44358
                     /locus_tag="ROH59_001366"
                     /pseudo
     CDS             44221..44358
                     /locus_tag="ROH59_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415812.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Putrescine importer PuuP"
     gene            44492..44737
                     /locus_tag="ROH59_001367"
     CDS             44492..44737
                     /locus_tag="ROH59_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HDX4803875.1"
                     /translation="MNHDIPLKYYDIADEYATECAEPVADAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            45050..46693
                     /gene="sapA"
                     /locus_tag="ROH59_001368"
     CDS             45050..46693
                     /gene="sapA"
                     /locus_tag="ROH59_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HDX4803876.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYAGKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQYIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKALGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            46690..47655
                     /gene="sapB"
                     /locus_tag="ROH59_001369"
     CDS             46690..47655
                     /gene="sapB"
                     /locus_tag="ROH59_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HDX4803877.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMIISAIRHMVLPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            47642..48532
                     /gene="sapC"
                     /locus_tag="ROH59_001370"
     CDS             47642..48532
                     /gene="sapC"
                     /locus_tag="ROH59_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HDX4803878.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            48532..49524
                     /gene="sapD"
                     /locus_tag="ROH59_001371"
     CDS             48532..49524
                     /gene="sapD"
                     /locus_tag="ROH59_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HDX4803879.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            49526..50332
                     /gene="sapF"
                     /locus_tag="ROH59_001372"
     CDS             49526..50332
                     /gene="sapF"
                     /locus_tag="ROH59_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HDX4803880.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            complement(50380..51543)
                     /locus_tag="ROH59_001373"
     CDS             complement(50380..51543)
                     /locus_tag="ROH59_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HDX4803881.1"
                     /translation="MARVSLSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTIT
                     QLTLTASLIGLGVGQLLFGPLSDKIGRKRPLILSLLLFIVSSILCATTNNIYWLVVWR
                     FIQGIAGAGGSVLSRSIARDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDW
                     RTLFWVMAEISTVLLLGCLLFIHETLPENKRGSSLLLTGRSVVQNRRFMRFCLIQSFM
                     LAGLFAYIGSSSFVLQKEFGFSPMQFSLVFGLNGTGLIIASWIFSRLARRINAMTLLR
                     GGLIAAILCALLTVLCAWIQLPIPALVALFFTIAFCSGIGTVGGAEAMSAVGTQESGT
                     ASALMGMSMFVFGGIAAPLSGIGGETLLKMSLAITVCYTLALLVALTRIDNQK"
     gene            complement(51552..52925)
                     /locus_tag="ROH59_001374"
     CDS             complement(51552..52925)
                     /locus_tag="ROH59_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDX4803882.1"
                     /translation="MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQGQGKAI
                     SHDWQQVIHDPRLQQVVTIALNSNRDVQKAIADIDSARALYGQTNASLFPTVNAALSS
                     TRSRSLANGTGTTAEADGTVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIA
                     EISTAWLTLAADNSNLALAKETMASAENSLKIIQRQQQVGTAAATDVSEAMSVYQQAR
                     ASVASYQTQVMQDKNALNLLAGTTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRP
                     DIQEAEHNLKSANADIGAARANFFPTISLTASAGVGSDALSSLFSHGMQIWSFAPSVT
                     LPLFTGGSNLAQLRYAEAQKRGLIATYEKTVQSAFKDVANALARRTTLEEQLDAQRQY
                     VKAEQQTVDVGLRRYQAGVGDYLTVLTAQRSLWSAQQELLALQLTDFTNRITLWQSLG
                     GGMSSLK"
     gene            complement(52929..56036)
                     /locus_tag="ROH59_001375"
     CDS             complement(52929..56036)
                     /locus_tag="ROH59_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HDX4803883.1"
                     /translation="MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTI
                     KISATYTGASAETLENSVTQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPD
                     TAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
                     SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAG
                     KIGALPSPDTQQLTATVRAQSRLQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDY
                     TAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFI
                     KISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSIN
                     TLTLFAMVLAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALVAIALVL
                     SAVFLPMAFFGGSTGVIYRQFSITIISAMLLSVVVALTLTPALCGSVLQHVPPHKKGF
                     FGAFNRFYRRTEDKYQRGVIYVLRRAARTMGLYVVLGGGMALMMWKLPGSFLPTEDQG
                     EIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAF
                     VSLKNWSQRKGAENTAQAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLA
                     NGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMPQLQVDIDSNKAVSLGLSLND
                     VTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSA
                     FATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSG
                     LSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVILVIPLGLLGAALAAWMR
                     DLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALRAAQTRLRPIIMT
                     SLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGK
                     PRRQE"
     gene            complement(56036..57157)
                     /locus_tag="ROH59_001376"
     CDS             complement(56036..57157)
                     /locus_tag="ROH59_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDX4803884.1"
                     /translation="MKYIATSVVAMLLLSGCDNTQSNNSSPSETEVGVVTLKSQPVSV
                     VSELTGRTSAALSAEVRPQVGGIIQKRLFKEGDLVKAGQPLYQIDAASYQAAWNEARA
                     ALQQAQALVKADCQKAQRYARLVKENGVSQQDADDAQSTCAQDKASVEAKKAALETAR
                     INLDWTTVTAPISGRIGISSVTPGALVTASQDTALTTIRGLDTMYVDLTRSSVDLLRL
                     RKQSLATNSDTMSVSLILEDGTTYSEKGRLELTEVAVDESTGSVTLRAIFPNPQQQLL
                     PGMFVRARVDEGVMENAILAPQQGVTRDAKGNATALVVNKDNKVEQRTLETGETYGDK
                     WLVLNGLHNGDRLIVEGSAKVTSGQTVKAVEVQANGGNA"
     gene            complement(57306..57872)
                     /locus_tag="ROH59_001377"
     CDS             complement(57306..57872)
                     /locus_tag="ROH59_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX4803885.1"
                     /translation="MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLS
                     VGQIYRYFANKDAIIEEMVRRIIDFRIAQMDIDARTDHFPEVLALRKSLNEDDDALML
                     EVAAEATRNPRVMAMLEEADARMFANGCAHMKRMHPHLSDEHIRCCVEVFATMMEGTV
                     YRRLTPQKSDPQHLQEIYQDIVSMLINK"
     gene            58350..59138
                     /gene="fabI"
                     /locus_tag="ROH59_001378"
     CDS             58350..59138
                     /gene="fabI"
                     /locus_tag="ROH59_001378"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDX4803886.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDTSIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            59283..60410
                     /locus_tag="ROH59_001379"
     CDS             59283..60410
                     /locus_tag="ROH59_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707196.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HDX4803887.1"
                     /translation="MEQRHITGKSHWYHETQSSTAEYDVLPLVPEAAKVSDPFLLDVI
                     LDEETLAPFLSWLVPARVLAVELFPDPLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSSRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTVCDC
                     VIINQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESLRWRSSYEV
                     EKLPEEHTKSSTAELCQLANTLSLHPISLSLLEKLLNSTRVNTQPDNQLAALLCARIN
                     GSPACFAACMNSSNEYKKISPLLRKGENEINRWADRHSVERATVQAIQWLTRAPDRFS
                     AAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            60478..62412
                     /gene="rnb"
                     /locus_tag="ROH59_001380"
     CDS             60478..62412
                     /gene="rnb"
                     /locus_tag="ROH59_001380"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HDX4803888.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DGKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSTDGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETAYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
BASE COUNT        15808 a        16297 c        14819 g        15573 t
ORIGIN      
        1 tacatagtgc attggcatga ccaaacatca atgccattat actcgcctct gttaaatact
       61 cgctagttaa tatgataggc acgcatgata taacaatcca tatgctaata cataaataca
      121 tcagtatttt tctcatagtc agtccctgtg attaacaatc aaggcatagt taagcatatt
      181 tcacattcaa acgtaaacat tattaataac attatatcaa tcgaactgac atcacgattc
      241 aagccctctt caaactgaag gttagagcag cgtagaacat ttcaaaacaa tacactaaaa
      301 aaatacctga acaaaaaact taattctttt ttattgtgaa ctttagtgat tttgtcatgc
      361 aactctttat tacatttagg cctgtattat ttcatggcaa cgcagataca ggaccatttc
      421 ttgtgctatg gataagtaat aagctagtta catcttatta agagaaccat tttcacatat
      481 caagatatca tcaccaccca caatgaatta agtatttttc ttattcttta gattagatac
      541 gtaatgaatc cctaactcca ttcgggtgtc atggctcttt catttgaaat atattcatat
      601 ccaatgtaat atttccatgc gcaaatataa tcaccaacca tacccatcat ttattacaga
      661 gaattatttt attcaccgaa aggtttcaca aaatatcccc tgatagaaaa ctaaaaaaca
      721 ctgcataata tcgctattct ggcacttgcg aaaaattata ttctgcacct gttgtagcgt
      781 tctatttctc tgcctggcaa cgaatgcaca atgtccgcca cagtttctgt tctaatttct
      841 tcctgtgtta ccgcatcctg tacgggtagc gcaacaccag catgctaagc aaggctttcc
      901 catcagattt cactacgact atttgggagc gagatggaat gcagcagtaa aacgtgctgg
      961 tattcgccgc cgtaatccgt accatacgcg acatactttt gcctgctggc tgttgacggc
     1021 aggagcgaac ccggcattta tagccagcca gatggggcat gaaactgcgc agatggtgta
     1081 tgaaatttac ggtatgtgga ttgatgacat gaacgacgaa caggtagcca tgttgaatgc
     1141 gcggttatcg tagttgcaaa gtttgccctc aatatgcccc atttagtacc agagaactga
     1201 aataatgcaa gaaaatcaac aaattacaaa gaaagaacaa tacaacctga acaaattaca
     1261 aaaacgtctg cgtcgtaacg tgggcgaagc cattgctgac ttcaatatga ttgaagaagg
     1321 cgatcgcatc atggtttgcc tctccggggg taaagacagc tataccatgc tggagattct
     1381 gcgcaatttg cagcaaagcg cgccaatcaa tttttcgctg gtggctgtta acctcgatca
     1441 aaagcaaccg ggcttcccgg aacacgttct gcccgagtat cttgaaacgc tgggcgttga
     1501 gtacaagatt gttgaagaga acacttacgg tatcgtgaaa gagaagattc cggagggcaa
     1561 aaccacttgc tcactgtgtt ctcgtcttcg tcgcggtatc ctttatcgca ccgcaacgga
     1621 actgggggcg acgaagatcg cgctgggtca ccatcgtgac gatatcctgc aaacgctgtt
     1681 cttaaatatg ttctacggtg gcaagatgaa aggtatgcct ccgaaactga tgagcgatga
     1741 tggcaaacat atcgtgattc gtccgctggc ctactgccgc gagaaagata ttcagcgctt
     1801 tgccgatgca aaagcgttcc cgattattcc gtgcaacctg tgcggttcac agcctaacct
     1861 gcaacgtcag gtaattgctg acatgttgcg tgactgggat aaacgttatc cggggcgtat
     1921 cgagacgatg ttcagcgcaa tgcagaatgt ggtgccgtcg catctgtgcg ataccaacct
     1981 gttcgatttc aaaggcatta cccacggttc tgaagtggtt aacggggggg atctggcgtt
     2041 tgatcgcgaa gagatcccac tacaaccagc gggctggcag ccagaagaag atgaaaatca
     2101 gttggatgag ttacggctga atgtggttga agtgaaataa ccaggatagc gcccgatacg
     2161 caagcgtatc gggctactct tatggaagcc gataagacgc ggccagcgtc gcatccggca
     2221 atgccgaaga agatgtttac acttgcaccc tgcaattcaa catttcatta ttttaataac
     2281 cgcacccggc acgtttttcc tttaatcttc ccgccctgta actgtttcca tgctttatga
     2341 gcaacagcct gacgcaccgc gacataaaca tgcgccggat gcacggcaat tttgccaata
     2401 tctgcgccat caagcccgat gtctcctgtc agcgcaccta atacatcacc cgggcgcatt
     2461 ttggcttttt tcccgccatc gatacacaac gttgccattt ctgcttccag cggcacaatg
     2521 gaactattcg ctggcggcgt ttgccagtta agttttatct gcaacatgtc agaaatgata
     2581 ttggcccgct gtgcttcttc cggagcacag aaactgatcg ccagaccgct atttcctgca
     2641 cgagctgtac gaccgatgcg atgtacatga acttcagggt cccacgccag ctcaaagttc
     2701 accaccagct caagcgattt tatatccaga ccacgcgcag caacatcagt cgcgaccagt
     2761 acacgggcgc taccgttagc aaaacgtacc agggtctgat cgcgatcgcg ttgctccaga
     2821 tcgccgtgta acgacaatgc actttgccct acttcattca gcgcgtcgca gacagactgg
     2881 caatcttttt tggtattgca aaacaccacg caagaggatg gctgatgcaa gcttaataac
     2941 cgttgcaaca gaggaatttt gcctttgctg gatgtctcat aaaattgttg ttcaataggt
     3001 ggcagagcat ctgttgagtc aatttcaatc gctaaaggat cgcgctgcac tcttccgctg
     3061 attgcggcaa tggcttccgg ccaggttgcc gaaaacagaa gtgtctgccg agatgctggc
     3121 gcaaaacgga tgacatcatc aatggcgtca ctaaatccca tatccagcat gcggtcggcc
     3181 tcatccatca ccagcgtatt caacgcatcc agtgatacag tgcctttttg caggtgatcc
     3241 agcaaacggc ccggcgttgc cacgataata tgcggcgcat gttgtaacga atcacgctgc
     3301 ataccgaacg gttgaccacc gcacaacgtc aaaattttgg tatttggcag aaaacgcgcc
     3361 agccgacgca attcacctgc cacctgatcc gccagttcac gcgtaggaca cagcactaaa
     3421 gcctgggttt gaaatagcga cgcatcaatt tgctgtaaca agccgaggcc aaaagccgcc
     3481 gttttgccgc tgccggtttt cgcctgcacg cgaacatctt ttccggcaag gatcgccgga
     3541 agcgcggcgg cctgcaccgg cgtcatggtt aaataaccca acccattaag gtttgtgagt
     3601 tgggcgggag gcaaaacatt cagggtagaa aaagcggtca caatctattc tcgtggtcat
     3661 cgacgcaaag tcagcaggcg cgtatcctcg cagatctacg ctcacgatgc gacaatttaa
     3721 tcggctcttc atcgggtggt gggtcaggca tgggttgcgg gcgagggatc ggatcgggca
     3781 cgggaacagg atcgccagga atcggttcag ggacaggaat ttgcaaataa ataagtgtcg
     3841 tcatatttcc ctccggtcat tgggtggact cttaaagggt agacgctgat aaataacagg
     3901 caaaaaaaag ccgactcatc aaagtcggcg tcgtacgaat caattgtgct atgcagtaat
     3961 tcaaaaaagg aagtaagaca atatggagcg caacgcccat cgcttgacgt tgcattcacc
     4021 tgcaagagag atattgccct gaatgggtag agagtttatt gacttcgctc aaactttacg
     4081 gcgtttttgt atacagacag ccgggaaaat tgcttttgtt acaaccattt actacgatgc
     4141 aaccataaag caacaccacc aataagaaca actaacagaa tacaaaaaat tgaaaatccg
     4201 aattgccatc caccgccagg gatcccacca aggttgacgc caaataaccc tgtcagaaac
     4261 gtactgggta aaaagaccat tgccatcaac gacattgtat aagtacgacg agctaaattt
     4321 tcctgcatca cctgagcgat ttcatccgcc atcacgccag tccgtgctat acaggcgtcg
     4381 atttcgtcaa gaccgcgccc aaggcgatcg gcaatatcct gcatccgacg gcgttggtca
     4441 tcgctcatcc acggcaaacg ttcactggca agacgagcat aaacatcacg ttgcggtgcc
     4501 atatagcgac gcatcacaat taattgtttg cgcagcagag ccaggaatcc acgcggtgga
     4561 atttgctgat cgagaagatt atcttcgagg tcgataattt tatcgtgcag ctgctcgata
     4621 aattcgctgg aatgatcggt caacgcatcg cacacatcaa ccagccaccc cccgcaatcg
     4681 gtcggaccag tgccctcttc cagatcgctc accacatcgt ccagcgccag cactttgcgt
     4741 tgtcgggtcg aaacaattaa ccgcccgtcc atatatacac gcatggcgac cagttgatcg
     4801 gggcgttcat cggtgctgcc gtttatacag cgcaatgtaa tcagcgtgcc ttcaccgaga
     4861 cggctgactc ggggccgtgt gctctcgccc gccagcgcat cacgtacgtt attgggaagc
     4921 agcggtgttg tcgccagcca ttgggcgcta tcatggtgta cataattaag gtggagccag
     4981 cagggatgcg cttcatcaat cacatctgta ttttccagcg gtttaacgcc gcctctacca
     5041 tccagcatcc atgcaaatac tgcatccggg acattaacgt ccgatccctt aatcgcttcc
     5101 acagtgcctc catcatcaac gcattatttt gtagtctagc cttctggccc tgttacgcaa
     5161 catctcatca ccccattacc ctgaaatgat taataaaatt ctgtctaaat tgaatacaaa
     5221 aagcaaaatg cttttccgta tacaaaccgt gtgaagtgtt aaatagcgtc tatcattatc
     5281 agaattatct gatcatatga cgtggctttt ttgcgatcgg atagcaacaa caattgataa
     5341 aaataatggg atctcaatga ttacgcacaa cttcaatacc ctggacttac tcaccagtcc
     5401 tgtctggatc gtttcgccct ttgaggaaca gttaatttat gccaacagcg aggcgcgact
     5461 gttgatgcaa gacctcacgt ttagtcagct acgaaccggt ccctattccg tctcctcaca
     5521 aaaagaactg ccgaaatacc tctccgatct gcaaaatcaa cacgatatta tcgaaatcct
     5581 caccgttcag cgcaatgaag aggaaacagc attaagctgt cggcttgttt tgcgagagct
     5641 gacagaaaca gaaccggtga ttattttcga aggtatcgaa gcaccggcaa cgctgggttt
     5701 aaaagccagt cgctcgacaa attatcagcg caaaaaacaa ggtttttatg cgcgcttttt
     5761 tctgactaac tctgcgccaa tgttgttgat tgacccctca cgagatggcc aaatcgttga
     5821 tgctaacctc gccgctctca atttctatgg ttataaccat gaaacgatgt gccagaaaca
     5881 tacctgggaa ataaatatgc tcgggcgtcg cgtcatgcct atcatgcatg aaatctcgca
     5941 tttacccggt ggtcataaac ctttgaattt tgttcataaa ctggcggatg gttcgactcg
     6001 tcatgtgcag acctatgccg ggccgattga aatttatggc gacaagctca tgttatgtat
     6061 tgtgcatgat attactgagc aaaaacggct ggaggagcag ctggaacatg ctgcccacca
     6121 tgatgcgatg acaggattac tgaatcggcg acagttttat cacattaccg agccaggcca
     6181 aatgcagcac ctcgccatcg ctcaggatta cagcttgttg ctcatcgaca ccgatcgttt
     6241 taaacacatt aacgatctct atgggcattc taaaggtgat gaggtgttat gcgcccttgc
     6301 ccgcactctc gaaagttgcg ctcgcaaagg cgatttggtg tttcgttggg gaggcgaaga
     6361 gtttgtctta ttgctaccaa gaaccccact ggataccgcg ctttcgctgg ctgaaactat
     6421 ccgcgtaagc gtggcaaaag tgagtatttc gggcttacca cgctttactg tcagcattgg
     6481 tgtggcgcat cacgaaggaa atgaaagcat cgatgaactg tttaaacgcg ttgatgatgc
     6541 tttgtatcga gcgaaaaatg atggacgcaa ccgcgtgctg gcggcataag ccacggatgc
     6601 gtctcgtgat caacgactgc gcttagcatg gcgctcccag ttttcttgct tcgcctgcgc
     6661 tgttttacgt agtgcgacgt aacacgcccc gctgccgcca tgatgcggta gcgcagtgca
     6721 atatgcctga acatcatcaa attcggtcag ccagcgcgcc acatagctgc ggacaatatt
     6781 ggcatgcgat ttatcatccc gtcctttgcc atgaataatc agcacgttac gcaaaccatc
     6841 cgccagggct tgttgaatga aactgaacat cattttgcgg cactcttcca ccggctggcg
     6901 caaaagattc aggctcgcct gttgcggata tttaccactg cgcagcttat ccagcacccc
     6961 atgttgcaac ccttcccgcc gaaactccag cggccgactt agcgggatga tgtcgagaaa
     7021 tccagtggtg aggaaattat caagttgcag cgtgtcgata cgctgcggcg cacgttggtt
     7081 acgcgttgga tgccagtgga catctgtagc acgtttcagc ggctggacat cttccatggc
     7141 gtcaagaaac agcgatttgt cgtcaaggtt catgtaacct cctatgcacc ttcacacgtc
     7201 gtgattcaga cgggttaatt gttcatactt actgcatcgt tcccttcaca gattgaaaca
     7261 atactctact tcatacctgt gagtatctgc gcaggcggag cattttatac tagcctgtta
     7321 gcagtatcga acagtttagc ccgagtttaa ttcagcacag gctccgatca ggatgattta
     7381 ttcatagcag gaaccaacaa aaatgcgata aataacagac cactgattag cagaaaggta
     7441 tccgaaaatg ccatagtttg cgcctccctc agcatcaatt gactcaataa tttggttgaa
     7501 gccagtattt ccgatgtctg gtcacttcct ccgcgattaa aaaacaaagc acttctggaa
     7561 atgaagtcat tcaccgtatg gggaacagaa accatttttt cacccattct cgaaaaatga
     7621 aaattagttc gattattgag aatagagcca cacagggcaa taccaatcgc gcccccaaga
     7681 ttacgtgtta aattaaatac accagaggct aacttcagcc gttcttttgg aattcccccc
     7741 agcgttaatg ttacgatggg ggccatcgca aactgctgcg aaatccctct aattgcctgt
     7801 ggaaacagta actcctgcca tccccattcg tgggttatag gggtaaaaag atacattgaa
     7861 aacacaaatc cacccagccc cgccatcaac agccatcgca gatttatttt tttacttaac
     7921 cagaagtaaa agggaacaga aaataactgg aaaatacctg ttgtgcaaac ggcaaaacct
     7981 atctcttcgg catttaatcc gcgaacccgc cccaaaaaca caggtattaa atatacagta
     8041 gagaatattc caacccctcc agaaaaagaa aaaaaacatc ccagtgtgaa atttttatcc
     8101 ttaaaagcat gaagatccat tatcggattg gatattgtaa gtgtacgcgc agcaaataaa
     8161 ataaaactca ccaatgccag aactgatgtc agaaaaatag tattatcatc cagccatccc
     8221 cagcgcgctc cttcttcaag ggtatattcc agacatccca gtgtcatggc caacaggata
     8281 atactcggat aatcagcaac tttcagtaaa gagagatcag gtttatcaaa attaaccaga
     8341 aaaggaatac tcaaaactaa atatatgcca ggtaatatat tgatataaaa tagccatcgc
     8401 cagtcgaggt tatcagtgat ccagcccccc agagttggcc ctagcgtcgg tgacagtgag
     8461 gccagcgcac tgactaccgc agcagccaac cccaactctt taccctggta ataaataaac
     8521 gccgtcgtga aaactaaagg gatcatggat gcgccagcag ctccctgtaa agcacgaaaa
     8581 aaaatcatga tctgaatatt ccaagcaagt ccacacgcga tactcattaa agtaaatatt
     8641 cccgcggata gagtaaaaag ccaacgagtg gaaaataccc gtgacagcca cccagagagc
     8701 ggaataacaa taatctcagc aattaaatag ctggtctgaa gccaggccat ttcgtcttta
     8761 cctgcggaca gaccaccacc tatttcattt agggatgacg atacaatttg aatatcaagc
     8821 tgagcaataa ataatcccat acacatactg gcgaaagcaa tatgtttacg catagacatc
     8881 atctctcatc aacactgacg gtgacggaca gtcccgggcg aagaagttgc tttaattcct
     8941 ttgcgtcgtc aaatgcaatc cgtaccggga cacgctgaac aattttggtg aaattgccag
     9001 tggcattttc tatcggaatc aagctgaaac tggctcctgt cgctggggaa aggctttcaa
     9061 tgtgaccgtg aaacacttcc cctttgagaa tatcagcacg gatctcagcc ttcattcctg
     9121 gcttcattcc cgctatttgg ttttctttat aatttgcatc aacccacaac tcactgactg
     9181 gtactagtga aactaacgat gtgccgcctt ccacccaact gcctgtatgg gcgctgcggt
     9241 ttgcgacaat gccatcaatc ggcgcacgaa caagggtata ttccagatcc agtagtgcct
     9301 gagtcaaagc ggcctgaact tcttcgatac ttgcacgtac gttttcttcc tgagcagata
     9361 aaactgccag ccgttgcttc tccaccagga aatcgttcgc ggctttgcgc tcctttgctg
     9421 cgacctgctg gtagtcaaac ctggcgttat caataatttg ttgcgatatt gccgctgatt
     9481 gtgcgagttt ttcataacgt tcagtatctc gcaggcgctt ttgctcctca tgttttactg
     9541 cctgccatgt ttcactggca ctttgaatta tcgactgctg catcgcaata gtggcttgaa
     9601 tgctttcgag attggctttg ctacttttta tttttgcctc aagcctggcg acatttgcac
     9661 gataatcccg atcatcgaga cgcaggataa tatcgccttt ttttacactc tgattatcgc
     9721 gcacctctat agcagaaata taaccagaaa ctttacttgt caccgtggtg atattaccac
     9781 caatgtaagc atcatccgtc gtctgtataa atcttccttt gcttacccac cagataaaaa
     9841 agacaacgcc agccaaaaga ataccgatcg ctaccacccc aataagctgt tttttagaaa
     9901 ttatcatcac tctttacacc gtatatatcc ggaaacttgc atacgtcata tttaaaattt
     9961 aacatggctt atttgatgat ttctgacaaa atacctactg taaatgacaa tcacactgca
    10021 acccaaagca tcaccagggc atcacattat cggactggat tcggaacatc tgaatggagg
    10081 tacagttccc tggcataaac atctctatgc ccagttgctt tacccggctg aaggagtcgt
    10141 tcgtgtatgg gctggagaaa gcgtctggct agtgcatgcc agcagcgcgc tttggctgcc
    10201 cccacaaatg ccgcataagt ttgttgcgac aggcaacgta cttttaaaaa ccgtactggt
    10261 ttcagaagcg gaaagtgaaa cgctgggaaa agtttgcttc atgacgggta tttcacccct
    10321 gttaagggaa ttactaattg caattaacca acttccaccg tcgcaaagta ccacagataa
    10381 acaacagtta cgtttttcag ccctcgagac actgatactt caggaaataa aaatgggggt
    10441 gaaaatgtca cttgaactcc cttggccaaa tgatgagcgg ctacagcagc tttgtgagaa
    10501 tttgctaaac aaccaagggt atctgccaac actggataat ctagcggata aaattaacgt
    10561 cagtagccgt acactcatgc gcttatttgt taaagagacg ggattaacat ttcgccactg
    10621 ggttcagcaa atgcacgtta tttctgcagt gacgcttctt gatgatggat attcgttgac
    10681 caaaattgcc catcgtctgg gctatgcctc agctgaatcg ttcggcaata tgtttaagcg
    10741 tcgaacgggc tactcgcccg gtaaatttac tcgtcgatta acgatgcatg attatgcaat
    10801 cacaagacaa atgatttaac ttatattttc gtgaaatctg tcactgaaga aaattggcaa
    10861 cggatgggta aaaccgttat aacactgtca ccggtcacca ggaccccagg ccggatttaa
    10921 gacgaggatg cactgctgtg tgtactgtag agtctggcgg atgtcgacag gctctatttt
    10981 tttattcatt ttttagccct gtaaataacc acattctcgc cgggattggg gaatgagtga
    11041 cgagatcagt ggtgtctggc ggctatcacg ccacagatca aataacagat aacctacggt
    11101 aaaatttcgc tgactggaat tatcccaccc tcgatccatg tgatggcttg ccctcatttc
    11161 ttcaggcaga aaaatcaaaa aatcgcttaa tactatcaga ctgcgacaaa ccagacgcga
    11221 aactgggtac ttactattcg ttagtcttac cctatccact tatctttttg gtggtatggc
    11281 tgctgatgtt gctggcgtgg tatcttgttg gcttgccgat aggtccgggt atttacccac
    11341 gtttgtctta agagagaacg gatgctgaga ttacttgaag aaaaaattgc cacgccactg
    11401 ggtccactgt gggtgatttg cgatgagcaa tttcgcctgc gggcggttga atgggaagag
    11461 tacagcgaac gcatggtgca gctgctggac atccattatc gcaaagaagg ctatgagcgc
    11521 atttctgcca ccaacccagg tggtttaagc gacaagctgc gtgaatattt tgccggtaat
    11581 cttagcatta ttgatacgct tcccactgcc acggggggga cgccatttca gcgcgaagtc
    11641 tggaaaacac tgcgcactat cccctgcggg caggtaatgc attatggcca actggctgaa
    11701 caattaggcc gccctggcgc ggcgcgtgcc gttggtgcgg caaacggatc gaatcccatc
    11761 agcatcgtcg taccttgcca tcgggttatt ggccgaaacg gcaccatgac cggatatgca
    11821 ggcggagttc agcgaaaaga gtggttattg cgccacgaag gttatctttt gctgtaaaca
    11881 ttaaacaatt tgtgccagct tgttcacact tttatgtaaa gtcaccctta acaacttaag
    11941 ggttttcaaa tagatagaca tatatttaca tctaatatcg gaattctctg ctgttaaggt
    12001 ttgcttagac ttacttgctc cctaaaaaga tgttaaaatt gacaaatatc aattacggct
    12061 tgagcagacc tatgatcccg gaaaagcgaa ttatacggcg cattcagtct ggcggttgtg
    12121 ctatccattg ccaggattgc agcatcagcc agctttgcat cccgttcaca ctcaacgaac
    12181 atgagcttga tcagcttgat aatatcattg agcggaagaa gcctattcag aaaggccaga
    12241 cgctgtttaa ggctggagat gaacttaaat cgctttatgc catccgctcc ggtacgatta
    12301 aaagttatac catcactgag caaggcgacg agcaaatcac tggtttccat ttagcaggcg
    12361 atctggtggg atttgatgcc atcggcagcg gtcatcaccc gagtttcgcg caggcgctgg
    12421 aaacctcgat ggtatgtgaa atcccgttcg aaacgctgga cgatttgtct ggtaaaatgc
    12481 cgaatctgcg tcagcagatg atgcgtctga tgagcggtga aatcaaaggc gatcaggaca
    12541 tgatcctgct gttgtcgaag aaaaatgccg aggaacgtct ggctgcattc atctacaacc
    12601 tgtcccgtcg ttttgcccaa cgcggcttct cccctcgtga attccgcctg acgatgactc
    12661 gtggtgatat cggtaactat ctgggcctga cggttgaaac catcagccgt ctgctgggtc
    12721 gcttccagaa aagcggtatg ctggcagtca aaggtaaata catcactatc gaaaataacg
    12781 atgcgctggc ccagcttgct ggtcacacgc gtaacgttgc ctgattcttc cgcataactc
    12841 actatccttc tgtcatatca ttaaattttt ctgatttatt gatctgacag aaggttcatc
    12901 actgtttcat tcaccagata tgggttaatc ttttaattac aaactgcgtt gacagttgtt
    12961 gtaaggagac cctgtatggc tatgtatcag aacatgctcg ttgttatcga tcctaaccag
    13021 gacgaccaac cagcattgcg gcgagctgtt tatttacatc aacggattgg tggcaaaatt
    13081 aaagcctttt tgccgatcta tgacttctca tacgaaatga ccaccctgct ctctccggac
    13141 gaacgtaccg ctatgcgtca gggcgtcatc agccagcgta cagcctggat ccacgagcag
    13201 gcaaaatatt atctcaatgc tggcgttccc attgaaatta aagtggtctg gcataaccgt
    13261 cctttcgaag ccatcattca ggaagtgatc agcggcgggc acgatttggt gctaaaaatg
    13321 gcgcaccaac atgaccgtct ggaagcggtg atttttacgc caacggactg gcatctgtta
    13381 cgcaaatgcc caagccccgt gtggatggtg aaagaccagc cgtggccgga agggggtaag
    13441 gcgctggtgg cggtgaatct cgccagtgaa gagccgtacc ataatgcgct caatgaaaaa
    13501 ctggtcaaag agacgatcga actggcagaa caagtcaacc ataccgaagt tcatctggtt
    13561 ggcgcttatc cggtaacgcc aattaatatc gcgattgaac tgccggaatt tgacccgagc
    13621 gtttataacg atgccattcg tgggcaacat ttgctggcaa tgaaagctct gcgacagaaa
    13681 ttcggcatta atgaaaacat gacgcacgta gaaaaaggtc tgccagaaga ggtgattcct
    13741 gatttggcgg agcacttaca ggcggggatt gtggttctgg gcacggtcgg acgcaccggt
    13801 atttcagcag cattcctcgg caacacggcg gaacaggtga ttgatcatct tcgctgcgac
    13861 ctgctggtca ttaaacctga ccagtatcag acacccgttg aactggatga cgaagaagac
    13921 gattaacgac tcttcaataa ctgacaaggc ccgagttatc gggcctattt tttacttact
    13981 gctcttcgcc gccaaggaaa taaattccca acgggattgc cagcaacaca gtaaagacca
    14041 ggctataaac aaaaatcatc gatgactgaa tcacatacat tgatgtcgtc cactcagaca
    14101 gcggaatatt gtactgttct ataacgccgc cgatggtcgc gcgagtcaca accgacgccg
    14161 caataatgaa aaccgccaac aaaccaaaga gaaatttctt ccctttcgct gacttcagtt
    14221 tcgccataat catgatgtaa tccttgtgca gacaaatttt ttgttaccta aacgtaacaa
    14281 taccatgaca tttcaccgtt gtctgctctg aaaacctcac ctcttagctg gatttacaat
    14341 caacgcattg attagttagc taatgttgct acttccttcc ctgactattg atgatctgaa
    14401 tgaattgtcg cggtaaaata gtcccgccag gggtttccgg catgacgaca attatctgga
    14461 ggagcctgat aaaacaatga tcgctgaact gtttacaaat aatgcgctta atctggtcat
    14521 tattttcggt agctgcgcag cattgattct gatgagcttt tggtttcgcc gtggaaatcg
    14581 taaaagaaaa ggatttttat tccatgcggt gcaattttta atctacacca taattattag
    14641 tgctgttggt agcatcatta actatgttat agaaaactat aaactcaaat ttatcacccc
    14701 aggcgttatc gattttatct gtacgtccct gattgcggtt attctgacga ttaagctatt
    14761 tctgctgatt aatcagtttg aaaaacagca gattaaaaaa ggtcgcgata tcaccagtgc
    14821 gcggatcatg tcgcgcatta tcaaaatcac cattattgtg gtgcttgttc tgctttatgg
    14881 cgaacatttc ggcatgagcc tttctggctt gttgaccttt ggtggtattg gtggtctggc
    14941 tgtcggtatg gccggtaaag atattctgag taacttcttt tccgggatta tgctctattt
    15001 cgaccgtcct ttcagtattg gcgactggat ccgttcaccg gacagaaata tcgaaggtac
    15061 agtagcggaa attggctggc gaattaccaa aattaagacc tttgataatc gtccattgta
    15121 cgtaccgaac tcgctgtttt cgtcgatcag cgtagaaaat cctggacgaa tgaccaaccg
    15181 gcgcattacc acgaccattg gtttacgtta tgaggatgcg gcaaaagtgg gcgttattgt
    15241 cgaagccgta cgtgagatgc tgaaaaatca cccggccatc gaccagcgac aaaccttact
    15301 ggtttatttc aaccagtttg ctgattcgtc attaaatatt atggtttatt gctttaccaa
    15361 aaccacggta tgggctgaat ggcttgctgc acagcaagac gtttatttga agattatcga
    15421 tattgtacag tcacacggcg cggactttgc cttccccagc cagacgctgt atatggataa
    15481 cattacaccg gcggaccagg gtcgctaaat cagacatcac tggcgttatc cacaagggta
    15541 acgccagttc tcatcacatc aatgcttcac aatatacata gtccgactgt acgccacatc
    15601 ttcagggttg ttaatgggat aacctttcag ccacggcttg attaatcgtc cattggtata
    15661 ttgataaatt ggtgcaatcg gtgcttgctc catgaggatt ttttctgccg cgttgtaatc
    15721 ggcattacgc gctttaacgg tattttccgt cgatgcctgg gccagaactt tgtcatatgc
    15781 cggattgtta aagcgtgaaa tattcccgga atgcgttgac gttaataatg tcaggaaagt
    15841 ggagggttca ttataatccc ctacccacga ggcgcggata acatcaaaat tgccggtatt
    15901 acggctatcg atataggttt tccattcctg gttttgcaat ttaacatcta cgcccaggtt
    15961 ctttttccac atcgatgcta cagcaatcgc aattttttga tggttttctg aagtgttata
    16021 caaaagcgtc agcttcagcg gtttttgcgg accataacca gcggcgctca acaaagtttt
    16081 tgcctgcgca ttcagttctt cctgactcat ttgttcaaac ggcgaaggtt ccggcgtaaa
    16141 tcccgcggta acatctggtg taaaatgcca cgctggcttt tcgcccgtcc ccaacacttt
    16201 ttcggtcatc aggcggcgat ctatcgtcat acttaatgcc aggcgaacgc gctgatctgc
    16261 cgtcggccct ttttgcgtgt taaacgcata ataataggtc ccgagctgcg gcggcgtata
    16321 aacctgcccc ggaatatcct tcaacagctt ctgatacata tttttcggga aggattcggt
    16381 gatatcaata tcccccgcga gataacgctt agtggctgcg gattcctgat taattggcag
    16441 gaaggtcact ttttgcagta ccgttttggc gttatcccaa taatgggtat tcggcactac
    16501 gaccagtttt tcattgacta cgcgctcttt aagaacataa gcgccattgc cgatcagatt
    16561 tccgggtttc gtccactctt tactgctttc tacgttggct ttttgcaccg ggaagaaggc
    16621 aaagttagcg gttaaattca caaaccacgg caacggttta tcaagctgga ttttcaaagt
    16681 atgggcatca actgcggtaa cgccaagctg gtcaggcgtg gctttaccat caataatcgc
    16741 ctgtgcgttg ttgattcccg ccagcgcggc aaaccatgca aatggcgaaa gcgttttcgg
    16801 gtccaccaga cgttgccagc tgtagacaaa atcttgcgcc gttaccggtg tgccatccgc
    16861 ccattttgcg ttatcgcgca gggtaaaagt ccagatacgg ttgtcattac ttttccactg
    16921 agtcgcaacg ccggggacaa tctccccttt ctcgttctga ttcaccagtc cttcaaacag
    16981 atcgcgaatg acctgaatct ccggcaggcc cacggcttta gcgggatcca gcgacgctgg
    17041 ctcatcttta atgtggcgca ccagctcctg cttctctgcc agtactgtgc cgctcggaac
    17101 ttcagcagca tacgaaagag aaatgctgct gaccaacagc gcacaacacg tgactgaaac
    17161 agagtgcttc ataagtttcc ctctaaccga cattaaaatt gatgcgtaat tatttgtttc
    17221 gccttaaaga aatgcaaaca acttccatca aaaaagtgac aaaggaagca tcaaatgttt
    17281 taagtatcaa tatatcaaat cagatttagt gtaaataata gtctccaaaa tgcggtaaag
    17341 cacatagaac tccgaacact acgttcgggc ttcgcacatt caaacccgtt ttcggtatca
    17401 taatcagcat ctgtcgccat tgtgcgaaga ataaaaaata accaaaacgt tgaaaggaac
    17461 tgagaatacg ttaagagaag aattaaatta atgtatcagc aagtagtgct aaacagcacc
    17521 tttatacttc agcctatcta taaataatga gaatgccgag ccagcatgtc gacggtgtgg
    17581 atagtacagg tgataaccgg gtaaatctgg tgtgaattta tccaaaacac gtatcagttt
    17641 tttttcttta atagcccgct ccacctgatc ataaggtaga tacgccaatc catgcccatc
    17701 aattgcagca tcaatgatca gatctatcgt attcagtaaa agctgacctt ccatgcgaac
    17761 acgaacttca cgtccaccgc gtattaatct ccagcgattt gctgtacccg atgtgggaag
    17821 atacaaatta attgcctgat gatctattaa ttgtgacact gacgttggag cacttcgacg
    17881 agaaaaataa tccggtgagc caacaatagc cattggtatg tctggcccga ttcgaatggc
    17941 gatcatatct ttatccatct ccccacccag acggacgcct gcatcaaaac gttcagaaac
    18001 gacatcggtc aaaccataat caatggtaag ctgaatatca atttcaggat gcgatttcag
    18061 gaatgtgcgc atggctggta acaatatcgt ttttgctgca tgttctacag tagtaatacg
    18121 tattgtcccg gatgggcggt tctgcagatc gctcagggat gtcagggcag aatctatgtc
    18181 atgcaacata gggccaagaa cagacaaaag atgctcgccc gcttcagtgg gtacaacgct
    18241 gcgcgtggtt cgcgtcagaa gccgcaatcc caatcgttct tctatacggc gcactatctg
    18301 gcttaaagct gactgcgcca tgctcaggcg ggctgctgcg cgagtgaagc tacgctcctc
    18361 tgcaacaacg acaaacgcca tcagatcagc gatttcttca cgcttcattc agtatctcca
    18421 tacaatctat taatcattta aatgataggt ctaatcatga ttttgggtct aatcaactta
    18481 atgatcaata tctatagtga tatcaccaac cgttaaaacg aaccgacaac tccatgagga
    18541 acggaatgat gaataataaa gtcagcttca ctaacagcaa taatccaacc atctctttgt
    18601 ctgcagtgat ctatttccct ccaaaatttg atgaaacccg tcagtatccg gcaattgtgg
    18661 tatctcaccc aggtgggggc gttaaagagc aaacggccgg aacctatgcc gaaaaactgg
    18721 cggaaaaagg atttgtcact attgcttatg acgcatctta tcaaggtgaa agcggcggcg
    18781 agccgcgtca gttagaaaac ccatacattc gtactgaaga cgtcagtgcc gtgattgatt
    18841 acctgacaac gctttcttat gtcgacaata cccgaattgg tgcgatggga atttgtgccg
    18901 gtgcaggata tacagccaat gctgcaattc aggatcgccg catcaaggcc atcggtactg
    18961 ttagtgcggt caatattggt tcgatgttcc gtaatggttg ggaaaacaat gtgaaatcta
    19021 ttgatgccct accatacgtt gacgcgggtt caaacgcccg aaccagcgat attagcagcg
    19081 gagaatacgc cactatgcca ctggcaccaa tgaaggagtc cgatgcgccg aacgaagaac
    19141 tgcgtcaggc ctgggaatat taccacaccc ctcgcgcgca gtatccaaca gcaccgggtt
    19201 acgctacttt gcgcagcctt aaccagatta ttacctatga tgcttaccat atggcggaag
    19261 tgtacctgac tcagccgata cagattgtgg cgggcagcct ggctgggagc aaatggatga
    19321 gtgacgacct gtacgatcga gcatcaagcc aggataaacg ctatcacatt gttgaaggcg
    19381 caaaccatat ggatctttat gatggcaaag tctatgtggc tgaagtaatt tcagtattag
    19441 ctccgttctt tgaggaaact ctgtaatgaa acatattcaa atccgtaata gtgatatggc
    19501 ctggcatatt gctgccaata atctgggaaa agtttcatga aaaatgtact gattcttggt
    19561 gctggcggtc agatagcccg ccatgtgatt aatcaactgg cagataaaca aaccattaaa
    19621 caaactttat ttgcccgtca gccagcaaaa atccacaaac cctatccaac taatagcaag
    19681 attattatgg gggatgtact gaatcatgca gcactgaagc aggccatgca gggacaggat
    19741 gttgtgtatg ccaaccttac gggggaagat ttagatattc aggcaaattc agtgatcgct
    19801 gcgatgaaag cctgtgatgt taaacgtctg atctttgttc tttccctcgg tatttatgat
    19861 gaagttccag gaaaatttgg cgaatggaat aatgcagtta ttggtgaacc cctaaaacca
    19921 ttccgcaggg ctgcggatgc aattgaggct tctggactgg aatatacaat tcttcgccct
    19981 gcctggctga ctgatgaaga tattattgat tatgagctta cctcacgcaa tgaaccattc
    20041 aaaggtacga tcgtatcacg taagagtgtc gcagcattaa tcacagatat catcgataaa
    20101 cctgagaaac acattggtga gaatataggc atcaatcaac ccgggactga tggtgataag
    20161 cccttcttca tgtaaatcaa ttatatagct accatcgtac tgtactatgt gcagtacgat
    20221 ttattaaact tattaaggtg aactgatcaa tcagatgcga ttaacatgtg tagaaccagt
    20281 aagaataaaa tacgccatgt atataacatt acgacaattc taatatctgc acatcaatga
    20341 aaatgcaaac aacttccggc aaaaaagtga tacaagatcg atgacatagc gttgaagaaa
    20401 aggatttgat aatccgcaaa atttgcacaa cactgcctgt aatacttcct gaaccagaga
    20461 cgatcatgac cgtaactcgc ccacgcgccg aacgcggcgc atttccgccc ggaacagaac
    20521 attacggacg ttcattattg ggcgcgccgt taatctggtt tccggcccct gcagccagtc
    20581 acgaaagtgg tttgattctg gctggcactc acggtgatga aaactcttcg atcgtcacgc
    20641 tctcctgtgc tctgcggact ttgacacctt ctttgcgccg ccatcatgtg gtgctgtgtg
    20701 tgaatcctga cggctgccag ttagggttac gggccaatgc taatggtgtg gatttaaacc
    20761 gaaactttcc ggcagcgaac tggaaggaag gtgaaacagt ttatcgctgg aacagcgccg
    20821 ctgaagaacg tgatgttgta ttactgacag gtgacaaacc tggctccgaa cctgaaaccc
    20881 aggcgctgtg ccagcttata caccgcattc aacctgcctg ggtggtctca ttccacgatc
    20941 cgctggcctg tattgaagat cccagacaca gcgaattagg tgaatggctg gcccaggcgt
    21001 ttgaattgcc tctggtaacc agcgtcggtt atgaaacgcc tggctctttc ggcagttggt
    21061 gtgcagatct caacttgcat tgcatcaccg cagagtttcc acccatctcc tccgacgaag
    21121 ccagcgaaaa atatctcttt gcgatggcaa acttgctgcg ctggcatcct aaagatgcaa
    21181 ttcgcccgtc gtgaactgaa gcgccggttc cacatctacc gccagccagg tcggtccgtc
    21241 aagatcggcg aaactgacct gcggcaccag cggtaaagcg gcgctaatgg cacgagaggt
    21301 acacaacatg cagcccagca tcagacgaaa accttgtgca cgcgcttcag tcgccagcgc
    21361 cagcgcttcc gtcagaccac cggttttatc aagcttaatg ttaaccatct catagcgccc
    21421 tttcagcgcc ttcagattgc tacgagtatg acaactttca tcagcacaaa tcggtaacgg
    21481 atgaataaaa ttctccagcg ccgcatcgtc ctgcgcagga agcggttgtt caagcatcgc
    21541 aacgcctaaa tccgccaata gctggcaacg cgccgccaac ccttctgcac gccaggattc
    21601 atttgcatca acgatcagcg tcgcatcggg cacagctgtg cgaattgcca ccatccgctc
    21661 actgataaga tggttatcca gcttcacttt cagtaatttc gcgcctgcct gccagagtgt
    21721 tgatgcacta ttggccatct gatcaggcgt accgatgact atcgtctgtg ccgtggtgac
    21781 tgtctcggga agcgttatgc cgatcaaatc agccagcgat tgctgctgtt ttcgcgccgc
    21841 cagatcccac aatgcacaat ccagcgcatt acgtgctgcg ccggcaggga ggattttttg
    21901 caactcctcc cgtgtcagcc ctttctctag ttgcggcacg acgctcataa tttgcgccat
    21961 taccgaggca tcgctttccc cataacgcgg atacggcgtg cattcaccgg tgcctttgat
    22021 accctcttct tccagttcaa ccaccaccac gcgcgcttca ctgcgacttc cccgagcaat
    22081 cacaaacggg gtatgtaagg gccaggcctc ctcaaatacc ttaacggttc tcatctttac
    22141 tccttgttgt cgcggtggtc tgcggattaa gcgcaaatag cgtttgctgt gttattgaca
    22201 gttagcataa actaggtgtg acgttaacta tatgtaaaca ggaaagataa tcatgtcaca
    22261 aaccgttcat ttccagggca acccggttac agtcgccaat tccatcccgc aggcgggtag
    22321 caaagcgcag acttttactc tcgtggcaaa agatctgtct gacgtcaccc tcggtcagtt
    22381 tgcgggtaaa cgcaaagtgc tgaacatttt cccgagtatt gataccggtg tttgcgccgc
    22441 atcagtacgt aagtttaacc aactggcaac cgagatcgac aacaccgttg tgctgtgtat
    22501 ctctgccgat ctgccgttcg cccagtctcg tttctgcggc gcagaaggtc tgaacaacgt
    22561 tatcaccctc tccactttcc gtaacgctga attcctgcaa gcctacggtg tggcaattgc
    22621 tgatggccca ctgaaaggtc tggcagcgcg tgccgttgtg gttattgatg aaaatgacaa
    22681 tgtgattttc agccagctgg tggatgaaat caccaccgag ccggattacg aagcagctct
    22741 ggctgtactg aaagcataag ttaatatgcc tgatggtatt gcaccatcag gcatattcac
    22801 gcttactctt cgttcttctt ctgactcaga ccatattccc gcaacttatt ggcaatcgcg
    22861 gtatgtgaaa cgccgagacg ttttgccagt ttgcgcgtgc tgggataatt gcgataaagc
    22921 tgggttaata ccgagcgttc aaaacggctg gtgatttcgt ccagcgaacc ttccatcgca
    22981 tcttcgccca cggctaccgt tgcggcgtca taatccggca acaaaatatc ctgtggacgc
    23041 agctcataac cgtccagttg tgtcagtgca cgatagatag cgttctttaa ctgccgcaca
    23101 tttcccgtcc acgcataacg cgtaagtaca gtattcagat cagcggccag tttcggacgc
    23161 ggcacgccct gctcgtcggc aaagcgggcg acgaacagct cggttaacgg catgatgtcc
    23221 tgcggacagt cacgtagcgg cggcagattg agcgtcaaca cgttcagacg ataatagaga
    23281 tcttcacgga acacgccttt ttgcaccagt tcgaccagat tcttctgcgt agcgcaaatc
    23341 acccgcacat cgacatgcac ctcatggtct tcgccaaccc gacggaaggt gccatcatta
    23401 aggaaacgca gtaatttcgc ctgcatccgt ggtgacatct cacctatttc atccaacagc
    23461 accgaaccac cgttcgcctg ctcaaagaac cctttcttcc cttccggagc atgaccaaac
    23521 agttcactct cgaccgcatc ttccggtata gacgcacagt tcagcgccag gtaaggtttg
    23581 ctcgctctgg ggcttgcctg atgacaggcg taggcaaaga gatcttttcc ggtgccggta
    23641 tcacccgtaa tcagcagtgg cgcgcttagc atcgccagtt tctgcgcctg ttcgacaaca
    23701 tgcttcattt tcgggctgac agcgacaatt tgactgaagg cgctgacatc ctgggcggcg
    23761 acattttgca actgacggcc catacgaatc gttgatcgca gcatcaccac cgcaccggtc
    23821 aggacgtgtt gatcattttc atcctgaaga taaacaggcg taatctccat caggaaattc
    23881 tgcccattaa taacgacatg ctcgttatgc gaatcttgcg gttcgctttc cagccagcgt
    23941 aaaaaattaa agccgttaat caattgcgcg gcggtatggt tgcgcaggcg atccaatttt
    24001 tgcccaaaaa gctgacagct cgccgggttc gccatatcca ctttgctttt catatcgaca
    24061 gagagcacag gttcaggcaa cgcctccagt aacgcgctca acgccagatg ctcacgttcg
    24121 gaaggcatcc acgggacagt acgcacatcg gtaacacctg caatacggcg tatttcggcc
    24181 atcagactgc tgaaactctc aaactccagt tcagcaaaat tgaggtagat tcgcccaatg
    24241 gggtcaatct caataccgcg taaatcaatg cctcttagca cgagtagatc gagtaattcg
    24301 cgggtcagac cgagtcggtc ttcacaaaag acttccagac gcatgggaac cttcacctga
    24361 aaaaagaaca attaatatga tgatatgaca ctatttggat agcaggaagg tttctgtcaa
    24421 caatcattga cacaaagacg gaaaaacggg cacttcggcg taaagatatc cggtcagcac
    24481 ccgatattgc attatttttc gctgggcgtt ttgccttttt gcagagtttc tttcacctga
    24541 ccgataagct gacgacggaa atccccgagg cgtggcttgt catcgtcaat ccacggcagc
    24601 gggcggcaaa gctccatagc tttaatcccg agtcgtgccg tcagaagtcc agcaccaatc
    24661 ccctgagctg cccgggtaga caaacgcgca gcgagatctt gcgacatcca gtccatcccc
    24721 acttcgcgca ccagttcgct ggctccggcg aaagcgatat tcagcaatac cagcttaaac
    24781 aggcgcaaac ggctgtaata tcccagttca atgccataca gcgtggcgat gcgattaatc
    24841 aaacgcagat tgcgccaggc gataaacgcc atatccacca gcgccagtgg gctaacggca
    24901 atcattaacg ttgattccgc cgctgagcgg ctgatttcgc gccgcgcctg ggcatctaaa
    24961 actggctgga ccaggtgagc atacaaactg accacttcac gatcgttctg cgtttcatgg
    25021 attgaggcat accagcgctg cagcgccgga tgtgactgat cgatgcccgc ctgctgcgcc
    25081 agtttttcgc agaatgcacg gcctttaccc gtgccgtgac tgtgcaacaa atcgcgcgct
    25141 tcatcgcgtt catgggcgcg ctgtcgcaag cgccataagc gccgccactc tgttaccaca
    25201 gaacctacgc cagcgccgat aatcaatgcc ccagcggcac atccacccag cgccacccag
    25261 tcctgggttt gccaggcgtt cattgtccac tgcacgccct gcccgacaac gcttgcgcca
    25321 aacagagcca gcccgcccat caccattttg cgccacaggc tgcgtttcgg acgtaacgct
    25381 gcgtccatca ccgcttcaac ttgcccctct tcttcctgtg cttcgtcgag cgtggccggg
    25441 gcaaaatttt gcgcctgatt ttcgtcaaag gtctgctgcg ccctgaattt tggattctga
    25501 tcgacctcca gtggaccgtc gaaatcaata cgtggtttta acggttcggt catcgcaatt
    25561 tatctcctat taaaaattcc agcgcagcat caagacgaat atgcggtagc ggtttgtcga
    25621 catccatcac ctgcggacga aacgcctcaa actggaagcc ttgcttatcc cagaacgcct
    25681 gacctggcaa acgtgcggga acttcgccag gataaacagt gagcggtgcg ccatcgctga
    25741 gtcgattacc gcgcagcgcc gggattttct caccgttaac atcaatcatt ccgctggtgg
    25801 tcgcctgaac agacgccagc cccaggcagt ccatactgat cccttcgaac gccgcatttt
    25861 gccatgcatc ctgaatcagt tgttgcagca atgaaaccat attggcgtgc tgatcgatgg
    25921 tcacatggtc cgctttagtg gcagcaaaca atagcttatc gataaccggc gaaaacaaac
    25981 gccggaacag ggtacgctgc ccgtagtgga aactttgcat cagctgcgtc agcgccagac
    26041 gcatatcatt aaatgcctgt ggcccactgt tgagaggttg caggcaatcc accagcacaa
    26101 tctggcggtc aaagcgcaga aaatgattct tatagaaccc cttcaccact ttctcgcagt
    26161 aataattaaa ccgctcgcgc aacattccgg cattagtgtg cttatcggcc tgcgccagtt
    26221 tggactcgcc ccaggcatcg acatccggcc acgggaagaa ttgcagcgcg ggtgctcctg
    26281 ccatatctcc cggcaagaca aagcgcccag gctgaataaa gtgcaacccc tgctgtttgc
    26341 agtgatggag atactcggtc caggcggcgg caatgtctgc cagccggttt tcgtcggcag
    26401 gcgctagcgg gtccagccct tcgcacatca ttcgccattt cgccgaccat tcgccgcgct
    26461 gaccattgag taagcccgtc atctggcgcg accagcttaa atagtcctgc gccagcatcg
    26521 gcaggtcgag caaccattcg ccggggtaat ccacaatctc cagatacagc gtggaggtat
    26581 ccttaaagtg gcgcagcagc gaatcgttcg atttaaaacg taacgccagg cgaatttcac
    26641 tgacaccgcg cgtaggcgtc ggccaggcgg gaggatcgcc atataactgc gccaaccctt
    26701 catcataggt gaagcgcgga atgccaaagt cacgctgggg aatgcgtttt acgcccagca
    26761 ggcgctcttc acgcaccgca cttaaaagcg gcaaacgtgc tccggcatga atattgagca
    26821 actgattaac catcgcggtg ataaacgctg ttttgccgct gcggctaagt ccggttacag
    26881 cgaggcgcag atgtctgtcg acaccccgat tcaccagcgc attgagttca tttttaagtc
    26941 gcttcattgc tgtcctgtgc tgctctgaag accagaaaaa aaatcgttcg taaggatatg
    27001 aatgtggggg ccaggccatt gattatcaac tacccgtgtt gtcatcgacg ggcgaactcc
    27061 ataagatgtg cagcattcac gttcggacgg agttcctgac ctatgtcccc tactatttat
    27121 gatattgcca gggttgcagg cgtatcaaaa tccaccgtat cacgcgtgct gaataagcaa
    27181 accaatatct ccccggaagc gcgcgaaaaa gtgttacggg ccattgaaga attacagtat
    27241 caaccaaaca agctggcccg cgcgctgacc tcttcgggtt ttgatgccat tatggtgatt
    27301 tctactcgtt cgaccaaaac tacggcgggt aatccatttt tctctgaagt tttgcatgcc
    27361 atcaccgcca aagcagaaga agaaggtttc gacgtgatat tacaaacgtc gcacaatccg
    27421 gcagaagatc tgcaaaaatg cgaaagcaaa attaagcaga aaatgattaa aggcattatt
    27481 atgctaagtt cgcctgccga tgaatccttc tttgcacaac tcgacaaata cgagatcccg
    27541 gtggtggtga tcggtaaagt tgaaggtcaa tacagccatg tttattccgt cgataccgat
    27601 aattatggcg acagtattgc gctgaccaat gcgttaattg aaagcgggca taagaatata
    27661 gcctgcctgc atgcgccgct tgatgtacaa gtttcagtgg atcgggtaaa tggttataag
    27721 caaagtctgg ctacgcataa tattgcagtg cgtgatgaat ggattgttga cggcggttat
    27781 acccatgaga cagcattaaa agcagcacgg gaattattaa gccagtcacc gttgcctgag
    27841 gcagtgtttg ctactgacag cctgaaatta atgagtattt atcgtgcggc ggcagagaaa
    27901 aacattgcta ttccgcagca gttagcggtg gtgggttata gtaatgaaac gctgtcgttt
    27961 atattaacgc ctgcaccagg cggcatcgat gttccgacgc aggagttagg tcaacaaagc
    28021 tgcgagttat tattccagtt aattgccgga aaaccgtcac cacaaaatat taccgttgct
    28081 acgcatatgt cgttgaaata aatgtatgcc ggatttggcg ctcgccccgc atccggcaat
    28141 ttagcacatt atcagaacga gtaattcacc ccaacacccg cataatggaa tttatcgctg
    28201 tcgccttcgt cgtgatcctg ccactcaaac gcgtattcca gcgaaacgga aagaccattc
    28261 tggaaatcat aaccgtaaaa taaacccaca cggttaaaat catggccttc acgttcaata
    28321 tcatcctgcc agtcccagtt actccagcga tccagcccaa tgcgcgtata cggcgtcacc
    28381 gagtggttgc cgagcgtcag cggcaaatag gcgcgaattt cttgcgtgga aaactcaccg
    28441 ttattgcggc tatcatccat attgaaacca cgctcgagat aatagttcac tcgcaaggca
    28501 accgtttcgt tgaaggtata ttgcagaccc gtttccgttt cgacacgggt atcagcataa
    28561 ccggtcgtat tcagatcgtt ggcaaattta tacatcgaca gccaaccgtt gaaacgtaaa
    28621 tcgtcagtca gtttcacatc ccagtctggc gcgattttcc agcgctgcat atttgccgtg
    28681 tctttacccg gttcatcaac gtagtgataa ccatagttac ggaaaccacc agtcagaccg
    28741 agactgaaat catcgctttc gaggaactga taatgtacct ccagctccgg gcgatcaaac
    28801 cacgttccac gtttacccgc gctataatct accggccctt cctgataata ggccagagaa
    28861 attctccacg gcccgttggc ggcattaaaa tagacagaag gctctgccag cccatccata
    28921 tcttcgacat aaccctcgac gttttctatt tcgtacatcg cgccgatatt aaagtgccag
    28981 ttgttctttt cctcggcctg tgcgcaggcc attcccgcac acatcaccag tgcggtacag
    29041 ggtaataact ttttcattat tgttccttgt attatcctgg gagaatgcct tccccctgta
    29101 tttagcaaat tgctatttcc gtttctgcat caaagaaatg acatttagtc atatcaaaat
    29161 gaatagtgat attttctcct gcatgataat catttaacgc accagcacgg accactaact
    29221 cgtgcccccc aaccgtggtg tagagcataa attccgcacc ggttaattcc gccacgctaa
    29281 ttttggcgga aatgttattt tcttcttgcg catccggatg aatatcctcc gggcgtattc
    29341 ccatcacaat gggtttatgt aaactttcct gcgttttcag aaccgctaat ttctcttcgg
    29401 gaatggttaa tttaagtgtt tccgtaacga atttatcgcc atcgatcgtg ccgcgaataa
    29461 aattcattgc tggtgaccca ataaatccgg caacaaacat attcgccggt tggttataga
    29521 ccgttttcgg cgcaccgacc tgctgaacaa tcccatcctt cataatgaca atccgcgtcg
    29581 ccatggtcat cgcttcggtc tgatcgtggg tcacgtagat catggtggtg ttcagtttct
    29641 gatgcagctt gctgatctct gcgcgcattt gcacacgcag cttggcatcc aggttagaga
    29701 gcggctcatc cattaaaaac acgcccgctt cgcgcacaat cgcccgccca agcgccactc
    29761 gctgacgttg cccgccggaa agcgcgcccg gcttgcgttt caggtactca cgcaggccga
    29821 ggatttgcgc cgcccagtta acccgctcat caatcatctc tttggcgatt ttttgtatct
    29881 tcaggccaaa cgccatgttg tcgtagaccg tcatatgcgg atacagcgcg tagttctgga
    29941 acaccatcgc gatattgcgt gctttggctg gaacgtcatt cattcgtttg ccgtcgatca
    30001 acagctcacc gccgctgatc tcctcaagcc cggcaatcat acgcagggtg gtcgatttac
    30061 cgcagcccga cggaccgaca aacacgatga actctttatc ggcaatctcc aggctgaagt
    30121 ccttcaccac atgcacctgg ttatcgtaga tcttttgaat atgttgtaac gaaagctgtg
    30181 ccatgttgat tcctttgcta tacgttttgc cagaaggccg ataaccgcgg ccaggtcagg
    30241 gagtccgttg agggcaacaa taattgcgcc ccggttaagc ccgcgccgat ccccaccgag
    30301 cgcataccgc tggcgttaat ggcgtcaatg cccgcctgcg catcttcaat gccgatacat
    30361 gcctgtggcg gcacgcccag ccctgcacag gcggcgagaa agatttccgg gtccggtttc
    30421 gaatttttga gttgggaagc gtccgcgcag aaggtgaaaa actcgcgcag ctccagcgct
    30481 gctaaaatcg tcggcgcatt cagggagaca gaagccagcc caactggaat ctgctgtgcc
    30541 cggagatcta ccagcaaatt gtgaatgcca ggcagcacag cattaaccgt cagttcgcgc
    30601 agtgagtgga cgtaaagcag atttttgcga tacgccagtt gcgcccgttc ctgtgggtta
    30661 aaatcgccct ctttaccccc gtgctgcaga attcgccgca gggactcatc gcggctgatc
    30721 ccttttagga attcgttaaa ctgcgcatca atgctgatgc caatttcagc ggcaatctgc
    30781 tgccacgcct ggaaatgcag atgcgcggta tcggtgatta ctccatccag atcgaaaatt
    30841 accccttgca gtttcattca ccctcctgat gcgtggtagc ggtcccattg aagggcaaaa
    30901 taaaatcccc caaacagaaa acagattctt cagcgacgta aataagctga ccgttcaaac
    30961 gcagtgaaac aggcgcagaa gttcgaatcg caatacgctg cgcgtcgaga gtgacctgta
    31021 attcgcagcc ctgccagaac agagggaaag acaactgttg ccactgctca ggtaacgccg
    31081 gattgagatg taattcaccg tcacgcacgc tcaccccggc aaaaccctga atcgccccca
    31141 gccagatagc gccagttgcg gcagcgtgga taccgtcatc acagctatgc ggatcagcac
    31201 caagatcgat ttcagtcccc tcgcgccaga actgataact ttgggtcagc aggccacagc
    31261 gtgcggcaac aatgccgtgg attgctttac ttaatgacga gtcgtgaata gtgcgcggtt
    31321 cataaaattg cagattggca agacacgatg ccgctgagaa ctgctccggc agcatgtaat
    31381 tgagcatcac cacatcagct tgtttgagga tctgcatctc gttcacttct gcgcgtgaat
    31441 aatccagcag aatggtttgc ttccccgccg ccgctttgta tttcgccaga ttaatcaccg
    31501 gcttagccat aaacgaatca tcctgcggca aaacgccgtc gggctgaatt tctggcagcc
    31561 gcagttcttt gaggtacatt tctgcacgat gaataaacgc gtcgtcgcta cagccaaact
    31621 gacgagcgat attcagcgcc tgctggacgt tgtaatacgc catatagctg gtgaaggcgt
    31681 tattattgac atgttcggta tattcgtctg gcccaataac atcatgaatt tccagacgct
    31741 cgttaaccct caccgcgcgg ctaatccaga actttgccgt ctccagaagt agcgccatgc
    31801 cttcatgagc aatgaaactt tcatcccccg tggtccgcca gtattgaatc accgcccagg
    31861 cgatatcggc gaccagatgg tgttccgcct gcgcagaggc cactttttgc cgcagcccgg
    31921 tacgaatgtt aatggcggca aattccggcg tctcttcttc gccgctacgc gcgctttccc
    31981 acggaaacag agcgccctgc cagccgttgc gtcgcgcttt ctcctgcgcg ccaggcaagt
    32041 tgtgccagcg ataacgcagt aaacttcggg caaccgtcgg atcgctaaac agatggaacg
    32101 gtagcaaaaa tacttctgta tcccagaaaa cgtggccttt gtagccttcg ccggttaaac
    32161 ctttcgccgc aatgctgctg cgctcatcgt gggcaggcgt catgatgcgc aggtgataaa
    32221 gcgcataatc taatgcttgc tgatcgtgcg catcgcggcc gtttaccgtg atacgacgtt
    32281 tctgccacca ttgacgccag ttttctgttg atgctgcaag aagttggtcg taactctgct
    32341 gcgcgcacat ttcaagctga cgaagcgacg cactgcccca ttcgtctaaa gcggcttgtc
    32401 tgtcgtcccg ccagtcgatc cacaccagtt tttgcagcgt cagcgtctca cctgcgtgaa
    32461 gctgcgcgca ggtatgttgc aataaacggc gctctttggc ggtatagcat tgctgcacat
    32521 caccgctcac cttacagcaa cagctgatgg ccacatcact acgcccatcc tgggtggtgt
    32581 agatcccctg catcagatgc tgaccaaaca cccgcacctg gatttcgtca atatgctggc
    32641 gaccgtggtt ggtttgcgtg gcgtcaatgc ctgttgaaat cagcactgac gcgtcggcgt
    32701 ccagtggagt aatagtgatt tccagcgcaa tgagcggcag ttggtctgcc gaaacaaagc
    32761 gacggctggc gatggtgtaa ccagtgccgt tgctggtacg ccagacaacg ttgcgacgta
    32821 attcgccact ggcaaagtta agctcacgct gccatgcttc gcgggataac gagaaaatct
    32881 caccatttat ggcaatctcc atccccacga catcaggcag gttcaccagt tcgttgattt
    32941 ctcctttacc cgctcgatga tacagccccg ccagatacat cccacgggtc tggcgcgtgt
    33001 aatcttcttc atggctggca cgaagcccaa gatagccgtt cccctgcgcc atcagcgaag
    33061 catacttgtt cagggtatgc tggctgaaat ggggttctga taacgttact ggcctggtca
    33121 taattccaca cgcgtccctg tttccgcgga ttgatacaac gccgccacca gttgctggat
    33181 gatgtacccc tgctcggcgt cggctatcat cacgggcttg ccctgtacgt gattgataaa
    33241 ggcttccatg ctgcgcaaat ggcggttgtc gtctgccatt tcccgttgca tcagcgtcat
    33301 taattcaccg ttgttatcgg tgtagatatg tgccggaaac agcgtcgcac cggctttatc
    33361 accacaaaag ctgacattca taatcgactg ttcgcggatg ttgagtgcaa atgacgtttc
    33421 cagccacaga atgccgccgt tatgaaattc aatggtgcca aacagcgaat cttcaacgct
    33481 gtaagttgcc gggtcccact cgccaaattg accacagctc ttttgcgtgc cgatcttttg
    33541 aaagctatgc gcattcacgc ttttcaccgc cggaaagccc agcacataca tcgcagcatc
    33601 cagcatatga atgccgatgt cgatcagcgg gccaccaccc tgcagttctt tattggtaaa
    33661 gacaccccag ccgggaacgc cgctgcgacg cagggcgcgg gcggtggtaa cgtaaatctc
    33721 tcccaaaacg ccgttggtca cctgttcacg cagctgttgc gtatcgaacg caaaacgatg
    33781 gtgaaagtcg taggccagca ccttgccctg tttgcgcgcg gtatcgcaca tttcccgcgc
    33841 ctgttctgcc gtcatggcgg gcggtttttc gcacatcaca tggcagcccg cttcaagcgc
    33901 catcagggta tgttcgtaat gaaaacggtt cggtgagcag acgctaacca catcaggttt
    33961 caccgccagc agcatggcct gcggatcgtc ccacaaggat gcattaccgt atttttctgc
    34021 cagcgcctgc gcctgggaaa ggcggctgtc acagacggcc accagttcca gatcgttgcg
    34081 ggtgcagtag tacgaagcat gaaccttatc cgccacctgg cctgcgccga ttatcgcgac
    34141 acgcagcgga gagcttgtca ttgcactttt cacaaagacc tcttagcagg tgcgcaacca
    34201 ggccaacgaa tcacggtacg cctgggcagg agcttctgcc cggatacgcc cttcatacac
    34261 cacataaccc tgatagttat cggcgcgcag ctgttcaaac agcgcgtgga aatcgagggt
    34321 gccgctgccc ggctggtaac gatggttatc ggcaatatgc acatgaccga gcaagtcgcg
    34381 gtggtcatgc agcgcctgcg ccaggttatc ttcttcgatg ttcatgtgat agaaatcgcc
    34441 gataatctgc acatgtttaa gatcgttttc gacgatgtaa cggcgggcat cggcgagagt
    34501 attgatcata tgatcctgat aacggtttaa cggttcgaga tacaccacgg ttccggtacg
    34561 cgcggcgacc tgttccagta cgcgcaggga atcactcacc attttgcggt cgccgtccag
    34621 gctgcgcggc gaggtcatcg gcggtaaacg gaaggtaaac atgccccatg cagcaggaac
    34681 gacgatacct ttaccgccca cttctgccag cgcttcgaga atgcgttcga tctgctttaa
    34741 gccattaaga cgacgctctt cgataaaatc accaatccag ccgtcatagc cgccgcaggc
    34801 agtggtcacc ggtaaaccgg tttctttgat cgccgctttg acttcttcga tgttgttgac
    34861 cagcagtttg ccgtcaatct caaaaccatc gaagcccatc tctttgatgt aacgaaattt
    34921 ctccagaata tttcccggaa agaatgcctg attctgtgtg cctattttca ttttttcatt
    34981 cctttgaatt aaaacgtaac gcccattttg atgctctgtt ccggatgctg atcgacatac
    35041 tgcatgtagc tttccgggct gttggcaaag gtcactaccg ggtcgattaa atcttcgcaa
    35101 ttgagataac cgttcatcag cagttcccag caggtttctt caatacgctt acggctccag
    35161 cgcggataat ccgggttcgg ttcgctgcac gcgcgggaga aaacaatttt ggcgttattg
    35221 aaatgcgctt cgcgtccgag gttaaaacct tcagcaaatg gtttggcaaa cgcgacatag
    35281 gagatggtgc cgccgtaggc cagaccgcgg agcgccgact gcagcgcgtc ggcgtagccg
    35341 ctggtttcga taatcacatc ggcaccctgc ttgccggtca gcgttttgat ctctttacct
    35401 acgtcagcgc caatggggtt aagacagaaa tccgcaccgt ggcgacgggc aatatcacag
    35461 cgatgagcga taggatcgac accaatcacc accgacgcgc cagcgcgttt tgccagttga
    35521 atggcaattt gaccaatcgc gccaagccct accaccacca caaaatcgcc cacgcgcacg
    35581 ttggcatcgc gcacgccgct catggcaaac tgcgccgggt cgtaacagac ggcgtttttc
    35641 caggagctgc cttgcggcat tttgcgcagc ttgtagttat tcactgcgtt aatgatgacc
    35701 gtctcggaga gcgggccgta gccgcatacg ctgtcgccca ccgcgtagtc gttaacgtcg
    35761 ctgccgcact cgataatgtc gccaaccacc atgttgccaa gctggaactt gccaaactca
    35821 atgccgcgcg gcgcatttgc cggacgcggg ctgaacatct gccattcacc gttaaagtct
    35881 tcatcgataa acggactggc agcgcggaaa tcgaccactt ccgtcccgtg cttcggagcg
    35941 ccgaaacgca cgcggatctt cacttcattg gctaaaatcg cccgctcttc atactcaacc
    36001 agcgcagcta cacgcggtgc tgtggctact aactttttca tgtaaaactc cttgtaaaga
    36061 aattggtcgc tttagccctt cacgccacca gcggtcaaac cactcttaat aaaacgttcc
    36121 gaaagcgcat acataatcac taccggtagt gcggtcacca gcgaggccgc catcatccgt
    36181 ccccagatgt aatcaggcgt actgaacagc gcgttcaggc ccacaggtaa ggtgaaattg
    36241 ctggcgctgg aaaggaaaat cgacgcaaac agatagtcgt tccacgccac cataaagcag
    36301 tagacgaata cggatatcag cccggacatt gccaggggca cggtgatacg gaagataatt
    36361 tgcagacgat tgaggccatc catcattgcc gcttcttcga tttcatcggg gatggtgtcg
    36421 aagtagcttt tcagcataaa cacggcggta ggcagagttt gcgtcaccat ggtgataatc
    36481 agcgccatct cggtgtcgta aatgccaagt gcggtgatga ttttgaacag cggcaccacc
    36541 agcaaaatgc cggagaacat gtacaccgtg taaaagctgg cgttgatggt cattcgccct
    36601 ttaaagcgca ggcgggaaag cgcgtaagcc ccaagaatgc cgagaaatac cgccaccacg
    36661 gatgaaacca ccgacaccac catgctgtta cggaagtagt cgacaaacgg gaaaatcacc
    36721 ggattaaaaa tgtcgacgta atgctccagc gtccactgct gtggcagcaa cgtaggatgc
    36781 agcgagatcg cctcttttgc gctcttgaac gaggtcatca gcatcacaaa aaatggaaac
    36841 agcgtgatga tgagaaacag cgccagcccg cagtaaaaac cgattcgact gagtgtgcgt
    36901 ttatttgttg ccattgaggt tcacccgttt cctggtcagc agaatgacag cgaaaataat
    36961 gatgaaaagc accaccgaga tcgccgccgc tttccctaag tcattaaagg caaaggcggt
    37021 tttgtagaga tagacaccga gaatatcgac cttggtcgtc agcagataaa catccgcgaa
    37081 catgtagaac atccagatag tgcgcagggt caccaccgtc gccagaaccg gcataatcgc
    37141 gggcagcgtg acgatgcgaa accgttgcca ggcattcgcg ccatccatct ctgccgcttc
    37201 gtacagcgat ttgtcgatgg tctgcaaaat cgccagaaac gagataaagg catacgggaa
    37261 gtagcgccag atggcgaaca gcaccaccag cacaaaacta ctgcccgggt tatcgaacca
    37321 cagcggcgcc tgctcataga gatgcagaag atcgacgccg aggtagttca caatgccgta
    37381 gccgttgttg aacatgtatt tccaggcgaa caccagcgaa atagacggcg ttacgtagga
    37441 aaggatcacc agcgaacgcg cggttttgcg caggcggaac tcgcggttga aaaacatcgc
    37501 cacggccagc ccgagcacgg tgctgcccgc caccacaagc gcggtatacc agaccgtcat
    37561 ccacagcgag tgccagaaac caggatcgga gagaatgcgc acatagttac tcaccccaac
    37621 aaacgttgac tcgatgttgg gattaagcgg cagacgtaaa aaactgattt cgatattcga
    37681 caccatcggc cacgccacca gaccgcccag cagtaataag ctgggcgcga gaagcaacag
    37741 cgcaaagggc atatcggaac gacctgaaaa aagcctgttc attgcggatt cctgtcctgg
    37801 gtttagcgct gttcgaccaa ctcatccagc tttttctggc tcgcttgcag cgtgccaggg
    37861 aggtcggctt tacccacggt gacgttatgc accattgaac tcaccacacc agaccccgtc
    37921 acatcaccca tgcgggtaaa gtttttatcc cctactgcgc caaagacctg aatatttggc
    37981 aattcgctga ttagctgatt cggcaattct cccagcgcct taataacgtc gttgtctttc
    38041 caggtggcgg tagtgacaac cgctttgttc accggcagcg ccgcgcctgg tgacatcatc
    38101 acccagtcgg caatgttgtc cgcctgctcc ataaaggtga caaatttttc agccgcttcg
    38161 gtctcttcag tcttttgccc ggcggtaatg gtcagcgagg tcaacatgcc gtagaccgca
    38221 gaatttttct cggttggcac cacgaaacca acgtttttcg gatcgccttc tttaatcaca
    38281 gccggaagga tataggtgga gtaaatcgcc atcggcgcgg tgccgttcat aaaagcgtct
    38341 ttcacttcca tgatgtcgtt agaacctggc atggtgttgg cagcaaggtt gcggtaatag
    38401 gtcagcgcct gcatcatctc tggtgtatca agggtgattt tgccttcggc gttaaagacg
    38461 ttagcctgat tggataacgc aaactgggag aaagactgtt ccgtcaacac gctttctgct
    38521 gtaggcagcg caataccgta ttttttattc gccgggtcat tcagtttctg tgcaacgtcc
    38581 agcaattgct gccagttttt tggctcctcc agcccagctt ttgccagcac atctttgcga
    38641 taccagatcc cgccaatcca tgcgctgaca ggaacaccgg tccaggcgct gccatcttcg
    38701 gtgcgcacaa tccgcagtac gccatcgtag aacgcgcctt caccgacgtt gctgatgacc
    38761 gtggcaaccg ctttacgatc gataagctgc tctttgtcca tcactttggc gtagtcatgg
    38821 ctggtttcga tcacttccgg cagcgaaccg ctacgtgaaa gggtaatgac tttggtgtta
    38881 taggcgtctt cttccacggg cacttgtttt acggtgatac ctgggttttc tttttcaaaa
    38941 cgggcaatca atttgctgat gacggcctgg cgctcctgct ccaccgaaga atgcataaat
    39001 tcgatggata cattattttt attttcttct ttacagcctg aaatcagggc gcaggaaacc
    39061 agtgctgata acagcacgat ttttgattta atcatgaaat gttccttttt atttaatcca
    39121 cataacctgc cagggatgca gtgttatttc attacccaat atatcaactt cactaatcag
    39181 atcccgaccg tgcaggtcag taatatttat atgctgaata ttttcgctga cattaaacaa
    39241 tcccgtcagg caatcgccat ccgcattgct tctttgaatt cgcattacaa atgaattaat
    39301 tgcatcgatg gtgaaattat tatccggatg aaactcttta tgactgcgac gaagggtaat
    39361 taaatgcgac aacttataat ataccgaata ccttaatgtc gctttattgt ccagttctgt
    39421 cgttatctct ttactagagt attttttacg gttaatcgcg cgattatatc caagtttttc
    39481 gacaccggcg taatcattac gcgaccccag aatgctttga atatatatcg ctggcacacc
    39541 ggggaaactt aacaaaatcg catgggcgag aataaacctg gcacaccgtt cttcgtcgct
    39601 acactcacgg cggctcaacg catccatata ggtgacattc atttcatagg ggctacgcgt
    39661 accgtcggga ttatttttcc agtttactaa tgccccttcc tgctgtaaca cctcgaccag
    39721 cgctaatatt tcgttttcgg gtaacaaccc ccgcagtggg ttaagcccga tgccatcgtg
    39781 agaggcaagg aagttaaacc aggtggtgtt gctggaaggt agtgtcaggt tttgcgccca
    39841 cgcacaaagt gcctcaacgt tctgtttttg caccgcatgc agcaccagcg gcggcagcga
    39901 gaactggtac accatatgcg cttcgtcatc gccttcgcca aagtaagcaa tgttgtcttt
    39961 atgcggaaca ttggtctcgg taatgatcac tgtgcctggc gcgacgttat caataatcga
    40021 acgtaacagt ttgataatca gatgtgtttt ttccagatgg atgcagtttg ttcccggctc
    40081 tttccacata aagccaacgg catccagacg gacatactct gcgccctttt ccaggtagca
    40141 cagcaataca tccaccatcg ccagcaacac ttcagggcta cggtaattga ggtcaatttg
    40201 atcgtcgcta aaggtggtcc ataaatgacg cgttgaatga tcgcgcatct ggaatggcgt
    40261 taataacggt aacgcacgcg ggcgagtgac ggcgctgaga tcggttttcg gatcaacggt
    40321 aataaaaaaa tcttcaaaac ctggctgctg ttgtaaatag tttttaaacc attcactttt
    40381 tgccgacata tggttgcaga caaaatcaaa cattaaatgg ctgcattcac cgagttgctg
    40441 aatatcctgc cactcccccg cttcactggc gacctgatga taatcaatta ccgaaaatcc
    40501 atcatcagat gaccatggat aaaaaggtaa taaatgaaca tgtgaaaaaa ttctttgcag
    40561 ccattgaggg taaaactgat taaatgtggg tagtggcttt aaatcattac tgtgaaattg
    40621 atcggcatag gtaattaaca cgacatcact ttcatcccag tgttttttac gtcgctgtgt
    40681 aattaatcgt ttcgcactct caagacgcgt tacaagtttc tgtaaatgag tcgcggtaaa
    40741 tgttccaccg tagatttcgt ccaggtaatc cgtaattttc tgttgcatgt tgcctttccg
    40801 tggtagcggt cccatgaagc gagagactac tccgcataaa ataaactgtc aattgagctc
    40861 aaggggttta gtcacgcagg aaatcttttt ttacctggga aaaagcgtat ttgtgagctg
    40921 acgcaaataa tctatgggga tgtaaataag gtgtgacaga aaaaaacggc gcataagcgc
    40981 cgctcatggt gaattctttt aacctttgac cttcggcatt gcgatgtctt tcaggccacc
    41041 ggcgttctca acgtgggtat atcccatctc gctaaggatc tcttttgcct gccctgactg
    41101 gcgtccggca ttgcaataca ctttcacggt gtcgttttta tccggaacgg cggtagcaat
    41161 gcgctctttc acttccttca ggggaatatt gatggccccc tgaacgtgct cttgctgata
    41221 ctgctctgga acacgaacat cgatccagtg ttcagcggcg aaaacgggca gtgaaaacac
    41281 cagtgtcaga gcaagtaagc cttttttaaa catgtaagcg tccttctatg gatgaaaatt
    41341 gctatccatt atacgcctga gatttaacca tttttgcgaa actcccctca ccttttataa
    41401 cgctgcgcca gtttattggc agcccgactt aacagcggtt ccagcgccac agccagcaac
    41461 attttcagcg gtcggcgagc aactgatttt atcgcccagc ccgccacacc cgccgggcca
    41521 tagcgcagtg cggtaagaag taccagcttg cctgctaatt tgaacccagg cttcaccttt
    41581 tgcccggcct gttgccagcg agtattcata actttcctca cagttgacgg aaacggctac
    41641 gcagcgtgaa agtgtcggaa gtgacataac gttccatctc gcgtaaacgc gtttcacttg
    41701 ccgccagttc acggtcgact tcatccagca attcgctgct ggaaggtagc tgctcaccaa
    41761 aggccatgtt gtccggcatt ggatcaagcg caaatgacaa aatgatgtaa gcaaccaggg
    41821 taaacagcgc cagaccgaag aaaatcgaca gcaccaccag gatacgcacc agttttactg
    41881 gtacatcaaa atagttggca atcccggcgc agacgccacg gaccatgccc tgctgcggaa
    41941 tacgccataa ttttttattg agattaatgc ccgccattag cgatccctcc agttcggatg
    42001 ttctgcatca agaatggatt ccagcgcctg aatacgctcg cgcatccgtt ttgcttcatc
    42061 agccagttgc gctaatcgct gctgctcact ttgtgacaat tcactgcgac cggaacgatt
    42121 gctgtaatgc agccataacc agatcggtaa aacaaacagc acaaaaatgg ttaacggaat
    42181 agccagaaat agcgcgctca taagtactcc ttagacgatg agcggcggcg cgttcggacg
    42241 ccgcctggat gttattattg attgtcttgc ttcattttgg cttttaattg tgccagttgc
    42301 tcgctgattg catcatcggc tttcagttcg gcaaactgat cgtccagcga tttttgttta
    42361 ccgaagctgt ggctttctgc ttccgcttcc atctggtcga tacggcgttc gaaagattcg
    42421 aaacgagcca ttgcttcatc cagtttgcca ctgtccagct gacgacgcac atcgcgcgac
    42481 gagtttgccg cttgatggcg taacatcaat gcctgctggc gagcgcgtgt ttcgctcaat
    42541 ttgttttcca gctcgccgat ctctttcttc atacgcacta gcgtatcgtc caccagcgtc
    42601 acttcatgtt ccaggctctt aatcagatcg gtcagtttct gtttttcaat taacgccgca
    42661 cgcgccagat cctctctctc tttcagcagt gccagttccg ctttttcctg ccattcaatt
    42721 tcacgagccg acgcttgttc aatacggcga gtcagctgtt tcttttctgc cagcgcacgc
    42781 gccgaagtag aacgtacttc aaccaatgta tcttccatct cctggatcat cagacgcacc
    42841 agtttctgtg gatcttccgc tttctctaac agagcgttga tgttggcatt cacgatgtcg
    42901 gcaaagcgag aaaaaatacc cataatgttg tcctcttgat ttctgcgttc aggattgtcc
    42961 tgctgaactg ttaatacaat ttgcgtgcca attttttatc tttttgattt ataaagatct
    43021 gattgaagaa tcaacagcaa catgccagga tgaattagcg aattacacta acaagtggcg
    43081 aatttcatca tggcagaata caaagataat ttactcggtg aggcgaacag ctttctcgaa
    43141 gtgctggaac aggtttcgca tctcgcaccg ctggacaaac cggtgctcat catcggcgag
    43201 cgcggcaccg gtaaagagct gattgccagc cgtctgcatt atctctcctc ccgttggcaa
    43261 gggccgttta tttcccttaa ctgcgcggcg ttaaatgaaa atttgctgga ttccgaactg
    43321 tttggtcacg aagcgggggc gtttaccggt gcgcaaaaac gtcatccagg gagatttgaa
    43381 cgtgccgacg gcggtacgct atttcttgat gaactcgcta cggcaccgat gatggtgcag
    43441 gaaaaattat tgcgtgtgat tgagtacggt gaactggagc gcgtcggcgg cagccagcca
    43501 ttgcaggtga atgtgcggtt ggtatgcgcg acgaatgccg atctcccggc aatggtcaat
    43561 gaagggactt ttcgcgctga cctgctcgac cgactagcgt tcgatgttgt gcaactgccg
    43621 ccactacgcg aacgtgaaag cgacattatg ttgatggcag aacactttgc catccagatg
    43681 tgtcgggaaa tcaagctgcc tctgttcccg ggttttaccg agcacgccag agaaacattg
    43741 ctgaattatc gctggccggg aaatatacgt gaattgaaaa acgtggtgga acgttcagtg
    43801 tatcgccacg gcaccagcga ttatccgctt gatgacatca ttattgatcc ctttaaacgc
    43861 cgtccatctg aagaagccat cgccgtttca gaaaacacct cgcttccgac gctgccgctg
    43921 gatttacgcg agtttcagat gcagcaggaa aaagaactgc ttcaggtcag cttggaacaa
    43981 gggaagtata accagaagcg cgccgctgaa ttgctggggt taacctatca tcagttccgc
    44041 gcgttgctga aaaagcacca gctttagcat ttcgacaatg caacttgccg ggtgtgccgt
    44101 gaacgcctta tcaggcctac aaaatcaata cgtcgtttgc aggcctgata agcgctgcgc
    44161 atcaggcatt attgcgttaa ccctgcttct gcgtattaat ctctcagcgc atcctgcaaa
    44221 attttcattg ccgcatcgaa ttgcgcaacc gggatggtat gggcttcgtt aggcggcgca
    44281 tatttgtggt atttgatccg ccgctatcgc aaagtgccat tgtatgatgg cgacagaacg
    44341 ccggtgagcg aaacgtaata gtcgaatgcg cggcgcatta tcctgcctga gggtaatgca
    44401 ccgcgccatt aactataaaa atatgtatga cccggatcac gagtgctatc atccgccctt
    44461 atgcttagcg cattaacccc aggggcaaat aatgaaccac gatatcccgc taaaatatta
    44521 tgatattgcc gatgagtacg cgaccgaatg cgcagagcct gtcgcagacg ctgaacgcac
    44581 accgctggcc cactacttcc agttactgct cacccgtttg atgaacaatg aagagatcag
    44641 tgaagaagcc caacatgaaa tggctgctga agcggggatt aatcccgtac gcattgatga
    44701 gatcgcagag tttttgaatc aatggggtaa tgagtaatta tttaattgca gactatcggt
    44761 cagtatcgtt gcccggataa agcgttcgcg ccgcatccgg ctaaaaatga cacgcactgc
    44821 agcgtgcttt aatgggtttc tcacgatcgt accgctctgc tcctcgctaa gttgttctgt
    44881 gagttatagt tataaagaaa tcacgggtac gaatgttgaa ctgatggcga cgccacctgt
    44941 tcaatgacca accacacggc cctcattatt acctctgaac acaaacggta atggcaaatg
    45001 tcattaaata ttagtaagat agcctcttta cataaaatcc cttaatatta tgcgccaggt
    45061 attatcgtct cttttggtga ttgctggact tgtgagtggt caggcaatcg ccgcgcctga
    45121 atcccccccg catgctgata tccgcgacag cggttttgtc tattgcgtca gcgggcaagt
    45181 caacaccttt aacccatcca aagcgagcag tgggttaatt gtcgataccc ttgccgccca
    45241 gttttatgat cgactgctgg atgtcgatcc ctatacctat cgtctgatgc cggaacttgc
    45301 cgaaagctgg gaagtactcg acaacggcgc aacctatcgc ttccacctgc gtcgcgatgt
    45361 tccgtttcaa aaaaccgact ggtttactcc cactcgtaaa atgaatgccg acgatgtggt
    45421 ttttaccttc cagcgaattt ttgaccgcaa caacccgtgg cataacgtta atggcagcaa
    45481 cttcccctac ttcgacagcc tgcaatttgc cgataacgtg aaaagcgtcc gcaaactgga
    45541 taatcatacc gttgagttcc gtctggctca gccggatgct tcttttttgt ggcacctcgc
    45601 gacccattat gcttcggtca tgtcggcaga atatgcaggg aagttagaga aagaagatcg
    45661 ccaggagcaa ctcgaccgtc aaccggtcgg caccggtccg tatcagttgt cggaataccg
    45721 cgccgggcaa tatattcgct tacaacgtca tgatgatttc tggcgtggta agccgttgat
    45781 gccacaagtg gtggtggatt taggctctgg cggtacagga cgattgtcga aactcctgac
    45841 cggggagtgc gacgttctgg cctggcctgc tgccagtcag ctatccattt tgcgtgacga
    45901 cccacgcttg cgtttaacgc tgcgtcctgg gatgaacgtc gcctatctgg cattcaacac
    45961 cgccaaaccg ccgctaaata atcccgctgt ccgccatgcg ctggcactgg caattaataa
    46021 ccagcgcctg atgcaatcca tctattatgg tacggctgaa acagcggcct ctattttacc
    46081 gcgcgcctcg tgggcctatg acaacgaggc taaaattact gaatacaatc cggcaaaatc
    46141 gcgcgaacag ttgaaggcgt tggggctgga aaacttaacg ctgaaactgt gggtgcccac
    46201 acgttcgcag gcgtggaacc ccagtccact gaaaaccgcc gaactgattc aggcggatat
    46261 ggcacaggtt ggcgtaaaag tggtgattgt gccggtagaa ggtcgttttc aggaggcgcg
    46321 gttgatggat atgagccatg atctgacgtt atccggttgg gcgacggaca gtaacgaccc
    46381 ggacagtttc ttccgtccgt tactgagctg cgcggcaatt cattcgcaga ccaacctcgc
    46441 ccactggtgc gatccgaaat tcgacagcgt gttgcgtaag gcgctctcct cgcagcagct
    46501 ggcggcgcgt attgaagcct atgacgaagc gcaaagtatt ctggcgcagg aattacctat
    46561 tctgccgctg gcgtcgtcat tgcgtttgca ggcctatcgg tacgatatca aaggtctggt
    46621 acttagcccg tttggtaacg cctcctttgc tggggtgtat cgcgagaaac aggatgaggt
    46681 gaaaaagcca tgattatctt caccttacgc cgtattttgt tattgattgt gaccttgttc
    46741 ctgctgacct tcgttggctt cagcttgagc tatttcaccc cacatgcgcc gttacaaggc
    46801 gcgtcactgt ggaatgcctg ggtgttctgg tttaatggcc tgatccactg ggattttggt
    46861 gtttccagca ttaacggtca accgattgcc gaacagttaa aagaggtctt cccggcaacg
    46921 atggaactgt gcatcctcgc cttcggtttt gcgctgattg ttggcatccc cgtggggatg
    46981 attgccggga ttacgcgcca taagtggcag gataacttga tcaacgccat cgccttactg
    47041 ggcttttcaa tcccggtgtt ctggctggcg cttctgttga cgctgttttg ttcactcacg
    47101 ctaggttggt tgcccgtttc agggcgtttc gatctgctct acgaagtgaa accgattacc
    47161 ggttttgcgt tgattgatgc ctggctttcg gactcaccgt ggcgggatga aatgatcatt
    47221 agcgcaatcc gccatatggt attgcccgtg atcaccctgt cggttgcgcc aacaactgaa
    47281 gtgatccgac tgatgcgtat cagcactatc gaagtgtatg accagaacta tgttaaagca
    47341 gcggcgaccc gcggtttgtc gcgctttact attttgcgtc gccacgttct gcataacgcg
    47401 ttacctccgg ttattcctcg cctgggctta cagttttcca ccatgctgac gctggcgatg
    47461 atcaccgaaa tggtttttag ctggccgggt ttagggcgct ggttaattaa cgccatccgc
    47521 cagcaggatt acgcagccat ttccgccgga gtgatggtgt gtggctcact ggtcattatt
    47581 gttaacgtga tttctgatat tttgggtgcc atggctaacc ctctgaaaca taaggaatgg
    47641 tatgccttac gatagcgtat acagcgaaaa gcgcccgccg ggcacgctgc gtaccgcctg
    47701 gcgcaaattt tatagtgacg cctctgcgat ggtcggcctg tacggctgcg cggggctggc
    47761 tgtactgtgt atttttggcg gctggtttgc gccttacggc atcgaccagc aatttctcgg
    47821 ttatcaatta ttgccgccgt catggtcgcg ctatggcgaa gtttctttct tcctggggac
    47881 tgacgacctc ggacgcgatg ttttaagccg tttactgagc ggagctgcgc caaccgtagg
    47941 tggcgcattt gtggtgacgc ttgccgcgac gatctgtggc ctggtactgg gcaccttcgc
    48001 cggggcgacc cacggcctac gctcagcggt gcttaaccat attctggata ccttactggc
    48061 gatcccttcg ctgctgctgg caattatcgt tgtagcgttt gccggaccga gtttgtctca
    48121 cgccatgttt gctgtctggc tggcgctgct gccacgtatg gtacgttcga tttacagcat
    48181 ggtgcatgac gaactggaaa aagagtacgt tatcgccgcc cgtctggatg gcgcatcaac
    48241 gctgaatatt ctctggtttg ctgtgatgcc caacatcacc gccgggctgg tcaccgagat
    48301 cacccgcgca ctgtcgatgg caattctcga tatcgccgcg ctgggctttc tcgatctcgg
    48361 cgcacaactg ccctcgcctg aatggggagc gatgctcggt gatgcgctgg aactgattta
    48421 tgtcgccccg tggactgtca tgctgcctgg tgcggcgatt atgattagcg tgctgttggt
    48481 taacctcctt ggcgacggtg tccgtcgtgc aattattgcg ggggtggaat aatgccatta
    48541 ctcgatattc gtaacctgac cattgaattt aaaaccggtg atgagtgggt taaagccgtc
    48601 gaccgcgtaa gtatgacctt aaccgaaggt gaaatccgcg gtcttgttgg cgaatccggt
    48661 tccggtaaaa gtttgattgc gaaagcgatt tgtggggtga ataaagataa ctggcgtgtt
    48721 actgctgacc gtatgcgttt tgatgatatc gatttgctgc gtctctccgc acgcgaacgg
    48781 cgcaagctgg ttggtcacaa cgtgtcgatg attttccagg aaccgcagtc gtgtcttgac
    48841 ccttcagaac gtgtgggtcg ccagttgatg caaaacatcc cagcctggac ctataaaggc
    48901 cgttggtggc agcgttttgg ctggcgcaaa cgccgtgcca ttgaactgct gcaccgcgtg
    48961 gggattaaag atcacaaaga tgcgatgcgc agttttccct atgagttgac cgaaggcgaa
    49021 tgtcagaaag tgatgatagc cattgcactg gcgaatcaac cgcgtctgct gattgctgac
    49081 gaaccgacaa actcaatgga gccaacaacc caggcgcaaa tctttcgcct cctgacgcgt
    49141 ctcaaccaaa acagcaatac cactattttg cttatcagcc atgacttaca aatgcttagc
    49201 caatgggcgg ataaaattaa cgtgctttac tgcggtcaaa cggtggaaac cgcgccgagt
    49261 aaggagttgg tgacgatgcc acaccatcct tatacccagg cgctgatccg cgcgatacca
    49321 gacttcggca gcgcgatgcc gcataaaagt cgcctcaata cgctgcccgg cgctatcccg
    49381 ctactggaac agttaccgat tggttgtcgt ctggggccac gttgcccgta tgcacaacga
    49441 gaatgcattg tgacgccacg tttgacgggg gcgaaaaatc atctctatgc ctgtcatttc
    49501 ccactgaaca tggagaaaga gtgagatgat cgaaacgcta cttgaagtgc gtaatttaag
    49561 taaaacgttc cgctaccgga ccggctggtt tcgtcgtcag accgtagaag cggtaaaacc
    49621 cttgagcttt acgctacgtg aaggccagac actggcgatt atcggcgaga atggttcggg
    49681 taaatccacg ctggcaaaaa tgctggcggg aatgatagaa cctaccagcg gcgagttatt
    49741 gattgacgat catccgctgc attttggcga ttattccttc cgcagtcagc gtattcgcat
    49801 gatttttcag gatccttcca cctcgttgaa tccccgtcaa cgtatctcgc aaattctgga
    49861 ttttccactg cgcctgaaca ccgacctgga accggaacag cgtcgcaaac agattattga
    49921 aacgatgcgt atggttgggc tgctaccgga tcacgtcagt tactatccgc atatgttggc
    49981 acccgggcaa aaacagcgtc tgggtctggc gcgcgcgctg atattgcgcc caaaagtcat
    50041 tattgccgat gaagccctcg cctcactgga tatgtcgatg cgttcgcagt tgattaatct
    50101 gatgctggag ttacaggaaa aacagggcat ttcgtatatt tatgttaccc agcatatcgg
    50161 aatgatgaag cacattagcg accaggtgct ggtgatgcat cagggcgagg ttgtcgagcg
    50221 aggcagcacc gcagatgtgc tggcatcgcc gctgcatgaa ctcaccaaac ggctgatcgc
    50281 cggtcatttt ggcgaggcat tgacggcgga tgcgtggcgt aaggaccgtt agtgttttgc
    50341 acctcatcct gacaggcccc cctcaggatg aggtgttcat tacttttggt tgtcgattct
    50401 ggtgagagca accagcaatg ccagcgtata acacaccgta attgccagac tcatttttaa
    50461 cagtgtttct ccgccaattc ccgacaatgg cgcggctata ccgccgaaga caaacatgct
    50521 catccccatc aacgcagacg ccgttccaga ttcctgcgtc cctactgcac tcatagcctc
    50581 tgccccgcca acagtgccga tgccgctaca aaatgcgatg gtgaaaaata atgccaccag
    50641 tgccggaatg ggcaattgta tccatgcgca taagaccgtg agcaatgcac acaaaattgc
    50701 cgctatcagg ccacctcgca acaatgtcat cgcgttaatc cgtcgcgcca ggcgcgagaa
    50761 gatccatgaa gcaatgataa gtccggtgcc gttaaggcca aacaccaggc taaattgcat
    50821 tggactaaag ccaaattcct tctgcaacac gaacgacgaa gagccgatat atgcaaacaa
    50881 accggccagc ataaaacttt gaatcaggca aaagcgcata aaacggcggt tctgcaccac
    50941 gcttcgtccg gttaatagca atgatgagcc ccttttattt tctggcaagg tctcatgaat
    51001 aaataacaga cagcccagca acagtacggt gctaatttca gccattaccc agaataaagt
    51061 gcgccagtca aaagtgctaa caatgtaccc gcccagcact ggcgacaaca ccggtgccag
    51121 gccattcacc gtcattaaca gcgcaaaaaa ctgggtcaac gttactccct gatatttgtc
    51181 acgagcaata gaacgagaga gcaccgaacc acccgccccc gcgatccctt gaataaaacg
    51241 ccagaccacc agccagtaaa tattgttcgt tgtcgcgcat aaaatggaag aaacaataaa
    51301 caatagcaac gacaagatta acggacgttt acgccctatt ttgtcgctca gagggccaaa
    51361 taacagttgt ccgacgccaa gaccaatcag tgatgcggtc agggttaatt gcgttatggt
    51421 cgtggttgcc gccagttgct cagacatctc cggcaaagcc ggcaaataaa gatcggtaca
    51481 catcgggccg ataccggcta aaagaccaag aatcaatgcc catgaaagag agactctagc
    51541 catattattc cttacttgag tgatgacata ccgccgccca gcgactgcca gagcgtgatt
    51601 cggtttgtaa aatcagtcag ttgcagtgcc agcagctcct gctgtgcgct ccacaagctg
    51661 cgctgcgccg tcaacacggt caggtaatca ccaacacccg cctgatagcg acgcaagcca
    51721 acatcgaccg tttgttgttc agctttaaca tactggcgct gtgcatccag ttgctcttca
    51781 agcgtggtcc gccgcgccag tgcgttagcg acatctttaa atgcgctctg aacggttttt
    51841 tcataggtgg caatgagtcc acgcttttgt gcttctgcgt aacgaagctg cgccagatta
    51901 cttccgccag taaacagcgg taatgtgacc gatggcgcaa atgaccagat ctgcattccg
    51961 tggctgaaca acgacgacaa cgcgtcactg ccaacaccgg cactggcagt cagcgaaatc
    52021 gtcgggaaaa agttagcccg cgccgcgcca atatctgcat tggcgctctt caaattatgt
    52081 tccgcttcct ggatatccgg gcgacgcagc agaacatcag atgatactcc cgcaggaacc
    52141 agacttatca tttgttccgg caggctttcc agtgttcccg gtagcagatt ttccgcaagc
    52201 gttgtacctg ccagtaagtt cagcgcattt ttatcctgca tcacttgtgt ctgatagctg
    52261 gcaacgctgg cgcgcgcttg ctgataaaca ctcatcgcct cactgacatc tgtcgctgcc
    52321 gccgtgccaa cctgttgctg gcgctggata attttcaatg agttttctgc actggccatc
    52381 gtttcttttg ccagggccag gttgctgtta tcagccgcca gtgtcagcca ggcggtgctg
    52441 atttcagcaa tcagcgttaa acgagtgttc tgggctgtaa attcactggc aagccaggtt
    52501 tcccgcgccg cccgagataa actctgatta cgaccaaaca gatctaacgt ataactggac
    52561 accgtgccgt cagcctcggc agttgttccc gtaccattcg ccagcgaacg gctgcgggtc
    52621 gaacttaagg ccgcattcac cgtcggaaat aacgacgcat tagtttgccc atagagcgcc
    52681 cgtgctgagt caatatcagc aatcgctttt tgcacatcgc ggttactgtt cagtgcaatg
    52741 gttactacct gctgcaatcg gggatcgtgg atcacctgct gccagtcatg gctgattgcc
    52801 ttcccctggc cctgtgctcc cggcaaggtc gccgggattg gggattcagg cgtactgtag
    52861 tgaggatcga gcgagacaca tcccgcactc aacaacacca gaaaaataag agaacgacgc
    52921 aacataactt actcctgacg gcgcggttta ccggcaaaca aacgtttcac cagtacaaaa
    52981 aacagaggaa cgaagaaaat ggccagtaat gtagcggtca gcgtgccgcc aataatgccc
    53041 gtaccaatgg cgatgcggct gttcgcccct gcgccggttg ctatcgccag cggcattacc
    53101 cccgcaataa acgccagcga ggtcatgatg attgggcgta aacgagtctg cgccgcgcgt
    53161 aatgccgcac gactcaagga atagccctct gcaaccgccg cttcagcaaa ttccacaatc
    53221 agaatggcgt ttttcgacga caagccgata gtagttaata gcgctacctg gaagtaaacg
    53281 tcgttgttta aatcacgcat ccaggccgcc agcgccgcgc caagaagccc cagagggatc
    53341 accagaatga ccgagaacgg gactgaccag ctttcgtaca gtgctgcaag gcagaggaaa
    53401 accaccagaa tagaaactgc atacagactt aatgcctgac cgctggccag tttctcctgc
    53461 aatgacaaac cactccaggc ccaggttgtt cccgcaggaa gactgtttgc cagttcctcc
    53521 atttttgtca ttgcatcgcc ggaactaaag ccagtcgcgt tttcgccctg aatttcatag
    53581 gctgccgagc cgttgtagcg caccagtctt tccggtccat acagccagcg ggtggtcgca
    53641 aaagcagaga atggtgtcat ggcgttatcg ctgccgcgca caaaccattt acctaagtct
    53701 gacggcgcgg aacgaaattc gctgtcgccc tgaatgtaga cttttttcac acgaccacgg
    53761 tcaataaagt cattcacata agtaccgccc cacgcactgg acagggtgtc ggtgacatca
    53821 ttcaaactca accctaatga caccgcttta ttactatcaa tatctacctg caattgcggc
    53881 atttgtggca aatcattggc gcgtacagaa tgtaactccg gactttgatt cgctttttct
    53941 atcaactgat tacgcatttg cagcagtgtt tcacgatcgg ttccaccgtt agctaacaat
    54001 tcaaacgtaa aaccattgct ttggcccagc ccatcaacgg ctggcggcgt catcgcaaat
    54061 accgtggcat cacgaattgt gcccagctct ttggttgccc gtagggcgat agcctgggcg
    54121 gtgttttctg cccctttacg ttgagaccag tttttcaacg aaacaaacgc catcccggtg
    54181 ttctgtccgc taccgctaaa actgaaacca tcaacggtaa agatgacatc ggtatttgct
    54241 ttctcgttaa tcaggaacca gtcaacaatc tggcgattca cttctgctgt acgggcagcg
    54301 gtcgccccgg ccggcagcgt gtactgcacc atgatttcgc cctggtcttc agtgggtaag
    54361 aaactgcccg gcagtttcca catcatcagg gccattccac cacccagcac gacataaagc
    54421 cccatcgttc gggctgcacg gcgcaggaca taaattacgc ctcgctgata tttatcttca
    54481 gtacggcggt aaaagcggtt aaatgcgccg aaaaagcctt ttttatgtgg tggaacatgc
    54541 tggaggacgg aaccgcacag ggcgggagtc aaggtcaatg ccaccaccac ggaaagcagc
    54601 attgcggaga tgatggtgat ggagaactga cgataaatta cccccgtaga tcccccaaag
    54661 aaggccatcg gcaggaatac ggctgacaac accagcgcaa tggcaaccag tgcgccagaa
    54721 atctcgccca ttgatttttc cgtggcttca cgcgcgggca acccttcgtc acgcataatg
    54781 cgttcgacgt tctctaccac cacaatggca tcgtccacca gcaagccgat cgccagcacc
    54841 attgcaaaca acgtcagggt attaatcgaa tagccaaaca acgcaagaac gccgaatgtg
    54901 cccagcaaaa cgacggggac agctaacgcc ggaatcagtg tggcacgcag gttttgcagg
    54961 aataaataca tcacgcaaac caccaatacg atggcttcaa acagcgtctg aattacgtcc
    55021 tctacggaga ttttaataaa ttcagtgctg tctttcgggt atgcgatgtc gtatccctgc
    55081 ggcatgttcc gctggaattc ggcaatctta tccttgacca gcgtcgccgt attcagcgca
    55141 ttcgcaccgg gcgaaagcat tacagcaacc ccggcagacg ggtgaccgtt aagtttgccg
    55201 atagcggtat aatcttcact gcccatctca acgcgagcca catcttttat acgaacaact
    55261 gcgccgtctg actggctttt cacgataata tttttgaact gatccaccgt ctgcaagcga
    55321 gactgcgcac gtaccgttgc ggtcagttgc tgagtatccg gtgaaggcaa tgcccctatt
    55381 ttcccggcag taacctgcac gttttgcgct tcaatagcac tttgcacgtc tgaaggcatc
    55441 agcgagtaag acgccagttt ggccgggtca agccagatgc gcatagcgta ttccgcgcca
    55501 aagacttgca gactccccac accttcaaca cgcgccagcg ggtcctgaac gttactgacc
    55561 agccagtcgg cgatatccga actggaggct ttgtcagtgg tgtcatacac ggcagcaatc
    55621 agcaaaaagt tgctttgtga tttctccacc gtaacacccg tttgctgcac ttcgctgggt
    55681 aggcgcgact ccgcctgctg aattttattc tgcacctgaa cctgtgcagt atctggatcg
    55741 gtaccttgtt caaaggtcac attaatactg accgaaccat cagagctact ggttgagctg
    55801 aaatagagta aattatcaag cccagtgagt tgttgctcga taacctgagt cacgctgttc
    55861 tccagcgttt cggcagaagc accagtataa gtggctgaaa ttttaatggt cggcggtgca
    55921 acgtcaggat attgcgcgac gggcaatgtg cgaatagcca gaatccctgc caacataatc
    55981 aaaatggcga taacccaggc aaagaccggg cggcgaacaa aaaagcgcga aaacatcagg
    56041 cgttgcctcc attagcctga acttcaacag ccttgacggt ctgccctgaa gtgactttgg
    56101 cagaaccttc aacaatcagt cggtcgccgt tgtgcaggcc gttcagcacc agccatttat
    56161 caccatacgt ttctcccgtt tcgagcgttc gctgctctac tttattgtct ttattcacca
    56221 ccagcgcagt tgcattgcct ttagcatcgc gcgtaacgcc ctgttgaggc gcgagaatag
    56281 cgttttccat cacgccttca tcgacacgag cgcgaacaaa cattcccggt aataactgct
    56341 gttgtggatt ggggaaaatt gcccgtaatg tcaccgaacc ggtagactca tccaccgcga
    56401 cttcggtgag ttccagacgc cctttttcgc tgtaggttgt gccatcttcc agaataagtg
    56461 agacgctcat ggtgtcactg ttggtcgcca gtgactgttt acgcagacgt aataaatcga
    56521 cactggagcg agtgaggtcg acatacattg tatccagacc acgaatagtc gttaacgctg
    56581 tatcctgcga cgcggtcacc agtgcgccag gggttaccga cgaaatacca atacgccccg
    56641 aaatcggtgc ggttaccgtg gtccagtcaa gattaatgcg cgcagtttcc agtgcggctt
    56701 ttttcgcctc tacactggct ttatcttgtg cacaggtaga ctgagcatca tcagcatcct
    56761 gttgtgaaac accattctct ttcaccagtc gggcataacg ctgcgctttc tggcaatcgg
    56821 cttttaccag tgcctgtgct tgttgtaatg ctgcccgggc ttcattccat gcagcctgat
    56881 aactggccgc atcaatctgg tagagaggct gtccagcctt gaccagatca ccttccttaa
    56941 ataagcgttt ctggataatt cccccaacct gcggacgtac ttcagcactg agcgcagcac
    57001 tggtgcgtcc ggttaattca ctgactaccg aaaccggttg agatttgagc gtaacaacgc
    57061 cgacttctgt ttctgacggg gatgaattgt tactttgcgt attatcacaa cccgataaga
    57121 gcagcattgc cactacagat gttgctatat acttcattat tttctccagg gtgagaaata
    57181 ccctcctcat tgaaattaat gaggatatgt cagggatatt cagttataac gaacccgcat
    57241 cgcgaaatga atttcgcaat gaaataaggg ggattaatat cccccgctat tggttaattc
    57301 tgttcttatt tatttatcaa catactaaca atatcctgat atatttcctg cagatgttgt
    57361 ggatcgcttt tttgcggtgt taaacgacga taaaccgtac cttccatcat ggtagcaaac
    57421 acttcaacgc agcaacgaat gtgctcgtcg ctaagatggg gatgcattct tttcatatgt
    57481 gcacaaccgt tagcgaacat tctggcgtca gcttcttcaa gcattgccat aacccgcggg
    57541 ttgcgtgtgg cttctgcagc cacttccagc atcagcgcgt cgtcgtcctc atttaaggat
    57601 ttacgcaagg caaggacttc cgggaagtga tcggtacgcg cgtcaatgtc catttgggca
    57661 atacgaaagt cgatgatacg gcgaaccatc tcttcaataa tggcgtcttt gttggcgaag
    57721 taacgatata tctgacccac gctaagctga gcttcgctgg caatttgcga catactggcg
    57781 gcatgaaatc cgcagcgacg aaaacaccga cgggcggcgt taatgatttc atcctgacgc
    57841 tgtttgtggc gtatctccag cttgctggtc atttctgtct cctggcctat cacttggtga
    57901 gaatgatcat tctcattttt gctaattata cgtttctcca aagtaatgga aagtattttt
    57961 atcttattca tgatgcatat tctgataatg aagagattgt ggagattctg tgaagatagt
    58021 tgacaatatt aagttggagt caattcatca gaaagacagc gacttgttgt cgccagttct
    58081 gttttcatca ttaaacttat aggagctaat acgaatagtt tcaaagtcag attctataag
    58141 atatttcccc aacctccccc ttgcaggcgt caggagtaga taacgcaaaa tgctctgtac
    58201 cgcagcttct ctccgctaca gaaagcgcaa ctatagccac ccacagccag gttgattata
    58261 ataaccgttt atcagttcgt actgtttact aaaacgacga atcgcctgat tttcaggcac
    58321 aacaagcatc aacaataagg attaaagcta tgggttttct ttccggtaag cgcattctgg
    58381 taaccggtgt tgccagcaaa ctgtccatcg cctacggtat cgctcaggcg atgcaccgcg
    58441 aaggagctga actggcattc acctaccaga acgacaaact gaaaggccgc gtagaagaat
    58501 ttgccgctca attgggttct gacatcgttc tgcagtgcga tgttgccgaa gataccagca
    58561 tcgacaccat gttcgctgaa ctggggaaag tttggccgaa atttgacggt ttcgtacact
    58621 ctattggttt tgcacctggc gatcagctgg atggtgacta tgttaacgcc gttactcgtg
    58681 aaggcttcaa aattgcccac gacatcagct cctacagctt cgttgcaatg gcaaaagctt
    58741 gccgctccat gctgaatccg ggttctgccc tgctgaccct ttcctacctt ggcgctgagc
    58801 gcgctatccc gaattacaac gttatgggtc tggcaaaagc gtctctggaa gcgaacgtgc
    58861 gctatatggc gaacgcgatg ggtccggaag gtgtgcgtgt taacgccatc tctgctggtc
    58921 cgatccgtac tctggcggct tccggtatca aagacttccg caaaatgctg gctcattgcg
    58981 aagccgttac cccgattcgc cgtaccgtta ctattgaaga tgtgggtaac tccgcggcat
    59041 tcctgtgctc cgatctctct gccggtatct ccggtgaagt ggtccacgtt gacggcggtt
    59101 tcagcatcgc tgcaatgaac gaactcgaac tgaaataatc gttctgttgg taaatattgg
    59161 gcggcgttct gccgcccgtt atctctgtta tacctttctg atatttgtta tcgccgatcc
    59221 gtctttctcc ccttcccgcc ttgcgtcagg ataacgattt cctttacgac caaggagcgc
    59281 ccatggaaca acgccacatc accggcaaaa gccactggta tcatgaaacg caatccagta
    59341 ctgcggagta tgacgttctg cctctggtcc cggaagccgc aaaggtcagc gatccctttc
    59401 tgctcgacgt gatccttgat gaagaaacgc tggccccctt cctttcatgg ctggtccctg
    59461 cgcgcgttct tgcagtggag ttgttccctg acccgcttac cgtgactcgt tcacagacct
    59521 tcaccgctta tgaacgcttg tcgacggccc tgacggttgc tcaggtttgc ggcgtccaac
    59581 ggttatgtaa ctactattct gcgcgactta cgccgctccc cgggcctgat tcctccaggg
    59641 aaagtaatca tcggttggca caaatcacgc aatatgcccg ccaactggct agctcgcctt
    59701 ctattatcga caaccgatcg cgccagcatc tgaatgacgt tggtcttact gtctgtgact
    59761 gtgtgatcat taaccaaatc attggtttta ttggctttca ggcgcggacc attgcgacat
    59821 ttcaggctta tctcgggcat ccagtacgct ggttacccgg gctggagata caaaactacg
    59881 ccgacgcgtc actgtttgct gatgaatcat tacgctggcg aagcagctat gaggtggaaa
    59941 aactccctga agagcacaca aaaagttcaa ctgcagaact ttgccaactg gccaacacac
    60001 tctctctcca ccctatttca ctttcccttc tcgaaaagtt gttaaacagc acacgggtca
    60061 atacacagcc ggataatcag cttgcggcgt tgttatgcgc gcggataaat ggcagtcctg
    60121 cttgttttgc cgcctgtatg aattcatcaa atgaatataa aaaaatcagc ccccttctgc
    60181 gcaagggcga aaatgaaatt aaccgatggg ctgaccgtca ttctgttgag cgcgctaccg
    60241 ttcaggcgat acaatggctg acccgagcac ccgatcgctt tagcgccgcc cagttcagcc
    60301 cattactcga acacgaaaaa tcatcaacgc agattattaa tctgctagta tggagcgggc
    60361 tgtgtggctg gataaatcgc ttaaaaatcg cgttgggtga gacatattaa ccttgccgcg
    60421 tcagacagat tcgcgtaaaa ctgtcagccg ctctaatggc caccaaaata gacaattatg
    60481 tttcaggaca acccgctgct agcgcagctt aaacagcaac tgcattccca gacgccacgc
    60541 gctgaagggg tggtaaaagc cacagaaaaa ggctttggct tcctggaagt cgacgcgcaa
    60601 aaaagttatt tcattccgcc gccgcagatg aaaaaagtca tgcatggcga ccgaattatc
    60661 gcggtgatcc acagtgaaaa agaacgtgaa tccgcagagc cagaagaact ggttgaaccg
    60721 ttcctgactc gtttcgtggg taaagttcag ggcaaaaatg accgtctggc catcgttcct
    60781 gaccatccac tcttaaaaga cgccattcct tgccgcgcag cccgtggcct gaaccacgag
    60841 tttaaagaag gtgactgggc ggttgccgaa atgcgccgtc atccgctgaa aggcgatcgt
    60901 tctttctatg ctgaactgac acaatacatc acttttggtg acgatcactt tgtaccgtgg
    60961 tgggttaccc ttgcgcgtca taatctggaa aaagaagcac cagacggcgt tgctaccgaa
    61021 atgctcgatg aaggtctggt tcgtgaagat ctgactgcgc tggattttgt caccatcgac
    61081 agtgccagca cagaagatat ggatgacgcc cttttcgcca aggcgttacc ggatggcaaa
    61141 cttcagctga ttgtggcgat tgccgatcca accgcgtgga ttgctgaagg cagcaagctg
    61201 gacaaagccg cgaaaattcg cgcattcacc aactatctgc ctggcttcaa catccctatg
    61261 ctgcctcgcg agctttctga cgatctctgc tcactgcgcg ccaatgaagt ccgcccggta
    61321 ctggcatgcc gcatgacgct ctccactgat ggcaccattg aagataatat cgaattcttt
    61381 gccgccacca tcgaatccaa agcgaagctg gtgtatgacc aggtttctga ctggctggaa
    61441 aataccggtg actggcagcc tgaaagcgaa gcaattgccg aacaagtccg tttgctagca
    61501 caaatttgcc aacgccgcgg cgagtggcgt cataaccacg cactggtgtt taaagatcgc
    61561 ccggattacc gctttattct cggtgaaaaa ggtgaagtgc tggatatcgt cgccgagcct
    61621 cgtcgcattg ccaaccgtat cgtcgaagaa gcgatgattg ccgctaacat ttgtgcggcc
    61681 cgcgtactgc gcgataagct cggttttggc atctataacg tgcatatggg ctttgatccg
    61741 gcgaatgccg acgcgctggc agcgttgctg aaaacgcacg gtctgcatgt cgatgctgaa
    61801 gaagtgctca cgctggacgg tttctgcaaa ctgcgtcgtg aactggatgc gcaaccaact
    61861 ggtttcctcg acagccgcat tcgtcgcttc cagtcatttg ctgaaattag cactgaaccc
    61921 ggtcctcact ttggcctcgg tctggaagca tacgccactt ggacttcgcc gatccgtaaa
    61981 tatggcgaca tgatcaacca ccgtctgctg aaagcggtta tcaaaggcga aactgcgacg
    62041 cgtccacagg atgaaatcac tgtccaaatg gccgagcgtc gccgtctcaa ccggatggca
    62101 gaacgtgatg ttggcgactg gttatacgca cgcttcctga aagacaaagc cgggaccgac
    62161 acccgtttcg cggcggaaat tgtcgatatc agccgtggcg gcatgcgtgt tcgtttggtt
    62221 gataacggcg ctatcgcctt tattccagca cctttcttac acgctgtgcg cgatgaactg
    62281 gtttgcagcc aggaaaacgg cactgtacaa attaaaggtg aaacggctta caaagtgact
    62341 gacgttattg acgtcaccat tgccgaagtc cgcatggaaa cccgcagcat tattgcgcgc
    62401 ccagtcgcgt aatctccttt cacggcccat tcctcatgga tgggccgttt atttccccgc
    62461 tcaaccttcg tcatatcccg gcagattttt aactgac
//
LOCUS       DAPOXO010000017        62116 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPOXO010000017 DAPOXO010000000
VERSION     DAPOXO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 62116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62116
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.017"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..726)
                     /gene="tolA"
                     /locus_tag="ROH59_001381"
     CDS             complement(<1..726)
                     /gene="tolA"
                     /locus_tag="ROH59_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HDX4803889.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAVEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAEKA"
     gene            complement(791..1219)
                     /gene="tolR"
                     /locus_tag="ROH59_001382"
     CDS             complement(791..1219)
                     /gene="tolR"
                     /locus_tag="ROH59_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HDX4803890.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            complement(1223..1915)
                     /gene="tolQ"
                     /locus_tag="ROH59_001383"
     CDS             complement(1223..1915)
                     /gene="tolQ"
                     /locus_tag="ROH59_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HDX4803891.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLSGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            complement(1912..2316)
                     /gene="ybgC"
                     /locus_tag="ROH59_001384"
     CDS             complement(1912..2316)
                     /gene="ybgC"
                     /locus_tag="ROH59_001384"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDX4803892.1"
                     /translation="MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENT
                     LLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ"
     gene            complement(2466..2759)
                     /gene="ybgE"
                     /locus_tag="ROH59_001385"
     CDS             complement(2466..2759)
                     /gene="ybgE"
                     /locus_tag="ROH59_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HDX4803893.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGFFCPLLADIVLIVGLIFFFF"
     gene            complement(2759..2872)
                     /gene="cydX"
                     /locus_tag="ROH59_001386"
     CDS             complement(2759..2872)
                     /gene="cydX"
                     /locus_tag="ROH59_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HDX4803894.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            complement(2887..4026)
                     /gene="cydB"
                     /locus_tag="ROH59_001387"
     CDS             complement(2887..4026)
                     /gene="cydB"
                     /locus_tag="ROH59_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDX4803895.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            complement(4042..5610)
                     /gene="cydA"
                     /locus_tag="ROH59_001388"
     CDS             complement(4042..5610)
                     /gene="cydA"
                     /locus_tag="ROH59_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415261.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HDX4803896.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
     gene            complement(7153..8346)
                     /locus_tag="ROH59_001389"
     CDS             complement(7153..8346)
                     /locus_tag="ROH59_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDX4803897.1"
                     /translation="MKKIVLPVALALLGMNAGAYAADVSIDILSATVKDKRIEGASVT
                     LQRNGAQSVSGITNTSGSISLGTSFADNKDALLIVKKEGYSNLVVKCPCAGMTYAISP
                     VMTNLDGMRVVLSWGEKPFDLDSHLIFPGGHIYFDSKEGTDANLDVDDTDSYGPETVT
                     ISKKHFGESYIYAVQDYSNKGLPNSNYLSASKAKVFVYVGSSLVRSYSVPAGKRGNIW
                     TVFKLNPNGEFEDINSVTSANFNGTTLDVRDLATVIMPATDSSAPASPAMQNSGDTQL
                     ARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGNIAEAIWAN
                     RKAISLASGVNAATTRANSYYNIAKIYETSGQNAEALQHYQLAYTEKNKPSYEEAIAR
                     VKTKM"
     gene            complement(8544..11177)
                     /gene="mngB"
                     /locus_tag="ROH59_001390"
     CDS             complement(8544..11177)
                     /gene="mngB"
                     /locus_tag="ROH59_001390"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDX4803898.1"
                     /translation="MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQD
                     NEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEGGKLIIGPWYTQTDTTIVSAESIV
                     RNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
                     TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLP
                     NGHDQMPLQQNIFEVMEKLREIYPQRKFVMSRFEEVFEQIEAQRESLAILKGEFIDGK
                     YMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFDYHHGLLEKMWKEILK
                     NHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNL
                     MPWPREEVINTTVRLRGSQFNLRDGRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPF
                     MEFDIQISQIVPSMGYRTLYIEANQLGNVVTPKSKTEGILENAFWQIALNEDGSLRLV
                     DKDSGVRYDRVFQIEEGSDDGDEYDYSPAKEEWAITSANAKPQYDIIHEAWQSRAIIR
                     YEIAVPRNLSERRAKQCSGRVGVETVITLSHNSRRIDADINLDNQADDHRIRVLIPTP
                     FNTDVVLADTQFGSLTRPVKDCAMNVWQQEGWKEAPVPVWNMLNYAVLQEGRNGIAVF
                     SEGLREFEVIGEENKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVSDSQLRGSFSC
                     RLSLFSYIGTPVTAGVAQQARAWLTPVQCYNKIPWDAMKLNKAKFNVPESYSLLKMPP
                     VGCLISALKKAEDRQELILRLFNPAELTSCDATVAFSRKVMTCTETMMNERFNTEKNE
                     VLKELALFLPGQSRTFSYRIV"
     gene            complement(11195..13111)
                     /gene="mngA"
                     /locus_tag="ROH59_001391"
     CDS             complement(11195..13111)
                     /gene="mngA"
                     /locus_tag="ROH59_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDX4803899.1"
                     /translation="MNLTTLTHRDALCLNVRFTSREEAIHALTQRLAALGKISSTEQF
                     LEEVYCRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVV
                     LLAIPPNEAGTTHMKLLTALTTRLADDELRARIQSATTPDELLSALDDKGDAQHTASF
                     SYAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNIYVEKQGANGIEERLTAEQLNS
                     ATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDT
                     QPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMY
                     RKLGGGMLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAG
                     YLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNG
                     LSGNNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFT
                     VTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTG
                     AIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRHH
                     AVKHGNYLTDGVMP"
     gene            13280..14002
                     /gene="mngR"
                     /locus_tag="ROH59_001392"
     CDS             13280..14002
                     /gene="mngR"
                     /locus_tag="ROH59_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-D-glycerate transport/metabolism system
                     transcriptional repressor MngR"
                     /protein_id="HDX4803900.1"
                     /translation="MGHKPLYRQIADRIREQITCGELKPGDALPTESALQTEFGVSRV
                     TVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVETHSEVLIF
                     EVIPADNFLQQQLQISEQDRVWHVKRVRYRKQKPVALEETWMPLALFPDLTWQVMENS
                     KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGQVFEY
                     SRNAFNTDDYKFTLIAQRKSPR"
     gene            complement(14106..14975)
                     /gene="sucD"
                     /locus_tag="ROH59_001393"
     CDS             complement(14106..14975)
                     /gene="sucD"
                     /locus_tag="ROH59_001393"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HDX4803901.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(14975..16141)
                     /gene="sucC"
                     /locus_tag="ROH59_001394"
     CDS             complement(14975..16141)
                     /gene="sucC"
                     /locus_tag="ROH59_001394"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HDX4803902.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            complement(16235..17452)
                     /gene="odhB"
                     /locus_tag="ROH59_001395"
     CDS             complement(16235..17452)
                     /gene="odhB"
                     /locus_tag="ROH59_001395"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HDX4803903.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDVVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            complement(17467..20268)
                     /gene="sucA"
                     /locus_tag="ROH59_001396"
     CDS             complement(17467..20268)
                     /gene="sucA"
                     /locus_tag="ROH59_001396"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HDX4803904.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAISEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            complement(20630..21346)
                     /gene="sdhB"
                     /locus_tag="ROH59_001397"
     CDS             complement(20630..21346)
                     /gene="sdhB"
                     /locus_tag="ROH59_001397"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HDX4803905.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            complement(21362..23128)
                     /gene="sdhA"
                     /locus_tag="ROH59_001398"
     CDS             complement(21362..23128)
                     /gene="sdhA"
                     /locus_tag="ROH59_001398"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HDX4803906.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            complement(23128..23475)
                     /gene="sdhD"
                     /locus_tag="ROH59_001399"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             complement(23128..23475)
                     /gene="sdhD"
                     /locus_tag="ROH59_001399"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HDX4803907.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            complement(23469..23873)
                     /gene="sdhC"
                     /locus_tag="ROH59_001400"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             complement(23469..23873)
                     /gene="sdhC"
                     /locus_tag="ROH59_001400"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDX4803908.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPVTAIASILHRVSGVITFV
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            24254..24361
                     /locus_tag="ROH59_001401"
     CDS             24254..24361
                     /locus_tag="ROH59_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803909.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            24567..25850
                     /gene="gltA"
                     /locus_tag="ROH59_001402"
     CDS             24567..25850
                     /gene="gltA"
                     /locus_tag="ROH59_001402"
                     /EC_number="2.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HDX4803910.1"
                     /translation="MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYAQRDFKSDIKK"
     gene            complement(25897..27207)
                     /locus_tag="ROH59_001403"
     CDS             complement(25897..27207)
                     /locus_tag="ROH59_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000126139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HDX4803911.1"
                     /translation="MTALSELLAGSWLDNWLMIIPLMFVCLFINMPVWLAMFCGILTY
                     FLCYSNVPLMVAIQRLIATTQTPSLLAIPFFILLGTLMSYTGIAARILQIANVLIGRM
                     RGGLGGANILVSTMMGGVSASNLADAAMLSRMMVPEMEQKGYSRGFAAAITASGSLIT
                     PIIPPGIALILYGLVADVSIGSMFMAGILPGLLCSAMLIVTVWLVAIRRGLKPSSEHW
                     PKPKEVSVALVQAWPALFLIVAVIGGIRANIFTPTEAGAVAVLLVMFIGFVIYRELKI
                     SHVFTALSETARSTASVMLIIMASAALGWIFSLERAGITVAEFVTSLTDNKYVFLLII
                     NLLLLVLGMFLEGSAILLILVPLLKPVVAHFGIDPVHFGIIMILNLSLGTLSPPVGTV
                     MLLVCNTVQVSVGQFMREAVPLLISLILLLLVITYIPAISLLLV"
     gene            complement(27207..27668)
                     /locus_tag="ROH59_001404"
     CDS             complement(27207..27668)
                     /locus_tag="ROH59_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDX4803912.1"
                     /translation="MRLLGKMIEVAAVLTLFILVIMTIAAVIMRYCFHMPLQWTEEVS
                     GLLMIWVVMFGAVVAERDNTHLSIPFLADALTSRGQRILAFLVSLMSIILLVVMAWSA
                     WKLAAGTAFKTTQILKISWFWIDIAVTVGAIGVACFTALQLIKKTPRKEGE"
     gene            complement(27728..28696)
                     /locus_tag="ROH59_001405"
     CDS             complement(27728..28696)
                     /locus_tag="ROH59_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate TRAP transporter
                     substrate-binding protein"
                     /protein_id="HDX4803913.1"
                     /translation="MKKLLTPLLFLLALFSPMLNAAPVTIKIAYESNPGEPADTVVKH
                     WAELVKKKSNGDIVFELYPSSQLGSKQDITEQALMGMNIITISDVGFLTDYDADLGIL
                     FGPYLTEDPQKLFAIYASDWFKQKEQKLREKGVHIVMSNYLYGTRQIIAKKPIRTPED
                     LKGMKIRVPNNVMQIKAIEAMGATPTPMPLGDVYPALTQGMIDGVENPVSVLYGQKLH
                     EQAKYLSMVNYLTNTSLWLGGEAFFSTLTPAQLDIIHQTAYEAGLYSQKITTEQDATM
                     LKTMQEQGVEIIYPDVAPFKEKALKVYQQFPEWTPGLYDTIQQQLK"
     gene            complement(28724..29920)
                     /locus_tag="ROH59_001406"
     CDS             complement(28724..29920)
                     /locus_tag="ROH59_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDX4803914.1"
                     /translation="MEGYVRQNGRPGIRNTVQVIFMVECASHVAKKIAEGFPCHDVQY
                     FGFSGCYPSDYGYRLVKNLATHSNVGGVLIISLGCENFDRRRLEQEVRESGRPCHTLV
                     IQENKGTTNTITLGKQLVAEMLEQLADTPRCILNWSDLVVGTICGGSDGTSGITGNPA
                     VGRAFDQLLEKGATCIFEESGELLGCEQHMMSRAASSQARDAIEVAMTKAERYYSLMG
                     LGSFSNGNAEGGLTTQEEKSLGAYTKSGDALIAGVILPTQQTPFPGLWLMDVVPDGEP
                     RFGYPNINDSSEALELIASGCHMVLFTTGRGSVIGSVIAPIIKVCNNPQTWEHLSDDM
                     DVNAGRVISEGATLDDIADDIMQVIEHVANGQYCAAERLEHQEFVLTYKAFDYSKSAV
                     CRADPR"
     gene            complement(29920..30231)
                     /locus_tag="ROH59_001407"
     CDS             complement(29920..30231)
                     /locus_tag="ROH59_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002432396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDX4803915.1"
                     /translation="MRKRALKLHAKDNCVVALNDIASGDIVWWDEGEMVACSSVTLGH
                     KLACEALNNGDSILKYGAIIGHATRDIAMGEHVHSHNLASNAIAIFHHDDAGYQSEEK
                     A"
     gene            complement(30246..31001)
                     /locus_tag="ROH59_001408"
     CDS             complement(30246..31001)
                     /locus_tag="ROH59_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4803916.1"
                     /translation="MNAFSLHNKTALITGAASGLGLAMAKCMIVSGAKVIIADLNGEL
                     AQATAGTLGSQASWIQMDVGDTAAAQEKVDVLISEHGAIDILVNNAGNHCKKPIEEMS
                     VSDFESVLDVHVVGAFALTKALVPHMKQRGKGCVLFTASMTSFLGQPLVTGYSAAKSA
                     YLGMIRGMTTELAVHGIRVNGIAPGWIDTPMLRKAIEGDDERRNKILGRTPMKKFGKP
                     EDIGWAAVYLASDAAAFVSGQVLVVDGGALIGF"
     gene            complement(31013..32026)
                     /locus_tag="ROH59_001409"
     CDS             complement(31013..32026)
                     /locus_tag="ROH59_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDX4803917.1"
                     /translation="MKALTIEQGSQARFVDIPEPVCGKGEVLINVERVGLCGSDLNTW
                     RGLNPLVNYPCIPGHEIGGTVLATGDMAGAIKPGDRVVVLPCTECGVCSSCLSGRPNA
                     CKNNQTLGVQRQGGMAQQLTMPAHKVIVCNALSVDELALVEPLAVGLHAARRAQINVG
                     EWVAVIGCGVIGLGAIAAASAMGARVIAIDIDDRKRNIALECGAQRFLNSQQCDVAAE
                     LVLLNDGRGPEVVIEAVGNQQTIEQATGLVAFSGRVVYVGYAKQPVSYQSAQFLMKEL
                     DIRGSRNATVADFRAVLALMESGRYPVSNLVSAHYPLEQADHAFSDWASDPGAYTKIL
                     IDL"
     gene            complement(32039..32725)
                     /locus_tag="ROH59_001410"
     CDS             complement(32039..32725)
                     /locus_tag="ROH59_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RraA family protein"
                     /protein_id="HDX4803918.1"
                     /translation="MWKSDNELFALMKTRLFTAVVGDILDTLGYMHQFVSPAIKPLDV
                     NTVVAGRAMPVLESDVYETKSTSGKTAIGEKPFGIMFEALDALKENDVYITTGSSLRY
                     ALWGGLMSTRAMHLKAAGAVLDGYARDSAEILELKFPTFCHGTYAQDQGPRGKVIDFG
                     VPIEFHGVRVNPGDIVFGDRDGLLIIPQVVEKEVITQALEKVATESEVRKAISDGMST
                     VQAFETFGVM"
     gene            32989..33702
                     /locus_tag="ROH59_001411"
     CDS             32989..33702
                     /locus_tag="ROH59_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDX4803919.1"
                     /translation="MSESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEVQLIQK
                     LGVSRGIVREAYRSLAALGILETHSGKVPRIKKFDDEVLRVVFGFALATEQVTTEQIL
                     QVRRWLELGVVEAAARNGEEEDFANLRAEMAKIREQFNDVESFITHDIRFHQLLAVAS
                     KNPLFMMLLQALHQQLRQSIQEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATQ
                     AMKSHFDSPVSALINNSSS"
     gene            33882..34928
                     /locus_tag="ROH59_001412"
     CDS             33882..34928
                     /locus_tag="ROH59_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDX4803920.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLALHLPAALLLGPMIAGIIFSMHG
                     VTLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQQIVWFPPVSINLLLTILLAVVAGTAGCLLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIIAMQTLRLFSILLTGPA
                     IARFISTYAPKRSA"
     gene            complement(34925..35716)
                     /gene="nei"
                     /locus_tag="ROH59_001413"
     CDS             complement(34925..35716)
                     /gene="nei"
                     /locus_tag="ROH59_001413"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HDX4803921.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKSYQSRLIGQH
                     VTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAPQLDALAHALLDIPRLSYATRGQVDE
                     NKYHGALFRFKVFHRDGEPCERCGGIIEKTTLSSRPFYWCPGCQH"
     gene            complement(35752..36486)
                     /gene="pxpA"
                     /locus_tag="ROH59_001414"
     CDS             complement(35752..36486)
                     /gene="pxpA"
                     /locus_tag="ROH59_001414"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HDX4803922.1"
                     /translation="MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETIFAQTLYQIGALAAITRAQGGVMCH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGERYGLVTREEVF
                     ADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWAMVTAQTVCLH
                     GDGEHALAFARRLRATFAEKGIVVAA"
     gene            complement(36476..37408)
                     /gene="pxpC"
                     /locus_tag="ROH59_001415"
     CDS             complement(36476..37408)
                     /gene="pxpC"
                     /locus_tag="ROH59_001415"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HDX4803923.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLRDGDRLPIGKAKRDFM
                     EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSPQSNRMGYRLQGQILKR
                     TTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            complement(37402..38058)
                     /gene="pxpB"
                     /locus_tag="ROH59_001416"
     CDS             complement(37402..38058)
                     /gene="pxpB"
                     /locus_tag="ROH59_001416"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDX4803924.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EAIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAAGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLHVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPACDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            complement(38081..38824)
                     /gene="ybgI"
                     /locus_tag="ROH59_001417"
     CDS             complement(38081..38824)
                     /gene="ybgI"
                     /locus_tag="ROH59_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HDX4803925.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKEMVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            39095..40576
                     /gene="dtpD"
                     /locus_tag="ROH59_001418"
     CDS             39095..40576
                     /gene="dtpD"
                     /locus_tag="ROH59_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HDX4803926.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYSD
                     NHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGF
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITVLFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES"
     gene            complement(40618..42036)
                     /gene="phrB"
                     /locus_tag="ROH59_001419"
     CDS             complement(40618..42036)
                     /gene="phrB"
                     /locus_tag="ROH59_001419"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HDX4803927.1"
                     /translation="MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWAA
                     HNVSPRQAELINTQLNALQNALAEKGIPLLFREVDDFAASVEIVKQVCAENRVTHLFY
                     NYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGAIDPAPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQN
                     GAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLSEL
                     IWREFYRHLMTYYPSLCKHRPFIAWTDRVQWQSNPAHLKAWQEGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPTTQGEKFDREGEFIRQWLPELRDVPGKAVHEPWKWAEKTGVTLDYPQP
                     IVDHKEARLRTLAAYEEARKGA"
     gene            complement(42033..42542)
                     /locus_tag="ROH59_001420"
     CDS             complement(42033..42542)
                     /locus_tag="ROH59_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HDX4803928.1"
                     /translation="MNQQLFDDSTLIRIFALHELHNLKDRGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHRWQSLDDYYNQYRQRVIVLLSHPANRRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRRGEQSLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHAGVL"
     gene            complement(42643..42849)
                     /locus_tag="ROH59_001421"
     CDS             complement(42643..42849)
                     /locus_tag="ROH59_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HDX4803929.1"
                     /translation="MELYKEYPAWLIFLRRTCAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMDQAEKATGDFY"
     gene            43162..43251
                     /gene="kdpF"
                     /locus_tag="ROH59_001422"
     CDS             43162..43251
                     /gene="kdpF"
                     /locus_tag="ROH59_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDX4803930.1"
                     /translation="MSAGVITGVLLVFLLLGYLVYALINAEAF"
     gene            43251..44924
                     /gene="kdpA"
                     /locus_tag="ROH59_001423"
     CDS             43251..44924
                     /gene="kdpA"
                     /locus_tag="ROH59_001423"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDX4803931.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVER
                     VLFSALGVSDREMNWKQYLSAILGLNILGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGD
                     RRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLALCMFVGRFGVIIPVMAIAGSLV
                     SKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            44947..46995
                     /gene="kdpB"
                     /locus_tag="ROH59_001424"
     CDS             44947..46995
                     /gene="kdpB"
                     /locus_tag="ROH59_001424"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDX4803932.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTCISIAMASGVMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAVADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            47004..47576
                     /gene="kdpC"
                     /locus_tag="ROH59_001425"
     CDS             47004..47576
                     /gene="kdpC"
                     /locus_tag="ROH59_001425"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDX4803933.1"
                     /translation="MSGLRPALSTFLFLLLITGGVYPLLTTALGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPVLDKQIAARV
                     AALRAANPDASTSVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVNYIGQPVVNVVELNLALDKLDE"
     gene            47569..50253
                     /gene="kdpD"
                     /locus_tag="ROH59_001426"
     CDS             47569..50253
                     /gene="kdpD"
                     /locus_tag="ROH59_001426"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HDX4803934.1"
                     /translation="MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPLKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDSRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSSQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGINAHIEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM"
     gene            50250..50927
                     /gene="kdpE"
                     /locus_tag="ROH59_001427"
     CDS             50250..50927
                     /gene="kdpE"
                     /locus_tag="ROH59_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HDX4803935.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETG
                     IGYRFMP"
     gene            51202..51306
                     /locus_tag="ROH59_001428"
     CDS             51202..51306
                     /locus_tag="ROH59_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2618 domain-containing protein"
                     /protein_id="HDX4803936.1"
                     /translation="MENNNRLMPHIRRTTHIMKFAHRNSFDFHFFNAR"
     gene            51616..53814
                     /gene="speF"
                     /locus_tag="ROH59_001429"
     CDS             51616..53814
                     /gene="speF"
                     /locus_tag="ROH59_001429"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase SpeF"
                     /protein_id="HDX4803937.1"
                     /translation="MSELKIAVSRSCPDCFSTHRECVNIDKSNYIDVAAIILSVNDVE
                     HGKLDEIDATGYGIPVFIATENEERVPAEYLPRISGVFEHCESRKEFYGRQLETAASH
                     YETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
                     NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVL
                     FDRNNHKSNHHGALLQAGATPVYLETARNPYGFIGGIDAHCFEESYLRELITEVAPQR
                     AKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCS
                     PLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMH
                     ASTSPFYPLFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELV
                     DGKPWQSYETAQIAVDLRFFKFVPGEHWHSFEGYAENQYFVDPCKLLLTTPGIDARNG
                     EYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVRFEKLL
                     EADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRV
                     SMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFS
                     ALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRDAQSALLKGEKL"
     gene            53811..55130
                     /gene="potE"
                     /locus_tag="ROH59_001430"
     CDS             53811..55130
                     /gene="potE"
                     /locus_tag="ROH59_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HDX4803938.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQS
                     GLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            complement(55187..56827)
                     /gene="pgm"
                     /locus_tag="ROH59_001431"
     CDS             complement(55187..56827)
                     /gene="pgm"
                     /locus_tag="ROH59_001431"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HDX4803939.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAISNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALLADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(56853..57398)
                     /gene="seqA"
                     /locus_tag="ROH59_001432"
     CDS             complement(56853..57398)
                     /gene="seqA"
                     /locus_tag="ROH59_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HDX4803940.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFTAASQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVCGTI"
     gene            57583..58347
                     /gene="ybfF"
                     /locus_tag="ROH59_001433"
     CDS             57583..58347
                     /gene="ybfF"
                     /locus_tag="ROH59_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDX4803941.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALA
                     PDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPTLFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            58487..58780
                     /gene="ybfE"
                     /locus_tag="ROH59_001434"
     CDS             58487..58780
                     /gene="ybfE"
                     /locus_tag="ROH59_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HDX4803942.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV"
     gene            58920..59450
                     /gene="fldA"
                     /locus_tag="ROH59_001435"
     CDS             58920..59450
                     /gene="fldA"
                     /locus_tag="ROH59_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HDX4803943.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            59660..59746
                     /gene="uof"
                     /locus_tag="ROH59_001436"
     CDS             59660..59746
                     /gene="uof"
                     /locus_tag="ROH59_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HDX4803944.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            59739..60185
                     /gene="fur"
                     /locus_tag="ROH59_001437"
     CDS             59739..60185
                     /gene="fur"
                     /locus_tag="ROH59_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HDX4803945.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(60269..60595)
                     /locus_tag="ROH59_001438"
     CDS             complement(60269..60595)
                     /locus_tag="ROH59_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803946.1"
                     /translation="MKKLILIAMMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFAEQESVRVLDYQQCIQATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(60645..62051)
                     /gene="chiP"
                     /locus_tag="ROH59_001439"
     CDS             complement(60645..62051)
                     /gene="chiP"
                     /locus_tag="ROH59_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HDX4803947.1"
                     /translation="MRAFSGKRSTLALAIAGVTAMSGFMAIPEARAEGFIDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSLGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSANDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
BASE COUNT        15043 a        16455 c        15244 g        15374 t
ORIGIN      
        1 cgctttttct gctgcttttt tgtcggctgc cgctttctct gctgccgctt tcttctcagc
       61 ttctgccttg gctttttcag cagcttcggt tgccgctttc tttcttgctt cagctgcagc
      121 tgcttctgcc gcttcagctt tcttcttcag cgccgcagca gcagcctcgg cttttttctg
      181 cgcttcgact gcggctttgg cggcttctgc ttctgctttt ttcttcgcgt ctgccgccgc
      241 tttcttcgct gcttcttccg cagctttagc atccgcttcg gccttcgctt tagcatctgc
      301 cgccgctttc gctgccgcct cttccgcttg cttctgcttt aactcggcct gttttgcggc
      361 ttcttcagcc tgctttttct gctcctgagc cgctaaccgc tctttctcaa gttgcttcag
      421 gcgttcctgt tcagccgctt gtttctcacg cagttcttca gcagcctgct gctctttcat
      481 cttgcgctgc tcatcagaac gcttcgcgct tgattcctgg ctttgcatgc gtttgtactg
      541 ctcaactacc gcacctgaat caaccatgac agcgtcgatg gacgaaccac cgccgcctcc
      601 ggctgaagct tctatattct catcgaacga actccagatc agcgccgcaa ataagatgac
      661 atgcagcact gctgaaataa ttatcgcccg cttgagcttg tcgttttgtt cggttgcctt
      721 tgacactctc ggtttccaaa aactgttcgc ctgttacccg ctctctttca agcaagggaa
      781 acgcagatgt ttagataggc tgcgtcatta aaccaaccga tttcacaccc gcactatgta
      841 acaagttcag tgctttaatt atttcatcgt aaggcacatc ttttgcgcca ccgatcagaa
      901 agaccgtttt cgggttggcc ttgaaacggc tggacacttc cgccaccacc tgctctggtg
      961 gtaaacgctc caggcgatct ttctcaacca ccacggtgta ctgaccaata ccagacactt
     1021 caacaatcac tggcggatta tcgttactgc tcaccgcctg tgattcagta gcgtctggca
     1081 gatcgacctc cacgctctgg gtgatgatgg gcgctgtcgc cataaagatc agcaacagca
     1141 ccagcagtac gtccagcaac ggtacaatgt tgatttcgga cttgagatcg cgacgacctc
     1201 gtccacgcgc tctggccatg gcttacccct tgttgctctc gctaacggta aacgcctggc
     1261 ggtgcagaat cgcggtaaac tcttccataa agttgtcgta attcagttcc agtttgttta
     1321 cgcgctggtt gagacggtta taagccatta ccgccggaat tgcggcgaac aaaccaattg
     1381 ccgtcgcaat caacgcttct gcgataccgg gcgcaaccat ttgcagtgtt gcttgtttta
     1441 ccgccccgag ggcgataaag gcgtgcatga tcccccagac cgtaccaaac agaccaatat
     1501 acgggctgat ggagccaacc gtaccgagga acggaatgtg cgtttccaga ttttcaagtt
     1561 cacgattcat ggaaatacgc atcgcacgcg acgccccttc cactacggct tccggcgcat
     1621 ggctattggc acgatgcagg cgcacaaact ctttgaagcc gctgtaaaag atttgttccg
     1681 aaccgctcag attatcccgt ttcccctggc tctcttgata gaggcgagag agttcgattc
     1741 cagaccagaa tttatcttca aacgcttcgg cttcgcgcgc cgctgcgtta agaatacggg
     1801 tccgctggat aataatggcc caggatgcga ttgaaaaacc aatcaaaatc aacatgataa
     1861 gtttaaccag aaggctagcc ttcaggaaca aatcaaggat attcatgtca gtcactgctt
     1921 aaactccgcg acaatagact tgggaagcgc acgaggcttc attttgagtg ggtcaacgca
     1981 aacaaccaga acctctgctt cattcaacaa agtattctcg gcgttgacaa tacgttgcgt
     2041 gaaaaccaaa gaggtgccac gcattgatgt tatttcagtc tgtatttcga gcatatcgtc
     2101 gagccgcgca ggtgcgtaat attccaccgt cattttacgt accacaaagg caacgcgttc
     2161 agccatcagc gcctgttgac tgaaatgatg atgacgcagc atctctgtgc gtgctctttc
     2221 ataaaaagcg acgtaactgg cgtggtacac cacaccaccg gcatcggtat cttcatagta
     2281 gacgcgaacc ggccatcgaa acagcgttgt attcacttta catcccggta atgcaacaaa
     2341 agttagagct tttaaacgct gctactatac gcgcgcgatt gaggtttggg aatgagggca
     2401 agttaaggga gcgtaaaaat ttatgggcct gactcggccc ataaattttt aaagagaatt
     2461 ctgatttaaa agaagaagaa aatcagcccg acaatgagaa caatatcggc aagcaatggg
     2521 caaaaaaacc cttgccagag aaccttctgc ggacgaaagc ccacgccgtg aatcacacca
     2581 gcacagacgg cccacataag cagtaaacca tgccagattt ccagttcact ggtcttcgcg
     2641 gcgaaacgtg atgggtccca aaacatacat cctgctaaca gaagtgccat cacgaaggaa
     2701 agcgcccgca gggggcgctt gtccattacc gcatacaagg ttgcgataat cttactcatc
     2761 agatgtcttc ttgaccggct ttgcctgatt cgacgtgctc aagcgccagc gcggtgatta
     2821 ccccaaacga acaggcaaga agcgttccca gaatccatgc gaaataccac atttttagct
     2881 ccttacttag tacagagagt gggtgttacg ttcaatatct tctttggtga tacgaccgaa
     2941 cattttccag taacaccagg cggtgtagag cagaatgatc ggtaccagaa ccaccgcaac
     3001 ccaggtcatg acgttaagcg tcagctggct ggaagttgca tcccacattg tcagacttgc
     3061 gttcatcatg gtgctggacg gcatcacaaa cgggaacatt gcgataccgg cagtcaggat
     3121 gatgcaggcc agcgtcaggg aggagaaaac aaacgcccac gcggctttat ccatacgtgc
     3181 agtcaggatg gtcagcagcg gcagaaccac acccagtgcc ggaatagccc acagaattgg
     3241 cgtgttgttg aagttaacca gccatgcgcc agcttcacga accacttctt tattcagcgg
     3301 gttagaggct gcgtaatggt ccattgtcga tttcacgaca taaccatcga taccgtacat
     3361 cacccatacg ccagccagtg cgaagcagac cagcgtcacc agtgccgcca cctgagccgt
     3421 tgcacgggta cgcaggtgca gttcgcccac ggtacgcatt tgcagatagg ttgcgccctg
     3481 agtaatgatc atccctacgc tcaccacacc tgccagcagg ccgaacgggt taagcagctg
     3541 gaagaagtta ccggtgtagt acagacgcag atattcatca acgttgaatg gtacgccctg
     3601 caacaggtta ccgaacgcta caccaatcac cagcggcgga acgaagctac caatgaagat
     3661 gccccagtcc cacatgttac gccagcgggt ttcttcaatc ttggagcggt agtcaaaacc
     3721 gaccggacgg aagaacaaag acgccagtac gaggatcatc gccacataga agccggagaa
     3781 cgcagcggca tagaccatcg gccaggcagc aaacagtgca ccgcctgcgg tgatcagcca
     3841 aacctggtta ccgtcccagt gtggtgcgat ggagttaatc ataattcgac gctcggtgtc
     3901 gttacgaccg aggaaacggg tgagcatgcc cacccccatg tcgaaaccgt cagtgactgc
     3961 aaaaccaatc agcagaacgc caaccagcag ccaccagata aaacgcaata cttcataatc
     4021 gatcatttga cgactcctgt cttagcgtgc cggctgagta gtcgtggaag actgctcaaa
     4081 gtgatagcga ccggttttca ggctgcttgg gccgaggcgt gcaaacttga acattaagaa
     4141 caattctgcc accaggaaca gggtatacag gccgcaaatc agcaccattg agaagatgag
     4201 atcgcctgcg gtcagtgacg agttcgccac agctgtcggc agcacttcac cgatagccca
     4261 cggttggcgg ccatattcag ccacgaacca gcccgcttct acagcaatcc acggcagcgg
     4321 aataccgtac agcgcggcgc gcagcagcca ttttttctcg ccaatgcggt tgcggatgac
     4381 actccagaaa gagagcgcaa tgattgccag cagcaggaag ccacacgcca ccatgatacg
     4441 gaacgcgaag tacagcggcg ctacacgcgg aatggagtct ttggttgcct gttgaatctg
     4501 agcttcagtc gcatcagcca cgtttggcgt atagcgtttc agcagcagac cgtaaccgag
     4561 atctttcttc atgctattga actggtcacg aacggcctgg tcagtagaac cagaacgcag
     4621 ttgttcgagc agagagtacg ccttcatccc gttacgaatg cgttcttcat gctgcaccat
     4681 cagttctttc agaccgataa ctggagtatc cacggaacgc gttgcaatga tgcccagcgc
     4741 gtaagggatc tggatcgcaa atttgttcgt ctcctcttcc tgatcaggaa tgccgaacag
     4801 agtaaaggca gcaggtgcag gttgcgtttc ccactcggct tcaatagcag ccagtttggt
     4861 tttctgcacg tcgcccattt cgtagccgga ttcatcaccc agaacaataa cagacagaac
     4921 ggcagccata ccgaagctgg cagcgatagc aaaggagcgt ttagcgaagg cgaagtcacg
     4981 acctttcagc atataccatg cgctgatacc gaggatgaac atcgcgccag tcacataacc
     5041 agaagctacg gtgtgaacga atttcacctg agcaaccggg ttaagcacca gctcggagaa
     5101 gctcaccatc tccatacgca tagtttcaaa gttgaaatcg gacgcgattg ggttttgcat
     5161 ccagccgttt gcaaccagaa tccacagtgc ggacaggttt gaaccgagcg ccaccagcca
     5221 ggtgacacac atatgctgaa ctttacccag acgatcccaa ccgaagaaga acagacctac
     5281 aaaggtggat tcgaggaaga aggccatcag accttcgatt gccagcggcg caccgaagat
     5341 atcccctaca tagtgggaat agtaagacca gttagtcccg aactggaact ccatggtcag
     5401 accggtagcc acacccagag caaagttgat accaaacaac ttgccccaga acttggtcat
     5461 atctttataa atctgtttgc cggaaaggac gtagaccgtt tccataatgg ccagcaggaa
     5521 cgccataccg agcgtcagtg gcacaaaaag gaagtggtac atcgcggtca aggcaaactg
     5581 taagcgcgac agttcgacta tatctaacat catgactcct tgctcatcgc atgaagactc
     5641 cgagagtgaa ccccgttaga aagggtcaca cgcatgcccc aatacaaaat tatttgctcg
     5701 cctctatcgt tgccatttca tcaaaagaag aaaagacaat gataaaaaag ttacaaatat
     5761 gttaatgaat aaaccaaatt tatcccgtaa ttatattacg ctgcaaaatc cttacaataa
     5821 acaggttttt attgagcaaa tttgcatttt tcgacagtga tcaatttata gcgaaattgt
     5881 cacgatccca ccaatttgat ctacaacaat ttatcgtgtt ttgcagattt ttttcaagaa
     5941 ttaaaaattg atttttatca aaatcaatca gatatgttaa ccgctcgtaa atcatgaatc
     6001 attgatgggt ttgttgttaa taaattgtag caaaataaca cagtaaaact acccacatgg
     6061 aaatatatag ataaaaaacc agtattttat ttaacagaac cgccttatcg actttttata
     6121 atactagtta gttagagtag ctactttgtt gccattttac ataacatatt tttatcaacg
     6181 ttaattgatt gttgtcttta tgagcaacgt actgtaaatc cgtcacttat tgtttcattg
     6241 gtaataatca caagaagaaa tagatacctt aggtatagtc agatggaaca aggattttca
     6301 aaataaattt atatggtatt aatatttccc gatctgtatt caatgattcg ctcaaagatt
     6361 gaaaatcaag agaaattgtt atagcagtga tacgagacaa caaaacggaa tgattgccag
     6421 ccgttagaaa acaccggaca ctctcgtgta aaaagctacc ctgtctatgg atatagcgat
     6481 atcgactcat caagcgtgga ctgaatgata ttcagctcca tatgggcggc aacctggagg
     6541 ataaacatga tttcgccgtt ggaatcaagg ttgttctgca atatctacca gactgcttca
     6601 atttatctgt tttggaagtg caataatctt aatttaacta tttgaagatg atgatattgt
     6661 cagatgccag aaatttagta atctggagaa ccgtgtctat gatcactaaa tattaaagta
     6721 atagtcgtca gtaacacatc gagtgatata acgtattgac acctaatcat ataaaaacag
     6781 atcgtaatta agcagcataa gaatatgtct tattatcatt aaaatacatt ctatttccat
     6841 catccttaag ataataaaac agtgagtgat ggataatttc accccaaaaa aaagcaagca
     6901 tataaaatta aaaaacatga ctccactttc atttttatga aatggcatcg tgaagaggcg
     6961 ccagccaatt ataaagatct tgctcctcaa aaaatgaaac aactcagcct gagataatat
     7021 ttttgaccga agttaacatt aaaaatggtt aatagtttgc gcctctcaca caggtccagg
     7081 caactgcgta acaggcaaat caaattttcg taaacagtgg gcatcatcag atgcccacaa
     7141 aatacagctg atttacattt tcgtctttac acgtgcaata gcttcttcat aagaaggctt
     7201 atttttttcc gtatacgcca gttgataatg ctgcaatgct tcagcattct ggcccgaggt
     7261 ttcataaatt ttggcaatgt tataatagga gttggcgcgc gttgtcgccg catttacccc
     7321 actcgctaac gagatcgctt tacgatttgc ccaaattgct tccgctatgt tgccattttt
     7381 ctgatacgcc agacccaggt tactaaatgc ctgtccgtaa ttgccgtcta attctgttgc
     7441 ctgttggaag agttgaatgg cttgctcaag ttgaccggtt ttataaacag cttcaccttc
     7501 gcgattatat tttcttgcca gttgagtatc tccactgttt tgcatcgcag gcgaagccgg
     7561 agctgaagag tccgtcgcag gcattatcac agtggctaaa tccctgacgt ctaatgtggt
     7621 gccgttaaaa ttggcgctgg taacagagtt gatatcttca aactcgccgt ttggattgag
     7681 tttaaacacg gtccagatgt tccctcgttt tcctgcaggg acactataac tacgtaccag
     7741 ggagctccct acataaacaa acacttttgc cttactggca gagagataat tactgttggg
     7801 cagcccttta ttgctatagt cctgcacggc atagatgtaa ctttcaccaa aatgcttttt
     7861 gctgatagtg acagtttctg gtccatagct atccgtatca tcaacatcca gattggcatc
     7921 agttccctct ttactatcaa aatagatatg tccgccaggg aagatcaaat gcgaatcaag
     7981 atcaaaaggc ttttcgcccc agctcaaaac tacacgcatg ccatccagat tcgtcatcac
     8041 cggactgata gcataagtca tgccagcgca cggacatttg accaccagat tggaataccc
     8101 ctcttttttg acgattaata gagcatcttt attatcagca aatgaagtcc ccaaactaat
     8161 gctgcccgaa gtatttgtga taccagaaac agattgtgca ccattgcgtt gcagcgtcac
     8221 cgatgcccct tcaatgcgtt tatctttcac tgtcgcactt aaaatatcaa tgcttacatc
     8281 ggcggcataa gcacctgcat tcatgcccaa cagcgcgaga gcaactggca aaacaatttt
     8341 cttcatgtat aaatcctttt tttaatgaat gtaaggtgga aatttcccag ttattattat
     8401 cgtgttaaaa ggtgaaaaaa aagaaataag tacacttttc agattaacac ccactcacct
     8461 tgaaacaaaa aggccatccg gagatgacct gaactttctg agaaacgctg ttttttcatg
     8521 tggtttgctt tattacacac cattcagact attcggtagc taaatgtccg cgactgtccc
     8581 ggtaaaaaga gagctaattc ttttaaaacc tcattttttt ctgtattaaa gcgttcattc
     8641 atcatggttt ctgtacacgt catcaccttc ctgctaaacg cgacggtcgc atcacagctt
     8701 gtcaattcag ccggattaaa cagccgcaat attaattcct gtctgtcttc tgcttttttt
     8761 agcgcgctga tcagacatcc cactggtggc attttcagca aactatagct ttccggcaca
     8821 ttgaatttgg ctttattaag cttcatcgca tcccacggga ttttgttata acactgaact
     8881 ggcgtcagcc atgcgcgtgc ctgctgggct acaccggcag ttacgggagt accgatataa
     8941 ctaaataaac tcagacgaca ggaaaatgat ccgcgtaatt gtgaatcgga cacaggcatt
     9001 ttaattcctg aaggacgccc tggccttaaa agtaaatctt cttttcccag taatcccaca
     9061 ccacgcaaca acgtaatagc aaaggtttta ttctcttctc caatgacttc aaattcacgt
     9121 aatccttcgc taaaaacggc tatgccgtta cgcccttcct gtaagacagc atagttgagc
     9181 atattccata ccggaaccgg cgcttctttc cagccttctt gctgccagac attcattgcg
     9241 caatccttca ctggccgcgt caatgaacca aactgcgtat ccgcaagaac aacatctgtg
     9301 ttaaaaggcg tgggaatcaa tacacgaata cggtgatcat cggcctggtt atcaagatta
     9361 atatccgcat caatgcgtct gctgttatgg ctaagagtga tcaccgtctc cacccctacc
     9421 ctgccagaac attgctttgc gcgacgctct gacagattac gcggcaccgc tatttcatag
     9481 cgaattatgg ccctactctg ccaggcttca tgaataatat cgtattgcgg tttcgcattc
     9541 gctgaggtaa tggcccactc ttcttttgct ggcgaataat catattcatc cccatcatcg
     9601 gaaccttctt caatttgaaa cacccggtca tagcgcacgc cactatcttt atcaaccaga
     9661 cgaagtgaac catcctcatt gagtgcaatt tgccagaaag cattttccag tattccctct
     9721 gttttacttt ttggcgtgac cacattgcca agctgattcg cttctatata gagcgtgcga
     9781 taccccatag aagggacaat ttggctgatc tgaatatcaa actccataaa gggatcataa
     9841 ttgccgtaat gaactatttg ccgatcaata aggccgggat cgatctcacg ggcatgtcga
     9901 ataaaatatg gcacaggctg accgcgaccg tctcgcaaat taaactggct accgcgcagt
     9961 cgaacagttg tgttgataac ttcttcacgc ggccagggca tcaggttaaa caggacgagt
    10021 ttgtcggcgt cgctctgcgg catgttgtct gctattttgc gcatatagaa ccgaattaga
    10081 ttatccgcca tgtcttctgc cagttcgaag cgggcgacaa tctcgcgatg aactttatca
    10141 ctgcagcagc agccgatgct gtcatgggcg tggtttttta aaatttcttt ccacatcttc
    10201 tccagcaagc cgtggtgata atcaaaacct aaagtccagg ccagcgttgc caacggttcc
    10261 agcagattaa caatcttatt ttcaatgcgt gcgtgggcaa ttttgatatc catgcgcgtg
    10321 gaaccgatgg tgcgatgcac gcgcatatat ttgccatcga tgaattcacc tttcaggatg
    10381 gccagacttt cacgctgcgc ttcaatctgc tcgaatacct cttcaaagcg gctcatcaca
    10441 aactttcgtt gaggataaat ttcgcgcagt ttctccatca cttcgaagat attttgctgc
    10501 aagggcatct ggtcatgacc attcggcaat aaaatttctt tggttactga cgctttttcc
    10561 agcacgtcaa aataactgtc gaggcgttta cgtaatccat tttcgtccgc aggtaagtac
    10621 ttaccgatgg cgtagcccag cggcagcacc tgcgccgtca cttcgctacc gtcactgctt
    10681 tgccacaaaa actcggtttt atcagtaccg tggcgctcag aacatccgcg ccagaacatg
    10741 gtgcgggtaa tgccaaatcc attgtatata tgtggcagtt gcccggacat gccaaaggaa
    10801 tccggtaaat aacctatttt catcggctcg ccaaacgcga ggcagtcacg cattccgtac
    10861 atcagattac ggactatgga ttcagcagaa acaatcgtgg tatcggtctg ggtataccag
    10921 ggaccgataa ttaatttccc gccctcgacc aacttcttca cacgatcttt gttctccggt
    10981 ttgacagcga aataatcttc gaggatcgcc gtttgcccgt cgagtacgta atatttgtat
    11041 tcgttgtcct gttccagtct gcacaggatc tcttccatat tattgaccag cagaatgcga
    11101 gactcttctg tggtgaaata ccactcccga tcccagtgca tatgcggggt gatgtgaacg
    11161 cgagataccg ctttcatcgt cgtttccttt ttgtttatgg cattacgcca tcagtcagat
    11221 agtttccatg ctttaccgca tgatgccgcc agatcaggag aattgcagtc gagattgcag
    11281 cccccaccaa cgccgcacca aaccaaccaa ttgccgccat aacaccaccc gcgccattat
    11341 catgaagtaa aaagagcgag aaaatgccgg caccgggtgt cgaaaggccg atattcatcg
    11401 caccgacgat agcgcccgtt accatagatc ccagcacaaa cgaaccaata acccgcagcg
    11461 gatcttcaat cgccatcggg atcgcccctt cggtgatacc tgccaatcct aacagccagg
    11521 tggatttccc ggtttcaatt tcaaactctt taaacaggcg cggtgcgagc atcgtggaag
    11581 cggttacggt aaatgccgaa accattttga cggaggcgaa aatggcatac gggccgtaaa
    11641 cgccgttcgc cattgccccc agacagaatg cataagcggc tttgttcact ggcccaccaa
    11701 ggtcaaagga acacataaaa ccgagaatgg cgcccaacaa cagtgcgtta tttcctgaca
    11761 gaccgttcag ccaggcggta agcgagttat tgatccatgc gacaggttcc cctactacaa
    11821 acagcatcag actacccgcc cccaacgtac cgagcaccgg gtagagatag aaagtcagga
    11881 atccgttgaa tttactgcta agacgtagat gatttttcac ccagcgcatc agataaccgg
    11941 ctatcaatcc gccaacgacc gcgccgagaa acccggaacc aatcatgttg gcggcaagcc
    12001 ctgccgcaaa gcctggcgct aacgccggtt tatcagccag tgaataggcg gtataggctg
    12061 cgagcaccgg taccatcaaa atcccgagca tcccgccgcc cagcttgcgg tacatccaca
    12121 accaggagtt ttcttcatta aacaaatctt gtagcccgaa gatttgcgac agtaataccg
    12181 cgaccgccag caccgtgcca cccgcgacaa tcagcggcac ggcgaaagag atcccgctca
    12241 acagtgcctg cttcagctcc gttttgacac ttttcaccgg ttgcgtatct tgctgtacgg
    12301 tacgcgtctc atcgctacgc ttgagggtaa gcgcttgttg aatcaacgct tctgcatggc
    12361 gaatcggctc ggcaacaggc acagaaagcg cgggaatgcc gttaaaacgc tcgctctcct
    12421 tgatagcgac ttccgccgca aaaatacagg cggttgcact attgagttgc tccgccgtta
    12481 aacgctcttc aatgccgtta gcaccttgct tttcaacgta gatattcacg ccgagtttgc
    12541 gtccggcttt ttccagatat tccgcagcca tgtaggtgtg agcaataccc gccgggcagg
    12601 ccgttacgca gacgatagtt ggcgcataag aaaaagaggc agtatgttgc gcgtccccct
    12661 tgtcatccag cgccgagagc aattcatcgg gcgtcgttgc cgactgaata cgcgccctga
    12721 gctcatcatc cgccaggcgc gtggtcagcg cggtaagcag tttcatatgc gtagtacctg
    12781 cttcattggg aggaatggcc agcaatacca ctaaatcaac cgcttccggg ccatccacgc
    12841 cttcccactg aagcggctcg ctgagtgtgg cgaccgcaaa cgccgcttct tttaccgcag
    12901 cagttttgcc atgcggcacg gccagccctt cacctaaggc ggtcgggccg aggctttcac
    12961 ggcaatacac ttcttccaga aattgctcag tactggaaat tttccccaga gcagcaagac
    13021 gttgagtcaa cgcgtggatg gcctcttcac ggctggtaaa gcgcacattc agacacagcg
    13081 catcgcggtg ggtcagagtc gtcaggttca tcatggttct cacttgatca tttttatagt
    13141 cgcgcaagtg tgcctgataa aacaatacat ttacgtgatc actttcactt acaagatact
    13201 atttgtatta aatttgtatt atttacaaga tgaatttatc gagcataatg gctaaattcg
    13261 tattaatgag atactagaaa tgggacacaa acccttatac cggcagattg ccgatcgcat
    13321 tcgtgagcag attacgtgcg gcgagctaaa acctggcgat gcgttaccca ctgaatcggc
    13381 attacaaaca gagtttggcg tcagccgggt tacggtgcgc caggctttgc gccagttagt
    13441 cgagcagcag atcctcgaaa gcatccaggg cagcgggact tacgtcaaag aagagcgggt
    13501 caattacgat atttttcagt taaccagttt tgatgaaaaa ctgtcggacc gtcacgtcga
    13561 aacacatagt gaagtcctga tatttgaagt aattccggct gacaattttc ttcagcagca
    13621 gctgcaaatt agcgagcagg atcgtgtgtg gcatgtgaag cgcgtgcgct atcgcaagca
    13681 aaagccggtg gcgctggaag aaacctggat gccgcttgca ttattcccgg atctcacctg
    13741 gcaggtcatg gaaaattcga aatatcactt tattgaagaa gtgaagaaga tggttatcga
    13801 tcgtagcgaa caggagataa ttcccctgat gcccacggaa gagatgagcc gtctgcttaa
    13861 tatcagccag actaagccga ttcttgaaaa agtatcgcgt ggatatttag ttgatggcca
    13921 ggtgtttgaa tatagccgca acgcttttaa tactgatgac tataaattta ccctgatagc
    13981 gcagcgaaaa tcgccgcgat aagcataaaa aaggccatca taagatggcc aaccatgtcg
    14041 aaaccgacag cccttcgccc ttcctgtagg gggaagcggc gagggctatt tcttattaca
    14101 gatatttatt tcagaacagt tttcagtgct tcaccgatat cagccaggct gcgaacggtt
    14161 ttcacgcctg cggcttccag agcagcgaat ttctcatccg cagtaccttt accaccggca
    14221 atgatggcac ccgcgtggcc catacgtttg cctttcggcg cagtcacacc agcgatgtaa
    14281 cccacaactg gcttggtgac gtgctctttg atgtacgcag ccgcttcttc ttcagcgcta
    14341 ccgccgatct caccgatcat cacgatcgct tcagtctgcg gatctttttc gaacatttcg
    14401 agaatatcga taaagttaga gccagggatc gggtcgccgc cgataccaac acaggtcgac
    14461 tgaccgaaac cgtaatccgt ggtctgttta accgcttcat aggtcagcgt accggaacgg
    14521 gaaacgatac ccactttacc tggtttgtga atgtgacccg gctggatacc gattttgcat
    14581 tcccccgggg tgataacgcc tgggcagttc gggccgatca tacgaacgcc tgcttcatcc
    14641 agtttcactt tcaccgtcag catatccagc gtcgggatgc cttcagtgat ggtgataatc
    14701 agtttgatgc ctgcatcgat agcttccaga atggagtctt tgcagaacgg tgctggtacg
    14761 tagataacag aggcggtagc gccagtggca gcaacagctt cacgcacggt gttaaacacc
    14821 ggcaggccga ggtgggtagt accgccttta cctggggtta cgccgccaac cattttagtg
    14881 ccgtatgcaa tggcctgttc agagtggaaa gtcccctggc taccagtaaa gccctggcag
    14941 ataaccttgg tgtttttatc aattaaaatg gacattattt cccctccact gcggcaacaa
    15001 cctgctgagc tgcatccgtc agaccttttg ctgcaataat attcaggccg ctgtcagcca
    15061 gtttcttcgc accgagttcg gcgttgttac cttccagacg taccacgacc ggtacgttaa
    15121 cacccacttc tgctaccgcg ccgatgatac cgtcagcgat caggtcgcaa cgaacgatac
    15181 cgccgaagat gttaaccaga acggctttca ctttgtcgtc agagaggatg attttgaacg
    15241 cttcggttac acgttctttg gttgcgccac cgccaacgtc caggaagtta gccggttcgc
    15301 cgccgtgcag tttaacgatg tccatcgtac ccatcgccag acctgcgccg ttaaccatac
    15361 aaccgatgtt accgtccagc gcaacgtagt tcagttccca ctgtgcagcc tgtgcttcac
    15421 gcggatcttc ctgcgactgg tcacgcattt cacgcagatc aggctggcgg aacagtgcgt
    15481 tgccatcagc gcccagtttg ccgtcgaggc aaatcagatc gccctgtttg gtaataacca
    15541 gcgggttgat ttcgataagc gcaaggtcgc gctccaggaa aatggtcgcc aggcccatga
    15601 agattttggt gaactgctga accagtttac cttccagacc cagtttaaac gccagctcgc
    15661 gtccctgata cggcatcggg ccagtcagcg gatcaagcgc aactttgtgg atcaggtgcg
    15721 gagtttcttc cgccactttt tcgatttcca cgccgccttc ggtggaggcc ataaagacca
    15781 cgcgacggga actacggtca acaacggcac cgagatacag ctctttagcg atatcggtcg
    15841 ctgcttcaac cagaatctgg ttaaccggtt ggccattggc atctgtttga tacgttacca
    15901 gacgcttgcc cagccagttt tctgcaaaag cacggatgtc ttctttgctg tttacaactt
    15961 tcacaccgcc cgctttaccg cggccaccag cgtgaacctg acatttcact acccacggac
    16021 cggcaccgat ttttgaagcg gcttcttctg cttcgcgtgg agtagtacag gcataaccca
    16081 ccggtgctgg taagccatag cgggcaaaaa gttgttttgc ctgatattca tgtaagttca
    16141 tgtgttctgt ccatccttca gtaatcgtta tcttttaaac cgtagaccga ccccctatcc
    16201 acgtcggtct acagtgcagg tgaagcttaa actactacac gtccagcagc agacgcgtcg
    16261 gatcttccag caactctttg atcgttacca ggaagcccac ggattcgcga ccatcgatca
    16321 aacggtgatc gtaggacagc gccaggtaca tcatcggcag gatctcaacc tggccattca
    16381 ccgccatcgg acgatctttg atagcgtgca tacccagaat tgcgctctgc ggcgggttga
    16441 tgataggcgt agacatcagg gaaccgaaca caccaccgtt ggtgatggta aagttaccac
    16501 cagtcagatc ttcaaccgtc agcttgccgt cacggccttt aactgccagc tctttaattt
    16561 tcttctcgat gtctgccatg ccgagggtat cgacatcacg cagaaccggc gtcaccaggc
    16621 cgcgcggcgt agaaaccgcc atactgacgt cgaaatagtt gtggtagacc acatcatcgc
    16681 cgtcgataga cgcattcact tccgggtaac gtttcagggc ttcaaccacc gctttcacgt
    16741 agaaggacat aaagcccaga cggatgccgt ggcgtttttc aaacgcttca ccgtactgct
    16801 tacgcagatc cataatcggc ttcatgttga cttcgttgaa cgtggtcagc atggcggtgg
    16861 agtttttcgc ttccagcaga cgctctgcca cacgcttacg caggcgagtc atcggcacac
    16921 gtttttcgct acgtgcagcc agggccggtt gcgccgccgg agcagccgct gccggagcag
    16981 actctttcgc cggggctttc gccagatgtt tttccacatc ttcacgggtc agacgaccac
    17041 ccacacccgt gcctttaatg gcgctggcgt cgaggttatg ttcagccagc aggcgacgga
    17101 tcgccgggct taacgcatcg ttgttttgct cttccagaga cgcctgctgg cgttgcgccg
    17161 gagtggacgc tttctcttca gatttggcgc tggtttcttt accggcgctg ttgccttcac
    17221 gcaggcgacc aaggatctga cgagacgtta cggttgtacc ttcatcttcc agaaccgcat
    17281 ccagaatgcc gtctgctgat gccggtactt ccagtaccac tttgtcagtt tcgatttcta
    17341 ccagcacttc atcacgtacg actacgtcgc cgggtttttt atgccaggtt gcgacggtgg
    17401 catcggctac ggattcaggc aggtcaggga ccagaatatc tacgctactc attgtgtatc
    17461 ctttatttat tcgacgttca gcgcgtcatt aaccagatct tgttgctgtt tctggtgaac
    17521 ggacatatac cctaccgccg gagaggcgga ggccgggcgg cctgcataac gcagagaagc
    17581 cccaaacgga atcacttcac ggaaatgatg ctggctgcag taccatgcgc cctggttgag
    17641 cggctcttcc tggcaccaga caaaatcctt gacgtgagca aactgctgca acacttcctg
    17701 catcgcttta tgcgggaacg ggtagagttg ctcgatacgc acaatggcga catcgtgttg
    17761 attgttctta cgacgttgtt ccagcagatc gtaataaacc ttaccagaac acatcactac
    17821 gcgcttcacg cccttcggat caagctcgtc gatttcactg atggctggca ggaaggtgcc
    17881 gttcgccagt tcttcgaggc tggaaaccgc cagcggatga cgcagcaggg atttcggcga
    17941 catcacgacc agtggacgac gcatcccgcg caacgcctga cgacgcagca tgtggtaaac
    18001 ctgtgccggg gtagaaggta cgcaaacctg catgttttgc tcagcgcaaa gttgcagata
    18061 acgttccaga cgcgcggagg agtgctccgg cccctgccct tcgtaaccgt gcggcagcaa
    18121 catcaccagg ccacacatcc ggccccattt ctgttcgcca gaggagatga actggtcgat
    18181 aaccacctgt gcaccgttgg cgaagtcacc gaactgtgct tcccagatgg tcagggtgcg
    18241 tggttctgcg gtggcataac cgtattcaaa cgccagtacg gcttcttcag acagtacaga
    18301 gtcccagacg cggaacgcgc cctggccgtt atggatatgt tgcagcggcg tgtaagtgga
    18361 accgttagac tggttgtgga tcaccgcgtg gcggtggaag aaggtaccgc gaccggagtc
    18421 ttcacccgac aggcgaaccg gaatgccttc gtcaaccaac gtggcgtaag cgaggttttc
    18481 cgcgccgccc cagtcgaaca gtttctcacc ggctgccatc gcctggcgat cgccataaat
    18541 tttggcaacg cgagactgca tttcaaccgc ttccggcacc gtgctgatgc gtttagccag
    18601 ttcctgcagg cgcttcatct caactttgtt cgggtactct tcgtcccatt cgtggttgag
    18661 gtacggcgac caggtgaaag agtgcatgtt catcggacgc cactctgcta caacgcaatc
    18721 gccagcatcc agcgcatcgc ggtacaggtt aaccatctcg gtggcatctt ccagcgtcgc
    18781 gactttttcc tgctccagct tgtcagcgta gattttgcgc ggcgtcggat gttttttgat
    18841 tttctgatac atcagcggct gggttgcgct cggctcgtcg gcttcgttgt ggccgtgacg
    18901 gcggtagcat accaggtcga tgaagacatc acgtttaaag gtgttacgga aatcgagcgc
    18961 cagacgggtc acaaaggcaa cggcttccgg atcatccgca ttaacgtgga aaatcggtgc
    19021 ctgaaccatc ttaccgatat cagtacagta cggcgtcgaa cgggcatcca gcgggttaga
    19081 ggtggtgaag ccaacctggt tgttgataac gatacgtacc gtaccgccaa cttcataacc
    19141 acgcgctttc gacatgttca gggtttcctg aactacgccc tgcccggtca ctgcggcgtc
    19201 accatgaatg gtgattggca gcactttgtt gctgctcggc tcatcaagtc tgtccagacg
    19261 ggcacgaaca gaaccgataa cgaccgggct tacaatctca aggtgagacg ggttaaacgc
    19321 cagcgccagg tgcaccaggc cgccatcggt ctggaagtca gacgagaagc ccatgtggta
    19381 tttcacgtcg cccgtgccga ggtgttcttt atgtttaccg gcaaactcgt cgaacaagtc
    19441 ttgcggtttt ttacccagca cgttcaccag cacgttcaga cgaccacggt gcgccatccc
    19501 gagaaccact tcgcgggtgc cgctgttgcc agcgtggcgg atcatctctt taagcatcgg
    19561 gattaacgcg tcaccgcctt ccagcgagaa gcgttttgcg ccagggaatt ttgcgccaag
    19621 gtaacgttca aggccttcag cggcggtcag ttcgcttaag aagcgttttt tctcttcgct
    19681 attgaaagtc gcgcgaccag actcgatacg ctgttggatc cagcgttttt cttcggtgct
    19741 ggtaatgtgc atatactcgg caccaatcgg gccacagtag gtttgcttga gggcttccag
    19801 cagctcgccg agtttcatgg tttctttgcc gctggcaaat gaaccgacgt tgaaggtctc
    19861 ctggaagtct gcttcggtca gatcgtggaa agacggatcc agatcggcca ctttatcttg
    19921 ctgccacagt cccagcggat cgagattcgc atgctggtga ccacggaagc ggtatgcgtt
    19981 aatgagctgc aggactttaa cctgcttcac attggtgtca gggtcggaga tcgttgaaga
    20041 gtaacgtgaa gcgtctttcg ccaggcggcg gaaatattca cgcgtttgag agtggaattg
    20101 atccggtttg actcccgtac caggtaactg ctggaacgtc gaacgccagt tagcgtcaac
    20161 cgagtcagga tcggttaaga agtcttcata gagctgttct atccagctct ggtttgcgcc
    20221 agagaggtaa gaagagtcca accaggcttt caaagcgctg ttctgcatcg tgatccctta
    20281 agcatctttt ttatgcttac ttcgccgtgg atactaccac gcacatttca tatctgatgt
    20341 gcgtgccggg gttcacttgt tgcggacttg tcgtgttttc tgcgtccgct aaggaacctt
    20401 taaaaactgt cttagtgtca ggggcagttt ttaaagattt cctgcatttc ttttgtaggc
    20461 cggataaggc attcacgccg catccggcgc tgtttgcctg atgcgacgct tgcgcgtctt
    20521 atcaggccta cggtttctgc atttcttttg taggccggat aaggcgttca cgccgcatcc
    20581 ggcactggtt gcctgatgcg acgcttgtgc gtcttatcag gcctacggtt tacgcattac
    20641 gttgcaacaa catcgacttg atatggccga tggcgcgcgt cgggttcagc cccttcggac
    20701 atacactgac gcagttcatg atgctgtgac agcggaatac actgaatgca tcgctcaaac
    20761 cgtcgaggcg gctgtcagtc tcggtatcac ggctatcgat caggaaacga tatgccgcta
    20821 acaagcctgc cggaccgata aacttatcgg gattccacca gaaagacgga caagaggttg
    20881 aacaacatgc gcagagaata cattcataca acccgtcgag tttttcgcgc tgctctggca
    20941 tctgtaaatg ctcgcgagct ggcggatttt gtccattatt caacaggtaa ggcttaattt
    21001 tctcatattg cgcatagaat tgtcccatgt ctaccaccaa atcgcggatc accggtaaac
    21061 ctggcagcgg acgaatcaca atcttcttgc ccggctggtt gagtgccgaa atcggggtaa
    21121 tacaggccag accattctta ccgttcatgt tcagaccgtc ggaaccgcac acaccttcac
    21181 ggcaggagcg gcggaacgac aggctgggat ctttctcttt cagctgaata agcgcatcca
    21241 gcagcatcat gtcgcgacct tcttccgctt ccagggtgta atcctgcata cgcggagcat
    21301 catcaacatc cgggttatag cgataaattg aaaactcgag tctcattttc ctgtctccgc
    21361 attagtaagt acgaatcttc ggcgggaatg ccgggcgcag tttcggttcc atgttgacgc
    21421 ttcggcgcgt catggattcc gactctggca gatacaggga gtggcacagc cagttttcat
    21481 catcacgatc cgggaagtcg aagcggctat gcgcgccacg gctttcggta cggaagttgg
    21541 cagaaacagc cgttgcatac gccgtttcca tcaggttatc cagttccagg cactcaacgc
    21601 gctgggtgtt gaactcgctg gaagtgtcat ccagacgggc atttttcaga cgctcgcgga
    21661 taactttcaa ctgctcaagc cctttcgcca tcgcatcacc ttcacggaag accgagaagt
    21721 tatgctgcat acattcttgc agtgctttac ggatcgccac cggatcttca ccgttacggt
    21781 tattgttcca gcggttcagg cgatccagag acgcttctac atcagactcg ctggcatcgc
    21841 gcagtgcgcc ctgctcggcg atagactctt gcagatgcag acctgccgca cgaccaaata
    21901 ccaccaggtc cagcagcgag ttgccgccca gacggttagc gccgtgtacc gatacacaag
    21961 cgatttcacc aacggcaaac agccccggaa caaccacatc ttcgcctttc tcattcaccg
    22021 tcagcgcctg accggtcact ttggtcggaa taccgcccat catgtagtga caggttggga
    22081 taaccggaat cggctctttc accggatcga cgtgagcgaa ggtacgggag agttccagaa
    22141 tacccggcag acgggattcg agaacttctt tccccagatg gtcaagtttc agttttgcgt
    22201 gtggccccca cggaccatca cagccgcgac cttcacggat ttcgatcatg atggaacgcg
    22261 ccaccacgtc acggcccgcc aggtctttgg cgttcggcgc ataacgctcc ataaagcgtt
    22321 cgccatgttt gttcagcaga taaccgcctt caccacggca cccttcggtg accagtacgc
    22381 ccgcaccggc aataccggtc gggtggaact gccacatttc catatcctgc accggtacgc
    22441 ctgcacggat agccatgccg acaccgtcgc cagtgttaat gtgggcgttg gtggtggact
    22501 gataaatacg ccctgccccg ccagtcgcca gcactgtcgc gcgagcttta aagtaaacca
    22561 cttcaccagt ttcgatgcac agtgcggtac aaccgaccac tgcgccatcc tggtttttca
    22621 ccagatccag cgcataccac tcggagaaaa tggtggtgtg gtttttcagg ttctgctgat
    22681 aaagcgtgtg caacagtgcg tgaccggtac ggtcagctgc cgccgcagta cgtgccgcct
    22741 gctcgccgcc gaagtttttc gactgaccgc caaacggacg ttgatagata cgaccatcat
    22801 caagacgcga gaacggcagg cccatatgtt ccagttccag aatcgcttcc ggcccggttt
    22861 tacacatata ttcaatcgcg tcctggtcac cgatatagtc cgaccctttt acggtgtcgt
    22921 acatatgcca ttcccagtta tcttcatggg tattacccag cgcaacggta ataccacctt
    22981 gcgcagaaac ggtatgggaa cgggtcggga agaccttaga gagcagcgca caggtctggc
    23041 cactctggga aatttgcagc gccgcgcgca tacctgcgcc gccagcacca atcacaactg
    23101 catcaaattc tctgactggc aatttcatca cacaccccac accacaacga atccataaat
    23161 cacgtaaacc accagtgcaa cgacaatcac cagttgcagc atcaggcgca aggccagcgg
    23221 tttaacgtag tcggtcaaca cctgccacat gccgatccag gcatggatca agatagaaaa
    23281 cagcgccagc agggtgaaca ctttggtgaa cgcagaggcg aagaaaccaa tccagacttc
    23341 atatgtcagc tcgccactgg tagcgaaaaa accgaccata taaatgatgt agagcgtcag
    23401 gacgatagcg gtagcacgaa cgaggatgaa atcatgtacg ccattgcgtc ctaatgcgga
    23461 ggcgttgctt accatacgag gactcctgcg agaagtgaaa gcacgacagt aataacaaag
    23521 gagattttgg cggagcgttt acccgcttcg aatgtttctt ccagatagcc aaaatccatc
    23581 atcatgtggc gaatacctac gacgacgtga tatgccagag cggtaaggat gccccacatg
    23641 ataaatttga cgaagaagct gcccataatc gcggaagctt gctcgaaacc ttcaggggaa
    23701 gagaggctgg tacccagaag ccacagcagg atgcccactg caacaaaggt gatcacaccg
    23761 gaaacgcgat ggagaatgga cgctatcgcc gtgacgggga accggatggt ctgtaggtcc
    23821 agattaacag gtctttgttt tttcacattt cttatcatga ataacgccca catgctgttc
    23881 ttattattcc ctggggacta cgggcacaga ggttaacttt ctgttaccag gagacgtcgg
    23941 gatttccttc ctccggtctg cttgcgggtc agacagcgtc ctttctataa ctgcgcgtca
    24001 tgcaaaacac tgcttccaga tgcgaaaacg acacgttaca acgctgggtg gctcgggatt
    24061 gcagggtgtt ccggagacct ggcggcagta taggctgttc acaaaatcat tacaattaac
    24121 ctacatatag tttgtcgggt tttatcccga acagtgatct gcgtcacgat aacaacattt
    24181 atttaatttt taatcatcta atttgacaat cattcaacaa agttgttaca aacattacta
    24241 ggaaaagcat ataatgcgta aaagttatga agtcggtatt tcacctaaga ttaacttatg
    24301 taacagtgtg gaagtattga ccaattcatt cgggacagtt attagtggta gacaagttta
    24361 ataattcgga ttgctaagta cttgattcgc catttattcg tcatcaatag atcctttacc
    24421 tgcaagcgcc cagagctctg tacccaggtt ttcccctctt tcacagagcg gcgagccaaa
    24481 taacaaacgg gtaaagccag gttgatgtgc gaaggcaaat ttaagttccg gcagtcttac
    24541 gcaataaggc gctaaggaga ccttaaatgg ctgatacaaa agcaaaactc accctcaacg
    24601 gggacacagc tgttgaactg gatgtgctga aaggcacgct gggtcaagat gttattgata
    24661 tccgtactct cggttcaaaa ggtgtgttca cctttgaccc aggcttcact tcaaccgcat
    24721 cctgcgaatc taaaattact tttattgatg gtgatgaagg tattttgctg caccgcggtt
    24781 tcccgatcga tcagctggcg accgattcta actacctgga agtttgttac atcctgctga
    24841 atggtgaaaa accgactcag gaacagtatg acgaatttaa aactacggtg acccgtcata
    24901 ccatgatcca cgagcagatt acccgtctgt tccatgcttt ccgtcgcgac tcgcatccaa
    24961 tggcagtcat gtgtggtatt accggcgcgc tggcagcgtt ctatcacgac tcgctggatg
    25021 ttaacaatcc tcgtcatcgt gaaattgccg cgttccgcct gctgtcaaaa atgccgacca
    25081 tggccgcgat gtgttacaag tattccattg gtcagccatt tgtttacccg cgcaacgatc
    25141 tctcctacgc cggtaacttc ctgaatatga tgttctccac accgtgcgaa ccgtatgaag
    25201 ttaatccgat tctggaacgt gctatggacc gtattctgat cctgcacgct gaccatgaac
    25261 agaacgcctc cacctccacc gtgcgtaccg ctggctcttc gggtgcgaac ccgtttgcct
    25321 gtatcgcagc aggtattgct tcactgtggg gacctgcgca cggtggtgct aacgaagcgg
    25381 cgctgaaaat gctggaagaa atcagctccg ttaaacacat tccggaattt gttcgtcgtg
    25441 cgaaagacaa aaatgattct ttccgcctga tgggcttcgg tcatcgcgtg tacaaaaact
    25501 acgacccgcg cgccaccgta atgcgtgaaa cctgccatga agtgctgaaa gagctgggca
    25561 ccaaagatga cctgctggaa gtggctatgg agctggaaaa catcgcgctg aacgacccgt
    25621 actttatcga gaaaaaactg tacccgaacg tcgatttcta ctctggtatc atcctgaaag
    25681 cgatgggtat tccgtcttct atgttcaccg tgatcttcgc tatggcacgt acggttggct
    25741 ggatcgccca ctggagcgaa atgcacagtg acggtatgaa gattgcccgt ccgcgtcagc
    25801 tgtataccgg ctacgcgcag cgtgatttta agtcggatat taagaagtaa aaatgacacc
    25861 gacaaaaccc tgcgtggaca cgcagggttt ttaattctac accagcagca aagatattgc
    25921 cggaatatag gtaatgacca acagaagtaa aataagactg atcagtaatg gcaccgcttc
    25981 acgcataaat tgcccgacag aaacctgtac ggtattacat accagcagca tcaccgttcc
    26041 gacaggtggt gataacgttc ctaacgataa gttgaggatc ataatgatgc caaaatgcac
    26101 cggatcaatg ccaaaatgag ccaccacggg tttaagtaat gggactaata tcagcagaat
    26161 ggcactacct tcaaggaaca tgccaagcac cagcagcaat agattgataa tcaataaaaa
    26221 gacgtattta ttatcggtca gagaagttac aaactccgca accgtgatac ctgcccgctc
    26281 aagggaaaat atccagccca gcgcggcact cgccataatg attaacatga ccgatgccgt
    26341 ggaacgcgcc gtctcagaga gtgctgtaaa tacatggctg attttcagtt cgcgataaat
    26401 tacaaaacca ataaacatta ccaataatac tgctaccgct ccggcttccg ttggcgtaaa
    26461 gatatttgcc cgaataccac cgataaccgc aacaattaag aacagtgctg gccaggcctg
    26521 caccagcgcc actgacactt ctttcggttt tggccagtgt tcgctggaag gttttaaacc
    26581 gcgacgaata gccaccaacc atacggtaac gatcaacatg gcggagcaca gcagacctgg
    26641 caggatcccg gccataaaca tggagccgat ggagacatcc gccaccagtc cgtaaaggat
    26701 cagtgcaata cccggtggaa taattggtgt aatcagcgaa ccacttgccg ttatcgccgc
    26761 cgcaaagcca cgggaataac ctttctgttc catttccggc accatcatgc gcgataacat
    26821 tgcggcatcc gccagatttg aggcactgac accgcccatc atggtactga ccagaatatt
    26881 agccccaccc aggccaccgc gcattctgcc aatcaacacg ttggcaattt gcaaaatacg
    26941 cgcggcaata ccggtatagc tcattaacgt gcctaataag ataaaaaacg gaatagctaa
    27001 cagcgaaggg gtttgcgtcg tggcaatcaa acgctgaatt gccaccatta acggcacatt
    27061 tgaatagcaa aggaagtagg tcagaatgcc gcaaaacatc gccagccata ccggcatatt
    27121 gataaataaa cagacgaaca taagcggaat gatcatcagc cagttatcca gccagcttcc
    27181 cgccagtaat tcactcaatg ctgtcattat tcaccttctt tgcgtggcgt tttcttgatc
    27241 agttgtaagg cagtaaaaca ggcgacaccg atagcgccaa ccgtgacggc aatatcgatc
    27301 caaaaccagg atatttttaa tatttgcgtg gttttaaagg ctgtcccggc agctaatttc
    27361 catgctgacc aggccatgac caccagcaaa ataatagaca tcagagagac taaaaacgct
    27421 aatatacgtt gcccgcgtga agtaagtgca tcggctaaaa atggaatcga taaatgggta
    27481 ttatctcgtt cagcaacaac cgcaccaaac atgactaccc aaatcattaa taaaccggaa
    27541 acctcttctg tccactgtaa tggcatatga aaacagtaac gcattattac cgcagcaatg
    27601 gtcatgatta ccaatataaa gagcgttaat accgcagcaa cttcaatcat tttccctaaa
    27661 agacgcataa acacctctgc tcttaacggt cggtgccgaa acaccgacca gtccttatgc
    27721 catgaagtta tttcagctgt tgctgaatag tgtcatacaa accaggggtc cattccggga
    27781 attgttgata gacttttaag gctttttctt tgaaaggggc gacgtcagga tagatgattt
    27841 ccacgccctg ctcctgcatg gttttcaaca ttgtcgcatc ctgctcagtg gtaattttct
    27901 ggctatataa accagcttca tacgctgtct ggtgaataat atctaactgc gcaggtgtca
    27961 gggtactgaa aaacgcttcg ccacccaacc ataatgatgt attggtcaga tagttcacca
    28021 ttgacagata tttcgcctgc tcatgcagct tttgcccata gagaacagaa accgggtttt
    28081 ccacaccatc gatcatcccc tgagtcagcg ccggataaac atctcccagc ggcattggtg
    28141 ttggggttgc gcccatcgct tcgatagctt taatctgcat gacgttattc ggcacgcgga
    28201 tcttcatccc tttcaagtct tcaggtgtac gaatcggttt tttagcaatg atctgcctgg
    28261 taccgtacag atagttgctc atgacaatat gcacaccttt ttcccgtagt ttctgttctt
    28321 tttgtttaaa ccagtcactg gcataaatcg caaacagttt ctgcggatct tcggttaaat
    28381 aaggcccaaa caatattccc aagtctgcat cgtagtcagt taaaaatcct acatcactga
    28441 tggtgataat attcatcccc atcaacgctt gttcagtaat atcttgttta gaacctaact
    28501 gtgaacttgg gtaaagttcg aaaacaatat ctccattgct ttttttcttc acaagttctg
    28561 cccagtgctt cactactgta tccgctggct cgccggggtt actttcatag gcgattttga
    28621 tagttaccgg tgcggcattc agcatcggac taaataaagc taaaagaaat aaaagtggtg
    28681 tcagtaattt tttcattatt attacctgta agagctttat cgattaacgg ggatctgccc
    28741 gacagactgc acttttgctg taatcaaatg ctttatacgt taaaacaaac tcctgatgtt
    28801 ccagtcgttc tgcggcacaa tattgaccgt tggcgacatg ttcaatcacc tgcataatat
    28861 cgtctgcaat atcgtcgagc gttgcgcctt cgctaattac acgaccggca ttaacgtcca
    28921 tatcgtcaga taaatgctcc cacgtctgcg ggttattaca cactttaata ataggagcga
    28981 tcactgaacc aataactgaa ccgcgacctg tggtaaataa caccatatga cagccagagg
    29041 cgataagttc cagtgcttct gaggaatcgt taatattcgg atacccaaaa cgaggttcac
    29101 catcaggcac cacgtccatc aaccaaagcc caggaaaggg cgtttgttgc gtcggcaaaa
    29161 taacgccagc aatcagcgca tcgcccgact tggtataagc cccaagggat ttttcttcct
    29221 gagtggttaa gccgccttca gcattaccgt tagaaaaact ccccagcccc atcaaactgt
    29281 aataacgttc ggcttttgtc attgccactt cgatggcatc acgtgcctgc gaactagccg
    29341 cgcgcgacat catatgctgc tcacaaccaa gcaactcacc gctttcttca aaaatacagg
    29401 tagccccttt ctccagcagt tggtcaaagg cacgtcctac tgccgggtta cccgtgatac
    29461 cactggtgcc atcggagcca ccgcagatag taccaaccac caggtcgctc cagttcagga
    29521 tacaacgcgg tgtatccgca agctgttcca gcatttcagc gaccaactgc ttacccagag
    29581 taatggtgtt ggtcgtgcct ttattttcct gaatgaccag cgtatggcac ggtcgcccac
    29641 tttctcgtac ttcttgctcc agccgacggc gatcgaaatt ctcgcacccc agcgaaataa
    29701 tcagtacacc acctacgttg ctatgagtcg ccagattttt caccagccga tagccataat
    29761 cgctgggata acaacctgaa aaaccaaaat actgcacgtc gtgacaagga aatccttcgg
    29821 caatcttttt agcgacatgg ctggcacact ccaccataaa gattacctgc acagtattac
    29881 gaatacctgg tcgaccattt tgccgtacat aaccttccat tatgcttttt cctctgactg
    29941 atagccggca tcatcatgat gaaaaatggc gatggcattg ctggcaagat tatgggaatg
    30001 cacatgttca cccatggcaa tatcgcgagt ggcgtgtccg ataatggcgc cgtatttcag
    30061 aatcgaatca ccattgttca gcgcttcgca ggccagtttg tgccccaggg taacggaact
    30121 acaggccacc atttccccct catcccacca gacaatatcg ccactggcga tgtcattcag
    30181 cgcgactaca cagttatctt tggcatgtag ctttaacgca cgtttgcgca taattcctcc
    30241 gtacatcaga agccgatcaa tgcgccgcca tccaccacca gcacctgacc actgacaaac
    30301 gccgctgcgt ctgaagccag ataaaccgca gcccaaccga tatcctccgg cttgccgaat
    30361 tttttcatcg gggtacgacc caggattttg ttacggcgtt cgtcatcacc ttcaatggcc
    30421 ttacgcaaca ttggtgtatc gatccagcct ggcgcaatac cattgacgcg aatcccatga
    30481 acggcaagct ccgtggtcat accgcgaatc atgccgagat aggctgactt cgctgcgctg
    30541 tagccagtaa ccagaggctg cccaagaaat gaggtcatcg atgcagtaaa aagcacacag
    30601 cctttaccgc gttgtttcat atgcggcacc agcgctttgg ttaacgcaaa tgcgccgact
    30661 acgtgaacgt cgagtactga ctcaaaatca ctgacgctca tctcttcaat cggttttttg
    30721 cagtgattgc ctgcgttatt gaccaggata tcgatagccc cgtgttcgct aataagcaca
    30781 tcaacttttt cctgcgcggc tgcggtatcc ccgacatcca tttgtatcca actggcctgc
    30841 gaccccaatg ttccggcggt cgcttgcgcc agctcgccgt tcaggtcagc aataatgacc
    30901 ttcgccccgc tgactatcat gcatttcgcc attgccagcc ccagcccact ggctgcaccg
    30961 gtgatcaacg cggttttgtt atgtaaagaa aaagcattca tggtgtcgct ccttaaaggt
    31021 caatgaggat tttggtatac gcgccgggat cacttgccca gtcgctaaaa gcgtgatcag
    31081 cctgttccag cgggtagtga gcactcacca gattgctgac cggataacgc ccggactcca
    31141 tcaatgccag cacggcacga aaatccgcca cggtggcatt gcgcgaacca cggatatcca
    31201 gttctttcat caggaactgc gcactctgat aactcactgg ctgtttggcg taaccgacat
    31261 aaaccacacg accgctaaac gccaccaacc ctgtagcctg ttcaatggtt tgttgattac
    31321 ccaccgcttc aatcaccact tccgggccgc gaccgtcatt taacagcacc agttctgccg
    31381 ccacgtcaca ttgctgcgaa ttaagaaaac gttgcgcacc gcattccagg gcaatgttcc
    31441 gcttgcgatc atcaatatcg atagcaatta cgcgcgcccc catggcggat gccgcggcga
    31501 tagcgccaag gccaattacc ccacaaccga taactgcgac ccattcaccc acattaattt
    31561 gcgcacgtct ggccgcatgt agtcccacgg ccagcggttc taccagcgct aactcatcaa
    31621 cacttaaggc attacagaca atgactttat gtgcaggcat cgtcagttgt tgcgccatcc
    31681 ccccctgacg ttgcacacca agagtttggt tgtttttaca ggcgttagga cgaccgctca
    31741 gacaggagct gcacacgcca cactcagtgc aaggcagaac gaccacccgg tcacctggct
    31801 tgatcgcccc tgccatatcg ccagttgcca gcaccgtgcc gccaatttca tgccccggaa
    31861 tacagggata attaaccagc ggatttagtc cccgccaggt attgaggtca gaaccacaca
    31921 gtccgacacg ctcaacattg attagcactt ctcctttacc gcagacaggt tcggggatat
    31981 caacaaatcg cgcctgactt ccctgctcaa tggttaatgc cttcattcat tgctctcctt
    32041 acattacgcc gaaggtttca aaggcctgta ccgtgctcat gccatcactg atggctttgc
    32101 gcacttcact ttcagttgcc actttttcca gggcctgggt aataacttct ttctcaacaa
    32161 cctggggaat aatcagtaat ccgtcacgat caccaaacac gatatcgccc ggattcactc
    32221 gcacgccgtg aaattcaata ggtacgccga agtcgatgac cttgccgcgc ggaccttgat
    32281 cctgtgcgta agtgccatga caaaaagtgg gaaatttcaa ttcaagaatt tcagcagagt
    32341 cacgggcgta accatcgagt accgcacctg ctgctttcag atgcatggca cgggtagaca
    32401 tcaacccgcc ccacaaggca tagcgcagag agctgcccgt agtgatgtaa acatcgttct
    32461 ctttgagggc atccagcgct tcaaacatga tgccaaacgg tttttcgcca atcgccgtct
    32521 tacccgacgt cgatttggtt tcgtaaacgt ccgactccag caccggcatt gcccggcctg
    32581 ccaccaccgt attcacatcc agcggcttga ttgccggaga aacaaactgg tgcatatagc
    32641 ccagcgtgtc gagaatatcg ccaaccacgg cggtaaatag ccgggttttc atcaaagcaa
    32701 aaagttcgtt atcactcttc cacattattt tcgtcctgta agcctgttta acaggtttac
    32761 agggtaagga gaaaaagcgc acaatactgc gaagggcgtc acgaaaaagt tgtgtattta
    32821 ctatttcttc gccactcttt cacacaatat gtctttgatt cgcactgcat ggcgggcgca
    32881 caggcgcagt agtctattga taatcaaggg ttctggagga aaatatgaag gatacagtcc
    32941 cggtattctg gatttcaccg accaggaaaa agtacaacag gagtaaaaat gagtgagagt
    33001 gcgttattga ccagcgtaac gttatcgtca caggtcaaaa atcatattct taatctgatc
    33061 gccgaacaaa aattgacacc ggggatgcca gttcccagtg aagttcagct gattcagaaa
    33121 ttgggtgtca gtcggggtat tgtgcgtgag gcctatcgtt cacttgccgc cctggggatt
    33181 ctggaaacgc acagcggtaa agtgccacga atcaaaaaat ttgatgatga agtgctgcgc
    33241 gtggtgtttg gatttgccct ggcgaccgaa caagtgacaa cagagcaaat tcttcaagta
    33301 cgccgctggc tggagttggg cgttgtggaa gctgctgccc gtaatggcga agaggaagat
    33361 tttgctaacc tacgggctga aatggcaaaa atccgcgaac agttcaatga tgttgaaagc
    33421 tttatcaccc atgatatccg cttccatcag ttacttgccg ttgcctcaaa aaatccgctt
    33481 tttatgatgt tattgcaggc attacatcag cagttgcggc aatccatcca ggagggttta
    33541 aacgcccaaa gcgatcagaa agagtatggc aatcacatca tcacactaca ccagaaaatc
    33601 tgcgatgctg tgtgtgccag ggatgtcgaa acggcgactc aagccatgaa atcacacttc
    33661 gacagcccgg tcagtgcact gatcaataat tcctcgtcat aagacttatc tcagttcaat
    33721 cgtttactct tccctctttt acaaacgaga gggagacaac ggtacttaat acgcccttta
    33781 gccaaaatct gtctttttct tgattaccgc tattttttcg ttgaggcgca ttctttatgc
    33841 tgtatcgata caccaaaggt aagttaaaca gggagtgacg gatgccagtg ctacagtggg
    33901 gaatgttatg tgttctgtca cttctccttt ctattggctt cctcgcttta catctcccgg
    33961 cggcactcct gcttggcccg atgatcgcgg ggatcatctt cagtatgcac ggagtcactc
    34021 tgcaacttcc ccgctccgct tttctcgctg cccaagccat tcttggctgc atgattgcac
    34081 aaaacctcac tggttcgatt ctcaccacgc tggccgtcaa ctggccgatc gtgcttgcga
    34141 ttttactggt gacgctgctt tccagcgcca tcgtgggttg gttattggtg cgctatagct
    34201 cactgcctgg gaataccggg gcctggggtt cttctcctgg cggcgcggcg gcaatggtcg
    34261 caatggcgca agattacggc gcagatattc gcctggtggc gtttatgcaa tatctgcgag
    34321 tgctgttcgt cgcaggagcc gctgttctgg tcacccgcat gatgctgggc gataacgctg
    34381 aagcggttaa ccagcagatc gtctggttcc cgccagtgag cattaatctc ctgcttacga
    34441 ttttgctcgc ggtcgttgcc ggtacggcgg gatgcttgct acgtcttcct tccggcacga
    34501 tgctcatccc gatgctggcg ggcgcagtgc tccagtctgg tcagctcatc acgattgaac
    34561 tcccggaatg gctgctggcg atggcatata tggcaattgg ctggcggatt ggtcttggtt
    34621 tcgataagca aatattactg cgggcattgc gcccgctacc gcaaatcctg ctgtcgattt
    34681 ttgctctgct ggctatttgt gcgggcatgg cgtgggggct gacccggttt atgcatattg
    34741 attttatgac cgcctacctc gccaccagcc ccggcgggct tgataccgtg gcggtcatcg
    34801 ccgcagggag caatgccgat atggcgctca tcattgcgat gcaaaccctg cgcctgttca
    34861 gtattttgct gacggggcct gccatcgcac ggtttatttc aacctatgcg ccgaagcgtt
    34921 cggcctagtg ctggcagcct gggcaccagt aaaacgggcg cgatgacagc gtggttttct
    34981 caatgatgcc gccacagcgt tcgcaaggtt cgccatcacg atgaaaaacc ttaaagcgaa
    35041 acagcgcccc atgatatttg ttttcatcca cctgcccccg cgtagcgtaa gaaagtcgcg
    35101 gaatatccag taacgcgtgt gcgagtgcat ccagttgcgg cgcattgaga tctttcgctt
    35161 tatgatttcc ggtcaaccca acctgccaga ggatctccac ccgcaaataa ttgccaagtc
    35221 ctgccagaaa cgcctgatcg agcagtaatc cagcaaactg acggttacga aagcgcggcg
    35281 acaataatcg ttcctttacc acctccggcg tcagattcgg atccagcaca tcgggaccaa
    35341 cgcgttgtaa aaacggatgc gtggtcagtt gttccggagt caacatctca atatccgagg
    35401 cgctataaag cagaatggtt ttgtcagccg tttgcagttt tacccgcaat actcgcgtgg
    35461 tctgcggctc ttcgccggta tcaaccacgc gccagacgcc gtaaagctga ttatggctgt
    35521 agagcgttaa gtcgttggaa aaatgagtta acaacgcctt accacgcgtt tccacatggg
    35581 taacgtgttg accgataagt cgtgattgat aagattttaa ctgcgggaag gcaaaccaga
    35641 catcagttag tggtttgcct ttgatcgccg cctccaggtt atccgctgca cggcggatct
    35701 ccgggccttc aggcatggtg atatcctttt ttcattcttt attaagcggg gttatgctgc
    35761 gacaacaatc cccttttcag caaatgtagc tcgtaatcgg cgggcgaacg ccagtgcgtg
    35821 ctcgccatcg ccatgtaggc agaccgtttg cgccgtgacc attgcccatt cgccggtgat
    35881 acttttgact ctgccgtgtt gcaccatctc caacgtttgc gccagcgcct gttcttcgtt
    35941 ttcaatcaac gcgcctggct ggcttcgcgg caccagcgaa ccgtctgcct gataaccacg
    36001 atcggcaaac acttcctcgc gcgttaccag gccatatcgt tcgcctgcac gaatcagctc
    36061 gcttcctgcc agcccgacga gaatcaatgc cggatcgcaa gcgtataccg ctctggcgat
    36121 agcgtctgcc agttgtgcct ctttcgccgc ctggttgtat aacatgccgt gcggtttgac
    36181 atgacacatt acgccgcctt gcgcacgggt aatcgctgcc agcgcgccaa tttgatacag
    36241 cgtctgggcg aaaatggttt ctggcggcag ctgcatggcg ctgcgaccaa aattttccct
    36301 gtcgggaaaa ctcgggtgag cgccaatcgc gacaccattt tttattgctt cacgcacgca
    36361 agcctgcatg gtttgcgcat ctcctgcatg aaatccacag gcaatattgg cagaggaaac
    36421 cagcgttaat agctctgcgt cgctggcgca gccttcgccc agatcggcgt tcaggtcaat
    36481 tttcattgtg cagccgccac gctaattgtt cgaaataacg ttgctgatct tgccgcgctt
    36541 tcagtgcctc ttccagtgaa cactggacaa aatgaatcgg ctgaccgagc ggaatttgcg
    36601 ccagatggta catatcagcc tcaatgatac aggcaatacg cgggtaacca ccggtggtct
    36661 gtgcgtcgtt catcaataca atcggctggc cgttatgcgg cacctgcacc acgcccggca
    36721 acaaaccgtg agataacagt tcgcgatcgg tggtgcgttt taaaatttgc ccctgtaagc
    36781 gatagcccat gcggttactt tgcgggctaa gctgccaggg cgaacgccag aatgcatcct
    36841 gcgaggcgcg atcgaactca tgatattccg gccccggcaa ggcgcgaatg cggttgcccc
    36901 agagcagctg tttaacgccc tgcgcttcca taaaatcacg cttcgctttg ccaatcggga
    36961 gtcggtcacc atccctcagt aaacggcctt ccagcccgcc aatccccact ttgagatcgg
    37021 tgctgcatga tcccattacc ggcggaacat caataccacc cgcgaccgcc agataactgc
    37081 gcatcccgtg ctgcgggcgt ttaagcgtta aacgctggcc tgctttcatc ggcaatcgcc
    37141 agccggtcca gacggcatta tcatccagcc gcgcttcgca accggcaccc gtcagagcaa
    37201 accacccatc agtttcgaac tcaaccgtta actgaccgag cgtgatctcc agcgcggggg
    37261 cattggcgtc attacccacc agcaggttag caatgcgtaa cgcaggcata tccagtgcgc
    37321 cacagtggct gataccagac tgacgaaagc cgtgacggcc gccatcctgc acggtggtgt
    37381 acatgcccgc acgaataatc ttcagcatac tccctccttc tgcggtacaa agcgcacgct
    37441 gtctcccgga cgtaataaga tgggttcgtc acacgccgga tcaaacaggc tgagtgaggt
    37501 atgaccaatc aactgccagc cacccggcgt tgccagcgga taaacaccgg tctgcggccc
    37561 gccgatcccg acagaacctg ccggaacgtg caagcgcggt tcagcgcgcc gtggcgtgtg
    37621 tagttgttcc ggcaaactcc cgagatacgg gaagcccggt tgaaaaccta aaaaccagac
    37681 cacgtattcc acggaggagt gcaattcaac aacctgtttt tcgctcaatc cacaatgcgc
    37741 cgcgaccacc gccaaatccg gtccggctgc gccaccgtaa actaccggaa tttcaataaa
    37801 gcgagactcc ggctccagcg cctcactctc ctcccaccag cgttgcaaac gctctatggc
    37861 atccagcgcc agcgactcag gattacgcaa aatcactgtg atattgttca tgccaggaat
    37921 ggcttcaacc acattcggca tatccaccag acgctgtgcc agtcgccaga tccgtttctg
    37981 gctagccagc gtcaccggcg gttccagttc cagtactacc gccgtttcac ctatcagata
    38041 acaacgcgct cgttgcactt tcgatccctc tgattattcg ttatgcagga ttaggaatat
    38101 caataaaggt cacatcaaga tcggtatttt cattcagcca ctcgctcaat gcgcgaatac
    38161 caccgcgttc agtggcatgg tgacccgcag cataaaaatg caatccctgc tcgcgggctg
    38221 aatgaatggt ctgttcagaa acttcgccag taataaaagc atccacgcca aaacgcgcgg
    38281 cgctatcgat aaaactttgc ccaccccccg tgcaccaggc gacgcgctgg accacctcag
    38341 gtccggtatc gccacaccat aacggcttac gtcccagacg cgcttcaatc caggaggcca
    38401 gttccagtcc cggcacaggc atggtcagtt cgccccacgg caccaacggc tcaatttcgc
    38461 ccatgaccgt gatccccagt aacgccgcca gctgtgcgtt attacccagc tccggatgcg
    38521 cgtccagggg cagatgccag ccatacaggt tgatatcatt cgccagcaac gtttttaaac
    38581 ggttacgctt cattccgcga atgaccggag attcaccttt ccagaagtag ccatgatgca
    38641 caatgaccgc atccgcgccc agacgcactg cctcatcgag caaagcctgg ctggcagtta
    38701 caccggtaac aattttttgc accatctctt tgccttccac ctgcaaacca ttcggcgcgt
    38761 aatcactaat cgccgcgctg ttcagttttt cgttaatcag ttgttccagt tcggtgtttt
    38821 tcatcttcgc gccttccgta ttctgatagc tacaccgtta acatagcgtt acctcgcctg
    38881 ttcgtcgata gccaatcttt tgacatatta agaaacaaac ccgacgccaa aagacgcaaa
    38941 ttgtttatat catcacgctt cagctaatgt atatttatgc aatcagacag catattgcat
    39001 aaataatcag atctgtatca aagttttaac tttaaggaaa cacaagcacg ccgcgcaact
    39061 attacgtgac gttgcagtca attgtggaat tattatgaat aaacacgcat cacaaccgcg
    39121 cgctatttac tatgtcgttg cgctgcaaat ctgggaatat tttagctttt acggcatgcg
    39181 tgccctgctg atcctctatc tcaccaatca actaaaatat agcgataatc acgcctacga
    39241 gttatttagc gcctactgtt cgctggtata tgtcacgcca atcctcggtg gctttttggc
    39301 ggataaagtt ctcggcaatc gcatggcggt gatgctgggg gcgttgttga tggcgatcgg
    39361 tcatgtggtg ctgggtgcca gtgagatcca tccgtcattc ctctatctgt ccctggcgat
    39421 tatcgtctgc ggctatggtc tgtttaaatc caacgtcagt tgcctgctcg gtgagctgta
    39481 tgagccaacc gatccacgtc gtgatggcgg tttctcgctg atgtatgcgg cgggtaacgt
    39541 ggggtctatt atcgcaccta tcgcctgtgg tttcgcccag gaagagtaca gttgggcgat
    39601 gggctttggc ctggcagcgg tgggtatgat cgcgggtctg gtcattttct tatgtggcaa
    39661 tcgtcatttc acacataccc gcggcgttaa caaaaaggta ctgcgtgcga caaactttct
    39721 cctgcccaac tggggatggc tactggttct gctggtggca acgcctgcgc tgattaccgt
    39781 gttgttctgg aaagagtggt cggtatacgc cttgattgtc gcgacgatca ttggccttgg
    39841 ggttctggca aaaatttatc gcaaagcaga aaaccaaaaa cagcgtaagg agctggggct
    39901 gattgttacc ctcaccttct tcagcatgtt gttctgggca ttcgcacaac aggggggtag
    39961 ctcgattagc ctttatatcg accgcttcgt taaccgcgat atgtttggtt ataccgttcc
    40021 gactgctatg ttccagtcga ttaatgcctt cgcagttatg ctgtgcggtg tgttcctggc
    40081 gtgggtggtt aaagaaagcg tcgcaggtaa tcgtaccgtg cgcatctggg gaaaatttgc
    40141 tcttggcctt ggcctgatga gcgccggatt ctgcattctg accttaagcg cccgctggtc
    40201 cgcaatgtat ggtcactctt ctctgccact gatggtgtta ggcctggcgg tgatgggctt
    40261 tgcggaactg tttatcgacc cggttgctat gtcgcagatt acgcgcattg aaatccccgg
    40321 cgtgaccggc gtattaaccg gcatttatat gctgctttcc ggcgcgattg cgaactatct
    40381 ggcgggcgtg attgccgatc agacatcgca ggcttcgttt gatgcttccg gggcgatcaa
    40441 ctactccatc aatgcatata ttgaagtatt tgatcaaatt acctggggcg cactggcgtg
    40501 tgtaggactg gtactgatga tttggctgta tcaggcgctt aagttcagaa accgcgcgct
    40561 ggcgctggag tcttaataag ccagcaccat gcctgataaa acgctcgctg cgttttatca
    40621 ggctcctttc ctcgcttctt cgtacgctgc cagcgttcgc agccttgcct ctttgtgatc
    40681 gactatcggt tgcggataat ccaacgtcac acctgttttc tctgcccact tccacggctc
    40741 atgcaccgct ttccccggta catcgcgcag ctccggtagc cactggcgga taaattcgcc
    40801 ttcgcggtca aatttctcgc cctgagttgt cgggttgaaa atacgaaaat acggcgctgc
    40861 atcagtaccc gtagaagcgg cccactgcca gccaccgtta ttagctgcca aatcaccatc
    40921 aatcagctgc gacatgaaat atcgctcgcc ttcgcgccag tcgatcaaca aatctttcac
    40981 cagaaaactg gctgtaatca tccgtagccg gttatgcatc cagccagtgc tgttaagctg
    41041 acgcatggca gcatcgacaa tcgggtatcc cgttttgcct tcctgccagg cctttaaatg
    41101 ggcgggatta ctttgccact gtacacgatc cgtccaggca ataaacggac gatgtttaca
    41161 cagcgaagga taatacgtca tcaaatggcg gtagaactcg cgccagatca gctcactaag
    41221 ccagacacta ccggctccac cgtccagcgc ctgcggctgt tccgccaaca agcgatgcaa
    41281 acactggcga ggcgataacc cgcccgttgc caggctggcg gacaaacgac tggtgccttc
    41341 tactgccgga aaatctcgtt gttgctcata ctctccggca ccgttctggc aaaactggcg
    41401 taattgcgca atcgccgctt tttcttccac cgggaaatgc gcagtatcga aagactgacg
    41461 aggataattc agcgtaatgg atggcgcggg atctatcgct ccactactac gtacttttgg
    41521 cgcagcgacg cactccggca tcccttcccg cagccgtttc agccaggcat tcttaaaagg
    41581 cgtaaagact ttgtacatct catgattgcc agtcatcacc gcccccggcg gcaggatcac
    41641 gctgtcatca aatccttcac acaccacgtt acgcagcgct ctttcaactt ccacatcccg
    41701 cgcccgctca tttacctcat actgatagtt ataaaaaaga tgagtaacgc ggttttccgc
    41761 gcacacctgt ttaactattt cgacgctggc ggcaaagtca tccacttcac ggaacaataa
    41821 aggaatacct ttttccgcca gcgcgttttg cagcgcatta agttgtgtat tgataagttc
    41881 agcctgacgc ggcgacacat tatgcgccgc ccactggcgt ggggtagcga tatacaacgc
    41941 cagcacgcgt gcagacgaat tgcggcaggc ggcagccagt gcgagattat cgtgcagacg
    42001 taaatcctgg cgaaaccaga ccagatgggt agtcataaaa ctcctgcatg gcgcaagtta
    42061 atcacacgcg gccaaagttc gaaataacgc tgccctgaaa gccaggcgtc aggataaagc
    42121 gccatatagt gtttgatacg catcagcggc gcaagaagcg attgctcgcc acggcgataa
    42181 ctgtcgataa gcgccgccag ctgctggcgt tctgtggaat caatatgtgg gcgaaaatat
    42241 ccctgaacgt gcatcaaaac gttagtatga tcacgccggt tggcagggtg agaaagcaaa
    42301 acaatcacgc gttggcggta ctggttgtaa tagtcatcca gactttgcca ccggtgaata
    42361 tcagccacaa acgggccaag tttgcggtac tccggctgag aatgcgccag aaagacgagt
    42421 ttatagcggc tgtgataatc gagaagcgcc ccgcgcgtta gtcctcgatc tttgagattg
    42481 tgtaactcat gcaaagcaaa aatgcggata agggtgctgt catcaaaaag ttgttgattc
    42541 attactgctc ctgaacggtt tacaggagta agtgtagacg ccgaaaaaag aaaaccgcca
    42601 gcgtttccac cggcggtttt ctttaaacgt catgtttggc aatcagtaaa aatcaccggt
    42661 tgccttttcg gcctgatcca tccacaccgg tttatcgctg gttttcgacc agacgcggtg
    42721 caggtagcta taaaagcggg cgcggtcttt ccagaaaagc atgaaaggca gcgccagaac
    42781 gcccgctgca accgcacaag tacggcgtaa aaagataagc catgcaggat attctttgta
    42841 gagttccata cttttctccc ccttttgtat ctacccggtg aatagcaccg gaaaaatgaa
    42901 ttcgtttatc tgatgaaaat agtaccgctg tttgtgtaat tttactactc atccgaccac
    42961 ttatttttgc ttattgatgg tttatttata ttcaccgtgt aattaagtta cataaaagtt
    43021 aaattaatac taaacattag ttaaatcatt gcttttgcca tttttatact ttttttacac
    43081 cacgcccgca gatttttgcg aaatctttgc agccagaact ctacccttcc ggtatcactt
    43141 ttaggccact ggaggtgcac tgtgagtgca ggcgtgataa ccggcgtgtt gctggtgttt
    43201 ttattactgg gttatctggt ttatgccctg atcaatgcgg aggcattctg atggctgcgc
    43261 aagggttctt actgattgcc acgtttttac tggtattaat ggtgctggcg cgtcccttag
    43321 gtagcgggct ggcgcggctg attaatgata ttcctcttcc tggtacgacg ggcgttgaac
    43381 gcgtactctt tagcgcgctt ggcgtctctg accgcgagat gaactggaag cagtatctct
    43441 cagccattct tggcctgaat atactggggc tggcggtgct gttttttatg ttgctcggtc
    43501 agcactatct gccgcttaat ccacagcagt tgccagggct gtcgtgggat ctggcgctca
    43561 ataccgccgt cagctttgtc accaatacca actggcaatc ttatagcggt gaaaccacgt
    43621 tgagctattt cagccagatg gcgggcttaa cggtacaaaa ctttctttct gccgccagcg
    43681 ggattgcggt gatttttgcc ctcattcgtg catttacccg ccagagcatg agcacactcg
    43741 ggaatgcctg ggtcgatctg ctacgcatca cgttatgggt gctagtccct gtggcgttgt
    43801 tgatcgcact gttttttatt caacaaggtg cgctgcaaaa ctttctgccc tatcaggcgg
    43861 tgaataccgt tgaaggagca caacagctgt tacccatggg gccagtagct tctcaggaag
    43921 cgatcaaaat gctcggaact aacggcggtg gcttttttaa tgccaactcg tcgcatccgt
    43981 ttgaaaaccc aaccgcactg accaacttcg tgcaaatgct ggcgattttc ttgatcccaa
    44041 cagcgctgtg ctttgccttt ggtgaagtgg cgggcgatcg tcgccagggg cgcatgttgc
    44101 tgtgggcgat gtcggtgatt tttgtcatct gcgtaggcgt agtgatgtgg gcagaagttc
    44161 agggtaatcc tcatctgctg gcgctcggcg cggacagcag catcaatatg gaaggtaaag
    44221 agagccgttt cggcgtgctg gtcagtagcc tgtttgcggt cgtgactacg gcggcttcct
    44281 gcggcgcggt gattgcgatg catgattcgt ttaccgctct tggtggcatg gtgccgatgt
    44341 ggttgatgca aattggtgaa gtggtattcg gcggcgtcgg ttccggcctt tacggcatga
    44401 tgctgtttgt cctgctggcg gtgtttattg ccgggctgat gattggtcgt acaccggaat
    44461 atctgggtaa aaaaatcgac gtacgcgaga tgaaactgac tgcactggcg attctggtca
    44521 ccccgacgct ggtgctgatg ggcgcggcgc tggcaatgat gaccgacgcc ggacgtagcg
    44581 ccatgctcaa ccctggcccg catggtttta gcgaagtgct gtacgccgtg tcatccgccg
    44641 ctaacaacaa cggcagcgcc tttgccggat taagcgccaa ctctccattc tggaactgtt
    44701 tactggcgtt gtgcatgttt gtcgggcgct tcggggtgat tatcccggtg atggcaattg
    44761 ccggttcgct ggtgagtaaa aagagccaac ccgccagctc cggcacattg ccaacgcacg
    44821 gcccgctgtt tgttggcctg ttaatcggca ccgtgttgct ggttggcgca ctgaccttta
    44881 tccctgccct ggcgcttggt ccggtggcgg aatatctctc ctgatgatat tgagtgagca
    44941 ctgaatatga gtcgtaaaca actggcgcta ttcgaaccaa cacttgtcgt tcaggcgctg
    45001 aaagaagcgg tgaaaaaatt aaacccgcag gcgcaatggc gcaatccggt gatgtttatc
    45061 gtctggatcg gcagtctgct gaccacctgt attagcatcg cgatggcaag cggtgtgatg
    45121 cctggtaatg cgctgtttag cgcggcaatt agcggctggc tgtgggtcac cgtactgttc
    45181 gctaatttcg ccgaggcgtt ggcagaaggc cgcagtaaag cgcaggccaa cagtctgaaa
    45241 ggggtgaaaa aaaccgcttt tgctcgcaag ctgcgcgaac cgaaatatgg cgctgtggca
    45301 gacaaagttc ctgccgatca actgcgtaaa ggcgatatcg tactggtaga agctggcgat
    45361 attatcccct gcgatggtga agtcattgaa ggcggcgcat cggtcgatga aagcgccatc
    45421 accggggaat cggctccggt gatccgtgaa tccggcggtg attttgcctc cgtcactggc
    45481 ggcacgcgta ttctttctga ctggctggtg attgagtgca gcgttaaccc cggcgagaca
    45541 tttctggatc ggatgatcgc gatggtggaa ggtgcgcagc gacgtaaaac gccgaacgag
    45601 attgccctga ccattctcct gattgccctg actatcgtct ttttactggc aaccgccacg
    45661 ctgtggccgt tttccgcgtg gggcggtaat gcagtcagcg taacggtact ggtggcactg
    45721 ctggtctgtc tgatcccaac cactattggc ggcctgttgt cagcgattgg cgtcgccggg
    45781 atgagtcgga tgctgggcgc gaatgttatt gccaccagcg ggcgtgcagt tgaagcggcg
    45841 ggcgacgtgg acgtcctgct gctggataaa accggcacca tcacactcgg taaccgtcag
    45901 gcgtcggagt ttatccctgc gcagggcgtg gatgaaaaaa cgctggctga cgccgcacaa
    45961 ctggcttcgc tggctgatga aacgccggaa ggccgcagta ttgtgatcct cgccaagcag
    46021 cgttttaacc tgcgcgagcg cgatgtgcag tcgctccatg ccacctttgt accgtttact
    46081 gcgcaaagcc ggatgagcgg gatcaacatc gacaaccgca tgatccgtaa aggttctgtc
    46141 gatgccattc gccgccatgt tgaggctaac ggcggtcact tccctgccga tgttgatcaa
    46201 aaagtcgatc aagttgcgcg tcagggagcc acgccgctgg tggtggtgga aggttctcgt
    46261 gtgctgggcg ttattgcgct gaaagatatc gtcaaaggcg gtattaaaga gcgcttcgcc
    46321 cagctgcgta aaatgggcat taaaacggtg atgattaccg gcgataaccg tctgactgcc
    46381 gccgcgattg ccgcggaagc gggcgtcgat gattttctcg ccgaagcaac accggaggcc
    46441 aagctggcgt tgattcgtca gtatcaggca gaaggccgtt tagtggcgat gaccggcgat
    46501 ggcaccaacg atgctccggc gctggcgcag gcggatgtcg cggtggcgat gaactccggc
    46561 acccaggcgg cgaaagaagc aggcaatatg gtggatctcg actccaaccc gaccaagttg
    46621 atcgaggtgg tgcacattgg caaacagatg ctgatgaccc gtggctcgtt gaccaccttc
    46681 agcattgcca acgatgtggc gaaatacttc gccattattc cagcggcgtt cgcggcaacg
    46741 tatccgcagt taaatgcgct gaacatcatg cgcctgcatt cgcccgactc cgccattctc
    46801 agtgcggtca ttttcaacgc cttgattatc gtctttttga ttcccctggc gttaaaaggc
    46861 gtgagttata aaccgcttac cgcttctgcc atgttgcgcc gtaacttatg gatttacggt
    46921 ctgggtgggc tgctggtgcc gtttattggt atcaaagtca ttgatttact gctaaccgtt
    46981 tgcggtctgg tgtgaggttt accatgagtg gattacgtcc ggcattatcg acatttctct
    47041 ttctgttatt gattactggc ggcgtttacc cgctgctgac caccgcactg gggcaatggt
    47101 ggtttccctg gcaggccaac ggttcattga ttcgtgaagg tgatacggtg cgcggttcgg
    47161 cattaatcgg gcaaaatttt accggcaacg gctattttca tggtcgcccg tcggcaacag
    47221 cagaaatgcc ctataatcca caggcttctg gcgggagcaa tctggcagtc agtaacccgg
    47281 tgctggataa acagatagcc gcacgcgttg ccgcattacg ggccgctaac ccggacgcca
    47341 gcacgagcgt tccggttgaa ctggtgacag cgtcagcaag cgggctggac aataatatta
    47401 ccccgcaagc ggcggcctgg cagatcccac gcgtggcgaa agcgcgtaat ctcagcgttg
    47461 aacagctcac gcaactgatc gcaaaataca gccaacaacc gctggtgaac tatatcggcc
    47521 agccggtcgt caacgttgta gaactcaatc tggcgctgga taagcttgat gaataacgaa
    47581 cccttacgtc ccgaccccga tcgtctgctg gaacaaactg ccgcgccgca tcgggggaag
    47641 ctgaaagttt tcttcggtgc ctgcgcaggc gtcggaaaga cctgggcgat gctggcagaa
    47701 gcccagcgac tgcgggcgca agggctggat attgtggttg gcgtggtaga aacccacggg
    47761 cggaaagata ccgccgcaat gctggaaggt ctggctgttc tgccgctgaa acgccaggcg
    47821 taccgtgggc ggcatatcag cgagtttgat ctcgatgccg ccctcgcccg ccgtccggca
    47881 ctgatcttaa tggacgaact ggcgcacagt aatgcgccag gttctcgtca tcctaaacgc
    47941 tggcaggaca tcgaagagct gctggaagca ggcattgatg ttttcactac cgtcaacgtt
    48001 cagcatctgg aaagcctgaa cgatgtggtc agtggcgtaa ccggaattca ggttcgggaa
    48061 accgtgcccg atcctttttt cgatgccgcc gacgacgtag tactggtgga cttgcccccg
    48121 gacgatctgc gccaacgact gaaagaaggc aaagtctata ttgccgggca ggcagaacgc
    48181 gccattgagc attttttccg caaaggcaat ctgatcgccc tgcgcgagct ggcgctacgc
    48241 cgtactgccg atcgcgtaga tgagcaaatg cgcgcgtggc gggggcatcc tggcgaagag
    48301 aaagtctggc acacgcgcga cgcgatcctt ttatgcatcg ggcataacac cggcagtgag
    48361 aaactggtcc gcgcggcggc gcggctggcg tcgcgcctgg gcagtgtctg gcacgcggtg
    48421 tatgttgaaa cccctgccct gcatcgctta ccggagaaaa aacgtcgggc aattctcagc
    48481 gccttacgtc tggcgcagga gttgggcgcg gagacggcaa cactttctga tccagcggaa
    48541 gaaaaagcag tagtgcgtta tgcccgtgaa cataatctcg gcaagattat tctcggtcgc
    48601 ccggcctcgc gccgctggtg gcgtcgggaa acgtttgctg accggctggc gcgcatcgcc
    48661 cccgatctcg atcaggtact ggtcgcgctt gatgaaccac ccgcccgcac gattaataac
    48721 gcgccggata gccgctcttt taaagacaag tggcgggtac agattcaggg atgcgtggtt
    48781 gccgccgcgt tatgcgccgt tatcacctta attgccatgc agtggctgat ggcgtttgat
    48841 gccgccaacc tggtgatgct gtatctgctt ggcgtggttg tggtggcact attttacgga
    48901 cgctggcctt cggtggttgc gaccgtcatt aatgtggtga gtttcgatct cttttttatc
    48961 gccccacgcg gcacgctcgc cgtctctgat gtgcaatatc tgctgacctt cgcggtgatg
    49021 ttaaccgtcg ggctggtgat cgggaacctt actgctggcg tgcgttatca ggcgcgggta
    49081 gcccgttacc gcgaacaacg cacacggcac ttatatgaaa tgtccaaagc tctggctgtg
    49141 ggccgtagtt cgcaggatat cgccgccacc agcgaacagt ttattgcctc cacgtttcat
    49201 gcccgtagcc aggtgttgct gcctgatgac aacggtaaat tgcagccttt aacacatccg
    49261 caaggaatga cgccgtggga cgatgccatc gcgcagtgga gttttgataa aggcctgcct
    49321 gcgggcgcgg gcaccgacac gttacccggt gtaccgtacc agattttgcc gctaaaaagc
    49381 ggcgagaaaa cctacggact ggtggtggtg gaaccgggga atctgcgcca gttgatgatc
    49441 ccggaacagc agcgcctgct ggagacgttt acgctgttag tcgccaatgc ccttgagcga
    49501 ctgacactga ccgccagcga agaacaggcg cggatggcaa gcgaacgtga acagatccgc
    49561 aacgccctgc tggcggcgct ttcgcatgat ttacgcacgc cgcttacggt gctgttcggt
    49621 caggcagaaa tcttaacgct cgatctggca agcgaaggat cgccccacgc ccgccaggcc
    49681 agcgagattc gtcagcatgt gctgaacacc acccgactgg tgaataatct actggatatg
    49741 gcgcgaattc agtccggcgg ctttaatttg aagaaagagt ggttaacgct ggaagaagtg
    49801 gtcggcagcg cgctgcaaat gctggaaccg ggtttatcgt cgcccatcaa tctttctctg
    49861 ccagagccgc tgaccttaat ccacgttgac gggccactct ttgaacgggt gctgattaac
    49921 ctgctggaga acgcggtgaa atatgcgggg gcgcaggccg aaattggtat caatgcccac
    49981 atcgagggcg aaaatctaca actggatgtc tgggataacg gccccggtct tccaccaggc
    50041 caggagcaga cgatatttga taagtttgct cgcgggaata aagagtcggc ggtaccgggt
    50101 gtagggcttg ggttggcaat ttgtcgggcg atagtggatg tacacggcgg caccattacc
    50161 gcattcaacc gaccggaagg tggtgcctgt tttcgtgtta cacttcccca gcaaacagcc
    50221 cctgaacttg aagaatttca tgaggatatg tgacaaacgt tctgattgtt gaagatgaac
    50281 aggctattcg tcgctttctg cgcacggcgc tggagggcga tgggatgcgc gtctttgagg
    50341 ccgaaacgct gcaacgcggc ttgctggaag cggctacccg taagccagat ttgattattc
    50401 tcgatctcgg cctgcccgat ggtgatggga ttgagtttat ccgcgacctg cgccagtgga
    50461 gcgcggtgcc ggtgattgtg ctttccgcac gtagcgaaga gagcgacaaa atcgccgcgc
    50521 tggatgccgg agcggatgat tatctgagta agccgtttgg cattggcgaa ttgcaggccc
    50581 gtctgcgcgt cgctttacgt cgccactccg ccaccgccgc gcccgatccg ctggtgaaat
    50641 tttccgatgt taccgtcgat ttagccgccc gcgttatcca tcggggcgag gaagaggtgc
    50701 atctcacccc gattgagttc cgcctgctgg cagtgttgct caacaacgcc ggaaaagtgc
    50761 tcacccagcg ccagttactc aatcaggtgt ggggaccaaa cgcggtcgaa cacagccact
    50821 atttgcgtat ttatatgggg catctgcgac aaaaactgga gcaagatccc gcccgccccc
    50881 gccattttat tactgaaacc ggtattgggt atcggtttat gccatgaatt attattcaat
    50941 aaatacgctt aaataattat taatttatta ttaaacctgc cccgaaaatt attatttggc
    51001 aggtttaatt tcttaatgaa aatacaaccc acaaaattgc aacatttaaa caacaaaaca
    51061 gcatctaata tggcgctatt catcattaat gatttattat ttgggatatg atcgtttttt
    51121 gttgatcttc ttcacagatt atagccattt catggataga ataaccctac cttcaactga
    51181 cacagaaaaa ggtaaaggta aatggaaaat aataaccgct taatgcctca tataaggcgg
    51241 acaacccata tcatgaagtt tgcccatcgt aatagttttg actttcattt ctttaatgcc
    51301 cgctagtctt ctgactaaag ggcaccccag cgtacaggtc tccctgactt taagcattac
    51361 aggttaatac ctgtatccct cggtgctcat atactgctaa cccttttaaa ctctaaataa
    51421 ttcgagtcgc agcacatgca acttgaagta tgacgagtat agccagttac cgggctggtc
    51481 tgggttattg catctgcaaa aagcaaacta ctgatttatt tatcagcggt ggggttttgc
    51541 ttttttccgg cgtgatcaat ttctcctttg agaaattgag gacctgctat tacctgaaat
    51601 aaagagatga acaaaatgtc agaattaaaa attgccgtta gccgttcttg cccggattgt
    51661 ttttccactc atcgtgaatg cgtgaatatt gacaaaagta attatattga cgttgccgcc
    51721 attattttat cagtcaatga tgttgaacat ggaaaactcg atgaaataga cgctactggc
    51781 tatggcattc ctgtttttat tgcaacggaa aatgaagaac gtgtaccagc agaatatctg
    51841 ccacgtattt ctggtgtctt cgagcattgc gaatcacgga aagagtttta tggacgtcag
    51901 ttagaaaccg ctgccagcca ttatgaaacg caactgcgcc cgcccttctt ccgcgcactg
    51961 gtcgattatg tcaatcaggg caatagcgct tttgactgcc cgggtcatca gggaggtgag
    52021 tttttccgtc gccatccggc aggcaatcag ttcgtggaat attttggcga aatgctcttc
    52081 cgctccgact tgtgtaatgc cgacgttgca atgggcgatc tactgattca tgaaggtgcg
    52141 ccatgcattg cacagcaaca tgcggctaaa gtgtttaatg ccgataaaac gtactttgtt
    52201 ttaaacggca catcctcctc caacaaagtg gttttaaacg ccctgctgac accgggtgat
    52261 ctggtgctgt ttgaccgtaa taaccataag tctaaccacc acggagcgtt gctacaggct
    52321 ggtgcaacac cggtttatct ggaaacagca cgtaacccgt atggttttat cggtggcatt
    52381 gatgcgcact gcttcgaaga aagttatctg cgtgaactga ttacagaagt tgcaccgcaa
    52441 cgggcaaaag aggcgcgtcc gttccgcctc gctgtgattc agttaggcac ctacgacggt
    52501 actatttata acgcccgcca ggtggtggat aaaatcggcc atctgtgtga ctacatcctg
    52561 tttgactccg catgggtcgg ctatgaacag tttattccga tgatggcgga ctgttcgccg
    52621 ctgctactgg agcttaatga gaacgatccg ggtattctgg ttacgcaatc tgtgcataaa
    52681 caacaggctg gtttttctca gacttcacaa attcataaaa aagacagcca tatcaaaggg
    52741 caacagcgtt atgtaccgca caaacgcatg aacaacgcct ttatgatgca cgcctccacc
    52801 agcccgttct atccgctgtt tgccgcactg gatatcaacg ccaaaatgca tgaaggtgtc
    52861 agcggtcgta atatgtggat ggattgtgtg gttaacggta ttaatgcccg caaattgatc
    52921 ctcgataact gccagcacat tcgcccgttc gttcctgaac tggtggatgg taaaccctgg
    52981 cagtcgtatg aaacagcgca aattgcggtt gatctgcgct tctttaaatt tgtacccggt
    53041 gagcactggc attcttttga aggctacgca gagaaccaat actttgtcga tccgtgcaaa
    53101 ctgttgctga caactccagg tattgatgca cgtaacggcg aatatgaagc gttcggtgta
    53161 cccgcaacga ttcttgctaa cttcctgcgc gaaaatggcg tagtgccgga aaaatgcgat
    53221 cttaactcca tcctcttcct gctgactccg gcagaagata tggccaaact gcagcaactt
    53281 gttgccctgc tggtacgctt cgaaaaacta ctggaagctg atgcgcctct ggcggaagta
    53341 ctgccttcca tctacaaaca gcatgaagag cgctacgccg gttataccct gcgtcagttg
    53401 tgccaggaaa tgcatgattt gtatgcccgt cacaacgtga aacaactgca aaaagagatg
    53461 ttccgtaagg aacacttccc tcgcgtcagc atgaatccgc aagaagccaa ctacgcctac
    53521 ttacgcggtg aagtggagct ggttcgtctg ccggatgcag aaggccgtat cgctgccgaa
    53581 ggtgcgcttc cttatcctcc gggtgtgctg tgtgttgttc ctggtgaaat ctggggtggt
    53641 gctgttctgc gttacttcag cgctctggaa gaaggcatca acctgctgcc aggttttgca
    53701 ccggagctgc agggtgtcta tatcgaagaa catgatggtc gtaagcaagt ttggtgctat
    53761 gtcatcaagc ctcgtgatgc gcaaagcgcc ctgttgaaag gggaaaaatt atgagtcagg
    53821 cgaaatcgaa caaaatgggt gtcgttcagt taaccatact gacgatggtc aacatgatgg
    53881 gctccggtat catcatgctg ccgacaaagc ttgccgaagt cgggacaatc tcaattatct
    53941 cctggctggt gacagccgta ggctcaatgg cactggcatg ggcattcgca aaatgcggta
    54001 tgttcagccg taaatcagga ggtatgggcg gttatgccga gtatgctttc ggtaaatccg
    54061 gtaactttat ggcgaactat acctacggcg tctcgctgct gattgctaac gtcgcgattg
    54121 ctatttcggc ggttggttac ggcaccgaac tgctcggcgc gagtttgtcg ccagtgcaga
    54181 ttggtcttgc gaccatcggg gtgctgtgga tttgtaccgt ggctaacttt ggtggtgcgc
    54241 gcattaccgg gcaaatcagt agcattaccg tgtggggggt cattattccg gtggtaggcc
    54301 tgtgcattat cggctggttc tggtttagcc cgacgcttta cgttgattcc tggaatccgc
    54361 atcatgcacc cttcttcagt gcggtaggtt cttccatcgc tatgacgctg tgggcttttc
    54421 ttggtctgga gtctgcgtgt gcgaatactg atgtagtgga aaacccggaa cgtaatgtgc
    54481 caatcgcggt actcggcggt acgttaggtg cggcggtgat ttatatcgtc tccaccaacg
    54541 tgattgccgg gattgtgcca aatatggagc tggcaaattc aacggcacca tttggtctgg
    54601 ccttcgcgca gatgttcacg ccggaagtgg gtaaagtcat tatggcgctg atggtgatgt
    54661 cctgctgcgg ttcgctgctt ggctggcagt tcaccattgc ccaggtgttt aaatcttcat
    54721 ctgatgaagg ctacttccct aaaattttct cccgtgtaac caaagtggat gcaccggtgc
    54781 agggaatgtt gaccattgtg attatccaga gcgggttggc gctgatgacg attagcccgt
    54841 cgctaaacag tcagttcaac gtgctggtta acctggccgt ggtgactaat atcattccgt
    54901 atattctgtc aatggcggca ttagtcatta ttcagaaggt cgctaatgtg cccccctcaa
    54961 aagcgaaagt tgcaaacttt gttgcttttg ttggcgcgat gtacagcttt tatgcgctgt
    55021 actcatccgg ggaagaagcc atgctatacg gttccatcgt gaccttcctc ggttggacac
    55081 tgtatggtct ggtctcacca cgctttgaac tgaaaaataa acacggttaa ttaagcaaag
    55141 caaaaaaggg cgatcttccg accgcccttt ttcttatttg atatgtttac gcgtttttca
    55201 gaacttcgct aacaatttca accgcttctt tctcaatctg cttgcgatgt tcttcaccaa
    55261 ggaagctttc gcagtagatc ttatatgcgt cttccgtgcc tgacggacgc gcggcgaacc
    55321 agccgttgtc agtcatcact ttcagaccgc cgatagaagc gccattaccc ggtgccgccg
    55381 tcagacgcgc ggtgatcggg tcacctgcca gggtgctggc gctcaccatt tccggagaca
    55441 gcttagacaa cgccgctttt tgtgcggaag tcgctgctgc ctgcaaacgg ttatagctcg
    55501 gcgcaccaaa gcgttttgcc agttcgttat agtgttcctg cgggttctta ccggtgacag
    55561 cggtgatttc cgccgccagc agacacataa tgatgccgtc tttatcggtg gaccacggcg
    55621 tgccgtcgaa acgcaggaag gaagcccctg cgctctcttc gccgccaaag ccgaagctgc
    55681 cgtcgaacag accatcaaca aaccatttga aacctaccgg gacttctacc agcttacggc
    55741 ccaagtcatt gaccacacgg tcgatcatcg cagatgaaac cagcgtttta ccgacagcaa
    55801 catctttgcc ccactgcgga cgatgctgga acaggtaatt gatcgccacc gccaggtagt
    55861 ggttcggatt catcaaacct gccggagtga cgataccgtg acggtcataa tccgggtcgt
    55921 tagcaaacgc cagatcgaac ttatcacgca gtgccagcag gcccgccatc gcacactcgg
    55981 aggagcagtc catacggatc gcgccgtctt tatcaaggtg cataaagcgg aaggtttgat
    56041 cgacctgatc gttaacaata gtcaggttga ggttgtaata ctcgccaata cgcttccagt
    56101 attcgatacc ggaaccgccc agcggatcaa cgccaagcgt caggcccgct ttctgaatcg
    56161 ccgccatatc aacgatatcg gccagccctt ccacaaacgg ctgcaccaga tcctgctctt
    56221 tcacatgacc ggatgccatc gcttcgtcga gggagatacg cttcacgcct ttcaggccat
    56281 cagccagcag tgcgtttgct ctgtcttcca ccactttagt gacgttggta tcagccgggc
    56341 caccatttgg cggattgtac ttgataccac catcttccgg cgggttatgg gacggtgtaa
    56401 tcacgatacc gtctgccagc gggccacctt ttttattgtg aaccagaatg gcattggaaa
    56461 tggcaggtgt cggagtgaag ccattgtttt cctgcacaat gacatcaacg ccgttcgctg
    56521 ccagcacttc cagtacggaa atgaacgcag gctcggacag ggcgtgagta tctttaccca
    56581 catagcaagg gccagtgatg ccgtttttcg cacgttcttc agcaattgcc tgagcgatcg
    56641 ccagaatgtg cggctcgtta aagctgtggc gcgctgcact gccacggtga ccggaagtac
    56701 cgaatttcac cgcgtgctcc gcattccctg cttctggttt cagtacataa tattgcgccg
    56761 tcagttgggc gacgttaatc aaatcactct gttgtgcagg ttggcctgca cgattgtgga
    56821 ttgccattgc tttgtccttt gtctgcaacg ttttagatag ttccgcaaac cttctcaatc
    56881 aattccgccg ggaattgcat cgactgcatg atgtgttcga tcatgctgca tttacggccg
    56941 gtgttggtgt tggtgatcac ccaatacggc gtaccaggca catgtttcgg cttggtctga
    57001 ttaccatttt tcagcagcgt ttgttcatct gccgcaaagt aaacgcgtgt acgaccgtgc
    57061 aacgattccg ttgcttcggc aaacgcctgg gcgtcaagag aatatagtgt agacaacagc
    57121 agcataaagc gattgaccgc tcgcttttgc tctgcgtatt cgtccgaaag cagaagttca
    57181 cgcattgcgc gaaccttgtc tttaatcgtt ttgaccggct tcgcttcgac gatagcaggt
    57241 gacgcaacgc gaacctcttt cgtcaccgga gcagcaggct gtgatgcggc ggtaaatttc
    57301 aacatacgcc gtaaaatgtc ggatgcgctc tcgccgatat gcttagtgtg gctggcaata
    57361 tagctgtaga gttcatcatc aacttcaatc gttttcatct taatccagtg cagtgtctta
    57421 gctgaataca agtcgccagg agtatatgaa taaatcccgg cagcggatag cgtcaagcct
    57481 ggcttgcaga aaaactcgga ataaacctta tttgttgcag ccctgtggca caatggtcaa
    57541 cataataccc taacccgaca acgcgaaaaa aagaactttg ccatgaaatt gaatatccgc
    57601 gcgcaaactg cacaaaacca gcacaataat tctcccatcg ttcttgtcca tggtctgttt
    57661 ggcagcctcg acaaccttgg cgtactggct cgcgatctgg taaacgatca caatatcatc
    57721 caggttgata tgcgtaacca cggtctttca ccgagagatc cggtaatgaa ttacccggcg
    57781 atggcgcagg atcttgttga taccctggat gcacagcaga tcgacaaagc aacatttatc
    57841 ggtcactcca tgggcggtaa agcggtaatg gctcttactg cactagcccc tgatcgcatt
    57901 gacaagctgg tggcgattga tattgcgccg gtcgattatc acgttcgccg tcatgatgag
    57961 attttcgcgg ccatcaacgc agtcagtgaa tcagacgcac aaacacgcca gcaagcagcg
    58021 gcaataatgc gccagcatct taatgaagaa ggggtgattc agtttctgtt gaaatctttt
    58081 gttgacgggg agtggcgctt taacgtgcca gtattgtggg atcagtatcc gcatattgtg
    58141 ggttgggaga aaatcccggc atgggatcat cctaccctgt ttatccctgg cggcaattct
    58201 ccgtatgtta gcgagcagta ccgtgatgat ttactggcac aatttccaca ggctcgggcg
    58261 catgtgattg caggcgcggg tcactgggtc catgctgaaa aaccggatgc ggtattacgc
    58321 gctatccgtc gctatctcaa tgattaacgc aactgattaa aaacccagcg tccgcgtcgc
    58381 tttccgcgcg tggacgttgg cgtgactcat cgcgctgatg tattatggcg cgctatccat
    58441 ccgggcagag gcctggctga ttgtttcccc cgaagtcacc aagatcatgg ccaaagaaca
    58501 aacggaccgt acgacattag atctgttcgc gcacgagcgt cgaccgggac gaccgaaaac
    58561 taatccgctt tcgcgcgatg aacagctgcg tattaataaa cgcaaccaac taaaacgcga
    58621 caaagtacgt ggccttaagc gtgtcgaact gaagctgaac gcggaagctg tcgaggcgct
    58681 gaacgagctg gcggaatcgc gtaatatgag ccgtagcgaa ctgatcgaag agatgttaat
    58741 gcagcaactg gcggcgctgc gtagtcaggg catcgtttaa atttccactt tcatgtagca
    58801 cagtgtgcag tcctgctcgt ttgctgattc cgcaagactg cctgttctgc tatgattgcc
    58861 tttatccgtg ggcaattttc cacccccatt tcaataagtt tcaagaggtt atttcactca
    58921 tggctatcac tggcatcttt ttcggcagcg acaccggtaa taccgaaaat atcgcaaaaa
    58981 tgattcaaaa acagcttggt aaagacgttg ccgatgtcca tgacattgca aaaagcagca
    59041 aagaagatct ggaagcatat gacattctgc tgctgggcat cccaacctgg tattacggcg
    59101 aagcgcagtg tgactgggat gacttcttcc cgactctcga agagattgat tttaatggta
    59161 aactggttgc gctgtttggt tgtggcgacc aggaagatta cgcagaatac ttctgcgatg
    59221 cattgggcac catccgcgac atcattgaac cgcgcggcgc aactatcgtt ggtcactggc
    59281 caaccgcggg ctaccacttc gaagcgtcaa aaggtctggc tgatgatgac cactttgtcg
    59341 gtctggctat cgacgaagat cgtcagccgg aactgaccgc tgaacgtgta gaaaaatggg
    59401 ttaaacaaat ttctgaagag ctgcatctcg acgaaattct caatgcctga tgtgatgcgg
    59461 cgtagactca tgtctacgcc gtattaatag ataatgccaa tcaaaataat tgctacaaat
    59521 ttgtaacttt tgctgttgta cctgtacaat gtcccggtgt tcaagtggcc ttgccgttgt
    59581 aaatgtaagc tgtgccacgt ttttattaac aatatttgcc agggacttgt agttttcatt
    59641 taggcgtggc aattctataa tgatacgcat tatctcaaga gcaaattctg tcacttcttc
    59701 taatgaagtg aaccgcttag taacaggaca gattccgcat gactgataac aataccgccc
    59761 taaagaaagc tggcctgaaa gtaacgcttc ctcgtttaaa aatcctggaa gttcttcagg
    59821 agccggacaa ccatcacgtc agtgcggaag atttatacaa acgtctgatc gatatgggtg
    59881 aagaaattgg tctggctacg gtatatcgcg tactgaacca gtttgacgac gctggtatcg
    59941 tcacccgcca caattttgaa ggcggtaaat ccgtatttga actgacacag caacatcacc
    60001 acgatcacct gatctgcctc gactgcggta aggttatcga atttagtgat gattccatcg
    60061 aagcgcgtca gcgtgaaatc gccgcaaaac atggcattcg cctgactaac cacagtctct
    60121 atctttacgg tcactgtgcc gaaggcgatt gccgcgaaga tgagcacgcg cacgaaggca
    60181 aataagccag cctgaacgag aaaagccaac ctgcaggttg gcttttttat acaagggaaa
    60241 taagaaaagc gagagttaca gctctcactt atttgttatt actgcgaatt tcctgccaga
    60301 ccttatcaca atcggctttc accgcctgat catttccggt ttgcgttgcc tgaatgcact
    60361 gctgataatc cagtacgcgg acactttcct gctcggcaaa ctgctgatgt tgtttctctt
    60421 tcttcagcac gtttaacacg ctctggcagg cttcaatttt ttccggcgaa ccttgcgcgg
    60481 tgttgataca ggcgctgtaa gcctctttca gacgactgtc ttcctgtggc gcggttgatt
    60541 gcgcacaagc caccagcccc gatgccatca tggcgatgag aatcagtttt ttcatagcaa
    60601 attcctcaaa cgtgcggcag gcacaaaacc tgccgcatcg ggcatcagaa gatggtgaat
    60661 ggtgcgatta ccataaattt cacgtcacgc tcatcctgga agatgttgcc ataaccaccg
    60721 ccccagcttg ggatgtcgga gtggttgtcg tattcggtga agtgcagttt gaacatcgtg
    60781 cctttggcgc ggccgtcctg aatggtgtag accgcatcca ggctgtaggc agactcttca
    60841 atagtccggt ttttgtcgta gtacgcatcc ggattgctct gccaggtagc gggtttagca
    60901 tcccatgcgt aaacgtagga ggcgccgatg gcaaaacctg gaagattcca gtttttcagg
    60961 tcatacatcg cgccgaagaa gaccgctttt tcgccgttgg cgttgaagtc agaacggtta
    61021 tcccaccaga tatccaggcg accgttcgag gaagcgtagg ttggtgtcat acgttgcagg
    61081 aagtatccct gctgaccgtc ggctttaacc caggtgcctt ccagacgcaa atccactacg
    61141 tcagccgccc ggtaaccaaa ggtcaacgcc tgcagccagg cggtgccgtc ataaagatcg
    61201 ttggcgctgc gatcgtcaac tttatcgcgc gtgccataga actggtagct ggtggttaac
    61261 gggctaccgg cgatatcaaa tttgtagctg gctttggcaa aatattgatc gatataccct
    61321 tcggcctgac caaacgccgc ttccagtacg aagttatttt tgaagtcgta cttcgcccca
    61381 agggagtgta gataatcaac tttggtggtt ttatcgttct gataaaactc atccatttcc
    61441 agatgccacg gtgctttgta ttcgttggtc cacatgtagg agaaactcaa cgcaccagca
    61501 tcgccgtaat caaaattcgc cccggcctcc gccccctgat aagtacccgg cataaagctc
    61561 cagtgtggcg ctaacagcgt ctgaccggtt ggctgaatat aacctgccct cgcccaaacc
    61621 ggaccgtatt taaatttggc cgctgcttta tacaggctta taccgctttt atcgccggac
    61681 cagtcttcgt cataggcttt attacttttt gaaaacgcga tttcgttcgg gtgagagctg
    61741 tcgccgtttt ccgccatttc aatcgccgta aacgcggcaa tatcaaggcc gaacatatca
    61801 gcagcataac cagactgaaa atcgaggttg gcgttccagg tggagtgaga aaggttggtt
    61861 ttgtatttat cgccgtcggt aacatcttta cggtcgcgtt cacgctgcca gtaatagata
    61921 ccgccggtta aggttgaatc gtcgatgaat ccttcggcgc gagcctccgg aattgccata
    61981 aagcccgaca tagctgtaac accggcgata gccagcgcca gcgtactacg tttgccacta
    62041 aacgcacgca tgggttaatc ctctttgacg tataaattgc tgcaccaaag gtgaacagcg
    62101 aaaaaaataa aaatta
//
LOCUS       DAPOXO010000018        61284 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPOXO010000018 DAPOXO010000000
VERSION     DAPOXO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 61284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61284
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.018"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(18..299)
                     /locus_tag="ROH59_001440"
     CDS             complement(18..299)
                     /locus_tag="ROH59_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HDX4803948.1"
                     /translation="MNKYWLSGIIFLAYGLASPAFSSETATLTINGRISPPTCSMAMV
                     NGQPQQHCGQLTYNVDTRHQVSSPVKGVTTEVIAADSDSKRRIVLNRYD"
     gene            complement(562..1671)
                     /gene="apbC"
                     /locus_tag="ROH59_001441"
     CDS             complement(562..1671)
                     /gene="apbC"
                     /locus_tag="ROH59_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HDX4803949.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            1803..3836
                     /gene="metG"
                     /locus_tag="ROH59_001442"
     CDS             1803..3836
                     /gene="metG"
                     /locus_tag="ROH59_001442"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDX4803950.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAIREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            3977..7777
                     /locus_tag="ROH59_001443"
     CDS             3977..7777
                     /locus_tag="ROH59_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HDX4803951.1"
                     /translation="MRHFIYQDEKSHKFWAVEQQGNELHVSWGKVGTNGQNQVKSFAD
                     AAAAEKAKLKLIAEKTKKGYVENASANVHITPITKATPEVETSPESKNQRPWLADDAV
                     IRLTDDINRFAFPHRSRPREINYLHKDSQIWQRIANNTRAYDPANNYRSYPENWQQAF
                     AELQRRILDNQQTGSAQSDAALLWSFWNSYSADELVDDLIIRCGMESAVEIALLALQL
                     RYKPVKGAVTTIIPPNHEAESLPSWHQRLCHHLSLASEDEWQRCVDKVLAAITTLSPA
                     RQPFAALLLPERPDIANAMALRYADQNVPAMTWLRLVVTDEAALTAAEKYDFPPLYRD
                     FRAYLAMLLANNGVSGVSRILTEFVEEHSDNPTYLFERISETEDLVKWLWKTNHPDAI
                     QILILGVIGKKKHLEYLSKACQKHPAAAIAAYATLLAIHEDKEWHKALVKLITITPEL
                     VCDVIPWVSAKAAGILSECRPQSVAEECEYATADMLPELFVSPPWMTKEKKKNSPVFD
                     LPVLPVPSVSDVTPEIAKKLTRTYLVTRFQQIAQQQATKQILFTDLPLMEKASWERHL
                     VPLTPEQQILWCLGFDKWRESGEKIYEKIPAPQSAVDALLRFDFPALNAEFAQYHNNA
                     YKSWNLIALCYLPGQQAISFLNQIVKEDNYSGEGYILAIFGSAAIPAFMTCLQREPQR
                     LWFFTFFLGVNELALPMAQRLQKKMSYEDARNWLTDYPRHAAAGLLPVALGKQGKDRD
                     CARQALRLLVNLNQRETIEEIAQGYNQPDVLAALATLFDSEPLEEYPAKIAPLPGFYQ
                     FTLWRRPRLKSNNQPLPDDAMRHLGIMLSFPRDITPYAGLAIIKETFTRESLAEFGWD
                     LYTAWTEAGAPAKENWAFTSLGILGNDDTARKLTPLIRTWPGESQHKRAVYGLDVLAS
                     IGSDIALMLLNGIAKKIKFVALQEHACDKINMVAENRGLTMAELEDRLAPDLGLDSSG
                     SLTLDFGPRQFTVGFDETLKPVVRDANGKVLKDLPKPNQSDDKTLATDAVNLFKQLKK
                     DVRAIASQQIDRLEQAMCQRRRWTAEQFRLFLVEHPLVRHLTRRLLWGVYTEENTLIA
                     CFRVAEDSTYSDAQDELFTLPAGNIGIPHVLEISPESAAAFGQIYTDYEQLPPFRQLD
                     RGYYHLADNERDSHELIRWQGRLCQAGRIVGLERRGWQRLEESGSVYAMRKSTPYGDL
                     ELETEPFSLIYGETGYGDQLPVESVKITSPDNRYGKQSSLTFSALDDITASELINDIE
                     SLFD"
     gene            7790..11551
                     /locus_tag="ROH59_001444"
     CDS             7790..11551
                     /locus_tag="ROH59_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000860751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HDX4803952.1"
                     /translation="MKTYIYQDEKSHKFWAVEQQENELHISWGKVGTNGQSQIKSFAD
                     AAAAEKAELKLIAEKTKKGYAEEVSVTTPTSAPVQVIACSEKAPLPQDKPPFAEDHLP
                     WLADDAQIILPTEVAPTTLSHRRWPGDSVPQENELTLLRSVAAHTHRRFKKVITFDYS
                     TCSLDWQQAITQAVGLIDSPISTALPPMVLAVLVALEQGFNRNDHEELMDQIVQEGGL
                     EYATEVVIALQAIRFDWNYDAHLITFTPDNKQPGYLSRFASVEMRLRKHLSLANDDVW
                     QRCADKLIAALGNIPAWHQPLVALLLPEKQDVSHEIARRLCGQKGLYALEWLKLTAAD
                     EQVLAELGKYYPGQPGQVFDDYYGGKIWCATILKEQGVGALARFAPYAAGDTCGEVLM
                     HINHPQALTLLIHASEQGKRCHDRMTKTFVRFPHAALAALAELLAQKDQKRWRMMLMT
                     MLISQPTLAERVIPWLSTPAVAVLKSCQQQLTQPSNHASADMLPAVLVSPPWLSKKKK
                     SVMPVLDLTPLPLESCCTLTETAEKEIHARHRWHAHQIDIGQKEDIQNYLTRLGFNRW
                     NNGQYMKASDAVVELWQRGDYSALISEFKTFWHSYQREWQLYMLAALPIEKTAQAWNV
                     LSKEPHVGVEFVMTHLQLAGLQGFIHSFSRYPQEALPVAQYFAAIELAPLIARAFNKL
                     KTLRQDARIWLLKYPEHAITGLLPAALGKTGEAQDNARAALRMLTENGHQPLLQEIAR
                     RYNQPEVTDAVNALLALDPLDNHPTKIPTLPTFYQPSLWTRPLLKANAQSLPDSALLH
                     LGEMLRFPQEEALYPGLLQVKDACTTDSLAEFAWDLFTAWQTAGAPSKESWAFTALGV
                     LGNDDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNGIAQKLKFKALQ
                     ERAKEKIANIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFTVSFDETLKPFV
                     RDASGSRLKDLPKPNKSDDESQANNAVNRYKLLKKDARTVAAQQVARLESAMCLRRRW
                     SPENFQLFLVEHPLVRHLTRRLIWGVYSAENQLLACFRVAEDNSYSTADDDLFTLPEG
                     DISIGIPHVLEISPTDAAAFGQLFADYELLPPFRQLDRNSYALTEAERNASELTRWAG
                     RKCPSGRVMGLANKGWMRGEPQDGGWIGWMIKPLGRWSLIMEIDEGFAVGMSPAELSA
                     EQLLSKLWLWEGKAESYGWGSNSTQEAQFSVLDAITASELINDIEALFE"
     gene            11561..15193
                     /locus_tag="ROH59_001445"
     CDS             11561..15193
                     /locus_tag="ROH59_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDX4803953.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRNWPGEPVPVITENIIQ
                     TLGDELLQKAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSITARTMAALACIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFIVRCYESDPLVVTLQYQNEDYGYGYRSETY
                     NEFDLRLRKHLSLAEESCWQRCADKLIAALPGITKVRRPFIALNLPEKPEIANELVSL
                     ECSQTHFRSKEWLKVVADDPKAVKELARYWSQDIFSDREASYMSHENHFGYAACAALL
                     REQGLAAVPRLAMYAHKEDCGSLLVQINHPQVIRTLLLVADKNKPSLQRVAKYSKNFP
                     HATLAALAELLALKAPPARPGYPIIEDKKLPAQQKARDEYWHTLLQTLMASQPQLAEE
                     VMPCLCTQAQAVVNGYLSASPKLAFESTHSNDLPEILVSPPWRGKKKTALLRLDLVPL
                     ELAPKARWQPGERERLAATESARYFSTGSFTERMERKSGRVVLQELGFGDDVWLFRNY
                     ILPGKLDAARKSLVGQWHYSPRRVEEINNGWHSTEAKSAEQALRSGDVEALINTWEND
                     SYSHYRQEKSVWNLYLLAQLPREMALTFWLRINEKKHLFAGEDYFLSILGLDTLPGLL
                     LAFSHHPKETFPLILNFGATELALPVARVWRRFAAQRDLARQWILQWPEHTATALIPL
                     VFTKPSDNSEAALLALRLLYEQGHGELLQTVANRWQRTDVWPALEQLLKLGPIEIYPA
                     RIPKAPDFWHPGMWSRPRLITNNQPVTDDALEIIGEMLRFTQGGRFYGGLEQLKTFCQ
                     PQTLAAFAWDLFTAWQQAGAPAKDNWAFLALSLFGDETTARDLTTQILAWPQEGKSAR
                     AVSGLNILTLMNNDMALIQLHHISQRAKSRSLRDNAAEFLQVVAENRGLSQEELADRL
                     VPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRLRADDDQLKAPE
                     ALARLKGLKKDATQVSKNLLPRLEAALRITRRWSLADFHSLFVNHPFTRLVTQRLIWG
                     VYPANEPRRLLNAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMAAEMRSEFAQLF
                     ADYEIMPPFRQLARRTVLLTPDESASNSLTRWEGKSATVGQLMGMRYKGWESGYEDAF
                     VYDLGAYRLVLKFSPGFNHYNVDSKALMSFRSLRVYRDNKSVTFAELDVFDLSEALSA
                     PDVIFH"
     gene            15254..15570
                     /locus_tag="ROH59_001446"
                     /pseudo
     CDS             15254..15570
                     /locus_tag="ROH59_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16272..17360
                     /locus_tag="ROH59_001447"
     CDS             16272..17360
                     /locus_tag="ROH59_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416623.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDX4803954.1"
                     /translation="MSPQNNHLQRPPAAVLYAVELAKLKQNDNAPCPPGWQLSLPAAR
                     AFILGDEAQNIRRKVVISPSAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYLGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCIAGTIVKDNEEDRAR
                     LRRYFEQRVATHKEAHWQAYYQARHRLP"
     gene            17371..19650
                     /locus_tag="ROH59_001448"
     CDS             17371..19650
                     /locus_tag="ROH59_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4803955.1"
                     /translation="MSEPLIVGIRHHSPACARLVKSLIESQRPRYVLIEGPADFNDRV
                     DELFLAHQLPVAIYSYCQYQDGAAPGRGAWTPFAEFSPEWQALQAARRIQAQTYFIDL
                     PCWAQSEEEDDSPDTQDESQTLLLRATRMDNSDTLWDHLFEDESQQTALPSTLAHYFA
                     QLRGDSPGDALNRQREAFMARWITWAMQQNNGDVLVVCGGWHAPALAKMWRKCPQEMN
                     KPELSSLADGVTGCYLTPYSEKRLDVLAGYLSGMPAPVWQNWCWQCGLQQAGEQLLKT
                     VLTRLRQHKLPASTADMAAAHLHAMALAQLRGHTLPLRTDWLDAIAGSLIKEALNAPL
                     PWSYRGVIHPDTDPILLTVIDTLAGDGFGKLSPSTPQPPLPKDVTCELERTGISLPAE
                     LTLNRFTPDGLAQSQVLHRLAILEIPGVVRQQGSTLTLAGNGEECWKLTRPLSQHAAL
                     IEAACFGATLQEAARHKLEADMLDAGGIGCITTCLSQAALAGLASFSQQLLEQLTLLI
                     AQENQFAEMGQALEVLYALWRLDEISGMQGAQILQTTLCAAIDRTLWLCESNGRPDEK
                     EFHAHLHSWQALCHILRDLHSGVNLPGVSLSAAVALLERRSQAIHAPALDRGATLGAL
                     MRLEHPNASAEAALTMLAQLSPAQSGEALHGLLALARHQLACQPVFIAGFSSHLNQLS
                     DADFINALPDLRAAMAWLPPRERGTLAHQVLEHYQLTQLPVSALQMLLHCPPQAIAHH
                     QQLEQQALASLQHWGVFHV"
     gene            19643..20779
                     /locus_tag="ROH59_001449"
     CDS             19643..20779
                     /locus_tag="ROH59_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDX4803956.1"
                     /translation="MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERYGGLGRSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARRIVHQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSFISLARNFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRYSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSSATPCYDHDTAQALVNVGAQIAAMTPGELASWLAENLQS"
     gene            20776..22779
                     /locus_tag="ROH59_001450"
     CDS             20776..22779
                     /locus_tag="ROH59_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HDX4803957.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHEN
                     GALIATFSDGVRTQLANGQALKEAQCTCGASGMCRHRVMLVLSYQRLCATAQPTEKKE
                     EEWDPAIWLKELANLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRS
                     SIRFARCDCIEGTLCEHVVLAVQAFVEAKTQQAEFTHLIWQMRSEHVTSSDDPFASEE
                     GKTCRQYVQQLSQALWLGGISQPPIHYEAAFSRAQQAAERCNWRWVSESLRQLRASVD
                     AFHARASHYHAGECLRQLAALNSRLNCVQEMARRDSIGEVPPMPWRTVVGAGIAGEAK
                     LDHLRLVSLGMRCWQDIEQYGLRIWFTDPDTGSILHLSRSWQRSEQENSPAATRRLFS
                     FQAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVAL
                     REYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNVLTLS
                     LPASACSPFAVERMAALLQQTDDPVSLVSGFVSFVEGQLTLEPRVMMTKTRAWALDAE
                     TAPVAPLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAIGEAELLANDLTA
                     VGFYRLAHVLGQFRNTESEARVEAMNNGVLLCEQLFPMLQQQG"
     gene            22904..23365
                     /locus_tag="ROH59_001451"
     CDS             22904..23365
                     /locus_tag="ROH59_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HDX4803958.1"
                     /translation="MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAIT
                     YVYKGDKVLKQSSETKIQFASIGATTKEDAARTLEPLSAKYKNIAGVEEKLTYTDTYA
                     QENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK"
     gene            complement(23406..23876)
                     /locus_tag="ROH59_001452"
     CDS             complement(23406..23876)
                     /locus_tag="ROH59_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HDX4803959.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPALEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKS"
     gene            complement(23923..24642)
                     /gene="yehT"
                     /locus_tag="ROH59_001453"
     CDS             complement(23923..24642)
                     /gene="yehT"
                     /locus_tag="ROH59_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HDX4803960.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(24639..26324)
                     /gene="btsS"
                     /locus_tag="ROH59_001454"
     CDS             complement(24639..26324)
                     /gene="btsS"
                     /locus_tag="ROH59_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HDX4803961.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            26546..27277
                     /gene="mlrA"
                     /locus_tag="ROH59_001455"
     CDS             26546..27277
                     /gene="mlrA"
                     /locus_tag="ROH59_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HDX4803962.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRT
                     WIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQTLLAILDGVLINYISICLASARKK
                     QGKDALVVGWNIQDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFEGRTLLVWCGD
                     NRTSAQQQQLTSWQEQGHDIFPLGI"
     gene            27337..27444
                     /locus_tag="ROH59_001456"
     CDS             27337..27444
                     /locus_tag="ROH59_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HDX4803963.1"
                     /translation="MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG"
     gene            complement(27425..28156)
                     /gene="yehW"
                     /locus_tag="ROH59_001457"
     CDS             complement(27425..28156)
                     /gene="yehW"
                     /locus_tag="ROH59_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HDX4803964.1"
                     /translation="MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVIGFGLKPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQAFSQHAK"
     gene            complement(28161..29087)
                     /gene="yehX"
                     /locus_tag="ROH59_001458"
     CDS             complement(28161..29087)
                     /gene="yehX"
                     /locus_tag="ROH59_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HDX4803965.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMALLGLEPNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLQGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLAMLTHPANDFVRQFFGRSELGVRLLSLRSVADYVRREERAEGEALEERMTLRDALS
                     LFVARGCEVLPVVNTQGQPCGTLHFQDLLEEA"
     gene            complement(29080..30237)
                     /gene="yehY"
                     /locus_tag="ROH59_001459"
     CDS             complement(29080..30237)
                     /gene="yehY"
                     /locus_tag="ROH59_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HDX4803966.1"
                     /translation="MTYLRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTLWMLVGVGCAWLTACFIPAKKGSIFALILAQFVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGTLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGVQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKRND"
     gene            complement(30244..31161)
                     /gene="osmF"
                     /locus_tag="ROH59_001460"
     CDS             complement(30244..31161)
                     /gene="osmF"
                     /locus_tag="ROH59_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HDX4803967.1"
                     /translation="MPLSKVWAGSLVLLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNVQ
                     QGYEKVKKLDAEQNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTF
                     KLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLKEYPQMAQWLQPVFASLDEKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWTK"
     gene            complement(31351..33648)
                     /gene="bglX"
                     /locus_tag="ROH59_001461"
     CDS             complement(31351..33648)
                     /gene="bglX"
                     /locus_tag="ROH59_001461"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HDX4803968.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSIMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKS
                     GKVTMEELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKAEFELL"
     gene            33844..35559
                     /gene="dld"
                     /locus_tag="ROH59_001462"
     CDS             33844..35559
                     /gene="dld"
                     /locus_tag="ROH59_001462"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDX4803969.1"
                     /translation="MSSMTTTDNKAFLNELSRLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            complement(35598..36530)
                     /gene="pbpG"
                     /locus_tag="ROH59_001463"
     CDS             complement(35598..36530)
                     /gene="pbpG"
                     /locus_tag="ROH59_001463"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416638.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HDX4803970.1"
                     /translation="MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(36704..37291)
                     /locus_tag="ROH59_001464"
     CDS             complement(36704..37291)
                     /locus_tag="ROH59_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HDX4803971.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            37461..38039
                     /locus_tag="ROH59_001465"
     CDS             37461..38039
                     /locus_tag="ROH59_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX4803972.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDNQA"
     gene            complement(38169..38930)
                     /locus_tag="ROH59_001466"
     CDS             complement(38169..38930)
                     /locus_tag="ROH59_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4803973.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTA
                     REVVSHGVRAEIVQLDLGNLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDDGDVKPGAEPSIPLRRFGATHEIA
                     SLVVWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(38983..40419)
                     /gene="mdtQ"
                     /locus_tag="ROH59_001467"
     CDS             complement(38983..40419)
                     /gene="mdtQ"
                     /locus_tag="ROH59_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HDX4803974.1"
                     /translation="MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTA
                     LPTALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAVATQD
                     GPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNR
                     AEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIAT
                     DRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLSALTNHQTKALKLNP
                     VALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAV
                     NDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRE
                     RANGLLLQGQWLDASIQLTGALGGGYKR"
     gene            40643..40726
                     /gene="yohP"
                     /locus_tag="ROH59_001468"
     CDS             40643..40726
                     /gene="yohP"
                     /locus_tag="ROH59_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HDX4803975.1"
                     /translation="MKIILWAVLIIFLIGLLVVTGVFKMIF"
     gene            complement(41114..42064)
                     /gene="dusC"
                     /locus_tag="ROH59_001469"
     CDS             complement(41114..42064)
                     /gene="dusC"
                     /locus_tag="ROH59_001469"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HDX4803976.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQQCMAISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIDKLR"
     gene            42303..42701
                     /locus_tag="ROH59_001470"
     CDS             42303..42701
                     /locus_tag="ROH59_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDX4803977.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            42698..43393
                     /locus_tag="ROH59_001471"
     CDS             42698..43393
                     /locus_tag="ROH59_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HDX4803978.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            43523..44407
                     /gene="cdd"
                     /locus_tag="ROH59_001472"
     CDS             43523..44407
                     /gene="cdd"
                     /locus_tag="ROH59_001472"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDX4803979.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDAT
                     SATLKALGCHNIDRVLLA"
     gene            44557..45276
                     /gene="sanA"
                     /locus_tag="ROH59_001473"
     CDS             44557..45276
                     /gene="sanA"
                     /locus_tag="ROH59_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HDX4803980.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            45279..45518
                     /locus_tag="ROH59_001474"
     CDS             45279..45518
                     /locus_tag="ROH59_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HDX4803981.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR"
     gene            45712..46950
                     /gene="preT"
                     /locus_tag="ROH59_001475"
     CDS             45712..46950
                     /gene="preT"
                     /locus_tag="ROH59_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /protein_id="HDX4803982.1"
                     /translation="MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDAPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPG
                     GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVG
                     LSSGSGLSLFEHSDVEIAVDFLQRARQAQGDISIQQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFTSARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELT
                     IAADKIILAVGQHAELAAFSALEPQRNTIETQHYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAGAIHHYLEGACSC"
     gene            46944..48179
                     /gene="preA"
                     /locus_tag="ROH59_001476"
     CDS             46944..48179
                     /gene="preA"
                     /locus_tag="ROH59_001476"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HDX4803983.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGS
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANHNIVPAEDLDRSYI
                     VYPHINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IDLGEVKFKKGEKEHPVTL"
     gene            complement(48422..49432)
                     /gene="mglC"
                     /locus_tag="ROH59_001477"
     CDS             complement(48422..49432)
                     /gene="mglC"
                     /locus_tag="ROH59_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HDX4803984.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFIALGSFRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(49448..50968)
                     /gene="mglA"
                     /locus_tag="ROH59_001478"
     CDS             complement(49448..50968)
                     /gene="mglA"
                     /locus_tag="ROH59_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
                     /protein_id="HDX4803985.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANE
                     AINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     MRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA
                     ELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQSEILRLASLHL"
     gene            complement(51029..52027)
                     /gene="mglB"
                     /locus_tag="ROH59_001479"
     CDS             complement(51029..52027)
                     /gene="mglB"
                     /locus_tag="ROH59_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HDX4803986.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK"
     gene            complement(52307..53347)
                     /gene="galS"
                     /locus_tag="ROH59_001480"
     CDS             complement(52307..53347)
                     /gene="galS"
                     /locus_tag="ROH59_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HDX4803987.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGTGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMAKLATELALQGAADNIDPRASHCFMPTLVRRHSVATRQN
                     AAAITNSTNQAM"
     gene            complement(53489..54646)
                     /locus_tag="ROH59_001481"
     CDS             complement(53489..54646)
                     /locus_tag="ROH59_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HDX4803988.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     QDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVEAINNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVIINLPAIALQWQLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLSLFMQFDR
                     LELLAFVIPVWLANIFFSVIWLRYFRQGPVEWLWRQLTLRAAGPTISKTSR"
     gene            complement(54663..55331)
                     /gene="folE"
                     /locus_tag="ROH59_001482"
     CDS             complement(54663..55331)
                     /gene="folE"
                     /locus_tag="ROH59_001482"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDX4803989.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            55589..56425
                     /gene="yeiG"
                     /locus_tag="ROH59_001483"
     CDS             55589..56425
                     /gene="yeiG"
                     /locus_tag="ROH59_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDX4803990.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEQVANDDGYDLGQGAGF
                     YLNATQPPWATHYQMYDYLRDELPALIQSQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSTYLGEDKNAWLEWDSCALMYASNAQDAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYL
                     LK"
     gene            complement(56457..58448)
                     /gene="cirA"
                     /locus_tag="ROH59_001484"
     CDS             complement(56457..58448)
                     /gene="cirA"
                     /locus_tag="ROH59_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HDX4803991.1"
                     /translation="MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNL
                     KDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     VDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWSGTVTVDTTVQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNS
                     TTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQN
                     YSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGKYTLPLTAINQFLTV
                     GGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGE
                     HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPE
                     TSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFET
                     GANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLS
                     DLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVT
                     KDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF"
     gene            complement(58740..60209)
                     /gene="lysP"
                     /locus_tag="ROH59_001485"
     CDS             complement(58740..60209)
                     /gene="lysP"
                     /locus_tag="ROH59_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HDX4803992.1"
                     /translation="MGSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            complement(60414..>61284)
                     /locus_tag="ROH59_001486"
     CDS             complement(60414..>61284)
                     /locus_tag="ROH59_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4803993.1"
                     /translation="LRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQ
                     LFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNYILPA
                     VIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELV
                     VFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSE
                     AIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALR
                     RFLDYCDPANVPR"
BASE COUNT        15208 a        16160 c        15329 g        14587 t
ORIGIN      
        1 aaaaccaggg tggcaaatta atcgtagcga tttaacacga ttcgacgttt gctatcgcta
       61 tctgcagcaa tcacttccgt cgttacacct ttaactggcg aagaaacctg atgacgggta
      121 tcaacattat acgttaactg accacaatgc tgttgaggtt gaccattaac catagccata
      181 ctgcatgtcg ggggactgat cctaccatta atcgttaatg tggcagtttc tgaagagaac
      241 gcgggagaag ccaatccata ggcaagaaaa ataattcctg acagccagta cttattcatt
      301 gaacgttatc cctgtagtaa aggttatgcc tggaaagaat gagtgcataa caaactatag
      361 ctgtacatcc actacacagc cacgaaggat gataatgaag catcgccggt acgatcaatc
      421 gactttgtag agtttcggac gaaggtccgc agaatattcg caacattaaa taagtgttca
      481 ttaatgttgc aaaaacaaat acaccgcatc aatgtaacat ctctgcggtg tatgaagaat
      541 aaccagaatg gttaatacgc gttagaccgc gcggaaggaa atctcgccag gaatgacttc
      601 accctgccag tagagctgag ctgcaacgcg gtcagccagc tggcggtaga tagcggtaaa
      661 ttcgctctca ggacggctga taaccgttgg cgtgccttta tcgagatcct cacgtaagga
      721 gatgtgtaac ggcatctgcc ccagcagctg cgtgtggtat ttctcggcca gtttctctgc
      781 accaccggta ccgaaaatcg gctcatggtg accacagtta ctgcaaatat gcacactcat
      841 gttctcgaca ataccgagca ccggaacctc gactttctcg aacatcacaa tgcctttttt
      901 cgcatcgatc aacgcgatgt cctgcggggt ggtgaccact accgcgccag ttactggaat
      961 gttttgtgcc agtgtcaatt gaatgtcacc ggtacctggc ggcatatcaa gcaccagata
     1021 gtcgagatcc ggccacaagg tttcctgcaa catttgcatt aacgccttgc tcgccattgg
     1081 gccacgccac accatcgcat tgtcgtcagt gaccagataa ccaattgaat tggttgccag
     1141 gccatgagac ataatcggtg ccatatgggt accgtccggc gaagttggac gctgattttc
     1201 tgcgcccagc atggtaggga ttgatgggcc gtagatatcg gcgtccagaa tgccgacttt
     1261 cgccccttct gccgccagtg ccaacgccag gtttaccgcc gtggaggatt tacccacgcc
     1321 acctttaccg gaactgaccg cgataatgtt cttcacgccg ttaattcccg gctgattctt
     1381 cacgcgtttc agagtggcta tgttatgcga cagtttccag tcgatagctt tcgctccggt
     1441 gatgcgcagc agttcggcgc tacattgctc ttttaactct tcgaacgcgc tatgccagac
     1501 gaatggcatg accagttcca catgcagcgt gtcgtccatc caggcgacat ggtgcaacgc
     1561 tttcagcgtt gtgaggttat gcttcagggt tgggtgctga aaattggcca gtgtcccggc
     1621 gaccattgcg cgcaaggctt ctggtgattt ggcctgggat tgttcgttca tcccgactcc
     1681 ttttttgtat agataaacca tcagctgata gtttacctga agaatataga gaagtactta
     1741 cttaacattt tcccatttgg tactatctaa gcccttttca ctattaagaa gtaatgccta
     1801 ctatgactca agtcgcgaag aaaattctgg tgacgtgcgc actgccgtac gctaacggct
     1861 caatccacct cggccatatg ctggagcaca tccaggctga tgtctgggtc cgttaccagc
     1921 gaatgcgcgg ccacgaggtc aacttcatct gcgccgacga tgcccacggc acgccgatca
     1981 tgcttaaagc tcagcagctt ggtatcaccc cggagcagat gattggcgaa atgagtcagg
     2041 aacatcagac tgatttcgca ggctttaaca tcagctatga caactatcac tcgacgcaca
     2101 gcgaagagaa tcgccagttg tcagaactta tctactctcg tctgaaagaa aacggtttta
     2161 ttaaaaaccg caccatctct cagctgtacg atccggaaaa aggcatgttc ctgccggacc
     2221 gttttgtaaa aggcacctgc ccgaaatgta aatccccgga tcaatacggc gataactgcg
     2281 aagtctgcgg cgcgacctac agcccgactg aactgatcga gccgaaatcg gtggtttctg
     2341 gtgctacccc ggtaatgcgt gattctgaac acttcttctt tgatctgccc tctttcagcg
     2401 aaatgctgca ggcatggacc cgcagcggtg cgttgcagga gcaggtggca aataaaatgc
     2461 aggagtggtt tgaatctggc ctgcaacagt gggatatctc ccgcgacgcg ccttatttcg
     2521 gttttgaaat tccgaacgcg ccgggcaaat atttctatgt ctggctggac gcaccgattg
     2581 gctatatggg ctctttcaag aatctgtgtg acaagcgcgg cgacagcgta agcttcgatg
     2641 aatactggaa gaaagattcc actgccgagc tgtatcactt catcggtaaa gatatcgttt
     2701 acttccacag cctgttctgg cctgccatgc tggaaggcag caacttccgc aagccgacca
     2761 acctgtttgt tcacggctat gtgacggtga acggcgcgaa aatgtccaag tctcgcggca
     2821 cctttattaa agccagcacc tggctgaatc attttgacgc cgacagcctg cgctactact
     2881 acaccgccaa actgtcatcg cgcattgatg atatcgatct caacctggaa gatttcgttc
     2941 agcgcgtgaa tgccgatatc gtgaacaaag tggttaacct ggcgtcccgt aacgctggct
     3001 ttatcaataa gcgttttgac ggtgtgctgg caagcgagct ggctgacccg cagttgtaca
     3061 aaaccttcac tgatgccgct gaagtgattg gcgaagcgtg ggaaagccgt gaatttggta
     3121 aagctatccg tgaaatcatg gcgctggctg acctggctaa ccgctatgtc gatgaacagg
     3181 ctccgtgggt ggtggcgaag caggaaggtc gcgatgccga tctgcaggcg atttgctcaa
     3241 tgggcatcaa cctgttccgc gtgctgatga cttacctgaa accggtactg ccgaaactga
     3301 ccgagcgcgc agaagcattc ctcaatacag aactgacctg ggatggtatc cagcaaccgc
     3361 tgttgggcca taaagtgaat ccattcaagg cgctgtataa ccgcatcgat atgaaacagg
     3421 ttgaagcact ggtggaagca tccaaagagg aagtaaaagc cgctgccgcg ccagtaactg
     3481 gcccactggc agatgatccg attcaggaaa ccatcacctt tgacgacttt gctaaagttg
     3541 acctgcgcgt ggcgctgatt gaaaacgcag agtttgttga aggttctgac aaactgctgc
     3601 gcctgacgct ggatctcggc ggtgaaaaac gcaatgtctt ctccggcatt cgttctgctt
     3661 acccggatcc gcaagcacta attggtcgtc acaccattat ggtggctaac ctggcaccac
     3721 gtaaaatgcg cttcggtatc tccgaaggca tggtaatggc tgctggtcct ggtgggaaag
     3781 atatcttcct gctaagcccg gatgccggtg ctaaaccggg tcatcaggtg aaataatccc
     3841 ccttcaaggc gctgcatcga cagcgccttt tctttataaa ttcctaaagt tgttctcttg
     3901 cgattttgtc tctctctaac ccgcataaat actggtagca tctgcattca actggataaa
     3961 attacaggga tgcagaatga gacactttat ctatcaggac gaaaaatcac ataaattctg
     4021 ggcggtggag cagcaaggca acgagttaca tgtcagttgg ggcaaagtcg gcactaacgg
     4081 gcaaaaccag gtaaaaagct ttgctgatgc tgcggcggcg gaaaaagcaa agcttaagct
     4141 gatcgcagag aaaacgaaaa aaggctatgt ggaaaatgct tctgcaaacg tgcatatcac
     4201 ccccatcacc aaagccactc ctgaagttga aacttctcct gagagtaaaa accaacgccc
     4261 ctggctggct gatgatgcgg tcattcggct aactgacgat attaatcgat ttgcttttcc
     4321 tcatcgctct cgccccagag agatcaatta tctgcacaaa gatagtcaaa tatggcagcg
     4381 catcgcgaat aacaccaggg catatgatcc cgccaacaat taccgttctt atccagaaaa
     4441 ctggcagcag gcttttgctg agttacaaag gcgaattctg gataatcaac agacagggag
     4501 tgcgcaatct gatgcggcat tgctctggag tttctggaat tcttactctg cagatgaact
     4561 agtcgatgac ttaatcattc gctgtggtat ggaaagtgcc gttgaaattg cccttctcgc
     4621 tcttcaactg agatataaac cagtaaaagg cgcagtaacc accatcattc cacctaatca
     4681 cgaagcagaa tcgctaccga gttggcatca acgcctatgt catcatcttt cactcgcttc
     4741 agaagatgag tggcaacgct gtgtagataa agtactcgcg gctattacga cgctatcccc
     4801 agcacggcaa ccttttgcgg cgttactgct ccctgaacgc ccggatattg ccaatgctat
     4861 ggctctacgc tatgcagatc aaaacgttcc ggcgatgacc tggttaagac tggtagtaac
     4921 cgatgaagcc gctctgactg cagccgaaaa atacgacttt ccaccgttat atcgtgattt
     4981 tcgcgcttat ctggcaatgt tgctggcaaa taatggggtg agcggtgtaa gccggatact
     5041 tactgagttt gtggaagagc attctgacaa tcccacttat ctcttcgagc gcatcagcga
     5101 gactgaagat cttgtcaaat ggttatggaa aacgaatcac ccggatgcga ttcaaattct
     5161 gatcctcggt gtaattggca agaaaaagca cctggaatac ttaagcaaag catgtcaaaa
     5221 acatcccgct gcggctattg ccgcttatgc aactttgctg gcaatacatg aagataaaga
     5281 gtggcataaa gcgcttgtca aattgattac catcacgcca gagttagtat gcgacgtcat
     5341 tccctgggtt agtgctaaag cggcaggcat cttatctgaa tgtcgtcctc agtcagtagc
     5401 tgaagaatgt gagtatgcca ctgcggatat gttgccagag ctgtttgttt cgccgccctg
     5461 gatgactaaa gagaaaaaga aaaattcgcc ggtgtttgat cttcctgtac tgccagttcc
     5521 ttctgtttct gacgtcactc cagagattgc caaaaaacta acccgtacat accttgtcac
     5581 ccgcttccag caaatagccc aacagcaggc aacaaaacaa atattgttta ccgacctgcc
     5641 gctgatggaa aaagcaagct gggagagaca cttagtcccc ctcacaccag aacagcaaat
     5701 tctgtggtgt ctgggttttg acaaatggcg ggagagcgga gaaaaaatat acgaaaaaat
     5761 tccggcgcca caaagtgccg ttgatgccct gctacgcttc gattttccag cactcaatgc
     5821 tgaatttgcg caataccata acaatgctta caaaagctgg aatctcattg ccctctgtta
     5881 tctacctggt caacaggcca tttcttttct taaccagata gtcaaagaag ataactactc
     5941 tggtgaggga tatattctgg ccatttttgg tagcgccgcc attcctgcat ttatgacctg
     6001 cctgcaacgt gagccacaac ggttgtggtt tttcaccttc ttccttggtg tcaatgaact
     6061 ggcattgcca atggcgcaac gacttcagaa aaaaatgtcg tatgaagatg cacgaaactg
     6121 gctaacggat tacccacgcc atgccgccgc cgggctactt cctgtggcac tgggcaaaca
     6181 aggaaaagat cgtgattgtg cccgccaggc gctccgtctg ctggtgaatt taaaccagcg
     6241 agaaacgatt gaggaaatcg cccaaggata caaccaacct gatgttttag ctgcgctggc
     6301 aacattattt gatagcgagc cgctggaaga atatcccgct aaaatcgccc cactgcccgg
     6361 cttttatcag ttcaccttat ggcgcagacc acggcttaaa agtaacaacc agcctctgcc
     6421 agatgacgct atgcgccacc tcggcataat gctgagcttt ccacgcgaca ttacccccta
     6481 cgcagggctt gcgatcatca aagaaacctt cacccgcgaa tcactggctg aatttggctg
     6541 ggatctgtat accgcctgga cagaagctgg cgcacccgca aaagaaaact gggcatttac
     6601 ctcgctgggg attttaggca atgacgacac cgcgcgtaaa ttaaccccgc tcatccgcac
     6661 ctggccgggt gaatcccagc ataaacgcgc ggtttacggg ctggatgtgt tagccagtat
     6721 cggtagcgac attgcgctaa tgttgcttaa tggcattgcg aaaaagatta aattcgttgc
     6781 attacaggaa catgcctgcg acaaaatcaa catggtcgct gaaaatcgcg ggctgactat
     6841 ggctgaactg gaagaccgcc tggcaccgga tttaggactt gatagcagtg gctcgttgac
     6901 actggatttc ggcccacgtc aatttaccgt tggttttgac gaaactttaa aacccgtggt
     6961 tcgcgacgca aacggcaaag ttctgaaaga tttacccaaa ccaaatcaga gcgatgataa
     7021 aacgctggca actgacgcgg ttaatctctt caaacagttg aaaaaagatg tacgcgccat
     7081 agccagccag cagattgatc gtctggagca ggctatgtgc cagcgcagac gctggacggc
     7141 agagcagttc cgcctgttcc tggtggagca tccgctggta cgtcacttaa cccgacggtt
     7201 gttatggggg gtatatactg aggaaaacac gctgattgcc tgcttccggg tcgcagaaga
     7261 cagcacttac agcgatgcgc aggatgagct atttacgttg ccagcaggaa acatcggtat
     7321 tccgcatgtg ctggaaatat ctcctgaatc cgccgctgca tttgggcaaa tttatactga
     7381 ttacgaacag cttcctccgt tccgccaact cgatcgtggt tattaccacc ttgctgataa
     7441 tgaacgtgat tcccatgaat tgatacgctg gcaaggacgt ctttgccagg ccgggcgcat
     7501 tgtcgggctg gaacgccgag gctggcaacg tctggaagaa agcggcagcg tttacgcgat
     7561 gcgcaaatct actccttatg gcgatctcga acttgaaaca gaaccttttt cattaattta
     7621 tggtgaaacg gggtatggcg accagctacc ggttgaaagc gtaaaaatca cctcgcctga
     7681 taatcgctac ggtaaacaat cctcactcac tttttccgcg ctcgacgaca tcaccgccag
     7741 cgaactcatt aacgacattg aatcactgtt tgattaaaag gatttagcaa tgaaaaccta
     7801 tatttatcag gacgaaaaat cacataaatt ctgggcagta gagcagcagg aaaatgaact
     7861 gcatatcagt tggggcaaag tcggcactaa cgggcaaagc cagataaaaa gctttgctga
     7921 tgcggcggcg gcggaaaaag cggagctgaa gttgattgcg gagaaaacga aaaagggcta
     7981 cgcagaagaa gtatccgtga cgacaccgac atctgccccc gtccaggtta tcgcatgctc
     8041 tgaaaaagcc cctttgccgc aagacaaacc accatttgct gaagaccacc ttccctggct
     8101 ggcagacgac gcccaaatca ttttaccgac agaggtcgca ccaaccacac taagtcatcg
     8161 acgctggcct ggcgattctg tgccacagga gaatgaatta actctgctac gctccgtcgc
     8221 cgcgcatact caccggcgtt ttaaaaaggt gatcaccttc gattacagca cctgttcact
     8281 ggactggcag caggcgatta cacaagcagt gggccttatc gactcaccga ttagcaccgc
     8341 actaccaccg atggttctgg cggtactggt tgcgctggaa caaggcttca atcgcaacga
     8401 tcacgaagag ttaatggatc aaattgtcca ggagggtggt ctggaatatg ccactgaggt
     8461 tgtcattgca ttgcaagcca tccgctttga ctggaattat gatgcccacc tcattacgtt
     8521 taccccggat aacaagcagc ctggctatct gtcacgcttt gcctcggttg aaatgcgtct
     8581 gcgtaaacat ctctcactag caaatgacga tgtatggcag cgctgcgccg acaaactgat
     8641 tgcagctctc ggaaacatac ccgcctggca tcagccgctg gttgcgttat tgttgccgga
     8701 aaaacaagat gtgagccatg agattgccag acgtctttgc ggacaaaaag ggttatatgc
     8761 gctggaatgg ctaaaactaa cggccgccga cgagcaggta ttggcagaac tggggaaata
     8821 ctatccagga cagccagggc aggtatttga tgattattac ggcggtaaaa tctggtgcgc
     8881 aacgatactc aaggagcaag gtgtcggtgc gctggcccgt tttgctcctt acgctgctgg
     8941 tgacacatgt ggtgaagtgt tgatgcatat caaccacccg caggcactta cactacttat
     9001 ccatgcaagc gagcagggaa agcgttgcca cgatcgcatg acaaagactt tcgttcgctt
     9061 tccacatgca gcgctggcgg cattagcaga acttctggca caaaaagatc aaaagcgttg
     9121 gcgcatgatg ctaatgacaa tgcttatctc acaaccaaca ttagcagagc gagtaatccc
     9181 ctggctctca acacccgcag ttgccgtact gaaatcatgc cagcaacaac tgacacagcc
     9241 ctcaaaccat gccagcgctg atatgctgcc tgccgtatta gtctcaccgc cctggctttc
     9301 gaaaaagaaa aaatctgtaa tgccggtatt ggatttaacg ccattaccgc tggagtcatg
     9361 ctgcacattg accgagacgg cagaaaaaga gattcatgca aggcatcgct ggcacgcaca
     9421 tcaaatagac atcggccaaa aagaggatat tcagaactac ctgacacgtc tgggtttcaa
     9481 tcgctggaat aatggccagt atatgaaagc gtctgatgct gttgtagaac tctggcagag
     9541 gggagattat tctgcgctaa tcagcgaatt taaaaccttc tggcactcct atcaacggga
     9601 atggcagctt tacatgttag ccgccctgcc tatcgaaaaa acagcgcagg cgtggaatgt
     9661 cctcagtaaa gagccacacg tcggtgtcga gtttgtcatg acgcacctgc aactcgctgg
     9721 gttacagggt tttattcact ccttttcacg ctatccacaa gaagctctgc ctgtagcaca
     9781 atattttgcg gctatcgaat tagcgccact gatcgcccgc gccttcaaca aactcaaaac
     9841 attacgacaa gacgcccgta tctggctgct gaaatacccg gaacacgcca ttaccggcct
     9901 gctgcctgca gcgctcggca aaaccggtga agcacaggac aacgcccgtg ctgccttgcg
     9961 tatgcttacc gaaaacggtc atcagccatt gctgcaagaa atcgcccggc gttataacca
    10021 gccggaagta accgatgcgg tgaacgctct acttgcgctc gatcccttag ataatcaccc
    10081 gacaaaaatc cccactcttc cgacctttta tcagccatcg ctctggacgc gcccgttatt
    10141 aaaagcaaac gcccaatcac tgcctgatag cgcactcctc cacctcggtg aaatgctccg
    10201 cttccctcag gaagaggcac tgtatccagg attattgcag gtgaaagatg cctgtaccac
    10261 cgactcactg gctgaatttg cctgggatct gtttaccgcc tggcagaccg ctggcgcgcc
    10321 gtcgaaagag agttgggcgt tcactgcgtt aggcgttctc ggtaacgatg acaccgcccg
    10381 caaactgacg ccattaatcc gtgcctggcc tggcgaatcc cagcataaac gtgccaccgt
    10441 tgggttggat atcctcgccg ctatcggtag tgatatcgcc ctgatgcagc ttaacggcat
    10501 cgcccagaaa ctgaaattca aagcattaca ggagcgggca aaagaaaaaa tagccaacat
    10561 tgccgagagc cgcgaactca cggtggcgga gcttgaagat cggttagcac cggatctcgg
    10621 tctggatgat aacggttcgt tgctgctgga tttcggccca cgccagttca ccgtcagctt
    10681 tgatgaaacc ttaaaaccgt ttgtgcgtga cgcttccggc agtcgtctga aagacctgcc
    10741 caaaccaaac aaaagcgatg atgaatcaca ggcgaacaat gctgttaacc gctacaaatt
    10801 gctgaaaaaa gatgcgcgta ccgtcgccgc ccagcaggta gcaaggctgg aatccgccat
    10861 gtgcctgcgt cgccgctggt caccggaaaa ctttcagctc ttcctggttg agcatccgct
    10921 ggtccgccac ttaacccgcc gtctgatttg gggcgtttat agcgccgaaa accagctact
    10981 ggcttgcttt cgcgtagcgg aagataacag ctacagcacc gctgacgatg atcttttcac
    11041 cctgccggaa ggcgatatct ctattggtat tcctcacgtt ctggaaatat caccgacgga
    11101 tgctgccgcc ttcgggcagc tttttgccga ctacgaactg ttaccaccgt tccgccagct
    11161 tgatcgtaac agttacgcgc tgacagaagc cgagcgcaat gccagcgaac tgacacgctg
    11221 ggcaggcaga aaatgcccga gtggtcgggt aatggggctg gcaaataaag gctggatgcg
    11281 tggtgaaccg caggacggtg gctggatcgg ctggatgatc aaacctctgg gccgctggtc
    11341 gttaatcatg gaaatcgatg aaggttttgc ggtcggcatg tcgccagccg aactcagtgc
    11401 cgagcaactc ttaagcaagc tgtggctatg ggaaggcaaa gcggaaagct atggctgggg
    11461 gagtaattca acacaggaag cgcagttctc cgtactcgat gccatcaccg ccagcgagct
    11521 aattaacgat attgaagccc tgtttgaata aggaaagagc atggacaagg aattaccgtg
    11581 gctggcggat aacgcccaac tggaactgaa atataaaaaa ggcaaaacac cactcagcca
    11641 tcgcaattgg ccaggcgaac cggtacctgt tatcactgaa aacatcattc agacactggg
    11701 tgatgaattg ctacaaaaag cagagaagaa aaaaaacatt gtctggcgtt atgaaaactt
    11761 ttcactggag tggcagtccg ccatcacgca ggccatcaac ttgatcggcg aacacaaacc
    11821 ctcaatcacg gcccggacaa tggcggcgct agcctgtatc gcgcaaaatg atagccaaca
    11881 gttgctcgac gaaatcgtcc aacaagaggg gctggaatat gcaactgagg tggtgattgc
    11941 acgccagttt attgtacggt gttatgagag tgatcctctg gtagtaacat tgcaatatca
    12001 gaacgaggac tatggctatg gttatcgctc agaaacctat aacgaattcg atctccgatt
    12061 gcgtaagcat ctctctctgg cagaggaaag ctgctggcag cgttgcgccg acaaactcat
    12121 tgccgcactg ccaggaataa ccaaagttcg ccgccctttt attgcgctga acctcccgga
    12181 aaaacccgaa atcgccaacg agctggtaag ccttgaatgt tcgcaaactc attttcgctc
    12241 aaaagagtgg ttaaaagttg ttgctgatga ccctaaggcg gtgaaagaac tcgcacgcta
    12301 ctggagccag gatatattta gcgatcgaga agccagctac atgtcgcatg aaaaccactt
    12361 cggctacgcg gcctgcgctg cccttttgcg cgaacaagga ctggcagccg ttccgcgcct
    12421 cgcgatgtat gcacataaag aagattgcgg cagtctgctg gtacaaatta accatccgca
    12481 agtcatccgc accttgctac tggtggctga taaaaacaaa cccagcctgc aacgtgtggc
    12541 taaatacagt aaaaacttcc cccatgcgac gctcgccgca ctggcagagc tgctggcgtt
    12601 aaaagccccc cctgcgcgcc ctggttatcc catcatcgaa gacaaaaagc tgcctgcaca
    12661 gcaaaaagca cgtgatgaat actggcatac gctgttacaa acgctgatgg catcgcagcc
    12721 acaactggca gaagaggtga tgccgtgctt atgtacacaa gcccaggcag tggtgaatgg
    12781 ttatttatcg gcatcgccaa aacttgcttt cgagagtact catagcaacg acctgccaga
    12841 aatacttgtt tctccaccgt ggcgaggtaa gaaaaaaacg gcattgctgc gccttgattt
    12901 agtgcctctt gaattagcgc ccaaagcccg ctggcaacca ggcgaacgag agagacttgc
    12961 cgccacagag tctgcccgtt atttcagcac gggatctttt acggaacgca tggaacgaaa
    13021 aagtggtcga gttgtactac aggagctagg ttttggggat gatgtatggc tgttccggaa
    13081 ttatatactg cccggcaaac tggatgcggc gcgcaaatca ttagtgggtc agtggcatta
    13141 ctccccgcgc agagtagagg aaatcaacaa tggctggcac tccacggaag caaaatcagc
    13201 cgaacaggcg cttcgttccg gcgacgttga agcgttaatt aacacctggg aaaatgatag
    13261 ctactcgcat tatcgtcagg aaaagagtgt ctggaacctg tatttattgg cgcagttgcc
    13321 acgtgagatg gctttgactt tctggctgcg tatcaatgag aaaaagcatc tattcgcggg
    13381 tgaggactat tttctcagta tcctcgggtt ggatacatta cctggcctgt tattggcttt
    13441 ttcacatcat ccaaaagaaa catttccgtt aattttaaat ttcggcgcaa cagaactggc
    13501 cctgcccgtt gcccgcgtct ggcgacgttt cgcggcgcag cgtgatctgg ctcgccagtg
    13561 gattttacaa tggccggaac atacggctac tgcacttatc cctcttgtct ttacaaaacc
    13621 cagcgataat agcgaagctg cattacttgc cctgcgttta ctgtatgaac aagggcatgg
    13681 cgaattactg caaaccgtgg caaaccgctg gcagcgtaca gatgtatggc ctgccctgga
    13741 gcaattactt aaactgggtc caatagaaat ttacccggca cgtattccaa aagctcctga
    13801 tttctggcat ccgggaatgt ggtccaggcc gcgccttatc actaataatc agcctgttac
    13861 cgatgacgct ctggaaatta tcggcgaaat gctgcgcttt acccagggcg gacgttttta
    13921 tggcggactg gaacagctga aaacgttttg ccagccgcaa acgctggcag cttttgcctg
    13981 ggatcttttc accgcgtggc aacaagctgg tgcccccgca aaagacaact gggcatttct
    14041 ggcgttaagt ctctttggtg acgaaaccac ggcacgagat ctgacgacac agatcctcgc
    14101 ctggccacaa gaaggcaaat ctgcccgtgc tgtcagtggc ctgaacatcc ttaccctgat
    14161 gaataatgat atggcgctga tacagctgca ccatatatcc caacgggcga aatcccgctc
    14221 cttacgtgat aacgcggcgg aatttcttca ggtggtcgca gaaaatcgcg ggctaagcca
    14281 ggaagagtta gcggacagat tagtcccaac attgggcctt gatgatccgc aggcgttgag
    14341 ttttgatttt ggtccccggc agtttaccgt tcgcttcgat gaaaacctca acccggttat
    14401 ctttgatcag caaaacgttc gccagaaaag tgttccccgg ttgcgcgccg atgacgatca
    14461 actgaaagcg cccgaggcac tggcccgact aaaagggcta aaaaaagatg ccactcaggt
    14521 gagcaaaaac ctgctcccac gtcttgaagc agccctacgt atcacccgcc gctggtcgct
    14581 ggcagatttt cattctctgt ttgttaatca tccctttacc cgcctggtta cccagcgatt
    14641 aatatggggg gtttatccgg caaatgaacc gcgtcgttta ctcaacgcct ttcgtgtggc
    14701 cgcagagggg gagttctgca atgcacaaga tgagcccatt gacctgcctg cggatgctct
    14761 gattggcatt gcccacccgt tagaaatggc agcagaaatg cgcagtgaat ttgcacagct
    14821 ttttgccgat tacgaaatta tgccgccttt tcgccagttg gcgcggcgca cggtgctgct
    14881 cacacctgac gagtcagcca gtaacagcct gactcgctgg gaaggtaaat ccgctaccgt
    14941 tgggcaactt atgggaatgc gatacaaagg ctgggagtca ggctatgagg acgcatttgt
    15001 ctatgactta ggtgcgtacc ggctggtcct taagttttca cccggtttta accactacaa
    15061 tgttgatagc aaagcgctaa tgagcttccg ttctcttcgg gtttaccgtg acaataaatc
    15121 cgtcactttt gccgaacttg atgtgtttga tttgagtgag gcattaagcg cacctgacgt
    15181 cattttccat taaaacacag cgggcagtga tgcaactgcc cgttatcaac acgacctacc
    15241 agcgggggaa gcgatgatcg tgcaaaaaga gctggttgct atttacgatt atgagatccc
    15301 tgtacctgaa gagccgtttt ccttcagact tgaaatccat aaatgctctg aattatttac
    15361 aggttccgtc tatcgactgg agcgattccg gctacatcca acatttcatc aacgtgatcg
    15421 agaagatgcc gaccactaat aaatgatgcg ttgatttata taagagatga gtttattgat
    15481 gagcggaaat tacgaggtga atcacatgaa acagtaatag caatttttaa ttgtgaacta
    15541 cagaatatat tcaaccaaga aatagaataa tatactctag ataattcaag tcgcaggaag
    15601 gcgataagcg agtgagtccc caggagctta ctaaagtaag tgacaggggt gaacgaacgc
    15661 agtcgcagca catgcaactt gaagtatggc gagtatagct ttattaaagg gggaaacggt
    15721 attccccctt agatgcgttt caatttgccc gttacttcaa caaatcaatc aaccgtaaca
    15781 gagccactaa tagctccagt acagcaatga gcacggttaa cttttgtgtc agcgtgtcca
    15841 tccgctctcc ttttaaggag cgcaacacca gcaccttacc cttacactgc ctgtcgatac
    15901 tggtttacgt atgttggacc acgatgttgc actccggatc aggcaccacc tgcagcacca
    15961 cccgtccggt agccaggact tgaaattggt tcgatccggc gcaacctccc aacagtcagg
    16021 attataaatc tcattatctt aattgcaacg gggtccagcg gtggttataa ttcgttcgtt
    16081 ggaacacgat gttgcacagg ctgcggtgtt aggcctgaaa gtaataaata aaagaacctg
    16141 cctcaccagc aggttttttt attttttgcg atctgctttc cagatatttt ccgctcaaac
    16201 aactaatgcg ccaaacattt attgcgcgta aaatatcgtt tatttcatta atacatttca
    16261 gggatgaata tatgtcaccg cagaataatc acctgcagcg tccgcctgct gctgtgttat
    16321 acgccgttga actggcaaaa ttaaaacaaa atgataacgc accttgcccg cccggttggc
    16381 agttaagttt gcctgcggcc cgtgctttta ttcttggcga cgaagcgcaa aatattcgcc
    16441 gtaaagtggt gattagtccc tctgctgtcg aacgcatgtt agtcactctt gccaccgggc
    16501 gcggtttgat gttggtgggg gaaccgggta ccgcaaaatc tctcctgtct gaattactgg
    16561 caaccgctat tagcggcgat gccgggttaa ccatccaggg cggcgcatct accaccgaag
    16621 atcaaatcaa gtacggctgg aactacgccc tgcttatcaa tcatggtccg tcaacggaag
    16681 cgctggtccc tgccccgctt tacctgggaa tgcgcgacgg caaaatcgtc cgttttgaag
    16741 agataacgcg tactccactg gaagtacaag actgtttatt aggtatgctt tctgacaggg
    16801 ttatgacggt gccggaactc actggtgaag ccagtcaact ctatgctcgg gaaggcttta
    16861 atattattgc cactgccaat acgcgcgatc gcggcgtcaa tgaaatgagt gccgcgctaa
    16921 agcgtcgctt cgattttgaa actgtctttc cgattatgga tttcgcccag gagctggagc
    16981 ttgtcgccag tgcttcggcg cgtttgctgg cccatagcgg cattccgcat aaagtgcctg
    17041 acgcggtact ggagttactg gtccgcacct ttcgcgatct gcgtgccaac ggcgaaaaga
    17101 aaacgtcaat ggatacactg acagcgatta tgtccaccgc tgaagccgtg aacgtggccc
    17161 acgcggtggg cgtccgcgcc tggtttttag cgaatcgagc aggtgagcca gccgatctgg
    17221 tggactgtat tgccggaacc atcgtcaaag ataacgaaga agaccgcgcg cgcctgcgcc
    17281 gttacttcga acaacgtgtt gccacacata aagaagctca ctggcaggct tattatcaag
    17341 ctcgccaccg cctgccgtga ggaaagatgc atgagcgagc cgttaattgt cggcatccgg
    17401 catcatagcc cggcctgcgc ccggctggtg aaatcgttaa tcgaaagcca gcggccacga
    17461 tacgtattga ttgaaggccc ggctgatttt aatgaccggg tagacgaact gtttttagcc
    17521 caccagcttc cggtagctat ttacagttat tgccagtatc aggacggtgc ggcccccggg
    17581 cgtggtgcct ggacgccatt tgctgaattt tcgccggagt ggcaggcgct acaagccgca
    17641 cgtcgtattc aggcacaaac ttacttcatc gatttgcctt gctgggcgca gagtgaagaa
    17701 gaggacgatt cgcctgatac acaagatgaa agccagacct tactgctgcg tgccacccgc
    17761 atggataaca gcgataccct gtgggatcac ttattcgaag atgaaagcca gcaaactgca
    17821 ttaccctcta cgctggcgca ctattttgcc caactgcggg gcgattcccc cggagatgct
    17881 ctcaatcgtc agcgcgaagc ctttatggct cgctggatta catgggcgat gcagcaaaac
    17941 aatggcgacg tgttagtcgt ctgcggcggc tggcacgctc ctgcactggc aaaaatgtgg
    18001 cgcaaatgcc cgcaggaaat gaacaagcca gaattgtcct cgctggcaga tggcgttaca
    18061 ggttgttatc tcacacccta cagtgaaaag cgccttgatg tgctggcagg atacctttcc
    18121 ggaatgcctg ccccggtctg gcaaaactgg tgctggcagt gtggcttaca gcaggcaggt
    18181 gaacaactgc tgaaaacggt tcttacccgt ttgcgccagc acaaattgcc cgcttctacc
    18241 gctgatatgg ctgctgctca tctgcatgcg atggcactgg cacagttgcg cggccataca
    18301 ctacctctac gcactgactg gctggatgcc atagctggct cgctgattaa agaagccctg
    18361 aatgcgccgt tgccgtggag ctatcgcgga gttattcatc ccgataccga tccgattttg
    18421 ctaacggtga tagacacatt agcgggtgac ggattcggta aactttcccc ttctacgcca
    18481 caaccgcctc tgccaaaaga tgtcacctgc gaactggaac gtaccggaat ctctcttccg
    18541 gcggagctta ccttaaatcg ctttaccccc gatggactgg cgcaaagtca ggtgttacat
    18601 cggttggcaa tactggagat cccaggggtt gtgcgccagc agggaagtac gctgacactt
    18661 gcaggcaacg gtgaagaatg ctggaaatta acccgcccgc ttagccagca tgcggcattg
    18721 attgaggccg cctgctttgg tgccacactc caggaagccg cacgccataa attagaagcc
    18781 gatatgctgg acgcgggtgg aatcggctgt atcaccacat gtcttagcca ggcagcgtta
    18841 gcgggtctgg cgtctttcag tcagcaatta ctggaacaac tcacattatt aattgcccag
    18901 gaaaatcaat tcgccgaaat gggccaggcg ctggaagtgc tatatgcctt atggcggctg
    18961 gatgaaatta gcggtatgca aggcgcgcag atattacaaa cgacattatg cgcggccatc
    19021 gatcgcacgc tgtggctatg tgaatccaac ggcagaccgg atgaaaagga gtttcacgct
    19081 cacctgcata gctggcaggc gctttgccat atcctgcgcg atctacatag cggcgttaat
    19141 ttacccggcg tttcgctttc tgcggcggta gccttactgg agcgccgcag tcaggcgatt
    19201 catgccccgg cgctggatcg cggcgcgact cttggcgcac tgatgcgtct ggaacatccc
    19261 aacgccagtg ccgaagcggc gctgacgatg ctggcgcagt tatccccggc acaatccggc
    19321 gaggcgctgc acggtttgct ggcattagcc cgtcatcaac tggcctgtca gccggtattt
    19381 atcgccggtt tcagcagtca tttaaatcaa ctgagtgatg ccgattttat caatgccctg
    19441 cccgatttac gcgcggcgat ggcctggcta ccaccacgag aacgcgggac gctggcgcat
    19501 caggtgcttg agcattacca gctcacacag cttcccgttt cagcgctgca aatgctgttg
    19561 cattgtccac cacaagccat tgcacatcat caacaactcg aacagcaggc actggcatcg
    19621 ctgcaacact ggggagtttt ccatgtctga actgaacgat cttctgacca cccgtgagct
    19681 acaacgctgg cgattaattc ttggcgaagc ggcagaaacg accctttgtg ggctggatga
    19741 caacgcccgg cagatagacc acgcgctgga gtggctgtat gggcgcgatc ctgaacggct
    19801 ccagcgtggt gaacgttacg gtggattagg tcgttcaaat ctcaccaccc ctgagtggat
    19861 taacagcatt cacacgctgt ttccgcaaca ggtgattgag cggctggaaa gcgatgccgt
    19921 gctgcgctac ggcattgaag atgtggtgac gaatctcgac gtgctggaac gtatgcagcc
    19981 ttctgaaagc ctgctacgcg ccgttttgca caccaaacat ctgatgaatc ccgaagtact
    20041 ggctgccgcc cgccggatag tgcaccaggt tgtggaagaa attatggctc gactggcaaa
    20101 ggaagttcgt caggcttttt ctggagtacg cgatcgccgt cgccgctcat ttatttcact
    20161 ggcgcgaaac tttgatttca aaagtactct gcgcgccaac ctgcaacact ggcacccgca
    20221 acacggcaag ttgtatatcg aatccccccg ctttaacagc cgcataaaac gctatagcga
    20281 acaatggcaa ctggtcctac tggttgatca aagcggatcg atggttgatt cggtgatcca
    20341 ctccgcagtg atggcggcct gtttatggca gttacccggc attcgtaccc atctggtcgc
    20401 ttttgacacc agcgtggttg atctcacggc agacgttgcc gatccggtag agctattaat
    20461 gaaagtgcaa ttaggcggcg ggaccaatat cgccagtgct gtggaatatg gtcggcaact
    20521 tattgaacaa ccagcgaaaa gcgtcattat cctcgtgagc gatttttacg aaggggggtc
    20581 atcatcattg ctgacgcatc aggtgaaaaa gtgtgtccag agcggcatca aagtgctggg
    20641 actggcggcg ctcgatagca gcgcaacacc ttgctatgac cacgatacgg cccaggcgct
    20701 ggttaatgtc ggcgcacaaa tagccgcaat gacaccgggc gagctggctt cctggcttgc
    20761 ggagaatctt cagtcatgaa ttcactacgt ccggaattat tagaactgac gccgcaggct
    20821 ctgacggcgt taagcaatgc cggttttgtt aagcgcagcc ttaaggaact ggaaaatggc
    20881 aacgtcccgg aaatcagtca tgagaacggc gctttaatcg ccaccttcag tgacggtgtc
    20941 cgtacccagc tggcgaacgg ccaggcactg aaagaggctc agtgcacctg cggggccagc
    21001 ggcatgtgcc gtcatcgcgt gatgctggtg ttaagttatc aacgactttg tgccaccgcc
    21061 cagcctacgg aaaaaaaaga agaagagtgg gatccagcaa tctggctgaa agaactggct
    21121 aacctgcccg atgccacccg caaacgcgcg caggcgctgg tcgctaaagg catcaccatt
    21181 gagttgttct gtgcgcctgg cgaaattccc tctgcccgat taccgatgag cgatgtgcgt
    21241 ttttattccc gcagcagcat tcgcttcgca cgctgtgatt gcattgaagg cacactttgc
    21301 gaacatgtcg tactggctgt gcaggccttc gtcgaggcca aaactcagca agcggaattt
    21361 actcatttaa tctggcagat gcgcagtgaa cacgtgacat catctgatga tccgtttgcc
    21421 agcgaagaag gcaaaacgtg tcgtcaatat gttcagcaat taagccaggc attatggctg
    21481 ggcgggataa gtcaaccgcc aatccattac gaggccgctt tcagtcgcgc gcagcaagcg
    21541 gcggaacgct gcaactggcg atgggtgagt gaatcgctac ggcaattgcg cgccagtgtt
    21601 gatgccttcc acgcccgtgc cagccactac catgccggag aatgcttacg tcagcttgcg
    21661 gcattaaaca gtcgattaaa ttgcgtacaa gagatggcgc gacgcgacag tatcggtgaa
    21721 gttcctccca tgccgtggcg cacggtcgtt ggcgctggca ttgccggaga agcaaaactt
    21781 gatcatctgc ggctggtgtc tttaggtatg cgttgctggc aggatattga gcagtatggt
    21841 ttacgcatct ggtttaccga tcccgacaca ggaagtattt tgcatctttc gcgtagttgg
    21901 cagagaagcg aacaggaaaa ctcaccggca gcgacgcgtc ggctgtttag ttttcaggct
    21961 ggcgcactgg caggtgggca aattgtttca caagctgcaa aacgcagtgc cgatggcgag
    22021 ctgctgttag cgacccgtaa ccgcttgagt agtgttgttc cactgtcgcc agacgcctgg
    22081 caaatgttga gcgcgccgtt gcgccagccg ggcattgtgg ctttgcggga atatttacgc
    22141 cagcgtcccc ccgcctgcat acgaccactc aaccaggtcg ataacttatt tattctgccg
    22201 gtagcggagt gtatttcgct cggttgggat agcagccgcc agacactgga tgcgcaggta
    22261 atcagcggcg aaggagaaga taatgtgctg acgttatccc ttccggcatc tgcctgttct
    22321 ccttttgccg ttgaacgcat ggcggcgctt ttgcaacaaa cagacgaccc cgtgagtctg
    22381 gtttctggct ttgtcagttt tgtagagggg caattgacac tggaaccacg ggtgatgatg
    22441 acaaaaaccc gcgcctgggc gctggacgca gaaactgcgc ctgtggcacc gctaccttct
    22501 gccagcgttc tgcctgtgcc gtctaccgct catcagttgc tgatgcgctg ccaggcgtta
    22561 cttattcaac tgctccataa cggctggcgc tatcaggaac agagtgctat tggtgaggca
    22621 gagttgctgg cgaatgacct caccgcggtg ggtttttatc ggctggcaca tgtgttggga
    22681 caatttcgta atacagaaag cgaggcacgg gtagaagcaa tgaataacgg tgttttgctt
    22741 tgcgaacaat tattccccat gcttcagcaa caaggatgaa atagtgcttt ttattaagag
    22801 ttctactcct gttccggact gctcacgcca cagtattagg catatcctat atagcccctg
    22861 gtgagagtca ccagttcctt gattaaataa aatggagttt tacatgaagg ctttcaataa
    22921 gctgttttcc cttgttgttg catctgttct ggttttctct cttgctggct gcggtgacaa
    22981 agaagaatca aagaaattca gcgccaatct gaacggcact gaaattgcca ttacctatgt
    23041 ctacaaaggt gacaaggtgc ttaagcaatc ttctgaaacc aaaattcaat ttgcctccat
    23101 tggtgcaacc accaaagaag atgccgccag gacacttgag ccgttaagcg ccaaatacaa
    23161 aaacatcgcg ggtgttgaag aaaaattaac ctataccgat acctacgcgc aggaaaacgt
    23221 gactattgat atggaaaaag tggattttaa agccctgcag ggtatttcag gaatcaatgt
    23281 ttctgctgaa gatgccaaaa aaggtatcac tatggcgcaa atggaactgg tgatgaaagc
    23341 cgctggtttt aaagaagtga aataatctgt cggcggccat gtttcgcatg gccgccatac
    23401 ccgtcttagc ttttcttcac atgctggcgc gctgccagtc cacgcagaaa ataacgtaaa
    23461 aattgatcgc cgcattcgcg gaagttttta tgatccggtg cacgcatcat cgccgtaatt
    23521 tccggcatcg aaacgcggaa ctgctgttcg gtgaggattg ccagaatgtc atcggtttta
    23581 agcgaaaacg cgatgcgtaa ttttttcagc acgatgttgt tattaatgcg acgttccggc
    23641 tccagtgccg gagcagactc atccttgccg cgtttttcat aaatcaggcc attgaggaat
    23701 gaagacaaaa caatgtccgg acaacgctga aaaccctctt cgtcttcttt acgtagccag
    23761 acggcgatct gttccgcggt ggcttcgaca ttacccagcg ccagaatacg caccaggtca
    23821 ttattattgg ctttcaaaat gtagcgcacg ctgcgcagaa tatcgttact tagcatgagg
    23881 ccttcaggtg ttgatgaggc aaaaagccat tttagcagtc ttttacaggc caatcgcctc
    23941 ttttaagctt ttcagataac ggcggctgac cggcacggtt aagccattac gcaaaatcaa
    24001 ctcggcctgg ccgttatctt ccagacggat ctcctgtaaa tgcgcgaggt taaccagata
    24061 ctgacgatgg cagcgcagta atggtgtacg actttccagg gtacgtaatg tcagttcggt
    24121 aaagccctct ttcccttcgt gactggtaac gtagacaccg ctcatccgac tgctgacaaa
    24181 tgccacatct ttcatttgca gcaaataaat ccgactatgc cccgtacaag ggataaattt
    24241 cagcgcctgt tgattttccg gtaacagcga aacatcctgc ttgctgcgct cctgacgcaa
    24301 tcgcgccagc gttttctcca gtcgcgcttc atcaattggc ttcagcagat aatcaaaggc
    24361 atgttcttca aaggctttaa tggcgtattc gtcaaacgcg gtgagaaaaa caatatacgg
    24421 gcgatgttcc gggtcaagca tccccaccat ttccagacca ctgatgcgcg gcatctggat
    24481 atcgagaaac agcacatccg ggcgcagttt atgcaccgcg ccgatccctt ccacggcgtt
    24541 tgaacactct ccaacgattt caatatcgct ctgctcctgc aaaaatacgc gcaggttctc
    24601 ccgtgcaagc ggttcatcat cgacaattaa gactttaatc atgcctcgtc cctccatggt
    24661 agtcgtaacg ttattcgggt gtaactatca ggctcacagg cgacgcttat cccatagtca
    24721 tcgccaaacc gttcacgtaa acgcttatcc accagattca tccccagccc actggcattg
    24781 gttaccggtt gatacaaacc ggcattgtct tcgatctcca gcatcaaatg ttgcccctca
    24841 cgtcgggcgc tgattgccac tcgccctgta tccagcagtt gtgatgtccc atgtttaatg
    24901 gcgttttcca ctatcggttg cagggtaaac gcgggcaatt gctgctggga taattcttgc
    24961 ggaatagcaa tgttgacctg caaccgcgac tggaagcgcg ccttttcaat ttgcagataa
    25021 gcgttcacat gttcaatttc gtcggcgaga gtaacaaact ccgaaggccg ctttaagttt
    25081 ttgcggaaaa aagtggaaag atactgcacc agctggctgg cctgttcgct gtcgcggcgg
    25141 atcaccgctt taatggtgtt aagcgcatta aacaaaaaat ggggattcac ctgggcgtga
    25201 agcagtttga tctctgactg ggtgagcatc gctttttgcc gctcatattg cccggcgagg
    25261 atctgcgccg aaagcagttg cgcaatcccc tcgcccagcg tgcggttgat tgaactgaat
    25321 aaacggtttt tggcttcata caatttgatg gtacccatca ctcgctgatt ttcaccacgc
    25381 aacggaatga ccagcgtcga ccccagtttg cattgcggat gcaaagagca acggtaaggc
    25441 acttcgttgc catcagcgta gaccacttca ccggtttcaa tcgcttttaa ggtataagtc
    25501 gaagaaatcg gtttgccggg taaatggtgg tcgtcaccaa ttccggtaaa ggccagcaat
    25561 ttctctcgat cggtaatcgc gactgcacca atatccagct cctgatacag cacctgtgcc
    25621 actttcatgc tgttcacttc gttaaacccc tggcgcaaaa tgccttccgt cgaggccgcc
    25681 actttcagcg cagtggcaga aaaagccgaa gtgtattttt caaacatcgc gcgtttatcg
    25741 agcaatatac gcataaacaa cgccgcgccg acggtattgg tgaccatcat tggcgcagca
    25801 atattactca ccagacgcac cgcatcttca taaggtcggg cgatcgccag gatgatcaac
    25861 atttgcacca tttcagcgac gaacgtgacg gcaccggcgg taatggggtt aaagacttta
    25921 tcagtgcgcc cgcgacggat caggatgctg tgaaccaggc cgccgagcaa tccttcaacg
    25981 atggtcgaga tcatgcaact tagcgcggtc atgcccccca tcgaatatcg atgtaacccg
    26041 ccggtcagac caaccagccc accgacgacc ggaccgccga gtaagccgcc cattaccgcg
    26101 cctatcgcac gggtattggc aatagaatcg tcaatgtgca acccaaacca ggtgcccatg
    26161 atgcagaaga tggaaaagac gatgtagcag agaaatttat gcggcagacg aaccgtgacc
    26221 tgcattaacg gtatgaataa tggcgtttta ctcattaacc acgcaatgac taaaaaaacg
    26281 cacatctgct gaagcagcag caacaccaga ttaaaatcgt acatacccgc aaaccacact
    26341 tccctttaaa atgcgtaaca tacattgctt gcgtttaact ttctttgaac tcttgcagaa
    26401 aaatgagaat tcgtgagtac gatcactcaa aatcgcctgg caaaaataaa atcaccctat
    26461 agatgcacaa aaaacgggca aaactacctg gttcgcaaaa ctgcgtctaa agttaaaccg
    26521 ggacctcgcg agcaagggtg agacgatggc gctttacaca attggtgaag tggcgttgct
    26581 ttgtgatatt aaccctgtca cgttacgcgc gtggcagagg cgttacggat tgctgaaacc
    26641 gcaacggaca gacggcggcc atcggctgtt caacgatgcc gatattgacc ggatccgcga
    26701 gatcaaacgc tggatcgaca acggcgtgca ggtcagcaaa gtaaaaatgc tgctcagtaa
    26761 tgaaaatgtt gatgtgcaga acggctggcg cgatcagcaa gaaacattac tgacttacct
    26821 gcaaagcggc aatctgcata gcctgcgaac gtggatcaaa gagcgcggtc aggattaccc
    26881 cgcccagaca ctcaccacac atctgtttat tcctctgcgc cgacggcttc agtgccaaca
    26941 accgactctc cagacgctgc tggcgatcct cgacggcgta ctgatcaact acatctctat
    27001 ttgcctggct tcggcgcgca aaaaacaggg taaagatgca ctggtggttg gctggaatat
    27061 tcaggatacc actcgtctgt ggctggaggg ctggattgcc agtcaacaag gatggcgcat
    27121 tgatgtcctc gcccactcgc tcaatcaact acgccctgaa ctgttcgaag gccgtacatt
    27181 gctggtgtgg tgcggtgata atcgaacctc cgcccaacag cagcaactca ccagttggca
    27241 agaacaaggc catgatattt tcccactcgg catttaatga ttcgttaaca aatgcgcttt
    27301 actgtacaat cctttcgtta acataaggag tgcattatgc gcatagctaa aattggggtc
    27361 atcgccctgt tcctgtttat ggcgttaggc ggaattggtg gcgtcatgct cgcaggttat
    27421 acctttattt tgcgtgctgg ctgaacgcct gcaccagcct ttcaaacagg cggtctgcga
    27481 tgatcgccgc cagtgccacc agtaacgctc cctggatcac atacgcggta ttaaatccgc
    27541 taagtccgat gatgatgggc gtacccagcg tgctggcccc taccgttgag gcgatcgtcg
    27601 ccgtaccaat gttgataatc accgaagttc gcacgccagc cagaatcacc ggagccgcca
    27661 gcggtagctc gaccttacgc agtcgctgac cacgactcat tcccatacct ttcgcaactt
    27721 ctgtcacgct ggcatcaatc gctcccagcc cggcaagtgt cgcctgcagg acgggcagca
    27781 cgccgtaaag gatcaaggcg ataatcgctg gtttcagacc aaagccgatc accggaacgg
    27841 caatcgccag caccgcgacg ggcggaaaag tctgcccaac ggcggcaata gtttccacca
    27901 gtgggcgaaa ttccgcaccc cacgggcgag tgacagcaat tccggcacca gtaccaatga
    27961 tcaccgcaaa caaactcgaa attcccacca gccagaaatg agccagtgcc agagctgcaa
    28021 aactttcttg ctgataaacg ggtcgtggca gttgtgggaa caaggcagca aacagcggct
    28081 ggctataagg tagccagaaa atcagtgcca caaacaaagc aatgagccag aacagcggat
    28141 cgcgcaacat cttcatacgc ttacgcctcc tccagcagat cctgaaaatg cagcgtgccg
    28201 caaggctggc cctgcgtgtt caccaccggc agcacctcgc atccccgcgc gacaaacaga
    28261 gaaagcgcat cgcgtagcgt catcctttct tccagtgcct caccttcagc ccgttcttca
    28321 cggcgcacgt aatctgccac gctacgtaac gaaagcaggc gtacacccag ctcactacga
    28381 ccaaaaaact ggcggacaaa atcattcgcc ggatgagtca gcatcgccag aggattgccc
    28441 tgctgcacga cttcaccgtg atccatcaat accagatgtt ctgccagccg tagcgcctca
    28501 tcaatatcat gagtgaccag cacaatggta cgcccctgca aacggtgaat gcgcgtcatc
    28561 tcttgttgca acgcgccgcg cgttaccggg tccagcgcgc caaaaggttc atccatcagt
    28621 aagacttgcg gatcggcagc cagtgcgcgc gccactccca cacgttgctg ctgaccaccg
    28681 gaaagctgat gcggataacg ctcacgcaaa tttggctcca gccccagtag cgccattaat
    28741 tcgtcgatac gatcgtcgat ccgcgcccgt gaccattttt gcaattgcgg cacggtggcg
    28801 atgttttgtg ccacgctcca gtggggaaac aggccaatag attgaatggc atagcccatc
    28861 cggcggcgca actccagtac tggcagcgag cgaatttctt ctccggcaaa gcggatcacc
    28921 ccgctgtcat gctccaccag gcggttaatc attttcagag tggtggattt accggagcct
    28981 gatgtaccaa tcagcaccga aaaactccct tcctgaaaat tgagattgag atcgttaacg
    29041 gctttttgtg cgccgaacag tttgctgaca tggctaaatt caatcattac gtttcacctt
    29101 cagcagtgcg ataagcaaat cgaacagcgc gtcggtaagc accgccagaa caattaccgg
    29161 gatcaccccc agcaacacta aatcaatggc actgcttagc agcccctgga aaaccagcgc
    29221 accaaaaccg cctgcgccga ttaacgccgc aatcaccgcc atgccaacgg tttgcaccat
    29281 caccacccgc aggctgcgca gaaataccgg taacgccagc ggtaactgaa catgcaggaa
    29341 acgctgcacc ccgctcatcc ccatcgctct ggcgctctcc agcacatcgc gcgggatctg
    29401 gttcaagccg actactacgc cgcgcaccag cggcagcaag gcatagagca ccagcgcaat
    29461 aagtgcgggt gtcattccgg ttcctgctat gccgagcgtt cccagccacg gaaaggccgt
    29521 aaccagcgcg gcaagcggcg caatcagcag gccaaagagc gctaccgaag gcacggtctg
    29581 aatgacattc agcagagaaa aaatcgcccc ctgccgcgcg gtggaaaagt agcaccagat
    29641 gcccaacggc acaccaatca ctaacgcagg cagcaccgca ccaaacagca acgtcagatg
    29701 ttgtgccaga gcgtcgtcaa acacatcctg acggttggcg tattctttca ttaacgagag
    29761 atcgttaagc gtgccggagt acagcaacca cagcggaata atggcaatct gcatatgcaa
    29821 caaccagcgc cacagcggat gcgtggagat tcggcggatg gcatcgctac aggccagcag
    29881 tgccagcgcc gcagccagcc agaaaccact gccgaggctg gtacgtgcca gcgcactgcc
    29941 attttgcgcc agttgtgtcg ccgcctttcc agctccccac accagcaata cgaagacgaa
    30001 ttgcgccaga atgagtgcaa aaatgctgcc ttttttagcg ggaataaaac aggctgtcag
    30061 ccaggcgcaa ccaacgccca ccagcatcca gagagtttgc ggccacagct gccagagatg
    30121 acgcccctca cccgaaacta aacgattagg cgcgtaactg ataaacggca gcgccgctgc
    30181 gattgccgtc agcaacagca gcagcgccag aacaggatta atacgtagat aagtcacggg
    30241 aaattacttc gtccaccctt tttgtttcag gtagtcggca gccacttttt tggcatccag
    30301 tccttccaca gcaatgctgg cattcagttg ctgcaatgtt ttttcatcga ggctggcgaa
    30361 gactggctgt agccactgtg ccatttgtgg atactctttc agcaccgact cacgcaccac
    30421 tggtgcaggc gcgtagatag gttgcacgcc ttgcggatcg cttaaggttt gcagccccag
    30481 cgccgcgacc gggccgtcag tgccgtaagc cattgcggca ttaacgccag aggtttgctg
    30541 ggcagcggct ttgatcgtta ccgccgtgtc gccaccagcc agtgacagca actgatcctg
    30601 accgagctta aagccatagg ctttttcaaa cgcgggtaag gcatcggcgc gttcaataaa
    30661 ctctgccgag gctgccagtt tgaaggtgcc gccctcttgc agataacgac tcaggtcggc
    30721 aagcgaagtg agcttgtttt tctctgccac atcctgacgc acggcgatgg tccaggtgtt
    30781 atttgcaggt gcgggcgtca gccagattaa cttgttttgc tctgcatcga gttttttgac
    30841 tttctcgtaa ccttgctgca cgtttttcca cgctgcatcg ttttcatctt taaagaagaa
    30901 cgccccattg ccggtatatt ccggatagat atccagctcg ccagaagtga tcgcgccgcg
    30961 caccacagga gtcgttccaa gttgcacttt atttaccgta ggaacgccgt gactttccag
    31021 cacctgcaaa atgatattgc cgagcagcgc gccttccgta tcgatttttg aaccaacctt
    31081 aacgggggaa gctgcctgta gcggcaggct cacggctgcc aacaaaacca gtgaacctgc
    31141 ccagaccttt gagagtggca tgatgctttc ctcattcttt tactgttgtt ttcagcgaat
    31201 taagagaaaa gcatagttga taatgacagg gttagcctgt ctgggtggat tcagttgcag
    31261 aatcagataa atacttaaaa ggcatatttt gcccggcgtt tcttgccgga tgcggcgtaa
    31321 acgccttatc cggcctacaa acatcgaaaa ttacaacaac tcaaactcgg ctttcttaac
    31381 gcgtgcggaa tcagtgccga taaagacatt gaacttgcca ggctcggcgt catatttcat
    31441 ctgttgattc cagaacttca gcgcctcaat atcaatcggg aagctgacgg tctgagtttc
    31501 gcccggtttc agagtgattt tctcaaagcc tttcagctgc ttcaccgggc gactcatgga
    31561 agccgtcaca tcctgcaagt acatctgtac taccgtggcc ccttcgcgtt taccggtgtt
    31621 cgtcacctgc acgctggccg tcactttgcc gtcacgcttc atggtcggcg cagaaagttt
    31681 cacatcagag acggtgaaag tggtgtagct cagcccatag ccgaacggat aaagcgcccc
    31741 gttagcttca tcaaaataac gcgaagtgta tttgttcggc ttgtcggcat tatacggacg
    31801 cccggtattc agatggctgt agtacaccgg gatctgcccg acagaacgcg ggaaggacat
    31861 cggcagcttg ccggacgggt tataatcgcc aaacaataca tcggcaattg cattaccgcc
    31921 ttcagtcccc gcaaaccagg tttccagaat cgcatcagcc tgctgatctt ctttcaccag
    31981 cgccagcgga cgcccattca tcagcaccag caccagcggt ttaccggtgg ctttcagcgc
    32041 cgcaatcaag tcacgttggc tttgcggaat agtgatatcg gtacgactgg aagcttcgtg
    32101 cgccatcccc tgagcttcac cgaccacagc caccaccaca tcagattgtt tcgcggtttg
    32161 caccgcttca tcaatcatct cttgcggcga acgcggatcg actttgaccg cttcttcata
    32221 ctgattcagg aaatcgataa tgcctttgtc actggtaacg ttcgcccctt tggcatacag
    32281 cactttaccg ttttcaccga cggcgttttt aatcccggtt agcacagtaa cagattgatc
    32341 ggcgacacct gctgccgacc agcttcccat cacgtcacgc ttgctgtctg ccagcgggcc
    32401 aaccaccgca atggttgcag attttttcag cggcagcgtt tcgagacggt ttttcagcaa
    32461 caccaggctt tcgcgcgcca cttcacgcgc ttctttgcgg tgcaggcggc tttcggcatt
    32521 ggtatccacc gggtcagact ctttcggccc caaatggctg tatggatcgt taaacaatcc
    32581 catatcatat ttaacgttca gtacatggcg ggcagcatcg tccagctctt ccatcgtcac
    32641 tttgccggat ttgatcaacc caggcagata cttcgagtaa tactcgtcgc tcatgctcat
    32701 gttgattccg gacttcagcg ccacgcgtac cgcatcctct gggtctgccg ccgtgccatg
    32761 tttaatcagt tctttgattg cgccgtgatc ggaaacggtg atgcctttaa agccccactg
    32821 gtcgcgcaga acatctttca gcagccagga gtcggaggtg gctggcgtgc cgttcagcga
    32881 gttcagcgcc accatcaccg caccgctgcc tgcatccagc cccgctttgt acggcggcat
    32941 atagtcgtta aacaggcgct gcggactcat atcgacggtg ttgtactctt taccgccttc
    33001 taccgcgccg tatgcggcaa agtgtttgac gctggtcatc accgagtagc gatctgccgg
    33061 gcttttaccc tgcatcgctt ccaccatggt tttacccatt attgaggtga gatacgtatc
    33121 ttcgccaaaa ccttcggaag cacgtcccca gcgcggatcg cgcgagacat cgaccatcgg
    33181 tgcccaggtc atattcaggc catcatctgc cgcttcataa gcagagacac gcccgactgt
    33241 tttcaccgca tcgaggttaa aagacgaggc cagaccgaga ctaatcggga acaccgtgcg
    33301 ctgaccgtgc agcacgtcgt aagcaaagaa aagaggaatt ttcaggcggc ttaattccat
    33361 cacctgatcc tgcatggcgc ggatatcctg acgggttacg gtgttgaaaa tcgccccaac
    33421 ctgaccgtct ttgatcatct cgcggatcgc ctctttcggg ttatccgggc cgacgctgat
    33481 taagcgcagc tgaccaattt tctcatcaac tgtcattttc ttaagcagtt cggtgacgaa
    33541 cgcatcccgc gcttcgggcg ttaatggatg gttgccgaat aaatcatccg ccagtgctgg
    33601 ctgcagggcc agactcaccg cgattcctac tgaacatagc catttcatat ggatttttct
    33661 tcctttgttg cccgacgtgg cagcgaaaat ggtgcaaaaa ccgtagtttg ccataagcat
    33721 gatggagaga gaaaaagaat gctcagttta ttgtctgaat tttcaaaata ttcactcgct
    33781 gaattgtcat acaaggcgct attctagttt gtgatatttt ttcgccacca caaggagtgg
    33841 aaaatgtctt ccatgacaac aactgataat aaagcctttt tgaatgaact ttcccgtctg
    33901 gtcggtcatt cacacctgct caccgatccc gcaaaaacgg cccgctatcg caagggcttc
    33961 cgttctggtc agggcgacgc gctggctgtc gttttccctg gctcactact ggaattgtgg
    34021 cgggtgctga aagcctgcgt caccgctgac aaaattattc tgatgcaggc ggccaataca
    34081 ggcctgaccg aaggatcgac gccaaacggt aacgattatg atcgcgatat cgtgatcatc
    34141 agcaccctgc gtctcgacaa gctgcacgta ctcggtaagg gcgaacaggt gctggcctat
    34201 ccgggcacca cgctctattc actggaaaaa gccctcaaac cgctgggacg cgaaccgcac
    34261 tcagtgattg gatcatcgtg tataggcgca tcggtcatcg gcggtatttg taacaactcc
    34321 ggcggctcgc tggtgcaacg tggcccggcg tataccgaaa tgtcgttatt cgcgcgtata
    34381 aatgaagatg gcaaactgac gctggtgaac catctgggga ttgatctggg cgaaacgccg
    34441 gagcagatcc ttagcaagct ggatgacgat cgcatcaaag atgacgatgt gcgccacgat
    34501 ggtcgtcacg cccacgatta tgactatgtc caccgcgttc gtgatattga agccgacacg
    34561 cccgcacgtt ataacgctga tccggatcgg ttatttgaat cttctggttg cgcagggaag
    34621 ctggccgtct ttgcagtacg tcttgatacc ttcgaagcgg aaaaaaatca gcaggtgttt
    34681 tatatcggca ccaaccagcc ggaagtgctg accgaaatcc gccgtcatat tctggctaat
    34741 ttcgaaaatc tgccggttgc cggggaatat atgcaccggg atatctacga tattgcggaa
    34801 aaatacggca aagacacctt cctgatgatt gataagttag gcaccgacaa gatgccgttc
    34861 ttctttaatc tcaagggacg caccgatgcg atgctggaga aagtgaaatt cttccgtccg
    34921 cattttaccg accgtgcaat gcaaaaattc ggtcacctgt tccccagcca tttaccgccg
    34981 cgcatgaaaa actggcgcga taaatacgag catcatctgc tgttaaaaat ggcgggcgat
    35041 ggcgtcggtg aagccaaatc gtggctggtg gattatttca aacaggccga gggcgatttc
    35101 tttgtctgta cgccggagga aggcagcaaa gcgtttttac accgtttcgc cgctgcgggc
    35161 gcagcaattc gttatcaggc tgtgcattcc gatgaagtcg aagacattct ggcgctggat
    35221 atcgctctgc ggcgtaacga caccgaatgg tatgagcatt taccgccgga gatcgacagc
    35281 cagctggtgc acaagctcta ttacggccat tttatgtgct atgtcttcca tcaggattac
    35341 atcgtgaaaa aaggcgtgga tgtgcatgcg ttgaaagaac agatgctgga actgcttcag
    35401 cagcgtggcg cgcaataccc tgccgaacat aacgtcggtc atttgtataa agcaccggag
    35461 acgttgcaga agttttatcg cgagaacgat ccgaccaaca gtatgaatcc ggggatcggt
    35521 aaaaccagta agcggaaaaa ctggcaggaa gtggagtaat aattacggat ggcagagtat
    35581 cgccatccgt cattcattta atcgttctgt gccgtctgcc ccgccgccgc catttgggcg
    35641 gctttttgtt ttttatagct caacgctgct gccggaacag gcatcacttt accggtttca
    35701 atccaggtac gcaggcggct ggcatcggca aaatgggtat atttgccaaa cgcgtccatc
    35761 actaccagcg ccaccggttt attattgata accgtgcgca tcaccagaca atggcccgcc
    35821 gcattggtaa aaccggtttt ggttaactga atattccagt tatcacgata caccagatgg
    35881 ttagtattgc ggaacggcag cgtatacgtc gggttagaga aggttgccat atcttcccgg
    35941 gtagtactta actgcccgat caacggatat tgtttgctgg caatgagtag tttggttaag
    36001 tcacgggcgg ttgaaacgtt atgcaccgac aatccggttg gttcaacaaa gcgcgtgttg
    36061 ttcattccga gcgatttcgc tttcgcattc atcgccttaa taaaggcttt gtaaccaccg
    36121 ggataatggt gcgcaaggct tgccgccgcg cggttttctg aagacatcag cgccagcaac
    36181 agcatatctt tacggctgat ttcgctgttc agtcgtacgc gcgaatagac ccctttcatc
    36241 tccggcgtct ggctgatatc cacttttagt ttttcatcca gcggcagtcg tgcatccagc
    36301 acaaccatcg cggtcattaa tttgctgata gacgcaatcg gacgcaccag atccgggtgg
    36361 ttcgaataga tcactttgtt ggtattcaga tcaacaatca tcgcgctacc ggaggcaatt
    36421 tccggttgtg acgcggtggt agcggctgcc gttttcgcaa cggcctgcgg tgcaaaaggc
    36481 acagccagca tcagggccag gctaaataaa gaaactcgaa atttcggcat gatgagcatt
    36541 cagatagtgg ttcacgcgca cgggttgcgc accgccggag taaggattta ctgaggctag
    36601 cgacgccatc ataacgagca aaaagtgcga tcgtcaaagg agaatcgtga ggaaatgctg
    36661 cattgctgac atttacgcca gcaatgcagc gcaaaagaac tttctagaac aaacgataac
    36721 cgtagcccca tagtataacg gtaagggcga gcagcacttc cagcaccagc acgcctatcg
    36781 ccagtgtcga actggagaag ctaagtcctt cctctttgtt gatattcagg aagctcggaa
    36841 taccgagata cagcaggtag ccggtgtaaa acagcgccac cgtgccgacc agcgcacaca
    36901 accagaccag cgggtaaagc gccaccagac cgcttaaaaa cagcggagtt gcaacgtagc
    36961 ccgcgaagac catgcagtgc gcaagtgacg gacgctgcgg ataattacgc gccatccacc
    37021 agatgacccg ccccatcacc gcaaccccag ccagcataac gccgtaaaac aagacagcca
    37081 gcgccagtcc ggtaaaccag gataacttca ggatagtgcc atcgccaaaa ttccagccaa
    37141 tctgtgtagt gccaatgaag gcgcaaatca ccggaatcgc cgccatcagc aaaacgtggt
    37201 gggtgtagtg atgagaaatc gtttcgtttt cgcgattaat cacctgcatt tcacgatcgg
    37261 gatgggaaaa cagtccccag acatggctca taccgccccc ttgttgtgag ttcatgaacc
    37321 tgacagttca agtataagtc agcttgtgat tattttttgt tcactcatgt aatttgcacc
    37381 gtctgatgta cgtccttttt cagcgtgaat gattcacagg gtgtatgctt acaggcaagc
    37441 aaagggagac agactgtcct atggatctca atacactcat ctcacaatat ggttatgccg
    37501 cgctggtgat cggtagcctg gcggaaggtg aaaccgtgac tttgctggga ggcgttgcgg
    37561 cacatcaggg gctattaaag ttcccgctgg tggtactttc tgtggcgctt ggcggcatga
    37621 ttggcgacca ggtgctttat ctgtgcgggc ggcggtttgg cggcaagcta ttacgccgtt
    37681 tctcgaaaca tcaggataaa attgagcggg cgcagaaact gatccaacgc catccgtatc
    37741 tgtttgtcat tggtacgcgt tttatgtatg gctttcgggt cattggcccg acgctgattg
    37801 gtgccagcca gctgccgccg aaaatctttc tgccactgaa tatcctcggc gcatttgcct
    37861 gggcgttgat ttttaccact atcggttacg ctggtggtca ggtgattgcg ccgtggttgc
    37921 ataatctcga ccagcatttg aagcactggg tctggttgat tctggtcgtg gttctggtgg
    37981 taggcgtgcg ctggtggctg aaacgacgcg ggaagaaaaa gccggataat caggcgtaaa
    38041 accattgcct aggataaggc gttcgcgccg catccgacat ccggtgcacc atgcctgatg
    38101 cgacgcttgt gcgtcttatc atgcctaccc aaatattacc cattgaaata accacgcacc
    38161 tcactgcgct attctgggtt gaactgcgga ttcgccagca taaagccgcc atccactatc
    38221 aacgactgcc cagtggtgta atttgcgccc tccgaacaaa gccacaccac caggctggca
    38281 atctcatgcg ttgcgccaaa acgccgcaag ggaatcgaag gctccgcgcc gggcttcacg
    38341 tcgccatcat ccatgccgtt cattggcgtg gcgatcgccc caggtgcaac cgcattcacc
    38401 aaaatcttat gcctgaccag ctccagcgcc atcgctttgg ttaacccgcc gagcgcatgt
    38461 ttagcggctg tgtaggcgct ggcatccggc aacggcgtat gttcatgcac cgacgtaatg
    38521 ttgatgatgc gaccaccctg cccttgtttc accatctggc gggcagcaat ttgcgagcat
    38581 aaaaatgcac catcgacatc aacggtaaaa atcttgcgcc actcatcgaa agccatatca
    38641 agaaacggcg ctttggtcat tgcgcccgca ttattcacca gcacatcaat acgccccagc
    38701 cgttgaatga gtttctccag cgccagtgcc ccttctggta gattgccgag atccagctgc
    38761 acgatctccg cacgtacgcc gtggctaact acctcacgcg cggtatcttt tgccccttct
    38821 tcatctgagt gccaggtaat gccaatatca aacccctgct gcgccagtaa taacgcgcac
    38881 tctttgccga tccccgaatc ggaggcggta ataatcgcga cctgtgccat cgagttctcc
    38941 acttaacgct gaataaacgt taagtataga aggcgcatat catcagcgtt tgtaaccccc
    39001 gcccaacgca ccagtgagtt gaatggaggc atccagccac tgcccttgca ataacaggcc
    39061 attggcccgc tcacgcagcg cggggattct ggcttcgctg acgcgggaac ccgcaatgat
    39121 gcccgcgtta aagcgcgcct gcgcaagacc tactacacgc aaggcatcgc gctcaatttg
    39181 cgcctgatgc tggtttttct ccgccagtgt ctgaacctga ctggctgccc gcgccacgtc
    39241 attcaccgct tcaaccaccg ctttgttgta gctggcgata gacaagttgc tttcggcttt
    39301 tgcgatatcg aggttggcgt taagacgacc actatcgaaa atgggtagcg tcaggcctgc
    39361 cgtaacgccc atttgctgcg cggaatgacg gaacagatcg cttaagtgca acgcatcctg
    39421 ttgcaggaag gccatcaggt tgatgtcagg ataaaatgcc gcttttgccg catcaatagt
    39481 gcttaacgat gactcaacgt accagtgcgc cgcctgcaaa tctgcccgcc gggccagtaa
    39541 ggagtacccc agttcatcag gaagctgact tgccactttc ggcaacgcga ccggattaag
    39601 cttcaatgcc tttgtctggt gatttgtaag tgcgcttaac cgtgcctcaa taattttcat
    39661 tttccccgcg acatcgttga gctgctgccg ggttttgctg gcattaatat cggtttccac
    39721 accttcaact gaagaagtaa tcccgttctg atatagctgg cgatcggtgg cgataatggt
    39781 gttctgctct ttttcgattt gctgtaagac agtgtttaac gccgcctggg tttgccactc
    39841 ccagtacagg cgggctacgc tgccagccag caattggcgg gtttgctcgc gttccgccgc
    39901 tcgtgcttta accgtaccca ggcgagcagt tacctctgcc cgattctttc cccagatatc
    39961 gagatgccag cccgccgtta agccaaaagt accgttggtg taccacggac cggtcgtacc
    40021 tgcggcagga tcgttcagag caaacggccc cattaaccct tctgcagaca ttttttgccg
    40081 ctccatatcc gcagaaaagt cgatctgcgg accatcctga gtagcaactg ccttcgcctg
    40141 ggcttcagcc agttgaatgc gctgttcagc cacctgcata tccggtgcgt tctgtagtgc
    40201 attgttaatt aaggaagtga gttgattatc gtgatactcc agccaccatt ggctgtctgg
    40261 ccaaccattt ttcagcgccg tgggtaatgc ggtgtcaact tgtgcagcgg gcgtttgctg
    40321 gcttaacgcc tggcgggttt catgcatagg tgcacacccg gccagcatca gtaacagcgg
    40381 aaaacaggcg atggcgggat aaaaggaatc acgattcatg ggggaataat caggtaagaa
    40441 aaggtgcgcg gagattaccg tgtgttgcga tatatttttt agtttcgcgt ggcaatacat
    40501 cagtagcaat aaaacgacat atccagaaaa atatacacta agtgaatgat atcttccgat
    40561 ttatcttaat cgtttatgga tagcggcaaa gggcttcgtt ttttcctata cttattcagc
    40621 actcacaaat aaaggaacgc caatgaaaat tatactctgg gctgtattga ttattttcct
    40681 gattgggcta ctggtggtga ctggcgtatt taagatgata ttttaaaaat cagatatggc
    40741 atataagttg tcaggtcagg aactagatat tttgtgtact tgatttgcaa acagctccgg
    40801 tgttggtggc gtcaaaatcg ctgaagcgtt ccccgaaggc cggggcagcc cacatggatg
    40861 tgggctgagg gcgcgtctta caaggacgtt acctcgcgcc cgacccggta gccgaagggg
    40921 ataagctgaa ggtaccgcgc agcggcgatt ttgttcgcca gagcccgggg gtgcaggggg
    40981 aggaggcgat tgtcctcccc ctgcgcgctc cttgcgccag tggcaatatg tggcttagct
    41041 catgaaagga gcgcaacaag atgatgaagc tgaataagcg attcattgtc tcagataagc
    41101 tgcgattcca ctattatcgc agcttatcga tatcaatggc ctgaatagcc cttgcaatat
    41161 caggggaatt attcaacacc cgaacatgct gaaataattc cgttgcttca tcgtattctt
    41221 tacgcaaata actcaaccac tgtttaatcc gcgcaacgtg atataacccg gtatcgccct
    41281 gcttttccag acgggtatat ttttgcagca aagcaaccac ctccggccac ggcattcgcg
    41341 gttcgttata tttcaccaca cggctcaggt tgggaatatt gagcgccccg cgaccaatca
    41401 tcactgcgtc gcagccgctg atcgccatgc attgttgcgc actctgccag tcccagattt
    41461 caccgttggc aatcaccgga atattaagcc gctggcgaat ctcgccaatc gcctgccagt
    41521 caatatgttc cgcgcggtaa ccctgctctt ttgtccgccc atgtactacc agctccgtag
    41581 caccagcctg ttgaaccgca tcggcgattt caaatttctt ctcaccgctg tcccagccca
    41641 gacgcacttt tacgctgaca ggcaaatgcg ccggtacagc ttcgcgcatc gcttttgcac
    41701 cctggtagat gagttcagga tctttcagta acgttgcccc accaccgcta ccgttaaccg
    41761 ttttcgacgg gcagccgcag ttaagatcca cgccccagga acctaactcc accgcacggg
    41821 cggcgttctc tgccagccac tgtgggaact gccctaacaa ctgcacgcga accagcgtac
    41881 cggatggtgt ccggctggca ttttgtagct cagggcaaat gcgatgaaag acttttactg
    41941 gcagcagttg atccaccacg cggacaaact cggtgatgca cagatcgtag tcgttaactt
    42001 cggtcagtaa ttcccgcacc agagagtcaa gtacaccctc catcggagcc agtaacacac
    42061 gcatatcatc acccgcaaaa aaatgaggcg ctatgttagc gcctccggtc aacggattaa
    42121 aggtctgcaa agagggattg ctgcaaactg caatccctct ctatgcttga tgtatgcctg
    42181 agttcgctgc gcattgcgta ataccgggga gcgaaaaaat aagcgctgat ttcttaatgt
    42241 gatcggtagc acgttttacg aattaattgt atgatgaatc catctcatct ggggtgttga
    42301 ttatgagtaa gacactgaac attatctggc aatatttacg tgcttttgtc ctgatttatg
    42361 cctgcctgta tgcaggcatt ttcattgctt ccctgctacc ggtaaccatt ccgggcagca
    42421 tcatcgggat gctgatcctg tttgtcctgc tggccttgca aattcttccg gcgaaatggg
    42481 tcaatccggg gtgctacgta ctgattcgct atatggcgct attgtttgtg ccgattggtg
    42541 taggcgtcat gcaatatttt gatttgctcc gcgcacagtt tggtccggta gtggtttcct
    42601 gtgcagtcag tacgctggtg gtttttctgg tggtgagctg gagttcacaa ctggtgcatg
    42661 gtgaacgtaa agtcgtaggt cagaaaggat cagaagaatg atggcgaata tctggtggtc
    42721 attaccgctg acgttgattg tcttttttgc cgcccgcaaa ctggcggcac ggtataagtt
    42781 tcccctgctt aacccgttgc tggtagcaat ggtggtgatc attccttttt taatgctgac
    42841 cggcatctct tacgacagct actttaaagg tagcgaagtg ctaaacgatc tgctgcaacc
    42901 ggcggtcgtc gcactggcct atcctttata tgagcagcta caccagatcc gcgcgcgctg
    42961 gaaatcgatc atcaccatct gttttatcgg cagcgtggtt gcgatggtga cggggacttc
    43021 tgtggcattg ttgatgggcg cttcaccgga aatcgccgcg tcaatcctgc cgaaatcagt
    43081 caccacgcct attgcaatgg cagttggcgg cagtattggc ggtattccgg caatcagcgc
    43141 agtttgcgtg attttcgtcg gcatcctcgg cgctgtgttt ggtcatacat tgcttaatgc
    43201 gatgcgtatt cgtaccaaag ctgcgcgcgg tctggcaatg gggacagcct cgcacgccct
    43261 cggtacggcg cgctgcgccg agctggatta tcaggaaggt gcatttagtt cgctggcgct
    43321 ggtgttatgc gggattatta cttcgctgat cgcaccgttc cttttcccga ttattctggc
    43381 agtaatgggc taaaatttgc gatgcgtcgc gcatttttga tgtaagtttc acgcgttgca
    43441 taattaatga gattcagatc acatataaag ccatagcggg ttcgtaaact gttatcccat
    43501 tacatgatta tgaggcaacg ccatgcatcc acgttttcaa accgcttttg cccaacttgc
    43561 ggataacttg caatctgcac tggaacctat tctggcagac aagtacttcc ccgctttgtt
    43621 gaccggggag caagtctcat cgctgaagag cgcaacgggg ctggacgaag acgcgctggc
    43681 attcgcacta cttccgctgg cggcggcctg tgcgcgtacg ccattgtcga attttaatgt
    43741 tggcgcaatt gcgcgcggtg tgagcggaac ctggtatttc ggtgccaata tggaatttat
    43801 tggtgcgaca atgcagcaaa ccgttcatgc cgaacaaagc gcgatcagcc acgcctggct
    43861 gagtggtgaa aaagcgcttg cagccatcac cgttaactac acgccttgtg gtcactgccg
    43921 tcagtttatg aatgaactga acagcggtct ggatctgcgt attcatcttc cgggacgcga
    43981 ggcacacgcg ctgcgtgact atctaccgga tgcctttggg ccgaaagatc tggagattaa
    44041 aacgctgctg atggacgagc aggatcacgg ctatgcgctg actggtgatg cgctttctca
    44101 ggcggcgatt gcggcggcaa accgttcgca catgccttac agtaagtcgc caagcggtgt
    44161 cgcgctggaa tgtaaagacg gtcgtatttt cagcggcagc tacgctgaaa acgccgcatt
    44221 caacccgact ctgccgccgt tgcagggggc gttaattctg ttgaatctca agggttatga
    44281 ttacccggat atccagcgcg cggttctggc agaaaaagcc gatgcgccgt tgattcagtg
    44341 ggatgccacc tccgcaacgc tgaaagctct cggctgtcac aatatcgacc gcgtgcttct
    44401 cgcttaagcc tggtgccgga tgcggcgtga acgccttgtc cggcttgcca gccctttcct
    44461 ggtgtcgaaa atcccggcaa acagtttgcc gtttcttgcg caaaaccagc gggtaaagta
    44521 gcctgatgga aattttcctt agatcgagtc tcctgcatgt taaagcgcgt gttcctcagc
    44581 ctgttagtcc tgatcggctt gctgctgttg actgtgctcg gcctcgatcg ctggatgagc
    44641 tggaaaaccg cgccttatat ctacgacgaa ttgcaggatc tcccctaccg ccaggtcggt
    44701 gtggtgctcg gcacagcaaa atattatcgg actggcgtaa ttaatcagta ttatcgctac
    44761 cgcattcaag gagcgattaa tgcctataac agcggtaagg taaattatct attactgagc
    44821 ggcgataacg cattgcaaag ttataatgag ccgatgacca tgcgcaaaga tttaatcgca
    44881 gccggtgtcg acccatcaga tattgttctc gattacgcag gctttcgtac gctggattcc
    44941 atcgtacgta cacgcaaagt tttcgatact aatgatttca ttattatcac ccaacgtttc
    45001 cactgtgagc gggcattatt tattgcgctg catatgggga ttcaggctca gtgttatgcc
    45061 gtaccgtcac cgaaagatat gctgtcagta cgtattcgcg aatttgccgc ccgtttcggt
    45121 gcgctggctg acctttatat ttttaaacgt gaaccgcgtt ttttagggcc gctggtccct
    45181 attccggcaa tgcatcaagt gccggaagat gcgcaggggt atcccgctgt cacacccgaa
    45241 cagttacttg aattacaaaa gaaacaagga aagtagttat ggatgtacag cagttttttg
    45301 tcgttgccgt ttttttcctt atcccgatat tttgtttccg cgaagcatgg aaaggctggc
    45361 gcgcaggcgc gattgataaa cgggttaaaa atgcaccgga accggtgtat gtctggcgag
    45421 cgaaaaatcc cggactcttc ttcgcttata tggtggcata tatcggcttc ggaattttat
    45481 ctatcggcat gattgtttat cttattttct atcgttaata ttttctcttt tctgttaatt
    45541 attgagaata attattactt cactcaataa gctgcggata taacattctg aaccgcagct
    45601 atttgtgaat cctttcacag tttaaatttc cccacgcgca tagccttaat atcagcacgc
    45661 aatatttatt tagcgttcgc cttaattact catagcatta aggaagatca catgccgcaa
    45721 caaaattatc tggatgaact cactccggct tttacgcctt tactggcgat taaagaagcc
    45781 tctcgctgtt tattatgtca tgacgctccc tgtagtcagg cttgcccggc acagaccgat
    45841 ccggggaaat ttattcgctc aatctacttt cgtaatttta aaggcgctgc cgagacaatt
    45901 cgcgaaaata atgccctcgg tgccgtttgt gccagagtgt gcccgacgga gaaattatgc
    45961 caaagcggtt gtacacgtgc cggtgttgat gctcccattg atatcggtcg cttacagcgt
    46021 tttgttactg attttgaaca acaaactggg atggaaattt atcagcccgg tactaaaacg
    46081 ctcggcaaag tcgccattat tggcgcaggt cctgccggat tgcaggccag tgtgacgctg
    46141 acaaaccagg gttatgacgt cacgatctat gagaaagaag cacaacccgg tggctggttg
    46201 cgtaacggca ttccgcaatt ccggttaccg caatcggtgc tggatgcaga aatcgcccgt
    46261 atagaaaaaa tgggcgtgac cattaagtgc aataacgaaa tcggtaaaac actcaccctg
    46321 gagcagctga aagcggaaaa ccgcgcggta ctggtcaccg tagggttatc gagcggttcc
    46381 gggttatcgc tgtttgagca tagcgacgtt gagattgccg ttgacttcct gcaacgtgca
    46441 cgacaggcgc aaggcgatat cagcattcaa caaagcgcat taattatcgg cggcggtgat
    46501 gtcgcgatgg acgtagccag cacgctgaaa gttctcggct gtcaggcggt aacctgcgta
    46561 gcgcgtgaag agttagatga gtttccggca agcgaaaaag agtttaccag cgccagagag
    46621 ctgggcgttt cgatcatcga tggatttaca ccagtagccg tggaaggcaa taaagtcacc
    46681 tttaagcatg ttcgtttacc gggtgaacta acgatagcgg cggacaaaat tattctcgct
    46741 gtaggtcaac atgccgaact tgctgctttt tccgcactgg aaccgcaacg taacaccatc
    46801 gaaacgcaac attaccagac ccgcgacccg caagtctttg ctgctggcga tattgttgag
    46861 ggtgacaaaa ccgtggtcta tgcagtgaaa accgggaaag aagccgccgg ggcgattcat
    46921 cactatttag agggagcttg ctcatgttaa cgaaagatct ttcgattact ttttgcggcg
    46981 tgaagtttcc caacccgttc tgcctttctt cttcgccggt aggcaactgc tatgagatgt
    47041 gcgccaaagc ctacgacaca ggttggggcg gcgtggtgtt taaaacgatc ggttttttta
    47101 tcgccaacga agtctcgccg cgttttgatc atctggtgaa agaagatacc ggttttatcg
    47161 gcttcaaaaa tatggagcag attgctgaac atccgttgga agagaatctg gccgccctgc
    47221 gtcggctgaa agaagattac ccggacaaag tattgatcgc ttcaatcatg ggcgaaaatg
    47281 agcagcaatg ggaagagctg gcgcgtctgg tgcaagaagc tggcgcggat atgatcgagt
    47341 gtaacttctc ctgtccgcaa atgacttctc atgcgatggg tagcgatgtc gggcaaagcc
    47401 cggagctggt agaaaaatat tgtcgggcag taaaacgtgg ttccacgctg ccaatgctgg
    47461 cgaagatgac gccgaatatt ggtgatatgt gcgaagtggc gctggcggcg aagcgcggcg
    47521 gcgcagatgg cattgcggcg attaacaccg ttaaatccat caccaatatc gatcttaatc
    47581 agaaaattgg tatgccgatc gttaacggta aatcgagtat ttccggatat tccggtaaag
    47641 cggtaaaacc gatcgcccta cgctttattc agcaaatgcg cacccatcca gaactgcgcg
    47701 atttcccgat cagcggtatc ggcggcattg aaacctggga agatgcggcg gagtttttat
    47761 tgctcggttc agcgacgttg caggtgacca ccggcattat gcagtacggg tatcggatag
    47821 tggaagatat ggcaagcggg ttgtcgcatt atctcgccga tcaagggttt gattcgttgc
    47881 aggagatggt aggtctggcg aatcacaata ttgtcccggc ggaagattta gaccgcagtt
    47941 atattgtcta tccccatatc aatcttgata aatgtgttgg ctgtggacgc tgttatattt
    48001 cctgttacga cggcggtcac caggcgatgg aatggagcga gaaaacccgc acaccgcatt
    48061 gtaataccga gaaatgcgtg ggttgtctgc tttgtggtca cgtctgcccg gtaggttgta
    48121 ttgatcttgg ggaagtgaag tttaagaaag gcgagaaaga acacccggta acgttgtaaa
    48181 accagcgacg catccggcat ttagttcctg tcgccagatg cggcgtgaat gccttacccg
    48241 gcatacaaaa caatataaat cagtatgttg tgctcattgt aggccggata aaacgcgcca
    48301 gcgttgcatc cggcatttgg ctcctgtcgc cggatgcggc gtaaacgcct tatccggcct
    48361 acaaaaccac acagatcatg atgttatgtg cgtttatgaa cgaatgcgga ccacattcac
    48421 atcatttctt acgcgcgtat ttcagtgaat ccagcgccac ggcaaagata ataattgccc
    48481 ctttgatgat gtactgccag tacgggttta cgccgatgta cgtcaggcca tagttgatga
    48541 cggtaaaaat aatcaccccg gtcaccacgc caatcaccgt ccctacaccg ccgctgaacg
    48601 atacgccgcc taccacgcac gctgcgatag catccagctc atacatgaag ccgaggttgt
    48661 tggtggcaga gccgatacgt ccggcttcta acatcccgcc gaaggcatag aacacaccag
    48721 acaacgcgta gatcatcagc aggttcaggc cgacgttgac accagatact ttcgccgctt
    48781 ccgggttacc gccaatggca aaaatgttct tgccgaagcg ggttttgttc cataacaccc
    48841 agacaaacac caccgcaatc aacgcataga aggtgatgta agagagacgg aaactcccca
    48901 gcgcaataaa gccttgggca aaagtggaga aaccactgtc aaaaccggaa attggcgacg
    48961 ccccgacaaa gtcgtaatag agcgagttaa tgccgtagac gataatcatc gtaccgagcg
    49021 tggtaatgaa cggcgtcacg ttgagatagg cgataatcaa gccgttgatc aaaccgatca
    49081 ccgcaccaat ggcacagaca atcagaataa ccagcgcaat cggcatcgtc gccatttccg
    49141 ggaacacttt gttggcgtta tccatggact gcaataacgt cgctgctact actgccgcca
    49201 gccccacctg gcgacctgcg gaaaggtcag tcccctgggt gacaattaac cctgccacac
    49261 caagcgcgat aataatacgc accgatgact gggtgagaat attacttaag ttcaacagac
    49321 ttaaaaatgt tgggtcctgg aaaataataa tcgccagcaa aactaaaaga acgacgtaaa
    49381 taccgccctc tttcaggtaa gtaagaaaac ttttcttatt taacgcactc atgggaagcc
    49441 cctaatctta aaggtgcaaa gacgcaagac gcagaatttc gctttgcgtt gttgtttttg
    49501 tatcgacaat tccggaaacg agaccattgc tcatgaccag aatacggtct gttatcccta
    49561 acaactctgg catttcggag gagataataa taatcccctt gcctttcttc gccagttcgg
    49621 caattaactg ataaatctca aacttagccc caacatcaat accgcgcgtc ggttcatcga
    49681 gcattaatat ttctggttgc gttaacagcc agcgaccaat aatcactttt tgctgattac
    49741 caccggagag cgaaccaatt tgcgtccgat gccccggtgt ttttacccgc atcgaatcaa
    49801 tcacccactg ggtatcgctt ttcatccgcg agttatccag taaaccaact ttatttttat
    49861 agttgcggat attggaaatt aacgagttaa agccaatatc cagataggca taaattcccg
    49921 ttgagcggcg ctcttcagtt accagtgcaa atccgtggtt tatggcttcg ttggcattat
    49981 ggttattgat ctttttgccg tgcaacgtaa tggtgccagc cgatttctcg cgaataccaa
    50041 ataacgtctc aacaatatcg gtacgtttcg ctcccaccag accggcaata ccgaggatct
    50101 cccctttatg cagatcaaac gagacatcgc gaatcgacgg ctggcgcagc gacgtcaggt
    50161 tacgcacttc cagaatcact tcgcccggct tgttttcttt gtcagggaaa cgctggttaa
    50221 gagaacgccc aaccatcatg gcgatgattt tgtccatcgt cagtcctgcc agcggttcgg
    50281 tagcgatcca ctgaccgtcg cgcaatacgg taacttcatc acataactgg aagatttctt
    50341 ccattttatg cgagatataa acaataccgc agccgcgctc ttttaattta cgaataatag
    50401 tgaacagatg attgacctct ttttcggtta acgaagaagt cggttcatcc ataatcacaa
    50461 ttttcgcgtt ataggaaaac gctttggcga tttcgatcat ctgcatttgc gaaacagata
    50521 atgtaccgac gcgcgcacgc ggatcgatat caatatccag ttcatcaaaa atcgctttgg
    50581 tttcgcggta cattttgtcc tgatcgacaa acatgccttt ggtgggatat cgccccagcc
    50641 acatgttgtc catcaccgaa cgttgtaata ccaggtttaa ctcctgatgt accatcgaaa
    50701 taccattttc cagtgcttct ttggcggaat ggaaatcgat ctctttaccc tggaataaaa
    50761 tggtgccgga gtctttttga taaataccaa acaggcattt taataatgtc gattttcctg
    50821 caccgttttc ccccattaat gcatggatag aatgtggccg gacttttaag ttaacgttat
    50881 caagtgcctt aacaccagga aaagacttgt tgataccgct catttccaac aagtattcac
    50941 ctgatgacgg agtcgttgag ctgaccatat aattttacct tgttggtcat acaataaggg
    51001 cgcagtaaac gactgcgccc aatcagtctt atttcttgct gaattcagcc aggttgtctt
    51061 tatctacgcc aacataaggt acgcggacca ctttgttgtc gattttccag ttggtgccat
    51121 cagccgcacc tttgccatcg gccaggtttt tcgccagatc aaaggtcgct ttcgcctggt
    51181 tgttagcatc gttcagtacg gtgcccgcca gtgcaccgga tttcaccagc gccagcgctt
    51241 ctggcagcgc atcgacgcca aacaccggaa tgctggactt gttgtgtgct ttcagtgctt
    51301 ctaccgcgcc cattgccatc gcgtcgttgt tggcgataac cacctcgatt ttgttggcgt
    51361 tcgggccaga cagccaggcg tccatcttat ctttcgcctg agcggtatcc cacatagcgg
    51421 tatctaactg taactgttca gttttaatgc ctttgtcgtt caattcttta atcacgtaag
    51481 tggtacgtgc ttctgcatcc ggatgccccg gctcaccttt cagcagtacg aattgaatct
    51541 gaccgtcttt gttcagatcc caaccctgat tcgccgccca gtgtttagca atcaaatcgc
    51601 cctgaataat gccggactct ttggagtcag tgccaacgta gtaggctttg tcgtagctat
    51661 ccagcgcctt acgagacggt tctttgttga agaaaaccac cggcacgttt tgcccacgcg
    51721 ctttctcaat caccgtaccc gcagctgccg ggtcaaccag gttgattgcc agtgccttca
    51781 cccctttcgc cagcaatacg tcgatctgat cgttctgctt ggactggtca ttctgagaat
    51841 cattcatcag cagctgaaca tctggcgcgg ctttcgcatc ttgctcaata gccttgcgca
    51901 ctacagacat aaagttatcg tcgtacttat agattgttac accaatgcga gtatcagcag
    51961 cgtgtgcagc ggcaccgaat aacatgctgg ccatcacagc agacagggtt aacaccttct
    52021 tattcatggt atctccggtt tttcttatgc agggtagtgc ttgagataaa tgctcggcgg
    52081 ggcagtagag ttaatgaagt gttactgaac gccgaagctc actttttaaa attcgttctt
    52141 ccatgcccgg taacgctcca gaaaacggct ttaattgttg ttatgacgct attacctcgg
    52201 tgaaagtgat tattcactgt tacatatggg ttacaacgtt aaaacggtgc aatcatagcc
    52261 atcacattgt taagatactg tgaaatcact cacagattga aagcggttac atcgcctgat
    52321 ttgttgagtt agtgatcgcc gccgcattct ggcgtgttgc gacagaatgg cgacgcacta
    52381 acgtcggcat aaaacagtgg ctggcacgag gatcaatatt gtctgctgcc ccctgcaagg
    52441 ccagttcggt agctaattta gccattgaag caatgggata acgcacggtc gttaattgcg
    52501 ggtcggtgta acgggcgatg ggaatatcat cgaaaccgat gattgagaga tgtagcggaa
    52561 tcgcaatgcc attatctttt aatgctgtca gtgcgccagc agccatattg tcgttataag
    52621 caaatacagc ggttagttgt agattgcgcc ccagcagttc aaccatcgcc gcctcaccgc
    52681 ccggcatgtc cggcgtacca gtgccaatcc agctttccgg cggaataata tcctgctctt
    52741 tcaacgcact catccagcct gctttacgca tggcgtcatc ttcaatgccg tggctggaag
    52801 aaagataacc aatacgttga tgaccgttat tcagcaacat gcgcgtcgcc attcgggcac
    52861 cgctgagatt atccaggcaa acgcaacgat gggcgtaccc cggcacaacg cggttgatta
    52921 acaccatacc aggaatgtta tccataaatt gtgccagttc atcgtcactc aatgcttttg
    52981 agtgaacaat caacgcatta caacgctggc gaattaacac ctcaatggcg tgacgctctt
    53041 tttccgcttc atgatagcta ttgccgatta gcacgtattt ctgatgctgc tgggcgacca
    53101 gatccaccgc ttttaccagc gcgccgaaaa aagcatcaga aacgtccatc accaccacgc
    53161 caatggtgtc gctaacctga gttgccagcg cctgggcatt ggcgtttggc cgataatcca
    53221 gctcactcac agctttcatt actgcttcac gcgtgtcggc actgaccagc gtgctgttat
    53281 tgagcacccg ggaaaccgtt gccacagaga cgccagcctg acgcgctaca tcacgaatgg
    53341 tgatcatatt cactacctgt tatgagattg cagtaaatga ctgcttgctg gcggctattt
    53401 tgtcagcact gaatacagga cttcgtgaat cgagtcacag caatggaaac ggttacagcc
    53461 gttttgttaa cgaatgtgat ccagatcgtt atcttgatgt tttagatatt gtcggtccgg
    53521 cagcacgcaa agttaactga cgccagagcc attccaccgg cccctggcgg aagtaacgca
    53581 gccagataac agagaagaag atattcgcca gccataccgg aataacaaac gccagcagct
    53641 ccagacggtc aaactgcata aacaaactga ggtggtaaaa aagcgtagta caaatcagcg
    53701 tttgcaatag atagttggtc agtgccatcc gtccgacaca ggcgattgcc agcaccagct
    53761 taaagcggct taattgcggc cagaagccat aaaacagcga cgcatagcca atcgcctgaa
    53821 acggcgcact cagttcccgc ggcatttgaa gtaagaaggc acaccagcga tacgcccagt
    53881 ccagctgcca ttgcagggcg atggcaggaa ggttaatgat caccccaatc gccaccagca
    53941 caaaaccagt acgacgatag tgacgtaagc tgaactgccc tttcagccag ccgctgcgca
    54001 tcagcgccgc accaatgagc atcatccctg ccagttgcca gccatactgt gcgcccagtg
    54061 ccagtaaact gttgccaaca ccatcggcac gattattgat cgcttcaaca ccaccgtgaa
    54121 gcttccagta tttttcatac aaaatagccg atgcatccgg cgtccaggcg cggctggtct
    54181 ggctgtcgga aatcagcccc aataacagca aaacgccaag ccccaccaga taaagcatga
    54241 cgcctgtatt aaacaggctt tttaccgatg gcgcatcgcg caccagccgc cagcagatta
    54301 agcccaccag tccgtaagcc agcagaatat cgccgtccca gaacaataaa ccgtgaataa
    54361 agcccagcaa gactaacagc gttaaccgcg actggatcca gcgtctgcca cggggcagca
    54421 acatttgcag gcccgcacca aacagcagcg caaaaagcgt gaggaatttc acctggccga
    54481 tgagatcgag aaatgcccag gtccatgcat cctgcggcgt aatagcgccg taccaggcgg
    54541 gattgagata agccgccttt ggtagcccaa aggcgctgat gtttaatagc aggatcccca
    54601 gaatggcgac gccgcgaaca aaatcgagcg tgacgttgcg ctccatggct cctgcctttt
    54661 aatcagttgt gatgacgcac agcgcgcaga aactcgtggc gcgtattctg actggatttg
    54721 aacaatccac caagagaggt cgttgttgtg gcactggttg cgtcgcggat gccacgcgct
    54781 ttcacgcagt aatgcaccgc gtcgatagag acagccacgt tattggtgcc cagcagcgtt
    54841 tgtagcgcaa tgagaatttg ctgcgtcaga cgttcctgca cctgcggacg ctgggcaaag
    54901 aactgcacga tgcggttaat ttttgacaga ccgatcaccg aatctttcgg gatataagcc
    54961 accgtcgctt tgccatctat ggtaacaaaa tggtgttcac aggtgctggt cagggtgata
    55021 tcgcgcacgg tgaccatttc atcgaccttc attttgtttt caatgagggt gattttcggg
    55081 aaattggcgt aatccagacc ggagaaaatt tcatcgacat acattttagc gatgcgatgc
    55141 ggcgtttcca tcaaactgtc atcagccagg tcgagattca gcagctgcat gatttcggtc
    55201 atatgaccag caataaggct tttgcgcgtt tcgttatcca tttcatgcac gggcgggcgc
    55261 agcggtgttt ccagtcctcg cgcaactaac gcttcatgaa ccagggccgc ttctttactg
    55321 agtgatggca tttatgattt ctcctgcagg tgtgacgcct ccgccctgcg tgggggcaaa
    55381 gttattaagc tgatttacag cctgattatt gtgcgtgagg cggcgcacat aatccagtat
    55441 tcacagcgat aattattgta attgccgctg cctttcatca gcagatgtta aaacatcgtt
    55501 atgcaaatac ggaagtgaaa gttactcaca gcacattgaa taaacggtat gatgaagaaa
    55561 ttgcaaacaa cacaacaagg agccacgcat ggaaatgctc gaagagcacc gctgttttga
    55621 aggctggcag caacgctggc gacacgactc cagtacctta aactgcccga tgacgttcag
    55681 tatctttctc ccaccacctc gtgatcacac cccgccacca gtgctgtact ggctttccgg
    55741 attaacctgc aatgacgaga acttcaccac caaggcgggt gcccagcgcg tggcggcgga
    55801 actggggatt gtactggtaa tgccagacac cagcccgcgc ggcgaacagg ttgccaacga
    55861 cgatggctac gatttaggcc agggcgcggg gttttatctt aacgccacgc aaccaccgtg
    55921 ggcgacgcat taccagatgt atgattatct gcgcgatgaa ttaccggcac tgattcagtc
    55981 gcaatttaat gtcagcgacc gctgcgctat tagcggtcat tccatgggtg gtcacggcgc
    56041 gctgattatg gcgctgaaaa atccgggtaa atacaccagc gtttccgcct ttgcgccaat
    56101 tgtgaatccg tgcagcgtcc cgtggggaat caaagcgttt agcacttatt taggtgagga
    56161 caaaaatgca tggctggaat gggacagttg cgcgttgatg tatgccagta acgcgcagga
    56221 tgcaatcccg acgcttattg atcagggtga taatgatcag tttcttgctg accaactgca
    56281 acctgcagta ctggcagaag ccgcgcgcca gaaagcgtgg ccgatgacgc tgcgtattca
    56341 gccgggatat gatcacagtt actacttcat cgcctctttt atagaggatc acctgcgctt
    56401 ccatgcgcag tatttactga agtgaaagtc cgcccggttc gccgggcatc ttctcatcag
    56461 aagcgataat ccactgccat aaagtaacga cgtccgtctt cgttatagct gtagtcgtca
    56521 cgactgagat ccttgtcgcc aaggttcagc acgcctgcac gcagtttgac gtctttagtc
    56581 acctgccagg ccgcgccggt attccagatg gtataaccgc ccggtgtttt agccgtcgcg
    56641 ctgtcggcgc gtttctgccc ggtatagtga ccagaaacat agaatgacca gtcttccagc
    56701 gccagcggtt tccagtccag cgtaccgtta gcagtatgga acggcagatc ggatagcggt
    56761 ttgttttcgc cgttgctgac atcacgacca tcgttgtagg tgtagttgat cgacagtttc
    56821 cattcatcgt tgaacggaat tttcagttcg gtttccacgc cctgaatacg tgctttgtta
    56881 acgttgtagt agctaaatac cggtatgcgc cgtccgttag cgcccgtctc aaaaccgaca
    56941 aagttttggt agcccggtgc agcgttgacg tcagacgtac ggctaatgct gatacgatct
    57001 ttcacatcgt tacggaaaac ggtaacgctg gattcaaccc cttccagcca gccttcttcg
    57061 cccatgtagt aaagccccag ttcccaactt tcgctggttt ctggtttcag atccgggcta
    57121 cccacaatct tacatgcgcc acggcaggaa ttgctcgtcc agtcagggct aagttgcaac
    57181 agagaaggtg ctttaaatgc cgtcgcccag ccccctttca ccgttacggt gtcggtggcg
    57241 ttataaacca ggtaggcacg cggactccag tgttcaccgt aggtttcgtg atcgtccata
    57301 cgcacgccgg tcgtcagcgc cagcggctcg aagatccgcc attcatcttc cacaaacagc
    57361 gcgtactggc tggcagacgt tttggagctg gttcccccgg tcaggttcac cgcatcgcta
    57421 agtttgtcgt gacgccattc accgccaacc gtgagaaact gattaatcgc cgtcagcggc
    57481 aacgtgtatt tgccgtcgac cgtattgctt tcggaagtta tcgggctgct gttgccaggg
    57541 tttttgttct cgactttctc accgtagtat ttcagttcgc tggtgccgta atcccaacgc
    57601 ccattatggc tgacggagta gttctggcgt tccaggcggt ttttgtccag cgagtcggaa
    57661 tcacgatcct gacggtcgaa accgtatccg gcagtaaaat cgtgattttg attcggtgtc
    57721 caggcaaatt cgacattgcc gtcgcggctg gagaatcctt caatacgcgg cgtttctccg
    57781 gtatcggtgg tcgttgagtt ttgcgggtca tccttttcac gttttgccag gctgccgtaa
    57841 gctttcattc ccagcacgcc gtcaattaat ggtccgctgg taaagaactg accgttatag
    57901 gtatcaccgc gatcgcgatg ttcctgaacg gtggtatcga cggtaacggt gcccgaccat
    57961 ttctgaccga tttttttggt gatgatattc actacaccgc cgagcgcatc ggaaccgtac
    58021 agcgacgaca tcgggccacg gaccacttca atacgttcga tggaatcgac cgggatccag
    58081 ttcagatcga aatcattgtg gcggaagacg gcattgcggg agttaacgcg tttaccgtcg
    58141 acaagaatca gggtgtagct gctgtccaga ccacgaatac ttacgccctt acggttatcc
    58201 ccttcgttcg tcagttgtac gccaggcact tctttgagga catccttcag attctgtacc
    58261 ggttttcgct gcaggtcttc ctgggtaatg acgctgatac tggcgggagc atctttaagg
    58321 ttttgttcaa cggaagatgc agtgacaacc atcgtttcgc catcatcatc gaccgctaac
    58381 acaggccatg cacaagaaat agcggacaaa cacagcccga cccgtacgaa agggttcaac
    58441 ctaaacattc catatctcca tgaggtaact acgaaaataa aatgggtatc gctcacatct
    58501 tctttacgtc cccttgcgta cggcagcatc gcggtggact tatttgtatg caggtgatca
    58561 tcccagaaag ccggaacagc ctctgatttg tcagcctttt ttgattgcgg cgtaacgata
    58621 atgcaaacga taacaattat caatccaaat gttaaatttt atatccgcat gatttgtcag
    58681 ggaaatggaa ttgaaaaagc cctctcggtt gagagggctt agcaaggaag ggaggaaact
    58741 tatttcttat cgttctgcgg gaacttcatt tcgctgtagc gtacgaagtg agttccttta
    58801 atcagcttat agccgaacca aataatcagg aacagcggga taccaatata cgttgccgct
    58861 acgccgcccc agtcaatggt atctttcagg aacgcttcgt agttctggcc caaagtgata
    58921 atcagacaca gaatgaatgc gaagatcggc cccagtggga agaaacctga acggtacggc
    58981 agatcgttaa tgtcgtgtcc ctgcaatacg tacccgcgac ggaaacgata gtggctaatg
    59041 gcaatcccca gccaggcgat aaaacccgtc atcccggagg tgttcagcag ccacaggtat
    59101 accgtctggt tgccaaacat ggaggtcagg aagcacaaac cggcaatcac cgtcgtcgca
    59161 tacagcgcat tacgcggcac gccaccacgc gacagtttag cgaaaatgcg cggcgcttta
    59221 ccgtcacacg ccagggtgta cagcatacga gtagacgcat acataccgga gttacccgct
    59281 gacagcaccg ccgtcagaat aactgcgttc atcaccgccg ccgcagagag cagacccgcg
    59341 tgctggaaca ccagggtgaa cggactgacg ctgatgtctt taacatcgtt acgcagcagg
    59401 ctcggatcgg tgtacggaat aatcaggctg ataatcagga tcgcgaacac atagaacaac
    59461 aggattcgcc agaatacctg acgtaccgcg cgtggaatgt ttttcgccgg atcttcggac
    59521 tcgcctgcag caataccgat cagctcggtt ccctggaaag agaagccgac aatcatagct
    59581 acgccgatca tcgccgcaaa accaccagca aacggcgctt cgccgattgt ccagttgctc
    59641 cagcccgcag gctgcgcgcc tttgaagata ccgataatca tcagcacgcc aacgatgata
    59701 aagacaataa ctgtcgtgac tttgatcagt gagaaccagt attccgcttc accaaagccg
    59761 cgaacagaga tgtagttcaa caggaagata acgccgagga acaacgcact ccagatccag
    59821 cccggtgtat ccgggaacca ccagctcatg accagctgtg ctgcaaccag gtcaacggca
    59881 atagtcaccg cccagttgta ccagtagttc cagcccagcg cgaagccaaa gccttcttca
    59941 acatagttct gaccgtacgt ggcaaacgaa ccggaaaccg gcatatatgc agccagttca
    60001 ccgagactgg tcatcaggaa gtaaaccatc aggccaatca gcatatacga gagcaatgcc
    60061 ccgcccggac ctgcctgaga aatcgttgcg ccagaggcaa caaaaagacc tgtaccgatg
    60121 gaaccgccaa tggcaatcat cgtcaggtga cgcgccttca attcacggcg taagcccggc
    60181 gcttctgtag ttttagtttc ggaacccata caaaaatgct atccatctta aaaatgaggc
    60241 gcgattgtag cagacgattg gcaatccttc cggcagaaat acacggttat aagacacctt
    60301 catgatcgcc cagggattat aagtaaagca gccaatctct tttctggcga atgcatgctg
    60361 agggcgctgc gtcacgaaat cgacacagca ccagcatgtt cttgtacagc accttaacgc
    60421 ggtacattcg cgggatcgca atagtccaga aagcgccgta gcgcgttgga aaggtgtttt
    60481 tgccgatgat gtatacgcca caacgtacgc atcaggcgcg gcagagggac cgcaacttca
    60541 cttaatgtgc ctgcctgcaa ttgatcttca atcacccgtc gcgacaggca actaattccc
    60601 aacccatgac gcaccgcatg tttgattgcc tcggagttac ctaattccat cgccatctca
    60661 aacttcggta aatgtgacag caacagataa tcgacaatct cccgcgtgcc ggaaccgcgt
    60721 tcacgcagga tccacggcgc agcggccagc tgttctaagg tgaccggacc acgagccaac
    60781 ggcgaagtcg gcgcggcgaa aaccaccagc tcgtcttcca gccacggttc agaaatgatt
    60841 tcagtgctgt ggcacggtcc ttcaataaag ccaatatcaa cgcggaaatc cagcaccgct
    60901 tgcatcacgt cctggctatt cccaacgcta agttcaatcg gcaactgcgg ataatcatgg
    60961 cgataacggg cgataactgc aggtagaatg tagttaccga tggtactact ggcatagata
    61021 cgaatcgcgc cgttgtcttc gcgaaacagt tgttcgattt caaccgcctg ttcaagcagt
    61081 gccaacgctc gcggatagag cagccgcccg tgttcattaa caaccagtct tttccccacg
    61141 cgatcaaaca gttgaacgcc aagctgccct tccaggtcgg tcaaggctgc gctcactgct
    61201 gattgcgaca acgccagcat caccgacgcc tgggtggttg atccactttt caatacttct
    61261 gcaaaaactt ccaactgccg gagg
//
LOCUS       DAPOXO010000019        61083 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPOXO010000019 DAPOXO010000000
VERSION     DAPOXO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 61083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61083
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.019"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            202..1290
                     /gene="ompF"
                     /locus_tag="ROH59_001487"
     CDS             202..1290
                     /gene="ompF"
                     /locus_tag="ROH59_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HDX4803994.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKGNGEDSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQDNNSEGADAQTGNK
                     TRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADR
                     TNLQEESPLGKGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKT
                     QDVLLVAQYQFDFGLRPSIAYTKSKAKDVDGIGDVDLVNYFEVGATYYFNKNMSTYVD
                     YIINQIDSDNKLGVGSDDTVAVGIVYQF"
     gene            1475..2665
                     /gene="aspC"
                     /locus_tag="ROH59_001488"
     CDS             1475..2665
                     /gene="aspC"
                     /locus_tag="ROH59_001488"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HDX4803995.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAALHKELIVASSYSKNFGLYNERVGACTLVAADSETVERAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(2715..3362)
                     /gene="gloC"
                     /locus_tag="ROH59_001489"
     CDS             complement(2715..3362)
                     /gene="gloC"
                     /locus_tag="ROH59_001489"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HDX4803996.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDA
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFNEQARLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW"
     gene            complement(3389..3937)
                     /locus_tag="ROH59_001490"
     CDS             complement(3389..3937)
                     /locus_tag="ROH59_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HDX4803997.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            complement(4118..5965)
                     /gene="ldtD"
                     /locus_tag="ROH59_001491"
     CDS             complement(4118..5965)
                     /gene="ldtD"
                     /locus_tag="ROH59_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDX4803998.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLSDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDAVVSPSAVTVETAETKLMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            complement(6226..10686)
                     /gene="mukB"
                     /locus_tag="ROH59_001492"
     CDS             complement(6226..10686)
                     /gene="mukB"
                     /locus_tag="ROH59_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HDX4803999.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVWKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQDVTEFLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLNQYNQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS"
     gene            complement(10686..11390)
                     /gene="mukE"
                     /locus_tag="ROH59_001493"
     CDS             complement(10686..11390)
                     /gene="mukE"
                     /locus_tag="ROH59_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HDX4804000.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEESQPDSGEEE"
     gene            complement(11371..12693)
                     /gene="mukF"
                     /locus_tag="ROH59_001494"
     CDS             complement(11371..12693)
                     /gene="mukF"
                     /locus_tag="ROH59_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HDX4804001.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMVLR
                     DEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            complement(12690..13475)
                     /gene="cmoM"
                     /locus_tag="ROH59_001495"
     CDS             complement(12690..13475)
                     /gene="cmoM"
                     /locus_tag="ROH59_001495"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HDX4804002.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEIGPQ
                     KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQILGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            13611..14390
                     /gene="elyC"
                     /locus_tag="ROH59_001496"
     CDS             13611..14390
                     /gene="elyC"
                     /locus_tag="ROH59_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HDX4804003.1"
                     /translation="MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGSSGEPRQE"
     gene            complement(14367..15260)
                     /locus_tag="ROH59_001497"
     CDS             complement(14367..15260)
                     /locus_tag="ROH59_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HDX4804004.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     ARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
                     QFNNTGLSMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFNRRNFDLASKSLLPWLA"
     gene            complement(15414..16160)
                     /gene="kdsB"
                     /locus_tag="ROH59_001498"
     CDS             complement(15414..16160)
                     /gene="kdsB"
                     /locus_tag="ROH59_001498"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HDX4804005.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAKDLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAQEVPGTGVDTPEDLERVRAEMR"
     gene            complement(16157..16339)
                     /gene="ycaR"
                     /locus_tag="ROH59_001499"
     CDS             complement(16157..16339)
                     /gene="ycaR"
                     /locus_tag="ROH59_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HDX4804006.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADEGKS"
     gene            complement(16391..17623)
                     /locus_tag="ROH59_001500"
     CDS             complement(16391..17623)
                     /locus_tag="ROH59_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaQ family DNA glycosylase"
                     /protein_id="HDX4804007.1"
                     /translation="MSLPHLSLADARNLHLAAQGLLNKPHRRASLEDIPATISRMSLL
                     QIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGELMEYWAHEACFMPRSDFRLIRH
                     RMLAPEKMGWKYKDAWMQEHAAEIALLIQHIHDRGPVRSADFEHPRKGASGWWEWKPH
                     KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQAEAEIIMLDNSARS
                     LGIFREQWLADYYRLKRPALAAWREARAEQQQIIAVHVEKLGNLWLHADLLPLLERAL
                     AGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKRQYGYFVLPLLHRGQ
                     LVGRMDSKMHRQKGILEVISLWLQEGIKPTTTLQKGLRQAITDFANWQQATRVTLGRC
                     SQGLFTDCRAGWEIDPVA"
     gene            complement(17660..18646)
                     /gene="lpxK"
                     /locus_tag="ROH59_001501"
     CDS             complement(17660..18646)
                     /gene="lpxK"
                     /locus_tag="ROH59_001501"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HDX4804008.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTGAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKLVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVAQLEHVVAIAGIGHPPRFFATLKMCGVQPEKCVPLADHQFLNHADVSALV
                     SAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGN"
     gene            complement(18643..20391)
                     /gene="msbA"
                     /locus_tag="ROH59_001502"
     CDS             complement(18643..20391)
                     /gene="msbA"
                     /locus_tag="ROH59_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HDX4804009.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLMWMPLVVIGLMILRGITSYISSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            complement(20428..22692)
                     /locus_tag="ROH59_001503"
     CDS             complement(20428..22692)
                     /locus_tag="ROH59_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309023.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HDX4804010.1"
                     /translation="MKITTVGVCIICGIFPLLILPQLPGTVTLAFLTLFACVLAFIPV
                     KTVRYIALTLLFFVWGILAAKQILWAGETLTGATQDAIVEIIATDGMTTHYGQITHLQ
                     GRRIFPAPGLVLYGEYLPQAVCAGQVWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYMWNAVILGLGMGERLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRGGQVFLPGCWLHWQMPLIGGICCAAFYAWLTG
                     MQPPALRTVVALAIWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANL
                     FAIPLVTFITVPLILAAMVVHLSGPFILEQGLWFLADRSLALLFWGLKSLPEGWINIA
                     ERWQWLTFSPWFLLVVWRLNAWRTLPAMCVAVGLLMCLPLWQKPRPDEWQVYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGSNDKGNNHSCVVK
                     IDDGTNSILLTGDIEAPAEQKMLSRYWQQMQATLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSSKVKYRYHQQGYKWLDTPHQGQITVNFSAQGWWISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            complement(22898..23182)
                     /gene="ihfB"
                     /locus_tag="ROH59_001504"
     CDS             complement(22898..23182)
                     /gene="ihfB"
                     /locus_tag="ROH59_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HDX4804011.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            complement(23342..25015)
                     /gene="rpsA"
                     /locus_tag="ROH59_001505"
     CDS             complement(23342..25015)
                     /gene="rpsA"
                     /locus_tag="ROH59_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDX4804012.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            complement(25126..25809)
                     /gene="cmk"
                     /locus_tag="ROH59_001506"
     CDS             complement(25126..25809)
                     /gene="cmk"
                     /locus_tag="ROH59_001506"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDX4804013.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQ
                     YARQKLALA"
     gene            complement(25982..26764)
                     /gene="ycaL"
                     /locus_tag="ROH59_001507"
     CDS             complement(25982..26764)
                     /gene="ycaL"
                     /locus_tag="ROH59_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase YcaL"
                     /protein_id="HDX4804014.1"
                     /translation="MYLKSNQKNTKLLLAIATSAALLTGCQNTHGINTDLAISSGLNA
                     YKAATLSDADAKAIANQGCVEMDSGNKVASKSSKYGKRLAKIAKALGNNINGTPVNYK
                     VYMTSDVNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAI
                     VAARDAISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQ
                     GLVGSFEKLASLDGGHTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            complement(26908..27297)
                     /locus_tag="ROH59_001508"
     CDS             complement(26908..27297)
                     /locus_tag="ROH59_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDX4804015.1"
                     /translation="MSDLNQFRSKGPELLVELAQHTSETVREIIDIEPEVADQIGQAV
                     ANRMMQVWGGQNVYFPMGMVWKVSQRDREIFREFNGRNHHELARKFGVSLQWVYSVVK
                     RVRKEELDRMQGKLFADEPDADTEKKE"
     gene            complement(27269..27718)
                     /locus_tag="ROH59_001509"
     CDS             complement(27269..27718)
                     /locus_tag="ROH59_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein GemA"
                     /protein_id="HDX4804016.1"
                     /translation="MQKKRLIQLIHIARNELGMDEDTYRQMLQGLTGKASTKGMDTTQ
                     LNCVLESMKKKGFRVKPARKASSGLPLDNHPQSRKIRALWLEMAAAGIVRDRSENALA
                     RWIKRETGISALRWLSTEQASSVIEKLKKWQRRAAGVKHERPESVSK"
     gene            complement(27720..27926)
                     /locus_tag="ROH59_001510"
     CDS             complement(27720..27926)
                     /locus_tag="ROH59_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001489320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804017.1"
                     /translation="MTTETIVCFLFWYMYAGSCSARLHRSLGYGRHYDTAHYILYMTA
                     VMLFWPVTLPAATDIVADRLKKRR"
     gene            complement(27916..28146)
                     /locus_tag="ROH59_001511"
     CDS             complement(27916..28146)
                     /locus_tag="ROH59_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804018.1"
                     /translation="MITLSGKSRKLKACRISARYLFARAFFKNVRPGITIGVIAGREQ
                     VEKYMSGAWWNNDPVIAARNIHIEWGGIQNDY"
     gene            complement(28143..28826)
                     /locus_tag="ROH59_001512"
     CDS             complement(28143..28826)
                     /locus_tag="ROH59_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HDX4804019.1"
                     /translation="MTDQNKHIEKLKKLLALAASGNPHEAALALRRARKLMDVHGITH
                     SDIAMSDIDETISHYWPTGSLRPPRYMLGLMNIIREVFGVNSIIHPGTHPSVGFYGNR
                     ERAALAAYTWEVLARQLKKARQQYISAQNKRIKTATRTSRGDQFAEGWVLAVISEIQS
                     FALTDDERELMQQWLEHKYPQTQTTRARKPGRSRNGDASRYAGFREGQNVRLHRPVSG
                     QEQQKLEAR"
     gene            complement(28823..29038)
                     /locus_tag="ROH59_001513"
     CDS             complement(28823..29038)
                     /locus_tag="ROH59_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804020.1"
                     /translation="MADILREITAWTLILTGLATCLSAGAALAALLMHITTQWLWEKL
                     KAAYSLKELSDAVRAWKRQKNTGDTEQ"
     gene            complement(29053..29349)
                     /locus_tag="ROH59_001514"
     CDS             complement(29053..29349)
                     /locus_tag="ROH59_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804021.1"
                     /translation="MTRNTELTRTALYRLALQRFGPDAQALKLAEEAAELAASAARNL
                     NGQGSESDLAAELADVEIMTEQLRLQGMDRLIDFHKQKKLERLAARLGVIYTNE"
     gene            complement(29359..29631)
                     /locus_tag="ROH59_001515"
     CDS             complement(29359..29631)
                     /locus_tag="ROH59_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804022.1"
                     /translation="MITPQEARQRTRTLVEHYVNECECRDLTDVKHVLTALISMATQA
                     IVATNGKEAALQVLMNTLTHTAEHEVPYRMETTAEGGLHITVSRKH"
     gene            complement(29920..30450)
                     /locus_tag="ROH59_001516"
     CDS             complement(29920..30450)
                     /locus_tag="ROH59_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="HDX4804023.1"
                     /translation="MAKSTKGAKRIKAAAALWVPGTREEVIEGIRLLGDAQRELVRAE
                     TEMNDAIGDITARYAPLTESLKKRMAELQSGIQTWCEAHRDELTGNGKVKFANLTTGE
                     VQWRNRPPSVSIRGADNVIELLRRLGLERFIRVKEEINKDAILNEKEAVKNIPGISIK
                     SDIEDFSIIPFEQDVQ"
     gene            complement(30478..30747)
                     /locus_tag="ROH59_001517"
     CDS             complement(30478..30747)
                     /locus_tag="ROH59_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804024.1"
                     /translation="MKSTTGINQQISKVQSAIMALKATNTDVQSITIRGNKPVIRVSR
                     SAHCMRMLEQGKACYLYTGHDHRGYFRQGVFELHGCRVVWPESLW"
     gene            complement(30750..31916)
                     /locus_tag="ROH59_001518"
     CDS             complement(30750..31916)
                     /locus_tag="ROH59_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX4804025.1"
                     /translation="MLVLKQQLKEARIPQAVVARAVDVSEATLAQIVNHNAWPRTSPG
                     EVRRRLASWLESQGIDTTKSFDAVQGAATPRTAGTTDKTSLSEEENMLLKKQVLFPAT
                     KKAFGLFRDPFADEAMQGSDDVFTTPDIRYVREALYQTARHGGFMAVIGESGAGKSTL
                     RRDLTERINRENAPVIVIEPYIIAMEDNDVKGKTLKAAAIAEAIISTIAPLESIRRSQ
                     DARFRQLHRVLKDSSQAGFSHVLVIEEAHSLPIPTLKHLKRFFELESGFKKLLSIVLI
                     GQPELATKLSERNMEVREVVQRCEVVELLPLDNNLEEFLTFKLQRAGKQLTDIMDAGA
                     VDAIRARLSNPGSHRKNMVSLLYPLAVSNLVIAAMNLAAEIGVPQVNADVVKGV"
     gene            complement(31927..33696)
                     /locus_tag="ROH59_001519"
     CDS             complement(31927..33696)
                     /locus_tag="ROH59_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDX4804026.1"
                     /translation="MTPALTEKLVETARAARDAGHGKRGAIYDAACAELGMSRATLLR
                     RLKEVSVTDKRKKRADAGRSALTRDEAALISATLREATRKNGKRLYSIADAVETLRAN
                     GFITAGRTDETTSEFFPLSEDAISRALRNYGLHPEQLDAPAPHTEVASLHPNHVWQID
                     ASLCTLYYLSNGHKGLQVMDSAKFYKNKPANLARIASDRVWSYEITDHASGWIYVEYV
                     TGAESGENLCSVLINAMQERGGADVLHGVPKILYLDPGSANTAGMTKNMCRSLGIDLI
                     AHKPHNARATGQVEKARDIIERKLEPGLKFRPVHSLEELNALAAKWRSHFNATAVHSR
                     HGKTRTDIWLKITAEQLKKAPSVEVCRELAVAAPELRKVTPKLRVSFRGTEFDVSTVP
                     GVLVGEKLMITRNPWRSDVAQVVLTGEDGHETFFLVEEVRKNEFGFAEGAAVFGESYK
                     ALPETPAQMAAKETEALVTGTDNAADAAAARKAKALPFGGRLDPYKHIDDTTLPAYMP
                     KRGQASDVRGPRTEQRPMTHVEAAKALRDKFSADGLTWTPEHYRQLTAQYPDGVPEAA
                     LDEVMATLTTPARSSVISIVNGN"
     gene            complement(33712..34029)
                     /locus_tag="ROH59_001520"
     CDS             complement(33712..34029)
                     /locus_tag="ROH59_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804027.1"
                     /translation="MNTNNTQNTLMDSPEALGHALCNLLPEMVQGFRVVTPSGEICVP
                     AQETHPFVLTMEVMLMQQIRRLQNQSALRPVVAPQPVNTVVKTCDGETLCDLARKIAA
                     RIG"
     gene            complement(34029..34949)
                     /locus_tag="ROH59_001521"
     CDS             complement(34029..34949)
                     /locus_tag="ROH59_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001488438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3102 domain-containing protein"
                     /protein_id="HDX4804028.1"
                     /translation="MGRTKSPINTELNADVPLSDDLNVSLNAMTQHRMEIMQQFGDGL
                     PYERERIVHEARFYMAQSAESMLEAGKRLIILKENEPHGDFTNILENDLGLAPQVARR
                     MMQASVKFLGNGDEQPKRSALSVLGKTKLYELMVLDDEELDALADGGTVAGATLDDID
                     RMTSRELKAALREARETNAAQQQVLAGKDEKINELATKLEKKSRLQPPPPDEELKKLR
                     AEVTALAVEAESAIAVRLSSVFETLCEYCTKNMIDTPRDFMAGLVCQIERSVHALRET
                     FDLEAAPSGNDAPAWLTEPEPEINRPEDMQ"
     gene            complement(34960..35268)
                     /locus_tag="ROH59_001522"
     CDS             complement(34960..35268)
                     /locus_tag="ROH59_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4804029.1"
                     /translation="MSKTNVSSSGSRILRVLKALRGHALNGISNGELATALHESPANI
                     NRALNTLIEEGLALKLENGRFAPGIQLLQIAMAHSNEMARAQDRINEINQRVISGSRL
                     "
     gene            complement(35321..35509)
                     /locus_tag="ROH59_001523"
     CDS             complement(35321..35509)
                     /locus_tag="ROH59_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001510316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDX4804030.1"
                     /translation="MTAEQVKALFRQRGITFTRWAEENGYNRNEVYRVLNGQTKARYG
                     KSHEIAVKLGLKSTAQAA"
     gene            35603..35959
                     /locus_tag="ROH59_001524"
     CDS             35603..35959
                     /locus_tag="ROH59_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4804031.1"
                     /translation="MSKDIGERVISVRKKAGLNQREFAARLGISNGGISQIENGKAMP
                     GGEFLLKMHQEFNVDVNWLLTGMSTDGMTRNQNQISPEKQKLIDTFDDMTPDQQRSFL
                     EIGRFYTQPKPGKIAG"
     gene            complement(36076..36840)
                     /locus_tag="ROH59_001525"
     CDS             complement(36076..36840)
                     /locus_tag="ROH59_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HDX4804032.1"
                     /translation="MKMQTLPIVPWIGGKRRLAKHILPLFPAHECYVEPFCGAAALYF
                     LKTPGKIEVINDINGELVNLYRVVKHHLEEFVRQFKWALVSRQIYKWLQITPEETLTD
                     IQRAARFYYLQKQAFGGKVAEHSFGTSTTSPPRFNLLRIEEELSAAHLRLSRTVIEHM
                     DWQQCIERYDRPHTLFYCDPPYLGTEGYGVDFPEGNYSRLAELARCIRGKMIISVNDI
                     PQMREVFTGLNIQTVNINYSLAGKPTPRRELLICNF"
     gene            complement(37031..37246)
                     /locus_tag="ROH59_001526"
     CDS             complement(37031..37246)
                     /locus_tag="ROH59_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804033.1"
                     /translation="MNPRLTLTEHQRRAEAVNNVLEDIIRLYRGELSVCRAAFHFQGI
                     QKQFDTSVFAEGITYALDRIRSENRPG"
     gene            37248..37649
                     /locus_tag="ROH59_001527"
     CDS             37248..37649
                     /locus_tag="ROH59_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001534496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804034.1"
                     /translation="MHSLNDDFYVLTGKIFCRLLNTHPAPQVLIYSGFFDIPDQVDHD
                     QKKCRCFIDTLIWLRDNSYIRYSQLLAVGAADVVLTEKTLCLLNAMPTFLQPRPVPFK
                     ESLLDAVKTGENAVIAECVSRIMRYVFNERK"
     gene            complement(37625..38353)
                     /locus_tag="ROH59_001528"
     CDS             complement(37625..38353)
                     /locus_tag="ROH59_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804035.1"
                     /translation="MTQTLNPVITVTVSGPVGSGKSYVLARIEEVVKQEFGNSVIVDA
                     ADVDGERRMSGDDLSTWQKPRAGTVIRLEEYTGQGLLSYGEERICRTNELLDVICPTG
                     RQPWILPDALHATIAALMTVYDQELLMKELRKLTGQSTECCSSPKYGKQEHIPINQPP
                     RFFDEYLLTPENKAEHEEIKAALFREIRKIAEMQLEGGLDRVMARGEWASLFERVSPE
                     LLPLALAIGIMQTADKPHLRSLNT"
     gene            38484..38834
                     /locus_tag="ROH59_001529"
     CDS             38484..38834
                     /locus_tag="ROH59_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin"
                     /protein_id="HDX4804036.1"
                     /translation="MKNLKKFIPPVKKPRLSGWLLTSVLLLGTIALVSPQQLPVVIYK
                     LALITLAAVLGYWLDRSLFPKARPGQYLKHDDRLMAEGRFPVQTGLHLVFSAALIRRA
                     LIVAAVCLAVAMGL"
     gene            38837..39577
                     /locus_tag="ROH59_001530"
     CDS             38837..39577
                     /locus_tag="ROH59_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDX4804037.1"
                     /translation="MNWPQITWIVCMSLKLAFEAFRVFIRTERLSVRAGTFLVHMAWV
                     FFVAMLLWCGGFFSQACAAQPPQAALQYRDDVIRNARLEWGLSAPVADFAAQLHQESG
                     WRPDAISPAGAQGLAQFMPATADWISQLIPMLSSREPFNPAWAIRALVSYDRWLWQRV
                     SAASDCERMAMTLSGYNGGLGWVQRDRRLASQKGLDSTRWFGHVATVNAGRNAASWRE
                     NRHYPQRILRELAPRYLTWGGSSCVASG"
     gene            39561..40211
                     /locus_tag="ROH59_001531"
     CDS             39561..40211
                     /locus_tag="ROH59_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000264665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804038.1"
                     /translation="MWHLVKKLPWRGILLAILINAFLVGLYAMGYRSGHDSAKRDGDT
                     ALSQLQSAFDAYKTEQATLENAALRAWARRYQEQVAAGQRAEAGYLEQIAQLESRNKQ
                     LQGQINDVTQRWIDEKGKSHPIECVFTRGFVRQYNAALGYDNASVDTGHSDSVAATGT
                     RSGTATGQPETTDTRLRDSGVSQRDVLANIIDNAWQCRRWRNQINALLDEREGLQK"
     gene            40208..40534
                     /locus_tag="ROH59_001532"
     CDS             40208..40534
                     /locus_tag="ROH59_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804039.1"
                     /translation="MTLQVEFWTVVSFLLTFMRFVGGLAKWLFSKTEERQAARFASLE
                     QALQQSASNWGELEKEFMRFKADLPLNYVRREDYIRGQTVIEAKLDALYNKLEVVQQY
                     RNTGGQ"
     gene            40534..40845
                     /locus_tag="ROH59_001533"
     CDS             40534..40845
                     /locus_tag="ROH59_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804040.1"
                     /translation="MVDITRVRRESLRWSLLVALNKTRPYTASETLLLDVSRAIYPDT
                     TPLELRRELDYLADRKMVELEKKPSGDWFADLTRLGVDLVEYTVECGPGIARPEKYWS
                     E"
     gene            40845..41390
                     /locus_tag="ROH59_001534"
     CDS             40845..41390
                     /locus_tag="ROH59_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3486 family protein"
                     /protein_id="HDX4804041.1"
                     /translation="MARRSTIEKLPEDVRRWLERALTESGFSGYNELESLLRERGYVI
                     SKSAIHRYGQKIERRYGAIRAATEAARMLTEGAADDQDARSEAVIALIQTELFESIVQ
                     LQEAEEGEVDPKERVALLSKVAKNVATLSRASVNLKKFQSEVRARAQQAASNAEKIAR
                     KGGLSSDAVQALRREILGIAT"
     gene            41441..42982
                     /locus_tag="ROH59_001535"
     CDS             41441..42982
                     /locus_tag="ROH59_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804042.1"
                     /translation="MSPMDGRNNLAPVLPDTSALDAPPVLLPYQQRWVADTSPLKVIE
                     KSRRTGITWAEASDNVLTAASSAPAGGMNVYYIAYNQDMTVEYIQACAMWARAFNYAA
                     SEIEEGFWEEDDDDKHIKTYTIKFPDSGFRIVALSSRPSNLRGRQGIIVIDEAAFHEQ
                     LDELLKAALAMLIWGGKVRVISTHDGDDNPFNTLIGDIRAGRQGGSIHRITFREAVSE
                     GLFRRVCLRTGKEWSEASEQAWMASVYKFYGAGASEELDCIPANGGGAWLSRALIESR
                     MSADTPVLRLTCKEGYELLSDEVRFRETQDWLDEYLKPLLEALPTDARSFLGRDFGRS
                     GDLSVDYPLLQEKNLVRRVPFVLELRNVPFRQQEQITWYLMDGLPGLLGAAFDARGNG
                     AYLAEYAMQRYGSGRVQQVMPTEGWYREHMPPVKAALEDGNLVDLPKDEDTLDDLRAV
                     QVVNGVPRVPEQRSKAKADGGKRHGDSAIALALAYFASREINKGPVKASSRRRRQAAR
                     MLEGF"
     gene            42982..44478
                     /locus_tag="ROH59_001536"
     CDS             42982..44478
                     /locus_tag="ROH59_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF935 domain-containing protein"
                     /protein_id="HDX4804043.1"
                     /translation="MARGIWVSPDEFVAFSEPQKSLTAQIASRSRAIDFYGLGMYLPN
                     PDPILKAQGRDIRIYRELRTDPLVGGCIRRRKAALKSLERGLERGHASARVFRFIRDM
                     LDDLDLSRIIGEMSDAVLYGYQPCEIMWGRSVRSWAVTDIVGKPPEWFQFDTDNCLRF
                     RARDAGVEGELLSPSKFVVPAQDASYDNPYGFPDLSMCFWPVAFKKGGMKFWLRFAEK
                     FGSPWVIGKHPRGANDAEIEKLLDSMEQMVEDAVAAIPDDSSIELRAADGKADSSEVF
                     RELITLSRSEISIALLGQNQTTEANSNKASAQAGLEVTADIRDADADIIQAAVNQVIR
                     TVVTLNFGDVPCPVWAMWEQEAIDDTRATRDEKLTRAGLRLTPQYFKREYQLQDGDID
                     ETPPSERQNNMLPLSFAEAIDADIQAQQQLDDALDILMNGGALNGTLEPVLAPLFRRV
                     ENGVNPSELLGELAELYPQMNTDDLQERLARILFVANIRGRLHERDNG"
     gene            44459..45280
                     /locus_tag="ROH59_001537"
     CDS             44459..45280
                     /locus_tag="ROH59_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDX4804044.1"
                     /translation="MSVTTAELAYCMTLPPKRAINYLKSKGYQITWDWEEMWQEAHAR
                     AFTVAKVTRLDILEDIRGALQQAVDEGKTDRWFRQELEPVLKRKGWWGPRDTTDPVTG
                     EPVTIQQGSPWRLDTIFRTNMSVLYSAGRWAEQMENVDDRPYWMYTGINDSHTRRSHL
                     ALHGLVLRWDDPFWQAFYPPNGWRCRCSVIALSAADVRARGLKVISSGSAMGQELKLV
                     SEKTGEMRNVATFNTGTTKVTTDVGWSYAPGAAYRPDLARYQGTLQPLAQQELRG"
     gene            45283..45741
                     /locus_tag="ROH59_001538"
     CDS             45283..45741
                     /locus_tag="ROH59_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000135514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HDX4804045.1"
                     /translation="MASDNLVSITINDKSLRRSLRALDLAATDLEPAMRKIAGTLLAE
                     TQFNFLDEGRPGWMPSLAAEERDGQTLQDTGRLMGSVSTDHDDRQAVVGTNVVYGAIH
                     QFGGKTGRNESVELPARPFLPVTGDGELQPEVVIPILDTIVRHLESAARR"
     gene            45956..47071
                     /locus_tag="ROH59_001539"
     CDS             45956..47071
                     /locus_tag="ROH59_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDX4804046.1"
                     /translation="MSAIHIFKAGTHTDMHGKKLPFTPDDLAACVKAYDPSVHEAPLV
                     IGHPRTEDPAWGWVKALSLSGVDLMAEPAQLDPQFAEMVTDGRFKKVSASFYLPDSPS
                     NPKPGVLYLRHVGFLGAQPPSVKGLKQVSFSEQEEGVVEFADWQAITNASLWGKLRDF
                     LIARFSLDEAEKVLPEWQLNSLREEAYRDTLSQDAAGAQFSETGPGPSSASNEESSMT
                     KEEIEALQEENRRLKQQAADRDARDAQVRQEQLHKDNVAFAEKLVAEGRLAPRASSVV
                     VALLDAVAGGDKPVEFAEGESRTPLATAFRSLLSDGEPVMNFAEQATKERVGDTVKVD
                     VAEFAEADPERLALHQKAVALSKKEGISYEAAVARCL"
     gene            47086..48039
                     /locus_tag="ROH59_001540"
     CDS             47086..48039
                     /locus_tag="ROH59_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804047.1"
                     /translation="MSDYLKGKRVVDPVLTSIARGYKNAAFIGERIFPVVLTDKEGVR
                     VPTFGKTAFVEYDTERAVGADSNVLVREKTGTLDLVLGEHDLAAPVDYREQAESMFNE
                     ESKAIRRATNGVNLRRELIAARLAQDEKVYRTGHVKKLTASDRWAGGKGDPIGVIEAG
                     MEAVRTATGLRPNLMTMGAGVMALLKFHPAIQAAIGANERKRITTEILQDLFQIEEIV
                     IGAPVSLPSMKAAMDKNSVPADIWGDNLMLHYVGKPQPGADSADENEPSFGYTLRRKG
                     MPVADKYDGAGGKVKYCRYTDIYKVAVVGGDAGYLITGISK"
     gene            48049..48387
                     /locus_tag="ROH59_001541"
     CDS             48049..48387
                     /locus_tag="ROH59_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HDX4804048.1"
                     /translation="MGTTQQVILITTVTAGAALAQQRFVGADNTPCKAGAAALGVAEV
                     DAVTGDSTPVSVLGIIAVEAGAAVSRGVAVQSDAQARAVPQSGDGKSCGIALDEAGGE
                     GDVIRILRGV"
     gene            48389..48835
                     /locus_tag="ROH59_001542"
     CDS             48389..48835
                     /locus_tag="ROH59_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1320 domain-containing protein"
                     /protein_id="HDX4804049.1"
                     /translation="MYCTLEDLLAQVPERTLIELTSEEMDFDSPATVNTRVVDSCIRY
                     ADELIDAHLRGRYILPLAEIPTVLRDIAITLVRYRLYARRPEGDLPDTVKDDHKEALR
                     QLRELRDNRLTLGLPSTQKDVPEPGEFRVRSRPATFGGRDGLLEKY"
     gene            48835..49299
                     /locus_tag="ROH59_001543"
     CDS             48835..49299
                     /locus_tag="ROH59_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gp37 family protein"
                     /protein_id="HDX4804050.1"
                     /translation="MNVLPVLDAVLARLREKLPQLQVEYFPEKPAEYRLNHPVGALLL
                     SYAGSRFDRPDDTGAVIQSQTIQLCVTVVFRQLNGKKGAINVLDAVRRILGGHTPPGC
                     RRRIWLTREVFIGEVRGLWQYALDFATESVFIEDSDLPSGPLLTEVNYEESE"
     gene            49299..49550
                     /locus_tag="ROH59_001544"
     CDS             49299..49550
                     /locus_tag="ROH59_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804051.1"
                     /translation="MKEYRYSGPASGVTLSDGTEILLWPGKTVSLPEEHDYVKVLVAL
                     KHLTPVPEETKPAGTPAVQSPKRRSSSDSEVKTEDTHGS"
     gene            49540..50967
                     /locus_tag="ROH59_001545"
     CDS             49540..50967
                     /locus_tag="ROH59_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001702162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDX4804052.1"
                     /translation="MAANYLHGPETIEVENGARPVKTVKSAVIGLIGTAPMGDVNTLV
                     QCLSEKDAAAFGSQFTGFTIPQALDAIYDHGAGTVLVINVLDPAKHKTAIEDEVVTFD
                     KSTGQARLAHPVVANVVVKNSEGSTTHTANTDYRVDAQAGVLTNLGKAIEAGGSVKVS
                     YEYADPSKVTAADIIGGVNSAGNRTGMKLLNDSFNLYGYFAKILIAPVFCTQKSVAVE
                     LIAMAEKLGAVTYIDAPVGTTFAQALAGRGPEGTINFNTSSDRVRLCYPHVKVYDPVT
                     NTERLEPLSQRAAGLRARVDLDKGYWWSSSNQEILGITGVERQLSAMIDDPQSEVNLL
                     NEQGITTVFSSYGSGLRLWGNRTAAWPTVTHMRNFENVRRTGDVINESIRYFSQQYID
                     MPITQALIDALTESVNAYGRKMTGDGAVLGFRCWFDPARNPETELAAGHLLLSYKYTP
                     PPPLERLTFETEITSEYLLTLKGGN"
     gene            50964..51488
                     /locus_tag="ROH59_001546"
     CDS             50964..51488
                     /locus_tag="ROH59_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HDX4804053.1"
                     /translation="MMSKIEINRITNANIYLDGTNLLGRAEEVKLPDVSMIMQEHKAL
                     GMVGKVELPAGFDKLEGEIKWNSFYRDAMLSAANPYRSLALQCRSSVQRYSSQGLIDE
                     IPLVTFLTIMFKKNPLGTFKQHENAEFSSSFTCTYIRQVLDGEELLQLDYLANIFRVG
                     GVDQLTDYRINIGG"
     gene            51491..51772
                     /locus_tag="ROH59_001547"
     CDS             51491..51772
                     /locus_tag="ROH59_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804054.1"
                     /translation="MSVELTDKGGRCAALGMSNGTWFTLLDIPGVETLFNTRKTNDPI
                     DCTRSKARKLADLIEAWEPPDHWFSGIGKSEGKTLLIAFLRNCKGFRTC"
     gene            51870..52205
                     /locus_tag="ROH59_001548"
     CDS             51870..52205
                     /locus_tag="ROH59_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HDX4804055.1"
                     /translation="MSQTPSDTFKLSYPFTTAAGTRIELVELKRLTVKDLKQVRKISK
                     NPADWDEPLIARSTGLLPEDLDNMDLADYLQLQKRFQLITGMGESNQGADAGAGAAGE
                     MVPVSAGGD"
     gene            52129..52287
                     /locus_tag="ROH59_001549"
     CDS             52129..52287
                     /locus_tag="ROH59_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HDX4804056.1"
                     /translation="MRATRALTQAQGLLARWFRFQPGEIDALDTDDLEMWLEQAEEQI
                     KSEYGDKS"
     gene            52363..55314
                     /locus_tag="ROH59_001550"
     CDS             52363..55314
                     /locus_tag="ROH59_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001705208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDX4804057.1"
                     /translation="MSGQFSVGVVIGGMIGSTFRSAMSGTRRALDSLSDTSRRLQERQ
                     NALTRATERYGQLGSSRMQHLNSELLRVSRTMEQIERQQRRLSAASATSDALKANRMA
                     LYGQGIEAYGMAQTVYHTVSPAVQQSMSFQDKMIDMSITAKYDNKTRDALAGQIKGWA
                     LKYNQYQDELQEAMGSLISDNIDNVSDIGFLMPDIARAATATRTSAQDWAKVAAVWQN
                     SLKGAARDFGAVQNIMAYAGDQGSFEIPDQVKWMQSLAPMMAGIASGKEAVAEIGASL
                     QIAKIGAGSTDEAANNFKNFLTKIFARDTQKQFADLGIDLQGSIASYKAAGISPIEGM
                     LSVIERYLNAKSPEALAGFKSAMKIKNDTARDEALQALAKNFGLGDMFADMQVMAFIR
                     PMLANMDRYREIRAGALRAADNDLLASAYDQRLKSPLEATKTLMVSSRDLAITLGDQL
                     APSFISLTQDLLPLIQGTKHWVATHPQFVSGAFKLISALLAIKIATVGLKLGLNLLIS
                     PFVNVWKTAVLLRTNWHRLTTALGEGGKLRWLVTGFSRLTSGGLKLSKVLAGSLVRGF
                     MSAARAVLWIGRALMMNPIGLVITAVAAAAYLIYRNWGAVSGWFKQRWADIQEAFNGG
                     IAGTGKLLINWSPAGLLYKAFAAALKYFGVTLPAKFTDFGGHLIDGLINGIKNKWGSL
                     KSSVTGMGDSISSWFKQCWADIQEAFNGGIAGTGKLLINWSPAGLLYKAFAAALKYLG
                     VDLPAKFTDFGGHLVDGLINGIKNKWESLKSSVTGMGDSISGWFSEKLGIHSPSRVFM
                     GFGDNIAQGAAIGLQRTTPLAALAGQRMASELLPRMPVSIQGPEIRDNTSGVRFSMPL
                     PDINGFMSSAKNAIGAVINSLSSMPAIPLSTRASILPGQRLANEMTPDVPRIPSPEIL
                     AAGYSGRGAAATGGGTSGGIQVSFNPQFFLNGRETTAPAGLTGALNMSLHELEKMLER
                     LLAQKQRKEYR"
     gene            55314..56198
                     /locus_tag="ROH59_001551"
     CDS             55314..56198
                     /locus_tag="ROH59_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001423226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4804058.1"
                     /translation="MFAVLGDIEFELITYWDGFEATFGVDYAEHARIGGKPGLQFVGD
                     RLDEIQITLVFHQHYCVPDVELARLRTAMKAHQALALVFGNGDYRGWFVITDVTATSE
                     QTDSTGNVLAVSATVSLREYTGDPKNPLQPPAIRTKLPGVGAVSGAIPSPSGVAQFIR
                     NGVNYAKQAQSVLQTTISAVRVTQKMKDNPVVALTRVPGLMSGLGNISGALGKSVPAF
                     NALSESMPDAISLARTASEAATYVQQAQSALSGVDKRNIAGALDTVSGQLNAVGTAFN
                     RMSPGLSAMAARILTRSV"
     gene            56198..56410
                     /locus_tag="ROH59_001552"
     CDS             56198..56410
                     /locus_tag="ROH59_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HDX4804059.1"
                     /translation="MFLEHVTRDGERWDSLAWQYYGDPLGYPRIIAANPHVAITPVLP
                     SGLLLLIPVIEAEEARTEEDIAPWLR"
     gene            56398..57552
                     /locus_tag="ROH59_001553"
     CDS             56398..57552
                     /locus_tag="ROH59_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HDX4804060.1"
                     /translation="MAEINSTAQVTSALTGVSDVLTPVFTLWYLQKNITSDIAPYVTR
                     VTWSDNIKNESDTIEVELDDTDGRWLDKWYPGKGDTLTLKMGYQGEKLLSCGTFSIDE
                     IEVSSPASVVSIRGVATSVNSALRTKTSRGFENTTLAAVAGRIARKHRLKLVGSIESI
                     RIDRVTQYAETDVGFLRRLASEYGYAVKVVSDQLIFSHLATLRSQEPVRQLKPQDVAR
                     FSLRDTINRVYKSAKVKHQKSSSKKLIVYEADGGTRESDKKLKGGKVTSADSLKVNSR
                     VSDPDSARIKADSALARHNEYQQNGSLTLTGTPQLTAGNKIELVSFGQLSGPWLITTA
                     RHAFDRNSGYTTELEVARGPVTRGKKQKTQKLTVYHPDGSTSTVIKEKKK"
     gene            57549..58145
                     /locus_tag="ROH59_001554"
     CDS             57549..58145
                     /locus_tag="ROH59_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HDX4804061.1"
                     /translation="MTGVTRQVGTVSAVDADRVQARVRLPECDNLRTNWLNVLQRNTQ
                     DNKDYWLPDVGEQVEVLLDANGEDGVILGAVYSDVDKPPFSDKNIRGTRFADGAEYSY
                     NRKTHTLIIRGGIEHIVIECGADVVLKTQKATIDAPETELTGDLRVRGKLIYEGGMAG
                     SGGEGVTATIHGNIEIKGNVHATGSMLSDGENSSHHSH"
     gene            58200..58547
                     /locus_tag="ROH59_001555"
     CDS             58200..58547
                     /locus_tag="ROH59_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HDX4804062.1"
                     /translation="MKTTSVFWQPALQAPGEIVRGLDDIRQAIQIILRTPRGSDPHRP
                     EFGSNLHLYIDWPVDRAIPHVVRESVDAIRRWEPRCQLMSVKPAVDGEHLTLRVSWKG
                     SDGQTRTQELLWR"
     gene            58538..59641
                     /locus_tag="ROH59_001556"
     CDS             58538..59641
                     /locus_tag="ROH59_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012905229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDX4804063.1"
                     /translation="MALTEPDFIERDADKITAEMIAKYEADTGKTLYPAQAERLLIDL
                     WAYREMLVRVAVQEAAKQNLVAFAREPMIDYLGELVGVYRLAAQPATTTLQFSVDEAL
                     AIDVLIPAGTRVSASDSVIFATDTDVVLKAGLLLVNVTATCTEPGTAGNGWQPAQVSQ
                     LLDEIDNVNLLVSNLMASSGGSEQEDDDRLRERIRLAPESFTNAGSRGAYRFHAMQAH
                     PNIVDVAVLSPVPGTVDLYPLLSTGLPDGGVLTLVESFCSDEKVRPLTDTVRAKTPVK
                     VDYTIEARITIYRDQDARSVKDAANSAIQNWVASRAATLGRDIVPSQIISALSVSGVY
                     QVELVTPALRVVAENEWANCTAITLNMTGVSDD"
     gene            59634..60212
                     /locus_tag="ROH59_001557"
     CDS             59634..60212
                     /locus_tag="ROH59_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HDX4804064.1"
                     /translation="MTEPLQLPPPLEGDISLRTLGRLAGRLDNIDLSVLMVFLVDIVD
                     SSALPWLGEQFSLSGDGWELAESDDVRRMLIKAAIELHRYKGTPWSIREVIRRFGFGE
                     VDLIEGTGRLSYDGNRSYNGLFVHGDAAAWAVYRVILKQPITNDQAAMLRQTLAAFAP
                     ARCHLASLEYQSVAIRYNNTAIHDGSYNHGSS"
     gene            60215..>61083
                     /locus_tag="ROH59_001558"
     CDS             60215..>61083
                     /locus_tag="ROH59_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HDX4804065.1"
                     /translation="MGNLNETEKWEENIYQLETSDPVLGGADGISNRAPRQLANRTKW
                     LKKKTEEAAQSLAEHVRSRNHPDATLTAKGFTQLSSATNSTSETLAATPKAVKAAYDL
                     AAGKAPASHTHPWSQITGVPAASLTAKGTVQLSSATDSQSETEAATPKAVKAAYDLAA
                     GKAPVSHTHPWSQITGVPAASLTAKGTVQLSSAINSTSEILAATPKAVKAAYDLANGK
                     QPADATLTALAGLATAADRLPYFTGADRAELATLTAIGRAIIAKGSIKDVLNYLGLGE
                     GSALPVGVPVPWPT"
BASE COUNT        14005 a        16475 c        16238 g        14365 t
ORIGIN      
        1 tgtcacacat tttttctttt tgaaaccaaa tctttatctt tgtagcactt tcacggtagc
       61 gaaacgttag tttgaatgga aagatgcctg cagacacata aagacaccaa actctcatca
      121 atagttccgt aaatttttat tgacagaact tattgacggc agtggcaggt gtcataaaaa
      181 aaaccatgag ggtaataaat aatgatgaag cgcaatattc tggcagtgat cgtccctgct
      241 ctgttagtag caggtactgc aaacgctgca gaaatctata acaaagatgg caacaaagta
      301 gatctgtacg gtaaagctgt cggtctgcat tatttctcca agggtaacgg tgaagacagt
      361 tacggtggca atggcgacat gacctatgcc cgtcttggtt ttaaagggga aactcaaatc
      421 aattccgatc tgaccggtta tggtcagtgg gaatataact tccaggataa caactctgaa
      481 ggcgctgacg ctcaaactgg taacaaaacg cgtctggcat tcgcgggtct taaatacgct
      541 gacgttggtt ctttcgatta cggccgtaac tacggtgtgg tttatgatgc actgggttac
      601 accgatatgc tgccagaatt tggtggtgat actgcataca gcgatgactt cttcgttggt
      661 cgtgttggcg gcgttgctac ctatcgtaac tccaacttct ttggtctggt tgatggtctg
      721 aactttgctg ttcagtacct gggtaaaaac gagcgtgaca ctgcacgccg ctctaacggc
      781 gacggtgttg gcggttctat cagctacgaa tacgaaggct ttggtatcgt tggtgcttat
      841 ggtgccgctg accgtaccaa cctgcaggaa gagtctcccc ttggcaaagg caaaaaagct
      901 gaacagtggg ctactggtct gaagtatgac gcgaacaaca tctacctggc agcgaactac
      961 ggtgaaaccc gtaacgctac gccgatcact aacaaattta caaacaccag cggcttcgcc
     1021 aacaaaacgc aagacgttct gttagttgcg caataccagt tcgatttcgg tctgcgtccg
     1081 tccatcgctt acactaaatc taaagcgaaa gacgtagacg gtatcggtga tgttgatctg
     1141 gtgaactact ttgaagtggg cgcaacctac tacttcaaca aaaacatgtc cacctatgtt
     1201 gactacatca tcaaccagat cgattctgac aacaagttgg gcgtaggttc cgacgatacc
     1261 gttgctgtgg gtatcgttta ccagttctaa tagcacacct ctttgttaaa tgccgaaaaa
     1321 acaggacttt ggtcctgttt tttttatgcc ttccagagca atctcacgtc ttgcaaaaac
     1381 agcctgcgtt ttcatcagta atagttggaa ttttgtaaat ctcccgttac cctgatagcg
     1441 gacttccctt ctgtaaccat aatggaacct cgtcatgttt gagaacatta ccgccgctcc
     1501 tgccgacccg attctgggcc tggccgatct gtttcgtgcc gatgaacgtc ccggcaaaat
     1561 taacctcggg attggtgtct ataaagatga gacgggtaaa accccggtac tgaccagcgt
     1621 gaaaaaggct gaacagtatc tgctcgaaaa tgaaaccacc aaaaattacc tcggcattga
     1681 cggcatccct gaatttggtc gctgcactca ggaactgctg tttggtaaag gtagcgccct
     1741 gatcaatgac aaacgtgctc gcacggcaca gactccgggt ggcactggcg cactacgcgt
     1801 ggctgccgat ttcctggcaa aaaataccag cgttaagcgt gtgtgggtga gcaacccaag
     1861 ctggccgaac cataagagcg tctttaactc tgcaggtctg gaagttcgtg aatacgctta
     1921 ttatgatgcg gaaaatcaca ctcttgactt cgatgcactg attaacagcc tgaacgaagc
     1981 ccaggctggc gacgtagtgc tgttccatgg ctgctgccat aacccaaccg gcatcgaccc
     2041 tacgctggaa caatggcaga cactggcaca actctccgtt gagaaaggct ggttaccgct
     2101 gtttgacttc gcttaccagg gttttgctcg gggtctggaa gaagatgctg aaggactgcg
     2161 cgctttcgcg gctctgcata aggagctgat tgttgccagt tcctactcta aaaactttgg
     2221 cctgtacaac gagcgtgttg gcgcttgtac tctggttgct gctgacagtg aaactgttga
     2281 acgtgcattc agccaaatga aagcggcgat tcgtgctaac tactctaacc caccagcaca
     2341 cggcgcttct gttgttgcca ccatcctgag caacgatgcg ttacgtgcga tttgggaaca
     2401 agaactgact gatatgcgcc agcgtattca gcgtatgcgt cagttgttcg tcaatacgct
     2461 gcaggaaaaa ggcgcaaatc gcgacttcag ctttatcatc aaacagaacg gcatgttctc
     2521 cttcagtggc ctgacaaaag aacaagtgct gcgtctgcgc gaagagtttg gcgtatatgc
     2581 tgttgcttct ggtcgcgtaa acgtggccgg gatgacacca gataacatgg caccgctgtg
     2641 cgaagcgatt gtggcagtgc tgtaagcgtt aaaaccgatg aagcccgctt gaaagcgggc
     2701 ttttttatgc gcctttacca gacaggcatt tcgtcttgca agaagggatt atgcaggcgc
     2761 tcataaccga gagtggataa tggtccgtga cccggaataa atgtcacgtc atcccccagt
     2821 ggcagcaatt tatctttgat tgaagaaatc agttgattgt gatcgccacg cgggaaatca
     2881 ctgcgcccta ctccgccttt gaaaataaca tcgccagaaa tgagcagcct tgcctgctca
     2941 ttaaaaaaca ccacatgacc cggcgtatgc ccggggcaat gtaacacctg taaagtcaca
     3001 ttccctatgc tgatggtatc gccttcgttc agccaacgat ctggcgtcag cggctggcac
     3061 tcttccagac caaacatacg actttgcgca ggcaagcctt gcagccagaa ctcatcttct
     3121 ttttccgggc caaaaaccgg cacgccgtaa tgttgcgcca gttccgccgc tgcgccaacg
     3181 tggtccagat gaccatgagt cagcaggatc tgcatcagtg tcaggccgct ggcatcaact
     3241 tcctgtttga ttttttccgc atcgccgcca ggatcgacca gtgcggccag acgggtttgt
     3301 tcacaccaga tcaatgaaca gttctgggag aatgcggtga ccggaataat acgatagttc
     3361 atactgcccc tgtttcgtta agcgattact accagtgccg tgctggcccg gtatcaatat
     3421 gcacaaagtt actacgtggg taatatccta caccacctgc gcgcatagat aacgcggctt
     3481 tgcgaatatt gcttaacgcg ataccttcaa tgtggaaatc catcgcctgg cctttggtgt
     3541 gatagctttt cttcgctact ccacggctgc gggcgcgtag ttcattgttg gtatcaatgg
     3601 aacgataacc ggaaatgagt tgcaccggtt tgcgggtgcc taacaaccct tgcaggcgat
     3661 acaactggtc gaataatcct gggtcgatgg actttatttt gttcgcgcgg taatcgcgga
     3721 aaaaatggtt aagttttgcc aattcttcct gaatatagcc tctgccatcg aaaaactccg
     3781 ctttgattga ctctccggta tgaagattat tgagtgtcaa aatgcgcggg cgtggggtag
     3841 agagtgttgc aaacgccggg gtcggcagga tggcggcacc gagtgcaacg ccaccaagcg
     3901 ccagcagttt gcggcgatta gcgtcgaatt tgtccatgat aatcaagtct acaggtcaat
     3961 gttatcgttt atatgcactt ctggcgcaca agaggcacct taaccgcccg taaagaagac
     4021 gtcaagatga ctcaacccca gcagtgacgg gggctgcaga gaatcgcccc cgatcatgct
     4081 aattattacg acaactgatt tccccgaact gcttcattta cctgattaat tgttccgctt
     4141 tcgatacaat ttgcgagctg gatcgcgcag gcagatcata attgtaaata tctgtacgat
     4201 actgggtacg accatcagca ccaacaaagg ccgtcagata gtagagattc accggaatcg
     4261 actgccgaat attgacgtaa cgcgtatcgc cctgcttcag cgcatcagaa atacgtttgt
     4321 cattccatcc tgcatcctgc aacagcatat tcgccagatc ggaagcttta ttcactcgta
     4381 cacagcctga gctcaatgcg cgtgtatcac gtttgaacag attgtggttc ggcgtgtcat
     4441 gcaaataaat ggcctctgaa ctcggcatat tgaatttata gcgccccagc gagttccgtg
     4501 ggcctggagc ctgctggaaa cggaacggta aattcgaggc cgtgattgta gaccagtcaa
     4561 cctgccatgg gtcaatcgct tctctgctgt tccagccgcg catcaccgta tagccatggc
     4621 tttcgagata tcccggatcg ttgcgcactt tcggcagaat atctttgcgt gccagagttg
     4681 gtggtacgtt ccacggcggg tttaccacta cgttgttaag tgcactgctc atcatcggcg
     4741 ttttgcgatc ggggcgaccg acaatgactc gcgaatccag cacctgattg ccgttctgat
     4801 agtagaccag cgaataggct ggaatgttaa ccatgatccc ggtagaaagc tctgttggca
     4861 gcaagcgcaa tcgctggatg ttgagtgcca acacgccagc acgctgggcg ggcgttacgt
     4921 ttaaccagtc acgcgttgcc gggccaatag caccatctgc tcccaatcct tgccatgcct
     4981 gaaaacgttt aacggcttcc accagttcat tatcgtaggc ggcgcgaacg gcaggcgcag
     5041 gtttactacg agacgtagtt tgtttgtcca tcagcttagt ttctgctgtt tcaacagtaa
     5101 cagccgatgg gctgactacc gcgtcagttg gcgtgtcatc gccaggtagc gtaattttcg
     5161 gtcccccgtc caacatgcct gtacgttgca atatttcgcg caacgccggt acgtcgttac
     5221 tccactgtcc tgggcgcaac gttgctttac cggtcagttg aggccacggt ttggtgtcac
     5281 tgagtaaggc cagtaacgat tcatgcatcg ccgcatattg cggatgctgc ggtgccagtc
     5341 ctgcaacaaa cgtcggcaat tgacctttat ccagcgccag ctgccattgg ttaatcaccg
     5401 aaagcggcgg cgttgcaagc gcataaggtt tactgctata tagccagcga gtgcctttga
     5461 ccggaatatt tgcaatgaaa tggagatagc ccatcatcgc atcagagagc accacgtcgc
     5521 gtgccatccc gttaacacca ggatcggtca gtaactctac ccatttatta aactgcggct
     5581 ggaaaccggc aatcgccacc tctgccagct gttgctggaa ggctttaaca gcatcacggt
     5641 tttcccacat gggttgcata tcgcgtgcgg catacaacaa ttgaagctgg ttaagataaa
     5701 ccggcttata acctgcgggt aattgagatt cgatttgcgt gcgggctttt tcagccgcac
     5761 cttcaggcaa tggctggatc cccgccatta ttgccgtggc ttgcgcctgc ggcagtgcct
     5821 cgccctgttc actgacagcc accgggctgt cgccagggat tacttcaggc tcatcggcct
     5881 gcgcattgaa cagtggagcg aatgttacgg ccaggcacaa actgattgcc gacagccgac
     5941 gaccacacat catattaagc aacatccctt gccccctgtt tttatcatac tctgaatagc
     6001 caggctgtta ttttacgact tgcctgtaca acgccaatac tcacgaaagt atgacgagca
     6061 agcctgttac tcatcaggct tatcttcagt atataaacgc cgatacgttt ttacataacc
     6121 taatgtaaag aagtttaaag aaaagcgcgc cgtaatgtgc cactttttta gtgcagaaac
     6181 ggagttttcg gaaaaagaaa aggcggcatt gctgccgcct taattttaac tcgcctgaga
     6241 aggcgcttcg tcacttcctg gaagcgtttc agggagttga ggcgcaaatc ctcgcaggcc
     6301 gacgacgtga acgtgttcgg tattctggaa gactttacgt accagtttat aggtggtgcc
     6361 tttctccggg ctgatatttt ccggcgctgc gataatgagc tgcatttgca aacgttcaca
     6421 caattcaaac agcgtggcga tggaacgggc gtccagtcgc gctgcttcat cgaggaacag
     6481 caggcggcaa ggagagatat ctttaccgcg caggcggcga gattcatctt cccagctttg
     6541 taccaccatc accagaatcg acataccggt accaatcgcc tcaccggtcg acaatgcacc
     6601 agactctgca cgcaaccagc catcggaacc acggttaacc tcaacttcca tttccagata
     6661 gttgcggtaa tccagcagtt cttcaccgat ggtctgcggc gtgcgctgcc ccatatcaat
     6721 ctgcgggtta agacgttgat acagtttcgc cagcgcttct gagaaggtca ggcggttgct
     6781 gttaaacaga tcctgatgct gctcgtgctg ttcagagagc acatccagca gcatggcgtg
     6841 cgtttcacgt acgttcacgt tcagacgtac gctgttcacc tggccaaacg atacgttctg
     6901 caacccctgg ttgagcatac ggatacggtt ctgctcgcgc tgaatggttt tgcgaatgat
     6961 gttcgccacg ctgcgggaac tgatcgccag tttctgttca cgagaggtta attcttcggt
     7021 cagacggcta agctcgatct ccatctgttc gatagcttcc accggatcat cggtacgaat
     7081 aatatcctga cgaatacgtt cacgcagatg ctgataaacc gccacgaaga actgaatttt
     7141 acgttccgga cgttttggat cttccgacat ccgcagcacg tcgcgcagat gttcgttatc
     7201 cgccaccgcc agacgcagcg cacctaacgc cttatccgac atggagcgca aatcatcagc
     7261 ggagagataa gccagctcac gacggtgtaa gcgacgctca acgccattat ctttcaccat
     7321 gcgcatcacc gcacaccagc ccgctttggc ggtcactacc tgctcgcgca tctcaaagta
     7381 atcccgctcc agcttgcgca gtttacgggt caggttgtcc atctccgctt cgcagaaggt
     7441 aagcgctttt tccagttgat tgcgtcgtga acggttattg ctcagttgcg cgtgcaactc
     7501 gtcacggcga atacgtgccc gctcttctgc cccgctatca gcacgcacgc cgatatcctg
     7561 caattcacgt tgcagatcgt taagtagctc ttttttggtg tcatacgaac ttttcagcga
     7621 agccagcacc tggttgtact gattcaactg cgctgcgtgt ccgcgcaacg cttcacgagc
     7681 gcgggtacgc tccgcttccg cctgttccag acgttcacgc agtttttcgt tgagatcgct
     7741 gttaccgcta agcatttctg ccgagtcaga gtagctaaag tgcgcacgac gctgcaccac
     7801 ttccgtcagg gcaaacgcct gctgacgggc atcgcgctgc atctgctgag agtacgcgta
     7861 atcttctttt aattgttcga actgttccgg gtcgctctgc aataccgaaa cgatcggctc
     7921 cagtttcgcc agttgattgc caaactgctg aacaaaacgc gcggcttcct gggcttcatc
     7981 cagacgttcg cggatttcat cgacgcgatc cgccaggctg tcatcagcca acaggttgag
     8041 acgcggcaga atgcggttca gcgccgtaac gccctctttc gcctgctcaa actgaatacg
     8101 ctgctgctgg ttatcatttt catgattact caacgcccgt tccagttcga cgcgacggct
     8161 gttcagttga cggatttctg cttccgggtc agactcaaac gccaccgcca gatgactgcc
     8221 gataaagcgg ctgaacgcct gatgcagacg ctgggttttc tgtacatcaa aggaaagcgt
     8281 ggcgaagcgt tcggaaagca cttcccgctc ggcatggagg ctttcaatac ggctttcacg
     8341 cgcagcacga ccaaacagcg gcacttccgg gaaacgtgaa taacgccact gacgatcggc
     8401 gattttcacc accaccgctt tttccagctc atcaacgctg aacacgctgt catcgaatga
     8461 ctgcggatcc ccttcgatca aatagagatc ttccgggcaa tcggtcaagc cttccaggtg
     8521 ttcggttacc tgtgacagat ctggcaccac gatggcgtgg cgtgacgggc catacagtgc
     8581 tgagaagtac ggcgcatctt ccaggctaac gtcgtcataa atttctgaca gcagcacacc
     8641 accaaaacgc tccgccagcg cgttcagacg ctgatcttca gaaccacctg gctggcttaa
     8701 acgttcgatc tcttcatcga cggcgttttt gcgcgcgcct acttcatcgc gttcaacaat
     8761 tgcctcgcgc tcacgctcca gcaactgttg cagaaattcg gtgacatcct ggctggaggt
     8821 gaactcttcg ccgcactgtt cgctcaactg gttgagactg ttttgcgctg ccagccaaac
     8881 cggcgcacgc tgcatcaaac tctgaatgcg agactgcagc tgttcctgct cctggcgcag
     8941 tgccatccgc tcttctcggg cgttagagac gctatcggaa agagaggcaa tgcgtgcttc
     9001 cagctcctga tgcagagctt ccagttcatc aatatcaaaa ttcttgccct gacgtttgca
     9061 gaaatctgcc agcagacgct cagcttcttg ctgctcacgc agacgctgtt ccagttcgct
     9121 taagcgcatc cgcaacggct gaacctgctc tgccaggtga cgctgatcga ccccttcgcg
     9181 caatagttcg cgagcgacat cccacgcctc gttacgcgcc agcgggccgt tgattgccac
     9241 caccagctga taagcctgct caaactggct gtgcgcggtt tgcgccatgc tcattttctg
     9301 ctcaagagag agcatttttt cggtcgcttc cagctctttc gcctggaagg tttccagcca
     9361 ttcggcagcg ctgtcggcgg ttaagtccgg cagatggcac agttctttgg cacgattaag
     9421 cgcagcaatc gcctggttat actggatcgc gcgcgtttgc tggacgtcca gcgcctgctg
     9481 gtagtcagca agctggcttt tcagctcgtc cacttccagt tcggcagctt ccgcacgagc
     9541 ctcgttctct tcctggcgtt cgatggcttc tgccaccact tcgttttgct cttccagacg
     9601 gatctgcagc tcatcgagat ccgcttcgta gcgttcgatc ttctcctgct gacgcagtgc
     9661 ggtttgcacc aggttcaggt gatcgctggc cgcctgataa tccgcttcca gatcgccttc
     9721 ggcaccgttg tgctcagcca gctctcgcgc catgtcgacg tgtttgtact gctcagccgc
     9781 cagttgctga cgcgaagtat gtagctcgcg acgaaactcc agggccttat cgagatgaac
     9841 acggcgctcg ttggcgtgac gcatgtagtc cgccgccacg tagttggtgg cttcgctgat
     9901 cagatgctta aacaggtcac ggtccgactg ggtgacacga atcgcttcca gcgtcatgcg
     9961 gttttcacgc agcgccgctt ccatgtcctg gaacgctttc cacaccccac tgttttccgg
    10021 caacaggtag tcgcgcagag aacgagtaat ggcgctggag atcccgccat acagcgaggc
    10081 ttcgatcaga cgatagaatt tactacggtc agacgctgag cgcagacgac gcgcgatgat
    10141 gcccagatcg aacatcagcg agtggtaatc ggtaatggag ttgaactgtt taaactgcac
    10201 gccttccatc gcctcgagct tgtctttcag ctcgttaagc ggcagcacgc gcgcctggcg
    10261 ttcgttcaga gtttcggtca ccagttgtgt cggctgcacc gacatcggca gtccctgaat
    10321 ggcaaacggc ttgatatcca ctttacgatc gcgtccggca acctgttgca gacgcacacc
    10381 gaccaccacg cgctggtgac gcgagttaat ggtgtcgagc atcgaataac agacacccgc
    10441 tttcagctta ccgtgcagac ctttatcgcg cgaaccgctg gtggccccgg cttccgtagt
    10501 gttacggaaa tgcagcaggg tcagatcggg gataagcgcc gtaacgaacg ccgccatggt
    10561 ggtggattta cccgccccgt taccgccaga aagcgtcgtg accagctcgt caaggtcaaa
    10621 agttcgggca aaaaagccgt tccagttaat cagcgtcagt gagcgaaatt taccgcgttc
    10681 aatcattatt cttcctctcc gctatctggc tgactctctt cggtttcatc gttgagttgc
    10741 agatgatttt caatcggcat tgcttcacca tcacgaatca ggcgacgctg tgcttcacgg
    10801 ggatcgtcgc cagcacgcac atcggcgccg aagcggaaca ccgattcggt aatgcggaac
    10861 ttgctgctgt cgtggcccat aaaccacacc atgcctaaac gacgcagacg gttgagcgaa
    10921 gaacgtactt tttcctgcaa cttctgacgg tcaacgtctg aaccggttga acggttgttc
    10981 accagtttca gcagtttcgc ttcatcggcc agggtgagca gttcgtcgta cagttcctgt
    11041 tgagtaaaaa tcccctcatt cgccagccgt tccgggctga gatagagata acagaggatt
    11101 ttcccgacca tcatatccag ttccgacaag acggaacgag ggatcagcgt ggtggaacgt
    11161 gggcgtagat agaagaaccc ttccggtgca cgaataagct caacgttata acgcgcgtaa
    11221 aactcttcca gatattcctg aaaatccatc aggaatgcat gattatccag ttcgtcgagg
    11281 ccaatatggc ggcctgaacg taaggcgcta tccagcgccg gaaataacgg attcgccagc
    11341 gcctgcgcca gcttaaccgg catcacttgt tcaatatttg tcgatgacat gcgcctgtac
    11401 cttggctccg taatcattaa tcggctgcca tttcgctggc agtccggtga aatctgcttg
    11461 cgctacgcca agacgtaccg cctgatcaat aacaatgcgc gcaacgtcaa agtgacgtgc
    11521 acgcggatac tgtgacagat attcgcgtac caccagacca agatccaacg gcacttgtct
    11581 ggttttgtac acggcaagtt gttcttcgat gatcgccgcc agctgttcgc ggatctcgtt
    11641 aaactcttcg tactccagat cctcaggaag ttccccagtc acttcttcat cgcgcagtac
    11701 catctcttcg tcacgcatat ccagcagacg atcggcattg gcataagtta gcgcccacgg
    11761 ctcatcaaaa taggtttgta ccgactgacg taaccgctga gcaaagacgc ggtttttatc
    11821 catatcgatc gcagtacgaa taaatttgtg tacgtggcgg tcgtagccaa tccacaagtc
    11881 gatggattgc tggccccaac tgataatacg gtcgagtttg ctctgaagat cgaacaccag
    11941 acgatcgaca aaatgcaggt cgtcatgggt catcgtcgca tcctgaatgc gtaacaggtt
    12001 ggcctgcaat ttatcgcctg ccgcttccag cgtatcctgc aattcacgca gcgttccgga
    12061 agtttctgaa agcaacaatt cacagctgga aatcgccgcc cgccagtctt tgttcaacaa
    12121 ctgggcgata tcatccttca cctgctgctg ctgttcatcc atcagacgtt gcgtcaggtc
    12181 gatactgtcg aaaatttctg ctaccgaata tttcagtggc gcataaacat tgcggtgcca
    12241 gtgaaattca tcaccgccct cttcggcggc atctgctgcg cgtttgagct cacccgccac
    12301 aatcgacaat tgcatagaaa ggcgcagcgt agaaaactcg cgctgacgaa tgtaatagtc
    12361 agtgatgccg atgccgagcg gcgtcagacg gtaaattgcg ttcccttccg cctgctcgct
    12421 ggtaaagcgg ttcagcagac gttgacgcac catgtcgttg atcgcgttgt tggcgcgcac
    12481 gccgatggtt tcgctggttt gctcaaacgc atcactcaca tggcggaatg catccaccag
    12541 ctcgccttca ctcatctcac catccagacg ctcgccgttc agcgtggcaa ccgccagcag
    12601 aaaagagagt cggtctaccg gcagcgagat ggagaagtca ttttttctgg cccaggcaac
    12661 cagttcgggg actgtctggg aaaattcact catactttat ccttgctctg cggtttgcgc
    12721 gcggtgacat gaatataacg ccccagggta atatacggtt cctgacggca ataacgcgtt
    12781 tctaattcaa gtaatgcttc atagcagtcg cgctgctggt gcttctcacg cagataatca
    12841 tgaaacacgc gaacgcctgt cttacccaga atttgccaac cagcttcttc cagccacaga
    12901 taaacctgcg ccgggtcgcg tggataatct ggcgaaagcg tccgtttttt ctttttcggc
    12961 attcccgcct gcacgtaatc aaaattcccg gcgaccatgt tatgcatcaa caaaccatgc
    13021 gcattgtaga acattaacga caacacgccg cctggacgca acactgacca cagggtctgt
    13081 aatacgctgc ggggatcggc cacccactcg agcaccgcat ggaacaatat cagatcaacg
    13141 ggcgtttcca aatgcgaagc aacatcctga gcggcgcaat gtataaattg catgttgtcg
    13201 ctcacacctt ttgcttctgc cgcctgtttt gcgcggtcga tcatctgcgc agaaagatcg
    13261 cataaaatga cctgatgccc gcgctcggcc attttgattg cggtctgccc ttctccaccg
    13321 ccagcatcca gcacacgcag tttttgcggg cctatttctg ccagcacgcg atcgagatcc
    13381 tgccacagaa tagcctgtcg aagctgccct ttggtggtgc cgtaaatgtt acgggaaaac
    13441 ttttccgcaa tatcatcaaa attgcgatcc tgcattgctt tctccaccgg ttggctaaga
    13501 cgttttctga taaagacgct attttgtcac agccacggcg agaatgaacc cgtctggtgt
    13561 aatatcgctg gcgatccctt gctatatggt taaaaaagga accagaaagg atgcttttta
    13621 cactgaaaaa agtgattggc aatatgttgc tgccacttcc gctaatgttg ttgattattg
    13681 gcgctggcct ggcgctgctg tggtttagcc gttttcaaaa aaccgggaag atttttatta
    13741 gcattgggtg gctggcgctc ttgttattga gtttgcaacc ggtagccgac cgcctgctgc
    13801 gtcccatcga aagcacctat ccgacatgga ataattcgca aaaagtggac tatatcgtgg
    13861 tgctcggagg tggttatacc tggaacccgc agtgggcgcc gagctctaat ttaatcaata
    13921 acagtctgcc acgcctgaat gaaggtattc gcttatggcg cgaaaatccg ggatcaaaac
    13981 tgatcttcac gggaggcgta gctaaaacca atacggtgag cacagccgaa gtcggtgcca
    14041 gagttgcgca atcgctgggc gtgccgcgcg agcaaattat caccctggat ttgccaaaag
    14101 ataccgaaga agaagctgca gcagtgaaac aggcgattgg tgacgcacct ttcctgctgg
    14161 tgacctccgc atcacatctg ccgcgggcga tgatcttttt tcagcaggaa gggttaaatc
    14221 cgctaccagc cccggcgaat cagttggcca tcgactcgcc gcttaatccg tgggaacggg
    14281 caatcccttc tccggtttgg ttgatgcata gcgaccgcgt tggctatgaa acgcttggcc
    14341 ggatctggca gtggctgaaa ggttcgtcag gcgagccacg gcaagagtga ttttgatgcc
    14401 agatcgaagt tacgccgatt aaatcgtccg gtgttgacca gttgcgcaac ttcatcccat
    14461 aacacataca accaacgccg ccagatgaac gactccgcca ctggcgcgcg ttgcagataa
    14521 ctccagagca aatcttccgc cagagaatta tccattagtc ggaacagttc gtattctcgc
    14581 ggtgcccaaa gcattagtcc cggtccgacc atcgccagta actgatcgct gcgcgaatct
    14641 ttcagcatgc tgcgtaaaca gaagttaccg tgaatcagta cacaattgtc gttaaagcct
    14701 tcaaataatg ccgggagaca ttcgcgagtg cgaaacagga tccgcttatc ctgcatcgat
    14761 agaccggtgt tattgaactg attgagcgtg gtccatagca cttcaacatg ttgccggtac
    14821 catgagggcc agaaattttc ctgagtattg tcgaccgcgc cgacgcaacc acgactgtcc
    14881 tgacggtgcc aggccagtaa ggcttcaacg atttggtctt tgagttgttc ccagcgttct
    14941 ggtgttcggg ctggtgcctc caccgaaaca ccacgcattc gctccagtag caggacatcg
    15001 gggccggggt gttcttcatg cgtcatcaca ccataaatag tcggcatacg gacagtccca
    15061 cttcttgcca gcatggtggt tttccatgcc agttgtcggg cttttccggg cgtactaaag
    15121 cttcttgcca ttaacggcat tgggtttccc tggctgtcat acaaagccca caacgccgta
    15181 tccgcttttt cattgacgca ctcaatacga ctgagttttt cgcccagtaa atggcttaat
    15241 tcggcacgca gctgttccat tcagattacc ctcataaaag ctactgcttt cataatgagc
    15301 gccaatataa aagatgtcac ctgaatgaga tcaattgttg aaaagaaaaa ttgaggaaaa
    15361 tcgtaacggt acgacactcc tcccaaaatt ggctggagtg tcgtgaagtg aaattagcgc
    15421 atttcagcgc gaacgcgctc gagatcttca ggggtatcca cacctgtgcc aggaacttcc
    15481 tgggcgacag caacgtggat tttttcgcca taccacagaa cacgaagctg ctctaacatt
    15541 tcgatatgtt ctaacggact tggctgccag gtaacataac gacggataaa gcctgctcgg
    15601 tagccataaa taccaagatg acgcaggaag ttatcgccaa cggtttcaag gtcttttgca
    15661 aaacgatcac gatcccacgg aatggtggcg cgagagaagt acagtgcgta cccttcggca
    15721 tcgagaacca ctttcaccgc attcgggtta aacgcttctt ccgcattgtg gattggcacc
    15781 gccagagtcg ccatacccac ctgacgctga gcgaggttat cagcaacctg acgaatgatt
    15841 gtcgcaggga tcatcggttc atcaccctgc acattaacga tcaccgtgtc gtcgctgaat
    15901 gcgcattttt cgacaacttc cgccaaacgt tctgtacctg actgatgatc ggcgcgcgtc
    15961 atacatactt cgccgccagc ggcttcaaca gcgcgggcaa catcctcatg atcggttgcc
    16021 acgatgatgc gctcggcacc tgattcgcgc gcgcgttcaa gaacatgaac aatcatgggt
    16081 ttgccgttaa tatcaaccaa tggtttaccg ggcagacgcg tggacgcgta acgcgcggga
    16141 ataatgacca caaaactcat gatttaccct catcagcagt cagcacgcgg gcttccgttt
    16201 ccagcaacac tggaatgcca tcgcgcagcg ggaaagccag gttgtccagt ttgcaaataa
    16261 gctcttgttt ttcctggtta taccaaagtt ttccgttgca aaccgggcag gcaatgattt
    16321 caagcagacg atgatccata gttcctccag atggatcggg ttatgaatgc ataaatctta
    16381 tcataatcat ttatgcgacg gggtctattt cccagccggc gcggcaatca gtaaagaggc
    16441 cttgcgagca gcgtcctaat gtcacccgcg ttgcctgctg ccagttagcg aaatcagtaa
    16501 tcgcctgacg taaccctttt tgcagcgttg tcgttggttt aatgccttcc tgtaaccaca
    16561 gagagataac ttcaaggatg cctttctggc gatgcatttt ggaatccatt cgcccaacta
    16621 attgcccacg atgtaataac ggcagaacaa aatagccata ctggcgtttc ggcgctgggg
    16681 tatagcactc cagccggtag ctaaaatcaa aaagctgctc cgcgcgtttg cgatcccaga
    16741 caacaggatc aaaaggcgaa agtaccgcgc tgtgcgttgc agtgagcttt ccggcgagcg
    16801 cacgctcgag tagcggcagc aaatcagcat gcagccaaag attgcccaat ttttcaacat
    16861 gcacagcaat gatttgctgc tgttcagccc tcgcttcacg ccacgccgcc agtgccggac
    16921 gttttagccg gtagtaatct gccagccact gttcgcgaaa tattcccagg ctacgcgcac
    16981 tgttatccag catgatgatt tctgcttctg cttgcgaaac gagatcgcgc tcatcatccc
    17041 agtcaggcat gacacggtgg gttaaatcat aaacgcgctg gaagttgcgc cgttcaatca
    17101 ccatcacctt tccggcagta aataaacctt ccagatgtcg tttatgcggc ttccactccc
    17161 accagccgct tgcaccttta cgaggatgct caaaatcggc tgaacgtacc ggccccctat
    17221 catgaatatg ctgaattaac agtgcaattt ccgccgcatg ttcctgcatc caggcgtctt
    17281 tatatttcca gcccattttt tcaggtgcca gcatgcggtg gcgaataaga cgaaaatcgc
    17341 tacgcggcat aaagcaggct tcatgcgccc agtattccat taattcgcca cgcgccagag
    17401 actcatccag ccactgggca ggataatttc ccagacgact gaaaagcacc agatatgggc
    17461 tacgggcaac aatattgatg gtatcgattt gcagcaagga catgcgggag atcgttgccg
    17521 gaatatcctc caacgacgct cgacggtggg gtttgtttaa caggccttgt gcagcgagat
    17581 gaagattacg cgcatcagca agggagaggt gcggcagaga cattcatgac tccatcaatc
    17641 gaacgctgcc gcggcgtaac tagttgccag aagccagcga agttagttgc gcaagcagtt
    17701 tcgctggttc atcacctgaa agctgtgcgt ctacaggcaa ataccaccaa ttttcttctg
    17761 caaaggcccg gcatttcacc gcatcttttt cagtcattac cagcgtttgt ccggcgctta
    17821 ccaacgcgct gacatccgca tgattcaaaa actgatgatc ggccagcggt acacattttt
    17881 cgggttgtac gccacacatc ttcagcgtgg caaaaaagcg cggcggatgc ccaatccccg
    17941 caatcgccac cacatgttca agctgagcaa cgtcacaacg tgtaccggta cgtaaattca
    18001 ccgcctgacc cggcagcaga tgcatgggga tttcaccgct gcgggggaca ccgccgttga
    18061 cgattaccgc atcaaccaac tttaagcgcc ctgctcgctc acgcattggc cccgccggca
    18121 accaccagcc attgccaaag cgacgcacac catcaataac gacaatttcc acatcacgcg
    18181 ccagacgata atgctgtaaa ccatcgtcag ttacgatgat ctgcacatca gggtgttgcg
    18241 ccagaatggc ttttaccgcg tcagaacgca cgggagaaac cgcaacaggc gcgccagtgc
    18301 gttgataaat caacacaggc tcatcacccg cctgtgctgt ggtggtatct gccgacaata
    18361 acagcggata agattcagcc ttaccaccat atccccgcga tacgaccccc acgcgaatac
    18421 cgcgctgttg cagctgttcc accagccaga caacgaccgg ggtttttccg ttgccgcctg
    18481 cagtgagatt tccaaccacg acaaccggta cgggggcacg ccaggcgcgc ttcagtttta
    18541 gtttatagca aagacggatc gcgccactca ccaggccata caaccaggag agtggcagca
    18601 atagccgcca taaaggggac tcaccagacc agattttttc gatcattggc caaactgcat
    18661 tttgtgaagt tgcgcgtaaa cgccacggtg ctcaagcaaa tcgttatgcg taccgcgttc
    18721 cacaatgaca ccatcctcga caaccacgat ttcgtctgcc ttttcaatgg tagacaagcg
    18781 gtgggcaatc accagagagg tacggttttt ctgcaactca tccagtgctg cctgaatcgc
    18841 acgttcggat tcggtatcca acgccgaggt agcttcgtcc agaatcagta tcgggctatc
    18901 acgcaacaag gctcgagcga tagcaatacg ctgacgctga ccgccagaga gcaacacgcc
    18961 gttttcacca atgactgtat cgagaccgtt atccatctta ttgatgaagt ccatggcgta
    19021 ggccatacgc gcagcttctt caatttgctc acggctgtac tgttcagtcc ttgcgtaagc
    19081 aatgttgttg gcaaccgtat cgttaaacag atggacattc tgcgacacca gagcaacctg
    19141 gttacgtaac gacgccaggg tatactcgcg cagatcgtga ccatccatca ggatttcgcc
    19201 ttcatcaata tcgtaaaaac gtgtgattag gctggcgatg gttgatttac ctgaaccaga
    19261 gcggccaacc agagcaaccg tcttccctgc cggaattttc aggttgatgt tacgcaatgc
    19321 aggcacatca cgtcccggat aagtaaaggt gacattgcga aactccacgt cgccagtcgc
    19381 acgctcgatc acgcgcttac cttcgtcttt ctcctgctca ctgtccagaa tggtaaacag
    19441 cgtctgacaa gccgccatac cgcgctggaa ctgggcgtta acgttggtca gcgatttcag
    19501 cggacgcata agtgcaatca ttgaagagaa aacaacggta atcgtaccgg cagtcaggct
    19561 atccatgaca cttgggaagc ttgccgcata cagaacaaac gccagcgcca aagaggcgat
    19621 cagctgaatg atcggatcag agatggaaga ggctgaaacc attttcatcc cctgaagacg
    19681 cattcggttg ctgactttat cgaagcgttt cgtttccact tcctgaccac cgaaaatcaa
    19741 tacttcttta tggcctttca gcatttgttc ggcgctggtg gtcacctgcc ccatggtgtt
    19801 ctgcatgttt ttactgatgt tgcgaaaacg cttcgataca acgcgaatcg caatcgaaac
    19861 aatcggtgcc agcacaatca aaatgatcga cagttgccaa ctgtaataga acatcatgat
    19921 gaacaggccg atgatcgacg caccttcacg cacaacagta atcagtgcgc cggaagaaga
    19981 agaagcgacc tgttcggaat cgtaggtgat acgtgacaac agcgtacccg ttgactgttt
    20041 gtcaaagaat gaaaccggca ttcccatcat gtgaccaaac aggcggcgac gcatagtcat
    20101 taccaccttt cctgataccc aggagataca gtagctggag atatagctgg tgataccacg
    20161 taaaatcatc agcccgatca ccaccagcgg catccacatc agcacggagc gatctgtttt
    20221 accaaagcca tcatcaagaa gtggcttaag gagcgataac atgaaggtat cgctggctgc
    20281 gttgaggatt aacgctacgc ccgccacgat cagacccgct ttaaaaggcg caatggttgg
    20341 ccacagtcgg cggaacgtct gccacgtaga gagatctttg tcgttatgca ttcaaaaaac
    20401 cagcatttgt tgaaatagcc gcatattcta cccgttatcc actggcacgc caaaccactg
    20461 atgataccaa cgaggtaaaa tttgctctct gaggctgcta atccaccagc cttgcgctga
    20521 aaaattgacc gttatttgcc cctgatgtgg agtatcaagc cacttataac cctgttgatg
    20581 atagcgatat ttaactttgc ttgagggcag tcgccatgcg ttatagcgcg atgccgatgc
    20641 gagtgccact tttccattca ctcgctgaat taatggcaac gatgatgagg tattactgcc
    20701 atggtgaggt acctgaagta atgttgcctg catttgctgc cagtaacggc ttagcatctt
    20761 ttgttcagcg ggggcttcaa tatcaccggt tagaagaatg ctattcgtcc cgtcatcaat
    20821 cttaaccaca caggaatggt tatttccttt atcgttgcta ccttgtaaag gccagtgcgc
    20881 gctgaaacgc aatccttgcc attgccacgc ttcgccacgc acacagggct gatgatgttc
    20941 ccagtttaac ggacttcgga tccataacat cggccatgtg tgcaatattg agtccagccc
    21001 tccccggtga tccagatgtt catgactcaa aataacgcct tccggttcaa gattatgcca
    21061 gtggagccag gggataatca gttgttgccc actatcccct tcgggccagg ccagtcccgt
    21121 gtcatagaga atcgctttgc cgtttcgcgc aatgaccatt gccagcccct gcccgacatc
    21181 aagcatgtac acttgccact cgtcaggtcg aggtttttgc cacagcggca agcacatcag
    21241 caagcctaca gccacacaca ttgctggcaa cgttcgccag gcgtttaatc gccataccac
    21301 cagtaagaac catggggaaa atgttagcca ttgccaacgt tcagcaatgt tgatccaccc
    21361 ttccggcaaa ctctttaacc cccagaaaag taaagccaaa gaccggtcgg caagaaacca
    21421 taacccttgt tccagaataa acggcccgct taaatgcaca accatcgcgg cgagaatcaa
    21481 cggaaccgtg ataaatgtca ccaggggaat tgcaaaaaga tttgcaataa acgaggtcag
    21541 actaatgcca tgaaatatga caatttgcac gggcataagc aggagggtga ttcccagttg
    21601 cagatggatg agggaaacaa ccgcgcgcaa taccggcggc agctgccact ccggacaggg
    21661 aaaccactga taccaaaaaa tcagtgccgc gaccgcagcg gcagaaagcc ataaactttg
    21721 cgagagaatg gcaacaggat ccatcagcaa aattgccgcc agacaacata tccatacatc
    21781 ccagccactc cattgtcgtc cacttaactt aagcattccc caaatggcaa gcgccaccac
    21841 ggtacgcaat gcaggaggtt gcattcccgt aagccaggca taaaaagcag cacagcagat
    21901 tccaccaatt aatggcattt gccagtggag ccagcaccca ggcagaaaaa cttgcccacc
    21961 gcgaatgagt cctgcagcca gcaacgccgc aaaagcgatg tgcaatcctg atatcgccat
    22021 taaatgcgcc gttccagtat cacgcatgat atttttgatt tctttgggga cggataaccg
    22081 ttcccccata cctaatccaa gaataaccgc gttccacata tagggttgca gcgttgtttg
    22141 tagtgacgcc agatactgtg cacgcaggct acaattcggt tcaatgacac ttgcctgcag
    22201 aaaacggccg gtgagcggtt gatgctgggc aatggcataa cgctggctat caaagccgcc
    22261 atcattaagt tgaccatgaa ctgcacgaac tttgagtttc attgaccata cttgtccggc
    22321 acaaaccgct tgcggaagat attcgccata cagtacgagg cctggcgcag ggaatatacg
    22381 tcgaccttgt agatgagtaa tttgaccgta atgagtggtc atgccgtcag tagcaatgat
    22441 ctcaacaatt gcatcctgcg tcgcgccagt taaggtttct cctgcccaca aaatttgctt
    22501 tgctgctaat atgccccaaa cgaaaaacag caacgtcagc gcgatataac ggacggtttt
    22561 aacagggata aatgccagta cacaggcgaa gagagtcaga aacgcaaggg ttactgtccc
    22621 tggcaattgg ggcaaaatca gcaacggaaa aattccgcaa attatgcata cgccgactgt
    22681 cgttattttc atgcaccctc cctgtttata gaaagtgtgc aactttgttg aacggttgtc
    22741 tggtgggagt tttgcgttcc ccgaggcacg ttcagaagaa tttaacgata gggtgaaaac
    22801 tgctcaaaac tctgcgaggc agcttccagt tccagattag agaaatgaaa aaagcacccg
    22861 acaggtgctt ttctcgcgtt caagtttgag taaaaactta accgtaaata ttggcgcgat
    22921 cgcgcagttc tttacctggt ttaaagtgag gaacgtattt tccttccagt tctactttat
    22981 cgccagtctt cggattacgt ccggtacgtg gtgcgcggta gtgcaaagag aaactgccga
    23041 aaccgcggat ttcaatacgc tcgccctgcg caagagtcga ggccatatgc tccagcatct
    23101 cttttactgc atcttcaacc gtcttggcgg gaatgtgcga ttgctgggtg gcaagtcttt
    23161 ctatcaattc tgacttggtc atgattcctc cggttcctta aaggcaaatt aagcggctgc
    23221 tgttgctaca ttgattaagg gcggccgtag ccgcccttag tgcttgatta caggacgaaa
    23281 cctgcaatct gtcaagtaaa ctcaacaaac ttcggaataa aaatcccgaa gagtcagaga
    23341 attactcgcc tttagctgct ttgaaagctt cagccattgc gttgttggag aagtttgcat
    23401 cttcctgttt gttaacagtt gcgattgcat ctttctcgtc agcttcgtct ttcgcacgaa
    23461 cagacaggct gattgcgcgg tttttacgat caacgccggt gaatttagct tcaacttcgt
    23521 cgccaacgct cagaaccagg gtagcgtctt caacgcggtc acgggatgct tcagaagcac
    23581 gcaggtaacc ttcaacgccg tcagccagtt ctacggttgc gcctttagcg tcaactgcag
    23641 ttactttacc ggttacgata gcgcctttct tgttcagagc aacccagttg ttgaacggat
    23701 cttctgcgag ctgtttaacg cccagggaga tacgttcacg ttctgcgtca acctgcagaa
    23761 caactgcagc gatttcgtcg ccttttttgt attcacgaac tgcttcttcg cctgcaacgt
    23821 tccaggagat gtcagacagg tgaaccaggc cgtcgatgcc gccgtccagg ccgatgaaga
    23881 taccgaagtc agtgatagac ttgattttac cttcaacacg gtcgcccttg ttgtgggttt
    23941 ccgcgaactg ctgccacggg ttagctttgc actgtttcag acccagggag atacgacgac
    24001 gttcttcgtc gatatccaga accataactt ccactacatc gccaacgtta acaactttgg
    24061 acgggtggat gtttttgttg gtccaatcca tttcggaaac gtgtaccagg ccttcaacgc
    24121 cttcttcgat ttcaacgaag cagccgtagt cggtcaggtt ggtcacgcga ccagtcagtt
    24181 tggtaccttc cggataacgt ttagcgatag ctacccacgg atcttcgccc agctgtttca
    24241 ggcccaggga tacacgggta cgttcgcggt cgaacttcag cactttaaca gtgatttcgt
    24301 cgcccacgtt gacgatttcg ctcggatgct taacgcgttt ccaggccatg tcagtgatgt
    24361 gcagcaggcc gtcaacgccg cccagatcaa cgaatgcacc gtagtcagtg aggttcttaa
    24421 cgataccttt aacttccatg ccttcctgca ggttttccag cagctgatcg cgctctgcgc
    24481 tgttttcgga ttcgataacg gcacgacgag aaacaacaac gttgttgcgc ttctgatcca
    24541 gcttgattac tttgaattca agctctttgc cttccaggtg cagagtgtca cgcaccggac
    24601 gaacatctac cagagaacct ggcaggaacg cacgaatacc gttcagctca acagtgaagc
    24661 cgcccttaac tttgccgttg ataacaccgg taacagtttc agcatcttcg taagcttttt
    24721 ccagcgtgat ccaggcttcg tgacgtttag ctttctcacg ggacagcaga gtttcaccga
    24781 agccgtcttc tactgcgtcc agagcaacgt caacttcgtc acctacctgg atttccagct
    24841 cgccctgggc gtttttgaac tgctcagccg ggatggcgga ctcagatttc agaccagcgt
    24901 caaccagtac tacgtctttg tcgatagcaa caacaacgcc acgaacgata gaacccgggc
    24961 gggtttcgat ttcttttaag gactcttcaa agagttgagc aaaagattca gtcatgttta
    25021 atcttcaggt ttatatttaa cgtccacctg gctccatgcc ggatggggtt gtttaacata
    25081 cccgctgtca ttccattgca acgggggtac tgcaaattcg gtcgcttatg cgagagccaa
    25141 tttctggcgc gcgtattgta gcgctttttc aatcacttgc tcaatgctta aggtggtgga
    25201 atccaacact aaagcatcgg ctgccggaac cagtggcgct accgctcgat tacgatcgcg
    25261 gtcgtcacgt tctttgatct cggccaaaag gcgctcaaag ttaacactaa agcccttctc
    25321 ctgcaactgt agcatgcggc gatgcgcacg ttcttccgag gaggcgtcaa ggaaaatttt
    25381 cactggcgca tcagggaata ccaccgttcc catgtcgcgc ccatcggcaa tcaggcctgg
    25441 taattcgcga aacgcgcgtt ggcgacgcaa taatgcttca cgaacgcgtg ggaatgccgc
    25501 gacttgtgaa gcagcattcg ccacctcctg agtacgaatt tcgccgctga catcttcccc
    25561 ttcgaggatc acttccagat tgccgttggt tgacacaaaa cgtacatcca gatgggatgc
    25621 cagcggcacc agcgcatctt ccgatgcaac atcaacatgg tgatgtaatg ccgctagtgc
    25681 cagtacgcga taaattgcac ccgaatccag cagatgccat tgcaacgctt ccgccatagc
    25741 cttacacaag gtgcctttcc ctgcaccgct tgggccatca atggtaataa ccggggcaat
    25801 tgccgtcatc tttatctcct taaaacaggc gtaccgttaa cataaccgcg cgcattatac
    25861 gcgccgacgc cacaaatcgt taacgttgtg tgcaaaaacc agttttgtct gtattcagat
    25921 ggggatttat tgcgcaatta tagcgggctg gcagaagacc agcccgaaag atgacaatga
    25981 tttacttacc agaggcgata cgatcacgga tgtgttgcgc acgctctgtt gatggtgggt
    26041 gagaatcaaa catggactgg gtgtgaccgc catccaggct agcgagtttt tcaaagctac
    26101 caaccagccc ctgggtactg atgccacgtt tcttcaacag atcaaaggag aaatcatctg
    26161 cttctgactc tttatcacgg gagtatttag cattgatagc gccttctgcg atatcaccca
    26221 attgtgagcg ggaaagctgg gaagccacac cgctggtagc tgaaatggca tcgcgtgcgg
    26281 ccacgatcgc ataagaagct ttcatttcag ccagcgagtg acccaacgcg acgtggccca
    26341 gttcatggcc cagaacgcct tcaatttcgt tgtcgttcat catgtccatc aggccactgt
    26401 agacacgaac acaaccgttc gccatcgccc atgcgttgac gtcgctggtc atataaacct
    26461 tatagttgac tggcgtgcca ttaatattgt tacccaatgc tttggcgatt tttgccagac
    26521 gtttcccgta cttgctggat ttgcttgcca ctttattgcc gctgtccatt tcgacacagc
    26581 cctgattggc gattgcttta gcatcagcat cgcttaatgt tgcggcttta taagcattca
    26641 gacctgagct gatagccaaa tcggtattaa taccgtgcgt attctgacat cctgtcagta
    26701 aggctgcaga ggtcgcaatc gccagcaata atttagtatt cttctgatta gacttgagat
    26761 aaatgacagg gaataagtga gatatttatg ggaagaactg ggtcaaaatg ggaagagact
    26821 aggaggaata tgcaataacc ttacagtatg tgaaaatcag accggcccga aaaaaaaaca
    26881 gaactcgcgc cagcctgatt gcagatatta ctcttttttc tccgtatctg catcgggttc
    26941 atcagcaaat agcttgccct gcatccgatc cagttcttct tttcttaccc gcttaaccac
    27001 gctgtagacc cactgaagcg aaacaccaaa tttgcgggcc agttcgtggt ggttgcgtcc
    27061 gttaaactcc ctgaagattt cccggtcgcg ctgactgacc ttccatacca tgcccatcgg
    27121 gaaataaacg ttttgcccgc cccagacctg catcattcgg ttcgcgacgg cctgaccaat
    27181 ctggtcggca acttcgggct caatatcaat aatctcgcga acggtctcag aggtatgctg
    27241 tgccagttcc accaggagtt ccggcccctt acttcgaaac tgattcaggt cgctcatgtt
    27301 tgactcccgc agctctgcgc tgccacttct tcagtttctc aataacactg cttgcctgtt
    27361 cagtactgag ccagcgcagg gcgctgatgc ccgtttcccg cttgatccac ctcgctaatg
    27421 cattttctga acggtcacga acaatgccgg cagcagccat ttcaagccat agcgcacgaa
    27481 ttttcctgga ctgcggatgg ttatcaagcg gtaaaccgga gctggctttt ctggctggtt
    27541 taacgcgaaa gcctttcttt ttcatggatt ccagcacgca gtttagttgt gtggtatcca
    27601 ttcctttggt tgaggcttta ccggtcagcc cctgtaacat ctggcggtag gtgtcttcat
    27661 ccatacccag ttcattacgg gcaatatgga taagctgtat caggcgtttt ttctgcatat
    27721 catctccttt ttttcagtct gtcggcaaca atgtcggttg cagctggcag ggtgactggc
    27781 cagaacaaca tgacggcggt catgtacagg atgtaatgcg cggtgtcgta gtgcctgcca
    27841 tagcccaggg aacgatgaag tcttgcgctg catgatcctg cgtacatata ccagaaaaga
    27901 aaacagacaa tggtttcagt agtcattctg aatacctccc cattcgatat gaatattacg
    27961 ggcagcaatg acagggtcgt tattccacca tgcacctgac atgtattttt caacctgttc
    28021 gcgtccggca ataacaccaa ttgtgatccc cggcctgacg ttcttaaaaa aggcgcgggc
    28081 aaaaaggtat ctggcagata ttcggcaggc ttttaatttc cggcttttac ctgatagcgt
    28141 aatcatctgg cctccagttt ctgttgttcc tgcccactga ccgggcggtg cagtctgacg
    28201 ttctgccctt cacgaaaccc cgcatagcgc gaggcgtcgc cattgcggct tcttcccggt
    28261 ttacgcgccc tggtggtttg cgtctgcggg tatttatgtt ccagccactg ctgcatcagt
    28321 tcacgctcat catcggtcag ggcaaaggac tgtatttcac tgataacggc cagcacccag
    28381 ccttcggcaa actggtctcc acggctggtg cgggtggcgg tttttattct tttgttctgt
    28441 gcactgatat actgctgacg cgcctttttc agctgacggg ccagcacttc ccaggtgtat
    28501 gcagccagtg ccgcacgttc ccggttgccg tagaacccca cagacggatg cgtgccgggg
    28561 tgaatgatgg agttaacacc aaatacctcg cggatgatgt tcatcaggcc cagcatgtag
    28621 cgcggtggac ggagactgcc tgtcggccag tagtgactga tggtttcatc aatatcactc
    28681 atagcaatgt cggaatgtgt gatgccgtga acatccatca gtttacgggc tcggcgcagt
    28741 gccagagcgg cctcgtgcgg gttgccggat gcggccagcg ccagcaactt tttcagtttc
    28801 tcaatgtgtt tattctggtc tgtcattgtt ctgtatctcc ggtatttttc tgccgtttcc
    28861 atgcccggac agcgtcggac agctctttca ggctgtatgc tgctttaagc ttttcccata
    28921 accactgtgt tgttatgtgc atcagcaggg cagccagggc tgcccccgca ctgaggcatg
    28981 tcgccaggcc agtaagaatc agtgtccatg cggtgatttc cctgagtatg tcagccattg
    29041 aatgcctccc ggttactcgt tcgtgtaaat cacgcccagt cgtgcagcca gacgttccag
    29101 ttttttctgt ttgtggaagt caatcagccg gtccatcccc tgaaggcgca gttgctctgt
    29161 catgatttcc acgtctgcca gctctgccgc gaggtcactt tcgctgccct gtccgttcag
    29221 gttgcgggcg gcactggccg ccagttcagc ggcctcttct gccagtttca gggcctgtgc
    29281 gtccggcccg aaacgctgca gggccagacg gtagagggcg gtgcgggtga gttcggtgtt
    29341 tcgtgtcatg ccgcgccctc agtgcttccg gctgacggtg atgtgcaggc cgccttctgc
    29401 agtggtttcc atccggtacg gcacctcatg ctctgccgtg tgggtgagtg tgttcatcag
    29461 tacctgcagg gcagcctcct ttccgttggt cgccacaatg gcctgtgtgg ccatgctgat
    29521 tagcgccgtc aggacgtgct tcacatcggt gaggtcgcgg cattcacact cgttgacata
    29581 gtgttcaaca agggttcggg tgcgctgtcg tgcttcctgt ggggtaatca ttgcgagtcc
    29641 tccctgtcag ggcgggagaa ttccatgacg ggcacgtctg ccgaaaaatg ctggctgcag
    29701 tacgggcaga ccagggtgac gcgtaccgca gggatgtggt atttaccgga catcacggcg
    29761 atggcgctgt gaaaacgcag ggctgttata tccctctcgc actgaataca tttaaatatc
    29821 atgatttaat tctcctctgt ttccggcgtg cagaagcccg cggcgctgac gtcggaataa
    29881 aaaagaaaat gtttttatta aataattaac gtggtgtgtt tactgcacat cctgctcaaa
    29941 aggaattatt gaaaaatcct caatgtcgct tttaatggaa ataccgggaa tatttttcac
    30001 ggcctctttt tcattcagga tagcgtcttt atttatttcc tcttttacac gaataaagcg
    30061 ctcaagcccc agacgtctca gtaattcaat aacattatcc gccccacgga tactgactga
    30121 tggcggacgg tttcgccact gcacctcgcc ggtggtgagg ttagcgaact tcaccttccc
    30181 gttgccggtc agttcatcac ggtgtgcctc acaccatgtc tgaataccgg actgcagttc
    30241 ggccatgcgt tttttcaggc tctcggtgag cggggcataa cgtgcggtga tatcgccaat
    30301 ggcgtcattc atttctgttt cagccctgac cagttcacgt tgtgcgtcac cgagtagtct
    30361 gattccctca atgacctctt cacgtgtccc cggcacccag agtgctgctg cggccttgat
    30421 acgttttgca ccttttgtac tttttgccat tttttatgat ttctccagtt gtgctgatta
    30481 ccacaaagat tccggccaca cgacgcgaca gccgtgcagt tcgaaaacgc cctgacggaa
    30541 atatcccctg tggtcatgtc cggtatacag ataacaggcc tttccctgct caagcatgcg
    30601 catgcaatgc gcactccggg aaacgcggat gacaggtttg ttacccctga tggtgatgct
    30661 ttgtacatcc gtgttcgtcg ccttaagcgc cataatggct gactgcactt tgctgatttg
    30721 ctggttgata cctgtggtgg atttcattat taaacccctt tgacaacgtc agcgttgacc
    30781 tgtggaaccc cgatttcagc ggccagattc atggcggcta ttaccaggtt actgacggcc
    30841 agcggataca gcaggctgac catattttta cggtgacttc ccggattgct caggcgggca
    30901 cgtatggcat ccactgcacc ggcgtccata atgtccgtca gctgtttacc ggcccgttgc
    30961 agtttgaacg tcagaaattc ttcaaggtta ttgtccagag gcagaagttc gaccacctca
    31021 cagcgctgaa cgacttcacg gacttccata ttgcgttcag acagttttgt cgccagttcc
    31081 ggctggccaa tcagcacgat ggacagcagt tttttgaaac cggactccag ctcaaaaaag
    31141 cgtttgaggt gtttcagtgt cggaatgggc agactgtggg cctcctcaat caccagaacg
    31201 tggctgaacc ccgcctggct gctgtctttc aggacgcgat gcaactggcg aaaacgggcg
    31261 tcctgactgc gtctgatgct ttccagtggt gcgatggtac tgataatggc ttcggcaata
    31321 gctgctgcct tcagggtttt ccctttcaca tcgttgtctt ccatagcgat gatgtatggc
    31381 tcgataacaa ttaccggcgc attctcgcgg ttgatacgtt cagtcaggtc gcggcgcagc
    31441 gtggatttac ccgcaccgga ctcaccgatg acggccataa acccaccatg acgggctgtc
    31501 tggtacagcg cctcacgcac gtagcgaatg tccggggtgg tgaacacatc atcagaaccc
    31561 tgcatggctt cgtcggcgaa cgggtcacgg aaaagaccaa acgctttttt ggttgctgga
    31621 aataacacct gttttttgag taacatattc tcttcctcac tgaggctcgt tttatctgtg
    31681 gtacccgctg tacggggcgt ggccgcgccc tgtacagcat caaaactctt cgttgtatca
    31741 atcccctgac tttccagcca ggacgcaaga cgccggcgca cttctccggg gctggtgcgg
    31801 ggccacgcgt tatgattcac aatctgggcc agcgtggcct cagaaacatc gacagctctc
    31861 gccaccaccg cctgtggaat acgggcctct ttcagttgct gcttcagtac cagcatgttt
    31921 ccctcctcag ttgccgttaa caatgctgat aacactgctg cgggccggtg tggtcagcgt
    31981 ggccatgact tcatccagtg cggcttccgg tacgccgtcc gggtactgtg ccgttaactg
    32041 gcggtaatgt tccggcgtcc aggtaaggcc gtcggcgctg aacttatcgc gcagggcttt
    32101 cgcggcctcc acatgagtca tgggacgttg ttcagtgcgc ggcccgcgta cgtcagaggc
    32161 ctgaccacgc ttcggcatat aggccggaag tgtggtgtcg tcgatatgtt tatacgggtc
    32221 aagccgcccg ccgaacggca gcgccttcgc cttgcgtgcg gcggctgcat ctgcggcgtt
    32281 gtctgtaccg gtaaccagcg cttcggtttc ttttgccgcc atctgtgccg gggtttccgg
    32341 cagggctttg taactttcgc caaataccgc cgcgccttca gcaaagccaa actcgttctt
    32401 tctgacctct tcgaccagga agaacgtctc gtggccgtcc tcaccggtca gaaccacctg
    32461 tgccacatcg ctgcgccatg ggttacgggt aatcatcagt ttttcaccaa ccagtacgcc
    32521 cggtaccgtt gatacgtcaa attcagtgcc ccggaacgag acacgaagtt ttggcgtgac
    32581 tttgcggagt tctggtgccg ccacagccag ttcacgacat acctcaacgg aaggcgcttt
    32641 tttcagctgc tcagcagtaa tcttcagcca gatatccgtg cgggttttac cgtggcggct
    32701 gtgaacagcc gtggcgttaa agtggctgcg ccatttcgcg gccagcgcgt tgagttcttc
    32761 cagactgtga accggccgga acttcagacc cggctccagc ttgcgttcga taatgtcacg
    32821 cgccttttcc acctgtccgg tggcgcgggc gttatgcggc ttgtgcgcta tcaggtcgat
    32881 gcccagtgag cggcacatgt ttttcgtcat acccgcggtg tttgccgagc cggggtcgag
    32941 atagagtatt ttcggcacgc cgtgcagcac gtctgcgccg ccacgctcct gcatggcgtt
    33001 gataagcaca gaacacaggt tctcacctga ttccgcgccc gtcacatact caacgtaaat
    33061 ccagccgctg gcatggtcgg taatctcgta actccacacg cggtcactgg cgatacgggc
    33121 aaggttagcg ggcttgttct tgtagaactt cgcgctgtcc atcacctgca gccctttatg
    33181 tccattgctc aggtagtaaa gcgtgcagag tgaggcgtca atctgccaga catgattggg
    33241 atgcagactg gccacttcgg tatgtggtgc aggggcatcc agttgttccg ggtgcaggcc
    33301 atagttacgc agagcacggc tgatggcatc ttcagacaac gggaaaaact cactggtggt
    33361 ttcatctgtt ctgcctgcgg tgataaagcc gttagcccgc agggtttcca ctgcatctgc
    33421 gatggaatag agacgcttac cgttcttgcg ggtggcctca cgcagtgtgg cagatatcag
    33481 cgcggcttcg tcgcgggtca gggcgctgcg cccggcatcg gcgcgttttt tgcgtttatc
    33541 agtcacagat acctccttca gcctgcgcag cagagtggcg cgggacatgc caagttcagc
    33601 acaggcagcg tcgtatattg caccgcgttt accatgcccc gcgtcacgtg ccgcgcgggc
    33661 tgtttcaacc agtttttcag tcagtgccgg ggtcatagct tgtcttccct gttatccgat
    33721 tctggcggca atttttctgg cgaggtcgca cagtgtttcg ccatcgcagg ttttcaccac
    33781 ggtatttacc ggttgcggtg caactaccgg gcgtaatgct gactgattct gcagacgtct
    33841 tatctgctgc atcagcatca cctccatcgt cagtacaaac gggtgcgtct cctgtgcggg
    33901 tacgcagatt tcaccggaag gggtcaccac gcggaaaccc tgcaccatct ccggcagcag
    33961 attacacagt gcgtgcccca gtgcctccgg gctgtccatc agggtatttt gtgtgttatt
    34021 cgtattcatt actgcatatc ctccggtcgg ttgatttcag gttccggttc ggtcagccag
    34081 gcgggggcat cgttacccga tggagcggcc tcaaggtcaa acgtctcacg taatgcatga
    34141 acactgcgtt caatctggca gaccagaccg gccatgaaat ctctgggggt atcgatcatg
    34201 tttttggtgc agtattcaca cagggtctca aaaacactgg acagccggac ggcgatagcc
    34261 gattcggcct caaccgctaa tgccgtcact tccgcccgca attttttcag ttcttcgtct
    34321 ggcggcggag gttgcaggcg cgatttcttc tccagttttg tggccagttc gttgattttt
    34381 tcgtcctttc cggcaagcac ctgttgctga gctgcgttgg tttcgcgcgc ttcacgcagg
    34441 gcggccttca gttcgcggct ggtcatgcga tcaatatcat caagcgttgc accggcgacg
    34501 gttccaccat cagctaatgc gtcgagttct tcgtcatcca gaaccatcag ttcatataac
    34561 ttggtttttc ccaaaacgct cagcgctgag cgttttggct gttcatctcc attgccgaga
    34621 aatttcacgc tggcctgcat catgcgacga gctacctgtg gtgctaatcc gaggtcgttt
    34681 tccagaatat ttgtgaaatc accatgcggt tcattttctt ttaagatgat cagccgctta
    34741 cccgcttcca acatagattc agcactctgc gccatataaa aacgtgcttc gtgaacgatg
    34801 cgttcacgtt cataaggcag tccatcacca aactgctgca tgatctccat gcgatgctgt
    34861 gtcatggcat tcaggctgac gttgagatca tccgacagcg gtacatcggc gttcagttca
    34921 gtgttaatcg gtgatttggt acgtcccatt gattactcct tacaaacgac tacctgaaat
    34981 gacacgttgg ttaatttcgt taatacgatc ctgtgcacgt gccatctcgt tactgtgggc
    35041 catggcgatc tgcagtaact ggatgcccgg tgcaaaacgt ccgttctcca gtttcagagc
    35101 cagcccttct tcaatgaggg tgttgagtgc ccggttgatg tttgccggtg actcgtgcag
    35161 tgctgtcgcc agttcaccgt tagaaatacc gttcagggca tgaccgcgca gcgctttgag
    35221 tacccggagg atgcgactgc cggagcttga aacattcgtc ttactcatct gcatacctct
    35281 tttgcgatat gtgataacct tttacaaaga ctcaaaatat ttaggccgcc tgagctgttg
    35341 atttcagtcc caacttcacg gcgatttcat gggatttacc gtaacgggct ttggtctgcc
    35401 cgttgagaac gcggtatacc tcattgcggt tgtagccgtt ttcttctgcc cagcgggtga
    35461 aagtgatccc gcgctggcgg aagagagctt tgacttgttc tgcagtcatc gttgtctcct
    35521 ttgttgatgc aatgatgttt gccttatatg tgttagatta ttgctcataa ttatgagcat
    35581 atcaagatag agattcactt ttatgagcaa agatatagga gagcgcgtta tttctgtgag
    35641 gaagaaagca gggttgaacc agagagaatt tgcagctcgt ttaggtattt ctaatggtgg
    35701 tatcagtcag attgaaaatg gaaaggcgat gcctggaggg gagtttctgt taaagatgca
    35761 tcaagagttt aatgttgatg taaattggtt gctcactgga atgagcacag atggtatgac
    35821 tagaaaccag aatcaaattt ccccagaaaa acaaaaacta atagatactt ttgacgacat
    35881 gacaccagac caacaacgct catttcttga gattgggcga ttctatactc agccaaaacc
    35941 aggaaaaatc gcaggctgat actgacccgg acacaaagga caggtggttg atctggatgc
    36001 tttcagaaaa catcgccagt gacatagtgg aagttgtttg gtttaccgga aagcattgtg
    36061 ctttccggtt ttgtttcaga agttgcagat tagcagttca cggcgcggcg tgggtttacc
    36121 cgccagactg tagttgatat tcactgtctg tatgttcagt ccagtgaaca cctcgcgcat
    36181 ctgcgggatg tcgttcaccg aaattatcat ttttcctctg atgcaccggg ccagctctgc
    36241 cagccgcgag tagttccctt caggaaaatc cacaccatag ccttccgtac ccaggtacgg
    36301 tgggtcgcag tagaacagcg tgtgcggacg atcataacgc tcaatgcact gttgccagtc
    36361 catgtgttct atgactgttc tggaaagccg caggtgtgcc gctgacagtt cttcttcaat
    36421 acgtagcagg ttgaagcgtg gcggggatgt ggtggaggta ccgaagctgt gctctgccac
    36481 cttgccgcca aacgcctgct tctgaaggta gtagaaccgt gccgcacgct ggatatccgt
    36541 cagtgtttct tccggggtga tctgcagcca tttgtagatc tgacggctga ccagcgccca
    36601 tttgaactgg cggacaaatt cttccaggtg atgctttacc acccggtaca gattcaccag
    36661 ttcaccgttg atatcattga tgacttcgat cttgccgggt gtcttaagaa aatagagcgc
    36721 tgctgcccca caaaacggct ccacataaca ttcatgcgcc ggaaacagcg gcagaatgtg
    36781 ttttgcaagg cggcgtttgc caccaatcca cggcacgatg ggtaatgtct gcattttcat
    36841 aatctgcaag ccttttacaa ttattaaaaa atatggcagt ctggtcaggt ctcgcgagac
    36901 tgactgaacc ttggtcggct cacagcgcat tcctgtgggg cgatgaccag cccggctttc
    36961 gggtgccggg ctggtcgttc tttcatgatg cggcagggat ggcgggattt ctgttaatgt
    37021 ggtttaggga ttatccgggg cgattttctg accttatccg gtccagggca taagtaatac
    37081 cttctgcaaa aacagaagta tcaaactgct tttgtattcc ctgaaaatga aaagcggcac
    37141 gacagacact cagttctccg cggtataacc ggataatatc ttccagaaca ttgttcactg
    37201 cttcagcacg gcgctgatgt tctgttaacg ttaatcgggg attcatgatg cactccttaa
    37261 atgatgattt ttatgtactc accggcaaaa tattctgccg attactgaac acgcatccgg
    37321 cacctcaggt tttgatttat tctggttttt tcgatatccc ggaccaggtt gatcacgacc
    37381 agaaaaagtg ccggtgtttt attgatacgc tgatatggct tcgggataac agctatattc
    37441 gttactctca gttgctggct gtgggagcgg ctgatgtcgt cctcacggaa aaaacgctct
    37501 gtctgctcaa tgccatgccg acctttctgc agccccggcc cgtaccattt aaagagtcac
    37561 ttctggatgc agtaaaaacc ggtgaaaatg cagtcatcgc tgaatgcgta tcccggatta
    37621 tgcgttacgt gtttaatgaa cgtaagtgag gtttatccgc tgtctgcata atcccgatag
    37681 ccagtgcgag gggaagtaat tccggggaaa ctctttcaaa cagcgatgcc cattctcctc
    37741 tcgccatcac tctgtccagc ccgccctcca gttgcatttc agcaatcttc ctgatttccc
    37801 ggaacaacgc cgctttgatc tcttcatgct cagctttatt ttccggtgtc agaaggtatt
    37861 cgtcgaagaa ccggggaggc tggttaatcg ggatgtgttc ctgtttgccg tacttcgggg
    37921 acgaacaaca ttctgttgac tgaccagtga gtttacgtaa ctccttcatg agcagctcct
    37981 gatcgtaaac tgtcatcagt gccgcaatgg tggcatgcag tgcatcgggc agtatccagg
    38041 gttgccggcc cgtggggcat ataacatcca gcagctcatt cgtccgacag atacgctcct
    38101 cgccgtatga caacaggccc tgtcccgtgt attcctccag cctgatcact gtgccagccc
    38161 gtggtttctg ccatgtgctc agatcatccc cactcatacg gcgctcaccg tccacgtctg
    38221 cggcgtcgac aatgacgctg tttccgaatt cctgtttcac cacttcctct attcgcgcca
    38281 gtacgtaact tttaccgctg cccacaggac cggacacggt gacagtgatg accggattca
    38341 gtgtctgcgt catatcgtat tctcctctgt gaataattca tcgtttatcc tgcacatccc
    38401 gtatccccgg ctctcttaac gcgctttaaa atccttcgcg ccctgtattt gtgatgctgt
    38461 ctccaccaga taaggagaca cacatgaaaa acctgaaaaa attcattccc cctgttaaaa
    38521 aacctcgcct cagcggctgg ctgctgacct cagtgctgtt gctgggcacc atcgctctgg
    38581 tctcaccaca gcagctgcct gttgtgatct acaagctggc actcatcacg ctggcagcag
    38641 tgctgggtta ctggcttgac cgttcgctct tccccaaagc ccgtcccggt cagtacctga
    38701 aacatgacga caggctgatg gctgaagggc gtttcccggt acagaccggc cttcacctgg
    38761 tgttttctgc tgcgttaatc cgccgtgcac tgattgttgc agcggtctgc ctggctgttg
    38821 cgatggggct ttaatcatga actggccgca gatcacctgg attgtatgca tgtccctgaa
    38881 actggctttc gaagcctttc gggtcttcat cagaaccgaa cgcctgtcag tccgcgccgg
    38941 gacctttctg gttcatatgg catgggtatt ctttgtcgca atgttgctct ggtgtggcgg
    39001 ctttttcagc caggcatgcg cagcacaacc tccgcaggct gcgctgcagt atcgcgatga
    39061 tgtgatccgt aatgcccggc ttgaatgggg actgtctgcg ccggtggccg atttcgccgc
    39121 gcaactgcat caggaaagcg gctggcgacc tgatgcgatc tcgccggctg gcgctcaggg
    39181 actggcgcag ttcatgcctg ccactgccga ctggataagc cagttgatac cgatgctgag
    39241 cagtcgtgag ccgtttaatc cggcatgggc tatccgggcg ctggtcagct atgaccgctg
    39301 gctgtggcag cgtgtcagcg ccgccagtga ctgcgagcgt atggccatga cactgtcggg
    39361 ctataacggt ggtctgggct gggtacaacg ggacaggcgg cttgcatcac agaaaggtct
    39421 ggacagcacc cgctggttcg gacatgtcgc cacggtgaat gccggacgca atgcggccag
    39481 ctggcgggag aaccgccatt atccgcagcg catcctgcgc gaactggcac cgcgatatct
    39541 cacatgggga ggcagcagtt gtgtggcatc tggttaaaaa gctgccgtgg cgcggcattc
    39601 tgctggccat tcttatcaat gcctttctgg tcggcctgta tgccatggga tacagaagtg
    39661 gtcatgactc tgcaaagcgt gacggtgata ccgcgctaag tcagttgcag tcagcatttg
    39721 acgcgtacaa aacggagcag gcaacgcttg agaatgctgc gctgcgggcc tgggccagac
    39781 ggtatcagga gcaggtggcc gccgggcagc gggctgaagc cggttatctt gagcagattg
    39841 ctcaactgga gagccggaac aaacaactac aggggcaaat taacgatgtc acacagcgct
    39901 ggattgatga aaaaggtaag agtcatccca ttgagtgcgt gtttactcgc ggtttcgtgc
    39961 gccagtacaa cgccgcactc ggatatgaca acgcatccgt cgacaccggt cattcagact
    40021 cagttgccgc cactggcacc cgctctggca cagcgaccgg gcaacctgaa accactgaca
    40081 cccggttacg cgattcgggt gtctcccagc gtgacgttct cgccaacatc atcgacaacg
    40141 catggcaatg tcgtcgctgg cggaaccaga taaacgcgct gctggatgaa cgggaaggat
    40201 tacagaaatg acactgcagg ttgaattctg gacggtggtg agttttctgc tcaccttcat
    40261 gaggtttgtg ggagggctcg ccaaatggtt gttcagtaaa acagaagaac gccaggcggc
    40321 acgattcgcc tcccttgaac aggccctgca acaatccgcc tccaactggg gcgagctgga
    40381 aaaagaattt atgcgattta aagcggattt accgctgaat tatgtccgtc gagaggatta
    40441 tatccgtggc cagacagtca ttgaggccaa actggacgcg ctttataaca aactggaagt
    40501 ggtacagcag taccgcaata ccggaggtca ataatggtcg atattacccg ggtacgccgc
    40561 gaatccctgc gctggagtct gctggttgcc ctgaacaaga cccgccctta caccgccagc
    40621 gagacgctgc tgctggatgt gtcccgtgcc atctacccgg acaccacacc gctggaactg
    40681 cgccgcgaac tggattatct ggctgaccgt aaaatggttg agctggagaa aaaaccttct
    40741 ggcgactggt ttgctgacct gacccgcctc ggcgtagacc tggtggaata caccgtggaa
    40801 tgtggtccgg gtattgcccg cccggaaaag tactggagtg aataatggcc agacgcagca
    40861 caatagaaaa gctgccggaa gacgtgcgcc gctggcttga acgggcgctg actgaatccg
    40921 gcttcagcgg gtataacgag ctggagtcac tgttgcgtga gcgggggtac gtcatcagca
    40981 aatccgctat ccatcgctat ggacagaaga ttgagcgccg ctatggtgct atccgtgcgg
    41041 caacagaagc ggcccgcatg ctgaccgaag gcgcagcaga cgatcaggat gcgcgttcgg
    41101 aggctgtgat agcccttatt cagaccgagc tgttcgagag tattgtccag ttgcaggagg
    41161 cggaagaagg cgaagtcgat cctaaagaac gcgtggccct gctgtcgaag gtggcgaaga
    41221 atgtggctac gctgtcccgc gcgtccgtca acctcaaaaa gttccagtct gaagtacggg
    41281 ccagagcgca gcaggcagcc agcaacgccg agaaaattgc ccgtaagggg ggactgtcaa
    41341 gcgacgcagt acaggcgctt cgtcgcgaga ttctggggat tgccacatga caaaatcatc
    41401 cggagtgatt ttaaacgccg ctggcggcgg ccccgaaggg atgagtccca tggacgggag
    41461 gaataacctt gctcccgttt tgcctgatac ctcggcgctg gatgcccctc ccgttctgtt
    41521 gccttaccag cagcgctggg tggcagacac ctctccgctt aaggtgatag aaaagagccg
    41581 tcgtaccggt attacatggg ctgaggcatc cgataacgta ctgaccgccg cctcttctgc
    41641 gccagcaggc gggatgaatg tgtattacat cgcttataac caggacatga ccgtcgaata
    41701 cattcaggcg tgtgcgatgt gggcacgggc attcaactat gcggccagtg aaattgaaga
    41761 aggattctgg gaagaggacg acgacgacaa acacatcaag acttacacca tcaaatttcc
    41821 tgactccggc tttcgtattg ttgcgctctc cagccgcccg tctaacctgc gtggccgtca
    41881 gggtattatt gttatcgacg aagcggcgtt ccatgagcaa ctggacgaac tgctgaaagc
    41941 ggcgctggcg atgcttatct gggggggaaa ggtacgcgtt atctccaccc atgacggtga
    42001 cgacaatccg ttcaatacgc ttatcgggga tatccgtgcc ggacgtcagg gaggcagcat
    42061 acatcgcatc actttccggg aagccgtatc tgaggggctg ttccggcgcg tctgtctgcg
    42121 caccgggaag gaatggtcgg aggcatccga gcaggcctgg atggcatcgg tgtacaaatt
    42181 ctacggtgcc ggcgcatccg aagagcttga ctgtattccg gccaacggtg gcggtgcctg
    42241 gctgtcccgt gccctgatag agtcccgcat gtccgctgat acgccggtat tgcgtctgac
    42301 ctgcaaggaa ggttatgaac tgctgtctga tgaggttcgc ttccgcgaga cgcaggactg
    42361 gcttgatgag tatctgaaac cattgctgga ggcactcccc actgatgccc gctctttcct
    42421 ggggcgcgac tttggccgta gcggtgattt gtcggtggac tatcccctgc tgcaggagaa
    42481 gaacctggta cgacgcgtgc cattcgtact ggagctgcgt aacgtgccgt tcagacagca
    42541 ggagcaaatc acctggtatc tgatggatgg cctgcccggt ctgctgggtg cagcgtttga
    42601 tgcccgtggt aatggtgcct atctggctga atacgccatg cagcgctacg gctccggccg
    42661 ggttcagcag gtgatgccaa ccgaaggctg gtaccgggag catatgcctc cggtcaaagc
    42721 tgcactggaa gacggcaacc tggtggactt accaaaggat gaagacacac tggatgacct
    42781 gcgggccgtt caggtggtga acggtgtccc ccgcgtaccg gagcaacgct caaaagcaaa
    42841 ggctgacggt ggtaaacgcc acggggattc agccatcgca ctggcgctgg cgtatttcgc
    42901 cagccgtgaa attaacaaag ggccggtgaa ggcaagctca cgccgtcgtc gtcaggcggc
    42961 ccgtatgctg gagggattct gatggcgagg ggtatctggg tttcacccga tgaatttgtt
    43021 gctttttctg agcctcagaa atcactgacc gcgcagattg cctcccgcag ccgcgcgatc
    43081 gacttttacg gactgggcat gtatctgccc aatcctgatc ccattctcaa ggctcaggga
    43141 cgggatatcc gtatctaccg cgaactgcgc accgacccgc tggtcggggg ctgtatccgc
    43201 agacgtaaag cagcgctcaa atcgctggag cgtggactgg agcgtggtca cgcctctgcc
    43261 cgggtcttcc gtttcatccg cgacatgctc gacgatctgg atctgtcccg catcatcggt
    43321 gaaatgagcg atgccgtgct ctacgggtat cagccctgtg aaatcatgtg gggccgttcg
    43381 gtcaggtcgt gggcggtgac ggatattgtc ggcaaaccgc ctgagtggtt tcagtttgat
    43441 acggacaact gcctgcgctt tcgggcgcgt gatgcgggtg tggagggtga gctgctgtca
    43501 ccgtcaaaat tcgtggtgcc ggcacaggat gcctcgtatg acaatcctta cggtttcccg
    43561 gacctgtcca tgtgcttctg gccggtcgcc ttcaagaaag gcgggatgaa attctggctc
    43621 cgctttgccg aaaagtttgg ctccccgtgg gtgatcggta agcacccgag gggcgcaaat
    43681 gatgcagaga ttgaaaaact gctggactcc atggagcaga tggtggagga cgcggtggcc
    43741 gccatccccg atgacagcag tattgagctc agggcagcgg atggcaaggc agacagcagc
    43801 gaggtatttc gcgagctgat cacactgtca cgcagtgaga tctccattgc attactcggt
    43861 cagaatcaga ccacggaagc gaacagtaac aaggcctctg cacaggccgg gctggaggta
    43921 acggctgata tccgcgatgc ggatgcggac atcattcagg cggcagtgaa tcaggtcatc
    43981 agaacggtgg tcaccctgaa cttcggcgat gtgccgtgtc cggtctgggc catgtgggaa
    44041 caggaggcca ttgatgacac ccgtgccacc cgcgacgaaa aactcacccg ggcgggtctg
    44101 cgtctgaccc cgcagtactt caagcgtgag taccaactgc aggacggcga tattgacgag
    44161 acaccaccgt cggaacgcca gaataacatg ctgccgctgt catttgccga ggcgattgat
    44221 gctgatattc aggctcagca gcagcttgac gacgcgctgg acattctgat gaacggaggc
    44281 gcgttaaatg gcacgctgga acccgtcctg gcacctctgt tcaggcgggt cgaaaacggg
    44341 gttaacccgt ctgagctgct gggcgaactg gcggagctct accctcagat gaacacggac
    44401 gatctgcagg agcggctggc ccgcattctc tttgtggcaa atatccgggg acgtctgcat
    44461 gagcgtgaca acggctgaac tggcgtactg catgacgctt cccccgaagc gggcaatcaa
    44521 ctacctgaag tccaaaggat atcagattac ctgggactgg gaagaaatgt ggcaggaggc
    44581 ccatgcccgc gcctttaccg ttgctaaagt gacccgcctg gatatcctgg aagatattcg
    44641 cggggcactg cagcaggctg tcgatgaagg aaaaaccgat cgctggttcc ggcaggagct
    44701 ggagccggtg ctgaagcgta agggatggtg gggaccacgt gacacgactg acccggtaac
    44761 gggtgagccg gtcaccattc agcagggcag tccgtggcgg ctcgatacca tctttcgcac
    44821 caatatgtcc gtactctaca gcgccggtcg ttgggcggaa cagatggaaa acgtcgacga
    44881 caggccgtac tggatgtata ccggcatcaa cgacagccat acccgcagga gccatctggc
    44941 gctgcatggt ctggtgctgc gctgggatga cccgttctgg caggcatttt acccgccgaa
    45001 cggctggcgc tgccgctgta gtgttattgc cctgagtgcg gcggatgtac gtgcccgtgg
    45061 cctgaaggtt atcagctccg gctctgccat gggccaggaa ctgaaactgg tctcagagaa
    45121 aaccggcgaa atgcggaacg tggccacctt taataccggc accacgaagg tgaccaccga
    45181 cgtcggctgg tcttatgctc cgggggcagc ataccgtccc gacctggccc gctatcaggg
    45241 tacgcttcag ccactggcac aacaggaact gagaggataa caatggcttc cgataacctg
    45301 gtcagtatca ccattaacga taagtccctg cgccggagcc tccgtgcgct ggatcttgct
    45361 gccacagacc tggagcccgc gatgcgcaaa atcgccggaa ccctgctggc ggaaacacag
    45421 tttaactttc ttgatgaggg gcgtccgggg tggatgccct cgctggcagc ggaagaacgt
    45481 gacgggcaga cactgcagga taccgggcgt ctgatggggt cagtatcaac cgaccatgac
    45541 gaccggcagg ctgttgtggg gaccaacgtt gtttacggtg ccattcacca gttcgggggt
    45601 aaaacggggc gtaatgagtc tgttgaactt ccggcccgcc cgttcctgcc ggtgacgggg
    45661 gatggagaac tacagcctga agtggtaatc cccatcctcg ataccattgt ccgccatctt
    45721 gaatcagcgg cccgtcgctg agttttctct cttcaggcgg gtgatttatc attgccagcg
    45781 aatgaggggc tgtattacct ttataaaggc tttacagcct ctgttttata accgcctccg
    45841 gttcaccgca ttgctttccc tgtccttctc ccctgatgtt ttctaaagca gattaaaatc
    45901 gccgggcctg catttctcac aaactgtctc cgacaacata acgcgggaca gcaaaatgtc
    45961 agccattcac atttttaaag ccggtactca taccgatatg cacggcaaaa aactgccgtt
    46021 cacgccagac gatcttgccg cctgcgtgaa agcctatgac ccgtccgtcc atgaagcacc
    46081 actcgtgatt ggtcatccca gaacggaaga cccggcgtgg ggctgggtga aagccctgtc
    46141 gctcagcggc gtcgatctga tggcagagcc tgcccagctg gacccgcagt ttgctgagat
    46201 ggtcaccgac ggacgattca aaaaagtgtc cgcctctttc tacctcccgg attcaccgtc
    46261 caatccgaag cccggcgtgc tctaccttcg ccatgtgggc tttctcgggg cacagccacc
    46321 ttccgtcaag gggctgaaac aggtgtcctt cagtgagcag gaagaaggtg tggtggagtt
    46381 cgccgactgg caggccatca cgaatgcctc cctgtgggga aagctgcgcg attttctgat
    46441 cgcccgcttc agtctggacg aggcagaaaa agtcctgccg gaatggcagc tcaacagtct
    46501 gcgcgaagag gcgtaccgcg acacactgtc gcaggatgca gcaggtgcac aattcagtga
    46561 gacaggcccg gggccgtctt ccgcaagtaa cgaggaatca tcgatgacaa aagaagagat
    46621 tgaagccctt caggaggaga accgccgcct gaagcagcag gctgctgatc gcgatgcgcg
    46681 tgatgcacag gtcagacagg agcaactgca taaggacaat gtggcctttg cagaaaaact
    46741 ggtcgcagag ggccgtctgg ctccccgcgc ctcctccgtg gtggttgccc tgctggatgc
    46801 cgtcgccggt ggcgacaagc cggtggagtt tgctgagggg gaaagccgca caccgctggc
    46861 caccgccttt cgttcattgc tctccgacgg ggagccggtg atgaatttcg ccgaacaggc
    46921 cacaaaagag cgtgtcggcg acacggtgaa ggtggatgtg gcagagtttg cggaagccga
    46981 tcctgagcgt ctggccctgc atcagaaagc agtggccctg tccaaaaaag aaggcatcag
    47041 ctatgaggct gctgtcgcac gctgcctgta atttaaggag agagcatgtc tgattactta
    47101 aaaggtaaac gtgtcgttga tccggtactg accagtatcg cccgtggcta taaaaatgcc
    47161 gcattcatcg gcgaacgtat tttccccgtc gtgctgacgg acaaggaagg cgtgcgtgta
    47221 ccgaccttcg ggaaaaccgc ctttgtggaa tatgacaccg agcgtgccgt cggggcggac
    47281 agcaatgttc tggtccgtga aaaaacaggc acgctggacc tggtgctggg tgaacacgat
    47341 ctggctgcgc cggtggacta tcgcgagcag gcggagtcca tgtttaacga agagagcaag
    47401 gccatccgtc gcgccacgaa tggcgtgaac ctgcgccgtg aacttatcgc tgcccgtctg
    47461 gctcaggatg aaaaggtcta ccgtaccggg cacgtcaaaa aactgacagc cagtgatcgc
    47521 tgggccggtg gtaaggggga ccccatcggg gtgattgaag ccggtatgga agcggtccgt
    47581 acggccacgg ggctgcgtcc taacctgatg accatggggg ccggcgtgat ggcgctgctg
    47641 aagttccacc cggcgattca ggccgccatc ggagccaacg aacgcaagcg catcaccaca
    47701 gaaatcctgc aggacctctt tcagatcgaa gagatcgtca tcggtgcccc agtctccctg
    47761 ccgtccatga aagcggcaat ggataagaac agcgtgccgg cggatatctg gggagacaat
    47821 ctgatgctgc actatgtcgg caaaccgcag ccgggggcgg acagcgcgga cgagaacgag
    47881 ccgtccttcg gctacaccct gcgtcgtaag gggatgcctg ttgccgacaa atacgacgga
    47941 gccggtggca aggtgaagta ctgccgttat accgatatct acaaagtcgc cgtggttggt
    48001 ggcgatgccg ggtatctcat taccggtatc agtaaataag gaggcgttat gggaaccact
    48061 cagcaggtca ttctgatcac aaccgtaacg gcaggggcag cactggcaca gcagcgtttt
    48121 gtcggggcag ataatacccc ctgtaaagcc ggtgccgcag cgctcggggt tgccgaagtg
    48181 gatgctgtta ccggcgacag cacgccggtg agcgttctgg gcattattgc tgtcgaggcc
    48241 ggggccgctg tcagccgtgg tgtggctgtt cagtcagatg ctcaggccag agccgtgccg
    48301 cagtccggcg acggtaaatc ctgtggtatt gcacttgatg aagccggggg tgaaggcgac
    48361 gtcattcgta tcctgcgcgg ggtgtgacat gtactgcacc ctggaggatt tgcttgcgca
    48421 ggtgccggag cggacgctta tcgagctcac cagtgaagag atggacttcg actcacctgc
    48481 aacagtgaat acccgtgtgg tggacagctg tatccgctat gccgacgagc tgattgatgc
    48541 ccatctgcgc ggacgctata tcctgccact ggcagagata ccgactgttc tgcgggacat
    48601 tgccatcacg ctggtccgtt accggctcta cgcccgccgc ccggaaggtg acctcccgga
    48661 tacggtgaag gatgaccaca aagaagcgct gcggcaactc agggagttac gtgataacag
    48721 gctcacgctg gggctgccgt ccactcagaa agatgtgcct gagcctggcg agtttcgtgt
    48781 acgcagtcgc ccggccactt tcggcggtcg tgacggttta ctggagaaat actgatgaac
    48841 gttctgcccg tccttgatgc ggtactggcc cggttacgcg agaagctgcc gcaactgcag
    48901 gtggagtact tcccggagaa accggctgaa tatcgcctga accatccggt tggcgcgttg
    48961 ctgttgagct atgccggttc gcgctttgac aggccggatg ataccggtgc ggtgatccag
    49021 tctcagacta tccagctctg cgtcacggtg gtcttccgcc agctcaacgg taaaaaaggg
    49081 gcgattaatg tcctggatgc tgtccgccgc attctcggtg gccacacccc gcccggctgc
    49141 cgccgccgta tctggctgac ccgcgaggtg tttatcggtg aagtcagggg gctgtggcag
    49201 tacgccctcg acttcgcgac tgaaagcgtc tttatcgaag acagcgattt accgtccggc
    49261 ccgctgttaa ccgaagtgaa ctatgaggaa agcgagtgat gaaagaatac cgctattccg
    49321 gcccggccag cggcgtcacg ctgtcggacg gaaccgaaat cctgctctgg ccggggaaga
    49381 cggtttccct gccggaggag catgactacg tgaaggtact ggtggcgctg aaacatctga
    49441 cgccggtacc tgaagagact aaacccgccg gcacaccggc tgtgcagtca ccaaagcgca
    49501 gaagcagcag tgacagcgaa gtgaaaacgg aggacaccca tggcagctaa ctatctgcat
    49561 ggtcccgaaa ccattgaggt ggaaaacggt gcccgcccgg ttaaaacggt gaaatctgcc
    49621 gttattggcc tgattggtac cgccccgatg ggggatgtca atacgctggt acagtgcctg
    49681 tctgagaaag acgcagcggc atttggcagc cagttcaccg gctttaccat tccgcaggcg
    49741 ctggatgcga tttatgacca tggtgcaggc accgttctgg tcattaacgt cctcgacccg
    49801 gcgaaacata aaacggcgat cgaggatgag gtggttacct ttgacaaatc gacagggcag
    49861 gccagactgg cgcatccggt tgtcgctaat gtggtggtga aaaacagtga aggcagcacc
    49921 acccacacgg cgaacacgga ctaccgtgtt gatgcgcagg cgggtgtgct cacgaacctg
    49981 ggcaaggcta ttgaggccgg tggcagcgtg aaggtgagct atgagtacgc ggacccgtcg
    50041 aaggtgactg cggcggacat catcggcggg gtgaacagcg ccggaaaccg aaccggcatg
    50101 aagctgctta acgacagctt caacctgtac ggctatttcg ccaaaattct gattgcgccg
    50161 gtgttctgca cccagaagag tgtcgcagtt gagcttatcg ccatggcaga gaagctgggc
    50221 gcggtaacct acattgatgc gcctgtcggt accacctttg cacaggctct ggcaggtcgt
    50281 ggcccggaag gcaccatcaa cttcaatacc agctccgacc gcgtccgtct gtgctatccg
    50341 catgtgaagg tatatgaccc ggtgacaaac acagagcgtc tggagccgct cagccagcgt
    50401 gcagcaggtc tgcgtgccag agtcgatctg gacaagggct actggtggtc atcctccaat
    50461 caggagattc tggggatcac cggcgtggag cgccagctgt ccgcgatgat tgatgacccg
    50521 cagagtgagg tgaacctgct taacgaacag gggatcacca cggtattcag cagttacggc
    50581 agcggccttc gtctgtgggg taaccggacg gcagcatggc caacggtcac ccatatgcgt
    50641 aactttgaga acgttcgccg caccggtgat gtgatcaacg agtccattcg ttatttcagc
    50701 cagcagtaca tcgacatgcc gattactcag gcgctgattg atgcactgac ggagtcggtc
    50761 aacgcctacg gtcgcaaaat gactggtgat ggtgcggtac tgggcttccg ttgctggttt
    50821 gatccggccc gcaatccgga gacggagctg gccgccgggc acctgttgct gagctacaaa
    50881 tatacgccac caccgccgct ggagcgactg acgtttgaga ctgagatcac ctcggaatac
    50941 ctgttaaccc tgaaaggggg caactgatgt caaagattga gataaaccgc atcacgaatg
    51001 ccaacatcta tctggatggt actaacctgc tgggacgggc tgaggaagtt aaactccccg
    51061 atgtctccat gattatgcag gaacacaagg cgctggggat ggtgggtaag gtggaactcc
    51121 cggctggttt tgacaaactg gaaggcgaaa tcaaatggaa cagcttttac cgcgatgcga
    51181 tgctgtctgc cgcgaacccg tacaggtcgc tggcactgca gtgtcgttcc agcgtccagc
    51241 gctacagctc gcaggggctg attgacgaaa tcccgctggt caccttcctg acgattatgt
    51301 tcaagaagaa cccgctgggg acgttcaaac agcacgagaa cgccgagttc tccagtagct
    51361 tcacctgcac gtatatcaga caggtactgg atggtgaaga gctgctgcaa ctggactatc
    51421 tggccaacat cttccgggtc ggcggtgttg atcaactgac tgactaccgt atcaatatcg
    51481 ggggctgacg gtgagtgttg aactgacgga taaaggagga cgatgtgcgg cactgggcat
    51541 gtcaaatggt acgtggttta ccctccttga tattccgggg gtggaaaccc tttttaatac
    51601 ccgtaaaacc aatgacccga ttgactgcac acgttcaaag gcccgcaaac tggcggattt
    51661 gattgaagca tgggagcctc ccgaccactg gttctccggc atcggcaaat ctgagggaaa
    51721 gacgcttctc atcgctttcc tgcgtaactg caaggggttt cgcacttgct gacatcacag
    51781 gggctccggc cccttcttct taatctcctt taatatccgt cacgcgcttc tcccgacata
    51841 ctgccctgaa cttacacagg agcacaatca tgtcacagac cccatccgat acttttaaat
    51901 tgtcttatcc cttcaccact gctgcaggca ccagaattga gctggttgaa ctgaaacgcc
    51961 tgacggtaaa agacctgaag caggtgcgca aaatcagcaa aaacccggca gactgggacg
    52021 aaccgctgat tgcccgcagt actggtcttc tcccggagga tctcgacaat atggatctgg
    52081 ctgattacct gcagttacag aaacgatttc agctcatcac ggggatgggt gagagcaacc
    52141 agggcgctga cgcaggcgca ggggctgctg gcgagatggt tccggtttca gccgggggag
    52201 attgatgccc tcgatactga cgatctggag atgtggctgg agcaggctga agagcaaatc
    52261 aaaagcgagt acggcgacaa atcatagtac agacagccgc cagtagcggc tgttctgcgt
    52321 tatcccctca cgtcttttca ccttccccgg aggttaacca ctatgtcggg acagttttca
    52381 gtcggcgttg ttatcggcgg gatgattggc agcacattcc gttctgcaat gagcggtacc
    52441 cgccgtgcgc ttgattccct gagcgatacc tcacgccgcc tgcaggaacg tcagaacgct
    52501 ttaacccgtg caacagaacg ttatggtcaa ctgggttctt cccggatgca gcatctcaac
    52561 agcgagctgc tgcgggtaag ccgcaccatg gagcaaattg agcgccagca gcgccgtctg
    52621 tcagcggcat ccgctaccag tgatgcgctg aaagctaacc gcatggcgct gtatggtcag
    52681 gggattgaag cgtatggcat ggcacagact gtttatcata cggtttcccc tgccgttcag
    52741 cagtccatgt cttttcagga caaaatgatt gatatgtcga tcaccgcaaa atatgacaat
    52801 aaaacgcggg atgcacttgc cggacagata aaaggctggg cgcttaaata caatcagtat
    52861 caggatgagc tgcaggaggc gatgggttca ctcatcagcg acaatattga taatgtgtca
    52921 gatatcggtt ttctgatgcc ggatattgcc cgcgcggcaa cggcaacacg cacgtctgct
    52981 caggactggg caaaagtggc cgcagtctgg caaaactccc tgaaaggcgc ggccagagat
    53041 tttggtgccg ttcagaatat tatggcttat gccggtgacc aggggtcatt tgaaatcccg
    53101 gatcaggtca agtggatgca gtccctggcc ccaatgatgg cgggtattgc cagtggaaaa
    53161 gaggctgttg ctgaaatcgg ggccagtctc cagatagcaa aaatcggtgc aggttccacc
    53221 gacgaagcag ccaataattt taaaaacttt cttaccaaaa tttttgcccg cgatactcag
    53281 aaacagtttg ctgatctggg tattgatttg cagggatcta ttgcgagtta taaagctgcg
    53341 gggatctctc cgattgaagg gatgttgagt gttatagaac gttacctcaa tgccaaaagc
    53401 cccgaagcgc tggccggctt caaatcagcc atgaaaataa agaatgatac ggcaagagat
    53461 gaggcacttc aggctctggc gaaaaacttt ggtctgggcg atatgttcgc ggatatgcag
    53521 gtcatggcat ttatccgccc gatgctggcc aacatggaca gatatcgaga gatccgtgcc
    53581 ggtgctctca gggctgcgga taacgatttg cttgccagtg cttatgatca gcggctgaaa
    53641 tctccccttg aagccactaa aacacttatg gtcagcagtc gcgatctggc aattacgctg
    53701 ggcgatcaat tagctccatc ttttatttct ctgactcagg acttgctccc actcattcag
    53761 gggacaaaac actgggtggc gactcacccg caatttgtca gtggggcttt taagctcatc
    53821 agtgcgctcc ttgcgattaa gatagcgact gttggtctca aactggggct gaatctcctt
    53881 atttccccct ttgtgaacgt ctggaaaact gctgttttac tccggaccaa ctggcatcga
    53941 ctgactaccg cactcggaga aggtggcaaa ttacgctggc ttgtcactgg attcagccga
    54001 ctgaccagcg gaggactgaa actcagcaaa gttctggcgg gcagcctcgt tcgcggtttt
    54061 atgagcgctg cacgtgccgt tctctggatt gggcgagcgc tgatgatgaa tcccatcggt
    54121 ctcgttatca ccgctgtcgc ggcagcagct taccttatct accgcaactg gggggcagtc
    54181 agtggctggt ttaaacagcg ctgggctgac attcaggaag cctttaacgg cggtatcgcg
    54241 ggaactggta agctgctgat taactggtcg ccggcaggcc tgctctataa agcctttgcg
    54301 gctgcgctga aatatttcgg cgttactctg ccggcaaagt tcaccgactt cggtggccat
    54361 cttatcgacg gtttgattaa cggtatcaaa aacaaatggg ggtcgctcaa atccagtgta
    54421 accggaatgg gtgacagcat cagtagctgg tttaaacaat gctgggctga cattcaggaa
    54481 gcctttaacg gcggtatcgc gggaactggt aagctgctga ttaactggtc gccggcaggt
    54541 ctgctctata aagcctttgc agctgcgctg aaatatcttg gtgttgatct gccggcaaag
    54601 tttaccgact tcggtggcca tcttgtcgat ggtctgatta acggtatcaa aaacaaatgg
    54661 gagtcgctca aatccagtgt aaccggaatg ggcgacagca tcagtggctg gttcagcgaa
    54721 aagctgggca ttcattcgcc gagccgcgtg tttatgggct ttggtgacaa tatcgcgcag
    54781 ggggccgcca ttggcctgca gcggaccact ccgcttgcag ctctggccgg gcagcgaatg
    54841 gccagtgaac tgctccccag aatgcccgtg agcattcagg ggccagaaat acgggataac
    54901 acttcaggtg ttcgcttcag tatgccgttg cccgatatca atgggtttat gtcgtctgct
    54961 aaaaatgcga tcggagccgt aatcaatagt ttgtcttcca tgcccgctat tccgctctcc
    55021 acccgggcat cgattttacc agggcaacgt ctggcaaatg agatgacacc ggatgttccc
    55081 cgtatcccct cgcctgaaat cctggctgcc ggatattcag gccgtggtgc agctgcaacc
    55141 ggcggtggaa cgtctggtgg tatccaggtc agctttaatc ctcagttttt cctcaatggc
    55201 agggaaacca cagcgcctgc aggactgact ggtgccctga atatgagtct gcatgagctg
    55261 gaaaaaatgc tggagcgtct gctggctcag aaacaacgta aggagtaccg ctgatgtttg
    55321 ccgtactggg tgatattgag tttgagctga ttacctactg ggacggcttc gaggccacgt
    55381 tcggcgtcga ttatgcggag catgcccgca tcgggggtaa gcctggtctg cagttcgtcg
    55441 gcgacaggct ggacgaaatc cagataactc tggttttcca tcagcattat tgtgtacccg
    55501 atgtggagct ggcgagactg cgaacagcca tgaaagccca tcaggcactg gcgctggtct
    55561 tcggcaacgg tgactatcgc ggctggttcg tgatcaccga tgtgactgca accagcgagc
    55621 agactgacag taccggcaac gtgctggctg tcagtgccac cgtgtctctc cgggaataca
    55681 ccggtgaccc gaaaaatcct ctgcaaccac cggcaatacg cacgaagctc ccgggtgtcg
    55741 gggcggtctc cggtgccata ccttcacctt caggggtggc gcagttcatc cgcaacggcg
    55801 tcaactatgc gaaacaggcg cagtctgtac tccagaccac tatcagcgcc gttcgggtga
    55861 cacagaaaat gaaggataac cccgttgtcg cactgacccg tgtgccgggg ctgatgagcg
    55921 gactgggtaa tatctccggg gctctgggga aaagtgttcc ggcgtttaac gcactctctg
    55981 aatccatgcc cgatgccatc agtctggcca gaacagccag cgaagcagcc acgtatgtac
    56041 agcaggcaca gtctgcgctg agtggtgtgg acaaaagaaa tattgcaggt gctctggata
    56101 ccgtttccgg gcagcttaac gccgtcggca cagcattcaa ccgcatgtct ccgggattaa
    56161 gtgcaatggc cgccagaata ctgacgagga gtgtgtgatg tttcttgaac atgttacccg
    56221 tgacggagag cgctgggatt cgctggcatg gcagtactac ggtgacccgc tgggctatcc
    56281 ccggattatt gccgccaatc cgcacgtggc catcacgccg gtgctgccct ccgggctgtt
    56341 gttactgatc ccggtgattg aggctgaaga agcccgtaca gaagaggata ttgccccatg
    56401 gctgagataa acagcactgc gcaagtcaca tcagcgttaa ccggcgtcag cgatgtgctg
    56461 acaccggtgt tcactctgtg gtatctgcag aaaaacatca cctctgatat cgcgccttat
    56521 gtcacccgtg tgacctggag cgataacatc aaaaatgagt ccgataccat tgaggtggag
    56581 ctggacgaca ccgatggccg ctggctggat aaatggtatc cgggcaaggg tgacacgctg
    56641 acgctgaaaa tgggctatca gggcgagaag ctgctgtcct gcggtacgtt ctctatagac
    56701 gagatcgaag tgagttcgcc cgcttccgtt gtttctatcc gtggggtggc cacctcggtt
    56761 aacagtgccc tgcggactaa aaccagtcgt ggttttgaga acaccacgct ggcagctgtt
    56821 gcggggcgga ttgccagaaa gcaccggctg aaactggtgg gcagcattga gtccatcaga
    56881 atcgaccggg tgacccagta tgctgaaacc gacgtgggtt ttctgcgccg gctggccagc
    56941 gagtatggtt atgcagtgaa agtggtcagt gaccagctga ttttttctca tctggccaca
    57001 ctgcgcagtc aggagccggt caggcagtta aaaccgcagg atgtggcccg cttttccctg
    57061 cgtgacacca tcaaccgggt ctataaatct gcaaaggtaa aacaccagaa aagcagcagt
    57121 aaaaaactga tcgtctacga agctgatggt ggtacccgtg aaagcgacaa aaagctcaaa
    57181 ggtggtaagg ttaccagcgc tgactcactt aaagttaaca gccgcgtcag cgacccggac
    57241 agtgcccgga ttaaagcgga ttcagcactg gccagacata acgaatacca gcagaacggc
    57301 tccctgacgc tgacgggaac acctcaactg acagcaggca acaaaattga actggtgagt
    57361 tttgggcagt tatccgggcc atggctcata accactgccc gccatgcgtt tgaccgtaac
    57421 agcggctaca ccacagagct ggaagtggca cgggggccag tcacaagagg gaaaaaacaa
    57481 aaaactcaga aactcacggt ttatcacccg gatggcagta catcgacggt gattaaggag
    57541 aagaaaaaat gactggtgtc actcgtcagg tcggtacggt cagtgccgtt gatgccgaca
    57601 gggttcaggc ccgcgttcgt ctgcctgaat gcgataacct gcgcacaaac tggcttaacg
    57661 tgctgcagcg caatacccag gataacaaag attactggct ccctgacgtg ggggagcagg
    57721 ttgaggtgct gctcgatgcc aacggcgagg atggtgttat tctgggcgcg gtgtattcag
    57781 acgtcgataa accaccgttc agtgacaaaa atatccgggg aacccggttt gctgatggtg
    57841 cagagtacag ctacaaccgg aagacgcaca ctctgatcat ccggggcggc attgagcata
    57901 ttgtcattga gtgtggtgct gatgtggtat tgaaaacaca gaaagccacg attgacgcac
    57961 cggaaaccga acttaccgga gatctgcgtg tcaggggtaa gctgatttac gaaggaggca
    58021 tggcgggttc tggtggtgaa ggtgttaccg cgaccatcca tggcaatatc gagattaaag
    58081 ggaatgtcca tgccacgggc agtatgttgt ctgatggcga aaactccagc caccactccc
    58141 actgagcttt ttaaacgcct ttaatatcag cgttcccgca cgggggcaat actgccccca
    58201 tgaaaacaac ctcagtattc tggcaaccag ccctgcaggc tcccggcgaa attgtccggg
    58261 ggctggatga tatccggcag gcgattcaaa ttatcctgcg gactccccgc ggcagcgacc
    58321 cgcatcgccc ggagttcggc agcaatctgc atctttatat cgactggcct gtagaccggg
    58381 ccattccgca tgtggtgcgc gaatccgtcg atgccatccg gcgctgggag ccccgctgcc
    58441 agcttatgtc agttaaaccc gccgtcgacg gcgaacatct tacgctccgg gtgagctgga
    58501 aaggctcaga cggacagacc cggactcagg agctgctatg gcgctgacag aacccgattt
    58561 tattgaacgc gatgccgaca aaatcacggc agaaatgatt gcgaagtatg aagcggatac
    58621 cggcaaaacg ctgtacccgg cacaggcaga acgtctgctg attgatctgt gggcctatcg
    58681 cgaaatgctg gtcagggttg cggtacagga ggcagcaaag cagaatctgg tcgcctttgc
    58741 ccgtgagccg atgattgatt acctcggtga actggtcggt gtataccgtc ttgccgcgca
    58801 gcctgccacc accacgctcc agttctccgt agatgaggca ctggccattg atgtgctgat
    58861 cccggcaggc acccgcgtca gcgcttccga cagcgttatt tttgccaccg atacagatgt
    58921 ggtactgaag gccggattgc tgctggtcaa tgtcacggcc acctgtaccg aacccggtac
    58981 cgctggtaac ggctggcaac ctgcgcaggt cagtcagtta ctcgatgaga ttgataacgt
    59041 taacctgctg gtgagcaatc tgatggccag ttccggcggt tcagaacagg aagacgatga
    59101 caggctccgg gagcgtatca ggctggcccc ggagtcattc accaatgccg gaagccgtgg
    59161 cgcataccgc tttcatgcca tgcaggccca tcccaacatt gtcgatgttg ctgtgctttc
    59221 cccggttccc gggaccgtag atctgtatcc gctgctcagt accggtctgc cggacggcgg
    59281 tgttctcacg ctggtagaga gtttctgctc tgatgagaaa gtcaggccac tcactgatac
    59341 agtgcgggct aaaacaccag tgaaggtgga ttacaccatt gaagccagga ttacgatcta
    59401 tcgtgatcag gatgccaggt ctgtaaaaga tgccgctaac agcgccatac agaactgggt
    59461 ggcatcacgt gccgccacgc tggggcgcga tattgtcccc agccagatta tcagtgcatt
    59521 gtccgtttcc ggggtgtacc aggttgaact ggtgacaccg gcactgcggg tggtggcaga
    59581 aaacgaatgg gcaaactgta cggcaatcac tcttaacatg actggagtgt ctgatgactg
    59641 agccattaca actcccgcca ccgcttgagg gtgatatcag tctcaggacg ctgggaagac
    59701 tggcaggacg gctggataac atcgacctga gcgtactgat ggtctttctc gtcgatatcg
    59761 tcgacagttc cgcgctgcca tggctgggcg agcagttctc actgtctggc gatggctggg
    59821 agctggcgga atcggacgat gttcgccgca tgcttataaa agcagccatc gaactgcacc
    59881 ggtataaagg gacgccgtgg tcaatccggg aagttatccg ccgttttggc tttggtgaag
    59941 tggatctgat tgaaggcaca ggtcgtctca gttacgacgg caatcgcagc tataacggac
    60001 tgtttgttca tggagatgca gccgcctggg cagtttatcg cgttattctg aaacagccca
    60061 ttactaacga tcaggccgcg atgctgcgtc agacgctggc tgcatttgca ccggcccgct
    60121 gccatctggc cagcctggag tatcagtctg tggccattcg ctataacaat accgccatcc
    60181 atgatggcag ttataaccac gggagcagtt gattatggga aacctgaatg aaacagaaaa
    60241 gtgggaagaa aatatctatc aactggagac atcagatccg gttctgggtg gtgcagacgg
    60301 gatatcaaat cgagcccccc ggcaactggc aaacaggacg aaatggctga agaagaaaac
    60361 ggaggaagcc gcacagtcac tggctgaaca cgtacgttcc cgtaaccacc cggacgcgac
    60421 actgacagct aaggggttca cccaactgag cagtgccacc aacagcacct ctgaaacgct
    60481 ggccgccaca ccaaaagcgg tcaaggctgc atacgacctg gcagccggca aggcgcctgc
    60541 cagccacact cacccgtgga gtcagataac gggagtgcct gcggcttcac tgacggcaaa
    60601 aggcaccgta caactgagca gcgccacgga cagtcaatca gaaactgagg ctgccacgcc
    60661 gaaggcggtc aaggctgcat acgaccttgc agccggcaag gcgcccgtca gccacactca
    60721 cccgtggagt cagataacgg gagtgcctgc tgcctcgctg acggcaaaag gcaccgtaca
    60781 attgagcagt gccatcaaca gcacgtctga aatactggcc gccacaccga aagcggtcaa
    60841 ggctgcatac gatctggcaa acggaaaaca accggcagat gccacgctca ctgctctggc
    60901 aggacttgcc actgcagcag atcggttgcc ttattttacc ggagcagacc gcgcagagct
    60961 ggcaaccctt acagctattg gtcgcgctat tatcgctaag ggcagtataa aagatgtcct
    61021 caattacctt ggtttaggag aaggctcggc gctacccgtt ggtgtgcctg ttccgtggcc
    61081 cac
//
LOCUS       DAPOXO010000020        58597 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPOXO010000020 DAPOXO010000000
VERSION     DAPOXO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 58597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.020"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(168..1832)
                     /gene="glnS"
                     /locus_tag="ROH59_001559"
     CDS             complement(168..1832)
                     /gene="glnS"
                     /locus_tag="ROH59_001559"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HDX4804066.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(2052..2813)
                     /locus_tag="ROH59_001560"
     CDS             complement(2052..2813)
                     /locus_tag="ROH59_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4804067.1"
                     /translation="MKGYNRLEQIMDYLKSHNLVTVDELVAVTNASPATIRRDLIKLD
                     EQGVISRTHGGVTLNRFIPTQPTTHEKMQRSLAEKHAIASAAASMVKAGDSVVLDAGT
                     TMIELARQITHLPLRVITSDLHIALFLAEFKQIEVTIIGGRIDDSSQSCIGEHGRKLL
                     QNTWPDVAFLSCNSWDLEKGITAPTEEKAALKRDLIAHASRKILLADSSKYGSWSLFN
                     IAHLNELTEIITDSQLDGQTRRTLASLSTRLIIAD"
     gene            complement(2815..3801)
                     /locus_tag="ROH59_001561"
     CDS             complement(2815..3801)
                     /locus_tag="ROH59_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-threonate 4-phosphate dehydrogenase"
                     /protein_id="HDX4804068.1"
                     /translation="MNNIIAVTMGDPAGIGPEIIIKSLSEAGLAGAPVVVVGCVRTLR
                     RIMAMNITPQAELRVIQKVCDAHFAPGVINVMDEPLANPDALTPGVVQAVAGDLAYRC
                     IKRATALALSGEVKAIATAPLNKEALHLGGHNYPGHTELLAHLTGSKEYAMVLYTEKL
                     KVIHISTHISLRKFLDTLNGERVKTVIRVANHFLKRVGIERPRIAVAGVNPHAGEHGL
                     FGTEEIEIIAPAIEAMQAEDIDVTGPCPPDTVFMQCHEGLFDMVVAMYHDQGHIPLKL
                     LGFYDGVNITAGLPFIRTSADHGTAFDIAWTGKAKSESMAVSIQLAMQISRE"
     gene            complement(3794..5029)
                     /locus_tag="ROH59_001562"
     CDS             complement(3794..5029)
                     /locus_tag="ROH59_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HDX4804069.1"
                     /translation="MEKGITKPSILIVADDFTGANDAGVSLAQVGHTVDVAFEMPYRG
                     DASVWVINSDSRAMDPKLAAMKITSLMSHLPLANNPPLVIKKIDSTLRGNIGAEIEAL
                     MKACGITGAVVAPAFPQAGRTTVAGECWVNGVRITETEFASDPKTPVLSARIADIIRL
                     QTAIPCQPVTVSQLSHLSYEQPWIGVIDAQTDSDLDRIAAAVMQAKQPLLLVGSAGIC
                     DAVARRSAIMPPPTVLAIIGSMSEIAQRQIATLHSHPRITQIYVDVEHILAGNASDYD
                     ARIVQALQKGDHCIVHTCNDSVARHQIDTLCQRWQMSRAALGEKICRFLGELTRQVLL
                     CAMPDALYLSGGDVAMATASALGATGFRITGKVAQCVPYGHFLGGVWSRSVMTKAGGF
                     GDETTLHQVLNFIEEKRSE"
     gene            5199..6356
                     /locus_tag="ROH59_001563"
     CDS             5199..6356
                     /locus_tag="ROH59_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDX4804070.1"
                     /translation="MVIINSTILSGAGAIPSLTSLLPDIRKMLLVTDRNIAQLDGVQQ
                     IRALLEKHCPQVNVIDNVPAEPTHHDVRQLMDALGDASFDVVVGIGGGSVLDVAKLLS
                     VLCHPQSPGLDALLAGEKPTQRVQSWLIPTTAGTGSEATPNAILAIPEQSTKVGIISQ
                     VLLPDYVALFPELTTSMPAHIAASTGIDALCHLLECFTATVANPVSDNAALTGLSKLF
                     RHIQPAVNDPQDLRAKLEMLWASYYGGVAITHAGTHLVHALSYPLGGKYHLPHGVANA
                     ILLAPCMAFVRPWAVEKFAQVWDCIPDAETALSAEEKSHALVTWLQALVNQLKLPNNL
                     ADLGVPPEDIASLSEAALNVKRLMNNVPCQLDLQDVQAIYQTLFPQHQFKE"
     gene            6360..7247
                     /locus_tag="ROH59_001564"
     CDS             6360..7247
                     /locus_tag="ROH59_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDX4804071.1"
                     /translation="MPKTIEGVLTAIVTPFTATGSLNIPALKVQVNRQLEAGNAIFCG
                     GTNGEFFVLNEQEKLSVTQTCVDEVAGRAPVVAHIGEISTRETIRLGQQIEKLGVDAV
                     SVIAPYFVPLKQEELIAHYSAIADTLSIPMFLYNIPARTGNTIQPETARALASHPNII
                     GIKDSDGSDESLKGFLDAVRDIDGFNVLNGPDSLIHKGFVEGCSACISGLANVAPREI
                     NAIWSRFHAGDIEGSYEAQESVTGLRTDLYKVAFSPAAVKKALQLMGHDVGDSRYAVN
                     FTPEQISEIQQIIRHYNIN"
     gene            7307..8065
                     /locus_tag="ROH59_001565"
     CDS             7307..8065
                     /locus_tag="ROH59_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDX4804072.1"
                     /translation="MFLWFMQPDIWLTLITLTFLEIILGVDNIIFLSLVVAKLPLSQQ
                     NMARKLGLSCAMIMRILLLISIAWLSHITQPLFTVLTLEISFRTLILLGGGLFLIYKA
                     IQEIREELSPAQEDEHGSGSRQLSLCGAIVQIMLLDIVFSLDSVITAVGLSQHIFIMI
                     AAVMIAVGVMMFAAKTIGDFVNATPSIKILALTFLLFVGVLLVADSLNIHIAKEYLYF
                     AIFFSLSVETLNIIRERKNKKVSTLIETHESHSH"
     gene            8101..9270
                     /locus_tag="ROH59_001566"
     CDS             8101..9270
                     /locus_tag="ROH59_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000109428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HDX4804073.1"
                     /translation="MSVALIRDGVIRPSENDSHVLTAMLPSSCPQNHAANILPLPDGA
                     LMCVWFAGTQEGIADISVWGSRLPAGGMQWSDAAKLSHDDTRSEQNPVLFLAPDNVLW
                     LLWTAQISGNQDTAIVRYRKSDDLGQTWGEIATLLDKPGTFIRQPITVLDNGNWLLPV
                     FYCRTQPGEKWVGNDDISAVKISADGGHSWRDVEVPQSLGCVHMNITMLHDGTLVALF
                     RSRWADNIYISHSVDNGESWSVPQATELPNNNSSIQVTTLASGELALVYNAMSAAGAV
                     ERRASLYDEIDDGDDSRKEPTAVGRSAFWGAPRAPMTVAISADGGKSWSWRRNLDEGD
                     GYCMTNNSLEKLNREFSYPSIKQSPDGTLHIAYTWWRQAIKYVRISPEWVKGQAS"
     gene            9267..9737
                     /locus_tag="ROH59_001567"
     CDS             9267..9737
                     /locus_tag="ROH59_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDX4804074.1"
                     /translation="MIIGNLNHLSLAGLPAWVRNILLRPECSLSALSTREDGRWQPEG
                     CRWFCSLGTSDTQPAELRHTEYHHLWADIQVVITGCEGINAGTRPIARENDEERKPDL
                     FIAPSPENSVAITLHAGDFAVFMPEEPHQALCAIGTATSIRKAVFKVPRDMLEA"
     gene            9751..11031
                     /locus_tag="ROH59_001568"
     CDS             9751..11031
                     /locus_tag="ROH59_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HDX4804075.1"
                     /translation="MTMEMILALGILVLMIVLIMSDKMPFGAPPLLACLLLVVSGLST
                     VQQAFAGFVNPSVVMIAGFMVVMAALQKTRLISNVKSAMISLVNKGSYRSYGLLLVIV
                     MLGASLAGTGATGYYVLILSLVSTIPYSKKLPTSKLMMPLGFATNHPLLPINLALLFG
                     VTATVLETAGFHQAISMGRFALVNLIMSAAFLAWSLIAYRFLPDHPIADASEDALAAR
                     EETFNALPAWKEYCTIAAFAVSVIGMMLMNILGNIAFVIPGLAGAFVLMIDVLDFKEV
                     RDHMGAPVILMMAGVIGVADALAGTGFTAMVGDAVAGVLGSGVSPFVFIVAFALLTST
                     CATFTGSNMGSVYIFAPIAIAACTSLGLNPTAAAIAVVISGWNGGYMPIDGMPAMILG
                     MGKYKLPEFWVFSVPMYLIRILALCAGAVFIFPM"
     gene            complement(11120..13066)
                     /gene="nagE"
                     /locus_tag="ROH59_001569"
     CDS             complement(11120..13066)
                     /gene="nagE"
                     /locus_tag="ROH59_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HDX4804076.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVVFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLNQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVVDSARVNDAMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAEATPATAAPVAKPQAVPNAVSIAELVSPITGD
                     VVALDQIPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDD
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            13399..14199
                     /gene="nagB"
                     /locus_tag="ROH59_001570"
     CDS             13399..14199
                     /gene="nagB"
                     /locus_tag="ROH59_001570"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDX4804077.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            14259..15407
                     /gene="nagA"
                     /locus_tag="ROH59_001571"
     CDS             14259..15407
                     /gene="nagA"
                     /locus_tag="ROH59_001571"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDX4804078.1"
                     /translation="MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     ENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITRTIVNGNEVVTQ"
     gene            15416..16636
                     /gene="nagC"
                     /locus_tag="ROH59_001572"
                     /gene_synonym="nagR"
     CDS             15416..16636
                     /gene="nagC"
                     /locus_tag="ROH59_001572"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HDX4804079.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            16684..17436
                     /gene="nagD"
                     /locus_tag="ROH59_001573"
     CDS             16684..17436
                     /gene="nagD"
                     /locus_tag="ROH59_001573"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HDX4804080.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
     gene            17692..19356
                     /gene="asnB"
                     /locus_tag="ROH59_001574"
     CDS             17692..19356
                     /gene="asnB"
                     /locus_tag="ROH59_001574"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HDX4804081.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFEAYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
     gene            complement(19398..19835)
                     /locus_tag="ROH59_001575"
     CDS             complement(19398..19835)
                     /locus_tag="ROH59_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804082.1"
                     /translation="MLRFMTALMGALLLMQSAFADTVKPEIGKYVFGYRGQEGAVVWM
                     MRIGPKASNEALIQVSHVDNDIDGQIFRCKVKALQEGEKSYTAVIKGKSFELLRLKEG
                     NGRLHIPDEQATWLVAYSDELSNSDVANPEHFLTAYQNQQAPQ"
     gene            20169..20245
                     /locus_tag="ROH59_001576"
     tRNA            20169..20245
                     /locus_tag="ROH59_001576"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20203..20205,aa:Met,seq:cat)
     gene            20256..20340
                     /locus_tag="ROH59_001577"
     tRNA            20256..20340
                     /locus_tag="ROH59_001577"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20290..20292,aa:Leu,seq:tag)
     gene            20364..20438
                     /locus_tag="ROH59_001578"
     tRNA            20364..20438
                     /locus_tag="ROH59_001578"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20396..20398,aa:Gln,seq:ttg)
     gene            20473..20547
                     /locus_tag="ROH59_001579"
     tRNA            20473..20547
                     /locus_tag="ROH59_001579"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20505..20507,aa:Gln,seq:ttg)
     gene            20563..20639
                     /locus_tag="ROH59_001580"
     tRNA            20563..20639
                     /locus_tag="ROH59_001580"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20597..20599,aa:Met,seq:cat)
     gene            20688..20762
                     /locus_tag="ROH59_001581"
     tRNA            20688..20762
                     /locus_tag="ROH59_001581"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20720..20722,aa:Gln,seq:ctg)
     gene            20800..20874
                     /locus_tag="ROH59_001582"
     tRNA            20800..20874
                     /locus_tag="ROH59_001582"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20832..20834,aa:Gln,seq:ctg)
     gene            complement(21029..22204)
                     /gene="ubiF"
                     /locus_tag="ROH59_001583"
     CDS             complement(21029..22204)
                     /gene="ubiF"
                     /locus_tag="ROH59_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HDX4804083.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFTVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVVFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPTSLTALHRHNDLQELELKGGETILAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPARIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLIRRHAL
                     QYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFMMQSGMDLFYAGFSNNLPPLRFVRNLGLMAAERAGVLKRKALKYALGL"
     gene            22350..23774
                     /gene="miaB"
                     /locus_tag="ROH59_001584"
     CDS             22350..23774
                     /gene="miaB"
                     /locus_tag="ROH59_001584"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDX4804084.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            23927..24967
                     /locus_tag="ROH59_001585"
     CDS             23927..24967
                     /locus_tag="ROH59_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415193.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDX4804085.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESV
                     PEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREEQEQK"
     gene            24964..25431
                     /gene="ybeY"
                     /locus_tag="ROH59_001586"
     CDS             24964..25431
                     /gene="ybeY"
                     /locus_tag="ROH59_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDX4804086.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEAIETEIMLALGYEDPYIAEKE"
     gene            25521..26399
                     /gene="corC"
                     /locus_tag="ROH59_001587"
     CDS             25521..26399
                     /gene="corC"
                     /locus_tag="ROH59_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HDX4804087.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            26424..27962
                     /gene="lnt"
                     /locus_tag="ROH59_001588"
     CDS             26424..27962
                     /gene="lnt"
                     /locus_tag="ROH59_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HDX4804088.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSTAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYVQWFTPQP
                     EKTIQVSMVQGNIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLITGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSLNGIQLTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYSRTGNWPLWVLTALFGFAAVLMSLR
                     ARKR"
     gene            complement(28089..29966)
                     /locus_tag="ROH59_001589"
     CDS             complement(28089..29966)
                     /locus_tag="ROH59_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDX4804089.1"
                     /translation="MSASSVKPLNVQLPAITLILFALCVGIFCYLAQWMSYEEVDQSA
                     LIHLGANVASLTLSDESWRLLSSVFLHSSFSHLLMNMFALLVVGTVAERILGKWRLLI
                     IWLFSGIFGGLISACYALRESEQIVISVGASGAIMGIAGAAIATQLASGAGTHHKNQR
                     RVFPLLGMVALTLLYGTRQTGIDNACHIGGLIAGGALGWLSARLVGQNRLVTEGGIIV
                     AVTLLLTGTIWLVQQQIDESVLQVRQSLREAFYPQEIEQERRQKKQQLVEERNALRET
                     LSAPVSREQASGDLLAEIADIHDMAISRDANTLYAAIENTNSIVVFDLGQKKILHTFT
                     APIAKEKSVKHCGGCKDQGVRSLALSPDETLLYATSFEANALSVINVATGEIIQSITT
                     GAHPDSLILSRDGTKAWVMNRTSNSVSAIDLVAYQHVADIPLEKYDGTGMSGKPGAWV
                     MALSPDEKTLLVPGAGRGNIVRINTITHQKEDFPAGDARGVVSAMGFRPKNGEIIFAD
                     SQGISRIRAEDQQASIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILLNINAGQ
                     IIGVYPASYVNHLRFSADGRKIFVMAKNGLIQLDRESSLDPQAIIRHPQYGDVACIPE
                     P"
     gene            30420..31328
                     /gene="gltI"
                     /locus_tag="ROH59_001590"
     CDS             30420..31328
                     /gene="gltI"
                     /locus_tag="ROH59_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HDX4804090.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPAAGNTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNAERQKQAAFSNTIFVVGTRLLTKKGGDIKDFADLKGKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            31498..32238
                     /gene="gltJ"
                     /locus_tag="ROH59_001591"
     CDS             31498..32238
                     /gene="gltJ"
                     /locus_tag="ROH59_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HDX4804091.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAFIMLVMTLVERKVRLPGNMGGK"
     gene            32238..32912
                     /gene="gltK"
                     /locus_tag="ROH59_001592"
     CDS             32238..32912
                     /gene="gltK"
                     /locus_tag="ROH59_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HDX4804092.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            32912..33637
                     /gene="gltL"
                     /locus_tag="ROH59_001593"
     CDS             32912..33637
                     /gene="gltL"
                     /locus_tag="ROH59_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HDX4804093.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDS
                     PKDAFFDNPKSDRAKDFLAKILH"
     gene            33755..34690
                     /gene="rihA"
                     /locus_tag="ROH59_001594"
     CDS             33755..34690
                     /gene="rihA"
                     /locus_tag="ROH59_001594"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HDX4804094.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVASGAVKPLMRNLIIADNVHGESGLDGPALPEPAFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            34774..36444
                     /gene="hscC"
                     /locus_tag="ROH59_001595"
     CDS             34774..36444
                     /gene="hscC"
                     /locus_tag="ROH59_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HDX4804095.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVNASAGDNFLGGEDFTHMLVDEVLKRA
                     EVAKTTLNDSELAALYACVEAAKCSNQSPMHIRWQYQDEMRKCEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRNEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGTYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASDYLAIEIP"
     gene            complement(36504..37955)
                     /gene="djlC"
                     /locus_tag="ROH59_001596"
     CDS             complement(36504..37955)
                     /gene="djlC"
                     /locus_tag="ROH59_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HDX4804096.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLARLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAATEHEILRVFRALLDSENDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAIAIEARYLSLNCASLLAERLNWHSFNDCEGIDEEEREAFLEAI
                     QAGDCFDFLSLLEYPVALQNQTVEYYFSLERCCRYHPDYVTAFLAMEGPWFIPDDAKL
                     HRKLLRWYSSVQTGMAELIPVAQQWQAEEPESEDARYYQCAQRLYCGEGESLLADLCA
                     YRESYPSTQADNLLLQWSKRHCPDYFALLVMVIEARSMVDAQGKPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEQDSPLLDLYRVAEQVVL
                     EAFPKQEMLARLDARLERGEAHPLETIITRMLLTKVKLEPEDEDVDEPTPENHEEIND
                     EDEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(37952..38659)
                     /locus_tag="ROH59_001597"
     CDS             complement(37952..38659)
                     /locus_tag="ROH59_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDX4804097.1"
                     /translation="MNKEEQYLLFALSTPMEILNQGCKPAHDSPKMYTGIKEFDLSSS
                     WGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSSPEEWKALIAGGSERGLIYTQFV
                     AQTAMCCGEGGIKAWDYVRMGFLSRVGVLNKWLTEDESLWLQSRVYIRAHHYYHSWMH
                     YFSAYSLGRLYWQSSQCEDNASLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQP
                     LTVQPECPVTLKDVSDL"
     gene            38761..39315
                     /locus_tag="ROH59_001598"
     CDS             38761..39315
                     /locus_tag="ROH59_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDX4804098.1"
                     /translation="MNKKLMYIFAIFIVAAITCISQPKKTTLRDKAMANYAFDYLSSP
                     GSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRA
                     QSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQ
                     KWLKLAAKQHYKNAERLLAGLSAH"
     gene            39455..39790
                     /locus_tag="ROH59_001599"
                     /pseudo
     CDS             39455..39790
                     /locus_tag="ROH59_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706566.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
     gene            complement(39860..40342)
                     /locus_tag="ROH59_001600"
     CDS             complement(39860..40342)
                     /locus_tag="ROH59_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HDX4804099.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            40577..43159
                     /gene="leuS"
                     /locus_tag="ROH59_001601"
     CDS             40577..43159
                     /gene="leuS"
                     /locus_tag="ROH59_001601"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDX4804100.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEY
                     KEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            43174..43755
                     /gene="lptE"
                     /locus_tag="ROH59_001602"
     CDS             43174..43755
                     /gene="lptE"
                     /locus_tag="ROH59_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HDX4804101.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            43755..44786
                     /gene="holA"
                     /locus_tag="ROH59_001603"
     CDS             43755..44786
                     /gene="holA"
                     /locus_tag="ROH59_001603"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDX4804102.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAA
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMSEALNRLSQPQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            44788..45429
                     /gene="nadD"
                     /locus_tag="ROH59_001604"
     CDS             44788..45429
                     /gene="nadD"
                     /locus_tag="ROH59_001604"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDX4804103.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSMQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            45453..46064
                     /locus_tag="ROH59_001605"
     CDS             45453..46064
                     /locus_tag="ROH59_001605"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HDX4804104.1"
                     /translation="MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLHD
                     VSFDLVLCSELERAQHTARLVLSDRQHPVHIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQQAIPTNGEGFQAFSQRVERFIARLSEYQHYQNILVVSHQGVLSLLIARL
                     IGMPAESMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA"
     gene            46324..46641
                     /gene="rsfS"
                     /locus_tag="ROH59_001606"
                     /gene_synonym="rsfA"
     CDS             46324..46641
                     /gene="rsfS"
                     /locus_tag="ROH59_001606"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDX4804105.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            46645..47112
                     /gene="rlmH"
                     /locus_tag="ROH59_001607"
     CDS             46645..47112
                     /gene="rlmH"
                     /locus_tag="ROH59_001607"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDX4804106.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            47143..49044
                     /gene="mrdA"
                     /locus_tag="ROH59_001608"
     CDS             47143..49044
                     /gene="mrdA"
                     /locus_tag="ROH59_001608"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HDX4804107.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            49047..50159
                     /gene="mrdB"
                     /locus_tag="ROH59_001609"
                     /gene_synonym="rodA"
     CDS             49047..50159
                     /gene="mrdB"
                     /locus_tag="ROH59_001609"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HDX4804108.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            50170..51258
                     /gene="rlpA"
                     /locus_tag="ROH59_001610"
     CDS             50170..51258
                     /gene="rlpA"
                     /locus_tag="ROH59_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HDX4804109.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVPVPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAASQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            51398..52609
                     /gene="dacA"
                     /locus_tag="ROH59_001611"
     CDS             51398..52609
                     /gene="dacA"
                     /locus_tag="ROH59_001611"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HDX4804110.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            52719..52982
                     /locus_tag="ROH59_001612"
     CDS             52719..52982
                     /locus_tag="ROH59_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HDX4804111.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            53083..53724
                     /gene="lipB"
                     /locus_tag="ROH59_001613"
     CDS             53083..53724
                     /gene="lipB"
                     /locus_tag="ROH59_001613"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HDX4804112.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDESTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA"
     gene            53984..54508
                     /locus_tag="ROH59_001614"
                     /pseudo
     CDS             53984..54508
                     /locus_tag="ROH59_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415162.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
     gene            54749..55714
                     /gene="lipA"
                     /locus_tag="ROH59_001615"
     CDS             54749..55714
                     /gene="lipA"
                     /locus_tag="ROH59_001615"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HDX4804113.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(55814..56017)
                     /gene="tatE"
                     /locus_tag="ROH59_001616"
     CDS             complement(55814..56017)
                     /gene="tatE"
                     /locus_tag="ROH59_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HDX4804114.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(56146..56934)
                     /locus_tag="ROH59_001617"
     CDS             complement(56146..56934)
                     /locus_tag="ROH59_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
                     /protein_id="HDX4804115.1"
                     /translation="MLVAAGQFAVTSVWEKNVEICASLMAQAAENEVSLFVLPEALLA
                     RDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG
                     NIVARYAKLHLYDAFAIQESRHVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
                     LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPF
                     GVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL"
     gene            57027..57410
                     /gene="crcB"
                     /locus_tag="ROH59_001618"
     CDS             57027..57410
                     /gene="crcB"
                     /locus_tag="ROH59_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDX4804116.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIG
                     AFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(57464..57673)
                     /gene="cspE"
                     /locus_tag="ROH59_001619"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(57464..57673)
                     /gene="cspE"
                     /locus_tag="ROH59_001619"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDX4804117.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(57848..58408)
                     /gene="pagP"
                     /locus_tag="ROH59_001620"
     CDS             complement(57848..58408)
                     /gene="pagP"
                     /locus_tag="ROH59_001620"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HDX4804118.1"
                     /translation="MNVSKYVAIFFFVFIQLISVGKVFANADEWMTTFRENIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGQSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     ATFQMTYIPGTYNNGNVYFAWMRFQF"
BASE COUNT        14465 a        15150 c        14698 g        14284 t
ORIGIN      
        1 tttatttaat tatgttttgt gattttaaat ttattttatg gataaattgc gaagcggaat
       61 taattcgcga agaaaagcag aaaaaaacgc cgcagagcgc ggcgtttggg ataatttgca
      121 tatttcttgc cggatgcggc gtaaacgctc tatccgacaa cgtaaactta ctcgcctact
      181 ttcgcccagg tatcacgcag cccaacggtg cggttaaata ccggtttttc cgccgtagaa
      241 tggcggctgt cgaggcagaa gtaaccttca cgctcaaact ggaatgcttt acccgcaacc
      301 gcatctttca gcgacggttc agcaaagccc tgtttgatca ccagcgattc cgggttaatc
      361 accgacagga aatcatccgc agcaccaggg ttcggcacgc tgaacagacg gtcatacaaa
      421 cggatttcaa ccggcagcgc atgtgccgcg ctcacccagt gaataacacc tttgacttta
      481 cgaccatctg ccggatcttt gcttaaggtg tcggcgtcat aagtacagaa gatggtggtg
      541 atattgcctt cggcatcttt ctccacgcgt tctgccttaa tgacgtaagc attacgcaga
      601 cgcacttctt tacccagcac cagacgtttg tactgcttgt tagcttcttc gcggaaatcg
      661 gcgcgatcga tccaaatctc accgctaaat ggcacctgac ggctgcccat ttccggttta
      721 ttcggatggt tcggcatggt aaccatttcg ccttcgccct ggtagttttc gataaccagt
      781 ttcaccggat cgataaccgc cattgcgcgc ggcgcatttt cgttgagatc ttcacggatg
      841 caggattcca gtgacgccat ctcaatggtg ttgtcctgct tggtcacacc aatgcgtttg
      901 cagaactcac gaatagaagc cgcagtgtaa ccacgacgac gcagaccaga aatggtcggc
      961 atacgcgggt catcccagcc ttcaacgtgc ttgtcggtca ccagcaggtt cagcttacgc
     1021 ttggacatca cagtgtattc cagattcagg cgcgagaatt cgtactggcg cgggtgaaca
     1081 ggaatggtga tgttgtccag tacccagtcg tacagacgac ggttgtcctg gaactcaagc
     1141 gtacacagag agtgcgtaat accttccagc gcatcgctga tgcagtgggt gaagtcgtac
     1201 atcgggtaga tgcaccactt gttgccagtc tggtggtgtt cagcaaactt aatgcggtac
     1261 agcaccggat cgcgcatcac gataaacggc gaagccatgt cgattttcgc acgcaggcag
     1321 gctttacctt cttcaaaacc gccggtacgc attttctcga acagcgccag gttctcttca
     1381 acgctgcgat cgcggtacgg gctgttttta cccggctgcg tcaaggtgcc gcggtattcg
     1441 cggatctgtt ccggcgtcag ttcatcaacg tacgccaggc ctttattgat cagttcgatc
     1501 gcataggcgt ggagctgatc aaaataatcg gaggagtaac ggacgttacc agaccagtga
     1561 aaacctaacc actctacgtc gtttttgatc gaatcgacat actcgatatc ttcttttacc
     1621 gggttagtgt cgtcgaaacg caggttgcac tggcctttat agtcctgggc gatcccgaag
     1681 ttcaggcaga tagatttcgc atggccaata tgcagatagc cattcggctc cggcgggaaa
     1741 cgggtgtgta ctgtggtgtg cttaccactg gccagatctt catcgatgat ctgacggata
     1801 aagttagtcg ggcgggcttc tgcctcactc atcgtggatt cctcaaagcg taaacaacgt
     1861 ataacggcgt atgatcttat aagcgggaca ggctgacaac tgttagttag cgaaaaaatg
     1921 gttttgcgta agatattggg gcgttttctg cgctactgcc agcagatcct cgcgctggaa
     1981 acgtaaggcc aaacgtcgcc agcctgacgc atttattaaa tttccggatg agctggccgc
     2041 agagtcgtag attagtcggc tatgattaaa cgcgtcgaca aggacgcaag cgttctacgc
     2101 gtctgcccat caagctgact atccgtaata atctctgtca gttcattaag atgcgcgata
     2161 ttaaacagcg accatgaacc gtattttgag ctgtcagcca ggagaatttt gcgcgaagca
     2221 tgcgcgataa gatcgcgttt tagtgcggct ttctcttccg tgggtgctgt aatacccttt
     2281 tcaagatccc agctgttaca gcttaaaaat gccacgtccg gccaggtatt ttgcagcaat
     2341 ttacgaccat gttcgccaat gcaggactgg ctggagtcgt caatacgtcc gccgataatc
     2401 gtcacttcaa tttgcttgaa ttcagccaaa aaaagcgcga tatgcaggtc gcttgtgatc
     2461 acgcgaagcg gtaaatgtgt aatctgccgc gcaagttcaa tcattgtcgt accggcatca
     2521 aggacgacgg aatcccccgc tttgaccatt gacgccgctg cgctggcgat ggcatgtttt
     2581 tccgccaggc tgcgctgcat tttctcatgg gtagtcggtt gggtaggaat aaaccggttg
     2641 agagtcacac cgccgtgtgt acggctgata acaccctgct catcgagttt tatcaggtct
     2701 cgacgaatcg tagccggcga cgcattggtt accgccacca gctcatctac ggtgaccaga
     2761 ttatggcttt tcaggtaatc catgatctgc tctaaccggt tatatccctt cattttattc
     2821 tcgcgaaatc tgcattgcta actggatgga aactgccatg ctctcagact tggcttttcc
     2881 tgtccaggca atatcaaacg cggtgccgtg gtcggcagaa gtgcgaataa atggcaaccc
     2941 ggcggtgata ttcaccccat cataaaatcc aagcagtttt aaagggatat gcccctgatc
     3001 gtggtacata gccactacca tatcgaatag cccttcatgg cattgcataa acacggtatc
     3061 tggcgggcac gggccagtaa catcaatatc ttcggcctgc attgcttcaa tcgcaggcgc
     3121 gataatctcg atttcctcag tgccgaataa accatgttcc cctgcatgtg gatttacacc
     3181 cgccacggca atacgcggac gctcaatacc aacacgtttc aggaagtggt tcgcaactcg
     3241 aataaccgtt ttgacccttt caccattcaa agtatccagg aatttacgca gtgagatgtg
     3301 agtcgaaata tggataacct tgagcttctc ggtatagagc accatcgcgt actctttgct
     3361 gccggtaaga tgggccagca attccgtatg ccccggatag ttatgcccgc caagatgcag
     3421 cgcttcttta ttcagcggcg cagtggctat ggctttcacc tcgcctgata aggccagagc
     3481 cgttgcacgt ttgatacagc gatacgctaa atcgcctgcc acagcctgta ccactccggg
     3541 tgtcagcgca tcggggttag ccagcggctc atccatcacg ttaatcacgc cgggagcaaa
     3601 atgggcgtcg cacacctttt gaatgacgcg taactctgcc tgcggcgtga tattcatcgc
     3661 cataatacgt cgcagcgtgc gcacacagcc caccaccacc accggggcac cagcaagccc
     3721 ggcttcgctc agggatttaa taatgatctc cgggccaata cccgccggat cgcccatcgt
     3781 taccgcaata atattattca ctacgcttct cctcgataaa attcagaacc tgatgcaacg
     3841 tggtctcatc gccaaaccca ccggctttcg tcatcaccga acgggaccag acgccgccca
     3901 gaaagtgacc gtatggaacg cattgcgcca ccttccccgt aatacgaaat ccggtcgcgc
     3961 ctaacgcact ggctgttgcc attgcgacat caccaccaga gagataaagc gcatcgggca
     4021 ttgcgcaaag cagaacttgc cgggtaagtt cgccaagaaa ccggcaaatt ttttccccaa
     4081 gtgcagcgcg actcatctgc caacgctggc aaagggtgtc gatctgatgc cttgctacag
     4141 aatcgttaca ggtgtggaca atacagtggt cgcctttctg caaggcctgc acaatacgcg
     4201 cgtcatagtc actggcattg cctgccagaa tgtgttcaac atcgacgtat atctgtgtga
     4261 tacgtgggtg tgaatgaagt gtggcgatct gccgttgagc gatttcgctc attgaaccaa
     4321 taatggccag cacggtgggt ggcggcataa tcgcggagcg ccgggcaacg gcatcacaaa
     4381 taccagcgga gccgaccagc agcagcggtt gtttagcctg catcacagcg gcagcgatgc
     4441 gatccaggtc gctgtccgtc tgcgcatcta tcacgccaat ccacggttgc tcataagaca
     4501 aatggctgag ctgagaaacc gtaacgggct ggcatggaat ggccgtctgc aaccggatga
     4561 tgtccgcaat tcgggcgctc aataccgggg ttttcggatc gctagcaaac tcggtttccg
     4621 ttatccgcac accgtttacc caacactcac cggccactgt ggtccttccc gcctgaggaa
     4681 atgcgggggc aaccactgcg cccgttatac cgcatgcctt catcagggct tcaatttctg
     4741 cgccgatatt gcctcgcagc gtggaatcta tctttttaat cacgagcggc gggttattcg
     4801 ccagagggag atgactcatc agcgaggtta ttttcatcgc cgccagctta ggatccatcg
     4861 cccgactgtc gctgttaatc acccatacgc tggcatcacc gcgataaggc atttcaaagg
     4921 ccacatcaac tgtatgcccc acctgcgcca ggcttacccc cgcgtcgttg gctcccgtga
     4981 aatcatcggc aacgatgaga atgctcggct tagtgattcc cttttccatc atcactccag
     5041 gttgttttat gataacaatg attatattca atcatgattg attaaatgtg agcaagctca
     5101 agttattaat cactcgaata aattataaaa ttagaccatg ttacgtaggc tacggcattt
     5161 tgaatgattg aattcaatca ccagaagaga ggttatttgt ggtaattatc aatagcacga
     5221 tactgagcgg cgcaggcgct atcccttccc tgacgtcgct cttacccgac atcagaaaaa
     5281 tgctgctggt cactgaccgt aatattgcgc agctcgacgg tgtgcagcag attcgcgcct
     5341 tactggaaaa gcactgcccg caggttaacg ttatcgataa tgtgcccgca gagcccacgc
     5401 atcatgatgt gcgccagcta atggatgccc ttggcgatgc ctcttttgat gtggtggtcg
     5461 ggatcggcgg tggcagcgtg ttggatgtgg cgaagctgct atcggtgctt tgccatccac
     5521 aatcaccggg gctggatgcg ctgcttgcgg gtgaaaaacc gactcagcgg gtgcaatcat
     5581 ggttgattcc tacaaccgcc ggaaccggct cagaagccac gccgaatgcg attctggcaa
     5641 tccctgagca aagcacgaag gtgggtatta tttcccaggt gctgttacca gactatgtgg
     5701 cgcttttccc ggaactgacc accagtatgc ccgcgcatat tgcggcgtcc acgggcattg
     5761 atgctctttg ccacttactg gagtgtttta ccgcgaccgt ggcaaatccg gtcagcgata
     5821 acgcggcgct gactgggtta agtaaacttt tccggcacat tcaacccgcc gtgaacgatc
     5881 ctcaggatct gcgcgcaaaa ctggaaatgc tgtgggcgtc ttactatggc ggcgtagcga
     5941 taacccatgc gggcacgcat ctcgttcatg cgctctccta cccgttaggt ggcaaatatc
     6001 atctgccgca tggcgtcgcg aatgccatct tgctggcgcc gtgcatggcg tttgttcgcc
     6061 cctgggcggt cgagaaattt gcccaggtct gggattgcat tcccgatgcg gaaaccgccc
     6121 tgagcgcgga agaaaaatct catgccctgg tgacctggtt acaggcatta gtcaatcaac
     6181 tcaagctacc caacaatctc gcggatctcg gcgtaccgcc agaggatatt gcctctctga
     6241 gcgaggcggc actgaacgtg aagcgcctta tgaacaatgt gccgtgccag cttgatctac
     6301 aggacgtaca ggccatttac caaacactgt ttccgcaaca tcaatttaag gaataaatca
     6361 tgccgaaaac cattgaaggt gtattaaccg ctatcgtcac cccgtttacc gcgaccggca
     6421 gtctgaatat cccggcgtta aaagtgcagg tgaatcgtca actggaagcg ggtaacgcga
     6481 ttttttgcgg cggcaccaac ggcgagtttt ttgtgttgaa tgaacaggag aagctcagcg
     6541 ttacgcaaac ctgcgtggat gaagtggctg gtcgtgcgcc agtcgtggca cacattggcg
     6601 agatctctac gcgcgaaacg attcgtctgg gtcagcagat tgaaaaactt ggcgtagatg
     6661 ccgtgtcggt cattgcccct tacttcgtac cgctgaaaca ggaagagttg attgcgcatt
     6721 acagcgcaat tgccgacaca ctgagcattc cgatgtttct ctataacatc ccggcccgca
     6781 ctggcaatac gatccagcca gaaaccgcgc gtgctctggc gtcgcacccc aatatcattg
     6841 ggattaaaga cagcgacgga agcgacgaaa gcctgaaggg ttttctcgat gcggtgcgcg
     6901 acattgacgg ctttaatgtg ctcaacggcc cggattcgct gatccataaa gggtttgtcg
     6961 agggatgttc agcctgtatc tctgggctcg ccaacgtcgc gccgcgagaa atcaatgcca
     7021 tctggtctcg cttccatgcc ggtgatattg aagggtctta tgaagcacag gagagtgtaa
     7081 cgggcctgcg taccgatctt tataaagtag cattctcccc ggctgcggtg aaaaaagcgt
     7141 tgcagcttat ggggcatgat gttggtgata gccgctacgc ggttaatttc acgcctgaac
     7201 agatcagcga gattcaacaa attattcgtc attataacat taattaaatt aactctatta
     7261 tccagcccgc tataaagttt agataaagag aataaaggat taccccatgt ttttgtggtt
     7321 tatgcagcca gatatctggc tcactttaat taccctcacc tttctggaaa ttattcttgg
     7381 ggtggataat attatttttc tttcactggt ggtggcaaaa cttccgttat cacaacaaaa
     7441 tatggcgcgt aaactgggtt taagctgcgc gatgattatg cggatattat tgctgatatc
     7501 cattgcgtgg ctttcacata ttacccagcc gctttttacc gtgctgacgc tggagatttc
     7561 gttccgcacg ttgattctgc tcgggggcgg gctgttcctg atttataaag cgatacagga
     7621 gatacgcgaa gagctgtcgc ccgcgcagga agacgaacat ggcagcggat cgcggcaact
     7681 gtcgttgtgc ggtgccattg tacagataat gctgctcgat atcgtgttta gcctggattc
     7741 ggtgatcacc gccgtcggcc tttctcagca tatatttatc atgattgccg ccgtaatgat
     7801 tgccgtcggt gtcatgatgt ttgcggcgaa aacaattggt gatttcgtta acgccacgcc
     7861 gtcaataaaa atactggcgt taaccttttt attgtttgtc ggtgtattgc tggttgccga
     7921 tagtctcaac attcatattg ccaaagagta tctctacttc gcgatatttt tctcattaag
     7981 tgttgagaca ctcaatatta tccgtgaaag aaaaaataaa aaagtttcga cattgatcga
     8041 aacgcatgaa tcgcactcgc attaataaat ctattaccaa ctttaagatg gagtctaact
     8101 atgtctgtag cccttattcg tgacggcgtc atccgtccat ccgaaaacga ttcgcatgtg
     8161 cttaccgcca tgctgccctc gtcctgcccg caaaaccacg cggcgaatat tctgcctttg
     8221 ccggatggcg cgttaatgtg cgtctggttt gcgggaacgc aggaaggtat tgccgatatt
     8281 tctgtctggg gatcgcgatt gcccgctggc ggaatgcagt ggagcgatgc ggccaaactt
     8341 tcccacgatg acacgcgttc agagcaaaac ccggtgctgt ttctcgcgcc ggataacgtg
     8401 ctgtggctcc tatggaccgc acaaatatcc ggtaatcagg acaccgccat cgtccgctac
     8461 cgtaagtcag acgacctcgg acaaacctgg ggcgagattg ccaccctgct tgataaaccc
     8521 ggtacgttca ttcgacagcc aatcacggtg cttgataacg gcaactggct gctgcccgtc
     8581 ttttattgcc gtacccaacc cggcgaaaaa tgggtcggca atgatgatat cagcgcagtg
     8641 aaaatttccg ctgacggtgg tcactcctgg cgcgatgtcg aggtgccgca aagtctcggc
     8701 tgtgttcata tgaatatcac aatgttgcac gacggtacgt tggttgctct ctttcgcagc
     8761 cgttgggcag acaacatcta tatcagccat tcagtggaca acggcgagag ttggtcggtg
     8821 ccgcaagcaa ccgaattgcc caacaacaat tcgtctattc aggtaacgac gcttgccagc
     8881 ggcgaactgg cgctggtgta caacgcgatg agtgcggcag gcgcagtaga acgtcgcgcg
     8941 tcgctttatg acgaaatcga cgatggcgac gacagccgca aagaaccgac agccgtcgga
     9001 cgctccgctt tctggggtgc cccacgcgcg ccgatgacgg tagcgatttc tgccgatggt
     9061 gggaaaagct ggtcgtggcg gcgcaatctc gatgaaggcg acggctactg catgaccaac
     9121 aattccctgg aaaagctaaa tcgtgagttc tcctacccca gcatcaaaca aagcccggac
     9181 ggtacgctac atatcgctta cacctggtgg cgtcaggcca tcaagtacgt acgcatctcc
     9241 cccgagtggg ttaaggggca ggcatcatga ttatcggtaa tctcaaccat ttgtcgctgg
     9301 cggggcttcc tgcctgggtg agaaatattc tgctgcgccc ggagtgttcg ttatcggcgt
     9361 tatccaccag agaggacggt cgctggcaac ctgaaggatg tcggtggttc tgctcgctgg
     9421 gaacttcaga cacgcaaccc gccgaacttc gccatacgga gtatcaccat ctatgggccg
     9481 atatacaggt ggtgattact ggttgtgagg gcattaatgc gggaacgcgg cccatcgctc
     9541 gcgaaaacga tgaagaacgt aagcccgatc tgtttatcgc cccatcccct gaaaacagtg
     9601 tcgccatcac cctacacgcc ggtgatttcg ccgtctttat gcctgaggaa cctcaccagg
     9661 cactgtgcgc aattggcacg gctacttcaa tacgcaaagc ggtctttaaa gtaccgcgcg
     9721 acatgctgga agcctaaaag gagagaaaaa atgacaatgg aaatgatcct ggcattagga
     9781 atactggtcc tgatgatcgt gctgatcatg tcggacaaaa tgccttttgg cgcaccgcca
     9841 ctgcttgcgt gtttattgct ggttgtatcg ggactttcga ccgttcaaca ggcttttgcc
     9901 ggattcgtca atccaagcgt ggtgatgatt gcagggttta tggtggtcat ggcggcgcta
     9961 caaaaaaccc ggcttatcag caacgttaaa tctgcgatga taagcctggt caataaaggc
    10021 agttaccgca gctatgggct gttgttagtc attgttatgc tgggtgccag tcttgccggc
    10081 accggagcga ccggttatta cgtgctaatt ctgtcgctgg tatccaccat tccgtacagt
    10141 aaaaagctac caacatcgaa attaatgatg cccctgggat ttgccaccaa ccacccgctt
    10201 cttcctatca atctcgcgct tctctttggc gttacggcga ccgtactcga aaccgcgggg
    10261 tttcatcagg cgatttcgat ggggcgcttt gcgctggtga atctcatcat gtcagcggct
    10321 ttcctcgcat ggagtcttat tgcctaccgt tttcttccgg atcatcccat tgcggatgct
    10381 tccgaggatg cgctggcggc acgcgaggaa acgtttaacg cccttcctgc ctggaaagaa
    10441 tattgcacta ttgccgcatt cgctgtcagc gttatcggca tgatgctaat gaacattctg
    10501 ggaaatatcg ccttcgttat tccgggtctt gcgggtgcgt ttgttctgat gatcgatgta
    10561 ctggacttca aagaagttcg cgatcatatg ggggctccgg tcattttaat gatggcgggg
    10621 gtgatcggtg tagctgatgc actggcgggc accggcttta cggcgatggt tggcgatgcc
    10681 gttgcaggtg tgctcggttc tggcgtctca ccgtttgtat ttattgtcgc ctttgctttg
    10741 cttaccagta cctgcgccac cttcacgggt tcgaatatgg ggtcagtata tatttttgcc
    10801 cccatcgcca ttgccgcctg tactagcctt gggcttaacc cgaccgctgc cgcgattgcg
    10861 gtggtgattt ctggctggaa tggcggctat atgcctattg acggaatgcc agccatgatc
    10921 ctcggaatgg ggaaatacaa acttcccgaa ttctgggtgt tctctgtacc aatgtatctc
    10981 atccgcattc tggcgctttg tgcaggcgct gtttttatct tcccaatgta atctcagaca
    11041 aaaaaagcgg cagagaagat ccctgccgct ttttattgtt ggatgcgacg ctgccgcgtc
    11101 gcatcagaca taaagcagat tactttttga tttcatacag cggtgtttga cccgccacaa
    11161 catggccctg agctttaatg ataaggccgc tgaaatcatc gatattgctg caaaccaccg
    11221 ggctaatcat cgaacgggcg ttagcgttca ggtaatccag atccatttcc agaatcggtt
    11281 gccctgcgct tacctgcgcg ccctcttcca ccagacgttt aaagccttta ccttccagcg
    11341 ctacggtgtc gatacccata tggacgacga tctccgcgcc tttttcggtt tccagacaga
    11401 acgcgtggtt ggtgttgaag attttcacga ttgttcctgc ggctggtgat acgacgattt
    11461 tatctgtcgg tttcaccgcc acaccgtcac ccaccgcttt gctggcgaat gcttcgtcag
    11521 gaatctgatc cagtgccaca acatccccgg taatcggcga taccagctcc gcgatagata
    11581 ccgcgtttgg tacagcctgc ggttttgcta caggagcggc agttgccgga gttgcttcag
    11641 ctgacgcagc ggctaccgga ccacgggcaa cgactttctt catcgcatcg ccgatggatt
    11701 ctgctttcgc gccaacaatc acctgaatag tctgtttgtt cagttttact accccagaag
    11761 cacccagacg tttacacatc gcatcgttga cgcgagctga gtcaaccacg gtaaggcgca
    11821 gacgagtaat acaggcgtca atggctttca ggttgtcagt accgccaacc gcagcaatat
    11881 agttggttgc cagttgattg agaccttctt cagtattgct gttagcctct tcagtaacga
    11941 tctcgtcttc tttatcttca cgacccggcg ttttcaggtt gaacatgcgg ataaccaaac
    12001 tgaacaccac gaagtagata gcgaagaaga caacccccat caccagcagc atccagacgt
    12061 tctggctggc ggccggcagg ttatacatca acgcgtagtc gatagccccc gcagagaaag
    12121 agaagccggc atggataccc agcaacgttg ccacaaacag gctgataccg gtcagcagtg
    12181 cgtgcaggag gtacagcagc ggtgcaagga acatgaacag gaattccagc ggctcagtca
    12241 caccggtcag gaacgcagta acagcaacag aaagcagcat cccgccaacc atcggacgac
    12301 gctctttcgg tgctgcgaag tacatcgcca gcgccgcacc cggcaggccg aacatcataa
    12361 tcgggaagaa gccggacatg aacatccccg cggtgccgtc accggcatag aagcggttga
    12421 tatcaccgtg gaaaaccgtt cccgccgcgt tggtgaattc accaatctgg aaccaggcga
    12481 tggtgttcag cacctgatgc agaccggttg ggatcagcag acggttgatg aaaccaaaga
    12541 taccggaacc cagcgcgccc gcagaaacga tccactcgcc gcctgcatgg atagcgtgct
    12601 gtaccggtgg ccagacgtaa ccaaaaatgg ccgccagcac cagacagaag aagccggtgg
    12661 ctatcggcac aaagcgtttg ccgccgaaga agctcaggaa gtccggcagt ttaatatcgg
    12721 accaacggtt ataggctgcg ccaccaacca gaccggtaat gatacccgcc agtacaccca
    12781 tgttaatttc tgggttgatg gtcaccatcg ctttggttaa cacaaagtaa cctaccgcac
    12841 ccgccagtgc cgccgcacct gcgctgtctt tcgaccagct ggatgccacg ccgatggcga
    12901 atattaatgc gaggttatca aaaatcgcac cgcccgcctg ggcaataaac gcaacgttaa
    12961 gtaaatctgg ctgaccgaat cgcagcaaca gcgccgccac cggcagcacc gcgataggga
    13021 gctgtaacgc cctaccgagt cgctggaaaa aacctaaaat attcatctta ttccccctac
    13081 gagaacccta tttggctcgt ttaaagccgt atttttattt tgctgcaaat tgtactgccg
    13141 atgttctgta atcagattgt tagatcatct gctacagagt gtgtgaaaat ttaattcgta
    13201 tcgcaaatta aacgcgtgtc ttttgtgagt tttgtcacca aatatcgtta tcatcactcc
    13261 cttttactgg ctaaaccaga aaacttattt tatcattcaa aaaatcaggt cggattgacg
    13321 cctgtctgcg caaatccagg ttacgcttaa agatgcctaa tccgccaacg gcttacattt
    13381 tacttattga ggtgaataat gagactgatc cccctgacta ccgctgaaca ggtcggcaaa
    13441 tgggctgctc gccatatcgt caatcgtatc aatgcgttca aaccgactgc cgatcgtccg
    13501 tttgtactgg gcctgccgac tggcggcacg ccgatgacca cctataaagc gttagtcgaa
    13561 atgcataaag caggccaggt cagctttaag cacgttgtca ccttcaacat ggacgaatat
    13621 gtcggtctgc cgaaagagca tccggaaagc tactacagct ttatgcaccg taatttcttc
    13681 gatcacgttg atattccagc agaaaatatc aaccttctca acggcaacgc cccggatatc
    13741 gacgccgaat gccgccagta tgaagaaaaa atccgttctt acggaaaaat tcatctgttt
    13801 atgggcggtg taggtaacga cggtcatatt gcatttaacg aaccggcgtc ttctctggct
    13861 tctcgtactc gtatcaaaac cctgactcat gacactcgcg tcgcgaactc tcgtttcttt
    13921 gataacgatg ttaatcaggt gccaaaatat gccctgactg tcggtgttgg tacattgctg
    13981 gatgccgaag aagtgatgat tctggtgctg ggtagtcaga aagcactggc actgcaggcc
    14041 gccgttgaag gttgcgtgaa ccacatgtgg accatcagtt gtctgcaact gcatccaaaa
    14101 gcgatcatgg tgtgcgatga accttccacc atggagctga aagttaagac tttaagatat
    14161 ttcaatgaat tagaagcaga aaatatcaag ggtctgtaat tgttatccct gccctggctc
    14221 cttgctcagg gcaatatttt ttaaaatcgg gggtcagaat gtatgcatta acccagggcc
    14281 ggatctttac cggccacgaa tttcttgatg accacgcggt tgttatcgct gatggcctga
    14341 ttaaaagcgt ctgtccggta gcggaactgc cgccagagat cgaacaacgt tcactgaacg
    14401 gggccattct ctcccccggt tttatcgatg tgcagttaaa cggctgcggc ggcgtacagt
    14461 ttaacgacac cgctgaagcg gtcagcgtgg aaacgctgga aatcatgcag aaagccaatg
    14521 agaaatcagg ctgtactaac tatctgccga cgcttatcac caccagcgat gagctgatga
    14581 aacagggcgt gcgcgttatg cgcgagtacc tggcaaaaca tccgaaccag gcgttaggtc
    14641 tgcatctgga aggtccgtgg ctgaatctgg taaaaaaagg cacccataat ccgaattttg
    14701 tgcgtaagcc tgatgccgcg ctggtcgatt tcctgtgtga gaacgccgac gtgattacca
    14761 aagtgactct ggcaccggaa atggttccag cggaagtcat cagcaaactg gcaaatgccg
    14821 ggattgtggt ttctgctggt cactccaacg cgacgttgaa agaagcgaaa gccggtttcc
    14881 gcgcggggat tacctttgcc acccatctgt acaacgcgat gccgtatatt accggtcgtg
    14941 aaccgggcct ggcgggcgcg atcctcgacg aagctgacat ttattgcggt attatcgctg
    15001 atggcctgca tgttgattac gccaacattc gtaacgctaa acgtctgaaa ggcgacaaat
    15061 tgtgtctggt taccgatgcc accgcgccag caggtgccaa cattgaacag ttcatttttg
    15121 cgggtaaaac aatatactac cgtaacggac tttgtgtgga tgagaacggt acgttaagcg
    15181 gttcatcctt aaccatgatt gaaggcgtgc gtaatctggt cgaacattgt ggtatcgcac
    15241 tggatgaagt gctgcgtatg gcgacgctct atccggcacg tgcgattggc gttgagaaac
    15301 gtctcggcac gctcgccgca ggtaaagtag ccaacctgac tgcattcaca cctgatttta
    15361 aaatcaccag gaccatcgtt aacggtaacg aggtcgtaac tcaataagag aaagtatgac
    15421 accaggcgga caagctcaga taggtaatgt tgatctcgta aaacagctta acagcgcggc
    15481 ggtttatcgc ctgattgacc agtacgggcc aatctcgcgg attcagattg ccgagcaaag
    15541 tcagcttgcc cccgccagcg taaccaaaat tacgcgtcag cttatcgaac gcgggctgat
    15601 caaagaagtt gatcagcagg cctccaccgg gggccgccgc gctatctcca tcgtcaccga
    15661 aacccgcaat ttccacgcaa tcggcgtacg gcttggtcgt cacgacgcca ccatcacctt
    15721 gtttgatctc agcagcaaag tgctggcaga agaacattac ccgctgccgg aacgtaccca
    15781 gcagacgctg gaacatgccc tgctgaatgc cattgctcag tttattgata gctaccagcg
    15841 caagctacgc gagctgatcg cgatttcggt gatcctgcca gggcttgtag acccggacag
    15901 cggcaaaatt cattacatgc cgcatattca ggtagaaaac tgggggctgg ttgaagcact
    15961 ggaagagcgt tttaaagtga cctgttttgt cggccacgat atccgcagtc tggcgctggc
    16021 agagcactac ttcggtgcaa gtcaggattg cgaagactcc attctggtgc gtgtccatcg
    16081 cggaaccggg gccgggatta tctctaacgg gcgaattttt atcgggcgca acggcaacgt
    16141 cggtgaaatt ggccatattc aggtcgaacc gctgggtgaa cgctgccact gcggcaactt
    16201 tggctgcctg gaaactatcg ccgccaatgc tgccattgaa caacgggtgt tgaatctgtt
    16261 aaagcagggc taccagagcc gtgtgccact ggacgactgc accatcaaaa ctatctgcaa
    16321 agccgcgaac aaaggcgata gcctggcctc ggaagtgatt gaatatgtcg gtcgtcatct
    16381 gggtaaaacc atcgccattg ctatcaactt atttaatccg caaaaaattg ttattgctgg
    16441 agaaatcacc gaagccgata aagtgctgct ccctgctatt gaaagctgca ttaataccca
    16501 ggcgctgaag gcgtttcgta ctaatctacc ggtggtacgt tctgagttgg atcaccgctc
    16561 ggcaatcggc gcttttgcgc tggtaaaacg cgccatgctc aacggtattt tgctccagca
    16621 tttgctggaa aattaatgtg cttttatagt ggcgcttatt gttgtcaata ttctgggtag
    16681 tccatgacca ttaaaaatgt aatttgcgat atcgacggcg tgctgatgca cgataacgtc
    16741 gccgtaccgg gtgcagcgga atttttgcac gggattatgg ataaaggcct gccgctggtg
    16801 ttgctgacca actatccttc gcagaccggg caagatctgg cgaatcgctt tgccactgcc
    16861 ggtgtcgatg taccggatag cgtgttttat acctccgcaa tggcgaccgc cgattttctg
    16921 cgtcgccagg aaggcaagaa agcgtatgtg gtgggcgaag gcgcactgat tcatgaactg
    16981 tacaaagccg gtttcactat taccgatgtg aaccctgatt ttgtgattgt tggcgaaacg
    17041 cgttcctaca actgggacat gatgcataaa gcagcctatt tcgtcgctaa cggtgcacgc
    17101 tttatcgcca ccaacccgga cacccacggg cgcggttttt atcccgcctg tggcgcgttg
    17161 tgtgcaggga tcgagaaaat ctccgggcgc aaaccgttct atgttggaaa gccgagtccg
    17221 tggatcatcc gcgcggcatt aaacaaaatg caggcgcatt cggaagaaac ggtgattgtc
    17281 ggcgataact tgcgtaccga tattctggcg ggcttccagg ccggtctgga gacgattctg
    17341 gtgctttctg gtgtttcgtc gctcgacgat atcgacagta tgccgttccg cccaagttgg
    17401 atttacccat cggtcgctga aatcgacgtt atctgaatag caaccacgcc tcagggcgtg
    17461 gtttcttatt tttacccatc attaaaatca ccccattcaa taaaacccgt caaaaactat
    17521 cgatccatca ataaatatac ccaaaagccc tccccttttt catcaatcag caatcgccat
    17581 tacgtttttt atttttccac tgccaaatcg cttgcgcacc gtgctgcttt gcggcatttt
    17641 tttaacaagt aaacacaaca cgcagtaaac accaggttaa tggagaaggt tatgtgttca
    17701 atttttggcg tattcgatat caaaacagac gcagttgagc tgcgtaagaa agcactcgag
    17761 ctgtcacgcc tgatgcgtca tcgtggcccg gactggtccg gtatttatgc cagcgataac
    17821 gccattctcg cccacgaacg tctgtcaatt gttgacgtta acgcgggggc gcaacctctc
    17881 tacaaccaac aaaaaactca tgtgctggca gtaaacggtg aaatctacaa ccaccaggca
    17941 ttgcgcgctg aatatggcga tcgttaccag ttccagaccg ggtctgactg tgaagtgatc
    18001 ctcgcgctgt atcaggaaaa agggccggaa tttctcgacg acttgcaggg catgtttgcc
    18061 tttgccctgt acgacagcga aaaagatgca tatctgattg gtcgcgacca tctggggatc
    18121 atcccactgt atatgggcta tgacgaacac ggtcagctgt atgtggcctc agaaatgaaa
    18181 gccctcgtgc cagtttgccg cacgattaaa gagtttccgg cggggagcta tttgtggagt
    18241 caggacggcg aaatccgttc ttattatcat cgcgactggt tcgactacga tgcggtgaaa
    18301 gataacgtga ccgacaaaaa cgagctgcgt caggcactgg aagattccgt taaaagccat
    18361 ctgatgtctg atgtgcctta cggtgtgctg ctttctggtg gtctggattc ctcaattatt
    18421 tccgctatca ccaagaaata cgccgcccgt cgcgtggaag atcaggaacg ctctgaagcc
    18481 tggtggccgc agttgcactc ctttgctgta ggtctgccgg gttcaccgga tctgaaagca
    18541 gcccaggaag tggcaaacca tctgggcacg gtgcatcacg aaattcactt cactgtacag
    18601 gaaggtctgg atgccatccg cgacgtgatt taccacatcg aaacttatga tgtgaccact
    18661 attcgcgctt caacaccgat gtatttaatg tcgcgtaaga tcaaggcgat gggcattaaa
    18721 atggtgctgt ccggtgaagg ttctgacgaa gtgtttggcg gttatctcta cttccacaaa
    18781 gcgccgaacg ctaaagagtt gcatgaagag acggtgcgta aactgctggc cctgcatatg
    18841 tatgactgcg cgcgtgccaa caaagcgatg tcagcctggg gcgtggaagc acgcgttccg
    18901 ttcctcgaca aaaaattcct tgatgtggcg atgcgcatta acccacagga taaaatgtgc
    18961 ggtaacggca aaatggaaaa acacatcctg cgtgaatgtt ttgaagcgta tctgcctgca
    19021 agcgtggcct ggcggcaaaa agagcagttc tccgatggcg tcggttacag ttggatcgac
    19081 accctgaaag aagtggcagc gcagcaggtt tctgatcaac agctggaaac tgcccgcttc
    19141 cgcttcccgt acaacacgcc gacctcaaaa gaagcgtatc tgtaccggga gatctttgaa
    19201 gaattgttcc cgcttccgag cgccgctgag tgcgtgccgg gcggtccttc cgtcgcttgt
    19261 tcttccgcta aagcgattga gtgggatgaa gcgttcaaga aaatggacga tccgtctggt
    19321 cgcgcggttg gcgttcacca gtcggcatat aaataagacg tgtaatattg ccccggagaa
    19381 atccggggca atttcagtta ctggggcgct tgttgattct gatatgcagt aaggaaatgt
    19441 tccgggtttg ccacatcgct atttgacaac tcatcactgt aggccaccaa ccaggtcgcc
    19501 tgctcatccg gaatatgcag tctgccattt ccctctttca ggcgtaataa ctcaaaagat
    19561 ttgcccttaa ttacggcggt ataggatttc tcaccttcct gtaatgcttt cactttacag
    19621 cgaaatatct gaccatcgat gtcattatca acatgcgata cctgaatgag ggcttcatta
    19681 gaagctttcg ggcctatccg catcatccac accacagcgc cttcctgccc acgatagcca
    19741 aaaacatatt taccgatttc cggtttaacc gtatcggcga acgcagattg cataagtaat
    19801 aacgcaccca tcaacgccgt cataaaacgc agcatagtat tccctcaata aatcgcctga
    19861 agtggtagca gagatgcagg cgtagcgatc cctgccctgt cctgttgcaa cgggccagta
    19921 tttcatagat taatttccca ccactattgt tgaattccga atttcatcct gtatgacaaa
    19981 agaatggctg tagggtgggg aaaaaacaca aagtaaacaa taattgacga atatagcgcc
    20041 atgctgttcg caacctaacc aaacagtcac tttcgagcaa ttttccttga aaaagaggtt
    20101 gacgctgcaa ggctctatac gcataatgcg ccccgcaacg ccgataaggt atcgcgaaaa
    20161 aaaaagatgg ctacgtagct cagttggtta gagcacatca ctcataatga tggggtcaca
    20221 ggttcgaatc ccgtcgtagc caccatcttt tttttgcggg agtggcgaaa ttggtagacg
    20281 caccagattt aggttctggc gccgcaaggt gtgcgagttc aagtctcgcc tcccgcacca
    20341 ttcaccagaa agcgttgtac ggatggggta tcgccaagcg gtaaggcacc ggtttttgat
    20401 accggcattc cctggttcga atccaggtac cccagccata ttcttcgagt aagcggttca
    20461 ccgcccggtt attggggtat cgccaagcgg taaggcaccg gtttttgata ccggcattcc
    20521 ctggttcgaa tccaggtacc ccagccatcg aagaaacaat ctggctacgt agctcagttg
    20581 gttagagcac atcactcata atgatggggt cacaggttcg aatcccgtcg tagccaccaa
    20641 attctgaatg tgtcgaatat gttcggcaaa ttcaaaaacc aatttgttgg ggtatcgcca
    20701 agcggtaagg caccggattc tgattccggc attccgaggt tcgaatcctc gtaccccagc
    20761 caatttattc aagacgctta ccttgtaagt gcacccagtt ggggtatcgc caagcggtaa
    20821 ggcaccggat tctgattccg gcattccgag gttcgaatcc tcgtacccca gccacattaa
    20881 aaaagctcgc ttcggcgagc tttttgcttt tctgcgtata ttcaatgccg aatacgatgt
    20941 tgactcgtct tatccttaca aagtcggatg cgacgctgcc gcgtcttatc cgacctacgg
    21001 ttggcatgca tccagcaatg ttgtgaggct acaaccctaa cgcatatttc agcgccttac
    21061 gtttcaacac gccagcacgc tccgccgcca tcaaaccaag attacgcaca aaacgcagcg
    21121 gtggcagatt attgctgaat ccggcataaa acagatccat accactttgc atcatgaagt
    21181 tatccgccat acgccgcatc tggtaacgct tgagcacagg ataactggcc cacgcttcgc
    21241 cgtagctgcg ggcgttcacc agaacgtcaa tcagggcatc gacatcacga taaccaagat
    21301 tcactccctg ccccgccagc ggatggatgg tatgcgcggc atcgcccacc agagcaagcc
    21361 ctggttgcac atactgcaac gcatggcgac gtataagcgg aaacgcacca gcggcaagcg
    21421 gtgtcacgta acccagacgc gacgggaaat gcttcgcgat ttccgcctgt agctgcgcca
    21481 tattcatatt ctgcaactgg cgaatgcgcg ccggagagtc ataccacacc agcgatgccc
    21541 agttatcaaa caacggcaga aacgcacgcg gtccgtccgg ggtaaattgc tgccaggtgc
    21601 tgtcgccggg atcgttctca cactgtacgc taatcaacat acacgactgc gcatactgcc
    21661 aggcatgaac gccaattccc gccatctgtc gcacctgcga atttgcgccg tcggcaccaa
    21721 tcaccagctt cgcgaggatc gtttcaccgc ccttcagttc cagctcctga agatcattat
    21781 ggcgatgcag tgcagtcagc gaggttggca cacgtaacgt tactttcgga tgcgcttcca
    21841 gcgcctgcca caaagcctgt tgcaggacag tgttttccac catgtagcca agcaacggta
    21901 gcttaagttc agcggcgtca aacacgacat gcgccgtttc ccactcccac gtttccagtc
    21961 tgcggtaagg atggcaacgc atagcctgta ctgcatccca gacccctaac cctttaagca
    22021 atgataccga agccgcgctg atcgccgaga tccgcacatc cggttggctg tcagcgacaa
    22081 acggcgcagg ttctgcgtgc tcgatcaccg ttaccgtaaa cccgtgctgt gccagcccca
    22141 gcgccagtgc gccgccgacc attcctccgc cgacaatggc aatttccgtt ggttgatttg
    22201 tcatggtcaa tcatcctgtt agcaatatgc tttaagttta caggattttt acccccaagg
    22261 gctgataacg ctcatactgg tcacaacggc agcaaagcat tacactatgc gccctgcatt
    22321 cctggctact atttcgcaag agcaagtcga tgaccaaaaa actccatatt aaaacctggg
    22381 gctgtcagat gaacgagtac gattcatcga agatggccga tctgctggat gccacccacg
    22441 gctatcaact gaccgacgtg gcggaagaag cggatgtgct gctgctgaac acctgctcaa
    22501 tccgcgagaa ggctcaggaa aaagtcttcc atcagttggg tcgctggaaa ctgttaaaag
    22561 agaagaatcc agacctgatt atcggcgtcg gcggctgcgt ggcatcgcaa gaaggcgagc
    22621 acattcgcca gcgcgcccac tatgtcgata ttatttttgg gccgcaaacg ctgcatcgtc
    22681 taccggagat gatcaactcc gtgcgcggcg accgcagccc ggttgtagat atcagcttcc
    22741 cggaaatcga gaagtttgac cgtctgccgg aaccgcgcgc cgaagggccg accgcgtttg
    22801 tctccatcat ggaaggctgc aataaatatt gcacctactg cgtggtgcct tacacccgtg
    22861 gtgaagaggt aagccgtccg tccgacgata ttctgtttga gatcgcccag cttgcggctc
    22921 agggcgtgcg tgaagtcaac ctgctcggtc agaatgtgaa tgcctggcgt ggtgagaact
    22981 acgacggcac caccggaacg tttgccgatc tgctgcgtct ggttgcggcg attgacggga
    23041 tcgatcgtat tcgctttacc accagccatc cgatcgaatt caccgacgat atcatcgaag
    23101 tgtatcgcga cacgccggag ctggtgagct tcctgcactt gccggtacag agcggttccg
    23161 atcgcattct gaacctgatg ggccgtactc acacggcgct ggagtacaaa gcgatcatcc
    23221 gtaaactgcg tgcggcgcgt ccggatattc agatcagttc tgacttcatc gttggcttcc
    23281 ctggcgaaac caccgacgac ttcgagaaaa cgatgaagct gattgccgac gtcaatttcg
    23341 acatgagcta cagctttatc ttctccgctc gtccaggaac gcctgccgcc gatatggttg
    23401 atgatgttcc ggaagaagag aagaagcagc gtctgtatat tctgcaagag cgcattaatc
    23461 agcaagcgat ggcatggagc cgccgtatgc tcggcaccac ccagcgtatt ctggtagaag
    23521 gtacatcgcg taagagcatc atggagcttt ccggtcgtac tgaaaataac cgcgtggtta
    23581 acttcgaagg cacgccggat atgatcggta aattcgtcga tgtagaaatt accgacgtct
    23641 atccaaactc cctgcgcgga aaagtggtgc gtactgaaga tgaaatgggt ctgcgcgtcg
    23701 cagaaacacc ggaatcggtg attgcccgta cccgcaaaga aaacgacctt ggcgtgggtt
    23761 attatcagcc gtaattctca ggcccgccgt tccggtgggc cttgtttttt ctctctttat
    23821 ccccatcttt atcgcaatgc ttgcgccttt ttcctgtggc gtgaataatt tccttatagg
    23881 ccggtgaatg ttcagcttcc ggcggcatac agataagagg aacggtttga acatagacac
    23941 tcgcgaaatc accctggagc cagcagacaa tgcgcgtctg ttgagcctgt gcggcccgtt
    24001 tgatgacaac atcaaacaac tcgaacgccg tctcggcatc gaaatcaatc gccgtgataa
    24061 ccactttaaa ctgaccggcc gtccgatttg cgtcaccgct gcggcagaca ttctgcgtag
    24121 cctgtatgtc gatactgccc cgatgcgcgg tcagattcag gatatcgaac cggaacagat
    24181 ccaccttgcg attaaagaag cgcgggtact ggagcaaagc gcggagagcg tgccggagta
    24241 cggcaaagca gtcaatatca aaaccaaacg cggcgtaatt aagccgcgca cgccaaacca
    24301 ggcgcagtac atcgccaata ttctcgacca tgacattacc ttcggcgttg gcccggcggg
    24361 tacgggtaaa acctacctgg cagtggctgc ggcagttgat gccctggagc gtcaggaaat
    24421 tcgccgtatt ctgctgactc gtccggcggt cgaagccggt gagaaactgg gcttcctgcc
    24481 tggcgattta agccagaaag tagacccgta tctgcgcccg ctgtacgacg cgctgtttga
    24541 aatgctgggc tttgagaaag tcgagaaact gattgagcgc aacgttattg aagtcgcacc
    24601 gctggcctat atgcgtggtc gtacgctgaa cgacgcgttt atcattcttg atgagagcca
    24661 gaacaccacc atcgaacaga tgaagatgtt cctgacccgt atcggtttta actcaaaagc
    24721 ggttatcacc ggcgacgtca cacagatcga cctgccgcgt aataccaagt ctggtttgcg
    24781 tcatgccatc gaagtgctgg ctgatgtcga agagatcagc tttaacttct tccacagcga
    24841 agacgtggtt cgtcacccgg tggtggcgcg tatcgttaac gcttatgaag cctgggaaga
    24901 agccgaacaa aaacgtaaag cggcgctggc ggcagaacgc aagcgcgaag aacaggaaca
    24961 aaaatgagtc aggtgatcct cgatttacaa ctggcatgtg aagataattc cgggttaccg
    25021 gaagagagcc agtttcagac atggctgaat gcggtgatcc cgcagtttca ggaagaatcg
    25081 gaagtgacta ttcgcgtggt cgataccgcc gaaagccaca gtctgaatct gacctatcgc
    25141 ggtaaggata agccgaccaa cgtgctctcc ttcccgtttg aagtgccgcc tggcatggaa
    25201 atgtcgctac tgggcgatct ggttatctgc cgtcaggtgg ttgagaagga agctcaggag
    25261 caaggcaaac cactggaggc gcactgggcg catatggtgg tgcacggcag tctgcatttg
    25321 ttaggttacg atcacatcga agatgacgaa gcagaagaaa tggaagccat cgaaacagag
    25381 attatgcttg ctctgggcta tgaggatccg tacattgccg agaaagaata atttgccagg
    25441 catttgactg gcagacgtcc ccgccgttgg tgattaacga cggcgttttg attaactaac
    25501 atgagaaccc atacgacgcc atgagcgacg acaattcaca cagtagtgac acgataagca
    25561 acaagaaggg atttttctcc ctgttactca gccaactttt ccacggtgaa ccgaaaaacc
    25621 gtgacgaact gctggcgctg atccgtgatt ccgggcagaa cgaccttatc gacgaagata
    25681 cgcgcgatat gctcgaaggg gtgatggaca tcgcagacca acgcgttcgc gacatcatga
    25741 tcccccgctc ccagatgatt accctgaaac gcaaccagac gctggacgaa tgccttgatg
    25801 tcatcatcga gtccgcccac tcacgtttcc cggtgattag cgaagacaaa gatcacattg
    25861 aagggattct gatggcgaaa gacttgctgc cgtttatgcg cagcgatgct gaagccttca
    25921 gcatggacaa agtgttacgt caggcggttg tcgttcctga aagtaagcgc gtagaccgga
    25981 tgctgaaaga gtttcgctct cagcgttacc acatggcgat cgtcattgac gaattcggtg
    26041 gggtttccgg tctcgtgacc attgaagaca tcctggaact gattgttggt gagattgaag
    26101 acgagtatga cgaagaagat gatatcgact tccgtcagct gagtcgtcat acctggaccg
    26161 tgcgcgcact ggcttctatt gaagacttca acgaagcgtt cggcacccac tttagcgatg
    26221 aagaggttga cactatcggt ggtctggtga tgcaggcatt tgggcatctt ccggcgcgtg
    26281 gcgaaaccat cgacatcgac ggttaccagt tcaaagtggc gatggccgac agtcggcgta
    26341 ttattcaggt tcatgtcaaa atcccggatg actcacccca gccgaagctg gatgaataaa
    26401 accgaaactg gatagataac tacatggctt ttgcctcatt aattgaacgc cagcgcattc
    26461 gcctgctgct ggcgttatta ttcggtgcct gcggaacgct ggccttctct ccttacgacg
    26521 tctggcctgc ggcgattatt tcgctgatgg gacttcaggc gctgaccttt aaccgccgtc
    26581 cactccagtc taccgctatt ggcttttgct ggggatttgg cctctttggc agcggtatta
    26641 actgggtcta tgtcagcatc gcgacctttg gcggaatgcc tggcccggtt aacatcttcc
    26701 tggtggtact gctggcggcg tatttgtcgc tgtataccgg actgtttgct ggcgtgctgt
    26761 cgcgtctgtg gccgaaaacc acctggctgc gcgtggcgat tgccgcccct gctctctggc
    26821 aagtgaccga gtttctgcgc ggttgggtac taacaggctt cccgtggtta cagttcggct
    26881 atagccagat tgatggcccg ttaaaagggc tggcaccgat aatgggcgtg gaagccatta
    26941 acttcctgct gatgatggtt agtggcctgc tggcactggc gttggtcaaa cgcaactggc
    27001 gtccgctggt ggtggccgtc gtgctgtttg cccttccctt cccgctgcgt tacgtccagt
    27061 ggtttacccc gcaaccggag aaaaccattc aggtttcgat ggttcagggc aatattccgc
    27121 aatcgctgaa atgggacgaa ggccagcttc ttaatacgct gaagatttac tacaacgcaa
    27181 cggcaccgct gatgggcaaa tcatcgctga ttatctggcc ggagtcggcg ataaccgatc
    27241 tggaaattaa tcagcaaccg ttcctcaaag ctctggacgg tgagttgcgc gataaaggta
    27301 gctcgctgat caccgggatt gtcgacgcgc gtctcaataa acagaaccgc tacgatacct
    27361 acaacaccat catcacactg ggtaaaggcg caccgtacag ctatgaatca gccgatcgct
    27421 ataacaaaaa ccatctggtg ccgtttggcg agtttgtccc actggagtcg attctgcgtc
    27481 cattagcacc gttctttgat ttgccgatgt cgtcattcag ccgcggacca tatattcagc
    27541 caccgctgtc gttgaatggc attcaactta ctgcggccat ttgctacgaa atcattctcg
    27601 gcgagcaagt gcgcgataac ttccgcccgg ataccgacta tctgctgact atctccaacg
    27661 atgcgtggtt tggtaagtct attggtccat ggcagcactt ccagatggcg cgaatgcgtg
    27721 cgctggagct ggcgcgccca ctgttgcgca gcaccaacaa cggcattacg gcggtgattg
    27781 gcccgcaggg tgagattcag gcgatgatcc cgcagttcac ccgcgaggtg ttaaccacta
    27841 acgtaacgcc gaccaccgga ctcaccccgt actcacgtac cggcaactgg ccactgtggg
    27901 tgctgacggc actgtttggc tttgccgctg tactgatgag tctgcgtgct cgcaaacgtt
    27961 aatgtgcctg atgcgcgacg cttatcaggc ctacgcgatt tttgcaatat gttgaatttt
    28021 cgcgattttg taggataaag cgtacttttt caacacgctc tggggcatga ttatcatgcc
    28081 cttttttctt acggttcagg gatacaagcc acatcgccat attggggatg ccgaataatt
    28141 gcctgcggat caagtgaact ttctctgtcc agttgtatta gcccgttctt cgccataaca
    28201 aatatctttc taccatccgc tgaaaaacga agatgattca cgtagctggc aggataaacg
    28261 ccaataatct gcccggcatt aatattgagc aggatgacat aaccttgcag gccatatgac
    28321 accaacgcta aatattgacc gtccgggcta ataccctcaa cggaataaac gctcctgcta
    28381 caccattgcg tcataatgct ggcttgttga tcctcagctc ttatacgtga aatcccctgg
    28441 ctatcggcaa aaataatctc accatttttt ggtcggaatc ccatcgcaga aacgacacca
    28501 cgcgcatcac ctgcgggaaa gtcttctttc tgatgcgtga tggtattgat ccgcacgatg
    28561 ttacctctgc ctgctcccgg aaccagtaat gttttttcat ccggggaaag tgccataacc
    28621 caggcgcctg gtttaccgct catccccgtc ccgtcgtatt tctccagcgg gatatccgcc
    28681 acatgctgat aagccaccag atcaatcgct gacacactat tactggtgcg attcatcacc
    28741 caggcttttg tgccatcacg cgagaggata aggctgtcag gatgtgcgcc ggtggtaatc
    28801 gactgaataa tctcccccgt tgccacgtta atgaccgata atgcattcgc ttcaaatgaa
    28861 gtcgcataca gcaacgtttc atccgggctt agcgccagcg acctgacgcc ctgatcttta
    28921 cagccaccac aatgtttgac tgacttttct ttcgctatgg gggctgtaaa ggtatgcagg
    28981 attttctttt gtccgaggtc gaaaacaaca atgctgttcg tgttttcaat tgcggcatac
    29041 aacgtattag catcccgact gatcgccata tcatggatat cggcaatctc agcgagtaaa
    29101 tcaccactgg cctgctcacg acttaccgga gcggataatg tttccctgag ggcgttgcgc
    29161 tcctccacta actgctgctt tttttgtcgt cgctcttgtt caatctcctg cggataaaac
    29221 gcttcacgca ggctttgcct gacctgtaaa actgattcat caatctgctg ctgcacaagc
    29281 cagatagtcc cggtcagaag aagagtgacc gcaacaataa tcccgccttc cgtaacgagc
    29341 cgattttgcc caactaaacg cgcactcagc caacccaacg cgccccccgc aatcaggccg
    29401 ccaatgtggc aagcgttatc tattcctgtt tgccgggtac catacaacag tgtcagcgcc
    29461 accataccca acagaggaaa tactcgccgc tggtttttat ggtgtgtgcc cgcacctgaa
    29521 gcaagctgtg ttgctatcgc agcgcccgct attcccataa ttgccccgga tgccccaacg
    29581 ctgatgacta tctgctcact ttcgcgtaac gcataacagg cgctgatcag cccaccaaag
    29641 atgccggaga ataaccagat aatcaggagt cgccatttcc ccagtatccg ttccgccact
    29701 gtccccacca ccaggagtgc aaacatattc atcagcaaat gggaaaaact actgtgcaga
    29761 aaaacactgc tcaataagcg ccaggattca tccgacaacg tgagagaagc aacgttagcg
    29821 ccgagatgga tgagtgcgga ttgatcgact tcttcgtaac tcatccattg tgcgaggtaa
    29881 caaaatatcc caacacagag cgcaaaaagg atcagggtta ttgcgggtaa ttgaacattt
    29941 aacggcttaa ccgaagatgc agacataagg tgattcttcc ttgaaaagac tagtaaaaag
    30001 cattttcccg tgtgtagtta tcatcccggc aaacgtccca caccgaaaag ttaacactgt
    30061 ccgaaatatg actttttcaa actgaaatta caatcgtaat taattcaccc ctaagtattt
    30121 tttggcatgt aagttgcttt atttactgtg taagcaatga aatcagccgc aacgcaaccg
    30181 ggttgcacca ccacaaatca gcggtagcac caaaaaggtg cggtttaaga attttgcttc
    30241 ggaatggtgc ggcgcacctc gcaaaaacaa acaataaaac agcaatatct ttacatttat
    30301 ccaaactaaa tgttacctaa caagcacaac actgcacaat aaagtcgcag atgataacaa
    30361 cacaaacact cacaacgggt atccatgcgt ttttaacgca gaagataaag gagttggata
    30421 tgcaattacg taaacctgcc acagcaatcc tggccctggc gctttccgca ggactggcac
    30481 aggcagatga cgccgccccg gcagctggca atacgctgga caaaatcgcc aaaaacggcg
    30541 tgattgtcgt cggtcaccgt gaatcttcag tacctttctc ttattacgac aatcagcaaa
    30601 aagtggtggg ctactcgcag gattactcca acgccattgt tgaagcagtg aaaaagaaac
    30661 tcaacaaacc agacttacag gtgaaattga ttccgatcac ctcacaaaac cgtattccac
    30721 tgctgcaaaa cggcactttc gattttgaat gcggttctac caccaacaat gccgaacgcc
    30781 aaaaacaggc ggctttctct aacactattt tcgtggtcgg tacgcgcctg ctgaccaaaa
    30841 agggcggtga tatcaaagat tttgccgacc tgaaaggcaa agccgtagtc gtcacttccg
    30901 gcaccacctc tgaagttttg ctcaacaaac tgaatgaaga gcaaaaaatg aatatgcgca
    30961 tcatcagcgc caaagatcac ggtgactctt tccgtaccct ggaaagcggt cgtgccgttg
    31021 cctttatgat ggatgatgct ctgctggccg gtgaacgtgc gaaagcgaag aaaccagaca
    31081 actgggaaat cgtcggcaag ccgcagtctc aggaagccta tggttgcatg ttgcgtaaag
    31141 acgatccgca gttcaaaaag ctgatggatg ataccatcgc tcaggtgcag acctccggtg
    31201 aagcggaaaa atggtttgat aagtggttca aaaatccaat tccgccgaaa aacctgaaca
    31261 tgaatttcga actgtcagac gaaatgaaag cactgttcaa agaaccgaat gacaaggcac
    31321 tgaactaatt acaagaacca ggggcggaaa ttccagccct ctcgattgtt acgtagcacg
    31381 gacagactat acgcctggtg gtcgttcccc atcgggcctg aaaaccgcaa tacgctgggt
    31441 aacaatcttc gagggtagca gttaacgctg ctaccctctt ttttctggag tagatttatg
    31501 tctatagact ggaactgggg tattttttta caacaagccc cgttcggcaa caccacctat
    31561 cttggttgga tctggagtgg ctttcaggtg acgatcgctt tgtcgatctg cgcctggatt
    31621 atcgctttcc tcgtcggttc atttttcggc attttacgta ccgttccaaa ccgttttctc
    31681 tccggtctgg gtacgttgta tgtcgaactg ttccgcaacg tgccgttgat tgtgcaattc
    31741 tttacctggt acctagtgat cccggagctg ctgccagaga aaatcggcat gtggtttaag
    31801 gcagagctgg atcccaatat tcagtttttc ctttcatcca tgctctgcct ggggctgttt
    31861 accgccgccc gtgtttgcga acaggtacgc gcagctattc agtcgctgcc gcgtgggcaa
    31921 aaaaatgccg cgctggcgat gggtctgacg ctaccgcagg cttaccgcta cgtactgctg
    31981 cctaatgctt atcgcgttat cgtcccgccg atgacctcag agatgatgaa cctggtgaaa
    32041 aactccgcca tcgcctcgac tatcggtctg gtggatatgg cggcgcaggc gggtaaattg
    32101 ctcgattact cggcccacgc ctgggagtcg tttaccgcca tcacgctggc gtatgtattg
    32161 attaacgctt ttatcatgct ggtgatgacg ctggttgaac gtaaagttcg cctgcccggc
    32221 aacatggggg gcaaataatg tacgagtttg actggagttc cattgttcct tccctgccat
    32281 atctgctcga cgggctggtg atcacgctga aaatcaccgt cacggcagtg gtgattggta
    32341 ttttgtgggg caccatgctg gcggtgatgc gcttgtccag ctttgcgccc gtagcgtggt
    32401 ttgccaaagc ctacgttaac gtattccgct cgattccttt agttatggtt ttgctgtggt
    32461 tttacctgat cgtaccgggt tttctgcaaa acgtgctggg attatcaccc aaaaatgata
    32521 tccgtttaat ttcggcgatg gtggcgtttt cgatgtttga agcggcctac tattcagaga
    32581 ttatccgtgc tggtattcaa agtatttctc gtggtcagtc gagcgccgcg ctggcgttgg
    32641 gaatgactca ctggcagtcg atgaaactga ttattctgcc gcaggcgttc cgcgcgatgg
    32701 tgccgctgtt gctcactcag ggcatcgtac tgtttcagga tacctcactg gtgtatgtgt
    32761 tatctctggc cgatttcttc cgtaccgcct caaccattgg tgagcgtgat ggtacgcagg
    32821 ttgagatgat cctgtttgcc ggatttgttt atttcgttat tagccttagc gcgtcgttgt
    32881 tggtcagcta cttgaaaaga aggacagcat aatgattacc ctgaaaaatg tttcaaaatg
    32941 gtatggtcac tttcaggtgc tgaccgactg ctcaaccgaa gtgaaaaaag gcgaagttgt
    33001 ggtggtttgc ggcccgtctg gttccggcaa atcaacgctg attaaaaccg tcaacggcct
    33061 cgaaccggtg cagcaaggtg aaatcaccgt cgatggcatc gtggttaacg acaagaaaac
    33121 cgatctggcg aaactgcgtt cccgcgtcgg gatggtgttt cagcatttcg agctgttccc
    33181 ccatctgtcg attatcgaaa acctgaccct ggcgcaggtg aaagtgctta aacgcaataa
    33241 agcgccggct cgtgaaaaag cattgaaatt gctggagcgc gtcgggcttt ccgcacatgc
    33301 caataagttt ccggcgcagc tttccggcgg ccagcagcag cgtgtggcga tcgctcgcgc
    33361 attgtgcatg gatcctattg ccatgctgtt cgacgaacca acgtcggcgc tggatccgga
    33421 gatgatcaac gaagtgctgg acgtgatggt cgaactggcg aacgaaggaa tgacgatgat
    33481 ggtggtgacc cacgaaatgg gctttgcccg taaagtggcg aatcgggtga tctttatgga
    33541 cgagggtaaa attatcgaag actcgccgaa agacgctttc ttcgataatc cgaaatcgga
    33601 ccgcgcaaaa gacttcctcg caaaaatcct gcattaatca ctctggcgcg catactcaat
    33661 tgcgcgccat ctcacgcttt ctcgtttcgt ccctcgtatc tgttacatcc cggcgttacc
    33721 cttgtcgcaa agaaacacac aacaaggagc aacaatggca ctgccaattc tgttagattg
    33781 cgacccaggt catgacgacg ctatcgcaat agttctcgcc ctcgcctcac cagagcttga
    33841 tgtcaaagca attacgtctt ccgccggaaa ccagacacca gaaaaaacct tacgcaatgt
    33901 tctgcgtatg ctgaccttgc ttaatcgcac cgatattccg gtagcaagcg gtgcggtaaa
    33961 accgttaatg cgtaatttga ttattgcgga caacgtgcac ggcgaaagcg gcctggacgg
    34021 cccggcattg ccggaaccgg catttgcacc gcaaaactgc acggcagtgg agctgatggc
    34081 gaaaacgctg cgtgaaagtg cggaacctgt caccattgtt tctaccggac cgcaaactaa
    34141 cgttgccttg ctgctcaata gccacccgga actgcatagc aaaattgccc gtatcgtgat
    34201 tatgggcggc gcaatggggc ttggtaactg gacgcctgcg gctgaattta atatttacgt
    34261 tgacccggaa gcggcagaaa ttgtcttcca gtcaggaatt ccggtggtga tggccggtct
    34321 ggatgttact cacaaagcac aaatccacgt tgaagacact gagcgtttcc gcgcgattgg
    34381 caaccctgtt tcaaccattg ttgccgaact gctggatttc ttcctcgaat atcacaaaga
    34441 cgaaaaatgg ggctttgtcg gcgcaccact gcatgaccca tgcaccatcg cctggctgtt
    34501 gaaaccggag ttgtttacca ctgttgagcg ctgggttggc gtggaaacac aagggaaata
    34561 tacccagggt atgacagttg ttgattatta ttatctgact ggcaataaac cgaatgccac
    34621 cgtaatggtc gatgttgatc gtcagggctt tgttgattta ctggctgatc gtctgaaatt
    34681 ttacgcttaa catacgtcat tgattaagat caccacgcat tacctgggtg gtcttaatct
    34741 ggttatctct ttttctttca agatataaat gcaatggata atgcagaact tgctattggt
    34801 atcgatctcg gtactaccaa tagtttaatt gccgtctgga aagacggtgc cgcgcaatta
    34861 attccaaata agttcggtga atatttaaca ccatccataa ttagcatgga tgaaaataat
    34921 catattttag tcggaaaacc ggctgtatca cggcggactt cgcatccgga taaaacggca
    34981 gcgttattta aacgtgcaat gggcagtaat accaactggc ggttaggcag cgacacattt
    35041 aacgcgccag aactgtcctc tttggtatta cgctcattaa aagaagatgc cgaagaattt
    35101 ctgcaacgtc cgattaaaga tgtggtgatc tccgttcctg cttatttcag cgatgaacaa
    35161 cgcaagcata cccgtttagc agcagagtta gccgggctaa atgcagtgcg cctgattaat
    35221 gagccaacgg cagccgcgat ggcgtatggc ctgcatacgc agcaaaatac ccgctcgctg
    35281 gtttttgatc tcggtggcgg cacgttcgac gttacggtgc tcgagtacgc cacgccggtg
    35341 attgaagtta acgcctccgc tggcgataac ttcctcggtg gcgaagattt tacccatatg
    35401 ctggtcgatg aggttttaaa acgcgcggaa gttgccaaaa ccacgcttaa cgatagcgaa
    35461 ctggcagcct tgtacgcctg cgtggaagcg gcaaaatgta gcaatcaatc gccaatgcac
    35521 attcgctggc agtaccagga tgaaatgcgg aaatgcgaat tttacgagaa cgaactggaa
    35581 gatttgtggt tgccgctgct caatcgcttg cgagtgccga ttgaacaggc gttgcgcgat
    35641 gcacgtctga agccgagtca aatcgacagt ctggtgctgg ttggcggcgc gtcacaaatg
    35701 ccgctggtgc agcgaatcgc agtgcgtctg tttggcaaat taccgtatca aagttacgat
    35761 ccgagcacca ttgtcgcgct gggcgcagca atccaggccg cctgccgctt acgcaatgaa
    35821 gatattgaag aagtgatcct cactgatatt tgcccttact cgttgggtgt tgaagttaac
    35881 cgtcagggcg tatccggcat tttctcgccg attattgaac gaaacaccac agtaccggtg
    35941 tcgcgtgtag aaacttattc aaccatgcac ccggaacagg attcaattac ggttaacgtc
    36001 tatcagggag aaaaccacaa agttaaaaat aacattcttg tggaatcctt cgatgtgccg
    36061 ttgaagaaaa ccgggactta tcagtcgatt gatattcgct ttagttatga tatcaacggc
    36121 ttgcttgaag ttgacgtgct tctggaagac ggcagcgtta agtccagagt gattaatcac
    36181 agtccggtaa cattgagcgc gcagcagatt gaagagagtc ggacgcggtt atccgcattg
    36241 aaaatttatc cgcgcgatat gctcatcaat cgcaccttta aagccaaact ggaagagttg
    36301 tgggcgcggg cgctgggtga cgagcgagaa gagattggtc gggtgatcac cgattttgat
    36361 gcggcgttgc agtcaaacga tatggcccgc gtggatgaag ttcggcggcg ggcgagcgat
    36421 tatttagcca ttgagatccc ataaacacgg ctaccggatg cggcgtaaac gctgcatccg
    36481 gcatcggcgc aaaaaacaca tcgtcaacta aacaacatcg cgattttgcc gagagcataa
    36541 cctatcacca gcaccgttaa actgattttg ataatgctgg taatgctctg tggtttttca
    36601 tcctcatcat ttatttcttc atggttttca ggtgttggct catcgacatc ttcatcctcc
    36661 ggctcgagct tcactttcgt caacagcatt cgggtgataa tggtctctaa tggatgtgcc
    36721 tctccgcgtt ccagccgcgc gtccagacgg gccagcatct cttgtttcgg aaacgcttca
    36781 agtactacct gttccgctac ccgatacaaa tccagtaacg gtgaatcttg ctctgtctcg
    36841 ctaccgactc tcgatttcca ccacgcccat gctttgcgtt tgaagaataa cgactcaata
    36901 aacgattgac ctaacggcga taattttccg ctatgtaaaa tctccgccca taacagccgc
    36961 gtccgggcgc tctcaccagg aacatatttc aacggcttac cttgcgcatc taccatgctc
    37021 cgcgcttcga taaccatcac taataacgcg aaataatccg ggcaatgacg cttgctccac
    37081 tgcaacaaca aattatcggc ttgtgtagat gggtaacttt cccggtacgc gcagagatcg
    37141 gcaagcaggc tttccccctc gccgcagtac aaccgttgtg cgcactggta ataacgggca
    37201 tcttcgcttt ctggttcttc cgcttgccac tgttgagcga caggaatgag ttccgccata
    37261 cctgtttgca ccgagctgta ccagcgcaac agtttgcgat gcaacttcgc atcatcagga
    37321 atgaaccacg gaccttccat cgccaaaaac gcagtgacat agtcaggatg gtaacggcag
    37381 caacgttcca gcgagaagta atactcaacc gtctggttct gcaacgcaac gggatattcc
    37441 agaaggctaa ggaaatcgaa acaatcacca gcctgaatgg cctcaagaaa agcctccctt
    37501 tcttcctcat ctattccttc gcagtcatta aacgaatgcc agttcaaacg ctctgccagc
    37561 aaagaagcac aatttaatga aagatatcgc gcttctatag cgattgcaca cagcggccag
    37621 cgtaattgat cgacatcctc catgttccag gtatttaatt gctgaataaa tttctgccag
    37681 gcggagggct gaaaacgatc attttctgaa tccagtaatg ccctgaatac acgtagtatt
    37741 tcatgctcag tggcagcatc tttttcttca tcatctgctt cctcgacagg atttaccgcc
    37801 agtcgcagcg cctcttcata ggcctggcgt aatgctttaa acccttgtgg atcggtttcg
    37861 ggatgacata acggtaagcg agcaagataa gcctggcgga taatgtctat ttgcgtcgtg
    37921 ctttcaattt cgaggatttg ccaacatgtt ttcataggtc gctcacatcc ttaagcgtta
    37981 ccgggcattc aggctggaca gttaatggct gccagggaag cgtggcatag aaacggtcgc
    38041 ttcccgctgc cagctcttcg aacatccgac tcccggcgct atcgtatttg tacagggtta
    38101 gcgcctcgcg tagcgaagcg ttgtcttcgc actgagaaga ttgccagtag agacgcccta
    38161 acgaataggc agaaaaatag tgcatccagc tgtgatagta atggtgtgct cgtatataga
    38221 cgcgcgattg cagccataaa ctctcgtctt ccgtcaacca cttgttgagc acaccaaccc
    38281 gtgataaaaa acccatccgc acataatccc aggctttgat tcccccttcc ccacaacaca
    38341 tagcggtttg ggcaacgaat tgggtataaa tcaaccctct ctccgagccg ccagcaatta
    38401 atgctttcca ctcttcaggg gaagagcgat gccatgtcag atataagcca gctaaatcat
    38461 tggcatgacc atcatcggtc atctgataaa tagtctgaat taaatcatca cgattattta
    38521 ttccccagga tgatgagaga tcgaattctt ttatcccggt atacattttt ggcgagtcat
    38581 gcgcgggctt gcaaccctga ttaagtattt ccatgggcgt agaaagcgca aaaagaagat
    38641 attgttcttc cttattcatt tgttaataat cccttaagtg cattaactga ctactttttt
    38701 attattgatg agtataaact tgacgctttc aaaataaaaa gaaaatcgaa gcattcacac
    38761 atgaataaaa aattaatgta tatattcgca atatttatag ttgcagcaat aacctgtatt
    38821 agccaaccca agaaaacgac gttgcgtgat aaagccatgg cgaattatgc ctttgattat
    38881 ttaagctcac cgggcagtct tccattcacc acggcagcca cggagctttc cgcgattcat
    38941 ggtcactcaa cgtcgcaata tcgccttgga gaattttatc ttcatggtag cgacggtaaa
    39001 ccactggatt atacacaggc gagatactgg tatgagcaat cagcagaaca ggaaaatcca
    39061 cgcgcgcaaa gtaaactggg gtggatctac ctcaaaggtc tgggggtcaa acccgacacc
    39121 cgtaaagcaa ttctctggta taaggaagca gctgaacaag ggtatgctca tgctcaatat
    39181 actttgggtt tgatctacag aaatggctca ggtattaatg ttaaccatta tgaatctcaa
    39241 aaatggttaa aactggccgc caaacaacat tacaaaaatg cggaaagatt acttgccggg
    39301 ctttccgcac attaacgtcg actgtcaccc gaacagatgg agtattttcc ctatcaaacc
    39361 agcaaagata aaaatataga aaataatttt aatgatgccc agacagcctg gcccaccatc
    39421 gtcaacgggc attggctgcg gttgcggctc cgataacgct ggcgaagggg tggaccagga
    39481 ctataagcaa gcgatgtact ggtatctgaa ggctgctgct caggaaagcg tcggcgctta
    39541 cgtcaacatc ggttatatgt ataaacacgg acaaggcgtt gagaaagatt atcaggccgc
    39601 ctttgaatag tttacgatag ccgctgaatg caatgacgcc acagcctggt ataacctggc
    39661 cattatgtat cactacggag aaggaagacc tgtcgatctc cgacaggctc tcgacttgta
    39721 tcgtaaagtt cagtcatccg gaaccagaga tgtcagtcaa gaaattcgtg agattgaaga
    39781 tttactgtag agataaaaac aagggccggg gaatttcatt cggcccatat tctctttatt
    39841 gctgtgcgaa atcagactat tacggctcaa acgggcgtct ctggaactgg tcatgaccac
    39901 atttagggca tagcgtcagc acttccggtg tgtagatcgg gagatggaag tgacatttct
    39961 cgcagaccag atttcccagc cctaccactt ctccgctgtg ataaacccca tgatgattga
    40021 ggtcctggaa aacttcgcgc cattcaagct gcgttttatc ggtgatgtct gccagctcct
    40081 gccacaagct ttctttaatc acccgcataa agacgctgtc agactcttct ttcaggctct
    40141 cttcatagct catggcgaac tcttccaggt cacgtctgac agctcgcgtc agctcatcga
    40201 cctcggttcg cgttaactcc cctgttttta ttacgcgctc gcgcgcctgt tccaccagtg
    40261 cgtcgatatc acgttcgcca ttgcgcaggc gttcgctcag tgacgcgacc agttcacggt
    40321 aatattgagc aaccttgttc atcgtttcat ctcccgggtc gttaactgac tataataata
    40381 gacgttcttt gttccttgct ttgctaatac gcccacaaac tctgtaaatt aatgtatgaa
    40441 taatccgggc atcatttcaa cgtcgagtgc gcgaaaggct gttttgacgc gggcgtttgg
    40501 gctatgctat gcggatctga aaaaccacat caacgctaca tttgtagccg tattgaaaac
    40561 aggaccactg gctgccatgc aagagcaata ccgcccggaa gagatagaat ccaaagtaca
    40621 gcttcactgg gatgagaagc gcacatttga agtaaccgaa gacgagagca aagagaagta
    40681 ttactgcctg tctatgcttc cctatccttc tggtcgacta cacatgggcc acgttcgcaa
    40741 ctacaccatc ggtgacgtga tcgcccgcta ccagcgcatg ctgggcaaaa acgttctgca
    40801 gccaatcggc tgggacgcat ttggtctgcc tgcggaaggc gcggcggtga aaaacaacac
    40861 cgcgccagca ccgtggacgt acgacaacat cgcgtatatg aaaaaccagc tcaaaatgct
    40921 gggctttggt tatgactgga gccgcgagct ggcgacctgt acgccggaat actaccgttg
    40981 ggaacagaaa ttcttcaccg agctgtataa aaaaggcctg gtatataaga agacttctgc
    41041 ggtcaactgg tgcccgaacg accagaccgt actggcgaac gaacaagtta tcgacggctg
    41101 ctgctggcgc tgcgatacca aagttgagcg taaagagatc ccgcagtggt ttatcaaaat
    41161 cacagcttac gctgacgagc tgctcaacga tctggataaa ctggatcact ggccagacac
    41221 cgttaaaaca atgcagcgta actggatcgg tcgttccgaa ggcgtggaaa tcaccttcaa
    41281 cgttaacgac tatgacaaca cgctgaccgt ttacactacc cgcccggaca cctttatggg
    41341 ttgtacctac ctggcggtgg ctgcgggtca tccgctggca cagaaagcgg cggaaaataa
    41401 tcctgaactg gccgccttta ttgacgaatg ccgtaacacc aaagttgccg aagctgaaat
    41461 ggcgacgatg gagaaaaaag gcgtcgatac tggctttaaa gcggttcacc cattaacggg
    41521 cgaagaaatt cccgtttggg cagcaaactt cgtattgatg gaatacggca cgggcgcagt
    41581 tatggcggtt ccgggtcacg accagcgcga ctacgagttt gcctctaaat acggcctgaa
    41641 catcaaaccg gttatcctgg cagctgacgg ctctgagcca gatctttctc agcaagccct
    41701 gactgaaaaa ggcgtgctgt tcaactctgg cgagtttaat ggtcttgacc atgaagcggc
    41761 cttcaacgcc atcgccgata aactgactgc gatgggcgtt ggcgagcgta aagtgaacta
    41821 ccgcctgcgc gactggggtg tttctcgtca gcgttactgg ggcgcgccga ttccgatggt
    41881 gacgctggaa gacggtaccg taatgccgac cccggacgac cagctgccgg tgatcctgcc
    41941 ggaagatgtg gtgatggacg gcattaccag cccgattaaa gcagatccgg agtgggcaaa
    42001 aactaccgtt aacggtatgc cagcactgcg tgaaaccgac actttcgaca cctttatgga
    42061 gtcctcctgg tactatgcgc gctacacttg cccggagtac aaagaaggta tgctggattc
    42121 caaagcggct aactattggc tgccggtgga tatttacatt ggtggtatcg aacacgccat
    42181 tatgcacctg ctctacttcc gcttcttcca caaactgatg cgtgatgcag gcatggtgaa
    42241 ctctgacgaa ccagcgaaac agttgctgtg tcagggtatg gtgctggcag atgccttcta
    42301 ctatgttggt gaaaacggcg aacgtaactg ggtttccccg gttgatgcta tcgttgaacg
    42361 tgacgagaaa ggccgtatcg tgaaagcgaa agatgcggca ggccatgaac tggtttatac
    42421 cggcatgagc aaaatgtcca agtcgaagaa caacggtatc gacccgcagg tgatggttga
    42481 acgttacggc gcggacaccg ttcgtctgtt tatgatgttt gcttctccgg ctgatatgac
    42541 tctcgaatgg caggaatccg gcgtggaagg ggctaaccgc ttcctgaaac gtgtctggaa
    42601 actggtgtac gagcacacag caaaaggtga tgttgcggca ctgaacgtcg atgcgctgac
    42661 tgaagatcag aaagcgctgc gtcgcgatgt gcataaaact atcgctaaag taaccgatga
    42721 tatcggccgt cgtcagacct tcaacaccgc aattgcggcg attatggagc tgatgaacaa
    42781 actggcgaaa gcaccgaccg atggcgagca ggatcgcgcc ctgatgcagg aagcgctgct
    42841 ggcggtagtc cgtatgctta acccgttcac cccgcacatc tgcttcacgc tgtggcagga
    42901 actgaaaggc gaaggcgata tcgacaacgc gccgtggccg gttgctgacg aaaaagcgat
    42961 ggtggaagac tccacgctgg tcgtggtgca ggttaacggt aaagtccgtg caaaaatcac
    43021 cgttccggtg gacgcaacgg aagaacaggt tcgcgaacgt gctggccagg aacatctggt
    43081 agcaaaatat cttgatggcg ttactgtacg taaagtgatt tacgtaccag gtaaactcct
    43141 caatctggtc gttggctaag cgcgggagga agcgtgcgat atctggcaac attgttgtta
    43201 tctctggcgg tgttaatcac cgccgggtgt ggctggcatc tgcgtgacac cacgcaggtt
    43261 ccttccacta tgaaagtcat gatcctggac tcaggcgatc cgaacgggcc attaagccgt
    43321 gcggtgcgta accagttacg tctgaatggt gtcgagttgc ttgataaaga aaccacgcgt
    43381 aaggacgttc catccctgcg tttgggtaaa gtgagcatcg cgaaagatac cgcatcggta
    43441 ttccgtaacg gtcaaacagc agagtatcag atgatcatga cggtgaatgc gaccgtgttg
    43501 atccccggcc gtgacatcta cccgattagc gccaaggtct tccgttcgtt cttcgataac
    43561 ccgcaaatgg cgttagcgaa agataacgaa caagacatga tcgtaaaaga gatgtacgac
    43621 cgtgctgccg aacagctgat tcgtaagctg ccaagcatcc gtgctgcaga tattcgttcc
    43681 gacgaagaac agacgtcgac cacaacggat actccggcaa cgcctgcacg cgtctccacc
    43741 acgctgggta actgatgatt cggttgtacc cggaacaact ccgcgcgcag ctcaatgaag
    43801 ggctgcgcgc ggcgtatctt ttacttggta acgatcctct gttattgcag gaaagccagg
    43861 acgctgttcg tcaggtcgct gcggcgcaag ggttcgaaga acaccacact ttttccattg
    43921 atcccaacac cgactggaat gcgatttttt cgttatgcca ggccatgagc ctgtttgcca
    43981 gtcgacaaac gctattgctg ttgttacccg aaaacggacc gaatgcggcg atcaatgaac
    44041 aacttctcac actcaccgga cttctgcatg acgatctact gttgatcgtc cgcggtaata
    44101 aattaagcaa agcgcaagaa aatgccgcct ggtttactgc tcttgcgaat cgcagcgtgc
    44161 aggtgacctg tcagacaccg gagcaggctc agctgccccg ctgggttgct gcgcgcgcaa
    44221 aacagctcaa cttagaactg gatgacgctg caaatcaggt gctctgctac tgttatgaag
    44281 gtaacctgct ggcgctggcc caggcactgg agcgtttatc gctactctgg ccggacggca
    44341 aactgacatt accgcgcgtt gaacaggcgg tgaatgatgc cgcgcatttc accccttttc
    44401 attgggttga tgctttgttg atgggaaaaa gtaagcgcgc gttgcatatt cttcagcaac
    44461 tgcgtctgga aggcagcgaa ccggttattt tgttgcgcac attacaacgt gaactgttgt
    44521 tactggttaa cctgaaacgc cagtctgccc atacgccact gcgtgcgttg tttgataagc
    44581 atcgggtatg gcagaaccgc cggggcatga tgagcgaagc gttaaatcgc ttaagccagc
    44641 cgcagttacg tcaggccgtg caactcctga cacgaacgga actcaccctc aaacaagatt
    44701 acggtcagtc agtgtgggca gagctggaag ggttatctct tctgttgtgc cataaacccc
    44761 tggcggacgt atttatcgac ggttgatatg aaatctttac aggctctgtt tggcggcacc
    44821 tttgatccgg tgcactatgg tcatcttaaa cccgtggaaa cgctggcgaa tttgattggt
    44881 ctgacgcggg tcacaatcat ccctaataat gttcctccgc atcgtcccca gccggaagcg
    44941 aacagcatgc agcgtaaaca catgcttgaa ctggcgattg ccgacaagcc attatttact
    45001 cttgatgaac gcgagctaaa gcgcaatgcc ccctcttaca ctgcgcaaac actgaaagag
    45061 tggcggcagg aacaaggacc ggacgtgccg ctggcgttta ttattggtca ggattcattg
    45121 ctgacctttc cgacctggta cgaatacgaa acgatactcg acaatgcaca tttgatcgtc
    45181 tgtcggcgtc caggttaccc acttgaaatg gcgcaaccgc aataccagca atggctggaa
    45241 gatcatttga cacataaccc ggaagatctt caccttcagc ctgccggtaa aatttatctg
    45301 gctgaaacgc cgtggtttaa catctcggcg accatcatcc gcgaacgttt gcaaaacggt
    45361 gaatcgtgtg aggatttatt accggaaccg gtactgactt acattaacca acaaggcttg
    45421 tatcgctgat acctgtcgtt acggagggca tgatgcgact gtggttaatt cgtcatggtg
    45481 aaacgcaagc gaatgtcgat ggtctgtaca gcggtcatgc gcccacaccc ctgaccgcgc
    45541 gcggtattga gcaagcgcaa aatctgcata cgctgctaca tgatgtttcc tttgacctgg
    45601 ttttatgcag tgaactggaa cgggcacagc ataccgcgcg actggttctt agtgaccgcc
    45661 agcaccccgt tcatatcatc cctgaactca atgaaatgtt ttttggcgac tgggagatgc
    45721 gacatcatcg tgacctcatg caagaagatg ccgaaaacta tagcgcgtgg tgcaatgact
    45781 ggcagcaagc tatccccacg aacggtgaag gatttcaggc attttcgcaa cgtgtggaac
    45841 gatttatcgc aaggcttagt gaatatcagc actatcagaa tattttagtc gtcagccatc
    45901 agggcgtact gagtctgtta attgctcgtt taattggtat gcctgccgag tctatgtggc
    45961 atttccgcgt tgaccagggg tgttggagcg ccattgatat caaccaaaaa ttcgcgacgc
    46021 tacgcgtcct caatagccgt gccatcgggg tcgagaatgc atgacttttc tgttttttta
    46081 cgggtaagcc gcaacgacca ttgacagccc cgggcaggct gatattctcc gcagccagac
    46141 tttttccgcc agacacgact ttgtagaaat tgttttacaa aaatggcgat gcaatctgcg
    46201 gcgcggggtg ggatgatagc ccactttcga aagccgattc ggcgacaatt gtcccgaaat
    46261 cgcctctggt tcaggtatac tgacagacca tttttatcta tttgattcac ccagggggaa
    46321 aacttgcagg gtaaagcact ccaggatttt gttatcgaca aaattgatga cctcaaaggt
    46381 caggacatca tcgccttaga cgttcagggc aaatccagca tcaccgactg catgatcatc
    46441 tgtacgggta cgtccagccg ccatgttatg tccattgctg atcacgttgt gcaggagtct
    46501 cgcgcagcgg gcctgttacc gctcggcgta gaaggtgaaa acagcgccga ctggattgtc
    46561 gtggatttgg gcgatgtgat tgtccatgtc atgcaggaag agagccgtcg cctgtatgaa
    46621 ctggaaaaac tctggagtta atgcgtgaag ctgcaacttg tcgccgtggg aacgaaaatg
    46681 ccggactggg tacaaaccgg ttttaccgag tacctgcgtc gttttccgaa agatatgccc
    46741 ttcgagctga ttgaaattcc ggccggaaaa cgcggcaaga atgcggacat caagcgcata
    46801 ctcgacaaag agggtgagca gatgttggcg gccgcaggca aaaaccgcat tgtcaccctc
    46861 gatattccag gcaagccctg ggatacgccg cagttagccg ctgagctgga acgctggaag
    46921 ctggatggtc gcgacgtcag tctactgatt ggcgggcctg aagggttgtc gcctgcctgt
    46981 aaagcggcgg cggagcagag ctggtcgctg tcggcactta cccttcccca tccgctggtt
    47041 cgcgtgctgg tcgcagagag tctgtaccgg gcgtggagca tcaccaccaa ccatccttat
    47101 caccgtgagt gataagtgag ctttgagtag aaaacgcagc ggatgaaact acagaactct
    47161 tttcgcgact atacggcaga gtccgcgctg tttgtgcgcc gggcgctggt cgcctttttg
    47221 gggattttgc tgctgaccgg cgtgcttatc gccaacctgt ataatctgca aattgttcgc
    47281 tttaccgact accagacccg ctctaatgaa aaccgcatta agctggtgcc tatcgcaccc
    47341 agccgcggca ttatctacga ccgtaacggt atccctctgg ctctcaaccg cactatctac
    47401 cagatagaaa tgatgccgga gaaagtcgat aacgtgcagc aaacgctgga cgctttgcgc
    47461 agcgtggttg atctgaccga tgatgatatt gctgcattcc gaaaagagcg cgcacgttca
    47521 caccgtttca cctctattcc ggtgaaaact aacctgaccg aagtacaagt agctcgcttt
    47581 gccgtcaacc agtaccgttt tccgggtgtt gaagttaaag gctataaacg tcgttactat
    47641 ccttacggtt cggcgttgac ccacgtcatc ggctatgtgt cgaaaatcaa cgataaagac
    47701 gtcgaacgcc tgaataatga cggcaaactg gccaactatg cggcaacgca tgatatcggt
    47761 aagctgggca ttgagcgtta ctatgaagac gtgctgcacg gtcagaccgg ttatgaagag
    47821 gttgaagtta acaaccgtgg gcgtgttatc cgccagttaa aagaagtacc accgcaggcc
    47881 ggacacgata tttacctgac gctggatctc aaactccagc aatatattga aacgctgctg
    47941 gcgggtagcc gcgcagctgt ggtagtcacc gatccgcgta ccggtggggt gttggcgctg
    48001 gtttccacgc ctagttatga cccaaacctg tttgttgacg gtatctccag caaagattat
    48061 tccgccttgc tgaacgaccc gaatacaccg ctggtgaacc gcgccacaca gggggtttat
    48121 cctcccgcgt ctacagttaa accctatgtg gcggtttcgg cattgagcgc cggagtgatc
    48181 acgcgcaata cgacgttgtt tgaccccggc tggtggcaac ttccaggttc ggaaaaacgt
    48241 tatcgtgact ggaaaaaatg gggccacggg cgtctgaatg tcacaagatc gctggaagaa
    48301 tctgcggata ccttcttcta tcaggtggcc tacgatatgg ggatcgatcg cctctccgaa
    48361 tggatgggta aattcggtta tggtcattac accggtatcg acctggcgga agaacgttcc
    48421 ggcaacatgc ctacccgcga atggaaacag aaacgcttta aaaaaccgtg gtatcagggt
    48481 gacaccattc cggttggtat cggtcagggt tactggacag cgaccccaat ccagatgagt
    48541 aaggcactga tgatcctgat taatgacggt atcgtgaagg ttccgcattt gctgatgagc
    48601 accgccgaag acggcaaaca ggtgccatgg gtacaaccgc atgaaccgcc cgtcggcgat
    48661 attcattccg gttactggga gctggcgaaa gacggtatgt acggtgttgc taaccgccct
    48721 aacggtacgg cgcataaata ttttgccagc gcaccgtaca aaattgcggc gaaatccggt
    48781 accgctcagg tcttcggtct gaaagcgaac gaaacctata atgcgcacaa aattgccgag
    48841 cgtttacgtg accacaaact gatgaccgcc tttgcgccat acaacaatcc gcaagtggct
    48901 gtcgccatga ttctggagaa cggtggcgcg ggtccggcgg ttggtacgct gatgcgccag
    48961 atcctcgacc acattatgct gggtgataac aacaccgatc tgcctgcgga aaatccagcg
    49021 gttgccgcag cggaggacca ttaatcatga cggataatcc gaataaaaaa acattctggg
    49081 ataaagtcca tctcgatccc acaatgctgc tgatcttact ggcattgctg gtttacagcg
    49141 ccctggttat ctggagcgcc agcggtcagg atattggcat gatggagcgt aaaatcggcc
    49201 agattgcgat gggtctggtc atcatggtgg tgatggcgca aattcctcca cgcgtttatg
    49261 aaggctgggc cccctatctc tatatcatct gtattatttt gctggtggcg gtagatgctt
    49321 tcggtgccat ctctaaaggc gctcaacgct ggctggacct cggtattgtt cgttttcaac
    49381 cgtcggaaat tgccaagata gccgtaccgt tgatggttgc acgctttatc aaccgcgacg
    49441 tttgcccacc ttcattgaag aatacagcta tcgcgctggt gctgatattt atgcccacgc
    49501 tgctggtggc tgcacagcct gacctgggaa catcaatcct cgttgcgctt tccggcctgt
    49561 ttgtactgtt cctctctggc cttagctggc gtctgattgg cgtcgcagta gtgctggtag
    49621 cggcgttcat tccgattctg tggttcttcc tgatgcatga ttaccagcgc cagcgcgtaa
    49681 tgatgctcct ggacccggaa tcagacccac tcggcgcagg ctatcacatt attcagtcta
    49741 aaattgctat tggctccggc ggattacgcg gcaaaggctg gctgcacggc actcagtcac
    49801 agcttgaatt tctccccgaa cgccataccg actttatctt cgcggtactg gcggaagagc
    49861 tgggattagt gggcattttg attctgctcg ctctctacat tctgctgatc atgcgcgggc
    49921 tgtggatagc cgccagagcg caaaccacct ttggtcgcgt catggctggc ggcttaatgc
    49981 tgatattatt cgtttatgtc ttcgtaaata ttggtatggt aagcggtatt ctgccggttg
    50041 taggggttcc gctcccactg gtcagttatg gaggatcggc gctaattgtg ctgatggctg
    50101 ggttcgggat tgtaatgtca atccacaccc acaggaaaat gttgtcgaaa agcgtgtaag
    50161 aggtgcgcaa tgcgtaagca gtggctcggg atctgcatcg cggcaggaat gctcgcggca
    50221 tgtacaagcg atgatggtca gcaacagacg gtaagtgtac cgcagcctgc ggtatgtaac
    50281 ggccccatag ttgaaattag cggggcagac ccgcgtttcg aaccactgaa cgcgacggca
    50341 aatcaggatt accagcgcga cggtaaaagc tacaaaatcg tgcaggatcc gtctcgattt
    50401 agccaggcgg gactggcggc aatctatgat gccgaacccg gcagtaacct gacggcctct
    50461 ggcgaagctt tcgatccgac acagttgacg gcggcccatc caacgcttcc gatccccagc
    50521 tacgccagaa tcactaacct ggctaacggg cgaatgatcg tggtgcgcat taatgatcgc
    50581 ggcccttatg gcaacgaccg cgtgatttcg ctttctcgcg cggcagctga ccgtcttaac
    50641 acgtcaaaca acaccaaagt tcgtatcgat ccgattattg tcgcccagga tggttcgctt
    50701 tctggtcctg gtatggcttg taccacagtc gccaaacaga cttacgccct gccagcacct
    50761 cccgatttaa gcggtggcgc gggaacaagt tcagtgcctg tcccgcaggg tgacattctt
    50821 ccggtcagta attcgacgct aaaaagcgaa gatccgaccg gcgcgccggt aaccagcagc
    50881 ggtttcctcg gcgcaccaac gaccttagcg cctggtgtac tggaaggcag cgaaccgacg
    50941 cctgcgccac agcccgttgt tacagctccg tcgacaacgc ctgcaacctc acctgcaatg
    51001 gtgacaccgc aagccgcctc gcaaagcgcc agcggcaact ttatggtgca agtcggggcc
    51061 gttagcgatc aggctcgtgc gcaacagtac caacagcaac tgggacagaa gttcggcgtc
    51121 cccggtcgcg taactcaaaa tggcgcggtc tggcggatcc agcttggccc attcgccagc
    51181 aaagccgaag ccagtacctt gcagcaacgt ttgcaaaccg aagcccaatt acagtcattt
    51241 attaccaccg cgcagtagcg taaagcaggc atctgatgtg tcaatttctg taaatgacgt
    51301 taacaaagtc acgcggaaag tcagatgcct gccggtagtg catttgctat agtagggcac
    51361 tttttttaat tccatcacgg atgtcgtagt tcagaccatg aataccattt tttccgctcg
    51421 tatcatgaag cgcctggcgc tcaccacggc tctttgcaca gcctttatct ctgctgcaca
    51481 tgccgatgac ctgaatatca aaaccatgat cccgggtgta ccgcagatcg acgcggagtc
    51541 ctacatcctg attgactata actccggcaa agtactcgcc gaacagaacg ctgatgtccg
    51601 ccgcgatcct gccagcctga ccaaaatgat gaccagttac gttatcggcc aggcaatgaa
    51661 agccggtaaa tttaaagaaa ctgatttagt cactatcggc aacgacgcat gggccaccgg
    51721 taacccggtg tttaaaggtt cttcgctgat gttcctcaaa ccgggcatgc aggttccggt
    51781 ttctcagctg atccgcggta ttaacctgca atcgggtaac gatgcttgtg tcgccatggc
    51841 cgattttgcc gctggtagcc aggacgcttt tgttggcttg atgaacagct acgttaacgc
    51901 cctgggcctg aaaaataccc acttccagac ggtacacggt ctggatgctg atggtcagta
    51961 cagctccgcg cgagatatgg cgctgatcgg ccaggcgttg atccgtgacg taccgaatga
    52021 atactcgatc tataaagaaa aagaatttac gtttaacggt attcgccagc tgaaccgtaa
    52081 cggcctgtta tgggataaca gcctgaatgt cgacggcatc aaaaccggac acactgacaa
    52141 agcaggttac aaccttgttg cttctgcgac tgaaggccag atgcgcttga tctctgcggt
    52201 gatgggcgga cgtactttta aaggccgtga agccgaaagt aaaaaattgc taacctgggg
    52261 cttccgtttc ttcgaaaccg ttaatcctct gaaagtaggt aaagagttcg cctctgaacc
    52321 ggtttggttt ggtgattctg atcgcgcttc gttaggggtt gataaagacg tgtacctgac
    52381 cattccgcgt ggtcgcatga aagatctgaa agctagctat gtgctgaaca gcagtgaatt
    52441 gcatgcgccg ctgcaaaaga atcaggtcgt cggaactatc aacttccagc ttgacggcaa
    52501 aacgatcgaa caacgcccgc tggttgtgct gcaagaaatc ccggaaggta acttcttcgg
    52561 caaaatcatt gattacatta aattaatgtt ccatcactgg tttggttaaa aattgaacac
    52621 ttgaaagtgt aatttccgtc cccatatact aagcatcagt aaaaaactcc cgccttctgg
    52681 cgggagttgc tatttaatta cgttacgccg gagctgacat gaaaaccaaa cttaacgaac
    52741 tgcttgaatt ccctactcct tttacttaca aagttatggg gcaggcgtta cctgagctgg
    52801 ttgatcaggt ggttgaagtg gtacagcgcc atgcgccagg tgactacacc ccaacggtaa
    52861 aaccaagcag caaaggcaac taccactcgg tatctatcac tatcaacgcc actcatatcg
    52921 agcaggttga aacactgtat gaagaactgg gcaaaatcga tattgtccgc atggttctgt
    52981 aactcgcttc tccgttaccc ggctcctggt cgggtaactc ccctctcctc gctgtgatat
    53041 acttttcccc cacttttact cattctccac ggagatgccg ttttgtatca ggataaaatt
    53101 cttgtccgcc agctcggtct tcagccttac gagccaatct cccaggctat gcatgaattc
    53161 accgataccc gcgatgaaag tacccttgat gaaatctggc tggtcgagca ctatccggta
    53221 ttcacccaag ggcaggcagg aaaggcggag cacattttaa tgccgggtga tattccggtg
    53281 atccagagcg atcgcggtgg gcaggtgact tatcacgggc cggggcaaca ggtgatgtat
    53341 gtgttgctta acctgaaacg ccgtaaactc ggtgtgcgtg aactggtgac cttgcttgag
    53401 caaacagtgg tgaataccct ggctgaactg ggtatagaag cgcatcctcg ggctgacgcg
    53461 cctggtgtct atgtcgggga aaagaaaatt tgctcactgg gtttacgtat tcgacgcggt
    53521 tgttcattcc acggtctggc attaaacgtc aatatggatc tttcaccatt tttacgtatt
    53581 aatccttgtg ggtatgcagg aatggaaatg gctaaaatat cacaatggaa acccgaagcg
    53641 acgactaata atattgcacc acgtttactg gaaaatattt tagcgctact aaacaatcct
    53701 gacttcgaat atattaccgc ttaattccat acatcaatgg cccaatttac actgggtcat
    53761 tactcataat acctgctaat gctttacatc tccttcgcgt ttgtatattt tctttatcac
    53821 ttgcagaaat gcgatgctac gccttgctcc gtagcccacc taattgatta actcattgaa
    53881 ataattgacc atggtgagca aaagcgttcc gtcccaatta gacataagat tattgtaatt
    53941 tttttaaata ttattttttc atgaataaaa ttggagtaag tgcgtggata gtaataataa
    54001 aattgaaccc tgtttaagca gaaaatcgtc agaaggtaaa ccacaaatat ttacaacctt
    54061 acgaaatatt gatcttaccc ttctgactat tttgaagttg catatgtcca taaaggaatc
    54121 gttaatgcag cgaaagtgct taatctgccc cccctcggca atctatcagc ctattcagaa
    54181 actgcgcgtt atattccctg acctattgtt tattcgcaaa ggccagggtg tcactcctac
    54241 cgcatttgcg atgtatctat atgagtctat cactcaggga cttgagtcca ttcttggcgc
    54301 gctggatatc gaaggaagct atgataagca acggacgata actattgcgc cctccccctc
    54361 ggtcggagcc ctggtccttc ctgtcatcta tcgggcgatt aaaactcact atccacagct
    54421 tttactgcgc aacccgccca tcagcggcgc ggaaaaccaa ctcagtcagt ttcaaaccga
    54481 tctcatcatc aataacatgt tttgcacggg gtcatagatg ttatccgtaa tgcattttga
    54541 aaaagtattg ttacagccag atcacagcgc acaacgataa aatggcacaa tccaacaaca
    54601 attttacatt ttcgcgaccg ctttggctgc tttcaggtcc gtttcaatga tatactgcca
    54661 gtcgttaatt caaaaatagt tgataattac aacaatctat tgaattgaaa cgctttcctt
    54721 cgtaattcgc aactggaaca cgcacgctat gagtaaaccc attgtgatgg aacgcggtgt
    54781 taaataccgc gatgccgata agatggccct tatcccggtt aaaaacgtgg caacagagcg
    54841 cgaagccctg ctgcgcaagc cggaatggat gaaaatcaag cttccagcgg actctacacg
    54901 tatccagggc atcaaagccg caatgcgcaa aaatggcctg cattctgtct gcgaggaagc
    54961 ctcctgccct aacctggcgg aatgctttaa ccacggcact gcaacgttta tgatcctcgg
    55021 cgctatttgt acccgccgtt gcccgttctg tgacgttgcc cacggtcgcc cggtagctcc
    55081 tgatgccaat gaaccagtga aactggcgca gaccattgcc gatatggcgc tgcgttatgt
    55141 ggttatcacc tccgttgacc gtgatgatct gcgcgatggc ggtgcccagc actttgcgga
    55201 ttgcattact gccattcggg aaaaaagccc gcaaatcaaa attgaaactc tggtgccgga
    55261 tttccgcggt cgtatggatc gtgctctgga tattctgact gcaacgccac cagatgtgtt
    55321 caaccataac ctggaaaacg taccgcgtat ttaccgtcag gtacggcctg gtgcagatta
    55381 caactggtcg cttaagctgc tggaacgctt taaagaagcg catccggaaa tcccgaccaa
    55441 gtctggtctg atggtgggac tgggtgaaac caatgaagaa attattgagg taatgcgcga
    55501 cctgcgccgt catggtgtga cgatgctaac gctggggcaa tatttgcagc caagccgcca
    55561 tcacctgccg gttcaacgtt acgttagccc ggatgagttc gacgaaatga aagccgaagc
    55621 gctggcgatg ggctttaccc atgctgcatg cggtccgttt gtccgctctt cttaccacgc
    55681 cgatttgcag gcgaaaggga tggaagttaa gtaatcctgt aataattact tacatctgtc
    55741 tgataaaaaa cccgcttttt gaagcgggtt tttgtatcga acaagatatt gagggagcgt
    55801 cctgctcgcc acgtcactct ttatgagaga gcttttcagc ctgaagatca acgtctgcgc
    55861 cttttttcgc cgcagcatcg tcatcattca tcgccttctt gaacccttta atggccgctc
    55921 caaggtctcc gcccagcgta cgtaacttct tagtcccaaa cagcagaacg accagcgccg
    55981 caactaccag cagtttggta atactaatct cacccataga taccttcttg acatataacc
    56041 ggcaacagaa cgcgccttaa aaaccagaga atattaacgg tcattcgacg cgcgcacaca
    56101 atagcaatct gtaacaaggt gaatcaagcg ccgagtaaaa aaacatcata ataattgcgg
    56161 cggcgcaaag cgacggttgt ttaagacggg cagttgcgcg cgcacctgac gcacacgttc
    56221 gggcgtcact tccgccataa tgagtgcagg catttctgac gctgccgcaa tggtgacgcc
    56281 aaagggatct ataatccggc tttgcccgat atttttgttc ccgcactccc ccgccgccac
    56341 catataacag gtggtatcca gcgcacgagc ggcaagcaac gttgaccagt gatgctcttt
    56401 gagcggccca cgaacccagg cggcaggaag taccagtatt tcagctccct gtaatgcctg
    56461 tgccagcgcc agctctggaa agcgtaagtc ataacaggtc atcagaccga ccttcatccc
    56521 ctccacctcc agtaacggag ctatttcatt accagcatca acatggcgtg attcctgaat
    56581 ggcaaatgca tcatagagat gcagtttggc ataacgggcg acgatgtttc ctgcctgtag
    56641 cgccaccagc atattccatg cgcgccccgg tgttgaagga acatgaatcg tcagaattgt
    56701 cgtcatcatg ttacgtttac tttctcgccg taaacgaccg aggaattcgc cttccagcag
    56761 ttgtgctgat ttaaccgata gatctgcatc atgatcatca cgcgccagta atgcttccgg
    56821 caggacaaac agcgaaacct cgttttccgc cgcctgcgcc atcaacgagg cacaaatctc
    56881 aacgttcttt tcccacacag atgtaacagc aaactgtcct gcggcaacca gcattgccac
    56941 ctcctgtcag agtcgtaaaa ttcgccaacg gcgattattc ggcgttacac ttatcactca
    57001 tacaaatcaa atagcaggat tttgcagtgt tacaacttct tttagcagtt tttattggcg
    57061 gtggtacggg aagcgtggcg agatggctgt taagtatgcg atttaacccg ctgcatcagg
    57121 cgattccgtt gggaacgctg gcagcaaacc tgattggggc attcatcata ggaatgggat
    57181 tcgcctggtt cagcaggatg acgaacattg atccagtgtg gaaagtatta atcaccaccg
    57241 gattttgtgg cggtctaaca accttctcaa cattttcggc agaagtggtg tttttgttac
    57301 aagagggccg ctttggctgg gcgttactga acgttttcgt caaccttttg gggtcttttg
    57361 ccatgaccgc actggctttc tggctgtttt ccgcctcaac cgcacactaa agaccaaaaa
    57421 aaacccgctg attaagcggg ttttgaattc ttgctgacgt atcttacaga gcgattacgt
    57481 ttgcagcaga agggcctttg gcaccgttag tgatttcgaa ctctacgcgc tgaccttcag
    57541 caagagtttt aaaaccatta gtctggattg cagagaagtg tacgaacacg tctttgctgc
    57601 cgtcttccgg agtaatgaaa ccgaatcctt tggactcatt aaaccactta acgttacctt
    57661 taatcttaga catcaaaatt acctttacat gaaaaataga cacaaatgct gtgtcggtta
    57721 ccagtacacc aattgtggta cgctttgtcc agtgcaactt tactaaaaag tgataaaagt
    57781 cgcgttattt ttgatgttaa ttattttagt ggttgatttt aaagaattta ctaaaacttc
    57841 atttgtctca aaactgaaag cgcatccagg caaagtacac attgccattg ttgtaggtac
    57901 ccggaatgta ggtcatctga aacgtcgcgg ggccataccc cacagaggcc aatggcagta
    57961 gaaccggaag agggatgtaa ttccagttat cgcgcgccgt tacgccagcg gtaaatccca
    58021 ggcctaaatg aaaattttca tccgccagcg gtcgccaggt actttcccat ccgtatccgg
    58081 caatcggttc ccatttgttc cacgagtcct taaatgccat tgcatacagg ccatgccagt
    58141 ttcctttttc atcccaacgc gactgaccaa aaccgccacc ccacggtcgc tcgttatagc
    58201 gatcggtttt ttctttgtca taggcaaaac gcgcatgcca ggtgatggca ggaatatata
    58261 aatcataatg ttctggctgt tgccaggttt gtgcaatatt ttctctaaac gttgtcatcc
    58321 actcatcagc gttagcaaaa actttaccaa cactgattaa ctgaataaaa acaaagaaaa
    58381 atatagcgac atatttactc acgttcattt gtgaccatta aacatttatc aaaaatctac
    58441 tactaacata gcaaaactac aattaacata acctcaatag ccccaacatg aaaaataata
    58501 tgaatagctg ctctatttat ttccgctagt tcaagataaa tatttccgcg catcgattaa
    58561 agacgatgca tcgttttctg cgatgggaat agtcata
//
LOCUS       DAPOXO010000021        58532 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPOXO010000021 DAPOXO010000000
VERSION     DAPOXO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 58532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58532
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.021"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(78..293)
                     /locus_tag="ROH59_001621"
     CDS             complement(78..293)
                     /locus_tag="ROH59_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDX4804119.1"
                     /translation="MALNCPTCKTPLERNGETAHCATCDKDFTVQALCPECHQPLQVL
                     KACGAVDYFCQHGHGLISKKRVEFVIA"
     gene            complement(356..1828)
                     /gene="der"
                     /locus_tag="ROH59_001622"
     CDS             complement(356..1828)
                     /gene="der"
                     /locus_tag="ROH59_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDX4804120.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYALGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     SPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK"
     gene            complement(1946..3124)
                     /gene="bamB"
                     /locus_tag="ROH59_001623"
     CDS             complement(1946..3124)
                     /gene="bamB"
                     /locus_tag="ROH59_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HDX4804121.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTVWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVNLAEKDG
                     WFSKDPALLSGGVTVSGGHVYIGTEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            complement(3135..3755)
                     /gene="yfgM"
                     /locus_tag="ROH59_001624"
     CDS             complement(3135..3755)
                     /gene="yfgM"
                     /locus_tag="ROH59_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ancillary SecYEG translocon subunit YfgM"
                     /protein_id="HDX4804122.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDAIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            complement(3773..5047)
                     /gene="hisS"
                     /locus_tag="ROH59_001625"
     CDS             complement(3773..5047)
                     /gene="hisS"
                     /locus_tag="ROH59_001625"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDX4804123.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQVL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            complement(5158..6276)
                     /gene="ispG"
                     /locus_tag="ROH59_001626"
                     /gene_synonym="gcpE"
     CDS             complement(5158..6276)
                     /gene="ispG"
                     /locus_tag="ROH59_001626"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDX4804124.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            complement(6303..7310)
                     /gene="rodZ"
                     /locus_tag="ROH59_001627"
     CDS             complement(6303..7310)
                     /gene="rodZ"
                     /locus_tag="ROH59_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HDX4804125.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELNNNQSQ
                     SVPLDTSTTTDQAMATTPTSPVDTTATNTQTPAVTAPAPAVDPQQNAVVPPSQANVDT
                     AATPAPAATTTPDGAAPLPTDQAGVTTPAVDPNALVMNFTSDCWLEVTDATGKKLFSG
                     MQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPA
                     Q"
     gene            complement(7595..8749)
                     /gene="trmG/rlmN"
                     /locus_tag="ROH59_001628"
     CDS             complement(7595..8749)
                     /gene="trmG/rlmN"
                     /locus_tag="ROH59_001628"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HDX4804126.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            complement(8899..9330)
                     /gene="ndk"
                     /locus_tag="ROH59_001629"
     CDS             complement(8899..9330)
                     /gene="ndk"
                     /locus_tag="ROH59_001629"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDX4804127.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            complement(9479..11791)
                     /gene="pbpC"
                     /locus_tag="ROH59_001630"
     CDS             complement(9479..11791)
                     /gene="pbpC"
                     /locus_tag="ROH59_001630"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HDX4804128.1"
                     /translation="MPRLLTKRGCWIMLTAAPFIIILAAWAADKLWPLPLQEVNPARV
                     VVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAA
                     RNKVLERMAVQGVWSRERVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMV
                     NAIRSPGSVLKPFAYGLALDEGVIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAQPLPDGALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSVNLPEDPRPDSVSRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPEQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTICP
                     PYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDDVGQIATVKFVMQ"
     gene            complement(11792..16753)
                     /gene="yfhM"
                     /locus_tag="ROH59_001631"
     CDS             complement(11792..16753)
                     /gene="yfhM"
                     /locus_tag="ROH59_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HDX4804129.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     VSSAKLSAPERQKLAQQSAGKALTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDDEKTIT
                     TRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAALQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKNGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPDQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSV
                     VGYYLYGALANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASK
                     SVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     YEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGGGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVPAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPTKMRPNQPLTVKIKASNKNGEMPKQVNVLVSAVDSGVLNITDYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVAQQA
                     LPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSNSPAPVELAPGVRTTLFIPVR
                     ALTGYGDGDIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAL
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDAINRGNERLLRYLQDPGMISIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKIMGDATRGEEAIVLALKTPRNSDERIW
                     LGDYGSPLRDSALMLSLLEENKLLPDEQYSLLNTLSQQAFGERWLSTQESNALFLAAR
                     TLQDLPGKWQAQTTFSAEPLTGEKAQTSNLNSDQLATLQVTNSGDQPLWLRVDASGYP
                     QSAPLPASNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLP
                     AGLELENQNLANGGASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPV
                     TLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAADDLLIVRP"
     gene            16960..17805
                     /gene="sseA"
                     /locus_tag="ROH59_001632"
     CDS             16960..17805
                     /gene="sseA"
                     /locus_tag="ROH59_001632"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HDX4804130.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWLRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDV
                     LLASHENTAQIIDARPATRFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPVK"
     gene            complement(18298..19074)
                     /gene="sseB"
                     /locus_tag="ROH59_001633"
     CDS             complement(18298..19074)
                     /gene="sseB"
                     /locus_tag="ROH59_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HDX4804131.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGEEGNPLSSQEVLEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKPVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQVAGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIAPFYERRWGGFLRDFKQNRII"
     gene            complement(19216..20499)
                     /gene="pepB"
                     /locus_tag="ROH59_001634"
     CDS             complement(19216..20499)
                     /gene="pepB"
                     /locus_tag="ROH59_001634"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HDX4804132.1"
                     /translation="MTEAMKITLSTQPADVRWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKVDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPELDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLICNVAGDRVTYRITKGEDLREQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     ASQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA"
     gene            complement(20558..20758)
                     /gene="iscX"
                     /locus_tag="ROH59_001635"
     CDS             complement(20558..20758)
                     /gene="iscX"
                     /locus_tag="ROH59_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HDX4804133.1"
                     /translation="MGLKWTDSREIGEALYDAYPDIDPKTVRFTDMHQWICALEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            complement(20770..21105)
                     /gene="fdx"
                     /locus_tag="ROH59_001636"
     CDS             complement(20770..21105)
                     /gene="fdx"
                     /locus_tag="ROH59_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HDX4804134.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDVALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            complement(21107..22957)
                     /gene="hscA"
                     /locus_tag="ROH59_001637"
     CDS             complement(21107..22957)
                     /gene="hscA"
                     /locus_tag="ROH59_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HDX4804135.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            complement(22974..23489)
                     /gene="hscB"
                     /locus_tag="ROH59_001638"
     CDS             complement(22974..23489)
                     /gene="hscB"
                     /locus_tag="ROH59_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HDX4804136.1"
                     /translation="MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            complement(23585..23908)
                     /gene="iscA"
                     /locus_tag="ROH59_001639"
     CDS             complement(23585..23908)
                     /gene="iscA"
                     /locus_tag="ROH59_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HDX4804137.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            complement(23925..24311)
                     /gene="iscU"
                     /locus_tag="ROH59_001640"
     CDS             complement(23925..24311)
                     /gene="iscU"
                     /locus_tag="ROH59_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HDX4804138.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            complement(24339..25553)
                     /gene="iscS"
                     /locus_tag="ROH59_001641"
     CDS             complement(24339..25553)
                     /gene="iscS"
                     /locus_tag="ROH59_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDX4804139.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            complement(25665..26153)
                     /gene="iscR"
                     /locus_tag="ROH59_001642"
     CDS             complement(25665..26153)
                     /gene="iscR"
                     /locus_tag="ROH59_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HDX4804140.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKL
                     RA"
     gene            complement(26424..27164)
                     /gene="trmJ"
                     /locus_tag="ROH59_001643"
     CDS             complement(26424..27164)
                     /gene="trmJ"
                     /locus_tag="ROH59_001643"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HDX4804141.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKAE"
     gene            27283..28086
                     /gene="suhB"
                     /locus_tag="ROH59_001644"
     CDS             27283..28086
                     /gene="suhB"
                     /locus_tag="ROH59_001644"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HDX4804142.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            28231..29085
                     /locus_tag="ROH59_001645"
     CDS             28231..29085
                     /locus_tag="ROH59_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417029.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4804143.1"
                     /translation="MALPVNKRVLKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSLAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILDVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            29276..30556
                     /gene="csiE"
                     /locus_tag="ROH59_001646"
     CDS             29276..30556
                     /gene="csiE"
                     /locus_tag="ROH59_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HDX4804144.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATTATFSELNGVDD
                     DIASLDISETGREILRYHQLTLTTGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSRFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFETRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKAFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(30548..31687)
                     /locus_tag="ROH59_001647"
     CDS             complement(30548..31687)
                     /locus_tag="ROH59_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HDX4804145.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVSMFDYRVIL
                     ALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAIC
                     GVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            32057..32479
                     /locus_tag="ROH59_001648"
     CDS             32057..32479
                     /locus_tag="ROH59_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311436.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDX4804146.1"
                     /translation="MNSLRYFDFGTARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQ
                     YMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAVIGHHYWDM
                     TGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR"
     gene            complement(32527..33399)
                     /locus_tag="ROH59_001649"
     CDS             complement(32527..33399)
                     /locus_tag="ROH59_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HDX4804147.1"
                     /translation="MTIYTLSHGPLKLDVSDQGGVIEGFWRDTTPLLRPGKKSGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSRSDDSLC
                     LVYEHLSGVYHYRVSQAFHLTADTLTVTLAVTNQGAETLPFGTGWHPYFPLSPQTRIQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFNQLAPLPRQWVNNGFAGWNGKARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTISEMSLRVALL"
     gene            complement(33411..34505)
                     /locus_tag="ROH59_001650"
     CDS             complement(33411..34505)
                     /locus_tag="ROH59_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDX4804148.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGEGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            complement(34538..35536)
                     /locus_tag="ROH59_001651"
     CDS             complement(34538..35536)
                     /locus_tag="ROH59_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804149.1"
                     /translation="MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEV
                     PLAIACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPIN
                     ENEVLDWLGGQFLGVPVSALIMMVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRG
                     SLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            complement(35539..37068)
                     /locus_tag="ROH59_001652"
     CDS             complement(35539..37068)
                     /locus_tag="ROH59_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDX4804150.1"
                     /translation="MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLKKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIMDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLETYEQGEIVINGEKIMRPDYGDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHSPVNVDELMSAILSTDEFYRG
                     T"
     gene            complement(37091..38074)
                     /locus_tag="ROH59_001653"
     CDS             complement(37091..38074)
                     /locus_tag="ROH59_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDX4804151.1"
                     /translation="MPKKMTRTRNLLLMATLLGSALFARASDKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
                     QPKIAVINCEAFEVCVQRRKGFEEVLKTRVPGAQIVANQEGTVLDKAISVGEKLIIST
                     PDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVFTQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            complement(38171..41452)
                     /locus_tag="ROH59_001654"
     CDS             complement(38171..41452)
                     /locus_tag="ROH59_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HDX4804152.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHDDGAQTVWVGETESMHGLQVMT
                     GFTLRPDRAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCN
                     ALLDDAVALTPATAIQGVLHGINPERLTIELSDADGNIVLSYHEHQPQALPLPDVAKA
                     PLAAQDITSTDEAWFIGQHLEQYHHASRSPFDYYLRGVALDPLDYRCNLALAMLEYNR
                     ADFPQAVVYASQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGNFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARL
                     QREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPAL
                     AADMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDAFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYGKAIALWQRCVEMSPEFADGWRGLAIHAWNKQHDYELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGVTPEKRLARLEDNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQHLDDREPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAVCANAQGDETEATRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQQTAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLAAAGLGEVAHYESARAELMAINPAWPKAALFTTVMPFI
                     FSYVH"
     gene            41570..42763
                     /locus_tag="ROH59_001655"
     CDS             41570..42763
                     /locus_tag="ROH59_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDX4804153.1"
                     /translation="MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
                     MPQAPWATPIEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQVRDFCVINVDYGIG
                     SSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLNPEKLTTAQLIAAWQSGEPWFTSWVDHSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            complement(42827..44080)
                     /gene="glyA"
                     /locus_tag="ROH59_001656"
     CDS             complement(42827..44080)
                     /gene="glyA"
                     /locus_tag="ROH59_001656"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDX4804154.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            44409..45599
                     /gene="hmpA"
                     /locus_tag="ROH59_001657"
     CDS             44409..45599
                     /gene="hmpA"
                     /locus_tag="ROH59_001657"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HDX4804155.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAVAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            complement(45644..45982)
                     /gene="glnB"
                     /locus_tag="ROH59_001658"
     CDS             complement(45644..45982)
                     /gene="glnB"
                     /locus_tag="ROH59_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HDX4804156.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(46043..47377)
                     /gene="glrR"
                     /locus_tag="ROH59_001659"
     CDS             complement(46043..47377)
                     /gene="glrR"
                     /locus_tag="ROH59_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HDX4804157.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRNELDANDFKE"
     gene            complement(47367..48080)
                     /gene="qseG"
                     /locus_tag="ROH59_001660"
     CDS             complement(47367..48080)
                     /gene="qseG"
                     /locus_tag="ROH59_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HDX4804158.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQSHNRPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGNWQ
                     NTFKQGILLADAKITPYERRQLVARIDALSTEIPAQVRPLYQLWRDGQALQLQLAEER
                     QRYSKLQQSSDSELDTLRQQHHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHESEKPAPSTDEVTPDEP"
     gene            complement(48245..49672)
                     /gene="qseE"
                     /locus_tag="ROH59_001661"
     CDS             complement(48245..49672)
                     /gene="qseE"
                     /locus_tag="ROH59_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HDX4804159.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETL
                     VSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSL
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
     gene            complement(50248..54135)
                     /gene="purL"
                     /locus_tag="ROH59_001662"
                     /gene_synonym="purI"
     CDS             complement(50248..54135)
                     /gene="purL"
                     /locus_tag="ROH59_001662"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDX4804160.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGMAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
                     VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWIIDGEQQPKSLFKMIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKDEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDADIASLGD
                     DRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVSGDRFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APFIATGVRPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTGLEGFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            54393..55949
                     /gene="mltF"
                     /locus_tag="ROH59_001663"
     CDS             54393..55949
                     /gene="mltF"
                     /locus_tag="ROH59_001663"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HDX4804161.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKDTKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            complement(55946..56482)
                     /gene="tadA"
                     /locus_tag="ROH59_001664"
     CDS             complement(55946..56482)
                     /gene="tadA"
                     /locus_tag="ROH59_001664"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDX4804162.1"
                     /translation="MRRAFITGVFFLSEVEFSYEYWMRHAMTLAKRAWDEREVPVGAV
                     LVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCA
                     GAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFF
                     RMRRQEIKAQKKAQSSTD"
     gene            complement(56507..57142)
                     /gene="yfhb"
                     /locus_tag="ROH59_001665"
     CDS             complement(56507..57142)
                     /gene="yfhb"
                     /locus_tag="ROH59_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311453.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HDX4804163.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHNEARLQALQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE"
     gene            57351..58199
                     /locus_tag="ROH59_001666"
     CDS             57351..58199
                     /locus_tag="ROH59_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDX4804164.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRHSEA
                     LVKKLV"
     gene            58255..58515
                     /gene="yfhL"
                     /locus_tag="ROH59_001667"
     CDS             58255..58515
                     /gene="yfhL"
                     /locus_tag="ROH59_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster ferredoxin YfhL"
                     /protein_id="HDX4804165.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGEHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPQHVETEEQLWDKFVLMHHADKI"
BASE COUNT        13846 a        16311 c        14573 g        13802 t
ORIGIN      
        1 tagttattcc accataacag attgttttat catttgcaca ttaaatacaa atgacaaaac
       61 aatacattca agtgatatta agcaataaca aattcaacgc gttttttaga tattaaaccg
      121 tgcccatgtt ggcagaaata atccacagca ccacaagctt ttaacacttg taacggctga
      181 tgacactcag ggcaaagtgc ctggacggta aagtctttgt cgcaagttgc acagtgagca
      241 gtctcgccat tgcgttcgag aggggttttg caggttggac agttgagtgc cataaatact
      301 cctcgcgtgt tattcggttt ccctctccgt gtggaaaggg aaaccagata agtgattact
      361 tacttttctt gatgtgcttc atcagacgct tacgcttgcg catctgagtc ggcgtcaggg
      421 tattacgctt gttcgcatac gggttttccc cttctttgaa ctgaatacga atcggcgatc
      481 ccattacgtc cagggatttg cggaagtagt tcatcaggta acgcttgtag gaatcaggca
      541 ggtctttcac ctgattgccg tgaatcacca caatcggcgg gttataaccc ccggcgtggg
      601 cgtatttcag cttcacacga cgaccgcgta ccagcggcgg ttggtgatct tcaacagcca
      661 tcgtcatgat gcgcgtcagc atagaggtcc ccacacgacg ggtggagctg tcatacgctt
      721 cacgtactga ttcaaacaag tttccaacac cactgccgtg caaggcagag ataaagtgca
      781 cacgagcaaa atcgataaag cccagacgga agtccagcgt ctctttcacc tgctctttca
      841 cttcctggct caggccgtcc cacttgttca ctacaatcac aagtgagcgc ccactattga
      901 gaataaagcc cagcaaggag agatcctgat cggaaatacc ttcgcgcgca tcaatcacca
      961 acatcaccac gttggcatct tcaatggcct gcaacgtttt gattaccgag aatttctcta
     1021 ccgcatcggt gattttgccg cgtttacgta cgccagcggt gtcaatgagc acatactcac
     1081 gtccgtcgcg ttccattgga atgtagatac tgtcacgcgt cgtgccaggc atgtcgtaaa
     1141 caacaacgcg ctcttcacca agaatacggt tagtgagtgt agacttacct acgttcgggc
     1201 gacccacaat cgccagtttg atcggcagac tttgcgggtc gaagtcgtct tcctcttctt
     1261 cttcgccgtt ctcttccgct tcaaattgcg cccagtattc ggcgtcttcg tcgacttctt
     1321 cttgcggtgc gagatcttcc atccacggca gcagcacgtg ctccagcaga cttaatacgc
     1381 cacgaccgtg agacgcggcg atcgggtaga tttcacctaa accaagcgcg tagaaatcaa
     1441 ccactgcctg atcgggatcc agaccgtcag ttttgtttgc caccaggaag gtcggttttt
     1501 cacgggagcg cagatgttta gcaatcgctt catccgccgg catcaggccc gcgcgcgcat
     1561 ccaccataaa cagtacgacg tccgcttctt caatcgccag cagcgactgt tccgccatgc
     1621 gggtttctac accgtcttct gtgccatcaa tcccgccggt atcaatgcag ataaactcac
     1681 ggccttcaat ttccgcacga ccgtacttac ggtcacgagt cagacccggg aaatccgcaa
     1741 ccagcgcatc tcgggtgcga gttagacggt taaataacgt ggattttcct acgttagggc
     1801 gcccgacaag cgcgaccaca ggtaccatgt ttaaagcctc atttttataa atcatcagac
     1861 aacgcacgct atattcgtgt cgttgttaaa aacaggaaaa cggcccctgt ccaggagccg
     1921 ttttcaaagt gaacgacaga gacgattaac gtgtaataga gtacacggtt ccgtcttttg
     1981 cctggatcag cagtttgccg tcagcagcaa ccggttcagt ctggaaaccg gaactatcaa
     2041 ctttttgctg ggcaacgaaa cgaccatctt cgacgttaat ccagtgcaga taaccttcac
     2101 tgtcgcctac caccaggttg ccattataca gcaccggaga agtcagcagg cgatgcagca
     2161 gatcgctttg tgtccacagc gtaacgccgc catcaatggt caacgccatc acccggtcat
     2221 tttgatcgac cagatagatg cgattgccgt cgacgatgaa atcattcacc gaacccagtt
     2281 cgcgtttcca cataatctga ccactgcgca gatcaagcgc cgtcaggtta ccattatagg
     2341 ccagcgcgaa aacaacgccg ttaacaacga cgggagtcgt gtcaacatcg ctcagacggt
     2401 caatttcggt agaaccggtc gcctgggaaa tacgctgctg ccaaatcatc tggccctgtt
     2461 ccatcagcac tgcgctgacg cgaccattat cgccacccac gacggccgca ccaaaagccg
     2521 ttgccggcgc agactcgcca cgcaaagaga gcgaaggcat atcgaggtta actgtccatt
     2581 tgacagcgcc gtcagcttcg ttcagcgctt gtaactgacc gttactggtg tggattaaca
     2641 ccagaccgtc gctgaccacc gggcgcgaaa gtgcttcacc cgcgacttta gtttgccatg
     2701 ccacagtacc atcgctggta ttcagcgcgt aaacctgcgc cttttcggtg ccaatgtaga
     2761 catgcccacc agacacggtc acgccgccag aaagtaatgc aggatcttta gagaaccagc
     2821 catctttctc ggccaggttg acagaccaga tttctttgcc gtcatccgca ttcagcgctt
     2881 ttactaaacc agcgcggtcc gctgcataga caacgttgtc cgccagtgcc ggatgaagat
     2941 tggaatagaa gttgccaatg ccgctaccaa cggaagtgct ccacacagta gtcggcgtaa
     3001 actggttttc aacggttggc aatggggaca tctttaccac atcttcttcg ctgttaaaca
     3061 gcgaacagcc gcttaaaagg gtaacggaaa gcagtcctgg cagcagtaat ttacgcaatt
     3121 gcatcgggtc cctctcagat ggacaaatta ttaattttca tctgcatcat ttcgctcagt
     3181 gccggggtaa catcgctttt cacgcctgct tcccatgcac tacgcgcacc ttgcttatca
     3241 cctttgctca gcaatgcttc accacgcagg tcggcaacaa tggcagccca cccttcacct
     3301 ttgatagcat caagggtttt tagcgcggca tcagcctgct tgagctgtac ctgaacgcga
     3361 gcaagacgca gatttatcac ggctttgaga ttttcatcgc tcgtgtctgc cagcccctgt
     3421 tgtaactggg cggcagcttt ctctagttca tttttgtcaa caaattgctg cgcaagttcc
     3481 aaagaagcca gcgcaccata agtattttta ttttcagcag caaatttttc cgccgctggg
     3541 atgctatccg gtttgccttc gctcactgcg gtaaccgcat tttgataggc aagagaagcg
     3601 gagcgtgcag aatcaacctg atggctattc cagtagcgcc agccaatcag tgcgccaacg
     3661 cccaaaatca ccccaacagc cagtgctttg ccattttcag caaaaaagcg tttaaccgct
     3721 tcaacctggt cgttttcgtt ctcgtaaatt tccacgctgt ccttctcctt ccttaaccca
     3781 gtaacgtgcg caaatgcgcg gctacgctat cctgcgcaac tgcagtttgc tcaccagagc
     3841 gcaaatcctt cactactgct gtgccgttag ccacttcaga ctcacccagc accacagcaa
     3901 cgcgggcacc ccatttatca gcacgggcaa actgtttctt aaagttgccg ccgccgtggt
     3961 tggtcatcag tttcacaccc ggtaattcat cacgcagacg ctctgctaat gccatagccg
     4021 cagattgtgt gtcagcacct gaagccacca ggtatatatc gacaacagga tcggctttaa
     4081 attccggatt aacggcctga actaacaata caagacgttc gaggcccatc gcaaaaccga
     4141 ctgccggtgt tgcacgacca cccagttgtt ccaccagacc gtcataacga ccacctgcac
     4201 acacggtgcc ctgggaaccg aggctgttag tcacccactc gaaaacggta cggttatagt
     4261 aatccagacc gcgcaccaga cgctggttta cagtgtaagc gatccccgcg ctctcaagca
     4321 gtttgcacag accggcaaag tgctcacgag attcctcgtc cagataatcg cctaatgccg
     4381 gagcgtcgtt gagaagcacc tgcacttccg gattttttga atccagtacg cgcaacgggt
     4441 tagtgtacat gcggcgtttg cagtcttcgt ccagcttttc tttatgctgc tcaaggaatg
     4501 ccaccagcgc atcgcggtaa ttcgcacgag cttccagcga accgatagag ttcagctcaa
     4561 gagttacgtg ctcggaaata cccagcgcgc gccaccagcg ggcagtgagc ataatcagtt
     4621 cggcgtcgat atccggacct tgcagaccga aaacttcgca gcccaactga tggaactgac
     4681 gataacgccc tttctgcgga cgctcgtgac ggaacatagg cccgatatac cacagacgct
     4741 gttcctgatt gtacagaaga ccatgctcga tgccggcgcg tacacagccc gccgtccctt
     4801 cagggcgcag agtcaggctg tcgccattgc gatcctcaaa ggtgtacatc tctttttcaa
     4861 ccacgtcggt gacttcacca atcgcacgtt tgaatagcgg ggtctgctct acaatcggca
     4921 agcggatttc actgtaaccg tagctgccga gcacgttttt cagtgtgcct tcaatgcgct
     4981 gccagatggc cgtttcgcca ggcaggtaat cgttcatgcc gcgaatggct tgaatgtttt
     5041 ttgccacgtt tattctcttt ctgaatataa aaatgaaccc tcaacgcttc cctcaatgtt
     5101 tcgggagcca tgcgggttca atcatacacg ggaagcgagg cgcttcccat cacgttatta
     5161 tttttcaacc tgctgaacgt caattcgacg cgcttcgtcc agctgactgg ctttcgcacg
     5221 aatgcgcgct tccagctgat cgatcatatc gttgttgtcc agacggtctt tgcgcacgcc
     5281 atcttcatag aggccgcttt tcttgttgcc gccagtgacg ccgagtgtag aaaccagcgc
     5341 ctcacctggg ccattcacca cgcagccgat aatcgaaacg tccatcggag tgattatatc
     5401 ttccaggcgt tgctccagcg cgttaaccgt accgataaca tcaaattcct gacgcgaaca
     5461 ggtcgggcag gcgatgaagt tgatcccgcg cgaacggata cgcagcgatt tcaaaatatc
     5521 gaaaccgact ttgatctctt cgaccggatc ggccgccagc gatacgcgca gcgtgtcgcc
     5581 gatgccttca gacagcagca gacctaaacc aatagcggat tttactgccc cgctgcgcgc
     5641 accaccggct tcggtgatcc ccagatgcag cggctgatcg atttgttttg ccagcaaacg
     5701 ataagactca acagcgagga agacgtcaga cgctttcaca ctgactttga actgatcgaa
     5761 gttcaggcga tcgagatgat caacatgacg catggcggat tccagcaacg cctgcggcgt
     5821 cggttcgcca tacttttctt gcagatcttt ttccaacgat ccggcgttaa cgccaatacg
     5881 gatcggaatg tttttatcgc gcgcacagtc aaccaccatg cgaatacgct cttcattacc
     5941 gatattgcca gggttaatac gcagacaatc gacgccgtat tccgctactt tcagcgcaat
     6001 gcgatagtcg aagtggatgt cagccaccag cggcacgtta acctgctgtt tgatgagttt
     6061 gaacgcttct gccgcgtcca tcgtcggtac ggagacacgg acgatatcag cgccaacgcg
     6121 ttccagcgct ttgatttgat tgaccgttgc ttcgacgtct gtcgtacgcg tattggtcat
     6181 ggactgtacg gcgatgggag caccatcgcc aatcggcaca ttcccaacgt aaatacgtgt
     6241 tgattttcta cgttgaattg gagcctggtt atgcatgaaa aatctcccgc gttacccgtc
     6301 tgttactgcg ccggtgattg ttcggcattg agggtcagac gcgcaacctg gttagttctg
     6361 ataaaacgac tcagatcgac aggtttccct tgatactgga tctgtactgc ggctggcgca
     6421 ccaattttca gtttgtacgg tgcctggccg gttaagttca aattaccgtc tttacgctgc
     6481 ataccgctaa acagtttttt accggtagca tcggtgactt ccagccagca atcggaagta
     6541 aagttcatca ccagcgcatt cgggtcaacc gccggcgtgg tcacgccagc ctgatcggtt
     6601 ggcaacggcg cagcgccatc tggtgttgtt gttgccgctg gtgccggagt cgcagcggta
     6661 tcaacatttg cctgcgaagg tggaacaacc gcattctgtt gcggatcaac agctggtgct
     6721 ggcgcagtta cggcaggtgt ttgcgtgttg gttgcggtgg tatccacagg tgatgtcggc
     6781 gtggtcgcca tagcctgatc tgtggttgtc gacgtatcta acggtacact ctggctttga
     6841 ttattattca gttccgcaga agattgatcg gccatagtgg tgatctcttc ctgctgagct
     6901 ttgtggtctt gccaccacca ggcaccgctc agaccaataa ccacaaacaa caccagccag
     6961 gtgaaggtca tcagccagcc gtcacgtttt ttgcggcgtt taccgaggga aaaactctgc
     7021 atcggcgcaa cttttgcagc ccgtagtgga gcctgctttt ccagccctgg cagcagttct
     7081 tcttctggaa tatgtaccag acgcgcataa gagcggatat atccgcgcag gaatgttgaa
     7141 gcaagatcgg cgggtgcctt atcttcttca atgtcgcgta ccgtggaaac cttcaggcaa
     7201 agtcgctcgg caacggcctg ttgactaagt cctagttgtt cgcgagcatt acgcaggcga
     7261 gcgccggtag taagtgcttc attttggtcg tgcgtggctt cagtattcat tcgctgcagg
     7321 tacgtttaaa tgagaattga gatgccggtg aaccatcatg ctcacccaca ccgcgaaaca
     7381 tccgttaagt taaccgttat catacagtat aagaccgtct gtgtgctcgt gacaaagccc
     7441 acattcgcta aggctaactt actgttgcat cgttacatac tgccttaaag tcagcaaaaa
     7501 cgcaccgtta atattgacca gacaattgca acttaatact tcattcataa aagattacgc
     7561 cacggtacat aaagtaaccg tggcgtaatg gctatcagac cgctttaatg tcgatggctt
     7621 caccctgcat ccgtttacgc agggtacgtt tcgtacggtc gataacatcg cccgccaact
     7681 gaccacaggc agcatcaatg tcatcaccac gagttttacg cacaatagtg gtgaaaccgt
     7741 agctcatcag cacttttgag aaacggtcga tacggctgtt cgaactgcgt ccatacggcg
     7801 cgcccgggaa cgggttccac gggatcaggt tgatcttaca cggcgtatct ttcagcagtt
     7861 ctgccagttg gtgcgcgtgt tcagtgccgt cgttaacgtg gtcaagcatc acgtattcaa
     7921 tagtgactcg gccctgattg gcgttggatt tctccagata acggcgcacc gccgcaagga
     7981 acgtttcgat attgtacttt ttgttgatcg gcacaatttc gtcacgaatt tcgtcgttcg
     8041 gcgcgtgcag ggaaattgcc agcgcaacgt cgatcatatc gccgagttta tccagcgccg
     8101 gaaccacacc ggaagtggaa agcgtgacgc gacgttttga caggccaaaa ccgaaatcat
     8161 caagcatgat ttccatcgcc ggaacgacgt tgttcaggtt gagcagcggc tcgcccatac
     8221 ccatcatcac tacgttagtg attgggcgct gaccggtgac ttttgctgcg ccgacaattt
     8281 tcgccgcacg ccacacctgg ccgataattt ccgatacccg caggttgcga ttaaagccct
     8341 gctgggcggt ggaacagaat ttacactcca gcgcacaccc cacctgcgaa gagacgcaga
     8401 gcgtggcacg gtcgtcttcc gggatataca ccgtttcaac gcgctgatcg ccaacggcga
     8461 tcgcccattt aatggtgccg tcagatgaac gctgttcttc aaccacttcc ggtgcacgga
     8521 tttccgccac ctctttcagt ttgccgcgca acactttatt gatgtcggtc atctcatcaa
     8581 agttgtcgca gcaatagtga tacatccact tcatcacctg atcggcgcgg aagggttttt
     8641 cacctaaatc tttaaaaaac tcccgcatct gctgacggtt gagatccagc aggttgattt
     8701 ttccatcttt cgtggtgacg ttttcaggtg tgactaattg ttcagacata tgctattccg
     8761 gcctcgttat tacacgttat ggcccctgga gggttgaaaa aagaaacgcc ccggtgagcg
     8821 gctgctcgtc cgggggcgct gcattgtaca aattctggcg cacggatgcc acgtttgcac
     8881 gcggcattta cgaaattatt aacgggtgcg cgggcacact tcgccttcgc cgaagaaata
     8941 agcgatttcg cgagcggcag attcgacgga atcagaaccg tgggtaccat tttcggtcag
     9001 gctgtcagcg taatcagcac gcagagtacc ggccagcgcg tttgccggat tggtcgcgcc
     9061 cagcagatcg cggtgacgct gaacagcatt ttcaccttcc agcacggaaa caacgatcgg
     9121 gccagaagtc atgaattcaa ccagaccatc aaagaacggt tttccatcgt gttcagcata
     9181 aaagccacga gcctgttcaa cggtcaggtg cagcattttg gtgccgacaa ttttgaaccc
     9241 tgcagcttca aagcgcgcaa agatactacc aatcacgttt tttgctactg cgttcggttt
     9301 gatgatggaa aaagtacgtt caatagccat ttttacctct gtaaattgtt ctgttgttgt
     9361 ctgtaccagc gtacgagatg gcgcggatta taatgagcaa cagggccgtt gactattgat
     9421 gaaggtaaca tttttttaaa ataaacccag tttaagcaac aatcagggac aaaacagact
     9481 attgcatgac aaatttcact gtcgctattt gccccacgtc atccatcacc agcaattgat
     9541 aatcgccttt atccgtcaaa tgcagggtca cgttgcgccc acgttcagtt aacggttcgc
     9601 cgttcagaaa ccaccagcgt tcacctgccc ctccacttga ttgcaacggc aaagtcgctt
     9661 ccgctgcgcc cggtaaacgt ttaataatcg cgccatcgcg cacacctgtt agctgcagcg
     9721 ggagttgtgc atcgtgaccg tatggcgggc aaattgtcga ggccggaggc aagcgcacag
     9781 cgcgacgttc tgatgcgggc agccagggtt ccagcggtag cggccagaca tttatcattt
     9841 cttgtcgcgc ctgagggcaa tcagcggcaa cacgtttgcc gttttcatcc agccagatgg
     9901 ggaaacgaat gccattaatg ccttcctgct ccggcagtaa tagagttggc ggctggctcc
     9961 cgtccagcag ccaggttgcc aggcggcggc gacagttacc gtcaccttcc ggcaaagact
    10021 gtccgcccgg ccagcagata acgccacgac ttacagagtc aggacgtggg tcttccggca
    10081 aattcacact gcgcgacagt aagatattat taacctgatt caacagcggt acggcactgg
    10141 caaagccaaa ctgaccaaca acgggcgtgc cgtccggtct gccagtccag atcccaatga
    10201 catagcgagc gttaacccca atcgcccagg catcacgata gccatagctg gtgcccgttt
    10261 tccatgccag tggggcgacg cgcggcaagg caccatccgg caagggttgc gcttcatcag
    10321 ccataatccg gcgaatgatc cacgcagccc ccgacgacat taaaggccgt tcaagcagcg
    10381 gatcgtcagg ctgtaagcgc aatttgcctg ccttgccgtg gcgagcaaac gcggtatacg
    10441 ctgctgccat atcttccagt tttgcgccag cgccgccgag aatgagcgaa agattcggcg
    10501 cagcaccgtt gggcagatac aacggcaatc caacattgcg taactttgcc gcaaaccgtt
    10561 tcggtccata ggcttccagc acctgcacag caggtaagtt cagcgatcgc accagcgcct
    10621 cactcatgct gatcgggcca tgaaaaccgc tgtcaaagtt gccaggtcgg taatcaccgg
    10681 tgcgtcgggg gacgtcttgc aacagcgatg ccgggtggat cacgccttca tccagcgcca
    10741 gaccataagc aaacggtttg agcaccgatc ctggcgatcg gatcgcattg accatatcaa
    10801 catgaccaaa gcgtgaatca tcgttgagat caaccgatcc cacccagccg cgaacacgca
    10861 tatcggtatg atcaaccacg atcatcgcca gtgagctgcg cggtggcaat cgtcctttcc
    10921 agttttgcgc cagttcttcc agacgtcgtt gaagaccggc atccagcgta gtaacgattt
    10981 tgtcgctttt gcttttaccg agcatcatgc gcgaaaacag cggtgccagt tgcggcattt
    11041 gtcggggtgc cagccagatg ggttcttccc ttgactcttt tacccgctca cgggaccaca
    11101 caccttgcac ggccatccgt tcgagcactt tattacgcgc ggcttcggca cgctccggcc
    11161 aacgatccgg gcgaagacgg ctgggcgctt gcggcaacac cgccagcatt gccgcctcgg
    11221 aatagcttaa attcgcaggc gatttcccga gataagccca acttgccgca ccaatcccct
    11281 gcaacgtacc gccaaacggg gcacggttaa gatacaaggt cagaatttca cgtttagaca
    11341 gatgccattc cagttgcaac gcgcgccaga gctgacgaat tttgccgcca aacgttttgg
    11401 ggtgaggatc aagcaggcgc gccacctgca tggtgagcgt gctgccgccg gaaatgaccc
    11461 gacccgacgt gagatcttgc caggctgcac gcgccaccga gaacggattc acccccggat
    11521 gcttccagaa ccagcgatct tcataattga tcagtgcttc aaggtaacgt ggagaaacat
    11581 cttcgattgt taccggataa cgccagatgc cgtcagcatc ggcgaaacgc cagagtggcg
    11641 taccatcctg cgccaccacc acgcgtgcag gattcacttc ttgcaatggc agaggccaga
    11701 gtttatctgc tgcccatgct gccagaatga tgataaaagg cgcggctgtc agcattatcc
    11761 agcagccgcg tttggttaac aggcgaggca tttacggtct gactatcaac agatcgtcag
    11821 ccgcaccagt cgcccgccat tgaggaacat acattgattc caccataggc tgcggcacct
    11881 gatacgttcc cggcgtcacc gcccgcgcca gatacaccag cgttaccggt tgatattcat
    11941 caacggcaac cgccgccaca aagcgatcgt cacggaactc tatgtgctta atgctcgcct
    12001 gctgcatctg gttcagcaag ttctgcactt caccaccact ttgctccagg ctggcgccgc
    12061 cgttcgccag attctggttt tccagttcca gccccgcagg caacagatcc acgactaacg
    12121 catccggtac actgttactg gctttaacct gcaaccacac cagcaccaga tcgccgctac
    12181 gtaacgagtc cagcgatttg ctcttaccgt cagtacccag aatatgacgc tcaatttgca
    12241 gcacattgct cgccggtaaa ggtgcggatt gcggataacc gctggcatcc acacgcagcc
    12301 ataacggctg atcgccactg ttggtcacct gcaaggtggc aagttgatcg ctattcagat
    12361 tgctggtttg cgctttctcg cctgtcagcg gctcagcaga gaaagtggtt tgcgcctgcc
    12421 atttgcccgg taaatcctga agagtacggg cagccaggaa caacgcgtta ctttcctgcg
    12481 tcgatagcca gcgttcaccg aacgcctgct gcgaaagtgt gttcaacagg gagtactgct
    12541 catcgggtag cagtttgttc tcttccagca atgagagcat caacgcgctg tcgcgcagtg
    12601 gactaccgta atcacccagc catatccgct catcactatt acgcggcgtt ttcagcgcca
    12661 gcacaatcgc ttcttcacca cgcgttgcat cacccatgat tttcagcgca acgccaagtt
    12721 gcagcagcgg taaaccagaa gcggcatctg cacgatgctc ccagatttca cgcagcgcac
    12781 ccagtggtgc tttttgctga cgggccaaca ccagcgcagc gtaagactgt acggcgaatt
    12841 tactggcttt gagattatca gcgtacggga tcgatatcat gcccggatct tgtaaatagc
    12901 gcagcagacg ctcattaccc cggttaatgg cgtctgtcgg tacgctgtaa ccctgttcgc
    12961 ctgcgcggac caggaaatcc atcacgtaag ccgtcagcca gtactcttcg tcaccgtttt
    13021 tatcccacag cgcaaagccg ccgttatcac gttgcatttg cagcaaacgg gaaatgccga
    13081 tatcgaccga tgcacggcgt ttctcatcac tgtcgccttt gatgcccaac gcctgcagtt
    13141 gggctgcatt ggtataaagt gacgggaaca ggccgctggc ggtttgctcg agacagccgt
    13201 acggatacgc ttttaactct ttgatataac gtgcgatgtt cagcggtggt ttgccgctca
    13261 acaataactg cccttccagc gtaacaggcg agaagttttg caatccatca gccgggagcg
    13321 cccaggtttc accaggctgt aacgccgtac cgtaattgac cgtttgtgcc gggaatgccg
    13381 gacggacgcc gattttccac tgcttatgct gatcggcaac ggtttccccc ggtaacgcta
    13441 acccgctaat ggtggcctga atgtcaccat cgccataacc cgtcagagca cgcaccggga
    13501 taaacagcgt agtacgcacc cctggcgcta attcaacagg tgcgggggaa ttactcacca
    13561 gttcaagcaa gccactggcg gtcagagcaa cattaagttt ttgcggttta tcggtaagat
    13621 tagtgatatc cagcgtcagg cgcgaggtat cgccactcgc cataaagcgc ggcatgttaa
    13681 gttcagcaat caccggtgcg gcaacaatca ctttgctttc gttgcttccg aagtcatctg
    13741 ccgtccaggc ttgcgccatg acgcgcaatt caccgttaaa atcgccaatt ggcagtgtaa
    13801 ccgagccttc gccctgttca ttgagcgtta ccggcagcgc ctgctgcgcg acaatattga
    13861 cgtgattgac cggcggttta ccaccacgtt tcagctcatc accatcacca ccaaaacgca
    13921 gagctgccag acgcccctga ccttcaataa cctgaccgta aatatcgtaa atgtctgcgc
    13981 catagcgttt ctgaccaaag aacgcctgcc acggatctgg cgtgacgtaa tcagtaatat
    14041 tcagcacacc gctatcaacg gcagacacca gcacattcac ctgttttggc atctcaccat
    14101 ttttattgct ggctttaatt ttcacggtta atggctgatt ggggcgcatt ttggtggggg
    14161 tttccagcgc cagatcgagg cgacggtttt catcaccaag cggcagatgc aacaccccaa
    14221 ccgcgcgttt tggcgtcgcg gagcgagatt tatcgccagg acgtaccacc agcgtactta
    14281 aatacagatc atgacgattc caggttttat cgaccggaat cgtcagatcc agcccttgag
    14341 ccggaacatc aatctcttgc caccacaacg gcccttcact ggactcgacc atcgcataac
    14401 ctttacccgc cgttggcgcg gcaatatgca acttaatggt atcgccaggg cgataactgg
    14461 ctttatccag tttcagcgtg acacggtcgg gtcgcactgc accacccccg tcgctgttat
    14521 cctgccagct ataaccagcc cagaaacgca cactactgac cgcttcattc ggcgctttaa
    14581 cttccagacg ataagcgccc cactctaccg ggaaactgac cttaccggtt tcgtccgctt
    14641 tcagatccag agtttgttca ttttcgatca gatctttttg atcaaactgt gactgccagc
    14701 cttcatattc cgaccagttc cagtagtaat cgcggcgttc gcgaatcagg cgcacctgca
    14761 agcccgacac ggcttttttc acgccttgcg catcgctata aacgatgtca aaagcggcgt
    14821 tactgccttc atcaacaatg ggctgtttca ccgtgctgtc ggtgcgataa tcgtaaaccg
    14881 atttcgaggc gaactgcgga cggatccccg gcaatgcatc ggcaggccag atagcctgct
    14941 cagcacggcg cgtcaccggg cgaccgcccg attccagcaa actaccctgg aaaataacct
    15001 gtaatggaga atgtgtttcc ttccactggc tttctgtaga aacttcgccg cgccctttat
    15061 catccagcgt caactgaact tcatccagcg tgcgggaaag attttcggca gctatatcgc
    15121 cgaattcaaa accaggtaag gctgacacag cttcacgcag tgggcgcagg aaaagttgcc
    15181 cttgcaaagt attaccattc gcaagtgcac catacaggta gtaccccacc acggagaatt
    15241 tcacttcatc tttcggcgtt agcggggttt tctcaccggt cagattcagc gccatacgct
    15301 ctggcataaa atcttcgacg tggaaatccc acatccgata ctggttatcg cccgtgttag
    15361 cgcgaatatg ccacataccg gttgccgcat tgctatcgag tggccaggta aagtggtaga
    15421 ggccattctc cggctgacta acgacgctcc tgagtacctg cccgtcgggt ttaatcacgt
    15481 ctaacttgat gggttgatcg ggcaatgctt taccgtctgc atcacgcagc aaaccattga
    15541 ggatgaccgt ttcacccggg cgataaagat cgcgcgggcc aaacatgaaa aactgtttgc
    15601 tatagcctgg cgcgccagca atgttaaatt ccgctaagtc cagcgccggg agttttaaat
    15661 cgagcagcgt tgtctgaccg tttttacgcg ccagcagtaa tgccgcgttt ttatcatttt
    15721 ccagttgcac atgcccctga gcgtcactgg ttgcctgagt cagagtctgc cctttctcat
    15781 ttaataaaga gacttcaatt ccttgcaggg ccgcgccgtt ttccagactt tgggtaaaga
    15841 tatccagacg attgtgataa cggtgagctg aaacgccaat atcacttaac gtaaacagcg
    15901 tcgcgggatt actgtaatcg taacgtccag cctgattcat cacagccaga tacacgcccg
    15961 cctgctgaag cggtttgata tcgcccagcg gcagcaataa tttttcacgg gtgttacgcg
    16021 caggattgag atcaaaccgt ccggtgtaga ccagatccgc catctgcagc agtttatctg
    16081 actgccagtt cgccagcgaa ttgcggtatt cccactggct aatgaaagcg ggcagtgatt
    16141 ctggtttcac acggaagaag ttaacatcga cattgttaac gttaagcgcc attaccggca
    16201 gcccttcaac gaccttacca ggaagcaacg aaccacgact ggcaaaaccg acgctgggtt
    16261 ggatatcgcg ggtagttata gttttttcgt catctttact aaaggttgcg ttattgagcg
    16321 ctttgacctc cttgccaata gtgacgatca aatcacgttt cggttcgagg tggcgtaaac
    16381 gcagctcttt aagattatct gacagctccc aggcaccatc cactttgccg ctttttttat
    16441 cgacgacatg aataacgcgt gagaaatcct gatccgggtc gagagggatg gagaacgtca
    16501 gcaccagcgt ggctgcgcca tcgagttgaa cttcagagag atccagcaat gtcagcgcct
    16561 taccggcact ctgttgggcc agtttttgtc gctccggcgc ggaaagtttt gctgaactca
    16621 cgttttctga agaggccgct ttagtaactt cagaaggcgc atcttttttc accgctgttg
    16681 gcgcgttatc gttgttgtcg caccctgcca gcgccagcat tagcatgcag gcggctacgc
    16741 gtaacttttt catttttcat ccctgccaca atggcccgtt agcaacgtcg aataattatt
    16801 atgcgtgaga atttacgtta tgtaattcag tatcacgccc atacaatccg aattttagtg
    16861 agaattgtgg ctcagacagc caaatcagcc tcttttgctt gtcgcttttc actaaacatc
    16921 cgacaattta gcctaacccc ggcaaaaatg gagatgccta tgtccacgac atggtttgta
    16981 ggagccgact ggctcgccga acatattgat gacccggaaa ttcagattat cgatgcccgc
    17041 atggcgtcgc ctggacagga agatcgtaac gttgctcagg agtatctgaa tggacatatt
    17101 cccggcgcag tgttttttga tatcgaagcg ctttctgatc acacttcccc gcttccgcac
    17161 atgctgccgc gcccggaaac gttcgccgtg gcgatgcgtg aattaggcgt taaccaggat
    17221 aagcacctga ttgtctatga cgaaggtaat cttttctcag ccccacgagc atggtggatg
    17281 ctgcgcacct ttggtgtaga gaaagtgtcg attctgggtg gtggacttgc aggctggctg
    17341 cgtgatgatc tgctattaga agaaggcgca gtagagctgc cggaaggaga gtttaacgcc
    17401 gcgtttaatc ctgaagccgt ggtgaaagta accgatgtat tattggcaag ccatgaaaat
    17461 acggcgcaaa ttattgatgc ccgcccggct acacgtttta acgcagaagt tgatgaacct
    17521 cgcccaggtt tacgtcgcgg acatattccc ggtgcattga acgttccgtg gacggaactg
    17581 gtacgtgaag gcgaactaaa aacgaccgat gaactggatg cgatattttt tggtcgcggt
    17641 gtcagctatg acaaaccaat tatcgtcagc tgcggttctg gtgtaacagc agccgtggtt
    17701 ttgttggcac ttgcgacgtt ggatgtgcca aacgtgaaac tgtacgacgg cgcatggagt
    17761 gaatggggcg cacgggcaga tttaccggtt gagcccgtaa aataagcttt ttacgggcaa
    17821 taaaaaaccg ccgaatttgg cggtttttta ttgctggtct ggttcgcggc ctttccagca
    17881 ggttgtatta ccgtagtaat gcaagcgcgt ctcagcggac acaatactcg ccagtaactc
    17941 tctttttgtc aagtaaaaga gagttattat tgttctgtta gtgtattatc cactgcggcc
    18001 ctttccgccg tctcgcaagc gggcgctggc ttaaggaaag gatgttccgc gaccgttagg
    18061 gcaagcgcgt ctcagcgctt gctatcgcgg caatatcgcc agtggtgctg tcgtgatgcg
    18121 gtcttcgcat ggaccgcaca atgaagatac ggtgcttttg tatcgtactt attgtttctg
    18181 gtgcgctgtt aaccgaggta aataataacc gaagtctctt cggcgacaat ttactggtgg
    18241 ttaacaacct tcagagcagc aagtaagccc gaatgccgcc ctttggggcg gcatatttta
    18301 gattatccgg ttctgtttaa agtcacgcaa aaaaccaccc cagcgacgtt catagaatgg
    18361 cgcaatatgt tcggtaataa agtggctaat tcctttttcc ccttttttca cctgacaaat
    18421 atcgatgggt tcatcaccag gtaatgtatc ggtcgctaca cttcccgcca cctgaataat
    18481 ttcttcgata tcaccatcgg cttcaatgcc aataagtaaa ttaggctgtg cctcttcgtt
    18541 ctctttaatt gaacaaataa aagcacgctt caccggctta atggttttaa ataaggtggt
    18601 aagtgaatca atcatttgcg ctggcggctc tgcgacttcc gataatatca gcgattcacc
    18661 gccttccagt acttcctggc tactcagcgg attcccttct tcaccaatca acaaactgat
    18721 ttcacgcggc ataaactctt taccggttgg cagtttggca ttaaggaaga gcgtttcgcc
    18781 aagggtcatc tcaaacaatg tgcgaacggg cattacgaca aatgcctgtt cgtcttcaac
    18841 cgcctgttga agtgcttcta acgaggtaaa aaaaggaatg acgctggtgc cgtcttcttt
    18901 ttcccagtgc tgtaaatcaa gcgcgctatc ttcaactact gcctcgccct gcgccgccgt
    18961 accaggcacc cagacggtgg attccagtag agtacggaaa aaggccgggc ggtgcgccgg
    19021 ttcggttgct gctttttcca gcaggtcttc aagttcgttt tttgtttcgg acataagaac
    19081 cacaattcat tcaacgttcg gggagcaagt gcctgatgcg ccacgcttat caggcctaca
    19141 agggagtcgc aatctattgg attttcgcaa tttgtaggcc ggataaggcg tttacgccgc
    19201 atccggcata ttagtttacg ccgttaacag attagcaatc gtgcgcacac caagtcccgt
    19261 agcacccgca gaccactgtt caaccggcgc tttacggtaa gtcgccgagc agtcgatatg
    19321 cagccagcct tgctgatagt tctcaacaaa gtgcgacagg aagcccgcag ccgtacttgc
    19381 acctgccgga tacgccgcgc ttccggtatt gttcagttcg gcaaagttag acggcagctg
    19441 gctgcggtgg aattccgcca gcggcagacg ccagaacggt tcgttctctt gtgaggcact
    19501 cgccagcaaa cgaccggcaa gcgcatcgtc aaaactgaac aacgcgtgat aatcattacc
    19561 cagcgcagtt ttcgccgccc cggtgagggt cgccgcatca atgatcagtt ccggtttctg
    19621 cgcactggca tcaatcaggc catcggccag caccagacgc ccttcggcat cagtgttcat
    19681 cacttcaact tttttaccgt tgcgataggt gatgatatcg cccagcttga acgcattgcc
    19741 gctgatcagg ttatccgcac aacagaggaa cagcttcacg cgcttgttca gtccgcgcgt
    19801 aatggcaaat gccagcgccc cggtaaccgt tgccgcaccg cccatatccg acttcatcga
    19861 gtccataaac gcggtctgtt tgatgctgta gccgccggaa tcaaaagtga tgcctttacc
    19921 aaccaggcac gcgtacactg gcgcttcttt atcgccagtt gggttgtaat ccagcgccag
    19981 caataccgga gaacgttctg aaccgcgccc gacagtgtgc agccccatat aaccttgctc
    20041 acgcagatct tcgcctttgg tgatccggta agtcacacga tcccctgcga cgttgcagat
    20101 cagatcaaca gcacgctgtg ccagttgcga tggtcccagc tcttctgccg gtgcgttgat
    20161 ggtgtcacgc acccagtcaa tgatcatcag gcggttatcc agttcctgac gctgggcatc
    20221 gtccagctct ggccactcca ctttacgtgt gcctttcggg gctttgtaac cttgccagaa
    20281 tgcccagcag cgatccgcat cccagccttc accgcttaac tgaacatgct taatgcccag
    20341 accatcaacc ttgcgcgccg cacgctggat caaccccaga tcgtctgccc cgttcaaatg
    20401 cagggtaatg ccatcattat taatgctgta agttgctttt tctccccagc gcacgtcggc
    20461 aggttgggta gaaagggtaa ttttcatcgc ttctgtcatt ttagttatcc ttattcgttt
    20521 aacagcaaaa cgggctaccc ccaggcagcc cgttcattca ctcggcttcg tccagccaga
    20581 ccaacaaaat cgcttcgagg attttctcgt tcgatgcctg cgggtcgtcg tcgaaatctt
    20641 ccagagcgca aatccactga tgcatatcgg tgaatcgaac cgttttcgga tcaatatcgg
    20701 gatacgcatc gtacagtgct tcgccaattt cgcggctatc ggtccactta agtcccatac
    20761 taacctctgt taatgctcac gcgcatggtt gatagtgtaa cgcgggattt cgaccactaa
    20821 atcttcgtcg gtaacgcgcg cctggcagct taaacggctt tccggctcca gcccccaggc
    20881 tttgtccagc atgtcgtctt cctgctctga gctttccggc agcgagtcaa aaccttcgcg
    20941 aacgatgcag tggcaggtgg tgcaagcaca ggatttttca caggcgtgtt caatctcgat
    21001 accgttacgc agcgcaacat cgagaatggt ttcaccgcta ttcgcttcca gaacagcgcc
    21061 atcagggcag agatcctgat gaggcaaaat aacaatcttt ggcatattaa acctcgtcca
    21121 cggaatggcc tttcagcgca cgacgaaccg actggtccat gcggcgagcg gcgaaatcct
    21181 gggtttgttt gtctacgttt ttaatcgctt gttcgatggc gtcaacatca tcgccctgcg
    21241 ccacttcact caggtgagcg gcagcatcgt cgataacctg acgttctgcg gcgcttaaca
    21301 gcgcggcatc agcagccagc gcaccgtgca gactttccag cacacgcgcc gcttctactt
    21361 tttgttctgc cagcattcgg gcttttacgt cctgctcggc atagctcatt gagtctttga
    21421 tcatcgaggc gatttcgcta tcggtcaggc cataagacgg tttgacctga atagacgcct
    21481 caacgccggt ggatttctcc atcgccgtca cgctcaaaag accgtcggca tcgacctgga
    21541 acgtcacgcg aatatgcgca ccgccagccg gtagcgccgg aatacctcgc agcgcaaaac
    21601 gcgccagcga gcggcagtcc tgcaccagtt cgcgctcacc ctgcatcaca tggatagaca
    21661 tcgccgtctg accatcttta aaggtggtga aatcctgggc gcgggccacc ggaatcgtgg
    21721 tattacgcgg gatcactttc tccaccaggc cgcccatcgt ttcgaggccc agcgacagcg
    21781 ggatcacatc cagcaacagc atttcgctgt ccggcttgtt acccaccaga atatccgcct
    21841 gaatcgccgc gccaatagcg acgactttat ccgggtcgat agaagtcagc ggtggacgac
    21901 cgaaaaattc gcctactcgt tcacgcacca gcggcacgcg agtagaaccg cccaccatca
    21961 ccacttccag cacttcatca gcttctacgc ccgcatcttt cagcgcgcga cgacaagcca
    22021 gtaaggttcg ttttaccagt ggcgcgatca gttcattgaa ttgttcacgg ctgatttcgc
    22081 cctgccagcc cgcaacgtta acggtcacag agtccgcatc gctcagcgcg attttggccg
    22141 caatggcagc atcgagcagt tcacgctgaa cgcggttatc gctacgatca ggaatgcccg
    22201 cctgctcgcg aatgtaatcc gccagcagat ggtcgaaatc atcgccgccg agcgcggaat
    22261 caccgccggt cgccagcact tcaaacacgc cgcgacttaa gcgcagaatg gaaatatcaa
    22321 acgtcccgcc gccgaggtca taaacagcga tcacgccttc ctggccggaa tccagcccgt
    22381 aggcaatagc cgcagcggtc ggttcattaa gtaagcgcag aacatgcagc cccgccagac
    22441 gcgccgcgtc tttggtgccc tgacgctggg catcatcaaa gtacgccgga acggtgataa
    22501 cgacaccatc cagctcgcct gccagggctt cagttgcccg cgccgccagt gctttgagga
    22561 tgtccgcaga aacgcgcacc gggttcagca gccccgccgc cgtttcaatc atcggcaggc
    22621 cattctcgct ggcctggaat tgataaggca gatgcggata gcgttgctgg atatcagcca
    22681 gcgagcgccc catcaggcgt ttaacagaac taatggtgtt ggcggtgtcg agcgctgcgt
    22741 tagtacgcgc gtcataaccc accgaatgcc cttgctgttg atagtgaaca acagacggca
    22801 gcaggtgacg gccttcatgg tcagctaacg tttcggcctg accgctgcgc actgttgcca
    22861 ccagcgagtt ggttgtgccc aggtcaatac cggccgccag gcgacgctga tgcggcgcag
    22921 cactcaaacc aggttcacta atttgtaata aggccatgtt tagcttccag aaattaaaaa
    22981 tcgagcagtt tttcttcgag ttgttcggca ctgctccgca gtttatcgag aaaacgcagc
    23041 ttacgcacag tatccgccgc cgcgtcccac gtctcgttgt ctaactgttc aaccatcaac
    23101 tgatggcggg tatcaaacat ctttttcaca cgtttgataa agctttccag ccgcgcttca
    23161 tctttcgcct gttcgatctc gtccagttct tcgcgcagtt ccagctgttc catcaggaac
    23221 gcggtgtcgc gcacagtatg ctgctcgctg gcgagatcaa aaccgtgcaa agaaagcaaa
    23281 tattccgcgc gcattaacgg atgacgcagc gtttgccagg cctggttaat ggtcgcggat
    23341 tgctgtacgg cggcgagttg ttccgcctgg cttccgctgg cgaatttatc aggatgatac
    23401 tgacgttgta gatcctgaaa acgcaggctc agcgcctggg tatcgagttg ataacgggca
    23461 ggcaagccaa agagggtgaa gtaatccata acattctcag ggctgcgatc cgccgcgata
    23521 acggcgaatc aggtaaaaca aaccccacgc gcaggcgacc acggtggggt tatcggtatg
    23581 cgcatcaaac gtggaagctt tcgccgcaac cacactcatc tttgacgttc gggttggtga
    23641 atttaaaccc ttcgttaagg ccttctttga cgaagtccag ctgcgtaccg tccagaaatt
    23701 gcaggctttt gccatcgacc acgactttca cgcctttgtc ttcaaacacg atgtcttccg
    23761 gcgtcggttc gtcaacaaat tccagtacat aagccatacc tgaacacccg gaggttctca
    23821 cgcccagacg caggccaaac cctttaccgc ggttagccag aaaggtattt actcgcgctg
    23881 ctgcactgtc gctcagtgta atcgacataa ccaaacctca actcttattt tgcttcacgt
    23941 ttgcttttat agtccgcaat ggcggctttg atcgcgtctt ctgccagaat agaacagtga
    24001 attttcaccg gcggcagttc aagttcttca gcaatatcgg tgtttttgat cgcctgcgct
    24061 tcgtcgagag acttcccttt cacccattcg gtgaccaggg agctggaagc gatagcggaa
    24121 ccgcagccgt aagttttaaa acgcgcgtct tcaatgatac cttcatcgtt gactttaatc
    24181 tgcaacttca tcacgtcgcc acaggccggt gcacccacca tgccgctgcc gacgttctcg
    24241 tcgttgttgt caaaggaacc cacgttacgc ggattctcgt aatggtcgat aactttttcg
    24301 ctgtaagcca ttataaattc tcctgattcc gataccgatt aatgatgagc ccattcgatg
    24361 ctgttcagat ccacgccctg cttgtacatt tcccacagcg gagaaaggtc acgcagacga
    24421 ccgatggatt tacgaactaa ctcgatggtg tagtcgatct cttcttcagt agtaaaacga
    24481 cctaaagaga aacggataga gctatgtgcc agctcgtcgt tcagccccag cgcgcgcagc
    24541 acgtaggacg gttcgaggct tgctgacgta caggcggaac ctgaagaaac cgcgaggtct
    24601 ttcagcgcca taatcagcga ctcaccttca acgtagttga agctgacgtt gagaatgttc
    24661 ggcgcaccgt gttccaggtc accgttcagg taaacttctt cgatatcttt gatgccgttc
    24721 cacagacgat tacgcaggcc gcgcagacgt tccatctcgg tcgccatctc ttcttttgcg
    24781 atgcgatagg cttcgcccat accgacgatc tggtgaacag gcagagtgcc ggaacgcata
    24841 ccgcgctcgt gaccgccgcc atgcatttgt gcttcgatac gtacgcgcgg tttacgacgc
    24901 acatacagcg caccaatacc tttcgggcca tagattttgt gaccggagaa agacatcagg
    24961 tcaactttca actggctcag atcgatcggc agtttgccca cgctctgggt tgcatcaacg
    25021 tgatagataa tgccacgagc acggcacatt tcgccgatag ccgcgatatc ctgcaccacg
    25081 ccgatttcgt tatttacgtg catgatggaa acaaggatgg tgtcgtcacg catcgctgct
    25141 tcgagttctt tcaggtcgat aataccgtta cgctgcggtg ccaggtaagt gacttcaaaa
    25201 ccttcgcgct ccagctgacg gcaggtatcc agtaccgctt tatgttcggt tttactggtg
    25261 atgatgtgct tgcctttttt ctgataaaag ttggctgcac ctttgatcgc caggttgtca
    25321 gattcggttg caccagaggt aaagacgatt tcacgcggat cagcgccgac cagatcggca
    25381 atctgattac gggcgatatc taccgcttct tcagcctgcc agccgaaacg gtgagaacgg
    25441 gaggccgggt taccaaaggt tccgtccatc gtcataaact gcatcatttt ctcggcaaca
    25501 cgcgggtcca ccggcgtggt tgcggagtag tcgagataaa tcggtaattt cattgctcta
    25561 taaactccgt acatcactca atgcaaggaa ccaggctacc ggctggatgt acgaccgtgt
    25621 ttacggagtg tttagcactc cggcctgatt ctgaattctt tttattaagc gcgtaactta
    25681 acgtcgatcg cgtcttgtgt gcgggtgcgt ggcgcgtcgt gagtatgctg acgaccagac
    25741 acatccagca cttcctggtt attaaccagt tcgcctaaag taatgttatt gagaaaaccg
    25801 gtaagacggt cgctcaaatc acgccacagc gcgtgggtca ggcatttatc gccgccctgg
    25861 cagccgcctt taccctgaca acgggtggca tctacagatt cgtcaacggc gctaatcacc
    25921 tcgccaacgg cgatgctgct ggcatctttg cctaacagat aaccaccgcc tggtccacgt
    25981 acgctggaaa ccagaccatt tttacgcaga cgggaaaaca gttgttccag ataagaaagg
    26041 gaaattccct gacgttcgga aatatcagcc aacggtaccg ggcccgcttc agagttgagc
    26101 gcaacgtcaa gcattgcggt cacggcatag cgccctttag atgtcagtct catgtcttac
    26161 ttcacctcaa actcgcccct gcccggggtt ttttattgta aaagtggggg tattgcatag
    26221 cagggtcaag tctgacattc ccgagtaaat tggtcaacta tttacttgac tgatttagtc
    26281 gggtatttaa ccttcagtgc cattttttta tcgtggcgtt tgtacctgtt gtcggatgcg
    26341 gtgtgaacac cttatccgac ctgggattcc gtgcacttac aggcctgata agacgcgtta
    26401 agcatcgcat caggcaacca ctgttattcg gccttgttac ctttattctg ctgctcaata
    26461 gaagccagaa tcccgcgcag gatattcaat tcctggcttt ccgggcgcgc acgggtaaac
    26521 agacggcgca atttattcat cacctgtccc ggatggtttt cacggataaa accggttgcc
    26581 agcagcgttt gctccagatg accataaaaa cgctccagat catcgaccag cggatacggc
    26641 gtctcttcat gctcgacctg ctcgccattt tcctgagttg ccagccaggc catgcgcact
    26701 tcataggcaa taacctgaac cgccatcgcc aggttcagcg aactgtattc cgggttagcc
    26761 gcaattgcga catgataatg gcatttctgc aactcttcat tggtcaagcc gacgcgctcg
    26821 cgaccaaaca ccagcgccac cggggtattt gccgcttcag cgacgctttt cagaccgcat
    26881 tcgcgcgggt cgagcatcgg ccacggcagc gtgcgggagc gagcgctggt gcccaccacc
    26941 agactacaac cggctaacgc ttcgtcgagc gtatcgacga tgtgagcatt accaatcaca
    27001 tcgctggccc ctgctgccag ggcaatcgcc tgggagtcag gtttcactag tggattaacc
    27061 agccacagat tggttaatcc cattgttttc atggcacggg caacagaacc catattgccg
    27121 gtgtgtgacg tctccaccag cacaattcga atattttgca gcattgtctt tcttcatcta
    27181 aagattattc acgcatctta tcataaaacg aagacagatg ccgatctcgc tgctatactc
    27241 tgcgccgttt tcccgttctt taacatccag tgagagagac cgatgcatcc gatgctgaac
    27301 atcgccgtgc gcgcagcgcg caaggcgggt aatttaattg ccaaaaacta tgaaaccccg
    27361 gacgctgtag aagcgagcca gaaaggcagt aacgatttcg tgaccaacgt agataaagct
    27421 gccgaagcgg tgattatcga cacgattcgt aaatcttacc cacagcacac catcatcacc
    27481 gaagaaagcg gtgaacttga aggtactgat caggatgttc aatgggttat cgatccactg
    27541 gatggcacta ccaactttat caaacgtctg ccgcacttcg cggtatctat cgccgttcgt
    27601 atcaaaggcc gcaccgaagt tgctgtggta tacgatccta tgcgtaacga actgttcacc
    27661 gccactcgcg gtcagggcgc acagctgaac ggctaccgtc tgcgcggcag caccgctcgc
    27721 gatctcgacg gtactattct ggcgaccggc ttcccgttca aagcaaaaca gtacgccact
    27781 acctacatca acatcgtcgg caaactgttt aacgaatgtg cagacttccg tcgtaccggt
    27841 tctgcggcgc tggatctggc ttacgtcgct gcgggtcgtg ttgacggttt ctttgaaatc
    27901 ggtctgcgcc cgtgggattt cgcggcaggc gagctgctgg ttcgtgaagc aggcggcatc
    27961 gtcagcgact tcaccggtgg tcataactat atgctgaccg gtaacatcgt tgctggtaac
    28021 ccgcgcgttg ttaaagccat gctggcgaac atgcgtgacg agttaagcga cgctctgaag
    28081 cgttaatgac tcaggcgggt gatatcactc acccgccctc gcctttcagg cgctattccg
    28141 aaatacttcc tcaccgcttt actttctttc gtcactctcc caccatcttt cgccgattaa
    28201 tggatgataa agaagtcgca aggaaaggtt atggcgctgc cagtgaacaa acgcgttctc
    28261 aaaattctgt ttattctctt tgttgttgcc ttctgcgttt atttagtgcc gcgcgtcgcc
    28321 atcaacttct tctattatcc tgacgataaa atatacggtc ccgacccctg gtcggcggaa
    28381 tccgtcgaat ttacggctaa ggacggtact cgtctgcaag gctggtttat tccttcttcg
    28441 acgggccctg ctgacaacgc catcgcaacc atcattcatg ctcacggcaa tgccggaaat
    28501 atgtccgccc actggccgct ggtcagttgg ttacccgagc gtaatttcaa cgtttttatg
    28561 tttgattatc gcgggtttgg taaatcaaaa ggcacgccgt ccctggccgg attgctggac
    28621 gatacgcaaa gtgccatcaa tgtggtgcgc catcgcagtg atgtaaaccc acaacggctg
    28681 gtgctgttcg ggcagagtat tggcggggcg aatattctgg atgttattgg tcagggtgat
    28741 cgtgaaggca tacgtgcggt gatcctcgac tccacctttg cctcttatgc gaccattgcc
    28801 aaccagatga tccccggcag tggctactta cttgatgaga gttacagcgg cgaaaattac
    28861 atcgccagcg tcagcccgat cccgctttta ctcattcacg gtaaagctga tcacgttatc
    28921 ccatggcagc acagcgaaaa gttgtatagc ctggcaaaag agccaaaacg gttgatccta
    28981 atcccggatg gcgaacacat tgatgctttt tccgatcgtc acggcgatgt ttatcgcgaa
    29041 cagatggtgg attttatcct tagcgcattg aatccgcaga actaacccat gatcgctagc
    29101 acgataatca ttcacaaaac caccttaaga catgctaatc cactggtcag aacagtttaa
    29161 gatgagaaaa attctgtgat gcttgccaac atttctgatg attagcattc ccttcgccat
    29221 ttccctgagc aaactttagc tattcttatc aattatgctt atgggagatc tacagatgat
    29281 gcctacgctt gctccaccat ctgtcctttc ggctccccag cgccgctgcc agatcttgct
    29341 gacgctcttt cagccggggt tgaccgccac cacggcaact ttcagcgagc ttaatggtgt
    29401 ggatgatgat atcgccagtc ttgatatcag cgaaacagga cgggagatcc tgcgctatca
    29461 tcaactcaca ctgacgactg gttatgacgg cagctaccgg gttgaaggta cagtgcttaa
    29521 ccaacgtttg tgtttatttc actggctacg acgtggtttc cgtctgtgtc cgtcatttat
    29581 taccagccga ttcacccccg ccctgaagag tgaactgaag cggcgcggaa ttgcgcgtaa
    29641 cttttacgac gataccaatc tacaagcgtt agtgaatctc tgctcccgac ggctgcaaaa
    29701 acgctttgaa acgcgcgata ttcatttcct gtgtctgtat ttgcaatatt gtttgttgca
    29761 acatcacgct ggaattacgc ctcagtttaa tccgctccaa cgtcgctggg cggaatcctg
    29821 ccttgaattt caggtagcgc aggaaattgg acgccactgg cagcgtcggg cgctccagcc
    29881 tgtaccgcct gatgagccac tatttatggc actacttttt tccatgttgc gggttcccga
    29941 tccactgcgg gatgcgcatc agcgggacag acaactgcgt cagtctatca aacgtctggt
    30001 aaaccatttt cgtgagctgg gaaatgttcg tttttatgat gaacaggggt tatgcgatca
    30061 gctttatacc cacctcgccc aggcgttaaa tcgcagtttg tttgccatcg gtattgataa
    30121 caccctgccg gaagagttcg cccgcctgta tccacgcctg gtgcgcacca cccgcgcggc
    30181 gctggccgga tttgaaagtg aatacggcgt ccatctttct gatgaggaaa gcggtctggt
    30241 cgcggtgatt tttggtgcct ggctaatgca ggaaaacgac ctgcatgaga aacagattat
    30301 tctactgacc gggaatgata gcgagcgaga agcgcagatt gagcagcagc tacgcgaact
    30361 aacgttactg ccgctcaaca ttaaacatat gtcggtaaag gcatttttgc agacaggcgc
    30421 tccgcgcggc gcggcactga ttattgcgcc ttataccatg ccgttaccgc tcttttcacc
    30481 accgctgatc tatacggacc tgacgttgac aacacatcaa caggagcaga tccgcaaaat
    30541 gctcgaatca gcatgaggga acaactttcg ggcgcaaaaa cattgccgga agcgccacca
    30601 gcgccatcac ccagaacacg ccgtggccga gatattgata caggaaaccg gcgaaaacgg
    30661 tcatgatggc gatactgccg cccatcgcga cggcagagta aaccgcctgt aaacggatga
    30721 cttcgctacc ctggcgagca gcaatatagc gcatggcagc caggtggcag accgtgaagg
    30781 taccgcaatg cagaatttgc accactatca accacggcaa cgccgtcgtt gctcccataa
    30841 tgccccagcg cactacgccg caaatcgccg agatcaacag catatcgcgt gcactacaac
    30901 ggcggaaaag tttattactc agcgcaaaaa taatgacttc cgccaccacg cccagcgacc
    30961 acaaataccc caccgccgag gccgagtagc cagctgcctg ccagtaaatg gcgctaaaac
    31021 cgtaataggc cgcatgtgcc ccctgcaata aacaaacgca ggccagaaag cgccagttct
    31081 ggcgaaccaa cgccaaccac gcagaccagc cggtgctctc ctgctggcgg cttgcccctt
    31141 gtggctgaat cgtcggacgg atgagaaagc cgagcagcat ggatgccacg cccaacgtca
    31201 acagcgcgag gatcacccga taatcaaaca tactgaccag tttgcccgtc agcgccgagc
    31261 caatgacaaa cgccaccgag ccccacagtc tcactttgcc gtaatcaagc gggaactgct
    31321 tttgccacgt attcgccagt gcatcggtca acggtaccag cggtgagaaa aagaggttaa
    31381 agccaatcat caccagcatt agccacgcta cgtgcgcccc cgcccagaag gcgacagcaa
    31441 agagaagtgt cagcagtgcc agcacgcgca aggcggaaat caggcgggaa ggatcgctga
    31501 cgcggggcgc gatgagcaaa ctcccgagga aacgggcaac cagacccgcc cccaataaca
    31561 ggccgatggt ttctggcgtt aaaccaatcc ctttaagcca gacgctccag aaaggtagaa
    31621 aaatgccgta actaaaaaag tatgtgaaat agccgagcgc caaccagcgc gtggattgca
    31681 aaaccatgag tccctcccgt caggaggcgt tagtctgggg ttaatcgaat gttggtgcaa
    31741 gttgaaaaat aagaatattc gagcctgctt cctgacggtt atcctgcata tcaggaaatg
    31801 acaaaaaagt gcggcccaca acacaacatg taaaaaagaa cgatgaaaca ggtgaaaatc
    31861 gcaatttatt gaactgacaa actcatgtga gacggataag gcgtgcatgt cgcattcggc
    31921 aggaaacaat aagcacattg tcagccatct gcgttatgcc gttataccag aaacgaatat
    31981 ctcaacgcct ggggcgtggc gaggtaccag agtgtgtatt acgtttaaat cacatcatct
    32041 tgcaaaggga ttggttatga actcactacg ttattttgat tttggcactg cccgccccgt
    32101 tttattatta attgcccgta tcgccgtggt cttaattttc attatttttg gttttcccaa
    32161 aatgatgggc tttgacggta cggtccaata tatggcctcg ctgggcgcgc caatgccgat
    32221 gctggcagcg attattgcgg tagttatgga agtgcccgcc gcgatattaa tcgtgcttgg
    32281 ctttttcacc cgtccgctgg cggtgctgtt tattttctac acgctgggta cggcggtgat
    32341 tggtcaccat tactgggata tgaccggcga tgcggttggg ccaaatatga ttaatttctg
    32401 gaagaatgtc agtatcgctg gcgcattcct gctgttggca attaccgggc cgggggcgat
    32461 ttctctcgat cgccgttagg aaagatgccg gatgtggcgt gaacgcctta tccggcattt
    32521 tataaattac agcaacgcaa cccgcaacga catctctgaa attgttgatt cccctggtgc
    32581 aagcgcaatg aggtcaccac cttccgggcg atgatggtca tccggcgcat gactcatcgg
    32641 ttccagacag aagaaatcaa acgcatatcc tttatcaaac gcagggtctg aaacaaagat
    32701 gaaataacac ggtgcaggtg gcgtcgtttc catgatgatg gcatacccct cctgcggctg
    32761 ctcgatgcgg gccttaccat tccatccggc aaaaccattg tttacccact ggcgcggcaa
    32821 cggcgcgagc tggttaaaat ccagctcctg cggtagctgc tcgcaaaact cacccgccag
    32881 ccactgctcc cgctccagcc agtaaccgct cgcctgtgcc tgaatccgcg tttgcggcga
    32941 caacggaaaa taaggatgcc agccggtacc aaatggcagc gtctctgccc cttgattggt
    33001 gacagcgagc gtcaccgtca gcgtatccgc cgttaaatga aatgcctggc ttacccgata
    33061 gtgataaaca ccgctgagat gttcatacac cagacacaag ctatcatcgc tgcgcgagac
    33121 acattgccac tcgcccaacc agccatcgcc gtgtagatag tgcgcatccc actcaacatt
    33181 cggttgcagt tgatactcac gcccctgcca gacaaaacgg ttgccgctca cccggtttgc
    33241 aaatggtacc agcggaaaac aagaggcatc ggttgccaca ccgctttttt taccaggacg
    33301 tagcagcggc gtcgtatcgc gccagaagcc ttcgattacg ccgccctgat cagaaacgtc
    33361 cagctttagc ggcccgtgag ataaggtata gatggtcatc cgcagactcc ttaatccggg
    33421 aaattaatca caactttccc acatttgccg cttgccatca gtgcataagc atctcctgcc
    33481 tgttccagcg agaaacgatg ggtaatggcg ttacgcggcc acagtttcca gtccgttaaa
    33541 tcgtgggcgc atttttccat atggaacaaa ctggtcaccc aggagccaat aatccgccgt
    33601 tgatggtgca tcaggtcagc gctaacctcg aactcgactt ttccggtttc accaatgtaa
    33661 accacgcgtc cccagtcagc tgtggattgc agtgccagta agcgacctgc ggcattaccg
    33721 gaacaatcaa gcgcaacatc cgcgccgccg tgagtgagtt cggcgattat ctgcggcaga
    33781 ccttcggtgg tcgctaaata gccgtgatcc atcactccta actgtttcgc catcgccaga
    33841 cgttccggca gcatatcaac gccgatgatc ctttttgcac cacgaccttt cgccagcatc
    33901 atcgccatca tgccgaccgg ccccagaccg accaccagca cgttatcgct accggaaact
    33961 tcgccgcgca aaatcccttc atacgctgta ccaacgccgc aactgataaa cgcaccatct
    34021 tcatagctca gcgcgtccgg cagcaggatc agatcttttt cttccgccag caggtattca
    34081 gcatggccgc cgtcacgctg ccagccgtaa gccgcttttc cttcgccagt acaagaaata
    34141 ggaaaaccgc gacggcagtt cgggcaaaaa ccacagccag aaatgtgata caccagcacg
    34201 cggtcgccct ctttaaaatg gcggcagcct tgccccatcg ccacaatctg cccgcacggt
    34261 tcatgaccgt tgataaatcc ctggtataac ggtttatcgg gtgccgccgc cgtagcgcgg
    34321 tgctggtggt agatatagtg gacatcgctt ccgcaaatcc cggaggattt cattttgatc
    34381 agtacctggt taatccccgg cgtcggcacc gcaacttccc gcagatcgac ggtcgaattt
    34441 cctggtaaat aagctgccag catcgttttc ataaatccct cattaacaat acgattaatt
    34501 ttcatccctg ccgcacccgc gccaggggcg ttaaggttta gcgtttcgct ttactactac
    34561 gctgggtcag caagatattt gccagcaccg ccaccacaat gatgacgccg cgcaccacct
    34621 gctggaaaaa ggagttaatc ccgagcagca ccagaccgtt accgattagc gtaatcacca
    34681 gtacgccaag cagcgtaccg aacaacgagc cgcgaccgcc ggaaagcgcc gtaccgccga
    34741 ccacgaccgc ggcgatgacg tcaaactcca gaccgtttgc ggcacctgcg ttaccggaac
    34801 cgaggcgcgc cgccaacaaa atgccggtca ccgccgctaa taatcccgaa agggtaaaaa
    34861 taagaatgcg tacccgacga acgttaatac cgcacaactg cgctgcagtg gcattaccgc
    34921 caacagcaaa aaccgagcgc ccgaaggcgg ttttgcggct aatgaacaca aacagcgcaa
    34981 ataacaccat catgatcagc gcggataccg gcacaccgag aaattgtccg cccagccagt
    35041 ccagcacttc gttttcgtta attggcactg gcaaggcgtt cgtcataaac agccccattc
    35101 cgcgcagggc gctccataaa cccagcgtgg caacaaaact tggcacgtta aacacgccgc
    35161 gcagcacccc ggcgagcgtt cccatcagcg cacctaacag caacaccagc agacaagcaa
    35221 tcgccagcgg aacttcaaat tgcagcaaaa acgccaggca cactgaaaca aaagccacca
    35281 tcggcccaac gctgacatca atttcaccgg agataataat cagcgtcatc gcccaggcgg
    35341 cgatcccgat ggtggcggca tcgcgcagca cgttcatttg gttattcaat gagataaagc
    35401 caggcgcatt cagggagaag accagataaa gaatggcaat caccaccagc aaaccgatct
    35461 cattaatatg gcgactgaca aattgtttga gcgagacgct cttgccctgc ggcaatggta
    35521 atgacgaagc agacatcttc aggttcctcg gtaaaattca tcagtggaca gaatggcgga
    35581 catcagctca tccacattga ccggcgagtg aaactcctgc gagaacgtgc cgtgctgtaa
    35641 taacaggatg cggtcacaca ccagcggcaa ctcctccact tcactggaga taaacaccac
    35701 gctttttcct tcggcagcca gctcgcggac aatacggtaa atctgctgtt tggcttcgat
    35761 atcgacgccg cgcgttggct cgtcgagcaa caaaatctgg ctggcggcat agacccaacg
    35821 accgatcacc actttttgct gattgccgcc agaaagcgtg ccgatgggcg tttcgctact
    35881 ggcggccttg accgtcatcc gctgcatcac ctcttcggtc aggcggcgga tggtggacca
    35941 ttgcagcaca ccgttggcgc tgattttttg ccgattggtc agcactgtat tttcgtcaac
    36001 gcccaaccag ggaatgatcc ccgcttcttt gcggttttct ggcgtatagc caatgccgcg
    36061 tttcagcatg tcgccgtaat cggggcgcat gattttctcg ccgttgataa caatttcgcc
    36121 ctgttcatac gtctccagac caacaatcgc cttcagcaat tcactgcgcc ctgcccccag
    36181 cagaccagca atgccgagca cttcgccacg acgtagcgta aaactgatat cctccagctt
    36241 gggcttatgg cgtaacgcac ggacttccag cacggcttga tccataattt cctgaggggc
    36301 aaccggcgca atatcaacgt gatcgcgccc gagcattagc gacacaatat gatgcgtaga
    36361 ggtgttttcg agcatcacat cgcccgccac ctgaccatcg cgcataacgg tggcacagga
    36421 ggcaatgcgg cgaatttctt ccatccggtg gctgacataa atcaccgcca cgcccagtgc
    36481 cgacatcttt ttcaccgcgc tgatcaccag ttcaacttcc gcactggcaa gcgagctggt
    36541 gggttcatca agaatgacca cgcgcggctc gcccttcatc acccgcgcaa tttccaccag
    36601 ttgcttttgc gccgggctta gcgttgaaac aagttgttca gggctaacgt caacgcccag
    36661 cgcctgtaag caacgttggg catcctgcgc catttgcagg taatcaatca tgccgttgcg
    36721 gcggggccac tgaccgaggc agaggttttc cgccactgtc agcccttcca ccagacttaa
    36781 ctcctgataa accgcgcgta cccccagttc agcggcacgg cgagtcagcg tagcttcgtc
    36841 accttccagt cgcgtctcgc caatccagat atcaccgcta tccggacgtt cgctaccggt
    36901 aagcattcga atgagggtcg attttcccgc accgtttttg cctaacagcg cacgaacttc
    36961 gccttttttg agcgtgaagt taacgttatc cagcgcaacg actccgggat aacgcttatt
    37021 tcctgccacc acttttgcta ccgggactgc ctctgttgcc gtgaacatag ggacctctgc
    37081 gaatcagcga ttagggcaga ccatcaacgt gcgttgccag ccactgttta ccgtcttccg
    37141 ttttggtata gagatcgatt ggcacctgaa tcactttttc accgtcggct tgtttattga
    37201 taaccttcaa tgtttgcgta aaaacagcat tgcccatttt cttaccagaa atatccacca
    37261 ccgctttcag cacctggttg ttttccagct cctgagcaat ttcagtggtc atatcagaac
    37321 cgaaaacagc aatttttccg gcctgatttt gattacgtac cgcttttacc gcgccgagtg
    37381 tcgctccgcc cgattccccc ataatggcgt tgagatccgg cgtggagata atcagttttt
    37441 caccgacaga aatcgcttta tctaaaacag tcccttcctg attagcgaca atttgcgcgc
    37501 cgggaacgcg ggtttttaat acttcttcaa accctttacg acgttgcaca caaacttcaa
    37561 aggcttcgca attgatgacg gcaattttcg gctggtcaat tttgttggca ataaaataat
    37621 cggcggcagc gttacccagt tttttaccaa attccagcgg gtcaccaacc agatatgccg
    37681 agacatattt atcgacaccc ttttgattaa tacaggtgtt gtagcaaatc accggaatac
    37741 ccgcttcact ggcgcgacga acggtacggc tactgccatt ttcagacact gccgataaaa
    37801 taatggcatc gacattacgc gccacgaggg tatcaacaaa ggtactttct ttcgaaatat
    37861 cgccctgagc gttagtttca attaactgta cctgtactga agaatctttt gccgcatcct
    37921 gaacgccctg acgcactccg gcgtaatatc cctgggtatc aaggtatatt gcgccaatag
    37981 tcatttcttt atcagaagcc ctggcaaata gtgcgctacc caatagtgta gccattaata
    38041 ataaattacg ggttcttgtc atttttttag gcatagtgcc tcctgtaggg tttttattta
    38101 caacggctta ttttaattat ttgagcgtga gcggcagcac gtgccgctca aatattacag
    38161 ttaatagggt ttagtgaacg tagctaaaaa taaaaggcat cacggtggtg aataatgccg
    38221 ctttcggcca ggctggatta atcgccatca attcagcgcg agcagattca tagtgcgcaa
    38281 cctcccctaa tcccgcggcc gccagcatcg ccaccatcag gcatttttct ttatgctgct
    38341 gttgtaaatc gccatacagc gacaacaagt caggctgcga gacggcaaag aaatccgcct
    38401 cgatactggt tttcgccatc tcttgtgccc actgtttcat ttcactaaac agttgctgtg
    38461 cagtttgttg ttcgcccagc agtcgcagcg ccattccttg ccagaagaga taatcaaccg
    38521 gctgatcgtt gtaataactg tggatgttaa tggtgcgatc gccggtcgcc gccagacgta
    38581 aacaacgcgt cgcttcagtt tcatcgccct gcgcgttggc gcatactgcc tgccagaacc
    38641 agatgtcgtt gtcagtttgc cccggtaaac ggccttcgct taaattctcc ggataatgca
    38701 gcgcggcatg aagcagttcg ctggcctgct gcggctctct gtcatcaaga tgctgccagg
    38761 cgcgtaataa ctggttgagg ataaactggc tggtgacctt cccttcccca ccttcccacg
    38821 ggtggaattt gcgcgtggcg agaatgtccg ccgctttgtc tgcctgaccc gtgagatgcc
    38881 acaaattgag cagttctgcg gtcatgtcgt cgcgtttcag cgcaatttcc agattatctt
    38941 ccagacgcgc cagtcgtttc tccggtgtga caccgcttaa cttatccagc aaatcccgtt
    39001 cgaaaagcag acgtgcatcc tgcggcgcaa gctgataagc attatcaaga taacgcgcgg
    39061 ccagctcata atcgtgctgc ttattccacg catggatcgc caacccgcgc cagccgtcgg
    39121 caaactccgg cgacatctct acgcaacgct gccataaggc aatggctttg ccgtagctac
    39181 gcttgttgta gtagaagcag gccagtaaat gccgggcaaa ccagcactct tcgatactct
    39241 ccagcgccgc cacttcttcc agcgtattcg ggaaacggac aaactgcggg aaggcatcaa
    39301 tagcttttgc gaccagttct ccgcgttcag cttttggtag caaactggct tgcaggtaaa
    39361 gcggtagcgt gcgctgacag tccagtgcgt tcagcatatc tgccgccagg gcgggcatgc
    39421 cccagttaat cagttgcccg gcggtcatca gggcgttaac gtcgcgtccc tgacaaagac
    39481 ctcgccactg cgcgagggct gattcgctac gaccatcgaa ccagttcagc caccacagag
    39541 tggcgttcag cggataatca cgcagcagtt tctcgcgctg caaacgcgcg ttgtcctgac
    39601 gaccacttaa caccagtagc aggttatgca ggcaaagcac ttcctgattg gttgggcagg
    39661 cgcgaagact ttgttggcaa aaatccagac cagcgtcgaa gttaccatta cgcgccgcca
    39721 gtcgtgccag accataatag ccgcccgctt tactgttgcc gctccagacc gcacgccaga
    39781 aatcctcttc ggcttgttga tattgcccct gacgttcgta agcactggcg cgaatcaaac
    39841 tcgcctgtcc gcactgcgga tttttgttca gcgcatgtgc gcgtttcagt gcctgactgg
    39901 catataccac cgcttgcggg aaatctgcac ggttatattc cagcattgcc agcgccagat
    39961 tacagcgata atccagcgga tccagcgcca cgccgcgcag gtagtaatcg aacggtgaac
    40021 ggctggcgtg atgatattgc tccagatgtt gaccgataaa ccaggcttca tctgtactgg
    40081 taatgtcttg tgctgccagt ggcgctttgg cgacgtccgg caacggcaac gcttgcggct
    40141 gatgttcatg ataactcagt acaatattgc cgtcggcatc ggagagctca atggtcagcc
    40201 tttcaggatt gataccgtgc aacacgccct ggatggcggt cgctggtgtc agggccacgg
    40261 catcatcgag caacgcgttg catttgccga tttcgcggat cgccaggcgg tatccgttca
    40321 acggagagat ggcatacagc ccccactcaa tcccccgctc actacgctgg agttttatca
    40381 ccgcatcgcg ggaggcattt tgcaccatgc ccagagaatg ataaggcagg aaatactgct
    40441 cgaaacgctt ctcctcgtaa gcatcaagcc aggtaaaatc aggctggtta tcggcaaaaa
    40501 taccggtcat cagttcgata tacgggccgt tattgtcagt caggctctta tcccacgcct
    40561 ggccaaattc actgtgtccc cagctccact gttttttacc tggcgcaata tggtggttgg
    40621 caacgtgtag caaaccacca tcttcatcgt gacaccacgc gccaacaaaa tcgtactgtg
    40681 atttttcagc catatatgag gttggaacgg gcacattttt atagcgagaa atgtccactc
    40741 cggcggagta gtccactttg tagtaagtgc cggtggcgat ggggaaagcg gagacggccc
    40801 gtttgccgtg atcaaacacc gccgttacat ccggcgggaa gacgctctga tgcccttccc
    40861 cccctttcac tgccgggttg gcccaccaca agaaatgacg cggcgtggcg ttgccgttat
    40921 agacgcgact ggcgatttcc agcgccgccc ggtcagggcg cagggtgaaa cctgtcatca
    40981 cctgtaaacc gtgcatcgac tccgtttcgc cgacccacac cgtctgtgcg ccgtcgtcat
    41041 gggcttcgag ggtgaaatca acgggcataa aggtggtcgg gcgatggtgt tgcggccagt
    41101 taaactcaat cccgccggag atccacggcc ccagcagtcc caccagcgcc ggtttaatga
    41161 cttcattgtg ataaacaaaa tcgcgctgtt tcactttatc ccacgcgcga tgcacccgac
    41221 cgcccagttc cggcaggatc atcactttga tgtagtcgtt ttccagccac accgcctgcc
    41281 aggatttcag ggttttctgc tcgctcagcg tatcggtcac gccgtaggga taaaccgcgc
    41341 cggacgatcc ctgataaacg cgattttcca ggaacatggg atgtatatcc tgcggcccgg
    41401 tttcataggt cgggatctca acgcgctctt gccacacttt tactggagtc atggtgccct
    41461 caatattaac aagacatact gaattaaaag atttgtggca gtgtattgaa caatctggca
    41521 atgttttcgc ggaataatca cgcaattaac taaacaaggt ttagtgaaga tgagagcctg
    41581 cattaacaat caacagattc gccaccataa caaatgcgtg attctggaac tgctgtaccg
    41641 gcaaaagcgc gccaataaat caacgctggc ccggctggcg caaatttcga ttccggcggt
    41701 cagtaatatt ttgcaggaac tggaaagcga aaaacgggtg gtgaatatcg acgatgaaag
    41761 tcaaacgcgc ggacatagta gcggtacatg gctgattgcg ccggaaggtg actggacgct
    41821 gtgtctgaac gtgacgccca ccagcattga gtgtcaggtc gctaatgcct gtttaagtcc
    41881 gaaaggcgaa tttgagtatt tacagattga tgcaccgacg ccgcaggcgc tgctgtccga
    41941 aatcgaaaaa tgctggcatc gccaccgtaa attgtggccg gatcgcacca tcaatctggc
    42001 tctggcaatc cacggtcagg tggatccggt gaccggcgtg tcgcaaacca tgccgcaagc
    42061 gccgtgggca acaccgattg aggtgaagta cctgctggaa gagaagctgg gtattcgggt
    42121 aatggtcgat aatgactgcg tgatgctggc gctggcggag aaatggcaaa ataattcgca
    42181 agtgcgtgat ttctgcgtaa tcaacgttga ttacggcatt ggctcgtcgt tcgtgattaa
    42241 cgagcaaatt tatcgcggca gtttgtatgg cagtggacag attggccaca ccatcgttaa
    42301 tccggatggc gtcgtctgcg actgcgggcg ttatggctgc ctggaaaccg tcgcctcgtt
    42361 aagcgcatta aaaaaacagg cgcgggtatg gctaaaatca caaccggtta atactcagct
    42421 taatcctgaa aaattgacta ccgcgcagtt aatcgctgcc tggcagagtg gagaaccgtg
    42481 gttcaccagt tgggttgacc acagtgccaa cgccattggt ttgagtctgt ataacttcct
    42541 caacatcctc aatattaatc agatttggtt gtacggtcgc agttgtgcct ttggtgagaa
    42601 ctggcttaat accattattc gccagacggg atttaacccg ttcgaccgcg acgaaggacc
    42661 gagcgtgaaa gcgacacaga ttggctttgg gcaattaagc cgcgcacaac aggtactggg
    42721 aattggctat ttgtatgttg aggcgcagtt acggcagatt tgatggcgcg ataacgtaga
    42781 aaggcttccc gaaggaagcc ttttttcaac agattaaccg tttcgcttat gcgtaaaccg
    42841 ggtaacgtgc gcagatgtcg agaactttac ctttgatgcg ctcgataacg gcttcatcat
    42901 tgatgctgtc cagcacgtca cacatccagc cagccagttc tttcgcttcg gcttctttaa
    42961 agccacgacg ggtaatcgcc ggagtaccta cacgaatacc ggaagtcaca aatgggctct
    43021 tcggatcgtt cggtacgctg tttttgttga cggtgatgtt agcacggccc agagcggcgt
    43081 ctgcttcttt accggtcagg tttttatcaa ccagatcaac caggaacagg tggttatcag
    43141 taccgccgga aaccactttg tagccgcgtt cgaggaacac ttctaccatc gctttggcgt
    43201 ttttcgcgac ctgctgctgg taagttttga actcaggttc catcgcttct ttcagagcaa
    43261 ccgctttacc ggcgattacg tgcatcaacg gaccgccctg accaccaggg aaaacggcag
    43321 agttcagttt tttgtacagc tcttcgctac cacctttcgc caggatcagg ccgccgcgcg
    43381 gacccgccag ggttttgtga gtggtggtag ttactacgtg agcatgagga accgggttcg
    43441 ggtagacgcc agcagcaacc aggcccgcaa cgtgcgccat atcaacgaac aggtaagcac
    43501 cgatgctgtc agcgatttca cgcattttcg cccagtcaac cacgccggaa tatgcagaga
    43561 agccaccgat aatcattttc ggtttgtgtt ctttagcttg tttttccaga tcggcgtagt
    43621 cgatatgacc agtagcatcg ataccgtaag gaacgatgtt gtacagttta ccggagaagt
    43681 taaccggaga accgtgagtc aggtgaccgc catgcgccag attcataccc agaacggtat
    43741 cgcctggttc cagcagcgcg gtgtagaccg caaagttagc ctgggagccg gagtgcggct
    43801 ggacgttagc gtagtcagcg ccgaacagtt ctttcgcacg atcgatcgcc agttgttcaa
    43861 cgatatcaac atactcgcaa ccgccgtagt agcgtttgcc cggataacct tcagcatatt
    43921 tgttggtcag ctgagaaccc tgcgcctgca ttacgcgcgg gctggtgtag ttttcggagg
    43981 cgatcagttc gatgtgctct tcctgacgta ctttttcctg ctccatagcc tgccacagtt
    44041 cggcatcata atcggcaatg ttcatttcac gctttaacat ccgcatctcc tgactcagct
    44101 aacaataaaa tttttggcct ttataggcgg tcctgttgga caacggcgaa cagtataacc
    44161 gaatcattgt gcgataacag gtcttgacaa aggaatttac gcaaacgatt accttcaggc
    44221 tacgcaaggc tttggagaat aaagagcttg caaccggaaa cggatttctt ttcaggtttg
    44281 tgatgcaaat ttttcacttc atcacattct ttctgaaaaa caccaaagaa ccatttacat
    44341 tgcagggcta ttttttataa gatgcatttg agatacatca attaagatgc aaaaaaaagg
    44401 aagaccatat gcttgacgct caaaccatcg ctacagtaaa agccaccatc cctttactgg
    44461 tggaaacggg accaaagtta accgcccatt tctacgaccg tatgtttact cataacccag
    44521 aactcaaaga aatttttaac atgagtaacc agcgtaatgg cgatcaacgt gaagccctgt
    44581 ttaacgctgt tgccgcctac gccagcaata ttgaaaacct gcctgcgctg ctgccagcgg
    44641 tagaaaaaat cgcgcagaag cacaccagtt tccagatcaa accggaacag tacaacatcg
    44701 tcggtgaaca cctgttggca acgctggacg aaatgttcag cccggggcag gaagtgctgg
    44761 acgcgtgggg taaagcctat ggcgtactgg ctaatgtatt tatcaatcgc gaggcggaaa
    44821 tctataacga aaacgccagc aaagccggtg gctgggaagg tactcgcgat ttccgcattg
    44881 tggctaaaac accacgcagc gcacttatca ccagcttcga actggagccg gtcgacggtg
    44941 gcgcagtggc agaataccgt ccggggcaat atctcggcgt ctggctgaag ccggaaggtt
    45001 tcccgcatca ggaaattcgt cagtactctt tgactcgcaa accggatggc aaaggctatc
    45061 gtattgcggt gaaacgcgaa gagggtgggc aggtatccaa ctggctgcac aatcacgcca
    45121 atgttggcga tgtcgtgaaa ctggtcgctc cggcaggtga tttctttatg gctgtcgcag
    45181 atgacacacc agtgacgtta atctctgccg gtgtcggtca aacgccaatg ctggcaatgc
    45241 tcgacacgct ggcaaaagca ggccacacag cacaagtgaa ctggttccat gcggcagaaa
    45301 atggcgatgt tcacgccttt gccgatgaag ttaaggaact gggtcaatca ctgccacgct
    45361 ttaccgcaca cacctggtat cgtcagccga gcgaagccga tcgcgctaaa ggtcagtttg
    45421 atagcgaagg tctgatggat ttgagcaaac tggaaggtgc gttcagcgat ccgacaatgc
    45481 agttctatct ctgcggcccg gttggcttca tgcagtttgc cgcgaaacag ttagtggatt
    45541 tgggcgtgaa acaggaaaac attcattacg aatgctttgg cccgcataag gtgctgtgat
    45601 ttgatgttgc cggatggaca catccggcaa cccttgacgc gttttaaatt gccgcgtcgt
    45661 cctcttcacc ggtacggatg cgaatgaccc gtgccacgtc gaagacgaag attttaccat
    45721 caccgatttt gccggtttgc gccgtgcgaa taatggtatc gacacaggta tcgacaatgt
    45781 cgtccggtac gacaatctca attttcactt tcggcagaaa atccaccata tactccgcac
    45841 cacggtacag ctcggtatgg cctttctggc ggccaaaacc tttcacctca gtgaccgtca
    45901 tgccggtaat accgacttca gccagtgctt cgcggacatc gtccagcttg aagggtttaa
    45961 taatcgcatc aatctttttc atgctattcc ttgaaaaggt cgcctgtctt ttgatctgct
    46021 aaacgtaaca cataacgcca attcattcct tgaaatcgtt tgcatccagc tcgtttcggg
    46081 aaagcagttt ataaaattct gtccggttgc gccccgccat tctcgccgcg tgggtgacgt
    46141 tgcctttggt gatttgcagc agcttacgca aatagttgag ttcaaactga ttacgtgcct
    46201 caacaaaggt tggcagcgcc gtattttcac cctccagcgc ctgctccacc agcgcatcac
    46261 taattaccgg agatgaggtc agcgccacac actgttcaat cacgttgacc aactggcgca
    46321 cgttgcccgg ccagcttgca gtcatcaggc gtttcattgc atcggtggag aacgcgcgga
    46381 caaacggttt atgtcgctct gccgcctggc gcaacaggtg atttgccagt agcggaatgt
    46441 cttctgtgcg ctccgccagt gccggaattt tcaggctgac aacattgagg cggtaataaa
    46501 gatcttcacg gaattcccca cgcgccatcg cttttggcag gtcgcggtga gtggcggaaa
    46561 taatccgcac gtcaatatca atatcgcggt tactgcccag cgggcgcact ttacgctcct
    46621 gcaacacgcg cagcagtttg acctgcaacg gtgcaggcat atcgccaatc tcatcaagaa
    46681 atagcgtacc gccttccgcc gcctggaata aaccttcgcg attgctgaca gcgccagtaa
    46741 acgcgccacg tgcatgacca aacagctccg actccagcaa ttgctcgggt aatgcgccac
    46801 agttaatagc aataaatggc ttgctgttgc gcgggctggc gttgtggata gcctgggcga
    46861 aaatctcttt cccggtgccg ctctggccgt taatcaaaac gctaacgtct gattgtgcca
    46921 ccagccgcgc ctgttccagc aagcgcagca tcagcgggct gcgggtgaca atcgcctcgc
    46981 gccaacgttc gtcggtggct ggcgcggatt gttccagcgc atcgtcaatt gcctgatata
    47041 gcgcatcttt atcgacaggc ttggtgagaa aactgaacac gccctgctgt gttgcagcaa
    47101 cggcatcagg aatagaacca tgcgcggtaa gaataattac tggcattccc ggctgcactt
    47161 tctggatttc agcaaacagc tgcataccgt ccatttcatc catccgcagg tcgctgatga
    47221 ctaaatctac tttttcgcga ttcagtaccc gcaatccttc agcaccactt tccgccgtga
    47281 ccacactgta gccttcgctg gtcagacgca ggccaagcag tttcagcaat cccggatcgt
    47341 catcgaccag taataaatgc gcaggtttat ggctcatcag gagtgacctc atcggtggat
    47401 ggcgcgggct tttcactctc gtgcggcgta tccggcgaga aatttccagc cggtttgcgg
    47461 gtcgagagct ggcgttcaat atcggtcagg ttttccagct tgcgagtagt gagttccagt
    47521 tgctgttgta gaacgtgatg ttgctggcgc aaagtatcca gctcgctgtc gctggactgc
    47581 tggagtttgc tgtagcgttg gcgctcttcc gccagttgca gttgcagcgc ctgaccgtcg
    47641 cgccaaagtt gatacagtgg gcgaacctgt gccgggatct cggtacttag cgcatcaatg
    47701 cgcgcgacca gctggcggcg ctcatacggc gtaattttgg cgtcggcgag caaaatccct
    47761 tgtttaaagg tattttgcca gttgccgtcg tcatattggc gggcttgctg acgcgactgc
    47821 gcaggcatta aacgatcagc acaatccatc gcccgcagcc agtaaagcgg attggtttcg
    47881 gttgatttac cttgcagcgc ccagatgtcg ctacattcag tagaaagata gtcagccagt
    47941 tgataaaccg gaattttttc ttctgctggc gtatcaatgg ctggcctatt gtgactctgc
    48001 acgcaaccca gcaatgccag acatggcagc cctgccagcc acagccgtcg gggcaataat
    48061 cgttgaaaaa tgtgtcgcat attcaccaga cttaaagcct atcccagtgg gcgtaattgt
    48121 tgcaggcagt ttggacatgg acagcgcgga gaaaccggag cgtacatgtc gtacgtgaag
    48181 atttcgagca ctgcccgggg ccgaactgac aaataaaata gcctgatggg atgggctgtt
    48241 agcattattt cgtgtttttc gacgacggta attcaatgcg gaaacaaacg tcttgcccgc
    48301 tctcgtcgac cagatacagt tccccttgca tacggcgaat acaatccctg gcaatgctta
    48361 atcccagacc gctgcccttc accgcccctt ttcgctggtg gcttccctga aaaaagggtt
    48421 cgaagatcat ggcgcgttcc tcttgcggaa tgggcgtgcc tgtattgatg acatcaatat
    48481 aaacccgcgc accatgtaaa ctgctgcgaa ggcaaatgtt accggattca gccccgtagt
    48541 gcaccgcatt ggagtaaaga ttatccagta cgctcatcag cagcattggc tccgccaggc
    48601 aagctgttgc tttgagatca acgtcggtat gcatcatttt agcccgtgcg ggcaggctat
    48661 gagcagaaac caatgtctcc accagcggtg ctaactcaac attctccagt tccaccgcac
    48721 tgtccgcctg tttacggttg taatcaagca gttgttcgat cagtttttgc aaattgcggc
    48781 tgctgctatc aagaatgctc accacctctt tttgctctgg cgtaagcggc ccgacaacct
    48841 gatcagccag taattcagtg ccctcgcgca tactcgccag tggcgttttt aattcatgag
    48901 ataaatgtct taaaaattga tggcgttggg attccagcca tgacaggcgc tcacttaacc
    48961 aaagaatacg ttgcccaacc gagcgtaact cgctcggtcc actgaacgag acgctattgc
    49021 ccagagaacg cccttccccc agccggttga tcatgcgctc gatatttttc accggaccga
    49081 taatcatcct cgtgaaaagc agtaccatca ccagactcac cagaaatagc accagcgatt
    49141 gccaaccaaa atattgccca cgttcggcga tttcacgctg aagttgctgc ccacgagaga
    49201 acaccactgt gcgcgtggcc tgcaccattt cggtattggc actggcaaag gcttccagac
    49261 gcgcggcggc agcagcatcg ggaccgctgt tgttacactg aagttgagcc agattgttca
    49321 aatcctgacg taatgcctgg tagagtttat cgtccggcag cacgcctgcg tgggcatcga
    49381 gcatttcgct gtaacgcttg cgctggcttt gataaacctt cgcaagcgta gggtcgtcca
    49441 gcacgcagta ctgacggtag ctgcgctcca tctccagtgc cgcgttggtc atcgcttcac
    49501 tgcgccgggc atcaataagc gtagtgcggt taaccagcgc cgcctgatcg ctaagtgcat
    49561 tcaggctttg ccaggcttgc catgccagca ccaacagggg cagcagaatc agcaaaaatg
    49621 ccagcattac cagttgtcgt aatgagcggg gaaaaacggg ccagcgtttc aaggcgttac
    49681 tctcgtcaga cgcgaatagc ctgatgctaa ccgaggggaa gttcagatac aacaaagccg
    49741 ggaattaccc ggctttgtta tggaataagg cggtgcctaa ctcgacgttt cgcccgatgg
    49801 ttgatatagc taagctgata tcagaagttg gacggcaggc accttgttgt gcgtcattcg
    49861 aattttatgt agcacgtccc gaaggggctg acataagtcg gtgaatgagc cactgcttac
    49921 tattatgcag taactgtgcc aataaagaaa atagtttggt aacatactga ttatacgctg
    49981 ctttgagggg tttatggctt ctccgctatt tgaatgtaaa tcagccactg tgtcgctaaa
    50041 aagagacaac ttaagataaa cttattagat aatattaaaa tcaatgagtt aagtgtcacc
    50101 aaaaagcgac acggcaaacc acccattgtc gtgatttaaa gacacaaaaa agctcccgaa
    50161 gttgggagct cataatagcg gttggtgctt aatgccggat gcggcgtgaa tgcctcatcc
    50221 gggctgcaat accaatgggt tgacgactta ccccaactgc ttacgtgcat tgcggaaaat
    50281 gcgcatccat gggccatcct cgccccagtt ttccggatgc caggagttgc tgacagtacg
    50341 gaaaactcgt tccgggtgcg gcatcataat ggtgactcga ccactttcag tcgtgaccgc
    50401 cgtaataccg ttcggtgaac cgttcgggtt agccgggtag gtttcagtga ctttgccgaa
    50461 gttatcgaca tagcgcagtg ccaccagccc tttgctttcc agtgccgcca gatgcgccgc
    50521 atcacgcact tccacgcgcc cttcaccatg agacacagca atcggcatct gcgagcccac
    50581 catcccctgc aacagcagcg acgggctttg ggttacttct accagactga aacgcgcttc
    50641 aaagcgatcg gaggtgttac gcacaaaacg tggccacaac tcgctacccg ggatcagttc
    50701 acgcagatta gacatcatct ggcaaccgtt acataccccc agcgccagcg tttgcggacg
    50761 atggaagaag gttgcaaact catcgcgtac acggtcattg aacaggatag acttcgccca
    50821 accttcacca gcgcccagca catcaccgta ggagaaacca ccacacgcga ccagggcgtg
    50881 gaaaccctcc aggcccgtgc gtccagccag cagatcgctc atatgcacgt cgatagcatc
    50941 gaagcctgca cggtggaaag ctgccgccat ttcaacatgc gagttcacgc cctgctcacg
    51001 cagcacggca actttcgggc gcacgccagt ggcaataaac ggtgctgcca catcttcgtt
    51061 gatatcaaac gacagtttca cattcaggcc cggatcggcg tcgtttgatt tcgcctggtg
    51121 ttcctgatcg gcacactccg ggttgtcacg caggcgctgc atctgccagg tagtttctgc
    51181 ccaccagaca cgcagcgtgg tgcggctttc gctaaataca gtctgcccgt tggcagtaat
    51241 cacaaaacgg tcaccggaaa ccgcctgccc aacataatgg acgcaatcag caagcccatg
    51301 ctgtgccagt accgcttcaa cggcttcacg atcagcagct cgaacctgaa tcaccgcacc
    51361 cagttcttcg ttaaacaacg ccgccaggcg atcgtcaccc agagaggcga tatccgcgtc
    51421 aatgccacaa tgaccagcaa aggccatttc cgccagcgtt accagcaggc cgccatcaga
    51481 gcggtcgtga tacgccagca gcttacgctg tgcaaccagc gcctgaatcg cgtcatagaa
    51541 gcctttcagt tgggcaacat cgcgtacatc tgccggtttg tcgccaagct gacgataaac
    51601 ctgcgccagt gccgttgcgc ccagcgcgtt attgcctttg cccaaatcaa tcagcaacag
    51661 tgcgttatct tcggtagaaa gctgcggcgt aatggtgtga cgtacatctt ccacgcgggc
    51721 aaatgcggaa atcaccagcg acaacggcga cgtcatttcg cgctcttcgt taccttcctg
    51781 ccagcgggtt ttcatcgaca tagagtcttt acccaccggt atcgtcaggc ccagcgccgg
    51841 acaaagttct tcgcccacag ctttaacggc ttcatacagg cccgcatctt caccagggtg
    51901 gcctgccgcc gccatccagt tggcggaaag tttaatgcgt ttgatatcgc caatttgtgt
    51961 tgcggcgatg ttggttagcg cttcaccgac tgccagacgg gcagaagcgg cgaaatccag
    52021 cagcgcaact ggcgcacgtt cgccaattgc catcgcttcg ccatagtagc tgtcgaggct
    52081 ggcggtagtg accgcgcagt tagcgaccgg cacctgccac ggccccacca tctgatcgcg
    52141 cgccaccatg ccggttacgc tgcggtcacc gatggtcacc aggaaagttt tctccgccac
    52201 ggtcggcaga tgcagcacgc gtttcaccgc gtcagcgatg gtgatccctt cacgggccag
    52261 cgcgtcgcct ttcgctttca gcgtttgcac atcgcgggtc atcttcggcg ttttgccaag
    52321 cagtacgtcc agcggtagat caatcggctg attatcaaaa tgacgatcgt gcagagaaag
    52381 atgcagttct tcggtcgctt caccaatcac cgcgtacggt gcgcgttcac gcttacacag
    52441 ttcgtcaaac agcggtaact gatcggcagc aactgccagc acgtagcgtt cctgggattc
    52501 gttacaccag atttccagcg ggctcatgcc tggctcgtcg ctcagaatat cgcgcagttc
    52561 gaatttaccg ccgcgcccgc cgtcgctcac cagttccggc atggcgttag aaagaccgcc
    52621 tgcgccaacg tcgtggataa acaggattgg gttggcatca ccaagctgcc agcaacggtc
    52681 gatcacttcc tggcagcgac gctccatctc cgggttgtcg cgctgtacgg aagcaaagtc
    52741 gaggtcggca tcagactgac cagatgccat ggaagacgcc gcgccgccgc caagaccgat
    52801 gttcattgcc gggccgccga gaacgaccag cttcgcacca acgttgatct cgtctttttg
    52861 tacgtgatcg gcgcgaatgt tgccgatccc acccgccagc atgatcggtt tgtgataacc
    52921 gcgcagctct tcgccattgt ggctgttcac tttttcttca taagtacgga agtagccgtt
    52981 cagtgccggg cgaccaaatt cgttgttaaa cgccgcgccg cccagcgggc cttcggtcat
    53041 gatgtccagc gcggtgacaa tgcgctcagg cttaccgaaa tcttcttccc acggctgttc
    53101 aaagcccgga atacgcaagt tggatacgga gaaaccaacc agaccggctt tcggctttgc
    53161 gccgcgcccg gtggcacctt catcgcggat ttcaccgcca gaaccggtcg ccgcacccgg
    53221 ccacggagaa atcgccgtcg ggtggttgtg ggtttcaact ttcatcagaa tatgcgccgg
    53281 ttcctgatgg aaatcgtagc ggcccgtttc gtggtcagca aagtagcgac ccacttcaga
    53341 accttccatt acagcggcgt tatctttata agcagagaga acgtggtctg gcgtggtttc
    53401 gaaggtgttt ttgatcatct tgaacagcga tttcggctgc tgttcaccgt cgataatcca
    53461 gtcggcgtta aaaattttgt gacggcagtg ctcggagttc gcctgcgcga acatatacag
    53521 ctcgatgtcg ttcgggttac gacccagctt tgtgaacgca tcctgcagat agtcaatttc
    53581 atcttccgcc agtgccaggc caagacgcag gttagcgtcg attagcgcct gacggccctg
    53641 ccccagcaaa tctacgctgg tgaccggagt cggttgatgg tgtgcaaaca actgctctgc
    53701 atcatctaaa gcaaaaaaga ccgtttccat catgcggtcg tgcagttcag cggtcacctg
    53761 ctgccattgt tcattggtca gcgtaccggc ttctatatag taagccatgc cgcgctcaag
    53821 gcggtttacc tgttgtagac cgcaattatg ggcgatatcg gtcgctttcg aagaccaggg
    53881 agagatggtg ccaggacgcg gggtcaccag caggagtttg ccttgcgggg cgtggctggc
    53941 gagtgccggg ccatatttca gcaggcgttc aagttgtgcg tgctcatcat cgtttaacgg
    54001 cgcattgagg tcagcaaaat ggacatactc ggcgtaaata gtgtgaaccg ggagcctggc
    54061 agcctgaaaa cgtgccagca gtttgttgat tcggaatgcc gacaatgcag gcgaaccacg
    54121 cagaatttcc atcataagtc tctcgtcttc taagctttcg gtgtacccaa gggggggaaa
    54181 cgggcgtcat tataaagaat ctgatgcgct gacgaaaccg tttgcgtgga aataaaatca
    54241 ccatcgtgaa ttagcaacgc gtgccgccaa tggctgtaat aagttgccat ctggcgcagg
    54301 tttacgcaaa atgccgctca tttatgagta aacctttcac tattattacg ttttttcaag
    54361 ctgggacgcg cacgacacag agaattaact aattgaaaaa attaaagatt aattatctgt
    54421 tcatcggcat tctggcactg ctgctcgcgg tcgctctctg gccatccatt ccctggtttg
    54481 gtaaagccga caaccgtatc gccgccattc aagcgcgggg agagttgcgt gtgagcacca
    54541 ttcatactcc cctgacttat aacgaaatca acgggaaacc ttttggcctg gattacgaac
    54601 tggcgaaaca gtttgccgat tacctcggtg taaaactgaa agtgaccgtg cggcagaata
    54661 tcagccagct gtttgacgac ctcgataatg gtaacgccga cctgctggcg gcaggactgg
    54721 tctataacag tgagcgggta aaaaattatc agcctggtcc tacctattat tccgtgtcac
    54781 aacaactggt ttataaagtg ggtcagtatc gcccacgtac gctgggcaac ctgacggcgg
    54841 agcaactcac cgttgcaccg ggtcacgtgg tggttaacga tctccagacc ctgaaagaca
    54901 caaaattccc ggaattaagc tggaaggtag acgacaaaaa aggctctgcg gaattaatgg
    54961 aagatgtcat cgaaggaaaa ctcgattaca ccattgctga ttctgtcgcc atcagcctgt
    55021 ttcagcgcgt tcacccggaa ctcgccgtag cgctcgatat caccgatgaa caaccggtga
    55081 cctggtttag cccgttagat ggcgataata ccctttccgc cgccctgctc gacttcttca
    55141 acgaaatgaa tgaagacggt acactggcac gcattgaaga gaaatacctg gggcatggcg
    55201 atgattttga ttacgtcgat acgcgcacat ttttacgcgc cgtcgatgcg gtactgccgc
    55261 agttaaagcc cctgtttgag aaatacgccg aagaaattga ctggcgtttg ctggccgcta
    55321 ttgcttatca ggaatcgcac tgggatgcgc aggccacttc accgacgggt gtgcgcggca
    55381 tgatgatgtt aaccaaaaac accgcgcaaa gcctcggcat tacggatcgt accgatgccg
    55441 aacagagcat cagcggcggc gtgcgttatt tacaggatat gatgagtaaa gtgccggaaa
    55501 gtgtgccgga gaacgaacgg atctggtttg ccctcgccgc gtacaatatg ggctatgcgc
    55561 atatgctgga tgcccgcgcc ctgacggcaa aaaccaaagg taatcctgac agttgggctg
    55621 acgtaaaaca gcgtctgcct ttacttagcc agaaacccta ttacagcaag ctgacttacg
    55681 gctacgctcg tgggcatgaa gcctacgctt atgtcgaaaa tattcgtaaa taccagatta
    55741 gcctggtggg ttatctgcag gagaaagaga agcaggctac agaagcggcg atgcaactgg
    55801 cgcaggatta tccggcggta tcgcctacgg agctgggcaa agagaaattt ccttttctct
    55861 cgtttctttc ccagtcgtca tcaaactatt tgacccactc tccctctctg ctgttttcca
    55921 gaaaagggag tgaagagaaa caaaattaat ctgtcgagga ttgcgctttt ttctgcgctt
    55981 taatttcctg gcggcgcatg cgaaagaagt cactgagcaa cgccgcacac tcatccgcca
    56041 gtattccttc cgtaatttcc acccggtgat tcatacccgg atgatgcagc acatccatta
    56101 aagatcccgc agcgccagtt ttcgcgtcac gcgcaccaaa gaccacgcga ccaatgcgac
    56161 tgtggatcat tgctccggca cacattacac agggttcaag cgtgacatac aacgtggcgt
    56221 cgatcagacg ataattttgc atcaccagac cgccctgccg tagggccatg atttctgcat
    56281 gtgcggtggg atcatgtcga ccaatcggac ggttccagcc ttcgccaata acacgattgt
    56341 tatgcactaa taccgcgccg accggtactt cccgctcatc ccaggcacgc ttcgccagcg
    56401 tcattgcatg acgcatccag tattcgtagc taaattcgac ttcagacaaa aagaaaactc
    56461 cggttataaa agcgcggcgc attatacacg gacgctatgc tttactctat tccagttgct
    56521 ggagttcacc gcgcggggtt acccgccagc gatgctggca aaagtaaagc agcgggttgt
    56581 cctggttact gtcgctatag ccactgtaca gccgcagcgg cgtgccgatt ttgcgctcca
    56641 gttgcgcgac cttctcatgc ccgaggcaac gcatcgtcaa tacccaacca ccatagccac
    56701 gctgaatctg actggcgata agattaaccc gcggcagcca gggcgtatcg aaataaaccg
    56761 cttcaaccag cggctgcgga gagccggtaa tcaaccagat atcagcatcg gaacttaaca
    56821 ggtaggtggt taatcgctcc tgaaccagcg gaaaggcggt aacattgtca cgaaaccagc
    56881 gtacgaaatc ggcctgcaac gcctgcaaac gcgcttcatt gtgaccaaaa gtgcatcccc
    56941 acagaagcag actcatcggc cagcgtgccg cacgaccttt tatcaataac gcaatggcta
    57001 tgatcggcaa caacggcaga acaagtaacg cattcagcgg ttggcgacgc agtaaataac
    57061 gcaaaaaact gccgaacata tcctgctgat gcaatgttcc atctaagtca aaaaacacca
    57121 cacgacgctc gtgagttgcc aaaccatact cctctggact gaaacatcct gattaatttt
    57181 cgctactaca tagcctaaca gatagatcat cacttttccg gcaacaatcg accgcatcat
    57241 ggctaactgg aatttttaat tcatggcaat tagcggcaat ggaatataaa attcactcgc
    57301 gtgtgtctca tattgcctgt tgtcgccatt atttcatcgc gaggaaagat atgaacggct
    57361 tacttcgtat ccgtcagcgt taccaggggc ttgcccagag tgataaaaaa ctggcggatt
    57421 atctgctgct acaacctgat acggcgcgcc atttaagctc tcagcaactg gccaacgaag
    57481 ccggagtcag tcagtccagc gtcgtgaagt tcgcgcaaaa actcggctat aaaggttttc
    57541 cggcactaaa gttggcgttg agtgaagcgc tggcaagcca gccggaatct ccctccgtgc
    57601 ccattcataa ccaaatccgc ggtgatgatc cgttacggct ggtcggcgaa aaactgatta
    57661 aagaaaatac tgccgctatg tacgcaacgt taaacgttaa tagtgaagag aaactgcatg
    57721 aatgcgtggc aatgttgcgc tctgcgcggc ggataattct gaccggtatt ggcgcttcgg
    57781 gtctggtggc gcaaaacttt gcctggaagc tgatgaagat tggcttcaat gctgccgcag
    57841 tgcgcgatat gcatgcgcta ctcgctaccg tacaggcgtc gtcccctgac gatctgttat
    57901 tagccatttc ctacaccggt gtacggcgcg agttaaacct ggcggcagat gagatgctgc
    57961 gagtgggcgg aaaagtgctg gcgattaccg gctttactcc caatgccctg caacagcgtg
    58021 cttctcattg cctgtatacc attgccgaag aacaagcgac aaacagtgct tcaatctctg
    58081 cttgtcacgc gcagggaatg ttaacggatt tgctgttcat tgcgctgatt cagcaggatc
    58141 tggaactggc accagaacgt attcgtcata gcgaagcgct ggtgaaaaaa ctggtctgag
    58201 taaagaatgc gcgtataatg cccgcccggt ttgtgttgtt ttgagagttt ccttatggcg
    58261 ctgttaatca ctaaaaaatg catcaattgt gatatgtgtg aacccgaatg cccgaatgag
    58321 gcgatttcga tgggtgaaca tatctacgag attaacagcg ataagtgtac cgaatgcgta
    58381 gggcactacg agacaccaac ctgccagaag gtgtgtccga tccccaatac tattgtgaaa
    58441 gatccgcaac atgtcgagac ggaagaacag ttgtgggata aatttgtgct gatgcaccac
    58501 gcggataaaa tttaatattc tgctctggaa gt
//
LOCUS       DAPOXO010000022        56923 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPOXO010000022 DAPOXO010000000
VERSION     DAPOXO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 56923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56923
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.022"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..369
                     /locus_tag="ROH59_001668"
     CDS             <1..369
                     /locus_tag="ROH59_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418262.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804166.1"
                     /translation="FIPTSKGRISRRRYIFSFIFTNLICILLISFFSNAGAGFFVITS
                     TILLHYLVINMNCQRLRDSGFTYIKTYIFSTLVVYIISFIIMVAEHFDCSGNGSMIFL
                     ICYFSTFGMLVLAPTDSPRK"
     gene            384..764
                     /locus_tag="ROH59_001669"
     CDS             384..764
                     /locus_tag="ROH59_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HDX4804167.1"
                     /translation="MSKDYMADGSLTEKWKYRFSFYDEHGFPGFWGASPEYKQALKGL
                     NTRQKIIIRTNVIAFFFSWVYLFVLGLWKKAIVVLFLAIFSLIFGYMIGYNVFGFIIA
                     AYVSYNTNRWFYEKEVKGIHTWSL"
     gene            complement(807..1757)
                     /gene="corA"
                     /locus_tag="ROH59_001670"
     CDS             complement(807..1757)
                     /gene="corA"
                     /locus_tag="ROH59_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HDX4804168.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            2127..2891
                     /locus_tag="ROH59_001671"
     CDS             2127..2891
                     /locus_tag="ROH59_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HDX4804169.1"
                     /translation="MAHRLFIGKGMITLNLKRIFLTLTLLPLFAVAADDCAPSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADINSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     LLMENGVINPRIHPNVASRKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGEAIPWQRYPFVTMISVEQKG"
     gene            2974..3876
                     /locus_tag="ROH59_001672"
     CDS             2974..3876
                     /locus_tag="ROH59_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HDX4804170.1"
                     /translation="MKKTLATLFLLTCLGSSSAYADNALILQTDFSLKDGAVSAMKGV
                     AFGVDHNLKIFDLTHEIPPYNIWEGAYRLYQTASYWPQGSVFVSVVDPGVGTDRKSVV
                     LKTKNGQYFVSPDNGTLTLVAESLGIESVRQIDEKTNRLKGSEKSYTFHGRDVYAYTG
                     ARLASGAITFEQVGPELPAKVVELSYQKAKATKGEVKGNIPILDIQYGNVWSNISDEL
                     LNQAGIKLNDTLCVTISEGSQQKYAGKMPYVASFGDVPEGQPMVYLNSLLNVSVALNM
                     DNFAQKHQVASGADWNIDVKKCAK"
     gene            complement(3931..6093)
                     /gene="uvrD"
                     /locus_tag="ROH59_001673"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             complement(3931..6093)
                     /gene="uvrD"
                     /locus_tag="ROH59_001673"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HDX4804171.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLETV"
     gene            complement(6177..6893)
                     /gene="yigB"
                     /locus_tag="ROH59_001674"
     CDS             complement(6177..6893)
                     /gene="yigB"
                     /locus_tag="ROH59_001674"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HDX4804172.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            complement(6893..7789)
                     /gene="xerC"
                     /locus_tag="ROH59_001675"
     CDS             complement(6893..7789)
                     /gene="xerC"
                     /locus_tag="ROH59_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDX4804173.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIIHFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            complement(7786..8493)
                     /locus_tag="ROH59_001676"
     CDS             complement(7786..8493)
                     /locus_tag="ROH59_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HDX4804174.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLARWIERV"
     gene            complement(8490..9314)
                     /gene="dapF"
                     /locus_tag="ROH59_001677"
     CDS             complement(8490..9314)
                     /gene="dapF"
                     /locus_tag="ROH59_001677"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDX4804175.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGIGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            complement(9351..9554)
                     /locus_tag="ROH59_001678"
     CDS             complement(9351..9554)
                     /locus_tag="ROH59_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX4804176.1"
                     /translation="MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            9713..9898
                     /locus_tag="ROH59_001679"
                     /pseudo
     CDS             9713..9898
                     /locus_tag="ROH59_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580503.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DKNYY family protein"
     gene            10024..10344
                     /gene="cyaY"
                     /locus_tag="ROH59_001680"
     CDS             10024..10344
                     /gene="cyaY"
                     /locus_tag="ROH59_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HDX4804177.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            complement(10384..12930)
                     /gene="cyaA"
                     /locus_tag="ROH59_001681"
     CDS             complement(10384..12930)
                     /gene="cyaA"
                     /locus_tag="ROH59_001681"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HDX4804178.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQEHDAPLLQQYFS"
     gene            13317..14258
                     /gene="hemC"
                     /locus_tag="ROH59_001682"
     CDS             13317..14258
                     /gene="hemC"
                     /locus_tag="ROH59_001682"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDX4804179.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDARTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSLIIRGER
                     RGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            14255..14995
                     /gene="hemD"
                     /locus_tag="ROH59_001683"
     CDS             14255..14995
                     /gene="hemD"
                     /locus_tag="ROH59_001683"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HDX4804180.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGRQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPTYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKCALILRGNGGRELIGDSLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQSREVTTVVVTSGEMLQQLWSLIPQWYREHWLLRCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            15017..16216
                     /gene="hemX"
                     /locus_tag="ROH59_001684"
     CDS             15017..16216
                     /gene="hemX"
                     /locus_tag="ROH59_001684"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDX4804181.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     AIALAAGVGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAVQLE
                     QANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRL
                     ADNDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFITIRRRDDTAVPLLAPNQD
                     IYLRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQL
                     SQQNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPAPAPAPQADAP
                     AAAPQGE"
     gene            16219..17415
                     /gene="hemY"
                     /locus_tag="ROH59_001685"
     CDS             16219..17415
                     /gene="hemY"
                     /locus_tag="ROH59_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HDX4804182.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTL
                     QNNPPQ"
     gene            17465..18055
                     /locus_tag="ROH59_001686"
     CDS             17465..18055
                     /locus_tag="ROH59_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804183.1"
                     /translation="MRTPSRYIFRLPSHEINPFRATLLLILLICAVLAGVSWLILSFV
                     RTGNTFIFWLTLFIGYLIAIAKQEKIKLIEKRQIMADKRQGLSICQFARQFSPHTVDT
                     WVIRAVWNTLQGNGYIDYPLPLKASDKLDDDLDLVNDADELEELVEDIAARCGRDLRG
                     IEDNPFLPITTVGSLVSVLNAQPMTQERRSLLFTRS"
     gene            18685..20340
                     /gene="aslA"
                     /locus_tag="ROH59_001687"
     CDS             18685..20340
                     /gene="aslA"
                     /locus_tag="ROH59_001687"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase AslA"
                     /protein_id="HDX4804184.1"
                     /translation="MEFSFSPKLLVVAVAAALPLIASAADTPSTATARKGFAGYDHPN
                     QYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVG
                     FNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMY
                     GQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYT
                     EWRDVHVNPEVALSPDRSEYIQKLPFSKDDVHAVRGGEQEAIADITPKYMEDLDQRWM
                     EYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDIFA
                     NLYKALEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWK
                     GMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQS
                     NRKAEHYFLNGKLSAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLY
                     TDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD"
     gene            complement(20431..21666)
                     /locus_tag="ROH59_001688"
     CDS             complement(20431..21666)
                     /locus_tag="ROH59_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HDX4804185.1"
                     /translation="MQQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYHEKPVTH
                     MDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISN
                     SFQTNGVLLDDEWCGFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
                     QKHHVDYNVLVCVNRTSALQPLQVYDFLCDAGVEFIQFIPVVERLANETAAHAGLKLH
                     APGDIQGELTEWSVCPQEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMLQQMIAEMIDSPQQQAFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPELNYLCAGYQRYFRHLPPYLKAMVDLL
                     AHGRPASDIMQAHLLVVNK"
     gene            complement(21813..21889)
                     /locus_tag="ROH59_001689"
     tRNA            complement(21813..21889)
                     /locus_tag="ROH59_001689"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21853..21855),aa:Pro,seq:tgg)
     gene            complement(21932..22018)
                     /locus_tag="ROH59_001690"
     tRNA            complement(21932..22018)
                     /locus_tag="ROH59_001690"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21982..21984),aa:Leu,seq:cag)
     gene            complement(22039..22114)
                     /locus_tag="ROH59_001691"
     tRNA            complement(22039..22114)
                     /locus_tag="ROH59_001691"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22079..22081),aa:His,seq:gtg)
     gene            complement(22173..22249)
                     /locus_tag="ROH59_001692"
     tRNA            complement(22173..22249)
                     /locus_tag="ROH59_001692"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22213..22215),aa:Arg,seq:ccg)
     gene            complement(22352..23737)
                     /locus_tag="ROH59_001693"
     CDS             complement(22352..23737)
                     /locus_tag="ROH59_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX4804186.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLTVTAIYKVFGL
                     NRHGKAHKLEE"
     gene            complement(23928..24668)
                     /gene="rffM"
                     /locus_tag="ROH59_001694"
     CDS             complement(23928..24668)
                     /gene="rffM"
                     /locus_tag="ROH59_001694"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HDX4804187.1"
                     /translation="MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(24671..26023)
                     /gene="wzyE"
                     /locus_tag="ROH59_001695"
     CDS             complement(24671..26023)
                     /gene="wzyE"
                     /locus_tag="ROH59_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HDX4804188.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGAAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
                     "
     gene            complement(26020..27099)
                     /gene="rffT"
                     /locus_tag="ROH59_001696"
                     /gene_synonym="wecF"
     CDS             complement(26020..27099)
                     /gene="rffT"
                     /locus_tag="ROH59_001696"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HDX4804189.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPS
                     QFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
                     LYFPTRMDPSLNMMANDRQREGKMTILVGNSGDRSNEHIAALRAVYQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQTLSEKLEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLVSVDKN
                     TIAFFSPNYLQGWQRALAIAAGEVA"
     gene            complement(27096..28346)
                     /gene="wzxE"
                     /locus_tag="ROH59_001697"
     CDS             complement(27096..28346)
                     /gene="wzxE"
                     /locus_tag="ROH59_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HDX4804190.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSTLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEVSQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(28348..29478)
                     /gene="rffA"
                     /locus_tag="ROH59_001698"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(28348..29478)
                     /gene="rffA"
                     /locus_tag="ROH59_001698"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HDX4804191.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNINETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKNGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGEHFG
                     EFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(29483..30157)
                     /gene="rffC"
                     /locus_tag="ROH59_001699"
                     /gene_synonym="wecD"
     CDS             complement(29483..30157)
                     /gene="rffC"
                     /locus_tag="ROH59_001699"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HDX4804192.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRISPDAALLTPDALAPWSRV
                     QAKIAASNTGELDALQQLGFSLIEGEVDLALPVNNVSDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASGRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
                     TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(30135..31016)
                     /gene="rfbA"
                     /locus_tag="ROH59_001700"
     CDS             complement(30135..31016)
                     /gene="rfbA"
                     /locus_tag="ROH59_001700"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDX4804193.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(31035..32102)
                     /gene="rffG"
                     /locus_tag="ROH59_001701"
     CDS             complement(31035..32102)
                     /gene="rffG"
                     /locus_tag="ROH59_001701"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDX4804194.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVVVVDTLTYAGNLMSL
                     APVAQSERFAFEKVDICDRAELARVFTEYQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWTALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKPLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVAHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     ESWWKQVQDGSYQGERLGLKG"
     gene            complement(32102..33364)
                     /gene="wecC"
                     /locus_tag="ROH59_001702"
     CDS             complement(32102..33364)
                     /gene="wecC"
                     /locus_tag="ROH59_001702"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HDX4804195.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGELADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRANELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(33361..34491)
                     /gene="wecB"
                     /locus_tag="ROH59_001703"
     CDS             complement(33361..34491)
                     /gene="wecB"
                     /locus_tag="ROH59_001703"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDX4804196.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(34547..35593)
                     /gene="wzzE"
                     /locus_tag="ROH59_001704"
     CDS             complement(34547..35593)
                     /gene="wzzE"
                     /locus_tag="ROH59_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HDX4804197.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIVFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(35605..36708)
                     /gene="wecA"
                     /locus_tag="ROH59_001705"
     CDS             complement(35605..36708)
                     /gene="wecA"
                     /locus_tag="ROH59_001705"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HDX4804198.1"
                     /translation="MNLLTVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGKLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(36948..38207)
                     /gene="rho"
                     /locus_tag="ROH59_001706"
     CDS             complement(36948..38207)
                     /gene="rho"
                     /locus_tag="ROH59_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDX4804199.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(38292..38393)
                     /gene="rhoL"
                     /locus_tag="ROH59_001707"
     CDS             complement(38292..38393)
                     /gene="rhoL"
                     /locus_tag="ROH59_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide RhoL"
                     /protein_id="HDX4804200.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(38534..38863)
                     /gene="trxA"
                     /locus_tag="ROH59_001708"
     CDS             complement(38534..38863)
                     /gene="trxA"
                     /locus_tag="ROH59_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HDX4804201.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            38994..40259
                     /gene="rhlB"
                     /locus_tag="ROH59_001709"
     CDS             38994..40259
                     /gene="rhlB"
                     /locus_tag="ROH59_001709"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HDX4804202.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            40395..41879
                     /gene="gppA"
                     /locus_tag="ROH59_001710"
     CDS             40395..41879
                     /gene="gppA"
                     /locus_tag="ROH59_001710"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HDX4804203.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPPQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLTVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFEQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFANRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIDQESQWQSYVHWPLEVH"
     gene            complement(41926..43947)
                     /gene="rep"
                     /locus_tag="ROH59_001711"
     CDS             complement(41926..43947)
                     /gene="rep"
                     /locus_tag="ROH59_001711"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HDX4804204.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAEAKGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGTELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            44034..44315
                     /gene="ppiC"
                     /locus_tag="ROH59_001712"
     CDS             44034..44315
                     /gene="ppiC"
                     /locus_tag="ROH59_001712"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HDX4804205.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     gene            complement(44361..45836)
                     /gene="ilvC"
                     /locus_tag="ROH59_001713"
     CDS             complement(44361..45836)
                     /gene="ilvC"
                     /locus_tag="ROH59_001713"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDX4804206.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     VNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            45986..46876
                     /gene="ilvY"
                     /locus_tag="ROH59_001714"
     CDS             45986..46876
                     /gene="ilvY"
                     /locus_tag="ROH59_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HDX4804207.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEDDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSADKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCV
                     QKKRLHEPLIEAFWKILPNH"
     gene            complement(46873..48417)
                     /gene="ilvA"
                     /locus_tag="ROH59_001715"
     CDS             complement(46873..48417)
                     /gene="ilvA"
                     /locus_tag="ROH59_001715"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HDX4804208.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIAQHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTHWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(48420..50270)
                     /gene="ilvD"
                     /locus_tag="ROH59_001716"
     CDS             complement(48420..50270)
                     /gene="ilvD"
                     /locus_tag="ROH59_001716"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDX4804209.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQDDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDIIVTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDTLDDDRSNGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQEARGNKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(50335..51264)
                     /gene="ilvE"
                     /locus_tag="ROH59_001717"
     CDS             complement(50335..51264)
                     /gene="ilvE"
                     /locus_tag="ROH59_001717"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HDX4804210.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(51284..51547)
                     /gene="ilvM"
                     /locus_tag="ROH59_001718"
     CDS             complement(51284..51547)
                     /gene="ilvM"
                     /locus_tag="ROH59_001718"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HDX4804211.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(51544..53190)
                     /locus_tag="ROH59_001719"
     CDS             complement(51544..53190)
                     /locus_tag="ROH59_001719"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HDX4804212.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDILGLSLACTKHSFLVQSLEELPRIMAEAFDVASSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVSALRE
                     FLAATKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDPAEMNKLRQAHVALQGDLNALLPALQQPLNIDDWQQHC
                     AQLRDEHAWRYDHPGDAIYAPLLLKQLSDRKPADCIVTTDVGQHQMWAAQHIVHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITHKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(53193..53243)
                     /locus_tag="ROH59_001720"
     CDS             complement(53193..53243)
                     /locus_tag="ROH59_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804213.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(53330..53428)
                     /gene="ilvL"
                     /locus_tag="ROH59_001721"
     CDS             complement(53330..53428)
                     /gene="ilvL"
                     /locus_tag="ROH59_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HDX4804214.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            53781..55301
                     /locus_tag="ROH59_001722"
     CDS             53781..55301
                     /locus_tag="ROH59_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312727.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDX4804215.1"
                     /translation="MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKE
                     ARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGRYDLPIAIALLAASEQLTANKLD
                     EYELVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLIADHL
                     QAVCAFLEGKHALEHPKPTNAVSRALQHDLSDVVGQEQGKRGLEITAAGGHNLLLIGP
                     PGTGKTMLASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLT
                     AMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITY
                     PARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGI
                     LSKTVVPGENSTTVKQRVMAARERQFKRQNKLNAWLDNPEIRQFCKLESEDAQWLEET
                     LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAVSYRAIDRLLIHLQKLLT"
     gene            complement(55326..55664)
                     /gene="maoP"
                     /locus_tag="ROH59_001723"
     CDS             complement(55326..55664)
                     /gene="maoP"
                     /locus_tag="ROH59_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HDX4804216.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            55783..56622
                     /gene="hdfR"
                     /locus_tag="ROH59_001724"
     CDS             55783..56622
                     /gene="hdfR"
                     /locus_tag="ROH59_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HDX4804217.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLD
                     EVY"
     gene            complement(56718..56793)
                     /locus_tag="ROH59_001725"
     tRNA            complement(56718..56793)
                     /locus_tag="ROH59_001725"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56758..56760),aa:Trp,seq:cca)
     gene            complement(56802..56878)
                     /locus_tag="ROH59_001726"
     tRNA            complement(56802..56878)
                     /locus_tag="ROH59_001726"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56842..56844),aa:Asp,seq:gtc)
BASE COUNT        13913 a        15345 c        14453 g        13212 t
ORIGIN      
        1 tttattccaa catctaaagg cagaatttcc agacgccgct atatattttc atttattttt
       61 acaaatctaa tttgtatctt acttatttct tttttttcca atgccggggc tggtttcttt
      121 gttataacat ctaccattct tttacattat ctcgttatca acatgaattg ccaacgactc
      181 cgggatagtg gttttactta tataaaaact tatattttta gtacattagt agtctatatc
      241 atttctttca tcatcatggt tgctgagcat tttgactgtt ctggcaatgg ttcgatgatt
      301 tttttgattt gttatttttc cacctttggc atgttagttc ttgcccccac tgattccccc
      361 cgtaaataat taatggagat tttatgagta aggattatat ggcagatggc tcattaactg
      421 aaaagtggaa gtaccgcttt tcgttttatg atgaacatgg cttccctgga ttttggggtg
      481 caagcccaga atataaacaa gcattaaaag gattaaacac aaggcaaaag ataataatta
      541 gaacaaatgt tattgctttt ttcttctcgt gggtctattt atttgtattg ggtttatgga
      601 agaaggctat tgttgttcta ttcctggcga tattttcttt aatttttggt tacatgattg
      661 gctataatgt atttggattc attatcgccg cttatgtttc atacaatacc aacagatggt
      721 tctatgaaaa agaagtaaaa ggtattcata cctggagcct ttaaataatc ggtggcttag
      781 ccaggctaag ccaccgttct cgttttttac agccagttct tccgcttaaa gtacagatac
      841 ggtgccaggc ccgcgaggat cataaagata atcgcgcctg ggtagccgaa gctccacttc
      901 agttccggca taaactcaaa gttcatcccg tagctggaag cgaccagcgt cggtggcagg
      961 aacaccacgg ataccaccga gaagattttg atgatgcggt tctgctcgat attgataaag
     1021 cccatcgccg cctgcatcag gaagttcacc ttctggaaca gggattcgtt atgcggcagc
     1081 agggattcga tatctcgcag gatttcacgc gcctgctcca gttgcccacc cggtaagcgt
     1141 gctttacgta ccaggaagtt gagcgcgcgc tgggtatcca tcagacacag gcgaactttc
     1201 cagccgatat cttccagttc cgccagcgtg gagagcgcct cgtcgtactc atcgccctga
     1261 tgcccttcca taattacccg gctcaactgc tccaggtcgc tgtagatatt ttcaatttca
     1321 tctgccaact gttcgatttt ggtttcgaac agatccagca gcagctcgta ggcgttaccg
     1381 tccaccattg actggctacg ggcacgcata cgatacagac gaaaagcggg cagttcacgc
     1441 tcacgcagag taaacagacg accatcacgg atggtaaatg ccacagtgga gttaccggcg
     1501 tgatcttccg catcttcaaa gaagaagaag gagtgaatat gcaggccgtc atcgtcttca
     1561 aagaaacgtg ccgatgcttc gatgtcttcc agttccgggc gggttgccag gctctggcca
     1621 agttcagatt gtacgcgcag tcgctcgtcg tcgtccggtt cgacaagatc aatccatact
     1681 gcatttacaa ggggttgtga ctcttcgact tccagccggg tcagtcggtt attttccagt
     1741 tgaaatgcgc tcagcatgac cgggactccc aatgcttaaa atatcggaca gttcggtggg
     1801 cacacagaaa caaattgggt ttcagaccat taaacagcct gactcagcgc gacgggaaaa
     1861 attgaggtcg ctgacaaccg ctaaggctat cagcaaaaag ggatagcctt aggagttgat
     1921 cctggatgac aggatagtga gccagtatct actgggtgtg tccaaggcga atgtcctctt
     1981 agagtgatcg tgcgcgcatg ttacgccagc aaaattttgc cgtcaacacg caacagaaca
     2041 ccacagaaca atagttgaac ttcgcgcttt ttggtactcg tcaaggtcgc taacaggata
     2101 aaaaaatccc acattcaggg cctataatgg cgcatcggct attcattggt aaaggaatga
     2161 tcaccttgaa tctcaaacgg atttttctca ccctcacctt acttcccttg tttgctgttg
     2221 ccgctgatga ttgcgcaccc tcagatccga cgctgaccgt acaggcgtat accgttaatc
     2281 ctcaaacaga gcgggtgaaa atgtactggc aaaaagccaa tggcgaagcg tggggaacgt
     2341 tacatgcgct gctggcggat attaatagtc agggtcaggt gcagatggcg atgaacggcg
     2401 gcatctatga tgaaagctat gcgccgctcg gtttgtacat cgaaaacggt cagcagaagg
     2461 tggcgttaaa tctcgcttca ggtgaaggga atttctttat tcgccctggc ggcgtgtttt
     2521 atgtcgcggg agataaagtc ggcatcgttc gtctggatgc ctttaaaacc agtaaagaga
     2581 ttcagtttgc ggtgcagtca gggccattgt tgatggaaaa cggtgtaatt aatccgcgta
     2641 ttcatcccaa cgttgcctca cgtaaaattc gtaacggtgt tgggattaat aaacatggga
     2701 acgccgtgtt tttgctgagc cagcaggcga caaattttta tgattttgcc tgttatgcca
     2761 aagcgaaact gaacgttgag cagctgcttt atcttgatgg cacaatttca catatgtata
     2821 tgaaaggcga ggcaatcccg tggcaacgct atccttttgt caccatgatt tccgtcgagc
     2881 agaaaggtta aacattgtac actcgaggag gccagacaaa ctggggctgg ctacacagct
     2941 ggaaaatcat cagataaatg aagggaaaca aaaatgaaaa aaacgctcgc aacattattt
     3001 ttattaacct gtctggggtc atcatccgct tatgcggata acgctttgat tttacaaacg
     3061 gattttagcc tgaaagatgg tgccgtctcg gcgatgaaag gggtcgcatt cggtgttgac
     3121 cataatctta aaatctttga tttaacacac gaaattccac cgtataacat ctgggaaggc
     3181 gcttatcgcc tgtatcagac tgccagttac tggccgcaag gttcggtgtt tgttagcgtg
     3241 gtcgatccag gtgttggtac agaccgtaaa tcggtagtgc tgaaaaccaa aaacggtcag
     3301 tacttcgttt caccagataa cggtacgctc acgttggtgg cggaatcgct gggtattgag
     3361 agcgtccggc aaatcgatga aaaaaccaac cgtctgaaag gttccgaaaa gtcatatacc
     3421 ttccatggtc gtgatgtata tgcctacacc ggtgcgcgtc tggcttccgg ggcgatcacg
     3481 ttcgagcagg tggggccaga gcttcctgca aaagttgtcg aactttctta tcagaaagcc
     3541 aaagcaacaa aaggtgaagt gaagggcaat atcccgattc tcgatattca gtacggcaac
     3601 gtctggagca atatcagcga cgagttgctg aatcaggcag gaatcaaact caacgacacg
     3661 ttgtgtgtga ccatttccga aggttcccag caaaaatacg cagggaaaat gccgtatgtc
     3721 gcaagcttcg gcgatgtgcc ggaaggccag ccgatggtgt atctgaacag cttattgaat
     3781 gtttccgtgg cgctgaatat ggataatttc gcgcagaaac atcaggttgc gtctggtgct
     3841 gactggaata ttgatgtgaa gaagtgcgct aagtaaggtg ctgatgccgg atgcggtgta
     3901 gcgcaccgca tccggcaacg gaatcgtaaa ttacaccgtc tccagtcggg cgtaagccgc
     3961 caccagccat ttaataccct ggccctggaa tgccacctgc aaacggctat gctcgccgct
     4021 gccttccata ttgacgatgg tgccttcacc aaacttagcg tggcgtacgc gctggccgag
     4081 cttgtagccg ctgtcgttct cgaccatcgg cgtccccata cgctgatggc tgaccgggcg
     4141 gcttaccgtg gcgcgcaggc gcacctcttc cacacactct tccggcaact caccgataaa
     4201 gcgcgacggg cgatggtaaa cctctttgcc atatagacgg cgggtttccg cgtaggtcag
     4261 cgtcagtttc tgcatcgcgc gggttacgcc aacgtaggcc agacggcgtt cttcttccag
     4321 acgcccgcct tcatctagcg acatctggct tgggaacatg ccctcttcca taccaacgat
     4381 aaacacctgc gggaattcca gacctttcgc cgagtgtagc gtcatcaact gcaccgcgtc
     4441 ctgccaggta tccgcctgcc cctcgcccgc ttccagcgcc gcatgggaga ggaatgcctg
     4501 cagcggcatt aaatcttcgt cttcttcgtt gtagctgaac tggcgcgttg ccgtcaccag
     4561 ttcctctaag ttttcgatac gcgtctgacc tttttcgccc ttctcctgct cgtacatggt
     4621 gcgcaggccg gagtctttaa ttacccggtc agtctgtaca tgcagcggca tatcggcagt
     4681 ttcctgcgct aaggcgtcga tcagctccat aaaccgctgt aaggcgctgg cagcacgtcc
     4741 ggcgagggct ttttcctgca acagttcacg acatgcctgc cagagtgtta actggcgatc
     4801 tcgcgatgtc tgacgtacca cgtccagcgt ccggtcacca ataccccgcg ttggcgtatt
     4861 caccacacgc tcaaaggccg cgtcgtcgtt gcggttggca atcaggcgca gatacgagag
     4921 cgcatctttg atttcctggc gttcgaagaa gcgcatcccg ccgtaaatac gatacggcat
     4981 actcgcctgc aataacgcct cttccagcac acgcgactgg gcgttgctgc ggtagagaat
     5041 ggcgcactca gcgagcgccc cgccgttgtc ctgccaggtt ttgatgcgat taaccacaaa
     5101 acgcgcttcg tcgagttcgt taaaagcgca ataaagggaa atcggctcac cgtccgcgcc
     5161 atcggtccac agttttttac ccaaacgccc gttgttgttt tcaatcaggg cgttcgcggc
     5221 gctcagaata ttgctggtag agcggtagtt ctgctccaga cggatagttt cagcaccggg
     5281 gaaatcattg aggaaacgct gaatattctc cacctgcgct ccgcgccagc cgtagattga
     5341 ctgatcgtca tcgccaacga tcatcacttt gccggtatcg cccgccagca ggcggatcca
     5401 cgcatactga atgttgttgg tatcctggaa ttcgtccacc aggatattgg taaaccgttc
     5461 gcgatagtgc tgaaggatat gcggcttgtt aagccacaac tcgtgagcac gtagcagcag
     5521 ctcggcgaag tccaccaggc ccgcgcggtc acacgcttcc tgatacgcct gatacacctt
     5581 ctgccaggtc tgctccaccg gattaccgta gctctgaata tgatgcggac gcagcccctc
     5641 atctttctgg ctgttgatgt accacattgc ctgacgcggc ggccactgct tctcgtcgag
     5701 attcatcgcc ttgatcaaac gcttaagcag acgtagctgg tcttcactgt cgaggatctg
     5761 gaaatcctgc ggcaggttgg cgtccatatg gtgcgcacgc agcaggcggt gcgccagccc
     5821 gtggaaggtg ccgacccaca taccgccctg gctagtgccc atcagttgcc cgatacgatg
     5881 acgcatctcc gccgccgctt tgttggtaaa cgtcaccgcc ataatcgaat acggcgagca
     5941 gttttccacg ctcatcaacc aggcgatacg atgcaccagt acgcgcgtct taccactgcc
     6001 cgcgcccgcc agcaccagaa ggttgctgcg tggcgcggcc accgcttcgc gctgtttgtc
     6061 attaaggctg tcgagcaggt aagaaacgtc cattggcacc gccgcgtaaa aataggttgg
     6121 gcggagaagc gcaacgccct ccgccaaaaa gctgggtata tatacagatt tgctgattat
     6181 atcagcgagg tcagagatgc caaccgggaa atttccagat gcggcagtaa acggctgtcc
     6241 caggtttgca tcagatcgcc attttccggt ctgatccaac aggcctgcat tccgctgcga
     6301 attgccccac ccacgtcagt ggtgagatcg tccccgacat gtaagatctc gccgatcggc
     6361 acgttgagtt tttccgccgc caggaagtac atatcgctga acggttttga gcgcccgtgc
     6421 gggccagcgc gcagcacaaa ctcaaaataa tcccccaaac caaacagttc cggctgggcg
     6481 ttaccgttgg tgatcgccac cagcggccat ttcttcgcca gctgttttaa ggtgtcgtgg
     6541 gtttgctgcg ggacgtcgat ccggctgcgc catttggcaa agttgatcat tgctgcatgt
     6601 gcgcctgcac tggcttcttc ggcactcagc ccggcgtcga gcatcgcttg ttcaatcgaa
     6661 cgaaaacgcc agcgcgtcac gtcgtgataa atctcaggtt ccgcttcccg taccgcctgg
     6721 cgcaggcgtt gcagatcttc attctggaag ctgcgcagcg ccggatgata attttgcaca
     6781 aaggtaagcg cctctcgctc ggtgcgcaaa atcaccggac ggttatcgta aagggtatca
     6841 tccaggtcaa aggtgagcgc cgagatgcgc cccaaaggcc ggtaaaaacg cattatttcc
     6901 cccgtttggc gcgtggatgc gccgcatcgt acaccgaggc aaggtgttga aaatcaagat
     6961 gagtatagat ttgcgtggtg gagaggttgg catgacccag cagctcctgc acaccacgaa
     7021 gatcgccgct cgactccagc atatgggtag cgaacgagtg acgtaattta tgcgggtgaa
     7081 cgtgattatt cagcccttgt tttatgcccc attcggcaaa gcgtttctgc acattacgcg
     7141 cggagatgcg tttgcccagt ttcgacagaa aaagcgcgtc gtcttcgcta ccaaacaggt
     7201 cgcgcaaatc aagccagtgc tcaatccacg ccacggcgtt gcgaccaatc ggcaggcggc
     7261 gctctttgct gccttttccc atcacccaca cttcgccaga ctccaggtcg aggtgtttga
     7321 tatcgagccc caccagctcg gaaagacgca gacccgcgcc gtacatcact tccagcattg
     7381 cccgatcgcg cacggcgagg ggatcgttga tatcaatatc cagcagccga ttcatatcat
     7441 cgacgtcgat gtttttcggc agatgacgcg gcgctttcgg tgccgaaaca cctttcgccg
     7501 ggttagcttt gagttcattc tggctgacca gccagtcaaa aaagctacgt agcgcagaaa
     7561 gccgtaacgc cagacttgca gctcccagcc ctttacggcg actgcgtaca gcaaaattac
     7621 gcaccatcgt cacatcacat tgctgccagc tttgcaggcc gttttcgctg gcaaaatgga
     7681 tgatcgcctc aagctgtcgc tggtagttaa gcagggttat cgggctaagc tggcgctcca
     7741 cgctcagata acgtaggtag cgttctacat cggtgtgtaa atcggtcata cgcgttcaat
     7801 ccaacgcgcc agaagctccg gcaacatcag cgcaatttca tgaagtaact gcgttccctg
     7861 cccttgttga tagtgactgg catcgcgact ggtaaacagc acaaccccca aatcagcatc
     7921 gcttcccagc atcgacatcg ccaccgatcc caccgctttc gcttccggta gcaccaccag
     7981 cagctccggt ccgttaagcg gtcccagata gtgctgttcc tgccccagac gctgaatacg
     8041 cagcggttcg aaagactgac ggcttaatgc cagatgagtg tggttcgacg gcgcacctaa
     8101 gcgccagcga tctggaaaca ggcgcagact cgcacctgcc aggccgagat cgcgcgccca
     8161 gcggtgaaag cgcatcagca tatcatcgag actgctggcg gcggtgagac tgcgctgcag
     8221 gtagagtaga cgataaaaca ggccttcgtt ggcgatagcc tgttccatca acaacgccat
     8281 gttctcttcc agaacatgaa tatgattacg tgcgcgggcc atgtgccact cgaccaacga
     8341 aacggtgccg cgtaccggat gcggcacacg tatcgcttct actgcgcgcg cattgcggat
     8401 aaaaaactca ggatttttaa tcagataatc gacaaccgcc cggtcatcaa gctccgtgag
     8461 tgtttcctgc agttcttccc ctggttgctt catagatgaa taaatccgtc gtagacatgt
     8521 accgccgggc cagtcatata taacgggtga cccggacctt tccaggcgat atcaagacga
     8581 ccgccaggga gttccacgcg tacttcttcg gccagcaaac cttgctgaat ccctaccgcc
     8641 accgccgcac acgcgccgct gccgcaggcc tgggtttctc ctgccccacg ctcataaacg
     8701 cgtaaacgaa tatgctcgcg cttaaccact tgcataaaac cgatattggc gcgctccgga
     8761 aaacgttcgt ggctttccag aacaggacca agcgtttcta ccgccgcagt atcaacatca
     8821 tcaacctgaa tcacgcagtg cggatttccc atcgacacca cgccgcataa gattgtctgc
     8881 tcggcggcgc gcataatata ggtcttttcc gctttgttag cgcgaaatgg cacggcagaa
     8941 ggttcgaagt tgggttcgcc catattgacg cggaccagat catcatcggt gacggtcaac
     9001 accatccgtc cgttggcggt gctgacgcgg atatcgcgct tattggtcag ccctttcagg
     9061 cgcacaaaac gggcaaagca gcgcgcaccg ttgccgcact gcgctacttc actgccatca
     9121 gcattgaaaa tgcgatagtg aaaatccagt tccggatcat acggtggctc aaccaccagc
     9181 agctggtcaa accctatccc caggtgccga tccgccaggc gacgaatcag ctccggtgaa
     9241 aaaaagacat tctgcgttac cgcgtcgacg accataaaat cgttgccaag gccatgcatt
     9301 ttcgagaact gcatcattta ctccaatcac gcgggtacag aaactgactt ttagtaattc
     9361 acctgggatg gaccatcgcc agtggcgcgg tcgtttttgt ccggcaccgt ggattgcgtt
     9421 tgcgtctcta ccggtttggt cggcggcggt gcgtttttat ctgcaggcgg gaaatagagc
     9481 ggacctttca gaccgcagcc cgtcaggctg aagagagtaa gtaatacagt gagtgcctta
     9541 aacacgtttt tcattatgga ttgcctgtaa agttcatcgc tttctgcttt ctatcatcgc
     9601 aggagaaggc gtaaaagcaa gcgtttagcg actctttatg aagtctgaaa agtgaggaaa
     9661 tgctgcgagt ataacgctta ctcgtggcga tttatgtttt gctggtagtt tcgtgatcgg
     9721 cacctcgcgc caggatggct ttatgcacta tcgcaatgtg gtttgtttat tgtcttgttc
     9781 gttgttctta tcatcggcat ggggatgtcg gcttgatgag ccggaacata atatttacca
     9841 gaaacaggga aaaggcgtgg tgtatttgcg cccttatgaa aagaccaatc tttcgctata
     9901 tagagatatt attattccgg tgacggatga atcatgccgg aacgcagcag cagacgggca
     9961 aactttgaag ccctgacccc atgccgctat actgccgcca tcacttaaaa acaggataca
    10021 acaatgaacg acagtgaatt tcatcgcctg gctgatcaac tgtggctgac cattgaagaa
    10081 cgtctggacg actgggatgg cgacagcgat atcgactgtg aaatcaacgg cggtgtacta
    10141 accattacct ttgagaacgg cagcaaaatc attatcaacc gccaggaacc actgcaccag
    10201 gtatggctgg caaccaaaca gggcggctac cattttgatc tgaaaggcga tgagtggatt
    10261 tgcgatcgca gcggcgaaac cttctgggat ttgctggaac aggcggcgac gcagcaggcg
    10321 ggagaaaccg tcagttttcg ttaagagcta atgccggata agcctcgctt tccggcatta
    10381 gcatcaagaa aaatactgct gcaacagcgg cgcgtcatgc tcctgattgg caggtggcat
    10441 gttaccgata gatttggtgc gaaacggaat cacctgttca cgaccatcaa ccttcacaat
    10501 ctgatagaac tgcggcaggt tgaagttgat gaagcttgag ccgtaggtga aacggtcgtg
    10561 cgaagacgag tagaagcgac tgacgtcacg caccagttcc tctttgctgc cttcgcagtg
    10621 gtgatacacc tcaacccggt tgctttcgtc gagaatgtag atattaaagc cattctcgtc
    10681 ttgcgtttct tcgaagaaga actggatgat cccttcgctg gcaaagccgt ccaccaccgc
    10741 cggtaatttg acgtgattgg tttcaacctg cactgacagg ccgtgcagtt tgttatgcga
    10801 aatagcgcca taaaactcga tggcgttttc cagtttctgt accgatacat tcagccgttc
    10861 gaagaacaag ccccaggttt gaccggagac gcgcagcgcc ttgaagcgcc cggtttcctg
    10921 gcgggtgctg gaaagacgca gttcaataca ctcagaaacc agttgctgca cgcgagtacg
    10981 gattaacccg cgcagatgct ggctataaca gaagacttcc acgctatctg gcggtgcggc
    11041 gtcctgatgc attttgccga gaatagtttt cagggcttcg atcatcgatt gctcgccgtt
    11101 gaagtgcagc gtacgcactt cgttccacga gttgcgatac agcaggtcaa cgctacccac
    11161 caggcaattt tgattctcgc caaagctgaa gacatccagc ttacggaaat caaaatgcac
    11221 cacctgattg cggaaggctg ccgtcgggtc atattccagg ttaacgataa tcgccagatg
    11281 gcggatctca cacgggctgt agagcgcctt cggtgtcggt gcaggtaagc gcagcgggaa
    11341 atggtgcgac acgtctgcga ccatctcctg caacttaggc aaatcgacaa tgccgttacc
    11401 tttaatatac aaacgggtgc gagaggtcag caggccgtta aaccatgccc acgccaccag
    11461 tttattcagg tagcgattat attccagcgg ctgatggctg atgattgact caatatttgg
    11521 cgcgcggtta tacagatacc aacctgaacg gttggcgcgg cccggcggta cataaataaa
    11581 ggtcagattc ggttccgaga gatcgggcga aatctgcggg tttaccagcg tcactttacc
    11641 cggtaatgct tcaaacgcgg cgtacagttt acgtgtcagc acgccgatat cctgcgggct
    11701 ggcggagacg ctaaggttat tgcggcgcgc aaagcggatc agattacggt agctctgcat
    11761 cattgcgtcg agcagctcgt tgtgcgcctc acgcacctga tctatcttcc agttagcgcg
    11821 gttatcgagc attgccagac gagcttcgtc ccaaccccac tcgctcacta actggctcaa
    11881 cactgcgcga cgccagccta cacaggcgcg ttcacggctg agcttttcgc acacttttaa
    11941 atagaagcag cgacgcacta aatccagacg ggtgaaatct tcaatcgccg tcaggtattc
    12001 agtaacacgc tccagcatca tgcagtacgg gtcgaggcca aacgatacaa tctcgccgtc
    12061 gtgcaaacgc tgtttgatat ctttcgccag cagacgtggg ttcgggtatt cccaggaata
    12121 ggcttccagc agcagtgttt tcagcaccgc tttgtatggg gaatcgatac tcttgtagag
    12181 ctgccaaagg ctggcaccaa agtactcttc agcagaaagc gagcttaagc caccaagatc
    12241 cagccattca tttggcgtca gcacgccctg cgcgtaaagc gtcatcacat agtcgtcgta
    12301 atgctcttct tcgtcgcacg gcaccatatt ccacagaata cgcttaccgg cgagacgcac
    12361 ggcggtacga taaaattcgt caagcagcag tatatgctgg gtggagccac aatcttcgcc
    12421 ccccaggctg ccgctttcat tatgacggaa gcggttttca tcaatcagga agaagctgac
    12481 ttccacaccc agcgaggcgg cccagctttc cagcagacta catttacgtt gtagcaactg
    12541 gcgctcttcg ctatcgagcc aggattgatg acagacccag atatccaggt cagaggaaca
    12601 actttgccct acggacgagg tgctgcccat ggtgtataca ccagtaattg gaagctcacc
    12661 tttcggtggg tcctgtactg acattccacg atacagttca agctcgttca ggtagtggcg
    12721 ttgagtttca tcaggcgtgt aaaggcaaat gcctttggga acgttaccat caaggtaacc
    12781 cggcattagc ggatggtgat agtgcaacaa tgtcggcagt agactgtaga cctgttggaa
    12841 tgcaggcccc atagcagcaa gcgcgcgatc cacacgcaat tgatttatgg catccagtct
    12901 ctgtttcaga gtctcaatat agaggtacaa gacgtatcgc ctgatttgct acccgtcatg
    12961 actgtgattc cgccaacatc aacggtaaca cgcggcattc gggatatttc gtatgtcaaa
    13021 ggtaaccgtt accacttttc gcgcctggtt tttttagttt cacgacgaaa aaatggtcta
    13081 aaacgtgatc aatttaacac cttgctgatt gaccgtaaag aaagatgcgc tacatacaag
    13141 tgtagcaccg tttattctct gtaaattcct tattacgaag gctcaaagcg cctgtcagga
    13201 tccactgccc gacctcattt tacggtttgc gcaggcgtct acgtttcacc acaacactga
    13261 catcgctctg gcaaggatgt taggatggac cacggatgat aatgacggta acaagcatgt
    13321 tagacaatgt tttaagaatt gccacacgcc aaagcccact tgcactctgg caggcacact
    13381 atgtcaaaga caagttgatg gcgagccatc cgggcctggt cgttgaactg gtaccgatgg
    13441 tgacgcgcgg cgatgtgatt cttgatacgc cgctggcgaa agtaggcgga aaaggcttat
    13501 ttgttaaaga gctggaagtc gcgctcctcg aaaatcgcgc cgatatcgcc gtacattcga
    13561 tgaaagatgt gccggttgaa ttcccgcaag gtctggggct ggtcactatt tgcgagcgtg
    13621 aagatcctcg cgatgcattt gtgtccaata actatgacag tctggatgcg ttaccggcag
    13681 gcagtatcgt cgggacgtcc agtttacgtc gccagtgcca actggctgaa cgccgcccgg
    13741 atctgattat ccgctccctg cgcggcaacg tcggcactcg cctgagcaaa ctggataacg
    13801 gtgaatacga tgccatcatt cttgccgtag ccggactaaa acgtttaggt ctggagtccc
    13861 gcattcgcgc cgcgttgcca cccgagattt ctcttccggc ggtagggcaa ggtgcggtgg
    13921 gcattgaatg ccgccttgat gatgcacgca ctcgcgagct gctcgccgcg ctgaatcacc
    13981 acgaaactgc actgcgtgtt accgccgaac gcgccatgaa tacccgtctc gaaggcggat
    14041 gtcaggtgcc aattggtagc tacgccgagc ttattgatgg cgaaatctgg ctgcgtgcgt
    14101 tggtcggcgc gccggacggt tcgctgatta ttcgcggtga acgccgcggt gcgccgcaag
    14161 atgccgaaca aatggggatt tcgctggcag aagagctact gaataacggc gcgcgcgaga
    14221 tcctcgctga agtctataac ggagacgccc cggcatgagt atcctggtca cccgcccgtc
    14281 tcccgcagga gaagagttag tgagccgtct gcgcacactg gggcaggtgg cctggcattt
    14341 tccgctgatt gagttttctc cgggtcgaca attaccgcaa cttgctgatc aactggcagc
    14401 gctgggagag agcgatctgt tgtttgccct ctcgcaacac gcggttgctt ttgcccaatc
    14461 acagctgcat cagcaagatc gtaaatggcc ccgactacct acttatttcg ccattggacg
    14521 caccaccgcg ctggcactac ataccgtaag cggacagaag attctctacc cacaggatcg
    14581 ggaaatcagc gaagtcttgc tacaattacc tgaattacaa aatattgcgg gcaaatgtgc
    14641 gctgatatta cgtggcaatg gcggtcgtga gctaattggg gattccctga cggcgcgcgg
    14701 tgctgaggtc actttttgtg aatgttatca acgatgcgca atccattacg atggtgcaga
    14761 agaagcgatg cgctggcaat cccgcgaggt gacgacggtc gttgttacca gcggtgaaat
    14821 gttgcagcaa ctctggtcgc tgatcccaca atggtatcgt gagcactggt tactacgctg
    14881 tcgactattg gtcgtcagtg agcgtttggc gaaactcgcc cgggaactgg gctggcaaga
    14941 cattaaggtc gccgataacg ctgacaacga tgcgctttta cgggcattac aataactctc
    15001 ataacaggaa gccataatga cggaacaaga aaaaacctcc gccgtggttg aagagaccag
    15061 ggaggccgtg gacaccacgt cacaacctgt cgcaacagaa aaaaagagta agaacaatac
    15121 cgcattgatt ctcagcgcgg tggctatcgc tattgctctg gcggcgggcg tcggtttgta
    15181 tggctggggt aaacaacagg ccgtcaatca gactgccacc agcgatgccc tggctaacca
    15241 acttacggca ctgcaaaaag cccaggagag ccaaaaagcc gagctggaag gcattatcaa
    15301 gcaacaagct gtacagcttg agcaggcgaa tcgtcagcaa gaaacgctgg caaaacagct
    15361 ggatgaagtc caacaaaagg tcgccaccat ttccggcagc gatgctaaaa cctggctgct
    15421 ggcccaggcc gattttctgg tgaaactcgc cggacggaag ctgtggagcg atcaggacgt
    15481 cacgaccgct gcagcgttgc tgaaaagtgc agacgccagc ctggcggata tgaatgaccc
    15541 gagtctgatt accgttcgcc gggcaattac cgatgatatc gccagccttt ctgcggtatc
    15601 gcaggtggat tatgacggta tcatccttaa gcttaatcag ctttcaaatc aggtagataa
    15661 tctgcgtctg gccgataatg acagcgatgg ttcgccgatg gattccgacg gtgaagagct
    15721 ttccagttcc atcagcgaat ggcgtatcaa tctgcaaaaa agctggcaga attttatgga
    15781 caacttcatt acgattcgcc gtcgtgatga cactgccgta ccgctgttag cgccaaatca
    15841 ggatatctat ctgcgcgaaa atatccgctc tcgcctgctg gtcgcagcac aagctgtacc
    15901 gcgtcaccag gaagagactt atcgccaggc gctggagaac gtctccacct gggtacgtgc
    15961 ttactacgat actgatgatg ccaccaccaa agcgttcctc gacgaggtgg accagttaag
    16021 ccagcaaaat atctcgatgg atcttccgga aaccctgcaa agccaggcga tgctggaaaa
    16081 attgatgcag acccgcgtgc gtaacctgct ggcacaaccg gcagcaggga caacggaagc
    16141 taaacctgca cctgcacctg cacctgcacc tgcaccgcaa gctgatgctc cggcagccgc
    16201 gccgcaagga gaataaccat gctaaaagtg ttattgctct ttgtgttgct gattgcgggg
    16261 atcgtggttg gcccgatgat tgccggccat cagggttacg tgctgatcca gaccgacaac
    16321 tacaatattg aaactagcgt cacgggcctc gcgattattt tgattctggc gatggtagtg
    16381 ctgtttgcca ttgagtggct actgcggcga atcttccgca caggcgcgca cacccgtggg
    16441 tggtttgtcg gacgtaagcg tcgccgtgca cgtaagcaga ccgaacaggc gctgctgaaa
    16501 ctggcggaag gcgattatca gcaagttgaa aagctgatgg cgaaaaatgc cgatcacgct
    16561 gaacaaccgg tggtgaacta tctactggca gccgaagccg cgcaacaacg tggtgatgaa
    16621 gcacgcgcca accaacatct ggaacgcgca gcggagctgg ccggcaatga caccattccg
    16681 gtagaaatca cccgtgtacg tctgcaactg gcccgtaatg aaaaccatgc agcacgtcac
    16741 ggcgttgata agctgctgga agttacgcca cgccatccgg aagtattacg tctggcggaa
    16801 caggcgtata tccgcacagg ggcatggagt tcgctgctgg atatcatccc atcaatggcg
    16861 aaagcccatg ttggtgatga agaacatcgt gcaatgctgg aacaacaggc atggattggc
    16921 ctgatggatc aggcgcgtgc cgataacggt agcgaaggtt tgcgtaactg gtggaaaaac
    16981 caaagccgga aaacgcgtca tcaggtggcc ttgcaggtgg caatggcgga acatcttatt
    17041 gagtgtgacg atcatgatac tgcccagcaa attatcatcg acggcctgaa acgccagtat
    17101 gacgatcgcc tgctgctgcc gatcccgcgt ctgaaaacca ataatccgga acagctggaa
    17161 aaagtgctgc gccaacagat caaaaacgtg ggcgatcgcc cgctgttgtg gagcacactg
    17221 ggtcagtcgc tgatgaaaca cggagaatgg caggaagcat cgctcgcctt ccgcgcagcg
    17281 ctgaaacaac gtccggacgc ctacgattac gcatggcttg ccgacgcgct ggacagactg
    17341 cacaagccgg aagaagccgc agcgatgcgt cgcgacggtt tgatgctaac gttgcaaaac
    17401 aacccaccgc agtaatctat atcgcctcgt tcaggggcga tattttttta caaggatgtc
    17461 aaacatgcgc acaccgtccc gctatatttt ccgcttacca tcacatgaaa ttaatccttt
    17521 tcgggcaacg ctcttgctga ttttgttgat atgtgccgtt ctggctggcg taagttggct
    17581 gattctgtcc ttcgtacgta caggcaatac attcatcttc tggttaacac tttttattgg
    17641 gtatctgata gccattgcga agcaggaaaa aatcaagctc atcgagaagc gccagattat
    17701 ggctgataaa cgtcagggac tttccatttg tcagttcgca cgccaatttt ccccccacac
    17761 cgtagataca tgggtgattc gggctgtgtg gaatacctta caaggaaacg gctatatcga
    17821 ttatccatta ccactgaaag ccagtgataa actggacgat gatctggatt tagtaaacga
    17881 tgcagacgag ttagaagagc tggtcgaaga tattgccgct cgttgtgggc gcgatctacg
    17941 cggaatagaa gataatccgt ttcttcccat caccacggta ggttctcttg taagtgtatt
    18001 aaacgcacaa ccgatgaccc aagagcgacg tagcctgttg tttactcggt cataaaaaaa
    18061 cgcctgctct tattacggag caggcgttaa aacaggtctg tatgacaaca agtgggtgct
    18121 tcactcaacg ttgtgtccat ggtgtctgat gaggcagaag cgacatctgt cagtggacga
    18181 taagcaccgt aaacggctct gcgtcattcc ggagtttatg aggcactaag gcgaacataa
    18241 gagatggaat gagcatctac tcgtttatta tgccacagag aaccgggaaa taacatccct
    18301 taacacttgt tatgagataa ttctgtaatc ctctttgctt cctgagtaat aacttcctga
    18361 gtgaatattt ctcctgcgca caattctaca catatatata atgaataata aaagtcattc
    18421 aattaataac atatatatta attgcagata aaactaaaaa cagcatcaat aatcaacgcg
    18481 atataacatc accgccttac atatcacctg cgccagaggt aggattgaaa acgctctcct
    18541 gattttccaa ttcattttct ggataaataa ataatttatt tttatcacca ttatttatgc
    18601 aatcatcctg tcagggagag ggatctcaat tatcaatgct taattacgtc atcattttga
    18661 cgacatgaaa ccggagcatt ttgcatggaa ttttcgtttt cacccaaact tcttgttgtt
    18721 gctgtcgccg cagctcttcc tctcatagcc agcgcagcag ataccccgtc aaccgccacc
    18781 gcacgcaaag gctttgccgg atacgatcac ccaaaccagt atctggttaa accggcgacc
    18841 actattgccg acaacatgat gccggtgatg cagcatcctg cacaagacaa agaaacccag
    18901 cagaaactgg cggaacttga gaaaaaaacc ggtaagaaac cgaacgtggt tgttttcttg
    18961 ctggatgatg tgggctggat ggacgttggc tttaacggcg gcggcgtggc ggtgggtaac
    19021 cctacaccag atatcgacgc cgttgccagc caggggctga ttttaacttc ggcgtattct
    19081 caaccgagtt cttccccaac ccgcgccacg attctcaccg gacaatactc catccaccac
    19141 ggcattctga tgccgccaat gtacgggcaa ccgggcggtc tgcaagggtt aaccacgctg
    19201 ccacagttgc tgcacgatca gggctacgtc acccaggcta tcgggaaatg gcatatgggg
    19261 gaaaacaaag agtcgcagcc gcagaacgtt ggctttgatg atttccgcgg ctttaactcg
    19321 gtatctgata tgtataccga atggcgtgat gttcatgtca acccggaagt cgccctgagc
    19381 ccggatcgtt ctgaatacat ccaaaaactg ccgtttagca aagatgacgt tcatgccgtg
    19441 cgcggcggtg aacaggaagc cattgccgac attacgccga aatatatgga agatctggat
    19501 caacgctgga tggaatatgg cgttaagttc ctcgacaaga tggcgaagag tgataagcct
    19561 ttcttcctct attacggcac tcgcggctgt cacttcgata actacccgaa cgccaaatat
    19621 gcgggtagct ctccggcgcg cacctcttac ggcgactgca tggtggagat gaacgatatc
    19681 ttcgccaatc tgtataaagc actggagaaa aacggtcagc ttgataacac gctgattgtg
    19741 ttcacctctg ataacggtcc ggaagccgaa gttccgccgc acggtcgcac gccgttccgc
    19801 ggtgcgaaag gttctacatg ggaaggcggc gttcgtgtgc caaccttcgt ttactggaaa
    19861 ggcatgatcc aaccgcgtaa atctgacggc attgtcgatc tggcggatct cttccctacg
    19921 gcgctggatc tggcggggca tcctggggcg aaagtagcga atttagtacc gaaaaccacc
    19981 tttatcgatg gtgtggacca gacatctttc ttcctgggaa caaatggtca gtctaaccgt
    20041 aaggccgagc attacttcct caacggtaaa ctttctgctg tgcgtatgga tgagttcaag
    20101 tatcacgtcc tgattcagca accttacgct tatacccaga gcggatatca gggtggattc
    20161 accggcacag taatgcaaac ggcgggatcg tcggtgttta acctgtacac cgatccgcag
    20221 gaaagcgact ctatcggcgt gcgccatatc ccaatgggtg taccgctaca gaccgaaatg
    20281 catgcgtata tggagatcct gaaaaaatat ccaccacgcg cgcagattaa atctgattaa
    20341 gccggcgcta tcgctgagat ctacctttgc cggatgcgat gctgacgcat ccgacaatca
    20401 accgcaggcg gccacaaaat ggctgctttt ttacttattc accaccagca aatgcgcctg
    20461 cataatgtcg ctggccggac gaccgtgcgc cagcaaatca accattgctt taagatatgg
    20521 cggtagatgg cggaaataac gctgataccc ggcacacaaa taattcagct cgggtttgcc
    20581 gctggcatcg agcataaagc ggtgtttcgg gcagcctccc cagcacgctt ttaacacgtt
    20641 gcaactgcga cactgtgccg gtaactgctt gaatttatct tcaccaaatg cctgctgttg
    20701 cggggaatca atcatttctg caatcatctg ctgaagcata ttccctagtc gatactgcgg
    20761 ataaacatag tgatcgcagg cataaacgtc accgttgtgc tcaacaatca ccgagcgccc
    20821 acaggttggc tgatgatggc aaaccgcgcc cggtgcgccg acaaaattgg cgaacgccca
    20881 ttcgatattc attacgaaaa tcttgccgac gtcgcgctta atccagtggt cgaaaatcgc
    20941 caccagaaac tcaccgaact cttgcgggca caccgaccat tccgtcagtt cgccctgaat
    21001 atcgccggga gcatgtagct taagtccagc atgagcagcc gtttcattag ccaggcgctc
    21061 gaccaccgga ataaactgga tgaactcaac acctgcatca cacagaaaat catagacttg
    21121 caaaggttgt aacgcactgg tgcgattgac gcagaccagc acgttatagt cgacatgatg
    21181 tttttgcagg agcgtcaggg cacgcatcac cagcttatgc gtgggtctgc cacctttggt
    21241 cacgcgatat tgattgtgga tctcagccgg accatccagc gataacccta caagaaaatg
    21301 attttctgcc agaaatccac accattcgtc atcgagcagc acgccgttag tctggaagct
    21361 attacttatc ttcctgccag caccatattt cgcctgtagc gccacggcac ggcggtaaaa
    21421 ctccagcccg agtaacgttg gttcgccgcc ctgccaggta aaagccactt cgttttgggt
    21481 ttcgctggca gcgatatagt gacggacata cgcttccagc gtgtcatcgt ccatatgcgt
    21541 gactggcttt tcgtggtaaa gggattgttt ttcgagataa aaacagtagt cacagttcag
    21601 attacaatca gaaccgctcg gtttcgccat cacatgaaaa gcacgcgttg gaacctgttg
    21661 ctgcatggtc gctccttgcc tgaagtcatc cttcaataag ttaagggcga aatcataccg
    21721 tggcgcaatg cgttattacg ggcgtttatt gcgaagggaa agtgacgaaa tgcacagaaa
    21781 acaaaaaacc ccgccgaagc ggggttcaaa attggtcggc gagagaggat tcgaacctcc
    21841 gacccactgg tcccaaacca gttgcgctac caagctgcgc tactcgccga aatactgctt
    21901 tttgaatttt tagttcaatt ctttaaagtc gtggtgcgag gggggggact tgaaccccca
    21961 cgtccgtaag gacactaaca cctgaagcta gcgcgtctac caattccgcc accttcgcat
    22021 tgtcacaact tctaataatg gggtggctaa tgggattcga acccacgaca actggaatca
    22081 caatccaggg ctctaccaac tgagctatag ccaccactac aaatcttgtt acgcggtatt
    22141 actaccaccg cagctcaagc gccgggacta aatggcgcgc ccgacaggat tcgaacctga
    22201 gacctctgcc tccggagggc agcgctctat ccagctgagc tacgggcgct tagcgccgtt
    22261 gcgggggtgg ataatacgga cttcccaccc ctctgtctag tcccttttta aataaattgc
    22321 gcgtttggtt acggtttgtg cgttttgctg cttattcctc cagtttatgc gctttaccgt
    22381 ggcgattaag cccaaaaact ttataaatcg ccgtcaccgt cagcataaag atgatgccga
    22441 caaacagcga catacgcgta tcttcattaa agtacatgcc gatcaaaacg caaatcagga
    22501 atgccattgt tacgtagttg gcccaaggga acaggattga gcggaacgga tggctggcaa
    22561 ttgccgcttt atgcgcacga cgaaaacgca gctggctaat caatatcaca aaccatggca
    22621 ccatccccgg aagcacgctg gcactgtaga catagacaaa cacacgctgc ggattgggaa
    22681 tgatgtagtt caggcatgag ccaattagca gaatagcaat agataccgcc acacccgcaa
    22741 ccggtacgcc gtgacgggaa actttcgcca tcgccgccgg taactgacgg tttttcgcca
    22801 gtgcatagag catacgtccg caactgtaca tgccactgtt acagccagaa agcgctgccg
    22861 tcagcaccac aaagttaata atgcccgccg cagcggtaat gccgattttg gcgaaagtca
    22921 gtacgaacgg gctgccgttg ctgcctattt cattccacgg gaagatggta acgataacga
    22981 aaatcgcgcc tacgtagaaa atcaggattc gccacagcac cttgcctaca gcgctacgca
    23041 gcgtcacctg cggattcttc gcttcaccgg cagtaatgcc aatcagctcc acgccctggt
    23101 aggacgccac cacaatacac aatgcggtca ggaacccttt ccagccaccc gcaaagaaac
    23161 cgccatgctc tgtgagattg ctaaaaccaa tcgactgccc gccattgcca aagccaaaga
    23221 aaatcacgcc caggccaatg acaatcatca cgataatcgt ggtgactttg atcatcgcga
    23281 accagaactc gatttcgccg tacaacctca ccgcagccag attcgccaac gccaccagcg
    23341 ccaccgcgat caatgcgggt atccactgcg ccatctccgg gaaccagaac tggacataaa
    23401 cgccaatggc ggtgatttct gagatcccca ccgccatcca cataaaccag taagaccagg
    23461 cggtgagata gccaaagaac gggctcatat aacgatgcgc gtaaacggcg aacgaaccgg
    23521 taaccggttc gaggaacaac atttcgccca ttgaacgcat gatgaaaaag acgaacagcc
    23581 cggcgatgat ataggccaac aatacggatg gcccggccca tttcagggta ctggcggccc
    23641 ccataaacag gccgacgcca atggtgcccc ccagggcgat gagttcgata tgtcgagctt
    23701 ccagcccacg ctgtagctct ggtttgttat ctgccataaa tcctcgtgtt gtgtttgcat
    23761 gctttccggt gttaccggtt atcgttatgg gtacatcgag tgttgcgaat gttttcgtaa
    23821 ttcaggagaa atggcaaata aagcattaaa aatttgaatg ctttgtgtaa taaaaaagca
    23881 gacaggcgac ggagtgacca cttcgtcgct ttacaaagag aggaaaatca gaggttgccg
    23941 gtatagtgcc agcgtaaata acgcagcaaa cgaagctgac gcttaatgcg gctcggctgc
    24001 gaaagcaggc ggtagagcca ctccagcccc agcgtttgcc agattttcgg tgcgcgtttt
    24061 acgtgaccgg tgaaaacatc gtaggtcccg ccaacgccca tatacagcgc atctggatgc
    24121 accagacggc agtcgcgcat gaagatctcc tgctttggcg atcccatcgc aacggtgacg
    24181 atttgcgctc cgctggcatg aatgcgttca aacagcgcct gacgctgctc gggtttaaaa
    24241 taaccatcct ggctgccaac gatattcaca ttccactggt tgcgcagttt agcttcagtt
    24301 tgcgccagca cttcaggttt accgcccaca agaaataccg gtgtcccttc tttgcctgcg
    24361 cgcgccatca gctcttccca gagatcggcc ccagcaacgc gggaaacctg cgcctgcggg
    24421 tactttttac gtactgaacg tacaacgctt atgccatccg catatttaaa ttcggcagcg
    24481 ttaattagct cccggacctc ggcgttatct tcaatggtca gcattttttc ggcattaatg
    24541 gcaaccagcg ttccttgctt aagctgcccg tcagcgaaca gataatcgag ggcgtgctgc
    24601 atatcacgcc aaccaatcaa ctgtaagcca cgcagcgtat aggtcggtgc cgtggtgttg
    24661 ttattcatta ttatccttca acctgcgtcc ggagcgatga ttttgttcgt ttatgaatga
    24721 gtccggcgct ttcaaaaagc cagtacaaca gttttgcgat catcagacat gcgccgaaga
    24781 ccacgataaa aaagaccacg cgtgagacaa acgaatccag cccttcacgc gccagcacga
    24841 tcatattgaa gatcgccccg aagcagaaac tgtgcaatat cgcagcctta tagcgattag
    24901 tctcgcggtt gcccagctca tacagccagt cgaaccattt gatgatcagt ccaacaacaa
    24961 tcgccccgag cgggatgaac aacgcgccgc ccatcaccac cagtgagcct ataagcgtag
    25021 gcgagatcgc cagtccggag tggttattca gcacttccca ggtaaagtag ttggcggagt
    25081 tcagcaccat actcgggcga cccggccaca gccaggaagg gataaagaca tagaaatcgc
    25141 ggacaattgg agccaggccc tggaagtcga tgttgtcgta gttctgcaac agcaacgcca
    25201 gattctccca cggtgaaaag gtgtcgcgag tgagatagag aaacgtatag aacgcttcat
    25261 cgccgctcac attcattcca tagcgtttta acgccagcca gaacatgccc acaatcccca
    25321 gcacgcccgc cgccgccagc atccacaacg aaatccagcc gcgaataatg ccaataaaca
    25381 ggaagatagc gaatgcgatg atgatattgg cgcgagtgcc gccgacaatc atataagtca
    25441 gcaagccaaa agcgaccgtg ctgacgagga aaaacagcca cgctttgctg tcctggcgca
    25501 gaaagtagac caccagcatc gccgggatga aaaagtaaaa gaagcgtttt aacgccacgc
    25561 cggagacttc actggagaag atctgactgt aggagttaag ccggaacagc aaaaagccgt
    25621 tgtgcatgaa gaagatgccg acgcttacca gcgcgatgcc catcaggatc acccacgtga
    25681 gattggtttc cacgcggttc atggtaaaca gcggacggcg cggtacatca gcaacgcgtt
    25741 tgcgtaggcg ggttttgtag gtgacgtagt aaaccgcgta gaagcagccc gcagaaagca
    25801 acgcctgcaa caagatttct ggcggcgcgg caccaacatc aaagcgaaaa accagcacgc
    25861 tggtcagcgg gaagccgaag aaaaaggtga gcaaaaacag caatgaaaag aagacattga
    25921 agttaaagcg cacacggcga aactcaaacc aggtcagcgt ggcaataaac agcgtgcaga
    25981 gcagccagac aacaaacagg ccactgaatt gcagcagact catgcgacct ccccggcggc
    26041 aatcgccaac gcccgctgcc agccttgcag atagttcggg ctaaagaagg caatggtgtt
    26101 tttatccacc gacaccaact ggcgctgcgc ttcacgcaca atatcctcgt tgagatcgtc
    26161 ggtagtaaac agcaccggca aatgctgttc cgtcatatcc tgccagaacg gattttcccg
    26221 gttaagcaca caaggaatgc ccgcctgaat cagtaagcac agcgtaccaa tgccctgctg
    26281 gcgggcaaaa ataaagtaac caagatcgca ctgacgaagt agcgccagat aggcgtcaaa
    26341 ttccagtttt tcgctcagag tttgtagatt ttcttcgctg aataactcca gccccgcctg
    26401 acgaacttcc tcgatgtacg cttcgttatt aggcggatat cccatcggca ccaccacttt
    26461 taccgtatcg ccaaattgct gataaacggc gcgcaaggca gcaatatgtt cattgctgcg
    26521 gtcaccggag ttccccacca gaatggtcat tttcccttca cgttgccgat cattcgccat
    26581 catattgagt gaagggtcca tccgcgtcgg gaagtacagc agttctcccc gcacctttgg
    26641 atgcgttttg gcaaaaaagc tcaaatcacc gcgggtggca aatacacagc cgactctctt
    26701 ttgcgccagg cgacgtagcg ggtaaaaaag cttatatctc aagccactgg aaagctcgta
    26761 caggtctgcc ccccagatat gccagtaaaa ctggctgggc ttaatgccac cactcagcag
    26821 agccagccac agtgtgggat tgaactgacc gtggaagaaa aaacgctgct gacggttagc
    26881 ttttgctttc gcgatgaccg cttccgccag cgattttttc ccagggaaaa attgcacaga
    26941 aagcgccgga cagctatcac ttaagccgtc gtccttgcca acaaccataa actcgcgcgc
    27001 gtgctcgctc gtcgcggcca gcgcgtcatt gaaaaaccgc aaaacggttc ggttatggtg
    27061 agggatatcc gatcccagta cgtgaatcag tacagtcatg cccgcctacg ccagagtaaa
    27121 aacacgccac aacaaagaga aaaatagacg atataggttg ccatataggc ctgcgccgcg
    27181 cccagtgcac catgcgcagg gattagccag tgggcaaata ccatcaataa agtgaactgg
    27241 ctgacttccg ccagaatata aaaccgcagt gacgctttgg cgatcaccag ataaccaaag
    27301 acataagcgc ccacttttaa cacatcaccc accaactgcc aggcaaagag atcgcgcata
    27361 gcggtaaatt tattcgacaa cagcagccag atagcaaaat cacgcagcaa ccagacggta
    27421 aaactcgccg ccgccactgc cggcaagacg aatttaagcg atttaaccac ttcccgggtg
    27481 atatcgcgct tttccgttag ccgcgacaac gtgggcagca aatatacgct gaacgatgcc
    27541 gtaataaatt gcaggtaggc atcggaaata ctgctcaccc cttgccagat ccccacctca
    27601 tcccagctat actgcgccgc cagcagttta cgcatcatga tgtaagcaac aggcaaggtc
    27661 accgacgtaa tcaacgccat gagcgtaaat ttgctcaact gccctgccag accgttatcc
    27721 cagctgggtt tcagatagct taacgggatg acaccacgtt tgatcaacat gatggcggca
    27781 ggaattacca ccagcgcggg aatcagcgcc agacccagca acgccccttc ataaccgccc
    27841 aaacggtaac tgacgtagta cgcgagaacg ccaatcaagc tgccaacaat cagagataac
    27901 gcattacctg cggcatcgcg aaagcctttc atcagcgcca gtaacaggtt gccccaggcg
    27961 atccccattt gcaccagcgc cactaaacgc accagcccct gatagtcggt attaccaaac
    28021 aatccctggc tgattggcgc agctgccagc acaaaaacca gcgccatcag cgtagagaaa
    28081 ccaagtacca tcgctgatga agtgccgacc acgcggcgca gctgttgcgg attatcatgg
    28141 tactgggcaa cgtatttggt tacaccgtta aagatgccag ccccggcaag cacgccgagc
    28201 acggtaatca actggcggaa atttgccgcc agcccaagcc ccgccggacc aaatgacacc
    28261 gccagcaact taccgactag taacccggca ccaatcttga ccagtgtact ggccgccgtc
    28321 cacaaggacg cttttgccaa cgacatatca ggagaagtag ttcaacaaag tcgcaattac
    28381 cgtacgctga ttgacgggcg acaggttgta gaacagcggc aggcgcagca ggcgctcgct
    28441 ctctttggtg gtgtagcgat cttcaccgtg gaactcacca aagtgttccc ccgcagggca
    28501 accgtgcagc ggaatgtaat gaaacaccgc catgatttcc gcttctttca gaaagttaat
    28561 caacgcgctc cggtcatcaa tatcccgcag tttaatgtag aacatatgcg cgttctgcac
    28621 gcagccatcg ggaatcgacg gcagctcgat acgcccattt tttgccagag gcgccagtgc
    28681 atcgtagtag ttttgccaca gcgccagacg ctgctgattg atacgatccg ctgcttccag
    28741 ttgcgcccac aggtacgctg cttgcagatc ggacatcaaa tagctggagc caatatcgcg
    28801 ccaggtatat ttatcgacct gaccacggaa gaactggctg cggtttgtgc ctttttcacg
    28861 gatgatctcg gctcgttcga tcaacgcttt atcgttaatc agcgtcgcgc cgccttcacc
    28921 acccgccgtg tagtttttgg tttcatggaa gctaaagcag ccaatatgac caatggttcc
    28981 cagcgcacgc cctttgtaag tggacatcac gccctgagcg gcatcttcca ccacaaatag
    29041 attatgcttc ttcgccaacg ccataatagt gtccatttcg caggccacac ccgcgtaatg
    29101 gaccggcacg ataacgcgcg ttttgtcggt gatcgccgct tcaatcagcg tttcgttgat
    29161 gttcatggtg tccgggcgaa catccacaaa gacgattttc gcgccacgca gcacaaaggc
    29221 attggcggtg gagacaaagg tgtagctcgg catgatcact tcatcgccag gctggatatc
    29281 gagcagcagc gccgccatct ccagcgaagc ggtgcaggac ggcgtcagta acactttggc
    29341 gctgccaaaa cgttgctcca gccactgctg gcagcgacgg gtaaaaccac catcgccgca
    29401 cagtttgccg ctacccattg ccgactgcat atagtcgagt tcggttccca ccaccggcgg
    29461 tgcgttaaat ggaatcatgt gatcacctgt ataaccagta cgcggtgctt tctacattcg
    29521 caccactttg tatgtatcgt ttaagcgcgg cggtgttgcc catctgggtc gccacccgca
    29581 aagttgtttt accgcgagca tacgcccagt ttagcgccgt ttgcattagc tcagcacctg
    29641 caccgcgtcc agccagcagg ccaattcgcg catctgtcgc attgagttcc cgtaaagaga
    29701 cataaccgcg aatatcgccg gacgccgcac gtaaaatcag acattgatga tcaaaggtgc
    29761 cgcgcacggc attttcaatc cactgtgcat aaaagcgacc gctggcgtca ggcgcatacc
    29821 acggcgcacg aaaacggctt tgcgcaaatg cggcgctggc taactgacgt aatgcgggaa
    29881 tatcggtctc ttgtgccact actgcaccgc tatcactgac attgttcacg ggtagtgcca
    29941 aatcaacttc accttctatc agggagaatc ccagctgttg cagagcatcc agttcacccg
    30001 tatttgatgc cgcaattttg gcctgcaccc gtgaccacgg cgctaaggcg tctggcgtca
    30061 ggagtgccgc gtcagggcta atacgcacaa tggcgctgtt aacaccaaag aaggcgtttt
    30121 cccaggttag tggctcaata ctggcgcgga cgggcacgaa gtaactccag cagatattgg
    30181 ccgtagccag ttttcgctaa tgaactggca gcacgcttca caccctcgtc atcgagccag
    30241 ccgttacgcc aggcaatctc ttccaggcag gcaatcttaa agccctggcg tttttctact
    30301 gtctgcacaa aagtgctggc ctcaatcagg ctgtcgtgag tgccggtatc cagccaggca
    30361 aatccgcgcc cgagcagttc aacggtcagg ttgcccgcct cgaggtacat ctggttgatg
    30421 gaggtaatct ccagttcacc acgctccgac ggcttcacct gctttgcgta ctccacgact
    30481 ttactgtcgt agaaataaag cccggtcacc gcccagtttg atttcggctg ttttggtttt
    30541 tcttccagcg agatagcgcg gaaattgtcg tcaaactcca ccacgccaaa gcgttccggg
    30601 tccatcacct gatagccaaa taccgtcgcc ccttccgtgc gcgccgcaac atgacgcagt
    30661 ttcggactga agccctgtcc gaagaagatg ttatcgccca gcaccagaca agaaggttca
    30721 ccgttgagga aggtttcacc gatgataaag gcctgcgcca ggccgtccgg actgggctgt
    30781 tcggcatatt ccagctggat accgaactca ctgccgtcac ccagcaggcg ctggaaataa
    30841 cctttatctt ccggcgtagt gatgatgaga atttcgcgga taccggccag catcagcacc
    30901 gacagcggat agtaaatcat tggcttatcg taaatcggca acagttgctt agatacgccg
    30961 cgcgtaatcg gatgcaatcg ggtgccggaa ccgcccgcca ggataatacc tttcatgttt
    31021 gcctccgctg aaaattagcc tttcagacct aaacgctcgc cctgatagct gccgtcctgc
    31081 acctgcttcc accagctttc attagccaga taccactgca ccgttttacg cattccactt
    31141 tcaaaggttt cctgcggcag ccagccaagt tcacgggcaa ttttcgaagc atcaatggca
    31201 taacgcagat catgccccgg acggtcagcg acaaaggtga tcaggtcacg atagtgcgcc
    31261 acgccgtgcg gcttattcgg agccagttct tccagcagct cgcaaatggt ttccacaaca
    31321 tcgagattct tacgctcgtt gtgaccacca atattatagg tttcaccgac tttcccggtg
    31381 gtcgccacgc aatacagcgc gcgggcgtga tcttcaacat acagccagtc acggatttgc
    31441 tgcccgttgc catataccgg cagcggttta cccgccagcg cgttgaggat catcagcggg
    31501 atcagttttt ccggaaagtg gtaaggaccg tagttattcg agcagttggt gataagcgtc
    31561 ggcagaccat aggtccgcag ccaggcgcgc accagatggt cgctgctggc ttttgacgcg
    31621 gaataagggc tgctcggcgc atacggcgtg gtttcggtga agaaatcatc cgtcgagtgc
    31681 aggtcaccat atacttcgtc ggtggagata tgatgaaaac ggaacgctga ttttttatct
    31741 tccgtcagcg cagtccagta agcccgcgcc gcttcaagca gtgtataagt cccgacaatg
    31801 ttggtttcaa taaacgctgc cgggccgtca atagaacggt caacatggct ttcggctgcc
    31861 agatgcatga cacagtctgg ctgatactca gtgaatacgc gcgccagttc tgcccgatcg
    31921 cagatatcaa ctttctcaaa ggcaaagcgc tcgctttgcg cgaccggtgc cagcgacatc
    31981 aggtttccgg cgtaggtcag cgtatcgacc accaccaccg cgtcgctcgt ttcgttgatg
    32041 atataacgca ccagcgccga gccaataaac ccggcaccac ctgttatcag aatctttctc
    32101 atcagcgcca gactcctttg gcatcgacga catactgctg atggacgttg tcgccattga
    32161 taactttgaa ctgactatga tcgaccagca tcaccagcac atctgccgtt gccagcgcct
    32221 cgtcaagctg cgccagagta caaagcccgg tcagtttctt cggcaactgg tggatgttag
    32281 gctcaacaac cagcgtttcg ccgctgtgcc actgggcgat cagttcagcg atttccattg
    32341 ccggactttc gcgcaggtca tcaatattcg gtttaaacgc cagaccaaag caggcgattt
    32401 tcagttcatt ggcgcgttta tcggtagcag ccagacaatc agccaccgcc gctttcacct
    32461 gatcgataac ccagaacggt ttgtgatcgt tcacttcgcg cgcggtacgg ataagccgcg
    32521 cctgctgggg gttctgtgcc acgataaacc acggatcaac agcgatgcag tgaccgccca
    32581 cgccagggcc tggctgaaga atattgacgc gagggtgacg attcgccagg cgaatcagtt
    32641 cccagacgtt aatcccctga tcggcacaaa tcagcgacaa ttcattagca aaagcgatat
    32701 tcacatcgcg gaagctgttt tcggtgagct tacacatttc cgccgtccgc gagttagtga
    32761 cgacacactc accttcgagg aaaattttgt acagttcgct ggcgcgggcc gaacaaaccg
    32821 gcgtcatacc accaatcacg cgatcgtttt taatcagctc gaccataacc tggcccggta
    32881 atacgcgttc cgggcagtaa gcaatgttga cgtccgccaa ctcgcccacc tgctgtggga
    32941 aagtgagatc tggacgcatc tctgctaacc attctgccat cttctcggtt gaccccaccg
    33001 gcgaggtgga ttcaaggatc actaacgcgc cttttttcag cactggcgca atggagcgag
    33061 cagccgattc aacgtaggtc atatctggct catgatcgcc tttaaacggt gtgggtacag
    33121 caatcaacca ggcatccgct tcaactggcg tcgtgctcgc tcgtaaaaaa ccgccttcta
    33181 cggcagtttt tactacgctc gccaaatcag gctcgacgat atggatttcg ccacgattga
    33241 tggtatcaac cgcgtgttgg ttgatatcga caccaatcac ctgtttttgc cttgaggcaa
    33301 acgcagctgc tgtaggcagc ccgatgtaac ccagtccgat aacagaaatg gtcgcaaaac
    33361 tcatagtgat atccgattat tttttaacgc ttccagaatg cgagagcatg cctgaccatc
    33421 accatacggg ttatgggcgc ggctcatagc ttgatattcg ttttcgtctt ttaaaagacg
    33481 cgtcacttcc tcgacaattc gctgcttatc cgtgccgacc agacgcaccg tacccgccgt
    33541 caccgcttcc ggacgctcag tggtatcgcg catcaccagc accggtttcc ccagcgaagg
    33601 cgcttcttcc tgaatgccgc ctgagtcggt caaaatcagc caggcgtggt tcatcagcca
    33661 gacaaacggt aaatactcct ggggatcgat cagaatgaca tttttcacat gccccagaat
    33721 gcgattgacc ggctctctga cgttcgggtt gagatgcacc ggatagacaa tctggatgtc
    33781 ctggtgcgtg gtggcgatgt ctgccagcgc atggcagatt tcttcaaagc cacgaccgaa
    33841 gctctcacgc ctgtgaccgg tcaccagaat catcttttta tcggggtcga taaacgggta
    33901 atttgccgcc agttctgaac gcagcgtatc gctgctcatc acctggtcac gcacccataa
    33961 cagtgcatca atgactgtat taccagtaat gaagattcgg ctatccgcaa cgttttcacg
    34021 cagcaagttt tgccgggaag tttcggttgg agaaaaatga tacatcgcca gatgcccggt
    34081 caatgtacgg ttagcctctt ccggccacgg cgaatagaga tcgcccgtgc gcagaccagc
    34141 ctcaacgtga ccaacaggaa tacgctgata aaacgccgcc aggctggttg ccagcgtcgt
    34201 cgtagtatcg ccgtgaacca gcacgacatc tggtttgaac tcggcaagaa taggttttag
    34261 cccttccaga atccgacagg ttatctctgt aaggccttgt cctggctgca ttatgttgag
    34321 atcgtagtca ggtacaatgg aaaagagttt cagcacctga tcgagcatct cccgatgctg
    34381 cgcagtgacg caaactttag cctcaaaaaa aggatctttt gccaacgcat gcaccaacgg
    34441 tgccatcttg atggcttccg ggcgcgtacc aaatacagtc agtactttca catcgattct
    34501 cttcgaataa gcggcgagcg cctttgcgct caccgcagca gtgttgctat ttcgagcaac
    34561 ggcgggttaa tgcgacacca gccccgatca gtcccccgac aatgccccac ataatcatca
    34621 ggaaggcacg acgtgggcta tcgcgtttta ccggttcttc cggcgtacgc aaatagcgat
    34681 aggtctgaaa acgcggatcc agggttggac caacattcag ggtgtttaac atggcccgat
    34741 tttgatcata gtcgagatca aaggccggac cgacggcctg taaattttcc agtcgagcct
    34801 ggagcattgg acgcccaagc aggaacattt ctgaatcagg taattcctcg gcaggcacat
    34861 ctgtcgcact gcgcgaaata ttatgctgct cagcaatttt cagcgcctgt tcaatactgt
    34921 tcatccggcg gtcatagatg gctttcgcca cctcttcctg acgcttcacc tgagctttca
    34981 tctggatagt gcgtgccgcc catgcgcctt tcagctcatc attcagatgg ctggctgcac
    35041 gctggctggc aaaagcaaca tactgacgta acaggttatt agcgtcaggc gcggtttcgg
    35101 caataagctt cacgctgtca ttgaccgcgc gggtaaagtc accgggaata aacacgatgt
    35161 tgttaatcat ttcatccagc aacgccgcat cggctttgct gttgcccacc atccgctgtt
    35221 tgtaatagtc ggtttgcagc cagaactctc tgcgggtatc ccacgaggcc agttgcataa
    35281 caaactcttt ataagcttcg tccatgaccg atggttggtc ggcagaagcc atgtttgaac
    35341 ggacatccag gttacgcaaa aattgctgct gtgagtagta cccgcccagc atattcaccg
    35401 ttggacgatc ggtaatcgcc gtcgcgctcc actcctgacg agcaaaaaaa gtatacgcca
    35461 gcgcgattaa cgcaaacgcc agccccatgc caataatcca tagcttccca gcccacaagg
    35521 tacgaaacaa cccacgaata tccagttcat tttcagcgtc ttcggccggt ttcccaggca
    35581 ttggttgtgt catcacatcc tcatttattt ggttaaattg gggctgccac cacgatttct
    35641 acgcagtctg cgttttacgc gcttaataaa gcgagcaact ttccaggcac gcttgatgca
    35701 atatccatag aggaagaatg ctagcaaaaa gagcaccagc atgacccact ccgggacaaa
    35761 atgagaatat tctgccagca cgccaatgga agcgagcaat gctgcggcaa gggtaatcag
    35821 cacaaacgcc tggcgggaag taaacccggc acgcatgatc aaatggtgaa tatgctgacg
    35881 gtctggagag aatgggctca tgcctttacg caggcgacgg tacataatcg ccaccatatc
    35941 cattagcgga atggcgataa tccacaaagc ggtaaccggg ctgatgggat gagttttgcc
    36001 ctgggtcgtt tcgagcagga tccagataac ggtaaaacca atcagcgtac tgcccgcatc
    36061 ccccataaag actttgtagc ggcgacccag gataccaagg ttaagcatga tgtatggcag
    36121 gatggcggcg atcatcgcaa agcaccagat tgcgagactg gtttgcccgt cgaaccacaa
    36181 aatcataccg attgctgcaa acgagacgca ggacaacccg cccagcaagc catcaatgcc
    36241 atcaaccatg ttgaacgcat taatggccgc ccagacggca aatagcgtca ggaagtaacc
    36301 aaacggtccg agcaccatct cccaggagcc aaagatataa cccaggctac tgagataaag
    36361 tttgccgaac accatcataa caatgccaac agcggcctgt atggtggctc ggatttttac
    36421 gctgatatca aaacggtcat ccagcgcgcc aatgaaaaca agcacaccag cacaagcgag
    36481 atagagagat gcatgcggaa tatagtagtc gacaattccg aacgtgaagc aaatccctgc
    36541 gtaaaccgaa atccccccaa cgagaggtat caatccctgg tgacgtttgc ggaagtttgg
    36601 tttatccact aaaccgactt tttttgccac cttacgggca aaaaacagaa acagtgtcgt
    36661 gaataaaaaa atactgatga gatcagtact cactgtcagt aaattcacaa tgcatgctct
    36721 cagagaaaat tattagcaga agtataacca cgaagacctt tattcagaaa ggaaagtccg
    36781 ttccgaacct accagcacta tgcgaaaatt aaccacttga tatgcaaatt gcataacaca
    36841 ccagcaaatt ccaggaattt tcctaacatc gccagcgcgg cattaagatt acagatataa
    36901 aagcaaaacg ccacgtaaac acgtggcgtt tttggcataa gacaaattta tgagcgtttc
    36961 atcatttcga agaaatcgtc attggtcttg gtcattgcca gtttattaat gaggaattcc
    37021 attgcatcga tttcgcccat cgggtgaatg attttgcgca ggatccacat tttctgcagt
    37081 tcttcctgag tcgtgagcag ctcttcttta cgggtaccgg aacggttgta gtcgatagcc
    37141 gggaagacgc gtttttcagc gatcttacga gagaggtgca gttccatgtt gcctgtacct
    37201 ttaaactctt cgtagataac ttcgtccatt ttagaaccgg tatcgataag cgccgtcgcg
    37261 ataatggtca ggctgccgcc ctcttccacg ttacgcgccg caccgaagaa gcgtttcgga
    37321 cgatgcaggg cgttggcgtc cacaccaccg gtcaacactt tacctgacgc cggaacaacg
    37381 gtgttgtaag cgcgcgccag acgagtgatg gagtcgagca gaatgataac gtctttcttg
    37441 tgctcaacca ggcgtttcgc cttctcgatc accatttccg caacctgaac gtggcgagat
    37501 gcgggttcgt caaaggtaga agcaacaact tcacctttta ccagtcgctg catctcggtt
    37561 acttcttccg gacgttcgtc gatcagcaga accatcagca cacaatccgg gtggttgtaa
    37621 gcaatgctct gagcaatgtt ctgcagcagc atggttttac cggctttcgg cggtgccaca
    37681 atcagaccac gctgaccacg accgataggt gatgccagat ccagtacgcg agcggttaaa
    37741 tcttccgtag aaccgttacc acgttccata cgcagacgag agtttgcgtg cagcggggtt
    37801 aagttctcaa agaggatttt gttgcgggcg ttttcaggtt tgtcgaagtt aacttcgtta
    37861 actttcagca gcgcaaaata gcgttcacct tctttcggcg ggcgaatctt accagagatg
    37921 gtatcaccag tgcggaggtt gaaacggcgg atttggctag gggaaacgta gatgtcatca
    37981 ggaccggcga ggtaggagct gtctgcggaa cggaggaaac caaatccatc ctgcaatatc
    38041 tccagtacgc catcaccaaa gatatcttcg ccactctttg cgtgctgctt caggatggca
    38101 aaaataatgt cctgcttacg catacgagcc aggttttcca gccccatatt ttcgccgaga
    38161 gtgatcagct cagaaaccgg cgtattcttt aattcggtaa gattcatagt ggtgtgagtt
    38221 cttaaacttg gggtaaatct cgaacttaat gttgtgaatg gtatggcagg atcatccatg
    38281 cctgtttacg gtcatcgact catgtctttt cgctgcctgg tcacaggaga gtacgcagaa
    38341 ctgaaacgac aagacggatt gagtgacgag ccagaaatct gttcacttcg catttaagat
    38401 aaaacgggaa gcgttggaaa ttacaagatt caaacttaat aaggtatgtt taatacgaag
    38461 tcaacactaa gttagcatga ctcacgccgg gcgtccagtt tttagcgacg gggcacccga
    38521 acatgaaatt cccttacgcc aggttagcgt cgaggaactc tttcaactga cctttagaca
    38581 gtgcgcccac tttggttgcc gccacttcac cgtttttgaa cagcagcaga gtcgggatac
    38641 cacggatgcc atatttcggc gcagtgccag ggttttgatc gatgttcagt tttgcaacgg
    38701 tcagtttgcc ctgatattcg tcagcgattt catccagaat cggggcgatc attttgcacg
    38761 gaccgcacca ctctgcccag aaatcgacga ggatcgcccc gtccgctttg agtacatccg
    38821 tgtcaaaact gtcgtcagtc aggtgaataa ttttatcgct catatataac tccacaggaa
    38881 taagcctggc gtgttggttt cgttgttggt gtaacattaa ccaactaaag gttgacttta
    38941 tttcaccgga tacgctttcg taaagcaata gtaagctgat attctaccac actatgagca
    39001 aaacacattt aacagaacag aagttttccg acttcgccct gcatccgaag gttgtagaag
    39061 cccttgaaaa aaaagggttt cataactgta cgcccattca ggcactggcc cttccgctga
    39121 cgctggcggg tcgtgacgta gccgggcagg cgcaaaccgg taccgggaaa acgatggcgt
    39181 ttcttacgtc aacgtttcat tatcttctct ctcatcccgc gattgctgat cgcaaggtga
    39241 atcagccgcg tgccttaatt atggcaccga cgcgtgaact tgccgtgcag atccacgccg
    39301 acgcggaacc gctggcggaa gctaccggcc tgaagctggg tctggcttac ggtggtgatg
    39361 gctacgacaa acagctgaaa gtgctggaaa gcggcgttga cattctgatt ggcaccacgg
    39421 gtcgtttaat tgactacgcc aagcagaacc acattaacct cggtgccatt caggtggtgg
    39481 tgctggacga agccgatcgc atgtacgatc tgggctttat taaagatatc cgctggctgt
    39541 tccgccgtat gccgcctgca aaccagcgcc tcaacatgct gttctccgcc acgctttcgt
    39601 accgggtacg tgaactggcg ttcgagcaga tgaacaatgc cgaatatatt gaagtggaac
    39661 cggaacagaa aacgggccac cgtattaaag aagagctttt ctacccttct aacgaagaaa
    39721 aaatgcgttt gctgcaaacg ctgatcgaag aagagtggcc agacagagcg attattttcg
    39781 ccaacaccaa acaccgttgt gaagagatct ggggccacct ggcggcagat ggtcatcgtg
    39841 tcggtttatt gacaggcgat gtcgcgcaga aaaaacgtct gcgtattctt gatgaattta
    39901 cccgtggcga tctggatatt ctggttgcca ccgacgttgc cgcgcgtggt ttgcatattc
    39961 ctgctgtgac acacgtcttt aactacgatt tacccgatga ctgtgaagat tacgttcacc
    40021 gtattggtcg tacaggtcgc gctggcgcaa gcggtcattc catcagcctg gcgtgtgaag
    40081 agtatgcatt gaatttgcct gctattgaga cctatattgg tcactcaatt ccggtaagta
    40141 aatacaatcc ggacgcattg atgaccgatc tgccaaaacc gctgcgcctc acgcgcccgc
    40201 gcacaggcaa tggtccgcgt cgtactggcg ctccgcgtaa tcgtcgtcgt tcaggttaaa
    40261 gaaaaaatgt catactccaa atcattcaag ctgtatcaag atggcaagag aatgaatccc
    40321 gatgagttta ctgtcgtaag tgattcaggt gaaagaatgc agccaacaca gagacagatt
    40381 gaaggatgaa gagtatgggt tccacctcgt cgctgtatgc agccattgat ctcggttcga
    40441 atagttttca tatgctggtt gtgcgcgagg tggctggaag catccagacg ctgacgcgaa
    40501 taaaacgcaa agtgcgtctg gctgctggcc tgaatagcga aaatgccctg tctaatgaag
    40561 caatggagcg cggttggcaa tgtctgcgcc tgtttgctga acgtctgcaa gatatccctc
    40621 ccccgcaaat tcgcgttgtc gctacggcga cattacgcct tgccgtcaat gcgggtgatt
    40681 ttattgccaa agcgcaggaa atcctcggtt gtccggtaca ggtgatcagc ggtgaagagg
    40741 aagcgcgtct gatttatcag ggcgttgctc acaccactgg cggtgccgat cagcgcctgg
    40801 tggtggatat cggcggagcc agtactgaac tggtaaccgg cacgggtgca caaaccacct
    40861 ctttgttcag cctgtcgatg ggctgcgtta cctggctgga acgctatttt gccgatcgta
    40921 atctggggca ggaaaatttt gatgctgcag aaaaagcggc acgcgaagtg ttacgtccgg
    40981 ttgccgatga attacggtat cacggctgga aagtgtgcgt tggcgcttcc ggcaccgtgc
    41041 aggcgttaca ggaaatcatg atggcacagg ggatggatga acgcattacc ctggaaaagt
    41101 tgcagcaact gaaacaacgc gccattcatt gcggtcggct ggaagagcta gagattgacg
    41161 ggctgacgct ggaacgtgcg ttagtgttcc cgagtggtct ggcgatcctg atagccattt
    41221 ttaccgaact gaatattcag tgtatgaccc tggcgggcgg tgcgctgcgt gaaggcctgg
    41281 tctacggtat gttgcatctt accgtcgagc aggatattcg cagccgtacg ctgcgtaata
    41341 ttcagcgccg ctttatgatc gatattgatc aggcacagcg cgtagccaaa gttgcggcta
    41401 acttcttcga acaggtggaa aatgaatggc atcttgaagc aataagccgc gatttgctca
    41461 tcagcgcctg tcagcttcat gaaatcggcc tgagcgttga cttcaaacaa gcgccgcaac
    41521 acgctgctta tctggtgcgt aacctggatc ttcccggttt tacccccgca cagaaaaaac
    41581 tgctggcgac gctactgctc aaccagacta atccggtcga tctctcatcg ctgcatcagc
    41641 aaaatgccgt accaccgcgc gtcgcagaac aactctgccg tttactccgc ctggctatca
    41701 tttttgccaa ccgtcgccgt gacgatctcg tgccagagat gacattacag gctaaccatg
    41761 aactgttgac cttgacgctt ccgcaaggtt ggctaaccca acatccgctg ggtaaagaga
    41821 ttattgatca ggaaagccag tggcagagct atgtccactg gccgctggaa gtgcattaat
    41881 gagtaagtgc cggatgcgat gctgacacat tttttccggc cttgattatt tccctcgttt
    41941 tgccgccatc atcgctttca gattcgccag atggctttgc cctttctgca tccgttcttc
    42001 ggcgctgacc actttgcgct cctgttccca aatcaaatca tcctgcggca gctccagcag
    42061 gaagcggctc ggctccgggc gcaccagttc gccgtactga cggcgttctt tacacagcgt
    42121 aaaggtcaat tccttctggg cgcgggtaat gccgacatag gccagccgcc gctcctcatc
    42181 aatattgtct tcatcgatgc tgctctggtg gggcaaaaac ccttcttcca taccaaccat
    42241 gtagacatag ggaaactcca gccctttcga cgcgtgcaga gtcatcagtt gcacctgatc
    42301 cagttcttcc tcgctctcgc cgcgctccat catgtcgcgc agagtaaagc gcgtcaccac
    42361 ctgggtgagc gtcatcggct catccagttc gctgccttcc agcatctccg tcatccagct
    42421 aaacagttgg ttgacgttct tcatgcgcat ttcggcagct ttcgggctgg gcgatgtttc
    42481 gtacagccag gattcataat ccatgccgtg gatcagatcg cgcaccgcgg caatcggctc
    42541 ccgctccgcc agacgctgga tttctgccag ccagtgagtg aagcgggtca atgcttcata
    42601 accacgtccg ctaagcgtct gactcaggcc catatcaaag ctggcggtaa acatgctttt
    42661 attgcgcgtc atcgcccatt cacctagctt tttcagcgtc gccgggccaa tctctcgctt
    42721 cggcgtgtta acgatacgca gaaatgcgct gtcatcgtcc gggttagtca gcacgcgcag
    42781 ataagccagc aagtccttga tttcaggacg agagaaaaac gacgtaccgc cagatatttt
    42841 gtacgggatg cggttttgca tcaggaattt ttcaaatacc cgcgactgat ggttgccgcg
    42901 ataaagaatg gcgtaatctt tgtactgcgt tttattgacg aagtgatggg cgatcagctc
    42961 gccggtgacg cgctcggctt catgttcctc gttattcgcg cttaaaactt ttagctctgt
    43021 gccgtaaccc agttcggaga acagacgctt ttcaaagacg tgcgggttat tggcgatcag
    43081 gatgttcgcc gctttcaaaa tacgtccgga agagcggtag ttctgctcaa gcttaatcac
    43141 cttcagcgcc ggaaaatcct ggctcagcag caccagattc tgcggacgtg cgccgcgcca
    43201 ggagtagatc gactggtcat cgtcacccac cacggtaaag cgcgcgcggc tgcccaccag
    43261 cagtttcacc agttcatact ggctggtgtt ggtgtcctga tactcatcca ccagcaggta
    43321 gcgaattttg ttctgccagc gctcgcggac ttcttcattg cgttgcagca gcaacgtcgg
    43381 caataaaatc agatcatcga agtcgagaac gttacaggct ttcaggtgtg catcatacag
    43441 cccataacaa tgggcaaaaa tacggtcccg ctcgcccttt gcctctgccg ccgcctgcgc
    43501 cggtgttttg agatcgttct tccagttgga gatggtcgaa attagctgtt gcaggagaac
    43561 tttgtcatct tcaatcagcc cctcggtcaa ctctttaagc aaagcaagct gatcggtatc
    43621 gtcaaacagc gaaaagttag ccttcatccc cagcgccgca tactcgcgtt tgatgatatc
    43681 cagccccagc gtgtggaagg tggaaatcat cagcccacgc gcctctttgc gccccagcgt
    43741 ctgcccgaca cgctctttca tctcgcgtgc cgccttattg gtaaaggtca cagccgcgat
    43801 atgtcgcgcc tgataaccgc aaccgcggat cagatgggcg attttattgg tgataacacg
    43861 agttttaccg gaacccgcgc ccgccagcac caggcagggg ccggtaacga attcgacagc
    43921 ttgttgttgg ccggggttta gacgcatagg aaaatcgctc aatgaaagtc gggaggggaa
    43981 aataacagcg tggtagtata gccagcctca tccttaccac tcaaggcacg atcatggcaa
    44041 aaacagcagc agcactgcat atccttgtaa aagaagagaa actggctctg gatcttctcg
    44101 agcagatcaa gaatggtgcc gatttcggca agctggcgaa gaaacactcc atttgcccgt
    44161 caggcaaacg cggcggtgat ttaggtgaat tccgccaggg tcagatggtt ccggcgttcg
    44221 ataaagtggt gttttcttgc ccggtgctgg aaccaaccgg accgctgcat acccagttcg
    44281 gttaccacat cattaaggtg ctataccgta attaacagca aggccttctc cgggagaagg
    44341 ccttgaactc tgaatcgcta ttaacccgca acagcaatgc gtttcatatc tgtcatatag
    44401 ccgcgcagtt tcttacctac ctgctcaatc gcatggctgc gaatcgcttc atttacatca
    44461 cgcagctgcg cgttatctac cgcaccttcc ggaatagctt tacccaggtc gcccggttgc
    44521 agctctgcca taaacggttt cagcagtggc acacaagcgt aagagaacag atagttaccg
    44581 tactcggcag tatcggagat aaccacgttc atttcgtaca gacgcttacg ggcgatggtg
    44641 ttggcaatca gcggcagttc gtgcagtgat tcatagtaag cagattcttc gatgatgcca
    44701 gaatcaacca tggtttcaaa cgccagttca acgcctgctt ttaccatcgc gatcatcagt
    44761 acgcctttat cgaagtactc ctgttcgccg attttgcctt catactgcgg cgcggtttcg
    44821 aatgcggttt tgccagtctc ttcacgccag gtcagcagtt tcttatcgtc gttggcccag
    44881 tcagccatca tgccggagga gaattcgccg gagatgatgt cgtccatatg tttctggaac
    44941 agcggcgcca tgatctcttt cagttgctca gagagcgcgt aagcacgcag tttcgccggg
    45001 ttagaaagac ggtccatcat cagggtgatg ccgccctgtt tcagcgcttc ggtgatggtt
    45061 tcccaaccga actgaatcag tttttctgcg tatgccggat cggtgccttc ttccaccagc
    45121 ttgtcgaagc acagcagaga gccagcctgc aacataccgc acaggatggt ttgctcgccc
    45181 atcaggtcag atttcacttc cgcaacgaaa gaggattcca gaacgcccgc acggtgaccg
    45241 ccggttgcag ccgcccaggc tttagcgatc gccatgcctt cgcctttcgg atcgttttcc
    45301 gggtgaacgg caatcagcgt cggtacgccg aatccacgtt tgtactcttc acgtacttcg
    45361 gtgccagggc atttcggcgc aaccattacg acggtgatgt ctttacggat ctgctcaccc
    45421 acttctacga tattgaaacc atgagagtag cccagcgccg cgccgtcttt catcagcggc
    45481 tgaacggaac gcactacgtc agagtgctgc ttgtctggcg tcaggttaac caccagatcc
    45541 gcctgcggga tcagttcttc gtaagtgcca actttgaagc cgttttcggt tgctttacgc
    45601 caggatgcgc gcttctcggc aatcgcttct ttacgcagag cgtaggagat atcgagacca
    45661 gaatcacgca tgttcaggcc ctggttcaga ccctgtgcac cacagccgac gatgactact
    45721 tttttaccct gaagatagct cgcgccatcg gcgaattcat cgcgccccat aaagcgacat
    45781 ttgcccagct gtgccagctg ctggcgcaga ttcagtgtat tgaagtagtt agccatggtg
    45841 attcctcgtg atgttgtgct tcttattgtt cggttcgcgt ttgcgagatt gaattcacta
    45901 tatgacagga aatttattgc ggaaattgat atattcacaa cgtcacattg caatttctgc
    45961 aacgtcaaca ttaagggctg cgccattgga tttacgcgat ctgaaaacct tcctgcatct
    46021 ggcggaaagc cgccattttg gccgcagcgc gcgggcaatg cacgttagcc cgtccacgct
    46081 ctctcggcag attcagcgcc tggaagacga tctcggtcag ccgctgtttg tgcgcgataa
    46141 ccgcacggta acgctaaccg aagcaggcga agaactgcgc gttttcgccc agcaaacgct
    46201 gttgcagtat caacagctgc gccacaccat cgatcagcaa ggaccgtcgc tctctggcga
    46261 attacatatc ttctgctcgg tgaccgctgc ctacagccat ctgccgccga ttctcgatcg
    46321 cttccgcgcg gaacacccgt cggtggagat taaactcacg actggtgatg cggcagatgc
    46381 gatggaaaag gtcgtcactg gcgaagcgga tctggcgatt gccgggaaac cggagactct
    46441 gcccggcgca gtggcgtttt cgatgctgga gaatctggca gtagtgctga ttgcccccgc
    46501 gctaccctgc ccggtgcgta accaagtttc ggcagataag ccggactggt ctacagtgcc
    46561 gtttatcatg gccgatcagg gaccagtacg ccggcgcatt gagttgtggt ttcgacgcaa
    46621 caaaatcagc aacccgatga tttacgccac ggtcggcggg catgaagcga tggtgtcgat
    46681 ggtggcgctc ggctgtggcg tagccttgtt gccggaagtg gtgctggaaa acagcccgga
    46741 accggtgcgt aaccgcgtga tgattttaga gcgcagtgat gagaaaacgc cgtttgaact
    46801 gggcgtgtgt gtgcagaaaa agcggctaca tgagccgctg attgaggcat tctggaagat
    46861 tttgccgaac cattaacccg ccaaaaagaa cctgaacgcc gggttattgg tttcgtcgtg
    46921 gcaatcgtaa cccaactcat tcaaccgggt ttcgaaatcc ggttcatggt cgccaagttc
    46981 gaacgccgcc agtacgcgcc cgtagtcggt gccatggctg cgatagtgga acaaagaaat
    47041 gttccagtgc gtacccagcg tgttgaggaa gcgcaacagc gcgcccggcg attccgggaa
    47101 ttcgaagctg tagaggcgtt cctgcaacgg atgcgacgga cgcccgccga ccatatagcg
    47161 cacatgcagc ttcgccattt cgtcgtcgga gagatccact acgctgtagc cgccatcgtt
    47221 gagcatctgc aaaatttctt tgcgctcttc gaggccacgg ctcaggcgca caccgacaaa
    47281 gatgcaggcg tttttggcat cggcaaaacg gtagttgaac tcggtgaccg agcgcccgcc
    47341 aagcagctgg cagaacttca ggaagctgcc cttctcttcc gggatggtta ccgccagcaa
    47401 cgcttcacgc tgttcgccca gttcgcaacg ttccgagacg tagcgcaggc cgtgaaagtt
    47461 cacgttagca ccagaaagaa tatgcgccag ccgctcaccg cgaatgttgt gctgggcgat
    47521 atattttttc attcccgcca gtgccagcgc gccagagggt tccgctaccg cgcgcacatc
    47581 ttcgaacagg tctttcatcg ccgcacatat ggcatcgcta tcgacggtga tgatgtcgtc
    47641 gagatactcc tggcataaac ggaaggtttc gtcgccgatg cgtttcaccg caacaccttc
    47701 ggcaaacagc cccacgcgtg gcagatcaac cggatgacct gcatccagcg ccgctttcag
    47761 gcaggcggag tcttccgctt ccacggcaat cactttgatt tgcggcatca gttgtttgat
    47821 cagtaccgcc acgcccgccg ccagaccgcc gccgccgact ggcacaaata cgcggtcgag
    47881 atgggcgtcc tgctggagca gttccagcgc cagcgtgcct tgcccggcga tcaccatcgg
    47941 atggtcgaac ggcggcaccc aggtgaagcc ctgctgctgt gacagttcga tcgctttcgc
    48001 ttttgcttca tcaaagttcg cgccgtgaag aagcacttcg ccgccgaagc cgcgcaccgc
    48061 gtcgactttg atatcggcgg tggcggttgg catgacgatc agtgccttca cgcctaaccg
    48121 tgcggaagaa aacgcgacgc cctgcgcgtg gttacccgca gaagcggtga tcacgccgtg
    48181 cgctttctgt tcttccgtca ggcccgccat catggcgtat gcgccgcgca gcttaaagct
    48241 atgaactggc tgacggtctt cgcgtttcac cagaatcacg ttatcgagac gcgacgagag
    48301 tttttccatt ttttgtagcg gcgtgacctg cgccgcttcg tagaccggcg cgcgcagcac
    48361 cgctcttaaa tattcggcgc cttccggggc gccggagaga ggttgtgagt ctgccatcat
    48421 taacccccca gtttcgattt atcacgcacc gcgcctttgt cggcgctggt tgccaggctg
    48481 gcgtaggcac gcagcgcaaa ggaaacctga cgttcacgat ttttcggtgt ccaggctttg
    48541 ttgccacgag cttcctgcgc ttcacgacgc gccgccagtt cggcatcgct tacctgtaac
    48601 tgaatgccac ggttcggaat gtcgatagcg atcaagtcac catcttcaat caggccaatg
    48661 ctgccgccac ttgccgcttc cggtgagacg tggccgatgg aaagaccaga ggtgccgcca
    48721 gagaaacgac cgtcggtgat cagcgcacag gctttaccga gacccattga tttcaggaaa
    48781 ctggttgggt agagcatttc ctgcatcccc ggaccgcctt tcgggccttc atagcgaatt
    48841 actaccacat ctccggcgac aactttaccg ccgagaatcg cttctaccgc gtcgtcctgg
    48901 ctttcgtaga ctttcgccgg gccagtgaat ttgaggatgc tgtcatcgac gcctgcggtt
    48961 ttaacgatgc agccgttttc tgcgaaatta ccgtagagta ccgccaggcc gccgtctttg
    49021 ctgtaagcgt gttccagcga gcggatacag ccattggagc gatcgtcgtc cagcgtatcc
    49081 cagcggcaat cctgcgagaa tgcctgtgta gtacgaatgc ccgccgggcc agcgcggaac
    49141 atatttttta ccgcatcatc ctgggtcaca atgatgtcgt attgttccag cgtttgcggc
    49201 aacgtcaggc caagtacatt tttcacatca cggttcagta accccgcacg atccagctcg
    49261 ccgagaatac cgataacacc accagcacgg tgaacatctt ccatatggta tttttgggtg
    49321 ctcggcgcga ctttacacag ctgcggtact ttgcgggaga gcttatcgat atcactcatg
    49381 gtgaagtcga tttccgcttc ctgcgccgcc gccagcaggt gaagaacggt gttggtagag
    49441 ccgcccatcg cgatatccag cgtcatggcg ttttcaaacg ccgccttact ggcgatgtta
    49501 cgcggcagtg cgctttcatc atcctgttcg tagtaacgtt tggtcaattc aacaatgcgt
    49561 ttaccagcat tgaggaacag ttgcttgcga tcagcgtggg ttgccagcag cgagccgttg
    49621 cccggctgcg acaggcccag cgcttcggtc aggcagttca ttgagttagc agtaaacatc
    49681 ccggagcagg aaccgcaggt tgggcaggcg gatcgttcaa cctgatcgct ctgggagtca
    49741 gaaactttcg ggtctgcgcc ctggatcatc gcatcaacca gatcgagctt aatgatctga
    49801 tcggacagtt tggttttccc ggcctccatc gggccgccgg aaacaaagat caccggaata
    49861 ttcaggcgca gggaagccat cagcatcccc ggggtgattt tgtcgcagtt agagatgcag
    49921 accatggcgt cggcgcagtg ggcgttgacc atatattcaa cggaatcagc gatcagttcg
    49981 cgagatggca gtgaataaag catgcccccg tggcccatag cgatcccatc atccaccgca
    50041 atggtgttga actctttggc aacgccgccc gccgcttcaa tttgttcggc gaccagttta
    50101 ccgagatcgc gcagatgaac gtgacccggt acaaattggg tgaacgagtt cacaaccgcg
    50161 ataatcggct taccgaaatc ggcgtcggtc attccggtgg cgcgccacag cgcacgagca
    50221 cccgccatat tacgaccatg agtggtggtg gcggaacggt acttaggcat actttattta
    50281 ctcccagtgt ctgtctcgta aatgggacgg tgcgtgccgt cccatttttt gtatttattg
    50341 attaacttga tctaaccagc cccatttatc ttcggtctcg ccagtgaaga ggccgaagaa
    50401 ggcttgctga atgcgtttgg taaccgggcc gcaacggcct tcaccaacct gaataccatc
    50461 tacactgcgc actggcgtga tttctgccgc cgtaccggac ataaagactt catccgccag
    50521 gtacagggat tcgcgcgaca gcacctgctc acgcacttca attcccagct ctttcgccag
    50581 tttgatgatg gcatcacggg taatacccgg cagcgcggag gaggtgaacg gtggagtaaa
    50641 cagcacaccg tctttcactt caaacaggtt ttcgcctgcg ccttcagaga tataaccatt
    50701 cacatccaac gcgatacctt cctgataacc gtggcggcgc gcttcgctac ccaccaacag
    50761 ggaagagagg tagttaccac cagctttcgc tgcggttggg atggtgtttg gtgcagcacg
    50821 gttccaggag gaaaccatcg catcgatccc ctgctccagc gcttctgcgc ccagatacgc
    50881 cccccacggg aaagcggcga taatcacatc ggttgagtat cccgctggcg ggtttacgcc
    50941 catgccaaca tcaccgacga aaatcagcgg acggatatag gcgctggtga gattgttttt
    51001 gcggatcacg tcgcgacaag cttccatcag ctcatcaatg ctctgcgaaa ccgggaaacg
    51061 atagattttg gcggagtcat gcagacgctg catatgctca cgatggcgga atacaaccgg
    51121 tcctttgtgc gagtcgtagc aacggatgcc ttcaaaaacc gaggtgccat agtgcagcgc
    51181 gtgcgacatc acatgcacct tcgcgtcttc ccagcgaacc atctccccat tgaaccaaat
    51241 gtaatcagct ttcttcgtgg tcatttttat attccttttg cgctcaggcg cggatttgtt
    51301 gtgatgtggt tgtgctctgg cagatagcaa cgtgtgcgac gtccaccagt ttatttaact
    51361 gactaaacag taagtcgacc gaccgtgggc tggcaacggt caattcgata tttatatttt
    51421 gtgcatcgct ggcggcagcc atattcattg agcagacgtg gaaaccacga tgacgcacca
    51481 cgcgtaaaac acgttctaag gtttccggat tgaagcgagc cgatacattg acctgatgtt
    51541 gcatcatgat aatttctcca acatttcaga attactggca ccaggcggca ccagcggcca
    51601 gacgttctca agttcgtcga ttgagacatg aagcaggtat ggcccatcac tgttcagcat
    51661 ggtgtcgagt gccgcttcaa cctggtcttt atgggtgatg tgttggccag ggatgccgaa
    51721 ggcgctggct aacatgagga aatcggggtt atcggtaagg gtggtttcgc tgtatcgttc
    51781 ctggaaaaac agttgctgcc attgtcgaac catccctaac cgttggttat cgagtaagac
    51841 gattttcaac ggtaactgct tgcgttttac ggtgcccagc tcttgcacat tcatcataaa
    51901 agagccgtca ccggagatac agacgacagt atcgttcggt cgcgcgactt gtgcgccaac
    51961 cgccgccggt aaaccgaaac ccatggtgcc taagccgctg gaggtgatga agttttccgg
    52021 gcgagtgtgg acgatgtgct gggcagccca catctggtgc tgccccacat ctgtggtcac
    52081 gatgcaatcc gcaggtttac gatccgacag ttgttttaac aacaacggcg cgtagatagc
    52141 gtcaccagga tggtcgtaac gccaggcatg ttcatcacgc agttgcgcgc agtgttgctg
    52201 ccagtcatcg atatttaacg gctgctgtaa tgctggtaac agagcattta aatcaccctg
    52261 taatgccaca tgtgcctgac gcagcttgtt catttctgcc ggatcgatat ccatatggat
    52321 aacgctggcg tgtggtgcga aggtgttcag tttgccggtc acccggtcat caaaacgtgc
    52381 gcccacggct atcagtagat cgcactcctg cactgcgaag ttcgccgctt tggtgccgtg
    52441 catccccagc atgcccagat agtacggata atctgcttct actgcgccca gccctttcaa
    52501 cgtacaggtg gcaggcattt ttgtggcagc gagaaattca cgcaaagccg aaactgcctg
    52561 cgccatgccc acgccaccgc caacgtacag catcggtttt tgcgcttttg ccagcatctg
    52621 acgcgcttgc tcgacttcgg catgtgggaa agtcacttcg ttttcaacag tggtgaacca
    52681 cggttccaga tcgccgctgg ctaactggat atcttttgga atatcgacca aaaccggacc
    52741 aggacgacca gagctggcga cgtcaaacgc ttcggccatg atacgcggta actcttccag
    52801 tgattgcacc aggaaactgt gcttggtgca ggctaacgac aaccccagaa tatccacctc
    52861 ctgaaatgcg tcagttccga taaacggtgc ggatacctga ccggtgatag caacaacggg
    52921 gatggaatct aacagcgcgt ccgcaagccc ggttatcagg ttggttgcac ctgggccaga
    52981 cgtggcgatg caaacgccag ttttgccggt agcacgggca taaccgatag ccgccattgc
    53041 tgcaccttgc tcgtgtcggc acagcaagtg ttccacgcca ccgtcataca atgcatcgta
    53101 aaccggcata attgcgccac ccggataacc gaaaacggtg tttacaccct gtgcccgcaa
    53161 cgcatgtacc acccactgtg caccattcat agttagttcc ccgtcctgaa tcttgagaaa
    53221 cagaattttg tgctgttatt cattgtctgc tcctcagtta tgtttttaag gtcaaaaaaa
    53281 acccccggac ctttcggtgc gggggtctta gttcgttaag gcttgatctc taagcctttc
    53341 ctcgtccaag tgcagccccg catggtggga taataatcac caccacgcta atcacgacca
    53401 ggctaatcac tcgtagaagg gctgtcattt tgtcttttct tgcatcttgt tcgaaggaat
    53461 gcctaaagag ttaccataga ttttgcgaat agcacaagat attttttggc cgatttttat
    53521 gatgtcttta ataatctcaa gagaaattgt tgttttttaa aaagaaaata gtgagtgaaa
    53581 aaaattcaat ttcagtatga atgttgttcc cttcctcgta gttcatcctt tgcccgctgc
    53641 atttttgcga gcatcattcc accgccagaa caactcaact tcacttgcac aaataaacag
    53701 gaatcagcca ctaaaattca cgaatttgcg ggctacagca gcgatatctt atgcacataa
    53761 tggtgactca aggagggctt atgtcactgt caattgttca tacccgcgca gccctgggag
    53821 taaatgcgcc cccaatcact gttgaggtac atatcagtaa aggtctacca ggcttaacga
    53881 tggtgggctt accagaaaca acggtaaaag aagctcgcga tcgcgtgcgc agcgccatta
    53941 tcaatagcgg atatgaatat ccggcgaaaa aaatcaccat caaccttgct ccagccgatc
    54001 tgccaaaaga agggggacga tatgatttgc ctatcgctat tgcgttgctg gcggcctcag
    54061 aacagcttac agccaataag ttagatgaat atgaattagt cggagaactg gcgcttacag
    54121 gcgctctgcg tggcgttccc ggcgcaatct ccagtgcaac tgaagctatt aagtcgggca
    54181 gaaaaattat cgtcgcgaaa gataacgaag atgaagtggg gctaattaac ggtgaaggat
    54241 gcctgatagc cgatcatctg caggctgtct gcgcgtttct ggaaggtaag cacgctctcg
    54301 aacacccgaa accaactaat gcagtatccc gggcgctaca acatgatctc agtgatgttg
    54361 tcggtcagga gcaaggaaag cgaggactgg aaattaccgc cgctggcggg cacaaccttt
    54421 tactgattgg accgccggga acaggtaaaa caatgctcgc cagccgtatt aatggccttt
    54481 tgccagattt aagcaatgaa gaggcactgg agagcgctgc gatattaagt ctggtaaatg
    54541 ctgaatcagt acaaaaacaa tggcggcaac gcccgttccg ctcacctcat cacagtgcgt
    54601 cgttaactgc gatggtgggc ggtggtgcaa ttccagggcc aggtgaaatt tcgctggcgc
    54661 ataacggcgt gctttttctt gatgagctac ctgaatttga acggcgtaca ctggatgcct
    54721 tgcgagagcc gattgaatcc gggcagatcc atctttcacg cacacgagca aaaataacct
    54781 atccagcccg tttccagctt gtcgcggcga tgaatcccag ccctaccgga cattatcagg
    54841 gaaaccataa ccgctgcaca ccagaacaga cattacgtta tctcaaccgg ctctcggggc
    54901 cctttctcga ccgcttcgat ctctcactgg agatcccatt accgcctccc ggcattttga
    54961 gtaaaacggt agtgccggga gaaaacagca ccaccgttaa acaacgtgta atggccgcca
    55021 gagagcgcca atttaagcgg cagaataaac tgaacgcctg gctggataat ccggaaatac
    55081 gccaattctg caagcttgag agcgaagatg cgcagtggct ggaagaaacg ctgatccatc
    55141 tggggttatc gattcgtgcc tggcagcggt tattgaaagt tgcacgaacc attgctgata
    55201 ttgatcagtc tgacattatc acacgtcagc atttgcagga ggcagttagc tatcgtgcga
    55261 ttgaccgttt gctcatccat ctgcaaaaac tactgacata aaaaaagggc atttcgccct
    55321 ttttattaat cgtcagaatc ggtgtagtct tcagcacctt caacctgcgg tttaccgccg
    55381 gaaagggtgt gaaaacgttt tggacgcttg atacgcgtca tatacttgga ccacacgcgt
    55441 tctgcttctg tcactggttc acgttcgcca cggcatactg ctacgaagag tttctcttcc
    55501 tcggtaaccg gctcgcgttt gccaagatcc aactcattga aggcataacc atgacgctca
    55561 agcagttgtg cctctttgat ggtgaagtca ccatgacgag agaatccacg tggataatgt
    55621 ttattgtcga aatatcgatt agtcgtcgta aagctttccg ccatcctgca cgctcctaat
    55681 tctttgaccg agctagttat ggcgcggagt attagttacg cttgacagag tgtaaaacaa
    55741 aacatttaaa tcataacgac aaataatttt gcggagagca ctgtggatac ggaattgtta
    55801 aaaactttcc tggaagttag ccgaacgcgt cactttggtc gagcggctga atcgctctat
    55861 ctgacccaat cagccgtgag ctttcgaatc agacaactgg aaaatcaact gggtgtgaat
    55921 cttttcaccc gccacagaaa caatatccgt ttaaccgctg ccggagaaaa gcttctgcct
    55981 tatgcagaaa cgctcatgag cacctggcag gccgcccgca aggaggtggc gcatacctca
    56041 cgacataatg agttttctat cggtgccagc gcctcgctgt gggagtgtat gcttaatcag
    56101 tggctgggac gcttgtatca aaatcaggat gtccatacag gcttacagtt cgaagcgcga
    56161 attgcccaac ggcagtctct ggtaaaacag ttgcatgaac gccagcttga tcttcttatt
    56221 acaactgaag cccccaaaat ggacgaattt tgtagtcagt tgctggggta tttcacttta
    56281 gcgctttata ccagtgcccc ttctaaacta aagggagatc ttaactatct gcgactagag
    56341 tgggggccag actttcaaca gcatgaggca ggtttgatcg gtgctgacga agttcccatt
    56401 ctgacaacca gttctgctga actggcacag caacagattg cgatgcttaa tggttgcacc
    56461 tggctacccg tcagttgggc acgtaaaaaa ggcggcctgc ataccgttgt cgatagcaca
    56521 acactttcac ggccgcttta tgccatatgg ctacaaaata gcgataaaaa tgcgttgatt
    56581 cgcgatctat tgaaaattaa cgtgctggat gaagtgtatt aatctgaatg gctggcaagg
    56641 atgccggtag aaggatttac ttcggagagg gttatttcag ataaaaaaaa tccttagctt
    56701 tcgctaagga tgatttctgg caggggcgga gagactcgaa ctcccaacac ccggttttgg
    56761 agaccggtgc tctaccaatt gaactacgcc cctaattagg gtggcggaac ggacgggact
    56821 cgaacccgcg accccctgcg tgacaggcag gtattctaac cgactgaact accgctccac
    56881 cgaattcttt tacaaccacc ggttttatga ccggcttact gct
//
LOCUS       DAPOXO010000023        56748 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPOXO010000023 DAPOXO010000000
VERSION     DAPOXO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 56748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56748
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.023"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            190..732
                     /gene="ecpR"
                     /locus_tag="ROH59_001727"
                     /gene_synonym="matA"
     CDS             190..732
                     /gene="ecpR"
                     /locus_tag="ROH59_001727"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HDX4804218.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKLYKLVQ"
     gene            807..1394
                     /gene="ecpA"
                     /locus_tag="ROH59_001728"
                     /gene_synonym="matB"
     CDS             807..1394
                     /gene="ecpA"
                     /locus_tag="ROH59_001728"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HDX4804219.1"
                     /translation="MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            1451..2119
                     /gene="ecpB"
                     /locus_tag="ROH59_001729"
                     /gene_synonym="yagY"
     CDS             1451..2119
                     /gene="ecpB"
                     /locus_tag="ROH59_001729"
                     /gene_synonym="yagY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HDX4804220.1"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIQNS
                     TDSGRLINIRLERLSSPLDDGQVIAMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            2145..4670
                     /gene="ecpC"
                     /locus_tag="ROH59_001730"
                     /gene_synonym="yagX"
     CDS             2145..4670
                     /gene="ecpC"
                     /locus_tag="ROH59_001730"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HDX4804221.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMTLANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNFGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQIWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTFSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSNIASI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSSANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASGRTDGNAGVIFDTGLENDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     gene            4660..6303
                     /gene="ecpD"
                     /locus_tag="ROH59_001731"
     CDS             4660..6303
                     /gene="ecpD"
                     /locus_tag="ROH59_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HDX4804222.1"
                     /translation="MRVNLLIAMIIFALIWPATALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYLQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            6272..6982
                     /gene="ecpE"
                     /locus_tag="ROH59_001732"
     CDS             6272..6982
                     /gene="ecpE"
                     /locus_tag="ROH59_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HDX4804223.1"
                     /translation="MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNLTKRSPSGGEVSTEPVVVMDTILVVRPRQVQFKWS
                     FDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            7289..7618
                     /locus_tag="ROH59_001733"
     CDS             7289..7618
                     /locus_tag="ROH59_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDX4804224.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYENRSSTCREFAMSGENGEVNEACNRARA
                     KYGLTPL"
     gene            complement(7630..7793)
                     /locus_tag="ROH59_001734"
                     /pseudo
     CDS             complement(7630..7793)
                     /locus_tag="ROH59_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(7867..8481)
                     /locus_tag="ROH59_001735"
     CDS             complement(7867..8481)
                     /locus_tag="ROH59_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HDX4804225.1"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNSAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     gene            complement(8696..8881)
                     /locus_tag="ROH59_001736"
     CDS             complement(8696..8881)
                     /locus_tag="ROH59_001736"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804226.1"
                     /translation="MASGLICHGGFEPHAWGVASLMDVTVLVVASLLVWLLVNRENHY
                     ARGIPQDVQVLHKKAHH"
     gene            8930..9088
                     /locus_tag="ROH59_001737"
                     /pseudo
     CDS             8930..9088
                     /locus_tag="ROH59_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706266.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            9315..9650
                     /locus_tag="ROH59_001738"
     CDS             9315..9650
                     /locus_tag="ROH59_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
                     /protein_id="HDX4804227.1"
                     /translation="MAILITQDRQVANLTPPEGKSRITVSVKSKVGSGLSVESRSGSQ
                     TKSWIYRPYLNGKQIKITLGSYPAMTLSQAREAHADALALVKQGIDPRYARKTEKQQN
                     EQMPIFSQL"
     gene            9858..10634
                     /locus_tag="ROH59_001739"
     CDS             9858..10634
                     /locus_tag="ROH59_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDX4804228.1"
                     /translation="MTLDHAALQGLIDHNPARLLKPAMFGASMGKPRERWLPQDELQM
                     LWKALDEAGFGGGSVATGGRGIASSVILSQAIANALRLIILTGVRRSEAVNMRWEQIN
                     GNRWTIPETKNGKSHIVTLHPLALSLLKTQRIISEGGWVFESLSKPSFPVTGDAITRA
                     LERLKTKYMAEVAPFSPHDLRRSIATGCAEYLDAPERLIELLLNHVPKDRLIRTYQVG
                     QQAEKLRNLFLKWGDFIEHEIIESDNGTPDNVIQISFGKR"
     gene            complement(10799..11719)
                     /locus_tag="ROH59_001740"
     CDS             complement(10799..11719)
                     /locus_tag="ROH59_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000365807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HDX4804229.1"
                     /translation="MDLRDSYARQVKLLMAALPHVAKESCFALKGGTAINLFVQDFPR
                     LSVDIDLAYKSFADRDTDLAAINDALKRITASLNGRPGITAIRQENKADEKRIIVNTA
                     DAKIKIEVSPVWRGLLLPPAEMPVCERVEMEYGFTTMSVVSLADLYGGKICAALDRQH
                     PRDLFDVLNMLGRPGLTREIFDGFLCYLAGHPRPIAELLASNWDTDRIATLYAQEFSG
                     MTQQETSLESLLSVTTLLPQALKSHFTDLDREFLLSFKQNSPDWSRYRYPEIQHLPAI
                     RWKQRNLAMLKDKNPAKYVAAVNKLERVLE"
     gene            complement(11706..12488)
                     /locus_tag="ROH59_001741"
     CDS             complement(11706..12488)
                     /locus_tag="ROH59_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HDX4804230.1"
                     /translation="MPNYLNWLMQNTLPGQVLLQSWLTRNGVDRKLSYLYVQNGWLRR
                     IAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLTSLALQGHAHYTEPGKPQVWLAL
                     PAYVKLPGWFAAFEQSATFITLYTSGLTVDVSSFTTELKIGDRQLAGSAPELAAYEIA
                     CGVPSLISFEHADALFQGGNLLSPRKLQALLRASHSIKTNRVMLYLARRNGHPYFQYL
                     DQSGIETGTGKRQIIPGGWLEPDYQITVPRTFKPEGVEDGSA"
     gene            12772..15870
                     /locus_tag="ROH59_001742"
     CDS             12772..15870
                     /locus_tag="ROH59_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001461529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDX4804231.1"
                     /translation="MKFTEDTRVKIPVILHLIRLGYHYLSLKEQRWDKETNIFPDLFT
                     AAIGRINPGLAPDDIGRLLKDLTLLLDNDDLGRAFFEKLSDRSGIKLIDFDNFNNNSF
                     HVVTELTCENGDEEFRPDITLLINGMPLIFIEVKKPNNREGIVAERNRINERFKNPKF
                     KRFANITQFMIFSNNMEYDDSDPEPIQGAFYASSSYSNPVFNYFREEELFNLTNLLKP
                     LSEETEIAVLKDNNLEVIRTNPEFQTNKDHNRPTNRLCTALLSRDRLAFILRYALVYV
                     AEPGGIQKHIMRYPQLFATKAIERKLNAGVKKGIIWHTQGSGKTALAYYNVRFLTDYF
                     QNQQVIPKFYFIVDRLDLLQQAQREFTARGLIVHLIDSREAFTRDIKATQALHNHHGK
                     AEITVVNIQKFRDDPDVVTTKDYDINIQRVYFLDEVHRSYNPKGSFLANLSQSDTNAI
                     KIGLTGTPLLGTDYNSRDLFGDYIHKYYYNASIADGYTLRLIREEIATNYRMILQQAL
                     KEVEVRMGDVDRKYIYAHPSFVKPMLNYIVTDFAKSRGALNDDTIGGMVICDSSEQAK
                     QMFEIFNTDYAESPTAADEVSEEMPVLQAAEPAAVYHLHAKETRKIKRAALILHDIGS
                     KQERKEWVEQFKAGKIDLLFVYNMLLTGFDAKRLKKLYLGRVIRKHNLLQALTRVNRT
                     YNHFRYGYVVDFADIRQEFDATNKAYFEELQAELGDEMEHYSRLFKSAEEIREEIEHI
                     KDVLFSFDTENAEIFTDQINQIQDRETALALKNALADARSLYNLIRLQGNTEFLQALD
                     FNKLNILYREASRRLDLLNLKADLEQGVDLSGLLNRALEEVIFEFHKVGEEELVLADE
                     LKETLRRTREALAANFDQQDPQFVSLKDELERLFKKKKLSEVTQQEMVANIGTLNKIH
                     GRIKELNRQNNLLRQKYRGDVKYARTHKRLRERGGLSEPERKIFEALLSVKLDADEKV
                     LNNSQILNNESYFERHMESCVITHFEDEHHITLTSSAVSDINRLIVAEYLNEFNTGAR
                     TW"
     gene            15864..17501
                     /locus_tag="ROH59_001743"
     CDS             15864..17501
                     /locus_tag="ROH59_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDX4804232.1"
                     /translation="MVELEFRDKTKALIDSLKSICANYGLGNDGNEFKIITQAFLYKF
                     LNDKFAFEAKQKDKSIASAESWEDALSAMSEDQLKKLQQRMAPDTARLKPHHFIRYLY
                     NRQNAADFARTFDDTLMDIAATNNDVFAVKTDGGAKVVLFERLSQYIADESKRDDFCR
                     AIINKLADFSFERIFTQKFDFYATIFEYLIKDYNSNSGGKYAEYYTPHAVARIMAEIL
                     VPKAQQGVVRNVSCYDPSAGSGTLLMNVAHAIGEDRCSIFAQDISQKSSSLLRLNLIL
                     NNLVHSIPNVIQGNTILHPFHKDGGALKRFDYIVSNPPFKMDFSDFRDALDSKENQQR
                     FFAGIPKIKAKARDKMEIYQLFLQHIIFSLKPGGKAAVVVPTGFITAQSGIDKGIREH
                     LVQNKMLAGVVSMPSNIFATTGTNVSILFIDASNKEKVVLIDASNLGEKVKDGKNQKT
                     VLTECEEKRICEAFNNKWSEEDFSVVVSYDDIAAKNYSFSAGQYFDVKIEYTDMTPEQ
                     FAAKMKGFTENLNNLFEQSRELEVQIKMQMADIKYEI"
     gene            17491..18738
                     /locus_tag="ROH59_001744"
     CDS             17491..18738
                     /locus_tag="ROH59_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDX4804233.1"
                     /translation="MKFNYLKIKDVCDFVGGSQPPKSQFIYVSKPGYVRLIQTRDYKT
                     DAFPTYIPISSTKKFCDEFDIMIGRYGPPIFQICRGLKGAYNVALLKVIPKEGVSRDF
                     LYYFLKQDSVFQYVDKLSARTGGQTGVDLVSLKEYPVRIPEEIECQEKLVTILSVIDK
                     KIALNNRINTELEAMAKTLYDYWFVQFDFPDANGKPYKTSGGKMEYNATLKREIPAGW
                     NDSILGKFIELDRGVTYSKEDVRTQDDKDTIGILRATNVTGNNVDIDDLVFIPSSRVN
                     VNQMLNKFDILIVMSSGSKEHVGKNGVYYFEKKHAFGAFCSKITPVRKYRYFINTFLQ
                     SKWFKSYINNQCLGTNINNLTNTHITNCEIICPTPDVVALFENKMMPIYNKLASNTQE
                     NSHLIQLRDWLLPLLMNGQVTVK"
     gene            18918..19103
                     /locus_tag="ROH59_001745"
     CDS             18918..19103
                     /locus_tag="ROH59_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001308408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HDX4804234.1"
                     /translation="MCRAFGYTSMAGRAGASQDAPVSCNAGKANPVRFRPHEISLSSG
                     GHNKPLQETPYGYNPHL"
     gene            19081..19551
                     /locus_tag="ROH59_001746"
     CDS             19081..19551
                     /locus_tag="ROH59_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804235.1"
                     /translation="MATILISDCDLLDLLSAPFNATTDFTVLADYCARFAETLIETDD
                     PALRLALCGRLHAALALLQPTLHDPIPPHLIESLTVDTLPATPEHFISEPDSLCEYCL
                     ALLQLLLERPAEPKTEQTLTGLLCELVWNFTEGLKSPRWLRTADGVKFISEVAA"
     gene            19697..19900
                     /locus_tag="ROH59_001747"
                     /pseudo
     CDS             19697..19900
                     /locus_tag="ROH59_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011579066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(19915..19990)
                     /locus_tag="ROH59_001748"
     tRNA            complement(19915..19990)
                     /locus_tag="ROH59_001748"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19955..19957),aa:Thr,seq:cgt)
     gene            complement(20105..21358)
                     /gene="proA"
                     /locus_tag="ROH59_001749"
     CDS             complement(20105..21358)
                     /gene="proA"
                     /locus_tag="ROH59_001749"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDX4804236.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILN
                     ANAQDVADARANGLSEAMLDRLTLTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALNSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADTAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            complement(21370..22473)
                     /gene="proB"
                     /locus_tag="ROH59_001750"
     CDS             complement(21370..22473)
                     /gene="proB"
                     /locus_tag="ROH59_001750"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDX4804237.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            22762..23817
                     /gene="phoE"
                     /locus_tag="ROH59_001751"
     CDS             22762..23817
                     /gene="phoE"
                     /locus_tag="ROH59_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HDX4804238.1"
                     /translation="MKKSTLALVVMGIVASVSVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPISGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYVDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNLNNDDIVAVGMTYQF"
     gene            complement(23856..24257)
                     /gene="crl"
                     /locus_tag="ROH59_001752"
     CDS             complement(23856..24257)
                     /gene="crl"
                     /locus_tag="ROH59_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDX4804239.1"
                     /translation="MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLRE
                     FHEKLRELLATLNLKLEPADDFRDEPVKLTA"
     gene            complement(24315..25559)
                     /gene="frsA"
                     /locus_tag="ROH59_001753"
     CDS             complement(24315..25559)
                     /gene="frsA"
                     /locus_tag="ROH59_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDX4804240.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFSHGAQLPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILEVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     ALRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            complement(25651..26109)
                     /gene="gpt"
                     /locus_tag="ROH59_001754"
     CDS             complement(25651..26109)
                     /gene="gpt"
                     /locus_tag="ROH59_001754"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDX4804241.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            26370..27827
                     /gene="pepD"
                     /locus_tag="ROH59_001755"
     CDS             26370..27827
                     /gene="pepD"
                     /locus_tag="ROH59_001755"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HDX4804242.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFNLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
                     KSLVDTYQEILKNELAEKEKNLALLLDSVANDKAALTATSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            complement(27883..28497)
                     /locus_tag="ROH59_001756"
     CDS             complement(27883..28497)
                     /locus_tag="ROH59_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HDX4804243.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEATRQDVAVTVLETET
                     GRYSDTLRSALISLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAALKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     gene            complement(28494..29633)
                     /locus_tag="ROH59_001757"
     CDS             complement(28494..29633)
                     /locus_tag="ROH59_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDX4804244.1"
                     /translation="MGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVG
                     MPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILARKYNADKFEKRLSD
                     LDDVAEESWLEENLPSAFAQHPWHNSLGSIGGGNHFAELQQIDQIIDAELFARAGLDA
                     QHLQLLVHSGSRGLGQSILQRHIASFSHHGLPEGSDDALRYIAEHDDALAFARINRQL
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWLVKPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVLAGLIIPVARLRPVLTLKNSGGKKG"
     gene            complement(29823..30275)
                     /locus_tag="ROH59_001758"
     CDS             complement(29823..30275)
                     /locus_tag="ROH59_001758"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX4804245.1"
                     /translation="MNNIQIRNYQPGDFQQLCAIFLRAVTMTASQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAQPVGFITRIGHYIDMLFVEPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGTWFTNFYMRYKPQH"
     gene            complement(30272..31327)
                     /gene="dinB"
                     /locus_tag="ROH59_001759"
     CDS             complement(30272..31327)
                     /gene="dinB"
                     /locus_tag="ROH59_001759"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDX4804246.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPTFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKSDLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            complement(31398..32321)
                     /gene="lafU"
                     /locus_tag="ROH59_001760"
     CDS             complement(31398..32321)
                     /gene="lafU"
                     /locus_tag="ROH59_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HDX4804247.1"
                     /translation="MRKTGNHRERGAKTTIVRRQIKKNHAGHHGGAWKVAFADFTLAM
                     MALFMTLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHPPKPATVAVPEE
                     TEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKD
                     DQNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLS
                     GDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTKSASDT
                     LYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            complement(32324..33187)
                     /gene="motA"
                     /locus_tag="ROH59_001761"
     CDS             complement(32324..33187)
                     /gene="motA"
                     /locus_tag="ROH59_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001169515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HDX4804248.1"
                     /translation="MQKILGLLVVLGCVFGGYFEAGGQLVAIWQPAEMIIILGAGFGA
                     MIIGNPKHVLKEIAHQIKGVISKKQLGPEFQRQLLMCLYELLEMVQNGGLRMLDQHIE
                     QPEESTIFQKYPLVLTQKRLVTFIADNFRLMAMGKIDAHELEGILDQELDTAEESLLT
                     PSRSLQRTAEAMPGFGICAAVLGIIITMQSIDGSIALIGLKVAAALVGTFLGVFICYC
                     LMDPLANAMEQQARAEHSLLECVRTVLVAQAGGKPTLLAVDAGRKLLHLASKPTFANL
                     DAWVNAMLEQE"
     gene            complement(33200..33916)
                     /locus_tag="ROH59_001762"
     CDS             complement(33200..33916)
                     /locus_tag="ROH59_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HDX4804249.1"
                     /translation="MLQDVFESEEFAATLVLTPQQESHYLQAYLPLVRKVVRQLAPQC
                     NCIIDRQDMEQTALMGLLNAIRRYGLPDEGFAGYAVHRIRGAILDELRALDWRPRQLR
                     QKYHQMKDLIRETRKKLGHEPEWQELAEEGISHEDYLEYQQLEGAETLASLDELLNGE
                     GPGIPLAGRELEDQFVTQQMLQHALSQLSEKEQLILSMYYQHEMNLKEIALVLGLTEA
                     RICQLNKQIAQKIRDFVYPN"
     gene            complement(33936..34403)
                     /locus_tag="ROH59_001763"
     CDS             complement(33936..34403)
                     /locus_tag="ROH59_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HDX4804250.1"
                     /translation="MKKIVVAGVVSAVLALVVGAGAGWSVWHHYAGKGKPTTAAQTES
                     VEALDESKSVFVTLPETIVTLHDNNGADHYLSAELVMVVASDKEAEKIKHQEPLYQSI
                     AVECLTEMKFEDLRGMKISAIRKLISDALKKDLQRRKMTAPYKDLLVKKVVFQ"
     gene            complement(34411..35472)
                     /locus_tag="ROH59_001764"
     CDS             complement(34411..35472)
                     /locus_tag="ROH59_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HDX4804251.1"
                     /translation="MNPALLATLGTLAETASLKADILPPVSGENAPVFTLPKMVVAAV
                     AERVHSAKTSQQQATRPQENDPVAMQALMALLLPQPAAPHQDTPQPRNVATSPVIQQL
                     TKAVVQNAPQRPTQQQELTSLPPQLQELIGQLPQAKPEQQARLATYASEDLHAIAPTQ
                     PRVSTPPARPKPELTRVTARPQVERKTEKVPDSEPVIARAVLQVKTPELVSDHQEIVA
                     KPATLSMDELGEKLTTLLKDQIHFQLNKQQQISTIRLDPPSLGKLEIAVQLDNGKLTV
                     HIGANQSEVCRALQQFSDDLRQHLTAQNFMEVNVQVSSEGQSQQQQQSGHQQEEVSAA
                     LQLDDAPQFQQNESVLIKV"
     gene            complement(35469..35780)
                     /locus_tag="ROH59_001765"
     CDS             complement(35469..35780)
                     /locus_tag="ROH59_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDX4804252.1"
                     /translation="MEKQRRQLFALVEAMNDALDKQRWRRLPALYQQLMRQFHDYAAA
                     ETDAAQLDAVKAQLYGAFNALIKRREQRAEVLKARMEQHQRHQEGVLAYSIVNLLSEK
                     S"
     gene            complement(35785..36177)
                     /gene="fliS"
                     /locus_tag="ROH59_001766"
     CDS             complement(35785..36177)
                     /gene="fliS"
                     /locus_tag="ROH59_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDX4804253.1"
                     /translation="MYQVQDGYSQYKEIDLAARTAAASPLELVLVLFSGLMDELERAR
                     SHIEGRRFEKKAQSINKCIDILNALTSSLEFETGGELVVNLSRLYDHCVYRLYEASGE
                     LSAEKIDEVMLILSNLREGWEGLSGKLG"
     gene            complement(36200..37516)
                     /gene="fliD"
                     /locus_tag="ROH59_001767"
     CDS             complement(36200..37516)
                     /gene="fliD"
                     /locus_tag="ROH59_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDX4804254.1"
                     /translation="MINPRTIAQEIAYADVATQATNLQEKQSELDAESSGLDSLSSAL
                     SDFQSAVDALNSDTDGPVTFAATSNNDSATVSANSQAQAGSYSFFVEQLAQGQQTTFS
                     MGDDAFSATGTFELTMGDSTMDIDLSAADQNGDGDGFIDASELVNAINDSDDNPGVSA
                     ALVKTDGTTTIMLTSDSTGAQSAFSVSVTGHDASNDSTSAPVATDVSSAQDAIIHLGS
                     ASGPAITNSSNTFDDVIPGVTMTFTEVSDSDSDLTTFNISEDSSASQEKVQTFVDAYN
                     TLIDTVDSLTTHGDDSSSAGVFAGDAGLSSLANQLDDIAHASYNGVSIVDYGITLDSH
                     GHLQIDSDQFNDAMKSDPDGLTSIFVGDNSMVAQMDDLINTYTDSSNGIITLRQQNID
                     DQMSKIQDEGDQLTDTYNANYDRYLEEYTNTLVEVYTMKASMAAFA"
     gene            complement(37926..38840)
                     /gene="lafA"
                     /locus_tag="ROH59_001768"
     CDS             complement(37926..38840)
                     /gene="lafA"
                     /locus_tag="ROH59_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001570969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lateral flagellin LafA"
                     /protein_id="HDX4804255.1"
                     /translation="MLSINTNNASMAAVNAISKSSSSLSTSMERLATGNRINSSADDA
                     AGKQIANRLTAQSSGMGVALSNINDATAMLQTADSMFDEMSDVLGRMKDLSTQAANGT
                     YSDDDLQAMQDEYDELGQQMSDMLQNTTYGGTNLFGVSGTSNTGTDGLFQSAVTFQVG
                     AESSDTMTVNISSQLNTLVTDLSAISNSFSADQADTTGTAGVSGGTELTASGSANQMI
                     TSISTAMDDVSQIQSKLGASINRLNDTANNLTSMQDNTEVAIGNIMDTDYATEASNMT
                     KQQVLMQTGITMLKQSNSMSSMVSSLLQ"
     gene            39326..40168
                     /locus_tag="ROH59_001769"
     CDS             39326..40168
                     /locus_tag="ROH59_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HDX4804256.1"
                     /translation="MSIIINNWRMDPSLNALIHCETGETRRLGEYHFILLETLAKNAD
                     VVLSRSYLCAEVWKNRIVGGNSLPTAIHALRVAIDDDGKQQNIIKTIPKKGYLCNKEY
                     VSFPESSPAEALIITDQIQKTTPEEISSTTPPVPVRKKHKGLMGLALAAAVILVGSTV
                     GYSHLKSTPDAPQLVKESINSPRIKIFHLSSGKENNSVPLLSQILAPGKDKLDNLLSA
                     HNMTMTTYYKYVRNRLESDIVLRNQCNGSWQLTFNVEGWQNSDINSAMYQNLEKLLNT
                     VQKC"
     gene            complement(40227..41204)
                     /locus_tag="ROH59_001770"
     CDS             complement(40227..41204)
                     /locus_tag="ROH59_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein"
                     /protein_id="HDX4804257.1"
                     /translation="MQVGLTSSSLATGGAHSAAVSSSTVASTQAVRQKLPATASEYPA
                     SPLITTRPQRYSVQLNDQLTTLQQADHYLGQLEQQLLDYRHSQRKGGQAQSTALMQML
                     DKRAALSGGAVDRELQPVLQGEARVTFHSPDLANLVHNPTPGTRMFSVSDGRQTQLSA
                     VMLSEDDSAGQYQTRLTNALRRVGVQVHQQADGISFSTTEKQWPDIERTLSVRTDGDK
                     SAFMPLKTFAEPSQAVRLAQSLQQGGAGISQTLESINQQRAQMAVQQEKARQLIDGMS
                     RFPQTENAVQASENLGGVLDSANHNYQILLQAVNGQARISSQTVRNLLG"
     gene            complement(41221..42150)
                     /gene="flgL"
                     /locus_tag="ROH59_001771"
     CDS             complement(41221..42150)
                     /gene="flgL"
                     /locus_tag="ROH59_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDX4804258.1"
                     /translation="MRVTTQQTYVSMTQSFNNLSGSLAHVVEQMATGKEILQPSDDPI
                     AATRITQLNRQQSAIEQYQSNIDSASAGLSQQESILDGVNNSLLVVRDDLLEAANGTN
                     TADSLASLGQDIESLTDSMVAALNYQDEDGHYVFGGTINDQPPIVAVDDDGDGVTDSY
                     SYQGNSDHRQTTVSNGVEVDTNVAASDFFGSNLDVLNTLNSLSQELQNPDVDPADPQV
                     QSDIQNAVDVVDTASDDLNASIASLGETQNTMSMLSDAQTDISTSNDELIGSLQDLDY
                     GPASITFTGLEVAMEATLKTYSKVSELNLFSVL"
     gene            complement(42165..43541)
                     /gene="flgK"
                     /locus_tag="ROH59_001772"
     CDS             complement(42165..43541)
                     /gene="flgK"
                     /locus_tag="ROH59_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000367241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDX4804259.1"
                     /translation="MDMINIGYSGASTAQVELNVTAQNTANAMTTGYTRQVAEISTIG
                     ASGGSPNSAGNGVQVDSIRRVSNQYQVNQVWYAASDYGYYSTQQGYLTQLEAVLSDDN
                     SSLSGGFDNFFAALNEATTSPDDSALREQVISEAGALSLRIDNTLDYIDSQSTEIISQ
                     QQAMVSQINTLTSGIASYNQQIAQAEANGDNASALYDARDQMVEELSGMMDVQVNIDD
                     QGNYNVTLKNGQPLVSGQQSSTIALETNADGTPTMSLTFAGTTSTMTTDTGGSLGALF
                     DYQNDVLTPLTDTINSMASQFADAVNNQLAQGYDLNGNPGEPLFIYDASNADGPLTVN
                     PDITADELAFSSSPDESGNSDNLQALINISTEPLEIANLGSVTVGQACSSIISNIGIY
                     SQQNQTEVDAASNVYSAAQNQQSSVSGVSMDEEAVNLITYQQIYEANLKVISAGAEIF
                     DSVLEMCS"
     gene            complement(43731..44030)
                     /locus_tag="ROH59_001773"
     CDS             complement(43731..44030)
                     /locus_tag="ROH59_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod-binding protein"
                     /protein_id="HDX4804260.1"
                     /translation="MKVNASGGIDGSDALMGPKVQANDIKQAAEQFEAIFLRNMLKEM
                     RKTNELFDSKDNPFNSDSVRMMQGFYDDELCNTLAQQHGIGIAAMLVKQLSPRHK"
     gene            complement(44030..45130)
                     /locus_tag="ROH59_001774"
     CDS             complement(44030..45130)
                     /locus_tag="ROH59_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HDX4804261.1"
                     /translation="MQNWIKAAAIAVSLTLPGVALAQSLESLVNVQGVRENQLVGYSL
                     VVGLDGTGDKNQVKFTNQTITNMLRQFGVQLPNKIDPKVKNVAAVAVSATLPPMYSRG
                     QTIDVTVSSIGDAKSIRGGTLLLTQLHGADGEVYALAQGSVVVGGMTATGASGSSVTV
                     NTPTAGLIPNGATVEREIPSDFQMGDTITLNLKRPSFKDANNIAAAINASFGGIATAQ
                     SSTNVSVRAPTSPGARVAFMSQLDDVQVQAEKIRARVVFNSRTGTVVMGDGVALHAAA
                     VSHGSLTVSINETSNVSQPNAFAGGRTAVTPQSNIAVNHARPGVVSLPESSSLKTLVN
                     ALNSLGATPDDIMSILQALHEAGALDADLEVI"
     gene            complement(45145..45810)
                     /gene="flgH"
                     /locus_tag="ROH59_001775"
     CDS             complement(45145..45810)
                     /gene="flgH"
                     /locus_tag="ROH59_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002211429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HDX4804262.1"
                     /translation="MKNYLWLVALLPLLSGCESQAILVKKDDAYFAPPTTEAPPPADG
                     RAGGVFETGYNWSLTADRRAYRVGDILTVILEESTQSSKQAKTNFGKSNTVDIGAPTI
                     FGHTKDKLSGSIDANRDFDGSATSQQQNSLRGEITVSVHAVQPNGILEIRGEKWLTLN
                     QGDEYIRLSGLVRADDIQNDNSVSSQRIADARISYAGRGALSDANAAGWLTRLFNHPL
                     FPI"
     gene            complement(45893..46678)
                     /gene="flgG"
                     /locus_tag="ROH59_001776"
     CDS             complement(45893..46678)
                     /gene="flgG"
                     /locus_tag="ROH59_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003838810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HDX4804263.1"
                     /translation="MNAALWISKTGLSAQDAEMSAIANNIANVNTTGFKRDRVMFQDL
                     FYQTQEAPGAMLDQNNIMPTGLQFGSGVRIVGTQKTFTEGNVETTDNAMNVAIMGQGF
                     LQVQKANGDIAYTRDGNLQVNADGVLTNSQGLPLQPEIDVPAGATNVAFGEDGTVTAI
                     LPGDSDVTELGQLTLVNFANPAGLSAEGDNLYLETAASGQPTEGVPGEDGLGTLQDNA
                     LEGSNVDIVNEMVAMITVQRAYEMNAKMVSAADDMLQYISQTL"
     gene            complement(46757..47494)
                     /locus_tag="ROH59_001777"
     CDS             complement(46757..47494)
                     /locus_tag="ROH59_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgF"
                     /protein_id="HDX4804264.1"
                     /translation="MDRLIYTALSGASQTLYEQQISANNLANVNTNGFRADMAMATND
                     KVKGGGFDTRYMAQEGASGVNDSTGVAEKTERPLDVAIQGSGYIAVQDKNGNEVYTRN
                     GNIQQDDQGQLTIDGNLVLGDNGPIILPPNAIASFGSDGTLSVTPDDGDVTATMDIDR
                     LKLVDIPVANLAKNPEGMLVTADGVPAQRDENIKVSGGFLEGSNVSAVSEMMSSIAMN
                     RQFEAQIKMMKTAEDISDAGNRLLRGS"
     gene            complement(47494..48696)
                     /gene="flgE"
                     /locus_tag="ROH59_001778"
     CDS             complement(47494..48696)
                     /gene="flgE"
                     /locus_tag="ROH59_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body protein FlgE"
                     /protein_id="HDX4804265.1"
                     /translation="MSYEIAATGLNAVNEQLDGISNNIANAGTVGYKSMTTQFSAMYA
                     GSQAMGVSVAGTAQSISRGGSLVSTGNALDLAINDDGFFVTCDSAGNISYTRAGSFET
                     DKNGYIVNASGAYLQGYPVDDTGTLQTGTVTDIQIKTGNIPAQASSSLTFTANFDASD
                     AAIDRTTVPFDATNSSSYTDSYTTTVYDSLGNEHSVCQYFTKTSDNTWEVQYTFDGQQ
                     QTGVPATTLTFDPNTGKLTSPTTPQTIEFQTDAAAPIDLTVDYSTCTQYGSEFSVTTN
                     AADGYASATQNGVQVDDDGKVYATYSNGERMLQGQVVLATFPNENGLEAVSGTAWVQT
                     GESGTPLIGVPGSGTCGTLSSGVLESSNVDITSELVNLMTAQRNYQANTKVIATSTQL
                     DDALFQAM"
     gene            complement(48968..49681)
                     /locus_tag="ROH59_001779"
     CDS             complement(48968..49681)
                     /locus_tag="ROH59_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001508388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook capping protein"
                     /protein_id="HDX4804266.1"
                     /translation="MNTLALNAQSPQPTATAESNNVAASDTQSSSDSSPVDTFLTLFV
                     AEIQNQDPTDPTDATEYIDQLSSMAQVAMMEEMSVQANTNAVLMSNIQVMALGNLVGD
                     DIMVQTTALQVSDQTINGRATLDDACTTADLHFTDAAGDDYTVSLIPEGSSSVGPGQV
                     DFSINPADYGIPPGDYDVSVVTNTGEEEVPIEVSGEVEDVRIPLDGSSPVLNVAGVGE
                     VPFTMISQFGVPDADSDVA"
     gene            complement(49681..50112)
                     /gene="flgC"
                     /locus_tag="ROH59_001780"
     CDS             complement(49681..50112)
                     /gene="flgC"
                     /locus_tag="ROH59_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDX4804267.1"
                     /translation="MSFTDIYQISGSAMTAQTLRLNTVASNLANANAPASSEAQAYKA
                     RSPVFAAVYHHSLLAGTHRHAIDGASVQVQDVLQTGGAVKRYEPHSPLADANGDVWYP
                     DVNVVEQMADMMSASRDFETNVDVLNNVKSMQQSLLKLGEA"
     gene            complement(50115..50450)
                     /gene="flgB"
                     /locus_tag="ROH59_001781"
     CDS             complement(50115..50450)
                     /gene="flgB"
                     /locus_tag="ROH59_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005314272.1"
                     /note="with FlgF and C makes up the proximal portion of
                     the flagellar basal body rod; Yersinia has 2 copies of
                     flgB and other flagellar genes; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDX4804268.1"
                     /translation="MGISFQQALGVHPQAVKLRLERTELLTANLANVDTPNFKAKDID
                     FAREMQRANNAAVDVQYRVPMQPSEDGNTVELNSEQARFSQNSMDYQSSLTFLNLQIS
                     GIREAIEGK"
     gene            50532..51269
                     /gene="flgA"
                     /locus_tag="ROH59_001782"
     CDS             50532..51269
                     /gene="flgA"
                     /locus_tag="ROH59_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HDX4804269.1"
                     /translation="MSFQFCRRKFYFLLALALPGYAAVHPVQHSAREQVNAQVLNAAS
                     QKIESLAQQRRWHDYRYTFKVYIPSQIATAAPCTKTPGVTLTSPGDIALNRMNFTVSC
                     PQSWQMNVAVRPDVLVPVVMAKSLVARDTPLTANDVELKPYNVSAQRREVLMEPNDAI
                     GFSSKHALQPGRPITKEELISPVLVERDQPVMIVYQSAGITASMPGVALKNGRKGETV
                     KVRNASSQRVISAMVAESGVVTTVSAE"
     gene            51351..51629
                     /gene="flgM"
                     /locus_tag="ROH59_001783"
     CDS             51351..51629
                     /gene="flgM"
                     /locus_tag="ROH59_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDX4804270.1"
                     /translation="MKITPTMPGNHPTATMAGSSQPRKSTATTATTLSADDITQAGLQ
                     SAQQTLNDQQESDIDSDKVAQMQAMLASGSLQVDTEQLASDMLSFFQN"
     gene            51642..52070
                     /locus_tag="ROH59_001784"
     CDS             51642..52070
                     /locus_tag="ROH59_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDX4804271.1"
                     /translation="MSIRLQQVKALLQGIRDDDALYDSLRELLQRQRICMIRRAREDL
                     LAVNDEITQHYEQLHAHSHQRHSLLKMLGVSVNRDGLAQVFAWLPAVQKAAAQQLWQR
                     LEQKAERCKAYNDKNGELLIRQYEFIQAFLGSEADFLYQG"
     gene            52198..53130
                     /locus_tag="ROH59_001785"
     CDS             52198..53130
                     /locus_tag="ROH59_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-N-methylase"
                     /protein_id="HDX4804272.1"
                     /translation="MSFIECYEPEYVRNFMARHPDSPLYVRKVWKNEIRQSLMLTEPE
                     SCEAVLNDACAFDLQLTYRPVEENAAELSARDAIVNQAILSTLTLPDLTPELYLYAVG
                     IVLSRASKMPGRDGDILARLTTLPQALADHAQKGTLQAQFAQLPPVPQPARQLMTLLG
                     SCAFDWSILPESPRKTSLPLQMPLLTLHDANSKALLQQQLKVQWQTTWQQHFATAPWM
                     MRNWLIYRVYHEVIGQADGADYCPLVCDFYLIRTLISLWTLDGSPLRQEDIFALFAMF
                     ERWRESENAVLIRQQIQAERSADPLLYAFSLLSC"
     gene            53177..55615
                     /locus_tag="ROH59_001786"
     CDS             53177..55615
                     /locus_tag="ROH59_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001773846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDX4804273.1"
                     /translation="MQTLIKTLVTHRVKPFVSVVTPTWNRGAFLPYLLYMYRYQDYPA
                     DRRELIILDDSPQSHQHIIDRLTNGTPESFNIRYIHHPEKLPLGKKRNMLNELARGEY
                     ILCMDDDDYYSPDKISYSIAMMQKHRALISGSDQIPIWYSHINRIFKSRSFGPHNILN
                     GTFCYHRNYLKKHRYDDDCNLGEEKSFTDNFSVNPLQLPGERTILCISHSHNTFDKDF
                     ILGASTPVNAVLTDIVSDPLLRNAYLGLHNATHYQAIHHQAIDQVVLINLDKRPDRLQ
                     QIREELTLLHIPPEKITRLAASENENGQRGRQQSHLQALRLAQQHGWQNYLLLEDDAV
                     ILKQEKHIQVLNALLASLAKIPWQVMILGGEISQGTMLKSLPGLVHARDCRKVCAYLV
                     NSRYYPQLAQQMNNDEHSLEDGWQPLLHTDKWLACYPSLCYQRQGFSDIEKKATDNIN
                     HYFNKLPVATKPSTLPIADTIGFFMETSFHYALYRPIITALQAQGQSCTLVINDRVFK
                     PFLDEMLATLKSIDDPQLKGMRLSEMQAHGQRVKCLVSPYHTPALNGLSTLNIRAMYG
                     LAKETWNHADWNRFYQRILCYSHYSQRALAHFGSAKVVGNPRFDAWHNGTFDRALPEN
                     IQPDSHKPTVLYAPTFGALSSLPHWAEKLGRLSGDVNLMCKLHHGTCSRPEEAASLAL
                     ARRHLKQRTDSARHTLALLAKADYVLTDNSGFIFDAIHVDKRVILLDFPGMTTLLDGE
                     KSYSTPESADQQIREILPVAHDVAELRYLLSEAFDWCAVQGQLAEIRHHYCDAFMDGK
                     AGERAAMVIMEALG"
     gene            56097..56498
                     /locus_tag="ROH59_001787"
     CDS             56097..56498
                     /locus_tag="ROH59_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804274.1"
                     /translation="MLQKIGYMEEDNIIEKKPWRGIPPEYTDRWREIYNNAAPEEGMH
                     LSDACPVCGDTELYRYYSLLKTQPRLLGGIMYKGPGSYWEWCGSCRSYEHMSGYVPIS
                     WVVELSGIDHSKLTAIPDMIDIARHKNHYFS"
BASE COUNT        13839 a        15239 c        14282 g        13388 t
ORIGIN      
        1 aaaaacataa atttaaacct aatcgaaata attaaaactt aatctcgttt aacctatatt
       61 gatatgtgct acgtatctta tttacttccg atttactaaa aaaactgaat gtacctgtaa
      121 aaattacagg tttggaaagt agtgacatgg caaaatgatt acagcaggga ctatgaggtt
      181 aaaaaccata tggaatgtca aaaccgttct gataaataca tctggtctcc ccatgacgcc
      241 tacttctata aaggactatc tgaactgatt gtggatatcg acagattaat ttatctatcg
      301 ctggagaaaa tcagaaaaga tttcgtgttt atcaatctca atacggattc tttaactgag
      361 tttataaacc gtgataatga gtggttatcc gcggtaaagg ggaaacaggt cgtattgatt
      421 gcggccagaa agtcagaagc cttagcaaat tattggtatt acaacagcaa tattaggggc
      481 gtggtatacg ctggactgag tcgtgatatt agaaaagaac tggcctatgt gattaatggc
      541 aggttcctga gaaaagatat taagaaagat aaaatcactg accgggaaat ggaaattatc
      601 cgcatgacgg ctcagggaat gctgcctaaa tcgattgcca gaattgaaaa ttgtagtgtg
      661 aagacagtgt atacccatcg gcgtaatgca gaggccaagc tgtactcaaa attatataag
      721 ttggttcagt aaactccagg caagttagtt ttaaaaaatg actcaccggg acttcatgtc
      781 ctcaattcaa ctcgggaaga aaagcaatga aaaaaaaggt tctggcaata gctctggtaa
      841 cggtgtttac cggtacaggt gtggcgcagg ctgctgacgt aacagctcag gctgtagcga
      901 cctggtcagc aacagccaaa aaagacacca ccagtaagct ggttgtgacg ccactcggta
      961 gcctggcgtt ccagtatgcc gaaggcatta aaggttttaa ctcacaaaaa ggtctatttg
     1021 acgtggctat cgagggtgac tcaacggcta ccgcctttaa actgacctca cgtcttatca
     1081 ccaacacctt aacccagttg gatacctcag gttccacact gaatgtgggc gtggattata
     1141 acggcgcggc agtcgaaaaa actggcgata ccgtgatgat cgataccgcc aacggcgtac
     1201 tgggcggcaa ccttagccca ctggctaacg gttacaatgc cagcaatcgt accactgcac
     1261 aggatggttt cactttctcc atcatcagcg gcaccaccaa tggtaccacc gcagtaaccg
     1321 attacagcac tctaccggaa ggcatctgga gcggcgacgt tagcgtacag ttcgacgcta
     1381 cctggaccag ttaatctctc tgatgtacca gcaggggtac ccccctgctt tattcctgga
     1441 cggaattgtt atgaaaaagc accttctgcc tctcgctctg ctgttttccg gaatatcacc
     1501 ggcccaggcg ctggatgtcg gcgatatatc atcgtttatg aacagtgaca gcagcacgct
     1561 gagcaaaacg atccaaaaca gtaccgacag tggccgcctc atcaatatcc gtctcgaacg
     1621 gctctcttca ccgcttgacg acgggcaggt tatcgcaatg gacaagccgg atgagttgct
     1681 actcactccc gccagcttgc tgctacccgc ccaagccagc gaagtgatcc gcttcttcta
     1741 taagggacca gcagatgaaa aagagcgcta ctaccgcatt gtctggtttg atcaggccct
     1801 cagtgatgcg cagcgcgata atgccaaccg cagcgctgtg gccactgcct ccgcccgcat
     1861 cggcaccatc ctggtcgtcg caccccgcca ggcaaactac cactttcagt acgccaacgg
     1921 ctccctgaca aatacaggaa atgcgacgct gcggatcctc gcctacggcc cctgcctgaa
     1981 agccgccaat ggtaaggagt gtaaagagaa ttactacctg atgccgggca agtcgcgtcg
     2041 ttttacccgc gtggacacgg cggataacaa aggacgggtt gcactttggc agggtgataa
     2101 gttcattccc gtgaaataga tagctgtgca gatggataac gacaatgcct ttacgacggt
     2161 tctccccagg actgaaagcc cagtttgcct tcggcatggt ctttttgttc gttcagcccg
     2221 atgccagcgc tgctgacata agtgcgcagc aaataggtgg ggtgattatt ccgcaggcct
     2281 tcagtcaggc gctccaggac ggcatgagcg tcccgcttta tattcatctc gccggtagcc
     2341 agggtcgcca ggacgatcag cgaatcggca gcgcttttat ctggttggat gatggacagt
     2401 tacgcatccg aaaaatacag ctggaagaga gtgaagataa cgccagtgtc agcgaacaaa
     2461 ctcgacagca gctgatgact ctggccaacg ccccgttcaa tgaggccctt accatccccc
     2521 tgactgacaa cgcgcagttg gatctcagct tgcgccaact gctgctgcag ctggtggtca
     2581 agcgcgaagc gctgggcacc gtactacgct cacgtagcga agacatcggg cagtccagtg
     2641 ttaacaccct cagcagtaat ctgagctata acttcggcgt ctataacaac cagttgcgta
     2701 acggcgggag caacacctcc agctatctgt cgctgaataa cgttactgcg ctgcgcgaac
     2761 atcacgtggt gctcgacggc tcactgtacg ggattggtag cggtcaacag gacagtgaat
     2821 tatataaagc gatgtatgaa cgcgattttg ctggtcaccg atttgccggt ggaatgctcg
     2881 acacctggaa cttgcagtcc ttagggccga tgaccgccat ttcagcaggg aagatttacg
     2941 gcctttcctg gggaaaccag gccagctcca ccatcttcga cagcagccag tcggccacgc
     3001 cagtgatcgc ctttttaccg gcggcgggcg aagtacatct cacccgtgat gggcggctac
     3061 taagcgttca gaacttcacc atgggcaatc atgaagtgga tacccggggt ctaccgtacg
     3121 gtatttacga tgtggaagtt gaggtaatcg ttaacggtcg cgtgatcagc aaacgcaccc
     3181 agcgggtcaa taagctgttt agccgggggc gtggcgtcgg tgcaccgctg gcgtggcaga
     3241 tatggggcgg tagctttcat atggatcgct ggtcggaaaa cgggaaaaag acgcgaccag
     3301 ccaaagagag ttggctggca ggtgcctcga cctccggctc actgagtacg tttagctggg
     3361 cggcaacggg atatggatac gataatcagg cggtgggtga aacccgtctg acgcttccgc
     3421 ttgggggggc gatcaacgtt aacttgcaaa acatgctggc cagtgacagc tcatggagca
     3481 acatcgccag catcagcgcc actctacctg gaggcttcag ttcgctgtgg gttaaccagg
     3541 aaaaaacccg cattggcaat caattgcgac gtagcgatgc cgacaaccgt gcaatcggcg
     3601 gcacactcaa cctgaactca ctgtggtcga agctgggtac gttcagcatc agctacaatg
     3661 atgaccgccg ctacaacagc cactattaca cggcagatta ctatcaaagt gtctacagcg
     3721 gtacctttgg ttcgcttggc ctgcgggccg gtattcagcg ctataacaac ggcgacagca
     3781 gcgccaatac agggaaatat atcgctctcg atctctcgct accactgggc aactggttta
     3841 gcgcagggat gacccatcaa aacggctaca ccatggcaaa cctgtcagca cgcaaacagt
     3901 ttgatgaagg aaccattcgc actgttggtg ccaatctgtc acgagccatc tccggcgata
     3961 ccggtgatga caaaaccctc agcggtgggg cgtatgcaca gttcgacgct cgttacgcca
     4021 gcggaacgct gaacgtcaat agcgcggcgg acggctacat caatactaat ttgaccgcca
     4081 acggcagcgt cggctggcag ggtaaaaaca tcgctgccag cgggcggacc gatggcaacg
     4141 ctggggtgat attcgacact ggcctggaga acgatggtca gatcagcgcc aaaatcaacg
     4201 ggcggatttt cccgcttaac ggcaagcgta actatctccc gctctctccc tatggaagat
     4261 atgaggtgga gttgcagaac agcaaaaact cactcgacag ttacgatatc gtcagcggtc
     4321 gcaaaagtca tctgactctc tatccaggca atgtcgctgt cattgagcca gaggtgaagc
     4381 agatggttac cgtctccggt cgtatccgtg cggaagacgg cacactgctg gctaacgcac
     4441 ggattaacaa ccatatcggc cgaacccgaa ccgatgaaaa cggcgagttt gtcatggacg
     4501 tggataagaa ataccccact atcgattttc gctacagtgg caataaaacc tgcgaagtgg
     4561 cactggaact caaccaggcg cgcggtgccg tctgggtcgg tgatgtggtc tgcagcggcc
     4621 tctcatcgtg ggcggcggtg acgcagacag gagaagagaa tgagagttaa cctactgata
     4681 gcgatgataa tctttgcgct aatctggcct gcaaccgcgc tcagagcggc agtgagcaaa
     4741 acaacctggg cggatgctcc ggcacgcgag tttgtgtttg tcgaaaacaa ctcagacgac
     4801 aactttttcg tcactcctgg cggggcgctg gatccgcgcc tgaccggtgc caaccgctgg
     4861 accggtttaa aatacaatgg ttcaggaacc atctatcagc aaagcctcgg ctacattgat
     4921 aacggttaca acaccggcct ttataccaac tggaagtttg atatgtggct ggaaaattca
     4981 ccagtttcat ctcctttaac tggcttgcgc tgcatcaact ggtacgcagg gtgtaatatg
     5041 accaccagtc ttatcctgcc gcaaaccacc gacgccagtg gattttatgg cgcgacggtg
     5101 accagcggcg gcgcgaagtg gatgcacggc atgttgtcag acgcgtttta ccagtatctg
     5161 caacaaatgc ccgtcggcag cagctttaca atgaccatca atgcctgcca gacctctgtg
     5221 aactatgacg ccagcagcgg cgcacgctgt aaggatcagg cctccggcaa ctggtatgtt
     5281 cgcaacgtca cccatacgaa agcagcaaat ctgcggttga taaataccca ctcgctggcg
     5341 gaagtattta tcaacagcga cggagtaccg actctgggcg aagggaacgc cgactgccgg
     5401 acgcaaacca tcggcagccg ttcaggatta agttgtaaga tggttaacta taccctgcaa
     5461 acaaacggac tcagcaacac ctcaatccat atattcccgg cgatcgccaa ctcgtcgtta
     5521 gcctcggccg tcggggcgta cgatatgcag ttcagtctga atggcagttc atggaaaccg
     5581 gtgagcaata ctgcctatta ctacaccttc aacgagatga agagcgcaga ctcgatctat
     5641 gtgttcttct cgagcaactt ctttaagcag atggtgaacc tcgggatcag cgatatcaac
     5701 accaaagatc tgttcaactt tcgctttcag aacaccacat caccggagtc tggctggtat
     5761 gaattttcta cctccaacac gctgattatc aaaccccgtg atttcagcat cagtattatc
     5821 tccgatgaat atactcagac accgtcgcgg gagggatatg tcggcagcgg cgagtcggca
     5881 ctcgatttcg gctatatcgt aaccaccagc ggtaaaacag ctgccgacga agtgctgatc
     5941 aaggtgaccg gacccgcgca ggtgattggc gggcgctcct attgtgtctt cagctccgat
     6001 gacggtaagg cgaaagtacc gttcccggcg acgctttcct ttattacccg caacggagct
     6061 acaaaaacct acgatgccgg gtgcgatgat agctggcggg atatgaccga tgcgctgtgg
     6121 ttgaccacac cgtggactga tatctctggc gaagtggggc agatggataa gaccacagtc
     6181 aaattttcga ttccaatgga taacgccatt tctctgcgta cggtagatga taacggctgg
     6241 tttggcgaag tcagcgcttc aggagagatt catgttcagg cgacgtggcg taacattaac
     6301 taaggccctg ctgacagtgg tctgtatgct ggcggcacct ttgacacagg cgatttcggt
     6361 cggcaatctg actttttcac tgccgtccga gactgacttt gtcagcaaac gtgtcgtgaa
     6421 taacaacaaa agcgcacgga tataccgtat tgccatcagt gctattgata gcccgggcag
     6481 cagtgaattg cgcacccgac cggtggatgg tgaactactt ttcgcccccc gccagctggc
     6541 gttgcaggct ggtgagagcg agtattttaa attttactat catggcccac gggataaccg
     6601 cgagcgctac taccgggtct catttcgcga ggtccccact cgtaacctga caaaacgcag
     6661 cccaagcggc ggtgaggtca gcacggagcc ggtggtggtg atggatacca ttctggtagt
     6721 acgaccacgt caggttcagt ttaaatggtc cttcgatcag gtgacaggaa cggtaagtaa
     6781 caccggcaac acgtggttta agctactgat taaaccagga tgtgattcga ccgaagagga
     6841 aggcgatgcc tggtatctac gtccgggaga cgtggttcat cagcctgagt tacgtcagcc
     6901 ggggaatcat tatctggtct ataacgacaa attcattaag attagcgatt cctgtccggc
     6961 taagccccct tcggcggact aagacttatc catcggacga gggaagaatt ccacctcaga
     7021 gactcaaaaa tcgtttaaat gatgtggaag cgatcgtcaa tgtcaccgat gagctttctc
     7081 atatgcacac cacagtgttc aggagacacg gaaaggtacc aggcggcctg ctaacgagtg
     7141 gtttcttcac taattaggac gtaaaatcgg taacggctgg aaatcattca atactcacac
     7201 tatcgaaagt acaccagcca accgcgatac gtccctgcat acgacgtacc gcagttatct
     7261 ttacgattta tagctgtact ggtgaattat gagcaatttg aatccatgca tgacgtgtgg
     7321 tgcctgttgt gcatttttcc gcgtctcttt ttactgggcc gaagccgacg atgctggcgg
     7381 taccattccc gccaggctca ctgaacaaat atcccctttt caccgatgca tgagcggtac
     7441 taatcagaaa aatccccgat gtattgccct tgcaggaaca ccgggcaaaa atgcctgctg
     7501 cacgatatat gaaaatcgat cgtccacatg cagagaattc gccatgtctg gtgagaacgg
     7561 agaagtcaat gaggcttgca atcgtgcaag agctaaatac gggctaacac cgttataaat
     7621 atacaataat taattgcatt gccccgccag ctgtaatagc ggggcttcgt ttttcaggga
     7681 caacaaaacc tgaaacttct tccattttcc agcaacaatg cctcttcttc tgtagcgtcc
     7741 tccggatcta catcatcctg aagtagcgcg atatgatcac tgactgtccg catcagaata
     7801 tgaaaagcaa cgtttttaac ctataaaaat ggcgctatat ttgcgccatt tttatcattc
     7861 aaagcattat ctatttgagc ctaaagggat ctcaggatct ggctcatggg taattctgtt
     7921 tcgtaaatct ctgcgaataa tttcaataga ccagaaccag actaaatgtc caaaaatttc
     7981 agagacattc tcataccacg gaagatcaaa gagaggtggc gtaagtccca tgagagggaa
     8041 tgaaatcata tgaacaaaaa gttgcgctaa agcacctgcc agtaagccct gccaaagttt
     8101 aattttcgga aatacttcgg cgaccacaca gtaaccaacg gcaaaaacta tcgaaaagat
     8161 tatgtgcgtt acaccaaccc agttaaagac atgcccggcg aaggtataaa cagccgaatt
     8221 tggatctgtc agtcccaacc aatcccgaag aaaaatgtac ggaggattga gaaagttacg
     8281 ggagcaatca atttggcctg cagccctgat taatgattcc ggaccacacg ctgcattaaa
     8341 catatcaacc ggactacgtg gtggcaatgg aacttctgcc ccccacttaa caaatgcgga
     8401 aacaacgcca gcaatcagcc caatgaatgc agcaagacca taacgtctgc ggtttggtgg
     8461 agtttgttca aatatattca tatctaccct gcttgtacca ttatgttata cacctcttta
     8521 ggagtattca taaaacaagg caaatgtaaa gaactgtatt gttttgtata accacatggt
     8581 tacctaatcg ccaattaata taagctccat tatttctcca tatttttatg ttagaagtga
     8641 caaagagaaa tgtaatgttt ctctcagaga atataaatca ttccttttgc ccaccttaat
     8701 ggtgggcttt tttatgcaaa acctgaacgt cctgtggtat tcctctggca taatgatttt
     8761 cgcgattaac caacaaccag accagcaaag acgccaccac aagcacagta acatccatca
     8821 ggcttgccac accccatgcg tgcggctcaa agccgccatg gcatattaat ccgcttgcca
     8881 ttttcgaaca gctgattggt ttggtccggt gtttccctgc ttgcacttaa aaatgagcgg
     8941 ataggaaact ctcgaaatgg ttcgtcgata tgctcacctc gcacctaatc accttaccga
     9001 acacgcacgg taaatagatt cgatcctgaa cccatcggtc ccaaatctgt cccaatcaaa
     9061 aaataaggaa ggtattaatg atgtgtaact tattgattta agtggtgccg ataataggag
     9121 tcgaacctac gaccttcgca ttacgaaacc aaaaagcatc tatttttccg catatctaca
     9181 cgtctctata aatctcataa aaatattaaa aatcatataa ttaaacaaaa aacccatctt
     9241 atattgttcc atcgaatttc gctctataca atgctaaaca agtacgccag caagtacgcg
     9301 agatgaggcc aaaaatggca atattgataa cccaggacag gcaagtcgca aacctgactc
     9361 cccctgaagg aaaaagtcgg ataaccgtca gcgtcaaatc aaaagtaggt tccggcctgt
     9421 ctgtcgaatc ccgttccggg agtcaaacga agagctggat ttaccgccct tacctcaacg
     9481 gaaaacagat taaaataacg ttaggctcct accctgcaat gacattgtct caggcgcgtg
     9541 aagcacatgc agacgcgctg gcgctggtta aacaaggtat tgatccgcgt tatgcgcgaa
     9601 aaacggaaaa acagcaaaat gaacaaatgc cgattttttc acaattatga aaaaactggc
     9661 tggcattccg tgaaaccaat aaacccattg gggcgcgtac tctggctgat tatgagggaa
     9721 catatcgccg ccatctggag aaaggtttag gttcagtacg cgtctgcgac ctgtccagag
     9781 cctacattta tgaacatctc atacggatca gaaagaccag cgccgaaggt gtccgcaagg
     9841 gacttattct tctcaatatg acgcttgacc atgccgcttt gcagggattg atcgatcaca
     9901 accctgctcg cttgcttaaa cccgcaatgt ttggtgcctc aatgggaaaa ccgcgtgagc
     9961 gttggttgcc acaagacgag ttgcaaatgt tatggaaggc actggatgaa gcggggttcg
    10021 gcggcggatc tgtcgcaacc ggagggcgag gcatcgcgtc cagcgttatt ctttcacaag
    10081 cgattgctaa cgcattacgc ctcatcatcc tgacgggggt gcgacgttcc gaagcggtga
    10141 atatgcgttg ggagcagatt aatggcaacc gctggacaat acctgaaacc aaaaacggta
    10201 aaagtcatat cgtgacgcta catcctctgg cgctttctct attgaagact cagcgcatta
    10261 tttcagaagg cggctgggta ttcgagtcgc tcagtaagcc aagttttcct gtcaccggtg
    10321 acgcaataac tcgtgctctt gaacgcctga aaacaaaata tatggcagaa gtcgctcctt
    10381 tctcaccaca tgatttacgc cgcagcattg ctacaggctg cgctgaatat ctggacgcac
    10441 cagaacggct tatagaactt ctgttaaatc atgtgcccaa agacaggtta atcagaacct
    10501 accaggtcgg gcagcaagcg gaaaaattac ggaatctgtt tctgaaatgg ggggatttta
    10561 ttgagcatga gatcattgag tctgataatg gtactccaga taatgttatt cagatcagct
    10621 ttggaaagag atagtttcgt attttcatga gtagagatcg tctgataact cagcgatctc
    10681 ttactcgatg gtgctatgta ttgaattaaa tgaatatgtt tgagttattg ccacgaagtt
    10741 attcatataa ccaaagcatc atggcccaat tcagagtccc tgaacagcgc taagaatatt
    10801 actccagcac cctctctagc ttattcaccg ccgccacata cttcgccgga tttttatctt
    10861 taagcatcgc cagattgcgt tgcttccagc gaatagccgg aagatgctga atttcaggat
    10921 agcgataccg cgaccagtca gggctgtttt gcttaaaact gagcaagaac tcgcgatcca
    10981 gatccgtaaa atgtgacttc aacgcctgcg gcagcaaagt cgttactgac agaagcgatt
    11041 ccagcgacgt ttcctgctga gtcatccccg aaaattcctg agcgtataac gtggcaatcc
    11101 gatctgtatc ccagtttgaa gccagcaact cggcaatggg acggggatgg cctgccagat
    11161 aacaaagaaa accgtcaaaa atttcgcgcg tcaggcccgg tctccccagc atattcaaca
    11221 catcaaacag atcgcgcgga tgctgacgat caagcgcagc acatatttta ccgccataaa
    11281 gatccgccag cgagacgaca ctcatggtgg tgaagccata ctccatttcc acacgttcgc
    11341 acacaggcat ttctgccgga ggcaacaaca gcccgcgcca gaccgggcta acctcgatct
    11401 taatctttgc atcagcggta ttcacaatga tgcgcttttc atccgcttta ttttcctgcc
    11461 gaatcgcggt gatccccggt ctgccgttca gcgatgcagt aattctcttc aaagcgtcgt
    11521 tgatcgccgc cagatcggta tcgcgatccg caaagctctt atacgccaga tcgatatcca
    11581 ccgatagacg ggggaaatcc tgcacaaata aattgattgc tgtgccgcct ttcaacgcga
    11641 aacaggattc cttcgccaca tgcggcagag cggccatcaa cagtttaacc tgcctggcat
    11701 agctatcacg cagatccatc ttcgactcct tccggtttaa atgtgcgggg aacagtaatt
    11761 tgataatccg gctccagcca gccaccaggt atgatttgcc gctttcccgt acctgtttct
    11821 ataccgcttt gatcaagata ctgaaaataa gggtgtccat tacgccgggc aaggtaaagc
    11881 atcacccggt tggttttaat cgaatgactg gcgcgaagca gtgcctgcaa tttgcgtggg
    11941 ctgagaagat tccccccctg aaacagagca tcggcatgtt cgaacgagat caacgaagga
    12001 acgccgcagg cgatctcata cgcggccagt tccggtgcac tgcctgctaa ctgccggtcg
    12061 ccaattttca gttccgtagt aaatgacgag acatcaacgg taaggcccga tgtatacagc
    12121 gtgataaatg ttgctgattg ttcgaaggca gcaaaccatc ccggcagttt gacgtaagcc
    12181 ggaagcgcga gccagacctg cggcttaccc ggttcggtat agtgcgcatg gccctgaagc
    12241 gcaaggctgg ttagccccgc cacccgaaca ggcttttccc actgtgtttg aaggcagtaa
    12301 accgcgtcta cccaatccgg ctcacggccc gtccggcagt acacaccgtg agcgatgcgc
    12361 ctgagccagc cattctgaac atagagataa gaaagcttac gatctacgcc attgcgggta
    12421 agccatgact ggagcagcac ctgaccgggt agcgtgtttt gcatcaacca gtttagatag
    12481 tttggcaaat gtcgctcctg aatagacatt agtagaaata tttaaaccag tgtaggttca
    12541 gggatacgcc acagcaagaa atagtttaat gattcctcat ttcgtccact taaaatcgac
    12601 attgagcaaa aaatacaaac ttacctacat tcaggcaaag tgcgacaaat agactcggtc
    12661 ggtttaaaga gaacgtgtaa catagatgca aatcgaacag acattgttgc cagccgttcc
    12721 aaggttgtgg ggcgctgcat ggcctgagac gtgataaata cagggaacac aatgaaattc
    12781 actgaagata cccgagtaaa aatccccgtc atcctccacc tgatacggct gggctaccac
    12841 tacctgtccc ttaaagaaca acgctgggac aaagaaacca atatcttccc tgacctcttc
    12901 accgctgcga ttggcagaat aaatcccgga cttgcgccag acgacatcgg acgcctgtta
    12961 aaagacctca cgctgcttct cgacaacgat gatctgggcc gcgccttctt cgaaaaactc
    13021 agtgaccgtt ccggtatcaa actgatcgac tttgataact tcaacaacaa cagtttccat
    13081 gtcgtcaccg aactgacatg cgaaaacggt gatgaagaat tccgcccgga catcacgctg
    13141 ctgatcaacg gcatgccgct aatctttatc gaagtgaaaa aacccaacaa tcgggaaggc
    13201 atcgtcgcag aacgcaaccg catcaacgaa cgctttaaaa accccaaatt caaacgcttc
    13261 gccaacatca cccagttcat gatcttctcc aataacatgg agtatgacga cagcgacccg
    13321 gagccgattc aaggggcatt ctacgccagc agctcttaca gcaacccggt attcaactac
    13381 ttccgcgaag aagaactctt caacctgacc aacttactga aaccgctgtc agaagaaacc
    13441 gaaatcgccg tcctgaaaga caacaacctg gaagtgatcc gcaccaaccc ggaatttcag
    13501 accaacaaag atcacaaccg cccgacaaac cgcctctgca ccgcgctgtt gagccgggat
    13561 cggctggcat ttatcctgcg ctatgcgctg gtgtatgtag ccgaaccggg cggcatccaa
    13621 aaacacatca tgcgctaccc gcagctcttc gccaccaaag cgattgagcg caagctgaac
    13681 gcgggtgtga aaaaaggcat tatctggcac acccagggca gtgggaaaac cgcattggca
    13741 tactacaacg tgcgcttcct gacagattac ttccagaatc agcaggtgat cccgaaattc
    13801 tactttattg tcgatcgtct tgatctgctc cagcaggcgc agcgtgaatt caccgcccgt
    13861 ggcttaatcg ttcaccttat cgactcccgc gaagccttca ctcgcgatat caaagcaacg
    13921 caggcgctgc acaaccacca cggcaaagcg gaaatcaccg tcgtcaacat ccagaaattc
    13981 cgcgatgacc cggatgtcgt caccaccaaa gactacgaca tcaacatcca acgcgtgtac
    14041 ttcctcgatg aagtccaccg cagctacaac cccaaaggga gcttcctggc gaatttaagc
    14101 cagtcggaca ccaacgccat caaaattggc ctgaccggta cgcctctgct gggcacagac
    14161 tacaactccc gcgacctctt cggcgactac atccacaaat actactacaa cgcctccatc
    14221 gccgacggct acacgctgcg cctgatccgc gaagagatcg ccaccaacta ccgaatgatc
    14281 ctgcaacagg cgctaaaaga ggtggaagtc agaatgggcg atgtggatcg caaatacatc
    14341 tacgcccatc ccagctttgt taaaccgatg ctgaactaca tcgtcaccga ctttgccaaa
    14401 agccggggcg cgctgaatga tgacaccatc ggcggcatgg tgatttgcga cagctctgaa
    14461 caggccaagc agatgtttga gatattcaac actgactacg ccgaatcgcc caccgccgcc
    14521 gatgaagtct ccgaagaaat gccggtatta caggccgcag aacctgccgc cgtttaccac
    14581 ctccacgcca aagaaacgcg gaaaatcaaa cgcgccgccc tgatcttgca cgacatcggc
    14641 agcaagcagg agcgcaaaga atgggtggag caattcaaag cgggcaagat tgacctgctg
    14701 ttcgtttaca acatgttgct caccggcttc gacgccaaac ggctgaaaaa actctacctc
    14761 gggcgggtga tcagaaagca caacctgctc caggcgctga cccgcgtcaa ccgtacgtac
    14821 aaccacttcc gctacggcta cgtggtggac ttcgccgaca tccgccagga atttgacgct
    14881 accaacaaag cctacttcga agagctacag gctgaacttg gcgacgaaat ggagcactac
    14941 tcccgcctgt tcaaatcggc ggaagagatc cgcgaagaaa tcgaacacat caaagacgtt
    15001 ctgtttagct tcgataccga aaacgcggaa atcttcactg accagataaa ccagatccag
    15061 gaccgggaaa ccgcgctggc gctaaaaaac gcgctggccg acgcccgcag cctgtacaac
    15121 ctcatccgcc tccagggcaa cactgagttt ctccaggcgc tggatttcaa caaactcaac
    15181 atcctttatc gcgaagccag ccgccgcctc gacttactca acctaaaagc ggatctggaa
    15241 cagggcgttg acctctccgg cctgctgaac cgggcgctgg aagaggtgat ctttgaattc
    15301 cataaagtgg gtgaagaaga gctggtactg gccgacgagc tgaaagagac gctgcgccgc
    15361 acccgcgaag cgctggccgc caacttcgac cagcaggacc cgcagttcgt cagcctgaaa
    15421 gacgaactgg agcgtctgtt taagaaaaag aaactcagcg aagtcaccca gcaagaaatg
    15481 gttgcgaata tcggcacact caataaaatt catggccgca tcaaagagct aaaccgccaa
    15541 aacaacctgc tgcgccagaa ataccggggc gacgtgaaat acgcgcgtac ccacaaacgc
    15601 ctgcgcgagc gcggcggcct gagcgagccg gagcgtaaaa tcttcgaagc actgcttagc
    15661 gttaagctgg atgcagatga aaaagtgctg aacaacagcc agatactgaa caatgaaagc
    15721 tattttgagc ggcatatgga gtcatgcgtc atcacgcact ttgaggatga gcaccatatc
    15781 actctgacct ccagtgcggt aagcgacatc aaccgcctga ttgtggcgga atacctgaac
    15841 gaatttaata ccggagcacg aacgtggtag aactggaatt tagagacaaa accaaagccc
    15901 tgatcgacag cctgaaaagc atctgtgcga actacggcct gggcaacgac ggtaacgaat
    15961 tcaaaattat cactcaggca ttcctgtaca aattcctgaa cgacaaattc gcttttgagg
    16021 ccaaacagaa agataaaagt atcgccagcg ccgaaagctg ggaagatgcg ctcagcgcaa
    16081 tgagcgaaga tcaactgaaa aagctgcaac agcggatggc cccggatacc gcccgcctga
    16141 agccgcacca ttttattcgt tacttgtata accgacaaaa cgcagcggac tttgccagaa
    16201 cttttgacga caccctgatg gacatcgccg ccaccaacaa cgacgtcttc gcggtcaaaa
    16261 ccgacggcgg cgcgaaagtg gtgctgtttg agcgcctcag ccagtacatc gccgacgaat
    16321 caaagcgcga tgatttctgc cgcgccatca tcaacaagct ggccgatttc agcttcgaac
    16381 gcatcttcac gcagaaattc gacttctacg ccaccatctt tgaatacctg atcaaagact
    16441 acaacagcaa ctccggcggc aaatacgcgg aatactacac gccccacgcc gtggcgcgca
    16501 tcatggcgga aatcctggtg ccgaaagcgc agcagggcgt ggtgcgcaac gtaagctgtt
    16561 acgacccgtc cgccggttcc ggcacgctgc tgatgaacgt ggcgcacgcc attggggaag
    16621 atcgttgcag catctttgcc caggatatct cgcagaaatc ctccagcctg ctgcgtctga
    16681 acctgatcct caacaacctg gtgcattcga tccctaacgt tatccagggc aacactattc
    16741 tgcatccgtt ccacaaggac ggcggcgcgc tgaaacgctt tgactacatc gtctccaacc
    16801 cgccgtttaa gatggatttc agcgactttc gtgacgcgct ggacagcaag gaaaaccagc
    16861 aacgtttctt tgccgggata ccgaaaatca aagccaaagc cagggacaaa atggagattt
    16921 accagttgtt cctgcaacac atcattttct cgctgaaacc gggtggcaag gcggcggtcg
    16981 tcgtgccgac cgggtttatc accgcgcaat cgggcattga taaaggcatt cgcgaacatc
    17041 tggtgcaaaa caagatgctg gcgggcgtgg tttccatgcc gtcgaatatc ttcgccacca
    17101 ccggtaccaa cgtgtcgatc ctgtttattg acgccagcaa caaagagaaa gtggtgctga
    17161 tcgacgcctc gaatttaggt gaaaaggtca aagacggcaa aaaccagaaa acggtgctga
    17221 cggagtgcga agaaaaacgg atctgcgaag cgtttaacaa caagtggagc gaagaggatt
    17281 tctcggtggt ggtcagctat gacgacatcg ccgcgaaaaa ttactcgttc agcgccggac
    17341 agtattttga tgtgaaaatc gaatacaccg acatgacgcc ggaacagttt gccgcgaaga
    17401 tgaaaggatt tacggagaat ctgaataatc tctttgaaca gtcgcgcgag ttagaagtgc
    17461 aaataaaaat gcagatggca gatatcaaat atgaaattta attatctgaa aattaaagat
    17521 gtatgtgatt ttgtcggagg aagtcaacct ccaaaatctc aatttattta tgtatctaaa
    17581 cctggatatg tcaggttgat ccagacgcgt gattacaaaa cggatgcatt tcccacgtat
    17641 ataccaatat cgtcgacgaa gaaattttgt gatgaattcg atattatgat tggtaggtat
    17701 ggtcccccaa tttttcaaat atgtcgcgga ttgaaaggag catataacgt tgccttgctg
    17761 aaggttatac ctaaagaagg tgtaagtcgt gattttttat actatttttt gaagcaagac
    17821 tctgttttcc aatatgttga taaattatct gccagaaccg gaggacaaac tggagttgat
    17881 ctagtttctt taaaagaata tccagtcagg atacctgaag aaattgaatg tcaagaaaaa
    17941 ttggtgacta ttcttagtgt tattgataaa aaaatcgccc tcaacaaccg catcaacacg
    18001 gaactggaag cgatggcgaa aacactgtat gactactggt ttgtacagtt tgatttccct
    18061 gatgccaacg gaaaaccgta taaaacctcc ggcgggaaga tggagtataa cgccacgctg
    18121 aaacgggaaa ttccggcagg ttggaatgac tccattcttg gtaagtttat tgagttagat
    18181 cgtggcgtta cttatagcaa agaggatgtt cgaactcagg atgataaaga tacgataggc
    18241 attcttcgcg ctacaaatgt gacgggaaat aatgttgata ttgatgattt agtcttcatt
    18301 ccttctagta gagtaaacgt taatcaaatg ctaaataaat ttgacatatt gatcgtgatg
    18361 tcaagtggta gtaaggagca tgtagggaag aatggcgtgt attatttcga aaaaaaacat
    18421 gcatttggcg cattttgttc aaaaattaca cccgtcagaa aatacagata ttttataaat
    18481 acattcctgc aatcgaaatg gtttaagtct tatataaaca atcagtgctt gggaactaat
    18541 attaataacc tgaccaatac gcatatcact aattgtgaaa tcatatgccc cactcctgat
    18601 gttgtggcgt tattcgagaa taaaatgatg ccaatttata ataaactggc atcaaacact
    18661 caagagaata gtcatttaat ccaactccgc gactggctcc tccctctact tatgaacgga
    18721 caggtcacgg tcaaataatc cccggcgtgg ttttgcgagg cgcattccag atccgcattg
    18781 cgccgcactc accgcagcaa aaccgcttgc cgttcataac cgatcgcagt atctttctcc
    18841 cgcgcctgca aaatcaggcg tcgggattag cctcctgaaa accgttacag gcgacacttg
    18901 acgcaccagc gtcttttttg tgtcgtgcgt tcggctacac ctcaatggcg ggccgggcgg
    18961 gggcgtcgca agacgcgccg gtttcctgta acgccggtaa ggctaacccc gtccggttcc
    19021 gcccccatga gattagcctc tctagtggcg gacataataa accgttacag gagacgccct
    19081 atggctacaa tcctcatctc tgactgcgat ttactcgatc tattgtccgc tcccttcaat
    19141 gccaccacgg atttcaccgt cctggccgac tactgcgccc gcttcgccga aaccctgata
    19201 gaaaccgacg atccggcgct gcggctggcg ctctgcggac ggcttcacgc ggctcttgcg
    19261 ctattgcaac ccacgctgca cgaccccatc ccgccgcatc tgattgaaag cctgaccgtt
    19321 gatacccttc ccgccacacc agagcacttt atttccgaac cagattcctt gtgcgaatac
    19381 tgcctcgcgc tgctccagct actgctggaa cgtccagcag agccaaaaac ggaacaaacc
    19441 ctgaccgggc ttctgtgtga gctggtctgg aatttcacgg aaggactcaa atccccgcgc
    19501 tggctgcgta ccgccgacgg cgtaaaattt atcagtgagg tggccgcatg atgcaacagg
    19561 actgacattc cgccgacatt attgcggtgc tgaaaaagcg gggaacgcct ctggcggcac
    19621 agagaaaaac tcattgcgga agcgctgtaa atatcgccag aaatcatctg gtcctcaagg
    19681 tactttgata gcaaaggcaa gctggctggt tcagtccgga gtctctcttc ttgcacttaa
    19741 agagatggga ggatgggaaa ctcttgaaat ggttcgtcgt taggctcacc tttcagccag
    19801 gcatttcacc gggcacgcga gcaaaatcga tgcgattata agtcgcaatg gcacaaatac
    19861 ggcacaagag gagaacgtgg tgtatttaaa tatggggtaa ctacttgatt ttaatggtgc
    19921 cgataatagg agtcgaacct acgaccttcg cattacgaat gcgctgctct accaactgag
    19981 ctatatcggc cctgaaagga catgttcacg aacgtgaatc acggtggaca aggttaaaac
    20041 taaccgggcg atgcgtcaat ggccttgtga atcaaatggc tacttttgca tcacccggtt
    20101 ttatttacgc acgaatggtg taatcaccaa tgccgatcca cttgtaagtg gtcagtgctt
    20161 ccagccccat tgggccgcgc gcgtggagtt tttgtgtgct taccgccact tccgccccca
    20221 gtccaaactg gccgccgtcg gtaaaacgcg tagaggcgtt aacgtaaaca gcggaggaat
    20281 ccacttcgtt aacaaaacgc tgggcgttgc gcatatcgcg ggtcaggatc gcatcggagt
    20341 gttgcgtgcc gtgttcacga atatgggcaa tggcgtcatc cagatcgcta acgattttga
    20401 cgttcaaatc taatgacaga aactcatcgt catactcttc ggctttaaca gccaccacct
    20461 tcgcggggcc tgcctgcaac tgcgccagcg cggctgtatc agcgtgtaac gtcacgccgc
    20521 tttccgccat ttgtttgctt aatgcgggca ggaagctatc agcgatgttt ttattcacca
    20581 gcaacgtttc taccgtatta cacgtgctcg gacgctgagt tttcgcgttg acaattactt
    20641 tcagggcttc agcgatctct gcgctttcat caacgtaaat atggcatacg cctataccgc
    20701 ctgtgatcac cgggattgtc gactgctcgc ggcacagttt atgcaaacca gccccgccgc
    20761 gcgggatcag catgtcgatg tatttatcca tacgcagcat ttcactgacc agcgcacggt
    20821 caggattatc aatcgcctgc acggcacccg ccggtaagcc acaagagttc agggcgtcct
    20881 gaatcaccgc caccgttgca gcgttagtgc gacacgtttc tttgccgccg cgcaggatca
    20941 ctgcgttacc tgttttcagg cacagcgaag cgacatcaac cgtcacgttc gggcgcgctt
    21001 cataaatcac gccaataacc cccagcggta cgcgacgacg ctcaagacgc aggccgctgt
    21061 ccagtacgcc gccatcgatt acctgcccca ccggatcggc gaggttgcac acctggcgca
    21121 catcatcggc aatgcctttc agccgtgcgg gcgtcagtgt cagacggtca agcatcgctt
    21181 cgctaaggcc attggcacgc gcgtctgcaa catcctgcgc gttagcgttg aggatacttt
    21241 cgctttgtgc ttccagttca tcggcgattt tttccagcac acgatttttt tcgcggctgg
    21301 agagttgcgc taatttatac gaggcttgct tcgcggcaat gcccatttgt tccagcatcg
    21361 gccagctcct taacgggtaa tcatgtcatc acggtgaacg gcaaccgggc cgtattcata
    21421 tcccagtatt gcatcaattt cttgcgagtg gtgtccggca atacggcgta atgcatcgct
    21481 gttgtaacga ctgacgccgt gggcgatatc gcgaccttcg aggttgcaaa tacggatgac
    21541 ttcaccacgc gagaaattgc cagtcacgct tttaatgcct ttcggcaaca gggagctgcc
    21601 gcgttccaga atggcggcag ttgccccttc atctaccgtg atttcacccg caggcggcgc
    21661 accgaaaatc cagcgtttac ggttttcaag cggagtcgcc tgggcatgga acagcgtacc
    21721 gacggaaatg ccttccatca catcaccaat aacgcccggc ttgctgcccg cggcaataat
    21781 ggtgtcgata cccgcacggc aagccacgtc agcggcctgc aatttggtgc tcataccgcc
    21841 agttccgagg cctgaaacgc tatcaccggc aatcgcgcgc agtgcgtcat caatgccgta
    21901 cacatcttta atcagttctg cctgcggatt gctgcgcggg tcagcggtat acaaaccttt
    21961 ttgatcggtc agcagcaaca gtttatcggc acccgccaga atcgccgcca gcgcagaaag
    22021 gttatcgtta tcaccgacct taatctctgc cgtagcgaca gcatcgttct cattaattac
    22081 cggaacgata ttgttatcga gcaacgcacg cagggtatcg cgggcgttca ggaagcgttc
    22141 acgatcttcc atatcagcac gggtcagcaa catctgcccg acatgaatgc cgtaaattga
    22201 aaacagctgt tcccacagtt gaatcagtcg actctgccct accgccgcca gcagctgttt
    22261 tgaagcgata gtcgctggca attccgggta ccccaggtgc tcacgtccgg cggcaatcgc
    22321 acccgacgtc acaataacaa tccgatgccc ggcggcatgt aactgcgcgc actggcgaac
    22381 aagttcaacg atatgggcac ggttcaggcg gcgcgatccg cctgttagca cactggtgcc
    22441 gagttttacc accagcgtct ggctgtcact catgattctc tgccattcaa ttttaggaaa
    22501 aaatgatatc aaacgaacgt tttagcagga ctgtcgtcgg ttgccaacca tctgcgagca
    22561 aagcatggcg ttttgttgcg cgggatcagc aagcgtagcg gcagttgttt acgcttttat
    22621 tacagattta ataaattacc acattttaag aatattatta atctgtaata tatctttaac
    22681 aatctcaggt taaaaacttt cctgttttca acgggactct cccgctgaat attcgcgcgt
    22741 taattaaaat caggaatgaa aatgaaaaag agcactctgg cattagtggt gatgggcatt
    22801 gtggcatctg tatccgtaca ggccgcagaa atatataaca aagacggtaa taaactggat
    22861 gtctatggca aagttaaagc catgcattat atgagtgata atgacagtaa agatggcgac
    22921 cagagttata tccgttttgg ttttaaaggc gaaacacaaa ttaacgatca actgactggt
    22981 tatggtcgtt gggaagctga gtttgccggt aataaagcgg agagtgatac tgcacagcaa
    23041 aaaacgcgtc tcgcttttgc cgggttgaaa tataaagatt tgggttcttt cgattatggt
    23101 cgtaacctgg gcgcgttgta tgacgtggaa gcctggaccg atatgttccc ggaatttggt
    23161 ggcgactcct cggcgcagac cgacaacttt atgaccaaac gcgccagcgg tctggcgacg
    23221 tatcggaaca ccgacttctt cggcgttatc gatggcctga acttaaccct gcaatatcaa
    23281 gggaaaaacg aaaaccgcga cgttaaaaag caaaacggcg atggcttcgg cacgtcattg
    23341 acatatgact ttggtggcag cgatttcgcc atcagtggag cctataccaa ctctgatcgc
    23401 accaacgagc agaacctgca aagccgtggc acaggcaagc gtgcagaagc atgggcaaca
    23461 ggtctgaaat acgatgccaa taatatttat ctggcaactt tctattctga aacacgtaaa
    23521 atgacgccaa tctctggcgg ctttgccaat aagacgcaga actttgaagc ggtcgctcaa
    23581 taccagtttg actttggtct gcgtccatcg ctgggttatg tcttatcgaa agggaaagat
    23641 attgagggca tcggtgatga agatctggtc aattatgtcg atgttggtgc tacgtattat
    23701 ttcaacaaaa atatgtcagc gtttgttgat tataaaatca accaactgga tagcgataac
    23761 aaattgaatc ttaataatga tgatattgtc gcggttggca tgacctatca gttttaatgg
    23821 atattgccgg atgtgatgca tccggcacat ttcattcacg ccgttaactt caccggttca
    23881 tcacgaaaat catctgccgg ttccagcttc agattcagcg tcgccagcag ctcacgcagc
    23941 ttctcgtgaa attcacgcag ggtgtgctcc agtcgttcaa ccacttcggc atcttttatc
    24001 tgaacactcg tccagtcgcc tgctttatcg aacagaccaa actggtaact gtaggtaaaa
    24061 cgggattcct gcgcttccag ttccatccac cagccccaga actcacgcac ttccggtgcc
    24121 ggtttcacgt tgacgcatac agccagacaa tcgaaaaaga atcgattatc ttcgcactta
    24181 ccttcacgaa tatacgggcc tagtgcggta aattttttga ctaatctgct cttcgggtgt
    24241 ccactcggta acgtcattgc aatctcctgt tgtgatgcaa ctgttttacc aaattggtaa
    24301 aatttagcaa atttttaaca caaacgtttt tcgatccagt ctgtgatttc ctgaaggcct
    24361 ttgtcaaaat tccgatacac cgggttaaat gggatctcta ataatttacc gtcagcagat
    24421 gacgacgtga ttaagcgtga gtcctcttcc gggctgaacg gatcgttctt ccagtagcct
    24481 gataacattg gcgttgggca gcgacgtccc agcaaccctt gcacttttaa tgaatagcga
    24541 ttcagctcca cgcgcaacgc ttcgtcagaa gcatcatgca tccccaaacg actcgccaga
    24601 acgtcaagat acatttccgg cacctgttgc tggcacttaa aatcactcaa cagggtatga
    24661 actaccggac caagacaggc aaccgctttc agacgcggcg attcaaggta tgccagacgt
    24721 acggcaacgt tagcgccgaa acggaaacca aaggccgcga cgcgagtgtg atccacccac
    24781 ggtacgttag gcaacgcctt taaaacgtgc tgatgcaaca ggctggagtc ctgggtgagc
    24841 ttccattttg aagaaaagcc caccgacggc atatcaatag tcagcatcgc aatgccgcgc
    24901 agcgcaaaat aacgttcata caggctgtaa tagtctgtct gcatcgcatc cagaccacca
    24961 cacattaata ctgtcgggaa cgggccatcg cctttcggca tatgcaaaaa gccggtgatg
    25021 ggcgcaccgc cgggtacggt aaactccatc tgccgcatcg tgcccggcag acgctgagcg
    25081 gcctcttcat aggcgcggtt tgacaaagcc tgcgcttgct cggccaggtc atctcctttc
    25141 agatgaggat aggcagcaat gttgtacaac gtagccgcat gcagccagtg tcgaccgctg
    25201 agttgcggat cttcttccgc acaggctttt tgttgccaca ccatcgcctg ggtagcccac
    25261 tcataaatcc agttgccgcc gcggtagcca atcaccgtat cgtataaatc atcgtcggta
    25321 cgttcggcat cgctcatcac aatacgcgcc tggacttcga ggatttcacg ggggtcaatg
    25381 ccgcgccaga tccacatcag acggttaatc atgcgatacc agtgagggat ggttttacca
    25441 tcaagggccg actgcacagg cagttgtgcg ccgtgactaa agcggcggac tagcgtcgag
    25501 gtttcaggat gtttaaagcg gggtttgaac agggtttcgc tcaggtttgc ctgtgtcata
    25561 gatgcagcct ccagaatact tactggaaac tattgtaacc cgcctgaagt taaaaagaac
    25621 aacgcccggc agtgccaggc gttgaaaaga ttagcgaccg gagattggcg ggacgaatac
    25681 gacgcccata tcccacggct gttcgatcca ggtattttgc gggatatcaa caacataatc
    25741 atcaaccagc ggacgaccag ccggttttgc gaagatggtg acaaagtgcg cttttggata
    25801 catttcacga atcgcaaccg cagtaccacc ggtatctacc aggtcatcaa taacgatgaa
    25861 gccttcgcca tcgccttctg cgcgtttcag cactttaagc tcgcgctggt tgtcgtgatc
    25921 gtagctggaa atacaaacgg tatcgacatg acgaataccc agttcacgcg ccagtaacgc
    25981 acccggtacc agaccgccac ggcttacggc aataatgcct ttccattgtt cagaaggcat
    26041 cagtcggctt gcgagtttac gtgcatggat ctgcaacatg tcccaggtga cgatgtattt
    26101 ttcgctcatg tgaagtgtcc cagcctgttt atctacggct taaaaagtgt tcgaggggaa
    26161 aataggttgc gcgagattat agagatctgg cgcactaaaa accagtattt cacatgagtc
    26221 cgcgtctttt tacgcactgc ctctccctga cgcgggataa agtggtattc tcaaacatat
    26281 ctcgcaagcc tgtcttgtgt tgacaacatt ttctgctaac cctgtgacct gcaatactgt
    26341 tttgcgggtg atcgacaagg agacttaacg tgtctgaact gtctcaatta tctccacagc
    26401 cgctgtggga tatttttgcc aaaatctgtt ctattcctca cccgtcctat catgaagagc
    26461 aactcgctga atacattgtt ggttgggcaa aagagaaagg tttccatgtc gaacgcgatc
    26521 aggtaggtaa tatcctgatt cgtaaacctg ctaccgcagg tatggaaaat cgtaaaccgg
    26581 tcgtcttgca ggcccacctc gatatggtgc cgcaaaaaaa taacgacacc gtgcatgact
    26641 tcactaaaga tcctatccag ccttatattg atggcgaatg ggttaaagcg cgcggcacca
    26701 cgctgggtgc ggataacggc attggtatgg cctccgcact ggcggttctg gctgacgaaa
    26761 acgtggttca cggcccgctg gaagtgctgc tgaccatgac tgaagaagcc ggtatggacg
    26821 gtgcgttcgg cttacagagc aactggttgc aggctgatat tctgattaac accgactccg
    26881 aagaagaagg tgaaatctac atgggatgtg cggggggtat cgacttcacc tccaacctgc
    26941 atttagatcg tgaagcggtt ccagctggtt ttgaaacctt caatttaacc ttaaaaggtc
    27001 tgaaaggcgg tcactccggc ggtgaaatcc acgttggcct gggtaatgcc aacaaactgc
    27061 tggtgcgctt cctggcgggt catgcagaag aactggacct gcgtcttatt gatttcaacg
    27121 gcggcacact gcgtaacgcc atcccgcgtg aagcctttgc gaccattgct gtcgcagctg
    27181 ataaagtcga cgccctgaaa tctctggtgg atacctatca ggagatcctg aaaaacgaac
    27241 tggcagaaaa agagaagaat ctggcattgc tgctggactc cgtagcgaac gacaaagctg
    27301 cattaacggc gacatctcgc gataccttta ttcgtctgct gaacgccacc ccgaacggag
    27361 ttatccgtaa ttccgatgta gccaaaggcg tggttgaaac ctccctgaac gtcggtgtgg
    27421 tgaccatgac cgacaataac gtagaaattc actgcctgat ccgttctctg atcgacagcg
    27481 gtaaagacta cgtagtgagc atgctggatt cgctgggtaa actggcaggt gcgaaaaccg
    27541 aagcaaaagg cgcatatcct ggctggcagc cggacgctaa ctctccggta atgcatctgg
    27601 tacgtgaaac ctatcagcgt ctgttcaaca agacgccgaa catccagatt atccacgcgg
    27661 gcctggaatg tggtctgttc aaaaaaccgt atccggaaat ggacatggtg tctatcgggc
    27721 caaccatcac cggtccacac tccccggatg agcaagttca tatcgaaagc gttggccatt
    27781 actggacact gctgactgaa ctgctgaaag aaattccggc gaagtaatta tttgatttgc
    27841 tgccggatgg cgtttaacgc cttccggcag tttcatcctt cattatcctt cgataaaagc
    27901 catccctgtg aacgttcgtc gcgggttgcc acgttcaatc tggtgatgga acattcgccg
    27961 ctgcgatttc agcgccgcgc tattttcctg ttgctgttgt tccagcttcc aggcaatcag
    28021 taatcgcgcc agccgtttgt tagcatgctg actgcgctct gactgaacct tcacgctaat
    28081 accggatgcc agatgcgtgg cgcgtaccgc cgagtcggtt ttattgacat gttgaccgcc
    28141 cggccccgac gaacgcagcg tctcataacg gattgcatcc gattgttcct gctcatcagc
    28201 ggtaaaacgc ccaatgccca gaaaccagtt tttgcgccca tgatgaggcc gatacggact
    28261 cggacaaatc cactgaatag tgccgcacca gctttcgctt agagcccatg cgttatcgcc
    28321 atccagagaa atcagcgccg aacgcagtgt gtcagagtag cgacccgttt ctgtttccag
    28381 caccgttacc gcgacgtcct gtcgggtagc ttctttaatc agcctgtcca gtgctttttt
    28441 cactgcgaga caacattctt ccggcccctg agcagaggag agttgtagca agatcatcct
    28501 tttttccctc cactgttttt gagcgtcagc accgggcgca gtcgcgcgac aggaataatt
    28561 aacccagcca gcaccagaca ttgcaccacg ctttcagccg atttataggc ttgtggcgct
    28621 tcttcaaaga tgagttgttt atcgcgacaa attacccgac tgccaagttc agtccgcgag
    28681 agttgcgtcg ccgtgtattt cgctgccaga cgccctttac actcggtgcg cccccattta
    28741 cgccccgccc catgcgccag cgagtggagc gttttttcgt tcgcaacagg tttaaccagc
    28801 caggagtaat cgccgcgtga accgggaata atcaccagac cgttgtcatc cggcgtggcg
    28861 cctttacgat gcaaccagcc ctgttgatcg ccgatttggc acgcgctaac aaagttatgc
    28921 gccacatcca gaaccggact tccggtggcc ttaacttgtt gcattatgcg caaagcgatc
    28981 agctggcgat taatacgcgc aaacgccagc gcatcgtcat gttccgcaat ataccgtagc
    29041 gcgtcgtcac tgccttcagg caaaccatga tgcgaaaacg aggcaatatg ccgctgtaaa
    29101 atagactgcc ccaatcccct cgagccgcta tgaaccagta gttgcagatg ctgcgcatcc
    29161 agaccagccc gtgcaaacag ttccgcgtcg ataatttgat caatctgttg cagttctgcg
    29221 aagtggttac cgccaccgat ggagccaagc gagttgtgcc acggatgctg tgcaaatgct
    29281 gacggcaggt tttcctccag ccagctttct tcagcaacgt catccagatc tgataatcgc
    29341 ttttcaaact tatcggcgtt gtatttgcga gcgagaatat ctgtttgcca tagcgccatg
    29401 ccgcagccga tatcattgcc gaccagtgcc gggtaaaaac gaccaacaga gaagaacgct
    29461 gcgccaatcg ggtagccgcg tccgggatgt aaatctggca tccccacaac gcgctgcatg
    29521 ttgggtaaat ttgccgtggt gtgtaattgt tggatcgcta aactctcgat ccacaggtca
    29581 tcagatgcga tggtaaatac cgcatcggat aagggacgaa tatatttgcc catgtaccat
    29641 tccatttatg aataaaaatc aggaaatggc agacgaatcc agggcaagaa aaaagaatta
    29701 atcctggaaa ggtctgcaaa gagtcattga taaaggattt gtcatgattt acctccttgc
    29761 agtttgtgga ataagaaaac gcgcacatac tagacgggcg ttattttcat tgcaagctgg
    29821 atttaatgtt gcggtttata tcgcatataa aaattagtaa accacgttcc ccggcattca
    29881 acgcgctgct gcttaactgt ctgaaaacca taacgttcaa aaaagggttt tgcggttatg
    29941 ctggcgtcca ccgtaagttc ggattcagac ttaatcaatg gttttaacaa agcgctggca
    30001 actccgcgtc gggtgtattc cggttcaaca aataacatat cgatataatg tccaatgcgg
    30061 gtaataaaac caaccggttg tgcattaata actgcaaccc gcacttgtga tttcgcgagt
    30121 ttctccttcc agcgagattc gtcaatctgc gcccaggcgg caatttgctg tggagaatag
    30181 tgctgactcg ccgtcatcgt aacagctcga aggaaaatag cgcatagttg ctgaaaatca
    30241 ccaggctgat agtttcttat ttgtatgtta ttcataatcc cagcaccagt tgtctttcca
    30301 tttgcgggtc aagcaacgtc acatgcagcc ccaccagtcg cacaccgcgc ccgccgcggc
    30361 gttcatccca ggttttacgc gcggtggcga ttagatcaga tttattcagc cgcggccaga
    30421 cgtgttcctg ggtggtttgc tgaaaatcgt cgaactttaa tttcaccccc tggcgggcaa
    30481 tcagcaaatc aggttttacc tttgccaaac gacgctccag ttcagggtaa agccgctcga
    30541 tgatcgcttc acattcagac cagtgatgaa tatcttccgc catcgtacgt tctacaccga
    30601 cggattttcg caacctttcg ctgttaacgt cgcgttcgtc aatgccctga ctacgctccc
    30661 acaaaatgcg gccaaatttg ccaaagcgtt taagcagcat caccagatca cacttttgca
    30721 catcaccgca ggtccgcagc cccatcgctt ccagttttgc cgccgagact ttgccgacgc
    30781 cgggaatttt tgccagcggt aaggtttgta aaaatgtcgg aacttctgcc ggcgtaatca
    30841 caaactggcc gttgggttta ttcatgtcgg aggcgatttt ggcgagaaac tttactggtg
    30901 ccacgcccgc agacgccgtc agttgcagct cgttgaagat cgtctggcgg atttcctggg
    30961 cgatgagggt cgcagaaccg tggcaatgga cgctatcggt gacatcgaga taggcttcat
    31021 ccagtgataa cggttcaatg cgcgaggtat agcgcgagaa aatttcgcgg atatgatttg
    31081 aggcttcttt gtaggcgtca aagcgccctg gaagcaaggt gagatgcggg cataatttga
    31141 gcgccatccc tgtcggcata gcgctacgta cgccaaattt acgcgcggga taattggcgg
    31201 tgctgatcac cccccgtcgt tcgcggctgc cgccaatagc aatagggata tcgcgcaggg
    31261 cgggattgtc gcgcatctcc accgctgcga aaaagcagtc catatccaca tgaatgattt
    31321 tacgcattgc tcacctctca atactggtaa agtatacagt gatttcaggg tttgagaaat
    31381 gcgtaaagat tcagcattta acgcgttcgc tgcgaaagca cctgctgctt atccagcttt
    31441 tgcaccagcg gctgcaccac tttatcccca tgctgaccaa agtattgata cagcgtatcg
    31501 gacgcacttt tggtcagcac cataatctca atgcgccggt tgcccgcgct ttgcggattt
    31561 ttggcatcca gcagcatctg gtccgccatt gcacttacct gcatcacttt atcttccggc
    31621 attccggcct cttccagcac ccgacgagct gaaagcgcgc gatcgcccga aaggttccag
    31681 ttgttgtaga tattgttttt gtaggccatc gcatcggtat gcccggtaat aataattttg
    31741 ttatcgagcg agtcgaacac tggcgcaagc tccaccagca aagttttaaa gaacggcata
    31801 atcttcgcgc tgccgcgttc gaacatattg cggttctggt cgtctttaat cagcacgcgt
    31861 aatccctggg gaacaatctc catctccaga ttcgcttcca tatgcgcatc acgggcgatg
    31921 gtattgatac tggttgccag ctcgccaagc tcggtggcgg atttcttctt cagcagcgcc
    31981 gttttctcgt tgacgtcgcg cgcttttttc tccgtctctt ccggcaccgc cacggtggca
    32041 ggttttggcg gatgagacgg gctgatttta tttaacggcg acaacccacc accgttaaaa
    32101 atcgactgcc cgtgcagcgc ggcgataatg ctttcacgct cggatttact gacgctgttg
    32161 acaatccaca gcgtcataaa tagcgccatc attgccaaag taaagtcggc gaacgccacc
    32221 ttccacgccc cgccgtgatg cccggcatga ttctttttga tctgccgccg gacgatggtg
    32281 gtttttgccc cacgttcgcg gtggttgccc gtctttctca tgcttattct tgctccagca
    32341 tcgcattcac ccacgcgtcg aggttggcga aggtcggttt ggacgccaga tgcagcagct
    32401 tacgcccggc gtccaccgcc agcagcgtcg gtttgccgcc tgcctgcgcc accagcacag
    32461 tgcgcacgca ttccagcaaa gaatgttccg cccgcgcctg ctgttccatg gcgttggcta
    32521 gcgggtccat caggcagtag cagataaaca cgcctaaaaa cgtccccacc agagccgccg
    32581 ccactttcag gccaatcaga gcgatagatc catcaatcga ctgcatggtg atgatgatgc
    32641 ccagcaccgc cgcgcaaata ccaaatcccg gcatcgcttc ggcggtacgt tgcagcgagc
    32701 gcgacggcgt taacagggac tcttccgcgg tgtccagttc ctgatcgaga atgccttcca
    32761 gctcatgggc gtcgatttta cccatcgcca tcaggcgaaa gttatcagca ataaaggtca
    32821 ccagccgctt ctgggttaac accagcgggt atttctggaa aatggtgctc tcttccggct
    32881 gctcaatatg ctgatccaac atccgcagac cgccgttttg caccatttcg agcaactcat
    32941 acaggcacat taatagctga cgctgaaact ccggcccgag ctgtttttta ctgatcacgc
    33001 ctttaatttg atgggcaatc tctttcagca catgtttcgg gttaccaata atcatcgccc
    33061 cgaaaccggc acccaaaata atgatcattt ccgccggttg ccagatagcc actaattgcc
    33121 cgcccgcttc aaaataaccg ccaaatacgc agccgagcac caccagtaaa cctaatattt
    33181 tttgcatgat ttcttcactt taattcggat agacaaaatc acgaattttc tgcgcgatct
    33241 gtttattcag ttgacaaatt cgggcctcgg ttagccctaa taccagcgca atctctttga
    33301 gattcatctc atgctggtaa tacatggaga ggatcagttg ctctttttcg cttaattgtg
    33361 aaagcgcgtg ttgcaacatt tgctgagtga caaactgatc ttccagttcc cggccagcaa
    33421 gcggaatgcc tggcccttcg ccgttcagca gttcgtccag gctggcgagc gtttccgccc
    33481 cttccagttg ctgatattcg agataatctt catgcgagat cccttcctca gccagctcct
    33541 gccactccgg ttcgtgcccc agttttttac gcgtttcgcg aatcaggtct ttcatctgat
    33601 gatatttctg tcgcagctgg cgcggtcgcc agtcgagagc gcgcagctca tccaggatcg
    33661 caccgcgaat acggtgcacg gcatagcccg caaaaccttc gtccggcagc ccatagcgac
    33721 gaatggcgtt caacagcccc attaacgccg tttgttccat atcctgacgg tcaataatgc
    33781 aattacactg cggggcaagt tgccgcacca ctttacgcac caacggtaaa taggcctgca
    33841 agtagtggct ctcctgctgc ggagttaata ccagcgtggc tgcaaattct tctgactcga
    33901 atacatcctg tagcatgttt atatccgcct ggtgattact ggaagaccac ttttttcacc
    33961 agcaaatcct tatacggtgc ggtcattttg cgacgctgaa gatctttctt taacgcgtca
    34021 gaaatcagtt tgcggatggc agatattttc atgccgcgca aatcttcaaa tttcatttcc
    34081 gtcaggcatt caaccgcaat actttgatac agcggttcct gatgctttat tttttccgcc
    34141 tctttgtcac tggcgaccac catcactaat tccgccgaca aataatgatc cgcgccgttg
    34201 ttgtcatgca aagtgacaat ggtttccggc agcgtcacaa atacgctctt gctctcatcc
    34261 agagcttcca ccgattccgt ttgcgcggcg gtagtcggtt ttccttttcc ggcataatga
    34321 tgccagacac tccatcctgc tccagcgccg accaccaacg ccagaacggc gctgaccacg
    34381 cctgccacca cgattttctt catattgcct ttacactttg atcaaaacgg attcgttctg
    34441 ttgaaattga ggcgcatcat caagctgtaa ggcggcactc acctcttcct gctgatggcc
    34501 cgactgttgt tgctgctgcg actgcccttc ggaggaaacc tgtacgttca cctccataaa
    34561 attttgcgcc gtcagatgct ggcggagatc gtcgctaaac tgctgcaatg cgcggcagac
    34621 ttcgctttga ttcgcaccga tatggaccgt cagtttgccg ttatccaact gtacggcgat
    34681 ctcaagcttg ccaagcgacg gtggatcgag acgaatggtg gagatctgct gttgtttgtt
    34741 gagctgaaag tggatctgat ctttcaacag cgtcgtcagt ttttcgccca gttcgtccat
    34801 cgaaagcgtg gctggtttgg cgacaatctc ctgatgatcg ctgaccaact ctggcgtctt
    34861 aacctgcaac accgcacgcg caataaccgg ttcgctgtcc ggcacttttt ccgttttacg
    34921 ctcgacctgc gggcgcgcgg tcacacgggt tagttcaggt ttcgggcgag ctggcggtgt
    34981 tgagacgcgc ggctgcgtcg gcgcaatggc atgtaaatct tcactggcgt aagtcgccag
    35041 tctggcctgc tgttcgggtt tcgcctgcgg caactgaccg atcagttcct gcaactgcgg
    35101 cggcaacgac gtgagttcct gctgctgcgt cgggcgttgc ggcgcgtttt gcaccaccgc
    35161 tttcgtcaat tgctggataa ccggcgatgt tgcgacgttt cgcggctgcg gcgtgtcctg
    35221 atgcggcgcg gcaggttgcg gaagtaacag cgccattagc gcctgcatcg ccaccggatc
    35281 gttctcctgc gggcgcgtcg cctgttgctg actggtttta gcgctatgaa cgcgctccgc
    35341 caccgccgcg accaccattt tcggcagggt aaacacgggc gcgttttcac cgctcaccgg
    35401 cggtaaaata tccgccttca acgaagcggt ttccgcaagc gttccgagcg tggcaagcaa
    35461 tgccggattc atgacttctc cgaaagtaaa ttaacaattg agtaggccag tacgccttcc
    35521 tgatgccgct gatgctgttc catacgcgct ttcaacactt ctgcgcgctg ctcgcgccgt
    35581 ttaatcaggg cattaaacgc gccgtacagt tgtgccttca ccgcatccaa ctgcgccgcg
    35641 tcggtttccg ccgccgcgta atcgtgaaac tggcgcatca actgctgata cagtgccgga
    35701 aggcgtcgcc agcgttgctt gtcgagggcg tcattcatcg cttcgaccag tgcaaaaagt
    35761 tgcctgcgtt gtttttccat cgtcttaacc cagcttgccc gaaagccctt cccagccttc
    35821 gcgcaggttg cttaagatca gcatcacttc atcgattttc tctgccgaca gttcgccgct
    35881 ggcttcatac aagcgataca cacagtggtc atagaggcgc gaaaggttga ccaccagctc
    35941 gccgccggtt tcaaattcca gcgaactggt gagcgcattg agaatgtcga tgcatttatt
    36001 gatgctctgg gctttcttct cgaaacgccg cccttcaatg tggcttctgg cgcgttccag
    36061 ctcgtccatc aggccagaaa acagcaccag caccagttca agaggcgatg ccgccgcggt
    36121 acgcgccgcg agatcgatct ctttgtattg cgaataaccg tcctgtactt ggtacatctt
    36181 taaggatatt ccttctgaat tacgcaaatg ccgccatact ggctttcatg gtgtacacct
    36241 caaccaacgt attggtgtac tcctcgagat aacggtcgta gttagcgtta taggtatcgg
    36301 taagctgatc gccttcgtcc tgaattttgc tcatctgatc atcaatgttc tgctggcgca
    36361 gggtgatgat gccgttgctg gagtccgtgt aggtgttaat caggtcgtcc atctgcgcca
    36421 ccatgctgtt gtcgccaacg aaaatagagg tcaggccgtc gggatcgctc ttcatcgcgt
    36481 cgttgaactg gtcggagtca atctgtaagt ggccgtgaga atcgagcgtg atgccatagt
    36541 cgacaatcga cacgccgttg tagctggcat gggcgatgtc atcgagctgg tttgccagtg
    36601 agctgagtcc agcatccccc gcaaagaccc cggcgctact actgtcatca ccgtgggtgg
    36661 ttagcgaatc aaccgtatca atcaaggtgt tataggcatc gacaaaggtc tgtactttct
    36721 cctggctggc gctggaatct tcactgatgt taaaggtggt gagatcgctg tcagaatcgc
    36781 tgacttcggt aaaagtcatg gtgacaccgg ggatcacatc atcaaacgtg ttgctgctgt
    36841 tggtgatagc cggtccgctg gcgctaccga gatgaataat cgcgtcctga gcggaggaaa
    36901 catccgtggc aacgggcgca ctggtgctat cgttgctggc atcatgcccc gttacgctca
    36961 ccgaaaacgc gctctgcgcc ccggtgctat cggaggtgag cataatcgtg gtggtgccgt
    37021 cggtttttac cagtgccgcc gacacgcccg gattgtcatc ggagtcgtta atcgcattca
    37081 ccagctcgct ggcgtcgata aaaccgtcac cgtcaccgtt ctgatctgcc gccgacagat
    37141 cgatatccat agtgctgtcg cccatcgtca gttcaaaagt accggtagcg gaaaaggcgt
    37201 cgtcgcccat actgaacgtg gtttgctgcc cctgcgccag ttgctcaacg aaaaacgagt
    37261 agcttcccgc ctgcgcctgg gaattggcgg aaacggtcgc cgagtcatta ttgctggtgg
    37321 cggcaaaagt caccgggccg tcggtatcgc tgttcagcgc gtcaacggcg ctctggaaat
    37381 cgctcaacgc cgagctgagc gagtccaggc cgctgctttc agcatccagc tcactctgct
    37441 tctcctgcaa attcgtcgcc tgagtagcga catccgcata cgcgatttct tgcgcaatgg
    37501 ttcttgggtt gatcattgat gactccggat aacaatgtca ggttattggc aaaaggcgtg
    37561 ccaatatttt ttatgtgaat aatcaataga ttgaaaaaca ggcggaaatg acgtttccgg
    37621 tctggcggaa aaaagcctgc cgcagaaagc acaacaccgc ccacaggcgg tgttgttcgt
    37681 ggccggataa ggcgtttacg ccgcatccgg ctatcggtgc acagtgcctg atgcaacgct
    37741 gacgcgtctt atcaggccta cgagtccgcg cctgttttta tgcgtgtgcc catttgtagg
    37801 ccggataagg cgttcacgcc gcatccggca atcggtgcac aacgcctgat gcgacgctga
    37861 cgcgtcttat caggcctacg agtccgcaca tatttttatg cttgtgcccg tttgtcggcc
    37921 cgaacttact gcagcaggct ggaaaccatg ctggacatgc tgttggactg tttcagcatg
    37981 gtgataccgg tctgcatcag cacctgttgt ttggtcatat tggacgcttc cgtcgcgtaa
    38041 tcggtatcca tgatgttgcc gatagccact tcggtgttgt cctgcatgct ggtcaggttg
    38101 ttggcggtgt cattcagacg gttgatagat gcacccaact tggactgaat ctgagaaacg
    38161 tcatccatcg cggtagaaat gctggtgatc atctggttag ccgagccaga cgcagtcagt
    38221 tcagtaccgc cagaaacgcc tgcggtgcca gtggtgtcag cctgatccgc actaaaggag
    38281 ttgctgatag cagaaaggtc agtcaccagc gtgttcagtt ggcttgaaat gttcacggtc
    38341 atggtgtcgg aagattccgc gcccacctgg aaagttaccg cgctctggaa cagaccgtca
    38401 gtaccggtgt tgctggtgcc ggaaacaccg aacaggttgg tgccgccgta agtagtgttt
    38461 tgcagcatgt cagacatctg ctggcccagt tcgtcgtatt cgtcctgcat cgcctgcagg
    38521 tcgtcgtcgc tgtaggtgcc gttcgctgcc tgcgttgaca ggtctttcat acgccccagc
    38581 acgtcagaca tttcgtcgaa catgctgtca gcggtttgca gcatcgcggt agcatcattg
    38641 atgttgctca gcgccacacc cataccgctg gactgtgccg tcagacggtt agcaatttgt
    38701 ttgcctgcgg cgtcatcggc agaagagtta atccggttac ctgtcgccag gcgttccata
    38761 gaagtagaca gagaagagct gcttttgctg attgcattaa cggcggccat tgaggcgtta
    38821 ttggtgttaa tagataacat gatactgctc cttgggatta atcgtgttcg tttcgatacc
    38881 ctgtaaaaac gacacctcgg gagcaaactt aaaatcgccg ttaaaatttt ttcgccacgt
    38941 attatccgat gccactttta gctaaaaaaa gcagagttta aattcagata aaaagattat
    39001 tagcaatatc tgccacatgg ccaggtatca aaatatgtct ttatcaaatg cttgatatag
    39061 ttaagattgt catcaattaa cgcgttttct tctcaatgta ctgatgccaa aatttacatt
    39121 gcgttgcaaa tagtacacgt ttggctattg tacctgtcct gtcatttcgt tacatttcca
    39181 cgccatatag tgattaagaa taatcctatt accataaaat attaattatc acgcagaaaa
    39241 atcatcttct cagggacgta taagactgtg ctttatgcaa agcactatca ggaaacattt
    39301 atcccttgct aaggtaaact caactatgag tattattatc aacaactggc ggatggaccc
    39361 gtcgcttaat gccttaatac attgcgaaac gggtgaaaca cgtcgtctcg gcgaatacca
    39421 ttttattttg ctggaaacat tagcaaaaaa tgccgatgtg gttttatcgc gatcttattt
    39481 atgtgccgaa gtatggaaga accgcatagt cggcggtaac agcctgccga cggcgatcca
    39541 tgcgttgcgc gttgctatcg atgatgatgg caaacaacag aacattatta aaacaattcc
    39601 gaagaaaggg tacctgtgca ataaagagta tgtgtctttt ccggagtcat cgcctgcgga
    39661 agcgctgatt attaccgacc agatacagaa aacaacgcca gaagagatat cttcgacaac
    39721 accgcctgta cctgttagaa aaaaacataa aggactgatg gggctggcgt tggccgcggc
    39781 tgttatattg gttggctcaa ccgtggggta ttcacacttg aaaagtacac ctgacgcccc
    39841 gcaactggta aaagagtcaa ttaacagtcc aagaataaaa atatttcatc ttagttctgg
    39901 aaaggaaaat aattccgtac cgttactgtc acaaatcctc gcaccaggaa aagacaaact
    39961 cgataattta ttgtcagcgc ataatatgac aatgacaacc tattataaat atgttcgtaa
    40021 ccgactggaa agcgatattg ttctgcgtaa ccagtgcaac ggcagctggc aattaacctt
    40081 taatgtggaa ggttggcaga acagcgatat taatagcgcg atgtatcaga atttagagaa
    40141 gttgttaaat actgtgcaga aatgctgaca agtgccaata tatgccggat gcgacgctaa
    40201 acgcgtctta tccggccaac cgataattat cccaataaat tcctcaccgt ctggctggaa
    40261 attcgcgcct gaccgttcac cgcctgcaat aaaatctgat agttatgatt ggcgctatcc
    40321 agcacgccgc cgaggttctc cgatgcctgc accgcgtttt ccgtttgcgg gaagcgtgac
    40381 atgccgtcga tcaactggcg ggctttttcc tgctgcaccg ccatctgcgc gcgctgctga
    40441 ttaatgcttt ctaacgtctg ggaaatcccc gccccaccct gttgcaaact ttgcgctaaa
    40501 cgcacggcct gcgacggttc ggcaaaggtt tttagtggca taaacgccga cttatcacca
    40561 tcggtgcgca cgcttaaggt gcgctcgatg tcaggccact gtttttcggt ggtggagaaa
    40621 ctgatgccgt ccgcttgctg atgtacctgc acgcccacgc ggcgcagggc gttggtcagg
    40681 cgcgtctggt actgcccggc gctgtcatcc tcagacagca tcaccgccga aagctgggtc
    40741 tgccgcccgt cagagacact gaacatgcgc gttcccggcg tgggattgtg taccagattc
    40801 gccagatccg gcgagtggaa ggtcacccgc gcttcgccct gcaacactgg ttgtaactcg
    40861 cggtccaccg cgccgccgga aagcgcggcg cgtttgtcca gcatctgcat cagcgccgta
    40921 ctctgcgcct gcccgccctt acgctggctg tgacgatagt cgagcaactg ctgttccagt
    40981 tgcccgagat agtgatccgc ctgctgcaac gtggtgagct ggtcgttaag ctgtacgctg
    41041 taacgctgcg ggcgagtggt aatcagcggc gaggccggat attcactcgc cgtcgccggg
    41101 agtttttgcc gcaccgcctg agtggacgca acggttgacg acgataccgc agcgctatgt
    41161 gcgccgccgg tggcgagtga tgaagatgta agtccgacct gcatactgtt cctgaaagag
    41221 ttagagaacg ctgaacaaat tcaactcact cactttcgag taagtcttga gggtagcttc
    41281 cattgccact tccagtccgg taaaggtgat cgacgccgga ccgtaatcga gatcctgcaa
    41341 tgaaccaatc aattcatcat tagatgtcga gatatcggtc tgtgcatcgc tcaacatcga
    41401 catggtgttt tgtgtctcgc cgagcgacgc aatcgaggcg ttgaggtcgt ccgaggcggt
    41461 gtccaccaca tcgacggcgt tctgaatatc gctctgcacc tgcggatctg ccgggtcgac
    41521 gtccgggttt tgcagttcct gcgacaagga attaagcgtg ttaagcacgt ctaaattgct
    41581 accgaaaaaa tcgctcgccg ccacgttggt gtccacttcc acaccgttcg acacggtagt
    41641 ctggcgatgg tcgctgttgc cctgatagct atagctgtcg gtgacgccat cgccatcatc
    41701 gtctaccgcg acaatcggcg gctgatcgtt gatggtgccg ccaaacacgt agtgcccgtc
    41761 ttcgtcctga taattgagcg ccgccaccat tgaatcggtg agcgactcaa tatcctggcc
    41821 gaggcttgcc agcgaatcgg cggtattggt gccgttcgcc gcttcaagca ggtcgtcgcg
    41881 taccaccagc aggctgttgt tgacgccatc gagaatcgat tcctgctggc ttaagcccgc
    41941 cgacgcggag tcgatattgc tctgatactg ttcaatcgcc gactgctggc ggtttaactg
    42001 ggtgatgcgc gtggcggcga ttgggtcatc cgacggctgc aaaatttcct tgccggttgc
    42061 catctgctcg accacatgcg ccagagagcc ggagagatta ttaaaacttt gcgtcatcga
    42121 gacgtaggtt tgttgggtgg ttactcgcat tttcgcgctc ccgcttagct gcacatttcc
    42181 agcaccgaat cgaaaatctc ggccccggcg gaaatgactt tcagattagc ttcataaatt
    42241 tgttgatagg tgatcaggtt caccgcttct tcgtccatgc tgacgccgct gacgctactc
    42301 tgctggtttt gcgctgcgga atagacattg gacgcggcat cgacttccgt ctgattttgc
    42361 tgactgtaaa tgccgatatt gctgatgatt gacgagcacg cctgcccgac cgtcacactg
    42421 ccgaggttgg ctatctccag cggttcggtg gagatattga tcagcgcctg caggttgtcg
    42481 ctgttgccgc tttcgtccgg tgaactggaa aacgccagct catcggcagt gatatccggg
    42541 ttaacggtca gtgggccatc ggcattgctg gcgtcataaa taaacagtgg ctcgccgggg
    42601 ttaccgttga gatcgtagcc ctgcgccagc tggttgttga ccgcatcggc gaactgcgac
    42661 gccatgctgt tgatggtgtc ggtcagcggc gtcagcacgt cgttttgata gtcgaacaga
    42721 gcgcctaacg aaccgccagt gtcggtggtc atggtcgagg tggtgccagc gaaagtcagc
    42781 gacatggtcg gtgtgccgtc ggcgttggtt tccagcgcga tggtcgagct ttgctgcccg
    42841 ctcaccagcg gctgaccgtt tttcagggtg acgttgtagt tgccctggtc gtcaatattg
    42901 acctgcacgt ccatcattcc gctcagttct tccaccatct gatcgcgggc gtcgtacagc
    42961 gcggaggcgt tatcgccgtt ggcttcggcc tgagcgattt gctggttata gctggcgatg
    43021 ccgctggtca gcgtattgat ttgcgatacc atcgcctgct gctgactgat gatttccgtg
    43081 ctttgcgagt cgatgtaatc cagcgtgttg tcgatgcgca acgacagcgc cccggcttcg
    43141 ctgatcacct gctcgcgcag ggcggaatca tcggggctgg tggtcgcttc gttaagggca
    43201 gcgaaaaagt tatcgaagcc gccgctcaga ctgctgttat cgtcgctcag taccgcttcc
    43261 agttgtgtga gatacccttg ttgggtgctg taatagccgt aatcgctggc ggcataccat
    43321 acctgattaa cctgatactg gttggagacg cggcgaatac tgtcgacctg cacgccgtta
    43381 ccagcgctgt tcggcgaacc accgctggca ccgatggtgc tgatctccgc cacctggcgg
    43441 gtgtagcccg tggtcatggc gttagcggtg ttttgcgccg tgacgttcag ctccacctgc
    43501 gccgttgatg cgccgctgta gccgatgtta atcatgtcca tgttgggtcc ttaccggtaa
    43561 atcgtgccgg ttaaaagcgg cgtgaagttg gggattctta agttccgtaa accgggtgcc
    43621 aaatgccgga tgcggcgtaa acgccttatc cggcctacat actacatacg ggcgactcgt
    43681 aggcctgata agacgcgaca gcgtcgcatc aggcaccgaa cgccgaagcc tcatttatgc
    43741 ctgggcgaca actgcttcac aagcatcgcc gcaatcccaa tcccgtgctg ctgcgccagg
    43801 gtgttacaca actcatcgtc ataaaacccc tgcatcatgc gcaccgaatc gctgttaaac
    43861 gggttatctt tcgaatcaaa caactcgttg gttttacgca tctctttcag catgttgcgt
    43921 aaaaaaatcg cctcaaactg ctccgcggcc tgcttaatat cattggcctg aaccttcggc
    43981 cccattaacg catcgctgcc gtcaatcccg ccgctggcgt tcactttcat cagatcacct
    44041 ccaggtcggc atccagcgcg cccgcctcat gcagcgcctg taaaatcgac ataatgtcgt
    44101 ccggcgttgc gcctaaactg ttcagcgcat tgaccagcgt tttcaggctg ctcgactccg
    44161 gcaaactcac cacgcccggg cgcgcatgat tcaccgcgat attgctctgc ggcgttaccg
    44221 ccgtgcgccc gcccgcaaaa gcatttggct ggctgacgtt gctggtttcg ttaatcgaga
    44281 cggtcaaact gccgtgcgac accgccgccg catgcagcgc aacgccatcg cccatcacca
    44341 ccgtgccggt acgcgagtta aacaccacgc gggcgcggat tttctctgcc tgcacctgta
    44401 catcatccag ttgcgacata aatgccaccc gcgcgccggg gctggtgggc gcacgcacgc
    44461 tgacgttggt agagctctgc gcagtagcaa tgccgccaaa cgaggcgtta atcgccgccg
    44521 caatattgtt ggcatcttta aacgacggac gtttcaggtt gagggtgata gtgtcgccca
    44581 tctgaaaatc gctggggatc tcgcgctcta ccgttgcgcc gttaggaatt aacccggcgg
    44641 ttggcgtatt aaccgttacg ctcgaaccgc tggccccggt ggcagtcatc ccgcccacca
    44701 ccacgctgcc ctgcgccagc gcataaactt cgccatccgc gccgtgcaac tgggtcagca
    44761 acaaagtgcc gccacgaata cttttggcat cgccaatcga cgaaacagtg acatcgatgg
    44821 tctgcccgcg cgagtacatc ggcggcagcg tggcgctcac cgctaccgcg gcgacgtttt
    44881 tcaccttcgg atcgatttta tttggcagtt gcacgccaaa ctggcgcagc atattggtga
    44941 tggtctggtt ggtgaatttg acctggtttt tatcaccagt accgtcgagg cctaccacca
    45001 ggctgtagcc gaccagttgg ttttcacgca cgccctgtac gttgaccaac gactccagcg
    45061 attgcgccag cgccacgccg ggcagcgtca gacttacagc gatcgctgcg gcctttatcc
    45121 agttttgcat tgcactctcc ggcattaaat cgggaacaga ggatggttaa acagccgcgt
    45181 caaccagcct gcggcgttgg cgtcgcttaa cgcgccgcgt ccggcatagg agatgcgggc
    45241 atcggcgatc cgctgcgagg aaaccgagtt gtcgttttgg atgtcgtcgg cgcgcaccag
    45301 gccgcttaag cggatgtact catcgccctg gttgagagtc agccattttt cgccgcgaat
    45361 ttccaggatg ccgttaggct gcaccgcatg gacggaaacg gtgatctccc cgcgcaggct
    45421 gttctgctgc tgggaagtgg cgctgccgtc aaagtcgcgg ttggcgtcga tagagccgga
    45481 aagtttatct ttggtgtgtc caaaaatcgt gggcgcgccg atatcgacgg tgttgctttt
    45541 gccgaagttg gttttcgcct gtttgctcga ctgggtggac tcttcgagga tcaccgtcag
    45601 gatatcgccc acgcggtaag cccgccggtc ggcggtgagc gaccagttgt agccggtttc
    45661 aaacacgccc ccggcacgcc cgtctgccgg aggcggcgct tcggtggttg gtggcgcaaa
    45721 gtatgcgtcg tcttttttga ccagaatggc ctgcgattca cacccgctaa ggagtggaag
    45781 cagcgccacc agccagagat aatttttcac gttctgcctg tttaaataca gtgagttatg
    45841 tgctcttgta ggtcggataa gacgcgtcag cgtcgcatcc gacatttcgg ccttacagcg
    45901 tctggctgat gtactgcaac atatcgtccg cagccgagac cattttggcg ttcatctcgt
    45961 acgcccgttg caccgtaatc atcgccacca tctcgttgac gatatccacg ttcgatcctt
    46021 ccagcgcgtt gtcctgcaag gtgccaagcc catcttcgcc cggtacgcct tcggtcggct
    46081 gaccgctggc ggcggtttcc agatagaggt tgtcaccctc agcggaaagc ccggccgggt
    46141 tggcgaagtt caccagcgtc agttgcccta actcagtcac gtcgctgtcg ccgggtaaga
    46201 tcgccgtcac cgtgccatcc tcaccaaaag caacattagt cgcccccgcc ggaacgtcga
    46261 tttccggctg caacggcaag ccctgcgagt tggtcagtac gccgtcagcg ttcacctgca
    46321 agttgccgtc gcgggtataa gcgatatcgc cgttggcctt ttgcacctgc aaaaacccct
    46381 gccccataat ggcgacattc atcgcgttgt cggtggtttc gacgttgcct tcggtgaagg
    46441 ttttctgagt gccgacaatg cgtacgccgc taccgaattg cagcccggtc ggcataatgt
    46501 tgttctgatc gagcatcgcg cccggcgctt cctgggtctg gtaaaacaga tcctgaaaca
    46561 tcacccggtc acgcttgaag ccggtggtgt taacgttggc gatgttgttg gcaatcgcgc
    46621 tcatttcagc atcctgcgcc gagaggccgg ttttgctgat ccatagtgct gcgttcatgg
    46681 tggtaaattc cgtgttattt tttggccgcg gttgccggat gcggcgtgaa cgccttatcc
    46741 ggcctacgat gtgcgattac gagccgcgca ataagcggtt gcccgcgtcg ctgatatctt
    46801 cggcggtttt catcatcttg atctgcgctt cgaactggcg gttcatggcg atggacgaca
    46861 tcatctcgct caccgccgag acgttgctgc cctcgagaaa accgccgctg actttgatgt
    46921 tttcatcgcg ctgggccgga acgccgtcgg cagtcaccag catcccttca ggatttttcg
    46981 ccaggttcgc gaccgggata tccaccagct tcaggcggtc gatatccatc gtcgcggtca
    47041 cgtcaccgtc atcgggcgtc acggagagcg tgccgtcgct gccaaacgaa gcaatggcgt
    47101 tgggcggcag aatgatcggc ccgttatctc ccagcaccag attgccgtcg atagtcagtt
    47161 gcccctggtc atcctgctga atgttgccgt tgcgggtata cacttcgttg ccgtttttat
    47221 cctgcacagc aatgtaaccc gaaccctgaa tcgccacgtc cagtgggcgt tcggttttct
    47281 ccgcaacacc agtgctgtcg ttcacgccgc tggccccttc ctgcgccata tagcgcgtgt
    47341 cgaagccgcc gcctttcacc ttatcgttag tcgccattgc catatcggcg cgaaaaccgt
    47401 tggtgttgac gtttgccagg ttgttggcgc tgatctgctg ctcgtacagg gtctgagaag
    47461 ccccgctcag ggcggtataa atcaagcggt ccattacatt gcctggaaca gcgcgtcatc
    47521 gagctgcgtg ctggtggcga taactttggt gttggcctga tagttacgct gggcggtcat
    47581 caggttgact aactcgctgg tgatatcgac gttagagctt tcgagcacgc ccgacgacag
    47641 cgtgccgcag gtgccggaac cgggaacgcc aatcagcggg gtgccggatt cgccggtttg
    47701 tacccacgcg gtgccgctca ctgcctccag gccgttttca ttcgggaacg tcgccagcac
    47761 cacctgcccc tgcaacatgc gctcgccgtt gctgtaggta gcgtaaactt tgccatcgtc
    47821 atcaacctgc acaccgttct gagtggcaga ggcgtagccg tcggcggcgt tggtggtgac
    47881 cgaaaattca gagccgtatt gcgtacaggt cgagtaatcg acggttaaat cgatgggtgc
    47941 ggcggcgtcg gtctgaaact caatggtctg cggcgtggtt ggcgaggtca gtttcccggt
    48001 gttcgggtcg aaggttaacg tcgtcgccgg aacgccggtc tgctgctgac cgtcgaaggt
    48061 gtactgcact tcccaggtgt tgtcgctggt tttggtgaag tactggcata ccgaatgttc
    48121 gttgcctaat gagtcataca ccgtggtggt gtagctgtcg gtgtacgagc tgctgttggt
    48181 cgcgtcgaac ggtacggtag tgcggtcgat agccgcatcg ctggcatcga agttggcggt
    48241 aaaggtcagg ctgctgctgg cctgcgccgg aatattaccg gttttgatct ggatatcggt
    48301 gactgtaccg gtttgcaggg tgcccgtgtc atcgaccgga tagccctgca aataagcgcc
    48361 cgaggcgttg acgatatagc cgtttttgtc ggtttcaaac gatccggcgc gggtataaga
    48421 aatgttgccc gcgctgtcgc aggtaacaaa aaagccgtcg tcgttaatcg ccagatccag
    48481 cgcgttaccg gtggatacca gcgaaccgcc gcgcgaaata ctttgcgcgg tgcctgccac
    48541 gctgacgccc atcgcctgac ttccggcata catggctgaa aactgggtgg tcatcgactt
    48601 atagcctacc gttccggcgt tggcgatgtt gttactgatc ccgtccagct gttcgttaac
    48661 ggcattcagc cccgttgcag caatttcata actcattgtg tcttcctgtt aattcagatt
    48721 ttggcagcgt gcccgttgtt ttgccggatg cggcgtgaac gccttatccg gcctacgaac
    48781 gggtgcaaac ataaaaatat gcgcgaactc gtaggcctga taagacgcgt taagcgtcgc
    48841 atcaggcatc ttgcaccgaa cgccggatgc ggcgtgaacg ccttatccgg cctacaaaac
    48901 cattcggatt caatagtttc atgtaggcct gataagcgaa gcgcatcagg caatttggca
    48961 ccggacatca cgccacatca ctgtcggcat cgggtacgcc aaactggcta atcatggtga
    49021 acggcacttc gcctacaccg gcaacgttaa gcaccgggga gctgccgtcg agcgggatgc
    49081 gcacatcctc cacttcgccg gaaacttcaa tcggcacctc ttcttccccg gtgttggtga
    49141 ccaccgagac gtcgtaatcg cccggcggga taccgtaatc cgccggatta atcgagaaat
    49201 ccacctgacc tggcccgacg gacgaactgc cttccgggat cagcgacacc gtatagtcat
    49261 cgcctgcggc atcggtaaag tggagatcgg cggtggtaca ggcgtcgtca agcgtggcgc
    49321 gaccattaat ggtctggtcg ctcacctgca aggcggtggt ctgcaccata atgtcgtcac
    49381 ccaccaggtt gccgagcgcc atcacctgaa tgttgctcat cagcaccgcg ttggtgttgg
    49441 cctgcacgct catctcttcc atcatcgcca cctgcgccat cgaagaaagc tggtcgatat
    49501 attcggtggc gtcagtcggg tcggtcgggt cctggttttg gatctcagcg acaaacagcg
    49561 tcaggaaggt atcgacgggc gagctatcgc tgctactttg cgtgtcgctg gccgccacgt
    49621 tgttgctttc cgccgtggcg gtcggctgcg gtgattgcgc attcagcgcc agggtattca
    49681 tcaggcttct cccagtttca gcaaactttg ctgcatactt ttcacgttgt tgagcacatc
    49741 gacattggtt tcgaaatcgc gcgaagccga catcatgtcc gccatctgtt ccaccacgtt
    49801 gacgtcggga taccagacat ccccgttagc atcggcgagc ggcgaatgtg gttcatagcg
    49861 tttcacagct ccgccggttt gcagcacgtc ctgcacctgc acactggcac cgtcaatggc
    49921 atgacgatgt gtacccgcca gcaaactgtg gtgatacacc gccgcaaaca ccgggctgcg
    49981 cgctttatat gcctgcgcct cgctgctggc gggcgcattg gcattcgcca ggttactggc
    50041 aacggtattc agacgcagcg tttgcgccgt catcgccgaa ccggaaatct gatagatatc
    50101 agtaaatgac atgcttattt cccttcaatg gcctctctga tgccgctgat ttgcagattc
    50161 agaaaggtca gactgctttg ataatccata ctattttgtg aaaaccgcgc ttgttcgctg
    50221 ttcagttcca cggtgttgcc atcttccgac ggctgcatcg gcacacggta ctggacatcc
    50281 accgccgcgt tatttgcccg ttgcatctcc ctggcaaaat caatatcttt agccttgaaa
    50341 tttggcgtat cgacgttcgc cagattcgca gtcagtagct cggtcctctc aagacgtaac
    50401 ttcactgcct gcggatgtac tcccaatgcc tgctgaaaac tgatccccat ttcctgcgtc
    50461 actcctgctt caatccgcat acgctaagca atcgccgtgc cattttttaa gtgactgaag
    50521 agaaagggtt tatgagtttt caattttgca ggcggaagtt ttatttcctc ctggcgctgg
    50581 ccttaccggg ctacgccgcc gtccatcccg tgcagcacag cgcgcgggaa caagtcaacg
    50641 cccaggtact gaatgccgcc agccaaaaaa ttgaatcgct ggcgcaacag cggcgctggc
    50701 atgactatcg ctacaccttt aaggtctaca ttccctcgca gattgcgacc gccgcgccct
    50761 gtactaaaac acccggcgtt acgctgactt cgcctgggga catcgccctc aaccggatga
    50821 acttcaccgt cagttgccca caaagctggc agatgaacgt agcggtgcgt ccggatgtac
    50881 tggtgccagt agtaatggcg aagtcactgg ttgcccgcga tacgccgctc accgcgaatg
    50941 atgtggagtt gaagccttac aacgtcagtg cccagcgccg ggaggtgttg atggaaccca
    51001 atgacgcgat tggtttcagc agtaaacacg cgctgcaacc gggcaggcca atcaccaaag
    51061 aagaactgat atctccggtg ctggtcgagc gcgatcaacc ggtgatgatt gtttaccaga
    51121 gcgcggggat caccgcctca atgcccggcg tagcactgaa aaatggtcgc aaaggggaaa
    51181 cggtgaaggt gcgtaacgcc agcagccagc gggtcatcag cgcgatggtg gcggaaagcg
    51241 gcgtggtgac aacggtaagc gcggagtaat ttgcgcgggc gattaaagtt ttgccgcctg
    51301 ttaaccgctt taccggagta acccacccaa aataccgaga cgaggttacg atgaaaatca
    51361 ccccgactat gccaggcaat cacccgacag ccacaatggc aggctccagt cagccgcgca
    51421 aaagcacggc gaccaccgcc acgacgctga gcgccgatga cattacccag gcgggattgc
    51481 agtctgccca gcaaacgctg aacgaccagc aagagagcga tatcgacagc gacaaagtgg
    51541 cacaaatgca ggcgatgcta gcctccggca gcctgcaagt ggacaccgag cagttagcca
    51601 gcgacatgct gagttttttc cagaactaag aggccgatga agtgagtatc cggttacaac
    51661 aggtgaaggc gttgttgcag ggaattcgtg acgacgacgc actgtacgat tccctgcgtg
    51721 aacttctcca gcgtcagcgg atctgcatga ttcgccgcgc cagagaggat ctgctggcgg
    51781 taaacgacga gataacgcag cactatgagc agttgcatgc gcatagccat cagcggcata
    51841 gcctgctgaa aatgctcggt gttagcgtaa atcgtgacgg tctggcgcag gtttttgcct
    51901 ggcttccggc ggtacaaaaa gcggcagcgc aacagttgtg gcaacgcctt gagcaaaaag
    51961 cagaacgctg caaagcctat aacgataaaa acggcgagct gttaattcgc cagtatgaat
    52021 ttattcaggc ttttttaggc agcgaagcgg attttctcta tcagggataa cgacaattcc
    52081 ttcccccatc gcggaaacgg attttccgcc tgatccccaa tcctttgttt ttgattaaaa
    52141 aaattcccgg cacgcttatt gcacatcctg caaggtaata aagactggaa actacctatg
    52201 agttttattg aatgttacga accggaatat gtgcgcaatt ttatggcacg ccaccccgat
    52261 tcgcctttat acgtccgcaa ggtgtggaaa aacgagattc gccagagcct gatgctgaca
    52321 gagccagaaa gctgcgaagc ggtgctcaac gatgcctgcg cctttgattt acagctcacc
    52381 taccgcccgg tggaagaaaa tgccgcagaa ctctccgcgc gcgatgcgat agtaaaccag
    52441 gccattttga gcacccttac gctccccgat ttaaccccgg agctttacct gtatgccgtc
    52501 ggaattgtgc tctcccgcgc cagtaaaatg ccgggcagag atggagatat tcttgcccgc
    52561 ttgacgacgc tgccacaggc gctggccgat catgcacaaa aaggcacgct acaggcacag
    52621 ttcgcccagc tcccgcccgt gccacagccg gcgcgccagt tgatgacgct gctcggcagt
    52681 tgtgcatttg actggtcgat tttgccggaa agcccgcgca aaacttccct gccgttgcaa
    52741 atgcctttgc tgacgctaca tgacgccaac agcaaagccc tgttacaaca gcagcttaag
    52801 gtgcagtggc aaaccacctg gcaacagcat tttgccaccg cgccgtggat gatgcgtaac
    52861 tggctgattt accgcgttta ccatgaggtg attggacagg cagacggcgc agattattgc
    52921 ccgctggtgt gcgattttta tcttatccgc acgttaatca gtttatggac gctggatggt
    52981 tctccgctgc gacaggagga tattttcgcc ctcttcgcca tgtttgaacg ctggcgagag
    53041 agtgaaaatg ccgtgctgat tcgccaacaa attcaggctg aacgttccgc agatcccctg
    53101 ctttatgcgt tttcactgct gtcttgctaa cgctttctgg ccggttttcc cggccttatc
    53161 gacttcgtaa actatcatgc aaaccctcat caaaacactc gtcactcacc gcgtaaaacc
    53221 gtttgtcagc gtcgtcacgc caacctggaa ccgcggcgca ttcctgccgt acctgcttta
    53281 tatgtaccgc tatcaggact acccggcaga ccgccgcgaa ctcatcatcc tcgacgactc
    53341 cccgcaaagc catcaacaca tcatcgaccg cctgaccaat ggcacgccgg aatccttcaa
    53401 catccgctac atccatcacc cggaaaaact gccgctgggc aaaaaacgca atatgctcaa
    53461 cgaactggcg cgcggcgaat acatcctctg catggacgat gacgactact actcgccaga
    53521 taaaatctct tactccatcg ccatgatgca aaaacaccgg gcgctcatct ccggttccga
    53581 ccagatcccc atctggtaca gccacatcaa ccgcattttc aaaagccgca gctttggccc
    53641 acataacatc ctcaatggca ccttttgcta tcaccgtaac tacctgaaaa agcaccgtta
    53701 cgacgacgat tgtaatttag gcgaggagaa aagtttcacc gacaatttca gcgttaaccc
    53761 gctgcaactg cccggcgagc gcacgattct gtgtatctcg cacagccaca acacctttga
    53821 taaagacttt atcctcgggg ccagcacgcc tgtaaacgcg gtgcttacgg atatcgtcag
    53881 cgatccgctg ctacgcaacg cttatctggg tctgcataac gccactcatt atcaggcgat
    53941 ccaccatcag gcgatcgatc aggtcgtatt gatcaatctg gataaacgcc cggatcgctt
    54001 acagcagatc cgtgaagaac tgacattgct gcatattccg cctgagaaga tcacccgcct
    54061 tgccgccagt gaaaatgaaa acggtcaacg gggccgccag caatcacact tgcaggcgct
    54121 gcgtctggcg caacagcacg gctggcaaaa ctacctgttg ctggaagatg acgcggttat
    54181 tctcaaacag gagaaacata ttcaggtgct gaacgcgctg ctggcgagtc tggcgaaaat
    54241 tccctggcag gtgatgatcc tcggcggcga aatttcgcag ggaacgatgc taaaaagttt
    54301 gcctgggctg gtgcacgcgc gggactgccg caaagtgtgc gcttatctgg tgaacagccg
    54361 ctactacccg cagctggcgc agcagatgaa caacgatgag cattcgctgg aagacggctg
    54421 gcagccgctg ctgcacaccg acaaatggct ggcctgttac ccgagccttt gttatcagcg
    54481 acagggcttt agtgatatcg agaaaaaagc gactgataac attaaccact acttcaataa
    54541 gttacccgta gccaccaagc catctacatt acctatcgcc gataccatcg gcttttttat
    54601 ggaaacctca ttccactacg cgctctaccg cccaatcatc accgccctgc aggcgcaggg
    54661 gcagagctgt acgctggtga tcaatgaccg cgtatttaaa ccatttctgg atgaaatgct
    54721 ggcgacgcta aaaagcatcg acgatccgca gctcaaagga atgcgcttat ctgaaatgca
    54781 ggcacacggt cagcgagtga aatgcctggt cagcccctat cacacgcccg cgctcaatgg
    54841 cctttcaacc ctgaacattc gcgccatgta cggcttagcc aaagaaacgt ggaaccacgc
    54901 cgactggaac cgtttttatc agcgcatttt gtgttacagc cactacagcc agcgggcgct
    54961 ggcacatttc ggcagcgcaa aagtggtcgg caatccgcgc ttcgacgcct ggcataacgg
    55021 cacgtttgac cgcgctctgc cggaaaatat ccaacccgat tcccataaac ctacggtgct
    55081 ctacgccccc acgtttggcg cattaagctc cctgccccac tgggcagaaa aattgggccg
    55141 cttaagcggt gatgtgaacc tgatgtgcaa actgcaccac ggcacttgct cgcgcccgga
    55201 agaagctgca tcgctggcac tggcgcgcag gcatttaaaa cagcgcaccg actctgcccg
    55261 ccacacgctg gcgctactgg caaaggccga ttacgtgctg accgataaca gcggctttat
    55321 tttcgatgct attcacgttg ataagcgggt gatcctgctc gactttccgg gcatgacaac
    55381 gttgctcgac ggtgagaaaa gttattccac gcccgaaagt gccgaccagc aaattcgcga
    55441 aatattgccg gtggctcatg atgttgcgga attacgttat ctgctatcag aggcgtttga
    55501 ctggtgtgcg gtacaggggc aactggcgga aattcgtcat cactattgcg atgcgtttat
    55561 ggatggcaag gcgggagaac gggcggcgat ggtgattatg gaggcgctgg ggtaaaccgc
    55621 gcaagtgcct gatgcgcttc gcttatcagg cctacgcgcc cctgcaatat agtgaatttg
    55681 cgatgatttg tcggccggaa aaggcgttta cgccgcatcc ggcacgaaca gtgcacttat
    55741 ctacccttcg atttcaaata catcgcttta tggctggtta atcggtaaaa gttgcacatt
    55801 ttgatagcga gaagagctgt ctttatgaat tccgaaaagc gcccttctac cctctataac
    55861 cattcttttt tacctgtatt ggccgcaaca tacctcaccc acgaagtggt tgtagcaatt
    55921 cgtgggctaa aggtccgcat tatatgaaac gggagggcgg tagcatttct gatattacat
    55981 gcctcaattt tgctgaacta ttggctatcc tggacctcaa aaatctggtc ataagataga
    56041 ttttttaagg gaatacggag taaaggtgtg gaaaactaat taataggttt gtcttaatgc
    56101 ttcagaagat tggatacatg gaagaagata atattataga gaaaaaacca tggcgtggga
    56161 tcccacctga atacacggat agatggaggg aaatttataa caacgctgct cccgaagaag
    56221 ggatgcattt atcagatgct tgtccagtat gtggtgatac ggaattatat cgctattatt
    56281 ctctgttaaa aacgcaacca cgcttattag gagggattat gtataaagga cctggaagtt
    56341 attgggaatg gtgtgggtct tgtcgttcct atgaacatat gtcaggctat gtaccaatat
    56401 cgtgggttgt ggagttatca ggaatagatc attcaaaatt aacggccatt ccagatatga
    56461 ttgatattgc aagacataaa aatcattact tctcttaaat attatctaat tagttttccc
    56521 ggacagggca agttggcgaa aatagtgagg agcatcacgt tttccatcct gactgacacg
    56581 cctactggtg attaaaatca aacctatgga atgacgaaaa agatggaaag gaaaagcata
    56641 tcaagtaatc agtcaggaag atattcacaa caatcacctg aatcagtaga tcgaatgaag
    56701 gatcacttgt cacataatat aattgtcgat atagatctta attcacca
//
LOCUS       DAPOXO010000024        54692 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPOXO010000024 DAPOXO010000000
VERSION     DAPOXO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 54692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54692
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.024"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..175)
                     /locus_tag="ROH59_001788"
     CDS             complement(<1..175)
                     /locus_tag="ROH59_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804275.1"
                     /translation="MKQPDFAKWYFYQLLKSYEGEQMYLNELGYVYGDEEKTKEIVNK
                     LPGYVVKIFEEKID"
     gene            complement(765..1433)
                     /locus_tag="ROH59_001789"
                     /pseudo
     CDS             complement(765..1433)
                     /locus_tag="ROH59_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313257.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1556..2008)
                     /gene="tabA"
                     /locus_tag="ROH59_001790"
     CDS             complement(1556..2008)
                     /gene="tabA"
                     /locus_tag="ROH59_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin biofilm protein TabA"
                     /protein_id="HDX4804276.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRL
                     FYLISEDMTEPYKARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPETDWLVDKDIAF
                     LPEVVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA"
     gene            complement(2153..2746)
                     /locus_tag="ROH59_001791"
     CDS             complement(2153..2746)
                     /locus_tag="ROH59_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313255.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX4804277.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLAEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSLEQLCATAALAGEAIKTILKE"
     gene            2817..3530
                     /gene="bdcA"
                     /locus_tag="ROH59_001792"
     CDS             2817..3530
                     /gene="bdcA"
                     /locus_tag="ROH59_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4804278.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAA
                     ERLAHETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            3661..4056
                     /locus_tag="ROH59_001793"
     CDS             3661..4056
                     /locus_tag="ROH59_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDX4804279.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPEKQFEDIMTVKNEIFSAP
                     PYPNWTAVGVTWLAGFDFEIKVIARIPEL"
     gene            4337..4471
                     /gene="pyrL"
                     /locus_tag="ROH59_001794"
     CDS             4337..4471
                     /gene="pyrL"
                     /locus_tag="ROH59_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HDX4804280.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            4475..5410
                     /gene="pyrB"
                     /locus_tag="ROH59_001795"
     CDS             4475..5410
                     /gene="pyrB"
                     /locus_tag="ROH59_001795"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDX4804281.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            5423..5884
                     /gene="pyrI"
                     /locus_tag="ROH59_001796"
     CDS             5423..5884
                     /gene="pyrI"
                     /locus_tag="ROH59_001796"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HDX4804282.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            5957..6343
                     /gene="ridA"
                     /locus_tag="ROH59_001797"
     CDS             5957..6343
                     /gene="ridA"
                     /locus_tag="ROH59_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HDX4804283.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(6549..9245)
                     /gene="mgtA"
                     /locus_tag="ROH59_001798"
     CDS             complement(6549..9245)
                     /gene="mgtA"
                     /locus_tag="ROH59_001798"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDX4804284.1"
                     /translation="MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTAVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(9386..9439)
                     /gene="mgtL"
                     /locus_tag="ROH59_001799"
     CDS             complement(9386..9439)
                     /gene="mgtL"
                     /locus_tag="ROH59_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HDX4804285.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            9624..10571
                     /gene="treR"
                     /locus_tag="ROH59_001800"
     CDS             9624..10571
                     /gene="treR"
                     /locus_tag="ROH59_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HDX4804286.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            10690..12111
                     /gene="treB"
                     /locus_tag="ROH59_001801"
     CDS             10690..12111
                     /gene="treB"
                     /locus_tag="ROH59_001801"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HDX4804287.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGNFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            12161..13816
                     /gene="treC"
                     /locus_tag="ROH59_001802"
     CDS             12161..13816
                     /gene="treC"
                     /locus_tag="ROH59_001802"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDX4804288.1"
                     /translation="MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHK
                     LGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR
                     NDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALA
                     DESSVFYTYQKLIALRKQEAILTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRE
                     IQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK"
     gene            14210..16348
                     /gene="nrdD"
                     /locus_tag="ROH59_001803"
     CDS             14210..16348
                     /gene="nrdD"
                     /locus_tag="ROH59_001803"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDX4804289.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWSIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            16507..16971
                     /gene="nrdG"
                     /locus_tag="ROH59_001804"
     CDS             16507..16971
                     /gene="nrdG"
                     /locus_tag="ROH59_001804"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HDX4804290.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QTFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVKRIRAECPGKDIW
                     VWTGYKLDELNAAQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR"
     gene            complement(17016..17402)
                     /gene="cybC"
                     /locus_tag="ROH59_001805"
     CDS             complement(17016..17402)
                     /gene="cybC"
                     /locus_tag="ROH59_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HDX4804291.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVIEKADN
                     AAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNAYHQKYR"
     gene            complement(17585..18937)
                     /gene="pmbA"
                     /locus_tag="ROH59_001806"
     CDS             complement(17585..18937)
                     /gene="pmbA"
                     /locus_tag="ROH59_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HDX4804292.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFL
                     LDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            19031..19582
                     /locus_tag="ROH59_001807"
     CDS             19031..19582
                     /locus_tag="ROH59_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HDX4804293.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            complement(19733..21106)
                     /gene="mpl"
                     /locus_tag="ROH59_001808"
     CDS             complement(19733..21106)
                     /gene="mpl"
                     /locus_tag="ROH59_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HDX4804294.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            21282..22280
                     /gene="fbp"
                     /locus_tag="ROH59_001809"
     CDS             21282..22280
                     /gene="fbp"
                     /locus_tag="ROH59_001809"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HDX4804295.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA"
     gene            complement(22313..23308)
                     /gene="yjfF"
                     /locus_tag="ROH59_001810"
     CDS             complement(22313..23308)
                     /gene="yjfF"
                     /locus_tag="ROH59_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease YjfF"
                     /protein_id="HDX4804296.1"
                     /translation="MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPIYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQR"
     gene            complement(23295..24317)
                     /locus_tag="ROH59_001811"
     CDS             complement(23295..24317)
                     /locus_tag="ROH59_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804297.1"
                     /translation="MPQSLPDTTPPKRRFRWPTGMPQLAALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITAGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVLTLLLFWLLTRKTALGMFIEAVGINIRAAKNAG
                     VNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RSHDKT"
     gene            complement(24331..25833)
                     /locus_tag="ROH59_001812"
     CDS             complement(24331..25833)
                     /locus_tag="ROH59_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDX4804298.1"
                     /translation="MTTDQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGEN
                     GAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFGLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVL
                     RNGSFVGCRETRELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKPQTLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            complement(25973..26929)
                     /gene="ytfQ"
                     /locus_tag="ROH59_001813"
     CDS             complement(25973..26929)
                     /gene="ytfQ"
                     /locus_tag="ROH59_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HDX4804299.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            27239..27769
                     /gene="ppa"
                     /locus_tag="ROH59_001814"
     CDS             27239..27769
                     /gene="ppa"
                     /locus_tag="ROH59_001814"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HDX4804300.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLVAVPHSKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            complement(27849..28199)
                     /gene="chpB"
                     /locus_tag="ROH59_001815"
     CDS             complement(27849..28199)
                     /gene="chpB"
                     /locus_tag="ROH59_001815"
                     /EC_number="4.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease toxin ChpB"
                     /protein_id="HDX4804301.1"
                     /translation="MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLG
                     MTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAADE
                     VVEEALLRLQAVVE"
     gene            complement(28193..28444)
                     /gene="chpS"
                     /locus_tag="ROH59_001816"
     CDS             complement(28193..28444)
                     /gene="chpS"
                     /locus_tag="ROH59_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin ChpS"
                     /protein_id="HDX4804302.1"
                     /translation="MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILT
                     PISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGDEIW"
     gene            complement(28656..28997)
                     /locus_tag="ROH59_001817"
     CDS             complement(28656..28997)
                     /locus_tag="ROH59_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HDX4804303.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            complement(29000..32779)
                     /gene="tamB"
                     /locus_tag="ROH59_001818"
     CDS             complement(29000..32779)
                     /gene="tamB"
                     /locus_tag="ROH59_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HDX4804304.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVP
                     GLDIGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPEEKPLGETLKDLFSR
                     PVLPEMTDVHLPLNLNIEEFKGEQLRVTGDTDITVRTMLLKVSSIDGNTKLDALDIDS
                     SQGIVNASGTAQLSDNWPVDITLNSTLNVEPLKGEKLKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQLYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGQEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEFPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVNI
                     NLVTLNAKGSEKQHELQLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVTDPQGRRNLGGNVNIRNFNLAMINPIF
                     NRGEKAAGMVSANLRLGGDVQSPQLFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEPKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            complement(32776..34509)
                     /gene="tamA"
                     /locus_tag="ROH59_001819"
     CDS             complement(32776..34509)
                     /gene="tamA"
                     /locus_tag="ROH59_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HDX4804305.1"
                     /translation="MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKARETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQTLDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGT
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            34715..35353
                     /gene="msrA"
                     /locus_tag="ROH59_001820"
     CDS             34715..35353
                     /gene="msrA"
                     /locus_tag="ROH59_001820"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDX4804306.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            35676..37019
                     /locus_tag="ROH59_001821"
     CDS             35676..37019
                     /locus_tag="ROH59_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDX4804307.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANM
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(37081..37287)
                     /locus_tag="ROH59_001822"
     CDS             complement(37081..37287)
                     /locus_tag="ROH59_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HDX4804308.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            37612..38169
                     /locus_tag="ROH59_001823"
     CDS             37612..38169
                     /locus_tag="ROH59_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDX4804309.1"
                     /translation="MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEKSSAVVVLDKDGRVQ
                     WAKDGALTQEEVQQVMDLLHKLINK"
     gene            complement(38159..38899)
                     /gene="cysQ"
                     /locus_tag="ROH59_001824"
     CDS             complement(38159..38899)
                     /gene="cysQ"
                     /locus_tag="ROH59_001824"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HDX4804310.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNVMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
     gene            39089..41032
                     /gene="cpdB"
                     /locus_tag="ROH59_001825"
     CDS             39089..41032
                     /gene="cpdB"
                     /locus_tag="ROH59_001825"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HDX4804311.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDIHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     LVVVLAHSGLSADPYKVMAENSVYYLSEIPGVDAIMFGHAHAVFPSKDFADIEGADIA
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARPIYDIANKKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPNSTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMINANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKG
                     QYPMNKVATDDIGFAIYQVDLSK"
     gene            complement(41161..41541)
                     /locus_tag="ROH59_001826"
     CDS             complement(41161..41541)
                     /locus_tag="ROH59_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDX4804312.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIAYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            41630..42490
                     /gene="qorB"
                     /locus_tag="ROH59_001827"
     CDS             41630..42490
                     /gene="qorB"
                     /locus_tag="ROH59_001827"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDX4804313.1"
                     /translation="MIAITGATGQLGHYVIESLMKTVPASQIVAIVRNPAKAQALAAQ
                     GITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKAAGVKFIAYT
                     SLLHADTSPLGLADEHIETDKMLADSGIVYTLLRNGWYTENYLASAPAALEHGVFIGA
                     AGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKSVT
                     YQNLSEADFAAALKSVGLPDGLADMLADSDVGASKGGLFDNSKTLSKLIGRPTTTLAE
                     SVSHLFNVNN"
     gene            42598..43563
                     /locus_tag="ROH59_001828"
     CDS             42598..43563
                     /locus_tag="ROH59_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709987.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX4804314.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLASVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNIQ
                     TPDFSLPFGPRPLVFISLMVAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLLRQQMPPLMTLSGIALLVIGVVIAVRAKPEKPLTESVSES"
     gene            43671..44333
                     /gene="ytfE"
                     /locus_tag="ROH59_001829"
     CDS             43671..44333
                     /gene="ytfE"
                     /locus_tag="ROH59_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HDX4804315.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALA
                     GE"
     gene            complement(44378..45790)
                     /gene="cycA"
                     /locus_tag="ROH59_001830"
                     /gene_synonym="dagA"
     CDS             complement(44378..45790)
                     /gene="cycA"
                     /locus_tag="ROH59_001830"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HDX4804316.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(46099..46719)
                     /gene="fklB"
                     /locus_tag="ROH59_001831"
     CDS             complement(46099..46719)
                     /gene="fklB"
                     /locus_tag="ROH59_001831"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDX4804317.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            46938..47576
                     /gene="ytfB"
                     /locus_tag="ROH59_001832"
     CDS             46938..47576
                     /gene="ytfB"
                     /locus_tag="ROH59_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YtfB"
                     /protein_id="HDX4804318.1"
                     /translation="MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIILVV
                     GFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQ
                     ESQPEEQPQTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
                     GAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR"
     gene            complement(47560..48207)
                     /locus_tag="ROH59_001833"
     CDS             complement(47560..48207)
                     /locus_tag="ROH59_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDX4804319.1"
                     /translation="MYLDTSNVQSLKEKLLLCAVNEFAEYGYEGARVDNIVKAAGCSK
                     QTVYHHFGNKENLFIEVLEYTWNDIRQKEKALDFSDLPPQKAIEKIIDFTWDYYISNP
                     WFLKIVHSENQSKGVHYAKSQRLLEINHAHLQLMESLLDEGKKQNIFKPDIDPLQVNI
                     NIAALGGYYLINQHTLGLVYHISMVSPQALEARRKVIKETILSWLLVDPSSTAHE"
     gene            48420..49211
                     /locus_tag="ROH59_001834"
     CDS             48420..49211
                     /locus_tag="ROH59_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="HDX4804320.1"
                     /translation="MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVE
                     KLHATQQECLAEGVEVICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRG
                     DLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
                     AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAK
                     GLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLSMPRF"
     gene            49221..50063
                     /locus_tag="ROH59_001835"
     CDS             49221..50063
                     /locus_tag="ROH59_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDX4804321.1"
                     /translation="MRDLLQRPDLFSINTATLGYKTPLPAIIDACAARGIGAIAPWRR
                     ELQSEDLQQTARQLAASNMNVSGLCRSTYYTAPTLAERKLAIDDNRRALDDAAVLNAA
                     CYMQVVGGLPMGTKDLYEAREQVKQGIRQLLPHSKEVGVPIALEPLHPMTAANRSCLC
                     TLRQALDWCDELDPDGEFGLGVAVDVYHVWWDPDLASQILRAGKRILAFHVSDWLVPT
                     TDLVNDRGMPGDGVINIPSIRRLVENAGFNGAIELEIFSPYWWQKDINSTLDISVDRI
                     AHYC"
     gene            50073..50849
                     /locus_tag="ROH59_001836"
     CDS             50073..50849
                     /locus_tag="ROH59_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDX4804322.1"
                     /translation="MNDQPVLFSRAAASCRLTLNREDKCHAINEEMIESLDHYLNEIE
                     NDTALRLVELTATGDKFFCAGGDIKSWSAYSPLDMGRKWIKRGNDVFNRLRNLPQLTV
                     ANLNGHTIGGGIELALCCDIRIARPGAKFSNPEVMLGMVPGWMGIERVLNQVGPVVGR
                     QMLMLGKRLTAQEAQTANLIDEVVEKEQVESWMANQLAQLEKCGPVALAHIKQLILAL
                     ENKHADYSHQLLAGLMSATQDCQQATHAFAEKAGVSFHNQ"
     gene            50859..52400
                     /locus_tag="ROH59_001837"
     CDS             50859..52400
                     /locus_tag="ROH59_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDX4804323.1"
                     /translation="MRKLSTAETLAAQIQDGATIAISGNGGGMVEADHILAAIEARFL
                     QTGHPRDLTLIHSLGIGDRDSKGTNRFAHAEMLKRIIAGHFTWSPKMQELVKNNAIEA
                     YCFPGGVIQALLREIGAGRPGLFTHVGLGSFVDPRNGGGKSNECTTDDLVELIEIDGE
                     TKLRYRPFKVDYAILRGTYADPRGNVSLEEEAIDMDSYSMALAAHNSGGKVFVQVRDV
                     LEAGTIEPRRVKLPGILVDGIVEHREQPQTYLGGYDLTISGQHRRLSSNDAIELVSHP
                     VRRLIARRAARELVAGASTNFGFGIPGGIPGVALREGVPYQSLWLSVEQGVHNGMMLD
                     DALFGCARNADAIIPSLDQFEFYSGGGIDITFLGMGEMDQYGNVNVSHLNGNLIGPGG
                     FLEIAQNARKVVFCGTFDAKGSKIDVTPDGLHIAQSGQIPKLVTQVEKITFSAAYAQQ
                     SGQEVLYITERAVFQLTAEGVELIEIAPGVEIERDILPYMAFRPIIRHPRLMESSLFM
                     PMEDA"
     gene            52397..54349
                     /locus_tag="ROH59_001838"
                     /pseudo
     CDS             52397..54349
                     /locus_tag="ROH59_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591423.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
     gene            54404..54676
                     /locus_tag="ROH59_001839"
                     /pseudo
     CDS             54404..54676
                     /locus_tag="ROH59_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT        13435 a        14433 c        13689 g        13135 t
ORIGIN      
        1 tatcgatctt ttcttcaaaa atcttaacga cataacccgg aagtttattt acaatttctt
       61 ttgttttttc ttcatcacca taaacatatc ctaactcatt aagatacatc tgttctccct
      121 cataactctt aagtaattga tagaagtacc acttagcaaa atcaggttgc ttcatgaaaa
      181 aatccttcaa aaaaaatatc attcactaaa atactgagag gcactttatc aaaaaccaat
      241 ttaacatcat caaatagcct tagtattaag cgcgattttt cttgattact taaattaaaa
      301 tcattgacat atacaaccaa cttctcccaa atcaattcct gtaactcagg gctgttttta
      361 tagggttctt tattgaggtt gaaaaataat gtctcagcta ttttagactg atcgcagtta
      421 aaatcaatat gatcgatcac ggagcgggca tgctttatct ttgtagtatc atcagaatat
      481 tgcatacttt gattaaaaca ccactccaga atttttacat cattaatata tggcaatttt
      541 aaaaaagtct tcaacatcga atcgatgacc ttttcgagat taacttttgc atcatctaag
      601 gaatcaataa gaatattaga caggttaatt ttgatgttat taatttcatc attaccttct
      661 gtaccactag caattctggt atcatgtaac gttttcagat catttatttc ttcaagtata
      721 ccaccttcgc ctagtaagta tggaatcgtg tcatcacata catgaggcat taatagcaga
      781 tgttctttct ttattttttc taatgtactg gctaatggct tttctaataa ctcgttataa
      841 tcaattgcgt ccttccagtt caactgatga ttatttaata gaagcgccat attcttgtta
      901 gcttcacgtt ggtaacacgc cagaaccttg ttagtaatca ggtgtaatga actatcatct
      961 tttctttcaa aagacttacc ttcataacga aaactcaaaa aatcagattg tggaaatata
     1021 atggctgtat gtccttgacg agtccccata gtagtggtag tagaaagtga aatttctata
     1081 atcaccttag atgaatccgc acgctcacct tcaggattat tcataacaaa attcattatt
     1141 tcactgccat cattattttt gatataagat gaggactcaa tatgagccat catatttcta
     1201 cccgcttcgt tggagcattt gctaaaatcc acataaccca gggtaaatat ttttgccaaa
     1261 aactccaaaa atgctccagg agatagaata ttccttctgc tatcctgccc ctcggcatta
     1321 cgagcaaaat cattcattcc cacacaccag gtatttaaga cttcattttt tggtttaaca
     1381 ttgtcggctg atgccatgtg ttgataacaa ttcaaatctg atatttttgc catgacgaac
     1441 tccttgagtt aataagaacg tctaagcatt acaaatttta ctcacaaaaa aatatcaaaa
     1501 atcgctcttt tcacaaactc gccgtaaacc tggagttatt tacggcgaaa agtcatcacg
     1561 ccatcagcat cttcactact gctttgcgaa cctgggctgg tgcacccact gcgcacagcg
     1621 gtttatgcac ttcccccgga taaaacacaa caaaatcacc ttcattcagg ataactgttt
     1681 tctcatcaac gacttccggc aaaaatgcga tgtctttatc tactaaccag tcggtctccg
     1741 gcgtacctgc aggttgtgtg ctgaaggtca tgccttcctg accttttaac acaatctgaa
     1801 tgtcgagata acgggcatgg tactccgcac ggcgagcttt gtacggctcg gtcatatctt
     1861 ccgagataag ataaaacaga cgattgcctt cgatatcgtg cttacccttt ggcgtttctg
     1921 ccgtaacgtg tgctttgata tgctcaatcg cctggcgtaa ctcctggggt agccatggct
     1981 gaagattatg aatatttccg atgatcatct tttccactcc ttaattaaaa caatgtttca
     2041 tttccaccgt tatacgaaaa gatgatcaat tccgccagcc ttaacgcgtg aattattgtc
     2101 ttatcacaac ttatcggcag gcgcgttccc gcctttcgga tcaaggtcag catcactcct
     2161 tgagaatagt ttttatcgct tcccccgcca gtgcagctgt tgcacagagt tgttcgaggg
     2221 agtgcccctc tcgtgccttc gcagaaagcc ctgacatcac ggtactcata aaatcagtca
     2281 cacattgtgc gctttgtgga tgccgcctgg cgatatagtc ataaatggtc gtttctgcgg
     2341 cgtgataata ttgaacggca atatcacgcg cttgtggatc atgactatga atgccttcaa
     2401 gaaccataca gccagcgcag ccgccgtttt ggctatatct gcgcgccgct tcttttaata
     2461 cctcagccag gcactcccct accggacgat catcacgaag aatatcggca agcggaatag
     2521 cttccgtacc gacatattca ttgagtacac ggctaaataa cccagcctta ctgccaaaag
     2581 ccgcgtagag actcgggggg ttaataccaa gataatcagt aacttcagca acactgacag
     2641 catcgaaacc tttttggtga aaaagcactt ttgccgcaga gactgcctgc tcaggagcga
     2701 aacgtctggg acgacctgga acgcgagatt gttttttagt gaccattaca aaacttgttg
     2761 acagaaagtt aaaacagttt tgtaatgcat gttacataat aaatcaagga gtccttatgg
     2821 gcgcttttac aggtaagaca gttctcatcc tcggtggtag ccgtggaata ggtgccgcta
     2881 tcgtacgtcg tttcgtcacc gatggagcca atgtacgatt cacctatgcg gggtcgaaag
     2941 atgccgctga acgcctggca catgagactg gagcgacagc agtattcaca gatagtgctg
     3001 acagagacgc tgttattgat gtcgttcgta agagcggcgc attggatatc ctggtggtaa
     3061 atgcaggtat tggcgtcttt ggcgatgccc tggaattaaa tgccgacgat attgatcgcc
     3121 ttttcaaaat caatattcat gccccttacc atgcctctgt tgaagccgcc cggcagatgc
     3181 ccgaaggcgg gcgcatctta atcatcggct ccgtgaatgg cgatcgtatg cctgttgcag
     3241 gcatggctgc ttatgccgcc agtaaatctg ccctgcaagg catggcgcgc gggctggccc
     3301 gtgattttgg accgcgtggg atcaccatca acgtcgtcca gccagggcca atagataccg
     3361 acgctaatcc cgccaacggg ccaatgcgcg atatgttgca tagttttatg gctatcaaaa
     3421 gacatgggca accggaagag gtcgctggaa tggtcgcatg gttagcaggg ccagaagcca
     3481 gttttgttac cggcgcgatg cataccattg atggcgcgtt tggggcataa ccgactacgc
     3541 tcaattaagc ccagccatta tccatgatgt ctgggttttg tttactcacg tcgttcccta
     3601 aaagcggctc ccggtaaata taaatcttct gttcatgtcg taaatcttga ggataaccaa
     3661 atggtagaaa gaaccgctgt tttccctgct ggccgacatt cactgtatgc tgaacatcgt
     3721 tattcggcgg ctattcgttc cggcgatttg ctgtttgttt ccgggcaagt aggaagtcga
     3781 gaggacggaa caccagaacc cgattttcag caacaagtca gactggcatt tgataatttg
     3841 catgcgaccc tggcagctgc gggatgcact tttgacgata tcattgatgt tacgagcttt
     3901 cataccgatc cggaaaaaca atttgaagac atcatgacgg tcaaaaatga aatatttagc
     3961 gcccctcctt atccaaactg gacggcggtg ggcgttacct ggctggcagg ctttgatttt
     4021 gaaattaaag tgatagcgcg catccctgag ctgtaagcaa tagtgttagc cgttcgtttt
     4081 cacactccgc cgtataagtc ggatgaatgg aataaaatgc atatctgatt gcgtgaaagt
     4141 gaaaaagaaa aaagcaggaa atgtctgcaa ttattgatac cgaacgacag ttctcttcca
     4201 gaatcaaagc aaataaaaat gcatacattt tgacttttaa ttcaaataaa ccgtttgcgc
     4261 tgacaaaata ttgcatcaaa tgcttgcacc gcttctggct atgagtataa tgccggacaa
     4321 tttgccggga ggatgtatgg ttcagtgtgt tcgacatttt gtcttaccgc gtctgaaaaa
     4381 agacgctggc ctgccgtttt tcttcccgtt gatcacccat tcccagcccc tcaatcgagg
     4441 ggcttttttt tgcccaggcg tcaggagata aaagatggct aatccgctat atcagaaaca
     4501 tatcatttcc ataaacgacc ttagtcgcga tgaccttaat ctggtgctgg cgacagcggc
     4561 gaaactgaaa gcaaacccgc aaccagagct gttgaagcac aaagtcattg ccagctgttt
     4621 cttcgaagcc tctacccgta cccgcctctc tttcgaaaca tctatgcacc gcctgggtgc
     4681 cagcgtggtg ggcttctccg acagcgccaa tacatcactg ggtaaaaagg gcgaaacgct
     4741 ggccgatacc atttcggtta tcagcactta cgtcgatgcg atagtgatgc gtcatccgca
     4801 ggaaggtgcg gcgcgcctgg ccaccgagtt ttccggcaat gtaccggtac tgaatgccgg
     4861 tgatggctcc aaccaacatc cgacgcaaac cttgctggac ttattcacta ttcaggaaac
     4921 ccaggggcgt ctggacaatc tccacgtcgc aatggttggt gacctgaaat atggccgcac
     4981 cgttcactcc ctgactcagg cgttagcgaa gttcgacggc aaccgttttt acttcatcgc
     5041 gccggacgcg ctggcaatgc cgcaatacat tctggatatg ctcgatgaaa aagggatcgc
     5101 atggagtctg cacagctcta ttgaagaagt gatggcggaa gtagacatcc tgtacatgac
     5161 ccgcgtgcaa aaagagcgtc tggacccgtc cgagtacgcc aacgtgaaag cgcagtttgt
     5221 tcttcgcgcc agcgatctcc acaacgccaa agccaatatg aaagtgctgc atccgctgcc
     5281 gcgtgttgat gagattgcca ccgatgtgga taaaacgcca cacgcctggt acttccagca
     5341 ggcaggcaac gggattttcg ctcgccaggc gttactggca ctggttctga atcgcgatct
     5401 ggtactgtaa ggggaaatag agatgacaca cgataataaa ttgcaggttg aagctattaa
     5461 acgcggcacg gtaattgacc atatccccgc ccagatcggt tttaagctgt tgagtctgtt
     5521 caagctgacc gaaacggatc agcgcatcac catcggtctg aacttgcctt ctggcgagat
     5581 gggccgcaaa gatctgatca aaatcgaaaa tacctttttg agtgaagatc aggtagatca
     5641 actggcattg tatgcgccgc aagccacggt taaccgtatc gacaactatg aagtggtggg
     5701 taaatcgcgc cccagtctgc cagagcgcat cgacaatgtg ctggtctgcc cgaacagcaa
     5761 ctgtatcagc catgccgaac cggtttcttc cagctttgcc gtgcgaaaac gcgccaatga
     5821 catcgcgctc aaatgcaaat actgtgaaaa agagttttcc cataatgtgg tgctggccaa
     5881 ttaattgcgg ttggtaataa aagtctggct ccctataatg agccagactt tttaccgctg
     5941 taataaagga gaaatcatga gcaaaactat cgcgacggaa aatgcaccgg cagctatcgg
     6001 tccttacgta cagggcgttg atctgggcaa tatgatcatc acctccggtc agatcccggt
     6061 aaatccgaaa acgggtgaag taccggcaga cgtcgctgca caggcacgtc agtcgctgga
     6121 taacgtaaaa gcgatcgtcg aagccgctgg cctgaaagtg ggcgacatcg ttaaaaccac
     6181 cgtgtttgtg aaagatctga acgacttcgc taccgttaat gctacctacg aagccttctt
     6241 caccgaacac aacgccacct tcccggcacg ttcttgcgtt gaagtcgccc gtctgccgaa
     6301 agacgtgaag attgagatcg aagcgatcgc tgttcgtcgc taatcttgat ggaaatccgg
     6361 gctatcatgc ccggattaag tctgatgaca aacgcaaaat cgcctgatgc gctacgctta
     6421 tcaggcctac gtgattcctg caatttattg aatttgttgg ccggataagg catttacgcc
     6481 gcatccggca tgaacaaagc ttactttgtc tgcaatctga atcggggcta tcgtgcccag
     6541 tttattcttt attgccagcc gtaacgacgg ctatagaacc ctttcaccaa ctgggttaat
     6601 gtcatatacc ctgccagaat cgcaaccagc cacgggaaat agcttaacgg cagcgcctgt
     6661 aattgcagat aactggccag cggtgaaaac ggcaatgcga tcccgacaat catcacgatc
     6721 acggtcatga tcattaacgg ccacgatgca cagctctgaa taaacggcac acggcgggtg
     6781 cggatcatat gcacaatcag cgtttgcgac agtaagccca ccacaaacca tcccgactgg
     6841 aacagcgttt gcgtttccgg cgtgttggca tggaataccc accacatcag gcaaaacgtc
     6901 agaatatcga agatcgagct gatcggtccg aagaagatca taaagcgccc cagatccgcc
     6961 gggttccaac gctgcggctt ttgaatttgc tcgtcgtcga cgttatcaaa cgggatcgcc
     7021 acctgtgaca catcatacag caggttctga ataagcaagt gtaacggcaa catcggcagg
     7081 aagggcaaga aagcactcgc caccagcacg ctgaacacat taccgaagtt ggagctcgcc
     7141 gtcattttga tgtatttcag catgttggcg aaagtgcgac gtccttcaat aaccccctct
     7201 tccagcacca tcaggctttt ttccagcagg atgatatcag ccgcttcacg ggcaatatct
     7261 accgcgccgt ccacagaaat gccgatatcc gcagcgcgta aggcgggcgc atcattaata
     7321 ccatcgccca taaagccaac cacatgccct tcgcgcttca gtaaggtcac aatgcgttct
     7381 ttatgcatcg gcgtcagacg agcaaacagc gtggtacgct gtgcgagatt tgccagttcg
     7441 tcgtcagata gcgtttcaat atcactacca atgaccacct ctcccgcgtc cagccccact
     7501 tcatggcaca ctttcgctgc aactaactca ctgtcgccag taaggatttt tacggtaatt
     7561 ccactcgctt ttaatgcctt cagtgccgga gcagttgtct ctttcggcgg atcaaggaaa
     7621 gcaatatatc cttcgaggat caggtcggat tcatccgccc gctggtaatc tccttcacgc
     7681 gctggcaggt atttcgtcgc caccgcaacc acgcgcagcc cctgacgatt cagcgtatca
     7741 gtaacccgct taatcttacg cagcatgatg tcatcgagcg gcacaatctc gccattgtga
     7801 cgcacctgcg aacacacatt gaggatttcc tgcaatgcac ctttgcaaac cagctgatgg
     7861 tgctcggtat tttctgccac taccaccgac atccggcgac gctcgaaatc aaacggaatc
     7921 tcatcgattt tttgccaacg actggccagc gagcgcgctg actcttcatc cgtaccttcg
     7981 agcaccgctg tatcgagcag gtttttaagt ccggtctgat aatgactgtt caaccacgcg
     8041 ctatgcagca cgcgttcgct ggttttaccg gagatatcgg tatgattctc cagcacaatt
     8101 ttgtcctgtg tcagggtgcc agttttatca gtgcacagaa tatccattgc gccaaagttc
     8161 tgaatagcat ccagatgttt gacgatcact ttctgtttcg acagctttac tgcgccgcgc
     8221 gccagcgtcg aggtaacaat catcggcaac atttccggcg ttaagcctac cgcgaccgaa
     8281 agcgcaaaca gtgccgcttc ccaccagtcg cctttggtgt aaccattgat taacagcacc
     8341 accggagcca tcaccagcat aaagcgaatc agcagcatac tgacgcggct gatcccttgc
     8401 tgaaaggcat tcggctcgct ttcctgctca ctaacacgcc ccgccagttg accaaaccag
     8461 gtattggcac ctgtagcaat caccattgct tgtgccgtgc cgctcaccac ggtggtgccc
     8521 ataaaacaca gggtgtcgca ctccagcgga ttgctgtgct ccggctggcg agtggtagct
     8581 gctttttcta cgggcagaga ctcaccggtt aacgacgcct gagcgacgaa cagatcccgc
     8641 gcctgcaaga tacgtaaatc tgccgggatc atatcccccg ccgccagttt tataatatcg
     8701 ccgggcacca gctggtcgat cgggatctcc agccagccat tttcgccttt gtcgttaatt
     8761 acgcgcagca ccgtcgcagt attgctgacc atcgctttca gggcatctgc cgctttagtg
     8821 gaacgtgctt cctgaataaa gttcagcaac gtagaaatag cgaccattag cgcgataacg
     8881 cccgcggcaa ataaatcttc cgtggcgtaa gaaatagcgc cgagaatggt gagtaaaata
     8941 ttaaatgggt tgcgatagca gacccataaa tgtacccacc acggcgacgg ttgttgtgcg
     9001 ggtaatttat tttcaccatg ttgttcgcgg gcagattcca cttccgcctg atttaaccct
     9061 tccggatggg tgtcgaacgt tttccataat tcttcttcgg gcatcaccgc cattttcagg
     9121 caatgcgcac ttaaggacgg cgggaccgcc gtattcactg tctgctgcgc gccaggcaat
     9181 ggatcgcgat gaaccagacg ggaaggtaaa tggcgaatga gccgggtaaa aatttcttta
     9241 aacataagga gtccctccgc actgtctgaa acagtacaga aatgtcttca ggcgtggcga
     9301 agccttacct gaaggtaata aagctgagca gggacgttaa aacgtcacgg ccttacgcat
     9361 ccggtaacgc cgtgaaaaga cgggcttacc ggaaaagttt taatctccgt cgagggagag
     9421 gcgtgggatc aggttccata taacctccgg taagtgaaaa aagcgccgca aataataagg
     9481 agaatccaat aatattcgta gcatctatgg cgatataata cctgctggca actaaaccaa
     9541 cgataaacca gactttaccc attgctgaat gcacgggtaa agttaggctc aaataattaa
     9601 acaacacgtt acaggacaac aggatgcaaa atcggctgac catcaaagac atcgcacgct
     9661 taagcggcgt ggggaaatct acagtttccc gggtgctgaa taacgaaagc ggcgtgagcc
     9721 agcgcacccg cgagcgtgtt gaagcagtga tgaatcagca tggattttcc ccttcccgct
     9781 ctgcgcgcgc tatgcgtggg caaagcgata aagtggtcgc catcattgtt acccgtctgg
     9841 attcgttgtc agaaaatctc gccgttcaaa ccatgctgcc agcgttctat gaacaaggtt
     9901 acgacccaat catgatggaa agtcagtttt ccccacaatt agttgccgaa catttggggg
     9961 tgctgaaacg gcgtaatatc gacggcgtag tgctgttcgg ttttactggc ataacagaag
    10021 aaatgttagc ccactggcag tcatcgctgg ttctgctggc gcgtgacgca aaaggctttg
    10081 cttcggtctg ttatgacgac gaaggggcaa tcaagatcct gatgcaacgg ctgtatgacc
    10141 aggggcatcg taatatcagt tatctcggcg tgccgcatag tgacgtgaca accggtaagc
    10201 gacgtcacga agcctacctg gcgttctgca aagcgcataa actgcatccc gttgccgctc
    10261 tgccagggct tgctatgaag caaggctatg agaacgtggc aaaagtgatt acgcctgaaa
    10321 ctactgcgtt actgtgcgca accgacacgc tggcacttgg cgcaagtaaa tacctgcaag
    10381 agcaacgcat cgacaccttg caactggcga gcgtcggtaa tacaccgtta atgaaattcc
    10441 tccatccgga gatcgtcacc gtagatcccg gttacgccga agctggacgc caggcggcct
    10501 gccaattgat cgcacaggta accgggcgca gcgaaccgca acaaatcatc atccccgcca
    10561 ccctgtcctg atcgtttcct gaacgataaa ttgtgatctt cgctgcgttt cgggaacgtt
    10621 cccgttttta aatttttccg cgcaatatat tctgcagcca accaaaaatg tcatctgcca
    10681 tggggcttta tgatgagcaa aataaaccaa acggatatcg atcggttgat tgaactggtc
    10741 ggcgggcgcg gcaatattgc gacggtgagc cactgtatta ctcgcctgcg ctttgtcctc
    10801 aaccaaccgg ccaatgccag accgaaagaa attgagcaac tccccatggt gaaaggctgt
    10861 ttcaccaatg ccgggcaatt tcaggtggtg attggcacca atgtgggtga ttactatcaa
    10921 gcactgattg cgtcaaccgg acaggcgcag gttgataaag agcaggtaaa aaaagccgcc
    10981 cggcagaata tgaaatggca tgagcagttg atctctcatt tcgcggagat cttcttcccg
    11041 ctgctgcccg cgttgattag cggcggtttg atcctcggtt ttcgcaatgt gatcggcgat
    11101 ttgcccatga gcaacggtca gacgctggcg caaatgtacc cttccctgca aacgatctac
    11161 gattttctgt ggttgatcgg tgaagcgatc ttcttctacc tgccggtcgg tatttgctgg
    11221 tcagcggtga aaaaaatggg cggcacgccg atccttggta tcgtgcttgg cgtgacactg
    11281 gtttctcccc agctgatgaa cgcttatctg ctcgggcagc agctgccgga agtgtgggac
    11341 tttggcatgt tcagcatcgc caaagtaggc tatcaggcgc aggtgatccc ggcactgtta
    11401 gccgggctgg cgctgggcgt tattgaaact cgccttaaac gcatcgtgcc ggattacctc
    11461 tatctggtgg tggtacccgt ctgttcgctg atcctcgcgg tgttcctcgc ccatgcgctg
    11521 attggtccgt ttggtcgcat gattggcgat ggcgttgcct ttgcggtacg tcacctgatg
    11581 accggcaact ttgctccgat tggtgcggca ttgtttggct tcctgtacgc gccgctggtg
    11641 atcaccggcg tacaccagac cacccttgct attgatttgc agatgattca aagcatgggt
    11701 ggcacgccag tgtggccgct gattgcgctg tcgaatatcg ctcagggctc cgccgtgata
    11761 ggcattatca tttccagccg caagcacaat gaacgcgaga tctccgtgcc tgccgctatc
    11821 tccgcctggc ttggggtcac tgagcctgca atgtacggca tcaacctgaa atatcgcttc
    11881 ccgatgctgt gcgcgatgat tggttctggt ctggcaggat tgctatgcgg cctgaacggc
    11941 gttatggcga atggcatcgg cgtaggcggc ctgccgggaa ttctctcgat tcaaccgagc
    12001 tactggcagg tatttgcgct ggcaatggct atcgccatca tcatcccgat tgtactcacc
    12061 tcgtttatct atcagcggaa ataccgcctg ggcacgctgg acattgttta attttcttcg
    12121 gggcgcaatt gcgccccctc gcatttgcag gaataacgta atgactaatc ttccccactg
    12181 gtggcaaaac ggcgttatct accagattta tccaaagagt tttcaggaca ccacgggtag
    12241 cggcaccggc gatttacgtg gcgttatcca acgcctggac tatctgcata aactgggcgt
    12301 tgatgccatc tggctaaccc ccttttatgt ctctccccag gtcgataacg gttacgatgt
    12361 agcgaactat acggcgattg atcccaccta cggcacgctg gacgattttg acgaactggt
    12421 gacgcaggca aaatcgcgcg ggattcgtat cattctcgat atggtgttta accatacctc
    12481 tacccaacat gcctggtttc gcgaggcgct gaacaaagaa agcccttacc gccagtttta
    12541 tatctggcgc gatggcgaac cagaaacgcc accgaacaac tggcgttcaa aatttggcgg
    12601 tagtgcgtgg cgctggcatg cggaaagcga acagtactat ttgcatctct ttgcaccaga
    12661 acaggcggat ctcaactggg agaatccagc ggtacgcgca gagctgaaaa aagtctgtga
    12721 attctgggcc gatcgtgggg tcgacgggtt gcgcctggat gtggtgaatc tgatctccaa
    12781 agacccgcgt ttccctgaag acctggatgg cgacgggcgt cgcttctaca ccgacgggcc
    12841 acgagcacac gagtttttgc acgagatgaa ccgcgatgtg tttacgccac gcgggttaat
    12901 gaccgtaggt gaaatgtcct ccaccagcct tgagcattgc cagcgatacg cggcactgac
    12961 aggcagtgaa ttgtcgatga cctttaattt tcatcacctg aaggtcgatt atcccggtgg
    13021 tgaaaaatgg acgctggcta aacctgactt tgtggcgttg aaaacattgt tccgccactg
    13081 gcaacaagga atgcacaacg tggcatggaa tgccttgttc tggtgtaacc acgatcagcc
    13141 gcgcattgtt tctcgctttg gtgatgaagg tgaataccgc gtgcctgcgg caaaaatgct
    13201 ggcgatggtg ctgcatggca tgcagggaac gccgtatatc taccagggcg aagagattgg
    13261 catgaccaac ccgcatttca cgcgcattac tgactatcgc gacgtggaga gcctcaatat
    13321 gtttgccgag ctgcgcaacg atggtcgtga tgccgacgag ttattggcaa tcctcgccag
    13381 taaatcccgt gacaacagcc gcacgcccat gcaatggagc aacggcgata atgccgggtt
    13441 tacggctggc gaaccgtgga ttggcctggg cgataactat caacaaatca acgtagaagc
    13501 cgcgctggcc gatgagtcct cggtgtttta cacctaccaa aagttaatcg cactgcgtaa
    13561 gcaagaagcc atcctgacat ggggcaatta ccaggatctg ctgccaaaca gccctgtatt
    13621 gtggtgctat cgccgtgaat ggaaggggca aaccttgctg gtcattgcca accttagccg
    13681 tgagatccaa ccctggcagc cagggcaaat gcgcggcaac tggcagcttg tgatgcataa
    13741 ctacgaagaa gcctcaccac aaccctgtgc catgaattta cggccttttg aggctgtctg
    13801 gtggttacag aagtaaatct tccctaagcc ccggtaatgc cggtcattcc ggggttttgt
    13861 ctgtcagcat gttgtttttg ttgatttttc aaccagcaaa ttcattaaaa aatttacata
    13921 acgctgtagc gcccgtcatc cgtacgctct gctttttact ttgagctaca tcaaaaaaag
    13981 ttaaaacatc cttgatgcaa agcactatat atagacttta aaatgcgtcc caacccaata
    14041 tgttgtatta atcgactata attgctacta cagctcccca cgaaaaaggt gcggcgttgt
    14101 ggataagcgg atggcgattg cggaaagcac cggaaaacga aacgaaaaaa ccggaaaacg
    14161 cctttcccaa tttctgtgga taacctgttc ttaaaaatat ggagcgatca tgacaccgca
    14221 tgtgatgaaa cgagacggct gcaaagtgcc gtttaaatca gagcgcatca aagaagcgat
    14281 tctgcgtgca gctaaagcag cggaagtcga tgatgccgat tattgcgcca ctgttgccgc
    14341 ggttgtcagc gagcagatgc agggccgcaa ccaggtggat atcaacgaga tccagaccgc
    14401 agttgaaaac cagctgatgt cgggtccata caaacaactg gctcgcgctt acatcgagta
    14461 ccgtcacgat cgcgacattg aacgtgaaaa acgcggtcgc ctgaaccagg agatccgtgg
    14521 tctggtcgag cagaccaacg cctcgttact caacgaaaac gccaacaaag acagcaaggt
    14581 gattccaacc cagcgcgacc tgctggccgg gatcgtggct aaacactatg cacgtcagca
    14641 cctgctgccg cgtgacgtgg tgcaggcaca tgagcgtggc gatattcact atcacgatct
    14701 cgattactca ccgtttttcc cgatgttcaa ctgcatgttg atcgacctga aaggcatgct
    14761 gacccagggc tttaaaatgg ggaacgccga gattgaaccg ccgaagtcga tctcaacggc
    14821 aaccgcggta actgcgcaga ttattgctca ggttgccagc catatttatg gcggcaccac
    14881 cattaaccgt atcgatgaag tgctggcacc gtttgtcacc gccagctaca acaaacatcg
    14941 caagaccgca gaagagtgga gcatcccgga cgccgaaggc tacgctaact ctcgtaccat
    15001 taaagagtgc tacgatgcct tccagtcgct ggagtacgaa gtaaacaccc tgcacaccgc
    15061 caacggtcag acgccgtttg taacctttgg ttttggtctg ggcaccagct gggagtcgcg
    15121 cctgattcag gaatctatcc tgcgtaaccg tatcgcaggc cttggtaaaa accgtaaaac
    15181 tgcggtgttc ccgaaactgg tgtttgcgat tcgcgatggc ctgaaccata aaaaaggcga
    15241 tccgaactac gacatcaaac agctggcgct ggagtgcgca agcaagcgca tgtatccgga
    15301 tatcctgaac tacgatcagg tagtgaaagt caccggttcg tttaaaaccc cgatgggctg
    15361 ccgcagcttc ctcggcgtgt gggaaaatga aaacggcgag cagatccacg atggtcgtaa
    15421 caacctcggc gtgatcagcc tgaacctgcc gcgtattgct ctggaagcaa aaggcgatga
    15481 agccaccttc tggaagctgc tggatgaacg tctggtgctg gcacgtaagg cactgatgac
    15541 ccgtatcgct cgtctcgaag gcgtgaaagc gcgcgtcgcc ccgatcctct atatggaagg
    15601 tgcttgtggc gtacgtctga atgctgacga tgatgtttct gaaatcttca aaaacggtcg
    15661 tgcgtctatt tcgctgggtt acatcggcat ccacgaaacc attaacgcgc tgttcggcgg
    15721 cgagcatgtt tacgacaacg agcagcttcg cgcgaaaggt atcgccattg ttgaacgtct
    15781 gcgccaggca gtggatcagt ggaaagaaga aacgggttat ggtttcagtc tctacagcac
    15841 gccgagtgaa aacctgtgcg accgcttctg ccgtctcgat actgctgagt ttggcgtggt
    15901 gccgggcgtg accgataaag gttactacac caacagtttc cacctcgatg tggagaagaa
    15961 ggtgaacccg tacgacaaga tcgactttga agcgccttac ccgccgctag cgaacggtgg
    16021 tttcatttgc tacggcgagt atccaaacat tcagcacaac ctgaaggcgc tggaagatgt
    16081 ctgggattac agctatcagc atgtaccgta ttacggcacc aatacaccga ttgatgagtg
    16141 ctacgagtgt ggctttaccg gtgagttcga gtgcaccagc aaaggcttca cttgcccgaa
    16201 atgtggtaac catgacgcct cccgtgtgtc ggtgactcgc cgcgtgtgcg gatatttagg
    16261 tagcccggat gcacgtccat ttaacgccgg taagcaggaa gaagttaagc gccgcgttaa
    16321 acatttgggg aatgggcaga taggttaatc ttcactctac gttaagcaaa tgccggatgc
    16381 ggcgtaaacg ccttatccgg cctacatggc aacaacgatt gtaggtctga taagacgcga
    16441 cagcgtcgca tcaggcgttg attaccggat gcatcctata cgcggactga taagccaggc
    16501 gaaacaatga attatcatca gtactatcct gtcgacatcg tcaacggccc cggcactcgc
    16561 tgcaccctgt ttgtctccgg gtgtgttcat gaatgccccg gttgctataa caaaagcaca
    16621 tggcgggtaa attccggtca gacatttact aaagcaatgg aagaccagat tattaacgat
    16681 ctgaatgaca ctcgtatcaa acgccagggt atttccctct ccggcggcga tccgctgcat
    16741 ccgcaaaacg tgccggatat tctgaaactg gtaaaacgca tccgcgccga gtgtccgggt
    16801 aaagacatct gggtgtggac aggctataaa ctcgacgaac tcaacgctgc gcaaatgcag
    16861 gttgttgatt tgattaacgt actggtcgac ggcaaatttg tgcaggattt aaaagaccct
    16921 tccctgatct ggcgcggcag cagcaatcag gtggtgcatc atttgcgatg ataagttccc
    16981 tgttacctga gtgcaggcaa cagggaaatg aggaattaac gatacttctg gtgataggcg
    17041 ttgcgggtcg ttttcagttg ctctgcagca gcctgcgctt cttttacttt accttcattt
    17101 gccagcttca gcgcgtcgtc aatctgaccg accagaatgt cgaaaccgtg gcggaaatct
    17161 ttcatttccg ggctgtccgg tgatttatct tcgagcttcg gcggcgttgc tttttgcgca
    17221 tccagcgctg cggcgcgcat cttcgttaac gcgtctttga cttgcgccgc gttatccgct
    17281 ttttcgatca cttttaaatt gtcgttgagg gtttccatat tgtcttcaag atcagcggca
    17341 aacgacgcag aactgaatac caacgaggag actgcaagaa tagctaacag gcttttacgc
    17401 attgctcact tcctttttta tttacacttc atccttcaca ctgcctcatc gacggctacg
    17461 ctcattcgcc cgggtcacgt actgcgagta cgctccccgg ccctcattca ctttccgtct
    17521 cgatgcagtg cgaatgattt tgtgtaattt tttagtttat agcgcggcag gtcgcgccag
    17581 ttttttactg cccggcgatt ttcatctccg gcaacagcac agaaccacac tgtatattac
    17641 tgcgtgtttc aatatcgtta ccgacggtga caatattgcg ccacatatct tttaaattac
    17701 ctgcgatggt gatttcacta acgggatact gaatttcgcc attctctacc cagaagcccg
    17761 ctgcaccacg ggaataatca ccggtaatgg cactcacgcc ctggcccatc agctccgtca
    17821 ccaccagccc ggtgcccatc tctttgagca tttgttcgaa gcttagccct tgtccggcaa
    17881 tccgccagtt gtgaataccg cccgcatgtc cggtgctttt cagccccagt ttccgcgccg
    17941 agtagctggt cagcagccac tgagtcagga tgccatcttt aataatatcg cgacgctcgg
    18001 tgcgcacacc ttcgctgtcg aatggcgtcg acgccagccc tttcagcaga tgcggatgct
    18061 cttcaatggt cagccagtcc ggcagaattt gtttacccag cgaatccagc agaaaggtag
    18121 atttacggta aaccgagcca cccgctatcg cccccaccag atggccaaaa agcccggttg
    18181 ccacttcatt ggcaaaaatg actggcgctt tcatggtgga gagtttacgc ggtgacaggc
    18241 gcgataaagt acggcgagca cagtcggccc cgacccactc tggcgtttgc agatcgctca
    18301 tcgcgcggcc aatggtgtag gcgtaatcac gctccatatc gccattttct tcggcaatta
    18361 cacagctgga gagtgaatga cgcgtagagc agtaaccctg caacatgccg tggctgttgc
    18421 caaaaacttt gacaccgtag tggctgttaa aactgccgcc ttcggtattg gtaatgcgtt
    18481 tgtccgcctg caatgccgcc tgttctgcgc gggccgccag ttcaatggct tcatccgggg
    18541 aaacttccgc agggtggaac aagtcgagat ctggtgcgtc aaaggccagc agctctttgt
    18601 ctgccacgcc ggcacaggga tctggcgagg tataacgggc aatatccagc gccgcctgta
    18661 cggtgcgggc aatggcctgc gggcttaaat cggtggatga tgcgctacct ttgcggttct
    18721 ggtgataaac agtgatcccc agcgcgccat cgctattgaa ttcaacattc tccacttcac
    18781 cataacgcgt gcttacgcta atgccggtgg tcttgctgac ggcaacttcc gcaccgtccg
    18841 atttgcctga ggccaactcc agcgcagtgg aaactgcttc ttccagaatc ttgcgctgcg
    18901 cttcaacttg agagattact ttcattgcaa gtgccataat gtagagagtt tctctgaagt
    18961 ctaacagaga accgtttttc agtgcgcatc ttaactggta acattagcct ctttttttaa
    19021 ggagcctgag atgactaagc agcccgaaga ctggctcgac gacgttcccg gtgatgacat
    19081 cgaagacgaa gacgatgaaa ttatctgggt cagtaaaagt gaaattaaac gtgatgccga
    19141 ggagctaaaa cgccttggcg cggaaattgt tgatctgggg aaaaacgcgc tggataagat
    19201 cccgttagat gcggatctgc gcgcggctat tgagctcgcc cagcgtatta agatggaagg
    19261 tcgccgccgc cagttgcagc tcatcggtaa gatgctgcgc cagcgcgacg tagagcctat
    19321 tcgtcaggcg ctggataagc tgaaaaaccg tcacaaccag caggtggtgc tgttccataa
    19381 actggaaaac ctgcgcgatc gtctgatcga tcaaggtgat gacgccatcg ctgaagtatt
    19441 gaatctgtgg cccgatgccg atcgtcagca gctgcgtact ctgatccgta acgcgaagaa
    19501 agagaaagaa gggaataagc cgccgaaatc cgcacgccag attttccagt atctgcgcga
    19561 actggcggag aatgaagggt aattttcgtt gttgatgtga gtatggtttg ccggatgcgg
    19621 tgcacctgta ggccggataa gacgcatcaa gcgtcgcatc aggcactatg ctcaaatgcc
    19681 ggatgcggcg taaacgcctt atccggcaat gctatctcag gctgaggccg aattactgcg
    19741 cagcttccgc cttcttcgcc agaccatcca gcagtttctg atggatccca ccaaaaccgc
    19801 cgttgctcat gaccagaata tggtcgccag gctgagcggt tttcaccacc atatctgcca
    19861 gcgtatccac atcgccactc cagtgtgcag gctgaacgca ggcttctgcc acttctgcca
    19921 cctgccacgg aatatgcgcc ggttgcagca ggaagacttc atcggcacga cctaatgaag
    19981 gtgccagatc gtctttgcag atccccattt tcatggtatt cgagcgcggc tccagcacag
    20041 caataatgcg cgccgtacca ccaactttgc cacgcagcgc cgcaagcgtt gccagaattg
    20101 ccgtcgggtg atgggcaaaa tcgtcatata ccgtcacgcc attcgcttca ccacgcaact
    20161 ccagacggcg acgagcgtta ataaacgaac ccagcgcgtt agcggcatct gcaggcgcta
    20221 caccaacatg gcgagccgcc gcaatcgcca tcaggccatt gtgcatatta tgttcgccca
    20281 ccagcgacca tttcacttcg cccacttttt cgccatccag caagacttcc cattcagaag
    20341 cgtcagtggt cagctttttc gcctgccagt gaccctgctc acccaccagc tcctgctcgc
    20401 tccagcagcc catcgccatg gtctgtttca ggttgatgtc attttccggc cagataatac
    20461 ggccctgccc cggaacgata cgcaccagat ggtggaactg tttctggatc gctttcaggt
    20521 cgtcaaagat atcggcgtga tcgaactcaa ggttgttgag gatcagcgta cgcgggcagt
    20581 aatggacaaa tttagagcgt ttgtcgaaga aggcgcagtc atactcatcc gcttcgataa
    20641 caaagaagtc gctttcgccc agacgcgccg aaacctcaaa gttccccggc acaccgccga
    20701 tcacaaatcc cggtttgtaa ccgcactgtt ccagaatcca ggtcgccatt cccgcggtgg
    20761 tagttttgcc gtgtgtaccg gcaacggcca gcacccagcg gtcgcgcagc acaaaatcgt
    20821 gcagccactg tggacctgac atataaggga tgtttttttc cagtaccgct tccacacacg
    20881 gatttccacg ggtcatggcg ttgccaataa tcaccagatc cggctgcgga tcgagctggc
    20941 tggcatcgta accctgaatc agctcaatgc cttgcttctc aagtaaggtg ctcatcggcg
    21001 gatacacatt ggcgtccgaa cccgttactt catggcctaa ctggcgcgcc agcatcgcca
    21061 gaccgcccat aaatgtgcca caaattccta aaatatgaat gcgcatacgt cactatcctt
    21121 ttttaatctg ccgctcattt tacgcatatg tcgggcaagt gagaaacgca tttcaggata
    21181 atccgcaatt tgctggcgcg attcacctga gcgcaacatt gagattattt gttaagattg
    21241 ttgcggtcgc tttactccat aaacattgca gggaaagttt tatgaaaacg ttaggtgaat
    21301 ttattgtcga aaagcagcac gagttttctc atgctaccgg tgagctcact gctttgctgt
    21361 cggcaataaa actgggcgcc aagattatcc atcgcgatat caacaaagca ggactggttg
    21421 atatcctggg tgccagcggt gctgagaacg tgcagggcga ggttcagcag aaactcgact
    21481 tgttcgctaa tgaaaaactg aaagccgcac tgaaagcacg cgatatcgtt gcgggcattg
    21541 cctctgaaga agaagatgag attgtcgtct ttgaaggctg tgaacacgca aaatacgtgg
    21601 tgctgatgga ccccctggat ggctcgtcca acatcgatgt taacgtctct gtcggtacca
    21661 ttttctccat ctaccgccgc gttacgcctg ttggcacgcc ggtaacggaa gaagatttcc
    21721 tccagcctgg taacaaacag gttgcggcag gttacgtggt atacggctcc tctaccatgc
    21781 tggtttacac caccggatgc ggtgttcacg cctttactta cgatccttcg ctgggcgttt
    21841 tctgcctgtg ccaggaacgg atgcgcttcc cggagaaagg caaaacctac tccatcaacg
    21901 aaggaaacta cattaagttt ccgaacgggg tgaagaagta cattaaattc tgccaggaag
    21961 aagataaatc caccaaccgc ccgtatacct cacgttatat cggttcactg gtcgcggatt
    22021 tccaccgtaa cctgctgaaa ggcggtattt atctctaccc aagcaccgcc agccacccgg
    22081 acggcaaact gcgtttgctg tatgagtgca acccgatggc attcctggcg gaacaagcgg
    22141 gcggtaaagc gagcgatggc aaagagcgta ttctggatat catcccggaa actctgcacc
    22201 agcgccgttc gttctttgtc ggcaacgacc atatggttga agatgtcgaa cgctttatcc
    22261 gtgaattccc ggacgcgtaa tctcctgcgc ctctccacac ggagaggcgt ttttatcgct
    22321 gcgcaatatt gactcttgtc actggcgaac tctgacgatt ctcccacagc accgttaatc
    22381 cacgctgtaa ggcaataaaa atgaacagca aaatgccgat ggcgattttc gtccaccagg
    22441 aactcagcgt accgtcaaag ttgatataag tctgaattag cccctgaatc gccacgccaa
    22501 aaagcgtccc taataccgtt ccaacgccac cgctcaaaag cgtaccgcca attaccactg
    22561 aggcgatagc atccagttcc acacctacgc ccgccagcgc atatccggcc tgggtataaa
    22621 tcgagaagac aatccccgcc agcgttgcca gtccggtgga gagcatataa atgcgaatag
    22681 tggtgctgcg ggtagaaatc cccatcaggt ttgccgacgt tgcgttgccg ccaatggcgt
    22741 atacctgatt accaaaacgg gtacgatgcg cgaggaatat gccgataacc accaccgcca
    22801 gcatcagcag tcccatcgca cttaagcgac cgccgccagg gattttccac gcaaggcttg
    22861 agagcgtgtc ataaatggga tggtttatcg ggatcgactc ttctgaaacg agatagctga
    22921 cgccgcgcaa aaagaacatt cctgccaggg taatgataaa tgccgggatc ttcagggcgt
    22981 cgatcaaaag ccccataaat gcgccaaagg cacagcccat caccagcact agcggaaacg
    23041 ccagcagcgg cgagaggccg aaatcgccaa tcacttttgc cagaaacacg ccagtaaagg
    23101 cgatcaccga accgacggag agatcgatac cgccagagag gatcacaaag gtcatgccaa
    23161 cggcgattat cccaagaaag gcgttatcgg tcaggatatt gcagatcact cttgtggaag
    23221 caaaaccggg aaactgggtc aggcagtaga gatagcccag cacaaagacg ccgatggtga
    23281 tcatcagcgg caagttacgt tttatcatgg ctacgtactc ctttaatcag actgataaag
    23341 cgttgcgact gaacaatcag cacacaaagc accaccaccg cttttacgac ctggttcatc
    23401 tccggcggaa agccagaaag taaaattccg gtgttcatcc cctgaataat cagcgccccc
    23461 acgactgaga gcagcaggtt aaagcgcccg cccatcagcg atccgccgcc aatcaccacc
    23521 gcaagaatgg cgtccagctc cagccataac ccggcgttat tggcatcggc accgcgaata
    23581 tccgccgcca cgataatgcc cgcaatcgcc gcacacagcc cgctcaacac gtaggtgagc
    23641 atgacgatga tccgcgtgtt taccccggca ttttttgccg cccgaatgtt gataccaacg
    23701 gcttcgataa acatccccag cgccgttttg cgggtcaaca gccagaacag gagaagcgtc
    23761 agcaccgcga taatgaccgg cgttggcagg aacaacagcg atccgctgcc aaaccatgag
    23821 agatccggcg agttaaacgt gacgatctgc ccggcggtga tcagttgcgc cacgccgcgc
    23881 ccggcgacca tcaggatcag ggtggcgaca aacggctgaa ttttgaggat cgctaccagt
    23941 atgccgttcc acaatcccgc caggatgccg gtgcccaggg cgcttaacaa aacaatcggc
    24001 aggctgaatc ccgcgaccgt catcgcagcc gttgtggctc cggcgatagc catcaccgcc
    24061 cctacggaga gatcaatccc accggtggcg atcaccagcg tcataccaat cgccagtaac
    24121 gcaacgggag ctgcacggtt aagaatgtcg atagggctac cgaacaaacg cccatcctga
    24181 agcaccacct gccagaaatg cggggctacc aggctatcga ccagcagcac cagcaatagc
    24241 gccgccagct gcggcattcc cgttggccag cgaaagcgcc ttttcggcgg cgtagtgtcc
    24301 gggagagatt gaggcatcac actgttctcc ttacgccgca atggcgttca tgatcgccgg
    24361 aacggaaagc tctgccagcg ggatctccgc cacctgtttg cgatcgcgca tgataatcac
    24421 ccgatcggca tagcccacca gctcttccag ttcggaggag atcaccaaca gcgccagacc
    24481 gtcagcacac agcgtttcaa tcaggcggat gatctcggcg tgggcaccaa catcaatgcc
    24541 gcgggttggc tcgtcgagga tcagaaattg cggtcgggtc agtagccaac gtgaaagcaa
    24601 cactttttgc tgattgccgc cagagagaaa ttcaatcggt tgttcagttg aaggtgtgcg
    24661 aatgccaagc tggcggataa agcgttcggc aatctcttgc tgctctttgc gggaaatggg
    24721 tcgtagccag ccgcgctggg cctggagagc gaggatgata ttttcccgca ccgaggcggc
    24781 agcgatgatg ccatcggttt tcctgtcttc cgggcagaat ccgatgccca gtactgaagc
    24841 ctgatgtggc gatcgcaggg tttgcggttt gcctttgatc aacgccgtgc cgctgtcagc
    24901 aggtttgata ccgaagatca cttcggcggt ttcggtacgt ccggatccca gcaagccagc
    24961 cagaccgacg atctcgccgg ggcgcacttc gagatcaaac ggtgctatcg ttcctttttt
    25021 gccgtaattt ttgaacgcgg caacgggttt gtcgctcaac aatgttcgcc cggcacgctg
    25081 tagcgcgtgg gtatccagct cgcgccccag catcattttt accagttcga tctgcggtag
    25141 ctcgcgcgtt tcccgacagc ctacgaaact gccgttgcgt aagacggtga tccgatcgct
    25201 gacctgatag acctgatcga gaaagtgagt gacaaagatc aggctgacgc cgcgatcgcg
    25261 caactgacgc atcaggccaa ataatagctc cacttcctgg gtgtcgaggc tggcggtggg
    25321 ttcatcgagg atcagcactt tggcggagag atcgatagcc cggcaaatgg cgacgatttg
    25381 ctgcatcgcc accgaaaaac ggttaagcgg ttcgcgcacg tcgagggaga aaccgtaaga
    25441 tgccatcagt tcggtggcgc gcttttccat ctctttacgg cgtagaaggc cgaaacgttt
    25501 gggttcgcgg cctataaata gattatcagc aaccgacata ttgggtagca ggttgacttc
    25561 ctgatagacg gtgccgatac cgagttgttg tgcatgggcg gtatttttcg gtgagatagc
    25621 ctggccttcc agccagatgg tgccgcgatc ggcgtggtat acaccagtta atgctttgat
    25681 tagcgttgat tttcccgccc cgttttcacc aagcagcgcc atgatttcgc cacggcgcag
    25741 gctgaaatca acgttgtcta acgctttgac gccggggaaa aatttactta atccttcggt
    25801 gcggaggatc tcctggtgtt ggtcggtcgt catggtttcc cccggtgtaa agcgtgctcc
    25861 cagtaggcat gataagacgc ggtaagcgtc gcatcaggct tcagtgcacc atcgccggat
    25921 gcggcgcgag cgccttatcc ggcctacgaa tcggcatcag gcatagcaac cctcaatacc
    25981 ccatattttt cttcttctct aactcttctt ttgcggtatc aggcagataa agggtggatt
    26041 tggtcagcgt cagcttttca ggcatggtgc cgtctttttt gtatttctcc agcgcgtcga
    26101 aggcgggacc tgccatattc ggcgtcagtt caacactggc gttcgcttcg ccatcaatca
    26161 tcgctttgta gatatcgggt acaccgtcaa tggaacccgt gaggatatct ttgcccggtt
    26221 tcaggcccgc ttctttaatt gcctgaattg cgccaatcac catgtcatcg ttatgggcgt
    26281 aaaccatgca gatgtttttg ccgttgtttt ccgctttgat aaagctctcc ataacttctt
    26341 tgcctttact gcgggtgaag tcacctgact gcgagcggat gattttgata tttggcgcat
    26401 tcttaatggc ttcggcaaag cctttcttac ggtcaatggc gacgctggcc ccaacggtgc
    26461 cctgcagttc caccacgttg catggtttgc cattcacttc ttttaccagc cagtcaccaa
    26521 tcaacttgcc ttcgaggatg ttgtcggcag tgacggtggt catatagaga gatttgtctt
    26581 tcacatcgat ggaacggtca agcaagaaga ccgggatttc ggcatctttc gcctctttta
    26641 ataccggttc ccaacccgtc gcaaccactg gagcgataaa gatcgcatcc accccttgtg
    26701 caacgaagga acgtaccgct ttaatctggt tttcctgctt ttgctgacca tcggcaattt
    26761 tcaacgtaat tccgcgtttt tcggcctcac ttttcgccac attggtttct gcagcgcgcc
    26821 agccggattc cgatccgacc tgcgaaaatc ctacggttaa tggagcggcc aacgccatag
    26881 acgacatggc tgccgagact gcagagacta caagtaagcg tttccacata gggttgtcct
    26941 cgtcggggta attattattg gtgaaaagat gttcgcgaaa aaactataga caattcgtta
    27001 tgtaacggat tgcgttacat cacacttcaa aaaagtaaat aaaacgttaa tcacaagttt
    27061 gtaatcgctt tcatctcact atgaaaaatg cggctacggt tatggatttt cctgctctgt
    27121 ataccgtctt aaaactggcg aaaaaggaaa atgaagacga aaacaagcaa agacattcgg
    27181 cgcgagttgg ctataatact cggcacttgt ttgccacata tttttaaagg aaacagacat
    27241 gagcttactc aacgtccctg cgggtaaaga tctgccggaa gacatctacg tggttattga
    27301 gatcccggct aacgcagatc cgatcaaata cgaaatcgac aaagagagcg gcgcactgtt
    27361 cgttgaccgc ttcatgtcca ccgcgatgtt ctatccgtgc aactacggtt acatcaacca
    27421 caccctgtct ctggacggtg acccggttga cgtactggtc ccgactccgt acccgctgca
    27481 gccgggttct gtgatccgtt gccgtccggt tggcgttctg aaaatgaccg acgaagccgg
    27541 tgaagatgcg aaactggttg cggttccgca cagcaagctg agcaaagaat acgatcacat
    27601 taaagacgtt aacgatctgc cagagctgct gaaagcgcag atcgctcact tcttcgagca
    27661 ctacaaagac ctcgaaaaag gcaagtgggt gaaagttgaa ggttgggaaa acgcagaagc
    27721 cgctaaagct gaaatcgttg cttccttcga gcgcgcaaag aataaataag ttcttctagc
    27781 gcaataaccc tgaacgccga gcttcggtta gtaagggttt ttttatgccc gcgataaata
    27841 aacacacctt attccaccac cgcctgcaag cgtaataacg cctcttccac cacctcatcc
    27901 gcagccagac caatacgctt tgccagccgg gcgcgtagat ccatcatccg cacctgattc
    27961 accagcacca cgccgtgcac atcgccttct tcgcaatgta aaggaacgct aaatccggca
    28021 taacgggcaa aatttccgcc ctgcgtaatg ggggccacca gcgtcattcc cagttgatta
    28081 aaggcttgaa cggagagcac aagcgcaggt cgaccagcac cttgctgttc atggccgctt
    28141 gctggatcaa agccaaccag cacaatgtct ccccgttcaa attcactttt ctttaccata
    28201 tttcgtcacc cgcaggggtg gatttacccc agacatcctg ctcgctaagt tccgcggcgt
    28261 tcatgtcaca ctgtgccagc agttcatcaa gcgagtagcg cctggagatg ggtgtcagaa
    28321 tcagttgatt gttgctcact tgcgcctcca cgctctgccc cggctgtaag ttaagttctt
    28381 tcattacgat attgggaatg accatacctg cactgttccc ccatcttttt atggtaatac
    28441 gcatctgcac ctccttaagt tatacaaagt ataactcacg gtgctacagg aaacgtttta
    28501 cccctgcgca tttgtgaacg ccagcagagt tttttatgcg ttaacagata tggaaagcgg
    28561 ctcggagaga aaagcaaagg gtgagggaat tacaaaacag aatgcgagtc gtctcgcaaa
    28621 aaacaacgcc acccgaaggt ggcgtatgca tatggttact tatccctgtc taaccagtcg
    28681 ccgctttcaa ttagctttaa tccatcgacg ggtcgttgat aaacgtacat ccatgcactc
    28741 ccgtacggcg tctgaatcaa ctggcgcgcg tattcaccgc ccctggtgcg caaggcatca
    28801 agttcggcca gcgtggcgtt gtcaatacga taaacttcac cgtgtactgt tccgttcccc
    28861 ggaactgcgc ctggatagtg gcccaggcta tacaactggt agttatcgat actgaaatcg
    28921 cccagtaact gggcattggt catccagtga ctgttgcctt gtttgtggcg taaactgccg
    28981 tagacaaata ttcgcattgc taaaactcga actgatagag caaatccagt gcctggtcta
    29041 caccagacac ggcttccaga tatagcttag gcatcaggcg ataacgtaac gtgagtgttg
    29101 ctatagagtc aaatataccc acgccgtatt tcacttgcag acctggcaat acatagccgc
    29161 tgactactac ctgggaggag tcgcctactc cctgggtgtc gagcgctaaa ttgcttacgc
    29221 caaacgtctc gccgatttta cccacaatct ggccactttg cgcaaccccc agaccaatca
    29281 gcatcgaggt cattgccgca ctgtcgctct gatcgctctc cagcccttgt ccacgtagca
    29341 aataagacaa tgcagcttgt tgcgacatcg ccgggtcaga gaagatctcc gctttcggtt
    29401 cgtccgccag accagtgacg cgaactccgg cgattacgtc gtcttctgta gcatccgggt
    29461 tacgaatagc ttcaatatta agatacggtt gatccggcgg accagagaac agtaactcac
    29521 ccttacgcac aatcagatcc tgaccatagg catggaagcg cccttcaggg atgttgatct
    29581 gcccgttcag gcccagccct tgtttgtcct gaacgacgtt aagatcgccc gtcagccgcg
    29641 ctttcaggcc aaaggcgtca atgcgcacat tgttgccaac gtggacaatc aggttactgt
    29701 taatcggaat cgacgccgtt ttcggctctt ccggttgcag gttatcgtta agcatcacca
    29761 catcgctgga gacgcctact gcgctttccg gcagatcgtg caccacgatg cgcgcccacg
    29821 ggacatccac gcgaccatcg agggtaaaca ggtttggtgt agcctcgaat acaacatctg
    29881 gcgatacatc cattcgtacc atcggcggca cggtgatccg cactttactg cctttcgccg
    29941 ttactcgtgc ccgccagttt tcaatttggc tccagtcggc atcaccgttc aggtagattt
    30001 caccctgctg ggtccgtact gtaccggcaa gcgtcgagcg cataccgtta aagttgaccg
    30061 caagctggct cggctgcata tcaaacggca taaagttgcc gtcgatatcc acacccgtaa
    30121 cctgaagctg accaaacaac tgcgggcttt gcacatcacc acccagacgc aagttggcac
    30181 tcaccatccc cgctgctttt tccccacggt taaagatggg gtttatcatc gcaaggttga
    30241 agttacggat attgacgttg ccaccaagat tacggcggcc ttgcggatcg gtcacctgca
    30301 cctgtccatc aaactggccg ttattggtca ggcggatggt ccagcccaat tcggcacggt
    30361 tgttacgcaa ttccgccgtc agattcagtg tctgaaacgc cacgggcagc gccgcatcgt
    30421 tgacggtttg cgttacctgc acgttacgcc ccgaaagggt gatactgccc tgcggcagcc
    30481 cctctttcgt ggtgtcccag gcaacatccg ctttacccgt gaagataccg ctggcctgag
    30541 tggtttctgg cataaacggt ttcagcatgg cgaggtcgaa gcggttgaga ttcaccaccg
    30601 cacgcccttc ggcccccgca tcgatagttt gcggcacgca cagttccgca ttcgggttaa
    30661 gccagcagtg tggcccgatg ctgatttttt gctccttatt gcggtaatcc agcgcaatat
    30721 cgcgggtcag cgaccacggg ccgaccggcg tctggaagcg ggtattgcta agagttccct
    30781 tccagcgttc ttctttgcga tcaaaacttc ctgccagatt aagctgcccg gagacaggct
    30841 cgccctgaat ccgcaactgt agctcgtgct gcttttcgct gcctttggca ttcagggtga
    30901 cgaggttgat atttacatcc ggctgcgaaa tttgctcaac gcgtacgtcg agtttcccgg
    30961 cgatctgatc ggtggattta atgtcgcctt ccacgcgaac ctgcgccacg gaaagttcct
    31021 gccagcgcag gccgcgcgcg gtgatatctg ccagtagttg tggcgcttcc accgtgccgc
    31081 gtactttcac cagccctttc gctgtaccgc caagccccgg cagcgcgtta tccagccccg
    31141 gcgcgttgat ggtggcatca agattgagat cttttacccc cagctcgcct ttcacttcgg
    31201 cactgtttgg cccgagttcc agatgcagcc ctgggatcat ccactgcata taactgttgc
    31261 ctttcagcgt gccgtcaacg ttcactttgt tctgtttgac gttaccggtc agcttcagtt
    31321 ctggcacctc catctgccag gtgccgccgt acaggctacc gcgggtttta atcaagccat
    31381 tgagtttcga cggccactcc gggaactctt tggcggtgtt aatgccatta agcgttagct
    31441 caccgcgcca actaatggcc tgctgccagt cgagcaacgc cttgagttca gttttccctt
    31501 ccagcgccgc gacggtgagt ttgtcgagat tgacctgctg ttcattacct ttggcatcaa
    31561 gggtaatggt ggctggcggg atctcctgtc ccttcactgc cgtacgcata gagagcgtgt
    31621 aatcggtcat tttgccggta agtttcagtt tcagatcatc cgcctgatac tgcttctcac
    31681 cagtgaacgg ccagtaaagc tgtttgctgt tcacttccac gttgagcggc aatccggctt
    31741 ccgccagtcg cgtctgggcg cgtaaatcca tatccaccgg accggaaagg ttaacgccaa
    31801 tctccagctg ttcgcgcagc gcaccgccca ctttcagctt cagtttttct cctttcaacg
    31861 gctccacgtt cagtgtgctg ttgagggtga tatccaccgg ccagttgtct gacagctgcg
    31921 ccgtgccgct ggcgttgacg atcccttgac tggaatcgat atccagggcg tccagtttag
    31981 tattgccgtc aatgctgctc actttcagca gcatggtgcg cacggtgatg tccgtgtcgc
    32041 ccgtcacgcg taactgctcg cctttaaact cttcaatgtt caggttaagc ggcaaatgca
    32101 cgtcggtcat ttccggcaat accgggcgag aaaagagatc tttcagcgtt tcgccgagcg
    32161 gcttttcctc cggctgcgga ttttcaattt tcggttcgac cacttcttcc tgcgccactt
    32221 ccgccacttt cggcagagca atcagcaggc ctttcagcga cgtcggtttc agggtcaggg
    32281 ttttctcctg ccagttcagg ccggaggtga agtccatcac cgacaccgtg gtgtcatcaa
    32341 tcttgatgtt gacgttgtcc agcgccaccc gtgtcagggt gatgggatac ggcgtggaga
    32401 gatccagcgg accgctatct tcctcttctt caacctgttc agaaggaggc atttttttac
    32461 tgtcgatgtt gacctgaatg tctttcagcg ccaggtcatt aatacaaacg ctactgttcc
    32521 acaggcactc aagaccgacc gccagatgca gattacccgc ttttaccgcc acgcctggct
    32581 gctcataacg aacgtcagac aaggtgagat cgcgccagcc gccggtgacc ttgccaatat
    32641 ccagtcctgg cacccagcga tccgccgctt taaatacaag atgcaggccg ctggtggtgc
    32701 ccaccagaaa cgccaccgat cccagcaaca gtaagataac gataaccacg ccgaggctga
    32761 tttttttcca taaactcata attctggccc cagaccgatg taaaactgta acccgtgttc
    32821 gtctttatcc gcgaccggta cggcaaaatc gagtttgatt ggcccgaccg gcgattccca
    32881 gcgcacgccg accccggtac cggttttaaa gtcgctgcgg cgaatatcgc ttaccgcttc
    32941 gccactatcg acaaacaccg cgccccacca ttttccggtc acgttgtact ggtattccag
    33001 cgatccggtt atcaacttcg aggccccttt caggtcaccg ttggcgtatt tcggggcgat
    33061 agatttgtat ttgtagccgc gaatactgcg atcgcccccg gcgaagaaac gcagatccgg
    33121 cggtactttg tcgaaatcac cggtttcaat ccagcccagc gtgccgcgtg taacgaaacg
    33181 atggcgatcg tacagtgtgc ggatccagac gttctgcgcc tggaaaacgg agaaatcgac
    33241 atctgaaccc caggccgtgt tggagtagtc gatagagtag cgttgcgagt cgccccaggt
    33301 tggcatcagg ccaccacgag aacgcgtgcg gctaatcatc accccaggat aaaacagcat
    33361 cgtggtgttg gtaatttcac cctgggtaaa gtggtcgagg ctccagcgca ggttaatggc
    33421 acgctgccag ccgctggaga gatcccagta gcgagaagcc accagcgtag tggagtcaga
    33481 ttcggtatcg ttcaggtcag tgcgcttaaa accgccctgc accaaataat attgttccag
    33541 tggattcttc agcagcggca ttttatagct gaagtcgagg gtctgttccg gcgcggaaat
    33601 actggtactg gtggtcagac tgtgaccata agagttcatc cacggctttt tccacgtcgc
    33661 tttcacgcgc ggtcccacgt ccgtagagta accgaccccg gtttcgatgg tgttttcagt
    33721 tcgcggcgaa accacgcccg tcaagggtaa tactttcgtt tcgcgcgctt tatcaaattg
    33781 tggagccacc accaccgagt taaaccagcc ggtagcagaa agtcggcggt tcagttccgc
    33841 cagatctttc gattcgtact catcgccctc tttaaacggc accagatttt gcaggtattc
    33901 atcgcggatt tgtgatcctt caaaggtcac atgcccaaag cggtaacgtt cgccactgtt
    33961 ataatcaata tcccagaagg ctttatgcag gccgagcgca atgcccagct gcgctttggt
    34021 aaattcgcta tcgaaataac ctttacgcaa cgcaatgctg gttaaggact ttttgaaatt
    34081 ttcataatcg ccctggttca gcaccgtgcc aatagccggg cgagtatcga gcaatttcaa
    34141 atagtcttta tcggtccgcg cgccgccgcg caataccaca tcggtgccgc caattaacac
    34201 cggcacacct ggcgtgactt tggcgatcaa tacctgccgc cctttctttg gcggtggacg
    34261 gagatcaaat tcaatggtcg gctggtaata acccagcgct ttcagacctt cgcggatggc
    34321 atcatcgacg cgtgcgcgaa agcgacggtc tggcgtcact tcatcacttt caatcgtaga
    34381 aagctgcgca cgaacgttct tttccagctg tcccgataac ccctcgacct gtagacggac
    34441 gttcgcggcg acggcagatc cgcttaagca gagtaagctt acacagcata actgtcggat
    34501 atagcgcaca ttttctcctg aatatccttt tttcctgccc ctggaacgcc gttaaacggc
    34561 ttaacaaaaa tccagtaata tggattaaaa agcagactaa accccaaata tttcttatgt
    34621 tttactttag acctattcac ggtggttatt gtgtgcaaat acgcctcttg ttacaacctt
    34681 aaccccaatg accgattttc gggagagcga caccatgagt ttatttgata aaaagcatct
    34741 ggtttccccc gccgatgccc tgcctggacg taacaccccg atgcccgtag ccacgctgca
    34801 tgcggtcaac ggtcactcaa tgaccaatgt acctgacgga atggagattg ccatttttgc
    34861 gatgggttgt ttctggggag tggagcgtct gttctggcag ttacccggcg tttacagcac
    34921 cgccgcaggc tataccggag gctatacgcc aaatccgact tatcgggaag tgtgctccgg
    34981 tgatacgggt catgccgaag cggtacgcat tgtttacgat ccttccgtca tcagctatga
    35041 gcagttgcta caggtatttt gggagaatca cgatcccgcc cagggaatgc gtcagggcaa
    35101 tgaccacggc acgcagtatc gttcagcgat ttatccgctg accccagaac aggatgccgc
    35161 agctcgcgcc agtctggaac gttttcaggc ggcgatgctt gccgccgatg acgatcgtca
    35221 catcaccacg gaaatcgcta acgccacacc gttttattat gccgaagatg accaccagca
    35281 atatctgcat aaaaacccgt atggttactg tggaattggc ggaattggcg tctgtctgcc
    35341 accggaagca tagcgttacg ggtacaaatg tagattgttg ataaagtgcg ctttatttat
    35401 gccagatgcg gcgtgaatgc cttaccaggc ctacaaaatc gtccaaattc aatatattgc
    35461 agggactgcg taggcctgat cggcatagcg catcaggcag tattgcattt atcagcagtc
    35521 tgaattttaa ccctctggcg actttacagt accttacgct atactagcca ctgaaaatgc
    35581 cggttcactt tcttcgaatc ggctttcaat gtgtatttca cacaaattaa tcaacttccc
    35641 cttccgagga tctggcctga aaggtcggat aagatatgtt aaacagtatt ttagtcatac
    35701 tctgcttgat cgctgtaagt gcgttcttct cgatgtctga gatctcactt gccgcctcac
    35761 gcaaaatcaa acttaaactg ctggctgatg aaggcaatat aaatgcccaa cgcgttctga
    35821 atatgcagga aaatcccggc atgttcttta cggtggtcca aatcggtctg aacgcagttg
    35881 cgattctcgg cggtatcgtc ggtgatgcgg cattttctcc agcttttcac agcctgttct
    35941 cccgctatat gtcggcagaa ctctctgagc aactgagctt tattctctct ttctcgttag
    36001 tgactggcat gtttatcctg tttgcggatt taaccccgaa acgcatcggt atgattgcgc
    36061 cagaagcggt ggctttgcgt atcatcaacc cgatgcgctt ctgcctgtac gtttgcaccc
    36121 cgctggtgtg gttcttcaac ggcctggcga acatgatctt ccgtattttc aaactgccaa
    36181 tggtacgtaa agatgacatc acttctgatg acatctacgc ggtagtggaa gccggtgcgc
    36241 tggcgggcgt gttacgtaaa caggaacacg agctgattga aaacgtcttt gagctggaat
    36301 cccgtaccgt tccgtcttca atgacaccgc gtgaaaacgt gatttggttt gatctccacg
    36361 aagatgagca aagcctgaag aataaggtgg cggaacatcc gcactctaag ttcctcgtct
    36421 gtaatgaaga tattgaccac atcatcggtt atgtcgattc taaagacctg ctgaaccgcg
    36481 tgctggctaa ccaaagcctg gcactgaaca gcggcgtaca aattcgcaac acgctgattg
    36541 tgccggatac gttaaccctt tcagaggcgt tggaaagttt taaaaccgca ggtgaagact
    36601 tcgcggtgat catgaacgag tacgcgctgg tggtggggat catcaccctc aacgacgtga
    36661 tgaccacgct gatgggcgat ctggtcggtc aggggctgga agagcagatt gtcgcccgtg
    36721 atgagaactc atggctgatt gacggcggca ccccaattga cgacgtcatg cgcgtgctgg
    36781 atattgacga gttcccgcag tcgggcaact acgaaaccat cggaggcttt atgatgttta
    36841 tgctgcgtaa gatcccgaaa cgcaccgatt cggtgaaatt cgccggctac aaatttgaag
    36901 tggtggatat cgataactac cgcatcgacc agctgctggt gacccggatc gacagcaagg
    36961 ccaccgccct ttcgccaaaa ctgcctgacg ctaaagataa agaagaaagc gtcgcgtaac
    37021 ccccagaaac atcaacggct cctgaatcag gagccgtctt attactgcat agcactttgg
    37081 ttaagccatc tctgtttgca gacgcataac ctgacggtta acttcggaca tcactgacaa
    37141 atgcagctta tccttcactt ttgggataag aatcttaccc ttatcaaatt caaaagcgcc
    37201 aacgtccttg atgtataacc gtccacggaa caggatcttt acgtacttcg ccacctgaag
    37261 tgggttgtac cgttggaaaa ttttcattgt tatctcctgc tgagtattac gcctgtgcgg
    37321 tgccacaatc ggcccaacta ttatgaggcg caaattttaa tgcctagtga ctatagacta
    37381 tccgggcaat gtttccaccg cgtataactt tttttaccta aaggttacaa ttattcagaa
    37441 ttatcttttt accgaagcgc ggtcttcagt ataagcattc atttttcata tgatttgtgc
    37501 gcttgaccgc aaactggcat cacacttgcg ggaaattcga taaatagcac atatgattaa
    37561 aactcagacc caagtggtcg gatcacctgc atatcataag aaggaaacac catgacccta
    37621 cgcaagattc tggcactcac ctgcctgctg ttgccgatga tggcttccgc acatcagttc
    37681 gaaaccggtc agcgagtgcc gccgattggc atcaccgatc gtggcgagtt ggtgcttgat
    37741 aaagatcagt ttagctacaa aacctggaac agcgcgcagt tagtgggaaa agtgcgagta
    37801 ctgcaacata ttgctggtcg cacctctgca aaagagaaaa acgcgacgct gattgaagcg
    37861 attaaatcag cgaagttacc gcacgatcgt taccagacca ccaccattgt taacaccgac
    37921 gacgcaattc cgggttccgg catgtttgtg cgcagcagtc tggagagtaa taaaaagctt
    37981 tatccctggt cgcagtttat tgttgatagc aatggcgtcg cacgcggtgc ctggcagctg
    38041 gatgaaaaaa gttccgctgt agtggtgctg gataaagacg gtcgcgtgca atgggccaaa
    38101 gacggggcgc ttactcagga agaggtgcag caagtgatgg acctgctgca taaattaatt
    38161 aataaataga cactctgaac ccaggattca ggaacgactc gcgcggagtg taatccagcg
    38221 gtttaccctg ccagtcgtga acgtgcgctc cggcagctgc ggccacagca tgtccagcgg
    38281 cggtgtccca aatattcgtt ggtccgaagc gcgggtacag ctgcgcctgt ccttccgcca
    38341 ccaggcagaa tttcagcgaa gagccgatgg acgtggtctg atgttcgcca agctgttgca
    38401 gatactcttt cagctccgca tctgcatggg aacggctgat aaccaccagc ggcgggcgcg
    38461 catcgcggac ctgaatctgc ttgcgcacac cgcactcttc tttccaggcc ttgccttctg
    38521 ccgcgctgta cattacgttc attaccggcg catacaccac acctaaaatc ggtttgccat
    38581 ggtcaatgag cgcaatgtta acggtgaatt cgccattgcg tttaataaac tctttagtac
    38641 catccagcgg gtctaccagc cagtaacgct gccagtgctg acggacttcc caaccgggag
    38701 gatcttcttc agaaaggacc ggaatatccg gtgtcagcgt acgtaaaccg tccatgataa
    38761 cggtgtgtgc ggcaatatcc gctgccgtta ccggagaatt gtccgctttg ctgacgacgt
    38821 ccatcggttt cgtcccgtcg tagacctgca taatggcatc gcctgcattc cgtgcaagct
    38881 ggcatacttg atctaacatt tctccacctc gtctctgtga gcggtgttaa cttattgttt
    38941 tacttatacc ctatcgttaa tgaatgcgcc aactgtgata gtgtcatcat tttcaaagcg
    39001 taaaattgtg gcattcttca ctgttctata agtaagacgt ttattctccc ttttctttcg
    39061 tattcccgat gataaaagga tgtccctgat gattaagttt agcgcaacgc tcctggccac
    39121 gctgattgcc gccagtgtga atgcagcgac ggtcgatctg cgtatcatgg aaaccactga
    39181 tctgcatagc aacatgatgg atttcgatta ttacaaagac accgccacgg aaaaattcgg
    39241 actggtacgt acggcaagcc tgattaacga tgcccgcaat gaagtgaaaa acagcgtact
    39301 ggtcgataac ggcgatttga ttcaggggag tccgctggca gattacatgt cggcgaaagg
    39361 attaaaagca ggtgatattc acccagtgta taaggcatta aatacgctgg actataccgt
    39421 cggcacgctt ggcaaccatg agtttaacta cggtctggat tacctgaaaa atgcgctggc
    39481 gggagcgaaa ttcccttatg taaatgccaa cgtcattgac gccagaacca aacagccaat
    39541 gtttacaccg tatttaatta aagacaccga agtggtcgat aaagacggaa aaaaacagac
    39601 gctgaagatt ggctatattg gcgtcgtacc gccgcaaatc atgggctggg ataaagctaa
    39661 tttatccggg aaagtgacgg tgaatgatat taccgaaacc gtgcgcaaat acgtgcctga
    39721 aatgcgcgag aaaggtgccg atctcgttgt cgttctggcg cattccgggc tgtctgccga
    39781 tccgtataaa gtgatggcgg aaaactcagt ttattatctc agtgaaattc cgggtgttga
    39841 cgccattatg tttggccatg ctcacgccgt tttcccaagt aaagattttg ctgatatcga
    39901 aggagctgat atcgcgaaag gcacgctgaa tggtgttccg gcggtaatgc caggcatgtg
    39961 gggcgatcat cttggtgtgg tcgacttaca actcagtaat gacagcggta aatggcaggt
    40021 gacgcaggcg aaagcggaag ctcggccgat ttacgacatc gccaataaaa aatccctcgc
    40081 ggcggaagac agcaagctgg tagaaacact caaagccgat cacgatgcca cacgccagtt
    40141 cgtcagcaag ccaatcggta aatctgccga caatatgtat agctatctgg cgctggtgca
    40201 ggacgatccg accgtgcaag tagtgaacaa cgcgcaaaaa gcgtatgtcg aacattacat
    40261 tcagggcgat ccggatctgg caaaactgcc ggtgctttca gctgccgcac cgtttaaagt
    40321 tggtggtcgc aaaaatgacc cggcaagcta tgtggaggtg gaaaaaggcc agttgacctt
    40381 ccgtaatgcc gccgatcttt atctctaccc caatacgctg attgtagtga aagccagcgg
    40441 taaagaggtg aaagagtggc tggagtgctc cgccggacag tttaaccaga ttgatcctaa
    40501 cagcacgaaa ccgcaatcac tcatcaactg ggatggtttc cgcacctata actttgatgt
    40561 gattgatggt gtgaattatc agattgatgt tacccagcct gcccgttatg acggcgagtg
    40621 ccagatgatt aatgccaatg cggaaaggat taagaacctg acctttaatg gcaagccgat
    40681 tgatccgaac gccatgttcc tcgttgccac caataactat cgcgcttacg gcggcaaatt
    40741 tgccggtacg ggcgacagcc atatcgcttt tgcttcaccg gatgagaacc gctcggtgct
    40801 ggcagcgtgg attgctgatg agtcgaaacg tgcgggggaa attcacccgg cggcagataa
    40861 caactggcgt ttagcaccga ttgctggcga taagaaactg gatatccgtt tcgaaacttc
    40921 cccgtcagat aaagccgcag cgtttattaa agagaaaggg caatatccga tgaataaagt
    40981 cgcgaccgat gatatcgggt ttgcgattta tcaggtggat ttgagtaagt aaaacacttc
    41041 tttttcggcc tataaatcat caaccgcatc cggcatttat tggcggatgc gatgctggcg
    41101 catcttatcc gccctacaag ccatgcaccg tagaccagat aagctcagcg catccggcag
    41161 ttatgccgca cgttcatccc gcaccgccaa cacctcgggc aaattcaact caatccagtc
    41221 cgccagtgca gcaacctttt cgctcacctg ctcgcccagc ggcgtgaggc tgtattccac
    41281 atgcggcggc accaccggat acgcgatacg gttaagaaaa ccatcctgtt ctaacgcctg
    41341 taacgactgc gcaagcatct tttcactcac cccaccgatt ttgcgccgca ggtcgctaaa
    41401 gcgatgagta ccttcgcgta gcgccaccag aatcaatacc ccccaacggc tggtgacgtg
    41461 tttcaacacc tcgcgcgacg ggcactgttc cgcaaagaga ttaccctctt tcagttgttg
    41521 cgacaggcta acctgactca tttcatactt acctttttgt acgtacttac taaaagtaag
    41581 tttaggtgtt agcgtattta aacacaagac aaaacgatgg agacttccca tgatcgctat
    41641 tactggtgcc actggccaac ttggtcacta tgttattgaa tccttgatga aaacggttcc
    41701 tgccagccaa atagtggcta tcgttcgtaa tccggcaaaa gcccaggccc tggcagcaca
    41761 aggcattacc gtgcgtcagg ctgactacgg cgatgaagcc gcactgacat ctgcacttca
    41821 gggagtggaa aaactactgc tgatctcttc cagcgaagtg ggtcaacgtg ccccgcagca
    41881 tcgtaatgtt attaatgccg caaaggcggc tggcgtgaaa tttatcgctt ataccagcct
    41941 gctacatgca gatacctccc cgctcggcct cgccgatgag cacatcgaga cggataaaat
    42001 gctggctgat tctggcatcg tttacaccct gctgcgcaac ggctggtaca ccgaaaacta
    42061 cctcgccagc gccccggcag cactggaaca cggcgtattt atcggtgcgg cgggcgatgg
    42121 caaaatcgcc tcagcaacgc gggcagatta tgcggcagct gcggcacgcg tgattagcga
    42181 agccggtcac gaaggcaagg tttacgaact ggcgggcgat agtgcctgga cgttgacaca
    42241 gttagcggca gagctgacca aacagagcgg aaaatccgtt acctatcaaa atctgagcga
    42301 agccgatttc gccgcggcac tgaaaagcgt cggactgccc gacggactgg cggatatgct
    42361 ggcggattct gacgttggcg catcgaaagg tggtctgttt gataacagca aaacgcttag
    42421 caaattgatt ggccgcccaa cgacaacgtt agccgaaagc gtaagccatc tttttaatgt
    42481 taataactag ttaattaaag tggcatcctc ccgcatcctc tctaataatg acgggatgcc
    42541 gggagcaatc atgtctgctt cctgaacttt cttctgacag accaatggat gccagtaatg
    42601 attagcggcg tgctgtacgc cctgttagca gggttgatgt gggggcttat ttttgtcggg
    42661 ccgttgatcg taccggaata cccggcgatg ttgcagtcga tggggcgtta tctggcgtta
    42721 gggttaattg cgctgcccat tgcctggctg ggacgcgtgc gtctgcgtca gttggcgcgt
    42781 cgggactggc ttaccgcctt gatgctcact atgatgggca acctcattta ttacttctgc
    42841 cttgccagtg ccattcaacg tactggcgcg cctgtttcca cgatgattat cggcaccctg
    42901 ccggtggtca ttcctgtctt tgccaatctg ctttatagcc agcgcgacgg caaactcgcg
    42961 tggggaaaac tcgccccggc actgatttgt attggcatcg gcctggcgag tgtgaatatt
    43021 gctgagttaa accacggact ccccgatttt gactgggcac gttatacctc tggcatcgtg
    43081 ctagcgttag tttccgtggt ctgctgggca tggtatgccc tgcgcaacgc ccgctggctg
    43141 cgggaaaatc ccgacaaaca tccgatgatg tgggcgacgg cgcaggcgct ggtcacgctg
    43201 ccggtttctc tcatcggcta tctcgtcgcc tgttactggc tgaatataca aacgccggac
    43261 ttctccttac cttttggccc ccgtccgctg gtgtttatta gtctgatggt tgcgatagcc
    43321 gtgctttgct catgggttgg cgcactctgc tggaacgtcg ccagccagcg attaccgaca
    43381 gtgattctcg ggccgctgat tgttttcgaa acgctggcag gtttgctgta caccttttta
    43441 ctccgccagc aaatgccgcc gctaatgacg ctgagcggta tcgcgctgtt agtgattggc
    43501 gtggtcattg cggtcagagc aaaaccagaa aaacctttaa ctgaatctgt ctcagaaagt
    43561 tgacacgctg gcagtgagtt aaataagcct ctgctacgta agggttatag cttttgcctt
    43621 aaagatgcat ttaaaataca tcttatatta ttaagaatga ggtatcagct atggcttatc
    43681 gcgaccaacc tttaggtgaa ctggcgctct ctatccctcg cgcttcggct ctgtttcgta
    43741 aatatgatat ggattactgc tgtggcggta agcagacgct ggcgcgcgcg gcggcacgta
    43801 aagaactgga tgttgaggtc attgaagctg aactggcaaa gcttgctgaa caaccgattg
    43861 agaaagactg gcgtagcgcc ccgctggcag aaatcattga ccatatcatc gtgcgctacc
    43921 acgatcgtca ccgcgagcag ctgccggagc tgatcctgca agcgactaaa gtcgagcgcg
    43981 ttcacgccga caaaccgagc gtgccaaaag ggctgacaaa atacctgact atgctgcatg
    44041 aagagctttc cagccacatg atgaaagaag agcagatcct cttcccgatg atcaaacaag
    44101 gcatgggcag ccaggcaatg ggaccaatca gcgtgatgga aagcgagcac gatgaagcgg
    44161 gcgaactgct ggaagtgatt aaacacacca ccaataacgt cacaccgccg ccggaagcct
    44221 gcaccacctg gaaagcgatg tataacggta ttaatgaact gattgatgac ctgatggatc
    44281 acatcagcct ggaaaacaat gtactgttcc cacgcgcgct ggcgggtgag taatctaaaa
    44341 gctggatggc attgcgccat ccagcatgat aatgcggtta tttccgcagt tcagcagccc
    44401 gcttcttacc aataaacaac cagcccagcc ccagtgcgat aaaccacagc ggggtgacca
    44461 acagcgcctg gcgagtgtca tcttccagtg tcagcaacac gaccacgaac acaaagaacg
    44521 ccatacatac ccagcacatc agcttgccga gcggcatctt gtagatcgac ttctcatgca
    44581 gatgaggacg ctgtttgcgg taaaccaggt acgagcaaag gataattgtc cagacgaaca
    44641 taaacagaat cgcggaaacg gttgtaatca tcgtgaacgc gccaatcacg ctaggattca
    44701 catacaacat caccacgccg ccgagcagac agatacacga gaaggtcaac cctttcgcgg
    44761 gtactgcgcg cttagaaagt ttagcgaacg ctttcggtgc tacaccttcc tgcgccagac
    44821 caaacagcat acggctggta gagaagacgc cgctgttagc ggaagacgcc gcagaggtca
    44881 gcaccacaaa gttgatcacg cttgcggcag caggcagccc taccaacacg aacagttcaa
    44941 caaacgggct tttctccggg actaccgaac tccacggcgt cacggacata attacaatca
    45001 gcgcgaagac gtagaacata atgatacgga tcggaataga gttaattgca cgcggcagtg
    45061 atttctccgg atctttggtt tccgcagcgg ttgtacctac cagctcaatc cctacgaaag
    45121 cgaaaaccgc tatctggaat ccggcaaaga agccacttaa acctttcggg aaccagccgc
    45181 catcattcca caaatgcgcg aatgacgctt ccacaccagt cggtgactga aagtgcatcg
    45241 ccaccataac caggccgacg acaatcagcg acacaatggc gacgattttg atcatcgcaa
    45301 accagaactc catctcaccg aacattttca cggtggcgag attgagcgtc agcagcagca
    45361 ctatcaccgc cagcgaggcg acccagtcgg agagatcggg gaaccagaac tgagcataag
    45421 cagtgatcgc caccacgtct gccataccgg ttacaaccca gcagaaccag taagtccagc
    45481 cggtgaaata tcctgcccac ggcccgagta aatcggaagc gaagtcacta aaagatttgt
    45541 attccagatt cgaaagcagc aattccccca ttgcccgcat cacgaaaaag agcataaaac
    45601 cgatgatcat ataaacgaaa atgatcgacg gcccggcaag gctaatcgtt ttgccagacc
    45661 ccataaacaa ccccgtacca atggcaccgc caatggcaat aagctgaata tgtcggtttg
    45721 tgagattgcg ccgtagcgac tgttcagccg gagcctgatc atcggcaacg acttttacct
    45781 gatctaccat gtttttttct tcctgtacct gtctgtgttg ttcaggctct acggccttta
    45841 gtcagtctat gatacgacga atctgtatcg ggactcatcg atattaggta acaatacgcg
    45901 ggatgaatac taagatttag atctaatgtt aattttatgt ttaaagtgag tgtcatatca
    45961 cggtgataac gcgaaacagc tcacaaaaat acacgcttac ggggtctttg caacacaaaa
    46021 tagcgccgtt tggcaaactg aagggtttat tgctgaatgc ctgctcccct ctggttcgag
    46081 gggaacagaa tgcgctgctt agaggatttc cagcagttcg acttcaaaca ccagggtgct
    46141 gaacggaggg atggatgcgc ctgcgccgcg ctcgccatat gccagttcct gcgggatagt
    46201 cagttcccat ttagaaccta ccggcatcag agtcagtgct tcaatccagc cagggatcac
    46261 gccattaacc ggaaattcag cgggttcacc acgagcaacg gagctgtcaa acacggtgcc
    46321 gtcgatcagt ttaccggtgt aatgaacacg aacgcggtcg gtacgtgccg gaattgcgcc
    46381 ttcaccctgg ttgatcacgc ggaattgcag gccagattcg gtgctattca caccttcttt
    46441 tttggcgttt tcttccaggt atttcacacc ttcagcagcc atcgcctgga aacgctgacg
    46501 acgaacggca tcggcgcgct cgtggatttc acgcagcgcg cgatgcacca catcaaccgg
    46561 aacagccgga tgtttgcctt ccagcgcatc ggcaatacct gcaaccagtg cttctggcag
    46621 cagcccttcc aggccagatt cactcagttg ttgccctacc tgcaaaccaa tgccgtagct
    46681 tgcttgcgct tcgatggtgt caaaagttgg ggtggtcatc gtatttcctt tcttagggta
    46741 taaaagtagc gggcagcata tcagccacac ttctttgggt aaaactttgt cgcaggaatg
    46801 atgacaaatc ccggggaaaa agaaacaata gcaatatccc gtatgaatat aataaaggcg
    46861 ggtttaccac ggacatcata gcgttagctt attcataggc tatgattgag gaacaagacg
    46921 cggagcagga ggaaaccatg cccgggcgct ttgaactaaa accaaccctg gagaaagtct
    46981 ggcacgcgcc ggacaatttt cgcttcatgg acccgctgcc gccgatgcat cgtcggggga
    47041 tcattattgc cgccattata ttggtggtcg gatttctgct tccatctgat gatacgccca
    47101 acgcgccggt ggtgacgcgt gaagcgcagt tagatattca gtcgcaatca caaccgccga
    47161 cagaagaaca gctgcgggcg caattagtca caccacaaaa tgatcctgat caggtggctc
    47221 cggtcgctcc agaacctata caggaaagcc agccagaaga acagccgcaa actacccaaa
    47281 cacaaccatt ccagccagat agcggaattg ataatcaatg gcgctcttac cgtgtcgaac
    47341 ccggtaaaac gatggcgcag ctgttccgcg accacggact gcccgctacc gatgtctatg
    47401 caatggcgca ggtagaaggc gcgggtaagc cgctgagtaa tttgcaaaac gggcaaatgg
    47461 tgaaaatccg ccagaacgcc agcggcgtgg tgacgggctt aaccattgat acggggaata
    47521 atcaacaggt cctgttcacc cgccagccgg atggcagttt tattcgtgcg cggtagatga
    47581 agggtcaacc aaaagccagc taaggattgt ctctttgatg accttacgtc tggcttccag
    47641 tgcctggggg gaaaccatac tgatatgata aaccaggcca agcgtatgct ggttgatcaa
    47701 ataatatccg ccaagcgcag caatattaat attcacctgc aatgggtcga tatctggctt
    47761 aaaaatattt tgtttcttcc cttcatccaa taaggattcc attaactgca agtgcgcatg
    47821 gttaatttct aaaagacgct gtgattttgc ataatgcaca cccttacttt gattttcact
    47881 atgcacaatt tttaaaaacc agggattaga aatataataa tcccatgtaa aatcgattat
    47941 tttctcaatg gctttctgtg gcggaagatc tgagaaatca agggcctttt ctttttgtcg
    48001 aatatcgttc caggtatatt ccagtacttc gataaataaa ttttctttat taccaaagtg
    48061 gtgataaacc gtctgtttac tgcaccccgc ggccttgacg atattatcga ctctggcccc
    48121 ttcgtaacca tattcggcaa attcattaac cgcgcataac agcagctttt ctttcaggct
    48181 ctgtacgttg ctggtatcaa gatacataac gcttccccac gacctcttcg tggtgactat
    48241 cataacctga tttgatttca gcttcagaaa aaagggcaaa aacttgtact ttcatcaggt
    48301 tatcaaatgt cctgtgatcg ccatcgcata tcaaccaact agatggttga tctttttatc
    48361 ctccagtcgc aagctaatca tcactaagga aacaaaattc aaaaaaagag agctattgta
    48421 tgaaatccac tcgtcctgtt gccgtgatta ccggagccgc tcgtggtatt ggaaagggct
    48481 gtgcgctgga gcttgcgcgt ggcggattta atctgctgat taatgatcgt ccggatgcgg
    48541 atagcgtaga aaaattacat gccacacaac aagaatgtct ggcggaaggc gtggaagtga
    48601 tttgcttccc tgctgatgtg ggcgatctct ccctgcatga agagatgctc gacgcagcgc
    48661 aaaaccagtg gggacgtctg gactgcctgc tcaacaacgc aggcatttca gtgaaaaaac
    48721 gcggtgacct tctcgacctc gaaccagaca gcttcgacca aaatattgcc attaacaccc
    48781 gcgcaccgtt cttccttgct caggcattca gtaagcgctt actggcacag ccgaaaccgg
    48841 aagcagaact gccgcaccgc tcgattattt ttgtcagttc catcaacgcc atcatgctgg
    48901 cgatgaatcg cggcgaatat accattgcca aaactgccgt ctctgccgct gctcgtctgt
    48961 ttgctgctcg cctttgtaat gaacaaattg gcgtatatga agtgcgtcct ggtctcatca
    49021 aaaccgatat gactattccg gcaacggcct attacgacga actgattgcc aaaggtctgg
    49081 tgccgtgggg acgttggggt tatccggcgg atattgcttc cactgtccgc gcgatggcgg
    49141 aaggtaaact tatttacacc tgtggtcagg cggtcgccat cgacggcggc ttaagtatgc
    49201 cgcgcttctg aggctgaatc atgagagatc tgttacaacg cccggattta ttcagtatca
    49261 ataccgcgac actgggctat aaaacgccgc tacccgccat tattgatgcc tgcgccgcac
    49321 gcggtattgg cgcgattgcc ccctggcgca gggagttgca gagtgaagat ctccagcaaa
    49381 ccgcccgcca gcttgctgcc agtaacatga acgtttccgg tttgtgccgt agcacctact
    49441 acaccgcacc gacgctggcg gagcgcaaac tggcgattga cgataaccgc cgggcgctgg
    49501 acgacgccgc tgtactgaac gccgcctgtt atatgcaggt ggttggcggt ctgccaatgg
    49561 gaacaaaaga tctgtacgaa gcacgggaac aggtgaaaca agggattcgc cagttgctgc
    49621 cacattcgaa agaggtcggc gtgccaattg cactggagcc actgcacccg atgactgctg
    49681 ccaatcgttc ttgtctgtgc acgttacgtc aggcgctgga ctggtgtgat gaactcgatc
    49741 ccgatggcga atttggcctc ggcgtggcgg tagatgtcta ccatgtctgg tgggacccgg
    49801 atctcgccag tcagatcctg cgtgccggaa aacgcatcct cgcgtttcat gtttccgact
    49861 ggttagtgcc gaccaccgat ctggtcaatg accgtggaat gccgggagat ggtgtcatca
    49921 atattccgtc aattcgtcgg ctggttgaaa acgccggatt taatggcgct attgaactgg
    49981 aaatattctc accgtactgg tggcagaaag atattaacag cacgctggat attagcgtcg
    50041 atcgcatcgc gcattattgt taaggaatga tcatgaatga ccaacccgtt ctgttcagca
    50101 gagcggcggc ttcttgccgc ctgacattga accgtgaaga taaatgtcat gctattaatg
    50161 aagaaatgat cgaatctctc gaccattatt taaatgaaat tgaaaatgac acggcattac
    50221 gcttagtcga attaacggca accggcgata aattcttttg tgcgggtggc gatattaaat
    50281 cgtggtcggc ctattcgcca ttagatatgg gcagaaaatg gattaaacgc ggtaatgacg
    50341 tttttaatcg cctgcgaaac ttaccccaat taaccgttgc gaatctcaac ggtcatacca
    50401 tcggcggtgg tattgaactt gccttgtgct gcgatattcg tatcgctcgc cccggcgcga
    50461 aattctctaa cccggaagtg atgctcggca tggtgccagg ctggatgggc attgagcgag
    50521 tgcttaatca ggttggtcct gtggtcggtc gccagatgct gatgctgggt aaacgcctga
    50581 cggcgcagga agctcagaca gcgaatttaa ttgatgaagt ggtagaaaaa gaacaggtgg
    50641 aaagctggat ggcgaaccag ttagcgcagc tggaaaaatg tggtccggtg gcactggcac
    50701 atattaagca actgattctg gcgctggaaa ataaacacgc cgattactcg caccagttgc
    50761 tggctggatt aatgtccgcc actcaggatt gccaacaggc gacgcacgca tttgccgaaa
    50821 aagccggcgt gagcttccac aatcaataag gaaattgtat gcgtaagtta tcaaccgccg
    50881 agacactggc ggcgcaaatt caggacggcg caaccattgc cattagcggc aacggcggcg
    50941 gcatggtgga agctgaccat attctggccg ccattgaagc gcgctttctg caaaccggac
    51001 acccgcgcga tctgacatta atccactcgc tgggtattgg cgatcgcgac agcaaaggca
    51061 ctaaccgttt tgctcacgcc gaaatgctca aacgcattat tgccggacat tttacctggt
    51121 cgcccaagat gcaggaactg gtgaaaaaca atgctattga agcctactgt ttccctggtg
    51181 gcgtaattca ggcactgctg cgggagatcg gtgccggacg tccggggctt tttacccacg
    51241 ttgggctggg atcgtttgtt gatccacgca atggtggcgg taagtcgaat gaatgcacta
    51301 ccgacgacct ggtagaactg attgaaatcg acggtgagac caaacttcgt tatcgccctt
    51361 tcaaagtgga ttacgcgatt ttgcgtggca cttatgccga tccacgaggc aacgttagcc
    51421 tcgaagaaga agcgattgat atggatagct attcgatggc gctggcagca cacaacagcg
    51481 gcggcaaagt gttcgtacag gtacgcgatg tgctggaagc aggtaccatt gaaccacgtc
    51541 gggtcaagct accaggaatt ctggttgatg gcatcgttga gcaccgcgaa caaccgcaaa
    51601 cctatcttgg tggttacgac ctgaccatca gcggtcaaca tcgccgtcta agttctaacg
    51661 acgctattga actggttagt catccggtgc gtcgcctgat tgcccgtcgg gcagcgcggg
    51721 aactggtggc aggcgcttca accaactttg gctttggtat tcccggcggt attcctgggg
    51781 ttgcgctgcg cgaaggcgtg ccttatcaaa gtttgtggct gagtgtagaa cagggtgtgc
    51841 ataacggcat gatgcttgat gatgctctgt tcggctgcgc ccgtaacgcc gatgccatta
    51901 ttccatcact cgatcaattt gaattctaca gtggcggcgg catcgatatc accttcctcg
    51961 gcatgggaga gatggatcaa tacggtaacg tcaacgtatc ccatctcaat ggcaatctga
    52021 ttggccccgg cggatttctc gaaattgcac aaaacgcccg taaagtggtg ttttgcggta
    52081 cgttcgacgc caaaggcagc aagattgatg taacgccaga tggcttgcat atcgcccagt
    52141 caggtcaaat ccctaaactg gttacccagg tggaaaaaat tacttttagc gccgcctacg
    52201 cacagcaaag tggtcaggaa gtgttgtata tcactgaacg cgcagtattc cagttaacgg
    52261 cagaaggcgt tgaattaatt gaaatcgcgc cgggtgtgga gattgagcgc gacattctgc
    52321 cgtatatggc cttccgtccg attatcaggc acccacgtct gatggaaagt agcctgttta
    52381 tgccaatgga ggatgcatga gtcagcttga tgacaccatc cttgatgcac tgacgcacgt
    52441 tactttccca aagggttttg cacaggcaga acccgcatgg gttgtcacgg ttgacggcgt
    52501 tgattaccca ctctggaaaa cagatgccct ggtagtcggc agtggtgcag ccgggctacg
    52561 tgcagctgtg gaacttaaac gccgccagca aaatgtgtta atcgccaccg ccgggttata
    52621 tatggggacg tcggcatgtt ctggctctga taaacaaaca ctgtttaccg ccgctactgc
    52681 gggcaacggc gacaacttca ccaaactggc agaggcactg gcgagcggtg gggcgatgga
    52741 tcacgacacc gcttatgttg aagcggtagg ttctctgcac actcttggcg ggttgcaata
    52801 tcttggtctg gaattaccgg aagatcgcta tggcgcgatt cttcgttatc aaaccgacca
    52861 tgacgaagcc gggcgtgcaa cctcgtgtgg gccgcgtacc tcaaggttaa tggtgaaagt
    52921 gctgctggaa gaagtacagc gtcttgctat cccaatgttg accagtgcaa cagtgattaa
    52981 actgctgcat cagcgtgacg aaaacggtga agaccgtgtg gcgggggcaa tcctcgcgac
    53041 cggtcatcgc gcccataacc catgggggct ggcaattgtg actgcgccca atgtggtact
    53101 ggcaacagga gggcctggcg agctttatcg cgacagtgtt tatccacaca aatgtttcgg
    53161 ctcgctgggt ctggcgctgg aggaaggtct gacgctaacc aatctgactg aaagccagtt
    53221 tggtatcggc acaccgcgca gcacgtttcc gtggaatttg tccggcacct atgtgcaggt
    53281 gatcccgtat atctattccg tagatgctga gggtaacgag tataacttcc tcgcggatta
    53341 ctatcgcacc acccaggagc tagcttcaaa catcttccgt aaaggctatc agtggccgtt
    53401 ccacgccacg cgggtaatgg attttggctc cagcttgtta gatatggcag tagcgcaaga
    53461 gcagcaatca gggcgtcagg tatttatgga tttcaatcgc aatcctgaag cggtgccggg
    53521 tgacctgccc ttctcattag atcgactgga cgacgacgtt cgcacgtatc tggaaaataa
    53581 cgacgctctg gcaccatcgc ccatcgaacg cctgcaacga atgaatccgc tgtctatctc
    53641 gctgtataag atgcacggtt acgatctcac cacgcagcca ttgcagtttg ccatgaataa
    53701 tcagcacatg aatggcggca ttgaagtcga tatctgggga caaacatctc tgcccggttg
    53761 ttttgcggtg ggggaagttg ctggcacaca cggcgtcacc cgacctggcg gcgcggcatt
    53821 gaatgccggg caggtttttg ctgttcgtct ggcacgtttt attggttgca cgcaaaagcg
    53881 gaatattgat ggagatatag cacagctggc agctccggca ctggcttcta taagagagat
    53941 cattactcag gcgcacgata acgggaccgg gatgccgttg tcggttgtga gagaaaaaat
    54001 tcaggcacga atgtctgacc atgcgggatt tatttgccat gccgataaag tccgacgcgc
    54061 cactcgtgat gccctgctat tgaacgaatt tgtccaacga catggattgg caatcaaaca
    54121 tgtgggtgaa gttgccgagc tgtttatgtg gcggcatatg acgctgactt ctgccgcggt
    54181 attaacacaa ttaacgcatt atattgatgc tggtggtggt agccgtgggg cgcgtatggt
    54241 tattgatcca caaggcaaat gcctaccaca aactcgtcgc ggcgcaaaag aagaatggcg
    54301 ttttcgctct gaactcgctg aagacaaaaa tcacaaatta acaattcagg taatggtgcc
    54361 aacttactga tttagtgtat gatggtgttt ttgaggtgct cccgtggctt ccatctccat
    54421 cagttgtccc tcctgctcag ctactgaagg cgtggtgcgt aacggtaaaa gtactgccgg
    54481 acatcagcgc tatctctgct ctcactgccg taaaacatgg caactgcagt tcacttacac
    54541 cgcttctcaa cccggtacac accagaaaat cattgatatg gccatgaatg gtgttggatg
    54601 ccgggcaacc gcccgcatta tgggcgttgg cctcaacacg attttacgtc acttaaaaaa
    54661 ctcaggccgc agtcggtaac ctcgcgcata ca
//
LOCUS       DAPOXO010000025        54610 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPOXO010000025 DAPOXO010000000
VERSION     DAPOXO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 54610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54610
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.025"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            6..1238
                     /locus_tag="ROH59_001840"
     CDS             6..1238
                     /locus_tag="ROH59_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDX4804324.1"
                     /translation="MYRDTRREYIVRLLRNKDECSVSDLANYFSVTKETIRTDLAWLQ
                     KRGVVSRHHGGVSLKKHLMQNALSQQEYVDMSLLIKQQQQGIGYLTSLDDKGRRMVGK
                     VCVLGSFNVDIVAKVYRFPNEGETLVARETTMGPGGKGANQALAAHRAGAQIHFACKI
                     GRDQFNHFARNHIESIGIGSFTFYESELSTTGCAVIYVNDEGENMIAMSPGANHELSD
                     NDIIQLSHFIAESDVFIVQMENNLAATQLALKCAQKMQVTTILNPAPWSSDVATLLPF
                     VDIVTPNETEASAMSGMVIDNISDAVKAAKHIYNAGQCSVIITMGKRGALIYDGQQCA
                     HIPAFSAVAVDTTGAGDAFNGALAAALAKGESLVKAAWYASAFASLAVEKEGAANMPD
                     ISLVDARIQQQNVAIQTF"
     gene            1264..2187
                     /locus_tag="ROH59_001841"
     CDS             1264..2187
                     /locus_tag="ROH59_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDX4804325.1"
                     /translation="MKTIEGIIPVMLTPFTADNKIDYLGLKRLIDWYIENGADALFAV
                     CQSSEMQYLTLEERVELASFVVEYSQQRVPVIASGHISDDLEQQIQELNAMAATGIDA
                     LVLVTNHLDPHNEGTTVFLRTLDALLMSLPESMALGLYECPAPYRRLLTDEELLYCAQ
                     SGRFQILKDVSCDLPTVTRRVQLTQHTPMTIVNANAAIAWEAMLAGSKGFCGVFANFH
                     PDLYHWLWLEGKQHPEEAKQLAWFLSLSAVSENIGYPKNAKIFHQQRGTFDCVHCRVT
                     ADDVLKKYWGLEVVLKQIADAADFQRQQLKY"
     gene            2242..3195
                     /locus_tag="ROH59_001842"
     CDS             2242..3195
                     /locus_tag="ROH59_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HDX4804326.1"
                     /translation="MKRTLMSCAVASLLVSGSALAAWPEKPIQIIVPWGAGGNTDTVA
                     RLVAEGLQKELKVNVNVVNRTGGAGVVGHDAIAKAKADGYTLGIATVEITMMHHQGMT
                     ALTYQNYTPITRLAVNLGGVQVAANSQFENIVQMTDYIKANPGKLKASGSGLNSGWHL
                     NLIGMLDSMGLPPSAVTWVPSEGSSSALMELVSGGIDFTTSSPGEAKSMVDAKMVRNL
                     ATMAEKSAGLYKDLPVFQQATGYKYHLATWNALVVPAGTPEEVSQKLTAAMQAVFAQG
                     KLQEFATKQGFEVYPLYGKEMTTFMADEDARYGKLIAKIKG"
     gene            3244..3681
                     /locus_tag="ROH59_001843"
     CDS             3244..3681
                     /locus_tag="ROH59_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HDX4804327.1"
                     /translation="MRIIPITPLFLLIFAMFIFGWSITQYGGISQYGAGFMPCIISGL
                     LLFLAAIDVAIDIKHRHRNKVSLTFDEVKALLLVITVVLLFVLLLDILGFVICSFLLL
                     FILMKIRGVRLLHSVIVSISASLIIWFIFARVLLVAFPEGILF"
     gene            3691..5178
                     /locus_tag="ROH59_001844"
     CDS             3691..5178
                     /locus_tag="ROH59_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000350780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HDX4804328.1"
                     /translation="MDILIQALTYINLNAILAIIAATAFGLFVGAIPGLTATMAVALM
                     VPFTFFLDPIPALALMIAVGASSIYAGDIPGALLRIPGTPASAAYVADSNELVKQGKV
                     NRVLGLGLVSSVIGGVIGSLILMLAAPVLAKFALNFSSYEYTWLSLLGLTCATLVVGN
                     QPLKGMVTLCLGLLLACIGYDQISGVPRFTFGQISLLQGVNFIPAMIGLFAISGAIEY
                     YRDKISQVSGVVPQTQTGINLFKGMGQVIWSRKLNLGRSSIIGTLIGALPGAGADIAA
                     WISYAISKKFSRQQELYGHGSEEAIVDSSSSNNASLAGSWIPSLVFGIPGDSAAAIII
                     GVLYMKDMNPGPTLFLFQADKLYAVFILFLIANIALLPLATIAVSFIKRIIWIDKAIL
                     YPIILIFSIVGAFAIDNSGASVVVMLVMGVLGYWLQRKEYPVSPIILGMILGPMLEKN
                     LLSSMIKSNGEWLAFVERPVSMALAVCFFLVVALQGRNIYRSFSR"
     gene            5362..6126
                     /locus_tag="ROH59_001845"
     CDS             5362..6126
                     /locus_tag="ROH59_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX4804329.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLVTAVLLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     gene            complement(6240..6938)
                     /gene="thiQ"
                     /locus_tag="ROH59_001846"
     CDS             complement(6240..6938)
                     /gene="thiQ"
                     /locus_tag="ROH59_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HDX4804330.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGLLTLDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAAQQKKMHAIAHQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSSSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTDELL
                     SGKASASALLGIKG"
     gene            complement(6922..8532)
                     /gene="thiP"
                     /locus_tag="ROH59_001847"
     CDS             complement(6922..8532)
                     /gene="thiP"
                     /locus_tag="ROH59_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HDX4804331.1"
                     /translation="MATRRQPLIPGWLIPGISAATLVVAVALAAFLALWWNAPQGDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRQVLLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLWQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTALIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKIPGRNVKTD"
     gene            complement(8508..9491)
                     /gene="thiB"
                     /locus_tag="ROH59_001848"
     CDS             complement(8508..9491)
                     /gene="thiB"
                     /locus_tag="ROH59_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HDX4804332.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     TEAVNVPGGWKNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYEDPRT
                     STPGLGLLLWMQKVYGDNAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     regulatory      complement(9522..9621)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(9655..11310)
                     /gene="sgrR"
                     /locus_tag="ROH59_001849"
     CDS             complement(9655..11310)
                     /gene="sgrR"
                     /locus_tag="ROH59_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SgrR"
                     /protein_id="HDX4804333.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQETTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLTEIADEPAGGLMLKGPQGEEQEIESRLEEG
                     CYYLLFDNRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARP
                     THCEKPAGLEHLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIES
                     DIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     gene            11399..11530
                     /gene="sgrT"
                     /locus_tag="ROH59_001850"
     CDS             11399..11530
                     /gene="sgrT"
                     /locus_tag="ROH59_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HDX4804334.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY"
     gene            complement(11637..12242)
                     /gene="leuD"
                     /locus_tag="ROH59_001851"
     CDS             complement(11637..12242)
                     /gene="leuD"
                     /locus_tag="ROH59_001851"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDX4804335.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR"
     gene            complement(12253..13653)
                     /gene="leuC"
                     /locus_tag="ROH59_001852"
     CDS             complement(12253..13653)
                     /gene="leuC"
                     /locus_tag="ROH59_001852"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDX4804336.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     gene            complement(13656..14747)
                     /gene="leuB"
                     /locus_tag="ROH59_001853"
     CDS             complement(13656..14747)
                     /gene="leuB"
                     /locus_tag="ROH59_001853"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDX4804337.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            complement(14747..16318)
                     /gene="leuA"
                     /locus_tag="ROH59_001854"
     CDS             complement(14747..16318)
                     /gene="leuA"
                     /locus_tag="ROH59_001854"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDX4804338.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIDKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            complement(16410..16496)
                     /gene="leuL"
                     /locus_tag="ROH59_001855"
     CDS             complement(16410..16496)
                     /gene="leuL"
                     /locus_tag="ROH59_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HDX4804339.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     gene            17154..18098
                     /gene="leuO"
                     /locus_tag="ROH59_001856"
     CDS             17154..18098
                     /gene="leuO"
                     /locus_tag="ROH59_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HDX4804340.1"
                     /translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     ALGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQTWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
     gene            complement(18259..18297)
                     /locus_tag="ROH59_001857"
     CDS             complement(18259..18297)
                     /locus_tag="ROH59_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804341.1"
                     /translation="MKRNDKILHYRG"
     gene            18416..20140
                     /gene="ilvI"
                     /locus_tag="ROH59_001858"
     CDS             18416..20140
                     /gene="ilvI"
                     /locus_tag="ROH59_001858"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HDX4804342.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTSGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHLQLKEAVEALNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGARFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTNGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPQELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            20143..20634
                     /gene="ilvN"
                     /locus_tag="ROH59_001859"
     CDS             20143..20634
                     /gene="ilvN"
                     /locus_tag="ROH59_001859"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDX4804343.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            20646..20732
                     /locus_tag="ROH59_001860"
     CDS             20646..20732
                     /locus_tag="ROH59_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HDX4804344.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            20814..21818
                     /gene="cra"
                     /locus_tag="ROH59_001861"
     CDS             20814..21818
                     /gene="cra"
                     /locus_tag="ROH59_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HDX4804345.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            22420..22878
                     /gene="mraZ"
                     /locus_tag="ROH59_001862"
     CDS             22420..22878
                     /gene="mraZ"
                     /locus_tag="ROH59_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDX4804346.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            22880..23821
                     /gene="rsmH"
                     /locus_tag="ROH59_001863"
     CDS             22880..23821
                     /gene="rsmH"
                     /locus_tag="ROH59_001863"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDX4804347.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            23818..24183
                     /gene="ftsL"
                     /locus_tag="ROH59_001864"
     CDS             23818..24183
                     /gene="ftsL"
                     /locus_tag="ROH59_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDX4804348.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            24199..25965
                     /gene="ftsI"
                     /locus_tag="ROH59_001865"
     CDS             24199..25965
                     /gene="ftsI"
                     /locus_tag="ROH59_001865"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HDX4804349.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLTLSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTVPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     gene            25952..27439
                     /gene="murE"
                     /locus_tag="ROH59_001866"
     CDS             25952..27439
                     /gene="murE"
                     /locus_tag="ROH59_001866"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDX4804350.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSAHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TDVNYHDSGATICFSSSWGDGEIESRLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVVVVTDDNPRTEEPRAIINDILAGMLDAGYAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            27436..28794
                     /gene="murF"
                     /locus_tag="ROH59_001867"
     CDS             27436..28794
                     /gene="murF"
                     /locus_tag="ROH59_001867"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDX4804351.1"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLVNLKAVPGRLFPIKLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDCVLSVGK
                     QSHAISTASGVGEHFSDKTALIARLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     gene            28788..29870
                     /gene="mraY"
                     /locus_tag="ROH59_001868"
     CDS             28788..29870
                     /gene="mraY"
                     /locus_tag="ROH59_001868"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDX4804352.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            29873..31189
                     /gene="murD"
                     /locus_tag="ROH59_001869"
     CDS             29873..31189
                     /gene="murD"
                     /locus_tag="ROH59_001869"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDX4804353.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGGLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWVNDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            31189..32433
                     /gene="ftsW"
                     /locus_tag="ROH59_001870"
     CDS             31189..32433
                     /gene="ftsW"
                     /locus_tag="ROH59_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HDX4804354.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            32430..33497
                     /gene="murG"
                     /locus_tag="ROH59_001871"
     CDS             32430..33497
                     /gene="murG"
                     /locus_tag="ROH59_001871"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDX4804355.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEVGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRAARA"
     gene            33551..35026
                     /gene="murC"
                     /locus_tag="ROH59_001872"
     CDS             33551..35026
                     /gene="murC"
                     /locus_tag="ROH59_001872"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDX4804356.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            35019..35939
                     /gene="ddlB"
                     /locus_tag="ROH59_001873"
     CDS             35019..35939
                     /gene="ddlB"
                     /locus_tag="ROH59_001873"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDX4804357.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQSAGLPVAPWVALTRAEFEKGLNDKQLAEISSLGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPAGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            35941..36771
                     /gene="ftsQ"
                     /locus_tag="ROH59_001874"
     CDS             35941..36771
                     /gene="ftsQ"
                     /locus_tag="ROH59_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HDX4804358.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            36768..38030
                     /gene="ftsA"
                     /locus_tag="ROH59_001875"
     CDS             36768..38030
                     /gene="ftsA"
                     /locus_tag="ROH59_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDX4804359.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            38091..39242
                     /gene="ftsZ"
                     /locus_tag="ROH59_001876"
     CDS             38091..39242
                     /gene="ftsZ"
                     /locus_tag="ROH59_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDX4804360.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            39343..40260
                     /gene="lpxC"
                     /locus_tag="ROH59_001877"
     CDS             39343..40260
                     /gene="lpxC"
                     /locus_tag="ROH59_001877"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HDX4804361.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            40490..41002
                     /gene="secM"
                     /locus_tag="ROH59_001878"
     CDS             40490..41002
                     /gene="secM"
                     /locus_tag="ROH59_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308128.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HDX4804362.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLETNTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLS"
     gene            41064..43769
                     /gene="secA"
                     /locus_tag="ROH59_001879"
     CDS             41064..43769
                     /gene="secA"
                     /locus_tag="ROH59_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDX4804363.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEIEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            43829..44227
                     /gene="mutT"
                     /locus_tag="ROH59_001880"
     CDS             43829..44227
                     /gene="mutT"
                     /locus_tag="ROH59_001880"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HDX4804364.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFSGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRVYVE"
     gene            complement(44315..44512)
                     /gene="yacG"
                     /locus_tag="ROH59_001881"
     CDS             complement(44315..44512)
                     /gene="yacG"
                     /locus_tag="ROH59_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HDX4804365.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(44522..45265)
                     /gene="zapD"
                     /locus_tag="ROH59_001882"
     CDS             complement(44522..45265)
                     /gene="zapD"
                     /locus_tag="ROH59_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HDX4804366.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDSENGQVPERLDFELACC"
     gene            complement(45265..45885)
                     /gene="coaE"
                     /locus_tag="ROH59_001883"
     CDS             complement(45265..45885)
                     /gene="coaE"
                     /locus_tag="ROH59_001883"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDX4804367.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            45910..45954
                     /locus_tag="ROH59_001884"
     CDS             45910..45954
                     /locus_tag="ROH59_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804368.1"
                     /translation="MIIKTLKMSARKRN"
     gene            46110..47153
                     /gene="guaC"
                     /locus_tag="ROH59_001885"
     CDS             46110..47153
                     /gene="guaC"
                     /locus_tag="ROH59_001885"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDX4804369.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQRW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     gene            complement(47188..48390)
                     /gene="hofC"
                     /locus_tag="ROH59_001886"
     CDS             complement(47188..48390)
                     /gene="hofC"
                     /locus_tag="ROH59_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HDX4804370.1"
                     /translation="MASKQLWRWRGITGDGNAQDGMLWAESRALLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGVAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGW
                     LLVLFGFLLAIANKLLMRHPTRLIARQKLLLRIPIMGSLMRGQKLTQIFTILTLTQSA
                     GISFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNAGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(48380..49765)
                     /gene="gspE"
                     /locus_tag="ROH59_001887"
                     /pseudo
     CDS             complement(48380..49765)
                     /gene="gspE"
                     /locus_tag="ROH59_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414649.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
     gene            complement(49775..50215)
                     /gene="ppdD"
                     /locus_tag="ROH59_001888"
     CDS             complement(49775..50215)
                     /gene="ppdD"
                     /locus_tag="ROH59_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HDX4804371.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLNTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     gene            complement(50419..51312)
                     /gene="nadC"
                     /locus_tag="ROH59_001889"
     CDS             complement(50419..51312)
                     /gene="nadC"
                     /locus_tag="ROH59_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDX4804372.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     PLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     gene            51400..51951
                     /gene="ampD"
                     /locus_tag="ROH59_001890"
     CDS             51400..51951
                     /gene="ampD"
                     /locus_tag="ROH59_001890"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HDX4804373.1"
                     /translation="MLLEQGWLAGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDRYPDIANNMTGHCDIAPD
                     RKTDPGPAFDWARFRALVSKETT"
     gene            51948..52802
                     /gene="ampE"
                     /locus_tag="ROH59_001891"
     CDS             51948..52802
                     /gene="ampE"
                     /locus_tag="ROH59_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HDX4804374.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     CMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHAHATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHALDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(52845..54215)
                     /gene="aroP"
                     /locus_tag="ROH59_001892"
     CDS             complement(52845..54215)
                     /gene="aroP"
                     /locus_tag="ROH59_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HDX4804375.1"
                     /translation="MEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAG
                     PGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLY
                     VLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIKV
                     IAVVAMIIFGAWLLFSGNGGPQASVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLEL
                     VGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFH
                     ELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVN
                     TILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGV
                     VTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKTA
                     KAVKAH"
BASE COUNT        12868 a        13319 c        14928 g        13495 t
ORIGIN      
        1 gacttatgta tcgggatacc cgtcgtgaat atattgtccg gttacttcgc aacaaggatg
       61 agtgcagtgt tagcgattta gctaactatt tttctgttac caaagagacg attcggacag
      121 atttagcgtg gttgcaaaag cgtggtgtag tgagtcgtca tcatggaggc gtctcattga
      181 aaaaacattt aatgcaaaat gcgctttcgc aacaagagta tgtcgatatg agtttgctta
      241 tcaagcaaca acagcagggt attggctatt taacctcgct tgatgataaa ggacgccgaa
      301 tggtaggtaa agtttgtgtg ttaggatcat ttaacgtcga tattgtggcg aaagtgtatc
      361 gcttcccgaa tgaaggcgaa acgttagtgg ccagggaaac taccatgggg ccggggggta
      421 aaggcgcgaa tcaggcacta gccgctcatc gggcaggtgc gcaaatacac ttcgcctgta
      481 agattggtcg cgatcagttt aatcattttg cccgcaatca tattgagtcc attggtattg
      541 gttcatttac tttttatgag tctgaactat ctaccaccgg ttgtgcggtc atttatgtaa
      601 atgatgaagg tgaaaacatg attgctatgt ctccaggggc aaatcatgaa ttaagtgata
      661 acgatattat tcaactttct cactttatag ccgagtccga tgtattcatt gtacagatgg
      721 aaaataatct tgccgctact caactggcat taaaatgtgc tcaaaaaatg caggtgacaa
      781 cgattttaaa tcctgcaccg tggtccagtg atgtcgccac attattacct tttgttgata
      841 ttgtgacgcc aaatgaaacc gaagcatcgg cgatgtcagg tatggtaatt gacaatattt
      901 ctgatgctgt gaaggctgcg aagcatattt ataatgccgg gcaatgttca gtaattatta
      961 cgatgggaaa acgaggtgca ttaatttatg acgggcaaca atgtgcgcat attccggcat
     1021 tttcggcagt cgctgtagat acaacaggtg cgggtgatgc gtttaatggc gcgctcgccg
     1081 ccgcactggc gaagggagaa tcacttgtta aagcagcctg gtatgccagc gctttcgctt
     1141 cgctggcagt agaaaaagaa ggggcagcca atatgcctga tatctctctg gtggatgcca
     1201 gaattcagca gcagaatgtt gccattcaga ctttctgatg tttcactgaa cgaaggatga
     1261 aatatgaaaa caattgaagg gattattccg gtaatgctaa cgccttttac ggcggataat
     1321 aaaattgatt acctgggtct taaacggcta attgactggt atatcgaaaa cggtgccgac
     1381 gcgttatttg ccgtgtgtca gtccagtgaa atgcagtatt taactttaga agagcgcgtg
     1441 gagctggcga gctttgtggt tgaatatagc caacaacgag taccggttat tgcgtccggg
     1501 catatttctg atgatctgga acagcaaatt caggagctca atgctatggc ggcaacgggc
     1561 attgatgcgc tggtgttagt gacgaatcat cttgatccac ataacgaagg taccacggta
     1621 ttcctccgta cgcttgatgc gctattgatg tcattacccg aaagtatggc gctgggtctg
     1681 tatgaatgcc cggccccgta tcgccgctta ttaaccgatg aggaactgct ttactgcgca
     1741 caaagcgggc gttttcaaat cttaaaagac gtcagttgtg atctacctac agtgacgcga
     1801 cgggtgcaat taactcagca cacgccaatg acgattgtta atgctaatgc tgccattgcc
     1861 tgggaggcga tgcttgcagg ttcgaaaggt ttttgtggcg tctttgccaa ctttcatcct
     1921 gacttgtatc actggctttg gcttgaagga aaacaacacc ctgaagaggc aaaacaactc
     1981 gcctggtttt tatcgctgag tgccgtcagt gaaaatattg gctatccgaa aaatgccaaa
     2041 atatttcatc agcagcgagg aacatttgac tgtgttcatt gccgggtaac ggctgacgat
     2101 gtgctgaaaa aatattgggg gctggaggtg gtgctaaaac aaattgctga tgccgcagat
     2161 ttccagcgtc aacaactcaa atattaatat ccgacagcac ttgctgttat taaaaaataa
     2221 ttaagacagg agtctacaaa tatgaaacga accctgatga gttgtgccgt tgcttcactg
     2281 ctggtttcag gttccgcgct ggctgcatgg ccagaaaaac caatccaaat cattgtcccc
     2341 tggggcgcgg gaggaaatac cgatacggtt gcacgcctgg tggcagaagg gctgcaaaaa
     2401 gagttgaaag tgaatgtcaa cgtggtgaat cgcacgggag gtgctggggt ggttggccat
     2461 gatgccattg cgaaagctaa agcggatggc tataccctgg gaattgcgac ggtagaaatc
     2521 accatgatgc accatcaggg gatgacggcg ttaacgtatc agaactacac gccaattaca
     2581 cggctggcag tgaatctggg aggcgtgcaa gtcgcagcaa attcgcagtt cgaaaatatc
     2641 gtccagatga ccgactacat caaggcgaat ccaggtaagt taaaagcatc gggtagcggg
     2701 ttaaattccg gctggcatct gaacttgata ggtatgctcg acagtatggg gcttccgcct
     2761 tctgccgtga cctgggtgcc ttctgaaggt tccagttctg cactgatgga actggtttcc
     2821 ggtggtatag attttacaac gtcatcacca ggcgaagcga aaagtatggt cgatgccaaa
     2881 atggtgcgta atttagcgac catggcagaa aaatcagcag ggctttataa agatcttcca
     2941 gtattccaac aagcaactgg ctataaatat catttggcga catggaatgc cttagtggtt
     3001 ccggcgggta ctcctgaaga ggtctcacaa aaattaactg ccgctatgca ggcagtgttt
     3061 gcgcagggga aattacaaga attcgctacc aaacagggtt tcgaagttta cccgctgtat
     3121 ggcaaagaga tgacgacatt tatggcagat gaagatgcca gatacggaaa attaatagcc
     3181 aaaatcaaag gttaatcaga cagggcggtg aatatatcgc cgccaaatta cagggatagc
     3241 attatgcgca taataccgat aacgccgtta tttctgctga tttttgccat gtttattttt
     3301 ggctggagca taacgcaata tggaggcata tcgcagtatg gcgctggatt tatgccttgc
     3361 atcatcagtg gattgttgtt gtttttagcg gctattgatg tagcgataga tattaaacac
     3421 cggcaccgta acaaagtttc tttaactttt gatgaagtga aagcactttt actggttatt
     3481 acagtggtac tactgtttgt attactgtta gatattctcg gctttgtgat ttgctcattt
     3541 ttgttgcttt ttattttaat gaaaatacga ggtgtcagac ttttgcattc cgttatcgtt
     3601 tcgatatcgg catctcttat tatctggttc atttttgcca gagtgttgtt ggtcgccttt
     3661 cctgaaggaa tcttgtttta aggatgcaat atggatattt tgattcaggc actaacgtat
     3721 attaatttga atgccattct ggccattatt gctgctacgg cctttgggtt atttgtgggg
     3781 gccatccctg gattgaccgc aacgatggcg gttgcactaa tggtgccttt taccttcttt
     3841 cttgatccta ttcccgccct ggcattaatg attgccgttg gtgcgtcatc catttatgcc
     3901 ggagatatcc ccggcgcact tttgcgtata ccagggacac ctgcttcggc ggcttatgtt
     3961 gctgattcaa atgaactggt caagcaaggg aaggtgaatc gcgtattggg acttgggctg
     4021 gtgagttcgg tcattggtgg cgtgattgga tcacttattt tgatgttggc tgcgcctgta
     4081 ctggcgaaat ttgcccttaa ttttagttct tatgaataca catggctttc tcttttaggc
     4141 ttaacttgcg cgactctggt tgtgggtaat caaccactga aaggcatggt gaccttatgt
     4201 ttgggattat tactggcgtg tatcggttat gatcaaatat ccggagttcc acgttttacg
     4261 tttggtcaaa tcagcctgtt acaaggggtg aactttatcc cggcgatgat tggtctgttc
     4321 gcgatatccg gcgcaattga atattatcgt gacaaaatta gccaggtaag tggtgttgtg
     4381 ccacaaacgc aaacggggat taatttattc aagggaatgg ggcaggtgat ttggtcacga
     4441 aaattaaatc ttggccgaag tagtattatc ggtacgctta tcggagcatt acccggcgct
     4501 ggagcggata ttgctgcgtg gataagttac gccatttcaa aaaaattctc tcgccagcag
     4561 gagttatatg ggcatggatc tgaggaggca attgttgatt cctcgagcag taacaacgcc
     4621 agtctggcgg ggagttggat cccttcatta gttttcggta ttccgggcga ttctgccgct
     4681 gcaattatca tcggcgtgct ctatatgaag gatatgaatc cagggccgac attatttctg
     4741 ttccaggcag ataaacttta tgccgtattt atcttgtttc tgatcgccaa tattgcatta
     4801 ctaccgttag ccacaattgc ggtcagtttc atcaaacgca tcatctggat tgataaagcg
     4861 attctgtacc cgattattct gattttcagt attgtcggtg catttgctat cgataactcg
     4921 ggtgcttctg tcgttgtcat gttggtcatg ggggttcttg gatactggtt acaacgtaag
     4981 gaatacccgg tttcgcccat tattctgggg atgattcttg ggccaatgtt ggaaaaaaac
     5041 ttattatctt caatgattaa gtctaatggc gaatggctgg cgtttgttga gcgcccggta
     5101 tctatggcac tggctgtctg tttctttttg gttgtcgcgt tgcaaggacg caatatctac
     5161 cgttcattta gccgttaatc cgttgttttc agaccatcca agttgtggat ggtctgcctt
     5221 cccctaagta aaatcctgcg tgactgctaa atttatactc taaatgattc gcgttgcagg
     5281 aatatattca tacaaagaat agattgacct gaataccacc actttgcaca atccacgacg
     5341 aattcatcaa ccgggcacat tatgcaagca ttgctggaac actttattac ccaatccacc
     5401 gtgtattcat tgatggcggt ggtgttggtg gcctttctgg agtcgctggc gctggtcggt
     5461 ttgattctgc ccggtacggt gctgatggcg gggctgggag cgttgattgg cagcggtgag
     5521 ttaagtttct ggcacgcctg gctggcaggg atcgtcggtt gcctgctggg cgactggatc
     5581 tccttctggc tgggctggcg ttttaaaaag ccgttgcatc gctggtcatt tctgaagaag
     5641 aacaaagcat tactcgataa aaccgaacat gcgctgcatc agcacagcat gttcaccatt
     5701 ctggtcggtc gttttgtcgg cccgacgcgt ccgctggtgc caatggtggc agggatgctg
     5761 gatctgccgg tggcgaaatt tattacgcca aatattatcg gctgcctgtt atggccaccg
     5821 ttttacttcc tgccggggat tctggcgggt gcggcgatcg atattcctgc cgggatgcag
     5881 agcggtgagt ttaaatggtt gctgctggtg acggcggtat tgttgtgggt tggtggctgg
     5941 ctgtgctggc ggttatggcg cagcggtaaa gcgactgacc gtttgagtca ttatttgtcc
     6001 cgcggtcgtt tgttgtggct gacgccgttg atttctgcca tcggcgtggt ggcgctggtg
     6061 gtgttaattc gccacccgtt gatgccggtg tatatcgata ttttgcgtaa agtggttggg
     6121 gtttagagga tagccttgtg cgggttgcct gatgcgacgc ttgctgcgtc ttatcaggcc
     6181 tacaaaacgc actacctgta ggtcggataa ggcgttcacg ccgcatccga cagtgcatat
     6241 taacctttaa ttcccaacag cgccgaagca ctcgccttac cgctcaacaa ctcatcggtc
     6301 ttaccctgcc aggcgatacg cccgtcggcg accaccaccg agcgcgtggc gatccgcgcc
     6361 gcatcttcca cactgtgcga caccatcaag agcgtcattt tttgctgttg gcagctcgaa
     6421 ctcaccagcg tcagcatctc ctgacgtagc gccggatcga gtgcggaaaa cggttcatcg
     6481 agcaataaaa tgggctgttc gcgtaccaga caacgcgcta acgccacgcg ctgtcgctga
     6541 ccgccggaaa gctcgccagg taaccgcgcc attaaattat caatccccat ctggtgggca
     6601 atcgcgtgca ttttcttctg ctgcgccgca tttagtttca accccggatt tagccccagc
     6661 ccgatgttct gcgcgaccgt caggtggctg aacaggttgt tctcctgaaa cagcattgac
     6721 accggacgac gtgacggtgg cgttgtggtg tgatctacgc cgtcgagagt cagcaaaccg
     6781 ctggctggcg tcagaaaacc ggcgatcaaa tttagcaggg tgcttttacc cgcgccgctt
     6841 ggcccgagga tcgccacctg ctcgccgcgt tccaccgtta agctaaaacg catcggcaaa
     6901 tggtggtaaa gccaggtgat atcagtcagt tttaacattt cgccccggta ttttttcaat
     6961 cacggtaaac agcagaaaac agagcagcag cagaattaac gcggtgaccg cgccgtcctg
     7021 gctgcgatag gagccaattt gctgatagag ataaaacggc agggtacgga aatcatcgtt
     7081 accgaacaat gccaccacgc caaaatcacc aatcgacagc acacaagcaa aggccagcgc
     7141 ctgcgccagt ggacgtttca gagcgcgcag ctccaccact tttaagcgtg accagccttc
     7201 aatgcccagc gactgacaca acatgctgta gcgggcggtg atatcgcgca tcgggttttc
     7261 cagtactttc agcgcataag ggattgccat taacgcattg gtgaaaatca caatgccgtc
     7321 agcagattgt ggcaggccga tagtgttgtt gagcagtaaa aagaagcccg tagccagtac
     7381 aatccccggc atggcgagga tcaacatgcc gctcatctcc agcgcctgac ccgccagcat
     7441 tttctgccgt gcccgaagtt cgcgactgct ccatagcagc atcatggtca gcactacgca
     7501 caatacgcct gccgccagcg caatacgcaa cgaggtccac agcgcctgcc acagcaccgg
     7561 ttgtgccagc acttccggca actggcgatt taccccatcg acgatcaccg ccagtaacgg
     7621 tggcagcaac agcagcagcg ccagcacaat taacgccgtg tcgcaaatgc gactatgcag
     7681 acgatcgtcc gggtcgcgcc agccttgcag cagtgtggta ccgggcgcaa tggccttact
     7741 caatcgctga ctcaacagca ccagcccgag gcagcacacc atctggatca gcgccagcat
     7801 tgccgcgcgg gcaggatcgt agtcgtaact cagcgcctga tagattgcca gctcgatagt
     7861 ggtcgcctgc ggaccgccgc ccagcgatag cacggtggcg aagctggcga aacagagcat
     7921 aaagataagc gcagcaaccg gcgggatttg tcgccgtaac cacggccatt cgacgaagcg
     7981 gaagaagtgc cagccgcgca tcccaagttg tgcggcaagc tgacgttgtt cgccgggaat
     8041 gttttccagt gcctggagta ataaacggct agccatcggc agattaaaaa acacatgggc
     8101 cagcaaaatg ccttgcaggc cgtagggcga aaaggtccac tccagaccaa gtgattgcca
     8161 gagcgaggcc agccagccct ggcgaccata gacgctaaga atgccgaaaa cggcgaccag
     8221 caccgggagg atcaaggtca ttgcgcacag acgcaacagc acctgtcgcc caggaaagcg
     8281 cctgcgatag agcgcgcggg cgaggaatat tgcgggtacg acagagagca gcgccgagag
     8341 aaacgcctgc cagaaggaga agcgcaccac atgccacaga tagctgtcct gccagactgc
     8401 cacccagtca ccctgcggcg cgttccacca cagggcgaga aacgccgcca gcgcaaccgc
     8461 taccaccagt gtggcggcgc ttattcctgg aattaaccag ccgggaatta acggctgacg
     8521 gcgcgttgcc attcgctaat ccatgcctga cgttgtgccg ccacttcggc gggcgtgaac
     8581 tctagcgtgg tggctggttt ggtcaattgt tcaaatcctg caggcagagt gacgtttgct
     8641 accggataca tccagttgcc ggttgggatc gcattctgaa aagccggaga aaccataaac
     8701 tggaggaatt tttgcgccag ctctggctgc ttgctggcag cggtgcgggc ggcaacttcc
     8761 acctgcagat agtgaccttc gctgaagttc gcggcggcgt agttatcttt cttctcttcg
     8821 agaatgtgat aagccggaga ggtggtgtaa ctcagtacca gatcgctttc gccttttaaa
     8881 aacaggccgt aggcttcgct ccagccttta gtgaccgtga cagttttctt cgccagtttc
     8941 tgccaggctt gcggggcgtt atcgccatag actttttgca tccatagcaa cagacccaga
     9001 cctggtgtac tggtacgcgg atcttcataa atcacccgcc agttttgatc gctctcaacc
     9061 agttctttca ggctttgcgg cggatttttc agtttgttct tgtcatagac gaaggcgaaa
     9121 tagccatagt caaacggcac aaaggtgtca tttttccagc cgccgggaac gtttacagcc
     9181 tctgtcgcga cgccgctttt ggcaaacaac ccggttttgc tggcggcgtc cagcaggttg
     9241 ttatccagcc ccagcaccac atcggctttg ctgtttttgc cttccatccg tagacggttg
     9301 agcagcgaaa cgccatcttc cagcgccacc agtttcagtt cgcaattaca gtctgcttca
     9361 aaggcttttt tgactaccgg accaggtccc cagtcagcgg caaaggaatc gtaggtataa
     9421 acagtcagaa caggtttagc gaaaacaggc gctgtgcaca gcaacagcag gggaagacat
     9481 ttttttaaca ctttgcacct cacaaaagag tggcaaagga cttgagaagg agcctcaaat
     9541 cccttcgccg gcgttatccg gatcaggttc gacgggtatt ttctcagcgc acgcggctgc
     9601 gtggcacccc gttgagaacg gcgttagtgt agtgattttg ttatcaacca gcaatcatgg
     9661 atccggtggt gcaaaccacg ctgatttaaa atcgaaccag ccgagggtgt tcatgcgcag
     9721 gccgcgcata ctgcgttgcc cctgaatgat cagccagtgg tggataagtg gcaccattgc
     9781 tttgctggcg accagttgct ggcaccagtt cgccaggttc atttcgccat tgcgccagcg
     9841 ggcggcgtcg gcttgccagt cgatcggaat acagtgttgg agtagcggca cctcgcacaa
     9901 gtgcgcgaac agcgaaaaat ccagcggcag cgtaaagttg gcgctgttaa gccagatatc
     9961 gctctcgatc tctccttcat gccactgatc gtagctgatc tctttgattt ccagcgtgac
    10021 ctggtgactc gccagaatct gctgcatgat cccggcaatc actcgatgtt caatatgatc
    10081 ctgataaaag gtcagggtga gatgttccag cccggcgggt ttttcgcaat gtgtcgggcg
    10141 ggcatggtgc cagcggggga gcagtccata agccgggaac cagagttgct ggtattgttc
    10201 ctcggcgaaa tagaccagat tcgtcggaga aagcacatag cttacccagt ccctgacttg
    10261 ctgattcgcc ccgcggtggg tgcggttgtc gaacagtaaa taatagcaac cttcctccag
    10321 gcggctttca atctcttgtt cctcgccctg cggccctttc agcatcagcc ctccggctgg
    10381 ctcgtcggca atttccgtta gaacccagac gttaacttcg tcgattaatg cccggtaacc
    10441 gaagaagtca tcgaatgcct gaattttcag ttgattggtg ctgttgcgga tcaccgcata
    10501 cggaccggtg ccgatgggat ggctggcaaa gttactgagg gtttcccatt cgcgcggcag
    10561 gatcattgcc ggaacttgcc ccagcagtaa cggcaaccag cggtccggtt gcgtgagatg
    10621 gatatccagc gtccagggcg tcggcgacac aatgtcagca atatgcgaat agagcggaag
    10681 cgtattgatt cgttttaaag aggcgatcac atcgtccatt tccagttcac gaccatggtg
    10741 aaaatggact cctggacgca aaaagaaacg ccagtgaagc ggtgatattt gctgccagtg
    10801 gtgtgcgatg tctgcttcca gttccccatt ttcctcattt atgcgcgtta gcgaactgaa
    10861 gatttgccgg gcgatatggg tttcagaacg gcgcaatgcg ctgccaggta gcagattacg
    10921 caacggacga tagtagagca cgcgcaggat gtgccgcccc tggcggaagc tgcggcccag
    10981 atgagaaacc agcatttgcc gcacagtcgc tttgtcgcca accaactgca ctagttggtc
    11041 gatacgatcc tgctccagca ggtcttccgc tcgctgttgc tgaagcgcca gcccggtata
    11101 gaggaatgtc agacgcgagc gtttaccgcg cccgacttcc gcttcccacg tcagccagcc
    11161 gcgatcctgc atggtgttga gcagggtgcg catatgacga cgcgagcaac tcagtaacgc
    11221 tgccagttcg ttgagcgtgg tctcctgaga tttaccctcg cagcattgcc acaggcggat
    11281 gaactgttgt tgcagacgag cagatggcat aaaaggggaa ctcctgcgca aaagacagca
    11341 attttatttt ccctatatta agtcaataat tcctaacgat gaagcaagga ggtgccccat
    11401 gcgtcagttt tatcagcact attttaccgc gacagcgaag ttgtgctggt tgcgttggtt
    11461 aagcgtccca caacgattaa ccatgcttga agaactgatg caatgggagg ggagtcattc
    11521 tgactactga tttgcggaca tcatgtgtga ctgagtattg gtgttaatcg ccacgccagc
    11581 agtgattatc tgctggcttt tttcttttgg cgattgagtg ccggacggtg tacaaactaa
    11641 cgcataaacg ccggttgctt ctcttcataa gacgcaatag catcgtcgtg ctgcagagtc
    11701 aggccgatgc tgtccagacc gttcatcatg cagtggcggc ggaaggcatc gatggtaaag
    11761 cgataagttt tctctcccgc tttcacctct tgcgcttcca ggtctacatc aaaatgaatc
    11821 cccggattgg ctttcaccag cgcaaacagc tcatccactt ctgcatcgct taatttcacc
    11881 ggcagcagct ggttgttaaa gctattgccg tagaagatgt cagcaaaact cggcgcaatc
    11941 accaccttaa aaccgtaatc ggtcaatgcc cacggcgcgt gctcacgcga ggaaccgcag
    12001 ccgaagtttt ctcgtgccag caaaatggaa gcgccctgat actgcgggaa gttcagcacg
    12061 aagtccgggt ttggctgttg gcctttttca tccagaaaac gccagtcgtt aaacagatgc
    12121 gcgccaaaac ccgtacgggt cactttctgc aaaaactgtt tcgggatgat tgcatcggta
    12181 tcgacattgg cggcatccaa cggaaccacc aggcctgtgt gtttgataaa tttctctgcc
    12241 atggtgtgct ccttatttaa tgttacgaat gtcggcgaaa tgtccggtca cagccgcggc
    12301 ggcagccatt gccgggctga ccagatgcgt gcgcccgccg cgcccctggc ggccttcaaa
    12361 gttacggttg ctggtggagg cgcaacgttc gcccggattc agacggtcgt tattcatcgc
    12421 cagacacatt gagcaacctg gcaagcgcca ttcaaaacca gcttcgataa aaattttgtc
    12481 cagaccttcc gcttccgcct gggctttaac cggaccggag ccgggaacca ccagcgcttg
    12541 tacgcctggc gcgactttcc ggcctttggc gatttccgct gccgcgcgta aatcttcaat
    12601 acgcgagtta gtacaggaac caataaacac tttgtcgata gccacttctg tcagcggaat
    12661 acccggtttc agccccatat aggccagcgc tttttctgcc gacgcgcgtt caaccggatc
    12721 ggcaaacgaa gccggatcgg gaatattgtc gttcacagaa atcacctggc ctggattggt
    12781 gccccaggtg acctgcggcg aaatctcttc tgcttgcaga gtgacaacgg tatcgaaagt
    12841 tgctccttcg tcggtttgca gggttttcca gtaggcaacg gcgtcgtcga aatctttacc
    12901 tttcggcgca tgcagacggc ctttaacata gttaaaggtg gtttcgtccg gcgcaaccag
    12961 accggctttt gcgcccattt cgattgccat attgcacagg gtcatacgac cttccatgct
    13021 taaatcacgg attgcttcgc cgcaaaattc caccacatgc ccggtaccgc ctgcgctgcc
    13081 ggttttacca ataattgcca gcacgatatc ttttgcggta atgcccggcg cggctttgcc
    13141 ctggacttca attttcatgg tcttcgcccg gccctgtttc agggtttgcg ttgccagtac
    13201 gtgttcaact tcggaagtgc cgataccaaa ggccagtgcg ccaaacgcgc cgtgggtggc
    13261 ggtatgtgag tcgccgcaga caatggtcat ccccggcaag gtcacaccct gttccggccc
    13321 cattacgtgg acgatcccct gatacgggtg attcaggtca tacagctcga cgccaaattc
    13381 tttgcagttt ttgatcagct cctgcatctg gatgcgcgcc atttcaccgc aggcattaat
    13441 gtctttcgtc tgggtagaga cgttgtgatc catggtggcg aaggttttgc ccggctgacg
    13501 taccgggcga ccgtgggcgc gcagaccatc gaacgcctgc ggtgaggtca cttcatgcac
    13561 caggtggcgg tcgatatata acagcggggt ttcgttttcg gcttcgtaca ctacgtgagc
    13621 gtcgaataat ttttcgtata acgtcttagc catgattaca ccccttctgc cacatagcgg
    13681 gcaatgatat cgcccatttc atcggtacta acggcggcag cgccacgggc taaatccccg
    13741 gtgcgaatgc cttcttctaa tgcgcggtta atggcgcgtt caatggcgga agccgcatca
    13801 tcggcatcca ggctgtaacg cagcagcagc gccagcgaca gaatttgtgc aatcgggttg
    13861 gcgatatttt tacctgcgat atcgggtgcc gagccgcccg ccggttcata cagaccaaaa
    13921 ccttgctcgt tcaggctggc ggaaggcaac atccccattg agccagtgat cattgcgcac
    13981 tcatcagaca gaatgtcgcc aaacaggttg gagcacagca agacgtcaaa ctgtgatgga
    14041 tctttaatca gctgcatggt ggcgttgtcg atgtacatat gcgccagttc gacgtccggg
    14101 tattccgtgg cgatctcgtt aacgatctcc cgccataaaa tagaggattg cagcacgttg
    14161 gctttgtcga ttgaggtgac tttgtggcga cgcttgcggg cagattcaaa tgcgatgcgg
    14221 gcaatacgct cgatctcaaa acggtggtac acctcggtat caaacgcttt ttcatattgt
    14281 ccgctacctt cgcggccttt tggctgaccg aaatagatgc cgccggtcag ttcgcgcaca
    14341 cacaggatgt caaagccgtt tgcggcaatg tcagcacgca gcggacagaa tgcttccagc
    14401 ccctgataca gttttgccgg acgcagattg ctgaataatt tgaagtgctt acgcaaaggc
    14461 agcagtgcgc cgcgttctgg ttgctggtct ggcggcaaat gttcccactt cggaccacct
    14521 accgagccaa acagcacggc atcggcttgc tcacaacctt caaccgtcgc aggcggcagc
    14581 ggctgcccgt gattatcaat ggctgcgccg cctacatcgt aatggctggt ggtgatacgc
    14641 atcgcaaatc ggttgcgcac ggcatccagc actttcagcg cctgggtcat cacttccgga
    14701 ccaataccgt cccccggcaa tacggcaata tggtaattct tcgacatcac acggtttcct
    14761 tgttgttttc gttgtgttga gctttgcgtt gcaactcttt ttcgacttct gcggcacgcc
    14821 agatattgtt cagtacgtgc accatggctt tggcggagga ctcgacaata tcggtggcca
    14881 ggccgacgcc gtggaagcgg cgaccgttgt agttggcgac aatatccacc tgacccagcg
    14941 catctttacc gtgacctttg gcggtcaggc tgtatttcac cagttcgacg ttatagtcag
    15001 tgatgcggtt tatcgcctgg tagacggcat caaccgggcc gttgccgtta gcggcttctg
    15061 ctttaacttc ttcgccacag gccagtttga cggcggcagt ggcaatatcg ttagaacctg
    15121 actgcacgct gaagtaatcc agacggaaat gctccggctc ttcttgctgc ttatcgatga
    15181 aggccagcgc ctccagatcg taatcaaaca cctggccttt tttgtccgcc agcttcagga
    15241 aagcgtcgta caggttgtct aaattatatt cactttcttt atatcccatc tcatccatgc
    15301 gatgtttcac cgccgcacgc cccgaacgag aggtcagatt cagctggatt tggttcagac
    15361 caatagattc tggtgtcatg atttcgtagt tttcgcggtt tttcagtaca ccatcctggt
    15421 ggataccgga ggagtgtgcg aatgcgccgc tgccaacaat ggctttgttt gccgggatcg
    15481 gcatattaca aatctggcta actaactggc tggtgcgcca tatctcctgg tgattgatgg
    15541 cggtgtggac gttgagaata tccttacgaa ctttgatcgc catgatgact tcttcaaggg
    15601 aacagttacc ggcacgctcg ccgatcccgt tcattgcgcc ttctacctgc cgtgctccgg
    15661 catgtaccgc cgccagtgag ttgccgaccg ccaggcccaa atcgtcgtgg gtatgtacgg
    15721 aaataatggc tttgtcgatg ttgggtacgc gttcatacag gccgctgatg attccggcga
    15781 actcaaatgg catggtgtag cccacggtgt ccggaatgtt gatggtggtg gcaccggcat
    15841 taatcgccgc ttcgaccact cgcgccagat cggcaattgg ggtgcgtccg gcatcttcgc
    15901 aagaaaattc aacatcatcg gtgtaattac gggcgcgttt caccatatag atagcgcgtt
    15961 cgatcacttc gtccagcgtg ctgcgcagct tggtggcgat gtgcattggc gaagtggcaa
    16021 taaaggtatg aatacggaag gcttcggcga ctttcaggga ttcggctgcc acgtcgatat
    16081 ctttctccac gcagcgagct aacgcgcata cacggctgtt tttaacctgg cgagcgatgg
    16141 tctgcactga ttcaaaatca cccggcgaag agacggggaa accgacttcc atcacgtcaa
    16201 cacccatacg ctcaagggcc agcgcaattt gcagtttttc tttcacactc aagcttgcct
    16261 gtaacgcctg ttcaccgtcg cgcaatgtgg tatcgaaaat aatgacttgc tggctcatgg
    16321 tttgggtcct tgtctctttt tgagcgcctc gcttcgggca taaaaaaacc cgcgcaatgg
    16381 cgcgggtttt tgtttgactg cgtgctggct taatgctgga tgccgctcac tcgtctaccg
    16441 cgcaaagaag atgcgtttag tagtagtaga ccgataaagc gaacgatgtg agtcattaaa
    16501 tcagctccag atgaatgcga tatgctttta gagttactgg atacaaaaac ggatgtcaac
    16561 cctgaagcaa taaaaacgtc acgccattgt gagttcggca tccgtaaaat tagctaattg
    16621 tgctgcggtg gttaaaacaa gcgatattaa tttctgctta accgccgatg cttttcatcg
    16681 gttgacatat ttcagaataa ttttttgcat ctaatcaacg agggaaaggg ggataaaatg
    16741 cacgcgttac aaaacctatc ctgatgattt gtattgaatt atatgttttg cgaatttttt
    16801 gatattcatt tggtgaatat tattgatcaa ttaatgttaa gaattaatgc attaaacata
    16861 taaattaatt attaaaaagc acatttaatc cattttgtgg atgattgagt attcgtggta
    16921 gttatgatta gattgttttc gcaacaaaaa aattatggat tattatgctg tagtaaacga
    16981 ctctttgctc ggcagtggat tctgttttta tcagaacccg tatctttatg ttttcctaat
    17041 tttactcatt ttgctttttc ttattttata tgcatgataa atcatattct cgaggattat
    17101 ttctctgcat tccaataagg gaaagggagt taagtgtgac agtggagtta agtatgccag
    17161 aggtacaaac agatcatcca gagacggcgg agttaagcaa gccacagcta cgcatggtcg
    17221 atctcaactt attaaccgtt ttcgatgccg tgatgcagga gcaaaacatc acccgtgccg
    17281 ctcatgctct gggaatgtcg caacctgcgg tcagtaacgc tgttgcacgc ctgaaggtga
    17341 tgtttaatga cgagcttttt gttcgttatg gtcgtggtat tcaaccgact gctcgcgcat
    17401 ttcaactttt tggctcagtt cgtcaggcat tgcaattagt acaaaatgaa ttaccaggtt
    17461 caggctttga gcctgccagt agtgaacgtg tatttcatct ttgtgtctgc agcccgttag
    17521 acagcattct gacctcgcag atttataatc acattgagca gattgcgcca aatatacatg
    17581 ttatgttcaa gtcttcatta aatcagaaca ctgaacatca gctgcgttat caggaaacgg
    17641 agtttgtgat tagttatgaa gacttccatc gtcctgaatt taccagcgtg ccattattta
    17701 aagatgaaat ggtgttggta gccagcaaaa atcatccaac aattaaaggc ccgttactga
    17761 aacatgatgt ttataacgaa caacatgcgg cggtttcgct cgatcgtttc gcgtcattta
    17821 gtcaaacctg gtatgacacg gtagataagc aagccagtat cgcgtatcag ggcatggcaa
    17881 tgatgagcgt acttagcgtg gtgtcgcaaa cgcatctggt tgctattgcg ccgcgttggt
    17941 tggctgaaga gttcgctgaa tccttagagt tacaggtatt accgctgccg ttaaaacaaa
    18001 acagcagaac ctgttatctc tcctggcatg aagctgccgg gcgcgataaa ggccatcagt
    18061 ggatggaaga gcaattagtc tcaatttgca aacgctaact gaatgcagaa taggtcagac
    18121 atcaatgtct ggtttattct gcatttttta ttgaatgtag aattttattc tgaatatttg
    18181 tgctctctat tttaggatta attaaaaaaa tagagaaatt gctgtaagtt gtaggattca
    18241 gccgatttat tatcaatttc atcctctgta atggaggatt ttatcgtttc ttttcacctt
    18301 tcctcctgtt tattcttatt accccgtgtt tatgtctctg tctgccaatt gcttaagcaa
    18361 gatcggacgg ttaatgtgtt ttacacattt tttccgtcaa acagtgaggc aggccatgga
    18421 gatgttgtct ggagccgaga tggtcgtccg atcgcttatc gatcagggcg ttaaacaagt
    18481 attcggttat cctggaggcg cggtccttga tatttacgat gcattgcata ccgtgggtgg
    18541 tatcgatcat gttttagttc gccatgagca ggcggcggtg catatggccg atggtctggc
    18601 gcgcgcgacc ggggaagtcg gcgtcgtgct ggtaacgtcg ggtccagggg cgaccaatgc
    18661 gattactggc attgccaccg cttatatgga ttccattcca ttagttgtcc tttccgggca
    18721 ggtagcgact tcgttgatag gttatgatgc ctttcaggag tgcgacatgg tggggatttc
    18781 tcgcccggtg gttaaacaca gttttctggt taagcaaacg gaagacattc cgcaggtgct
    18841 gaaaaaggct ttctggctag cggcaagtgg tcgtcctgga cccgtggtcg ttgatttacc
    18901 gaaagatatt ctaaatccgg cgaacaaatt accctatgtc tggccggagt cggtcagtat
    18961 gcgttcttac aatcccacga cctccgggca taaagggcaa attaagcgcg ctctgcaaac
    19021 gctggtggcg gcaaaaaaac cggttgtcta cgtaggcggt ggggcaatca cggcgggctg
    19081 ccatctgcag ttgaaagaag cggtggaggc gttgaatctg cccgttgttt cctctttgat
    19141 ggggctgggg gcgtttccgg caacgcatcg tcaggcactg ggcatgttgg gaatgcacgg
    19201 tacctacgaa gccaatatga cgatgcataa cgcggatgtg attttcgccg tcggggcacg
    19261 ttttgatgac cgaacgacga acaatctggc aaaatactgc ccaaatgcca ctgttctgca
    19321 tatcgatatt gatccaacct caatttctaa aaccgtgact gctgatatcc cgattgtggg
    19381 ggatgctcgc caggtcctag aacaaatgct tgaactcctg tcgcaagaat ccgcccatca
    19441 accgctggat gagatccgcg actggtggca gcagattgaa cagtggcgcg ctcgtcagtg
    19501 cctgaaatat gacactcaca gtgaaaagat taaaccgcag gcggtgatcg agactctttg
    19561 gcggttgact aatggggacg cttacgtgac gtccgatgtc gggcagcacc agatgtttgc
    19621 tgcgctttat tatccattcg acaaaccgcg tcgctggatc aactctggcg gcctcggcac
    19681 gatgggtttt ggtttacctg cggcactggg cgtcaaaatg gcgttgccag aagaaaccgt
    19741 ggtttgcgtc actggtgacg gcagtattca gatgaacatc caggaactgt ctaccgcctt
    19801 gcaatacgag ttgcccgtac tggtggtgaa tctcaataat cgctatctgg ggatggtgaa
    19861 gcagtggcag gacatgatct attccggccg tcattcacaa tcttatatgc agtccttacc
    19921 agacttcgtc cgtctggcgg aagcctatgg tcacgtcggg atccagatct ctcatccgca
    19981 agaactggaa agcaaactta gcgaggcgct ggaacaggtg cgcaataatc gcctggtgtt
    20041 tgttgatgtt accgtcgatg gcagtgagca cgtctacccg atgcagattc gcgggggcgg
    20101 aatggatgaa atgtggttaa gcaaaacgga gagaacctga ttatgcgccg gatattatca
    20161 gtcttactcg aaaatgaatc aggcgcgtta tcccgcgtga ttggcctttt ttcccagcgt
    20221 ggctacaaca ttgaaagcct gaccgttgcg ccaaccgacg atccgacatt atcgcgtatg
    20281 accatccaga ccgtgggcga tgaaaaagtg cttgagcaaa tcgaaaagca attacacaag
    20341 ctggtcgatg tcttgcgcgt gagcgagttg gggcagggcg cgcacgttga gcgggaaatc
    20401 atgctggtga aaattcaggc cagcggttac gggcgtgacg aagtgaaacg taatacggaa
    20461 atattccgtg ggcaaattat cgatgtcaca ccctcgcttt ataccgttca attagcaggc
    20521 accagcgata agcttgatgc atttttagca tcgattcgcg atgtggcgaa aattgtggaa
    20581 gttgctcgct ctggtgtggt cggactttcg cgcggcgata aaataatgcg ttgagaatga
    20641 tctcaatgcg caatttgcag cccaacatgt cacgttgggc tttttttgcg aaatcagtgg
    20701 gaacctggaa taaaagcagt tgccgcagtt aattttctgc gcttagatgt taatgaattt
    20761 aacccatacc agtacaatgg ctatggtttt tacattttac gcaaggggca attgtgaaac
    20821 tggatgaaat cgctcggctg gcgggagtgt cgcggaccac tgcaagctat gttattaacg
    20881 gcaaagcgaa gcaataccgt gtgagcgaca aaaccgttga aaaagtcatg gctgtggtgc
    20941 gtgagcacaa ttaccacccg aacgccgtgg cagctgggct tcgtgctgga cgcacacgtt
    21001 ctattggtct tgtgatcccc gatctggaga acaccagcta tacccgcatc gctaactatc
    21061 ttgaacgcca ggcgcggcaa cggggttatc aactgctgat tgcctgctcg gaagatcagc
    21121 ccgacaacga aatgcgctgt attgagcacc ttttacagcg tcaggttgat gccattattg
    21181 tttcgacgtc gttgccacct gagcatcctt tttatcaacg ctgggctaac gacccgttcc
    21241 cgattgtcgc gctggaccgc gccctcgatc gtgaacactt caccagcgtg gttggtgccg
    21301 atcaggatga tgccgaaatg ctggcggaag agttacgtaa gtttcccgcc gagacggtgc
    21361 tttatcttgg cgcgctgccg gagctttctg tcagcttcct gcgtgaacaa ggcttccgta
    21421 ctgcctggaa agatgatccg cgcgaagtgc atttccttta tgccaacagc tatgagcggg
    21481 aggcagctgc ccagttattc gaaaaatggc tggaaacgca tccgatgccg caggcgctgt
    21541 tcacaacgtc gtttgcgttg ttgcaagggg tgatggatgt cacgctacgt cgcgacggca
    21601 aactgccttc tgacctggca attgccacct ttggcgataa cgaactgctc gacttcttac
    21661 agtgcccggt gctggcagtg gctcaacgtc accgcgatgt cgcagaacgt gtgctggaga
    21721 ttgtcctggc gagcctggac gaaccgcgta agccaaaacc tggtttaacg cgcattaaac
    21781 gtaatctcta tcgccgcggc gtgctcagcc gtagctaaac cgcgaacaaa agtacgcgcc
    21841 aggtgaattt ctctctggcg cgttgagtac gggaatggac atcaatatcc ttaaagtaaa
    21901 taagactatt cctggctatt attgataaat gcttttaaac ccgcccgtta attaactcac
    21961 ctgctgaaat gcacaataat taaatgatat tgacagcgcg tttttgcatt attttgttac
    22021 atgcagagat gaattgccga tttaacaaac acttttcttt gtttttgcgc aaacctgctg
    22081 gcatcaagcg ccacacagac gcaacaggga ctgttaacca gagaagatat gtcctaaaat
    22141 gccgctcgcg tcgcaaactg acactttata tttgctgtgg aaaatagtga gtcattttaa
    22201 aacggtgatg acgatgaggg attttttctt acagctattc ataacgttaa tttgcttcgc
    22261 acgttggacg taaaataaac aacgctgata ttagccgtaa acatcgggtt ttttacctcg
    22321 gtatgccttg tgactggctt gacaagcttt tcctccgctc cgtaaactcc ttttagtggg
    22381 aaattgtggg gcaaagtggg aataaggggt gaggctggca tgttccgggg agcaacgtta
    22441 gtcaatctcg acagcaaagg gcgcttatca gtgcctaccc gttatcggga acagctgctt
    22501 gagaacgctg ccggtcaaat ggtttgcacc attgacattc atcacccgtg cctgctgctt
    22561 taccccctgc ctgaatggga aattatcgag caaaaattat cgcgtctgtc gagcatgaac
    22621 ccggttgagc gccgtgtgca gcgcctactg ttaggtcatg ccagcgaatg tcagatggat
    22681 ggcgcaggtc gattgttaat cgcgccagta ctgcggcaac atgccgggct gacaaaagaa
    22741 gtgatgctgg ttggacagtt caacaagttt gagctgtggg atgaaacaac ctggcatcaa
    22801 caggtcaagg aagatatcga cgcagagcag ttggctaccg gagacttatc ggagcgactg
    22861 caggacttgt ctctataaaa tgatggaaaa ctataaacat actacggtgc tgctggatga
    22921 agccgttaat ggcctcaata tccgtcctga tggcatctac attgatggga cttttggtcg
    22981 cggtggtcac tcacgtctga tcctctcgca gcttggcgaa gaggggcgtt tgctggcgat
    23041 cgatcgcgac ccgcaggcta tcgccgttgc gaagactatt gatgatccgc gcttctccat
    23101 catccacgga cctttctctg cgctgggcga atatgttgcc gagcgcgatc ttatcggcaa
    23161 gatcgacggc attctcctcg atcttggcgt ctcttcaccg caacttgatg atgctgaacg
    23221 cggcttttcc tttatgcgcg atggtccgct ggacatgcgt atggacccaa cccgtgggca
    23281 gtcagccgct gaatggctac aaaccgcaga agaagccgat atcgcctggg tattgaaaac
    23341 ctatggtgaa gagcgttttg ccaaacgcat tgctcgcgcc attgtcgagc gtaaccgcga
    23401 acagccgatg acccgcacca aagaactggc ggaagtcgtg gctgccgcaa cgccggtgaa
    23461 agataagttt aaacatcccg cgacccgtac cttccaggcg gtgcgcattt gggtaaacag
    23521 tgaactggag gagatagagc aggcgctaaa aagctcgctc aatgtgctgg ccccgggggg
    23581 gcggctttcg atcatcagct tccactcact tgaagaccgc attgtgaaac gttttatgcg
    23641 tgaaaacagc cgcggtccgc aagttccggc agggttaccg atgacagaag agcagctcaa
    23701 aaaactgggg gggcgtcagt tgcgagcact aggtaagttg atgccgggcg aagaagaggt
    23761 ggctgagaac cctcgtgccc gtagttcagt tctgcgtatt gcagagagga cgaacgcatg
    23821 atcagcagag tgacagaagc tctaagcaaa gttaaaggat cgatgggaag ccacgagcgc
    23881 catgccttgc ctggcgttat cggtgacgat cttttgcgat ttgggaagct gccactctgc
    23941 ctgttcattt gcattatttt gacggcggtg accgtggtaa ccacggcgca ccatacccgt
    24001 ttactgaccg ctcagcgcga acaactggtg ctggagcgag atgctttaga cattgaatgg
    24061 cgcaacctga tccttgaaga gaatgcgctc ggcgaccata gccgggtgga aaggatagcc
    24121 acggaaaagc tgcaaatgca gcatgttgat ccgtcacaag aaaatatcgt agtgcaaaaa
    24181 taaggataaa cgcgacgcat gaaagcagcg gcgaaaacgc agaaaccaaa acgtcaggaa
    24241 gaacatgcca actttatcag ttggcgtttt gcgttgttat gcggctgtat tctcctggcg
    24301 ctggcttttc tgctcggacg cgtagcgtgg ttacaagtta tctccccgga tatgctggtg
    24361 aaagagggcg acatgcgttc tcttcgcgtt cagcaagttt ccacctcccg cggcatgatt
    24421 actgaccgtt ctggtcgccc gttagcggtg agtgtgccag taaaagcgat ttgggctgac
    24481 ccgaaagaag tgcatgacgc tggcggtatc agcgtcggtg accgctggaa ggcgctggct
    24541 aacgcgctca atattccgct ggatcagctc tcagcccgca ttaacgccaa cccgaaaggg
    24601 cgctttattt atctggcgcg tcaggtaaac cctgacatgg cggactacat caaaaaactg
    24661 aaactgccgg gaattcatct gcgtgaagaa tctcgccgtt attatccatc cggcgaagtg
    24721 actgctcacc tcatcggctt tactaacgtc gatagccaag ggattgaggg ggtcgagaag
    24781 agtttcgata aatggcttac cgggcagccg ggtgagcgca ttgtgcgtaa agaccgctat
    24841 ggtcgcgtaa ttgaagatat ttcttctact gacagccagg cagcgcacaa cctgacgctg
    24901 agtattgatg aacgcctgca ggcgctggtt tatcgcgaac tgaacaacgc agtggccttt
    24961 aacaaggctg aatctggtag cgccgtgctg gtggatgtca acaccggtga agtgctggcg
    25021 atggctaaca gcccgtcata caacccaaat aatctgagcg gcacgccgaa agaagcgatg
    25081 cgtaaccgta ccatcaccga cgtgtttgaa ccgggctcaa cggttaaacc gatggtggtg
    25141 atgaccgcgt tgcaacgtgg cgtggtgcgg gaaaactcgg tactcaatac cgttccttat
    25201 cgaattaacg gccacgaaat caaagacgtg gcacgctaca gcgaattaac cctgaccggg
    25261 gtattacaga agtcgagtaa cgtcggtgtt tccaaactgg cgttagcgat gccgtcctca
    25321 gcgttagtag atacttactc acgttttggg ctgggaaaag cgaccaattt ggggttggtc
    25381 ggagaacgca gtggcttata tcctcaaaaa caacggtggt ctgacataga gagggccacc
    25441 ttctctttcg gctacgggct aatggtaaca ccgttacagt tagcgcgagt ctacgcaact
    25501 atcggcagct acggcattta tcgcccactg tcgattacca aagttgaccc cccggttccc
    25561 ggtgaacgtg tcttcccgga atccattgtt cgcaccgtgg tgcatatgat ggaaagcgtg
    25621 gcgctaccgg gcggcggcgg cgtgaaggcg gcgattaaag gctatcgtat cgccattaaa
    25681 accggtaccg cgaaaaaggt cgggccggat ggtcgctaca tcaataaata tattgcttat
    25741 accgcaggcg ttgcgcctgc gagtcagccg cgcttcgcgc tggttgttgt tatcaacgat
    25801 ccgcaggcgg gtaaatacta cggcggcgcc gtttccgcgc cggtctttgg tgccatcatg
    25861 ggcggcgtat tgcgtaccat gaacatcgag ccggatgcgc tgacaacagg cgataaaaat
    25921 gaatttgtga ttaatcaagg cgagggtaca ggtggcagat cgtaatttgc gcgaccttct
    25981 tgctccgtgg gtgccagacg caccttcgcg agcactgcga gagatgacac tcgacagccg
    26041 tgtggctgcg gcgggcgatc tctttgtagc tgtagtaggt catcaggcgg acgggcgtcg
    26101 atatatcccg caggcgatag cgcaaggtgt ggctgccatt attgcagagg cgaaagatga
    26161 ggcgaccgac ggtgaaatcc gtgaaatgca cggcgtaccg gtcatctatc tcagccagct
    26221 caacgagcgt ttatctgcac tggcgggccg cttttaccat gaaccctctg acaatttacg
    26281 tctcgtgggc gtaacgggca ccaacggcaa aaccacgact acccagctgt tggcgcagtg
    26341 gagtcaactg cttggcgaaa ccagcgcggt aatgggcacc gttggtaacg gcctgctggg
    26401 gaaagtgatc ccgacagaaa atacaaccgg ttcggcagtc gatgttcagc atgagctggc
    26461 ggggctggtg gatcagggcg cgactttttg cgcaatggaa gtttcatccc acgggctggt
    26521 tcaacaccgt gtggcggcat tgaaatttgc ggcgtcggtc tttaccaact taagccgcga
    26581 tcaccttgat tatcatggtg atatggaaca ctacgaagcc gcgaaatggc tgctttattc
    26641 tgcacatcat tgcggtcagg cgattattaa cgccgacgat gaagtgggcc gccgctggct
    26701 ggcaaaactg ccggacgcgg ttgcggtatc aatggaagat catatcaatc cgaactgtca
    26761 cggacgctgg ttgaaagcga ccgacgtgaa ctatcacgac agcggtgcga ccatttgctt
    26821 tagctcgagt tggggcgatg gggaaattga aagtcgcctg atgggcgcat tcaacgtcag
    26881 caacctgctg ctggcgctgg cgacactgct ggcactcggc tatccgctgg ctgatttgct
    26941 gaaaaccgcc gcgcgtctgc aaccggtttg cggacgtatg gaagtgttca ctgcaccagg
    27001 caaaccgacg gtggtggtgg attacgcgca tacgccggat gcactggaaa aagccttaca
    27061 ggcggcgcgc ctgcactgtg cgggcaagct gtggtgcgtc tttggctgcg gtggcgatcg
    27121 tgataaaggc aaacgtccac tgatgggcgc aattgctgaa gagtttgctg acgtggtggt
    27181 ggtgacggac gataacccgc gtaccgaaga gcctcgtgcc atcatcaacg atattctggc
    27241 gggaatgtta gatgccggat atgccaaagt gatggaaggc cgtgctgaag cggtgacttg
    27301 cgccgttatg caggctaaag agaatgatgt ggtactggtc gcgggcaaag gccatgagga
    27361 ctaccagatt gttggcaatc agcgtctgga ctactccgat cgcgtcacgg tggcgcgtct
    27421 gctgggggtg attgcatgat tagcgtaacc cttagccaac ttaccgatat tctcaacggt
    27481 gaactgcaag gtgcagatat tacccttgat gctgtaacca ctgacacgcg aaaactgacg
    27541 ccgggctgcc tgtttgttgc cctgaaaggc gaacgtttcg atgctcatga ttttgccgac
    27601 caggcgaaag ctggcggcgc aggcgcacta ctggttagcc gtccgctgga tattgatctg
    27661 ccgcagttaa tcgtcaagga tacgcgtctg gcgtttggtg aactggctgc atgggttcgc
    27721 cagcaagttc cggcgcgcgt ggttgctctg acaggttcct ccggcaaaac ctccgttaaa
    27781 gagatgacgg cggcaatttt aagccagtgc ggcaacacac tttatacggc aggcaatctc
    27841 aataacgaca tcggtgtacc gatgacgctg ttgcgcttaa cgccggaata cgattacgca
    27901 gttattgaac ttggcgcgaa ccatcagggt gaaattgcct ggactgtgag tctgactcgc
    27961 ccggaagcgg cgctggtcaa caacctggca gcggcgcatc tggaaggttt tggctcgctt
    28021 gcgggtgtcg cgaaagcgaa aggtgaaatc tttagcggcc tgccggaaaa cggtatcgcc
    28081 attatgaacg ccgacaacaa cgactggttg aactggcaga gcgtaattgg ctcacgcaaa
    28141 gtgtggcgtt tctcacctaa tgccgccaac agcgatttca ccgccaccaa tatccatgta
    28201 acctcgcacg gtacggaatt taccctgcaa acccctacag gtagcgtcga tgttctgctg
    28261 ccgttgccgg ggcgtcacaa tattgcgaat gcgctggcag ccgctgcgct ctccatgtct
    28321 gtgggcgcaa cgcttgatgc tatcaaagcg gggctggtaa atctgaaagc tgttccaggc
    28381 cgtctgttcc ccataaaact ggcagaaaac cagttgctgc tcgacgactc ctacaacgcc
    28441 aatgtcggtt caatgaccgc cgctgttcag gttctggctg aaatgccggg ctaccgcgtg
    28501 ctggtggtgg gcgatatggc ggaactgggc gctgaaagcg aagcctgcca tgtacaggtg
    28561 ggcgaagcgg caaaagctgc tggtattgac tgcgtgttaa gtgtgggtaa acaaagccat
    28621 gctatcagca ccgccagcgg cgttggcgaa catttttccg ataaaactgc gcttatcgcg
    28681 cgtcttaaat cactgattgc tgagcaacag gtaattacga ttttagttaa gggttcacgt
    28741 agtgctgcca tggaagaggt agtacgcgct ttacaggaga atgggacatg ttagtttggc
    28801 tggccgaaca tttggtcaaa tattattccg gctttaacgt cttttcctat ctgacgtttc
    28861 gcgccatcgt cagcctgctg accgcgctgt tcatctcatt gtggatgggc ccgcgtatga
    28921 ttgctcattt gcaaaaactt tcctttggtc aggtggtgcg taacgacggt cctgaatcac
    28981 acttcagcaa gcgcggtaca ccgaccatgg gcgggataat gatcctgacg gcgattgtga
    29041 tctccgtgct gctgtgggct tacccgtcca atccgtacgt ctggtgcgta ctggtggtgc
    29101 tggtaggtta cggtgttatt ggctttgttg atgattatcg caaagtggtg cgtaaagaca
    29161 ccaagggcct gattgcccgt tggaagtatt tctggatgtc ggtcattgca ctgggtgttg
    29221 ccttcgcgct gtaccttgcc ggcaaagaca cgcccgcaac gcagttggtg gttccgttct
    29281 ttaaagatgt gatgccgcaa ctggggctgt tctacattct gctggcttac tttgtcattg
    29341 tgggtactgg caacgcggta aacctgaccg atggtctcga cggtctggca attatgccga
    29401 ccgtatttgt cgccggtggt tttgcgctgg tggcgtgggc gaccggcaac atgaactttg
    29461 ccagctattt acacataccg tatctacgac acgccgggga actggtcatt gtctgtaccg
    29521 cgatagtcgg ggcagggctg ggcttcctgt ggtttaacac ctatccggcg caggtcttta
    29581 tgggcgatgt aggttcgctg gcgttaggtg gtgcgttagg tattatcgcc gtactgctgc
    29641 gtcaggaatt cctgctggtg attatggggg gcgtgttcgt ggtagaaacg ctttccgtca
    29701 tcctgcaggt cggctccttt aaactgcgcg gacaacgtat tttccgcatg gcaccgattc
    29761 atcaccacta tgaactgaaa ggctggccgg aaccgcgcgt cattgtgcgt ttctggatta
    29821 tttcgctgat gctggtcctg attggtctgg caacgctgaa ggtacgttaa tcatggctga
    29881 ttaccagggt aaaaatgtcg tcattatcgg cctgggcctc accgggcttt cctgcgtgga
    29941 ctttttcctc gctcgcggtg tgacgccgcg cgttatggat acgcgtatga caccgcctgg
    30001 cctggataaa ttacccgaag ccgtagaacg ccacacgggc ggtctgaatg atgaatggct
    30061 gatggcggca gatctgattg tcgccagtcc cggtattgca ctggcgcatc catccttaag
    30121 cgctgccgct gatgccggaa tcgaaatcgt tggcgatatc gagctgttct gtcgtgaagc
    30181 acaagcaccg attgtggcga tcaccggttc taacggcaaa agcacggtca ccacgctagt
    30241 gggtgaaatg gcgaaagcgg cgggggttaa cgttggtgtg ggtggtaata ttggcctgcc
    30301 tgcgttgatg ctgttggatg atgagtgcga actgtacgtg ctggaactgt cgagtttcca
    30361 gctggaaacc acttccagct tacaagcggt ggcggcgacc attctgaacg tgactgaaga
    30421 tcatatggat cgctatccgt ttggtttaca acagtatcgt gcagcaaaac tgcgcattta
    30481 cgaaaacgca aaagtttgcg tggttaatgc tgatgatgcc ttaacaatgc cgattcgcgg
    30541 tgcggatgaa cgctgcgtca gctttggcgt caacatgggc gactatcacc tgaatcatca
    30601 gcagggcgaa acctggctgc gggtgaaagg cgagaaagtg ctgaacgtga aagaaatgaa
    30661 actttccggg cagcataact acaccaatgc gctggcggcg ctggcgctgg cagatgccgc
    30721 agggttaccg cgtgccagca gcctgaaagc gttaaccaca ttcactggtc tgccgcatcg
    30781 ctttgaagtt gtgctggagc ataacggtgt gcgctgggtt aacgattcaa aagcgaccaa
    30841 cgtcggcagt acggaagcgg cgctgaatgg cctgcatgta gacggcacgc tgcatttgtt
    30901 gctgggtggc gatggtaaat cggcggactt tagcccactg gcgcgttacc tgaatggcga
    30961 taatgtacgt ctgtattgtt tcggtcggga cggcgcgcag ctggcggcgc tacgcccgga
    31021 agtggcagaa caaaccgaaa ccatggaaca ggcgatgcgc ttgcttgctc cgcgtgttca
    31081 gccgggcgat atggttctgc tctccccggc ctgtgccagc cttgatcaat tcaagaactt
    31141 tgaacaacga ggcaatgagt ttgcccgtct ggcgaaggag ttaggttgat gcgtttatct
    31201 ctccctcgcc tgaaaatgcc gcgcctgcca ggattcagta ttctggtctg gatctccacg
    31261 gcgctaaagg gctgggtgat gggctcgcgg gaaaaagata ccgacagcct gatcatgtac
    31321 gatcgcacct tactgtggct gaccttcggc ctcgcggcga ttggctttat catggtgacc
    31381 tcggcgtcaa tgcccatagg gcaacgctta accaacgatc cgttcttctt cgcgaagcgt
    31441 gatggcgtct atctgatcct ggcattcatt ctggcgatca ttacgctgcg tctgccgatg
    31501 gagttctggc aacgctacag tgccacgatg ctgcttggat ctatcatcct gctgatgatc
    31561 gttctggtag tgggtagctc ggttaaaggg gcatcgcgtt ggatcgatct cggtttgctg
    31621 cgtatccagc ctgcggagct gacaaaactg tcgctgtttt gctatatcgc caactatctg
    31681 gtgcgtaaag gcgacgaagt acgtaataac ctgcgcggct ttctgaaacc gatgggcgta
    31741 attctggtgt tggctgtgtt actgctggca cagccagacc ttggtacggt ggtggtgttg
    31801 tttgtgacta cgctggcgat gttgttcctg gcgggagcga aattgtggca gttcattgcc
    31861 attatcggta tgggcatttc agcggttgtg ttgctgatcc tcgccgaacc gtaccgtatc
    31921 cgccgtgtta ccgcattctg gaatccgtgg gaagatccct ttggcagcgg ctatcagtta
    31981 acgcaatcgt tgatggcgtt tggtcgcggt gaactgtggg gacaaggttt aggtaactcg
    32041 gtacaaaaac tggagtatct gccggaagcg cacactgact ttattttcgc cattatcggc
    32101 gaagaactgg gatatgtcgg tgtggtgctg gcacttttaa tggtattctt cgtcgctttt
    32161 cgcgcgatgt cgattggccg caaagcatta gaaattgacc accgtttttc cggttttctc
    32221 gcctgttcta ttggtatctg gtttagtttt caggcgctgg ttaacgtagg cgcggcggcg
    32281 gggatgttac cgaccaaagg tctgacattg ccgctgatca gttacggtgg ttcgagctta
    32341 ctgattatgt cgacagccat catgatgctg ttgcgtattg attatgaaac gcgtctggag
    32401 aaagcgcagg cgtttgtacg aggttcacga tgagtggtca aggaaagcga ttaatggtga
    32461 tggcaggcgg aaccggtgga catgtattcc cggggctggc ggttgcgcac catctaatgg
    32521 ctcagggttg gcaagttcgc tggctgggga ctgccgaccg tatggaagcg gacttagtgc
    32581 caaaacatgg catcgaaatt gatttcattc gtatctctgg tctgcgtgga aaaggtataa
    32641 aagcactgat agctgcgccg ctgcgtatct tcaacgcctg gcgtcaggcg cgggcgatta
    32701 tgaaagcgta caaacctgac gtggtgctcg gtatgggcgg ctatgtatca ggtccaggtg
    32761 gtctggccgc gtggtcgtta ggcattccgg ttgtacttca tgaacaaaac ggtattgcgg
    32821 gcttaaccaa taaatggctg gcgaagattg ctaccaaagt gatgcaggcg tttccaggtg
    32881 ctttccctaa tgcggaagtg gtgggtaacc cggtgcgtac cgatgtgctg gcgctgccgt
    32941 tgccgcagca acgtttggct ggacgtgaag gtccggttcg tgtgttggta gtgggtggtt
    33001 cccagggcgc acgcattctt aatcagacaa tgccgcaggt tgctgcgaaa ctgggtgatt
    33061 cagtcactat ctggcatcag agcggcaaag gttcgcaaca atccgttgaa caggcgtatg
    33121 ccgaagtggg gcaaccgcag cataaagtga cggaatttat tgatgatatg gcggcggcgt
    33181 atgcgtgggc ggatgtcgtc gtttgccgct ccggtgcgtt aacggtgagt gaaatcgccg
    33241 cggcaggact accggcgttg tttgtgccgt ttcaacataa agaccgtcag caatactgga
    33301 atgcgctacc gctggaaaaa gcgggcgcag ccaaaattat cgagcagtca cagcttagcg
    33361 tggatgctgt cgcgaacacc ctggccgggt ggtcgcgaga aaccttatta accatggcag
    33421 aacgcgcccg cgctgcatcc attccggatg ccaccgagcg agtggcaaat gaagtgagcc
    33481 gggctgcccg ggcgtaattg tagcgatgcc ttttgcatcg tatgaattta agaagttaat
    33541 ggcgtaaaga atgaatacac aacaattggc aaaactgcgt tccatcgtgc ccgaaatgcg
    33601 tcgcgttcgg cacatacatt ttgtcggcat cggtggtgcc ggtatgggcg gtattgccga
    33661 agttctggcc aatgaaggtt atcagatcag tggttccgat ttagcgccaa atccggtcac
    33721 gcagcagtta atgaatctgg gagcgacgat ttatttcaac catcgcccgg aaaacgtacg
    33781 tgatgccagc gtggtcgttg tttccagcgc gatttctgcc gataacccgg aaattgtcgc
    33841 agctcatgaa gcgcgtattc cggtgatccg tcgtgccgaa atgctggctg agttaatgcg
    33901 ttttcgtcat ggcatcgcca ttgccggaac gcacggcaaa acgacaacca ccgcgatggt
    33961 ttccagcatc tacgcagaag cggggctcga cccaaccttc gttaacggcg ggctggtaaa
    34021 agcggcgggg gttcatgcgc gtttggggca tggtcggtac ctgattgccg aagcagatga
    34081 gagtgatgca tcgttcctgc atctgcaacc gatggtggcg attgtcacca atatcgaagc
    34141 cgaccacatg gatacctacc agggcgactt tgagaattta aaacagactt ttattaattt
    34201 tctgcacaac ctgccgtttt acggtcgcgc ggtgatgtgt gttgatgatc cggtgatccg
    34261 cgaattgtta ccgcgtgtgg ggcgtcagac cacgacttac ggcttcagcg aagatgccga
    34321 cgtgcgtgta gaagattatc agcagattgg cccgcagggg cactttacgc tgctgcgcca
    34381 ggacaaagag ccgatgcgcg tcaccctgaa tgcgccaggt cgtcataacg cgctgaacgc
    34441 cgcagctgcg gttgcggttg ctacggaaga gggaattgac gacgaggcta ttttgcgtgc
    34501 gctggagagc ttccagggga cggggcgccg tttcgatttc ctcggtgaat tcccgctgga
    34561 gccagtgaat ggtaaaagcg gtacggcaat gctggtcgat gactacggcc accacccgac
    34621 ggaagtggac gccactatta aagcggcgcg tgcaggctgg ccggataaaa acctggtaat
    34681 gctgtttcag ccgcaccgtt ttacccgtac gcgcgacctg tatgatgatt tcgccaatgt
    34741 gctgacgcag gttgataccc tgttgatgct ggaagtgtat ccggctggcg aagcgccaat
    34801 tccgggagcg gacagccgtt cgctgtgtcg cacaattcgt ggacgtggga aaattgatcc
    34861 cattctggtg ccggacccgg cgcaggtagc cgagatgctg gcaccggtat taaccggtaa
    34921 cgacctgatt ctcgttcagg gggctggtaa tatcggaaaa attgctcgtt ctttagctga
    34981 aatcaaactg aagccgcaaa ctccggagga agaacaacat gactgataaa atcgcggtcc
    35041 tgttgggcgg gacctccgct gagcgggaag tttctctgaa ttctggcgca gcggtgttag
    35101 ccgggctgcg tgaaggcggt attgacgcgt atcctgtcga cccgaaagaa gtcgacgtga
    35161 cgcaactgaa gtcgatgggt tttcagaaag tgtttatcgc gctacacggt cgcggcggtg
    35221 aagatggtac gctgcagggc atgctcgagc tgatgggctt gccttatacc ggcagcggag
    35281 tgatggcatc tgcgctttca atggataaac tacgcagcaa acttctgtgg cagagtgccg
    35341 gtttaccggt cgcgccgtgg gtagcattaa cccgcgcaga gtttgaaaaa ggccttaacg
    35401 ataagcagtt agcagaaatt tcttctctgg gtttgccggt aatcgttaag ccgagccgcg
    35461 aaggttccag tgtgggaatg tcaaaagtag tagcagaaaa tgctctacaa gatgcattaa
    35521 gattggcatt tcagcacgat gaagaagtat tgattgaaaa atggctaagt gggccggagt
    35581 tcacggttgc gatactcggt gaagaaattt taccgtcaat acgtattcaa ccggccggaa
    35641 ccttctatga ttatgaggcg aagtatctct ctgatgagac acagtatttc tgccccgcag
    35701 gtctggaagc gtcacaagag gccaatttgc aggcattagt gctaaaagca tggacgacgt
    35761 taggttgcaa aggatgggga cgtattgacg ttatgctgga cagcgatgga cagttttatc
    35821 tgctggaagc caatacctca ccgggtatga ccagccacag tctggtgccg atggcggcac
    35881 gtcaggcagg tatgagcttc tcgcagttgg tagtacgaat tctggaactg gcggactaat
    35941 atgtcgcagg ctgctctgaa cacgcgaaat agcgaagaag aggtttcttc tcgccgcaat
    36001 aatggaacgc gtctggcggg gatccttttc ctgctgaccg ttttaacgac agtgttggtg
    36061 agcggctggg tcgtgttggg ctggatggaa gatgcgcaac gcctgccgct ctcaaagctg
    36121 gtgttgaccg gtgaacgcca ttacacgcgt aatgacgata tccggcagtc gatcctggca
    36181 ttgggtgagc caggcacctt tatgacccag gatgtcaaca tcatccagac gcaaatagaa
    36241 caacgcctgc cgtggattaa gcaggtgagc gtcagaaagc agtggcctga tgaattgaag
    36301 attcatctgg ttgaatatgt gccgattgcg cggtggaatg atcaacatat ggtagacgcg
    36361 gaaggaaaca ccttcagcgt gccgccagat cgcaccagca agcaggtgct tccaatgctg
    36421 tatggcccgg aaggcagcgc caatgaagtg ttgcagggct atcgcgaaat ggggcagatg
    36481 ctggcaaagg acagatttac tctgaaggaa gcggcgatga ccgcgcgacg ttcctggcag
    36541 ttgacgctga ataacgatat taagctcaat cttggccggg gcgatacgat gaaacgtttg
    36601 gctcgctttg tagaacttta tccggtttta cagcagcagg cgcaaaccga tggcaaacgg
    36661 attagctacg ttgatttgcg ttatgactct ggagcggcag taggctgggc gcccttgccg
    36721 ccagaggaat ctactcagca acaaaatcag gcacaggcag aacaacaatg atcaaggcga
    36781 cggacagaaa actggtagta ggactggaga ttggtaccgc gaaggttgcc gctttagtag
    36841 gggaagttct gcccgacggt atggtcaata tcattggcgt gggtagttgc ccgtcgcgtg
    36901 gtatggataa aggcggggtg aacgacctcg aatccgtggt caagtgcgta caacgcgcca
    36961 ttgaccaggc agaattgatg gcagattgtc agatatcttc ggtatatctg gcgctttctg
    37021 gtaagcacat cagctgccag aatgaaattg gtatggtgcc tatttctgaa gaagaagtga
    37081 cgcaagaaga tgtggaaaac gtcgtccata ccgcgaaatc ggtgcgtgtg cgcgatgagc
    37141 atcgtgtgct gcatgtgatc ccgcaagagt atgcgattga ctatcaggaa gggatcaaga
    37201 atccggtagg actttcgggc gtgcggatgc aggcaaaagt gcacctgatc acatgtcaca
    37261 atgatatggc gaaaaacatc gtcaaagcgg ttgaacgttg tgggctgaaa gttgaccaac
    37321 tgatatttgc cggtctggca tcaagttatt cggtattgac ggaagatgaa cgtgaactgg
    37381 gtgtctgcgt cgtcgatatc ggtggtggta caatggatat cgccgtttat accggtgggg
    37441 cattgcgcca cacgaaggta attccttatg ctggcaatgt cgtgaccagt gatatcgctt
    37501 acgcctttgg cacaccgcca agtgacgccg aagcgattaa agttcgccac ggttgtgcgc
    37561 tgggctccat cgttggaaaa gatgagagcg tggaagtgcc gagcgtaggc ggtcgtccgc
    37621 cgcggagtct gcaacgtcag accctggcag aggtgatcga gccacgctat accgagctgc
    37681 tcaatctggt caacgaagag atattgcagt tgcaggaaaa gcttcgccaa caaggggtta
    37741 aacatcacct ggcggcaggc attgtattaa ccggtggcgc agcgcagatc gaaggtcttg
    37801 cagcctgtgc tcagcgcgtg tttcatacgc aagtgcgtat cggcgcgccg ctgaacatta
    37861 ccggtttaac ggattatgct caggagccgt attattcgac ggcggtggga ttgcttcact
    37921 atgggaaaga gtcacatctt aacggtgaag ctgaagtaga aaaacgtgtt acagcatcag
    37981 ttggctcgtg gatcaagcga ctcaatagtt ggctgcgaaa agagttttaa tttttatgag
    38041 gccgacgatg attacggcct caggcgacag gcacaaatcg gagagaaact atgtttgaac
    38101 caatggaact taccaatgac gcggtgatta aagtcatcgg cgtcggcggc ggcggcggta
    38161 atgctgttga acacatggtg cgtgagcgca ttgaaggtgt tgaattcttc gcggtaaata
    38221 ccgatgcaca agcgctgcgt aaaacagcgg ttggacagac gattcaaatc ggtagcggta
    38281 tcaccaaagg actgggcgct ggcgctaatc cagaagttgg ccgcaatgcg gctgatgagg
    38341 atcgcgatgc actgcgtgcg gcgctggaag gtgcagacat ggtctttatt gctgcgggta
    38401 tgggtggtgg caccggtaca ggtgcagcac cagtcgtcgc tgaagtggca aaagatttgg
    38461 gtatcctgac cgttgctgtc gtcactaagc ctttcaactt tgaaggcaag aagcgtatgg
    38521 cattcgcgga gcaggggatc actgaactgt ccaagcatgt ggactctctg atcactatcc
    38581 cgaacgacaa actgctgaaa gttctgggcc gtggtatctc cctgctggat gcgtttggcg
    38641 cagcgaacga tgtactgaaa ggcgctgtgc aaggtatcgc cgaactgatt actcgtccgg
    38701 gtttgatgaa cgtggacttt gcagacgtac gcaccgtaat gtctgaaatg ggctacgcaa
    38761 tgatgggttc tggtgtggcg agcggtgaag accgtgcgga agaagctgct gaaatggcta
    38821 tctcttctcc gctgctggaa gatatcgacc tgtctggcgc acgcggcgtg ctggtaaaca
    38881 tcacagcggg cttcgacctg cgtctggatg agttcgaaac ggtaggtaac accatccgtg
    38941 catttgcttc cgacaacgcg accgtggtta tcggtacttc tcttgacccg gatatgaatg
    39001 acgagctgcg cgtaactgtt gttgcgacag gtatcggcat ggacaaacgt cctgaaatca
    39061 ctctggtgac caataagcag gttcagcagc cagtgatgga tcgctaccag cagcacggta
    39121 tggctccgct gacccaggag cagaagccgg ttgctaaagt cgtgaatgac aatgcgccgc
    39181 aaactgcgaa agagccggat tatctggata tcccagcatt cctgcgtaag caagctgatt
    39241 aagaattgac tggaatttgg gtttcgaggc tctttgtgct aaactggccc gccgaatgta
    39301 tagtacactt cggttggata ggtaatttgg cgagataata cgatgatcaa acaaaggaca
    39361 cttaaacgta tcgttcaggc gacgggtgtc ggtttacata ccggcaagaa agtcaccctg
    39421 acgttacgcc ctgcgccggc caacaccggg gtcatctatc gtcgcaccga cttgaatcca
    39481 ccggtagatt tcccggccga tgccaaatct gtgcgtgata ccatgctctg tacgtgtctg
    39541 gtcaacgagc atgatgtacg gatttcaacc gtagagcacc tcaatgctgc tctcgcgggc
    39601 ttgggcatcg ataacattgt tatcgaagtt aacgcgccgg aaatcccgat catggacggc
    39661 agcgccgctc cgtttgtata cctgctgctt gacgccggta tcgacgagtt gaactgcgcc
    39721 aagaaatttg ttcgcattaa agagactgtt cgtgtcgaag atggcgataa gtgggctgaa
    39781 tttaaaccgt acaatggttt ttcgctggat ttcaccatcg attttaacca tccggctatt
    39841 gattccagca accagcgcta tgcgatgaac ttctccgctg atgcgtttat gcgccagatc
    39901 agccgtgcgc gtacgttcgg tttcatgcgt gatatcgaat atctgcagtc ccgtggtttg
    39961 tgcctgggcg gcagcttcga ttgtgccatc gttgttgacg attatcgcgt actgaacgaa
    40021 gacggcctgc gttttgaaga cgaatttgtg cgtcacaaaa tgctcgatgc gatcggtgac
    40081 ttgttcatgt gtggtcacaa tattattggt gcatttaccg cttataaatc cggtcatgca
    40141 ctgaataaca aactgctgca ggctgtcctg gcgaaacagg aagcctggga atatgtgacc
    40201 ttccaggacg acgcagaact gccgttggcc ttcaaagcgc cttcagccgt actggcataa
    40261 cgacatttat actgtcgtat aaaattcgac tggcaaatct ggcactctct ccggccaggt
    40321 gaaccagtcg ttttttttga attttataag agctataaaa aacggtgcga acgctgtttt
    40381 cttaagcact tttacgcaca acttatcttc attcgtgctg tggacttcag gctttaatga
    40441 taagatttgt gcgctaaata cgtttgaata cgatcgggat ggcaataacg tgagtggaat
    40501 actgacgcgc tggcgacagt ttggtaaacg ctacttctgg ccgcatctct tattagggat
    40561 ggtcgcggcg agtttaggtt tgcctgcact cagcaatgcc gccgaaccaa acgcgcccgc
    40621 aaaagcgaca acccgcaacc acgagccttc agccaaagtt aactttggtc aattggcctt
    40681 gctggaaacg aacacgcgcc gcccgaattc gaactattcc gttgattact ggcatcaaca
    40741 tgccattcgc acggtaatcc gccatctttc ctttgcaatg gcaccgcaaa cgctgcccgt
    40801 tgctgaagaa tctttgcctc ttcaggcgca acatcttgca ttactggata cgctcagcgc
    40861 gctgctgacc caggaaggca cgccgtctga aaagggttat cgcattgatt atgcgcattt
    40921 taccccacaa gcaaaattca gcacgcccgt ctggataagc caggcgcaag gcatccgtgc
    40981 tggccctcaa cgcctcagct aacaacaata aacctttact tcattttatt aactccgcaa
    41041 cgcggggcgt ttgagatttt attatgctaa tcaaattatt aactaaagtt ttcggtagtc
    41101 gtaacgatcg caccctgcgc cggatgcgca aagtggtcaa catcatcaat gccatggaac
    41161 cggagattga aaaactctcc gacgaagaac tgaaaggaaa aacggcagag ttccgcgcgc
    41221 gtctggaaaa aggcgaagtg ctggaaaact tgatcccgga agccttcgcc gtggtgcgtg
    41281 aagccagtaa gcgtgttttt ggcatgcgcc acttcgacgt acagctgctc ggcggtatgg
    41341 ttcttaatga acgctgcatc gcggaaatgc gtaccggtga aggtaaaacc ctgaccgcaa
    41401 cgctgcctgc ttacctgaac gcactaaccg gtaaaggcgt gcacgtcgtt accgtcaacg
    41461 actacctggc gcaacgtgac gccgaaaaca accgtccgct gtttgaattc cttggcctga
    41521 ctgtcggtat caacctgccg ggcatgccag caccggcaaa gcgtgaagcc tacgctgctg
    41581 acatcactta cggtacgaac aacgaatacg gctttgacta cctgcgtgac aacatggcgt
    41641 tcagtcctga agaacgtgta cagcgtaaac tgcactatgc gctggtggac gaagtggact
    41701 ccatcctgat cgatgaagcg cgtacaccgc tgatcatttc tggcccggca gaagacagct
    41761 cggaaatgta taaacgcgtg aataaaatta ttccgcacct gatccgtcag gaaaaagaag
    41821 actccgaaac cttccagggc gaaggccact tctcggtgga cgaaaaatct cgccaggtga
    41881 acctgaccga acgtggtctg gtgctgattg aagaactgct ggtgaaagaa ggcatcatgg
    41941 atgaagggga gtctctgtac tctccggcca acatcatgct gatgcaccac gtaacggcgg
    42001 cgctgcgcgc tcatgcgctg tttacccgtg acgtcgacta catcgttaaa gatggtgaag
    42061 ttatcatcgt tgacgaacac actggtcgta ccatgcaggg gcgtcgctgg tctgatggtc
    42121 tgcaccaggc tgtggaagcg aaagaaggtg tgcagatcca gaacgaaaac caaacgctgg
    42181 cttcgatcac cttccagaac tacttccgtc tgtatgaaaa actggcgggg atgactggta
    42241 ctgctgatac cgaagctttc gaattcagct ccatctataa gctggatact gtcgttgttc
    42301 cgaccaaccg tccaatgatt cgtaaagatc tgccggacct ggtctacatg actgaagcgg
    42361 aaaaaattca ggcgatcatt gaagatatca aagaacgtac tgcgaaaggc cagccggtgc
    42421 tggtgggtac aatctccatc gaaaaatcgg agctggtgtc aaatgaactg accaaagccg
    42481 gtattaagca caacgtcctg aacgccaaat tccatgccaa cgaagcggcg attgttgctc
    42541 aggcaggtta tccggctgcg gtgactatcg cgaccaacat ggcgggtcgt ggtaccgata
    42601 ttgtgctcgg tggtagctgg caggcagaag ttgccgcgct ggaaaatccg actgcagagc
    42661 aaattgaaaa aattaaagcc gactggcagg tacgtcacga tgcggtactg gcagcaggtg
    42721 gcctgcatat catcggtact gaacgtcacg aatcccgtcg tatcgataac cagctgcgcg
    42781 gtcgttctgg tcgtcagggg gatgctggtt cttcccgttt ctatctgtcg atggaagatg
    42841 cgctgatgcg tatttttgcc tccgaccgag tatccggcat gatgcgtaaa ctaggtatga
    42901 agccaggcga agccattgag cacccgtggg tgaccaaagc gattgccaac gcccagcgta
    42961 aagttgaaag ccgtaacttc gacattcgta agcaactgct ggaatatgat gacgtggcta
    43021 acgatcagcg tcgcgccatt tactcccagc gtaacgaact gctggatgtc agcgatgtga
    43081 gcgaaaccat caacagcatt cgtgaagatg tgttcaaagc gaccattgat gcctacattc
    43141 cgccacagtc gctggaagaa atgtgggata ttccggggct gcaggaacgt ctgaagaacg
    43201 atttcgacct cgatttgcca attgccgagt ggctggataa agaaccagaa ctgcatgaag
    43261 agacgctgcg tgagcgcatt ctggcgcagt ccatcgaagt gtatcagcgt aaagaagaag
    43321 tggttggtgc tgagatgatg cgtcacttcg agaaaggcgt catgctgcaa acgcttgact
    43381 ctctgtggaa agagcacctg gctgcgatgg actatctgcg tcagggtatc cacctgcgtg
    43441 gctatgcaca gaaagatccg aagcaggaat acaaacgtga atcgttctcc atgtttgcag
    43501 cgatgctgga gtcgttaaaa tatgaagtta tcagcacgct gagcaaagtt caggtgcgta
    43561 tgcctgaaga ggttgaggag ctggaacaac agcgtcgtat ggaagccgag cgtttagcgc
    43621 aaatgcagca gcttagccat caggatgacg actctgcagc cgcagctgca ctggcggcgc
    43681 aaaccggtga acgaaaagta ggacgtaacg atccttgccc gtgtggttct ggtaaaaaat
    43741 acaagcagtg ccatggccgc ctgcaataaa agctaactgt tgaagtaaaa ggcgcaggat
    43801 tctgcgcctt ttttataggt ttaagacaat gaaaaagctg caaattgcgg taggtattat
    43861 tcgcaacgag aacaatgaaa tctttataac gcgtcgcgca gcagatgcgc acatggcgaa
    43921 taaactggag ttttccggcg gtaaaattga aatgggcgaa acgccggaac aggcagtggt
    43981 acgtgaactt caggaagaag tcgggattac cccacaacat ttttcgctat ttgaaaaact
    44041 ggaatatgaa ttcccggaca ggcatataac tctgtggttc tggctggtcg aaagctggga
    44101 aggggagccg tggggtaaag aagggcaacc cggtgagtgg atgtcgctgg tcggtcttaa
    44161 tgccgatgat tttccgccag ccaatgaacc ggtaattgcg aaacttaagc gtgtgtatgt
    44221 cgaataaggc gtcacgctgc atccgacatt tgcatatgat gcctgatgcg acgctggcgc
    44281 gttttatcag gccagcatcg catcagatag aatgtcactg ctttggctct tcgctccagt
    44341 catcgctttc ggaaagatcg ccactgctgg ggattcgttt ttcttcagca gcccattctc
    44401 cgaggtcgat cagctgacaa cgtttggagc aaaatggccg aaacgggctg atttcacccc
    44461 acaccaccgt tttcccgcag gttgggcaat tcaccgtaat agtttctgac atttttactc
    44521 cttagcaaca ggccagttcg aaatccagac gttctggtac ttgtccgttt tcactgtcca
    44581 gcggcataaa acgaatggca aaacggctct tatgaccgga aatttgcgga taaagctgtg
    44641 aatcgagcga cagattcagg cgcagcaagt cggcatcgcc accgttatcc tgataaaaac
    44701 cattcaggct ggtttgttta cggaaggggg ccgactggcg aattaaatcc agcaccatgg
    44761 taagtgcctg ggtaagtggg ttcaggctgg caatccaggt ttctacctgg ctgtcgcgct
    44821 gcgcctgggg tagatgcagc caaatgtgca atgtaggtaa atcaaagctg caacagccgc
    44881 ccgggatgct cagtcgctga cgcaccagag caatcaaacg atcttcacgt agaaattgcc
    44941 cgatacgcgg cgcggaaatt aatacgctcc ccgccgcttt taactgctga attaatgctt
    45001 caatacggct ctggtccacg ccgggcacgc caatccaggt ctggagttta cgttgctgcc
    45061 ggtcaagttc tttcaacagc tcagtgcgga cttcgccgcg ctcgaaaaca tccagtaatt
    45121 cgctgacatt acggaagaaa tgcagcgcgc cagcgtggtc aacgatgggt aaattaacgg
    45181 tgagttgctg aatcaaaaac tcaatgcgca gccatgtacg cattttttca tttagtggat
    45241 gttcaaaaag gacctgggtc tgcattacgg tttttcctgt gagacaaact gcgacgcaag
    45301 ctgcaaatag tgtgcgtgca ggcgggcaac atccgatgcg atagcatccg gtgcgccgtt
    45361 attatcaatg acgtcatctg ccacggcaag gcgagcttcg cgcgttgcct gagcagcaag
    45421 gatttgttcg acatgctcgc gagttacatc gtcgcgctgc atggtgcgct taagttgcgt
    45481 ttctgggctg acatccacca ccagcactcg attcgctttt ttatacagtg agttttctac
    45541 cagcaatggc acaacccata gtacataggg ggaagtagct tgctggatct ggtgttgcgt
    45601 ctcttgctga atcagcggat gcagcagggc gttaagccag tttttctctt ccgggttggc
    45661 gaagatccgc tcgcgcaagg cccggcgctg caatgttcca tcagcagcaa tcatgttagc
    45721 gccaaagtga tcagcaatgg catgtagcgc aggtgcacct ggttcaacca cctgacgcgc
    45781 aataatatcg gcatcaatga cgttaattcc gagatcagca aacgcattgg caacggtact
    45841 cttgccactg ccaatgcctc ccgttaaggc aactatatac ctcataattt atattcccgg
    45901 gaattcatca tgattatcaa aacgttaaaa atgagcgcac gaaagcgaaa ttgatgaaac
    45961 gttcgctcac tatttaccag gtaaatttat gggattgtag cgtaaaaaaa gacaatttcg
    46021 cagtcttgcg ccgcattgat tagtgcgtat gataacgtca ctggagttgc gctcttaccc
    46081 ttatagccat taaccccagg aatccgcaca tgcgtattga agaagatctg aagttaggtt
    46141 ttaaagacgt tctcatccgc cctaaacgct ccactcttaa aagccgttcc gatgttgaac
    46201 tggaacgtca attcaccttc aaacattcag gtcagcgctg gtccggcgtg ccaattatcg
    46261 ccgccaatat ggacaccgta ggcacatttt ctatggcctc tgcgctggct tcttttgata
    46321 ttttgactgc tgtgcataaa cactattctg tcgaagagtg gcaagcgttt atcaacaatt
    46381 cttccgctga tgtgctgaaa catgtgatgg tttctaccgg cacgtctgat gcggatttcg
    46441 aaaaaactaa acagattctc gacctgaacc cggcattaaa cttcgtttgt attgacgtgg
    46501 cgaatggtta ttccgaacac ttcgtgcagt tcgttgcgaa agcgcgtgaa gcgtggccga
    46561 ccaaaaccat ttgtgctggc aacgtagtga ctggtgaaat gtgtgaggag cttatcctct
    46621 ccggtgctga tatcgttaaa gttggcattg gcccaggttc tgtttgtaca actcgcgtca
    46681 aaacaggcgt cggttatccg caactttctg cggtgatcga atgtgccgat gctgcgcatg
    46741 gtctgggcgg aatgatcgtc agcgacggtg gctgcaccac gccgggcgat gtcgcgaaag
    46801 cctttggcgg cggtgccgat ttcgtcatgc ttggcggcat gctggcgggc cacgaagaga
    46861 gcggcggtcg catcgttgag gagaacggcg agaaatttat gctgttctac ggcatgagct
    46921 cagagtctgc gatgaaacgt cacgttggcg gtgttgcgga atatcgcgca gcagaaggta
    46981 aaaccgttaa gctgccgctg cgaggcccgg ttgaaaatac cgcgcgtgat attttgggcg
    47041 gcctgcgttc agcttgtaca tacgttgggg cttcacgcct gaaagaactg accaagcgca
    47101 ccacatttat ccgtgtgcag gaacaagaaa accgcatctt caacaacctg taatatacca
    47161 acgctggcgt ggagcaacac gccagcgtta tcccattcca ctcatcgcat cgcctaaatg
    47221 gaaaattggc agatacattg ccaccaccag cgtaccgata attcctcccg ttatgatcag
    47281 caacgccggt tccagtaagg ctgcgaggtt atccgccagc gccattgtgt tatcccgatg
    47341 atgatgggcg aggttgtcta acatgagatc cagcgagccg gatgcctctc ctgttctcac
    47401 taattgcaaa cagagcgggc taaactcacc ggcatttttt agcgccagcc agatggggtg
    47461 accgttactg atatcgtgct ggatttgtgt cagaagttgc acccagtacg gacagcgcat
    47521 tgtttctctg acgctctcaa cgccctgtaa aaaagaaatg cctgcacttt gtgtcagcgt
    47581 cagaatcgta aagatctgcg tgagtttttg tccccgcatc agtgaaccca taatcgggat
    47641 gcgtaacagt aatttctgcc gtgcgataag cctggttggg tggcgcatca gcagcttatt
    47701 ggctatcgcc agcagaaagc cgaatagcac cagcaaccaa ccccattcgc cactaaaact
    47761 tgccagcgtc atgatcccct gcgttagcgc cggtagcgga gtgttaaagg tcttatagat
    47821 agcggcaaac tccggcagaa caaaatgcag cattgccaca accaccatga ttgccatcgc
    47881 taaaatgata atgggataac gtaacgctga tttcactttg tcggtcaact gacgctgggc
    47941 tttttgctga cgcgccagtt caaagcagca ttcatccagc ttaccggtca gttcacctgt
    48001 gcggatcatc gcctgataga gcggcggaaa tacctctgac cagggtaata aggcattgga
    48061 aaaggcaacg ccctgttcaa gatcgtgcgc cagtgattgc agcaacgctt gccactgctt
    48121 actgggatgc tgttccgcca gcagagccag cccttcagaa agcgttaacc cggctttgag
    48181 tagcgtcgcc agttgatgaa tgacttccgc gcttttatct cctcgccact gcgcagaatt
    48241 gatggcgatt cgcttcaggc ttagtggggt aaccatctgt tgctgtagtg ccatgagcag
    48301 caaagcacgg ctctctgccc atagcatccc atcttgcgca ttgccgtcgc cggttatgcc
    48361 acgccagcgc cagagttgct tactcgccat gcggcatccc caatacgcgg attaactctt
    48421 caaaggtggt taagccttgc tccacagcca ggcagccgtt ttcaaaaagc gttcgcatac
    48481 ccgcctgtcg ggcgtgcgtt tccagcgatt caacgtcggt attagcggaa ataagctgac
    48541 gtatgaccgg tgttatgggc agaacttcaa ataaggccgt gcgaccataa aaaccgtggt
    48601 agcaatgtac acaaccgggt gcctgtcagt ggggcagcgg cgacggccat acattgtctg
    48661 gaatatggat gggctcccct tgctgccggc gacaatgcgg gcaaagtttg cgtaccagac
    48721 gctgggctat taccagcgta agcgccgatg atagcatcca gcgggcgact cccatttgct
    48781 gtaaacgtac cagcgtttcg caggtggaat tagtgtgtag ggtagacaac accaggtgac
    48841 cggtttgcgc ggcttttatg gcaatttctg ccgtttcgcc atcgcggatc tctccgatca
    48901 tgatgacgtc aggatcctgg cgcaataacg cacgcaaaac gccctgaaag gtgagtccgg
    48961 cacgcgaatg gatttgcgtc tggtttaatc cggctatggg gatctcaacc ggatcttcga
    49021 cgctacaaat attaatgtca gcggtattca gcgtttgcag ggcactataa agcgtgaccg
    49081 ttttgccgct gcctgtaggg ccagttacca gcaccagtcc ctgtggttgt tgcaaggcat
    49141 gagcaaagtc caccagttgt gacggctgca ttccaagcgt gttaacatcc agtgcctggt
    49201 tcacctgctg taacaacctt aataccacct tttcaccacc ccgacatgct aaggtcgcaa
    49261 tacgaaatga gacggcgttt cctgccagtt cgacagtgaa ttgcccgtcc tgcggcaggc
    49321 gatgttccgc aatatccagg tttcccagca cttttaatct ggcggttaat gcgactccgg
    49381 catccggtga aacgtccggt aaaggatgca atacgccgtc gatacgcaag cggatgcggt
    49441 aggcattgtc cgctggttcg atatgaatat cagacgcgcg ttgttctagc gcagattgta
    49501 acgttcgagt cagcaactct gctttgggct gatgcttctc ctgaacagct acgggcaatg
    49561 tctgttgtgt gcgactggcg tgaccttcca tttgttggcg cgtccagcag gtgatctcaa
    49621 tacgtttggt ggtagcgaaa tgcaatgcgt ccagtagctc atgcgaaggt gcatcgacta
    49681 ccgcaacatg aaccacctct tcgctggcat ccagcaagac tccctgataa cgcagacaca
    49741 gggcagtgag ctgtggaata ttcattgccg ctccttagtt ggcgtcatca aagcggaaga
    49801 catcttcgca ggcttgctgc aatgcgctgt cactttgaat attgcagtta cgcgtccagc
    49861 cggtgacgcc gtttgcgtta tcccaacccg gtgtcatgac gacgcttagc ccattgagac
    49921 tttcttgccc ggtcagcgac accacgccct ttgccacact catggctgaa acatagcggg
    49981 tggtggtagg cgaaggaatg ccattgctgc caccgtcgca ggtatttaat ccaccatgtt
    50041 ccagcgcgca caactctacg gcggtacggt aaggcacaaa ggtttgtagc atgtcggtga
    50101 gtgcggcttt gcgcaggtag ttttgataag cgggaatacc aatggcgctt aaaatggcaa
    50161 tgatgccaat aaccaccatc agttcaataa gtgtaaaacc gcgttgcttg tccatctgtt
    50221 tcgctccttg atttggttgg cgctactttg gcaaacgcca tcagcacaag cgaggggcaa
    50281 aaaacgaaac gggaaagcag cttccgaggt tttttacttc gttgcagcga aagacaagaa
    50341 atttgcgagg cgttacgaag aaagttgggg aaggggagat ttatccgccc gcgatggagc
    50401 ggataaatct gttagcaatt agcgaaaacg cattgaaagg tcgagtgcct gtacgtgttt
    50461 agttagtgca ccaacggaga taaagtccac gcccgtttcg gcaaattcgc gcagtgtttt
    50521 gtcagtgacg ttgccagaca cttccagtag cgccttgccg ttggtgcgtt tgacggcttc
    50581 gcgcatctgt tctgtttcga agttatccag catgatgata tcggcacctg ctttcagggc
    50641 ttcatcaagt tcttccagat tctctacttc gacttctact ggcgcatccg ggtgcaacca
    50701 ggacgctttt tcgaccgcct gccgcactga gccggaggca ataatatggt tttctttgat
    50761 caggaaggca tcagaaagcc ccagacggtg attcgctccg ccgccgcaaa gtaccgcgta
    50821 tttcagagct gaacgcaggc cgggtaaggt tttgcgcgta tccaacagct gcgtgttggt
    50881 gccttccagt aattcgacat agtggcgtac cttactggca actcctgaaa gggtttgcac
    50941 aaaattaagc gcagtgcgtt cgcccgttaa cagcacgcga gatgggcctt caagttcgaa
    51001 caagggttga ttggcgttga tgacatcgcc gtcatccaca tgccagatta tggtgacatc
    51061 gtcgcctgcc agttgaataa acacctcttc aacccagcgt ttgccgcaaa atacgccatt
    51121 ctcgcgggtg atcactgtgg catgagagcg agagttttcc ggtaaaagtt ttgccgtaat
    51181 gtcattgttg gcatcgactg ttccgcctaa atcttcccgc agcgcctggg ccaccgcgcc
    51241 ggggatatcg agattaatgc gttccagcag ctcgtcacgt cgggtgtcag ggttatagcg
    51301 gcgaggcggc atgttaaaac tccagatagc taacgaatca taaggtagaa acatgctact
    51361 ctgaaccggg tattagcacc acatataagg agatcctgca tgttgttaga acaggggtgg
    51421 ctggctggcg cgcgccgcgt tccctcacca cattacgatt gccgcccgga tgacgaaaca
    51481 cccaccctgc tggtggtgca caatattagc ctgccgccag gcgagtttgg cggtccgtgg
    51541 atcgacgcat tattcactgg aactattgat ccgcaggcgc atcctttctt tgcggagatc
    51601 gcccatttgc gcgtctccgc tcactgtttg attcgccgtg atggtgaaat agtccagtat
    51661 gttcctttcg ataaacgagc ctggcatgcg ggagtctctc agtatcaggg gcgcgaacgc
    51721 tgcaatgatt tttctattgg gattgagctg gaaggcaccg atacgctggc gtataccgat
    51781 gcgcagtatc aacagcttgc ggcggttaca cgggcactga ttgatcgcta tccggatatc
    51841 gctaataaca tgacgggcca ttgtgatatt gcgccggatc ggaaaaccga tcccggtcct
    51901 gcatttgatt gggcacggtt tcgtgcgctg gtcagcaagg agacaacatg acgctattta
    51961 caaccttact ggtgttaatt ttcgagcgcc tgtttaagtt gggcgagcac tggcagcttg
    52021 atcatcgtct tgaagcgttc tttcggcggg tgaaacattt ttctctcggg cgcacgttat
    52081 gcatgaccat tattgcgatg ggcgtgactt ttttactgtt acgcgcattg cagggtgtat
    52141 tgttcaacgt tcccacgttg ctggtgtggc tgctgattgg tttgctgtgt attggcgcag
    52201 gtaaagttcg tcttcattat catgcttatc tgacagctgc ttcacgtaat gatagccatg
    52261 cccatgccac gatggctggc gaactcacca tgattcacgg cgtcccggca ggctgcgatg
    52321 aacgtgagta tttgcgtgag ctgcaaaatg cattgctgtg gattaacttt cgtttttatc
    52381 ttgctccgct gttctggctg attgtggggg gaacctgggg acccgttacg ctgatggggt
    52441 atgcgttttt gcgtgcatgg caatactggc tggcgcgata ccagacgccg catcatcgtt
    52501 tacagtccgg cattgatgcc gtgcttcatg cactggattg ggtgccggtt cgtcttgcgg
    52561 gtgtggtata tgccttgatc ggtcatggtg agaaagcgtt accggcctgg tttgcttcgc
    52621 tgggtgattt ccatacttcg caatatcagg tattaacgcg tctggcacag ttctctctgg
    52681 cgcgtgaacc gcatgtcgat aaggtggaga cgccaaaggc cgcggtttca atggcgaaga
    52741 aaacctcgtt cgtggtcgtg gtggtaattg cgctactgac gatttacggg gcgttggtgt
    52801 aaagattatt gccctcaccc tgcacgggtg agggcgtaga gagattaatg cgcttttacg
    52861 gctttggcgg ttttctcttt aaacagatag ccgataccta acacgatcag ccataccggg
    52921 atcaggtata ccgaaatcgc cattcctggg gtcatcagca taatcaccag taccgccgcc
    52981 ataaacagca ggcagatcca gttacccagc ggataaagca gggcagggaa gcgagttacc
    53041 acgccttgtt cttgtttggc acgacggaat ttcatatgcg ccagactgat catcgcccag
    53101 ttgatgacca gtgcagatac caccagcgcc attaacagtc cgaaagcgga ctctggggca
    53161 aggtagttaa tcagtacgca caatgccgta accagcgcag acaccagaat agtgttaacc
    53221 ggtacgccgc gtttatcgac agacgccagc gcttttggcg cgttcccttg ttgtgccaga
    53281 ccgaacagca tacggctgtt gcaatatacg cagctgttgt acacggagag cgcagcagtc
    53341 agtaccacga tattcagcgc attcgctaca aaggtatcgc ctaactcgtg gaagatcagc
    53401 acaaacggac tggtatcggc ggtaacgcgg gtccacggca ttagtgagag cagaacggct
    53461 aacgagccaa tatagaaaat caggatgcgg tagataacct ggttagttgc tttcgggata
    53521 ctttgctccg ggttatcagc ttctgctgcg gtgatcccca ccagttccag accaccgaaa
    53581 gagaacatga taatcgccat catcatcacc agaccggtga agccgtgtgg caggaaacca
    53641 ccctgatccc acaggttgct aacgctcgcc tgcgggccgc cgttgccgct gaatagcagc
    53701 caggcgccga agatgatcat cgctaccacc gcgataactt tgataatggc aaaccagaac
    53761 tccatctcgc caaacacttt tacgtttgtc aggttgatgg cgttgatcac cacaaagaac
    53821 acggcggcag aaacccaggt tgggatttcc ggataccaga actgaatgta tttacccacg
    53881 gcagtcagct ctgccatggc aactaaaacg tacagtaccc agtagttcca gccagaggcg
    53941 aaaccggcaa aactgcccca gtatttataa gcaaagtggc taaaggagcc tgcgacaggt
    54001 tcttcgacca ccatttcacc tagctgacgc atgatcagaa aggcgataaa accagcaatg
    54061 gcgtaaccca ggataatccc tggccctgcg gactgtatta cggaggcgct acccaggaat
    54121 agccctgtcc ctatcgcgcc acccagcgcg ataagctgaa tatggcggtt tttaaggccg
    54181 cgctttagct gctcgccgtg ctgttgacct tccattatga aacctcgtgt tgtgttgttt
    54241 ttttgaacta cgcagcaatg cgtgtgtaat tttgtaattc cgtttgttgt attggtttct
    54301 ttacatttta tgtaactgaa ttatgatgat agtactttca actatcacaa gataatggta
    54361 tacgcgcgag aatgcacctg ctttatgtag atgtgttgat tttctggata aaaaaaaagc
    54421 aattgtaagt ttttcatcac atttaataga tactttaagt ctgataacat actgttttaa
    54481 ctagctatat accggatttg tctgcctgct gaacaccatg ccttagccac cagcacaata
    54541 atcttacaaa aggtcatata agaataaata gatgttaata atacaatggg tttgtaacgc
    54601 gagtatttaa
//
LOCUS       DAPOXO010000026        53027 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPOXO010000026 DAPOXO010000000
VERSION     DAPOXO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 53027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53027
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.026"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(142..2478)
                     /gene="arcB"
                     /locus_tag="ROH59_001893"
     CDS             complement(142..2478)
                     /gene="arcB"
                     /locus_tag="ROH59_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HDX4804376.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFERMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(2574..3503)
                     /locus_tag="ROH59_001894"
     CDS             complement(2574..3503)
                     /locus_tag="ROH59_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562163.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDX4804377.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARERGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALGRPWLPPTA"
     gene            4178..8638
                     /gene="gltB"
                     /locus_tag="ROH59_001895"
     CDS             4178..8638
                     /gene="gltB"
                     /locus_tag="ROH59_001895"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HDX4804378.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEDHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVEQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHPGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDDLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            8651..10069
                     /gene="gltD"
                     /locus_tag="ROH59_001896"
     CDS             8651..10069
                     /gene="gltD"
                     /locus_tag="ROH59_001896"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HDX4804379.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVKAIVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
     gene            complement(10137..10601)
                     /locus_tag="ROH59_001897"
     CDS             complement(10137..10601)
                     /locus_tag="ROH59_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDX4804380.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSAIENEQAIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(10598..11473)
                     /gene="nanK"
                     /locus_tag="ROH59_001898"
     CDS             complement(10598..11473)
                     /gene="nanK"
                     /locus_tag="ROH59_001898"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HDX4804381.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPQALRDA
                     LSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIA
                     INDAQAAAWAEYQALDGDITDMVFITVSTGVGGGVVSGGKLRTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGANAKTIFTRAGQGDEQAQQLIHRSA
                     RTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEIL"
     gene            complement(11470..12159)
                     /locus_tag="ROH59_001899"
     CDS             complement(11470..12159)
                     /locus_tag="ROH59_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDX4804382.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            complement(12207..13697)
                     /gene="nanT"
                     /locus_tag="ROH59_001900"
     CDS             complement(12207..13697)
                     /gene="nanT"
                     /locus_tag="ROH59_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HDX4804383.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYDPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGISGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALGSLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS"
     gene            complement(13806..14699)
                     /gene="nanA"
                     /locus_tag="ROH59_001901"
     CDS             complement(13806..14699)
                     /gene="nanA"
                     /locus_tag="ROH59_001901"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDX4804384.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            complement(14821..15612)
                     /gene="nanR"
                     /locus_tag="ROH59_001902"
     CDS             complement(14821..15612)
                     /gene="nanR"
                     /locus_tag="ROH59_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417693.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HDX4804385.1"
                     /translation="MSPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
     gene            complement(15720..16217)
                     /gene="sspB"
                     /locus_tag="ROH59_001903"
     CDS             complement(15720..16217)
                     /gene="sspB"
                     /locus_tag="ROH59_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HDX4804386.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDASIMNDEEASADNETVMSVIDGDKPDHDDETHPDDEPPQPPRGGRPA
                     LRVVK"
     gene            complement(16223..16861)
                     /gene="sspA"
                     /locus_tag="ROH59_001904"
     CDS             complement(16223..16861)
                     /gene="sspA"
                     /locus_tag="ROH59_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HDX4804387.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            complement(17256..17648)
                     /gene="rpsI"
                     /locus_tag="ROH59_001905"
     CDS             complement(17256..17648)
                     /gene="rpsI"
                     /locus_tag="ROH59_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDX4804388.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(17664..18092)
                     /gene="rplM"
                     /locus_tag="ROH59_001906"
     CDS             complement(17664..18092)
                     /gene="rplM"
                     /locus_tag="ROH59_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDX4804389.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            complement(18312..19439)
                     /gene="zapE"
                     /locus_tag="ROH59_001907"
     CDS             complement(18312..19439)
                     /gene="zapE"
                     /locus_tag="ROH59_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HDX4804390.1"
                     /translation="MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYKELVNSTP
                     PAPRTSGLMARVGKLWGKREDTKHMPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLNDETRAQMDKLWLALAGAKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYEIYQGERLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            19633..20031
                     /locus_tag="ROH59_001908"
     CDS             19633..20031
                     /locus_tag="ROH59_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HDX4804391.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            20185..21552
                     /gene="degQ"
                     /locus_tag="ROH59_001909"
     CDS             20185..21552
                     /gene="degQ"
                     /locus_tag="ROH59_001909"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HDX4804392.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIIRGNESL
                     YLLMR"
     gene            21642..22709
                     /gene="degS"
                     /locus_tag="ROH59_001910"
     CDS             21642..22709
                     /gene="degS"
                     /locus_tag="ROH59_001910"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HDX4804393.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINPRRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQSGGM
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVNNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(22772..23710)
                     /gene="mdh"
                     /locus_tag="ROH59_001911"
     CDS             complement(22772..23710)
                     /gene="mdh"
                     /locus_tag="ROH59_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDX4804394.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK"
     gene            24145..24615
                     /gene="argR"
                     /locus_tag="ROH59_001912"
     CDS             24145..24615
                     /gene="argR"
                     /locus_tag="ROH59_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HDX4804395.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKELYEAILELFDQEL"
     gene            24979..25242
                     /gene="yhcN"
                     /locus_tag="ROH59_001913"
     CDS             24979..25242
                     /gene="yhcN"
                     /locus_tag="ROH59_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HDX4804396.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
     gene            complement(25297..25569)
                     /locus_tag="ROH59_001914"
     CDS             complement(25297..25569)
                     /locus_tag="ROH59_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HDX4804397.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(25661..27628)
                     /gene="aaeB"
                     /locus_tag="ROH59_001915"
     CDS             complement(25661..27628)
                     /gene="aaeB"
                     /locus_tag="ROH59_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HDX4804398.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPCMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVHRLTGMLHKYQHALTDS"
     gene            complement(27634..28566)
                     /gene="aaeA"
                     /locus_tag="ROH59_001916"
     CDS             complement(27634..28566)
                     /gene="aaeA"
                     /locus_tag="ROH59_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HDX4804399.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            complement(28574..28777)
                     /locus_tag="ROH59_001917"
     CDS             complement(28574..28777)
                     /locus_tag="ROH59_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HDX4804400.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            28960..29889
                     /gene="aaeR"
                     /locus_tag="ROH59_001918"
     CDS             28960..29889
                     /gene="aaeR"
                     /locus_tag="ROH59_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HDX4804401.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            complement(30011..31456)
                     /gene="tldD"
                     /locus_tag="ROH59_001919"
     CDS             complement(30011..31456)
                     /gene="tldD"
                     /locus_tag="ROH59_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HDX4804402.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVNNLTVGGTA"
     gene            complement(31612..35412)
                     /gene="yhdP"
                     /locus_tag="ROH59_001920"
     CDS             complement(31612..35412)
                     /gene="yhdP"
                     /locus_tag="ROH59_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HDX4804403.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTSITSGGGNDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKET
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWIPEQDVGGKDNKRS
                     DELRIRASNLELAGLEGVRPLVAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLNNDKGFQLDGRNIDVKAKAVHARGGFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINGDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPAAVNEALSGSVAWDGKVGIELPYHAGATYNVELNGDLKNV
                     SSHLPSPLAKPAGEPLSVNVKVDGNLNSFELTGQAGADNYFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTR
                     GDSTQSSPFPTTERISFRGWPDAQIRCAECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFARLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
     gene            complement(35480..36949)
                     /gene="rng"
                     /locus_tag="ROH59_001921"
     CDS             complement(35480..36949)
                     /gene="rng"
                     /locus_tag="ROH59_001921"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HDX4804404.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            complement(36939..37532)
                     /gene="yhdE"
                     /locus_tag="ROH59_001922"
     CDS             complement(36939..37532)
                     /gene="yhdE"
                     /locus_tag="ROH59_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HDX4804405.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV
                     RKINGSFHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            complement(37541..38029)
                     /gene="mreD"
                     /locus_tag="ROH59_001923"
     CDS             complement(37541..38029)
                     /gene="mreD"
                     /locus_tag="ROH59_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDX4804406.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            complement(38029..39132)
                     /gene="mreC"
                     /locus_tag="ROH59_001924"
     CDS             complement(38029..39132)
                     /gene="mreC"
                     /locus_tag="ROH59_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDX4804407.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGITQPTPQQPATGNAVTA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            complement(39198..40241)
                     /gene="mreB"
                     /locus_tag="ROH59_001925"
     CDS             complement(39198..40241)
                     /gene="mreB"
                     /locus_tag="ROH59_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HDX4804408.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            complement(40546..42486)
                     /gene="csrD"
                     /locus_tag="ROH59_001926"
     CDS             complement(40546..42486)
                     /gene="csrD"
                     /locus_tag="ROH59_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HDX4804409.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLLSNDFSTLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGTND
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIILMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLCEIQNAREQHSRLDT
                     LIRSYAAQDMKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     LVEEQFFSLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIASQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGRVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLLISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRRRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            42638..43612
                     /locus_tag="ROH59_001927"
     CDS             42638..43612
                     /locus_tag="ROH59_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDX4804410.1"
                     /translation="MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRILPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPARRA
                     QAWQRLVTDLPESFYTQAAKEISLAEAPKFAEAIINNQIQGRTLVKVN"
     gene            44589..45059
                     /gene="accB"
                     /locus_tag="ROH59_001928"
                     /gene_synonym="fabE"
     CDS             44589..45059
                     /gene="accB"
                     /locus_tag="ROH59_001928"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDX4804411.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            45070..46419
                     /gene="accC"
                     /locus_tag="ROH59_001929"
     CDS             45070..46419
                     /gene="accC"
                     /locus_tag="ROH59_001929"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDX4804412.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA
                     SGGGGGRGMRVVRSDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            complement(46511..47557)
                     /locus_tag="ROH59_001930"
     CDS             complement(46511..47557)
                     /locus_tag="ROH59_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDX4804413.1"
                     /translation="MKNEIWSWIGDLSQVAGIKHYELRSGRAKGTEAFDVRTGAGLAF
                     TVVKDRALDIAWASYKDTALSFITPNGVVAPAFFESQGNGFLRSFYAGLLTTCGLSYI
                     GTPCEDEGETLGLHGRLAATPAEEVGYRTERTDDSIEFVINGKVRETRLFGENLTLER
                     TIRCRYGENVMRIEDKVTNHGFTRQPLQILYHFNYGWPLLSPQAEILLSAKSITPRTP
                     HAAEGLTSHLEICTPQPGFDEQVYYLTLNSDSQGMSKVALVNAELGWGIYEKFDTMQL
                     PNFIQWKNLGAGEYVMGLEVSNSFPDGRDKERAQGRLPFIEPGETKKYCFELGIVDGD
                     AEISALKAEIAGYR"
     gene            complement(47554..48516)
                     /locus_tag="ROH59_001931"
     CDS             complement(47554..48516)
                     /locus_tag="ROH59_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX4804414.1"
                     /translation="MSKVFTIGEILVEIMASKIGQPFDQPGIWNGPYPSGAPAIFIDQ
                     VTRLGVPCGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDR
                     DFIFNIKNAACGKLSAQHVDENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIVKANGG
                     VISFDPNIRKEMLDIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPERAIAGFLEE
                     GVKEVIVKRGNQGASYYSANEQFHVESYPVEEVDPTGAGDCFGGAWIACRQLGFDAHR
                     ALQYANACGALAVTRRGPMEGTSRLMEIETFIQRHDMSIREAAQ"
     gene            complement(48538..49527)
                     /locus_tag="ROH59_001932"
     CDS             complement(48538..49527)
                     /locus_tag="ROH59_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804415.1"
                     /translation="MTEKTLASPKPSGIPIANNFKKVFRQYGGILSGMVVLIILFSFI
                     NDSFFTANNITNIILQVSIIAITAYGMTYVLLLGDIDLSVGSTIALIGTFAALGASWG
                     IPFVLLVPLSIIAALALGMINGGLTAIAGIPSFIVTVATMGIFRGIAYIVTDGMPIMI
                     KDDAFLALGNGEFLYIPIPIWILIILLLINHFILTKTTFGRKIYITGGNKEAAIYSGI
                     NVTRLKIKVFMITAVLAGISGMILASRLYSGQPNSALSYELDAIAAAVLGGTSLNGGY
                     GTVVGTVIGALTIGVINNGMNLMNVPYFYQMVVKGLVILVAVYFDVRNKRKRS"
     gene            complement(49528..51027)
                     /locus_tag="ROH59_001933"
     CDS             complement(49528..51027)
                     /locus_tag="ROH59_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDX4804416.1"
                     /translation="MTDVILDVSHIAKTFGHVQALKDITLSLRKGRVHTLLGENGAGK
                     STLMKILAGVYPPTQGTITLRGETITINNPQHSRQLGIAIIFQELSLSNNMTVAENIY
                     ANNEPRRFGIINDKKMLADCQNLLAELGIPLDPLEMVGNMSMAHRQLVEIAKALSYAA
                     DVVIMDEPTSSLSDNEAEILFNIIEKLKQRGCAVIYISHRMDEIMRISDDISVIRDGE
                     YIATHEKKNSDIQHLIAQMVGREMKNIWPARLGEKPDENVPAKLEVKNLSHPSLFKEV
                     SFAVRPGEVLGFFGLVGAGRSDVMKALFGLVSYHGTVLIDGKEVRIANPKQAIDHGIA
                     FVTENRKEEGLVLMHDVNMNTHHVAFQYNASRMGLINHRQEEAKTLQSIARMNTKVSS
                     VHQAVGALSGGNQQKIVLSKWLEKTPRILLLDEPTRGVDVGAKFEIYNVIRQLAAAGT
                     AIILVSSELPEVMALSDRLVVMRNKTIADIYSCENLTQTQVMTAATGVR"
     gene            complement(51088..51978)
                     /locus_tag="ROH59_001934"
     CDS             complement(51088..51978)
                     /locus_tag="ROH59_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDX4804417.1"
                     /translation="MKNIKLLGSAMLVSLALFSQSSLAKEYKIGASLLTQQHPFYIDL
                     ANAMKEEAKKDNVNLSVSIANQDLNKQLSDVEDFITKKVDAIIISPVDSKGVQAAIIK
                     ADKAGIPVITVDVAAEGVPVVSHVATDNYAGGVEAGKLMGKLLSGKGTVAIISYPALQ
                     SVVARVDGFKKGLSDTPDIKIVAEQPGITRAEALTTAQNIMQANANLNGLFGFGDDAA
                     LAAVIAAKSAHNDNIKIIGFDGMKEARDAVDSEKTFAAVIRQYPDQMGAKAIDAAVDH
                     LNGKPVEKMIPVQPGVYTGK"
     gene            complement(52014..52868)
                     /locus_tag="ROH59_001935"
     CDS             complement(52014..52868)
                     /locus_tag="ROH59_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose bisphosphate family class II aldolase"
                     /protein_id="HDX4804418.1"
                     /translation="MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSP
                     VMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLDHHEESDDIFNKVRAGIRSVM
                     IDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLRVDEKDSAYTSPAAA
                     TEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDV
                     QHCIRRGICKVNVATELKIAFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIG
                     VCGSEGKI"
BASE COUNT        13108 a        14266 c        13044 g        12609 t
ORIGIN      
        1 aatcatttaa gttttgctat cttaactgcg tgcggcctga aaaacagtgc tgtgcccttg
       61 taactcatca taataattta cggcgcagcc aagatttccc tggtgttggc gcagtattcg
      121 cgcaccccgg tctagccggg gtcatttttt agtggctttt gccacccacg ctttcagtac
      181 ttctacgtcg tgacgccact cttctttcat ctcttcaatc cattcaccga cgttatcttc
      241 ccaggcggga aggtcaggag actgaatttg ctgacccagc tgttgcagat ggcgtaaccc
      301 cactgacccc gccgcacctt taattttatg cccttcctca acaatgcctt ttttatcctg
      361 cgccgtcaga ttcgactcca gcacgctgac atagcccggc atcattctct caaacaccgc
      421 taacccgtcg gtgatcagct tcggtcctac aagttcgaga tactgttcca gcatgggaat
      481 atcgagcaat gcttctgatt tactgttctc ttctgtcgtc accgtactct cctcatcatc
      541 ctgggtatcc cagaatttct tgatcatcgc ggttagcgcc ggaacagaaa gcggcttact
      601 cagcacatca tccattccag cattgaggta ctcttgcttg tctttcagca cgttagcggt
      661 taaggccacc agcggcggta aatcctcgcg cggataacgc ttcgtcagtt cacgagagat
      721 atccagcccg gtcatatctg gcaactgaat atccagcaat accaggtcgt attcgcccgg
      781 tttaaacatc tccagcgccg ccttgccggt catggcgaca tcaacgctgt tacctaattt
      841 ttccagcaca gaacgcgcga caatcacgtt cagttcaatg tcttccacca gcagcacatt
      901 cagcgccggt aaaggcatat cgtcttcatc aaacgcatca tcaacctctt ctgctaccga
      961 cggtgcgtgg atcgtcaacg taaaggttga acctttgccc tgttcgctgg taaccgtaat
     1021 atcgccgccc atatttttcg ccagacgacg agaaacggcc agaccaatac cggtgccggt
     1081 ggcaggttta ccgccatgac tgtctttcac ctggtaatac atggcgaaga ttttatccag
     1141 ctcatcctgc ggaatgccga taccagagtc ttccacttca aaatgcagca tatcgccttc
     1201 atcgtagcgc acgcgcacgg taacctggcc ttgctgagtg aatttgacgg cgttactgat
     1261 gaggttccac aagatctgcc gtaaacgcgt cccgtcggta atgacctgat gcggtaatgg
     1321 cagcgtcggc tccagattaa agcgcaatcc tttttgttgc gcctgcaatg cggagagatt
     1381 ttccagatcg gcaaggaagc tggtgaaatc aaccggctga ttatcaagct ggaccttgcg
     1441 ccgttccatc ttatccatgt cgataatatc gttgaagata ttccccagcg tgacagccga
     1501 aacatggatg gttttgagat atttttcctg ctcggcggtg agttcagtat ccagcagaat
     1561 gcggctcagg ccgacgatac cgttcagcgg tgtacgcaat tcgtgactga tggtggagat
     1621 aaacgtcgtt ttgtcgcggc tggcgcgttc aagcgcatcc tgataccgct tacgctcggt
     1681 aatgtcgcga ccaaagccca tcaaaccgtg acgtttaccc acgcggtcgt agtacggcac
     1741 tttacggatt tcaaagcagg ctttgcgtcc gtcgggataa tccagccact gctcataggt
     1801 cagtgacaca ttatgacgga acactttttc atcggtttca atgactttcg cagcggcttc
     1861 tggtgagtaa acatcagcag gtttcaggtg aaccagttgt ttttcgcttt ttccggtcag
     1921 cagctccatc gcgcggttac agccggaaaa ctctttatct tcgttacgat aaaaaaccag
     1981 gtcgggtgaa gcgtcaagga aggaacgtaa gaatgaggat tgctgctcga gctgaatttg
     2041 tgtctcttcg cgctctttga tttcaatttt cagttggccg aaggtttcct gcagttctgc
     2101 ttccgctttt tcacgaacgg cgatttcctg atttagctgg gcaatattat cttttaactg
     2161 aacgttgagg ctcaaatcgc gctcgcgcat ctcctccagt ttttgcacca gtcgtgacag
     2221 acgttgtcgt gactcctcca gttgctcgac gaccaccgat agaaagtaga ccgcccacgg
     2281 cgtaatcagc aaaccaaaga agatagaacg aataacatca atgctttcga cctgaccatg
     2341 cagcaccatg gttaccgcca tttgtaccac aatggcaaga acgacgaggg ccagcgccag
     2401 caacattgag aagcgcacca gacctaactt catcatcagg tcaacataat actgcgccag
     2461 cagacgaatt tgcttcatta gggaattcct tcacgacaac ctgccccaat aatacccaat
     2521 tctgacagtt acgttataaa ttgtgtgaga aatgcggaat tcccctcaat ggcctacgcc
     2581 gttggaggta gccacggacg tcccagcgcc gatccctgta cgccatgttc attcagataa
     2641 cgatccagct cgaccattcc cgtccatcga ttttcgcacc acagcggagc aagcagcgtc
     2701 gggcgacggg cgctggcgga aatacggtgg tagataactt ccggtggcgt atggcgaatc
     2761 atttctccgg cagtgagcgt gtaatcctcc agttcaattc cgttcaaacg ccccgcttcc
     2821 caggctttcg ccataatgct gcctttcact atatgcagcg gatgcagctt tatgccgtcc
     2881 acgccggttt caaccactcg ctccagcgtt tgcaaacatt cagcctgccc ttcgccaggc
     2941 aggccaacaa ttaagtgaga gcacaccttc agcccacgct cacgcgccag ctgcgtcgtg
     3001 cgctgatagc aggcaaaatc atgaccgcga tttatgcgat gcagtgtttt gtcgtgggcg
     3061 gtttgtagcc ccagctccag ccacacttcg tagccctggt ccttatattc gcaaagcaga
     3121 tccagcaccg catccggcac gcagtccggg cgggtaccaa cacacaaacc gacaatattg
     3181 gcctggctca ccgcctgctg atacatcgaa cgcagcacct gaacttccgc aaaggtgctg
     3241 gtatacgcct gaaagtaggc cagatagcgt ttagcgcggt taactaaatt cgcctggtgc
     3301 gccagttgct cggcaatgga acgatgctgc tgcgcttcat cggcaaacga ggcaacatta
     3361 cagaatgtgc agccgccacg cccgatggta ccgtcacggt tagggcagct aaaaccgccg
     3421 tgcagcgtca gcttatgcac cttttgccca taacgacggg tgagatcacc accaaacata
     3481 ttgactaatt tctgtaactg cataatctga tagaccgcgc cttgaaaaga ggccaaagcc
     3541 tgccattttt agcccaattc ggcgatgacc tggatcaatc gtcccagcct gcttttatca
     3601 actgcataac caatcaaaat taccgaaatt tcatgcacaa tcacataaat cactgttgct
     3661 tatcttgtgt cagatttttt tatcttctta tggattttag gcaaaaacag tagcatgaaa
     3721 cgttattacc aattaaggca gtataaaatg ctggctttct catcaattca aggcaggata
     3781 agggttaaca cgcctttatg acagtcagga attggctgtt tctctaacga cacccctttt
     3841 agccttaaat agaaaatcca ctttaatttc atacaattaa taaagaattt tgcgctaaag
     3901 cacatttctg taccaataag cttgccattt gacctgtatc agctttcccg ataagttgga
     3961 aatccgctgg aagctttctg gatgagcagc ctgctcatca tatttatgca gtaattgaga
     4021 tcccctcttc accgtattaa ccgatgcgaa aaggacaaca agggggcgaa tgcgaggtgc
     4081 gcgtatgaca cgcaaacccc gtcgccacgc tcttactgtg cccgtgcgca gcggttcgga
     4141 agtggggttc ccgcagagcc tgggggaggt tcacgatatg ttgtacgata aatcccttga
     4201 gagggataac tgtggtttcg gcctgatcgc ccacatagaa ggcgaaccta gccacaaggt
     4261 agtgcgtact gcaatacacg cactggcccg catgcagcac cgtggcgcga ttctcgccga
     4321 tggtaaaacc ggtgacggtt gcggcttgct gttacaaaaa ccggatcgtt tttttcgcat
     4381 cgttgcgcag gagcgcggct ggcgtttagc aaaaaactac gccgtcggga tgctcttcct
     4441 gaataaagat cctgaactcg ccgctgccgc acgccgcatc gttgaagaag agctgcaacg
     4501 cgaaacgttg tcgattgtgg gctggcgtga tgtccccact aacgaaggcg tgctgggtga
     4561 aatcgccctc tcctctctgc cacgcattga gcaaattttt gtgaacgccc cggcaggctg
     4621 gcgtccgcgc gatatggagc gccgtctgtt tatcgcccgc cgccgcattg aaaagcgtct
     4681 cgaagccgac aaagacttct acgtctgtag cctgtcgaat ctggtcaata tttataaagg
     4741 tctgtgtatg ccggcggatc tgccgcgctt ctacctggac ctcgcggacc tgcgtctgga
     4801 atcggccatc tgcctgtttc accagcgctt ttccactaac accgtaccgc gctggccgct
     4861 ggcgcagccg ttccgctacc tcgcgcataa cggtgaaatc aacaccatca ctggtaaccg
     4921 ccaatgggcg cgtgcgcgta cctataaatt ccagacgccg ctgatccctg acctgcacga
     4981 cgccgcgccg ttcgtcaacg aaaccggctc tgactccagt tcgatggata acatgctgga
     5041 actcctgctg gcaggtggga tggatatcat ccgtgccatg cgtctgttag tgccacctgc
     5101 ctggcagaac aacccggata tggacccgga actgcgtgcc ttctttgact ttaactccat
     5161 gcatatggag ccgtgggatg gcccggcagg catcgtgatg tctgacggtc gttttgccgc
     5221 ctgtaacctc gaccgtaacg gtctgcgtcc ggcgcgctac gtcatcacca aagataagct
     5281 cattacctgc gcctctgaag tcggtatctg ggattatcag cctgacgaag tggtcgaaaa
     5341 aggccgcgtg gggccaggcg aactgatggt tatcgacacc cgcagtgggc gtattctgca
     5401 ctcggcagaa accgatgacg atctgaaaag ccgccaccct tataaagagt ggatggagaa
     5461 aaacgtccgc cgtctggtac cgtttgaaga tctgcccgat gaagaagtgg gtagccgcga
     5521 actggacgac gacacgcttg ccagctacca gaaacaattt aactacagcg cggaagagct
     5581 ggattcggtg atccgcgtac tgggtgaaaa cggtcaggaa gcggtcggtt cgatgggcga
     5641 cgatacccca ttcgccgtgc tctccagcca gccgcgcatt atttacgact acttccgcca
     5701 gcagtttgct caggtaacca acccgccaat cgacccgctg cgcgaagcgc atgttatgtc
     5761 gctcgccacc agtatcggtc gtgaaatgaa cgtcttctgt gaagcagaag gccaggcgca
     5821 ccgtttaagc tttaaatcgc cgattctgct ctattccgat ttcaaacagc tcacgacgat
     5881 gaaagaggat cactaccgcg cagatacgct ggatatcacc tttgacgtca ctaaaaccac
     5941 gctcgaagcg acggtgaaag aactgtgtga caaagccgaa aaaatggtac gtagcggcac
     6001 cgtgctgctg gtgctctccg accggaatat cgctaaagat cgcctgccgg ttccggctcc
     6061 gatggcggtt ggcgcgatcc agacccgtct ggtcgagcaa agcctgcgtt gcgatgccaa
     6121 catcatcgta gaaaccgcca gcgcccgtga tccgcaccac ttcgccgtgt tgctgggttt
     6181 cggcgcgacg gctatttatc cataccttgc ctatgaaacg ctgggccgcc tggtagacac
     6241 ccacgcgatt gccaaagatt atcgtaccgt gatgctcaac tatcgtaacg gcatcaacaa
     6301 aggcttgtac aaaatcatgt ccaaaatggg catctccacc atcgcctctt accgctgctc
     6361 gaaactgttt gaagcggtcg gtctgcacga tgatgtcgtg ggcctgtgct tccagggggc
     6421 agttagccgc attggggggg cgagctttga agacttccag caggatctgc tgaatctgtc
     6481 gaaacgagcc tggctggcgc gtaagcctat cagccagggc ggcctgctga aatatgtaca
     6541 cggtggcgaa taccacgcct acaacccgga cgtggtgcgc acgctgcaac aggcggtaca
     6601 gagcggcgag tatagcgact atcaggaata cgcgaagctg gttaatgagc gtccggcaac
     6661 cacgctacgc gatctgctgg caattacgcc gggtgaaaac gcggtcaaca ttgctgatgt
     6721 tgaaccggca agcgaactgt ttaaacgctt cgataccgcc gcgatgtcta tcggtgcgtt
     6781 aagcccggaa gcccacgagg cgctggcgga agcgatgaac agcatcggcg gtaactcaaa
     6841 ctccggcgaa ggcggtgaag acccggcgcg ctatggcact aacaaagtgt cgcgcatcaa
     6901 gcaggtagcg tccggtcgct ttggggttac tccggcgtat ctggtcaatg ccgacgtcat
     6961 tcagataaaa gtcgcccagg gcgcgaagcc gggtgaaggt ggtcagttac cgggtgataa
     7021 agtcactcct tacattgcca aactgcgcta ttcggtgccg ggcgtgacgc tgatctcccc
     7081 gccgccgcac cacgatatct actctattga ggatttagcg cagctgattt tcgacctcaa
     7141 gcaggtcaat ccaaaagcga tgatctccgt gaagctggtt tccgaaccgg gcgtaggcac
     7201 catcgcgact ggcgtggcaa aagcttatgc cgatttaatc accatcgcag gctatgacgg
     7261 cggcaccggc gcaagtccgc tttcatcggt gaaatacgca ggctgtccgt gggagctggg
     7321 gcttgttgaa acccaacagg cgctggttgc caacggcttg cgtcacaaga tccgtttgca
     7381 ggtcgatggc ggcctgaaaa cgggtgtcga tatcatcaaa gcggcgattc ttggcgcgga
     7441 aagttttggc ttcggcactg gcccgatggt agcgcttggc tgtaaatatc tgcgaatttg
     7501 ccacctgaac aactgcgcca cgggtgtagc aactcaggat gacaaactgc gtaagaatca
     7561 ctatcacggc ctgccgttca aagtgactaa ttactttgag tttatcgccc gtgaaacccg
     7621 cgagctgatg gcacagctgg gggtaacgcg tctggtggat ctgattggtc gcaccgacct
     7681 gctgaaagag ctggacggtt tcaccgccaa acagcagaaa ctggcactgt cgaagctgct
     7741 ggagactgcc gagccgcatc ctggtaaagc gctctactgc accgaaaaca acccgccgtt
     7801 tgataacggc ctgctgaacg cgcagttgct gcaacaggca aaaccgtttg tcgatgaacg
     7861 ccagagcaaa accttctggt tcgatatccg caacaccgac cgttctgtcg gcgcgtcgct
     7921 ttcaggctat atcgcccaga cgcacggcga tcaggggctg gcagccgatc ctatcaaagc
     7981 gtacttcaac ggcactgcag gccagagctt cggcgtgtgg aacgcgggcg gcgtggaact
     8041 gtacctgacc ggtgatgcca acgactatgt tggtaaaggc atggcgggcg gcttaatcgc
     8101 cattcgtcct ccggttggtt ccgccttccg cagccatgaa gcgagcatta tcggcaacac
     8161 ctgcctgtat ggcgcgaccg gtggtcgtct gtatgccgca ggccgcgcgg gtgaacgttt
     8221 cggcgtgcgt aactccggtg ctatcaccgt ggtagaaggc attggcgaca acggctgtga
     8281 atatatgacg ggtggtatcg tctgtattct gggtaaaacc ggcgttaact tcggcgcggg
     8341 catgactggc ggcttcgctt acgttctcga tgaaagcggc gatttccgca aacgcgttaa
     8401 cccggagctg gtcgaggtct taagcgttga cgatctggcg atccatgaag agcatctgcg
     8461 tggtcttatc accgagcatg ttcagcatac cggttcccag cgtggtgaag agattctggc
     8521 gaactggtca accttcgcca ctaaatttgc gctggttaaa ccgaagtcca gtgatgtaaa
     8581 agcactgctg ggtcaccgta gtcgtagcgc agcagagttg cgcgtgcagg cgcagtaagg
     8641 ggtagcaaca atgagtcaga atgtttatca atttatcgac ctgcagcgcg ttgatccgcc
     8701 aaagaaaccg ctgaagatcc gcaaaattga gtttgttgaa atttacgagc cgttttccga
     8761 aggccaggcc aaagcgcagg ctgaccgctg cctgtcgtgc ggcaacccat actgcgagtg
     8821 gaaatgcccg gtacacaact acatcccaaa ctggctgaag ctcgccaatg aggggcgtat
     8881 ttttgaagcg gcggaactgt cgcaccagac aaacaccctg ccggaagttt gcggacgtgt
     8941 ctgcccgcaa gaccgtctgt gcgaaggttc ctgcaccctg aacgatgagt tcggtgcggt
     9001 gaccatcggc aacattgagc gttatatcaa tgataaagcg ttcgagatgg gctggcgtcc
     9061 ggatatgtcc ggcgtgaaac agaccggtaa aaaagtggcg attatcggcg caggtccggc
     9121 gggtctggcg tgcgcggatg tcctgacgcg caacggcgta aaagcgatcg tcttcgaccg
     9181 tcacccagaa attggcggct tgctgacctt cggtattccg gctttcaagc tggaaaaaga
     9241 ggtaatgacg cgccgccgtg aaatcttcac cggcatgggt attgaattca aactcaatac
     9301 cgaagtgggc cgcgacgtgc agctggacga tctgctgagt gattacgatg ccgtgttcct
     9361 tggcgtcggg acttatcagt caatgcgcgg cgggctggaa aacgaagacg ccgatggcgt
     9421 gtacgcagcg ctgccgttcc ttatcgccaa caccaaacag ttaatgggct ttggtgaaac
     9481 ccgcgacgaa ccgttcgtca gcatggaagg caaacgcgtg gtggtccttg gcggtggcga
     9541 cactgcgatg gactgcgtgc gcacgtctgt acgccagggg gcaaagcacg ttacctgtgc
     9601 ctatcgtcgt gatgaagaga acatgccggg ttcccgccgc gaagtgaaaa acgcgcggga
     9661 agaaggtgtt gagttcaaat tcaacgtcca gccgctgggt atagaagtga atggcaacgg
     9721 caaagtcagc ggcgtaaaaa tggtgcgcac agaaatgggc gaaccggatg ccaaaggccg
     9781 tcgccgcgcg gagattgtgg caggttccga acatatcgtt ccggcagatg cggtgatcat
     9841 ggcgtttggt ttccgtccac acaacatgga atggctggca aaacacagcg tcgagctgga
     9901 ttcgcagggg cgcatcatcg ccccggaagg cagcgacaac gctttccaga ccagcaaccc
     9961 gaaaatcttt gctggcggcg atatcgtccg tggttccgat ctggtcgtta ccgccatcgc
    10021 cgaaggtcgc aaagcggcag acggcattat gaactggctg gaagtttaag cgaggtaaca
    10081 atgaattcgc cagacagtgt ctggcgaatt tataaaacga gctatccaac taaattttaa
    10141 gccattaaat cagccttaac cttcactacc acctttttaa tctcaccagg ttcgccaaca
    10201 acgcatcccg gtttatgcgg ttctcctggc ataaacacgg cgaacattcc cggtttcagg
    10261 atgatggctt gctcgttttc aatggcgctg caaagctgat aatcatcttc atggtggaac
    10321 tcttcacact gacgcgcagt gcctgccatg ccaaacagaa tccgttcctc accgtttaat
    10381 aacagctgga tatcaatgta ttgttcgtgc aattcggctt ttttctcaac gggcgattga
    10441 gtattaaatg tcatgacatt cataaagata ttgtcgccct gtaattcgta acggccaggc
    10501 gctttttctt gcggtctggc agctaatgcc aacgttaacg cgtcctgtaa cgcaggatgt
    10561 aatccggcag acggtaatga ctgtacttca cccatcatca taatatttct ccctgggcca
    10621 acagcgcagc cccaagtaaa cctgcatcgt ggcggtagtg cgccgccagt aaatcaacat
    10681 gaaatgccgc tggctcctgc gccagatacg tttccaccag cgccagatac ccttctgcca
    10741 gaccaacgct gccaccgacc accacgcact ggcaatcagt tgtggcttta atatcagcga
    10801 tcagccttgc aagcgtacgt gcggagcggt gaatcagttg ctgcgcctgc tcatcgccct
    10861 gcccggcgcg cgtgaaaata gttttcgcat tcgcaccagc caactccccc tgcgctgcag
    10921 ctgcaatgcc gcgaccagaa gcaatcgctt ccacgcaacc tgtgcgtcca cagccgcaga
    10981 ctggaccatg cggatcggca agcgtatgcc cgatatgccc cgccagaccg ccagggccgg
    11041 tacgcagttt accgccgctc actacaccgc cgccaacgcc ggtggaaaca gtgataaaca
    11101 ccatatcggt tatatcgcca tccagcgcct gatactccgc ccatgctgcg gcctgcgcat
    11161 cattaatggc aatggtcggc aaattggtaa gttgctccag cgttttgact aacggaaagt
    11221 gtaacaatcc accgagatta tgcggattca gcgccagcaa gctgccgtcg cgaataattc
    11281 cggttgaagc gatagcaacc cgctgcgcat gtgcttgcaa cggagagact aatgcggata
    11341 aggcatcacg cagcgcctgc ggagtctggc tggcaggcgt aggaagttct cggcgatcgc
    11401 ggatctgccc gtcagcgcca atcagcgcgg cggcaagttt agtaccgccg atatcaatcg
    11461 ccagtgtggt catagcaccg cctttttcat cgctgtgttg taccactgac aaatgtgttc
    11521 aagacgcgta atggcagaac cgaccgtcac cgcccacgcg ccgtggcgca tcgcatccgc
    11581 cgcctgagca ggcgtgttgt aacgcccttc ggcaatcacc cggcatccgg cgtcactcaa
    11641 cgttttcacc agcgccagat ccggctcttc tggcgtttca ggcgtggtat agccagaaag
    11701 cgtagtgcca ataatttcgg ctcccagctt ttggcatgcc aggccgtctt ccggcgttga
    11761 gcagtcggtc atcgccagta aaccgtgatg gtgaatacgt gccagcagcg tttcaacagg
    11821 caccggacgc ggtcggtcag tgccgtcaat ggcgataatg tccgcgcccg cctgcgccag
    11881 cgcatcaaca tcttcaatat aggccgtgat gcgtaccgga gaatcctcca gatcgcgctt
    11941 cacaatccca ataatcggca cgctcaccac cgcacgcgtg gcttgcagat ttgccacacc
    12001 ttcaatacga atggcaaccg cgcccgcctg ctctgccgct aatgccatgg cagcgacgat
    12061 ttcgggttta tcgagcgggc tgtccggaac cggctggcag gagacaatca ggccaccgtt
    12121 agcagcgatt ttttgatcca gttgtgcaag taacgacata catcttccct tagcgaaagg
    12181 cccggtacag agaccgggca acaggattaa cttttggttt tgactaaatc gtttttggcg
    12241 ctgccaaatg gcacggcacc gctaaatggt ttgccgtcga tagcgtcatg agtacgcaat
    12301 gcttccgggc gcaaccaacg ctgaacacga gaaggcatat ccagaccaat cagcaggatc
    12361 accacaaacg ttaaactaaa cgagagcgag ccaagtgccg ttcccagatc cagacgttga
    12421 gcgatcaacg cgccgaggat tggagctagt gcaccgccca gtgcgccaac gttgtaggta
    12481 aagcccagcc ccgccgcacg ctggtcggta tcgaaataac cgccgatcag tttcggtaaa
    12541 atccctgaga tgccctgacc aagcatttgc tggaagaaca gtaacaaacc gagcacccag
    12601 acgtttgcgc cgccaatcgc aaataccgga ataatcagca gctgcgaggc cagcagacta
    12661 caaacgtacg ctttgcgggt tcccagccag tcaccgagga agccaccgac gcagcacccc
    12721 accgccgcgc caaagccact aaagaacagc acattggcga cagtatgcgg gtcataagcc
    12781 agatcggttt tcagatacgt tggcagcagc gcctgaatcg gccatgagta gaggaaagcg
    12841 aacaacacga ccaccatcag cattacgccc gttggccagc gtttgcccgt actctgcacc
    12901 ataaagctga taaagattgc ggcgcataac agcccgagta cagcgacgat tgcggcattt
    12961 tgcaggttac cggcgaagca gaaccacagc gcagtagccg ccgccagcgt cattacgata
    13021 ttggcaatgc gatgttcacc acggtaaaga atgtctacca tcgtgcgtac tggtgcttta
    13081 cccccgtgtt tctctttcca gtcttccgct tccgggatgt ttttacgcag ccagagagca
    13141 aagatgattg gcaaaatgcc gataaagaac agcgcacgcc agccccagac cggaaccacc
    13201 agactataga cctgagcggc aacgacggcc cccactgaga agcctgaaat cagaaaacca
    13261 ctggctttgt tacgcagatg ctttggccag ctttcaatga cataggtggc gctggaaccg
    13321 tattcacccg ccatccccat gccgatgacc agacgagcga taaacatggt gatgtagcct
    13381 ggcgcaaagc cgcaggccag cgtcccggcc gagaagagaa cgatgctggt gaccattgcc
    13441 agacgacgcc cgtagcggtc acccatagcg ccgagcatca ggccgccgaa ccagcgagag
    13501 ataaaggctg cggagatcag acttgccgcc tgcaccgtcg tcagcccgaa ttcaccctgt
    13561 acttcggtga gtaccagggc gattaaaacg aaatcaaaac cgtcaagcag atatcccaac
    13621 caggcagcgg aaaatgcccg ccattgtgcg cggttaagat ggcgatacca cgggatattc
    13681 tgggttgtag tactcattgt gagtctcccg cggtgggcga tgcccacacg ctttggtatg
    13741 aaaattgtag ggtacagatg cgtttatttc ccctcacccg gtaggggcga gcgaggggaa
    13801 acaactcacc cgcgctcttg catcaactgc tgagccagcg ccttcagttc tggcagatat
    13861 ttttcatcta ccggaccaaa cggtttgcgg cacagcggca cagaaacgac atccatataa
    13921 tgcaggacag ttttcagccc acggaatacg ccagttttga tcagtaaatc aatgactttg
    13981 ttgcactcag tttgcagttt ctgcgcggtc tggatatcgc cttctttcag cgccttcacg
    14041 atcccctgat aacgccagcc catgatgttg taagtgctgc cgataccgcc gtctgcgccc
    14101 gccagaagac cagaggcgaa gatttcgtcg taaccgttat agagcaccag atcaggatgt
    14161 tcacgacgga tctgctccat ctgatagaga tcgccagagg tctgtttcag cgcacctacg
    14221 ccaggcagcg taaccaaggt gttgatctga tccagggtca gttttacccc gctcagggct
    14281 ggaatgttgt acaccaccat cggcaaccca tccgctgaat caataattgc ccgatagtga
    14341 tcgcagtgtt cttcaaagct gaaaggatag tagaacggcg tgacggcgga gacggcatcg
    14401 aagccataac gtttagccga tgccgcaagt tgttggcttt cggcggtgct gacgcaaccg
    14461 acatgggcga tgagtttaat cttacctttc gcctcttcag cgacgatttc cagtacctgt
    14521 tcgcgctcgg aaaggctttg tacaaaggct tcgccggtcg aaccacccac gtacaaaccg
    14581 tcgatgccct gctgaatatt gaactgaacc aggcggcgca gactcgcttt atccagtgct
    14641 tgttgttggt caaaaggagt caggagtgca gccattacgc cacgtaaatt cgttgccata
    14701 aatacctctg aagtgatgct tgtctgataa acgatatacc tttatacctg ttataccaga
    14761 tcaattaagc aacaccccat acagaaagct tataatgcga tctgcttcac taaagtggca
    14821 ttatttcttt ttgttggtgg tctgaccgaa ggcgtgccag gtagcagaga cgctgttgag
    14881 atgcgattgc aacgcgcgat cggcttcgtc aggatcatga cggcggatcg cgtcaacgat
    14941 cgcaatatgc tgttgatagc taacgttgtt atgctcatgc agagcctgat cggtcacggt
    15001 tggacgtgcg gcgattagcc agtcgagcag ggcaacgtgg atcgccatga agattgggtt
    15061 acccgggatc tccgccagaa cgcggtggaa atcaacgtct gagcgaatga atgccgcgtt
    15121 gttatccagc gactgactgt tgatttccag tgcttttgcc agcaaatcga tttgctcatc
    15181 ggtggcgtgt tcagccgcat agcgcaccag gctggattca aagaacagac gtaattgttc
    15241 gaaatgggca atcccaccag gatgagaaag gaaatctttc gccatgccgg aaagctcgcc
    15301 gatgatggtg tccgcagaag gacgtgagac gcgggcacgt tcgccgttgt ttatttgcac
    15361 cagacctttg cgttttaacg ctgccagcgc ttcgcgcacc gaaggacgcc cgacgttaaa
    15421 gaacgccatc agttcgcgtt cagacggtaa ttgttcacct tcgccaaatt cacgacggcg
    15481 gatcatctgt tccagctctt cttccaccat ttcggagagt tttttacgcg ccagcgggcg
    15541 gctgcgcaag ttgcgcccga tagtggtagt agaatcttca gcttgcggat caaatgcgtt
    15601 cataggactc attcaggaaa atgcgttagc ggataataac gacgctatcg tagcacagta
    15661 tcaaagtcag gcgaaaagat gacagatagc aaaacaggcc acatgggcct gttttcattt
    15721 tacttcacaa cgcgtaatgc cggtcgacca ccgcgtggtg gctgcggagg ttcatcgtca
    15781 ggatgagttt catcatcgtg atctggcttg tcgccatcga taaccgacat aacggtttcg
    15841 ttgtctgccg atgcctcttc atcattcatg atgctggcat cttcatcgta ggcagcttca
    15901 ggctcaaaca tcgtgcctgc gccattttca cgggcgtaga tagccagcac ggcagccagc
    15961 ggcacagaaa cctgacgcgg aatgccacca aagcgcgcgt taaagcgcac ctcatcattc
    16021 gccagttcca gattgccgac agcacgcggc gcaatgttga gtacgatttg cccgtcacgc
    16081 gcatattcca taggaacctg cacgccaggg agcgtcacat ccaccaccag gtgcggcgtg
    16141 agctggttat ccagcaacca ctcatagaat gcacgcagca gatagggacg acgtggtgtt
    16201 agctgtgaca aatccataca gattaactcc ggcccagacg catttcacgt tctgcttcag
    16261 ttaaagaagc aaggaaagag tcacgttcaa agacgcgggt catatagcct ttcagctctt
    16321 tcgcacccgg gccgctgaac tcgatgccca gttgcggcag acgccacagc agaggagcaa
    16381 ggtagcaatc gaccaggctg aactcatcgc tcaggaagta cggcttctga ccgaagaccg
    16441 gcgcaatcgc cagcagttct tcgcgcagtt gcttacgtgc ggcatcggct tcagaagctg
    16501 aaccgttgat gatggtgttc atcagcgtgt accagtcttt ttcgatgcga tgcatgtaca
    16561 gacggctttc accgcgagct accgggtaaa caggcatcag tggcggatgc gggaaacgct
    16621 catccagata ttccataatg atgcgagatt cccacagggt cagctcacga tccaccaggg
    16681 tcggaacgct ctgattcggg ttgaggtcaa tcagatcctg aggcggattg tccttttcca
    16741 cgtgttcgat ctcgaaactt acacctttct cagccagcac aatgcggacc tgatggctat
    16801 agatgtcagt aggaccggaa aacagcgtca ttaccgaacg tttgttggca gcgacagcca
    16861 tgaaaacctc caggtatagt cagaattttt actgctacca gccaccaggt ggccagtcag
    16921 aagttgtgtt acccagtaag gaacgactct ctttgttcga aaatcaaaca aaaaatgagc
    16981 aatacccgac atttgggcag aaaattggat gatagtttac cagattttgc gacctttgtg
    17041 gtgagtcgat gccggaaatg gggaaaaaga gatgcgcttt agtctgaaat agttgactta
    17101 gtcccttatt ggcgatgtgg tttttgtttt acctgtctgt caggtggcag caaaaagcaa
    17161 ctttccattt tttacgctga tgcagatttt agccataaaa aaacccgccg aagcgggttt
    17221 tttcgcaaat tgttttctgc cggagcagaa gccaattaac gtttggagaa ctgcggacga
    17281 cgacgtgctt tacgcagacc gactttctta cgttcaacct gacgagcgtc acgagtaacg
    17341 aagccagctt tacgcagttc agaacgcagg gactcgtcgt attccatcag agcgcgggtg
    17401 ataccgtgac ggatcgcacc agcctgacca gagataccac cacctttaac ggtgatgtac
    17461 aggtccagtt tctcaaccat gtcgaccagt tccagcggct gacgaactac catgcgagca
    17521 gtttcacgac cgaagtactg ttccagagaa cgttggttga ttacgatttt accgttgccc
    17581 ggtttgatga aaacgcgagc tgcggaactt ttgcggcgac cagtgccgta gtattgattt
    17641 tcagccattg cctataatcc cgattagatg tcaagaactt gcggttgctg tgccgcgtgg
    17701 ttgtgctcgt tacccgcgta aactttcagt ttacggaaca tagcacgacc cagcgggcct
    17761 tttggcaaca tgcctttaac cgcgatttca atcacacgct caggacggcg agcaatcatc
    17821 tcttcaaagg tcgcttgttt gataccaccg atgtggccgg tgtggtgata gtacactttg
    17881 tcagtacgct tgttgccggt tacagcaact ttgtcagcgt tcagaacgat gatgtaatca
    17941 ccggtatcta cgtgcggagt gtattccgct ttgtgcttac cgcgcaggcg acgagccagt
    18001 tcagtagcca gacggcccag agttttaccg gtcgcgtcaa caacatacca gtcgcgtttt
    18061 acggtttctg gtttagctgt aaaagttttc attaaaagct tacccaataa atagttacac
    18121 gttggtgaac acccaaacgt cttcaattgt tgaggttcac acgacaaagt ccggcaaacc
    18181 taccccttcg aatagcctat gccagcacac aaaaagtttc gggaaaaaaa actttcttgt
    18241 aacgtggggt cgcaggatta tagagaagtc ggggtcaaag atcgacccct ttttgtgatt
    18301 tgtggcaggt tttaccccgc caaatgctcg cgcttcaaat actcttcgct ttgcatctct
    18361 tgcagacgtg acaggcaacg ctggaactca aacttcagcc gctcgccctg ataaatttca
    18421 tacagcggca cttctgcact caccactaat ttgacatggc gctcgtaaaa ctcatccacc
    18481 agcgcaataa agcgccgcgc ttcgctctcc atcaaccgcg tcataactgg tacatcaaac
    18541 aacatgaccg tgtgaaagag gcgtgagagc gcaatatagt catgctgact gcgggcgtcg
    18601 acgcacagcg tagtaaaaga aaccgccagc gtctggttct cgacgcccat tgtcgccaat
    18661 ggccgatggt tgatttctaa cgtcggtgaa ttttctcgtt tcgcccccgc cagcgccaac
    18721 catagtttat ccatttgcgc ccgggtttca tcgttgaggg gcgaaagcca cagatgcgcc
    18781 tgagtgagtg tacgcaggcg ataatcaaca ccagcgtcca cgttcattac atcacaatgc
    18841 tgtttaatgg catcgattgc aggcaaaaaa cgcgcacgtt gcaggccatt tcgataaagt
    18901 tcgtccggcg gaatatttga cgtcgctacc agggtaatac cgcgggcgaa cagggctttc
    18961 atcagaccgc caagtagcat ggcatcggta atatcagaaa caaaaaattc gtcaaaacag
    19021 agcacgtcag tttctgcttt aaagcgatcg gcaataattt ccagcggatc ggtctgcccc
    19081 tgcaaagcag ttagctcttc atgcacccgc agcataaaac ggtgaaagtg caggcgctgt
    19141 ttccgctctc ccggcagact ttgatagaaa aggtccatca gccaggtttt cccgcgtcct
    19201 acaccgcccc acatatataa gccacgcact ggcatatgct ttgtgtcttc gcgtttaccc
    19261 cacagcttac cgacccgcgc cattagccca ctcgtcctgg gggctggtgg cgtgctattg
    19321 acgagttcct tataaataat ttccaggcgg ctgacggcct ctttttgaac gtcgtcgggt
    19381 tgatggctgc cttcattgag cgccttcagg tattgcgatg ttggggtaac gctttgcatg
    19441 atcttattgt tattccttga ataatcggtg cgccgttgtt cacggttgac gaaaaaaagg
    19501 ccgttctaca ctacgcgata tgctgtcggg attccacttc tgtggaatta acggttatag
    19561 tggcataatc agccgcaggc atggagcctg aagccaacac cctacggaaa caaaagacaa
    19621 cgggagatgt tcatgacctg ggaatatgcg ctaattgggt tagtcgtcgg catcattatt
    19681 ggtgctgtgg ccatgcgttt tggtaatcgt aaactacgcc agcaacaggc gttgcagtac
    19741 gaactggaaa agaataaagc tgaactggac gagtatcgcg aagagctggt tagccacttt
    19801 gcccgcagcg cggaattact ggataccatg gcgcacgact atcgccagct gtatcagcac
    19861 atggcgaaaa gctccagtag cctgctgccg gaactgtctg cggaagcaaa cccgttccgt
    19921 aatcgtctgg cagagtctga agccagcaac gatcaggcac cggtgcagat gcctcgcgac
    19981 tattctgaag gcgcatccgg cctgctgcgt actggcgcga agcgcgacta atttattttt
    20041 ggggcgcagc cattgcgccc tcctcttctc tccctccccg actatcattt aatctggtgt
    20101 ctcattgtta gccgtctgaa aattcaataa catcaaactg ttttgaatct cttttcttat
    20161 cattcaggta cgagagcagg aataatgaaa aaacaaaccc agctgttgag tgcattagcg
    20221 ttaagtgtcg ggttaactct ctcggcgtca tttcaggccg tcgcgtcgat tccaggccag
    20281 gttgccgatc aggcccccct ccccagtctg gctccaatgc tggaaaaagt gcttccggca
    20341 gtggtgagcg tacgggtgga aggaacggcc agtcagggac agaaaatccc ggaagaattc
    20401 aaaaagtttt ttggtgatga tttaccggat caacctgcac aacccttcga aggtttaggc
    20461 tccggtgtca tcatcaacgc caataaaggc tatgtgctga ccaacaacca tgtgattaat
    20521 caggcacaga aaatcagtat tcagctcaat gatgggcgcg agtttgatgc aaaactgatt
    20581 ggtagcgatg accagagcga tatcgccctg ttgcaaattc aaaacccgag caaattaacg
    20641 caaatcgcta ttgccgactc cgataaattg cgcgtcggtg attttgccgt ggcggtcggt
    20701 aacccatttg gccttgggca aaccgctacc tccgggatta tatctgcgtt aggccgcagc
    20761 ggtctgaatc tcgaaggtct ggaaaacttt attcaaactg atgcctccat taaccgcggc
    20821 aattccggtg gtgcgctgtt aaaccttaac ggtgagttaa ttggcatcaa cactgcaatc
    20881 cttgcgcctg gcggcggtag cgtcgggatt ggatttgcca ttcccagtaa tatggcgcga
    20941 acactggcgc agcagcttat cgactttgga gaaatcaaac gcggcctgtt aggtatcaaa
    21001 ggcaccgaga tgagtgccga tatcgccaaa gccttcaacc ttgacgtgca gcgtggcgcg
    21061 tttgtcagcg aagtgttgcc aggttctggc tcggcgaaag cgggcgtcaa agcgggcgat
    21121 attattacca gcctcaacgg caaaccgctg aatagctttg ctgagttgcg ctctcgtatc
    21181 gcgaccaccg agccgggcac gaaagtgaag cttggcctgc tgcgtaacgg caaaccactg
    21241 gaagtagaag tgacgctcga taccagcacc tcttcgtcgg ccagcgctga aatgatcacg
    21301 ccagcgctgg aaggtgcaac gttgagcgat ggtcagctaa aagatggtgg caaaggtatt
    21361 aagatcgatg aggttgtcaa aggaagccca gctgctcagg ctggcttgca aaaagacgat
    21421 gtgatcattg gcgtcaaccg cgatcgggtg aactcgattg ctgaaatgcg taaagtgctg
    21481 gcggcaaaac cggccataat cgccttgcaa atcatacgcg gcaatgaaag cctctaccta
    21541 ctaatgcgtt aatgtcgtaa accgggcatc aggctgacgt gtgatgtccg gttaactcgt
    21601 ggtatgctgc tgccgttccc ttttttaacg atgcctccat catgtttgtg aagctcttac
    21661 gttccgttgc gattggatta attgtcggcg ctattctgct ggttgccatg ccttcgctgc
    21721 gcagccttaa cccgctttcc actccgcaat ttgacagtac cgatgaaacg cctgccagct
    21781 ataatctggc ggttcgccgc gccgcgccag cggtggttaa cgtttataac cgcggtttga
    21841 acaccaactc tcacaaccag cttgagatcc gcaccctggg atctggtgta atcatggatc
    21901 aacgcgggta tatcatcacc aataaacacg tgatcaacga cgccgatcag atcatcgtcg
    21961 ccttacagga tggacgtgtt tttgaagcgt tactggttgg ctctgactct ctaaccgatc
    22021 tggcggtgct gaaaattaac gccacaggcg gtttaccaac gattccgatc aatccacgcc
    22081 gcgtaccgca cattggcgat gtggttctgg cgatcggtaa cccgtacaac ctcgggcaga
    22141 ccattaccca ggggattatc agtgccacgg gtcgaatcgg tctgaacccg accgggcggc
    22201 aaaacttcct gcaaaccgat gcttccatta accacggtaa ctctggcggc gcgctggtga
    22261 actcgctggg cgaactgatg ggcattaaca cgctgtcgtt tgataagagt aacgatggcg
    22321 aaacgccgga aggtatcggc tttgcgattc ctttccagtt agcgaccaaa attatggata
    22381 aactgatccg tgatggccgt gtgatccgtg gctacattgg cattggtgga cgtgagatcg
    22441 ccccattaca tgcgcagagt ggcggcatgg atcaactgca agggatcgtg gttaacgaag
    22501 tgtcgcctga tggcccagcg gcaaatgcag gcatccaggt caacgatctg attatctctg
    22561 tgaataacaa acccgctatt tccgccctgg agacaatgga tcaggtcgcg gaaattcgcc
    22621 ctggttcggt gatcccggtt gtcgtgatgc gtgacgataa acagttaaca ttgcaggtca
    22681 ccattcagga atatccggcg accaactaag gtcagcgtaa aaaaacaaaa accggagtct
    22741 gtgctccggt tttttattat ccgctaatca attacttatt aacgaactct tcgcccaggg
    22801 cgatatcttt cttcagcgta tccagcatac cttccagcgc gttctgttca aatgcgctca
    22861 gagtaccgat agatttacgc tcttccacgc cgtttttacc cagcagcagc ggttgagaga
    22921 agaaacgagc gtactgaccg tcgccttcaa cgtaggcaca ttcgacaacg ccttgttcgc
    22981 cctgcagtgc gcgaaccaga gacagaccaa aacgtgcagc tgcctggccc atagacaggg
    23041 ttgcagaccc gccaccggct ttcgcttcaa ccacctcagt acccgcgttc tggatacgtt
    23101 tggtcagatc agccacttcc tgctcggtaa aactaacgcc aggaacctgt gacagcagcg
    23161 gcagaatggt aacaccagag tgaccaccaa taaccggcac ttcaacttcg cctggctgtt
    23221 tgcctttcag ttccgcaaca aaggtgttgg aacgaatgat atccagcgtg gtaacgccga
    23281 acagtttgtt tttgtcataa acaccggctt ttttcagcac ttcagcagca atcgcaactg
    23341 tagtgttaac cgggttagtg ataataccaa tgcacgcttt cgggcaggtt ttcgcaactt
    23401 gctgtaccag gtttttcacg ataccggcgt taacgttaaa caggtcggaa cgatccatac
    23461 ccggtttacg cgctacgcct gcagagataa gaacgacatc tgcaccttcc agcgccggag
    23521 tcgcatcttc acctgaaaaa cctttgattt tcacagcagt agggatatgg ctcagatcga
    23581 cagccacacc gggagtcact ggagcgatat catacagaga gagttctgaa cctgaaggca
    23641 gttgggtttt taacagtagt gcaagcgcct ggccaatacc gccagcagcg ccgaggactg
    23701 cgactttcat cctaaactcc ttattatatt gataaactaa gatatgttgc tccgctgccg
    23761 cgaccttaat ccacaaaatt gccgtttaca atgaccacat ctcaagaatg tgtagtcacg
    23821 caagtttagc gtttatgcat ttaattgccg taatcaggaa cctaacttac gtaattaaca
    23881 gtcacttatg cattagcgca acattccaac aggtggtgac aatataccct accgctcagc
    23941 caaaacaata tcaatttgat aacaattaat ttacttttaa gcagaatttg caggccgtga
    24001 cgcaggcatg tttctcaata acgaaatttg ataaaatccc gctctttcat aacattattt
    24061 cagccttctt cagggctgac tgtttgcata aaaattcatc tgtatgcaca ataatgttgt
    24121 atcaaccacc atatcgggtg acttatgcga agctcggcta agcaagaaga actagttaaa
    24181 gcatttaaag cattacttaa agaagagaaa tttagctccc agggcgaaat cgtcgccgcg
    24241 ttgcaggagc aaggctttga caatattaat cagtctaaag tctcgcggat gttgaccaag
    24301 tttggtgcgg tacgtacacg caatgccaaa atggaaatgg tttactgcct gccagctgaa
    24361 ctgggtgtac caaccacctc cagtccattg aagaatctgg tactggatat cgactacaac
    24421 gatgcagttg tcgtgattca taccagccct ggtgcggcgc agttaattgc tcgcctgctg
    24481 gactcactgg gcaaagcaga aggtattctg ggcaccatcg ctggcgatga caccatcttt
    24541 actacccctg ctaacggttt caccgtcaaa gagctgtacg aagcgatttt agagctgttc
    24601 gaccaggagc tttaatctct gccccgtcgc ttctggcggc ggggaaaatg ttgcttttgc
    24661 ctatcaaccc actgctttcc cctgcgattc atttaacgaa tagtgcgttt tactgcgaca
    24721 tatcattcac acaatgaata catatagtaa aaaagcacat tatgcaaaat tcattatcta
    24781 attgaaaata ctataattaa caataaatga tcgtgttttt aattcttttt tgttattaaa
    24841 attcacattt ttaacactta gtatcaactg aaacagttag cgtggtatta attagttcaa
    24901 taattagtgt atacttgatt ttgtgatatg ggtcacgaaa caaaggccca gctaaaagat
    24961 tatgtcgagg taaaaatcat gaaaatcaaa accactgttg ctgcattaag cgtactttct
    25021 gttctctctt tcggtgcatt cgctgccgac tccattgatg ctgcacaagc acaaaatcgt
    25081 gaagcaatcg ggaccgtatc cgtaagtggt gtggcgtctt cgccaatgga tatgcgtgaa
    25141 atgctgaaca aaaaagcgga agagaaaggc gcaacggcct accagattac tgaagctcgt
    25201 agtggtgaca cctggcacgc tacggctgaa ctgtacaaat aaaccctcat cgtcttgtcc
    25261 gacgatattg cccccggttc gggggctttt tttgcgctaa tgacgaacat taaaacgcaa
    25321 atgcccttcc agctcttcct ctgcctcatc aaacagcaat attaacgcgc caaaacggcg
    25381 acgcgttttc tctcccagat gaacaaattc aatctcaagt ggtagcggca ggacatcgtt
    25441 cattaacaca tcccatagtg agtcgagatc gcgtacctta tctttcgcca gaccaaaggt
    25501 ttggctaaag tcacgataaa aatcctcctg actctcaatc tcatcaaaat caaaggtata
    25561 aatattcatc tgttgccacc gtcacgtttc gcggcgagtt ctgccgttca tcgctaagta
    25621 tagccatgaa aaaaccgacg cttcaggcgt cggttttgac ttaactatcg gtcaacgcat
    25681 gttgatactt atggagcata cccgtaagcc gatgtactgg ttccgtcacc tgcggtggcg
    25741 cttgccagat gcgtagcttt tcctggtaga tttccagttc ttccagcaac tggccaaagt
    25801 accgacgacg tttatcatcg ctacgggcag atatcacatg gtctgctgtg cggcgcattt
    25861 gtcggtgaaa cgccgataaa tcctcgttaa ccgggatcgg cgcatcacgc aggcgctggt
    25921 gcgcgataat catcgtcagc gccaggcgaa atttcggcaa atcccctggg aacttattca
    25981 tcagcaaaaa cagctgctga taaagtgccg ggaggtgatt ctctttacga cgtgccacat
    26041 tggtagtcat cgcggaaaca gcggcagaaa caaactgatt aagcagtaca cgtccagtcc
    26101 tgtcgcgcga tttatcccgc accagcaaaa taacggtgaa cgcgagcaca cagccgacga
    26161 tttgccctaa tgcgctgtcg agaaactgac tgaaatggaa agtcatcggg ttatccagca
    26221 cgataatgtt tatggtgctg gccaacgccc ccatcgagcc caatctccgt ttctgtactt
    26281 ctatgccgag gaaaaatccc agcactgcca ggctaataca cagcagcaac atgctctgtt
    26341 gggtattagg gataatcacc aaaaagtaga gcagccctaa cggcagcgct gccagcgtcc
    26401 cgtagataaa gtcgatcgcc accatgcatg gattcggcaa acgcattgcc agtgacgtca
    26461 cgaccgcaat catcaccatt gcaccactgc cggaagtcca gcccgtccac agccagaaaa
    26521 gcgtgcccag aatgcaagaa agtgtggttc gccagaagtt aaccattgca tgatgacgtt
    26581 cggctgactc tacttttact tccggttcgc cttgcaggat ctcttcttcg gtggcgttga
    26641 tttttgtgtt actgataacg ccgcgcttga gaagctgata acgcgttgcc gccgcgaccc
    26701 aactataaat ggtaacaggc gtttcccgtt ccccggtcca ggcgatcact ctccgcaggc
    26761 gtttgagctg cttgtggacg tcctgcgcag tttctaccgg cgtgtcaaaa aattcgcgga
    26821 aagtatcagt gatcaattcc gggcgcgtat tctgaataag ataagtttcg caggattggg
    26881 taatcagcgt cagcgatagc gtattgatcg cttttaaacg tcgattagcc cgcgcccagc
    26941 gggaagattc catattcagg ttgctgcgca taccttgtaa cgccgtagta cgtcgcacca
    27001 gatcgcccca ggctttatcg acaacttcac catcgccatg cttgatacag agttgcatta
    27061 attgatattg cgcgaccagc aaactttcca gctctcgatc cacttcttgt ttgatcgatc
    27121 gcggagaaaa gagcaaatcc gccataattg cacacacaat accgataacg atctcgctac
    27181 aacgttcgac ggcaaactgc ggcgtaagca atggttccgg ctgaatggtg atcacaatga
    27241 tcagcgcggt ataaccggcc agcccccacg catacgagtt ttctattcgt accagcgagg
    27301 atatccaggt acaaaaaccg gcccagatac agcacaccag aatcatcaat aatggtgctc
    27361 ggatcatcgc aatgatgatt accagtccgg caatacagcc aataaatgtg ccgatgatgc
    27421 gcaaaaagcc acgatagcga atagcgccag aatacggttc acctcccgca gcaaaggccg
    27481 gaccggcggc aacaatcgcc gctgtcagta ccgcccagcg tggcgtttcc agctggaagt
    27541 gaaagccaac aaacagcgcc agtacaatgg cggtcgccag ttttaccgca aagcgaatat
    27601 gttgattagc aatggagaaa atacccatcg tgattaacca aactcacgca ggcgatgagc
    27661 cattttacgg aagaacgaat cctgactttc gtcgcgatct tgtttgccag tgactaccac
    27721 cgtagcagtg gtgcccgcag gccagatgtt ctcttgctgg ttgtcgagac gaatacgtac
    27781 cggaacacgt tgcgccaaac gtacccattc aaggttagag tcgatggtcg ccatcccttt
    27841 gtcgtcacgc gtgctgctgg cattggtgac ccctgcggca acactatcaa cagtcccttt
    27901 cagcactttg ttactgccaa gcggcgtgat ctccgcacga tacccagggc gcaccccttc
    27961 cagcttagtt tcttccatat aggccagtac atagaaggag ttctgtttca ccagcgcaac
    28021 cgccgttgat ccacgggtaa taaactcacc ggtatagacg ttgaggttgg tcacccagcc
    28081 atctgctggc gcgcggatca ccgtgcgttc aagatccagt tttgccagat cgcgggtcgc
    28141 ctgcgctttc gctaactgat gcagaaccgt ttgtagtacg ttgttggcct ggtcgatctc
    28201 ttcgcgggac atcgcctgca caccgagacg gttacgacgt ccggcctcct ggcgtttctc
    28261 ctgtgccagt acctgataat aagcaacatc ggcttgcgct tcctcaagcg ccttttgata
    28321 gcgcggctgg tcgatggtga acagtacctg tccttttttc accagctggt tatcatgaac
    28381 attcacctgg gtaatgagtc cagaaacgtc cggcgcgatc gcaacgacgt cagcgctaaa
    28441 gcgcgcgtca cgcgtccacg gggattcggt gtaatagacc caggcattaa aaattgcgat
    28501 gaaggccaga atgactaata cgaccgtgat ggccgtacgg gagaattttc ttattagtgt
    28561 tttcacttca acctcaaacg aacagtcgcg atatcaaata aaacaagcag caatagagcg
    28621 cggtgttgaa caacgccgga tgccagacaa agtcgtagat acctgttggc acaagtaccc
    28681 ggcgcaccag ccagaaaatc gccagtgata aaagcaattc gaaaaatatc ggtgggaagg
    28741 acagcccaaa caccacgata acgggaaaca gactcatgtt gaccttggtt gtatagagag
    28801 agcaggcgtt attattttca gcatctgtcg ccgcagagaa gggcatagaa agccgggcga
    28861 gagcaacatt gctgtagatt gatatttaat atattaacgt aactgttatg ctgttatcta
    28921 tattatgtga tctaaatcac ttttaagtca gagtgaataa tggaacgact aaaacgcatg
    28981 tcggtgtttg ccaaagtagt tgaatttggc tcttttaccg ccgccgccag acagctacag
    29041 atgagcgttt cgtccatcag tcagacggtg tcaaaactgg aagatgagtt gcaggtaaag
    29101 ctgttaaacc gtagcacacg cagcattggc ctgaccgaag ccggtagaat ttactaccag
    29161 ggctgccgtc ggatgctcca tgaagtgcag gatgttcatg agcaactgta tgccttcaat
    29221 aacaccccca tcgggacgct gcgcattggc tgttcttcaa ctatggcaca aaatgttctc
    29281 gccgggctga cagcaaaaat gctgaaagaa tacccaggtt tgagcgtcaa tctggttacc
    29341 ggaattcctg cccccgacct gattgccgac ggtctggatg tggtgatccg cgtcggcgcg
    29401 ttgcaagatt ccagcctgtt ttcccgccgt ctgggcgcga tgccaatggt ggtgtgcgcc
    29461 gcaaaaagct atctcacaca atacggcata ccggaaaaac ccgccgattt aagtagtcac
    29521 tcatggcttg aatacagcgt gcggcccgac aatgaatttg aactgatcgc accggaaggg
    29581 atctcgactc gcctgatccc acaaggaaga tttgtgacta atgatccgat gacgctggtg
    29641 cgctggctga cggcgggtgc cgggatcgcc tacgtgccgc tgatgtgggt gatcaacgag
    29701 atcaatcgtg gggagctgga gatcctgctg ccacgttacc agtcagatcc acgcccggtt
    29761 tatgcgttat ataccgaaaa agataagctg ccgctgaagg tacaggtcgt gatcaactcg
    29821 ctgacggatt attttgttga ggtcggtaaa ttgtttcagg agatgcacgg gcgcgggaaa
    29881 gagaagtaat taatattgta ctgttacgtt gtacaaacct gtgccgacgg gttcccctaa
    29941 ccccagaggg gcgaggggac cgttcgtgca cggagaagga ttaattatcc ttctgaaaat
    30001 actgaaatta ttacgcagta ccgccaacag tcaggttatt aactttcagc gttggctggc
    30061 ccacgccaac cggcaaactt tgcccttctt taccgcagac acccacgccg ttatccagtt
    30121 tcaggtcgtt gccaaccatc gaaatctgct gcatggtttc gataccggaa ccaatcaacg
    30181 ttgcgccttt caccggctta gttactttac cgttttcaat cagatacgct tctgaggtgg
    30241 agaaaacgaa tttgccggag gtgatatcca cctgaccgcc accaaagttc ggtgcataga
    30301 taccgtactc aacggattca ataatttcct gcggggtcga tttacccggc agcatatagg
    30361 tgttggtcat acgcggcatg ggcagatggg cgtaggattc acggcgaccg ttgccagtcg
    30421 gcgtcatccc catcaaacgc gcgttgagtt tatcctgcat gtagcctttc agaatgccgt
    30481 tctcaatcag cacgttgtac tggcctggcg taccttcgtc atcaatcgcc accgaaccac
    30541 ggcgatcgac catcgtgcca tcatcaacca cggtacacag ttctgaagcc accaactccc
    30601 cgacctgtcc actaaatact gaagtgccac ggcggttgaa gtcgccttcc agaccgtgac
    30661 ccaccgcttc atgcaacagc acgcccggcc aacctgcgcc aagtactacc ggcatggtgc
    30721 ccgctggtgc agcaacggca gaaagattga ccagcgccat acgcactgct tcttttgccc
    30781 acgcatccgc acggacttcg ccgtcgagat cggcaaggaa gaactcataa ccaaaacgac
    30841 cgccgccacc actggcaccg cgttcgcgtt tgccatcttc ttcgaccaaa acgctcacgg
    30901 aaagacgcac cagcggacgg acatccgccg ctagtgtgcc gtcggtggcc gcaaccagaa
    30961 ttaattcata gacaccactg aggctggcag tcacttcctg tacgcgcttg tccgcttcgc
    31021 gggcaacctt atcgacgcga cgcaggatat ccaacttctc ttcacggctc atgctttgca
    31081 gcggatctac cgaggtatat aacgggctat gctctaccgc gcccagcgtc tgtactttgc
    31141 catcaccact atcacggacg atggtgcgcg ccgcttgtgc actctgttcc agcgccagca
    31201 ggctgatttg gtcagcataa gcaaatccgg ttttttcacc actgattgca cgcacaccaa
    31261 cgccctgatc gatgttgtaa gaaccatctt taataatacg gtcttctaaa acccaggatt
    31321 cgtgatagct cgactgaaaa tagagatcgc cataatcaag gcgacgttcg gccagttgac
    31381 cgaggatcgc gaacaagtcc tgatgtttca ggccgttcgc cgctagcaat tgttcactta
    31441 ccaggttcag actcatcgtt tttgctactc gttagttact gcagtagagg attttttacg
    31501 gctgccggat gcggcgtgaa cgccctgtcc ggcctacggt tatgttctgg ctcgttggcc
    31561 tttggcaacg attatcatat gagattgggg caattacgcg ccctcgtcaa atcattgcgc
    31621 tttttcttta cgcggttgtc gcaacacttc gttgatttgc ggatcgtcca gcggacccga
    31681 aatgtgatag cgcaaaatgg agactttgct ccacagcggt cccagcactt tactggcggc
    31741 aaacactgcc gcgccaacaa tggggttaac cgcaaaggcc gcagccacac ccaccgtcgc
    31801 agaaatctct ggtgcgacaa ccgcttccat attcaggtcg cgacgtacca gatttaccga
    31861 ccctttcatg gcgatgtccg cttccaggcc atccaccagc gtgtcgtcgg tgtgcataac
    31921 gccgtcttta atccacgcgg tgctgcgaat ggagtcaaaa tagaaccctt cgccaaaagt
    31981 gtctctgaaa tcaaaacgca gcttacgcat cagggcatct acgctcaata agcgcagcaa
    32041 ttgcccggca tgtccggtat tgatttcggt aatttcgcct ttacccagtt gagtatgaat
    32101 gatgccattc aacgtcgcct catctggctg ccagggtgct ttgcgccagt gtaaatcgta
    32161 atccacatta aatgacgact ggcgtatggg cgtcgtgaca ccaaaaaatt ctgcggcggc
    32221 atcaattttc tgcccgcgca gttttccttt cagcgaggtt cgttcattcc ccggattgtt
    32281 aacccattca ccatcggcag tgagccgcgc aaaaccagta tcaatcagtc cattagtcag
    32341 cgttaacgta tcgccagaaa tggtgatatc actgtcaatg cgaccgaatt tttgccccca
    32401 gaaccagcac tctgcgcatc gtatttgtgc gtctggccag ccacggaagc taatgcgttc
    32461 cgttgtcggg aaaggtgatg actgtgttga atcaccacga gttttcgcca cgcttgggtt
    32521 gtaataaaga tatttgatat tcgccagcca cggcgcgtta ttacgcatcg ccagcgtggc
    32581 gttgatttca cgcccttgcg cctcaaccag ggtgccattt gccgtcggtt gcgaaacaat
    32641 actcaggtta ttccattgct gatttcccag cgacaacata ggcgtacgta acgttatgtg
    32701 ttgtgggaaa ctcgctgcac caccgacact ctccgccgcg cctttctgga acagggccag
    32761 ccactcggca ccattcatcg gcggcatatt gagttcaacg ccactttgtt ccggcaacgg
    32821 cgggagcgtt ttactgtctg ccgcccaaat agcacgatcg agcgtcagct tttgaccgag
    32881 caaccagcgg ctattgaaat agttatccgc accagcctgt ccggttaatt caaagctgtt
    32941 gagattgcca tcaaccttaa cgtttaccga tagtggttca cccgcaggtt tggctaacgg
    33001 tgaaggtaag tgactgctca cattcttcaa atcgccgttc agctctacgt tatacgtcgc
    33061 gccagcatga taaggcagct caatgcccac tttaccatcc cacgccacgc tgccacttaa
    33121 tgcttcgttc accgctgcag gcagaacgcc ggttttcgct ggttgccagt taccgttgag
    33181 attcaccgcg acctggtagg cttttgcccc ttctttggtg gaaaaatcca cgttcaacgg
    33241 ctgattaaac cagcttgctg tcagtggttc actttgcaga tcgccattga taaagctgaa
    33301 tttaccgctc aaatttttca gggtgctgtc gagtggtttg ataaacagac tgttattacg
    33361 cagcgtcact tcacctttcg cggttaccaa ctcgccgttc agcgggatat caagatgtaa
    33421 gcgagcattc acatcgccgt cgagctggag ttcttgcagg gtcgcaccca gggaatcttt
    33481 cagcggtgtc tcatcaaagt aagggccaac ggctttaccc ggacctttaa tgtcagcgtc
    33541 aatcagcagt ttttcttttg agtagtcagg gatcactgcg gtgagattac tcgcgcgcac
    33601 gccgcccaga ttaacgccat cggttttcat ccataaaccg tcgttaataa agtccagttc
    33661 aatatcaagg ttagttaatg caggccagtc cggctggaag gcaaacttcg cgttgcgcag
    33721 cggcaccagc acttcaaact gaccttcgtt gtgtttatag gggaagagtt gcggattgcc
    33781 accataaacc agcgtcgcgt tatccgcttc accgccctga atcgcgccac ttaagtaatc
    33841 aaccaggtct ttacccatca agttttccgg gaaatagcgc caggcttgtg aaccatcatc
    33901 ggtactgatg ccagccagaa tacccagcca gggttcatcg ttagcaggtt gcaggtaacg
    33961 aaaaccgccg cgcgcatgga cggctttggc tttaacgtca atattacgcc catccagctg
    34021 gaaacctttg tcattgttca gccagcttat cgttgcctgg ccgtcggcga tttccagtgg
    34081 cgcacggaat accgtttcgt aaggcatctt tgcctgcttc atcgacgcag taagcaaacc
    34141 attttctacg ctgccggaaa gcgtcccgga gaagtgttcc gcacccggta ataatttcca
    34201 ttgcttccag gccagatcgc tccacgatgc ctgaaaacgg gtcttgtctg ccgcctgaag
    34261 cgggatatcc agcgccagag tgttaatctt gccgctcggt tgtgtggagc gccaaacatc
    34321 acccagtgca ggtgaaagtt tcgcgaccag cgggcgtacg ccctccagcc ctgccagctc
    34381 cagattactg gcacgaatcc ggagttcgtc actgcgttta ttgtctttgc cgccaacgtc
    34441 ctgttccggt atccaggcca gcgtcaatgc tccgctcggc cagggtttgc cgtccatcgt
    34501 gatccgtgta tcgggaatag agaactgcca tcccggattt tcacgcgtaa tatgcgcagt
    34561 cagattatcc accgacagcg tatgcgtttc cttctcgccc aaccagctgg caccgccctg
    34621 tttcagccag acgtcaccgc cggttacatc gcctttgtcg atcgtcatcc agccttcaag
    34681 ggagaactgt gccgtttcca gcgcaatatt gtcctgcatc catttaccga gccacggctt
    34741 caggtcgatg tcatccgcct ggagccagac gcgaccattg cttaacaacc cctcatcatc
    34801 gcgcaaatcc atacgcacct gcatcacgcc gtgctgtccg gtaaggctgg agaggcttac
    34861 caggccttcc gcacggtgtc gacgtggatc gttcagccag gtgagctgtg ggatcgccag
    34921 ctcggcgcgc tgaccggatg gcgtcaggaa actgacttca ctgtcgcgga gatcgaaatg
    34981 gtcaaattga cgaagaaaca gatcgctgat gtgactggct tccaggctat cattaccacc
    35041 gccgctggtg atagaagtgt tggtgcgaaa gcgcagctgc cagaaagtga ggtcgcgaaa
    35101 ctgccagcgc atatgtaaca ggctctgcca gacatccagc gccagggtaa cgcgtttaac
    35161 cgaaaattcg ccgccatctt ttagttctgc acggatgtcg tgcgcttcaa gcgtcggacc
    35221 aaaattctgc cagctggctg agagctgact ggcttctacc ggcatgccag tcgcggattc
    35281 tattttgttg aggatttccg gacgccaggc gtcaagatgc ggtaaagcaa tacgcaggcc
    35341 gctaaccagc agggcagcga tcacaacgag cgcggctcca gtaagcagta aaatccccgg
    35401 caatcgcctc acccgtcact ccttgtctgc taaaaatgtg actcaaaaac cctttgccgg
    35461 atggcggccc agcatctgtt tacatcatta cgacgtcaaa ctgctcctgg ttatagagcg
    35521 gttcaatttg tactttaacc tgtttgccaa cgaaaatttc cacttccgcc agcgagtgtg
    35581 actcttcgcc tttcaaggct tcggctactg ccggagaagc atagaccagg aaacggtcgg
    35641 agtcgtaagc atggtggaca cgaacaatct cgcgcatgat ttcatagcat accgtttcca
    35701 cggttttcac cgttccgcga ccgtggcagg ttgggcattc gttacacagt acgtgctcaa
    35761 tgctttcgcg ggtgcgttta cgcgtcatct ccaccagccc cagcgccgaa aaaccattaa
    35821 cgctggtttt cacccgatct ttgctcaacg cctgctccag cgagtgcagc acgcggcgac
    35881 ggtgatcttc attattcata tcgatgaaat caataatgat aatcccgccc agattgcgca
    35941 accgtaactg gcgagcgata gcctgcgtcg cttcaatatt ggtattgaaa atggtgtcgt
    36001 ccagattgcg atgaccgaca aacgccccgg tattgatgtc cacggtggtc atcgcttcgg
    36061 tctggtcgat aatcagataa ccaccggatt tcagttctac tttgcgttcc agcgctcgct
    36121 ggatttcgtt ttcgacatca aagagatcga aaatcggctg gcgtccggtg taatgctcca
    36181 gcttgctggt catctcggga atgtactctg aggtaaactc cagcaatgct tcgtaagtca
    36241 ggcgtgagtc aacgcgaatg cggtcgagtt cggcgtcggc gaaatcacgc agaacacgct
    36301 gcgccagcgc cagttcgccg tacagctgat aacgggtctg cgggcgtttt ttacgctcca
    36361 taactttggt ccagacgcgt ttcagataag cagcatcgga ggccagttcg gcctcgccaa
    36421 ccccttccgc tgcagtacgg atgataaacc cgccctgctc gtcgcaatac tctgcgacca
    36481 cttttttcag gcgttcacgt tctgattcgc tttcaattcg ttgggatacc ccaacgtgag
    36541 aagcccctgg cataaacacc agatagcgag aaggcagcgt gatatcggtg gtcaggcgcg
    36601 cacccttagt gccaagcgga tctttcacca cctgcaccat cagatcttgc ccctgacgga
    36661 ccagttccga gatgtcgcgc accgtgaatt gcttttgttc ttcacccgcc acacattcgg
    36721 tgtgcggcat gatgtcagat gcatgaagaa acgcggcttt atccagccca atatctacaa
    36781 aagccgcctg catacccgga agtacacgac ttacacgacc cttgtagata ttgcctacta
    36841 ttccgcgtcg cgcctcacgt tcaatatgaa tttcctgcag aataccgcca tcaatatacg
    36901 ccactcgagt ttccgaaggc gttacgttta ccaacaattc agccgtcatg tttatccctt
    36961 ttctcacgca gtgcgttaaa attacttaat aattcatacg tttcaaccag cggtaagccg
    37021 actacggcgt gaaagctgcc atttatcttc ctgacaaaac agccacccag cccctgaata
    37081 ccgtatgcac ctgctttatc taacggttcg ccgctggcga catagcccgc gatgtcttcg
    37141 tctgttaacg ttctgaaagt cacatcggtg accaccaggc aatcgagaat gtgctggctg
    37201 tcggccaacg ccactgccgt catcacctga tgggtctgac ccgataattt gcgcaacatc
    37261 tgcgccgcat gctctgcgtc gcgcggtttc tcgagcactt ctccattcag gataacgata
    37321 gtatccgcac ccagcaccgg gagatcctgc gccgtttgcg cgacacccgc ctgtgctttc
    37381 tcgcgcgcca gacgcacaac atactgctgc gcgctctcct gcggctgacg ctgctcctca
    37441 atgcccgtaa caatacgttc aaaggtcacg ccaagttgcg caagtaactc ctgacgacgc
    37501 ggagaaccgg aagctaaata cagagaagtc atagaaacct ttattgcact gcaaactgct
    37561 gacggacttt acgcatcagc aagaaaatcc acggccagag aacgccattg actacactac
    37621 tccagaacac ttccggtctg aaagagacgt taatcactaa aaactctgcc cagaaaacaa
    37681 taatatccac caccagcgaa agcaacatga cgaccagcgc ctgctgccat aatgcgaggt
    37741 tgcggaaaag ctggtatttc agcgccacca ggtaagcaat gatgctcatc gccaatacgc
    37801 gtacgccaag cgtcgagccg ctgatcagat ccagtatggc acccatcaca aaacctgtgc
    37861 ccacatttac gcgatggggc aaggccagga tccaatacaa caagatgagt aacacccagt
    37921 ttggccggaa aacaatcagg ttgtccggcc atggcatgat ttgcagcaac agcgcaatga
    37981 ggaaagagag ccagattacc cagcgtccct ggctacgata gctcgccact attgtcctcc
    38041 cggcgcacgc gcaggcggtt gagcaccact ttgcggcggc gtagcccttt gtggagagcg
    38101 attagcagcg ggctgtgtgg gcgcagcagg cgcagtaact gcatttcctg tcgccggttg
    38161 ctgcggagtc ggctgagtga tccccgttgc cggttcaggt aactttggcc ccatcgcgtc
    38221 tggcgaaggc aatacctgcg gcatcatctg catcagacgt tcattagcaa cacgatgcac
    38281 ctcttccggc gtcatcgggt tagcgccgtt acgatccgcg ccccacagca gcagcagata
    38341 acgcaaacgt tgcagtcctg cagtcggacg cgcctgaatc acagtataag cgcgctgggt
    38401 atcgagtttt acggaagaga caaccgcgac cggatagcct tccgggaaac gaccgcccag
    38461 accggaagtc accagcacat caccaacacg aatatccgta ttcgctggca gatgctcaag
    38521 ctgcaaatca tccgtacaac cgttaccggc tgcaattacg cggatatcgt tgcgcagcac
    38581 ctggattggc agcgcgtggg tcgcatcaca aatcagcagc acgcggctgg tcagtttagc
    38641 gacggccacc acctgaccaa caacaccttt gtcgctgata accggctggc cttcataaac
    38701 gccattaacg ctacctttat cgataacaac ttgatcgcta taaggatcgt taaccgtgga
    38761 gataacctga gtcaccattt tctgctcatc ctgacgcagc ggggaaccca gcagctcgcg
    38821 cagacgcgcg ttctcctgtt tgtattgtcc aagcatcagc agttcactgt ttttcagcaa
    38881 cagttcctga cgtaacgccc ggttttcaag ttctagttgg tcacgcgagg ccagcgtctg
    38941 cgatacgcca tccagcaatt cacgaggagc attggaaaca aagtagaaag gactgacggc
    39001 ggtatccata taagtacgga tttgactgaa cgtccccagg cggctgtcgg caataataat
    39061 gccgagcgcc accagcaccg ccagaataag gcgaatctgt agcgacgggc cacggctaaa
    39121 aattggcttc ataagttatg cgtattctcg tatcagacca ggcagggtaa acagacactt
    39181 cccctgcctg catccgatta ctcttcgctg aacaggtcgc cgccgtgcat gtcgatcatt
    39241 tccagcgctt tgccgccacc gcgcgccaca caggtcagcg ggtcttcagc aacaacgact
    39301 ggaatgccgg tttcttccat taacaaacgg tcaaggttac gcagcagtgc gccaccaccg
    39361 gtgagcacca tgccgcgctc ggagatgtcg gaagccagtt ccggcgggca ctgttccagt
    39421 gcaaccatta ccgcgctcac aataccggtc agcggttcct gcagtgcttc gaggatttcg
    39481 ttggagttca gggtaaaacc gcgtggaaca ccttctgcaa ggttacggcc acgaacttcg
    39541 atttcacgga cttcatcgcc cgggtaagcc gaaccgattt cgtgcttgat acgttctgcg
    39601 gtggcttcac cgatcagaga accgtaatta cgacgtacat agttgatgat agcttcgtcg
    39661 aaacggtcac caccaatgcg cacggaagag gagtaaacca cgccgttcaa ggagataaca
    39721 gcaacttcag tagtaccacc gccgatatca accaccatag aaccggtcgc ttcagaaacc
    39781 ggcaggccag caccaattgc ggcagccatc ggttcttcaa tcaggaagac ttcacgggca
    39841 ccagcgccct gcgcggattc acgaattgcg cggcgttcaa cctgggtcgc gccaaccggc
    39901 acacaaacca gaacgcgcgg gcttggacgc ataaagctgt tgctgtgcac ttgtttgatg
    39961 aagtgctgga gcattttttc agtcacgaag aagtcggcga taacgccgtc tttcattggg
    40021 cgaatggcag caatattgcc cggcgtacgg cccagcatct gcttcgcgtc atgacctact
    40081 gcagctacgc ttttcggtga accggcacga tcctgacgaa tggccaccac ggaaggctca
    40141 ttcaatacga tgccttgtcc ttttacataa atgagggtat tcgcagtacc caggtcaatg
    40201 gacaagtcat tggaaaacat gccacgaaat tttttcaaca tactaaggga taatcctgaa
    40261 agctggggcg gaaaagaaaa tccgcttact ttaccaacca cacgcagcag cgacaaggcg
    40321 caaaaatcat ctgctacggt gaaaattagt gcagttcgtt tcctttgtta caaatctctg
    40381 cctgagtcca gaaaggctta atgcatcagc agcattcctc gcctgtttgc aaccgcgtaa
    40441 ggtcattcat ctgcatatgt gctgcaacaa tctggcgagc agacaagcac actcccatga
    40501 gacgcagcgc gcgttattct acgtgaaaac ggattaaacg gcaggttaaa ccgagtatct
    40561 ttgtgaatat tttttcacgt tagtatcaag tggctgtgag gacgcgaaaa aatccccttg
    40621 cccacctgta acaccgcgct gaatcagggt ctgccactcg cttcgcgaac gcacgccggt
    40681 ggcgtaaacc tgggtgctgg tcccggagca ggcttccacc aggctttgaa ccagcagctg
    40741 gttctccgtt cgcttctcaa tgtttctgac cagccccgga tggagcttga gtaactcaac
    40801 attaagttct ttgatccaac tggtgcttac cagcgtcaaa ccagcctggt tgacggctac
    40861 ccgtacccct aaagcattca ctaaacgaat aacaggttgt aagcgactga tatgttgacc
    40921 aacatcggcc tctgcaagtt caataattat gcgtcttcgt tgcgattttt cacattgcat
    40981 taacgtatcg cgcagccaac gctgaaaacg cgggcgaatc agcgactcaa cggtaacctg
    41041 aatcgccaga ttttcctctg gccagtaacg caatagtgga ataagacggc tgattagcaa
    41101 gcggtcatac tcttccgata aaccaaactg caagaccatc ggcatatact ctgccgagct
    41161 aacctcttca ttaccatcga agatgcggca catgagttca cgatgatgaa cccggccttc
    41221 gcgagtaacc gccggttttt gataaaggcg cgggccgccg cgactgagca tttgctcgat
    41281 aagcgtacgc cagcgaacat taccgcgtcc tttttcaggc aacgagtcat cgtaaatagc
    41341 ccagctattg ccgccctgca atcccgcatt acgcgtggca gactctgcat gttccattac
    41401 ctgctcggta tcctgaccac tacgccaggc acagatacca atgtggatca tatcgtcgcg
    41461 atcgagcatt ttattgttcg gcaaggtatc gacggctttg attaactgac tggcgatgct
    41521 ctctgcctct tttagcgtcc ggtgcggtaa cagcgcagca aaatcactgc gatggtaacg
    41581 cgccagcagt gcgccagggt agcgcatcat aaatgtcgat agcagattcg tcagagagaa
    41641 gaattgttct tcaaccaggc tgtgccccca ggtatcactc aacatattga aatccggcag
    41701 acgaatcatc atcacgatcc cgtgggtacc tactttctct tgatcttcca gtaacgttgc
    41761 taactgatta tcgaaaaaga gtcggttatt gaggccggtt ttcatgtcct gggcggcata
    41821 agagcggatc agcgtatcaa gacggctgtg ttgttcgcgt gcgttctgaa tttcacaaag
    41881 cagcgtatcc agcgcactgc tggttctggg cggccattca tagatggttc ccaacacatt
    41941 agagccacgc tcaccgttta agatacgagt agcccgggtt tccagcaatt cttgcccggc
    42001 aagttgccgt tgtaaccagc gtaccgccag gaagagcata agaatgataa agccaatcgc
    42061 ccccgtgagc ggcgcggtgg tcattaaaga atggaaatag ttgcccatcg gatcctgata
    42121 aaccagacgc agcgacatcc ccggatgctt tatcaacgga acgctcagtt cacgaaacag
    42181 atcgttggtg ccaaccggac gataactacc atttctggcc agggtataaa cctgcttatc
    42241 accatggagc aggtctacac gaacgatatc tgccgacatc attaattcgg taatttgtgg
    42301 ccttaatgtg ctgaagtcat tcgacagtag gtgggtatca atcgccgtcg ccaccgcctg
    42361 aacacgatga ctaaacttat actgaatggc gttgtagaaa cttagcgaac agcccagcaa
    42421 agtcacaaaa attgttaacc cggtgagcag cgtgacaaag gccgaaaatt tcgtcgttaa
    42481 tctcatcctt gtgttaactc cgatagtgag gaagcgggca tactagcaaa tcagatttat
    42541 ctcgcaattt attgcgcttc atcggctttg cttttccatt agcgagtata gtcttcagaa
    42601 attattttcc aatccatcat gcacatgagg accacttatg caggcgttac ttttagaaca
    42661 gcaagacggc aaaactctcg catcagtaca gactctggac gaaagtcgcc tgccggaagg
    42721 cgatgtcacg gttgatgttc actggtcgag cctgaactac aaagatgcgc tggcgattac
    42781 cggtaaggga aaaatcatcc gtaattttcc gatgattcct gggatcgatt ttgccggaac
    42841 tgtacgcacc agcgaagatc cgcgttttca tgccggtcag gaggtgttac tcactggctg
    42901 gggcgttggt gaaaaccact ggggtgggct ggcggaacag gcgcgagtga aaggtgactg
    42961 gctggttgcc atgccgcaag ggctggacgc gcgtaaagca atgattatcg gtactgccgg
    43021 ttttaccgcc atgctgtgtg tgatggcgct ggaagatgcc ggtgttcgcc cgcaggatgg
    43081 ggagattgtc gtgacgggtg ccagtggtgg cgtcggcagt accgccgtgg cgctgctgca
    43141 taagttgggt tatcaggtcg ttgctgtttc cggtcgcgaa agtacccatg aatatctgaa
    43201 aagtttaggt gccagccgta ttcttcctcg cgatgagttt gccgaatccc gtcctctgga
    43261 aaaacaagtc tgggctgggg caattgacac cgttggcgac aaagtgctgg caaaagtgct
    43321 ggcgcaaatg aattacggcg gctgcgtggc ggcctgtggt ctggcgggtg gttttactct
    43381 gccaaccacg gtcatgccat ttattctgcg taatgtccgt ttgcaagggg tggattcagt
    43441 aatgacgcca ccagcacgcc gtgcacaagc ctggcagcga ctggtcaccg atttaccgga
    43501 atcattctat acccaggcgg caaaagagat atctctggca gaggcaccga agtttgccga
    43561 ggccatcatt aataaccaga tccagggtcg cacgctggtg aaggttaact aaccatttag
    43621 cagggaataa taagagaggg aactcatttt gaaatcatta ttcaatcagt taacgggaaa
    43681 agcggttagc cggacagctt tcgtcgaaca tcttggttat gaagttgtac aacatcatcc
    43741 aaactggaaa gtcatgattt cgactgacca taaattgatg cgcattgatg ctccaccaaa
    43801 cagccattat tgatacgcct ccgtcgcctg ttaggtttat ggtgctttgc cttggcgacg
    43861 ctacgcttaa tctgttactg atttctggta ccatgggggg aataatctga ttttatttga
    43921 ttacaaatta accacttaaa cctattgaat gcagagcatt gtcagtcggt taattttgcg
    43981 tgctttagca ttcacatctt tccggacgat gcagtgaaaa ttgggtaatc cccagcaacc
    44041 gctgcgtaat gtcgtctatc ttgtcgcgat cctggcatcc ctacattatt tgtggtctgt
    44101 gaagattatc tcattgcagc ccccatcttc gcagggctgg ctttacagcg tttcacctta
    44161 cgttataaga agttccgtcg atgatggcgc taatttcgtg aattgtgcgg cttgttgcaa
    44221 attacacggt gttgaaggtt atttacatgt tagctgttga ttatcttccc tgataagacc
    44281 agtatttagc tgccaattgc tacgaaatcg ttataatgtg cgacctcgtc ctccctgacg
    44341 cagtttttgc actgcggaaa aggtgacatt ggcgcaacga aggtatattt tgttttttgc
    44401 cggaggatag cagcagatcg ctgcacaatg tccgtcaagt ctaacattga cactctgggg
    44461 caaaatagac cggcgtcccg gcctgctgga atttatcgct atgcatacag ctgtcggggc
    44521 atacgcttta cagacggcgg tgaaacgcct gtcacaatca cactaaacaa agagtacgga
    44581 acccactcat ggatattcgt aagattaaaa aactgatcga gctggttgaa gaatcaggca
    44641 tctccgaact ggaaatttct gaaggtgaag agtcagtacg cattagccgt gcagctcctg
    44701 ccgcaagttt ccctgtgatg caacaagctt acgctgcacc tatgatgcag cagccagctc
    44761 aatctaacgc agccgctccg gcgaccgttc cttccatgga agcgccagca gcagcggaaa
    44821 tcagtggtca catcgtacgt tccccgatgg ttggtacttt ctaccgcacc ccaagcccgg
    44881 acgcaaaagc gttcatcgaa gtgggtcaga aagtaaacgt gggcgatacc ctgtgcatcg
    44941 ttgaagccat gaaaatgatg aaccagatcg aagcggacaa atccggtacc gtgaaagcaa
    45001 ttctggtcga aagtggacaa ccggtagaat ttgacgagcc gctggtcgtc atcgagtaac
    45061 gaggcgaaca tgctggataa aattgttatt gccaaccgcg gcgagattgc attgcgtatt
    45121 cttcgtgcct gtaaagaact gggcatcaag actgtcgctg tgcactccag tgcggatcgc
    45181 gatctaaaac acgtattact ggcagatgaa acggtctgta tcggccctgc tccgtcagta
    45241 aaaagttatc tgaacatccc ggcaatcatc agcgccgctg aaatcaccgg cgcagtagca
    45301 atccatccgg gttacggctt cctctccgag aacgccaatt ttgccgagca ggttgaacgc
    45361 tccggcttta tcttcatcgg cccgaaagca gaaaccattc gcctgatggg cgacaaagta
    45421 tccgcaatcg cggcgatgaa aaaagcaggc gttccttgcg taccgggttc tgacggcccg
    45481 ctgggcgacg atatggataa aaaccgcgcc attgctaaac gcattggtta tccggtgatt
    45541 atcaaagcct ccggcggcgg cggtggtcgc ggtatgcgcg tagtgcgcag cgacgctgaa
    45601 ctggcacaat ccatctccat gacccgtgcg gaagcgaaag cagctttcag caacgatatg
    45661 gtttacatgg agaaatacct ggaaaatcct cgccacgtcg agattcaggt actggctgac
    45721 ggtcagggca acgctatcta tctggcggaa cgtgactgct ccatgcagcg ccgccaccag
    45781 aaagtggtcg aagaagcacc ggctccgggc attaccccgg aactgcgtcg ctacatcggc
    45841 gaacgttgcg ctaaagcgtg tgttgatatc ggctatcgcg gtgcaggtac tttcgagttc
    45901 ctgttcgaaa acggcgagtt ctatttcatc gaaatgaaca cccgtattca ggtagaacac
    45961 ccggttactg aaatgatcac cggcgttgac ctgatcaaag aacagctgcg tatcgctgcc
    46021 ggtcaaccgc tgtcgatcaa gcaagaagaa gttcacgttc gcggccatgc ggtggaatgc
    46081 cgtatcaacg ccgaagatcc gaacaccttc ctgccaagtc cgggcaaaat cacccgtttc
    46141 cacgcacctg gtggttttgg cgtacgttgg gaatctcata tctacgcggg ctacaccgta
    46201 ccgccgtact atgactcaat gatcggtaag ctgatttgct acggtgaaaa ccgtgacgtg
    46261 gcgattgctc gcatgaagaa tgcgctgcag gagctgatca tcgacggtat caaaaccaac
    46321 gttgatctgc agatccgcat catgaatgac gagaacttcc agcatggtgg cactaacatc
    46381 cactatctgg agaaaaaact cggtcttcag gaaaaataat ttgtgacgcg cggtgttttc
    46441 atcgcgctta gcaaagaacg taatcaacgc cgggcctgtt aatgctaccc ggcgttttta
    46501 ttgccgttaa ctaacggtag cctgcaattt ccgctttcaa cgcgctaatt tcagcatcgc
    46561 catcaacaat tcccagctca aagcagtatt tctttgtttc ccctggctca ataaagggca
    46621 gacgcccctg cgctcgttct ttatcacgac cgtcaggaaa actattactg acctccagtc
    46681 ccataacata ttcacccgcg cctaaatttt tccactggat aaagttgggt agctgcatgg
    46741 tgtcgaattt ctcgtaaatt ccccacccca gttcggcgtt caccagcgca actttactca
    46801 tcccctgact gtcgctattc aacgtgagat agtaaacctg ctcgtcaaaa ccgggctgtg
    46861 gggtacaaat ctccagatga ctggttaacc cttccgccgc atgcggagtt cgtggcgtta
    46921 tgcttttagc cgacagcaag atttctgcct gtggcgataa taaaggccag ccgtaattaa
    46981 agtgataaag aatttgcagc ggctggcggg tgaaaccatg attagtcacc ttgtcttcaa
    47041 tgcgcattac attttcgcca taacggcagc gaatggtcct ttccagcgtc agattttcac
    47101 cgaacaatcg tgtttcccgt actttgccat tgatgacaaa ttcaatgctg tcgtcggtcc
    47161 gttctgtgcg ataccccacc tcttctgctg gagtcgcagc caaacgcccg tgtaacccca
    47221 gcgtttctcc ttcatcctca cagggtgtgc caatgtagct aagtccgcag gtagtcagta
    47281 accccgcgta aaagctacgt aaaaacccgt tgccctgaga ctcaaaaaaa gcgggggcga
    47341 caacaccgtt gggggtgata aaagagagcg cagtgtcctt gtagctggcc catgcaatat
    47401 ccagcgcgcg atcttttacc accgtaaatg ccagtcccgc accagtacgg acatcaaacg
    47461 cttctgtacc ctttgctctg ccactacgta actcatagtg tttaattccg gcaacctgcg
    47521 agagatcgcc aatccacgac caaatttcgt ttttcattgt gctgcttccc gaatggacat
    47581 gtcatggcgc tggatgaacg tttcgatttc cataaggcga gacgttccct ccattgggcc
    47641 acgtcgggtt accgccagtg caccgcaggc gttggcatat tgtaatgccc gatgggcgtc
    47701 aaaccctagc tggcggcagg caatccacgc gccaccaaag cagtctcctg caccggtcgg
    47761 gtcaacttct tccaccggat agctctcaac atgaaactgc tcattcgcgg agtagtaact
    47821 ggctccttga ttgccgcgct tcacaatcac ctctttaaca ccttcttcaa gaaaaccagc
    47881 gattgcacgc tccggcgtcg agtgtggcga caagagcaac acttccccct cactgggcat
    47941 atagatatcc gttaactcaa gaacaaagtg gagggcatcg cgcatttctg gaatatcaag
    48001 catttcttta cgaatattcg ggtcgaaaga aataacgcca ccatttgctt taacgatggt
    48061 tactgctttt tttactgcgt ctaccatatg gaatgaaaac agggatgaac ccataatatg
    48121 aaaatgggta caatccttca gaatattttc atcaacatgc tgtgccgata atttaccgca
    48181 agcggcattc ttgatattaa aaataaaatc gcgatcgcca gagttatgat aagtaacaaa
    48241 ggcactaccg gtggcttcca gaggtaagac tgaaatcccc ctgatgtcca caccgtcagc
    48301 agccagacga tgtatattaa tatcaccaaa gccatcattc cccacgcagc taatgatgcc
    48361 gcacggaacg ccaagacgtg tcacctggtc gataaaaata gcgggcgcac cactgggata
    48421 agggccgttc cagatacctg gttgatcaaa tggctggccg attttactcg ccataatttc
    48481 aaccagaatt tctccaattg tgaagacctt actcatatga ttaattcctt gaaatgatta
    48541 gctgcgtttt cttttatttc ttacgtcaaa ataaacggct acaagaatga ctaatccttt
    48601 aaccaccatc tggtaaaaat aaggaacatt cattaagttc atgccattat taataacgcc
    48661 gatggttaat gcgccgatca ccgtccccac cacggttcca tagccgccgt tcaggctggt
    48721 gcctcccagt acagctgcgg caatagcatc cagttcgtag ctcaacgcgg aattcggttg
    48781 cccggaatag aggcgtgagg caaggatcat cccgctgata cctgccagca cggctgtaat
    48841 cataaagact ttaattttca agcgggtgac atttatccct gaataaattg ccgcttcttt
    48901 attaccacca gtgatataaa tttttcgtcc aaaggttgtt ttagtaagaa tgaagtggtt
    48961 tatcagcaat aagatgatta atatccatat aggaataggt atatagagaa attctccatt
    49021 ccccagcgcc agaaaggcat catctttaat catgatgggc ataccatcgg tcactatata
    49081 agcgatacca cggaagatcc ccatagtagc aacggtgaca ataaacgaag ggatccccgc
    49141 tatagccgtc aagccaccat ttatcatccc cagagccagt gctgcaataa tggataatgg
    49201 gaccaataaa acaaatggaa ttccccatga agccccaagc gcagcaaatg tgccaatcaa
    49261 tgcaatggtt gaaccgaccg ataaatcaat atcgccaagc aaaagcacat aagtcattcc
    49321 ataggcggta attgcaatta tcgaaacctg aagaataata ttagtaatgt tattggcggt
    49381 aaaaaaactg tcattaataa aactgaacag aatgattaac accaccattc cactgaggat
    49441 accaccatat tgcctgaaga cttttttaaa attatttgca atgggaattc ccgaaggttt
    49501 cggactggca agagttttct ctgtcattta acgtactcct gttgcagcgg tcattacctg
    49561 tgtctgcgtt aaattttcac atgaataaat atcggcaata gttttattac gcattaccac
    49621 cagacgatcg ctaagtgcca tgacttctgg cagttcagag gacaccagaa taattgctgt
    49681 ccctgccgca gccagttgac gtatcacgtt atagatttca aattttgcgc cgacatccac
    49741 tccgcgcgtt ggctcatcga gcaataaaat acgcggagtt ttctccagcc acttcgataa
    49801 cacgattttc tgttgattac cgccgctcag tgctcccact gcctgatgca cagaactcac
    49861 tttagtgttc attctggcaa ttgattgcag cgtcttcgcc tcttcttgtc ggtgattgat
    49921 gagtcccatc cgcgaagcgt tatattgaaa cgccacatgg tgcgtgttca tattgacgtc
    49981 gtgcatcagc actaaccctt cttccttgcg gttttcggtc acaaaagcaa tgccatgatc
    50041 aatagcctgt ttgggattag cgatcctgac ttccttacca tcaatcaaca cagtcccgtg
    50101 atacgaaacg aggccaaata gcgccttcat cacatcggaa cgcccggccc ccaccaggcc
    50161 aaaaaatccg aggacttccc ccggacgcac agcgaaactg acctctttaa aaagcgaagg
    50221 atgggaaaga ttttttactt ccagttttgc aggaacattt tcatccggtt tttccccaag
    50281 acgtgctggc caaatatttt tcatttcccg accaaccatt tgggcaatca agtgctggat
    50341 atcactgttt ttcttttcat gcgtagcgat atactcaccg tcgcggatca ccgaaatatc
    50401 atctgaaatc cgcataattt catccatgcg atgagagata taaataaccg cacagcctcg
    50461 ctgctttaat ttttcaataa tgttaaacag gatctccgct tcattatcac ttagcgaaga
    50521 tgtcggttca tccataatca cgacatccgc tgcatagctt aaggctttag caatttctac
    50581 cagttgccta tgtgccatcg acatattgcc gaccatttcc agagggtcta gtgggatgcc
    50641 cagttccgcg aggaggttct ggcaatctgc gagcattttt ttatcgttaa tgatgccaaa
    50701 acgtcgcggt tcattattgg cataaatatt ttccgccacg gtcatattat tactcaggct
    50761 cagttcctga aaaataatcg caatccctaa ctggcgagaa tgctgcggat tattaatggt
    50821 gatggtttca ccacgtagtg ttatcgttcc ctgggttggc ggataaacac cggccagtat
    50881 tttcattaat gtcgatttac cggcaccatt ctcgcctaat aaagtatgca cccgcccttt
    50941 acgtaaagag agtgtaatat cttttaatgc ctgaacatga ccaaatgtct tcgcaatatg
    51001 cgaaacatca agaataacat ccgtcataat gacctcggtg tcacaacaaa acgccaataa
    51061 cgttttgttg tgaggtgaag atatttacta tttacctgta taaacgccgg gttgtaccgg
    51121 gatcattttt tctaccggtt taccattgag gtgatcaaca gcggcatcaa tggctttagc
    51181 acccatttga tctggatatt gccgaatcac ggccgcaaac gttttttcac tgtcaacggc
    51241 atcacgcgct tctttcatgc cgtcaaaacc aatgattttg atgttgtcgt tatgcgcaga
    51301 ttttgctgcg ataaccgctg ccagcgccgc atcatcacca aagccaaaca gaccattcag
    51361 gttagcattt gcctgcataa tgttttgcgc agtcgttaac gcttcagctc gcgtaatacc
    51421 aggctgttca gcaacaattt taatatccgg tgtatcgctt aaccctttct taaaaccatc
    51481 aacgcgcgca accaccgatt gtagtgccgg ataagaaata atggctacag tacctttacc
    51541 actcaaaagt ttacccatta acttgcctgc ttcaacgcct cccgcatagt tatcggtcgc
    51601 aacatgcgat acgaccggaa cgccttccgc agcgacgtca acggtgataa cgggaatacc
    51661 ggccttatcg gctttaatta tcgctgcctg gacgcctttc gaatcgaccg gagagataat
    51721 aatggcatcc acttttttag taataaaatc ctcaacatca gaaagttgtt tgtttaaatc
    51781 ctgattggca atagagacac ttaaattgac attgtctttt tttgcctctt ctttcatggc
    51841 attcgcaaga tcaatataga aaggatgttg ttgtgttaat aatgacgcac caattttata
    51901 ctcttttgcc aacgaacttt gcgagaacaa tgccaggctc accaacatag ctgaaccaag
    51961 taatttaata tttttcataa acaatcctca ttatttttgt agggtacaac gtcttaaatt
    52021 tttccttcac taccacaaac gccaataata cgagttacga cttctttcat ggcggccttt
    52081 gcgggctgca tatagtgacg tggatcattt gccgcaggat tgttgtagaa atatcctttt
    52141 aacgcatcgg caaacgcaat tttcaattct gtcgcgacat tcactttaca aataccgcga
    52201 cgaatacagt gctgaacgtc ctgttccgat aagcccgaag caccatgcaa caccagcgga
    52261 atctccactc gctgacgaat ctgttccagc cgcacaaaat ccagtcgtgg ttcatgcgca
    52321 tataaaccat gtgctgtgcc gattgctacc gccagggagt caatttgggt acgttgaaca
    52381 aactctgtag ctgcggctgg cgaggtataa gcggaatctt tttcatccac ccgcagatcg
    52441 tcctcctggc cgccaagacg ccctagctcg gcctcaacgc taacatcaaa gcgatggcaa
    52501 aaggtggtaa cttcttgcac tcgcgcaatg ttgtcttcaa atggcaaatg ggagccatca
    52561 atcatgacag aacggatccc tgcgcgaacc ttgttaaaaa tgtcatcact ctcttcatga
    52621 tggtcgagat gcaggactaa cggcaggttg tactcgcgag ccagcgattg tactaacgaa
    52681 attaaacttc ccacgccacc ataacgatat gtaccgggtg ttcccgccag cataacggga
    52741 gagcgaagtt gtgcagcgct ctcaacaact acctgtaaag tttcaaggtt atgaatgttg
    52801 aaagcaggga cggcatatcc ctctgactgg gcttttttca gcatgttttt gcttgaaata
    52861 atgtacatcg cagctcctgt tatttgtcgt tcgccttaca aaatgaagaa agagaatctt
    52921 cactttcatt ttgaaagcaa actagcacag caaaagcagc aaaaagcgtg atgcatgtcg
    52981 aacatcatca aaataactta caaaaaataa cttaatttat ttttcac
//
LOCUS       DAPOXO010000027        52003 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPOXO010000027 DAPOXO010000000
VERSION     DAPOXO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 52003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52003
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.027"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..820)
                     /gene="rarD"
                     /locus_tag="ROH59_001936"
     CDS             complement(<1..820)
                     /gene="rarD"
                     /locus_tag="ROH59_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HDX4804419.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTF"
     gene            complement(872..1339)
                     /locus_tag="ROH59_001937"
     CDS             complement(872..1339)
                     /locus_tag="ROH59_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HDX4804420.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            1504..2373
                     /gene="pldA"
                     /locus_tag="ROH59_001938"
     CDS             1504..2373
                     /gene="pldA"
                     /locus_tag="ROH59_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HDX4804421.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYIIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSDESSPFRETNYEPQLFLGFATDYNFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            2498..4327
                     /gene="recQ"
                     /locus_tag="ROH59_001939"
     CDS             2498..4327
                     /gene="recQ"
                     /locus_tag="ROH59_001939"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDX4804422.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLEVMTGCRTGQISLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            4392..5012
                     /gene="rhtC"
                     /locus_tag="ROH59_001940"
     CDS             4392..5012
                     /gene="rhtC"
                     /locus_tag="ROH59_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709629.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HDX4804423.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEVVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVET
                     LAWFTVVASLFALPQMRCGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(5050..5910)
                     /locus_tag="ROH59_001941"
     CDS             complement(5050..5910)
                     /locus_tag="ROH59_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDX4804424.1"
                     /translation="MTEATTPHDAIFKAFLSRPETARDFIEIHLPPSLVKLCNLDTLH
                     LESSSFVEENLRQYYNDVLYSVETTKGCGYIYVLIEHQSSPDENMAFRMLRYAIATMQ
                     RHLEAGHDYLPLVIPILFYQGKRSPYPWSTNWLDGFPDPDIARDLYFHAFPLVDITLI
                     PDDEIMQHRSMAAFTLVQKHIRQRDMTTLLDKLSRLMILGQMSGQQIRMLINYMALVG
                     EAQDVRTLVHGLAQRVPQQGEELMTLAEELRRDALLNVAKAMLQRGFDLQLIMEMTGL
                     SQEDLYQLQS"
     gene            complement(6069..6689)
                     /gene="rhtB"
                     /locus_tag="ROH59_001942"
     CDS             complement(6069..6689)
                     /gene="rhtB"
                     /locus_tag="ROH59_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HDX4804425.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            6800..7822
                     /gene="pldB"
                     /locus_tag="ROH59_001943"
     CDS             6800..7822
                     /gene="pldB"
                     /locus_tag="ROH59_001943"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HDX4804426.1"
                     /translation="MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHSGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            7830..8630
                     /gene="yigL"
                     /locus_tag="ROH59_001944"
     CDS             7830..8630
                     /gene="yigL"
                     /locus_tag="ROH59_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HDX4804427.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFNYALYEPGLLEPEGVSKVFFTCDSHEKLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLQDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNAEDAVPHYLRKLYLS"
     gene            8706..9605
                     /gene="bioP"
                     /locus_tag="ROH59_001945"
     CDS             8706..9605
                     /gene="bioP"
                     /locus_tag="ROH59_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HDX4804428.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALNE"
     gene            complement(9493..10446)
                     /gene="metR"
                     /locus_tag="ROH59_001946"
     CDS             complement(9493..10446)
                     /gene="metR"
                     /locus_tag="ROH59_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HDX4804429.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     ITEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            10564..12825
                     /gene="metE"
                     /locus_tag="ROH59_001947"
     CDS             10564..12825
                     /gene="metE"
                     /locus_tag="ROH59_001947"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDX4804430.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPQRHQNNDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHKVKPV
                     LLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAV
                     EKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NIDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRRG"
     gene            13164..13721
                     /locus_tag="ROH59_001948"
     CDS             13164..13721
                     /locus_tag="ROH59_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDX4804431.1"
                     /translation="MDAKLYITEIINELTFVKDSIREDDCTKLIDTIQQSQRVFCYGL
                     GRAGFSMKAFTMRLMHMGKEVYFLTETITPNFGPGDLFIVSSASGETAQLVALAKKAR
                     QLGGAVAVLTTNRHATITEFVDVIVQINAPSKNQKDSVFRSAQPMASLYEQALLVIAD
                     ALVMKMAAESGAPESELFKRHANLE"
     gene            13763..15271
                     /locus_tag="ROH59_001949"
     CDS             13763..15271
                     /locus_tag="ROH59_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDX4804432.1"
                     /translation="MSKKITSLFNFKKLQKFSSALMLPIAILPAAGLILAIGISFNIE
                     LLANCGGLIFANLPLLFCVGIVIGLTGDGSSSLSAIISYMIMNATMGTQLGITAESVA
                     ASNGDYAMILGVPTLQTGVFGGLIVAIFVYLLYTRFHNIELPQFLGFFGGKRFVPIIT
                     AVAAIIVGYLLPWLWIPVQKGLASLSTLVTSGHNANFAAFIYAVGERSLIPFGLHHIW
                     NVPFYYNFGDYMTKSGQLVTGDIPVFFAQLRDGAPLTAGLFMTGRFPIMMFALPAAAL
                     AMYQEAKPERKALIKGLLLSGALTTFVTGITEPLEYAFLFAAPVLYIIHIFLYATSFV
                     LMNILNVHIGHPFAGGLIDFVLNGVMPNRTPWYLVFLAGAGYAAIYYTVFRVLIRKLN
                     LKTPGREDEEIAVATTLAREERPYQIIEAVGGFDNIEDVDACATRLRLALVDDKKVNE
                     KRLKELGAAGLVKLGDGGVQVIFGGKSQILRDEIKTVMSRPRPTEMTVACAN"
     gene            15322..17319
                     /gene="tkt"
                     /locus_tag="ROH59_001950"
     CDS             15322..17319
                     /gene="tkt"
                     /locus_tag="ROH59_001950"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDX4804433.1"
                     /translation="MNSQLLANAIRMLSVDAIQKANSGHPGAPMGMADIAEVVWRRHL
                     RHNPKNPQWFNRDRYVQSNGHGSMLIYALLHLTGYDLSMDDIRDFRQLHSRTPGHPEY
                     GYTPGVETTTGPLGQGVANAVGMAIAEKALAAEFNKPGFNIVDHHTWLFLGDGCLMEG
                     ISHEACGLAGTLKLGNLIAIWDDNGISIDGHVEGWFAEDTAARFRAYGWHVIEGVDGH
                     DPEAVDAAVREAKSVTDKPSLLCCKTIIGFGSPNKANSHDCHGSALGADEVALVRERL
                     QWPYAPFEIPGEIYAEWDATEKGAQVQQEWDALFADYAKQWPELAAEFTRRMKGDLPA
                     GWVENMQKYVHDLQSHPAALATRQVSQKCLNHFADMLPELMGGSADLSPSNLTRHQKS
                     VDFTGENPAGNYISYGVREFGMSAIMNGLALHGGFIPYGGTFLMFMEYARNALRMAAL
                     MKIRSVFVYTHDTIGLGEDGPTHQPVEQLASLRLTPNMETWRGCDQVEVAVAWQQAIE
                     RKDGPTSLVLTRQPLAQQPRTAAQLAEIARGGYVLSDCDGQPEMILISAGSEIELVVS
                     AAKALTEEGRKVRVVSMPCTERFDNQDAAYKESVLPKAVRKRLAVEASIAGFWERYVG
                     LDGKVIGMTSFGESAPANVLFKHFGFTPENVLAQARELLNS"
     gene            complement(17349..18194)
                     /locus_tag="ROH59_001951"
     CDS             complement(17349..18194)
                     /locus_tag="ROH59_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDX4804434.1"
                     /translation="MNNITVKSLIQSNYPTLHQAEKKVADYILSHAHEVVNYSVTELS
                     EKSHASEATIVRTCKKLGYQGYYHLKIALAKEVINPDNSYPENTDFSDITSLATFLLK
                     KQAEDLIQSTQFFNADVLESILKLLANCDTIFFFAAGNSNPLAVYSAYKFSQLGLKTV
                     VHVSPEMQINAAYSMGKRDLAIGISNSGSTNLMVDIFKVVKERGAKSVCITNYIKSPL
                     SKLSTHQLNTAVSDKIFFEAFDSTRVPAMGVIDMLVLLFMYKNKAHYEKYRTREEFLG
                     SRFKG"
     gene            complement(18394..19299)
                     /locus_tag="ROH59_001952"
     CDS             complement(18394..19299)
                     /locus_tag="ROH59_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4804435.1"
                     /translation="MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEES
                     LGVELFIRKGRYIELSPAGSYFIEHSKTILGDLEALKRNTVLIHDGIERELTIAVNNI
                     IPGDLLVAFIRDFERQFTSTTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGII
                     SEPVGQMEWDFVVSPLHPLAAKRHPLENSELRHYPAVCIRDTSVNFPPMQAWLLEGQK
                     PIFVPDFATAIALIEQNVGIGYIPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSD
                     GMGKACQWCIEYLRNQQLMTRFVFN"
     gene            complement(19377..20600)
                     /locus_tag="ROH59_001953"
     CDS             complement(19377..20600)
                     /locus_tag="ROH59_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDX4804436.1"
                     /translation="MRKKEENLNTASGLRIAMILLGIAVTPVLLSSSSLGNQLSSGSL
                     ISVVLLGGVILTLLSAITISVGEKARLPTYGIVKYSFGEKGAIAINILMAISLFGWIA
                     VTANMFGHSVHDLLAQHGLEVPLALLVAAGCVIFVASTAFGFAVLGKIAQVAVPVIAL
                     VLCYILYVATHTEVAVPAAIVEMNTGVAVSTVVGTIIVLVATLPDFGSFVHNRKHALI
                     AAGVTFLVAYPLLYWAGATPSAISGQGSLLGAMAVFGAVLPAALLLIFACVTGNAGNM
                     FQGTLVVSTLLTRFPKWQITVALGILSAIVGSMDIMAWFIPFLLFLGIATPPVAGIYI
                     ADFFLYRRNGYQESVLAQESQIKVLTFAAWIIGAAVGFMTVKGLFTLTTIPSVDSILV
                     ACIAYAILSRASQHR"
     gene            complement(20626..21015)
                     /locus_tag="ROH59_001954"
     CDS             complement(20626..21015)
                     /locus_tag="ROH59_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA amidotransferase"
                     /protein_id="HDX4804437.1"
                     /translation="MTTTLLAVNGTLMRGLELNPNMQKAGGIFVREDRTDAHYRLWSI
                     NDRHPGMIRVNEGGTHVDVEIWQLPLASFAALLMSEPAGLAIGKIKLADGSEVLGVLA
                     ENWLTEGQREITELGSWRKYTGHFHTV"
     gene            complement(21032..21988)
                     /gene="arcC"
                     /locus_tag="ROH59_001955"
     CDS             complement(21032..21988)
                     /gene="arcC"
                     /locus_tag="ROH59_001955"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDX4804438.1"
                     /translation="MVKPLAVVAVGGNALIQDEQRNSIPDQYVAVMESVQHIVDMVEA
                     GWDLVLTHGNGPQVGFILRRSELASNEVSPVPLDYAVGDTQGAIGYMFQKALHNELAR
                     RGINKPVIALVTQTRVSPHDDAFASPSKPIGAFLDEATAQQRQQQLGWTLMEDAGRGW
                     RRTVPSPAPLEIIEHDTIAHLVRQGYLVIACGGGGIPVVRDGQQLKGVEAVIDKDLAS
                     ALLASQLGADLLVIPTGVEKVAINFGTPQQQWLDAISVAEAQTLLREGQFGVGSMQPK
                     VEAIVDFINASQQQGKQASGLITSPQTIKAALAHQSGTWITL"
     gene            complement(21981..23405)
                     /locus_tag="ROH59_001956"
     CDS             complement(21981..23405)
                     /locus_tag="ROH59_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDX4804439.1"
                     /translation="MNTLFNQPLKVVNAGLHSFADNIQHAGGSAIALNWQPPAQGDID
                     AGLDLASLLRHPLVENANQIAMARYLEAQPVLVDVMLAKEAIPAMAEQKRILHSGPPI
                     AWEEMCGPVKGAIIGAMLYEGWATSQQDAENQINAGEIDLAPCHHYHAVGPMAGIISP
                     SMPLWVVENKTNGHRTFSNFNEGLGKVLRFGANNDEVLNRLAWMRDELTPAMKAAIAQ
                     HGELELKPLMAQALHMGDEVHNRNAAATGLLIKRLLPALLACSLPQEHIQRVVAFITG
                     NDHFFLNLSMAACKAMMDAAANVPFSSMVTVMARNGVNFGIRISGTGDRWFQAPANAV
                     EGLFFPGFGVDDAAADLGDSAITETAGVGGFAMASSPAIVKFVGGTPADATNNSRRMQ
                     AITLGGNPAFTLPALNFAPTAAGIDARKVTDRGILPVINTGIAHKQAGVGQIGAGITT
                     APMACFVAAVRALAEIVAKENHHG"
     gene            complement(23402..24961)
                     /gene="fdrA"
                     /locus_tag="ROH59_001957"
     CDS             complement(23402..24961)
                     /gene="fdrA"
                     /locus_tag="ROH59_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDX4804440.1"
                     /translation="MKVKYKVFSNLYQDSVSLMQISAQISKLPGIQQASVVMGTPNNL
                     EQLRDAGLGNEINASPNDLVIAVMGEEDICNEALILAQQRLTSKPDDETDSGIKTPEK
                     VSLEMALEAEPEANLALISVPGDYAAAEAIKALNLGMNVMMFSDNVSIVQEKSIKTLA
                     RERQRIVMGPDCGTAIVNGIPLGFANVVKRGAIGVIGASGTGLQEVTCRIDQLGAGIS
                     QALGTGGHDLSKEIGGISMLFALDALAQDDETRVIVLISKPPSPIVARTILERAEACG
                     KPVVVNFLGANPHDLARPNITAATTLASAADIAVALLNAQPLPAVETDVPCDDLTMLQ
                     NACQRLPAHRQAIRGVFAGGTFCYEAQLICQQKGFSAASNTPVAGNRALANIWQSEDH
                     TLIDMGDDDFTRGKPHPMIDPTLRNQRLLNELNDSHTAVVLFDLVLGYGASTTPASEL
                     LDQLSHIDMNNAPLLIAHVCGTEADPQIRSQQISALQNAGVIIASSNAQAALWASTVA
                     QTQLQKKGLNA"
     gene            complement(25056..25916)
                     /locus_tag="ROH59_001958"
     CDS             complement(25056..25916)
                     /locus_tag="ROH59_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001374637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDX4804441.1"
                     /translation="MVQVTLCASSLGYLFPQDETQDLRLHSAFKHAVNLYSDAGTFIT
                     LLCAQTYLNLPDAARVWLPECWDWRREIAHSDPIQLTPGLLRTPRFCVALDNATLWQS
                     PFVGGMLTLEAFPLVFQHYPTMASQRLLFCLEHNVQSTLHLPDSLTHQGLAIMEHPDA
                     LERQVPQLIGFGKGLTPDGDDYLLGYLAALWLWQLPAPLADHQYRLQQAIDQHAHNTT
                     DISRHYLERALQGHFSEPICQLLAQLVGSASAMTIASCAEQVMQFGATSGVDCLAGML
                     HGFRTLNTMN"
     gene            complement(25922..26590)
                     /locus_tag="ROH59_001959"
     CDS             complement(25922..26590)
                     /locus_tag="ROH59_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDX4804442.1"
                     /translation="MTQSIFQAQPFELPFDPRTTALVMIDMQRDFVEAGGFGEALGND
                     VSRVRTAIAPCTEVLAAARQKGIMVIHTREGHRADLSDCPPAKLTRGGKTFIGEPGPM
                     GRILVRGEAGHDIIPELYPVAGEPVIDKPGKGAFYQTDLHLILQNHGIKTLIVCGVTT
                     EVCVTTTVREANDRGYECIIPEDCVGSYFPEFQKYALEMIKAQGAIFGWVTDSKAIIA
                     GLEG"
     gene            complement(26847..27656)
                     /locus_tag="ROH59_001960"
     CDS             complement(26847..27656)
                     /locus_tag="ROH59_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDX4804443.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLGGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPVLGLYGGQDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAEHAFNADYRPSYHAESAKDGWQRMLEWFTQYGVKK"
     gene            27918..28682
                     /gene="udp"
                     /locus_tag="ROH59_001961"
     CDS             27918..28682
                     /gene="udp"
                     /locus_tag="ROH59_001961"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001593007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HDX4804444.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLLK"
     gene            complement(28717..30207)
                     /locus_tag="ROH59_001962"
     CDS             complement(28717..30207)
                     /locus_tag="ROH59_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HDX4804445.1"
                     /translation="MFESELLTQGFSTLLNNPQALLFATFGVMLGIVIGALPGLTATM
                     GVAILLPFTYGMEPVSGLLMICGVFFGGVYGGSITAILLKIPGTPAAAATAIDGYELT
                     KQGKAGLALSAATFSSFSGGTLSIIVLMFLSPVLASWALKFSASESFALATFGLSIIA
                     SISGESLIKGLIAGVGGLLIATIGLDPMGGFPRFTGGFVELMNVPFIPVMIGLFAASE
                     AFRSMEQNQQIRQGAKVAIGSLLLPWQTLRRIALTILRSSGLGVFIGMIPGAGADIAA
                     FVAYNETRRFSKTPENFGKGEIKAVASCEAGANGCTGGALLPMLTLGIPGDAVTAIML
                     GALTLQGMQPGPLMFTDHGDMVYTLFVGMIFCYFMLLVLGLLSLKVIGNVVKIPGNIL
                     TPMILALCVVGTYALNNSLFDVGIMLIAGVVGYFMQKGGYPASPVVLALIMGPMAESN
                     FRRALSLSGGSLDFLYTRPITLALLTLAAFTLLTPIIRKIMRLRRQ"
     gene            complement(30220..30726)
                     /locus_tag="ROH59_001963"
     CDS             complement(30220..30726)
                     /locus_tag="ROH59_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001596577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HDX4804446.1"
                     /translation="MNTKQSVAQLAVPHRKRLSSTMVVALLLCVVAGAVMINAADFPA
                     TAIETDPGASAFPTFYACALIVLAVLLVIRDLLQAKPASCANAQEKPAFRKTATGIAA
                     TAFYIVAMSYCGYLITTPVFLIVIMTLMGYRRWVLTPGIALLLTAILWLLFVEALQVP
                     LPVGTFFE"
     gene            complement(30743..31717)
                     /locus_tag="ROH59_001964"
     CDS             complement(30743..31717)
                     /locus_tag="ROH59_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HDX4804447.1"
                     /translation="MIKHLTLPKKMAAMVLLAGAALSIAPVQAASWPTKQIELVVPYA
                     AGGGTDLVARAFADAAKNHLPVSIGVINKPGGGGAIGLSEIAAARPGGYKIGLGTVEL
                     TTLPSLGMVRFKTSDFKPIARLNADPAAITVRADAPWNSYEEFMTYAKANPGKVRIGN
                     SGTGAIWHLAAAALEDKTGAKFSHVPYDGAAPAITGLLGGHIEAVSVSPGEVINHVKG
                     GKLKTLVVMADERMKTMPDVPTLKEKGVDLSIGTWRGLIVSQKTPQDVVDVLAKAAKE
                     TAEEPAFQDALQKLNLNYAWLDAASFQTQISEQEKYFDELLTRLGLKK"
     gene            complement(31742..32371)
                     /locus_tag="ROH59_001965"
     CDS             complement(31742..32371)
                     /locus_tag="ROH59_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001116470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HDX4804448.1"
                     /translation="MPFNTLLQKTGLVAILRGVKPDEIVAIGEKLYAAGFRLIEIPMN
                     SPEALQSISLLRDALPKDCLVGAGTVLSVEQVVAVKEAGGQIIVMPHCDTAVIRRARA
                     LGMYCAPGVATPTEAFTAIEHGANAIKLFPAEQITPEVTKAWRAVIPQSVPMLPVGGI
                     TPETMARYLSHGANGFGLGSALYHPGMTPEQVYENAVLFMNAWNNLNSN"
     gene            complement(32361..33365)
                     /locus_tag="ROH59_001966"
     CDS             complement(32361..33365)
                     /locus_tag="ROH59_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HDX4804449.1"
                     /translation="MPGAPSFIALDWGTSSLRAWRFGESPNPQEKREFPWGIMKLPSQ
                     AATREDAFHDTFLRVCGDWLAQTPCPVLACGMLGSAQGWQPAAYLPCPVTLEGLAKQL
                     TPVIHQQQTMLHIIPGVIKEGEMPEVMRGEETQIFGAISMEPSLQNAIHQGMPVLIGL
                     PGTHAKWAVVENNTITDFRTFMTGELFDVLSRHSILGATMHPGDELHWDAFTHGLTAA
                     QEHHQTGLLSTLFSTRSRLLTSNLTSSSQGDYLSGLLIGHELCGLASSLLRDLPATTP
                     IALIGSANLNSRYSQAFSHVFPDRQIHAIPNATEQGLWRIAHAAGLLSTNARECTHAI
                     "
     gene            complement(33389..34156)
                     /locus_tag="ROH59_001967"
     CDS             complement(33389..34156)
                     /locus_tag="ROH59_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDX4804450.1"
                     /translation="MAETSSTTAGAQTLLRGLAVLNAVYNGCHDLKSIGEFTGTTRST
                     THRLVTVLVEQRYLRHVPTQGYQLGAKLIEFGARALESTSLYEIAQPVLQRLARYTLD
                     TVHLGIVEGDEVLYLEKINSQRGLEMRSRPGHRMPLAITGIGKALILNRTEEEWRTLF
                     KTCGDETKLGAFIQNMRRYAASGFAFDLEENEPTIRCVAAPVYNARDEIVAAISVAST
                     TTYMSLARLEELAPYVKSCAEEISAELGWGKHVRKDK"
     gene            34373..35800
                     /gene="rmuC"
                     /locus_tag="ROH59_001968"
     CDS             34373..35800
                     /gene="rmuC"
                     /locus_tag="ROH59_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HDX4804451.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYQTQVSIETDTRSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAI
                     GQNLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            35895..36650
                     /gene="ubiE"
                     /locus_tag="ROH59_001969"
     CDS             35895..36650
                     /gene="ubiE"
                     /locus_tag="ROH59_001969"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HDX4804452.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKTMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            36664..37269
                     /gene="ubiJ"
                     /locus_tag="ROH59_001970"
     CDS             36664..37269
                     /gene="ubiJ"
                     /locus_tag="ROH59_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HDX4804453.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLAALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKALRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            37266..38906
                     /gene="ubiB"
                     /locus_tag="ROH59_001971"
     CDS             37266..38906
                     /gene="ubiB"
                     /locus_tag="ROH59_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HDX4804454.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKPLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVATLEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            38985..39254
                     /gene="tatA"
                     /locus_tag="ROH59_001972"
     CDS             38985..39254
                     /gene="tatA"
                     /locus_tag="ROH59_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HDX4804455.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            39258..39773
                     /gene="tatB"
                     /locus_tag="ROH59_001973"
     CDS             39258..39773
                     /gene="tatB"
                     /locus_tag="ROH59_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HDX4804456.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNETVHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            39776..40552
                     /gene="tatC"
                     /locus_tag="ROH59_001974"
     CDS             39776..40552
                     /gene="tatC"
                     /locus_tag="ROH59_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HDX4804457.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIISVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            40594..41376
                     /gene="tatD"
                     /locus_tag="ROH59_001975"
     CDS             40594..41376
                     /gene="tatD"
                     /locus_tag="ROH59_001975"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HDX4804458.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAVTEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAAELNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVACGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNAPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(41373..41861)
                     /gene="rfaH"
                     /locus_tag="ROH59_001976"
     CDS             complement(41373..41861)
                     /gene="rfaH"
                     /locus_tag="ROH59_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HDX4804459.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPSTPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            42028..43521
                     /gene="ubiD"
                     /locus_tag="ROH59_001977"
     CDS             42028..43521
                     /gene="ubiD"
                     /locus_tag="ROH59_001977"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HDX4804460.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            43567..44268
                     /gene="fre"
                     /locus_tag="ROH59_001978"
     CDS             43567..44268
                     /gene="fre"
                     /locus_tag="ROH59_001978"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HDX4804461.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
     gene            complement(44449..45612)
                     /gene="fadA"
                     /locus_tag="ROH59_001979"
     CDS             complement(44449..45612)
                     /gene="fadA"
                     /locus_tag="ROH59_001979"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HDX4804462.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMEHKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(45622..47811)
                     /gene="fadB"
                     /locus_tag="ROH59_001980"
     CDS             complement(45622..47811)
                     /gene="fadB"
                     /locus_tag="ROH59_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HDX4804463.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLIEGAMAILRQAINGDLDWKAKRQPK
                     LEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     DYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDVVVDDLLAKVSQPKRDFSE
                     EEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            48001..49332
                     /gene="pepQ"
                     /locus_tag="ROH59_001981"
     CDS             48001..49332
                     /gene="pepQ"
                     /locus_tag="ROH59_001981"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HDX4804464.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA"
     gene            49332..49946
                     /locus_tag="ROH59_001982"
     CDS             49332..49946
                     /locus_tag="ROH59_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HDX4804465.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITLLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYSQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            49985..51436
                     /gene="trkH"
                     /locus_tag="ROH59_001983"
     CDS             49985..51436
                     /gene="trkH"
                     /locus_tag="ROH59_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HDX4804466.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFSLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            51448..51993
                     /gene="hemG"
                     /locus_tag="ROH59_001984"
     CDS             51448..51993
                     /gene="hemG"
                     /locus_tag="ROH59_001984"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HDX4804467.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTN
                     SYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
BASE COUNT        12346 a        13081 c        13870 g        12706 t
ORIGIN      
        1 cgaaagtcac catcttatcg gcacccggtt tttcaccata aaacgtcaca gccagcagga
       61 acatcagcgt cggaccaatg tactggaaaa agcctaacgt tgagagacgc aggcgtgtcg
      121 cagctgcagt aaaacacaac agtggcacgg tggtgacaat accggcggcg atcagcagta
      181 aattcagcga catcgggttt tgccccatat gactggttga gctgtcggca atagcaaaca
      241 ggtaaatcgc cgccacgggc agcaaccaca tagtttcgat taacatgccg gtttgcgctt
      301 caacagcaat cttcttgcgc accaggccgt agaaagcaaa actaaacgcc agccccagcg
      361 cgatgatcgg cagtgaacca aaagtccaca actgaaccaa cacgccacaa atcgccagaa
      421 tcaccgccag ccattgcatc cggcggaatc gctcgccgag gaaaatcatc cccagcacaa
      481 tgttcaccag tgggttaata aagtaaccaa ggctcgcttc cagcatatgg tgattgttca
      541 ccgcccagat aaacagtagc cagttgccac caatcagcac ggcagagact gccagcataa
      601 aaattttctg tggcgtctga atcagcgttt ttaaatagga ccactggcgg caaatgctca
      661 tcagcaccac cataaagaaa aacgaccaga tcacgcgatg cgtcaggatc tcatcggcgg
      721 gcacgtagta aatcagtttg aagtacgctg gcgcaatacc ccaaataaaa taagcggcaa
      781 gagcgagtaa tacgccctgc cgcgtttgtt ttgcatccat cgggaatact catttttaat
      841 tggtaacagc agtttacctg cttttatgtc ttcaacctac catataggtg gcggtggcac
      901 tggcaatata aagctgttct tcattgtgta attcaacgcg ggcgacggcg actttattgc
      961 ctgcacgcaa caggctactg gtagcagtaa aacgctctcc tctgcctggg cgcagataat
     1021 cgacgcgaag atcaatggtc cccatccgcg atagccgctg gcgtagttca tcttcactga
     1081 tggtttcgtg gcgggttaag gtacttccca cgcacaccag acctgcggcg acatccagcg
     1141 ccgacgcaat gaccccgccg tgtaaaatgc tttgcgccca gttgcccacc atcatcggct
     1201 gatttttaaa ggccagctgt gcgaactctt tttcgtaacg ctccagttcc atccccaatg
     1261 cgcggttaaa tggcatgtga taaacaaaca tctcacccac taatttgagg gcttgttcag
     1321 cggtcagtac ggcagacata acatccttac acttcattag ttaatgaaat gttgatttta
     1381 tgcttattta ttgttggttt ctactttagg aagggataac taacggctat ggagttaagt
     1441 atgtaaaata gcccgcagaa aaatattcac cttatcaata attcgttacg gagaacacga
     1501 gcgatgcgga ctctgcaggg ctggttgttg ccggtgttta tgttgcctat ggcagtatat
     1561 gcacaagagg caacggtgaa agaggtgcat gacgcgccag cggtgcgtgg cagtattatc
     1621 gccaatatgc tgcaggagca tgacaatccg ttcacccttt atccttatga caccaactac
     1681 atcatctaca cccaaaccag cgatctgaat aaagaagcga ttgccagtta cgactgggcg
     1741 gaaaacgcgc gtaaggatga agtaaagttc cagttgagcc tggcgtttcc gctgtggcgt
     1801 gggattttgg ggccaaactc tgtactgggc gcctcctaca cacagaaatc ctggtggcag
     1861 ctttctaata gcgatgagtc atcaccgttt cgtgaaacta actacgaacc gcaattgttc
     1921 ctcggttttg ccacggatta caactttgct ggctggacgc tgcgcgatgt ggaaatgggc
     1981 tacaaccacg actcaaacgg gcgttcagac ccgacttccc gcagctggaa ccgcctttat
     2041 acccgcctga tggcagaaaa cggtaactgg ttggtagagg tgaagccgtg gtatgtggtg
     2101 gggaatacgg acgataaccc ggacatcacc aaatatatgg gttactacca gcttaaaatc
     2161 ggctatcacc tcggtgatgc ggtactgagc gcgaaagggc agtacaactg gaacaccggt
     2221 tacggcggcg cggagttagg cttaagctac ccgatcacca aacatgtgcg cctttatact
     2281 caggtttaca gcggttacgg cgaatcgctc atcgactata acttcaacca gacccgcgtt
     2341 ggtgtgggag ttatgctaaa cgacctgttt tgatgaatgg ttggcaaatc tggaatccag
     2401 catccaggat taccctctca gagactaaaa gcattgcagt ttctcgcgca ggcgctgaaa
     2461 atagcgcctg tttttatttc aggcaatcgg ggtgaatgtg gcgcaggcgg aagtgttgaa
     2521 tctggagtcc ggagctaaac aggttttaca agaaaccttt ggctaccaac agtttcgccc
     2581 cggccaggaa gagattatcg acaccgtact ttccggtcgc gattgcctgg tcgtcatgcc
     2641 cactggtggc ggaaaatccc tttgctatca aatccctgcc ttattgctaa acggccttac
     2701 cgtggttgtc tcaccgctga tttcgttgat gaaagatcag gtagatcaac tgcaagccaa
     2761 cggcgtggcg gcggcgtgcc ttaactcgac gcaaacccgc gagcagcaac ttgaagtgat
     2821 gacaggctgt cgcaccgggc aaatcagcct gctttatatc gcgccggaac gcctgatgct
     2881 ggataacttt cttgagcatc tggcgcactg gaatccggtg ttattagccg ttgatgaggc
     2941 gcactgtatc tcccaatggg gtcacgattt ccgcccggaa tacgctgccc tcggtcagct
     3001 gcgtcagcgt tttccgacgc tgccgtttat ggcgctgact gccacagccg atgacaccac
     3061 gcgccaggat atcgtgcgcc tgctggggct gaacgatccg ctgattcaaa tcagcagttt
     3121 tgaccgtccg aatattcgct acatgctgat ggagaaattc aaaccgctcg atcagttgat
     3181 gcgttatgta caggaacaac gcggtaagtc ggggattatt tactgtaata gtcgtgcgaa
     3241 agtagaagac accgctgcgc gcctgcaaag caagggaatt agcgcggcgg cctatcatgc
     3301 cgggctggaa aataatgttc gcgctgatgt gcaggaaaaa ttccagcgcg atgacctgca
     3361 aattgtggtg gcgacggtgg cgttcggcat gggcatcaac aagcctaacg ttcgcttcgt
     3421 ggtgcatttt gatattccgc gcaatatcga atcctattat caggaaactg gacgcgccgg
     3481 gcgtgatggc ctgcccgcgg aagcgatgct gttttacgat ccggctgata tggcgtggct
     3541 gcgccgttgt ctggaagaga agccgcaggg gcagttgcag gatatcgaac gtcataaact
     3601 caatgcgatg ggcgcgtttg ctgaagcgca aacttgccgt cgtttggtat tgctgaacta
     3661 ttttggcgaa gggcgtcagg agccgtgcgg gaactgcgat atctgcctcg atccgccaaa
     3721 acagtacgat ggttcaaccg atgcgcagat tgccctttcc accattggtc gtgtgaatca
     3781 gcggtttggg atgggttatg tggtggaagt gattcgcggt gctaataatc agcgtatccg
     3841 cgactatggt catgacaaac tgaaagtcta tggcatgggc cgtgataaaa gccatgaaca
     3901 ttgggtgagc gtgatccgcc agctgattca cctcggcctg gtgacgcaaa atattgccca
     3961 gcattctgcc ctacaactga cagaggctgc gcgtccggtg ctgcgcggcg aatcctcttt
     4021 gcaacttgcc gtgccgcgta tcgtggcgct caaaccgaaa gcgatgcaga aatcgttcgg
     4081 cggcaactat gatcgcaaac tgttcgccaa attacgcaaa ctgcgtaaat cgattgccga
     4141 tgaaagcaat gtcccgccgt acgtggtgtt taacgacgct accttgattg agatggctga
     4201 acagatgccg atcaccgcca gcgaaatgct cagcgttaac ggcgttggta tgcgcaagct
     4261 ggaacgcttt ggcaaaccgt ttatggcgct gattcgtgcg catgtcgatg gtgacgacga
     4321 agagtagtca gcagcataaa aaagtgccag gatgaagact ccgtaaacgt ttccccccgc
     4381 gagtctaatg tatgttgatg ttattcctca ccgtcgccat ggtgcacatt gtggcgctta
     4441 tgagccccgg tcccgatttc ttttttgtat ctcagaccgc tgttagtcgt tcccgtaaag
     4501 aagcgatgat gggcgtgctg ggcattacct gcggcgtaat ggtttgggct gggattgcgt
     4561 tgcttggcct acatttgatt atcgaaaaaa tggcctggct gcatacgctg attatggtgg
     4621 gcggtggcct gtatctctgc tggatgggtt accagatgct acgtggtgca ctgaaaaaag
     4681 aggttgtttc tgcccctgcg ccacaagtcg aactggcgaa aagcgggcgc agttttctta
     4741 agggcttact gaccaatctc gcgaatccta aagcgattat ctactttggt tcggtgttct
     4801 cgctgtttgt cggtgataat gtcggcacca ccgaacgctg gggcattttc gcgttgatta
     4861 ttgtcgaaac actggcgtgg tttaccgtcg ttgccagcct gtttgctctg ccgcaaatgc
     4921 gctgtggtta tcaacgtctg gcgaagtgga ttgatggttt tgccggggcg ttatttgccg
     4981 gatttggcat tcatttgatt atttcgcgtt aagcgcttcc cccctgatac gctatcaggg
     5041 ggaataacat caggattgca attgataaag gtcttcctga gaaagcccgg tcatttccat
     5101 aatcaactgc aaatcaaagc cacgctgtag catggctttt gcgacattga gaagggcatc
     5161 gcgccgaagt tcttccgcta aagtcatcag ttcctctcct tgttgaggca ctcgttgtgc
     5221 cagaccatgt actaatgttc gtacatcctg tgcttcacct accagcgcca tgtagtttat
     5281 caacatgcgt atttgctgtc cgctcatctg ccccagaatc attaagcggg ataacttatc
     5341 taacagcgtt gtcatatccc gttgacggat atgcttctgt accagcgtaa aggcggccat
     5401 gctgcggtgt tgcatgattt cgtcatcagg aattagcgta atatcaacca gcggaaaagc
     5461 atgaaaatag agatcgcgtg caatgtccgg atccggaaaa ccatcgagcc agtttgttga
     5521 ccatggatat gggctacgct ttccctggta aaaaagaatg gggatcacca gaggcagata
     5581 atcatgtccc gcttcaagat gccgctgcat ggtggcaata gcatagcgaa gcatacggaa
     5641 cgccatattt tcatcaggtg aactttgatg ctcaatcaac acatagatat atccgcaccc
     5701 tttcgtcgtc tctactgaat aaagtacgtc gttgtaatac tggcgtaggt tttcctctac
     5761 aaaactgctg gactcgagat ggagcgtatc aagattgcag agtttaacta aagaaggcgg
     5821 cagatgaatt tcaataaagt cacgggccgt ttctggtcgg gataaaaaag ccttaaagat
     5881 tgcgtcatgt ggtgtcgttg cttccgtcat ttttcatcat ccgtgggtga aatatggcgg
     5941 cattctggca ctaacaaaga gaagtaaata gtaaataaat taacagatta cgcttattac
     6001 gagatgcctc gagcgcggat gtaacaatct ctcgaggcac attaatttac gtgagcttta
     6061 ttccagtttt aagcatgcct cgccgatgct aacagcgctc ccaccagcat aaataacgag
     6121 ccgaaaatct tattcagcgc cttcatctgc tttggtcctt taatccatag agcaatccgt
     6181 tgagcaaggg tggcgtaacc gatcatcaca ataatatcga ccacaatagt ggtgacgccg
     6241 agcacgatat actgcatcag ctgcggctgt tgcggcatga tgaattgcgg aaatagcgcc
     6301 gccagaaaca caatactttt gggattggtg agattgacaa aaactgcgcg ctggaacaaa
     6361 tgtcgacgcg attgagtaga ggccagcgat ttaagatcaa ttgcgccagc ggcgcgccac
     6421 tgctggatcc caagccaaat caagtaagct gcgcctgccc acttcaacac ttcaaacgca
     6481 atcactgagc gggaaaatag cgtccccaac cccacgccaa ccagcacaat atgaatcgcc
     6541 agtccggtct gaagcccagc aatagacgcc accgcgccgc gataaccgtg gttgagcgag
     6601 gtggtcatgg tgttgattgc gccagagcct ggcgacaggc ttaaaatgat cgatgtcagc
     6661 aggtaggcaa accaccattc taaggtcatg atgaactccc ggtgtgtcta tttttgtgcc
     6721 acaatacgct actgtcgcag cgttgtgtca ggcacgctta aaaaaacgat tttacgtggt
     6781 ttaagaggca gattacccga tgtttcagca gcaaaaagac tgggaaacaa gagaaaacgc
     6841 gtttgctgct tttaccatgg gaccgctgac tgatttctgg cgtcagcgtg atgaagcaga
     6901 gtttactggt gtggatgaca ttccggttcg ctttgtccgt tttcgcgcac agcaccatga
     6961 ccgggtggta gttatctgcc cggggcgtat tgagagctac gtaaaatatg cggaactggc
     7021 ctacgacctg ttccattcgg ggtttgatgt tttaatcatc gaccatcgcg ggcagggacg
     7081 ttccggtcgc ctgttagccg atccacatct cgggcatgtt aatcgcttta atgattatgt
     7141 tgatgatctg gcggcattct ggcaacagga ggttcagccc ggtccgtggc gtaaacgcta
     7201 tatactggca cattcgatgg gcggtgcgat ctccacatta tttctgcaac gccatccagg
     7261 tgtatgtgac gccattgcgc taactgcgcc aatgtttggg atcgtgattc gtatgccgtc
     7321 atttatggca cggcagatcc tcaattgggc cgaagcgcat ccacgtttcc gtgatggcta
     7381 tgcaataggc accgggcgct ggcgcgcgtt gccgtttgct atcaacgtac tgacccacag
     7441 cagacagcga tatcgacgta acttacgttt ctatgctgat gacccaacga ttcgcgtcgg
     7501 tgggccgacc taccattggg tacgcgaaag tattctggct ggcgaacagg tgttagccgg
     7561 tgcgggtgat gacgccacgc caacgcttct cttacaagct gaagaggaac gcgtggtgga
     7621 taaccgcatg cacgaccgtt tttgtgaact acgcaccgct gcgggccatc ctgtcgaagg
     7681 aggacggccg ttggtaatta aaggtgcgta ccatgagatc ctttttgaaa aggacgcaat
     7741 gcgctcagtc gcgctccacg ctatcgttga ttttttcaac aggcataact cacccagcgg
     7801 aaaccgctct acagaggttt aaatttctta tgtaccaggt tgttgcgtct gatttagatg
     7861 gcacgttact ttctcccgac catacgttat ccccttacgc caaagaaact ctgaagctgc
     7921 tcaccgcgcg cggcatcaac tttgtgtttg cgaccggtcg tcaccacgtt gatgtggggc
     7981 aaattcgcga taatctggag attaagtctt acatgattac ctccaatggc gcgcgcgttc
     8041 acgatctgga tggcaacctg atttttgctc ataacctgga tcgcgacatt gccagcgatc
     8101 tgtttggcgt agtcaacgac aatccggaca tcattactaa cgtttatcgc gacgacgaat
     8161 ggtttatgaa tcgccatcgc ccggaagaga tgcgcttttt caaagaagcg gtgttcaatt
     8221 atgcgctgta tgagccggga ttgctggagc cggaaggcgt cagcaaagtg ttcttcacct
     8281 gcgattccca tgaaaaactt ctgccactgg agcaagcgat taacgctcgc tggggcgatc
     8341 gcgtcaatgt cagtttctct accttaacct gcctggaagt catggctggc ggcgtttcaa
     8401 aaggccatgc cctggaagcg gtagcgaaga aactgggtta cagcctgcaa gattgtattg
     8461 cctttggcga tggaatgaac gatgccgaaa tgctgtcgat ggcggggaaa ggctgcatta
     8521 tgggcagcgc gcatcaacgg ctgaaagatc tgcatccaga gctggaagtg attggtacta
     8581 acgccgaaga cgcagtgccg cattatctgc gtaagctcta tttatcgtaa tcgttcttta
     8641 tttggtcagt tgtcaacctg atacttcgct acaatggata ctcgttaatc aaagagtttt
     8701 ccattgtggc gctacttatc atcaccacga ttctgtgggc cttctccttt agcttttatg
     8761 gcgagtacct tgcggggcac gtcgatagct attttgcggt gctggtgcgc gttggtctgg
     8821 cggcacttgt ttttctgccg tttctgcgta cccgtggcaa tagcctgaaa acggtcggcc
     8881 tgtatatgct ggtgggcgcg atgcagctcg gtgtgatgta tatgctgagt ttccgcgcct
     8941 atctctacct gacggtttct gaactgctgt tgttcaccgt actgacgccg ctctacatca
     9001 cgctgattta tgacatcatg agtaagcgcc gtctgcgctg gggctatgct tttagcgcct
     9061 tgttggcggt gattggtgcc gggattattc gctatgatca ggtcaccgac catttctgga
     9121 ctggcttgtt gctggtgcaa ctctccaata tcacttttgc catcggcatg gtgggttaca
     9181 aacgtctgat ggaaactcgc ccgatgccgc agcataacgc ctttgcgtgg ttctatcttg
     9241 gcgcgttcct ggtggcagtg attgcatggt tcttgctggg aaatgcgcag aaaatgccgc
     9301 aaaccacgtt gcaatggggc attctggtgt ttcttggcgt ggtggcttcc gggattggct
     9361 actttatgtg gaactacggc gcgacgcagg tggacgccgg aacgctgggc attatgaata
     9421 atatgcacgt tccggcaggg ctgctggtaa acctggctat ctggcaccaa cagccgcact
     9481 ggccaacgtt tattacaggc gcgctggtga tcctggcctc actgtgggtg catcgtaagt
     9541 gggtcgctcc gcgctcttca caaacggcag atgatcgcag gcgtgattgc gcgctgaacg
     9601 aataaacgct tctgtaatcg gctgacgctg ctcgccatcg cgcacggcgg cgtacagtcg
     9661 gctccacaag ccttcgccca gggttttggt gaccaccaga ccctggcgtt caaaactctc
     9721 caccacccaa tgaggtagtg cggcaatacc catccgtgcg gcaaccatct gaatcaacaa
     9781 taaggtgtta tcgacgcttt tcagtgacgg gctgacgcct gctggctgaa gaaaatgccg
     9841 ccagacatcc agtcggctac gctgcaccgg ataaatcaac agcgtttcgc tggcgagatc
     9901 ttccggtgta atacgcgttt ttgccgccag tggatggtca ggtgctaaca ccagacgtac
     9961 ttcatagtcg aacatcggcg aataatgcag gccactgcgc ggcagaatat cggacgtcat
    10021 caccagatcc agctcgccct gttgcaacgc aggctgcgga tcaaacgtta cgcccgattt
    10081 aaaatccatc tccacctgcg gccagttctt atggaaattt tctaatgcgg gcgtcagcca
    10141 ctgaatacag ctatggcact ctatggcaat gcgcaggcgc gtctgctgcg gttcattgca
    10201 ggcttgcagt gcctggctaa tttgcggcag cacctgattt gccagttgca acaggatttc
    10261 tccctgcggt gtaaagcgaa gcggctggct tttacgcaca aatagccgga agccaaggcg
    10321 ttgttccaga tcgctaaact ggtgagacag ggcggattgc gtttgatgca acgtcgccgc
    10381 agcggctgcg agtgagccgc agttccgcaa cgcttgtagc gttttcaggt gttttacttc
    10441 gatcatgaaa gtccttcact tcggcatgaa taatttgcgc ttgaggaata tacagtaacc
    10501 gccaattatg gatgtgtaaa catctggacg gctaaatact aaaaattcca taaggggcat
    10561 ataatgacaa ttcttaatca caccctcggt ttccctcgcg ttggcctgcg tcgcgagctg
    10621 aaaaaagcgc aagagagtta ttgggcgggg aactccacgc gtgaagaact gctggcggta
    10681 gggcgtgaat tgcgtgctcg tcactgggat caacaaaagc aagcgggtat cgacctgctg
    10741 ccggtgggcg attttgcctg gtacgatcat gtactgacaa ccagtctgct gctgggtaat
    10801 gttccgcaac gtcatcagaa caacgatggt tcggtagata tcgataccct gttccgtatt
    10861 ggtcgtggac gtgcaccgac tggcgaacct gcggcggcag cggaaatgac caaatggttt
    10921 aacaccaact atcactacat ggtgccggag ttcgttaaag gccaacagtt caaactgacc
    10981 tggacgcagc tgctggagga agtggacgag gcgctggcgc tgggccacaa ggtgaaacct
    11041 gtgctgctgg ggccggttac ctacctgtgg ctgggtaaag tgaaaggtga acagtttgat
    11101 cgcctgagcc tgctgaacga cattctgccg gtttatcagc aagtgctggc agaactagcg
    11161 aaacgcggca ttgagtgggt acagatcgac gaacccgcgc tagtgctgga actgccgcag
    11221 gcgtggctgg atgcatacaa acccgcttac gacgcgctcc agggccaggt gaaactgctg
    11281 ctgaccacct attttgaagg cgtaacgcca aacctcgaca cgattactgc gctgcctgtt
    11341 cagggtctgc atgtcgatct tgtacatggt aaagatgacg ttgctgaact gcacaagcgc
    11401 ctgccttctg actggctgct gtctgcgggt cttatcaatg gtcgtaacgt ctggcgcgcc
    11461 gatcttaccg agaaatatgc gcaaattaag gacattgtcg gcaaacgtga tttgtgggtg
    11521 gcatcttcct gctcactgct gcacagcccc atcgacctga gcgtggaaac gcgtcttgat
    11581 gcagaagtga aaagctggtt tgccttcgcc ctgcaaaaat gtcatgaact ggcattgctg
    11641 cgcgatgcgc tgaacagtgg tgatacggca gctctggcag agtggagcgc tccgattcag
    11701 gcgcgtcgtc actctactcg tgtacataat ccggcagtag aaaagcgtct ggcggcgatc
    11761 accgcccagg acagtcagcg tgcgaatgtc tatgaagtgc gtgctgaagc ccagcgtgcg
    11821 cgttttaaac tgcccgcgtg gccgaccacc acgattggtt ccttcccgca aaccacggag
    11881 attcgtaccc tgcgtctgga ttttaaaaag ggtaatatcg acgccaataa ctaccgcacg
    11941 ggcattgcgg aacatatcaa gcaggccatt gttgagcagg aacgtttggg actggatgtg
    12001 ctggtacatg gcgaggccga gcgtaatgac atggtggaat actttggcga gcatctggat
    12061 ggctttgtct ttacgcaaaa cggttgggta cagagctacg gttcccgctg cgtgaagcca
    12121 ccgattgtta ttggtgacgt tagccgcccg gcaccgatta ccgtggagtg ggcaaaatat
    12181 gcgcaatccc tgactgataa accggtgaaa gggatgttga ctggcccggt gactattctc
    12241 tgctggtcgt tcccgcgtga agatgtcagc cgtgaaacca tcgccaaaca gattgcgctg
    12301 gcactgcgtg atgaagtggc cgatctggaa gccgctggaa ttggcatcat tcagattgac
    12361 gaaccggcat tgcgcgaagg tttaccactg cgtcgcagcg actgggatgc ctatctccag
    12421 tggggcgtgg aggctttccg tatcaacgcc gccgtggcga aagatgacac acaaatccac
    12481 actcacatgt gttactgcga gttcaacgac attatggatt cgattgcggc gttggacgca
    12541 gacgtcatca ccatcgaaac ctcgcgttcc gacatggagt tgctggagtc gtttgaagag
    12601 tttgattatc caaatgaaat cggtcctggc gtctatgaca ttcactcgcc aaacgtaccg
    12661 agcgtggaat ggattgaagc cttgctgaag aaagcggcaa aacgcattcc ggcagagcgt
    12721 ctgtgggtca acccggactg tggcctgaaa acgcgcggct ggccagaaac ccgcgcggca
    12781 ctggcgaaca tggtgcaggc ggcgcagaat ttgcgtcggg ggtaaaatcc aaaccgggtg
    12841 gtaataccac ccggtctttt ctcattacag cgacgtcttc ccagcatact gcgtaaacca
    12901 ttccagatat cagttcatac cctgtttaag aaaatcttct ttattccctt ctcatgaaat
    12961 aaatttcgtc atttccgcca ttttttctat ctgcctctcc atcacatatt aaaaattact
    13021 tgatatctct atgtttttta atgaaaaaca tatcaaccta tgatctttct tgtgactagc
    13081 ttcacatttc atactgatgc attggaatga aataaaattt catgagattt tgtgtttgag
    13141 aaaattattt catgaggtgt gaaatggacg caaagctgta catcactgag atcatcaatg
    13201 aattaacctt cgttaaggac tctatccgtg aggatgactg caccaaattg atcgacacta
    13261 ttcagcaaag ccagcgcgtt ttctgctatg gcctgggacg cgccggtttt tctatgaaag
    13321 ccttcaccat gcgcctgatg catatgggaa aagaggttta cttcctgacg gaaaccatta
    13381 cgccgaactt tgggcctggc gatctgttta tcgtttcttc tgcttccggt gagacagcac
    13441 aactggtggc gctggcgaaa aaagcacgtc agctcggcgg cgctgtggcg gtgttaacca
    13501 cgaatcgaca cgccactatc accgagtttg tcgacgtcat cgtgcaaatc aatgcccctt
    13561 ccaaaaatca aaaagattct gttttccgct cggcacagcc gatggcgtcg ttgtatgagc
    13621 aagctttgct ggtgattgcc gatgcattag tgatgaagat ggctgctgaa agtggtgcgc
    13681 cggaaagtga actgtttaag cgccacgcca atctggaata gtcgtcgccg ttatttgctc
    13741 gataccctac aggagaataa aaatgagcaa aaaaataaca tccttgttta acttcaagaa
    13801 gttgcagaaa ttttcttctg ctctgatgtt accaatcgcc attcttccgg cggcgggttt
    13861 gattttagcc atcgggattt catttaacat tgagctgctg gcgaattgcg gcggcctgat
    13921 tttcgccaac cttcctttgc tgttttgtgt cggtattgtg attggcctga caggtgatgg
    13981 ttcttcatca ctttcagcga ttatcagtta catgatcatg aatgccacga tgggaacgca
    14041 acttggcatt actgcggagt ccgttgcagc cagtaacggt gattatgcga tgatcctcgg
    14101 ggtaccgacg ttacaaacgg gagtgtttgg cggtctgatt gtcgccatct ttgtttatct
    14161 gctctatacc cgcttccaca atattgaatt gcctcagttt cttggtttct tcggtggaaa
    14221 acgctttgta ccgattatta cggctgtggc ggcaattatt gtcggctatt tattgccgtg
    14281 gctgtggata ccggtacaaa aaggtctggc gtcgctttca acgctggtga ccagtggaca
    14341 taacgcgaac ttcgcggcct ttatttacgc cgttggcgaa cgttcgctga ttccttttgg
    14401 cctgcatcat atctggaacg tgccgtttta ttacaacttt ggcgactaca tgaccaaatc
    14461 cgggcaactg gtgacgggcg atattccggt gttctttgcc caattgcgcg acggtgctcc
    14521 gttgacggcg gggctgttta tgacaggtcg tttcccgatc atgatgtttg cgttacctgc
    14581 cgccgcgttg gcgatgtatc aggaagcaaa accggaacgt aaggcgctga ttaaaggcct
    14641 tttactctcc ggtgcgctga ccacatttgt taccgggatt acggagccgc tggaatatgc
    14701 atttttgttt gcagcgccgg ttctctacat cattcacatc ttcttatatg ccacttcatt
    14761 tgtgctgatg aacatcctga atgtgcacat tggtcatcct tttgctggcg gtcttattga
    14821 tttcgtactg aatggcgtta tgccaaaccg cacgccgtgg tatctggtgt tcctggcagg
    14881 cgcgggctat gcagcgattt actacaccgt atttcgggta ctgatccgca agttgaatct
    14941 gaaaacaccg gggcgtgagg atgaagagat tgccgttgca accacattag cgcgcgaaga
    15001 acgtccatac caaatcatcg aagcagtagg tggtttcgac aatatcgaag atgtggatgc
    15061 ctgcgcaaca cgcctaaggc tggcgctggt agacgataag aaagtgaatg aaaaacggct
    15121 gaaggagttg ggggctgcgg gtttagtgaa actgggtgat ggcggtgtac aggtgatatt
    15181 tggcggcaaa tcgcaaatcc tgcgcgacga aatcaaaacc gtaatgagca gaccgcgccc
    15241 gacagaaatg acagtggcct gtgctaacta attcgagatt agcgggctgg tttcagcccg
    15301 ccagacagag agagctgaag tatgaattca caattactgg ctaatgccat ccgaatgtta
    15361 agtgttgatg cgatccagaa agcgaactcc ggtcatccgg gcgcgccgat ggggatggcg
    15421 gatattgccg aagtggtctg gcgtcgtcac ctgcgtcata acccaaaaaa tccgcagtgg
    15481 tttaaccgcg accgctatgt tcagtcgaac ggtcacggct ccatgttgat ttacgctttg
    15541 ctgcatctta caggctacga cctgtcgatg gatgatattc gcgactttcg tcagctccac
    15601 tcccgcacgc cgggtcatcc agaatatggt tatacgccgg gtgttgaaac caccaccggc
    15661 ccgttggggc agggcgtagc taatgcggtg gggatggcga ttgcggagaa ggcgctggcg
    15721 gcagaattta acaaaccggg ctttaatatt gttgatcatc acacatggtt atttttgggt
    15781 gatggctgtc tgatggaagg gatctcccac gaggcctgtg gtcttgcagg aacgctgaag
    15841 ctcggcaatc tgattgctat ctgggacgat aacggtattt cgatcgatgg tcacgtagaa
    15901 ggctggttcg ctgaagatac ggctgcccgt tttcgtgcct acggctggca tgtcattgaa
    15961 ggcgttgatg gtcacgatcc agaagcggta gatgctgcgg tgcgtgaagc gaaaagcgtc
    16021 acggataagc ccagtctgct gtgctgcaaa acgattatcg gttttggttc gccaaataaa
    16081 gccaacagcc acgattgcca cggctcggcg ctgggtgcag atgaagtggc gctggtgcgt
    16141 gaacgtctgc aatggccgta tgcccctttc gaaattcctg gtgaaattta tgccgaatgg
    16201 gatgcgaccg agaaaggcgc gcaggttcaa caggaatggg atgcactgtt tgccgactac
    16261 gcgaagcagt ggccggaact ggcggcggag tttactcgtc gcatgaaggg tgatttgcct
    16321 gctggctggg tcgagaatat gcagaaatat gtgcacgatc tgcaatccca tccggcggcg
    16381 ctggcaaccc gtcaggttag ccagaaatgc ctcaatcact tcgcagatat gctgccggaa
    16441 ctgatgggcg gctcggcgga cttgtcgccc tctaacctga ctcgccatca gaaatcggtt
    16501 gatttcaccg gagaaaatcc ggcggggaat tacatctcct atggcgtgcg tgaatttggt
    16561 atgtcggcca tcatgaacgg tcttgcgctg catggtgggt ttatccctta cggcggtact
    16621 ttcctgatgt ttatggaata tgcgcgtaat gcactgcgca tggcggcgct gatgaagatc
    16681 cgctcggtgt ttgtttatac ccacgatacc atcggcctgg gcgaagacgg cccgacacat
    16741 cagcccgttg agcaactggc gtcgctgcgt ctgacgccga atatggaaac ctggcgcggt
    16801 tgcgatcagg tggaagtggc ggtggcctgg caacaggcga ttgagcgcaa agatggccca
    16861 acgtcgttgg tattaacgcg ccaacctctg gcgcaacagc cgcgcaccgc tgcacagttg
    16921 gcagagattg cgcgtggtgg ttatgtactg agtgattgtg acggtcagcc tgagatgatc
    16981 ctcatttctg cgggttcaga gattgagtta gtggtcagcg ccgcaaaagc gttaacggaa
    17041 gaagggcgta aagttcgcgt ggtttccatg ccgtgtaccg agcgtttcga taatcaggat
    17101 gcggcgtaca aagagtcggt attgccaaaa gctgtacgca aacgtctggc ggtagaagcc
    17161 agcatcgccg gattctggga acgctacgtg ggcctggacg gtaaagtgat cggcatgacg
    17221 agctttggtg agtctgctcc ggcgaatgtg ttgttcaaac actttggttt tacgccggaa
    17281 aatgtcctgg cgcaggcgcg tgagctactg aacagctaaa cctgcacaag gggtgaaagg
    17341 atgacctttt accccttgaa acgggagcca agaaactctt cacgggtgcg gtatttctcg
    17401 taatgcgcct tgtttttata cataaacaac agcaccagca tatcaataac gcccattgcc
    17461 ggaacgcgag tggagtcgaa ggcttcaaag aagattttat cgctgaccgc ggtattgagt
    17521 tgatgggtgg agagttttga taacggagat ttaatatagt tagtgataca aacggatttg
    17581 gcaccgcgct ctttcaccac tttaaagata tcgaccatta agttggtgct gccagagtta
    17641 gaaataccaa tcgccaggtc gcgtttcccc atagaatatg ccgcattaat ttgcatttcc
    17701 gggctgacgt gaacaacggt ttttaatccg agttggctga atttataagc actataaacg
    17761 gccagtgggt ttgaatttcc ggcagcaaaa aagaaaatag tatcgcaatt agcaagtagt
    17821 ttgagaatgg actcaagcac gtcggcatta aaaaattgcg ttgattgtat taaatcttcg
    17881 gcctgttttt ttaataaaaa ggttgccaaa gatgttatat cgctgaagtc ggtattttca
    17941 ggatagctat tgtcaggatt aatgacttct tttgctaatg caatttttaa atggtaataa
    18001 ccctgataac ctaatttctt acaggtgcgt acgatagtcg cttcactggc atggcttttt
    18061 tctgatagtt cagtgacact atagttcacg acttcatgtg cgtggctaag aatatagtca
    18121 gcgacctttt tttccgcctg atgcagtgta gggtaattgc tttgaatcag actttttacg
    18181 gttatgttat tcataattag taaatttcat tctgacagaa agtgctgatt ataacatagt
    18241 tttcaggcgt ggataggtgt gaaaaaatga aggtgtgcag tgaacgtaat gattaacaga
    18301 ccggttaatt ttcatgaatt acgtcaactg cacaaaaata atttaaacgg gcgctctaat
    18361 taaagcaaga cttatatttt tatcattgta ttgtcaatta aatacaaatc gtgtcattaa
    18421 ttgctggttt cttaaatatt ctatgcacca ctgacaggct ttgcccatac catcggaacg
    18481 agcggcaaga aataacttgg tggcgtgttt atgttcgcgc attggctttt taagcaattt
    18541 accgctgttc aataacggta atgccagatg atgtggaata taaccaatac cgacgttttg
    18601 ttctattaag gcgattgccg tagcgaagtc aggaacaaaa atgggttttt gtccttccaa
    18661 caaccaggct tgcatcgggg ggaagttaac ggaggtatcg cggatacaaa ccgctggata
    18721 atgacgcaat tcactgtttt ctaatggatg ccgcttcgct gccagtgggt ggagtgggct
    18781 gacgacaaaa tcccattcca tttgtccgac cggttcgcta atgatgcctt cactgcttgg
    18841 tactgcatga ggagcaccgt agaccagatc agcacgctta ctgtacagcg catcccagca
    18901 gccgttgtat acctcaagat ctaccgtcag tgttgttgat gtgaattgcc gttcaaaatc
    18961 tcgaataaat gccaccagca aatcaccagg aataatattg tttaccgcaa ttgtcagttc
    19021 acgctcaata ccatcgtgaa tcagcactgt gttgcgcttt aatgcttcca ggtcgccaag
    19081 aatagttttg ctatgttcga tgaagtaact tcccgctggc gataattcaa tatagcgtcc
    19141 cttacgaatg aacagttcaa cgcccaggct ctcttccgct ttcttgatgg tgtaactgat
    19201 ggcggaaggg actttattta actgctcggc tgcggtggta atgctctggt gtctggcgac
    19261 cagatgaata acacgaagcg tttcgtctga gatgaacata aggctccctg gtcagtggta
    19321 aagtggctga atctctccag attcagccgt aatcattgcc tgagtatacc caggaattag
    19381 cggtgttgac ttgcccgact gagaatcgca tacgcgatac atgccaccag aatcgagtct
    19441 accgaaggga tcgtcgtcag ggtgaataag ccttttacgg tcataaagcc aaccgctgcg
    19501 cctatgatcc atgctgcgaa tgtcagcact ttaatctgtg actcctgggc taacactgac
    19561 tcttgatagc cattacggcg ataaaggaaa aagtcagcga tataaattcc ggcaacgggt
    19621 ggcgtggcga tacccaggaa cagcagaaac ggaataaacc acgccataat atccatactg
    19681 cctacgatgg cggaaaggat acccagcgcc acggtaatct gccatttggg aaagcgggta
    19741 agcagtgtgg aaaccaccag cgtgccctgg aacatattgc ccgcgttacc ggtgacgcag
    19801 gcgaaaatca acaacagcgc cgcaggcaga actgcaccga ataccgccat cgcacccagt
    19861 aaagatccct gaccactaat ggcgctcggc gttgcacccg cccagtagag cagagggtag
    19921 gcaaccagaa acgtcacgcc tgcggcaatc agcgcatgtt tgcggttatg cacaaaacta
    19981 ccgaaatcag gcagtgtggc aaccagcaca ataatggtgc caacaacggt ggaaacggcg
    20041 acacctgtat tcatctccac aatcgccgct ggtactgcca cttcggtatg ggttgccaca
    20101 tagaggatgt aacacagcac cagcgcgata accggcacgg caacctgggc aatttttccc
    20161 agaacggcaa agccaaatgc cgtagaggcg acaaaaatga cacagccagc cgccactaac
    20221 agtgccagtg gaacttccag tccatgttga gccagtaagt catgtaccga atgaccaaac
    20281 atattggcgg taacggcaat ccagccgaac agacttatcg ccatcaaaat gttaatggcg
    20341 atggcccctt tttcgccaaa cgaatatttc acaatgccat acgttggcag gcgggctttt
    20401 tctcccacgc taatggtgat ggctgaaagt aaggtcagaa tgacgccgcc taacaatacg
    20461 acgctaatta aactgccgct ggaaagttga ttgccgaggc ttgaggatga caacagcaca
    20521 ggtgtgacgg caatacccag caaaatcatg gcaatacgca atcctgatgc cgtattcaga
    20581 ttctcttctt ttttacgcat agtatgttcc ctttataaat gcgcgttaca cagtatgaaa
    20641 atgcccggtg tatttacgcc agctacccag ttctgtaatt tcccgttggc cttcggtcag
    20701 ccagttttct gccagtacgc ccagcacttc gctaccatcg gcaagtttga ttttgccaat
    20761 tgccagccca gcgggttcgc tcattaacag agcggcaaaa ctggccagcg gtaattgcca
    20821 aatttctacg tcgacgtgtg ttcctccttc attcacgcga atcattcccg gatggcgatc
    20881 attaatactc cacaaccggt aatgggcgtc agttcggtct tcacggacaa aaataccgcc
    20941 cgctttttgc atatttgggt tgagttccag gccgcgcatc agcgttccgt taacggctaa
    21001 aagcgttgta gtcattgtgt tctccagaga attaaagggt tatccatgta ccgctctgat
    21061 gcgccagggc tgcttttatg gtttgcggtg aagtaatcag gccgctggcc tgtttgcctt
    21121 gttgctggct ggcattgatg aaatcaacaa tggcttccac tttgggttgc atactgccga
    21181 caccaaactg accttcccgc aacagcgttt gcgcttcggc aacgctgata gcgtcgagcc
    21241 actgttgttg tggtgtacca aagttaatcg ccactttttc tacaccggtg gggatcacca
    21301 gcagatctgc gcctaactga ctggcgagca gcgcggaggc cagatcttta tcgatcacgg
    21361 cttctacacc tttcagttgt tgcccgtctc gcaccaccgg aataccgccg ccgccgcagg
    21421 caataaccag atatccctgg cgcaccaggt gagcgatggt gtcgtgctca ataatttcca
    21481 gtggtgcagg agagggaact gtacgccgcc aaccacgccc ggcgtcctcc atcagcgtcc
    21541 agccgagttg ttgttggcgt tgttgggccg ttgcttcatc gagaaacgcg ccaatcggtt
    21601 tactggggct ggcgaaagca tcgtcatgtg ggctgactcg cgtttgtgtc accagggcaa
    21661 ttaccggttt gtttatgcca cggcgagcga gttcgttatg cagcgctttc tggaacatgt
    21721 agccaattgc accttgtgta tcacccacgg cgtaatcaag tggaaccgga gaaacttcgt
    21781 tactggcgag ttcagagcgg cgcagaataa agcccacctg cgggccatta ccgtgggtta
    21841 gcaccaggtc ccatccggct tcaaccatat caacgatatg ctgcacgctt tccatcactg
    21901 caacatattg atcgggaata ctattgcgtt gctcgtcctg aatgagcgca ttgccgccaa
    21961 ccgcgacgac agccagtggc ttaaccatga tggttctcct ttgcgacgat ctccgccagt
    22021 gcacgtacag cggcgacaaa acaggccatc ggcgcagtgg tgatcccggc accaatttgc
    22081 ccgacccccg cttgtttgtg ggcgataccc gtattgatga ccggtaaaat gccgcgatcg
    22141 gtcactttac gcgcatcaat ccctgctgcg gtgggggcaa aattgagggc tggaagtgta
    22201 aatgcggggt taccgccgag ggtgatggct tgcatccgac ggctgttatt ggtggcatcg
    22261 gcaggggtgc ctcccacaaa tttgacgatc gccggagacg acgccatcgc gaagccaccc
    22321 acacctgcgg tttcagtaat tgcgctatca cccaggtcag cagcagcgtc gtcaacgcca
    22381 aatccgggga agaacagacc ttcaacggca ttggcaggag cctggaacca gcgatcgcca
    22441 gtaccggaaa tccgaatacc aaaattcacc ccgttacgcg ccatcaccgt aaccattgaa
    22501 ctgaacggta cattggcggc ggcatccatc attgctttac aggcggccat cgacagattg
    22561 aggaagaagt gatcgttacc ggtgataaat gccacgacgc gctggatatg ttcctgtgga
    22621 agagagcagg ccagcaatgc cgggagcagg cgcttaatca gcaaaccggt agcggcagca
    22681 ttgcggttat gaacttcatc ccccatatgc agcgcctgcg ccattaatgg cttgagttcc
    22741 agctcgccgt gttgtgcgat tgctgctttc attgccggcg tcagttcatc gcgcatccag
    22801 gccagacgat tgagaacttc atcgttattg gcgccaaaac ggagaacctt acccagacct
    22861 tcattgaaat tgctaaaagt acggtggccg ttggttttgt tttctaccac ccataacggc
    22921 atcgacgggc tgatgatgcc tgccattggg ccaaccgcgt gataatgatg acaaggggca
    22981 aggtcgattt cgcctgcgtt tatctggttt tcagcgtctt gctggctggt ggcccaacct
    23041 tcgtacagca tggcaccaat aatcgcccct tttaccggac cacacatctc ttcccaggca
    23101 atcggcgggc cagagtgcaa aatacgtttt tgttcagcca ttgctggaat ggcctcttta
    23161 gcaagcatga catccaccag cacgggctgt gcttcgagat aacgtgccat ggcgatttgg
    23221 ttggcatttt ctaccagggg atgacgtagc aacgatgcca gatccaatcc agcgtcaata
    23281 tcgccttgtg ctggtggctg ccagttgagt gcaattgcgc ttcccccggc atgttgaata
    23341 ttgtcagcaa aactgtgtag tcccgcgttc acaaccttca aaggctgatt aaataaggta
    23401 ttcatgcgtt tagccccttt ttctgcaact gagtctgtgc aacggtgctg gcccatagcg
    23461 ccgcctgtgc attgctgctg gcgatgatga cccctgcatt ttgtagtgcg cttatctgct
    23521 gactgcgtat ttgcggatca gcttccgttc cgcaaacgtg cgcaatcagc aacggagcgt
    23581 tattcatgtc gatgtgtgaa agttggtcca gtaattcgct ggcaggcgtc gtggaagcgc
    23641 cataaccaag taccaggtcg aataacacga cggcagtgtg tgagtcgttg agttcgttga
    23701 gcagacgttg attgcgcaga gtcgggtcga tcattggatg cggtttgcca cgggtgaaat
    23761 catcgtcgcc catatcgatc aacgtgtgat cttcgctttg ccagatattt gccagagcac
    23821 gattacccgc aactggcgta ttggaagctg cgctgaatcc cttttgttgg cagataagtt
    23881 gcgcttcgta gcagaaggtt cctccggcga aaacaccgcg tatcgcctgg cgatgggctg
    23941 gcaggcgctg gcaggcgttt tgtaacattg tgagatcgtc gcagggtaca tcggtttcga
    24001 cagccggaag tggctgagca ttcagtaacg ccacagcgat gtcggcggcg ctggcaagtg
    24061 tggtggcggc agtgatattg ggacgtgcca gatcatgcgg attcgccccg aggaaattca
    24121 ccaccacggg ttttccacaa gcctcggcgc gctccagaat agtccgggca acgatcggtg
    24181 aaggcggttt tgaaatcagc acaattacgc gagtttcatc gtcttgcgcc agcgcatcta
    24241 aagcgaagag catcgatatt ccaccaatct ctttactgag atcatgtccg cctgttccca
    24301 acgcctgaga aatacccgct ccgagctggt cgattcggca agtcacttcc tgtagcccgg
    24361 tgcctgacgc gccaataaca ccaattgctc cgcgtttcac cacattagcg aagcctaacg
    24421 gaatgccgtt aacaatggcg gttccacagt caggtcccat tacgatgcgc tgacgttctc
    24481 gggcaagcgt tttgatggat ttttcctgca cgatactgac gttatcgctg aacatcatca
    24541 cgttcattcc gaggtttaac gctttaattg cttcggcggc ggcgtagtct cccggtacag
    24601 aaatgagtgc caggttggct tcgggttcgg cttccagtgc catttccagg ctgacctttt
    24661 ccggtgtttt aatgccacta tccgtttcat catcgggttt gctggtcaga cgttgctggg
    24721 ccagtatcag tgcttcattg caaatatctt cttcacccat gactgcaatc actaaatcat
    24781 tgggactggc gttgatttcg ttacccagac ccgcatcgcg caattgttcg agattattgg
    24841 gcgttcccat gacgaccgag gcctgttgaa taccgggcaa cttgctgatt tgcgcggaaa
    24901 tctgcatcag agaaactgag tcctgataaa gattactgaa aactttatat ttaactttca
    24961 tgctgttacg cctgtttcat tccgcccgat agcaaaattc gggcaaagca tccccgtgta
    25021 gccccataaa cgggctacgg gagaaaaggt tgaaatcaat tcatggtgtt cagggttcga
    25081 aagccatgca gcattcctgc aaggcaatct actcctgacg ttgcgccaaa ttgcatgacc
    25141 tgttctgcac aggatgcgat tgtcattgcc gatgcgctcc caaccagttg tgcgagtaac
    25201 tggcaaatcg gttctgaaaa atgtccctga agcgcacgct ccagataatg acgactgata
    25261 tccgtggtgt tgtgcgcatg ttgatcaatt gcctgctgca accggtattg atgatcggca
    25321 agtggtgcag ggagttgcca taaccagagc gctgccagat agcccaacaa atagtcatct
    25381 ccatcgggcg ttaagccttt accaaagccg atcagttgtg gcacctggcg ttccagcgca
    25441 tctggatgct ccataatcgc taatccctgg tgcgtgagac tatccggcag gtgcaatgtg
    25501 ctttgaacgt tatgctccag acaaaataaa agccgttgcg atgccatcgt tgggtagtgc
    25561 tggaaaacca aagggaatgc ctcaagtgtc agcattcccc ccacaaatgg cgactgccag
    25621 agcgttgcgt tatcgagcgc cacacaaaat cgaggtgtcc gcagcaagcc tggggttaac
    25681 tgaatgggat ctgaatgggc aatctctctt cgccagtccc aacattcagg tagccagact
    25741 ctggcagcat cagggagatt cagatacgtt tgcgcacaca acagagtgat gaatgttccc
    25801 gcgtctgaat acagatttac cgcatgttta aaagcgctat gtagacgtaa atcttgcgtt
    25861 tcatcctgcg ggaaaagata tcccaacgac gatgcgcaaa gcgtaacctg taccatcggc
    25921 gttagccttc cagacctgca ataatggctt tggaatcagt aacccaaccg aaaatggcac
    25981 cttgtgcttt gatcatctcg agggcgtatt tctggaattc cgggaaatag gagccgacac
    26041 aatcttccgg gataatgcat tcatagccac gatcatttgc ttcgcgcacg gtggtggtta
    26101 cgcaaacttc ggttgttaca ccacaaacta tcagcgtctt gataccgtgg ttttgcaaaa
    26161 tcagatgtaa gtcggtttga taaaacgcgc ctttgccagg cttatcaatc accggttcgc
    26221 ctgccaccgg gtacagttca ggaatgatgt catgacctgc ttcacctctg accagaatgc
    26281 gtcccatcgg tcctggttca ccaataaagg tttttccgcc gcgcgtcagt ttggctggcg
    26341 ggcagtcgct taagtctgca cgatggcctt cacgagtatg aataaccata attccttttt
    26401 gacgtgcggc tgccagcacc tctgtacatg gtgcgatagc cgtgcgtacc cgtgaaacat
    26461 cattgcccag tgcctcaccg aagcccccgg cttcgacaaa gtcacgctgc atgtcgatca
    26521 tgaccagtgc agttgtgcgc ggatcaaaag gtaattcaaa gggttgagcc tgaaaaatgg
    26581 attgcgtcat ggtaaatctc ctgtctgatg tttaaacgat ccagttgttc tgagaacgag
    26641 tattcaggag aaaagcggca caaaacagga aaaaagtttg ccgcacagca acgaaatttt
    26701 tgcattcagc aggtggtgtg atgacgaatg tgaagggagt caaagagtgg catacagcaa
    26761 caaatttttt gatgctgtat ggttttgaga ttaaaaaaat cgttgaaatt gtgtgagctt
    26821 aatcatcaga tttagcgact atggcgttac tttttaacac catactgtgt aaaccattcc
    26881 aacattcgct gccagccgtc tttcgcagac tcggcatgat agctcggacg ataatcggcg
    26941 ttgaacgcat gctctgcatc cgggtacacg ataatctctg ctttcgcgtt tgctgcccgc
    27001 agcgcctggc gcatcgtttc cacactctct tgcggaatgc tgttatcctg gccgccatat
    27061 aagccgagaa ccggcgcgtt aagatcggtt gcgatatcaa caggttgttt cggtgaattc
    27121 agcgacttat cgcccgtcag tttgccgtac cacgccactg cggcttttag ctgtggatta
    27181 tgcgcggcat acagccaggt gatacgtcca ccccagcaga atccggtgat cattaaacga
    27241 tgaacatcgc cgccgttgcg ggaagcccaa ctggcgacat gatcgagatc ggccagcacc
    27301 tgcgagtcag gcacttttgc taccagaccg ccaagcaacg tggggatatc ggcaaaatca
    27361 ttcggatcgc cttcgcggaa gtaaagttca ggtgcgatag ccagataccc ctccagcgcc
    27421 agacggcgac aaatgtcgcg gatatgttca tgcacgccaa aaatttcctg cactacaatg
    27481 accactggca gtgggccatc gctttgcttt ggtctggcat ggtaagcagg catgttatcc
    27541 ccttgtgaag ggatagaggt gaagcccgcc acaatcgcgt cgtccggagt ctgaacgatg
    27601 gtcgaagcga gaggcgatgc agcaggtgca aatccagatt gttgtgttgt tgccatggta
    27661 ttctccgtac ccttataaaa atgttgcgca atgttaacta tagtcagcat gcaacaaatc
    27721 acattgcctg aatcggctca tcttttatgc agtcctgcag aatgaagagt gatttatgtg
    27781 atttgcatca cttttgatgg gtaaatttat gcaacacatt ttcgtcatgg tgatgagtat
    27841 cacgaaaaaa tgttaaaccc ttcggtaaag tgtctttttg cttcttctga ctaaaccgat
    27901 tcacagagga gttgtatatg tccaagtctg atgtttttca tctcggcctc actaaaaacg
    27961 atttacaagg ggctacgctt gccatcgtcc ctggcgaccc ggatcgtgtg gaaaagatcg
    28021 ccgcgctgat ggataagccg gttaagctgg catctcaccg cgaattcacc acctggcgtg
    28081 cagagctgga tggtaaacct gttatcgtct gctctaccgg tatcggcggc ccgtctacct
    28141 ctattgctgt tgaagagctg gcacagctgg gcattcgcac cttcctgcgt atcggtacaa
    28201 cgggcgctat tcagccgcat attaatgtgg gtgatgtcct ggttaccacg gcgtctgttc
    28261 gtctggatgg cgcgagcctg cacttcgcac cgctggaatt cccggctgtc gctgatttcg
    28321 aatgtacgac tgcgctggtt gaagctgcga aatccattgg cgcgacgact cacgttggcg
    28381 tgacagcttc ttctgatacc ttctacccag gtcaggaacg ttacgatact tactctggtc
    28441 gcgtagttcg tcactttaaa ggttctatgg aagagtggca ggcgatgggc gtaatgaact
    28501 atgaaatgga atctgcaacc ctgctgacca tgtgtgcaag tcagggcctg cgtgccggta
    28561 tggtagcggg ggttatcgtt aaccgcaccc agcaagagat cccgaatgct gagacgatga
    28621 aacaaaccga aagccatgcg gtgaaaatcg tggtggaagc ggcgcgtcgt ctgctgaaat
    28681 aaaaaaacgc tccccaactt cggggagcga tatcagttat tgacgccgta aacgcattat
    28741 tttgcggatt attggcgtca gtagcgtaaa ggctgccaga gtcagcaatg ccagagtgat
    28801 cggtcgggta tacagaaagt cgagtgaccc accagaaagc gacagcgcac ggcgaaaatt
    28861 actttccgcc attggcccca taatcaatgc cagcactacg ggtgatgccg gatatcctcc
    28921 tttctgcatg aaatagccca ccacgcctgc aatcagcata atgccaacat caaaaaggct
    28981 attgttcaac gcataagtcc cgaccacaca aagtgcgagg atcatcggtg tgagaatatt
    29041 gccgggaatt ttcaccacat taccgatgac tttcaaagag agcagtccaa gaactagtag
    29101 catgaagtaa cagaagatca tgccgacaaa cagtgtataa accatatcgc cgtggtcggt
    29161 aaacatcagc gggcctggtt gcattccctg taacgttaac gcgcccagca tgatggcggt
    29221 taccgcatcg ccagggatcc ccagcgtcag cataggtaac aatgcgccac cggtgcagcc
    29281 attcgcgcct gcctcacagg aggccacagc tttaatttca cccttaccaa agttttctgg
    29341 tgtcttactg aaacgacgag tttcgttata ggcaacaaaa gctgcaatat ccgcccccgc
    29401 accggggatc atgccgataa aaacccctaa tcctgatgag cgcaaaatgg ttaatgcgat
    29461 gcggcgtagt gtttgccagg gcagtaacag actgccgata gccaccttcg ccccctgacg
    29521 aatttgctgg ttttgctcca tagagcggaa tgcttctgaa gcagcaaata aaccaatcat
    29581 caccgggata aatggcacat tcatcagctc cacaaatcca cctgtaaacc gtggaaaacc
    29641 gcccattgga tcaaggccta tcgttgcgat cagcaatccg ccaaccccgg caatcagccc
    29701 cttaatcagc gactcaccgg aaatactggc aataatgctc agtccgaagg ttgccagggc
    29761 gaaggactcc gaggcactaa atttcagcgc ccaactggca agtaccggag agagaaacat
    29821 cagcacgata atgctgagcg ttccgccact aaaggaagag aacgtggcgg cactcaatgc
    29881 cagccctgct tttccctgct tcgtcagctc atatccgtca atggcggtgg ctgcggcggc
    29941 aggcgtaccg ggaattttga gcaaaattgc ggtgatagaa ccgccataga cgccgccaaa
    30001 aaagacgccg caaatcatca acaagccaga aacaggctcc atgccgtagg tgaaaggcag
    30061 caaaatcgcc acacccatgg tcgctgtcag accaggcaga gcgccaatca caatacccag
    30121 catcacccca aaagtggcaa acagcagcgc ctgaggatta ttgagtaatg tcgaaaaacc
    30181 ctgagttaaa agttcacttt caaacattgc tggcccctgt tattcgaaaa atgtgccgac
    30241 aggcaatggc acctgtaacg cttcgacaaa cagcaaccag aggattgccg ttaacagcag
    30301 cgcaataccc ggtgtgagta cccatcgcct gtagcccatc aacgtcataa tgacgatgag
    30361 gaaaacagga gtagtaatga gataaccgca gtagctcatc gccacaatat aaaacgcggt
    30421 tgccgcaatt cctgttgccg ttttcctgaa tgccggtttt tcctgtgcgt tggcgcaaga
    30481 ggctggtttt gcctgcaaaa gatcgcgtat caccagcaag acagcgagca caatcagggc
    30541 acaggcatag aaggtaggga aggcacttgc accgggatcc gtttcaatgg cagttgctgg
    30601 aaaatcagcg gcattaatca tcaccgcgcc agcaaccaca caaagtaaca gcgccaccac
    30661 catcgttgat gaaaggcgct tgcggtgcgg tacggcgagt tgagcaacag actgttttgt
    30721 gttcatcaac cgtacctcag gtttattttt tcaggcccag gcgagtcagc aactcgtcaa
    30781 agtacttttc ctgttcgctg atttgggtct ggaagctggc agcgtcaagc catgcatagt
    30841 tgagattcaa cttttgtagt gcatcctgga atgcaggctc ttcagccgtc tcttttgctg
    30901 cctttgccag aacatccacc acatcctgcg gcgttttttg cgacacaatc aggccgcgcc
    30961 aggtgccgat ggagagatca acgcctttct cttttaacgt cgggacgtca ggcatggttt
    31021 tcattcgctc atccgccatc actaccagtg tcttcagctt gccgcctttc acatggttga
    31081 taacttctcc tgggcttacg gaaaccgctt caatgtgccc gcctaacagg cctgtaatgg
    31141 caggggctgc gccgtcatac gggacatgag aaaactttgc gcccgttttg tcttccagtg
    31201 cagctgccgc cagatgccag atagctccgg tgcctgagtt accaatgcgt acttttccgg
    31261 gattcgcttt ggcgtaagtc ataaattctt catagctatt ccacggcgca tcggcacgga
    31321 ctgtgatagc agccggatcc gcattcagac gggcaatggg tttaaagtcg ctggttttaa
    31381 aacgcaccat tccgaggctg ggaagggtgg tcagttcaac cgtgcctaaa ccaattttgt
    31441 aaccgccagg gcgggcagcg gcgatttcac tcaggccgat agcaccgcct ccgccaggtt
    31501 tattgataac cccgatgctg acgggtaaat ggtttttggc ggcatcagca aaggcacggg
    31561 caaccagatc cgtaccgcct ccggcagcgt agggaacgac taactcgatc tgtttggttg
    31621 gccaggaggc agcctgtaca ggcgcaatgc tgagggcagc gcctgcaaga agtaccattg
    31681 cagccatttt tttcggtaag gtaagatgtt ttatcattgc ttttatatcc ttatttatca
    31741 gttagttgct atttaaattg ttccatgcgt tcataaacag tactgcattt tcatagactt
    31801 gctctggcgt catgccgggg tgatatagcg cagaaccgag gccaaagccg tttgcgccgt
    31861 ggctcagata acgcgccatg gtttccggtg tgataccgcc aaccggtaac atcggaacgg
    31921 attgtggaat aaccgcacgc caggctttgg taacttctgg cgtaatttgt tcagccggga
    31981 acagcttgat ggcattagca ccatgttcaa tggcagtaaa ggcttcggtg ggcgtggcga
    32041 cgccaggcgc acaatacata cccagcgcac gggcgcgacg gatcaccgca gtatcgcaat
    32101 gcggcatcac gataatctgg cccccagcct ctttaaccgc aaccacctgc tctaccgaaa
    32161 gcacagttcc ggctccgacc aggcagtcct taggcagggc gtcgcgcagt aaactgatac
    32221 tttgcaacgc ctccggcgag ttcataggaa tctcaatcag gcggaatccg gcggcgtaca
    32281 gtttttcacc gatggcgaca atctcatccg gtttcacgcc gcgtaaaatg gcgactaacc
    32341 cggttttttg caaaagcgta ttaaatggca tgggtacatt ccctggcgtt ggtggacagt
    32401 aacccggcag cgtgggcgat tcgccataat ccctgttcag tggcattagg aatggcgtgt
    32461 atctgtctgt cgggaaaaac gtggctgaat gcttgtgaat agcggctgtt cagatttgcg
    32521 ctaccgatta aggcgatcgg tgttgtggcg ggtaaatcac gtagcaaact ggatgccaga
    32581 ccacataatt catggcctat cagtaatccg gaaaggtaat ccccctgcga ggacgacgta
    32641 agattactgg tcagcaggcg cgaacgggtc gaaaacagcg tcgataataa tccggtctga
    32701 tgatgctctt gtgctgctgt cagcccgtgg gtgaaggcat cccagtgcag ttcatctcca
    32761 ggatgcatgg tggcaccgag aatcgaatgg cgggataaaa catcaaataa ctcgcccgtc
    32821 ataaaggttc ggaaatcggt aatggtgttg ttttcaacta ctgcccattt cgcatgtgtg
    32881 ccgggtaagc ctatcagcac tggcataccc tgatggatcg cattttgcag ggacggttcc
    32941 atcgagatag caccgaagat ttgtgtctct tcgccacgca tcacttcggg catttcacct
    33001 tctttaatca cgccaggaat gatgtgcagc attgtctgct gctggtggat aacaggcgtc
    33061 aactgcttcg ccagaccctc gagagtgacc gggcaaggta aataagctgc tggttgccac
    33121 ccttgcgcac tgccgagcat gccgcaagcc agtaccgggc atggggtttg tgccagccag
    33181 tcgccgcaga cacgtaaaaa cgtatcgtgg aaagcgtcct cacgtgttgc tgcctgggag
    33241 ggtaatttca tgatccccca ggggaattca cgtttttctt gtggatttgg tgattcgcca
    33301 aaacgccatg cccgaagcga tgacgttccc cagtccaggg caataaatga gggtgctccc
    33361 ggcattagtc gtttccttta atcatggttt atttatcttt gcggacgtgc ttaccccagc
    33421 ccagttcagc ggatatctct tctgcacagg atttgacgta aggtgccagt tcttccagac
    33481 gcgccagcga catatacgtg gtggtactgg cgacagaaat agccgccaca atttcatccc
    33541 gggcgttgta aaccggcgct gcaacgcaac ggatagtcgg ctcgttctct tccagatcaa
    33601 aagcaaaacc actggcggca taacgacgca tgttctgaat aaatgcgccc agttttgttt
    33661 catcaccaca ggtcttaaac agcgtgcgcc actcttcttc tgttcggttg aggatcaatg
    33721 ccttgccgat gccggtgatt gccagtggca tgcgatggcc tgggcgtgag cgcatttcca
    33781 gcccgcgctg actgttgatc ttctccagat acagcacttc gtcgccttca acgatcccca
    33841 gatgcacggt gtccagggtg taacgggcaa ggcgttgcaa aacgggctgg gcaatttcgt
    33901 acagcgaggt gctttccagt gctctggcac cgaattcgat cagtttggca cccagttggt
    33961 agccctgcgt tgggacatgg cgcaggtagc gttgttccac cagaacggtg actaaacgat
    34021 gggttgtgct ccgggtcgtg ccggtgaact cgccgatact ttttaggtca tggcagccgt
    34081 tataaacagc attaagaacc gccagtccac gtaataacgt ttgtgcgcct gcggtggttg
    34141 aagaggtttc tgccatacgt ttctcctgat gatattgctg aagtgttcca cataatgacg
    34201 tggggaaaag gtgatatatc ccacaatata aacttcatct catattatgg gataaaataa
    34261 tgaaaattaa cgatcgtttt gcgtagcgcc tcgcaggaaa cttctttcaa actggacgtt
    34321 tgtacagcac aattctattt tgtgcgggta agttgttgcg tcaggaggcg ttgtggattt
    34381 ctcaatcatg gtttacgcag tcattgcgtt ggtgggtgtg gcaattggct ggctgtttgc
    34441 cagttatcaa catgcgcagc aaaaagccga gcaattagct gaacgtgaag agatggtcgc
    34501 ggagttaagc gcggcaaaac aacaaattac ccaaagcgag cactggcgcg cagagtgtga
    34561 attgctcaat aacgaagtgc gcagcctgca aagtattaac acctcgctgg aggccgatct
    34621 gcgtgaagtg accacgcgga tggaagccgc acagcaacac gctgacgata aaattcgcca
    34681 gatgatcaac agcgaacagc gcctcagtga gcaatttgaa aaccttgcca accgtatttt
    34741 tgaacacagt aatcgtcggg ttgatgagca aaatcgccag agtctgaaca gtcttttgtc
    34801 gccgttgcgt gaacaactgg acggttttcg ccgtcaggtt caggacagtt tcggtaaaga
    34861 agcacaagaa cgtcataccc tgactcacga aatccgcaat ctccagcaac tcaacgcgca
    34921 aatggcccag gaagcgatca acctgacgcg tgcgctgaaa ggcgacaata aaacccaggg
    34981 caactggggc gaagtggtgc taacccgcgt actggaggcg tctggtctgc gtgaagggta
    35041 tgaatatcag actcaagtga gtatcgaaac cgacactcgt tcgcgaatgc aaccggatgt
    35101 catcgtgcgg ctgccgcagg gcaaagatgt ggtgatcgac gccaaaatga cgctggttgc
    35161 ctatgaacgt tatttcaacg ctgaagatga ctacacacgt gaaagcgcgc tacaggaaca
    35221 tatcgcgtcg gtgcgtaacc atatccgttt gctgggacgc aaagattatc aacagctgcc
    35281 ggggctgcga actctggatt acgtgctgat gtttattccc gttgaacccg cttttttact
    35341 ggcgcttgac cgtcagccgg agctgatcac cgaagcgttg aaaaacaata tcatgctggt
    35401 tagcccgact acgctgctgg tggcgctgcg cactatcgcc aacctgtggc gttatgagca
    35461 tcaaagccgc aacgcccagc aaatcgccga tcgtgccagc aagctgtacg acaagatgcg
    35521 tttgttcatc gatgacatgt ccgcgattgg tcaaaatctc gacaaagcgc aggataacta
    35581 tcgccaggca atgaaaaaac tctcttcagg tcgcggaaat gtgctggcgc aggcagaagc
    35641 gtttcgcggt ttaggggtag aaattaaacg cgagattaat ccggatttgg ctgaacaggc
    35701 ggtgagccag gatgaagagt atcgacttcg gtcggttccg gagcagccga atgatgaagc
    35761 ttatcaacgc gatgatgaat ataatcagca gtcgcgctag cccattgggg gtagttaagc
    35821 cgggtagaaa tctagggcat cgacgcccaa tctgttacac ttctggaaca attttttgat
    35881 gagcaggcat tgagatggtg gataagtcac aagaaacgac gcactttggt tttcagaccg
    35941 tcgcgaagga acaaaaagcg gatatggtcg cccacgtttt ccattccgtg gcatcaaaat
    36001 acgatgtcat gaatgatttg atgtcattcg gtattcatcg tttgtggaag cgattcacga
    36061 ttgattgcag cggcgtacgc cgtgggcaga ccgtgctgga tctggctggt ggcaccggcg
    36121 acctgacagc gaaattctct cgcctggtcg gagaaactgg caaagtggtc cttgctgata
    36181 tcaatgaatc catgctcaaa atgggccgcg agaagctgcg taatatcggt gtgattggca
    36241 acgttgagta tgttcaggcg aacgctgagg cgctgccgtt cccggataac acctttgatt
    36301 gcatcaccat ttcgtttggt ctgcgtaacg tcaccgacaa agataaagca ctgcgttcaa
    36361 tgtatcgcgt gctgaaaccc ggcggccgcc tgctggtgct tgagttctcg aagccaatta
    36421 tcgagccgct gagcaaagcc tatgatgcat actccttcca tgtgctgccg cgtattggct
    36481 cactggtcgc gaacgacgcc gacagctacc gttatctggc agaatccatc cgtatgcatc
    36541 ccgatcagga taccctgaaa accatgatgc aggatgccgg attcgaaagt gttgactact
    36601 acaatctgac ggcaggggtt gtggcgctgc atcgtggtta taagttctga caggagaccg
    36661 gaaatgcctt ttaaaccttt agtgacggca ggaattgaaa gtctgctcaa caccttcctg
    36721 tatcgctcac ccgcgctgaa aacggcccgc tcgcgtctgt tgggcaaagt gctgcgcgtg
    36781 gaggtaaaag gcttttcgac gtcattgatt ctggtgttca gcgaacgcca ggtcgatgta
    36841 ctgggcgaat gggcaggcga tgctgactgc accgttatcg cttacgccag cgtgttgccg
    36901 aaacttcgcg atcgccagca gcttgccgca ctgattcgta gtggtgagct ggaagtgcag
    36961 ggcgatattc aggtggtgca aaacttcgtt gcgctggcag atctggctga gttcgaccct
    37021 gcggaactgc tggcccctta taccggtgat atcgccgctg aaggtatcag caaagccctg
    37081 cgcgggggcg caaagttcct gcatcacggc attaagcgcc agcaacgtta tgtggcggaa
    37141 gccattactg aagagtggcg tatggcaccc ggtccgcttg aagtggcctg gtttgcggaa
    37201 gagacggctg ccgtcgagcg tgctgttgat gccctgacca aacggctgga aaaactggag
    37261 gctaaatgac gccaggtgaa gtacggcgcc tatatttcat cattcgcact tttttaagct
    37321 acggacttga tgaactgatc cccaaaatgc gtatcaccct gccgctacgg ctatggcgat
    37381 actcattatt ctggatgcca aatcggcata aagacaaacc tttaggtgag cgactacgac
    37441 tggccctgca agaactggga ccagtatgga tcaagttcgg gcagatgtta tcaacccgcc
    37501 gcgatctttt tccgccgcat attgccgatc agctggcgtt attgcaggac aaagtcgctc
    37561 cgtttgatgg caagctggcg aagcagcaga ttgaagctgc aatgggcggc ttgccggtag
    37621 aagcgtggtt tgacgatttt gaaatcaagc cgctggcttc tgcttctatc gcccaggttc
    37681 ataccgcgcg attgaaatcg aatggtaaag aggtggtgat taaagttatc cgcccggata
    37741 ttttgccggt cattaaagcg gatctgaaac ttatctaccg tctggctcgc tgggtgccgc
    37801 gtttgctgcc ggatggtcgc cgtctgcgcc caaccgaagt ggtgcgcgag tacgaaaaga
    37861 ccttgattga tgaactgaat ttgctgcggg aatctgccaa cgccattcag cttcgacgca
    37921 attttgaaga cagcccgatg ctctacatcc cggaagttta ccctgactat tgtagtgaag
    37981 ggatgatggt gatggagcgt atttacggca ttccggtgtc tgatgttgcg acgctggaga
    38041 aaaacggcac caacatgaaa ttgctggcgg aacgcggcgt gcaggtgttc ttcactcagg
    38101 tctttcgcga cagctttttc catgctgata tgcaccctgg caacatcttc gtaagctatg
    38161 aacacccgga aaacccgaaa tatatcggca ttgattgcgg gattgttggc tcgctaaaca
    38221 aagaagataa acgctatctg gcggaaaact ttatcgcctt ctttaatcgc gactatcgca
    38281 aagtggcaga gctacacgtc gattctggtt gggtgccacc agataccaac gttgaagagt
    38341 tcgaatttgc cattcgtacg gtctgtgaac ctatctttga gaaaccgctg gccgaaattt
    38401 cgtttggaca tgtactgtta aatctgttta atacggcgcg tcgcttcaat atggaagtgc
    38461 agccgcaact ggtgttactc cagaaaaccc tgctctacgt cgaaggggta ggacgccagc
    38521 tttatccgca actcgattta tggaaaacgg cgaagccttt cctggagtcg tggattaaag
    38581 atcaggtcgg tattcctgcg ctggtgagag catttaaaga aaaagcgccg ttctgggtcg
    38641 aaaaaatgcc agaactgcct gaactggttt acgacagttt gcgccagggc aagtatttac
    38701 agcatagtgt tgataagatt gcccgcgagc ttcagtcaaa tcatgtacgt cagggacaat
    38761 cgcgttattt tctcggaatt ggcgctacgt tagtattaag tggcacattc ttgttggtca
    38821 gccgacctga atgggggctg atgcccggct ggttaatggc aggtggtctg atcgcctggt
    38881 ttgtcggttg gcgcaaaaca cgctgatttt ttcatcgctc aaggcgggcc gtgtaacgta
    38941 taatgcggct ttgtttaatc atcatctacc acagaggaac atgtatgggt ggtatcagta
    39001 tttggcagtt attgattatt gccgtcatcg ttgtactgct ttttggcacc aaaaagctcg
    39061 gctccatcgg ttccgatctt ggtgcgtcga tcaaaggctt taaaaaagca atgagcgatg
    39121 atgaaccaaa gcaggataaa accagccagg atgctgattt tactgcgaaa actatcgccg
    39181 ataagcaggc ggatacgaat caggaacagg ctaaaacaga agacgcgaag cgccacgata
    39241 aagagcaggt gtaatctgtg tttgatatcg gttttagcga actgctattg gtgttcatca
    39301 tcggcctcgt cgttctgggg ccgcaacgac tgcctgtggc ggtaaaaacg gtagcgggct
    39361 ggattcgtgc gttgcgttca ctggcgacaa cggtgcagaa cgaactgacc caggagttaa
    39421 aactccagga gtttcaggac agtctgaaaa aggttgaaaa ggcgagcctc actaacctga
    39481 cgcccgaact gaaagcgtcg atggatgaat tacgccaggc tgcggagtcg atgaagcgtt
    39541 cctacgttgc aaacgatcct gaaaaggcga gcgatgaagc gcacaccatc cataacccgg
    39601 tggtgaaaga caatgaaact gtgcatgaag gcgtaacgcc tgctgctgca caaacgcagg
    39661 ccagttcgcc ggaacagaag ccagaaacca cgccagagcc ggtggtaaaa cctgctgcgg
    39721 acgctgaacc gaaaaccgct gcaccttccc cttcgtcgag tgataaaccg taaacatgtc
    39781 tgtagaagat actcaaccgc ttatcacgca tctgattgag ctgcgtaagc gtctgctgaa
    39841 ctgcattatc tcggtgatcg tgatattcct gtgtctggtc tatttcgcca atgacatcta
    39901 tcacctggta tccgcgccat tgatcaagca gttgccgcaa ggttcaacga tgatcgccac
    39961 cgacgtggcc tcgccgttct ttacgccgat caagctgacc tttatggtgt cgctgattct
    40021 gtcagcgccg gtgattctct atcaggtgtg ggcgtttatc gccccagcgc tgtataagca
    40081 tgaacgtcgc ctggtggtgc cgctgctggt ttccagctct ctgctgtttt atatcggcat
    40141 ggcgttcgcc tactttgtgg tctttccgct ggcatttggc ttccttgcca ataccgcgcc
    40201 ggaaggggta caggtatcca ccgacatcgc gagctattta agcttcgtta tggcgctgtt
    40261 tatggcgttt ggtgtctcct ttgaagtgcc ggtggcaatt gtgctgctgt gctggatggg
    40321 gattacctcg ccagaagact tacgcaaaaa acgcccgtat gtgctggttg gtgcattcgt
    40381 tgtcgggatg ttgctgacgc cgccggatgt cttctcgcaa acgctgttgg cgatcccgat
    40441 gtactgcctg tttgaaatcg gtgtcttctt ctcacgcttt tacgttggta aagggcgaaa
    40501 ccgggaagag gaaaacgacg ctgaagcaga aagcgaaaaa actgaagaat aaattcaacc
    40561 gcccgtcagg gcggttgtca tatggagtac aggatgtttg atatcggcgt taatttgacc
    40621 agttcgcaat ttgcgaaaga ccgtgatgat gttgtagcgc gcgcttttga cgcgggagtt
    40681 aatgggctac tcatcaccgg taccaatctg cgtgaaagcc agcaggcgca aaagctggcg
    40741 cgtcagtatt cgtcctgttg gtcaacggcg ggcgtacatc ctcacgacag cagccagtgg
    40801 caagctgtga ctgaagaagc gattattgag ctggccgcgc agccagaagt ggtggcgatt
    40861 ggtgaatgtg gtctcgactt taaccgcaac ttttcgacgc cggaagagca ggaacgcgct
    40921 tttgttgccc agctacgcat tgccgcagaa ttaaacatgc cggtatttat gcactgtcgc
    40981 gatgcccacg agcggtttat gacattgctg gagccgtggc tggataaact gcctggtgcg
    41041 gttcttcatt gctttaccgg cacacgcgaa gagatgcagg cgtgcgtggc gtgtggaatt
    41101 tatatcggca ttaccggttg ggtttgcgat gaacgacgcg ggctggagct gcgggaattg
    41161 ttgccgttga ttccggcgga gaaattgctg atcgaaactg atgcgccgta tctgctccct
    41221 cgcgatctca cgccaaagcc atcatcccgg cgcaacgcgc cagcccatct gccccatatt
    41281 ttgcaacgta ttgcgcactg gcgtggagaa gatgccgcat ggctggctgc caccacggat
    41341 gccaatgtca aaacactgtt tgggattgcg ttttagagtt tgcggaactc ggtgttcttt
    41401 acgctgtgct taatttcttt attgataaga ttaagcaata gcatggagcg agcctctccg
    41461 tctggctcgg tgaaaatggc ctgaaaacct tcgaatgcgc cttcagtaat aatcacttta
    41521 tcaccaggat acggcgtcga tggatcgaca atatctttcg gtttatacac tgataactga
    41581 tgaatcaccg ccgatgggac tatcgctggc gacgcgccaa agcgcacgaa gtggctgaca
    41641 ccgcgggtcg cgttgatagt cgtggtatga atcacttccg gatcgaactc cacaaacaag
    41701 tagttgggga acaatggctc actgactgca gtacgtttgc cacgcacgat tttttccagg
    41761 gtgatcatcg gtgccaggca attcacagcc tgtctttcga ggtgttcctg ggcacgttga
    41821 agttgcccgc gcttgcagta cagtaaatac caggattgca taatgactct tatccgttta
    41881 atcggggcgc aaggatagca aaagctttac gctaagttaa ttatattccc cggtttgcgt
    41941 tataccgtca gagttcacgc taatttaaca aatttacagc atcgcaaaga tgaacgccgt
    42001 ataatgggcg cagattaaga ggctacaatg gacgccatga aatataacga tttacgcgac
    42061 ttcttgacgc tgcttgaaca gcagggtgag ctaaaacgta tcacgctccc ggtggatccg
    42121 cacctggaaa tcactgaaat tgctgaccgc actttgcgtg ccggtgggcc tgcgctgttg
    42181 ttcgaaaacc ctaaaggcta ctcaatgccg gtgctgtgca acctgttcgg tacgccaaag
    42241 cgcgtggcga tgggcatggg gcaggaagat gtttcggcgc tgcgtgaagt tggtaaatta
    42301 ttggcgtttc tgaaagagcc ggagccgcca aaaggtttcc gcgacctgtt tgataaactg
    42361 ccgcagttta agcaagtatt gaacatgccg acaaagcgac tgcgtggtgc accctgccaa
    42421 caaaaaatcg tctctggcga tgacgtcgat ctcaatcgca ttcccattat gacctgctgg
    42481 ccggaagatg ccgcgccgct gattacctgg gggctcaccg taacgcgtgg cccgcataaa
    42541 gagcggcaga atctgggcat ttatcgccag cagctaattg gtaaaaacaa actgattatg
    42601 cgctggctgt cgcatcgcgg cggcgcgttg gattatcagg agtggtgtgc ggcgcatccg
    42661 ggcgaacgtt tcccggtttc tgtggcgctg ggtgccgatc ctgccacgat tctcggtgca
    42721 gtcacccccg ttccggatac gctttcagag tatgcgtttg ccggattgct gcgcggtacc
    42781 aagaccgaag tggtgaagtg tatctccaat gaccttgaag tgcccgccag tgcggagatt
    42841 gtgctggaag ggtatatcga acaaggcgaa actgcgccgg aagggccgta tggcgaccat
    42901 accggttact ataacgaagt cgatagtttt ccggtattta ccgtgacgca tattacccag
    42961 cgtgaagatg cgatttatca ttccacctat accgggcgtc cgccagatga acctgcggta
    43021 ctgggtgtag cactgaacga agtgttcgtg ccgattctgc aaaaacagtt cccggaaatt
    43081 gtcgattttt atctgccgcc ggaaggctgt tcttatcgtc tggcggtagt gacgatcaaa
    43141 aaacagtacg ccggacacgc gaagcgcgtc atgatgggcg tctggtcgtt cttacgccag
    43201 tttatgtaca ctaaatttgt gatcgtttgc gatgatgacg tcaacgcccg cgactggaac
    43261 gatgtgattt gggcgattac cacccgtatg gacccggcgc gggatactgt tctggtagaa
    43321 aatacgccta ttgattatct ggattttgcc tcgcctgtct ccgggctggg ttcaaaaatg
    43381 gggctggatg ccacgaataa atggccgggt gaaacccagc gtgaatgggg acgtcccatc
    43441 aaaaaagatc cagatgttgt cgcgcatatt gacgccattt gggatgaact ggctattttt
    43501 aacaacggta aaagcgcctg atgcgcgttt gttttgccct atttatcgat ccgacagaga
    43561 aagcgcatga caaccttaag ctgtaaagtg acctcggtag aagctatcac ggataccgta
    43621 tatcgtgtcc gcatcgtgcc agacgcggcc ttttcttttc gtgctggtca gtatttgatg
    43681 gtagtgatgg atgagcgcga caaacgtccg ttctcaatgg cttcgacgcc agatgaaaaa
    43741 gggtttatcg agctgcatat tggcgcttct gaaatcaacc tttacgcgaa agcagtcatg
    43801 gaccgcatcc tcaaagatca tcaaatcgtg gtcgatattc cccacggaga agcgtggctg
    43861 cgcgatgatg aagagcgtcc gatgattttg attgcgggcg gcaccgggtt ctcttatgcc
    43921 cgctcgattt tgctgacagc gttggcgcgt aacccaaacc gtgatatcac catttactgg
    43981 ggcgggcgtg aagagcagca tctgtatgat ctctgcgagc ttgaggcgct ttcgttgaag
    44041 catcctggtc tacaagtggt gccggtggtt gaacaaccgg aagcgggctg gcgtgggcgt
    44101 actggcaccg tgttaacggc ggtattgcag gatcatggta cgctggcaga gcatgatatc
    44161 tatattgccg gacgttttga gatggcgaaa attgcccgtg acctgttttg cagcgagcgt
    44221 aatgcgcggg aagatcgcct gtttggcgat gcgtttgcat ttatctgaga tataaaaaac
    44281 ccgcccctga caggcgggaa gaacggcaac taaaacttta tacagtggca ttactctacg
    44341 ttgcatccgg caaacagtgc ccgatgcaac gctgccgcgt cttatcgggc ctacaaaagt
    44401 tctgaaccgt gggccggata aggcgttcac gccgcatccg gcaagtggtt aaacccgctc
    44461 aaacaccgtt gcaatgccct gacccagacc gatacacatc gtcgccagac caaactggac
    44521 gtctttgtgt tccatcagat tcagcagcgt ggtgctgata cgcgcaccgg aacaacccag
    44581 cggatgaccc agcgcgatcg cgccaccgtt gaggttgatc ttctcgtcaa tctgctccat
    44641 tagcccgaga tctttaatac acggcaggat ctgcgcggca aaggcttcgt tcatctcgaa
    44701 tacgccgata tcgctggcag aaagccccgc ttttttcagc gccagcttcg aggccggaac
    44761 cggaccataa cccataatag atgggtcaca acccacaacc gccatcgaac gcacgcgggc
    44821 gcgcggctta agacctaatt cacgggcgcg gctttcactc atcaccagca tggcagctgc
    44881 gccatcggaa agcgcagaag atgtacccgc cgttaccgta ccgctgacgg gatcaaacgc
    44941 cggacgcagt gtggcgaggg cttccacggt ggtttccggg cgaatcactt cgtcgtaatt
    45001 aaactgcttc aatacgccgt cggcatcgtg accaccggtc gggatgattt catttttaaa
    45061 tgcgcctgac tgcgtggcgg cccacgcgcg ggcgtgtgac cgcgcggcaa aggcatcctg
    45121 catttcacgg ctgataccgt gcatacgcgc cagcatttct gccgttaagc ccatcatgcc
    45181 cgccgctttg gcgacattac ggctcaggcc ggggtgaaaa tcgacgccgt gactcattgg
    45241 cacatggccc atatgctcca cgccgccaac cagacatgcc tgcgcatcac cggtcatgat
    45301 cattcgtgct gcgtcatgca gtgcctgcat ggatgaacca cacaagcgat taacggtaac
    45361 cgccgggaca gagtgcggca cttcagccaa cagtgccgcg ttacgggcga tattaaaacc
    45421 ctgctccagt gtttgctgca cacaacccca gtaaatatcg tcaagggccg ccgcttccag
    45481 tgccgggtta cgcgccagca ggctacgcat taaatgagcg gagagatctt ccgcacgcac
    45541 gttacgaaaa gcaccgccct tcgaacggcc catcggggtg cgaattgcat cgacaatgac
    45601 aacctgttcc attgtgactc cttaagccgt tttcaggtcg ccaaccggac gggctggctc
    45661 aaccggggga tagtacggtt cgttatgacg tgctttatta cgcagacctt ccggtacttc
    45721 atacagcggg ccgaggtgct gatattgctg tgccatatcg aggtattttg cgctgccgag
    45781 ggtgtccagc cagcggaacg cgccgccgtg gaacggaggg aagcccaggc cgtagaccag
    45841 cgccatatcc gcttctgccg gagtggcgat aatgccctct tccagacagc ggaccacttc
    45901 gttgaccatc gggatcatca tgcgggcgat aatctcttct tcgctgaaat cgcgcttcgg
    45961 ctggctcact tttgccagca ggtcgtcaac gacgacatct tcttctttct tcggcttacc
    46021 tttgctgtct tctttataac gccagaaacc gaggccgttc ttctgaccaa agcggttggc
    46081 atcaaacagc gcgtcgatgg catcgcgata atctttctgc atccgctgcg ggaagcctgc
    46141 tgccatgaca gcctgggcgt gatgcgcggt gtcaatgccc acaacatcca gcagatatgc
    46201 cggacccatc ggccagccaa actgtttttc catcactttg tcgatcttgc ggaaatccgc
    46261 gccgtcgcgc agcaactggc tgaaaccggc gaaatagggg aacagtacac ggttgacgaa
    46321 gaagccgggg cagtcgttaa ccacaatcgg cgttttgccc atcttgctcg cccaggcgac
    46381 gactttcgcg atggtttcgt cggagctttt ctcgccgcga ataatttcta ccaacggcat
    46441 tcggtggacc gggttaaaga agtgcatccc gcagaagttt tccggacgtt ccagcgcgtt
    46501 ggccagttcg ctgataggaa tggttgaagt gttcgacgcc agtacggtat ccgggcgtac
    46561 tttctgctcg gtttctgcca gcacggcttt tttcactttc gggttttcaa caaccgcttc
    46621 taccacaaca tccacgcggt caaacccggc gtagtcgagc gttgggtgaa ttgtggagat
    46681 cacgccagcc agtttcagac catcgatctt gccgcgctca agctgcttgt tcagcagttt
    46741 cgcggcttcg gtcatgccga gggttaacga cttgtcgttg atatctttca tgacaaccgg
    46801 cacgcctttc cacgcagact ggtaagcgat gccgccgccc ataatgcctg cgcccagcac
    46861 agcggcctgt ttcggggttt caacatcttt ggtgagtttc ttcgctttac cttttacata
    46921 ttgatcgtta aggaaaatgc cgaccagtgc gcgggcttcg ttggtatgcg ccagcgggac
    46981 aaaacttttg ttttccaggt ttaaggcttc ttcacgacca aaacgggccg cagcttcaat
    47041 ggtttttact gcggtgatgg gggccggata atgtttcccc gccgtttgtg cgaccatccc
    47101 tttagcgatg gtgaagctca tggtggcttc aatcttgctc agttttagcg gttccagctt
    47161 cggctgacgt ttcgctttcc agtcgaggtc gccgttaatg gcctggcgta aaatcgccat
    47221 cgccccttca atcagttttt ctgctttgac tacaccatcc accagaccga ttttcagcgc
    47281 ctgatccgcg ccgacatctt taccggcggc aatgatttcc agcgcactgt cagcgcccag
    47341 catacgtggc atacgtacag aaccgccaaa gcccggcatg atgcccagtt tggtttccgg
    47401 cagaccgatg cgcagatccg gcgtcgccag acgataatcg gtcgccagca cgcattcgca
    47461 gccaccgccc agcgcatagc cgttgacggc agcaatggtc ggcaccggga gatcttccag
    47521 gcgattaaac acgctattgg caaagtgcag ccactgactt aactgttctt caggaacgag
    47581 gaacagggac aaaaattcgg tgatatcagc accgacgata aaggctgctt tgttcgaacg
    47641 cagcagcagc ccttttagat ctgattgctg ttccagcacg ccgatggcct cgccgaggct
    47701 ggcgacggtc gcagtgtcga gtttattaac tgaacctggg gcatcaaata ccagttcggc
    47761 aatgccatct tccagccagt caaggtacag ggtgtcgcct ttgtaaagca tgtcagtctc
    47821 ctgaatccgc aaggtgatct ggtcgtacca gatgcatcga agtgtgtatt ttgtgttaaa
    47881 aatatgcaaa taaaagatta aagaaatgcc gatctgatca cgctcggcag aaatcacgct
    47941 ctggatgaac gatgtgctaa gatgcggaga cttaaggtca aaaaaacaga agggtaaaaa
    48001 atggaatcac tggcctcact ctataaaaat catatcgcta ccttacaaga acggactcgc
    48061 gatgcgctgg cgcgcttcaa gctggatgcg ttacttattc actccggcga actgttcaac
    48121 gtttttctcg acgatcatcc ctatccgttt aaagtgaacc cgcaattcaa agcgtgggtg
    48181 ccggtaactc aggtgccaaa ctgctggctg ctggtggatg gcgtgaacaa gccgaaactg
    48241 tggttttatc tgccggttga ttactggcac aacgtcgaac cgctaccgac ctccttctgg
    48301 actgaagatg tagaagtgat cgcgctgccg aaagccgatg gcattggtag cctgctgcct
    48361 gctgcgcgcg gcaatatcgg ttatatcggt ccggtgccgg aacgtgcgct gcaactgggt
    48421 attgaggcca gcaacatcaa cccgaaaggg gtgatcgact acctgcatta ctaccgctcc
    48481 ttcaaaaccg agtacgaact ggcctgtatg cgtgaagcgc agaaaatggc ggtcaatggt
    48541 catcgtgcgg cagaagaagc gttccgttct ggcatgagcg agttcgatat caacattgcc
    48601 tatctgaccg cgaccggtca tcgtgatacc gacgtacctt atagcaacat tgtggcgctt
    48661 aacgaacacg ctgcggtgtt gcattacacc aaactggacc accaggcacc ggaagagatg
    48721 cgcagcttcc tgctggatgc cggggccgaa tataacggct atgcggctga tctgacccgt
    48781 acctggtcgg caaaaagcga caacgactac gcacagctgg tgaaagacgt aaatgatgag
    48841 caactggcgc tgatcgccac catgaaagca ggcgtcagct atgtggatta ccatatccag
    48901 ttccatcagc gcatcgccaa actgctgcgt aaacatcaaa tcatcaccga tatgagtgaa
    48961 gaagcgatgg tcgaaaacga tctcaccgga ccgtttatgc cgcacggtat cggccatccg
    49021 ctgggcctgc aggtgcatga cgtagccggt tttatgcagg atgatagcgg tacgcacctc
    49081 gcggcaccgg caaaatatcc gtacctgcgc tgcacccgta ttctccagcc gggcatggtg
    49141 ttaaccatcg aaccgggtat ctacttcatc gaatcgctgc tggcaccgtg gcgtgaaggg
    49201 cagttcagca aacacttcaa ctggcagaaa attgaagcac tgaaaccgtt cggcggcatt
    49261 cgtatcgaag acaacgtggt gattcacgaa aacaacgtgg aaaacatgac ccgggatctg
    49321 aaactggcgt gatggaaagc tggttaattc ctgcggcacc ggtcacggtc gttgaagaga
    49381 tcaaaaagag ccgcttcatt acgctgttgg cgcataccga tggcgttgag gcggcaaaag
    49441 cgtttgttga atcggtgcgg gcagaacacc ccgatgcccg ccaccattgc gtggcgtggg
    49501 tggcgggtgc gccggatgat tctcaacagc tgggtttctc tgacgacggg gagccggcgg
    49561 gaacggcagg taaaccgatg ctcgcccaac taatgggcag cggcgtcggg gaaattaccg
    49621 ctgtggtggt gcgctactac ggcggcatat tgcttggcac cggtgggtta gtgaaagcgt
    49681 atggcggcgg cgtgaatcag gcgctgcgcc agctaacgac ccaacgcaag acaccgttaa
    49741 ccgaatatac tttgcaatgt gaatatagtc agttaaccgg cattgaagcg ttgctggggc
    49801 agtgtgacgg caaaattatc aacagtgatt atcaggcatt cgttctgctg cgggtggcgc
    49861 ttccggcggc gaaagtggct gaattttccg caaagctggc ggattttagc cgtggttcat
    49921 tgcaattgtt agcgattgaa gaataatccc cacttcgttt tgcagaacta aggaagcggc
    49981 agagatgcat tttcgcgcca ttacccgaat cgttggacta ctggttatct tattttcagg
    50041 gaccatgatt atccctgggc tggtagcact catctaccgg gatggagcgg gccgcgcttt
    50101 tacccagacc ttttttgtcg ccctcgccat tggctctatg ctttggtggc cgaaccgcaa
    50161 agagaagggt gaactgaaat cccgtgaggg gtttctgata gtggtgctgt tctggaccgt
    50221 gctgggtagc gtcggtgcgc tcccttttat cttctcggaa agcccgaacc tcacgattac
    50281 cgatgcgttt tttgaatctt tctctggcct gaccaccacg ggggccacta cgctggtggg
    50341 gctggattcg ctccctcacg ccatcctctt ttatcgccag atgctgcaat ggtttggcgg
    50401 gatggggatc atcgtgttgg cggttgcgat actgcctatc ctcggcgtgg gtgggatgca
    50461 gctctatcgc gcagaaatgc ccggcccgct gaaagataac aaaatgcgcc cgcgaattgc
    50521 ggaaacggcg aaaaccctgt ggttgattta tgtcttgctg accgtcgcct gtgcgctggc
    50581 gttgtggttt gctggaatgg atgcctttga tgccatcggc catagctttg cgactatcgc
    50641 tattggcggc ttctcgacac atgatgccag tatcggttat ttcgacagcc cgactattaa
    50701 cactatcatt gctatcttcc tgctgatctc tggctgtaac tacggtctgc acttttcact
    50761 gttaagtggg cgtagtctga aggtttattg gcgcgatccg gaatttcgca tgtttatcgg
    50821 cgtacagttt tcactggtgg ttatttgtac actcgtactg tggtttcata atgtctacag
    50881 ttcggcgctg atgacaatta accaggcgtt tttccaggtg gtgtcgatgg cgacaaccgc
    50941 cgggtttaca actgacagca ttgcccgctg gccgctcttt ttgccggtac tgcttttatg
    51001 ttcagctttt atcggcggtt gcgccgggtc aacgggcggt ggcctgaaag tgatccgcat
    51061 cctgttgctg tttaagcagg ggaaccgtga gctgaaacga ctggtgcatc cgaacgccgt
    51121 ctatagcatt aagctgggga atcgcgcact gccggaacgt atcctcgaag ccgtttgggg
    51181 atttttctcc gcctatgcat tggtgtttat tgtcagtatg ctggcgatta tcgccacggg
    51241 cgtggatgac ttttctgcct ttgcctcggt tgttgcaaca ttgaataacc tggggccagg
    51301 gcttggcgtg gttgctgata actttaccag tatgaacccg gtggctaaat ggatcctgat
    51361 tgccaacatg ctgtttggtc gtctcgaggt ctttacattg ctggtgctct ttaccccgac
    51421 tttctggcgt gaatgatgga gtaatacgtg aaaacattaa ttcttttctc aacaagggac
    51481 ggacaaacgc gcgagattgc ctcctacctg gcttcggaac tgaaagaact ggggatccag
    51541 gcggatgtcg ccaatgtgca ccgcattgaa gaaccacaat gggaaaacta tgaccgtgtg
    51601 gttattggtg cttctattcg ctatggtcac taccactctg cgttccagga atttgtcaaa
    51661 aagcatgcga cgcgactgaa ttcgatgccg agcgcctttt attccgtaaa tctggtggcg
    51721 cgtaaaccgg agaagcgtac tccacagacc aacagctacg cgcggaagtt tctgatgaac
    51781 tcgcaatggc gtcccgatcg ctgtgccgtc attgccgggg cgctgcgtta cccacgttat
    51841 cgctggtacg accgttttat gatcaagctg attatgaaga tgtcaggcgg tgaaacggat
    51901 acgcgcaaag aagttgtcta taccgattgg gagcaggtgg cgaatttcgc ccgagaaatc
    51961 gcccatttaa ccgacaaacc gacgctgaaa taagcataaa gaa
//
LOCUS       DAPOXO010000028        51153 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPOXO010000028 DAPOXO010000000
VERSION     DAPOXO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 51153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51153
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.028"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            212..577
                     /locus_tag="ROH59_001985"
     CDS             212..577
                     /locus_tag="ROH59_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDX4804468.1"
                     /translation="MEKCDFYHIIVLSLNFPGYLKMEYGSTKMEERLSRSPGGKLALW
                     AFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGAL
                     LGGIAWYTRPRPARCRRYE"
     gene            617..1312
                     /locus_tag="ROH59_001986"
     CDS             617..1312
                     /locus_tag="ROH59_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDX4804469.1"
                     /translation="MELQHWQAQFDNWLKNHHQHQDAAHDLCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVTLAKNHPQRQRSSILAAEETRRLLREEFAQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGLALFDGEDPFAQ
                     HRPLDDKRYALDHFQTKLLKLPQTMQTARGKQLAQHNAQFLVEFMAKLGAELAGENEG
                     IDHKVIDAFSPAG"
     gene            1379..2797
                     /gene="dcm"
                     /locus_tag="ROH59_001987"
     CDS             1379..2797
                     /gene="dcm"
                     /locus_tag="ROH59_001987"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-cytosine methyltransferase"
                     /protein_id="HDX4804470.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENH
                     WSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPEHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFNEDIRDITLSHQEGVSDEAAAEH
                     IRQHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRP
                     AMFVLENVKNLKSHDKGKTFRIIMQTLDELGYDVADAADNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMATGEKDFDDP
                     LNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            2778..3248
                     /gene="vsr"
                     /locus_tag="ROH59_001988"
     CDS             2778..3248
                     /gene="vsr"
                     /locus_tag="ROH59_001988"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VSPR family DNA mismatch endonuclease"
                     /protein_id="HDX4804471.1"
                     /translation="MVDVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDAALTERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(3237..4157)
                     /gene="yedA"
                     /locus_tag="ROH59_001989"
     CDS             complement(3237..4157)
                     /gene="yedA"
                     /locus_tag="ROH59_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HDX4804472.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLLAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVI
                     VFAVVLVTLGKYLFPAKPVVAPVIQDASSE"
     gene            4330..5247
                     /locus_tag="ROH59_001990"
     CDS             4330..5247
                     /locus_tag="ROH59_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HDX4804473.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKMRGQAH"
     gene            5326..5508
                     /locus_tag="ROH59_001991"
     CDS             5326..5508
                     /locus_tag="ROH59_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HDX4804474.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRSAEEV"
     gene            5679..7373
                     /gene="yedQ"
                     /locus_tag="ROH59_001992"
     CDS             5679..7373
                     /gene="yedQ"
                     /locus_tag="ROH59_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
                     /protein_id="HDX4804475.1"
                     /translation="MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWRE
                     VVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAV
                     TEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
                     LRLAHNSSSMVEQAVYVSRAGFYVSTLPTLFTRNVPTRYYGYVTQPWFIGHSQRENRH
                     RAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLKNAIDKNLD
                     GEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWERL
                     DHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQS
                     SLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQ
                     AGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGANLTQAAEVAERIRLKLNEKE
                     MLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFASDNA"
     gene            complement(7370..8185)
                     /locus_tag="ROH59_001993"
     CDS             complement(7370..8185)
                     /locus_tag="ROH59_001993"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HDX4804476.1"
                     /translation="MFSIQQPLLVFSDLDSTLLDSHSYDWQPAAPWLSRLHEANIPVI
                     LCSSKTSAEMLYLQKMLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEICQ
                     VLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQ
                     FIARLNELGLQFMQGARFWHVLDASAGKDQAANWITATYQQLSGRRPTTLGLGDGPND
                     APLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR"
     gene            complement(8481..8708)
                     /gene="yodD"
                     /locus_tag="ROH59_001994"
     CDS             complement(8481..8708)
                     /gene="yodD"
                     /locus_tag="ROH59_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HDX4804477.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            8871..9059
                     /gene="dsrB"
                     /locus_tag="ROH59_001995"
     CDS             8871..9059
                     /gene="dsrB"
                     /locus_tag="ROH59_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HDX4804478.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNEAGHQDGIFVEKAE"
     gene            complement(9103..9726)
                     /gene="rcsA"
                     /locus_tag="ROH59_001996"
     CDS             complement(9103..9726)
                     /gene="rcsA"
                     /locus_tag="ROH59_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HDX4804479.1"
                     /translation="MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACD
                     SQRPSVVFINEDCFIHDASNSQRIKHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLL
                     ISSKSIKPESLDDILGDILKKDTTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
                     QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR"
     gene            complement(10016..10801)
                     /gene="fliR"
                     /locus_tag="ROH59_001997"
     CDS             complement(10016..10801)
                     /gene="fliR"
                     /locus_tag="ROH59_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HDX4804480.1"
                     /translation="MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKL
                     GLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEII
                     GLQMGLSFATFVDPGSHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
                     SEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADIISELPLI"
     gene            complement(10810..11079)
                     /gene="fliQ"
                     /locus_tag="ROH59_001998"
     CDS             complement(10810..11079)
                     /gene="fliQ"
                     /locus_tag="ROH59_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDX4804481.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQI
                     NEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG"
     gene            complement(11089..11826)
                     /gene="fliP"
                     /locus_tag="ROH59_001999"
     CDS             complement(11089..11826)
                     /gene="fliP"
                     /locus_tag="ROH59_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310714.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDX4804482.1"
                     /translation="MRRLFSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQT
                     LVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            complement(11826..12191)
                     /gene="fliO"
                     /locus_tag="ROH59_002000"
     CDS             complement(11826..12191)
                     /gene="fliO"
                     /locus_tag="ROH59_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HDX4804483.1"
                     /translation="MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGF
                     APKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEI
                     PQTDFQSVMKNLLKRGGRS"
     gene            complement(12194..12607)
                     /gene="fliN"
                     /locus_tag="ROH59_002001"
     CDS             complement(12194..12607)
                     /gene="fliN"
                     /locus_tag="ROH59_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HDX4804484.1"
                     /translation="MSDMNNPADDNNGAMDDMWAEALSEQKSTSGKSAADAMFQQFGG
                     GDVSGTLQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            complement(12604..13608)
                     /gene="fliM"
                     /locus_tag="ROH59_002002"
     CDS             complement(12604..13608)
                     /gene="fliM"
                     /locus_tag="ROH59_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HDX4804485.1"
                     /translation="MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQR
                     RVVRERLQALEIINERFARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRNEDQNWRDNLVRQVQHSQLELVANFADISLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK
                     "
     gene            complement(13613..14077)
                     /gene="fliL"
                     /locus_tag="ROH59_002003"
     CDS             complement(13613..14077)
                     /gene="fliL"
                     /locus_tag="ROH59_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HDX4804486.1"
                     /translation="MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADD
                     KAQQRVVPSPVFYALDTFTVNLGDADRVLYIGITLRLKDEATRSRLSEYLPEVRSRLL
                     LLFSRQDAAVLATEEGKKNLIAEIKTTLSTPLVAGQPKQDVTDVLYTAFILR"
     gene            complement(14182..15309)
                     /gene="fliK"
                     /locus_tag="ROH59_002004"
     CDS             complement(14182..15309)
                     /gene="fliK"
                     /locus_tag="ROH59_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HDX4804487.1"
                     /translation="MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTD
                     KAAPQLLVATDKPTTKGEPLISDIVSDAQQADLLIPVDETLPVINDEQSTSTPLTTAQ
                     TMTLAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPAEKP
                     TLFTKLTSAQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPH
                     QTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK
                     VDDNQAQIQMISPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ
                     QQQSQRTANHEPLTGEDDDTLPVPVSLQGRVTGNSGVDIFA"
     gene            complement(15306..15749)
                     /gene="fliJ"
                     /locus_tag="ROH59_002005"
     CDS             complement(15306..15749)
                     /gene="fliJ"
                     /locus_tag="ROH59_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HDX4804488.1"
                     /translation="MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWR
                     EKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE"
     gene            complement(15768..17141)
                     /gene="fliI"
                     /locus_tag="ROH59_002006"
     CDS             complement(15768..17141)
                     /gene="fliI"
                     /locus_tag="ROH59_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HDX4804489.1"
                     /translation="MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCVIERQNGSKTHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAE
                     GLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
                     TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFK
                     QLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLE
                     RIFPTVS"
     gene            complement(17141..17827)
                     /gene="fliH"
                     /locus_tag="ROH59_002007"
     CDS             complement(17141..17827)
                     /gene="fliH"
                     /locus_tag="ROH59_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707825.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDX4804490.1"
                     /translation="MSDNLPWKTWTPDDLAPPPAEFVPMVESEETIIEEAEPSLEQQL
                     AQLQMQAHEQGYQAGIAEGRQQGHEQGYQEGLAQGLEQGLAEAKAQQAPIHARMQQLV
                     SEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGK
                     PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQE
                     LCRLAAPGVV"
     gene            complement(17820..18815)
                     /gene="fliG"
                     /locus_tag="ROH59_002008"
     CDS             complement(17820..18815)
                     /gene="fliG"
                     /locus_tag="ROH59_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDX4804491.1"
                     /translation="MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANV
                     TQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRD
                     TASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            complement(18808..20466)
                     /gene="fliF"
                     /locus_tag="ROH59_002009"
     CDS             complement(18808..20466)
                     /gene="fliF"
                     /locus_tag="ROH59_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDX4804492.1"
                     /translation="MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAK
                     APDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGL
                     PKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPS
                     LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLT
                     QSNTSGRDLNDAQLKYASDVEGRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTE
                     EQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNN
                     RQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGK
                     PLPLSNEQMKQIEALTREAMGFSEKRGDSLNVVNSPFNSSDESGGALPFWQQQVFIDQ
                     LLAAGRWLLVLLVAWLLWRKAVRPQLTRRAEAVKTVQQQALAREEMEDAVEVRLSKDE
                     QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE"
     gene            20681..20995
                     /gene="fliE"
                     /locus_tag="ROH59_002010"
     CDS             20681..20995
                     /gene="fliE"
                     /locus_tag="ROH59_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDX4804493.1"
                     /translation="MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDR
                     ISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            21339..21671
                     /gene="emrE"
                     /locus_tag="ROH59_002011"
     CDS             21339..21671
                     /gene="emrE"
                     /locus_tag="ROH59_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family multidrug efflux protein EmrE"
                     /protein_id="HDX4804494.1"
                     /translation="MNPYIYLGGAILAEVIGTTLMKFSEGFTRLWPSVGTIICYCASF
                     WLLAQTLAYIPTGIAYAIWSGVGIVLISLLSWGFFGQRLDLPAIIGMMLICAGVLVIN
                     LLSRSAPH"
     gene            21840..22391
                     /gene="ybcL"
                     /locus_tag="ROH59_002012"
     CDS             21840..22391
                     /gene="ybcL"
                     /locus_tag="ROH59_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Raf kinase inhibitor-like protein YbcL"
                     /protein_id="HDX4804495.1"
                     /translation="MKKLIVSSVLAFITFSAQAAAFQVTSNEIKTGEQLTTSHVFSGF
                     GCEGGNTSPSLTWSGAPEGTKSFAVTVYDPDAPTGSGWWHWTVANIPATVTYLPADAG
                     RRDGTKLPTGAVQGRNDFGYAGFGGACPPKGDKPHHYQFKVWALKTDKIPVDSNSSGA
                     LVGYMLNANKIATAEITPVYEIK"
     gene            22401..23198
                     /locus_tag="ROH59_002013"
     CDS             22401..23198
                     /locus_tag="ROH59_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4804496.1"
                     /translation="MLAKDKTNLKIEEIRMHKHHEIHRVKPLMPALCRIRQGKKVINW
                     ETHSLTVDNNQIILFPCGYEFYIANYPEAGLYLAEMLCYPIDLIEKFQKFYAITDQIR
                     NTTGFCLPQNPELIYCWEQLKTSISRGFSTQIQEHLAMGVLLSLGAHHVNCLLLSDSK
                     QSLISRCYNLMLSEPGTKWTANKVARYLYISVSTLHRRLASEGVSFQSILDDVRLNNA
                     LSAIQTTVKPISEIARENGYKCPSRFTERFHNRFKITPRELRKASRE"
     gene            complement(23355..23879)
                     /gene="tnpA"
                     /locus_tag="ROH59_002014"
     CDS             complement(23355..23879)
                     /gene="tnpA"
                     /locus_tag="ROH59_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDX4804497.1"
                     /translation="MKKETDIRRGRHCVFLKHVHLVFVTKYRRQIFDHDATEKLRTYF
                     SNVCADFEAERVEMDGGPDHVHLLINYPPKLAISSLVNSLKGVSSRLLRRDRPDIAVR
                     YYDKGVLWSPGYFVSSCILTYQLDLITTISVPNRISNVISIPLIIPSTSCNFPTLELH
                     IVQTPDAKKSHVHF"
     gene            23902..25110
                     /locus_tag="ROH59_002015"
     CDS             23902..25110
                     /locus_tag="ROH59_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX4804498.1"
                     /translation="MKRLQAFKFRLRPGGQQERGMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDLERAYKNFFQKRAAFPR
                     FKKRGQNDAFRYPQGVKLDQENSRIFLPKLGWMRYRNSRQVTGVVKNVTVSQSCGKWY
                     ISIQTESEVSTPVHPSASMVGLDAGVAKLATLSDGTVFEPVNSFQKNQKTLARLQRQL
                     SRKVKFSNNWQKQKRKIQRLHSCIANIRRDYLHKVTTTVSKNHAMIVIEDLKVSNMSK
                     SAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLEHKQLWSGGQVLAVPPAYTSQRC
                     ACCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQSGRPLKQ
                     EPTEMIQATA"
     gene            complement(25233..26111)
                     /gene="hslO"
                     /locus_tag="ROH59_002016"
     CDS             complement(25233..26111)
                     /gene="hslO"
                     /locus_tag="ROH59_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDX4804499.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(26136..26537)
                     /gene="hslR"
                     /locus_tag="ROH59_002017"
     CDS             complement(26136..26537)
                     /gene="hslR"
                     /locus_tag="ROH59_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HDX4804500.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAVLLYEETAESVEKREKMALAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            complement(26548..27216)
                     /gene="yrfG"
                     /locus_tag="ROH59_002018"
     CDS             complement(26548..27216)
                     /gene="yrfG"
                     /locus_tag="ROH59_002018"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HDX4804501.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            complement(27281..29416)
                     /gene="igaA"
                     /locus_tag="ROH59_002019"
     CDS             complement(27281..29416)
                     /gene="igaA"
                     /locus_tag="ROH59_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HDX4804502.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTSEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQEIR
                     GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMLFF
                     CLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMKIQAYYESCLNPQLITPSESLIE"
     gene            29736..30296
                     /gene="nudE"
                     /locus_tag="ROH59_002020"
     CDS             29736..30296
                     /gene="nudE"
                     /locus_tag="ROH59_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HDX4804503.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVFEAANRELKEEVGF
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     APDFNEARNVSALFLVREWLKGQGRV"
     gene            complement(30462..33014)
                     /gene="mrcA"
                     /locus_tag="ROH59_002021"
     CDS             complement(30462..33014)
                     /gene="mrcA"
                     /locus_tag="ROH59_002021"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HDX4804504.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVVLSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVDDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRHDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            33134..33913
                     /gene="hofM"
                     /locus_tag="ROH59_002022"
     CDS             33134..33913
                     /gene="hofM"
                     /locus_tag="ROH59_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HDX4804505.1"
                     /translation="MAFKNWQIGLHLQQQEAVAVAIVRSAKECLLHRWWRLPLENDII
                     KDGRIVDVQRLANTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQMAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQRFLPFLPSHQQCLAWRDNEQWLWATRYSWGRKLAVGMTSAKELAAALSVDPES
                     VALCGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKVY"
     gene            33913..34452
                     /gene="hofN"
                     /locus_tag="ROH59_002023"
     CDS             33913..34452
                     /gene="hofN"
                     /locus_tag="ROH59_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofN"
                     /protein_id="HDX4804506.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTS
                     NAEARVNAVLLQAEQQLTRSLQITKPRLLERQQLREQRLQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
                     GRWQFEYQLTRKVSDEHVL"
     gene            34436..34876
                     /gene="hofO"
                     /locus_tag="ROH59_002024"
     CDS             34436..34876
                     /gene="hofO"
                     /locus_tag="ROH59_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HDX4804507.1"
                     /translation="MNMFFDWWFATSLRLRQLCWAVWLLVLVTLIFLSSTHQEERDAL
                     IRLRASHHQQWAALYRLVDATPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            34866..35270
                     /gene="hofP"
                     /locus_tag="ROH59_002025"
     CDS             34866..35270
                     /gene="hofP"
                     /locus_tag="ROH59_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HDX4804508.1"
                     /translation="MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDALTLGTGTNCEPPHWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDADGG"
     gene            35182..36420
                     /gene="hofQ"
                     /locus_tag="ROH59_002026"
     CDS             35182..36420
                     /gene="hofQ"
                     /locus_tag="ROH59_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HDX4804509.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSVAWQNDNIA
                     RQEAEQTRAQANLPLENRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSTLEQWVSQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQQAGGVGQVTT
                     LGSDLSVATATTHIGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            36821..37342
                     /gene="aroK"
                     /locus_tag="ROH59_002027"
     CDS             36821..37342
                     /gene="aroK"
                     /locus_tag="ROH59_002027"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HDX4804510.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            37399..38487
                     /gene="aroB"
                     /locus_tag="ROH59_002028"
     CDS             37399..38487
                     /gene="aroB"
                     /locus_tag="ROH59_002028"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDX4804511.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHSIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGRFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            38579..39865
                     /gene="damX"
                     /locus_tag="ROH59_002029"
     CDS             38579..39865
                     /gene="damX"
                     /locus_tag="ROH59_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HDX4804512.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKARNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTSSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVSLPPISSTPTQGQTPAATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRDTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGGKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            39972..40808
                     /gene="dam"
                     /locus_tag="ROH59_002030"
     CDS             39972..40808
                     /gene="dam"
                     /locus_tag="ROH59_002030"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDX4804513.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVD
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            40826..41503
                     /gene="rpe"
                     /locus_tag="ROH59_002031"
     CDS             40826..41503
                     /gene="rpe"
                     /locus_tag="ROH59_002031"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDX4804514.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            41496..42254
                     /gene="gph"
                     /locus_tag="ROH59_002032"
     CDS             41496..42254
                     /gene="gph"
                     /locus_tag="ROH59_002032"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HDX4804515.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADILMERALTWARQERATLRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            42247..43251
                     /gene="trpS"
                     /locus_tag="ROH59_002033"
     CDS             42247..43251
                     /gene="trpS"
                     /locus_tag="ROH59_002033"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDX4804516.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP
                     "
     gene            43413..44318
                     /locus_tag="ROH59_002034"
     CDS             43413..44318
                     /locus_tag="ROH59_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804517.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELATECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLTHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGLCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGDSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRVDDYPMQQLL
                     RAVVDKHALLAHQQRVVSGEQEPSY"
     gene            44335..44697
                     /locus_tag="ROH59_002035"
     CDS             44335..44697
                     /locus_tag="ROH59_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDX4804518.1"
                     /translation="METRLNLLCDAGVIDKDICKGMMQVVNVLETECHLPVRSEQGTM
                     AMTHMASALMRSRRGEEIEPLDDELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            44781..45944
                     /locus_tag="ROH59_002036"
     CDS             44781..45944
                     /locus_tag="ROH59_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HDX4804519.1"
                     /translation="MFVEALKRQNPALISAALSLWQQGKIAPDSWVIDVDQVLENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVSDAVEQGTDVITVFTLDKAREISAAAVKAGRVQSVLLKVYSDDDFLY
                     PGQESGFVQHSLHEVVAEIQNLPGLHLAGLTHFPCLLWDEAAGKVLPTPNLHTLVQAR
                     DQLAKSGIAIEQLNAPSATSCTSLPLLVEYGVTHTEPGHALTGTIPANQRGDQPERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQRITETYLNAVDDSSIDYTL
                     PLAGEHPVSSAVVLCFRTQIFITRSDVVLVSGIHHGEPEIVGRYDSLGNPLEA"
     gene            45945..47171
                     /locus_tag="ROH59_002037"
     CDS             45945..47171
                     /locus_tag="ROH59_002037"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDX4804520.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLETLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFRDVIDRVEQALVSAGWQVERRGDDLQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     ISFDDAIKMGRIVREQVQVGRVITFGGLLTDSQCILDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVSNPYGVSWQNLVDSQRIMD
                     ITLNEFNTYPTAFICTNIQETDLAGHAEDVARYAERLQVVDRNLARLVEAMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGLVATQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSFRFAGDTL"
     gene            47168..48046
                     /locus_tag="ROH59_002038"
     CDS             47168..48046
                     /locus_tag="ROH59_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HDX4804521.1"
                     /translation="MSFDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     ARGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVGCTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTDLKAGIIAEIGSSEGKITSLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDFLLTTFIPQLRQSGFSQ
                     ADVDVMLRENPSQFFQ"
     gene            48057..48410
                     /locus_tag="ROH59_002039"
     CDS             48057..48410
                     /locus_tag="ROH59_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HDX4804522.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGCFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            48422..49726
                     /locus_tag="ROH59_002040"
     CDS             48422..49726
                     /locus_tag="ROH59_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfT family protein"
                     /protein_id="HDX4804523.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGILILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLI
                     AAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGMSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            49738..50823
                     /locus_tag="ROH59_002041"
     CDS             49738..50823
                     /locus_tag="ROH59_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDX4804524.1"
                     /translation="MKTFPLQSLTLIEAQQKQFALVDTICRHFPGSEFLTCGDLGLTP
                     GLNQPRITQRVEQVLADAFHAQAAALVQGAGTGAIRAALAALLKSGQRLLVHDAPVYP
                     TTRVIIEQMGLTLITADFNDLSALKQVVDEQQPDAALVQHTRQQPQDRYVLADVLATL
                     RAAGVPALTDDNYAVMKVARIGCECGANVSTFSCFKLFGPEGVGAVVGDADVISRIRA
                     TLYSGGSQIQGAQALEVLRGLVLAPVMHAVQAGVSERLLALLNGGAVAEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKLGALPYPVGAESKYEIPPLFYRLSGTFRQANPQLE
                     HCAIRINPNRGGEETILRILRESIASI"
     gene            complement(50931..51098)
                     /locus_tag="ROH59_002042"
     CDS             complement(50931..51098)
                     /locus_tag="ROH59_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HDX4804525.1"
                     /translation="MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISIS
                     KIIGGCGPTAQ"
BASE COUNT        12246 a        12769 c        13713 g        12425 t
ORIGIN      
        1 cgataaaagg ctaataacgg aggcatgatg acacagaaaa ataaaaaggt ataattgtaa
       61 tcagtaccaa tatattgatt gaatgaatta ataaagccga aatcaaagat aaataacatc
      121 gttcaaatcg atttttcctg tattcaccgc cgttgcgcaa aatttatcta tttgttcaaa
      181 aaatgattga gtcttgactg gctcatccaa tgtggaaaaa tgtgactttt atcacataat
      241 agttctaagt ctgaattttc cgggttatct caaaatggaa tacggttcga caaagatgga
      301 agagagactc tctcgcagcc ctggcggcaa attggctttg tgggctttct atacatggtg
      361 tggctatttc gtctgggcaa tggcgcgata catctgggtg atgagccgga tccccgatgc
      421 ccccgtgtcg ggatttgaaa gtgatttagg atctaccgcg gggaagtggt taggagcatt
      481 ggtcggattt ctgtttatgg ccctggttgg tgccttgtta ggcggcattg catggtacac
      541 ccgacctcgt cccgcacgtt gcagacgcta tgaataaaaa ctgctaaggt tgcgactctt
      601 tggcaacgga gcgcgtatgg agttacaaca ctggcaggca cagttcgata actggttgaa
      661 aaaccatcat caacatcagg acgcggcgca tgacttgtgt cattttcgcc gtgtctgggc
      721 tacggcacag aaactggcgg cagatgacga tgtcgatatg ctggtgattt taaccgcctg
      781 ttattttcac gatatcgtga ccctggcgaa aaatcatccg caacggcagc gttcttcaat
      841 cctggcggca gaagagacgc gtcgcctgct ccgtgaagag ttcgcgcaat ttccggcgga
      901 gaaaattgag gccgtttgtc atgccattgc cgctcacagt ttcagcgcgc aaatcgcccc
      961 cttaacaacg gaagctaaaa tcgtccagga tgcggatcgg ctggaagccc tgggggcgat
     1021 tggcctggcg cgcgtatttg ccgtttcagg ggcattgggc ttggcgctgt ttgatggcga
     1081 agatccgttc gcacagcatc gcccgcttga tgataaacgc tacgcgctgg atcatttcca
     1141 gacaaagtta ctgaaattac cgcaaaccat gcaaaccgca agaggcaagc agctggcaca
     1201 gcacaacgcg caatttttag tcgagtttat ggcgaagctc ggtgccgaac tggcggggga
     1261 gaatgaaggt atcgatcaca aggtgataga tgcgttttca cccgctggct gagcgcgtgg
     1321 ccctaaacgg cagtaattat gttaacctgt cggccatctc agatggccgg ttaaatctat
     1381 gcaggaaaat atatcagtaa ccgattcata cagcaccggg aatgccgcac aggcaatgct
     1441 ggagaaactg ctgcaaattt atgatgttaa aacgctggtg gcgcagctta atggtgtggg
     1501 tgagaatcac tggagcgcgg caattttaaa acgtgcgctg gcgaatgact cggcatggca
     1561 ccgtttaagt gagaaagagt ttgcccatct gcaaacgttg ttacccaaac caccggaaca
     1621 tcatccgcat tatgcgtttc gctttatcga tctatttgcc ggaattggcg gcatccgtcg
     1681 cggttttgaa tcgattggcg gacagtgcgt gtttaccagc gaatggaaca aacatgctgt
     1741 acgcacttat aaagccaacc attattgcga cccggcgacg catcatttta atgaagatat
     1801 ccgcgacatc accctcagtc atcaagaagg cgtgagtgat gaggcggcgg cggaacatat
     1861 tcgtcaacac attcctgaac acgatgtttt actggccggt ttcccttgtc agccattttc
     1921 gctggctggc gtatcgaaaa agaactcgct cgggcgggcg cacggttttg cctgcgatac
     1981 ccagggtacg ctgttctttg atgtggtgcg cattatcgac gcgcgtcgtc cggcgatgtt
     2041 tgtgctcgaa aatgtcaaaa acctgaagag tcacgataag ggaaaaacgt tccgcatcat
     2101 catgcagacg ctggacgaac tgggctatga cgttgccgac gcagcagata acgggccgga
     2161 cgatccgaaa atcatcgacg gtaaacattt cctgccgcag caccgtgaac gcatcgtgct
     2221 ggtgggtttt cgtcgcgatc tgaatctgaa agccgatttt actctgcgtg atatcagcga
     2281 atgtttccct gcacagcgag tgacgctggc gcagctgctg gacccgatgg ttgaggcgaa
     2341 atatatcctg acgccggtgc tgtggaagta cctctatcga tatgcgaaaa aacatcaggc
     2401 gcgcggtaac ggcttcggtt atggaatggt ttatccgaac aatccgcaaa gcgtcacccg
     2461 tacgctgtct gctcgttatt acaaggatgg cgcggaaatt ttaatcgacc gcggctggga
     2521 tatggccacg ggtgagaaag actttgacga tccgctgaat cagcaacatc gtccacgtcg
     2581 gttaacacct cgtgaatgcg cgcgcttaat gggttttgaa gcgccgggag aagcgaaatt
     2641 ccgcattccg gtttcggaca ctcaggccta tcgccagttc ggtaactcgg tggtcgtgcc
     2701 ggtctttgcc gcggtggcaa aactgcttga gccaaaaatc aaacaggcgg tggcgttgcg
     2761 tcagcaagag gcacaacatg gtcgacgttc acgataaggc cacccgcagc aaaaatatgc
     2821 gcgcgattgc cacgcgtgat acggcgattg agaagcgcct cgccagtttg ttaaccgggc
     2881 agggccttgc gtttcgcgtt caggacgcca gtctgcccgg acgcccggat tttgtcgttg
     2941 atgaatatcg ctgcgtgata tttacccacg gctgcttctg gcatcatcat cactgctatc
     3001 tgtttaaagt gcctgcgact cgaaccgagt tctggctgga gaagataggt aaaaatgttg
     3061 aacgcgatcg ccgcgatatc agtcgcttgc aggaactcgg ctggcgcgta ctgattgtct
     3121 gggagtgtgc gttacgtggg cgcgagaagc ttacggatgc ggcgcttacc gagcgtctgg
     3181 aagagtggat ctgcggcgaa ggtgccagcg cgcagatcga cacgcagggg attcatttac
     3241 tcgcttgatg catcctgaat aactggcgcg acaacgggtt tggccgggaa gagatatttt
     3301 cccaacgtga ccagtaccac cgcgaagaca attacgccga gcgccagcca ttcaatcttc
     3361 gacagcgttt cgccacccag tcccgtaccc agcaagaccg cgaccaccgg gttaacgtag
     3421 gcgtagctgg tggcgagagc cggactgacg ttgcggatta aatacatata agcgttaatg
     3481 gcgataatcg aaccaaacag cgccagatag ccgaccgcaa ggaagcctga aagggaaggg
     3541 agcgccgtca gtttttcacc cgcaatcatc gacgcaatca ttaacaccac gccagccgcc
     3601 agcatctcaa tcgcacccgc catcatccct acaggtaagg taatgcgcga gccataaacc
     3661 gagccaaacg cccagctaat cgagccgatt aaaatcagaa tcgcgcccca tggattgccg
     3721 cttaagtttc caccgctatt gagcatgatg attccggcaa gcccaatggc gatacccacc
     3781 cattccagtt tgcgcgtttt aatgccaaac aggcggctga agcacagggt aaaaaggggc
     3841 acggttgcaa ccactacggc ggcgatgccg gaaggaacat tttgatgttc ggcaaccgtc
     3901 accatgccat taccgacagc cagcaataac aggccaatca gcgcggcatt gagcagcgga
     3961 cgtagcgggg gaagtttgtg tccgcgcagt agcaaaaatg ccagcaataa aataccggct
     4021 gccaggaatc gaacgcccgc catcattaac ggaggccagc tttccacgcc aatccgaatg
     4081 acaaaatagg ttgagcccca aatgatatac aacgcaaaca gcgcgccaaa aagcggtaac
     4141 aactggcgga aacgcataat ccctcacggc tgaaataaaa aggtggttca tagtaaacgt
     4201 gaaaatcatt ctgctggcga gagatataat tgcacttgat tgttaaataa atgttgacct
     4261 gtgaagcaag tatcagagct gccgtttttg cttcatactt acacccttca acaataaaaa
     4321 tgagagggaa tgcttttggc cgggagtagt ttactgacgt tgctcgatga tatcgccaca
     4381 ctgctggacg atatctccgt gatgggcaaa ctggcggcga agaaaaccgc cggtgtatta
     4441 ggggatgact tatcgctcaa tgcgcaacaa gtttcaggcg tgcgggccaa ccgggaactt
     4501 cccgtggtct ggggcgtggc gaaaggttcg ctgatcaata aagtgattct ggtgccgctg
     4561 gcgctgatca tcagtgcgtt tatcccgtgg gcgattacgc cactgttgat gattggcggc
     4621 gcgtttctct gctttgaagg ggtagagaaa gtgctgcata tgctggaggc gcgtaaacat
     4681 aaagaagatc cggcgcagag tcagcagcgt ctggagaagc tggcggcgca ggatccgctg
     4741 aagtttgaaa aggacaaaat aaaaggggcg attcgtaccg attttatatt gtctgcggaa
     4801 atcgtcgcca tcacgctggg gattgtggca gaagcgccgt tgcttaatca ggtgctggtg
     4861 ctttcaggca tcgcgctggt agtgaccgtg ggcgtctacg gtctggtagg ggttatcgtt
     4921 aagattgatg acctggggta ttggctggcg gaaaaatcca gcgcgctgat gcaggcatta
     4981 ggtaaagggt tattgatcat tgcgccctgg ttgatgaaag cgttatcgat tgtcggcacg
     5041 ctggcgatgt tcctcgtcgg cggcgggatt gtggtacatg gtattgcgcc gttgcatcac
     5101 gccattgaac atttcgccgg gcagcaaagt gcagtggtgg cgatgatatt accgactgtt
     5161 ttaaatctga ttcttggatt tatcatcggc ggcatcgtgg tgctgggagt gaaagccgta
     5221 gcgaaaatgc gcggtcaggc acattaatac tcgcacaggc tattatgcaa aattcgccat
     5281 cttcaactaa ggtgaacaag tttcactcga aaaaaggagg cgagtatgag ctttatggtt
     5341 agtgaggaag ttacggttaa agagggcggc ccgcggatga ttgtcactgg atactccagc
     5401 ggtatggttg agtgtcgttg gtatgacggg tacggggtca agcgggaagc ttttcatgaa
     5461 accgagcttg ttccggggga ggggagtcgt tctgcggaag aagtttgaaa gggtatcatt
     5521 aacaccaggc cggatcacat ccggcctggt gtcccaatgc ctgcaatgaa tgatagtcgc
     5581 gtcttatcat gccaccatta taaaattatc gctgttttgc ggtacgctat cgccgggtta
     5641 tgccagaatc ataaaaaagc aggttgggag tcgtcagggt gcagcacgag acaaaaatgg
     5701 aaaaccagag ctggttgaaa aaactcgcac gccgcctggg gcccggtcat gtcgttaatc
     5761 tctgctttat cgtggtattg cttttttcca ccttgctcac ctggcgtgaa gtggtggtgc
     5821 tggaagatgc ctatatctcc agccagcgta atcatctgga aaacgtagcc aacgcgctcg
     5881 ataagcattt gcagtataac gtcgacaaac tgatcttttt gcgtaatggc atgcgcgaag
     5941 ctctcgtggc gccactggat ttcacctctc tgcgtaatgc cgtaaccgag ttcgaacagc
     6001 atcgcgacga gcacgcctgg caaatcgaac tcaaccgacg gcgcaccctg ccagtcaatg
     6061 gcgtatcgga tgcattagtc agcgagggga atctcctgtc tcgcgaaaat gaaagcctcg
     6121 acaatgaaat taccgctgca ctggaagttg gttacttgct gcgactggcg cacaactcct
     6181 cgtcgatggt tgaacaggcg gtgtatgtct cgcgtgctgg attttacgtt tcgacgctgc
     6241 cgaccttgtt tacgcgcaat gtaccaacgc gttattacgg ctatgtcacc caaccctggt
     6301 ttatcggcca ttcacaacga gaaaatcgtc accgcgcggt acgctggttc acttcgcaac
     6361 cggaacacgc cagcaatact gaaccgcagg ttaccgtcag tgttccggta gacagtaata
     6421 actactggta tggcgtgctg gggatgagta ttcccgtgcg tactatgcag caatttttaa
     6481 aaaacgccat cgataaaaac ctcgatggtg agtatcagct ctatgacagt aagctgagat
     6541 ttttgacctc ttcaaatcct gaccatccaa cagggaatat ttttgatcct cgtgaactgg
     6601 ccttgctggc gcaggcaatg gaacatgaca cgcggggcgg cattcgtatg gacagtcgct
     6661 atgttagctg ggaacgtctg gaccatttcg acggtgtgct ggtgcgcgtc catacgctaa
     6721 gcgaaggcgt gcgcggcgat ttcggcagta tcagcattgc attaaccctg ctgtgggcgc
     6781 tctttaccac catgttactc atctcctggt atgtgattcg ccggatggtc agcaacatgt
     6841 atgttctgca aagctcgttg cagtggcagg cgtggcacga caccttaacg cgtttatata
     6901 accgtggcgc attgttcgaa aaagcccgtc cgctcgctaa attgtgtcag acgcaccaac
     6961 atcctttttc tgtcattcag gtcgatcttg accattttaa agcgattaat gaccgctttg
     7021 gtcatcaggc gggcgaccgt gttctttctc atgctgccgg attaattagc agttccttgc
     7081 gtgcgcagga cgttgccggg cgggtcggtg gtgaggagtt ttgtgtgatt ctgccaggcg
     7141 cgaatctgac gcaggctgcg gaggtcgcag aacgtattcg cctgaagtta aatgaaaaag
     7201 agatgctgat cgccaagagt acaacgatac gcatcagtgc ctcgctgggg gtaagtagca
     7261 gcgaggaaac cggtgattat gattttgaac aactccagtc attggccgac cgtcggcttt
     7321 acctcgcaaa acaggccggg cgtaatcggg tattcgcgag cgataacgct taacgggcgg
     7381 agaaaaaatg gtccagccct tcacgccagc cttccggtcc ttcacgctgc gttcgccaga
     7441 cgcgggccgg atcctcatca tgcagatgga ccccttcacg gtttagccct ttcacaatca
     7501 ccgcgtaatc cattacctcc agtaaaggcg catcgtttgg cccatcgccc aggccaagtg
     7561 tggttgggcg tctgcctgac aattgttgat aggtcgcggt aatccagttg gcagcctgat
     7621 cttttccggc agaggcatcc agtacgtgcc agaagcgcgc accctgcata aactgcaagc
     7681 ccagttcgtt cagacgagcg ataaattgtg ccatacgctc gtcactgtcg cgccagatta
     7741 gcgttaccga cgcctcatgc agctgcgtca gcgccgcctg gctacggctt aatcccgtcc
     7801 attcggcaat ggttgcatcg tcgacatcat caaaagtcgt gaatttaaaa tgttctttct
     7861 cgcgtagcgt atttaaaacc tggcagattt cgccatggct aatacctgag atgatgcgtg
     7921 gaaaaccgtc tatatcctgc cattgttcag caagctggat cactgcgcca ttctctgcaa
     7981 tcagcggtaa gccttgtagc cccaacattt tttgcaagta cagcatttcc gctgaagttt
     8041 tactgctaca gagaatgacg ggaatattgg cttcgtgtaa acggctgagc cagggggctg
     8101 ccggttgcca gtcataacta tgactgtcca gcagggtgct atcaagatcg ctaaaaacca
     8161 gtagtggttg ttgaattgaa aacatgggcg cagtactccc cttaccagga tgattctcaa
     8221 aacagcacaa ataatcaaag atgatttttt cgggagcgat cccgttgaca ccagagccac
     8281 caaggggtga cgcgcgtcac atttctattc ataagtagcg ttaatcattc atagcgcgaa
     8341 tattttcttg tcagcgaaaa aaattgcaga taaggtgatg aacacatcag atttcctggt
     8401 gtaacgaatt ttttaagtgc ttcttgctta agcaagtttc atcccgaccc cctcagggtc
     8461 gggatttttt tattgtgcat tcaacgattc acttcagaga cgctgaagtc atgaatatcc
     8521 agttcgaagg catccgccaa ttcacgccat gtatgatatt cacgtccatc gacgctaacg
     8581 tgttcagaat cgttctggct gcgatgaact tcgctttcgc taatttcatt gatcgccgcc
     8641 agcagggcat cgacatcgac gctgacctca cgttttgcgg tatcgctgta ctcttttgcg
     8701 gttttcatca tctttcctcg caaccgttac tctgttgttg ccgccagtcg ttaagtccgc
     8761 ctggcatctc ttaagtatag accgtcgaga aaatcagcac tcgcgcgcgc ctggcgctgc
     8821 cagaaaaacg aaattgttct acactggcac aaagccacag gaggaaaacg atgaaggtga
     8881 atgatcgggt aacagtcaaa acggatggcg gtccgcgtcg tcctggcgtg gtactggcag
     8941 ttgaggagtt tagtgaaggc acaatgtacc tggtttcgct ggaagactac ccgctcggca
     9001 tctggttctt taatgaagca gggcatcagg acggtatctt tgttgagaaa gcagagtaat
     9061 cttattcagc ctgactggtg ggaaaccacc agtcagaatg tgttagcgca tgttgacaaa
     9121 aataccatta gtcacattat ccgtcagtcg gacgacatgg tagataacct gtttattatg
     9181 cgttttgatc ttacgtttaa tattaccttt atgcgatgaa acggtcttgg ctttgatatt
     9241 catttggtcg gagatttgaa tggttccctg acctgccatc cacattcgca acatactcga
     9301 ttcggttcgg ctcaatgata aagtcggcat atttaaaaac gaggttatcg ttgtatcttt
     9361 tttcagaata tcgccaagga tatcgtcgag agattccggt ttaatcgatt tagagctgat
     9421 caataaattt tttctgacca atagatattc atcaaaatga acattggcaa ttgccataaa
     9481 aacgataaat aacgtattgg gatgttgatt aatgatgtgc ttgatgcgct gactgttaga
     9541 agcatcgtgg atgaaacagt cctcattaat aaacaccact gaagggcgct gtgaatcaca
     9601 agctatggca aggtcatcaa cggtttcaat gtcgttgatt tctctttttt taacccctct
     9661 actcaacaga tacccggtta aacctagtcg ggtgtaacta cataaatcca taataatcgt
     9721 tgacatggca taccctcact caatgcgtaa cgataattcc ccttacctga atatttcatc
     9781 atgactaaac ggaacaacat gggtcaccta atgcgccact ctcgcaattt ttcaggcgga
     9841 cttactatcc cgtaaagtgt tgtataattt gcctggaatt gtcttaaagt aaagtaaatg
     9901 ttgcgatatg tgagtgagct taaaacaaat atttcgctac aggagtatcc tggaagatgt
     9961 tcgcagatat tatttttcgg ataatcctta gggtagcatg ataaacgtta cggaattata
    10021 ttaatggtaa ttcactaata atatcagcca gcaaattaaa aatttcactg aataaatgtt
    10081 cgcaaaaagg cgcaattaac ggcattaatg ccgccattaa agagatgccg acagtcagag
    10141 ttaatggaaa tccaataaca aaaatggata attgcggggc catacgattc agtaaaccta
    10201 atgccagatt cagggtcagc aacagagtaa tgagcggtaa cgccagcatc agcccgttaa
    10261 ggaaaatcaa actccctgct ttggtgagtg ccagaaacgc attgctgttc aacggttcgc
    10321 taccaatcgg cagggtgtga aaggtatcga ccagcagtga aatcaaccat aaatgaccgt
    10381 taaatgtcag gaacagcagt aatgccagca tatccatgat gcgcgctaaa acgggcatat
    10441 tgagatggct gccaggatcg acaaatgtcg caaatgacag ccccatttgc agaccgataa
    10501 tttcgccagc ggttcgcaca gcggcaaagg caaattgcat ggtaaaacca agcgcaatgc
    10561 cgatcaggat ctgctgcacg gccagccaca gagcaaagaa cgaaaaaaca ggaacatcgt
    10621 tggcaggtaa tgatggggca atggcgaacg tgatcatcat tgccagaccc agttttaccc
    10681 gtttcggcac gctgcgttcg ctcagaattg gcgcggtaga aatgagcgcc agcacgcgca
    10741 gtaacggcca gaagtacagg cttaaccagg aaagccattg atcgcttgtt acctgcatca
    10801 ttgtacggcc tacccgatga tatacggcag gttagtgaac aaggtgcgga cgtaatccag
    10861 caacagattg agcatccacg gtccggcaat aataatggcg ataaatacgg cgatgatttt
    10921 tggaataaac gacagcgtca tttcgttgat ctgcgtggcg gcctgcaaaa tactgatgat
    10981 aagacccgtg accagcgcca ccagcaacag tggggcagcc agtgccagcg cgactttcat
    11041 cgcttcagtc cccatcatca tgaccgattc aggtgtcatt ttgcctctct agctgtaaaa
    11101 gctctgcgcc agcgaaccga ccagcaattg ccagccatcc accagtacaa acagcatcag
    11161 tttaaagggc agagcaatgg tggctggggg aaccatcatc atccccaatg ccatcaacac
    11221 gctggcaatc accaggtcga taatcaaaaa agggatgaaa atcgtgaagc ctatctgaaa
    11281 tgcggttttc aactcgctgg tcacgtaggc cgggagcaaa atgcgcatcg gcacagcttc
    11341 aggcccctgc aacgggccgg tattcgccag tctggcaaac aaccctaaat ccgcctcgcg
    11401 ggtctgacgc agcataaact cacgcagcgg ctgcgcccct ttttccagcg cctcctgcat
    11461 tgagattttc tcttcgctga atggctggta cgcatcgaca taaattttgt cgatcactgg
    11521 cgacataata aaaaaggtca aaaacagtgc cagtcccagc aatacctggt taggtggcgc
    11581 ggagggcgtt cccagcgcgt tacgcaataa accaaaaaca ataatgatgc gggtgaaact
    11641 ggtcatcatc agtaaaatcg ctggaatgaa cgtcaacgag gtgatgaaca ccagcgtctg
    11701 caccgggagc gaccagcttt gtccaccgcc aggtagcggc tggctggtga tacccggcag
    11761 ttgcgcgaag gcgaggggcg taatcagcca gagaaggacc ggtgcgacag aaaacaaacg
    11821 acgcatcagg atctcccgcc acgcttaagc aaatttttca tgaccgactg aaaatcggtc
    11881 tgcggtatct cctccgttgg tgctgaaggg ggaagtttat gtagcagatt gatttgccct
    11941 gcggtaacgc cgagcaccag ccgtgcatct tccacatcga ccaccacgac ccgttcacgc
    12001 gcgcccagcg aagcactggc gctaattttc agaccgttaa cgccagtgcg tttaggggca
    12061 aatcccagcc gttttaccag ccaggcggca gcgaggatca gggcaataat ggcgatgagt
    12121 gcgccgctca cctgcagcag tggcgcagca gaaaccggcg cggaagattg cacagtagca
    12181 tggttattca tcactaacgg ctcaggcggc gcatccgctc ggacggggta atgatatcgg
    12241 tgatccgcac gccatattta tcggcaacaa ccaccacttc gccctgggcg attaaataac
    12301 cgttgatcag aatatccagc ggttcgcccg ccagaccgtc cagcgccacg actgatcctt
    12361 gcgtcagacg caacagctct ttgatggtca tccgcgtacg gcccagctcg acggtcagct
    12421 tgaccggaat atccataatc aggtcgatat cctgcaacgt tccgctgaca tctccgccgc
    12481 caaattgctg gaacattgcg tcggcagcgc tttttccgct ggttgatttt tgctcgctca
    12541 acgcttcagc ccacatatcg tccattgcgc cgttgttgtc atcggccgga ttattcatgt
    12601 cactcatttg ggctgttcct cgttcagaga atttaaaatc gggttaatca aatgttctat
    12661 ccgtaacgca tactgaccgt tgagagtgcc gtactgactg gtcagaaccg ggacgccgtc
    12721 aacatgggcg atgatgcgat cgggtttttc tatcggcagg acgtcgccgg gtttcagttt
    12781 taaaatctgc gacaggcgta gcgagatatc ggcaaagttg gccaccagtt ccagctgtga
    12841 atgctgcacc tggcgcacca ggttatcgcg ccagttctga tcttcattac gcgagttttc
    12901 cagcggcggg ttaaccaaca attcccgtag cggctcgatc atgctgaatg gcaggcagat
    12961 attaaattcg ccggtcaggt tgccaatctc cacatggaac ggcgtgttaa ccacaatgtc
    13021 gttcggcgag gtggtgatat tggtaaattt cacctgcatt tccgaacgca cgtactcaac
    13081 ttccagcgga ttaatcgctt tccaggcgtc gctatagcct tcaagcgcca gctttaacat
    13141 gcggttgatg acgcgctgtt cggtatgagt aaactcgcga ccttccactt tggtcgggaa
    13201 gcgtccatcg ccgccaaaca ggttatccac ggcgataaac accaggctcg gcgagaacac
    13261 caccagccct gtgccgcgca gcggtttaag gtggataagg ttcaggttgg tcggcaccgg
    13321 caagttgcgg gcaaattcat ggtacggctg aatgcggatg gccccgacgg taatgtccgg
    13381 gctacggcgc agcaggttga acagccccat acgaaaatgg cgggcaaagc gctcattaat
    13441 gatttccagc gcctgcaaac gttcgcgcac aacccgtcgt tgggtattcg gatcgtacgg
    13501 acgaatgtca ctttcgccgc taacactggc tgtcggttcg tctttgactt cgctgtcacc
    13561 attcaacagc gcatcaattt cagcttgaga aagaatacta tcgcccatgt cgttatcgca
    13621 gaataaaagc ggtatacagc acgtcggtga catcctgttt cggttgcccg gcaacaagcg
    13681 gggtggaaag tgtggtttta atctcggcaa tcaggttttt cttgccttct tctgtcgcca
    13741 gtacggcagc atcctgacgt gaaaacagta acagcaagcg actacggact tccggcaaat
    13801 actcactcag ccgcgagcgg gttgcttcat ctttcagtcg cagggttatg ccgatataaa
    13861 gcacgcgatc cgcatcgccc aaattgaccg taaaggtatc cagcgcatag aagaccgggg
    13921 agggcacgac gcgttgctgc gctttgtcgt cagcggcaac ctgatgcgaa tgccagtagc
    13981 tgtaacctgc gctggcacag gccgcgaggg taatgaatac cagaatcggg atccaaagcg
    14041 atcgcttgct tttcttgctt atcgcgtaat cagtcatgtg ttgcggtctt cctgtgtcgc
    14101 tactgcttat cggctaatta tcctgcgtct tgagcgcaac aaagcgggga aaagacgcgg
    14161 attacggtgc tacctctgac gttaggcgaa aatatcaacg ccgctgttgc ctgttacacg
    14221 cccttgtaaa gagacgggaa ccggaagcgt atcgtcgtct tcccccgtca gaggttcatg
    14281 gtttgctgtg cgttggcttt gctgttgctg ggaagcggcc tgctgctgac cactaaagct
    14341 ttcgccacta atgttgcttt gccctaactg aatgccactt tcggccagct gcgtacgcag
    14401 taccggcagc gctgcttcca gggctgcgcg tacgtgctga tgcggtgaaa tcatctggat
    14461 ctgcgcctgg ttatcatcca ctttgaggga aatttgcact tcacctaaat cctgtgggtg
    14521 cagacgcaac tctgcacttt gttgcccctg gcgggtgaac agcgaaatat gctggcttaa
    14581 tgattgttgc cattcgtgag aacccagcgg tgcactcaaa acaggcgcgg cgacggtggg
    14641 cagtggctgt gtctggtgtg gagtgattag cgggctggcg gcagcagtca ccggcgaagg
    14701 tgtgctgatg acttccgctt tactctgggc ttctgctacc agcggtgtta atggctgagc
    14761 tggtgtgccg ggggcgtcat caggctgtgc tgttgtgagt tgcgcagaag tcagttttgt
    14821 gaaaagcgtt ggtttctctg ccggtaacac ggttgacggt gcatcagtca ctttgggcgt
    14881 attgtcaaaa cccggcaaca tcgcaaaaag ggcgctcagg cttgcggtga cgtcttcatt
    14941 aagatcatcc gctttttcgt cttttgtcgt atttttgtca gccaccgcag ccaacgtcat
    15001 cgtctgagcg gtggttaacg gtgttgatgt ggattgttcg tcgttgatga caggcagtgt
    15061 ttcatccacg gggatcagta aatccgcttg ttgcgcgtcg gaaacaatat cgctgatcag
    15121 cggctcgcct tttgtcgtgg gcttatctgt tgccaccagc aactgggggg ccgctttgtc
    15181 ggtagttgtc tcgcctgcta atgcttcgct caacaacgcg agaaaatctt gtgcagcatc
    15241 gctggctttg ccgccaggca atgtggtggt gtcaacgtcg gcggtaatta agggcgctaa
    15301 gcgaatcatt caggtttcct catggcggcg cgctgggcga actcatccat ctttttctga
    15361 tcgaggcggt tttctgcaag cagtgccgcc gtggattgcc gttcctgcag tgtctgccag
    15421 gcctgcaaac gttgtttctt ttctcgccag ctgttcaggg caatgtcaac tttctgcgtc
    15481 cactgattaa gttgctggcg atgctgagta atggcttttt ccagcgtctg gataaactgc
    15541 tgatagttga tccagcggtt gctggtcatc ccggcactca tatcgctatt gaggttattg
    15601 cgatattcat tctgataatc gatcagcatt ttgagctgtt cttccgcctg ctgacatccg
    15661 cgacgcattt cacccagcag gcgcgcggca tcctctacct ctttttctgc cagatctttc
    15721 agggtcgcca gcgcgccatg ttctgccatc tgccgttatc tcctgggtta tgacactgtc
    15781 gggaaaatac gctccagccc ctggagagac gcttcccagt ccgcgcgttc aaaaatgcct
    15841 tgttgcaaat agccctccag ctgcggccac agggcgatgg ctttgtcgag catcggatcg
    15901 ctgcctttgg catacgcgcc gacgctaacc agatctcggt tacgctgaaa actcgacaac
    15961 agctgtttga aggtgcgcac tcgtgcgtaa tgttgctcac tgatcaacgc cgtcattgcg
    16021 cggctgatcg acgcttcaat atcgatagcc ggatagtgcc cggcttccgc cagtcggcga
    16081 gacagcacaa tgtgaccgtc gaggatggcc cgcgcggagt cggcaatggg gtcctgctgg
    16141 tcatcgccct cggtgagcac ggtataaaac gcggtaatcg agccgccgcc gctaatgcca
    16201 tttccggcac gctcgaccag tgccggtaat ttggcaaaca ccgacggtgg ataaccttta
    16261 gtagcaggtg gttcgccaat cgccagcgca atttcacgct gggccatcgc gtagcgggtg
    16321 agggagtcca taatcagcaa cacatgctga ccacgatcgc gaaaatcttc ggcaatgcgc
    16381 gtggcatagg cggcaccttg cattcgcagg agcggagaaa catccgccgg agcggcaatc
    16441 accactgagc gtgcacgtcc ttcggcaccg aggatattct caataaaatc ttttacttcg
    16501 cgcccacgtt caccaatcaa acccacgaca atgacatcgg cgcgggtgta acgtgccatc
    16561 atccccaaca gcacactttt accaacgccg gacccggcaa acagccccat acgctgcccg
    16621 cgcccgacgg taagcagggc attgattggg cgcacgccgg tgtccagcac atgttcaatc
    16681 ggtgtacgtt gcaatgggtt aaatggcggg gtaatcagcg caccggtttc cgtcgtatcg
    16741 ggggagggga ggccatcgag cggtttaccg ctgccgtcca gaacacgacc taataacgcc
    16801 ggaccgagcg gcaactgctt gccgctttgc agcccttctg ccgaaatgtt tttggcatat
    16861 acacgcgcgc cgggcaggac accttccact tcctccagcg gcattaaaaa cagccgttga
    16921 ccgttaaagc cgacgacttc gctttctact tcgtgcgttt tgctgccgtt ctggcgctca
    16981 atgacacagg ttgcgccgag cggcaattgt aatccggtgg cttccagcac cagcccggta
    17041 gcgcgggtta atcgcccgta gcgacgtacc gcaggcaact gcgccatttt ggcttcaaag
    17101 ttatctagcg tggttagcca gcgagtcagg cgcgtggtca ttacaccact cctggtgctg
    17161 ccagacggca gagttcttgc cagcgagtgg cgacactggc gtcgagatcg ccttcatcgg
    17221 cggagacttt gcaaccgcca ggatggaggg tgggatcgcc ccgcaagcgc cagccatgca
    17281 aacttaaagt tgcgccgagc atatcatcaa cacgttgcag atcatccggg tgtacgcgca
    17341 gctgtggttt accgctgaat aacggttctt gctgcaacaa ctgttggatc tgtttgatca
    17401 gtgccgagtt atccaccgtt ggcgtctgac ctatgacctg acgtgctgcc tccagcgcca
    17461 tctgcatcag gcgcgaagct atcacactat caagcgcatc aagggtagtt tgaaattcgc
    17521 tgaccagttg ctgcatccgg gcatgaattg gcgcttgttg agccttcgcc tctgccagac
    17581 cttgttccag cccctgggcc agtccttcct gatagccctg ttcatgacct tgctggcgac
    17641 cttcggcaat ccctgcctga taaccctgct cgtgggcctg catttgcagt tgcgccagtt
    17701 gctgctcaag gctgggttcg gcctcttcaa taatggtttc ttccgactcg accattggca
    17761 caaactctgc cggtggtggc gcgagatcgt ccggcgtcca ggttttccac ggcagattat
    17821 cagacatagg tatcctcgcc gctgccaatc accatctcgc cagtttcggc aagacggcgc
    17881 acaatcagca gaatcgcttt ctgttcgttt tccacctgcg acagacgcac cggaccacgg
    17941 ttggcgagat cgtcgcgcag aatatcggcg gcacgctgcg acatattgcg caagaatttc
    18001 tcgcgcagtg gctgctcggc ccctttcagc gcgatcagca gcgattcgga atccacttcc
    18061 tgcaacagac gctgaatgct gcgatcatcg acatccacca gattctcgaa caggaacatc
    18121 tcgtcgatga ttttctgcgc cagctcgccg tcgaattcac gcacggcggt aataacggct
    18181 tcttcctgct gcgttttcat caggttgata atttcggctg ccgttctcac gccgcccatt
    18241 ttgctgcgct tgagattctg accgtcgagc aagccattca gtacttcggt cagttccgcc
    18301 agcgcggctg gctgcacgcc gccaaaggtg gcgatacgca acatcacgtc gtggcgcaga
    18361 cgttcatcga acaacgccag aatatcggcg gcctgggcgc gcttcagatg caccagaatg
    18421 gtggcgataa tttgcggatg ctcatcgcga atcagatcgg cggcgctctg cggctccata
    18481 aagttgagcg tttcaatacc gctggcggta tcgcgggttt cgagaatatc ttccagcagg
    18541 ctggcggcac gttcttcacc cagagctttg accaataccg aacgcagata atcgttggcg
    18601 ttgatattca gtgcggcaaa ctgttcagct tcttgctcaa actccgccag cacatcggtt
    18661 agctgcttgt tggagatctg cgtgacgttc gccattgcag cgctaagggt ttgcacttcg
    18721 cgctgggaga ggtgcttgaa cacctctgcc gcccggtctt cgccaatggt catcagcagg
    18781 atgacgcttt tatcggtgcc tgtcaggtta ctcatgatcg ttatttatcc actggcgaat
    18841 gaccagcgcc accacgcgcg gatcgttatc agacatttca cggatacgct ggctcatgac
    18901 ttctgccccc agtcgttggt tagcgcgccg ttgttggagt tgttcgtctt tgctcagacg
    18961 gacttccacc gcatcttcca tttcctcgcg ggccagcgct tgttgctgca cagtcttcac
    19021 cgcctcggcg cgacgtgtta gctgcgggcg taccgctttc cgccacagca accacgccac
    19081 cagcagtacc agcaaccagc gaccggcagc cagcaactga tcgataaaca cttgctgttg
    19141 ccagaacggc agtgctccgc cgctttcgtc actgctattg aacggcgagt taacaacatt
    19201 gagcgaatca ccgcgttttt cagaaaagcc catcgcctcg cgggtcagag cttcaatttg
    19261 cttcatctgt tcgttgctga gaggcaatgg tttaccgtct ggcaaggttt tgtaattcac
    19321 cactaccgcg actgacagac gttgcacatc gcccacgttc attttggtat gacgaatggt
    19381 gcgatcgact tcgtagttac tggtttcatt ccgctgtgtg ctacgcggcc cactattgct
    19441 ggtggtgctc gcctgctgct ggcggttatt ttgatttgcc ggaggcgtgc tgattggtgc
    19501 gttattcgca ggtgccggtt gattcgacaa cgcccccggt acgccgcccg gataaccgga
    19561 accgctttgc tcgctctcat taagctggcg tgaacgaagc gccgcatgag attcatcacc
    19621 gttagggcga tactgttctt ccgtttgttc tttactggcg aagtccagtt gcgccgtgac
    19681 ctgggcgtga atattaccgt taccaacaat aggcgacagg atcgcttcaa tacgccgctg
    19741 aatacggcct tcgacatcgc tggcatattt caactgagcg tcattaagat cgcgcccgct
    19801 ggtattggac tgggttaaca gatgcccgcc ctgatccacc agcgtgacgt ttcctggcgg
    19861 cagaccagca accgcgctgg aaaccagatg tacaatagcg ctaatttgcc cttcatcgag
    19921 tgcgcggccg ggtaacagat ttaccgtcac cgatgcagaa ggggattttt gttcacggac
    19981 gaataaagac ggtttcggca ttgccagatg tacgcgcgcc ccttttaccg ggccgatagt
    20041 ttcgatggta cgagaaagct cgccttccag cgcccgctga taattcacct gttcgctgaa
    20101 ctggctgata ccaaactttt cctgatcgag cagttcgaaa ccgaccgcgc cgcctttggg
    20161 caaaccttgt tgcgccaggc gcaggcgcag ttcgtgaact ttatctgccg gaacctcaat
    20221 agcgccgctg gcttcgctga agcggtaagg aatattcatt tgcgtcagtt ggctgacaat
    20281 tgcgccacca tcctgatcgg aaagattgct gaataatgtg cggtagtcgg gggctttcgc
    20341 ccacaggatc agtgcgacca tgaccgccac tgctgcggaa ccggcaacaa tcaatggaat
    20401 tttcggattc gcacgcaggc gattaagcca ctcaagagat tttgtctggg ctgcagtcgc
    20461 attcatcgcg cacctcgtgg ctgattatgg acggcgttat tggcaaagtg gaacaagact
    20521 cactcccggg tcagcaaact cgaaaaattg acgctcccat tatttgtgct ttcgtttttt
    20581 tctatccgcc aataaacccg tttttttgtt gctatttagc gcctttgtct tattgactta
    20641 ctggtaggct ttgctatcag aaattatccg ggagacgaaa atgtcagcga tacaggggat
    20701 tgaaggggtt atcagccagt tacaggctac ggcgatgagt gcgcgtgcgc aggaatcact
    20761 gccgcaaccg accattagtt ttgccgggca gctgcacgcc gcgctcgatc gcataagcga
    20821 tacacaaaca gccgcccgca cgcaggcaga aaaattcacc ctcggtgaac ccggcgtggc
    20881 gctaaacgat gtgatgaccg atatgcaaaa agcctcagtt tctatgcaaa tggggattca
    20941 ggtgcgtaat aagctggtgg cggcgtatca ggaagtgatg tccatgcagg tgtaggttgt
    21001 gtaacctgtt gactatgctt gtttaattat atccgatccc acagcgtggg gcatggatgg
    21061 gcaaactcac tcaatttctg gtttaaaatg gatacctgat cctggttgtt ttctgccatc
    21121 cacgatccgt aaacgcgata acatgttttg tcttcgcttt gctcccagga agagtgaact
    21181 ctttcgttag cctggggttc cttctgatca ttattgttcc tgcctttatc tcttgccacg
    21241 ccagagcccc ctggatacac atacaccagg atgaaaacag tgagttgtgt tcaaactgta
    21301 gtacaattct ctccagtatg aacaggaaag aatatgctat gaacccttat atttatcttg
    21361 gtggcgcaat acttgcagag gtcattggta caaccttaat gaagttttca gaggggttta
    21421 cacggttatg gccctctgtt ggcacaatta tttgctattg tgcatcattc tggttattag
    21481 ctcagacgct ggcttatata cctacaggga ttgcttatgc tatctggtca ggagtcggta
    21541 tcgttctgat tagtttgctt tcctggggat tttttggtca acgactggac ctgccagcta
    21601 tcataggcat gatgttgatt tgtgccggtg tgttagtcat taacttgttg tcacgaagtg
    21661 caccgcatta aaaaataatt atccttgaga taacaggaat ctgatttgtg catattatgg
    21721 ctaatgttcg gggcaccttt ataattatga ttgcatttgc gcgatcattg cgcctttatg
    21781 cataatgaga tcaaggcaca tcaaataaaa taacgatagg tcacaacaat gaggttttta
    21841 tgaaaaaact tatcgtttca agtgtattgg cattcataac attttctgcg caggccgcag
    21901 catttcaggt cactagtaat gaaataaaaa caggagagca acttacaacg tctcatgtat
    21961 tttctggatt tgggtgtgaa ggtggtaata catcgccctc attaacctgg tctggtgctc
    22021 ctgaaggcac caaaagcttt gccgtaactg tgtatgatcc agatgctcct acaggcagtg
    22081 gatggtggca ctggactgtt gctaatattc cagcaactgt aacatatttg cccgctgatg
    22141 caggaagacg tgatggtaca aaacttccga ctggtgctgt tcaaggccga aatgattttg
    22201 gttatgcagg atttggtgga gcatgtcctc ccaaaggaga taaaccccat cattaccagt
    22261 ttaaagtatg ggctctaaaa actgataaaa ttcctgtgga ttctaattcc agcggagcgt
    22321 tagttggtta tatgcttaat gccaataaaa ttgcaaccgc tgagataaca ccagtttatg
    22381 agataaagta gggtaagagt atgctggcaa aagataagac taacctaaag attgaagaaa
    22441 tacggatgca taaacatcat gagattcaca gggttaagcc tcttatgcca gctttatgtc
    22501 gtatccgtca gggaaaaaaa gttatcaatt gggagacgca tagtctaact gttgataata
    22561 atcagataat attatttccc tgtggatatg aattttatat tgcgaattat ccagaagcag
    22621 gtctttatct tgcagaaatg ctttgttatc ccattgatct aattgaaaag tttcaaaaat
    22681 tttatgcgat aactgatcaa attcgtaaca cgacaggttt ctgcttacct cagaaccccg
    22741 agttaatata ttgttgggag caactaaaaa catctatttc ccgaggcttc tcaacgcaaa
    22801 ttcaggaaca cttagcaatg ggcgttctac tttcattagg agcacatcat gttaattgtt
    22861 tacttttatc agatagtaaa caatcattaa taagtcgttg ttataaccta atgctatccg
    22921 aacctggaac aaaatggaca gcaaacaagg tagcgagata tctctacatt tctgtttcca
    22981 cattgcatcg ccgtctggca agcgagggag taagttttca aagtatattg gacgacgtga
    23041 ggttaaataa tgcgttgtct gctatacaaa cgacagtaaa acccatcagc gagattgcca
    23101 gggaaaatgg ttacaagtgt ccttctcgtt ttactgaaag gttccataat cgttttaaga
    23161 taacaccaag agagctaaga aaagcgtcca gagagtaaaa gtattttatg aaggagcaac
    23221 agcatcgatt tttattttgg aaaataaata cggcatactc aacctattgg agtctgaaca
    23281 atccggtgac ttctgcgcta atcggggacg tttctaagca catataattg atactatctt
    23341 cctccatcac aatttcagaa atgcacgtgt gatttttttg catccggcgt ttggactatg
    23401 tggagctcaa gagtgggaaa gttacaagag gttgagggga taattaaagg gatgcttatg
    23461 acattagata tccggttagg tacggatatc gttgttatta aatctagttg atacgttaag
    23521 atgcagctac tgacaaaata gccaggactc cacaaaacgc ctttgtcgta atacctgact
    23581 gcaatatctg gtcgatctcg tcgcagtaac ctactcgata cgcctttgag gctgtttacc
    23641 agactggata tcgccagttt gggaggatag ttaattaaca aatggacgtg atctggtccg
    23701 ccatccattt caacccgttc agcttcaaaa tcagcacata catttgaaaa gtaagtgcgt
    23761 agtttttctg tcgcgtcatg gtcaaaaatc tgacgtcggt atttagtaac gaagaccagg
    23821 tgaacatgct tcaggaaaac acaatgcctt ccgcgtcgga tatcggtttc ttttttcata
    23881 ggccaaagta tgatttggcc catgaaacga ctacaggcat tcaaattccg gttaagacca
    23941 ggtggtcaac aggagcgtgg aatgaggcgc ttcgcaggcg catgtcgttt cgttttcaat
    24001 cgtgctctgg cgcttcagaa tgagaatcat gaggccggta ataaatacat cccttacggg
    24061 aaaatggctt cctggctggt tgagtggaaa aatgccactg aaacgcaatg gcttaaagat
    24121 tctccctcac agccattgca acagtcactg aaagaccttg agcgggctta caaaaacttc
    24181 ttccagaagc gggctgcttt tccccgattc aaaaagcggg gacagaatga tgcattccgc
    24241 tacccgcagg gcgttaagct cgatcaggaa aacagccgta tttttctgcc gaaacttggt
    24301 tggatgcgct accggaatag ccgtcaggtc acgggagttg tgaaaaatgt cactgtcagc
    24361 cagtcctgcg gtaagtggta catcagtatt cagacagaaa gtgaagtatc aactccggtt
    24421 cacccttcag catcaatggt cgggctggat gctggcgtgg ctaaactcgc cacgctgtca
    24481 gatggcacag tctttgagcc tgtaaacagt tttcagaaaa accagaagac gctggcgaga
    24541 cttcagcgac agttaagccg caaggtcaaa ttcagcaaca actggcagaa gcagaaacgc
    24601 aaaatacagc ggctgcattc ctgtatcgca aatatccgca gggactacct tcacaaagtc
    24661 acaacgaccg tcagcaaaaa ccacgcaatg atagtcattg aggatttgaa ggtcagcaac
    24721 atgtcaaagt cagcagcggg tacggtcagc cagccggggc gcaatgtccg ggcaaaatca
    24781 ggtttaaacc gttcgatact ggatcagggc tggtatgaaa tgcgccgcca gcttgagcac
    24841 aagcagctct ggagtggcgg tcaggtgctt gctgttccgc cagcgtacac aagccagcgt
    24901 tgcgcgtgct gtggtcatac agcgaaagaa aaccgcctgt cacaaagtaa attcagatgc
    24961 caggtatgtg gatatacagc gaacgccgat gtaaatggcg ctcgtaacat tttagcggcg
    25021 gggcacgccg ttcttgcctg tggagagatg gtgcagtcag gccgcccgtt gaagcaggaa
    25081 cccaccgaaa tgattcaggc gacagcctga acgtagcagg gatccacgtc cttcagggcg
    25141 tggaggatgt caattcatag gcctggtaag cgcagcgcat caggccatta cgtcgtaaaa
    25201 tccggcagag tcctctctgc cggacatact cattaatgaa cttgcggatc tgccggagac
    25261 gcgttgttgc ggatctcggc aatatccatc gcattgaaca gatagtggtt accgcagtaa
    25321 tcacaatgca tgtcaatttc gccatcttcc gccaggatgc tatcgacttc ttcatcaggc
    25381 agcgttttca gcgcatcggc gcaacgttca cgcgagcagg tgcatttgaa ctccacatcc
    25441 tgcggatcgt aaaccgtcac ctcttcttcg tgatacaaac gccacaacac ttcgtttgcc
    25501 ggtaaagtca gcagttcttc ggttttgatg gtttcggtta gcgtcgccag gtggtcaaag
    25561 tcgtcctgct gggcattttg cgcaggcatt acctgcaaca acataccgcc tgcagccggt
    25621 ttgccgtcta cgtcgccggt gcgaataaac aggcgcgtcg gcagctgttc agaacgcata
    25681 aagtaatctt ccaggcaggc cgccagggta tcaccttcca gaccaaccac gccctgatag
    25741 cgttcgcctt cgctcggggt gatggtgatc accacgtaac cattgccgac cagcgttttc
    25801 aggtcggcat tttctggaat ttcgccctgc acgcgcgcca caccgcgcat ctgctggttg
    25861 ttgttaccgt taataaccgc cagattcatc ggaccgtcgc cttgcagctg tacggtgata
    25921 tcaccatcaa acttcaacgt agcggttaac aggctggtcg caaccagcag ttctgccagc
    25981 acgtttttaa cgggctgcgg ataatcgtga ttctcaagga tctgttgcag ggtttccgaa
    26041 acggttacca gttcgccgcg aacggcaaag ttttcaaaca gatagcgatg taattggtca
    26101 tgttgcggca taatcatctc tcttgcaggt gacagttatt cactgtcgcc gtgtttaaat
    26161 cgtaacaggt cgcggcgctc ttttttgtcc gggcgtcggt ccggatgcgg catggttaag
    26221 gcattaagtt tacgtgccag cgccattttt tcgcgtttct ctacactttc cgcagtctct
    26281 tcatacagca agactgcctc gctggcgggg cgacgctgtt cagtaatcgc ctttacaatc
    26341 accgtgcgtt cgtcatttcc ctggcgcaga gtgagcgtgg cattcagctc gacgattttg
    26401 ctcggcttgc tgcgctgccc gttgtaatgc accttaccac cttcgatcat ttcgcgggcc
    26461 agcgcgcggg ttttataaaa acgggcggcc catagccatt tatccagtcg aacctcaaca
    26521 gcaggttttt ctttcatggc gtctccttca cattagcgag gggatcaggc ggcggtagtc
    26581 attcagtgac ggatggcgct gatactgttt ctcggcaatc ccggagtcag gattagtcac
    26641 accgaggcag taacgaatac caaattgcgc ggcagcatcg agaatcgctt cgctgtcatc
    26701 aataaacagc gttctttcag ctttaagacc cgtagcttcg gccaccgcat gccataaccg
    26761 ctgatcctct ttcggataac caaatgtgtg ggtggaaagt aataaatcaa ggtgtgcgtc
    26821 cagaccggta tgctcaagtt ttaccgccag gttgtgcgga tgcgcattgg tgagcaaaat
    26881 tcgctgttta ccgctggctt tcagtgcctc aagaaacgga atggtatctt cacgcagtac
    26941 ggcacgcggt cccatctcgg tggtcatcgc acagatatcc agacccagtt gctcactcca
    27001 gtaatcaaga cagtaccagt ttagcgtatg ctgtacgtcg tgatattgct ggcgcatata
    27061 ttccatcgct tcctgtggcg taactccgtt tttcgcgccc catgtttcag gcaccagctt
    27121 ttgccagaaa tagttatcga aggcgaggtc gagcaacgtg ccgtccatat ccagcagaac
    27181 ggtatctacg tcctgccagg caatgttgat atgcatgagg gaaatctcca gagtgaagca
    27241 atttgcgcga cagggtagca taacctgccg cgcaaacgtg ttattcgata aggctttcgg
    27301 aaggggtgat cagttgcggg ttcaggcagc tttcataata ggcctgaatc ttcatcatgc
    27361 gagtacgatg acgctggtaa cgacgccagg cctgtacgcc attataaatg gcgctaccca
    27421 gcatcgtcag tagcagcagc gtggtgctga gatagcgcca cagaccggaa cgatccggga
    27481 tcggatgaag gccaatatgc tgcgtaccat tggcgtcagt gaagattttt gtgacgatac
    27541 cttcggcgtt aaacggcgta tgcatcagca tttgtgccag tttctggaaa gcgttccact
    27601 gttcttgcgg cggatagtcg taaagtgatg ccgaaggcca gggctgatca acaaaatcgc
    27661 tgccttcgtc gctgacaatc aggaacccgc cgggggccgg actgtttagt gattgtgccg
    27721 ctcgcgccgt ttcatgcgtg ataaacggcg cggtagaggt ggccaccagg ttatccagcg
    27781 attccgcact caccgggcgt aataacacat tcacgccatc gagtttcccg gcgttggcgc
    27841 gttttaccag cgcgtcccag tctttactgt tgccgagatt gaccagcgca tttttcagtc
    27901 gcacacagtc atctttggca gaacacagat ccgctgtctt cagtactatg tcgccaaaat
    27961 catcaagcaa taccatgccg gatttttgaa ttgctgaacg taatgaggcg ctgacgcgag
    28021 attcatcttc cggtttaggg tgcagctggc gattaactgc ttcggtcaat gccgtcgctt
    28081 tgttgaccaa ttcagattct ggtaatggca atgagcgggc gtcgttccag atgatctgcg
    28141 agcagtcaaa cggtaaaaaa ggtgagttgg ttttcgcgct ccaggtaccg gaagtgcgaa
    28201 tattacacat tcccgtaccg ctaatacgca atgtatcgcc aacccgcacg ccagcgtcag
    28261 ccagttgttt cacgctggtg gcttcaatgg tctgcgcgcc tttcatccac gagagggtga
    28321 atttcagcgg catatccagc gggatccaga ataacagcat aaacagcacc agtagcgagc
    28381 ccgcagcgat aatcgtactg cgcagccagt gctgtaacgg aaagtttttt acttcatcat
    28441 ggagcgaaag atatcgcccc tgacgcacta cgtggcggtc gagatagata tcgatatcgg
    28501 tttgttggcc gagatcctga gcaatgtagg gctgccagtg tgcgggatag accaggtcga
    28561 taataccgag tgaaatattg ttgatctgtt cctgatcgtt ttcgccaaac aatccccaac
    28621 gacggggtgt accgcgcaga caatgaattt cccgcaggga ggattttgcc gggggcgcga
    28681 atagccccca cagacctgcg cccagcagca gtaacgcgcc gcctgccagc cacggaacaa
    28741 agacatccgg ggtaatcagg cagaaaaaga gcatcaggaa ggaggcgaca atcagcaacg
    28801 cttcgcgcag cccgcgcgga cgactcagcg catattcttc atgcgtttct ttgcgaatat
    28861 tgagcagctc tatttgctcg ctctcttccc cgcgaatcga cgcctgcgtt gacggaacag
    28921 gttgcaaggc atagccgcga atttcctgca tgtactcctg cagcgtatga ccgttgagtg
    28981 aaataaccag cggcagcgaa tcggtatgaa tcagttcaac ggtattctca tcgttgatgt
    29041 actgttccca gaaagggggc aggtggactt ctaccgaatc gaggtagtaa cgccatttat
    29101 tcggatcgtc ggtagagatg ccataacgcg tgatagcgtg tgtcagcatc atgacgttgt
    29161 tgctttcggc attcagcgcc agagagatcg gtgccgcgct ggctcccgtt gggccaggca
    29221 cctgtaatac ctgcgtcagg ctctcaagat aattttcaac ggcgctacgt tcttcagatg
    29281 tgagtttacg cgtttgcgca tccgcgaagg cgttggtcca gggcagctga cgccgtctgg
    29341 atcgcacttt tatcagccat cccgcaagta gtgagcaggc cagcaaagca gctaaaaaaa
    29401 tcacaatggt gctcatgctt tccccatctt acttagtctg tcaggcgtgg tcagtcgcac
    29461 cggacacaat acatgattct gcggttggct atcggcaagc gtggagttta acttgagcat
    29521 cattaagcac atcacagtaa ccgctgatca tagcaaaccc tctgaaggcg gaatatcagc
    29581 aaattcctgg agttatttca acctattgac ttttaatttg atttgaggac gattatttat
    29641 taagttacat aaatgtaaat aacgcgcaat tcacattgcc gaaagcgtgt ccgatatcgc
    29701 acaataaccg ctgatttcac agcatagatc ccacgatgag caaatcatta caaaaaccca
    29761 ccattctgaa tgttgaaact gtagcccgtt cccgactgtt taccgtcgaa agcgtggatc
    29821 tggagttcag caatggcgtg cggcgtgttt atgaacgaat gcgtccaacc aaccgggaag
    29881 cagtgatgat tgtgccgatt gtggacgatc acctgatcct gattcgcgaa tacgcagtgg
    29941 gaactgaatc ctacgaatta ggtttttcga aaggattaat tgatccgggt gaaagcgtct
    30001 ttgaagccgc taaccgcgag ctaaaagaag aggttggatt tggtgcgaac gatctgactt
    30061 ttttgaagaa gctcagcatg gcaccgtctt acttttccag caaaatgaat atcgtggtag
    30121 cgcaagatct ctacccggaa tcactggaag gcgatgagcc agagccgtta ccacaggtgc
    30181 gctggccgct ggcgcatatg atggatttgc tggaagcccc tgacttcaac gaagcgcgta
    30241 atgtcagcgc gctgttcctc gtgcgcgaat ggttgaaagg gcaggggcga gtgtaaatgc
    30301 gtgaagttta cctgatgcat aatgcttatc aggcttacga agttcctgca atttattgaa
    30361 ttttcaattt tttgttggcc ggataacgcg ttcacccgca tccggcataa acaagtgcac
    30421 tttgtcagca aactgaaaaa ggcgccgaag cgccttttta atcagaacaa ttcctgtgcc
    30481 tcgccattat cgataatggt cgttcccacc tcgtgcaccg cctgttgtgt cggctgcgta
    30541 ccttcgatga aatactcttc gcggctgttg ccaccattag ctaattgccc ggtgctgcga
    30601 tcgatattca ccgtcacaat acccggtggc ggcgtcagcg gctgttccgg tacaccttca
    30661 agaacggctt tcatataagc gtcccatgca ggctgggcac tcttggcacc gccttcgtaa
    30721 cctgagatct gatctttaat cgctccggaa gccgttgtat gaccgagatt acgacggtga
    30781 tcatcaaagc caatccagac cgaggtcaca acgcccggac cgtaacccga gaaccacgca
    30841 tctttcgaac tgttagtggt acccgttttt ccgcctatat catgccgttg taaatcacga
    30901 cctgctcgcc agccagtacc ctgccagcct ggttcaccaa aaatattggt gttcaaggca
    30961 ctcttaatca ggaatgccag cggagtgttg atgacgtgcg gtgcgtactc ctgcgcgccg
    31021 gtcttcgcca ctaacgcctg atttgcctgc tccagctgcg gcattggtac agaaacattc
    31081 tgctgctcgc gggagatagc gacatcttca acatcgttat tttccagcac gttcgatttc
    31141 tgcgtatcac cgtaaatcac cggaatatcg cattccgggc aggctacttt cggtttcgct
    31201 tcgaaaatta cgccgccctg atcgttttca attttgctga taaaccacgg gtccaccagg
    31261 aagccgccgt tcgccatgac cgcgtagccg cgcgccacct gcattggggt gaaggaagct
    31321 gaacccagcg ccagcgattc ggtgtggaca atgttttgtg ccgggaagcc gaagcgttgc
    31381 agatattctg cagcgtagtc gacgcccatc gcccgcattg cgcgtaccat caccacgttt
    31441 ttcgactgac ccagcccctg acgtaagcga attggaccgg catattgcgg tggtgagttc
    31501 ttcggctgcc agtcagaacc ggcacctgca tcccagcggg aaattggcac atcgttcaac
    31561 atacttgcca gcgtcagacc tttatccatc gccgcggtgt agaggaacgg tttgatgttg
    31621 gaacccacct gacgcagtgc ctgagtggct cggttaaact tgctctgatt gaaatcaaag
    31681 ccaccgacca gcgccataac ggcaccgttt tgcggattga tcgacaccag cgccgagttc
    31741 acttccggca cttgcgccag ccaccatgca tcgtcaactt gacgaaccca gatttgctga
    31801 cccgtttgca gaacatcggt cactttacgc ggcgtcggtc cctgctgagt atccgaacgg
    31861 taaggacgcg cccagcgaac accttccata ctcaatacga cggtcgaccc gtctgccagc
    31921 atcgccgttg cttcctgagg attggcgctg gtgactgcgg caggcagcag cggaccatag
    31981 gtcggcagcg ccttcagcgt atcggtaatc ttgttgttat cccacgccga ttcgcccact
    32041 ttccacagca catttgccgg gccgcgatag ccgtggcgca tgtcgtagtc cagcacgtta
    32101 ttacgtaccg cctgctgtgc ggcctgctgc actttgcggg tgatggtggt gtaaatgcga
    32161 taaccgtctt cataggcact ttcgccataa cggttataca tctcctggcg caccatttcg
    32221 ctcaggtatg gcgcagagaa agcaatctcc ggcgcgtgat agttagcgtt aatcgcctca
    32281 gtgcgtgtct gatcgaactg ttgttgggtg atataccctt catccagcat ccgcgacagc
    32341 acgacgttac gccgcgcgac ggcacgatcc attgagtaga gcgggttgaa ggtggaaggc
    32401 gctttcggca gcccggctat caccgccatt tcgttcaacg tcagttggtc gacagtttta
    32461 ccgaaataga cttgtgccgc agcaccgaca ccataggcgc ggtaaccgag gtaaatcttg
    32521 ttcagataaa gctcgaggat ctcgtctttc gttagcaact gttcaatgcg aatcgcgagg
    32581 aagacttcct taatcttgcg catcagcgtg cgttctggac tgaggaagaa gtttctcgcc
    32641 agctgctggg taatggtact cgccccttgt gacgcgtgac cggagaacag cgccacgctt
    32701 gccgcacgga agatccccac cgggtcaacg ccgtgatgct cgtagaagcg gctgtcttcc
    32761 gtcgcgataa aggctttcac catctccggc gggatttgat ccaacgtaac cggaatacga
    32821 cgtttctcac cgtattgagc aatcagctcg ccatcggcgc tgtaaatctg catcggaatt
    32881 tgcaggcgaa catcttttaa tgtcgccaca tccggcagtt gtggctcgat gtagcggtat
    32941 aggccataaa tcgagcctgc tcccagcaga atgcaacaga ctgcaaggat caaaaaatac
    33001 tttacgaact tcactggaaa tttcccattt agtttcattt gggcagttta taaacaaacg
    33061 cgcggtagta taaaggcaag ccagacgcat tgatataccc gtcagagtga cgggtgataa
    33121 ggagatcatc acaatggcat ttaagaactg gcaaattggt ttgcatttac aacagcaaga
    33181 agcggtagcg gttgctatcg tgcggagcgc aaaagaatgc ttattgcacc gctggtggcg
    33241 gttgccactg gagaacgaca ttatcaaaga tgggcggatt gttgatgtgc agcggctggc
    33301 taacacgttg ttaccgtgga gtcgcgaact gccgcagcgt catcacatta tgttggcgtt
    33361 tcccgccagt cgcacattac agcggtcatt tccacgcccg tcgatgtccc tcggtgagcg
    33421 ggagcaaatg gcctggctgt ccgggacgat ggcccgtgaa ctggatatgg atccggactc
    33481 cctgcgcttc gattacagcg aagactcact cagtcccgcc tataacgtga ctgccgcgca
    33541 aagcaaagag ctggcaacgc tgcttactct ggcagaaagg ttgcgtgttc atgttagcgc
    33601 gatcactccg gatgccagtg cattacagcg attcctgcct tttttacctt ctcatcagca
    33661 atgtctggcc tggcgtgata acgaacagtg gctgtgggcg acgcgctata gctgggggcg
    33721 caaactggcg gtggggatga ctagcgcgaa ggagctggcg gcagcgttat ctgttgatcc
    33781 cgaaagcgtc gcgctatgtg gcgaaggcgg atttgacccc tgggaggcgg tttctgttcg
    33841 tcagccgccg ctaccgccac caggtggaga ctttgccatc gcgctggggc tggcgcttgg
    33901 gaaggtgtac tgatgaaccc gccaattaat tttttgccct ggcgacagca acgccggacc
    33961 gcttttcttc gtttctggtt gctgatgttc gttgcgcctt tgctgctggc cgtcgggata
    34021 acgctaatac tgcgtctgac aagcaatgcc gaagcacgcg taaacgccgt tttgcttcag
    34081 gcggaacaac aactcacccg cagcttacag ataacgaaac cacgtttgct ggaacgccag
    34141 cagttacgcg aacagcgttt gcaacgtcag cgccagcgac aatttacccg cgactggcaa
    34201 tctgcgctgg aagcactagc ggcgctttta cccgaacatg cctggctgac aacgataagc
    34261 tggcagcagg gaacgctgga gatcaagggg cttacaacaa gcattaccgc gttaaacgcg
    34321 ctggaaacgt cactccgcca ggatgcttct tttcatctca atcagcgggg ggccacgcag
    34381 caggatgcgc agggacgctg gcaatttgag tatcagttaa caaggaaggt tagcgatgaa
    34441 catgttcttt gactggtggt tcgccacatc actccgcctc cgccagcttt gctgggcagt
    34501 ctggttgctg gtgttagtta cgctcatttt tctgtcatcg acacaccagg aagagcgcga
    34561 cgcattaatt cgactacggg cgagtcatca ccagcagtgg gctgcactgt atcgcctggt
    34621 agacgccact cccttcagcg aagaaaaaac gctgcccttt tcgccactgg attttcagtt
    34681 atccggcgcg caactggttt cctggcatcc atccgcgcag ggtggtgagt tggcgttgaa
    34741 aacgctgtgg gaagcagtgc cgtcggcatt tacacggctg gcagagcgca acgtcagcgt
    34801 gagccgtttt tcgttaagcg tggaaggtga tgaccttttg ttcacgctac aactggagac
    34861 gccgcatgag ggttaaacgc tggttgttgg caggtattgc attgtgcctt ttaaccggta
    34921 tgcgtgaccc ttttaaaccg ccggaagatc tatgccggat tagcgaactt agccagtggc
    34981 gctatcaggg gatggtaggg cgaggcgagc gcatcatcgg tgtaataaaa gatgggcaaa
    35041 aaaaatggcg acgggtgcag caaaacgatg tgctggaaaa cggctggacg atcttacagc
    35101 tgacgccaga cgcactaacg ctgggaaccg ggacaaactg cgaaccgcca cactggttgt
    35161 ggcaacggca aggagataca aatgaagcaa tggatagccg cactactgtt gatgctgata
    35221 cccggcgtac aggcggcaaa gccgcaaaaa gtgacgctga tggtggatga cgttccggta
    35281 gctcaggtgt tgcaggcgct ggctgaacag gagaagttga acctggtggt ttcgccagac
    35341 gtcagcggta cggtgtcgtt acatttaact gacgttccct ggaagcaggc actacaaact
    35401 gtagtgaaaa gcgccggatt gataacgcgc caggagggca acattctctc ggtgcattcc
    35461 gttgcctggc agaatgacaa tatcgcccgc caggaggcgg agcagacgcg ggcgcaggca
    35521 aatctgccgc tggaaaatcg caatattact ctgcaatacg ccgacgccgg agagctggcg
    35581 aaagcggggg agaagctact gagtgccaaa gggagtatga ccgtcgataa acgcaccaat
    35641 cgccttttgc tgcgagataa caaaacggcg ttaagcacgc ttgaacagtg ggtatcgcaa
    35701 atggatctgc cggtcgggca ggttgagctg tcggcgcata ttgtcaccat taatgaaaaa
    35761 agtttgcgtg agttaggtgt gaaatggacg ctggccgatg cgcaacaagc tggtggcgtt
    35821 gggcaagtca ccacgcttgg cagcgacctc tccgtagcga cggcgacaac gcatatcggt
    35881 tttaacattg gacgcatcaa cggacgttta ctggatcttg agctttccgc gctcgaacaa
    35941 aaacagcagc tggatattat cgccagtccg cgtctgctgg cctcacatct tcagcctgcc
    36001 agcattaaac aggggagcga aattccatat caggtttcca gcggggaaag tggcgcgacg
    36061 tcggtggaat ttaaagaggc cgtcctgggg atggaagtca cgcccacggt gttacaaaaa
    36121 ggtcgcatcc ggctgaaatt acacatcagc cagaacgttc cggggcaggt gctacagcag
    36181 gcagatggcg aagtgctggc gattgataag caggagatcg aaacgcaggt cgaggtcaaa
    36241 agcggagaaa cgttggcgct gggcggcatt tttacccgta aaaataaatc gggtcaggat
    36301 agcgtaccgt tgcttggcga cattccctgg ttcgggcaat tatttcgtca tgacggaaaa
    36361 gaagatgaac gacgcgagtt agtggtgttt atcacgccac gactggtttc cagtgagtaa
    36421 acagccgtaa aagcggtaat gtttttacgc tgaacgtgtt tcatctattt gacgcgcgca
    36481 ggtatttagc atacaaggag taccgatttg agagttggtg ctcttcgctg cctgcgttcc
    36541 atgatgatga tttatcattc aggcggcatt ttgctgtctt ttttacgcta atcttacccg
    36601 gtgatttatc gccagagcgg tggtagcaag gcagcgcgct tgcagcgacc agatatgcag
    36661 agggatgggt gatttattca gttgccaaac ccgctggagt attgagataa ttttcagtct
    36721 gactctcgca atatcttatg aggtttcagt tcatgtcctg cggcgctctc tgagcgaagc
    36781 gggtttatca ttaacgaata gtcttagtag taccgaaaaa atggcagaga aacgcaatat
    36841 ctttctggtt gggcctatgg gtgccggaaa aagcactatt gggcgccagt tagctcaaca
    36901 actcaatatg gaattttacg attccgatca agagattgag aaacgaaccg gagctgatgt
    36961 gggctgggtt ttcgatttag aaggcgaaga aggcttccgc gatcgcgaag aaaaggtcat
    37021 caatgagttg accgagaaac agggtattgt gctggctact ggcggcggct ctgtgaaatc
    37081 ccgtgaaacg cgtaaccgtc tttccgctcg tggcgttgtc gtttatcttg aaacgaccat
    37141 cgaaaagcaa cttgcacgca cgcagcgtga taaaaaacgc ccgttgctgc acgttgaaac
    37201 accgccgcgt gaagttctgg aagcgttggc caatgaacgc aatccgctgt atgaagagat
    37261 tgccgacgtg accattcgta ctgatgatca aagcgctaaa gtggttgcaa accagattat
    37321 tcacatgctg gaaagcaact aattctggct ttatatacac tcgtctgcgg gtacagtaat
    37381 taaggtggat gtcgcgttat ggagaggatt gtcgttactc tcggggaacg tagttaccca
    37441 attaccatcg catctggttt gtttaatgaa ccagcttcat tcttaccgct gaaatcgggc
    37501 gagcaggtca tgttggtcac caacgaaacc ctggctcctc tgtatctcga taaggtccgc
    37561 ggcgtacttg aacaggcggg tgttaacgtc gatagcgtta tcctccctga cggcgagcag
    37621 tataaaagcc tggctgtact cgataccgtc tttacggcat tgttacaaaa gccgcatggt
    37681 cgcgatacta ctctggtggc gcttggcggc ggcgtagtgg gtgatctgac cggcttcgcg
    37741 gcggcgagtt atcagcgcgg tgtacgtttc attcaagtcc cgacgacgtt actgtcgcag
    37801 gtcgattcct ccgttggcgg caaaactgcg gtcaaccatc ccctcggtaa aaacatgatt
    37861 ggcgcgttct accagcccgc ttcagtggtg gtggatctcg actgtctgaa aacgcttccc
    37921 ccgcgtgagt tagcgtcggg gctggcagaa gtcatcaaat acggcattat tcttgacggt
    37981 gcgtttttta actggctgga agagaatctg gatgcgttgt tgcgtctgga cggtccggca
    38041 atggcgtact gtattcgccg ttgttgtgag ctgaaagcag aagttgtcgc cgccgacgag
    38101 cgcgaaaccg ggttacgtgc tttactgaat ctgggacaca cctttggtca ttccattgaa
    38161 gctgaaatgg ggtatggcaa ttggttacat ggtgaagcgg tcgctgcggg tatggtgatg
    38221 gcggcgcgga cgtcggaacg tctcgggcgg tttagttctg ccgaaacgca gcgtattata
    38281 accctgctca cgcgggctgg gttaccggtc aatgggccgc gcgaaatgtc cgcgcaggcg
    38341 tatttaccgc atatgctgcg tgacaagaaa gtccttgcgg gagagatgcg cttaattctt
    38401 ccgttggcaa ttggtaagag tgaagttcgc agcggcgttt cgcacgagct tgttcttaac
    38461 gccattgccg attgtcaatc agcgtaacaa caagaaaggt caggccgctt atcaagcggt
    38521 ctattagctt caggttaatt gcaacgtggt aagcattaac cttttagtgg ggtgttaaat
    38581 ggatgaattc aaaccagaag acgagctgaa acccgatccc agcgatcgtc gtactggtcg
    38641 ttctcgtcaa tcttctgaac gttctgagcg tactgaacgt ggcgaaccgc agatcaattt
    38701 tgatgatatt gaacttgatg acactgacga tcgccgtccg actcgtgcgc aaaaagcgcg
    38761 taatgaggaa ccggaaatcg aagaagaaat tgacgaatcc gaagatgaaa ccgtggatga
    38821 agagcgcgta gagcgtcgtc cgcgtaagcg taaaaaagca gccagtaaac ccgcttctcg
    38881 tcagtatatg atgatgggtg tcggcattct ggttctactg ctgttgatca tcggtatcgg
    38941 ttctgcgcta aaagccccct cgacctcttc cagcgatcaa actgcgtctg gcgagaagag
    39001 tattgatctt gcaggcaatg cgaccgatca ggccaatggc gtgcagccag cgccgggaac
    39061 cacgtctgcg gaaaatactc agcaggatgt ttctctgccg ccgatctctt ctacgccgac
    39121 tcaagggcaa accccggcgg caacggatgg tcaacaacgt gttgaagtgc agggtgacct
    39181 gaacaatgcg ctgacccagc cacaaaatca gcaacagttg aacaatgtgg cggtcaattc
    39241 tacattgccg accgaacccg caacggttgc gcctgttcgc aatggcaatg catcgcgtga
    39301 cacggcgaaa acgcaaaccg ctgaacgtcc ggccactacg cgcccagctc gtcagcaggc
    39361 ggtgattgaa ccgaaaaaac cgcaagcaac cgtgaaaacg gaaccgaagc cagtcgcaca
    39421 gacgccgaag cgaactgaac cagctgcccc tgtggcgagc acaaaggcac cggctgcgac
    39481 ttctacgcca gcaccaaaag agacggcgac tacggctcca gtacagacgg catccccggc
    39541 gcaaaccacg gcaacaccag ccgctggagg gaagaccgca ggtaatgttg gttcgttgaa
    39601 atcggcaccg tccagccatt acactctgca gctgagcagt tcctctaact acgacaacct
    39661 gaacggttgg gcgaagaaag agaatctgaa aaactacgtt gtctatgaaa cgacgcgtaa
    39721 tggtcagccg tggtatgtcc tggtttctgg cgtgtatgct tcgaaagaag aggcgaaaaa
    39781 agcggtatct acattgccag cagatgtcca ggccaaaaac ccgtgggcga aaccgctgcg
    39841 tcaggtacag gccgatctga agtaatcaag gttatctccc gcaatggttt atcattgcgg
    39901 gagttgcctg aagcgctgga tgctgtcgga gctttctcca cagccggaga aggtgtaatt
    39961 agttagtcag catgaagaaa aatcgcgctt ttttgaagtg ggcagggggc aagtatcccc
    40021 tgcttgatga tattaaacgg catttgccca agggcgaatg tctggttgag ccttttgtag
    40081 gtgccgggtc ggtgtttctc aacaccgact tttctcgtta tatccttgcc gatatcaata
    40141 gcgacctgat cagtctctat aacattgtga agatgcgtac tgatgagtac gtacaggccg
    40201 cacgcgagct atttgttccc gaaacaaatt gcgccgaggt ttactatcag ttccgcgaag
    40261 agttcaacaa aagccaggat ccgttccgtc gggcggtact gtttttatat ttgaaccgct
    40321 acggttacaa cggcctgtgt cgttacaatc tgcgcggtga gtttaacgtg ccgtttggcc
    40381 gctacaaaaa accctatttc ccggaagcag agttgtatca cttcgctgaa aaagcgcaga
    40441 atgccttttt ctattgtgag tcttacgccg atagcatggc gcgcgcagat gatgcatctg
    40501 tcgtctattg cgatccgcct tatgcgccgc tgtctgcgac tgccaacttt acggcgtatc
    40561 acacaaacag ttttacgctt gaacaacaag cgcatctggc ggagatcgct gaaggtctgg
    40621 ttgatcgcca tattccagtg ctgatctcca atcacgatac gatgttaacg cgtgagtggt
    40681 atcagcgcgc aaaattgcat gtcgtcaaag ttcgacgcag tataagcagc aacggcggca
    40741 cacgtaaaaa ggtggacgaa ctgctggctt tgtacaaacc aggagtcgtt tcacccgcga
    40801 aaaaataatt ctcaaggaga agcggatgaa acagtatttg attgccccct caattctgtc
    40861 ggctgatttt gcccgcctgg gtgaagatac cgcaaaagcc ctggcagcgg gtgcagatgt
    40921 cgtgcatttt gacgtcatgg ataaccacta tgttcccaat ctgacgattg ggccaatggt
    40981 gctgaaatcc ttgcgtaact acggcattac cgcccctatc gacgtacatc tgatggtgaa
    41041 acccgtcgat cgcattgtgc ctgatttcgc tgccgctggt gccagcatca ttacctttca
    41101 tccagaagcc tccgagcatg ttgaccgcac gctgcaactg attaaagaaa atggctgtaa
    41161 agcgggtctg gtatttaacc cggcgacacc attgagctat ctggattatg taatggacaa
    41221 gctggatgtg atcctgctga tgtctgttaa ccctggtttc ggcggtcagt ctttcattcc
    41281 tcaaacactg gataaactgc gcgaagtacg tcgtcgtatc gacgagtctg gctttgacat
    41341 tcgactggaa gtggacggtg gcgtgaaggt gaacaacatt ggcgaaatcg ctgcggcggg
    41401 cgcggatatg tttgttgctg gttcggcaat cttcgaccag ccagactaca aaaaagtcat
    41461 tgatgaaatg cgcagtgaac tggcaaaggt aagtcatgaa taagtttgaa gatattcgcg
    41521 gcgtcgcttt tgatctcgac ggtacgctgg ttgacagtgc acccggtctt gctgctgcgg
    41581 tagatatggc gctgtatgcg ctggagttgc ctgtcgcagg tgaagaacgc gttattacct
    41641 ggattggtaa cggcgcagat attctgatgg agcgcgcatt gacctgggcg cgtcaggaac
    41701 gtgcgactct gcgtaaaaca atgggtaaac cgcccgttga tgacgacatt ccggcagaag
    41761 aacaggtacg tattctgcgt aaactgttcg atcgctacta tggcgaggtt gccgaagagg
    41821 ggacgttttt gttcccgcat gttgccgata cgttgggcgc gttgcaggct aaaggcctgc
    41881 cgctaggcct ggtcaccaac aaaccgacgc cgttcgtcgc gccgctgctc gaagccttag
    41941 atatcgccaa atacttcagc gtggtgattg gtggtgatga tgtgcaaaac aaaaaaccgc
    42001 atccggaccc gctgttactg gtggctgaac ggatgggcat tgctccacaa cagatgctgt
    42061 ttgttggcga ctcacgcaat gatattcagg cagcaaaagc ggcaggttgc ccatcagttg
    42121 gcttaaccta cggatataac tacggcgagg ctatcgatct cagccagcct gatgtaattt
    42181 atcagtctat aaatgacctt ctgcccgcat tagggcttcc gcatagcgaa aatcaggaat
    42241 cgaaaaatga ctaagcccat cgtttttagt ggcgcacagc cctcaggtga attgaccatt
    42301 ggtaactaca tgggtgcgct gcgtcagtgg gtaaacatgc aggatgacta ccattgcatt
    42361 tactgtatcg ttgaccaaca tgcgatcacc gtgcgccagg atgcacagaa gctgcgtaaa
    42421 gcgacgctgg atacgctggc gttgtatctg gcttgtggta tcgatcctga gaaaagcacc
    42481 atttttgttc agtcccacgt gccggaacat gcgcagttag gctgggcatt gaactgctat
    42541 acctacttcg gcgaactgag ccgcatgacg cagtttaaag ataaatctgc gcgttatgcc
    42601 gagaacatca acgctggtct gtttgactat ccggtgctga tggcagcgga catcctgctg
    42661 tatcaaacaa atctggtacc ggtgggtgaa gaccagaaac agcacctgga actgagccgc
    42721 gatatcgccc agcgtttcaa cgcgctgtac ggcgatatct ttaaggtgcc agagccgttt
    42781 attccgaaat ctggcgcgcg cgtaatgtcg ctgctggagc cgaccaagaa aatgtccaag
    42841 tctgacgata accgcaataa cgttatcggc ctgctggaag atccgaaatc ggtagtgaag
    42901 aaaatcaaac gcgcggtcac tgactccgac gagccgccag tagttcgcta cgatgtgcag
    42961 aacaaagcgg gcgtttccaa cctgctggat atcctttctg cggtaacggg ccagagcatc
    43021 ccggaactgg aaaaacagtt cgaaggcaag atgtatggtc atctgaaagg tgaagtggct
    43081 gatgccgttt ccggtatgct gactgaattg caggaacgtt accaccgttt ccgcaacgat
    43141 gaagccttcc tgcaacaggt gatgaaagac ggcgcagaaa aagccagcgc acacgcttcc
    43201 cgtacgctaa aagcggtgta cgaagcgatt ggttttgtgg cgaagccgta atttaacatt
    43261 aatgccaaaa aaaccgggga aacccggttt ttttatcctc atttgcaata atccgaaaaa
    43321 atgtgaagcg cctcgccgtt tccacatctc gctgttgcgc cttatcttca aattcatgaa
    43381 gatataaaca ttcattttat tgaaaatata ttatgcgtcg aacgtttatc aaaaaagaag
    43441 gcgtcgttat cacgacactg gcccgttatt tgttgggtga aaagtgcggt aatcgactga
    43501 aaaccataga tgagctggca actgaatgcc gttcatcggt tggcctgacg caggccgcgt
    43561 tgaaaacgct ggaatcaagc ggagcgatac ggattgaacg ccgtgggcgc aatggcagtt
    43621 atctggttga gatggataac aaagcattgc tgactcatgt ggatatcaac aacgtggtat
    43681 gtgcgatgcc cttgccctat acccgtttgt acgaaggcct ggcgagcgga ttgaaagccc
    43741 agtttgatgg cattcctttt tactatgcgc atatgcgcgg cgcggatatt cgcgtggagt
    43801 gtttacttaa cggcgtgtat gacatggcgg tggtttcgcg actggcggcg gaaagttatc
    43861 tcacgcaaaa aggattatgc ctcgcgctgg agttgggacc gcatacctac gttggcgagc
    43921 accagttgat ttgccgtaaa ggcgagtccg caaacgtgaa gcgcgtgggg ctggataacc
    43981 gttcggcgga tcagaaaatc atgaccgatg tcttttttgg cgatagtgat gtggaacgag
    44041 tcgatctctc ttatcacgag agtttacaac gcattgttaa aggcgatgtt gacgcggtta
    44101 tctggaacgt agtggcggaa aacgaactga ccatgctggg attagaagcg acgccgctca
    44161 cagacgatcc gcgattttta caggccaccg aagccgtggt cctgacgcga gtcgatgatt
    44221 acccaatgca acaactgctg cgtgcagttg ttgataaaca tgccctgctt gctcatcaac
    44281 agcgagtagt cagtggggaa caggaaccca gttattaaac gaaaggcatc tgatatggaa
    44341 accagactca acctgctttg cgatgcaggc gttattgata aggacatctg caaaggcatg
    44401 atgcaggtcg tcaatgtact ggaaacagag tgccatctac cggtgcgcag tgagcaagga
    44461 acgatggcga tgacacatat ggcgagtgca ctgatgcgca gtcgccgtgg tgaagaaata
    44521 gagccgctgg atgacgaatt gctggcggaa ctggcgcaat ccagccactg gcaagccgtt
    44581 gtgcaattgc atcaggtatt gttgaaggaa tttgcactgg aagttaaccc gtgtgaagaa
    44641 ggctatttgc tggccaacct ttatggatta tggatggctg ctaacgaaga ggtttgaagc
    44701 tcccgataaa tccacgtcgt acaacctaaa tattcaaaaa aatgaatatt taattcaagg
    44761 aacagaaacg aggcaacaag atgtttgtag aagcattgaa acgccagaac ccggcgctga
    44821 tttccgccgc actaagtttg tggcagcagg gcaagatcgc cccggacagt tgggtgatcg
    44881 acgtggatca agttctggaa aacggcaagc ggctgattga gacggcgcgg ctttacggca
    44941 ttgaactgta tctgatgacc aaacaattcg gtcgtaatcc gtggctggca gaaaaactgc
    45001 tggctctggg ctacagcggc attgtggcgg tggattacaa agaggcgcga gtcatgcgcc
    45061 gcgccggttt gccggtagcg catcaggggc atctggtaca aatcccttgt catcaggttt
    45121 ctgacgccgt tgaacaggga accgacgtca tcactgtgtt taccctcgac aaagcgcggg
    45181 aaatttctgc ggcagcggtg aaggccggac gtgtgcagtc tgtgctgctc aaagtttata
    45241 gcgacgatga ttttctttat ccggggcagg agagcggttt tgtacagcat tcgctgcacg
    45301 aggtggttgc tgaaatccag aatctgccgg ggctacattt ggcgggactt acccatttcc
    45361 cttgcctgct ttgggatgag gctgccggga aagttttgcc gacaccgaat cttcacacgc
    45421 tggtacaagc acgggatcaa ctggcgaaat ctggtattgc gattgagcaa ctgaacgcgc
    45481 cttcagcgac cagctgcacg tcgctgccat tgctggtgga atacggtgtg actcataccg
    45541 aacccggtca tgcgctgacg ggcactattc cggcaaacca gcggggcgat cagcctgaac
    45601 gtatcgcgat gctctggtta agtgaaatct cccatcattt ccgtggcgac agctactgct
    45661 acggcggcgg ttactaccgt cgtggtcacg cgcaacatgc gctggtgttt acgccagaaa
    45721 atcaaagaat tactgaaaca tatctcaacg ccgtggatga cagcagtatc gactacaccc
    45781 tgccgctggc aggcgagcat ccggtaagca gtgcagtggt gctctgtttt cgcacgcaga
    45841 tttttatcac ccgtagcgat gtggtgttgg tgtccggtat tcaccatggc gaaccagaaa
    45901 tagttggtcg ttatgacagc ctcggcaacc ctctggaggc gtaaatggcg cgatttgtgg
    45961 tgttagtgat tgatagcttt ggcgtagggg caatgaaaga tgtcacgttg gtgcgtccgc
    46021 aggatgccgg ggcgaatacc tgtggtcaca tcctgagcca gttgccgcat ttgcagctac
    46081 caacgctgga gacgctgggg ctaatcaacg cattgggtta tgcgcctggc gatatgcagc
    46141 cgtcagactc cgcaacctgg ggcgtggcag agctgcaaca tgaaggtggc gataccttta
    46201 tggggcatca ggaaatttta ggtacgcgcc cattaccgcc gctgcggatg ccctttcgtg
    46261 atgtgattga ccgtgttgag caggcattag tttccgctgg ctggcaggtt gagcgtcgtg
    46321 gcgatgatct gcaatttctg tgggtcaatc aggcggttgc gattggcgat aatctcgagg
    46381 cggatttagg tcaggtctat aacatcaccg ccaatctctc tgtgatctct tttgacgacg
    46441 caatcaaaat gggtcgtatc gtgcgtgagc aggtacaggt cggtcgggtc attacatttg
    46501 gtggcctgtt aaccgacagc cagtgcatcc tcgatgccgc agaaagcaaa gaagggcgct
    46561 ttattggtat caatgcgccg cgttctggcg cctatgacaa cggtttccag gtcgtacata
    46621 tgggctacgg tgtcgatgaa aaagtgcagg tgccgcaaaa actgtatgaa gcgggcgtgc
    46681 caaccgtgct ggtgggtaag gtggcagata tcgtcagcaa tccttatggc gtgagctggc
    46741 aaaacctggt ggatagccag cggattatgg atatcaccct caacgaattt aacacctatc
    46801 cgacggcgtt tatttgtacc aatatccagg aaaccgacct cgctggtcat gcagaagacg
    46861 tcgcacgtta tgccgaacgt ttgcaggtcg ttgaccgtaa ccttgcccgg cttgttgagg
    46921 cgatgcagcc agatgattgc ctggtcgtga tggcggatca cggtaacgat ccgaccatcg
    46981 gtcacagcca ccatacccgc gaagtggtgc cagtgctggt ttatcagcaa ggactggtcg
    47041 ctacgcagct cggtgtgcgc accacgcttt ctgatgtggg ggctaccgtg tgtgaatttt
    47101 tccgtgcgcc accgccacaa aatggtcgct cttttctttc ctccttccgg tttgcaggag
    47161 acaccctatg agttttgatc cgacgggcta caccctcgcc catgagcatc tgcatattga
    47221 tctttccggc tttaaaaaca acgtggactg ccgccttgat cagtatgcgt tcatttgcca
    47281 ggagatgaac gacctgatgg cccggggcgt gcgtaatgtg attgagatga ccaaccgtta
    47341 catggggcgc aatgcgcaat ttatgctcga tgtaatgcgc gaaaccggga tcaacgtggt
    47401 gggctgtacc ggttattacc aggacgcgtt tttcccggaa catgtggcga cccgcagcgt
    47461 gcaggaactg gcgcaggaga tggtcgatga aattgagcag ggtatcgatg gcactgacct
    47521 gaaagccgga attatcgcgg agatcggctc cagcgaaggg aagattacgt cgctggaaga
    47581 gaaggtgttt attgccgccg cgctggcgca taaccagacc ggacgcccga tctccacgca
    47641 tacgtcgttc agcacgatgg ggctggagca actggctctg ttgcaagccc acggagttga
    47701 tctttcgcgc gtcaccgtcg gccactgcga tctgaaagac aatctcgaca acattttgaa
    47761 gatgatcgat ctcggcgcgt atgtgcagtt cgacaccatc ggcaagaaca gttactaccc
    47821 ggacgaaaag cgcattgcga tgctccatgc gctacgtgac cgtgggttgc tgaaccgcgt
    47881 catgctgtcg atggatatta cgcggcgctc tcatttaaaa gccaacggtg gttatggcta
    47941 tgacttttta ttgaccacct ttattccgca attgcgccag tcaggattca gtcaggccga
    48001 tgtggatgtg atgttacgtg aaaatccctc tcaatttttc caataaggac agactcatga
    48061 aaaagattgg cgttgcaggc ttacagcgtg agcagattaa aaaaaccatt gaagcgacgg
    48121 ctcctggctg ttttgaagtt ttcattcaca acgacatgga agcggcaatg aaagtgaaat
    48181 ccggacaact ggattactac atcggcgcgt gtaataccgg tgcgggcgca gccttgtcga
    48241 ttgctatcgc ggtgattggc tataacaaaa gttgcaccat tgccaagccg ggcattaaag
    48301 cgaaagacga acatatcgcc aaaatgatcg ctgaaggaaa agtggcgttt ggcctttccg
    48361 ttgagcacgt tgaacacgcg attccgatgc tgattaacca tctaaaataa aaggcacgac
    48421 tatggatctg tatattcaga ttatcgtggt ggcgtgcctg acgggtatga catcgcttct
    48481 ggcgcatcgc tcggcggccg tttttcatga cggtatccgc ccgatcctgc cacaactgat
    48541 tgaaggctat atgaaccgtc gcgaggcggg gagcatcgct tttggtctga gcattggttt
    48601 tgtggcctcg gtggggatct cttttaccct gaaaaccggg ctgctcaacg catggttact
    48661 ctttcttcct accgatatcc tcggcgtact ggcgataaac agcctgatgg cgtttggtct
    48721 tggtgctatc tggggaatat tgatcctcac ctgtctgttg ccagtaaacc agctgctgac
    48781 cgcgctaccg gtggatgtat taggtagcct gggggaatta agctcgccgg tggtttcagc
    48841 ttttgcactg ttcccgttgg tggcgatttt ctaccagttt ggctggaagc aaagtctgat
    48901 cgccgccgtg gtggtactga tgactcgtgt ggtggtagta cgctatttcc cacatcttaa
    48961 ccctgaatcc atcgaaatct ttattggcat ggtgatgctg ctggggatcg caataactca
    49021 tgacctgcgt catcgtgatg aaaatgatat cgatgccagc ggtatgtcgg tgtttgaaga
    49081 gcgtacatca cggattatca aaaacttacc gtatatcgcc atcgtgggtg cattgattgc
    49141 tgccgttgcc agcatgaaga ttttcgccgg tagtgaagtg tcgatcttca cactggagaa
    49201 agcgtactcc gcaggcgtaa cgccggaaca atcgcaaaca ctaatcaacc aggcggcact
    49261 ggcagaattt atgcgcgggc tgggttttgt gccgttgatt gccaccacgg cgttagccac
    49321 cggcgtgtat gcagttgcgg gctttacctt tgtttatgcg gtgggctatc tctcgccgaa
    49381 tccgatggtt gcagcggtat taggcgcagt ggttatttcg gcggaagtct tgctgcttcg
    49441 ttctatcggc aaatggttgg ggcgctaccc gtcggtacgt aatgcgtcgg ataacatccg
    49501 taacgccatg aatatgctga tggaagtggc gttgctggtc ggttcgatct ttgcagcaat
    49561 caaaatggcg ggctataccg gattctctat cgcggttgcc atttacttcc tcaacgaatc
    49621 cctgggccgt ccggtacaga aaatggcggc accggtcgtg gcagtaatga tcaccggcat
    49681 cctgctgaat gttctttact ggcttggcct gttcgttccg gcttaaggaa ggcacctatg
    49741 aagacgtttc ctctgcaaag cctgacgctt attgaggcgc agcaaaagca gtttgcgctg
    49801 gtggacacga tttgccgtca ttttcctggc agcgagtttc ttacctgcgg tgatttgggc
    49861 ttaacgccgg ggctaaatca gccccgcatt acccagcgtg tggaacaggt gctggctgac
    49921 gcgtttcacg cacaggccgc ggcgctggta cagggcgcgg gtactggcgc gatccgtgcg
    49981 gcgctggcag ctttgctcaa atcggggcag cgtcttctgg tgcatgacgc gccggtttat
    50041 ccaacgacgc gcgtcattat tgagcagatg gggctaacgc tcattacggc tgatttcaat
    50101 gatctgtcgg cactgaagca ggttgttgac gagcaacaac ctgatgccgc gctggtgcag
    50161 catacgcgcc agcagccgca ggaccgctat gtgctggcag acgtgctggc aacgttgcgc
    50221 gcggcaggtg ttccagcgtt aaccgatgac aactatgcgg tgatgaaggt agcgcgaatc
    50281 ggctgcgaat gcggggcgaa tgtgtcgaca ttttcctgct tcaagctatt tgggccagag
    50341 ggcgttggtg cggtggtagg cgatgccgat gttattagcc ggattcgcgc cacgctctat
    50401 tccggcggca gtcagattca gggggcgcag gcattagagg tgttgcgtgg tctggtgctc
    50461 gcgccagtga tgcacgcggt gcaggcgggg gtatctgaac ggttgctggc tttgcttaac
    50521 ggcggcgcgg tggcggaagt gaaaagcgcc gtcattgcca atgcacagtc gaaggtattg
    50581 attgtggagt ttcatcagcc gattgccgcc agagtgctgg aagaggcgca gaaactcggt
    50641 gccttgcctt acccggttgg tgcagagtcg aaatatgaaa tcccgccgct cttttatcga
    50701 ctttccggaa cgtttcgcca ggcgaatccg cagttagaac attgcgcgat tcgcattaac
    50761 ccaaatcgcg gcggtgaaga gacgatattg cggatcttgc gtgaaagtat tgccagcatt
    50821 taatcgttgt aaacgatatt ttcgaaaaga atgcagaaac aaatacgccc tcggataact
    50881 ccgagggcgt caggcaatta aaccggcgtt agccgatttc tgtcagagac ttactgtgca
    50941 gtcggaccgc aaccgccaat gattttagaa atagaaattg ccgggtgcag caggtagtcg
    51001 taagagcagt tcttatcacg gttttcaata tgaccagtac atgcagttaa cgtagccagt
    51061 actgcgccta ccagtgcaac tttaataaat ttgttcattt acattcccta tgtattatat
    51121 attaattaat attcattgat tatatgaata taa
//
LOCUS       DAPOXO010000029        50514 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPOXO010000029 DAPOXO010000000
VERSION     DAPOXO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 50514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50514
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.029"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(58..840)
                     /locus_tag="ROH59_002043"
     CDS             complement(58..840)
                     /locus_tag="ROH59_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX4804526.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDL
                     FGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLPCTGVVHGFS
                     GSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     QPNRPEQAVRVFDVLCELRPEPEDEIAEVLLNNTYALFSVSG"
     gene            complement(837..1910)
                     /locus_tag="ROH59_002044"
     CDS             complement(837..1910)
                     /locus_tag="ROH59_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HDX4804527.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAFICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTCHLVPVVTPESIVIPPAPVAND
                     TLVAEVSDAPQANDPTFNNEDLA"
     gene            complement(2032..2193)
                     /locus_tag="ROH59_002045"
     CDS             complement(2032..2193)
                     /locus_tag="ROH59_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HDX4804528.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            complement(2320..2925)
                     /gene="osmY"
                     /locus_tag="ROH59_002046"
     CDS             complement(2320..2925)
                     /gene="osmY"
                     /locus_tag="ROH59_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HDX4804529.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            complement(3318..4907)
                     /gene="prfC"
                     /locus_tag="ROH59_002047"
     CDS             complement(3318..4907)
                     /gene="prfC"
                     /locus_tag="ROH59_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDX4804530.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWA
                     PAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     SRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSM
                     VNLRLAQERYPDVQFHQTREH"
     gene            complement(4998..5675)
                     /gene="yjjG"
                     /locus_tag="ROH59_002048"
     CDS             complement(4998..5675)
                     /gene="yjjG"
                     /locus_tag="ROH59_002048"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HDX4804531.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGVITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHHREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            complement(5690..6136)
                     /gene="rimI"
                     /locus_tag="ROH59_002049"
     CDS             complement(5690..6136)
                     /gene="rimI"
                     /locus_tag="ROH59_002049"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDX4804532.1"
                     /translation="MNTISSLETTDLPAAFHIEQRAHTFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            complement(6105..6518)
                     /gene="holD"
                     /locus_tag="ROH59_002050"
     CDS             complement(6105..6518)
                     /gene="holD"
                     /locus_tag="ROH59_002050"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HDX4804533.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPPHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VTSPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            6621..7652
                     /gene="rsmC"
                     /locus_tag="ROH59_002051"
     CDS             6621..7652
                     /gene="rsmC"
                     /locus_tag="ROH59_002051"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HDX4804534.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLNRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDANKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANSVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
     gene            7852..7938
                     /locus_tag="ROH59_002052"
     tRNA            7852..7938
                     /locus_tag="ROH59_002052"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7886..7888,aa:Leu,seq:cag)
     gene            7967..8053
                     /locus_tag="ROH59_002053"
     tRNA            7967..8053
                     /locus_tag="ROH59_002053"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8001..8003,aa:Leu,seq:cag)
     gene            8088..8174
                     /locus_tag="ROH59_002054"
     tRNA            8088..8174
                     /locus_tag="ROH59_002054"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8122..8124,aa:Leu,seq:cag)
     gene            complement(8213..8449)
                     /locus_tag="ROH59_002055"
     CDS             complement(8213..8449)
                     /locus_tag="ROH59_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HDX4804535.1"
                     /translation="MLQRTLGSGWGVLLPGLLITGLMYADLSPDQWRIVILMGLVLTP
                     VMLYHKQLRHYVLLPSCLALIAGIMLMIMNLNQG"
     gene            8590..9378
                     /gene="fhuF"
                     /locus_tag="ROH59_002056"
     CDS             8590..9378
                     /gene="fhuF"
                     /locus_tag="ROH59_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HDX4804536.1"
                     /translation="MAYRSAPLYEDVIWRTHLQPQDAGLAQAVRATIAKHREHLLEFI
                     RLDEPAPLNAMTLAQWSSPNALSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVSPEHFHAEFHETGRAACFWVDVCDDKNATPHSPQQRMETL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHAIFFEK
                     TLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            complement(9416..10093)
                     /gene="bglJ"
                     /locus_tag="ROH59_002057"
     CDS             complement(9416..10093)
                     /gene="bglJ"
                     /locus_tag="ROH59_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HDX4804537.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQ
                     ESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEA
                     SNVLHPY"
     gene            complement(10051..10776)
                     /locus_tag="ROH59_002058"
     CDS             complement(10051..10776)
                     /locus_tag="ROH59_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDX4804538.1"
                     /translation="MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDL
                     TLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLM
                     CPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
                     VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELN
                     LPSVYGDAAEWNTAELRREMSHS"
     gene            11397..12167
                     /locus_tag="ROH59_002059"
     CDS             11397..12167
                     /locus_tag="ROH59_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDX4804539.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNNGGWDGAVITFFASTTAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSDTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            12158..12631
                     /locus_tag="ROH59_002060"
     CDS             12158..12631
                     /locus_tag="ROH59_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HDX4804540.1"
                     /translation="MGVIEFLFALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            12738..13277
                     /gene="dnaT"
                     /locus_tag="ROH59_002061"
     CDS             12738..13277
                     /gene="dnaT"
                     /locus_tag="ROH59_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HDX4804541.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            13280..14017
                     /gene="dnaC"
                     /locus_tag="ROH59_002062"
     CDS             13280..14017
                     /gene="dnaC"
                     /locus_tag="ROH59_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HDX4804542.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            14066..14560
                     /locus_tag="ROH59_002063"
     CDS             14066..14560
                     /locus_tag="ROH59_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HDX4804543.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            14814..17105
                     /gene="opgB"
                     /locus_tag="ROH59_002064"
     CDS             14814..17105
                     /gene="opgB"
                     /locus_tag="ROH59_002064"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HDX4804544.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLTWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHVDKTTWKSKTAFKDTVIDMARYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(17245..18267)
                     /gene="lgoD"
                     /locus_tag="ROH59_002065"
     CDS             complement(17245..18267)
                     /gene="lgoD"
                     /locus_tag="ROH59_002065"
                     /EC_number="1.1.1.414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-galactonate oxidoreductase"
                     /protein_id="HDX4804545.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGNQPFFSYPRVLGHEICGEVVGLGKNVADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAETYERDVINNRELI
                     KGVITF"
     gene            18406..19320
                     /locus_tag="ROH59_002066"
     CDS             18406..19320
                     /locus_tag="ROH59_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313344.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDX4804546.1"
                     /translation="MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTT
                     VRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQR
                     QLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIQSEKRGQWSMKQFDQSYAEQL
                     FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHS
                     LLLSAADNIFFEQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLD
                     ATLALRNHLNSAKQSMIRSINENMRYAH"
     gene            19537..20898
                     /locus_tag="ROH59_002067"
     CDS             19537..20898
                     /locus_tag="ROH59_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4804547.1"
                     /translation="MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAM
                     LLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLD
                     RKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
                     IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYR
                     NREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLY
                     LAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKIC
                     IIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV
                     GSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDP
                     RKD"
     gene            complement(20947..22611)
                     /gene="tsr"
                     /locus_tag="ROH59_002068"
     CDS             complement(20947..22611)
                     /gene="tsr"
                     /locus_tag="ROH59_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HDX4804548.1"
                     /translation="MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQ
                     TIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAE
                     KNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
                     DGFEKQYVAYMEQNDRLHDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASL
                     VAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA
                     IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSAS
                     ETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQ
                     GRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVT
                     RVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRL
                     TEAVAVFRIQQQQQQQRETSAVVKTVMPAAPRKMAVADSGENWETF"
     gene            22988..25138
                     /gene="btsT"
                     /locus_tag="ROH59_002069"
     CDS             22988..25138
                     /gene="btsT"
                     /locus_tag="ROH59_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HDX4804549.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            25188..25391
                     /locus_tag="ROH59_002070"
     CDS             25188..25391
                     /locus_tag="ROH59_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDX4804550.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            25402..26358
                     /gene="yjiA"
                     /locus_tag="ROH59_002071"
     CDS             25402..26358
                     /gene="yjiA"
                     /locus_tag="ROH59_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HDX4804551.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVISTKPRFHFIA
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK"
     gene            complement(26392..26694)
                     /locus_tag="ROH59_002072"
     CDS             complement(26392..26694)
                     /locus_tag="ROH59_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HDX4804552.1"
                     /translation="MSMVKHKRGTPSTLDVQHEAELKALANKFDEDIDYSDIPPSSDE
                     QWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLRDQNKK"
     gene            complement(26681..26968)
                     /locus_tag="ROH59_002073"
     CDS             complement(26681..26968)
                     /locus_tag="ROH59_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HDX4804553.1"
                     /translation="MPMEFEWDANKAKSNRVKHGIRFEDAVLVFDDPQHLSQQDRIEN
                     GEYRWQTIGLVHGIVVILVAHTIRFESGNEIIRIISARKADRKERSRYEHG"
     gene            27165..28331
                     /locus_tag="ROH59_002074"
     CDS             27165..28331
                     /locus_tag="ROH59_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HDX4804554.1"
                     /translation="MKNYKVITPLFPTYAQVKAMMKAVSGYSLKAVRNMITAIRDQTG
                     TPQKPVDWSEPDLWISERLTGEDADIARRIWDTDNHILNPRHSYGCYLFLNYPQFELM
                     ESTPDDTWQPTSRGQKFLQDDEKTLRSLDDQEGILQLLELLAGREMSRRADLLPEWQA
                     FLHQHSKFASASSVKSTLYSRLYNLIDRGMVTREGMSYCITDTGRAWLGKALPARKSD
                     PRKELLEAVKRYNEQQKELLREQISTMNPYKFEQLVGQLLEAMGYEQVEVTKASGDKG
                     VDVIGQVQVGITTITEVVQVKRMQNTITRPYIDQLRGALPYHKAIRGTLITTGKFAAK
                     CAEAALFPGAAPITLIDGDRLLELLIENNVGIRRSNAVELLDVDLQLFDELEMD"
     gene            28395..30014
                     /locus_tag="ROH59_002075"
     CDS             28395..30014
                     /locus_tag="ROH59_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003845607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDX4804555.1"
                     /translation="MAKAPTKKAKAKKGFEETLWDTANQLRGSVESSEYKHVVLSLVF
                     LKFISDKFEARRKKMIADGQADFLEMEVFYQQDNIFYLPEEARWSFIKQNAKQDDIAV
                     RIDTALSTIEKRNPTLKGALPDNYFSRQNLETKKLASLIDTIDNIETLAHETDVETLS
                     KEDLVGRVYEYFLGKFAATEGKGGGEFYTPKCVVTLLTEMLEPFQGKIYDPCCGSAGM
                     FVQSVKFVESHQGKSRDIALYGQELTATTYKLAKMNLAIRGLSANLGERPANTFFSDQ
                     HPDLKADYILANPPFNLKDWRNEAELTEDPRFAGYRMPPTGNANYGWILHMLSKLSAN
                     GTAGFVLANGSMSSNTSGEGEIRAQMIENDLIDCMIALPGQLFYTTQIPVCLWFMTKS
                     KAADPAKGYRDRQGETLFIDARNLGTMISRTTKELTAEDIATIADTYHAWRSTPEELA
                     ARIARGDSKLEKYEDQAGFCKVATLQDIKDNDYVLTPGRYVGAAEQEEDGVAFETKMR
                     ELSKTLFEQMKQAEELDRAIRQNLEALGYGE"
     gene            30004..31308
                     /locus_tag="ROH59_002076"
     CDS             30004..31308
                     /locus_tag="ROH59_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000535012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDX4804556.1"
                     /translation="MGSKWCIYRLGDIAEFSYGKMPKKEFVGTGDYVIFSGYKYTESY
                     PEKNTSAGELIVVARGVGGTGDVKITTRDCYLTNLSIKINLDETKVRKEYFYYLFLQS
                     NLRYLDSGSAQSQITINDLANVEISAPSLNVQDLIVKSLKAFDDKITTLSSMNQTLEQ
                     MSQTLFKSWFVDFDPVIDNALDAGNPIPEALQTRAKLRQKVRNSADFKPLPAEIRSLF
                     PSEFEETELGWVPKGWKEGTLPEIAFINSTSWTNKNQPDYINYVDLSNAKDGRIYSIE
                     KLSFNDAPSRARRILKKDDLIFGLVRPANRSFAYVHVDGLTGSTGFAVIRAQKTIYKN
                     FIYYFVTYDKNIEELARIADGGAYPAIKPDDICTLPLIIPSINIIEKFDELTSNFREM
                     MNNSLIQNEYLTNLRGTLLPKLISGELSLEDLPDLTTDTEAA"
     gene            31403..34666
                     /locus_tag="ROH59_002077"
     CDS             31403..34666
                     /locus_tag="ROH59_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDX4804557.1"
                     /translation="MSLSFSEAKLEQAIIELLQDQGYQHLIGDNVPRSSLDQVIIEDD
                     LRHYLAARYQPDGITEEEIQRLIKQFTTLPASDLYESNKTFCRWLANGFLFKRDDRQQ
                     KDLYIELLDTRHLPAALRQIFDAEDVPLQQAAELPPSYMNPPLNRIKIVNQLKISGKD
                     NQTRIPDGILYINGLPLVVFEFKSAVREQEASIGDAWKQLCKRYRRDIPQLFIYNALC
                     IISDGVNNRMGNLFAPYEYFYSWRKVTGNENREQDGIPSLHSMIQGLFHPVRLLDVIK
                     NFICFPDKAKHEVKICCRYPQYYAARKLYYSIKQARKPFGSGKGGTYFGATGCGKSYT
                     MQFLTRLLMKSVEFASPTIVLITDRTDLDDQLSAQMCNAKNYIGDDTIVPVTSREDLR
                     NQLAGRNSGGVFLTTIHKFTEDTELLSERNNIICISDEAHRSQVNLDQKVIVDKESGK
                     VRKTYGFAKYLHDSLPNATYVGFTGTPIDATLDVFGEVIDSYTMTESVQDEITVRIVY
                     EGRAAKVILDSSKLEEVEKYYEECANAGTNEWQIDESKKATATMNAVLGDEDRLKALA
                     EDFAKHYEKRVAEGSTVKGKAMFVCASREIAWDFYRQLKAIRPAWFEVKQAPDGVVLT
                     EQEQKELPPSEMVKMVMTRGKDDDEALYDLLGTKEYRKELDKQFKNAKSNFKIAIVVD
                     MWLTGFDVPELDTIYIDKPLQKHNLIQTISRVNRKLEGKSKGLVVDYIGIKSQMNQAL
                     AMYSRIDATNFEDIQQSVIEVKNHLDLLGQVFYEFDSRDYFSGEPQAQLSCLNRAAEF
                     VLRTQKVERRFMGLVKRMKAAYDVCCGSEALSQTERDYIHYYLAVRSIVFKLTKGDAP
                     DVTQMNARVREMIAEALKADGVEEIYFLGDKKAESIDIFDEDYLARINKIKLPATKIQ
                     LLQKLLEKAISDFKKVNQLQGINFTRRFQAIIDRYNERREDDVLNGEEFDTFSQEMTD
                     IIYDIKTEMGTWADLGIDIEEKAFFDILAHMRDKYQFTYDDEKMLSLAKEMKSVVDNT
                     SKYPDWSKRDDIKAKLKVELILLLHKHKFPPVANDDVYMGVLAQAENFKEHHMSSLN"
     gene            34881..35219
                     /gene="symE"
                     /locus_tag="ROH59_002078"
     CDS             34881..35219
                     /gene="symE"
                     /locus_tag="ROH59_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001534835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease SymE"
                     /protein_id="HDX4804558.1"
                     /translation="MTDTHSIALPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKG
                     QWLETAGFATGTAVDVKVMEGCIVLTAQPPAIEESELMQSLRQVCKLSVRKQRQVQEF
                     IGVISSKTPR"
     gene            complement(35262..35426)
                     /locus_tag="ROH59_002079"
     CDS             complement(35262..35426)
                     /locus_tag="ROH59_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1127 domain-containing protein"
                     /protein_id="HDX4804559.1"
                     /translation="MEFYENKAKTPFIRLVQLWQAVRRWRRQMQTRRVLQQMSDERLR
                     DIGLRREDVE"
     gene            35603..37015
                     /locus_tag="ROH59_002080"
     CDS             35603..37015
                     /locus_tag="ROH59_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDX4804560.1"
                     /translation="MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQ
                     QAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDQVLDMLEAHS
                     DSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLML
                     DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIE
                     IPTDPETGISVEALELALEQWPIKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIV
                     IFEDDVYGELATEYPRPRTIHSWDIDGRVLLCGSFSKSIAPGLRVGWVAPGRYHDKLL
                     HMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIREYFPCEIC
                     ITRPKGGFLLWIELPEQVDMVCVARQLCRMKIQVAAGSIFSASGKYRNCLRTNCALPL
                     SETYREALKQIGEAVYRAME"
     gene            complement(37258..38214)
                     /locus_tag="ROH59_002081"
     CDS             complement(37258..38214)
                     /locus_tag="ROH59_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001678496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDX4804561.1"
                     /translation="MTNFTTSTPHDALFKSFLTHPDTARDFMEIHLPKDLRELCDLDS
                     LKLEYASFVDEKLRALHSDILWSVKTREGDGYIYVVIEHQSREDIHMAFRLMRYSMAV
                     MQRHIEHDKRRPLPLVIPMLFYHGSRSPYPWSLCWLDEFADPATARKLYTAAFPLVDV
                     TVVPDDEIVQHRRVALLELIQKHIRQRDLMGLIDQLAVLLVTGCANDSQITALLNYIL
                     LTGDEARFNEFISELIRRMPQHRERIMTIAERIHNDGWLLGRERGRKEGKEEGEKSLL
                     RLLLQNGADPEWIQRYTGLSAEQMQALDQPLPESKRDPWIEY"
     gene            38681..39913
                     /gene="mdtM"
                     /locus_tag="ROH59_002082"
     CDS             38681..39913
                     /gene="mdtM"
                     /locus_tag="ROH59_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HDX4804562.1"
                     /translation="MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
                     MHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFL
                     FGAATIALSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQVPVFGAVIVANTIVARFIK
                     DPTEPRFIWRAVPIQLAGLALLIVGNLLSPHVWQWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLA
                     GLLNRVRQHQAAELAEER"
     gene            39954..41234
                     /locus_tag="ROH59_002083"
     CDS             39954..41234
                     /locus_tag="ROH59_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HDX4804563.1"
                     /translation="MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDP
                     EMAARTDAVKSYLKEDEAFNRYLSELWGDLREWLKADINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHHVAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNF"
     gene            41350..42501
                     /locus_tag="ROH59_002084"
     CDS             41350..42501
                     /locus_tag="ROH59_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase subunit D"
                     /protein_id="HDX4804564.1"
                     /translation="MSLVTDLPAIFDQFSEARQKGFLTVMDLKERGIPLVGTYCTFMP
                     QEIPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEMLRLHKTVEERFGHE
                     ISEDALRDAIVLKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLDPRPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLQMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRHQHNIPYIAIETDYSTSDIGQLSTRVAAFIEML"
     gene            42511..43278
                     /locus_tag="ROH59_002085"
     CDS             42511..43278
                     /locus_tag="ROH59_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804565.1"
                     /translation="MAYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLAPATRAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSVEQLDSITENVIPHAITSMC
                     TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQRF
                     THMLESHLGMPVQTHPDAQFAGAIGAAVIGQRQRKRA"
     gene            43275..43532
                     /locus_tag="ROH59_002086"
     CDS             43275..43532
                     /locus_tag="ROH59_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDX4804566.1"
                     /translation="MKEYLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLC
                     IWLTCPPGEEIQWVIPGHTESVYCQQDGGWRCIAHYGISPR"
     gene            43597..44457
                     /locus_tag="ROH59_002087"
     CDS             43597..44457
                     /locus_tag="ROH59_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418753.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HDX4804567.1"
                     /translation="MTKSISLSKRIFVIVILFVIVAVCTFFVQSCARKSNHAASFQNY
                     HATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDLIRTIPLDFVKD
                     LETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQESPTNCGFEGLAYS
                     RQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDKALQRQFTLDDVSGAEFNQQKNTL
                     LVLSHESRALQEVTLAGEVIGEMSLTKGSRGLSHNIKQAEGVAMDASGNIYIVSEPNR
                     FYRFTPQSSH"
     gene            44525..45703
                     /locus_tag="ROH59_002088"
     CDS             44525..45703
                     /locus_tag="ROH59_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4804568.1"
                     /translation="MPSPSHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAE
                     GSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWL
                     LPFILVLLIRVLAGVASAGMLIFGSMLIMQHTRHPFVLAALFSGVGIGIALGNEYVLA
                     GLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPC
                     LTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLGNGTSALAGATLCGAAALFIAALISTVQLFKLQVVTS
                     "
     gene            complement(45716..46270)
                     /gene="kptA"
                     /locus_tag="ROH59_002089"
     CDS             complement(45716..46270)
                     /gene="kptA"
                     /locus_tag="ROH59_002089"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HDX4804569.1"
                     /translation="MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKVGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GLPFWQAENGVWLTSTVAVEFLEW"
     gene            46520..47203
                     /locus_tag="ROH59_002090"
     CDS             46520..47203
                     /locus_tag="ROH59_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804570.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            47200..47661
                     /locus_tag="ROH59_002091"
     CDS             47200..47661
                     /locus_tag="ROH59_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDX4804571.1"
                     /translation="MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            47674..48846
                     /gene="iadA"
                     /locus_tag="ROH59_002092"
     CDS             47674..48846
                     /gene="iadA"
                     /locus_tag="ROH59_002092"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDX4804572.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPS
                     DIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPVYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLSGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            48911..49822
                     /gene="hypT"
                     /locus_tag="ROH59_002093"
                     /gene_synonym="qseD"
     CDS             48911..49822
                     /gene="hypT"
                     /locus_tag="ROH59_002093"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HDX4804573.1"
                     /translation="MDDCGAVLHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGQLVVLNRDELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(49815..50207)
                     /gene="iraD"
                     /locus_tag="ROH59_002094"
     CDS             complement(49815..50207)
                     /gene="iraD"
                     /locus_tag="ROH59_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418746.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HDX4804574.1"
                     /translation="MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIM
                     LYHDDESLTFDLVWDNGGWRSATLENVS"
     gene            complement(50204..50287)
                     /gene="idlP"
                     /locus_tag="ROH59_002095"
     CDS             complement(50204..50287)
                     /gene="idlP"
                     /locus_tag="ROH59_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide IdlP"
                     /protein_id="HDX4804575.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
BASE COUNT        12319 a        12964 c        12551 g        12680 t
ORIGIN      
        1 caagcgtcgc atcaggcatt atgcgccgac tgccggatgc tgcctacgaa gggtaaacta
       61 cccactaacg ctaaacaacg catacgtatt attaagcaac acttcggcaa tctcatcttc
      121 tggttccggg cgcaactcgc aaagcacgtc aaacacccgc acagcctgtt ccggtcggtt
      181 aggctgcccc tgaaagccgt tgagcggcat atccggcgcg tcggtttcca gcaacaacga
      241 tgccagcggt aattttgcga tgacatcgcg ggttttactg gcgcgtggat aggtgatagt
      301 accgcctacg ccgattttgt agcccagctg tacaaaccgc tcggcctgtt gcaggctgcc
      361 ggaaaaaccg tgaaccacgc cagtgcacgg taaatcgtga cgtttaagat gcatcgccag
      421 tttgtcgtgt gtacgccggg aatgaaggat caccggcaga tcgtagcgtt tcgccagttt
      481 cagctgttcg tcgagtaacc actgctgcct ctcaaattgc ggatcgtcgc cgaagagatc
      541 cagaccgatc tcccccaccg ccaccacctt cgccggacgc ctttccagcg cctgctgtag
      601 ctgatcaaga gacacatcgc tatgtttttc caacatcccc ggatgcaacc ccaatgcggc
      661 atacagcggt tgatattttt ccgctaacgc ctgcacgcgg gcaaaatttt ccgcctctgt
      721 cgccggaaca atgatcttgc ctacgcccgc ttgtgccgcg cgttgcaggc tggcctcttc
      781 atcgccacta aacggcggga aatcaaaatg gcagtgggta tcgataaaac ggcaaatcaa
      841 gccagatcct cattgttaaa tgtcgggtcg ttcgcctgcg gagcatcgct cacttcggca
      901 accagcgtat cgttggcgac tggcgcaggc ggaataacga tcgattccgg cgtcaccact
      961 ggcaccagat ggcaggtaag cggcgctttt tcagttaata gcttgccaac cgtggcgagg
     1021 aaataacgac cgcataaacg cccaagttta tagtcttcac gcagcgccgg aatccgactg
     1081 ccaagcgcga tactatgtaa tggcttcggt ggataaattt cgaatatccg cagcttgccc
     1141 ggtggtttct caataaattg ctgaatgtca cgatagctgg tttcatgatg ctgcaccaga
     1201 ttgaccagcg gctgcaggct actgtcaccc agccagcgtt ccatgcgttt gaaccactgc
     1261 ggcgtgtagt acatttgtga cggcacagtg cggatgacga ccaacgtttt agcgccctgc
     1321 cttgccgcct ctttaaccgg aatcgcatca ctgatcccgc catccaggta gttaatgcct
     1381 tccagcgaca ctccgctacg ataaaagcca ggtatcgcac tggaggcgcg aatcacatcc
     1441 agccagtttt gtttggttgg taaaaagtaa ttaggcgcgt agtcatcctg acgacaggcg
     1501 cacatataaa acgatttgcc gctgtcaaac aaccgcgcgg cggtatccat ttgcaacggc
     1561 atctggcttg cggtggcctc caccagccag tcgagatcga taagatttcc tccacggaca
     1621 aagcgcaatg gatcgaaaaa ttcgcgtttt gtggtatagc gcatgatgac tttgcgcgcg
     1681 taaccgggct gattgcagat aaacgccgag aggttctgcg ccccggcaga tgtgccgaga
     1741 taaagatcga aaggattaaa ctgcgcgcgc ataaactcat ccagcacgcc agccgtgaaa
     1801 attccacgct gtccgccgcc ttcgcacacc agagctattc gtccaggctg gaacggcctt
     1861 agcgacaacg gcgcaatatt accaagcgtt acaggtattc gctgccccac ctctgccttc
     1921 ctgtttttgt tgtgaaagaa tgacaaagta acgcaattta ttattcgcta aaaccgcaaa
     1981 agccagtccg ctggactggc tttggataaa attttcttaa tgatctgaaa tctagggtcg
     2041 ttttcggccc atgaacaaac tcaccaggaa cagaataatc ccgacgacaa agacaatttt
     2101 agctgcgcct gcagcggtac cggccagacc accaaaccca agtgcggcgg cgattaacgc
     2161 gataaccaga aatatgatgc cccaacgaaa cataagcgtc tcctttacca tagttaatgt
     2221 caccgcttga tatgagcgtg aaaatcactc aatgcgatat ttttagtgtg gtgcacatcg
     2281 cgcctcccga caaagttcgg gaggacgaat tacgacgaat tacttagttt tcagatcatt
     2341 tttaacgctt ttcacaccat ctaccgcttt ggcgatactt tcagcacggt cgctctgtgc
     2401 ctgggaatcg acggtaccgg agagctgaac cacgccgtcg gtggtttcaa ctttcacatg
     2461 acgggaaggg acgatatcgt ccgccagcag tttggctttg atttcactgg tggtggcggt
     2521 gtcacccgcg tagcccttca cagagccttc tttagcgtcg cgaacgtgca gtttgtcgct
     2581 gacagaggtc accccttcaa cgcctttcgc cactttcact gcctcttcgg cctgagcctg
     2641 gctttcaacg aaaccgctca gggtcacgac tttttgatcg gttttgacag agatatcggt
     2701 gctcttgatg ttgtcatgat ccaccagggc cgccttcact ttcgcggtga tggcgctgtc
     2761 atccatgaaa ttaccgactt tattcataga gctatcgact ttttgccctg cgctttcatt
     2821 ggtagtctgc gcgttgtttt ccgcgtaggc agagcctgtc gcgacggcag aggtcaacat
     2881 tacagccagc agagttttcg aaatcttcag tcttgtcata gtcatcgatt tattcctgta
     2941 agtttgctcg taatttgagc ctggcaacac gaggttgcat tgctgaatag ggagagactt
     3001 caccctctac agaagtcaat ggtcgccatc acaaaagcga tgggtgatga ataacgacca
     3061 ttacagcctc tgaatcagtt attaatatcg gtagaatgac aatctacggc tttagatact
     3121 gatatctacg cattgaacgg tatttaacgc cgtcagaaat gtcattactt tgttaaatat
     3181 agatcacaat tttgaaaccg ctcggaatat catcgaaaac ataagcaaaa gtgaatgttt
     3241 taagaacatt ccgtaagcgg ctaataagga agggaaattg acagggcgca gcggctaccg
     3301 cgccctggag gcaagaatta atgctcgcgg gtctggtgga actgaacgtc cggataacgt
     3361 tcctgcgcca ggcgcaggtt gaccatgctg gtagcgatgt aagcgaggtt atcgccgcca
     3421 tcaagcgcca gttggctttc gttcttacgc ttgaactctt cgaatttctt cgcgtctgca
     3481 cattctaccc agcgggcggt ggcaacgttg actgattcat atactgcttc aacgttgtat
     3541 tcgctcttca ggcgcgatac caccacatca aactgcagca caccaaccgc accaacgatc
     3601 agatcgttgt tggagattgg acggaacacc tgcaccgcgc cctcttcgga aagctgtacc
     3661 agccctttga gcagctgttt ttgcttcagc ggatctttca ggcggatgcg acggaacagt
     3721 tctggcgcga agttcggaat accggtgaac ttcatcatct caccctgggt aaaggtgtcg
     3781 ccaatctgaa tggtgccgtg gttgtgcagg ccgaggatat cgcccggata tgcttcttca
     3841 acgtgcgaac ggtcacctgc cataaaggtc agcgcgtcgg agatcaccac atctttcgca
     3901 gtgcgcacct ggcgcagctt catgcctttt tcatatttac cggataccac gcgcataaac
     3961 gccacgcggt cgcggtgttt cgggtccatg ttggcctgaa ttttaaatac gaagccggta
     4021 aatttgtctt cgctcgcctc tacggtacgg gtatcagtct gacgcggcat cggcgcagga
     4081 gcccactcca ccaggccatc cagcatatga tcgacaccga agttacccag cgcagtaccg
     4141 aagaataccg gagtgatttc gcccgcaagg aacagctctt tgtcgaactc attagacgcg
     4201 cctttcacca gttccagttc gtcacgcagc tgctgtgcca gatcttcacc gaccgctgca
     4261 tcgagatccg ggttattcag ccctttaaca atgcggactt cctgaatggt gtggccttta
     4321 ccgctctgat agagataggt ttcgtcttta taaaggtggt aaacgccttt aaacagcttg
     4381 ccgcagccga tcggccaggt gatcggtgcg cagccgattt tcagctcgtt ctcaacttca
     4441 tcgagcagtt ccatcgggtc gcggatatca cggtcaagtt tgttcataaa ggtgaggatc
     4501 ggcgtgtcgc gcagacgggt aacttccatc agcttgcggg tacgatcttc aacacctttt
     4561 gcggcgtcga taaccatcag acagcagtcc accgccgtca gggtacgata ggtatcttcc
     4621 gagaagtctt cgtgccccgg ggtgtcgagc aggttaacca ggcaatcgtg atacggaaac
     4681 tgcatcacag acgtagtaat ggagatccca cgctgctttt ccatctccat ccagtccgac
     4741 ttagcgtgct ggttggaacc acggcctttt actgtaccgg cggtctgaat ggcctgtccg
     4801 aacagcagca ccttctcggt gatggtagtc ttaccggcgt ccgggtgaga aataatggca
     4861 aaagtgcggc gcttcgccac ctcttgcaaa taaggagaca acgtcataat tctttcttct
     4921 tgagtaagcg gcatcgcgcc gcgcttgttg aaaacgaaaa attgcggcta ttttacccat
     4981 caacgggggg gaggcaatca gtgtttacac aggagctgct ccagttcgtg caacgaagaa
     5041 acggtccagg tgggcgcgat gccttctggt tgctcgcgat ggtgcgcatt cagccagcag
     5101 gtcgcaagcc cggcgttgat gccaccgaga atatcggact cggcagtgtc gccaaccatc
     5161 agcacgcgtg aacggtcagg attgcccgcc tgttccagcg cataatcgaa aattttctta
     5221 ttcggtttgg caacgccaac ttcttcggaa atcaccagca aatcgaagta atcacgcagg
     5281 cccgtgcgtt ccagacgcac ttgctgcaag gcgctaaagc cgttggtgat gatgccgatt
     5341 ttagcgttgc cacgaatggc gttaagcagg gaaaccgccc ccggcaacgg cgtacagatt
     5401 tccgccatcg cattaataaa ggcctcgttg agtttacccg gttcgacgtt cagccgttcg
     5461 gcccagctct caaaccgccc gtgctgaagc tgtaatgaag tgatcacgcc gttttgataa
     5521 tccacccaca gtggcttgtt aacggcctga tagtcctgaa aatcttcagc ggtaaaggtg
     5581 acgctgtaat caagaaacat ccgctgcagg ccggtgaatg agtcaaaggt aaacagcgtt
     5641 tcatcggcat caaagaaaat ccagtcccac ttcattattc caccttgtct tacatactga
     5701 ttggtaacgc catgatgatg gcgtcttcgc gaccgtccgt ggtggggtag taattgcggc
     5761 gaatcgtcgc ctcgttaaag cctaaacttt cgtacagggc aatggcggca gcatttgagg
     5821 cacggacttc cagccatagc gtcgccacgc cgcgtttttc cagttcgtcg atcagatgtt
     5881 ccagcagcgc ccttcccagt ccctgacgct gatagtcagg atcgaccgca atattgaaca
     5941 atgtagcttc atccagcacc acttgcgtaa tcgcaaacgc cgccattttg ccgttttgcg
     6001 ttaactgaaa gttgagatag cgctcgccct ggttgctggc aaaggttttt tcactccacg
     6061 gaaaggtgtg ggcgcgttgt tcaatgtgga aagccgctgg taaatcagtc gtttcgaggg
     6121 aagaaatcgt gttcatatgt gcaaatttgt tgccataacg cggcgcgtgc cgttgggttt
     6181 gcccgtaatt cggtgagcgc cggtgatgtc acctgagcgc cttccagtga tagcggttcg
     6241 tcagtaccca accgccagct gttgcagcgg ctgccttgcg gcagcatcgc gattttttct
     6301 ggcgtcagtt gcagcacttg atcggggctg acggttaacg cacgcagaac atcgctcacc
     6361 agaggatcgg tcagggcggg aagatcgttt gccaccatca ccagacggac gtgtggcggg
     6421 atcgcaatgg caatctcccc ctgcaacgcg ccagggcgac gcagcgacca ctgggtaatg
     6481 cccagttgct gtaactgcca gtctcgtcgg gatgtcatag cgaatcgctc ctgttgtcag
     6541 gggcgcaaat atagcaaatt cgtcgatacc gcgccaacat atggctataa tcgccgccag
     6601 tatcaattga ggagcattcc atgtctgcat ttaccccggc aagtgaagtc ttgctgcgtc
     6661 acagtgatga tttcgaacaa agccgtattc tgtttgccgg agacttacag gatgacctgc
     6721 ccgcgcgttt agataccgcg gccagccgtg ctcataccca gcaattccac cactggcagg
     6781 tgttaaaccg ccagatgggg gataacgccc gttttagcct ggtcgccacg gcggatgatg
     6841 tcgctgattg cgatactttg atttactact ggccgaagaa taaaccggaa gcccagttcc
     6901 agttgatgaa tttactttct ctgcttccgg tgggcacgga tatttttgtc gttggcgaga
     6961 accgcagcgg cgtgcgcagc gccgagcaga tgctggccga ttatgcgccg ttgaataagg
     7021 tagacagcgc ccgtcgctgc ggcctctatt ttggtcgtct ggaaaagcag ccggtatttg
     7081 atgccaataa attctggggc gaatacagcg tcgatggctt gacggtcaaa acgctgccgg
     7141 gcgtgtttag ccgcgacggt ctggatgtcg gcagtcagtt gttgctctcg acgctaaccc
     7201 cgcacacgaa aggtaaagtg ctggatgtcg gctgcggcgc aggcgttctt tccgttgctt
     7261 ttgcgcgcca ttcaccgaag atccgcctca ctctgtgtga tgtttctgca ccagcggtag
     7321 aagccagtcg cgcaacactt gctgccaaca gtgttgaagg tgaagtcttt gccagcaacg
     7381 tcttttccga ggtgaaaggt cgttttgata tgatcatctc caacccgccg ttccacgatg
     7441 ggatgcaaac cagcctggat gcggcgcaaa cgctgattcg cggcgcggtg cgtcatctta
     7501 atagcggcgg cgagctgcga attgtagcga acgccttcct gccttacccg gacgtgctgg
     7561 atgagacatt tggtttccac gaagtgattg cgcaaaccgg gcgcttcaag gtgtatcgcg
     7621 ccattatgac ccgccaggcg aagaaaggtt aagtatctga tatctgtcgc cgcataccgt
     7681 gttggatgcg gcgtacacgc cttatctgac cgacaaacga attatccaca atccgctgat
     7741 ggacattttt ccagcaatta cacctctgtc gataattaac tattgacgaa aagctgaaaa
     7801 ccactagaat gcgcctccgt ggtagcaatt ctttttaaga attgatggta tgcgaaggtg
     7861 gcggaattgg tagacgcgct agcttcaggt gttagtgtcc ttacggacgt gggggttcaa
     7921 gtcccccccc tcgcaccaaa aaccacgttg atattgctcg cactgggcga aggtggcgga
     7981 attggtagac gcgctagctt caggtgttag tgttcttacg gacgtggggg ttcaagtccc
     8041 ccccctcgca ccaaacgagg caatatcaaa aaaagtaaga tgactgtgcg aaggtggcgg
     8101 aattggtaga cgcgctagct tcaggtgtta gtgtccttac ggacgtgggg gttcaagtcc
     8161 cccccctcgc accaattatc tttacttctt ttcttgtctc ttcactgttt tatcacccct
     8221 gattcaaatt cattatcatc agcatgatgc cagcaataag cgccaggcac gatggtagca
     8281 aaacgtaatg ccgtaactgt ttgtgataca gcatcaccgg cgtcaatacc aatcccatca
     8341 gaatgacaat ccgccattga tccggcgata aatccgcata catcagccct gtaatcagca
     8401 atcccggcag caacactccc cagccactgc ccagcgtacg ttgcaacatg gtttcatctc
     8461 tttcattgat aatgataacc aatatcatat gataattttt atcatttgca agccagagaa
     8521 atcccttgct atcggataaa cctatcgcta ggattagcaa tcattatcat ttagattact
     8581 atcccgatta tggcctatcg ttccgcaccg ctctatgaag atgttatctg gcgaacgcat
     8641 ctccagccac aggatgctgg gcttgcacaa gccgtacgtg cgacgatcgc caaacatcgt
     8701 gaacatttgc tcgagtttat ccgcctggat gaacccgctc cgcttaacgc catgacgctg
     8761 gcgcaatggt catcaccgaa tgcgctaagt tctctactcg cggtctattc cgatcatatc
     8821 tatcgcaacc aaccaacgat gatccgcgag aacaaaccgc tgatctcact atgggcacaa
     8881 tggtatatcg gcctgatggt gccaccatta atgctggcgc tactgacgca ggaaaaagca
     8941 ttagatgtgt cgccggaaca tttccatgct gagtttcacg aaaccggccg tgccgcctgt
     9001 ttctgggtcg atgtgtgtga cgataaaaac gcaacaccac attcgccgca gcagcgaatg
     9061 gaaacgttaa tcagccaggc gctggttccg gttgtgcagg cactagaagc gaccggagag
     9121 atcaacggca aacttatctg gagtaatacc ggttatttga tcaactggta tctcactgag
     9181 atgaagcaac tgctcggcga ggcgacggtt gaatcgctgc gccatgccat cttttttgag
     9241 aaaacgctca cgaacggtga agataatcca ctctggcgta ccgtggtact gcgcgacggc
     9301 ctgctggtgc gccgcacttg ctgccagcgt tatcgcttac cggatgtgca gcaatgtggc
     9361 gattgtacgc tgaaatgaaa gcactgccgg ggaagtaaac ccggcatcat gcggattaat
     9421 agggatgcaa cacattactt gcttcgcaat gccgcataca taacagaata tctgcggcct
     9481 ccaacaatcc tgcatcagaa ctgacgccca gtttcgacat cacattaaat ttatgcgcgc
     9541 ggatcgtttt gatattgcgt ttaagctgct cggcaatttg tgtcattgag tagccacgcg
     9601 acataaagcg caatatttct ctctccgtcg ggcttagcgt ccggctttgg ttaatgtacc
     9661 actgattgtt cagtcggtcg gtcgcctgac gtacaccatt taatgacaaa aagagttcct
     9721 gatgaaaaat ctccagcgtt gacgctttac ttaatacacc gtccagcggt gatggcgaca
     9781 atgaaccaat cagccgagct tcaatatcat catccgcaat aactaaacgc cgggtacgcg
     9841 gaaacttaat cgccagttca gtcaggcaag ataatccctc tctgcgctca cttctcatgg
     9901 cagaaaaaga aaaaatgacc gccgcaaacg agatccgcga catggcatcc tgaaatgact
     9961 cctgactggt ataggtatgg agcttataag ggttgcccgc aaactttctg aataaactct
    10021 caataccgat actactcatg acgcattttt ctatgagtgc gacatttctc ttcttaattc
    10081 ggctgtgttc cattctgcgg catctccata aacagaaggc aagttaagtt ctcttgcacc
    10141 ctgcgcgcta tttatccatg catacatttc agcgttgctg tgaattgcca gtcgacgcat
    10201 cgcactgttt ttttgggcgc tgatagtttt attacttttc ttaagcaatg aagctatctg
    10261 gttgatgccc catcctttac ctaatagccg cagtaccttg cgctctgaaa gagtgagaat
    10321 gacggagcga tagctaaaat catgagtttc agtcattgcc ggagaggtca gcatggcgct
    10381 gatacgctct gcgtgcgtat tgccggaacg tacggtcttg accagattct caatgggttc
    10441 aacatcagac aataacgtcg ccgtagggca catgagcagt tctactgcct gggaatacca
    10501 ggagcgtgac accatgaaaa cccagtgaat ttcccgatat tgtgagatta aagaataata
    10561 atgttcacaa acagaacgtg gatcttcact ttcaccggct aaatcagcaa tgactaatcc
    10621 ggaacgacgt aattgtaata aggtaaggtc ctccgcagag gcgctggata ttatttcata
    10681 ttcagggaag tgagtcctca tgacctcttt taaccctgct tgcataacag gtattttact
    10741 gataacaatt ccatttttgc agcatcctgg caacatattt cctccacatc cactgtctaa
    10801 aaattatgat ggtttattca ggatattcat tccttaaatg tttccagcaa attaatagat
    10861 taagcgaata aattatcctt agcattcact ttcatatcag catactcctg ctgcacaaca
    10921 actccactgc atgtgtcaga aggttagcat caaatgataa cctggtgaaa tagcctggag
    10981 acatttaaaa tatctacatt aagttgttag gaatacttaa tgaaaaacag aaatcacatt
    11041 catttaatta taaattaaat gatatccctt cccgcagaat gcgggaatca cacaatcaat
    11101 atttattcaa taaaatctga tgattttaac ttgttaacac taaaaaacgc gcccagctat
    11161 ctattatcct gacccgtaaa ggctaaaaca ataaattcat tatagtgata atattcatgt
    11221 gatagtttgt ttgcggcgag agataattcg ctttttatca ccgagcttgt cccgataacc
    11281 aggattaatc agcgcaattt tgatcttaac ctacctcaaa acaaccgtgc ttcatgatac
    11341 aaatggattc tcattatctg aacaatacgc agcacgtcta tgacaaaggg cgagttatgc
    11401 aaactgagca acagcgagcc gtaacgcggc tttgtatcca gtgtggatta tttcttttgc
    11461 aacatggtgc ggaaagcgcg ttggttgatg agctttcctc acgactgggt cgggcgttgg
    11521 gaatggacag cgtcgaaagt tctatctctt cgaacgccat agtgctgaca actattaaag
    11581 atgggcaatg cctgacatcg acacgaaaaa atcacgatcg cggcattaat atgcatgtgg
    11641 tgactgaagt ccagcacatt gtgattcttg cggagcatca tctgctggat tacaaaggcg
    11701 tagagaaacg atttagccaa attcagccat tacgttaccc aagatggctg gtagccttaa
    11761 tggttggcct ttcttgcgcc tgtttctgta aactcaataa cggtggctgg gatggtgccg
    11821 tcatcacctt ctttgccagt acgaccgcga tgtatatccg ccagctgctg gcacaacgtc
    11881 atcttcatcc acagatcaac ttttgcctta ccgctttcgc cgccaccacc atttccggat
    11941 tgcttttgca actccccact ttcagcgata cacccaccat tgcgatggcc gccagcgttc
    12001 tgctgctggt gccgggcttt ccgttgatta atgccgtcgc cgatatgttt aaaggccaca
    12061 tcaataccgg actggcacgc tgggcgatcg ccagtctgct gacgctggct acctgcgtcg
    12121 gcgtggtgat ggcactgacg atttgggggc tacgcggatg ggtgtgatcg agtttctgtt
    12181 tgcattggcg caggatatga tcctcgccgc cattccagcg gtcggctttg cgatggtgtt
    12241 caacgttccc gtgcgggcgt tacgctggtg tgcgctgctt ggcgcgattg gccatggttc
    12301 acgaatgatc ttaatgacca gcgggctgaa tattgagtgg tcaactttta tggcttctat
    12361 gctggtcggc accattggta ttcaatggtc gcgctggtat ctggcgcatc cgaaagtgtt
    12421 taccgtggcg gccgttatcc ctatgttccc gggcatatcg gcttataccg caatgatttc
    12481 ggcggtaaaa atcagccagt taggttacag cgaaccgttg atgattaccc tgttaaccaa
    12541 ctttcttaca gcttcatcga ttgttggtgc gttatccatc ggtctttcca ttcctggatt
    12601 atggttgtac cgcaagcgcc ctcgcgtata aaattgcctc gcttaagcac acggatgaga
    12661 gacagcctcc tctcctccgt gtgttactat aaaagttatc tcccttctcg ttcatcgttc
    12721 catatttgag aaacagtatg tcttccagag ttttgacccc ggacgtcgtt ggtattgacg
    12781 ccctggtaca cgatcaccaa accgttctgg caaaagctga aggcggtgtg gttgccgtat
    12841 ttgctaacaa tgccccggcg ttttatgccg tcacgcctgc acgcctggct gaactgctgg
    12901 cgctggaaga aaagctggcg cgtccgggaa gcgatgtcgc tctggacgat caactctatc
    12961 aggaaccgca agccgctccc gttgctgtcc ccatggggaa attcgccatg tatccggact
    13021 ggcaacccga tgccgacttt atccgcctgg cggcgctatg gggcgtggcg ctaagagagc
    13081 cggtgaccac cgaagaactg gcctcattca ttgcctactg gcaggcggaa ggtaaagtct
    13141 ttcaccatgt gcagtggcaa caaaaactgg cgcgcagcct gcaaatcggt cgtgccagca
    13201 acggcggact gccgaaacga gatgtgaata cggtcagcga acctgacagc caaattccac
    13261 caggattcag agggtaacga tgaaaaacgt tggcgacctg atgcaacgcc tgcaaaaaat
    13321 gatgcctgcc catatcaaac ctgcattcaa aacgggtgaa gagctactgg cctggcagaa
    13381 agaacaaggg gcgatccgct ccgccgctct cgaacgtgaa aatcgggcga tgaaaatgca
    13441 gcgcaccttt aaccgctccg gtattcgtcc actgcatcag aactgctcct ttgagaacta
    13501 tcgcgttgag tgtgaagggc agatgaatgc gttaagcaaa gcgcgccagt atgtcgaaga
    13561 gtttgacggc aacatcgcca gcttcatctt ttctggtaag ccaggaaccg gcaaaaacca
    13621 tctggcggcg gcaatctgca acgagctgct gctacgcggt aaatccgtat tgatcatcac
    13681 cgtggccgat attatgtcgg cgatgaaaga taccttcagg aatagcggta ccagcgaaga
    13741 acaactgctt aacgatctga gcaacgttga tctgctggtg atcgatgaga tcggcgtgca
    13801 gaccgaatcg aaatacgaaa aagtgatcat caaccagatc gtcgatcgcc gctcttcttc
    13861 caaacgccca accgggatgc tgaccaacag taatatggaa gagatgacca agttgctggg
    13921 cgaacgcgtg atggaccgta tgcgcctggg taacagtttg tgggtgatct tcaactggga
    13981 tagctaccgt agccgtgtaa caggtaaaga gtattaatcc ccgtttctgg cggtatactg
    14041 cgacacaatt ccaccttgag taatgatgat gaaaactgtt aaacatcttc tgtgctgtgc
    14101 cattgccgcc agcgcattaa tttccaccgg ggtgcatgct gcgtcctgga aagatgcgct
    14161 ctccagcgcc gccagcgaac ttggcaacca aaacagcacg acacaggaag gcggttggtc
    14221 gctcgcgtca ttaactaact tgcttagcag cgggaaccag gccttaagcg cagataacat
    14281 gaacaacgcc gcaggcattc tgcaatactg cgcgaagcaa aagctggctt cggtaaccga
    14341 tgccgaaaac atcaagaacc aggtgctgga aaagctgggc ctgaacagtg aagagcaaaa
    14401 agaagacacc aactatctgg atggcattca gggtttgctg aaaaccaaag atggtcagca
    14461 actcaatctg gataacatcg gaacgactcc gctggcagaa aaggtgaaaa ccaaagcctg
    14521 cgatctggtg ttaaagcagg ggctgaactt catttcctga accgcgaaac gccgcgtttt
    14581 agctgttacc cggctgacgc ggctctctcc tgcccttttc cctgctcctg gacggtttta
    14641 cccctgttac acgggaagcg atcgcgatca aaaaagtctg tttataaact aattcctaac
    14701 aacatcgcat ttttttgaca ctagaattgc agcaatatgg cgacgccatt acattgtgct
    14761 tctcaaaaag cttaaacgtt ggctaaacgg cccggtttag tgaggatcgc ccgttgtcag
    14821 aactactctc tttcgccctt tttctcgcct ctgtgctgat ttacgcatgg aaagcgggac
    14881 gtaacacctg gtggtttgca gccacattaa cagtgctggg gctatttgtc gttttaaata
    14941 tcaccctgtt tgccagcgac tattttactg gcgatggtat taacgacgcg gttctctata
    15001 ccttaaccaa cagcctgacc ggtgctggcg tcagcaaata catcctgccg ggtatcggca
    15061 ttgtgctggg gctgacagcg gtgttcggtg cgctgggctg gatcctgcgc cgtcgtcgcc
    15121 atcatccgca ccattttggt tacagcctgc tggcgctctt actggcgctg ggttcggtgg
    15181 acgccagccc ggcatttcgt cagataacgg aactggtgaa atcccagtca cgcgatggcg
    15241 acccggactt tgcggcttat tataaagagc cgtcgaaaac tatccctgac ccgaaactca
    15301 acctggttta tatctatggc gaaagtctcg agcgaaccta ttttgataac gaggctttcc
    15361 cggatctcac gcctgaactg ggcgcgttga aaaatgaagg cctggatttc agccacacgc
    15421 agcagctgcc aggaacggat tacacgattg cgggcatggt ggcttctcag tgcggcatac
    15481 cgctgtttgc cccctttgaa ggcaacgcct ccgcctctgt ctccagcttc ttcccgcaga
    15541 acatctgtct gggcgatatc ctgaaaaact cgggttatca gaactatttc gtgcagggcg
    15601 caaatctgcg ttttgccggt aaagatgtgt tcctgaaatc gcacggcttc gaccacttat
    15661 acggctcaga agagctgaaa agcgtggtag ccgacccgca ctatcgcaac gactggggat
    15721 tctacgacga taccgttctc gatgaagcgt ggaaaaagtt tgaagagctt tcccgctcag
    15781 gtcagcgatt ctcactgttt accctgacag tcgataccca tcacccggat ggttttattt
    15841 ctcgtacctg taaccgcaaa aaatatgatt ttgacggtaa accgaatcag tcattcagcg
    15901 cggtaagttg cagccaggag aatatcgcga cgtttatcaa caaaatcaaa gcgtcaccgt
    15961 ggtttaaaga tactgtcatc gtcgtctctt ctgaccattt agcgatgaac aacacggcgt
    16021 ggaaatacct caataagcag gatcgcaata acctgttttt tgtcattcgt ggcgacaagc
    16081 cgcagcaaga gacgctggca gtgaagcgta acacgatgga taacggcgcg acggtgctgg
    16141 acattctcgg tggcgataac tatctcggac ttggtcgtag cagtttatcc gggcagtcga
    16201 tgtcggaaat cttcctcaat atcaaagaga aaacattgac gtggaagcca gatatcatcc
    16261 gcctgtggaa attccctaaa gagatgaaag agttcaccat cgaccagcag aaaaacatga
    16321 ttgccttctc gggtagccat ttccgtttgc cgctgctgtt gcgggtttca gacaaacgcg
    16381 tggaaccgct gccggaaagc gaatactcag caccgctgcg tttccagctg gccgatttcg
    16441 ctccacgcga caatttcgtc tgggttgacc gttgctataa gatggcacaa ctctgggctc
    16501 cggaactggc actttccacc gactggtgtg tctcgcaggg gcagcttggc ggtcagcaaa
    16561 ttgtccagca tgttgacaaa acaacatgga agagcaagac ggcatttaaa gatacggtca
    16621 tcgacatggc gcgttacaaa ggcaatgtcg atacgctgaa gattgttgat aacgatattc
    16681 gctacaaagc cgacagtttc atctttaacg tcgccggtgc gccagaagag gtgaaacagt
    16741 ttagcgggat ttcccgtccg gagtcgtggg gccgctggtc caacgcgcag ctgggcgatg
    16801 aagtaaaaat cgagtacaag catccgctgc cgaagaaatt tgacctggtg attaccgcca
    16861 aagcatacgg caataacgcc agccgtccta ttccggtacg cgtaggcaat gaagaacaaa
    16921 ctcttgtgct gggcaatgaa gtgaccacca ccacactgca tttcgataac ccaaccgatg
    16981 ccgacacact ggtaattgtg ccgccggaac ctgtctcaac caacgaaggg aatatcctcg
    17041 gacactcgcc gcgtaagctc gggatcggca tggtggaaat taaagttgtg gaacgtgaag
    17101 ggtaattcct gactgatgtg taggtcgcat aaggtgcgac ctacacacct tctccggcct
    17161 acaaaacatc attgagaaac agaaaaaaaa cagcgcccaa cacttccccg gacgctgcat
    17221 ggcaacttta ataatctcgc cttatcagaa agtaattacg cctttaatta actcacgatt
    17281 gttaatcaca tcgcgctcgt aggtttctgc cagcgtggcg aacggatagc gatgggttaa
    17341 catcatgtcg gcagtgattt tcccttccgc cataagtcga ccgactttag cgaaatcttc
    17401 cggcgtggcg ttgcggctgc ccatcatcgt cgtttctttt ttatggaatt ccggatcgga
    17461 gaactgcaac tcacctttaa acaggccgac aaataccacc gtgccaccgt gacgaatcag
    17521 attcacggtg ttattcatcg catgttgatt acctgtcgcg tcgatcactt tctgcgccag
    17581 cgaaccacca aactgcgccc gcagctgcgc gtcaaaatct tcggctgacg ggtccagcac
    17641 gggcaactcc agacgcgttg ccacatgttc acggcgcgcc ggactggtat ccgccaccac
    17701 cacctgtgcg ccatcggctt tagcgattgc cgccgcgccc agaccgattg gccccgctcc
    17761 gaccaccagc acctgctcgc cgggagcaat ggctgcgcga cgcaccgcat gagcgctaat
    17821 agcgaaaggt tcaatcaatg cggccgcctg cgggtcaata ccgtctgcgg gcaaaatgtt
    17881 cgccaccggc acgctcaaat actcactaaa accgccatcc tgatgcacgc caatgactga
    17941 aattttttca cagcaattgg tacgcccgct tttacacgcc gggcattgct gacaggcaac
    18001 ataagggatc acagcaactt gctgaccatt tttaagatca gcaacatttt tacccagccc
    18061 aacaacctcc ccacatattt catggcctaa aacccgtgga taactaaaaa atggttgatt
    18121 tccaccccag gcatgaatat cggtaccgca aatcccgaca gacttaattt ttattaatgc
    18181 ttcattgtca cccggaatag gaatctcgcg ttgtttccag actaattctt tcggctgctg
    18241 gcaaattaaa acattcatcg tagacatgat tcggctctcc attttttgtt gccttagata
    18301 tcaatgaaaa tgaaaaatgg cagcggaacg gaaaatctgt tttgtgaaaa cacgcgcata
    18361 aaaatgtttt aaatcgggtt ttaatggact cacaaggagg aaaatatgag tcgttcacaa
    18421 aatttacgcc acaatgtgat taaccaggtc attgatgata tggcgcgggg tcatatccct
    18481 tccccacttc catcgcaaag tgcgctggcg gaaatgtaca acatcagccg cactacagtg
    18541 cgtcatattc tcagccactt acgcgaatgc ggcgtcttaa cgcaggttgg aaacgactat
    18601 gttattgcgc gtaaacctga ccatgatgac ggtttcgcct gtactaccgc ttcaatgagt
    18661 gaacaaaaca aagtgtttga gcaggctttt ttcacgatga taaaccagcg ccagttacgc
    18721 ccaggggaaa ctttttctga actgcaactg gctcgggccg cgggtgtcag cccggtggtt
    18781 gtaagagaat atcttttaaa attcggccgt tataatctta ttcaaagcga aaagcgcggc
    18841 cagtggagca tgaagcaatt cgatcaatcc tacgccgagc agctgtttga gctacgcgaa
    18901 atgctcgaaa cacattcact tcagcacttt ctcaacctgc ctgatcatga tccccgctgg
    18961 ctgcaggcga aaaccatgct cgaacgtcac aggctactgc gtgacaacat cggcaatagc
    19021 tttcgcatgt tctcgcaact tgacagagat tttcactcct tactgctttc agctgccgac
    19081 aatatctttt ttgaacaatc gcttgagatc atatcagtca tctttcattt tcactatcaa
    19141 tgggacgaaa gcgatcttaa acagcgcaat atcattgccg tcgatgagca tatgaccatt
    19201 ctcagcgctc tgatttgccg cagtgacctt gatgccaccc ttgcgctccg taaccatttg
    19261 aattcagcta aacaatcaat gattcgatcc attaatgaga acatgcgtta tgctcattaa
    19321 gtacggatta aaaacagcaa actattagcg ggtgcacggt tttatcaaaa gataaatacc
    19381 ggaaaattcc cgcttaccta tgctcacaat cagtcgacta aaaatgtttt tttgtgagcg
    19441 gtagtaaagt cctaaaactt taacctgccg ttaatgtcaa ccttgcgtaa tgcacaatta
    19501 cgtaaacaat taaaattata aatacaggag tccggcgtgg aaaaagaaaa tatcaccctc
    19561 gatccgcgtt cttcatttac tccatcttcg tcggcagata ttcccgtgcc accagatgga
    19621 ttagttcaac gcagtacccg aattaaacgc attcaaacca ccgccatgtt gttattattt
    19681 tttgcggcgg taatcaatta tctcgaccgc agttcgctgt cggtagcaaa tttaacgatt
    19741 cgtgaagaat tgggattaag tgccaccgaa atcggcgctt tgctctccgt gttttcactc
    19801 gcttacggga ttgcgcaact tccttgcggc ccactattgg atcgtaaagg cccgcgcctg
    19861 atgttgggac tggggatgtt cttctggtca ctgttccagg caatgtctgg catggtgcac
    19921 agctttacgc agttcgtgtt ggtgcgtatc ggtatgggaa ttggtgaagc gccgatgaac
    19981 ccatgcggtg taaaagtcat taacgactgg ttcaacatca aagagcgcgg acgcccgatg
    20041 ggcttcttca acgcagcttc taccattggc gttgccgtaa gcccaccgat tctggcggcg
    20101 atgatgctgg tgatgggctg gcgcgggatg tttattacca ttggtgtact ggggattttt
    20161 ctcgccatcg gctggtatat gctctatcgc aaccgcgagc acgtagaact gactgccgtt
    20221 gaacaagctt atctcaatgc aggtagcgtc aatgcccgcc gagatccgct cagttttgcc
    20281 gaatggcgca gcttgttccg taaccgcaca atgtggggaa tgatgctcgg attcagtggc
    20341 atcaactaca ctgcgtggct gtatctggcc tggcttcctg gttacctgca aacagcctat
    20401 aacctggatt taaaaagcac agggttgatg gcggctatcc ctttcctgtt tggggctgcc
    20461 gggatgctgg tcaacggtta cgttactgac tggctggtca aagggggaat ggctccgatt
    20521 aaaagccgta agatctgcat tattgccggg atgttctgtt ctgccgcctt tacgctggtc
    20581 gtaccgcaag cgacaacatc catgacagcg gttctgctga ttggtatggc actgttctgt
    20641 attcactttg ccggaacatc ctgctggggc ttgatccacg tcgcagttgc ttctcgcatg
    20701 actgcgtcgg tgggcagtat ccagaacttt gccagcttca tctgcgcctc ttttgcgccg
    20761 atcattactg gttttattgt tgataccacc cactcattcc gtctggcact aatcatctgc
    20821 ggttgcgtca ccgcagcggg ggcactggcg tacatcttcc tggttcgtca gccgatcaac
    20881 gacccacgga aagattaatc tccctatgcc cgataacatt ttgcttatcg ggcattttta
    20941 tggcgattaa aacgtttccc agttctcacc gctatctgcc acggccattt tacgcggcgc
    21001 agctggcatc acggttttta ccacagccga tgtttcacgc tgctgttgct gctgttgctg
    21061 aatccggaac actgccactg cttcggtcag gcgactggcc tgctcttcca gcgcggcggc
    21121 ggcggcggca gattcttcca ccagcgcggc gttctgttga gttacccggt ccatctcagc
    21181 aaccgctaag ccaacctgat cgataccacg gctctgctca tcagaagcag aagcaatttc
    21241 gcccataatg tccgtcacgc gggtcacagc actgacaatc tccgccattg tttccccggc
    21301 gctttcgacc agcgtagagc caacatccac tttccccacc gagtcttcaa tcaggctttt
    21361 aatttcacga gccgcctggg cgctacgctg ggccagatta cgcacttctc ccgcaaccac
    21421 cgcaaaacca cgtccttgct cacccgcacg cgctgcttca accgccgcgt tcaaagccag
    21481 aatattggtc tggaaggcaa tgccgtcaat tacgctgata atatcggcga ttttctgcga
    21541 actggtggag atatcacgca tagtctgcac cacgttatct accactttgc cgccgcgttg
    21601 cgccgtttca gaagcactta acgccaggtg gctggcctgg cgcgcattct cggcgttctg
    21661 tttcaccgtt gcggtcagtt gctccatgct ggctgccgtc tcttccagcg aagcagcctg
    21721 ttgctcggtg cgcgaagaga gatcgttatt gccggtagcg atttcgctgg caccgctata
    21781 gatggcattg gccccgttgc gcacatcacc gacggtacgc atcagctctc cctgcatatg
    21841 gcgcaaactc tctgccagtt gccccatctc attagagcca tccacctcaa tcggtttcac
    21901 cagatcgccg cctgcaatat gacgaatgct gtcaatcagg cgattcattg gcgctaccag
    21961 cgaggcttta ataccgaacc agacggcgaa gatgaccgcc agtacgacga tcatcacgcc
    22021 caccagaatc cacatcgcct ggctgtagga ggcattgtta tcgctgacgg cgatatcatg
    22081 gagccgatcg ttttgttcca tgtaagccac atactgcttc tcgaaaccgt cctgatatcc
    22141 ctgagtcggc tgatcaaaga actcgttgat tttgcctgca cctaacagtt ggatcagctc
    22201 cgccagcgca ttgtgataaa tatcgtaatt acgtttgatc tctgccgctg cggcggtgct
    22261 ctgacgcggg tcacgcggca acgcttcgta atccgcccag tttttttccg cctgtttcag
    22321 cgaaatactg gcactctgca tcagctcagc aacggttgaa ccgctaccaa tattattctg
    22381 atccatcatg tagcggatac ccgcgcggtt gagggtgtta cgcgtctgca acaacgcgac
    22441 ccagctgcca ttcagcgtgg attgctgctg gcgaatggtt tgtaaaacag tgaaattttc
    22501 tttgtcattc tttaaggcat taaagaacag accgcctgat gtcagttgta aaaggccaaa
    22561 aacggccaaa accagcagta agctggtcac aattttgata cgttttaaca tggtttctct
    22621 ttcctgtgga ccgatgcaag attttcggcc tggaaaggaa aaactttatg aatatcccgc
    22681 ggagattacg ccgagtaatt ttattcacac tctgaattta aaaagccatt atttacataa
    22741 attattcaca atataaatat gtgatatgaa tcacatattt atcgtcactt aaacgacgcc
    22801 tttgccgctc aaccgcaaaa ctgaccgctt acatccctaa aataaccact cagttattta
    22861 ccttacttta cgcgcgcgta actctggcaa catcactaca ggatagcggt caatttatct
    22921 cctcaaacgc aacgcaaacc tagaacggct tcggccaact attaatcaat acatgccagg
    22981 ttttactatg gatactaaaa agatattcaa gcacataccc tgggtgattc tcggaatcat
    23041 cggtgcattc tgcctcgcgg tagttgcatt acgtcggggg gagcacgtca gcgccctgtg
    23101 gatcgtggtc gcctctgtat cggtgtatct ggtggcgtat cgctactaca gtctgtacat
    23161 cgcccagaag gtgatgaaac tcgaccccac gcgcgcgacg cctgcggtta ttaacaacga
    23221 cggtctgaac tacgttccga ccaaccgtta cgtgttgttt ggtcaccact tcgccgctat
    23281 cgccggtgct ggtccgctgg tgggtccggt tctcgccgcg cagatgggct acctgcctgg
    23341 cacgctgtgg ctgctggcgg gggtcgtgct ggccggtgcg gttcaggact ttatggtgct
    23401 gtttatctcc tctcgccgta atggcgcatc tcttggtgag atgatcaaag aagagatggg
    23461 accagtaccg gggactatcg cgctgtttgg ctgtttctta atcatgatca tcatcctcgc
    23521 cgtcctggcg ctgattgtgg ttaaagccct ggccgaaagt ccgtggggtg tcttcaccgt
    23581 ttgctcaacc gtaccgattg cgctgtttat gggtatctac atgcgcttta ttcgtccggg
    23641 gcgtgtgggt gaagtctctg tcattggtat cgtgctgctg gttgcctcta tctacttcgg
    23701 tggcgtgatt gctcacgatc cgtactgggg tccggcactg acctttaaag acaccaccat
    23761 taccttcgcg ctgattggct atgcgtttgt ttccgcactg ctgccggtgt ggctgatcct
    23821 cgcaccgcgc gactatctgg caaccttcct gaaaatcggc gttatcgtcg gcctggcgct
    23881 gggtatcgtg gtgctgaacc cggaactgaa aatgcctgcc atgacccagt acattgacgg
    23941 tactggcccg ctgtggaaag gcgctctgtt cccgttcctg ttcatcacca tcgcctgtgg
    24001 tgcggtatct ggcttccacg cgctgatctc ttccggtacg acgccaaaac tgctggctaa
    24061 tgaaaccgac gcgcgtttca tcggctacgg cgcaatgctg atggagtcct tcgtggcgat
    24121 tatggcgctg gttgctgcgt ccatcatcga accgggtctt tacttcgcga tgaacacccc
    24181 gcctgctggc cttggcatca ccatgcctaa cctgcatgaa atgggtggcg agaacgcgcc
    24241 gatcatcatg gcgcagctga aagacgttac cgcacacgcg gcagcgaccg tcagctcctg
    24301 gggcttcgtg atttcgccag agcagatcct gcaaaccgcg aaagacattg gtgagccttc
    24361 tgtcctgaac cgtgcaggtg gtgcgccgac gctggcggta ggtatcgctc acgtgttcca
    24421 caaagtgctg ccgatggctg acatgggctt ctggtatcac ttcggtattc tgttcgaagc
    24481 actgttcatc ctgaccgcgc tggatgcggg tacccgttct ggccgcttta tgctgcaaga
    24541 cctgctgggt aacttcatcc cgttcctgaa aaaaaccgac tctctggttg ccggtatcat
    24601 cggtactgcg ggctgtgtgg gtctgtgggg ctacctgctg tatcagggcg tggtcgatcc
    24661 gctgggcggc gttaagagcc tgtggccgct gttcggtatt tccaaccaga tgctggcagc
    24721 cgtagcgctg gtactgggca ccgttgtgct gattaagatg aagcgcaccc aatacatctg
    24781 ggtaactgtt gttccggctg tatggctgct tatctgcacc acctgggcgc tgggcctgaa
    24841 actgttcagc accaacccgc agatggaagg cttcttctac atggcaagcc agtacaaaga
    24901 gaagattgct aacggtactg acctgacggc gcagcagatt gccaacatga accacatcgt
    24961 tgtgaacaac tacaccaacg cgggcctgag tattctgttc ctgattgtgg tgtacagcat
    25021 catcttctac ggtttcaaaa cgtggcttgc ggtgcgtaac agcgacaaac gtactgacaa
    25081 agaaacaccg tacgttccaa tcccggaagg cggcgtgaag atctcttcgc accactaacc
    25141 gtgtttagcc ccgcttcggc ggggctttgt tcttatcaga gtgaactatg tttggtaact
    25201 taggacaggc aaaaaaatat ctcggccagg cggcgaagat gttgattggc attccagact
    25261 acgacaacta cgtcgagcat atgaagacca accatcccga caagccgtac atgagctatg
    25321 aagaattctt ccgcgaacgc cagaatgcgc gctacggcgg cgatggtaaa ggcggtatgc
    25381 gctgttgtta atggagagag catgaacccg attgcagtta ccctactcac cggtttttta
    25441 ggcgcaggca aaaccaccct gctgcgccat attcttaacg aacaacacgg ctacaagatt
    25501 gccgtgattg aaaacgaatt cggcgaagtc tccgttgatg atcaactgat tggcgaccgc
    25561 gccacgcaga tcaaaacgct gaccaacggc tgcatctgct gttcgcgctc caacgagctg
    25621 gaagacgcac tactcgacct gctggataat ctcgacaagg gcaatattca gttcgaccgt
    25681 ctggtcattg aatgcaccgg catggccgat cccggcccga ttattcagac ctttttctcc
    25741 catgagattt tatgccagcg ttacctgctg gacggcgtga ttgcgctggt ggatgcggta
    25801 catgccgatg agcagatgaa ccagttcacc atcgcccagt cacaagtggg ctacgccgac
    25861 cgtattctgc tgactaaaac cgacgtcgca ggcgaagcag aaaaactgcg tgaacgcctg
    25921 gcgcgcatca acgcccgtgc accggtctac accgtcaccc acggcgacat cgacctgggc
    25981 ctgctgttca acaccaacgg ttttatgctg gaagagaacg tcatcagcac caaaccgcgt
    26041 ttccacttta tcgcggataa acaaaacgat atttcgtcga ttgtggtgga actggattac
    26101 ccggtagata tcagcgaagt ttcccgggtg atggaaaacc tgctgctgga atcggcggat
    26161 aaactgctgc gttacaaagg gatgctgtgg attgacggcg aacctaaccg cctgctgttc
    26221 cagggcgtcc agcgcctcta cagcgccgac tgggaccgcc cgtggggcga tgaaaaaccg
    26281 catagcacga tggtgtttat cgggattcag ttgccggagg aagagattcg ggcggcgttt
    26341 gcggggttga ggaagtaatt atggatgatg gccgccatgt ggcggcctga attatttttt
    26401 gttctgatcg cgcagcatcg cttcacgtaa aattgcgttc aggcgagttt gatagccttt
    26461 accaggtcgc ttcagccatt ccatcacatc agcatcaata cgcaccgaag cctgggtttt
    26521 caatggccga taaaacttac cgcgttctgc gttagaccat tgctcatcgc tggaaggcgg
    26581 gatatcactg taatcaatat cttcgtcgaa tttattcgcc agtgccttca gttcggcctc
    26641 atgctgcaca tcgagtgtag agggtgtccc tcgtttatgt ttaaccatgc tcatagcggc
    26701 tcctctcttt acgatctgct tttcgtgcac tgatgattcg aataatttca tttccgcttt
    26761 cgaaacggat ggtatgcgca accagaataa ccacgatacc gtgaaccagg ccgatagtct
    26821 gccagcgata ctcaccgttt tctatgcgat cttgctgtga caaatgttgt ggatcatcaa
    26881 acactaacac cgcatcttca aagcggatgc catgtttcac ccgattactt ttggccttgt
    26941 ttgcatccca ttcaaactcc attggcatag ttgccatccc taattgtata tacaaaaatg
    27001 tatctacaat tattctgcaa ttatagcgtt gatgttggaa atagcatcac gttttggata
    27061 atcaaccatg aaattgacaa tgagtaagtt ggacttgatt catccaatag aatttctcgc
    27121 ctgacatggc acactaaaca cctcgctgtc gttaagggat taccgtgaaa aactataaag
    27181 ttattacccc gctttttcct acctatgcac aggttaaagc tatgatgaaa gccgtctcag
    27241 gctattccct gaaagcggta cgcaatatga ttaccgccat tcgcgatcaa accggtacgc
    27301 cgcaaaaacc cgttgactgg tcggaacctg acctgtggat cagcgaacgc ttaacgggcg
    27361 aagatgccga catcgcccgt cgtatttggg atacagataa tcacatattg aacccgcgcc
    27421 acagctacgg ctgctactta ttcctcaact atccccagtt tgagctgatg gaaagcacgc
    27481 cagatgatac ctggcagccc acctcgcgcg ggcaaaaatt cctgcaagat gacgaaaaaa
    27541 cgctgcgttc actggatgac caggaaggca ttctgcaact gcttgagctg ctggctggcc
    27601 gagaaatgtc gcgccgcgcc gatttattgc cggaatggca ggcctttttg catcagcatt
    27661 cgaaattcgc gtctgcaagt tcagtgaaaa gcacgctcta ctcccgtctc tataacctta
    27721 ttgaccgtgg catggttact cgcgaaggta tgagctattg catcaccgat accggacgcg
    27781 cctggcttgg aaaagcgttg ccagcacgaa aaagcgatcc gcgtaaagag ctgctggaag
    27841 cggtgaaacg ctacaacgag cagcaaaaag agctgctgcg cgaacaaatc agcacaatga
    27901 acccgtacaa atttgaacaa ctggtcggtc aattactgga agcaatgggc tacgagcagg
    27961 tcgaagtgac caaagcctca ggcgataaag gtgtggacgt gattggtcag gtgcaggtcg
    28021 gcatcaccac tattaccgaa gtggtgcagg tcaaaagaat gcagaacacc atcactcgac
    28081 cgtatatcga ccagttgcgc ggagcgttgc cttaccacaa ggccattcgc ggtacgctca
    28141 tcaccaccgg gaaatttgca gcgaaatgtg cagaagcggc gctctttccg ggggccgcgc
    28201 ccattacgct tatcgacggc gatcgcttac tggaactgtt aatcgaaaat aacgtcggca
    28261 ttcgccgcag caatgcagtg gaattgctgg atgtggattt gcagttgttt gatgagctgg
    28321 agatggatta aagggcgaaa tccgccgcct caaccattac aatagcgacc caatttatct
    28381 gaacagagtt catcatggcc aaagcaccaa ctaaaaaagc caaagcaaaa aaaggctttg
    28441 aagaaacatt atgggatacc gcaaaccaac ttcgcggtag cgttgagtcc tccgaataca
    28501 agcacgtggt gttaagcctc gtgttcctga aattcatcag cgataagttt gaagcacgcc
    28561 gcaaaaaaat gattgccgat gggcaagctg acttccttga gatggaagtg ttctaccagc
    28621 aggacaacat tttctacctg ccggaagagg cgcgctggtc gtttatcaaa caaaatgcca
    28681 aacaggacga tattgcggtt cgtattgaca ccgccctctc gacaattgag aaacgtaacc
    28741 caaccctgaa aggcgcgctg ccagacaact acttcagccg tcagaatctg gaaaccaaaa
    28801 aactggcgtc actgattgat accatcgaca acatcgaaac gctggcacac gaaactgacg
    28861 ttgaaacgtt gtcgaaagaa gacctggtcg gacgcgttta cgaatacttc ctcggtaagt
    28921 ttgccgcaac cgaaggcaaa ggcggtggag agttctacac gcccaaatgt gtggtcacgc
    28981 tgttaactga aatgctcgaa cccttccagg gcaaaattta tgacccgtgc tgcggctcgg
    29041 cagggatgtt cgtgcagtcg gtgaagttcg tcgagagcca tcagggtaaa agccgtgata
    29101 tcgcgctgta tggtcaggaa ctgacagcca cgacgtataa actggcaaaa atgaacctcg
    29161 ccattcgcgg tctttcagct aacctcggcg aacgcccggc aaacactttc tttagcgacc
    29221 agcacccgga cctgaaagcc gactacattc tggcgaaccc gccgttcaac ctgaaagact
    29281 ggcgcaatga agccgaatta accgaagatc cacgctttgc cggttatcgt atgccgccaa
    29341 ccggtaacgc caactacggc tggattttgc atatgctctc caagctgtcg gctaacggca
    29401 cagcaggttt tgtgctggca aacggttcga tgagttctaa caccagcggt gaaggcgaga
    29461 tccgtgcaca gatgatcgaa aatgatctga ttgactgcat gatcgcccta cctggacagt
    29521 tgttctacac cacgcagatc ccggtgtgtt tatggtttat gaccaaatcg aaggctgccg
    29581 acccggccaa aggttatcgt gatcgtcagg gcgagacgct gtttattgat gcgcgtaacc
    29641 tcggcaccat gattagccgc acaactaaag agttaacggc ggaagatatt gccacaatcg
    29701 ccgataccta ccatgcctgg cgcagcacgc cggaagaact ggctgcacgg attgcgcgtg
    29761 gtgacagcaa gctggaaaaa tatgaagacc aggcaggctt ctgcaaagtt gcgaccctgc
    29821 aagatattaa agataacgac tacgttctga caccgggccg ctatgtgggt gcagccgagc
    29881 aggaagaaga cggcgtggca tttgagacca aaatgcgtga attgtcgaag acgttgtttg
    29941 agcagatgaa gcaggcggaa gaactggatc gtgcgattcg ccagaatctg gaggcgctgg
    30001 gttatgggga gtaagtggtg tatatatcgc ttaggtgata tagctgaatt ttcatacgga
    30061 aaaatgccta aaaaggagtt tgttggtaca ggtgactatg tcattttttc aggatataaa
    30121 tacacagaaa gctaccctga aaaaaatact tcggcaggtg agttaattgt tgttgcccga
    30181 ggtgttggtg gaactggcga tgttaaaata acgactagag attgttattt aacaaatttg
    30241 tccattaaaa taaatttgga tgaaacaaaa gtaagaaaag aatattttta ttatctgttt
    30301 ctacagagta atttacgata tcttgatagc ggttctgctc aaagccaaat aaccatcaat
    30361 gatctagcga atgtagaaat atctgctcct tcgctaaatg ttcaagattt aatagtcaag
    30421 agtctcaaag cttttgatga caaaatcaca acactttcat ccatgaacca aaccttggaa
    30481 caaatgtccc aaaccctgtt caaatcctgg tttgtggatt ttgatccagt gattgataac
    30541 gctctggatg caggaaatcc aatcccggaa gccctgcaaa ctcgcgccaa attgcgtcaa
    30601 aaagtacgta atagtgcaga ttttaaaccg cttccggcgg aaattcgctc gcttttccca
    30661 agtgaatttg aagaaacgga gttgggttgg gtgccaaagg ggtggaaaga agggacgctt
    30721 ccagagatag cttttataaa ctccacatcg tggactaata aaaatcaacc agattatatc
    30781 aattatgtag atctctctaa tgcgaaagat ggcagaatat actcaattga aaaattatca
    30841 tttaatgatg ctccaagtcg agctcgaaga atattaaaaa aagatgatct gatttttggc
    30901 cttgtcagac ctgctaacag atcatttgca tatgtacatg ttgatggtct aacgggtagc
    30961 acaggctttg ccgttattag agcccaaaag acgatatata aaaatttcat ttattacttt
    31021 gtgacctatg ataaaaatat agaagaacta gcgagaattg ctgatggtgg agcatatcct
    31081 gctataaaac ctgatgatat ttgtacatta cctctaatta ttccatcaat aaatataatt
    31141 gagaaatttg atgaattaac aagcaatttc agagagatga tgaataactc attaattcaa
    31201 aacgaatatc tcaccaacct ccgaggcacc ttgctcccga aactcatctc cggcgagcta
    31261 tccctggaag atcttccgga tctcaccacc gatacagaag ccgcataacg cattttgccc
    31321 ctgtaaaatc aggggctttc tggtaaggtt ttctactgat acgggaatgc ttaccagaaa
    31381 ttagccaggg ttggagcgcg atatgagtct ctctttcagt gaagcaaaat tagaacaagc
    31441 gatcattgaa ctgttacagg atcagggata tcaacacctg atcggcgata atgtcccacg
    31501 ttcgagcctc gatcaggtca ttatcgaaga cgatctccgt cattatttag cggcacgcta
    31561 ccagcctgat ggcattactg aagaagagat tcagcgactg atcaaacagt tcaccacgct
    31621 tccggcctcc gatctttatg aaagcaacaa aacattttgt cgctggctgg caaatggttt
    31681 tctgttcaaa cgcgacgatc ggcaacaaaa agatctctat attgaattgc tcgacacccg
    31741 gcatctacct gccgcactgc gccagatatt tgacgccgaa gatgtcccgt tgcaacaggc
    31801 ggcggaactc ccgccttcct atatgaatcc gccgcttaac cggattaaga ttgttaacca
    31861 gcttaaaatc tccggcaaag ataatcagac tcgtattcct gacggcattc tctatatcaa
    31921 tggtctgcca ttggtcgtct ttgaatttaa aagtgcggtg cgcgagcagg aagccagtat
    31981 tggcgatgcc tggaagcagc tctgtaaacg ctatcgccgg gatattccgc aactgtttat
    32041 ctacaacgcg ctctgcatta ttagcgatgg cgtaaataac cggatgggca acctgtttgc
    32101 gccctatgaa tacttttact catggcgcaa agtcaccggt aatgaaaacc gtgaacagga
    32161 cggaattcca tcattgcact caatgattca ggggctgttt catccggtac gtctgctgga
    32221 tgtgattaaa aactttatct gcttcccgga taaagccaag cacgaagtaa aaatttgctg
    32281 ccgatatccg cagtactatg ccgcccgcaa actctattac agcatcaagc aagcgcgtaa
    32341 acctttcggt agcggtaaag gcggcactta ctttggcgca acgggctgtg gtaaaagtta
    32401 caccatgcaa tttttaacgc gtcttttgat gaagagcgtg gagtttgcca gcccgaccat
    32461 tgttttgatc accgaccgca ccgatctgga cgatcagctt tctgcgcaaa tgtgcaacgc
    32521 caaaaattac attggcgacg acaccatcgt tcccgttacc agccgtgaag atttgcgtaa
    32581 tcaactggca ggacgcaata gtggcggagt ctttctgaca acgatccata aattcaccga
    32641 agacaccgaa ctcctttctg aacgcaacaa tatcatttgc atctcggacg aagcacatcg
    32701 tagccaggtt aacctcgacc agaaagtcat cgttgataaa gaaagcggaa aagtgcgcaa
    32761 aacgtatggc tttgcgaaat acctgcacga ttcactgcca aacgccacct atgttggctt
    32821 taccggcaca ccgattgacg cgacgctcga tgtcttcggt gaggtgatcg acagttacac
    32881 catgaccgaa tccgttcagg atgaaatcac tgtacgcatc gtgtacgaag gccgtgcggc
    32941 taaagtgatc ctggactcca gcaaactgga agaagtcgaa aagtattacg aagagtgcgc
    33001 aaacgcaggc accaatgagt ggcaaatcga cgaaagcaaa aaagccaccg ccaccatgaa
    33061 tgcggttctg ggtgatgaag atcggttaaa agccctcgca gaagattttg ccaaacatta
    33121 tgaaaaacgc gtagccgaag gttccaccgt aaaaggcaaa gccatgtttg tttgtgccag
    33181 ccgtgaaatt gcctgggatt tctaccgtca gcttaaagct attcgccctg cctggtttga
    33241 agtgaagcaa gcacccgatg gcgtcgtcct gacggaacag gagcagaaag agttaccgcc
    33301 ttcagaaatg gtgaagatgg tcatgacgcg cggtaaagat gacgacgagg cgctttatga
    33361 tttactgggc acaaaagaat atcgcaaaga gctggataag cagttcaaaa acgctaaatc
    33421 gaatttcaaa attgccattg ttgttgatat gtggctgacc ggtttcgacg tcccggaact
    33481 ggataccatc tatattgata aacccttaca aaaacataat cttatccaga ctatttctcg
    33541 cgttaaccgt aaactggaag gcaaaagtaa agggttagtg gtggactaca tcggcattaa
    33601 aagtcagatg aaccaggcac tggcaatgta ttcccgcatt gatgccacca actttgaaga
    33661 tattcagcaa tcggtaatag aagttaaaaa ccatctcgat ttgttggggc aagtctttta
    33721 cgaatttgac agtcgggatt attttagtgg tgagccacaa gcgcaattat cctgcctcaa
    33781 ccgcgcggcg gaatttgttc tgcgtaccca gaaagttgaa cgtcgtttta tgggactggt
    33841 taaacgcatg aaagccgcct acgacgtctg ctgcggcagc gaagcattat cacagacaga
    33901 acgtgactat attcactatt atcttgctgt tcgttcaatt gttttcaaac tgacgaaagg
    33961 tgacgcaccg gatgttaccc agatgaatgc acgcgttcgt gaaatgattg cagaagcgtt
    34021 aaaagctgat ggcgtagaag aaatttattt tcttggcgat aaaaaagcgg aatccatcga
    34081 tatttttgac gaagattatc tggcgcgaat taacaagatc aaacttccgg caacgaagat
    34141 ccagttatta caaaaattac tggaaaaagc gatcagcgac ttcaagaaag tgaaccagtt
    34201 gcaagggatt aacttcaccc gccgcttcca ggcgattata gatcgttata atgagcggcg
    34261 agaagatgat gtactcaacg gtgaagaatt cgatacattc agtcaggaaa tgaccgatat
    34321 tatctatgat attaaaaccg aaatgggcac ctgggccgat ttaggcattg atattgaaga
    34381 aaaagccttt ttcgacattc ttgctcatat gcgcgataaa tatcagttca cctatgacga
    34441 tgaaaaaatg ctgtcactgg caaaagagat gaaaagcgtg gttgacaaca catctaaata
    34501 tcctgactgg agtaaacgcg atgatattaa agcgaaactg aaagttgaac ttattctgct
    34561 tctacacaag cataagttcc cgccagtagc gaatgatgat gtttatatgg gtgtgctggc
    34621 acaggcagag aattttaaag aacaccatat gagttcttta aattaattat gaaggccgga
    34681 tacactttgt tatccggcca ttctgaatta acgttaattt cccttccaga tctttccagt
    34741 aatgctttta ttattttcta tttttagctg gacttttccc atatttactg atgatatatc
    34801 caggtattta gcgcgatgcg gatgtgttgg cgcacacccg caccgctcat cacaatcact
    34861 atttataggg aatagcagtt atgactgaca cgcattctat tgcactaccg tttgaagcag
    34921 aagtctcccc ggcaaataac cgtcaattaa ccgtgagtta tgcgagccgc tacccggatt
    34981 acagccgtat tcccgccatc accctgaaag gtcagtggct ggaaaccgcc ggttttgcca
    35041 ccggcacggc ggtagatgtc aaagtgatgg aaggctgtat tgtcctcacc gcccaaccac
    35101 ccgccatcga agagagcgaa ctgatgcagt cactgcgcca ggtgtgcaaa ctgtcggtgc
    35161 gtaaacaaag gcaggtgcag gagtttattg gggtgattag tagcaaaacg ccacgctaag
    35221 tttctctccc cttccccaca cgggaagggg aattttcccc ctcactccac atcctccctg
    35281 cgtaacccaa tatccctcaa ccgctcatca ctcatctgct gtaacactcg tcgggtctgc
    35341 atttgccgcc gccaacgcct caccgcctgc cagagttgca caagtctgat aaacggcgtt
    35401 ttggctttgt tttcgtaaaa ttccatctgc tgcctcctca tctttcagag gcttcatcat
    35461 ccgtcttctg gcagttcaca atacagatgc aaatattagt tttatttaac atacagacag
    35521 attaaaacag catctgcatc cggtttttta gcctcatctg taccggtttt tctctctgta
    35581 tggtccaaat aaggaataca gcatgacgcg ttatcaacat ctggcgactc tacttgccga
    35641 gcggattgag caggggctgt atcgtcacgg ggagaaattg ccgtcggtgc gcagcttaag
    35701 tcaggagcac ggcgtcagca tcagcaccgt gcagcaggcg taccagacgc tggaaacgat
    35761 gaagctcatc actccgcagc cgcgttcggg gtattttgtc gcacaacgta aagcccagcc
    35821 gccagtgccg ccgatgacgc gtccggtgca gcgcccggtg gaaattaccc agtgggatca
    35881 ggtactggat atgctggagg cgcatagcga cagttccatt gttccgttaa gcaaaagcac
    35941 gccggatgtc gaaacgccca gcctgaaacc gctgtggcgg gagctaagcc gggtggtgca
    36001 gcataatctg caaaccgttc tcggttatga cttgttagcc ggtcagcgag tgttgcgaga
    36061 gcagattgcc cgcctgatgc tcgacagcgg ctcggtagtc accgccgatg acatcatcat
    36121 taccagcggc tgccataact cgatgtcgct ggcgttaatg gcggtgtgta aaccgggcga
    36181 tattgtcgcg gtcgaatccc cctgttatta cggttcgatg cagatgctgc gtggcatggg
    36241 cgtgaaagtg attgaaatcc caaccgatcc agaaacaggc atcagcgttg aagcgctgga
    36301 actggcgctg gagcagtggc cgattaaagg catcattctg gtgccaaact gtaataatcc
    36361 gctgggattt attatgccgg acgcgcgcaa acgggccgtt ctctctctcg ctcagcgtca
    36421 tgatattgtg atttttgaag atgatgtcta cggtgaactg gcaacggagt atccgcgccc
    36481 gcggaccatt cattcctggg atatcgacgg gcgagtgctg ctgtgcggct cgttcagtaa
    36541 aagtattgca cctggcctgc gcgtgggctg ggtcgcaccg gggcgctatc acgataaact
    36601 gctgcatatg aaatatgcca tcagcagctt taatgtgccg tccacgcaaa tggcggcggc
    36661 aacgtttgtg ctggaaggtc actatcatcg ccatatccgg cggatgcggc agatctatca
    36721 gcgcaatctg gcactttata cctgctggat acgggaatat tttccctgcg aaatctgtat
    36781 tacgcgcccg aaaggcggat ttttactgtg gatagaattg cctgaacagg tcgatatggt
    36841 ctgcgtcgcg cggcagctgt gccgcatgaa aatccaggtg gcggcaggct cgattttctc
    36901 ggcttccggc aaataccgta attgtctgcg caccaactgc gctttgccgc tcagcgaaac
    36961 ctatcgcgaa gcactgaagc aaattggcga ggccgtgtat cgggcaatgg aataaattcg
    37021 acatagtggc gaagcgcctg atttactctc acgaatagag tgtgactcgt tttatctttg
    37081 cagggtaatc gccacgttcc agcatggctt aggcaaagtg cgctttgttc ataccggatg
    37141 cgatgtgaac gccttaccag gtctacaaaa tctttaaagt taaatatatt taatgggtta
    37201 tgtagacctg ataagcgtag cgcatcaggc tgctttgcgt ttgtcatcag tctctgatta
    37261 gtactcgatc catggatcgc gcttgctttc aggcaagggc tgatctaatg cctgcatttg
    37321 ctctgccgaa agtccggtat atcgttgtat ccattcagga tccgccccat tctgcaacaa
    37381 caatcggagg aggctctttt ccccttcttc tttcccttct ttcctccccc tctcccttcc
    37441 caacagccat ccatcattat gaattcgctc tgcaatcgtc attattcgct ccctgtgttg
    37501 tggcattcga cggataagtt cgctgataaa ctcattaaaa cgcgcttcat cgccagtcag
    37561 taaaatgtaa tttaacagcg cggttatctg gctgtcatta gcgcaccctg taaccagtaa
    37621 tactgccagt tgatcaataa gccccattag atcgcgctgg cgaatatgct tttggatcaa
    37681 ctccagcagg gcgactctgc gatgctgcac aatctcgtcg tctggcacga cagtgacatc
    37741 caccagcggg aacgctgcgg tataaagctt ccgtgcggta gccgggtcgg caaattcatc
    37801 cagccagcac aaagaccagg ggtaaggact acggctaccg tgataaaaca gcatcgggat
    37861 gaccagcggt agcggccggc gtttatcatg ctcgatatgg cgctgcatca ccgccatgga
    37921 atatcgcatc aggcgaaagg ccatatggat atcctcgcgg ctctgatgtt caatcaccac
    37981 ataaatatag ccatctcctt cgcgggtctt taccgaccac agaatatcgg aatgtagcgc
    38041 ccgcaatttt tcatcgacaa agctggcgta ttccagtttt aagctgtcga gatcgcacag
    38101 ttcacgtaaa tctttgggta agtggatctc cataaaatcc cgcgcggtgt cagggtgggt
    38161 gagaaaagat ttaaataatg cgtcatgcgg cgtgctggtc gtgaagtttg tcatggcgat
    38221 ccgtcacctg tagataagat ggcccgactg tagcgactaa caaaaccatt ctcacccggc
    38281 aatttctcgt tccccgaggt gctttccagg ctatttttgt tcctctgcaa acgatacatt
    38341 tttccggaaa caggctcgca ttttacattt cctgtacccg gcagatattc ccctttccac
    38401 cgcactcttt tgattaaccg caaattttaa ttacacttaa ggtgtatatt ttctatgcaa
    38461 cccatcaatt caagaggtgt aatgtgctga tgactatttg taatcgttat acattctgac
    38521 ctggagtcag aaggtatttc tctgtctgta tgttcacagg cagtgtggtt gattacatga
    38581 aattcagtac atttgcccgt ctcgcctgcc tttcgtcatt accgacggta ttgaatttcg
    38641 ttttccccat tgggattctc cggacaagga gttgtttgtt atgccacgtt tttttgcccg
    38701 ccatgccgcc acgctgtttt tcccgatggc gttgattttg tatgactttg ctgcgtatct
    38761 gtcgacggac ctgatccagc cagggatcat taatgtggtc cgtgatttta atgccgatgt
    38821 cagtctggcc ccggctgccg tcagtctcta tctcgctgga ggcatggcat tgcagtggct
    38881 gctggggccg ctttccgaca ggattggccg caggccggtg ctgattaccg gggcgttaat
    38941 ttttaccctt gcctgcgccg cgacaatgtt caccacgtca atgacacaat ttcttatcgc
    39001 gcgtgcaatt cagggcacca gtatctgttt tattgccacc gttggttatg tcacggtgca
    39061 ggaggcgttc ggacagacaa aagggatcaa gttgatggcg attatcacct ccatcgtact
    39121 gattgcgccg attattggcc cgctttccgg cgcagctctg atgcactttg tgcactggaa
    39181 agtccttttt gccatcattg cggttatggg ttttatctca tttgtcggct tgctgctggc
    39241 gatgccagag acggtgaagc gcggcgcggt tccgtttagc gccaaaagcg tcttgcgcga
    39301 ttttcgcaat gtcttttgca accggctgtt cctctttggc gcggcaacca tcgccctcag
    39361 ctatatccca atgatgagct gggtggctgt ctcgccggtg atcctgatcg atgcgggcgg
    39421 cttaacaact tcgcagttcg cctggacgca ggttccggta ttcggcgcgg tgattgtcgc
    39481 caacaccatc gtggcgcgat ttatcaaaga tccgaccgaa ccgcggttta tctggcgtgc
    39541 cgtgcccatt caactggccg gcctcgcact gttgattgtc ggcaatttgc tgtcgccaca
    39601 cgtctggcag tggtcggtgc tcggcaccag tctgtatgct ttcgggattg gtttaatctt
    39661 cccgacctta ttccgcttta cgctgttttc caataactta ccgaaaggga ccgtctccgc
    39721 atcactgaat atggtgatcc tgatggtgat gtctgtctcg gtcgaaatcg gccgctggct
    39781 gtggtttaac ggcggtcgct tgccgtttca tctgttagcc gtcgtagcgg gcgttatcgt
    39841 cgttttcacc ctggcgggat tgctcaatcg cgtgcgccag catcaggctg ccgagctggc
    39901 ggaggagcgg tgatttttgc gcgatcctgc cgtcaggctc tattcttaac gttatgaata
    39961 aactcattga actcagacgc gccaaaatgt tggcgctctc tttactgctt atcgccgctg
    40021 ctacctttgt cgttacgctg tttttgccac ccaatttttg ggtgagcggc gtgaaggcga
    40081 ttgctgaagc ggcgatggtc ggcgcgctgg cggactggtt tgcggtggtg gcgctgtttc
    40141 gccgcgtgcc gattccgatc atttctcgtc atacggcgat tatcccgcgt aataaagacc
    40201 ggattggcga aaatctcggt cagttcgtgc aggaaaaatt tctcgatacc caatcgctgg
    40261 tggcattgat tcgacgtcac gaaccggcgt tgttgattgg caactggttt agtcagccag
    40321 aaaacgcccg ccgcgttggt cagcatctgt tgcagatcat gagtggtttt cttgaactga
    40381 ccgatgatgc gcgtattcag cgcctgctta agcgcgcagt ccatcgggcg attgataagg
    40441 tcgatctttc cggcaccagt gcgttgatgc tggagagtat gaccaaaaac gatcgtcatc
    40501 aggtgctgct ggatacgctg atcgcacagt tgatcgccct tctccagcgc gataaatcgc
    40561 gcaagtttat cgcccagcag attgttcgct ggctggagag tgagcatcca ctgaaagcca
    40621 aaattttgcc cactgaatgg ctgggcgaac atagcgcgga gttggtttct gacgcggtga
    40681 attctttgct tgatgatatt agtcgcgatc gtgcgcatca gatccgccat gcgtttgatc
    40741 gcgccacctt tgccctgatc gacaagctga aaaacgatcc tgaaatggca gcgcgaaccg
    40801 atgccgtaaa aagctatctg aaagaagatg aagcttttaa ccgctatctc agtgaattgt
    40861 ggggggattt acgggaatgg ctgaaagcgg atatcaacag tgaagattct cgtgtgaaag
    40921 aacgcatcgc acgagcgggt caatggtttg gcgaaacgtt aattgccgat gatgccttgc
    40981 gggcgtcgtt aaatggtcat cttgaacaag ccgcgcacca cgtcgcgcct gagttttccg
    41041 cattcctgac gcgccacatc agcgatacgg taaaaagctg ggatgcgcgg gatatgtcgc
    41101 ggcaaataga attaaatatc ggcaaagatc tgcagtttat tcgtgttaac ggtacgctgg
    41161 ttggcggatg tattgggctg attttgtatt tgctgtcgca gctcccggct ttgttccccc
    41221 tcggcaattt ttagaaatcc atgaaaaact aagtggctaa ccgcgagaga gatcaaataa
    41281 accgcactaa aagaatggta ataatgtggc ttcttttcat tatctcccgt ggtacgggga
    41341 aggaaaatca tgtcacttgt caccgatcta cccgccattt tcgatcagtt ctctgaagct
    41401 cgccagaaag gctttctcac cgtcatggat ctcaaggagc gcggcattcc gctggttggt
    41461 acctactgta cttttatgcc gcaagagatc ccaatggcag ccggtgcggt tgtggtttca
    41521 ctctgttcca cctctgatga aaccattgaa gaagcggaaa aagacctgcc gcgcaatctc
    41581 tgcccgctga ttaaaagcag ctacggcttc ggcaaaaccg ataaatgccc ctacttctac
    41641 ttttctgatc tggtggtcgg tgaaaccacc tgcgacggca aaaagaaaat gtatgaatac
    41701 atggcggaat ttaagcccgt tcatgtgatg caactgccaa acagcgttaa ggacgatgcc
    41761 tcacgcgcgt tatggaaagc cgagatgctg cgcttgcata aaacggtaga agaacgtttt
    41821 gggcacgaga ttagcgaaga tgctctacgc gatgccattg tgctgaaaaa ccgcgaacgt
    41881 cgcgcactgg ccaactttta tcatttgggg cagttaaatc ctccggcgct tagcggcagc
    41941 gacattctga aagtagtcta cggcgcaacc ttccggttcg ataaagaggc gttgatcaat
    42001 gaactggatg caatgaccgc ccgcgttcgt cagcagtggg aagaaggcca gcgactggac
    42061 ccgcgtccgc gcattttaat caccggctgc ccaattggcg gcgcagcaga gaaagtggtg
    42121 cgcgcaattg aagagaatgg cggctgggtt gtcggttatg aaaactgcac cggggcgaaa
    42181 gcgaccgagc aatgcgtggc agaaacgggc gatgtctacg acgcgctggc ggataaatat
    42241 ctggcgattg gctgctcctg tgtttcgccg aacgatcagc gcctgcaaat gctcagccag
    42301 atggttgaag aatatcaggt cgatggcgta gttgatgtga ttttgcaggc gtgccatacc
    42361 tacgcggtgg aatcgctggc gattaaacgt catgtgcgtc atcagcacaa cattccttat
    42421 atcgctattg aaacagacta ctccacctca gatatcgggc agctcagcac ccgtgtcgcg
    42481 gcctttattg agatgctgta aggagtggca gtggcatatt cgattggcat tgattccggc
    42541 tcaaccgcca ccaaagggat cttactggca gacggcgtga ttacgcgccg tttcctcgtt
    42601 ccaacaccct ttcgcccggc aacagcaatt actgaagcct gggaaactct gcgcgaaggg
    42661 ttagaaacaa cgccgtttct gacgctcacc ggctacggac ggcaactggt ggattttgcc
    42721 gataaacagg tgacggaaat ctcctgtcac gggctgggcg cacggtttct tgcgccagca
    42781 acgcgcgcag taatcgacat cggtggtcag gacagcaaag tgattcagct tgatgatgac
    42841 ggtaacctgt gcgatttcct gatgaatgac aaatgcgcgg cgggcaccgg gcgtttcctg
    42901 gaggtgatct cgcgcacgct tggcaccagc gtcgagcaac tcgacagcat taccgaaaat
    42961 gtcataccgc acgccatcac gagtatgtgc acagtgtttg ctgaatcaga agtgatcagc
    43021 ctgcgctctg cgggcgtagc gccagaagcg attctcgccg gagtgattaa cgcgatggcg
    43081 cggcggagcg ccaatttcat tgctcgtctc tcctgtgaag cgccgattct gtttactggt
    43141 ggcgttagcc actgtcaaag gtttacccac atgctggaaa gccatctggg aatgccggta
    43201 caaactcacc ctgatgcgca attcgctggt gcaattggcg cggcggtgat cggtcagcgg
    43261 cagagaaaac gcgcatgaaa gagtatctgt ttttatttca ctccacggtc ggcgtcatac
    43321 aaacccgcaa ggcgttgcag gcagcgggca tgacttttcg cgtcagcgat attccccgtg
    43381 atttacgcgg cggctgcggg ttatgcattt ggctgacctg tccgcctggc gaggaaattc
    43441 aatgggtgat ccctgggcat acggaatcag tttattgtca gcaggatggt ggctggcgct
    43501 gcattgcaca ttacgggatt tctccgcgtt aaggattcat taagatcgct acgtatactt
    43561 ctcgatatct tattgatttg ccttaaaggg attaccgtga caaaaagtat ttcgttaagt
    43621 aaacgcatct tcgttattgt gattcttttt gtcattgtgg cagtgtgtac attcttcgtg
    43681 caatcttgcg cccgtaaaag caatcatgca gcatcatttc agaattacca cgccaccatt
    43741 gacggcaaag aaattgcagg cataacgaat aatatctctt cgctgacctg gtcggcacaa
    43801 agcaatactc tttttagcac tatcaacaaa cctgccgcca ttgttgaaat gaccaccaat
    43861 ggcgatttga tccgcacaat tcctctggat tttgttaagg atctcgagac gatcgaatac
    43921 attggcgata atcagtttgt cattagcgat gagcgcgatt atgccattta tgtgatttca
    43981 ctgaccccaa actcggaagt aaaaatcctc aaaaaaataa aaatcccgct gcaggaatcc
    44041 ccaaccaatt gcggttttga aggattggcc tattctcgcc aggatcacac tttctggttt
    44101 tttaaagaga aaaacccgat tgaggtctac aaagttaacg ggctgttaag tagcaatgaa
    44161 ttgcacatca gcaaagacaa ggcactacaa cggcaattta ctttagatga tgtgtccggc
    44221 gcagaattta accaacaaaa aaatacgctt ctggtgctgt ctcatgaatc tcgcgcactc
    44281 caggaagtaa cgctggctgg cgaggttata ggtgaaatgt cactaaccaa aggcagtcga
    44341 ggtttgtcgc ataacatcaa acaggccgaa ggggttgcga tggatgcctc aggtaatatt
    44401 tatatcgtta gcgaaccaaa tcgtttttat cgctttaccc ctcaatcatc gcattaacag
    44461 gctggcatgt ttcacctttt tgttattaac ttgttaacaa caaaaatgac aaacaaggtt
    44521 aaacatgcct tcgccctcgc atcccgtaga acgcttttct ttcagcaccg cgcttttcgg
    44581 gatgctggtt ctgaccttag gtatgggttt aggccgcttc ctttatacgc ctatgttgcc
    44641 cgtcatgatg gcggaaggat cgttttcatt tagccagctc tcgtggattg ccagcggcaa
    44701 ctatgcgggg tatctggctg gcagtctgct attttcgttt ggcgcatttc accagccatc
    44761 gcgcctgcgc ccatttctgt tggcttctgc cctggcgagc gggttgttga tcctcgcaat
    44821 ggcatggttg ctgccattta ttctggtgtt attgattcgc gtcctggcgg gtgtcgccag
    44881 cgccggtatg ctgatttttg gttcgatgct gattatgcag cacacgcgcc atccttttgt
    44941 gctggcagct ttgttttctg gcgttggcat tggcatcgca ctgggcaatg aatatgttct
    45001 ggcaggcctg cattttgacc tctcctcgca aacgttatgg caaggcgccg gggcgctttc
    45061 tggcatgatg ctgattgcac ttacgctttt aatgccctcg aaaaaacacg ccatcacacc
    45121 aatgccattg gcaaaaacgg agcaacagat aatgagctgg tggttactgg ctattctgta
    45181 cggcctggcg ggatttggtt atatcatcgt cgcgacttac ctgccgctca tggcgaaaga
    45241 tgcaggctca ccattgttaa ccgcccatct ctggacgtta gtcggcttat caattgtgcc
    45301 tggttgcttt ggctggctat gggcagcaaa acgttggggg gctttgccct gcctgacggc
    45361 gaatttgctg gtgcaggcta tctgtgtgct gcttactctc gccagcgact cgcctctctt
    45421 gcttatcatc agcagtcttg gttttggcgg tacctttatg ggcacgacat ctctggtgat
    45481 gactatcgcc cgccaactga gcgtaccggg aaatctcaat cttttaggct ttgtgacgct
    45541 catttacggc attggacaaa tcctcggccc ggcgctgacc agtatgctcg gcaatggaac
    45601 atcggcgctt gccggcgcca ctctctgcgg cgcggcggcg ttgtttattg ctgcgcttat
    45661 cagcacagta caattattta agctgcaagt ggtcacttca tgaggagtgt ttcccttacc
    45721 actcaagaaa ttcgaccgca accgttgatg tcagccagac cccgttttcc gcttgccaga
    45781 aagggaggcc tcgtttcgcc atttcctgtg ctttgacggt taaaataacc ggcgatccgt
    45841 gtcttgctcc cactttgcgt gccgttgctt catcagcaga gagatgtacg tagtgacgct
    45901 cacctgcaat cagcccctgt ttttttatct cgtcaaggaa acggcttgcc gtaccgtggt
    45961 agagaaactg tggcggtgtt ttttcggcaa aggaaatagc gacctgcgaa gtcgaatgcc
    46021 cctgaaccgc gcggatgcac ctaccatcac tggaataact aaaacgcttt ttatcgctgg
    46081 tggcaaccac ggtatccagc aatgcacggg ttaaccgctt gcccactttt tgggcacaaa
    46141 gtatgagctt atcgatatcc gcccatcctt cacggtccag tacgatacca atcgcctccg
    46201 gtttgtgtcg gaggacaaaa cttaaaaact tgctcgtatc cgccagctct ttttcgttgt
    46261 actttgccat cgcgttttcg tccctggatt atctgttttt tatttactat gtcattgtca
    46321 ctgggtttat gaattttctg caactcaatc ctgcgtagaa ccttttccac acagcgtaat
    46381 tttaccgcta tgcaaaaaac gcatagtcag aaacatactt gcattttccc catacccaca
    46441 tggctgataa ggtttttcag ctccaggaat tttcctggct caagcaacac acaaacacaa
    46501 aaaaacaatg gggattgtta tgacacaaca aggggatgct gtagccgggg agctggcgac
    46561 agaaaaagtg ggcattaaag ggtatctggc tttttttctc accataatct ttttttccgg
    46621 tgttttttcc gggacagaca gttggtggcg cgtttttgat ttttccgttc tgaacggatc
    46681 gtttgggcaa ctgcctggtg cgaacggagc caccacctcg tttcgcggcg cgggtggcgc
    46741 gggggctaaa gatggctttc tctttgcgct ggagctggca ccgtcagtca ttctctctct
    46801 ggggattatt tcaattaccg atggtcttgg cggattacgc gccgcgcagc agttaatgac
    46861 gccagtgcta aaaccgttgt tgggcattcc agggatctgc tcgctggcgc tgatcgctaa
    46921 cctgcaaaac accgatgccg ccgcaggtat gaccaaagag ctggcgcagg aaggtgaaat
    46981 taccgaacgc gataaagtga ttttcgccgc atatcaaacc agcggtagcg ccattatcac
    47041 caactacttc tcttccggcg tcgcggtgtt tgcctttctg ggcacgtccg taatcgtacc
    47101 tttagcagtc atcctggtgt ttaaatttgt cggagccaac attttgcgcg tctggcttaa
    47161 cttcgaagaa cgtcgcaacc caacgcaagg agcgcaagca tgacaactca ggtccgcaaa
    47221 aacgtcatgg atatgtttat cgatggtgcg cgccgtggct ttactatcgc cacgaccaac
    47281 ctgctgccaa acgtggtgat ggcgtttgtc atcattcagg cgctgaaaat taccggcctg
    47341 ctcgactggg tggggcatat ctgtgaaccc gtaatggcgc tgtggggatt acccggtgaa
    47401 gcggcaaccg tccttttagc cgcattaatg agtatgggtg gcgcagtcgg tgttgccgcc
    47461 agtctggcaa ccgctggcgc attaaccggt cacgatgtca ccgttttact gcccgcgatg
    47521 tatttaatgg gcaacccggt gcaaaatgtc ggtcgctgcc tggggacagc cgaagtgaat
    47581 gccaaatatt acccgcatat cattacggtc tgcgtgatta acgcattgct gtcgatctgg
    47641 gttatgcagc ttattgttta acaaggagtt accatgattg attataccgc agccggtttt
    47701 accctgctgc agggagcgca tttgtatgcg ccggaagatc ggggaatttg cgatgtcctc
    47761 gtcgctaacg gcaaaattat cgccgttgcc agtaatatcc cttctgacat tgtaccggac
    47821 tgcacggttg tcgatctcag cgggcagatc ctctgcccag gttttattga tcaacacgtc
    47881 catttgattg gcggtggcgg cgaagcaggt cccacgacgc gcacgccgga agtggcgtta
    47941 agtcgtctga cggaagcagg cgtcacgtca gtggttggtc tgctgggcac cgactctatc
    48001 tctcgccacc cggaatccct gctcgccaag acccgtgcgc tcaatgaaga aggcatcagc
    48061 gcctggatgc tgaccggcgc ttatcatgtc ccttcccgca ctattacggg ttccgtggaa
    48121 aaagacgtgg cgattatcga tcgcgtgatt ggcgtgaaat gcgccatctc tgatcaccgt
    48181 tctgccgcac cggacgttta tcacctggct aatatggcgg cggaatcccg cgttggcggt
    48241 ttgctcggcg gtaaacctgg cgtcaccgtg ttccacatgg gcgacagcaa aaaggcgtta
    48301 cagcctgtct atgacctgct ggaaaactgc gatgtgccga ttagcaagtt gctgccgacc
    48361 cacgttaacc gcaacgttcc gttgtttgag caggcgctgg agttcgcgcg caaaggcggc
    48421 accatcgata tcaccagcag cattgacgaa ccagtcgccc ctgccgaagg tattgcccgc
    48481 gccgttcagg cgggtattcc gctggcacgc gtcaccctca gctccgacgg caacggtagc
    48541 cagccgttct tcgatgacga agggaattta acccatatcg gtgttgccgg ttttgaaacg
    48601 ttgctggaaa ccgtgcaggt gctggtcaaa gattatgatt tcagtatcag cgatgccctg
    48661 cgcccgctca ccagtagcgt agccggtttc cttaacctga gcgggaaagg cgaaattctg
    48721 ccaggcaatg acgcagactt actggtcatg acgccagaat tacgcattga gcaggtatac
    48781 gctcgcggca agctgatggt caaagacggc aaagcctgcg tgaaaggaac gtttgaaacg
    48841 gcataaacgg ttgtcagccg cccgaatgga cgtagaatgc ccgcaagggc ggctgacaga
    48901 gtaaaacgta atggatgact gtggtgcggt tttgcataat attgaaacta aatggcttta
    48961 tgattttctg accctggaaa aatgccgcaa tttttcccag gcagcagtca gtcgcaacgt
    49021 ctcgcaaccg gcattcagcc gccgcatccg tgcgctggaa caggcgattg gcgttgaatt
    49081 gtttaaccgc caggtgacgc cgctgcaact ctcggaacaa ggtaaaatat tccattcgca
    49141 gatccgccat ctgttgcaac agttagagag caaccttgca gaactccgtg gtggcagcga
    49201 ttacgcgcaa cgcaaaatta aaatagccgc tgcacactct ctttccctcg ggctgttacc
    49261 gtccattatc agccagatgc cgccgctctt tacctgggca attgaagcta ttgatgtcga
    49321 tgaagcggtc gataaactgc gtgaagggca aagtgactgt attttttcct ttcacgacga
    49381 agatttgctg gaagcgccgt ttgaccacat tcgcttattt gaatctcaat tgttccccgt
    49441 ttgcgccagt gacgaacacg gagaagcact ttttaacctc gcgcagccac actttccgtt
    49501 actgaattac agccgcaact cctacatggg gcgattgatt aatcgcaccc tgacgcgcca
    49561 cagtgagtta agtttcagca ccttttttgt ctcttcgatg agcgagcttt taaagcaggt
    49621 tgccctcgac ggctgtggga ttgcctggct accggaatac gccatccaac aagaaattcg
    49681 cagcgggcag ctcgttgtac tgaatcggga cgaactggtg atcccgattc aggcctatgc
    49741 ataccggatg aatacccgca tgaatccagt tgccgaacgc ttctggcgtg aactgcgcga
    49801 gctggagatt gtgcttagct gacattctcc agcgtcgcac tgcgccaacc gccattatcc
    49861 cagaccagat caaacgttag cgattcatcg tcgtgataca gcattatctc aaggctgatc
    49921 gccagagtgt ggcagtacgc ttctttcaaa ttaacctgta acgccgcaat ccgtggctca
    49981 tgaaataaca gtgcagaacg cagctgacgg caataccagc tctggagatg tttgtcgctc
    50041 gggttatgca cttgccactc gggcatgcct gaaacaagta atgacggtaa tgccgaatga
    50101 ggagaattaa aaagagtgag gagatcgctg catactgatt tacgcagcgg tgacgtttta
    50161 ttgcctgaaa tttcaggtaa aacagcctga agtgattggc gcatcatttt gcgcactcct
    50221 gacgtttagc aacatatgcg gcttgccctg aacaccgggc accactgtat tgatgctcat
    50281 tttccatagc cattcccttt tgttcattac atccatgtca gtctgagaca ggcctgaatc
    50341 ctgtcagcaa agtataaaac cttacttgcc tatgaatatc tactgacttt tcaggaaaaa
    50401 agtcatgatt tgataaaaat catcaaactc aaaaaaaaac cgctagtata ttctgaatat
    50461 tccgaatagt tacgtagatg aaaatacttg tcaccaccgc tacttaattc cggt
//
LOCUS       DAPOXO010000030        47728 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPOXO010000030 DAPOXO010000000
VERSION     DAPOXO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47728
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.030"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            27..659
                     /gene="comR"
                     /locus_tag="ROH59_002096"
     CDS             27..659
                     /gene="comR"
                     /locus_tag="ROH59_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HDX4804576.1"
                     /translation="MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDHYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIARTTLRLWPELLK"
     gene            complement(721..1260)
                     /locus_tag="ROH59_002097"
     CDS             complement(721..1260)
                     /locus_tag="ROH59_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDX4804577.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKV"
     gene            complement(1487..2791)
                     /gene="ndh"
                     /locus_tag="ROH59_002098"
     CDS             complement(1487..2791)
                     /gene="ndh"
                     /locus_tag="ROH59_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HDX4804578.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
     gene            complement(3190..3732)
                     /locus_tag="ROH59_002099"
     CDS             complement(3190..3732)
                     /locus_tag="ROH59_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4804579.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            complement(3755..4780)
                     /gene="nagZ"
                     /locus_tag="ROH59_002100"
     CDS             complement(3755..4780)
                     /gene="nagZ"
                     /locus_tag="ROH59_002100"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HDX4804580.1"
                     /translation="MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRE
                     LVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISARLNQLHERW
                     QEEKAGH"
     gene            complement(4791..5615)
                     /gene="thiK"
                     /locus_tag="ROH59_002101"
     CDS             complement(4791..5615)
                     /gene="thiK"
                     /locus_tag="ROH59_002101"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HDX4804581.1"
                     /translation="MPFRSNNPLTRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRL
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTDQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            complement(5596..6237)
                     /gene="lpoB"
                     /locus_tag="ROH59_002102"
     CDS             complement(5596..6237)
                     /gene="lpoB"
                     /locus_tag="ROH59_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HDX4804582.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPTEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            complement(6251..6628)
                     /locus_tag="ROH59_002103"
     CDS             complement(6251..6628)
                     /locus_tag="ROH59_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HDX4804583.1"
                     /translation="MRKGCFGLVSLALLVLVGCRSHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            complement(6631..6990)
                     /gene="hinT"
                     /locus_tag="ROH59_002104"
     CDS             complement(6631..6990)
                     /gene="hinT"
                     /locus_tag="ROH59_002104"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HDX4804584.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            7324..9513
                     /gene="fhuE"
                     /locus_tag="ROH59_002105"
     CDS             7324..9513
                     /gene="fhuE"
                     /locus_tag="ROH59_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HDX4804585.1"
                     /translation="MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPATEETV
                     IVEGSATAPDDGENDYNVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDRSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTKWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRNLSITGTYQF"
     gene            complement(9573..11006)
                     /gene="ptsG"
                     /locus_tag="ROH59_002106"
     CDS             complement(9573..11006)
                     /gene="ptsG"
                     /locus_tag="ROH59_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HDX4804586.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLT
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(11301..12098)
                     /locus_tag="ROH59_002107"
     CDS             complement(11301..12098)
                     /locus_tag="ROH59_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX4804587.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            complement(12109..13113)
                     /gene="holB"
                     /locus_tag="ROH59_002108"
     CDS             complement(12109..13113)
                     /gene="holB"
                     /locus_tag="ROH59_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDX4804588.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNALGIDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYGVQSGDWYSLLAALNNEQAPARLHWLATLLMDALKRHYGAAHVTNVDVPGLVVE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            complement(13110..13751)
                     /locus_tag="ROH59_002109"
     CDS             complement(13110..13751)
                     /locus_tag="ROH59_002109"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDX4804589.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTNWVKELDA"
     gene            complement(13741..14763)
                     /gene="yceG"
                     /locus_tag="ROH59_002110"
     CDS             complement(13741..14763)
                     /gene="yceG"
                     /locus_tag="ROH59_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HDX4804590.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDQVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            complement(14766..15575)
                     /gene="pabC"
                     /locus_tag="ROH59_002111"
     CDS             complement(14766..15575)
                     /gene="pabC"
                     /locus_tag="ROH59_002111"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HDX4804591.1"
                     /translation="MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTAYPAHYDRLRNEGMTLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEEALQADEMVICNALMPVMPVRACGDVSFSSATLYEYLAPLCERPN"
     gene            complement(15695..16936)
                     /gene="fabF"
                     /locus_tag="ROH59_002112"
     CDS             complement(15695..16936)
                     /gene="fabF"
                     /locus_tag="ROH59_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDX4804592.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            complement(17024..17260)
                     /gene="acpP"
                     /locus_tag="ROH59_002113"
     CDS             complement(17024..17260)
                     /gene="acpP"
                     /locus_tag="ROH59_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDX4804593.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            complement(17471..18205)
                     /gene="fabG"
                     /locus_tag="ROH59_002114"
     CDS             complement(17471..18205)
                     /gene="fabG"
                     /locus_tag="ROH59_002114"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HDX4804594.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            complement(18218..19147)
                     /gene="fabD"
                     /locus_tag="ROH59_002115"
     CDS             complement(18218..19147)
                     /gene="fabD"
                     /locus_tag="ROH59_002115"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDX4804595.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            complement(19163..20116)
                     /gene="fabH"
                     /locus_tag="ROH59_002116"
     CDS             complement(19163..20116)
                     /gene="fabH"
                     /locus_tag="ROH59_002116"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HDX4804596.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLTANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            complement(20184..21254)
                     /gene="plsX"
                     /locus_tag="ROH59_002117"
     CDS             complement(20184..21254)
                     /gene="plsX"
                     /locus_tag="ROH59_002117"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDX4804597.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            complement(21335..21508)
                     /gene="rpmF"
                     /locus_tag="ROH59_002118"
     CDS             complement(21335..21508)
                     /gene="rpmF"
                     /locus_tag="ROH59_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDX4804598.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            complement(21560..22081)
                     /gene="yceD"
                     /locus_tag="ROH59_002119"
     CDS             complement(21560..22081)
                     /gene="yceD"
                     /locus_tag="ROH59_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HDX4804599.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            22280..22864
                     /gene="yceF"
                     /locus_tag="ROH59_002120"
     CDS             22280..22864
                     /gene="yceF"
                     /locus_tag="ROH59_002120"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HDX4804600.1"
                     /translation="MPELILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            complement(22976..23935)
                     /gene="rluC"
                     /locus_tag="ROH59_002121"
     CDS             complement(22976..23935)
                     /gene="rluC"
                     /locus_tag="ROH59_002121"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HDX4804601.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDDGLKRCLQKLRNAR"
     gene            24508..27693
                     /gene="rne"
                     /locus_tag="ROH59_002122"
     CDS             24508..27693
                     /gene="rne"
                     /locus_tag="ROH59_002122"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HDX4804602.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKSAPATPAAPA
                     QPGLLSRFFGALKALFSGGEETKPSEQPTPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     PRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQTPRRERSRR
                     RNDDKRQAQQEVKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETVAAEPIVQEAAAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVQVQPMVTEVPVAAAAEPVVSAPVVEEVAEVVEAPVQVAEPQPEVVETTH
                     PEVIAAAVTEQPQVITESDVAVAQEVAEHAEPVVEPQEETADIEEVAETAEVVVAEPE
                     VVAQPAAPVVAEVTAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQR
                     PTFAFEGKGAAGGHTATHHASAAPARPQPVE"
     gene            complement(27888..28841)
                     /gene="flgL"
                     /locus_tag="ROH59_002123"
     CDS             complement(27888..28841)
                     /gene="flgL"
                     /locus_tag="ROH59_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDX4804603.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTESAPFSEADGKYEGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLNK"
     gene            complement(28853..30496)
                     /gene="flgK"
                     /locus_tag="ROH59_002124"
     CDS             complement(28853..30496)
                     /gene="flgK"
                     /locus_tag="ROH59_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDX4804604.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPA
                     VLQNTKNKGDVAIGATVTDTSAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASAEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSTTQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            complement(30562..31503)
                     /gene="flgJ"
                     /locus_tag="ROH59_002125"
     CDS             complement(30562..31503)
                     /gene="flgJ"
                     /locus_tag="ROH59_002125"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HDX4804605.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPIKFPLETVVRYQNQTLSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF"
     gene            complement(31503..32600)
                     /gene="flgI"
                     /locus_tag="ROH59_002126"
     CDS             complement(31503..32600)
                     /gene="flgI"
                     /locus_tag="ROH59_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HDX4804606.1"
                     /translation="MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            complement(32612..33310)
                     /gene="flgH"
                     /locus_tag="ROH59_002127"
     CDS             complement(32612..33310)
                     /gene="flgH"
                     /locus_tag="ROH59_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HDX4804607.1"
                     /translation="MQKNAAHTYAISSLLALSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            complement(33364..34146)
                     /gene="flgG"
                     /locus_tag="ROH59_002128"
     CDS             complement(33364..34146)
                     /gene="flgG"
                     /locus_tag="ROH59_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HDX4804608.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            complement(34318..35073)
                     /gene="flgF"
                     /locus_tag="ROH59_002129"
     CDS             complement(34318..35073)
                     /gene="flgF"
                     /locus_tag="ROH59_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HDX4804609.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLVVQTADGSEGYTRN
                     GSIQVDPTGQLTIQGHPVVGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAESQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            complement(35093..36298)
                     /gene="flgE"
                     /locus_tag="ROH59_002130"
     CDS             complement(35093..36298)
                     /gene="flgE"
                     /locus_tag="ROH59_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HDX4804610.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDSLPSVNAFDASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWDVYTLDSSDP
                     TGTANPATTLVFNANGVLTSDPTKDITTGAINGADPATFSLSFLNSMQQNTGANNIVA
                     TTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWSA
                     TQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQ
                     ILNTLVNLR"
     gene            complement(36323..37018)
                     /gene="flgD"
                     /locus_tag="ROH59_002131"
     CDS             complement(36323..37018)
                     /gene="flgD"
                     /locus_tag="ROH59_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HDX4804611.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSISGQIDNSQSLQASNLIGHGVMI
                     PGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNNGNTLDLGT
                     YGTTTLDEVRQII"
     gene            complement(37030..37434)
                     /gene="flgC"
                     /locus_tag="ROH59_002132"
     CDS             complement(37030..37434)
                     /gene="flgC"
                     /locus_tag="ROH59_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDX4804612.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            complement(37438..37854)
                     /gene="flgB"
                     /locus_tag="ROH59_002133"
     CDS             complement(37438..37854)
                     /gene="flgB"
                     /locus_tag="ROH59_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDX4804613.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPSAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            38009..38668
                     /gene="flgA"
                     /locus_tag="ROH59_002134"
     CDS             38009..38668
                     /gene="flgA"
                     /locus_tag="ROH59_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HDX4804614.1"
                     /translation="MLTIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVR
                     VSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIVRGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAVSLRDLSPDQPIQLTHFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMISGQVVSGVVDADGNILIN
                     L"
     gene            38744..39037
                     /gene="flgM"
                     /locus_tag="ROH59_002135"
     CDS             38744..39037
                     /gene="flgM"
                     /locus_tag="ROH59_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HDX4804615.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            39042..39458
                     /gene="flgN"
                     /locus_tag="ROH59_002136"
     CDS             39042..39458
                     /gene="flgN"
                     /locus_tag="ROH59_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HDX4804616.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEIAVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTPYRGSKKISI"
     gene            complement(39498..41033)
                     /gene="murJ"
                     /locus_tag="ROH59_002137"
     CDS             complement(39498..41033)
                     /gene="murJ"
                     /locus_tag="ROH59_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDX4804617.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGILQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(41143..42066)
                     /locus_tag="ROH59_002138"
     CDS             complement(41143..42066)
                     /locus_tag="ROH59_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDX4804618.1"
                     /translation="MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALP
                     ICDSWRIPYADSLSSLAASCDAVFVHSSTASHFGVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATASSLRMDKHRTNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGNATLESGTLLTNESGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVDCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            complement(42068..42715)
                     /locus_tag="ROH59_002139"
     CDS             complement(42068..42715)
                     /locus_tag="ROH59_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HDX4804619.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRE
                     SRYMHLFSGEVENPPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            complement(42726..43310)
                     /gene="rimJ"
                     /locus_tag="ROH59_002140"
     CDS             complement(42726..43310)
                     /gene="rimJ"
                     /locus_tag="ROH59_002140"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HDX4804620.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALSAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            43546..44754
                     /gene="mdtH"
                     /locus_tag="ROH59_002141"
     CDS             43546..44754
                     /gene="mdtH"
                     /locus_tag="ROH59_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415583.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HDX4804621.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSY
                     MGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKR
                     AARRLLERDA"
     gene            44818..45465
                     /gene="grxB"
                     /locus_tag="ROH59_002142"
     CDS             44818..45465
                     /gene="grxB"
                     /locus_tag="ROH59_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HDX4804622.1"
                     /translation="MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            45598..46158
                     /locus_tag="ROH59_002143"
     CDS             45598..46158
                     /locus_tag="ROH59_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX4804623.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            46264..47307
                     /gene="pyrC"
                     /locus_tag="ROH59_002144"
     CDS             46264..47307
                     /gene="pyrC"
                     /locus_tag="ROH59_002144"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDX4804624.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVK"
     gene            47384..47629
                     /gene="dinI"
                     /locus_tag="ROH59_002145"
     CDS             47384..47629
                     /gene="dinI"
                     /locus_tag="ROH59_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HDX4804625.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
BASE COUNT        11542 a        12901 c        11856 g        11429 t
ORIGIN      
        1 tcacagtcac caggtacaac ggcatcatgg caactgactc aacacaatgt gtaaaaaaaa
       61 gccgtggccg cccaaaagtg ttcgacaggg atgccgcgct tgataaggcc atgaaattgt
      121 tctggcagca cggttatgaa gcgacttctc ttgcggacct cgttgaagcg accggagcta
      181 aagcgcccac gctatacgcg gaatttacca acaaagaggg gttattccgc gccgtactcg
      241 accactatat cgatcgtttt gccgccaagc atgaagcaca gctgttttgt gaagagaaaa
      301 gcgtggagtc tgcgctggct gactattttg ctgccatcgc caactgcttt accagcaaag
      361 acactccggc tggctgcttc atgatcaaca actgcaccac cctctccccg gattcaggag
      421 atatcgccaa tacgctgaaa tcacgccatg cgatgcaaga gcgcactttg cagcagtttt
      481 tatgtcaacg acaagcgcgc ggggaaatcc cgacccactg tgacgtgacg catctggcag
      541 aattccttaa ttgtattatt caggggatgt cgatcagcgc acgcgaaggt gcatcactgg
      601 aaaaactgat gcagattgcc cgaacgactt tgcgtttatg gccggaactg ctgaaatagg
      661 tcgcaaaaaa agcccctcag cctgagcgaa tgaggggcta aattgcagag tacagccttg
      721 ttatactttg ttattcaaaa tcagctgccc gttgctatct agcgggatct gcgtacccgg
      781 atcgcggtcc atgcggattt tgccctgctg atcgccaatc ttataggtca catcataacc
      841 gagcattttt tctgacttgt catacaccgt tttacaacgc tgttgcgtag tcgtgtaagt
      901 atcgctttcc tggagagagc cctggatctg gttacctgca tatccacccc ccagcgcccc
      961 cacaacagtg gcgacatctt taccgcgacc acctccaaac tgatgcccaa tcacgccgcc
     1021 agcaacagcg ccgagcaccg acccggtaat gcgattttca tcctgcaccg gtcgacgatg
     1081 ggtcactgta acgttgcgac actcctgacg cggtgtttta accgtttcct tgattggggt
     1141 tgcagaaaca acctgagcgt attgcgggcc acgttcaaac acgttcagac tggccactgc
     1201 cgctacgccc agcgcagctg cgacaccaat cccgataccc gccaacattg acttattcac
     1261 gggaacacct ccttctttgt agttatgcca atcatgcaag cgaaggagaa aagcagctat
     1321 cagacagaag atgaaaagcg cgggaatggc tggaaatact cagggattcg gaggagtctg
     1381 aaggaatgcc tgatgcgacg cttaacgcgt cttatcaggc ctaccgctcg taccatttgt
     1441 ccagggcgga taaggcgttt atgccccatc cgccagtaca agtcgattaa tgcaacttca
     1501 aacgtggacg gataacgcgg ttaatactcc ccaccagcat cattaatccg gttttaaagt
     1561 aaccatgcag cgcaatctgg tgcattcggt acagcgagat gtatacaaag cgcgcaattc
     1621 gtccttcaat catcattgag ccgcgcgtca ggttacccat caggctaccg actgtggaaa
     1681 agttcgacag cgataccagc gaaccgtgat ctttatactg ataatttttc agcggcttac
     1741 cgttcatctg cgccagaatg ttgttcattg cgcaggttgc catctgatgt gcggcctgag
     1801 cgcgcggcgg aacaaagccc ccttccggac gcgggcatga cgcgcagtcg ccaatagcgt
     1861 atatgtctgg atcgcgagtg gtttgcagcg tcggttccac caccagctgg ttgatacggt
     1921 tggtttcaag accaccgata tctttcagga agtctggcgc tttgatcccg gctgcccaca
     1981 ccatcagatc agcctcaata tattcgccat ctttagtgtg caggccgcct tcatcagcac
     2041 tggtgaccat ggtttgcgtc agcacgcgaa cgccaagttt cgttaactca ctatgggccg
     2101 cagcagagat acgtggcggc aatgcaggca aaatacgttc gcccgcttct accagcgtta
     2161 cgttcagggc ttcgttggtc agacctttat aaccgtaact gtgcagttgc ttgaccgcgt
     2221 tgtgcaattc agcggagagt tctacacccg tcgcgccgcc gccgacaatc gcaatgttta
     2281 ctttgccatt cgcgcccagg ttggcggagt atttcaggaa cagattcagc atctcctggt
     2341 ggaagcgacg cgcctggtgc gggttatcga ggaaaatgca gttctctttg acacctggtg
     2401 tattgaaatc gttagaggtg ctacccagcg ccattaccag ggtgtcatag gcgattttac
     2461 gttccggaac cagcagttca cctttctcgt cgcgcagttc tgcaatagtg attgttttcg
     2521 cttcacgatc aatatcaatt acggaaccca gctggaactg gaaaccatga ttgcgcgcat
     2581 gggccagata gctcaacgca tcgacgcctt catcaagcga gccagtcgcc acttcgtgca
     2641 gcagcggttt ccacaagtgg ctgtggttac gatcgaccag cgtaattttg gcttttttct
     2701 tgcgtcccag cttatgcccc agctgtgttg ccatttccag cccaccagca ccgccgccga
     2761 caatcacaat ttttttcaat ggcgtagtca acgtgacccc cttaaattta ttaaccaatt
     2821 gttaattaat ggttattaac atagctctta attaacaaca ggttatagca atgaaaatgt
     2881 tcttcgctat tgagaataac atgaatggtg cattggtcat accaaaattg atgttaatca
     2941 agttttgttg ctgaaaagat aggcgacttt accgggtgag atcaaaaaac agagtttgtt
     3001 gttcattatt tgagctgatt tgtgagaatg atatagagtg aggtgtgtat ggagggcgtt
     3061 cggtaggcct gataagaggc gcatcaggca ttgatgctcg actgtcggat gcggcggaac
     3121 gccttatcca acccacagaa tcaggagcgc atcaggtacc ggcaaggtta cctgatgcga
     3181 cgagggcatt tacccgaggg ttttgaacgc tttaatgcgc tgtaaatgcg gggagatatt
     3241 cttgaatttg tgcgtctgct cttcgtccca gacaatctcg taataatgat gcaactcttc
     3301 agatgtccgc tggctgttaa gcgcttcatc attacgcgac aaaatcacca ggcaacgatc
     3361 gcgattcttc tcacggaagt tggtcacaca cttagtggca atatcggcat actcttccgg
     3421 gcgatcaatc ttcccttcca tgttctcata agggaacaaa ttggggttga agatcacctg
     3481 gcggatatca cagagaaaac caatccgctc agcccaataa ccgcccagac caacaccaca
     3541 aatgagcggg cgctcgtcga cgttcagttg caacattttg tccacttctt tgagcaaatg
     3601 ctgcatatca tgttttggat gccgcgtact gtagcttatt agccgtacat ccgggtcaat
     3661 aaactgcaat tgtaagactt tctcgtggtt acccggactg ttagagtcaa aaccgtgcaa
     3721 atagataatc atcgcttcct cacataagcc agggttaatg acctgccttc tcttcctgcc
     3781 agcgttcatg taactgattc agacgggcgc tgatcgcttt ccagcgagcc gagtccatca
     3841 gttcctgtcg cgaaaatgaa cctttatgat acaaacgtgt aacacgttct gccttgatcg
     3901 gtgacagatt atctaacacg ctgacggccc ctttacgatt attgcagacc aggatcatat
     3961 cgcaacctgc atccagtgat gcctgtccac gctcggcata actgcccata atcgctgcgc
     4021 cttccatcga taaatcgtca gagaaaatca cgccgtcaaa acccaattcc tgacgcaaaa
     4081 cggttttcag ccagtaggga gaaccgctcg ccggacgcgg atcaacatca ctgtagatca
     4141 catgcgcagg cataatggcg tcgagtttat tttcgcggat taaggaactg aagaccgaca
     4201 tatctttagc gcgaatctcc gcttgcggac gtgggtcgca cggtgtttct ttgtgtgagt
     4261 ctgccgttac tgcaccgtga cctgggaagt gtttcccggt agttttcatt ccggcttcat
     4321 gcataccatc aataaaccgg ctggcaattg ccagggcttt ttgtggatcg gcatgataag
     4381 aacgctcgcc aatcgccgcg ctgatatgcc cgacgtccag cactggcgca aagctgatat
     4441 caatatccat agcaatcatt tcgctggcca tcaaccaacc tgcctcttgc gccagttttc
     4501 cgccttcttc cattcccaac agcgcagcga atgattgtgc cgctggcaag cgggtaaaac
     4561 cttcacgaaa acgctgcacg cgtccacctt cctgatctac cgccaccacc agatgatttc
     4621 gcgatgctgc gcggatctgg cgcaccagtt cacgtaactg ggcaggatca tgatagtttc
     4681 gcgtaaagag aatcagccct cccaccagcg gatgcgccag tatttcacgc tcttccgcgt
     4741 ccagttcgta accttcgaca tccaacatta ctggacccac actgctctcc ttattgtttt
     4801 attaatagct gccgccaggt gtcatcggcc agcctgataa attgttgatc gccggtttgt
     4861 cgccagcggt actcaaacca ccctgctttg agcatcagca gccagggaaa ccatcgcctg
     4921 acctgacgcc ataattgcgc cggataaatc ttcgcgcgag tggcatagtc attgaccaat
     4981 tgccgatgct ggtcagtatt ttccacccac accgccgcca gttccagcgc gatatcacca
     5041 tctccggcat actcccagtc gatgagtttt aaccctgacg cgctatgcac taaatttccg
     5101 gcgtggacat ccatatgcaa tggacttaag cgtaaaagcc gtggttcccg cgctttgcgc
     5161 agacgtttta acattcgcag ccaacccact gtccgccgcg ccggatcgct ttgctgccag
     5221 tacagttcca gtaacggcaa cagcgttatt cgccagccaa aacgcggttg ttgatgtaga
     5281 taatacagca agcctgccag ttcgttggta tccggcaaat acgtttttac ctcgccgggc
     5341 agatagtcaa ccaccatcca gtcacggaga tataaatgcg gcttcggtgc aatgcatgcg
     5401 ggtagttgtg ataaagcccg atactggcgc aagaacgcgg actgcggcgc atcaggatcg
     5461 tgcggctgac gcacaacaaa acgctggccc tgatgttcaa tgagaaaact cccgccacta
     5521 agcccactat taaacgtcgt gacgggatga aactgcggga aaaagcgcga cagcaattcg
     5581 tcgcgcgtga ggggattatt gctgcgaaac ggcaccttta cctgaccaga taatttcgcc
     5641 cgtctgcacc agcatcagct gcatttgtag ggtcggagcg ttaacgttgc cagaggcgct
     5701 ggagtacagc acgtaatgag cgccaacatt gcgggcaatg cctatggctt tactacgggt
     5761 gcctaaactg tcctgcggcg acaaacctaa ttgttgctta gccatcgaca gctgctgggc
     5821 ggaaaccagg gtaaatttac cgttattagc cagcgcattt cgcagcgttt cggtcgcttc
     5881 tgcggcattc aacgaaccgt tagtacggtt gttaacgcta tcaaccagca ggacgctacc
     5941 cgcagtcacg ccatcagccc caagcatctt actgaccatc ggctgcattg cgccattcca
     6001 gtcataatgg cgaatatgcg gcgcaggcgg tgcagtttga tcttcgtgct caattgggcc
     6061 tggctgctgc ggtatcgtcg gcaccgatgg cactgtgggg acaggctgtt gtggctcggt
     6121 tggttgttcc ggcgctggtt tcacttcttc taccggtgca ggttcacgtt gccccacaca
     6181 cccggcaaga aacatcgcca gcgcggtaat caaggcgtag cgactcattt ttgtcatcaa
     6241 gattcacccc ttacaaatat agataaagtc tgactttgtg cgcccccaga aaattggcgc
     6301 tgccgtacag cgtgaccgcc gaatgtgcgg gaatggtaac gctgcgtggc ctttccagag
     6361 gatgcatctc cagccctctg gcgtcatacc agtaaaaacg ataatgaacg gtaacgggtt
     6421 cttgcctttc gttataaagc gttgaggatg ctgaaggttg aatatcagat gtcgaaagga
     6481 cgggcttttc tgcactgatg cccgcagcca ataaagatga ctccatcacc agcgattgct
     6541 catcattcac cggaatttcc ggatgtgaac gacagcccac cagcactaac aacgccagag
     6601 acaccagccc aaagcatcct tttctcatcg ttacagacct ttatgcgcca gcattggtcc
     6661 cagcggacgg ccacccaaca agtgcatatg gatgtggtaa acctcttgtc cgccatggcg
     6721 gttggtgttc atgatcagac gatagccatc ttcggcaata ccttcttgct cagcaatttt
     6781 tgccgctacg gtgatcatgc gtcccagcgc ctgctcatgc tcagctgaca cgtcgttcac
     6841 agtcggaatg aggatattcg gaatgatcag aatatgcgtt ggcgcttgcg gcgaaatatc
     6901 gcgaaacgcc gttaccagat catcctggta gacgatatcg gaggggatct cacgacgaat
     6961 aattttgctg aatatagttt cttctgccac gacattttcc tttttcaaat agccatgcgt
     7021 tgcgccatgc tacgccgcgc cacactgcga gtatagagta tggtcgagtt aaacctgctc
     7081 tttcaacctt aactcacgat ttcttaagca aaaaaccgtt ttgctgccgt atatatcgcc
     7141 attattccca tttctgcctg cgaatgcgct gaaaagacat tttctgtttg gtttacacac
     7201 caaatatgaa tgcgtatatt tctcatttgc atttacatac aaaattattc gcacactaaa
     7261 tataaccgct catcaccctg ctccggcatg agcctgacgc caacataaac caagagattt
     7321 caaatgcttt cgacacaatt taacagggat aatcaacatc aagccatcat caaaccgtca
     7381 ctccttgccg gttgcatagc actggcacta ttaccttccg ccgcttttgc tgcaccagcc
     7441 actgaagaaa cggtgattgt tgagggttca gccacagccc cagatgatgg cgaaaatgat
     7501 tacaacgtaa cgtctacctc tgcgggtaca aaaatgcaga tgactcaacg tgatattcct
     7561 cagtcggtca ctattgttag ccagcagcgg atggaagatc agcagttaca aacgctgggc
     7621 gaagtgatgg aaaacacgct ggggatcagc aaaagtcagg cggattccga tcgtgctctt
     7681 tattattccc gcggattcca gatcgataac tatatggttg atggtatccc cacctatttt
     7741 gaatcgcgct ggaatctggg cgacgcactt tctgatatgg cactgtttga acgcgtagaa
     7801 gtagtgcgtg gcgcgacagg cctcatgacc gggacgggta atccatctgc ggcaattaat
     7861 atggttcgaa aacacgcgac cagtcgtgaa tttaaaggcg atgtctcggc ggaatacggt
     7921 agctggaaca aagaacggta tgtggcggat ttacaaagcc cactcaccga agacggtaaa
     7981 atccgcgcac gaattgtcgg cggctaccag aataacgact catggctgga ccgctacaac
     8041 agtgaaaaga ccttcttctc cggcattgtc gatgctgatt taggcgatct tacgatgctt
     8101 tcagccggtt acgaatatca gcgtattgat gttaatagcc caacctgggg cggtttaccg
     8161 cgctggaata ctgatggcag cagcaacagt tacgatcgcg cacgcagtac cgcacctgac
     8221 tgggcgtaca acgataaaga gatcaacaag gtctttatga ccctgaagca gcggtttgct
     8281 gatacctggc aagcgacgct gaatgccacc cactctgaag tcgaatttga cagcaaaatg
     8341 atgtatgtcg atgcctatgt aaacaaagcg gatggtatgc tggttgggcc atacagtaat
     8401 tatggccctg gttttgatta tgtcggaggc accggttgga acagcggcaa acgtaaagtt
     8461 gatgcgctgg atctgttcgc tgacggtagt tatgaattgt ttggtcgtca gcacaattta
     8521 atgtttggtg gcagttacag caaacaaaac aatcgttact tcagttcatg ggccaacatt
     8581 ttcccggatg aaattggcag tttctacaac tttaatggca atttcccaca aaccgacagg
     8641 tcaccacaga gtctggcgca ggacgatacc acacatatga aatcgttata tgctgccact
     8701 cgtgtcaccc ttgccgatcc gctgcatctg atcctcggcg cacgttatac caagtggcgg
     8761 gttgatacgc tgacttacag catggagaaa aaccacacca cgccttatgc tggactggtg
     8821 tttgacatca atgataactg gtcgacctac gccagctata cctctatttt tcagccgcaa
     8881 aatgatcgtg acagttcagg caaatatctg gcaccaatca ccggtaacaa ctacgagctg
     8941 ggtctgaaat cggactggat gaatagccgt ctgaccacca cgttagccat cttccgtatt
     9001 gagcaggata atgtcgctca gtccaccggt acacctatcc ccggcagcaa cggcgaaacc
     9061 gcctataaag cggtggatgg gacagtcagt aaaggtgtgg aatttgaact caacggcgca
     9121 attaccgaca actggcagct gacgtttggc gcaacgcgct atattgcaga ggataacgaa
     9181 ggaaacgccg ttaatcctaa tctgccacgc accacggtta aaatgttcac cagctatcgg
     9241 ttgcctgtca tgccagagtt gacggtcggc ggtggtgtta actggcaaaa tcgcgtgtat
     9301 accgacaccg tgacaccgta tggcaccttc cgcgccgagc aaggtagcta cgcgctggtg
     9361 gatctcttca cccgctacca ggtgacgaaa aacttctcgt tacaggggaa cgtcaataac
     9421 ctgttcgaca aaacctacga taccaacgtg gaaggttcta ttgtctacgg cgcaccgcgt
     9481 aatttaagca ttaccggcac gtatcaattc tgaataacgc ctgtaaaaaa ggcagccatc
     9541 tggctgcctt agtctcccca acgtcttacg gattagtggt tacggatgta ctcatccatc
     9601 tcggttttca ggttatcgga tttagtaccg aaaatcgcct gaacaccaga accagcaacc
     9661 actacgcccg ctgcgcccag tttcttcagg ccagcctgat ccactttaga cacatcagca
     9721 acgctgacgc gcagacgggt aatacatgcg tcgaggttag taatgttttc tttaccacca
     9781 aatgcagcaa ccagagccgg tgccatttcg ctggtacctg tcgcttttgc gtcttcagtc
     9841 gcgtcttcac gacccggcgt tttcagatcc agtgctttaa tcagcacgcg gaagatggtg
     9901 tagtaaacaa tggcataacc gataccgacg atcgggaaca gccacagttt gctgctgtta
     9961 ccagacagaa cgatgaagtc gatcagaccg tgcgagaacg acgtaccgtc acgcatcccc
    10021 agaagaatac agattgggaa tgccaggcct gccagaatcg cgtggatgat gtacaggatc
    10081 ggcgcaacga acatgaagga gaactcgatc ggctcggtga taccggtcag gaacgaggtc
    10141 agcgccgcgg agatcataat accgcccact ttcgcgcggt tttctggttt agcagagtgc
    10201 cagatagcaa ttgcggcagc tggcagaccg tacattttga acaggaagcc accagacagt
    10261 ttacccgcag tcgggtcacc cgccatataa cgcggaatgt cgccgtggaa aacctgacct
    10321 gctgcgttgg tgtattcacc aatctgcatc tggaaaggta cgttccagat gtggtgcaga
    10381 ccaaacggta ccaggcaacg ttcgatgaaa ccgtaaatgc caaacgcaac taccgggttc
    10441 tggtaagcag cccactgaga gaaggtctgg attgcagagc caataggcgg ccaaatgaag
    10501 gacagcacaa cgccagtaaa gatggcagtc aggcctgaaa tgatcggcac aaagcgttta
    10561 ccggcaaaga agccaagata ctcaggcagc ttaatacggt agaaacggtt aaacatgtac
    10621 gctgcgatcg caccggagat aatccccccg agtacgccag tatccgccag gtgtttagag
    10681 gcgatttctt cagcaggtaa atgcagtacc agtggcgcaa ccacggccat ggttttaacc
    10741 atgatgccat aggcaacaac tgcggccagc gcggatacgc catcgttatt ggtaaagccg
    10801 agggcgacac cgatcgcaaa aatcagtggc atgtttgcaa agacggaacc gcctgcttct
    10861 gccataacat gcgatacaac ggcgggcagc cagctgaaat tcgcggaacc gacgcccagc
    10921 agaatacctg cgataggcag tacggatacc ggcagcatca gcgatttacc gaccttttgc
    10981 aggttagcaa atgcattctt aaacataatt gagagtgctc ctgagtatgg gtgctttttt
    11041 tacgttctca cgcgtggcaa ggggggagtg cctcgccgtg tacagggcat ctaagcgccc
    11101 tttatttatt acacagagta aaataattca gtgccgattt gtttgacggc tatcacgttt
    11161 caacttcaga tcattggaga agttgcacat tttgacaaaa catatgtcac aatatttcaa
    11221 acgtggttat tcaccgcccg attttcggcg gtgaacttta ctcgttttag ccattaatta
    11281 cgagctttaa aaaaactcat tcaacggatg gattgaaggc gggaagcatc gatgtgaaac
    11341 agacgggcga agttatcggt ggttacctgc gccagttctt caacggcaac acctttcaac
    11401 acagccatgt attctgcaac gtcacgaacc atcgcaggtt gattctcttt tcctcgatgc
    11461 ggtactggcg caaggtaagg tgagtcagtt tccaccagta accgatccag ggggacataa
    11521 cgcgcagcat cgcgcagttg ctccgcatta cggaaggtca caatgccgga aaaggagatg
    11581 taaaatccga gatccagtaa tttacccgcc gtttctctgt cctctgtaaa acagtgtagt
    11641 acgccaccgc aatccgtcac tttttcttcg cgcagaattg ccagcgtatc ggcgcgggcg
    11701 tcacgggtgt ggacgataac cggcttgttc agttcacgac caatctggat atgatggatg
    11761 aaggactctt gctgacgtac tttagtttcc ggcgtgtaat aataatccag cccggtttca
    11821 cccagcgcta caacgccctc ttctgccgcc agacgacgta aatcttctac atcgtaggga
    11881 tcattctggt tgagtggatg cacgccacaa gaaaatacga cgttgtcgcg ttcgcctacc
    11941 agatcccgca tgtgtaaata acccggtaat gttgtggcga ctgccagaca aaatttcaca
    12001 tcgcgtgcgg cggctttcgc cagaacgtca tccacgtcct tatgcaaaga ttcataatcc
    12061 agaccatcga gatggcagtg tgagtcgact aaaaacatga tgtctctctt aaagatgagg
    12121 aaccggtagc acaacgcccg gttgcaggta atgctcaata cgcagtaaaa gatcggtgat
    12181 gagaagctcg cggttgatac ctgtgacaga cattaactgt tcacgaatgt ggcaaacatc
    12241 ccccagtata gcctgcaggc gcgagggaga aagatggttt gccagttcga cgaccagccc
    12301 cggcacatca acattggtca cgtgcgcagc gccataatgg cgttttagcg catccatcag
    12361 caacgttgcc agccagtgta aacgcgccgg agcttgttca ttattaaggg ccgctagcag
    12421 cgaataccag tcgcccgatt gcacgccata tgccagcgcc tgacacaatg tttcacgagc
    12481 ctgccagtta tctccctgaa acaacgccag tgccgcccca ggcgaaccgg cgcttaagcg
    12541 caatgcggca agtagtgcat cctgtgacat tgtcacttcg cgtgaaagcc aggtcacggc
    12601 gtactgttcc ggcggcggcg caaggtaatg taaccgacaa cgactacgta atgttgccag
    12661 taaacgttct ggctcgcggg tagcaaggaa aaaccacgtc tctgctggtg gctcttcaag
    12721 cgttttcagc aatgcgttag ccgcggcgtc ggttagtaag gcagcatcgg ttacccagac
    12781 aactttcgca ccacctaagc gtgcgtgctc attcagcttt tcggtgacct cacgtaccgc
    12841 atcaatgccc agcgcatttt tccctttttc gggagccagg gtgtagtaat cgggatgtgt
    12901 gccagcctgc atcaactgac atccacgaca gtgaccgcaa cttttgtggc cctgcggttg
    12961 ttggcagagt aaataacggc tcagggcgta gattaaagca tcatcgccca tgcccggtaa
    13021 cgcctgaatg agtagcgcat ggtgacctct tccggcctga tagctggcta ccagtttttc
    13081 gaaatcaggt cgtaaccatg gataccatct catgcgtcca actccttcac ccaattggtc
    13141 acggtagtgc ggattgcatc catcacggcc tccagcggct gggtggcatc aatggtatga
    13201 atgcttttat cttgtgctgc cagttccaga tagcgggcgc gggtgcgatt aaagaaatcg
    13261 aatgactctt gctcaatacg atccagctca ccacgggcgc gagcacgttt taagccgacc
    13321 tctggggtga catcaagata aagcgttaag tcagggcgaa aatccccgag aacagcatca
    13381 cgcagtgttg ccagcatatg ttggtcaata ccacgtcctc caccctgata ggcttgagtg
    13441 gagagatcgt ggcgatcgcc aatcacccag gtgccgttag ccagcgcagg tttgatgacc
    13501 gtttctacca gttgaacgcg cgcggcataa aacatcaaaa cttcggcttt atcggtaatg
    13561 acttcatcgc ctaccgattt gatatccagc accaggcttc ttaacttttc ggcaagttgc
    13621 gtaccgccag gttcccgagt gaaaaccatg tcgcggatac ccagttgctc aagcgtctca
    13681 accaccacgt tacgcgcggt agttttgcct gcgccttcca gcccctcaat gacgatatac
    13741 ttactgcgca tttttttcct taagcacttt cagataatcc tgcacagact tgttatgact
    13801 ggcaagattg gtattaaacg tgtgaccacc tttaccatcg gccacaaaat agagatacgg
    13861 cgtttttgcc ggatgcgcag cagccttcag cgaatccgcc cccggcgtcg ctatcgcacc
    13921 tggcggcaga ccggtaatgg tataggtgtt atacgctgtc ggcgtttcca ggtctgcacg
    13981 agaaagtttg ccattataac gctctcccat cccgtaaatc acggtcgggt cggtctgcag
    14041 gcgcatacca atgcgtaaac ggttgataaa tactgaggca acctgatcgc gttcactggc
    14101 aacggcggtt tctttttcga taattgatgc catcgtcacc aactggtttt tatctttata
    14161 aggcagaccg tccgcacgcc cttcccaggc gctatcgacc gctttcacca ttttcttgtg
    14221 cgctcgtttg agtaacgcga catcggtggt attggcggta tacatccagg tgtctggcca
    14281 gaaccaacct tcaatccact ccgggttttc cagttcaagt gcctgcgcta cggtggcgta
    14341 cttatcgtcg ctcagcgtgt gcttgatata cggagcctca cgcaattgct tgaggtagtc
    14401 gctcagacgc atcccttcta ccagtcgcag cgggaactgt gcttctttac cgctttccaa
    14461 caatttcagc atctcgcgca cggtcatctg cggtgtaaag cggtaagtcc cggctttaaa
    14521 gtgagaaaga tccggttcga tacgcagcag ccattggaaa acccgtgggc gattgatgat
    14581 cttatcggca taaagctgtt caccgagcgc cagacgtccg gtccctggct tcagggtaaa
    14641 tatcgtctct tctttgataa gcaatttgct gtcggcaaga tggcgaacct tccagacgcc
    14701 cacaccagcg gcgataccca gtaccaccag caataacaag attatcaata acactttttt
    14761 catgactaat tcgggcgctc acaaagtggg gctaaatatt catataacgt tgctgacgaa
    14821 aaggagacat cgccacaggc acgtacgggc atcactggca ttaacgcatt acaaataacc
    14881 atctcatctg cctgcaacgc ctcttccaga gaggcttgca cttcgacaag ctgataagag
    14941 gattgtgcca gcaaacggat acagaattgt cgcataatgc cgttaacacc tgcctgatcc
    15001 agtcgcggcg tataaactac gttgcccttc cgccagaaca aattagccgc acagcattcc
    15061 gtaacccacc cttcgctgtc aaggaccagc gcctcatcag cgtttgtctg ctcaagatga
    15121 gagcggatca atacttgctc aagccgatta agatgtttaa tacctgcaag atgaggattg
    15181 cgccccagcc gcaccgggct tagcgccaac gtcatccctt cgttacgcaa acggtcgtaa
    15241 tgtgcaggat aagccgtaac ggagagaatc cgcgttgccg gtccactgtt caatgtgctg
    15301 taccctcgcc cgccactacc gcgactgatc acgactttca gtacaccatt ttgctgttct
    15361 gctgccagcg ttttcatctc ttgttcaagc tgaggccaga agtcacagga aatcatcaac
    15421 cgctgacaag catcctgtag tcgctggata tgcgccgata acaaactgac tttaccgtcg
    15481 ataactctgg cggtggtaaa acaaccatca ccaaactgcg ttgcccgatc gcttactgcc
    15541 agcgattcct gcttatgacc gttaattaag aacataccgg ctccttatca gagaattgtt
    15601 agtgtggcag catgttcact acggaacaag tcggaataaa agctaagaaa aaaggcccgc
    15661 aagcggacct tttataaggg tggaaaatga caatttagat ctttttaaag atcaaagaac
    15721 cattagtgcc accgaagccg aaggaattac acagagtgta ttccattccg ctaacctgac
    15781 gcgcttcgtg cggtacgaaa tccaaatcgc aaccttcatc cgggttatcc aggttgatgg
    15841 ttggcggaac agcctgatcg cgcagcgcaa ggatggagta gatagattct actgcacccg
    15901 ccgcacctaa caggtgaccg gtcatagatt tcgtggagct taccaacacg cggcttgcag
    15961 cttcaccgaa gatggttttc accgcctgcg cttcagcttt atcgccagcc ggcgtagaag
    16021 taccgtgcgc gttaacgtag ccaatctgac tcgcttcaat gcctgcatca cgcagagcat
    16081 ttgccatcgc cagagctgcg cctgcgccat tttctggcgg tgacgtcata tgataagcat
    16141 cgctgctcat accaaagccg acgagttcag cgtaaatttt cgcaccgcgt tttttcgcgt
    16201 gttcgtactc ttcaagtacc agcataccgg caccatcgcc cagtacgaaa ccatcacgct
    16261 ctttatccca cgggcggctc gccgcttgcg ggttatcatt gcgggtagat aatgcgcgtg
    16321 ccgcgccaaa accaccaacg cccagcggcg tactggcttt ctctgcgcca cctgcaacca
    16381 tcacgtcagc atcgccatac gcgataatac gcgcagcatg gccaatgttg tgcacgccgg
    16441 aagtacaggc ggtcgcgata gagatgcttg ggccacgcag gccatacatg atagtcagat
    16501 gacctgccac catgttcaca atcgttgacg gaacgaagaa tgggctgatc ttacgtggac
    16561 caccgttcat cagagatgtg tggttttctt cgatcagtcc gaggccgcca atcccggagc
    16621 caattgcggc accaatgcgg gttgcgttct cttccgttat ttcaaggcca gaatcctgca
    16681 tggcctgaac gccagcgaca attccatatt gaatgaaggc atccatcttg cgctgttctt
    16741 tgcgcgagat aatgtcctca cagttaaaat cctttactaa gccagcaaat ttcgttgcat
    16801 aggcgctagt atcgaaatgg tcgattaggc tgatgccact ctgaccggca agcagagctt
    16861 tccaggtaga ctctacggta ttgccgacag gagacaacat gcccagtccg gtcacaacta
    16921 cacgacgctt agacacgttt gtcctccagg gagggaaaaa atgattctag tgggacaaaa
    16981 agataaaact caggcggtcg aacgaccgcc tggagatgtt cacttacgcc tggtggccgt
    17041 tgatgtaatc aatggcagcc tgaacggtgg tgattttctc agcttcttcg tccggaatct
    17101 cagtatcaaa ctcttcttcc agagccatta ccagctcaac ggtgtcaaga gaatccgcgc
    17161 ccaggtcttc aacgaaagaa gcattgttgg taacttcttc ctgcttaacg cccagctgtt
    17221 cgccgataat tttcttaacg cgttcttcga tagtgctcat actcttaaat ttcctatcaa
    17281 aactcgcttt cgcgatggtt ttcgtagtgt ataaaatgtt gaaaaatttg caactaaatc
    17341 ccggcaggtc ttaccacgat tttacgttat tttgaggcct taccccccaa taacgcaaat
    17401 cattttgcac taattattac tcataaccac gcagactgcg cgcaacatga gcattttgtg
    17461 caaatcgcgg tcagaccatg tacatcccgc cgttcacatg caaagtttca cccgtgatgt
    17521 aagctgcttc gtcggatgcc aggaatgcaa ccgcgttggc gatttcctgt gcgccgccga
    17581 ggcgacccgc aggaacctgc gccaggatac ccgcacgctg gtcatcgctc agcgcacgtg
    17641 tcatgtccgt ttcaataaag cccggagcaa caacgtttac agtaataccg cgtgacgcaa
    17701 cttcgcgcgc cagtgattta ctgaagccga tcaagcccgc tttcgccgca gcgtagttgg
    17761 cctgaccgcc atttcccatg gtaccaacca cagaaccgat agtgataata cgaccatgac
    17821 gctttttcat catagcgcgc attaccgctt ttgacagacg gaaaacagat gaaaggttgg
    17881 tttcgataat atcgttccac tcttcatctt tcattcgcat taacaggtta tcacgagtga
    17941 taccggcatt attgaccagg atatccactt caccaaattc tgcgcgaatt ttttccagaa
    18001 cagattcgat agatgccggg tcggtcacat tcaacatcag acctttgccg ttggcaccta
    18061 aataatcact gatcgcctga gcgccatttt cactggtcgc agtgccaata actttcgcgc
    18121 cacgggctgc gagcgtttca gcaattgcgc ggccaattcc gcggcttgca ccggttacca
    18181 gtgcgatttt tccttcaaaa ttcatgattt tcctctttta aagctcgagc gccgctgcca
    18241 tcgctgaagg ttcgttcagc gccgaggcgg tcagggtgtc gacaatgcgt ttcgtcaggc
    18301 cagtaagcac tttgcccggg ccgacttcat agagatgttc tacgccttgc gctgccatgt
    18361 attcaacaga cttcgtccac tgaaccgggt tatacaactg acgtaccagt gcgtcacgaa
    18421 tggcatcacc attggtttcg catttcacat caacgttatt cacaacagga actgttggtg
    18481 cgttaaaggt gattttcgct aattctactg ccagtttgtc ggctgctggt ttcatcagcg
    18541 cacagtgaga cggtacgctc actggtagcg gcagagcgcg ttttgcgccc gcagctttac
    18601 aagcagcacc cgcacgctca accgcttctt tatgaccggc aataaccacc tgtcccggag
    18661 agttaaagtt taccggagaa acgacctgac cttctgcagc ttcttcacac gctttcgcaa
    18721 tagacgcatc atccagaccg atgattgccg ccatagcacc cgttccttcc ggtacggctt
    18781 cttgcatgaa cttgccgcgc atctcaacca gacgcaccgc atcagcgaaa tcaatcacac
    18841 cagcgcaaac cagcgcggag tattccccca ggctgtgacc ggccatcatt gccggtgctt
    18901 taccgccctg ctgctgccat acgcgataca gcgcaacaga tgcagtcaac agcgctggct
    18961 gggtttgcca ggttttattc agttcttcag ctggcccctg ctgggtcagc gcccacaggt
    19021 cgtagcccag cgccgcagaa gcttcagcaa acgtttcttc gacaattgga tagctcgccg
    19081 ccatatcagc cagcattcca acggtttgag aaccctgtcc agggaacaca aatgcaaatt
    19141 gcgtcatgtt ttaatcctta tcctagaaac gaaccagcgc ggagccccag gtgaatccac
    19201 cgccaaaggc ttcaagcaga accaactgcc ccggcttaat gcgcccgtcg cgtacagctt
    19261 catccagagc gcacgggaca gaggccgcag aggtattacc gtggcgatcc agcgtcacca
    19321 cgacattgtc catcgacatg ccgagttttt tcgctgttgc actgataata cgcaggttag
    19381 cctgatgcgg aaccagccag tccagttgag aacggtcaag attattcgcc gtcagcgtct
    19441 catcaacgat gtgcgccagt tctgttaccg caaccttgaa gacttcgttg cccgccatcg
    19501 tcagatgaat tgaattctct ggattcacac ggtcagcatt aggcagcgtc agcaactcac
    19561 catagctacc gtcggcatgc agatgggtgg agatgattcc cggctcttca gaggcagcca
    19621 gcaccgcagc gcccgcgcca tcgccaaaaa taataatagt cccacgatct gttggatcgc
    19681 aggtgcgcgc cagtacatcg gaaccgacga ccagagcata cttcaccgcc ccagatttca
    19741 cgtattgatc ggctacgctt aatgcatagg tgaaacctgc gcaggctgct gcaacgtcaa
    19801 atgccgggca acctttaatg cccagcatgc tttgaatctg acaagctgcg ctcgggaaag
    19861 cgtgcgtagc agaagtcgtt gccacaacga tcaggccaat ctggtctttc tcaatgcccg
    19921 ccatctcaat tgcgcgtgtc gccgcttcaa agcccatggt tgaaacggtt tcgtttggcg
    19981 cggcaatgtg gcgttcgcgg ataccggtac gagtgacaat ccactcgtca gaggtgtcca
    20041 ccattttttc caaatcggcg tttgtccgca cttgttcggg cagatagctg ccagtaccaa
    20101 taatcttcgt atacatgtac gctcagtcac ttttcggtta tataccgtca cttgcaaact
    20161 gcgagttcgc tggcagcgtc ctgctaccgc agagttccgc ttttgccacc gtccagcagc
    20221 tcaaaaccag ctgggtatac agattccagg cgagcggcaa ttcgctgagg aacttgtcgc
    20281 tgcaccgcct gcactgcctg ttcaatcgcg accgcaaaag ctcgctgatt ggctgcacca
    20341 tgacttttta tcaccgtgcc gcgcaatcct aacagacagg cgccgttata ctggtcgggg
    20401 ttgaggtgac tgaatcgcct cgtcaggctc ttttgtagcc aacgctttaa taacagtagc
    20461 caccacgacc gttttttccc ttcaccctga gatttcagca gagaaaggaa catcctgaca
    20521 acaccttcca tcgtctttaa tgtgacattt cctgtaaagc cgtcacaaac cagcacatct
    20581 gtcttgccag ttaacaactc attggcttca agatagccga tataattgat agaagggatt
    20641 gttttaagca ccgctgaggc atcccgaata ctgtcgagac cctttacttc ttcttcacca
    20701 atattgagca acgccacgcg aggattagga atttccacca cctcttcagc cagaactgag
    20761 cccataatgg caaattgcac caacattgta ctgtcacaat cgacgttggc ccctaaatcg
    20821 aggaccaccg ttttgccctt ttgctgatgc ggtaataccg tcaccagcgc cggacgctca
    20881 atcccctcca ggggcttgag taataatttt gccagcccca ttagcgcccc ggtattaccg
    20941 gcactgacac aggcttgcgc tcgaccttct ttcaccagct ccagggccac gcgcattgaa
    21001 ctcccacgac tggcgcggat agcttgcgaa ggccgggcat cactggcgat aactgactgc
    21061 gcaggaataa tctgcagacg cgaacgttgt tcaaagtcag ctttagcaag taatggcgtg
    21121 atggcgtcgg gattgccgac taaaagaaga gtgagttgcg aattagaatt cagtgcctgc
    21181 aatgctgcag gcactgtcac ggaagggcca aaatcccctc ccatgacatc taacgccagg
    21241 gttagacgtg tcaaggtatc gtcgccgccc ggtttggtct ttccccagtt gcctggggaa
    21301 aatcctcact aagcttcatc acgcagacgc gtaattactt agcgatgacc ttgcggccgc
    21361 ggtagtaacc gtcggcagtg atgtggtgac gcaggtgttt ttcaccagaa gttttgtcta
    21421 cagacaggct ggtgactgcg gtcagcgcgt catgggaacg acgcatgcca cgtttggaac
    21481 gggttggttt attctgttgt acggccatgg accttactcc tcaattacgg tttatccccg
    21541 atccaacggg gagcaccaat tacttacgct ttaagctggc taatacggca aatgggtttg
    21601 gcttttgcgc ttcttcaggc agttcaccaa agaccatgtc cgcttcggac acttcacagt
    21661 gttcagaatc atgcaccgga actaccggca aggcgaggat gatttcatct tcaaccattg
    21721 caagcagatc gatttcaccg aattcgttaa cctcaatcgg ttcatacgct tccggcagtg
    21781 cttcagcctg ttcgtctgaa cgcacaggac taaaacaata cgttgtgtag acctgatgag
    21841 taaacggctt cccgcaacgc tgacactcga gcgttaccgt caccttcgca tcgccgttta
    21901 acactgcgag acgttggtta tcgatagcga acgacatgga gcattccaca tcactgtcca
    21961 cactgactac ggattcggcg acgcgctcaa cctgatcagg agtatagata ccctggtaat
    22021 caaggcgttt ttgagccgta cgaaccggat cgagagtcag gggtaatttt accttttgca
    22081 tagggcgcgc atattaactt tgtaacgtca tagagtcaaa gaaaaaggca gcctgtggtt
    22141 gccttttgcc aataattcgc acacattgcg ggttactgct ttattttcgt tcagtgctga
    22201 taacgaacat caacctgcaa aacgaagcgc atagtttaaa atggctatca tcaatacgct
    22261 atatctgatg gaaaaaaata tgcctgaact tattttagcc tccacctcgc cctggcgtcg
    22321 cgctcttctg gaaaaactgc aaatctcttt tgaatgtgca gcacccgagg tcgacgaaac
    22381 tccacgcagc gacgaatcac cgcgacagtt ggtgcttcga ctggcacaag aaaaagcgca
    22441 atctctggcg tcacgttatc cggatcattt aattattggt tcagaccagg tatgtgttct
    22501 tgatggcgaa atcaccggta aaccgttaac ggaagaaaat gcccgtctgc aattacgcaa
    22561 agccagcggc aatatcgtca ccttctatac tggactggcg ttgtttaatt cggcgaatgg
    22621 gcatctacaa acagaagtgg agccttttga cgtccatttc cgtcacctga gcgaggcgga
    22681 gattgataat tacgtgcgta aagagcatcc cctgcactgc gcgggtagct ttaagagtga
    22741 aggatttggc attacgctgt ttgagcgttt agaggggcgt gatcctaaca cgctggttgg
    22801 tttaccgcta atcgcgctgt gtcagatgtt acgtcgggaa ggaaaaaacc cgctgatggg
    22861 atagtttttt gcgccggatg cggttacgtc gcatccggca atcggtgctg gcggcctgat
    22921 gcggcataaa cgccttatca ggccaaccgc ccattatcat gcttatatgc tcgtattagc
    22981 gcgcgttacg cagtttttgc aaacaacgct tcaaaccatc atccatcggc gcttcgatac
    23041 gcatcacctc accggtcccc ggatgggtaa acttcaacgc tgcggcgtgc aggaacagac
    23101 gatttaatcc cgtgcctgct tcagtgagct gtctgtcaaa ttcacggtca ccgtagcgat
    23161 cgtcaaaggc aatcggatga cccgcatatt gtgtatgcac acggatctga tgagtacgcc
    23221 ctgttaccgg gctacaacgc accagggtgg caaatgcata gcgctcttcc actttaaagc
    23281 gtgtttccga cggtttgcct tcctgactca cacgcacgat acgttcgccg ctttgcagaa
    23341 tatttttcag taacggcgct tgaacgctct tcacatgcga ctgccactga ccgcgcacca
    23401 gcgccaggta atctttttgc atcccttttt cacgtaattg ctcatgcaga gaacgcaacg
    23461 ccgagcgttt tttcgctacc agcaacacac ctgaggtgtc ccggtcaaga cgatgaacca
    23521 gttcaaggaa ccgcgcttcc gggcgcaacg cccgcaaacc ttcgataacg ccgaagctta
    23581 aaccactacc gccatgtacc gccgtaccgg aaggtttatt cagcaccagg atatggtcat
    23641 cttcatataa gatgacgtcc gccagcgccg ccaccttttg cagatgtggc gaaaccgcct
    23701 cttcttcccg ttcagcaacg cgaaccggtg ggatacgcac ctcatcaccc gcttcgagtt
    23761 tatattcagg cttaatacgt tttttgttca cccgcacttc gcctttacgc aaaatacggt
    23821 aaatcatact ttttggtaca cctttcaatt gggtacgcaa aaagttatcg atacgttgcc
    23881 ccgcttcgtc agcggtgata gcaacaattt ttacggatgg agtctctgtt ttcatggtgg
    23941 gcgattctaa ttagccaaca ggattcgcgc cactcatttt tctatgctta tatttagttt
    24001 tgcaccttat tacttcacta catgatcact ttattgatgg ttattaaacc aatcaccagc
    24061 aagaagtgaa aaaactgtga gtaagcgggt gataaatggt aaaagtcatc ttgctataac
    24121 aaggcttgca gtggaataat gaggccgttt ccgtgtccat ccttgttaaa acaagaaatt
    24181 ttacggaata acccattttg cccgaccgat catccacgca gcaatggcgt aagacgtatt
    24241 gatctttcag gcagttagcg ggctgcgggt tgcagtcctt accggtagat ggaaatattt
    24301 ctggagagta atacccagtc tgtttctttg ataattgcgc tgtttttccg catgaaaaac
    24361 gggcaaccga cactctgcgc ctctttgagc tgacgataac cgtgaggttg gcgacgcgac
    24421 tagacacgag gccatcggtt cacacccgga aaggcgttac tttgcccgca gcttagtcgt
    24481 caatgtaaga ataatgagta agttacgatg aaaagaatgt taatcaacgc aactcagcag
    24541 gaagagttgc gcgttgccct tgtagatggg cagcgtctgt atgacctgga tatcgaaagt
    24601 ccagggcacg agcagaaaaa ggcaaacatc tacaaaggta aaatcacccg cattgaaccg
    24661 agtctggaag ctgcttttgt tgattacggc gctgaacgtc acggtttcct cccactaaaa
    24721 gaaattgccc gcgaatattt ccctgctaac tacagtgctc atggtcgtcc caacattaaa
    24781 gatgtgttgc gtgaaggtca ggaagtcatt gttcagatcg ataaagaaga gcgcggcaac
    24841 aaaggcgcgg cattaaccac ctttatcagt ctggcgggta gctatctggt tctgatgccg
    24901 aacaacccgc gcgcgggtgg tatttctcgt cgtatcgaag gcgacgaccg taccgaatta
    24961 aaagaagcac tggcaagcct tgaactgccg gaaggcatgg ggcttatcgt gcgcaccgct
    25021 ggcgtcggca aatctgctga ggcgctgcaa tgggatttaa gcttccgtct gaaacactgg
    25081 gaagccatca aaaaagccgc tgaaagccgc ccggctccgt tcctgattca tcaggagagc
    25141 aacgtaatcg ttcgcgcatt ccgcgattac ttacgccagg acatcggcga aatccttatc
    25201 gataacccga aagtgctcga actggcacgt cagcatatcg ctgcattagg ccgcccggat
    25261 ttcagcagca aaatcaaact gtacaccggc gagatcccgc tgttcagcca ctaccagatc
    25321 gagtcgcaga tcgagtccgc cttccagcgt gaagttcgtc tgccatccgg tggttccatt
    25381 gttatcgaca gcaccgaagc gttaacggcc atcgacatca actccgcacg cgcgacccgc
    25441 ggcggcgata tcgaagaaac cgcgtttaac accaacctcg aagctgccga tgagattgct
    25501 cgtcagttgc gcctgcgtga cctcggcggc ctgattgtta tcgacttcat cgacatgacg
    25561 ccagtacgcc accagcgtgc ggtagaaaac cgtctgcgtg aagcggtgcg tcaggaccgg
    25621 gcgcgtattc aaatcagcca tatttctcgc tttggcctgc tggaaatgtc ccgtcagcgc
    25681 ctgagcccat cactgggtga atccagccat cacgtctgcc cgcgctgctc cggtaccggt
    25741 accgttcgtg acaacgaatc gctgtcgctc tctattctgc gtctgatcga agaagaagcg
    25801 ctgaaagaga acacccagga agttcacgcc attgttcctg tgccaattgc ttcttacctg
    25861 ctgaatgaaa aacgttctgc ggtaaatgcg attgaaactc gtcaggacgg cgtacgctgt
    25921 gtgattgtgc caaacgatca gatggaaacc ccgcactacc atgtgctgcg cgtgcgcaaa
    25981 ggggaagaaa ccccaacctt aagctacatg ctgccgaagc tgcatgaaga agcgatggcg
    26041 ctgccgtctg aagaagagtt cgctgaacgt aagcgtccgg aacaacctgc gctggcaacc
    26101 tttgccatgc cggatgtgcc gccagcacca acgccagctg aacctgccgc gcctgtcgta
    26161 gccccagcac ctaaatctgc accggcaaca ccagccgctc ctgcccaacc tgggctgttg
    26221 agccgcttct tcggcgcact gaaagcgctg ttcagcggtg gtgaagaaac caaaccgtcc
    26281 gagcaaccaa caccgaaagc agaagcgaaa ccggaacgtc aacaggatcg tcgcaagcct
    26341 cgtcagaaca accgccgtga ccgtaatgag cgccgcgacc ctcgtagtga acgtactgaa
    26401 ggcagcgata atcgcgaaga aaaccgtcgt aatcgtcgcc aggcacagca gcagactgcc
    26461 gagacgcgtg agagccgtca gcaggcagag gtaacggaaa aagcgcgtac caccgacgag
    26521 cagcaaacgc cgcgtcgtga acgtagccgc cgccgtaacg atgataaacg tcaggcgcaa
    26581 caagaagtga aggcgctgaa tgttgaagag caatctgttc aggaaaccga acaggaagaa
    26641 cgtgtacgtc cggttcagcc gcgtcgtaaa cagcgtcagc tcaatcagaa agtgcgttac
    26701 gagcaaagcg tagccgaaga agcggtagtc gcaccggtgg ttgaagaaac tgtcgcagcc
    26761 gaaccaattg ttcaggaagc ggcagcccca cgcacagaat tggtgaaagt tccgctgcca
    26821 gtcgtagcgc aaactgcacc agaacagcaa gaagagaaca atgctgataa ccgtgacaac
    26881 ggtggcatgc cgcgtcgttc tcgccgctcg cctcgtcacc tgcgcgtaag tggtcagcgt
    26941 cgtcgtcgct atcgtgacga gcgttatcca acccagtcgc caatgccgtt gaccgtagcg
    27001 tgcgcgtctc cggaactggc ctctggcaaa gtctggatcc gctatccaat tgtacgtccg
    27061 caagatgtac aggttgaaga gcagcgcgaa caggaagaag tacaagtgca gccgatggtg
    27121 actgaggtcc ctgtcgccgc cgctgccgaa cctgttgtta gcgcgccagt tgttgaagaa
    27181 gtggctgaag tcgtagaagc ccccgttcag gttgccgaac cgcaaccgga agtggttgaa
    27241 acgacgcatc ctgaagtgat tgctgccgcg gtaactgaac agccgcaggt gattaccgag
    27301 tctgatgttg ccgtagccca ggaagttgca gaacacgcag aaccggtggt tgaaccgcag
    27361 gaagagacgg cagatattga agaagttgcc gaaactgctg aggttgtggt tgctgaacct
    27421 gaagttgttg ctcaacctgc cgcgccagtc gtcgctgaag tcacagcaga agttgaaacg
    27481 gtagctgcgg ttgaacctga ggtcaccgtt gagcataacc acgctaccgc gccgatgacg
    27541 cgcgctccgg caccggaata tgttccggaa gcaccgcgtc acagtgactg gcagcgccct
    27601 acttttgcct tcgaaggtaa aggtgccgca ggtggtcata cggcaacgca tcatgcatct
    27661 gccgctcctg cgcgtccgca acctgttgag taatagttag ctcaagtaat caagccctgg
    27721 taactgccag ggctttttta tttcatcttt gagtcaacat attaaaattc atcaaatggc
    27781 atccttgcta accaacaata caaaataggc aaaaaaatgc ccgctccggc gatcccagag
    27841 cgggcagaca aaacataccc agtttcatga tatgttttaa agcgagctta tttgttgagc
    27901 tggaagagcg acaatccctg catatcggta aatgctttat acgatgcctg caatgccgtt
    27961 tgctgcatga tgtaagatga aatagttgca ttccagtcca catcaaccag atcgctcatc
    28021 tgctgcgttt gccctaaagc gcgatcgcta cctaatgaat ccagcgactc cagttcgttc
    28081 agttgcgtgc ctaattccgc gcgaacagtc agcacattgt tcagcgagtt tttcagtccg
    28141 cggttggttt tatccagtgc cgcagcggcg gtttctttat ccgcttcgct atccgcgacc
    28201 ggcgttttca gggctgcgat ggcgctatcc agcatggcaa aaagattggt ttcagaagcg
    28261 ctaccgtctg gttccgctac cgcgttgcta gtaatactgt cgaaaatttt gtcgcccgta
    28321 tgtcctatca ccatcgaacg cgaagcatcg acctgttgtt taatactttc tgctccgcct
    28381 tcgtatttgc catccgcctc gctaaacggt gcggattctg ttttataacc ggcaaaaatg
    28441 tagcgcccgt taccgtcagt ggtgttcgcc agattcagca actggtcacg aagcccctga
    28501 atatccgtag ccagcgaggc ccggtcatcg tcactcaagg tgccattgct ggcgtagaca
    28561 attttttcct gagcattctg tatagcggtt gtgacctggc taagtacact ctcttccagt
    28621 gacacttttt gagtggcgaa agtacgcgcc agcgtgtact ggctgttttg cgcctgtgcc
    28681 tgggagagaa caacagcttg tgatgcagca atgggatcat ctgaagggtt aacgactcgc
    28741 ttacccgtcg acatctgttc gccgtacttc atccattctg cctgagaatt ggtgatgccg
    28801 cgcatgtttt gctggtacat catctgggta ctgaaacgca ttttatctcc ccttagcgaa
    28861 tgttaatcag cgcatcaaaa atcgcgtttg ccgtctgcag aacctgcgca ttcgcgaggt
    28921 aatactgctg aaaacgttgc agatttccgt actcctcatc gagattgaca ccggaaatcg
    28981 actgctgctg attggaaagc tgcgtcacca cattaccttg agtggtgcta ctggttttca
    29041 acgtcgcggt tttattaccg atatcactca ctaacgaggc ataagcgtcg ttaaaggatt
    29101 tcgcaccgcc caccgtttta ctgttgcttt gcagatcgag cagggcctga ccgttgcggt
    29161 tgtcgctatc acccgcatct tctgcgctcg ccatggcgat tttcgcttcg tcggtgatta
    29221 atacatccat gttgacgatg gcgtcactta ccggtttcag cgtgaagctg tcgttaacgg
    29281 caggcgttcc tgtaaacgtc aactccagac catcaaatgc cactttaccg ttggcatccg
    29341 gcgtcaccgt aaaagtggta ttgctggcaa ggcgggtgac ctgccactga ttattatcga
    29401 acgagatttt gtaatctgtc gccagtaccg cggaggtatc agttaccgtt gcaccgatcg
    29461 caacgtcacc tttgtttttc gtgttttgca gaaccgcggg cttaccgata gcaaagaaat
    29521 cttcaccggc atcgccgtta gcatcaaatc cggctttgtg ttgggtgttg aaagcctcgg
    29581 caaatgccag cgccagttgt ccaagcgtat tacgcgtctg gtccagatcc tgagaacgga
    29641 atgtcagaat gccgcccagc gacccggtat tcagtaattt ctccgggatc tcaatattgc
    29701 ctgccgtccc atcaacataa gcgacagtcg tacgagaagg gtcggcgctg gaaggaactg
    29761 ccgcaagttg ccgcgccgta cttccctgaa ccagtgagta gccattggcc atcgtgatgt
    29821 tataagtgcc accatcctga acactgactt ctacgccaac aatctggttt aattcgctca
    29881 ccagttgatc gcgttgatcc agcagattgt taggtgacgc ccctgccccc acgcctgtca
    29941 ggcgggagat ctgatcgttc aggctggcga tttgtttagc gtaattgttg atctgatcaa
    30001 cactggcacc tatcgcgata ttgacctgtt tgtcctggtc gcgcagatat tgatcggtgg
    30061 ttttaaactg attcaccaac ccttctgatt tcccaatcag cgcctggcgc gctgccggat
    30121 cttccgcgtt actcaccagc gtttgcaggc tggtgaagaa atcctgcatc tgtgttgcca
    30181 gcgaagaggt actggtggag agcatattgt cgattttcga catctgctca tagcgggcag
    30241 tcaggccgct actttgcgtc tgcgccgcac gtaactggtt ggtaataaac gcatcatact
    30301 cacgctgcac accagaaacg tagacgccat tgccaaccca gccgccagcg cccaacgtgc
    30361 tattggcctg cgccataata gtggtttggc gggtatatcc ggcaacgtta tagctggaga
    30421 tattattact tgccgtattt aacgccgcct gggccgcgtt cagtccgctc atggcgttat
    30481 tgatcaagct ggacatggag gttccttata agccttcaat tacagagtat tatcggcagc
    30541 gacccgccgg acttgagtta ttcagaacag attatcaatg ttcatgctgt aggttttgct
    30601 caccttgtcg cttatcgatt tcatctgctg aatcatgttg gtgagtttgc gggcatagtg
    30661 aggatcggtg gcatagcccg cgtcctgtag ggcctgcgcc ccctgctccg cactcgcggc
    30721 ggtcgtcacg gcggcgtagc gcgggttacg cgttaacagc ccaacgtaat ccgacaatgc
    30781 ttccagatac gagctgtaga cccgaaactt cgcttttact ttcttcgctt cgccattttc
    30841 atattcagtc gtggtgattt cagtgactgg ccctttccag ttgccagagg ctttgacacc
    30901 aaacaggtta tagctcggct cgccgttttc acggcggatt tgccgttgtc cccagccaga
    30961 ttccagcgcc gcctgagcga ggatcaaatg atgtggcaca ccactttgct ggcttgccag
    31021 ttgggcgggc agcgagagtt gcgcgaggaa tgctttactg tcacccggca gcgaatcatc
    31081 gtagttacgt ggtacggcct tttgcaccag ctgcgaaagc gtctgatttt gataacgcac
    31141 cacggtttcg agcgggaatt ttatcggtgc tgctggcgtg gactcctctg gcaatggttg
    31201 ttctggcgtc atctgtttaa ccatcatctc tgccagcccc agacctttgc ccgccgtcat
    31261 ctgttgggca atctgctggt catacatact ggtatacagg cgagtgtgct cgctgctgaa
    31321 caggccatct tttggtaaag cgtcgcgcat gcttttcaac atcatctgca cgaacatccc
    31381 ttccacctgg cgggccaccg gacggatatt tgccgctgga tcttcgcccg ctttcgcctt
    31441 tagttcgttg agtgattgcg catcccaggc cgcacttgcc agtagtttgc tgtcgctgat
    31501 catcagatga tttccagttt tgcccgcaga catcccgcac tttgcattga ttgcagtatg
    31561 gacatcagat ccatcggcgt agcgcccagc gcattgagcg cacgcaccac gttattgagg
    31621 ctggcgctgg aacgtacgct ttgcagcgaa ccgccgctct ggcgtaaatc gatctgcgtt
    31681 tgtggagtaa ccacagtctg cccaccacca aacggtgtat ctggctggct gacattggcc
    31741 tgacgattaa ctgttactga gagattcccc tgcgctaccg cgcagctgtc gagggtcact
    31801 tcgcgattca tcaccaccga accagtgcgc gagttaatca ctactttagc gtcctgcggg
    31861 gtgacattaa cctgcatatt ctggatatcg gcaaggaaac ggacctggga actgttgcca
    31921 cttggtacgc gcacctgaat agtccgcgca tctaacgcgg tggcgctgcc atatccacgc
    31981 acgcggttga tggtgtcagc gatttgctgc gccatactga aatcttcgtc gttaagttgc
    32041 aaattaaggg tattcccgac gccaaactgg ctgggcaatt cacgttcaat aaccgcacca
    32101 ttggtgatcc gtccaccgtt cagttgattc acctgaacac tgctaccgcc agcggaggcc
    32161 cctgcgccgc caaccagaat attgccctgc gccagcgcat acacctgact gtcaacgccc
    32221 ttaagcggtg tcatcaataa cgtaccgcca cgcagacttt tggcatttcc catggaagaa
    32281 accaccacgt caatggtttg cccctgacgt ccaaacggtg gaagtgacgc tgtcaccata
    32341 accgcagcga cgttttttag ctgcatatta gtgcccgtcg gaacggtaat tcccagctgt
    32401 gagagcatgt tattaagcgt ttgtgtggta aacggcgtct gagttgtctg gtcacctgta
    32461 ccatcaagcc ccaccaccag gccatagcca atcagtgagt tttgccttac cccctgaaca
    32521 ctggtgagat cgcgaatacg ctcagcctga gccgccgtgg taaccagtaa aagaattaat
    32581 gcagagagaa atttaatcac cacagcctca cttacattgg cgacaggtta aggaagaaac
    32641 gctgcaacca gcccatattt tgcgcttcgt taatgtagcc attgcctacg tattcaatgc
    32701 gcgcatctgc cacctgagta gacggtacgg tattgctgcc gctgatagtg cgtggattaa
    32761 ccaccccaga gaagcgaata aattcggtac cctgattaat ggcgatctgt ttttcaccca
    32821 ccacatgcag gttgccgttg accagtacct ggtcaaccgt caccgtcaac gtaccgctaa
    32881 aggtattgct ggcattggcc ccgccttttc cgttgaacgt gttaccaccg gaggcttcga
    32941 catcggcacg agcgttacca aacaacccct gcaaatagcg cggcacagta tcaaagccaa
    33001 aattagtttt accgtcacgg ctggcattcg cagaggagct tttgctggcg ctgacgttct
    33061 cctgcaacac gatagtcagc gtatcgccaa tattgcgtgg tcgacgatct tcaaacagcg
    33121 gttgatagcc atagttaatc ggctgagcag actggaaaat agacccgttg gcgacgggcg
    33181 tcggaccggg aaccggttgt gcactggtcg ccccctgtac cagcggcgtg gagggtatcc
    33241 aggcgcagcc ggttagtgaa agcgccaaca agctggaaat ggcataagta tgcgcagcgt
    33301 ttttttgcat ggctatcatc ttcaaaaatc agtaaaccgg tgaacctgcc caccggttaa
    33361 gccttagagt tgcgtcagtt tttgcagcat ctgatcggtg gtggacaccg ctttactgtt
    33421 gatttcgtaa gcgcgttgca cctgaatcat attgaccagt tcttccgcca cgttgacgtt
    33481 agacgtttca acataccctt gatacagcag tcccgcgccg ttcaggcccg gcgtgctttc
    33541 gttcggtgca ccggaggatt gcgtttcggt gtagaggttt tcgccaatgc tctccagtcc
    33601 ggtgtcattc ataaaggtgg tgagattgag ctgcccaacc tgaaccggag ctgcctggcc
    33661 ttgttgggtt acgctgacca cgccatcacg accgatggtg atacttaacg cattcgccgg
    33721 aatggtgatc gctggctgca cctgaaaacc accggccgtc accagctgcc cgttctgatc
    33781 cacctggaaa gagccgtcac gggtataggc tgatgagcca tctggcaaca tcacctggaa
    33841 aaagccctgc cctttaatcg cgacgtcttt actgttattg gtttgcgaca ggttgccctg
    33901 gctgtgtaaa cgttccgtgg cgacagggcg tacccccgta ccgatttgta atccggatgg
    33961 taaggtggtt tgttcggaag actgtgcccc cggctggcga atggtttgat aaagtagatc
    34021 ttcaaacacc gcgcgctgac gcttaaaacc gttggtacta acgtttgcca ggttgttggc
    34081 aatgacgtcc atattggttt gctgggcgtc aaggcccgtt ttggcgatcc ataatgaact
    34141 gatcataaaa tgtcctgtag tggattagtg acaaagtgca tatgtcttct tgccggatgc
    34201 ggcgtaaacg ccttatccgg cctacaagag ctcgcaaaat cgataaattg cgattgcccc
    34261 catagacccg ataaacttgc gcatagggca acttatactt gtcatgtatc ctttcaatta
    34321 actcatcgac agcagttggt tggcacggcc tgcgttatca tcgacgctgc tgatcacctt
    34381 catctgcatt tcaaaacgcc gtgcgctggc aatcatgtcg ctcattgccg caacggcatt
    34441 gacgttactg ccttccagaa cccccgacat cacacgcaag gttggatctg cctgcagtac
    34501 cggcccacgc gtagcctggc tttctgcgct taaacgaaaa atgccatcgt caccgcgctg
    34561 gacttcgctg cccgtggctt tcaccagctt cagacgcccc actggcgcaa ccgtatttgc
    34621 cggatcgccc ggattcagcg ccgagattgt gccatcggca gcaatagtga tttccgcccc
    34681 ttccggcaca gcaattggcc ccgcctcgcc taccaccgga tgtccctgaa ttgtcagttg
    34741 cccggtggga tcaacctgaa tgctgccatt acgcgtatac ccttcactgc cgtcagcggt
    34801 ctgcacgacc agccaaccat cctgctgcaa cgcaacgtcc agcgggcgcg aggtgtaatc
    34861 catcttgccg ggcgtcatgt ctgcacccgg tgttgacgcc gttaccagcg tgcgcgtggg
    34921 cagtgaaagc ccttccaccg gcactgcgcg caaggcgttt aactgcgcgc gaaaaccggg
    34981 cgtagaggca ttggccagat tactggcggt taccgcctgt tgattcagcg tctggctggc
    35041 tgctcccatc gcggtataaa ttgcgtgatc cattgagcta tcccgtcagc gattagcgta
    35101 agttaaccag cgtattgagg atctggtcct gggttttgat ggtctgggcg ttagactgat
    35161 agttacgctg ggcaacgatc atattgacca gttctttact gagatcgacg ttggacgctt
    35221 ccagcgcacc gttggtcagg gtgccaaagt tgcccgtccc ggctgtcccc aacagcgcca
    35281 cgccagaaga ttgcgtagcg gaccagacgt tgtcgccttc ggatgccaga ccttcgttgt
    35341 tggcaaagtt cgccagtaca atctgcccca gcagttgggt ttgttcgttg gaatagttgc
    35401 cgacaaccgt accgtcatca ttgatttgat aactcaccag atcgcccggt ttgtagccgt
    35461 tctgggtggt tgccacaatg ttgttagcgc cggtattttg ctgcatggag ttgaggaagc
    35521 tcaggctaaa cgtggcggga tctgcgccgt taattgcgcc ggtggtaata tcctttgttg
    35581 gatctgaggt cagaacgcca ttggcattaa acaccagcgt cgttgcaggg ttagctgtgc
    35641 ctgttggatc actgctatcc agggtgtaaa catcccagtt attatccccg gtcttcacaa
    35701 agtagacgct catgtcatga gcattaccct gactatcgaa aacagtcacc gaaccttttt
    35761 tgttatagct atccgcattg ctggcatcaa atgcgttaac agagggaagc gaatcactgg
    35821 aattcaggtt gatctgcatc gacgccgtgg tggtagtttt cgctgccatc agggtattcg
    35881 gaatcgaaat attggtcgga ttcgcccctt gctgaatagt cggcggcgta ccggttgccg
    35941 ggtaacccgt cagctgtaaa ccttgcatat tcaccaggtt acggttttca tccagcttaa
    36001 attgtccgtt acggctgtag aataccgaac cattgctgtc taccagacgg aaaaaaccgt
    36061 tctggctgat agcaacgtcc agaccacgcc cggtgttggt ggtcgtgcca tcggtaaagt
    36121 cctgagtgat accagcaact tttaccccca gtcccacttt cgaaccggca aacatatcgg
    36181 caaaagaggc cgtgcctgat ttaaagccgt aggtggcgga gttggcgata ttgttgccaa
    36241 taacatcgag gttggtggcg gcagcgttta atccgctaac cgcttgagaa aaggccatga
    36301 ctgactcctg aaatgtgaag gcttaaatta tctgccgtac ttcgtcgagg gtagtggtgc
    36361 cgtaagtgcc aagatccagc gtattaccgt tgttgccgcg gatcaccccc tgcaccagag
    36421 caaactgcag cggttgggca accagttgtg taccaccgtt actggcgcta atcgctacat
    36481 tgtaagaacc gttcggcgca gtgctgccgt cagtcaacgt accgtcccag gtgaaactgt
    36541 ggactccggc agtcagttca ccgatatcaa tggtacggac gaccgcgccg tttttatcgg
    36601 tgatggtggc cgtcactttg tctgctgcct gttgcaactc aacaccaaac ggcgtggtcg
    36661 tggtcacagc cccttcttca ctgccggttc ccgcaagaac tgtggtaccg gggatcatca
    36721 cgccgtgacc gataaggtta ctggcctgta acgactgact gttatcaatc tgtccggaaa
    36781 tagatccgag cgtggtattg agtttttcaa tcccactgac cgtgctgatt tgtgccaatt
    36841 gcgacgtcag ctcgttgttt tccattggat tggtcgggtc ctggtttttc agctgcgcca
    36901 ccaacaaagt cagaaaactg ctttgtaaat ctgcggcgtt gctgcccgtg agcgaactac
    36961 tgctggtggt actgacgccg gtattcgtcg gatcggtggt ggttaccgca atagacatag
    37021 ctttctcctt tattgaccga gcgtaagggt tttcagcatc atgcttttca ccgtgttgag
    37081 cacttcaaca ttggcctgat aactgcgtga cgccgacatg gtgttaacca tctccccgac
    37141 gacatcaacg tttggcattt tcacgtagcc ctttgcatcc gccagcggat tacccggttc
    37201 ataaaccagt ttgtccgggg cctgactttc tataacatcg gcaaccttta cgccgcctgt
    37261 cgcagcacct ggtgcagcgt taacctggaa taccacctgt tttgcccgat atggctgtcc
    37321 atcgggaccg gtcacgctat cagcattcgc cagattactg gccgccacgt tcagacgctg
    37381 ggactgggca gttaacgccg acccggcgat atcaaaaata ttcagcagtg ccatccgtta
    37441 atttccgctc tgtaaaacgt tcatcatgcc tttaatttgc ccgctcaacg cgctaaggct
    37501 catctggtat tgcaggctgt tatcggcaaa ctgggtgcgt tcgcgatcca tatcgacagt
    37561 attaccgtca agcgaaggct ggtccggaat acggtattgc agttctgcgg aaggaggcgt
    37621 cagcgcctgc gccggaatgt gttgcgttga ggtcatcgtc agagcaacca cactggttgc
    37681 atcccgtcca cgttgcatga cttttttaag ttcactggca aaatcgatat cgcgcgcctg
    37741 ataaccaggg gtatcggcat tggcgatgtt tgctgccagc acttcctgac gctgggcgcg
    37801 cagattgagc gcctcttgtt gaaaacgtaa ggcggcgtcg agcttatcga gcatatctcc
    37861 tccgcaggta tcaaaattct gccatcagct taaatgcctt tacgcgcgcg ttatcggcgg
    37921 aataaacgca aaatgggtcg ctatttatgc cgttgatggt cattgcggac aggtacaatt
    37981 cacgttgtag aaatggctgg gggcgaaaat gctgacaata aaacgtagcg tggcgatcat
    38041 cgcgatactc ttcagtccgt taagtacggc gagcaatctc acatcgcaat tgcacaactt
    38101 ttttagcgcc caactcgcgg gggtaagtga tgaggttcgt gtttctattc gtacagcgcc
    38161 caatctgcta ccgccgtgcg agcagccatt gctttcgatg agcaataatt cccgcctgtg
    38221 gggcaatgtg aatgtgttgg cacgctgcgg taacgacaaa cgatatttac aggttaatgt
    38281 acaggccaca ggaaattatg tggttgccgc gatgcccatt gtgcgtggag gaaagctgga
    38341 agctggcaat gtcaaactga aacgcggacg gctggatacc ttgccaccgc gtacggtgct
    38401 ggatatcaat caacttgttg atgccgttag cctgcgcgat ctatcacccg atcaacctat
    38461 ccagttaacc cactttcgcc aggcatggcg ggtaaaagcg ggacaacgcg tcaacgttat
    38521 cgccagcggt gatgggttta gcgccaacgc agaaggtcag gcgctgaaca atgcagccgt
    38581 cgcacagaat gcgcgggtgc gcatgatatc gggacaagtg gtcagcggcg ttgttgatgc
    38641 agatgggaat attcttataa acctgtaagc tgttaaagat tacccgtccc ttgccgataa
    38701 ataagcaaca catgataaaa gcgccctcaa tgaggaataa accatgagta ttgatcgcac
    38761 ttcgcctctg aagccagtaa gcaccgttca accgcgcgaa accactgacg cgccggtaac
    38821 aaacacccga gcggcaaaaa caacagcctc caccagcacc agtgtgacgt taagcgacgc
    38881 gcaagcaaaa ctgatgcaac ccggcagcag tgatatcaat cttgaacgtg tcgaagcgtt
    38941 aaagctggcg attcgtaacg gtgaactaaa aatggacact ggcaaaattg ccgatgcgct
    39001 gatcaacgaa gcgcagcaag acttgcagag taattgatcg tatgacgcgt cttgcagaga
    39061 tcctcgacca gatgtccgct gtgcttaacg atctcaaaac ggtaatggat caagagcagc
    39121 aacatctctc tatggggcag atcaacggca gccagttgca atggattaca gaacaaaaaa
    39181 gctcactgct ggcgacgctg gattacctcg aacagttacg caggaaagaa cccaatacag
    39241 caaatagcgt tgatattagt caacgctggc aggaaattgc tgtgaaaacg cagcaactac
    39301 gccaaatgaa tcaacataac ggctggttac tggaaggaca gattgagcgc aatcaacagg
    39361 cgctggaaat gttgaaaccg catcaggaac cgacgctgta tggggcgaac ggtcagacct
    39421 caacccccta tcgcggcagt aaaaagattt cgatctgaag attatctccg gcctgcactg
    39481 caggccggaa tgtatcgtta caccgtccgg cgggcaaatt ctttaacttt gaagcccagt
    39541 actgccagtg cagcgaagta cgcggcaatc cccgccagca cgaccgccat taaacgcagt
    39601 aaacgccagg gcatggtacc caatgaccac tccggcatga tatgtaacat acctaaaagc
    39661 acgccagaca tcaccagtac cgccaccacc agacgcaaca gaaacgccat ccagccgggt
    39721 tgcggagtaa agattttctg cttacgcaac tgccagtaaa gcagcgaagc attcagacac
    39781 gccgccagac caatagaaag tgacagcccg gcatgtttca acggaccaat aaacgccagg
    39841 ttcatcaatt gcgttaaaat cagcgtaacg atggcaattt tcactggcgt tttaatgtcc
    39901 tggcgggaat aaaagccagg agccaacact ttcactacaa tcaggccaat caaacccacc
    39961 gagtaggcaa ttaacgcccg ctgggtcatc agcgcatcaa aggcggtaaa tttaccgtac
    40021 tggaacagcg aaacggttaa cggaccggaa agaatgccca acgcaaccgc acttggcagc
    40081 gccaacagga aacaaagacg cagcccccag tccatcaaac ggttgtattc atcatgattg
    40141 ccactggcaa aacttttcga cagcgacggt agcaaaatgg tgccaagcgc cacgcccagc
    40201 acaccggacg gaaactccat taagcggtcg gcgtaataca tccacgacac cgaaccggaa
    40261 gcaagaaacg aggcaaaaat ggtgttgatg attaaggaga tctggctcac agagacgcca
    40321 aggattgccg gtcccatctg tttcaccaca cgcattgctc cggcatcgtg gaagttaatg
    40381 cgtggcaaaa ccagcatgcc gatcttcttc agatgaggta gctgatacac cagctgcagg
    40441 atgccgccga ccgtaacagc ccaggccagc gccagcaccg gtggattaaa gtacggcgcg
    40501 gcaaacagcg caaaaccaat catgctgata ttgagcaatg tcggggcaaa cgccggaatt
    40561 gagaagcggt tccaggtatt cagaatcgct cccaccagcg acgccaggga gatcagcaag
    40621 atatagggaa aggttatctt tagtagctgg ctggtcaggg caaatttgtc ggcagtgtca
    40681 gcgaagcctg gcgcggtcac catgatcacc cacggtgcag cgagcatgcc agcgaccgtc
    40741 acaaccgcca gcgcaagtgt cagcaggcca gaaacataag agacaaagac ccgcgtggcg
    40801 tcttcaccct gcttgctttt atattctgcc agaatcggta caaatgcctg ggaaaatgcc
    40861 ccttcggcaa agatacggcg taacaagtta ggaagtttaa aagcgacgaa aaaggcgtcg
    40921 gttgccatcc ctgcgccaaa gattctggcg acaattgcgt ctcgtgcgaa gccaagcaca
    40981 cgcgaaaaca tggtcatcga gctgacggcg gccagcgatt ttaataaatt catcggtgtt
    41041 ctaatccaga cccacgggca aaacgcctgc aaggcaggcg ctgaaagagg cgaatagtct
    41101 acctggatta tggtgaattg ctaccgccag atgttacagg gtttattcac tcatcgcatc
    41161 gcgccagatc ttgtcaacga tacgttgcgc cagcacggcc tgttcgccgg ctgtttgcgg
    41221 aactgtctga ttttgcacgc attcaatgaa gtgccgcgca cagtcgacaa atccacgttg
    41281 ctcaagcgta ctctgccaac caggaatcgg tttatgcact acgccctgcc cgcgctcctc
    41341 acgccattcg cgcatatccg taatgtcgat cagcgcacca tcagtcacgg cctgcacggt
    41401 ttcacgctga cttccggccc ggcgatgcat acaggtggtg atctgcaaag gaccagccga
    41461 aaaatggtgc tcggcaaaca gcatttcgcc ggactcattg gtcagcaacg taccgctttc
    41521 gagagttgca ttgccgccag acaaccacag cgcggtatca accacatgca aataatcatc
    41581 cagcaatgtg aaataaagat cgtgtggccc gacgctattg gtacgatgtt tatccattct
    41641 tagcgaggac gcggtggcga gttgcgtttt taactcaccg tagagtggtg cgaaacgacg
    41701 gttaaaaccg accatcaacg tcagtttttt ccgcgccgcc agttccacca gccgttcagc
    41761 atcgcgcaga ttttctgcca gcggtttatc gacacagaca tgtacccccg cattgagtaa
    41821 cgtactgacc acgccaaagt ggctggcggt gctggaatgc acaaaaaccg catcgcaact
    41881 ggcggcaagg ctggataacg aatcagcata aggaatgcgc cagctgtcac aaattggcag
    41941 ggctttggcg cgcgtaggcg accaggcacc ttgtaacgtc cagtcagacg ctgccgccag
    42001 caccggtaac cacgcttttt gcgcgatgcc gcctaacccc actacgccga tacgtaattt
    42061 tttcacttta atctcccaga tgggccagca acgaatcaag acgctgtttc agttctgcca
    42121 cttcgatttc cagggcttcg acgcgggcct gtaaatcacc gtcaaccgcg ttcgacatat
    42181 ccgttaccgc cggcggattc tcaacctcac cactgaaaag atgcatgtag cggctttcgc
    42241 gtttacccgg ttcgcgggcc agacgcacca caaaaggacc atcttcgcga ttcgccagtt
    42301 gttccagcgt cgactccact tccgccatat cgctgaattc atacattcgc gcggcgcggc
    42361 tgcgcagttc acccggcgtc tgggcaccac gcaataacag cgtggtgatt aacgccactt
    42421 ctgcggcgct cagtttcaga tcgccaaatt ctgaattaca aaaacgttgc tcatatttgg
    42481 tgacccgatt accaaaaccg ctcaccgtgc gtagataatg acgtttgacc agattatcca
    42541 gctgttcctg cacttcagat tcactcagat tcataaccgg ttcacggttc gttttctgat
    42601 tacaggccgt gactacacca tttacggaga gcgggtattg ctccggcgtg gtcacctgtt
    42661 tttccagcaa gcaaccaatc acgcgggctt ccagggcggt cagttgatat ttcatgagat
    42721 tctccttagc ggccgggcgt ccagtctggg gtagttaatg ccgtcagtac gtgatcgcgc
    42781 cattgtccat caatcaacag atagtctttc gcatagcctt ctttttcaaa acccagtcgc
    42841 gccagtaaat caccgctgcg tttattgtgc ggcatataat tagccataat gcgatgaata
    42901 tgttgggtgc gctgcatata acgaatggct gcgctcagag cttcaaacat gagtcctttg
    42961 ccctgccatt tttgcccaat cgaataaccg agatagcagg catgaaaaga gccgcgaaca
    43021 acattggaaa aattggcaac gccaataatc tctttttcgt ccgggtcgaa taagccaaag
    43081 tagaaagctg aaccttgttt atgaaattcg ttaatcatcc ctagcctggc ctgccagcct
    43141 gatggataac agtggctttc gtcgcgcact ggctcccagg gcttgaggaa atggcgattc
    43201 tctgcgtaat aatccgccag acgccaggca tcacgatcat gcaccagacg cacgaccagt
    43261 cggtctgtgg ttaagcgcac ttttggcacg ttactgcgat agccaaacat tctataccta
    43321 ctccttcccg taacgtcttt aatacgctgt aagtattact atacctgcgc aaccagaccc
    43381 tgtgaaaagt ccagaatgcc attttctgca ttattcacat atttgataaa aactctctat
    43441 caaagcgacg ttttgataaa aaaatattgt ccccgaagtg atgggaaaag tcttagcggc
    43501 aatgcagaat agaaagtgct catcttttat ttcccgggag gggaaatgtc ccgcgtgtcg
    43561 caggcgagga acctgggtaa atatttcctg ctcatcgata atatgctggt cgtgctgggg
    43621 ttctttgttg tcttcccgct gatctctatc cgcttcgttg atcaaatggg ctgggccgcc
    43681 gtcatggtcg gtattgccct cggtctacgc cagtttattc agcaaggtct gggtattttc
    43741 ggcggcgcaa ttgccgaccg ctttggtgcc aaaccgatga ttgtcaccgg tatgctgatg
    43801 cgtgccgccg gattcgccac aatgggtatc gcccacgaac cgtggctact gtggttttca
    43861 tgcctgcttt cgggactcgg cggcacgttg tttgatcctc cgcgttcggc gctggtggtg
    43921 aaactaatcc gtccacaaca gcgtggtcgt tttttctcgc tgttgatgat gcaggacagt
    43981 gccggtgcgg tcattggcgc attgttgggg agctggctgt tgcaatacga ctttcgcctg
    44041 gtctgcgcca caggggcagt tttgtttgtg ctgtgtgcgg cgttcaatgc gtggttgtta
    44101 ccagcatgga aactctccac cgtacgcacg cccgttcgcg aaggcatgac ccgcgtgatg
    44161 cgcgacaagc gttttgtcac ctatgtcctg acgctggcgg gttactacat gctggctgta
    44221 caagtgatgc tgatgctgcc aattatggtc aacgacgtgg ctggcgcgcc ctctgccgtt
    44281 aaatggatgt atgccattga agcgtgtctg tcgttaacgt tgctctaccc tatcgcccgc
    44341 tggagtgaaa agcattttcg tctggaacac cggttaatgg ctgggctgtt gataatgtca
    44401 ttaagcatga tgccagtggg catggtcagc ggcctgcaac aacttttcac cctgatttgt
    44461 ctgttttata tcgggtcgat cattgccgag cctgcgcgtg aaaccttaag tgcttcgctg
    44521 gcagacgcaa gagctcgcgg cagctatatg ggatttagcc gtctgggtct ggcgattggc
    44581 ggcgctattg gttatatcgg tggcggctgg ctgtttgacc tgggcaaatc ggcgcaccag
    44641 ccagagcttc cgtggatgat gctgggcatt attggcatct tcactttcct tgcgctgggt
    44701 tggcagttta gccagaaacg cgccgcgcgt cgtttgcttg aacgcgacgc ctgatttgat
    44761 actcccccct gactcctcca tactgaaaga gaactgacag ccaaatggag gagtcacgtg
    44821 aagctataca tttacgatca ctgcccttac tgcctcaaag cccgcatgat tttcggcctg
    44881 aaaaatatcc ccgtcgaatt acatgttctg ctcaacgacg acgcagaaac acccacccgg
    44941 atggtcggtc aaaaacaggt tcccattctg caaaaagatg acagccgcta tatgccagaa
    45001 agcatggaca tcgttcacta tgtcgataaa ctcgacggca aaccgttact gaccggcaaa
    45061 cgttcccctg ccattgaaga gtggctgcgc aaggtcaatg gctacgccaa caaactgctg
    45121 ttgccgcgtt ttgccaaatc ggcatttgat gagttttcta ctcctgccgc gcgcaaatat
    45181 ttcgtcgaca agaaagaggc cagcgcgggt aattttgccg acctgctggc ccactctgac
    45241 ggtctgatta agaatatcag cgatgattta cgtgcgctgg acaaactgat cgtcaaaccg
    45301 aacgccgtga atggcgaact ttcggaagat gatattcagc tatttccgct cctgcgtaat
    45361 ctgacgctag tagccggaat caactggcca agccgcgttg ctgattaccg cgataatatg
    45421 gcgaaacaga cacaaatcaa tttgttatca tcaatggcga tttaatcctg acccgtcgcg
    45481 gcagcctgta ttcgcgggtt gccgccgttt tcagtttttt ctgctggcgc gttatcgctg
    45541 gtgacacatg ctgcgttgtg tcaggatatt gacgcagatt tcatgtcgag gactaccatg
    45601 aacaagtttt tatttgccgc tgcattgatc gtcagtggcc tgctcgttgg ctgtaatcaa
    45661 ctcacccaat acaccatcac cgaacaagaa attaaccagt cgcttgcgaa acataataat
    45721 ttctcaaaag atatcggttt acccggcgtg gctgacgccc atatcgttct gacaaacctg
    45781 accagccaaa ttggtcgcga agagccgaat aaagttaccc taaccggaga cgccaatctg
    45841 gacatgaact ccctgttcgg tagccagaaa gcgaccatga aactgaagct gaaagcgctg
    45901 cccgtgtttg ataaagaaaa aggcgcgatc ttcctgaaag agatggaagt ggtcgatgcg
    45961 acggtacaac cggaaaaaat gcaaacggtg atgcaaacgt tgcttcccta tttaaaccag
    46021 gcattacgca attactttaa ccagcaacct gcttacgtcc tgcgcgaaga tggcagccag
    46081 ggcgaagcaa tggcgaagaa actggcgaaa ggcattgaag tgaagccagg cgaaattgtc
    46141 attccgttta ctgattaatc acgagggcgc attcgcgccc tttatttttc gtgcaaagga
    46201 aaacgtttcc gcttatcctt tgtgtccggc aaaaacatcc cttcagccgg agcatagaga
    46261 ttaatgactg caccatccca ggttttaaag atccgccgcc cagacgactg gcaccttcac
    46321 ctccgcgatg gcgacatgtt aaaaactgtc gtgccgtata ccagcgaaat ttatggacgg
    46381 gctatcgtaa tgcccaatct ggctccgccc gtgaccaccg tagaggctgc cgtggcgtat
    46441 cgccagcgta ttcttgacgc cgtacctgcc gggcacgatt tcaccccgct gatgacctgt
    46501 tatttaacag attcgctgga tcctaatgag ctggagcgcg gatttaacga aggcgtgttc
    46561 accgctgcaa aactttatcc ggcaaatgca accactaact ccagccacgg cgttacgtca
    46621 gttgacgcaa tcatgccggt acttgagcgc atggaaaaaa tcggtatgcc gctactggtg
    46681 catggtgaag taacacatgc agatatcgac atttttgatc gtgaagcgcg ctttatagaa
    46741 agcgtgatgg aaccgctgcg ccagcgcctg accgcgctga aagtcgtttt tgagcatatc
    46801 accaccaaag acgctgccga ctatgtccgt gacggaaatg aacggctggc tgccaccatc
    46861 actccgcagc atctgatgtt taaccgcaac catatgctgg ttggtggtgt gcgtccgcac
    46921 ctgtattgtc tacccatcct caaacgcaat atccaccaac aggcattgcg tgaactggtc
    46981 gccagcggtt ttaatcgtgt attcctcgga acggattctg cgccacatgc acgtcatcgc
    47041 aaagagagca gctgcggctg cgcgggctgt ttcaacgccc caaccgcgct gggcagttac
    47101 gctaccgtct ttgaagagat gaatgctttg cagcactttg aagcattctg ttctgtaaac
    47161 ggcccgcagt tctatggctt gccggtcaac gacacattca tcgaactggt acgtgaagag
    47221 caacaggttg ctgaaagcat cgcactgact gatgacacgc tggtgccatt cctcgccgga
    47281 gaaacggtac gctggtccgt taaataataa aaatcgtagc ttcctgttgt cattaggtta
    47341 ttttacctgt ataaataacc agtatattca acagggggct attatgcgaa ttgaagtcac
    47401 catagcgaaa acttctccat tgccagctgg ggctattgac gccctggctg gcgaactttc
    47461 ccgccgtatt cagtatgcgt ttcctgataa tgaaggccac gtatcggtac gttatgccgc
    47521 agcaaataat ttatcggtta ttggcgcgac aaaagaagat aaacagcgca ttagcgaaat
    47581 tctccaggag acgtgggaaa gcgccgatga ctggtttgtc agcgaataat atgcagtgat
    47641 ttttgttttt gccgggtcgc cccggctttt ttattttact tgcgaattgt gagtacaaaa
    47701 tttctacact tactcaaaat aattgcac
//
LOCUS       DAPOXO010000031        47513 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPOXO010000031 DAPOXO010000000
VERSION     DAPOXO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47513
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.031"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            287..1504
                     /gene="alaA"
                     /locus_tag="ROH59_002146"
     CDS             287..1504
                     /gene="alaA"
                     /locus_tag="ROH59_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HDX4804626.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSGYHQL"
     gene            1588..2187
                     /gene="yfbR"
                     /locus_tag="ROH59_002147"
     CDS             1588..2187
                     /gene="yfbR"
                     /locus_tag="ROH59_002147"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HDX4804627.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMVPEELQDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL"
     gene            complement(2246..4078)
                     /locus_tag="ROH59_002148"
     CDS             complement(2246..4078)
                     /locus_tag="ROH59_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDX4804628.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPI
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(4165..4815)
                     /gene="hxpA"
                     /locus_tag="ROH59_002149"
     CDS             complement(4165..4815)
                     /gene="hxpA"
                     /locus_tag="ROH59_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpA"
                     /protein_id="HDX4804629.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLSPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEHIEATETEGITALPGAIALLNHLNKAGIPW
                     AIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            complement(4826..5320)
                     /locus_tag="ROH59_002150"
     CDS             complement(4826..5320)
                     /locus_tag="ROH59_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HDX4804630.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(5403..5858)
                     /locus_tag="ROH59_002151"
     CDS             complement(5403..5858)
                     /locus_tag="ROH59_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HDX4804631.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            6196..7398
                     /gene="ackA"
                     /locus_tag="ROH59_002152"
     CDS             6196..7398
                     /gene="ackA"
                     /locus_tag="ROH59_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDX4804632.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            7473..9617
                     /gene="pta"
                     /locus_tag="ROH59_002153"
     CDS             7473..9617
                     /gene="pta"
                     /locus_tag="ROH59_002153"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDX4804633.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIIANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSTKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIDSLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRENYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            9807..11327
                     /gene="yfcC"
                     /locus_tag="ROH59_002154"
     CDS             9807..11327
                     /gene="yfcC"
                     /locus_tag="ROH59_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDX4804634.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAIFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(11360..11902)
                     /gene="yfcD"
                     /locus_tag="ROH59_002155"
     CDS             complement(11360..11902)
                     /gene="yfcD"
                     /locus_tag="ROH59_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HDX4804635.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(11960..12511)
                     /gene="yfcE"
                     /locus_tag="ROH59_002156"
     CDS             complement(11960..12511)
                     /gene="yfcE"
                     /locus_tag="ROH59_002156"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDX4804636.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            complement(12567..13211)
                     /gene="yfcF"
                     /locus_tag="ROH59_002157"
     CDS             complement(12567..13211)
                     /gene="yfcF"
                     /locus_tag="ROH59_002157"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HDX4804637.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLALGQPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            13347..13994
                     /gene="yfcG"
                     /locus_tag="ROH59_002158"
     CDS             13347..13994
                     /gene="yfcG"
                     /locus_tag="ROH59_002158"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HDX4804638.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAGLDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLNHETRERAVTLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQHGDERSDS"
     gene            14051..14413
                     /gene="folX"
                     /locus_tag="ROH59_002159"
     CDS             14051..14413
                     /gene="folX"
                     /locus_tag="ROH59_002159"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HDX4804639.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYTDSVSMTLSWQR"
     gene            14434..15327
                     /locus_tag="ROH59_002160"
     CDS             14434..15327
                     /locus_tag="ROH59_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HDX4804640.1"
                     /translation="MNIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPR
                     VTLWQGLAEQSNLNGVDAVINLAGEPIADKRWTHERKERLCQSRWNTTQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRFGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPVRNEQFAHALGHALHRPTILRVPATAIRLLMGESSVLVLGGQRALPKKL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(15486..16259)
                     /gene="hisP"
                     /locus_tag="ROH59_002161"
     CDS             complement(15486..16259)
                     /gene="hisP"
                     /locus_tag="ROH59_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HDX4804641.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSDGSIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKGSLK"
     gene            complement(16267..16983)
                     /locus_tag="ROH59_002162"
     CDS             complement(16267..16983)
                     /locus_tag="ROH59_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804642.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            complement(16980..17666)
                     /gene="hisQ"
                     /locus_tag="ROH59_002163"
     CDS             complement(16980..17666)
                     /gene="hisQ"
                     /locus_tag="ROH59_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HDX4804643.1"
                     /translation="MLYGFSSVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERR
                     YSVGVKRADL"
     gene            complement(17756..18538)
                     /gene="hisJ"
                     /locus_tag="ROH59_002164"
     CDS             complement(17756..18538)
                     /gene="hisJ"
                     /locus_tag="ROH59_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HDX4804644.1"
                     /translation="MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(18759..19541)
                     /gene="argT"
                     /locus_tag="ROH59_002165"
     CDS             complement(18759..19541)
                     /gene="argT"
                     /locus_tag="ROH59_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HDX4804645.1"
                     /translation="MKKSILALSLLVGLSAAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGPSVKDKKYFGDGTG
                     VGLRKDDAELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(19807..20376)
                     /gene="ubiX"
                     /locus_tag="ROH59_002166"
     CDS             complement(19807..20376)
                     /gene="ubiX"
                     /locus_tag="ROH59_002166"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HDX4804646.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTL
                     SLETDFSLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAVTLPEDLFARWQGA"
     gene            complement(20471..21988)
                     /gene="purF"
                     /locus_tag="ROH59_002167"
     CDS             complement(20471..21988)
                     /gene="purF"
                     /locus_tag="ROH59_002167"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDX4804647.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVVMIIGHGMVAFRDPNGIRPLVLGKRDIDDNRTEYMVASESVALDTLG
                     FEFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIEAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            complement(22025..22513)
                     /gene="cvpA"
                     /locus_tag="ROH59_002168"
     CDS             complement(22025..22513)
                     /gene="cvpA"
                     /locus_tag="ROH59_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HDX4804648.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
     gene            complement(22954..23616)
                     /gene="dedD"
                     /locus_tag="ROH59_002169"
     CDS             complement(22954..23616)
                     /gene="dedD"
                     /locus_tag="ROH59_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HDX4804649.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPATIAANNTEFEPEPA
                     PVVPPKPKPVESPKPKVEAPPAPKPEPKPVVEEKAAPTGKAYVVQLGALKNADKVNEI
                     VGKLRGAGYRVYTSPSTPVQGKITRILVGPDASKEKLKGSLGELKQLSGLSGVVMGYT
                     PN"
     gene            complement(23606..24874)
                     /gene="folC"
                     /locus_tag="ROH59_002170"
     CDS             complement(23606..24874)
                     /gene="folC"
                     /locus_tag="ROH59_002170"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDX4804650.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVGQEKGA
                     LLQRRGVEWNYSVTDHDWTFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            complement(24944..25858)
                     /gene="accD"
                     /locus_tag="ROH59_002171"
     CDS             complement(24944..25858)
                     /gene="accD"
                     /locus_tag="ROH59_002171"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HDX4804651.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            complement(26014..26673)
                     /locus_tag="ROH59_002172"
     CDS             complement(26014..26673)
                     /locus_tag="ROH59_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX4804652.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFS
                     NPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLLFTYAGYFFGTLPFIQSNLKLMIVGIIFVSILPGVFEFIRHKRAAARAA
                     K"
     gene            complement(26756..27568)
                     /gene="truA"
                     /locus_tag="ROH59_002173"
     CDS             complement(26756..27568)
                     /gene="truA"
                     /locus_tag="ROH59_002173"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDX4804653.1"
                     /translation="MSDQQQPPVYKIALGIEYDGSRYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            complement(27568..28581)
                     /locus_tag="ROH59_002174"
     CDS             complement(27568..28581)
                     /locus_tag="ROH59_002174"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDX4804654.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFAQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(28647..29783)
                     /gene="pdxB"
                     /locus_tag="ROH59_002175"
     CDS             complement(28647..29783)
                     /gene="pdxB"
                     /locus_tag="ROH59_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HDX4804655.1"
                     /translation="MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVR
                     SVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSS
                     LLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGITTLLCDPPRADRGDEGDFRS
                     LDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALL
                     TCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSK
                     LIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            29882..30877
                     /gene="flk"
                     /locus_tag="ROH59_002176"
     CDS             29882..30877
                     /gene="flk"
                     /locus_tag="ROH59_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HDX4804656.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGAGNQPLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMALKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDIL
                     NQLYQRRVKGIEPRDMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            complement(30874..32052)
                     /locus_tag="ROH59_002177"
     CDS             complement(30874..32052)
                     /locus_tag="ROH59_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose transporter"
                     /protein_id="HDX4804657.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVSAPFKFALLVVGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(32317..33537)
                     /gene="fabB"
                     /locus_tag="ROH59_002178"
     CDS             complement(32317..33537)
                     /gene="fabB"
                     /locus_tag="ROH59_002178"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HDX4804658.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            33696..35702
                     /gene="mnmC"
                     /locus_tag="ROH59_002179"
     CDS             33696..35702
                     /gene="mnmC"
                     /locus_tag="ROH59_002179"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HDX4804659.1"
                     /translation="MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNHLEARFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAYPQAQLQRLHFISFEK
                     FPLARADLALAHQHWPELAPWAEQLQAQWPLPLPGCHRLLLDEGRITLDLWFGDINEL
                     TSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQEAGFTMQKRKGFGRKREMLCGVMELTLPLPCSTPWFNRTGSSKREAAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFAR
                     RFYDLLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPTELAVAVEANAVEQITGVA
                     TNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIHYQYQLQDLSRKDDGWLLNFAGDQ
                     QATHSLVVLANGHQISRFSQTSSLPVYSVAGQVSHIPTTPELAKLKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEETAYSDEDQQQNRQRLIDCFPQVQWAKEVDVSGKEARCGV
                     RCATRDHLPMVGNVPDYDATLVEYASLAEKKDEAVSAPVYDDLFMFAALGSRGLCSAP
                     LCAEILAAQMSEEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG"
     gene            complement(35823..36101)
                     /locus_tag="ROH59_002180"
     CDS             complement(35823..36101)
                     /locus_tag="ROH59_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HDX4804660.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWEHLFQQASQQ"
     gene            complement(36135..36683)
                     /gene="epmC"
                     /locus_tag="ROH59_002181"
     CDS             complement(36135..36683)
                     /gene="epmC"
                     /locus_tag="ROH59_002181"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HDX4804661.1"
                     /translation="MNSTHHYEQLIEIFNSCFADEFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     ALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLANGIPERPARFIKA
                     LQNYYHTPELTAEQFPWPEALN"
     gene            complement(36683..37492)
                     /locus_tag="ROH59_002182"
     CDS             complement(36683..37492)
                     /locus_tag="ROH59_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDX4804662.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALVAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN"
     gene            complement(37492..38316)
                     /gene="mepA"
                     /locus_tag="ROH59_002183"
     CDS             complement(37492..38316)
                     /gene="mepA"
                     /locus_tag="ROH59_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HDX4804663.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IIGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSRQVSNLGMGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPTLWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI"
     gene            complement(38320..39405)
                     /gene="aroC"
                     /locus_tag="ROH59_002184"
     CDS             complement(38320..39405)
                     /gene="aroC"
                     /locus_tag="ROH59_002184"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDX4804664.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTEIPRW"
     gene            complement(39440..40372)
                     /gene="prmB"
                     /locus_tag="ROH59_002185"
     CDS             complement(39440..40372)
                     /gene="prmB"
                     /locus_tag="ROH59_002185"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDX4804665.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNRAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPEAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLIAAREHFAIYKD"
     gene            40538..41089
                     /gene="smrB"
                     /locus_tag="ROH59_002186"
     CDS             40538..41089
                     /gene="smrB"
                     /locus_tag="ROH59_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HDX4804666.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWLPPELP"
     gene            complement(41149..41973)
                     /locus_tag="ROH59_002187"
     CDS             complement(41149..41973)
                     /locus_tag="ROH59_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001527383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2544 domain-containing protein"
                     /protein_id="HDX4804667.1"
                     /translation="MKKMSGLFFLLLTGLLSATAWADVTFRDVKTYTGFWGNGATTKV
                     VFRIDVLTPEGVYYGEYAQDGYTLWLGNIPNTVWTGPGSAPTMNITHQSNTVDNSNCP
                     GITDGWSCVDLGVDIIVHGETHGCPWLVSTNTVSTAARGYTYIGPSAKQTRCPTEPVG
                     PYDISWNENYVLHNKMLTLQSTGGVITQTLSTYLMRDGRVCDGSRMDDRGAYCRFMSY
                     MITFSTSGCDDSKVTVTPVAHPITDKQLHDMQIRIDTSSQQPIDATCRFQYILNEL"
     gene            complement(41975..42502)
                     /locus_tag="ROH59_002188"
     CDS             complement(41975..42502)
                     /locus_tag="ROH59_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4804668.1"
                     /translation="MSLKRIFHCAAALAAVLLTPNVQAADNLHFYGNLLSKSCTLVVQ
                     GEVLAEVHFPTVSRRDLMVTGQSARVPVVFQLKDCKGPAQYEVRVTLTGTEDSEQPGF
                     LALDAASTAQGVGIGMEKTDGTAVLINNTSGATFVLSSGNNDLHFNAWLQAKSGRDVT
                     MGDFTASLTATFEYI"
     gene            complement(42499..42978)
                     /locus_tag="ROH59_002189"
     CDS             complement(42499..42978)
                     /locus_tag="ROH59_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4804669.1"
                     /translation="MKRFALCLFGCYCGIAQAADSDITFHGTLVSPPACAISDGKTVE
                     VEFRDVIIDNINGNNFRQNVPYTITCDPDVRDDAWEMTLSWTGSQTSYDNAAIETNVT
                     GLGIELQQNGQPFTLGTPLKINLSTPPTLQAVPVKASDASLSEGTFSAWATLQVDYQ"
     gene            complement(42975..43466)
                     /locus_tag="ROH59_002190"
     CDS             complement(42975..43466)
                     /locus_tag="ROH59_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4804670.1"
                     /translation="MKGVLLPVAGMVLLACGSAWADSKTVNLTLRILVDAPPPCTVKG
                     SAVEFGNVIIKNIDGSNYRQPVGYTLNCSNSVSDDLQMQLQGTTTTINGETVLSTGIN
                     GFGIRIQDASSHAPVALAGNNWLPFNVNSRPGFEAVPVKQSGTQLTASEFSATMTMVV
                     EYQ"
     gene            complement(43483..44235)
                     /locus_tag="ROH59_002191"
     CDS             complement(43483..44235)
                     /locus_tag="ROH59_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDX4804671.1"
                     /translation="MFYKLSCSMVVSTTLAVLLTTTNLAAHASVTPDRTRLVFNESDK
                     SISVTLRNNNEKLPYLAQSWLEDEKGNKITSPLAVLPPVQRIDAMMNGQVKIQALPDI
                     HTLPSDRESLFYYNVREIPPKSGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKV
                     TLTRSGQDYIVNNPTPYHVIISDASTQKKGLTAAGFKPLVMPPKTSQPLKAKMNSAPV
                     LTYINDYGARLPLVFRCEGDTCKVDEAQSLKG"
     gene            complement(44255..46903)
                     /locus_tag="ROH59_002192"
     CDS             complement(44255..46903)
                     /locus_tag="ROH59_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX4804672.1"
                     /translation="MPNHSNFRLRGIACYIALAISGGSVNAWADDSIQFDPRFLELKG
                     DTKIDLGKFSKKGYVDAGKYNLRVFINKQSLSDEYDINWYVSENDPTKTYACLTPELV
                     AALGLKEGIAKSLQWTHNDECLKPGQLDGMEVENDLSQSALLLTVPQAYLEYTSSDWD
                     PPSRWDDGISGLIADYSLNAQTRHQEQGGEDSHDISGNGTVGANLGAWRFRADWQSDY
                     QHTRSNDDEDDSSNSTTSKNWDWSRYYAWRALPSLKAKLSLGEDYLNSDIFDGFNYIG
                     SSVSTDDQMLPPNLRGYAPDVSGVAHSSAKVTISQMGRVLYETQVPAGPFRIQDIGDS
                     VSGTLHVRVEEQNGQVQEYDVTTASMPFLTRQGQVRYKVMMGRPEDWNHKTEGGFFSG
                     GEASWGVADGWSLYGGALADEHYQSAAMGVGRDLAQFGALAFDVTHSHVNLDHDSAYG
                     KGKLDGNSFRVSYAKDFDELNSRVTFAGYRFSEKNFMTMSEYLDASQSDMARTGNDKE
                     MYTITYNQNFAAAGVSVYLNYSHRTYWDRPEQTNYNLMFSHYFNMGSIRNMSISVTGY
                     RYEYDDNTDKGMYLSMSIPWSDSSTVTYNGSYGSGSDSSQVGYFNRIDDATHYQINVG
                     TSEQHGSVDGYLSHDGTLAKVDLSANYHEGEYRSAGIALQGGATLTAHGGALHRTQNM
                     GGTRLLIDADGIANVPVESNGAPVYTNMFGKAVVADINNYYRNQAYIDLNNLPEDAEA
                     TQSVVQATLTEGAIGYRKFKVISGQKAMAVLRLRDGSYPPFGAEVKNDEQQQVGIVDD
                     EGNVYLAGINAGEHMMVFWEGSAQCEIVLPKPLPADLFRGLLLPCEQKGTTAPDSLAP
                     EIKPVIQDQTRQVTPSEAPTSISATQ"
     gene            complement(46984..>47513)
                     /locus_tag="ROH59_002193"
     CDS             complement(46984..>47513)
                     /locus_tag="ROH59_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4804673.1"
                     /translation="VMGAVVSSSAFAAGNNGTARFYGTIEDSPCSIVPDDHKLEVDMG
                     DIGAAKLTGGGTTTPKDFQIHLQDCVFTTESNMETTFTGTNYAGPANADNYALFNVDS
                     GVAMNHVSLVIGDTHGKGYKVGEKIVQPIVMDASTSKGKDKQTLNFKAWLVGETDAPD
                     LGQFETLTTFQITYL"
BASE COUNT        11507 a        12945 c        11920 g        11141 t
ORIGIN      
        1 attcagtagt gaattcttaa acgaggcatt ttcacacaat tatcttacag ataaaaaaac
       61 cacacttaca attaagaatc agaacaattc actacataac attacttatt aagcatatgc
      121 acctcattat tttgccatta ttaagttatt aacagcacaa tcgagccttc ccctctggca
      181 aaatcttatt ctgcagacct tcaaaacacc gtcctggggg agtacattgt tctaagctga
      241 cttccacggc agggagtggc gataacagca aaaaaggtca agattcatgt cccccattga
      301 aaaatccagc aaattagaga atgtctgtta tgacatccgt ggtccggtgc tgaaagaagc
      361 aaaacgcctg gaagaagaag gtaacaaggt tctgaaactg aacatcggca accctgcccc
      421 gttcggtttt gacgcgccag atgaaattct cgttgacgtg atacgcaacc tgcctaccgc
      481 tcaagggtat tgcgattcca aaggtcttta ctccgcgcgt aaagccatca tgcagcacta
      541 ccaggctcgt ggcatgcgtg atgttaccgt ggaagatatt tacatcggca atggtgtatc
      601 ggagcttatc gttcaggcaa tgcaagcatt gctgaacagc ggggacgaaa tgttggttcc
      661 tgcacctgat tacccactat ggaccgcggc ggtttcactc tccagcggta aagcggtgca
      721 ttatctttgc gatgaatcct ctgactggtt cccggacctc gatgatattc gcgctaaaat
      781 tacgcctcgt acgcgtggga tcgttattat caacccaaat aacccaaccg gcgcggtata
      841 ttccaaagag cttttaatgg agattgtgga gattgcacgt cagcataatc tcattatctt
      901 tgccgatgaa atttatgaca aaattctcta cgacgacgct gagcatcact ccattgcgcc
      961 gcttgcacct gacctgctga ccattacctt taacggactg tcgaaaacgt accgcgttgc
     1021 aggcttccgt caggggtgga tggtgttgaa cgggccgaaa aaacacgcta aaggttacat
     1081 cgaaggtctg gaaatgctgg cttcaatgcg cctgtgtgct aacgttcctg cgcaacacgc
     1141 cattcagacc gcactgggtg gttatcagag catcagtgaa tttattaccc ctggcggtcg
     1201 tctttatgag cagcgtaacc gcgcgtggga attgatcaac gatattccgg gcgtttcctg
     1261 cgtgaaacct cgtggtgcgc tgtatatgtt cccgaaaatc gacgccaaac gctttaacat
     1321 tcacgacgat cagaaaatgg tgctggattt cctgttgcag gaaaaagtcc tgttggtgca
     1381 agggacggca ttcaactggc cgtggccgga tcacttccgc attgtcacgc taccgcgtgt
     1441 cgatgatatc gagctgtctt tgagtaagtt cgcgcgtttc ctttctggtt atcatcagct
     1501 gtaatcttaa tttcactgcc ggagattgca tccggcagtg ttatcccgcc acaatgacct
     1561 gatgatgtca tcatacgtaa ggtcactatg aaacagagcc atttttttgc ccatctctcc
     1621 cgcctgaaac tcattaaccg ctggccgcta atgcgcaacg tgcggacgga aaatgtgtcc
     1681 gaacacagtt tgcaggtagc gatggtcgcc catgcgctgg cagctatcaa aaatcgtaaa
     1741 tttggcggta atgtcaacgc cgaacgtatc gctttactgg cgatgtacca cgatgcttca
     1801 gaagtgctca ccggagatct ccctactccg gtgaaatact tcaattcgca aatcgctcag
     1861 gaatacaagg ctattgaaaa aatcgctcag caaaaactgg tcgatatggt tccggaagag
     1921 ctacaggata tctttgcgcc gttaattgac gagcatgcat atagcgatga agaaaaatcg
     1981 ctggtgaaac aggcagatgc actgtgtgca tatctgaaat gtctggaaga actcgcggcc
     2041 ggaaataatg aattcttgct ggcaaaaacg cgactggaag cgacgcttga agcgcgtcgc
     2101 agccaggaga tggactactt catggaagta tttgttccca gcttccatct ttcgctcgat
     2161 gagattagcc aggattcacc gctgtaagca gctggagtct gcgtcgcatc aggcaataag
     2221 cgccggatgc gacatcaggc tcttgtcaaa acggaaacag catcgggatc atcaccacac
     2281 aaaccgccat cacgataatg gtgaacggta cccccaactt aacaaagtca ctgaagctgt
     2341 aattccccgg acctaaaacc agtgtgttaa caggtgaaga tatcggtgtc ataaaggcgg
     2401 cggatgctgc catcgccacg accatcgcaa atggataagg cgacaccccc atcgttttgg
     2461 cagcagccag cgcaatcgga gccatcaaca ccgccgtcgc agtattagaa ataaatagcc
     2521 caataaccgc cgacaagaca aacaaacaac ccagcatcat atgtggccca taaccgccgc
     2581 caatgtccat cagccctttc accgccagcg cgacacctcc cgttttctgt aatgccacag
     2641 caaacggcat catcccaacg atcaaaataa tgctcggcca gtgaatggat ttataggcac
     2701 tttcggcatc gatacagcgg aatttcccca tcagcaggca ggcgatgata gcggcaacag
     2761 gattaggaat ttcatcggtc agcattaacg ccaccattag caccagacag aaaatggcat
     2821 ggggtgcctg gctgtgcgcg ggcgatgctt cactcacctc ttccggtaag ttcagcgcca
     2881 cgaagtcgcg gccctgtttg gccagcatac cgatcagttt ccagttacca acaaccagaa
     2941 tgatatcgcc cagcagcaga ggctcatccg ccagcgaacc ttccagcgcc acaccattgc
     3001 gctttagccc caccacattc aatccgtagc gggtacgaaa accaatttcg cgcaccgatt
     3061 taccaataag ttctgactca ggaattaatg aaatctctgc catgcccaca tcaagggcct
     3121 ggtcagaaaa atactcgccg cgcagtacca tcggctccag caattgctca ctacaaaatt
     3181 gccggagatc gacatcagcc gcagacatat caataagcaa aacgtcacgc gcgcgaaatt
     3241 cagaaacccc attaacgttc acgataacgc gacgaaaacg ccgccagcgt tcaacaccga
     3301 tgacgttagc accataacgt tcacgtaatt tgagatcgtc cagtcgttga ccaatcattg
     3361 gcgatccggg gcgaatagcc agacgtcgcg cacgcccggt cagtcgatat tcacggataa
     3421 gatcgcgaaa ggttcggcgc gtccagcctt cgcgttgtgg ggtctgggta tcccctttca
     3481 gcatgaaacg catcactaac atatacaaaa tacccagcac cagcacgacc aggccaatag
     3541 gtgttacgct aaagaaactg aagccgtgat agccttcacg cagtaattca ctgttgacta
     3601 ccaggttcgg cggcgtcgcc accagcgtca tcatgccgct tatcagcccg gcaaaactta
     3661 acggcatcat cagacgcgac ggcgacgttt gcatacgcat ggcaacgctt aacaccacgg
     3721 ggataaagat agcgacaacg ccggttgaac tcataaacgc gccaagtccc gcgacggtca
     3781 gcatcaacaa aaccaacatt ttgatttcac tgttgcccgc cactttgacc agccatgtcc
     3841 ccattacagt ggcaacaccg gtacggacca aaccatcgcc aataatgaac aaggcggcaa
     3901 tcaggacaac gttaggatcg gaaaagccgg aaaatacttc ggggaccgtc agcgttccgc
     3961 ttaatgcaaa cgcgacaata acaaacaaag cgaccgcatc catacgcact ctgcccgtcg
     4021 caaacaagac gatggcaacg gccagtaatg aaagaaccca aatcaattca ccgttcacaa
     4081 cttatccttg ttaattgagg gggataactt gattctgcca taaaaaagcc ccgacgagac
     4141 ggggctaaat catgatcagg tgtttcactg aataataaca tcgccatttg gctgtttggt
     4201 cacagtaatt tgctccagac tgtggaggac taaatcgact tcattcaggc gcggggtatc
     4261 tgccggggca ttaaccgcaa taacatggca acccgccgcc agacctgaaa gcacgccagc
     4321 gggagcatct tccaccacaa cacactcctg cggcgcaagc cccagcagct gcgcgcctaa
     4381 cagatacgca tcaggttctg gttttccgcg cttcacccgc tcagcggtta caaacacctc
     4441 tggcgcggga agccccgcta ttttatgacg cgctcgcgct accggcatgg agccagaagt
     4501 cacaatagcc cacggaatac ctgctttatt caaatgattg agtaaggcga ttgcccccgg
     4561 aagcgcggta ataccttcgg tttccgtggc ctcgatgtgt tccagacgcg taaactcggc
     4621 ggcaatgtct gcctcggatt tgcccgccat aaaatggcgc agagaggtga tcgcctgttt
     4681 accgtgaatg aaagccagca cctcttccgg cgataaccca tgacgtctgg cccagttgct
     4741 ccacgcccgt tctaccgcag gcagggaatc caccagcgtt ccatcaagat caaacagaaa
     4801 acctttgcac cgcacgcggg cctcctcagg cgttaataat ttgattaatt tcgttggcgc
     4861 tcaaatggta ctgacgcggg caggcatgcc acacattaag catgcgctga tatttttccc
     4921 acattggcgt ctgggcgtta aaaccgtgag ttccagcgtc aaaatgggta tagcgccctt
     4981 ccacattaac cataaagcgg acataaccga ggtaacgtgc ttcagtggcg gcgtcaaagc
     5041 cgaggaaggt gacacgacgt tcatcgatgg attgctggtc ctgcaaatta gaccaggaaa
     5101 catgcaacgc atgatacatc tccataatgt cgatgatagt gcggcaggtt tcttctttca
     5161 gctcgccaaa ctcgcgatcc agttcacgca tctgtaatcc ataaccacgc tcaatgattg
     5221 tttgcaggcg acggtaacgt tcagcatttg ccggatcgag catagtcatc atcttgtact
     5281 ggttagacaa aataagacgt tgcgcgttgg tcatttccat tattgactcc tgtatcactc
     5341 tactacggtg aaaaaaaaga aggctgagta tgccttcttt tatatgcgta atcaggggtc
     5401 aattacaaat catcaaggaa agttttatcc agttgtttga aggcacgctt aagcgtgtca
     5461 gctaatgcct ggtaatcagg cttgccttca acgggtgcca acacctgtcc agactcctgc
     5521 aatttaccgc gaacttcata aaaccagttg aggattgcag gaggtaatgg cgttacagaa
     5581 cgcttgccca gccaccacaa tccctgcatg ggtaaactta aggcgaacag cgcagtggca
     5641 actgccggcc caagctgacc gcccagggca atctgccagc agagagtaaa tacggcgatc
     5701 ggcggcataa aacggatcgc ataacgcgtc atcttgataa cgcgattttc gacaaagact
     5761 ggggcaaggc gtttttccag cggccacgtc tttgagtaat gctgtccccg gcgaaacaag
     5821 ctaaaaaaat taacagaacg attatccggc gttgacatgc ttcacctcaa cttcacatat
     5881 aaagattcaa aaatttgtgc aaattcacaa ctcagcggga caacgttcaa aacattttgt
     5941 cttccatacc cactatcagg tatcctttag cagcctgaag gcctaagtag tacatattca
     6001 ttgagtcgtc aaattcatat acattatgcc attggctgaa aattacgcaa aatggcatag
     6061 actcaagata tttcttccat catgcaaaaa aaatttgcag tgcatgatgt taatcataaa
     6121 tgtcggtgtc atcatgcgct acgctctatg gctccctgac gtttttttag ccacgtatca
     6181 attataggta cttccatgtc gagtaagtta gtactggttc tgaactgcgg tagttcttca
     6241 ctgaaatttg ccatcatcga tgcagtaaat ggtgaagagt acctttctgg tttagccgaa
     6301 tgtttccacc tgcccgaagc acgtatcaaa tggaaaatgg acggcaataa acaggaagcg
     6361 gctttaggtg caggcgccgc tcacagcgaa gcgctcaact ttatcgttaa tactattctg
     6421 gcacaaaaac cagaactgtc tgcgcagctg actgctatcg gtcaccgtat cgtacacggc
     6481 ggcgaaaagt ataccagctc cgtagtgatt gatgagtctg ttattcaggg tatcaaagat
     6541 gcagcttctt ttgcaccgct gcacaacccg gctcacctga tcggtatcga agaagctctg
     6601 aaatctttcc cacagctgaa agacaaaaac gttgctgtat ttgacaccgc attccaccag
     6661 actatgccgg aagagtctta tctctacgcc ctgccgtaca acctgtacaa agagcacggc
     6721 atccgtcgtt acggcgcgca cggcaccagc cacttctatg taacccagga agcggcaaaa
     6781 atgctgaaca aaccggtaga agaactgaac atcatcacct gccacctggg caacggtggt
     6841 tccgtttctg ctatccgcaa cggtaaatgc gttgacacct ctatgggcct gaccccgctg
     6901 gaaggtctgg tcatgggtac ccgttctggt gatatcgatc cggcgatcat cttccacctg
     6961 cacgacaccc tgggcatgag cgttgacgca atcaacaaac tgctgaccaa agagtctggc
     7021 ctgctgggtc tgaccgaagt gaccagcgac tgccgctatg ttgaagacaa ctacgcgacg
     7081 aaagaagacg cgaagcgcgc aatggacgtt tactgccacc gcctggccaa atacatcggt
     7141 gcctacactg cgctgatgga tggtcgtctg gacgctgttg tattcaccgg tggtatcggt
     7201 gaaaatgccg cgatggttcg tgaactgtct ctgggcaaac tgggcgtgct gggctttgaa
     7261 gttgatcatg aacgcaacct ggctgcacgt ttcggcaaat ctggtttcat caacaaagaa
     7321 ggtacccgtc ctgcggtggt tatcccaacc aacgaagaac tggttatcgc gcaagacgcg
     7381 agccgcctga ctgcctgatt tcacaccgcc agctcagctg gcggtgctgt tttgtaaccc
     7441 gccaaatcgg cggtaacgaa agaggataaa ccgtgtcccg tattattatg ctgatcccta
     7501 ccggaaccag cgtcggtctg accagcgtca gccttggcgt gatccgtgca atggaacgca
     7561 aaggcgttcg tctgagcgtt ttcaaaccta tcgctcagcc gcgtaccggt ggcgatgcgc
     7621 ccgatcagac tacgactatc gtgcgtgcga actcttccac cacgacggcc gctgaaccgc
     7681 tgaaaatgag ctacgttgaa ggtctgcttt ccagcaatca gaaagatgtg ctgatggaag
     7741 agatcatcgc gaactaccac gctaacacca aagacgctga agtcgttctg gtggaaggtc
     7801 tggtcccgac acgtaagcac cagtttgccc agtctctgaa ctacgaaatc gccaaaacgc
     7861 tgaacgcaga aatcgtcttc gttatgtctc agggcactga tactccggaa cagttgaaag
     7921 agcgtatcga actgactcgc aacagcttcg gcggtgcaaa aaacaccaat attaccggcg
     7981 ttatcgttaa caaactgaac gctccggttg atgagcaggg tcgtacccgt ccggatctgt
     8041 ccgagatttt tgacgactcc accaaagcaa aagtgaacaa cgttgatccg gcgaagctgc
     8101 aagaatccag cccgctgccg gttctcggcg ctgtgccgtg gagctttgac ctgatcgcga
     8161 ctcgtgcgat cgatatggct cgccacctga atgcgaccat catcaacgaa ggcgacatca
     8221 atactcgccg cgttaaatcc gtcactttct gcgcacgcag cattccgcac atgctggagc
     8281 acttccgtgc cggttctctg ctggtgactt ccgcagaccg ccctgacgtg ctggttgccg
     8341 cttgcctggc tgccatgaac ggcgtagaaa tcggtgccct gctgctgact ggcggctacg
     8401 aaatggacgc gcgcatttct aaactgtgcg aacgtgcttt cgctaccggc ctgccggtat
     8461 ttatggtgaa caccaacacc tggcagactt ctctgagcct gcagagcttc aacctggaag
     8521 ttccggttga cgatcacgag cgtatcgaga aagttcagga atacgttgct aactacatca
     8581 acgctgactg gatcgattct ctgactgcca cttctgagcg cagccgtcgt ctgtctccgc
     8641 cagcgttccg ttatcagctg actgaacttg cgcgcaaagc gggcaaacgt atcgttctgc
     8701 cggaaggtga cgaaccgcgt accgttaaag cagccgctat ctgtgctgaa cgtggtatcg
     8761 caacttgcgt actgctgggt aatccggcag agatcaaccg tgttgcagcc tctcagggtg
     8821 tagaactggg tgcaggcatt gaaatcgttg atccagaagt ggttcgcgaa aactatgttg
     8881 gtcgtctggt cgaactgcgt aagaacaaag gcatgaccga aaccgttgcc cgcgaacagc
     8941 tggaagacaa cgtggttctc ggtacgctga tgctggaaca agatgaagtt gatggtctgg
     9001 tttccggtgc tgttcacacc accgcaaaca ccatccgtcc gccgctgcag ctgatcaaaa
     9061 ctgcaccggg cagctccctg gtatcttccg tgttcttcat gctgttgccg gaacaggttt
     9121 acgtttacgg tgactgtgcg atcaacccgg atccgaccgc agaacagctg gcagaaatcg
     9181 cgattcagtc cgctgattcc gctgcggcct tcggtatcga accgcgcgtt gctatgctct
     9241 cctactccac cggtacttct ggtgctggta gcgacgtaga aaaagttcgc gaagcaactc
     9301 gtctggcgca ggaaaaacgt cctgatctga tgatcgacgg tccgctgcag tacgacgctg
     9361 cggtaatggc tgacgttgcg aaatccaaag caccgaactc tccggttgca ggtcgcgcta
     9421 ccgtgttcat cttcccggat ctgaacaccg gtaacaccac ctacaaagcg gtacagcgtt
     9481 ctgctgacct gatctctatc ggaccgatgc tgcagggcat gcgcaagccg gttaacgacc
     9541 tgtcccgtgg cgcactggtt gatgatatcg tctacaccat cgcgctgact gcaattcagt
     9601 ctgcacagca gcagtaatct cgtcatcatc cgcagctttg cgctgcggat atctgaaccg
     9661 gaaatagtca ctatttccgg ttttttattc tcttaatttg cattaatcct ttctgattat
     9721 cttgcttaac tgcgctgcat caatgaattg cgccatctca ctttgcatac ttaccacttt
     9781 gttttgtgca agggaatatt tgcgctatgt ccgcaatcac tgaatctaaa ccaacaagaa
     9841 gatgggcaat gcccgatacg ttggtgatta tcttttttgt tgccatttta accagccttg
     9901 ccacctgggt agttccggtg ggcatgtttg acagtcagga agtgcagtat caggttgatg
     9961 gtcaaacaaa aacacgcaaa gtcgtagatc cacactcatt tcgcattctg actaacgaag
    10021 caggcgaacc tgagtatcac cgcgtacagc tgttcacgac gggcgatgaa cgcccgggtc
    10081 tgatgaactt cccgtttgaa gggttaacct caggatcgaa atacgggaca gccgttggca
    10141 tcatcatgtt tatgctggtg attggcggcg cgtttggcat tgtgatgcgt acaggaacca
    10201 ttgataacgg tatcctggcg cttattcgcc atacccgcgg aaatgaaatt ctctttattc
    10261 ctgcgctgtt tattctgttt tcacttggcg gcgcaatatt tggtatggga gaagaggccg
    10321 tcgcctttgc cattatcatc gcaccgctaa tggtccggct gggctatgac agtattacca
    10381 ccgtccttgt gacctatatt gccacgcaaa tcggttttgc cagttcgtgg atgaacccgt
    10441 tttgtgtggt tgttgctcag ggtattgccg gcgttccggt gctttctggc tccgggttgc
    10501 gcatcgtggt gtgggttatc gccactctga ttggcctgat ctttaccatg gtgtacgcct
    10561 cacgagtgaa aaagaatcct cttctgtcac gcgtgcatga gtccgaccgc ttctttcgtg
    10621 aaaagcaggc tgatgttgaa caacgtccgt ttacctttgg tgactggctg gtattgattg
    10681 tcctgaccgc cgtaatggtc tgggttattt ggggcgtgat cgttaatgcc tggtttattc
    10741 ctgaaattgc cagccagttc ttcaccatgg gtctggtgat tggcatcatc ggcgttgttt
    10801 tccgccttaa cggcatgacg gttaatacca tggcttcatc ctttaccgaa ggggcgcgaa
    10861 tgatgatcgc ccctgccctg ctggtgggtt tcgccaaagg gattttgctg ctggtcggta
    10921 atggtgaagc gggtgatgcc agcgtgttaa ataccatcct caacagcatt gccaatgcca
    10981 ttagcggtct ggataacgca gtcgcggcct ggtttatgtt gctcttccag gcggtattta
    11041 atttcttcgt gacgtccggt tctggtcagg cggcgttaac catgccgtta ctggcaccgc
    11101 ttggcgatct ggtcggtgtt aaccgtcagg ttaccgtgct ggcgttccag tttggtgatg
    11161 gcttcagcca catcatttac ccaacctcag cttcgttaat ggcgacgctc ggtgtttgcc
    11221 gggtggactt ccgtaactgg ctgaaggtgg gtgcgaccct gcttggactg ctgtttatta
    11281 tgtccagcgt cgtggtgatc ggcgctcagt tgatgggcta ccactaaaaa tgttaagagc
    11341 cgcgattgcg gctctttttt cattctgccg tttcagtctc gacggcttca tttttggcat
    11401 tgcgcttcat ccacaacgcc agcgctttca gcgagtctgg agtgaactca tcgcagcgtg
    11461 cggtgatttc ttccggcgtc agccagcaaa cttcactgac ttcatcttcc tgtagagcga
    11521 agggaccgtg agagacgcag ctgaacaacg cgccccagac acggcaattt ttatcttcga
    11581 aatagaactg cccgtgctcg gcaaagggga caccggcaat gcccaactct tcttccgctt
    11641 cgcgacgcgc ggattccagc agctgctcat cggcctggac tacaccgcct gcggtcgcat
    11701 ctaacatgcc gggtaaaaag tcttttgtct cggtacgacg ctggaccaga attttgccca
    11761 tgccatcatg cacgacgata taagttgcac gatgacgcag acactgtgcc cgcatttgtt
    11821 cccggctggc ttgtgcaatg acttcgttct cttcattgac aatatccacc cattcagtac
    11881 ttgccaaacg acgctgttcc attatcagga aaccttcttt ttctggcgct cttacggcgc
    11941 attttgagtt gtgggtaaat tacggattaa tcgcgacctg cgcaatgata ctttgatcat
    12001 tgagtgcgat tacactaagt acgtcattat ccagcatgcc ataactcgcc ggattaccgc
    12061 ctttcggaat actcaccgag ccggggttga agtggaaaat ctccccccgc tgttctgcca
    12121 ctggcagatg ggtatgaccg tacaccagca catcgttctg gtttaaagca ggtagatttt
    12181 ccgggccaaa aagatgacca tgcgtcaaaa acagacgttg tttttccagt aatacctgtt
    12241 gccacggcgc ggttatcggg aaatgcagca gcatttgatc cacttcgctg tcgcagttgc
    12301 cgcgcacagc gataacctta tgtgccactt cattaagccg ttcagcgact ttggctggcg
    12361 cgtaaccctc cggtaaagca ttacgcgggc catgattcaa cacgtcgcca aggatcacca
    12421 gccactgggc accgctttgg gcaaacaact ccagaacacg ttccgtcgcc ggtaacgacc
    12481 catgaatgtc cgatgcaaac atcagtttca tcactcactc ctcgtcgaaa aaacgtaagc
    12541 tatgatactg gattctgtcg ttgctatcag ccagattgct tcgccgaaag tgcaataaaa
    12601 cgctggacag acgctcgctg ccactggaat gtcgcataat ccaccaggcg ttccggcacc
    12661 tcatcgccat gtagtaccag gcggttaatc attagcgcca gatcagtatc agcaatgcac
    12721 cattcaccaa ataaattcgg ctgacccagt gctaacaaat gctctgccat cgcgaacagt
    12781 ttctctgcac tggcttttcc ctcggccgtt agtggcgctt ttttcgcccc cgcaaagaca
    12841 acatccgtcg ggcgttcttc gcggatgggc atcagatcgc tgcgcagcca ggcctgaatc
    12901 tgtcgtgcac gcgcacgatt ttctaaatca agcggataaa tacgttccca ggtcggtggc
    12961 gcaaatcgat cttccagata ctccgcaatg gcagaagatt cactcaactc aaaatcatcg
    13021 atttgtaata acggcacacg gcgtgtctga ccgtaacctt gccacgtcgg ctgcaaatgt
    13081 tcaccgctgt cgaggtcgat ggtcttgata tgaaacgaca ggcctttctc ctgcaacgcc
    13141 acccaggcgg ataacacata aggggagaaa aaatgggcat ctgaccaaag cgtaatagcg
    13201 ggtttactca ttatgtcctc ggcaataaag ggggcttgct atcaaactat agagcctttt
    13261 tgtcactgtc acgtgacgaa tactcacgca agtcgccgcg ctttctatac ttgtggtgtt
    13321 cagatgatta gacaaccgga gctgcaatga tcgatctcta tttcgccccg acacccaatg
    13381 gtcacaaaat tacgctgttt ctcgaagaag cagggctgga ttatcgcttg ataaaggtag
    13441 acctggggaa aggaggtcag tttcgcccgg aatttttgcg catttcgcct aacaacaaaa
    13501 ttccggcaat tgttgatcat tctccagccg atggcggcga accgctaagc ctctttgagt
    13561 ctggtgccat tttgttgtat ctggctgaga aaacgggact ctttttgaat catgaaacgc
    13621 gtgaacgcgc cgtcacatta cagtggttat tctggcaggt aggcggactg gggccgatgc
    13681 ttgggcaaaa tcatcatttt aatcacgcag ccccccaaac cattccttac gctattgaac
    13741 gttatcaggt tgaaactcag cgtctgtacc atgtactgaa caagcggctg gaaaattcgc
    13801 cctggctggg aggcgagaac tacagcattg cggatattgc ctgctggccg tgggttaatg
    13861 cctggactcg ccagcgaatt gacctcgcaa tgtatccggc agtcaagaac tggcatgagc
    13921 ggatccgttc gcgccctgcc accgggcagg cactgctaaa agcacaacac ggtgatgagc
    13981 gttcggatag ttaacagaaa caggttctcg tgtattattt cattctaagt aaaacaacgg
    14041 agaacctgca atggcacaac ctgccgctat tattcgtata aagaaccttc gtttacgtac
    14101 gtttatcgga attaaggaag aagaaattaa caaccgtcag gatattgtta tcaatgtgac
    14161 gatccactac cccgccgata aagcgcgcac tagcgaagat atcaacgatg cgctgaatta
    14221 tcgcaccgta acgaaaaaca ttattcagca tgtagagaat aaccgtttct ctttgctgga
    14281 aaaattaact caggatgtgc tcgatatcgc acgcgaacat cactgggtga cgtatgctga
    14341 agtggagatc gataaactgc acgcgctgcg ctacaccgat tcggtatcca tgaccttaag
    14401 ctggcagcgt taaccaccat atcgggaggc tgcatgaaca tagtgatcac cggagggacg
    14461 ggattaattg gtcgccattt gattccacgt ttgctggacc tgggccatca aatcacggta
    14521 gtgacgcgta acccgcagaa agccagttcc gttctcggcc cccgagtgac actatggcaa
    14581 gggcttgccg aacaaagcaa cctcaacggc gttgatgcgg taatcaacct ggccggagaa
    14641 ccgattgctg ataaacgctg gactcacgag cgaaaagagc gtctctgcca aagccgctgg
    14701 aataccacgc aaaaactggt cgatttgatt aatgccagcg acacgccacc gtcggtactc
    14761 atttccggct cggcaacggg ctattatggc gacttaggtg aagtggtggt taccgaagag
    14821 gaaccgccgc ataacgaatt tacccataaa ctctgcgccc gctgggaaga gattgcctgt
    14881 cgggcgcaaa gtgacaaaac gcgagtgtgc ctgctgcgta ccggcgtagt gctggcacca
    14941 gacggtggta tcctcggtaa aatgctgccg ccatttcgtt ttggcctggg cgggccgatt
    15001 ggctccggtc ggcagtatct ggcctggatt catattgatg atatggtcaa cggcattctc
    15061 tggctgctgg ataacgagct gcgcgggcca tttaatatgg tttcgcccta cccggtacgc
    15121 aatgaacaat ttgcccatgc gctcggtcat gcgctgcatc gcccgaccat tttgcgcgtc
    15181 cccgcgaccg ccattcgact gttaatgggc gaatcttcag tactggtatt aggtggacaa
    15241 cgcgcgctgc caaaaaagct ggaagaagcg ggttttgcgt ttcgctggta cgatttagaa
    15301 gaggcgctgg cggatgtcgt tcgctgatgt ggtttactgc aaacatccgc cagcggaaac
    15361 gctgatgaat aaatatagat aattcagaac tatttttagc ggactgcaac ttttacattt
    15421 cagcggaagc ggactcgcaa attccccatg aaatactccg gcagcgttaa ccaccggaga
    15481 ggaaattatt tcagcgaacc tttaaggaac tgttgcagac gagggctttg cgggttaccg
    15541 aataactgct ccggcgcccc ttcttcttct attttcccct gatggaggaa aatgacgtga
    15601 gtagaaacat gacgagcaaa gcccatttcg tgagtcacta ccaccatggt tttcccctct
    15661 tctgccagtt gctgcataat acgcaacact tcgcctacca gttcaggatc gagcgctgaa
    15721 gtaggttcat caaacagtaa aacttccggt tccatcgcta gcgcccgcgc gatagaaaca
    15781 cgctgttgct gaccaccgga caggtgcacc gggtatttcc cctgcgcacg ttcgtctatc
    15841 ccgacttttg ccagatactt caccgcccgc tcgcgcgctt cctgcttgct caggcccaac
    15901 acctgaatcg gcgcttccat gacgttttcc agcaccgtca tatggctcca gagattgaag
    15961 tgctgaaata ccatcgtcag gcgtgtgcgc aataagcgca gctgattttt atcggcgact
    16021 ttgagttgac catctttatc gcgcaccaga ttgatcgtct ggccattgac cacgatcgat
    16081 ccatcgctcg gtttttcgag gaagttaatg cagcgcagaa aggtactttt ccccgatccc
    16141 gacgatccga tgatgcttat gacatctccg gcattcgctt gcaatgagac ccctttcagc
    16201 acttcgtgtt cgccgtagcg tttgtgcaaa tcgataacgt ttaatttatt ctcggacatc
    16261 gtattctcag tgcgttgaag aaggtttcac atgctgcaac cagcgttttt cagctctacg
    16321 aaagaggctg atcagaacat aagagatgat taaatagagc accgcggcaa tgccgaaagc
    16381 ggtaaaaggt tgatatgtgg cggcgttaat atcgcgggca attttcagca gatccggcac
    16441 cgtggcagta aatgccagcg cagtagagtg cagcatcagg atcacttcgt tgctgtatgc
    16501 cggtaacgca atacgcagcg cagaaggcaa aataatgcag cgatacattt taaaggtcga
    16561 gaagccatag gctctggcgg cttcaatttc cccatgcggc actgaacgga ttgccccggc
    16621 aaaaatctcg gtagtgtaag cgcaggtgtt aagcgtcagc gccagcacgg tacagttcag
    16681 gccactgcga aaaaaggcgt taaggaactc ggttccctta acaatctcca gcgtgtacat
    16741 gccggaatag aacaccagca actgaacata cagcggcgta ccgcgaaaaa tataggtaaa
    16801 taaccagatt ggaaactgga tgtatttatt acttgagacg cgaccaatcg ccagaaacag
    16861 cgccagaact ccgcctatca ctaccgacaa aatcagcagc cacagggtga tcgccacgcc
    16921 agtaaagcga taaccgtcag tccacagcag tggtttccag tattcatgta agatttcgat
    16981 cacaggtcag ccctcttcac acccacggag tagcggcgct caaggaacag cagcacacca
    17041 ttggaaacgg tggtgaaaac aagataaatc acgccgcaga cgatagcgaa atagaacggt
    17101 tcccaggtac ttttgcctgc cagctgcgtg gctttgacca catcttccag gccgagtaac
    17161 gaaaccagtg cggtagattt gaggatcacc tgccagttgt tgccaatgcc tggcagggcg
    17221 taacgcatca tcgccggaaa catgatccgc cgaaacactt gcccacgagt aaaaccgaac
    17281 gccgtcgccg cctctatatg tcctttcggc actgccataa acgcgccacg aaacgtttcg
    17341 gtaaaataag caccgtagat aaaaccgaga gtgataatac ctgcgaccat cggatcaata
    17401 tcaatctgcc cgacgcccat cgcctccgtc accgtgttta gcgcaatctg caaaccgtag
    17461 aaaatcagca gcatcaatac taaatccggc acgcctcgaa tcagcgtggt gtacccttcg
    17521 aaaataaggc ccgaaagccg attttgtgag agcttaccgc cagcgccaat taaaccgatg
    17581 attacagcga gcactacaga gctgatagcc agctccagcg tgacgagcgc accctgtaaa
    17641 ataacacttg aaaacccata caacatgctg cctgtcctgt cgtgtgtggt gaattaccgc
    17701 ctcttgtctc cctccggtta cccgaaggga gcgggctttc tttcaccgat ggcgattaac
    17761 caccataaac atcaaaatcg aagtactttt tcgctaattt ctcgtaagta ccgtcagcgc
    17821 gcatttcggc aaaggctttg ttcagtgcct cgcgcagttc gttatcttct ttacgcaggc
    17881 ccatgccggt ccctacgcca aacagttttt catctttaac agacgggcca ccgaatttgt
    17941 aatctttacc gacgggttgt ttgaggaaac cttcgctggc tgcgacctca tcctggaacg
    18001 cggcatcaat acgtccggca gtcaggtcag aataaatgtt gtcctgcccc tgataagaaa
    18061 cgatttcaat gccttttggt gcccagtgtt cgttaccgaa cgtctcctgg gtggtgccct
    18121 gcaatacgcc tacccgtttg cctttcagcg attcgactgt cggctgaatg tcggaatttt
    18181 tcgccaccac cagacgagaa tcggctgcgt acagtttgtc ggtgaaggct atttcttgct
    18241 gacgtttttc cgtaatggaa agcgatgaca tgatggcgtc aatcttcttc gcttttaagg
    18301 acgggattaa cgcatccagt gggttttcga caaacgtaca ttgcgtattg atgcgtttgc
    18361 acaactcctt ggccagatcg atatcgaagc caaccagttc accttgtgaa ttttttgatt
    18421 caaatggcgc ataggtcgga tcggtaccga tgcggatgtt ttgcggaatc gcagcaaatg
    18481 ctgcagttgc gctggagaag gccagaacca gagagagcga tagcaccagt tttttcataa
    18541 tgtcctcaac tgacagtctt tttatcggga atatttacag gtttgttaca cttatcgtgc
    18601 cataaaattg accatcaagg caaaatatcc cgccccgcta gacgtattat ttttcattaa
    18661 aaatgcttaa gtatgcattt caatgcacca cgatagtgca acaaacctgg cgtgcaccat
    18721 gatgatcatt ccatcaggta cagcttccct gcgacgtatc agtcaccgta gacattaaag
    18781 tcaaaatact ttttcgccat cttgtcgtag gtgccgtcct gacgcagctc gccaagcgcc
    18841 ttattaaacg cagccgtcag ttccgcatca tctttacgta gccctacacc ggtgccgtca
    18901 ccgaagtatt ttttgtcttt cactgatggg cctgcaaagg cgaaatcttt accggcgggt
    18961 tgcttaagga aaccttcgct ggcagcaact tcatcttgta acgcagcatc cagacgtcct
    19021 gcagccagat cggaatagac taaatcctgg ttggcatagg ccaccacatc cacgcctttg
    19081 ctacgccagg tctcgttagc gtaagcttcc tgggttgatc cctgcagcac accaacatgt
    19141 ttacctttca gtgaatccag cgttggctga atcggtgaac ctttggcggc aatcaaacga
    19201 gaatctgcgg cgtacagctt gtcggagaaa gcaatctcct gctgacgttt atcggtaatg
    19261 gagagcgacg aaataatggc gtcgattttt ttcgctttca gtgaggggat cagcgcgtca
    19321 aagtcgctgg caacccaggt acatttcacc tgcatccgtt tgcacatctc gttaccgaga
    19381 tcgatatcaa agccaacaaa gtcacctttg gcatctttcg atgagaacgg tgcgtaggtg
    19441 gtatcggttc cgatacgtac cgtctccggt agcgccgcat agctggaagc cgctgcggag
    19501 agaccgacta acaaagacag agcgagaatc gacttcttca tacataaccc tcaagtgaaa
    19561 atggcttttt tatgttgtgt attgtgttgt gtgtttgcag gctctttcat gcaggtctta
    19621 tgccatcttg acgacagcag taacattcaa cgttaaatat gttaataaga agttgcatta
    19681 ttgtcctaaa gttgaagata gcaggtatag cggttgaatc gcagcgtttc gattgaatgg
    19741 cagaaacaaa atgtcgagga tttgatcgcg gttgcaaaat tgccctgaaa cagggcaaca
    19801 gcggagttat gcgccctgcc agcgggcaaa gagatcttca ggaagggtta ccgcaaactg
    19861 gtcaagaaca cgattaaccg tctgatttat cacatcatca agggattgtg ggcgatgata
    19921 aaacgccgga acgggaggca taatcaccgc accgatttct gccgcctgag tcattaaacg
    19981 cagatggcct aagtgcagtg gcgtttcacg cacgcagagc accaacgggc gacgctcttt
    20041 cagcaccaca tctgccgcac gggtcagtaa gccatcagta tagctatgga caatgccgga
    20101 cagggttttg attgaacagg gtaaaatcac catccccaac gtctggaaag aaccggaaga
    20161 aatgctggca gcaatatcgc gcgcatcgtg tgtcacatca gctaacgcct gcacttcgcg
    20221 cagggaaaaa tccgtttcga gggataaggt ctggcgcgcc gcctggctca ttaccagatg
    20281 cgtttcgata tctgtgacat cgcgcagaac ctgtaataaa cgcacgccat aaatcgcgcc
    20341 gctggcaccg ctgatgccta caatgagtcg tttcataaat agttgccctg tcagacttgc
    20401 aggcagactt tgcaggattt cggcgggagt tgcaagtcag ggtgccagac cggcaccctg
    20461 agcgaaggca tcatccttcg ttatgcattt cgagattttc cacttcgttc tgacgttgca
    20521 ctgctttggc gtcgtcatta cgtaaagtat cgaggaaatc gaggtagccc tgatcaacgt
    20581 ctttggtgac gtagacgccg ttgaacaccg agcattcaaa ctgctggata tccgggtttt
    20641 cagcgcgaac ggcttcgatc agatcgttca gatcctggaa aatcaacccg tcagcaccga
    20701 tgatctggcg aatttcatct acttcgcgac cgtgagcgat cagttccgtg gcgctcggca
    20761 tatcgatacc gtaaacgttc gggaagcgaa tttccggtgc cgcagaagcg aggtacactt
    20821 tcttcgctcc ggcttcgcgt gccatctcga taatctgctc agaagtggtg ccacggacga
    20881 tagagtcgtc gaccagcagg acgtttttat cgcggaactc ggcgcggttg gcgttcagtt
    20941 tacggcgcac ggacttacga cgcagctgct gacccggcat gatgaaggtg cggccaacat
    21001 agcggttttt aacgaagccc tggcggtacg gtttgcccag aatacgcgca atttccagcg
    21061 cgatatcgca ggaagtttcc gggatcggga tcaccacgtc gatatccaga tcttcccatt
    21121 cgcgggcaat tttctcgccc agcttcgtgc ccatattcac acgcgcgctg taaacggaaa
    21181 ttttgtcgat gaacgagtcc gggcgagcaa agtatacata ctcaaacagg cacggattgc
    21241 tgaccggatt gtcagcacac tgacgggtaa acaactgccc ttcttcagtg atgtaaatcg
    21301 cttcgccagg ggcgacatca cgcaggaact caaagcccag cgtatcgagc gcaacgcttt
    21361 cggaagcgac catatattct gtgcgattat cgtcaatatc acgtttgccc agtacaagcg
    21421 gacgaatccc gttaggatcg cggaaagcaa ccataccgtg gccgataatc atcaccacac
    21481 aggcatacgc gccgcggatt aagcggtttg tagcagcgat ggcggcgaaa atgttgtcgg
    21541 cttccagcgg gtagtggcgg aagttgtcca gctcgctggc gaagatatta agcagaattt
    21601 ccgagtcgga agtggtgttg atgtggcggc gtttttcttc aaacagtttt ttacgcaact
    21661 cgtgagcgtt ggtcagattg ccgttgtggg caagcgtaat gccatacgga gagttaacgt
    21721 aaaacggctg cgcttcagag gcgctggagc tgccagccgt agggtaacgc acatgaccaa
    21781 tgcccatatt gccctgcaaa cgctgcatat ggcgagcttc aaatacatcg ctcaccagcc
    21841 cgttcgcttt ccgcaaacgg aagcagttat tggcatctat ggtgatgatg ccggcggcat
    21901 cctgaccgcg atgctgaagc accgttaagg catcataaat cgactggtta accggcataa
    21961 caccggcgat accgacaata ccgcacatac gtctttttcc tcgttaagcc acatctcaga
    22021 gcacttacgc tctgggcaag aaacttgacg agctttgcag ataatcaaaa aaccatctga
    22081 tgataaaact gaactgcggg atcagctgtg atttgctcca gtcttcgctt ttcgacaccc
    22141 cggtaaagga gtcgagaaag aagagaatgg cagcaacaat caacacaccg cgcaaggcac
    22201 cgaaacagac gcccaacacc cgatcggtgc ctgacaaccc cgttttctcc accaactggc
    22261 ctatcacgaa gttcacgata gcaccaacga tcagggtagc gataaacagt accgcgatgg
    22321 caatcccatt tcgaaccagt tcgtcttcaa agcccgtaaa ccagactgac aggtaagtgt
    22381 agtaatgact ggcaacaaag aaagcacaac cccatgtcac cagcgataac gcttcacgaa
    22441 caaagccgcg gatcaggcta accagagagg aaaaagcaat caccgcgatt atggcgtaat
    22501 caatccagac catatgtgtc ccacgatttt acgccctgtc atcctgttcg gggcgcattc
    22561 taacagaaaa agaaaacgtt tgcgtaggga tttccttccc gcgcatcaat aaaaatggcg
    22621 ctgaaaaaat attcaacgcc atcgactttt tatgcctttg cggcatcggg caatgcgtgt
    22681 cggatgcggc gtgaacgcct tatccgacct acggctctac ccctgcacag gcctgataag
    22741 acgcactggc gtcacatcag gcaacggctg tcggatgcag cgtgaacgcc ttatccgacc
    22801 tacggttcta cccctgcaca ggcctgataa gacgcgctgg cgtcgcatca ggcaacggct
    22861 gtcggatgcg gcgtgaacgc cttatccgac ctacggttct acccctgcac aggcctgata
    22921 agatgcgcca gcgtcgcatc aggcaaaacc gtattaattc ggtgtatagc ccattaccac
    22981 accacttaag ccagaaagct gcttgagctc acccagcgat cctttcagct tctctttgga
    23041 agcatctggc ccaaccagaa tacgggtaat tttaccctgc actggcgtgg atggcgacgt
    23101 ataaacccga taaccggcac cgcgcagctt accgacaatc tcattcactt tatcggcatt
    23161 tttcagcgcg cccagttgca caacataggc tttacccgtt ggcgctgctt tttcttccac
    23221 gaccggcttc ggttctggct tcggcgcagg tggtgcttca accttcggtt taggcgactc
    23281 caccggtttc ggcttcggtg ggacgaccgg tgcaggttcc ggttcaaact cggtgttatt
    23341 ggctgcaata gtggccggat cgagcgacgg tgctgcggca tcgcctgccc gcacctcttc
    23401 cgctgcgcct tccggcggct gcgtcggcaa cgcctgggtg gcggctggca tcatatcagg
    23461 ctcatcgcga tcgcccgctt tcggcaccag cgggatagcc gcgaactcat cctgataatg
    23521 ttttttctgc ccgtccagca gccctggaag tacaatcacc cccagcgcca ccagcacgat
    23581 cgtgcccact aaccgattct gaaacttact tgccaccgct tctcctcgcg tcaatcactt
    23641 ccatgacatg tgcgaccgtg tggaacgaac cacacaccag cacggtgtct tccgctttag
    23701 cgtccgccat tgcggcatcc catgcctgcg caacgctatc aaatgatttg ccgttaccca
    23761 aatgctcaag cagttgttct gccgtggcac cgcgcggccc ttccagtggc gcacaatacc
    23821 agtcatcaac cacgcttttc aaccaggcca gagttccggc aatatcttta tcatgtagca
    23881 taccgataac cgccagcacg cgcccgtttt tcggtagcgc tttcatacgc ccggtgagat
    23941 attccgccgc atgtggatta tgcgcgacat caaaaataac gcgtggcgac tcgctcacaa
    24001 tctggaaacg tcccggcaaa attgcgctgg caatcccgtc gcgaatggca ttttcactga
    24061 cctccagccc gctggcacgc agtgccgcca gcgccgttgc ggcattcggt tgcgggacaa
    24121 gcggcaacgg cagattttcc agcgtgccgt gagcatcgct aaacgtccag tcatgatcgg
    24181 tgacggaata gttccactca acgccccgac gttgtagcag tgcacctttt tcctgcccca
    24241 catcagcaat ggtagaaggc atttccggct caccgacaat tgccggtttt tcgctgcgaa
    24301 agatacctgc tttctcgcga ccaatacttt cgcgatctgg ccccagccag tcggtatgat
    24361 ccagcgcaat actggttact accgcgacat cggcatcgac aatattggtt gcgtccagac
    24421 gaccgcccag ccctacttcc agaatcacta cgtcaagttg tgcctgcttg aacagccaca
    24481 atgccgacag cgtaccgtac tcgaaatagg tcagggaaat atcaccgcgt gccgattcaa
    24541 tctccgcaaa agaagcggtg tgggccgatt ccggcaattc ctgcccctgc acacgtacgc
    24601 gctcggtata acgcaccaga tgcggcgaac tgtagacgcc cactttgtac cctgccgcca
    24661 tcagaatcga ctccagcgta cggcaggtgg tgcctttgcc attcgtaccc gcaacggtaa
    24721 acacaaatgg cgctggtttc agaacgccaa gacgcgccgc gacctggctc acgcgctcaa
    24781 ggccgagatc gatagtttta ctgtgcaggt tttccagata agaaagccac gaagccagag
    24841 gcgacgcggc ttgaggagtg cgtttgataa tcatggtatc cgctgattcg ttacggtgag
    24901 aatagcaaaa gggcagagcc agtggccctg cccttatcag ttatcaggcc tcaggttcct
    24961 gatccggtac cggtggcacc actacgcctt cacgcggcgc ttcaggattc ggcgctggca
    25021 gattcatcaa cttcgccaga atgctcgcca gtttcagacg catttccgga cgacggacga
    25081 tcatgtcgat cgcgcctttc tcgatcagga attcactgcg ctggaatcct ggcggcagtt
    25141 tttcgcgaac agtctgttcg ataacacgcg gaccggcaaa gccaattaac gctttcggtt
    25201 cagcgatgtt gagatcgccc agcatggcga aacttgcaga aacaccgccc atggtcgggt
    25261 cggtcagcac ggagatgtac ggcaagccgc gctcctgcat ttttgccagt gccgcagagg
    25321 ttttcgccat ctgcatcagc gacatcagtg cttcctgcat acgtgcgcca ccagaggcgg
    25381 agaagcagat cagtgggcag ttatcttcca gcgcctgctc aacggcacgc acgaaacgcg
    25441 cacctaccac agaccccatg gaaccgccca taaaggcgaa ctcgaatgcc gcagcgacaa
    25501 ccggcattcc atacagagtg cctttcatca ccaccagcgc atctttttcg ccggtttctt
    25561 tctgcgcaga tgccagacgg tctttatact tcttggagtc acgaaacttc agcacatctt
    25621 tcggctcaag ctcgctaccc agctccacaa ggcttccttc atctaacagg ctatgcaggc
    25681 gattacgcgc tgtcatacgc atgtgatggt cacacttcgg acagacctca agattacgtt
    25741 ccagctcagc gcggtataaa acctgaccgc agctatcaca cttagtccac accccttcag
    25801 gaatgctcgc cttgcgggtg ggagtaatgt tgcttttaat tcgttcaatc cagctcatta
    25861 gggacctttc tgtctgaacc tggttcgatg ccagttttat ctttggggac gcataatgcc
    25921 atttttgccc ccaacagacc atgaatgttg cacattaaaa cataacagcc cgaaactttg
    25981 gataaaaaag tggtcgaacc gcagagttac tttttatttt gcggcgcgtg ccgctgcgcg
    26041 tttgtggcga ataaattcga aaacacctgg caatattgaa acaaaaataa tgccaacaat
    26101 catcagttta aggttgctct gaatgaaggg gagcgtgccg aagaaatagc ctgcgtaggt
    26161 aaaaagcagt acccacaaca gtgcgccaat cacgttataa gcggcgaaat gacggtacga
    26221 catgtggccc attcccgcaa caaacggggc gaacgttctg acgatcggca caaaacgggc
    26281 gagaataatc gttttgccgc catgtttctc ataaaactga tgggttttgt cgagataact
    26341 gcgacggaaa attttcgaat tgggattact gaataacttt tcaccgaaca accgcccgat
    26401 agtgtaattg accgcgtcac ccacaatcgc ggcgatcagc atcagcacca ccatcatatg
    26461 gacgttgaga tcgttggtct ccagtgatgc caacgctccg gcaacaaaca gcaatgaatc
    26521 acccggtaaa aacggcgtta ccaccagacc ggtttcacag aacaaaatta agaacaaaat
    26581 ggcataaacc cagacgccgt actccgcgac cagctctgcc agatgcacgt caatgtgcag
    26641 gataaaatcg atgaggaaat aaatcaggtc catatttgcc tatgccttgt actcgtcatc
    26701 tatcaggctg taactacgtt ggctacagcc tgaaatgttc cgagcattat tctcgttagt
    26761 ccgccagaaa tagcgggccc attggcggtt ttggaagatc atatcggtca gggtaatcca
    26821 ccgcgaccag atatagccct tccgcttttg ccgttgctgc cgccagcgtt ctgtcctttg
    26881 ccgccagcaa ctctgctatc cagctctccg gctggttgtg ggcaccgact tccatcaggc
    26941 tgccgacaat attcctgacc atatgatgta caaaggcatt cgctttgata tctaccacca
    27001 cataaggacc gtgacgcgtg acattaatat gcataacgtt gcgccacggg gtccgggact
    27061 ggcactgcac cgcacggaac gaggtgaaat cattctcgcc cagcaaacat tgcgcagccc
    27121 gatgcatccg ttcagcgtcc agcggttcgt aaaaatgggt taccccttta ctcagtaccg
    27181 ccgggcgcag ccgatgattg tagatgatgt agcgataacg gcgagccgtg gcgctaaatc
    27241 gggcatgaaa atcatcaggt acagctttaa cccaacgcac ggcgatgtca ccaggtaaat
    27301 tcgcatttac gcccaacgtc cacgcagcgt ctttgcgctg cgcggtcgtt tcgaaatgca
    27361 caacctgccc ggtaccgtgt acaccggcgt cagtacgccc ggcgcagaag acggtgatgg
    27421 gttcgttcgc cacctgggag agcgcctttt ccagcttctc ctgcacactg cggacttcat
    27481 tctgccgttg ccagccgtaa tacctactgc cgtcgtactc aatgcccagc gcaattttat
    27541 aaactggcgg ttgttgctgg tcggacatta gtacagatac tcctgcacca gtttctcggc
    27601 aatttttact gccatcagcg cgccgccaaa gcgaacgtta tcggccaccg accagaactg
    27661 aacttgctcc ggcataccgt agtcattacg tacgcagcca acagaaagat gcggcgtacc
    27721 agaagcatcc cctacctgag tcgggaattc gttctcttca gagagcacaa tatcttcgcc
    27781 ctgagcaaac gcatcacgcg cttcttctgc cgccagcgga cgcagtgctt caaagttgac
    27841 catctgggca tgaccgtaga ataccggtgc ctggacgacg cttgccgaaa tcatcagccc
    27901 ttcgtcctgc aggattttgc gtacttcgtc aacgatacga cgttcttcac gcacgctacc
    27961 ttcgctatcc ggcagtaacg gcagcatgtt gaacgccagc tgacgcccga agaaatcttc
    28021 ttcgtcaatc ggaatgccat tgagtaattt agcactctgc cccgctaacg catcgaccgc
    28081 ttttttgccc tgggcggagg ctgaaatcag gctggtaacg ctgatacgtg ataaaccgcc
    28141 ctgatcaatt agcggtttca gtgccgccag cagctggctg gtcagactgt ctggtacggc
    28201 gatgacattc cggttgcggt aatcggtcag tacaaacggg tttacttccg gcaccaccag
    28261 cggtacgtcg ggttcgagag caaacaatcc gctgctgtcg atcaccagac aacctgagtt
    28321 ggtcgcttct tcaacccagg cagcggtagc ctctttgcct gcgacaaaaa atgccagctg
    28381 cgcctgcgtc cagtcgaatt cagcagcatc ctgcacggtg attgtcttac caccaaagcg
    28441 cagttgttcg cctgcgcttt cgttacgtgc cagtgcataa atttccccaa ccgggaactg
    28501 acgttcagcc agcgtttcaa gcagggcttc gcccacagcg ccagttgcgc ccaggacggc
    28561 aatgttccag ccttcagaca tggtggttta ctccagaaat agcaaagctc cctgccaata
    28621 ttacagcaga gagcatgaag aagagattaa cgtgccggat gatgaacggc gttaaaaccc
    28681 agtttacaca gcaatgatgc cgcgctggcg tcatcacaaa tcacatacag agatgaccat
    28741 tcacggcgct caagatagtt tttgcgcagc ttatcgaact cacccggtat tccggcgact
    28801 ttacgcagcg gtgcgtcatc gcggcgcaca tcatacacca aatgcaccag cctttttagc
    28861 gtcggttgat cgagcggacc atgcagcgta atgcggccaa actctggcgc gggcagcaac
    28921 gtatccagcg caacgtgttg ttcatgccca ataagcttgc tataggcttc aaacacttgc
    28981 gtagtaccgc gtgctttacc ttccagggta tagcctgcga tatgcggtgt gccgatatcc
    29041 acttttttca gcaattccac gttgagttcc ggttcgcctt cccagacatc cagcactacg
    29101 cttaacttct ggccttcgtt cagacaggtc aatagggcag tattatcgac gactgcgcca
    29161 cggcaggcgt taatcagaat cgctcctggt ttcaggctac ggatcagttt ttcatccgcc
    29221 agatgcagcg ttttgtacgg cccgtctttg aagagtggcg tatggaaagt cagaatatcc
    29281 gcatgctgaa ctaattcatc cagcgagcgg aaatccccct catccccgcg gtcggcgcga
    29341 ggcggatcgc aaagcaaggt tgtaatccct aacgcttcca gtcgcgcctg taaacggcga
    29401 ccaacgttac caacgcccac gatccccact gtacggtcgt gcagtgaaaa tccatcgcgt
    29461 tcggcaagca tcagcagtga ggagaaaaca tattccacca ccgcaatcgc attacagcca
    29521 ggtgcagcgg aaaaaccaat tcccgcctgc tttaaccatg cttcatcgac atggtcggtc
    29581 cccgcggtgg cagtgccaac aaatttaatg ggttttcctg ccagcaaaga ttcattcact
    29641 ttcgtgaccg aacgcaccat aagcgcatcc gcgtctgcca gttgagcgac aggaattgga
    29701 cgcccgggaa ccgcggtcac ctcacccaaa cggctaaata agtcgcgggc ataaggcata
    29761 ttttcatcaa caaggatttt cacgtttgtg ttacctgtat gagacgagag ttaaccagac
    29821 aagtgtgcca taatctcgcg gccaggcata cttgcgaaga tttcaggtat aaggatacgt
    29881 aatgatacaa cctatttccg gccctcctcc tgggcaacca ccaggccagg gagataacct
    29941 gccgtctggc gcgggcaatc agcctttatc cagtcagcaa cgtacttcgc tggaaagctt
    30001 aatgacgaaa gtgacctcac tgacgcaaca acaaagagca gaactgtggg cgggtatcag
    30061 gcacgatatt ggtctgtcgg gagattcacc gctgctttcg cgtcacttcc ctgccgctga
    30121 gcacaatctg gcgcaacgtc tgctggccgc gcaaaaaagc cattctgccc gccagctttt
    30181 agcgcaatta ggggagtatt tacgtctggg gaataatcgt caggcggtca cggattatat
    30241 ccgtcataac tttggtcaga cgccgctgaa tcagctctca ccggagcaat taaagaccat
    30301 tctcaccctg ttgcaggaag ggaagatggt tattccgcaa cctcagcagc gcgaggcgac
    30361 cgaccgtccg ttattaccgg cggagcacaa tgcgctcaaa cagctggtga ccaaacttgc
    30421 ggcggcaacg ggagaaccca gcaagcagat ctggcaatcg atgctggaac tttccggggt
    30481 gaaagatggc gagttaattc cagcgaaact gtttaaccat ctggtgacct ggctacaggc
    30541 gcgtcagacg ctaagccagc aaaatacgcc gacgctggaa tcactccaga tggcgctaaa
    30601 acaaccttta gatgccagtg aactggcggc gttatcggca tatatccagc aaaaatatgg
    30661 cctttctgcg caatcatcgc tttcttctgc ccaggccgag gatattctta atcagcttta
    30721 tcaacggcgg gttaaaggga ttgagccgcg tgatatgcaa ccgctgctta atccttttcc
    30781 accgatgatg gacacgttgc aaaatatggc aacgcgtccc gcgctgtgga tactgttagt
    30841 cgcgattatc ctgatgctgg tctggctggt tcgttagccc cgacgaaatg acagtatcgt
    30901 gacaataatt cccagcaccg cagagatcgc cccggcaaga aataccgaag agtaaccaaa
    30961 cgtggtcgcc agcattcccg ccagcggccc ggagacgccg agggcgatat cctgaaacgc
    31021 ggcgtaaccg cccagtgcgg tgccgcgaac ttgtgagggg acgcgtttaa ccacctccac
    31081 gcccagcgca ggaaagataa gcgaacatcc ggctccggtt aacgccgcgc ccgctaatgc
    31141 gacccacgca ccaggggctt gccagagcag caacaagccc accgtttcta caagcagaga
    31201 gacgatcgcc actttcacgc cgccaaaacg gtccggcatc cagccaaaca tgacgcgcat
    31261 cacgacaaat gcgccgccaa acgcggtaag agtaaagccc gccatcgccc atcctttact
    31321 ggcaaagtag agcgaaacga aagtcccgat aaccgcaaaa ccaacgcctt gtagtgccag
    31381 acctaaccct ggtttccaga taagcccgac aacgctccac agcgatggac gttctcccgc
    31441 cagggccggt actttgcgca ctgtgccgtt acaggcccac gccagtaagg gtaatgccat
    31501 tgtggtgagc gccagtgcgg caaaaccgta atggctatga atcaacaggc caagcggcgc
    31561 accaacagcg agggcaccgt aaatcgccat tccgttccat gacatcactt tgccggaatg
    31621 ttttggccca acgatgccta atccccaggt cagagcgccc gtcagtaact ggctttcacc
    31681 aaagccaaga atcaaacgcc cgacgaccaa cagggcaaat ttgaacggtg cggagacggg
    31741 caaaatcgcc gccaacagca gcgcgccgcc agccagacca caagctaaca tcccctgaag
    31801 cgccgaacgt tttgcgccat attgatcggc cagtcgcccg gcgtaaccac gcgtcagcac
    31861 cgtagccaga aactgaatgc cgacggcaat accgaccatg gtgttgccat agcccagttc
    31921 atgatgaaca aacagcggga taaccggcaa cggcagccct acggtcatgt aggtgagaaa
    31981 aaccgcaaaa gcgatgcgga agagcgaaaa attggcagaa gatcgtgttt cggtttggct
    32041 tacagcagtc atgcattact ccagaatgca gcgcaaggcg aggaatttcc ccgtctcatc
    32101 tctctggttt cagggttacg gtgcgttggc aggatttaac gcgtacgtct tttcagaagg
    32161 aaatcgacaa agcgggaagt ttgcctggaa caggcggcga ttgtcaataa tgtgaaaaag
    32221 ggaaccatca ggttcccttt tgcgttagtg tcggatgccg cattggcgcg taatgtcgga
    32281 tgcgacgctg gcgcgtctta tccgacctac tccgaattaa tctttcagct tgcgcattac
    32341 cagcgtggcg ttggtgccgc cgaagccgaa gctgttagac ataactgtgg tcagttcgcg
    32401 atcggtcgtt tcggtcacga tgttcagacc cgcagcctgc tcgtccagct cttcaatgtt
    32461 gatgctcggg gcgataaaac cgtgttccag catcagcaga gagtagatag cttcctgtac
    32521 gccagcagcg cccagagagt gaccggtcat tgctttggtt gcagaaatcg ccgggctctt
    32581 atcgccgaac acttcacgga tagctgccag ttctttcacg tcgccaaccg gagtcgaagt
    32641 accatgagag ttcaggtagt cgattggggt atcaacaccg tgcatcgcca tcttcatgca
    32701 gcgcactgca ccttcgccag acggagcaac catgtctgcg ccatcagagg ttgcgccgta
    32761 gccaacgatt tcagcataga tgtgagcacc acgcgccagc gcgtgttcca gctcttcaac
    32821 cactaccata ccgccaccgc cagcgataac gaaaccgtca cggtgagcgt cgtaagtacg
    32881 ggaggctttt tccggggtgt cgttgtattt agtagacagc gcacccatcg cgtcgaattc
    32941 gcaagccatt tcccagcaca gctcttcgcc gccgccagca aacacgatgt cctgtttgcc
    33001 cagttggatc tgctctactg cgttaccgat acagtgtgcg gaagtcgcac acgcggagct
    33061 gatggagtag ttaacgccgt gaattttaaa cggcgtggcg aggcaggcag aaacgccgga
    33121 tgccatcgct ttggtgacca catacgggcc aaccgctttc aggccgcgcg ggccgcgcat
    33181 tgcgtcagcg ccgaaaacct ggaaacgcgg ggagccgccg ccggaacctg caatcaggcc
    33241 aacgcgcggg ttattctggt aagcttccgg ggagaggcca gcatcagcaa ttgcctgctc
    33301 catagaaagg aatgcataaa tggatgcgtc gctcataaag cgcacaactt tgcggtcaat
    33361 gaggccagtg gtatccagtt ttacgttgcc ccagacgtgg ctacgcatgc cggaatcctt
    33421 cagctcctga gagaaagtga tccctgaacg tccttcacgc agagatgcca ggacttcctg
    33481 ctggttatta ccgatgctgg aaacaatgcc caggccagta atcactgcac gtttcattca
    33541 atacctctgt aagtcgcaca tagagtaagt ttcgaatgca caatagcgta cacttgtacg
    33601 ccgaacaagt ccgatcagcc aattaataga gaaatttgcg cagcctgaca cacatcgcta
    33661 agatcgagcc accgcctgta agacgagtaa cttacgtgaa acactactcc atacaacctg
    33721 ccaacctcga atttaatgct gagggtacac ctgtttcccg agattttgac gatgtctatt
    33781 tttccaacga taacggactg gaagagacgc gttatgtttt tctcgggggt aaccatttag
    33841 aggcacgttt tcctgaacat ccacatcctc tgtttgtggt agcagagagc ggcttcggca
    33901 ccggattaaa cttcctgacg ctatggcagg catttgatca gtttcgcgaa gcatatccgc
    33961 aagcgcaatt acaacgctta catttcatta gttttgagaa atttcccctc gcccgtgcgg
    34021 atttagcgct ggcgcatcaa cactggccgg agctggcccc gtgggcggaa cagcttcagg
    34081 cgcaatggcc tttgcccttg cccggttgcc atcgtttatt gctcgatgaa ggccgcataa
    34141 cgctggattt atggtttggc gatataaacg aactgaccag ccaactggac gattcgctaa
    34201 atcaaaaagt agatgcctgg tttctggacg gctttgcgcc agcgaaaaac ccggatatgt
    34261 ggacgcaaaa tctgtttaac gccatggccc ggctggcgcg tccgggcggc acgctggcga
    34321 cctttacgtc tgccggtttt gtccgccgcg gtttgcagga agccggattc actatgcaaa
    34381 aacgtaaggg ctttgggcgc aaacgggaaa tgctttgtgg ggtgatggaa ctgacattac
    34441 ccctcccctg ctccacgccg tggtttaacc gtacgggcag cagcaaacgg gaagcggcga
    34501 ttatcggcgg tggtattgcc agcgcgttgt tgtcgctggc gctattgcgt cgcggctggc
    34561 aggtaacact ttattgcgcg gatgaggccc ccgcactggg tgcttccggc aatcgccagg
    34621 gggcgctgta tccgctttta agtaaacacg atgaagcgct aaaccgtttt ttctctaatg
    34681 cgtttacttt tgctcgtcgg ttttacgatt tattgcccgt taaatttgat catgactggt
    34741 gcggcgtcac gcagttaggc tgggatgaga aaagccagca taaaatcgca cagatgttgt
    34801 cgatggattt acccacagaa ctggctgtag ccgttgaggc aaatgcggtt gaacaaatta
    34861 cgggcgttgc gacaaattgc agcggtatta cttatccgca aggtggctgg ctgtgtccag
    34921 cagaactgac ccgtaatgtg ctggaactgg cgcaacagca gggtttgcag attcattatc
    34981 aatatcagtt acaggattta tcccgtaagg atgacggttg gttgttgaat tttgcaggag
    35041 atcagcaagc aacacacagt ttagtggtac tggcgaacgg gcatcaaatc agccgtttca
    35101 gccaaacgtc atctctgcca gtatattcgg tggccggtca agtcagccat attccgacaa
    35161 cgccggagct ggcgaaactg aagcaagtgc tgtgctatga cggttatctc acgccgcaaa
    35221 atccggcgaa tcagcaccat tgtattggtg ccagttatca tcgcggcagc gaagagacgg
    35281 cgtacagtga tgaagatcag cagcagaatc gccagcggtt gattgattgt ttcccgcagg
    35341 tacagtgggc aaaagaggtt gatgtcagtg gtaaagaggc gcgctgcggt gtgcgttgtg
    35401 ctactcgcga tcatctgcca atggtaggca acgtgcctga ttatgacgct acactcgtgg
    35461 aatatgcgtc gctggcggag aagaaagatg aagcggtaag cgcgccggtt tatgacgatc
    35521 tctttatgtt tgctgcttta ggttcgcgcg gtttgtgttc tgccccgctg tgtgccgaga
    35581 ttctggcggc acagatgagt gaagaaccga ttccgatgga tgccagcacg ctggcggcgt
    35641 taaacccgaa tcggttatgg gtgcggaagt tgttgaaggg taaagcggtt aaggcggggt
    35701 aatctgctct ggcattgttt gtcggatgcg gcgtaaacgc cttatccgac ctacgcgtta
    35761 cctgtaggcc tgataagacg cgataagcgt cgcatcaggc atggtgctcc agacgtcaca
    35821 acttactgct gtgaggcctg ctgaaacagg tgttcccaca tatcggtcac cagcgcctgg
    35881 tcacgcggcg acaattcacc ggcaccaatg gctttttcca gactctggct aacggttgta
    35941 tgtaccgcct gagcggagtg gtcgtcacca ctttccagtt ctgcgatggc taatgtcagg
    36001 tggccacgca aatacccact ggcaaacaac tcatcatcac tggcatggtc aaccataccg
    36061 tcgattaatg ccagaatgcg tgattcaaac tccgcgatca tcttctttcc tcattgtaaa
    36121 acgtggcgct ggcttcagtt gagcgcttcc ggccacggga actgttccgc cgtaagttcc
    36181 ggcgtgtgat aataattttg tagtgcttta atgaagcgtg ccggacgttc gggaatgccg
    36241 tttgccagat aatccatcac ctgcgcatgt acccgccgtt gaaacaccac gcggtccggt
    36301 tcgaaatccc cttccagatt gtcgcagcta acattaaacg gatatcccgc tgccacgcag
    36361 aacaaccagt ccagcgcctg cggcttcact tcaacatctt caaactggct ttgtgtctgg
    36421 gcatcgcgtc cgtccgggca ataccagtag ccgaaatcaa ccagctcacg gcgcgctttc
    36481 ccggcaatac accagtgcga aatctcgtgg atggcgctgg cataaaagcc atgagcgaag
    36541 acgattctgt tatacggtac ttccgcatca gcaggaagat agatcggttc gtcgtcgcct
    36601 ttaatcagac gggtattaaa ttcatcggca aagcagctat taaaaatctc aatcaactgc
    36661 tcatagtggt gtgtactgtt cattagttca tccccaacca gtggaggatc tcctgtccat
    36721 ggctatcgta aagtaatttg gcactcatca ccgccgagac gataacgatc atcgggcgga
    36781 tcagcttttg tcctttgctc aacaccagtc ttgaacccat gcgcgcgccg aggaactgcc
    36841 ccaccagcat cacaaagccc gtcgcccaaa tcactttgcc gccgagaata aacagcagca
    36901 gaccgccaat gtttgacgtt gcgttaagta atttggcgtg agcagtggct ttggcgaggt
    36961 tgaatccgca cagcgtaacg aaggccagcg cgtaaaacga tccggcagcc gggccaaaaa
    37021 atccatcgta aaaaccgacg cagccccccg ccaccagcgc aaatggcagt ccatacatcc
    37081 gacgctggcg atcttcttca cccagctttg gcatcagcaa gaaatagagg ccgatacaaa
    37141 tcaccagaat aggcaaaatc tgccgtaaga catcggcctg aacatactgc accagtagcg
    37201 cgccgctcat tgagccgaca aaggtcatgg cgatattgag tttttgatcg cttaaactaa
    37261 ccactttacg gcgaataaag tagatagtgg cggaaataga gccaccgcag gcttgcagtt
    37321 tattggttgc cagcgcgtta gcgggagaca tccccgccgc catcaatgcc ggaatggtga
    37381 gtaacccacc gccaccggca atcgagtcga taaatcccgc cagcatggcg acaaaaaaga
    37441 gaactcccag cagcagcggg gaaaccataa acaggctatt aaacgtttcc attagatcac
    37501 gtgctcatcc agtagcgcct ggcaggaagg cggcaacgga ggcggtgtct tcttctcagg
    37561 ctttgttgtt cccggttttg gaggttcaaa ccagctttgc agttctgccc cgcaaccatc
    37621 gcctggtggc ggtaaaggtt gatcctcaca ctccagacta tcggcaggac aacgtaatcg
    37681 tacatgcata tgcgcgcgat gctggaacca gggtcgcact ttgcgcaacc agtcgcgatc
    37741 ggtgcccgca tcaaggcaaa gttgttgctt aatcgccgga ttaacaaaaa tgcgcgtgac
    37801 gtctttatcc tgggcggcga gtttgatcaa gctgaaaatt tctggcttcc acagcgtcgg
    37861 gacaacgtgt ttaccgtcgc gggaaactaa atctaacgct tgcgggcgca agagttgcgc
    37921 ggaggtccag cgtgttttcg gcagttgcag gaagatatcg acatccagtc cggtctggtg
    37981 gctggcgtga ccgccgttga aacgaccacc agcaggcatc cccatatcgc caatcagcac
    38041 cgtacccatg cccagattgc tcacctggcg actcagacgc tggataaaca tcaccaggtc
    38101 tgggtgaccg aaatagcgac gctgatcggt acgcatgacc tgataatgtt cggactgtat
    38161 cggcaacgtg tcagcaccga tgatacagcc attagaaaaa ctgcctatcg attgtgcgct
    38221 acccggcaca ggttgggtta ttttttgcca cggcgtcgct gccaggctgg cgctactggc
    38281 aagcagagcc agcagcgcaa tcgcggtttt gttcattttt taccagcgtg gaatttcagt
    38341 cttcacatcg gcattttgcg cccgctgccg taacaggtga tccatcaaaa cgatcgccag
    38401 catcgcttct gcgatcggca ccgcgcggat cccaacacaa ggatcgtgac ggcctttggt
    38461 gatcatctca acttcttcgc caaagcggtt aatagtgcgc cccggcacgg taatgctgga
    38521 ggtcggtttc agcgccatgt gggcaatgat ttgctgcccg ctgctgatac caccaagaat
    38581 gccgcccgca tggttgctct ggaaaccgtc tttggtgatt tcgtcgcggt tctggctgcc
    38641 acgcagcgct accacgtcaa aaccatcacc aatttccacg cctttcaccg cgttaatgct
    38701 cattagcgca tgggcgatgt cggcatccag gcggtcaaag accggctcgc caagtccggc
    38761 gggtacgcca ctggcaacga cggtgacttt cgcaccaata gagtcgcctt cttttttcag
    38821 cgcgcgcatc agttcatcta acgcgtcgat tttgtccggg tccgggcaga agaatggatt
    38881 ttgctcgacc tgagaccagt ctttgatttc cagcggaatg tcgcccatct gggtcaggca
    38941 accgcgaatc tcaatgccaa atttctcggc gagatatttt ttggcaatcg cccctgctgc
    39001 aacgcgcata gcggtttcac gggcggaaga acgtccaccg ccgcgataat cacgcaggcc
    39061 gtatttttgt tcgtaagtgt aatcggcatg acctggacgg aaaacgtcct taatcgcact
    39121 ataatcctga gaacgctggt cggtattttc gatcaacaat ccgatgctgg tgccagtagt
    39181 aacaccttca aaaacaccgg agagaatttt gacctgatcc ggctcgcggc gctgggtggt
    39241 atagcgcgat gtcccagggc gacgacgatc aaggtcatgt tgcaggtccg cttccgtcag
    39301 cggaatgcct ggcggaacac catcgacgat gcagccgagc gccagcccgt gcgattcgcc
    39361 gaaggtggtt acgcgaaaga gttgtccaat tgtgtttcca gccatcacgg ctccgttatt
    39421 gttgtgtttg cgtgtttact taatctttat aaatcgcgaa atgttctcgt gcggcaataa
    39481 gctgctcttt agtgagcata aacacaccat cgccgccgtt atcaaactcc agccaggtga
    39541 acggaacatc cggatattgt tccataagat gtaccatgct gttgccgact tcacaaatca
    39601 gcacgccatc atcagcgagg taatctgccg cgtttccgag aatgcgacgc gtcagtttca
    39661 ggccgtcggt gccagatgcc aggcccagtt ccggctcgtg gcgatattcg tttggcaggt
    39721 cggacatatc ttccgcatcg acatacggcg ggttagtgac aatcaggtcg tactgcactt
    39781 tcggcaagtc gcggaacaaa tcggaccgaa taggaatgac gttgtggatc agaccgtgtt
    39841 cttcgatgtt ctgttcagca accgccagcg cgtcgggaga gatgtccacc gcgtcgactt
    39901 ccgcttccgg gaaggcataa gcacaggcaa tggcgatgca gccgctaccg gtacacatat
    39961 ctaaaatgtg ctgcggttgc ttgctgatga gtccggcaaa tttattgttg atcagttcac
    40021 caatcggcga gcgcggcacc agcacgcgtt catcgacgta aaattcatgg ccgcagaacc
    40081 aggctctgtt ggtcaggtaa gccaccggaa tgcgttcgtt gacgcggcgg atcacgcgct
    40141 caacaatacg gtgtttttcg ctggaggtca gacgcgcggt gcgcatgtct tccggaatat
    40201 ccagcggcag gtagagtgaa ggcaacacca gttgcacggc ttcatcccac gggttatcgg
    40261 tgccgtggcc gtaccagata ttcgccgcgc tgaagcggct caccgaccag cgcaacatgt
    40321 cctgaatggt ttgcagctca tttactgctt catcaacgaa aattttatcc acgtattcct
    40381 ccagggcatg atcgcaataa tttcggcggc tagtttgcca tgaagatgac gataaatcag
    40441 cattcacgcg cggtgagtga ggaaaaatac gtttaaaacg atcgattgcg ctacgagtcg
    40501 ggtaaactgt aggaaaatta gaaatagaga aagataaatg aaaaagaaaa caacacttag
    40561 cgaggaggac caggcgctgt ttcgccagtt gatggcgggt actcgcaaga ttaagcagga
    40621 cacgattgtc caccgaccgc agcgtaaaaa aatcagcgaa gtaccagtaa agcggttgat
    40681 tcaggagcag gccgatgcca gccactattt ttcggacgag tttcaaccat tattaaatac
    40741 tgaaggtccg gtgaaatatg ttcgcccgga tgtcagccat tttgaggcga agaagttacg
    40801 ccgtggcgat tattcaccgg agttgtttct tgatttgcac ggtctgacgc agctacaagc
    40861 caaacaggaa ctgggggcgt tgattgccgc ctgccgccgt gaacatgtgt tttgtgcctg
    40921 cgtgatgcat gggcacggga agcatatttt gaagcagcaa acgccgctgt ggctggcgca
    40981 acatccacat gtgatggcat ttcaccaggc accaaaagag tatggtggtg atgcggcttt
    41041 gttggtgttg attgaagtgg aagagtggct gccgccggaa ttgccctaat aaatattgcg
    41101 gtataaacgt cttctccgac caggatactg accggagaag aattaaccct acaactcatt
    41161 caaaatgtac tggaaacgac aggtggcatc gattggctgc tgactgctgg tgtcgatccg
    41221 tatttgcata tcatgcagtt gcttatcggt aattggatgt gctaccggcg ttactgtgac
    41281 tttgctgtcg tcacaccccg acgtgctgaa tgtgatcata tacgacataa agcgacaata
    41341 agcgccacga tcgtccattc ggcttccatc acacacccgc ccgtcgcgca tcaggtaagt
    41401 cgagagcgtt tgtgttatga ctccccccgt cgattgcagc gttagcatct tgttatggag
    41461 gacgtagttc tcattccagg agatatcata ggggccaacc ggctccgttg ggcaccgggt
    41521 ttgttttgct gatggaccaa tgtaagtata acctctcgca gcagtactca ccgtgttggt
    41581 actgaccaac cacgggcacc cgtgagtttc accatgcacg atgatatcga cccccagatc
    41641 aacacatgac catccatccg taatccctgg gcaattggag ttatccacag tattactctg
    41701 atgagtgatg ttcatcgttg gtgctgatcc cggtcccgtc caaaccgtgt tagggatatt
    41761 ccccaaccac aacgtatatc catcctgtgc atattcgcca taatagaccc cttccggcgt
    41821 caagacatcg atacgaaaga caacttttgt tgtagccccg ttaccccaaa atccggtata
    41881 agtcttcaca tccctgaatg tgacgtccgc ccaggcggtt gcactcagta gcccggtcag
    41941 cagtaaaaaa aacagtccgc tcattttttt catgttaaat atactcaaac gtcgcagtga
    42001 gggaggccgt aaagtcaccc atcgtcacat cccgcccgct ttttgcctgt agccaggcat
    42061 taaaatgcag atcattgttg ccgctgctca gcacaaatgt cgccccgctg gtattgttga
    42121 ttagcacagc agtgccgtcg gtcttttcca tgccaatccc cacaccttgt gctgtcgaag
    42181 cggcatccag cgccagaaaa ccgggctgct cgctgtcttc cgttccggta agtgtcaccc
    42241 gaacctcata ctgagcaggc cctttgcaat ctttaagctg aaacaccacc ggtacgcgcg
    42301 cagattgccc ggtcaccatc agatctctac ggctgaccgt ggggaaatgc acttccgcca
    42361 gcacctcgcc ctgaaccacc agcgtgcagg acttactgag taaattgccg tagaaatgca
    42421 ggttgtctgc cgcctgaaca ttcggcgtca gcagcaccgc ggccagcgca gccgcgcagt
    42481 gaaatatccg ttttaggctc attggtaatc cacctgtaat gttgcccagg cagaaaaggt
    42541 tccttcgctg agtgaagcat cactggcttt caccggtaca gcttgcagcg ttggcggcgt
    42601 tgacaggttg attttcagcg gcgtacccaa cgtgaacggc tggccatttt gttgcagctc
    42661 aatccccagc ccggtgacgt ttgtctcaat agccgcgtta tcgtagctgg tctggctgcc
    42721 cgtccagctc agcgtcatct cccaggcatc gtcgcgcacg tcgggatcgc atgtaatggt
    42781 atagggcaca ttctggcgga agttattgcc gttgatgttg tcgataatga cgtcacgaaa
    42841 ctcaacttca acggttttcc cgtcactgat ggcacaggcg ggcggcgaaa ccaatgtgcc
    42901 atgaaatgtg atatcgctat cggccgcctg tgcaataccg caataacaac cgaataagca
    42961 gagcgcaaat cgtttcattg atactccacc accattgtca tggttgcgct aaactctgat
    43021 gccgtaagct gtgtgccgct ttgtttcacc ggcacggctt cgaaacccgg gcgcgaatta
    43081 acgttaaacg gcagccagtt attacccgcc aacgcaaccg gcgcatggct ggacgcatcc
    43141 tgtatgcgaa tgccaaaacc attgatgccc gtactgagga ccgtttcacc gttaatggtg
    43201 gtggtggtcc cctgtaactg catctgtagg tcatcgctga cgctgttcga acagttcagg
    43261 gtgtaaccaa caggctgccg atagttgctg ccgtcgatgt ttttaataat gacattgcca
    43321 aactccaccg cgctgccttt taccgtacag ggcggcggtg catccaccag tatacgaagc
    43381 gttaagttga ccgttttact atcggcccag gcggagccgc aggccagtaa caccatgcca
    43441 gcgacgggta ataaaactcc tttcatgctg gatctcctgt cattagcctt ttaggctttg
    43501 agcttcatcc accttgcagg tgtctccttc acaacggaag accagcggta aacgtgcgcc
    43561 gtagtcgttg atgtaggtca gcaccggagc gctgttcatt tttgccttta acggttgtga
    43621 cgttttcggc ggcatcacca gtggtttaaa gcccgcagca gttagcccct ttttctgcgt
    43681 actggcatcg ctgatgatga cgtggtacgg cgtcgggtta ttgacgatat agtcctggcc
    43741 gctgcgcgtg agtgtgacct taaactgcca cggttttctc atgtcaatct tctccagcgc
    43801 ctttggtcgc cagaacagct tgatgcgggt ttgcagcgca atttgcaggg tgttggcttt
    43861 cccggacttt ggcgggatct cacgcacatt gtagtagaac aggctttcac ggtcagacgg
    43921 cagcgtgtga atgtccggca gcgcctgaat cttcacctga ccgttcatca tggcgtcaat
    43981 acgctgcacc ggcggcagta ccgccagcgg cgaagtgatt ttgttgccct tctcgtcttc
    44041 cagccagctt tgcgccagat aaggcagctt ttcgttattg ttgcgcaggg ttacgcttat
    44101 cgatttatca ctttcgttaa acaccagacg ggtgcgatcc ggagtgactg atgcgtgcgc
    44161 cgccaggttg gtggtggtca acagtaccgc cagcgtcgtg ctgaccacca ttgaacagga
    44221 taatttataa aacattgatt gttccttaat catattattg agtggctgaa attgacgtcg
    44281 gcgcttcaga tggcgtgacc tgccgagtct ggtcctgaat aacgggctta atttccggcg
    44341 ctaaagaatc gggggctgtc gttccctttt gttcacacgg caacaacagg ccgcggaaca
    44401 gatcggcagg tagcggcttc ggcaatacga tctcgcattg tgcgctgcct tcccagaaca
    44461 ccatcatatg ctcacccgca ttgatccccg ccagatagac attgccttca tcatccacaa
    44521 tgccaacctg ctgctgctcg tcgtttttta cttccgcgcc aaacggcggg tagctaccgt
    44581 cacgcaaccg cagtaccgcc atcgcttttt gcccgctgat cactttgaat ttacgatagc
    44641 cgattgcgcc ttccgtcaga gtcgcctgca ccaccgactg ggtggcttcc gcatcttccg
    44701 gcaagttgtt taaatctata tacgcctgat tgcgatagta gttgttaata tcggcgacca
    44761 ccgccttgcc aaacatattg gtgtacaccg gcgcgccgtt gctttcgacc ggcacgttgg
    44821 caataccgtc ggcgtcaatc agcaggcgtg tgccgcccat gttttgagtg cgatgcagcg
    44881 ccccaccgtg cgcggtcagc gttgccccgc cctgtaaggc gatccccgcc gaacggtatt
    44941 ctccttcatg gtagttggcg ctgagatcta ccttcgccaa cgtgccgtcg tggctcagat
    45001 aaccatccac gctaccgtgc tgttcgctgg tgccgacgtt aatctggtag tgcgttgcgt
    45061 catcgatgcg attaaagtag ccgacctgac tgctgtccga cccgctaccg taagagccgt
    45121 tgtaggtcac ggtgctgctg tcgctccacg gaatgctcat gctgaggtac attcccttat
    45181 ccgtattatc gtcatattcg tagcgatagc cggtcaccga gatgctcata ttgcgaatgc
    45241 tccccatatt aaaatagtgg gaaaacatca ggttatagtt tgtctgttcc gggcgatccc
    45301 agtaagtacg atgggagtag ttgagataga ccgagacacc cgctgcggca aagttctggt
    45361 tatacgtgat cgtatacatc tctttgtcgt ttccggtccg cgccatgtcc gactggctcg
    45421 cgtccagata ctcgctcata gtcataaagt tcttttcgga gaaacggtag cctgcaaagg
    45481 tgacgcggct gttaagttcg tcaaagtctt tggcatagct cacgcgaaag gagttgccgt
    45541 ccagttttcc tttgccgtat gcgctgtcat gatccaggtt gacgtgcgag tgagtcacat
    45601 cgaacgccag cgcgccaaac tgtgcgaggt cgcgccccac ccccatcgcc gccgactggt
    45661 agtgctcatc tgccagcgcg ccaccgtaaa gcgaccagcc atctgccacc ccccatgatg
    45721 cttctccgcc ggaaaaaaat ccgccttcgg tcttgtggtt ccagtcttcc ggacgcccca
    45781 tcatcacttt gtaacgcacc tgcccctgac gcgtgaggaa tggcatggat gcggtggtga
    45841 cgtcatattc ctgcacctga ccattctgtt cttcaacacg gacgtgtagt gtgccagaga
    45901 cagaatcgcc gatatcctga atgcggaatg gcccggcggg aacctgggtt tcgtaaagta
    45961 cccggcccat ctggctgatg gtcacttttg cgctgctgtg cgccacgcca gaaacatctg
    46021 gcgcatagcc gcgcagattg ggcggcagca tctggtcatc ggtgctgaca ctgctgccga
    46081 tatagttaaa gccgtcgaaa atatcggaat tgagataatc ttctcccagc gacagcttcg
    46141 cttttaaaga gggtaaagct cgccaggcgt aataacggct ccagtcccag tttttactcg
    46201 ttgtactgtt actgctgtca tcttcatcgt cgttgctgcg ggtgtgctga taatcacttt
    46261 gccagtctgc acggaaacgc catgccccaa ggtttgcccc aactgtaccg ttaccgctga
    46321 tatcatgtga gtcctcgccc ccttgctcct gatggcgagt ttgcgcattg aggctgtagt
    46381 cggcaatcag cccagaaata ccatcgtccc agcgtgaggg agggtcccag tcgctgctgg
    46441 tatattcgag gtaagcctgt ggcactgtca gcagcaaagc cgactggctt aaatcattct
    46501 cgacttccat cccgtctaat tgccccggtt taaggcattc atcgttgtgc gtccactgca
    46561 ggctttttgc tatcccttct ttcagcccca gcgccgccac taactcaggt gtcaggcagg
    46621 cataagtttt tgttggatcg ttttcagaga cataccaatt aatgtcgtat tcatcagaaa
    46681 gggattgttt atttataaat acacgtaaat tatatttacc cgcgtcgaca tacccttttt
    46741 ttgaaaactt accgagatca attttcgtgt cgccctttaa ctcaaggaaa cgggggtcaa
    46801 attgaatgga atcatcagcc catgcattga ctgatccacc agagattgcc agcgcaatat
    46861 agcaggcgat tccccgcagc cgaaaatttg agtgattagg catacacata tccgtttgtg
    46921 aaacagtcgt aaatccgttg tgcgttgaat aaccccacag cagaacgctg tggggttgtc
    46981 acatcagaga taggtaatct ggaatgtggt cagggtttcg aactggccga gatccggcgc
    47041 atcggtttca cccaccagcc aggctttaaa gttcagcgtt tgcttgtctt tacccttgct
    47101 agttgaagca tccatcacga ttggctgaac aatcttttcg cccactttat aacctttgcc
    47161 atgggtatcg ccgattacca ggctcacgtg gttcatggca acaccgctgt caacattgaa
    47221 taacgcatag ttatctgcgt tggctggccc cgcgtagtta gtgccggtga acgtggtctc
    47281 catgtttgat tcagtggtaa acacgcaatc ctgtaaatgg atctggaaat ctttcggtgt
    47341 ggtagtgccg ccgccagtca gtttagccgc accgatatcg cccatatcga cttccagttt
    47401 atgatcgtct ggaacgatgg agcacgggga gtcttcaata gtgccgtaaa aacgtgcggt
    47461 accgttgtta cctgcggcaa aagcagaact ggagacgact gcgcccatga cca
//
LOCUS       DAPOXO010000032        47082 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPOXO010000032 DAPOXO010000000
VERSION     DAPOXO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47082
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.032"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            136..411
                     /locus_tag="ROH59_002194"
     CDS             136..411
                     /locus_tag="ROH59_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804674.1"
                     /translation="MPTVLSRIAMQLKKIAWIIPVFMVSGCSLSPAIPVIGAYYPGWF
                     FCAIASLILTLITRRIIQRTNINLAFVGIIYTALFALYAMLFWLAFF"
     gene            430..1461
                     /gene="mdtN"
                     /locus_tag="ROH59_002195"
     CDS             430..1461
                     /gene="mdtN"
                     /locus_tag="ROH59_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HDX4804675.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVSDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSVNATVEKARAAAKQASDTLRRTEPLLREGFVSAEEVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGA
                     SAVANLEPQ"
     gene            1461..3512
                     /gene="mdtO"
                     /locus_tag="ROH59_002196"
     CDS             1461..3512
                     /gene="mdtO"
                     /locus_tag="ROH59_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313090.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HDX4804676.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAITQMHQALNDRLDDAISHLTDSLAPLPETRIEREAL
                     ALQKLNVFCLADDANWRTQSAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAIAEGQCWQSDWRITESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     TKPPSIVADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGALGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVVLERQLD
                     SEERALLIERSQTVIRQGRDILHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPAKEQAQGAT
                     Q"
     gene            3509..4975
                     /gene="mdtP"
                     /locus_tag="ROH59_002197"
     CDS             3509..4975
                     /gene="mdtP"
                     /locus_tag="ROH59_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HDX4804677.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLNGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYAMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAISAHNAALAETAAVELSLTTGVAQLYYSMQASYQMLDLLEQTRDVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIAAVKGQITETRESLRALIGAGASDMPE
                     IKPVALPQVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDSIHLDTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAAPVVEKK"
     gene            5173..7320
                     /locus_tag="ROH59_002198"
     CDS             5173..7320
                     /locus_tag="ROH59_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5590..5592,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HDX4804678.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAESAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRVAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            7695..9263
                     /locus_tag="ROH59_002199"
     CDS             7695..9263
                     /locus_tag="ROH59_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX4804679.1"
                     /translation="MIKKLLPLLVLSTISATTVAATPPNTLVVAQGLDDIVSLDPAEA
                     NELSSIQTVPSLYQRVVQPDRNDPTKITPILAESWQADPAAKTLTIKLKSDAKFASGN
                     PVRPEDVIYSYVRAVTLNKSGAFILNVLGWQPENIASQLKKIDDHTVQVQWSADVSPA
                     LALNILSTPIASIVDEKLVAPNAKNNDFGNEWLKMHSAGSGAFKMRTYQPHQAIVMEA
                     NASSPTGAPKLKSVIIKNVPDPATRRLLIQQGDADMARDLGADQIDALQGKPGVKVMS
                     IASAEQNYLAFNTGNKDNPLMSNPAFWEAARWLVDYDGITKNLLKGQYFTHQSFLPVG
                     FPGALEETPFTFNPAKAKEILAKAGIKDPHFTLDVENKPPFITIAQSIQASFAQGGVK
                     VDLLPAAGSQVYSRVRAHQHQGAIRMWLPDYFDAHSNASSFAYNDGKSSTVAGLNGWK
                     IPELNKETLAAIAEPDSTKRLDLYKKMQQELQRSSPYVFIDQGKTQIVMRDNVQGYQQ
                     GLNADMVWFDQVTK"
     gene            9363..10412
                     /locus_tag="ROH59_002200"
     CDS             9363..10412
                     /locus_tag="ROH59_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804680.1"
                     /translation="MSVVFSTRARWRGKRPLLALLQGLFTVALTLLGLLLITFALSAL
                     SPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLAVQFWHYLMNLAHGDLGIASSTGQPV
                     LQDLLSAFPATIELATLALIVGAVVGVIAGVLCARYVGSPLDFTVRTLTLLGNSVPVF
                     WLGLLMLALFYARLQWSAGPGRLDDIYQFTIEPRSGFALIDTWLSGDREAFTNAINHL
                     ILPVLLLAYFSLASITRLTRSACLGEMNKEYILLARAKGASEMTILLRHVLPNIRGTL
                     LTVIALAYTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVCFVLIN
                     NLTDLLVRLTDPRLR"
     gene            10412..11245
                     /locus_tag="ROH59_002201"
     CDS             10412..11245
                     /locus_tag="ROH59_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804681.1"
                     /translation="MPMFLFLRRLRHSPAAFCGLIIILLLMLIALFAPWLAPHDPNWQ
                     DAAARLQAPSRQHWLGTDSYGRDLLSRLIYGSRPALGLVALVTIITLPVGLLIGILAG
                     YYGGWLERVLMRFTDIVMSMPRLILAFAFVAMLGPGLVNGALALALTTWPAYARQARS
                     EIQRLRHSDYLAAAEMMGIRGRRLLAGHILPLCLPSAIVRLALDLAGIILAAAGLGFL
                     GLGARPPMAEWGAMIADGMQVIFDQWWIAAAPGAIILIASLAFNLLGDGLRDVLEPQH
                     D"
     gene            11238..12074
                     /locus_tag="ROH59_002202"
     CDS             11238..12074
                     /locus_tag="ROH59_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4804682.1"
                     /translation="MTDSRLSINNLCVDYPESRVVNNVSFTLGNERLALVGESGSGKS
                     MTARALMGLVRKPGVVTADTLNILGRDALTLNARGWQQLRGNDIAMVLQDPRYALNPV
                     KTVKAQLEEALTLHQRLNRREKEEKINTAIQAVGLNTRVLQSYPRELSGGMGQRVMIA
                     IALINDPRVLIADEPTSALDVRLRNQILELLVTQCEQRQMAMLLISHDLPLVAQFCHR
                     VLVMYQGNKVDEMHAAALPTATHPYTRTLWTCRPNAQTYGQMLPTLDRTAMTPEKYHD
                     DC"
     gene            12061..12765
                     /locus_tag="ROH59_002203"
     CDS             12061..12765
                     /locus_tag="ROH59_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4804683.1"
                     /translation="MTIVEINHLQVTFAEKTAVSAASFSVNAGETFSLIGESGCGKST
                     ILRVIAGLQRDWHGQVSLFGHTIKPGMRFQGDLRRNVQMVFQDPYASLHPNHTLWRTL
                     AEPLKIRGEREIEKRVQTALEQVGLPFDAARRYPHQLSGGQRQRVVIARALLLRPQLL
                     LLDEPTSALDMSVQAEILNLLNQLKLEHQMTYLLVSHDADVIAHMSDRAALMSEGKIQ
                     RFFDRDAMEKGEHRMD"
     gene            12876..13565
                     /locus_tag="ROH59_002204"
     CDS             12876..13565
                     /locus_tag="ROH59_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDX4804684.1"
                     /translation="MKKIITLMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(14054..15367)
                     /gene="gltP"
                     /locus_tag="ROH59_002205"
     CDS             complement(14054..15367)
                     /gene="gltP"
                     /locus_tag="ROH59_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HDX4804685.1"
                     /translation="MKNIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREMLGKFDKTADQ"
     gene            complement(15710..16306)
                     /gene="nrfG"
                     /locus_tag="ROH59_002206"
     CDS             complement(15710..16306)
                     /gene="nrfG"
                     /locus_tag="ROH59_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HDX4804686.1"
                     /translation="MKQPQIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRD
                     PLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     RGENAELYAALATVLYYQASQHMTVQARAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD"
     gene            complement(16303..16686)
                     /gene="nrfF"
                     /locus_tag="ROH59_002207"
     CDS             complement(16303..16686)
                     /gene="nrfF"
                     /locus_tag="ROH59_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HDX4804687.1"
                     /translation="MNKGLLTLLLLFTCFARAQVVDTWQFANPQQQEQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYTMVEEGKSEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMALILWRVRAKR"
     gene            complement(16679..18397)
                     /locus_tag="ROH59_002208"
     CDS             complement(16679..18397)
                     /locus_tag="ROH59_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HDX4804688.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLIPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGTCARICWRWALPGW
                     SALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQRGIFRH
                     WSLLLTIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFGLFVLISLASLALYGW
                     RARDGGPAVRFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFALLMLVVIVLATFVSGKRARLPTLLAHAGVLLFAAGIVVSSVSRQEISLN
                     LQPGQQVTLAGYTFRFERLDLQAKGNYTSEKAIVALFDHQQRIGELTPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGADRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GRKRDE"
     gene            complement(18417..19373)
                     /gene="nrfD"
                     /locus_tag="ROH59_002209"
     CDS             complement(18417..19373)
                     /gene="nrfD"
                     /locus_tag="ROH59_002209"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HDX4804689.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAIRQRSNPHSTEAHFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            complement(19370..20041)
                     /gene="nrfC"
                     /locus_tag="ROH59_002210"
     CDS             complement(19370..20041)
                     /gene="nrfC"
                     /locus_tag="ROH59_002210"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HDX4804690.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACRKVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTHL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            complement(20038..20604)
                     /gene="nrfB"
                     /locus_tag="ROH59_002211"
     CDS             complement(20038..20604)
                     /gene="nrfB"
                     /locus_tag="ROH59_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HDX4804691.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASGDRYEVTQQRN
                     PDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            complement(20649..22085)
                     /gene="nrfA"
                     /locus_tag="ROH59_002212"
     CDS             complement(20649..22085)
                     /gene="nrfA"
                     /locus_tag="ROH59_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HDX4804692.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPATPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            22477..24435
                     /gene="acs"
                     /locus_tag="ROH59_002213"
     CDS             22477..24435
                     /gene="acs"
                     /locus_tag="ROH59_002213"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HDX4804693.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSIDAPDTFWGEQGK
                     ILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSSSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGNPLKGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            24645..24959
                     /locus_tag="ROH59_002214"
     CDS             24645..24959
                     /locus_tag="ROH59_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HDX4804694.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPVGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            24956..26605
                     /gene="actP"
                     /locus_tag="ROH59_002215"
     CDS             24956..26605
                     /gene="actP"
                     /locus_tag="ROH59_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HDX4804695.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMLGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(26644..27333)
                     /locus_tag="ROH59_002216"
     CDS             complement(26644..27333)
                     /locus_tag="ROH59_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDX4804696.1"
                     /translation="MANFQLSMLCLAITLVIYFLNKRLYRRFRKLPLMPLVLTPTLLV
                     MLLVFGNISWQNYIGEAHWLLWLLGPATIAFAVPVYDNRAIIKRHWMSLTAGVLTATV
                     VAVTSSVWLARLFTLPDEIQRSLAVRSVTTPFALAASQSLGGQPDLVALFVVVTGVFG
                     MAIGDVLFLRLSIREGMAKGAGFGAASHGAGTARSYELGQQEGVVASLVMMLSGVLMV
                     LVSPLVARMMF"
     gene            complement(27326..27736)
                     /locus_tag="ROH59_002217"
     CDS             complement(27326..27736)
                     /locus_tag="ROH59_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDX4804697.1"
                     /translation="MPVALRRITPAVVQSIQVFFQVVLYAGLFIFAQYLVSWLHLPLP
                     ANLVGMILMLALIVCRILPLQWVRAGARWLLAEMLLFFVPAVVAVVNYAQLLLVDGWR
                     IFAVIALSTVMVLGTTAWVVEKVYRYEMRRLNRG"
     gene            27840..28724
                     /locus_tag="ROH59_002218"
     CDS             27840..28724
                     /locus_tag="ROH59_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4804698.1"
                     /translation="MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELN
                     CILLIRDGRRLLLTDTGRVVFERGLALLAEFRQLEAELSDINQLKTGVLRLGIPPMVG
                     MLMAGPIGLFRQRYPGVELKISEFGGLTVQQAVMNGELDMALTALPVEESGLTTLSLF
                     SHPLCVLTPHSGKWLECDAVSPETLAEHPLLIYNEDFALSKQLMKLFDEHGVKPRIAV
                     RSGQWDFLAAMVQAGVGIAILPEPICQRLDKNTLKWLPLESELSWKLGMIWREGVYLS
                     HSAHAWLSCCEGYWLTPE"
     gene            complement(28760..30409)
                     /locus_tag="ROH59_002219"
     CDS             complement(28760..30409)
                     /locus_tag="ROH59_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HDX4804699.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSILEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(30560..31909)
                     /gene="ghxP"
                     /locus_tag="ROH59_002220"
                     /gene_synonym="yjcD"
     CDS             complement(30560..31909)
                     /gene="ghxP"
                     /locus_tag="ROH59_002220"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HDX4804700.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFTTFPVMMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(32456..32920)
                     /gene="soxR"
                     /locus_tag="ROH59_002221"
     CDS             complement(32456..32920)
                     /gene="soxR"
                     /locus_tag="ROH59_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HDX4804701.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIREAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            33006..33329
                     /gene="soxS"
                     /locus_tag="ROH59_002222"
     CDS             33006..33329
                     /gene="soxS"
                     /locus_tag="ROH59_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HDX4804702.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(33332..34918)
                     /gene="pdeC"
                     /locus_tag="ROH59_002223"
     CDS             complement(33332..34918)
                     /gene="pdeC"
                     /locus_tag="ROH59_002223"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HDX4804703.1"
                     /translation="MSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIRLNDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLFLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAEFIPLAEKEGMIEQV
                     TDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKF
                     EVTEHAFLDVDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEAQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            35347..35628
                     /locus_tag="ROH59_002224"
     CDS             35347..35628
                     /locus_tag="ROH59_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HDX4804704.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRADYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(35727..36263)
                     /gene="ssb1"
                     /locus_tag="ROH59_002225"
     CDS             complement(35727..36263)
                     /gene="ssb1"
                     /locus_tag="ROH59_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HDX4804705.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            36518..39340
                     /gene="uvrA"
                     /locus_tag="ROH59_002226"
     CDS             36518..39340
                     /gene="uvrA"
                     /locus_tag="ROH59_002226"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDX4804706.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPDGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(39375..39731)
                     /locus_tag="ROH59_002227"
     CDS             complement(39375..39731)
                     /locus_tag="ROH59_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDX4804707.1"
                     /translation="MTILELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(39735..40151)
                     /locus_tag="ROH59_002228"
     CDS             complement(39735..40151)
                     /locus_tag="ROH59_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HDX4804708.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRAVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(40262..40975)
                     /gene="aphA"
                     /locus_tag="ROH59_002229"
     CDS             complement(40262..40975)
                     /gene="aphA"
                     /locus_tag="ROH59_002229"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HDX4804709.1"
                     /translation="MRKITQALSAVCLLFALNSSAVALASSPSPLNPGTNVAKLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
     gene            41252..43072
                     /locus_tag="ROH59_002230"
     CDS             41252..43072
                     /locus_tag="ROH59_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDX4804710.1"
                     /translation="MKISWNYIFKNKWRFHITSISLFLIMLAVSIAFLHLRFNTLSGT
                     DKMRLEMYKSTLYSTIEQFYVLPYMLSTDHIIRQAVITPDDMTSSELNQRIAHFNTQL
                     KTAAIFILDTQGKAIASSNWQDPGSYVGQNYSYRPYYKHAMSGLNGRFYGIGSTTNTP
                     GFFLSTSIKDKGKIVGVVVVKISLNEIEKAWAEGPENIIVNDEHGIIFLSSKSPWRMR
                     TLQPLPVQAKQKLQSTRQYSLDNLLPADYYPCYTVSNFTFLKDKKEQLCLFPQYYTQQ
                     IAIPEFNWKMTIMVPLDNLYWSWAISLVITLIIYLLFLLFIKYWRMRSHAQQLLTLAN
                     ETLEKQVKERTSALELINQKLIQEIKERSQAEQVLQITRSELAESSKLAALGQMATEI
                     AHEQNQPLAAIHALTDNARTMLKKEMYPQVEQNLKHIISVIERMTQLISELKAFASRH
                     RVPKGSADVIKVMYSAVALLNHSMEKNNIERRIKAPSMPLFVNCDELGLEQIFSNLIS
                     NALDSMEGSSYKRLDIAIRQANNKVIITIKDSGGGFAPEVVDRIFEPFFTTKRRGMGL
                     GLAIVSEIVRNSNGALHASNHPEGDAVMTLTWPEWGEKHE"
     gene            43065..44423
                     /locus_tag="ROH59_002231"
     CDS             43065..44423
                     /locus_tag="ROH59_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDX4804711.1"
                     /translation="MNNKFSEITIVYIEDSDDVRFACEQTLTLAGYRVISCCDAEHSI
                     PLIQSQANIIILTDVRLPGISGLELLSYINEMDSKIPVILITGHGDVEMAVDAMRNGA
                     FDFIEKPSSSDKLLSIIARAVEKRRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKM
                     ILNVADTGADVLIYGETGCGKEVVARMLHHWSTRRQGQFVALNCAGLPETLFESEIFG
                     HEAGAFTGAVKKRIGKIEHANGGTLFLDEIEGMPSGMQVKLLRVLQERTIERLGANQL
                     IPVNCRVIAATKEDLLRRSEEHLFRLDLYYRLNVVSLNIPPLRQRREDIPELFYWFAS
                     QAAQKYNRPLPDISPMLLAWLQSQSWPGNVRELKHNAERFVLGLLTHHQPVPMTQQEE
                     SGLTACIDAFEKKLIEDMLRQTEGQVSLTARLLQLPRKTLYDKLNKHQIQPQVYRPES
                     SS"
     gene            complement(44412..45485)
                     /locus_tag="ROH59_002232"
     CDS             complement(44412..45485)
                     /locus_tag="ROH59_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ldh family oxidoreductase"
                     /protein_id="HDX4804712.1"
                     /translation="MSLQIAVEKVRWLAAGLLELNGCDADIAQDVAEHMIEAERYGFA
                     SHGVTLLPKYLENIARGDVTANARPECLTSEGNLQRFHAHNGFGQHAGKVAVNAAIEQ
                     TKHRGFCLLTLCHAHHLGRMGHYGQMVADQGLAMLAMSNVTGRPALVAPWGGAEPRMT
                     TNPFCFAWPFSDGRPPILVDFATSSMALNKARVMSSTGKQAAPGQLIDAQGNPSNDPG
                     VLFSNPPGALLPFGEHKGFGLALMIEMMAGILSGGDTIAEDHQTDGSAHNHLFALIID
                     PDQFTDLAGEKGQFFADYLLATQPQPGGNPVIYPGMPEAANRERNAKMITIPVSFWSW
                     VVEHYARKGIDLGLHPQESALAG"
     gene            complement(45497..46996)
                     /locus_tag="ROH59_002233"
     CDS             complement(45497..46996)
                     /locus_tag="ROH59_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HDX4804713.1"
                     /translation="MSSISHGAPQKRRIIPNPGLWLAIIAGIIITLLPLGDTLPVAGQ
                     NMIAILVFAIIVWISEAMDYTASAIVISALIIFMVGFAPDMNHPDTILGTAKALKMTL
                     SGFSNSALALVAAAMFIAAAMTITGLDKRIALFTMSKIGASSRSIIIGAIVVTIVLSL
                     VVPSATARTACVVPIMMGVIAAFKVDKHSRLAASMMIVIAQATSIWNVGIQTSSAQNL
                     LSIGFINKTFGAGHSVSWLDWLLAGAPWSLTMSVILYFLARKLLPPETEAVEGGSEAI
                     KKALAELGPTTGKEKRLIGISLLLLLFWSTGGKLHSIDTTSVTLAGLAIMLLPGIGVM
                     SWKEVEKRVQWGTLLMFGIGISLGSTLLDTQAASWMANYVVKGFGLDGLPSLAIFAIL
                     AAFLIIIHLGFASATALTAALLPILISLLSSLPPELGVNPVGMTILLAFSVSFGFILP
                     INAPQNMVCMGTDTFTPRQFTRVGLYLTVIGYLLLLLFAATWWKILGLM"
BASE COUNT        11793 a        12472 c        11924 g        10893 t
ORIGIN      
        1 taatatatat aagttatgaa tgcggtggct gaataaagct atttttattc atcgagaaaa
       61 tagccatact gacgccttca atggatattg atattcacta cagatattgt tcgcagcaga
      121 caggatgtat ttaatatgcc aacagttctc tctcgcatag cgatgcaact caaaaaaata
      181 gcctggataa ttcccgtctt catggtttcg ggatgctcat tatctccggc aatcccggtg
      241 atcggcgctt attatcccgg ctggtttttc tgcgccattg ccagccttat tttgacgctc
      301 atcacgaggc gaattattca gcggacaaat atcaatctgg catttgtcgg aattatttat
      361 accgcccttt ttgctctcta cgccatgctg ttctggctgg catttttcta atcaatttga
      421 gacgcgctca tggaaagtac gccgaaaaaa gctcctcgca gtaaattccc tgctctgtta
      481 gtggttgcgt tggcgctggt tgcccttgtt ttcgttatct ggcgcgtaga cagtgcgcca
      541 tcaactaatg acgcttacgc gtcagcagat accattgatg tggtgccgga agtcagcggt
      601 cgcattgtag aactggcggt cagcgacaac caggcggtga aacagggcga tttgctgttc
      661 cgcattgacc cgcgcccgta cgaagccaat ctggcgaaag ctgaagcctc cctcgcggcg
      721 ctggataagc aaattatgct cacccagcgt agcgttgacg cgcaacagtt tggtgccgac
      781 tcggttaatg ccacggtaga aaaagcccgt gccgccgcga aacaagccag cgatacgtta
      841 cgccgtaccg aaccgctact gcgagaaggt tttgtttctg cggaagaggt tgaccgtgca
      901 agaaccgccc agcgtgcggc agaagcggac cttaatgccg tattgttgca ggcgcagtca
      961 gccgccagtg ccgtcagcgg cgtcgatgcg ctggtcgccc aacgtgcggc ggtcgaagcg
     1021 gatattgccc tgaccaaact gcatctggaa atggcgaccg ttcgcgcgcc gtttgatggc
     1081 cgggtcattt ccctcaaaac ctccgtcggg caatttgctt ctgccatgcg ccctattttc
     1141 accctaatcg acactcgtca ctggtacgtg atcgccaatt tccgcgaaac tgatctgaaa
     1201 aatattcgct caggtacacc cgcaacgatt cgcctgatga gcgacagcgg caaaaccttc
     1261 gagggtaaag tggattcgat tggctacggc gtgctaccgg atgacggcgg cctggtgctg
     1321 ggcggcctgc cgaaagtgtc gcgttctatt aactgggtcc gcgttgccca gcgttttccg
     1381 gtcaaaatca tggttgataa acctgacccg gaaatgttcc gcatcggcgc ttcggcagtc
     1441 gctaatcttg agccgcaata atgagcgcgc tcaactccct gccattaccg gtggtcaggc
     1501 tgctggcgtt ctttcatgaa gagttaagcg agcggcggcc aggtcgtgtg ccgcagaccg
     1561 tgcaactctg ggtaggctgc ctactggtga ttctgatctc gatgactttt gagatccctt
     1621 ttgtggcgtt atcgctggca gtgctgtttt acggtattca gtcgaacgcg ttttacacca
     1681 aatttgtggc gatcttgttt gtggttgcca cggtgctgga gatcggcagc ctgtttttga
     1741 tctacaaatg gtcatacggc gaaccgttga tccgattgat catcgccggg ccgatcctga
     1801 tgggctgcat gtttttgatg cgcacccatc ggctggggct ggtctttttc gccgtcgcca
     1861 ttgtcgctat ttacgggcaa accttccccg ccatgctcga ctatccggaa gtggtcgtgc
     1921 gcttaaccct gtggtgtatc gttgtcggcc tctacccgac gttattgatg acgttaatcg
     1981 gcgtgctgtg gtttcccagc cgcgctatca cgcagatgca tcaggcgctt aatgatcggc
     2041 ttgatgatgc cattagccac ctgacggaca gcctcgcacc gctacccgaa acgcggattg
     2101 aaagagaggc gctggcgctg caaaaactca atgtcttttg cctcgcggac gatgccaact
     2161 ggcgaactca gagcgcatgg tggcaaagct gcgtggcaac ggtaacctac atttactcga
     2221 cgctgaatcg ctacgatccc acctcttttg ctgattctca ggcaattatt gaattccgac
     2281 aaaaattagc ctcagaaatc aacaaactgc agcatgccat tgccgaaggt cagtgctggc
     2341 aaagcgactg gcggatcact gaaagtgaag cgatggcggc acgggaatgt aacctggaga
     2401 atatctgcca gacattgttg caactgggtc agatggaccc gaatacgccg ccaacgcccg
     2461 ccaccaaacc gccatcaata gtcgccgacg cttttaccaa tccagactat atgcgctacg
     2521 cggtaaaaac gctgctcgcc tgtttgatct gttacacctt ctacagcggc gtggactggg
     2581 aaggcattca cacctgtatg ctgacctgcg tgatcgtcgc taatccaaat gtcggttcgt
     2641 cgtaccagaa gatggtgctg cgttttggcg gggccttttg cggcgcgatt ctggcgctgt
     2701 tattcacgct actggtcatg ccctggctgg acaatattgt cgaattgctg tttgtgctgg
     2761 caccgatttt cctgttgggc gcatggattg ccaccagctc tgaacgctct tcttatatcg
     2821 gcacacagat ggtggtcacc ttcgcgctcg ccacgctcga aaacgttttt ggcccggtgt
     2881 acgacctggt ggaaattcgc gatcgcgctc tgggtatcat cattggtacc gtggtgtcgg
     2941 cggtgattta cacctttgtc tggcctgaaa gcgaagcgcg cacgctgccg caaaaactgg
     3001 ctggcgcgct gggtatgttg agtaaagtaa tgcggatccc acgccagcag gaagtcacgg
     3061 ctctgcgcac ttatctgcaa attcgcatag gtctgcatgc ggcgtttaat gcctgtgaag
     3121 agatgtgcca acgcgtggtg ctggagcgtc aactggacag cgaagaacgc gccttactga
     3181 ttgaacgttc gcaaacggtt attcgtcagg gccgcgatat tcttcacgcc tgggatgcca
     3241 cctggaactc ggcgcaggcg ctggataacg cactacagcc ggacagagca ggtcagtttg
     3301 ccgacgcact ggagaaatac gccgctggtc tggcaaccgc actcagccgt tctcctcaaa
     3361 taacgcttga agaaacaccc gcctcgcagg ccatcctgcc caccttatta aaacaggagc
     3421 aacacgtctg ccagcttttc gcccgcttgc cagactggac agccccggca ttaacgcccg
     3481 ccaaggaaca ggcacaagga gccacacaat gatcaatcgt caactttcac gtctgctgtt
     3541 gtgcagcatt ctcggcagca cgacgctgat ttccggctgt gccctggtac gtaaggattc
     3601 tgcgcctcat caacagctca aaccggaaca aatcaaactg gccgatgata ttcatcttgc
     3661 cagctccggc tggccgcagg cgcagtggtg gaaacaactc aatgacccgc agctggatgc
     3721 gctgatccaa cggactctaa atggttcaca caccctcgcc gaagcgaaac tgcgggaaga
     3781 aaaagcgcag tcccaggccg atttgttaga tgccggttca caattacagg tcgcagcgtt
     3841 agggatgctc aaccgccaac gcgtctcggc gaacggcttt ttaagccctt atgcgatgga
     3901 tgcgccagca ctgggtatgg acgggccgta ctatacggaa gccacagtcg gtttgtttgc
     3961 cggactggat ctcgatttgt ggggtgtgca tcgctcagcg gttgctgccg ccattagcgc
     4021 gcataatgcc gcgctggcag aaaccgcagc agtagagcta tcgctgacca cgggcgtagc
     4081 gcagctttat tacagtatgc aggccagcta tcagatgctc gatctgttag aacaaactcg
     4141 cgatgtgatt gattacgcgg tgaaagcgca ccagagtaaa gtggcgcacg gtctggaagc
     4201 gcaagtgcct ttccacggcg cgcgggcaca gattctggcg gtcgataaac aaattgctgc
     4261 cgtcaaaggg caaatcaccg aaacgcgaga atctctgcgt gcattgattg gcgcgggagc
     4321 cagcgatatg ccggagatca aaccggtggc attaccgcaa gtccagaccg gtattccggc
     4381 gacactctct tatgagttgc tcgccagacg cccggatctg caagccatgc gctggtatgt
     4441 tcaggcgtca ttagatcagg tggattccgc gcgggcgctg ttctatccga gctttgatat
     4501 caaagcgttt ttcggcctgg attctatcca cctggatacc ttattcaaaa aaaccagtcg
     4561 ccagttcaac tttatcccag gtctgaaatt gccgctgttt gacggtggac ggttgaatgc
     4621 caatctcgaa ggcactcgcg ccgccagcaa catgatgatt gaacgttaca accagtcagt
     4681 actgaacgcg gtgcgtgacg ttgccgtcaa cggcacacgt ctgcaaacgc tcaacgacga
     4741 gcgagagatg caggctgaac gcgtagaagc aacgcgcttc acccagcgcg cagccgaggc
     4801 cgcctaccaa cgcggcttaa ccagccgctt acaggccacc gaagcccggt tgccagtgct
     4861 tgccgaagag atgtcattac tgatgctgga cagccgccgg gtgatccaaa gcattcagtt
     4921 gatgaaatcg ctgggcggcg ggtatcaggc ggctcccgtc gtcgagaaaa aataaaatgt
     4981 ctaccgcgtg atggctgtca cgcggtattt cgtttcgtca cgtcaaaact gacgacagcc
     5041 tgtttttcgt cagagttttg aataaatagt gcccgtaata tcagggaatg accccaaata
     5101 aaatgtggca taaaagatgc atactgtagt cgagagcgcg tatgcgtgat ttgattaact
     5161 ggagcgagac cgatgaaaaa agtcgtcacg gtttgcccct attgcgcatc aggttgcaaa
     5221 atcaacctgg tcgtcgataa cggcaaaatc gtccgggcgg aggcagcgca ggggaaaacc
     5281 aaccagggta ccctgtgtct gaagggttat tatggctggg acttcattaa cgatacccag
     5341 atcctgaccc cgcgcctgaa aacccccatg atccgtcgcc agcgtggcgg caaactcgaa
     5401 cctgtttcct gggatgaggc actgaattac gttgccgagc gcctgagcgc catcaaagag
     5461 aagtacggtc cggatgccat ccagacgacc ggctcctcgc gcggtacggg taacgaaacc
     5521 aactatgtaa tgcaaaaatt tgcgcgcgcc gttattggta ccaataacgt tgactgctgc
     5581 gctcgtgtct gacacggccc atcggttgca ggtctgcacc aatcggtcgg taatggcgca
     5641 atgagcaatg ctattaacga aattgataat accgatttag tgttcgtttt cgggtataac
     5701 ccggcggatt cccacccaat cgtggcgaat cacgtaatta acgctaaacg taacggggcg
     5761 aaaattatcg tctgcgatcc gcgcaaaatt gaaaccgcgc gcattgctga catgcacatt
     5821 gcactgaaaa acggctcgaa catcgcgctg ttgaatgcga tgggccatgt cattattgaa
     5881 gaaaatctgt acgacaaagc gttcgtcgct tcccgtacag aaggctttga agagtatcgt
     5941 aaaatcgttg aaggctacac gccggagtcg gttgaagata tcaccggcgt cagcgccagt
     6001 gagattcgtc aggcggcgcg gatgtatgcc caggcagaaa gcgccgccat cctgtggggc
     6061 atgggggtaa cccagttcta tcagggcgtg gaaaccgtgc gttctctgac cagcctcgcg
     6121 atgctgaccg gtaacctcgg taagccacat gcgggtgtaa acccggttcg tggtcagaac
     6181 aacgtgcagg gtgcctgcga tatgggcgcg ctgccggata cgtatccggg ctatcagtac
     6241 gtgaaagatc cggctaaccg cgagaaattt gccaaagcct ggggcgtaga gagcctgcca
     6301 gcgcataccg gttatcgtat cagcgagctg ccgcaccgcg tggcgcatgg tgaagtgaga
     6361 gcggcgtaca ttatgggcga agatccgctg caaactgacg cggaactgtc ggcagtacgt
     6421 aaagcctttg aagatctgga actggttatc gttcaggaca tctttatgac caaaaccgcg
     6481 tcggcggcgg atgtcatttt accgtcaacg tcgtggggcg agcatgaagg cgtgtttact
     6541 gcggctgacc gtggcttcca gcgtttcttc aaggcggttg agccgaagtg ggatctgaaa
     6601 acggactggc aaatcatcag tgaaattgcc actcgtatgg gttatccgat gcactacaac
     6661 aacacccagg agatctggga tgagttgcgt catctgtgcc cggatttcta cggtgcgact
     6721 tacgagaaaa tgggcgaact gggcttcatt cagtggcctt gccgcgatac ttcagatgcc
     6781 gatcagggga cttcttatct gtttaaagag aagtttgata ccccgaacgg tctggcgcag
     6841 ttcttcacct gcgactgggt agcgccaatc gacaaactca ccgacgaata cccgatggta
     6901 ctgtcaacgg tgcgtgaagt tggtcactac tcttgccgtt cgatgaccgg taactgtgcg
     6961 gcactggcgg cgctggctga tgaacctggc tacgcacaaa tcaataccga agacgccaaa
     7021 cgtctgggta ttgaagatga ggcattggtt tgggtgcact cgcgtaaagg caaaattatc
     7081 acccgtgcgc aggtcagcga tcgtccgaac aaaggggcga tttacatgac ctaccagtgg
     7141 tggattggtg cctgtaacga gctggtgacc gaaaacttaa gcccgattac gaaaacgccg
     7201 gaatacaaat actgcgccgt gcgcgtcgag ccgatcgccg atcagcgcgc cgccgagcag
     7261 tacgtgattg acgagtacaa caagttgaaa actcgcctgc gcgaagcggc actggcgtaa
     7321 taccgcttaa actcacgtta aaagcggtga tattacccaa cgcctttgta tcaatccgga
     7381 aacgactctc tgtttccgga tttttttata catacctgcg cagtcaaacc agcctatcct
     7441 ggttattagc gacgtcttct cggttgttct tctattccag tcacgattgc aaatgagaat
     7501 tatctttact caattctcat cgcggcctaa cgtaataata ctttacattt gatgaaccaa
     7561 atttcggtaa ggtgagaaat catcgaccgt ttaactcgtt ctattaacgg gatattttgg
     7621 cgcgattaat gcaacaaaac cccgtctgat agaatattaa taacctcaaa gtaatttcag
     7681 ggattgggaa gcatatgatt aaaaaactat tacctttact ggttttaagc acaatttccg
     7741 ccacaaccgt tgccgctaca ccgcctaata cgttggttgt agcccagggg ctggatgata
     7801 ttgtgagcct ggacccggca gaagctaatg aactctcaag tattcagact gtaccaagtc
     7861 tgtatcaacg cgtagtgcaa ccggaccgta atgatccgac gaaaattact ccgattctgg
     7921 cggaaagttg gcaggctgac cccgcagcca aaacgctaac cataaaactg aaaagcgatg
     7981 cgaaatttgc ctctggtaat ccggtacgcc cggaagatgt gatttactct tatgtccggg
     8041 ctgtcacact gaataaatcc ggtgcgttta ttctcaatgt gctgggatgg cagccggaaa
     8101 atatcgccag ccagttgaag aaaatcgatg accataccgt ccaggtgcaa tggagtgccg
     8161 acgtcagccc ggctctggca ctgaatattc tctccacacc aatcgcctca attgttgacg
     8221 agaagctggt tgcgccaaac gccaaaaata acgactttgg taatgaatgg ctgaagatgc
     8281 attccgctgg cagcggcgcg tttaaaatgc gtacttacca accgcatcag gccatcgtga
     8341 tggaagccaa cgccagctca ccaaccggcg ccccgaaact gaaaagcgtc atcatcaaaa
     8401 atgttcccga tccggcaaca cgtcgcctgc tgatccaaca aggtgatgct gatatggctc
     8461 gtgatctggg agccgatcaa atcgatgcat tacagggtaa acctggcgta aaagtgatga
     8521 gcattgcctc cgccgaacag aactacctgg ccttcaatac cggtaacaag gataacccgc
     8581 tgatgagtaa tcctgcgttc tgggaggccg ctcgctggtt ggtcgattac gacggcatca
     8641 ccaaaaatct cttaaaagga caatatttta cccatcagag tttcctgccc gtgggctttc
     8701 ctggagcact ggaagaaaca ccgtttacct ttaatccagc caaagcaaaa gagatcctcg
     8761 ctaaagccgg aatcaaagac ccgcacttca cgcttgatgt cgaaaataaa ccgccattta
     8821 ttaccatcgc gcagtcaatt caggccagct ttgctcaggg cggtgtaaaa gttgatttgc
     8881 tgccagccgc agggagtcag gtctactctc gcgttcgcgc ccaccagcat cagggggcca
     8941 ttcgtatgtg gttgcctgat tattttgacg cacattccaa cgccagctct ttcgcctata
     9001 acgatggcaa atccagcacc gttgccgggt taaacggctg gaaaatcccg gaactgaaca
     9061 aagaaacgct ggcggccatc gctgaacctg atagcactaa acgtcttgat ttgtataaga
     9121 aaatgcaaca agaactacaa cgtagttccc cgtatgtctt tattgatcaa ggcaaaacgc
     9181 aaattgtcat gcgtgataat gtgcaggggt atcaacaagg gttgaatgcc gatatggtct
     9241 ggtttgatca ggtaaccaaa taaccctgta tgcaactcgc gtccagccat gttaccgggc
     9301 gcggtaccag ggctggcctg tattgcaggc cagccgctga tttatcactg tatggaaaga
     9361 tcatgtctgt cgttttttcc actcgcgcaa gatggcgagg caaacgccct ctgctcgcgc
     9421 tgttgcaagg gctgtttacc gttgctctga cgctactcgg cctgctgctg attacctttg
     9481 cgctttcggc tctctcaccg gtcgatcgcg tactacaaat cgttggcgat cacgccagcc
     9541 agtccaccta tgatcaggta cgccaccagt taggattgga tcagccgtta gccgtccagt
     9601 tctggcatta cctgatgaat ctggcacacg gcgatctggg catcgccagc tccaccgggc
     9661 aaccagtact ccaggacttg ctatcagcat tcccggcgac cattgaactg gcaacgttgg
     9721 cgcttattgt cggtgctgtt gtcggcgtca ttgcgggtgt actttgcgcc cgttatgtcg
     9781 gttctccgct ggatttcacc gtgcgaacat taactctact gggaaattcc gtccctgttt
     9841 tttggcttgg tctgctgatg ctggcgctgt tctacgccag actgcaatgg agtgccgggc
     9901 cgggcaggct ggatgatatt tatcaattca ccatagaacc ccgcagcgga tttgcgctga
     9961 ttgatacgtg gctttctggc gatcgcgagg catttaccaa tgcaatcaac catttgatac
    10021 ttccggtttt attactggcg tacttctcgc tcgccagtat tacgcgcctg actcgttccg
    10081 cctgtcttgg cgaaatgaat aaagaatata ttctgctggc gcgcgccaaa ggggccagcg
    10141 agatgacaat tttgctacgt catgttttac ccaacattcg cggcaccttg ctcaccgtta
    10201 tcgccctcgc ctatacatca atgctggaag gcgcggtact gacagaaacc gtcttttcat
    10261 ggccaggtat tgggcgctac ctcactacag cgctcttcgc gggtgatacc acagcaatca
    10321 tgggaggaac gctgctgatt ggcgtctgct ttgtgttgat aaataactta accgacctgc
    10381 tggtccggct gaccgatccg aggttacgct gatgccgatg tttctctttt tacgccgttt
    10441 acgccattca cccgccgcgt tttgcgggtt gataattatc ctgttattga tgctaattgc
    10501 gctcttcgcg ccgtggctgg cacctcacga tcctaactgg caggatgcgg cggcgcgatt
    10561 acaagcaccg agtcgtcagc actggctcgg cactgacagt tacgggcgag acctactttc
    10621 acgtttaatc tacggcagcc gcccggcact ggggctggtg gcattggtga caatcattac
    10681 actcccggtc ggtctgctga ttggcatttt agccgggtac tacggcggct ggctggaacg
    10741 cgtgctgatg cgttttactg acatagtaat gtcaatgccg cgtttaattc tggcttttgc
    10801 ttttgttgcc atgctggggc cggggctggt taacggcgca ctggcccttg cattaaccac
    10861 ctggcctgct tatgcgcgtc aggcacggag tgagatccaa cgtctgcgac acagtgatta
    10921 tcttgccgcc gcagaaatga tgggcatccg cggcaggcgt ctgctggctg gtcatatttt
    10981 gccattgtgc ctgccatctg ccattgtccg tctggcgctg gatttagcgg gtatcattct
    11041 ggcggctgct ggtctgggtt ttcttgggct tggtgctcgc ccgccaatgg cggaatgggg
    11101 agccatgatc gccgacggta tgcaggtcat ttttgatcaa tggtggattg ccgccgctcc
    11161 cggcgcaatt atcttaattg ccagtctggc ctttaatctg ctgggtgatg gcttgcgcga
    11221 tgttctggag cctcaacatg actgactcac gtcttagtat caacaatctc tgcgtcgatt
    11281 atccggagtc ccgggtcgtc aacaatgtca gttttacatt aggcaatgaa cgtctggcgc
    11341 tggtcggtga gtcgggttca ggtaagtcca tgaccgcccg cgccctgatg gggctggtgc
    11401 gtaaaccggg tgtagtaacc gcggacacac ttaacattct ggggcgtgat gcactcaccc
    11461 ttaacgcgcg tggatggcaa cagttgcgcg gtaacgatat cgcgatggta ttgcaagatc
    11521 cgcgttacgc gcttaatcca gtaaagacag taaaagcgca actggaagag gcgcttacgc
    11581 tccatcaacg tctgaaccgc cgcgagaaag aagagaaaat aaacaccgca attcaggctg
    11641 tcggcctcaa tacgcgagta ctgcaaagct atcctcgtga actttctggc ggcatggggc
    11701 agcgagtgat gattgcaatt gcgctcatca acgatccccg ggtattgatt gccgatgagc
    11761 caacatcagc actagatgtg cgcctgcgta atcagattct ggaactgctg gttacccagt
    11821 gtgaacaacg tcagatggca atgttgctga tcagtcacga cctgccatta gttgcccaat
    11881 tttgccatcg ggtgctggtg atgtatcagg gaaataaggt ggatgaaatg cacgctgctg
    11941 cgctacctac agcaacgcat ccttacacgc gcacactgtg gacttgccgc ccaaatgcac
    12001 aaacttacgg gcagatgctg ccgacgctgg acaggacggc aatgacgccg gagaaatacc
    12061 atgacgattg ttgaaattaa tcacttacag gtgacttttg ctgagaaaac cgcagtttct
    12121 gccgccagtt tttcggttaa tgccggagag acatttagtt taattggcga atcaggctgc
    12181 ggaaaatcca cgattttgcg cgtaattgct ggattacagc gcgactggca cggtcaggtg
    12241 tcactgtttg ggcacaccat caaaccagga atgcgttttc agggcgatct ccgccgcaat
    12301 gtgcaaatgg tgtttcagga tccctatgcc tcgttgcatc ccaatcatac tctgtggcga
    12361 acgctggctg aaccactcaa aattcgtggc gaaagagaaa tagaaaaacg cgtccagact
    12421 gcactggaac aggttggctt gcctttcgac gccgctcgtc gctacccaca ccagctttcc
    12481 ggtggtcaac ggcaacgtgt ggttattgct cgcgccctgt tgttacgacc acaacttctt
    12541 ctgctggatg aacccacctc ggcgttggat atgtcggtac aagcggaaat ccttaatttg
    12601 ttgaatcaac ttaagctgga acaccaaatg acatatctgc tggtcagtca cgatgccgat
    12661 gtcatcgcgc atatgtctga tcgagcggca ttgatgtccg agggaaaaat tcagcgattt
    12721 tttgatcgcg acgccatgga aaagggggaa catcggatgg attaaaaaac ctgacattgc
    12781 attaattcat tctgctttca ggtcttttta cagttgtttt tttgtccacc cgaacacttt
    12841 atactgtctc tcccctacca aacttcatta tcaaaatgaa aaaaattatc actttgatgt
    12901 tgtttttgac attctttgcc cacgcgaacg actccgagcc tggcagccag tatttaaagg
    12961 cagcagaggc cggagaccga cgcgcacaat attttcttgc cgacagctgg tttagctccg
    13021 gcgatttgag caaagccgaa tattgggcac agaaagccgc cgacagcggt gatgccgatg
    13081 cctgcgcgct gttggcgcag atcaaaatca ccaatccggt cagtctggac tatccacaag
    13141 caaaagtgct tgccgagaaa gcagcgcaag cgggcagtaa agaaggtgaa gtaacgctgg
    13201 cgcatattct ggtaaatacg caagcgggta aaccggatta tccaaaggcg atttcgctgt
    13261 tagaaaacgc ctcggaagat ctggagaacg actctgccgt cgatgcccaa atgctgcttg
    13321 gtttgattta cgccaacggc gtgggcatta aggccgacga tgacaaagca acctggtatt
    13381 tcaaacgtag ctctgcgatt tcccgaaccg gttattccga atactgggcg ggaatgatgt
    13441 tcttaaacgg tgaagagggt tttatcgaga agaataaaca aaaggcgctg cactggttga
    13501 atctgagctg tatggaagga tttgataccg gttgtgaaga gtttgaaaaa ttaactaacg
    13561 gttaaggtag gcgcagcaaa cgtcgcatca ggcattgatg tcggatgcgg cgtaaacgcc
    13621 ttatccgacc tacaaaaatc acgccaaatc aggctattgc gctgtctgac gtaggcctga
    13681 taagacacgt cagcatcgca tcagacattg atgccggatg cggcgtaaac gccttatccg
    13741 acctacaaaa atcacgccaa atcaggctat tgcgctgtct ggcgtaggcc tgataagacg
    13801 cggcaagcgt cgcatcaggc gttgatgtcg gatgcggcgt aaacgcctta tccgacctac
    13861 aaaaatcacg ccaaatcagg ctattgcgct gtctggcgta ggcctgataa gacgcgttaa
    13921 gcgtcgcatc aggcgttgat gtcggatgcg gcgtaaacgc cttatccgac ctacaaaaat
    13981 cacgctacat caggctatta ctcagtcagg catccacaca ttgccgggtg gatatccccc
    14041 cggcaatctt caattactga tctgctgttt tatcaaattt gcccaacatt tcacgctcgt
    14101 aggccagcgc ttttttacgg tcaaatttgt gttcccactt ggcaatcacc agcaccgcca
    14161 gcgcattacc caccacgttc agcgcagtac gcgccatatc gaggatacgg tcaacaccgg
    14221 caataaacgc cagaccttcc agcggaatac ctacgctacc cagcgttgcc agcagcacca
    14281 caaacgacac gcccggcacg ccagcaatcc ctttcgaggt caccatcagc gtcagcacca
    14341 gaatgatttc ctgccagatg gacaggtcaa tgccatacag ctgagcgatg aaaatagcgg
    14401 caatactttg atacagcgtc gaaccatcaa ggttaaaaga gtaaccggtc ggcaccacga
    14461 aactggtgat cgacgccggt gcaccgtagg cttccatctt ctcaataatt cgcggcagca
    14521 cgctttcaga actggcagta gagtacgcca gaatcagctc atctttcaga atacgaatca
    14581 ggatccagac acttaacccg cacaggcgcg ccacaattcc cagtacgacc agcgcgaaga
    14641 acagaatggc gaaatgcacc agcagcacca gtttcgccag tggccacaga gaagagaaac
    14701 caaagttagc caccgtcacc gcaatcagcg caaacacacc caccggcgca taacgcatca
    14761 ccatgtgagt cactttaaac atggtttcag agatggagcg gaaaacggtc accagcggtt
    14821 cacgatgcgt cgcgggcagg gatgaaagcc ccagaccaaa cagcaccgag aagaagatga
    14881 tcggcagcat ttcgcctttc gccatcgacg ccacgatgtt cgtcggcacc agcgacaaaa
    14941 tcgtgcccat aatgccgtgg gaactgcttt gtaccgcttc cgtagtgctc tgatatttcg
    15001 agatatcgac ggtcgccagc tgcgacatat ccaccccggc accgggctgg aagacgttcg
    15061 ccagagtgat ccccaaaatg atggcgacgg tggtgatcac ctcgaagtag ataatggttt
    15121 tcgcaccaat acgcccgagc tgtttggcat caccaacacc cgcgataccc accaccagcg
    15181 tggagatcac aatcggcaca acaatcattt tgatcagatg gatgaagata tcacccgccg
    15241 gagagagcaa attgacgacc agccagtcgc ggctgtcgct atggtagtgc aggtagcttc
    15301 ccaggagaat gcccagcacc atagcaaaca gaatctgcca ggccaggctg aattttatat
    15361 ttttcatcag aataacttcc tcaatggagc gccgttcccc gttcagaaac gcgagaacgt
    15421 gacatactgc cagggcatga attgtgttgc gttggtttgt agattttttt aacgcttatg
    15481 atcagtatca tttgcgcggt atgttgcgca accctttaac aacagagctt ttcgctgcat
    15541 taatgcataa taacgcgagt ttatggcagg attaatgaat aaccatttgt tatagaagga
    15601 tttttatttg tttaatctgc aataatactg attagtgatt atttttgatt atatgttcat
    15661 tcgattattt tttatgcagc tcaataacat aatcttcatc accagatgat taatctgatc
    15721 tccgctgcaa caatttcgcc atattaatcg actcgaccag ctgtgtccgg ttgatccggg
    15781 gtgagttgag atccatcact ttttgccata gttcgatggc ttgcgcgtaa ttcgcctgca
    15841 taaacgcatc ggaagccagc agcatcagag cggtgatttc gttagagtcc agcgcgaggg
    15901 ctttgtcgat cattgcgcga gcctggacgg tcatatgttg gctggcctgg taatacagca
    15961 ccgtcgccag cgccgcatac agttcagcgt tctcaccacg tagttgcaac gcctgacggt
    16021 acgccagcag cgaattgctg taatcgtttt gccacagata atactcgccc agtaacgccc
    16081 actgttcgct gttttgtgga ttagcacgga ttttatcctg caatgcctga agctgcgctt
    16141 ccggggtttg ctggctggca aactgatgca gcggatcgcg ctgacgctga tactccgcac
    16201 gtaccgcctg ccattttgga cttaacagat aactgccgac acagagaaat accatcaaaa
    16261 tcgtgagtgt tgtcagcatt ttcaccggta tttggggctg tttcatcgct tcgccctcac
    16321 tcgccagagg atcagtgcca tcagcagtaa caacactact ggcagcgccc acaacaccag
    16381 agtctgaccc gttaacggtg ggttatagcg aacaaaatct ccgtagcgtt cggtcatcca
    16441 gccaatgatt tcgacttcac ttttcccctc ttccaccatg gtgtaaacct gatggcgcat
    16501 actgactgcc accggcgcat tggattccag taagttctga ttctggcact gcggacaacg
    16561 taactggctg gcaatattta acgcctgttc ctgttgttgc ggattagcga attgccaggt
    16621 gtctacaacc tgagcgcgcg caaaacaggt aaataacagc agtagcgtga gaagcccttt
    16681 attcatcgcg cttccttccc cgccatccgc ttaacaatgc gcccgcaatc atcaacaatc
    16741 ctccccccca gatccagcgc acaccgcttt gtacatacaa acgaaatgcg taacgatccg
    16801 ctccggtttt ctctcccatg accgcatacc agtcatggat gccgttccag cgaatcgagg
    16861 gttccatcat ttgctgacgg cgtgcttcgt aaaaacgccg ctccggcgtt aattcaccaa
    16921 tgcgttgctg atggtcaaac agtgccacta tcgctttttc gctggtgtaa ttgcctttgg
    16981 cttgcagatc gaggcgctca aaacggaagg tgtatcctgc cagcgtcacc tgctgacccg
    17041 gctgtaaatt caggctgatc tcctgacggc tgacgctgga aaccacgatc cccgcggcaa
    17101 ataacagcac gcccgcatgc gccagcagcg tcggaagccg cgcgcgtttg ccagagacaa
    17161 acgtcgccag cacaatcacc accagcatca acagagcaaa cggtaacgtc gcgcggttaa
    17221 aatacggcgc gccaacggag aggcgtcccc agcccagcag gccgtaaatc atcggataaa
    17281 gcgttcccac cagcacgatc agtagcactg cgcaaaacag caacagcgta gcgaggatta
    17341 acatttcccg cgataacccc gaaaaacgca ccgccgggcc accgtcccgc gctcgccagc
    17401 catacagagc cagagacgca aggctaatca gtacaaacag gccgaacaac ggcacggcgc
    17461 ggacgttatc cagcgcgaac gcatgaaccg aaaccagaat gccagaacgg acaatcaacg
    17521 tgcccagcag cgacagcatc agagtaacta tcgtcagcaa cagcgaccag tggcggaaaa
    17581 tcccccgctg gcgtgtcagg gataaactgt gcagcagcgc tgtggcagaa agccagggta
    17641 gtaaagaggc gttttccacc ggatcccaga accaccagcc gccccagccc agttcgcaat
    17701 aggcccacca ggaaccgagg atgatccccg ctgttaatgc gctccagcca ggtagtgccc
    17761 aacgccagca aattcgggcg caggtaccat caaactcgcc gcgcagtaaa ctcgccagcg
    17821 ccacgctcgc cgccaccatc aaaccgccgt agccgagata aagcagcggt ggatgaaaga
    17881 taagaccggg atgttgcagc atcggattga gatcgcggcc ttcgattgct ggtggaaata
    17941 tccgcacgaa gggatcggac cacagcacca caaacagtag cagtgcggcg agcatgagag
    18001 ataaaacggc tagcgtcagc ggaaatagcg gatcggtttg ctgccggtaa tgccaggcaa
    18061 acagcgcgct ccaggcggaa agcagcagca cccaaagcaa cagcgaacct tcatgaccgc
    18121 cccacaccgc cgccagtttg agttcccacg acagcaggct atagctatgt tgggcgacat
    18181 aaataaccga gaaatcgctg atgagaaaac aatacgtcag tacgccaaag gcgagcagca
    18241 ggagcgcgaa ctgcgccaga atgccgatgc aagtgagtcg catcatggca ggccagcgca
    18301 accgcactcc cgcgaaggcc gtcaacggga tcaacacgtt gaccccgaga cttaacaaca
    18361 acgccagaaa accgacttca ggaaggaata cgtccagaaa ccacctctgt tctggcttac
    18421 gccaccgtta actgcccggc gtagagaatg aaaaagcgca gcatcaacac gccgaccagg
    18481 ctggccccac atgccgccag cacggcagga atgccggaac tgcgattgac ccacggtttg
    18541 agcaacattg gcacaatcag ccccagcccg gcgacaccaa gccagaacca ccacgtccag
    18601 aaaccgccgc ccaatgccgc caccagcgca cgcactttac cgtcatcgcc cagcgccaga
    18661 ccgacaaaaa acgccaccag caggaagatt tcaccccata ccacggggat ttccatacgg
    18721 tgtacaaagt gcgcttccgt ggaatgcggg ttactgcgtt ggcgtatcgc catggcgatc
    18781 agcgccaccg ccgcaccgga cgagatgccg gagaagagga acagcaccgg caggatcggg
    18841 ttattgagga acggatacga tttcagcgcc gacagcagaa agccggtata agcccccaac
    18901 aacaccgcca gcaccagcat caatgtttcc agtccgcgat gaacgggcgt cagcaggctc
    18961 aagacctttt gcacgatccc cagcttcggc aaccagcgtt gttgcagggc aagcaaatca
    19021 tgttcaaaga ttttcgccag ccacagcacc agcaccacca tgtaaagctg aaacagcatc
    19081 acccccatcg acatcaccga ggtaaaactg tagtggaaca tcagcttcca gaaggtccac
    19141 ggtcttgtca ggtggaagac gaggatcaac agaccgagga tcaccgcgcc aggcccgaca
    19201 atcagcgtgg tgcgcagcaa cgtactgtct gcaccgcctg cctgcgggta gaagcgacgt
    19261 aacagcacgg ccagtgtcac cagaccggca gaaataccaa tcaaaaacag gtagatggca
    19321 atcggccagt cccacaccag cgattcaaaa tgaaatgcgg aagtctgcgt cattggctca
    19381 cctccccgta tttaaacggt acgcggtaca gcttcggttt ggtgcccagc gccagcttgt
    19441 agcggtaagt gggcttctgg cgcagcagtt gcgaaatctc actgttggga tcgtccagat
    19501 tgccaaacgt cagcgccttc gtcgggcaag cttcaacgca cgcgggcagc ttaccggcct
    19561 gcaaatgggt cttacggcag aaatcgcatt tgtccgccgt cttcgtgacc ggatggataa
    19621 agcgcacgcg gtacggacag gcggcgatgc agtactgaca accgacgcag agatccggat
    19681 taacatcgac aatcccactg gcagcgtcgc gaaaagacgc accggtcggg cagacgtcaa
    19741 cgcacggcgc atgatcgcag tgctggcaag acttacggaa gaagcgatat ttcacatcag
    19801 gaaattcgcc ctgcggctcg ctacgaataa tcgtcaggcg cgagacgcct tccggcacct
    19861 tgttcacttt ccgacaagca tccatacagg cggtacagcc gatgcataac gactcgtcat
    19921 gcaccatgcc gtaacgcacc ccattgatat tcaacgtttt cgccaccacg cgccctgcgg
    19981 tgccgctgac ggcggccagc acaccgacgc cggtgagaaa ctggcgacga gaccaggtca
    20041 tggctgctcc ttaagcaacg gaacagacgc cgggttaaag ttcggattgg tgcgctgatc
    20101 gctgtggcaa tcgacgcaaa tcttaatccg tcctttgtca cttaacgtct gcatcgtatc
    20161 ttgctgtgga tgcagggaat ggcagctggc gcacgccact ttggttacgt ggacatcgtg
    20221 cggccagaat gctttttgca actgttccgg cagatggcag gacatacaga cgctgttctg
    20281 ctctccaacc ttgtacatcg gctcgttaaa gcgcatcaca tctttcaccc cttcgcggtg
    20341 ttgcggtgat ggctggccgt gacagttggt gcaggtgacc ggcagtttgt tattcgggtt
    20401 gataacggaa gcatgtttgc catgcatacc ttcggtatct ggcttatgac agtccagaca
    20461 ggcggcatcc gggttacgct gctgggtaac ttcgtagcga tcaccagatg cctgcgccgc
    20521 aggggtagcg gtaattccgt tcaggctcca caacaggccc gacgccagca ccccggcagt
    20581 taataacgaa cgtaatacgc tcatattcac tccattgtgt tttccgcccc ttgcgaggcg
    20641 gaacggggtt attggcttaa cagaccgttt ttacgtgcct gctcttccca ctgcgggatc
    20701 accgttttga tgaagtcctg cttctcggcc ttgatttgct ccatgttcag gccaatggcc
    20761 tgctgggctt tctctttggt cgagatatcc gggatctgga tttcatgggt aatgcctttg
    20821 gtcgccagca ggcgcgccag tttggtgcgt gcatccgccg ctttatccat cgccgtaccg
    20881 agcatcctca gaccttcttc cggtgcgtgc atatgaatgc cgtgggaagc gatcgccaaa
    20941 tcccaacgcc actgggcatg acggatatcg tcctgaatcg gcttcatttc ggcttccgtt
    21001 gcgcctgcat ccagcgccgc tttcgcttcg aagtgagcgt gaaccagttg atcttcaacc
    21061 ttgattttca ggtcgttaat cgactgctta cgttccgcga ccactttttg caaggcagct
    21121 ttgtcctggg tatggcagtt cgcacaagtc tgggcgaagt tatcaaacgg attaccaatt
    21181 ttatggtcgg tgtagagttt gccttcggcg ttctgcactt ttggcatatg gcaatcgata
    21241 caggtcacgt tgtttttgcc gtgaatgccc gctgtccagg tttcatattc cgggtgctgc
    21301 gctttcagca ttggcgtttt cgacagggag ttagtccagt cagagaaggc aattttgtcg
    21361 taatactgct ccatattttc gactttcatg ccgtcatccc acgggaattt aaccgctttg
    21421 tttttgccgt cgaagtaata ctccacatgg cactgaccgc aaaccatcga ttgctggtcg
    21481 aaacgtccgg ctttctcaaa aggtttacca atggcttcca tcgcgcgagc cgcatacgga
    21541 cgggaaaggg ttaactccgg tttgcctttg gcgaactctg gtgaggcggt gttatggcaa
    21601 tcggcacaac ctaagttgtt gacgatttcc gggccgccgc gcgcccattt accgtggaag
    21661 tagccatctt cgccgtcttt ctggatcaga cgcgccacat ccgggctttt acaactccag
    21721 cacgccatcg gtagcggacc atcttcagcg tttttcggcg caccggtacg caaggtttca
    21781 cgcacatcgg tcacagcaaa ggcatgtcca cgcggcttgt tgtaatcgcg cgagaaggga
    21841 taccccgccc acaggatcac cagccgtgga tcttccgcca gggcgtcaac acgctctgac
    21901 tgttccgagg tagctttcca ggagagatat tgatcgggat gctgcggggc aaaggtttca
    21961 ttcttcgctt ccacagttac aggtgttgcg ggagcagccg tttgttcagc gtgaacagaa
    22021 gtgaaaaaga aaaaaggaat caataagctg aagatacggc gtgcgtttat ttttatcctt
    22081 gtcatagggc ttcatccgaa ttgagccatt gttgcaatgg cggtttttat tgtttttcac
    22141 gacagtaacc gcacctacac tgtcatgaca ttgctcgccc ctatgtgtaa caaataacca
    22201 cactatgaat gttgtcttta atcaattgta agtgcatgta aaataccact ttagagttag
    22261 tcggtatctt cctctttttc aacaacatgc ataactgcat gttcctcaaa gaattaatca
    22321 acttttgttg ctgaccttca aaaattaccc tgccgtttat ttgcacaatt ctacttttgc
    22381 gtgatctgtc gcccaaatac taaacaaaac tgccaatacc cctacattta acgcttatgc
    22441 cacatattat taacatccta caaggagaac aaaagcatga gtcaaattca caaacacacc
    22501 attcctgcca acatcgcaga ccgttgcctg ataaaccctc agcagtacga ggcgatgtat
    22561 caacaatcta ttgacgcacc agataccttc tggggcgaac agggaaaaat tctcgactgg
    22621 atcacaccgt accagaaggt gaaaaacacc tcctttgccc ccggtaatgt gtccattaaa
    22681 tggtacgagg acggcacgct gaatctggcg gcaaactgcc ttgaccgcca tctgcaagaa
    22741 aacggcgatc gtaccgccat catctgggaa ggcgacgacg ccagccagag caaacatatt
    22801 agctataaag agctgcaccg cgacgtctgc cgcttcgcca ataccctgct cgaactgggc
    22861 attaaaaaag gtgacgtagt tgcgatttat atgccgatgg taccggaagc cgcggtcgcg
    22921 atgctggcct gcgcccgcat tggcgcggta cattcggtga ttttcggcgg cttctcgccg
    22981 gaagccgttg ccggacgcat tatcgactcc agttcacgac tggtgatcac ttccgacgaa
    23041 ggtgtgcgtg ccgggcgtag tattccgctg aagaaaaacg ttgatgacgc gctgaaaaac
    23101 ccgaacgtca ccagcgtaga gcatgtggtg gtactgaagc gtactggcgg aaaaattgac
    23161 tggcaggaag ggcgcgacct gtggtggcac gacctggttg agcaagccag cgatcagcac
    23221 caggcggaag agatgaacgc cgaagatccg ctgtttattc tctatacctc cggttctacc
    23281 ggtaagccaa aaggcgtgct gcacactacc ggcggttatc tggtgtacgc ggcgctgacc
    23341 tttaaatatg tctttgatta tcatccgggc gacatctact ggtgcaccgc cgatgtgggc
    23401 tgggttaccg gacacagtta tttgctgtat ggcccgctgg cctgcggcgc gaccacgctg
    23461 atgtttgaag gcgtaccgaa ctggccgacg cctgcccgta tggcgcaggt ggtggacaag
    23521 catcaggtca atattctcta taccgcgccc acggcgattc gcgcgctgat ggcggaaggc
    23581 gataaagcga tcgaaggcac cgaccgttcg tcgctgcgca ttctcggttc cgtgggcgag
    23641 ccaattaacc cggaagcgtg ggagtggtac tggaagaaga tcggcaacga gaaatgcccg
    23701 gtggtcgaca cctggtggca gaccgaaact ggcggtttca tgatcacacc actgcctggc
    23761 gctaccgagc tgaaagccgg ttcggcaaca cgtccgttct tcggcgtgca accggcgctg
    23821 gtcgataacg aaggtaaccc gctgaagggg gccaccgaag gcagtctggt gatcaccgac
    23881 tcctggccgg gtcaggcgcg tacgctgttt ggcgatcacg aacgttttga gcagacctac
    23941 ttctccacct tcaaaaatat gtatttcagc ggcgacggcg cgcgtcgtga tgaagatggc
    24001 tattactgga tcaccgggcg cgtggacgac gtgctgaacg tctccggtca ccgcctgggg
    24061 acggcagaga ttgagtcggc gctggtggcg catccgaaaa ttgccgaagc cgctgtggtc
    24121 ggtattccgc acaatattaa aggtcaggcg atctacgcct acgtcacgct taatcacggg
    24181 gaggaaccgt caccagaact gtacgcagaa gtccgcaact gggtgcgtaa agagattggc
    24241 ccgctggcga cgccagacgt gctgcactgg accgactccc tgcctaaaac ccgctccggc
    24301 aaaattatgc gccgtattct gcgcaaaatt gcggcgggcg ataccagcaa cctgggcgat
    24361 acctcgacgc ttgccgatcc tggcgtagtc gagaagctgc ttgaagagaa gcaggccatc
    24421 gcgatgccat cgtaacccac aattgtcgga tgcgctccga cctacatctg gcaacggctg
    24481 taggtcggat aagatgcgcc agcatcgcat ccgacaacaa gcgccggatg cggcgtgaat
    24541 gccttatccg gcctacattc ggcaagggtt acccaagcgt taaccttctc ccataaggga
    24601 gcgggaatta aaacaatccc tacattacct ctggagaatc tgtgatgaat ggtacgattt
    24661 atcagcggat agaagacaat gcgcatttca gggagttagt cgaaaaacgg caacggtttg
    24721 ccaccatcct gtcgattatt atgctggcag tttatatcgg ctttatttta ctgatcgcct
    24781 tcgcgcccgg ctggctgggc accccgctga atccgaacac cagcgtcaca cgcggtattc
    24841 cagtcggtgt cggggtaatt gtgatctcct ttgttctcac tggtatctac atctggcggg
    24901 cgaacggcga attcgaccgt cttaataatg aagtcctgca tgaggtacaa gcatcatgaa
    24961 aagagttctg acggcgcttg ccgccacact ccctttcgca gctaacgccg cggatgctat
    25021 tagcggggcc gtagagcgcc agccaacgaa ctggcaggcg attattatgt tcctgatttt
    25081 cgtcgtgttt acgctcggca ttacctactg ggcgtcaaaa cgcgtacgtt cgcgtaatga
    25141 ctactacacc gcaggcggca atatcaccgg ttttcagaac gggctggcga ttgccgggga
    25201 ctatatgtcc gccgcctcat tcttggggat ctccgcgctg gtgtttacct ccggctatga
    25261 cggcttaatt tactcgctgg gcttcctggt gggctggccg atcattctgt tcctgattgc
    25321 cgaacgtctg cgtaacctcg gtcgctacac ctttgccgat gtggcctctt accgtctgaa
    25381 acaagggccg attcgtattc tttcggcctg tggttctctg gtggtggtgg cgctttacct
    25441 tatcgcccag atggtgggcg caggtaaact gatcgagctg ctgtttggcc ttaactatca
    25501 cattgcggta gtgctggtcg gcgtgctgat gatgatgtac gtcctgttcg gcggcatgct
    25561 ggcgaccacc tgggtacaaa ttattaaagc cgtgctgttg ctgttcggtg ccagctttat
    25621 ggcctttatg gtgatgaaac acgtcggctt tagcttcaac aatctgttca gcgaagcgat
    25681 ggcggtacac ccgaaaggtg tcgacatcat gaagccgggc gggctggtga aagatcctat
    25741 ctccgcgctc tctttggggc taggactgat gtttggtacg gcgggcttgc cgcatattct
    25801 gatgcgcttc tttacggtca gcgatgcccg cgaagcacgt aagagcgtgt tctacgccac
    25861 cggatttatg ggctacttct acatcctgac ctttattatc ggctttggcg cgatcatgct
    25921 ggtcggtgcg aatccggaat ataaagacgc ggcgggccat ctgattggtg gtaacaacat
    25981 ggcagcagtt cacctggcca atgcggtggg cggcaacctg ttcctcggct ttatttcagc
    26041 ggttgctttc gccaccattc ttgcggtggt tgcgggtctg acgctggcgg gcgcatcggc
    26101 ggtgtctcac gacctgtacg ctaacgtctt caaaaaaggt gcgaccgaac gtgaagagct
    26161 gcgggtatcg aaaatcaccg tactgatcct cggtgtgatt gccattatcc tcggcgtgct
    26221 gtttgagaat cagaacatcg cctttatggt ggggctggcg tttgccatcg cggcgagctg
    26281 taacttcccg atcattctgc tttccatgta ctggtcgaaa ctgactaccc gtggcgcaat
    26341 gctgggcggc tggttaggac tgattactgc ggtggtgctg atgatcctcg gcccgacgat
    26401 ttgggtacag atcctcggtc acgaaaaagc cattttcccg tatgaatacc cggcgctgtt
    26461 ctctatcagc gtggcattcc tcggtatctg gttcttctcg gcaacggata attcagcgga
    26521 aggtgcgcgc gagcgtgaac tgttccgtgc gcagtttatc cgctcccaga ctggctttgg
    26581 cgttgagcag ggccgcgcgc attaatctct ccccttcccc ggtcgcttga tcggggaatt
    26641 tcttcagaac atcatcctgg ccaccagcgg cgaaaccaat accatcaata cacctgaaag
    26701 catcatgacc aggcttgcaa ctacgccttc ttgttgaccc agttcatacg accgcgcagt
    26761 cccggcacca tgagatgccg cgccgaatcc agcacctttc gccatccctt cgcgaataga
    26821 gagacgtaaa aacaacacgt cgccaatcgc catgccaaac acaccggtga ccaccacaaa
    26881 cagcgccacc agatcaggct gtccgccgag cgactggctc gctgccaaag caaatggcgt
    26941 agtgaccgaa cgcaccgcca ggctacgctg gatctcatct ggcagggtaa acaatcgcgc
    27001 cagccacact gagctggtca ctgccaccac cgttgccgtc agtacgcctg ccgtcaacga
    27061 catccagtga cgcttaatga tcgcccgatt gtcatacact ggtaccgcaa aggcgatggt
    27121 ggccggacct aatagccata gtaaccagtg cgcttcgcca atatagtttt gccaggaaat
    27181 attgccaaaa accagcagca taaccagtag cgtaggcgtc agcaccagag gcatcaatgg
    27241 caatttacga aagcggcgat aaaggcgttt gttaagaaaa tagataacta gcgtaattgc
    27301 cagacagagc atacttagct gaaaattagc cacggtttaa cctgcgcatt tcatagcgat
    27361 agactttttc cactacccag gcagtcgtgc ccagcaccat caccgtactc agcgcgatca
    27421 cagcaaaaat acgccagcca tccaccagta atagttgtgc atagttcacc acagccacca
    27481 cggcagggac aaaaaacagc aacatttcgg ccaatagcca acgcgccccg gctcgaaccc
    27541 attgcagagg aagaatgcga caaacaatca gcgccagcat caggatcatc cccaccaggt
    27601 tggcaggcag cggcaaatgc agccaggaga cgagatactg cgcaaaaata aataaacctg
    27661 catacagcac aacctgaaaa aatacctgga tagattgcac tacggcaggg gtaatgcggc
    27721 gaagcgccac gggcatgaga ggatatcctg aaaataaaac agaatggtaa gtatagagag
    27781 cgctcgcccc tgactgaaat gaattaaaat cattgcaggt atagtcaaag ggaatagtta
    27841 tggatatcag aacgctgcgt tattttgtcg aagtcgtgcg ccagcaaagc ttcacccgcg
    27901 cagcggagaa gttgtttgtc acccaaccaa ctatcagcaa gatgctgaag aatctcgaag
    27961 atgagctgaa ctgtatattg ttgatccgcg atggtcgtcg gctgcttctc actgatactg
    28021 gtcgcgtcgt atttgagcgc gggctggctt tactggctga gtttcggcaa ctggaagctg
    28081 agcttagcga tatcaatcag cttaaaaccg gcgttttgcg gctgggaatc ccgccgatgg
    28141 ttgggatgtt gatggccggg ccgattggcc tttttcgcca gcgttacccc ggcgtagaat
    28201 tgaaaatttc ggagtttggt ggtctgacgg tacaacaagc ggtgatgaac ggtgaactgg
    28261 atatggcact gacagccctg ccagtagaag aaagcggcct gacaacgtta tcgctgttta
    28321 gtcatccact atgtgtactg acgccacatt caggtaaatg gcttgaatgt gatgccgtct
    28381 caccggagac attggcggaa catcctctac ttatctataa cgaagatttt gccttaagta
    28441 agcaattgat gaagttattc gatgaacatg gcgttaagcc gagaattgca gttcgcagcg
    28501 ggcaatggga ttttctcgcc gcgatggttc aggccggtgt cggaatagcc atattgccgg
    28561 aacccatttg ccagcgatta gataaaaaca ccttaaaatg gctaccgctg gaaagcgaac
    28621 taagctggaa attaggaatg atttggcgtg agggcgttta cctttcccac tctgcccacg
    28681 cgtggctgag ctgttgtgaa ggatactggt taacgccaga gtaagtcggg ttggcgggct
    28741 cgcccgccaa ccatgcagat tactgatttt cctcaatcag caacgcttca agcaaatcga
    28801 gatcgtgcag taatttttgc agcgtttcgt tactgatctc ccgcgtggcg cgcaggtggt
    28861 acagttcagc acgttcagaa cgcaatgccg ccagacggaa gcgacgctcc aggttctctt
    28921 ccaggattga actttctaca tcattacgtc catcggcgcg acgacgcagg ttaccaatga
    28981 cgcgagaact aacctctgtg agcagctggt tatcgatatt ctcttcggta tccgccgcca
    29041 aacgctcctc cattttctgg atcgccacaa tcgccacttc tgccgttgcc gctcgtgcaa
    29101 tacgttcctc tttcaattgt tgcgaatggt ccgcgacttc tatgtgttgt agcagaatag
    29161 gcaacatcac cacgccgaca aacaacgaga agagaatgac gccagccgcc aggaacacca
    29221 actcatagcg cgcagggaag acgttaccat ccggcaagag aagcgggata gagagcacac
    29281 cggccagagt gatcgcccca cgcaccccgg cgaaagacgc gatcaggatt tctcgtgtag
    29341 tccacgaacc aaactccatc ggcttcttct tcaggaagcg gttgctgaac tttttcatcg
    29401 tccacagcca gccgaaacgg accagcatca gcgccgcata tatcagaata atatcggtaa
    29461 acagcatcca gatttcgacg ttaggatcga tttctgccgc catcagcgac gtctccagaa
    29521 tccccggcaa ctgcagacct aacagcagga acaccatgcc gttaaagaca aattccagca
    29581 tcgcccaggt gctgtttgcg cgcaggcgca ttgccagcgg cgcacggcgc atcacaccgg
    29641 agcgggtgat ggtcatcccg gcggcaaccg cagcgaggat gccggaaacg ccaatatgtt
    29701 ccgcaatcag ataagaagcg aatggcagca agaacagcag aacgatctgc gtcgcgggtt
    29761 catcaccgcc ccagcggctg aggaatcgca gcgagcgacc atacagccag ctcaccacaa
    29821 aaccggcgag aataccgcct attgccactt tcataaattc gaccgtcgca ccgccgacgg
    29881 tgaagatcat tgtccccatc gccactgcca cggcaaactt caacgacacc aggccggagg
    29941 cgtcattcat caacgcttcg ccctgcaaaa tgcccatgat ttttttcggg atgcgcccct
    30001 cgccaacaat cccggagagc gctacagcat cggtcggaga aagcaccgca gccagcgcaa
    30061 aggcggggat cagcggaatg cccggcacca cccagtaaat aaggaagcca atgccgacca
    30121 cggtgaccac caccagcgcc agcgcgaggc cgaaaatctc tcgcccatgt tcgagaaatt
    30181 cacgggtcgg cgttttccaa ccatcagcga acagcaacgg cgggataaac aagactaaaa
    30241 agagttcagg atcaaactcc acatgcaaac caaacgtcgg ccacgccagt agcgcaccga
    30301 tggcgatttg cataagcgga agcgggatct gaaagggcat gacacgagtg accaccccgg
    30361 acagcgagac cacgagggtc attatcagta tggtgaagaa gatttccatg cgttccctgt
    30421 ttgcgatgtt ttttatgatc tgagaaaggc gttatgcctg aattctcatt ttttcagaat
    30481 atcgcaaaag ctcacacaat gtgcggagaa aataaaaacg ggcagccatt gccacccgtt
    30541 ttcagaatcc tatgtaagat tagatagccc agccacccgc atagaaggtc accagcgcca
    30601 cggcaataac gaccgtaccg atgttcaact tgcgccattc gccggaaacc agacgaccaa
    30661 tcaccagagt cgcgaagcca atcatgatgc ctgttacgat gttacaggtc agcacgatga
    30721 ataccgccgt aaccagaccc gccatcgcat caacaaaatc agcaaagtcg attttcgcca
    30781 cgttgctcag catcagcagg ccaacgtaca tcagcgccgg agccgttgcg taccccggaa
    30841 cgaggtaaga gagcggagag aggaacagaa tcagcaggaa cagcacgcca acggtgatag
    30901 ccgtcaaacc ggttttaccg cccgccgccg tacccgccgc agactcgatg tataccgctg
    30961 ccggagctgc acccaccagg ccagaaaaaa cgctgctcat ggagtcggtg gtcagtgctt
    31021 tcccgccgtc gatgatctgc ccatctttat ccagcaggtt cgcctgaccg gcgacggcac
    31081 ggatagttcc ggtggcatca aatactgccg tcatcaccag tgccagaaca cttggcagga
    31141 ctacaggatt cagcgcgccc ataatgtcca ggctgcctat cagtgaattg ccgttttcat
    31201 cgctcaatga aggcatggcg aaaacgccgg agaaatggac gttaggatcg aagatcaaac
    31261 cgacaattga gataccgata atggtcagca gaatgccgcc agggactttc agtttttcca
    31321 ggccgataat cactgccagc cccaccaacg acatcatcac cggaaaggtc gtaaaatccc
    31381 ccagcgcgac gggcagacca tcaagcgggt ttttaatcac cagaccgaca ccattagcgg
    31441 caatgagcag caggaacaga ccgataccaa tccccgtgcc gtgcgccaca ccgtgcggca
    31501 agttgcgcaa aatccagcta cggatacccg tggcagaaat taccgtaaac agcacaccca
    31561 tcaggaacac ggcacccagc gcgacaggta cgctaatatg ttgccccagc accagactga
    31621 atgcggtaaa cgccgtcaga gagatggcgc aaccaatcgc caacggcaga ttagcccaca
    31681 gacccatcac gatagaaccg agtccggcaa ccagacaggt tgcaacgaaa actgccgcag
    31741 gcgggaagcc cgctttaccc aacatgcctg gaacgacgat aaccgagtag accatcgcca
    31801 gaaacgttgt taacccggca accacttcct gacggacagt gcttccacgt tgtgaaattt
    31861 taaaccaggc gtcgagtgaa ccgccggtac gcgctgatgg cgtagacata agaaaacatc
    31921 ccctgagagt ttaattttcg tcaagatgcg tggcggacaa tcccctgcca gcgaaacgtt
    31981 atcttcctgc tccaggtttg cgacaatttg ctgcgtcgca aaaaaagcaa acgtttagct
    32041 ccgcgcatac aaaacgggtg gtaaaaaaag caaacgatta tccggcgatc atagcggctt
    32101 tttcaaccga agtttgctgc ttttttctct tttattgtct tgacgatgaa aaaccaggca
    32161 attgatgcgc aaacgttatc gtcgatgcgc aagattgcag cgttatcgag ccgtataccg
    32221 ttcaggattg cgataaaaaa tcgtctgaga tgacaaaaat attgcggcta aaaagtgtac
    32281 ttttacactg gcgaagaaac gccggtaaca tacaattaaa gcatcaacac caaccggaac
    32341 ctccaccacg tgctcgaatg aggtgtgttg acgtcggggg aaaccctcct gtgtaccagc
    32401 gggatagaga gaaagacaaa gaccggaaaa caaactaaag cgcccttgtg gcgctttagt
    32461 tttgttcatc ttccagtaag cgtgcgccgg taccttcttc tcctaagcgg tcgcccgggt
    32521 tacgcaacgg gcaatcactg cgcgaaaggc agccacaacc aatacatcca tccagttcgt
    32581 cacgcagcgc cactaaggta tgaatgcgcc gatccaactc ttctcgccat tgggacgaaa
    32641 gctgtttcca ctctttcgca cttaacgtat gcccttctgg caacacgcca aacgcttcac
    32701 gaatggttgc gagcggaatg ccaatacgct gagcaatttt gataattgcg acatatcgca
    32761 acacatcacg tttatatcgc cgctgattgc cgctattacg gatactggta atcaaccctt
    32821 tgctttcata gaaatgcagc gccgataccg ccacaccgct gcgtttcgcc acttcgccgg
    32881 gtgttagcag cgctttaatg cggggtaatt tcttttccat aaatcgcttt acctcaagtt
    32941 aacttgagga attatactcc ccaacagatg aattaacgaa ctgaacactg aaaagaggca
    33001 gatttatgtc ccatcagaaa attattcagg atcttatcgc atggattgac gagcatattg
    33061 accagccgct taacattgat gtcgtcgcaa aaaaatctgg ctattcaaag tggtacttgc
    33121 aacggatgtt ccgcacggtg acgcatcaga cgcttggcga ttacattcgc cagcgccgtc
    33181 tgttactggc cgccgttgag ttgcgcacca ccgagcgtcc gatttttgat atcgcaatgg
    33241 acctgggtta tgtctctcag cagaccttct cccgcgtttt ccgtcggcag tttgatcgca
    33301 ctcccagcga ttatcgccac cgcctgtagt tttattgccc gcgcgttaat tcccgcgcgg
    33361 gtaattgctc catccattgc ataaacacct gcggcggcat cgccttcgcg aagaaccatc
    33421 cctggcaata gcgcacgccg cgtttgcgca gccagttaac ctgcgcctca gtttcgacac
    33481 cttcagcaat cgtttttaac cccaggctgt gcgccagctc gatgatgtgt tccgcaatca
    33541 aatgactggt tttgtgggtg gtcagcgtct caacaaacga tttatcgatt ttcaaaatat
    33601 cgacattcaa tgatttaagg ttatgcaagt tagagtagcc aataccaaaa tcatcaattg
    33661 ccacttcgta accggccttg cggaaagcca gaataatcgg cgtcattttg tcgacatcaa
    33721 gaaatgcatg ttcagtcact tcaaatttaa tttgctgcgg gcgcaccgca tgttgctctg
    33781 ttttctgatt ggttcgcgct atcaaccgtg aggtatgaaa atcggaggct gacaggttaa
    33841 tagaaacata gcgatcggca tgtgttgcca gatacgcgcc caaatcgcgg aagacattat
    33901 caataacata atcagttacc tgttcgatca tcccctcctt ttctgccagc ggaataaact
    33961 ctgccggatt cattacttgc ccctgctcac cgggccaacg taacaacgct tcagcgccga
    34021 tacatttttc tgttttgata tcgattattg gctggtaata aaggaaaagt tgatgttttt
    34081 cgagggcgcg ttgcaatttg cgtttgggag acaaatagtt ttgtcgaata cgtagccaga
    34141 gtaatagcag aacaagactc cccaaaatac cggcgggcaa cgcaaaaata agatgattat
    34201 aaaaatgggt tataagacgt tgatatgaag tcgcaacaat ggccgcaatt gggcgttttg
    34261 tcgaataaac tgtcgcatat aaatagccat ttcgttgtac ggttaaatca ttcaaacgaa
    34321 tcagcggaga aaacgttgct gccgaggcct cgttgcttaa cgagaaaaag gttttcgtca
    34381 ccgtatcata cacaccccat tgcaatgtcg gatcatcaga catcacttca ctccagaaga
    34441 gagggttaat gaccgctaca taattccccc gctgcatata ggtcatttta tagcctgaga
    34501 aaaaaggcgt atcacggtaa taatagatag aaacgttagg ttcacgctta taatcggccg
    34561 gtgcaatcgt atagccattt acagacgcta tcagcgatga gcataaaaaa tggttatcac
    34621 gagcataaat caattcatta atataaagat agccacgaat aatattcaac attcgctttt
    34681 gatgggctgg agtgcaaact tgcccctgat agcgttcagc tgcatcgctc actaaatctg
    34741 cctgacgaat gaccagctca gatttatcca acgccagctg agcaaaagtt cggagctgat
    34801 tattcacttc tgattttgcc caaaagaagg caatccatag cgacagaatg atgggaaaga
    34861 gaactaaaaa gataatgccc ggaaacgcca gtaattggtg tcgtgcacga tgactcattg
    34921 ctatcaattc cctgcctgtt tatacccggt tattgcaagg tgaaaccctg gctaccgacg
    34981 tctttagata aatcttacgg tataaatagc acttttgcct gatataaaat tgagaccttt
    35041 ttaatcgtca ccaggatgac gataattcat tgatcttaaa aattaatcac cttcaggaat
    35101 gcagaggcgg cgggaagata tacccttaat gccgctgaaa aaacacataa tctgtacggc
    35161 aataaaagtc acggcctaat ctggctaaca aacaaccaat tgtgatatag ttcacaaaat
    35221 tcatgaaaca aacagagtgt ttcatttttg tgttctgcaa gccccgcgat agccagagtg
    35281 tatcacgcct cccgtgaaca acgccgcgct gtccagggca tcagctcttt ttcgaggaat
    35341 tgtttgatgg ctaccctcac cactggcgtg gttcttcttc gctggcaact tcttagtgcc
    35401 gtaatgatgt ttctggccag cacgctcaac atccgttttc gtcgggctga ttatgtcggg
    35461 cttgcagtga tcagcagcgg tttgggcgta gtttccgcct gctggttcgc aatggggttg
    35521 cttggcatca caatggcgga tatcaccgcc atctggcaca acatcgagtc ggtgatgata
    35581 gaagagatga atcagacacc gccacaatgg ccaatgattt tgacttgata tgtagaagcc
    35641 tccataacgg aggcttcttt tttatggctg gcagatgctt taatcatcca ccttaaaaca
    35701 atatacccta ttgttttaaa gacaaatcag aacggaatat cgtcatcaaa gtccatcggc
    35761 ggctcgttag acggcgctgc cggagcggac tgctgcgggc gagactgcgc gccgccgctg
    35821 aactgattgc caccctgcgg ctgctgaggc tgaccccaac cgccctgcgg ctgaccacca
    35881 ccgatattgc cacctgcagg agcgccacca ccctgacgac cacccagcat ctgcatggtg
    35941 ccgccaacgt tcaccacgac ttctgtggta tagcgatcct gaccggattg atcggtccat
    36001 ttgcgggtac gcagctgacc ttcgatataa acctgagaac ctttacgcag atattcgctg
    36061 gctacttctg ccagtttgcc gaacagcaca acgcggtgcc attcagtctg ctctttcatc
    36121 tcgccggtgg ctttatcacg ccaggattcg gaagtagcca gcgtaatgtt ggcaactgcg
    36181 ccaccatttg gcatgtagcg tacttccggg tcctgaccca gattaccaac gagaataacc
    36241 ttgtttacgc ctctgctggc catgttcgtg tctcctgaaa aaaaatcgtt ctgaataagt
    36301 gtaaacgcgc gattgtacca ttaccaatag cgcttttact atgttgtgac ctcggttccg
    36361 ggaaacaaac ctggccagac attgttacac aacactccgg gtaatgcatt ccaatactgt
    36421 atattcattc aggttaattt gtgtcataat taaccgtttg tgatcgccgg tagcaccatg
    36481 ccaccgggca aaaaagcgtt taatccggga aaggtgaatg gataagatcg aagttcgggg
    36541 cgcccgcacc cataatctca aaaacatcaa cctcgttatc ccccgcgaca agctcattgt
    36601 cgtgaccggg ctttcgggtt ctggcaaatc ctcgctcgct ttcgacacct tatatgccga
    36661 agggcagcgc cgttacgttg aatccctttc cgcctacgcg cggcagtttc tgtcactgat
    36721 ggagaagccg gacgtcgacc atattgaggg gctttctcct gccatctcaa ttgagcagaa
    36781 atcgacgtct cataacccgc gctctacggt ggggacaatc accgaaatcc acgactattt
    36841 gcgtctgctg tacgctcgcg ttggtgagcc gcgctgcccg gaccacgatg taccgctggc
    36901 ggcgcaaacc gtcagtcaga tggtggataa cgtgttgtcc cagccggacg gcaagcgtct
    36961 gatgctgctc gcgccaatca ttaaagagcg caaaggcgaa cacaccaaaa cgctggagaa
    37021 cctggcaagc cagggttaca tccgtgctcg tattgatggc gaagtctgcg atctttccga
    37081 tccgccgaaa ctggaactgc aaaagaaaca taccattgaa gtggtggttg atcgcttcaa
    37141 agtgcgtgac gatcttaccc aacgtcttgc cgagtcgttt gaaaccgcgc tggagctttc
    37201 cggtggtacc gcggtagtgg cggatatgga cgacccgaaa gcggaagagc tgctgttctc
    37261 cgccaacttt gcctgcccga tttgcggtta cagtatgcgc gagctggaac ctcgcctgtt
    37321 ttcatttaac aacccggcgg gagcctgccc gacctgtgac ggacttggcg tacagcaata
    37381 tttcgatcct gaccgcgtga tccagaatcc ggaattatcg ctggctggcg gtgcgatccg
    37441 tggctgggat cgccgcaact tctattattt ccagatgctg aaatcgctgg cagatcacta
    37501 taagttcgac gtcgaagcgc cgtggggcag cctgagcgcg aacgtgcata aagtggtgtt
    37561 gtacggttct ggcaaagaaa atattgaatt caaatacatg aacgatcgtg gcgatacctc
    37621 cattcgtcgt catccgttcg aaggcgtgct gcacaatatg gagcgccgtt ataaagagac
    37681 ggaatccagc gcggtacgtg aagaattagc caagtttatc agcaatcgtc cgtgcgccag
    37741 ctgcgaagga acccgtctgc gtcgggaagc acgccacgtg tatgtcgaga atacgccgct
    37801 gcccgccatc tccgacatga gcatcggtca tgcgatggaa ttcttcaaca atctcaaact
    37861 cgcaggtcag cgggcgaaga ttgcagaaaa aatccttaaa gagatcggcg atcgtctgaa
    37921 attcctcgtt aacgtcggcc tgaattacct gacactttcc cgctcagcag agacactttc
    37981 cggcggtgaa gcccagcgta ttcgtctggc gagccagatt ggtgcaggcc tggttggcgt
    38041 gatgtacgtg ctggatgagc cgtctatcgg cctgcaccag cgcgataacg agcgcctgct
    38101 gggtacgctt atccatctgc gcgatctcgg taataccgtg attgtggtgg agcacgacga
    38161 agacgcgatt cgcgccgctg atcatgtgat cgatatcggt ccgggtgcgg gtgttcacgg
    38221 cggtgaagtc gtcgcggaag gtccgctgga agcaataatg gcggtgcctg agtcgttgac
    38281 cgggcagtac atgagcggta aacgcaagat tgaggtgccg aagaaacgcg ttccggcaaa
    38341 tccggaaaaa gtgctgaaac tgacgggcgc acgcggcaac aacctgaaag acgtgacgct
    38401 gacgctgccg gtgggtctgt ttacctgcat taccggagtt tcaggttccg gtaaatcaac
    38461 gctgattaac gacacactgt tcccaattgc ccaacgccag ttgaatggtg cgaccatcgc
    38521 cgaaccagca ccgtatcgcg atattcaggg gctggagcat ttcgataaag tgatcgatat
    38581 cgaccaaagc ccaattggtc gtactccgcg ttctaacccg gcgacctata ccggcgtgtt
    38641 tacgcctgtg cgcgaactgt ttgcgggcgt accggaatcc cgtgcgcgtg gttatacgcc
    38701 aggacgtttc agctttaacg ttcgcggcgg acgctgcgaa gcctgtcagg gcgacggcgt
    38761 gatcaaagtg gagatgcact tcctgccgga catttacgta ccgtgcgacc agtgcaaagg
    38821 caaacgctat aaccgtgaaa cgctggagat taagtacaaa ggcaaaacca tccacgaagt
    38881 gctggatatg accatcgaag aggcgcgtga gttctttgat gcggtgccag ctctggcacg
    38941 taagctgcaa acattgatgg acgttggtct gacgtatatt cgtctgggtc agtccgcaac
    39001 cacactttct ggtggtgaag cccagcgcgt gaagctggcg cgtgagctgt caaaacgcgg
    39061 caccgggcag acgctgtata ttctcgacga gccgaccacc ggtctgcact tcgccgatat
    39121 tcagcaactg ctcgacgtac tgcataaact gcgcgatcag ggcaatacca ttgtggtaat
    39181 tgagcacaat ctcgacgtga tcaaaaccgc tgactggatt gtcgacctgg gaccagaagg
    39241 cggcagtggg ggcggcgaaa tcctcgtctc cggtacgcca gaaaccgtcg cagagtgcga
    39301 agcttcgcat acggcgcgct tcctcaagcc gatgctgtaa tcgttaaggc cgctttctga
    39361 gcggccttct tctttcagag ttgcaccagc aatttacgtt tttcttccgg cagcaaattc
    39421 accgcctgct gataagacgc atccaccaga taatagattt gcgaatccgg cagcgatccg
    39481 tcgagataca cggtgctcca gtgtgctttg ttcagatggc ggcttggacg cacatcgctg
    39541 tgctgctgac gtagcagctc cgccagctcc gggctggttt tcagcgaaac agctgggcga
    39601 ttttctactt ctttcaccat cgcaaacagc acatcttcca ctttgatctg cgtcgctttc
    39661 cagtcgttat gcacgctctg ttctgcgcct ggttttgcca tgcaatattg tagcaactcc
    39721 aaaatggtca ttttttactc cccttgaagt gtcgcgatga tgcgacgcga tccgccgtgg
    39781 atgcgatgtt cccccagcca gatgccttgc caggtgccgg tctgaatacg ccctttatgc
    39841 accggcaata caagcgatgt tcccagcatt gaggatttga tatgagaagg catatcgtct
    39901 gctccctcat agtcatgctc ataatttccg ttgtcgggaa cggcgcggag gaaaaaacgc
    39961 tccatgtcgt ggcgtacggt gggatcgcag ttctcattaa gtgtcagaga ggcggaggta
    40021 tgttgcagca acagatgcag taaaccgatg ttaacgcgcg gcatatcagc cagctgattc
    40081 agaatttcat ccgttaccag atgaaaccca cgagatttgg cgctaagcgt gagcgtcttt
    40141 tgataccaca tgtgctgctc cttgataaaa ctctcttaat cagtttgcag caagacagcg
    40201 aaaggataaa ggtgtgatta aaaaaacagc attcgggaga gtattacgct ctcccgctct
    40261 gtcagtattc tgaattgacg atcacctctt caccaaacgc acccgcttgt ggcaagggtt
    40321 tgtaggtaga gttggaggcg cgcagaatgc ggataccacg agcgccaaca tcgcgtgcgg
    40381 cggtaatatc gttatcggaa tcaccataaa aaattcggat atttttatcc tgcagccatt
    40441 gcgattttgt attttgacct ggtttatcgc ccgcaaagat caccggattc atgttggtgg
    40501 caggaatatg aaaattatcc gccagcgttt ttgaaaccgt ttctgttttg gtcgggctac
    40561 gaccagtcac aaagaagatc gcgtcaccgc ggcgtacatg catatcaatc agctggcgag
    40621 cgacctcttt tggaatgctg aattcatccc agccattgtt cattttttcc cagaacacag
    40681 gatttttcag ataatcttcg ctttctggtg agaaggtttt tttgccgcgc cagaaacccg
    40741 gactggaaaa aagtaccgta tcatcgatat caaaccccac cgccattggc ggacgtcctg
    40801 cgaggctatt ttcaatttgt gcaaccgaaa cccaatgaat tggtgcctgt tcagcgagtt
    40861 tggctacgtt agtacccgga ttaagcggtg aaggagatga ggccagggca acagcggaac
    40921 tgtttagagc gaacaataag caaacggcac tcaatgcctg tgtgatcttg cgcatatttt
    40981 tccctaaata gtcagtaagt tgaaacttat tattgtgcgt ttgttgaaaa aaccatctga
    41041 ccataacgcc aaccgcaggg gaaaggaagg attatctgcg gatttgtcac ataaaaagag
    41101 catgatcaca tttggaatac ctgtgcgata aaccacacat tgccacggtt attctgctta
    41161 cacattcaca caatggcact cttttggttc tcgcaaacat tgttcaggga atatactgat
    41221 gataaatata aatgcattca atggatgatg aatgaaaata tcgtggaatt atatatttaa
    41281 gaacaaatgg cgatttcaca ttacaagcat ttcacttttt cttatcatgc tcgcggtttc
    41341 aatcgctttt ttgcacttgc gttttaatac cttgtccggt accgataaaa tgcggcttga
    41401 aatgtataag tccacattat attccaccat cgagcaattt tatgttttac cctatatgct
    41461 ctcaacagac catatcatcc gtcaggcggt aattacgcct gacgatatga cgtccagcga
    41521 actcaatcaa cgaattgcac atttcaatac tcaactcaaa accgcagcaa tatttattct
    41581 ggatacccaa ggtaaggcca tcgcttctag taactggcag gaccccggca gctatgtagg
    41641 gcaaaattat agctatcgcc cctattataa acacgccatg tctggcttaa atggacgctt
    41701 ttacggtatt ggtagcacta cgaatacacc gggattcttc ctctctacaa gtataaaaga
    41761 taaaggaaaa attgtcggtg ttgtagtagt aaaaataagt cttaatgaaa ttgaaaaagc
    41821 atgggccgaa ggtcctgaaa atattatcgt gaatgatgaa catgggatta tatttttaag
    41881 ttcaaaatcg ccatggcgaa tgcgaacact gcaaccgtta cctgttcagg caaaacaaaa
    41941 actacaatct acccgccaat atagtctcga caatctttta ccggcggatt attatccctg
    42001 ttataccgtg agcaatttta ctttcctgaa agataaaaaa gaacaactct gtttattccc
    42061 gcaatattat acgcaacaaa tagccattcc agaatttaac tggaaaatga caattatggt
    42121 ccccttagat aacctgtact ggtcatgggc tatttcgtta gtcattacac taattattta
    42181 cctgctgttt ttgttattta ttaaatactg gagaatgcga tctcatgcac aacaattatt
    42241 aacactggcg aatgaaacat tagaaaaaca ggttaaagag cgtacatctg ccctggaatt
    42301 gatcaatcaa aaattaatac aggagataaa agagcgcagt caggctgaac aagtattaca
    42361 aattacgcgt agtgaactgg cagagtccag caaactggcg gcgcttggac agatggcaac
    42421 cgaaattgcc catgaacaaa atcaaccgtt agccgccatt cacgcactta ctgataacgc
    42481 gcgtactatg ctaaaaaaag agatgtatcc acaggttgaa cagaatctga aacacattat
    42541 ttccgtgatt gagcggatga cgcagctcat ttccgaactt aaagcatttg cctcgcgcca
    42601 tcgcgtacct aaaggttctg ccgatgtcat caaagtgatg tatagcgccg tggcgttact
    42661 taatcacagc atggagaaaa ataacattga gcgacgaata aaagccccat ccatgccgtt
    42721 atttgtcaat tgcgatgaac tcggtcttga acagatattc agtaatttaa ttagcaacgc
    42781 cttagattct atggaaggta gctcttacaa acgactggat atcgccattc gccaggcaaa
    42841 taacaaagtt attattacca ttaaagacag cggtggcggt tttgcacctg aagttgtcga
    42901 tcgcatattt gaaccatttt ttaccactaa acgtagagga atggggttgg gactggcaat
    42961 agtcagcgaa attgtccgaa attcgaacgg cgcactccac gccagtaatc atcctgaagg
    43021 cgacgcagta atgacattaa cctggcctga atggggagaa aaacatgaat aataaattca
    43081 gtgaaattac tatagtttat attgaggata gtgacgatgt acgttttgcc tgtgaacaaa
    43141 cgctcacgct ggctggttat cgcgttattt cctgttgcga tgcagaacac agtattcccc
    43201 ttattcaaag tcaggccaac attattatac tgaccgatgt caggttacct ggaatatcag
    43261 gactagagct cctcagttac atcaacgaaa tggatagcaa aattccggtt attttaatta
    43321 ccggacacgg tgacgtggaa atggcggtgg atgccatgcg taatggtgca ttcgatttca
    43381 ttgagaaacc aagtagctca gataaattat tgagtattat tgccagagcg gtagaaaaac
    43441 ggcgattggt tttagaaaat cagcaattac tggcgaatct gcaacaggaa aatggcccgg
    43501 tgctgattgg tcgtagtccg cagatgcagc aactgcgtaa aatgatcctt aatgtcgcag
    43561 ataccggtgc cgatgtcctt atttatggtg aaacaggttg tggtaaagaa gtcgtcgcca
    43621 gaatgctgca tcactggagt acccgccgtc aggggcagtt tgttgcctta aactgtgcag
    43681 gcttaccaga aacgttgttt gaaagcgaaa tatttggtca tgaggcgggc gcatttaccg
    43741 gtgcggttaa aaagcgtatt ggaaaaattg aacatgcaaa tggtggtacg ttatttctcg
    43801 atgaaataga gggaatgcca tcaggaatgc aggtaaaact gctacgtgta ttgcaggaaa
    43861 gaaccattga acgattaggt gccaatcaat taattccggt gaattgccgt gttattgcag
    43921 cgaccaagga agatttactg cgtcgcagcg aagaacatct gtttcgtctc gatctctatt
    43981 atcgtctgaa tgtggttagc ctgaatattc cacctctacg ccagcgacga gaagatatcc
    44041 ctgaactgtt ttactggttc gccagtcagg cggcacaaaa atataatcgt cctctgcctg
    44101 atatttctcc catgttactg gcctggttgc agtcacaaag ttggcctggc aatgtacgtg
    44161 aacttaaaca caatgcagag cgttttgttc tcggtttact gacccaccac cagccagtgc
    44221 caatgactca gcaagaagag agtggtctta ccgcctgcat tgatgctttc gagaaaaagt
    44281 taatcgaaga tatgctgcga caaacggaag gccaggtcag tttgacagcg cggctattac
    44341 agctgccgcg caagacttta tatgacaaac tcaacaaaca tcagattcaa ccgcaagttt
    44401 atcgaccaga atcatccagc taatgctgat tcctgaggat gtaaccccaa atcgatacct
    44461 ttgcgggcgt aatgttcaac tacccaggac cagaatgata ccgggatcgt aatcatcttc
    44521 gcattgcgtt cccggttggc agcttctggc ataccggggt aaatcaccgg attgccgcca
    44581 ggttgaggct gcgtagctaa cagataatcc gcaaagaact gccctttctc ccctgccaga
    44641 tcggtgaatt gatcaggatc gataatcaac gcaaaaagat gattatgcgc agatccatcc
    44701 gtctgatgat cttcggcgat cgtgtcacca ccagataaga tccccgccat catttcaatc
    44761 atcagtgcca ggccaaatcc tttatgctca ccaaatggca gtaacgcccc tggaggattg
    44821 ctgaataaca ccccaggatc attgcttgga ttcccctgtg catcaatcaa ttgtcccggc
    44881 gcggcctgct tcccggtgga cgacattacc cgtgctttat ttagcgccat gctactggtg
    44941 gcaaaatcaa ccagaatcgg cggacgccca tcactgaacg gccaggcaaa gcagaaaggg
    45001 ttagtggtca tacgcggttc cgcaccgccc cacggggcga ccagtgcagg acgcccggtg
    45061 acgttactca tggccagcat cgccaggcct tgatcagcaa ccatttgccc gtaatgcccc
    45121 atacgcccta aatgatgcgc atggcacaac gttaacaggc aaaaaccgcg gtgttttgtt
    45181 tgttcgatgg cagcatttac cgccactttt ccggcgtgtt gaccaaagcc attgtgggca
    45241 tgaaaacgct gtaaattacc ttcacttgtt aagcattccg ggcgggcatt cgcggttaca
    45301 tcgccacgag cgatattttc cagatatttc ggtagcagcg tgacgccgtg gctggcaaag
    45361 ccataacgtt ccgcttcaat catatgttcc gccacatcct gagcgatatc ggcatcacag
    45421 ccattaagtt ccagcagccc ggcagctaac caacgcactt tttcaacagc aatttgtaat
    45481 gacatcgttg gtttcctcac attagaccta aaattttcca ccaggtggcg gcaaacagta
    45541 gcaacaacag gtagccgatt accgtcaggt acagtcccac acgggtaaac tggcgtggcg
    45601 tgaaggtatc cgtacccata cacaccatat tttgtggcgc gttaatcggc aggatgaagc
    45661 caaaactgac actgaaggcg agcagaatgg tcatgccgac cgggttaacg ccgagttctg
    45721 gcggcagact gcttaacagg ctaatcagga tgggcagcaa tgcggcagtt agcgcagtgg
    45781 cactggcaaa ccccaggtga atgattatca agaaagcggc gagaatcgcg aagatggcaa
    45841 gtgatggtaa accgtcaaga ccaaaacctt tcaccacata gttcgccatc catgaagctg
    45901 cctgtgtatc aagcaacgtg gaccccaggc tgataccaat accaaacatc agcaacgtgc
    45961 cccactgcac acgtttttcg acctctttcc agctcattac accgatgcct ggcagcaaca
    46021 taatcgccag tccggcaagg gtgacagagg tggtatcaat actgtgtaat tttccgccag
    46081 tagaccaaaa gagcagtaac aacagcgaaa taccgatcaa gcgtttttct ttaccggtgg
    46141 ttggccctaa ctctgcgagt gcttttttaa tggcctcgct ccccccttca acagcttccg
    46201 tttctggcgg caacaattta cgtgcgagga aatagaggat caccgacatg gtgaggctcc
    46261 agggcgcgcc cgctaacagc cagtcaagcc agctgacaga atgcccggcg ccgaaagttt
    46321 tattgataaa accgatagaa agcaggtttt gcgccgacga agtttgaata ccaacgttcc
    46381 agatactggt cgcctgggcg ataacaatca tcattgacgc cgctaaacgt gaatgtttat
    46441 ccaccttaaa tgccgcaatg acccccatca taatcggcac cacgcaagcc gtacgggcag
    46501 tggcactggg tacgaccagg ctcaggacga tggtcaccac aatggcaccg ataataatgc
    46561 tgcggctact ggcacctatt ttcgacatag taaacagcgc aatacgttta tccagcccgg
    46621 taatggtcat tgccgccgcg ataaacattg ctgctgccac cagcgccaga gcagaattag
    46681 aaaaacccga cagagtcatt ttcagcgctt tcgcggtgcc aaggatcgtg tccgggtgat
    46741 tcatatccgg ggcaaaacca accataaaga taatcagtgc ggaaataaca attgcactgg
    46801 cggtgtaatc catcgcttcg ctgatccaga caataatggc aaacaccaga atggcgatca
    46861 tattttgtcc ggcgacgggc aaggtatcgc ccagaggcag aagagtaata ataattccgg
    46921 caatgatcgc caaccacagg ccgggattag ggataattcg acgcttttgt ggtgcgccat
    46981 gtgatattga tgacatattc acctcattgt gaaaaataaa aaacctgcct ggctattgca
    47041 ggagctatgc catctttaat tttttaataa tgctttgtta tt
//
LOCUS       DAPOXO010000033        44958 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPOXO010000033 DAPOXO010000000
VERSION     DAPOXO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 44958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44958
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.033"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..158
                     /locus_tag="ROH59_002234"
     CDS             <1..158
                     /locus_tag="ROH59_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4804714.1"
                     /translation="IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG
                     DGVQELN"
     gene            387..977
                     /gene="uidR"
                     /locus_tag="ROH59_002235"
     CDS             387..977
                     /gene="uidR"
                     /locus_tag="ROH59_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator UidR"
                     /protein_id="HDX4804715.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            1367..3178
                     /gene="uidA"
                     /locus_tag="ROH59_002236"
     CDS             1367..3178
                     /gene="uidA"
                     /locus_tag="ROH59_002236"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HDX4804716.1"
                     /translation="MLRPVETPTREIKKLDGLWAFSLDRENCGIDQHWWESALQESRA
                     IAVPGSFNDQFADADIRNYVGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQ
                     EVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSY
                     FHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRD
                     ADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYLLRVGIRSVAV
                     KGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYA
                     EEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAI
                     KELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCD
                     AHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVD
                     TLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGN
                     KKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ"
     gene            3175..4547
                     /gene="uidB"
                     /locus_tag="ROH59_002237"
                     /pseudo
     CDS             3175..4547
                     /gene="uidB"
                     /locus_tag="ROH59_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416133.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide transporter"
     gene            4586..5852
                     /gene="uidC"
                     /locus_tag="ROH59_002238"
                     /pseudo
     CDS             4586..5852
                     /gene="uidC"
                     /locus_tag="ROH59_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416132.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide uptake porin UidC"
     gene            complement(5897..7405)
                     /locus_tag="ROH59_002239"
     CDS             complement(5897..7405)
                     /locus_tag="ROH59_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HDX4804717.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKVNPWIKSGQSVIFNESVDHGPFP
                     LAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATELMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYANGQITLNGQKMPLEDFVGMFAMPTLNVPAVPAIPQQ"
     gene            complement(7506..8681)
                     /gene="manA"
                     /locus_tag="ROH59_002240"
     CDS             complement(7506..8681)
                     /gene="manA"
                     /locus_tag="ROH59_002240"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HDX4804718.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVHDAAGDIVSLRDVIESDKATLLGDAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     RNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
                     VAGAHPAIAHFLQQPDAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANKLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETT
                     ISQQSAAILFCVEGDATLCKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            8880..10526
                     /gene="fumB"
                     /locus_tag="ROH59_002241"
     CDS             8880..10526
                     /gene="fumB"
                     /locus_tag="ROH59_002241"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDX4804719.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILCDPEASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            10669..12072
                     /gene="fumC"
                     /locus_tag="ROH59_002242"
     CDS             10669..12072
                     /gene="fumC"
                     /locus_tag="ROH59_002242"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HDX4804720.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLSEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DRWVRPEQMVGSMKAGG"
     gene            complement(12069..12998)
                     /gene="tus"
                     /locus_tag="ROH59_002243"
     CDS             complement(12069..12998)
                     /gene="tus"
                     /locus_tag="ROH59_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HDX4804721.1"
                     /translation="MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNFSQAALVSHIQHINKLKTTFEHIVTVESELPSVARFEWVHRHFPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(13074..14375)
                     /gene="rstB"
                     /locus_tag="ROH59_002244"
     CDS             complement(13074..14375)
                     /gene="rstB"
                     /locus_tag="ROH59_002244"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HDX4804722.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLSERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLAQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            complement(14379..15098)
                     /gene="rstA"
                     /locus_tag="ROH59_002245"
     CDS             complement(14379..15098)
                     /gene="rstA"
                     /locus_tag="ROH59_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HDX4804723.1"
                     /translation="MNTIVFVEDDAEVGALIAAYLAKHDMQVTVEPRGDRAEETILRE
                     NPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATVTKGIQETSLTPYKALHFGTLTIDPINRVVSLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAA
                     EPYRIKTVRNKGYLFAPHAWE"
     gene            15227..15562
                     /locus_tag="ROH59_002246"
     CDS             15227..15562
                     /locus_tag="ROH59_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HDX4804724.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLASLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            complement(15559..16281)
                     /gene="folM"
                     /locus_tag="ROH59_002247"
     CDS             complement(15559..16281)
                     /gene="folM"
                     /locus_tag="ROH59_002247"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HDX4804725.1"
                     /translation="MGKTQSLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAI
                     DGLIKAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLTDVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSLPLDGGRHLR"
     gene            complement(16318..17700)
                     /locus_tag="ROH59_002248"
     CDS             complement(16318..17700)
                     /locus_tag="ROH59_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX4804726.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            complement(17886..18830)
                     /locus_tag="ROH59_002249"
     CDS             complement(17886..18830)
                     /locus_tag="ROH59_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX4804727.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            19354..20886
                     /gene="pntA"
                     /locus_tag="ROH59_002250"
     CDS             19354..20886
                     /gene="pntA"
                     /locus_tag="ROH59_002250"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HDX4804728.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQTAQKAAPEVKTE
                     EKCACSPWRKYALMALAIILFGWMASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            20897..22285
                     /gene="pntB"
                     /locus_tag="ROH59_002251"
     CDS             20897..22285
                     /gene="pntB"
                     /locus_tag="ROH59_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HDX4804729.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALIVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(22310..23344)
                     /gene="tqsA"
                     /locus_tag="ROH59_002252"
     CDS             complement(22310..23344)
                     /gene="tqsA"
                     /locus_tag="ROH59_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
                     /protein_id="HDX4804730.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIA
                     VILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIM
                     TPLQAIEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
                     MLLEVPQLPGKFQQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSI
                     AVLLSDLNKE"
     gene            23756..24121
                     /gene="mdtJ"
                     /locus_tag="ROH59_002253"
     CDS             23756..24121
                     /gene="mdtJ"
                     /locus_tag="ROH59_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HDX4804731.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            24108..24437
                     /gene="mdtI"
                     /locus_tag="ROH59_002254"
     CDS             24108..24437
                     /gene="mdtI"
                     /locus_tag="ROH59_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HDX4804732.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(24476..25297)
                     /locus_tag="ROH59_002255"
     CDS             complement(24476..25297)
                     /locus_tag="ROH59_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HDX4804733.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVAKSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(25397..25480)
                     /locus_tag="ROH59_002256"
     CDS             complement(25397..25480)
                     /locus_tag="ROH59_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804734.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            complement(25573..25908)
                     /locus_tag="ROH59_002257"
     CDS             complement(25573..25908)
                     /locus_tag="ROH59_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HDX4804735.1"
                     /translation="MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETATTPAPTATTT
                     KAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQP
                     AKPAAQPAA"
     gene            complement(26305..27558)
                     /locus_tag="ROH59_002258"
     CDS             complement(26305..27558)
                     /locus_tag="ROH59_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4804736.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNHFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTARYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHHRLHA"
     gene            27665..28558
                     /locus_tag="ROH59_002259"
     CDS             27665..28558
                     /locus_tag="ROH59_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4804737.1"
                     /translation="MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQ
                     IGARLLARTNRSVLLTEAGKQFLVDSRQILSMVDDAAARAERLHQGEAGELRIGFTSS
                     APFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPETLEH
                     AVIVHEPLMAMIPHDHPLANNPSVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYNL
                     TPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWP
                     KHHEQSPAARNFRIHLLNALR"
     gene            28693..29913
                     /gene="mlc"
                     /locus_tag="ROH59_002260"
                     /gene_synonym="dgsA"
     CDS             28693..29913
                     /gene="mlc"
                     /locus_tag="ROH59_002260"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor Mlc"
                     /protein_id="HDX4804738.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEESQELALKDDSPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            30038..30733
                     /gene="bioD"
                     /locus_tag="ROH59_002261"
     CDS             30038..30733
                     /gene="bioD"
                     /locus_tag="ROH59_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDX4804739.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TDKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(30686..31978)
                     /gene="clcB"
                     /locus_tag="ROH59_002262"
     CDS             complement(30686..31978)
                     /gene="clcB"
                     /locus_tag="ROH59_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HDX4804740.1"
                     /translation="MHHLHIYPDLRTMFRRLLIATIVGILAAFAVAGFRHAMLLLEWL
                     FLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQ
                     TDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWI
                     ACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDAL
                     LYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGG
                     LIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVF
                     TPTLFIGLAIGMLYGRSLGLWLPDGEEITLLLGLTGMATLLAATTHAPTMSTLMICEM
                     TGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS"
     gene            complement(32139..32753)
                     /gene="dmsD"
                     /locus_tag="ROH59_002263"
     CDS             complement(32139..32753)
                     /gene="dmsD"
                     /locus_tag="ROH59_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HDX4804741.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTNDGWET
                     QWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMKQNEPEDNFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR"
     gene            complement(32796..33650)
                     /locus_tag="ROH59_002264"
     CDS             complement(32796..33650)
                     /locus_tag="ROH59_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HDX4804742.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQHII
                     RGMFFLWLLMGIGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLVSMALGIIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAATILRAARVTFNTTPFAIISILALIACAGLIVLQGLSLASIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLVLGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            complement(33652..34269)
                     /gene="dmsB"
                     /locus_tag="ROH59_002265"
     CDS             complement(33652..34269)
                     /gene="dmsB"
                     /locus_tag="ROH59_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDX4804743.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            complement(34280..35849)
                     /locus_tag="ROH59_002266"
                     /pseudo
     CDS             complement(34280..35849)
                     /locus_tag="ROH59_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
     gene            complement(35910..38336)
                     /locus_tag="ROH59_002267"
     CDS             complement(35910..38336)
                     /locus_tag="ROH59_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HDX4804744.1"
                     /translation="MSKNEQMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRSAAAAV
                     QQASEKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDKYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGE
                     GDDKTAKTPQWASQITGIPVDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSKLAEIARTWELEKDEVISPLPVYASTFEGWDSPER
                     STFPLQLFGFHYKSRTHSTYGNIDVLKAACRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
     gene            complement(38535..38840)
                     /locus_tag="ROH59_002268"
     CDS             complement(38535..38840)
                     /locus_tag="ROH59_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HDX4804745.1"
                     /translation="MKHSTYCAALLLALASPTVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSTQDGAPAEPQ"
     gene            38948..39658
                     /locus_tag="ROH59_002269"
     CDS             38948..39658
                     /locus_tag="ROH59_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HDX4804746.1"
                     /translation="MKYKLLPCLLAILLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTLVALVLDANYYRDAET
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDNHANPVDCQLIIVDEG
                     VKPAVERVYTIKNTIDYY"
     gene            complement(39661..40221)
                     /gene="speG"
                     /locus_tag="ROH59_002270"
     CDS             complement(39661..40221)
                     /gene="speG"
                     /locus_tag="ROH59_002270"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HDX4804747.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFTVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(40256..40597)
                     /locus_tag="ROH59_002271"
     CDS             complement(40256..40597)
                     /locus_tag="ROH59_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HDX4804748.1"
                     /translation="MKITLSKRIGLLAFLLPCALVLSTTVHAETNKLVIESGDSAQSR
                     QRAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVIIP"
     gene            40732..41058
                     /locus_tag="ROH59_002272"
     CDS             40732..41058
                     /locus_tag="ROH59_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HDX4804749.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            41264..42478
                     /gene="rspA"
                     /locus_tag="ROH59_002273"
     CDS             41264..42478
                     /gene="rspA"
                     /locus_tag="ROH59_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HDX4804750.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGEKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            42490..43509
                     /locus_tag="ROH59_002274"
     CDS             42490..43509
                     /locus_tag="ROH59_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HDX4804751.1"
                     /translation="MKSILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPL
                     GEIFDEKGIQPTLVIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            43567..44934
                     /gene="ydfJ"
                     /locus_tag="ROH59_002275"
     CDS             43567..44934
                     /gene="ydfJ"
                     /locus_tag="ROH59_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter YdfJ"
                     /protein_id="HDX4804752.1"
                     /translation="MTIEKHERSTKDLVKAAVSGWLGTALEFMDFQLYSLGAALVFHE
                     IFFPESSTAMALILAMGTYGAGYVARIVGAFIFGKMGDRIGRKKVLFITITMMGICTT
                     LIGVLPTYAQIGVFAPILLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSFVA
                     MGTNCGTLSATAIWAFMFFILSKEELLAWGWRIPFLASVVVMVFAIWLRMNLKESPVF
                     EKVNDSNQPTAKPAPAGSMFQSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTLLFNK
                     AIPTDALMISSILGFMTIPFLGWLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYA
                     PSTIMVALIVIHNCAVLGLFALENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPIL
                     AGIFCTMTESWYPIAIMIMAYSVIGLISALKMPEVKDRDLSALQDAAEDQPHVVRAAQ
                     PSRSL"
BASE COUNT        11303 a        10790 c        11555 g        11310 t
ORIGIN      
        1 aaattgaaca gaaaatgttg caacacacac caatcagacg tctgggccaa ccgcaagata
       61 ttgctaacgc ggcgctgttc ctttgttcgc ctgcagccag ctgggtaagc ggacaaattc
      121 tcaccgtctc cggtgatggg gtacaggaac tcaattaata cactaacgaa ccggtaaaca
      181 gccgtatgtg ttgtttaccg ggatagcgtg tgcaactcgt caacgtctct gctaaacaac
      241 tggcagccaa atcacggcta ttggttaacc aatatctgga taaaaagctt acgaattgag
      301 tgtgccttcg cactattcaa cagcaatgat aggcgctcac ctgacaacgc ggtaaactag
      361 ttattcatgc taactataat ggtttaatga tggataacat gcagactgaa gcacaaccga
      421 cacggacccg gatcctcaat gctgccagag agattttttc agaaaatgga tttcacagtg
      481 cctcgatgaa agccatctgt aaatcctgcg ccattagtcc cgggacgctc tatcaccatt
      541 tcatctccaa agaagccttg attcaggcga ttatcttaca ggaccaggag agggcgctgg
      601 cccgtttccg ggaaccgatt gaagggattc atttcgttga ctatatggtc gagtctattg
      661 tctctctcac ccatgaagcc tttgggcaac gagcgctggt ggtcgaaatt atggcggaag
      721 ggatgcgtaa cccacaggtc gccgccatgc ttaaaaataa gcatatgacg atcacggaat
      781 ttgttgccca gcggatgcgt gatgcccagc aaaaaggcga gataagccca gacatcaaca
      841 cggcaatgac ttcacgttta ctgctggatc tgacctacgg tgtactggcc gatatcgaag
      901 cggaagatct ggcgcgtgaa gcgtcgtttg ctcagggatt acgcgcgatg attggcggta
      961 tattaaccgc atcctgatcc tctctctctt tccgcgggct ggtgacaact gagcccgcgt
     1021 ttcatatcgt aatttctctg tgcaaaaatc atcctcccag ggatcggaga attccaccta
     1081 aatattcatc gtagcaatat atcatgaggg tttatcgttc ccaatatgtt cgaatgaacg
     1141 ttcgattgct tattttgtgg cttctgtcaa cgctgtttta aagattaatg cgatcaatat
     1201 cacgctgtgg gtattgcagt ttttggtttt ttgatcgcgg tgtcagttct ttttatttcc
     1261 atttctcttc catgggtttc tcacagataa ctgtgtgcaa cacggaattg gttaactaat
     1321 cagattaaag gttgaccagt atttttatct taatgaggag tcccttatgt tacgtcctgt
     1381 agaaacccca acccgtgaaa tcaaaaaact cgacggcctg tgggcattca gtctggatcg
     1441 cgaaaactgt ggaattgatc agcattggtg ggaaagcgcg ttacaagaaa gccgggcaat
     1501 tgctgtgccg ggcagtttta acgatcagtt cgccgatgca gatattcgta attatgtggg
     1561 caacgtctgg tatcagcgcg aagtttttat accgaaaggt tgggcgggcc agcgtattgt
     1621 actgcgtttc gatgcggtca ctcattacgg caaagtgtgg gtaaataatc aggaagtgat
     1681 ggagcatcag ggcggctata cgccatttga agccgatgtc acaccgtatg ttattgccgg
     1741 gaaaagtgta cgtatcactg tttgtgtgaa caacgaactg aactggcaga ctatcccgcc
     1801 gggaatggtg attaccgacg aaaacggcaa gaaaaagcag tcttactttc atgatttctt
     1861 taactacgcc gggatccatc gcagcgtaat gctctacacc acgccgaaca cctgggtgga
     1921 cgatatcacc gtggtgacgc atgtcgcgca agactgtaac cacgcatctg ttgactggca
     1981 ggtggtggca aatggtgatg tcagcgttga actgcgtgat gcggatcaac aggtggttgc
     2041 aactggacaa ggcaccagcg ggactttgca agtagtgaat ccgcacctct ggcaaccggg
     2101 tgaaggttat ctctatgaac tgtgcgtcac agccaaaagc cagacagagt gtgatatcta
     2161 cctgctgcgc gtcggtatcc ggtcagtggc agtgaagggc gaacagttcc tgatcaacca
     2221 caaaccgttc tactttactg gctttggtcg tcatgaagat gcggatttgc gcggcaaagg
     2281 attcgataac gtgctgatgg tgcacgatca cgcactaatg gactggattg gggccaactc
     2341 ctaccgtacc tcgcattacc cttacgctga agagatgctc gactgggcag atgaacatgg
     2401 aatcgtggtg attgatgaaa ctgcagctgt cggctttaac ctctctttag gcattggttt
     2461 cgaagcgggc aacaagccga aagaactgta cagcgaagag gcagtcaacg gggaaaccca
     2521 gcaggcgcac ttacaggcga ttaaagagct gattgcgcgt gacaaaaacc acccaagcgt
     2581 ggtgatgtgg agtattgcca acgaaccgga tacccgtccg caaggtgcac gggaatattt
     2641 tgcgccactg gcggaagcaa cgcgtaaact cgacccgacg cgtccgatca cctgtgtcaa
     2701 tgtaatgttc tgcgacgctc acaccgatac catcagcgat ctctttgatg tgctgtgcct
     2761 gaaccgttat tacggttggt atgtccaaag cggcgatttg gaaacggcag agaaggtact
     2821 ggaaaaagaa cttctggcct ggcaggagaa actgcatcag ccgattatca tcaccgaata
     2881 cggtgtggat acgttagccg gcctgcactc aatgtacacc gacatgtgga gtgaagagta
     2941 tcagtgtgca tggctggata tgtatcaccg cgtctttgat cgcgtcagcg ctgtcgtcgg
     3001 tgagcaggta tggaatttcg ccgattttgc gacctcgcaa ggcatattgc gcgttggcgg
     3061 taacaagaaa gggatcttca ctcgcgaccg caaaccgaag tcggcggctt ttctgctgca
     3121 aaaacgctgg accggcatga acttcggtga aaaaccgcag cagggaggca aacaatgaat
     3181 caacaactct cctggcgcgc catcgtcggc tacagcctcg gtgacgtcgc caataacttc
     3241 gccttcgcaa tgggggcgct cttcctgttg agttactaca ccgacgtcgc tggcgtcggt
     3301 gccgctgcgg cgggcaccat gctgttactg gtgcgggtat tcgatgcctt cgccgatgtc
     3361 tttgccggac gagtggtgga cagtgtgaat acccgatggg gaaaattccg cccgttttta
     3421 ctcttcggta ctgcgccgtt aatgatcttc agcgtgctgg tattctgggt gccgaccgac
     3481 tggagccata gcagcaaagt tgtgtatgca tatttgacct acatgggact cgggctttgc
     3541 tacagcctgg tgaatattcc ttatggttca cttgctaccg cgatgaccca acaaccacaa
     3601 tcccgcgccc gtctgggcgc ggctcgcggg attgcgcttc attgaccttt gtctgcctgg
     3661 catttctgat aggaccgagc attaagaatt ccagcccgga agagatggtg tcggtatatc
     3721 atttctggac aattgtgctg gcgattgccg gaatggtgct ttacttcatc tgcttcaaat
     3781 cgacgcgtga gaatgtggta cgtatcgtgg cgcagccgtc attgaagatc agtctgcaaa
     3841 ccctgaaacg gaatcgcccg ctgtttatgt tgtgcatcgg tgcgctgtgt gtgctgattt
     3901 cgaccttcgc ggtcagcgcc tcgtcgttgt tctacgtgcg ctatgtgtta aatgataccg
     3961 ggctgttcac tgtgctggta ctggtgcaaa acctggtcgg tactgtggca tcggcaccgc
     4021 tggtgccggg gatggtcgcg aggatcggta aaaagaatac cttcctgatt ggcgctttgc
     4081 tgggaacctg cggttatctg ctgttcttct gggtttccgt ctggtcactg ccggtggcgt
     4141 tggttgcgtt ggccatcgca tcaattggcc agggcgttac catgaccgtg atgtgggcac
     4201 tggaagctga taccgtagaa tacggtgaat acctgaccgg cgtgcgaatt gaagggctca
     4261 cctattcact attctcattt acccgtaaat gcggtcaggc aatcggaggt tcaattcctg
     4321 cctttatttt gggattaagc ggatatatcg ccaatcaggc gcaaacgccg gaagttatta
     4381 cgggcatccg cacatcaatt gccttagtac cttgcggatt tatgctactg gcattcgtca
     4441 ttatctggtt ttatccgctc acggataaaa aattcaaaga aatcgttgtt gaaattgata
     4501 atcgtaaaaa agtgcagcag caattaatca acgatatcac tagttaatat tcaataaaaa
     4561 taatcagaac atcaaaggtg caactatgag aaaaatagtg gccatggccg ttatttgcct
     4621 gacggctgcc tctggcctta cctctgctta cgcggcacaa ctggctgacg atgaagcggg
     4681 actacgcatc agactgaaaa acgaattacg cagggctgat aagcccagtg ctggcacggg
     4741 aagagatatt tacgcatggg tacagggagg attgctcgat ttcaatagtg gttattattc
     4801 caataattat tggcgttgaa ggcggggcgt attatgttta taaattaggt gctcgtgctg
     4861 atatgagtac ccggtggtat cttgatggtg ataaaagttt tggctttgcc ctgggggcag
     4921 taaaaataaa acccagtgaa aatagcctgc taaaattagg tcgcttcggg acggattata
     4981 gttatggtag cttaccttat cgtattccgt taatggctgg cagttcgcaa cgtacattac
     5041 cgactgtttc tgaaggagca ttaggttatt gggctttaac gccaaatatt gatctgtggg
     5101 gaatgtggcg ttcacgagta tttttatgga ccgattcaac aaccggtatt cgtgatgaag
     5161 gtgtttataa cagccagacg ggaaaatacg ataaacatcg cgcacgttct tttttagccg
     5221 ccagttggca tgatgatacc agtcgctatt ctctgggggc atcggtacag aaagatgttt
     5281 ccaatcagat acaaagtatt ctcgagaaaa gcataccgct tgacccgaat tatacgttga
     5341 aaggggagtt gctcggcttt tacgcgcaac ttgaaggttt aagtcgtaat accagccagc
     5401 ccaatgaaac ggcgttggtt agtggacaat tgacctggaa tgcgccgtgg ggaagcgtat
     5461 ttggcagtgg tggttatttg cgccatgcaa tgaatggtgc cgtggtggat accgacattg
     5521 gctatccctt ttcattaagt cttgatcgta accgtgaagg aatgcagtcc tggcaattgg
     5581 gcgtcaacta tcgtttaact ccgcaattta cgctgacatt tgcaccgatt gtgacccgcg
     5641 gctatgaatc cagtaaacga gatgtgcgga ttgaaggagc gggtatctta gggggtatga
     5701 actatcgggt cagcgaaggg ccgttacaag ggatgaattt ctttcttgct gccgataaag
     5761 gacgggaaaa gcgcgatggc agtacgctgg gcgatcgcct gaattactgg gatgtgaaaa
     5821 tgagtattca gtatgacttt atgctgaagt aagaaaaaac gccggagaga aaaatctccg
     5881 gcgttttggc tgtgaattac tgctgcggaa tagcgggtac agccggaacg tttaatgtcg
     5941 gcatcgcaaa catacccacg aaatcttcca gtggcatttt ctgcccgttt aacgttatct
     6001 gaccgttagc atattgcagg ctggtggtga tggtattgtc ctgcaaggtg gtcagacgga
     6061 acatctgccc cattgctgat gcaccttcaa cttgctgttt cgccagtttt ttcgcttgat
     6121 cttcctgata accttccagc ttcgctacct gagtcatcaa ctcagttgcc atatccaccg
     6181 gaatggtcag tttcgcatcc agagatttaa ccgagcggtc cacttcctgc gccagcgttt
     6241 gcggcgcttc tttagtcgtt gccggatctt tcaggaacag cgacagattc agcgcacttt
     6301 caccctgact gtttttccag cttagcggcg cgatagtaat caccggatcg cctttcagca
     6361 tcagcggcag agcgctaaag aaggcttccg tcactttctc ctgataaagt tcgggattgt
     6421 tggcaatttc tggctgtgcc agcagcgcct gagtttgcgc gttatattgc tggctaaact
     6481 gatgccaggc ttcgccatca atttggccga cttttaaagt cagcttgcca ctgcccagat
     6541 cctgattctg taccttcagg ctgtttagcg agtaatccag ttggctattg atcgttttac
     6601 cgtcattgac cagatccgat ttaccgctga tctccatgcc ttccagcagt gccagttctt
     6661 tgccctccac tgaaatggtc attttttcca gcgacagttt ttggtttcct acgcgctcac
     6721 caaaacttgc cagcgtgctg gaaccgtcgg ttttcagatt attaaaggtt aactgcactt
     6781 tctggttgta ttcgttaacc gcgtctatcc gaccactttg cgcctccccg gaaagggaga
     6841 tagctttgcc gtctctgtct gcatttaact ggaactcgcc gccgctaaag gcgacttttt
     6901 catccttttg ctcgtaattc agtggcttga gcgaaatgtc ggaactggaa tctccgctgt
     6961 aaccaatgcg ggagttaatc tcaaaaggcg tttcaccttt tgccatatca aacagtggtt
     7021 tgcttacttc gttattaacc agcgtggttt gaattgatgc catcgacggg atcagattca
     7081 gttttttaag ctgggcaagc gggaagggac catgatcaac cgattcgttg aagatgacgc
     7141 tctgaccgct tttaatccac ggatttactt ttccggcaat gggtttcacc aacagttgca
     7201 actggctgct gaatacgccg cgatgatagt tttgataact gacttccagg ttggattcag
     7261 gagctgtcag tttgagttgc gcgttcgcct gcgcgaccat gtcttcgaga tgggtttcaa
     7321 tcttcttgcc tgtataccat gcgccgcctg tccagactac gcctagcgca acaatgacgc
     7381 ctaccgctac cagcgattta ttcataatga ttatccataa aatgaaatca ggcggactgg
     7441 ccgcctgaag gtgttataag cctttaataa gcttagcaag agatgttaat tttttcagta
     7501 agctcttaca gcttgttgta aacacgcgct aaacggccgt ggcctttgac agtcaccggt
     7561 gattcgttgg cggcaataaa cgctgattca cccggtttaa gctgtaactg ctgagaacct
     7621 ttacacagcg ttgcatcgcc ttcgacgcag aacaaaatgg cggcactctg ctggctgatg
     7681 gtggtttctt tatcactaag gtcatgcaac gagaaggcaa aatcatccac aggaatcggg
     7741 aagtccagtt ctgcaccttg tttcaccggc tgggtcaaca acttgttagc cggtttggct
     7801 tcgaacttca cgttggcaac cagttccgga atatcaatgt atttaggcgt cagacctgca
     7861 cgcagcacgt tatcggagtt cgccatcact tccagcgcca cgccttgcag gtaagcgtgc
     7921 ggtgtttcag cgaacaggaa catcgcttcg ccaggattca atttcaccac attcagcaac
     7981 agcggggaga acaggccgct gtcttccggg taaaattcag aaattaaacg aatcgtttgc
     8041 catggttcac cctgctggct gtcgagggcc gattttaaaa tcgccagcgc gcgggatttt
     8101 tcttcaccct gcatattcaa caggctggcg aacagttcgc ttaaacgttc ggcatcaggc
     8161 tgttgtaaaa agtgagcaat cgccggatgt gcacctgcga ccggctggag cagggagaca
     8221 atctcggaaa actcacgaaa cgcgttcatc gcgaggaaag gggtcagggc gaaaaccagc
     8281 tcaggcttgt gattaggatc tttatagtta cgctcagcgg catccatcgg aatacctgca
     8341 gcattttctt tggcaaaacc gatttcagaa ttgcgtttgt ttggatgaac ctgaatggag
     8401 agcggctggg ctgcgcataa tactttgaac aggaaaggca actcgccaaa gcgtttggca
     8461 acggcatctc ccaaaagagt cgctttatca ctctcaatca catcacgcag tgaaacgata
     8521 tctcctgcgg catcgtgcac acgtgaactg ctctttggat gcgcgcccat ccacaactcg
     8581 gccatcggct ggctggacgg attttccata ccataaagtt cagtcaacgc cgttttgctg
     8641 ccccaggcat agttttgcac tgagttaatg agtttttgca tgatcaatcc ctgttttaat
     8701 gtggaaatta atcccgctat taaagcaaga atcctacggg aagtaacctg gagccgcaaa
     8761 aagtcgtact agtctcagtt tttgttaaaa aagtgtgtag gatattgtta ctcgctttta
     8821 acagggcaac ggaacacccg cccagagcat aaccaaacca ggcagtaagt gagagaacaa
     8881 tgtcaaacaa accctttcat tatcaggctc cttttccact caaaaaagat gatactgagt
     8941 attacctgct aaccagcgaa cacgttagcg tatctgaatt tgaagggcag gagattttga
     9001 aagtcgcacc cgaagcgtta actctgttgg cgcgtcaggc gtttcatgat gcgtcattta
     9061 tgctgcgtcc ggctcaccaa caacaggtgg ccgacattct gtgtgacccg gaggccagcg
     9121 aaaatgataa atatgtggcg ctgcaattcc tgcgtaactc cgacatcgcg gcaaaaggcg
     9181 ttctgccaac ctgtcaggat accggcaccg cgattattgt tggtaaaaaa gggcagcgtg
     9241 tatggaccgg tggcggtgat gaagcagcgc tggcgcgcgg tgtttataac acttatatcg
     9301 aggataatct gcgctactcg caaaacgcgc cgctggatat gtataaagag gtgaataccg
     9361 gcaccaactt gccagcgcag atcgatcttt atgccgttga tggcgacgag tacaaattcc
     9421 tctgtatcgc caaaggtggc ggttcggcaa acaagacgta tctctatcag gaaaccaaag
     9481 cgttactgac gccgggaaaa ctgaaaaatt acctggttga gaagatgcgc acgctgggta
     9541 cggcggcctg tcctccgtat catattgcgt tcgttattgg tggaacttct gcagaaacga
     9601 atcttaaaac ggtgaaactg gcttccgcta aatactatga tgaactgcca acggaaggga
     9661 atgagcacgg tcaggcgttc cgcgatgtgg aactggaaaa agaattgctg atcgaagcgc
     9721 aaaatcttgg tctgggtgcg cagtttggtg gtaaatactt cgctcatgac atccgcgtga
     9781 ttcgcctgcc acgtcacggc gcatcctgcc cggtcggtat gggcgtctcc tgttctgctg
     9841 accgtaatat caaagcgaag atcaaccgtc aggggatctg gatcgaaaaa ctggaacata
     9901 atccaggcaa atatatcccg gaagagctgc gcaaagcagg agaaggcgaa gcggtgcgcg
     9961 ttgacctcaa ccgtccgatg aaagagatcc tcgcacagtt gtcgcagtat cccgtttcta
    10021 cacgcttatc gcttaacggc acgattatcg tcggtcgtga tattgctcac gccaaactga
    10081 aagagcggat ggataacggt gaagggctgc cgcagtatat taaagatcat ccgatttact
    10141 acgcgggtcc ggccaaaacg ccggaaggtt atgcctccgg ttctcttggc ccaacgaccg
    10201 ccggacggat ggattcttat gtcgatcaac tgcaagcgca gggcggaagt atgatcatgc
    10261 tggcgaaagg caaccgcagc cagcaggtga cggatgcctg taaaaaacac ggcggcttct
    10321 acctcggcag tatcggtggt ccggcagctg tattggcgca gggaagtatt aagagcctgg
    10381 aatgtgttga atatccggaa ctgggaatgg aagccatctg gaaaattgaa gtggaagatt
    10441 tcccggcgtt tatccttgtg gatgataaag gaaatgactt cttccagcag atacaactca
    10501 cacaatgcac ccgttgtgtg aaataaacag agccgccctt cggggcggtt tttttacatg
    10561 gcacgaaaga ccaaacgttt gttatcaaat ggtaaataat gagtgagcta aaagttgctt
    10621 aacgaaagca aaacagaaag aaaaaattaa tcaggtgagg agcaggccat gaatacagta
    10681 cgcagcgaaa aagattcgat gggagcgatt gatgtcccgg cagataagct gtggggcgca
    10741 caaactcagc gctcgctgga gcatttccgc atttcgacgg agaaaatgcc cacctcactg
    10801 attcatgcgc tggcgctaac caagcgcgca gcggcaaaag ttaatgaaga tttaggcttg
    10861 ttgtctgaag agaaagcgag cgccattcgg caggcggcgg atgaagtact ggcaggacag
    10921 catgacgacg aattcccgct ggctatctgg cagaccggct ccggcacgca aagtaacatg
    10981 aatatgaacg aagtgctggc taaccgggcc agtgaattac tcggtggcgt gcgcgggatg
    11041 gaacgtaaag ttcaccctaa cgacgacgtg aacaaaagcc aaagttccaa cgatgtcttt
    11101 ccgacggcga tgcacgttgc ggcactactg gcgctgcgca agcaactcat tccacaactt
    11161 aaaaccctga cccagacgct gagtgaaaaa tcccgcgcat ttgctgatat cgtcaaaatc
    11221 ggtcgtaccc acttgcagga cgccacgccg ttaacgctgg ggcaggagat ttccggctgg
    11281 gtagcgatgc tggagcataa tctcaaacat atcgaataca gcctgcctca cgtagcggaa
    11341 ctggctctgg gcggtacagc ggtgggtact ggactaaata cccatccgga atatgcgcgt
    11401 cgcgtagcag atgaactggc agtcattacc tgtgcaccgt ttgttaccgc accgaacaaa
    11461 tttgaagcgc tggcgacctg tgatgccctg gttcaggcgc acggcgcgtt gaaagggttg
    11521 gctgcgtcac tgatgaaaat tgccaatgat gtccgctggc tggcctctgg cccgcgctgc
    11581 ggaattggtg aaatctcaat cccggaaaat gagccgggca gctcaatcat gccagggaaa
    11641 gtgaacccaa cacagtgtga agcattaacc atgctctgct gtcaggtgat ggggaatgac
    11701 gtggcgatca acatgggtgg cgcttccggt aactttgaac tgaacgtctt ccgtccgatg
    11761 gtgatccata atttcctgca atcggtgcgc ttgctggcag atggcatgga aagtttcaac
    11821 aaacactgcg cagtgggcat tgaaccgaat cgtgagcgaa tcaatcaatt actcaatgaa
    11881 tcgctgatgc tggtgactgc gcttaacacc cacattggtt atgacaaagc cgccgagatc
    11941 gccaaaaagg cgcataaaga agggctgacc ttaaaagcgg cggcccttgc gctggggtat
    12001 cttagcgaag ccgagtttga ccgctgggta cggccagaac agatggtcgg cagtatgaaa
    12061 gccgggggtt aatctgcaac atacaggtgc agccgtggaa tgattaaacg aagcggctgc
    12121 gcctgtggtt tataacggtg ctgcacattg tcggcatcgt aatttaacaa ctcaccaacg
    12181 tccggcacgc ccgcgccatt atcccgatta atcagcgcaa tcagcggcgt agggcaggcg
    12241 tgttgtactt gtttttgatc tcccttatac cagacgcggg caatcggctg caccttcacc
    12301 ggacgtttga tttttaactt cgcgttctgt ggcagggcag cgatatcctg atattctcgc
    12361 tccagttttc tttgccactc ctcgcgcgtc cacggtgcga cactgcgtgg tgatttcagg
    12421 cttttttcca gctgtgccag gacttcatca cgatgcaaat ttttaatgat atgtttatta
    12481 gcccagccaa aacgtaaagt ggcggggtcg tgcagaacgg tgagcgtgcg gtaagcatta
    12541 agggtaatca gccccggaaa atgacgatgt acccattcaa aacgtgccac ggaggggagt
    12601 tctgattcaa ccgtgacgat atgctcgaac gtggtcttga gtttattgat gtgctgaata
    12661 tgactgacca acgctgcttg cgaaaagtta tcgacctggt aacacaacac gccaggcaga
    12721 cggacggcgg ctttgctgct gcgattttcg gactgttgtt gaataaataa atggcggaaa
    12781 tgacgcaacg ccagcgactg cgcgtcgttg ccgagatgtt gttttacctc aatacgatta
    12841 agcggattat gctcatcctc tttttttacc tccggcaaag agaacacgcg ggcaaccaat
    12901 agcttgtgtt gctcaagatg agcggcaaat gcagccagct cttgttccat ctggcgaaaa
    12961 gtagtgttga gtcggtctac gagatcgtaa cgcgccataa tattaatcac tttagttaca
    13021 acatccttat tttatagcac agtggtggtg acttgaccac cgtgcgcata gtgtcaggca
    13081 gaggtaaatt gcgggatgtt atgccataac ggccagctga acgagaagcg ggcacccccc
    13141 agttcgctgg tgtcacaatt aaccgtaccg cccattgcca gtgctataga gtggacaatg
    13201 gccagcccca gcccgcagcc gccggttgag cgatcccggc tgggatcgag gcgaacaaaa
    13261 ggttcaaaga tatgttcgcg gttttctggg gcaatccctg ggccatcatc ctcaacaatt
    13321 aatgtcgctc tattccccga cagtagcagg ctggtttcaa ccgttgagtg acagtagcgc
    13381 agggcgttat tgagcaaatt atccagcacg cgctccatta agcgcatatc caacgcagca
    13441 taatggcctt gcgcgagcgt ttttatccgt accgttttat cgggcgttac tgcctgaata
    13501 tctgccagat gcgttgacag ccacaacggc aggtctggtt cgctaagatg aagctcattt
    13561 tgtgggcgat cgagccgggc ataagtcagc agctcttcaa ttaaagcttc aagttgactg
    13621 atatcgcgat tcaacgcctg ggattcggcg gcgctcaggt tatcgctcat ctccagtcga
    13681 taacgcaggc gcactaacgg tgttcgcagt tcgtgagcga taccgtcaat aagctgtttt
    13741 ttgctggcaa tcaaggcgtt gatattgtcc gccatctggt taaatgcgac gccaagtcgt
    13801 tcaaagctcg aaccttcatc aaagtggata cgctcactga gatgcccatc gccaaatcgt
    13861 tgcgccgctg cttccagttt taacatatcc tgccagtgcg gacgcatcca gataaacacc
    13921 ggaaaggcga gggaaatggc aataaaagcg atcagggcga tatccagcaa tcgcatctga
    13981 tggaggtaat aaagataagg aacaggacca actgccagca cgtagtggct gcgtgggata
    14041 cgttgcaaaa aagtgtactg atcgtccaga gcgacaattt cgccgccacg cagccggtgc
    14101 atggaaatat catcaagatg atatttactc agcggctcga cacgcagatc gaaagagaga
    14161 tttaaatcca tctctttcag cgtcttaccc cagtcgtgtg gggggatctc acgcaattcg
    14221 ctgcgcatca gatacagcga actgttcatc aaatcatcca gcgactgttt gcctgcgcgt
    14281 tcggcggtaa atttgtacac cagcccgacc agcagagaca tcacaaggaa gcagacaaac
    14341 aataacaggt aaaactggat aaacagtttt ttcatcgctt attcccacgc atgaggcgca
    14401 aaaagatagc ctttgttacg cacggtttta atacgataag gttctgcggc gttatcgagc
    14461 agtttttttc ttaaccgcga aatagccacg tccacgctac gatccagccc gtcataactg
    14521 acgccgcgta aatttttcag caatgcatcg cggtccatga tttgcccggc atgggtagct
    14581 aattcccaca ataattcgaa atcagctgtc gagagcgaga tttcagtgtt agccagggag
    14641 actacgcggt tgatgggatc gatggtcaac gtgccgaaat gcagggcttt gtagggagtc
    14701 agagacgttt cctgaatacc tttggtcact gtggcttgct cattctgacg caaatgcaag
    14761 cgtaaacgcg ctaacaaaac agcagggggc gtcgttttga gaatatagtc gcaggcgccc
    14821 atttccagtg ccaggatgtg gttcatatcg ctatcgagag aggttagaag aacaatcggt
    14881 ccggaccact ttgcgcgtaa atcacgacaa atggtcatgc cgtccttgcc tggtagcatg
    14941 atgtcgagta acaccaaatc cggattttct cgcagaatag tttcttcggc ccggtcgccg
    15001 cgcggctcta cggtaacctg catatcatgt tttgccaggt atgcggcaat cagtgcaccg
    15061 acttccgcat catcttccac aaatacgata gtgttcataa cattcacggt agatataaaa
    15121 acgtcacaat acaccgcact gtttttactt actatcaatc gtttctaaac aaggtttcat
    15181 caggtattct actgatgact tgttatggaa gtgttaaggt aaaaagatgg ggctggtaat
    15241 caaagccgcg ctcggtgcgc tggtagtgct gttgattggt gttttagcaa aaacgaaaaa
    15301 ttattatatc gccgggctga ttccactttt cccgaccttt gcgcttatcg cgcattatat
    15361 tgttgccagc gaacgcggca ttgaagcctt acgcgcaacc atcattttta gtatgtggtc
    15421 gattattccc tattttgttt acctggcgtc gctatggtat ttcaccggaa tgatgcgctt
    15481 gcccgctgct tttgttggct ctgttgcgtg ctggggaata agcgcatggg tgttgattat
    15541 atgctggatt aagctgcatt aacgcagatg acgaccgcca tcaagtggga gactgcgtcc
    15601 ggtgacaaag cagctggtaa gtaagtaatc gaccaggtcg atcacttctt tctcgccagg
    15661 cgcggttttc atcagtgatt tattcagcgc ctgttgtcga tattcggcat catcatgttc
    15721 attaaacagg atcagcgatg gcgcaataga attcactttc acttccggtg ccagcttgcg
    15781 ggcaaacgag cgggtcatat tatccagtgc cgctttgctt gcagcatagg caatatgttt
    15841 gtcgctaccg cgctccacca cataatcggt aaagtgaatg atatcgctgg cggcgtgtcc
    15901 gtgcccacgc agtaatcttt ccagagcatg gttgagcagg tatggggtat taacgtggat
    15961 ctgcatcatg caagccagta cgtcggtcag tggcgctccc ggtttttccg ccatccacgc
    16021 gctggcgtta tgcaaaatag cacgcagacc atgggtgctt tttagtactt catcggcaaa
    16081 cgccatcaca ccgtcgttgg tcgaaaaatc agcctgaata cactgcgcac ctgccttaat
    16141 cagtccatca atggcgggat agtgcgtccg atagctgaca atcaccggtt gcttttgatt
    16201 aatgaaatgc catgcgaggg cgaggccgat gcggcgacct ccgccagtaa ttaatattgg
    16261 caaggactgg gttttaccca tcgttatctc ctttgctatc caacgatggg atgaacgtta
    16321 tcccaccagc atccaggtcg ccggaactga ggcaattaac agcatgccaa tcagcaccat
    16381 ttcctgacgg ttcagtacat tatcatgtgt atgcgtttta cgcgcgtaca ggaaaaccag
    16441 cagccccggc gcatacagaa caacggataa cagcaagtgc attggaccag aggcgtacag
    16501 taaccataag ccataaatgc aggcaccgac acctaccgcc ttatgcagtg gacgggttgc
    16561 gattttcagc aagaacgcgc cgaccaggaa atagggcacc agaatcattt ctgaggcgat
    16621 ggtcagcaat gtgttgtaat cggaaccggt cagccagatg agcaccagac aaatttgcac
    16681 gcagatgttg gtcagccaca gtgaagcgga tggcgcagct tgtgcgttct ggcgcgcaaa
    16741 aatgcgcggg aatgctttat gagtggctgc aaggaacgga acttctgctg ccatgatggt
    16801 ccagcttaag tacgcgccgc aaacggaaac gatcaaaccg gcagcgatga tgatttcgcc
    16861 ccacggtccc atcatttcca ccatcagacc ggccattgac gggttacgaa tttcagccag
    16921 ttcaggacgt gccaccacgc ccagcgaaag cagcgttacc agcaaataaa cgcccagagc
    16981 ggagagaacc gccagcagtg tcgctttgcc aacatcacgc ttattacgcg cacgcgcaga
    17041 aacaaccacg gcaccttcca caccaatgaa aacccacagg gtgatcagca tggtgttttt
    17101 cacctgttcc cacacgggta cgccaagtgc aagtccggtg aagtcgagct tgaaggtatc
    17161 cagtttgaac atcatcatcg ccagcacaac aaacagaccc aacggcaaca attttgccag
    17221 tgtcgccaca aggttaatgc tggcagcggt ttgcaccccg cgcaggatca aaaagtgaac
    17281 aatccacaat aaagccgatg caccgacgat cgattgccag gtattaccat cgccaaacag
    17341 gcgcaattcc ggcgtgtccg taaaaaagct taacgcggaa aaaacgatca ccagatagga
    17401 gacgttggcg atgaccgcgc acagccagta tccccatgcg gaacaaaagc cgattagctc
    17461 gccaaaccct tcgcgggcat aggtaaagat accgccgtca agttcggggc gaatgcgcgt
    17521 gaggatcagc atggcaaagg ccagcaataa aatgccagcg ccagtaatac cccagccgat
    17581 gagcagtgct gccgggctgg caactgccgc catattttgc ggcagactga aaacacccgc
    17641 gcccagcatt gagcttaata ccagcgcggt gagtgcgctc agtcccagtt tcttttccat
    17701 cgatatccag tgattaaaac gtgacaagaa gaataaatat tagggcaaaa cgcataaaaa
    17761 tggagtttgc cactgaagcg cgggatttta cgaagagatg tgtctgcatg caatggtcgc
    17821 agggaaattt atgactaaaa atgcgaaagg cggcatcaag ccgccttata ggagtaactg
    17881 aatagttatt tatacagatc tgcgctgacg gtcaggttat taccacgttc ctgccactgg
    17941 cgggtgatgt ggtaatactt agcacctttc ttcgcggcac gtttcgcaac ctgataggag
    18001 acttcggtca tgttgccgta gttgccagag aatttgatgc tgtcgaacgg gaccatcatc
    18061 gctgctgtcg ctttgttcag ttcttcgact ttagtgccat ccgggagcgt gacggtgtaa
    18121 cgcccgcctt ttgatgactg ggtttcaaag aagcgaccga cttcagaact tggtgatgcg
    18181 gtagtcgcaa cacccgggat ctcaactttc ttcgcggctt cgccaccggc agccagagct
    18241 gcacgtcctg cttcggaatc tgccgggatt acatccgggc tctggacgat acgtttctta
    18301 gcatcttttt tatagatgaa tgcagtaata cgctggttac cgccctggtt ggcatcgatt
    18361 tgacgaacaa tgtagaaaga gtaggcacct ttcgcttttg ccgctttggt gatggcatca
    18421 ttgacttctg gctggctacg atagaagccc tggacggtga ccgtgtcaaa cggttcaatc
    18481 agaacagcct gatctttcgg cagttcgaca acaccgttaa ttacgcgatt acttgtttct
    18541 tctgcttttt cagcatcggc tttatagagg tcagcgacca cacgccagtt accgctgtta
    18601 ccaaaatcag aagtgtcgac aacataaaaa gaggcggcac cttctttatc tgcgcgacga
    18661 gaaacggctt tcaccgcttc gccaatagca ttaaaacgac cggtaaccac tacacggtca
    18721 aaaggtttaa ccgctgccgc ttgctccggt gtcagttctg ttgctgcgtt aacggagaat
    18781 gccgtagcag aaagcagtgc cgacgccagg agggtgttct taagcttcat aaaaataatc
    18841 cttcgccttg cgcaaaccag gtactggtat tgttattaac gagaaacgtg gctgattatt
    18901 gcatttaaac ggtgtaactg tctgcgtcat ttttcatatc acattcctta aaccaatttt
    18961 aattctgctc aaatgaccgt ctatgcttaa aaaacagccg tatcaccatc aatactactg
    19021 aagcaactga attgtataag ttaatttaat gttaagtagt gatttgtgcc ggggcgatgt
    19081 ctcgttttac ccggccgccg aagacaatta tcagtcttta tccggcgttc taaggtgttt
    19141 atcccactat cacggctgaa tcgttaatat tttgcgagtt cacgccgaaa tactgatttt
    19201 tggcgctaga tcacaggcat aattttcagt acgttatagg gcgtttgtta ctaatttatt
    19261 ttaacggagt aacatttagc tcgtacatga gcggcttgtg tggctcctga cacaagcaaa
    19321 ccatcatcaa taaaaccgat ggaagggaat atcatgcgaa ttggaatacc aagagaacgg
    19381 ttaaccaatg aaacccgtgt tgcagcaacg ccaaaaacag tggaacagct gctgaaactg
    19441 ggttttaccg tcgcggtaga gagcggcgcg ggtcaactgg caagttttga cgataaggcg
    19501 tttgtgcaag cgggcgctga aattgtagaa gggaatagcg tctggcagtc agagatcatt
    19561 ctgaaggtca atgcgccgtt agatgatgaa attgcgttac tgaatcctgg gacaacgctg
    19621 gtgagtttta tctggcctgc gcagaatccg gaattaatgc aaaaacttgc ggaacgtaac
    19681 gtgaccgtga tggcgatgga ctctgtgccg cgtatctcac gcgcacaatc gctggacgca
    19741 ctaagctcga tggcgaatat cgccggttat cgcgccattg ttgaagcggc acatgaattt
    19801 gggcgcttct ttaccggaca aatcactgcg gccgggaaag tgccaccggc aaaagtgatg
    19861 gtgattggtg ccggtgtcgc aggtctggcc gccattggcg cagcaaacag tctcggcgcg
    19921 attgtgcgtg cattcgacac ccgcccggaa gtgaaagaac aagttcaaag tatgggcgca
    19981 gaattcctcg agctggattt taaagaggaa gcgggcagcg gcgatggcta tgccaaagtg
    20041 atgtcggacg cgttcatcaa agcggaaatg gaactctttg ccgcccaggc aaaagaggtc
    20101 gatatcattg tcaccaccgc gcttattcca ggcaaaccag cgccgaagct aattacccgt
    20161 gaaatggttg actccatgaa ggcgggcagt gtgattgtcg acctggcagc ccaaaacggc
    20221 ggcaactgtg aatacaccgt gccgggtgaa atcttcacta cggaaaatgg tgtcaaagta
    20281 attggttaca ccgatcttcc gggccgtctg ccgacgcaat cctcacagct ttacggcact
    20341 aacctcgtta atctgctgaa actgttgtgc aaagagaaag acggcaacat cactgtggat
    20401 tttgatgatg tggtgattcg tggcgtgact gtgatccgtg cgggcgaaat tacctggccg
    20461 gcaccgccga ttcaggtatc agctcagccg cagacggcac aaaaagcggc accggaagtg
    20521 aaaactgagg aaaaatgtgc ctgctcaccg tggcgtaaat acgcgttgat ggcgttggca
    20581 atcatccttt tcggctggat ggcaagcgtt gcgccaaaag agttccttgg acacttcact
    20641 gtgttcgcgc tggcctgcgt tgtcggttat tacgtggtgt ggaatgtatc gcacgcgctg
    20701 catacaccgt tgatgtcggt caccaacgcg atttcaggga ttattgttgt cggagcactg
    20761 ttgcagattg gccagggcgg ctgggttagc ttccttagtt ttatcgcggt gcttatagcc
    20821 agcattaata ttttcggtgg cttcaccgtg actcagcgca tgctgaaaat gttccgcaaa
    20881 aattaagggg taacatatgt ctggaggatt agttacagct gcatacattg ttgccgcgat
    20941 cctgtttatc ttcagtctgg ccgggctttc gaaacatgaa acgtctcgcc agggtaacaa
    21001 tttcggtatc gccggtatgg cgattgcgtt aatcgcaacc atttttggac cggatacggg
    21061 taatgttggc tggatcttgc tggcgatggt tattggtggg gcaattggta tccgtctggc
    21121 gaagaaagtt gaaatgaccg aaatgccaga actggtggcg atcctgcata gcttcgtggg
    21181 tctggcggca gtgctggttg gttttaacag ctatctgcat catgacgcgg gaatggcacc
    21241 gattctggtc aatattcacc tgacggaagt gttcctcggt atcttcatcg gggcggtaac
    21301 gtttacgggt tcggtggtgg cgttcggcaa actgtgtggc aagatttcgt ctaaaccgtt
    21361 gatgctgcca aaccgtcaca aaatgaacct ggcggctctg atcgtttcct tcctgctgct
    21421 gattgtattt gttcgcacgg atagcgtcgg cctgcaagtg ctggcattgc tgataatgac
    21481 cgccattgcg ctggtattcg gctggcattt agtcgcctcc atcggtggtg cagatatgcc
    21541 agtggtggtg tcgatgctga actcgtactc cggctgggcg gctgcggctg cgggctttat
    21601 gctcagcaac gacctgctga ttgtgaccgg tgcgctggtc ggttcttcgg gggctatcct
    21661 ttcttacatt atgtgtaagg cgatgaaccg ttcctttatc agcgttattg cgggcggttt
    21721 cggcaccgac ggctcttcta ctggtgatga tcaggaagtg ggcgagcacc gcgaaatcac
    21781 cgcagaagag acagcggaac tgctgaaaaa ttcccattca gtgatcatta ctccggggta
    21841 cggcatggca gttgcgcagg cgcaatatcc tgtcgctgaa attactgaga aattgcgcgc
    21901 tcgtggtatt aacgtgcgtt tcggtatcca cccggttgcg gggcgtttgc ctggacatat
    21961 gaacgtattg ctggctgaag caaaagtacc gtatgacatc gtgctggaaa tggacgagat
    22021 caacgatgac tttgctgata ccgataccgt actggtgatt ggtgctaacg atacggttaa
    22081 cccggcggcg caggatgatc cgaagagtcc gattgctggt atgcctgtgc tggaagtgtg
    22141 gaaagcgcag aacgtgattg tctttaaacg ttcgatgaac actggctatg ctggtgtgca
    22201 aaacccgctg ttcttcaagg aaaacaccca catgctgttt ggtgacgcca aagccagcgt
    22261 ggatgcaatc ctgaaagctc tgtaaccctg acggcctctg cggaggccgt cactctttat
    22321 tgagatcgct taacagaacg gcgatgcttt gacctcccgc tgtttgttca agcgcaattt
    22381 tgacaataat tgtcaacggc acggaaagca gcatacccac cggtcctaac aaccatcccc
    22441 aaaaaatcaa cgacaaaaat accaccaatg tggaaagccc cagcccacgc cccatgatgc
    22501 gcggctccag aatattgccg aagacaagat taatcagcag atatcccgcc agcaccagca
    22561 acgcttcgta gaagccatta aacaccagta cctgagcgat aggggggatt gccgcgagaa
    22621 ctgaaccaat attggggatg taattaagcg caaaggccag caatccccag acaaaagcga
    22681 agcgaacatc gagtgcggcg agcatcgccc aggcgaccag gccggtgatg atgctgatgg
    22741 ctgttttcag caccagataa tgagacacgc tgtcaatcgc gcgctgaatc gccgccatcc
    22801 cttcaaccgg acgcgccatc atttgctgaa attttccggg caattgtggc acttcgagca
    22861 acataaacag caccgtcagc agcaataaaa agattgatga catggcatta gataactgcg
    22921 tcaataagtt ggtgagcaac gtcatcgccg cgttcggatc aatgtaatgc gccagttggt
    22981 caactgagac atcaatccct acgcgttgca acaacggttc aatcgcttgc agcggcgtca
    23041 taatagagtt gcgatattgc ggtaacgtcc gcgtcaactc attgagcgcg gaccccagat
    23101 aagctaacag caacaccatc gccatcacga tgatggtcat caaaatcgac actgccagta
    23161 cacgcggcac acgccagcgg accatgtgtt gcaccagcgg gttaagaata acagcaataa
    23221 ataatgcgag aataaacggc acgataatct cggcggcaaa acggataccg cagagaataa
    23281 tgaccagcat tcccaacata atgacgattt ttaggccatt gagcgtgatg atcggctttg
    23341 ccatgcttgt ccccgttttt tcttcctttg ctaataataa tgtctttttc gctccttcat
    23401 cataacgaaa atcaaaccgc tcaggtaaag aagtgaaaat attttgagtt aattcttaag
    23461 ctatgataca aatcaggcgt gttcaactac cgaggacaat tatcatccgc gatgacgaga
    23521 agcaacactg cggataattg taatattatg gacaatttgt tcaggacgtt attttctaca
    23581 tttacccatc ttcgtacctc atccactatc ttgctcgtag gtgagcagca ctggcgcaac
    23641 gcgctttagt cctttcttct gcctaagctt gcgctatgcg cggggcttga tcactttact
    23701 ttggtttcgc tgaattaagc gaaaattaaa ataattctct tgcaggagaa ggacaatgta
    23761 tatttattgg attttattag gcctggctat tgctacggaa attaccggta cgctgtcaat
    23821 gaaatgggcg agcgtcagtg agggaaatgg cggctttatt ttaatgctgg tgatgatttc
    23881 tctgtcgtat atatttctct ctttcgccgt taaaaaaatc gccttaggcg tagcttatgc
    23941 gctgtgggaa ggtattggta ttttatttat taccttgttt agcgttttgt tattcgacga
    24001 aagtttatcg ctgatgaaaa ttgccgggtt aaccaccctg gtggccggga ttgtgttgat
    24061 caagtcaggt acccgtaaag cgcgtaaacc tgaactggag gtgaaccatg gcgcagtttg
    24121 aatgggttca cgccgcctgg ctggcattgg caatcgtgct ggaaatcgtt gctaacgtct
    24181 ttttgaaatt ttctgacggc tttcgtcgca aaatatttgg cttgctctct ctggcggcgg
    24241 tgctggctgc ctttagtgcg ctttctcagg ccgttaaagg gatcgacttg tctgtcgctt
    24301 atgcattgtg gggcgggttt ggtattgccg ccacgttagc cgcaggttgg atcttgtttg
    24361 gtcaacggtt aaatcgtaaa ggctggattg gcctggtgct gctgttggct ggaatgatca
    24421 tggtgaaact tgcctgatga acacgctgcc cgcgctgtcg ggcagcgttt gaacattatt
    24481 tttgcgacag ttgatccagc ttgtcgcgaa aaccggtaac agaaatggcc cggttatcgg
    24541 cgcgccagcg atctttcgcg gcaggagccg agctttgcac cccaattaat tgccagccgt
    24601 catcggtatg caacatcaga ggcgaaccgc tgtcacccgg caaggtatcg cactgatgcg
    24661 acatcaccga cgtttgcgcc cagccagtca cttcacagtt ttgatgactg tacaacgtat
    24721 cgagatgatc ttcagggtag cccgcctgag tcactttacg accagccgct tttaatgcgg
    24781 cggtaagcgc ggctttatct ccctcaaata acggcaacgg tgtaatgcca gaagggggat
    24841 tacgtagcac aatcaaaccg aagtcccacg gcgcagctgc gggaggtaca atccagccat
    24901 ccccatctgc ttttaaccgc tttcccagtg ttggatcaac gcggccttct atgtcgtgga
    24961 tctcatagcg ccaaagacct ttatttgaca cgaaacgcag cgctaccgct ttatcggctt
    25021 taccctttgg cggcgtcaat aaacagtgtc ctgccgttaa tgccagattg ggtgcaatca
    25081 gcgtcgccgt acataaattg ccgctggccg tttccagttg gccaaccgca tcccacggtg
    25141 attgggtcgt gtcattcact ggcacacgat catcatgacc aaaaaacagg gtgctgacct
    25201 catcgtttgc cgatttggca acgtctggtt tatctgcaaa cacaaaagca gacgtcaaac
    25261 taattgcacc caacactaca gcaatggttg tacgcatatc acactctggt gggtaattat
    25321 gattattaaa agcaaaccct cataaatact atagacggga cgggatgaaa gtgggagtaa
    25381 aatcagataa ctacgatcag gaaagataaa aacgggcggc aatcagtgcg cataaaataa
    25441 ggatgataag aatgaactca aagcgataac ggcccaccat actaccctcc gctaaaggcg
    25501 gtgctaaacg ttacccgctt agcaccgtaa ttttcaggcg cgagggggcg cgccagcatt
    25561 actgttgaaa acttacgctg cgggttgtgc agcaggtttt gccggttgct gatggctgtg
    25621 tttcttggcg tgtttcttcg ctgcctgcgc tttttgttca ggagctttct gttcagcttt
    25681 ggcattttta tgatgctttt tagccgcctg cgctttctgg gcaggtgctg ctttatgctg
    25741 ttttttatga tgtgtggttt tcgcaggcgc tgctttggtg gtcgtcgcag tcggagcagg
    25801 tgtggtcgca gtctctgcag caaaggcagc agaagacaga cccatagcag cggcaacaac
    25861 cagagctaat acttttttca ttgtcatacc ctcaatttgt tttttcattt aaccccactg
    25921 cggggccgtt gaaataacta tatccctggg aatggcagac ttccgtgagt ggttggtttc
    25981 agcgtgtaac gatatgtaca aacgctgaat aaattacagc attgataata acgtattgtg
    26041 acttaaggaa aatttagcta ccaataaagt agtcttgatc gtgttaacta ttttactact
    26101 tacaaagcgg tagaataact gcgcatcagt aataaatgac acacagcaaa atgaatccgt
    26161 ttatttgggt acttataatc ctgatgacgc tagatgcgct gcgggaattg gctggcgctt
    26221 cgtctatttt aggatggcta ttaacgttgg tttgagcagg caataagtcc ggacgggtat
    26281 ttacctcagt ccggacttat tttttcaggc gtgcagacga tgatgcaaac gcgtcccgac
    26341 cagcagagca atgaccagca tcagagcaat aaatgcgccg acgccgttcc agccatagtt
    26401 atgccagaaa acaccaccca gcgtcccggc aatactcgac cccagatagt aactgaacag
    26461 atacagcgag gaggcctggc ctttagcgcg ttttgcgcgg gggccgatcc agctgctggc
    26521 aacggagtgg gctgcgaaga atccggctga gaagagtaac attccggcaa agatcagcca
    26581 cagcgagctg aataaggtca tcagtaaacc aaacagcata acccccgtcg aaaacaacat
    26641 caccggaccg cgtccatagc gggcggtcat ggttccggct ttgggtgagc tccatgtacc
    26701 ggtcaaataa gccagcgata ataagccaac cacggcctga ctgacatgcc agggggaaag
    26761 catcaaccta tagccgatgt aattaaacag cgtgacgaac gaccccatca gcaaaaagcc
    26821 ttctgcgaac aataacggta atccccggtc acgccagtgc agacgaaagt tgataaataa
    26881 cgtcttaggg cgcagcgaag tcgggcgaaa atggcgtgat tcagggagga ttttccagaa
    26941 catcaacgcc gaggccagcg cgaaacaacc gattgccgcc agagcaattc gccagttaaa
    27001 aaagtccgtg aagacaccgc taattaagcg tccgctcatg ccgccaattg agttgccgct
    27061 gatatacaac cccattgaaa aggccacgaa actagggtgg atttcctcgc taagataagt
    27121 catgccaacg gctgccacgc cacttaacga aagcccaatc aaggcgcgca taatcaaaat
    27181 gccgtgccag ctggtcatca ttgtcgaaag taacgtacaa atggaggcca acagtagcgc
    27241 cgtgaccatc actggtttgc gaccaatggc atcggatagc gggccagtaa acagcaaacc
    27301 gatagccaac atcgccgttg aaatggacag tgaaatacta ctgttcgcag gcgttaaacc
    27361 aaactcctgc gaaagcaccg gaaggatagg ttgcacacaa tagagaagtg cgaaggttgc
    27421 cagtccggca gagaaaagcg ccagggtgac gcgcataaat tgcggcgtac cgcgtttaat
    27481 aaaatgattt ggctgagaaa tgctttgctt gtcagtgtcg cttgccggag cgccatcaac
    27541 agttgtagta cggctcactt gaaatccttg ctaaatatgc ctgtggatca ggcttatgaa
    27601 tagattagga aaatcgaatt gttctgtcta atatattaat aatctcaaat aagatgtttt
    27661 aaatatgaat attgaacttc gtcatctgcg ttactttgtt gctgttgcag aagagctgca
    27721 tttcgggcgc gccgctgccc gcctgaatat ttcgcaacca ccgctaagtc agcagattca
    27781 ggcgctggag caacaaattg gtgcccgact gctggcacgg accaatcgca gtgtattgct
    27841 gacggaagca ggaaaacagt ttcttgtaga tagtcggcaa atcctgtcta tggtggatga
    27901 tgctgccgct cgcgctgaaa ggctgcatca gggcgaagcg ggggagttgc gcattggttt
    27961 tacttcgtcc gctcctttta ttcgggcggt gtccgatacg ttatcgctgt ttcgccgtga
    28021 ttatcccgat gtccatttac aaacccgcga aatgaacact cgcgagcaaa tcgctccgct
    28081 cattgaagga acgctggata tgggattgct gcgtaacaca gcgttaccgg agacgcttga
    28141 acacgcagtc atcgtccatg aaccgcttat ggcgatgatc ccgcacgatc atcccctggc
    28201 aaataacccg agtgtaacgc tggctgaact ggcgaaagaa ccctttgtct tttttgatcc
    28261 gcacgtcgga acagggctgt atgacgatat tctcgggctg atgagacgtt acaatttgac
    28321 gcccgtcatc actcaggagg tgggtgaggc aatgaccatc atcggtctgg tttccgctgg
    28381 tctgggtgtt tcaattttgc ctgcgtcatt taaacgtgtt cagctcaacg aaatgcgctg
    28441 ggtgccgatt gctgaagagg atgcggtttc tgaaatgtgg ttggtctggc cgaaacatca
    28501 tgaacaaagt ccggctgcgc gtaactttcg tattcatctg ctgaatgctc tcaggtgagg
    28561 gaaatttcag cgaaaaagcc cgaaaaatgt gctgttaatc acatgcctaa gtaaaaattt
    28621 gacgacacgt attgaagtgc ttcaccatag cctacagatt atttcggagc gcgaaaatat
    28681 agggagtatg cggtggttgc tgaaaaccag cctgggcaca ttgatcaaat aaagcaaacc
    28741 aacgcgggcg cagtttatcg cctgattgat cagcttggtc cagtctcgcg tatcgatctt
    28801 tcccgtctgg cgcaactggc tcctgccagt atcactaaaa ttgtccgtga gatgctcgaa
    28861 gcacacctgg tgcaagagct ggaaatcaaa gaagcgggga accgtggccg tccggcagtg
    28921 gggctggtgg ttgaaactga agcctggcac tatctttctc tgcgcattag tcgcggggag
    28981 attttccttg ctttgcgcga tctgagcagc aaactggtag tggaggagtc gcaggaactg
    29041 gcgttaaaag atgactcgcc attgctggat cgtatcattt cccatatcga tcagtttttt
    29101 atccgccacc agaaaaaact tgagcgtctg acttcgattg ccataacctt gccgggaatt
    29161 attgatacgg aaaatggtat tgtacatcgc atgccgttct acgaggatgt aaaagagatg
    29221 ccgctcggcg aggcgctgga gcagcatacc ggcgtaccgg tttatattca gcatgatatc
    29281 agcgcatgga cgatggctga ggccttgttt ggtgcctcac gcggggcgcg cgatgtgatt
    29341 caggtggtta tcgatcacaa cgtgggggct ggcgtcatta ccgatggtca tctgctacac
    29401 gcaggcagca gtagcctcgt ggaaataggc cacacacagg tcgacccgta tgggaaacgc
    29461 tgttattgcg ggaatcacgg ttgcctcgaa accatcgcca gtgtggacag tattcttgag
    29521 ctggcacagc tgcgtctcaa tcaatccatg agctcgatgt tacatggaca accgttaacc
    29581 gtggactcat tgtgtcaggc ggcattgcgc ggcgatttac tggcaaaaga catcattacc
    29641 ggggtaggcg cgcatgtcgg tcgcattctt gccatcatgg tgaatttatt taacccacaa
    29701 aaaatactga ttggctcacc gttaagtaaa gcggcagata tcctcttccc ggtcatctcg
    29761 gacagcatcc gtcagcaggc ccttcctgcg tatagtcagc acattagcgt tgagagtact
    29821 cagttttcta accagggcac gatggcaggc gctgcgctgg taaaagacgc gatgtataac
    29881 ggttctttgt tgattcgtct gttgcagggt taacattttt taactgttct accaaaattt
    29941 gcgctatctc aatttgggcc aggaaagcat aacttagact ttcaaggtta attattttcc
    30001 tggtttatat ttgtgaagca taacggtgga gttagtgatg ctgaagcgtt tctttattac
    30061 cggtacagac acttctgtag ggaaaacggt ggtttcccgc gcattgctac aagcgttagc
    30121 ctcccaggga aaaacggttg cgggatataa acccgtagcg aaggggagca aagagacacc
    30181 cgaagggctg cgtaataaag atgccctggt gttgcagagt gtttcaacca tcgaactgcc
    30241 ttatgaagca gttaatccta tcgcgttaag cgaagaagaa agtagcgtgg cgcacagttg
    30301 cccaatcaat tacaccctca tttcaaacgg cctggcaaac ctgaccgata aagtcgatca
    30361 tgtcgtggta gaagggactg gcggctggcg cagtctgatg aatgatttgc gtccgctctc
    30421 tgaatgggtg gtgcaggaac aactgccggt gttgatggtt gtcggtattc aggaaggttg
    30481 cattaaccat gcactgctaa cagctcaggc gattgccaac gacgggctgc cgctcattgg
    30541 ctgggtggct aaccgaatca acccaggact ggcgcattat gcggaaatca ttgatgtgct
    30601 cggtaaaaaa cttccggcac cgctcattgg tgaactgcct tatctgccgc gcgccgaaca
    30661 gcgtgaactg gggcaataca tccgcttagc tatgcttcgc agtgtgctgg cggtagatag
    30721 agtcacggtg taacgtccgc gaaattaccg acgcaattac gcaggcaatc aataaaccgg
    30781 ggagtagctg atactccccg gtcatttcac atatcatcaa cgtcgacata gtcggcgcgt
    30841 gcgtggtcgc cgccaacagt gtcgccatcc cggtcaatcc gagtaaaagc gtaatttctt
    30901 cgccatcagg taaccataat cccaggctac gaccatacaa catgccaatg gcaagaccga
    30961 taaatagcgt cggtgtaaag acaccaccgg gcgcgccaga accactactc gccagcacgg
    31021 cacacagttt acagaggaag atcccggcaa tgatcattaa cagtggcgga gcggttaaaa
    31081 aggattgtac ggtgctatag ccgttgcccc acactgcagg tgtgaacagg gaaagaagac
    31141 ccacgatcaa cccgcccagt gccagttgcc agggcggcgc aagcttgaga ctcacaaatc
    31201 cacgatgaca ggcgttcatt aacgttaaca acagtggtcc gcacagacct gccagcacac
    31261 ctgtactgat aatcagcgca tagtcacgag cctgaaccgt cactgaaagt tgtacgctgt
    31321 agagtaatgc gtcgctatga ttaataagat tgctaaccag caacgccacg acggcggaaa
    31381 taatcaccgg gccgagagag gccaacatca tagtgccaaa cagcacttcg gctataaata
    31441 aactaccagc aagcggggcg cgataggccg cagccattcc cgccgcagct ccacaggcga
    31501 tccataattt ccactcctgg cgtggcgtaa aacgttgggc aaaacacgag gctgcaaggg
    31561 cagctaaaag aatcatcgca ccttcgcgac caattgcact gccgctggtt actaccagca
    31621 gagaggcaag cgatttaacc agacttgctg cgtaatcaaa ctgaccatcg gtttgcaacg
    31681 cttccatgta atcggtcggc gcatgagggc gttgctgggt aaatttctgc cagcccatca
    31741 gcaacaaacc cgccgccagt ccgccgagcg ccggggttag cagccgtcgc cacggggaaa
    31801 gatttgtcgc tgcattgacc agactgccag agtcattatt gaggaacagc cactccagta
    31861 gcagcatcgc atgacgaaac ccggcaacgg caaaggccgc aagaataccg acgattgttg
    31921 cgataagcag acggcggaac atagtgcgca gatccggata gatgtgtaga tgatgcatga
    31981 gcagaaatgg gcaatgaaac acgggcgact attttgcggc aaaagaggcc agccgcaaaa
    32041 gcagtgtgtg ctttaagaga taaaaaaaac gtgacactgt aacctattaa ttgccgaatt
    32101 gcgtgtaatc gtcaccatcc ggcaataata cggtgatcct atcgaaacag cggtttaacc
    32161 gcgacaggaa tcaacagttg tgattgccat tgcgccagcg ttaagcgagc gagttcaccc
    32221 agtgcacggt agaaagggtg ttctgctttt tcgataaaaa cgtcaagaaa acgtgttgac
    32281 cacggaaaaa ggtgccatgc cagcaattct tcgcattctg tctggcgacc attctccgcc
    32341 aaccacgcag ccatcagcag cagtgaacca aaattatctt ccggttcgtt ttgcttcatt
    32401 tcgaactgaa tgcctttctc gcgcatccac tgacgaagtg ccaatgttga atcgccaaac
    32461 agcacagatt cgcgatccag ccagaccgat ccccacggcg gagacggcag tgcccacggg
    32521 ccgacaaaca aacgctgcca ggcctgggcg tgagtctctt cacattgtgt ctgaaaagcc
    32581 gtcaccagcg gcgctaatga cgcttctggt agaggccact gagtttccca gccgtcattg
    32641 gtgagtaccg caaccagagg tgcggcttcc gcactctctg gagcgtaata aaacagcgcg
    32701 cccaacacgc gcgccgcaac agaaaaatta tcttgctgtg aaaaatgggt cattcctaac
    32761 atcctgaaat gtgcgggttg ccccgcacca atttgttaac ctgcaatagc cattcctacc
    32821 gtcatgtgca ggccataaaa gagcacacgc ccgatcatct caccgccaag aatgaggatt
    32881 agccccagaa caagtccggc aacgtgaggt tcacggcgac gaatgagcgg acaaagccag
    32941 catccaagac ctgcgcataa caataccaca cgccagacct gtaaggaggc gtaatctggt
    33001 accagtgcgc tggcttgttg tacggatgag tgaatagacg ccagagacaa accttgcagc
    33061 acaatcaacc cggcacaagc gatcagcgcc agaatgctaa tgatggcaaa tggtgtggta
    33121 ttaaatgtaa cgcgggctgc acgcagaatt gtggcagcaa gtattggacc gctcaacaat
    33181 accgtcagga agaaagccag cgtagtgtaa ccgttatgcc aggttggcac agtgtcgatt
    33241 tgatacacgc aggtcatcat ccagacgaaa atgatgccga gtgccatgct gacaagtaac
    33301 cagagtttcc ccaacgcttg cggcatttta ccgatgaccg ccaccagcca ccataatccg
    33361 ccaacggcaa aaaatatgga accggcagca atctcgttac tcagaccaga agctccgatt
    33421 ctattcagcg agttaaacgc ccgcagtggc gatcccaggt gcatgacaga ggcaataaac
    33481 ccgatgccca tcaacagcca gaggaaaaac atgccacgaa taatgtgctg acggtctgcg
    33541 tcatttttgg cggcgaacca gccaattccg ctaacaatca gcgcgcctac tacgcattga
    33601 cccaatacgg taaagataac cagtggccat tcatgccatc catttcccat tttacacttc
    33661 ctccggatta gccagataac cagtggtatc gccggtcggg cggctgttgg cgttaggttt
    33721 gataacgata ttgggttttg tgaaatgcgc gcgcggcagt ggcgcgacgg cagccagagt
    33781 gccgtgcttc tggcgcaatt cttcaattgg accgaactca agtgcacgca gtgggcagga
    33841 ttcgacacat atgggttgtt tcccctcggc gacgcgcgaa taacaaccat cgcacttcgt
    33901 catgtgccct ttttcagcat tgtactgtgg cgcgccgtac ggacaagcca tgtggcagta
    33961 gcggcagccg atacaaacat cttcatcgac caccacaaag ccatcttctc gtttgtgcat
    34021 tgcgccgctg gggcagactt tggtacacgc cggatcatcg cagtggttgc acgaaattga
    34081 gagatagtag gcaaagacat tctgatgcca gacgccatta tcttcctgcc agtcgccgcc
    34141 agcatattca taaatacggc ggaaactgac ttccgggcca agatctttaa aatctttgca
    34201 cgccagttcg caggttttac agccagtaca gcggctggaa tcgataaaaa atccatattg
    34261 tgtggtcatg ggctactcct taaacctttt cgatctggac aagattgctg tgcgacgggt
    34321 ttccctttgc cagcggtgaa gggcggtgag aggtcagaat accgttaact gcagtggata
    34381 ggtcccccgt aggggatcgt tccaaccgtc gaaacctggg gtatacgctg gcagtggatg
    34441 aataatttca tcttttttca attcccaggt atccgcaatt gtcgccagtc gttcagaata
    34501 aatttcgatt tttcccgaag gtgttttcaa cgggtttgcc tgtggatcta cacggaatgc
    34561 gcggaaagcg acgtagtgtt cttccgggca ttttttctta aagatcccgg tcgttttcat
    34621 ctcctcgtag tcgggcatct cagggttacg ttccttcgtt ttcgcatgga gatatttgat
    34681 ccattcatgc tgactgcgac cttcagtaaa ggtttgataa acgtctggtc ctaagcgttt
    34741 ggcgacttca ctcagcatcc agtagatggg tttgcgttca aattttgctg aggttgcggg
    34801 ttgggcgagg atcacatagc ccatattccc ggcagattca tgagagataa ggtcttcttg
    34861 ctctgttggc atcaggtcgg gtaacaggat atcgcaatac ttagccgagg cagtcatgaa
    34921 gtggtcaatg ccaacaatca tctcgcactt gctgtcatcc tgaagcacct catgggtgtg
    34981 attgatgtcg ccatgctgat tgatcaatgt gttactggcg tagcaccata aaaacttgat
    35041 ggggacatcc agtttttctt ttcctcgaac accatcacgg gtcgcggtca tttccgtacc
    35101 atggtcgatg gcatctgtcc atgtaaagac ggaaagccgc tcatccgcgt ttctgacggg
    35161 ttatttccga acataacgac cagtttcgta ttggcgatat catccgggct gttgccatca
    35221 ttggcaccga acatataact cattgcggca ctgatctgtg cggtactgta gctgccatag
    35281 cgactgagaa aaccaccgca agagttcatc agacggtacg ggacgtttga gttggtgatg
    35341 tttccgccat ctacgcctgt tccatagaga acatgtacag cctcattgcc gtaatctttt
    35401 aggatccgcc gaagattatc actgatggta tccagggctt cgtcccaact tatccgttca
    35461 aatttacctt caccgcgctt gccgacgcgc ttcatgggat atttcaacct gtcaggatga
    35521 ttcatccgtc ggcggataga gcgcccgcgt aaacatgccc gaacctgatg attaccgtaa
    35581 acgtcgtcac ctgtcgtatc agactccacc cagtacacgg tgtcatcttt cacatgcaaa
    35641 cgtaacagac agcggctccc gcagttaacg gtgcaggaac tccagaccgc tttctcttct
    35701 accggtgcct gtgccgctcg gaccatttgg gaaaacggca aagtgaaagc actgcttgcc
    35761 agcgcgagac tgccaagtgc ggaggttttc atcagacttc tacgactgat ttcagccgac
    35821 atgagcgcct ctgtgttatg gattttcatc attactcact tattgctttt caaacaaaat
    35881 gtcatgtcaa aatttatggc cgtagtgggt tatatttttt cgatctcgac cagattagtg
    35941 tgctgcgggt ttcccttcgc cagtggtgaa gggcgcagag tggttagcgt attcacacag
    36001 ccgccgtggt cgattttatc gccagacata ttggcctcgt gccaggctcc ctggcccata
    36061 gcactaactc cagggagaat gcgtggtgtc actttggctg gtagccgaac ttcgccacga
    36121 tggttaaaca cccgcaccat atcgccgttg gcaatcccac gtttctgtgc atctataggg
    36181 ttgatccaca cttcctgacg gcaggctgcc ttcaggacat caatgttgcc gtaggtcgag
    36241 tgcgtacggg atttgtaatg gaaaccaaac agttgcagtg ggaaggtact acgttcaggg
    36301 gagtcccacc cttcaaaggt tgaggcataa accggcagtg ggcttatcac ttcatctttt
    36361 tccagttccc aggtacgggc aatttccgcc agcttgctgg aataaatttc aatcttaccg
    36421 gaaggcgttt taagtggatt tgcctcgggg tcgtcacgaa atgctttgta ggcgacaaaa
    36481 tgaccattgg gatctttacg cttatagata cccatttttt ttaattcgtc gtaagacggt
    36541 aacgccggat ctttggcaag cattttggcg tacagatgtt gtaaccattg ttcttgcgtg
    36601 cgaccttcag tgaacttttg atagacgtca ggtccaagac gtttcgcgac ttcactcagg
    36661 atccagtaaa ttggtttgcg ttcgaatttt tcgctggtga caggctggag gaaaatgaga
    36721 tatcccatgt taccggcgta gtcgttagga ataatatctt cctgctcaac ggtcattagg
    36781 tctggcagca gaatgtcggc atattttgcc gatgaggtca taaagttttc gatgaccaca
    36841 atcatttcgc atttcgattc gtcctgcaga atttcatgcg ttttgttgat gtcagaatgc
    36901 tgattaacca gggtatttcc cgcgtagttc cagatgaact taatgggcac atctagttta
    36961 tctttgcccc ggacgccgtc gcggattgcc gtcatttgcg ggccatgatc gatagcatct
    37021 gtccaactga agcaggagat tgacgttttg accggattat ccagcaccgg caggcgttcg
    37081 atggtaatgg tgtaggtcga ttcacgcgca ccactatttc cgccgctgat gccgacattg
    37141 cccgtcaaaa taggcaacat agcaatagcg cgtgccgtca gctcgccgtt tgcctgccgt
    37201 tgcggccccc agccctggca gatataagcg ggttttgctg tgccaatttc acgcgccagt
    37261 ttgatgatac ggtctaccgg gatacctgta atttgcgaag cccactgcgg cgttttcgct
    37321 gttttatcat caccttcacc aagaatatag gctttatagt gaccattttt gggtgcatct
    37381 gcgggtaagg ttttttcgtc atagccgacg cagtatttat cgagaaaagg ttgatcaacg
    37441 agattttcgt taatcaatac ccaggcaata cccgcaacca gcgcggcatc ggtgcccggg
    37501 cgaataggaa gccattcatc ttcacgacca gcagccgtat cggtatatcg cggatcgata
    37561 acaatcattt ttgcgttcga tttctcgcgc gctttttcaa gaagataagt gatgccaccg
    37621 ccgctcatgc gggtttcagc cgggttgtta ccaaacatca cgaccagctt gctgttttca
    37681 atatccgtgg tgctgttgcc atcattactg ccgtaggtgt agggcatggc acaggaaatt
    37741 tgcgcagtgc tgtaggagcc atactggttt agtgaaccgc cgtagcagtt catcaggcgt
    37801 ttgaccgccg aggctgatgg agaagagcgg gtcatattgc cgccaacaat ccccgaagag
    37861 tactgaatat atacagcctc attgccatat tgttcgacgg tttttttcag gctactggcg
    37921 atagtatcca gggcttcatc ccagctaatc cgttcgaatt tgccttcgcc gcgtttgccc
    37981 acgcgtttca ttgggtaatt caggcgatcg ggatgattaa tacgccgacg gatggagcga
    38041 ccgcgcaaac aggcgcgtac ctgatggttg ccatacttgt cgctgccggt gttgtcagtt
    38101 tccacccagg tcacttcatt atctttaaca tgcagacgaa gtgcacagcg gctaccacag
    38161 ttgacggaac aggcacccca gaccactttt tcgctggcct gttgtaccgc tgctgctgca
    38221 ctgcgcaggg taaacggcaa agaaaaaccg cctgcagcca gcgccagaga acctatcgca
    38281 gtagatttaa cgagtgttct gcggctgatg cccaccattt gttcattttt ggacataact
    38341 cactccctgt tctttatcgt tatataaatg tttatatatt gaatatttag cgcgctaaca
    38401 atagagggaa tctacccatt tggggttaat aattattaat ccatatcaat agaagggtat
    38461 gagtaataag gtggggttat gttgaatgtt caaatcgccg gatgtgtcgc atccggcgtt
    38521 cagtcgataa tgtgttactg cggttcggca ggcgcgccat cctgggtaga ctgcgcggga
    38581 gcagagacgt taccgctggt ggtacgggtg tagagaattt tatgcgtatc attagcgcaa
    38641 tgcccgacga cctgggaatc aggctgatca acctggtcat tgggtacaat acttaacgtg
    38701 aagctgcttt cgggtacgcc attattgata atgcgctgtg atatatcgct ctgtatgcgc
    38761 tcacaggatc ccggcgcggc gagtaccgtg ggtgaggcga gggcgagcag aagcgcggca
    38821 cagtaggttg agtgtttcat cataagctcc ttacgcgaag ataacttctt taagcatagc
    38881 atttaacgtg taaagtactg tatttgctac tatgattgag aatcatctct actctcaggt
    38941 gactgttgtg aaatacaaat tactgccatg cttactcgcg atattactca caggatgtga
    39001 ccgcacagag gtaacacttt catttacccc ggagatggcc agtttctcta atgaattcga
    39061 ttttgatccg ctgcgtggtc ccgtaaaaga tttcactcag acattaatgg atgagcaagg
    39121 tgaagtgacg aaacgtgttt cggggacttt gtcggaagaa ggctgttttg attctctcga
    39181 attactggat ctggaaaata ataccttggt tgccctggta ctggatgcca attattaccg
    39241 tgatgccgag acgctggaga aaagagttcg tttgcaggga aaatgccagc tagcagaatt
    39301 accttctgcc ggggtgagtt gggaaaccga tgataatggt ttcgtgatta aagccagcag
    39361 caaacagatg cagatggaat atcgctatga tgatcagggg tatccgctgg gtaaaaccac
    39421 gaaaagtaac gataaaacat tatctgtcag cgccacgcca tcaacggacc cgatcaaaaa
    39481 attagattac actgctgtta ctttactgaa taatcaacgg gttggtaatg taaaacagag
    39541 ctgtgaatat gacaatcacg ccaatccggt ggactgtcag ctaatcattg ttgatgaagg
    39601 agtaaaaccc gccgtcgaac gggtttatac catcaaaaat acgatcgatt attattaata
    39661 ctattgtgcg gtcggcttca ggagagtctg acccggtgtt ttgtgctcag ccagatactg
    39721 atgctggaat atacacatgc gaatggcatt acgatattga ccattaataa agaactcatg
    39781 catcaattca ccttcaaccg taaagccaag cttgcggtaa atgtgaatcg ctttttcatt
    39841 ctctttatca acgatcagat acagcttata gagattgaga acggtgaagc catagtccat
    39901 tgctaatttg gcggcacggg ttgccagacc tttcccctga tactccgggg agataattat
    39961 ctgaaattct gcgcggcgat gaacatggtt aatttccacc agctccacca gaccggcttt
    40021 ttcgccgtca cattccacca caaagcgccg ttcgctctga tcgtgaatat gcttatcata
    40081 cagatcagag agttcaacaa aggcttcgta gggttcctca aaccagtaac gcatcacact
    40141 ggcgttattg tcgagttgat gtacatagcg taaatcttca cgctccagcg ggcgtagctt
    40201 aacactgtgg gcgcttggca taacgtgtcc ttacattcct taaatcaata acaggttagg
    40261 ggataataac gcggccagtt cgacggtcca ggcagcgcaa agtatttggc tcccagtagg
    40321 cattgatgtt ggcgctttgc tcacatttat cgcggttatc aaaagcagcg tcggctttat
    40381 cccactcttt ttcagtgcgt ttattcactt tctggcgcag attacgcgtg tcattccatt
    40441 gctctttttc catagcggcg cgctggcggc tttgtgcact gtcgccagac tcaatcacca
    40501 gtttgttagt ttcggcatga acagttgtgc tcaataccag tgcgcaaggc agcagaaaag
    40561 cgagcaggcc gattcgtttg ctgagagtga ttttcataat tcattccctg tatgaatgat
    40621 taaagctgat tctacaccat ccactgcgaa cgcaaaacgt tcaaggaggg tgtttatatt
    40681 gatgatatta tgtcgcccta taactataca tgatgtcaat aagtgacaaa gatgattaaa
    40741 acaacgttac tattttttgc tactgcgctg tgtgaaatta ttggatgctt tctgccctgg
    40801 ttgtggttaa aacgaaacgc cagtatctgg ctgttgcttc cggcggggat ttcactggca
    40861 ctgtttgtct ggttgttaac gttgcatcct gcggcgagtg ggcgtgttta cgcggcttat
    40921 ggtggcgttt atgtttgcac ggcgttgatg tggctgcgcg ttgtggatgg cgtgaaactg
    40981 actctttatg actggacggg ggcgttaatt gcgctttgcg gcatgttgat cattgttgcg
    41041 ggctgggggc gcacgtagga acataaatcc attttatcaa taagatacga ggaagtgtca
    41101 gctgacaaaa ggtattctat ttcatctttt gtcaaccatt cacggcgcaa atatacgcct
    41161 ttttttgtga tcactccggc tttttttgat cttcatactt gtatggtagt agttcagttg
    41221 cgtagatttc atgcatcacg acaagcgatg caaggaatcg aacatgaaga tcgtaaaggc
    41281 tgaagttttt gttacctgtc cggggcgtaa tttcgtcaca ttaaaaatca ccactgagga
    41341 cggtattacg ggccttgggg atgccaccct aaatggacgt gagctttccg tggcctctta
    41401 tttgcaggat cacctttgtc cgcagcttat tggtcgcgat gcacaccgta tcgaagatat
    41461 ctggcagttt ttctataaag gtgcttactg gcgtcgcggt ccggttacga tgtcggccat
    41521 ttcagcggtt gatatggcgc tgtgggatat taaagccaaa gctgccaaca tgccgcttta
    41581 ccagttactc ggcggcgcgt ctcgtgaagg ggtgatggtt tattgccata ccaccggtca
    41641 cagtattgat gaagctctgg atgattatgc ccgtcatcag gagctgggat tcaaagccat
    41701 ccgcgtgcag tgcggaatcc ctggtatgaa aaccacctac ggcatgtcga aaggtaaagg
    41761 tctggcttat gaacccgcaa ccaaaggaca gtggccggaa gagcagctgt ggtcgacgga
    41821 gaaatacctc gatttcatgc cgaaattgtt tgacgcggta cgtaacaagt ttggatttaa
    41881 tgaacatttg ctgcatgaca tgcaccatcg cttaacgcct attgaagcgg cgcgctttgg
    41941 taaaagcatt gaagattatc gcatgttctg gatggaagac ccgacgcctg cggaaaacca
    42001 ggaatgcttc cgtctcattc gccaacatac cgtcacaccc atcgcggtgg gtgaagtctt
    42061 caacagcatc tgggactgca aacaactgat tgaagagcaa ctcatcgatt atatccgcac
    42121 cacgctgact catgcaggcg gaattaccgg tatgcgtcgg attgccgatt ttgcttcgct
    42181 gtatcaggta cgtactggct cacacggtcc ttccgatttg tcaccagtct gcatggctgc
    42241 ggcgctgcac tttgatctgt gggtccccaa tttcggtgtc caggaataca tgggttattc
    42301 cgaacaaatg ctcgaagtct tcccgcacaa ctggactttc gataacggct atatgcatcc
    42361 gggagaaaaa ccgggtcttg gcatcgaatt cgatgaaaag ctggcggcga aatatcccta
    42421 tgaacctgct tatctgccag tcgcacgtct ggaagatggc acgctgtgga actggtaagg
    42481 agtaaggtaa tgaaaagcat tttaattgaa aaaccgaatc aactgtcgat tatcgaacgt
    42541 gaaataccca ccccgtcagc gggtgaagta cgagtaaaag tgaaacttgc cggaatttgt
    42601 ggttcagata gccatattta ccgtgggcat aatccttttg cgaaatatcc gcgcgtcatt
    42661 ggtcatgaat tctttggcgt cattgatgca gtgggtgaag gcgtggaaag cgccagagtc
    42721 ggtgaacgcg ttgctgtcga tccggtggtc agctgtgggc attgctatcc gtgctctata
    42781 ggtaagccga acgtttgtac gacacttgct gtattaggtg tgcacgctga cggtggtttc
    42841 agtgaatatg ccgtggttcc ggcaaaaaat gcgtggaaaa ttcctgaagc agtggccgat
    42901 caatatgcgg tgatgatcga accttttacc attgcggcta acgttaccgg tcatggtcaa
    42961 ccgactgaaa atgataccgt tctggtttac ggtgccggtc caatcggcct gacgatcgtt
    43021 caggtattaa aaggcgtcta taacgttaaa aatgtgattg ttgccgatcg cattgatgaa
    43081 cgactggaaa aagcgaaaga gagcggggca gactgggcga ttaataacag ccagacacca
    43141 cttggcgaga ttttcgatga aaaaggcatc caaccgacat tagttatcga tgccgcttgt
    43201 catccttcaa tcttgaaaga ggccgtaacg ctggcttctc cagcggcacg tattgtattg
    43261 atgggcttct ccagtgaacc gtctgaagtg attcagcaag gaattaccgg aaaagaactc
    43321 tctattttct cttcacgctt aaatgcaaat aaattcccgg tcgttatcga ctggttaagt
    43381 aaagggttaa ttaaaccaga aaaactaatt acccatacgt ttgatttcca gcatgttgcg
    43441 gatgccatta gtttatttga acaggatcaa aaacattgct gcaaagtctt actcactttt
    43501 tctgaataat accaataacg gcgaataagt agtacgcatc ttacctcttt tttagagata
    43561 accattatga caatagaaaa acacgaaaga agcactaagg atttggtgaa agcagcagta
    43621 tcgggatggc tgggcactgc gcttgaattt atggatttcc agttatattc gctcggcgca
    43681 gcgttagtgt ttcatgaaat attttttcct gaatcatcaa cggcaatggc gttaattctg
    43741 gcaatgggaa cctatggtgc aggttatgtg gcacgtattg tcggagcatt tattttcggc
    43801 aaaatgggcg acagaatagg gcgtaaaaaa gtgctcttta ttaccatcac catgatgggg
    43861 atctgtacca ccttaattgg tgtgttaccg acttatgcac aaattggtgt ttttgccccc
    43921 atcttgctgg tgacgctgcg tattattcag gggttgggtg caggtgcgga aatttccggt
    43981 gccggtacga tgctggcgga atatgcgcca aaaggtaagc gcggaattat ctcctcattt
    44041 gtggctatgg gaactaactg cggaaccttg agcgcaacgg caatctgggc ctttatgttc
    44101 ttcattctca gtaaagagga actgctggcg tggggatggc gtataccttt cctggcgagc
    44161 gttgtcgtga tggtctttgc tatctggttg cgtatgaatc tgaaagaaag cccggtcttt
    44221 gagaaggtta acgacagcaa ccaaccgaca gcaaaacctg cacctgctgg tagcatgttc
    44281 cagagcaaat ccttctggct ggcaacaggg ctgcgttttg gtcaggctgg taactcaggt
    44341 ttaattcaga ctttccttgc aggctattta gtgcagacgt tattgtttaa caaagcaatt
    44401 ccaacagatg cattgatgat cagttcgatt ctcggcttta tgaccattcc gttccttggt
    44461 tggttatccg ataaaattgg tcgccggatc ccgtatatta ttatgaatac ctctgcgatt
    44521 gtgctggcat ggccaatgct ttctatcatc gtagataaaa gctatgcccc gagcaccatt
    44581 atggttgcac tgattgtgat tcataactgt gcggtgcttg gattatttgc tctggaaaac
    44641 attaccatgg cagaaatgtt cggctgtaaa aaccgcttta cccgaatggc tatttctaaa
    44701 gaaattggtg gtcttatcgc ttccggtttt ggtcctatcc tggcggggat tttctgcacc
    44761 atgacggaat cctggtatcc gatcgccatt atgatcatgg catattctgt gattggttta
    44821 atctctgcgc tgaaaatgcc agaagtgaaa gaccgtgatt taagtgcgct gcaagacgcc
    44881 gcagaagatc aaccacatgt tgtaagagct gcgcaaccgt ccagaagtct gtaaatcctc
    44941 aatcccttct cttaccgg
//
LOCUS       DAPOXO010000034        44252 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPOXO010000034 DAPOXO010000000
VERSION     DAPOXO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 44252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44252
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.034"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            410..4339
                     /locus_tag="ROH59_002276"
     CDS             410..4339
                     /locus_tag="ROH59_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_109867760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX4804753.1"
                     /translation="MNRIYSLKYCHLTQGLIAVSELASRVSSKTGRKLLAIFIVSALS
                     YGAAEYACAAQMDTRNFWIRDYLDLAQNKGAFQPGAYGVKTPLKNGGEFSFPEVTIPD
                     FSPVSAKGATTAIGNAYSVTASHNGTIHHAIKTQTWGQSDYHYVDRVTKGDFAVQRLD
                     KFVVETAGATEHADFNLSAAEALERYGIEFNGKKQIIGFRVGAGATGVTSYGVGQTYN
                     PLLRSASMFQLNWNNMYASNNTGGFYNEVTGGDSGSGFYLYDNQKKKWVILGTLTGKV
                     FSSKDTWAFFARYDQNTVDILKNTFTQEVNLNGQKMTVNNKNIAINDKITAIELTKSN
                     KNKDLKFHGGGSIELTDNLNSGTGGLIFDEGQHYSVIGKDKAYKGAGVEIGKDTVVDW
                     SVKGEANDNLHKTGAGTLNVNVAQGNNLKTGDGTVFLNAEKAFNAIYVASGRGTVKLG
                     QADALDKNSDYRGIYFTSRGGTLDLNGFSQSFKKIAATDVGTIITNTSDKTATLSLQN
                     PSRYVYHGSITGNTNIEHTGTQKSADSSLIIDGNINTRNDITVRNSQLRLQGHATSHA
                     IFREGPRHCYVPGVLCDKDYVTDFARLESEANKKNNSAYKTNNQVASFDQPDWETRHF
                     RFKTLNLENSEFTTARNSVVEGDIVASNSTLKLGGDVPVFIDMYDGINITGNGFGFRQ
                     DVREGRSADDGSSSYTGKITLQKGSTLDINNRFIGGIEAHDSKVNVTSPDALLQNSGV
                     FVNSTLSVRDGGHLTAQKGLYSNGRVQIGKKGTLSLSGTPENGADNTWMPVLTYMTEG
                     YDLTGDNATLNISQQAHVSGDVHATSSSSIRIGSENPGSVSSSVSPVLAAGLFSGYNA
                     AYYGAITGGKGNVSMNNGLWQLTGDSDINSLTTRNSRVQSEENGAFRTLTVKTLDATG
                     SDFVLRTDLKDADKISITEKASGSDNTLNVSFMKNPSPGQSLNIPLVSAPAGTSGDIF
                     KAGTRVTGFSRVTPTLRVDTTGGSTKWILDGFRTEADKAAAAKANSFMNAGYKSFMTE
                     VNNLNKRMGELRDTNGDAGAWARIMNGAGSADGGYSDNYTHVQVGFDKKHALDGVDLF
                     TGVTMTYTDSSADSDAFSGKTKSVGGGLYASALFNSGAYIDLIGKYIHHDNDYTGNFA
                     GLGTKHYGTHSWYAGAETGYRYHLTEDTFIEPQAELVYGAVSGKTFRWKDGEMDLSMK
                     NKDFSPLIGRTGIELGKTFRGKDWSVTARAGTSWQFDLLNNGETVLRDASGEKRIKGE
                     KDSRMLFNVGMNAQIKDNMRFGLEFEKSAFGKYNVDNAINANFRYMF"
     gene            4553..4825
                     /locus_tag="ROH59_002277"
     CDS             4553..4825
                     /locus_tag="ROH59_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX4804754.1"
                     /translation="MEIREGHNKFYINDEQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKTREYDDIRS"
     gene            5053..5349
                     /gene="ghoS"
                     /locus_tag="ROH59_002278"
     CDS             5053..5349
                     /gene="ghoS"
                     /locus_tag="ROH59_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDX4804755.1"
                     /translation="MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEY
                     GIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLSIMTVDDYFRQFYK"
     gene            5377..5550
                     /gene="ghoT"
                     /locus_tag="ROH59_002279"
     CDS             5377..5550
                     /gene="ghoT"
                     /locus_tag="ROH59_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system toxin GhoT"
                     /protein_id="HDX4804756.1"
                     /translation="MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITW
                     PMSLPVALLFSLF"
     gene            complement(5669..7186)
                     /gene="lysS"
                     /locus_tag="ROH59_002280"
     CDS             complement(5669..7186)
                     /gene="lysS"
                     /locus_tag="ROH59_002280"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDX4804757.1"
                     /translation="MSERETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDH
                     TSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK"
     gene            complement(7423..8880)
                     /gene="dtpC"
                     /locus_tag="ROH59_002281"
     CDS             complement(7423..8880)
                     /gene="dtpC"
                     /locus_tag="ROH59_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpC"
                     /protein_id="HDX4804758.1"
                     /translation="MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDN
                     HAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL
                     YLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVM
                     LCLAPVFFTLLLENDWSGYLLAIVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTL
                     FWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVMLAGVVLAWLASPESR
                     GNSALRVWLKFAFGLLLMACGFMLLAFDARHAAAGGQASMGVMISGLALMGFAELFID
                     PVAIAQITRLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQ
                     MGEWTLACVAIIVVLAFATRFLFSTPTNMIQESND"
     gene            complement(8939..11086)
                     /gene="cadA"
                     /locus_tag="ROH59_002282"
     CDS             complement(8939..11086)
                     /gene="cadA"
                     /locus_tag="ROH59_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HDX4804759.1"
                     /translation="MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLK
                     LIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISF
                     FEYALGAADDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTN
                     GTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWV
                     PYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWF
                     FDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFG
                     IPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRV
                     KNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAF
                     QKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKEESKK"
     gene            complement(11166..12500)
                     /gene="cadB"
                     /locus_tag="ROH59_002283"
     CDS             complement(11166..12500)
                     /gene="cadB"
                     /locus_tag="ROH59_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HDX4804760.1"
                     /translation="MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWI
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
                     TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALM
                     ILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVL
                     GCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH"
     gene            complement(12866..14404)
                     /gene="cadC"
                     /locus_tag="ROH59_002284"
     CDS             complement(12866..14404)
                     /gene="cadC"
                     /locus_tag="ROH59_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HDX4804761.1"
                     /translation="MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHS
                     GEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMV
                     PVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTTTPPEQSPVKSKRFTTFW
                     VWFFFLLSLGICVALVAFSSLETRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLS
                     YAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSV
                     KLVDNADGSTMLDKRYVITNGNQLAIQNDLLQSLSKALNQPWPQRMQEMLQQILPHRG
                     ALLTNFYQAHDYLLHGDDKSLDRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPL
                     DEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSW
                     LNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKF
                     LASE"
     gene            complement(15021..15096)
                     /locus_tag="ROH59_002285"
     tRNA            complement(15021..15096)
                     /locus_tag="ROH59_002285"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15061..15063),aa:Phe,seq:gaa)
     gene            complement(15203..15778)
                     /locus_tag="ROH59_002286"
     CDS             complement(15203..15778)
                     /locus_tag="ROH59_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX4804762.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            complement(15815..17512)
                     /gene="dsbD"
                     /locus_tag="ROH59_002287"
     CDS             complement(15815..17512)
                     /gene="dsbD"
                     /locus_tag="ROH59_002287"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HDX4804763.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNEASQPVSVPQQEQPT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFIMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDIWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDSQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP"
     gene            complement(17488..17826)
                     /gene="cutA"
                     /locus_tag="ROH59_002288"
     CDS             complement(17488..17826)
                     /gene="cutA"
                     /locus_tag="ROH59_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HDX4804764.1"
                     /translation="MLDEKSSNTTSVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            complement(17942..19243)
                     /gene="dcuA"
                     /locus_tag="ROH59_002289"
     CDS             complement(17942..19243)
                     /gene="dcuA"
                     /locus_tag="ROH59_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HDX4804765.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            complement(19361..20797)
                     /gene="aspA"
                     /locus_tag="ROH59_002290"
     CDS             complement(19361..20797)
                     /gene="aspA"
                     /locus_tag="ROH59_002290"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HDX4804766.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMNPAYKAKRYTDESEQ"
     gene            21134..21610
                     /gene="fxsA"
                     /locus_tag="ROH59_002291"
     CDS             21134..21610
                     /gene="fxsA"
                     /locus_tag="ROH59_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HDX4804767.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDDRDRLDHKDDRQD"
     gene            complement(21626..22882)
                     /gene="yjeH"
                     /locus_tag="ROH59_002292"
     CDS             complement(21626..22882)
                     /gene="yjeH"
                     /locus_tag="ROH59_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HDX4804768.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPANIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEQMAAAASLPKIVVQLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLFLPKRKTPENGITT"
     gene            23158..23451
                     /locus_tag="ROH59_002293"
     CDS             23158..23451
                     /locus_tag="ROH59_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDX4804769.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            23495..25141
                     /gene="groL"
                     /locus_tag="ROH59_002294"
     CDS             23495..25141
                     /gene="groL"
                     /locus_tag="ROH59_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDX4804770.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            25279..25632
                     /locus_tag="ROH59_002295"
     CDS             25279..25632
                     /locus_tag="ROH59_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HDX4804771.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PTDSQIIGQVYKCPN"
     gene            complement(25682..26551)
                     /locus_tag="ROH59_002296"
     CDS             complement(25682..26551)
                     /locus_tag="ROH59_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HDX4804772.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSAMELR
                     DLLIALESRLHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELTDDQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQDDGNLEYDTYSQPEWKHNLFNHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEVEAITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
     gene            complement(26786..27814)
                     /gene="epmB"
                     /locus_tag="ROH59_002297"
     CDS             complement(26786..27814)
                     /gene="epmB"
                     /locus_tag="ROH59_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HDX4804773.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPNDPLLRQVITSQDEFVVAPGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            27856..28422
                     /gene="efp"
                     /locus_tag="ROH59_002298"
     CDS             27856..28422
                     /gene="efp"
                     /locus_tag="ROH59_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDX4804774.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            28474..28599
                     /gene="ecnA"
                     /locus_tag="ROH59_002299"
     CDS             28474..28599
                     /gene="ecnA"
                     /locus_tag="ROH59_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HDX4804775.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            28710..28856
                     /gene="ecnB"
                     /locus_tag="ROH59_002300"
     CDS             28710..28856
                     /gene="ecnB"
                     /locus_tag="ROH59_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HDX4804776.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            29032..29349
                     /gene="sugE"
                     /locus_tag="ROH59_002301"
     CDS             29032..29349
                     /gene="sugE"
                     /locus_tag="ROH59_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDX4804777.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(29346..29879)
                     /gene="blc"
                     /locus_tag="ROH59_002302"
     CDS             complement(29346..29879)
                     /gene="blc"
                     /locus_tag="ROH59_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HDX4804778.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDREMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(29968..31101)
                     /locus_tag="ROH59_002303"
     CDS             complement(29968..31101)
                     /locus_tag="ROH59_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDX4804779.1"
                     /translation="MFKTTLCTLLITASCSTFAAPQQINDIVHRTITPLIEQQRIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMKTRVFQPLKLNHTWINVPSAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKILQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDIIINGSDNKIALAARPVKPITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNTLQ"
     gene            complement(31164..31523)
                     /gene="frdD"
                     /locus_tag="ROH59_002304"
     CDS             complement(31164..31523)
                     /gene="frdD"
                     /locus_tag="ROH59_002304"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDX4804780.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            complement(31534..31929)
                     /gene="frdC"
                     /locus_tag="ROH59_002305"
     CDS             complement(31534..31929)
                     /gene="frdC"
                     /locus_tag="ROH59_002305"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDX4804781.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            complement(31940..32674)
                     /gene="frdB"
                     /locus_tag="ROH59_002306"
     CDS             complement(31940..32674)
                     /gene="frdB"
                     /locus_tag="ROH59_002306"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HDX4804782.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            complement(32667..34475)
                     /gene="frdA"
                     /locus_tag="ROH59_002307"
     CDS             complement(32667..34475)
                     /gene="frdA"
                     /locus_tag="ROH59_002307"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HDX4804783.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGMAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            34800..35777
                     /gene="epmA"
                     /locus_tag="ROH59_002308"
     CDS             34800..35777
                     /gene="epmA"
                     /locus_tag="ROH59_002308"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HDX4804784.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            35996..37498
                     /gene="yjeM"
                     /locus_tag="ROH59_002309"
     CDS             35996..37498
                     /gene="yjeM"
                     /locus_tag="ROH59_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HDX4804785.1"
                     /translation="MPHSIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAISFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWHIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGVTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTRMSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRVVKNPQWVAE"
     gene            37596..37910
                     /locus_tag="ROH59_002310"
     CDS             37596..37910
                     /locus_tag="ROH59_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeO family protein"
                     /protein_id="HDX4804786.1"
                     /translation="MSARMSVLCCIWFIVAFLWITITSALDKEWMIDGRGINNVCDVL
                     MYLEDDDTRDVGVIMTLPLFFPFLWFALWRKKRGWFMYATALAIFGYWLWQFFLRYQF
                     CL"
     gene            complement(37941..41264)
                     /gene="mscM"
                     /locus_tag="ROH59_002311"
     CDS             complement(37941..41264)
                     /gene="mscM"
                     /locus_tag="ROH59_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HDX4804787.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VVEALQSALNALEERKGSLERIKQYQEVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     NDALNQEILQISSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTEQLAESSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPANANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(41286..42254)
                     /gene="psd"
                     /locus_tag="ROH59_002312"
     CDS             complement(41286..42254)
                     /gene="psd"
                     /locus_tag="ROH59_002312"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HDX4804788.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVDLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            complement(42351..43403)
                     /gene="rsgA"
                     /locus_tag="ROH59_002313"
     CDS             complement(42351..43403)
                     /gene="rsgA"
                     /locus_tag="ROH59_002313"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HDX4804789.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMEFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            43498..44043
                     /gene="orn"
                     /locus_tag="ROH59_002314"
     CDS             43498..44043
                     /gene="orn"
                     /locus_tag="ROH59_002314"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HDX4804790.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
BASE COUNT        11334 a        10704 c        11140 g        11074 t
ORIGIN      
        1 tccaaaaaaa ataaaaaaat acgatacaat aatgttaacg cgcggaataa atgaagaatt
       61 ccgccgcata atgatataaa ataaaaaaca ataaatataa aaacacttaa acgtcatatg
      121 cttttgttta tttcatgatt ttatttttgt agctttaccc ttcattatgc aatgtgggta
      181 tggagtcgtt attatattct aaataacctt tggcggcgca atgcaattta attaatgcaa
      241 tgtaaatatg ctaaacacac tgctataaaa tctatattgt agatgtattt tttacagacg
      301 tggggggggg gttaaactgc aattaataaa ggtaattgga agctttttat taataaaaac
      361 atagttctat tggtttgtat tatgttataa acgttatgga gtcttacccg tgaacagaat
      421 atattcactt aagtattgtc accttactca agggcttata gctgtatcag aattagcatc
      481 ccgagtatcc tctaaaaccg gtcgaaaact tctcgctata tttatagttt ctgccttgtc
      541 ttatggtgcg gctgaatatg cctgtgcagc acagatggac acccgaaatt tctggatccg
      601 tgattatctt gatctggcac agaataaagg tgcatttcag cccggagcat acggggtaaa
      661 aacgccatta aaaaatgggg gagaattcag ttttcctgaa gtaacaatcc ctgatttttc
      721 tcctgtatcc gctaaaggtg caacaactgc tattggtaat gcctacagtg ttacagcaag
      781 tcataatggc actattcacc atgccattaa aactcagaca tggggacagt cagattatca
      841 ttatgttgat cgtgtgacca aaggtgactt tgcggtccag cgtctggata agtttgttgt
      901 tgaaacagcg ggtgcaacag agcatgctga tttcaactta tcagcagcag aagcactaga
      961 gcgttatggt attgaattca atggaaagaa acaaataatc ggtttccgcg ttggagctgg
     1021 tgcaaccggt gttacatctt atggggtggg acagacatac aatccattat tacgtagtgc
     1081 ctccatgttt cagttaaact ggaacaatat gtatgcaagt aataataccg gtgggtttta
     1141 taatgaagtg acaggaggtg acagcggttc cggattttac ttgtatgata atcagaaaaa
     1201 aaaatgggtc attttgggga cactgacagg taaagtattc tccagtaagg atacctgggc
     1261 cttttttgct cgatatgatc agaacactgt cgatatcctg aaaaatactt ttacccaaga
     1321 ggtgaacctc aatggtcaga aaatgacagt taataataaa aatattgcca ttaacgataa
     1381 aataactgct attgaactga ccaagagtaa taaaaataaa gatttgaaat tccatggtgg
     1441 cgggagcatt gagctcaccg ataacctgaa ctcaggaacc ggaggattga tttttgatga
     1501 gggacaacat tattcggtta ttgggaaaga taaagcctat aaaggggcgg gtgttgagat
     1561 cggaaaagat acggttgtcg actggtcggt aaaaggggag gcaaacgata acctgcacaa
     1621 aacaggggcc gggacactga atgtcaatgt ggcccagggg aataacctga aaacaggtga
     1681 cggtaccgtt tttcttaatg cagaaaaggc tttcaatgct atctatgttg ccagtggccg
     1741 tggaacggtc aaactggggc aggccgatgc gctggataaa aatagtgatt acagaggtat
     1801 ttattttact agtcgtgggg ggactctgga tttaaacggg ttcagccagt cgttcaagaa
     1861 gatcgcggca actgatgttg gtaccattat caccaatact tctgataaaa cagcgaccct
     1921 ttccctacaa aacccctccc gctatgtcta tcacggtagt atcacgggaa atacgaatat
     1981 cgaacacact gggacacaga aaagtgctga cagcagtctg attattgatg gaaacattaa
     2041 tacacgcaat gacattactg tgcggaattc ccagctcaga cttcaggggc atgccacatc
     2101 acatgcaata ttccgcgagg ggcctcggca ctgctatgtc cccggagttc tttgtgacaa
     2161 agattatgtt actgattttg ccagactgga aagtgaggca aataagaaaa ataacagtgc
     2221 ctataaaaca aataatcagg tggcttcttt tgaccaacct gactgggaaa cccggcattt
     2281 ccgatttaag actctgaatc tggaaaactc agaattcaca actgcacgta actcagttgt
     2341 tgagggtgat attgtcgcat cgaattcaac gctgaaactg gggggcgacg ttccggtgtt
     2401 cattgatatg tatgatggca tcaatatcac cggtaatggt tttggcttcc gccaggacgt
     2461 tcgtgaagga cgctcagcag atgatggcag tagcagctat acaggcaaaa ttacactgca
     2521 aaaaggctcc acgctggaca tcaacaaccg gttcattggc ggtattgaag cccatgacag
     2581 taaggtaaac gtcacctcac cggatgccct gctgcagaac agtggtgttt tcgtgaattc
     2641 caccctttct gtccgtgacg gcggtcatct gacggcacaa aaagggctct acagtaacgg
     2701 ccgggttcag attggaaaga aaggtacgct ttccctgagc ggcacgccgg aaaatggcgc
     2761 tgataatacc tggatgcccg tactgacata catgacagaa ggctatgatt taaccggtga
     2821 taacgctacg ctgaacatca gccagcaggc gcatgtttcc ggggatgttc atgcaaccag
     2881 ttcatccagc attcgtattg gctccgaaaa ccctggctca gtttcctctt ctgtctcccc
     2941 tgttctggct gccgggttgt tcagcggata taacgcggcg tactacggtg ccatcaccgg
     3001 cggtaagggg aacgtcagta tgaataatgg cctgtggcag ctgaccggag attccgacat
     3061 caacagtctg acgacccgta acagccgggt acagtctgaa gaaaacggtg ccttccgtac
     3121 cctgacggtt aagacacttg atgccacggg cagtgatttt gtcctgcgca ctgatctgaa
     3181 ggacgctgat aaaatcagta ttacggagaa agccagcggt tcagacaaca ccctgaatgt
     3241 cagctttatg aagaacccgt ctccgggaca gtccctgaat atcccgctgg tcagtgcacc
     3301 ggccggaaca tcaggggata tctttaaggc cggcacccgg gtgacaggct tcagtcgtgt
     3361 gacgccgacg ctgcgtgttg acaccactgg cggcagtacg aagtggattc tggatggttt
     3421 caggacggaa gctgataaag cggctgcagc gaaggcgaac agtttcatga atgccggcta
     3481 caaaagcttt atgacggaag taaacaatct gaacaaacgt atgggggagc tgcgtgacac
     3541 gaacggtgat gccggtgcct gggcccgtat tatgaacggc gccggttcag ccgatggcgg
     3601 atacagtgat aactacaccc acgttcaggt cggttttgac aaaaaacatg cgctggacgg
     3661 tgttgacctg ttcaccggtg tcacgatgac ctataccgac agcagtgcag acagtgatgc
     3721 gttcagcggg aagacaaaat ccgtgggggg aggtctgtat gcttcagcac tgtttaactc
     3781 cggtgcctac attgatttga ttggtaaata tattcaccat gacaatgact acacaggtaa
     3841 ctttgccggt ctggggacga agcactacgg aacccactcc tggtatgccg gagcggaaac
     3901 gggttaccgt tatcacctga cggaagacac atttattgag cctcaggccg aactggttta
     3961 cggcgcagtg tccgggaaaa cattccgctg gaaagacggt gagatggacc tgagtatgaa
     4021 gaacaaggat ttcagcccgt tgattggcag aacagggatt gagctgggca aaaccttcag
     4081 gggtaaggac tggagtgtga cagcccgtgc cggaaccagc tggcagtttg acctgctgaa
     4141 taatggcgag acagttcttc gtgatgcatc cggagagaaa cggatcaaag gggagaaaga
     4201 cagcaggatg ttgttcaatg ttggcatgaa cgcacagata aaggacaaca tgcgctttgg
     4261 tctggagttt gagaaatccg cctttggtaa atacaacgtg gataacgcaa taaacgcgaa
     4321 tttccggtat atgttctgac aaggagaggc ccctgaagag gggcctgtag tgatgttact
     4381 cccgggttaa tgcagctagt aaaggtatgg ctctgactac cctggaaagt ggtgcccatc
     4441 gcatcactac aaattctggc aattgcgtac gtggtaacgg caagttattt aacctcaaac
     4501 gtacgtgccc gagcggtgcg ctgaaatacc gtcataaata agcgagggta aaatggaaat
     4561 acgcgaaggc cacaataaat tttacattaa tgacgaacag ggcaagcaaa tcgctgaaat
     4621 tgtctttgtg ccgaccggag agaatttagc gattatcgaa cataccgatg tcgatgaaag
     4681 cctgaaagga caagggattg gtaaacagct ggttgcgaaa gtcgtggaaa aaatgcgtcg
     4741 ggaaaaacga aaaattatcc cactatgccc atttgcgaaa cacgaatttg ataaaacacg
     4801 ggagtatgat gatattcgca gttgatggga gagtacagag tcacgatatt tttcatgctc
     4861 tccgcggtgt gatgcaggag agcatctgaa gggtaggaga tgcacaaaga atggtcagag
     4921 agagcgtttt tttgtcccaa gtcatcccct ttactgagca aaaaaaaaag aatatctcct
     4981 atatgagaat catcattcgg ggttaataag ttttgcgtcc ccagagcgtt caatattgat
     5041 aggagtcata ttatggaagg taaaaacaag ttcaatactt atgttgtttc ttttgattat
     5101 ccatcatctt attcctcagt gttcttaagg ttaagatcat tgatgtatga tatgaatttc
     5161 tcctctatcg tggctgatga atatgggata ccacgacaat tgaatgaaaa ctccttcgca
     5221 ataacgacat cgttagccgc aagtgaaatc gaagatttaa tcaggctcaa atgcttagac
     5281 ttaccggata ttgattttga cctcagcatt atgacagttg atgactattt ccgtcagttt
     5341 tacaagtagc caggaaggat aagaagaaca taaaaaatgg cactattctc taaaatatta
     5401 attttttatg tgattggtgt gaacatatcc tttgtcatta tctggtttat ctcacatgag
     5461 aaaacacata ttcgtttact tagtgcattt ctggtcggaa taacctggcc aatgagtttg
     5521 cctgtggcat tacttttttc tctcttttag gagctgtagt tgagtggacc cgctggttat
     5581 cttgaaacga agcgtctctc ctcaaaactg gatttgcgga atgacgaacg aagcagtcgc
     5641 ctgactgctt cgttcattaa agtgaaattt atttctgtgg gcgcatcgcc gggaagagaa
     5701 taacgtcgcg aatagtatga ctgtttgtaa acagcataat cattcggtcg ataccaatac
     5761 ccagaccagc ggttggcggc agaccatatt ccagcgcagt cacgtaatct tcgtcataga
     5821 acatggcttc gtcgtcacct gcagctttag cgttaacctg ttcctggaaa cgttcagcct
     5881 gatcttctgc gtcgtttaat tcgctaaaac cattaccaat ttcacgacca ccgatgaaga
     5941 attcaaaacg gtcggtgatt tccgggttaa catcattacg gcgcgccagc ggggacactt
     6001 ctgccggata ttccgtaata aaggttggct gaatcagatg tgcttctgcc acttcatcaa
     6061 agatctccgt aacaatacgc cccagtcccc agcttttctc taccgtaata ccgatagatt
     6121 cagctaatgc tttagcagca tcaaaattat ccagatccgc catatcggtt tctggacgat
     6181 attttttgat tgcttcgcgc atggtgagtt tttcaaacgg tttgccgaaa tcaaacacat
     6241 gctcgccata agtgacttta gtggtaccca gtacctcttg tgccagggtg cggaacagtg
     6301 actccgtcag ttcaatcaaa tcatggtaat ccgcatatgc catgtagagt tccatcattg
     6361 tgaactcagg attatggcga acagaaatac cttcattacg gaagttacgg ttgatttcga
     6421 atacccgttc aaaaccgcct acaaccagac gtttcagata cagctccggc gcgatacgca
     6481 ggtacatatc taaatccaga gcgttatgat gggtaataaa cgggcgagca gatgccccac
     6541 ctggaattac ctgcatcatc ggggtttcta cttccataaa gccgcgcgcg accatgaact
     6601 gacggatagc ggccagaatt tttgaacgga caacaaacgt ttgacgggat ttatcgttag
     6661 cgatgaggtc cagataacgt tgacgataac ggacttcctg atcctgcaga ccatggaatt
     6721 tatctggtaa aggacgtagt gctttagtca gcaggcgcag ctcagtacag tgaatggaaa
     6781 gctcacccgt ttgcgtctta aacagcgtac cgcgggcacc gataatgtca cccagatccc
     6841 attttttaaa ctgatcgtta taaacacctt ctggcaggct atctcttgca acgtacagtt
     6901 gaatacggcc accgacatcc tgcaacgtta caaaggaggc tttccccata atacgacggg
     6961 tcatcattcg gccagcaacc gagacttcaa tgtttaagga ttccagttcc tggttatcct
     7021 tcgcatcaaa ctcttcgtgc aactggtcag aggtatggtc gcggcgaaaa tcattgggaa
     7081 acgccacacc ttgctgacgt agtgccgcca gtttttcgcg gcgatttctc agttcatcgt
     7141 taaaatcaat agcctcattg gctccccgtg tttctcgttc agacattttg gttcctctaa
     7201 atccagcttt caatttagcg tagataaaga gacagatcgg tacactgtat tatctgcctc
     7261 gactattaat aactcagttt atcttatcga aactaacgct tacctcaagt tgatatcact
     7321 aataaataac catcaaaatg gtttaaatga cttattaatc tcgatttact agtgtgataa
     7381 actgaaagtt aatttattca taaccaattg tttttacgac agttaatcgt tgctctcctg
     7441 tatcatattc gtcggcgtgc taaacagaaa acgggtagca aaggccaata ccacgatgat
     7501 cgcgacacaa gccaacgtcc actctcccat ctgagaaaag aatcgctggt aagcggcaat
     7561 tgccataccg ctaatttgcg actctgtcgt ctgctgtgcc acgacgcctg ccagccagtt
     7621 ggcgaccgcg cctgttgcca gcatataaat accggttaat acgccagaca ttttcagacg
     7681 cgtgatttgc gcaatcgcca ccgggtcaat aaagagttca gcaaagccca ttagcgccag
     7741 cccggatatc atcacgccca ttgacgcttg accgccagcc gctgcatgtc gggcatcaaa
     7801 tgccagcaac ataaagccac aagccatcag cagtaagcca aaggcaaact tcagccagac
     7861 gcgcaatgct gaattgccgc ggctttctgg cgacgccagc caggccagaa caaccccagc
     7921 gagcatcacc gcaatagcat tcaccgactg gaatagtgct gtaggtactt caatattgaa
     7981 tgcctgacga ttcacaaagc gatcgataaa caagctgatg gtactgccgc cctgttgtgc
     8041 cagtacccag aacaacgtcc cgacaaacat caacaataca atttgccaaa gagcacggcg
     8101 gtgttcgggg aatttgatca tcatgcgggc aatgatttgt gctgcaatga ggcaaacgat
     8161 cgccagcaaa tatccggacc agtcgttctc cagcagcagg gtaaaaaata ctggggctaa
     8221 acagagcatc accactaacc agctccatac tggtaaggca aatttgacgc tagtgagcgc
     8281 ttttttatcc atactacgcg tggactggaa atgacgatga ccacttaaga aaatcaacaa
     8341 accgataaac atgccgcctc ccgcaagggc aaagccaaca tgccatccat accactgagc
     8401 agccaggccg caggcgatgg gcgcggcgat agaaccgata ttgcccgcag catacagcag
     8461 cgaaaaaccg ccatcacgtc gatgatcgtt ctcgtcgtag agctcgccaa gcaaacagct
     8521 gatgtttgat ttgaataaac cgtagccaca aataatgatt gccagcgcca gatacaggct
     8581 aaaggttgaa tttgtatcaa tgcccagcac cacatggcca agggtcatta acagcgcgcc
     8641 ggcaatcact gcagtgcggt tgccgagcag gcggtcggca agccagccgc cgagaatagg
     8701 ggtaacgtaa accagagaag catatgcgct gaacaggctg atggcatggt tatcatcaaa
     8761 accaagctga tgggtgagat agagaatgag taaggcacgc atgccgtaaa aactgaagta
     8821 ctcccagatt tggatcgcca cgatatagta tatcgcgcgc ggctgtgagg gtgttttcat
     8881 gtgttctcct tatgagcaaa aaagggaagt ggcaagccac ttcccttgta cgagctaatt
     8941 attttttgct ttcttctttc aataccttaa cggtatagcg gccatcagcc tgacggtatg
     9001 caccgtgaat atcggtttca aagcccggat agtgagcgcc gatttcacac agcatctgca
     9061 ggaactccag aaccggacgg ctttcttcgg tgatcatttc acccggcatt accagaggaa
     9121 ctcccggcgg atacggaagg atcatattgg cgttaatacg acctaccatt tcgtcgaggt
     9181 aaacttcttc ggtcataccg tgcagctctt tctggaacgc agcatacgga gtcattacca
     9241 tagtcggcag aacttcaaat gcgcgataca tcagatccgg cagattgtgg tgaacaatca
     9301 gtttgtggat attctgagcc agttcctgaa tacgcatgtt ttcatagaat tcaggatctt
     9361 cacgatacag agacggcagc atgtttttca cacgcaggtt cagatcgaac gcacgtttga
     9421 agtcagtcag agcacgcagc aggctcagtg ctttggtctt atcgataccg atgctgaaca
     9481 ggaacagcag gttatacgga ccggttttct caacaacgat gccatgttcg tcgaggtatt
     9541 tcgccacgat gctggccgga ataccaaagt cgctcatggt gccgtctttt tccatccccg
     9601 gagtcagcag ggtgactttg atcgggtcaa gatacatgtg ctcgttatcg atgtttttga
     9661 agccgtgcca ggtgctgtca gaacgcagcg gccagcattc agtcgtatcg atatgatccg
     9721 gctgccatac atcaaagaac cagccatcag attccgttct cagacgtttg atctctttac
     9781 ggaatttgat cgcacgttca atggaaccat tgatcagacg tttacctgca ttgcctttca
     9841 tcatcgctgc agcggtttca gtggacgcca cgataccgta gtgcggagag gtggtggtgt
     9901 gcatcatgta ggcttcgtta aaggtttctt cgtttacgtc acctttaacg tggatcatgg
     9961 aagcctgaga gaacgccgcc agcagtttgt gagtagactg ggtttcgtaa atcactttcc
    10021 cttctacacg gccaccgctc ataccgcatt taccttcgta aatcggtgag aagttggtgt
    10081 aaggcaccca cgcggagtca aagtggatgg atttcacatc cagtgttttc ttgatgaagt
    10141 cggtgttgta cagcagacca tcataggtag agttggtaat tacagcatgt accggccagg
    10201 ttgcgtttgg tgtttctttc acgcgcttag caatggtagc gtgctggaat tcactctgtg
    10261 ggataccacc aagaataccg taagcgttac gggtcgggcg gaaatagatt ggcgtaacat
    10321 cgctcatcat catcaggtgg gtcagcgatt tgtggcagtt acggtcaatc agaatggtgc
    10381 tgcctgccgg agcagagtac ataccaacaa ttttgttcgc agtggaagta ccgttggtca
    10441 ccatgtagct gcggtctgcg ttaaagacgc gagcgatata ctgttctgct tctttgtgtg
    10501 gaccactgtg atccagcaga gaacccagtt cagatactga aatggaaata tcagatttca
    10561 tggtgttcgg accaaagaaa tcatagaaca ggctacctac cgggcttttc tggaatgcag
    10621 taccgcccat gtgaccagga gtacagaaag tatatttacc ttcacgaaca tatttaaaca
    10681 gtgctttggt cagcggaggc agaatagtgt tgatatattc gtcagtggtc tgcttgatct
    10741 tgttagcaat atcatcagca gcacccagcg catattcaaa gaagctaatc tgtaaacgca
    10801 ggtcattcag gcttacatcg agagtggaat acgtattagc gaacgcgtac aacggcaggt
    10861 tctcgttcat tttgctaatt tcttcgcaca gctcgagatt atatttatcc cagtcaaaaa
    10921 taacaccgca cagacgcgca ttgttttcga tcagttttaa taagtcgtca cggtcgttcg
    10981 ggtaaacaat ctggaagttc agacgttcaa gcgcgcgatg aagttcacgg atgggttctt
    11041 ctttaaaata aacccccatg tgattcaata ttgcaataac gttcatagtc atatctccag
    11101 gtaaaaaagg cccctcccaa cacatgggac aaaatgaaag gaggagcctc ggaaaatact
    11161 tttaattaat gtgcgttaga cgctgtgtgg ttatccattg agtggctctg gcgctcgtgc
    11221 attttgcgag cgtagaacat caggataatc aggctgacga tgaaggtacc tgccagctcg
    11281 aaggagcttg cgcccatcag cgcgatgaag cagaacacgc aacccagtac agagcagatc
    11341 aggctgacaa agttgcggat gttaacgcct tcaaaacgaa tcaggtcaac gcaagagtag
    11401 aagtacggca gcatagtcag cagtactgcg ataccggtca gttcaccgaa caggtcagag
    11461 gctttaccac cggcagagtt catcagagtg atgaggatca tcagggcagt cattttcact
    11521 gcagccagca gcagaccttt tttcggaata ccgttgctgt cgacttcacc ataaactttc
    11581 gggaagttac cgtcgttagc ggcacgtaca cctgcctggc ctaccaacat catccaggag
    11641 cccagagaag tcagacacgc aaaggcggtg aatgcagaaa ccagtggcgc agcccagtta
    11701 ccgaggatag ttgaagcact gattgcaaac ggagcaccgg aagccgccat tacagaagac
    11761 ggatacatac cggaaagcac ctgagtcgca gcgatgtaaa caatacctgc taaaccagta
    11821 cccagcatgg ttgccagcgg aacggtacgt ttcgggtttt taaccatacc agtacttact
    11881 gctgcggatt caacacccac gaaggcccac aggcagagca gaatactttt aatgatcgca
    11941 tgaccatcag tggtatccgc agtattccag ttagctgcat aagttgctgc atcaaaccaa
    12001 tgccagccaa caatagcagt catcaccaca ggaataagaa ccagcaccag accaatagtg
    12061 gttaaacggc ttacccaggt accgccgagc atatttacaa aggtaaatac ccagacgata
    12121 gcaatacagg cgatacccgc cggaacagga tcatttaata ctgggaagaa ggtggaaaga
    12181 taagatacag cggtaatacc aattgccagg ttaccaatcc agttagcatg gtaataaaga
    12241 acacctgtct gaaaaccaaa tgcaggggaa atttctccgg catacgcaat tgggccacct
    12301 tgttgcgggt tttttgttgc cagtcgggca tatacatatg ccagcgacat tgcaccaata
    12361 atagagataa tccaacccca gatagcaata ccaccgatac ttgctaggtt cgcaggtaat
    12421 aatgcaatac cgctccccat catattaccg gcaacaacac cggtacaggc aaatagcccg
    12481 atcttcttgg cagaactcat gctcttctcc taatttcatt tttgaatttg gagtccgggt
    12541 catgatgtat aactatttcc tgaccagacc aaactggcgc taagattact cacgaaaaaa
    12601 ggattaatcc taaagattag gtgaaataac acaaaagttt ctgtaagtga gaacttgagg
    12661 ttttttatta acacatcagg atcgcaagtt gatatcatga aaagataaac attcaatgtt
    12721 tacaatgcat tgcgtgacat tctctggtta aatttatgta ataaaaatta tgcggcaaat
    12781 aaattgccgc aacatattat accaacggga acatacaaaa actcaacaac aaatattccc
    12841 gagcatgaat caacccggga gttacttatt ctgaagcgag aaatttgtcg agataaggta
    12901 caacataagg aacagaagtc tggaatatac cattttcaat ccagtaaagg gtgtttgccc
    12961 ctgggcgtaa attaaaggcg gtgagatatg catcagctgc ttcccggttc atccccttca
    13021 tttcataaac cttgccaagc aacacataat ttagccagga catttcaaga tcaatgccgg
    13081 tatttatcgc ctgataagac tcatctgttt taccttttac cagggcactg accgctttta
    13141 tttgatatat aatggacagg ttgttcaatt ccggcagtgt aacaatgtta tctatttctg
    13201 tgttcagtgc tgctaattgt ttttcgtcta aaggatgttg agaatggcgc acgatatcaa
    13261 ctaatgcttt ttctgctctc gcgtaggtaa attctgggga tgattgaaca atctcaccta
    13321 ataattcact ggcacgatcc aatgatttat catcaccatg cagtaaataa tcatgtgcct
    13381 gataaaaatt agttaataac gcaccacgat gcggcaaaat ttgctggagc atctcctgca
    13441 ttcgttgtgg ccacggttgg tttaacgctt ttgataaact ctggagcaaa tcattttgaa
    13501 tcgccagctg attaccgtta gtgatgacat aacgtttatc cagcatggtt gaaccatctg
    13561 cattgtctac caattttacc gacataaagc attgttgagc acggtattgg cgctgattaa
    13621 caaacgcaat agataatgtt ttaccggaac tgctcggttc atcaatgttg tagttgattt
    13681 tgtcatgcac cataaaggtg gagaaggtgt taagtgatgt cgccaccaaa tcacccacgc
    13741 ctatcgcgta agagagctga tacggagaac tccagctgtt acaactctta ttaaccatat
    13801 taatgtcaat atcgcgtgga ttgagcaaaa tgcgcgattt actcatagga agacgtgttt
    13861 caagacttga aaacgctacc agtgcgacac agatacctaa cgacaacagg aaaaaaaacc
    13921 atacccaaaa ggtagtgaat cgtttgcttt taactgggga ttgttcaggt ggcgttgtgg
    13981 tgttttgaat gttaagactg tgggagggag aatctgtggc aggaaccgcc tctggtatag
    14041 ggggaggcga agatagcatt atttcctctc cctcttcttc gctgtaccag ataaccggca
    14101 ccattaattt atagccgcgc tttggtacag tagcgatata gacaggacta tcttcatcat
    14161 tatcttttaa tgacttacgt agttctgaga tactctgcgt cacaacgtga ttggtgacaa
    14221 tacttctctt ccagacatta tcgataagtt catctctgct aagtacttcg ccactgtgtt
    14281 gagcaaagaa aaccagaaga tcgattaatc tcggctcaag ggtaagttga cgcccattgc
    14341 ggctaatttg gtttatggac ggagtaacaa gccattcgcc aacgcgaact acaggttgtt
    14401 gcataataga aactcattcg aaaagggaat gatgcaatga taattgccat aacctatttt
    14461 ttccatctat agatgggttt atttacatat tattggtgaa tgcaagacgt tatttttact
    14521 cgccataaac ttcttgatta catagtatta cgaaaggatt ttactgagaa ccagaagtaa
    14581 ttttccttac catcaaaatt catcatcttt gccaaagaaa aatgttcaga aaataatcca
    14641 tgaaaaattg tccggagcgc ttactatttt aatggattgt tagtctttgc atgagcaaac
    14701 ggactgatac atttctcttt gttctcattc agaaaatctc atcagttggc gttctgcccg
    14761 atgttgtgct ttatggatgc attacgctcc tgatgacgtc atttgacgtt caacagcatc
    14821 acggggccgc acgacatttc acgtcagtca gcgctatagc tcagaaacaa attttcccga
    14881 attgggatat gcccgcaaat tgctggtgat gtggggagaa tctggttgag ttcggtagaa
    14941 ttgatttggc ggcaggacgc ttaaatcgtg gcgtcctgaa acgaaaaatg gacctccgtg
    15001 gaggtccgtt tatatgaatt tggtgcccgg actcggaatc gaaccaagga cacggggatt
    15061 ttcaatcccc tgctctaccg actgagctat ccgggcaacg gggcgcatta aaccgtaatc
    15121 tgcacatctc gtcaacctaa tttcagtaaa agcgattcaa ctgcttaaga ttgcggcaaa
    15181 tcgcttcttt tctgtgtttc tgtcaggtca gtgcaccacc ctgacggcag cgggcgaagc
    15241 gcaggatatc ttccgccagc cgatgtgcgg tgtcgacatc cgcctggcta cgattcacca
    15301 gcattcggct taaacagcct tccagcacca gttccatctg ctttgctacc atcgccggat
    15361 cgtcaacttc cagcgtggtt aacagttcgt gggtgaaatc gtaggccgcg cttttttgct
    15421 gatcggccag ttgatgaata gggtggccag gatcgggata aaacgtacag gcagcgataa
    15481 acagacagcc cggatagcgg ttgtttttaa cgcactccga taacgcctga taacgtgcca
    15541 gcaacttttg ttcggcggtt tgcgtttcgt ccagcatcag ctgacgacgc cagacatcta
    15601 tctgttggct aagataacgc agcgcatcgt agaggattgc ctctttgtct ggccagaagc
    15661 ggcgtagctc gtccagtgga taatccacac gttcagcaac catctccagc gtggtgttgg
    15721 caatcccttg taattctaat aatttcaggg cttctcccag tacatcttca cgttgcacgc
    15781 tattttcctc cgtctttccc actgcaagtg tcgttcacgg ttggcgatcg cgcaaatgtg
    15841 cgctgaaggt ttcagcatcc ataaagcccg tgacgcgtgc ttgtggatgc tcctggcctt
    15901 gtccgtcaaa aaagagaatt gtcggtaggc caaggacatt aagatgcttt aacagcgcca
    15961 catcttgtgc gtcgttggca gtgacgttgg cctgaagtaa gaccgtatct gctaacgctt
    16021 tttgcacctg cgagtcgctg aaggtgtatt tctcaaactc tttacaggcg acgcaccagt
    16081 cggcatagag atctaacatc actggtttgc ctttggcttc aacgagcgcc tgatttaact
    16141 catctaccgt tttgatttgt gtaaagttga gatgcgtctg agtttgcgcg gtatgtgttg
    16201 caccaaatgc ccaatcctga agtgggcgta cgctaaccaa tgccgctgcc agcaggatta
    16261 tttgcaccac gcgcatccag ccgcgtttgg cctgtaggct ggtgataaag gcccagccaa
    16321 agaatgcgac accaagcgcc gaccacaagc gtaatcccca tatatcacca atcactcgct
    16381 ccagcaggaa gaccggcagt gcgaggatca caaaaccaaa cgcggttttg acttgttcca
    16441 tccacgggcc gcttttcggc agcaagcggt taccaaagac ggtaattagc atcagcggca
    16501 ggcccatgcc cagcgcataa agataaagcg tgccgccgcc cagccacatg ttcccgcttt
    16561 gggcgatata cagcagaatc gcgctaagcg gtgcagtggt gcatggtgaa cagatcagtc
    16621 cggcaatcgc ccccataata aacacaccgc caggtgagcc gccctgttgg cgattgctca
    16681 tcagcgtgag acgtgtttgc agcgaagagg ggagttgcag agtaaacaag ccaaacattg
    16741 acatcgccag caaggtaaag acgatggcga ggccaatgag cacgtatggg tgctgtagcg
    16801 ccgcctggaa ctgtaaccct gcggcggcaa ccaccagacc cagcgccgtg taagtcagcg
    16861 ccatcccctg cacataaata aaggtcagca acaatgctct ggcagtggaa agccgctgtt
    16921 taccgcccag cacgatgcca gaaatcagtg ggtacattgg cagcacgcat ggcgtaaagg
    16981 cgataccaat accgatcaac aacgcccaga gcgcggaaaa gggcaattgc gcggtgggct
    17041 gctcttgctg cggaacagac acaggctgtg acgcttcgtt gttggcgacc acttcgctta
    17101 acggaacggt tttggtttct ggcggataac agaaaccggc atcagcacag ccctggtagg
    17161 tgacagttaa cgttgctccc gcacttgcct ggttgatggt tacgggaagc gtcagccgat
    17221 cgcggtaaat ctcgcttttg ccgtaaaact catcttcatg ccagacgcct tgcggcagct
    17281 gcacgtcagc aattttcgcg tgttccggcg taatgcggat ctgtttacgg tagaggtagt
    17341 aaccgtcttt gatctgccag gtcagattaa ggtcatgttg gttttgctga aaatcaaaag
    17401 caaaggcttg atccgcgggg acaaattgtg aacgtcccgg cgcgtcgaat aatccggcaa
    17461 aaacggaagt gctgcaaagt agcaggatca gcgtaaagat gcgttgagcc atgagaggta
    17521 atctgtgtct ccgtgtgtaa caggtaaaac cagaagttcc ggggtttgat atggatgatg
    17581 agacttcagg cattccagca gtgcctgctg gtgagatacg gtagttttta aaatcatctg
    17641 cacttcgtat tcttgctcca gcttaccttc ccagtaatag agagaggtag cgccggggat
    17701 caaggtcgcg caggccgcca gtttttccgc cagcactttg gcggctaaat cctgggctgt
    17761 cgcttcatcc ggtgccgtac atagcaccac gacagacgtg gtattcgaac ttttttcatc
    17821 aagcataaac acctcgcaag aacagatgga actgcaagag agaggtcact atacaacgga
    17881 cggggaaagg atgttagtcg gcgggaaaga aagcggggcg tgaacgcccc gcgatgggtc
    17941 attacagcat gaagctaccc agcacgaagc cgaagcaaac ggccagggca acacccagag
    18001 tacccgggat gaagaacgga tggttgaaga cgaatttacc gatacgggta gtacccgtgt
    18061 catccatctg taccgcagca accagcgtcg ggtaggtcgg cagaatgaac agaccagaca
    18121 ccgcagcaaa agaagcaaca gcggtcagcg gagaaacgtt cagtgccaga gccatcggca
    18181 tcagtgcttt tgcggttgca gcctgagagt acagcagagc agaagcaaag aagaagatga
    18241 cggccagcag ccacggatga ccctgaatca cttcaccagc ggtatctttg atccagtcga
    18301 tgttgttgga aacgaaagta tcgcccagcc acgcaacacc caggatacaa atacaggcgc
    18361 tcatacctgc tttgaaggtg ctggagttga gaatgttgtc ggtatcgact ttacagataa
    18421 cggtggtcag agttgcaacg ctgagcatga tgatcaggat tgcgttggtg gtgttcatca
    18481 gtggtttttc aaccagaccc atgcttgggc tgttgatgat tgcatagata accacgccaa
    18541 ctacgcccag caggaacagc cagacggacg tttttgcacc ggatttgatt tcaatctgct
    18601 tttcaccgcg cagttcaacc aggccctctt ccagacgctt gcgataaatc ggatcgtcag
    18661 agagtttgga gttgaacagc atagtgacca ggaaggacat caccagaacc gccagcaggg
    18721 tggacgggat gaccacggag agcagatgga ggtagctgat gccatgacct tccatcacgg
    18781 aagacatgta aaccactgcc gctgagattg gcgatgcggt gatcgcaatc tgcgcggata
    18841 ccactgcagt agacagcgga cggcaaggtt taacgccttg ttccttcgca acttcagcga
    18901 taactggcag tgtcgccaga gagatgttgc cagtaccagc aaagatagtc aggaaatagg
    18961 tcacgatcgg tgcgaggatc gtgatgtatt tcgggttacg gcgcagcagc ttttctgtct
    19021 gatgaaccag atagtccaga ccgccagcaa cctgcatggc agaaatagcg gcgataaccg
    19081 ccatgataat ggaaatgaca tcgaacggga tgttaccggg tttaacgcca atagcggcaa
    19141 gaaccagcac ccccaatccg cctgcaaaac caatacctat tccccccaat ctggcgccca
    19201 agaagatcgc cagcaaaact atgatgagtt ctacaactag catattagcc ttccttgttt
    19261 tttaacaagt tgatattaaa ttgttatttt taagttactg ctcacaagaa aaaaggcacg
    19321 ccatctgacg tgccttcttt atttgtacta ccctgtacga ttactgttcg ctttcatcag
    19381 tatagcgttt tgctttgtaa gccgggttca tcagattctg tacggagaaa atatcgtcaa
    19441 gttccgcttc agtcaacaga ccgcgttcca gaacgacttc acgtacactc ttaccggttt
    19501 cggcacagat tttacccacg atgtcaccgt tgtggtgacc gatgaacggg ttcaggtaag
    19561 taacgatacc gatagagttg taaacgtaac cttcgcacac ttctttgtta gcagtgatgc
    19621 cgttaatgca tttttccagc aggttgtagc aagcgttggt cagaatgtga acggattcga
    19681 acatggcctg gccaatgact ggctccataa cgttcaactg cagctgacct gcttctgctg
    19741 ccatggtaac agtggtgtcg ttaccgatga ctttgaagca tacctggtta accacttccg
    19801 gaacaaccgg gtttacttta gctggcatga tggaagagcc tgcctgcagt tccggcaggt
    19861 tgatctcgtt caggccggca cgtggaccag aagagagcaa gcgcaggtcg ttacagattt
    19921 tggacatctt cacagccagg cgtttcagcg cgccgtgaac cataacataa gcgccgcagt
    19981 cggaggtcgc ttcgatcagg tcttcagccg gtacgcatgg gaagccagtg acttcagcca
    20041 gttttttcac tgccagcgga gagtactctt tcggcgtgtt cagaccagta ccgattgctg
    20101 ttgcgccaag gttaacttcc agcagcagtt cagcggtacg ttggatgttt ttcacttctt
    20161 ctttcagcag gatgctgaaa gcgcggaatt cctgaccgag ggtcatcggt actgcgtcct
    20221 gcagctgggt acgacccatt ttcaggatgt cctggaattc gacagcttta cgttcaaagc
    20281 cttcacgcag ttggttaatc gcatctacca gtttaatcag ggaagagtaa actgcgatac
    20341 ggaaaccggt cgggtaggcg tcgttagtag actgacattt gttaacatgg tcgttcgggt
    20401 tcaggtactg atattcacct ttctggtgac ccatcagttc cagaccgata ttggccagca
    20461 cttcgttggt gttcatgttt acggaagtac ctgcgccgcc ctggtagacg tctaccggga
    20521 actgatccat gcattttccg ttgttcagga cttcatcaca tgcggcaatg atggcattcg
    20581 ctacactttt aggaatggtt tgcagctctt tgtttgccat agctgcggct tttttaacca
    20641 ttaccatacc gcgaacaaat tcaggaatat cactgatttt gttgttgctg atatagaagt
    20701 tttcaatcgc tctcagagtg tgaacaccat agtaggcatc agctggaact tccctggtac
    20761 ccaacagatc ttcttcgata cgaatgttgt ttgacatgtg aaccttcttt ttcaagctgc
    20821 caatgatttg ctttaaacac acagaatata tgtggtttcg aatgtttttc gaccgacgat
    20881 tatcccctgc atcgaccgaa tacccgagat catatgctgc ttgaggattt ctaccgtaac
    20941 ctggatcact ttaagtgtcg gtttttaccc cttaattatt aatttgtgaa atggatcacc
    21001 gctttgggat tactaccaaa aatagttgcg caaacatctt gaaattttgc taatgaccac
    21061 aatataagct aaacgcgatt cgcaacccat tcaggtagcc gggtttaacc ggctgctatt
    21121 acaggagaaa cctttgcgct ggttaccttt tattgccatt ttcctttatg tctatattga
    21181 gatttcaatc tttattcagg ttgctcatgt attgggggta ttgctgaccc tcgtgctggt
    21241 tatattcacg tcagttatcg gtatgtcact ggtacgtaac cagggcttta agaatttcgt
    21301 gctgatgcag caaaaaatgg cggcgggtga aaacccagcg gcggagatga ttaaaagtgt
    21361 ttcgctgatc attgccggtt tgctgctttt attaccgggc tttttcaccg acttcctcgg
    21421 tcttctgctt ttattgccgc cggtgcaaaa gcatctgaca gtgaagttga tgccgcattt
    21481 gcgcttttct cgcatgccag gcggcggttt tagcgccggg accggtggcg gtaatacttt
    21541 tgatggtgag taccagcgaa aggatgatga ccgcgaccgc cttgatcata aagacgatcg
    21601 ccaggattaa tgtcgaaacg ccggattatg tggttatgcc attttccggc gtttttcgtt
    21661 ttggcagaaa cagccataac cccgccagca tgatcagcgc gtagagactt ttccagccga
    21721 ccattgccag taacagaacg cataatagcc cgccaaccac cgccagtagt cgataacgtc
    21781 cttgcaataa tttacagcct gccagcatgc ataacagata aatcataata aagatgccat
    21841 tggcataaat aataagagcg tccagattga tctctaaagc atgaatcacc aacgtgctta
    21901 ccacgcagca gccgagcacc gcattgaggg cattattcgg gatatggcga gaagagaggc
    21961 gtgccaggta gtggtcagga ttatgttgcg cctgcgacca gaccaggcgg gcgaagctct
    22021 gtatataaat gttgagactg gcaaagcagg ccagatagcc aattacgcag gcaatccata
    22081 acgctcctac accgaacaac tgcactacaa ttttgggaag cgatgctgcc gccgccattt
    22141 gttcaccata ggcgtcgaag tgtaagacga ctaccgtaca gccccaatag actaatcctg
    22201 ccagcagcag gccaatcatc aaagcacgag gaaaatcacg ctctggattt ttaaattccg
    22261 aggcaagatg ggcaaatgct tccagaccga caaaacacca gaacatcact gataacgcag
    22321 caaataaccc ggtaagttcg atatttcctg gcgcagggaa ggggatattc gcaggtttga
    22381 tatcgcccgc ccaccagata gcgacaatca gtgcgacgat aagtccggca ataactgttt
    22441 gtagattagc actggaactg gcaccgcgag taccgatata ccacaccagc gccagcgtac
    22501 cgagttctgc caacaacagt tgccagctat gccagccaaa cattgcctga ccgaatccgg
    22561 cagcaatttg tagcgcggca ggcaaaccca cgggaatgac cgataaaaac aaccagccgg
    22621 tgactcgctc aagccgcgaa ccaaacgcca taccgacgaa gtgcgcgacg ccgcctgcgc
    22681 tgggatagtg gcgacccaga atcgcaaaca caatcgcaat cgggaacact aagataatca
    22741 aaacgggcca cgcccacagg ctgttattgc ctgctactag cgcagctaac gcaggaacgg
    22801 caaacacgcc agtgcctaat aatgacgtcg atagcaggcc gatgccctgg gccagcccca
    22861 gttcttgttt gagtccactc atgggttgat gtccgattgc gcccaaattt tgggcaactg
    22921 cgtagatttt cgatggtagc acaatcagat ttgcttatga cggtgatgaa gaaatagcga
    22981 tgaaatgtga ggtgaatcag ggttttcacc cgattttgtg ctgatcagaa ttttttttct
    23041 ttttccccct tgaaggggcg aagcctcatc cccatttctc tggtcaccag ccgggaaacc
    23101 acgtaagctc cggcgtcacc cataacagat acggactttc tcaaaggaga gttatcaatg
    23161 aatattcgtc cattgcatga tcgcgtgatc gtcaagcgta aagaagttga aactaaatct
    23221 gctggcggca tcgttctgac cggctctgca gcggctaaat ccacccgcgg cgaagtgctg
    23281 gctgtcggca atggccgtat ccttgaaaat ggcgaagtga agccgctgga tgtgaaagtt
    23341 ggcgacatcg ttattttcaa cgatggctac ggtgtgaaat ctgagaagat cgacaatgaa
    23401 gaagtgttga tcatgtccga aagcgacatt ctggcaattg ttgaagcgta atccgcgcac
    23461 gacactgaac atacgaattt aaggaataaa gataatggca gctaaagacg taaaattcgg
    23521 taacgacgct cgtgtgaaaa tgctgcgcgg cgtaaacgta ctggcagatg cagtgaaagt
    23581 taccctcggt cctaaaggcc gtaacgtagt tctggataaa tctttcggtg caccgaccat
    23641 caccaaagat ggtgtttccg ttgctcgtga aatcgaactg gaagacaagt tcgaaaatat
    23701 gggtgcgcag atggtgaaag aagttgcctc taaagcgaat gacgctgcag gcgacggtac
    23761 caccactgca accgtactgg ctcaggctat catcactgag ggtctgaaag ctgttgctgc
    23821 gggcatgaac ccgatggacc tgaaacgtgg tatcgacaaa gctgttaccg ctgcagttga
    23881 agaactgaaa gcgctgtccg taccgtgctc tgactctaaa gcgattgctc aggttggtac
    23941 catctctgct aactccgacg aaaccgtagg taaactgatc gctgaagcga tggacaaagt
    24001 cggtaaagaa ggcgttatca ccgttgaaga cggtaccggt ctgcaggacg aactggacgt
    24061 ggttgaaggt atgcagttcg accgtggcta cttgtctcct tacttcatca acaagccgga
    24121 aactggcgca gtagaactgg aaagcccgtt catcctgctg gctgacaaga aaatctccaa
    24181 catccgcgaa atgctgccgg ttctggaagc tgttgccaaa gcaggtaaac cgctgctgat
    24241 catcgctgaa gatgttgaag gcgaagcact ggcaactctg gttgttaaca ccatgcgtgg
    24301 catcgtgaaa gttgctgcgg ttaaagctcc gggcttcggc gatcgtcgta aagctatgct
    24361 gcaggatatc gcaaccctga ctggcggtac cgtaatctct gaagagatcg gtatggagct
    24421 ggaaaaagca accctggaag acctgggtca ggctaaacgt gttgtgatca acaaagacac
    24481 caccaccatc atcgatggcg tgggtgaaga agctgcaatc cagggccgtg ttgctcagat
    24541 ccgtcagcag attgaagaag caacttctga ctacgaccgt gaaaaactgc aggagcgcgt
    24601 agcgaaactg gcaggcggcg ttgcagttat caaagttggt gctgctaccg aagttgaaat
    24661 gaaagagaaa aaagcacgcg ttgaagacgc cctgcacgcg acccgtgctg cggtagaaga
    24721 aggcgtggtt gctggtggtg gtgttgcgct gatccgcgta gcgtctaaac tggctgacct
    24781 gcgtggtcag aacgaagacc agaacgtggg tatcaaagtt gcactgcgtg caatggaagc
    24841 tccgctgcgt cagatcgtcc tgaactgcgg cgaagaaccg tctgttgttg ctaacaccgt
    24901 taaaggcggc gacggcaact acggttacaa cgcagcaact gaagaatacg gcaacatgat
    24961 cgatatgggt atcctggatc caaccaaagt aacccgttct gctctgcagt acgcggcttc
    25021 tgtggctggc ctgatgatca ccaccgagtg catggttacc gacctgccga aaaacgatgc
    25081 agctgactta ggcgctgctg gcggtatggg cggcatgggt ggcatgggcg gcatgatgta
    25141 attgccctgc acctcgcaga aataaacaaa cccccgggca gaaatgtctg ggggtttttc
    25201 ttttggtcat ctttctagta taagattcag acacggacga cgcgagtggc gtccagctca
    25261 ttgattatgg ggaataacat gcacgtaaaa tacttagcag ggattgtcgg tgccgcgcta
    25321 ctgatggcgg gttgtagctc cagcaacgaa ttgagtgctg ccggtcagag tgtacgcatt
    25381 gtggacgagc aaccaggtgc agagtgccag ctgattggta ctgcaacagg taagcaaagc
    25441 aactggcttt ccgggcaaca cggagaagaa ggcggttcta tgcgcggcgc agcaaacgat
    25501 ctgcgcaacc aggcggctgc aatgggcggt aacgtgattt atggcatcag cagcccgtcg
    25561 cagggaatgt tgtccagttt tgtcccgacg gatagccaga ttatcggtca ggtttataag
    25621 tgcccgaact gatgtgatcc agaggctgga tacttccagc ctcgtagtaa aacagataag
    25681 attatttcgc ctgtggtgca gttttgctgg tggattgaac acgtaagtga tgcagcgcgc
    25741 gtaagcattg atcctgggtt agcggttggg cgttatttgc cgctacggtg cgaacataga
    25801 cctgacatgg cacacccgcg agttttttca gtcgggggct gaaatcaagc attcggcgag
    25861 tgatcgcctc cacttcttta cccggcgttg cttcacgcgt tttcaccact gcgccgctaa
    25921 attgttcttt gccactttca tctttaaagc ggtaaagcac cgccagataa tggttgaaca
    25981 agttatgttt ccattccggt tgggaatagg tgtcatattc cagattacca tcatcctggc
    26041 agtcgacatc atataacggc aggaaatcta acagtgaggt aatacgtaat gccagttcac
    26101 gcatttccgc attattaatt gcatgaatga ttgctcgcgc cagcatttca atctgcaact
    26161 cattgacgac taactcacat ttgctaccgt catgtagtgt taatacgaag gtaagatttt
    26221 cgccctgatc atcggtaagt tccagcgtgt taacccgacg attaatatcg gcatttttaa
    26281 gctcatcaac cagaatttct gggatatttt ctgccatttt cttaatgact ttatcgcgag
    26341 cttgttcata ctgaaggcgt gcagcagcat ccagtttatg cttttgatgc agacgacttt
    26401 ccagcgcaat cagaaggtcg cgcaattcca tggcagacat aaagaacaac gattctttat
    26461 tgcgaggttc tttaattttc agcgccagtg caatgaaatt attactcttg cgaataacac
    26521 cggtattaac acccttgatg cttatggcca tgtaggttct ccctaaccat ttctcaatta
    26581 aataattaat tttagtttat aagccagata aatgggcttg gtagtaatag ttgttaaaat
    26641 aacataaata gccgtgctca ctctatataa acagaaaaga aaggttaatt attggtgtcg
    26701 gttatataaa tagtaataac agcaatgtat atgaataatt aaaggttatg caacgggcaa
    26761 agattaaact tccctgttta atcagttact gctggcgtag ctggagatcc agcggtgttt
    26821 tgctgggttc gccgccaatt tctcgcgcca gtttaggcac cagatatccc gacaccagtg
    26881 tcagcaactc acgcataatc tgccgtgctt cgtcatcact caccataaaa tgcgccgcgc
    26941 cctgtacttt atcgagcaca tgcaggtaat acggcatcac acccgcatcg aacaacgcat
    27001 tactcaggtt tgccagcgtt tgcgcgttat cgttcacacc acgtaacaga acgctctggt
    27061 tcagcaaagt aacgcctacc cggcgcaact tagccatcgc ctgacggaat gtttcatcta
    27121 cctcattggc atggttaatg tgattcacca gcaagatttg cagcgtagaa tgagaaaagc
    27181 gttcaaccag cgcatctgtg atgcgtgccg ggatcacaat cggcagacgg ctgtgaatcc
    27241 gcagacgttt gatatgcggg atggcttcca gttgtgtgag caaccagtcc agctcgtgat
    27301 ctttcgccat cagcggatcg ccgccggaga aaatcatctc gtccagttcc ggatgcgcag
    27361 caacatactc aagtgcagtc tgccagttac gcttgttgcc ctgattttcg gcatagggga
    27421 agtggcgacg gaagcaatag cggcaattta ccgcgcagcc gcctttgacc agcaaaagcg
    27481 cccggttgtg gtatttatgc aacaaacctg gcactacgct gtgctgttct tccagcgggt
    27541 cggtggagaa tccgggcgcg acaacaaact catcttgcga ggtaattacc tgacgcaaaa
    27601 gcggatcgtt cggattgcct ttctccatgc gatcgataaa tgagcggggc acacgcaggg
    27661 caaacagctt tttggcgctg cgtccggcca acagtttttc gtccgcgtct atattcaaaa
    27721 gacgcagaag ttcatcagga tcggtcacaa catcggcaag ttgcgttaac caatcttctc
    27781 tggatggggt atttagggtt acaatatgcg ccattttgtg gcttagctac caattaacaa
    27841 atttcagagg gccttatggc aacgtactat agcaacgatt ttcgtgctgg tcttaaaatc
    27901 atgttagacg gcgaacctta cgcggttgaa gcgagtgaat tcgtaaaacc gggtaaaggc
    27961 caggcatttg ctcgcgttaa actgcgtcgt ctgctgaccg gtactcgcgt agaaaaaacc
    28021 ttcaaatcta ctgattccgc tgaaggtgct gatgttgtcg atatgaacct gacttacctg
    28081 tacaacgacg gtgagttctg gcacttcatg aacaacgaaa ctttcgagca gctgtctgct
    28141 gatgcaaaag caattggcga caacgccaaa tggttgctgg atcaggcaga gtgtatcgta
    28201 actctgtgga atggtcagcc gatctccgtt actccgccga acttcgttga actggaaatc
    28261 gtggataccg atccgggcct gaaaggtgat accgcaggta ctggcggcaa accggctacc
    28321 ctgtctactg gcgctgtggt taaagttccg ctgtttgtac aaatcggcga agtcatcaaa
    28381 gtggataccc gctctggtga atacgtctct cgcgtgaagt aatgcggttg tggtgcggcc
    28441 tgcaggctgc accatcactt attcaggtta gagatgatga aacgccttat cgttcttgtt
    28501 ttgcttgcca gcacgctgct tacgggctgt aacaccgctc gaggtttcgg cgaagatatc
    28561 aaacacctcg gcaactccat ctcccgcgct gccagctaat ttttcttctc ttccgaaaaa
    28621 tcatcagatt tccgtcattt ttggcgatgt tgtctattat taatttgcta taggcaaaca
    28681 taaataacat tacctaaaag gaagacgtta tggtgaagaa gacaattgca gcgatctttt
    28741 ctgttctggt gctttcaaca gtattaactg cctgcaacac cacgcgtggc gttggtgaag
    28801 acatttctga tggcggtaac gcgatttctg gcgcagcaac gaaagcgcag caataagcaa
    28861 taacggtacg acagctgtgt cgtgccgttt gttttttctg cgatagttac ataggtaata
    28921 gttgaaattc ccctgccacc tggcaaaata tccgttcaac catcagcttt gcaggacgac
    28981 ctgcaaacgc gtcttttcac cggggacggc cccaattttc cggagcctga tatgtcctgg
    29041 attatcttag ttattgctgg tctgctggaa gtggtatggg ccgttggcct gaaatatacc
    29101 cacggcttta gtcgtttgac gccaagtgtt attaccgtga cggcgatgat tgtcagtatg
    29161 gcgctacttg cctgggcgat gaaatcgtta ccagtaggga cggcttatgc cgtgtggacg
    29221 ggtattggcg cagtcggcgc ggccatcacc ggcattgtgt tgctcggtga gtccgctaac
    29281 ccgatgcgtc tggcgagtct ggcgttaatc gtattgggga ttattggtct gaaactcagc
    29341 actcattaac taccgggctg ctgtacccaa ataaacttac tgacatcaaa cccttcccgg
    29401 gtcgcgactg ccagcatctc ctgtttcact tcgtcagaaa tggttggcgt gcgggagagt
    29461 atccacaggt agtcgcggtc cgggccgcaa accagcgcat ggcggtattc ccgatcgagt
    29521 gcaataacgt tataaccgcc atagaaagga ccaaagaatg acactttcag cgcagcgcga
    29581 gttggtgcgc cggtaaagta cgctttccct tcactctgct gccacatttc tctgtcaggg
    29641 ttatagcctt tattaatgac attcaggccg ccgtcatcac gcaggctgta tgttgcggtg
    29701 actttttcca gtccacgttc aaagcggtga tcaaaacggg caatctcata ccaggtgccg
    29761 agatagcgtt tagcgtcgaa attattcact acggtcacgc cacgcggcgg tgtaggagaa
    29821 ctgcaggcaa cgaccagaaa tgcagctgtc gctgcggcaa cgagagggag caggcgcata
    29881 aatgtttcct tactggtttt tttctaagtg tagatgacag caaggaaaag cggagaaaag
    29941 gtccgaaaat tcggacccga tgaaatttta ctgtagagtg ttgagaatct gccaggcggc
    30001 ggtaactctc gctggattgg gatagttttt gttagccagc atcacgatac ccagctcttt
    30061 ttctggaata aacgcgacat agctaccaaa tccgccggtc gcccccgttt tatgtaccca
    30121 tgatgcgcgt actgcaggag ttgggggcgt aatcggtttt acggggcgtg ctgccagtgc
    30181 aattttattg tcactgccgt taatgatgat gtcaggattt accggccagt ccagcatttc
    30241 ccagcccaga ccctgataca tatcgccggt ttgccagtag cgagattgtg ccagttgtat
    30301 cccttgttga agtattttct cattgatatc aaggggtttt aaattgcttt gcacccagcg
    30361 ggccatatct tcaatggtcg acttcacacc ataagcttca gcatctaacg cccctggcga
    30421 aacatgtact gccttacctt cgcgatatcc ccaggcgtag ttcttttctt ctgcggacgg
    30481 tacattaatc cacgtatgat tgagtttgag tggctggaag acacgagttt tcatcgcctg
    30541 ctcaaaactc aaaccagacg gcttcacagc cagtgcgccg aacaaaccga tactggagtt
    30601 ggcatacaga cgttgtgttc ctggagccca tgcaggctgc cagttttgat agaagcgcag
    30661 caagtcgctt gaggatttca cctcatccgg cacctgcaat ggcaggccgc cagcggtgta
    30721 ggttgcgaga tgtaatagtg tgatcccatt ccactgttta gcggtaagtt caggccagta
    30781 ttttgttgtg ggatcgctta acttgatttc ccctcgagca atagcgtcgc caccaagcac
    30841 gcccgtaaat gttttgctga ccgaacctaa ctcaaacaac gtttgctgtg tgacgggctg
    30901 ctttttggcg atgtccgcat agccccaggt aaagtaataa ggtttaccct gataaattac
    30961 cgctaccgcc ataccgggga tcctttgttg ctctataagc ggggtaattg tgcgatgcac
    31021 aatatcgttg atttgttgag gggcggcaaa tgtggagcaa gaggcggtaa ttaataaggt
    31081 gcagagcgtc gttttgaaca tagggtctgg tttccataca aaacggcccg ccataggcgg
    31141 gccggattta cattggcgat gcgttagatt gtaacgacac caatcagtgt gacaactgtc
    31201 aggatagcag ccagaccgta gaaaacccat ttacccgcag gtacgtggat tttcagatcg
    31261 tgcatcgcgt ggtgcattcg gtgtaaacca caccacagcg gcagaacgat catcaggaac
    31321 aggaatacgc gaccaatgaa gctctgcgcg aacgccagaa cgcgctcgta gctcagcgca
    31381 tcacctggaa acagccctag cggtagcaga ataccaacca gtaggatcat caccggcgca
    31441 atgatggcgc tccacatacc accggccccg aagaggcccc agaataccgg ttcatcagaa
    31501 cgctttggat ttggattaat catctcaggc tccttaccag tacagggcaa caaacaggat
    31561 tacgatggtg gcaaccacag ttaccgccca gagacttttg ataattggct ctggtcccat
    31621 tttttcgtct tttacaatga tattggccgc ttttggtgcc agctcaaacc aggttttggt
    31681 gtgcagtagg gctgccgcca gagtgatcag gttaatgatc acgataaccg ggttttgtaa
    31741 aaagtcgacg aatcccgccc aggcttccgg gccatttttc agggcaaaca gcccgaaaat
    31801 cagttcaatg ctgaaccaca cagccggaac tgccgtgcct tcgcgcagca tgtaaaagcg
    31861 ataaaacggc aattttttcc accaggtgga cgtcattggc cgtacatacg gtttacgttt
    31921 agtcgtcatg ttgcactcct tagcgtggtt tcagggtcgc gataagaaag tctttcgaac
    31981 tttctacttt gccctgctga atggccgcag ccggatcgac gtgtttcggg cagacttcgg
    32041 agcagtagcc cacgaaagta cagctccata cgccgttctg gctgttcaac tgcgccatac
    32101 gctccttctt accgtggtcg cggctatctt cgttataacg atgcgccagc gtaatggcag
    32161 ccggaccgat gaactctggg ttcaggccaa actgcgggca cgcggcgtag cacagaccac
    32221 agttgatgca accggagaac tggtgatact tcgccatctg cgccggggtc tggatgttag
    32281 taccctgatc cgcggtgcgg gagttgccga tgatgtacgg tttgatcgct tccagacttt
    32341 cgatgaagtg ggtcatatcg accaccagat cgcgttcaat cgggaagtta gctaacgctt
    32401 caaccttcat accgtcggtg taatcacgca ggaaggtttt acatgccagt tttggcacgt
    32461 tgttaaccat catgccgcag gagccacaaa tcgccatacg gcaggaccag cggtagctca
    32521 ggtccggtgc caggttgtct ttgatgtagc ccagcgcatc cagtaatgag gtagttgcgt
    32581 cataaggcac ttcatagaat gcgctatgcg gtgcggtatc gacttccggg ttatagcgca
    32641 ccacctcaat tttcaggttt ttcatctcag ccattcgcct tctccttctt attggctgct
    32701 tccgccttat cggctgcatc cgcttcgcca ccgtaaacac gtttagctgg cggcagcgta
    32761 gtaatcttca cgtcgctgta ctccaggcga gtcgtgccat cagcatcgcg gaaggcgagg
    32821 gtgtgtttga ggaagttgac gtcgtcacgc tcggtgcaac cttcgtccag acgctggtgc
    32881 gcgccgcggg actctttacg tgccattgcg gagtgcgcca tacattcagc aacgttcaga
    32941 ccgtggccca gctcaatggt gtagagcagg tcggtgttga acacgctgga agtgtcggtg
    33001 atgcgcacgc gcttgaagcg ttcctgcagc tctgccagct tgtcgatggt tttctgcatc
    33061 agttccggcg tacggtagat accgcagcct tcttccatgg ccatgcccat ttcgtcgcgg
    33121 atcttagccc agttttcgcc gccatcctgg ttaaccagat ctttcagacg ttgttcaacg
    33181 ccagctgcct gcgcttcaat tgccgcttcg ttgccattac cggcagttgc tgcacgctct
    33241 gtcgcttgtt caccggccag acgaccgaag accaccagtt ccgccagcga gttggagccc
    33301 agacggttcg caccgtgcag accaacagag gaacattcac ccacggcgaa cagaccttta
    33361 atgcgggttt cacagttctg atcggtttcg ataccgccca tggtgtagtg tgcggtcgga
    33421 cgtaccggaa tcggttcttt aaccggatcg acgccaacgt acgctttcgc cagttcgcag
    33481 atgaacggca aacgttcatg cagttttttc tcgccaaggt gacgcaggtc gagataaacc
    33541 acatcgccac gcggcgtgga gatggtgttg cctttacgcc attcgtgcca gaaggcctga
    33601 gaaactttgt cgcgtggacc cagttccata tatttgtttt tcggctcgcc cagcggagtt
    33661 tccgggccca tgccgtaatc ttgcagataa cggtagccat ttttgttgac cagaataccg
    33721 ccttcaccgc ggcagccttc ggtcatcagg ataccggaac ctggtagacc ggttgggtga
    33781 tactgaacga attccatgtc acgcagcgga acgccgtggc ttagcgccat acccataccg
    33841 tcaccggtaa cgatgccgcc gttggtgttg taacgataaa cgcgacctgc accgccggta
    33901 gccataacga ccgcgttagc acggatctgc accagcgtgc cttccatcat gttcattgct
    33961 accaggccgc gaacatgacc atcatcaact agaatatcca gcacgaaatg ttcgtcgaaa
    34021 cgctggatct gcgggaattg cagagaggtc tggaacagcg tgtgcagcat atggaagccg
    34081 gtcttatcgg cggcgaacca ggtgcgctcg attttcatgc cgccgaagcg acgtacgttg
    34141 acgctaccat ccgggcgacg gctccatggg cacccccaca gttccagttg ggtcatttcg
    34201 gttgggcagt ggtggacgaa ataatccacg acatcctgct cacacaacca gtcgccaccc
    34261 gctactgtat cgtgaaagtg atattcgaag ctgtcatgat cctgcgcgac agcggcggag
    34321 cccccttctg cagcaacggt atggctacgc atcgggtata cttttgagat tagtgcgatt
    34381 tttgcatttg gatttgcctg cgcggcagca attgcagcac gtaatcccgc gccaccggcg
    34441 cctacaatgg caagatcggc ttgaaaggtt tgcacgacat tcctccagat tgtttttatc
    34501 ccacagcccc gtacttcagg gtaagtgcct gaaagttacg gtctgcgaac gctattccac
    34561 tgctccttta taggtacaac agtatagtct gatggataag tctgaaattt gacgagatcg
    34621 atttttttag tgcgcaagag ggctaaatta tcactgaaga tgattaattt aattactaaa
    34681 ccatcagatc gtgctttttt tagtcactgc ccaccgttgt gttattcctg cgtaaaattt
    34741 gtctcgccgt cgcgttgcga gtagacttcg tgcccttgtc aaaaactgga gatttaacta
    34801 tgagcgaaac ggcatcctgg cagccgagcg catccattcc taacttatta aaacgcgcgg
    34861 cgattatggc ggagatccgt cgtttctttg ccgatcgtgg agtgctggag gtggagacgc
    34921 cttgtatgag ccaggcgacg gtaaccgata ttcatttggt cccgtttgag acacgtttcg
    34981 ttggccccgg gcattcgcag gggatgaatc tctggttaat gaccagcccg gaataccata
    35041 tgaagcgcct gctggttgcc ggttgtgggc cggtattcca gctgtgccgc agcttccgta
    35101 atgaagagat ggggcgttat cacaaccctg agttcactat gcttgagtgg tatcgaccgc
    35161 actatgatat gtaccggttg atgaacgagg tggacgatct cttgcaacag gtgctggact
    35221 gtccggcagc agaaagcctt tcttatcaac aagctttctt gcgttatctg gaaattgacc
    35281 cactctctgc cgacaaaacg caactgcggg aagtggcagc gaaactggat ttgagcaacg
    35341 ttgccgatac tgaagaagac cgcgacacgc ttctacaatt gctgtttacc tttggcgtag
    35401 agccaaatat tggcaaagaa aaaccgacct ttgtgtacca ctttccagcc agccaggcat
    35461 cactggcgca aatcagtacc gaagatcatc gggtcgctga acgctttgag gtttattata
    35521 aaggtattga gctggcgaat ggtttccatg aattgacgga tgcccgtgag cagcaacaac
    35581 gctttgaaca agataaccgt aagcgcgcgg cgcgcggttt gccgcagcac cccattgacc
    35641 agaatctgat tgaagccttg aaagtcggta tgcctgactg ttccggcgtg gcattaggtg
    35701 ttgatcgtct ggtgatgttg gcgctgggcg cggagacact ggctgaagtc atcgccttta
    35761 gcgttgaccg ggcataattc tgaaaaatta ctgaattaac agcgaagaat ggcgtgataa
    35821 gcgccattct gtagcatatg ttttcatttt tccgctaaag gccacaattt aagactggat
    35881 atttgatatc atccaggtat caattctgta ttggttttta cgctgcccgc tcaatgttgg
    35941 gcagtgcagt tcagtgggcg cgttttatac acgcgctgaa atgaaggatg gtttcatgcc
    36001 tcactcgata aaaaagatga gtctgatagg actcatattg atgatcttta cttctgtatt
    36061 tggatttgcc aatagcccat cggcttatta cttaatgggt tatagtgcga tttcctttta
    36121 tatattttct gcattgttat tctttattcc attcgcctta atgatggctg aaatgggagc
    36181 tgcttatcgc aaagaagaag gcggtatcta ttcctggatg aataatagtg tcggaccacg
    36241 ttttgccttc attggtacgt ttatgtggtt ttcctcttat atcatctgga tggtgagtac
    36301 ctccgcgaaa gtttgggtac cgttctcaac attcctctac ggtagcgaca tgacccagca
    36361 ctggcatatt gccggactgg agcctacgca ggtggttggt ctgctggcag tggcatggat
    36421 gattctggtc accgtcgttg cttcaaaagg gattaataaa attgcccgca ttactgcggt
    36481 gggcggtatt gcagtaatgt gtctgaattt agtattgctg ttagtaagca ttactatttt
    36541 gttattaaat ggtgggcatt tcgcgcagga tattaatttc cttgcatcac cgaacccagg
    36601 ttatcagtcc ggtctggcaa tgctatcgtt tgtggtattt gccatttttg cctatggcgg
    36661 aattgaagcg gttggtggtc tggttgataa aacggaaaat ccagaaaaga actttgccaa
    36721 aggtattgtt tttgccgcta ttgttatttc aatcggttat tcgctggcaa tatttttatg
    36781 gggcgtcagc acaaactggc agcaggtatt aagtaatggt tccgttaacc tcggcaatat
    36841 tacctatgtg ctgatgaaga gcctcggggt gacgctgggt aacgcactgc atttgtcacc
    36901 tgaagcgtca ttgtcgctgg gcgtatggtt tgcgcgtatt accggactgt cgatgttcct
    36961 cgcttatacc ggtgcgttct ttacgctttg ctattcaccg ctgaaagcca tcatccaggg
    37021 gacgccgaaa gcattgtggc cggaaccgat gacgcgcctg aatgcgatgg ggatgccgtc
    37081 tatcgccatg tggatgcagt gtgggttggt tactgtcttc atcctgctgg tttcgtttgg
    37141 tggcggtacc gcatcggcgt tctttaacaa gctgacgctg atggcgaacg tgtctatgac
    37201 gcttccttac ctgttcctcg cgctggcttt cccgttcttt aaagcacgtc aggatctcga
    37261 cagaccgttt gtgattttca aaacgcgtat gtcggcaatg attgcgacag tggttgtcgt
    37321 actggtggtg acatttgcga acgtcttcac catcattcaa cctgtggttg aagccggaga
    37381 ctgggacagc acattgtgga tgattggcgg ccctgtcttc ttctcgctgt tagcgatggc
    37441 gatttaccag aactattgca gcagagtggt aaaaaatccg cagtgggtgg ctgagtaatc
    37501 aaatgcccta tcgtcggcct gacgataggg cgtaatgaca gggaattagt gagatttcgt
    37561 atgcgctata gcgaaattaa actatgggtt acctcatgag tgcgcgcatg tctgtcttgt
    37621 gctgcatctg gttcattgtg gcgttcctct ggataaccat tacctccgcg ctggacaaag
    37681 agtggatgat tgatggacgc gggattaaca acgtctgtga tgttttgatg tatctcgaag
    37741 atgacgatac tcgcgatgtc ggtgtgataa tgacgttacc gctctttttc ccttttctct
    37801 ggttcgcttt gtggcgaaaa aaacgcggct ggtttatgta cgccaccgcg ctggctattt
    37861 tcggctactg gttgtggcag ttttttctgc gctatcagtt ttgcttgtga gccggatggg
    37921 ttcatccggc cacaaagacc ttacaaactt cccgcctgac gacctttgcc cgcagaagtt
    37981 aatgttctcc ccgtttgttt accattcagg ctttccagac gcatctggaa gggcgggaat
    38041 ggcatatcga taccgtgggc gtggaagcca gccagaatca gctggtgaat ctcatggcgt
    38101 agcggcatac ggtgacccat ctcagcggcg taaatacgca gctcgaaaat ctgaatcccc
    38161 tgctgcagat ccaccaggaa gacttccggc gccgggttgt cgatcaccag cgagcagcga
    38221 cgcgctgcgg tgagcaggat ttccgtcact tcttcactgt tggcattggc aggggccgga
    38281 atcgtcaaca ccacgcgcgt gaccgagtca gagagcgacc agttgataaa ctgctcggta
    38341 ataaacgcct tgttcggcac gataatttct ttgcggtccc agtcgctgat ggtggtggcg
    38401 cgggtgttaa ttttcgtcac actaccggta agatcgcgga tcgttaccgt atcgccaatg
    38461 cgaatcggtt tttcgaacag gataatcagg ccagagataa agttggcgaa aatttcctgc
    38521 aaaccaaaac cgagaccaac accgagcgcg gcgaccagcc actgcaattt cgaccactca
    38581 ataccaatca tcgagaagcc gaccagcccg ccaattagca tcagcagata tttggtgatg
    38641 gtggtgatgg cgtagcccgt acccggcgtt aaatccaggt gctgcagaat cgccagttcc
    38701 agcagcgcgg gcaggttgcg caccagctgc gtggtgatga taaacaccag aatggcaatc
    38761 agcaccgcac cgagggtaat cggctccagg ctttctacgc cctgtaccgt ggaagtgaca
    38821 tcccacagcg aaatattttc gaggaagccg aaagcggaat ggatttctga ccacagcaca
    38881 atgaccgaaa gcagggcgat caacatcaaa attgagcgca ccagccgcaa ggattgcgca
    38941 ctgatggcat cgagatcgac ttcgctttca tcgacttcaa ttgctccttc cgggctactg
    39001 tgatgatgcg cttcctcttc gccacgcgca cgctgcgcta acatctctgc ccggcgatgc
    39061 tttgcccggt caaacgccag cctgcggcgc tggatcagca tccagcggcg gataacgtga
    39121 taaaccacca gtagcaggaa ccagatggca accgaggttt caagcctcgc taacagcgcc
    39181 tgcgccgttg ccagataacc caccgccgac gccagaatgg caaccagagg tgcgccaatc
    39241 atcatgttcc acagcatatg gttggtaatg ttgtcgccgc tgccttcttt gttgagatac
    39301 agcgggatcc cggccttttt caggctgagg gtgaccaccg ccagcgcacc gcaaatgagg
    39361 ataaagcaaa gccgtcccag cgaaccggaa aattcgcggt cgtcgaggtt atcgaacatc
    39421 atcagcgcca taatcagcgg cacaataagc ccgatgctca tcaggtagta acgcatccca
    39481 cgggaaacac gttcgcgcgg ccagccaaaa tgagcgataa acaagccgtt cgggcgagca
    39541 aaggtggcgc aaatcatcac tacccacagc agcggcacgg tggctgttac gccatcacca
    39601 atcgcgaccg ccagcggata aggccacgcc tcgcgcaagc cgtaacccag cgtcatccac
    39661 agcacaggca gcggtgacgc gacgagaatc gaccagaaaa gagtgcgtaa cgtcagccag
    39721 aagtgatcct gagtcacttt gccgactttc gccgccgaac gttcaagaaa acgggtgaaa
    39781 tagcggcgcg agtaaatact gcaaccgacc agaatcaacg cgccaaacag cggcaaaatc
    39841 gtctctttac tggtcagcat catcacactg gctttgccca actgactgaa ggtgtccagc
    39901 gaaatgagac gacgcagatc ctgggcgatt tccagcggcc aggcgatggt catcgggcgc
    39961 acgtcagagg tccagaacag atagcggtgc gtcgcttcgt tcacctcttt cagtgcatcc
    40021 tccagttgcc cgttggagac tttcagcttg gtcagctcca gcagtagcgt gtcgccaccc
    40081 tgcaacaatg agttcagcaa ctcacgctga gtgcgtagct gtgcttccag aatacggttt
    40141 tgctcagcgg tcagcggctg accgtcggcc tgatggattt gccgtagcag cggctgttta
    40201 ttaagcagat cctcataacg taaccgttgc acacgtaact gcgccatttc ggtatcaagc
    40261 tgttgtggtt ttggcatttc cggtagccgt gccacctgcg cccgcaacgc ttcgccgagc
    40321 aggttagatg atcccagcca ttgcgactgt tcacgcagcg tattcaacgc ctgccggacc
    40381 tgtaacgtct ggctggcagc ctgacgctgt tgcgaggcaa cgagatccat ccgctgcgcc
    40441 tgttgattca gtgccgccga tagttcgcgg ttaattttaa actgggcgac gatatctttt
    40501 ggcaaatcgg cgctactttc cgccagttgc tcggtacttt ccagcgcccg ttccgcttcc
    40561 agttggcgtt gactattcaa ctggttgcgt agtgcttgca aatatgcatc cagctgctgg
    40621 ctctcttttt cggccagctc tgagcgcaag cgcgctaatt cctggcggtt attggcagat
    40681 agctgcgcca gctccagttc atcaacgagc gctttcagac gtgcggagtc agactgcaac
    40741 gcgaaatttt gtgcctgatt gagcggggta ttgccggtaa gcgtccccag gcggcgctcg
    40801 atttcattca actgacggcg ggcatcggtt tgctgttgcg gcagttgatt cagggaatcg
    40861 gcaatctcgc gggcgcgctc ctgctcttgc tgggcctgac ggcttttatc cagcaactga
    40921 ctgctgatct ggagaatttc ctgattcagc gcatcgttag acattcccgg cgacacgctg
    40981 cgtggctcgt cacgcatgtt gtttaactgc gcgcgcagag tggcggaaag tttcgggtaa
    41041 ttatcaatga cttcttgata ttgcttgatg cgctcaaggg aaccttttcg ttcctcaagc
    41101 gcatttaagg cagactggag cgcctctacg acttccggct gcgcaggttt cgccgctttt
    41161 gcctgctcca gttcctgggt gatttgtttg ctatcggggg ccgtcgcggc gtacgccccc
    41221 caactgaggc accaggccat cagaaaagtg ataatcaggc gcacgtcagc gtttcctttg
    41281 atggattaga cctggtcttt tttatcgtca accaatgggc tggcgtcgtg ttctgcttcg
    41341 atctcttcag caggaagcgg ggctggttca gcatctggcg taacaaaggt ttcggtagat
    41401 actgccagcg gctggccaat tttcgtgaca gacaggctct ccagttgctc aaccaggtcc
    41461 actttacctg gtgcaaacag gttgataacg gtagagccta gtttaaagcg acccatttcc
    41521 tggcctttca gcagtgccac agaaccgtcg ttttccccgg caggccaggt ccagcgcttg
    41581 atgatgcctt cgcgcggcgg cgtaatggtg cccgcccata ccgtctcaat gctgcctaca
    41641 atcgtcgcac cgaccagaat ctgcgccatc gggccaaatt cggtatcgaa caggcagatc
    41701 acgcgttcgt tacgggcaaa cagattcggc acgttctgag ccgtgagatg gttaacggag
    41761 aagagatcgc ccggcacgta gatcatttca cgcagaatac cgttgcacgg catgtgtacg
    41821 cggtggtagt cacgtgggga gaggtaagtg gtcacaaacg taccgttacg gaagagatcc
    41881 gccatcagat agttgcctgc cagcagggct tcgaggctgt agttgtggcc tttggcttgc
    41941 aggattttat cttcttcgat tttacccaac tggctgataa cgccatcggc aggcataacc
    42001 aggacattcg gatcggtatc gattgggcgt acttcatcac gcagcggacg gacaaagaat
    42061 tcgttaaagg tgcggtagct ggcggtgtcc ggcttttgcg cctctttcat gtcgaccttg
    42121 tagtatttaa cgaacagatc gataaccagt tttgtcagcc atcctgcccg cttgcttgcg
    42181 ccccaacccg ccaggcgagt aagccatagt ttcggcagaa tgtactgtag cgaaagttta
    42241 aatgaattta acaaggtagc ctccaggcca ttgttttgtc gttcctgatc cggcctacat
    42301 gccggatcct gaaaaaaagg ggacgattct aacgacggtt agcttaattg tcagtcatcc
    42361 gtatcagaaa agtttttacg cgtttttacc tgcgccatgc tttccagaat acggtgatag
    42421 ttttcgaaac gggtttccgc gattttccct tcctcaaccg cttcccggat agcgcagccc
    42481 ggatcggtat cgtgtttgca atcgcgatat ttacacagac ctaaatagtc atggaattcg
    42541 acaaagccct gagtgatttg ttccggctcc aggtgccaga gaccaaactc acgcacacct
    42601 ggggaatcaa tcacatcacc gccgtgcggg aagtgataca gtcgtgcggc ggtcgtggtg
    42661 tgctgaccaa gccccgagtt gtcagagaca tcgttggtca ggatctcttt ttgcagaccc
    42721 agcaacgcgt tcagcaggct ggatttgcca acgccagact gcccggcaaa aatgctgatg
    42781 cgcccggtca acgcctcttc cagcggtttc agcccatcct gagtatgact ggaaaccatc
    42841 aatacgcgat aaccgatatt gcggtagata tccatctgct cgttgacgaa ctccatgcct
    42901 tcgtcgtcca gcaggtctat cttgttgagc acaataatcg gctcaatctg caaggtttcg
    42961 caggccacca ggtaacggtc gataatattg agcgacagct ccggcaaaat ggcggagaca
    43021 atgacaatct ggtcgatgtt ggcagcaata ggtttcacac cgtcgtagaa atccgggcgc
    43081 gtcaacactg aggtgcgctc atgcaccgct tccacgatcc ctttgacatt tacgccttcc
    43141 gccgccggtt tacccggacg ccagactacg cggtcgccgg tcaccaacga acggatggta
    43201 cggcgaatat tgcagcggtg aacgtcgcca tcggcggatt ccacatcagc gtgcatacca
    43261 aagcggctga tgacgatacc ttcatcaggc tcgccaaaca gattgtcgtc gtagtcgggc
    43321 ttctccttag acgttttaag acgacgctgg tgattggcgt tcacgcggcg ctgctggcct
    43381 ttggagagtt tatttttact caatcgtaca gactcctggt cgcccctgat gggcaaaaca
    43441 tctatgatac acgcaattgt ggatcaatat agtcactgtg aatgggtgga aaatagcatg
    43501 agtgccaatg aaaacaacct gatttggatc gatcttgaga tgaccggtct ggatcccgag
    43561 cgcgatcgca ttattgagat tgccacgctg gtgaccgatg ccaacctgaa tattctggca
    43621 gaagggccga ccattgcagt acatcagtcc gatgaacagc tggcgctgat ggatgactgg
    43681 aacgtgcgca cccataccgc cagcgggctg gtagagcgtg tgaaagcgag cacgatgggc
    43741 gatcgtgaag ctgaactggc aacgctcgaa ttcttaaaac agtgggtgcc tgcgggaaaa
    43801 tcgccgattt gtggtaacag catcggtcag gaccgtcgct tcctgtttaa atacatgccg
    43861 gagctggaag cctacttcca ctaccgctat ctcgatgtta gcaccctgaa agagctggcg
    43921 cgccgctgga agccggaaat tcttgacggc tttaccaagc aggggacgca tcaggcgatg
    43981 gatgatatcc gtgaatcggt ggcggagttg gcttactacc gcgagcattt tatcaagctg
    44041 taaaattttt cctggtcacg taagcgccgg aatccacttg cggcggcgtg attttgacgc
    44101 taaattgaac gccttgctga taatttcagc acttgagata aaaactcaaa aaaaattttt
    44161 taggggggtt gcagagggaa agatttctcg tataatgcgc ctcccgtaac gacgcagaaa
    44221 tgcgaaaatt acgaaagcaa aattaagtag ta
//
LOCUS       DAPOXO010000035        43821 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPOXO010000035 DAPOXO010000000
VERSION     DAPOXO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43821
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.035"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(86..3235)
                     /locus_tag="ROH59_002315"
     CDS             complement(86..3235)
                     /locus_tag="ROH59_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HDX4804791.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTNYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHNHTVDHH"
     gene            complement(3258..4451)
                     /gene="acrA"
                     /locus_tag="ROH59_002316"
     CDS             complement(3258..4451)
                     /gene="acrA"
                     /locus_tag="ROH59_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HDX4804792.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     AAYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            4593..5240
                     /gene="acrR"
                     /locus_tag="ROH59_002317"
     CDS             4593..5240
                     /gene="acrR"
                     /locus_tag="ROH59_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HDX4804793.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGGSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     gene            5368..8730
                     /gene="mscK"
                     /locus_tag="ROH59_002318"
     CDS             5368..8730
                     /gene="mscK"
                     /locus_tag="ROH59_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HDX4804794.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSALSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQVQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATQNGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VSKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQTLKDEFKSMKITVNWEKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLSGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNATEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(8769..8933)
                     /gene="rsmS"
                     /locus_tag="ROH59_002319"
     CDS             complement(8769..8933)
                     /gene="rsmS"
                     /locus_tag="ROH59_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HDX4804795.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPARTVLRALDIVKRDYEKK
                     LQSDETSQSE"
     gene            complement(8947..9474)
                     /gene="priC"
                     /locus_tag="ROH59_002320"
     CDS             complement(8947..9474)
                     /gene="priC"
                     /locus_tag="ROH59_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HDX4804796.1"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVAQFATLSARFDRHLFQTRAT
                     TLQACLDESGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREATAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRARLARATDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            9544..9921
                     /locus_tag="ROH59_002321"
     CDS             9544..9921
                     /locus_tag="ROH59_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HDX4804797.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGAKPRAILLILITFTISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            10074..10625
                     /gene="apt"
                     /locus_tag="ROH59_002322"
     CDS             10074..10625
                     /gene="apt"
                     /locus_tag="ROH59_002322"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDX4804798.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            10754..12685
                     /gene="dnaX"
                     /locus_tag="ROH59_002323"
     CDS             10754..12685
                     /gene="dnaX"
                     /locus_tag="ROH59_002323"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDX4804799.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQGVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPDPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSTFKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     misc_feature    12018..12082
                     /gene="dnaX"
                     /locus_tag="ROH59_002323"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            12738..13067
                     /locus_tag="ROH59_002324"
     CDS             12738..13067
                     /locus_tag="ROH59_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDX4804800.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            13067..13672
                     /gene="recR"
                     /locus_tag="ROH59_002325"
     CDS             13067..13672
                     /gene="recR"
                     /locus_tag="ROH59_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDX4804801.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            13782..15656
                     /gene="htpG"
                     /locus_tag="ROH59_002326"
     CDS             13782..15656
                     /gene="htpG"
                     /locus_tag="ROH59_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDX4804802.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETIISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            15837..16481
                     /gene="adk"
                     /locus_tag="ROH59_002327"
     CDS             15837..16481
                     /gene="adk"
                     /locus_tag="ROH59_002327"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDX4804803.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            16613..17575
                     /gene="hemH"
                     /locus_tag="ROH59_002328"
     CDS             16613..17575
                     /gene="hemH"
                     /locus_tag="ROH59_002328"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HDX4804804.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQYSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALEMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(17572..18531)
                     /gene="aes"
                     /locus_tag="ROH59_002329"
     CDS             complement(17572..18531)
                     /gene="aes"
                     /locus_tag="ROH59_002329"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HDX4804805.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGAIAEQRQYY
                     TLERRFWNADAPEMATRAYRVPTKYGQVKTRIFYPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVARRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSHLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            18683..19987
                     /gene="gsk"
                     /locus_tag="ROH59_002330"
     CDS             18683..19987
                     /gene="gsk"
                     /locus_tag="ROH59_002330"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HDX4804806.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            complement(20117..21793)
                     /locus_tag="ROH59_002331"
     CDS             complement(20117..21793)
                     /locus_tag="ROH59_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001582195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HDX4804807.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKSIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSVAALFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTR"
     gene            complement(22032..23252)
                     /gene="fsr"
                     /locus_tag="ROH59_002332"
     CDS             complement(22032..23252)
                     /gene="fsr"
                     /locus_tag="ROH59_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin MFS transporter"
                     /protein_id="HDX4804808.1"
                     /translation="MAMSEQTQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            23470..25122
                     /gene="ushA"
                     /locus_tag="ROH59_002333"
     CDS             23470..25122
                     /gene="ushA"
                     /locus_tag="ROH59_002333"
                     /EC_number="3.1.3.5"
                     /EC_number="3.6.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HDX4804809.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            complement(25160..25663)
                     /locus_tag="ROH59_002334"
     CDS             complement(25160..25663)
                     /locus_tag="ROH59_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804810.1"
                     /translation="MKFDHLVDVSFHNFVFNGKFDFVELGQTMAWLEQNFVEPDSKND
                     MGNGFYIWLFGNVEFHFENNKLYMIWCDYLSQIHLGKAIRFDKGILNNVAELNVTRVF
                     NMLVNEGADLQIRRQSPHTLLIHVNRSGVTLWFEADEEQPGDPQNYMLMAFGLTHRDY
                     DARFQYS"
     gene            complement(25660..26460)
                     /locus_tag="ROH59_002335"
     CDS             complement(25660..26460)
                     /locus_tag="ROH59_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804811.1"
                     /translation="MERITETLSIACADEIPDIALLRQTSREKVLHLHFASEAERYRE
                     EFGLVLKAQLDEFVVGMHSADPVIRIARLISLEEINRHQDFFEHCAKEYRKLATELIF
                     ALAEQLNVEMAENNPLVTFAPFKCNRKRKGKMGKWQYCFHGFHCTFENKKTEQNIEVP
                     LAYGFDFGDLDPYFFSGFIKSTPAWQPLPVAIYDDYHDGSRIIQQLLALGKLQKIPSP
                     IPQYTGVAAVDRSNVDIANFRSTLESRLHRCKLRWLLKHVKNSQRSER"
     gene            complement(26484..26963)
                     /gene="ybaK"
                     /locus_tag="ROH59_002336"
     CDS             complement(26484..26963)
                     /gene="ybaK"
                     /locus_tag="ROH59_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HDX4804812.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAASDLAKILDAKFADIARRD"
     gene            complement(27167..27961)
                     /locus_tag="ROH59_002337"
     CDS             complement(27167..27961)
                     /locus_tag="ROH59_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HDX4804813.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDISLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEDQLQNLQHIS
                     QEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            28094..28396
                     /locus_tag="ROH59_002338"
     CDS             28094..28396
                     /locus_tag="ROH59_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDX4804814.1"
                     /translation="MAQKKNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIIN
                     AATSHRDLRSPPGNRYEELSGKLQEYSSIRVNKQYRLIFKWVNGKAEELFLDPHNY"
     gene            28432..28773
                     /locus_tag="ROH59_002339"
     CDS             28432..28773
                     /locus_tag="ROH59_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDX4804815.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            complement(28831..31335)
                     /gene="copA"
                     /locus_tag="ROH59_002340"
     CDS             complement(28831..31335)
                     /gene="copA"
                     /locus_tag="ROH59_002340"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HDX4804816.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALI
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADIDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNDQQVDTKAIEADISA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            31597..32529
                     /gene="glsA"
                     /locus_tag="ROH59_002341"
     CDS             31597..32529
                     /gene="glsA"
                     /locus_tag="ROH59_002341"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDX4804817.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTSDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKVGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENTEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLINTIELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEEGNSVRGQKMVASVAKQLGYNVFKG"
     gene            32532..33824
                     /locus_tag="ROH59_002342"
     CDS             32532..33824
                     /locus_tag="ROH59_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX4804818.1"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPEVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKPLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGALLLSLIVAMVMKRNKTV"
     gene            33949..34356
                     /gene="cueR"
                     /locus_tag="ROH59_002343"
     CDS             33949..34356
                     /gene="cueR"
                     /locus_tag="ROH59_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HDX4804819.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIEQHIEELQSMR
                     NQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(34357..35092)
                     /locus_tag="ROH59_002344"
                     /pseudo
     CDS             complement(34357..35092)
                     /locus_tag="ROH59_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601795.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35186..35644)
                     /locus_tag="ROH59_002345"
     CDS             complement(35186..35644)
                     /locus_tag="ROH59_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDX4804820.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLLPLGWEWQGVMFAVLTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLIIRAVIA"
     gene            complement(35641..36558)
                     /locus_tag="ROH59_002346"
     CDS             complement(35641..36558)
                     /locus_tag="ROH59_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDX4804821.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLHIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            36704..37381
                     /gene="fetA"
                     /locus_tag="ROH59_002347"
     CDS             36704..37381
                     /gene="fetA"
                     /locus_tag="ROH59_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HDX4804822.1"
                     /translation="MQENSPLLQLQNVGYLAGDTKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNQQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            37368..38147
                     /gene="fetB"
                     /locus_tag="ROH59_002348"
     CDS             37368..38147
                     /gene="fetB"
                     /locus_tag="ROH59_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HDX4804823.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(38330..39184)
                     /gene="cnoX"
                     /locus_tag="ROH59_002349"
     CDS             complement(38330..39184)
                     /gene="cnoX"
                     /locus_tag="ROH59_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308582.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HDX4804824.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(39245..40054)
                     /gene="ybbO"
                     /locus_tag="ROH59_002350"
     CDS             complement(39245..40054)
                     /gene="ybbO"
                     /locus_tag="ROH59_002350"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDX4804825.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHREGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVGKVRHAFISEKPKMRYPVTLVTRAVMVLKRLLPGRVMDKILQG"
     gene            complement(40044..40667)
                     /gene="tesA"
                     /locus_tag="ROH59_002351"
     CDS             complement(40044..40667)
                     /gene="tesA"
                     /locus_tag="ROH59_002351"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HDX4804826.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPAQLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            40638..41324
                     /locus_tag="ROH59_002352"
     CDS             40638..41324
                     /locus_tag="ROH59_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4804827.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            41321..43735
                     /locus_tag="ROH59_002353"
     CDS             41321..43735
                     /locus_tag="ROH59_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804828.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQIAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGSENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSIERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLVLSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVTVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WATLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVTPLKAF
                     LAEHQIVPESFYPVVRARLTAINDKPTEGNGDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKAGEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQSKVFDFPWEPDWRLWIVLPCSGALLLSLCGGWLGARLLKGKAL
                     FRQFVG"
BASE COUNT        10531 a        11459 c        11590 g        10241 t
ORIGIN      
        1 gagttggtgg ttcaatacat ccttaatgtt cgtaggttat gcataaaaaa ggccgcttgc
       61 gcggccttag tgattacacg ttgtatcaat gatgatcgac agtatggttg tgctcgatat
      121 cttcattctt gcggctaaag cggcggcgaa ccaccacaaa gaataccgga acgaagaaga
      181 ttgccagtac cgttgcggtc accatcccgc ccattacacc ggtacctact gcgttctgcg
      241 cgccggaacc agcaccagta ctgataacca gcggcataac gccgaggata aacgccaacg
      301 aggtcatcag gattgggcgt aaacgcatcc gcaccgcatc aagcgtcgct tcaatcagac
      361 ctttaccttc tttatccatc aagtctttgg cgaattcgac gataagtatc gcgttcttcg
      421 ccgacaaacc aatggttgtg agcaggccta cctggaagta aacgtcattg gtcaggccac
      481 ggaaggtggc agccagcaac gcaccgataa cccccagcgg aacgaccagc ataacggaga
      541 acggaatcga ccagctctcg tacagcgcag ccagacacag gaacacgaca atcaacgaaa
      601 tcgcgtacag tgaaggtgcc tggttgccgg agagacgttc ctgataggac atccccgtcc
      661 agtcatagcc aacaccggta ggcagtttgc tcgccagttg ttccatcagc tccattgctt
      721 caccggtact tttacccggt gccgcctggc ctaagatttc catagatggc aggccgttgt
      781 aacgttccag acgcggcgaa ccgtactccc aacgagaaga ggagaacgcc gagaacggca
      841 ccatctgacc atcagcagca cgaacatacc agtcgccgat atcatccggc agcatacggt
      901 atttcgcctc tgacatgacg taaactttct tcacacgacc gcggtcgata aagtcgttca
      961 catagctacc gccccatgca gcgcccagag tggtgttaat gtcgttgata gaaacaccca
     1021 gcgcctgcgc tttttcctgg tcgatatcaa tcttaaactg cggggtatct tccagaccgt
     1081 ttggacgtac gctggtcaac atatcagggt gcttcgctgc ttctgcaagc aactggttac
     1141 gcgcctgagt cagtttttcg tgaccaaggc cagcctggtc aatcagctca aagtcaaagc
     1201 cggttgcggt acccagttcc acgattgcgg gcaggttaaa ggcgaaaacc atcgcatctt
     1261 tgatttgcga gaaagcacgt gttgcacgca tggtaatcgc ttcaactttg ttttcttcgc
     1321 ccggacgatc ggcccagtcc ttcaaggaaa cgaacgcaat accggtattc tgaccacgtc
     1381 ccgcaaagcc gaagccgtta acggcgaaca ccgactcaac gttgttcttt tctttggtca
     1441 gatagtaatt cgttacctca ttgagcactt tctgcgtacg ttcctgcgtt gcacctgctg
     1501 gcagctgaac catggtcata aatacgccct ggtcctcatc tggcaagaag gagcttggca
     1561 gacgcacgaa cagataggcc atgccgacca cgatgatcag atacagcacc aggtaacgcc
     1621 ccgtactgcg tagaataccg cctacgctgt cggtgtagtg gtgcgtgctc ttctcgaaca
     1681 tgcggttaaa ccagccgaag aagccttttt taccttcccc gtgatcgcct ttggcaatcg
     1741 gtttcagcat ggtggcacaa agagccggag tcaggatcaa cgccaccagt accgacagcg
     1801 ccattgctga aacaatggta atagagaact gacgatagat agcaccagta gaaccgccaa
     1861 agaaggccat cggtacgaat accgccgaca gtaccatcgc gataccgacc agagcgccct
     1921 gaatctgccc catcgactta cgggtggctt cttttggtgg caaaccttct tccgccatca
     1981 cacgctcaac gttttctacc acaacgatgg cgtcatccac caacaggccg atggcgagca
     2041 ccatcccgaa cattgttagc gtgtttatcg agaagccaaa ggcggcaagg acggcaaagg
     2101 tcccgagcaa taccaccggt acggcaatgg tcggaatcaa cgtcgcgcgg aagttctgca
     2161 agaacagata cattaccagg aacacgagga tgatcgcttc gaccagcgtt ttaaccactt
     2221 cgtgaataga gattttcacg aacggtgtgg tgtcatacgg gtaaacaatt ttcagacccg
     2281 acgggaagaa cggttccatc ttcgccagtt cagcacggat tgccgcagcg gtatccagcg
     2341 cgttcgcacc ggtcgccagc ttgatcccca gaccggaagc cggttggccg ttaaactctg
     2401 cgatgatgtc gtagttctca ccacccagct caattttcgc cacatcacgc agcagcacgc
     2461 gggaaccatc ctgattcact ttcagcagga ttttgccgaa ctcttcagta gaggtcagac
     2521 gcgtctgagc aataatagag gcgttaagct gttggccttt caccggcggc gtaccaccga
     2581 gctgaccagc tgcaacctgg gcgttctgtg ctttgatggc ggtaatgaca tcaaccggcg
     2641 ttagctggaa tttgttcagt tcattcgggt tcatccagat acgcatcgcg tactgtgaac
     2701 cgaacaactg aacgtcaccc acgcccgacg tacggctgat ggcatctttc atattcgccg
     2761 ccacgtagtc ggagatatcc tcctgcgtca tggtgccatc ggtgttgata acgccgacaa
     2821 ccatcaggaa gctgctggat gatttctcaa cgctcacccc ttgctgctgt acttcttgcg
     2881 gcagcaacgg catcgccagc tgcagtttgt tctgcacctg aacctgcgcg atatccgcat
     2941 cagtaccaga ctcaaaggtc agggtgatct gcacggtacc cgtggagtca ctgttagagg
     3001 acatgtacat caggttatcg ataccgttca tattctgttc gataacctgt gtcaccgtgt
     3061 cctgcactgt tttcgcatca gcgccagggt aggaggcgga gatcgttact gccggcggtg
     3121 caatcgtagg atattgcgcc accggcagtt tgaggatcgc cagcccccct gccaacatga
     3181 tgataatggc gatcacccac gcaaaaattg ggcgatcgat aaagaaatta ggcatgtctt
     3241 aacggctcct gtttaagtta agacttggac tgttcaggct gagcaccgct tgcggcttgc
     3301 tggttattat cagcggtaac ttcttgtgct tttacctgga caccaggacg cactttctgc
     3361 agcccactta ttactacgcg atcgcctgct ttcagacctt ctgtcaccag ccacttatcg
     3421 ccgatagcct ggcttgcaac gatcggacgg gtttccactt tgtcatccgc gccaaccacc
     3481 agtacggtgg catcgccacg tggcgtacgg gttacgccct gttgcgggac taaaatagcg
     3541 tttggattaa gcccttcttc cagacgtgca cgcacgaaca tacccggcag cagagtgtga
     3601 tccgggttcg ggaagatagc gcgtagggtg atagacccag tggtctgatc aacggtaacg
     3661 tcagagaatt ccagcgtacc gtcctgcggg aacttaatgc cgtcactggt gatcagcgac
     3721 actttggctt tgccgttctc ttgtttcagc gtgccattcg ccagttcctg tttcaggcgc
     3781 aggaagtcgt tgctggactg ggtcacatca acgtagatcg gatcaagttg ctgcacggtt
     3841 gccagcgcag tcgcctgacc gttctgtacc aatgcgcctt ccgtcacgtt tgacttacca
     3901 atgcgaccac taatcggaga ggtgactttg gtgtaagcca gattgattcg cgcagtttca
     3961 acggcagctt tcgccgcagt taccgcagca ttcgcctgtt gcgcatcagc cagagcctga
     4021 tcgtactctt gtttactgat gtactgagta ccgagcaatt tctgataacg attcaccgtc
     4081 aattgcgcga tattggctgc agcctgggct ttcgccagat cacctttcgc actgtcgtat
     4141 gccgcctgat aggtcgcagg atcaatctga tagagagaga cacctgcttc gatgtcgcta
     4201 ccttctttga aattacgctt caggataatc ccgctaactt gaggacgaac ttctgcgatc
     4261 cggtaggcac tggtgcgacc cggaagctcg gttgtgatct gcagaggttc agttttgact
     4321 gttactacgc caacggcggg catctgctgg ccaccttgtt gggcctgttt gtcgtcacat
     4381 cctgttaggg ctaagctgcc tgagagcatc agaacgaccg ccagaggcgt aaaccctctg
     4441 tttttgttca tatgtaaacc tcgagtgtcc gatttcaaat tggtcaatgg tcaaaagtta
     4501 ataaacccat tgctgcgttt atattatcgt cgtgctatgg tacatacatt cacaaatgta
     4561 tgtaaatcta acgcctgtaa attcacgaac atatggcacg aaaaaccaaa caagaagcgc
     4621 aagaaacgcg ccaacacatc ctcgatgtgg ctctacgtct tttctcacag caggggggat
     4681 catccacctc gctgggtgag attgcaaaag cagctggcgt tacgcgcggt gcaatctact
     4741 ggcattttaa agacaagtcg gatttgttca gtgagatctg ggaactgtca gaatccaata
     4801 ttggtgaact cgagcttgag tatcaggcaa aattccctgg cgatccactc tcagtattaa
     4861 gagagatatt aattcatgtt cttgagtcca cggtgacaga agaacggcgt cgattattga
     4921 tggagattat attccacaaa tgcgaatttg tcggagaaat ggctgttgtg caacaggcac
     4981 aacgtaatct ctgtctggaa agttatgacc gtatagaaca aacgttaaaa cattgtattg
     5041 aagcgaaaat gttgcctgcg gatttaatga cgcgtcgcgc agcaattatt atgcgcggct
     5101 atatttccgg cctgatggaa aactggctct ttgccccgca atcttttgat cttaaaaaag
     5161 aagcccgcga ttacgtcgcc atcttactgg agatgtatct cctgtgcccc acgcttcgta
     5221 accctgccac taacgaataa ccctgaatct gactccagga attttcctgg acattttcgt
     5281 cgttgctatt ctggttcact gcgtcgtgat attcttgcgg tttgactttt tcaggtcgtt
     5341 cttcaggttc agaaaccttc attcatcatg actatgttcc agtattacaa acgatcacgg
     5401 cattttgttt tttcagcatt tattgctttt gtttttgtct tgttatgcca gaacacggcg
     5461 tttgcacggg cgtcatcgaa tggtgattta ccgacaaaag cggacctgca ggcacaactt
     5521 gactcactga ataaacaaaa agatctttct gctcaggaca aactggtgca gcaggatctg
     5581 acagatacat tagccaccct cgataaaatc gatcgcgtaa aagaagagac agttcagcta
     5641 cggcaaaaag tcgctgaagc gccggaaaaa atgcgccagg cgaccgcggc gttaacagca
     5701 cttagtgatg tcgataacga cgaagaaacg cgcaaaattc tgagcgcgct ttcgttgcgc
     5761 cagctggaaa ctcgcgttgc ccaggcgctg gacgatttgc aaaacgcaca aaatgatctg
     5821 gcgtcttata acagccaact ggtttcgtta cagacgcagc ccgaacgcgt gcaaaatgcg
     5881 atgtataacg cttcgcagca gctgcaacaa attcgcagtc gtctggatgg gactgatgtc
     5941 ggcgagactg ccttacgtcc cagccagaaa gtgttaatgc aggtccagca ggctttgctg
     6001 aatgccgaga ttgaccagca gcgtaaaagc ctggaaggga acactgtctt gcaggatacc
     6061 ttgcaaaagc agcgtgatta cgtgacggcg aacagcgccc gtctggagca ccagttacaa
     6121 ctgttgcaag aagcggtaaa cagcaagcgc ctgactttaa ccgaaaaaac ggcgcaggaa
     6181 gctgtctccc cggatgaagc cgcgcgtatt caggctaatc cgctggtgaa gcaggaactg
     6241 gaaattaacc agcagttaag tcagcgtctg attaccgcga ctcaaaacgg taatcagttg
     6301 atgcagcaaa acattaaagt caaaaactgg ctggagcgtg cgctgcaatc ggaacgtaat
     6361 attaaggagc agattgccgt tctgaagggc agtctgctgt tgtcacgtat cctgtaccag
     6421 caacaacaaa cactcccctc ggcagatgaa ctggaaaaca tgaccaaccg catcgcggat
     6481 ttgcgtctcg aacagtttga agtcaaccag cagcgtgacg cgctgttcca gagcgatgcg
     6541 ttcgtcagca aactggaaga aggtcacacc aacgaagtca acagcgaagt tcacgatgca
     6601 ttattgcaag tagttgatat gcgtcgcgaa ttgctggatc agcttaacaa acagttgggt
     6661 aatcagctga tgatggccat taacctgcaa attaaccagc agcagttaat gagcgtatcg
     6721 aaaaatctga aatccatcct gacgcagcaa attttttggg tgaacagtaa ccgcccgatg
     6781 gactgggact ggattaaagc gttcccgcaa acgctgaaag atgaatttaa gtcgatgaaa
     6841 atcacggtga actgggaaaa agcctggccc gccgtattca tcgccttcct cgctggtttg
     6901 ccgctgctgt tgattgccgg gctgatccac tggcgtctgg gctggctgaa agcgtatcaa
     6961 caaaaactgg cttccgctgt gggttccctg cgtaacgaca gccagctcaa cacaccaaaa
     7021 gcgatcctta tcgacctgat ccgcgcactg ccggtgtgcc tgattattct cgctgtcggc
     7081 ctgattctgc tgactatgca gctcaatatc agcgagttat tgtggtcgtt cagcaaaaaa
     7141 ctggcgattt tctggctggt gtttggcctg tgctggaaag tgctggagaa aaatggtgtt
     7201 gccgtgcgtc actttggtat gccggaacag cagaccagcc actggcgtcg gcaaattgtc
     7261 cgcatcagcc tcgcgttgct gccgatccat ttctggtctg tggtggcaga actctccccg
     7321 ctgcatctga tggatgatgt gctggggcag gcgatgattt tcttcaacct gctgctgatt
     7381 gccttcctgg tgtggccgat gtgccgcgaa agctggcgtg ataaagagtc gcacaccatg
     7441 cgactggtca ccattaccgt gctgtcgatt atcccgattg cgttgatggt gctgaccgcc
     7501 acgggttact tctacaccac gctgcgcctc tccgggcgtt ggattgaaac cgtttatttg
     7561 gtgatcatct ggaacctgct gtaccagacg gtattgcgcg gcttaagcgt agcggcgcgg
     7621 cgtatcgcct ggcgccgtgc actggcgcgt cggcagaatc tggtgaaaga gggcgcagaa
     7681 ggtgccgaac cgccggaaga acccaccatt gcgctggagc aggttaacca gcagacgctg
     7741 cgtattacca tgttgctgat gtttgcgctg ttcggtgtca tgttctgggc aatttggtct
     7801 gatttgatca ccgtgttcag ctatctcgac agcattacgc tctggcatta caacgctact
     7861 gaagctggtg ctgcggtggt gaaaaacgtc accatgggca gtctgttgtt tgcgattatc
     7921 gcctcaatgg tggcctgggc gttgattcgc aacctgcctg gtttgctgga agtgctggtg
     7981 ctctcgcgac tgaatatgcg ccagggcgcg tcgtatgcca ttactaccat ccttaactac
     8041 atcattattg ccgttggtgc gatgacggtg ttcggatcgc tgggcgtctc gtgggataaa
     8101 ctccagtggc tggcggcagc attatccgta ggtcttggtt ttggtttaca agagatcttc
     8161 ggtaacttcg tttccggttt gatcattctg ttcgaacgtc cggtgcgcat tggcgacacg
     8221 gtaaccattg gtagcttctc gggtacggtc agcaagatcc gtattcgtgc gacaacgatt
     8281 accgatttcg atcgcaaaga agtgattatc ccgaacaaag cgtttgttac cgagcgtctg
     8341 atcaactggt cgttgactga cacgactacg cgtctggtga tccgtctcgg cgtagcctat
     8401 ggctccgatc tggaaaaagt gcgtaaagtg ttgctgaagg cggcgactga gcacccaagg
     8461 gtgatgcacg aaccaatgcc ggaagtcttc tttacggcat ttggtgccag cacgttggat
     8521 catgagctgc gtctgtatgt gcgtgaactg cgtgaccgta gccgtactgt cgatgagctg
     8581 aaccgtacta ttgatcagtt gtgccgtgaa aacgacatca acattgcctt taaccagctt
     8641 gaagtgcatc tgcacaacga gaagggcgat gaagtgacgg aagtgaaacg cgactacaaa
     8701 ggcgacgatc cgacgccagc ggtagggtaa ggacaataaa gggcgacagt gatgccgccc
     8761 tttatttttt actcgctttg tgaagtctca tcgctctgta acttcttttc ataatcgcgt
     8821 tttacaatat ccagcgcgcg cagcacggtg cgggctggga tctgattttc ttccagcagc
     8881 acaatcaaat cgacggccag tttgacatcg tcaggggcat tttccagtga catactctct
     8941 ccattgctag cgggttaaac gcgctaacct gttttcgatt ttttccagcg catggcggca
     9001 acgtgccagg cgcgcttcat aggcttccac ttcacgatgc agcgtctgct gttccacgag
     9061 atcggtcgct cgcgccagac gggctctacg ttcggcaacc atctcacgta gccgccgctc
     9121 aaaatcctga tgctgaatac gtttacgctg ccagcgggca attttcggtg gtgcgctatc
     9181 ccactcgcgt agcgaccagg ctgtggcttc acgcgctata gcctccagtt gcgccgccag
     9241 atgttctgcc agccaggcga cttgcggcag ctgttgctgc tcaaccgcat gacgaagcgc
     9301 agccaggtta tcgcccgact catcgagaca agcctgtagt gttgtcgcac gggtctgaaa
     9361 aaggtgcctg tcaaaacggg cacttagcgt ggcaaattgc gctaccgggg cacaacgctg
     9421 acgcagcgtg gcgagctgtc cttccagttt ttccagtagc agggcggttt tcacgataag
     9481 acctcaatga aaatgataat tgttatgcta aagtagccac tctgtaagct gacaacactc
     9541 aatatgcaac gaatcatttt aatcatcatt ggctggctgg cggtagtgct gggtacgctg
     9601 ggcgtggtat taccggtatt accgacgacg ccgtttatcc tgctggcggc ctggtgcttt
     9661 gcccgttctt ccccgcgctt tcacgcctgg ttgctgtacc gctcatggtt tggcagctat
     9721 ctacgtttct ggcagaaaca tcatgcgatg ccgcgcggcg caaaaccacg ggcgattttg
     9781 cttattttga ttacgtttac gatttcgctg tggttcgtcc agatgccgtg ggtgcgcatc
     9841 atgttgctgg taattctcgc ctgtttgctt ttttatatgt ggcgaattcc ggtgattgat
     9901 gaaaagcaag aaaagcactg aagcacaaca atcgcagttg caattattgc gtacagccag
     9961 tacattctgg cgttttcgag cacaggcgca ggcggtcaaa ggttaaacaa ctgttacttt
    10021 tgatacgttc aaaacgcgcc gtgagtacca ccgtaacaag caggcataca cttatgaccg
    10081 cgactgcaca gcagcttgag tatctcaaaa atagcatcaa aagcattcag gactacccaa
    10141 aacccggcat tcttttccgc gatgtcacca gcttactgga agacccgaaa gcttacgctc
    10201 tcagcatcga cttgctggtt gagcgttaca aaaatgcggg cattaccaaa gtggtcggca
    10261 ccgaagcgcg tggcttcttg tttggcgctc cggtagctct gggtctgggc gttggctttg
    10321 taccggtccg taaaccgggc aaactgccgc gtgaaaccat cagtgaaact tacgacctgg
    10381 aatacggcac cgatcaactg gaaatccacg ttgatgccat caaaccgggc gacaaagttc
    10441 tggtggtgga cgatctgctg gcaaccggcg gcactatcga agcgaccgtt aaactgatcc
    10501 gtcgtctggg tggtgaagta gctgacgctg cgttcattat caacctgttc gatctcggcg
    10561 gtgaacagcg tctcgaaaaa cagggcatta ccagctacag ccttgtcccg ttcccgggcc
    10621 attaattatc gtcagtcttg cgctgctcac gctacgggca gcacaagatg tgcattcagc
    10681 ctcgccgttc tgacggggct gtgttagcat taccccttcg tgaatccacc ttccagcgtt
    10741 tcagagcctg ccaatgagtt atcaggtctt agcccgaaaa tggcgcccac aaacctttgc
    10801 tgacgtcgtc ggccaggaac atgtgctgac cgcactggcg aacggcttgt cgttagggcg
    10861 tattcatcat gcttatcttt tttccggcac ccgtggcgtc ggaaaaacct ctatcgcccg
    10921 actgctggcg aaggggctaa actgcgaaac cggcattacc gcgacgccgt gcggcgtgtg
    10981 cgataactgt cgtgaaatcg agcaggggcg ctttgtcgat ctgattgaaa tcgacgccgc
    11041 ctcgcgtacc aaagttgaag atacccgcga cctgctggat aacgtccagt acgctccggc
    11101 gcgtggtcgt ttcaaagttt atctcatcga cgaagtgcat atgctgtcgc gtcacagctt
    11161 taacgcactg ttaaaaaccc ttgaagagcc gccagagcac gttaagtttt tgctggcgac
    11221 gaccgatccg cagaaattgc cggtgacgat tttgtcacgc tgtctgcaat ttcatctcaa
    11281 ggcgctggat gtcgagcaaa ttcgccatca gcttgagcac atcctcaacg aagaacatat
    11341 cgctcacgag ccgcgggcgc tgcaattgtt ggcacgcgcc gctgaaggca gcctgcgaga
    11401 tgccttaagt ctgaccgacc aggcgattgc cagcggtgac ggccaggttt caacccaggg
    11461 ggtcagtgcg atgctgggta cgcttgacga cgatcaggcg ttatcgctgg ttgaagcgat
    11521 ggtcgaggcc aacggcgagc gcgtaatggc gctaattaat gaagctgctg cccgtggtat
    11581 cgagtgggaa gcgttgctgg tggaaatgct cggtctgttg catcgtattg cgatggtaca
    11641 actttcgcct gctgcacttg gcaacgacat ggccgccatc gagctgcgga tgcgtgaact
    11701 ggcgcgcacc ataccgccga cggatattca gctttactat cagacgctgt tgattggtcg
    11761 caaagaatta ccgtatgcgc cggaccgccg tatgggcgtt gagatgacgc tgctgcgcgc
    11821 actggcgttc catccgcgta tgcctctgcc tgatccagaa gtgccacgcc agtcctttgc
    11881 gcccgtcgcg ccaacggcag taatgacgcc aacacaggtg ccgccgcaac cgcaatcagc
    11941 gccgcagcag gcaccgactg taccgctccc ggaaaccacc agccaggtgc tggcggcgcg
    12001 ccagcagttg cagcgcgtgc agggagcaac caaagcaaaa aagagtgaac cggcagccgc
    12061 tacccgcgcg cggccggtga ataacgctgc gctggaaaga ctggcttcgg tcaccgatcg
    12121 cgttcaggcg cgcccggtgc catcggcgct ggaaaaagcg ccagccaaaa aagaagcgta
    12181 tcgctggaag gcgaccactc cagtgatgca gcaaaaagaa gtggtcgcca cgccgaaggc
    12241 gctgaaaaaa gcgctggaac atgaaaaaac gccggaactg gcggcgaagc tggcggcaga
    12301 agccattgag cgcgacccgt gggcggctca ggtgagtcaa ctttcgctac caaaactggt
    12361 cgaacaggtg gcgttaaatg cctggaaaga ggagagcgac aacgcagtat gtctgcattt
    12421 gcgctcctct cagcggcatt tgaacaaccg cggcgcacag caaaaactgg ctgaagcgtt
    12481 gagtacgttc aaaggttcaa cggttgaact gactatcgtt gaagatgata atcccgcggt
    12541 gcgtacgccg ctggaatggc gtcaggcgat atacgaagaa aaacttgcgc aggcgcgcga
    12601 gtccattatt gcggataata atattcagac cctgcgtcga ttcttcgatg cggagctgga
    12661 tgaagaaagt atccgcccca tttgatcgta agcacagctt acgttcgtca tccttaacgt
    12721 gattgagaga gaaacctatg tttggtaaag gcggtctggg taacctgatg aagcaagccc
    12781 agcagatgca agaaaaaatg cagaaaatgc aggaagagat cgcgcagctg gaagtcaccg
    12841 gcgaatctgg cgcaggtctg gtaaaagtga ccatcaacgg tgcacacaac tgccgtcgcg
    12901 tagagatcga cccgagcctg ctggaagacg acaaagagat gctggaagac ctggtggctg
    12961 cagcattcaa cgacgcagca cgtcgtattg aagaaacgca gaaagaaaaa atggcctctg
    13021 tatcctccgg aatgcagctg ccgcctggct ttaagatgcc gttctgatgc aaaccagccc
    13081 gctgttaaca cagcttatgg aagcactgcg ctgtctgccg ggcgttggcc cgaagtcggc
    13141 gcagcgtatg gcgttcacgc tgcttcagcg cgatcgtagc ggcgggatgc gtctggcgca
    13201 ggcgctcacc cgggcgatgt cggaaatcgg ccactgcgcc gattgtcgca ccttcaccga
    13261 acaggaagtc tgtaacatct gttcgaatcc acgtcgtcag gaaaacggtc aaatctgcgt
    13321 ggtggagagt ccggcggaca tttacgccat cgagcagacg gggcagtttt caggtcgtta
    13381 ttttgtgttg atgggacacc tgtcaccgct ggacggcatc ggtcctgatg atatcgggct
    13441 tgatcgtctg gaacagcgtc tggcagagga aaaaatcact gaagtgatcc tcgccaccaa
    13501 ccccacggtt gaaggtgaag ctaccgctaa ctacattgcc gagctttgtg cgcaatatga
    13561 cgtggaagcc agccgaatcg ctcatggcgt accggttggc ggcgaactgg aaatggtcga
    13621 tggcaccacg ctgtcacact cccttgccgg gcgtcataag attcgttttt aagcaaacga
    13681 gagcaggatc acctgctctc gcttgaaatt attctccctt gtccccatct ctccctcatc
    13741 ctgtttttaa ccttaaaatg gcattattga ggtagaccta catgaaagga caagaaactc
    13801 gtggttttca gtcagaagtg aaacagcttc tgcacctgat gatccattct ctctattcca
    13861 ataaagaaat cttcctgcgt gagcttatct ctaacgcctc cgatgcggcg gacaagctgc
    13921 gtttccgcgc gctttctaac ccggacctgt acgaaggtga tggtgaacta cgcgttcgtg
    13981 tctctttcga taaagacaag cgcacgctga ccatctccga taacggcgtg gggatgaccc
    14041 gcgacgaagt gattgaccat ctggggacta tcgctaaatc cggcaccaaa tcattcctcg
    14101 aatccctggg ttctgaccag gcgaaagaca gccagctgat cggtcagttt ggtgttggtt
    14161 tctactctgc gtttatcgtg gctgacaaag tgaccgtgcg tactcgcgcg gcaggcgaaa
    14221 aaccagaaaa cggcgtcttc tgggaatcgg ctggcgaagg tgaatacacc gttgccgaca
    14281 tcactaaaga agatcgtggt actgaaatca ccctgcatct gcgtgaaggc gaagacgagt
    14341 tcctcgatga ctggcgtgtg cgttccatca tcagcaaata ttccgaccat atcgcgctgc
    14401 cggtagagat cgaaaaacgc gaagagaaag acggcgaaac cattatctcc tgggagaaaa
    14461 tcaacaaagc gcaggcgctg tggactcgta acaagtcgga aatcaccgat gaagagtaca
    14521 aagagttcta caaacacatc gcccacgact ttaacgatcc gctgacctgg agccacaacc
    14581 gcgttgaagg taagcaggag tacaccagcc tgctgtacat tccgtctcag gcaccgtggg
    14641 atatgtggaa ccgcgatcat aaacacggtc tgaaactgta tgttcagcgt gtgttcatca
    14701 tggacgacgc agaacagttc atgccgaact atctgcgctt cgtgcgtggt ctgattgact
    14761 ccagcgatct gccgctgaac gtttcccgtg aaatcctcca ggacagcacg gtaacgcgta
    14821 acctgcgcaa tgcgctgacc aagcgtgtgc tgcaaatgct ggaaaaactg gcgaaagacg
    14881 acgcggaaaa ataccagacc ttctggcaac agtttggcct ggtactgaaa gaaggtccgg
    14941 cggaagattt cgctaaccag gaagcgatcg ccaaactgct gcgttttgct tctacccata
    15001 ccgattcttc tgcgcagacc gtgtctctgg aagactacgt ttcccgcatg aaagaagggc
    15061 aggagaaaat ctactatatc accgcagaca gctacgcggc agcgaagagc agcccgcacc
    15121 tggaactgct gcgtaagaaa ggcatcgaag ttctgctgct ttccgaccgc atcgatgagt
    15181 ggatgatgaa ctatctgact gagttcgacg gtaaaccgtt ccagtctgtg tctaaagttg
    15241 acgagtcgct ggaaaaactg gctgacgaag ttgatgagag cgcgaaagaa gcggagaaag
    15301 cactgactcc gttcatcgac cgtgtgaaag ccctgctcgg cgagcgcgtg aaagatgtcc
    15361 gtctgactca ccgtctgacc gatacgccag cgatcgtttc gaccgacgcg gacgaaatga
    15421 gcactcagat ggcgaaactg ttcgctgcgg cgggccagaa agtgccagaa gtgaaataca
    15481 tcttcgaact gaacccggat cacgtactgg tgaaacgtgc ggcggatact gaagatgaag
    15541 cgaagttcag cgagtgggta gaactgctgc tggatcaggc gctgctggca gaacgcggca
    15601 cgctggaaga tccgaacctg tttattcgtc gtatgaacca gctgctggtt tcctgatgtc
    15661 atgccggatg accttcgtgt catccggcat ttttcttttc ttcatctgca ctttccgcaa
    15721 attatcttgc cattaaccgt ttcagcctca ggtgcctttc ttgaggcaat cgcctgttgg
    15781 tggtatcgtt tatcgctttt tcaaaaaatt cgacacattt taaggggatt ttcgcaatgc
    15841 gtatcattct gcttggcgct ccgggcgcgg ggaaagggac tcaggctcag ttcatcatgg
    15901 agaaatatgg tattccgcaa atctccactg gcgatatgct gcgtgctgcg gtcaaatctg
    15961 gctccgagct gggtaaacaa gcaaaagaca ttatggatgc tggcaaactg gtcaccgacg
    16021 aactggtgat cgcgctggtt aaagagcgca ttgctcagga agactgccgc aacggtttcc
    16081 tgttggacgg cttcccgcgt accattccgc aggcagacgc aatgaaagaa gcgggcatca
    16141 atgttgatta cgttctggaa ttcgacgtac cggacgaact gattgttgac cgtatcgtag
    16201 gccgccgcgt tcacgcgccg tctggtcgtg tttatcacgt taaattcaat ccgccgaaag
    16261 tagaaggcaa agacgacgtt accggtgaag agctgactac ccgtaaagac gatcaggaag
    16321 agaccgtacg taaacgtctg gttgaatacc atcagatgac tgcaccgctg atcggctact
    16381 actccaaaga agcggaagcg ggtaacacca aatacgcgaa agttgacggc accaagccgg
    16441 tggctgaagt tcgcgctgat ctggaaaaaa tcctcggcta atcaagccgc agcagatctg
    16501 ctttcgggca ggtctgctca tcctcctcag gcaatacctc ttacagcaat tagttcttct
    16561 tcttcacttt tccgctacaa ttatcaacaa gttgaatcga taagaggcgg taatgcgtca
    16621 gactaaaacc ggtatcctgc tggcaaacct gggtacgccc gatgccccca cacctgaagc
    16681 ggtaaaacgc tatctgaaac aatttttaag cgacagacgc gtggttgata cctcacggtt
    16741 gttatggtgg ccgttgctgc gcggcgtgat tttgccgctg cgttcgccgc gtgtggcgaa
    16801 gctgtatgcc tctgtctgga tggaaggtgg ctcgccgctg atggtttaca gccgccagca
    16861 acagcaggcg ctggcgcaac gtttaccgga gacgcccgtg gcgctgggaa tgagctacgg
    16921 ctcgccatca ctggaaagcg ccgtagatga acttctggca gagcatgtag atcatattgt
    16981 ggtgctgccg ctttatccgc aatactcctg ttcaacggtc ggtgcggtat gggatgaact
    17041 ggcacgcatt ctggcgcgca aacgtagcat tccggggata tcgtttattc gtgattacgc
    17101 cgataaccac gattatatta atgcactggc gaacagcgta cgtgcttctt ttgccaaaca
    17161 tggcgaaccg gatctgctgt tgctctctta tcatggcatt ccccagcgtt atgcagatga
    17221 aggcgatgat tacccgcaac gttgccgcac aacaactcgc gaactcgctt ccgcactgga
    17281 gatggcaccg gaaaaagtga tgatgacctt tcagtcgcgc tttggccggg aaccctggct
    17341 gatgccttat accgacgaaa cgctgaaaat gctcggagaa aaaggcgtgg gtcatattca
    17401 ggtgatgtgc ccgggctttg ctgcggattg tctggagacg ctggaagaga ttgccgagca
    17461 aaaccgtgaa gtcttcctcg gcgctggcgg gaaaaaatac gaatatattc cggcgcttaa
    17521 tgctacaccg gagcatatcg aaatgatggc taatcttgtt gccgcgtatc gctaaagctg
    17581 agcggtaaag aactgagcgc cgtcgcgaag agcctcgtcg gcggttttca tcatccgtga
    17641 ataatgcaaa aaggcgtgca gcgtgcctgg gtagagtttg aactcacagg gctgctgatg
    17701 cgccgctaac gtctggtaaa gcagatggct gtcatccagc agcggatcga actccgcccc
    17761 ggcaataaaa cagggcggaa cttcgcgagt gagatcatta ttaaacaggc agtaatatgg
    17821 cgactcgcgg tccgcgtcgt tgcttaaata cgcctcttca tacatctgca aatcctgttg
    17881 cgttaagcca tcccagacac cacccaacag acgacgagcc acggaatccc gtaatccgta
    17941 aagcccatac cacagcaaaa cgcccgcaac tttaccgcaa tcgatctgtt tatcgcgcaa
    18001 ccacaacgca ctggcgagcg ccagcatggc acctgcggaa tcaccggcaa aaccaatgcg
    18061 ggacatattg atttgataat cctccgcctg ctggtggaaa taacaacagg cagccacaat
    18121 ttcctctatc gcttgcggaa aacgcgcttc aggtgaaagg gtgtaatcaa tgccaatcac
    18181 cgtacattgg ctgtagcttg ccagcaggcg catgatgcga tcgtgggtat cgagattgcc
    18241 gagaataaaa ccgcctccat gcaaataaaa tagcgtcgcc gggctatctg gctgcggata
    18301 aaagatacgt gttttcacct gcccatattt tgttggaacc ctgtaagctc tggttgccat
    18361 ttctggagcg tccgcattcc agaatcggcg ctcaagcgtg taatactgtc gttgctcagc
    18421 aatcgctccc gttgcaggcc agggcggtaa atccggctga agagtattca caacggtctt
    18481 catttcagca gagataaggt ccagaacggg taatttgttt tccggcttca tgcaaaaact
    18541 cctttcaaat tacgtcattg taaggaacca ctgccatgaa aatgcgatcc cgcctgctga
    18601 tattgaaact ggctgcgtct cgcgcgctcc cgtcagattg tgttaacatt cgccgctcag
    18661 ttaaccaccc gtaaaaacaa ccatgaaatt tcccggtaaa cgtaaatcca aacattactt
    18721 ccccgtaaac gcacgcgatc cgctgcttca gcaattccag ccagaaaacg aaaccagcgc
    18781 tgcctgggta gtgggtatcg atcaaacgct ggtcgatatt gaagcgaaag tggatgatga
    18841 attcattgag cgttatggat taagcgccgg gcattcactg gtgattgagg atgacgttgc
    18901 cgaagcgctt tatcaggaac taaaacagaa aaacctgatt acccatcagt ttgcgggtgg
    18961 caccattggt aacaccatgc acaactactc ggtgctcgcg gacgaccgtt cggtgctgct
    19021 gggcgtcatg tgcagcaata ttgaaattgg cagctatgcc tatcgttacc tgtgtaacac
    19081 ctccagccgt accgatctta actatctaca aggcgtggat ggcccgattg gtcgttgctt
    19141 tacgctgatt ggcgagtccg gggaacgtac ctttgctatc agcccgggcc acatgaacca
    19201 gctgcgggct gaaagtattc cggaagatgt gattgccgga gcctcggcac tggttctcac
    19261 ttcttatctg gtgcgttgca agccgggtga acccatgccg gaagcaacca tgaaagccat
    19321 tgagtacgcg aagaaatata acgtaccggt ggtgctgacg ctgggcacca agtttgtcat
    19381 tgccgagaat ccgcagtggt ggcagcaatt cctcaaagac cacgtctcta tccttgcgat
    19441 gaacgaagat gaagccgaag cgttgaccgg agaaagcgat ccgttgttgg catctgacaa
    19501 ggcgctggac tgggtagatc tggtgctgtg caccgccggg ccaatcggct tgtatatggc
    19561 gggctttacc gaagacgaag cgaaacgtaa aacccagcat ccgctgctgc cgggggctat
    19621 agcggaattt aatcagtatg agtttagccg cgccatgcgc cacaaggatt gccagaatcc
    19681 gctgcgtgtc tattcgcaca ttgcgccgta catgggcggg ccggaaaaaa tcatgaacac
    19741 taatggagca ggggatggcg cactggcagc gttgctgcat gacattaccg ccaacagcta
    19801 ccaccgtagc aacgtaccaa actccagcaa acataaattc acctggttga cgtattcgtc
    19861 attagcgcag gtgtgtaaat atgctaaccg tgtgagctat caggtactga accagcattc
    19921 acctcgttta acgcgcggct tgccggagcg tgaagacagc ctggaagagt cttactggga
    19981 tcgttaagtt atcgtcggtt cgtaggccag ataaggcgtt cacgccgcat ctggcatttt
    20041 gctctcaatg cctgatgcga cgctggcgcg tcttatcagg cctacatatc cgcgcctatt
    20101 atccggcaac caccgtttac ctcgtcacca cctcacccgc cggtggcgtt tccagcagtt
    20161 ccagcatagt acgggcaatt tcacgctcac ccatcactac ctgattcgca ccacgttcgg
    20221 tgatatacgc cacttcatcg tcataatggg cgcgggcaat aatctcaata tccggatttt
    20281 tcgcgcgggc agatgccaca atctcgcccg cttcatagcc gttgggaatc gtcaggatca
    20341 gccattttgc acattccaga tgcgccagtt gcataatttc ttcgttagcc gcattgccca
    20401 atactgcgcg gaccccgcgc tcgcgcagct catcaacacg ggttcgtgac gtctcaatca
    20461 ccaccagcgg aatatcagag gcgagcaatt tctcccccag caggctgcct acacgaccgt
    20521 aacccaccag tagcgcatgg ttgcaaatat ccactgggat ctgcttctct tcttcgattg
    20581 cctcttccag cgtctgctct tccagcgttt cggtcttcgc cagatatttc tccagtagtg
    20641 cgaacagtac cgggttgagc ataatcgaca ggatcgcccc tgccagtacc aggttttgtc
    20701 cggcctgcgg cagtaaattc aatgccattc ctagtcccgc caggataaac gcgaactcac
    20761 caatctgcgc caggctggcg gcgatggtta acgccgtgcg ctgggagtga ccaaacaaac
    20821 gcacaaggaa cagggccgcg accgatttac caaacagaat aattgccagc gtcgccagta
    20881 ctgccagcgg ttgctgaatc agaattaacg gatcaaacaa catcccgacg gagacaaaaa
    20941 acagcaccgc aaacgcgtcg cgcaatggca gtgtatcgtg ggcggcacgg tgactcagtt
    21001 cagactcgtt cagtaccatc ccggcaaaga acgcaccgag tgcaaaggag acatcaaaca
    21061 gctctaccgc accaaaggca atccctaacg ccagcgccag caccgacagg gtaaacagct
    21121 cgcgggaacc ggttgctgcg ctgcgtgcca taatccacgg caccagacgg cgacctacca
    21181 gcatcataat ggcgataaat gcgatcacct tgccgatggt gatccccata tcgactgcaa
    21241 gagtggcaaa gcccacatcg ccctgttcca tcattcctgc taccgcgggt agcaatacca
    21301 gtgtcaggac catcaccagg tcttccacaa tcaaccaacc gatggcgatt tgcccacgct
    21361 gactgtcaat taattgccgt tcttcaagtg cgcgcagtaa caccacggta ctggcggtgg
    21421 aaagacataa gccgaacacg ataccggtca ttaacgacca gcccagcacg gcggagagcg
    21481 ccatacccag cagcgtcgcc acggctatct gggcgatcgc gccgggaatg gcgatggact
    21541 ttaccgccat caaatccttg agcgaaaaat gcaaaccgac gccgaacatc agcaaaataa
    21601 cgcccagttc agccagttcc ggcgcaagct tagtatcggc aacaaagccc ggagtgaatg
    21661 gtcctgccag cacacccgct aacagatatc ccaccagagg agaaatacgt agtttattgg
    21721 ccagcatgcc gaggataaag gcgagcacaa ggccgccaac aatggtggtg ataagcgggg
    21781 tggcgtgatg cattccgtct ccttttcctg gtggttattg tccatttttg gccgggaaaa
    21841 ccaaaattac aggtaatagt ttatgacaat ttcattgatg atgtttatga ataattgttg
    21901 aattttgcag aaaaatggaa ttagctgcaa aaaaaagcac ggatcggaaa acagaaggcg
    21961 gtttaacaga ggaaaggctt atggcgactg taaaacgatg cagccaaagt ttgcctttgg
    22021 ctgcaatgaa atcagtcttt atgccggtta tcaggcagga atatggtcaa catccccaat
    22081 agtggcagga aagcacagat tttatagact aactctatgc tggtgtggtc ggcgataagc
    22141 cccagaactg ccgcccccag acctcccatg ccgaaagcaa aaccgaaaaa tagtccagaa
    22201 accataccga tacgtcccgg aagcagctcc tgggcataga ccagaatggc agagaatgcc
    22261 gaagcgagga taaatccaat aatcaccgtt aaaacccccg tccagtgcag gctggcgtag
    22321 ggtaaaatca gcgtaaacgg cgcaacgccg aggatagagc cccaaatcac atatttccgt
    22381 ccaattttat cccctacagg cccgccaatc accgtacctg ccgcaacggc aaacaggaag
    22441 gcaaacaaat gaagctgagc attctggata gataatccga atttttgcat cagataaaag
    22501 gtgtaatagc tgctgatgct cgccatatag aaatatttcg agaaaatgag gattaacaga
    22561 atgctgaccg ccagaacaac tttattgcgc ggcagtggat tgataatcgt cgctttgggt
    22621 tttcctttat tcattcggtg ctgtgccgag taccaacggc tgatttgcgc caacaccacg
    22681 atcgccagca gtgccgcaag cacaaaccag gcaacgttgc ctttgccata aggcgcgata
    22741 atcaccgccg ccagcaaggg gcccagggaa ctgccaaagt tgccgccgac ctgaaatata
    22801 gattgcgcca ggccatgacg cccgccggaa gccatacggg ccacgcgaga agattccgga
    22861 tgaaagaccg atgaaccggt accgaccagc gccgctgcca gcagaactgc gccgaaactg
    22921 cccgccagcg ccagcagcac cagaccactt aaggtaaagc acatgccaat cggcaacgac
    22981 cacggcatcg gatatttatc ggtccagtag ccgaccaccg gttgcagtag cgaagaggcg
    23041 agctggaagg tgagggttat catgccaatc tgcataaatg tcagagaaaa ttctgactga
    23101 agcagtggat aaatcgccag aatcagcgat tggatcatgt cgttcagcag atgtgagagg
    23161 ctgatagcac ctaaaatacc aaacgatgtt cgggccttag tcgttgacgc agccgcgccc
    23221 gccacaggct gggtttgttc actcattgcc ataggaaagt cactttttca gggttgcgat
    23281 gtaaagaatg atcttatttg tgattattac ccgactaaca tacctgtatg cgccgcctga
    23341 aggaagtctc aacacggaat acagaatttc taatctggat gcagatttat cttcaccgga
    23401 cgcagacttg tttatgatgt cgcgtcatac tatttttcaa cacgttgaaa tcaggtcagg
    23461 gagagaagta tgaaattatt gcagcggggc gtggcgttag cactgttaac cacatttaca
    23521 ctggcgagtg aaactgctct ggcgtacgag caggataaaa cctacaaaat tacagttctg
    23581 cacaccaatg atcatcatgg gcatttttgg cgcaatgaat atggtgaata tggtctggcg
    23641 gcgcaaaaaa cgctggtgga tggtatccgc aaagaggttg cggctgaagg cggtagcgtg
    23701 ctgctacttt ccggtggcga cattaacact ggcgtgcccg agtccgactt acaggatgcc
    23761 gaacctgatt ttcgcggtat gaatctggtg ggctatgacg cgatggcgat cggtaatcat
    23821 gaatttgata acccgctcac cgtattacgc cagcaggaaa agtgggctaa gttcccgttg
    23881 ctttccgcca atatctacca gaaaagtacc ggcgagcgcc tgtttaaacc atgggcgctg
    23941 tttaagcgtc aggatctgaa aattgccgtt attggcctga cgacggatga cacagccaaa
    24001 attggtaatc cggaatattt cactgatatc gaatttcgta agcccgctga tgaagcgaag
    24061 ctggtgattc aggagctgca acagacagaa aagccagaca ttattatcgc ggcgacccat
    24121 atggggcatt acgacaatgg tgagcacggc tctaacgcac cgggcgatgt ggagatggca
    24181 cgcgcgctgc ctgccggatc gctggcgatg atcgtcggtg gtcactcgca agatccggtc
    24241 tgtatggcgg cagaaaacaa aaaacaggtc gattacgtgc cgggtacgcc atgcaaaccg
    24301 gatcaacaaa acggcatctg gattgtgcag gcgcatgagt ggggcaaata cgtgggacgg
    24361 gctgattttg agtttcgtaa tggcgaaatg aaaatggtta actaccagct gattccggtg
    24421 aacctgaaga agaaagtgac ctgggaagac gggaaaagcg agcgcgtgct gtacacccct
    24481 gaaatcgctg aaaaccagca aatgatctcg ctgttatcac cgttccagaa caaaggcaaa
    24541 gcgcagctgg aagtgaaaat aggcgaaacc aatggtcgtc tggaaggcga tcgtgacaaa
    24601 gtgcgttttg tacagaccaa tatggggcgg ttgattctgg cagcacaaat ggatcgcact
    24661 ggtgccgact ttgcggtgat gagcggaggc ggaattcgtg attctatcga agcaggtgat
    24721 atcagctata aaaacgtgct gaaagtgcag ccattcggca atgtggtggt gtatgccgac
    24781 atgaccggta aagaggtgat tgattacctg acagccgtcg cacaaatgaa gccagattca
    24841 ggtgcctacc cgcaatttgc caacgttagc tttgtggcga aagacggcaa actgaacgac
    24901 ctgaaaatca aaggcgaacc ggtcgatccg gcgaaaactt accgtatggc gacattaaac
    24961 ttcaatgcca ccggcggtga tggctatccg cgccttgata acaaaccggg ctatgtgaat
    25021 accggcttta ttgatgccga agtgctgaaa gcgtatatcc agaaaagctc gccgctggat
    25081 gtgagtgttt atgaaccgaa aggtgaggtg agctggcagt aatgaacccc gtcgcggcgt
    25141 catgatatga cgccgccatt tatgaatatt gaaatcttgc atcgtaatcg cgatgtgtca
    25201 aaccaaatgc catcagcata taattctgcg gatcaccagg ctgttcttca tctgcttcaa
    25261 accaaagtgt cacgcctgag cgattgacgt ggattaagag tgtatggggc gattgacggc
    25321 ggatttgcag atcagcgcct tcgttaacaa gcatgttaaa tacacgcgta acgttcaact
    25381 cagcgacgtt attcaatatt cctttatcaa atcggatcgc tttgcccaaa tggatttggc
    25441 tcagataatc gcaccaaatc atatatagct tgttgttttc gaaatgaaac tcaacattac
    25501 caaatagcca gatataaaaa ccatttccca tatcattttt agagtccggc tcaacaaagt
    25561 tttgttccaa ccatgccatt gtttgcccca gttcgacaaa atcgaatttt ccgttaaaga
    25621 caaaattgtg gaagctaaca tcaacaagat ggtcaaattt catctttcgc tcctttgtga
    25681 attttttaca tgcttcaaaa gccagcgtaa tttacatcgg tgcaggcgac tctccagtgt
    25741 tgagcgaaaa tttgcgatgt cgacattgga ccgatctacc gcagcaaccc ccgtgtattg
    25801 tgggatcggt gaagggattt tttgtaactt tcccagcgcc agcagttgtt gaatgatcct
    25861 gctaccgtcg tggtaatcat cgtaaatagc cactggcaga ggctgccagg cgggggtcga
    25921 tttgataaat ccggaaaaaa aatacgggtc cagatcgccg aaatcaaagc cgtaggcgag
    25981 gggaacttca atattttgct ctgttttttt attctcaaat gtacaatgaa aaccgtgaaa
    26041 acaatactgc cactttccca ttttgccttt tcgcttacgg ttgcatttga agggggcaaa
    26101 ggtaactagc gggttatttt ccgccatctc aacgttcagt tgttcagcca atgcaaatat
    26161 aagctctgtc gccagcttac gatattcttt cgcgcagtgt tcgaaaaaat cctgatggcg
    26221 gttaatctct tcaagcgata ttaatctggc gatcctgata accgggtcgg cagaatgcat
    26281 gccaacaaca aattcatcga gctgtgcttt cagcaccagc ccgaattcct cacgatacct
    26341 ctctgcttcg ctggcaaaat gcagatgtaa taccttctct ctcgatgttt gccgaagtaa
    26401 ggcgatatcc ggtatctcat ctgcacaagc gatacttaat gtctctgtaa tcctttccac
    26461 atctcatctt ccgtgtgcat cacttaatcg cgacgggcga tatcagcaaa tttggcatcg
    26521 agtatctttg ccaggtcgct tgccgccagt tcgatatcca gtccgcgctt gccgccggaa
    26581 acataaatag tggcaaattc ttgtgcgggg gcgtcgataa tcgttggcag acgttttttc
    26641 tgccccagtg ggctaatccc ccctaccaga taccccgtcg aacgctgcgc gaccatcgga
    26701 tcggccatct caactttctt ggcacccagc gcttttgcta cttttttaag atccagttga
    26761 cctgcgaccg gcgtaacagc cacggcaagg tgtttcatat caccgttcac tgcgaccagc
    26821 agcgttttgt agacctgatc cggattcaaa cctaattttt tgacgacttc atcgccaaaa
    26881 ttggtttcag caggatcgtg ctcgtaggtg tggatttgaa acgaaatctt gtttttttcg
    26941 agtaatttaa ctgcgggtgt catggtaatt ttcctgcctt aaacaaaaaa acgaagcaag
    27001 catacgcctg atggcggtcc aaaaaaaaga gtcatcttgc ctaagagtat tggcaggatg
    27061 gtgagattga gcgacaatcg agttacaccg tcgcttaaag tgacggcata ataataaaaa
    27121 aatgaaattc ctctttgacg ggccaatagc gatattggcc atttttttag cgcaacatct
    27181 gcggcaaatt cccttctcca tacaggtgta gtgcaccgac cgcgaccaca tagcgccccg
    27241 gcggcatggc gcgtaatttg tcccgccagg cgaggtttcg ctgatgcatc agcacatcgt
    27301 acagcgactg actgaacgta ttgggcagcg ttatatcatt attttgcggc ggtgcattca
    27361 gccaccagct catcatttgt tgcagcaacc gtgcgttggt gtgccagtgg gtcagcgtat
    27421 cgtccagcag cgccagtcct ttgtcaggga gctggagcaa catggcaatc tggttttcag
    27481 ccccttccag ttcaatcacg ggtttatgtt gttgcttagc cgcctgcaat agctggtaat
    27541 cgataccgta ttctgcccgc agccccagtt tttgcgcctg cgtcgcctga agaaccatcg
    27601 cgatttgcca cagcggttgg gtagaaaaga gcgacggaga aatgcccatc tcctggctaa
    27661 tgtgctgcag gttttggagt tggtcctcgc taatgcgctc ttccagggcc tcgcaggcag
    27721 gcaaattggc aaaaggcgta tcgctggtgg aaacatccgc ctcgacgatc agcgcatcgg
    27781 cgtttttgag ctttttgagc aaacgggtgg gcaggggagc catatcgtgg ctacccatat
    27841 gaatactgcc gatcagatga aaatggcgat tgccgggaag agagatatcg atagcaggcc
    27901 aggtgtaatg attaccgcgc agcgcggccc aaagcgtttt tacccggtac aacagatcca
    27961 tacgacctcc ctttgtgaaa tatcatgcta gcgcgcgggg agggatggcg caaatggagt
    28021 tgattgttgc acttgtgcac agtgcttgtg tgcattacaa tgattaaata atggacaagg
    28081 agatgagaga ggaatggctc aaaagaaaaa tataaggagt tttcgtgatg cctggttggc
    28141 tgattttttt gtccattcaa cgccacatcg aaagatccct gctgaaatcc ataccacgtt
    28201 atcacgaaag ttggacatca ttaatgctgc cacttctcat cgggatttac gctcccctcc
    28261 ggggaaccga tacgaagagt tatccgggaa attacaggaa tactcctcca ttagagtgaa
    28321 taaacagtac cgactgattt ttaaatgggt taatggcaag gccgaagaat tgtttttaga
    28381 cccacacaac tactaaaaca tagctgtcgt attgacgaga aaggtaaaac tatgaaacag
    28441 gcaacaagaa aaccgacgac acccggagat attcttctct atgaatatct ggaaccgctc
    28501 gatttgaaaa tcaatgagtt agcagagttg ctgcatgttc atcgtaatag cgtcagtgca
    28561 ctgatcaata acaatcgtaa actcaccact gagatggcat tccgtctggc gaaagttttt
    28621 gataccacag tcgatttttg gctaaacctc caggcggcag ttgatctttg ggaagttgaa
    28681 aacaacatgc gtacccagga agaattggga cggattgaaa cagtggctga atatttggca
    28741 cgccgtgaag agcgtgcaaa aaaggtcgcg tagaataatt tccctataac ggatgcgcca
    28801 ccctaaagca gcgcatccgc aatgatgtac ttattccttc ggtttaaacc gcagcaatcg
    28861 gttggcgtta ctcactacgg tgatcgacga gagcgccatt gccgctccgg caaccaccgg
    28921 gttaagcagt gttccagtga acggccacaa aataccggcg gcgaccggaa taccaatgct
    28981 gttgtagata aacgcaccga gcagattctg cttcatgttg cgcagcgttg cgcgggaaat
    29041 tgcaagcgca tccgcaacac ccatcaggct atggcgcatc agggtaatcg ccgcggtttc
    29101 aatggcaaca tcactgccgc cacccatcgc aataccgaca tccgcctgag ccagcgctgg
    29161 cgcgtcgtta atgccgtcgc ctaccattgc cacctgacgt ccttcacttt gcagacgttt
    29221 gatcgcttcg gctttaccgt ctggcagcac gccggctatc acctcatcaa tccctgcttc
    29281 tttggcgatc gcattggcgg tggtcgggtt atccccggtt agcatcacca ggcgatatcc
    29341 cgctttatgc aggcgttgca gcgccgccac gctatcacta cgcaacggat cgcgtacagc
    29401 cagcagggct accgctttcc cgtcaaccgc cagcagcaca ggcgttgccc cttgcgatgc
    29461 ctgagctgaa atatctgctt caattgcttt ggtatcgacc tgttggtcat ttaacagcgc
    29521 ctgattgccc agcaataacg catgaccttc agcttcaccg ctcacgccca gcccgcgcaa
    29581 tgtgcggaaa ccgttgacct gcggtagctg catatcacct gctttatcga ggatcgcccg
    29641 tgccagaggg tggctggaac cttgctccag cgccgccgcc agacgcaatg cttgcgcttc
    29701 atcaatatca gcaaatgttt ttactgcgac aacctgcggc ttcccttcgg tcagcgtccc
    29761 ggttttatcg aacactacgg tgtcgagcgt actggcgcgt tgcagcgcgt cggcgtcccg
    29821 taccagcacg ccaaactcag ccgcccgccc gacgcccgaa ataatcgaca tcggcgtcgc
    29881 cagccccagc gcacacggac aggcaataat cagcaccgtg gtggcaatca ccagggtata
    29941 gacaatctgc ggtgccggac caaagaaata ccagattgcc gcactgatca gcgcaatcac
    30001 caccactacc ggcacaaata cggctgagat tttatccgcc agctgaccga tttctggctt
    30061 actgctctgg gcctggcgca ccatacgaat aatccgcgac agcgtagtat ggctgccaac
    30121 cgcactggcg cgaaacagca cgctaccgtc ctgcaccact gtcccggcat ggacgctatc
    30181 gccttcgcct ttttgctgcg ggataggttc gcccgtcagc atcgcttcat ccagccatgc
    30241 ttcgccctgg gtaatctctc catctaccgg tacgcgatcg ccggtcgtca ggcgcagcaa
    30301 catacctggc tgcacttccg ccagtggcac gcttttttca ccttcgtcag taaccaggcg
    30361 cgccgtcggc ggagttaaat cgagcaattt ctccagcgcc tttgaagaac gctgacgtgc
    30421 gcgcgcttcc agcatatgac cgagattaat cagaccgata atcatcgcac tggcttcata
    30481 gtaaagatgc cgcgcttcca tcgggaacca ctgcggccac aggttgacgc tcatcgaata
    30541 gagccacgcc acacccgttc ccagcgccac cagcgtatcc atcgtcgccg caccgttcag
    30601 caggcttttc catgcgctgc ggtaaaaatg cccgccggcg aaaaccatta ccgccagggt
    30661 tatcaggccg ataactaacc acaggctgcg gttgtcagcg gtgaccatca tgttatcgcc
    30721 gatcatcccc cagaccatca ccgggatacc caccgccagc gcgacaattg cctgccagcg
    30781 gaagcgcttc atcgtagcga cggcggtttc ttgctggcgc tcgcggcgtt tagcgtcatc
    30841 ttcaatcgct tccgcgccgt agcccgcttt ttccaccgcc tgcactaaat cttgtgggga
    30901 ggcactgccc atcaccagcg cagtacgctc cgccaggttt acccgtgcct gagtgacgcc
    30961 cggtacgctt tgcaacgcat tttgtacgcg ggtgacacag ctggcgcagc tcatgccgct
    31021 cagcagcaac tgctggctgt catcgtcatc ggcggtcgct gccggaagcg cctcagaaac
    31081 cgctgtcagt gcttccgacg ggattgatga ctccgccagc ggtttagcct ttgggtggct
    31141 tacagatgcg tcataacccg cttgtttgat ggtttcgatt agctgttctg cactggcagt
    31201 cccggtaacg tgcgcttcag tgatagacac atccgcctgt tcaacatccg ggcgctgttc
    31261 gagactttct ttcacgcgtt taacgcagtg accgcaggac aggccgtcca gggtcaggtc
    31321 gatagtttgt gacataaaac actcctttaa gacagttttg actggctgtg ataaaggtta
    31381 aaccttccag caaggggaag gtcaagaaat taataaacca ggcgggtaaa agtccgtaaa
    31441 gattaaaaaa tcggctcgat ttgcatcagg attagacatt tatctctttg ttttcctgta
    31501 gttaagttgc gggtgctaag ttaaatcagg atgcatgaaa atcggcaccg gggtgaggaa
    31561 ttacctcccg catctataaa aaggagttaa caaaagatgt tagatgcaaa caaattacag
    31621 caggcagtgg atcaggctta cacccaattt cactcactta acggcggaca aaatgccgat
    31681 tacattccct ttctggcgaa tgtccctggt caactggcgg cagtggctat cgtgaccagc
    31741 gatggcaacg tctatagtgc gggtgacagt gattaccgct ttgcgctgga atccatctcg
    31801 aaagtctgta cgttagccct tgcgttagaa gatgtcggcc cgcaggcggt acaggacaaa
    31861 gttggcgctg acccgaccgg attgcccttt aactcagtta tcgccttaga gttgcatggc
    31921 ggcaaaccgc tttcgccact ggtaaatgct ggcgctattg ccaccaccag cctgattaac
    31981 gctgaaaata ctgaacaacg ctggcagcga attttacata tccaacaaca actggctggt
    32041 gagcaggtag cgctctctga tgaagtcaac cagtcggaac aaacaaccaa cttccataac
    32101 cgggccattg cctggctgct gtactcagcc ggatatctct attgtgatgc aatggaagcc
    32161 tgtgacgtgt acacccgtca gtgctccacg ctcatcaata ctattgaact ggcaacgctt
    32221 ggcgcgacgc tggcggcggg tggtgtgaat ccgctgacgc ataaacgcgt tcttcaggcc
    32281 gacaatgtgc cgtacattct ggccgaaatg atgatggaag ggctgtatgg tcgctccggt
    32341 gactgggcgt atcgcgttgg tttaccgggc aaaagcggtg taggtggcgg tattctggcg
    32401 gtcgttcctg gcgtgatggg aattgccgcg ttttcaccac cactggacga agaaggcaac
    32461 agtgttcgcg gtcaaaaaat ggtggcatcg gtcgctaagc aactcggcta taacgtgttt
    32521 aagggctgat catgatgaac acggaaggta ataacggtaa caaacccctc ggtctatgga
    32581 acgtcgtttc catcggcatt ggggcaatgg tgggggcggg gatcttcgcg ctgctggggc
    32641 aggctgcgtt gctaatggaa gcctcgacct gggtcgcctt tgcttttggc ggtattgtgg
    32701 cgatgttttc cggttatgcc tatgcgcgtc tgggggcgag ctatcccagc aatggcggta
    32761 ttatcgactt ctttcgtcgc ggattaggca acggcgtttt ttcgctggcg ctctcgttat
    32821 tgtacctgtt gacgctggcg gtgagtatcg ccatggtcgc ccgtgctttt ggcgcttatg
    32881 ccgtgcagtt tttgcatgaa ggcagtcagg aggagcacct tattttgctc tacgcattgg
    32941 ggatcattgc ggtgatgacg cttttcaact ccttaagcaa ccatgcggta gggcggctgg
    33001 aagtgatcct cgtcggcatt aaaatgatga tcctgttatt gctgattatt gccggtgtct
    33061 ggtcgctgca accggcgcat atttccgttt ctgcgccccc cagctccggg gcgttcttct
    33121 cctgtatcgg gataaccttc cttgcctatg cgggctttgg catgatggcg aacgcggcgg
    33181 ataaagtgaa agatccggag gtcataatgc cacgggcgtt tctggtggcg attggcgtta
    33241 ccacgttgct ttatatctcg ctggcgctgg ttttgcttag cgatgtatcg gcattagagt
    33301 tagaaaaata tgccgatacc gccgtagcgc aggctgcttc tccgctcctc gggcatgtgg
    33361 ggtatgtgat cgtcgtcatc ggcgctttac tggcgacggc ttcagccatc aacgcaaacc
    33421 tgttcgccgt gtttaacatc atggacaaca tgggtagcga acgcgaactg ccgaagctaa
    33481 tgaataaacc tctgtggcgg cagagtacct ggggtaacat catcgtcgtg gtgttgatta
    33541 tgctgatgac ggcggcgctg aatttaggct cactcgccag cgttgccagt gccacctttt
    33601 tgatctgcta tctggcggtg tttgtggtgg cgatccgcct gcgtcatgat attcacgcct
    33661 cgttgccgat tcttatcgtt ggtacgttgg ttatgttgtt ggtgatcgtt ggctttatct
    33721 acagtctctg gtcccagggc agccgtgcgc tgatatggat tattggcgca ctcttactca
    33781 gccttattgt ggcaatggtc atgaagcgca ataaaaccgt ataacatctc tctgtgcgca
    33841 gtacctcctg tattattgtg gtggcggtcg atattcgcac tggcaaaaaa acgtgcttga
    33901 atatctgttg aaacccttta acaaagcaca ggaggcgttg cgcgaacgat gaacattagc
    33961 gatgtagcaa aaattaccgg cctgaccagc aaagccattc gcttctatga agagaagggg
    34021 ctggtgacgc cgccgatgcg cagcgaaaac ggttatcgca cctacacgca gcagcatctc
    34081 aacgaactga ccttactgcg ccaggcacgc caggtgggct ttaacctgga agagagcggc
    34141 gaactggtga atctgtttaa cgatccgcag cgtcacagcg ccgacgtcaa acgtcgtacg
    34201 ctggagaaag tagcggagat cgaacagcat atcgaagaac tgcaatccat gcgtaaccag
    34261 ctgctggcgc tggcgaatgc ctgccccggt gatgacagcg ccgactgccc gattatcgaa
    34321 aatctctccg gctgctgtca tcatcgggcg gggtgattaa ggcttgcgaa aatagtcgtc
    34381 cattattttc gttagctccg gacgttcccc gtcatcattg atggcaaaat ccagaaaaaa
    34441 agcatctgct tgcggcgttc ggttttgcgc catcaaccgg aaggtgaggg ggcctgacca
    34501 ggtttcggat gggctgatgt gcttatcagg gccgaaactc tcccatgcgc tgggcggtaa
    34561 tgttttgcac gcggtgagtt ttggtatgtg gtattgcagc tctgttttgt gcagacattc
    34621 cccgccagga aataccaggg tttgttgctc atcattaaaa tgggttgccg tgctgagcac
    34681 cagtgttttg agcggtcgcc cttccagcgc ggcggcagta gccttatggt gtccgtcgag
    34741 tagaacgcag agataggaat cagggagata ccaggccaga ccacgggcaa ttccagtttt
    34801 cgagagcaga caaaaaccgg gcggctccct gttcatcctc cgcaaaaccg ctgtagacaa
    34861 attccgcaca ggtagggcat ccagcctcgg accagaaacg tattaacggg acatcctgcc
    34921 agcagagcga atggataaga ccgtgcgagt gcggatcgta aatcacacat tgacgcagaa
    34981 atcctttccc ggacttcacc gaaaaaatga cgcccgcagc ggtatttttc agcagacgta
    35041 cttcaggttt tcgaaagggg gaaacatggc tactccttag ccgaacattc aattaacact
    35101 atgtgggggg ctatatgccg gatgcggcgt aaacgcctta tccggcatgg gttttggtac
    35161 agatttccag gtgtgataag acgcgtcagg cgatgaccgc acggataatc agcgttattc
    35221 cttctatcgc aatcacctca acatgcgtac cagcgccgag atcctcgctg gcgctgacag
    35281 gccatgaact gtcaccgacg cgcatatgac cgcgcccgtt gaccagcgga gattccagaa
    35341 caaaacgtcg gccaatcaac tgctgcccgc gctggtttaa atgactgtcg ctgtgctttt
    35401 gttcgcgcac ccgccgcgac aaccatttcc accacagcca ggcggcgagc agcgtcagga
    35461 cggcaaacat taccccttgc cactcccaac ccagcggcag caaccagacc accagaccgg
    35521 taatcaccgc tgccacgccg ctccacaaca gataaccatt gccgcccaac atctcggctg
    35581 ccagcagcaa accgccgaga cttagccaga aaatatgtgg atgaacgacc attaactcca
    35641 tcatggctga gtccgtttgt tggcgctgtc tttcaccagc tcagcaatcc cggcaatcga
    35701 ccccatcagg ctgctggcct ctaatggcat catcaccact ttgctgttac tggacgaacc
    35761 gatctgctgt aacgcttcgg tgtatttctg tgcgacgaag tagttcaccg cctgaatatc
    35821 accggaggcg atggcttcag acaccatttt ggtggcgcgg gcttctgctt cagcggaacg
    35881 ttcacgcgct tcagcctgta aaaacgccga ctgacgttcg ccttccgctt tcaggatttg
    35941 tgactgtttt tcaccttcgg ctttgaggat ttccgcctga cggatccctt ccgcttcaag
    36001 gatgtaagcg cgtttggtac gttccgcttt catctgcgcg ttcattgaag agataagctc
    36061 tgcgggcggg cgcacatcac gaatttcgat acgggtgact ttaatccccc acgggttggt
    36121 ggcctcatcg acaatatgca gcagacgcga gttaatgctg tcgcgctgag agagcatttc
    36181 atcaagttcc attgaaccca gcacggtacg gatgttagtc atggtcaggt tgatgatcgc
    36241 cagctccaga ttgctgactt cataagccgc gcgcggcgcg tcaatcacct gaataaagca
    36301 cacagcgtcg atggtaacgt tggcgttatc tttcgagata acttcctggg aagggatgtc
    36361 gagcacttgc tccatcatat tgatcttgcg accaatgcga tccataaacg gcaccaccag
    36421 gcttagacct ggctgtaacg ttttggtata gcgaccaaag cgttctaccg tccattgata
    36481 gccctgcggc acgattttga cgcccgcgcc gacaatgacc agcgcgacaa aaatgagaat
    36541 cgggataaag ataagcatcg gaaaaacctc ctgttgtacc gtccataatc agcaaaattg
    36601 ctgcttgatt aaacaaatta tacctgatta ctgaaagaga gttccccctt attcctgcga
    36661 aggataaact gtttttagta aaaatcagaa aaagggaaca gcgatgcagg aaaatagtcc
    36721 tttgcttcag ctacaaaacg taggatatct ggcgggtgat acgaagattc ttaataacat
    36781 caatttttcg ctgcgtgctg gcgaatttaa gttaattacc ggtccttctg gttgtggcaa
    36841 aagtacactg ctaaaaatag ttgcttcatt gatcagccca accagcggaa cgttactgtt
    36901 tgaaggtgag gatgtcagca cactaaagcc agaaatctac cgtcagcaag tctcttactg
    36961 cgcccagacg ccgacgctgt ttggcgatac ggtatacgat aacctgattt ttccctggca
    37021 gatccgtaac cagcagcctg acccggccat ttttctcgat tttcttgaac gcttcgcttt
    37081 accggacagc attttgacga agaatatcgc cgagctatct ggtggtgaaa aacaacgcat
    37141 ctcattgatt cgtaacctgc aatttatgcc gaaggtttta ttgctcgacg aaatcaccag
    37201 tgcgctggat gaaagtaata aacataacgt taatgagatg atccaccgtt atgtacgcga
    37261 gcaaaatatt gctgtgctgt gggtgacaca cgataaagac gaaattaatc atgcggataa
    37321 agtgattaca ctgcaaccgc atgctggaga aatgcaggaa gcacgctatg aactcgcata
    37381 atattactaa cgaatcatta gcactggcat taatgctggt ggtggtggca atcttaatta
    37441 gccataaaga aaaactggcg ctggagaaag atattctctg gagcgtcggg cgcgcgataa
    37501 tccagctgat tattgtcggc tatgtgctga agtatatttt cagcgtggat gatgccagcc
    37561 tgacattatt gatggtgtta tttatctgct ttaatgcggc gtggaacgcg caaaaacgca
    37621 gtaaatatat tgctaaagct tttatctcat cgtttattgc cattacggtc ggggcgggaa
    37681 ttaccctggc ggtactgatc ctctctgggt cgattgaatt tatcccgatg caggtgatcc
    37741 ctatcgccgg gatgatagcc ggtaacgcca tggtagcggt ggggttgtgt tacaacaatt
    37801 tagggcaacg ggtcattagc gaacagcaac agattcagga gaaactgagt cttggcgcga
    37861 cgccgaaaca ggcttcagcg atattgattc gcgacagtat tcgcgcggct ttaattccga
    37921 cggtcgattc agcaaaaacg gtaggcttag tgagtttacc aggaatgatg tccgggctga
    37981 tatttgccgg gattgatccg gtgaaggcga ttaaatatca gattatggtg acctttatgc
    38041 tgctctcaac cgccagcttg tcgaccatta ttgcctgcta tttaacctat cgtaagtttt
    38101 acaattcgcg ccaccaattg gtggtgacgc aattgaagaa gaaatgatgc gatgccggat
    38161 gcgtcttatc agacctacat ggcacctgca atgtattgaa ttagcacggt ttggtaggcc
    38221 ggataaggcg ttcacgccgc atccggcggc tatgcgcgga tgcctgatgc gacgctggcg
    38281 cgtcttatca ggcctacaaa ccagcacagc atcgcatttc aacggaaaat caatacaaca
    38341 acgcatacag ctggcggcga tacttcgacg ccagtgcatc acccgtaccc agcgcagcga
    38401 ggatctcctg gaatgtttta cgtgtctgac catctgcggc ggtgagatct ttacgcagat
    38461 gcccaaacag taactccagc gcctcttcat tgcgcccaac ctggtgcagt tgcagtgcca
    38521 gttgcgtcgc cagtgcggca tcttctggat tctccgccac ctgctgttgc aactgttgaa
    38581 tttccggcgt atcagccgcc tgcttcagca gttcgatttg cgccaccagc ccctgatagc
    38641 gggtgtcctg atcctgcaac ggaatggttt tcagcacggc ttctgcatct tcagaacggt
    38701 tcagcgcaat cagcgtttct gccaacagca ggccgatttc cccgttctga ttcgacaact
    38761 gccaggcgtc tttcagcaat ggcagggcgt cggtgtaatt gccttcctgc atcagttgca
    38821 tcgcctgctg cgctttcagc tcttcttcac gcggcagcac tttatccagc agggcgcgga
    38881 tcgcctcttc cggttgcggc ccctggaagc cgtctactgg ttgcccgttc tggaacagat
    38941 atacggtcgg aatcgcgcgc agaccaaact gggcggcaat catctgctcc gcgtcgcagt
    39001 ccagcttcgc cagaataaat tgcccgttgt actgcgccgc gaggctttcc agaattgggg
    39061 ttaactgcaa acagtgctgg ctacgttcag accaaaaata gaacagcacc ggagtggtca
    39121 tcgactgttc aagaacctgt tgcaggttag attcgttaat gttgacaata ttttctacgg
    39181 acatggagtc gctctctgtt gtcgatattt tctttgacat gggggcttaa gcgcgcgctt
    39241 caactcaccc ctgcaatatt ttgtccatca cgcgccccgg cagcaggcgc ttaagcacca
    39301 ttaccgccct ggtcaccagc gtcaccggat agcgcatctt cggcttctcg ctaataaaag
    39361 catggcgcac tttgccgacc accgcttccg gtcccaacgt aaagcgggcg gcgatgccag
    39421 gattttcgac tggtttatca ctttgcgtct ggttgacgtt gtcggtgaag cgagtacgaa
    39481 tgggaccagg ttcgatcagg ctgactttaa ttccgctgtg gcgcagctcc atgcgcagtg
    39541 cgtctgacca cgcctccagc gcatatttac tggccgcgta agcgccacga cccggtgtgg
    39601 agattaatcc catcaccgat gaggtcatca caatacgccc ttcacggtgc ggcaacatcg
    39661 cgggtaacag gcgcatggtg agctggtgtg cgccgaaaaa gttagcggaa aactgctgtt
    39721 ccatctgcgc acggctgatg gtggaaaggg ggccatacat gccgaatccg gcattgttaa
    39781 agatcccata cagacaatta tcggtcaggg cgatcacttc gtcggctgcg cgatcaacac
    39841 tttctggcga atccagatcg atcaacacgc cggtaaatcc catgctgttc atgcgctcaa
    39901 catcatccgg tttccggcaa cctgccagca catgaaaacc ctggcgtttt aattcgagtg
    39961 cgctttccag gccaatacca ctggaacatc cggtaattaa gaccgatttt tgcataactt
    40021 tacctgtcag gatctccgtt gctttatgag tcatgattta ctaaaggctg caactgcttc
    40081 gccatccagt cggcaataaa cggctgggcg tcgcggttgg gatgaatacc gtcatcctgc
    40141 atccattgtg gcttgaggta gacctcttcc ataaaaaagg gcagcagcgg aacatcaaac
    40201 tctttggcga gtttggggta aatggcgcta aaggcttcat tataacggcg accatagttt
    40261 gcaggcagac gtatttgcat taacaatggt tcagcgttgg cggctttgac atcctgcaaa
    40321 atctggcgca gcgtttgctc ggtttgctgt ggctgaaaac cacgcaaacc gtcattgccg
    40381 cccagttcaa ccagcaccca gcgcggctga tgctgtttca gctgagccgg aaggcgcgcc
    40441 agcccttgtt gcgaggtgtc accgctgatg ctggcattga ctaccgacgt tttactctgc
    40501 cacttatcat tcaacaaggc aggccaggcc gcgctggcag acattcgata cccggcgctc
    40561 aggctatcac ccagaatcaa taacgtgtcc gctgcggcgg cacggaaggt taacaggacc
    40621 aggaacagga agggcaaatg ccagcggaaa acattgttga agttcatcat cttaagaagt
    40681 ccgtcggtca gggggagcat gaactctcca tcctcaccgg agttgagctg gttgtcaaac
    40741 gtggcgagac catcgcactg gtgggcgagt cgggatcggg taagtcaacc ttgctggcga
    40801 tcctcgccgg gctggatgac ggcagcagtg gcgaagtgag tctggtggga caaccgctac
    40861 ataatatgga cgaagaagcg cgggcaaagt tgcgcgcgaa gcacgtaggc tttgtttttc
    40921 agtcatttat gttaattcct acccttaacg cgctggaaaa cgtcgagctt ccggcgctgc
    40981 tgcgcggtga gagtagcgca gaaagtcgta acggggcgaa agcgttgctc gaacagttag
    41041 ggctgggtaa acgtcttgat catcttccgg cacagctttc tggcggcgaa cagcaacgag
    41101 tggcgctggc gcgagccttt aatggtcgac ctgatgtgct gtttgccgac gaacccaccg
    41161 gtaaccttga ccgccagacg ggcgataaaa ttgccgatct gcttttttcc ctcaaccgtg
    41221 agcatggcac cacgttgatt atggtgaccc acgacctgca actggcggca cgctgtgacc
    41281 gctgcttacg gctggtgaac gggcagttgc aggaggaagc atgattgcac gttggttctg
    41341 gcgcgaatgg cgctcgccgt cgctattaat tgtctggctg gcgcttagcc tggcggtggc
    41401 ctgcgtgctg gcgctgggca atatcagcga tcgcatggag aagggcttaa gccagcaaag
    41461 ccgtgagttt atggcgggcg atcgggcgtt gcgcagttcg cgcgaagtgc cgcaagcatg
    41521 gctggaggaa gcgcaaaagc gcggcctgaa agttggcaag cagctgactt tcgccaccat
    41581 gacctttgca ggcgacacgc cgcaactggc gaacgtcaaa gcggtggatg atatctaccc
    41641 gatgtatggc gatctgcaaa ctaatccccc tggcctgaaa ccgcaggcgg gcagcgtatt
    41701 gctggcccca cgcctgatgg cactgcttaa cctgaaaacg ggcgatacca ttgacgtggg
    41761 cgatgccacc ttgcggattg ccggagaagt gattcaggaa ccggattccg gttttaatcc
    41821 tttccagata gccccacgcc tgatgatgaa tctggcggat gttgataaaa ccggagccgt
    41881 gcagccgggg agtcgggtca cctggcgtta taaattcggc ggcagcgaga accagctcga
    41941 cggctatgag aaatggttgt taccccagct taaacccgaa caacgctggt acggtctgga
    42001 acaggacgaa ggcgcgctgg ggcgatcgat agaacgttcg caacagttcc tgctgctttc
    42061 ggcgcttctg accttgctgc tggcggtggc ggcggtcgcg gtggcgatga atcattactg
    42121 tcgcagtcgc tacgatctgg tggcgatcct caagacgctg ggggcagggc gagcgcaact
    42181 gcgtaagtta atcgtcggtc agtggttgat ggtgctggta ctttcagccg ttaccggtgg
    42241 ggcgataggc ctgttgttcg aaaacgtgtt gatggtgctg ctcaagcccg ttctgcctgc
    42301 tgcactaccg ccagccagcc tctggccgtg gctgtgggcg ctcggcacca tgacggttat
    42361 ttcgctgctg gtggggctac gaccataccg cctgttgttg gcaacgcagc ctttacgcgt
    42421 attacgtaat gatgtggtag cgaacgtctg gccgctgaag ttttatctgc cgattgtcac
    42481 cgtggtggtt gtgctactgc tcgccgggct gatgggcggc agtatgctgc tctgggcggt
    42541 gctggcgggc gcggtagtac tggctttgct gtgcggtgtc ctgggctgga tgctgctgaa
    42601 tgtacttcgc cgcatgacgc tgaaatcgct acctctgcgc ctggcggtta gccgcctgtt
    42661 acgtcagccg tgggcgacgt tgagccagct ttcggcattt tcgctctcct ttatgctgct
    42721 ggcactgttg ctggtgttgc gtggcgatct gctcgaccgc tggcaacagc agctaccgcc
    42781 agaaagtcct aactactttt taatcaacat cgctacggaa caggttacgc cgctgaaagc
    42841 gtttctcgcg gaacatcaga tagtcccgga atcgttttat ccggtggtgc gggcgcggtt
    42901 gacggcgatt aacgacaagc cgacagaagg caatggagat gaggcgctca accgcgagct
    42961 gaatctcacc tggcaaaata cgcggcctga tcataacccg atcgtcgccg gtaactggcc
    43021 gccaaaagcc ggtgaagtgt cgatggaaga ggggctggcg aaacgcttaa acgttgccct
    43081 cggcgatacc gtgactttta tgggcgatac ccaggagttc cgcgctaaag tgaccagcct
    43141 gcgcaaagtg gactgggaaa gtctgcggcc taatttctat tttattttcc cggaaggggc
    43201 attagacggg caaccgcaga gctggcttac cagtttccgc tgggagaatg gcaacggcat
    43261 gttgacgcaa ctcaaccgcc agttcccgac cattagcctg ttagacattg gcgcgatttt
    43321 aaaacaggtc ggtcaggtgc tggagcaggt aagtcgggcg ctggaagtga tggtggtgct
    43381 ggtcaccgcc tgcggtatgt tgctgttgct ggcacaggtg caggtgggaa tgcgtcagcg
    43441 tcatcaggag ctggtggtgt ggcgcactct cggtgcgggc aaaaaactgc tgcgcacgac
    43501 attgtggtgt gagttcgcca tgctcgggtt tgtatccggc ctggtggccg caattggtgc
    43561 ggaaacggca ctggcggtac tgcaatcgaa agtgtttgat ttcccgtggg agccagactg
    43621 gcgattgtgg attgtgctgc cgtgcagcgg tgcgctactg ctgtcgcttt gcggcggctg
    43681 gctgggtgcg cgactgctta agggtaaggc gctattcagg cagtttgtgg ggtgatgtga
    43741 taaagccgtt tatttctacc tggtagataa acggctttat tattagtgca tcacgtaatt
    43801 aaaaaaatgt tatgcccaaa c
//
LOCUS       DAPOXO010000036        43553 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPOXO010000036 DAPOXO010000000
VERSION     DAPOXO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43553
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.036"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            213..455
                     /locus_tag="ROH59_002354"
     CDS             213..455
                     /locus_tag="ROH59_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804829.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            570..1208
                     /locus_tag="ROH59_002355"
     CDS             570..1208
                     /locus_tag="ROH59_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HDX4804830.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGATWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            1205..1942
                     /locus_tag="ROH59_002356"
     CDS             1205..1942
                     /locus_tag="ROH59_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HDX4804831.1"
                     /translation="MIKQTIVALILSVGASSVFAAGTVKVFSNGSSDAKTLTGAEHLI
                     DLVGQPRLANSWWPGAVISEELATAAALRQQQALMTRMAELAADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQS
                     FTPGRDVASYLSDQSLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETPDALNADILQTLTQRIPQ"
     gene            1942..4038
                     /locus_tag="ROH59_002357"
     CDS             1942..4038
                     /locus_tag="ROH59_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HDX4804832.1"
                     /translation="MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPT
                     ARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTY
                     KDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
                     LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQAKGDTLYVTGE
                     QVKYRDPREGIIRANRIVMNDLPDGIKTIRITENRLNMPQVTTETDVASLKNHLAGEP
                     LGHETKLAQKRVEPVVPKSTEQGWYIDKSRFDFHIDPVLNQSIGGPENFYMYQLGVMG
                     TADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQHLGNGFYGQVYGGYLETMFGGVGAEVLYRPLDSNWAFGLDANYVKQRDWRSA
                     KDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFQLYDMTSDRSVNFR"
     gene            complement(4085..4363)
                     /locus_tag="ROH59_002358"
     CDS             complement(4085..4363)
                     /locus_tag="ROH59_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804833.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            4578..4988
                     /gene="psiE"
                     /locus_tag="ROH59_002359"
     CDS             4578..4988
                     /gene="psiE"
                     /locus_tag="ROH59_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HDX4804834.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            complement(5082..5972)
                     /gene="malG"
                     /locus_tag="ROH59_002360"
     CDS             complement(5082..5972)
                     /gene="malG"
                     /locus_tag="ROH59_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HDX4804835.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            complement(5987..7531)
                     /gene="malF"
                     /locus_tag="ROH59_002361"
     CDS             complement(5987..7531)
                     /gene="malF"
                     /locus_tag="ROH59_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HDX4804836.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKIYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGT
                     LTNNQSGVKYRPNDQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            complement(7685..8875)
                     /gene="malE"
                     /locus_tag="ROH59_002362"
     CDS             complement(7685..8875)
                     /gene="malE"
                     /locus_tag="ROH59_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HDX4804837.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFETDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYQ
                     DELAKDPRIAATMDNAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALKDAQT
                     RITK"
     gene            9240..10355
                     /gene="malK"
                     /locus_tag="ROH59_002363"
     CDS             9240..10355
                     /gene="malK"
                     /locus_tag="ROH59_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HDX4804838.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            10427..11767
                     /gene="lamB"
                     /locus_tag="ROH59_002364"
     CDS             10427..11767
                     /gene="lamB"
                     /locus_tag="ROH59_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HDX4804839.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYTGSSSTNPYYGKAVSADFNGGSFGRGDSDEWTFGAQMEIWW"
     gene            12000..12920
                     /gene="malM"
                     /locus_tag="ROH59_002365"
     CDS             12000..12920
                     /gene="malM"
                     /locus_tag="ROH59_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HDX4804840.1"
                     /translation="MKMNKSLIALCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLSTGGQQLNVSGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSVPDIPDPIARHTTDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAAPAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            13099..13596
                     /gene="ubiC"
                     /locus_tag="ROH59_002366"
     CDS             13099..13596
                     /gene="ubiC"
                     /locus_tag="ROH59_002366"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HDX4804841.1"
                     /translation="MSHPALTQLRALRYFTEIPALEPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            13609..14481
                     /gene="ubiA"
                     /locus_tag="ROH59_002367"
     CDS             13609..14481
                     /gene="ubiA"
                     /locus_tag="ROH59_002367"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HDX4804842.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARTLFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(14636..17059)
                     /gene="plsB"
                     /locus_tag="ROH59_002368"
     CDS             complement(14636..17059)
                     /gene="plsB"
                     /locus_tag="ROH59_002368"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HDX4804843.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTKQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            17230..17598
                     /gene="dgkA"
                     /locus_tag="ROH59_002369"
     CDS             17230..17598
                     /gene="dgkA"
                     /locus_tag="ROH59_002369"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDX4804844.1"
                     /translation="MANNTTGFIRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            17708..18316
                     /gene="lexA"
                     /locus_tag="ROH59_002370"
     CDS             17708..18316
                     /gene="lexA"
                     /locus_tag="ROH59_002370"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HDX4804845.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            18389..19714
                     /gene="dinF"
                     /locus_tag="ROH59_002371"
     CDS             18389..19714
                     /gene="dinF"
                     /locus_tag="ROH59_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HDX4804846.1"
                     /translation="MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVY
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
                     IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGI
                     SGEMLKTAWRGNFRHLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGE
                     HIIALLTSLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAA
                     GFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNDTWFVAT"
     gene            19830..20039
                     /locus_tag="ROH59_002372"
     CDS             19830..20039
                     /locus_tag="ROH59_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDX4804847.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVDSWEKRHDYRW"
     gene            complement(20081..20596)
                     /gene="zur"
                     /locus_tag="ROH59_002373"
     CDS             complement(20081..20596)
                     /gene="zur"
                     /locus_tag="ROH59_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HDX4804848.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALEFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCSACVEVEACRHPEQCHH
                     DHSIQVKKKPR"
     gene            20752..21747
                     /gene="dusA"
                     /locus_tag="ROH59_002374"
     CDS             20752..21747
                     /gene="dusA"
                     /locus_tag="ROH59_002374"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HDX4804849.1"
                     /translation="MPAESHTVYPAYRFSIAPMLDWTDRHCRYFLRLLSRNTLLYTEM
                     VTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEARGYDEINLNVGCPS
                     DRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYEFLCDFINTV
                     SGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKSL
                     EEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPVAVVRAMYPYIEREL
                     SQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVLEHALKLVADKR"
     gene            21881..22123
                     /gene="pspG"
                     /locus_tag="ROH59_002375"
     CDS             21881..22123
                     /gene="pspG"
                     /locus_tag="ROH59_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HDX4804850.1"
                     /translation="MLELLFVIGFFVMLMVTGVSLLGIIAALIVATAFMFLGGMLALM
                     IKLLPWLLLAVAVVWVIRAIKAPKVPKYQHYDRWRY"
     gene            complement(22288..23271)
                     /locus_tag="ROH59_002376"
     CDS             complement(22288..23271)
                     /locus_tag="ROH59_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HDX4804851.1"
                     /translation="MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVKNKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSMHNIN
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREENLVERLKEITGGKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDARRAHEILESRATQGSSLLIP"
     gene            complement(23377..25413)
                     /locus_tag="ROH59_002377"
     CDS             complement(23377..25413)
                     /locus_tag="ROH59_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDX4804852.1"
                     /translation="MIDETLTALTDIKMPHYAPLAQASGSIDLNGTILPEYCCNTLVL
                     GSGAAGWRAAVELKRQNVDVMVASSKAFWGTSACSGSDKQTLHTANTRANGDHFLTLS
                     NTLAAGGAMDHDTAYVEAVGSVNTCEVLKYLGLDLPEDLFGATLRYQTDHDEFGRATS
                     CGPRTSRLMVKVLAQEAMRLNIPLCDHTTAIHILTSGEGENRRVVGVIAIDKACRDNP
                     WRMVVIRCQHLVLATGGPGELYRDSVYPVNCFSALGMALEAGITLVNLTESQFGIGTP
                     RSQFPWNLSGTYMQAMPRIYSQDHSGRQYNFLAAYYPTTRMLASAIFRKGYQWPFHAE
                     RMLEYGSSLLDVAVYEETQKGRDVFLDFLREPEPAADGTSFNLQELDDDVIDYLQQNH
                     ALLAQPLARLTQMNPLAIRLYQMHGHDLTASPLKFTLNNQHLNGGIEVDIWGRTSLTG
                     CYAAGENAGTHGVTRPGGAALNAGQVFARRCALHIAHQKSQDRPLERQQILSTINEAQ
                     QYLNQGLLRDDVRETIQNTMSHHAAILCHTQGINTAAQTLATLCEDIRREGIQCDENS
                     LAQSFQWRQSAQLALAVLRSLQCYVENGGGSRGARAIYDGEAGIAPQTPGGPLLAWRF
                     RPENQDARQYMICVCREANDYQTWTRPCRERGVLTLTNFERQWQNWIAATPFQY"
     gene            complement(25424..26704)
                     /locus_tag="ROH59_002378"
     CDS             complement(25424..26704)
                     /locus_tag="ROH59_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001057569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDX4804853.1"
                     /translation="MNMTTSVPQTPSLFRRIMTKLAAFAPGIFLIGYSIGTGSITTMA
                     KAGANYGVSLMWAVALSCIVTWFLIRIYGRYASVTGERALTAFRRHIHPGVAMLFLIG
                     LTVAVSGSIMGVMGILADVMATWSTTWFSGGISALAWAIAMVIMINVMLWTNSNAGFD
                     KILSALVGIMGLAFVINFFIMMPPVADLLAGFIPSVPDPVAGDNSTPFLIISGMVGTT
                     VAPAMFLMRTTLVKSNGWGVDNLPHQNRDAIVSAGMMFIISAAVMAAAAGTLYQTGTG
                     LNNASQMVIILEPIAGSAAVGLFVIGIVAAGLSSQFPNLLLTPWLLADWRDTSNEVSP
                     GYRILMTVMSLLCLVVPLFHARPVLVMIASQAFNAIILPLTVLCMFWLANKPSLMGKY
                     RCSRWENVMFIAISVFTLIMGYMAMSGLIESLMK"
     gene            complement(26731..27510)
                     /locus_tag="ROH59_002379"
     CDS             complement(26731..27510)
                     /locus_tag="ROH59_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDX4804854.1"
                     /translation="MNNGTIDLQRNGFIATLVINRPAKLNALTPEMLEQLLAHCHTLE
                     TDSEIRVVLLTSASEKAFCVGADIHRWTSLSALDMWRNWIRRGHQAFDALAQLPQPVI
                     ALLHGLAYGGGLELAATADIRICSAEAQMALPETGLATVPGWSGTQRLTALLGRSLVK
                     ELVFTGEPLDAQRALSCGLVNRVVAREALHDAGLQLAQRIAQRAPVAVQIAKQVIDAG
                     EGIAVASTLEALAGAFSATTEDAHEGSQAFTEKRQPHFQAR"
     gene            complement(27503..29074)
                     /locus_tag="ROH59_002380"
     CDS             complement(27503..29074)
                     /locus_tag="ROH59_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDX4804855.1"
                     /translation="MCSVRTITAPEAADLIVDGAVVTVSSSSGMGCPDAVLAAIGERF
                     QRAGHPQNITSIHPIAAGDMYGVKGIDHLAQPGLLAKVIAGSYPSGPSSMTPPLIWQM
                     INDNAIPAWNLPSGILFDMHREAAAHRPGVLTQTGMDTYVDPLLQGGAMNEKAAQQSL
                     VERVRFANDDWLFFPSIVPQVAIIRATTADERGNLTYEHEGAYLGPLEQATAVRNNGG
                     IIIAQVKRQVAAGSLKPKEVRIPGVLVDYIVIAPEQTQTTQTQYEPAISGEISRPLSA
                     FRYMEHGPARVIAQRVAQELQSGDAVNIGFGISANVPRILLEQGRHGDVTWLLEQGAI
                     GGVPLLEFQFGCASNAEAFLPSPQQFTYFQGGGFDLTLMSFLQIGADGSVNVSHLPAR
                     PHVTAGCGGFIDITSHAKRIIFSGFFNAGAQLQLEEGQLRIIKEGKAKKLVQDVAHVT
                     FSGKRAIRLGQQVQYITERCVLELTPDGLLVTEIAPGIDPERDILAQSDAPLRLADDL
                     KLMNPLYFQQGSHHE"
     gene            29330..30364
                     /locus_tag="ROH59_002381"
     CDS             29330..30364
                     /locus_tag="ROH59_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX4804856.1"
                     /translation="MAKSDTGRKRVTLTDVARAAGVSKSTVSLVLNDSSLIKKETQQK
                     VQQAIEQLGYVYNRFAANLRSQKSLTIGVVIDDLINPFFAEFTMGLEMTLAEHGFITV
                     MSNTSQRSDRQKQVLDTLLEHHVAGIVLCPVNSTSEADLQRYANSSTPLLITMRPLDW
                     QQLPVDYVGVDSHAGVREATEYLIQQGHRDIVFIGGLTHHMRYQGYLEAMNHHGLQPW
                     STDAFSLRAEPTQANGYQLMQQLLDMPSPPTAVICYNDLMAFGAESALGERGLFAGED
                     ISLIGNDGVAACAYSNPPLTTIAVEPLALGKQAAQQILRRIAQPDAPLSHYIYRPTLQ
                     IRASTGKRGR"
     gene            30437..31852
                     /gene="dnaB"
                     /locus_tag="ROH59_002382"
     CDS             30437..31852
                     /gene="dnaB"
                     /locus_tag="ROH59_002382"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDX4804857.1"
                     /translation="MAGNRPFNKQQTDNRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            31905..32984
                     /gene="alr"
                     /locus_tag="ROH59_002383"
     CDS             31905..32984
                     /gene="alr"
                     /locus_tag="ROH59_002383"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDX4804858.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEANLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGAPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            33007..33564
                     /locus_tag="ROH59_002384"
     CDS             33007..33564
                     /locus_tag="ROH59_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HDX4804859.1"
                     /translation="MSYSEIAACLAYAVSVWLAARNNVHTWWIGIIGSILYGWVFWSV
                     QLYADVTLQLFFIVTSITGWIHWLKGQGGDILPVRRTQASHFFLLLLCAVVVAGGYGF
                     LLHTFTNAWAPWLDSLILTFSVLAQFMLMGRRIENWYVWLAVNTLAVPLYMTRGLNLT
                     AGLYFLFWINAWYGLYQWRKELQTS"
     gene            33561..34565
                     /locus_tag="ROH59_002385"
     CDS             33561..34565
                     /locus_tag="ROH59_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX4804860.1"
                     /translation="MKPFATGLVVGKFAPLHCGHEKLINTALAQCEELFIISYSVPEM
                     PDCEPEKRLTWLQVRFPQATFLVLTPELVARYNLPAIPHNNADADIHRHYVATLCLQI
                     LRCRPHAVFTAEDYGDGFANVLARRFAQPVEHVRMARPVGDEAPSGTLIRSDVHRYRY
                     MLANDVYYSFVRRICLLGGESTGKSTLSKALAGVLDTVYVAEFGRDYWEEKNGILTAD
                     DLLHIACEQVRREQQAEANHYLICDTSPLTTLFYALDQYGHAPQELHQLAEREYSLVV
                     LCGAEFPFVQDGTRQGEVFRARQQVWYEQELSRRNIPYLSVSGPLQERVEQILRQLPD
                     "
     gene            34647..35840
                     /gene="tyrB"
                     /locus_tag="ROH59_002386"
     CDS             34647..35840
                     /gene="tyrB"
                     /locus_tag="ROH59_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HDX4804861.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLKAVADAEARLNAQPHGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTL
                     GGSGALKVGADFLKRYFPESSVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNEQWDAVIEILKARELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLVEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDQLREEFGVYLIASGRMCVAGLNTQNVHRVAKA
                     FAAVM"
     gene            36022..38766
                     /locus_tag="ROH59_002387"
     CDS             36022..38766
                     /locus_tag="ROH59_002387"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001468317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HDX4804862.1"
                     /translation="MENMTSPGTLLSGDNATWLEEYYQTWLRTPEQLPEDWRRFFLSP
                     ELTVQSVSGDNNISGATLKKQAAVIQLINAWRTQGHLRAKLDPLGLNPPADVPSLQPG
                     FWGLSEEDLLQEFSVTFGAHTTQMPLKQLLNLLEQAWASSQAYELAHLENREEINWLL
                     SRIESSNAPQADAQTCIARFEKLMAAETLERYLHTRYVGQKRFSLEGGESAIPALDTL
                     TKRLRAQGVEEMVIGMAHRGRLNVLVNLLNKDPAQLFAEFEGKQTIGSGSGDVKYHMG
                     YSSNLETPAGSLHVALAYNPSHLEIVNPVVLGQVRARQERRGEDGQAKVVGVLIHGDS
                     ALGGLGVNQTTFNLSQTQGYGTGGTLHLVINNQIGFTTSRLQDMRSSRYCTDIAKMVA
                     APIIHVNGDDVDAVCQVMELACEWRDTFRRDIIIDICCFRKHGHNESDEPRLTQPQMY
                     QAVDAHPGTLARYGESLARRGLLTQAQQDEMTARYRDWLDSCQKREPQPLKPAIHSFS
                     ANWYGLTNPHWSAPVSTALPRQKLAAYGEIISTLPPDVVAHPTIKRQLALRQDMAAGT
                     QPVDWGMAEMLAYASLVDAGVGVRLSGEDSGRGTFSHRHAVVHHQTEARRYLPLQHIR
                     AGQASFDVYDSVLNEEALLAFEYGYSTSAPQQLVIWEAQFGDFANGAQVAIDQFISSG
                     ETKWDRYSGLTILLPHGYDGQGPEHSSARPERWLQLCAENNMQVVMPSESAQMFHLLR
                     GQALRPMRKPLVIMMSKRLLRFKGAMSELCEFTDDAYKPVITDPQLHQSQKVKRVILC
                     SGQVYYDVLEARKQREHEDEVAIVRLEQLYPFPVAELNDVLASWPNCCEWIWLQEEPE
                     NQGAWRQIRHELAALKINTPYWQYAGRPAAAAPATGYGRVHKQQIDEFLAAAFADIQP
                     "
     gene            38799..39953
                     /gene="odhB"
                     /locus_tag="ROH59_002388"
     CDS             38799..39953
                     /gene="odhB"
                     /locus_tag="ROH59_002388"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001468318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HDX4804863.1"
                     /translation="MIEITVPVLPESVTEGTLTTWCKQEGEHVKRDDVIAELETDKVI
                     LEIPAPHDGVLSNIIVSEGSTVTSAQLLAHLKPQAVIEETVTPVTETLAMPSARLEAQ
                     RSGVELADVAGSGRNGRILKEDVQRVTPAPAIQPERVAEIAPAKPLTPGARQERREPM
                     SRLRQRIAERLLASQQNNAILTTFNEVNMQSVMDLRARWKDRFAEKHGVKLGFMSFFV
                     KAVTRALERFPVVNASVDGNEIIWRDYCDIGIAVSSNRGLVVPVLRNAQSLSLVEIER
                     QIAEYATQARNGKLPLEALQGGTFSITNGGTFGSMMSTPIINPPQSAILGMHAITPRP
                     VAENGQVVIRPMMYLALSYDHRIIDGQEAVHTLVAIRELLESPEQLLLDL"
     gene            39965..41384
                     /gene="lpdA"
                     /locus_tag="ROH59_002389"
                     /pseudo
     CDS             39965..41384
                     /gene="lpdA"
                     /locus_tag="ROH59_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000103914.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
     gene            41406..42575
                     /gene="sucC"
                     /locus_tag="ROH59_002390"
     CDS             41406..42575
                     /gene="sucC"
                     /locus_tag="ROH59_002390"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HDX4804864.1"
                     /translation="MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKG
                     AVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLGSQLVTYQTGPEGQYVSSILLCE
                     NIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
                     CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAK
                     VSLDDNALYRHPELQVLRDETQEDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATM
                     DIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVNIFGGIVRCDMIARA
                     IIHALNEASITLPVVVRLSGNNAAEGQRLLAESGLTVEAVDSLDDAAKRIIALLN"
     gene            42588..43460
                     /gene="sucD"
                     /locus_tag="ROH59_002391"
     CDS             42588..43460
                     /gene="sucD"
                     /locus_tag="ROH59_002391"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HDX4804865.1"
                     /translation="MSVLINKHTRVLVQGITGKNGTFHTEQAIAYGTQIVGGVTPGKG
                     GQRHLDRPVFDSMKDAMRQTEADASVIYVPAPFVLDSVVEAIEAGVKLVVVITEGVPT
                     LDMVKVRRLLDCHPDVRLIGPNCPGVITPGECKIGIMPGEIHRPGRIGIVSRSGTLTY
                     EAVAQTTALGLGQSTCIGIGGDPVPGTNFIDALRLFENDPQTDAVIMIGEIGGNAEER
                     AAEFIRHDMNKPVVGYIAGVTAPKGKRMGHAGAIISGGSGSAEDKFRAFDKAGMAWTR
                     NPALLGETLWNVIK"
BASE COUNT        10340 a        10942 c        11766 g        10505 t
ORIGIN      
        1 gcagagtaat tactttttat tttattttaa cttcatgatt tttaatctta tttatatata
       61 agtcaaagct tatatttgat attcattcca attgtcctaa aactccatca ctaattcccc
      121 gcgccgtaat tcgcatgctt tagttgtgta tactcgatcc cgcccgaaat gttttgggta
      181 aatctccatt cattcaatga agggaaattg ttatgaaaaa agttctgtat ggcatttttg
      241 ccatatctgc gcttgcggcg acttctgcgt gggctgcacc tgtacaggtg ggcgaagcgg
      301 caggatcggc agcaacgtcg gtttcggcgg gtagttcctc cgcgaccagc gtcagcaccg
      361 taagctcggc ggtgggtgtc gcgctcgcgg caaccggtgg cggtgatggt tctaataccg
      421 ggaccaccac aaccacgacc accagtaccc agtaataaag tatgtatccc caaaataatt
      481 cgagtcatcg catctgaagc ttgaagtatg aaggggatta accataacca cactccggtg
      541 tggttattct gcccctctgg agaagagtcg tgaagcgacc agcactcatt cttatctgcc
      601 tgctattaca ggcctgttca gccacgacta aagagctggg caattcactg tgggacagtc
      661 tgttcggtac gccaggcgta cagctgacgg acgatgatat tcaaaatatg ccctacgcca
      721 gccagtacat gcagcttaat ggcgggccgc agttatttgt ggtgctggcc ttcgctgaag
      781 acggacaaca aaaatgggtc actcaggatc aggccaccct tgtcacacaa catggtcgtc
      841 tggtgaagac tttgcttggc ggcgacaacc tgattgaagt gaataacctt gccgccgacc
      901 cgctgattaa acccgcacaa attgttgatg gtgcaacctg gacgcgcacg atgggctgga
      961 ccgagtacca gcaggtacgc tacgccaccg cacgctcagt cttcaaatgg gatggcaccg
     1021 ataccgtcaa agtcggcagc gatgaaaccc cggttcgcgt gctggacgaa gaagtctcca
     1081 ccgaccaggc gcgctggcat aaccgctact ggatcgacag cgaagggcaa attcgccagt
     1141 cggaacagta tctcggcgcg gattacttcc cggtgaaaac caccctcatc aaggcggcaa
     1201 aacaatgatt aaacaaacta ttgtcgcatt gattttgagt gtgggggcgt catcggtctt
     1261 cgcggcggga accgtcaagg tattcagcaa tggcagcagt gatgccaaaa cgctgacggg
     1321 tgcagagcat ttaatcgatc tggtaggcca accgcggctg gcaaacagct ggtggcctgg
     1381 tgcggtgatt agcgaagagc tggccacggc ggcagcattg cgtcagcagc aggcgttgat
     1441 gacacggatg gcagaactgg ccgcagactc cagcgccgac gatgccgccg caattaacgc
     1501 cttacgccag caaattcagg cgttgaaagt gacgggcagg caaaaaatca atcttgatcc
     1561 tgatatcgtc cgcgttgccg aacgcggtaa cccgccgttg cagggcaact acacgctgtg
     1621 ggtcggaccg ccgccgtcca cggtcacgtt gttcgggctt atcagtcgtc ctggcaagca
     1681 gtcattcact ccaggtcgcg acgtggcgag ctatctctct gaccagagcc tgctcagcgg
     1741 tgcggatcgc agctacgcgt gggtggttta cccggacgga cgcacgcaaa aagcgccggt
     1801 ggcttactgg aacaagcgtc acgtagagcc gatgcccggc agcattattt atgttggcct
     1861 cgcggactcc gtctggagtg agacacctga tgcccttaac gccgacattc ttcagactct
     1921 gacgcagcgg ataccccaat aatgaaaaaa agacatctgc ttagcttact ggcgctgggt
     1981 attagcacag cttgctacgg cgaaacatat cctgcgccca ttggtccgtc gcaatcggat
     2041 ttcggtggcg taggattatt acaaacgccc accgcgcgca tggcgcggga aggggagctg
     2101 agcctgaact atcgcgataa cgatcagtac cgttattact cagcttcagt gcaactcttc
     2161 ccgtggctgg aaacaacgct gcgctacacc gacgtgcgca cccggcagta cagcagcgtc
     2221 gaagcgttct ctggcgatca aacgtataaa gataaagcct tcgatctcaa actgcgtttg
     2281 tgggaagaga gttattggct gccgcaagtg gcggttggtg cgcgggatat cggcggtacg
     2341 gggctgtttg atgcggaata tcttgttgcc agcaaagcct gggggccgtt cgattttaca
     2401 ctcggcctgg gctggggata tctgggcacc agcggtaacg tgaaaaatcc gctctgttca
     2461 gccagtgata aatattgcta tcgcgataac agctacaaac aggcgggatc tatcgacggc
     2521 agccagatgt tccacggccc ggcctcactg tttggcggcg tggaatacca gacgccctgg
     2581 caaccgctgc gtctgaaact ggagtatgaa ggcaataatt atcagcagga ttttgccgga
     2641 aagctggagc aaaaaagtaa gtttaacgtc ggggcgattt atcgcgttac cgattgggcc
     2701 gacgttaacc ttagctatga acgtggcaac acttttatgt ttggcgtcac gctgcgcacc
     2761 aactttaacg atctgcgccc gtcttacaac gataacgccc gcccgcaata tcaaccgcag
     2821 ccgcaggatg ccattttgca gcattcggtg gtggcgaatc agttaacgct gttgaaatac
     2881 aatgccggac ttgccgatcc gcagatccag gcgaaaggcg atacgctgta tgttaccggc
     2941 gagcaggtga aatatcgtga tccgcgcgaa gggatcatcc gtgctaatcg gatcgtgatg
     3001 aacgatctgc cggatgggat aaaaacgatc cgcattacgg aaaatcgcct taatatgcca
     3061 caggtgacga cggaaaccga tgtcgccagc ctgaaaaatc atctcgccgg agagccgttg
     3121 ggccacgaaa cgaagctggc gcaaaaacgc gtcgagccag tggttccgaa gtccaccgag
     3181 cagggctggt atatcgacaa atcacgcttt gatttccata tcgatccggt gctgaaccag
     3241 tcgatcggtg gcccggaaaa cttttacatg tatcagctgg gcgtgatggg aacggcggat
     3301 ttgtggctga cggaccatct gctgaccact ggcagcctgt ttgctaacct tgccaacaac
     3361 tacgacaagt ttaactacac caatccaccg caggactcgc acttaccgcg cgtgcgtacc
     3421 catgtgcgcg agtatgtgca gaatgatgtc tatgtgaata acctgcaagc caactacttc
     3481 cagcatctgg gcaacggctt ctacggtcag gtctacggag gttatctcga aaccatgttt
     3541 ggcggcgtgg gggcagaagt gttgtatcgc ccgctggata gcaactgggc gtttggtctg
     3601 gatgccaact acgttaaaca gcgcgactgg cgtagcgcaa aagatatgat gaaattcacc
     3661 gattacagcg tgaaaaccgg acatctgacc gcgtactgga cgccatcttt cgcccaggac
     3721 gtgttagtga aagcgagcgt cgggcagtat ctggctgggg ataaaggcgg cacgctggag
     3781 atcgctaaac gctttgacag cggcgtggtg gttggcggct atgccacgat cacgaatgtt
     3841 tcgaaagagg agtacggcga aggggacttc accaaaggcg tgtatgtctc tgtaccgctg
     3901 gatctcttct cgtctggccc gacacgcagc cgtgcggcga ttggctggac gccgctgacg
     3961 cgtgacggtg gtcagcaact tgggcgtaag ttccagttgt atgacatgac cagcgaccgt
     4021 agcgtcaatt tccgctaagt catgggaaag gtgccaggtt tcgcactcac tggcaccttt
     4081 attcttaatg gcctgtcgag ccatcaggaa cgcagttcac ccccggtttg cgatctggtg
     4141 tgtaaaggcg aaaacattct gtcttcctgt ccgtcgatat cggttgcagg tctggttgcc
     4201 tgagcgactg ggccatcatt gggctggaga cattgctttg cggtaggtcg gctttatcag
     4261 cagtaccgag cggaccagca taagcaggaa gaacagagac tgataacatc aaagcagcaa
     4321 aataaggctt catttttacc acctttatca ggttacgttt catttgttcc agaggaacat
     4381 tgtcgatttt tcgcgcattg ctggtggctg ggaatcacct gaatgggtga tttttttggg
     4441 ctgtgtgttt tgccagatga gacattgatg ggagatgccc acttaattga gctgaacaaa
     4501 acatacacaa aaaatataga tctccgtcac atttttgcgt tatacaggaa gctcgccact
     4561 gtgaaggagg tactgctatg acgtcactct ctcgtccgcg cgtggagttt atctccacca
     4621 ttttgcagac cgtactcaat cttggcctgt tgtgcctcgg cctgattttg gttgtcttcc
     4681 tcggcaaaga aacggtgcat ctggctgatg tgctgttcgc gccagaacaa accagtaaat
     4741 atgagctggt agaaggtctg gtggtttact ttctctattt cgaatttatc gcgctgattg
     4801 tgaagtactt tcagtccggt tttcacttcc cgctacgtta ctttgtctat attgggatca
     4861 ctgccattgt gcgcttgatc atcgtcgatc ataaatcgcc actggatgtg ttgatctact
     4921 cggcagcgat cctgttactg gtgatcaccc tgtggttgtg taattcgaaa cggctgaagc
     4981 gggagtaaaa aaaggcgctc cgtggagcgc cgaataacag tcacaagttg ggataacgta
     5041 agttgagggt gcagcggcat aacattggca gaacaacatc tttaaccttt cacaccacct
     5101 gccgtcaggc cgttgaccag ccagcgttga gccagcaaga agacgatggt gatcggtaat
     5161 gcagacatca cggcagcggc ggcaaagtca ccccacaggt agttttgcgg gttgaggtat
     5221 tgctgcatcc ccacggccag ggtgtagctg tttacgtcac gcagtaatag cgacgcgacc
     5281 ggaacttcag taatggcagc gataaacgac aggatgaaca caaccgccag aatcggtact
     5341 gacagcggca acaggacaag gcggaaggcc tgccacggtg tcgcaccatc cagcgccgcc
     5401 gcttcttcca gcgaactgtc gatggtttcg aaataacctt tgatggtcca gacatgcagc
     5461 gcaatcccgc ccagatacgc gaaaattacg ccgccgtgag tattcaggcc aatgaatgga
     5521 atgtactcac ccagacgatc aaacaacgca tacaacgcga ccagtgaaag tactgccggg
     5581 aacatctgga aaatcagcat tcctttcagc agcgtcgctt tgcctggaaa gcgcatacgg
     5641 gcgaaagcgt aggcgcaggt ggtggagagc gccacaatgc caatcgcgga aatcccggcg
     5701 acctttaccg agttccacag ccacagcagt accgggaatg gcggtggcgt aatgcgacca
     5761 tcagcctgtt ccacgctaaa acctaacgcc agtttccagt gatcccagga gatttgctcc
     5821 gggatcagac taccggtcgc gaagttcccc tgacgcagcg agatggcgac gaccatcagc
     5881 agcgggaaca taattgccgc gataaaaagt agcagtagca ggtgagtaat aaacaaacgt
     5941 gctttttgcg atttcggttg gaccattgcc atttttgtta tctcccttaa tcaaacttca
     6001 ttcgcgtggc tttcaggttc actatcgcca gcgcgcccac cagcaggaag atcagcgtgg
     6061 caattgctgc tgccagaccg aagtcctgac ccccgccgcc ttcaaaagcg atacggtagg
     6121 tgtagttaac aagcaggtcg gtataaccgg ctggcgtggt cgtgccaaga cgatccgggc
     6181 cgccgttggt taacagttga atcagcacga agttgttaaa gttaaaggcg aagctggcga
     6241 tcatcagcgg cgtcagcggt ttaatcagca gcggcagcgt aatcttaaag aagttctgga
     6301 atggacctgc gccatccatt gctgaggctt catacaaatc gtccggaatc gctttcagca
     6361 agcccatgca gaggatcatc atgtacggat aacccagcca ggtgttgacg ataatcagca
     6421 tcgtgcgggc ggtggtcgga tcgctgaacc aggcgggctt cacgccaaac agcgcgctca
     6481 acatcatgtt gatttcacca aaactctggt taaacaaccc tttgaaaatc aagattgaaa
     6541 tgaacgatgg caccgcgtag ggcagaatca gcaggacgcg atagaccgct ttgccgcgca
     6601 acgcttccca ctgcaccaga cacgccagaa ccatgccgac cgccaccgtt aaaaagacag
     6661 tgatcagcga gaacaccacg gtccagacga aaatggcgag gaacggtttc tgaatgcctt
     6721 cgtcggtaaa gacgcgggta aagtttttcc agccggtggt cacggtgtaa ccggggctta
     6781 gcttttcatc accccagtta ccgtcggcag tgatggactg gtaaaaacca atctggtcgt
     6841 ttggacgata ttttacgcca ctctgattat tggtcagcgt gccgtcaccg tcgagtgtgt
     6901 agagcggctg cgtgccagaa aactggcgca gggagctcat catcactttg ttgccatccg
     6961 gcagaatggc ggtaatgtca ctcagtgcct gacgattctg ggtaattacg cgcagattcg
     7021 cgcgttcgcc ttcgggctgg gcggtcgttt ctttcagttg cagtttttgc tcgccgccaa
     7081 atttaaaagc gtcggagagg taatttttgc cggtttcgcc gtcgctgagc gccagttgcc
     7141 actcatcgcc cgccggataa agaccaaaat tatagatttt gcctgcttgc caggagcgat
     7201 ctagcaacac ttcctgcgca cgttcaaaag tcagctggtt agtgctgctg tagttggtga
     7261 aggcaatggc gatggtgcag accagaggga agaggacgaa taatcccatt ccagccattc
     7321 ccgggtaaac atagcgccag gcgtaggctt tacgattggc gaaaatatac agccccgctg
     7381 agctcaatat cagcgtggta atggcgaaca ggtattcccc ttgtgcgtac attaaaacaa
     7441 caaggtaacc caccagcagg ccgagcagac ctaacactga ccatttcagc gcgtcgcttt
     7501 gccaccaatg tttcttttta atgacatcca tggggttctt cctcattcca ggacggataa
     7561 ggctttcata ccttatccga caacaactgc ctgatgcgac gctgacgcgt cttatcaggc
     7621 ctacatacgt ttcaatttcg taggccggat aaggcgttca cgccgcatcc ggcatttcac
     7681 agcattactt ggtgatacga gtctgtgcat ctttcagcgc agcatccaca gtctgacgac
     7741 cgctggcggc gttgatcacc gcagtacgca cggcatacca gaaagcggac atctgcggga
     7801 tgttcggcat aatttcacct ttctgagcgt tatccatggt ggcggcaata cgtggatctt
     7861 tcgcaagttc atcctgatag gacttcagcg ctactgcacc cagcggtttg tctttattga
     7921 ccgcttccag accttcgtca gtcagcagat agttttcgag gaactctttc gccagctctt
     7981 tgttcggact ggcggcgtta atacctgcgc tcagcacgcc aacgaacggt ttagatggtt
     8041 gacctttgaa ggtcggcagt accgttacac cataattcac tttactggtg tcgatgttgg
     8101 accatgccca cgggccgttg atagtcatcg ctgtttcgcc tttattaaag gcagcttctg
     8161 cgatggagta atcggtgtct gcattcatgt gtttgttttt aatcagatca accaggaagg
     8221 tcagacccgc tttcgcgcca gcgttatcca cgcctacgtc tttaatgtcg tacttgccgt
     8281 tttcgtactt gaacgcataa cccccgtcag ccgcaattag cggccaggtg aagtatggtt
     8341 cttgcaggtt gaacatcagc gcgctcttac ctttcgcttt cagttcttta tccagcgccg
     8401 ggatctcttc ccaggttttt ggcgggttcg gcagcagatc tttgttataa atcagtgata
     8461 acgcttcgac agcgatcggg taagcaatca acttgccgtt gtaacgtacg gcatcccagg
     8521 taaacggata cagcttgtcc tggaacgctt tgtccggggt gatttcagcc aacaggccag
     8581 attgagcata gccaccaaag cggtcgtgcg cccagaagat aatgtcaggg ccatcgccag
     8641 ttgccgcaac ctgagggaat ttctcttcca gtttatccgg atgctcaacg gtgactttaa
     8701 ttccggtatc tgtctcgaat ttcttaccga cttcagcgag accgttatag cctttatcgc
     8761 cgttaatcca gattaccagt ttaccttctt cgattttggc gagagccgag gcggaaaaca
     8821 tcatcgtcgt taatgcggat aatgcgagga tgcgtgcacc tgtttttatt ttcataatct
     8881 atggtccttg ttggtgaagt gctcgtgaaa acacctaaac ggactctagt ttctttatac
     8941 ggcaacctct ttccatcctc cttgccccta cgccccatcg ttgctttgtg tgatctctgt
     9001 tacagaattg gcggtaatgt ggagatgcgc acataaaatc gccacgattt ttgcaagcaa
     9061 catcacgaaa ttccttacat gacctcggtt tagttcacag aagccgcgtt ctcatcctcc
     9121 cgcctcctcc cccataaaaa agccaggggg tggaggattt aagccatctc ctgatgacgc
     9181 atagtcagcc catcatgaat gttgctgtcg atgacaggtt gttacaaagg gagaagggca
     9241 tggcgagcgt acagctgcaa aatgtaacga aagcctgggg cgaggtcgtg gtatcgaaag
     9301 atatcaatct cgatatccat gaaggtgaat tcgtggtgtt tgtcggaccg tctggctgcg
     9361 gtaaatcgac tttactgcgc atgattgccg ggcttgagac gatcaccagc ggcgacctgt
     9421 tcatcggtga gaaacggatg aatgacactc cgcctgcaga acgcggcgtt ggtatggtgt
     9481 ttcagtctta cgcgctctat ccccacctgt cagtagcaga aaacatgtca tttggcctga
     9541 aactggctgg cgcgaaaaaa gaagtgatta accagcgagt taaccaggtt gcggaagtgc
     9601 tgcaactggc gcatttgctg gatcgcaaac cgaaagcgct ctccggtggt cagcgtcagc
     9661 gtgtggcgat tggccgtacg ctggtggccg agccaagcgt atttttgctc gatgaaccgc
     9721 tctccaacct cgatgctgca ctgcgtgtgc aaatgcgtat cgaaatctcc cgtctgcata
     9781 aacgcctggg ccgcacaatg atttacgtca cccacgatca ggtcgaagcg atgacgctgg
     9841 ccgacaaaat cgtggtgctg gacgctggtc gcgtggcgca ggttgggaaa ccgctggagc
     9901 tgtatcacta tccggcagac cgttttgtcg ccggatttat cggttcgcca aagatgaact
     9961 tcctgccagt aaaagtgacc gccaccgcaa tcgatcaagt gcaggtggag ctgccgatgc
    10021 cgaatcgtca gcaagtctgg ctaccggtcg aaagccgtga tgtccaggtg ggagccaata
    10081 tgtcgctggg tattcgcccg gagcatctac tgccgagtga tatcgctgac gtcatccttg
    10141 agggtgaagt tcaggtcgtc gagcaactcg gcaacgaaac gcaaatccat atccagatcc
    10201 cttccattcg tcaaaacctg gtgtaccgcc agaacgacgt ggtgttggta gaagaaggtg
    10261 ccacattcgc tatcggcctg ccgccagagc gttgccatct gttccgtgag gatggcactg
    10321 catgtcgtcg actgcataag gagccgggcg tttaagcacc ccacaaaaca cacaaagcct
    10381 gtcacaggtg atgtgaaaaa agaaaagcaa tgactcagga gatagaatga tgattactct
    10441 gcgcaaactt cctctggcgg ttgccgtcgc agcgggcgta atgtctgctc aggcaatggc
    10501 tgttgatttc cacggctatg cacgttccgg tattggctgg acaggtagcg gcggcgaaca
    10561 acagtgtttc cagactaccg gtgctcaaag taaataccgt cttggcaacg aatgtgaaac
    10621 ttatgctgaa ttaaaattgg gtcaggaagt gtggaaagag ggcgataaga gcttctattt
    10681 cgacactaac gtggcctatt ccgtcgcgca acagaatgac tgggaagcta ccgatccggc
    10741 tttccgtgaa gcaaacgtgc agggtaaaaa cctgatcgaa tggctgccag gctccaccat
    10801 ctgggcaggt aagcgcttct accaacgtca tgacgttcat atgatcgact tctactactg
    10861 ggatatttct ggtcctggtg ccggtctgga aaacatcgat gttggcttcg gtaaactctc
    10921 tctggcagca acccgctcct ctgaagcggg gggttcttcc tctttcgcca gcaacaatat
    10981 ttatgactat accaacgaaa ccgcgaacga cgttttcgat gtgcgtttag cgcagatgga
    11041 aatcaacccg ggcggcacat tagaactggg tgtcgactac ggtcgtgcca acctgcgtga
    11101 taactatcgt ctggttgatg gcgcatcgaa agacggctgg ttattcactg ctgaacatac
    11161 tcagagtgtc ctgaagggct ttaacaagtt tgttgttcag tacgctactg actcgatgac
    11221 ctcgcagggt aaaggtctgt cgcagggttc tggcgtcgcg tttgataacg aaaaatttgc
    11281 ctacaatatc aataacaacg gtcacatgct gcgtatcctc gaccacggtg cgatctccat
    11341 gggcgacaac tgggacatga tgtacgtggg tatgtaccag gatatcaact gggataacga
    11401 caacggcacc aagtggtgga ccgtcggtat tcgcccgatg tacaagtgga cgccaatcat
    11461 gagcaccgtg atggaaatcg gctacgacaa cgtcgaatcc cagcgcaccg gcgacaagaa
    11521 caatcagtac aaaattaccc tcgcacaaca atggcaggct ggcgacagca tctggtcacg
    11581 cccggctatt cgtgtcttcg caacctacgc caagtgggat gagaaatggg gttatgacta
    11641 caccggtagc tcttcaacca acccatacta cggcaaggct gtgtcggctg atttcaatgg
    11701 cggtagcttc ggtcgtggcg acagcgacga gtggaccttc ggtgctcaga tggaaatctg
    11761 gtggtaatag caaaaaactg ggccggataa ggtgtttgca ccgcatccgg caatcaatgc
    11821 ctgatgcgac gctgttgcgt cttatcaggc ctacaaccgc tgccgaaagt aggccggata
    11881 aggcgtttac gccgcatccg gcataaaaac agctttaagg ggcgaaagcc cctctgatta
    11941 tcgggtttag cgcgctattg cctggctacc gctgagctcc agattttgag gtgaaaacaa
    12001 tgaaaatgaa taaaagtctc atcgctctct gtttatcagc agggttgctg gcaagcgcac
    12061 ctggaatcag ccttgccgat gttaactacg taccgcaaaa caccagcgac gcgccagcca
    12121 ttccatctgc cgcgctgcaa caactcacct ggacaccggt cgatcaatct aaaacccaga
    12181 cgactcaact gtcgaccggc ggccaacaac tgaacgtttc cggcatcagt ggtccggttg
    12241 ctgcgtacag cgtcccggca aacattggtg aactgacact gacgctgacc agcgaagtga
    12301 acaaacaaac cagcgtattt gcgccgaacg tgctgattct tgatcagaac atgaccccat
    12361 cagccttctt ccccagcagt tatttcacct accaggaacc cggcgtgatg agtgcagatc
    12421 gtctggaagg cgttatgcgc ctgacaccgg cactggggca acagaaactc tatgtactgg
    12481 tcttcaccac ggaaaaagat ctccagcaga caacccaact gctcgacccg gcaaaagcct
    12541 atgccaaagg cgtaggtaac tcggtgccgg atattcctga cccgattgcc cgtcacacca
    12601 ctgatggttt gctgaaactg aaagtgaaaa cgaactccag ctccagcgtg ttggtaggac
    12661 cactatttgg ttcttccgct ccagctccgg ttacggtagg taacacggcg gcaccagctg
    12721 tggctgcacc cgctccggca ccggtgaaga aaagcgagcc gatgctcaac gacacggaaa
    12781 gttattttaa taccgcgatc aaaaacgctg tcgcgaaagg tgatgttgat aaggcgttaa
    12841 aactgcttga tgaagctgaa cgcctggggt cgacatctgc ccgttccacc tttatcagca
    12901 gtgtaaaagg caaggggtaa ttacgctcca cagtgctgat tttgcaacaa ctggtgcgtc
    12961 tcctggcgca cctttttttc tcctcctgta ctattgttgc gtttttgttg cgcattagtt
    13021 cacttaattt gctttacatc tcccgtaaat atttttctgc gatacaatgc ctttacgtta
    13081 tgtaacggag agttcggcat gtcacacccc gcgttaacgc aactgcgtgc gctgcgctat
    13141 tttacagaga tccctgccct ggagccgcaa ctgctcgact ggctgttgct ggaagattcc
    13201 atgacaaaac gttttgaaca gcagggaaaa acggtgagcg tgacgatgat ccgcgaaggg
    13261 tttgtcgagc agaatgaaat ccccgaagaa ctgccactgc tgccgaaaga gtctcgttac
    13321 tggttacgtg aaattttgtt atgtgccgat ggtgaaccgt ggcttgccgg tcgtaccgtc
    13381 gttcctgtgt caacgttaag cgggccggag ctggcgttac aaaaattagg taaaacgccg
    13441 ttaggacgct atctgttcac atcatcgaca ttaacccggg actttattga gataggccgt
    13501 gatgccggac tgtgggggcg acgttcccgc ctgcgattaa gcggtaaacc gctgttgcta
    13561 acagaactgt ttttaccggc gtcaccgttg tactaagagg aaaaaaatat ggagtggagt
    13621 ctgacgcaga ataagctgct ggcgtttcat cgcttaatgc gtacggataa gccaattggc
    13681 gcgttactgc tgctctggcc aacattatgg gcgttgtggg tggcgacacc gggcgttccc
    13741 cagctctgga tcctggcggt gtttgtcgcg ggcgtctggc tgatgcgcgc tgctggttgc
    13801 gtggtgaatg attatgctga ccgcaagttt gatggtcatg ttaagcgcac ggcgaaccga
    13861 ccacttccca gcggcgcggt gacagagaaa gaagcgcgta cgctgtttgt agtgctggta
    13921 ctgatttcat ttttactggt gctgacgctg aatacgatga ctattctgtt gtcaattgcc
    13981 gcgctggcgc tggcgtgggt atacccgttt atgaagcggt atacccatct accgcaagtg
    14041 gtgctgggcg cggcgtttgg ctggtcgatt ccaatggctt ttgccgctgt gagtgagtcg
    14101 gtgccattga gttgctggtt aatgttcctc gccaatattc tctgggcggt ggcttacgac
    14161 acgcagtatg cgatggttga ccgcgatgat gatgtgaaga ttggcattaa atccaccgca
    14221 atcctgttcg gccaatacga taaattgatt attggtattt tgcagattgg cgtactagcg
    14281 ctgatggcga tcatcggtga gttaaatggc ttaggctggg gatattactg gtcaattctg
    14341 gtagctggcg cgctgtttgt ttatcaacaa aaactgattg ccaaccgcga gcgtgaagcc
    14401 tgctttaaag catttatgaa taataactat gttggtctgg tactgttttt agggctggca
    14461 atgagttact ggcatttctg atgatgtaaa aaagccggat gatcatccgg ctttcttctg
    14521 ggttgcctga tgcgctgcgc ttctcaggcc tacacaacat atcgcaattt attgaatttg
    14581 cagatcatgg taggccgaat aaggcgtttg cgtcgcatcc ggcaattctc actgattacc
    14641 cttcgccctg cgtcgcactc tcaatcgtca aacgcacgtc tgatgtaatc aactccgcca
    14701 gcaactgata taccttcatc gtttctgccg gttcggcgtc gccgctatcg ctgatatacc
    14761 cttcatcacg cagcgtcagc accagagaac tgaacaccgc cttgtcgaag aattccggcg
    14821 cgttgatacc gtgcagcacg gagagacgtt gcgcgacggt gcggctctct ttttccagcg
    14881 taccgcggtt gatcgacggg ttggcactca acagccagaa ggtgatggca taacgttgca
    14941 gcgtttcgcg cgcgcctgcg gccagcagct gtagcgtgcg agaatgcgcc gggttgatat
    15001 gcaactcatc atcttgcagg gtaatcagcc cctgacgttg catctcattt gccagcgcat
    15061 caataacgtc cggtaactcg tcgcgatccc agcgcaggaa cagttccgct ttcagcattg
    15121 ggtaaagcac attgacgtgc tccatcaata cgtcgcggga gatgtggcga tgctgggtga
    15181 caattgccgc catcagcgaa ggcagcacca acatatgcgc aatgttgttg cgatagtagg
    15241 tcatcagcac cgcttgctcg cgcggcagaa tgatgatgtc gccgatagtg tctttctcga
    15301 cttcaaactt gttcatttgc agcgcgtgat cgataagctc gctggcgctg gctgaaggaa
    15361 cggtagagtc cgtggagtaa ggcacgttgc gcatcagatc caggtagcag ttgagttgct
    15421 tggttaactg ctcgcgggtg agtgagcgct gacgtgacgc cagaagcgca gtacagcaca
    15481 ggttcatggc gttcgccgcg cctgcgttgt taatgcgtac catcagatcg gcagcaatat
    15541 tattgaccgt cggcgttaac caggccggac gcaccgcttc gatgggatcg atagattcac
    15601 gccagtctgg tacgtgctgg ttaaggtagg tcatcaacgg cattggttca ccgaagttga
    15661 cgtaaccctg accgagatta cgcagcttgc ttaaaccgcg cagcatctgc ggcaggctct
    15721 ctttctcttt cgtcgcaccg cgcagttctt tggcgtaagt acccacttcc atgacgtgct
    15781 cataaccgat atagatcgga atcagcgtaa tcggacgagt gccgccacgc agcatcgcct
    15841 gaatggtcat cgatagcgta ccggttttcg gatccagcaa acgccccgta cgggaacgac
    15901 cgccttccac gaaatactcg acggaataac cacggctgaa cagttcgccg agatactcac
    15961 ggaaaacggt ggaataaagt ttattgcctt taaacgtacg gcgaataaag aacgccccca
    16021 gacggcggaa aatcggcccg gccggccaga agttcaggtt gatcccggcg gcgatatgcg
    16081 gcggcaccag cccctggtga tacagcacgt aagaaagcag caggtagtcc atgtgactgc
    16141 ggtggcaagg cacatacact agctcatggc cgtcgtgggc cagctggcga acgcgctcgg
    16201 cgttatggac gttgataccc tggtaaagtc ggttccaggt gaagcccaga atgcggtcag
    16261 tcaggcggat catctcgtaa gagaaattcg ccgcaatctc ttccatcagc gcaatcgcgt
    16321 tctgctgcgc tttttcatgg gagatttttt tgctgcgtgc ttcatcttct accgctttcg
    16381 caatggcgcg ggaggcgagc agcttattaa acagatcctg acgagcaggc agacgtggac
    16441 ccacggcagc cagacgttga cgggcaaagt gcatacgcgc cacgcgcgcc agtttctgag
    16501 cgatagtttt atccgtgccg tgttcatccg ccatacggcg cagtgaaact gacggcgaga
    16561 aacgcacaaa actgtcgcga ccgagccaca gtacagcgaa aaatttctgt acgccgttaa
    16621 gcatacgcag cggcgggttc acttcgcctt tttcacgccc cggcgcgcga ccaaacatca
    16681 ccgatactgg caccatctgc acatccagat ttgggttgct gcggtgcaaa tcgagatagt
    16741 cgtggaacag cttaatagac tcttctttcg gcgtgtaata ggtgaacaca cgcggcccgc
    16801 cgtgaatgaa cacatagcgc ggcagtagcg tgccgtcgat ttccagcggt tctaacgggt
    16861 caggcaggtc atgtgccaga cactgggcgc gcaacgtcag caagtcagct ttcgagttgt
    16921 acggtaaaac gtacataatt ggacgagagg tatccagccc cagttccggg gcaggatccg
    16981 ccggaataga cttgcttttt accaggatgc ttaatggtaa attcagtaat ttgtagtaaa
    17041 ttcgtggcca gccggacata aacgatgtaa agcctctggt taataatgca aatgcgcggc
    17101 aaggatagca gaaagtcatg ggaaattctg tggtatccgc tcatgtttcg cgcggcgtta
    17161 cgcaaacccg aatcatcgga tttaacggta cactgatatt gacgctcata atgtaaaaag
    17221 gttctttcaa tggccaataa taccactgga ttcatccgaa ttattaaagc tgctggctat
    17281 tcctggaaag gtttacgcgc tgcatggatc aacgaagcgg cattccgtca ggaaggcgta
    17341 gcggtattgt tagcggtggt tatcgcctgc tggctggatg tggacgcgat tacccgcgtg
    17401 ctgcttatca gctccgtgat gctggtgatg attgtggaaa ttctcaatag cgccatcgaa
    17461 gctgtggttg accgaattgg ctctgaatac catgagcttt ccggacgcgc taaagatatg
    17521 ggatctgccg cagtgctgat tgccattatc gtcgccgtga ttacctggtg catcctgtta
    17581 tggtcgcatt ttggataacc cttccagatt tcgataaatc tctggtttat tgtgcagttt
    17641 atggttccaa aatcgccttt tgctgtatat actcacagca taactgtata tacacccagg
    17701 gggcggaatg aaagcgttaa cggccaggca acaagaggtg tttgatctca tccgtgatca
    17761 catcagccag acaggtatgc cgccgacgcg tgcggaaatc gcgcagcgtt tggggttccg
    17821 ttccccaaac gcggctgaag aacatctgaa ggcgctggca cgcaaaggcg ttattgaaat
    17881 tgtttccggc gcatcacgcg ggattcgttt attgcaggaa gaggaagaag ggttgccgct
    17941 ggtaggtcgt gtggctgccg gtgaaccgct tctggcgcaa cagcatattg aaggtcatta
    18001 tcaggtcgat ccttccttgt tcaagccgaa tgctgatttc ctgctgcgtg tcagcgggat
    18061 gtcgatgaaa gatatcggca ttatggatgg cgatttgctg gcagtgcata aaactcagga
    18121 tgtacgtaac ggtcaggtcg ttgtcgcacg tattgatgac gaagttaccg ttaaacgcct
    18181 gaaaaaacag ggcaataaag tcgaactgtt gccagaaaac agcgagttta aaccaattgt
    18241 cgttgacctt cgtcagcaga gcttcaccat tgaggggctg gcggttgggg ttattcgcaa
    18301 cggcgactgg ctgtaacata tctctgagac cgcgatgccg cctggcgtcg cggtttgttt
    18361 ttcatctctc ttcatcaggc ttgtctgcat ggcattcctc acttcatctg ataaagcact
    18421 ctggcatctc gccttaccca tgattttctc caatatcacc gttccgttgc tgggactggt
    18481 cgatacggcg gtaattggtc atcttgatag tccggtttat ttaggcggcg tggcggttgg
    18541 tgcaacggcg accagctttc tctttatgtt gttgctgttt ttacgcatga gcaccaccgg
    18601 gctgactgca caggcttatg gtgccaaaaa tcctcaggca ttagcccgtg cgctggtgca
    18661 accgttgctg ttggcgttgg gggccggggc gttaattgcg ctgctgcgta cgccgattat
    18721 cgatctggcg ctgcatattg ttggtggtag tgaagcagtc ctggaacagg cgcgacgctt
    18781 tcttgaaatc cgctggttaa gcgcaccggc gtcgctggcg aatctggtat tacttggctg
    18841 gttactcggc gtgcaatatg cccgtgcgcc agtaattttg ttagtggtcg gcaatatcct
    18901 caacattgtg ctggatgtct ggctggtgat ggggctgcat atgaacgtgc agggcgcggc
    18961 tctggcgacg gttattgcgg aatatgcaac attgctgatt ggtctgctaa tggtgcgtaa
    19021 aattctcaaa ctacgcggaa tctccggcga aatgctgaaa acagcctggc gaggaaactt
    19081 ccgtcacttg ctggcgctta accgcgatat catgctgcgc tcgctgttgc tgcaactctg
    19141 tttcggcgcg atcactgtac ttggcgcgcg actggggagt gacattatcg ctgttaacgc
    19201 ggttctgatg acgctactca cctttaccgc ctatgcgctg gatggttttg cctacgcggt
    19261 tgaagcacat tccggtcagg catacggtgc gcgcgacggt agtcaattgc tggatgtctg
    19321 gcgggcagcg tgccgccagt cggggatcgt agcgttactg ttttcggtgg tttatttgct
    19381 ggcaggggaa cacatcattg cgttgctgac gtcgttaacc cagattcagc agctggctga
    19441 ccgctatctt atctggcagg tgattttgcc gttggtcggc gtctggtgtt atctgctgga
    19501 cggcatgttt ataggcgcaa cgcgtgccgc cgaaatgcgt aacagtatgg cggtggccgc
    19561 cgcaggtttt gcactgacgc tccttacgct gccgtggctg gggaatcatg gtttgtggct
    19621 ggcgttaacc gtctttctgg cgttacgcgg gctttctctg gcggctatct ggcggcgtca
    19681 ctggcgtaac gatacctggt ttgtcgcaac gtgacggtta aaaattctga ataaataatc
    19741 ctaagccaaa ttgctgacta cacttaatct cacgttcaga agaaaagtga acgtactctc
    19801 attcacaacc taacgatgag gtcttgatta tgaataaaga tgaagccggc ggtaactgga
    19861 aacagtttaa aggtaaagtg aaagagcaat ggggcaaact gaccgatgat gatatgacga
    19921 tcattgaagg aaaacgtgat cagttagtgg gtaaaatcca ggaacgctac ggttatcaga
    19981 aagatcaggc agaaaaagag gttgatagtt gggaaaaacg ccatgattac cgctggtaat
    20041 taatccctcc tgcccgacat gtacaaggat gtacaccctt ttagcgaggt ttctttttca
    20101 cctgaataga gtggtcatga tggcactgtt caggatgacg acacgcttct acttctacac
    20161 atgctgaaca taatccatgt gcttcaataa cattatgccg cagggcaaaa cccatttttg
    20221 ccgccagcgt atgcatgatg tcttccacgc cttcagcaca ttcttctttc accgcgccgc
    20281 agcgatcgca aataaacatg gctgaagtat gggtgggctg atcgaacaga tgacagagca
    20341 cataactgtt ggtggattcc accttatgca caaaaccttg ttcaagcaga aactccagcg
    20401 cgcgataaac cgttggcggc ttggcttgcg gttcagcttc gcgcagcaaa tcaagcagat
    20461 cataagcgct gatagcgcca tcctgcagac tcatcaggcg caacacttcg agacgctgtg
    20521 gggtcaggcg cacattacgc tgtgcgcaga ttttttcagc ctgcgctaat aactcctgcg
    20581 ttgtggtctt ttccattggg cacctcgaca gtggggttaa gaatgtcctt actttaccat
    20641 agttctcact taaacgccga gaacagggtg tcatggctgt cacattgcct gatcgcatat
    20701 tcgttatgct atagtagcgc ccccaattta ccagatgctt aaaaagtcgc catgccagca
    20761 gaatcacaca ctgtttatcc cgcttaccgt ttctcgattg ccccgatgct tgactggacg
    20821 gacagacatt gccgttattt cctgcgtctg ctttcccgca atacgttgct gtataccgaa
    20881 atggtgacca caggggcgat tattcacggt aaaggtgatt acctggcgta cagtgaagaa
    20941 gaacatccgg tagcgttgca actcgggggt agcgatccgg cggcgctggc acagtgtgcg
    21001 aagctggcag aagcgcgcgg atatgatgag atcaacctga atgtcggctg cccgtctgac
    21061 cgggtgcaga acggcatgtt tggtgcgtgt ctgatgggta atgcgcagct ggttgccgac
    21121 tgcgtgaaag cgatgcgcga tgtggtgtcg attccggtga cggtgaaaac gcgtattggc
    21181 atcgatgatc aggacagcta tgaatttctc tgcgatttca tcaacaccgt ttccggcaaa
    21241 ggtgagtgtg agatgttcat catccacgca cgtaaagcct ggctttctgg gttaagtccg
    21301 aaagaaaacc gtgagatccc gccgctcgat tatccgcgtg tgtatcaact gaagcgtgac
    21361 tttccgcatc tgacgatgtc gattaacggt ggtatcaagt cgctggaaga agctaaagcg
    21421 catttgcaac atatggatgg cgtgatggtc gggcgcgagg cgtatcagaa tccggggatt
    21481 ctggcggcgg tagaccgaga gatttttggt tcctcggata ccgatgccga tccggtggcg
    21541 gtagtgcgcg ccatgtatcc gtacattgag cgtgaactca gccaggggac gtatctcggc
    21601 catattaccc ggcatatgct gggcttgttc cagggtattc ctggcgcgcg gcagtggcga
    21661 cgttatttaa gtgaaaatgc ccataaagcg ggtgcagaca ttaatgtgct ggaacacgcg
    21721 ctcaaactgg tggcggataa gcgttaactt ttcaccaaaa agtagtcaaa ttcaccacgc
    21781 cctgcgcacc gtcgcggggc gttttgctgt taaatcaata gattattttt ggcatgattc
    21841 ttgtaatgcc agcaagagat ttcatatttg ggagagcatc atgctggaac tactttttgt
    21901 aattggcttt tttgtcatgc tgatggtcac tggtgtttcg ttgctgggta ttatcgccgc
    21961 gctgattgtg gcgacggcct ttatgttcct cggcggtatg ctggcattga tgattaagtt
    22021 gctgccgtgg ctgctgttgg cggttgcggt ggtgtgggtg atcagggcga ttaaagcacc
    22081 aaaagtgccg aaatatcagc attatgaccg ctggcgttac taagggattg tgcggatgat
    22141 cacaacctaa ggttttatcc ttagaacaaa ataggaattg ataatcaaat ctgtcactat
    22201 tgcgtgtcaa acaaattcat cgagctgtac cctacataca gccgaactat aaaagaaagg
    22261 gcttcccagg tggaagccca atttctttta tggaatcaac aggctggaac cctgcgtcgc
    22321 ccggctttcc agaatctcat gcgcacgccg cgcatccttc agcggatatt tctgctgctc
    22381 ggcgacatcg accttaatca caccgctggc aatcaaagag aacagttcat tactggcctc
    22441 ggttaattcc tcccgcgtgg tgatatagcc ttgcagggaa gggcgtgtca catacaacga
    22501 gcctttctga ttgagaatgc ctaagttcac accggtaacc gcacctgatg agttgccaaa
    22561 actcaccatt aagccgcggc gttgcaggca atccagcgac cgttcccagg tgtctctgcc
    22621 cactgaatcg tacaccacgc gcactttctt gccaccggtg atctctttta accgctcgac
    22681 cagattctct tcacgatagt taataacctg ccatgcgccc gcttttagcg cactctgcgc
    22741 tttttgcgcg gttcccacgg tgccgataag tttcgcgccc agggcttttg cccactggca
    22801 ggcaatcaag ccaacgccgc cagccgctgc gtggaacagg aactgttcat cgggtttaat
    22861 ttcataggtt ttgcgcagca gataataaac cgttaagcct ttcaggaagg atgccgcagc
    22921 ttgctcaaaa gaaattgccg caggcagaat cgccgcttta tccgcattaa tgttatgcat
    22981 agagctgtaa gcgcctaatg ccgattgtgc atagactacg cgatcgcctg ccttaatatg
    23041 ctttacacca ctgccgactt tactcacgat gcctgccgct tcggtgccta atccgctggg
    23101 tagcgatggt ggcgggtaaa ggccgctgcg gatatacgtg tcgataaaat tgatgccgat
    23161 ggctttattt ttgacctgga tttcattctc cgccggatcg gcaggagtga actccacggc
    23221 ctgaagtact tccgggccac cgtgcttgtg aaattcgatg cgcgttgcca tttaaactcc
    23281 tttactgagc gacatatctg ttttaagcct aacagtagtc gccaggccgc gcggggattt
    23341 tttccgggct gcggtcacaa cccggaatat ctctgatcag tattgaaacg gcgtcgccgc
    23401 aatccagttt tgccactggc gctcaaagtt ggttagcgtt aatacgcccc gttcacggca
    23461 cgggcgagtc caggtttggt aatcattagc ttcccgacaa acacaaatca tatattgcct
    23521 ggcatcctga ttttctggcc gaaaacgcca ggccaggagt ggcccacctg gtgtttgcgg
    23581 tgcaataccg gcttcgccat catagatagc cctggcacca cgactcccac caccgttttc
    23641 gacataacat tgtaaagaac gcagtacagc cagcgccagt tgcgcacttt gccgccactg
    23701 gaaagattgt gccaggctgt tttcatcgca ttgaatacct tcccggcgaa tatcttcaca
    23761 aagtgttgcc agggtttgcg cggcagtgtt gatcccctgt gtatgacaca aaattgcggc
    23821 atggtggctc atggtatttt gtatcgtttc tcgcacgtcg tcacgtagca gcccctgatt
    23881 caggtactgt tgcgcctcat taatcgtact gagaatttgt tgcctctcga gaggccggtc
    23941 ctggcttttc tgatgagcaa tatgtaatgc acagcggcgg gcgaaaactt gcccggcatt
    24001 gagcgctgct ccacctgggc gcgtgacacc atgtgttccg gcattttctc cggcagcata
    24061 acaaccagtt agcgatgtac gtccccaaat atcaacttca attccgccat taagatgttg
    24121 attatttagc gtaaacttga gcggtgaggc tgtgagatca tgaccgtgca tctgatacaa
    24181 acgaatagcc agaggattca tctgtgttaa tctcgccagc ggttgtgcca acagggcgtg
    24241 attttgttgc agatagtcga tgacatcatc atccagttct tgcaggttga atgacgttcc
    24301 gtccgctgcg ggttctggtt cccgtagaaa atcaagaaaa acatcgcgcc ctttttgagt
    24361 ctcttcataa actgcgacat ccagcaggct ggagccatat tccagcattc gttccgcgtg
    24421 aaacggccac tggtaacctt tacgaaatat tgcggaggcc agcatacgag tcgtggggta
    24481 ataagctgcc agaaaattat actgacgccc ggagtggtcc tgcgaataga tgcgcggcat
    24541 cgcctgcatg taagtaccgg aaagattcca cggaaactgg ctgcgcggtg taccgatacc
    24601 aaactgactt tccgtaagat taaccagagt tatacctgct tccagtgcca tgcccaacgc
    24661 actaaaacag ttcaccggat aaacactgtc acgataaagt tcacctggtc cgcccgtggc
    24721 taaaaccaga tgctggcagc gaatcacgac cattcgccag ggattatccc gacaggcttt
    24781 atcgatggcg atcaccccca cgactcgtcg attttcccct tcaccactgg tcaggatatg
    24841 aatcgccgtt gtgtgatcgc aaagaggaat attaaggcgc attgcctcct gggccagcac
    24901 cttcaccatc aggcgcgatg ttcgaggacc gcagctagtg gcacggccaa attcatcgtg
    24961 atcggtttga taacgcaacg ttgcgccaaa gagatcttca ggcagatcca gacccagata
    25021 tttcagtact tcacaggtgt tcaccgatcc gaccgcctca acatatgcgg tgtcatgatc
    25081 catcgcacca cctgccgcca gggtgttact taatgtcaga aaatggtcac catttgcacg
    25141 cgtattcgcg gtgtgaagcg tttgtttatc ggaaccagaa caggcggaag tgccccagaa
    25201 ggctttgctg gaggcgacca ttacatcgac attttgccgt ttcagctcga cggcagctcg
    25261 ccatcctgcc gcgccactgc ccagaaccag cgtgttgcag cagtactctg gtaaaatggt
    25321 accgttaagg tcgatactac cgctggcttg agccagcggt gcgtaatggg gcattttgat
    25381 atcagtgagc gccgttagcg tttcgtcaat cattgcgtcc cacctatttc atcagacttt
    25441 cgattaagcc gctcattgcc atatagccca tgattagcgt aaatacgctt atggcaataa
    25501 acatgacgtt ttcccagcgt gagcaacgat atttgcccat taacgaaggc ttgttcgcca
    25561 gccagaacat acataaaaca gtcagcggca gaataatggc gttaaaggcc tggctggcaa
    25621 tcatcaccaa taccgggcgt gcgtggaaca gcggcacaac cagacaaagc agagacataa
    25681 ccgtcatcag gatacggtaa cctgggctaa cttcgttgct ggtatcacgc cagtcagcca
    25741 gcagccaggg cgttaacagc aaatttggga actggctgga aagcccggct gcaacaatac
    25801 caataacaaa gagccccacg gcagctgagc cagcaatagg ttcgagaata atgaccattt
    25861 gcgaggcatt atttaaacct gtgccagttt ggtacaacgt acccgcagcc gcagccatca
    25921 ccgccgcact gatgatgaac atcattcctg cactgacaat ggcatcacga ttttgatgag
    25981 gcaaattgtc cacaccccaa ccattacttt ttaccagggt cgtgcgcata agaaacattg
    26041 ctggtgctac ggtggtaccc accatgccag aaattatcag aaatggcgta ctgttatcgc
    26101 cagcgacagg atcgggaaca gacggaataa atccggccag cagatctgcg accggcggca
    26161 tcataatgaa aaaattaatc acaaacgcca gccccataat gccaaccagc gcggagagga
    26221 ttttgtcgaa cccggcgttg ctgttggtcc agagcatcac gttaatcata atgaccatcg
    26281 cgatagccca ggcgagagct gagataccgc cactaaacca ggtcgtggac catgttgcca
    26341 ttacatccgc cagaataccc attaccccca taatggaacc gctcacggca acggttaacc
    26401 cgatcagaaa caacatcgca acgccgggat ggatatggcg acgaaatgca gtcaacgcgc
    26461 gttcaccagt gacggaagca taacgaccat aaatacggat taaaaaccag gtaacaatgc
    26521 aagaaagcgc cacggcccac atgagcgaga caccatagtt agcacctgct ttagccatag
    26581 tggtgatgct gcctgttccg atgctgtagc caataagaaa gatgccaggt gcaaaggccg
    26641 cgagttttgt cattattcgc cgaaataaag aaggcgtttg gggaacagag gttgtcatat
    26701 tcattatctt tctttccttg taagaggcga tcagcgtgcc tgaaagtgcg gttgacgctt
    26761 ctcagtaaat gcctgactgc cttcatgagc atcttcagtc gtggcggaaa aagcgccagc
    26821 cagtgcttca agcgtcgagg ccacagcaat accttctccg gcatcaataa cctgcttggc
    26881 gatctgcact gcaacgggag cacgctgggc gatacgttgt gccagttgca gtccggcgtc
    26941 gtgtaacgcc tccctggcga caacgcgatt caccagcccg caggacagtg cccgctgtgc
    27001 atccagtggt tcaccggtaa ataccagttc tttcaccagt gagcgcccaa gcagtgccgt
    27061 cagccgctgc gttcctgacc agccaggcac tgtcgccagc ccggtttctg gtagtgccat
    27121 ttgtgcttcg gcgctacaaa tacggatatc ggcggtagca gccagttcca gaccaccgcc
    27181 ataagccagg ccgtgcaaca gggcgattac gggctgtggc agttgtgcca gagcatcaaa
    27241 tgcctgatga ccgcggcgga tccagttgcg ccacatatcg agtgcagaaa gagaggtcca
    27301 gcgatgaata tccgcgccga cacaaaacgc tttttcactg gcactggtca gcagtactac
    27361 gcggatctcc gaatcagttt ccaacgtgtg gcaatgcgcc agcagttgtt cgagcatctc
    27421 tggggttaat gcgttgagtt tcgccgggcg attaatcacc aaagtggcaa tgaaaccgtt
    27481 gcgctggagg tcaatggtgc cgttattcat ggtgacttcc ttgttgaaaa tagaggggat
    27541 tcattagttt gagatcgtct gccagacgga gtggggcatc gctttgggcg agaatgtcgc
    27601 gttcaggatc aatacctggg gcaatttctg tgaccagtag cccgtctggg gttaattcca
    27661 gaacgcagcg ttcagtaatg tactgtactt gttgcccgag tcttattgcg cgtttgccgg
    27721 agaacgtcac gtgggcgacg tcctgtacca gttttttggc tttgccttct ttaatgatac
    27781 gcagctgacc ctcttccagt tgcagttggg caccggcatt gaaaaagcca gagaaaataa
    27841 tgcgtttcgc atgtgaggtg atatcaataa atccaccgca tccggcagtg acatgtggac
    27901 gagcggggag atgtgagacg ttcactgagc catctgcgcc gatttgtaaa aacgacatca
    27961 gagtgagatc aaaaccacca ccctggaaat aggtgaactg ctggggagag ggcaaaaatg
    28021 cttctgcatt agaggcacaa ccgaactgaa attccagcag tggaactccg ccaatcgcgc
    28081 cctgttccag cagccaggtg acgtcaccgt ggcgaccttg ttccagtaaa atgcgtggta
    28141 cgttggcaga aataccaaag ccaatattta ccgcatctcc actttgtagt tcttgcgcga
    28201 ctcgctgggc aataactcgc gccgggccat gttccatata acgaaaggct gacagcggac
    28261 gactgatttc gccggaaatg gcaggttcat attgcgtttg tgtcgtttgt gtttgttccg
    28321 gcgcaatcac gatgtaatcc accagtacac ccggaatacg cacctctttt ggtttcagac
    28381 ttccggcggc aacctgtcgt tttacttgcg caattatgat gccaccatta ttgcgaacgg
    28441 cagtagcctg ttccagtggc cccagataag ccccttcatg ttcataagtc aggttgccgc
    28501 gttcatcggc agtggtagcg cgaatgatcg ccacctgcgg cacgatactg gggaaaaaca
    28561 gccagtcgtc gttagcaaat cgaacacgtt caaccagaga ttgttgcgcc gctttttcat
    28621 tcattgcacc gccctgcaac aggggatcca cataggtatc catgcctgtt tgtgtcagca
    28681 cgccaggacg atgagccgcc gcttcccggt gcatatcaaa taagatcccg gaaggcagat
    28741 tccaggcggg gatcgcgttg tcattgatca tttgccagat taacggaggc gtcattgatg
    28801 atggaccgga ggggtaggag ccagcgatca cttttgccag taagcccggt tgcgccagat
    28861 gatcgatgcc ttttacgcca tacatatcac cagcggcgat agggtggatg gaggtgatgt
    28921 tttgcggatg tccggcacgt tgaaagcgtt cacctattgc tgccagcacc gcatccggac
    28981 accccattcc actggaggag gagacggtga caactgcgcc atcaacaatc aaatctgcag
    29041 cttccggtgc agtgatcgtg cgtacagagc acataataat ttccttgttt cgatataaaa
    29101 ataattaaaa atatacattt aaaacaatat gataattttc ataaattaat tggaacgatc
    29161 taatttatgc gtaatttgta cgattagggt gtaaaaaaca caacaaggga agtgcgaatc
    29221 tgtgatcgaa acgacgatct cctgcgatcc cttgcgttaa cggatcgcat gagtaaaagg
    29281 agattatgat aaagtaattg ccttgatctt atgggggttt ggagcaggca tggcgaagtc
    29341 ggatacagga agaaagcggg taacattaac cgatgttgcg cgtgcggctg gcgtttcgaa
    29401 atcgactgta tcgctggttc tcaacgacag ttcacttatc aaaaaagaga cgcaacaaaa
    29461 agtccagcaa gccattgaac aattaggcta tgtctataac cgttttgctg ccaatctgcg
    29521 ttcgcaaaaa tcgctaacta tcggcgtagt cattgacgat ttgataaatc ctttcttcgc
    29581 tgaatttact atgggtcttg agatgacgct ggcggagcac ggttttatca ccgtgatgtc
    29641 caatacctcc cagcgtagtg accggcaaaa acaggtgctt gataccttgc tggaacacca
    29701 cgtcgcgggc attgtcctct gtccagtgaa cagtacctca gaagccgatt tacagcgtta
    29761 tgccaacagt tccacaccct tattaatcac gatgcgccct ctggattggc aacaattgcc
    29821 cgtcgattac gttggcgtgg acagccacgc aggtgtacgg gaagcgacgg aatatctcat
    29881 tcaacaaggg cacagagata tcgtgtttat tggtggtctt acgcaccata tgcgttatca
    29941 gggatacctt gaggcgatga atcaccatgg tttacagccg tggagtactg atgctttttc
    30001 gctgcgtgct gaaccgactc aggccaacgg ctaccagttg atgcaacagc tgttggatat
    30061 gccttcgcca cccacagcgg tgatttgtta taacgattta atggcttttg gcgcggagtc
    30121 ggcactaggc gaaagaggat tatttgccgg ggaagatatt tcgttgattg gtaatgatgg
    30181 cgtggcggct tgtgcttaca gtaacccgcc gttaaccaca attgcggtag aaccattggc
    30241 tctggggaaa caggcggcgc agcaaatttt acggcgtatt gcgcaaccag acgcaccgct
    30301 cagccattac atctatcgcc cgaccctgca aattcgcgct tccaccggaa agcgggggcg
    30361 ttaaatgctg tagcgagaaa ctgtttctcg ctatactctc ttgtccccca ttcaacagca
    30421 ggtaacacca ttcgttatgg caggcaatag acctttcaac aaacaacaga ctgataaccg
    30481 cgaacgcgat ccacaagttg ccgggctgaa agtgcctccg cactcgatcg aagcggagca
    30541 gtcggtgttg ggcggtttaa tgctggataa cgaacgctgg gatgatgtag ccgagcgtgt
    30601 ggtggcagac gatttttaca cccgcccaca ccgtcatatc tttactgaaa tggcgcgttt
    30661 gcaggaaagc ggtagtccta tcgatctgat tacccttgcg gaatcgctgg aacgccaggg
    30721 gcaactcgat agcgtcggtg gttttgctta tctggcagag ctgtcaaaaa atacgccaag
    30781 tgcggcgaac atcagtgcct atgcggatat cgtgcgcgaa cgtgccgttg tccgtgagat
    30841 gatctccgtt gcgaatgaga ttgccgaagc cggttttgat ccacaagggc gtaccagtga
    30901 agatctgctg gaccttgctg aatcccgcgt cttcaaaatt gccgaaagtc gtgcaaacaa
    30961 agacgaaggg ccgaagaaca tcgccgatgt gctcgacgca accgtggcgc gtattgagca
    31021 gttgtttcag cagccacacg atggcgttac cggggtaaac accggttatg acgatctcaa
    31081 caaaaaaacc gctggcttgc agccgtcgga tttgatcatc gttgccgcgc gtccgtcgat
    31141 gggtaaaacg acatttgcga tgaacctcgt cgaaaacgcg gcgatgttgc aggataaacc
    31201 ggtacttatc ttctcgctgg agatgccatc agaacagatt atgatgcgtt ctctggcgtc
    31261 gctgtcgcgt gttgaccaga ctaaaatccg taccgggcag ctcgatgatg aagattgggc
    31321 acgcatttcc ggcaccatgg gtattttgct cgaaaaacgc aatatctata tcgatgattc
    31381 ctccggcctg acgccaacgg aagtgcgttc ccgcgcacgc cgtattgccc gtgaacacgg
    31441 cggcatcggg cttatcatga tcgactacct gcaactgatg cgcgtaccgg cgctttccga
    31501 taaccgtacg ctggaaattg cagaaatctc ccgctcgctg aaagcactgg cgaaagaact
    31561 gaacgtgccg gtggtggcgc tgtcccagtt gaaccgttct ctggaacaac gtgccgacaa
    31621 acgcccggtc aactccgacc tgcgtgaatc tggctctatc gagcaggatg cggacttgat
    31681 catgtttatc tatcgtgatg aggtgtatca cgaaaacagt gatttaaaag gcatcgcgga
    31741 aattattatc ggtaaacaac gtaacggccc aatcgggacg gtacgcctga cctttaacgg
    31801 tcaatggtcg cgcttcgaca actatgcggg gccgcagtac gacgacgaat aataattatt
    31861 ttatgaatta ggtaattaaa gcaaacactt atcaaggaac acaaatgcaa gcggcaactg
    31921 ttgtgattaa ccgccgcgct ctgcgacaca acctgcaacg tcttcgtgaa ctggcacctg
    31981 ccagtaaaat ggttgcggtg gtgaaagcga acgcttatgg tcacggtctt cttgagaccg
    32041 cgcgaacgct ccccgatgct gacgcctttg gcgtagcccg tctcgaagaa gctctgcgac
    32101 tgcgtgcggg gggaatcacc aaacctgtac ttttactcga aggctttttt gatgccagag
    32161 atctaccgac gatttctgcg caacattttc ataccgccgt gcataacgaa gaacagcttg
    32221 ctgcgctgga agaggctaac ctggacgagc cggttaccgt ctggatgaaa ctcgataccg
    32281 gtatgcaccg tctgggcgta aggccggaac aggctgaggc gttttatcat cgtctgaccc
    32341 agtgcaaaaa cgttcgtcag ccggtgaata tcgtcagcca ttttgcgcgc gcggatgaac
    32401 caaaatgtgg cgcaaccgag aagcaactcg ctatctttaa taccttttgc gaaggcaagc
    32461 ctggtcaacg ttccattgcc gcgtcgggtg gcattttact ctggccacag tcgcattttg
    32521 actgggtgcg cccgggcatc attctttacg gcgtatctcc gctggaagat cgctccaccg
    32581 gtgccgattt tggctgtcag ccagtgatgt cgctaacctc cagcctgatt gccgtgcgtg
    32641 agcataaagc cggagagcct gtcggttatg gtggaacctg ggtaagcgaa cgtgatactc
    32701 gtcttggcgt agtcgcgatg ggctatggcg atggttatcc gcgcgccgcg ccgtccggta
    32761 cgccagtgct ggtgaacggt cgcgaagtgc cgattgtcgg gcgcgtggcg atggatatga
    32821 tctgcgtaga cttaggtcca caggcgcagg ataaagccgg ggccccggtc attttatggg
    32881 gcgaaggttt gcccgtagaa cgtatcgctg aaatgacgaa ggtaagtgct tacgaactta
    32941 ttacgcgcct gacttcaaga gtcgcgatga aatacgtgga ttaatattcg tctccaggga
    33001 gggacaatgt cttattcaga aatcgccgcg tgtctggcat acgcggtttc cgtctggctg
    33061 gctgccagaa acaatgtgca tacatggtgg atcggcataa ttggcagcat attgtacggc
    33121 tgggtttttt ggtccgtgca actctatgcc gacgttacgc tccagttatt cttcatcgtg
    33181 accagcatca ctggctggat ccactggctg aaaggtcagg gtggcgacat cttgccggtg
    33241 cgccgaacgc aagccagtca ctttttcctt ttgttgctct gtgctgtcgt cgtggcaggc
    33301 ggttacggct ttttactcca cacctttacc aatgcttggg caccctggct ggattcgttg
    33361 attttgacct tcagcgttct ggcacaattc atgttgatgg gaagacgtat cgaaaactgg
    33421 tacgtctggt tagcggtgaa taccctggcg gtgccactgt atatgacgcg cggtttaaac
    33481 ctgaccgctg gcttatattt cctgttctgg attaacgcct ggtatggttt gtatcaatgg
    33541 cgcaaagagt tgcaaacatc atgaagcctt ttgcaacggg tctggtggtt ggtaaattcg
    33601 cgcctttgca ttgtggtcat gaaaagttga tcaataccgc actggcgcaa tgtgaagaac
    33661 tgttcatcat cagttattcc gtgccggaaa tgcctgactg tgaacctgaa aagcgcctga
    33721 cgtggctgca agtgcgcttc ccgcaagcga cgtttttggt actgacgcca gagcttgttg
    33781 cgcgttataa cttacctgct atcccgcata acaatgctga tgccgacatc caccgtcatt
    33841 atgtggcgac gctatgcttg cagatattac gttgccgccc acacgctgta tttactgcag
    33901 aagactatgg cgatggcttt gctaacgtgc tggcgcggcg ttttgcccaa cccgttgaac
    33961 acgttcgaat ggcgcgccca gttggcgatg aagcgccttc gggaacgctt attcgttccg
    34021 atgttcaccg ctatcgctac atgttggcga atgatgttta ttacagtttc gttcgccgta
    34081 tctgtctgct tggtggcgaa tctaccggta aaagcacgct ttcaaaagcg ctggcgggcg
    34141 tgcttgatac ggtgtatgtc gctgaatttg gccgcgacta ttgggaagaa aaaaacggta
    34201 tcttaactgc ggatgatttg ttgcatatcg cctgcgaaca ggtacgccgg gaacaacaag
    34261 cagaagctaa tcactatctt atatgtgaca cgtcgccact cacgacctta ttctatgccc
    34321 ttgatcaata tggtcatgct ccgcaagaac ttcaccaact ggcggagcgg gaatactctc
    34381 tggtagtgct ttgcggcgca gaatttccct tcgtgcagga tggcacccgg caaggagagg
    34441 tatttcgcgc acggcaacag gtgtggtatg aacaggaatt gtcgcgcagg aacattcctt
    34501 atctttcggt ttcggggcca ctgcaagagc gagtggagca aattcttcgc caacttcccg
    34561 actgactttg aacatcctct cgatcttcgc cttcttccgg tttattgtgg tttaaccacc
    34621 tgcccgtaaa cctggagaac catcgcgtgt ttcaaaaagt tgacgcctac gctggcgacc
    34681 cgattcttac gcttatggag cgttttaaag aagaccctcg cagcgacaaa gtgaatttaa
    34741 gtatcggtct gtactacaac gaagacggaa ttattccaca actgaaagcc gtggcggatg
    34801 cggaagcgcg cctgaatgcg cagcctcatg gtgcttcgct ttatttaccg atggaagggc
    34861 ttaacagcta tcgccatgcc attgcgccgc tgctgtttgg tgcggaccat ccggtactgc
    34921 aacaacagcg cgtagcaacc attcaaaccc ttggcggctc aggggcattg aaagtgggcg
    34981 cagatttcct gaaacgctac ttcccggaat caagcgtctg ggtcagcgat cctacctggg
    35041 aaaaccacgt agcaatattc gccggggctg gattcgaagt aagtacttac ccctggtatg
    35101 acgaagcgac taacggcgtg cgctttaatg acctgttggc gacgctgaaa acattacctg
    35161 cccgcagtat tgtgttgctg catccatgtt gccacaaccc aacgggtgcc gatctcacta
    35221 atgagcagtg ggatgcggtg attgaaattc tcaaagcccg tgagcttatc ccatttcttg
    35281 atattgccta tcaaggattt ggtgccggta tggaagagga tgcctacgcc attcgcgcca
    35341 ttgccagcgc tggattaccc gctctggtga gcaattcgtt ctcgaaaatt ttctcccttt
    35401 acggcgagcg cgtcggcgga ctttctgttc tgtgtgaaga tgccgaagcc gcaggccgcg
    35461 tactggggca attgaaagca actgttcgcc gcaactactc cagcccgccg aattttggtg
    35521 cgcaggtggt ggctgcggtg ctgaatgacg aggcattgaa agccagctgg ctggtggaag
    35581 tagaagagat gcgaactcgc attctggcaa tgcgtcagga actggtgaag gtattgagca
    35641 cagagatgcc agaacgcaat ttcgattatc tgcttaatca gcgcggcatg ttcagttata
    35701 ccggtttaag tgccgctcag gttgaccaac tacgtgaaga atttggtgtc tatctcatcg
    35761 ccagcggtcg catgtgtgtc gccgggctta acacgcaaaa tgtgcatcgc gtggcaaagg
    35821 cgtttgctgc ggtgatgtga ttttaatcaa caggcggatc tctccgcctg ttcctgactc
    35881 cagccactcc ctactatttt gtcccttttt tcgcccactt ttacatcatc tcttttctat
    35941 aagtttttga aaattagtgt ttttaactgt tggtacggat tgtgcagtaa tgcagctgtc
    36001 tatgaccatc aggagaaaaa catggagaac atgacctcgc ccggcacgct gcttagtgga
    36061 gataacgcga cctggcttga agagtactac cagacctggt tgcgtacgcc ggaacaactc
    36121 ccggaagact ggcggcgttt ttttctttca cctgaactga ctgtccaaag cgtatccggt
    36181 gataacaata tcagcggtgc gaccttaaaa aaacaggctg cggtaataca actgatcaat
    36241 gcctggcgca cgcaggggca tctgcgcgca aagcttgatc cacttggttt gaatcccccg
    36301 gctgacgttc cctccctcca gcctggtttt tggggattaa gcgaagaaga cttgttgcag
    36361 gagtttagcg tcacctttgg cgcacacacc acgcaaatgc cacttaagca actgcttaac
    36421 ctgctggagc aagcctgggc cagtagccag gcttatgaac ttgctcatct ggaaaatcgt
    36481 gaagaaatca actggttgtt atcacggatt gagagcagca atgcgccaca agctgatgcc
    36541 caaacctgta ttgctcgttt tgaaaaactg atggcggcag agacgttaga gcgttatctg
    36601 catacccgtt atgttgggca gaaacggttt tctctggaag ggggcgaaag tgcaatcccg
    36661 gcgctcgata cgctgacaaa acgcctgcgt gcgcaaggtg tggaggaaat ggtcattggc
    36721 atggcgcacc ggggaagact taatgttctg gttaatctgt tgaataaaga cccggcacag
    36781 ctttttgctg agtttgaagg caagcagacg atcggcagtg gttcaggcga tgtgaaatac
    36841 cacatggggt attccagcaa tctggaaaca cctgccggtt cgctgcatgt ggcgctggcg
    36901 tataacccct cacatctgga gatcgtgaat ccggtggtgc tgggccaggt gcgagccagg
    36961 caggaacgcc gtggtgagga tggtcaggca aaagtggtgg gcgtacttat tcatggggat
    37021 tccgcgttgg gcggcctcgg cgtcaaccaa accacgttta acttatcgca gactcagggc
    37081 tacggcactg gcggtacgct acatctggtg attaacaatc agattggctt caccacttcc
    37141 cgcttgcagg atatgcgttc ttcacggtac tgcaccgata ttgccaaaat ggtagcggcc
    37201 ccaattatcc acgttaatgg cgatgacgtt gacgctgttt gccaggtaat ggaactggcg
    37261 tgcgaatggc gagacacctt ccggcgtgac atcatcatcg atatttgctg cttccgtaag
    37321 cacggacaca acgaaagcga tgagccacgt cttacccagc cacaaatgta tcaggcagtg
    37381 gatgctcacc ctggtacgct cgcccgttat ggtgaatctc ttgcccgccg cggcctgtta
    37441 actcaggcgc aacaagatga gatgacggca cgctatcgcg actggctgga tagctgccag
    37501 aaacgtgaac cgcagcctct caaacctgca attcactctt ttagcgctaa ctggtatggg
    37561 ttgaccaacc ctcactggag cgccccggta tctacggcat tgcctcggca aaagctggca
    37621 gcgtatggtg aaatcatttc tacactgcca cccgatgtgg tcgcacatcc taccattaaa
    37681 cggcaactgg cgttacgcca ggatatggcc gcaggtactc agccagtaga ctggggaatg
    37741 gctgaaatgc tggcctatgc atcgcttgtg gatgcgggtg ttggtgtgcg tctttctggt
    37801 gaagactcag ggcgtggcac gttcagtcat cgccatgcag tggtacatca tcaaacggaa
    37861 gcccgtcgtt atctgccgtt acagcatatc cgcgctggtc aggcatcttt cgatgtttat
    37921 gattcggtgc ttaatgaaga agcgctctta gcctttgaat atggctattc aacgtctgcg
    37981 cctcagcaac tggttatttg ggaagcacag tttggtgact ttgccaacgg cgctcaggtt
    38041 gctattgacc aatttatctc gtctggcgaa accaagtggg atcgctatag cggtttaacc
    38101 attcttctgc cgcatggcta tgacggacaa gggccggagc actcttccgc acgtcctgag
    38161 cgctggctgc aactgtgcgc agaaaacaac atgcaggtgg tgatgcccag tgagtcagca
    38221 caaatgttcc atttgttgcg cggtcaggca ttacgcccaa tgcgcaaacc gttagtgata
    38281 atgatgagta agcgtttact tcggtttaaa ggcgcgatga gcgagctttg tgaattcact
    38341 gatgacgctt ataaaccggt aatcaccgat ccgcaattgc atcagtccca gaaagttaag
    38401 cgcgttattt tgtgtagcgg ccaggtctat tacgacgtac tggaagcccg taagcagcgt
    38461 gagcatgaag acgaggtagc gattgttcgc ctggagcaac tctacccgtt cccggtcgca
    38521 gaactgaatg atgttctggc gagttggccg aactgctgcg aatggatttg gttgcaggaa
    38581 gagccagaaa accagggcgc gtggcggcag attcgtcatg agctggcggc actgaaaatt
    38641 aacactcctt actggcagta tgcaggccgc ccggcagcgg cagcaccagc gacagggtat
    38701 gggcgtgtac ataaacaaca aatcgacgaa tttcttgctg ctgcgtttgc agatattcag
    38761 ccatgaaagg cgcacaaaaa taataaggag aacattttat gatcgaaatt actgtccctg
    38821 tattaccgga atctgtcacg gaaggcacgc tgacaacctg gtgtaaacaa gaaggcgagc
    38881 acgtaaaacg cgatgatgtg attgccgagc tggaaaccga taaagtcatt ctggaaatac
    38941 cggccccgca cgatggcgtg ttaagcaata ttatcgtcag cgaaggtagc acggtcacgt
    39001 ccgcgcaact gttggcgcat cttaagccgc aagctgtcat agaagaaacc gtcacaccag
    39061 tcaccgaaac cctggcgatg ccttccgcac ggctggaggc acagcgtagt ggtgtcgaac
    39121 ttgctgacgt tgcggggagc gggagaaatg gacgtatcct gaaagaggat gtgcagcgcg
    39181 ttactcctgc accagccatt cagcctgaac gggtggcgga gatcgcgcca gctaaaccct
    39241 tgacaccggg tgctcgtcag gaacgtcgtg agccgatgtc gcgcttacgt cagcgaattg
    39301 ctgagcgtct gctggcttcc caacaaaata acgccattct taccacattc aacgaagtaa
    39361 acatgcagag cgtgatggac ttacgcgccc gctggaaaga tcgttttgcc gagaagcacg
    39421 gcgtgaagct gggctttatg tccttctttg ttaaggccgt tacccgggcg ctggagcgct
    39481 tccctgtagt gaatgccagc gtcgatggca acgagattat ctggcgtgat tattgcgata
    39541 tcggcattgc agtgagcagc aaccgcggcc tggtagtgcc tgtgttacgc aatgcgcaat
    39601 cactctcttt ggtggaaatt gaacggcaaa ttgccgaata cgccacacag gcacgcaatg
    39661 gcaaattgcc gctggaggcg ttacagggcg gcacgttctc tatcaccaac ggcggtactt
    39721 ttggttcgat gatgtcaacg ccaatcatta acccgccgca gtcggccatt cttgggatgc
    39781 atgccatcac gccgcgcccg gtcgcagaaa acggtcaggt tgttattcgt cccatgatgt
    39841 accttgctct cagctatgac catcgcatta tcgatggtca ggaagccgtg catacattgg
    39901 tggcaatacg tgagctactg gaatcaccgg aacaactgtt gctggatctt taaggagggc
    39961 gccgatgagt acaatttttg atgtggcagt tatggggggg ggggccaggt ggttacgtag
    40021 cggcactgcg ggctgcgcag aatgggcttt ccgtagtatg tattgatgat ggtgttaatg
    40081 cacagggcga accttcgccg ggcggtacgt gtctcaatgt cggctgtatt ccgtcaaaat
    40141 cgttgctgca atcttccgaa ctgtacgcgc aagtgcagca tgaggcgagc attcatggcg
    40201 ttaatgttga cggcgtatct ttcaatgcag ctgcgatgat tcaacgtaaa gacgccatag
    40261 taagccgcct gacaatgggc atcagcttgc tgtttaagaa aaataaagtg aagcacctgt
    40321 gcggcctcgc aacgttagaa tgtgctcagg atgagatttg gcaattacgt gtaaacgatc
    40381 aacaccttca cgcccgtaat gtagtgattg caacaggttc tcagccgcgt cagctgcctg
    40441 gcgttaccat tgataatcaa cagatcctcg acaatcgtgg cgccctggca ttgagcgaag
    40501 tgccgccgcg tctcggtgtg atcggcgctg gcgtgattgg ccttgaactg gggtctgtgt
    40561 ggaatcgggt tggttcagac gtcacgttgc tggagatggc gccaacgttc ttgcctgcac
    40621 tggaagctcg cctgtcgaac gaagtccgta aagcaatgat tgccagtggg atgaaaatgc
    40681 aactggcagt agagattgag gctattgaac aacgggatga cggtgtgcat gtgcgctggc
    40741 ggcagggtga gaagcgagaa gaaagccgct tcgataaatt aattcttgcc attggacgtg
    40801 taccgcgact ttctggtgtc gatctcgtgc aactcggtct tgaagccgat aaccgtggcg
    40861 gtattgccgt cgataactta tgccgtaccg ggaaagccgg gctgtgggca attggtgatg
    40921 tcgtgcgagg gccgatgctg gcgcataaag cgatggctga aggtgtagtg gtggctgatc
    40981 aaattgccgg actggtggta gagccgatta attttgcgct gatcccttcg gtgatttaca
    41041 cccaaccgga agttgcgtgg gtaggggaaa acgaggcctc actgaaagcc gctggcagag
    41101 tctttaacaa aggaaattct ctgtttgccg gtaacggtcg cgccttagca ttaggccagg
    41161 aaggtgggcg ttgcacgtta tacagtgata aacacactga ccgcgtactt ggcggagcga
    41221 ttgttggccc gcaggcatcg gagctgatta atgaaattgc gctggcgatg acttttagcg
    41281 cctctggcga ggatattgcc tgtgcgatcc atgcgcatcc gacattaagc gaagtcatcc
    41341 acgaagcagc aatggccttg aataataaag cattacacgg ataacacaca ccactgaggg
    41401 aatatatgaa tttacatgag tatcaggcca aatcgttact ggctggcatg gggatgccgt
    41461 gtccaaaaga gatagctatc caacagattt cgcaactggc agatgcctgg caacatattg
    41521 cttgcccgag taaaggcgcg gtacttaaag cgcaggtaca tgctggtggg cgcggtaaag
    41581 ctggcggcgt aaaagtgctt aagcagctgc cggaagcaca ggcttttgta cagcaaatgt
    41641 tgggatcgca actggtgact tatcagaccg ggccagaagg acagtatgtc agcagtattt
    41701 tactgtgcga aaacatttat ccggtacgcc aggaactcta ttttggcatg gtggtggatc
    41761 gtgaaagcca gcgggtcacg tttattgtca gcccggaagg tggtgtggaa attgaaaaag
    41821 tcgcccatga gacaccggag aaaatcagca gtgtcagcat tgatccactg acaggcgtgc
    41881 agccttgcca tatccgcgaa atgtttgctg ttctgcaact ggaacacgga ctatttgctg
    41941 cctttagtcg cctggttaat caggcgtgga aagcctttaa cgaactggat tttgccctgc
    42001 tggaaattaa ccctctggtg ttgcgggaaa cgggcgaatt tatgtgtgca gacgcgaaag
    42061 tatcgctgga tgataacgcg ctgtatcgtc acccggaact ccaggtgcta cgtgatgaaa
    42121 cccaggaaga tccacgcgaa agccaggcag cgaagcttga tcttaattat gtctcgctgg
    42181 acggaaatat cggctgcatg gtcaatggtg cagggctggc tatggcaacc atggacatca
    42241 tcaagctata cggtgaacaa cccgcaaact tcctggatgt tggcggtggc gcaacccagg
    42301 agcgcgtcag tgaagccttt cggctgattg tttccgacag caaagtgaaa gccattctgg
    42361 ttaatatttt tggtgggatt gtccgttgcg acatgatcgc cagagccatt attcatgctc
    42421 tgaatgaggc cagcatcacc ctgcctgtcg tggtgcgtct ctccggtaat aacgccgccg
    42481 aagggcagcg gttactggca gaaagtggtc tgacggtgga agccgtcgat tctctggatg
    42541 atgccgcgaa acgcatcatt gcgttactga attaacagga ggttaagatg agcgttttga
    42601 tcaacaaaca cacgcgggta ctggtgcagg gcattaccgg caaaaacggc acatttcata
    42661 cagagcaggc tattgcgtat ggcacgcaga ttgtgggtgg agtgacgcct ggtaagggcg
    42721 ggcaacggca tctggatcgc ccggtttttg attcaatgaa agatgcgatg cgacaaactg
    42781 aggccgatgc cagcgtgatt tatgtgcctg caccgtttgt gctggattct gttgttgagg
    42841 ctattgaagc tggcgtcaaa ttggttgtgg tgatcactga aggtgtaccg acactggata
    42901 tggtgaaagt tcgtcggctg cttgactgcc acccggatgt gcggctgatt gggccaaact
    42961 gcccaggagt tatcacgccg ggtgagtgca aaatcgggat tatgcctggt gaaatccacc
    43021 gcccagggcg tattgggatt gtttcccgct ccggtacatt aacctacgaa gctgtagcgc
    43081 aaaccacggc gctgggactt gggcaatcca cctgtattgg tattggcggc gatccggttc
    43141 cggggactaa ctttattgat gcgctgcgtt tattcgaaaa tgatccgcaa acagacgcgg
    43201 taattatgat cggtgaaatt ggtggtaatg cggaagaacg ggccgcggaa tttattcgcc
    43261 atgatatgaa taaaccggtc gtaggttata ttgccggtgt tactgcacca aaaggaaaac
    43321 gcatgggaca cgccggagcc attatttctg gcggtagcgg cagtgcagag gataaattcc
    43381 gtgcgttcga taaagcaggc atggcatgga caagaaaccc ggcgttgctt ggcgaaacgt
    43441 tatggaatgt tattaagtaa tccataaatg aatatcaagg gagcatatcg ctcccttttt
    43501 ttatctgtgt ggtaagagaa tcacctttta tttactgtgc ggaaaaccgc gca
//
LOCUS       DAPOXO010000037        43452 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPOXO010000037 DAPOXO010000000
VERSION     DAPOXO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43452
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.037"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            1166..1342
                     /locus_tag="ROH59_002392"
     CDS             1166..1342
                     /locus_tag="ROH59_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016158417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804866.1"
                     /translation="MKKTFTFSLLAIVFASLLSACVPHHHHRHSDGPRGPAPSGKPMP
                     PSNGGPNHGSHGRY"
     gene            complement(1379..3298)
                     /gene="dhaR"
                     /locus_tag="ROH59_002393"
     CDS             complement(1379..3298)
                     /gene="dhaR"
                     /locus_tag="ROH59_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001467850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase operon
                     transcriptional regulator DhaR"
                     /protein_id="HDX4804867.1"
                     /translation="MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFA
                     SIYRRKKAMLTLGQAALEDAWEYMAPRECALLILDETACILSRNGDPQTLQQLSVLGF
                     NDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQALWNWAFCATPLFDSKGRLTGT
                     IALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVIS
                     WDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFE
                     SQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQT
                     RRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAAL
                     AEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDA
                     RRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNN
                     KLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPE
                     HLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRK
                     MKQHGIDAGQFKRRG"
     gene            3526..4596
                     /gene="dhaK"
                     /locus_tag="ROH59_002394"
     CDS             3526..4596
                     /gene="dhaK"
                     /locus_tag="ROH59_002394"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309732.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDX4804868.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQIDGGEGVLLI
                     IKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRPFSSLDQTVDEMFDTLLENGSYHRTLRLWDYQQGSWQEEPQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            4607..5239
                     /gene="dhaL"
                     /locus_tag="ROH59_002395"
     CDS             4607..5239
                     /gene="dhaL"
                     /locus_tag="ROH59_002395"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase ADP-binding subunit
                     DhaL"
                     /protein_id="HDX4804869.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFGKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQTTQARQSLT
                     LEELYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSCEQNLSVPAALDAASS
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            5250..6668
                     /gene="dhaM"
                     /locus_tag="ROH59_002396"
     CDS             5250..6668
                     /gene="dhaM"
                     /locus_tag="ROH59_002396"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaM"
                     /protein_id="HDX4804870.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDNCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPEIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTEISDTCPPYDEEARSLAV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTL
                     TVEEEQERLRQAIDFTLLDLMTLTAKAETSGLDDIAAIFSGHHTLLDDPELQAAASEL
                     LQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGTPLSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKTQRFNRQG"
     gene            6988..8685
                     /gene="treA"
                     /locus_tag="ROH59_002397"
     CDS             6988..8685
                     /gene="treA"
                     /locus_tag="ROH59_002397"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDX4804871.1"
                     /translation="MKSPAPSRPQKMALIPACIFLCFAALSVQAEETSVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPK
                     EGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPKPYVVPGGRFREVYYWD
                     SYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELL
                     AQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTP
                     RPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVP
                     VDLNSLMFKMEKILARASKAIGDNAMANQYETLANARQKGIEKYLWNDQQSWYADYDL
                     KSHKVRNQLTAAALFPLYVNAAAKDRASKMATATKTHLLQPGGLNTTSVKSGQQWDAP
                     NGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGG
                     GGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPLSESTTQPLKQKEAEPTP"
     gene            9015..10037
                     /locus_tag="ROH59_002398"
     CDS             9015..10037
                     /locus_tag="ROH59_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HDX4804872.1"
                     /translation="MSLTRRRFTQILASTLFLHHLPSFAQSVKFWASLTLPEAQHITR
                     IVSAGAPADLLLLAVAPEKMVGFSSFDFARQALIPLPEHIRQFPRLGRLAGRASTLSL
                     EGLMALHPDLVVDCGNTDETWISQARQVSEQTQIPWLLLNGKLEQSAEQLTTLGKTLG
                     EEHRAAEQANLASRFVGEAQAFATSPAANLSFYAARGPRGLETGLQGSLHTEAAELLG
                     LHNVAQIADRHGLTQVSMENLLRWQPDIILVQEAVTADFIRRDPLWQGVKAVAEQRIL
                     FLSGLPFGWLDAPPGINRLLGLRRLHAWLDPAINRQFKSDMQHYAQLFWHCSLSDADY
                     QKLVAS"
     gene            10037..11017
                     /locus_tag="ROH59_002399"
     CDS             10037..11017
                     /locus_tag="ROH59_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDX4804873.1"
                     /translation="MRTVNGCILLLAAISITFAAVSGAYHLDMQQLLALILRQENVPV
                     QEQIVFWQIRVPRILAALFLGAALAGAGTTYQGMFRNPLVSPDILGVSAGAGLGACAA
                     ILWGLSIVYIQLYAFCGGLMVVAGVWLITRRVTRHDPILTLVLVGIALGTLCGAGISL
                     IKTLADPYTQLPSITFWLLGGLSTVTLRDLCYAAPIILIGSLPLFFLRWRMNLLTLSD
                     DEARSLGLNVTRLRFGLIVCATLITASTVAIAGIIGWVGLVVPHIARLLTGHNHQQLL
                     PMAMCTGAILLLLTDTLARSIGTTEIPLGILTAFVGAPFFLFLLLRGGRQ"
     gene            11014..11772
                     /locus_tag="ROH59_002400"
     CDS             11014..11772
                     /locus_tag="ROH59_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4804874.1"
                     /translation="MTLLAVRHASLGYSRHPVLRDVSFTLSQGTICCLLGANGCGKTT
                     LMRSILGVIPLLKGEILLDSLPVQTLSHRQRAQAIAWVPQAHDGIFAFSVLDMVLMGL
                     APTIGAFSVPGKQERLKATEQLEKLGILHLATRRWNTLSGGERQLALIARALVQQPRL
                     LLLDEPASSLDFGHQIQLLDTLAQLKNNGMTMLMSTHHPLHANAIADSIIQVEPDGRV
                     TQGLPTEQLTTKKLAALYRVSADQIHHHLSAIKH"
     gene            11782..12594
                     /locus_tag="ROH59_002401"
     CDS             11782..12594
                     /locus_tag="ROH59_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDX4804875.1"
                     /translation="MLIDDIDFADLYLQQLRLAHRTEKTPDHWDQRAEKMAENCASPT
                     DSYLQQLTSKIDLQGAQTLFDMGCGPGTVSLALADKLTTIYGVDYSQGMLNVAARRAA
                     ALKADNVHWIQRAWEEDWSDLPRCDIAVASRSTLVADMRQAMSKLNNQARLRVYTTHL
                     VSTSFVSPAIQRAAGREVIELPNYIFALNVLYQMGIYAHVDFIRGQNCQQDNSTWERF
                     EQNVSWSLGALNDDERERLYRWYQQQDARALAPASRDWALIWWDSVPQETLR"
     gene            12591..13445
                     /locus_tag="ROH59_002402"
     CDS             12591..13445
                     /locus_tag="ROH59_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ModD protein"
                     /protein_id="HDX4804876.1"
                     /translation="MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGG
                     CISGISVACKMLTTLGLTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEW
                     SCGVSDYLAQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETI
                     LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKF
                     SPQQATEIAQIAPSLAPHCTLALTGGINLTTLKNYLDCGIRLFITSAPYYATPADIKV
                     SLQPAASI"
     gene            13471..15441
                     /locus_tag="ROH59_002403"
     CDS             13471..15441
                     /locus_tag="ROH59_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDX4804877.1"
                     /translation="MRLKKRYLCTALSLAFTQQAVAAQESDTLTVWSSPVSSTTTTVL
                     DQPTMKALDKQNVAQALSVVPGVVLQKSGSRNEEQVKVRGFDSRQVPVYFDGVPIYVP
                     YDGNLDLARILTNNLGAVEVSKGYSSLLQGPNQMGGAINITTQKPTKPLEASLGYRQG
                     WSRSQDNAYDMHASFAASSDLGYLQVSGSQLKQDFLGLPHGVNNDIAGKHGKMINSSA
                     DDKRGIVKLGFTPRENDEYTLTYIKQDGEKDNPPYSGNSGQKSRYWQWPEYDKESFYY
                     QGTTQLNDRFTLKSRLYRDTFENTLMMYNSLADLKNKKGSYSHYSDYSDGAGLQLAAD
                     VRENDLLSFAVNWKDDVHREKGAPHAAYDRYEDRTWSLASEYQWAAADNVDVVAGISY
                     DWRDSVEAKKHEKDGSITHYDDNNQSAFNWQVMGKYHFANEDTLALSYYDRTRFPTLK
                     ERYTTSKPAYNQIAIVNPQLKPERARGVDLTWNGAFTHDWGFEVSVYYNRVSDAILSH
                     NIDADTIQNQNSGTVDYSGLDAGIKGKISNILDVGLSYALIHADAKRKDIGKITDLPT
                     QTMTAWMTLKPWEPLSVTLSEEARSSSYSNSDGSQKAAGFAVTHIRADYTLGHGFSVN
                     ASVNNLFDTKYAYSEGFIEEGRNFWAGIEYTF"
     gene            complement(15491..15745)
                     /locus_tag="ROH59_002404"
     CDS             complement(15491..15745)
                     /locus_tag="ROH59_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDX4804878.1"
                     /translation="MGIIAWIIFGLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAILVLGVFRLLRRE"
     gene            15946..16680
                     /locus_tag="ROH59_002405"
     CDS             15946..16680
                     /locus_tag="ROH59_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HDX4804879.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLNKAAIPLRISWNGGQLISKIL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRITAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AELHEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREARKKADNVRD"
     gene            complement(16682..17293)
                     /gene="emtA"
                     /locus_tag="ROH59_002406"
     CDS             complement(16682..17293)
                     /gene="emtA"
                     /locus_tag="ROH59_002406"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309714.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HDX4804880.1"
                     /translation="MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQIKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM"
     gene            17393..18307
                     /gene="ldcA"
                     /locus_tag="ROH59_002407"
     CDS             17393..18307
                     /gene="ldcA"
                     /locus_tag="ROH59_002407"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HDX4804881.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIQRLTDAGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAQGNVITFSGPMLVANFGADELNAFTEHHFWLALRNKTFTIEWQ
                     GEGPTCQTEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAHAILNNTEEGTQLTISGHPVLKM"
     gene            18402..20138
                     /locus_tag="ROH59_002408"
     CDS             18402..20138
                     /locus_tag="ROH59_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDX4804882.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIAL
                     PAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            complement(20195..21265)
                     /gene="dadX"
                     /locus_tag="ROH59_002409"
     CDS             complement(20195..21265)
                     /gene="dadX"
                     /locus_tag="ROH59_002409"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309712.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HDX4804883.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIE
                     RIWSALGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISSAMARIEQAAEGLECRRSLSNSAATLWHQEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(21275..22573)
                     /gene="dadA"
                     /locus_tag="ROH59_002410"
     CDS             complement(21275..22573)
                     /gene="dadA"
                     /locus_tag="ROH59_002410"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HDX4804884.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVDQAAFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEALSVARYSRGFTPSRPGHLHGAHS"
     gene            22903..24435
                     /locus_tag="ROH59_002411"
     CDS             22903..24435
                     /locus_tag="ROH59_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HDX4804885.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSIELLERCPPRMG
                     NL"
     gene            complement(24487..25206)
                     /gene="fadR"
                     /locus_tag="ROH59_002412"
     CDS             complement(24487..25206)
                     /gene="fadR"
                     /locus_tag="ROH59_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HDX4804886.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            25428..26969
                     /gene="nhaB"
                     /locus_tag="ROH59_002413"
     CDS             25428..26969
                     /gene="nhaB"
                     /locus_tag="ROH59_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HDX4804887.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAALLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKV
                     REVLQQFDDQSRNQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTVAGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            27115..27645
                     /gene="dsbB"
                     /locus_tag="ROH59_002414"
     CDS             27115..27645
                     /gene="dsbB"
                     /locus_tag="ROH59_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HDX4804888.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMARFPEWLPLDKWVPQVFVASGDCAERQWEFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(27690..28958)
                     /gene="umuC"
                     /locus_tag="ROH59_002415"
     CDS             complement(27690..28958)
                     /gene="umuC"
                     /locus_tag="ROH59_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V catalytic protein"
                     /protein_id="HDX4804889.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVHNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDEVWGIGRRISKKLDAMGIKTVLDLADSDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFAFNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFA
                     GQGIQQQWQMKRAMLSPCYTTRSSDLLRVK"
     gene            complement(28958..29377)
                     /locus_tag="ROH59_002416"
     CDS             complement(28958..29377)
                     /locus_tag="ROH59_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HDX4804890.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIIIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            29574..29963
                     /locus_tag="ROH59_002417"
     CDS             29574..29963
                     /locus_tag="ROH59_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin E"
                     /protein_id="HDX4804891.1"
                     /translation="MEAFAQKGILIKVLDDGIKKLCSIAAGVVEGKLIPELKNKLKSV
                     QSFFTTLSNTVKQANKDIDAAKLKLTTEIAAIGEIKTETETARFYVDYDDLMLSLLKE
                     AAQKMINTCNEYQKRHGKKTLFEIPEV"
     gene            complement(30170..30616)
                     /locus_tag="ROH59_002418"
     CDS             complement(30170..30616)
                     /locus_tag="ROH59_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HDX4804892.1"
                     /translation="MSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKGL
                     PAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(30708..31367)
                     /locus_tag="ROH59_002419"
     CDS             complement(30708..31367)
                     /locus_tag="ROH59_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDX4804893.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLGLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKVGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            complement(31439..31732)
                     /locus_tag="ROH59_002420"
     CDS             complement(31439..31732)
                     /locus_tag="ROH59_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HDX4804894.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            31973..32374
                     /locus_tag="ROH59_002421"
     CDS             31973..32374
                     /locus_tag="ROH59_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PPC domain-containing protein"
                     /protein_id="HDX4804895.1"
                     /translation="MKIKGISKAVLLLALLTSTSFAAGKNVNVEFRKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYSLP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            complement(32477..32845)
                     /locus_tag="ROH59_002422"
     CDS             complement(32477..32845)
                     /locus_tag="ROH59_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804896.1"
                     /translation="MNMMRIFYIGLSGVGMMFSSMASGNDAGGLQSPACGVVCDPYIC
                     VSSDGISPELTRKYLGEKAAENLQSLQGYDPSEFTFSNGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQTTTKMLFMCRE"
     gene            33365..34060
                     /gene="minC"
                     /locus_tag="ROH59_002423"
     CDS             33365..34060
                     /gene="minC"
                     /locus_tag="ROH59_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDX4804897.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKSPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            34084..34896
                     /gene="minD"
                     /locus_tag="ROH59_002424"
     CDS             34084..34896
                     /gene="minD"
                     /locus_tag="ROH59_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDX4804898.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            34900..35166
                     /gene="minE"
                     /locus_tag="ROH59_002425"
     CDS             34900..35166
                     /gene="minE"
                     /locus_tag="ROH59_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDX4804899.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(35533..35875)
                     /locus_tag="ROH59_002426"
                     /pseudo
     CDS             complement(35533..35875)
                     /locus_tag="ROH59_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(35910..36029)
                     /locus_tag="ROH59_002427"
     CDS             complement(35910..36029)
                     /locus_tag="ROH59_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDX4804900.1"
                     /translation="MPLSYTGYHHFIMMSLMSGEHNTFALSLQDESPGLVPAG"
     gene            complement(35990..36174)
                     /locus_tag="ROH59_002428"
                     /pseudo
     CDS             complement(35990..36174)
                     /locus_tag="ROH59_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36275..36448
                     /locus_tag="ROH59_002429"
     CDS             36275..36448
                     /locus_tag="ROH59_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804901.1"
                     /translation="MSYFSFEIILIPVKNIIPIITVTLILNYLNNSERSLVKQILIED
                     EIIVCATYLIPDN"
     gene            36450..36794
                     /locus_tag="ROH59_002430"
     CDS             36450..36794
                     /locus_tag="ROH59_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415690.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HDX4804902.1"
                     /translation="MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNG
                     VNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVI
                     GGTGGAILGKMK"
     gene            36798..37133
                     /locus_tag="ROH59_002431"
     CDS             36798..37133
                     /locus_tag="ROH59_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmgD family protein"
                     /protein_id="HDX4804903.1"
                     /translation="MMMKKFALLAGLFVFAPMTWAQDYNIKNGLPSETYITCAEANEM
                     AKTDSAQVAEIVAVMGNASVASRDLKIEQSPELSAKVVEKLNQVCAKDPQMLLITAID
                     DTMRAIGKK"
     gene            complement(37192..38698)
                     /locus_tag="ROH59_002432"
                     /pseudo
     CDS             complement(37192..38698)
                     /locus_tag="ROH59_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768542.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(38861..39013)
                     /locus_tag="ROH59_002433"
     CDS             complement(38861..39013)
                     /locus_tag="ROH59_002433"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804904.1"
                     /translation="MQIVVNPGVITVVLYISEIISMATVDNFDVEELFVKQNSYPKVI
                     NVMKIS"
     gene            complement(39096..39314)
                     /locus_tag="ROH59_002434"
     CDS             complement(39096..39314)
                     /locus_tag="ROH59_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804905.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVSHRDQH"
     gene            complement(39446..40339)
                     /locus_tag="ROH59_002435"
                     /pseudo
     CDS             complement(39446..40339)
                     /locus_tag="ROH59_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415686.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(40637..40885)
                     /locus_tag="ROH59_002436"
     CDS             complement(40637..40885)
                     /locus_tag="ROH59_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804906.1"
                     /translation="MNNSIPERFIFQCALFKNLEKEVFMTHGYVDSHIIAHALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVLS"
     gene            complement(40998..41264)
                     /gene="ariR"
                     /locus_tag="ROH59_002437"
     CDS             complement(40998..41264)
                     /gene="ariR"
                     /locus_tag="ROH59_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm/acid-resistance regulator AriR"
                     /protein_id="HDX4804907.1"
                     /translation="MLEDTTIHNAISDKALSSYFRSSGNLLEEESAVLGQAVTNLMLS
                     GDNVNNKNIILSLIHSLETTSDILKADVIRKTLEIVLRYTADDM"
     gene            complement(41293..41565)
                     /locus_tag="ROH59_002438"
     CDS             complement(41293..41565)
                     /locus_tag="ROH59_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HDX4804908.1"
                     /translation="MKTSDNESIKYEITGQAVLQILRMKINFSLQTLIKQLLVMKSAE
                     ENTFRRDLIDSIIRDFSNSDTGGPNRRTAIADNKNMFTGKKINRIH"
     gene            complement(41608..41844)
                     /locus_tag="ROH59_002439"
     CDS             complement(41608..41844)
                     /locus_tag="ROH59_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YcgZ"
                     /protein_id="HDX4804909.1"
                     /translation="MHQNSVTSDSAGAITRYFAKANLPTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLCRLEQATGEEEQKHYNALIGLLFE"
     gene            42158..43369
                     /gene="bluF"
                     /locus_tag="ROH59_002440"
     CDS             42158..43369
                     /gene="bluF"
                     /locus_tag="ROH59_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HDX4804910.1"
                     /translation="MLTTLIYRSHIRDAEPVKKIEEMVSIANRRNMRSDVTGILLFNG
                     SHFFQLLEGPEEQVQMIYRAICQDPRHYNIVELLCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQSTYFEIPAEDSWLFIADGSDKE
                     LDSCTLSSNINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKEGEIYTAD
                     LKSKALAFAMAHALKLGDKMISINLLPMTLVNEPDAVSFLLDEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAVKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIMKCCTSLEIQVSAMGVATPEEWMWLESAGIEMFQGDLFSKAKLN
                     GIPSVAWPEKK"
BASE COUNT        11253 a        10811 c        10187 g        11201 t
ORIGIN      
        1 aaatgtaact ttaatctgaa gcaaatcagc cagttcaaat ttgttacaac aagcctgcag
       61 ccttgccaga taggtaggtt taaacataac agtaaattcc attattgatt atgttaatgc
      121 acatgcaggt actcttacgc atttaacggt gacgccaaga tgacttgacg gcagtcagag
      181 ggcgaatact cccgaccttg ttaacactga ttgcgatacc acaaccaaca aatctacctg
      241 catgtgccgt attaaattag catagtcatc atataactca agcccccaat caattttttt
      301 caaaatcctc aataagttat agatggtttg cgttctgttc atttctggca tcagagtgat
      361 gattaggcaa gttagctggg aaaatttatc cggagtatat acaaagaaag tagtcagccc
      421 agttgaatca tctaaacaag accaattaac taatttattt aaatgaaaaa taatgctttt
      481 gagctaacca attatgcact taagctaaat ttaccgtttt tggggctagc ccaacatcga
      541 gggcgcataa gctttagccc acttttactt tcctgttttc tttagtaaca gaaggttaac
      601 tatcaaatat ttttgttggg ctatgtgggc taacagtttt catatttacg tgttttttta
      661 ttcttctccg gtttccgttt cagataccgg agtaaacaac agcgtataag cccagggacg
      721 tgcatgcttg aggtgtctca gccgtggcat acgtatcagc catccctcca cgctggtgga
      781 ctttttgagc attccagcct catgaaggat tctgccggca gtatccttgc tgagaggagt
      841 agaacctacg cccttcgcat tacgaatgcg agctaactcc aaaatgagta cgaacatgag
      901 tacaaaaaaa atatatcatt aaatgtagta taaatttcaa tcagatacag caaaaattac
      961 aattcaacgt ctaattccgc taatactact ctggcggtta ataacgagcc attatgtgag
     1021 ttgcacgtaa tggctttttt acgcctgcta cgcgtcttct ttcaattctg agttaccaaa
     1081 actcataatc agactcctga caatattaac aatgcagctt ttatgtgata acaatcacag
     1141 tgcattaacc gttcaagagt ttgtcatgaa aaaaacattt accttcagcc tgttagcaat
     1201 tgtctttgca agcctgttga gtgcttgtgt tccccaccat catcaccgcc acagcgatgg
     1261 ccctcgtggt cctgcgccct ccggtaagcc aatgccacct tcaaatggtg gaccaaatca
     1321 cggcagtcat ggtcgctatt aattagtaat tcatagcggg aaagtacata ctctcccgct
     1381 atccacggcg cttaaactgc cctgcatcaa tgccatgttg cttcattttc cgccacagcg
     1441 tagtgcggcc gattccaagt aaagccgaca tttcctgaat gcgaccgcct gtgacttggg
     1501 ctgcgttaat aattgcctct ttttcaactt ccgcaaatga cagactggtg gaaaggcggg
     1561 tggcgctgac atcatctgtc gcctgctcgg taaacagatg ttccggcaaa tcactgacgc
     1621 gaatgcgccc attatcacta ctcagagcaa gattctcgat gacgctgtaa agttcaaaat
     1681 cgttgccagg ccatgcacag gaaaccaggc gagcgagggc atcgtcatca attttcagcc
     1741 gcgtagagaa gcgtttttca aggctgcgta atttgttatt caccagcgcc ggaatgctgc
     1801 cacgccgcat acgcagtggc gggatggtaa tttcaaatgc atgcagcgcg taatacagct
     1861 ggcgactaaa acgattttgt tccaccagca ttgcgaggtc cgcggtcgtt gtggcaatca
     1921 ctttgacatc aatgggtatt aaacgccgcg catccagtcg cgtgataaca ccctgcttga
     1981 taacctgaag caaagcagac tgtaactcca ccgccagata ttcaatcttt tcaagaaaca
     2041 gcgtgccgcc gtgcgccagt tccagccgac tcagacggcc attttcatta tccgtgcgat
     2101 cgccaccaat aaattcttcc gccagcgccg catcaccata taactcacaa ttgacggcga
     2161 tataaggccc cgctgcacgc tcgctttcat tatgaattgc ctgacttagc agtgccttgc
     2221 ccacgccctc ttctccacaa agcaggacag gaaagctact gcgcgccgcc tggcgaccaa
     2281 aatgaatcaa gcggcgggtt tgcggatcgt cctgtggcat atgagcgaag gtatggctga
     2341 cttttcctaa ttgactggtc attaactgcc gcatctgttc cacaggatgg agcaataaaa
     2401 taaagctggt tccctgcgtt tctattatcg gtttaagggt tatcaccgca tcaataaact
     2461 gatgctgact ttcaaaggtt gcttctacgt gtttgagcgg atgtgcctgt tttattgctt
     2521 gttgcaatac ggcgggtaac gttaagagtt cagtgattgc ccttccctga cttgccgtcg
     2581 cgtcaaggcg caagactcgc gccgcctggg cgttgataaa ttgcaaatta ccctgctcgt
     2641 cccagctaat cacgccatca tccatacttt ctaacagggc attaagttga tttaaatgac
     2701 ggttagtttc agcgagcaaa ctgtccgtca gcagtaaatt tccgacctcg cgtgcgattg
     2761 ccaacgtcaa cggcaaatca gctgcggtag tttgctcaac cggacacgcc agcgctattg
     2821 ttcccgtcaa tcggcccttg ctgtcaaaca acggcgttgc gcaaaaggcc cagttccaga
     2881 gtgcctgttt gaaatgttga tcggccatcg ttttcacggc ctgaccagag atagccgcta
     2941 acgatagcgc acaagtacca ataattccct cggcgcaata cgtgccgtca ttgaatccca
     3001 gtacacttag ctgctgcaag gtttgcggat cgccattacg gctgagaatg caggcggttt
     3061 catcgaggat aagcaacgca cactctcgcg gtgccatata ttcccaggca tcttccagcg
     3121 cagcctgccc gagcgtcagc atcgctttct tacgccgata aatagaagca aatgtcacgc
     3181 cctgggcctg gtgtggtacg ttccatgtct cccgtttcat cagcttattg catctctccc
     3241 aggaggttgc aattaaggga gatatgcccc gaccatcgtt gttaaaagcg ccactcatat
     3301 cccgcatccc ttatgacaaa aggtgttccg gctcgcaatt ttaagtatta atacacgtaa
     3361 aagtttcaat atggaacact cattaaagca tatgtttcac tatgaaacat aatttgggct
     3421 aattttcttt tcccttgcct gatgcacaat ggattcatcg gcagtcagtg gtcgccgtgt
     3481 cgttgaacat catccatgcc ctaccgtaat tgctggagca aaataatgaa aaaattgatc
     3541 aatgatgtgc aagacgtact ggacgaacaa ctggcaggac tagcgaaagc gcatccatcg
     3601 ctgacactgc atcaggatcc ggtgtatgtc acccgagctg atgcccccgt tgcaggaaaa
     3661 gtcgccctgc tgtcgggtgg cggcagcgga cacgagccga tgcattgtgg ttatatcggt
     3721 caggggatgc tttcgggggc ctgtccgggc gaaattttca cctcaccgac gcccgataaa
     3781 atctttgaat gcgccatgca aattgatggc ggcgaaggtg tactgttgat tatcaaaaat
     3841 tacaccggcg atattcttaa cttcgaaaca gcaaccgagt tactgcacga tagcggcgta
     3901 aaagtgacca ctgtggtcat tgatgacgac gttgcagtaa aagacagtct ttataccgcc
     3961 gggcgacgcg gcgttgccaa caccgtatta attgaaaaac tcgtaggtgc agcggcggag
     4021 cgtggcgact cactggacgc ctgtgcggaa ctggggcgta agttgaataa tcaaggccac
     4081 tcaataggta tcgctctcgg tgcctgtacc gttcctgccg cgggcaaacc ttcttttacc
     4141 ctggcggata atgagatgga gtttggcgtc ggcattcatg gtgagccagg tattgaccgc
     4201 cgccccttct cttcccttga tcaaaccgtc gatgaaatgt tcgacaccct gctggaaaat
     4261 ggctcatacc atcgcacttt gcgtttatgg gattatcaac aaggcagctg gcaggaagaa
     4321 ccacaaacca aacaaccgct ccagtctggc gatcgggtga ttgcgctggt taacaatctt
     4381 ggcgcaactc cgctttctga gctgtacggc gtctataacc gcctgaccac acgttgccag
     4441 caagcgggat tgactatcga acgtaattta attggcgcgt actgcacctc actggatatg
     4501 accggtttct caatcacctt actgaaagtt gatgacgaaa cgctggcact ctgggacgcc
     4561 ccggtccaca ccccggccct taactggggt aaataaggag aaagcaatgt cactgagcag
     4621 aactcaaatt gttaactggc tcactcgttg tggcgatatt ttcagcaccg agagcgagta
     4681 tcttactgga ctggatcgcg agattggcga cgctgaccac gggctaaata tgaaccgagg
     4741 ctttggcaaa gtggtggaaa aactccctgc tatcgcagat aaagatatcg gtttcattct
     4801 caagaatacc ggcatgacgc tactttccag cgtcggaggt gccagtggtc cgctgttcgg
     4861 taccttcttt atccgcgccg cacagacaac ccaggcacgg caaagcctga cgctggaaga
     4921 gctttatcag atgttccgcg atggcgcgga cggcgtaatc agtcgcggga aagccgaacc
     4981 tggcgataaa accatgtgtg atgtgtgggt gccggtggtg gaatcgttac gtcagtcctg
     5041 cgagcaaaat ctctctgttc cggcggcgct cgacgctgcc agtagcatcg ccgaatccgc
     5101 tgcacaaagt acgattacga tgcaagcccg caaaggccgc gccagttatc tcggtgaacg
     5161 cagtattggt caccaggatc ccggcgcgac ctcggtgatg tttatgatgc aaatgttggc
     5221 gttagccgca aaagagtaag gaattggtga tggtaaacct ggtcatagtt tcacatagca
     5281 gccgactggg agaaggtgtc ggtgaattag cccgtcagat gttaatgagt gataattgta
     5341 aaatcgccat tgccgcggga attgacgatc cacaaaatcc cattggtacc gatgccgtca
     5401 aagtgatgga ggccatcgaa tctgttgccg atgccgacca tgtgctggtc atgatggata
     5461 tgggtagcgc attattgagt gctgaaactg cgctggaatt gctggctccc gagatcgccg
     5521 caaaagtacg tttgtgtgct gcgccgttgg tcgaaggtac actggcagca acggtcagcg
     5581 cggcctcggg ggcggatatc gacaaagtta tctttgacgc catgcatgcg ctggaagcca
     5641 aacgtgaaca actgggttta ccgtcctccg acactgaaat ctctgacaca tgtcctccgt
     5701 acgatgaaga agcccgttct ctggcggtgg tcataaaaaa ccgtaacggc ctgcatgtac
     5761 gtccggcctc ccggctggtt tataccttat cgacatttaa tgccgatatg ttgctggaga
     5821 aaaacggcaa atgcgttaca ccggagagta ttaaccagat tgcgttacta caagttcgct
     5881 ataacgatac gctgcgcctg attgcgaaag gaccagaagc tgaagaggca ctgatcgctt
     5941 tccgtcagtt ggctgaagat aactttggtg aaacggagga agttgctcca cctactctgc
     6001 gtcccgttcc gcctgtttcg ggtaaagcct tttattatca acctgtttta tgtacggtac
     6061 aggcaaaatc aaccctgacc gtggaagaag aacaagaacg attacgccag gccattgact
     6121 tcacgttatt agatctgatg acgttaacag cgaaagcaga aaccagcggg cttgacgata
     6181 ttgccgcaat cttttctggt caccatacac tgttagatga tccggaactg caggcggcgg
     6241 caagcgaact ccttcagcat gaacattgca cggcggaata tgcctggcag caagttctta
     6301 aagaacttag ccagcaatac caacagctgg atgatgaata tctacaggct cgctatatcg
     6361 atgtggacga tcttctgcat cgcaccctgg tccacctgac ccaaacgaaa gaagaactcc
     6421 cgcagtttaa ctcgccaact attctactgg cggagaacat ttatccctcc acagtactgc
     6481 aactggatcc agcggttgta aaaggtatct gccttagcgc cggaactccg ctatcccaca
     6541 gtgccctaat cgcccgtgaa ctgggaattg gctggatttg ccagcagggt gagaaactgt
     6601 atgcgataca accagaagaa acgctaacgc tggacgttaa aacgcaacgt ttcaaccgtc
     6661 agggttaaac caccgttcgg atggcatcat tctgatgtca tccggcaatt tactctgcac
     6721 tgatgttttt taactacctg ttatattttt caccaaatta tgatgatttt tcttcgctaa
     6781 tcgcgaaccc aacgtcgctg gctgacgaat aaacagatgt tattttatca ctctatttcg
     6841 ccgttattta tccctttaat tcccttttct aaaatgtctg tcagttcgca gaatgtgatt
     6901 tcgatcatgc agctagtgcg atcctgaact aaggttttct gatacttgaa taccgtttta
     6961 ttcggtttcg ccaaaggaga atgattgatg aaatcccccg caccttctcg cccgcaaaaa
     7021 atggcgttaa ttccagcctg catctttttg tgtttcgctg cgctatcggt gcaggcagaa
     7081 gaaacatcgg taacaccaca accgcctgat attttattag ggccgctgtt taatgatgtg
     7141 caaaacgcca aactttttcc ggaccaaaaa acctttgccg atgccgtgcc gaacagcgat
     7201 ccgctgatga tccttgctga ttatcggatg cagcaaaacc agagcggatt tgatctacgc
     7261 catttcgtta acgtcaattt caccctgccg aaagagggcg agaaatatgt tccgccagag
     7321 gggcaatcac tgcgcgaaca tattgacgga ctttggccgg tattaacgcg ttctaccgaa
     7381 aacaccgaaa aatgggattc tctattaccg ctgccaaagc cttatgtcgt gccaggcgga
     7441 cgttttcgcg aggtatatta ctgggacagt tacttcacca tgttaggact tgccgaaagc
     7501 ggtcactggg ataaagtcgc ggatatggtg gccaattttg ctcatgaaat agacacttac
     7561 ggtcatattc ccaacggcaa ccgcagttac tatttaagcc gctcgcaacc gcccttcttt
     7621 gccctgatgg tagagttact ggcgcagcat gaaggcgacg ccgcgttgaa acaatacctg
     7681 ccgcaaatgc aaaaagaata tgcttactgg atggacggtg ttgaaaacct gcaagccgga
     7741 caacaggaaa aacgcgttgt aaaacttcag gatggtaccc ttctcaaccg ctactgggac
     7801 gatcgcgata cgccacgacc agagtcatgg gtggaagata ttgccactgc caaaagcaat
     7861 ccgaatcgac ctgccactga aatttaccgc gacctgcgct ctgccgctgc gtctggctgg
     7921 gatttcagct cgcgctggat ggacaatccg cagcagttaa acaccttacg caccaccagc
     7981 atcgtaccgg tcgatctgaa cagcttgatg ttcaaaatgg aaaaaatcct cgcccgcgcc
     8041 agcaaagcta tcggagataa cgcgatggca aaccagtacg aaacgctggc aaatgcccgt
     8101 caaaaaggga tcgaaaaata cctgtggaac gatcaacaaa gctggtatgc cgattacgac
     8161 ctgaaaagtc ataaagtgcg caatcagtta accgcggccg ccctgttccc gctgtacgtc
     8221 aatgcggcag cgaaagatcg cgccagcaaa atggcgacgg cgacgaaaac acatctgctg
     8281 caaccaggcg gcctgaacac cacgtcggtg aaaagtgggc aacaatggga tgcgccaaac
     8341 ggctgggcgc cgttgcagtg ggtcgcgaca gaaggattac aaaactacgg gcaaaaagag
     8401 gtagcgatgg acattagctg gcacttcctg accaatgttc agcacaccta tgaccgggag
     8461 aaaaagctgg tggaaaaata tgatgtcagc accaccggaa cagggggcgg cggtggcgaa
     8521 tatccattac aggatggctt tggctggacc aatggcgtga cgctgaaaat gctggatttg
     8581 atctgcccga aagagcaacc gtgtgacaat gttccggcga cgcgtccact cagtgaatca
     8641 acaacacagc cgctaaaaca aaaagaggcg gaacctacgc cttaacttta ctgtatatcg
     8701 agcaatgcca ttacgtgcat aaaattggca ttgctctttc ttcatcacga aataccactc
     8761 tttctacggt ctatgccttt attttctttt attagagaag attttaattt tattttatca
     8821 acttgttaat catcacacct ctatttatat tttcccccac tccccattct ccctgacaat
     8881 tttcttgtgg aacaaagtgt tatttaagaa acaagcaaat cattctgtct ctttagacaa
     8941 attttgacat caaacatgat ctttttcgct atatgtgtaa gtatatagcg gttttaatta
     9001 tcaggatatt acttatgtca ctaaccagac ggaggtttac acagattctt gcgtcgacat
     9061 tgttcctgca tcatctgccg tcctttgcac aatcagtcaa attctgggcc tcactgacgc
     9121 ttcccgaagc ccaacacatt acacgcatcg tcagcgcagg cgcgcccgcc gatttactat
     9181 tgctggctgt cgcgccagaa aaaatggtcg gtttttcctc ttttgatttt gcccgtcagg
     9241 cattaattcc attgccagag cacattcgcc agttccccag gctgggacga ctcgccgggc
     9301 gcgccagcac actctcgctg gaagggctta tggcgttaca tcccgatttg gtcgttgatt
     9361 gcggcaatac ggatgaaacc tggatctccc aggcacggca ggttagcgaa cagacacaaa
     9421 taccctggtt attgcttaac gggaaactgg aacaatcagc agaacagtta acaacgcttg
     9481 gcaaaacgtt aggcgaagag caccgcgccg cagaacaagc caatctcgcc agccgcttcg
     9541 ttggtgaagc tcaggcattc gccacctcac ccgccgctaa tctcagcttt tatgctgcgc
     9601 gcggtcctcg agggctggaa acgggcttac agggttcgtt gcataccgag gcggcggaat
     9661 tattaggttt gcacaacgtc gcgcaaatag ccgatcgcca cggtctgaca caggtttcca
     9721 tggaaaatct cctgcgctgg cagccggata ttattctggt tcaggaggcc gttactgcag
     9781 attttattcg tcgtgatcct ctctggcagg gcgtgaaagc ggttgcggaa caacgcatct
     9841 tatttttaag tggcctgccc tttggctggc tggatgcccc gccgggaatc aaccgtcttc
     9901 tgggattacg cagacttcac gcctggctgg atcccgccat caatcgccag tttaaaagtg
     9961 acatgcagca ttacgcccaa ctgttctggc attgttcact cagtgacgcc gactatcaaa
    10021 aattggtggc gagctaatga gaaccgtaaa cggatgtatt ttgctgctgg cagctatcag
    10081 tatcactttt gccgccgtaa gtggggctta tcatctcgat atgcagcaac tgctggcgct
    10141 cattcttcgt caagaaaatg ttcctgtgca ggaacaaatt gtcttctggc aaatccgcgt
    10201 gccgcgtatt cttgctgcgc tgtttctggg cgcggcgctg gcaggggccg gaaccaccta
    10261 tcagggaatg ttccgtaatc ccttagtgtc accggatatt ttaggcgtct ccgccggtgc
    10321 cggacttggt gcctgcgcgg caatcctgtg gggattatcc attgtttaca tccagctgta
    10381 cgcattttgc ggcgggctga tggtggtcgc gggcgtctgg ttgattacgc gtcgggtgac
    10441 ccgccacgat ccgatcttaa ccctggtgct ggtaggcatt gcgttaggaa cgttgtgcgg
    10501 agcggggata tcgctaataa aaacgctggc cgatccttac acccagttac cgtcaattac
    10561 cttctggttg ctgggggggc tgtccaccgt gaccttacgc gatctctgct atgctgcacc
    10621 gatcattctc ataggctcct tgcccctgtt ttttctccgc tggcgcatga atttactcac
    10681 gctttccgac gacgaagccc gttcgctggg actgaacgtg acacgtctgc gctttggatt
    10741 gattgtctgc gccacactca tcaccgccag cacggtagca atagcaggca taattggttg
    10801 ggtcggcctg gtcgttccgc acattgcccg cttgttgacc ggtcataacc atcagcagct
    10861 gttgcccatg gcaatgtgta ctggcgcgat tctgctcctg cttaccgata cgctggcacg
    10921 cagcattgga acaacagaaa tcccacttgg cattctgacc gcttttgttg gtgcaccgtt
    10981 tttcctgttt ttgttgttac gcggaggtcg ccagtgactt tgcttgccgt ccgtcatgcg
    11041 tctctgggtt actcccgcca tccggtgcta cgcgacgtgt ccttcaccct gtcgcaagga
    11101 acaatttgtt gtctgttagg agccaatggt tgcggcaaaa ccacactcat gcgctccatt
    11161 cttggcgtta taccgttatt aaaaggcgag atcttactgg atagcctccc tgtgcagaca
    11221 ctcagccatc gccagcgcgc gcaggctatt gcctgggtgc cgcaggcgca cgacggcatt
    11281 tttgctttta gtgtgctgga tatggtgttg atgggcctgg cccccaccat aggcgctttt
    11341 tccgttcccg gtaagcaaga acgcctgaaa gcaacggagc aactggaaaa gctgggcatt
    11401 ttgcatctgg cgacacgacg ctggaatacg cttagcggcg gtgaacgtca gctggcttta
    11461 atcgcccgtg cactcgtcca gcaaccgcgc ttgttattac tggatgagcc tgcctccagc
    11521 ctcgatttcg gtcatcagat ccaacttctg gacacgctgg cgcagctcaa aaataacggc
    11581 atgacaatgt taatgtcgac tcatcatccg ctccatgcaa acgccattgc cgacagcatt
    11641 atccaggtag agccagatgg acgagtaaca caaggcttac cgaccgaaca gttaacaacg
    11701 aaaaaactgg ctgccctgta ccgggtttct gccgaccaga ttcaccatca cctctctgca
    11761 attaagcact aaggaaaaat catgctcatt gacgatattg attttgcaga cctttacctt
    11821 cagcaactca ggctggccca tcgcacagaa aaaacgccgg atcactggga tcaacgggcg
    11881 gaaaaaatgg cggaaaattg cgcctcgcct acggacagct acctgcaaca actgacctca
    11941 aaaattgacc tgcaaggcgc gcaaacctta ttcgatatgg gctgcggacc gggtaccgta
    12001 tcgctggcgc tggcggacaa actcacgacg atttatggcg ttgattacag tcaggggatg
    12061 ctgaacgttg ccgcccgtcg tgccgccgcg ctaaaggcag acaatgtcca ctggatccag
    12121 cgcgcctggg aagaggactg gagtgacctg ccacgctgcg atattgccgt ggcttcccgc
    12181 tccactctgg tggctgatat gcgccaggca atgagcaaac tgaataatca ggcacggctt
    12241 cgcgtctata cgactcatct ggtcagcacc tcgttcgtct ctccagccat tcagcgggcg
    12301 gctggtcggg aagtgatcga attacccaac tatatctttg cactcaacgt cctgtatcag
    12361 atgggaattt atgctcacgt tgattttatc cgcggacaaa attgccaaca ggataacagc
    12421 acctgggaac gttttgagca gaacgtcagc tggagtctgg gcgcgcttaa cgacgatgag
    12481 cgtgagcggt tatatcgctg gtatcaacaa caagatgctc gtgccctcgc ccctgccagc
    12541 cgcgactggg cgctcatctg gtgggatagc gtaccgcagg agacactgcg atgattttcc
    12601 tttctcaggc acaaatcgat gcgttattgc tggaagatat ccagggcggt gacctgacca
    12661 cgcgagcatt aaatattgga caccagcatg gctatataga gttttttctc cgtcagggcg
    12721 gctgcatcag cggcatttct gtcgcgtgta agatgttaac tacgctggga ttaactattg
    12781 atgacgcggt cagcgacggt tcacaagcga acgcgggtca gcggctaatc cgtgcgcaag
    12841 gtaatgccgc agcacttcat cagggatgga aggcagtcca gaatgtgctg gagtggagtt
    12901 gcggtgtttc tgattatctc gctcaaatgc tggcgttact tcgtgaacgt taccctgatg
    12961 gcaatatcgc ctgcacccga aaagcaattc cgggcacccg cttactggcc tcgcaggcaa
    13021 ttctggctgc cggaggactg attcatcgtg ccggatgtgc ggaaaccata ttattgtttg
    13081 ccaaccaccg ccattttctt catgacaatc aggactggtc aggcgcaatc aatcagttac
    13141 gtcgccacgc acccgagaag aaaatagttg ttgaagccga cacgccgaaa gaggcaatcg
    13201 ccgcgttacg cgcgcaacca gacgtacttc agctcgacaa atttagtccg caacaggcaa
    13261 ctgaaattgc gcaaatagca ccgtcgctgg ctccccactg cacgctggct ctgaccggcg
    13321 gaattaatct gacaacactc aaaaattacc tcgactgcgg cattcgcctt tttattacct
    13381 ccgcgcctta ttacgcgaca ccagctgaca ttaaagtcag tctgcaaccc gcagcctcta
    13441 tttaattctt tgttaaacgg aatttattct atgagactca aaaaacgtta tctctgcaca
    13501 gcattatcac ttgcctttac ccagcaggcc gtagcggctc aggagagtga cacgctgacc
    13561 gtatggtcca gtccggtatc atcaacgacg accaccgttc tcgatcaacc caccatgaag
    13621 gccctggata aacagaatgt cgctcaggca ttaagtgtcg tccccggcgt ggtgctgcaa
    13681 aagtcaggta gccgcaacga agaacaggtc aaagttcgtg gctttgatag tcgtcaggtg
    13741 ccggtctatt tcgacggtgt gcccatttat gttccctatg acggcaacct cgatctggcg
    13801 cggattctga ccaacaattt gggggcagtt gaagtttcca aagggtattc gtcgctgctt
    13861 caggggccta atcagatggg cggagccatt aatatcacca cccagaagcc aacaaaacct
    13921 ctggaagcaa gtctgggata tcgccaggga tggagccgta gccaggacaa tgcctacgat
    13981 atgcatgctt catttgccgc cagcagcgat ctggggtatt tgcaagtcag cggtagccag
    14041 ctaaagcagg attttctcgg cctgccgcat ggtgtaaata atgatattgc aggcaaacac
    14101 ggcaagatga ttaattcatc ggctgatgat aaacgcggca ttgtgaagct cggttttaca
    14161 ccacgcgaaa acgatgaata cacattgact tacattaagc aggatggtga aaaagataac
    14221 ccgccataca gtggaaatag tggtcagaaa tcacgctact ggcagtggcc agagtatgac
    14281 aaagaaagtt tttattatca gggaacgacc caactaaacg atcgttttac cctgaaaagt
    14341 cggctgtatc gcgacacctt tgaaaatacg ctaatgatgt acaactcgct ggctgatttg
    14401 aaaaataaaa aaggcagcta cagccattat tccgattaca gcgacggtgc cgggttacaa
    14461 ctggcagccg atgtgcgtga aaacgatctg ctgtcgtttg ccgttaactg gaaagatgac
    14521 gtacaccggg aaaaaggtgc gccgcacgcc gcttacgatc gctatgaaga tcgtacctgg
    14581 tcgctcgcca gtgaatatca atgggctgct gccgataatg tcgatgtcgt ggctggaatc
    14641 agctatgact ggcgcgatag cgtagaagcg aaaaaacatg agaaagatgg cagtatcacc
    14701 cattatgacg acaacaatca gtcagctttt aactggcagg tgatggggaa ataccacttt
    14761 gccaatgaag acacgctggc gctttcgtac tatgaccgca cacgctttcc gacgctgaaa
    14821 gaacgctata ccacgtccaa acctgcgtat aaccagatag cgattgttaa cccgcagctc
    14881 aagccggaac gcgcgcgcgg ggtggattta acctggaatg gtgccttcac gcacgactgg
    14941 ggatttgagg tcagcgttta ctataaccgg gtgagtgatg ccatcctctc gcacaatatc
    15001 gatgccgata ccattcaaaa tcagaacagc ggcacggtgg attacagcgg tctggatgcc
    15061 ggtattaagg ggaaaatcag caatatactg gatgtaggat tgagctacgc cctgatccac
    15121 gctgatgcca aacgcaaaga catcggcaag ataaccgatc tgccaacgca gacaatgacc
    15181 gcatggatga ctctcaaacc gtgggagccg ttaagcgtaa cgctgtcgga agaggcgcgt
    15241 tcctccagct acagcaacag tgacggttca caaaaagccg ccggttttgc ggtgactcac
    15301 attcgagccg attacacctt aggtcatggc ttcagcgtta atgcgtcggt caataacctg
    15361 tttgatacca aatatgccta cagtgaaggg tttattgaag aaggtcgcaa tttctgggca
    15421 ggtatcgagt atacgttctg atgtgaaagc ggatagcggc atctgtatcg ctatccgcct
    15481 tatgaaaatc ttattctctt cgcaggaggc ggaatacgcc cagcaccagg atagcgccca
    15541 ccaccgccac caggaagctg tgcaaattaa aaccgctgat ggagccgcca atgccaaaca
    15601 tggtcgccag ccagccgccg accaccgcac cgactatccc aagaatacag gtcaggaaaa
    15661 atccaccacc atctcgcccc ggcatgatta gcttggcgat aatgccggct atcaggccaa
    15721 aaataatcca ggcaataatt cccatgttca ggccctcgtt tcgatgaatc ggacgcaaga
    15781 aatgcttacg tcaacgctct aagtataggc aagggcggga tcgatgctgg gcatatgtcg
    15841 gctgatttaa gaacaacatg taaaaaatat tcgcgcattt gtattaagtt ttgttaactg
    15901 cgaccgataa accaaagaca gtttgtcagt caggagtttt tccgcgtgag tcattaccat
    15961 gagcagttcc tgaaacaaaa tccgttagcc gtcctgggcg tgttacgcga tttgaacaaa
    16021 gccgcaattc ctttgcgtat cagctggaat ggcgggcagc tgatcagcaa aatactggca
    16081 ataactccgg ataaactggt gctggatttc ggcagccagg ccgaagacaa catcgccgtg
    16141 ctaaaggcgc agcacattac cattaccgcc gaaactcagg gtgcgaaagt cgagtttact
    16201 gttgaacaac tacagcagag tgaatacttg cagcttccgg catttattac cgtaccgcct
    16261 cccaccttat ggtttgtaca acgacgccga tatttccgca tcaccgcccc actccatccg
    16321 ccttattttt gccagaccaa actggcggat aacagtacgt tacgtttccg cctgtatgat
    16381 ttgtcgttag gcggcatggg cgcattactg gaaacagcaa agcctgccga attacacgaa
    16441 ggcatgcgct tcgctcagat tgaagtcaac atggggcaat ggggtgtttt tcactttgac
    16501 gcccagttaa tctccatcag cgagcgcaaa gtgattgatg gcaaaaatga aaccatcacc
    16561 actccccgtc tgagcttccg ttttcttaac gtcagcccga cggtggagcg gcaattacag
    16621 cggattattt tctctctcga gcgagaagcc cggaaaaaag cggacaatgt gcgtgactga
    16681 tttacatcgc gtccagtgcc tgctcaagtt tgtagatata gcgcggagcc tgcggcgcag
    16741 gatgatttcg cgctacgtga tcgaggaact catcagcatc cagatcgttg attttgctga
    16801 tcgccttttt ccgatctgac gagaaagtcc gtagcagcgc acctgccccg ttagcgtatg
    16861 acaccaccag cgcatattgc agtaccttcg gatcttcaat gcctgccagc gggccggttt
    16921 ccagaatatt caggtaagcc gctcccattg aaatattacg ctccggattt ttcagctcgc
    16981 tggtcgtcgg ctcaccgctc cagcccatac gacgatatac atcacgtccg gaggttgaag
    17041 cttttatctg catcaaacca atggcattcg atttactcac cgcgttcgga ttaccacccg
    17101 attcgatagc gataatcgcc gtgatcaatt gtggatcgac gccccaggct gcaccggctt
    17161 tctggcttat tggcatccac tgcatcgcac gttgcaccgg aactttcgcg ttccacggcg
    17221 ggttcgtata gtcatgcttt gatgaacaac ccgctaataa cacaatcaaa aaggcaaacc
    17281 atctcaattt cacttcttct atccttatag cctggaatcg ccgttgaggt gacaacggca
    17341 cacctaagcg gcatgatata catttcgttt ctgttgtcag caaggaattg ccatgtctct
    17401 gtttcactta attgccccat cgggttactg cattaaacag cacgccgcgc tgcgtggtat
    17461 ccagcgcctt accgacgcgg ggcatcaggt caataacgtc gaggttattg cccgtcgttg
    17521 tgagcgtttt gcgggtacgg aaacggagcg tctggaagat ctcaattctc ttgccagact
    17581 gactaccccc aacaccatcg tgctggctgt acgcggcggt tacggtgcca gtcgtttact
    17641 ggcagatatt gactggcagg cactggtggc tcgccaacaa catgacccgt tactcatttg
    17701 cggacatagc gattttaccg ccattcagtg cggtcttctg gcgcaaggca atgtcatcac
    17761 ctttagcggc cccatgctgg tagcaaactt tggcgcggat gaactaaatg cctttaccga
    17821 gcaccacttc tggctggcgt tacgcaataa aacgttcacc attgaatggc aaggggaagg
    17881 cccgacatgt cagaccgaag gcacgctgtg gggaggcaat cttgcgatgc tgatttcact
    17941 gattggtaca ccgtggatgc caaaaattga gaacggtatt ctggtgctgg aagatattaa
    18001 cgagcaccct ttccgcgtcg aacgcatgct gttgcagctc tatcatgctg gaattttgcc
    18061 acgtcagaag gcgattattc tcggtagctt tagcggcagc acacctaatg attatgacgc
    18121 aggttacaac ctggagtcag tgtacgcgtt tttgcgttcc cgcctgtcga ttccactcat
    18181 taccggcctc gattttggtc atgaacaacg cacggttacg ctgccgttgg gcgcacatgc
    18241 cattctgaat aacaccgagg aaggcactca gttgacgatt agcggtcatc ctgttcttaa
    18301 aatgtaaaaa aatcacgctt cagggctaag taaaacgctg tctctgccgc taatatggta
    18361 gggtttatat cagagacagc gtaatcagga gtaaccgacc gttggatgcc acaacaataa
    18421 ttagcctttt catcttagga tccatccttg tcaccagcag tatattactt agttcatttt
    18481 cttcccgtct tggcattcct attctggtta tttttctggc gatcggcatg ttggcggggg
    18541 ttgatggcgt cggcggtatc ccgtttgata attacccctt cgcctacatg gtaagtaacc
    18601 tggcgctggc gattattttg ctcgacggcg ggatgcgcac tcaggccagt tcctttcgtg
    18661 tggcgttagg accggcactg tcgctggcga cgctgggcgt acttatcacc tctggtttaa
    18721 ccggcatgat ggcggcgtgg ctgtttaatc ttgatttgat tgaaggatta ttaatcggcg
    18781 ctatcgtcgg ctccaccgat gctgcagcgg tcttttctct gctgggtggt aaggggctta
    18841 acgaacgtgt tggctcgacg ctggaaattg aatccggcag taatgatcca atggcggtct
    18901 ttctgacgat tactctgatt gcgatgatcc agcagcatga aagcagtgtc agctggatgt
    18961 tcgtggtcga tattctgcag caatttggcc tcgggattgt catcgggctt ggcggtggtt
    19021 atttactgct gcaaatgatt aatcgcatcg ccctgcccgc cggattatat ccattgctgg
    19081 cattaagcgg cggtatttta atttttgctt taaccacggc gctggaaggc agcggtattc
    19141 tggctgttta tctgtgcggt tttctgctgg gtaatcggcc gattcgcaac cgctacggca
    19201 tcctgcaaaa tttcgacggc ctcgcctggc tggcgcaaat cgccatgttc ctggtgctgg
    19261 ggctattggt taacccaagc gatctgctgc ctattgccat tccggcgctc attttgtccg
    19321 catggatgat tttcttcgcc cgtcctcttt cggtatttgc cggattgcta ccgttccgtg
    19381 gcttcaatct gcgtgagcgc gtgtttatca gctgggtagg attacgcggc gcggtgccga
    19441 ttattctggc tgtgttcccg atgatggcgg ggctggagaa tgcgcgactg ttctttaatg
    19501 tcgccttctt tgtggttctg gtttcactgc tattgcaggg aacatcactc tcgtgggcgg
    19561 cgaaaaaagc caaagtggtc gttccgccag tgggacgtcc ggtgtcacgc gttggcctgg
    19621 atattcatcc ggaaaatccg tgggagcagt ttgtttatca attgagtgcc gataaatggt
    19681 gcgtgggcgc ggcactgcgt gatttgcata tgccaaaaga gacgcgtatt gcggcactgt
    19741 ttcgtgataa ccagttgctt catcccaccg gcagcacccg actgcgcgaa ggcgatgtgt
    19801 tgtgtgtaat tggtcgggaa cgcgatctcc cggcgctcgg taaactgttc agccagtcgc
    19861 cgccggtcgc gctggatcaa cgcttctttg gtgacttcat tctcgaagcc agcgccaaat
    19921 atgctgatgt ggcgctgata tatggtctgg aagacgggcg agaatatcgc gataagcagc
    19981 aaacgctggg tgaaatcgtc cagcagttgt taggcgcggc accggttgtc ggtgaccagg
    20041 tagagtttgc cgggatgatc tggacggtgg ccgagaaaga agataatgaa gtgttgaaga
    20101 ttggtgttcg ggtagcggag gaagaagccg aatcttaagt ttaatgtgtt tcgtaacgct
    20161 ggatacgacg ctggtcgcat ccagcgataa caagttacac cgtcacaacc gggacgcgta
    20221 acgccagcgc gcacatcaac tcatagccta ccgttccggc agcggcggcg acatcatcaa
    20281 ttttgatctc cttgccccac agctcaactg gcgtaccaat acccgcttgc gggcaaggcg
    20341 ttaaatcgac cgccagcata tccatcgaga ctgtccccac cgtcatggtg cgaacgccgt
    20401 ccactaaaac aggggtaccg gtaggcgcgt ggcgcggata accgtcggcg tatcctgcgg
    20461 cgacaatgcc gattcgctgt tcatcgcgcg cagtatagcg accgccgtag cccacacgct
    20521 cgcccgcttt tagcgtctgg acaccaataa tctcactgct tagcgtcatc accggacgta
    20581 atccggtatt ggcgatatca cgccactgac cggacggcga agcaccatac aaaataatgc
    20641 caggccgaac ccagtcaaaa tgcgcttcct ggtgccacag agtcgccgcc gaattagaca
    20701 acgaacgccg acactccagc ccttccgccg cctgctcaat acgcgccatc gcgctggaaa
    20761 ttccatcagg atgttccgct tcggcaaaat gcgacatcag ggtcatttcg ccaacattcg
    20821 ccatcgcccg caactgctgc cagacggtaa gcacgcgatc gggctggaag cccaaccgat
    20881 tcatcccact gttcacttta agataaatat ccaacggtgc ttttagccgc gcattttgca
    20941 gtgctttgag ctgccagttg ctgtgtacgc aggtggtcag gcggtgctgg tcataaatct
    21001 ccagatcctg agcatggaaa aatccttcca gcatcaggat cggtcctttc cagccgcgct
    21061 cacgtaacgt tattgcctct tccaggttaa gcaatgcaaa gccatcggta gccccgagcg
    21121 cgctccagat acgctcaata ccgtgcccgt aagcgttcgc ttttaccacc gaccagacgc
    21181 gcgcgtgcgg cgcggcctgg cggacaatgg acagattctg ttttaatgcc tgcagatcga
    21241 ggctggcctg tatcggacgg gtcatctcgt ttccttagct gtgtgcgcca tgtaaatggc
    21301 ccgggcgtga tggcgtaaat ccacggctgt agcgcgctac gcttagagct tcatacggga
    21361 tcgctggcgt gcgccccgag agcagatcgc ttaacaactg accggaaccg caagccatcg
    21421 tccagccgag cgtgccgtga ccggtattca accacagatt tttaaagcgt gtacgcccga
    21481 caaccggcgt gccgtctggc gtcatcgggc gcaggccagt ccagaaagcc gcctgatcaa
    21541 catgaccgcc gcgtggatag agatcgcgaa ccaccatctc cagcgtttca cgacgcggtt
    21601 gcaacagctc ggtgttaaaa ccaacaattt ccgccattcc gccgacacga atgcggttat
    21661 cgaaacgggt aatggcgatt ttgtaggttt catcaagaat agtggatacc ggcgcaccat
    21721 cttcctgcgc aattggaatg gtcagcgagt agcctttcag cggatacacc ggaatatcaa
    21781 caatgccttt gagcatcgcc gtcgagtaag aaccaaacgc catcacatac gcatcggcct
    21841 taatcacttc atcaccacac ttcacgccgt agatttgctc gccgtcgcaa agcagttggt
    21901 caacgggcgt attaaagcgg aatttaaccc ccgcctgctc cgccatccgc gccagattct
    21961 gggtaaacag ctggcagtct ccggtttcat cattgggcag ttgcaggccg cccgtcagtt
    22021 tgtgcgctac ttctgccaac gcgggctcca cttccgccag gcggctggat tccagcagct
    22081 gatacggtac gccagcatct tccagcacgg cgatatcgcg ggtcgcgttt tcatactgtt
    22141 gttcggtacg gaacagttgc agcgtcccac cctgacgccc ttcatactga atattggttt
    22201 cggcgcgcaa tgctttcagg caatcacggc tgtattccgc cagacgtacc atccgccctt
    22261 tgttttccat gtagtggctg gtgtcgcagt tacgtaacat ttgccacatc catttcaact
    22321 ggaactgcgt accgtcgaga cgaaccgcca gcggcgcatg gcgctggaac atccatttaa
    22381 tcgcttttaa aggcacacct ggtgccgccc acggtgcagc atatccgggg gagatttgcc
    22441 cggcattcgc ggcactggtt tccagggcgg cccccggctc ccgatcaatg acggtgacct
    22501 catgtcctgc ctgatttaag taccaggcgc tggcaacgcc taccacacca cttcccagta
    22561 tgacaactcg catagccact ccgataacgg tagatacagt aaaagaataa taatctaatt
    22621 acatcttgat aactcagttg aaaatattat tcaacatacg gcttttttat ggtgagctgg
    22681 ctcacatctc cctgactctg cggcaatatg gcgtctttag tatctcctgc tgaacgccct
    22741 ttttatccag cataaaattc cgttcagaag cggattagtg gcactctgat aataagaaat
    22801 cgcaaagaaa aaaattctcc ggcgacgcgg tttttaacag gtgttctatg cttgaaatga
    22861 ggtgctccac acagagagcg ccgacaacaa tgaggtgcgc gtatggcgac gatcgattct
    22921 atgaataagg acaccacacg tttgagcgat ggacccgact ggacgttcga cctgctggat
    22981 gtttatctgg cagagataga ccgggtggcg aaactctacc ggctggatac ctacccgcac
    23041 cagattgaag tgataacctc agaacagatg atggatgctt actccagcgt cggcatgcca
    23101 attaactatc cgcactggtc attcggtaaa aagtttatcg agactgaacg gctgtataag
    23161 cacggtcagc aaggactggc ctatgaaatc gtcattaact ctaacccgtg tatcgcttac
    23221 ctgatggaag agaacaccat taccatgcaa gcgttggtga tggctcatgc ctgctatggg
    23281 cataactctt tcttcaaaaa caattactta ttccgtagct ggaccgacgc cagttcgatt
    23341 gtcgattatc tgatttttgc ccgtaaatat attaccgagt gcgaagaacg ttatggcgtt
    23401 gatgaagtag aacggcttct ggactcgtgc cacgcgctga tgaactacgg cgtggaccgg
    23461 tacaaacgcc cgcaaaaaat ctcgctgcaa gaagagaaag cccggcagaa gagtcgcgaa
    23521 gagtatctgc aaagtcaggt caatatgctc tggcgtaccc tgccgaagcg cgaggaagag
    23581 aaaacggttg ctgaagcgcg ccgctatccg tccgaaccac aagaaaacct gctctatttt
    23641 atggagaaaa atgcgccact gctggaatca tggcagcgtg aaatcctgcg tattgtgcgt
    23701 aaggtgagcc agtattttta tccgcaaaaa cagactcagg tgatgaacga aggctgggcg
    23761 accttctggc actacaccat ccttaaccat ctgtatgatg aagggaaagt aacggaacgt
    23821 tttatgctgg agtttttgca cagccacacc aatgtggtct tccagccgcc ctataacagc
    23881 ccgtggtaca gcggcatcaa cccatatgcc ctcgggttcg ccatgttcca ggatattaaa
    23941 cggatttgtc agtcgccgac ggaagaagac aaatactggt tcccggatat cgccggttcc
    24001 gactggctgg aaacgctgca tttcgcgatg cgtgatttca aagatgagag ttttatcagc
    24061 cagttcctgt caccgaaagt gatgcgtgat ttccgcttct tcaccgtact ggatgatgat
    24121 cgacataatt atctggagat ttccgctatt cataatgaag aaggttatcg ggaaatccgt
    24181 aaccggttat cgtcgcaata taacttaagt aatctggagc cgaatattca gatctggaac
    24241 gtggatttgc gcggtgaccg ttcgctgacg ctgcgttaca ttccacataa tcgcgcaccg
    24301 ttggatcggg ggcgcaaaga agtgctgaag catgtgcatc gcctgtgggg atttgatgtg
    24361 atgctggaac agcaaaacga agacggcagc atcgagttgc tggaacgttg cccgccgaga
    24421 atgggaaatc tgtaaaaaca acgaaaaacc cctcgtttga ggggtttgct ttttaaacgg
    24481 aagggattat cgtccctgaa tggctaaatc acccggcaga tttttctgca tccggtgcca
    24541 aatctcgcca ctctcatgcc catagcgacg cactgtttca tatacctgat cgtgtgcgcc
    24601 ttcactgcac aacgccgaca gtttgtgata gaagcccagc gccagactgc gcgcttccgg
    24661 attggcgaaa tagtgacgac caatgcgcgt atacagccct ttcatcccgt taaggatcag
    24721 accgtaaatc gggttgccgg aagcaaacgc caggccgcgg aaaatgttgt aatccagctc
    24781 ggcaaaggcg tcggcgtgat cggccacttc attagcggtt gccagcactt cctgcgcttt
    24841 atcgggatgt tgacgaaacg cggtgcgaat aaaaatagtt gaaatattgg tacgcaccga
    24901 cagcaaatta tcaataagct gcggcacact ttcgtggtcc agtcgcgcca gtgtttcaag
    24961 gatatttaaa ccagaggttt cccagaaatt attcaccttc gtcggcttgc cgtgttgaat
    25021 ggtcaaccag ccatctcgtg ccagacgttg taacacttca cgtaacgtag tacgcgttac
    25081 gccaattaat tctgaaagtt cacgttctgc gggcaaaata gtcccgggag ggaagcggtt
    25141 attccagata ctttcaataa tgtactcttc cgcgaaaccc gccgggcttt gcgccttaat
    25201 gaccatagtg agatttccat aacacagcaa aacaaagttg gactcatcat accagagggc
    25261 taactacgct gatagaagac aaaaagaaga aaaaagggat caaggcttca ttttctgcat
    25321 ctctttcccc ttgactatca agacttgcct cactcctgtc tgaccgttaa gctttgcgtt
    25381 taaacataaa aacatcattg attatttcta aggtaaggga aaccatcatg gagatctcct
    25441 ggggccgcgc actatggcgc aattttttgg gccagtcccc cgactggtac aaactcgccc
    25501 tcatcatttt cttaatcgta aatccgttaa ttttcctcat cagccctttc gtcgctggct
    25561 ggttgctggt agcggaattt attttcactc tggcgatggc cctgaaatgc tacccgctgc
    25621 tccccggtgg tctgttggct atcgaagcgg tattcatcgg catgaccagc gcggaacatg
    25681 ttcgtgaaga agtggcggca aatcttgaag tcttgctgtt actgatgttt atggtggcgg
    25741 gtatctattt tatgaaacag ctgttgttgt tcatatttac ccgtttgctg ttaagcattc
    25801 gctccaaaat gctgctgtcg ctctcttttt gcgtggcggc ggcgctcctc tccgcgttcc
    25861 tcgatgcctt aaccgtcgtg gcggtggtga tcagcgttgc agtcggtttt tatggtattt
    25921 atcaccgcgt agcctcttcc cgtactgaag ataccgacct gcaagacgat agtcatatcg
    25981 acaagcatta caaagtggtt ctggaacagt tccgtggctt tctgcgtagt ctgatgatgc
    26041 atgccggtgt cggcaccgca ttaggcggcg tgatgaccat ggtgggcgaa ccacagaacc
    26101 tgatcatcgc taaagcggct ggctggcatt ttggcgattt cttcctgcgc atgtcgccgg
    26161 tgaccgtccc ggttctgatt tgtggcctgt taacctgcct gctggtagag aagctgcgtt
    26221 ggtttggcta cggtgaaacg ctgccggaga aagtccgcga agtactgcaa cagtttgacg
    26281 atcaaagccg caaccagcgt acccgtcagg ataaaatccg tctgattgtc caggcgatta
    26341 tcggcgtctg gctggtgact gcgctggcac tgcatctggc ggaagttggt ttgattggtt
    26401 tgtcagtcat tattctggcg acatcattga ccggtgttac cgatgaacat gctatcggta
    26461 aagccttcac cgaatctctg ccattcaccg cactgttgac ggtgtttttc tcagtagtcg
    26521 cggtgattat cgaccaacaa ctgttttcgc cgattattca gtttgtgttg caggcatctg
    26581 aacatgctca gctgtcgttg ttctatattt tcaacggtct gctgtcatcc atttcggata
    26641 acgtcttcgt ggggacgatt tatatcaacg aagcgaaagc ggcaatggaa agtggcgcta
    26701 tcacgttgaa gcaatatgag ctgctggcgg tcgccattaa taccggtacc aatctgccct
    26761 ccgtcgctac gccgaacggt caggctgcgt tcctgttcct gctgacctct gcactcgcgc
    26821 cattgattcg tctctcttat ggccgcatgg tgtggatggc cctgccttac accctcgtac
    26881 tgacggttgc cgggttactc tgcgtcgagt ttacgcttgc tcctgtaacc gaatggttta
    26941 tgcaaatggg ctggatagca acgctttgat aacaacttac cgggcatata aatgcccggt
    27001 ttgccttttc gcccgataat tgtccaattg cgtcctattt ttgctgcctc ctggtggcgc
    27061 agcgaatgaa ttggtttaaa ctgcgcactc tatgcatatt gcagggaaat gattatgttg
    27121 cgatttttga accaatgttc acaaggccgg ggcgcatggc tgttgatggc gtttactgct
    27181 ctggcactgg aactgacggc gctgtggttc cagcatgtga tgttactgaa accttgcgtg
    27241 ctctgtattt atgaacgctg cgcgttattc ggcgttctgg gtgctgcgct gattggcgcg
    27301 atcgccccga aaactccgct gcgttatgta gcgatggtta tctggttgta tagtgcgttc
    27361 cgcggtgtgc agttaactta cgagcacacc atgcttcagc tctatccttc gccgtttgcg
    27421 acctgtgatt ttatggctcg tttcccggaa tggctgccgc tggataaatg ggtgccgcaa
    27481 gtgtttgtcg cctctggcga ttgcgccgag cgtcagtggg aatttttagg tctggaaatg
    27541 ccgcagtggc tgctcggtat ttttatcgct tacctgattg tcgcggtgct ggtggtgatt
    27601 tcccagccgt ttaaagcgaa aaaacgtgac ctgttcggtc gctaatccat tcggcgctcc
    27661 tgcgggagcg ctttttcctg ccgctatgtt tatttgaccc gcagtaaatc agaacttcgc
    27721 gttgtataac atggtgaaag catggcacgc ttcatctgcc attgttgctg gatcccctgc
    27781 ccggcaaaat agagtgttcc tctgccctct ttagcattca gcgtatccat taccgccatc
    27841 aattgctcac tcccggggcg tggtgcgttg tcatcgaata aattgagctg cgcgactccc
    27901 tgactgaaga aatcccccag catcacgccc gctttttggt agcgatggcc cgcttgccag
    27961 atggcatcca gagatcgcgt agcggcgtta atgatatccc tgctgtcctg agtgggcgtc
    28021 agcagtttta ccgatgcgct attgccgtaa taaggttcat tgaacgcaaa tggtgacgtc
    28081 ttaataaacg tggagataaa ccgacaatat tgatgctcgc tgcgaagttt ttccgccgcc
    28141 cgggcagcgt aactacaaat ggcctgccgc atcgacggat aatccgtgat gcgttcacca
    28201 aacgagcggg aacagataat ttcctgcttc gtcggtgcaa actcttccag ttgcaaacag
    28261 ggttcaccgc gcagttcacg caccgttctt tcgagcacga cattaaaatg tttacggata
    28321 aaccggatat ctgaatctgc caaatctaga acggttttga tccccatcgc gtccagtttt
    28381 ttgctgatcc gccgtccaat cccccagact tcatccacgg ggagagcaga cattaattta
    28441 cgctggcgtt ccagatttga taaatccacc accccacccg tctgccgctg ccattttttt
    28501 gccgcatgat tggcaagctt agccagcgtt ttggtctggg cgatccccac accaacagta
    28561 agatgggtac gttgtagcac cgttgcgcga atttctctgc caaaatcagt cagatcgcga
    28621 caattatgca cacctgtcag atcgcagaat gcctcatcaa tactgtaaat ctcgacgcgg
    28681 ggcgatagtt cttccagcgt cgacatcacc cgattactca tgtctgcgta aagctcataa
    28741 ttgctgctaa agcaaaccac gccacagcga cgaaacagat ctttttgttt gaaccaggga
    28801 tcgcccattt taacgcccag cgcctttgcc tcagcgtttc gggcgataac gcaaccgtca
    28861 ttattcgata gcacaaccac cggtttaccc cataaatcag ggcgaaacac cgtctcacag
    28921 ctggcataaa acgcgtttac atcacagagg gcaaacatca gcgcatcgcc ttaacgacgt
    28981 ggatcaccac accaaagaca tccagcgtat cttcgctact gatggtaatg ggcgagtacg
    29041 cactgttcat aggaataagc tgtaccgtcg ggcgtagttg caattttttc accgtaaact
    29101 cgccgtcaac agcagcgatg ataatatcac catggctggc ggtaatagcg ctatcgacaa
    29161 tcagtaaatc accgtcacta atcccaccat caatcataga atcaccactt gctttgacga
    29221 aataagtcgc gctgggatgc tggatcaaca gttgattcag atcgatgcgc tgttcaacgt
    29281 aatctgcggc cggtgaagga aagccacact gaacaagatc gctaaatagc ggaaaagtca
    29341 caatttcgcg gagatccgca ggcttgataa acaacataat aatctgcctg aagttatact
    29401 gtttttatat acagtagtct gttcttgtca gcagatcaat actgattcag gctatcaata
    29461 tttgtcgctg catagactgc tgatttttcg ttctcttatc ctgtgctcac gcggccttct
    29521 ggcgacagcg tccatccagc agaaaggaaa aatatcacct ggtttaaaat agaatcgaag
    29581 cattcgccca gaaaggcatt ctcattaagg tactggatga cggcatcaag aaactgtgtt
    29641 ctattgctgc gggcgtagtt gaagggaaac tgattccaga attgaagaac aagttaaaat
    29701 ctgtgcagag tttctttacc accctgtcta acacggttaa acaagcgaat aaagatatcg
    29761 atgccgccaa attgaaatta accaccgaaa tagccgccat cggggagata aaaacggaaa
    29821 ctgaaacagc cagattctac gttgattatg atgatttaat gctttcttta ctaaaagaag
    29881 cggcccaaaa aatgattaac acctgtaatg agtatcagaa aagacacggt aagaagacac
    29941 tctttgagat acctgaagtc tgataagcga ttattctctc tatgtactca aggtataaaa
    30001 tttatcacat ttaaaaatac agacgttttt taaagattga gagttacctg ttgataataa
    30061 agtatcgggt aactctcatt atgacagagc gctttcaaaa acagggctac gaaatggcga
    30121 gcatccagac gtatattaag aaagccccca tcaacatcta ttaaatttat cactgcgccc
    30181 agtcaggttt atttaagata tgatcctgcc agtcaatcac ttctgattct ttcactgcga
    30241 tatgacgcac agagatacgt tcaccatgca ttgccgcttt cgaaccagta agtagcggat
    30301 gccacgcagg taaaccttta ccttccgcca gcaaacgata agcgcaggtc attggcagcc
    30361 attcgaatgt tggcagattt tcacgggtta atttaatgca gtcgggttca aactcgaaac
    30421 gacgttcgta gttccgacat tgacaggttt taatattgag ctggcgacag gcgacgttag
    30481 tgaagtagat ttcgtcggtg tcttcatcca tcagtttatg caggcaacac tgaccgcaac
    30541 catcacacaa cgactcccat tctgcatcgc tcatttcgtc cagggtttta ctttgccaga
    30601 aaggtacatc gctcatcagg tgttccgcca ttacgttaaa acgcacctta taaccagtct
    30661 ggcacagcga tgcaagtttt gccgccgctt tcaggcggca aaaagtatta caaaacgcga
    30721 gttgtcaaag aatgcccatc gaaagtgact gtcagctcat caccgctttg caacgggccg
    30781 acaccatcag gcgtgcctgt cagcacaacg tcaccgacct tgagggtaaa aaacttgctc
    30841 atataagcga tcagcggaac gattttatgg atcatgtccg cagtcgtacc ttgctggcgt
    30901 tgctcgccgt ttacgctcag gcccagcgtt gtattttgcg ggtcgccggt aaattccgcc
    30961 gcgggaataa acccggaaag cggacaagag ttatcaaacg ctttggcctt ttcccacggc
    31021 tgcccggctt tcttcatttt tccctgaaca tcacgcaatg tcagatcgag cgccacgccg
    31081 taaccggcaa tggctttgcg gacatgctct tccgtagcct gacgcagcgt cgcgccaatc
    31141 aacaccgcca gttcgacttc atgatgaact gaaccgaaat cggatgggat cgccaatggc
    31201 tgccgcagat cgcacagtgc cgtttctggt ttaataaaca gcactggctc ttcgggtact
    31261 gcgctgccca tctctttaat atgtttggca tagttactgc caacacagac tactttactc
    31321 accggataat ccagcagcgc accttgccag ttgtgatgtt gatacataac gttcccctca
    31381 ccttatcgtg gatatgaaaa cccgcgccga caaagataat gccaccgccg gatatcggtt
    31441 atttgttagt gtcgtctgtt ttctgcccca tgacggaaag atgttgcttc agcaaatctt
    31501 cgggtggtgg cggtaactgc aaatagtaac cttgctcggt taatgcctgt ttaacctttt
    31561 caatatcggc attgaccagt ttcttccgcc catccagcgg aagaatcatc gctaactgag
    31621 gctgaccaaa acctttcatc agttcctcag gaacacgcga aaaatcgtct tttttttcga
    31681 catataaata ggtctggtca cgtttgctgc ttcgataaat cacacaaaac atacttttac
    31741 tctttaagat gccaggtttt ggcataagct aacatcaatg aaacccgcgc cacaagccag
    31801 ccagctgtag atttctacgg tttgttcagt ccatgccccc tttataagta atcccccggc
    31861 aaaaatgccg cgccaggatt taaccgaaca caggaaagcc actggaattc tcccgtgaag
    31921 gattgttata ttataacagt tcatcgtact cattctgaac aggagactac caatgaaaat
    31981 taagggcatc agtaaggctg tattgttgct tgcactgcta acttccacga gctttgctgc
    32041 gggtaagaat gtcaatgttg agttcagaaa aggccatagt agcgctcagt actccggcga
    32101 aataaaggga tacgattacg atacatatac cttctatgcc aaaaaaggtc agaaagtgca
    32161 tgtgagtatc tctaatgaag gcgctgatac ttacctcttc gggccaggaa tcgatgattc
    32221 tgttgattta tccagatatt ccccagaact cgatagtcac ggacaatact cactccctgc
    32281 ttctggcaaa tatgagctgc gagtgctgca aacccgaaac gacgcccgta aaaacaaaac
    32341 taaaaaatat aacgtcgata ttcaaattaa gtaaatgtca accgacgggg actctccccg
    32401 tcataaacgt taacgccaca ctcctctctg tcgcttaaga ggttaatgac gaatagaaca
    32461 taatgtaaac aagacatcac tcacgacaca taaataacat ctttgtggtg gtttgattga
    32521 tttttccact ccgcttacca tccacaccaa aataacgatc atcacgacat aatttttctt
    32581 taacatcgca aaatacaccg ttagagaatg taaattcgct gggatcgtag ccttgtaatg
    32641 attgtaagtt ttcagcggct ttttcgccga gatatttcct tgttaactct ggggaaatgc
    32701 catctgaact cacacaaata tacgggtcgc aaacaacgcc acacgcagga gattgaagcc
    32761 cgccagcgtc atttccagac gccattgatg agaacatcat ccccacacct gacaatccga
    32821 tataaaaaat acgcatcata ttcatagcac atcctgataa tccaaccgta caacacttat
    32881 gctcatttca tcatcaatcc gtaatcaaaa ccgctgacct ggacgagtta cgatgacctg
    32941 acagaagtat cagacgtctt ctgcggtttc tatgatagag caattctgcg gcggatatta
    33001 agataacggg tatctgttct ttaatgatgc tgcaaaaaat ggaaagttaa gaaagcctgg
    33061 cgtggtgaaa aaatacactc gcctcaatac tggatattta aacaggtctg aagatgctgt
    33121 cacgattagg gtgcggaaaa aggaagcgta aataagaaca atcaaaagta cgacggcaat
    33181 gggttgattg acaagggtat tttttaagct atgaatcaac gccatttatc acagaataga
    33241 cttttactct gaataaatgg gagggtgact tgcctcaata taatccagac tataacatgc
    33301 cttatagtct tcggaacatc atcgcgcgct ggcgatgatt aatagctaat tgagtaaggc
    33361 caggatgtca aacacgccaa tcgagcttaa aggcagtagc ttcactttat ctgtggttca
    33421 tctgcatgag gcagaaccta aggttatcca tcaggcgctg gaagacaaaa tcgctcaggc
    33481 ccccgcattt ttaaaacatg cccccgttgt actcaacgtc agtgcactgg aagacccggt
    33541 aaactggtcg gcgatgcata aggcggtttc ggcaactggt ttgcgggtta ttggcgtaag
    33601 tggctgcaaa gatgcgcaac ttaaagccga aattgaaaag atggggctgc ctatcctgac
    33661 ggaaggaaag gaaaaatcgc cgcgtccagc ccccgcaccg caggctccag cgcaaaatac
    33721 aacgccggtc acaaaaacgc gtttaattga taccccagtg cgttccggtc agcgtattta
    33781 tgctccacaa tgtgatctga ttgttacaag ccacgttagc gcaggggccg aattgattgc
    33841 cgatggtaac attcatgtct atggcatgat gcgcggtcgt gcgctggcag gggcaagtgg
    33901 tgaccgggaa acgcaaatat tttgtacgaa cctgatggcg gaactggtgt ccatcgcagg
    33961 tgaatactgg ctgagtgatc aaatcccagc agaattttat ggcaaagcgg cacgactgca
    34021 gttagtcgaa aacgctttga ccgttcaacc gttaaattga tcccttttta acaaggaatt
    34081 tctatggcac gcattattgt tgttacttcg ggcaaagggg gtgttggtaa gacaacctcc
    34141 agcgcggcca tcgccactgg tttggcccag aagggaaaga aaactgtcgt gatagatttt
    34201 gatatcggcc tgcgtaatct cgacctgatt atgggttgtg aacgccgggt cgtttacgat
    34261 ttcgtcaacg tcattcaggg cgatgcaacg ctaaaccagg cgttaattaa agataaacgt
    34321 actgaaaatc tctatattct tccggcatcg caaactcgcg ataaagatgc cctcacccgt
    34381 gaaggggtcg ccaaagttct tgatgatctg aaagcgatgg attttgaatt tatcgtttgt
    34441 gactccccgg cagggattga aaccggtgcg ttaatggcac tctattttgc agacgaagcc
    34501 attattacca ccaacccgga agtctcctca gtacgcgact ctgaccgtat tttaggcatt
    34561 ctggcgtcga aatcacgccg cgcagaaaat ggcgaagagc cgattaaaga gcacctgctg
    34621 ttaacgcgct ataacccagg ccgcgtaagc agaggtgaca tgctgagcat ggaagatgtg
    34681 ctggagatcc tgcgcatcaa actcgtcggc gtgatcccag aggatcaatc agtattgcgc
    34741 gcctctaacc agggtgaacc ggtcattctc gacattaacg ccgatgcggg taaagcctac
    34801 gcagataccg tagaacgtct gttgggagaa gaacgtcctt tccgcttcat tgaagaagag
    34861 aagaaaggct tcctcaaacg cttgttcgga ggataagtta tggcattact cgatttcttt
    34921 ctctcgcgga agaaaaacac agccaacatt gcaaaagaac ggttgcagat tattgttgct
    34981 gaacgccgtc gcagcgatgc agaaccgcat tatctgccgc agttgcgtaa agatattctt
    35041 gaggtcattt gtaaatacgt acaaattgat cctgagatgg taaccgtaca gcttgagcaa
    35101 aaagatggcg atatttctat tcttgagctg aacgtgacct taccggaagc agaagagctg
    35161 aaataagccc cctgtaaaag cgcatttatc ttcaaggcag agtcatctct gccttgagtt
    35221 tttcatccct ctcatccacg ttgtggtaaa gcggcgagta ttcttgctga tactactcat
    35281 tgctatttcc ccccccttta caccttaagg ctgttcccac gcacagaaca aaatgtttac
    35341 gcctggttga gtaaataacc ttattgttag catgggtatc cagggagatg ataacccgca
    35401 atttcattat tcattgttct ccaataggat gaggtttccc gccgtaactg gcgggctttt
    35461 tttgccccag aattttccct tttagcaccc tgtaaacgaa aacagcgccg aaacgcagtt
    35521 aatcgttgat ggtcagaacg gccagttcac accggccacc gcattccacg gggactccac
    35581 accggcacca cggttatacc caccccgaga tgcccgctta acatactgct gaatgaggct
    35641 ttaatacctg cctggtatat tccacgtctg cccgacaaat cattgacaaa attaccgtca
    35701 ctattcacct tcacccggtt atcatcgaca aattctttgc gcacagccgc cttcagccag
    35761 ggttcaattt ccataccgtt ccccagacgc atgttgtagc tcagcgttgc gcccagttca
    35821 cgatatatac tgcgggtatc gactgatttc gattccatgc attggataaa tgatagtagc
    35881 gtctaagtga ccttagctct gctgcaacat cagcccgcag gcaccagacc aggggattca
    35941 tcctgaagag acagcgcaaa tgtattgtgt tcaccgctca tcaaagacat catgatgaaa
    36001 tgatgatatc ccgtataaga aagaggcatt ttttaaacgc agtgcgctga agtgttgttg
    36061 gataaaaaac actcttttct gataatactg tcgtacgctt atttttcgac aatgaggccg
    36121 tccacaaaat aaaatgacta atgtaatcgt tgctaatgaa tatcttctgc tcacataaca
    36181 atcacacaat aatattgata aatcagatta tcttaccttt acaacattgt attaacagcc
    36241 aatgacactt cttgaataaa aatattgtca atcaatgagt tatttctcat ttgagattat
    36301 tctcattccc gtaaaaaaca taattcctat catcacagtc acgctcattt tgaattatct
    36361 gaataatagc gagcgttctt tagttaagca gatcttaatt gaagacgaaa ttattgtgtg
    36421 tgcaacttac ttaataccgg acaactaagt tgaagaaaaa aatactcgcc ttcgggctta
    36481 tctcagcatt gttctgctcc acgccagcaa tggcggatat gaatcgcacc acgaaaggtg
    36541 cattgctagg tgcaggcgtt ggtttactta ctggcaatgg tgttaatggc gtactgaaag
    36601 gtgcagctgt tggcgctggt gttggtgcag taacagaaaa aggccgtgac ggtaaaaatg
    36661 cgcgtaaagg tgcaaaagtg ggtgccgccg ttggtgctgt cactggcgtt ctgaccggca
    36721 atggcctcga aggggcgatt aaaggtgccg tgattggcgg tacgggtggt gcaattctgg
    36781 gtaaaatgaa ataaggaatg atgatgaaaa aatttgcttt actggcgggt ctgtttgttt
    36841 tcgcaccaat gacctgggcg caggactaca atattaagaa cggtttgcca tcagaaacct
    36901 atattacttg cgcagaagcc aacgaaatgg caaaaactga cagcgcacag gttgcagaaa
    36961 ttgttgcggt aatgggtaat gccagcgttg ccagccgtga tttaaaaatt gagcaatctc
    37021 cggaactgag cgccaaagtg gtagaaaaac tgaatcaggt ttgcgctaaa gatccgcaaa
    37081 tgctgttgat cacggcaatt gatgacacca tgcgtgctat cggcaaaaaa taatatttca
    37141 tatgttaccg cgtcgatgaa ttcgacgcgg ttttttagct aacgggcggg atcagaactt
    37201 atatttcagg cccaccatca ttgcggtgtc attgtagcca ttatcaccca gctgcacgcc
    37261 cacattaccc cagacgctgg ccgccggatt cagattgcca tttacgccat gtttcatttc
    37321 ccccagatta cgagccccgt cttgttcgac tttcacaccg ttcattgaga cagcaaaatc
    37381 tttactgtta tggatcccgt tcatttcaac aaaaggttca aagtcgtcac cgtgcggacc
    37441 gctgtttttc tcctgagtac gaataaaggt gcggaaacca agtcggctct ggatgttgta
    37501 atttgcgtca ttctcaatac gtgagccatt ggcttccgtg tgcgcattat gatcgacgcc
    37561 catccagatg gcctgtgccg aggtcgttct caactgtccg ttgctgtcac gccaggcatt
    37621 atgcccgcca atttgacata gccaaagttg gcttgaacgc tcctgttcag ttacaggatc
    37681 gatatagcgc gtttcacccg cacgatcgtt cagacgcgta acaaaaagag tgttagcggc
    37741 tgccaggttg gcgacgtaac tgccagcgtc gggtcgcagg acgggggtag gcgtttctgt
    37801 tgattctgaa gtgacattgg aaaaaaatca ctctctacca ttgtatattt ttgcaatggg
    37861 ggctttagtg ccatttgttg taatagaact tttttatatc aatgttacct tgtcgaatag
    37921 caactgcata acttccatca gccacagttt caagtaccac ataatctaaa ttaatatatg
    37981 ctttattccc attagcataa gtaccatagc tattaatacc attagttgtt atggaaccac
    38041 cattcatttt taaatcagca cggctaataa cttcgtaact gttagaatca caaacttcat
    38101 catctacagc atcgacacat gttcgagact ctccaggact tgaacatgca agaactccta
    38161 ctgcattttc cccataggta acaatgttcg ttttatctgt ggtttcaaga ctggtgttat
    38221 tttccacagt cccagaatca ttaacctgac ttaaaaatcc cgctgaatat gccccctcgt
    38281 ctcgactgaa ttatcaccat tcataacgat ggtgccacca aattcactga ctactgcgct
    38341 ggctgttatc cctccatttt ctttgtcaga tacgcttcca gaggtcttaa tattgctatc
    38401 gcttatatat aatactttgt tttggctatc aacagaaata ccataagatc catcaccact
    38461 agtcatcaca ctggcattat ttatatatcc agttacaccg tcatccactt tcacagcatg
    38521 gctttcgtct taagtgatta gatactctcc attacttgta gaagtattat ttttgatttc
    38581 aatcggtgat tcttcatcgg ttatatagga aattacacta taattatcca acaattgtgt
    38641 tacccaccgc cagagcaata agtcctaaac tgaacccggg gagttttttc agtttcatag
    38701 attaaccatc cattcattgg attaacaaat attcctgata aaataaccta tgagttcaga
    38761 tcaccaaaac ggagggcaaa gataaaaaca aaagcacaat aaatttaaat agataaacag
    38821 cgacaatatt taaatgataa ataagtcagc attatcattt ttagcttatt ttcatgacat
    38881 tgatcacttt ggggtaacta ttttgtttaa caaataactc ttcgacatca aaattatcaa
    38941 cagttgccat agaaattatt tcactgatat ataaaacaac tgtgataaca ccagggttga
    39001 caactatttg cacaataatt cctttccttc aatgatccag gggttcactg ccagcaaccc
    39061 attcagccgc atactgacag tgagaaactg aaagattagt gctgatccct gtggctgacg
    39121 agtctttccc ttaatcgatt aaccagattg atcgccagcc aaacaagggc attaagcaaa
    39181 tttatcgtca caagcacttc tcccagcccg gtgctgggtt ttgcaataag gatgaccagg
    39241 agagtgatca acataaatgc aatggaaaag atgatataga gagtgaaata atccagatta
    39301 ttactattgt tcatgctact aatggcaatc cagtcaaaac tttcaaacaa ttatagcaaa
    39361 caaaagaatg aacaatagta acaagaggca acgagctaat tagctgtcta taattacacc
    39421 gtaccatggc cttactgatc aattttcact caaccacaac cttcaccttc ggtttagaaa
    39481 ggataatttt gaccaggtcg atgtatgtaa caggtttata gaaataataa ccctgctgaa
    39541 atgtaatatt attttggttc agatagtcaa gttgttcttt cgtttcgaca ccttcagcga
    39601 cgatactgat cgaaagttta cgcgccagat ccaatacaca atccagaatt cgggttgatt
    39661 ctgggtctgc gttgacgcgg ccaacgaaac tgtgatcaat ttttatataa tcaatatgca
    39721 ggtcatgcag ataagaaagc cctgagtaac cagtaccgaa atcatccagc gcgatgacaa
    39781 aaccattttc atgcagaatg ttcaaccgct gaaccagact ttcatcaaca tttaatggtt
    39841 cacgctcggt gacttccaga acaaggttta aatcgcggcg ggtaaaactg tcacggtaat
    39901 ttaagcactc gtcgacaaac gtcggcgaaa caatatgcga ggcgctaaaa ttaatcccaa
    39961 tatgaaaacc ttccggcagt ttactcgcga tagcgttcat ctgggtggca acctgattca
    40021 tcaggctttg cgtaagcgga acgattaatc cgcatttttc agcaagtgga ataaatgccg
    40081 caggtgatat atatccaccg tgaggttgtt tccagcgggc taacacctca actccccgca
    40141 atgtcccttc ccgaccattt accacaggtt ggtaaaaagg gacgatctcc ccattattta
    40201 tagcccgtcg caggatctct tcaggcgttg cgcttttatt gaaataccta tcaagaagga
    40261 aggcagcggc gcaggcgatt aacagaataa atatcaaaat cccaaagcct ttatcgataa
    40321 gtctgtagaa gctaaagaga cgttcattcg ctcgcgctgg ggtctacaga tagcatggta
    40381 gagagcatca caaatatcca cgccgaagat aaaattttct ccaacttcat ctaacctatt
    40441 aattatttag aacaatgtag gcagaattaa acaaattagg cgggatatca ggcgtcaaga
    40501 atggaaaacg agcgctctcc attcctgttt gccctctgat attgcggata tattaagaaa
    40561 gcataacgcc tgaaatgctc actttgcatc agcatagtga tacagctgat gtttattcaa
    40621 aaaccttact caagttttaa gagagcacgg attccctgtc attaataatg atatccgtta
    40681 gtgtagtctt atgcatttca atgtactgca agatttgcag atagagatca gaaagaataa
    40741 cactggtctc atcttttaaa cgcaaccgta aagcatgagc aataatatga ctatcaacat
    40801 atccatgtgt catgaacacc tccttctcga ggtttttaaa caaagcacat tgaaaaataa
    40861 atctctctgg gattgaatta ttcatgtcag cctcgcagga atagtgaccc aataaaatta
    40921 tgctatgtat agtctaaagc gacagacaaa aataagatga atgagttttc tataaactta
    40981 tactttataa ttaaaagtta catatcatca gctgtgtatc gcaacacgat ttccagtgtt
    41041 tttctaatca catcagcttt gagaatatca cttgttgttt ccagggagtg tatcagactt
    41101 aagataatat ttttattatt aacattatca cctgaaagca ttaaattggt cacagcctgc
    41161 cctaacacag ctgactcttc ttctaacaaa ttacctgaac tacgaaagta acttgataac
    41221 gctttatcag atattgcatt atgaatagta gtatcttcaa gcatggtaac ctctcatctt
    41281 acttatgaaa ttttaatgta ttctgtttat tttcttacca gtgaacatat ttttattgtc
    41341 agcgatcgct gttcttcggt ttggccctcc tgtatcactg ttgctaaaat cacgaattat
    41401 gctgtcaatt aaatctcgtc ggaaagtatt ttcctcagcc gatttcatta cgagtaattg
    41461 cttaataaga gtctgcaacg aaaaatttat cttcatgcgc agtatctgga gcaccgcctg
    41521 gccagtaatt tcatatttaa tactttcatt atcagatgtc ttcataacga cttcatagct
    41581 aacctgttaa ataatcaggc tgttgcatta ttcaaaaagc aacccaatta gtgcattata
    41641 atgtttctgt tcctcttccc ctgtcgcttg ttccagtcgg caaagaagtt tggcacaaag
    41701 cgactttcga ctcagattac gtccatcttt caaaatctca gtcacaattt ccccgagagt
    41761 ttcctgctga gtaggcaagt tagcttttgc aaagtaacga gtgattgctc ctgcagaatc
    41821 tgaagtcact gaattttgat gcatgctacg cctctgttaa aaatgttaat caatgttaag
    41881 tgaggtaaca atagcaaact tgtacgaaat atgtgtacag aatgataaat taatttttcg
    41941 caattagtgc taattcatat aaaacaatgc attacgataa aacatattgc atcatttaaa
    42001 tgacaaccta tacaggtttt ttcaccaaac cgtcttcaac cttttccact ttttatcaat
    42061 gtaaagaaac ggttatgttt tggtattaaa agaaagacac aagaagatat gtctgttacc
    42121 gtcttactct cgcctcgccc attaccctgg attgttaatg cttaccaccc ttatttatcg
    42181 tagccatata cgtgacgccg aacctgtcaa aaaaatcgaa gaaatggttt cgatagcaaa
    42241 tcgcaggaac atgcggtctg acgtaacagg gatcttactg tttaatggtt ctcatttttt
    42301 ccagcttctg gaaggtccgg aagaacaggt tcaaatgata tatcgggcca tatgccagga
    42361 tccacggcac tataatattg ttgaactgtt gtgcgattac gcgcctgctc gccgttttgg
    42421 caaagcagga atggaattat ttgatttacg cctgcacgag cgagatgacg ttttacaggc
    42481 cgtattcgac aaaggcacat caaaatttca gctaacttat gatgacagag cgctacaatt
    42541 ttttcgtact tttgtccttg caactgaaca atcaacctat ttcgagattc ctgctgaaga
    42601 ctcctggctt tttatcgctg acggatctga taaagaactt gattcttgta ccctttcatc
    42661 aaatataaac gaccactttg cctttcatcc tattgtcgac cctttatcgc ggcggataat
    42721 cgcttttgaa gccattgtgc aaaaaaatga agacagcccg tcagctatag cggttgggca
    42781 gcgtaaagaa ggggaaatct acacagcgga tctcaaaagt aaggcgcttg cattcgcgat
    42841 ggcacacgca cttaagctcg gtgataaaat gatttcaatc aatctattac ctatgaccct
    42901 ggttaacgag cctgacgcag tctctttttt acttgatgaa ataaaggcca atgctctggt
    42961 gcctgaacaa atcatcgttg aatttactga aagtgaagtc atatctcggt ttgatgagtt
    43021 tgccgaagcg gttaaatcgc taaaggctgc cggtatcagt gtagcaattg atcattttgg
    43081 cgcaggtttt gctggtttgt tactcctgtc acgcttccag cctgacagaa ttaaaatcag
    43141 tcaggaattg attaccaacg ttcataaaag cggaccacgg caggcaatta ttcaggcgat
    43201 catgaaatgc tgtacatcac ttgaaattca agtctctgct atgggcgtgg caacaccaga
    43261 agagtggatg tggcttgaat ctgcaggaat tgagatgttt cagggagatc tgttttccaa
    43321 agctaaattg aatggtatcc cttcagttgc gtggccggag aaaaaataat tttcagcaca
    43381 ttatttcgca tgatttctgg aaatcatcgt gaaaatgaat acgttatgtt ttaatttaat
    43441 ccacattaaa aa
//
LOCUS       DAPOXO010000038        42952 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPOXO010000038 DAPOXO010000000
VERSION     DAPOXO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42952
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.038"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(95..3976)
                     /gene="entF"
                     /locus_tag="ROH59_002441"
     CDS             complement(95..3976)
                     /gene="entF"
                     /locus_tag="ROH59_002441"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HDX4804911.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSDLPSAWSVAHYVELTGEVDAPLL
                     ARAVVAGLAQADTLRMRFTEDNGEVWQWVDDAQTFELPEIIDLRTNIDPHGTARALMQ
                     ADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCAL
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAAQETLPQLATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGEEPLFGPVLNIKVFDYQLDIPGVQAQTHPLATGPVNDLELALFPDEHGDLSI
                     EILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQINATQI
                     EIPETTLSALVAEQAAKTPDAPALADARYQFSYREMREQVVALANLLRERGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     ADVPDLTRLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASLTPQTARQNCSTLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAEVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQTPGRVP
                     KAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQFARQVTPGQVM
                     VASTVAKLATIIDGEEDSTRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPQWSIIGIQSPRPHGPMQTAANLDEVCEAHLATLFEQQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVAFDGKATLFVAERTLQEGMSPEQAWAPWIAEL
                     DIYRQDCAHVDIISPEYFKEIGPLINTQINN"
     gene            complement(3973..4191)
                     /gene="ybdZ"
                     /locus_tag="ROH59_002442"
     CDS             complement(3973..4191)
                     /gene="ybdZ"
                     /locus_tag="ROH59_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis protein YbdZ"
                     /protein_id="HDX4804912.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCALPAGWDVVCQPQ
                     SQASCQQWLEAHWRTLTPANFTQLQEAQ"
     gene            complement(4194..5396)
                     /gene="fes"
                     /locus_tag="ROH59_002443"
     CDS             complement(4194..5396)
                     /gene="fes"
                     /locus_tag="ROH59_002443"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HDX4804913.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEGHS
                     AIKRVWVYITGMTDHHQNSQPRSMQRIAGTDVWQWTTQLNANWRGSYCFIPTERDDIF
                     SAPSPDRLELREGWRKLLPQAIADPLNPQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PETPAKEIIWKSERLKNSRRVWIFTIGDATAEERPLAVLLDGEFWAQSMPVWPALTSL
                     THRRQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPQVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGHQEGMLLEQLKTGEVSAEG
                     LRIVLEAGVREPMIMQANQALYAQLHPLKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            5434..5634
                     /locus_tag="ROH59_002444"
     CDS             5434..5634
                     /locus_tag="ROH59_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804914.1"
                     /translation="MQKYIDNIIDNYLHLQYRNGAPWEARTLINQLHCVSFRIKGFRG
                     SGMRRVDDDHARQLQFVAKMQE"
     gene            5639..7879
                     /gene="fepA"
                     /locus_tag="ROH59_002445"
     CDS             5639..7879
                     /gene="fepA"
                     /locus_tag="ROH59_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HDX4804915.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDAYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKAAQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     KNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SINTHF"
     gene            8054..8713
                     /gene="entD"
                     /locus_tag="ROH59_002446"
     CDS             8054..8713
                     /gene="entD"
                     /locus_tag="ROH59_002446"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002430230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HDX4804916.1"
                     /translation="MKTTHTSLPFAGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGR
                     KRKTEHLAGRIAAIYALREYGYKCVPAIGELRQPVWPTGVYGSISHCGTTALAVVSRQ
                     PIGIDIEEIFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKACER
                     QTDAGFLRYQIRNCQHQQMNISGPNGDHIVQWLVRGNNVITLCLADKHPHTAACGLSG
                     G"
     gene            complement(8715..9650)
                     /locus_tag="ROH59_002447"
     CDS             complement(8715..9650)
                     /locus_tag="ROH59_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003831178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDX4804917.1"
                     /translation="MRNSEHLANVMVQAFIDAVNEGIDLVPVVADSTSTAKIAPFIKQ
                     FPDRLVNVGIAEQSMVGTAAGLALGGKVAVTCNAAPFLIARANEQIKVDVCYNFTNVK
                     LFGLNAGASYGPLASTHHAIDDIAVMRGFGNIQIFAPSSPRECRQVIDYALRYQGPVY
                     IRMDGKALPEIHDEDYRFVPGAVVTLREGSELALVATGSTVHEVVDAAELLAQSGIAA
                     TVVSVPSIRPCDTKALLAALKGCKAVMTVEEHNVNGGLGSLVAEVLAEAGTGITLKRA
                     GIMDGEYAAAADRGWLRQHHGFDAAGIAAQAREML"
     gene            complement(9643..10473)
                     /locus_tag="ROH59_002448"
     CDS             complement(9643..10473)
                     /locus_tag="ROH59_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDX4804918.1"
                     /translation="MNPYSYDIQTLERKARAVRRHIVRLNANSPAGGHTGADLSQVEL
                     LTALYFRILNVAPDRLHDDDRDIYIQSKGHAVGCYYCVLAEAGFFPLEWLSTYQQPNS
                     HLPGHPVRQKTPGIELNTGALGHGFPVAVGLALAAKKSQSRRRIFLITGDGELAEGSN
                     WEAALAAAHYGLDNLVIINDKNNLQLAGPTREIMNTDPLAEKWLAFGMQVTECQGNDM
                     ASVVATLEELKQEGKPNVVIAHTTKGAGISFIQGRAEWHHRVPKGDEIEQALEELKDA
                     "
     gene            10836..11786
                     /locus_tag="ROH59_002449"
     CDS             10836..11786
                     /locus_tag="ROH59_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDX4804919.1"
                     /translation="MAKQDEQRLLVKIATLYYLEGRKQSDIAQLLSLSQSFISRALTR
                     CQKEGVVKISVVQPSNIFLNLEKGIEERYGIKQAIVVDTEDDASDHTIKRAIGSAAAH
                     YLETRLRPKDFIGVSSWSSTIRAMVDEVHAQNLKASGVIQLLGGVGPNGNVQATILTQ
                     TLAQHLNCEAWLLPSQSIEGSVEEKKRLVASQDVADVIARFDDVDIAIVGIGILEPSQ
                     LLKTSGNYYHEDMLQVLADRGAVGDICLHYYDKHGQPVLQDDEDPVIGMALDKIKKCP
                     NVVALAGGKDKVAAIKGAMQGGYIDVLITDFPTARMLIAD"
     gene            12137..13657
                     /locus_tag="ROH59_002450"
     CDS             12137..13657
                     /locus_tag="ROH59_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDX4804920.1"
                     /translation="MFAGNKEFVIALDEGTTNAKAIALDGFGNVVAKFSQPLAIQTPR
                     EGWVEQSGEALISASLDVIAQAINHVGAENVAALAISNQRETAIGWYRQSGKPLNAAI
                     TWQCTRSAEFCETLRREGKEQQIKTTTGLPIAPLFSASKMRWLLESTPEGVQLADQGE
                     ICLGTIDAWLLWNLTAGDSFCCDYSNAARTQLLNLKTGEWDEEMLALFHIPRAALPEI
                     KPSSGLFGYTRGLKTIPDGIPVMAMVGDSHAALFGHALGEAGCVKATYGTGSSVMAPV
                     NSAQCDIATLATTIAWHDGENIIYGLEGNIPHTGDAVAWMADSTGLSELTDAELALEL
                     NTLPASVDSTMGVYFVPALTGLGAPWWDDSARGVVCGLSRGVKRAHLIRAALESITYQ
                     IADVVEAMQQHDDFHLSALMVDGGPTKNDWLMQYQADLLGCPVMCSDVPELSAIGAGL
                     LARKALIPGTVADLKALLTEHSEFKPDMARHQRLQKRWQEWRHAVNRTLWKPASSI"
     gene            13761..14696
                     /locus_tag="ROH59_002451"
     CDS             13761..14696
                     /locus_tag="ROH59_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4804921.1"
                     /translation="MKLRLTLLTAATLTALSFSAHAVEKGTIMIMVNSLDNPYYASEA
                     KGASEKAQQLGYKTTILSHGEDVKKQNELIDTAIGKKVQGIILDNADSTASVAAIEKA
                     KKAGIPVILINREIPVDDVALVQITHNNFQAGSEVANAFVEKMGEKGKYAELTCNLAD
                     NNCVTRSKSFHQVIDQFPEMVSVAKQDAKGTLIDGKRIMDSILQAHPDVKGVICGNGP
                     VALGAIAALKAANRNDVIVVGIDGSNDERDAVKAESLQATVMLQAQAIAAQGVTDLDN
                     YLQKGVKPAKQRVMFRGILITKDNADKVQDFNIKS"
     gene            14743..15363
                     /locus_tag="ROH59_002452"
     CDS             14743..15363
                     /locus_tag="ROH59_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004111235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2291 domain-containing protein"
                     /protein_id="HDX4804922.1"
                     /translation="MDKKVWLALAILSLGGCRIVSQQELADLKSPPNPHMANIDQTWQ
                     KNIVPQVVENARPVAELMAALQAEKDVDAACKTLGYRSQEENPCIFYVKVEGSITNID
                     AKSRSGKMTITDISGTNIVVQTGPTLRGTLLRDAYKGASYEHFNDQVLFGEYGRAINE
                     QAINMIQSAKLKTGETVQVYGVFSAWDIPQTIPDITPAKIARAGGE"
     gene            15365..16909
                     /locus_tag="ROH59_002453"
     CDS             15365..16909
                     /locus_tag="ROH59_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDX4804923.1"
                     /translation="MLPQEIAPPQTDESPVIIETHDLSRIYPGVVALDNVNYRVYRNK
                     VNVLIGENGAGKSTMMKMLAGVETPSSGKIILDGKEVTLNSTHQAEKHGISIIFQELN
                     LFPNMNVMDNIFMANEFFQKGKINEKYQYELAKSLLERLELNVDPYTQLGELGIGHQQ
                     LVEIARALSKDTRVLIMDEPTSALSQSEVKVLFNVIAQLKRRGVTIIYISHRLEELME
                     IGDFITIFRDGRFISERAVSDASIPWIIEQMVGDKKKHFDYQPATQGDTVLAVQGLTA
                     LHPSGGYKLNDVTFSLHKGEVIGIYGLLGAGRTELFKGLVGLMPCQSGKIQLNGETID
                     KCHFQARLKKGLALVPEDRQGEGVVQMMSIQSNMTLSDFSLQGFRRAWKWLNPQKESA
                     SVKEMILQLAIKVSDAELPITSLSGGNQQKVVLGKALMTQPQVVFLDEPTRGIDVGAK
                     TDVYQLVGKMAQQGLAVMFSSSELDEVMALADRILVMADGRITADLPRGEVTREKLIA
                     ASTPQD"
     gene            16927..17994
                     /locus_tag="ROH59_002454"
     CDS             16927..17994
                     /locus_tag="ROH59_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4804924.1"
                     /translation="MNQKYMIYMYLLKARTFIALLLVIAFFSVMVPNFLTASNLLIMT
                     QHVAITGLLAIGMTLVILTGGIDLSVGAVAGICGMVAGALLTNGLPLWSGNIIFFNVP
                     EVILCVAVFGILVGLVNGAVITRFGVAPFICTLGMMYVARGSALLFNDGSTYPNLNGM
                     ETLGNTGFATLGSGTFLGIYLPIWLMIGFLILGYWITTKTPLGRYIYAIGGNESAARL
                     AGVPIVKVKVFVYAFSGLCAAFVGLIVASQLQTAHPMTGNMFEMDAIGATVLGGTALA
                     GGRGRVSGSIIGAFVIVFLADGMVMMGVSDFWQMVIKGLVIVTAVVVDQFQQKLQNKV
                     ILMRRHEEKMAAAPAVKPLSS"
     gene            18048..18845
                     /locus_tag="ROH59_002455"
     CDS             18048..18845
                     /locus_tag="ROH59_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4804925.1"
                     /translation="MQRNFQGKTVVITGACRGIGAGIAERFARDGANLVMVSNAERVH
                     ETAEQLRQCYQADILSLEVDVTDEAQVQALYEQAAARFGSIDVSIQNAGIITIDYFDR
                     MPAADFEKVLAVNTTAVWLCCREAAKYMVKQNHGCLINTSSGQGRQGFIYTPHYAASK
                     MGVIGITQSLVHELAQWNITVNAFCPGIIESEMWDYNDRVWGEILSTDDKRYGKGELM
                     AEWVEGIPMKRAGKPEDVAGLVAFLASDDARYLTGQTINIDGGLIMS"
     gene            18878..19663
                     /locus_tag="ROH59_002456"
     CDS             18878..19663
                     /locus_tag="ROH59_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4804926.1"
                     /translation="MIAKDFAQQLFDLHDRVAFVTGAGSGIGQMIALALASAGARVVC
                     FDLREDGGLKETVNHIEALGGQALYYTGDVRELRDLRAAVALAKTHFGRLDIAVNAAG
                     IANANPALEMESEQWQRVIDINLTGVWNSCKAEAELMVENGDGSIINIASMSGIIVNR
                     GLEQAHYNSSKAGVIHLSKSLAMEWVSKGIRVNSISPGYTATPMNTRPEMVHQTREFE
                     SQTPIQRMAKVEEMAGPALFLASDAASFCTGVDLVVDGGFVCW"
     gene            complement(19773..19925)
                     /gene="hokE"
                     /locus_tag="ROH59_002457"
     CDS             complement(19773..19925)
                     /gene="hokE"
                     /locus_tag="ROH59_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HDX4804927.1"
                     /translation="MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            complement(20275..20427)
                     /gene="hokE"
                     /locus_tag="ROH59_002458"
     CDS             complement(20275..20427)
                     /gene="hokE"
                     /locus_tag="ROH59_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HDX4804928.1"
                     /translation="MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            20870..21988
                     /locus_tag="ROH59_002459"
     CDS             20870..21988
                     /locus_tag="ROH59_002459"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDX4804929.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDTVKNQ
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FISLSAASPYMQGTDTRFASSRPNIFSAFPDNGPMQWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRSLTEATLRLLEKIAPSAHKIGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGE"
     gene            22054..22302
                     /locus_tag="ROH59_002460"
     CDS             22054..22302
                     /locus_tag="ROH59_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 domain-containing protein"
                     /protein_id="HDX4804930.1"
                     /translation="MKHPLETLTTAAGILLMAFLSCLLLPAPALGLTLAQKLVTTFHL
                     MDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSLAD"
     gene            22367..22750
                     /locus_tag="ROH59_002461"
     CDS             22367..22750
                     /locus_tag="ROH59_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDX4804931.1"
                     /translation="MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSS
                     ELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALLRDLIND
                     SWNLVVDGLAKRDQKRLRPDSTVNQ"
     gene            22829..23482
                     /gene="nfsB"
                     /locus_tag="ROH59_002462"
     CDS             22829..23482
                     /gene="nfsB"
                     /locus_tag="ROH59_002462"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HDX4804932.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAADNYVFNERKMLDASHVVVFCAKTAMDDAWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDEEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            23590..24837
                     /gene="ybdG"
                     /locus_tag="ROH59_002463"
     CDS             23590..24837
                     /gene="ybdG"
                     /locus_tag="ROH59_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel YbdG"
                     /protein_id="HDX4804933.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(24995..26377)
                     /gene="pheP"
                     /locus_tag="ROH59_002464"
     CDS             complement(24995..26377)
                     /gene="pheP"
                     /locus_tag="ROH59_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HDX4804934.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFV
                     AFKTLRRKVN"
     gene            complement(26479..29622)
                     /gene="cusA"
                     /locus_tag="ROH59_002465"
     CDS             complement(26479..29622)
                     /gene="cusA"
                     /locus_tag="ROH59_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HDX4804935.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVSDPQRLAQYGISLADVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQVGPEMRRGIA
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKNDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQDQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDTMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(29634..30857)
                     /gene="cusB"
                     /locus_tag="ROH59_002466"
     CDS             complement(29634..30857)
                     /gene="cusB"
                     /locus_tag="ROH59_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HDX4804936.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWFAKEEPPAEKTSTAERKVLF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFSQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEIDNADEALKPGMNAGLQLNTASEPMLLIPSQALID
                     TGNEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     gene            complement(30873..31205)
                     /gene="cusF"
                     /locus_tag="ROH59_002467"
     CDS             complement(30873..31205)
                     /gene="cusF"
                     /locus_tag="ROH59_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HDX4804937.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVV
                     KGVDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(31229..32611)
                     /gene="cusC"
                     /locus_tag="ROH59_002468"
     CDS             complement(31229..32611)
                     /gene="cusC"
                     /locus_tag="ROH59_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HDX4804938.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMAALKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGDSATTRELSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDITEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGGWQQ"
     gene            32768..33451
                     /gene="cusR"
                     /locus_tag="ROH59_002469"
     CDS             32768..33451
                     /gene="cusR"
                     /locus_tag="ROH59_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HDX4804939.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            33441..34883
                     /gene="cusS"
                     /locus_tag="ROH59_002470"
     CDS             33441..34883
                     /gene="cusS"
                     /locus_tag="ROH59_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HDX4804940.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLANSHGKTVYHSP
                     GAPDIREFTRDAIPDKDAQAGEVYLLSGPTMMMPGHGHGHMEHSNWRMINLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDECQVAGDPLMLRRALSNLLSNALRYTP
                     TGETIVVRCQTVDHLVQVTVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFVIILPA"
     gene            35033..37270
                     /gene="nrfB"
                     /locus_tag="ROH59_002471"
     CDS             35033..37270
                     /gene="nrfB"
                     /locus_tag="ROH59_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HDX4804941.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYHI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMINRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRALKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLDNDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     gene            37257..40229
                     /gene="nfrA"
                     /locus_tag="ROH59_002472"
     CDS             37257..40229
                     /gene="nfrA"
                     /locus_tag="ROH59_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HDX4804942.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDDRLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAAQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLIEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAEALRLARLLYQQEPASLTRLDQLTWQLMQN
                     GQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPDAWQHRAVAYQAYQVEDYATALTAWQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEQRGLGNNALYWWLHAQRYIPGQPELALNDLTRSINIAPSANAYVARATIYRQ
                     RHNIPAAVSDLRAALELEPNNSNTQAALGYALWDSGDIAQSREMLEQAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WSFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRLGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFLAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            40230..41120
                     /locus_tag="ROH59_002473"
     CDS             40230..41120
                     /locus_tag="ROH59_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HDX4804943.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRALLFKRATAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAVPGVTPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISIFFAGNMSPDGYRQLLEQVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSSAPASGIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAQSILEY"
     gene            41768..42721
                     /gene="ompT"
                     /locus_tag="ROH59_002474"
     CDS             41768..42721
                     /gene="ompT"
                     /locus_tag="ROH59_002474"
                     /EC_number="3.4.23.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease OmpT"
                     /protein_id="HDX4804944.1"
                     /translation="MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGK
                     TKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMV
                     DQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYS
                     FTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTF
                     KYSGWVEASDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYIEGAWNRV
                     TNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF"
BASE COUNT        10683 a        11185 c        10856 g        10228 t
ORIGIN      
        1 aaaataaata aattttaaga ataaaaaaac cataatcatt tagtcggatt atggttttaa
       61 atgaggttat ggcaagttct ttactaacgt acggttagtt attaatttgt gtatttatta
      121 gtggtcctat ttctttaaaa tactccgggg aaataatatc cacatgcgca caatcctgac
      181 gatagatatc cagctcagca atccacggtg cccaggcctg ttcaggactc ataccttcct
      241 gaagcgtgcg ttcggcaaca aatagcgtcg ctttaccatc aaacgctacg ctatgagctg
      301 tcgtcagcag gcgcacagca tcagcgtagt tgccttcaat ggtggtaaac aactccgttg
      361 aagtacttcc ctgctgtgcc gccaggaagg cttcgcgctc gcggttaatc tccgccagca
      421 cttccgggtc cagaccattg gcttcttttt cctgccagtt ttgcgtttct ggcggccagg
      481 tatccagcaa gccaagaaat gccacctgtt cgccacgggc acgcagtcgc gccgcaatgc
      541 cctgcgccag cgtaccgcca agtgaataac ccagcaggta ataagggccg tgcggttgtt
      601 gttcaaataa cgttgccaga tgcgcttcgc agacttcatc caggtttgcc gccgtctgca
      661 tggggccatg agggcgcggc gactgaatgc cgataatcga ccattgtgga tcgagataac
      721 gcgagagcac gctgaactgc caggcaaaac cggatgccgg atggaaacaa aacagcgtcg
      781 ggccattacc ttcacgcaac ggcagaatgg tttcgaatcc catgcgtcgg gtgctgtctt
      841 cttcaccatc aataatcgtt gccagtttgg cgacagttga cgcgaccatc acctgccccg
      901 gcgtcacctg acgggcaaac tgtcgactta actgcgctgc cagtttcatt gccagtagcg
      961 aatgaccgcc aagcgcaaag aaatcagcat cggcatcctg cacgtcacaa cccagcaacg
     1021 acgagaatgc cgcggcgata atcgtttcac tgcccgcttt cggcacacgc cccggcgttt
     1081 gtgccttcag ttcaggcaac ggtaaggctt tgcgatccag cttgccgttg gcgctaagtg
     1141 gtaactgtgg aagttgcagc agaaccaccg gtaccatatg tggtggcaat gtttctcgaa
     1201 gctgcgcctg taatgcgctg gtatccaacg gcagacctga ttgcgacacc agatagccca
     1261 ccaactgacg cgcatcacca ccagtggctg ccgcctggtt aatcacacag gcgtgggtaa
     1321 cggcttgttc gacatccggc agcgcctgca tcacgcgatc aatttcgccc agttcgatac
     1381 gctgcccgcg aatttttagc tgatcgtcac tgcgcccgag gtactccact gcgccgttat
     1441 ccagccagcg ggcaacgtct ccggtacggt acatccgttc acctggggca aaaggatcgg
     1501 caataaagcg gctggcggtc agatcgggtc gtccaagata cccctgcgcc agttgaatac
     1561 cggtgagata gagatcgccc gccacacccg gcggcaccgg atgcatcatc gcatcgagaa
     1621 tgcgcaggcc cgtattccac accggataac caatcggcac actgctgccg cgcacctctg
     1681 ccagttcctc gccaaaagcc ggataccaac tgacatctac cgccgcttcc gtcgggccat
     1741 atagattatg caacggcgcg ccggttaact gttgccattc gcggcataaa tcagccggta
     1801 gggcttcacc actacagaaa acctgtttca acgtcgagca attctgacga gcggtttgcg
     1861 gcgtcagcga tgcaacaaat gctgccagca tcgacggcac aaagtgcgtg gtcgttacac
     1921 catattcggc aaagaattgc tgcatagcga gcgggtcgcg gtgcgcttcc ggttcagcca
     1981 tcaccagttt agccccggca ataaacggcc agaaaaactc ccacaccgag acatcaaaac
     2041 tgcacggcgt tttttgggca acgacatctt cgcctgtaag cgggtagtgg ttttgcatcc
     2101 aaagcaggcg gttaacgata gccgtctgcc cgaccattac ccctttcggc ctgccggtgg
     2161 agccagaggt aaagatgata taagccgtgt ggtgcggttg tgaaagctgc agcggcgcac
     2221 tgccctgcgg tgtaagcggg gcgttatagc aaaggcgggt taaatctgga acatcggcaa
     2281 agcgcggcag ttgatcgtca gtggtgatta acagcgacgg acgcgcatct tccagcatca
     2341 ttttcaggcg atcgtccgga tagccggtat ccagcggtaa ccaggccgca ccagcctcaa
     2401 caattgcatg tagcgcgaga gtcaaaaaga ccgagcgcgg tagagccacc gccacgctgt
     2461 cgcccggttt aacgccgcgc tcacgcagca gattcgccag cgccaccacc tgctcgcgca
     2521 tttcccgata gctgaactgg taacgcgcat ctgccagcgc cggagcatcc ggtgtttttg
     2581 ccgcttgttc tgccaccagc gcgctcagcg tggtttctgg aatctcaatc tgagtggcgt
     2641 tgatctgcgc cagctgcgca tactcacctg gcagcataat atcgacatcg ccgcacaaca
     2701 gcgccggatc cgcggcgaac tgggcaatca gcattttcag gcgttcagcg tgttgaatta
     2761 acgttggctc atcgtaacgc tgtttattgg cgaggatttc aatactcaaa tctccgtgtt
     2821 catccgggaa cagggccagt tcaaggtcat taaccggacc ggttgccagg ggatgggttt
     2881 gcgcctgaac accaggaata tccagttggt aatcaaatac cttgatattg agtaccggac
     2941 cgaacagcgg ttcctctcct gccgctcgcc cactgtcacg gacaatttgt tcggcgtcgt
     3001 agcgttgatg gcggcgcatt tttttcagtt gtgctgccag tcgggttgcc agttgcggca
     3061 gcgtttcttg cgccgcaatg tgaataccca acggtaaaac gttgagcacg ggtccggtag
     3121 ccgtcagcgc cgccgagccc agtcgacgca taaagataaa tccggcagcg tagtccatgc
     3181 ggttgcacaa tcgccccagc cacaaggctg ccaacgcaag tgctaaatcg gtacgctgca
     3241 cacctgaaag ttgcgtagcc agctggcgga attccccgtc ggtaaattcc agtttcaggc
     3301 gcaaaatatc tgccgaagcg ctgcgccccg gtaaaggtgc cggagaaagt gacgcgggcg
     3361 gtggcagttg acgacgctgt tccgcccaga atgccgcatc acgctgccag gcttcacttt
     3421 cgcggtactg ctgatactct tccactacat cagcgaaagg cgtaaacggc gaagcaggcg
     3481 ttggttcgcc acgcagcaat gcgcagtaaa tattggcgat ctggcgtgta atggccggga
     3541 aactgaagcc atcgaccagc aaatggtgat aacgctgata ccagtaccag cggttatccg
     3601 ccacctgtat cagctgatga aagaccagtg gtttaccact atcgacgcgc agatcttgtt
     3661 gcaaatccgc ctgcattaat gcccgcgcag taccgtgcgg atcaatgttg gttcgcaggt
     3721 cgataatttc tggcagttcg aacgtctgcg catcatcgac ccactgccag acttcgccgt
     3781 tatcttccgt aaaacgcatc cgcaacgtat ctgcttgcgc tagtccggca accaccgcgc
     3841 gggccagtag tggcgcatca acctctccgg ttaactcaac gtaatgcgcc acgctccagg
     3901 cggagggtaa atccgacagt ttttctgcca tccagatgcc gggctgtgcg gcgaccaaag
     3961 gtaaatgctg gctcattgtg cctcctgcaa ctgggtgaaa ttcgccggtg tcagagtacg
     4021 ccagtgggct tccagccact gctggcagga cgcctgtgac tgcggctgac acacaacgtc
     4081 ccagcctgcc ggtaaggcgc attgttgcgg ccacagactg aattgcccct gcgcattgcg
     4141 caaaatgtaa aacgctccct gtggatcatc gaagggatta ctgaatgcca tattcaactc
     4201 ctgtcatgga aaagtggttg ccagaggtcg attagcccct gcatcaagcc accgcgccaa
     4261 caaagcgcat catgtccgcc gtcaacctga cgccagaaaa tggattcttt tagggggtgt
     4321 aattgcgcat acagcgcctg attggcctgc atgatcatcg gctcgcgaac acccgcttcc
     4381 agcacaatgc gcagaccttc ggcgctaact tcaccagttt ttagctgttc aagtaacatg
     4441 ccctcttggt gcccgccccg atgcggccac cagtacgaac ctgactggct taatacacag
     4501 ccaaagcgtt caggccagtg cagtccggca tacagcgcgg aaagcccacc aaaactctgt
     4561 ccggcgacca cggtgcgatc ggcgcgatcg ctaaaagggg caatagcttt cacctggggt
     4621 aataactctt gctgtactgc cagccagaaa tccgcattac acggcagttc gtgggcgcgg
     4681 tgcgtggtgt cgatagcgtc gatcaacaca tacacggcgg gcggaagttg ccgacgatgg
     4741 gtcagcgaag tcagcgcagg ccagacgggc atactctgcg cccaaaattc gccatcaagc
     4801 aaaactgcca gcgggcgttc ttctgctgtt gcatcgccga tggtaaaaat ccatacacgg
     4861 cgtgaatttt tcaaccgttc acttttccag ataatttctt tggcaggcgt ttctggcgct
     4921 tgcggacaat cccatcccgg ttgcagaggc gcttgcggca tttcgagtgc agaaacagcg
     4981 tgccctcgcc cgcctttcca gctttgtgga ttcagcggat cggctatcgc ctggggtaat
     5041 agttttcgcc agccttcgcg taattcgagg cgatcggggg atggtgcaga aaaaatgtca
     5101 tcgcgttcgg taggaataaa gcagtagctg ccgcgccagt tggcattgag ttgtgtcgtc
     5161 cactgccaaa catcggttcc tgcaattcgc tgcatcgacc ggggctggct gttctgatgg
     5221 tgatcggtca tgccagtgat atagacccat acgcgcttta tcgccgagtg gccttcagaa
     5281 ccttgtggat cacgccacca aaaagtgact tcaaacattt cgtcattcag acgttgccat
     5341 tccgggccat gtttcgactg ccaccagctc tcacttccta cttttaacgc cgtcacacca
     5401 taaccccatg tttactgtgc aattttttat tgattgcaga aatatattga taatattatt
     5461 gataactatt tgcatttgca atatcgtaat ggcgcgccgt gggaagcgcg gacattaatt
     5521 aatcagctgc actgcgtgtc tttcaggatc aaaggttttc gcggtagcgg gatgcgtcgt
     5581 gttgatgacg accatgcccg acagttgcaa ttcgtggcaa aaatgcagga ataaaacaat
     5641 gaacaagaag attcattccc tggccttgtt ggtcaatctg gggatttatg gggtagcaca
     5701 ggcacaagag ccgaccgata ctcctgtttc acatgacgat actattgttg ttaccgccgc
     5761 cgagcagaac ttgcaggcgc ccggcgtttc gaccattacc gcagatgaaa tccgcaaaaa
     5821 cccggttgcc cgcgatgtat cggagatcat tcgtaccatg cctggcgtta acctgaccgg
     5881 taattccacc agtggtcagc gtggtaataa ccgccagatt gatattcgcg gcatgggtcc
     5941 ggaaaacacg ctgattttga ttgacggcaa gccggtaagc agccgtaact ctgtgcgtca
     6001 gggctggcgt ggcgagcgcg atacccgtgg tgatacctcc tgggtgccgc ctgaaatgat
     6061 tgaacgtatt gaagttctac gtggtccggc agctgcgcgt tatggcaacg gcgcggcggg
     6121 cggcgtggtt aacatcatta ccaaaaaagg cagcggtgag tggcacggct cctgggatgc
     6181 ttatttcaat gcgccagaac ataaagagga aggtgccacc aaacgcacca acttcagcct
     6241 gaccggtccg ctgggcgacg aattcagctt ccgcttgtat ggcaacctcg acaaaaccca
     6301 ggctgacgcg tgggatatca accagggcca tcagtccgcg cgtgccggaa cgtatgccac
     6361 gacgttacca gccgggcgcg aaggggtgat caataaagat attaacggcg tggtgcgctg
     6421 ggacttcgcg cctctgcaat cactcgaact ggaagcgggc tacagccgcc agggtaacct
     6481 gtatgcgggt gatacgcaga acaccaactc tgacgcttac actcgctcga aatatggcga
     6541 tgaaaccaac cgcctgtatc gccagaacta ctcgctgacc tggaacggcg gctgggataa
     6601 cggcgtgacc accagcaact gggtgcagta cgaacacacc cgtaactcgc gtattccgga
     6661 aggtctggcg ggcggtaccg aagggaaatt taacgaaaaa gcggcacagg attttgtcga
     6721 tatcgatctt gatgacgtga tgctgcacag cgaagttaac ctgccgattg atttcctcgt
     6781 aaaccaaacg ctgacgctgg gtacagagtg gaatcagcaa cggatgaagg acttgagttc
     6841 caacacccag gcactcaccg gaacgaatac cggcggtgct attgatggtg tgagtgccac
     6901 cgaccgtagc ccatattcaa aagcagaaat tttctcgctg tttgccgaaa acaatatgga
     6961 gctgactgac agcaccatcg taacgccggg gctgcgtttc gatcatcaca gtattgtcgg
     7021 caataactgg agcccggcgc tgaacatatc gcaaggttta ggcgatgact tcacgctgaa
     7081 aatgggcatc gcccgcgcct ataaagcgcc gagcctgtac cagactaacc caaactacat
     7141 tctctacagt aaaggtcagg gctgctatgc cagcgcgggc ggctgctatc tgcaaggtaa
     7201 cgatgacctg aaagcagaaa ccagcatcaa caaggagatt ggtctggagt tcaaacgcga
     7261 cggttggctg gcgggcgtga cctggttccg taacgattat cgcaataaga ttgaagcggg
     7321 ctatgtagct gtagggaaaa acgcagtcgg caccgatctc tatcagtggg ataacgtgcc
     7381 gaaagcggtg gttgaaggtc tggaaggatc gttaaacgta ccggttagcg aaacggtgat
     7441 gtggaccaat aacatcactt atatgctgaa gagtgaaaac aaaaccacgg gcgaccgttt
     7501 gtcgatcatc ccggagtata cgttgaactc aacgctgagc tggcaggcac gggaagattt
     7561 gtcgatgcaa acgaccttca cctggtacgg caaacagcag ccgaagaagt acaactataa
     7621 aggtcagcca gcggttggac cggaaaccaa agaaatcagt ccgtacagca ttgttggcct
     7681 gagcgcgacc tgggatgtga ccaagaatgt cagtctgacc ggcggcgtgg acaacctgtt
     7741 cgacaaacgt ttgtggcgtg cgggtaatgc ccagaccacg ggcgatctgg caggagccaa
     7801 ctatatcgca ggtgccgggg cgtataccta taacgagccg ggacgtacgt ggtatatgag
     7861 cattaatact cacttctgaa gctaacgtca gattgttgac aaagtgcgcg tagttcatgc
     7921 cggatgcggc gtgaacgcct tatccggcct acaaaaatct tgccaattca atatattgca
     7981 ggaccacgta ggcctgataa gcgtagcgca tcaggcagtt ttgcgtttgt catcattctc
     8041 taatatggtt gacatgaaaa ctacgcatac ctccctcccc tttgccggac atacgctgca
     8101 ttttgttgag ttcgatccgg cgagttttcg cgagcaggat ttactctggc tgccgcacta
     8161 cgcacaactt caacacgctg gacgtaaacg taaaacagag catttagccg ggcggatcgc
     8221 tgcaatttat gcgctgcggg aatatggcta taaatgtgtg cctgcaatcg gcgagctacg
     8281 ccaacctgtg tggcctacgg gggtatacgg cagcattagt cactgtggga ctacggcatt
     8341 agccgtggta tctcgtcaac cgattggcat tgatatcgaa gagattttct ctgtacaaac
     8401 cgcaagagaa ttgacagaca acattattac accagcagaa cacgagcgac tcgcagaatg
     8461 cggtttaacc ttttctctgg cgctgacact ggcattttcc gccaaagaga gcgcatttaa
     8521 ggcatgtgaa agacaaactg atgcaggatt tctgcgctac caaatcagaa attgtcagca
     8581 tcaacagatg aatataagcg ggccgaatgg cgaccatatc gtgcagtggt tagtaagggg
     8641 taataatgtt attaccttgt gcctggcaga taaacacccg cacactgcag catgcgggtt
     8701 atctggcggg taattcaaag catttcccgt gcctgagctg caattccggc agcatcaaat
     8761 ccatgatgct gacgcaacca cccacgatcc gccgctgcgg catattctcc atccataatg
     8821 cctgcgcgtt ttaatgtgat ccccgttccg gcctctgcca acacttccgc gaccaggcta
     8881 ccaaggccgc cattgacgtt atgctcttca accgtcatca ctgctttgca tccttttaac
     8941 gctgccagca atgctttggt gtcgcatggg cgaatcgacg gtacgctgac aactgtagcc
     9001 gcgataccag actgcgctaa aagttctgcg gcatcgacca cttcatgaac ggtagagcct
     9061 gtggctacca gcgccagttc gctgccctcg cgcaaagtca ccacggcacc tggtacaaat
     9121 cggtagtcct catcgtggat ttccggcagg gctttaccgt ccatacggat ataaacaggc
     9181 ccctgatagc gaagagcata atcaatcacc tgacggcact cccgcggtga agacggggca
     9241 aagatttgaa tattgccgaa accacgcata accgcaatgt catcaatcgc atgatgcgtg
     9301 ctcgccagcg gtccataact cgccccggca ttcagaccga acaattttac gttggtaaag
     9361 ttgtagcaga catcaacctt gatttgctcg ttagcgcgag cgataagaaa cggcgcggca
     9421 ttgcaggtaa cagccacctt gccgcccagc gccagcccgg cagctgtacc aaccatgctc
     9481 tgttcggcaa tacccacatt caccagtcgg tcagggaatt gcttaataaa gggagcaatt
     9541 tttgccgtag acgttgaatc agccaccaca ggcaccaaat cgatcccctc atttacggca
     9601 tcgataaacg cctgaaccat cacatttgcc agatgttcac tgttacgcat ctttgagttc
     9661 ctccagtgcc tgttcaattt catcgccttt cggcacccgg tgatgccatt ccgcacgccc
     9721 ttgtataaag gaaatgcctg cccctttagt ggtgtgggca atcaccacat tcggtttgcc
     9781 ttcctgttta agctcttcaa gcgtcgcgac aaccgaagcc atatcattgc cctgacattc
     9841 agtaacctgc ataccgaatg ccagccattt ctctgccaga ggatcggtgt tcatgatttc
     9901 gcgcgttggc ccggctaatt gcagattatt tttgtcatta ataatgacca ggttatcaag
     9961 cccgtaatgc gccgccgcca gtgcagcttc ccagttactg ccctcagcca gctcaccatc
    10021 gccagtaatt aagaagatac gacgacggct ttgacttttt ttcgccgcca gcgcaagtcc
    10081 tacagccaca gggaaaccat gccccagtgc tccggtattc agttcaatac ctggcgtttt
    10141 ttgccgaacc ggatggccgg gtaagtgtga atttggctgc tgataagtgg aaagccattc
    10201 cagtgggaag aatcctgctt ccgccagcac gcagtagtaa catccaacag catggccttt
    10261 tgactgaatg tatatatccc ggtcatcgtc gtgaaggcga tccggtgcga cattgagaat
    10321 acgaaaatag agtgcggtca gtaattcaac ctgagagaga tcggccccgg tgtgtccacc
    10381 tgccgggcta ttggcattta agcgcacgat atggcggcgt accgcccgcg ctttacgctc
    10441 aagggtctgg atatcatagc tatagggatt catttaatac ctctgaattt attttcaaca
    10501 tggaatattt attccaccgg ggactaaaaa aaccagaaat cccagggcgt tgcgcggcaa
    10561 gacttacgct gctgcatcat actcaggaac attctgcctc cttacaccgt cagttacatg
    10621 tccgggtaat catcagttga cctgatatca tcttgaatat atattcaata atgattcttt
    10681 attcaattat gccgcctgtt ttttattttt gtccatcgct gattttaagg attggttaaa
    10741 gttagaactc catcacactt aactgtcttc ttttttcgcg tatgataaaa gcctctaaga
    10801 taagggcggt acgttaatga tttacgggga aatatatggc taagcaggat gaacagcggc
    10861 tactggtgaa gatcgccact ctttactatc ttgaggggcg aaaacagtct gacatcgccc
    10921 aacttctctc gctttctcag tcatttatat ccagagcgct aacccgttgc cagaaagaag
    10981 gcgtggttaa aatcagcgtt gtccagccgt caaatatctt tctcaatctg gaaaaaggca
    11041 ttgaagagcg ttacggcatt aaacaagcga ttgttgtcga taccgaagat gatgccagtg
    11101 atcacaccat taaacgcgcc atcggctctg ccgccgcgca ctatctggaa acgcgtttaa
    11161 ggccaaaaga tttcattggc gtctcttcgt ggagttctac gattcgcgcg atggtcgatg
    11221 aagttcacgc ccaaaactta aaagccagcg gcgttattca gctgctgggc ggcgtggggc
    11281 caaacggcaa tgtgcaggca actattttga cacagaccct ggcccagcat ctgaattgcg
    11341 aagcctggtt gcttccttct caaagcattg aaggttcggt agaagagaaa aaacgcctgg
    11401 tggcaagcca ggatgtggct gacgttatcg ccagatttga cgacgtcgat atcgccattg
    11461 tcggcatcgg tatccttgaa ccctcgcagt tgctaaaaac ctcgggcaac tattatcacg
    11521 aggatatgtt acaggtacta gcggatcgcg gtgctgtggg cgatatctgc ctgcactact
    11581 acgataaaca tggtcagccc gtgttgcagg acgatgaaga tccagtgatt ggtatggcac
    11641 tggataaaat caaaaaatgc ccgaatgtgg tggcactggc gggcggcaaa gacaaagttg
    11701 ccgccatcaa aggcgccatg cagggtggtt atattgatgt tttgatcact gatttcccca
    11761 ccgccagaat gctgattgcg gattaatcct ctcctccctt tcttctgccc gcctttgcga
    11821 aaaaatcttc tcgcaaaggt gattgcttaa aaagccttta atatcaataa actgaaagga
    11881 ttcaacaatc ctgtttctcg aggctttctc accctgtcac cacgcttcta agtgtgatag
    11941 ccagcacatt tgatgatttt ttctctagct caggaagaat aatctggcta aggtataaat
    12001 aaataatcag tatcgaatat atattcatgc cttaacacaa aatgtcacag cagggcctga
    12061 tgaagtaata acgtgaccat gaggaacgcc tcatctcctt ccacgccagg atgcaatgtg
    12121 actcaggaga ctacctatgt ttgcaggaaa taaagagttc gttattgcgt tggatgaggg
    12181 taccaccaat gcaaaagcca tcgcacttga tggtttcggt aacgtggtgg cgaagttttc
    12241 tcaaccactg gctattcaga cgccacgtga aggctgggtt gagcaatccg gggaagcgtt
    12301 aatctctgcc tcgcttgatg ttattgccca ggccatcaac cacgtggggg cagaaaatgt
    12361 agcggctctg gctatcagta atcagcgtga aacggctatc ggctggtatc gtcagagtgg
    12421 aaaaccactc aatgcggcga ttacctggca atgcacgcgc agtgccgagt tttgtgaaac
    12481 actgcgtcgc gagggcaaag agcagcaaat taaaacgact acgggtcttc ctatcgcccc
    12541 gctattttcc gcgtccaaga tgcgttggct actggaatct acacctgagg gtgtgcaact
    12601 tgccgaccag ggtgaaattt gtctcggcac cattgatgcc tggttgctat ggaacttgac
    12661 tgctggcgat tcattttgct gcgactactc taacgccgcg cgaactcaat tacttaacct
    12721 gaaaacaggc gagtgggatg aggaaatgct ggcgttgttt cacattccac gcgctgcatt
    12781 gccagaaatt aaaccttcca gtggcctgtt cggttatacc cgagggctta aaacaattcc
    12841 ggatggtatt cccgtcatgg cgatggtggg cgattctcac gccgctcttt ttggtcatgc
    12901 gttgggagaa gcgggatgtg tgaaagcgac ctatgggacc ggttcttccg tcatggcccc
    12961 cgtcaactct gctcagtgtg atatcgccac acttgccaca accattgcct ggcatgatgg
    13021 cgaaaatatt atttacggtc tggaaggaaa tatcccccac accggcgatg ccgtggcatg
    13081 gatggctgac agcaccggtt taagtgaact gacagacgcg gagctggccc tcgaactgaa
    13141 taccctgcca gcctcagtgg attcgactat gggtgtttat tttgttcctg ctctcactgg
    13201 cctgggcgcg ccatggtggg atgacagcgc tcgcggcgtg gtgtgtggct taagccgtgg
    13261 cgtaaagcgc gcgcatttga ttcgtgccgc actggaatca atcacttatc aaattgcaga
    13321 tgtagtggag gcaatgcaac agcatgatga ttttcactta tcggcgttaa tggtggatgg
    13381 cggcccgacc aaaaatgact ggttgatgca atatcaggcg gatctgctgg gttgcccggt
    13441 gatgtgcagt gatgtgccag agctttcagc cattggtgcg ggcctgctcg cccgcaaagc
    13501 gcttatcccc ggtaccgttg cagatttaaa agcgttatta actgaacaca gtgaatttaa
    13561 accggacatg gcgcgtcatc agcgactgca aaagagatgg caggagtggc gtcatgcggt
    13621 aaacagaaca ttatggaaac cggcatcgtc aatttgacga acaagactaa ccaacgtaag
    13681 gagaataccg gcccataaat aattcaggct ttacgttgtt tcaccgtacc cgacaataac
    13741 aacacagaga gaacattgtc atgaaattac gtttaacact gttaaccgct gcgaccctga
    13801 ctgctctttc tttttctgct catgcggtag aaaaaggaac cattatgatt atggtcaatt
    13861 cactggataa tccttattac gcctcggaag cgaaaggtgc cagtgaaaaa gcccagcaac
    13921 tgggatataa aacgaccatt ctttctcatg gtgaagatgt caaaaaacag aatgaactga
    13981 tcgatactgc aattggtaaa aaagttcagg gcattatttt agataatgcc gactccactg
    14041 ccagtgttgc agccattgaa aaagcaaaaa aagcaggtat tcccgttata ttaattaatc
    14101 gcgaaatacc tgtggatgat gttgcactgg tgcaaattac ccataataac ttccaggctg
    14161 gctcggaagt tgccaacgca tttgtcgaga aaatgggaga gaaaggaaaa tatgccgaac
    14221 tcacctgtaa tcttgctgat aataattgcg taactcgctc gaaatctttc caccaggtta
    14281 ttgaccagtt ccctgaaatg gtcagcgtgg cgaagcaaga tgccaaaggc acgttaattg
    14341 atggcaaacg aataatggac agtattctgc aagcccatcc cgatgttaaa ggggtgattt
    14401 gtggtaatgg tccggttgca ctgggagcta tcgcagcact gaaagccgcc aatcgcaatg
    14461 acgttattgt tgtcggcatt gatggcagta acgatgagcg cgatgccgtg aaagccgaat
    14521 cattgcaggc taccgtgatg ttacaagcac aagccattgc cgcgcagggt gttaccgatc
    14581 tggataatta cctgcaaaaa ggagttaaac cagccaaaca gcgggtgatg ttccgcggca
    14641 ttctgataac caaagataac gcagataaag tccaggattt caatatcaaa tcctgatccc
    14701 aggtcgttgc gccctcacaa tgagggcgca gaggagaata ttatggataa aaaagtctgg
    14761 ctggcgctgg caattctgag cctgggtgga tgtcgcatcg tctcgcagca ggaacttgcc
    14821 gatctcaaat ccccgcctaa tcctcatatg gcaaatatcg atcagacctg gcagaaaaac
    14881 atcgtgccgc aggtggtaga aaatgcgcgt ccggttgcgg agttaatggc ggcgctacag
    14941 gcagaaaaag atgtcgatgc tgcctgtaaa acgctgggct atcgttctca ggaagaaaac
    15001 ccgtgtattt tctacgttaa ggtcgaaggt agcatcacca atattgatgc gaaatcccgt
    15061 agcggaaaaa tgaccatcac agatatcagc ggcacaaata ttgtcgtgca gacggggcca
    15121 actcttcgcg gcacgcttct gcgagatgca tataaaggtg caagctatga gcattttaac
    15181 gatcaggttt tatttggtga atatggtcgt gctatcaatg agcaagccat caatatgatt
    15241 cagtcggcaa agcttaaaac cggggaaacg gttcaggttt atggcgtatt ttctgcatgg
    15301 gatattccgc aaactatccc ggatataacg cctgcgaaaa tagccagggc gggaggcgag
    15361 taatatgttg ccgcaagaaa ttgccccccc ccagactgat gaatcacctg taatcataga
    15421 aacgcatgac ttatcgcgta tttatccggg tgtggtggcg ttagataacg tgaattaccg
    15481 agtctatcgc aataaagtaa atgtgcttat tggtgaaaac ggtgcgggta aatccacaat
    15541 gatgaaaatg ctggcggggg ttgaaacacc ttcctcaggc aagatcattc ttgatggtaa
    15601 agaagtcacc ctaaattcta cccatcaggc cgaaaaacat ggaattagta tcatttttca
    15661 ggagctgaat ttattcccga atatgaatgt catggataat attttcatgg cgaatgaatt
    15721 ttttcagaaa gggaagatta acgaaaaata tcaatatgaa ttagccaaat ctctattaga
    15781 aagactggaa ctgaatgttg atccctatac ccaactggga gagctaggta ttggccatca
    15841 gcaactggtg gagattgccc gtgccctttc taaagatacc cgggtactga ttatggatga
    15901 accgacatcg gccctcagcc agtcggaagt aaaagtcctt ttcaatgtga tcgcacaact
    15961 gaagcgccgt ggtgtcacca tcatttatat ctcccatcgt ctggaagagt tgatggagat
    16021 tggcgatttc atcaccattt tccgtgatgg tcgctttatt agtgaacgcg ccgtgagcga
    16081 tgccagtatt ccatggatca tcgagcaaat ggtcggtgat aagaaaaaac atttcgatta
    16141 tcaaccagct acacaaggtg acactgtact ggcggtacaa gggttaacgg cgctgcatcc
    16201 cagcggtggt tacaaactca atgatgtgac attcagcctg cataaaggcg aagttatcgg
    16261 catttacggc ttgctgggcg caggacgtac tgaactattt aagggattgg tgggcctgat
    16321 gccctgtcag agtgggaaga tccagcttaa tggtgaaacc atcgacaaat gccatttcca
    16381 ggcgcggctc aaaaaggggc tggcgttggt gccagaagat cgccagggcg aaggcgtcgt
    16441 tcagatgatg tcgattcagt ccaatatgac gctatccgat ttcagcctgc aaggttttcg
    16501 ccgtgcctgg aaatggctga atccgcaaaa agagagcgcc agtgtgaaag agatgatcct
    16561 gcaactggcg atcaaagtca gcgatgccga actccctatt acctcactca gcggcggtaa
    16621 ccagcaaaaa gtggtacttg gcaaagcgtt gatgacccag ccacaggtgg tgtttcttga
    16681 tgaacccaca cgcggcattg atgttggcgc aaaaacagat gtctatcagc tggtgggaaa
    16741 aatggcacaa caggggctgg cagtcatgtt ctcttcttca gaactcgatg aagtcatggc
    16801 actggcagat cgcattctgg tgatggctga tggccgtatt accgctgatc tcccccgggg
    16861 cgaagtcacc cgagagaaac tgattgcggc ttcaacacct caagattaat caggctggaa
    16921 tttcttatga atcagaaata tatgatctat atgtacctgt tgaaggccag aacgtttatc
    16981 gctctgctat tagtgatcgc cttctttagc gtgatggtgc ctaacttcct gacagcctct
    17041 aacctgttga tcatgactca acacgttgcg attaccgggc tgctggcaat cggaatgacg
    17101 ctggtgatcc tgaccggcgg catcgatctt tccgtcggcg cggtagcggg gatctgcgga
    17161 atggttgccg gggctcttct aacaaacggc ctgccattgt ggagcggcaa tattattttc
    17221 ttcaacgtgc cggaagtgat cctctgcgtg gcggtatttg gcattttagt gggactggtg
    17281 aatggcgcgg taatcacccg ctttggtgtc gcgcccttta tctgcaccct cggtatgatg
    17341 tacgtcgctc gtggctctgc cctgctgttt aatgacggca gcacttatcc caatctcaac
    17401 ggcatggaaa cgctgggcaa cacgggtttc gccacccttg gttctggcac gtttttaggc
    17461 atttatctac caatctggct gatgattggc tttttgattt taggctactg gatcacgact
    17521 aaaacgccgc tcggtcgtta tatctatgcc attggtggca atgaatctgc cgcgcgactg
    17581 gcaggcgtcc ccatcgtaaa agttaaagtg ttcgtctatg cgttctccgg gttatgcgcc
    17641 gcatttgtcg gtttgattgt tgcctcgcag ctgcaaactg ctcacccaat gaccggcaat
    17701 atgttcgaaa tggatgctat tggcgccacg gttcttggtg gaactgcact ggcgggtggt
    17761 cggggacgtg tctctggctc gattatcggt gcctttgtca ttgtcttcct cgccgatggc
    17821 atggtgatga tgggtgtcag tgacttctgg caaatggtca ttaaaggcct cgttatcgtc
    17881 accgccgtgg tggtcgatca gttccagcaa aaattgcaaa acaaagtcat tttgatgcgt
    17941 cgccatgaag aaaagatggc cgccgcacct gccgtaaaac cgctttccag ttaattaaca
    18001 tcattccacc gggcattaaa ttgcccggct tatacagggg aaaaaatatg caacgtaatt
    18061 ttcagggtaa gactgtagtt attaccgggg catgccgggg aattggggcc gggatcgctg
    18121 aacgcttcgc ccgcgatggc gcaaatctgg tgatggtttc taacgctgaa cgcgtacatg
    18181 aaactgcaga gcaactgcgc caatgttatc aggctgacat tttgtcatta gaagtcgatg
    18241 tgacagatga agcgcaagta caggcactct atgaacaagc ggctgcacgt tttggcagca
    18301 tcgatgtttc cattcagaat gcaggcatta tcaccatcga ttattttgat cgaatgccgg
    18361 ctgctgattt cgaaaaagtg ctggcggtga acactacggc agtctggctc tgctgccggg
    18421 aagcagccaa atatatggtg aaacagaatc acggctgcct gatcaacacc tcttctggcc
    18481 agggacgtca ggggtttatc tataccccac actatgcagc cagcaaaatg ggtgtgatcg
    18541 gcattacgca aagcctggtg cacgagttag cgcagtggaa tatcactgtt aacgccttct
    18601 gcccgggtat tatcgaaagc gaaatgtggg actacaacga ccgcgtatgg ggagaaattc
    18661 tcagtaccga tgacaagcgt tatggcaaag gcgagcttat ggcggaatgg gtggaaggta
    18721 ttccgatgaa gcgtgccggt aaacctgaag atgttgccgg actggttgcc ttcctcgcct
    18781 ctgacgatgc gcgttatctc accggtcaaa ccatcaacat cgacggcggc ctgattatgt
    18841 cgtaatgccc ctgcgggcta ctaagagaga tatcaaaatg atcgcaaaag attttgctca
    18901 acaattgttt gatctccacg atcgcgtcgc ctttgtcact ggcgcaggta gcggtatcgg
    18961 acaaatgatc gctctggctt tagccagcgc aggcgcacga gtggtgtgtt ttgatctacg
    19021 ggaagatggc ggactcaaag agacggttaa tcatatcgaa gcacttggcg gacaagcctt
    19081 gtattacacg ggcgatgttc gggaattgag agatcttcgc gcagcagtcg ctctggcaaa
    19141 aacacatttt ggtcgtctgg atattgccgt aaacgccgct ggaatcgcta acgcaaaccc
    19201 ggcgctggag atggaaagcg agcaatggca acgcgttatc gatatcaacc tgactggtgt
    19261 gtggaattcc tgtaaggcgg aagctgagtt aatggtagag aacggagacg gttcgattat
    19321 aaatattgcg tcaatgtccg ggattattgt caatcgtggt ctggaacagg cccactacaa
    19381 cagttccaaa gccggcgtga ttcatttatc taaaagtctt gcgatggaat gggtgagtaa
    19441 ggggatccgc gtgaactcaa tcagcccagg atataccgcg acaccaatga atacacgacc
    19501 tgaaatggta catcagactc gggagtttga aagccagacg ccgattcaac ggatggcgaa
    19561 agtggaagag atggcgggtc cagcgctgtt ccttgccagc gatgcggcgt cgttctgcac
    19621 gggtgtggat ctggtggtcg atggtggctt tgtctgctgg taaaaatggt ttcgcccgca
    19681 gccatcactg accgcgggcg aaagtgtaaa gcaggtgcct taccaccctg acctgacaac
    19741 cggatatgcg gggattgctc cccgcacaac ggctacttct tcggttcgta agcgagaaca
    19801 gccttaaact caatattacg ttcctttacg gtaaactcac acagcgagtc tccgaccaga
    19861 agcgtaaatc ccagcaccgt caaacacagc actatgactg ccacaagggc atatttcgtc
    19921 agcatgttta tattgcctcc atgcgaagaa gggactacca tccaaattgt ctggtttgga
    19981 gtggcagccc cagggttgat agaaataact cctggggctt catctttcca gacctcaaag
    20041 ttaacctgaa accggaaagc ttcaggcacc cgccgttatc ttacccttcc tcaacaaaat
    20101 agctgtttat ttatacagta agtcctgttt cggacttctg ttggcaaaac tgatcattgc
    20161 ccttaaaacg acatcgcccg cagccatcac tgaccgcggg cgaaagtgta aagcaggtgc
    20221 cttaccaccc tgacctgaca accggatatg cggggattac tccccgcaca acggctactt
    20281 cttcggttcg taagcgagaa cagccttaaa ctcaatatta cgttccttca ccgtaaactc
    20341 acacagcgag tctccgacca gaagcgtaaa tcccagcacc gtcaaacaca gcactatgac
    20401 tgccgcaagg gcatatttcg tcagcatgtt tatattgcct ccatgcgaag aagggactac
    20461 catccaaatt gttcaggttt gggtaggtag ccccagggtt gatagaaata tcgtcctggg
    20521 gcttcatctt tccagacctc agagtaaacc tgaaaccgga aagcttcagg cacccgcagt
    20581 tatcttaccc ttcctcaaca aaatagctgt ttatttatac agtaaatcct gtttcggact
    20641 tctcactccc catttaatca actgaagctg aacccgtttt tttctgcatg cctcaatcgt
    20701 caaaattctt cgccgccagc cagctctgcc ataacttgtc acattgcaaa atgtagccaa
    20761 tttgcttcag tcaccatcac caaaaaaaga aacattccag aacttccgca tctcgcccag
    20821 ccgctcccac ttctatactg aatagaaaac gccaacataa gagaaaccta tgccattacc
    20881 cgattttcat gtttctgaac cttttaccct cggtattgaa ctggaaatgc aggtggttaa
    20941 tccgccgggc tatgacttaa gccaggactc atcaatgctg attgacacgg ttaaaaatca
    21001 gatcacggcc ggagaggtaa agcacgatat caccgaaagt atgctggagc tggcgacgga
    21061 tgtttgccgt gatatcaacc aggctgccgg gcaattttca gcgatgcaga aagtcgtatt
    21121 gcaggcagcg gcagaccatc atctggaaat ttgcggcggt ggcacgcatc cgtttcagaa
    21181 atggcagcgt caggaggtat gcgataacga acgctatcaa cgaacgctgg aaaactttgg
    21241 ctatctcatc cagcaggcga ccgtttttgg tcagcatgtc catgttggct gcgccagtgg
    21301 cgatgacgcc atttatttgc tgcacggctt gtcacggttt gtgccgcact ttatctccct
    21361 ttccgccgcg tcgccatata tgcaaggaac ggatacgcgt tttgcctctt cacgaccgaa
    21421 tattttttcc gcctttcccg ataatggccc gatgcagtgg gtcagtaact ggcaacaatt
    21481 tgaagccctg tttcgctgcc tgagttacac cacgatgatc gacagcatta aagatctgca
    21541 ctgggatatt cgccccagcc cccattttgg tacggtggaa gttcgggtga tggatacccc
    21601 gttaaccctt agccacgcgg taaatatggc gggattaatt caggctaccg cccactggtt
    21661 actgacggaa cgcccgttta aacatcagga gaaagattac ctgctgtata aattcaaccg
    21721 tttccaggcc tgtcgctatg ggctggaagg tgtcattacc gatccgcata ctggcgatcg
    21781 tcggtcacta acggaagcca ccttgcgttt actggaaaaa atcgcccctt ctgcacataa
    21841 aattggcgca tcgagcgcaa ttgaagcact gcaccgtcag gtcgtcagtg gtctgaatga
    21901 agcgcagcta atgcgtgatt tcgtcgccga tggtggctcg ctaattgggc tggtgaaaaa
    21961 gcattgtgag atctgggccg gagaataagt cgggaattgc cttacagaag aatatccctg
    22021 acaatggtgt tttaacttac atttaacaat gttatgaaac accctttaga aaccttgacc
    22081 accgcagcag gcattttgct gatggctttc ctctcttgcc tgctgctgcc cgcccccgca
    22141 ctggggctga cgctggcaca aaaactggtg accacgttcc atctgatgga tcttagccag
    22201 ctttacacgt tattgttttg tctgtggttt ttagtgctgg gcgctattga gtattttgtt
    22261 ctacgcttta tctggcgacg ctggttctcg ctggcggatt aaacgtcgat tatcgccgaa
    22321 cttcgcggca tactttgctt attctccttc gcctaaagga acatttatgg ataagcaatc
    22381 actgcacgaa acggcgaaac gcctggctct tgagttaccc tttgtcgagc tttgctggcc
    22441 ttttggcccg gagttcgatg tttttaaaat tggcggcaag atttttatgc tgtcgtcgga
    22501 gctgcgcggc gtccccttta ttaatctgaa gtccgatcca caaaaatccc tgctaaatca
    22561 gcaaatatac ccaagcatca agccagggta tcacatgaat aaaaagcact ggatttcggt
    22621 gtatcccggc gaggaaatct ccgaagcgtt acttcgcgat ctgatcaacg attcgtggaa
    22681 tctggtggtt gatggtctgg ctaaacgcga tcaaaaacga ctgcgtcctg actcaaccgt
    22741 aaatcaatag cgcatttttc tcgcttacca tttcatctcg atccttgtaa tctgctggca
    22801 cgcaaaatta ctttcacatg gagtctttat ggatatcatt tctgtcgcct taaagcgtca
    22861 ttccactaag gcatttgatg ccagcaaaaa acttaccccg gaacaggccg agcagatcaa
    22921 aactctactg caatacagcc catccagcac caactcccag ccgtggcatt ttattgttgc
    22981 cagcacggaa gaaggtaaag cgcgtgttgc caaatccgct gccgataatt acgtgttcaa
    23041 cgagcgtaaa atgcttgatg cctcgcacgt cgtggtgttc tgtgcaaaaa ccgcgatgga
    23101 cgatgcctgg ctgaagctgg ttgttgacca ggaagatgcc gatggccgct ttgccacgcc
    23161 ggaagcgaaa gccgcgaacg ataaaggtcg caagttcttc gccgatatgc accgtaaaga
    23221 tctgcatgat gatgcagagt ggatggcaaa acaggtttat ctcaacgtcg gtaactttct
    23281 gctgggcgtg gcggcgctgg gtctggacgc ggtgcccatc gaaggttttg acgccgccat
    23341 cctcgatgaa gaatttggtc tgaaagagaa aggctacacc agtctggtgg ttgttccggt
    23401 gggtcatcac agcgttgaag attttaacgc tacgctgccg aaatctcgtc tgccgcaaaa
    23461 cattacctta accgaagtgt aattctccct tgccgggcat ctgcccggct atttcccctc
    23521 agattctcct gatttgcata accctgtttc agccgtcatc ataggctgct gttgtataaa
    23581 ggagacgtta tgcaggattt aatatcccag gttgaagatt tagcgggtat tgagattgat
    23641 cacaccacct cgatggtgat gattttcggt attatttttc tgaccgccgt cgtggtgcat
    23701 atttttttgc actgggtggt actgcggacc ttcgaaaaac gtgccatcgc cagttcacgg
    23761 ctttggttgc aaatcattac ccagaataaa ctcttccacc gtttagcttt taccctgcag
    23821 gggattatcg tcaatattca ggcggtattc tggctacaaa aaggcaccga agcggcagat
    23881 attctgacta cctgcgcgca gttgtggatc atgatgtatg cgctgctttc agtcttctcg
    23941 ttgctggatg tgattttgaa tctggcgcag aaattcccgg cggcatctca gttaccgctg
    24001 aaagggattt ttcaggggat taaactgatc ggcgcgattc tggtcggcat tttgatgatc
    24061 tcgctgctga ttggtcagtc gccagcgatt ctgatcagtg gtcttggtgc aatggctgcc
    24121 gtgctaatgt tggtatttaa agatccgatt cttggtctgg tggcaggtat tcagctttcc
    24181 gcgaacgata tgctgaaact gggtgactgg ctggagatgc cgaaatacgg cgcggatggc
    24241 gcggtgatcg atattgggtt aaccaccgtc aaagtgcgta actgggacaa taccattacc
    24301 actattccca cctggtctct ggtttctgac tcctttaaaa actggagcgg gatgtcagct
    24361 tctggcgggc gacgtattaa acgcagtatc agtattgatg tcaccagtat tcgttttctt
    24421 gatgaagacg aaatgcaacg cctgaataaa gcgcatttgt taaagcctta tttaaccagc
    24481 cgccatcagg aaattaatga gtggaatcgc cagcaaggtt ctacggagtc ggtattaaac
    24541 ctgcgccgaa tgaccaatat tggaaccttt cgtgcctatc tgaacgaata tctgcggaat
    24601 catccgcgga ttcgcaaaga tatgacctta atggtacgcc aactggctcc tggtgataac
    24661 ggtttaccgc ttgagatcta tgcgtttacc aacaccgtgg tgtggctgga atatgaaagc
    24721 attcaggctg atatattcga tcacatattt gcgattgtcg aagagtttgg tctgcgactt
    24781 catcagtcgc caaccggcaa tgatattcgc tctctggcgg gtgcatttaa gcagtaatta
    24841 aaaaaaccgc tctcatcgaa tggatgagag cggctttcag attgttgaca tcattttgtc
    24901 ggatgcggcg tgaacgcctt atccgaccta cagaatcgtt acaaattgta ggcccgataa
    24961 gcttgcgcat cgggcaaatc agcctcacat cagcttaatt cactttccta cgcaatgttt
    25021 taaacgccac aaacaggaac acaatccaca ccggcagcag aatcgctgac aagcgcatat
    25081 catccatcgt gcacatcagc agcaaaatca tgccgaggaa ggcgatgcaa agatagttgc
    25141 cgaacggata gagcagcgcc ttaaattgtg tttcacgccc ctgacgtcgc atcgccgcgc
    25201 gaaaacgcag atgcgccagg cagatcataa tccagttcaa cagcagcgtt gctaccacca
    25261 gcgccatcag cagaccaaac gctttttgcg gcagcagata gttgattaac accaccagcg
    25321 aagtgatcgc tccggaaagc atcagcgagt taatcggcac gccgcgacgg ctgacgcgag
    25381 tcaaaaactt tggcgcatta ccctgcacag aaaggccaaa cagcatgcgg ctgttagagt
    25441 aaaccccgct gttatacacc gacagcgatg ccaccagaat gacgaagttc agcgcagaag
    25501 ctaccacgtt gctgtcgaga ttatggaaaa tcatcacaaa cgggctacta ttggatttca
    25561 cttccaccca cgggtagagc gccagtaaaa ccaccagtga accgatataa aacagcagga
    25621 tgcgatacac cacctgattc actgctttag ggatgctttt ttccggatcg cgcgcttcag
    25681 ccgcagtaat cccaatcagc tccagaccgc cgaaggagaa cataattacc gccagcgaca
    25741 aaatcagtcc attccagccg gtggcaaaga aaccgccgta gcgccagagg ttatcgatac
    25801 tggctttctc accgccgtgc ccagaaaaca gcagccacag gccaaagccg atcataccga
    25861 tgatcgccag cactttaatc agcgcaaacc agaactcggt ttcgccatat aagcgcacgt
    25921 tcaccaggtt aacggcgttg atgataataa agaaggcggc agcccaaatc cacgttggaa
    25981 catccgggaa ccagtactgc atatagatgc ccgcagcggt cagctctgcc attcccacca
    26041 gcacgaacat tacccagtag ttccagccag agaggaagcc cgcaaacggt ccccagtatt
    26101 tataggcaaa gtgggcaaat gaaccggata ccggctcttc gaccaccatc tcgccgagct
    26161 ggcgcataat caggaaagcg atgatcccgg cgacgccgta gcccagcaat acagccggac
    26221 ccgccatctg aatcgccggg ccaatgccaa gaaacagacc agtaccaatt gcgccaccca
    26281 gcgcaatcag ttgaatatga cggttatgta atccgcgatg aagcgtcggc tcttgattcg
    26341 acgcagtatc ttccgatacg gttgacgcgt ttttcacgcc tttcccctgt gtgtcttttt
    26401 tgttgagggg caccttttaa catttagtgc ccatcgtcgc aagacacaat ccacacggtt
    26461 aaacggggta tcctgctttt atttccgtac ccgatgtcgg tgcagccaca tcagcttata
    26521 cgccgccggg ataataaaca gcgacagcaa aggcgcggtg atcatgccgc caatcatcgg
    26581 cgcggcaatc cggctcatca cctctgaccc tgctcctgtt ccccacagaa tcggcagcag
    26641 accagcgata atcaccgcca ccgtcatcgc ttttgggcgc acgcgcagta ccgcgccgtg
    26701 atataacgcc tcatccagct tctgctcgct gaatgtttgc ggattattca acgacggctc
    26761 ggcctctatg gcgtgacgta aatacatcag catcaccacg ccaaattcgg cggcgacccc
    26821 ggcaagggca ataaaaccgg tgcccgtcgc cacggaaaga tgaaagccca tccaccacag
    26881 caaccagatg ccgcccacca gcgcaaacgg tacgctgctg ataatcagca acgcttcgcc
    26941 cacccgacgg aacgccagat acaacagcac gaagatgatc atcagcgtca tcggcaccat
    27001 cagtttcagc ttatggttgg cgcgctccag tagctcgaac tgcccggaga atgccacgct
    27061 ggtacccggt tttaactgca ctttttcagc tatcgctttt tgcagatcgt gaaccaccga
    27121 caccatgtca cgatcgcggg catcgatata aatccagctc gtcgggcgcg cattctcggt
    27181 tttcagcatc gacggtccgg tagagacttt aacgtcggcc acgtccgcca gagtgatttg
    27241 ctgcttcatc ggcgtgagga tcggcaactg gcgcagtgcc tgcgggctat cgcgccagct
    27301 ttgcggataa cgcagattaa ttggataacg agcaatccct tccaccgttt cgccaaccat
    27361 cgccccgccc accgcagaag tcacaaacaa ctgcacatcc gccaccgtca taccgtaacg
    27421 cgcggctttt tcacggttaa tctcaacgtt gatataacgc ccaccttcca gacgctcagc
    27481 aagcgcagaa gccacgcctg gcaccgttcg cgccacttct tcaatttgct ccgccatcgt
    27541 gtcgatatcc gccagcacag tgccggaaac tttaatgccg atagggcttt taatgccagt
    27601 cgagagcata tcgatacggt tacgaattgg cggcacccac agattcgcca gccccggcag
    27661 acgcacggtg ttatccagtt cctcaatgat tttgtccatc gtcatgccag gccgccactg
    27721 atcctgcggc ttaagctgga tagtcgtttc taccatctcc agtggagctg aatcggtggc
    27781 ggtttccgct ttcccggttt tgccaaatac ccgcgccact tccggtacgc tcataatcag
    27841 cttgtcgttt ttttgcagca tgctcgccgc ctctgctgcg gaaatccccg gcagcgtcga
    27901 tggcatatac aacaagtcgc cttcattgat ctgcggtaaa aattccccgc caactttatt
    27961 gagcggccag agaaccgtca gcaccgaaag cgctgccacc aacagcgtgg ttttcggcca
    28021 gtgcagtact ttcagcaaca gcggatgata aacacgaatc aaaaagcgat tgagcgggtt
    28081 actgctttcc ggcggaattt tgccacggat ccagtagccc atcaggatcg ggatcactac
    28141 gatcgccagt agcgccgcgc ccgccatcgc ataggttttg gtgaacgcca gcgggccaaa
    28201 cagacgacct tcctgccctt ccagggtgaa gatcgggata aacgacagcg tgataatcag
    28261 cagactgata aacagcgccg gccccacttc aacagatgca tcggtgatca cctgccagcg
    28321 cgttttatta tccagcgtgg cgtcaggatg ctggtgctgc cactcttcca gccgtttatg
    28381 cgcattctcg atcatgacga tagcggcatc gaccatcgcc ccgacggcaa tcgcaatgcc
    28441 acccaacgac ataatattgg cgttcagtcc ctgaaagtgc atgacaataa aagcaataca
    28501 caaccccagc ggcaacgaaa taatcgccac cagcgccgag cgcacatgcc agagaaacag
    28561 cgcacagact accgccacca caataaactc ttccagcaac ttgccgctga ggttgtcaat
    28621 ggcgcggtca atgagctggc tgcgatcgta tgttgtaact atctccacgc cttccggcag
    28681 actgcttttc agcgtttcca gtttgtcctt cacagcggcg atcacttcac gggcgttttt
    28741 gccggaacgc aggatcacca ccccgcccgc cacttcgcct tcgccgttca gttcggcaat
    28801 gccccggcgc atctccgggc caacctggac cttcgcaaca tcacgcagat aaacgggcac
    28861 gccattttca ctggctttta aaacgatgtg attaaagtcg tcgagcgttt gcagatagcc
    28921 gctggcgcgc accatatatt ccgcttccgc cagttctatc gacgaaccgc ccgcttcctg
    28981 gtttgaagca tccagcgcgc tttttacgtc ggcgagactg atgccatact gcgccaggcg
    29041 ctgaggatcg ctaaccacct gatactcttt caccacaccg cccaccgacg ccacttccgc
    29101 aacgtcaggg atggttttta gctcatattt gagaaaccag tcctgcaatg agcgtaaatc
    29161 ggccagatcg tgcttaccgc tgcgatccac cagtgcatat tcatagatcc agccaacacc
    29221 cgtggcatct ggccccagct cggcgctgac tcccgcaggc agcttaccct gtacctggtt
    29281 gaggtactcc agcacccgcg agcgcgccca gtacggatcg gtgccatctt cgaaaatgac
    29341 atacacataa gagtcgccaa actgcgagaa accgcgcaca gtcttcgcgc caggcaccga
    29401 caacatggtg gtggttagcg gataagtcac ctgattttca acgatttgcg gtgcctgacc
    29461 gggatagctg gttttaataa tcacctgcac atcggaaaga tccggcagtg catccactgg
    29521 cgtgttaatg atggtccagg tgccccagat actcagaaac aacgcgccca tcagcaccag
    29581 aaaacggttc gccaccgagc gacgaataat ccattcaatc attggctatt ccctcaatgc
    29641 gcatgggtag cactttcaga gcgcatccgc tccagtgcgc cagaaatatt ggcttcagaa
    29701 tcaatcagga acaggccgct ggaaaccacc ttttcacctt ccgccagacc agagcgtaac
    29761 gcggtgacgc cttgcgatgc ctggaaaacg gcaacgcgtt tcggtacaaa gcgcccgtca
    29821 gcatcaacgg taatcacccg ctgttcgttg ccggtatcaa tcagcgcctg tgacggaatg
    29881 agcagcatcg gttcgctggc ggtattgagt tgcaacccgg cgttcatgcc cggttttagc
    29941 gcctcgtcgg cgttgtcgat ttccagacgc aactgcagcg tgcgggtcgc ggcatccacg
    30001 ccgggtagca gggtccattt gcgaatggtg agtgttttat caggtcgcgc cggaacggtg
    30061 agcgtaaact gcgaggcatc tttcaccagc caggcgatgg actccgggat cgcagcagtg
    30121 acccacaccg ggtccatacc ctgaattttc gcgaccacgt tatctttggc gatattcatt
    30181 cccgcgcgca gatcaaacgc ggtgatcacg ccatcaatgg gcgctttgag cgtaaagcga
    30241 gtctggattt tttgcgtggc gatcaggcgg cgaatatcag cctccggcat tcccgccagt
    30301 cgcagtcgct caagaatgcc ttcagtctgg gtcgccgtac cgccggtttc gcgcagcagt
    30361 aaatactcac tctgcgcttc cacccagtcg ggaatggtca ggtcgagaag cggcgcgccc
    30421 ttttgcactt tatcgcccac ggtaagcgga tacaccttgt cgataaaccc ggcggcgcgg
    30481 gcctgcacaa tggcatactg atactcgttg taactgacat tcgccgggaa actctgggaa
    30541 aaagtcagcg gcccgcgcgt gacggtcgcc gttttcaccc ccagattctg cgtctgagtc
    30601 gggtcaatgc gcacaccaga cgcagaactc tcttcatcgg catatttcgg caccagatcc
    30661 atatccataa acggcgattt ccctggttta tcgaaccgcg tattgggata catcgggtcg
    30721 taccagaata agactttacg ttctgcggtc gacgtttttt ctgcgggcgg ttcctccttt
    30781 gcaaaccagg taaaacctgc cgcagaaata ataccgcccg cgatcatgct gccgataata
    30841 agcgcgattt ttttcatctc attaaacccg gattactggc tgactttaat atcctgtaat
    30901 aaagaaagat tgccctgctg gacaaaatta aacgctactt tatcgccggt tttaatttcg
    30961 ctcattttcg tctgcggggt gatggtaaag cgcatagtca tctccggcca gttcacggca
    31021 gcaatcggat cgtgatggat ggtgattttt ttgctttcca gatcaacacc ttttaccacg
    31081 ccagtggcgc taataacctg tggttgtgct tcgctcatgg tttcatgatg atgttcgtta
    31141 gcctgggcat taaagccaat aacggtaaac agactgaaca ttgcgacttg cagtgctttt
    31201 ttcatttatt ctctcctgga gttaaaaatt attgctgcca accgccccct aaggcggtat
    31261 ataaagaaat ttcgttaacc tgacgggcat aattcaggtc aagtaaagtt tgtcgggttg
    31321 caaataaaga acgttcagca tccagcactt ccagataact gactgcgccg tgctgatata
    31381 atgcccgcgc ccgttgcagg gtaatttgca gcgacgcaag ataacgctgc tgggcgctga
    31441 tttgatcgtt caggctttga cgtaatgcca gcgcatctgc cacttcttta aaggcgttct
    31501 ggattttctg ttcataattc accaccgact gctgctggcg aatttcggtg atatccagat
    31561 tggcctggtt gcgtccggca ttaaaaatgg ggatctcaat tttaggaata aaattccaca
    31621 tcccgctgct ggcgttaaat aatgacgaca gatcgctgct ggcggttgat attccgctgg
    31681 tcaggctgat agacgggaaa aatgccgcac gcgcagcacc aatattggca ttagccgcca
    31741 ttaacgcgtg ttcagcttcc ataatatcag ggcgctgcaa taagatttgc gacgacaagc
    31801 ccgccggtaa tttaacgctt tgcaggctgt cgctgtttac tgtctgcgct tgcggcagct
    31861 tgccgtagct tcccaataac agttgcaatg cattattcgc ctgcgccagt tccccctgac
    31921 gtttagcgat gtcgctgcgg gtactttcta tcaccccgcg agcctgttcc agcgccagaa
    31981 cattgctgct accggtcaac agttgttttt cgacaaacgc atatgactgc tgataattac
    32041 gcagcgtttc ttcggctatt tgcaattgcg catacgccag ttgctgattg aaatagcttt
    32101 gcgcgacatt agaaaccaac agaatatgca ccgcgcgctg agcttcctca gtggctaaat
    32161 aattttggcg ctcggcttcg ctcatgttct ttaagcgacc gaaaaaatcg agatcaaagc
    32221 tggcgttaag gccagtcgat aactcccgcg tcgtggctga atcgccttta agattgccgc
    32281 tccagctgcc gctgccctcg ccattgagct gtgggtagcg gtcggcatcg gtcagacgat
    32341 attgcgcccg cgcttcctgc actttcagcg ccgccatgcg caaatcccgg ttattcacca
    32401 acgcctcgct aatcagcgtc ttcacctgat tatcaacaaa aaaggtgcgc cagcccgcgt
    32461 tctggtagtt atctgctgcg ttaaccaggc cgttctggct gagtgagaac tgctgcggca
    32521 cgggcattgc cggacgctga taatccggtg ccagtgaaca accggttagc gcaagggcca
    32581 cacaaaatgg cagaagttta caaggagaca taggctcata atttctggtg attttatgct
    32641 gccaacttta ctcgccaggc tctgattttc cggtgacagg aaaatgacaa aattgtcatt
    32701 ttgccaataa gcgattgcca tctgatcccg ctactctaga attgcccggg caacatgcgg
    32761 aggaaatatg aaactgttga ttgtcgaaga tgaaaagaaa accggagaat acttgaccaa
    32821 agggttaacc gaagccggtt ttgtggtcga tttggccgac aacgggctga atggctacca
    32881 tctggcgatg accggtgatt atgatctgat aatcctcgat attatgctgc cggacgtgaa
    32941 cggctgggat atcgtgcgca tgttgcgttc cgccaataag gggatgccga ttctgttgct
    33001 taccgcgctt ggcaccattg aacatcgcgt caaggggctg gagttggggg cggatgacta
    33061 tctggtgaag ccgttcgctt ttgctgaact gctggcgcgg gtgcgcactc tactgcggcg
    33121 cggagcggcg gtaattatcg aaagtcagtt tcaggttgcc gatctgatgg tcgatctcgt
    33181 cagccgcaaa gtcacccgca gcggcacgcg catcactctg accagtaaag aatttactct
    33241 gctggagttt ttcctccgcc atcagggcga agtgctgccc cgctcgctta tcgcctcgca
    33301 ggtatgggac atgaattttg acagcgatac caacgccatt gatgtggcgg tgaagcggct
    33361 gcgcggcaaa atcgacaacg actttgagcc aaagttgatt cagaccgtgc gcggcgtggg
    33421 ttacatgcta gaggtgccgg atggtcagta agccatttca gcgcccgttt tcgctggcaa
    33481 cccgcctgac cttttttatc agcctcgcca ccatcgcggc gtttttcgcc tttgcatgga
    33541 tcatgatcca ctcggtaaaa gtgcattttg ccgagcagga tattaatgat ttaaaggaga
    33601 ttagcgccac ccttgaacgg gtacttaatc accctgacga aacgcaagcc cgacgcttaa
    33661 tgacgctgga agatatcgtc agtggttatt ccaatgtgtt gatctccctg gcaaatagcc
    33721 acggtaaaac ggtgtatcac tcccccggtg cgccggatat ccgcgagttt acgcgtgacg
    33781 ccatacccga taaagacgcg caggctggcg aggtgtatct cctttccggc ccgacgatga
    33841 tgatgccagg gcacggtcac gggcatatgg aacacagcaa ctggcggatg attaacttgc
    33901 cggttggccc gctggttgac ggcaaaccga tttatacgct ctacatcgcg ctttcgatcg
    33961 attttcatct tcattacatc aatgatttga tgaataaact tattatgacc gcatcggtaa
    34021 tcagcatcct gatcgtcttt atcgtgctgt tggcggtaca taaaggtcac gcgccgatcc
    34081 gcagcgtcag ccgtcaaatc cagaatatca cctcgaaaga tctcgacgtt cgccttgacc
    34141 cgcagaccgt gcccattgag ctggaacagc tggtactgtc gttcaaccat atgatcgagc
    34201 gtattgagga tgtctttacc cgacagtcca atttctcagc ggatatcgcc cacgaaattc
    34261 gcacacctat tactaatctc attacgcaaa cggaaatcgc cctcagccag tcgcgcagcc
    34321 agaaggagct ggaagatgtg ctctactcta atctcgaaga actgacgcga atggcgaaaa
    34381 tggtcagcga tatgctgttt ctcgctcagg ccgataacaa ccagctaatc cccgaaaaga
    34441 aaatgctcaa cctggcggat gaagtcggca aagtgttcga ttttttcgag gcgttagcag
    34501 aagatcgcgg cgtggagctg cggtttgttg gcgacgagtg tcaggttgcg ggcgatccgc
    34561 tgatgctgcg tcgggcgtta agcaacctgc tttctaatgc cctgcgttat acgccaaccg
    34621 gagagacaat tgttgtgcgc tgccagacgg tcgatcacct ggtgcaagtt accgtcgaaa
    34681 accccggtac gcccattgcg cccgaacact taccgcgatt gtttgaccgt ttctaccgcg
    34741 ttgatccttc ccgccagcga aaaggcgaag gtagcggcat tggcctggcg atagtgaaat
    34801 cgattgttgt cgcgcataaa ggcacagttg cggtaacgtc agatgctcgg gggacaaggt
    34861 ttgttatcat attacccgct taatccttca gcaaacggca acttttataa ccagtgtaaa
    34921 aataacatgc cgcaatagta atacctatta atgataaaaa gctgtcacaa ttcataaaaa
    34981 accttaatat acgccaccct aaacataacc agcgttaatg taaggttttt gtgtggactg
    35041 gcttcttgat gtttttgcta cctggctcta cggcttaaaa gtaatcgcga taacgttagc
    35101 ggtcattatg ttcatcagcg ggctggacga tttttttatt gatgtcgtct actgggtacg
    35161 ccgcattaaa cgcaagttga gtgtttatcg ccgctacccg cgaatgagtt accgcgaact
    35221 gtataaacca gatgaaaaac cgttagcgat tatggttccg gcgtggaatg aaacgggcgt
    35281 catcggcaat atggccgagc tggcggcgac cacgctcgac tacgaaaact atcatatctt
    35341 tgttggcacc taccccaacg accccgatac tcagcgtgat gttgacgaag tgtgcgctcg
    35401 cttcccgaac gtgcataagg tagtctgcgc gcgtcctggc cccaccagca aagccgactg
    35461 tctgaacaac gtgctggacg ccatcaccca atttgaacgt agcgccaatt tcgcttttgc
    35521 tggttttatt ctgcatgacg ccgaagatgt gatttcacca atggaattgc gtctgttcaa
    35581 ctatctggtc gagcgtaaag atctgattca gatcccagtg tatccgttcg aacgcgaatg
    35641 gacgcacttc accagcatga cctacattga tgagttttca gaactgcatg gcaaagatgt
    35701 tccggtgcgt gaagccctcg ccggacaggt gcccagcgca ggagtcggca cctgtttcag
    35761 ccgccgcgcc gtgaccgcac tgttagctga cggtgacggt attgctttcg acgtgcagag
    35821 tctgactgaa gattacgaca ttggcttccg cctgaaagag aaaggtatga cggaaatttt
    35881 tgtccgtttt ccggtggtgg acgaagccaa agaacgcgag cagcgtaaat ttttacagca
    35941 tgcgcggacg tcaaacatga tctgtgtgcg cgaatatttc cccgatacct tttcgactgc
    36001 ggttcggcaa aaatctcgct ggatcatcgg cattgttttc cagggcttta aaacccacaa
    36061 atggacctcc agcctgacgc tgaactactt tctctggcgc gaccgcaaag gggcaatcag
    36121 taactttgtc agcttcctcg cgatgctggt gatgatccag cttttgctgt tgctggcgta
    36181 tgaaagtttg tggcccgatg cctggcattt cctttctatt ttcagcggca gcgcatggtt
    36241 aatgactctg ctgtggctaa actttggctt gatgattaac cgcatcgtgc agcgggtgat
    36301 tttcgttact ggctactacg gcctgacgca ggggctgcta tctgtcctgc gtcttttctg
    36361 gggcaacctg attaacttca tggccaactg gcgcgcgtta aaacaggtac ttcaacacgg
    36421 cgatccacgt cgtgtcgcgt gggataaaac aacgcatgac ttccccagcg tgactggcga
    36481 tacccgctcg ttgcgtccgt taggtcaaat cctgctggaa aatcaggtca tcactgaaga
    36541 acaactcgat acagcactgc gtaatcgcgt cgaaggtcta cgcctgggcg gttcaatgct
    36601 gatgcagggg ctgattagcg ccgagcaact ggcacaggcg ctggcagagc aaaacggcgt
    36661 ggcgtgggaa tccatcgatg cctggcagat cccttcctcg ctgattgccg aaatgccggc
    36721 ctccgtggcg ttgcattatg cggtactgcc gctgcgtctg gacaatgatg agttaattgt
    36781 cggcagtgaa gatggtattg acccggtttc gctggcggcc ctgacgcgta aagtcggacg
    36841 caaagtgcgt tacgtcattg ttctgcgagg acaaattgtc accggattac gccactggta
    36901 tgcacgccga cgcggtcacg atccgcgggc aatgttgtac aatgcagttc agcatcagtg
    36961 gctcacggaa cagcaggccg gtgaaatctg gcggcaatat gtgccgcatc agttcctgtt
    37021 cgcagaaata ctgaccacgc tcggtcatat taatcgttca gcaattaacg tgttgttatt
    37081 gcgccatgaa cgcagttctc tgccgctcgg caagtttttg gtcaccgaag gcgttattag
    37141 ccaggaaacg ttggatcgcg tcctgacaat tcaacgcgaa ttacaagttt cgatgcaatc
    37201 actattactc aaagcaggtt taaacactga acaggttgca caactggagt ccgaaaatga
    37261 aggagaataa ccttaatcgc gtcatcggat ggtctggttt actgctgaca tctttattga
    37321 gtaccagcgc actcgcagac aatatcggca ccagcgcaga agagctgggg ctgagcgatt
    37381 atcgccattt tgttatttat ccccgtctcg ataaggcgct gaaggcacag aaaaataacg
    37441 acgaagcaac cgccatccgc gaatttgaat atatacacca gcaggtgccg gataatattc
    37501 cgctgacttt ataccttgcg gaagcctatc gccattttgg tcatgatgac cgggcgcggc
    37561 tgttgcttga ggatcaactg aaacgtcacc ctggagatga ccggcttgag cgcagtctgg
    37621 cggctattcc agttgaagtg aaaagcgtta cgactgttga agaactgctt gcccagcaaa
    37681 aagcgtgcga tgctgcgccg accctgcgtt gtcgcagtga agtcgggcag aatgccctgc
    37741 ggctggcaca attacctgtc gccagagcgc aacttaacga tgcgacgttt gctgcatcgc
    37801 cggaaggaaa aacgttgcga accgatctgc tgcaacgggc aatctacctg aaacaatggt
    37861 cccaggcaga tacgctatat aatgaagcac gccagcagaa cacattaagc gcggcagaac
    37921 gccgtcagtg gtttgacgtg cttcttgccg cgcagctgga tgatcggatc ctggcgctgc
    37981 aatcacaggg gatcttcacc gatcctcagt catatattac ttatgcgacc gcgctggctt
    38041 atcgtggcga aaaagcacgc ctccagcatt atctcattga aaataagccg ctgtttacca
    38101 cggacgcaca agagaaaagt tggctctatc tgttatctaa atacagcgcc aaccccgttc
    38161 aggcgttggc gaattatacg gtgcagtttg ccgataaccg ccagtatgtt gttggcgcga
    38221 cgctaccagt gctgttaaaa gaaggtcagt acgacgcagc gcaaaaactg ctcgccaccc
    38281 tccccgccaa tgaaatgctt gaggagcgtt atgccgttag cgtagcaacc cgtaacaagg
    38341 ctgaagctct gcgtctggca cgattgctgt atcagcaaga accggcaagt cttacccgtc
    38401 tggatcaact gacctggcaa ctgatgcaga acgggcagtc acgcgaagct gccgatttat
    38461 tgctgcaacg ctatcctttt cagggcgatg cgcgtgtcag ccagacgtta atggcgcgac
    38521 tggcgtctct gctggaaagt catccttacc tggcaacgcc ggcgaaggtg gcaattttat
    38581 cgaaaccttt accgctggcg gagcaacgtc agtggcaaag tcagttgccg ggtattgctg
    38641 ataattgccc ggcaatagtt cgcttgctgg gcgatatgtc gccttcttac gatgctgccg
    38701 cctggaaccg tctggcaaag tgttatcggg acacgctacc cggtgtggcg ttgtatgcat
    38761 ggcttcaggc cgaacaacga caaccggacg cctggcaaca tcgtgcggta gcctatcagg
    38821 cgtatcaggt tgaggactat gccaccgcac tgacagcctg gcagaaaatc agtcttcacg
    38881 acatgagcaa tgaggatctg cttgctgccg ccaataccgc ccaggcggca ggaaatggcg
    38941 cggctcgcga tcgctggtta caacaggcag aacaacgtgg actgggaaac aatgccctct
    39001 actggtggct gcatgcgcaa cgttacattc caggtcagcc ggaactcgca ctgaacgatc
    39061 tcacgcgctc aatcaatatt gcgccttctg ccaacgctta cgttgcgcgg gcaacaattt
    39121 atcgccaacg tcataatatc ccggcggcgg tgagtgattt gcgcgccgcg ctggaactgg
    39181 aaccgaataa tagcaacacc caggcagcgc ttggttacgc cttgtgggat agcggtgata
    39241 tcgcacagtc gcgggaaatg ctcgaacagg cgcataaagg gctaccggac gatccggcac
    39301 ttatccgaca actggcctac gtgaaccaac gtctggatga catgcctgcg acgcagcact
    39361 acgcccgact ggtgattgat gacattgata atcaggcgct gataacccca ctgaccccag
    39421 agcaaaatca gcaacgcttc aatttccgcc gtctgcatga ggaggtcggt cgccgctggt
    39481 cgttcagttt cgattcttct atcggcttgc gttccggcgc aatgagtacc gctaacaata
    39541 atgtcggcgg cgcagcgcca gggaaaagct atcgtagcta cgggcaactg gaagccgagt
    39601 accgcctcgg acgcaatatg ctgctggaag gcgacctgct ctcagtttat agccgcgtct
    39661 ttgccgatac cggtgaaaac ggggtgatga tgccggtgaa aaatccgatg tccggcaccg
    39721 gtctgcgctg gaagccactg cgcgatcaga tctttttcct cgccgtcgaa cagcagttgc
    39781 cgctgaacgg acaaaatggc gcatccgata ccatgctgcg cgccagcgcc tcattcttta
    39841 atggcggcaa atacagcgac gaatggcacc cgaacggttc aggctggttt gcccaaaacc
    39901 tgtacctcga tgcggcgcaa tatatccgcc aggatattca ggcgtggacg gcagattatc
    39961 gcgtcagctg gcatcagaag gtggcgaacg ggcagactat tgagccttat gctcacgttc
    40021 aggacaacgg ctatcgtgat aaaggcactc agggcgcgca gcttggcggt gtcggggtcc
    40081 gctggaatat ctggaccggc gagacgcact acgacgcctg gccgcacaaa gtcagtctcg
    40141 gcgtcgaata tcaacatacc tttaaggcga ttaatcaacg taacggagag cgcaacaacg
    40201 cgtttctcac cattggagtg cactggtaaa tgcgtaagtt cattttcgta ttgctgacac
    40261 tgcttttggt cagccctttt tcctttgcga tgaaaggtat tatctggcaa ccacaaaacc
    40321 gtgatagtca ggttaccgat acccagtggc aggggctgat gagtcagtta cgtttgcaag
    40381 gcttcgatac actggttttg caatggaccc gttacggcga tgcattcacc cagccagaac
    40441 agcgcgcgtt attgtttaag cgtgctacag ctgcgcaaca ggctggcctg aagctgattg
    40501 tcgggctgaa cgccgatccg gaatttttta tgcaccagaa acagtcgtcc gcagcgctgg
    40561 aaagctatct taatcgcctg ctggctgccg atctccagca agccagatta tggagcgccg
    40621 tgcctggcgt aacgccggat ggctggtaca tcagcgcgga aattgacgac ctgaactggc
    40681 gcagcgaagc cgcccgtcag cctttgctaa catggttaaa caacgcgcag cggttgatta
    40741 gcgatgtttc agcaaaaccg gtttatatca gtattttttt cgccggaaac atgtcgccag
    40801 atggctatcg ccaactgctg gaacaagtta aagcaaccgg tgttaatgtc tgggtacagg
    40861 atggcagcgg cgtggataaa ctgaccgctg aacagcgtga acgttatcta caggccagcg
    40921 ccgattgcca aagttccgcc ccagcaagcg gcattgttta tgaactgttt gtcgctggta
    40981 aaggtaaaac gtttacagcg aaaccgaaac cggatgcaga gatcgcctcg ctgttagcga
    41041 aacgttcctc ttgcggtaaa gacacgctct atttctctct gcgctatttg cccgtcgcgc
    41101 agagtatcct tgagtattaa tgattaaagg gagcaactta gcttgctcct ttccttttca
    41161 ctttcctaat caaaatcctg gcaagatgaa ttatttagca gaatatctgt tttcatttta
    41221 ttcgtctgac gtgttccaat tatttagcaa aaccgcgaca acaaagtgat ggtgtaattt
    41281 gtaaaaggga acaaataaat ggctcgccct gcaggattcg aacctgtagc ccacggctta
    41341 gaaactccag gaacgacatt ttaagtcaac aaattaccgc gccatctctg cgttcacacg
    41401 tcccactacc tcaaaatatg taaaaccttg caagccattg cgaggcctta tgtgtctcag
    41461 ttttgttcct cttttttata ctaaaaaaca cagcaattga ggataaacct catgctatta
    41521 tcgctaatat gcatctaaag gcatggcact tgaatagata aaaactccac aaagaaaaaa
    41581 ataattagcc cataaaacca caatgcaaaa cacaaacaga caattaaact aaaaaactga
    41641 cagtgcattg tgacaaaaat tcaatgttaa acaaaatata aacagtgggg caatatacaa
    41701 ttgactcatt aagttagata taaaaaatac atactcaatc attaaaacga ttgaatggag
    41761 accttttatg cgggcgaaac ttctgggaat agtcctgaca acccctattg cgatcagctc
    41821 ttttgcttct accgagactt tatcgtttac tcctgacaac ataaatgcgg acattagtct
    41881 tggaactctg agcggaaaaa caaaagagcg tgtttatctg gccgaagaag gaggccgaaa
    41941 agtcagtcaa cttgactgga aattcaataa cgctgcaatt attaaagggg caattaattg
    42001 ggatttgatg ccccagatat ctatcggggc tgctggctgg acaacactcg gcagccgagg
    42061 tggcaatatg gtcgatcagg actggatgga ttccagtaac cccggaacct ggacggatga
    42121 aagtagacac cctgatacac aactcaatta tgccaacgaa tttgatctga atatcaaagg
    42181 ctggctcctc aacgaaccca attaccgcct gggactcatg gccggatatc aggaaagccg
    42241 ttatagcttt acagccagag gtggttccta tatctacagt tctgaggagg gattcagaga
    42301 tgatatcggc tccttcccga atggagaaag agcaatcggc tacaaacaac gttttaaaat
    42361 gccctacatt ggcttgactg gaagttatcg ttatgaagat tttgagctag gtggcacatt
    42421 taaatacagc ggctgggtgg aagcatctga taacgatgag cactatgacc caggaaaaag
    42481 aatcacttat cgcagtaaag tcaaagacca aaattactat tctgttgcag tcaatgcagg
    42541 ttattacgta acacctaacg caaaagttta tattgaaggc gcatggaatc gggttacgaa
    42601 taaaaaaggt aatacttcac tttatgatca caatgataac acttcagact acagcaaaaa
    42661 tggtgcaggc atagaaaact ataacttcat cactactgct ggtcttaagt acacctttta
    42721 acaacgttaa atagattttc tccccggtgg tattgtatag ccccggggaa tttgtttacc
    42781 gttaaaagca aacaatatcc cctaatcttg taagcattta acctgcgtcc tggcgtgtaa
    42841 cctcttaccg caacacaaga ctcaatatat tcaaattcgt tatgccgtgg catcatttaa
    42901 ccccttgtaa ttcatcgcta taattgattt aattcacaaa taaaactata ac
//
LOCUS       DAPOXO010000039        41054 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.039, whole genome shotgun sequence.
ACCESSION   DAPOXO010000039 DAPOXO010000000
VERSION     DAPOXO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41054
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.039"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            220..1119
                     /gene="lysO"
                     /locus_tag="ROH59_002475"
     CDS             220..1119
                     /gene="lysO"
                     /locus_tag="ROH59_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HDX4804945.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSTTVILLCNIAALMWLERGLPWSNHHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
     gene            1263..2915
                     /gene="hcp"
                     /locus_tag="ROH59_002476"
                     /gene_synonym="priS"
     CDS             1263..2915
                     /gene="hcp"
                     /locus_tag="ROH59_002476"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDX4804946.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIIGYAREAIALREALKAQC
                     LAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            2927..3895
                     /gene="hcr"
                     /locus_tag="ROH59_002477"
     CDS             2927..3895
                     /gene="hcr"
                     /locus_tag="ROH59_002477"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HDX4804947.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSRWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVQVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKTLG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVISGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVFA"
     gene            4028..5746
                     /gene="poxB"
                     /locus_tag="ROH59_002478"
     CDS             4028..5746
                     /gene="poxB"
                     /locus_tag="ROH59_002478"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HDX4804948.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATTHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRVFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKTERKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
                     LPVKIIVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEID
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            5783..6784
                     /gene="ltaE"
                     /locus_tag="ROH59_002479"
     CDS             5783..6784
                     /gene="ltaE"
                     /locus_tag="ROH59_002479"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDX4804949.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQLAEVAAHWRAFLAR"
     gene            6795..8225
                     /locus_tag="ROH59_002480"
     CDS             6795..8225
                     /locus_tag="ROH59_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HDX4804950.1"
                     /translation="MPQRILVLGASGYIGQHLVHTLSQQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLNWPDNLPVLLQNIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQVIFLSSLQAPPHEQSDHLRARQATADILREAGVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPACEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLLPIPLPTRWISVWFLNVITSVPPTTARALIQGLKHDLLADDTAL
                     RALIPQPLIAFDDAVRSTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKT
                     SASLQALWRVVNQIGGKERYFFGNILWQTRALMDLAIGHKLAKGRPEREYLQTGDAVD
                     SWKVIVVEPEKQLTLLFGMKAPGLGRLCFTLEDKGDYRTIDVRAFWHPHGMPGLFYWL
                     LMIPAHLFIFRGMAKRIARLAEQSTD"
     gene            8324..9337
                     /locus_tag="ROH59_002481"
     CDS             8324..9337
                     /locus_tag="ROH59_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDX4804951.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVLTLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(9334..10164)
                     /gene="amiD"
                     /locus_tag="ROH59_002482"
     CDS             complement(9334..10164)
                     /gene="amiD"
                     /locus_tag="ROH59_002482"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiD"
                     /protein_id="HDX4804952.1"
                     /translation="MRRVFWLVAAALLLAGCTGEKGIVEKEGYQLDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVETASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(10161..10484)
                     /locus_tag="ROH59_002483"
     CDS             complement(10161..10484)
                     /locus_tag="ROH59_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDX4804953.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            10610..11125
                     /locus_tag="ROH59_002484"
     CDS             10610..11125
                     /locus_tag="ROH59_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX4804954.1"
                     /translation="MRYSKLTMLIPCALLLSACTTVTPAYKDNGPRTGSCVQGGPDSV
                     AQQFYDYRIQHRSNDITALRPYLSDKLATLLSDASRDNSHRELLSSDPFSSRTTLPDS
                     AHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            11343..12071
                     /gene="artP"
                     /locus_tag="ROH59_002485"
     CDS             11343..12071
                     /gene="artP"
                     /locus_tag="ROH59_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HDX4804955.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            12089..12820
                     /gene="artJ"
                     /locus_tag="ROH59_002486"
     CDS             12089..12820
                     /gene="artJ"
                     /locus_tag="ROH59_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4804956.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDSVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KFNTALEKVKKDGTYETIYNKWFQK"
     gene            12827..13543
                     /gene="artQ"
                     /locus_tag="ROH59_002487"
     CDS             12827..13543
                     /gene="artQ"
                     /locus_tag="ROH59_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HDX4804957.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            13543..14211
                     /gene="artM"
                     /locus_tag="ROH59_002488"
     CDS             13543..14211
                     /gene="artM"
                     /locus_tag="ROH59_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HDX4804958.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            14437..15168
                     /gene="artJ"
                     /locus_tag="ROH59_002489"
     CDS             14437..15168
                     /gene="artJ"
                     /locus_tag="ROH59_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HDX4804959.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGVSATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKINDQWFPQ"
     gene            complement(15197..16324)
                     /gene="rlmC"
                     /locus_tag="ROH59_002490"
     CDS             complement(15197..16324)
                     /gene="rlmC"
                     /locus_tag="ROH59_002490"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HDX4804960.1"
                     /translation="MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVEEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLQE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIAPEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGEVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGYRIERVQLFDMFPHTAHYEVLTLLVKQ"
     gene            complement(16365..16853)
                     /locus_tag="ROH59_002491"
     CDS             complement(16365..16853)
                     /locus_tag="ROH59_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HDX4804961.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            complement(16913..17758)
                     /gene="potI"
                     /locus_tag="ROH59_002492"
     CDS             complement(16913..17758)
                     /gene="potI"
                     /locus_tag="ROH59_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HDX4804962.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVALSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            complement(17755..18699)
                     /gene="potH"
                     /locus_tag="ROH59_002493"
     CDS             complement(17755..18699)
                     /gene="potH"
                     /locus_tag="ROH59_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HDX4804963.1"
                     /translation="MSTLEPAAQPKPFKLWLSQLQMKHGRKLVIALPYIWLILLFLLP
                     FLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQSLQV
                     AAISTICCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKNNGV
                     LNNFLLWLGIIDQPLTILHTNFAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAALDL
                     GARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFF
                     NNRDWPVASAVAIVMLLLLIMPIMWFHKHQQKSEGEHG"
     gene            complement(18709..19842)
                     /gene="potG"
                     /locus_tag="ROH59_002494"
     CDS             complement(18709..19842)
                     /gene="potG"
                     /locus_tag="ROH59_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HDX4804964.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLYSPGLV
                     HPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            complement(19937..21049)
                     /gene="potF"
                     /locus_tag="ROH59_002495"
     CDS             complement(19937..21049)
                     /gene="potF"
                     /locus_tag="ROH59_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HDX4804965.1"
                     /translation="MIALNKKWLSGLVAGALMAVSVSTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKAATPLVSAEVRDNPG
                     IYPPADVRAKLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            complement(21399..21875)
                     /locus_tag="ROH59_002496"
     CDS             complement(21399..21875)
                     /locus_tag="ROH59_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HDX4804966.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            complement(21963..22865)
                     /gene="rimK"
                     /locus_tag="ROH59_002497"
     CDS             complement(21963..22865)
                     /gene="rimK"
                     /locus_tag="ROH59_002497"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HDX4804967.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            complement(22926..23648)
                     /gene="nfsA"
                     /locus_tag="ROH59_002498"
     CDS             complement(22926..23648)
                     /gene="nfsA"
                     /locus_tag="ROH59_002498"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HDX4804968.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALTAAESLGLGGVYIGGLRNNIEAVTELLKLPQHVLPLFGLCLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKDALAQYDEQLAEYYLTRGSNNRRDTWSDHIRR
                     TIIKESRPFILDYLHKQGWATR"
     gene            complement(23632..23919)
                     /locus_tag="ROH59_002499"
     CDS             complement(23632..23919)
                     /locus_tag="ROH59_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1418 family protein"
                     /protein_id="HDX4804969.1"
                     /translation="MRAIGKLPKSVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNHPPQYSRSEREKDNDANH"
     gene            24079..24336
                     /gene="grxA"
                     /locus_tag="ROH59_002500"
     CDS             24079..24336
                     /gene="grxA"
                     /locus_tag="ROH59_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HDX4804970.1"
                     /translation="MQTVIFGRPGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            complement(24366..24743)
                     /locus_tag="ROH59_002501"
     CDS             complement(24366..24743)
                     /locus_tag="ROH59_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HDX4804971.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSHRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            25012..26697
                     /locus_tag="ROH59_002502"
     CDS             25012..26697
                     /locus_tag="ROH59_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HDX4804972.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            complement(26873..27409)
                     /gene="rcdA"
                     /locus_tag="ROH59_002503"
     CDS             complement(26873..27409)
                     /gene="rcdA"
                     /locus_tag="ROH59_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RcdA"
                     /protein_id="HDX4804973.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSRFTEIMSRQYQAFFSDVSDAPGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERIAG"
     gene            27493..28701
                     /locus_tag="ROH59_002504"
     CDS             27493..28701
                     /locus_tag="ROH59_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4804974.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALIGMMVLSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATMHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMMVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            28701..29516
                     /gene="ybjI"
                     /locus_tag="ROH59_002505"
     CDS             28701..29516
                     /gene="ybjI"
                     /locus_tag="ROH59_002505"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415365.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HDX4804975.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFTTVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVPVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGSAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFKQ"
     gene            29602..29886
                     /locus_tag="ROH59_002506"
     CDS             29602..29886
                     /locus_tag="ROH59_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4804976.1"
                     /translation="MIMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(29927..31159)
                     /gene="mdfA"
                     /locus_tag="ROH59_002507"
     CDS             complement(29927..31159)
                     /gene="mdfA"
                     /locus_tag="ROH59_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HDX4804977.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     SLMVIFLKDKQMGNSHEG"
     gene            31444..32040
                     /gene="ybjG"
                     /locus_tag="ROH59_002508"
     CDS             31444..32040
                     /gene="ybjG"
                     /locus_tag="ROH59_002508"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDX4804978.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAAV
                     LWLWGLTAQRQLVIKIAIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRFCFALPIRKGWVRD"
     gene            32098..32856
                     /gene="deoR"
                     /locus_tag="ROH59_002509"
     CDS             32098..32856
                     /gene="deoR"
                     /locus_tag="ROH59_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HDX4804979.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHISKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY"
     gene            complement(32903..34105)
                     /gene="dacC"
                     /locus_tag="ROH59_002510"
     CDS             complement(32903..34105)
                     /gene="dacC"
                     /locus_tag="ROH59_002510"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDX4804980.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRMWDFVMMKFH
                     QWFGSWFS"
     gene            34352..34978
                     /gene="gstB"
                     /locus_tag="ROH59_002511"
     CDS             34352..34978
                     /gene="gstB"
                     /locus_tag="ROH59_002511"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase GstB"
                     /protein_id="HDX4804981.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDTDF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIAPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            complement(34975..36090)
                     /gene="yliI"
                     /locus_tag="ROH59_002512"
     CDS             complement(34975..36090)
                     /gene="yliI"
                     /locus_tag="ROH59_002512"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose sugar dehydrogenase YliI"
                     /protein_id="HDX4804982.1"
                     /translation="MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLP
                     DNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYL
                     FIALGENNQRPTAQDLDKLQGKLVRLTDLGEIPDDNPFIKESGVRAEIWSYGIRNPQG
                     MAMNPWSNALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(36201..36584)
                     /gene="bssR"
                     /locus_tag="ROH59_002513"
     CDS             complement(36201..36584)
                     /gene="bssR"
                     /locus_tag="ROH59_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HDX4804983.1"
                     /translation="MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            36797..38122
                     /gene="rimO"
                     /locus_tag="ROH59_002514"
     CDS             36797..38122
                     /gene="rimO"
                     /locus_tag="ROH59_002514"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDX4804984.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            complement(38169..39497)
                     /locus_tag="ROH59_002515"
     CDS             complement(38169..39497)
                     /locus_tag="ROH59_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDX4804985.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYGLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSVSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKSVTGDEYNAKNAIFTVSEAMEHFSYLPTGLYVF
                     AYKKDVYFQVCTLIIFFAALVAVISGASCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECTTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(39505..>41054)
                     /locus_tag="ROH59_002516"
     CDS             complement(39505..>41054)
                     /locus_tag="ROH59_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDX4804986.1"
                     /translation="FEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRR
                     QFSEMTDLVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERANKLLS
                     LISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGVDERNKIVRKLCQRI
                     AEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIATVNDFDSSFGYRNLRIHKSAICEP
                     LQGENAWSYAEKLKLAISSIRNHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGEL
                     FLVYQPIVDINTRTILGAEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTA
                     MGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSLCVEITET
                     VIERINEHFYLNIEQLRKQGVRVSIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFG
                     TAGKIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDK
                     SGKLVKE"
BASE COUNT        10113 a        10679 c        10177 g        10085 t
ORIGIN      
        1 ccctcgactt atcccttacg gctaccgggt cggcgatttt gacgccacca acaccggtgc
       61 ggtttgtaat taaagcgcaa gaatatcttt aaatgaaaat gaatacccta ccgatcctta
      121 tgcataacat ttccttttaa ttgcaacttt actcgtcctt ccgctttcag tagtgtgtca
      181 tcgcgcattt cgaatcttct ttgcaaggac tgggttttca tgttttctgg gctgttaatc
      241 attctggttc ccctgattgt gggttacctc attccgcttc gccaaaaagc tgcattaaga
      301 gttattaatc agctcttaag ctggatggtt taccttattc tcttttttat gggtatcagt
      361 ctggcgtttc tcgataacct cgccagtaac ttgttggcaa ttctgcatta ttctgccgtc
      421 agtactaccg ttattttact gtgtaatatt gccgccctga tgtggctgga gcgcggcctg
      481 ccatggagca accaccatca gcaagaaaaa ctcccgtcgc gtattgcgat ggcgctggag
      541 tcgctaaaac tgtgcggcgt agtagtgatt ggttttgcca ttggtctgag tggactggct
      601 ttcttacaac acgcgaccga agccagtgaa tacaccttaa ttctgctgct tttcctcgtc
      661 ggtattcagt tgcgcaataa tggcatgacc ttaaagcaga ttgtccttaa tcgccgggga
      721 atgattgtcg ccgtggtggt ggttgccagt tcattaattg gtggtttaat taacgccttt
      781 attcttgatc ttcccatcaa taccgcgctg gcaatggcct ccggtttcgg ctggtattct
      841 ctttccggta ttttattgac cgaatctttt ggtccggtaa tcgggagcgc ggcgtttttt
      901 aatgatctgg cccgtgagct gattgctatt atgttaatcc ctgggctgat tcgccgtagc
      961 cgctctactg cactgggctt atgcggtgcg acgtcgatgg atttcaccct gcccgttctt
     1021 caacgtacag gcgggctgga tatggtcccg gcggcgattg ttcacggttt tattcttagt
     1081 ctgttagtgc cgattctcat cgcctttttc tctgcataat acctctctgg cggtagatct
     1141 ctgccgccaa aattgcgcta aatcaatctc ccttaaagtt gcattaaaaa tctcttttat
     1201 ccccgcgtta agcgtcttaa ccttaaacat gtatattaaa tataacttta aaaggtgtga
     1261 tcatgttttg tgtgcaatgt gaacaaacta tccgtactcc ggcaggaaac ggctgctcat
     1321 acgcgcaggg gatgtgtggt aaaacggcgg aaacctctga ccttcaggat ttactcatcg
     1381 cgacgctgca agggctttcg gcctgggcag tgaaagcacg tgaatacggc atcatcaacc
     1441 acgatgtaga cagctttgcg ccacgtgcct ttttctcaac cctgaccaac gttaacttcg
     1501 attctccgcg tattatcggc tacgctcgtg aagcgattgc cctgcgcgag gcgctgaaag
     1561 cacaatgcct ggctgtagat gccaacgccc gcgtcgataa cccgatggct gacctgcaac
     1621 tggtgagcga cgatctcggc gagctgcaac gtcaggcagc agaatttacc cctaacaaag
     1681 ataaagcggc gattggcgaa aacattctcg gcctgcgtct gctgtgcctg tatggcctga
     1741 aaggtgcggc ggcctatatg gaacacgcgc atgttctcgg tcaatacgac aacgatattt
     1801 atgcccagta ccataaaatc atggcgtggc tggggacctg gcctgccgat atgaacgcgc
     1861 ttcttgagtg ttcaatggaa atcggccaga tgaacttcaa agtgatgagc attctggacg
     1921 caggcgaaac cggtaaatac ggtcacccga ccccaaccca ggtcaatgtc aaagcgacgg
     1981 caggtaaatg catcctgatt tccggtcacg atctcaaaga tctctacaac ctgctggaac
     2041 agaccgaagg cacgggcgtt aatgtctaca cccacggcga aatgctgcct gcgcatggtt
     2101 acccggagct gcgtaaattc aagcatctgg tcggtaacta cggcagcggc tggcagaatc
     2161 agcaagtgga gttcgctcgt ttcccaggcc ccatcgtgat gacctcgaac tgcatcatcg
     2221 acccaaccgt aggcgcttat gacgatcgta tctggacccg cagcatcgtt ggctggccgg
     2281 gtgtgcgcca tctggatggc gaagatttct ctgcggtcat tgcccaggcg caacagatgg
     2341 cgggcttccc gtacagcgaa attccgcacc tgatcaccgt gggctttggt cgccagacac
     2401 tgcttggcgc agccgatacg ctgattgatc tggtgagccg tgaaaaactg cgtcatatct
     2461 tcctgcttgg cggctgtgac ggcgcacgcg gcgagcgtca ctacttcacc gatttcgcca
     2521 ccagcgtgcc ggatgactgc ctgatcctga ccctcgcttg cggtaaatat cgctttaata
     2581 aacttgagtt tggcgatatc gaaggtctgc cgcgtctggt agatgctggt cagtgtaacg
     2641 atgcttactc agcaattatt ctggcggtaa cgctggcaga gaaactgggc tgcggagtca
     2701 acgatctgcc gctgtcgctg gtgctctcct ggtttgaaca gaaagcgatt gtcattctgc
     2761 tgacgctgct ttctctgggt gtgaaaaata tcgtcaccgg cccgactgca cctggtttcc
     2821 tgacaccaga cctgctggcg gtgctgaacg agaaattcgg cctgcgttct atcaccactg
     2881 ttgaagaaga catgaagcaa ctgttgagcg cgtaaggagt ttgtcgatga cgatgccaac
     2941 gaatcaatgc ccgtggcgga tgcaggttca tcacattacg caagaaacgc cggatgtgtg
     3001 gacgatttcc ctgatttgcc acgattacta cccgtatcgc gccgggcaat atgcgctggt
     3061 cagcgtgcga aactcagcag aaacgctgcg tgcttacacc atttcctcca cgccaggcgt
     3121 gagtgaatac atcaccctga ctgtgcggcg gattgatgac ggtgtcggct cccggtggct
     3181 gacgcgcgat gtaaaacgcg gtgattatct ctggctttcg gacgcgatgg gggaatttac
     3241 ctgcgacgat aaagcagaag ataaattcct gttgctggcg gcaggctgcg gcgtcacgcc
     3301 gattatgtcg atgcgtcgct ggctggcgaa gaaccgtcca caggccgatg tgcaggtgat
     3361 ctacaacgtg cgtacgccgc aggatgtgat tttcgccgat gagtggcgta actatccggt
     3421 aacgctggtg gcggaaaata acgttaccga aggctttatc gctggtcgtc tcactcgcga
     3481 actgctggca ggtgtccctg atttagcctc acgtaccgtg atgacctgtg gccctgctcc
     3541 atatatggat tgggtagagc aggaagtgaa aacgctcggc gtgacgcgtt tctttaaaga
     3601 gaaattcttc accccagtag cggaagcggc gaccagcggt ctgaaattca ccaaactgca
     3661 accggcacga gaattttacg ctccggttgg caccacgcta ctggaggcgc tggaaagcaa
     3721 taacgttccg gttgtcgccg cctgccgtgc gggtgtttgc ggctgctgta agacgaaagt
     3781 gatttccggt gaatatacgg tgagcagcac aatgacgctg accgacgccg aaatcgctga
     3841 aggttacgta ctggcctgct catgccatcc gcagggggat ttggttttcg cataatcgcc
     3901 tgatgcccga tgatattcct ttcatcgggc tatttaaccg ttagtgcctc ctttttctcc
     3961 catcccttcc ccctccgtca gatgaactaa acttgttacc gttatcacat tcaggagatg
     4021 gagaaccatg aaacaaacgg ttgcagctta tatcgccaaa acactcgaat cggcaggcgt
     4081 gaaacgcatc tggggagtca cgggcgactc tctgaacggt cttagtgaca gtcttaatcg
     4141 catgggcacc atcgagtgga tgtccacccg gcatgaagaa gtggcggcat ttgccgctgg
     4201 cgctgaagca caacttagcg gagaactggc ggtctgtgcc ggatcgtgcg gtcccggcaa
     4261 cctgcactta atcaacggcc tgttcgattg ccaccgcaat cacgttccgg tactggcgat
     4321 tgccgctcat attccctcca gcgaaattgg cagcggctat ttccaggaaa cccacccaca
     4381 agagctattc cgcgaatgta gtcactattg cgagctggtt tccagcccag agcagatccc
     4441 acaagtgctg gcaattgcta tgcgcaaagc ggtgcttaac cgtggcgttt ccgttgttgt
     4501 gttaccgggc gatgtggcgt taaaacctgc gccagaaggg gcaactaccc actggtatca
     4561 tgcgccacag ccggtagtaa caccggaaga agaagagtta cgcaaactgg cgcaactgct
     4621 gcgttattcc agcaatatcg ccctgatgtg tggcagcggc tgtgcggggg cgcataaaga
     4681 gttagttgag tttgccggga aaattaaagc gcctatagtc catgccctgc gcggtaaaga
     4741 acatgtcgaa tacgataatc catatgatgt tggaatgacg ggattaatcg gcttttcgtc
     4801 aggtttccat accatgatga acgccgatac gttagtgctg ctcggtactc agtttcccta
     4861 ccgtgtgttc tacccgaccg atgccaaaat tattcagatt gatatcaacc cagccagcat
     4921 cggcgcgcat agcaaggtag atatggcgct ggtcggcgat atcaaatcaa ccctgcgcgc
     4981 attgctgcca ctggtggaag aaaaaaccga acgcaagttt ctggataagg cgctggaaga
     5041 ttaccgcgac gcccgcaaag ggctggacga tttagctaaa ccgagcgaga aagccattca
     5101 cccgcaatat ctggcgcagc aaattagtca ttttgccgcc gatgacgcta ttttcacctg
     5161 tgacgttggt acgccaacgg tgtgggcggc acgttatcta aaaatgaacg gcaagcgtcg
     5221 cctgttaggt tcgtttaacc atggttcgat ggctaacgcc atgccgcagg cgctgggcgc
     5281 gcaggcaacc gagccagaac gccaggtggt cgccatgtgc ggcgatggcg gttttagcat
     5341 gttgatgggc gatttcctct cggtagtgca aatgaagctg ccagtgaaaa ttatcgtctt
     5401 taataacagc gtgctgggct ttgtggcgat ggagatgaaa gctggtggct atttgactga
     5461 cggcaccgaa ctacacgaca ccaactttgc ccgaattgcc gaagcctgcg gcattacggg
     5521 tatccgcgta gaaaaagcgt ctgaaatcga tgaagccctg caacgcgcct tctccatcga
     5581 cggtccggtg ttggtggatg tggtggtcgc caaagaagaa ttagccattc caccgcagat
     5641 caaactcgaa caggccaaag gtttcagcct gtatatgctg cgcgcaatca tcagcgggcg
     5701 cggtgatgaa gtgatcgaac tggcgaaaac gaactggcta aggtaaaaag ggtggcattt
     5761 cccgtcataa taaggacatg ccatgattga tttacgcagt gataccgtta cccgaccgag
     5821 ccgcgccatg ctcgaagcga tgatggccgc cccggttggg gacgacgttt atggagacga
     5881 ccctaccgtt aatgctctgc aggactatgc agcagagctt tccggtaaag aagccgccat
     5941 ttttctgcct accggcactc aggccaacct ggtcgctctg ctcagtcact gcgaacgcgg
     6001 cgaagagtat atcgtcggtc aggccgcgca taactatctg tttgaagccg gtggcgcagc
     6061 agtactgggc agtattcagc cgcaacccat cgacgcagct gccgacggta cgctaccgct
     6121 ggataaagtg gcgatgaaaa tcaaacccga cgatatccat ttcgcccgca ccaaattact
     6181 cagtctggaa aacacccaca acggcaaagt gctgccgcgt gaatacctga aagaagcatg
     6241 ggaatttacc cgcgagcgca atctggcgct gcacgttgac ggtgcgcgca tttttaatgc
     6301 cgtggtggct tacggctgcg aactgaaaga gatcacgcaa tattgtgact cgttcaccat
     6361 ttgcctgtcg aaaggtcttg ggacgccagt cggttcatta ctcgtcggta atcgtgatta
     6421 cattaaacgt gccattcgct ggcggaaaat gacaggtggc gggatgcgtc agtccggcat
     6481 tctggctgcc gccgggatgt atgcgctgaa aaataacgtc gcacgtttgc aggaagacca
     6541 cgataacgcc gcctggatgg cggagcagtt gcgtgaagca ggcgcggatg tgatgcgtca
     6601 ggacaccaat atgctgtttg ttcgcgtcgg ggaagaaaat gctgccgcgt taggcgaata
     6661 catgaaagcg agaaacgtgc tgattaacgc ctcgccgatt gtccgcctgg tgacccatct
     6721 tgacgtctcg cgtgaacaac tggcggaagt tgccgcccac tggcgtgcgt tcctggcgcg
     6781 ttaaggagag agacgtgccg caacgcattt tagttctcgg tgccagtggc tacattggtc
     6841 aacatctggt gcacacactc agccagcaag ggcatcagat cctggcggcg gcacgtcacg
     6901 tcgacagact tgcaaaactg caactggcta atgtcagttg ccataaagtc gatctcaact
     6961 ggccggataa ccttccggtc ctgttgcaga atattgatac tgtctatttt ctggtgcaca
     7021 gcatgggcga aggtggtgat tttatcgctc aggagcgcca ggtggctctc aacgtccgcg
     7081 atgcgctgcg cgaagtaccg gtaaagcaag tcatctttct cagttcattg caggcaccgc
     7141 ctcatgaaca atctgatcat ctgcgtgctc gtcaggccac ggcggatatt ttacgtgaag
     7201 cgggtgtccc ggtgaccgaa ctacgtgccg gaattatcgt tggcgcgggt tcagcggcat
     7261 tcgaagtcat gcgcgatatg gtttacaacc tgccagtatt aacgccacca cgctgggtac
     7321 gttcacgcac tacgcccatc gcgctggaaa acctgctgca ctatcttgtg gcgctgttag
     7381 atcatccggc ttgcgaacat cgcatcttcg aagccgctgg gccagaagtg ctcagttatc
     7441 agcaacagtt tgaacatttt atggcggtga gcggtaagcg ccgctggttg ctccccatcc
     7501 ccctccccac ccgctggatt tcggtgtggt ttcttaatgt gattacttca gtaccgccca
     7561 ccaccgccag agcgttgatt caggggctga aacacgatct gctggcggat gacaccgcgt
     7621 tacgtgcact cattccacaa ccgctgatcg ctttcgatga cgcggtacgt agcacgttga
     7681 aagaggaaga aaaactggtc aactccagcg actggggata tgacgcgcag gcttttgctc
     7741 gctggcgacc agaatacggt tattttgcca aacaggcggg gtttaccgtt aaaacgtctg
     7801 ccagccttca ggcgctatgg cgggtggtca atcaaatcgg cggtaaagag cgttatttct
     7861 ttggcaatat tttgtggcag acacgggcgt tgatggacct tgcgatcggt cataagctgg
     7921 caaaaggccg cccggagcgc gaatatttac agaccggcga tgctgtggat agctggaaag
     7981 tcattgtcgt tgaaccggaa aaacaactta cgttgttatt tggcatgaaa gcgccggggc
     8041 tgggacgact ctgttttacc ctggaagata aaggcgacta tcgtacaatc gatgtccgtg
     8101 ctttctggca tccgcacggt atgccggggc tgttttactg gttattgatg atccccgcgc
     8161 atctgtttat ttttcgcgga atggcaaaac gaatcgccag actggcagaa caaagcacag
     8221 attaatcgac aaaacctgcg ttattctttc atgtttccca ttgcatcaag ggggaaatca
     8281 cggaagaatg cgcacgtcat tttctcaaca acagtggatt gatatgaagg tactggttac
     8341 cggcgccacc agcggcttag gtcgaaacgc ggtagagttt ttatgccaga aaggcatcag
     8401 cgtgcgagcg accggtcgca acgaggcaat gggtaaattg ctggaaaaaa tgggcgcaga
     8461 gtttgttccg gcggatctga ccgagttggt ctcatcacaa gctaaagtga tgctcgcggg
     8521 cattgatacg ctgtggcact gctccagctt tacctcgccc tgggggacac aacaggcttt
     8581 cgatctggct aacgttcgcg ccactcgccg cctgggtgaa tgggctgtcg cctggggtgt
     8641 gcgtaacttt attcatatct cttctccctc cctgtacttc gattatcacc accatcgcga
     8701 tattaaagaa gattttcgcc ctcaccgctt cgccaacgag tttgcccgca gcaaagcagc
     8761 cagcgaagaa gtgatcaata tgctttcgca ggcgaatcca caaacgcgct ttactattct
     8821 gcgcccacaa agtctgttcg gaccgcacga taaagtcttt atccctcgtc tggcgcatat
     8881 gatgcatcac tacggcagta ttctgttacc gcatggcggc agtgcgctgg tcgatatgac
     8941 ctactatgaa aatgccgtgc acgccatgtg gctggcaagc caggaagcgt gcgataagct
     9001 accttccggg cgtgtgtaca acatcaccaa cggcgagcat cgcacactgc gcagcatcgt
     9061 gcagaagctg atcgacgagt tgaatattga ctgtcgtatt cgttcggttc cttacccgat
     9121 gctggatatg atcgcccgca gcatggagcg tttaggccgc aagtcagcaa aagagccgcc
     9181 gctgacccac tacggcgtct ccaagttgaa ttttgacttt acgctggata ttacgcgtgc
     9241 gcaggaagag ttaggttatc agccagtcct caccctggat gaaggtatcg agaaaactgc
     9301 cgcctggctg cgcgaccacg gaaaactgcc gcgctaatcc tgcccgtatt tctccagcaa
     9361 cgcttcggca atcgcctgag tttctgcatc cgcttcgccg ttatataacg tcgggcggaa
     9421 atgcatctgg aacgccataa tcacacgccg ctgctcgcgc ggagtcatat caggctttac
     9481 gtcataacca taacgcgcca aaagctccag caatgacgcg gtctctaccg gtgtgtgcgg
     9541 cgcgcgcccg gcaaggtaaa agttcacccg ctgcgcatcc ggccaggcac caatcccctg
     9601 ctgtgccagt tgctgccagg gaaataatgg ccccggatcg tctttgcgct gtggcgcaat
     9661 atccgcatgt gctactacgt tttccggctt gatgtgataa cgggcaataa tatctttcgc
     9721 cagcggaata agcgcctgaa tctgtgccgg ttcaaacggg gcaaaatatt tcactcccgc
     9781 cgatttttgc cagccacggt tttccagctc aatgccaata gaggtgtcgt taagacgcgt
     9841 tgccccgcgc caggcgctaa tccccgcatg ccaggccagt tcttgttccg gcaccagttg
     9901 ccagatgcgc ggtttaccgt tgtatcgcgg tggcaccgca gggaccagat aatgcgagct
     9961 gacctgctta tcggtcagtg tcgccagcga gctatcaaaa tcatctgcgg tgtagtggat
    10021 caccagcact ttaatgcgcg gatacgccgc ctgcgcctgg cgtcgggtat caagctgata
    10081 tccctctttc tcgacaatgc ctttttcgcc tgtgcaccct gccagtaaca gagcggcagc
    10141 gaccagccag aagactcttc tcatcgacgc gttttcaccg ccgtaccgct gacgctaacc
    10201 atcagcatac tgccgttttg cccgaccgtt tcgtagtcga tatcaatacc gacgacggca
    10261 tcagccccca gcgctcgcgc ctgggagccg agctcctcaa aggcaatctc ccgcgcttta
    10321 cgcagttctt tttcgtaggc accggagcgt ccgccaacga tatcgcggat accggcaaag
    10381 aaatcacgga aaatattcgc gcctaaaatc gcttcgccag tcaccacacc gcaatattca
    10441 acgatggtct ggccttccag agttggggtt gtagaaaatt gcatgatcga tctccttgtt
    10501 tgctaagcct tcgatcttca aagcattatc ggactgatac gctattattg aaaggatatc
    10561 attattatcg tagaacgctt tcaaggtgtt cgcttataag gaaatcatca tgcgctatag
    10621 caaattgacc atgcttatcc cttgcgcact gctactcagt gcctgtacca ccgtcacgcc
    10681 agcttataaa gataacggcc cccgcaccgg ttcctgtgtc cagggggggc ctgatagtgt
    10741 ggctcaacag ttctatgact accgcattca acatcgcagc aatgacatta ccgctctgcg
    10801 cccctatttg agtgacaaac tggcaaccct acttagcgat gccagccgcg ataatagtca
    10861 tcgtgaattg ttaagcagcg atccgttctc cagtcgaacc accttgccag acagcgccca
    10921 cgtagccagt gcatcgacta tccctaatcg tgatgcccgt aacattccat tgcgcgtgga
    10981 tctcaagcag ggtgaccagg gctggcagga tgaagtgtta atgattcagg aaggccagtg
    11041 ttgggtcatc gacgatgtgc gctacttagg cggtagcgtt catgccacgg cgggtacgct
    11101 ccgtcaatcc atcgagaatc gctaacgtct tgatcaacca ataaaccccg taaattgtcc
    11161 ggcatttcgt gaggaatgcc gacatttatg ctcgccgacc accgcccccg ttattttgtg
    11221 ctatgtttat tgaataatgc gctttgcttt taacttttaa agcagaaata ttgcataatt
    11281 attctgtcaa aggtactatc ttcgacctca atagctatca gactgccagt atacgagtgt
    11341 caatgagtat tcaattaaac ggcattaatt gcttctacgg cgcgcatcag gcgctgttcg
    11401 atatcacgct ggattgcccg cagggcgaaa cgctggtgtt acttggcccc agcggcgcgg
    11461 gtaaaagctc gctgctgcgt gtactcaatc tgcttgagat gccgcgctcc ggtacgctca
    11521 acattgcagg caaccatttc gatttcacca aaaccccctc tgacaaagcg attcgcgatt
    11581 tgcgtcgtaa cgttggcatg gtgtttcagc aatacaacct gtggccgcat ctgaccgtgc
    11641 agcaaaacct gattgaagcg ccctgccgtg tactggggct gagtaaagat caggcgctgg
    11701 cccgtgcaga aaaactgctg gaacgtctgc gtcttaaacc ttatagcgat cgttacccgc
    11761 tgcatctttc tggtggtcag cagcagcgtg ttgctattgc ccgtgcgttg atgatggaac
    11821 cgcaggtact gctgttcgat gaaccgaccg ccgcactgga ccccgaaatt acggcacaaa
    11881 tcgtcagcat cattcgtgag ctggcagaaa cgaatattac ccaggtgatc gtcacccacg
    11941 aagttgaagt ggcgcgtaaa accgccagcc gagtggtgta tatggaaaac ggtcatatcg
    12001 tagaacaagg cgacgcgagc tgctttaccg agccgcaaac cgaagcattt aaaaactatc
    12061 tctctcacta agattcggga taacaacaat gaaaaaagtt ctgattgccg cgttaattgc
    12121 aggttttagt ctttccgcca cagcagccga aaccattcgt tttgccaccg aagcctccta
    12181 tcctccgttt gaatcgattg atgcaaacaa ccagatcgtt ggttttgatg tcgacctggc
    12241 gcaggcattg tgtaaagaga ttgatgcaac ctgcactttc tctaaccagg cgtttgacag
    12301 cctgatccca agcctgaaat tccgtcgcgt agaagcagtg atggcgggca tggatatcac
    12361 tccggagcgt gaaaagcagg tgctgtttac caccccgtac tatgacaact ctgccctgtt
    12421 tgtgggtcag caaggcaaat acaccagtgt tgatcagctg aaaggcaaaa aagttggcgt
    12481 tcagaacggg acgacacacc agaagttcat tatggataag catccggaaa tcactaccgt
    12541 gccatatgac agttaccaga acgcaaaact ggatctgcaa aacggtcgta tcgacagcgt
    12601 atttggtgac accgcagtgg taactgaatg gctgaaagat aacccgaaac tggcggcagt
    12661 gggcgataaa gtgaccgata aagattactt cggtactggc ctcggcatcg cagtacgcca
    12721 gggcaacact gaactgcagc agaaattcaa cactgcgctg gaaaaagtga agaaagatgg
    12781 cacttacgaa accatctaca acaaatggtt ccagaagtaa ttcctgatga atgaattttt
    12841 tcctttagca agcgccgccg ggatgaccgt cggccttgcc gtttgtgcat tgattgtcgg
    12901 gctggcgctg gcgatgttct ttgcggtatg ggagtctgcg aaatggcgtc ctgtcgcgtg
    12961 ggcaggttca gcgctggtaa ccattctgcg tggcctgcca gaaattctgg tggtgctgtt
    13021 tatctatttt ggctcctcgc agctgctgct gacgctttcg gatggcttca ctatcaatct
    13081 tgggttcgtg cagatcccgg tgcagatgga cattgagaac ttcgacgtta gcccgttcct
    13141 ttgtggtgtc atcgctctgt cactgctgta tgccgcctat gcctcgcaaa cgctgcgtgg
    13201 tgcattaaaa gcggtgccgg tggggcagtg ggaatccggt caggcgctgg ggctgtcgaa
    13261 atcggctatc tttttccgtc tggtgatgcc gcagatgtgg cgtcatgcgc tgccgggtct
    13321 cggtaaccag tggctggtgc tgctgaaaga taccgcgctg gtcagtttga ttagtgtgaa
    13381 tgatttaatg ctacaaacca aaagcatcgc tacccgtacc caggaaccgt ttacctggta
    13441 cattgtggcg gcggcgattt acctggtgat caccctgctc agtcagtaca ttctcaaacg
    13501 cattgacctg cgcgcgacac gttttgagcg gaggcccagc taatgtttga gtatttaccc
    13561 gaactgatga aagggctgca caccagcctg acgctaaccg ttgcctcgct gattgtggca
    13621 ctgattctgg cattgatttt taccatcatc ctgacgctga aaacgccggt gctggtgtgg
    13681 ctggtacggg gctatatcac gctgtttacc ggtacgccgc tgctggtgca gatcttcctg
    13741 atttattacg ggccgggcca gttcccgacg ttgcaggagt atccggcact gtggcatttg
    13801 ttgtcagaac cgtggttatg tgcgctgatt gcgttgtcgc tgaacagtgc ggcgtacacc
    13861 acgcagctgt tttacggtgc gattcgcgcg atcccggaag gtcaatggca gtcctgtagc
    13921 gccctgggaa tgagcaaaaa agatacgctg gcgatcctgc tgccgtacgc gtttaaacgc
    13981 tcgctctctt cttattccaa cgaagtggtg ctggtgttca aaagtacctc tctggcttac
    14041 accattacgc tcatggaagt gatgggatac agccagttgt tgtacggacg cacctacgat
    14101 gtaatggtat ttggcgcggc ggggattatt tacctggtcg tcaacggcct gctgacgctg
    14161 atgatgcgtc tgatcgagcg taaagcactg gcattcgaac ggcggaatta atgtagctgc
    14221 atgctgatgc cggatgcggc gtggacgcct tatccggcct acatagtgca taaattctta
    14281 ttatgaagac ggacaaccca ctaagctgtc cgtctttttt tatttcatat aaattattta
    14341 ctcatattta ttgcatataa attcacttaa tggcattgtt atcccatgcc gcagacacgg
    14401 ccaaaaatca taagattgac agacgggagt tccatcatga aaaagttagt tcttgccgct
    14461 ttacttgctt cttttacttt cggtgcttct gccgcagaga aaatcaattt tggcgtttca
    14521 gccacctatc caccctttga atctataggt gctaataatg agattgtcgg ctttgatatc
    14581 gacctggcaa aagccttgtg caaacaaatg caggcagaat gtacttttac taatcacgct
    14641 ttcgacagcc tgatcccgtc actgaaattc agaaaatatg acgccgtaat ctccggaatg
    14701 gatatcacgc cggagcgtag caaacaggta tcgtttacca cgccctacta cgaaaactca
    14761 gccgtcgtga ttgccaaaaa agatacctac aaaacgtttg ccgatctgaa aggcaaacgt
    14821 attgggatgg aaaacggcac cacgcaccag aaatatattc aggatcagca cccggaagtg
    14881 aaaactgtct cctatgacag ttatcagaat gcctttatcg atctgaaaaa tggccgtatt
    14941 gatggcgtat ttggtgacac cgcagtggta aacgaatggc tgaaaaccaa tccgcaactg
    15001 ggcgttgcta ctgaaaaagt gaccgatccg caatacttcg gcaccggcct gggtatcgct
    15061 gtacgtccgg ataacaaagc tctgctggaa aaactgaata acgcgctggc agcaattaaa
    15121 gctgacggta catatcagaa aatcaatgac cagtggttcc cacagtaaga ttcagaaagc
    15181 cgcacctgcg gcttttttat tgcttcacca gtagcgtcag cacttcatag tgcgcggtgt
    15241 gcgggaacat atcaaaaagc tgtacccgtt cgatgcgata accaggcagt tcgcggatat
    15301 ctttcgccat agtttgggcg ttacagctgg agtagataat aaaacgcggt gccatcgttg
    15361 agagataatc acacagcggt ttaccgatgc cgcggcgcgg cgggttaacc agcaccagct
    15421 ccggcacttc cccctgagcg gtggcaaact gcgtagagtc cagcgcctga aattgcaaac
    15481 gcgttaagcc cagttcagcg gctgactgct tcgcacaggc aatggcctct ggtgcaattt
    15541 cgatcccggt taactgcatg tcaggcgtcg cgcagtgtaa accaaagcca cccacaccgc
    15601 agaacagatc ccacatatgt ttaaccggca gctgtcgtac ccagtcgcgc gcggtggcgt
    15661 acagctggct ggcgaccgcc ggattagtct ggaagaaact ttgcggacgg atccacagcg
    15721 gtacgtcatt aaaacgctct gccagtgcct gttgttcggt caggtagatc tccgtctccc
    15781 cttccataat cgccatatgt accggctgaa tattgacggt aataactttc agctgcggta
    15841 attgttcctg taaccacggc agcgccttac gcaattgcgc cagtttggta tcagaacgca
    15901 gtacaaaacg cagcatcatg ccaccatcgc tctggctttc agtcagcaga atgtatttca
    15961 gttcaccacg tttacgcgcc acgttgtagg gcgttaaccc cgcacgggcg ataaacggtt
    16021 ttagcgccgc aaaaacgggc gcaaatgagg ctggataaag cgggcagtca caaaggtctt
    16081 ccggtgtacc atctcgatgc agcataccga gcagtggttt ttcaacgcta ccactcacca
    16141 ccattttggc tttattacga aacccttgtt ccgggcctga caccggcgca caccattcct
    16201 caaccggaaa atcggcgagc agatttttaa gatcggcagt tttagcggag agttgctctg
    16261 gaatcggctg cgttatccac tgacaggaac gacagcgacc cgcgtcgtaa agtgcgcact
    16321 gcatacattg accttcacat catcaggggc gacgattata cacattattg caactggaag
    16381 aaccgccgac tggtcgaggg aacgaacagc agcatcagga tgagcatatc cggcagcttc
    16441 tgcagcatca ggctatggaa gatttcacgt tttgattcac cgggaatgct gaacagctcc
    16501 ggataaccat accccagcga agccgcccac aagtaacttg cggctgtgat ttgtgtcaac
    16561 agatacagcc agcgcgccca gcgacgccct ttcaccagtg aaaacgcaca ccagatctca
    16621 atgaaaacca gcaccagact gctcaaaaag accagcgtta aactccaggt ttgtacgctg
    16681 cgatgaatga actcgccaat accgcgcacg cccagcgtat tgaaaatcat cagcacgtcg
    16741 aggccacgga tcataataat ggcgagcgcc gccacctgca ccagcgcagg cacattcagg
    16801 cgagcatgag atgaagatgt tttcttaaaa aatcccaacg tttcgtcttc catgaaaaca
    16861 atgccgcgac atgcgcggca ttatgtagcc aggttggcaa attttagtgt cttcagccac
    16921 gtcttgcacg ctggatgtcg cgtatccgct gtttttctgc gcgcgccatc agataccagg
    16981 cgataaatcc gacaattccg accgcgccga ggatcaatgt tgccagggcg ttgatttccg
    17041 gattcacccc catccgcacg ctggaaaaga ccagcatcgg taatgtggtg gctcccggcc
    17101 cggaaacaaa gctggcgatc accagatcat caagcgacaa agtaaaagcc agtaaccagc
    17161 cagaaatgat cgcgggcatg atcatcggta gcgtaatgac aaaaaacact ttcagcggcg
    17221 tcgcaccgag atccatcgcg gcttcttcta tcgagcgatc cagttcccgc agacgcgacg
    17281 aaataacgac tgccacataa gccgtacaga aagtgacatg cgccagccag atggtgagca
    17341 taccgcggtc cgcaggccag ccaatagcat gagcaagcgc gacgaataac aacaacagcg
    17401 acaaacccgt gatgacatct ggcattacca gcggtgcggt gatcatgaag gcaaaaccat
    17461 ttgatccgcg aaacctgcca aagcgcacca gcacgaccgc cgcaatagtc ccgaggatcg
    17521 ccgccgccgt cgccgcacag gccgcaattg tcagacttaa agcaaccgca ctcatcatcg
    17581 cgtcatcgcg caataattcg ccataccagc gcgttgacca gccggcccac accgtcacta
    17641 gcttcgagct gttaaacgaa tagataacaa gcatcagcat tggcgcgtag agaaaggtga
    17701 agcccaacag caaaatcaca atccgccagg gcgaacgaac caccggtaaa ttattcatcc
    17761 gtgttctccc tcgctttttt gctgatgttt gtggaaccac attatcggca taattagcag
    17821 cagcaacatg acgatcgcta ccgctgaggc caccggccag tcgcggttgt taaagaactc
    17881 ctgccacagc acgcgcccga tcatgatgct gtccgggcca ccgagcagtt ccgggatcac
    17941 aaactcgccc acagccggga taaacaccag catcgatccg gcaataatcc cacctttagt
    18001 cagcggcacg atcacagtaa agaacgtttt cagcggtcgt gcaccgagat ccagtgccgc
    18061 ttctaccagc gaataatcaa tacgaatcaa cgcggtgtaa atcggcagca ccataaacgg
    18121 cacgtaggcg taaacaatgc caatataaac cgcaaagttg gtatgcagaa tggtcagcgg
    18181 ttgatcgata atccccagcc acagcagaaa attattcagc acaccgttgt tttttaatat
    18241 tcccatccag gcgtagacac gaatcagaaa cgaggtccac gacggcagga tcaccagtag
    18301 taataagata ttacgggtcg aaggcttact gtgcgccacc gcccacgcca gcggatagcc
    18361 gatcagtaaa cagcaaatag tcgaaatcgc cgccacctgt aacgactgga gataagcatc
    18421 aaaatagagc ggatcgtcgg tcagttgcag aaaattaccg agattaagag tgatagaaag
    18481 ttgcccgtca gcccactcca tcaattcggt ataaggtgga atagcgcgcg ccatctccgc
    18541 caggcttatt ttaaagacga tcagaaatgg cagcagaaac agcaagatca accagatata
    18601 cggcaacgca ataaccagtt tgcgcccatg tttcatttgc agctgcgaca accacagctt
    18661 aaagggtttt ggctgggcag caggttcaag tgtactcatc tttgctcctt aaaccgtcag
    18721 caccacacag ctgtccactt cccagcacaa acgcacttcg tcgccccagg tcggtaaccc
    18781 tttacgatga cgatgggcgt tttgtagctg ggcgctaatc atctgcccac ttttcagacg
    18841 aacgtgatac accgaaagat cgccgagata ggcaatgtgt atcacctccc ccaccgcgaa
    18901 gttacaacca ttggcgggcg gttcctcgca aagcatgatt ttttccgggc gaagcgccac
    18961 atgcaccggc acgttatcga ccactgaagc atccgcatcg actttcagtg gatgcaccag
    19021 ccccggcgaa taaagcacca gaccatcttc ctgacgctct ttgagtacac cttcaaagac
    19081 attaaccgaa ccgataaatt cagcactgta gcgagtggtc ggatgctcgt agatctcttc
    19141 cggctcgcca atctggacaa atttcccacg attcataatg gcgatgcgcc ccgccatagt
    19201 catcgcctct tcctgatcgt gagtaaccat tacgcaggtc acaccgacgc gctccagaat
    19261 atccaccact tcaagctgca tccggtcacg cagcttttta tccagcgcgc ccatcggctc
    19321 atcgagcagt aatagtttcg ggcgcttggc aaggcttctg gccagggcca cacgctgacg
    19381 ctgaccacca gaaagctgat gcggtttgcg tttggcgaac tcctgcatat gcaccagccc
    19441 aagcatctca ttgacccggc tggcaatttc cgctttcggt agtttgtcct gtttcaggcc
    19501 aaaagcgatg ttctgttcca cggtcatatg cggaaacagc gcgtaagact gaaacatcat
    19561 attgatgggg cgcaggtaag gcggcacctg tgacaaatcg acgccatcga gcataatctg
    19621 cccggccgaa ggttgttcaa aacctgccag catacgcagc agcgtggact tgccacagcc
    19681 ggatgcgccc agcagcgcga agatttcacc tttgtagatg gtcaggctga catcatccac
    19741 cgcatgttga ccatcgtagg atttggtcag gttacggatt tctaatagcg gcgtcagcgc
    19801 cttacgggtt ttcgcctgcg ggcgagggat agcgtcattc acggctgctc tccggcattg
    19861 aatgtgtgca agcgcaccat gatggtgcga attgccggcg ggtgtggtgc gcccctccgg
    19921 catctacggc tgcggattat tttccgctct tcactttggt ccaggcgcgg gtgcgcacac
    19981 ggtcgatttt cgggtcctgc actttcagag tgaacagctt cgcacgaaca tccgcaggcg
    20041 gataaatacc cgggttatca cggacttccg cactcaccag cggcgtggct gctttattgg
    20101 cgttagcata gaacacatgg tcagagatat gtgccaccac atcaggacgc agcaggtaat
    20161 tcaggaactg ataggcttcg tctttgtttt tggcatccgc aggcatggcg aatacatcaa
    20221 agaacgccat cgccccttct tttggaatcg agaacgagac attcacgcca ttcttcgctt
    20281 ccttcgcgcg gtttgacgcc tgccagacat cgcccgccca gccaatagcg acacagatgt
    20341 caccattcgc cagatcattg atgtattggg atgaatggaa ataacgaatg ttcgggcgca
    20401 gctttaacag cagatcggta gccggtccgg tgtaatcatc cgctttagtg ctgttaggat
    20461 ctttgccgag ataattcagc acggtagcaa acacttcttc tggcgcatcc aggaaagaga
    20521 caccgcagct tttcagtttt tccagatttt caggtttgag gatcaagtcc cagctatcga
    20581 cgggcgcgtt ttcgcccagc accgctttaa ctttatcgac gttatagcca atcccggtcg
    20641 tcgcccacat atagggcata gcaaatttat tgtcgggatc gtgtttggcg accaacttca
    20701 gcagctccgg atcgagattc ttccactccg gcaatttgct tttatccagc ggctggaaaa
    20761 ctcccgctgt cagctggcgc tcaagaaagc ttgctgacgg caccaccaga tcaaagccgg
    20821 tgctccccgc cattaatttg ccttccagta cttcgttaga atcgaaaaca tcatagacga
    20881 ctttaatacc ggtttctttt tcaaagttgg ccaccgtgtc cggggcgata taatcagacc
    20941 agttataaat gtggagtgtt ttttgttcag ccgcgagcgt gctgacagaa acggccatca
    21001 gagcacccgc aaccagaccc gatagccatt ttttatttaa ggcgatcata tctctttcct
    21061 tctgaaaatt cgttaacaaa cgaacaaaag ttgtcacact gaaagatatg caataaacgt
    21121 gcatattttt atcggcgcgg tgtaagaaaa gagaactctc tcccggcctg cactgctcac
    21181 tatataaaag catcgcaaga ataactttag ccagggtttg agactatagc tcggattaaa
    21241 aaacggtatt taacaaattt ttatgcgtat ttgctctatg tgataaagcc aaatcggcac
    21301 aagagaagtg aattaatctt taataaaagg ttaaaatcag cggataattt tgcggcacgc
    21361 agtcactgcg gcagcgactg cgtgctcgaa agaagttatc agtggaggaa atagttttcg
    21421 gtaacgttat tttgcccttc atcgtcagtc ggtaacagca gttgatgggc attagcttca
    21481 agaatgacca tcgaaatctg ctcttcgctc tgacgcacga accatgcaaa ctgctcatag
    21541 gttacgccct gcataacgga taaagactgg caaaccacca gctttggcag attatcatcc
    21601 tgcatatcaa gaaatgcttt cacggtcagc gaactggcat tgatggctga taaatccgcc
    21661 gccagcggca atacggctga aggtcggact tccgccatgg cagaaaacag gatcgtgtta
    21721 tcgatcagat cgattttagc atcaaagaca ccgtcgaaat tctgcatatg gggcagatgc
    21781 agagcctgac agttatcaca ttcaaaaaaa ctcatcccca ggtcatcgag ccattgacgc
    21841 aacgtatcca gaccaggaac gaccagcgat gtcataattt tgtacaacct cttccgataa
    21901 aaagaccggc acagcttacg caaaaagcgc aggcaaaacc atgatcagta atgtgattgc
    21961 gactaaccac ccgttttcag gcaatattct gtcgtagcgt ggcgttcgat ccagcggatc
    22021 attttacccg cgatgtcgat accggtggtt ttttctattc cttccagccc tggcgacgca
    22081 ttcacttcca tcaccaacgg cccgcgatta gcacgcagaa tatccacacc agcaacgtcc
    22141 agcgccatcg ttcgcgcggc ttttatcgcg atttcacgct cctgtggtgt gatactggcg
    22201 acgcttgccg cgccgccacg atgcaaattg gaacgaaaat cgccctcttt cgcccgccgt
    22261 tcaatcgcag cgactacttc atcgccaaca accagacagc ggatatcgca cccttgcgcc
    22321 tctttgatat attcctgcac cagaatatgc gcgttcagac cgcggaaagc gtcaatcacg
    22381 ctttccgccg cctgacgcgt ctccgccagc acgacgccaa ttccctgcgt gccttcaacc
    22441 agcttgacca ccagcggcgc accaccgacc atgtcgatta aatcgctggt atcatccggc
    22501 gaatgcgcaa tgcccgtgac aggcaggtcg atgccctgac gcgccagcag ttgcatggaa
    22561 cgcaatttgt cacgcgcccg ggcaatggcg accgactcat tgagcggata gctccccagc
    22621 atctcgaact ggcgcagtgc cgccgtccca taaaaggtaa tggcggtgcc aatacgcggg
    22681 atcactgcgt caaaatgggg taacttgcgg cctttgtagt gaatagaaga cgccgcagga
    22741 tttatgttca tatagcaaga aagcggatca agaatttcaa ccaggtgacc gcgctgtata
    22801 gcggcttcac gcagccgctt acacgaatag agcgttccat cccgggacaa tatggcaatt
    22861 ttcaccctgc acctctctgt cagacctggt caaaagcccg cgtatcatac atcgacgtgg
    22921 cagttttagc gcgtcgccca accctgtttg tgcaaataat ccagaataaa tgggcggctt
    22981 tctttaatga ttgttcggcg gatatgatcg ctccaggtat cccggcgatt attgctgcca
    23041 cgggtgaggt aatattccgc cagttgctcg tcatactgcg ccagtgcgtc tttatccagc
    23101 ggttgatagc tgttttcatg caccaaaatg gaggccggta aacgcggctt aagatccgga
    23161 ttatccgcag gccagccaag gcacagccca aacagcggca gaacatgctg cggtaatttc
    23221 agcagttccg tcaccgcttc aatattattg cgcaggccgc cgatatatac cccgcccaat
    23281 cccagcgatt ccgctgcggt taatgcattc tgcgccatca ttgccgtatc aacgacaccg
    23341 agcaacagtt gttccgccag gccgagctga gcatccggac agatctgtaa atggcggtta
    23401 aagtcggcac agaacaccca aaactctgcc gcttgcgcta cgtgtttttg cccgccggtc
    23461 agcgtcacca gttcttcacg taacgctttg tcggtaatgc ggataatgct actgcactgc
    23521 aaaaaactgg aactggacgt cgcacgggcg ctgttaataa tcgcctcacg ctgcgcttcg
    23581 gaaatgggtt catcagtgaa atggcgaatg gagcgatggc cacaaataag ttcaatggtt
    23641 ggcgtcatta tctttttctc tttctgaacg tgaatattgc ggtggatggt tcatcagctg
    23701 tggggcaaga cgttttgcca cctgaagaat aaccaccacc gcagcgggaa gcatgagcaa
    23761 aacaccgaga aaaatcatca gaatctgcac ttctggccga gaaaatggct caggtagcga
    23821 cagggagtcg cttaccgaca gcagcgccac cgccagcaac atcattccga taaattccag
    23881 tatcaacacg cttttaggca atttaccgat cgcgcgcata cgcttccctc tgcaaagtga
    23941 gccttcagtc taaaactttt cactgtattg tgtttaacag ttatagcttt tagcaattaa
    24001 tgcaacaggt taaacctact ttcagcgaat acattttagc gtgatcatta caggcataaa
    24061 tctatgagga gagaaataat gcaaaccgtt atttttggtc gtccgggttg cccttactgt
    24121 gtgcgtgcaa aagatctggc tgagaaattg agcaatgaac gcgatgattt ccagtatcag
    24181 tatgtagata ttcgtgcgga agggatcact aaagaagatc tacaacaaaa ggcaggtaaa
    24241 cccgtagaaa ccgtgccgca gatttttgtc gatcagcaac atatcggcgg ctataccgat
    24301 tttgctgcat gggtgaaaga gaatctggac gcctgatcgt ctgacaagcc ctcgcattga
    24361 gggctttatt gattttttct gtgctgtggt ttaaacaaac tactgataaa taagaaacac
    24421 aatgccccca gcgcacacca gaacaccgca cttaataacc atgccagctc ttgccagaat
    24481 gagcgcgtcg gtgaaaaaaa cagccgcata atgagcatcg agcagggtgc cgccagcatt
    24541 gcgccaaaca gaggtttcag gacttctcta cgatgtgaaa agaagctggc aactgcacca
    24601 ggaagaatga aaaatagcaa accgatttca ggatgcccgg cagcccgaaa agcgcctttc
    24661 atgtgcgtcg ccagaaaaag acacaccaca atgaagagga caaaacagca gattgccccc
    24721 gcccaacgtt gtttatgttt cactcgttcc tcctgacact gcgtctatcg aacacatttt
    24781 tcgccagtgt ggcgttcagt aagataaagc cgcttcgcat tccatgctaa tataggccaa
    24841 cgcaattcat atagccgttg atacctaatg tgattacact agtaaaatat attgttactt
    24901 tactatcgtt taggtgcgct gaatgaatct gcgccctgaa ttctggtaaa aacattatcg
    24961 taaattacca tttctttcaa cagcttacta gtaaacaaga agttagcctc cgtgaatata
    25021 aacgtcgccg aattgttaaa tgggaattac attctgttat tatttgtggt cctcgcgctt
    25081 gggctatgtc tcgggaaatt acgacttggt tcgatccaac tgggtaattc cattggcgtt
    25141 ttagtcgtat cgctgttatt aggccaacaa catttcagca ttaacaccga cgcgcttaat
    25201 cttggcttta tgctgtttat tttctgcgtc ggggtcgaag ccggaccgaa ctttttttcc
    25261 attttttttc gcgatgggaa aaattaccta atgttagcac tggtgatggt tggcagtgcg
    25321 ctggtgatcg ccttagggtt aggtaagctg tttggctggg atattggcct gacggccggt
    25381 atgttagctg gctctatgac gtcgacaccg gttctggtcg gtgctggcga tacactgcgt
    25441 cattccggca tggaaagcag gcagctctca ctggcactgg ataatctgag cctcgggtat
    25501 gccttaacct atttaatcgg tctggtgagt ttgattgttg gtgcgcgtta cttgccgaaa
    25561 ttgcagcatc aggacttaca gaccagcgcc cagcaaatcg cccgcgaacg tggcctggac
    25621 actgatgcca accgtaaggt ttatttaccg gtgatccgcg cctaccgcgt cggcccggag
    25681 ctggtggcct ggaccgacgg caaaaatctg cgtgaactgg gtatttatcg acaaactggc
    25741 tgctacattg aacgtattcg acgtaacggg attctggcaa atccagacgg tgatgcggtg
    25801 ctacaaatgg gcgatgaaat agcgttggta ggctatcccg acgcccacgc ccgactcgat
    25861 cccagcttcc gtaacggcaa agaagttttc gatcgtgacc ttctcgacat gcgtatcgtc
    25921 actgaagaag tggtcgttaa aaaccataac gccgttggca aacgtctcgc acaactgaag
    25981 ttgaccgatc acggttgctt ccttaaccgc gtcattcgta gccagattga gatgccgata
    26041 gatgacaacg tcgtgcttaa caaaggtgac gttttacaag tcagcggcga tgcccgtcgc
    26101 gtaaaaacca tcgccgatcg catcggcttt atctcgattc atagccaggt cactgacttg
    26161 ctggcattct gcgccttctt tgttattggg ctgatgatcg ggatgatcac cttccagttc
    26221 agcacattca gtttcggcat gggaaacgct gccgggttgt tattcgccgg aattatgctg
    26281 ggatttatgc gcgctaacca cccgaccttc ggttacattc cgcagggtgc attaagcatg
    26341 gtgaaagagt tcggcttaat ggtgtttatg gcaggcgttg gtctgagcgc cggtagcggt
    26401 attaataacg gcctgggcgc gattggcggt cagatgttga ttgccggatt gattgtcagt
    26461 cttgtgccag tggttatctg tttcttgttc ggtgcttatg tattgcgaat gaaccgcgca
    26521 ctgttgttcg gcgcaatgat gggcgcacgc acctgcgcgc cggcaatgga gatcatcagt
    26581 gatacagctc gcagtaacat cccggcgctg ggctatgcgg gcacctatgc aatcgccaac
    26641 gtcctgctga cgctggcagg gacaatcatc gtcatggtat ggccaggatt aggataaaac
    26701 tgaagttgcc ctgaaaatga aatttttttt gcacaaccgc agaacttttc cgcagggcat
    26761 cagtcttaat tagtgccact gcttttcttt gatgtcccca ttttgtggag cccatcaacc
    26821 ccgccatttc ggttcaaggt tgatgggttt tttgttgcct gaaatttatc tactacccag
    26881 caatcctctc aaccatcctc aaaatctcct cgcgtgatag cggcttacgg tcggtgacaa
    26941 aatgcagcgt cattccctca ataaacgcat caagcgcgcg ggcggttccg ggttcaaacc
    27001 attgttcgag cgtttgttga ctgcgctgca tccagttttg cattaccgtt tttaagagcg
    27061 gttttcggct agccagcgcg tagagctggt acatcagctc catattatcc ggcgttgcga
    27121 cctgtgagct gtagatcata tcggtgatag cctggcatgc gcctggagca tcactaacat
    27181 cgctaaaaaa tgcctgatat tgccgggaca tgatctcagt aaaacggctg aacgcctcca
    27241 gcaacaactc atcaattcct gaaaaatagt aggtcatcga tcccaacggc accccggcaa
    27301 gggtagcaat tttgcggtgt gtaacagcat gtattccgta aagtttcacc gcctccagcg
    27361 tggcctggat aattttttct cgtcgttgcg gatcgttagc gcgacgcatg tcatttcctc
    27421 tctctgcaat tgtgtacaaa tgtacacagt cttgctaatg ttgtcttccc tcttcttatt
    27481 ttgacgtggt ctatgaccgt aaattcttca cgtaatgcat tgaaacgccg aacctgggcg
    27541 ctgtttatgt tcttcttttt gccaggcctg ttaatggcgt cctgggcaac ccgtacgcct
    27601 gctatccgcg atattctctc tgtctcgatc gctgaaatgg gcggtgttct ctttggtctg
    27661 tcgatcggtt cgatgagcgg tattctctgc tcggcgtggt tagtgaaacg ctttgggacg
    27721 cgtaatgtca tccttgtcac gatgtcctgc gcattgatcg ggatgatggt attaagtctg
    27781 gcactctggc tgacatcgcc cttgctcttt gccgttggtc tcggcgtctt tggggctagt
    27841 tttggttctg cggaagtggc gataaacgtt gaaggtgccg ccgttgagag agaaatgaat
    27901 aagacggttt taccgatgat gcacggtttt tatagcctgg gcacgctggc aggcgctggt
    27961 gtcgggatgg cactgacggc ctttggcgtt ccggcaacga tgcacatttt attggcggcg
    28021 ctggtaggca tcgcgcctat ttatatcgcc attcaggcaa tccctgatgg tacgggcaaa
    28081 aatgctgccg atggcaccca gcatggcgaa aaaggcgttc ctttttatcg cgatatccag
    28141 ttgctgttga ttggtgttgt agtgctggcg atggcctttg ccgaaggttc tgccaacgac
    28201 tggttaccct tattaatggt tgatggtcac ggttttagcc ctacttccgg ctcgctgatt
    28261 tatgccggtt ttactctggg gatgaccgtt ggacgcttta ccggcggttg gttcattgac
    28321 cgttacagtc gcgttgccgt ggttcgggcc agtgcactaa tgggggcgtt gggtattggg
    28381 ctgattattt ttgtcgatag cgcctgggtc gctggggtgt ctgttgtact ttggggactg
    28441 ggtgcctcgc tgggcttccc gctgaccatt tctgccgcca gcgataccgg ccccgatgca
    28501 ccaacccgcg tcagcgtggt agctacgacc ggttatctgg ctttcctcgt cgggccgccg
    28561 ctgctgggct atctcggcga acattatgga ttacgtagtg caatgatggt tgtactggcg
    28621 ctggttattc tcgcggctat tgtcgcgaaa gccgtcgcca aacccgatac caaaacgcag
    28681 acggcgatgg agaatagttg atgagcatta aattaattgc ggtagacatg gatggtactt
    28741 tcttaagcga tcaaaaaacc tataaccgtg agcggtttat ggctcagtat cagcaaatga
    28801 aagcacaagg cattcgcttt gtggtcgcca gcgggaatca atattatcag ttgatctctt
    28861 tctttcctga aattgctaat gaaattgcct ttgtggctga aaacggcggc tgggtagtga
    28921 gcgaaggcaa agatgttttt aatggcgagc tgtcgaagga tgcgtttact actgtcgtgg
    28981 aacatttgct gacgcgcccg gaagtggaaa ttattgcctg cggaaaaaat agcgcctata
    29041 ccctcaaaaa atatgacgat gccatgaaaa cggtggcgga aatgtattat caccgtctgg
    29101 aatacgtcga taactttgac aacttagaag atatcttctt taaatttggc cttaatctct
    29161 ctgacgaact gatcccacaa gtgcaaaaag cattacatga ggccatcggc gatatcatgg
    29221 taccggtcca taccggcaac ggcagcatcg atctgattat ccccggtgta cataaagcca
    29281 atggccttcg ccaactgcag aaattatggg gaatagacga cagcgaagtg gtggtctttg
    29341 gcgatggcgg taacgatatt gagatgctgc gtcaggcagg gtttagcttt gcaatggaaa
    29401 atgccggcag cgcggtcgtc gcagcggcaa aataccgggc aggctccaat aaccgtgaag
    29461 gcgtactgga tgtgatcgat aaagtgctta aacacgaagc gccatttaag caataaaaaa
    29521 ggcagcacgc ccggcaacac aatacctgaa tgaaggctgc ataattcgcg gaaattaacc
    29581 cgctgcatta tttcaggcga aatgattatg aaaaattgtc tactgttggg cgcgctttta
    29641 atgggcttta ctggtgtggc gatggcgcaa agtgtcaccg tcgatgtgcc gagtggatac
    29701 aaagtggttg tggttcctga ttcagtcagc gttccacaag cggtcagcgt cgcgactgtg
    29761 ccgcaaaccg tctatgtggc tcctgcgcca gctccggctt accgcccgca tccttatgtt
    29821 cgccatcttg ccagcgtagg tgaagggatg gttatcgaac accagattga cgaccatcac
    29881 cattaattcg acaatgcctg atcgcacaaa gcaatcaggc atttttttac ccttcgtgcg
    29941 aatttcccat ctgtttatct tttaaaaaga taaccatcag cgacagccac aaaatgccgt
    30001 tgacaaggtt gaagagatta aacagtccgt tgcccccgtt cagccaggca tgtttgctga
    30061 tttcaatacc gacggtaaag atcagcattt gcagcatccc catcgccgca gaaaccgtac
    30121 ctttactcat atcgctggca aacagggtta atcgcaccag tcccgcattc gccagaccaa
    30181 taccgaaagc ataaatactt aacccggcgg tcatccataa atacgcgtgc gatgagataa
    30241 ccgttgccgc agcagcgacc aacagaccaa tcataatcgg ccagccgccc ataataatca
    30301 gcgaacgtac ggtgcggcgc gaggtcagac gcgctaacag caagttaccc gcaattaacg
    30361 ccccaaaaat aggcacttgc agcaggccat attcatagct gctcaactgc tcaccggtaa
    30421 taatgataat cggcgactgg gcgatccacg ccagcaacgg caggctaacg aatcccagcg
    30481 ccagcgcccc cgccacaaag cgaccgttct tcagcaccag cttatagtca cgaccgagtt
    30541 ctttcagcga cagtttctcg cctatacgcg tggcggtttc aggcatagct cgttgcagac
    30601 cgaaaaagga gatcgctgcc aatgcggcaa acaagacaaa catcccttcc cagggcagca
    30661 catggatcca cgccgcgccc accagcggac caagtagtgg agcaatcagc gccacgttcg
    30721 ccattagcgc ggtgatcttg atacaaaccg cctcttcgaa ggattcctga attgcggcgt
    30781 atcccacagc gccaatgaaa cagaggctta taccctgcaa gaagcgcaac agggtgaatt
    30841 gttcaatgtt ttgtgccagt aatattgcca gacaggtgac gataaaccac accactcccg
    30901 ccagcatcac cggacggcgg ccaatacgat ccgacaacgg ccccaggagc cattgtaaaa
    30961 acatcccgcc cgccagatac gcagtcatcg aagtaggaac ccaatcaatg cccgcctgat
    31021 attgttccac cacggccaac ataccgggtt gaatcatatc gttgccgata taggttgaaa
    31081 attcgtaaag caccagacag agagggaaaa gtaacgcctg acgtccaagc ctggcaccgg
    31141 aagctaattt attttgcatg caatttcttc gccaataata atcgcgcaaa gtttaataaa
    31201 agcgcagcta acgagaaagc gaattttgta gctgaaacca cggttaagca cattcttaca
    31261 ttattgcgag tatagctacg ctttctttaa gttttattta acctttgccc gttacaatca
    31321 cctaccgtaa acaggccgct tgagggaaat aagacgatgc cgctttaccc agtttaacct
    31381 gcactttatt ctcaacgact tgcctgtatt ggctcccttt taatcacttt gcgtcgggaa
    31441 gttatgctgg aaaatttgaa tctctctcta ttctctctta ttaacgcaac gccagactct
    31501 gcgccgtgga tgatctcgtt ggcgattttt attgctaaag atttgattac cgtggtgccg
    31561 ttgctggccg cagtactttg gttgtggggg cttacagcac aacggcaact ggtgataaaa
    31621 atcgctatcg cgctggcggt cagcctgttt gtgtcctgga cgatgggaca tctttttccg
    31681 cacgaccgac cctttgtcga aaatatcggc tataacttcc tgcatcatgc ggcggatgac
    31741 tcattcccga gcgatcacgg tacggtgatt ttcacctttg cactggcatt tttatgctgg
    31801 catcgcctgt ggtccggctc acttttaatg gtgctggccg tcgtcattgc ctggtcgcgc
    31861 gtttatcttg gcgtccactg gccgctggat atgctcggtg gattgctggc aggtatgatt
    31921 ggctgcctta gcgcccagat tatctggcaa gcgatggggc ataaactcta tcaacgtctg
    31981 caatcgtggt atcgcttctg ttttgcatta ccgatccgca aaggctgggt gcgtgactga
    32041 tctctgctaa aaagtgtagt attgagcggc tcgcttcaat aactattcag agggattatg
    32101 gaaacacgtc gcgaagagcg tatcgggcag ctgctgcaag aattaaaacg cagcgataag
    32161 ttacatctta aagacgccgc cgccctgctt ggggtttcgg agatgacgat tcgtcgcgat
    32221 ctgaacaacc acagtgcgcc cgtcgttttg ctcggcggct atattgttct ggaaccacgc
    32281 agcgccagcc attacctgtt aagcgatcaa aaatcccgcc tggtggaaga aaaacgccgg
    32341 gcggcaaaac tggctgcgac gctggtagaa cccgatcaga ccctcttttt tgactgtggc
    32401 accaccacgc cgtggattat tgaagcaatt gataatgaaa tcccttttac cgccgtttgt
    32461 tattcgctaa atacttttct ggcgctgaaa gagaaacccc attgccgcgc gtttctttgc
    32521 ggtggtgaat ttcacgccag caacgccatt ttcaaaccca tcgattttca gcaaacactg
    32581 aataattttt gcccggatat cgctttttat tccgctgcgg gcgtgcatat cagtaaaggc
    32641 gctacctgtt ttaatcttga agagttgccg gtaaaacact gggccatgtc gatggcgcaa
    32701 aagcatgtgc tggttgtcga ccacagtaaa tttggcaagg tgcgtccggc gcgcatgggt
    32761 gacctgaaac gctttgatat tgttgtgagc gattgttgcc cggaagatga gtatgtgaag
    32821 tacgcgcaga cgcagcgtat taagttgatg tattaatgac gtataaccgg atgacgtttc
    32881 gcgccatccg gttatcagaa gattaagaga accagctgcc gaaccactga tggaatttca
    32941 tcatcacgaa atcccacatc cgaccaaaga atccgccctc ttccacattt tccatcacga
    33001 tcagcggacg ctgctcaatg gatttaccgt taagctggaa atcaatggtg ccgacaacct
    33061 gacctttttt cagcggtgcg gtaagctgcg gttccgttaa cgtataactc gccttcaggt
    33121 ttttcagctg cccacgcggt atggtcactg agcccgcttc gcctgccccg agattcactt
    33181 cgctcttatc accaaaccag acgcgctgag tcacaaatgt ggcatcaggt ttaattggcg
    33241 tcacggtttc aaagaagcgg aaaccccagg tcaataattt ctcagactca ttaaaacgga
    33301 tacggtcagt tttcgccccc agcactacgg agattaaacg catatcgccc tgggtagccg
    33361 aagcaaccag attatatccc gcgcctgccg tggttcctgt cttcatgcca tcaacattca
    33421 gattgctgct ccacagcaga cgattacggt taggctgacg aattttgttg aaggtgaact
    33481 ctttctcttt atgaatggcg tactcttccg gcacatcgtg gatcaatgct ttacccagca
    33541 atgccatatc gcgcgcggta ctgaactgcc ccggcgcatc caggccgtgc accgtctgga
    33601 aggtagtgtt ggtcagaccc agttttttgg cataaccatt catcaaacca ataaatgact
    33661 cctggctccc ggcaacgtaa tcagccagcg caatacaggc gtcattaccg gactggataa
    33721 tcacaccttt gttcaagtct gccaccgaaa cctgatcgcc cggtttgagg aacattaccg
    33781 atgaaccacg cagtgccgga tttcccgtcg cccaggcatc tttaccgacc gtcaccatat
    33841 cggtgagttt aattttatcg gccttaagcg cctgcccaac cacatagctg gtcataattt
    33901 tagtcaggct cgcgggatcc agtttctcat ccgcattgcc ttctgccagc actttaccgc
    33961 tggcgtaatc cattaaaatc catgcacggg catccacgct cggcgcttca acggtttgtt
    34021 ccgccgcgaa tgccgttggg gcaaaaagga ataaaaatgc agaacccgct gcaagaccac
    34081 gaaggagaga ggagtattgc gtcataaatg ccacccgagt atccattcaa aaaaaatacg
    34141 ttatatcgcc gtatgataag ttcggtgatt aataacgcac acacaaactt aaagaaaccg
    34201 taagttggta aagtttttaa agtttatgca atatcctgcc gcttcgctgc ttctggtgtc
    34261 atttttttgc cagctgttgc ttaaaagtta actttacttc accatcggag tcctgtttag
    34321 cctgtggctg cctgtcggaa aaggggtgag tatgattacg ctgtggggtc ggaataattc
    34381 aaccaacgta aaaaaagtat tgctgacgct cgaagaactg gaactacctt atgagcaaat
    34441 tctcgcgggc cgtgagtttg ggataaatca cgatactgat tttctggcga tgaaccctaa
    34501 cgggctggtg ccgttgttgc gtgacgacga aagtgatctc attctttggg aatcaaacgc
    34561 cattgtccgc tatctggcgg cacagtacgg gcaaaaacgc ctgtggatcg actcaccggc
    34621 acgtcgtgcg gaagcagaaa aatggatgga ctgggcaaac cagacgctca gtaatgctca
    34681 tcgcgggatc ctgatgggat tagtcagaac accaccggaa gagcgcgatc aggccgccat
    34741 tgatgccagt tgcaaagagt gcgacgccct gtttgccctg ctcgatgcgg aattggcaaa
    34801 agtaaaatgg ttctcaggcg acgagtttgg tgtgggcgat atcgctatcg caccgttcat
    34861 ctacaatttg tttaacgttg gcctgacctg gacaccgcgt ccaaatctgc aacgctggta
    34921 tcagcaactc actgaacgcc ccgcagtgcg caaagtggtg atgattcccg ttagctaatt
    34981 gcgtgggcta actttaagta attccccact ggactcgtcg gtgagaacgt ataaataacc
    35041 gtcgggtcca gtgcgaacat cacgaattcg ttgccctctg tccgttaaaa tacggccatc
    35101 ttctgtcact ttgtcgccgt tgacgctcat cacaatgaca tctttatctt tcagcgcgcc
    35161 aataaataat ttttgctgcc actgggggaa tttgtcgctg ttatagaaag ccatgccgct
    35221 cacggcgggc gaatctttcc agtaaaaaac aggttgctcg gtcccggcga cgatctcccc
    35281 tttcgcttcc ggtatcttaa agcccgaata gttgattccc caggttgcca gcggccagcc
    35341 gtagtttttg cctttttgcg gaatattaat ttcatcacca ccgcgcgggc catgttcatt
    35401 cagccatagt gcattactcc acggattcat cgccattcct tgcggattac gaatgccata
    35461 agaccagatc tcggcgcgca caccggattc ctttataaaa ggattatcat ccgggatttc
    35521 tcccaggtcg gtcagacgca ccagtttgcc ctgtaattta tccagatcct gcgccgtcgg
    35581 gcgctgattg ttttcgccca gagcaataaa aagataacct ttaccgtcaa ataccatccg
    35641 cccgccaaaa tggttgccgg tagacagttt tggcatctga cgaaagacgg tgcggaagtc
    35701 ggtcactttt gagagatcat cacttaagcg accataaccc acagcagttc cggctttgcc
    35761 atcatcgcca acttcggaat aacttaacca gatgcggcgc gactgagcaa aatcgggcgc
    35821 taaaaccacg tccagcaggc cgccctgccc gtgcgcccaa acgtccggca ctccggaaag
    35881 cggcgcagat aatccttttc ctgcttgcca gtgacgcaac tcgccgccgc gcagagtgat
    35941 taacataccg tgattatcgg gtaaaaaggc cagcgcccag ggatggtcga gtttgtcttg
    36001 cagtacttcg acatttaccg ttgcaggagc cgcccagaga gcggaagaaa gacaaataag
    36061 gggcacaagg aaaaaggatt gtcgatgcat aacgcctccg gattgactct ggcttaaagc
    36121 gtagtcagtg gaggagagaa caaattcatt tttacaaaaa cttaaacatg aagggggaga
    36181 cgctttctcc cccttagttt tcaggccttc tcaagcatgg cgtgcttctg caggctctgg
    36241 atactcagcg ttaagctcat cagacaattt tcaagcttat cggcgttgac ggtaataaca
    36301 gtcgggcaat catggtgccc actcatcaaa catactgcgg ctgtcgctaa tgcttcttca
    36361 gcatgatgaa gagcactcca ctcttcctga tccagatgaa gattcaaccg cagcgattta
    36421 tcgtgcagtt cgcgattcag tttaaaaaag ttatctcgta gatgattgct ttcgctgacg
    36481 gacatgtatc cttttgcctt cctcagttgc acgtatgcgg cgaggtcaac gcgtgcgtcg
    36541 atcaaccggt tcagcaggtc gattcgctgt ctgtcaacga acatacttcg atcctcctct
    36601 ttccagcctt gttgcaatta aatagtatgg ctgttttttg agcaaaatgc tgtccaggat
    36661 caattcttca cgccgaatta acaaaattta catttccttc aactccgcca gcgaatgaga
    36721 ttgcgataca aattttatcc agaactctgt agaatccctg ccctgacctt tcctgtaact
    36781 gaatattttt taagctatga gcaaagtaac tccccagccg aaaatcggct ttgtttccct
    36841 tggctgcccg aaaaaccttg tcgattcaga gcgtattctc accgaactac gcactgaagg
    36901 ttatgacgtg gtaccgagct atgacgatgc ggacatggtg atcgtcaaca cctgcggctt
    36961 tattgacagc gcggtacaag aatcactgga agccattggt gaagcgttga atgaaaacgg
    37021 caaggtaatt gtgaccggtt gtctgggggc aaaagaagat cagatccgcg aagtccaccc
    37081 gaaagtgctg gaaatcaccg ggcctcatag ctatgagcag gttctggagc acgttcatca
    37141 ctacgtgcca aaaccgaaac acaacccgtt cctgagcctg gtgccagaac aaggtgtgaa
    37201 actgacgccg cgtcattatg cttatctgaa aatttctgaa ggctgtaatc accgctgcac
    37261 cttctgcatt attccgtcta tgcgcggcga tctggtgagc cgtccgattg gcgaagtgtt
    37321 aagtgaagcg aaacgtctgg ttgatgcggg cgttaaagaa attctggtga tctcgcagga
    37381 tacttccgcg tatggcgtcg atgttaaaca tcgtactggc ttccacaacg gcgagccggt
    37441 aaaaaccagc atggtcagcc tgtgcgaaca gttatcgaaa ctggggatct ggacacgtct
    37501 gcactacgtt tacccttatc cgcatgtgga cgacgtcatc ccactgatgg cagagggcaa
    37561 aatcctgccg tatctggaca ttccgttgca gcacgccagc ccgcgcattc tcaaactgat
    37621 gaagcgtccg ggttctgtag atcgccaact ggcgcgcatc aaacagtggc gcgaaatctg
    37681 cccggaactg accctacgct caacctttat tgttggcttc cctggcgaga cggaagaaga
    37741 tttccagatg ctactcgact tcctgaaaga agcacgtctg gatcgcgttg gctgctttaa
    37801 atacagcccg gttgaaggtg cagacgccaa tgccctgcct gaccaggttc cggaagaagt
    37861 gaaagaagaa cgctggaacc gtttcatgca gctgcagcag cagatttccg ccgagcgcct
    37921 gcaagagaaa gtgggtcgtg aaattctggt gattatcgac gaagtggacg aagaaggcgc
    37981 gattggtcgc agcatggcag atgcaccgga aatcgacggc gcggtttatc tcaatggtga
    38041 aaccaacgtt aagccgggtg atatcctgcg agtgaaagtc gagcacgccg atgagtacga
    38101 tttgtggggt agccgggttt aattaattca ggccgggcaa aatcatttgt ccggcctgcg
    38161 aataatgatt actgccagct aatctgcgcc ctgccgtttt tcttactctt atacagccgc
    38221 tcatccgcca gcattttcaa tcgttcgacg gtagtacatt catttgaatg cgctacaccg
    38281 atactggtgc ttaaattaat gcttcccacc tggaaatgaa cgatttcttt tagaatcgat
    38341 agcaactctt ccagcgtgcc gccagtataa atcaccgcaa attcgtcacc tccgaagcgg
    38401 tagactttac ctttatctac cgggatctgt gatttaagga ttttcaccac tttcatcaac
    38461 acttcatcgc ccagcaaatg accgaaggtg tcgttaatgt ttttgaattt atcgacgtca
    38521 aacaggcaca aataaccgcc tttttccggc agcgctttta aatcttcgtc aaaggatttt
    38581 ctgcccatcg ctttggtcag gtcgtccagg aatgccgagt tatacatact gtagagtttt
    38641 ttgacatcgg cagccgaaaa gaaaagcccg ccatccagta cgcgttcaaa atggttatta
    38701 ataatggctt ctttctccac aataccacga ttaatcactc tgcgtaccag atagaggcaa
    38761 ctggcacccg atatcactgc caccaatgcg gcaaagaaaa taatcaatgt acatacctga
    38821 aaataaacgt cttttttata agcaaatacg tacaatccgg tcggcaaata ggagaagtgc
    38881 tccattgctt ccgaaacggt gaagatggcg tttttagcgt tatattcatc accggtcacc
    38941 gatttaccgt tcttgaacag ggagaacatc aggttctcgc tatccatcgc cagcgatttt
    39001 gacagtaaag aaaaacgttc cagaccaagc aaaaatatca gactacgatt gtgagttacc
    39061 ggatagaggt aatagacgaa ggttttacca tcaaaagaga taaaccctgt atttttgaca
    39121 tgtcgatact taacaacctg cataatatct gcacaataat ttttctcaaa ctcctttacc
    39181 tgaatacatt cgtcactgga aatcagataa ggaccgacat cgtacaaata agagggtgaa
    39241 accgagtcgg cgtaagctgt gcgtaagcca accaacagct gttcctccgt aggatttagc
    39301 gtgttgatca gatcaattgc cacactccgc cgatattcag caatatttgc caccgcaaaa
    39361 gcagtatcaa taacggactg tttcaggcca tacacccgtt cctttaccat ttgagtgtag
    39421 atcccgcagg caactgctga aatcatgata aaaatcagca gactgactgt aagtacgaat
    39481 ttattgattc tggacatacg taaactactc ttttactaat tttccacttt tatcccaggc
    39541 ggagaatggc atgggtttct ggtacagata cccctgagcc tgaacacatc ctaatttgat
    39601 taattcacgc gcaacgtctt cgctctctac gccttccgca atcaccggga tccggttata
    39661 gcgtgccaga tcgaaaataa tgcgcacaat ttttcccgca gtaccgaaaa tatcgccggt
    39721 aaattgcgaa tccaccttta tactgtctgg attaatttca taaaaacgtt tcaggtttga
    39781 caaaccggtg ccaaagtcat caatcgatac ccgtacccct tgtttacgca gttgttcaat
    39841 attgagatag aaatgttcat taattcgctc gatcacggtt tcggtgatct caacacaaag
    39901 gctgttcgcc ttcaggccat tttctttcat gatggtagta aaacgctcat gaaagtgtgg
    39961 ttcgtttaac tgccagggcg aaacattaat atgcagtaag aaatcatcct tcagcgacgc
    40021 acgctgacta aaatgtctga attcacccat cgcggtttta ataatttgat agcccagctc
    40081 attgataaac ccgatatctt cagcaatggt aatgaacttc agcggtgaaa taatcccccg
    40141 ctccgcagac acccaacggc acaacgcctc cgcgcccaaa atggtgcggg tgttaatatc
    40201 aacaatcggt tgatagacca ggaatagttc gccaatttcc attgcatggc gaatattacg
    40261 cgcaatccag atattctctt ctatttcgtt gagtttcgca tcatcacaga aaataaactc
    40321 tgagaacata tggttgcgga tactggaaat cgccagtttc agcttttctg cgtaactcca
    40381 ggcgttttcc ccctgcaaag gttcacaaat agcagactta tggatgcgca gattgcggta
    40441 gccaaaactg ctgtcaaaat cgtttaccgt cgctatctta cgggtaaacg tctgtacatt
    40501 ttcccggcac aggagtaaat agagatcggc attaaatgtc acgatatcgc agcattgcgc
    40561 atatttctcg gcaattcgct gacacaattt cctgacgatt ttattgcgtt catcaacacc
    40621 aaacaccgct tccacagctt ccagaccaca cagtttgatg atccccacag ccagatactg
    40681 attattgttg gactcaataa tcgccatatt tttaataaaa ccgctttcct gatcgtaaga
    40741 gatcagcgag agcaatttat ttgcccgttc aatttcagca tctttcattt ccgcgatcga
    40801 atttttgatg ctgataatct ctttcgcatc gccttcacga atcttcaggg cctcgatttg
    40861 atccgtagag tcaggcaaaa acgccagcgt attgaccaaa tctgtcattt cagaaaattg
    40921 acgacggaaa actcgagtgg tcattaaata aaccaccagc aatacgataa taatgaaagc
    40981 aaacggcaga taaaaaagtt tatctgatgc gttcaataaa ttaccaccag gataataaaa
    41041 atagatttcg aata
//
LOCUS       DAPOXO010000040        40770 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPOXO010000040 DAPOXO010000000
VERSION     DAPOXO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40770
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.040"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(263..352)
                     /locus_tag="ROH59_002517"
     tRNA            complement(263..352)
                     /locus_tag="ROH59_002517"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(316..318),aa:Ser,seq:cga)
     gene            446..1243
                     /gene="mtfA"
                     /locus_tag="ROH59_002518"
     CDS             446..1243
                     /gene="mtfA"
                     /locus_tag="ROH59_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HDX4804987.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVALAE
                     RFLQQKRLVPLQGFELNSLRSCRIALLFCLPVLELGLEWLDGFHEILIYPAPFVVDDE
                     WEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFISLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH"
     gene            1344..1419
                     /locus_tag="ROH59_002519"
     tRNA            1344..1419
                     /locus_tag="ROH59_002519"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1377..1379,aa:Asn,seq:gtt)
     gene            1581..2843
                     /locus_tag="ROH59_002520"
     CDS             1581..2843
                     /locus_tag="ROH59_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX4804988.1"
                     /translation="MSLTSAKIRTLKPSDKPFKVSDSHGLYLRVKPGGSRHWYLKYRI
                     SGKESRIALGTYPAISLSDARQQREGIRKMLALNINPVQQRAAVRGSRTPEKVFKNVA
                     LAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
                     ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGA
                     YHQGRELTRHAVLLMLHVFIRSSELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRG
                     AKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMCENTVNKALRVMGYD
                     TKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAM
                     MQWWSDYLEACRESYAPPYTIGKNKFIP"
     gene            complement(3037..4341)
                     /gene="ybtS"
                     /locus_tag="ROH59_002521"
     CDS             complement(3037..4341)
                     /gene="ybtS"
                     /locus_tag="ROH59_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salicylate synthase
                     YbtS"
                     /protein_id="HDX4804989.1"
                     /translation="MKISEFLHLALPEEQWLPTISGVLRQFAEEECYVYERQPCWYLG
                     KGCQARLHINADGTQATFIDDAGEQKWAVDSIADCARRFMAHPQVKGRRVYGQVGFNF
                     AAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGCRRLCEWVKEAGTTTQ
                     NAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQA
                     NTPVRSFMFRQEGREALGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELL
                     HDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENK
                     DAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRS
                     VFQDSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV"
     gene            complement(4369..5649)
                     /gene="ybtX"
                     /locus_tag="ROH59_002522"
     CDS             complement(4369..5649)
                     /gene="ybtX"
                     /locus_tag="ROH59_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin-associated zinc MFS transporter
                     YbtX"
                     /protein_id="HDX4804990.1"
                     /translation="MSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALV
                     RAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAI
                     LTIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWG
                     NSVQVGGSYLGMMCGGGVFMMLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATI
                     PHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGN
                     IAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMMAPGHLLLQILQCLV
                     IVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGY
                     AACFLFAGAFTLLAAWVAYIRLHSARELMTSAID"
     gene            complement(5642..7444)
                     /gene="ybtQ"
                     /locus_tag="ROH59_002523"
     CDS             complement(5642..7444)
                     /gene="ybtQ"
                     /locus_tag="ROH59_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtQ"
                     /protein_id="HDX4804991.1"
                     /translation="MKDNNPADNLAWRVIWRQLISSVGSQARMLRRSMLALLLAAFMQ
                     GIAFACLYPIIDALLRGDAPQLLNWAMAFSVAAIVTLVLRWYGLGFEYRGHLAQATHE
                     LRLRLGEQLRRVPLEKLQRGRAGEMNALLLGSVDENLNYVIAIANILLLTIVTPLTAS
                     LATLWIDWRLGLVMLLIFPLLVPFYYWRRPAMRRQMQTLGEAHQRLSGDIVEFAQGMM
                     VLRTCGSDADKSRALLAHFNALENLQTRTHRQGAGATMLIASVVELGLQVVVLSGIVW
                     VVTGTLNLAFLIAAVAMIMRFAEPMAMFISYTSVVELIASALQRIEQFMAIAPLPVAE
                     QSEMPERYDIRFDNVSYRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTTVTKLLM
                     RYADPQQGQISIGGVDIRRLTPEQLNSLISVVFQDVWLFDDTLLANIRIARPQATRQE
                     VEEAARAAQCLEFISRLPQGWLTPMGEMGGQLSGGERQRISIARALLKNAPVVILDEP
                     TAALDIESELAVQKAIDNLVYNRTVIIIAHRLSTIAGAGNILVMEEGQVVEQGTHAQL
                     LSHHGRYQALWQAQMAARVWRDDGVSASGEWGHE"
     gene            complement(7431..9143)
                     /gene="ybtP"
                     /locus_tag="ROH59_002524"
     CDS             complement(7431..9143)
                     /gene="ybtP"
                     /locus_tag="ROH59_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtP"
                     /protein_id="HDX4804992.1"
                     /translation="MALAGLAALTSLGALLFLAWSLRDIRATPDAIPAWPLGGVIGCV
                     VLTFVLRLQAFNTSHYAAFHLENILRSRLARKALQLPPGVLQQMGSGSVAKVMLDDVK
                     SLHIFVADSTPLYARAIIMPLATIVILFWLDWRLAIATLGVLAFGSVVLVLARQRSED
                     MAQRYHKAREQVSAAVIEFVQAMPVVRTFDSGSTSFLRYQRALEEWVDVLKTWYRKAG
                     FSARFSFSILNPLPTLFVLIWSGYGLLHYGSFDFIAWVAVLLLGSGMAEAVMPMMMLN
                     NLVAQTRLSIQRIYQVLAMPELSLPQSDQQPQEASITFEQVSFHYPQARTGAALQEVS
                     FHVPAGQIVALVGPSGAGKSTVVRLLLRYADPDKGHIRIGGVDLRDMQTDTLMKQLSF
                     VFQDNFLFADTIANNIRLGAPDTPLEAVIAAARVAQAHDFISALPEGYNTRVGERGVF
                     LSGGQRQRITIARALLQDRPILVLDEATAFADPENEAALIKALAAAMRGRTVIMVAHR
                     LSMVTQADVILLFSDGQLREMGNHTQLLAQGGLYQRLWQHYQQAQHWVPGGTQEEVME
                     NERQ"
     gene            9400..10359
                     /gene="ybtA"
                     /locus_tag="ROH59_002525"
     CDS             9400..10359
                     /gene="ybtA"
                     /locus_tag="ROH59_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin transcriptional regulator YbtA"
                     /protein_id="HDX4804993.1"
                     /translation="MTESPQTQSEISIHQLVVGKPANDGNIPAQCELLRCSLQEGMDI
                     LLWRGHFARPETLQLHDDLGRINFSCILEGTSRFAIQGLRRHTDWELARNRHYITHTP
                     DCRGSASYCGRFESITLSFSPETLALWVPDISAVIKNKIDSHCCCQQHRCNAETHLTA
                     QALRHALMRMHSGFSHEQKPSTLWLQGQSLVMLSLVLDEHREDASCLSCHFTPMERQK
                     LLRAKDLLLADLTQAPGVAELARESGLSVLKIKRGFRVLFNNSVYGLFQAERMQEARR
                     RLANGNTSVMTVAADLGYANASHFSAAFQKQFGVTPSTFKRGM"
     gene            10550..16657
                     /gene="irp2"
                     /locus_tag="ROH59_002526"
     CDS             10550..16657
                     /gene="irp2"
                     /locus_tag="ROH59_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin non-ribosomal peptide synthetase
                     HMWP2"
                     /protein_id="HDX4804994.1"
                     /translation="MISGAPSQDSLLPDNRHAADYQQLRERLIQELNLTPQQLHEESN
                     LIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTLAAWNQLMLSRSPENAEEETPPD
                     ESSWPNMTESTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFEGHCLTASQLEQAIT
                     TLLQRHPMLHIAFRPDGQQVWLPQPYWNGVTVHDLRHNDAESRQAYLDALRQRLSHRL
                     LRVEIGETFDFQLTLLPDNRHRLHVNIDLLIMDASSFTLFFDELNALLAGESLPAIDT
                     RYDFRSYLLHQQKINQPLRDDARAYWLAKASTLPPAPVLPLACEPATLREVRNTRRRM
                     IVPATRWHAFSNRAGEYGVTPTMALATCFSAVLARWGGLTRLLLNITLFDRQPLHPAV
                     GAMLADFTNILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQRYP
                     HGAPVVFTSNLGRSLYSSRAESPLGEPEWGISQTPQVWIDHLAFEHHGEVWLQWDSND
                     ALFPPALVETLFDTYCQLINQLCDDESAWQKPFADMMPASQRAIRERVNATGAPIPEG
                     LLHEGIFRIALQQPQALAVTDMRYQWNYHELTDYARRCAGRLIECGVQPGDNVAITMS
                     KGAGQLVAVLAVLLAGAVYVPVSLDQPAARREKIYADASVRLVLICQHDASAGSDDIP
                     VLAWQQAIEAEPIANPVVRAPTQPAYIIYTSGSTGTPKGVVISHRGALNTCCDINTRY
                     QVGPHDRVLALSALHFDLSVYDIFGVLRAGGALVMVMENQRRDPHAWCELIQRHQVTL
                     WNSVPALFDMLLTWCEGFADATPENLRAVMLSGDWIGLDLPARYRAFRPQGQFIAMGG
                     ATEASIWSNACEIHDVPAHWRSIPYGFPLTNQRYRVVDEQGRDCPDWVPGELWIGGIG
                     VAEGYFNDPLRSEQQFLTLPDERWYRTGDLGCYWPDGTIEFLGRRDKQVKVGGYRIEL
                     GEIESALSQLAGVKQATVLAIGEKEKTLAAYVVPQGEAFCVTDHRNPALPQAWHTLAG
                     TLPCCAISPEISAEQVADFLQHRLLKLKPGHTAGADPLPLMNSLAIQPRWQAVVERWL
                     AFLVTQRRLKPAAEGYQVCAGEEREDEHPHFSGHDLTLSQILRGARNELSLLNDAQWS
                     PESLAFNHPASAPYIQELATICQQLAQRLQRPVRLLEVGTRTGRAAESLLAQLNAGQI
                     EYVGLEQSQEMLLSARQRLAPWPGARLSLWNADTLAAHAHSADIIWLNNALHRLLPED
                     PGLLATLQQLAVPGALLYVMEFRQLTPSALLSTLLLTNGQPEALLHNSADWAALFSAA
                     GFNCQHGDEVAGLQRFLVQCPDRQVRRDPRQLQAALAGRLPGWMVPQRIVFLDALPLT
                     ANGKIDYQALKRRHTPEAENPAEADLPQGDIEKQVAALWQQLLSTGNVTRETDFFQQG
                     GDSLLATRLTGQLHQAGYEAQLSDLFNHPRLADFAATLRKTDVPVEQPFVHSPEDRYQ
                     PFALTDVQQAYLVGRQPGFALGGVGSHFFVEFEIADLDLTRLETVWNRLIARHDMLRA
                     VVRDGQQQVLEQTPRWVIPAHILHTPEEALQVREKLAHQVLNPEVWPVFDLQVGYVDG
                     MPARLWLCLDNLLLDGLSMQILLAELEHGYRYPQQLLPPLPVTFRDYLQQPSLQSPNP
                     DSLAWWQAQLDDIPPAPALPLRCLPQEVETPRFARLNGALDSTRWHRLKKRAADAHLT
                     PSAVLLSVWSTVLSAWSAQPEFTLNLTLFDRRPLHPQINQILGDFTSLMLLSWHPGES
                     WLHSAQSLQQRLSQNLNHRDVSAIRVMRQLAQRQNVPAVPMPVVFTSALGFEQDNFLA
                     RRNLLKPVWGISQTPQVWLDHQIYESEGELRFNWDFVAALFPAGQVERQFEQYCALLN
                     RMAEDESGWQLPLAALVPPVKHAGQCAERSPRVCPEHSQPHIAADESTVSLICDAFRE
                     VVGESVTPAENFFEAGATSLNLVQLHVLLQRHEFSTLTLLDLFTHPSPAALADYLAGV
                     ATVEKTKRPRPVRRRQRRI"
     gene            16745..26236
                     /gene="irp1"
                     /locus_tag="ROH59_002527"
     CDS             16745..26236
                     /gene="irp1"
                     /locus_tag="ROH59_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin polyketide synthase HMWP1"
                     /protein_id="HDX4804995.1"
                     /translation="MDNLRFSSAPTADSIDASIAQHYPDCEPVAVIGYACHFPESPDG
                     ETFWQNLLEGRECSRRFTREELLAVGLDAAIIDDPHYVNIGTVLDNADCFDATLFGYS
                     RQEAESMDPQQRLFLQAVWHALEHAGYAPGAVPHKTGVFASSRMSTYPGREALNVTEV
                     AQVKGLQSLMGNDKDYIATRAAYKLNLHGPALSVQTACSSSLVAVHLACESLRAGESD
                     MAVAGGVALSFPQQAGYRYQPGMIFSPDGHCRPFDASAEGTWAGNGLGCVVLRRLRDA
                     LLSGDPIISVILSSAVNNDGNRKVGYTAPSVAGQQAVIEEALMLAAIDDRQVGYIETH
                     GTGTPLGDAIEIEALRNVYAPRPQDQRCALGSVKSNMGHLDTAAGIAGLLKTVLAVSR
                     GQIPPLLNFHTPNPALKLEESPFTIPVSAQAWQDEMRYAGVSSFGIGGTNCHMIVASL
                     PDALNARLPNTDSGRKSTALLLSAASDSALRRLATDYAGALRENADASSLAFTALHAR
                     RLDLPFRLAAPLNRETAEALSAWAGEKSGALVYSGHGASGKQVWLFTGQGSHWRTMGQ
                     TMYQHSTAFADTLDRCFSACSEMLTPSLREAMFNPDSAQLDNMAWAQPAIVAFEIAMA
                     AHWRAEGLKPDFAIGHSVGEFAAAVVCGHYTIEQVMPLVCRRGALMQQCASGAMVAVF
                     ADEDTLMPLARQFELDLAANNGTQHTVFSGPEARLAVFCATLSQHDINYRRLSVTGAA
                     HSALLEPILDRFQDACAGLHAEPGQIPIISTLTADVIDESTLNQADYWRRHMRQPVRF
                     IQSIQVAHQLGARVFLEMGPDAQLVACGQREYRDNAYWIASARRNKEASDVLNQALLQ
                     LYAAGVALPWADLLAGDGQRIAAPCYPFDTERYWKERVSPACEPADAALSAGLEVASR
                     AATALDLPRLDALKQCATRLHAIYVDQLVQRCTGDAIENGVDAMTIMRRGRLLPRYQQ
                     LLQRLLNNCVVDGDYRCTDGRYVRARPIEHQQRESLLTELAGYCEGFQAIPDTIARAG
                     DRLYEMMSGAEEPVAIIFPQSASDGVEVLYQEFSFGRYFNQIAAGVLRGIVQTRQPRQ
                     PLRILEVGGGTGGTTAWLLPELNGVPALEYHFTDISALFTRRAQQKFADYDFVKYSEL
                     DLEKEAQSQGFQAQSYDLIVAANVIHATRHIGRTLDNLRPLLKPGGRLLMLEITQPMR
                     LFDFVFGPLVLPLQDLDAREGELFLTTAQWQQQCRHAGFSKVAWLPQDGSPTAGMSEH
                     IILATLPGQAVSAVTFTAPSEPVLGQALTDNGDYLADWSDCAGQPERFNARWQEAWRL
                     LSQRHGDALPVEPPPVAAPEWLGKVRLSWQNEAFSRGQMRVEARHPAGEWLPLSPAAP
                     LPAPQTHYQWRWTPLNVASIDHPLTFSFSAGTLARSDELAQYGIIHDPHASSRLMIVE
                     ESEDTLALAEKVIAALTASAAGLIVVTRRAWRVEENEALSASHHALWALLRVAANEQP
                     ERLLAAIDLAENTPWETLHQGLSAVSLSQRWLAARGDTLWLPSLTPNTGCAAELPANV
                     FTGDSRWHLVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCRC
                     DVGDAGQLATVLDDLAANGGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQL
                     LQTLRNHDGRYLILYSSAAATLGAPGQSAHALACGYLDGLAQQFSTLDAPKTLSVAWG
                     AWGESGRAATPEMLATLASRGMGALSDAEGCWHLEQAVMRGAPWRLAMRVFTDKMPPL
                     QQALFNISATEKAATPVIPPADDNAFNGSLSDETAVMAWLKKRIAVQLRLSDPASLHP
                     NQDLLQLGMDSLLFLELSSDIQHYLGVRINAERAWQDLSPHGLTQLICSKPEATPAAS
                     QPEVLRHDADERYAPFPLTPIQHAYWLGRTHLIGYGGVACHVLFEWDKRHDEFDLAIL
                     EKAWNQLIARHDMLRMVVDADGQQRILATTPEYHIPRDDLRALSPEEQRIALEKRRHE
                     LSYRVLPADQWPLFELVVSEIDDCHYRLHMNLDLLQFDVQSFKVMMDDLAQVWRGETL
                     APLAITFRDYVMAEQARRQTSAWHDAWDYWQEKLPQLPLAPELPVVETPPETPHFTTF
                     KSTIGKTEWQAVKQRWQQQGVTPSAALLTLFAATLERWSRTTTFTLNLTFFNRQPIHP
                     QINQLIGDFTSVTLVDFNFSAPVTLQEQMQQTQQRLWQNMAHSEMNGVEVIRELGRLR
                     GSQRQPLMPVVFTSMLGMTLEGMTIDQAMSHLFGEPCYVFTQTPQVWLDHQVMESDGE
                     LMFSWYCMDNVLEPGAAEAMFNDYCAILQAVIAAPESLKTLASGIARHIPRRRWPLNA
                     QADYDLRDIEQATLEYPGIRQARAEITEQGALTLDIVMADDPSPSAAMPDEHELTQLA
                     LPLPEQAQLDELEATWRWLEARALQGIAATLNRHGLFTTPEIAHRFSAVVQALSAQAS
                     HQRLLRQWLQCLTEREWLIREGESWRCRIPLSEIPEPQEACPQSQWSQALAQYLETCI
                     ARHDALFSGQCSPLELLFNEQHRVTDALYRDNPASACLNRYTAQIAALCSAERILEVG
                     AGTAATTAPVLKATRNTRQSYHFTDVSAQFLNDARARFHDESQVSYALFDINQPLDFT
                     AHPEAGYDLIVAVNVLHDASHVVQTLRRLKLLLKAGGRLLIVEATERNSVFQLASVGF
                     IEGLSGYRDFRRRDEKPMLTRSAWQEVLVQAGFANELAWPAQESSPLRQHLLVARSPG
                     VNRPDKKAVSRYLQQRFGTGLPILQIRQREALFTPLHAPSDAPTEPAKPTPVAGGNPA
                     LEKQVAELWQSLLSRPVARHHDFFELGGDSLMATRMVAQLNRRGIARANLQDLFSHST
                     LSDFCAHLQAATSGEDNPIPLCQGDGEETLFVFHASDGDISAWLPLASALNRRVFGLQ
                     AKSPQRFATLDQMIDEYVGCIRRQQPHGPYVLAGWSYGAFLAAGAAQRLYAKGEQVRM
                     VLIDPVCRQDFCCENRAALLRLLAEGQTPLALPEHFDQQTPDSQLADFISLAKTAGMV
                     SQNLTLQAAETWLDNIAHLLRLLTEHTPGESVPVPCLMVYAAGRPAHWTPAETEWQGW
                     INNADDAVIEASHWQIMMEAPHVQACAQHITRWLCATSTQPENTL"
     gene            26233..27333
                     /gene="ybtU"
                     /locus_tag="ROH59_002528"
     CDS             26233..27333
                     /gene="ybtU"
                     /locus_tag="ROH59_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis oxidoreductase YbtU"
                     /protein_id="HDX4804996.1"
                     /translation="MMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSA
                     RSRELAHAFGIPLYTSPEQITRMPDIACIVVRSTVAGGTGTQLARHFLTRGVHVIQEH
                     PLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLRDAQQLRRCLAKTPQVVHATT
                     SRQLLYSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDD
                     PDMHSLIMHRLLLGWPEGHLSLEASYGPVIWSSSLFVADHQENAHSLYRRPEILRDLP
                     GLTRSAAPLSWRDCCETVGPEGVSWLLHQLRSHLAGEHPPAACQSVHQIALSRLWQQI
                     LRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL"
     gene            27330..28133
                     /gene="ybtT"
                     /locus_tag="ROH59_002529"
     CDS             27330..28133
                     /gene="ybtT"
                     /locus_tag="ROH59_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis thioesterase YbtT"
                     /protein_id="HDX4804997.1"
                     /translation="MTQSAMCIPLWPARNGNTAHLVMCPFAGGSSSAFRHWQAEQLAD
                     CALSLVTWPGRDRLRHLEPLRNITQLAALLANELEASVSPDTPLLLAGHSMGAQVAFE
                     TCRLLEQRGLAPQGLIISGCHAPHLHSERQLSHRDDADFIAELIDIGGCSPELRENQE
                     LMSLFLPLLRADFYATESYHYDSPDVCPPLRTPALLLCGSHDREASWQQVDAWRQWLS
                     HVTGPVVIDGDHFYPIQQARSFFTQIVRHFPHAFSAMTAWQKQPSTSER"
     gene            28137..29714
                     /gene="ybtE"
                     /locus_tag="ROH59_002530"
     CDS             28137..29714
                     /gene="ybtE"
                     /locus_tag="ROH59_002530"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salycil-AMP ligase
                     YbtE"
                     /protein_id="HDX4804998.1"
                     /translation="MNSSFESLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSA
                     LDAQVDELAAGLSSLGLRSGEHVIVQLPNDNAFVTLLFALLRLGVIPVLAMPSQRALD
                     IDALIELAQPVAYVIHGENLAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGER
                     QAWPQPDVSATALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLP
                     VAHNFPLACPGILGTLACGGKVVLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQA
                     REWEDSDLSSLRVIQAGGARLDPTLAEQVIATFDCTLQQVFGMAEGLLCFTRLDDPHA
                     TILHSQGRPLSPLDEIRIVDQDENDVAPGETGQLLTRGPYTISGYYRAPAHNAQAFTA
                     QGFYRTGDNVRLDEVGNLHVEGRIKEQINRAGEKIAAAEVESALLRLAEVQDCAVVAA
                     PDTLLGERICAFIIAQQVPTDYQQLRQQLTRMGLSAWKIPDQIEFLDHWPLTAVGKID
                     KKRLTALAVDRYRHSAQ"
     gene            29845..31866
                     /gene="fyuA"
                     /locus_tag="ROH59_002531"
     CDS             29845..31866
                     /gene="fyuA"
                     /locus_tag="ROH59_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore yersiniabactin receptor FyuA"
                     /protein_id="HDX4804999.1"
                     /translation="MKMTRLYPLALGGLLLPAIANAQTSQQDESTLVVTASKQSSRSA
                     SANNVSSTVVSAPELSDAGVTASDKLPRVLPGLNIENSGNMLFSTISLRGVSSAQDFY
                     NPAVTLYVDGVPQLSTNTIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDST
                     PRGYIEGGVSSRDSYRSKFNLSGPIQDGLLYGSVTLLRQVDDGDMINPATGSDDLGGT
                     RASIGNVKLRLAPDDQPWEMGFAASRECTRATQDAYVGWNDIKGRKLSISDGSPDPYM
                     RRCTDSQTLSGKYTTDDWVFNLISAWQQQHYSRTFPSGSLIVNMPQRWNQDVQELRAA
                     TLGDARTVDMVFGLYRQNTREKLNSAYDMPTMPYLSSTGYTTAETLAAYSDLTWHLTD
                     RFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQLSAGYMLTDDWRVYTR
                     VAQGYKPSGYNIVPTAGLDAKPFVAEKSINYELGTRYETADVTLQAATFYTHTKDMQL
                     YSGPVGMQTLSNAGKADATGVELEAKWRFAPGWSWDINGNVIRSEFTNDSELYHGNRV
                     PFVPRYGAGSSVNGVIDTRYGALMPRLAVNLVGPHYFDGDNQLRQGTYATLDSSLGWQ
                     ATERMNISVYVDNLFDRRYRTYGYMNGSSAVAQVNMGRTVGINTRIDFF"
     gene            32516..33265
                     /locus_tag="ROH59_002532"
     CDS             32516..33265
                     /locus_tag="ROH59_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter beta domain-containing
                     protein"
                     /protein_id="HDX4805000.1"
                     /translation="MSKKYQPLLITHYMSTWVTITEAVEITTKAIKQKITPSDIYRHA
                     LSGNILLSIYFQSPVILKKIQTFNGKIKFRQFVGDLLDKLCMLDSDGFIYGQNLRLCT
                     EARYICPVQQIIDTPLLRKLNQFRTFVRNVRPGDELDVQAQVSEKNLTPPPGNSSGNL
                     EQQIASTSQLIGSLLAEDMNSEQAANIARGWASSQASGVMTDWLSRFGTARITLGVDE
                     DFSLKNSRDGNPRKWRFDATNSELCAERHEC"
     gene            33192..35314
                     /locus_tag="ROH59_002533"
                     /pseudo
     CDS             33192..35314
                     /locus_tag="ROH59_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416485.4"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
     gene            complement(35484..36536)
                     /locus_tag="ROH59_002534"
     CDS             complement(35484..36536)
                     /locus_tag="ROH59_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HDX4805001.1"
                     /translation="MFLVSLLRRIAFSYYDYKTYNFNIEKTDFVVIHIPDQIGDAMAI
                     FPVIRALELHKIKHLLIVTSTINLEVFNALKLEQTKLTLVTMTMQDHATLKEIKDLAK
                     NITLQYGTPDLCIEAMRKKNLKTMIFISQLKAKTNFQVVGLTMKCYSPLCKNASRMDQ
                     NLRAPVPMTWAFMMREAGFPAVRSIYELPLSDDVLDEVREEMRSLGSYIALNLEGSSQ
                     ERTFSLSIAENLIAKIQSETDIPIVIVYGPKGEDKARALVDCYNNVYRLSLSPSIKRS
                     AAIIKDAYIAITPDTSILHMASAYNTPVVAIYADYKTRWPAMADVSESVVVGQKIDNI
                     SLDEFAKALKSVLARI"
     gene            36851..38167
                     /gene="shiA"
                     /locus_tag="ROH59_002535"
     CDS             36851..38167
                     /gene="shiA"
                     /locus_tag="ROH59_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HDX4805002.1"
                     /translation="MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     MMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHNQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGALIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDNQRS"
     gene            38269..39723
                     /gene="amn"
                     /locus_tag="ROH59_002536"
     CDS             38269..39723
                     /gene="amn"
                     /locus_tag="ROH59_002536"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HDX4805003.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGKYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
     gene            40066..>40770
                     /locus_tag="ROH59_002537"
     CDS             40066..>40770
                     /locus_tag="ROH59_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX4805004.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQIPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGTDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQKVYHNV"
BASE COUNT         9357 a        11611 c        10789 g         9013 t
ORIGIN      
        1 acgcaacttc agttcccgcc agcaactttg cggcagtttc ataggatcaa tgtctaaaag
       61 aataatggtg accgataaga aaacgactga ataactgtag attttcgctc gaaaccttcc
      121 tgtcagaccc atagcgaatc aagtgctgaa tgtcacagta tcgaacagaa aacagtgacg
      181 atctaaccct tcaagaatat cctacgattg ttctgtttag gaaaagcaag gcgggaagtc
      241 gggagataag tcattgataa agtggcggag agagggggat ttgaaccccc ggtagagttg
      301 cccctactcc ggttttcgag accggtccgt tcagccgctc cggcatctct ccgttcagat
      361 ggttgccatg atgccaggaa atttggcatt ttaacagtcc ctgtccgtgc aattttgttc
      421 aagtgacgag tttgcgagca aaacgatgat taagtggccc tggaaagtac aagaatcagc
      481 acatcaaact gcccttccct ggcaggaagc actatcgatc ccccttttaa cgtgtctgac
      541 agaacaggaa caaagcaaat tggtcgctct tgccgaacgt tttttacagc aaaaacggct
      601 tgttccttta cagggctttg agctgaattc attaagaagc tgccggatag cacttctatt
      661 ttgcctgccc gttctggagt taggactgga atggctggat ggttttcatg aaatcttaat
      721 ttatcctgcg ccatttgtgg tcgatgatga atgggaagac gatatcggtc tggtgcataa
      781 ccaacgtatt gttcagtcag gtcagagctg gcagcaaggg cctatcgttt tgaactggtt
      841 ggatatacaa gattcttttg atgcttctgg ttttaacctg attattcatg aagtcgctca
      901 taagctggac acccgtaacg gcgatcgcgc cagcggagtt ccctttattt cgttgcgtga
      961 ggttgctggc tgggaacacg atcttcatgc tgcaatgaac aacattcagg aagaaatcga
     1021 attagttggt gagaatgcgg cgagcattga tgcttatgct gccagtgatc ctgctgaatg
     1081 ttttgccgta ctttctgaat atttctttag cgccccagaa ctttttgctc ctcgtttccc
     1141 ttcattgtgg caacgtttct gtcaatttta tcaacaagat cctttgcaga gactgcatca
     1201 cgctaatgat acagactcgt tttcggcgac gaatgttcat taattaacaa ctttgcagat
     1261 taattaacca attgaaatgg cttatgaaat ttagtgttga cagacaaggt accgctaagt
     1321 aatatgcgcc ccgttctcac gattcctctg tagttcagtc ggtagaacgg cggactgtta
     1381 atccgtatgt cactggttcg agtccagtca gaggagccaa ttttctgttt tcatgcatcc
     1441 ttgcgaatct ttatctgatg ttgattcaac aggttagtgt gaaaactctt ctcagtgcat
     1501 tttgatttta ccctacgcat cgggaaaaat tggtggtcaa atctggggtc aggttagttc
     1561 gataatggag tgacccccat atgtccctta ccagcgcaaa aatccgcacc ctcaagcctt
     1621 ctgataaacc ctttaaagtc tccgattctc acggtctgta tctgcgggtc aagccgggtg
     1681 gctcccgcca ctggtatctc aaataccgta ttagcggtaa agaatcccgc attgcgctgg
     1741 gtacctatcc agccatctcc ctgtctgatg cgcgacagca acgtgaaggt atccgtaaaa
     1801 tgctggcgct gaatatcaac ccggtacagc agcgggctgc tgtacgtggc tcacgaacac
     1861 cggagaaagt ttttaaaaac gtggcgctgg cgtggcataa aagtaacagg aaatggtcgc
     1921 agaacaccgc cgaccgtctg cttgccagcc tgaacaatca catctttccg gtcatcggga
     1981 acctacctgt atcagaactt aaaccccgtc atttcattga cctgctgaaa gggatcgagg
     2041 aaaaaggtct gctggaggtt gcgtcccgca cacggcagca cctgagtaac ataatgcgcc
     2101 atgcggtcca tcaggagtta atcgatacga accctgcagc aaaccttggc ggcgtgacca
     2161 cacctcctgt cagacggcac tatcctgccc tgccgctgga gcggctgcct gaactgcttg
     2221 aacgtattgg ggcatatcat cagggccgtg aactgacccg gcatgccgtt ctgctgatgc
     2281 tgcatgtgtt cattcgctcc agtgaactgc gtttcgcccg ctggtcagag attgatttca
     2341 caaaccgagt ctggacgata cccgcgacgc gagaacccat tattggcgtg cgttattccg
     2401 gccgcggggc aaaaatgcga atgccgcata tcgtccccct ctcagaacag tccatcgcca
     2461 ttctgaaaca gattaaggat atcaccggta ataatgaact gatcttcccc ggcgaccata
     2521 acccgtataa gccaatgtgt gaaaacacgg tcaataaggc actgcgggtg atgggttacg
     2581 acacgaaaaa ggatatctgc ggtcacggct tccgggcaat ggcatgcagt gcgctgatgg
     2641 aatcgggttt atgggcaaag gacgcagtag aacgccagat gagtcatcag gagcgcaata
     2701 ccgtgcgcat ggcttatatt cataaggcag agcacctgga agcccgcaaa gcgatgatgc
     2761 agtggtggtc ggattatctg gaagcatgcc gagaatctta tgcaccgcct tatacaattg
     2821 gtaaaaataa gtttatccca tagtatacta acgaatccca cactctggca aattaccacc
     2881 acctccacaa gaggtggttc tatatagact tttatcaact tcatgacgaa aaacacctat
     2941 tttatcccaa aagaagacaa tagagtcaca gaggaatcaa agagcgactc aattgtcttt
     3001 ggacagtctg gttgtgaggt tagaaaacag ttactcctac accattaaat agggcgcaat
     3061 gctcgctaat ttctcccggg tttctgtcag ttcgcgttcc ggcgtagatt gcgcgatgat
     3121 tcccgccccc gcctgtatcc agcagcgctg gctatcctga aatacggaac gcagaactag
     3181 cgccgcatca aagcgcgtat cgtccagcag caggattgcg ccggaataaa gctctcgcgg
     3241 cgtcttctca atttgcataa tcgcgttcag agcagcattt ttagggatac ctgaggcggt
     3301 aatcgacgga aacagcacgg taaacgcatc ccaggcatcc ttgttttccg caagctgacc
     3361 gctcacgcca gaccccagat gctgaacgct gccgcgctgg cgaaccgaca ttaaatcttc
     3421 aaccaccacg ctgcccggct ggcaaacggc ctccagttca gcaatagctt ctttgacaga
     3481 aaggatatgc tcaagcacct ctttactgtc gtgcagcagt tctgcctctt tcgccttatt
     3541 atgctccggg tttcccatgc gatcgcgggt gcccgcaagc ggttcagtga ccactttatt
     3601 gcccgtcact gacatcacca gttctgggct aaagcccagc gcttcgcgtc cttcctgacg
     3661 gaacataaac gagcgcacag gcgtgtttgc ctgccgcccg tataacagcg tggcgggcat
     3721 atcaatccgc gatggcaggg gaatggcgcg cgagacaatc actttgacat actcgccacg
     3781 gcggatctcc gcaacggcgc gcgcaacctg ttgtttatat gcctcaccat tgagggcggt
     3841 atccaccgcc agtggtgcgt tctgcgtcgt tgtaccggcc tcttttaccc actcgcacaa
     3901 acgtcggcac ccgtcggcgg agtccgcata aacggtgaca tttccctttt caaaaataag
     3961 ttcttcacgg ggaacggtta acgtcagcag cggccactcc ccggcgttaa aggcaatccc
     4021 ccgcgcatgc gccgcaaagt tgaacccaac ctgtccatat acccgacgtc ctttcacctg
     4081 aggatgcgcc ataaaacgac gcgcgcagtc ggcaatggaa tccaccgccc atttttgctc
     4141 cccggcatca tcaataaatg tcgcctgcgt tccgtcggca ttaatgtgca gccgtgcctg
     4201 gcaccctttg cctaaatacc aacagggttg acgctcatag acataacact cttcttctgc
     4261 gaactggcgt aaaacgccag aaatcgtcgg tagccattgt tcctctggta acgccagatg
     4321 tagaaattca ctgattttca tcccttacct ctctgtgtta ttcgcggatc aatcaattgc
     4381 gcttgtcatc agttctcttg ccgaatgcag ccggatataa gcaacccacg ccgccagcaa
     4441 cgtgaatgcc ccggcaaaca ggaagcaggc cgcatagcca aaatgttgag caacaacgcc
     4501 accgataacg cctgccagaa tggcgattgc cgcatcagta cattgaaaga gggtgaagtc
     4561 gacaccggcc tgcaaaggcg atgaaagcga catcagcgtg gcgtaaagac agaccagcgc
     4621 gcaggccagc gaaatggact ggacaatgac cagacactgg agaatctgca gcagcagatg
     4681 acccggcgcc atcatgagcg tcatcaccac cgccagcagc gcgatcccct ggacgccata
     4741 agccgtcaac agcgctctgc cgggtgaggt gtatttcatc agcaatccgc cggccagcgt
     4801 tcctgctatg cccgctgcaa tattgccgcc gctgaacagc gcgcccaatg cggacatgct
     4861 caacccatga tccaacaaca gcggtgccag aagaggcagc acaaaccgca tgcctgaatt
     4921 cagcatcaat accagcagta agcccaggcg cgcctgcttc ctccttagcg cataacctaa
     4981 cgccggaaca tgcgggatag tcgctgttcg cgtcggctcc gtaatgcgcc acagcgggag
     5041 tgacagcgcc ataatcagca ccgccatcat cagcatggcg acaggccagc cggatgccgc
     5101 cgacagcatc atgaacaccc cgccgccgca catcattccc agatagctgc cgccgacctg
     5161 cacgctgttt ccccagccgt aacccgtgcg ggtcagttga tcgacacaaa agccgtcgct
     5221 ggcgatatca atggtggagg cgaccgtgcc tgccaccata aacagaacaa ataacgcgac
     5281 gatttgcgta tcggggaatc ccccttctcg cccaaaccag ccaatcgctg cggcaatagt
     5341 caggatcgcc gctagcgcga cctgaccacg caggattaac atgcgggaac ggcgttcctg
     5401 gctaccgggc ggaagccgcc agcgctcgat ccacggcgcc caaataaact tcagcgccca
     5461 gggcagcata aacagggttg tcgcaccggc aagcgccagc gaaccgccag cagcgcgcac
     5521 cagcgcgggt aaggactgca tagacagcgc cgataccaga ctctgcgtca catagacgcc
     5581 ggcaatagca aaaatcaccc gcccggtcgt caacgtcagc ggtttcacat tcgactgaac
     5641 atcactcatg cccccactct ccagacgcgg aaaccccgtc gtcgcgccac acgcgcgcgg
     5701 ccatttgcgc ctgccacagc gcctgataac gtccatgatg tgagagcaat tgcgcatgag
     5761 taccctgctc aaccacctgt ccctcttcca tcaccagaat gtttccggcc ccggcgatgg
     5821 tggataaacg gtgagcgatg ataatcaccg tccggttgta aaccaggtta tcgatcgctt
     5881 tttgcaccgc cagctcgctt tcaatatcca gcgcggcagt cggttcatcg agaataacga
     5941 ccggcgcgtt tttcaataac gctctggcaa tggaaatccg ctggcgctcg ccgcccgata
     6001 gctggccgcc catctctccc attggcgtca gccagccttg cggaagacgg gaaataaact
     6061 caaggcactg cgccgcgcgg gcggcctctt ctacctcctg ccgcgtcgcc tgtgggcgcg
     6121 cgatacggat attcgccagc agcgtgtcat caaacagcca gacatcctgg aaaacaacag
     6181 aaatcaggct attgagctgt tccggcgtca ggcggcgaat atcgacgccg ccaatagaaa
     6241 tctgcccttg ctgcggatcg gcatagcgca ttaacagttt ggtgacggta gttttgcctg
     6301 cgccggaggc acccaccagc gcgctcatac tggctgccgg gaacgtcaaa gaaacatgat
     6361 taagcgcgtg gccgtcacct tcttcgtagc gatagctgac gttgtcaaag cggatatcgt
     6421 aacgttccgg catctcgctt tgctctgcga cgggaagcgg tgctatcgcc ataaactgct
     6481 caatcctttg cagggcgctg gcgatcagtt ccacaaccga ggtgtagctg ataaacatcg
     6541 ccatcggttc tgcgaagcgc ataatcatcg cgacggcggc aatcaaaaag gcgaggttca
     6601 gagtgcccgt cactacccag acgatcccgg ataacaccac cacctgtagg cccaactcca
     6661 cgacgctggc gatcagcatc gtcgcgccag cgccctgacg gtgagtgcgg gtctgtaagt
     6721 tttccagcgc attgaaatgc gccagcagcg cccggctttt atcggcatcg ctgccgcagg
     6781 tgcgcaatac catcatcccc tgagcaaatt caacgatatc gccgctcaga cgctggtgcg
     6841 cttcccccag cgtctgcatt tgtcgccgca tcgccgggcg gcgccagtaa taaaacggca
     6901 ccagcagagg gaagatcagc aacatcacca gccccagccg ccagtctatc cacaatgtcg
     6961 ccagcgacgc cgtcagcggc gtgacaatgg tgagcagcaa aatattggct atcgcaataa
     7021 cataattgag gttttcatcc acgctgccca gcagcaaggc gttcatttca cccgccctgc
     7081 cgcgctggag cttctccagc ggcacgcggc gtaactgctc gccaagtcgc aggcgcaact
     7141 catgggtagc ctgcgccaga tgaccacggt attcaaagcc caggccatac cagcgtagca
     7201 ccagcgtcac aattgcggcg acgctgaagg ccatagccca gttaagaagt tgcggcgcgt
     7261 ctccccgtaa cagcgcatca atgatcggat aaagacaggc aaaggcgatc ccctgcatga
     7321 atgccgccag caacagcgcc agcatactgc gtcgcagcat cctggcctga ctgccaacgc
     7381 tggagataag ctggcgccag atgacgcgcc aggccaggtt atccgcagga ttattgtctt
     7441 tcattttcca tcacctcttc ctgtgttcca cccggcaccc aatgctgcgc ctgctgatag
     7501 tgttgccaga gccgttgata caggccgccc tgcgccaaca gttgcgtatg gttccccatt
     7561 tccctgagct gtccgtcgga aaacagcaat atcacatcgg cctgagtcac cattgagaga
     7621 cgatgcgcga ccatgatgac cgtccggcca cgcatggccg ccgcgagcgc cttgataagc
     7681 gccgcttcgt tttccgggtc agcaaacgcc gtcgcctcat cgagcaccag gatggggcga
     7741 tcctgcaaaa gcgcccgggc gatagtaatg cgctgccgct ggccgccgga gagaaatacc
     7801 ccacgttccc cgactcgagt gttgtaacct tctggcagag cgctaataaa atcatgggcc
     7861 tgcgccactc tggccgccgc tataaccgcc tccagcggcg tatccggcgc gcccagacga
     7921 atgttattgg ctatcgtgtc ggcaaaaagg aagttgtcct gaaacacaaa cgagagttgc
     7981 ttcatcaggg tgtccgtctg catatcacgc agatccacgc cgccaatacg gatatggcct
     8041 ttgtccgggt cggcgtaacg cagcagcaag cgcaccacgg tgctttttcc ggcgccgctt
     8101 ggcccgacca gcgccacaat ttgcccggca ggcacatgaa agctcacctc ctgcaacgcg
     8161 gcgccagtac gcgcttgcgg ataatgaaag ctcacctgct caaaggtaat gctcgcctct
     8221 tgcggctgct ggtcagactg cggcagcgat aactccggca tcgcgagaac ctgataaata
     8281 cgctgaatgc ttaaacgcgt ttgcgcgacc aggttattga gcatcatcat tggcattacg
     8341 gcttcggcca ttccgctgcc cagcagtaaa acggccaccc acgcgataaa atcgaaactg
     8401 ccatagtgca acaggccgta tcccgaccag atcaggacaa acagggtcgg gagaggattc
     8461 agaatcgaga aggaaaaacg cgctgaaaaa ccggctttgc gataccaggt tttgagcaca
     8521 tcgacccact cttcaagggc gcgttgatag cgcaaaaaac tggtgctgcc gctatcaaac
     8581 gttctcacca cgggcatggc ctgcacgaac tcaataaccg ccgcgctaac ctgctcgcgc
     8641 gccttatgat aacgctgagc catatcttcc gaacgctggc gggcgagcac gagaacaacc
     8701 gatccaaacg ccagtacccc cagcgtcgcg attgccagcc gccagtccag ccagaacaag
     8761 ataacgattg tcgccagcgg catgatgatc gcgcgggcat agagcggcgt gctgtcggcc
     8821 acaaaaatat gtaacgactt cacgtcatcc agcatcactt tcgccactga cccgctgccc
     8881 atttgctgta acacgccagg cggaagctgc aatgctttac gggctaacct gctgcgcaga
     8941 atgttctcca gatgaaaagc cgcgtaatga gaggtgttga acgcctgtaa gcgcagaaca
     9001 aaagttaaga ccacgcagcc gatcacgccg cccagcggcc aggccggaat agcgtcaggc
     9061 gtcgcgcgaa tgtcacgcag gctccacgcc agaaaaagga gcgcccccag gctggttaat
     9121 gccgccagcc ccgccagcgc catagctaaa ataaccttcc tgcgaaccgg tgtaatcacc
     9181 tgccaaagag gaaatcggga cagcgattca gtattggatg attgagatga catgggagta
     9241 actgaatttc ctgatgaatt tttacggacg ccaaaaacga caattcaggg tggcgttctg
     9301 agaattaatg tgaataataa ccattatcaa taactcatct accccattcg gttctattta
     9361 tacccgcatt ggtctaagcc acagggagat aaccaggtca tgacggagtc accgcaaacg
     9421 caatctgaaa tctctattca ccagttggtg gtcgggaaac ctgcaaacga tggcaatatt
     9481 cctgctcagt gtgaactgct gcgctgttcg ttgcaggaag gtatggatat tttgctctgg
     9541 aggggccatt ttgcgcggcc tgagacgttg cagctacacg acgatctggg caggattaac
     9601 ttctcgtgca tcctggaagg cacatcgcgc tttgcgattc agggactccg gcgtcacacc
     9661 gactgggagc ttgcgcgcaa tcgccattac attacccata cgccagactg tcgcggcagc
     9721 gcctcctatt gtggccgatt cgagagcatt accctctcct tcagccctga aaccctcgcg
     9781 ctgtgggtgc cggatattag cgcggtcatt aagaataaga tcgactccca ctgctgttgc
     9841 cagcagcacc gttgtaatgc tgaaacccac ttaacggctc aggccttgcg tcacgcgctg
     9901 atgcgcatgc acagcggctt cagtcatgaa caaaagccgt cgacgctatg gttgcagggg
     9961 caaagtctgg tcatgctcag tctggtgctg gatgaacatc gcgaagacgc cagttgcctc
    10021 tcctgccact tcaccccgat ggaacgccag aaactgctgc gggcgaagga tctgctgctg
    10081 gctgatctga cgcaagcgcc gggcgtcgcg gagctggcca gagagtccgg tctgagcgtt
    10141 ctcaaaatta agcgaggctt ccgcgttctg ttcaacaaca gcgtctatgg cctgtttcag
    10201 gctgaacgaa tgcaggaagc cagaagacgc ctggccaacg gcaatacctc cgtcatgacg
    10261 gtggcggccg atctgggcta tgccaacgcc agccatttct ctgccgcctt ccagaaacag
    10321 tttggcgtaa ctccttcgac ctttaaacgc gggatgtaac cggggtcgcg cccccctaaa
    10381 ctcctccctg acagaggccc ggatacccca tcagggcctc tgttctttcc gcctgttacc
    10441 aacccgaaac gggcataaat aaacccgttt cgggtagcat ccaattgtta ataattatta
    10501 ttctcatatg agtaatgctt ttcggtaaga cgtgccatca ggaggaagaa tgatttctgg
    10561 cgcaccatct caggattcgc tgttaccgga caaccgccac gcggctgatt accaacaatt
    10621 acgcgagcgg ctcatacagg aactgaattt aacgccgcag cagttacatg aagagagcaa
    10681 cctgatccag gccggcctgg attccataag attgatgaga tggttacact ggtttcgtaa
    10741 aaatggctac cgccttaccc ttcgcgagct gtatgccgcc cccacgctgg cggcatggaa
    10801 ccagttaatg ctcagccggt cgccggagaa cgcggaagaa gaaacgccgc ccgacgaatc
    10861 atcctggccg aacatgaccg aaagtacccc cttcccattg acgccagtac agcacgccta
    10921 cctgacgggc cgcatgccgg ggcagacgct tggcggcgtg ggttgccacc tgtatcagga
    10981 gtttgaaggc cattgtctga cggcgtcgca gctggagcag gccatcacga ccttgctgca
    11041 acgccaccca atgctgcata tcgcctttcg ccccgacggg cagcaggtct ggctaccgca
    11101 accttactgg aacggcgtca ccgttcatga tttacgccat aacgacgctg aaagccgcca
    11161 ggcctatctg gacgcactgc gccagcgcct gagccaccgt cttttacgcg tggaaatcgg
    11221 cgaaacgttt gattttcagc tgacgctctt gccggacaat cgccaccgcc tccatgtcaa
    11281 tattgacctg ctgattatgg atgcctccag ctttacgctt ttcttcgatg agcttaacgc
    11341 cctgctggcc ggagaatcgc tgccggctat cgacacccgc tatgatttcc gctcgtattt
    11401 gctgcaccag cagaagatca atcaaccact gagagacgac gcgcgcgctt actggctggc
    11461 gaaagcatcg acgcttcccc ccgcgcccgt cttgccgctg gcctgcgaac ccgccacgct
    11521 acgtgaagtc cgtaataccc gacgccgcat gattgtcccg gcaacacgct ggcacgcctt
    11581 tagcaaccgg gccggcgagt atggcgtgac gccgacaatg gcactggcga cctgtttttc
    11641 tgccgtgctg gctcgctggg gcggcctgac gcgtctgctg cttaacatca ccttattcga
    11701 ccgccagccg ctgcacccgg cggttggcgc gatgcttgcc gacttcacca atattcttct
    11761 gctggatacc gcctgcgatg gcgataccgt cagcaacctg gcgcgtaaaa accagctcac
    11821 gtttacggag gactgggagc atcgccactg gtccggcgtc gaattactcc gtgaactcaa
    11881 acgccagcag cgctaccccc acggcgcccc ggtggtattt accagcaatc tggggcgttc
    11941 cctctacagc agccgcgcag aatcgccgtt gggcgagccg gaatggggca tctcgcaaac
    12001 gccgcaggtc tggatagatc atctggcgtt cgagcatcac ggcgaggtct ggctacaatg
    12061 ggacagcaac gacgcgctgt tccctccggc gttagtcgaa acattgttcg atacctactg
    12121 ccagttgatt aaccaactct gcgatgacga aagcgcctgg caaaagccgt tcgcagatat
    12181 gatgcccgcc agccagcgcg cgatacgcga acgggtcaac gccaccggcg cccccattcc
    12241 cgaaggcttg ctgcatgaag gcattttccg tatcgctctg caacagccgc aggcgctggc
    12301 ggtaacggac atgcgttatc agtggaatta tcatgagctg acagactatg cccgccgttg
    12361 cgcgggcagg ttaatcgagt gcggggttca gcccggcgat aatgtggcta tcacgatgtc
    12421 gaaaggtgca ggacaacttg ttgcggttct ggccgtcctg ctggctgggg cggtttacgt
    12481 tccggtttcg ctggatcagc ctgccgcacg gcgcgagaaa atctacgctg acgccagcgt
    12541 ccggctggtg ctcatttgtc agcacgacgc cagcgccggg tcagacgata ttcccgtcct
    12601 tgcctggcag caggccattg aggcggagcc gatcgccaac ccggtagtac gcgcccccac
    12661 gcaaccggcc tacattatct acacctccgg ctctaccggt acgccgaaag gggtagtcat
    12721 ttctcaccgg ggagcgctta acacctgttg cgatatcaat acccgctatc aggttggccc
    12781 gcatgacagg gtgctggccc tctccgccct acattttgat ttatcggttt acgacatttt
    12841 tggcgtactg cgcgcgggcg gcgcgctggt gatggtgatg gaaaatcaac ggcgcgatcc
    12901 tcacgcatgg tgtgagctga tccagcgcca tcaggtcacg ctctggaaca gcgtcccggc
    12961 gctgttcgat atgctgctga cctggtgtga aggtttcgcc gacgccacgc cggaaaacct
    13021 gcgcgcagtg atgctttccg gcgactggat cgggcttgac ctccccgccc gttatcgggc
    13081 cttccggcca caaggacaat ttatcgcgat gggcggtgcc accgaggcgt ctatctggtc
    13141 taacgcctgc gaaattcacg acgtccccgc ccactggcgc tccatccctt acggttttcc
    13201 gctaaccaac caacgctacc gggtggtgga tgaacagggc cgggactgcc ctgactgggt
    13261 gccgggtgaa ttatggattg gcggcattgg ggtcgcggaa ggctatttca acgatcccct
    13321 gcgtagcgag cagcaatttt tgacgctccc ggacgagcgc tggtatcgca ccggcgatct
    13381 cggctgctac tggccagatg gcacaatcga gttcctcggt cgtcgcgaca agcaggtcaa
    13441 agtcggagga tatcgcatcg agctgggcga aatcgaaagc gcgctcagcc agctggcggg
    13501 ggtgaaacaa gcaaccgttc tggcgatcgg cgaaaaagaa aaaacgctgg cggcatacgt
    13561 tgttcctcag ggcgaggctt tttgcgttac cgatcatcgg aacccggcac tgccgcaggc
    13621 gtggcacacg cttgcgggaa cgttgccctg ttgcgccatc tcgccagaga tctccgcaga
    13681 acaggtagcc gatttccttc agcatcgcct gctaaaactg aagccgggtc acaccgctgg
    13741 cgccgatcct ctccccctga tgaactcact cgctatccag ccgcgctggc aggccgtggt
    13801 ggaacgctgg ttagcatttc tggtgacaca acggcgactg aagcccgctg ctgaaggtta
    13861 tcaggtctgc gctggtgaag aacgcgagga tgagcacccg cacttcagcg gacatgattt
    13921 aacgttatcg caaattcttc gcggtgcccg taacgaactg tcgttactga acgacgcgca
    13981 gtggtcgccg gaaagcctgg cctttaacca tccggccagc gccccgtata ttcaggaact
    14041 ggcgacaatt tgccaacagc ttgcacagcg cttacagcgc ccggtgcgcc tgcttgaggt
    14101 gggaacccgc actggccgcg ccgcagaatc gctgttagca cagctcaacg ccggacagat
    14161 tgagtatgtc gggcttgagc agagccagga gatgctgctg agcgcccggc agaggctcgc
    14221 cccctggcct ggcgcccgtc tgtccctctg gaatgcagac acgctggcgg cgcacgctca
    14281 ctcggcggac attatctggc ttaataacgc cctgcatcgt ctgctgccgg aagatcccgg
    14341 gctccttgcg acattacaac agcttgccgt tcccggcgcg ctgctctacg tgatggagtt
    14401 tcgccagtta acgccgtccg ccctactcag cacgctcctg ttaaccaatg ggcagccgga
    14461 ggccttgctg cataacagcg ccgactgggc ggcattattt agcgcggccg gcttcaactg
    14521 tcagcatggc gatgaggtcg cggggttaca acgcttcctc gtacaatgtc ctgacaggca
    14581 ggtgcgccgc gatccccgtc aacttcaggc cgccctcgcc gggcgtctgc cggggtggat
    14641 ggtgccgcaa cggatcgtct tcctcgacgc cttaccgctg acggctaacg ggaaaattga
    14701 ctaccaggcg ctgaagcgtc gtcatacccc tgaagcggaa aacccggccg aagcggattt
    14761 accccagggc gacattgaaa aacaggttgc cgccctctgg cagcaactct tatcaactgg
    14821 caatgtcacc agagaaaccg acttcttcca gcaaggcggc gatagcctgc tggcgacccg
    14881 tctgaccggg caacttcatc aggcaggtta tgaagcgcaa ttaagcgacc tgtttaatca
    14941 tccccggctg gcggattttg ccgccacgct gcggaaaacc gacgtcccgg tcgaacaacc
    15001 attcgtccac tcccctgaag atcgctacca gccctttgcg cttaccgacg tgcagcaggc
    15061 ttacctagtg gggcgtcagc cgggctttgc cctgggcggc gtcggctcac atttctttgt
    15121 tgaatttgaa attgccgatc tggatctcac ccggttggag acggtctgga accgattaat
    15181 cgcccgccac gatatgctac gcgccgtcgt gcgtgatgga cagcaacagg tgctcgaaca
    15241 gacgcctcgc tgggtaatac ccgcacacat cctccatacg cctgaagagg cgttgcaggt
    15301 gcgcgaaaaa ctggcccatc aggtactcaa ccccgaagtc tggccggtat tcgatctcca
    15361 ggtcggttac gttgacggga tgcccgcccg cctgtggctg tgtctggata acctgttact
    15421 tgacgggctg agcatgcaga ttctgttggc ggagctggag cacggctacc gctacccgca
    15481 acagctgctt ccgccgctgc ccgtcacctt cagggattat ctgcaacaac cctcgctaca
    15541 gtcgcccaat ccagattctc tggcatggtg gcaggcgcag cttgatgata ttcctccggc
    15601 gcctgcgttg ccgctgcgct gcttgcctca ggaggttgaa acaccgcgct tcgcccgcct
    15661 gaacggcgca ctggacagca cgcgctggca tcggctgaaa aaacgggcgg ctgacgccca
    15721 tctcaccccg tcggccgtac tgttgtcggt gtggtcaacg gttctctctg catggagtgc
    15781 acagcctgag ttcacgctta accttacgct tttcgacagg cgaccgctgc acccgcaaat
    15841 caaccagatt ctgggcgatt tcacctcgct gatgctgctg agctggcatc ccggcgaaag
    15901 ctggctgcac agcgcgcagt cactacagca gcggctgagc cagaacctca accaccgcga
    15961 tgtgtcagcc atccgcgtga tgcgtcaact ggcgcaacgg caaaacgtgc cagccgttcc
    16021 gatgcccgtc gtctttacca gcgcgctggg ctttgagcag gataacttcc tcgcccggcg
    16081 taatctgctc aaaccggtct ggggcatctc ccagacgccg caggtctggc tcgatcacca
    16141 gatttatgaa tccgaaggcg aactgcgctt taactgggat tttgtcgccg cgctgtttcc
    16201 tgccgggcag gtggagcgcc agtttgaaca gtattgcgca ttgctaaacc gaatggccga
    16261 ggatgaaagc ggctggcaac tgccgctcgc cgcgctggtg cctcccgtta aacacgcagg
    16321 gcaatgcgca gagcgctcac cgcgcgtatg ccctgagcac tctcagccac acattgcggc
    16381 ggacgagagc accgtcagcc tgatttgcga cgccttccgc gaggtggttg gcgagtctgt
    16441 cacgcccgca gaaaacttct ttgaggcggg cgcaacgtcg ctgaatctgg tgcaactgca
    16501 cgttttgtta caacgtcacg aattttccac cctgacgttg cttgacctct tcacccaccc
    16561 ttctcctgct gccctggccg attatctggc cggcgtcgcc acggtggaga aaacaaaacg
    16621 acctcgccct gttcgccgtc gtcagcggcg gatatagcgc gaagcaaact gattttcccc
    16681 ggaacgccat cgcgaacgca tggcgttcca ttgactttgt gaatcttagg aaacgggacc
    16741 gattatggat aacttgcgct tctcttctgc gccgacagca gattccattg atgcatcgat
    16801 cgctcaacac tacccggact gcgaacctgt cgcggttatc ggctacgcct gccattttcc
    16861 tgaatcgccg gatggcgaaa cgttctggca aaatctgctg gaaggtcgtg aatgcagccg
    16921 acgctttacg cgcgaagagc ttctggccgt cggtctggat gccgccatca ttgacgatcc
    16981 tcattatgtc aatatcggta cggtgttaga caacgccgac tgcttcgacg ccaccctgtt
    17041 tggctattcg cgacaggaag cggagtcgat ggacccgcag cagcgcctgt ttttgcaggc
    17101 ggtctggcat gcgctggaac atgccggtta tgcccccggc gccgtccccc ataagaccgg
    17161 cgttttcgcc tcttcccgga tgagtaccta ccccggtcgc gaagcattga acgtgacaga
    17221 agtcgcgcag gtaaaaggtc tgcaatctct gatgggcaat gataaagact atattgccac
    17281 ccgcgccgcg tacaaactca acctgcacgg cccggcgtta tcggtacaga ccgcctgctc
    17341 cagctcgctg gttgccgtgc atctggcctg tgaaagcctg cgcgcaggcg aatccgatat
    17401 ggcggttgcc ggcggcgtgg cgctctcttt cccccagcag gcaggctacc gctaccagcc
    17461 cggaatgatt ttctctcctg atggtcactg tcgtcccttt gacgcctcgg ctgagggcac
    17521 ctgggccggt aacggtctcg gctgcgtggt gctgcgtcgc ctgagagacg cgctgctgtc
    17581 aggcgatccg attatctcgg tgatcctctc cagcgcggtc aacaacgacg gcaacagaaa
    17641 ggtcggctat accgcccctt ccgtcgcagg gcaacaagca gtcatcgaag aggcgttaat
    17701 gctggcggcc atcgacgaca ggcaggtagg ttacattgaa acccacggca ccggcacacc
    17761 gctgggcgac gcgattgaaa ttgaagcgtt acgcaacgtc tatgcgcctc gcccgcagga
    17821 tcagcgctgt gcgctcggtt ccgtgaaaag taacatgggc catctggata ccgcggcggg
    17881 cattgccgga ctgctgaaaa ccgttctggc agtcagtcgc gggcaaattc ctcccttact
    17941 gaattttcac acccccaacc cggcgctgaa acttgaagag agccccttta ccataccggt
    18001 gtcggcacag gcatggcagg acgaaatgcg ctatgcgggc gtctcctcct ttggtattgg
    18061 cggcaccaac tgccatatga tcgtcgcctc gctgcccgac gcgctcaacg cgcgcctccc
    18121 caatacggat agcggcagaa aaagtaccgc gctgctgctc agcgccgcca gcgacagcgc
    18181 gttgcggcgg ctggcgacgg attatgccgg ggcgctgaga gagaatgcgg atgccagctc
    18241 tctggccttc acagccctgc acgcgcgccg tctcgatctc cccttccgcc tggcggcgcc
    18301 attaaaccgt gaaaccgccg aggcgctcag cgcctgggcc ggtgagaaat cgggggcgct
    18361 ggtttacagc ggccacggcg ccagcggcaa gcaggtgtgg ctgtttaccg gccagggctc
    18421 gcactggcgc actatgggtc aaacgatgta ccagcactca acggcgtttg ccgacacgct
    18481 ggatcgctgt ttttccgcct gtagcgaaat gctcacgccg tcactgcgcg aagcgatgtt
    18541 taaccccgat tcggcgcagc tggacaatat ggcctgggcg cagccggcga ttgtcgcgtt
    18601 tgaaatcgcg atggcggcgc actggcgtgc tgaaggactg aagccagact tcgccattgg
    18661 gcattccgtc ggtgaatttg ccgctgccgt tgtctgcgga cactatacga ttgaacaggt
    18721 catgccactg gtttgtcggc gcggcgcgct aatgcagcag tgcgcaagcg gcgcgatggt
    18781 ggcggtattt gcagacgaag acacgctgat gccgctggct cgccagtttg agctggatct
    18841 cgccgccaac aacggtacgc aacatacggt attttccggg ccggaagccc gtctcgcggt
    18901 attttgcgcc acgctctcgc agcatgacat taactatcgt cgcctgagcg taaccggtgc
    18961 ggcgcactcc gctttactgg agccgatact cgatcggttc caggacgcct gcgcgggact
    19021 gcacgcggag ccggggcaaa taccgattat ttccacgctc accgccgacg tcattgatga
    19081 gtcaacgctc aaccaggcgg attactggcg ccgacacatg cgccagccgg tgcgttttat
    19141 ccagagtatt caggtggcgc atcagctcgg cgcccgcgtt tttctggaga tggggcccga
    19201 tgcccagttg gttgcttgcg ggcagcgcga ataccgcgat aacgcatact ggatagccag
    19261 cgcccggcgt aacaaagagg cgagcgatgt cctcaatcag gccctgctcc agctttacgc
    19321 tgccggcgtc gccctaccgt gggccgacct gctggcgggc gatggacaac gtatcgctgc
    19381 gccatgttat ccgtttgata ctgaacgtta ctggaaagag cgcgtctccc cggcctgcga
    19441 gcctgccgac gcagcgctgt ctgccgggct ggaggtggcg agtcgcgccg cgacagcgct
    19501 cgatctccct cgcctggatg cgcttaaaca gtgcgccacg cgactgcacg ccatctacgt
    19561 cgatcaactg gtacaacgct gtaccggcga tgccattgag aacggcgtgg acgccatgac
    19621 catcatgcgc cgtggacgtc tgctgccccg ctaccagcag ctactccagc gcctgctgaa
    19681 taactgcgtg gtcgacggcg attaccgctg caccgacggg cgatacgtcc gcgcccgccc
    19741 cattgaacat caacagcggg aatcactgct gacggaactt gccggttatt gtgaaggttt
    19801 tcaggctatt cccgacacca tcgcccgtgc cggcgatcgg ttatatgaaa tgatgagcgg
    19861 cgcggaagaa ccggtggcga ttatcttccc gcaaagcgcc tccgacggcg tggaagtgct
    19921 gtatcaggaa ttcagctttg gccgctattt caaccaaatc gccgccgggg tattacgcgg
    19981 cattgtccag acgcgtcagc cccgccagcc gttgcgtatt cttgaagttg gcggcggaac
    20041 cggcggcacc accgcgtggc tgctgccgga actcaacggc gttccggcac tggagtacca
    20101 tttcaccgat atctcggcgc tgttcacccg tcgcgcccag cagaaattcg ccgactatga
    20161 ttttgtgaag tatagcgagc tggatctcga aaaagaggcg cagtctcagg gtttccaggc
    20221 acagtcttac gatcttatcg tggcagcgaa cgtgattcac gccacccgcc atattggccg
    20281 cacgctcgat aatctgcgcc ccctgctcaa gccgggcggg cgcctgctga tgctcgaaat
    20341 cacccagcca atgcgtctgt ttgacttcgt tttcggcccg ctggttcttc cgctacagga
    20401 tctcgacgcc cgcgaaggtg agttattcct caccaccgct cagtggcaac aacagtgccg
    20461 ccacgccgga ttcagcaaag tggcgtggct accgcaggat ggcagcccga ccgccgggat
    20521 gagcgaacat atcattctcg ccacgctgcc cggtcaggcg gttagcgccg taacattcac
    20581 cgcgccatca gaacccgtgt tggggcaggc gctgacggat aacggtgatt atctcgccga
    20641 ctggtctgat tgcgcaggtc agcccgaacg gtttaacgcc cgctggcagg aggcatggcg
    20701 tctgctttca cagcgtcatg gcgacgctct gcctgtggaa ccgccccccg tcgccgcccc
    20761 ggagtggctg gggaaggttc gcttaagctg gcaaaacgaa gccttttccc gcggtcagat
    20821 gcgcgttgaa gcccgtcatc ctgctggcga gtggctgccg ctatcgcccg ccgcgcctct
    20881 tcctgcgccg caaacgcatt atcaatggcg ctggacgccc ctcaacgtcg ccagcattga
    20941 ccatccgctt acctttagct tcagcgccgg tacgcttgcg cgcagcgacg agctggcgca
    21001 atacggcatc attcacgatc cgcacgcctc ttcacgactg atgattgttg aggagagcga
    21061 ggatacgctg gccttagcgg agaaagtgat agcagcgctc accgccagcg cagccggatt
    21121 gattgtggtt actcgccgcg cgtggcgagt cgaggaaaat gaagcactct ctgcatccca
    21181 tcacgcgcta tgggccttgc ttcgcgtcgc ggccaacgaa cagccggaac ggttgcttgc
    21241 cgccatcgat ctcgccgaaa acaccccgtg ggaaacgctg catcaagggt tgagcgcagt
    21301 ctcactatca cagcgctggc tcgccgcacg gggtgacacc ctttggctcc cttcactgac
    21361 gcccaatacg ggatgcgccg ctgaattacc ggcaaacgtg tttaccggcg atagccgctg
    21421 gcatctggtg accggagcgt ttggcggatt aggccgcctt gccgtgaact ggctcagaga
    21481 aaaaggggcg cgacgcatcg ccctgctggc accgcgcgtg gatgagtcat ggctacgcga
    21541 cgtggagggc gggcagacgc gcgtctgccg ttgtgatgtg ggcgatgccg ggcaactggc
    21601 cacggttctt gacgatctgg cggccaacgg cggcattgcc ggagcgattc atgccgctgg
    21661 cgtattggct gacgcgccct tgcaggagct tgatgaccac cagctggctg ccgttttcgc
    21721 ggtaaaagcg caggcggcaa gccaactgtt gcaaaccctg cgcaaccacg acggacgcta
    21781 tcttattctc tactcttccg ctgccgccac cctcggcgcg ccgggtcaga gcgcccatgc
    21841 gctggcctgc ggctacctgg acgggctggc ccagcagttt tccacccttg atgcgccgaa
    21901 aacgctctct gtcgcctggg gcgcatgggg agaaagcggt cgggcggcca cgccggaaat
    21961 gctggcgacg ctcgccagcc gaggtatggg cgcgttaagc gatgccgaag gctgctggca
    22021 cctggaacag gcggtgatgc gcggcgcccc gtggcgactg gcgatgcgcg tttttaccga
    22081 caaaatgccc ccgttacaac aggctctgtt taacatcagc gccacagaaa aagccgcaac
    22141 gccggtcatt cctcctgctg atgacaacgc ctttaacggc agcctgagcg atgaaacagc
    22201 ggtgatggca tggctgaaaa agcggattgc ggttcagcta aggctgagcg atccggcgtc
    22261 actgcatcca aaccaggatc tgttgcaact cggcatggac tcgctgctct tccttgaact
    22321 cagtagcgat attcagcact acctgggtgt acgcatcaat gcggaacggg cgtggcagga
    22381 tctgtctcct catggactca cgcagcttat ctgttctaag ccagaggcga cgcctgccgc
    22441 ttcgcagccg gaagtattgc ggcacgacgc cgacgagcgt tatgcgccct tccctttgac
    22501 gcccattcag cacgcctact ggctggggcg aacccacctc attggctatg gcggcgtcgc
    22561 ctgtcacgtc ctgtttgagt gggataaacg ccacgatgag ttcgatctcg ccatactgga
    22621 gaaagcatgg aaccagctca tcgcacgcca cgatatgttg cgtatggtgg ttgatgccga
    22681 cgggcagcag cgaatcctgg cgacaacgcc ggagtatcac atcccgcgtg acgatctgcg
    22741 cgcgctttcc ccggaagaac agcgcatcgc actggaaaaa cggcggcatg aactgagcta
    22801 tcgcgttttg cctgccgacc agtggcctct ttttgagctg gtggtcagcg aaatcgacga
    22861 ttgccattac cgtctgcata tgaacctcga ccttttgcag tttgatgtgc agagttttaa
    22921 agtcatgatg gacgacctgg cgcaggtctg gcgcggtgaa acgctggcgc cgctcgctat
    22981 taccttccgt gattatgtga tggctgaaca ggcgcgccga cagacatcgg catggcacga
    23041 tgcctgggat tactggcagg aaaaactgcc gcaactgccc ttagcgccag agctgccggt
    23101 ggttgagacg cccccggaaa cgccacactt caccaccttc aaatcgacga tcggcaagac
    23161 agaatggcag gccgtgaaac agcgctggca gcagcaaggc gtcacaccgt ctgccgcgct
    23221 gctcacgctg tttgccgcca cccttgagcg ctggagccgt accacaacat ttacgctgaa
    23281 cctgacgttc ttcaatcgcc agccgatcca tccgcaaatc aaccagttga ttggtgattt
    23341 tacctccgtc acgctggttg attttaactt ctcagcgccg gtgacgttgc aagagcagat
    23401 gcaacagacc caacagcgcc tctggcaaaa catggcgcac agtgaaatga acggtgttga
    23461 ggtgatccgt gagctgggcc gcctgcgcgg atcacaacgt caaccgctga tgccggtagt
    23521 gtttaccagt atgctgggga tgacgctgga aggcatgact atcgatcagg cgatgagcca
    23581 tctgttcggc gaaccctgct atgtattcac gcaaacgccg caggtctggc tggatcatca
    23641 ggtcatggag agcgacggcg agttgatgtt tagctggtac tgcatggaca acgtgctgga
    23701 acccggcgct gccgaggcga tgtttaatga ctattgcgcc atcctgcaag ccgtcatcgc
    23761 cgcccctgaa agcctgaaga ctctcgccag cggcatcgcc aggcacattc cccgccgacg
    23821 ctggccgctg aacgcgcagg cggactacga cctgcgggat attgagcagg cgacgctcga
    23881 ataccccggc atccggcagg ccagagcgga aataaccgaa cagggcgcgt tgacgctgga
    23941 tatcgtgatg gccgacgatc cttcgccatc agcggcgatg cctgatgagc acgaacttac
    24001 ccaactggcg ctgccgttgc ctgagcaggc gcagcttgat gagctggagg cgacctggcg
    24061 ctggctggag gcgcgtgcgc tacaggggat cgcggctacg ctaaatcgtc acggcctgtt
    24121 taccacgccg gagatcgccc atcgctttag cgcagtagta caggcgctgt ccgcgcaagc
    24181 gtctcaccag cgtctgctgc gccagtggct acagtgtctg acggaaagag agtggttaat
    24241 ccgcgaaggt gaaagctggc gctgccgcat tccgctcagc gagattcctg agcctcagga
    24301 agcgtgcccg caaagccaat ggagccaggc gctggcgcag tatctggaaa cctgcatcgc
    24361 ccggcacgac gccctcttct ccgggcagtg ttctccgctg gaattgctgt tcaacgagca
    24421 gcatcgcgtt accgacgcgc tgtatcgcga caaccccgcc agcgcctgtc tgaatcgcta
    24481 taccgcgcag attgccgcct tgtgcagcgc agaacggatt ctggaggttg gcgccggaac
    24541 cgcagccact accgcgccgg tgctgaaggc cacgcggaac acgcggcagt cgtaccactt
    24601 cacggacgtc tccgcgcagt tcctcaatga cgccagagcc cgtttccatg atgaatcgca
    24661 ggtgtcttat gccttgttcg acatcaacca gccgctggat ttcaccgccc acccggaggc
    24721 gggttacgac ctgatcgttg ccgtcaatgt gctccacgac gccagccatg tcgtccagac
    24781 gttgcgcaga ttaaaactgt tgctgaaagc cggcggacgt ttgctgatcg ttgaagcgac
    24841 ggagcgaaac agcgtattcc agctggcgag cgtgggcttt attgagggat taagcggata
    24901 ccgcgatttc cgccgccggg atgagaaacc gatgctcacc cgctccgcat ggcaggaggt
    24961 tctcgttcag gccgggtttg caaacgagct ggcgtggccc gcgcaggaat cgtcgccgct
    25021 gcgccagcat ctgctggtag cgcgttcgcc tggcgtaaat cgcccggata aaaaagccgt
    25081 gagccgctat ttacagcagc gctttggcac cggtctgccc attttacaga tccggcaaag
    25141 agaagcgtta tttacgccgc tgcatgcccc gtctgatgcg ccgactgagc cagccaaacc
    25201 cacgccagtt gccgggggga atccggcact ggaaaaacag gtggctgaac tctggcaatc
    25261 gctgctgtct cgccccgtgg caaggcatca cgactttttc gaactgggcg gcgacagcct
    25321 gatggcgaca aggatggtcg cgcagctaaa ccggagaggg attgccaggg ctaaccttca
    25381 ggatctgttc agccattcga cgctgagcga cttctgcgcc catctacagg cggctacgtc
    25441 aggagaggac aacccgatac ccctttgcca gggcgacggt gaggaaaccc tgtttgtctt
    25501 ccacgcttca gacggcgata tcagcgcctg gctgccgctc gctagcgcgt tgaacaggcg
    25561 cgttttcggc ctgcaagcaa aatcgccgca gcgctttgcc acgctcgacc agatgatcga
    25621 tgagtatgtc gggtgcatcc gtcgtcagca gcctcacggc ccttatgtgc tggcgggttg
    25681 gtcgtatggc gcgtttcttg cggcgggcgc cgcacaacgc ctgtacgcca aaggcgagca
    25741 ggttcggatg gtgttaatcg atcccgtgtg ccgacaggat ttctgttgcg aaaaccgggc
    25801 ggccctgctg cgcctgttag ccgaaggaca aacgcctctg gcactgcccg aacatttcga
    25861 ccagcagacg cccgacagcc agcttgccga ctttatcagc ctcgctaaaa cggccggtat
    25921 ggtgtcgcaa aacctgacgc tgcaagcggc agaaacgtgg ctcgacaaca tcgcgcatct
    25981 gctgcgttta ctgactgagc atacgccggg cgaaagcgtt ccggtcccct gtctcatggt
    26041 gtatgccgcc gggagacccg cgcactggac gccagcagaa accgagtggc agggctggat
    26101 aaacaacgcc gacgacgctg tgattgaagc cagccactgg caaatcatga tggaagcccc
    26161 ccacgttcag gcttgtgcgc aacacattac gcgctggctt tgcgcaacct caacgcaacc
    26221 ggagaacacg ttatgatgcc gtccgcctcc ccaaaacaac gcgtactgat tgtgggcgcc
    26281 aaatttggcg aaatgtacct gaatgccttt atgcagcccc cggaggggct ggaactggtc
    26341 ggcctgctgg cgcagggaag cgcccgttca agagagctgg ctcatgcgtt tggcattccg
    26401 ctgtatacct cgccggaaca gataaccagg atgccggata tcgcctgtat tgtcgtgcgt
    26461 tcgaccgtcg ccggaggaac cggtacgcag cttgccagac actttctgac gcgcggcgta
    26521 cacgtcattc aggagcatcc cctccacccg gatgacatca gttccttaca aacgctggcg
    26581 caggaacagg gctgctgcta ttgggtaaac acgttttatc cgcatacgcg cgcgggacgc
    26641 acatggcttc gcgatgcgca gcagctgcgt cgctgtctgg ctaagacgcc gcaggtggtc
    26701 cacgccacca ccagccgaca gttgctctac tccactctgg atttgttgtt gctggctctg
    26761 ggcgttgatg ccgccgccgt ggagtgcgac gtggttggca gctttagcga ttttcactgt
    26821 ctgagactct tctggccgga gggagaagcc tgcctgctgc ttcagcgcta tctcgatcct
    26881 gacgatccag atatgcatag ccttatcatg caccgcctgc tgctgggctg gccggaaggt
    26941 catctttcgc tggaggcgag ctacggcccc gtcatctggt catccagcct gtttgtcgca
    27001 gaccatcagg agaacgccca cagcctctac cgcagaccgg agatcctgcg cgatctgccg
    27061 ggtctgacgc gcagcgcggc gcccctgagc tggcgcgact gctgcgaaac cgtcgggccg
    27121 gagggcgtca gctggttgct acaccagttg cgcagccatc tggcgggcga acatccacca
    27181 gcggcctgcc aaagcgtaca tcagatcgcg ttatcacgtt tatggcagca gattttacgt
    27241 aagaccggca atgcggagat cagacgcctg acgccgccgc accacgaccg gttagccggt
    27301 ttctacaacg atgatgataa ggaggcgctg tgacgcaatc tgcaatgtgc atcccgctgt
    27361 ggcccgcccg gaacggcaat actgcgcatc tggtcatgtg ccctttcgct ggcggcagca
    27421 gtagcgcgtt tcgccactgg caagctgagc aactggctga ttgcgcgctt tctctggtga
    27481 cctggccggg gcgcgatcgc cttcgccatc tggaaccgct cagaaacatt acacaactgg
    27541 cggcactgct ggcgaacgag ctggaagcat ccgtatcgcc tgacacgccg cttttactcg
    27601 ccgggcacag catgggggcg caggtggcgt ttgaaacctg ccgacttctg gagcaacggg
    27661 ggcttgcgcc acaaggactg attatttccg ggtgccatgc cccgcatctg cattctgaac
    27721 gccagctcag ccatcgcgat gatgccgact ttatcgctga gctgatagac attggcggat
    27781 gttctcctga actgcgggaa aaccaggaat taatgtcgct gtttcttcct cttctgcgcg
    27841 ctgattttta cgccaccgag agctatcact acgactcgcc cgacgtctgt ccgccgctgc
    27901 gcacgcctgc gctgttattg tgcggcagcc acgatcgcga agcctcctgg cagcaggtcg
    27961 atgcctggcg tcagtggctg agccacgtta caggcccggt ggtgattgac ggcgatcatt
    28021 tctatcccat tcaacaagcc cggtcctttt ttacgcagat tgtccgccat tttccccacg
    28081 cattttctgc aatgaccgcg tggcaaaaac agcccagtac ttcagaaagg tgacgcatga
    28141 attcttcctt tgaatctctg attgaacagt atcccttacc cattgccgaa cagttgcgcc
    28201 actgggcggc ccgttatgcc tcgcgaattg ccgtcgttga tgcaaagggg tcgttaacct
    28261 acagcgcgct tgatgcacaa gttgacgaac ttgccgcagg tctgtcatca ctgggtttgc
    28321 gttcggggga gcatgtaatt gtgcagcttc ccaacgacaa cgcgtttgtt accctgctgt
    28381 tcgccttgtt aagactgggc gttatccccg tgctggcgat gccctcgcaa cgggctctgg
    28441 atatcgacgc gctgattgag ctggcgcaac ccgtcgctta cgttattcac ggggaaaacc
    28501 tcgcagagct ggcccgacag atggcgcaca aacacgcctg cttgcgtcat gttctggtcg
    28561 ctggagagac cgtgagcgac gattttacgc cgctcttctc ccttcacggt gagcgacagg
    28621 catggccgca gcctgatgtt tccgccaccg cgttgttgtt gctctcaggc ggcacaaccg
    28681 gcacgcccaa actcatcccg cgccgacatg ccgactatag ctataacttc agcgcttctg
    28741 ctgaactgtg cggcatcagc caacagagcg tgtatctcgc cgtcctcccg gtggcgcata
    28801 actttccgct ggcctgcccc ggtattctgg gaacgcttgc ctgcggcgga aaagtggtgc
    28861 tgaccgacag cgccagctgt gatgaggtga tgcctttaat cgcgcaggaa agagtgactc
    28921 acgtcgccct ggttccggcg ctggcgcaat tatgggtgca ggccagggag tgggaagaca
    28981 gcgacctttc gtcgctgcgc gtcattcagg caggcggcgc ccggctcgac ccgacgcttg
    29041 ctgagcaggt tatcgccacc tttgactgta ccctgcaaca ggttttcggt atggcggaag
    29101 gcctgctctg ttttacccgg ctggacgatc cgcatgccac cattctccac agccaggggc
    29161 gcccgttgtc ccctctggat gaaatccgca tcgttgatca agacgagaac gacgtcgcgc
    29221 cgggcgaaac cgggcaattg ttaacgcgcg gcccttatac catttcgggc tattaccgcg
    29281 cccctgccca caacgcgcag gcctttaccg cgcaagggtt ttaccgcaca ggcgacaatg
    29341 tcaggctgga tgaggtgggg aacctgcacg ttgagggacg cataaaagag cagatcaacc
    29401 gcgccggaga aaaaatagcc gcggctgaag tggaatcggc actgctgcgt ttagcggaag
    29461 tgcaagattg cgcggtggtc gccgcgccgg acacgctgct tggcgagcgg atttgcgcgt
    29521 ttatcatcgc gcagcaggtg ccaactgact atcagcagtt gcgtcaacaa ctgacccgta
    29581 tggggctcag cgcgtggaaa attcctgacc aaatcgagtt tctggaccac tggccgctca
    29641 ccgccgtcgg caagatagac aaaaaacgcc tgacggctct cgccgtcgac cgttatcgcc
    29701 attctgccca ataagcgcaa accgacccga aacaggttga aataaacccg tttcgggtag
    29761 caccactatt agaaatagtt atcattttca attcaccatt gtcggtattt ttggcgtttc
    29821 gccgtcttac agggactcac aacaatgaaa atgacacggc tttatcctct ggccttgggg
    29881 ggattattgc tccccgccat tgctaatgcc cagacttcac agcaagacga aagcacgctg
    29941 gtggttaccg ccagtaaaca atcttcccgc tcggcatcag ccaacaacgt ctcatctact
    30001 gttgtcagcg cgccggaatt aagcgacgcc ggcgtcaccg ccagcgacaa actccccaga
    30061 gtcttgcccg ggctcaatat tgaaaatagc ggcaacatgc ttttttcgac gatctcgcta
    30121 cgcggcgtct cttcagcgca ggacttctat aaccccgccg tcaccctgta tgtcgatggc
    30181 gtccctcagc tttccaccaa caccatccag gcgcttaccg atgtgcaaag cgtggagttg
    30241 ctgcgaggcc cacagggaac gttatatggc aaaagcgctc agggcgggat catcaacatc
    30301 gtcacccagc agccggacag cacgccgcgc ggctatattg aaggcggcgt cagtagccgc
    30361 gacagttatc gaagtaagtt caacctgagc ggccccattc aggatggcct gctgtacggc
    30421 agcgtcaccc tgttacgcca agttgatgac ggcgacatga ttaaccccgc gacgggaagc
    30481 gatgacttag gcggcacccg cgccagcata gggaatgtga aactgcgtct ggcgccggac
    30541 gatcagccct gggaaatggg ctttgccgcc tcacgcgaat gtacccgcgc cacccaggac
    30601 gcctatgtgg gatggaatga tattaagggc cgtaagctgt cgatcagcga tggttcacca
    30661 gacccgtaca tgcggcgctg cactgacagc cagaccctga gtgggaaata caccaccgat
    30721 gactgggttt tcaacctgat cagcgcctgg cagcagcagc attattcgcg caccttccct
    30781 tccggttcgt taatcgtcaa tatgcctcag cgctggaatc aggatgtgca ggagctgcgc
    30841 gctgcaaccc tgggcgatgc gcgtaccgtt gatatggtgt ttgggctgta ccggcagaac
    30901 acccgcgaga agttaaattc agcctacgac atgccgacaa tgccttattt aagcagtacc
    30961 ggctatacca ccgctgaaac gctggccgca tacagtgacc tgacctggca tttaaccgat
    31021 cgttttgata tcggcggcgg cgtgcgcttc tcgcatgata aatccagtac acaatatcac
    31081 ggcagcatgc tcggcaaccc gtttggcgac cagggtaaga gcaatgacga tcaggtgctc
    31141 gggcagctat ccgcaggcta tatgctgacc gatgactgga gagtgtatac ccgtgtagcc
    31201 cagggatata aaccttccgg gtacaacatc gtgcctactg cgggtcttga tgccaaaccg
    31261 ttcgtcgccg agaaatccat caactatgaa cttggcaccc gctacgaaac cgctgacgtc
    31321 acgctgcaag ccgcgacgtt ttatacccac accaaagaca tgcagcttta ctctggcccg
    31381 gtcgggatgc agacattaag caatgcgggt aaagccgacg ccaccggcgt tgagcttgaa
    31441 gcgaagtggc ggtttgcgcc aggctggtca tgggatatca atggcaacgt gatccgttcc
    31501 gaattcacca atgacagtga gttgtatcac ggtaaccggg tgccgttcgt accacgttat
    31561 ggcgcgggaa gcagcgtgaa cggcgtgatt gatacgcgct atggcgcact gatgccccga
    31621 ctggcggtta atctggtcgg gccgcattat ttcgatggcg acaaccagtt gcggcaaggc
    31681 acctatgcca ccctggacag cagcctgggc tggcaggcga ctgaacggat gaacatttcc
    31741 gtctatgtcg ataacctgtt cgaccgtcgt taccgtacct atggctacat gaacggcagc
    31801 agcgccgtcg cgcaggtcaa tatgggtcgc accgtcggta tcaatacgcg aattgatttc
    31861 ttctgattat tgtaaaaggg ataccgaaaa ggtatccctt ttacaccact agttaaaacc
    31921 agtaactcag cagagtcgca aaaatattaa tccatagtga ttatttaaac aatgaaattg
    31981 cgattaggat aaatagattt aactttctcg ttcctttctc tccttatact aaagaaataa
    32041 tcatatcaaa ataaaaattc acaacagtgc aacattaaaa aatacaacca acaaacaatc
    32101 ctatatacaa ggcacatctc cagaatataa aagcacagac aaacaaccta aaaaaacaac
    32161 cccatacata taaattattt tataggtaaa atagattata tattctcata gctaccataa
    32221 actatactag cctgaactat atttattctg ctacaatcaa tgcatacata acacaaatat
    32281 cactcaggta cactactcaa accacgctgg gatttttcct caagttataa tcatcacccc
    32341 gaaaatcatt cggcatttac tcattaaata gtcaccccat aggcctgtac atgtttactc
    32401 agaaatatac atccttttct ctgtcataaa ccctctgatt aatcataaat aaatacttgt
    32461 gacaccaatc tttttcctta acggaacgaa ttgttgtgta gaaggagata atattatgtc
    32521 aaaaaaatat cagccattgc ttataactca ttatatgtca acatgggtca ctataacgga
    32581 agcagttgag atcactacca aagccataaa acaaaaaatt actcctagcg atatttatcg
    32641 tcatgccttg agtggcaaca tcctactatc gatctatttc cagtctcctg tgatacttaa
    32701 gaagatacaa acttttaatg gaaaaataaa attcaggcag tttgtgggag acctacttga
    32761 taaactatgc atgcttgaca gtgacggttt tatttatggt caaaatttaa gactctgtac
    32821 agaagccaga tatatttgtc ctgtgcaaca aattatagat acccccctgt tacgcaaact
    32881 caaccagttt cgtacgtttg ttcgtaatgt ccgcccgggt gatgaactgg atgtccaggc
    32941 acaagttagt gaaaaaaatt taaccccgcc gccgggtaac agcagtggca accttgagca
    33001 acagatagcc agtacttcac agctaattgg atctctgctc gccgaagata tgaacagcga
    33061 gcaagcggca aacatagcac gtggatgggc ctcttctcag gcttcagggg taatgacaga
    33121 ctggttaagc cgcttcggta ccgcaagaat cacgctgggc gtggatgaag atttcagcct
    33181 gaagaactcc cgtgacggca accctcgaaa atggcgattc gatgcaacaa acagtgaact
    33241 atgtgccgaa cgtcacgaat gctgaaatca cgctggcagc ctcgaaggat ccggtgattg
    33301 ccgacaataa cgatctcacg acactaacag caccgtcgct gatacagagg gcaatgcgat
    33361 agccaacact gaggtaacat ttactctacc ggaagatgtg aaggcgaact tcacgctgag
    33421 cgatggcgac aaagcggtta ctgatgccga tggcaaagcg aaagtcacgc tgaaaggtac
    33481 aaaagcaggc gctcataccg tgacagcatc gatggttggc ggtaagagtg agcagttggt
    33541 ggtgaacttt actgcggata cgctcactgc gcaggttaat cttaacgtta ccgaggacaa
    33601 tttcatcgcc aataacattg gaatgaccag gctacaagca acagtgactg atggaaacgg
    33661 caacccagta gaaggtataa aagttaattt ccgtggaacc tccgtcacgc taagcagcac
    33721 cagcgttgaa acggatgatc aggtttttgc tgaaattctt gtgacaagca ccgaggtcgg
    33781 actaaaaaca gtttcagcct ctctggcaga taaacctact gaagtcatct cgcgattact
    33841 gaatgccaag gtagatgtta attctgcgac gattaccagt caggagatac ctgaaggtca
    33901 ggtcatggtc gcacaagaca tagcagttaa agctcacgtt aacgaccagt ttggcaaccc
    33961 ggtgacgcat caacccgcga cattcagtgc agcgccatcc tcgcaaatga tcatcagcca
    34021 gaacacggtc tctactaata cgcagggagt agccgaggtc accatgacgt ctgaaagaaa
    34081 cggctcgtat actgtaaaag catccctagc gaatggagct tcacttgaga aacaactgga
    34141 ggctattgat gaaaaactga cactcacgtc cagtccgctt atcggtgtca atgctcctaa
    34201 aggcgctact ctgacggcaa cgctaacctc tgcaaatggc actccagtgg agggtcaggt
    34261 catcaacttt agcgtaacgc tagaaggtgc gacgttaagt ggcggaaaag tgagaaccaa
    34321 ctcttcagat caggctccag tcgttctgac cagcaataaa gtcggtacat atacggtgac
    34381 tgcatcgttc cataacggcg tcacaataca gacacagaca accgtgaagg ttactggcaa
    34441 cccaagcacc gcacatgttg ctagctttat cgctgatccg tcgactatcg ccgccaccaa
    34501 cagtgattta agtaccttaa aggcaacggt tgaggatggc agtggtaacc tgatcgaagg
    34561 tctcactgtg tacttcgcct taaaaagcgg ctccaccaca ttaacgtcat taacagccgt
    34621 gaccgatcaa aacggaatcg cgacaacaaa cgtgagatga gcgataacag ggagcgtcac
    34681 tgtaagcgca gtcataagcg caggtggaat gcaaacagta gatatatcgc tagtggcagg
    34741 cccagcagac gcctcgcagt ccatccttaa gaacaaccag tcatcactga aaggggactt
    34801 taccgatagt gctgagctac atcttgttct gcacgatata tcaggcaatc cgatcaaagt
    34861 ttcttaaggg atagaatttg tgcaatcagg tacaaacgtg ccctatatga aaattagcgc
    34921 aattgattac agtcaaaata tcaacggtga ttacaaagct actgttacag gaggcggaga
    34981 gggtatcgca acgctgatcc ccgtattgaa tggtgttcat caggcgggtc tgagtaccac
    35041 gatagaattc attagcgcgg aaaccagacc aatgacgggt acagtgtcag tgaatagtgc
    35101 aaacctaccg acagcttcat tcccttcgca gggatttacc ggggcgtatt atcagttgaa
    35161 taatgacaac tttgcaccag gaaaaacggc ggctgattat tcgttttcaa gctcggcctc
    35221 ctgggtaggc gttgatgcta ctggtaaagt gacattcaaa aatgacggtg atagcaatac
    35281 tgtaataatc acagcgcccc caagatccgg tggtgctatt taccaaacag ttcctcctga
    35341 atcgcgttcg gtgtgactat gatcattttc ggtgagtatt gctttgatcc aaaggctggt
    35401 tttctgtgat gattgaccag cctcagagta ttgatgacac caccgttcat aacagatcgg
    35461 cattactatg cataagtact gcctcaaatt ctcgccaaaa cactttttaa tgcctttgcg
    35521 aattcatcca gacttatatt gtcaattttt tgcccaacga cgactgactc cgaaacatcg
    35581 gccattgcgg gccatcgcgt tttgtaatca gcataaattg caacaacagg ggtattatag
    35641 gcacttgcca tatgtaatat tgaggtgtca ggagttattg caatataagc atcttttatg
    35701 attgctgctg aacgtttaat cgagggtgat aaggataaac ggtagacatt attataacaa
    35761 tccactaatg ccctggcttt atcttcccct ttgggtccat aaacgatcac tattggaata
    35821 tctgtttcac tttgaatttt tgctattaga ttttctgcaa tcgataatga aaatgtacgt
    35881 tcctgcgagc taccttctaa attgagcgca atgtaagatc ctaacgatcg catttcctcg
    35941 cgtacctcat cgagtacatc atcgcttaat ggcaattcat atattgacct gactgccgga
    36001 aaacccgcct cacgcatcat aaatgcccat gtcatgggta caggagcccg gagattctga
    36061 tccatccggg acgcgttctt acacaaaggg gaatagcact tcatggttaa accgacgacc
    36121 tggaaattcg tttttgcttt caactgactg ataaatatca tcgttttcag gttcttttta
    36181 cgcatcgcct ctatacaaag atccggcgta ccatattgca gtgttatgtt cttcgctaaa
    36241 tcttttattt cttttaatgt tgcgtgatcc tgcatagtca ttgtgactaa tgttaattta
    36301 gtctgttcaa gtttgagcgc attaaagact tctaaattaa ttgtcgacgt aacaattaat
    36361 agatgcttaa ttttatgcaa ttcaagcgcc cgaataacag gaaagatggc catagcatcg
    36421 ccaatctgat cgggaatatg tatgacaaca aagtctgttt tttcaatatt aaaattataa
    36481 gttttataat cgtagtaact aaatgcaata cgtctcaaca atgatactaa aaacataact
    36541 aacctcgcct ccctactggt tataatgcaa tgcagtctat cagaatcatc agggtgcaat
    36601 tttgtgcata tgcggacttt tatgtttcat atctcgaacc tgtgggccct ctgcttaatc
    36661 cttaaacaac accagcaact cctgcgcttt catcttccat cgaatttttc atgttgccgc
    36721 taatcagcca taaaatcatt tgcagatgcg ctctgtcgag gtagtctcat aaggttcgtt
    36781 tatagatcga cggcaatgtg agttaccttt tccatactaa ttataaaaag acagtacaaa
    36841 caggatcatt atggactcca cgctcatctc cactcgtccc gatgaaggga cgctttcgtt
    36901 aagtcgcgcc cgacgagctg cgttaggcag tttcgctggt gccgtcgtcg actggtatga
    36961 ttttctactc tatggcatta ccgccgcact ggtgtttaat cgcgagtttt tcccgcaagt
    37021 aagcccggcg atgggaacgc tcgccgcatt tgccaccttt ggtgtcggct tccttttccg
    37081 accgctcggc ggtgtcattt tcggtcactt tggcgaccga ctgggacgta agcgcatgtt
    37141 aatgctgacc gtctggatga tgggcatcgc gacagcctta attggtattc ttccttcatt
    37201 ctcgaccatt gggtggtggg cacctatttt gctggtgaca ctgcgtgcca ttcagggatt
    37261 tgccgtcggc ggcgaatggg gaggcgcagc gttgctttcc gttgaaagtg cgccgaaaaa
    37321 taaaaaagcc ttttacagta gcggtgtaca agttggctac ggtgtaggtt tactgctttc
    37381 aaccggactg gtttcattga tcagtatgat gacgactgac gaacagtttt taagctgggg
    37441 ctggcgcatt cctttcctgt ttagcatcgt actggtactg ggagcattgt gggtgcgcaa
    37501 tggcatggag gagtccgcgg aatttgaaca acagcaacat aatcaagcgg ccgcgaaaaa
    37561 acgcatcccg gttatcgaag ctctgttacg acatcccggt gctttcctga agattattgc
    37621 actacgactg tgcgagttgc tgacgatgta cattgttact gcctttgcac ttaattattc
    37681 aacccagaat atggggttac cgcgcgaact tttccttaat attggtttgc tggtaggtgg
    37741 attaagctgc ctgacaattc cctgttttgc ctggcttgcc gatcgttttg gtcggcgcag
    37801 ggtttatatt acaggcgcgt tgatcggaac gttgagcgca tttcctttct ttatggcgct
    37861 tgaagcacaa tctattttct ggatagtttt cttctccata atgctggcaa acattgcgca
    37921 tgacatggtg gtgtgtgtgc aacaaccgat gtttaccgaa atgtttggtg ccagttatcg
    37981 ctacagtggt gctggagtcg gttatcaggt tgccagtgtg gttggcggtg gatttacacc
    38041 ttttattgcc gctgcactca tcacttactt tgccgggaac tggcatagcg tcgccattta
    38101 tttgctggct ggatgcctga tttctgcaat gaccgcttta ttgatgaaag acaatcaacg
    38161 ctcgtgatag cctggcgaag atcatccgat cttcgcctta tacttttgtt tcacattcct
    38221 gtgacatact atcggatgtg cggtaattgt atggaacagg agacacacat gaataataag
    38281 ggctccggtc tgaccccagc tcaggcactg gataaactcg acgcgctgta tgagcaatct
    38341 gtagttgctt tacgcaacgc cattggcaaa tatattacaa gtggcgaatt acctgatgaa
    38401 aacgcccgca aacaaggtct ttttgtctat ccatcactga ccgtaacctg ggacggtagc
    38461 acaactaatc cccccaaaac gcgcgcattt ggtcgtttta cccacgcagg cagctacacc
    38521 accacgatta ctcgccctac tctctttcgt tcgtatctca atgaacaact tacgttgctg
    38581 tatcaggatt atggtgcgca tatctcggtg caaccctcgc agcatgaaat cccttatcct
    38641 tatgtcatcg atggctctga attgacactt gatcgctcaa tgagcgctgg gttaactcgc
    38701 tacttcccga caacagaact ggcgcaaatt ggcgatgaaa ctgcagacgg catttatcat
    38761 ccaacggaat tctccccgct atcgcatttt gatgctcgcc gggttgattt ttccctcgca
    38821 cggttgcgcc attataccgg tacgccagta gaacattttc aaccgttcgt cttgtttacc
    38881 aactacacac gttatgtgga tgaattcgtt cgttggggat gcagccagat cctcgatcct
    38941 gatagtccct acattgccct ttcttgtgct ggcgggaact ggatcactgc cgaaaccgaa
    39001 gcgccagaag aagccatttc cgaccttgca tggaaaaaac accagatgcc agcatggcat
    39061 ttaattaccg ctgatggtca gggtattact ctggtgaata ttggcgtggg accgtccaat
    39121 gctaaaacca tctgcgatca tctggcagtg ctacgcccgg atgtctggtt gatgattggt
    39181 cactgtggcg gattacgtga aagccaggcc attggagatt atgtccttgc acacgcttat
    39241 ttacgcgatg accacgttct tgatgcggtt ctgccgcccg atattcctat tccgagcatt
    39301 gctgaagtgc aacgtgcgct ttatgacgct accaagttag tcagcggcag gcctggtgaa
    39361 gaagtcaaac agcggttacg tactggcacg gtggtaacca cagatgacag gaactgggag
    39421 ttacgttact cagcttctgc acttcgtttt aacttaagcc gggccgtagc aattgatatg
    39481 gaaagtgcaa ccattgccgc gcaaggatat cgtttccgcg tgccatacgg gacactactg
    39541 tgtgtttcag ataaaccgtt acatggtgag attaagcttc ccggccaggc taaccgtttt
    39601 tatgaaggcg ctatttccga acacctgcaa attggcattc gggcgatcga tttgctgcgc
    39661 gcagaaggcg accgactgca ttcacgtaaa ttacgaacct ttaatgagcc gccgttccga
    39721 taataagtta tgaaccttct tatcagaaat agatgtgaag gattaagtaa gacatctggc
    39781 aaatagcctg caataaacgc gggctgtttg cttccttggg cagatgcgag ttttattatc
    39841 gtcttaatga tttccacata ttaaaagcaa gtatgctttc aaaacacaat tataaaaaat
    39901 cccgccaaca acattagttt ttataaaatt aaatataaga ttatggcttt agaatatttt
    39961 tatttctaat agacgagatt tttcctgtta tgatataata tgccgaatta acacatgtta
    40021 acgatttacc agtaatgtaa ataaattttc gaggagatca ttccagtggg acgtaaatgg
    40081 gccaatattg ttgctaaaaa aacggctaaa gacggtgcaa cgtctaaaat ttatgcaaaa
    40141 ttcggtgtag aaatctatgc tgctgccaaa caaggtgaac ccgatccaga attaaacaca
    40201 tctttaaaat tcgttattga acgtgcaaaa caagcacaaa ttccaaagca cgttattgat
    40261 aaagcaattg ataaagccaa aggcggcgga gatgaaacgt tcgtgcaggg acgttatgaa
    40321 ggctttggtc ctaatggctc aatgattatc gctgagacat taacttcaaa tgttaaccgt
    40381 acgattgcta acgttcgcac aattttcaat aaaaaaggcg gcaatatcgg agcggcaggt
    40441 tctgtcagct atatgtttga caatacgggt gtgattgtat ttaaaggaac agaccctgac
    40501 catatttttg aaattttgct tgaagctgaa gttgatgttc gtgatgtaac tgaagaagaa
    40561 ggtaatattg ttatttatac tgaacctact gaccttcata aaggaatcgc ggcgctaaaa
    40621 gcagctggaa tcactgagtt ctcaacaaca gaattagaaa tgattgctca atctgaagtt
    40681 gagctttccc cagaagattt agaaatcttt gaagggcttg ttgatgccct tgaagatgac
    40741 gacgatgtac aaaaagttta tcataacgtc
//
LOCUS       DAPOXO010000041        40043 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPOXO010000041 DAPOXO010000000
VERSION     DAPOXO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40043
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.041"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            113..3871
                     /gene="yfaL"
                     /locus_tag="ROH59_002538"
     CDS             113..3871
                     /gene="yfaL"
                     /locus_tag="ROH59_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HDX4805005.1"
                     /translation="MRIISLRKEYLSLLPSMIASLFSANGAAAVIDSCQGYDIKASCQ
                     ASRQSLSGNIQDWSIADGQWLIFSGMVNNASGGAVFLQHSAEFTISPQNETGMTLFAD
                     NSVSGEYNNGGAIFAKENSTINLANVIFDSNVAGGYGGAIYSAGTNDTGAADLRVTNA
                     VFHNNIANDGKGGAIYTINNDVYLSDDAFNNNQAYTSTSYSDGDGGAIDVTDNSTDKT
                     HLSGKTIINNTSFTNNYAEGYGGAIYTSSTTSPYLIDISVDDNYDQNNGVMIDENNSA
                     SGYDHSATAAAGGFMYIGHSVAEFNIAADKTLVIGNTSNDGAIDSLAGTGVIVKEGAG
                     ELVLNADNNAFTGEMSIQNGEVTLGRSDELMNVGDTHCQSDPQDCFGLMVGSTVHSEY
                     QAELNVGNTQQTFVHSLTGFANGILNIDAGGNVTVNQGGFSGSIQGEGQLTVAQDGSY
                     LLTGAQSMALTGDIVVEDNAVLSLAGNQADLRAMQSDPQSIVLNGGVLDLSDFTTWDG
                     DSSYNDGLQISGSGGTVIGSNDVVDISSGDDLHIGGSDASQNGVYVVINAGDQRVTLA
                     NNNGYLGNTQIASGTLEVSDNSQLGDTSYNRSVIFTDPQQHSEMDVTTDVDTRSATTG
                     QGRNIEMRADGEIHVEDGVDTQWGGLMADSTGQQLDSVSTLTKSGGGTLELTASGTAT
                     SAVRVEDGTLKGEAENIIPYVSSLWVGEDGVFETGQNQDIRSIDATSGGDIDITDGTV
                     LRLTQQDTNQALDASLFSGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLT
                     NTSGAVSLQNGIAGDTLTVNGDYTGGGTLLLDSELNGDDSASDQLVLNGNTAGNTTVV
                     INPITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWY
                     LRSQEVNPTPPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYFNNLRAANQ
                     AFVMERRDHAGGDGQTLNLRVIGGRYHYTAAGQLAQHEDTSTVQLSGNLFSGHWGDDG
                     EWMLGIVGGYSDNQGDSRSNMTGTRADNQNRGYAVGLTSSWYQHGNQKQGAWLDSWLQ
                     YAWFNNDVSEQDDGVDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFT
                     AANHARVSQSQGDDIQMRLGLHSEWRTAVGVTPTLDLNYYHDPHATEIEEDGSTISDD
                     AVKQRGEIKVGITGNISQRVSLRGSVAWQKGSDDFAQMAGFLSMTVKW"
     gene            complement(4011..4733)
                     /locus_tag="ROH59_002539"
     CDS             complement(4011..4733)
                     /locus_tag="ROH59_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HDX4805006.1"
                     /translation="MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNP
                     ITNTFKLGPGVDVNYMLHTQNK"
     gene            4880..7507
                     /gene="gyrA"
                     /locus_tag="ROH59_002540"
     CDS             4880..7507
                     /gene="gyrA"
                     /locus_tag="ROH59_002540"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HDX4805007.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTSEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            7656..9344
                     /locus_tag="ROH59_002541"
     CDS             7656..9344
                     /locus_tag="ROH59_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 domain-containing protein"
                     /protein_id="HDX4805008.1"
                     /translation="MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYSGSGPEKTLSP
                     LVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIE
                     GSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPL
                     LFAATSDSQLSKTEISSIKINSETIPVYQLRYNGNNVLMFATYQDKILAFSSSDMLFK
                     DDQQDTEATAIASDLLSGKKRWETRFGLEARTAEKTPVRQRIVVSARLLGFGYQRLMP
                     SFAGVRFEMGNDGWHSFLALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAE
                     EMLSHISQENDKLNGALDGGAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNI
                     GAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLA
                     MQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGMAKLLRNETLT
                     SLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGVAWQWLPITWQPL"
     gene            9341..9964
                     /locus_tag="ROH59_002542"
     CDS             9341..9964
                     /locus_tag="ROH59_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1175 domain-containing protein"
                     /protein_id="HDX4805009.1"
                     /translation="MRHGLLALICWLYCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQ
                     GPSPRWYQQDCAGLVRFAANEALKVHDSKWLKSNGLSNQYLPPEMTLTPEQRQLAQNW
                     NQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYIIYH
                     TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR"
     gene            9988..14502
                     /locus_tag="ROH59_002543"
     CDS             9988..14502
                     /locus_tag="ROH59_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HDX4805010.1"
                     /translation="MGTGLANAEDSLPSSNYVPPAGGTFFLLADSSFSSSEEAKVRLE
                     APGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWL
                     WDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIVKPSRYVQNSQFSPLKKYPLV
                     EQFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGKQEPGLYLVEAMVGGYR
                     ATTVVFVSDTVALSKVSGNELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDGSGT
                     LQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKV
                     MGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTLDARNGGQGSFRLPENAVAGG
                     YELRLAYRKQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVK
                     DARVQLSLRAQQLSMVGNDLRYAGRFPVSMEGSETVSDDNGHVALNLPAADKPSRYLL
                     TVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVT
                     YEWLRLEDRTSHSGELQSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKDST
                     SHSGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTL
                     QRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTH
                     YQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRT
                     SSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKA
                     YFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRMGDKPAAG
                     LFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQV
                     QDSISTKLSFVDNRWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLD
                     ALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGAR
                     FTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRA
                     LVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTSDINDSMILDTPESPLADA
                     VANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAAIL
                     SGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVP
                     DILSFGDELPPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSN
                     EIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQL
                     LEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAP
                     GSEWIGMQVK"
     gene            14503..16152
                     /locus_tag="ROH59_002544"
     CDS             14503..16152
                     /locus_tag="ROH59_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaQ family protein"
                     /protein_id="HDX4805011.1"
                     /translation="MNWYRIVWLLALVTLPTLAEETPLQLALRGAQHDQLYQLSSSGV
                     TKVSVLPDTLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRD
                     SALVRSCGLYFAPQRLHIGADMWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLA
                     TLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTD
                     GTPLWVTGSGTSKTVLTRYATALNRVLPVPTQVASGQCVLVDLFARYPLKKVTEEKST
                     TAVKLGVLNGRYRVTFANGNHMTFVSHGETTLLTVKGKLKLQSHLDREEYVARVLDRE
                     AKSTPPEAAKAMTVAIRTFLQQNADREGDCLTIPDSSATQRVSASPATTGARTMTAWT
                     QDLIYAGDPVHYHGSRATEGTLSWRHATAQAGQGERYDQILAFAYPDNSLSRWGAPRS
                     TCQLLPKAKAWLAKKMPQWRRILQGETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRN
                     FFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            16157..16933
                     /locus_tag="ROH59_002545"
     CDS             16157..16933
                     /locus_tag="ROH59_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HDX4805012.1"
                     /translation="MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASF
                     SQTINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGAGAIRARLRLVLSWDTDNTDLDLHV
                     VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYFGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            complement(17007..18191)
                     /gene="atoB"
                     /locus_tag="ROH59_002546"
     CDS             complement(17007..18191)
                     /gene="atoB"
                     /locus_tag="ROH59_002546"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA acetyltransferase"
                     /protein_id="HDX4805013.1"
                     /translation="MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKID
                     SLHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAI
                     QAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGI
                     TAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDE
                     FPKADSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLNPLARI
                     KSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKTLGFD
                     PEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIER
                     LN"
     gene            complement(18222..19544)
                     /locus_tag="ROH59_002547"
     CDS             complement(18222..19544)
                     /locus_tag="ROH59_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00366 family protein"
                     /protein_id="HDX4805014.1"
                     /translation="MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPI
                     SMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVT
                     FFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
                     LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPK
                     LLMEEADFQKQLPKDAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNL
                     MFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFI
                     NVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVMPAAQALGADLGKSVMAIAYG
                     EQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF"
     gene            complement(19541..20191)
                     /locus_tag="ROH59_002548"
     CDS             complement(19541..20191)
                     /locus_tag="ROH59_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-CoA--3-ketoacid-CoA transferase"
                     /protein_id="HDX4805015.1"
                     /translation="MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQ
                     SENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFDSAMSFALIRGGHIDACVLGGLQ
                     VDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
                     QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL"
     gene            complement(20191..20853)
                     /gene="atoD"
                     /locus_tag="ROH59_002549"
     CDS             complement(20191..20853)
                     /gene="atoD"
                     /locus_tag="ROH59_002549"
                     /EC_number="2.8.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase subunit alpha"
                     /protein_id="HDX4805016.1"
                     /translation="MKTKLMTLQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGV
                     RDLTLIANDTAFVDTGIGPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGT
                     LIEQIRCGGAGLGGFLTPTGVGTVVEEGKQTLTLDGKTWLLERPLRADLALIRAHRCD
                     TLGNLTYHLSARNFNPLIALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQE
                     SK"
     gene            complement(21049..22434)
                     /gene="atoC"
                     /locus_tag="ROH59_002550"
     CDS             complement(21049..22434)
                     /gene="atoC"
                     /locus_tag="ROH59_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetate metabolism transcriptional
                     regulator AtoC"
                     /protein_id="HDX4805017.1"
                     /translation="MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLF
                     ADIHPDVVLMDIRMPEMDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDY
                     VIKPFDLDELNLIVQRALQLQSMKKEIRHLHQALSTSWQWGHILTNSPAMMDICKDTA
                     KIALSQASVLISGESGTGKELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHE
                     KGAFTGAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIK
                     VDIRVIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDISLLANHFLQKF
                     SSENQRDIIDIDPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQ
                     PVCNAGEAKTAPVGERNLKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYK
                     LQEYGIDPADV"
     gene            complement(22431..24257)
                     /gene="atoS"
                     /locus_tag="ROH59_002551"
     CDS             complement(22431..24257)
                     /gene="atoS"
                     /locus_tag="ROH59_002551"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     AtoS"
                     /protein_id="HDX4805018.1"
                     /translation="MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVL
                     SEKEKKLSAVVNLLNQALGNRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAG
                     YYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMI
                     PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANI
                     DIITDGLSTLAQNIPTRLPQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVI
                     AIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALE
                     ISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGEL
                     MAGVAHEVRNPLTAIRGYVQILRQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRP
                     RHSQWQQVSLNALVEETLVLVQTAGVQARVDFISELDNELSPINADRELLKQVLLNIL
                     INAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPFFTTKASGTGL
                     GLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV"
     gene            24424..27273
                     /gene="rcsC"
                     /locus_tag="ROH59_002552"
     CDS             24424..27273
                     /gene="rcsC"
                     /locus_tag="ROH59_002552"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HDX4805019.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQTDVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVNKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLNKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRES"
     gene            complement(27473..28123)
                     /gene="rcsB"
                     /locus_tag="ROH59_002553"
     CDS             complement(27473..28123)
                     /gene="rcsB"
                     /locus_tag="ROH59_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HDX4805020.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(28140..30812)
                     /gene="rcsD"
                     /locus_tag="ROH59_002554"
     CDS             complement(28140..30812)
                     /gene="rcsD"
                     /locus_tag="ROH59_002554"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HDX4805021.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDTWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGNNENEKEGTDSVSIHFNS
                     TKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTESVPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMTFMKNIGDALKEPAQSLAESAAKLNAPEGKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETELFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPE
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
     gene            31551..32672
                     /gene="ompC"
                     /locus_tag="ROH59_002555"
                     /pseudo
     CDS             31551..32672
                     /gene="ompC"
                     /locus_tag="ROH59_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311131.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
     gene            32784..33839
                     /gene="apbE"
                     /locus_tag="ROH59_002556"
     CDS             32784..33839
                     /gene="apbE"
                     /locus_tag="ROH59_002556"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HDX4805022.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEA
                     MADIVTTSLRIGARTDGAMDITIGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSR
                     GMNGAGQPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDNF
                     KAWMSPQFKSFLISEKN"
     gene            33913..34977
                     /gene="ada"
                     /locus_tag="ROH59_002557"
     CDS             33913..34977
                     /gene="ada"
                     /locus_tag="ROH59_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HDX4805023.1"
                     /translation="MKYAIRLTDDQRWQSVLARDSNADGEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANASEALAAGFRPCKRCQPDKANPLQHRLDKITHACRLLEQETPVTL
                     EALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRELLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDD
                     DATLISELQQMFPAADSAPADLTFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIVIPCHRVVRGDGSLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            34977..35627
                     /gene="alkB"
                     /locus_tag="ROH59_002558"
     CDS             34977..35627
                     /gene="alkB"
                     /locus_tag="ROH59_002558"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HDX4805024.1"
                     /translation="MLDLFADAEPWQEPLAAGAVILHRFAFNAAEQLIRDINDVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHHLCQR
                     AATAAGYPDFQPDACLINRYVPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKVGGHPLTTDCRYNLTFRQAGKKE"
     gene            35703..37346
                     /gene="yojI"
                     /locus_tag="ROH59_002559"
     CDS             35703..37346
                     /gene="yojI"
                     /locus_tag="ROH59_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HDX4805025.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAVT
                     IWGGFILVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFSYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQNGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGQPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
     gene            37564..39210
                     /gene="mqo"
                     /locus_tag="ROH59_002560"
     CDS             37564..39210
                     /gene="mqo"
                     /locus_tag="ROH59_002560"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDX4805026.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNSWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEVLKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL"
     gene            complement(39360..39848)
                     /gene="eco"
                     /locus_tag="ROH59_002561"
     CDS             complement(39360..39848)
                     /gene="eco"
                     /locus_tag="ROH59_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HDX4805027.1"
                     /translation="MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQV
                     IQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVS
                     TMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAV
                     VR"
BASE COUNT         9827 a         9788 c        10732 g         9696 t
ORIGIN      
        1 ataataacaa agtggttatt acatcggggg cagaatttac aaaagaaaaa taccctatat
       61 cgcataatgc gattaaatac gccatcttat agaaaatgat ggttagatga atatgcggat
      121 tatctctcta cgcaaggagt atttatcttt actcccgtca atgattgcat ctcttttctc
      181 tgctaacggt gccgcagcgg tcattgattc atgccaggga tatgatatca aagcgagctg
      241 tcaggccagc aggcaaagcc tttcgggtaa tatacaggac tggagcatcg cggatggaca
      301 atggttgatt ttttcgggta tggtcaataa tgccagcggt ggcgcagtat ttttgcagca
      361 cagtgctgaa tttacgatat caccacaaaa tgaaacaggg atgaccctgt ttgctgataa
      421 ctcggttagt ggcgaatata ataatggcgg ggctatcttt gctaaagaaa actcaacgat
      481 aaatcttgcg aatgttattt tcgacagtaa tgttgcagga ggctatggcg gagcaatcta
      541 ttctgccggt accaatgata ccggtgccgc cgatttacga gtcactaacg ccgtatttca
      601 caataacatc gctaatgacg gcaaaggcgg tgcaatttat accatcaata atgacgtcta
      661 tttaagtgat gatgctttta ataataacca ggcatataca tcaacaagtt atagtgatgg
      721 ggatggcggc gccattgatg ttacggataa tagtacggat aagacacatc tttcaggaaa
      781 aacgataatt aataatacct cctttaccaa taactatgca gaaggttatg gcggagcaat
      841 ttataccagc agcaccacat ccccgtatct tattgatatt tctgttgatg ataattatga
      901 ccaaaacaat ggtgtgatga ttgatgaaaa taacagcgcc tcgggatatg accattcggc
      961 gacggcagcg gcggggggct ttatgtatat cggtcatagt gtggctgaat ttaacattgc
     1021 cgccgataaa acgctggtaa taggcaatac cagcaacgat ggcgcgattg attctcttgc
     1081 cggaacggga gtcatcgtga aagagggagc gggagagtta gtcctcaatg ccgacaataa
     1141 tgcgtttacc ggcgagatga gtatccagaa tggcgaggtg acgttggggc gcagcgatga
     1201 gttaatgaat gtcggcgaca cgcactgtca gagcgatccg caggattgct ttggtctgat
     1261 ggtcggcagc actgttcatt ctgagtatca ggcagaactg aatgttggca atacacaaca
     1321 aacgtttgtg cactcattaa ccggttttgc taatggcatt ttgaatatcg acgcaggcgg
     1381 caatgttacc gtaaaccagg gcggtttttc cggctcgatt cagggtgaag gacagttgac
     1441 ggtagcgcaa gatggcagct atctcctgac aggggcgcag tcgatggcat taaccggcga
     1501 tattgtggtg gaagataacg ccgtattgtc gctggcgggg aatcaggccg atttacgggc
     1561 aatgcagagc gatccgcaat cgatcgtgct aaatggcgga gtattggatc tctctgattt
     1621 caccacctgg gatggcgata gctcatacaa tgacggtctg caaatcagcg gcagcggggg
     1681 gacagtgatt ggcagtaatg atgtcgttga tatcagcagt ggcgatgatt tacatattgg
     1741 cggcagtgat gccagccaga atggcgttta tgtcgtcatt aatgcggggg atcagcgcgt
     1801 aacgctggcg aataacaacg gttatctcgg taatacgcaa atcgcctccg gtacgcttga
     1861 agtcagcgat aattcgcaat tgggggacac aagttacaac cgttcagtga tcttcacaga
     1921 tccccaacaa cacagtgaaa tggatgtgac gactgatgtt gacactcgct cggctacaac
     1981 aggtcagggc aggaatattg aaatgcgcgc tgatggcgaa atacacgttg aggatggcgt
     2041 agatacgcaa tggggcgggt tgatggcgga tagtaccggg caacaactgg atagcgtaag
     2101 cacgttgact aaaagtggcg gcgggacgct ggagttgacc gccagcggca ctgcgacgtc
     2161 tgcggtacgt gtggaagacg gaacgctaaa aggtgaagcg gagaatatta ttccttatgt
     2221 ttcttcactg tgggtggggg aagacggtgt ttttgaaacc gggcaaaatc aggatattcg
     2281 ctcaatcgat gccacctctg gcggcgatat cgacataacc gatggtactg tgttgcgatt
     2341 gacgcagcag gatacgaacc aggcgctgga tgcctcgctg tttagcggcg acggtacgct
     2401 ggtgaatgcc accgatggcg tgacgttgac aggtgagctt aataccaacc ttgaaactga
     2461 cagcctgact tatctttccg acgtgacggt taatggcaat ctgaccaata cgtccggtgc
     2521 tgtcagtctg caaaatggca tcgctggcga cacgctgacg gtaaatggtg attataccgg
     2581 cggcggtacg ctactgctcg acagcgaatt aaacggcgat gactcggcaa gcgaccagtt
     2641 ggtgttgaac ggtaatactg ctggcaatac cacggttgtg attaatccca ttacagggat
     2701 tggtgagccg acatctacag gtattaaagt ggttgatttc gcagctgatc ccacgcagtt
     2761 tcaaaacaat gcgcagttca gtctggcagg aagcggctac gtcaatatgg gggcgtatga
     2821 ctacacgctg gtggaagata acaacgactg gtatctgcga tcacaagaag tcaatccgac
     2881 gccgccgcct gatccagacc cgactccaga tcctgatccc acgccggatc ccgacccaac
     2941 ccccgaccct gaacctacgc ctgcttacca gccggtgttg aatgccaaag ttggtggata
     3001 ttttaataac ctacgtgcgg caaatcaggc atttgtgatg gagcgacgcg atcacgcagg
     3061 tggcgatggt cagacgctga atttacgcgt tatcggcggg cgttatcatt acacggcggc
     3121 agggcagttg gctcagcatg aagacacttc tacggtgcag cttagcggca acctgtttag
     3181 cgggcactgg ggtgatgatg gcgagtggat gcttgggatt gttggtggct acagcgataa
     3241 ccagggcgac agccgctcga atatgaccgg aactcgcgcc gataaccaga accgcggtta
     3301 tgccgttggg ctgacctcaa gctggtatca gcacggtaat cagaagcagg gggcctggtt
     3361 ggatagctgg ctgcaatatg cgtggtttaa caatgatgtt tccgaacaag acgatggagt
     3421 ggatcattac cactcgtcgg ggattatcgc ctcgctggaa gccggttatc agtggttacc
     3481 ggggcgtggt gtggtgattg aaccgcaggc gcaggtgatt tatcagggcg tgcagcagga
     3541 tgattttacc gccgctaacc atgcgcgcgt gtcacaatcg cagggtgatg atattcagat
     3601 gcggttgggt ttacacagcg aatggcgtac tgctgttggt gtcacgccaa cgttagatct
     3661 gaattattat cacgatcccc atgcgacgga aattgaagag gatggcagca ctatcagtga
     3721 cgatgcggtg aagcaacggg gtgaaataaa agtgggaata acgggcaata tcagtcagcg
     3781 agtttcgctg cgcggcagcg tggcgtggca gaaagggagt gatgattttg cccagatggc
     3841 agggtttttg tcgatgacag tgaaatggta atcgctgtct gaccggcact gttgccggat
     3901 gcggcgtaaa cgccttatct ggcctacggg gagcatttgt aggcctgata agacgcggca
     3961 agcgtcgcat caggcttggc gcggttgccg gatgaatcca aacaacaacc tcacttattc
     4021 tgcgtatgca gcatatagtt cacatccacg ccggggccga gcttaaaggt gttagtgata
     4081 gggttgtaat gcagcccggt catatgccgt tctttaagac tggtctgatc cacccagccc
     4141 agcaattctg ccggtttaat aaacttcttc acatcatgtg tacctttagg caccatgcgc
     4201 aaaatatatt cagcaccaac caccgccatc agccatgact tgccgttgcg gttaagcgtc
     4261 gagaaaaaga catcgccgcc cggtttcacc agttgcgcac aggctctgac cactgactga
     4321 ggatcgggga cgtgctccag catctccata caggtcacca cgtcatactg tccggcatgt
     4381 tttgccgcgt gctcttccac ggtttcctgc acgtaatcca cctgaatgcc gctttccagt
     4441 gcgtgcagtt ttgccacctg caatggctca aagcccatat ccagaccggt caccgtcgcg
     4501 ccctcccgcg ccatactctc ggccagaatg ccgccgccac aaccgacatc gagcaccttt
     4561 ttgccaaata aaccgccagc acgctcggca atatagccca gacgcagcgg gttaatgcgg
     4621 tgcagcggtt tgaactcacc ttcaagatcc caccagcggg aggcgacggc ttcaaattta
     4681 gcgatctctt cgtggtctac gttgtggttt accggcgatt tttcggcatt cattggcact
     4741 tctactccgt aattggcaag acaaacgagt atatcaggca ttggatgtga ataaagcgta
     4801 taggtttacc tcaaactgcg cggctgtgtt ataatttgcg acctttgaat ccgggataca
     4861 gtagagggat agcggttaga tgagcgacct tgcgagagaa attacaccgg tcaacattga
     4921 ggaagagctg aagagctcct atctggatta tgcgatgtcg gtcattgttg gccgtgcgct
     4981 gccagatgtc cgagatggcc tgaagccggt acaccgtcgc gtactttacg ccatgaacgt
     5041 actaggcaat gactggaaca aagcctataa aaaatctgcc cgtgtcgttg gtgacgtaat
     5101 cggtaaatac catccccatg gtgacttggc ggtttataac acgatcgtcc gtatggcgca
     5161 gccattctcg ctgcgttaca tgctggtaga cggtcagggt aacttcggtt ccatcgacgg
     5221 cgactctgcg gcggcaatgc gttatacgga aatccgtctg gcgaaaattg cccatgaact
     5281 gatggccgat ctcgaaaaag agacggtcga tttcgttgat aactatgacg gcacggaaaa
     5341 aattccggac gtcatgccaa ccaaaattcc taacctgctg gtgaacggtt cttccggtat
     5401 cgccgtaggt atggcaacca acattccgcc gcacaacctg acggaagtca tcaacggttg
     5461 tctggcgtat atcgatgatg aagacatcag cattgaaggg ctgatggaac acatcccggg
     5521 gccggacttc ccgacggcgg caatcattaa cggtcgtcgc ggtattgaag aagcttaccg
     5581 taccggtcgc ggcaaggtat atatccgtgc ccgtgccgaa gtagaagttg acgccaaaac
     5641 cggacgtgaa accattatcg tccacgaaat tccgtatcag gtgaacaaag cgcgcctgat
     5701 cgaaaaaatt gcggaactgg taaaagaaaa acgcgtggaa ggcatcagcg cgctgcgtga
     5761 cgagtctgac aaagacggta tgcgcatcgt gattgaagtc aaacgcgatg cggtcggtga
     5821 agtggtgctc aacaacctct actcccagac ccagttgcag gtttctttcg gtattaacat
     5881 ggtggcattg caccatggtc agccgaagat catgaacctg aaagacatca tcgcggcgtt
     5941 tgttcgtcac cgccgtgaag tggtgacccg tcgtaccatt ttcgaactgc gtaaagctcg
     6001 cgatcgtgct catattcttg aagcattagc cgtggcgctg gcgaacatcg acccgatcat
     6061 cgaactgatc cgtcatgcgc cgacgcctgc agaagcgaaa actgcgctgg ttgctaatcc
     6121 gtggcagctg ggcaacgttg ctgcgatgct ggaacgtgcg ggcgatgatg ctgcgcgtcc
     6181 ggaatggctg gagccagagt tcggcgtgcg tgatggtctg tactacctga ccgaacagca
     6241 agctcaggcg attctggatc tgcgtttgca gaaactgacc ggccttgagc acgaaaaact
     6301 gctcgacgaa tacaaagagc tgctggatca gattgcggag ctgttgcgta ttctgggtag
     6361 cgccgatcgt ctgatggaag tgatccgtga agagctggag ctggttcgtg aacagttcgg
     6421 tgacaaacgt cgtaccgaaa tcaccgctaa cagcgccgac atcaacctgg aagatctgat
     6481 cacacaggaa gatgtggtgg tcacgctttc tcaccagggt tacgtgaagt atcagccgct
     6541 ttctgaatac gaagcgcagc gtcgtggcgg gaaaggtaaa tctgccgcac gtattaaaga
     6601 agaagacttt attgaccgac tgctggtggc gaacacccac gaccatattc tgtgcttctc
     6661 cagccgtggc cgcgtctatt cgatgaaggt ctaccagttg ccagaagcta ctcgtggcgc
     6721 acgtggtcgt ccgatcgtca acctgctgcc gctggaacag gacgaacgta tcaccgcgat
     6781 cctgccggtg accgagtttg aagaaggcgt gaaagtcttc atggcgaccg ctaacggtac
     6841 tgtgaagaaa accgtcctca ccgagttcaa ccgtctgcgt accgccggta aagtggcgat
     6901 caaactggtt gacggcgatg agctgatcgg cgttgacctg accagcggcg aagacgaagt
     6961 aatgctgttc tccgctgaag gtaaagtggt gcgctttaaa gagtcttctg tccgtgcgat
     7021 gggctgcaac accaccggtg ttcgtggtat tcgtttaggc gaaggcgata aagtcgtctc
     7081 tctgatcgtg cctcgtggcg atggcgcaat cctcaccgca acgcagaacg gttatggtaa
     7141 acgtaccgca gtggcggaat acccaaccaa gtcgcgtgcg acgaaagggg ttatctccat
     7201 caaggttacc gaacgtaacg gtttagtggt tggcgcggtg caggtagatg attgcgacca
     7261 gatcatgatg atcaccgacg ccggtacgct ggtacgtact cgcgtgtcgg aaatcagcat
     7321 cgtaggccgt aacacccagg gcgtaatcct tatccgtact tcggaagatg aaaacgtggt
     7381 gggtctgcaa cgtgttgctg aaccggttga cgaggaagat ctggatacca tcgacggcag
     7441 tgccgcggaa ggggacgatg aaatcgctcc ggaagtggac gttgacgacg agccagaaga
     7501 agaataattt catcgcttca tgccaaaagg gagccatctc ccttttttga attgaaaagt
     7561 ccaggctgta aagtctgggc ttttgtcgta ttagggcgcg gtaaagtttg gctgtgcccg
     7621 taaaaaatgg ctggctatac acaaggaatg tggcaatgag tggtgaaaaa aaggcgaaag
     7681 gctggcggtt ttatggcctt gttggttttg gggcaatagc gctgctatcc gctggcgtat
     7741 gggcattaca atactctggc agtgggccag aaaaaacgtt gtcgccactg gtggtgcaca
     7801 acaatctgca aatcgatctc aatgagccgg acctctttct cgacagcgac tctctgagcc
     7861 agcttcccaa agatctcctt accattccgt ttctccacga tgttctgagc gaagatttcg
     7921 ttttctatta tcagaatcat gccgatcgtc tgggcattga aggcagcatt cgccgcattg
     7981 tctatgaaca cgatctcacg ctgaaagata agctcttttc gtcactctta gaccagcccg
     8041 cgcaggcggc actgtggcac gataaacaag gccatctttc tcattatatg gtgctgatcc
     8101 agcgaagtgg tttaagcaag ctgctggagc cattgctgtt tgccgctacc agcgacagcc
     8161 agttaagtaa aacggaaatc agtagcatca agataaatag tgaaactatt cctgtttatc
     8221 agttgcgcta taacggcaat aacgtcctga tgtttgcgac ttatcaggac aaaatattgg
     8281 ctttttccag ttcggatatg ctgtttaaag atgaccaaca ggataccgaa gccacggcga
     8341 tcgcaagtga tttgttgagt ggtaaaaaac gctgggaaac ccgctttggc ctggaagcgc
     8401 gtactgccga aaaaacgcca gtacgccagc gcatcgtagt cagcgccagg ttgctggggt
     8461 ttggctacca gcgattaatg ccttcttttg ctggcgtacg cttcgaaatg ggtaacgacg
     8521 gctggcacag ttttctggcg ttaaacgatg aatccgccag cgtagatgcc agtttcgatt
     8581 ttacgccggt atggaacagt atgcctgccg gagccagctt ctgtgtggcg gtgccgtatt
     8641 cacacggtat tgccgaagag atgctttcgc acatcagcca ggaaaacgac aagctgaatg
     8701 gggcgttaga cggtggcgcg gggctgtgct ggtatgaaga ctcaaaattg caaaccccac
     8761 tgtttgttgg tcagtttgat ggcactgccg aacaggcgca attgccaggg aaactgttta
     8821 cgcaaaatat tggtgcgcac gaaagcaaag cgccagaagg tgttttgccg gtaagccaga
     8881 ctcagcaggg cgaagcgcaa atctggcgtc gcgaagtgag ttcccgatac ggtcagtatc
     8941 cgaaagcgca ggcggcgcaa cccgatcaat taatgtcgga ttattttttc cgcgtgtcgc
     9001 tggcgatgca aaacaaaacg ctgcttttct ccctcgatga cacgctggtt aataacgccc
     9061 tgcaaacact gaataaaacc cgcccggcaa tggtggatgt aatacccact gatggcatcg
     9121 ttccgctcta tatcaatcca caaggaatgg cgaaactgct gcgtaacgaa acgctgacca
     9181 gtctgccgaa gaatctcgaa ccggtttttt ataacgccgc acaaacttta ttaatgccga
     9241 agctggacgc tttatctcaa caaccgcgtt atgtcatgaa gctggcccag atggaacccg
     9301 gtgtcgcctg gcagtggcta cccataacct ggcaaccgct atgagacacg ggctgctggc
     9361 gctgatttgc tggctgtatt gtgttgttgc ccatagcgaa atgctaaatg tcgaacaatc
     9421 cgggctgttt cgcgcgtggt ttgtgcgcat tgcacaggaa cagctccgcc aggggccaag
     9481 cccacgctgg tatcagcagg attgtgcggg cctggtgcga tttgcggcga acgaggcgct
     9541 gaaagttcac gacagtaaat ggctaaaaag taacggttta tctaaccagt atttgccgcc
     9601 agagatgacg ctaacacctg aacagcgtca actggcgcaa aactggaatc aggggaatgg
     9661 gaaaaccggc ccctatgtga ccgcgattaa tttgattcag tacaacagcc agtttattgg
     9721 ccaggacata aaccaggcac tgcctggcga tatgattttt ttcgatcagg gcgatgccca
     9781 gcacttaatg gtctggatgg ggcgttacat catctaccac accggaagcg ccacgaaaac
     9841 tgacaacgga atgcgcgcag tcagtctgca acaacttatg acatggaagg acacccgatg
     9901 gatacccaac gattccaatc ccaatttcat tggcatttat cgtttaaatt ttctggcgcg
     9961 atagcagcgt gcttgtccct gtctcttgtg ggaacagggc ttgctaatgc tgaggattcg
    10021 cttccttcca gtaactatgt gccgcccgcc gggggaacat tctttttgct cgctgacagc
    10081 agttttagca gcagtgaaga ggcgaaagtg cgactggaag cgccggggcg tgattatcgg
    10141 cgctatcaga tggaagagta cggcggcgtg gacgttcgcc tgtatcgtat tcctgacccg
    10201 atggcatttt tgcgccagca gaaaaacctg catcgcattg tggtgcaacc gcaatatctg
    10261 ggcgacggac tgaacaatac gctgacctgg ctgtgggata actggtacgg caaatctcgc
    10321 cgcgtgatgc agcgtacttt ctcttctcag tcacggcaga atgtgactca ggcgttaccc
    10381 gaattacagc tcggtaatgc cattgttaaa ccttcccgtt atgtacagaa cagccagttt
    10441 tcaccgctga aaaaatatcc acttgtggaa cagttccgct atccactatg gcaggcaaaa
    10501 ccggtcgagc cgcagcaagg ggtaaaactg gaaggcgcat ccagcaattt catctcgccg
    10561 cagccgggca acatctatat tcctctcggc aaacaagagc cgggactgta tctcgtcgaa
    10621 gcgatggtgg gtgggtatcg ggcgacgacg gtggtgtttg tttccgatac cgtggcgctt
    10681 agcaaagtgt caggtaacga gcttctggtg tggaccgcgg ggaaaaaaca gggtgaagcg
    10741 aagcccggct cagagatctt gtggactgac ggtcttggcg tgatgacccg cggtgtgacc
    10801 gatggcagcg gtaccttgca gttacaacat atatcgccag aacgttcata cattctgggt
    10861 aaggatgctg aaggcggcgt ttttgtctcc gagaactttt tctacgaaag cgaaatctac
    10921 aacacccgct tgtatatctt taccgatcgc ccgctatatc gcgcaggcga tcgtgtcgat
    10981 gttaaagtga tgggtcgcga gttccacgat ccgttgcatt catcccccat cgtcagcgca
    11041 ccggcgaagc tttcggtgct ggacgccaac ggcagtctgt tgcaaaccgt caatgtcacg
    11101 ctggatgcgc gtaatggcgg gcaggggagt ttccgcctgc cagaaaatgc cgtcgccgga
    11161 ggttatgagt tacgtcttgc ttaccgcaaa caggtctata gcagcagttt tcgcgtggca
    11221 aactacatca aaccccattt tgagattggt ttagctctcg acaaaaaaga gttcaaaact
    11281 ggcgaagcgg tcagcggcaa actgcaactg ctttacccgg atggcgagcc ggtaaaagat
    11341 gcccgcgtgc agttaagttt gcgcgctcag caattatcaa tggtcggtaa cgatttgcgt
    11401 tatgccggac gtttcccggt gtcgatggaa ggcagtgaaa cggtttccga cgataatggt
    11461 catgtggcgt tgaatctccc cgccgccgat aaaccgagcc gttatttgtt aaccgtctcc
    11521 gccagtgacg gcgcggcgta tcgagttacc accaccaaag agatcctcat tgaacgtggc
    11581 ctggcgcatt actctttaag taccgccgca caatacagta atagcggcga gtcggttgtg
    11641 ttccgttatg ccgcgctgga atcttcaaaa caggttcctg ttacgtatga atggttgcgt
    11701 ctcgaagacc gcacgagtca cagcggagag ctacagtcag gcggcaaatc ctttaccgtc
    11761 aatttcgcta aacctggcaa ctacaatctg acattacgcg ataaagacgg cttaattctc
    11821 gccgggttaa gccatgcagt cagcggtaag gacagcacgt cgcatagtgg tacggtagat
    11881 atcgtggcag ataaaacact gtatcagcct ggcgaaaccg cgaagatgct gattaccttc
    11941 ccggagccaa ttgacgaagc attattgacg ctggaacgcg atcgcgtgga acagcagtcg
    12001 ctgctatcgc atccggcaaa ctggctaacg ctacaacgtt taaacgatac ccagtatgaa
    12061 gcccgcgtac cggtgagcaa ttcctttgcg cctaacatca ctttttcggt gctgtatacc
    12121 cgtaacggtc agtacagttt tcagaacgcc gggattaaag ttgccgttcc ccagctggat
    12181 atccgggtga aaacggacaa aacccattac cagcctggtg aactggtcaa tgtcgaatta
    12241 acctcgtcgc tgaaaggtaa acctgtttct gcgcagttaa cggtaggcgt ggtcgatgaa
    12301 atgatctacg cgctgcaacc ggaaatcgcg ccgaatatcg gcaaattttt ctatccgctg
    12361 gggcgtaaca atgtgcgtac cagctccagt ctgtcgttta tcagctacga tcaggcgctc
    12421 tccagcgagc cggttgcgcc tggcgcgact aaccgcagcg agcggcgagt aaaaatgctg
    12481 gaacgtccac ggcgtgaaga ggtggatacc gcggcctgga tgccgtcact cacaaccgat
    12541 aaacaaggca aagcgtattt cacgttcctg atgcctgatt cgttaacccg ctggcgcatc
    12601 accgcgcgtg ggatgaacgg cgacgggctg gtcgggcagg ggcgtgctta tttgcgttcg
    12661 gaaaaaaatc tctacatgaa gtggagtatg ccaacggtat atcgcatggg tgacaaaccg
    12721 gcggcaggac tgtttatctt cagtcagcag gataacgaac cggtggcgct ggtgactaaa
    12781 tttgcaggtg ctgagatgcg ccagacgctg acgctgcaca aaggggcgaa ttatatttcg
    12841 ctgacgcaga atattcagca atctggcttg ttaagtgcag aactgcaaca aaatgggcaa
    12901 gtacaggaca gcattagcac aaaactgtct tttgtggata acaggtggcc cgttgaacaa
    12961 cagaaaaatg tcatgctcgg cggtggcgat aatgcgctga tgttgcccga gcaggcgagc
    13021 aatatccggc tacaaagtag cgaaacgccg caggagattt tccgtaacaa tcttgatgcg
    13081 ttagtcgatg aaccgtgggg tggcgtgatc aacaccggta gccgtctgat cccgctcagt
    13141 ctcgcctggc gttcgcttgc cgatcatcaa agtgccgccg ctaacgacat tcgtcagatg
    13201 attcaggata accgtctgcg gctgatgcaa ctggcggggc ccggagcgcg ctttacctgg
    13261 tggggtgaag atggcaatgg cgacgccttc ctcacggcat gggcatggta cgccgactgg
    13321 caggccagcc aggcgctcgg cgtaacgcag caaccggaat actggcaaca tatgctcgac
    13381 agttatgccg agcaggcgga caacatgccg ttattgcatc gggcgctggt gctggcgtgg
    13441 gcacaggaga tgaatctgcc gtgcaaaacg ttgttgaaag ggttggatga agctatcgcc
    13501 cggcgcggaa ctaaaactga agatttctct gaggaagaca ccagcgatat caatgacagc
    13561 atgatcctcg atacacctga atctccactg gcagatgcgg tggcaaacgt cttaaccatg
    13621 acgttgctga aaaaagcgca gttgaagtcc actgtgatgc cacaggttca gcaatatgcg
    13681 tgggataaag cagcaaacag caaccaaccg ctggcgcaca cggttgtgct gctcaatagt
    13741 ggaggcgacg ctacccaggc ggccgctatt ttaagtggtt taaccgctga gcaatccacc
    13801 attgagcgcg cgttggccat gaactggctg gcgaaatata tggcgacgat gcctccggtt
    13861 gtgttacctg cgcctgcggg cgcatgggcc aaacataagt taaccggagg aggcgaatac
    13921 tggcgttggg ttggtcaggg cgtgccggac attctctctt ttggtgacga attaccgccg
    13981 caaaacgtgc aggtccgctg gcgtgaaccg gcaaaaacgg ctcaacaaag taatattccg
    14041 gtgaccgttg aacgccagtt gtatcggctt atccccggtg aagaagagat gagctttacc
    14101 ttacagcctg tcaccagcaa tgagattgac agcgatgcgc tgtatctcga tgaaatcacg
    14161 cttaccagcg agcaggatgc cgttctgcgc tatggtcagg tggaagtacc gctgccgccg
    14221 ggggctgacg ttgagcgtac aacctggggc atttcggtca ataaaccgaa cgccggaaaa
    14281 cagcaaggac aactgctgga aaaagcgcgc aatgaaatgg gtgaactggc ctatatggtg
    14341 ccggtaaaag aactgacggg aacggtcacc ttccgccatt tgctgcgttt ctcgcaaaaa
    14401 gggcaattcg ttctgccgcc tgcccgttat gtgcgttcct atgcacctgc acagcaaagt
    14461 gttgcgccag ggagcgaatg gatcgggatg caggtgaaat aagtgaactg gtacagaatc
    14521 gtctggctat tggcgttggt aactctgcca acgcttgcgg aggagacgcc gttacagctg
    14581 gcgctgcgtg gtgcgcagca cgatcaactg tatcagctgt cgtcatcagg cgtgaccaaa
    14641 gtctcggtat tacctgacac gctcaccacg ccattaggga gtttgtggaa actgtatgtt
    14701 tacgcctggc tggaggatac ccatcaaccg gagcagccat accagtgtcg cggcaactcc
    14761 ccggaagagg tttattgttg tcaggctggg gagagcataa cgcgcgattc cgcgctggta
    14821 cgttcctgtg gactctattt tgcgccgcag cggttgcata ttggcgcaga tatgtggggg
    14881 caatactggc aacagcgtca ggcacctgcg tggttagcgt ctcttactac actgaagcca
    14941 gaaacctcgg taacggttaa atcgctgctt gattcattag cgacgttacc tgcgcaaaac
    15001 aaagctcagg aagtcttact ggatgtggtg ctggacgagg cgaaaatcgg tgtcgcatcc
    15061 atgctcggta gtcgggtacg ggtgaaaacc tggagctggt ttgccgatga taaacaggaa
    15121 atccgtcagg gtggttttgc tggctggtta accgatggta caccgctgtg ggttactggc
    15181 agtggcacca gcaaaacggt actgacccgt tatgcgacgg cgcttaatcg ggttttgcca
    15241 gtgccgacgc aagttgccag tgggcaatgt gtgctggtgg atctgtttgc tcgttatccg
    15301 ctgaagaaag ttactgagga aaagagtacg acggcagtca aactaggcgt gctcaatggg
    15361 cgctatcgtg tgacgtttgc caatggtaac cacatgacat ttgtcagcca cggtgagaca
    15421 acgttactga cggtaaaggg caaactgaaa ttacagtcgc atctcgatcg tgaagagtac
    15481 gttgccagag ttctggatcg cgaggcgaaa agtacgcctc ctgaggcagc gaaagccatg
    15541 accgtggcga ttcgcacgtt tttacagcaa aacgccgatc gggaaggcga ttgcctgacc
    15601 atcccggaca gcagcgctac gcagcgtgtt tctgcttcgc cagctaccac gggggcgcga
    15661 acgatgaccg cctggacgca ggatctcatc tatgcgggcg atccggttca ttatcatggc
    15721 agtcgcgcta ccgaagggac gctttcctgg cggcacgcta ctgcccaggc ggggcaggga
    15781 gagcgttatg atcagatact cgcgtttgct tatcccgaca acagccttag ccgctgggga
    15841 gcgccacgct caacctgcca gttattaccc aaagcgaaag cctggctggc gaaaaaaatg
    15901 ccgcagtggc ggcgtatatt acaaggtgag acgggataca acgaaccaga cgtgtttgcg
    15961 gtctgtcgtt tagtctcagg tttcccctat accgatcggc agcagaaacg gctgtttatt
    16021 cgtaatttct ttacgcttca ggatcggctg gatttaaccc atgagtatct gcacctggcc
    16081 tttgatggtt atcccaccgg gcttgatgag aactatatcg aaacgctgac ccgacaatta
    16141 ttaatggact aatgctatgc gaaagatttt tcttccgttg ttactggtgg cgctttcgcc
    16201 tgtcgctcac agtgaaggtg tgcaggaagt cgagattgat gcaccgctct ctggctggca
    16261 tccggcagag ggcgaagatg ccagtttttc acaaacgatc aattacccgg cgtcgtccgt
    16321 caacatggca gatgatcaaa atatctcagc gcagatccgc ggcaaaataa agaattatgc
    16381 tgcggcgggt aaagttcagc agggccggct ggtggtcaac ggtgccagta tgccgcagag
    16441 aattgaatca gatggttctt ttgcacgccc ttatattttc actgaaggca gcaacagcgt
    16501 gcaggtcatc agcccagatg ggcaaagccg acaaaaaatg cagttttact caacgccggg
    16561 tgctggggcg attcgcgcgc gtttacggct ggttctctcc tgggatacgg acaataccga
    16621 cctcgatctt catgtcgtta cgcctgacgg tgaacatgcc tggtacggta acacagtgct
    16681 gaaaaacagt ggcgcactgg atatggatgt cacgacaggg tacggacccg agattttcgc
    16741 catgccagcg ccagttcacg gccgttatca ggtgtatatc aactacttcg gcgggcgcag
    16801 tgaaacggaa ttaactacgg cccaactgac gctgatcacc gatgaagggt cggtcaatga
    16861 gaaacaggaa acttttattg taccgatgcg taatgctggc gagctgacgc tggtgaaaag
    16921 ttttgactgg tgattaatgg ggtaaccttc gccgtcgatg ttcaagaaaa cgcccgataa
    16981 ctttcgctat cgggcgtttt tattggttaa ttcaaccgct caatcaccat cgcaattccc
    17041 tggccgccac caatgcatag tgttgccagc cccagcgttt tatcgcgtgc ctgcattgca
    17101 tgtaatagtg tgaccagaat acgagcacca ctggcaccga taggatgtcc gagcgcgatg
    17161 gccccgccgt tgacattcac tttctcagga tcaaagccca gggttttccc aacggcaagg
    17221 aactgtgcag caaatgcttc attagcctca atgagatcaa tatccgccag ttgcagcccc
    17281 gccagttgta acgctttttg cgtagcaggt actggcccca tacccatcaa tgcggggggc
    17341 acgccaccgc tggcataact tttaatgcgt gccaggggat tcaggcctgc tgccagcgcc
    17401 gcagattctt ccataatcac cagagcggca gcaccgtcgt taatacctga cgcgttcccg
    17461 gcggtgactg ttcctgcttt atcgaaggcc gggcgcaatg cgcctaacgc ttcagccgta
    17521 gaatccgctt tcgggaattc gtcttgactg aagacgaagg ttttcttccg ggtgacaaca
    17581 tttaccggga cgatttcggc tgtaaaagca ccggactcaa ttgcggctgc cgctttacgc
    17641 tgtgaatgta gcgccagttc atcctgcatt tcacgggtaa ttccgtactc tttagccacg
    17701 ttttcggcgg taatccccat atgataacca tgggtggcgc acatcaggcc atcgcgcagg
    17761 attacgtcat aaacctgtcc gtctccaaga cgataaccag agcgtgcttt tgcatcgagt
    17821 aagtagggcg ctaaactcat attttccata ccccccgcca caatgctctg tgcctgacct
    17881 gcctgaatcg cctgtgcagc aagcgccacg cttttcagac ctgaaccgca cactttgttg
    17941 accgtgaatc cgcacaccgt ttcagctagt ccgcttttta gcagcgcctg acgtgccgga
    18001 ttttgcccca gtccggcttg caacacgtta cccataatca cttcatcaac gtgtagtgaa
    18061 tcgatttttg cacgttcaat ggcggcttta attactgtcg cccccaggtc gatggcgctg
    18121 gtggaagcga gtgaaccgtt aaaactaccg atagcagtac gtaccgcact gacgatgaca
    18181 caatttttca ttttatattc cttctgtctg tagggttgcc gtcagaacag cgttaaacca
    18241 atgacgaaaa tgacgccgga gaagagcagg gcagtgatgc aatagcccat gatgtcgcgg
    18301 acaccgagtc cggcgattgc cagtgctggc agcgcccaga acggttgtgc catgttcatc
    18361 cattgctcgc cgtaggcgat cgccattacc gatttaccga gatcagcgcc cagcgcctgg
    18421 gctgcgggca tcacgaacgg cccctgaata acccagtgcc cgccgccaga cggaacggcg
    18481 aagttaatca gtgcagaact aaaaaaggtc atgaccggga aggtgtcttt gttcgcaaca
    18541 ttgatgaaga attcggtaat gagtccgccc agaccggagt gctccatcat cagttggatc
    18601 cccgcgtaga aggggaattg caccagaata ccggcggtac tgcgtgctgc cgcgctgata
    18661 gcacgcatat aagccattgg cgttttatgt agcagcagac ccgcaatcat aaacatcagg
    18721 ttgacggtat tgatggtgat gttgaagcca tgttcgctga agtacatcgc caggtaagcg
    18781 ataccgagtg cgccgatgat caacgtcaga atgcggcttt cttccagtcg ctcggacggt
    18841 ggagcatctt tcggtagttg cttttgaaaa tcagcctctt ccatgagtag tttcggatcg
    18901 atactcacca cgtcagacgg ttttggcatc atcatgcggg tgataaatgg catcaccaca
    18961 atcaacgcca cagtgatgaa aatattaaaa ccactgaaca gagtatcgcc caccgggatc
    19021 agcccagcga tatgctcaac cgggttgccc ggtgttgcag ccaacagagg cattgagcca
    19081 gagaagccgc caccccaggt gagaaaacca atgtaggcgc aggcaatgag caacggataa
    19141 tcagaaccgg gtactcgccg ggcgacttca cgggcgaaca ttgcaccgac aaccaaacca
    19201 aatccccagt tgatgacaca agcgactgaa ccgaagaaag taaccagcat gacgccctgt
    19261 acgggcgtct ttgcggcgga ggcggcagta cgcagcaaac ttttcaccgg agcggagctg
    19321 gcaagggcat gaccggtaac gatgataagc gccatctgca taccaaacgc cagcaagttc
    19381 cagaaaccgt caccccacat tttcaccatg ctgatcggcg tttgtggtgt taaccaaagc
    19441 gcgatcacga atgttagcaa tgtcagcaac atggcaaaga tcagtggatc gggaagccac
    19501 cggctgacaa aacgcgtcat aaaacgcgat atgcgaccaa tcataaatca ccccgttgcg
    19561 tattcagatc ggcagctact tcaaaccgag cttctgtttt ggcacgcacg gtggctaaat
    19621 cacacccgtc ggcaatttcg gtgagccaca ttttgccgtc aataaaacga aagacagcca
    19681 gttcagtaac cagcatatgc accgcatgtt gcgcagtgag tggcatggtg cagcggcgca
    19741 aaatttttgc tgaaccatct ttggcgcaat gttccatggc gatgatcact ttgcgtgacc
    19801 cggtcaccag atccatcgcg ccacccatac cgggcaccat tttcccaggc actacccagt
    19861 tcgcgaggtt tgcttcttcg tctacttgca aaccgccgag cacgcaggca tcaatatgac
    19921 cgccacggat tagcgcaaat gacatggcgc tatcaaacat ggctgcaccg ggtaaaatgc
    19981 cgcacggttg tccgccagca ttcaccagat ctggatgcgc tgttgtgacc gggcctaaac
    20041 cgaggaagcc gttttccgat tgcagagtga tatgaatacc ctccggtaaa taattggcga
    20101 ccattgtggg taaaccgatc cctaagttaa cgatgtcacc atcacgaagc tcttgcgcca
    20161 cacggcgcgc aatacgttgt ttcgcatcca ttatttgctc tcctgtgaaa cgatgatgtg
    20221 gtcgataacg gcaccagggg tgacaatatg gtcaggttgc agctcgccgg tttcgaccag
    20281 ttcatccggc tctaccagcg tgatatcagc cgcaagggct atcagggggt taaagttgcg
    20341 ggcgctaagg tgataggtca ggttgccaag tgtgtcgcaa cgatgagcgc gaattagcgc
    20401 caggtcggcg cgcagcgggc gttcgagcag ccaggtttta ccgtcgagtg tcagtgtctg
    20461 tttgccttcc tctacgacgg tgccgacacc agttggggtg agaaaaccac caagtccagc
    20521 tccgccacag cgaatttgct cgattagcgt accttgcggc accagaacga cgtccatctc
    20581 accagatatc atgcgccgac ctgtttccgg gttggtgccg atatgtgaag caatcacttt
    20641 gcggactcga ccattgacga tgagcggacc gatgccggta tcaacaaacg cggtatcatt
    20701 ggctatcaat gtcaggtcgc gaacaccaga ttccagtaat gcttcaacca ggcgggatgg
    20761 agtgccaatc cccataaatc cgcccaccat gatggtcatg ccgtcacgaa agaagccggt
    20821 ggcgtcttgt aatgtcatca attttgtttt cattttttat ccctcttgca tacaccgttg
    20881 tgggtacagt cagggaatag caaggggagt gccagaatga gattattgaa tgttgttatt
    20941 taactaattg aatagaaaag gataaattag atgggggttc ataaggagaa tgagcggcta
    21001 tgcagaaaat tgcgcactgt gcaaatttct gcatagcaag ttttggcatt atacatccgc
    21061 cggatcgata ccgtattcct ggagtttata catcaatgca cggcgactga tgcccagcat
    21121 taaagcagtg cgggttcggt ttccttcttg ttgttccagc acttccataa tgatgcgttt
    21181 ttcgacgcgt ttaatttcct cttttaaatt acgctcaccg acaggggctg tttttgcttc
    21241 accagcatta cagactggct gacgaatctg cggcggaaga tcctcagaaa aaatgatcgg
    21301 gcctgaattc atcacgacgg cgcgttcaat aacgttggaa agctctcgaa tatttcccgg
    21361 ccatgaccag gcggtaagca gtgacattgc catcggatcg atgtcgataa tatcgcgctg
    21421 attctcacta ctgaattttt gcaaaaagtg attagctaac agggaaatat cttcccggcg
    21481 atcgcgcaga ggcggcagta ttaaatgaat aacgttaagg cgataaaaga gatcttcacg
    21541 gaaggtgcct tctttcacca ttgcctgcaa gtcgcggttg gtggcagcaa tgacgcggat
    21601 atcaactttt atggtctgat ggccgccaat ccgttcaaat tcccgttcct gcagaatgcg
    21661 tagtaatttg gcttgcagta ccagcggcat ttcgccaatt tcgtcgagga gcagagtacc
    21721 ttcgttggca cgttcaaata atccctgacg caaggtttgt gcaccagtaa atgcaccttt
    21781 ttcatgacca aacagttcac tttcgagcaa cgattccggc agtgccgcgc agttgacttt
    21841 aatgaacggc ccctttgccc gccgcgaatt gtagtgaatc gctctggcaa tcaactcttt
    21901 cccggtgccg ctttcaccgc taatcaagac gctggcctga gaaagggcaa ttttggcggt
    21961 gtctttgcag atgtccatca tcgccgggct gttggtgaga atgtgccccc attgccagct
    22021 ggtgctcagt gcctggtgca gatgacggat ctcttttttc attgactgga gttgtaaagc
    22081 gcgctgaacg attaaattca actcatcgag atcaaacggt ttgataacat agtcgaaggc
    22141 tccgcagcgt agtgcttcga cggcggtttc cacttcagca taggccgtca tcagaataac
    22201 gggtgtccgg gtctcatggc tgcgcatctc ctttagtgcc ttgatgccgt ccatctctgg
    22261 catgcggata tccatcaaca ccacgtcagg gtgaatatcg gcaaacaggt gtaatgctgt
    22321 gcgcccgttg ttcgcacaat gtgtttcgaa tccttgtagt gcaaaagcgg tgctcagcat
    22381 acggcgaaca ttatcttcat catccacaat aaggatgcga ttaatagcag tcatacagtc
    22441 tgatttccct gcgggttgat cggtaaaata agcgtgaagg ttgcgccgta gcccggcaaa
    22501 ctggcgacgc gaatatcacc ctgatgggca ttaatgatgc gttgacttaa cgccagacca
    22561 agcccggttc ctgaggcttt ggtagtgaaa aagggatcga agatcttttt ttgcagcgag
    22621 agatcaatgc cactgccgtt gtcctctatc gaaatggcct gttgcgagtc gctatactgc
    22681 caggttcgaa tgcgaatttt ccctcgtgca ctgatagcct ggacggcatt gatcaggata
    22741 ttcagtagta cctgtttgag cagttcacga tcggcgttaa tcgggcttaa ttcattatcc
    22801 agttcgctta tgaagtcgac ccgcgcttgt acgccggcgg tttgtaccag taccagagtt
    22861 tcttcaacca atgcattgag gctgacttgt tgccattgac tgtggcgtgg gcgtgaaaat
    22921 tcgagcaatt gctgaataac tttgttaatt gaatcgattt ctttgagtac tacggacaga
    22981 tattcctgat gtattgggtc acgggtttgt tggcgcaaga tctgtacata accacgaata
    23041 gccgttagcg gattacgtac ttcatgcgcc acgccagcca tcagctcacc cagtgtggcg
    23101 aggcgttctg cttgcgccat gcggcgctgg gtttctttgc gggcagttaa atcagagaaa
    23161 atcaccaaag cacctatcat ttcaccgtgc gtgttatgaa tacgactggt cgtgacactg
    23221 agttcaatgg tgcggtcacg gcctggaaaa ctgatctcca gtgcaacatg ttcggtgcca
    23281 tgttccagcg tatccagtac gggactgtag aactgagtat tgtcgaacaa catggagtaa
    23341 ggctgcccta ccagttcatg acgttgatag ccagtgatga cttctgctgc tgggttcatg
    23401 gtggttacat caccctggcg gtcaatggca atgacgccat cggcagcgtt ttcaataatc
    23461 agatcgttaa gtgttcgcgt ttcacgcagt gcctgggcga ggttgttaac actctgactg
    23521 atttgcccca tttcaccggg caattgtggt aatcgagtgg gaatattttg agccagagtc
    23581 gagaggccat cggtgatgat atctatattg gcgctcaggc gacgggagaa aaggacaatc
    23641 aacagcaggc ttatcagcaa accggcggtg agcacaatga taatcctcac atccattttc
    23701 caggcctggc ggcgaatatc ttcggttaat tcattggccc agatatagcc gaggatttca
    23761 ccattacgct caatgggaat cattgaattc aaaatatcgc cgcgcacctg cctgcctgaa
    23821 taaaccaaag gggtatttgt acgcatgact tcgcgaccag ggtgatctgc ggcaatggta
    23881 acgcccacat tattctgata tagcgctgaa ggcgcgtagg tgattatcgc atccagcgtt
    23941 ttgttgtaat aaccagcgcc gatgccaggg aaggcgtgag tgatattttc ggtaatgggg
    24001 gcaagttctg catttaatgc gcggatacgc tcctcacgcg gtaagtcgat gtagagatcg
    24061 tagcgattgc ctagcgcctg attaagcagg ttgaccacgg cagaaagttt tttctctttt
    24121 tcagataaga ctgctgaacg tccttccgtt tctacgatat aaccaatagt aagcgttggg
    24181 acaatgacca tcaggattgc catcaggatc atttgattgc gtaagcggcg tggataaatc
    24241 cacttcatat aatgcatgct gaaatccact agtcttgtcc ggtatatgac gattatcaga
    24301 ggttaaggtg atgatttctc ggcggtgtat catattccag agaagagaga acattgcggt
    24361 aacacgcttt taccgctacc ttaaccacac tccatcggtc acctgaggcg gagcttcgcc
    24421 cctttgaaat accttgcttc ttttcgtaca accctgaaag cctcgcgcta catgttcaga
    24481 gcattggcgt tagtgctctg gctgttgatt gctttttcat ccgtttttta catcgttaat
    24541 gcgttacatc agcgagaatc ggaaattcgt caggaattta atctgagttc cgatcaggct
    24601 cagcgcttta ttcaacgcac ctctgatgtg atgaaagagc tgaagtacat agctgaaaat
    24661 cgcttatcgg cagaaaacgg tgtgctttcc ccgcgtggac gagaaacgca gacggatgtg
    24721 cctgcgtttg aaccgctgtt tgctgactct gattgttccg caatgagtaa cacctggcga
    24781 ggttctctgg agtcattggc gtggtttatg cgctactggc gcgataattt ttctgcggct
    24841 tacgatctaa accgggtatt tttaatcggc agcgataacc tctgcatggc caatttcggt
    24901 ctgcgtgata tgccagtgga acgcgatacc gcgctaaaag ctttgcatga acgcattaat
    24961 aaatatcgaa atgcaccaca agatgatagt ggcagtaacc tctactggat cagcgaaggt
    25021 ccgcgccctg gcgtcgggta tttttacgcc ttgacgccag tttatctggc gaaccggttg
    25081 caggcgcttt tgggtgtcga gcaaaccatc cggatggaga actttttctt acctggtacg
    25141 ttgccgatgg gggttaccat tcttgatgaa aatggtcata ccctgatttc gcttaccgga
    25201 ccagaaagca aaattaaggg cgatcctcgc tggatgcagg aacgctcctg gtttggctat
    25261 acggaagggt tccgggaact ggtgctgaag aaaaatctgc caccctcatc gctaagcatc
    25321 gtttattcag tgccagttga taaggtgctg gaacgcattc gcatgttgat ccttaacgca
    25381 attttgctga atgtgcttgc cggagctgca ttgtttactc tcgcgcggat gtacgagcgg
    25441 cgtattttca ttccggcgga aagcgacgcc ctgcgactgg aagaacatga gcagtttaat
    25501 cgcaagattg tcgcctccgc gccagtgggt atctgcattt tgcgtaccgc tgatggcgtc
    25561 aatattttaa gtaacgaact ggcgcatact tatctcaata tgcttacgca tgaggaccgc
    25621 caacggctga cacaaattat ctgtgggcag caggtcaatt ttgttgatgt cctgaccagc
    25681 aacaatacca atctgcaaat cagcttcgtc cattcgcgct atcgtaatga aaacgtggcc
    25741 atttgtgtgc tggtggatgt ttcttcgcgc gtgaagatgg aagagtcgtt gcaggagatg
    25801 gcacaagcag cggaacaggc gagccagtca aaatcgatgt tcctggccac cgtcagtcat
    25861 gagctgcgaa cgccgctgta tggcattatc ggtaacctgg atctgttgca aaccaaagag
    25921 ttaccgaaag gcgtcgatcg tctggtgacg gcaatgaaca actcttccag cctgttgttg
    25981 aaaattatca gcgatattct cgatttctcg aaaattgaat cagaacagtt gaagatcgaa
    26041 ccgcgtgagt tttcaccgcg tgaagtgatg aaccacatca ccgccaacta tttaccgctg
    26101 gtggtacgca agcagttagg cttgtactgc tttattgaac cggatgtgcc agtggcctta
    26161 aatggcgacc cgatgcgttt acagcaggtc atctccaacc tgttgagtaa cgccataaaa
    26221 ttcaccgata ccggctgtat agttttgcat gttcgcgctg atggcgatta tctctctatc
    26281 cgtgttcgcg ataccggcgt ggggataccg gcgaaagaag tggtgcgctt gtttgatccc
    26341 ttcttccagg tcggaacggg cgtacagcgt aacttccagg ggactggtct gggtctggcg
    26401 atttgtgaaa aactgatcag catgatggac ggcgacatct cggtagattc agaaccggga
    26461 atgggcagcc agtttaccgt gcgtattccg ttatacggcg ctcagtaccc gcagaaaaaa
    26521 ggtgtggaag ggttgagtgg taaacgctgc tggctggcgg tccgcaatgc gtcgctctgt
    26581 cagttcctgg aaaccagttt gcagcgcagc ggcatcgtcg ttacaacata cgaagggcag
    26641 gaaccgactc ccgaagatgt gttaattact gacgaggtag tgaacaaaaa atggcagggc
    26701 agagcggtag tgaccttctg tcgtcgccat attggtattc cgctggagaa agcgccaggg
    26761 gagtgggtac atagtgtggc tgctccgcat gagctaccgg cattgttggc gcgtatttat
    26821 ttgatcgaga tggagagcga cgatcctgct aacgctctgc cgtcgacgga caaagcggtc
    26881 agcgataatg acgatatgat gattctggtc gtggatgatc atccgattaa ccggcgtctg
    26941 ctggcagatc agttgggatc gttgggctat caatgtaaaa ccgcgaatga tggcgtcgat
    27001 gcgcttaatg tacttaacaa gaatcatatt gatatcgtgc ttagcgacgt caatatgcca
    27061 aatatggatg gttaccgctt gacgcaacgc attcgtcagt tgggactgac gttgccggta
    27121 atcggagtaa ctgctaatgc gttggctgaa gagaagcagc ggtgtctgga gtccggtatg
    27181 gacagctgcc tgtcgaagcc ggtaacgctg gatgtgataa aacagacgct gacggtatat
    27241 gccgagaggg tcaggaaatc gcgggaatcg taggacggat aaggtgttta tgccgcatct
    27301 ggcattcagt gcaaatgcca gatgcgacgc tgacgcgtct tatctggcct actttaatgt
    27361 aatctgttga aataatggga atcgtaggac ggataaggtg tttacgccgc atccggcaat
    27421 ccgtgcaaat gccagataag acactgacgc gtcttatctg gcctacaggt gattagtctt
    27481 tatctgccgg actcaacgtc acagaagaga gataattcag cagagcaata tcgttctcga
    27541 cacccagctt catcatcgca gatttcttct ggctactgat ggttttaata ctgcggttca
    27601 gctttttagc gatctcggtc accaggaagc cttccgcaaa caggcgcaga acttcactct
    27661 cttttggcga gagacgcttg tcaccgtaac caccagcact gattttttcc aacaggcgag
    27721 aaacgctttc cggggtaaat ttcttccctt tctgcagcgc ggcgagagcc ttcggcaaat
    27781 cggtcggtgc accttgtttc agcacgatcc cttcgatatc cagatccaat accgcactaa
    27841 gaatcgccgg gttgttgttc atggtcagaa caatgatcga caggcttggg aaatggcgct
    27901 tgatgtactt gattaaggta atgccatcac cgtacttatc gccaggcatg gagagatcgg
    27961 taatcaacac atgcgcatcc agtttcggca gattgttgat cagtgctgta gagtcttcaa
    28021 attcgccgac aacattcacc cactcaattt gctcaagtga tttgcgaata ccgaacaaga
    28081 ctatcggatg gtcatcggca ataattacgt tcatattgtt catgtaatag gctaccttgc
    28141 tacagcaagc tcttgacata actgtcaatg tcgctgatgt atttttctat tcctggaaca
    28201 tccttctcac gaatcagatg ttccagcgtt tcacataact gcttgccggg taccagattt
    28261 agcatggcaa atacgccttt aagacgatga gccgtttggg ctaacgcagc aaagtcgctg
    28321 gttgctgctt cagtatatag cctcttaaca tcatccggta ctgtgtctac aaagagcgca
    28381 taatagccgc tggcatggag ttgcgcattt tcatctccgc ccagaggcga ttctgtcacc
    28441 tcttcctgcg ccagttgcac ttcaattaat tgtaagaccg cttcctgcat agcgttgctc
    28501 atattgaaat tgacgcacaa ttgaccaggc ccaatttccc gtacgccaga ctcatcatcg
    28561 cttaaaagca agccagaggc agtaagatta gacggattat ccgttaaaaa gatatcataa
    28621 tcttgactaa ttaatctttc atcgggtgtg atacaggttg caccccaatt ttctaactgg
    28681 cgagtgacaa tattccgaat ttctgccgaa gtaacatcca ccattacgca gacatcatcc
    28741 agtaatcgct cttcttcctc ttcaacttcc gggtcagctg cgagcatttt gatatgcaca
    28801 gagtagcgtg taccaagccc atcccgcgtt ttgatgttta aatgaccgcc cagtttacgc
    28861 gccagttgat cgctcagcca gaatgccagc gggtccgcct tgccatagcg atcgttttgg
    28921 gtctggttga taaacgggaa gtgcaaatta tccatttcat gaatgcttac gccttctcca
    28981 gtgtccagaa tgcggaacgt caggcggtct tcggaggact catcctgatc aacctcaagg
    29041 gtgatttttc ctaattgcgt tgaggtcacg gcatattgca tcagtagcag caaaatacgt
    29101 cgtaaggcat cgcgatcgcc gcggcgcata tcgtgtgctt tcagatgatt gttaatcagc
    29161 agttgcagac ctttacgctt gatggcaggc aacactgaag gcactacttc atcaattaaa
    29221 tcctgcacgg agaacagctc cgtctcactt ttccagctat cgtccgcaag catgttcgct
    29281 aactgtattt catcgaccag tcgcaccagc acatcagcct gattcgccag ttgtttgcct
    29341 tccggggcgt tgagtttagc cgcgctctcc gccagggact gtgcgggttc tttcagcgca
    29401 tcgccaatgt ttttcataaa ggtcatccgc ccctgctggt ttttctcata cagacgctgc
    29461 gcctgcttga gtttcttgtt taccagcact tcgcgatcct gatcgcgaat aatgaaaatt
    29521 tgtgtgcgcg gcgcaacctg gctgcggaac atgcggatct catacagctc gttattgatc
    29581 gtcgcctgaa taatcccctg atgctgttcc gccatggtgg tgatgttttg cagattcaaa
    29641 tgcggcagca aatgatcggc aattttgtta cttatgactg tgcggtttga ttcctgatcg
    29701 tgaaccagca ggccgagcgg cagcagtgag actatctctt cattaattgc ccgtaaaatg
    29761 cgcaattcgt tattgaccgc cgtgctgggg acgctttctg tactgcggct ggagaaatgg
    29821 cggaatgtgg tatagccaaa taacgccagc gccagcaaac cgatgttcag cagcagtggc
    29881 agcagaatgt tttgcaacgt atccagcagt aaggtgccgt aaggaacctg ccagaccagg
    29941 cgcatatcgg tagagttgag tgccgaggag atttcaatct tcgtactgtt aaagtggata
    30001 ctgacgctat ccgtcccttc tttctcattt tcattgtttc ccgttgccgt cgcgtctggc
    30061 tcaaggcgga aactgtccag cggcataccc ggtgggatca aatcattaat cggcagatca
    30121 aaagccacga ccgttgccag atgtcccggc tggttgaacg tggtacgcaa ggtaaagtaa
    30181 tgaccgttct gccaggccag gcggcgcatg ttagaaaaac tttcgcgttc atcgagggcg
    30241 ttggcctgtt gcaacatctc tgcacgacgt gaatcaacaa tgtcgctgac ggtcgattct
    30301 ttaaatccgg aggtgagatc tttgaggggc agggttgaga tcagcaccag actgttatcc
    30361 tgaccattca ggtaatacat cgaccacggt acattttctg cgccccacaa tgtgtccaga
    30421 taggtggaca tccgttgagt catctcaagc gttgagttgt cgtgagagcc aaagattaac
    30481 gcttccgttt tgcggcgtgg tttctccaga tagtagacat cctgtttcag gcgcgtctct
    30541 tgtaaacctt cgccggagga gggggaggtc gtcgcggcaa tgttgtcgta gatctgccag
    30601 gtcacgtaac gccaggtatc gacgcgcttt tggattgcgt gggtaatgtc gacaatctgg
    30661 taacttttat ctttcagcca ggcgttaacg gcgctttgta ccattacacc catcgtcacc
    30721 agtaacacaa tgatcaacag taaaaagaag cgggtaatgc tccccggtag gagtgaaaag
    30781 cgggtcgtgg ccgttgtctc tttctgacgc attcgtgttt atgacctgtt aaaacttcgc
    30841 gaagtgatag ggcagtataa agggtacagt gtgaaattcc agactcttac ctgattgatg
    30901 attctctatt ctccagtgat atttatcatc cggcattggg ggaaatagat gtacaagcgc
    30961 cattttgctg tacaaataac ctacaaaaag cccaacgaaa ttaattgcaa ataaacgaag
    31021 attgctggaa attatgctga tgttaattat ttgtgaaata gttaacaagc gttatagttt
    31081 ttctgtggta gcacagaata atgaaaagtg tgtaaagaag ggtaaaaaaa accggatgcg
    31141 aggcatccgg ttgaaatagg ggtaaacaga cattcagaaa tgaatgacgg taataaataa
    31201 agttaatgat gatagcggga gatattctag ttgcgagtga aggttttgtt ttgacattca
    31261 gtgctgtcaa atacttaaga ataagttatt gattttaacc ttgaattaat attgcttgat
    31321 gttaggtgct tattttgcca ttccgcaata atcttaaaaa gttcccttgt atttacattt
    31381 taaaacatct atagcgataa atgaaacatc ttaaaagttt tagtatcata ttcgtgttgg
    31441 attattctgc atttttgggg agaatggact tgccgactga ttaatgaggg ttaatcagta
    31501 tgcagtggca taaaaaagca aataaaggca tataacagag ggttaataac atgaaagtta
    31561 aagtactgtc cctcctggtc ccagctctgc tggtagcagg cgcagcaaac gctgctgaag
    31621 tttacaacaa agacggcaac aaattagatc tgtacggtaa agtagacggc ctgcactatt
    31681 tctctgacaa caagtcagaa gacggcgacc agacctacat gcgtcttggc ttcaaaggtg
    31741 aaactcaggt tactgaccag ctgaccggtt acggccagtg ggaatatcag atccagggca
    31801 acagcgctga aaacgaaaac aactcctgga cccgtgtggc attcgcaggt ctgtaattcc
    31861 aggatgtggg ttctttcgac tacggtcgta actacggcgt tgtttatgac gtaacttcct
    31921 ggaccgacgt actgccagaa ttcggtggcg acacttacgg ttctgacaac ttcatgcagc
    31981 agcgtggtaa cggcttcgcg acctatcgta acaccgactt cttcggtctg gttgacggcc
    32041 tgaactttgc tgttcagtac cagggtaaaa acggtagcgt agatggcgaa ggcatgacca
    32101 acaacggtcg tggtgccctg cgtcagaacg gcgacggcgt tggcggatct atcacttatg
    32161 attacgaagg cttcggtatc ggtgctgctg tttctagctc caaacgtact gatgatcaga
    32221 acttcggcct gaacggttat ggtgagcgtt atttgggtaa cggcgaccgt gctgaaacct
    32281 acactggtgg tctgaaatac gacgctaaca acatctacct ggctgctcag tatacccaga
    32341 cctacaacgc aactcgcgta ggttccttgg gttgggcaaa caaagcacag aacttcgaag
    32401 ctgttgctca gtaccagttc gacttcggtc tgcgtccgtc tgtagcctac ctgcagtcta
    32461 aaggtaaaaa cctgggtgtc atcaatggtc gtaactacga cgacgaagat atcctgaaat
    32521 atgttgatgt tggtgcgacc tactacttca acaaaaacat gtccacctac gttgactaca
    32581 aaatcaacct gctggacgac aaccgcttca cccgtgacgc tggcatcaac actgatgaca
    32641 tcgtagctct gggtctggtt taccagttct aatctcgatt gatatcgaac aaagggcctg
    32701 cgggcccttt tttcattgtt ttcagcgtac aaacacagtt ttttggtgta ctcttgcgac
    32761 cgttcgcatg aggataatca cgtatggaaa taagctttac ccgcgtggca ctgctggctg
    32821 ccgcgctctt ctttgttggt tgcgatcaaa aaccacaacc cgccaaaacc cacgctactg
    32881 aagttaccgt tcttgaaggc aaaaccatgg gtaccttctg gcgtgccagc atcccgggca
    32941 ttgacgccaa acgcagtgcc gaacttaaag aaaagattca gacccagctg gacgctgacg
    33001 atcagctgct ttcgacctat aaaaaagatt ccgcgctgat gcgctttaac gactcgcaaa
    33061 gtttgtcgcc gtggccggta agtgaagcga tggccgatat cgtcaccacc tcgctgcgca
    33121 ttggcgcaag gaccgatggt gcgatggata taaccatcgg gccgctggtg aatctgtggg
    33181 gctttggccc ggaacaacaa ccggttcaaa ttccgagcca ggaacagatc gatgcgatga
    33241 aagccaaaac cggcttacag cacctgacgg tcattaatca gtcgcatcag caatatctgc
    33301 aaaaagacct gccggattta tatgtcgatc tctccaccgt cggcgaaggt tatgcggcgg
    33361 atcacctggc acgcttgatg gagcaggaag ggatttcccg ctatctggtg tcggtgggcg
    33421 gcgcgctgaa cagccgtggt atgaacggtg caggccaacc gtggcgggta gcgattcaaa
    33481 aaccaaccga taaagaaaac gcggttcagg ccgtggtgga tatcaacggt catggtatta
    33541 gcacctctgg cagctaccgt aactattacg aactggacgg caaacgtctt tctcatgtta
    33601 tcgatccgca aaccgggcgt cctatcgaac acaatctggt atccgtgacg gtgattgccc
    33661 cgacggcgct ggaggccgat gcctgggata ctggcttgat ggtactcgga ccggagaaag
    33721 ccaaagaggt tgttcgccgg gaaggactgg cggtctacat gatcaccaaa gagggcgata
    33781 attttaaagc ctggatgtcg ccgcagttta aaagcttcct tatcagcgaa aaaaattaaa
    33841 gcgcaagatt gttggttttt gtgcgatggt gaccgggcag actaaaggct atccttaacc
    33901 agagagctga ttatgaaata cgccatacgc ttaactgacg atcaacgctg gcaatctgtc
    33961 ttagcccgcg actcgaatgc cgacggcgaa ttcgttttcg ccgtgcgcac cacgggtatc
    34021 ttttgccgtc cgtcttgccg agccagacat gccttgcggg aaaatgtctc cttctacgca
    34081 aatgccagcg aggcgcttgc cgctggcttt cgtccctgca aacgttgtca gccagacaaa
    34141 gccaatcccc tgcaacatcg ccttgataaa attacccacg cctgccgact tctggaacag
    34201 gaaacgcctg taacgctgga agccttagcc gaccaggtgg cgatgagtcc atttcatttg
    34261 catcggttgt ttaaagcgac taccggaatg acgcctaaag cctggcaaca ggcctggcgc
    34321 gctcgccgtt tgcgcgaatt gctggcgaaa ggggagagcg tgactacatc tattcttaac
    34381 gccggattcc ccgacagcag cagttactac cgcaaagccg acgaaacgct gggcatgacg
    34441 gctaaacaat tccgtcacgg tggcgaaaat ctggcggtgc gttacgcgct ggctgattgt
    34501 gagctgggcc gttgcctggt ggcagaaagt gagcggggga tttgcgcgat attactgggc
    34561 gatgatgacg cgacactaat cagcgagtta cagcagatgt ttcccgctgc cgacagcgcg
    34621 cctgctgatc tgacgtttca gcaacatgtg cgtgaagtga tcgccagcct caatcaacgc
    34681 gatacgccgc tgacgttacc gctggacatt cgcggcactg cttttcagca acaagtctgg
    34741 caggcactgc gcacgatacc ttgcggtgaa accgtcagtt atcagcaact ggctaacgcc
    34801 atcggcaaac cgaaagcggt acgggctgtt gccagcgcct gtgccgccaa caagctagct
    34861 atcgttatac cctgtcatcg ggtagtacgc ggtgatggat cgctttcagg ttaccgctgg
    34921 ggcgtgtcgc gtaaagcgca actgctacgc cgcgaagctg aaaatgagga gaggtaatgt
    34981 tggatctgtt tgccgatgct gaaccgtggc aagaaccact ggcggctgga gcggtgattt
    35041 tgcaccgttt tgcttttaac gctgcggagc aactgatccg cgatattaat gacgttgcca
    35101 gccagtcgcc gtttcgccag atggtcactc caggcggata taccatgtcg gtggcgatga
    35161 ccaactgtgg gcatctgggc tggacgaccc atcggcaagg ttatctctat tcgcccattg
    35221 atccgcaaac aaataaaccg tggcccgcca tgccgcagag ttttcatcat ttatgtcaac
    35281 gtgcggctac ggcagcgggc tatccagatt tccagccaga tgcctgtttg atcaaccgct
    35341 acgttcctgg cgcgaaactg tcgctgcatc aggataaaga cgaaccggat ctgcgcgcgc
    35401 caattgtttc tgtttctctg ggcttacccg cgatttttca atttggcggc ctgaaacgaa
    35461 atgatccgct caaacgtttg ttgttggaac atggcgatgt ggtggtatgg ggtggtgagt
    35521 cgcggctgtt ttatcatggc attcaaccgt tgaaagtggg ggggcatcca ctcaccaccg
    35581 actgccgcta caacctgaca ttccgtcagg caggtaaaaa agaataaaaa taagaattat
    35641 tattgctgtg cgcacgaaga tgtttaaact gcgggctgta attcattgtc cgggttttct
    35701 gcatggaact tcttgtactt gtctggcggc agtatcgctg gccatttatc agtgtgatgg
    35761 cgctaagcct cgccagtgcg gcattaggca ttggcttaat tgcttttatc aatcagcgcc
    35821 ttatcgaaac ggcggatacc agtctgctgg tattgccgga gtttctgggg ttattgctgc
    35881 tgttgatggc agtcactctc ggatcgcaac tggcgctcac cactttgggg catcacttcg
    35941 tttaccgact gcgtagtgaa tttatcaagc ggattctgga tacccatgtc gagcgcattg
    36001 aacaacttgg tagcgcctcg ttgctggcgg ggttaaccag cgatgtgcgc aatatcacca
    36061 ttgcttttgt gcgtctgccg gaactggtgc aggggatcat tctcactatc ggttcagcgg
    36121 cgtatttgtg gatgctgtcg ggcaaaatgt tgctggtaac ggctatctgg atggcagtca
    36181 ccatctgggg tggttttata ctggtggcgc gggtgtacaa acatatggcg accctgcgtg
    36241 aaaccgaaga taagctgtac acggattttc aaaccgtact cgaagggcgc aaagagctga
    36301 ctctgaaccg tgaacgcgcc gagtatgtgt ttaacaacct ctacattcct gatgcgcaag
    36361 agtatcgcca tcatattatc cgcgcagaca ccttccatct tagtgccgtg aactggtcaa
    36421 acatcatgat gctgggcgca atcggcctgg tgttctggat ggcgaacagt ctcggttggg
    36481 ctgataccaa cgttgccgcg acctattcgt tgacgttgtt attcctgcgt acgccgctgc
    36541 tttcggcggt tggcgcgttg ccgacgctac tgacggcgca ggtggcgttt aataagctga
    36601 acaaattcgc gctcgcgcct ttcaaagcag agtttccgcg cccgcaggcg tttcccaact
    36661 ggcaaacgct ggagctgcgt aacgtgacgt ttagctatca ggataacgcg ttttccgttg
    36721 gtccaattaa tctcaccatt aaacgtggcg agctgctgtt tctgattggt ggcaacggta
    36781 gtggaaaatc gacgctggcg atgttgctga cgggcttgta ccagccacaa aatggcgaaa
    36841 tcttgctgga tggcaaacct gtcagcggcg aacaaccgga agattatcga aaactgtttt
    36901 cggcagtgtt taccgatgtc tggctgtttg atcaactgct ggggccggag gggcaacccg
    36961 ctaacccgca actggttgag aagtggctgg cgcagctgaa aatggctcat aagcttgagt
    37021 taagcaacgg gcgtattgtt aacctgaagt tatcaaaagg gcagaaaaaa cgcgtggcgc
    37081 tgttgctggc gctggcagaa gaacgcgata ttatcctgct ggatgaatgg gcggcggatc
    37141 aggatccaca cttccgtcgt gagttttatc aggtgctgct gccgctgatg caggagatgg
    37201 gtaaaactat tttcgccatc agtcatgatg atcattactt tatccacgcc gaccgcctgc
    37261 tggaaatgcg caacgggcaa cttagcgagc tgacaggcga agagcgcgat gctgcttcgc
    37321 gtgatgccgt tgcccggaca gcataatatt acgacgctga cctggcggac tgctgccgcc
    37381 aggtcaatat tctaaaaata ccttcgtttc taataaccct ataattaatc aacgaaatta
    37441 taatgtttct aaaattagaa tataatttat aaacattatt taaatgttgt tacttaagtg
    37501 ttaccgttga tgccgcgcaa atctcacctg caataaagcg actaaaagta aggcattaac
    37561 aagatgaaaa aagtgactgc catgctcttc tcgatggccg tggggcttaa tgccgtttcg
    37621 atggcggcaa aagcgaaagc gtccgaggag caggaaactg atgtactgtt gattggcggc
    37681 ggcattatga gcgccacgtt ggggacctat ttacgcgagc tggagcctga atggtcgatg
    37741 accatggtgg agcgcctgga aggtgtcgcg caggagagtt cgaacggctg gaacaacgcc
    37801 ggaaccgggc attctgcact gatggaactc aattacaccc cgcaaaatgc cgacggcagt
    37861 atcagtattg aaaaagcagt cgccattaac gaagcatttc agatttcccg ccagttctgg
    37921 gcgcaccagg tcgagcgtgg tgtgctgcgt actccgcgtt catttatcaa taccgttccg
    37981 catatgagct ttgtctgggg cgaggataac gttaatttcc tgcgcgcccg ttacgccgcg
    38041 ttgcaacaaa gctcgctgtt tcgcggtatg cgttactctg aagatcacgc gcagatcaaa
    38101 gagtgggcac cgttagtgat ggaagggcgc gatccgcaac agaaagtagc ggcaacacgc
    38161 acagaaattg gcaccgatgt gaactatggc gagatcaccc gccagttgat cgcctcctta
    38221 cagaagaaat ctaacttctc gctgcaactc agcagcgaag tccgcgccct aaagcgtaat
    38281 gacgataaca gctggaccgt caccgttgcc gatctgaaaa acggcactgc acagaacatc
    38341 cgcgccaaat ttgtctttat cggcgcgggc ggtgcggcgc tgaaactgtt acaggaatcg
    38401 gggattccgg aggcgaaaga ctacgctggt ttcccggtgg gcggacagtt ccttgtttcg
    38461 gaaaacccgg acgtggttaa tcaccatctg gcgaaggttt acggtaaagc atccgttggc
    38521 gcaccaccga tgtcggttcc gcatatcgat acccgtgttc ttgacggtaa acgcgtagtg
    38581 ctgtttgggc catttgccac cttctcaacc aaattcctca aaaacggttc attatgggat
    38641 ctgatgagtt ccaccaccac ctctaacgtg atgccgatga tgcacgttgg gctggataat
    38701 ttcgatctgg tgaaatatct ggtgagtcag gtgatgttga gtgaagagga tcgttttgaa
    38761 gtgttgaaag agtactatcc gcaggcgaaa aaagaggact ggcgtttgtg gcaagcgggg
    38821 cagcgcgtgc agattatcaa gcgtgatgcc gataaaggtg gcgtactgcg tctcggtact
    38881 gaagtcgtca gtgaccagca agggaccatt gccgcgctcc tgggggcatc gccaggggcg
    38941 tcaaccgccg cgccgattat gttgaatctg ctggaaaaag tatttggcga tcgcgtttcc
    39001 agcccgcaat ggcaggctac gttgaaagcg atcgttccgt cttatggacg caagctgaac
    39061 ggtgatgtag cggcaacaga acgcgagttg cagtacacca gcgaagtgct gggtctgaaa
    39121 tacgacaagc cgcaggcagc agatagtacg ccgaaaccgc agttgaaacc gcaacccgtt
    39181 caaaaagaag tggcggatat tgcgttgtaa tgatgtgcca catccggcat ggtttgccgg
    39241 atgtggcgta tgctgataag acgcttcagc gtcgcatcag gcaaccggct cgggcgttag
    39301 atgtcggatg cggcgtaacc gccttattcg gcctacaggt tgcagcactt caaagcagtt
    39361 tagcgaacaa ccgcgttgtc aattttctct tccgccttcc agacacggta cttcacatcc
    39421 acattgtctg gcgtatacac cacgatcggc agcttgctgt tgtaacgcag cattccagca
    39481 tcgcccagat acgcggtgac aaatttcttc tctttcttgc catccgggca ggccatcatc
    39541 gtggaaaccg gcgagctaac tttatcaaag acataataat catagcccca gccttccagc
    39601 gttttgcttt ccagcttccc gccgagacga tgcaaattgc agtcgacttc cagcgtctga
    39661 ccgattaaca gttctacttt cagggtagat tcatcttctt gcggagttaa ctgaatcacc
    39721 tgacgcttca tgcctttttc agcttgtgga taaggcgcga ttttttccag tggctggacg
    39781 ctctctgccg cccaggcgga agtggtggcg aaagcggcaa acaatactgc aggtagaatg
    39841 gtcttcattt ttttgctttc cttcttcatt tataggtttt caccgatgat gtcgctgaag
    39901 gttaacatat tcatcagatt tattaatttg ctttatgaat aacttaaaga acattcagat
    39961 aattttacct gctcttttag tgttaaattc tgatgagaaa acaaaccagc agaaatatct
    40021 ctggcgaatt aatcgctata taa
//
LOCUS       DAPOXO010000042        40012 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPOXO010000042 DAPOXO010000000
VERSION     DAPOXO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40012
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.042"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..458)
                     /locus_tag="ROH59_002562"
     CDS             complement(<1..458)
                     /locus_tag="ROH59_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020237521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805028.1"
                     /translation="MGHGTCKAANSARHLIESKEKNRSSRVKVFSTHINLSHPAASWL
                     ATQTCANNIFNLFQNNNALYLFENDNKIELRMGHDSFFSIETIDKINKENIKGIKLKN
                     ETTYVSLPNPTILITTTSTPERQFSISVLDDDNKENLPTDTAPCFIIGIP"
     gene            complement(1028..2065)
                     /locus_tag="ROH59_002563"
     CDS             complement(1028..2065)
                     /locus_tag="ROH59_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HDX4805029.1"
                     /translation="MSDKDLTQPPAGEFIMFASGDGRVRVECRFESDTIWLSQAAMAE
                     LYDKDVRTINEHLINIFSEGELVQNSTIRKFRIVRQEGKRQVSREIDHYNLEAILAVG
                     YRVRSPRGTQFRQWATQTLQEYLIKGFVMDDERLKNPPVGSSVVPDYFDEMLERIRDI
                     RASERRVYLRVREIFALAADYQPSLKETTQFFQTIQNKLHFACTGHTAAELIHKRADA
                     SQPHMGLTSYKGEEVRKGDVTVAKNYLTQDEVSELNRVVNMWLDFAEDQARRRQQVFL
                     RDWQDKLDQFLQFNDREVLQGAGKISKKMADEKAQAEYVQFAEQQRRLKEAEGEKDIA
                     GLLQWNKESKK"
     gene            complement(2118..2212)
                     /locus_tag="ROH59_002564"
     tRNA            complement(2118..2212)
                     /locus_tag="ROH59_002564"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2176..2178),aa:Sec,seq:tca)
     gene            2505..3887
                     /locus_tag="ROH59_002565"
     CDS             2505..3887
                     /locus_tag="ROH59_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HDX4805030.1"
                     /translation="MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSMNGKMIYAAITYTLLTLLYTIVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMR
                     DDLRDIWQNDQWRIVGFLTIFNILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASITMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDA
                     AEKAQNSATISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQ
                     QQFTSQEVQN"
     gene            3897..6215
                     /gene="yicI"
                     /locus_tag="ROH59_002566"
     CDS             3897..6215
                     /gene="yicI"
                     /locus_tag="ROH59_002566"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HDX4805031.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEQQGNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYVTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHSFLSLPVYVRDSTLLALGNNDQRPDYAW
                     HEGTAFHLFNLQDGHEAVCEVPTADGSVIFTLKAARTGNTITVTGTGEAKNWTLCLRN
                     IVKVNGLQGGSQAESEQGLVVTPQGNALTITL"
     gene            6510..8063
                     /locus_tag="ROH59_002567"
     CDS             6510..8063
                     /locus_tag="ROH59_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDX4805032.1"
                     /translation="MQMITSRQNRLLRFLLPRREYTTIVTIAGYLNVSEKTIQRDLRL
                     LEQWLGQWRINVEKRAGAGVMLSAENIADLLHLDHLLVAECEEIDGVMNNARRVKIAS
                     QLLSETPNETSISKLSERYFISGASIVNDLRVIESWLAPLGLSLIRSPSGTHIEGSEG
                     QVRQAMALLINGIINHNEPQGVVYSRLDPGSYKALVHYFGEEEVLFVQSLLLDMENEL
                     SWSLGEPYYVNIFTHILIMMYRNTHGNALSREEDQTRQYDENIFNVASQMIHKIEQRI
                     AHTLPDDEVWFIYQYIISSGVAIDGQKDVSIISHMQASNEARLITWRLITVFSDIVDC
                     DFSEDSALYDGLLVHIKPLINRLNYRIHIRNPLLEDIKAELADVWRLTQYVVNQVFKT
                     WGENAVSEDEVDYLTVHFQAAMERQIARKRVLLVCSTGIGTSHLLKSRILRAFPEWTI
                     VDVISAANLSQVLPDNIELIISTINLPTVTMPVAYVTAFFNDADIKRVTEMVITEKLH
                     HATSRVVEI"
     gene            8090..8560
                     /locus_tag="ROH59_002568"
     CDS             8090..8560
                     /locus_tag="ROH59_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007370547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX4805033.1"
                     /translation="MDITKILNTNRVILDMQATNKAEAIEELTNLLKKDGAIDCRETF
                     IKDVWQREAEGSTGFENHIAIPHGKSSAVINTTLAIGRTRQDIPWETLDGSSVRCIIL
                     FAVRLEDQNTTHIRLLSQVAGALADDDIIEQLLVETSPQKIIDLFSQYAQSDVC"
     gene            8578..8892
                     /locus_tag="ROH59_002569"
     CDS             8578..8892
                     /locus_tag="ROH59_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDX4805034.1"
                     /translation="MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGT
                     ENELQAADISAADVVILAVDVKIKGEERFTNKRIVRVKTEIVIKSPVQFLEKVEKSLG
                     NK"
     gene            8917..10008
                     /locus_tag="ROH59_002570"
     CDS             8917..10008
                     /locus_tag="ROH59_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDX4805035.1"
                     /translation="MKENKITVSQEIKKHLLTGISWMIPLIVAAGICIALGQVLGGTD
                     VGEKTGTIPWMLNQIGGWGMGLIVPLISAAIAYSIADRPGFAPGLIVGFLCGQIHTGF
                     IGGMLGGFLVGYTILLLKRYIRLPQSMQGLMPIMVLPVLSTIIGGLLMMTLIGKPIAW
                     LQEALIHLLESMQGGSRFLMGAILGAMATFDFGGPVNKTMSLFSDGLLVSGVYGPEAV
                     KFVGSIIPPFGITLSFLLTRHKYTRAEREALKAAFPMGICMITEGVIPIAARDLLRVV
                     GSCVVASAVAGGLIMVWGVESPVPHGGMFVVPLFTHPLLFCLALGIGTVICGVMLSLW
                     KKPVTERDEEFDELSDQKLKDEEITFTLE"
     gene            10020..10871
                     /locus_tag="ROH59_002571"
     CDS             10020..10871
                     /locus_tag="ROH59_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HDX4805036.1"
                     /translation="MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPI
                     ILNLYQGHLAHFPAPVAAAVVKTLAESASVPVALALDHGKNPDCIRQAFRAGFSGLMI
                     DASAFPLEENVRQTRAVVELAASAQLCVEGELGHLADAPRYDQAANADLMTQPTDVEP
                     FIAQTGIDLLAVSVGTAHGMYAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQL
                     QLCTTLGVAKINVGAVIFERGKSALLHTLCHDISIELVDALKAMELAFEEAITPYLQA
                     SGAIGKA"
     gene            10952..11812
                     /locus_tag="ROH59_002572"
     CDS             10952..11812
                     /locus_tag="ROH59_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDX4805037.1"
                     /translation="MLVSMKELLQPTRQHGFAIGAFNVADNCFLRAVVDEAEATNTPA
                     IIAIHPSEHDFVGDAFFAHVREITQRSPVPFVLHLDHGASVEHVLRAIRCGFTSVMID
                     GSLLPYEENVALTAEVVRLAHAVGVSVEGELGTIGQTGTSVEGGVSQVTYTDPAQAAD
                     FIARTGADTLAVAIGTAHGIYPKGMQPKLQMDILRDIAGRIDIPLVLHGGSANPDAEI
                     AESVTLGVGKINISSDMKYAYFQKVREILAKESWWDPNVIYPDAINAAREVIRHKMKL
                     FGSLGKASLY"
     gene            11860..12792
                     /locus_tag="ROH59_002573"
     CDS             11860..12792
                     /locus_tag="ROH59_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDX4805038.1"
                     /translation="MHYLGLDIGGTKIAAVVMDAHGWEIRRYRCPTQKSTYQQFVSCV
                     VALIEQIRRDVQRPMLTGIALPGSISPLTGLIKNANIQVINGHALQADLQQLLGQPVV
                     IANDGNCFALSEACDGAGQDYDVVFGITLGTGCGGGIAIKQRPFIGAWGNAAECGHIT
                     LPGYTEQEDGPSVSCYCGKHNCVESFVSGSGFSERYQQMTGNLLTPAAIVTLAQRGDA
                     CAMQQVARFRQQLARTLATIVNVVDPGVIVIGGGLSNVELLITDLNAEVAPLVFTDQF
                     TTPIVKAQHGDSSGMRGAAWLAMRNGEANETFTN"
     gene            12773..13453
                     /locus_tag="ROH59_002574"
     CDS             12773..13453
                     /locus_tag="ROH59_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HDX4805039.1"
                     /translation="MKRSQINYVIDKAHAIAQTFRVCLPEFAYFTVDDWLQRERDNWQ
                     EVVDLQLGWDITDFGRGDFNQTGLTLLTMRNGALGSAAYPKPYAEKMLQIQQDQQTPW
                     HFHTHKMEDILNRGGGDLCMQLAWANEANLCDDQRVITVSVDGQRRTMKPGETLVLKP
                     GQGICLPPRLYHRFWAEKAFVLGWEISMVNDDQHDNYFLEPGGRFPAIEEDEPVKWLL
                     CGEYGILR"
     gene            complement(13497..15206)
                     /locus_tag="ROH59_002575"
     CDS             complement(13497..15206)
                     /locus_tag="ROH59_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDX4805040.1"
                     /translation="MKFIGKLLLYILIALLVVIAGLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLKNVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPEAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRMADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVADLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFAPQGVALRQFTSRWEGG
                     MVRTSGNWQRDGKTLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNSLQLKRFSASRN
                     LIIDIDPDFPWQLTALDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQHWGWPEL
                     PLTGDGNIQLTASGDIQVNVPLKPTVSGQLHAVNAAKQQVTQTMNAGVVSSGEVTSTE
                     PVQ"
     gene            complement(15327..16718)
                     /gene="xanP"
                     /locus_tag="ROH59_002576"
     CDS             complement(15327..16718)
                     /gene="xanP"
                     /locus_tag="ROH59_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HDX4805041.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            16998..18203
                     /gene="gltS"
                     /locus_tag="ROH59_002577"
     CDS             16998..18203
                     /gene="gltS"
                     /locus_tag="ROH59_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDX4805042.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLILKKSMGWEVNFDMSLRDPLMLAFFATIGLNANLASLRAGGRVVGVFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSMMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            complement(18237..20318)
                     /gene="recG"
                     /locus_tag="ROH59_002578"
     CDS             complement(18237..20318)
                     /gene="recG"
                     /locus_tag="ROH59_002578"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDX4805043.1"
                     /translation="MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFNAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARV
                     VAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIEVGWLAGKQKGKARLAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVRHACMTEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPAEKQAVMTSFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(20324..21013)
                     /gene="trmH"
                     /locus_tag="ROH59_002579"
     CDS             complement(20324..21013)
                     /gene="trmH"
                     /locus_tag="ROH59_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HDX4805044.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWSTMQAAG"
     gene            complement(21020..23128)
                     /gene="spoT"
                     /locus_tag="ROH59_002580"
     CDS             complement(21020..23128)
                     /gene="spoT"
                     /locus_tag="ROH59_002580"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HDX4805045.1"
                     /translation="MYLFESLNQLIQNYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            complement(23147..23422)
                     /gene="rpoZ"
                     /locus_tag="ROH59_002581"
     CDS             complement(23147..23422)
                     /gene="rpoZ"
                     /locus_tag="ROH59_002581"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDX4805046.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            complement(23477..24100)
                     /gene="gmk"
                     /locus_tag="ROH59_002582"
     CDS             complement(23477..24100)
                     /gene="gmk"
                     /locus_tag="ROH59_002582"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDX4805047.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            24358..26040
                     /gene="ligB"
                     /locus_tag="ROH59_002583"
     CDS             24358..26040
                     /gene="ligB"
                     /locus_tag="ROH59_002583"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709426.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HDX4805048.1"
                     /translation="MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGNETRDVMIPPLNGAVMHPVAHTGVRK
                     MADKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVRL
                     ISAVPQTVSGPLANSTLQGEIFLKRKGHIQQQMGGINARAKVAGLMMRQGNSDTLNSL
                     AVFVWAWPDGPHLMTDRLKDLATAGFTLTQTYTRAVKNADEVAHVRNEWWKAKLPFVT
                     DGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLV
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHQFNLARQQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP"
     gene            complement(26037..26654)
                     /locus_tag="ROH59_002584"
     CDS             complement(26037..26654)
                     /locus_tag="ROH59_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HDX4805049.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(26906..27769)
                     /locus_tag="ROH59_002585"
     CDS             complement(26906..27769)
                     /locus_tag="ROH59_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDX4805050.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIIARETEGQALKVLIEQRL
                     EGVTAEVVKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            27896..28612
                     /gene="rph"
                     /locus_tag="ROH59_002586"
     CDS             27896..28612
                     /gene="rph"
                     /locus_tag="ROH59_002586"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDX4805051.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            28678..29319
                     /gene="pyrE"
                     /locus_tag="ROH59_002587"
     CDS             28678..29319
                     /gene="pyrE"
                     /locus_tag="ROH59_002587"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDX4805052.1"
                     /translation="MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV"
     gene            complement(29356..29952)
                     /gene="slmA"
                     /locus_tag="ROH59_002588"
     CDS             complement(29356..29952)
                     /gene="slmA"
                     /locus_tag="ROH59_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HDX4805053.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(30059..30517)
                     /gene="dut"
                     /locus_tag="ROH59_002589"
     CDS             complement(30059..30517)
                     /gene="dut"
                     /locus_tag="ROH59_002589"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDX4805054.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            complement(30495..31715)
                     /gene="coaBC"
                     /locus_tag="ROH59_002590"
     CDS             complement(30495..31715)
                     /gene="coaBC"
                     /locus_tag="ROH59_002590"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDX4805055.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVCVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVNRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            31887..32555
                     /gene="radC"
                     /locus_tag="ROH59_002591"
     CDS             31887..32555
                     /gene="radC"
                     /locus_tag="ROH59_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709417.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDX4805056.1"
                     /translation="MKNNVQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            32772..33008
                     /gene="rpmB"
                     /locus_tag="ROH59_002592"
     CDS             32772..33008
                     /gene="rpmB"
                     /locus_tag="ROH59_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDX4805057.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            33029..33196
                     /gene="rpmG"
                     /locus_tag="ROH59_002593"
     CDS             33029..33196
                     /gene="rpmG"
                     /locus_tag="ROH59_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDX4805058.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            33294..34103
                     /gene="mutM"
                     /locus_tag="ROH59_002594"
     CDS             33294..34103
                     /gene="mutM"
                     /locus_tag="ROH59_002594"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HDX4805059.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(34142..34621)
                     /gene="coaD"
                     /locus_tag="ROH59_002595"
     CDS             complement(34142..34621)
                     /gene="coaD"
                     /locus_tag="ROH59_002595"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDX4805060.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRASQMFDHVILAIAASPSKKP
                     MFTLEERVELAQQATAHLENVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(34629..35906)
                     /gene="waaA"
                     /locus_tag="ROH59_002596"
     CDS             complement(34629..35906)
                     /gene="waaA"
                     /locus_tag="ROH59_002596"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HDX4805061.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            36320..37378
                     /gene="rfaQ"
                     /locus_tag="ROH59_002597"
     CDS             36320..37378
                     /gene="rfaQ"
                     /locus_tag="ROH59_002597"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HDX4805062.1"
                     /translation="MDKPFRRILLIKMRFHGDMLLTTPVISSLKKNYPDAKIDVLLYQ
                     DTIPILSENPEINALYGIKNKKAKASEKIANFFHLIKVLRANKYDLIVNLTDQWMVAI
                     LVRLLNARVKISQDYHHRQSAFWRNSFTHLVPLQGGNVVESNLSVLTPLGLESLVKQT
                     TMSYPPANWKRMRRELDHAGVGQNYVVIQPTARQIFKCWDNAKFSAVIDALHARGYEV
                     VLTSGPDKDDLACVNEIAQGCQTPPVTALAGKVTFPELGALIDHAQLFIGVDSAPAHI
                     AAAVNTPLISLFGATDHIFWRPWSNNMIQFWAGDYREMPTRDQRDRNEMYLSVIPAAD
                     VIAAVDKLLPSSTTGTSL"
     gene            37375..38499
                     /locus_tag="ROH59_002598"
     CDS             37375..38499
                     /locus_tag="ROH59_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDX4805063.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIAQTVAARGHHVRVYTQSWEGE
                     CPDVFELIKVPVKSHTNHGRNAEYFAWVQKHLREHPVDRVVGFNKMPGLDVYYAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEQGKPTQLLMLTDKQIADFQKHYQTEAE
                     RFHILPPGIYPDRKYSQQPANSREIFRKKNGITEQQYLLLQVGSDFTRKGVDRSIEAL
                     ASLPDSLRHNTLLYVVGQDKPRKFEALAEKRGVRSNVHFFSGRNDVSELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAIAEPFRQETLNEILRKA
                     LTQSSLRQAWAENARHYADTQDLYSLPEKAADIITGGLDG"
     gene            38492..39289
                     /gene="rfaP"
                     /locus_tag="ROH59_002599"
     CDS             38492..39289
                     /gene="rfaP"
                     /locus_tag="ROH59_002599"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312532.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HDX4805064.1"
                     /translation="MVELKEPFATLWRGKDPFEEVKTLQGEVFRELETRRTLRFEMAG
                     KSYFLKWHRGTTLKEIIKNLLSLRMPVLGADREWNAIHRLRDVGVDTMYGVAFGEKGI
                     NPLTRTSFIITEDLTPTISLEDYCADWATNPPDVRVKRMLIKRVATMVRDMHAAGINH
                     RDCYICHFLLHLPFSGKEEELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFGMPLRKILSFERNLLNMASVKAEHIKERTQRKGL"
     gene            39326..>40012
                     /locus_tag="ROH59_002600"
     CDS             39326..>40012
                     /locus_tag="ROH59_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDX4805065.1"
                     /translation="MTIYFINWVADYELKMIQYLKKKHKIKNITTPKKYNWVNKKISK
                     LGMDNAWLGRLFIKHHLNAVKKDDIIIFNDSVINKSINKQILKNINCHKVLLLRNTVS
                     ENFIFDNANYFDIIYDFEHRFIGNEKIKAIEQFFPIGMDEIRNYSLSDKNNSQPICFF
                     LGRDKGRLQIINELADRLTTLGCKLDFNVVKDKTSSPTSKYLIEKQISYEENIRRTLN
                     ANIIVDITKEN"
BASE COUNT         9742 a         9586 c        10542 g        10142 t
ORIGIN      
        1 tcaggaatac caattataaa acaaggtgcg gtatcggtag gtagattttc tttgttatca
       61 tcatccagaa cagaaataga aaactgtcgt tcaggtgttg atgttgtggt tattaaaatg
      121 gttggattag gaagagaaac atatgttgtc tcatttttta gttttattcc tttgatgttt
      181 tctttgttaa ttttatcaat cgtttcaata gagaaaaaag aatcatgccc cattcgcagt
      241 tcaattttat tatcgttttc gaataaataa agggcattat tgttttgaaa cagattgaat
      301 atattgttag cgcaagtttg agttgctagc caggatgccg ctggatgact caaattaata
      361 tgtgtgctaa agactttgac gcgactactt ctgtttttct ctttactttc aattaaatgc
      421 ctagcgctgt tggctgcttt acaagttcca tgccccacac ggcaaaaata atctcctgaa
      481 aggatactta caatcagtat tacaccaatg acgacagaaa aaatagttcc gatgagtttg
      541 atgatgacaa tccttgtgca gtgttatttt caccatggat tataatgtta tagtgaaatt
      601 attgcacctg taatttttct ttgattgttt taatcatcac atttacgcac ttcttcatct
      661 ttgtagcagg taaaagccat atatggatgg ctggtgtccg gtgcagataa aatgcaactt
      721 attcttgata gcttgaaaaa agagaggttt ttttgagtga cggttgatgg tcggtggcaa
      781 ggaagacgtt ttcgtacact cggcaagaaa aatgaatcac tctgtcatac taccagatac
      841 atcagcaggg tcaggttgct cagaaataag caggatgggg atcactgaag aggcattttg
      901 gcgatcacag gagtcgcatt tgatggttaa gttattgatt taatgtttat attttgaact
      961 tgataaatga gtaaccccat aagtaccccc aaatggtttt gcgtatggcg tttgggggga
     1021 ttccgggcta ctttttcgac tctttattcc actgtagcaa accagcgata tccttctcgc
     1081 cttcggcttc ttttaagcgc cgttgttgtt cggcaaactg aacatactcc gcctgcgctt
     1141 tttcatcggc cattttcttg ctgattttac cagcgccctg tagaacctct cggtcgttaa
     1201 attgcaggaa ctgatccagc ttatcctgcc agtcgcgcaa aaagacttgc tgacgacgac
     1261 gggcctgatc ctcggcaaag tccagccaca tattaaccac gcgattaagt tcgctgacct
     1321 catcctgggt gagataattt tttgccaccg tcacgtcgcc cttacgtacc tcttcacctt
     1381 tataactggt caagcccatg tgcggctggc tggcatctgc tcgtttgtgg atgagttccg
     1441 cagcggtatg cccggtacag gcaaaatgca gtttattctg gatggtttga aaaaattgcg
     1501 tggtttcttt aagcgatggc tgatagtcgg cagctaaagc aaagatctcc cgcacccgca
     1561 aatatacccg acgctcgctg gcgcgaatat cgcggatgcg ttcaagcatc tcatcaaaat
     1621 agtcgggcac aaccgatgaa ccgacaggcg gattcttcag ccgctcatcg tccatcacaa
     1681 aacctttgat caggtattcc tgaagcgtct gggtggccca ctggcggaat tgcgtgcctc
     1741 gaggcgagcg aacgcgatag ccgacagcga gaatggcttc gaggttgtaa tggtctatct
     1801 ctctggaaac ctgacgtttt ccttcctggc gaactatccg gaatttccgg atggttgagt
     1861 tttgaacaag ttcaccttcg gaaaatatat tgattaaatg ttcgttaata gtgcgaacat
     1921 ctttatcgta cagttcagcc attgccgcct gggataacca gattgtgtct gactcaaagc
     1981 gacattcaac acgcactctt ccgtcaccgc tggcaaacat aataaactcg cctgctgggg
     2041 gctgggttaa gtctttgtct gacatgttgc ctccgaagga gtgttgttga cgtcgggaga
     2101 gttcaggaga ggcattttgg cggaagatca caggagtcga acctgcccgg gaccgctggc
     2161 ggccccaact ggatttgaag tccagccgcc tcaccggaga cgacgatctt ccgcgcctcg
     2221 attgctacat ggaggcgggg cgcattatag ctacttcctt gagtttctac atcccccaga
     2281 tcagtttttt ccgcctaata cacgcagcgt attatcacga aagcattata gttcatataa
     2341 aactcatatt ttacaatgat atatgagcga aattaacgct accacgatca cataaaacaa
     2401 gaatcataaa ttaataacca gatatcggaa tattcgctct cgcagggatg gtttacaaaa
     2461 tgcgttatcg gtctcagcac ccctatagca tcaaggaaaa gcagatgaag agtgaagtgt
     2521 tgtccgttaa agagaaaatt ggttatggca tgggagacgc cgccagccac attattttcg
     2581 ataacgtaat gttatatatg atgttctttt ataccgatat ttttggcatt cctgccggat
     2641 ttgtcggaac catgtttttg gtcgctcgtg cactggatgc gatttccgat ccttgcatgg
     2701 gattgttggc cgatcgaacg cgctctcgct ggggtaaatt tcggccgtgg gtactgtttg
     2761 gtgcactgcc attcgggatc gtctgtgtac tagcctatag cacgccagat ctcagtatga
     2821 acggaaaaat gatttatgca gcaattactt acaccctact taccttactt tataccatcg
     2881 tcaatatccc ttactgcgca ttgggtggtg taatcaccaa tgacccgact cagcgtatct
     2941 cgctgcaatc ctggcgtttt gtgctggcga ccgcgggagg catgctctct actgttctga
     3001 tgatgccact ggttaattta attggtggtg ataataaacc actcggtttc cagggcggta
     3061 tcgcggtcct ttccgtggtg gcatttatga tgctggcatt ctgtttcttc accactaaag
     3121 aacgcgttga agcaccacct acaacgacgt ctatgcggga tgatttacgt gatatctggc
     3181 aaaacgacca gtggcgtatt gtcggtttcc tgaccatttt caatatcctg gcggtgtgcg
     3241 tacgtggtgg ggcgatgatg tattacgtca catggatttt gggtacgccg gaagtatttg
     3301 ttgcttttct caccacttat tgcgtgggta acctgattgg ttccgcactg gcaaaaccgc
     3361 tgaccgactg gaaatgtaaa gtcactatct tctggtggac gaacgccctg ctggcagtga
     3421 ttagcctcgc gatgttcttt gttcctatgc aggccagcat caccatgttt gtcttcatct
     3481 tcgtgattgg tgtgttgcat caactggtga cacctatcca gtgggtaatg atgtccgata
     3541 ccgtcgacta cggcgagtgg tgtaatggta aacgcctgac cgggatcagt tttgctggca
     3601 cgctgtttgt gctcaaactg gggttggcct tcggtggtgc ccttatcggc tggatgctgg
     3661 cttatggcgg atatgatgcg gcagaaaaag cgcagaacag cgccacaatt agcatcatta
     3721 tcgcgctatt cacgattgtt ccggcgatct gttacttgct gagcgcgatt atcgctaaac
     3781 gctactactc gctcacgacg cacaatctga aaaccgttat ggaacagctg gcgcagggca
     3841 aacgccgttg ccagcaacaa ttcacctctc aagaagtgca gaactaagga acggcaatga
     3901 aaattagcga cggaaactgg ttgattcaac ctggcctcaa tttgattcac ccgcttcagg
     3961 tgttcgaggt tgaacagcag ggtaatgaaa tggtggtcta tgctgcccct cgtgatgtgc
     4021 gtgaacgtac ctggcagctt gatacgcctt tatttacgct gcgctttttc tccccacagg
     4081 aaggtattgt cggtgtacgg attgagcatt ttcagggggc gctgaataac ggtcctcatt
     4141 acccgctcaa tattttgcag gacgtgaagg tcactatcga aaacacagaa cgttacgctg
     4201 agtttaaaag tggcaactta agtgcgcgtg tcagcaaagg tgagttctgg tcactggatt
     4261 ttctgcgcaa cggcgaacgt attaccggta gtcaggtgaa aaataatggc tacgtgcagg
     4321 acacgaataa tcaacgaaat tatatgtttg aacggctgga tcttggcgtt ggcgaaacag
     4381 tttacggcct gggagagcgc tttactgccc tggtgcgcaa tggtcagacg gtagaaacct
     4441 ggaaccggga cggcggcaca agtactgaac aggcgtataa aaatatcccg ttttatgtga
     4501 ctaaccgtgg ttatggggta ctggtcaatc atccccaatg tgtctctttt gaagtgggat
     4561 cggagaaagt ctccaaagta cagttcagcg ttgagagtga atatctcgaa tactttgtta
     4621 tcgacggccc gacgcctaaa gcggtacttg atcgttatac ccgttttact ggccgtccgg
     4681 cgctgccgcc cgcgtggtcc ttcggtctgt ggctaaccac ttcatttacc accaactacg
     4741 acgaagcgac ggtaaacagc tttatcgatg gtatggcgga acgcaatctg ccgctgcatg
     4801 ttttccactt tgactgtttc tggatgaaag ccttccagtg gtgcgatttt gagtgggatc
     4861 cgctgacttt tccggacccg gaagggatga tccgccgcct gaaagcgaaa gggctgaaaa
     4921 tctgcgtctg gattaacccc tatattgggc aaaaatcccc cgtctttaaa gagttacaag
     4981 agaaaggtta tttactcaaa cgcccggacg gttcgctgtg gcagtgggat aaatggcagc
     5041 caggtctggc gatttatgac tttaccaatc cggatgcctg caaatggtac gccgacaaac
     5101 tgaaaggtct ggtcgcgatg ggcgttgatt gctttaagac cgactttggc gaacgtattc
     5161 caaccgatgt tcaatggttt gatggttccg atccgcagaa aatgcataac cattatgcat
     5221 acatctacaa cgaactggtg tggaacgtgc tcaaggacac cgttggtgag gaagaagccg
     5281 tcttgtttgc ccgctcggcc tccgttggtg cgcagaaatt tccggtacac tggggtggcg
     5341 actgttacgc taactacgaa tcaatggcgg aaagcctgcg cggtggtttg tctattggcc
     5401 tttcaggttt tggcttctgg agccacgata tcggcggctt tgaaaatacc gctccggcgc
     5461 acgtttacaa acgctggtgc gcgtttggtt tgctctccag ccatagccgt ttacatggca
     5521 gcaaatctta tcgtgtgccg tgggcctacg atgatgagtc ctgtgatgtg gtgcgcttct
     5581 tcacgcaact gaaatgccgc atgatgccgt atctgtatcg tgaagctgca cgtgcaaacg
     5641 cccggggtac gccgatgatg cgggccatga tgatggagtt cccggacgat ccggcttgtg
     5701 attaccttga ccgtcaatac atgttaggcg acaacgtgat ggttgcgcct gtgttcactg
     5761 aagcgggcga tgtgcagttc tacctgccgg aaggtcgctg gacacacctg tggcacaacg
     5821 atgaactcga cggtagtcgc tggcataaac agcagcacag cttcctgagt ctgcccgttt
     5881 atgtgcgtga tagcacccta ctggcgctgg gcaacaacga tcaacgtccc gattacgcgt
     5941 ggcacgaagg tacggcattc cacctcttta atctgcaaga cgggcatgaa gccgtctgtg
     6001 aagtgcccac tgctgacggt tcggtgatct ttactttaaa agcagcacgt actggcaaca
     6061 cgattactgt gactggtacg ggcgaggcga agaactggac actgtgcttg cgcaatattg
     6121 tgaaagtaaa tggtctgcaa ggcggttcgc aggctgaaag tgagcaggga ctggtggtga
     6181 ctcctcaagg gaatgcgctg acaattacgt tgtaatctat tgaagaatgc cggatacgaa
     6241 tggttttgtg tcgtatccgg taaataatct cacatctggt aataaatatt tcttccatcg
     6301 tatttgcgag catgatcacg attattcatc acgaaaatgt gatctgtgct gaaaaatatc
     6361 ccttaaccgc cttgctttgt tttatcactg tccggattac ggacagattt tagtattgtt
     6421 gtgaaattat tctgctttat atttaccctc agagatggca actgaagctc ttccatatgg
     6481 ggcttcttaa tctgtgataa gggtaaaaaa tgcaaatgat tacctcgcga caaaacagat
     6541 tattacgatt ccttttacct cgaagggaat atacgactat tgttacgatt gccggctatt
     6601 taaatgtttc ggaaaaaacc attcaacgtg atttacgttt acttgagcaa tggctgggac
     6661 aatggagaat aaatgttgag aagcgtgctg gcgcgggtgt gatgttaagc gcggagaata
     6721 ttgctgattt gctgcatctt gatcatttgt tggtggcaga atgtgaagag attgatggtg
     6781 taatgaataa tgccaggcgc gttaaaatag cgtcgcagtt attaagtgaa acaccgaatg
     6841 aaacgtcgat cagtaaattg tcagaacgct attttatcag cggagcctct attgttaatg
     6901 acctgagagt aattgagtcc tggcttgcgc cgttggggtt atcgttgatc cgcagcccaa
     6961 gtggtacgca tattgaaggt agtgaagggc aagtccgaca ggcaatggca ttactgatta
     7021 acggcattat taaccataat gagccgcaag gtgtcgtgta ttcacgtctg gatcccggaa
     7081 gctataaagc attagtccat tattttggag aggaagaagt gttatttgtc cagtcattgt
     7141 tactggatat ggaaaatgaa ttaagttggt ctttgggaga accttattac gttaacattt
     7201 ttactcatat ccttattatg atgtatcgca acacgcacgg gaatgcgtta tcaagagaag
     7261 aagatcaaac caggcaatat gatgaaaata tctttaatgt tgccagtcag atgattcata
     7321 agatagaaca acgaattgca catacattgc ccgatgatga agtctggttt atttatcaat
     7381 atatcatttc atcaggtgtg gcgattgatg gacaaaaaga tgttagcatt atttcacata
     7441 tgcaggccag caatgaagcg cgtctgatta cctggcgttt aattacggta ttcagtgaca
     7501 tcgtggactg cgattttagt gaagacagcg cattatatga tggcttattg gtgcatatta
     7561 aaccgctgat taaccgacta aattatcgta ttcatatccg taatccattg ctggaagata
     7621 ttaaagcaga attagcggat gtctggcggt tgacgcaata tgtggtgaat caggtattta
     7681 aaacctgggg tgagaatgcg gtgagcgagg atgaagtgga ttacctgacc gttcattttc
     7741 aggctgcgat ggaacggcaa attgcccgta aacgcgtatt actggtctgt tcaaccggaa
     7801 tcggaacttc gcatctactg aaaagccgta ttctgcgagc atttcctgaa tggacgattg
     7861 ttgatgttat ttcagcagcg aatttatcac aggttttgcc tgacaatatc gaactgatta
     7921 tttcgaccat taatttgcct acagtcacta tgccggtcgc ttatgttacc gcttttttta
     7981 atgatgccga tattaagcgg gtcactgaaa tggtgattac ggaaaaatta catcatgcga
     8041 cgtctcgggt cgttgaaatt taatgtcaga attttatgag gtatgacgaa tggacataac
     8101 aaaaatcctg aatacgaatc gcgttatttt agatatgcaa gcgacgaata aagcggaggc
     8161 gattgaagaa ttaactaatc ttctcaaaaa agatggtgcg atcgattgtc gggaaacctt
     8221 tattaaagat gtctggcagc gcgaagcgga aggctcgact ggttttgaaa atcatattgc
     8281 gatcccgcat ggtaaatctt cagctgtgat taatactacg ctggcaattg gccgtacccg
     8341 ccaggatatt ccctgggaaa cgctggatgg cagtagcgtg cgctgtatta ttttatttgc
     8401 ggtacgtctt gaagatcaaa ataccaccca tatccgttta ctttcccagg tcgcgggcgc
     8461 gctggcggat gatgacatca tagaacaatt gttagttgag acgagtccgc aaaaaatcat
     8521 tgatctcttt agtcagtatg cacaatccga tgtctgctaa ataacaggga gtatgtcatg
     8581 aatattgtct gtgttgccgc ctgtacggcg ggtattgctc atacctatat tgctcgtgaa
     8641 aagttaatca aaggagcaaa agctctgggc cataccatta aagttgaaac ccagggaacc
     8701 attggtacag aaaatgaatt acaggcggca gatatctctg ctgctgacgt cgtgattctt
     8761 gctgtagatg tgaaaataaa aggagaagaa cgcttcacca ataaacgtat tgtgcgagta
     8821 aagacagaga tcgtcattaa gtcgcccgtt caatttcttg aaaaggtcga aaaatcactg
     8881 ggaaacaaat gatccttata ctggagggat cttaatatga aagaaaataa aattacggtt
     8941 tcacaggaaa ttaaaaaaca tttattaacc ggcatctcgt ggatgatacc ccttattgtg
     9001 gccgccggga tatgtattgc gttggggcaa gttcttggcg gtacagatgt tggtgaaaaa
     9061 acaggaacaa tcccgtggat gcttaatcag attggcggct ggggaatggg gctgattgtg
     9121 ccgctgatta gcgcggcaat tgcctattct attgccgatc gtcccggatt tgccccgggc
     9181 ctgattgtcg gctttctctg tgggcaaatc cataccggat ttattggcgg tatgttgggt
     9241 ggtttcctgg tgggctacac cattttgcta cttaaacgct atatccgcct gccgcagtcg
     9301 atgcaaggac tcatgccaat catggtgttg ccggtattaa gcaccattat cggtgggctg
     9361 ttaatgatga cgctgattgg taaacccatc gcctggttac aagaagcact gattcatttg
     9421 ctcgagtcga tgcagggcgg atcgcgcttc ctgatggggg ccatacttgg cgcgatggca
     9481 accttcgatt tcggtggtcc ggtcaacaaa accatgtcgc tgttttccga tggcttgctg
     9541 gtcagtggcg tctacggacc agaagccgtg aaatttgtcg gctcaatcat ccctccgttt
     9601 ggcatcacac tttcgttctt actgacacgc cataaataca cccgtgcgga gcgcgaggcg
     9661 ctgaaagccg cgtttccgat ggggatctgc atgattactg aaggagtcat tccgatcgcc
     9721 gcgcgtgacc tactgcgagt agtgggatct tgtgtggtgg catcggcggt cgcgggcggc
     9781 ttaatcatgg tgtggggcgt ggagagtccg gttccgcatg gcggcatgtt tgttgtgcct
     9841 ctgttcaccc atcctctgct gttttgcctg gcgctgggta taggcacggt gatttgtggc
     9901 gtgatgcttt cactctggaa gaaaccggta acggaacgcg acgaagagtt tgacgaactg
     9961 agcgatcaaa agctgaaaga tgaagagatc actttcaccc tcgaataacc ggaggcccta
    10021 tgtttgccga tatgaaaagt atggtgatga aagcctggca tgaacattac gccttgctgg
    10081 cgatcaactg tatgaatctg gaaagtgctc acgcagctat ccgcgtggcg gagaagaatc
    10141 gcgctccgat cattctcaat ctctatcagg ggcatctggc gcattttcct gcacccgtcg
    10201 cggcggcagt ggttaaaacg ctcgcggaat ctgcctcagt accggtcgct ctggcgcttg
    10261 atcatggcaa aaatccggac tgtattcgtc aggcgtttcg tgctggtttc agcggattaa
    10321 tgattgatgc ttctgctttt cccctggagg aaaacgtgcg ccagaccagg gcggtggtgg
    10381 aactcgccgc cagcgcgcag ctctgcgtgg aaggcgaact gggccatctg gcagatgcgc
    10441 cgcgttacga ccaggccgcc aatgcagacc tgatgacgca acccactgat gtggaaccgt
    10501 ttatcgcgca gacaggcatt gatctactgg ccgtctcggt aggcacggcg cacggcatgt
    10561 acgcgcctgg cgttgtacct gctattgatt ttcagcgtct ggcggagatt ttccactgct
    10621 cgagcgtgcc tctggcatta catggcggta gcggtacgcc gttcgatcag ctccagctct
    10681 gtacgactct gggggtagca aaaatcaacg tgggggcggt catttttgaa cgggggaaat
    10741 ccgcgctcct gcataccctc tgtcacgata tatccattga actggtggac gcgctgaaag
    10801 ctatggaact ggccttcgaa gaagcgatta caccgtattt acaggcgagc ggcgctatcg
    10861 gcaaagcctg attcattttc tgtcatggcc tttatgccag tgcaataacg caccggcagg
    10921 gcggactaca cgctgaaact ggagatttaa catgttagtt tcgatgaaag aattactgca
    10981 acctacccgc cagcacggct ttgccattgg cgcatttaat gtggcggata actgtttcct
    11041 tcgcgcagtc gtggatgaag cagaagcgac aaatactccg gcgattattg ccatccatcc
    11101 cagcgaacat gattttgtgg gcgatgcctt tttcgctcac gttcgcgaaa ttacccagcg
    11161 tagtccggtc ccgtttgtac tgcacctcga tcatggtgcc tctgtagagc atgttttgcg
    11221 tgcgattcgc tgcggattta cctcagtaat gatcgacggt tcgctgctgc cgtatgaaga
    11281 aaacgtggcg ctgaccgcag aagtggttcg cctcgctcac gcggttggcg tgtcggttga
    11341 gggtgaactg ggaaccatcg gacaaacagg aacgtcggta gaaggtggtg tttcacaagt
    11401 gacctacaca gatccggcgc aggccgccga ttttattgct cgtacaggtg ccgacacact
    11461 ggctgtggcg attggtacag cgcatggcat ctatccaaaa gggatgcagc cgaagctgca
    11521 aatggacatt ttgcgcgaca ttgccggacg tattgatatt ccgctggtgc tacacggtgg
    11581 ttcggcaaac ccggacgcgg agattgctga atcagttacg ctcggcgtcg gcaaaatcaa
    11641 tatctccagc gatatgaaat acgcctattt ccagaaagtg cgtgaaattc tcgctaaaga
    11701 gagctggtgg gacccgaacg tcatctatcc ggatgcgatt aacgcggcgc gggaagtcat
    11761 tcgccacaaa atgaaactgt tcggttcgct cggtaaagca tcactgtact aagccagaag
    11821 ggcggggtga cccgcctttt acgcaacaag gaacgagata tgcactatct ggggttggat
    11881 attggtggga ccaaaatcgc cgccgttgtc atggatgcgc atggctggga gattcgccgt
    11941 taccgctgcc cgacgcaaaa gtcgacatat caacaatttg tctcatgcgt tgtggcgctt
    12001 atcgagcaga ttaggcggga cgttcaacga ccgatgctga cagggatcgc cttacccggc
    12061 agtatctcgc cactcactgg cctgattaaa aacgcgaata ttcaggtgat taacggtcat
    12121 gcgttacagg ctgatttgca gcaattgctt gggcaaccgg tggtgatagc caatgatggt
    12181 aactgtttcg cgctatcaga agcttgcgac ggtgccgggc aagattatga cgtggtattt
    12241 ggtattacgc ttggtacggg ctgcggcggt ggcattgcca tcaagcaacg accgtttata
    12301 ggggcctggg gaaatgctgc cgaatgcggt catatcacgt tgccaggcta tacggagcag
    12361 gaagatggtc catcagtcag ttgctattgc ggcaaacaca actgcgtgga gtcgtttgtt
    12421 tccggcagcg gttttagtga acgctatcaa cagatgactg gtaacttgct cactcctgcg
    12481 gcgattgtca ccctggcaca acgtggtgat gcttgtgcca tgcagcaggt ggcacgtttt
    12541 cgccaacagc ttgcccgcac gctggcaacc atcgttaacg ttgttgaccc tggcgtgatt
    12601 gtgatcggcg gcgggctttc gaatgtggaa ctgcttatca ccgatctgaa cgcagaagtc
    12661 gctccactgg ttttcaccga tcaattcacc actcccattg taaaagcaca gcacggcgac
    12721 agtagcggaa tgcgtggcgc tgcctggctt gctatgcgca acggagaagc caatgaaacg
    12781 ttcacaaatt aattatgtta ttgataaagc acatgccatt gcgcagacct tccgcgtttg
    12841 tttgccagag ttcgcctatt ttacggtgga tgactggctg cagcgggaac gggataactg
    12901 gcaagaagtg gtcgacttac agctcggttg ggatatcacc gattttggtc gtggtgattt
    12961 caaccaaacg ggactaacac tgctaacgat gcgcaacggc gcgctggggt cggcggcata
    13021 tccaaaaccg tatgctgaga aaatgttgca gatccaacaa gatcagcaga ctccctggca
    13081 ttttcacacc cacaaaatgg aagatatcct caatcggggc ggtggagact tatgcatgca
    13141 gttggcctgg gccaacgaag ccaatctctg tgatgatcaa cgagtcatta ccgtgagtgt
    13201 tgatggtcag cggcgtacca tgaaacctgg tgaaacgctg gtgctaaagc cggggcaggg
    13261 catttgcctg ccgccgcgtc tgtatcatcg cttctgggcg gaaaaagcgt ttgttctcgg
    13321 ctgggaaatc tcgatggtaa atgatgacca acacgataat tattttcttg agccgggagg
    13381 acgttttccg gcgatagaag aagatgaacc ggtgaaatgg ttattgtgcg gtgagtatgg
    13441 aattttgcgc taataacggg gaacgctagc gctgatatcc gctagcgtcc ttatttttac
    13501 tgcaccggct ccgtcgacgt aacttcacca ctggaaacta cgcccgcatt catggtttga
    13561 gtcacttgct gctttgcggc attcacggca tgcaattgcc cgctaaccgt aggtttcagc
    13621 gggacattga cctgaatatc gccactggcg gtaagctgaa tattgccgtc gccagtcaac
    13681 ggtaattcag gccatcccca atgttgcaaa atattcaccg gcacaccgcg tccattcagg
    13741 ctgatatggg tctgacgttg tggcgtttgt gaaacactgg cggtggcttc cagaatgcct
    13801 ttttcagtaa atgcactcag ttcgctgata ttcaccgtgc tgctgttggc agttagcgcc
    13861 agcgacggac gacggacatc aacacgatta aacgttgcgg cggcggcatt cagattcgcc
    13921 gagccactcc agacgcccca tttatgatcg gtaaccagcg tcagattggc accgtaacca
    13981 tcgagcgcgg tgagctgcca cgggaagtca gggtcgatat caatgatcag attgcggctg
    14041 gcgctaaatc tcttcagttg caggctgttt aaccaaccgg gtgtcgtttc catccacaac
    14101 tgttgccagt ttttgggcaa ggtatattcc agtccggcaa ttgccgcatc atcgaggatc
    14161 agcgttttcc cgtcgcgttg ccagtttcct gacgttctga ccataccccc ttcccagcgg
    14221 ctggtgaact ggcgcagtgc tacgccctgc ggggcaaatt ccgcgtttat aatcggatca
    14281 aataaatgca gcgagccata aataaactcg ctggcgttca tcgacagttt accttcctgt
    14341 gtctgccagt catctttact gaaggtcatg ttgcgcaagc tgagatcgag gtcggccacc
    14401 gcccagtccg gaccttgcaa acgagcgtcg atgacttcca ggcgaccaat ctgcaacgac
    14461 gggacagagc gtaatggtgc aaagaagtcg gttagcgatt tttcgctttg tagacggata
    14521 tccgccatgc gcaggttttc cacttgccag ctgccgtcag cgttacgctg cgcgtttccg
    14581 gttaatgtcc cgcgggcgat gtcggcaccc aggttagtca gcgtaacgcg atcgttatca
    14641 atactgcctt caatcagtac attggtggca ggaacatcat tgagcgaaag cgatccggca
    14701 ctaaactgaa tctgtgcctt cgtacccagc actttaccgg cttctggtga ccacggaacc
    14761 acgccgccat ttacccgctg cgcgctcagt ttccattcgc tattcgggct attaaacgcc
    14821 atatcacgca gttgcagacg atcggctttg aacggtagcg gcgcggtctg gtcggtgaga
    14881 ttcagcgtcc cgttttccag caggatggta tcgacatggc gtggttcggt cagttgccga
    14941 ctgcttagcg caatgtcgac actttttgct accagggtcg cgggctggcc atcacggcca
    15001 aacgtgacgt tcttcagcac gatatgagat ggcgcggaaa aacggtgatc catcgccccg
    15061 aaggccagat gatagtcgct attctcggaa acccatgcgc tgatatgttc tgctccccag
    15121 cgagtttgca gaagaaaata gaggccagcg atcaccacta acagagcgat gagaatgtag
    15181 agaagcagct tcccaataaa tttcatggtc ttccatcccg tgaaatgcac ataagggagt
    15241 tatgcacgat ttacgcgcaa tcctcaaggc gggaatggtg aaagaggtga gactgcggcg
    15301 gtaattatct taccgccgcc agtgaattac tgtttttctg gtgggaaaat cagattcagc
    15361 acgatggcag taataccgcc cgcggcaatc ccggaggaga gcaggttttt cagccattca
    15421 ggggcaaact gcaaaatcag cggctgctga gacacgccca gaccgaccgc cagcgacagc
    15481 gcgataatca gaatcgcccg gcggttcagc ggctcacgag aaacgatacg cacaccggag
    15541 gcggcgatgg tgccaaacat tacaagcgtt gcgccgccca gaaccggttc tggaatgtgt
    15601 tgtacaaaac cgctcactgc cgggaacaga cccagcacga tcaacatcag cgcgacgaca
    15661 aaaccgacat agcggctggc aacaccggtt aactggatca ccccgttgtt ctgcccgaag
    15721 caggagttcg ggaaggtatt aaataccgcc gagacaaacg agttcaggcc gtttgccagt
    15781 acgccgcctt tcaggcgttt catgtacagc ggaccggaca ctggctgttc ggaaacgtca
    15841 gaggtcgccg tgatatcgcc aatggtttcc agcgaagtga tcataaagac cagcatcagc
    15901 ggcagcagca gactccattc aatgccaaga ccgtaataga gcggcgttgg caccataatc
    15961 agttcttgtg tcatcggttc gttgctttct ggcaacatgc ccataaacca cgccagcgca
    16021 tatccggccg ccatcgcaat caccagtgag gccacgcgta agtaagggtt acgttgacgg
    16081 ttaagcagga taattaaggc taagaccacg cctgccagca gcagattttt cggtgcgccg
    16141 aaggtgttat cgctcatggc tgcgtaaccg ccgccaatgg aggtcagtcc aacctgaatt
    16201 agcgacaggc cgataatcat caccacaacg ccagaaacca gcggcgtaat aatgcggcgc
    16261 gccagatgca gaacgcggga gatcaccatc tcggtacaac ttgccagcat caacgtgccg
    16321 aacaaagctg ccatcatggt aggaacatca gcaccaccgg tcttcagcgc tgtgccgccc
    16381 ataatcagcg gagcaacaaa gttgaagctg gtgccctgaa tagacaacaa cccggagcca
    16441 accggacccc aggccttaat ttgaataatc gatgccacac cggaggcaaa cagcgacata
    16501 ctaataatgt gttgcgtgtc ttgtgccggt aaacccagcg cctggcagat taatagcgct
    16561 ggcgtgatca ccgcaacgaa catcgccagc aaatgctgac aggcggcaaa cagagtttga
    16621 ggaagcggcg gacgatcttc aagacggtaa atcagttcgc tgttttgagt ctgcgcaacc
    16681 ggttgcgcat tttctgactc gagggtggaa acagacatcg aaaacaatcc cgtggtagca
    16741 aagcgggcat tttagctgac cgaaagagaa aagcaaacgt ttgccacatc ctcatctaaa
    16801 tatttaaatg agataaatgt acttttttat ataactttta gttgttttct gcttaaaatc
    16861 catgccattt ttctattttc agcgaagaat tcgaaccagg aaagcatgac tcgatactcg
    16921 tcatatttcg ccttactgca aatgcgcgat gaagtatgac gagtatgaaa gagtgatgcg
    16981 gacacaaagg agtaactatg tttcatctcg atactttagc aacgcttgtt gccgcaacgc
    17041 tgacgttgct gctcgggcgc aagttggtcc attccgtctc ctttttgaag aaatacacca
    17101 taccggaacc tgttgcgggt ggtttattag tggcgctggc gctgctgata ctgaaaaaaa
    17161 gcatgggctg ggaagtcaac tttgatatgt ccctgcgcga tccgttgatg ctggctttct
    17221 tcgccaccat tggcctgaac gccaaccttg ccagtctgcg agctggtggg cgtgtggtgg
    17281 gggttttcct gattgtggtt gttggcctgt tggtgatgca aaatgccatt ggcattggta
    17341 tggctagcct gttagggctt gatccgctga tggggctgct ggccggttct attacgcttt
    17401 ccggcggtca cggtacgggt gctgcatgga gtaaattgtt cattgaacgt tatggtttca
    17461 ccaacgcgac agaagtggcg atggcctgtg caacgttcgg tttggtgctg ggcggcttga
    17521 ttggcggtcc ggtggcgcgc tatctggtga aacactccac cacaccgaac ggtattccgg
    17581 atgaccagga agttccgacg gcgttcgaaa agccggatgt gggccgcatg atcacctcgc
    17641 tggtgctgat tgaaactatc gcgctgattg ctatctgcct gacggtgggg aaaattgttg
    17701 cgcaactttt ggctggtact gcttttgaac taccgacctt cgtctgtgta ctatttgttg
    17761 gcgtgattct gagcaacggt ctgtcaatga tgggctttta ccgcgtcttt gagcgagcgg
    17821 tatccgtgct gggtaacgta agcctgtcgt tgttcctggc gatggcgctg atggggctga
    17881 aactgtggga gctggcttcg ctggcgttgc cgatgctggc gattctggtg gtacagacca
    17941 tcttcatggc gttgtacgcc atcttcgtta cctggcgcat gatgggcaaa aactacgatg
    18001 cggcagtgct ggctgcgggt cactgtggtt ttggcctcgg tgcaacgcca acggcaatcg
    18061 ccaacatgca ggcgatcact gaacgctttg gcccgtcgca catggcgttc ctggtcgtgc
    18121 cgatggtcgg tgcgttcttt atcgatatcg tcaatgcgct ggtgattaag ctgtatttga
    18181 tgttgccgat ttttgccggt taaccgatga agcggcggtc ttctcaccgc cgctttttac
    18241 gcattcgagt aacgttctgt ttctggcatc cagcgttcta tcagggcttt tgcctgttgt
    18301 gggtaacgtt cgtgaatatg tcgcgccagg cgctgaactt ccgggatcat cgcctgatcg
    18361 cgcagtaaat ccgccacttt aaattcagca ttacccgtct gacgtgtacc taacaattcg
    18421 ccagggccgc gaatctccag atctttctgt gcaatcacaa aaccatcgtt gctgtcgcgt
    18481 agtacctgca ggcggatttg cgcggttttg gagagcggcg ttttgtagag cagcacgcag
    18541 tgagaagcca ccgcgccacg acctacacgc ccgcgaagct ggtgtaactg cgccagaccc
    18601 agacgctccg ggttttcgat aatcatcaga ctggcattgg gtacatcaac accgacttca
    18661 atgacagtag tggcaaccag caggtgtagc tcgccttgtt taaacgatgt catcaccgcc
    18721 tgtttctcgg cgggtttcat ccgtccgtgt accaggccaa cattcaactc tggtagcgcc
    18781 agtttcaact cttcccaggt cgcttccgcc gcctgcgctt ccagtaattc cgactcttca
    18841 atcaacgtac aaacccagta cgcctgacgc ccttcagtca tacaggcgtg gcgcacgcgg
    18901 tcaatgatgt cggtacggcg ggtatcagga atagcgaccg tagtcactgg cgtgcggcct
    18961 ggtggcagct catctatcac cgaggtatcg agatcggcat acgcagtcat cgccagcgtg
    19021 cgggggatgg gcgtggcggt catgatcaac tgatgcggat ggaagccctg ctgctggcct
    19081 ttctcccata acgccagacg ctgatgcacg ccaaaacgat gctgttcgtc gataatcacc
    19141 agcgccaggc cgttaaactg cacctgttcc tggaaaatgg cgtgcgtacc aacaatcatc
    19201 tgcacctgac cgctggcgat ggcttcttgc tgagccagtc gtgctttacc tttctgtttt
    19261 ccggcgagcc agcctacttc gataccgagc ggtgcaaacc agttacggaa gttattggcg
    19321 tgctgctcgg cgagtaattc ggttggtgcc atcaatgcca cctgtttgcc gtgcgcaatc
    19381 gcacgcaacg cggcgagggc ggcgaccagc gttttaccgg aacctacatc gccctgcacc
    19441 agacgcatca tcggcacatc cagcgccata tcgcgctcga tctccgccac tacgcgtgcc
    19501 tgtgcgcccg ttggcttgaa cggtaaggcg gcgaggagtt tatttttcag cgcgtcattg
    19561 gcgctcagcg gctgagcatg aaaacgttgt gcaccggcac gtaacgccaa catgctgagg
    19621 ttgtgcgcca gcaactcttc cagaatcagc cggcgttgtg ccggatgctg cccggtttcg
    19681 agatcgctaa gctgtagcgt cggcggtggg cggtgcaaag tgcgcaacgc ttccggtagc
    19741 gtcatcattc cttgtgacag ttccggcggc aggagttctt caatggcgca tgtgtcgagc
    19801 agatccagcg cctggtcggt taatttacgc agcgtagcct gctttacgcc ttccgtagtt
    19861 gggtaaaccg gcgtgagcgt ttcctgtaac tctggcgtgc tgagatcgcc ctgtacgcgg
    19921 tattccgggt ggatcatctc cgcaccatat ttgccgcgct ttgcttcgcc ataggccagc
    19981 acgcggcggc ctgtcgccag gctatttttc attgccgcat tgaagttgaa aaagcgcata
    20041 gtgagaatgc cggaaccgtc gctgatctgg caggtcatca tccgccgacc gccgaaggag
    20101 atattgcagt tcagcacttc gccttccacc gtggcataaa cacccggcag tagttcaccg
    20161 atggggtaga gatgtgtgcg atcttcgtag cgcagaggaa ggtgtaagag caaatcctgt
    20221 acggtatgca ggttgatttt cgccagcttg ttactaagcg ctgcgccaac gcccgttagg
    20281 gaactgagcg ggacagcatc taacaggcga cctttcatcg cgcttaccct gcggcctgca
    20341 tggtggacca ccagtcagca tcggcttcaa tctcgccttg ctgattaacg tgggggtagg
    20401 gcagaccttt gcgttttgcg actttcgcca gcaccggata gccgccttca aacagcaggc
    20461 gttgttgctc ggcttccggc aacatgctgt tttcacgcag gtacatgccc gcattttgcc
    20521 gctggcgctg ggcttcgtaa agaatgaggg ctgaggcaac ggaaacattc agcgactgca
    20581 ccatgccgat catcggaatg atgatatcct gatccgccag ggccaacgct tcctgcgtga
    20641 tgcccgtttt ctcctgtccc atcaaaatac aggtcgggcg agtgtaatca atttcgcgga
    20701 aatcaacagc gttatcagaa agatgggttg ccagaatctg catgccctgg cctttcagat
    20761 gagcgacggc atcgccaatg gtgcggtgcg ttttcacctg tacccagctg ttactacccg
    20821 cagctgccga agccatggtg cgcatccggc tgccaggcca gacagcatga acttcatgta
    20881 cgccaacggc atctgcggta cgaataatcg cagaaacgtt atgaggtttg tggacctgct
    20941 ccatgcagac ggtcagatca ggctgccgcc tggcgagcat ttcgcagatg cgtgcataac
    21001 gtgttgggtt cataaaacat taatttcggt ttcgggtgac tttaatcacg tctggcatca
    21061 cgcggatttt gcgcatgata ttcgccagat gcacacggtc acgggcggtc agacgaataa
    21121 aggcgctata gacgcgacca tctttctctt ccgtattcaa actttgaata ttcgaggtcg
    21181 tggtgttaat tgccgccgtc aggtttgcca gcgcgccctg atgattgaac atctccacct
    21241 tgatttcggt gatgaattcc tgcgccgtct ctttatccca ttcaacagcc ataaacttct
    21301 ctggctcttt ctggtagcca cggatgttac ggcaggattc atggtggatc accagacctt
    21361 taccggggct gacgtgggcg ataatcgggt cgccaggaat tgggcggcag catttcgcaa
    21421 aggtgatcag cacgccatcg gcacctttaa tgggcagatg tccgtgactt tgggttgccg
    21481 gtggaatgga ggcgtcccca tgttgcagat ttttcgcgac caccacgctc attgcgttac
    21541 caaggccgat ttctgccagc agatcgtcaa gcgttgccag cttcatgcgg tccagctcgc
    21601 gctgaatatt ttcctgcggg atttcattga gcttacggct accacccaac gcatggttga
    21661 gcagacgacg gcccaggctt acagaatcat cacgcttgag gtttttcagc aactgacgaa
    21721 ttttggcgcg cgctttcgag ctgacgacaa agttcagcca cgcggcattc gggcgagcac
    21781 ccggtgcggt aatgatttca acggtttgac cgctagtaag cggctgcgac agcgggtaag
    21841 gctggcggtc gacgcgtgcg cccacgcagg catggccgat atcggtatgc accgcataag
    21901 cgaagtcgac gggcgttgca ccggcaggca gttcgacaat gcgcccttct ggtgtgaaaa
    21961 cgtaaatctc atccgggaag agatcggatt taacgctctc gataaattca aacgagctac
    22021 cggcactctg ttgcagctcc agcaggcttt gcatccagcg ctgggcgcgt atttgcgcgg
    22081 tagtgctggt ttcgccgtgc tctttataag cccagtgcgc ggcaacaccc atctccgcca
    22141 tctgatccat atcttcggta cggatctgga cctcaaccgg cacgccgtgc gggccaatca
    22201 tcgaggtgtg caaagactga tagccgttcg cttttggaat ggcgatatag tctttcacgc
    22261 ggcccggacg cggcttgtac aggctgtgca tctggcccag cacgcgataa caggtgtcag
    22321 aatcattgac gatcacgcgg aaagcgtaga tgtccatgat tgagtgaaaa cgctgctctt
    22381 tgagcaccat tttgcagtaa atcgaataaa gatgcttttc gcgaccactg acgcggcacg
    22441 gtattcccgc ttcctgcaaa cgcccttcga tttcagaaag aatcttctgg atcatctctt
    22501 tacggttgcc gcgcgcggct ttcaccactt ctttgattac gcgataacgg ttgggataca
    22561 gcgcctcaaa acccagctcc tcgagttcgg ttttaatgtg gtggatacct aaacggtgcg
    22621 ccagcgggct gtatatttcg agagtttcac gggcgatgcg gcgacgtttg tccgggcgaa
    22681 gtgagcccag cgtgcgcatg ttgtgggtac ggtcggcaag tttgatgaga atgacgcgga
    22741 tatcctgcac catcgccata atcatcttgc gaaagttttc ggcctgcgcc tctttcttat
    22801 cgcggaactt gagtttatca agtttcgaca ccccctctac cagctcggcg acgcttttac
    22861 caaaaagctg ttccatgtcc tggtaggtgg cgggtgtatc ttcaatcaca tcatgcagca
    22921 gcgccgccat cagcgtttca tagtcgagtt tcatctcggc cagaatgcag gcaaccgcca
    22981 ccggatgcgt gatatagggt tcaccgcttg aacgtgtttg cccctcgtga gcatcacgtg
    23041 caacgagata cgcctgccgc agacgcttga tttggtcttc cggcaggtag ttttgaatca
    23101 gctgattcag gctttcaaac agatacaagg gcgacccgct ttgtgattaa cgacgacctt
    23161 cagcaatagc ggtaacggct tgtaattcag cggcttcctg ctcttgctgc tcctggcgtt
    23221 cgcgaacgtc gaggatctgg ttgttgatca gaccttcttc gatttcgcgc agcgcgatta
    23281 cagtggtttt atcgttttct tccggtacca gcggatcctt tccgcctacc tgcatctgac
    23341 gagcgcgacg cgcggcgacc agtaccaggt caaaacggtt accaattttc tctacagcgt
    23401 cctgaacagt tacgcgtgcc atacttaaaa agctccacag gtgaagaaat gactgggcat
    23461 gatactgaaa tcaggttcag tctgccaaca atttgctgat taaagcgtca tgacgctgct
    23521 tttggcggct catgcgcaga cgttcggcgc gaataatggt cttcaaatcg gtcaacgcgg
    23581 tatcgaagtc atcattcaca atcaggtaat catattcggc gtaatggctc atttctgcaa
    23641 cagcttgcgc catacgcttt gcaatgacct cttcgctgtc ctgaccgcga ccgcgtagac
    23701 ggcggtccag ttcgatttta gacggcggta aaataaagat actccgcgcg tgcggcatct
    23761 tctggcgaat ttgctgcgca ccctgccagt cgatatcgag aaaaacatcg acaccggtcg
    23821 ccagtacttg ctcaatggcc tcacgcgaag tgccatagta attaccaaaa acttctgcgt
    23881 gttcgaggaa cgcatctcta ctaatcattt ctttaaattc atcatgatta acaaagaaat
    23941 aatgttcacc gtggacttca ccaggacgcg gttggcgtgt ggtgtgtgaa acagaaacct
    24001 gggtgtcata caacggttgg gtttttaata aagcctgaat caggctggat ttacccgcgc
    24061 cactgggggc agaaacaata taaagcgtgc cttgagccat gagtatcttt cgtatgtgat
    24121 tagcgaaata aagcctacat acgagcttat tatacacggc gcggccatgt gacgtagccc
    24181 ttgctcacac tttttgcgca aagttgttgc gttttgcgta gctgcttccg catttgcctg
    24241 tgattcactg caataaagac gattctcagg aagcgtcctc gcagactccg tttttgccac
    24301 tcggctttgc cttcaccaca ttgtatatct gcctgactat ctacagcgga ggtgatgatg
    24361 aaagtatgga tggcgatatt aataagtatc ttgtgctggc aatcatcggt gtgggcggtc
    24421 tgtccggcct ggtcgccagc cagagcacag gaagaaattt cccgcctgca acagcaaata
    24481 aaacagtggg acgatgacta ctggaaggaa gggaaaagtg aggtggaaga cggtgtttac
    24541 gatcagttaa gcgcccgtct tacgcagtgg caacgctgtt ttgggaacga gacccgcgat
    24601 gtgatgatac cgcctttaaa cggtgcggtt atgcatccgg ttgcccatac gggtgtacgc
    24661 aaaatggcgg ataaaaacgc attaagtctt tggatgcgcg aacgtagcga tctttgggtg
    24721 cagccaaaag ttgatggcgt tgcggtaacc ctggtttatc gggacgggaa actgaacaaa
    24781 gcaatcagtc gcggcaatgg cctgaaaggc gaggactgga cgcagaaagt tcgcttaatt
    24841 tccgctgtgc cgcaaaccgt tagcgggcct ttagccaaca gcacgcttca gggggaaata
    24901 tttctcaagc gtaaggggca tatccaacaa caaatggggg gaataaatgc ccgcgcaaaa
    24961 gttgctggcc tgatgatgcg ccaggggaat agcgatacgc taaactcact ggctgttttt
    25021 gtctgggcat ggccggatgg accgcattta atgaccgatc gtttaaagga tctggctacc
    25081 gcaggtttta ctttaacgca gacgtatacc cgcgcggtta aaaatgctga tgaggttgcg
    25141 cacgtacgca atgagtggtg gaaagcaaaa ttacccttcg tcaccgatgg cgtggttgtg
    25201 cgagcggcga aagaacccga atcccgtcat tggctaccgg gccaggcgga gtggctggtg
    25261 gcctggaaat atcaacctgt agctcaggtt gccgaagtga aggcgattca gtttgcggtg
    25321 ggtaagagcg gtaaaatatc ggtggttgcg tcacttgtac ctgtcatgct ggatgataaa
    25381 aaagtccagc gggtgaatat tggttccgtc aggcgctggc aggagtggga tattgcgcct
    25441 ggtgatcaga tcctcgtcag ccttgccggt caggggattc ctcgcattga tgatgtggtc
    25501 tggcgcggag cagaacgtac aaaaccgaca ccaccagaaa accgctttaa ctcgttgacc
    25561 tgctactttg cttctgatgt ttgtcaggaa cagttcattt cacgcttagt ctggctgggg
    25621 tcaaaacagg ttctggggct tgatggcatt ggtgaggccg gctggcgcgc cctgcatcag
    25681 actcatcgct ttgagcatat cttttcctgg cttttattaa cgccagagca attacagaac
    25741 acgccgggga tcgcgaaaag taaaagtgcg cagttatggc atcagtttaa tctggctcgt
    25801 cagcagcctt ttactcgctg ggtgatggca atgggaatac cgctaactcg ggcggcgctt
    25861 aatgccagtg atgaacggtc ctggtcgcaa cttttattta gcacggaaca gttctggcag
    25921 cagctgccgg ggactggatc ggggcgcgcc agacaggtta ttgaatggaa ggaaaatgcg
    25981 caaatcaaga agctgggcag ttggctggct gcccagcaga tcacaggttt tgaaccttag
    26041 tgaccttcgt ggctgtagta aaagaccggt aatcccagct taagacgtag cgccagtaaa
    26101 cgggcaaaaa agccgaatac cagggtggag ataatcacca catcatggtt agaaacatag
    26161 tgttgcagcg cgatgtacag cacggcggag gcaaatgaga cacccgcata caactctttc
    26221 tggaatacca gtgggatgcg tttacagaac atatcgcgca aaacgccgcc aaacacgccg
    26281 gtggttaccg ccgcgacaac ggcaataatc gggccgtgcc ccatatccag agcaacctgt
    26341 gcgccgatga tagaaaatac caccagtccg agcgcatcga gcaccagaaa cactttgcgc
    26401 agataaggca ttacaggagc aactatagtg gtgagtactg cagcggtagc gacgataatc
    26461 acatattccg ggtgtttgac ccagccgagc ggatagtggc ccagcagaat atcgcgcact
    26521 gaccctccgc caattgccgt ggcggtcgca ataataatta cgccaaatgt atccatgcgc
    26581 cgtcgtccgg ccgccagcgc ccccgtcatg gcttcggcag taatgccaac caaatacaaa
    26641 atgtgtaaca gcatggttct ctccctaaaa atctgtctgg aagggtagcg atttgtgcgc
    26701 attgtcacga ttgagatttt ttaaggagag aatagattga taatttgtag ttatgtgaaa
    26761 ttgctatttt ctgtagtaag aatgcatttt tctgattttg tgataagtaa aatgcattag
    26821 aaaaagtatg gagtaaataa atatgaggac gaaactatat gcgtagcgcc gctgtaatta
    26881 acaacggcct acggagatat gtcgcttact cgatattctg aatctgctcg cgcatctgtt
    26941 caatcaacac tttcagctcg atggcggagt ttgtcacttc ggcgttgata gatttcgacg
    27001 caagagtgtt cgactcgcgg ttgaactcct gcatcataaa gtccagacga cgaccaacgg
    27061 cttctttttt cttcagaatg ttgtaggtct ctttgacatg cgcttcgagg cggtccagtt
    27121 cttcggcaac gtcaattcgt tgtgccagca gaaccaactc ctgctccaga cggttgtttt
    27181 ccagttgcac ctgagcatct tccagcttcg ctaccagacg ctcacgctgc cattgcagga
    27241 tttccggcat atgggcgcgg actttgacca cttcggcggt gacgccttcc agacgctgct
    27301 caatcaacac tttcagcgcc tgaccttcgg tttcgcgcgc gatgataaag tcatccaggg
    27361 tgccatccaa cgccgcgaga atttcagctg caatcgcgtc gagatcttgc tcctgggctg
    27421 ccatcacgcc cggccagcgt agaatatcaa ccgggttgat ttctccttcg tcgctctgca
    27481 tttttaccca gttcgcggca gttaccagct gtttagccag tttttcgttg aggatcagct
    27541 caccttgcgc gctaacatct ggctcatagc gcagagtaca ttccacttta ccgcgcgtca
    27601 ggcgagaacg aatacgctcg cgaacgacag gttcaaggct acggaactgc tccggcagac
    27661 gaaagtaagt ttccagataa cgctggttta ccgagcgcat ttcccaggtt gcgctccccc
    27721 attcaccctt gatttcacgc cgggcgtagg cggtcatact gcggatcata gacgttcctg
    27781 tttataaaag gagaggtgga aggattatag ccatcgatgc cttgtcagga taggaataac
    27841 cgccggaagt ccgtataatg cgcagccaca tttgtttcaa gccggagatt tcaatatgcg
    27901 tccagcaggc cgtagcaata atcaggtgcg tcccgttacc ctgactcgta actatacaaa
    27961 acatgcagaa ggctcggtgc tggtcgaatt tggcgatacc aaagtattgt gtaccgcctc
    28021 tattgaagaa ggcgtgccgc gcttcctgaa aggtcagggc cagggctgga tcaccgcaga
    28081 gtacggtatg ctgccgcgtt ctacccatac ccgtaacgcg cgtgaagcgg cgaaaggtaa
    28141 gcagggtgga cgcacaatgg aaatccagcg tctaatcgcc cgtgctcttc gcgcggcagt
    28201 agatttgaaa gcactgggtg agttcaccat tacgctggac tgtgacgtgc ttcaggctga
    28261 tggtggcacg cgtaccgctt cgattacggg tgcctgcgtg gcgctggcag atgcgctaca
    28321 gaagctggtg gaaaacggca agctgaaaac taatccaatg aaagggatgg tagccgcggt
    28381 ctctgtcggg attgtgaacg gtgaagcggt ttgcgatctg gaatatgttg aagactctgc
    28441 cgcagagacc gacatgaacg tagtgatgac cgaagacggg cgtatcattg aagtgcaggg
    28501 gacggcagaa ggcgaaccgt tcacccacga agagttactc accttgttgg cgctggcccg
    28561 agggggaatc gaatccattg tagcgacgca gaaggcggcg ctggcaaact gatttttaag
    28621 gcgactgatg agtcgccttt tttttgtctg tagaaaagta agatgaggag cgaaggcatg
    28681 aaaccatatc agcgccagtt tattgaattt gcgcttagca agcaggtgtt aaagtttggc
    28741 gagtttacgc tgaaatccgg gcgcaaaagc ccctatttct tcaacgccgg gctgtttaat
    28801 accgggcgcg atctggcact gttaggccgt ttttacgctg aagcattggt ggattccggc
    28861 attgagttcg atctgctgtt tggccctgct tacaaaggga tcccgattgc caccactacc
    28921 gccgtggcgc tggcggagca tcatgacctt gacctaccgt actgctttaa ccgcaaagag
    28981 gcaaaagacc acggtgaagg cggtaatctg gttggtagcg cgttacaagg acgcgtaatg
    29041 ctggtagatg atgtgatcac cgccggaacg gcgattcgcg agtcgatgga aattattcag
    29101 gccaatggcg cgacgcttgc aggcgtgttg atttcgcttg atcgtcagga acgcgggcgc
    29161 ggcgaaattt cggcgattca ggaagttgag cgtgattaca actgcaaggt gatctctatc
    29221 atcaccctga aagacctgat tgcttacctg gaagagaagc cagaaatggc ggaacatctg
    29281 gcggcggtta aggcctatcg cgaagagttt ggcgtttaac gaaactcgcc ggatgaaaag
    29341 tcatccggcg tcatattact gcaactgtgc ggcaattagc ggccagcggg cgtcaaaatc
    29401 atccgtcggg cggtatttaa actcgctgcg gacaaatcgt gacagcatac cttcacaaaa
    29461 tgccagcaac tggcttgcca gcagggtttc atcggtggtg taaccttcac cctcacgcat
    29521 tctcttttca cgcaatacct gacgcaactg cgcttcaata cgctcgaaca gctggttgat
    29581 gcgcccttgc agacgatcct gttcgaacat tagcgcatga ccagtgagga tgcgagtcag
    29641 gccaggatta cgctcaccaa aaccgaggag caacaacacg atcagacgca ggcgcgctgt
    29701 ggtgtctttc tcatctttca gaatcaggtt gatacgagta atcaggctat cttcgataaa
    29761 ctcaatcagg ctatcgaaca tgcgggtctt actggggaag tggcgataca gtgccgcttc
    29821 ggaaacgccg acagaggcgg ccagttttgc cgtcgtgata cgttggcttc catcgctgga
    29881 ttccagcatc agcgccagag actgaagtat ttcctcgcga cggttccttt tcgcagtttg
    29941 tttttctgcc atgttacaaa atacccctga aaataagcac ttgccaggcg gcacccacgc
    30001 tatgaccgca aacgaaatgt ttgcggctat gttatgacgt tattcggatg cgtatgtgtt
    30061 actgacgacc agagtgacca aagccgcctt caccgcggtc ggtggcgtcg aaatcttcca
    30121 ccagattaaa ttcagcctgt actaccggaa caaaaatcat ctgggcgatg cgttcgccag
    30181 gttgaatggt gaagctgtcc tgaccacggt tccacacgga aatcatcaac tggccctgat
    30241 agtcagaatc gatcaatcct accaggttac caagcacgat accgtgctta tgtcccaatc
    30301 cggagcgcgg tagcatcatt gccgccagtg aaggatcggc aatatgaatc gccagcccgg
    30361 tcggaaccag cgtagtgtca cccggagcca gttctacggc gtcgtcgaga caggcacgca
    30421 ggtcaagtcc ggcagagcca gaggtggcat aagtcgggag cggaaattcc ttcccaacgc
    30481 gcgggtccag aatcttaacg tcgatttttt tcatcataac gggtcacgat ctcgtcgagt
    30541 aataattggc caaggagctc tttgcgctca agcggtaaga ctttatctcc gtcctgccag
    30601 aaaaggtgta atgcgttgtt gtcgctgtta aatccttgag ttggctggga aacatcgttc
    30661 gcgcagatca gatcaaggtt tttacggata cgtttttgcc gggcgtattc ttccacatta
    30721 tttgtttcgg cggcaaatcc aacgacgtaa ggtcgatggt cttttagtgc ggcaacgcct
    30781 gcgacgatat cggggttttt aaccattttt attgttaatt catcaccctg cgtggcctgc
    30841 tttttgattt tttctggggc cacggtagct gcgcgataat ccgccacggc ggcgcaaccg
    30901 ataaaaatat tttgctgctg tactgaagca ttcacggcgg cttccatttc cagcgcggtc
    30961 atcacatcaa cacggttaac aaacggtggc gtcggtagtg aaaccggacc tgataccagc
    31021 gtgacgttcg cgccacgacg ggctgcggcg gcggcgatag caaaacccat cttgccggag
    31081 ctgtgattag agatataacg cacgggatcg agcggttcac gcgtcggacc ggcggtaatc
    31141 ataatgttca gatgtttcag gtcgttgacg ggcgaaaaat gcgctaccgc catatccaca
    31201 atagttaacg gatcgagcat tcgtcctggg ccgatatcac cacaagcctg actgccgctg
    31261 tctggccccc agatgagcaa accacgtgag gcaagcacct ctaaattatg ctgggtggcg
    31321 gcggcacggt acatctgctg gttcatggcg gggagcacgg ctacaggcgc aggtgtagcc
    31381 agacaaatcg tcgataccag gtcattcgcc attccggctg caacacgggc aattaaatct
    31441 gccgtggcag gggcgagaat cactaaatca gcccattttc ccagctcaat atggcccata
    31501 gcggcttcgg ctgccgggtc cagcagactg tcggaaacgg gataaccaga aaccgcctgc
    31561 aagctaagtg gggtgataaa ggcttttgcc gcttcggtca tggctacgca gacatcggcc
    31621 ccgcgatcgc gcaaacgacg caccagttca ggggttttat aggcagcaat accgccgcta
    31681 acgccgagaa cgattttttt accggccagg ctcatgatga tttttcctgt tgggtgacac
    31741 cagaagttgg cgattttatc acaatacttt tgttgtcgtg ccttcacctg agattcactt
    31801 tgcgaggcgc tttccaggat tgaaaactgg ccgtcgattt aaaggaacgg ctatgacagg
    31861 atgcgagcac cacaaaggag gtgaaggtga aaaacaatgt acagctgttg atgccgcgcg
    31921 aaaaaatgct gaagtttggt attagcgcct taacggatgt cgagctgctg gcgctatttc
    31981 tgcgtaccgg aacgcgcggt aaagatgtat taaccctggc aaaagagatg ctggagaatt
    32041 tcggctctct ttatggcttg ttaacctctg aatatgagca atttagtggc gttcatggaa
    32101 ttggcgtggc gaaattcgcc cagttaaagg ggattgccga actggcgcgg cgttactaca
    32161 acgtacggat gcgtgaagaa agccctttac tcagcccgga gatgacgagg gaatttttac
    32221 aaagccagct cacgggcgag gagcgggaga tctttatggt gatctttctc gactcccaac
    32281 acagggttat aacgcatagc cgtctttttt ccggcacgct aaaccatgtt gaagtccatc
    32341 ctcgggaaat tatccgcgaa gcgataaaaa taaacgcctc ggcgctgatc cttgcgcata
    32401 atcacccttc gggttgtgct gaacccagta aagcggataa actcattact gaacggataa
    32461 taaagagttg tcagttcatg gatttacgcg tgctcgacca tatcgtgatt gggcgtggag
    32521 agtatgtttc ttttgccgaa cgcggctgga tttaacccgc tatgcgcgat ccttcgggat
    32581 ctttgtctgt tcgggacttg agcacatcgc tgagtcagcg tatactacgc cacctttgag
    32641 aatctcgggt ttggcatttg ggcctggcaa tcgagagttc acatagaact gcgatgaccg
    32701 ggctgtaaag cctgacgagg cgccaatacc ccatacgaag ctcgagctaa tttgattttt
    32761 ggagaataga catgtcccga gtctgccaag ttactggcaa gcgtccggtg accggtaaca
    32821 accgttccca cgcactgaac gcgactaaac gccgtttcct gccgaacctg cactctcacc
    32881 gtttctgggt tgagagcgag aagcgttttg tcaccctgcg cgtatctgct aaaggtatgc
    32941 gtgtaatcga taaaaaaggc atcgatacag ttctggctga actgcgtgcc cgtggcgaaa
    33001 agtactaagt acttagagga aataaatcat ggctaaaggt attcgtgaga aaatcaagct
    33061 ggtttcttct gctggtactg gtcacttcta taccactacg aagaacaaac gtactaagcc
    33121 ggaaaaactg gaactgaaaa aattcgatcc agttgttcgc cagcacgtga tctacaaaga
    33181 agcgaaaatc aaataatttc cgctttaatg taacaaaaaa cctcgccccg gcggggtttt
    33241 ttgttatctg cttgccccca tattgactgc atctgttcat tcctggagat gctatgcctg
    33301 aattacccga agttgaaacc agccgtcgcg gcatagaacc gcatctcgtt ggtgcaacca
    33361 ttcttcatgc ggtggtgcgc aacggacgct tgcgctggcc ggtttcagaa gagatctacc
    33421 gtttaagcga ccaaccagtg cttagcgtgc agcgccgggc taaatatctg ctgctggagc
    33481 tgcctgaggg ctggattatc attcatttgg ggatgtctgg cagcctgcgc atccttccag
    33541 aagaacttcc ccctgaaaag catgaccatg tggatttggt gatgagcaac ggcaaagtgc
    33601 tgcgctacac cgatccgcgc cgctttggtg cctggctatg gaccaaagag ctggaagggc
    33661 acaacgtgct ggcccatctt ggaccggagc cgcttagtga cgatttcaac ggtgagtacc
    33721 tgcatcagaa gtgcgcgaag aaaaaaacgg cgattaaacc gtggctgatg gataacaagc
    33781 tggtggtagg cgtagggaat atttatgcca gcgaatcgct gtttgcggcg gggatccatc
    33841 cggatcggct ggcgtcatca ctgtcgctgg cggagtgtga attgttagct cgggtgatta
    33901 aagcggtgtt gctgcgttcg attgagcagg gcggtacaac gctgaaagat tttctgcaaa
    33961 gtgatggtaa accgggctat ttcgctcagg aattgcaggt ttacgggcga aaaggtgagc
    34021 cgtgtcgggt gtgcggtacg ccgattgtgg cgactaaaca tgcgcagcgg gcaacgtttt
    34081 attgtcggca gtgccagaag taattgatgc gcgccggatg gcataccatc cggcataaac
    34141 tctacgctaa cttcgccatc agcgcctgat ggacattctc cggcaggaaa tgggtgacat
    34201 cgccctgatg gcgcgccacc tctttcacca acgatgaaga gataaacgac cactctttcg
    34261 acggcatcag aaacacactt tccagctccg gcattaagtg gcgattcata tgcgccagct
    34321 gcatttcata ttcaaaatcc gccaccgcac gcaggccacg aatcagcacc gtagcgtgtt
    34381 gattacgggc gaagttcgcc atcaaatcac taaacccgac cacttccacg ttctccagat
    34441 gcgcggttgc ctgctgtgcc agctccacac gctcttccag ggtaaacatc ggttttttac
    34501 tgggactagc ggcaatcgcc agaataacgt gatcgaacat ttgcgaggcg cgcgtcacga
    34561 tatcgatatg accattggta atgggatcga aagtacccgg ataaatcgcc cgtttttgca
    34621 taacaacctc aatgcgtttt cggtggcagg taaggttcca gcagttgaag cagacgctgt
    34681 agtgcgccct ggttttgata cagcacttca acggcatgac ggccatagaa actacggtaa
    34741 tcggcgtcgg tgagtaaaga ggaaacctct tttgcaagcg tagtggcatc ggtaacggta
    34801 atcagcccgc ttgcctgctc cagccgcgcg caaatgtctt taaagttaaa cgtatgcggc
    34861 cccatcaata ccggaatagc gtgtgcggcc gcttccagcg gattatgccc accacgttca
    34921 accagtgaac cgccaacaaa ggcgagatcg gcaatgccgt acagtaacat caactcgccc
    34981 atcgtatcgc caaccacaac ctgcgtgctg gtggagggga cttcccctga agatcgtgtg
    35041 atatagctta gtccagcctg gcggacaagg ttaatcgcat ccgggaagcg ttctggatga
    35101 cggggtacca ggatgagcaa taaattcggg aattgctgta acaatgcctg atgtgcggcg
    35161 atcaccacac tctcttcgcc ttcatgagtg ctggtggcaa tccataccgg gcggtgtggt
    35221 gcccactggc ggcgcagcgt cacggcttta gcagccaact gcggcgttac agaaatatcg
    35281 aatttcaggc taccggtaac ggtcacctga ttattttttg cgcccagcgc cacaaaacgt
    35341 gcaccatctt cttcattttg ggcggcaatc agcgtaatac gacgcagcaa gcggcggacg
    35401 aatttaccca gtttggcata acctgcggcc gagcgggcag agagtcgcgc gttagcgatc
    35461 accagcggaa ttttacgttt atgtagcgcc gcaatcaggt taggccatag ttcggtttcc
    35521 ataatcaaca ccagtttagg gtcgacttta ttcaggaaac ggttgagtgc atcgggcagg
    35581 tcatacggca gataaacgtg ctgaacatcc ttcccgaaag ccgattgtac gcgctccgaa
    35641 ccggttggag tcatggttgt tacggtaatc ggtaaatcag gataacgatg acgcagtgcg
    35701 cgcaccaacg ggatcgccgc cagagtttca ccgacggaga cggagtgcag cataatgccg
    35761 cctggtttta gcggatggcg gtaaaaaccg taacgttcac cccagcgttt tcgataggcc
    35821 ggagccttac gtccgcgcac ccagagccgt atccagatca gtggctgaat aaggtagaga
    35881 agggcggtgt aaagcaattc gagcatagta aatagctgac ttatggatgt gctggggatt
    35941 ctatgtattt agctgtggct ttaccattac ttttcccgtt tttgacttaa atagcaattt
    36001 acccgccaat tcttgctgaa catctatact ttttttgtat ttttatgcga ttcattgatt
    36061 tctgcagtac gtgcaggaag gaatcgcaga gcaacagtaa aaagaatatg gttgctaatg
    36121 attttatttg attgatttct ttattgaaaa tcaacaatgt gcttaaaaat cattcgggtc
    36181 ggattgccgc gaaagaagtg atacactagc gcgtcaatat cagtgcggta tcagtattca
    36241 ggtagctgtt gagcctgggg cggtagcgtg ctttttctgc ttcaccttaa tcggataatc
    36301 tcaacaaaaa gagttacttg tggataagcc atttcgaaga attttgctca ttaagatgcg
    36361 ttttcatggg gatatgttat taactactcc cgtcattagt tcgctgaaaa aaaattaccc
    36421 tgacgcaaaa atcgatgtgc tgctttatca ggacaccatc ccgatcctgt ctgaaaatcc
    36481 agagattaac gcgctctacg gcataaaaaa taaaaaagca aaagcctcag aaaaaattgc
    36541 caactttttt catctcatca aggtattacg tgccaataag tatgacctta tcgttaatct
    36601 taccgatcaa tggatggttg ctatactggt tcgcttatta aatgcccgtg tgaaaatttc
    36661 ccaggattat catcatcggc agtctgcttt ttggcgtaat agtttcactc atttggtgcc
    36721 gttgcagggt ggaaatgtgg tggaaagtaa cttatccgtg ctgacgccat tgggacttga
    36781 atcgttggtg aagcagacaa ccatgagtta cccgcctgca aactggaaac gtatgcgtcg
    36841 cgaacttgat cacgctggtg ttggacaaaa ttatgtggtt atccaaccta cggcgcggca
    36901 aatcttcaaa tgctgggaca acgccaagtt ttccgctgtg attgatgcct tacatgctcg
    36961 tggttatgaa gtcgttctga cgtccggccc agataaagac gatctggcct gcgtcaatga
    37021 aattgcgcag ggatgccaga cgccaccagt aacggcgctg gccggaaagg tgaccttccc
    37081 ggaacttggt gcgttaatcg atcatgcgca gctgtttatt ggcgttgatt ccgcaccggc
    37141 gcatattgcc gctgcagtta atacgccgct gatatcgctg tttggtgcga cggaccatat
    37201 tttctggcgt ccctggtcaa ataacatgat tcaattctgg gcgggagatt accgggaaat
    37261 gccaacgcgc gatcagcgtg accgaaatga gatgtatctt tcggttattc cggcggcaga
    37321 tgtcattgca gctgtcgata aattacttcc ctcctccacg acaggtacgt cgttatgatc
    37381 gttgcttttt gtttatataa atattttccc tttggcggtt tgcagcgcga ttttatgcgt
    37441 attgctcaga cagtcgccgc ccgaggccat catgttcggg tttataccca gtcgtgggaa
    37501 ggcgaatgcc ctgatgtatt tgaactgatc aaagtgccgg ttaaatcgca taccaatcac
    37561 gggcgcaatg cggaatattt tgcctgggtg caaaaacatt tacgtgaaca ccccgtcgat
    37621 agagttgttg gatttaataa aatgccgggg ctggacgttt attatgccgc tgatgtttgt
    37681 tatgccgaga aagtagcgca ggagaaaggc tttttctatc gcctgacgtc acgttatcgc
    37741 cattatgctg cctttgagcg ggcaaccttc gaacagggca agccgacaca gctgctgatg
    37801 ctgacagata agcaaatcgc cgatttccag aaacattatc agactgaagc ggaacgtttt
    37861 catattctgc caccggggat ttatcctgat cgtaaatata gccagcagcc agccaatagc
    37921 cgtgaaatct tccgtaagaa gaatggaata accgaacaac aatatttatt gttgcaggtt
    37981 ggttcagact tcacgcgtaa aggtgtcgat cgttccattg aagcacttgc ttcgttaccg
    38041 gattcgctgc gccacaacac attgctatat gttgttgggc aggataaacc gcgaaaattt
    38101 gaggcgctgg cagaaaaacg cggcgtgcgc agtaatgttc acttcttctc ggggcgcaac
    38161 gatgtctcgg aattaatggc ggcggcggat ttattacttc atcctgccta ccaggaagcc
    38221 gcgggaattg tactgctgga agcgataact gcaggattac cggtactaac aacagccgtt
    38281 tgtggctatg cgcattatat tgttgacgcc aattgcggcg aggctattgc tgagccattc
    38341 cgccaggaaa cattgaatga gattttacgc aaagcgttaa cgcaatcttc attgcgccag
    38401 gcctgggcgg aaaatgcgcg acattatgct gatacacaag atttatacag tctgccagag
    38461 aaagcggcgg acatcataac gggtggtctg gatggttgaa cttaaagagc cgtttgccac
    38521 gttatggcgc ggtaaagatc cttttgagga agttaaaacc ttgcagggtg aggtatttcg
    38581 tgaactggaa actcgccgca ctctgcgctt tgaaatggcg ggcaaaagct attttctcaa
    38641 atggcatcgc ggcacgaccc tgaaagagat aatcaaaaat ttactctcat tgcggatgcc
    38701 agtattaggc gcagaccgcg aatggaatgc gattcatcga ctgcgggatg tcggcgttga
    38761 tactatgtat ggggtggcat tcggcgaaaa aggcattaat ccgctgacca gaacctcgtt
    38821 tattattacc gaagatctga caccaaccat cagtctggaa gattactgtg ctgactgggc
    38881 gaccaaccca ccagatgttc gcgtgaagcg tatgcttatt aagcgtgtcg cgacgatggt
    38941 gcgcgatatg catgctgcgg gcattaacca ccgtgactgt tatatctgtc atttcctgct
    39001 gcacttgcct ttttccggta aggaagagga gttaaaaatt tcagtaattg acctgcaccg
    39061 ggcgcagata cgtgcaaaag taccgcgtcg ttggcgggat aaagatttga ttggtttgta
    39121 tttttcatca atgaatattg ggctgacgca gagagatatc tggcgattta tgaaggttta
    39181 ttttgggatg cctttacgta agatattatc ttttgaacgg aatttattga acatggcaag
    39241 tgttaaggcc gagcatatta aagagcgaac acaacgcaaa ggattataaa aatattaatc
    39301 agtatgtact ggaactaact tcattatgac tatttatttt ataaactggg ttgcagatta
    39361 tgaattaaaa atgatccagt acttgaaaaa aaagcacaag ataaaaaata taacaacacc
    39421 aaaaaaatac aactgggtta ataagaaaat ttcgaaatta gggatggata atgcatggtt
    39481 gggacgatta tttatcaaac atcacctaaa tgctgtaaaa aaggatgata tcattatatt
    39541 taatgacagt gtcattaata aaagtattaa caagcaaata ttaaaaaata ttaattgtca
    39601 taaagtatta cttctaagaa atactgtcag tgaaaatttt atttttgata acgctaatta
    39661 ttttgatatt atctatgatt ttgagcatag atttataggg aatgaaaaga tcaaggcaat
    39721 agaacaattt tttcctatag gaatggatga aattagaaat tatagtttat ctgacaaaaa
    39781 taacagtcag ccaatatgtt tttttcttgg tcgtgataaa ggacgtcttc aaataattaa
    39841 tgaattagcc gatagattaa caacactagg atgtaagtta gattttaatg ttgtcaaaga
    39901 taaaacatca tctccgactt caaagtattt gattgaaaaa caaatatcgt atgaagagaa
    39961 tattagaaga acattaaatg ctaatataat tgttgatata actaaagaaa ac
//
LOCUS       DAPOXO010000043        38958 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPOXO010000043 DAPOXO010000000
VERSION     DAPOXO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38958
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.043"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            289..855
                     /gene="mntP"
                     /locus_tag="ROH59_002601"
     CDS             289..855
                     /gene="mntP"
                     /locus_tag="ROH59_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HDX4805066.1"
                     /translation="MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRR
                     HGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
                     IIGKKAEILGGLVLIGIGVQILWTHFHG"
     gene            complement(852..1661)
                     /gene="rlmA"
                     /locus_tag="ROH59_002602"
     CDS             complement(852..1661)
                     /gene="rlmA"
                     /locus_tag="ROH59_002602"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HDX4805067.1"
                     /translation="MSFSCPLCHQPLLREKNSYICPQRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLREWLDEKATAVLDIGCGEGYYTHA
                     FADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELVRVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLKGFTLQQSDELCY
                     LMRLRGDEAVALLQMTPFAWRAKPEVWQALAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(1827..2036)
                     /gene="cspE"
                     /locus_tag="ROH59_002603"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(1827..2036)
                     /gene="cspE"
                     /locus_tag="ROH59_002603"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDX4805068.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            complement(2049..2192)
                     /locus_tag="ROH59_002604"
     CDS             complement(2049..2192)
                     /locus_tag="ROH59_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HDX4805069.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
     gene            complement(2862..3149)
                     /locus_tag="ROH59_002605"
     CDS             complement(2862..3149)
                     /locus_tag="ROH59_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HDX4805070.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTVESQKSVEDEDIIRLVAER"
     gene            complement(3224..3367)
                     /gene="mgrB"
                     /locus_tag="ROH59_002606"
     CDS             complement(3224..3367)
                     /gene="mgrB"
                     /locus_tag="ROH59_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HDX4805071.1"
                     /translation="MKKFRWVALVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            3526..3765
                     /locus_tag="ROH59_002607"
     CDS             3526..3765
                     /locus_tag="ROH59_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805072.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(3909..4700)
                     /gene="kdgR"
                     /locus_tag="ROH59_002608"
     CDS             complement(3909..4700)
                     /gene="kdgR"
                     /locus_tag="ROH59_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HDX4805073.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     MQILEGVEYKRSTERTIISTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF"
     gene            4877..6250
                     /locus_tag="ROH59_002609"
     CDS             4877..6250
                     /locus_tag="ROH59_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4805074.1"
                     /translation="MPKVQADGLPLPLRYGAILTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIGAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLIAAAILAVIAACVSGLRI
                     TQPRSRA"
     gene            complement(6296..7177)
                     /gene="htpX"
                     /locus_tag="ROH59_002610"
     CDS             complement(6296..7177)
                     /gene="htpX"
                     /locus_tag="ROH59_002610"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HDX4805075.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(7369..9417)
                     /gene="prc"
                     /locus_tag="ROH59_002611"
     CDS             complement(7369..9417)
                     /gene="prc"
                     /locus_tag="ROH59_002611"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HDX4805076.1"
                     /translation="MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTA
                     FEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
                     "
     gene            complement(9437..10135)
                     /gene="proQ"
                     /locus_tag="ROH59_002612"
     CDS             complement(9437..10135)
                     /gene="proQ"
                     /locus_tag="ROH59_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707288.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HDX4805077.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKSGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(10232..10729)
                     /gene="msrC"
                     /locus_tag="ROH59_002613"
     CDS             complement(10232..10729)
                     /gene="msrC"
                     /locus_tag="ROH59_002613"
                     /EC_number="1.8.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="HDX4805078.1"
                     /translation="MNKAEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDVNW
                     AGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHAFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLEKVLATTDYKKFF
                     ASVAG"
     gene            10859..12142
                     /gene="yebS"
                     /locus_tag="ROH59_002614"
     CDS             10859..12142
                     /gene="yebS"
                     /locus_tag="ROH59_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HDX4805079.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDAITGAMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLLLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            12111..14744
                     /gene="yebT"
                     /locus_tag="ROH59_002615"
     CDS             12111..14744
                     /gene="yebT"
                     /locus_tag="ROH59_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HDX4805080.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIAGWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLSSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVIIKLELPGGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEMTVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLQEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPRRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            14824..16263
                     /gene="rsmF"
                     /locus_tag="ROH59_002616"
     CDS             14824..16263
                     /gene="rsmF"
                     /locus_tag="ROH59_002616"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HDX4805081.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPVLPAPKYKVGNFPFSPVKD
                     REAGQIRQAAASVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALASPDNVNAFELTPQEAEEWYRGRDVYPHAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTGNA"
     gene            16380..16616
                     /locus_tag="ROH59_002617"
     CDS             16380..16616
                     /locus_tag="ROH59_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HDX4805082.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA"
     gene            16721..16912
                     /locus_tag="ROH59_002618"
     CDS             16721..16912
                     /locus_tag="ROH59_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HDX4805083.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRHGGCF
                     PIEDFIDGFWRPAQEYGDF"
     gene            complement(16913..17569)
                     /gene="pphA"
                     /locus_tag="ROH59_002619"
     CDS             complement(16913..17569)
                     /gene="pphA"
                     /locus_tag="ROH59_002619"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDX4805084.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVRAVRGNHEQMAMDALASRQMSLWLMNGGD
                     WFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERQKGQGIAGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTLVQLQ
                     "
     gene            complement(17964..18305)
                     /locus_tag="ROH59_002620"
     CDS             complement(17964..18305)
                     /locus_tag="ROH59_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HDX4805085.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTKAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(18318..19190)
                     /gene="copD"
                     /locus_tag="ROH59_002621"
     CDS             complement(18318..19190)
                     /gene="copD"
                     /locus_tag="ROH59_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HDX4805086.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLTKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWSDVFSPNIWLAVLQTQFGGVWLWQIVLAL
                     VTLIVALMQPQNMPRLLFMLTTAQFILLAGVGHATLNEGVTAKIHQTNHAIHLICAAA
                     WFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTHWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(19194..19568)
                     /gene="yobA"
                     /locus_tag="ROH59_002622"
     CDS             complement(19194..19568)
                     /gene="yobA"
                     /locus_tag="ROH59_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HDX4805087.1"
                     /translation="MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYT
                     VDWHVVSVDGHKTKGHYTFSVK"
     gene            19707..19937
                     /gene="holE"
                     /locus_tag="ROH59_002623"
     CDS             19707..19937
                     /gene="holE"
                     /locus_tag="ROH59_002623"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HDX4805088.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            20039..20695
                     /locus_tag="ROH59_002624"
     CDS             20039..20695
                     /locus_tag="ROH59_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDX4805089.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSYGACLGRRSRTITVVDEQPQGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEHGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            20719..21381
                     /gene="exoX"
                     /locus_tag="ROH59_002625"
     CDS             20719..21381
                     /gene="exoX"
                     /locus_tag="ROH59_002625"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HDX4805090.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLE
                     NT"
     gene            complement(21378..23438)
                     /gene="ptrB"
                     /locus_tag="ROH59_002626"
     CDS             complement(21378..23438)
                     /gene="ptrB"
                     /locus_tag="ROH59_002626"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HDX4805091.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVDPSFVWANDSWTFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEIADAEPFVFLPRRKDHEYSLD
                     HYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRDNIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDNHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPAD"
     gene            complement(23647..24306)
                     /locus_tag="ROH59_002627"
     CDS             complement(23647..24306)
                     /locus_tag="ROH59_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HDX4805092.1"
                     /translation="MANWLNQLQSLLGQSRSSTSSSADQGLGKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ERLILALVFAAKSDGHIDAKERAAIDLQLREAGVEEKGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVREGIERDLEQQKRTLA
                     E"
     gene            complement(24633..24989)
                     /locus_tag="ROH59_002628"
     CDS             complement(24633..24989)
                     /locus_tag="ROH59_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HDX4805093.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(25056..25346)
                     /gene="yebG"
                     /locus_tag="ROH59_002629"
     CDS             complement(25056..25346)
                     /gene="yebG"
                     /locus_tag="ROH59_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HDX4805094.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            25480..26658
                     /gene="purT"
                     /locus_tag="ROH59_002630"
     CDS             25480..26658
                     /gene="purT"
                     /locus_tag="ROH59_002630"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HDX4805095.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     ADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEELQLPTSTYRFADSENLFREAVAAIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAHAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(26714..27355)
                     /gene="kdgA"
                     /locus_tag="ROH59_002631"
                     /gene_synonym="eda"
     CDS             complement(26714..27355)
                     /gene="kdgA"
                     /locus_tag="ROH59_002631"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDX4805096.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPIAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(27392..29203)
                     /gene="edd"
                     /locus_tag="ROH59_002632"
     CDS             complement(27392..29203)
                     /gene="edd"
                     /locus_tag="ROH59_002632"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HDX4805097.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDNNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(29438..30913)
                     /gene="zwf"
                     /locus_tag="ROH59_002633"
     CDS             complement(29438..30913)
                     /gene="zwf"
                     /locus_tag="ROH59_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDX4805098.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            31251..32120
                     /gene="hexR"
                     /locus_tag="ROH59_002634"
                     /gene_synonym="yebK"
     CDS             31251..32120
                     /gene="hexR"
                     /locus_tag="ROH59_002634"
                     /gene_synonym="yebK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HDX4805099.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAALALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGTKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            32248..33690
                     /gene="pyk"
                     /locus_tag="ROH59_002635"
     CDS             32248..33690
                     /gene="pyk"
                     /locus_tag="ROH59_002635"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDX4805100.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQEAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(33822..34793)
                     /gene="lpxM"
                     /locus_tag="ROH59_002636"
                     /gene_synonym="msbB"
     CDS             complement(33822..34793)
                     /gene="lpxM"
                     /locus_tag="ROH59_002636"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HDX4805101.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMVMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(34912..36234)
                     /gene="mepM"
                     /locus_tag="ROH59_002637"
     CDS             complement(34912..36234)
                     /gene="mepM"
                     /locus_tag="ROH59_002637"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HDX4805102.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(36250..37182)
                     /gene="znuA"
                     /locus_tag="ROH59_002638"
     CDS             complement(36250..37182)
                     /gene="znuA"
                     /locus_tag="ROH59_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HDX4805103.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETQVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQV
                     TIAQLEDVKPLLMKSIHDDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLNQLANQYASCLKGD"
     gene            37261..38016
                     /gene="znuC"
                     /locus_tag="ROH59_002639"
     CDS             37261..38016
                     /gene="znuC"
                     /locus_tag="ROH59_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HDX4805104.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            38013..38798
                     /gene="znuB"
                     /locus_tag="ROH59_002640"
     CDS             38013..38798
                     /gene="znuB"
                     /locus_tag="ROH59_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HDX4805105.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAFYDTPAGPSVVLCAALLFIISMMKKQAS"
BASE COUNT         9417 a         9931 c         9534 g        10076 t
ORIGIN      
        1 aacaataaaa taatatattc caacagttgt cttatattct caaaatatgt taaggttgcg
       61 ccctcatttg gggagtagct gatttccaga ttccggaaat gtacgtgtca acatactcgt
      121 tgcaaaacgt ggcacgtacg gactgaacac tttcagtcag gcgagaccat atgcacatca
      181 atcgctatgc ctgcatgaac gcgaaaacca tcgcggcttg ttgttcatgt atgcatgttt
      241 gctgggggcg atgatgtgtt ttatggatac cccggtcagg acgttgtcat gaatatcact
      301 gctactgttc ttcttgcgtt tggtatgtcg atggatgcct ttgctgcatc aatcggtaaa
      361 ggtgccaccc tccataaacc gaaattttct gaagcattgc gaaccggcct tatttttggt
      421 gccgtcgaaa ccctgacgcc gctgatcggc tggggaatgg gcatgttagc cagtcggttt
      481 gtccttgaat ggaaccactg gattgcgttt gtgctgctga tatttctcgg cgggcgaatg
      541 attattgagg gttttcgtgg cgcagatgat gaagatgaag aaccgcgccg tcgacacggt
      601 ttctggctac tggtaaccac cgcgattgcc accagcctgg atgccatggc tgtgggtgtt
      661 ggtcttgctt tcctgcaggt taacattatc gcgaccgcat tggccattgg ttgtgcaacc
      721 ttgattatgt cgacattagg gatgatggtt ggtcgcttta tcggctcaat tattgggaaa
      781 aaagcggaaa ttctcggtgg gctggtactg atcggtattg gcgtccagat cctctggacg
      841 cacttccacg gttaataaga acgctgccag aggtgaatat taaagtccgt ctggcagtcg
      901 aacacttctt ttgctgccag tgcttgccag acttcaggct tcgcacgcca ggcaaacggc
      961 gtcatctgca ataatgcgac ggcttcatca ccgcgaagac gcatcagata acacaactca
     1021 tcactctgct gtaatgtaaa acctttcagt tgttctgcat gaggtgcatg aagatgtact
     1081 tcattgtaaa tcagcccctt cagctccatt aagtgtctcg gtcccggcgt ggcagtaatg
     1141 acccaaccgc cgggcttcac tactcgcact aattcttctg ctttacacgg cgcgtaaata
     1201 cgtattatgg cgtccatact ggtatcggaa aacggcaaac ggtggctgga agcgacacaa
     1261 aaagtgacct gcggatagcg tttcgccgcc gcttttatcg ctaccttcga gacatccagg
     1321 ccaaacgtgg tgatttcggg caacgcatca gcaaatgcgt gtgtgtaata cccttcacca
     1381 cagccaatat ccagcaccgc cgtggccttt tcatcaagcc attcccgcag ttgggcgaca
     1441 attgcatcac gcagcggctg ataatgtccg gcatctaaga atgcgcggcg tgcttgcatc
     1501 atttccgcgc tgtcgcccgg atcacgagac cgtttatgct gaacgggcag cagattgaca
     1561 tacccttctt tcgccatatc aaactgatgt cgctggggac agatatagct gtttttttca
     1621 cgcaaaagag gctgatggca aagtggacag gaaaacgaca tgacaactcc ggcaggatac
     1681 taaaggccgc aagtgtaacg cgaatcatgc ggcgggcaaa tatccgaacg actggagcga
     1741 agataaaaca aagtaaaaag cctcgcattc gacgaggctt tatagcgaga ttgaagcgta
     1801 ttcacacttc agatcagtgg attcgatcag atagctgtta cgttaacagc tgccggacct
     1861 ttctgaccgt cctgaatttc gaactcaacg ttctgacctt cagccagagt tttgaaacca
     1921 ttaccctgga tagcggagaa gtgtacgaac acatctttgc tgccatcagc cggagtaatg
     1981 aagccaaaac ctttagactc gttgaaccac ttaacctgac ctttaatctt tgccatttga
     2041 aaaattcctt agattgtttt cttcgcccgc aggcataaca tagataaaac tgacacatta
     2101 ctgcatgagg caccaatata aggctcggca gagaagcggt attcaacgtc aacgtgttta
     2161 ctcaggactt ctttactgaa aatgccacac ataaacagaa ctgtacctcg tttaacccga
     2221 aatctgttat cacatacaac gttaattatg gcaagccatt tttaaacatg tctcgatcag
     2281 acgcacaaat ctcgatacgt cttccacttt ttttgcacac ttatgcaacg gaatacgcgc
     2341 cgatatatca ttgtgcttaa ccttgccagt tcaggcagat acttaaactg acgtattttc
     2401 taacatagtt caataagttc agttgttcca ggccagtggg agaagttatt acatagtgcg
     2461 tgcaatatca cattttctac tatgcaatga ataaaaagtt atatcacttt ttctcataaa
     2521 acagtcagtt aacgggtatc aattacccca aagagaagtc aatctccaaa ggtattgtaa
     2581 atttaaaata agaaaaattg atgaattagc aaaaaaatca agagagaaac gtttcgctaa
     2641 taaataatac cacacttaat cacaaatccg atgtaaacat cctaataaat taatggggta
     2701 aatatctttt tctgatatcc cgttacgcaa ataaataata tgataattat ttgaagtcag
     2761 accagagttt taatttgaag cagttgcacc atgacagtgc gtataatcag catgaattga
     2821 gtaacccttc aacgacgggg ttactcaaga ttgaggaagg attatcgttc ggcgaccaga
     2881 cgaataatat cttcgtcttc aaccgatttt tgactctcaa cggtcttttt atctgctttc
     2941 tcaggttcgt ttgcttcgca caaacgacgt aacagtgcat tttgacgttt ttgctgatcc
     3001 agcaacgcct caagcagttc aatctgttcg ttagtccgtg aactggcacg attgataaaa
     3061 aaccacaaga tgagcccgat aagaagaacc accaccgata caaccaaaga cgcaatgttc
     3121 atcacgcctg aatttacaac ttcgttcatt tcaccacctc tgagtagagg cgctattcta
     3181 ccactgctgg agaggaagaa aatccagtgc tgaaaaaatg atatcaccac gggataaact
     3241 ggttaatggc acaaattccg ctgaaaaatt gtacatcctg atcgcacatc atgttgaata
     3301 cctgcgccca aagcagcaag caagccaaca ccacgacaac cagagcgacc catcgaaact
     3361 ttttcactcc aatctccgtt tcacctacct tatgtcatta aactagcatg cgttagttaa
     3421 acagcgccta actatgtcga tattcgtgct ttttcagaat gagtcgcttg cttcagcgca
     3481 tattgccgct acgattaagc gaacataaaa agagaagagg ttgtaatgcg attcatcatt
     3541 cgcacagtta tgctgatagc actggtatgg ataggattat tactcagcgg atatggcgtt
     3601 ttgattggaa gcaaagagaa tgccgcggga ttaggtttgc aatgtaccta tctgaccgcc
     3661 agaggcacca gcacggtaca atacctgcac actaaaagtg gttttctggg gataacagat
     3721 tgcccgttgt tacgcaaaag caatattgtg gtcgataatg gttaagggta ataaataacc
     3781 agattctcac tcatgagtaa aatattctta tcgcaagtgc gtttaatata acgccacctt
     3841 caactttatt tttctcatgc taaataaaga acctgtctgt ttgatattca gacaggttct
     3901 tactctcatc agaacggata gtcgtgataa cccatttggg cagaaatttt gcgcgccgcg
     3961 gtatgcaaca ttgcgacata ttcctgtaaa cgctcttcag agaaacgcaa cgtcgggaag
     4021 gagatgctca gaccggcaat gaccacgcca aagcgatcaa ataccggaac cgcaatgcaa
     4081 cgcagtcctt cttcctgctc ttcgttatct tcgccatacc cctgctcgcg cacctggtcc
     4141 agaacgggta ataacgcttc tgtactgatg atggtccgtt cggtactgcg tttatactcc
     4201 acgccctcaa gaatttgcat cacttcatcg cgatcgcgcc atgccagcag taccttacca
     4261 atcgcggtgc tgtacagcgg attacgacgc ccaatccgtg aatacatgcg caaattgtac
     4321 attgagtcaa ttttgtggat gtaaacaata ctgtcttcgt ccagtgcgcc gaggtggata
     4381 gtttctttgg tcaggcggga gatctcacgc atctggatat ctgcgctacg aattaaatcg
     4441 acgttttgca acgcgcgggc gcccagttca aacaatttca gggtcagcga atatttctcc
     4501 gactcccctt cctgcgccac ataacctaag gttttcatgg tctgtaaaaa gcgataaacg
     4561 gtgctttttg acatcatgac gcgctgcgac aactcggtta tccctatttc gcgctcttca
     4621 cccagcgcct gcaaaatgcc aaaaactttt agcacggaag atacagaatc aggctgttta
     4681 tccagatctg cgttagccat ttatcacctc attgcgagtg ttttataaaa atcagaactg
     4741 ttttttatta taatttcgca cctgggtggt cgcaatccat cttttgccgg ttagttacaa
     4801 ttctgcgaca tccaccgtga atatcagtgc tagaatcata cccctgttga ttattcacca
     4861 aagatataaa attcctatgc caaaagttca ggccgacggc ctgccattgc ccctgcgata
     4921 cggtgcgata ttaaccattg tgattggtat ttcgatggct gtccttgacg gcgcaatcgc
     4981 caacgtcgcc ttgccaacaa tcgctacgga ccttcatgcc acgccggcca gttccatctg
     5041 ggtagtgaac gcctatcaaa tcgccattgt catctccctg ctctcgtttt cgtttctggg
     5101 cgatatgttt ggctatcgac gtatttataa atgcggtctg gtcgtttttc tgttgtcttc
     5161 actgttctgc gccctttctg attcgctgca aatgctcacc cttgcgcgtg tcatacaagg
     5221 tttcggcggt gcagcgttga tgagcgttaa taccgcactt atccgcctga tctatccaca
     5281 acgttttctg ggtagaggga tgggcataaa ctcgtttatt gttgccgtct cttctgctgc
     5341 cgggccgaca attgctgcag caatcctctc catcgcatcc tggaaatggt tatttttaat
     5401 caacgtaccg ttgggtatta tcgccctgct tctggcgatg cgttttctgc cacccaatgg
     5461 ttctcgcgcc agtaaacccc gtttcgacct gcccagcgcc gtgatgaacg cgttaacctt
     5521 cggcctgctt attactgcat tgagtggttt cgctcagggg caatcgctga cattgattgg
     5581 tgcggaactg gtggtaatgg ttgtcgttgg tattttcttt attcgccgcc agctttctct
     5641 tcccgtaccg ctgctaccgg tggatttact gcgtatcccg ctgttttcac tttctatttg
     5701 cacatctgtt tgctctttct gcgcacaaat gctggcaatg gtttcccttc ccttttacct
     5761 gcaaaccgtg ctcgggcgta gtgaagtcga aacaggttta cttctgacac cgtggccgtt
     5821 agcaacgatg gttatggctc cactggcagg ctatttgatt gaacgcgtac atgcaggatt
     5881 gctgggtgct ttagggttat tcatcatggc tgcggggctt ttttccctgg ttctgctgcc
     5941 agcgtcacct gcggatatca atattatctg gccgatgatc ttatgtggtg ctggatttgg
     6001 cttgttccag tcacccaata accacaccat tattacctcc gctcctcgcg aacgtagcgg
     6061 tggagccagt ggcatgttag ggacggctcg tcttctgggt cagagtagcg gcgcggctct
     6121 ggtagcgctg atgctaaatc agtttggtga taatggtacg cacgtctcgc tgatagctgc
     6181 ggctattctg gcagtgattg ctgcctgtgt cagtggttta cgtatcactc agccacgatc
     6241 cagggcataa aaaaagcgcg tcgatcagga cgcgcttttt agtatttacg tcatattact
     6301 tcaggtattc acccgtacgc agagcttcaa tacgtttatc cagcggcggg tgggtcatga
     6361 acaactcact gagcgatttc gacttaccgt taatgcagaa agccatcatg ctggttgctt
     6421 cttgcggttc atagctggtt ttcaggcgtt gcagcgcggc aatcattttc tcgcgaccaa
     6481 ccagttttgc tgaacccgca tcagcatgga attcacgatg acgcgagaac cacatggtga
     6541 taatgctcgc cagaatacca aacaccagtt ccagaaccgt tgcaaccgca aagtagatca
     6601 gcgggttgcc gttgctctct tcaccttcat cacggtttcc gcccataaaa cccgcggcaa
     6661 gctgcgccag aatacgggaa ataaagataa cgaaggtgtt caccacgccc tgaatcagcg
     6721 tcatggtgac catatcacca ttggcgatgt ggctgatttc gtgagcaatt accgcctcgg
     6781 cttcatccgg gctcatgttc tgcagcaaac cagtgctgac agcaaccaga gaggcatcac
     6841 ggcgcgcacc agttgcaaaa gcattgatgt ccggcgcatg gtagatagcc acttgcggca
     6901 tagcgatccc cgcctgacga gcctgggttg ctacagtatt gaccagccaa cgttcccttt
     6961 cgttacgcgg ttgctcgatc acttccccgc caacagatcg taatgccatc catttggaca
     7021 tcagaagcga aacgaaggaa ccaccaaaac cgaacagcaa ggccatgatc atcagcccct
     7081 gaacgctgct cgactgtatc cctgtcaggc tcagtaccag cccgaaaacg accattacgg
     7141 ccaggttcgt tagcaggaag agcgcgattc gcatcataat tttcttttta cctcagttta
     7201 acaaaacgca atatgcgata cccacatcgt atgggttacg cgactatttt caagtctgga
     7261 tagtgcgtaa gtcaccagaa agacacaact ttacattttg tagcatctga tttacggcat
     7321 cttgccgctg ttaaaaaatc aggcacaatt tcttgtgcct gatagatatt acttgacggg
     7381 agcgggttgt tccgcgggtc tggctttttc aagcttcgcc agatcgagtg cgatattcac
     7441 cgtctcatcc agataaggat ctggctcctg gtaatctttc ggtagatcat ccagtttctt
     7501 caactccggt ttaccttcgc gtttaaagcg ttcgttcaaa cgcgccagac gcgtcgcatc
     7561 atcttcatta ttctctttct cacgcacagc gtaattcaga gaaacgatat tgcgcttgtc
     7621 cttcatagcg ttgaagcgcg cgatatcctt catgatgttc tggaactcag gatctttcgc
     7681 gatacgcgca ttatgttcct tcagcagctc cggttcaaag gccgttaaat ctcctgattt
     7741 cacataagtc gcggcatcaa tgctatccca cggcagcgcg ttatcttcga atttctcacc
     7801 cgtttccgtt tcttcattac ccgtcggcat gatgatgtct ggcgttacgc ctttacgttg
     7861 cgtactgccg ccgttaacgc gatagaactt ctggatcgtg tactgcacag aacccagcgc
     7921 tggccattca ggacgtaaca tctgatcgta aatacggttc aatgaacggt actgctgaac
     7981 ggtgccttta ccaaacgtcg gttcacccac aaccagggca cgaccgtaat cctgcattgc
     8041 cgcggcaaag atttctgaag ccgaagcact gaagcggtca accagcacca ccagcgggcc
     8101 tttatagaag acctgtccgt cggtgtcgct gtcttcacga accttgccgt tgttatcgcg
     8161 gacctgaaca atcgggccgg atggaatgaa cagaccggag agcgatacgg cttcagtcaa
     8221 cgccccacca ccattgctac gcaggtcgat aatcacactg ctgacattct gtttttccag
     8281 tttctgcagt tgcactttga catcgtctgt caaacccaca tagaagcctg gaatatccag
     8341 cacgccgact ttctctttac cgacggtctt caccgacatt ttaaccgcgc ggtcttcgag
     8401 acgaatacgt tcacgggtca acgttacagt acgcgtcttg gtccctttac cagcaggtaa
     8461 aatttccaga cgaactttac tgcccttagg ccctttaatt aaggccacca catcatcaag
     8521 acgccagcca atcacgtcaa ccatcggctt gcctgtttga ccaacaccga caattttgtc
     8581 accaacgctg atagctttgc tcttcgctgc cggacctcct gccaccatcg aattgataac
     8641 ggtgtagtca tcatccattt gcagcactgc gccaatacct tccagcgaca aactcatttc
     8701 agtgttgaac tgttcggtat tacgcgggga aagatagttg gtatgcgggt cgatttcacg
     8761 tgcaaacgcc gtcattgcca gcgagaaaac atcttcgctg ttggtttgcg ccagacgacg
     8821 aatggcaaat ttgtagcggc gagtcagggt ttcacgaatt tccttatccg tttttcctgt
     8881 cagcttcagg cttaactcgt cgaatttgac tttactgtcc cacagcgcgt tcaactcagc
     8941 ctcgtttttc ggccagggcg ctttgctgcg gtcaaggtta taagtgtcgt tgccggtgaa
     9001 atccatcggc ttttccagta ccgacaaagc gtactggtaa cgttcaaaac ggcgcttttg
     9061 cgccagattg tagagatcgt agaaaacgtc gagtttacct gaacgcagtt catcgcctaa
     9121 ctcagttttc tttttcgcga actgttcaac atcgcttgcc agcagcacat tatggctgta
     9181 atcgagcaga ttcaggtagc ggtcaaagat tttggccgaa aatgcctgat cgaggtcgaa
     9241 ctggcgataa tgagaacggg tgaagcgcga cgttacgcgc tcactcaccg tcgcatgctg
     9301 cgtctcttcc tttaataccg gaatttgatc agcacgcgtg atatcttcta cagcgaaggt
     9361 ctggcctgct attgcaagca ggccagctaa cgcggtaagc ctaaaaaaca tgttcatgcc
     9421 tggcccggcc tccgtttcag aacaccaggt gttctgcgcg cacaatcaaa gacatacccg
     9481 aattcagctg gacgcggacg ccgtctttgg tgatttctaa tacggtggca tccatcgcgt
     9541 tttgacccgc tttcaccttc agggcttgtc cgacagtcag agctgaaatg tcagaaaccg
     9601 gggtgtgctg ttcttcgcga ggtgctttta ctgtttttgg cgctttctct accggctttt
     9661 gcgcacgagg tttacgttca gcgccttctt tgcggcgtgg cgtggtcggg cgtggcttgc
     9721 gttcgcggcg cggtgcgtct tctttctcac cagcagctgc ggcagcttcg cgttttttcg
     9781 cttgctgttc agcacgctgt gcctgaacac gcgctttcgc ttcttcaagc tgcttgcgag
     9841 catgctcgac atgttgctcg tccagctcac cgcatgggtt gccgtcaaga tcaacacgcg
     9901 ttgcgccgga tttaacaccg taaagataac gccagctcga agtgtagaga cgtaaagcgg
     9961 atcgcaattg cgttttgctc aggttcattt ccccggcaac acgatcgacc aaatcctgaa
    10021 aaataccgat tttcagcgga cgcgcttcac cttccgcact gaaacagtgg ggaaaacgtt
    10081 cggccagaaa cgcgattact tctttactgc tattcaactt aggttgattt tccatgaaat
    10141 ttcctgatta caacggacgt agccaacaag cgcaggcatg aacaggcgtc attataatga
    10201 cgctatcagt aaatgctacg ttatccgttg attatcctgc gacgctcgca aagaattttt
    10261 tgtaatccgt cgttgcaagc actttttcaa gctgtgccac aagctgacgt aagccttgct
    10321 cgtcctcgtc tgtaaagcga ccgaagacgg tactatcgat gtcgagaaca ccaataatct
    10381 gatttttcac caccagtggc agaacaattt cagaattact cgccgcatca caggcaatat
    10441 gcccgtcaaa cgcgtgaaca tcctcgatac gctgcacttg attgcgggca accgcagtgc
    10501 cgcatacgcc gcgcccaacg ggtatccgga cacaggcaat tttgccctga aatggtccga
    10561 gcaccagtgt atcgtcctca agcaaataaa aacctgccca gtttacgtca gtgagacgct
    10621 catataacaa cgcactggtg ttcgcaagcg ttgccagaaa actggtttct cccgccatca
    10681 gcgcgttaaa gtcgcgattt aaatccgcgt aaaattctgc tttgttcatt atataatcac
    10741 ttggttgtct tacctggaac tgccagccta ttaaaataag cattaaatgc gttaatgctc
    10801 aagatcattc ccatcatggg ttaagattaa tgttaattct tattacattt ggcacgtcat
    10861 ggctcttaac acaccacaaa ttacgccgac aaagaagata acagtgaggg ctatcggcga
    10921 ggaactgccg cgtggtgatt accaacgttg cccgcaatgt gacatgctgt ttagcctgcc
    10981 cgagataaat tctcatcaaa gtgcctattg tccgcgctgt caggcaaaaa ttcgtgacgg
    11041 gcgcgactgg tcgctaacgc gcctggcggc aatggccttc accatgctgt tgcttatgcc
    11101 gtttgcctgg ggcgaaccgc tgttgcatat ctggctgtta ggcattcgta ttgacgccaa
    11161 cgttatgcaa ggcatctggc aaatgaccaa acagggcgat gcgataacgg gggcgatggt
    11221 ctttttctgc gttatcggtg cccccctcat tctggtgacc tccatagctt atttatggtt
    11281 tggtaaccga ttgggaatga atttacgccc ggtactgctg atgcttgagc ggctgaaaga
    11341 gtgggtgatg ttggatatct acctggtcgg cattggcgtt gcttctataa aggtacagga
    11401 ttatgcccat atccaggcgg gggtcggctt gttctctttt gtggcgttgg tgattttaac
    11461 gacggtgacg ttgtcacatc ttaatgtcga agaactgtgg gagcgatttt atccgcagcg
    11521 ccccgctacg cgaagggacg agaaactccg tgtctgtctt gggtgccatt ttaccggcta
    11581 tcctgatcag cgtggtcgct gcccgcgttg ccatatcccg ctactcctgc gtcgccgtca
    11641 tagtctgcaa aaatgctggg cggcgctgtt agcgtcaatc gttttgttgt tacctgccaa
    11701 cctgttgcct atctctatca tttatctgaa tggtggtcgg caggaagata cgattctttc
    11761 cggaattatg tcgctggcaa gtagcaacat tgcagttgcg ggaatcgtgt ttatcgccag
    11821 tattctggta ccgtttacta aagtgatcgt catgttcact ttactgttga gtattcattt
    11881 taaatgccag caaggtttac gcacacgcat tctgttactg cggatggtga cctggattgg
    11941 tcgctggtcg atgctcgacc tgtttgtcat atctttaacc atgtcgctga ttaatcgcga
    12001 tcagatcctc gcttttacta tgggaccggc tgcgttttat ttcggcgcag cggtaatttt
    12061 gactattctt gctgtggaat ggctggacag ccgcttactt tgggatgcac atgagtcagg
    12121 aaacgcccgc ttcgacgact gaagcgcaga ttaaaaataa acgccgtatc tcacctttct
    12181 ggctgctgcc gttcatcgcg ctaatgattg ctggttggct gatttgggac agttatcagg
    12241 accggggcaa tactgtcacc atcgacttta tgtcggcgga tggtattgtt ccaggccgta
    12301 cgcctgttcg ttatcagggc gttgaagttg gaacagtgca ggatatcagc ctcagcgacg
    12361 atcttcgtaa gattgaagtc aaggtcagca tcaagtccga tatgaaagat gcgctgcgcg
    12421 aagagacaca gttctggttg gtgacgccaa aggcctcgtt ggcaggtgtc tccgggctgg
    12481 acgccctcgt cggtggtaat tatatcggca tgatgccggg taaaggtaaa gagcaggatc
    12541 actttgtcgc actcgacacc caaccgaaat atcggctgga caatggcgat ctgatgatcc
    12601 acctgcaagc ccccgatctc ggttcactga gcagtggttc attggtctat ttccgcaaga
    12661 tcccggtggg taaagtctac gactatgcca tcaatcccaa caagcaaggc gtggtgattg
    12721 atgtcctgat cgagcggcgt tttaccgatc tggtgaaaaa aggtagccgt ttctggaacg
    12781 tttccggcgt tgatgccaac gtcagtatca gtggcgcgaa ggtgaaactg gaaagtctgg
    12841 cggcactggt taacggtgcg attgccttcg attcacctga agagtcgaaa cctgccgaag
    12901 cggaagatac ctttggtctg tatgaagacc tggcccatag ccaacgtggc gtaataataa
    12961 aactggaact gccaggcggt gccggattaa ccgccgactc gacgccgtta atgtatcagg
    13021 ggctggaagt cggacagctg actaaactgg atttaaatcc tggtggtaaa gtcactgggg
    13081 aaatgaccgt tgatcccagc gtcgtcaccc tgcttcgtga aaatacccgc atcgaattac
    13141 gtaatccaaa attatccctt agcgatgcta atctcagtgc cctgctgacc ggcaaaacct
    13201 tcgaactggt gcccggcgat ggcgagccac gtaaggagtt cgtggttgtg ccaggcgaaa
    13261 aagccctgct gcaagagccg gatgttctga cactgaccct gacagcacca gaaagttacg
    13321 gtattgatgc tggtcagccg ctcattcttc acggcgtgca ggtaggccag gttatcgatc
    13381 gtaaactcac cagcaaaggc gtcaccttta ccgtcgccat cgagcctcag catcgcgaac
    13441 tggtaaaagg cgatagcaaa tttgtcgtca acagccgtgt cgacgtgaag gtggggctgg
    13501 atggcgttga gtttctcggt gccagcgcct cagaatggat caatggcgga atacgtattc
    13561 tgccgggcga taaaggcgag atgaaagcca gctatccact gtatgccaat ctggaaaaag
    13621 cgctggagaa cagccttagc gatttaccca ccacaaccgt gagtttgagt gcagagacgc
    13681 tgccggatgt gcaggcagga tcggtagtgc tgtaccgtaa atttgaagtt ggtgaagtta
    13741 ttactgtgcg tccgcgagct aacgcgtttg atatcgatct gcatattaaa ccggagtatc
    13801 gcaaccttct gaccagcaac agcgtgttct gggcagaagg tggggcgaaa gttcagctga
    13861 atggtagtgg cctgaccgta caggcatccc cgctctccag agcattaaag ggggctatta
    13921 gcttcgataa cctcagcggt gccagcgcca gtcagcgtaa aggcgacaag cgtattctgt
    13981 atgcttccga aacagcggcc cgtgcggttg gcgggcaaat tacgcttcac gctttcgatg
    14041 ccggaaaact ggcggtcggg atgccaattc gctatctcgg tattgatatc gggcaaatcc
    14101 agacgctgga tctgattacc gcgcgcaatg aagtacaggc aaaggcggtg ctctatccgg
    14161 aatatgtcca gacctttgct cgcggtggta cgcgcttctc agtggtcaca ccgcaaattt
    14221 cggcagctgg cgttgagcat cttgatacta tcctccagcc gtatatcaac gtcgaaccag
    14281 gccggggcaa tcctcgccgc gactttgaat tacaagaggc caccattact gattcgcgtt
    14341 acctggatgg cttaagcatt attgttgaag cgccggaagc cggttcgtta ggtatcggta
    14401 cacctgtgct gttccgtggt ctggaagtag gtacggttac cggaatgacg ctggggacat
    14461 tgtcagatcg cgtgatgatt gcgatgcgca tcagtaaacg ctatcaacac ctggtgcgta
    14521 acaattccgt cttctggttg gcatcgggtt acagtctgga ctttggtctg acgggcggcg
    14581 tagtgaaaac cggcaccttt aaccagttta tccgtggcgg catcgccttc gccacgcctc
    14641 cgggtacgcc actggcaccg aaagcccagg aaggcaagca cttcctgttg caggaaagtg
    14701 aaccgaaaga gtggcgtgaa tggggaactg cgcttcccaa ataatgccca ctgctccggc
    14761 gtgcctgcgc cggagcgttt atgctaaact gcacgcctgt ttttttgcca gtggtatatg
    14821 ctcgtggccc aacacaccgt ttatttcccg gacgcctttc tgacacaaat gcgcgaagcg
    14881 atgccttcga cgctctcttt tgatgatttt cttgccgcct gtcagcgccc gttgcgccgc
    14941 agcattcgcg ttaatacgct gaaaacctcc gttgctgatt tcctgcaatt aaccgctcct
    15001 tatggctgga cgcttacgcc aattccgtgg tgtgaagaag gtttctggat tgaacgcgac
    15061 aatgaagatg cattgccgtt gggtagtacc gccgagcatt taagcggcct gttttatatt
    15121 caggaagcca gttcaatgtt gcctgttgcc gccttgtttg ctgacggtaa tgcaccacag
    15181 cgggtgatgg atgtcgctgc tgcaccaggt tccaaaacga cgcaaattgc cgcgcggatg
    15241 aataacgaag gggcaatcct tgccaatgag ttttccgcca gtcgggtaaa agtgttacat
    15301 gccaatatca gccgctgtgg catcagtaat gttgcgctca cgcattttga tggccgcgta
    15361 tttggtgcgg cagtgccaga aatgttcgat gccattttgc tggacgctcc ctgctccggc
    15421 gaaggcgtgg tgcgtaaaga tcccgatgcg ctaaaaaact ggtcaccaga aagcaatcag
    15481 gaaatcgcag cgacccaacg ggagctgatc gacagcgcct ttcatgcatt acgtcctggc
    15541 ggtacgctgg tttactcgac ctgtacctta aaccgggaag aaaacgaagc cgtttgcctg
    15601 tggctgaaag agacttaccc cgacgcagta gagtttttac cgcttggcga tctcttccct
    15661 ggtgcaaaca aggcgctgac cgaggaaggc tttttgcatg ttttcccaca aatttacgac
    15721 tgcgaaggct tcttcgttgc tcgtctgcgt aaaactcagg cgatccccgt cttacccgcc
    15781 ccaaaataca aagtgggcaa tttcccgttt agcccagtga aagatcgcga agccggtcaa
    15841 attcgtcagg cggctgcaag tgttggctta aactgggatg aaaacctgcg actctggcag
    15901 cgtgacaaag aactgtggtt gttcccggtg ggcattgaag ccctgatcgg taaagtccga
    15961 ttttctcgct tggggattaa acttgccgaa acgcacaaca aaggttatcg ctggcagcat
    16021 gaggccgtta ttgcccttgc ctcccccgac aatgtgaacg cttttgaact gacaccgcag
    16081 gaagcggagg agtggtatcg cgggcgcgat gtatacccgc atgccgcgcc agtggcggat
    16141 gatgtattgg ttactttcca gcatcagccg attggtttag ccaaacggat tggttcacga
    16201 ctgaaaaaca gctacccgcg tgaactggtg cgcgacggga aactttttac cggtaacgcc
    16261 tgacagcgca caaaaaagcg cactttttga ctggcacatt cgactgcctc aactaggctg
    16321 aaaaatggtg cgatcggact ggtcgtacca caaccggcag ctaaatggag agcacgaaga
    16381 tgaaaaccag tgtgcgcata ggcgcttttg aaatcgacga cggcgaatta cacggcgaat
    16441 cgccgggtga tcgaacgtta accattcctt gtaaatcaga ccccgattta tgtatgcaac
    16501 tggatgcctg ggatgctgaa accagtatcc ctgccctgct aaatggcgaa cactctgtcc
    16561 tttaccgtac ccgttacgat caacaatctg atgcctggat tatgcgtctt gcctgatcca
    16621 aaaagaaccc gtcggcatgg cgggttattt gtccgggtta ttcccccgtt gtaaaatctc
    16681 tcctaaactt aacggtacgg caccacactt cggggatgaa atgttcgcgc tggtactttt
    16741 tgtttgctac ctggatggcg gttgtgaaga tattgttgtg gatgtctaca acacggaaca
    16801 gcagtgtctt tattctatga gcgatcaacg gatccgccat ggcggttgtt ttccgattga
    16861 ggattttata gatggtttct ggcgacctgc acaggagtac ggtgattttt aattattgca
    16921 attgcacaag agtcagttct cccccaaaga cagcaccggt atcaatataa tgcaggttgc
    16981 caatatccac gcgatggcgc aaaggtgtat gaccaaacca gaaatgatca gcacctgcaa
    17041 ttccctgccc tttttggcgt tcacctaatc gcgagcggct ccacaagacc tgatgcaaat
    17101 cgacgtcctt ttgccattca taaacatcat ctggataatc ggcatgagca ataacatgtt
    17161 tgccggtgcg gctgtgtact tcaagaataa agggcaaatg ctgacatttt tccagcgccg
    17221 ttttcgcttg tttctgttga ttatctgcca gcgcaataaa ccagtcgccg ccattcatca
    17281 accataaaga catctgccgg gatgccagcg catccatcgc catctgttca tgattgcctc
    17341 ttaccgcacg aacccaatgt tgttccagta actgcaggca acgtaaactt tgcggcccac
    17401 gatcgataac gtctcccact gagataagta aatctcgcca cggatcaaaa cgacaatgcc
    17461 ataatttgcg gcgcaattgc tcaagacaac cgtgtatatc gcctgaaagc cagatatgtc
    17521 gccattgatg acccgcaatt ctctgataaa cgggcgcagg ctgtttcatc aatattttcc
    17581 tcccgcgcta aagatcacat aatcttaaca agaatgttaa aaaacgctgg actcaaacag
    17641 tagagtgtgt gttatggttg actataaagt cagcgaaggg aatgcttctg gcttttaaca
    17701 gataaaaaga gaccgaacac gattcctgta ttcggtccag ggaaatggct cttgggagag
    17761 agccgtgcgc taaaagttgg cattaatgca ggcttagttg ccttgctctt taagaataga
    17821 tgacgacgcc aggttttcca gtttgcgtgc aaaatggtca ataaaaagcg tggtggtcat
    17881 cagcttaaat attaaaaacc gcccgttctg gtgaaagaac tgaggcggtt ttttattgga
    17941 aatcaaaagg ctattttagg taattaacag agtttttcag ctcgctctat aaacggtgcc
    18001 agactcattt tttcgccggg attgttagga tcatcaatct gaatcaccga aatgggttgg
    18061 gctttagtct tcccactggc aacttccttt tgtgcgatat cgtttaaagg atactgcacg
    18121 agagtacttg ggttaatgac atacaaagca ttacccggtc ggcaagtcag catcacctct
    18181 tcgcgattaa acgcccattt gtctttacct acttcaaaac ggctgacggt aatcacctgc
    18241 ggtgccgcca gcgcagctgc agaactggtg agtaacagaa acgccagaat actttttttc
    18301 atcattttcg taatccatca aaaaggttcg agagtcgcaa gcaggctgat gatcaccagc
    18361 actaccgcac ctatcgccca ttcgagttta gtcatccaga caaaccaggg agccgcacga
    18421 tcttcatcct gcctcatgcg cggtacaaga acataacgat tagccagcgc gatgaccacc
    18481 ataatcatca ccaggatggc tttgagcaat aagagttggc cccagtgagt cgtaagcgtg
    18541 gggggaaatc cggtaatcaa caatgcatta agcacgccgc ttgccagtac gccgatcacc
    18601 gcaaaatgcc cgcaccagga aaaacgcatc agcgcctgaa tagcctggtg tcgccaacgg
    18661 cctttgatga gttgcataca ccagagcacc ggcagtaatc ccccaaacca cgccgccgca
    18721 cagatcaggt gaattgcatg attagtctga tggattttcg ccgttacccc ttcattcagc
    18781 gtcgcatgac cgactcccgc cagcagaata aattgcgcgg tagtgagcat aaatagcaaa
    18841 cgtggcatat tctgcggttg cataagggcg acgatcaatg ttacgagggc gagaacaatt
    18901 tgccataacc agacgccacc aaactgcgtt tgcaaaacag ccagccaaat gtttggcgaa
    18961 aatacatctg accatcccgt tcccatcaac ccgccctgaa cggcgagcat tgcagtggca
    19021 ctgatcaaac tccagacggc agcgtgctgt tgtaaacgca gaaaacgctt cgtcagcaag
    19081 cgacgaatcg ttaagggggc cagccaggca ccgtacattg cgaagccaaa aaccagcatc
    19141 agcgaggtga aatggataaa tcgcagcgcg atccaggtaa acgccagcat gatttatttc
    19201 acgctaaagg tgtaatgtcc tttcgtttta tgcccatcca ccgaaacaac atgccagtca
    19261 acggtgtagg ttccgggttt cagcgaatcg gccagtggaa caatcagttg cttttggtcc
    19321 tgctcattac gcttcgccgg taatgtttta atattttcgt tttttggccc cgtgattttt
    19381 gcgccactga atcctgtttc aacgccttcc gagaagttta aagtgattgc ctgcggagct
    19441 gctgtcactt gtgcatttgc cgcaggatac tgatgcgtta aatgcgcatg tgcccagacg
    19501 gaaggtgtca ccaacgaagt ggtcaggatt gccagcgcgt agcgaaggga gcgtgcagtt
    19561 gaagccatat tatctattcc tttttgtaat aactttttta cagagcataa ccttgtctaa
    19621 tgtctgagtc gaggatcatc aattccggct tgccatcaag gctcactctt agtaactttt
    19681 gcccgcgaat gatgaggaga ttaagaatgc tgaagaatct ggctaaactg gatcaaacag
    19741 aaatggataa agtgaatgtc gatttggcgg cggcaggggt ggcatttaaa gaacgctaca
    19801 atatgccagt gatcgctgaa gcggttgaac gtgaacagcc tgaacatttg cgcagctggt
    19861 ttcgcgagcg gcttatcgcc caccgtttgg cttcggtcaa tctgtcacgt ttaccttacg
    19921 agcccaaact taaataaaac ttatacatag ttacactttc ttacataatg cctgctaaat
    19981 tatgagtatt ttctaaaccg cccccataat ttgcagtcat tttgaaaagg aagtcattat
    20041 gtcgttctgg aaagttgcag cagcgcaata tgagcctcgt aaaacctcac tcaccgaaca
    20101 ggtagctcat catctggagt ttgtgagggc cgccgccagg caacaatgtc agctgttagt
    20161 ttttccatcg ctttctttac tggggtgtga ttattcgcga cgtgcccttc ctgccccacc
    20221 cgatctctcg ctattagacc cgctttgtta tgccgcaacg acctggcgaa tgaccatcat
    20281 tgccggcctt cccgttgaat ataacgatcg ctttattcgt ggaattgcgg tattcgcacc
    20341 gtggcgaaaa acgccaggga tctaccatca gagttatggt gcatgtctgg gccgtcgttc
    20401 cagaaccatc acggtggtcg atgaacaacc gcaaggtatg gatatggacc cgacctgttc
    20461 actgtttacg acagggcaat gtctgggaga acccgacctg ctggcgtcgg cccgtcgctt
    20521 acaatttttt tcacatcagt actcgattgc tgtgctgatg gcaaatgccc gtggtaacag
    20581 tgcactatgg gatgaacatg gtcgtctcat cgttcgcgcc gatcgtggtt cattattgtt
    20641 agtcggtcag cgttcatcac agggttggca aggcgatatc attccattac gctaggcttt
    20701 ttcggcctgg agcatgccat gttgcgcatt atcgatacag aaacctgcgg tttgcaggga
    20761 gggatcgttg agattgcctc tgttgatgtc attgacggaa aaatcgtcaa tcccatgagc
    20821 cacctggtgc gtcccgatcg tcctattagt ccacaggcga tggcgattca tcgcatcacc
    20881 gaagccatgg tcgccgataa accgtggatt gaagatgtga tcccgcacta ttacggtagt
    20941 gaatggtatg tcgcgcataa cgccagcttt gaccgccgcg tactgcctga aatgcccggt
    21001 gagtggattt gcactatgaa actggcccgt cgtttgtggc cagggatcaa gtacagcaat
    21061 atggcgttat ataaaacacg gaagctcaat gtacagacgc cgccgggcct gcatcatcac
    21121 cgcgcgttgt atgactgtta tatcaccgct gcgttgctta tcgatattat gaacacctcc
    21181 ggctggacgg cagaacagat ggccgatatc accggacgtc catcgttgat gacgactttc
    21241 acctttggca aataccgtgg caaagcggtt tccgacgttg ccgaacgcga tccgggctat
    21301 ctgcgctggt tatttaataa cctggacagc atgagcccgg agctgcgttt aacactgaaa
    21361 cattatctgg aaaatactta atccgcaggc gtagcgggta atgttccctg cgccagcgcg
    21421 accagaaaag catattccat cgctacgcct tcgtacgatt taaagcgacc agatttaccg
    21481 ccatggcctg agtccatgtc ggtacagagc aataaaagat ggttatcggt tttcagctcg
    21541 cgcaatttag cgacccattt tgccggttcc caatattgca cctgagaatc gtgtaaaccg
    21601 gtcgttacca gtaaatgcgg ataagcctgt gcggtgacgt tgtcatacgg gctgtagctt
    21661 ttcatatact cgtaatattg cggatcctgc ggattccccc actcttcaaa ttcgccggtg
    21721 gtaagaggaa ttgattcatc cagcattgtt gttacaacat caacaaacgg cacctgggcg
    21781 ataacgccgt ggaacaattc cgggcgttga ttaatcgcaa cgcccatcaa catacccccc
    21841 gcactcccgc ccatcgcata acagagcgaa ggagagccat agcccagttt taacaatgca
    21901 tcgcaggcat caagataatc attaaacgta tttttcttct tcagaaattt accgtcctcg
    21961 taccattgtt gccccagctc accgccgcca cgaacatgga caatggcgta gacaaatcca
    22021 cgatccaaca aactcaagcg gctaaaactg aaatcggcat caatacttgc gccgtaagaa
    22081 ccgtagccat acaccagcag cgggttgtgt cctttgcgaa aatgtttgcg atgatagacc
    22141 agcgaaaccg gaacttcgac gccatcacgg gcgactatcc acaggtgttc actgcggtaa
    22201 ttcgccgcat caaaaccagg aacttccgtt tgttttaata cacgacgctc accggtatcc
    22261 atatccagtt caaacaaagt atctggtgtg gtcatggacg aataaccata acgcaatcgc
    22321 gcggtttcag gttctggatt gtaggcaatc caggtcacat aggccggatc atcaaaggca
    22381 atgccaatga cttcccgggt cttgcggtta atttgccgca aactggttaa cccgcgctga
    22441 cgctcttcaa ccaccagcca gtcggtaaac agcgtaaacc cttccagcat aatgttatca
    22501 cgtggcggaa ttaactcttc ccactgttgc tcatcacgca tacgggtacg gtataagcca
    22561 aagtttttac cgtggcggtt ggaacgcaga taaaaccgat gctggtagtg atcaaggctg
    22621 tattcgtgat ctttgcggcg cggcagaaaa acaaacggct cggcatcggc tatttccgcg
    22681 tccagcaggc gaacttcact ggtggtggcg ctggccagat gaatgactac atagtgcttc
    22741 gaggtcgttt tatgcaggct gacgtaatag gtatcgtctt tttcttcgta gatcagttta
    22801 tcctgcgatg ctggcgtacc gatggcgtga cgccagacct gataaggaag cagcgtcacc
    22861 ggatgcttgc gaacatagta gaaagtccag gaatcatttg cccagacaaa gctggggtca
    22921 acgttatcca gcagttccgg ataccagtta cctgtttcca gattacgaaa acgaatgccg
    22981 tactggcgtc gggaaagaaa atcttctgcc agtgccataa tggtgttatc gggcgtaatc
    23041 gccattccgc ccatcgaata aaactcacta tgagccgcgc gcttgttggc atcgagcaat
    23101 gtttcccact catcccactc ttcgctgaac gccgattgac gctggtagat agcatattca
    23161 cagcctggtt cataaatatg ccgatagcgg tagccatttt ttatgtaggg cgcagaaact
    23221 tctctttgcg gaatgcggtc gatgatttcc tttaagatgc gatcctgcaa ggcttgttgc
    23281 gaggccatca cccgatgacc gtaactattt tcttgttgca gatagtccag gacttccggc
    23341 tgagaacgcg tatcgtcccg cagccagtag taattatcga tgcgcgtatc gccatgaagc
    23401 gtcatggcgt ggggaatgcg ggcggctttt ggtagcatgt tattgttctt tctggttgaa
    23461 acatcttata agggtggcaa aactcaccgg ggatgcaagc gaaacagggt agtcattgct
    23521 tagatgatga caggtaatgg cgcggatatc gactgttatg cagacagaga aaatcagcct
    23581 gttcaaatgg ctgtgcggtt ctggataacc cgaaatagtc aacttcaggc tatccagaga
    23641 gcggaattac tccgccaaag tacgtttttg ctgttcgaga tcgcgttcaa tgccttcacg
    23701 aacgtcctgg gggattttca gcgcatcacc cagtgcattc aggtaactgc gttccataaa
    23761 atggtcaata tcaatagccg cgcagctcag gaaatagatt tccagcgcct cttcttcatt
    23821 gcggaccccg gtagccaggc gttgtggatc cagcggttgt tcgattgcct gctcaatgag
    23881 tacacgcccc ttctcttcca caccggcttc acgcaattgc aggtcgattg ccgcacgttc
    23941 tttggcatca atatgaccat cacttttagc ggcaaagacc agcgcaagga tcaaacgttc
    24001 cgtacgctca tccagcggcg tactttgcgc gccaaactgc ggttcgtcct gatgcgccgc
    24061 gcgaatttta tctttgtatt tattccacag caccgtaccc gctaccgctc cgccgccaac
    24121 cagtaacgcg tttgtgccat atttcgtaag aagtttacgt gctgatttat ttgcgaccag
    24181 cagcccagcc agtccgccta atgcgccagg cactaaaagt ttgcccaatc cctgatccgc
    24241 agacgaggag gtagaagaac ggctttgccc aagcagggat tgcagttgat ttaaccagtt
    24301 agccatattt gctcctcaat aaccattttt agtgcctgta gcatagcgga tgaggatgtc
    24361 agaaaatgta tatcgagaca aaagatgcgc aaataagcgg ggcggtaggc cgttattcaa
    24421 agaaattcgc gccaggtaag gtgttcactg tatataaggt gataagggta ttttaggtga
    24481 aagtagtttg acattttgag tggaactgtt tgatgctgat tgcccggttc gacgctactg
    24541 cgtcttctca ggcctacgat tgtgttgcgt tgtagggcgg acaaggcacc cgcgccgcat
    24601 ccgccaacgg tcaatcgaat tatcagaagc cattaacgcc gctgatattc cgccattccc
    24661 gctttgcagt ccacgctgac ctggtaatga atatcggcac ttttaccacg cacggttagc
    24721 ggtactgacc atttatcatc tttcccctga atgtcctgca aactgaccca tgccacggga
    24781 tcggcctgac cgacaatttt ttgatcatca gcccagcgcg ccacgcgatt ttgttggtaa
    24841 tcacgtttta cgctcgcggc aattccggca gcatccagac cttcacactt tgggaaagtg
    24901 accgacttgc tggtttcatt attggcagcg aaaactgatg cgcaggcaga aaccaacaac
    24961 agccctaaaa acgcccctct ttttttcatg tttttctcca tagcacaatg attcaggaga
    25021 aagcatggta caaattgtca ggagcgcaag ttgcttcagg ccgcgtgtga ggcatcttcc
    25081 tcttcggatt cagcaccgac gacctgtggg gacggtaatt tgccggtttt cagaatggtg
    25141 ctcagcacat ctttttgttc tgccagccat agcgaaaggg cttcacgttg ctcgtcttcc
    25201 atttgcactg gagaatttgt cagccaggtg tcaagcagat cggccgtatc aagcatcttg
    25261 tcataagcat cggcttcctt tttgctggta aacgacattt tctcttcgcc ctcacgaatg
    25321 actacgtatt taacttcaac cgccatttgc agcctctcat aataactgtg gttttataca
    25381 gtatatttct tttcagttgg gaaatcaaca tcagcaataa agacacacgc aaacgttttc
    25441 gtttatactg cgcgcggaat taatcagggg atattcgtta tgacgttatt aggcactgcg
    25501 ctgcgtccgg cagcaactcg cgtgatgtta ttaggctccg gtgaactggg taaagaagtg
    25561 gcaatcgagt gtcagcgtct cggcgtagag gtgattgccg tcgatcgcta tgccgacgca
    25621 ccagccatgc atgtcgcgca tcgctcccat gtcattaata tgcttgatgg tgatgcatta
    25681 cgccgtgtgg ttgaactgga aaaaccacat tatatcgtgc cggagatcga agctattgcc
    25741 accgatatgc tgatccaact tgaagaggaa ggactgaatg ttgtcccctg cgctcgcgca
    25801 acgaaattaa cgatgaatcg cgagggtatc cgtcgcctgg cggcagaaga gctgcagctg
    25861 cccacttcca cttatcgttt tgccgatagc gaaaaccttt tccgcgaagc ggttgccgcc
    25921 attggctacc cctgtattgt taaaccggtg atgagttctt ccggtaaagg gcagacgttt
    25981 attcgttctg cagagcaact tgctcatgca tgggagtacg ctcagcaagg tggtcgcgcc
    26041 ggagcgggcc gcgtaattgt tgaaggcgtc gttaagtttg acttcgaaat taccctgcta
    26101 accgtcagtg cggtggatgg cgtccatttc tgtgcaccgg taggtcatcg ccaggaagat
    26161 ggcgactatc gtgaatcctg gcaaccacag caaatgagcc cgcttgccct tgaacgtgcg
    26221 caggagattg cccgtaaagt ggtgctggca cttggcggtt atgggctgtt tggtgtcgag
    26281 ctgtttgtct gtggtgatga ggtgattttc agtgaagtct cccctcgccc gcatgacacc
    26341 gggatggtga cgctaatttc tcaggatctc tcggagtttg ccctgcatgt acgtgccttc
    26401 ctcggacttc cggttggcgg gatccgccag tatggtcctg ctgcttctgc cgttatcctg
    26461 ccgcaactga ccagtcagaa tgtcacgttt gataatgtgc agaatgccgt aggcgcagat
    26521 ttgcagattc gtttatttgg taagccggaa attgatggca gccgtcgtct gggggtagca
    26581 ctggctactg cagagagtgt tgttgacgcc attgaacgcg cgaagcacgc cgccggacag
    26641 gtaaaagtac agggttaaac ccggcaaaaa aacgctacaa aaatgcccga tcctcgatcg
    26701 ggcattttga cttttacagc ttagcgcctt ctacagcttc acgcgccagc ttagtaatgc
    26761 ggtcgtaatc gcccgcttcc agcgcatctg ccggaaccag ccaggaacca ccgatgcaca
    26821 gcacgctttt cagcgccagg tagtcacggt agttagccgg agaaatacca cctgtcgggc
    26881 agaaacggac ctgggagaac ggacccgcga tcgcctgcag ggctttcaca ccgccgttag
    26941 cttcagccgg gaagaatttg aactctttca aaccgtagtc catacccagc atcagttcgg
    27001 aaacagtgct gatccccgga atcagaggaa tagtcccttc ggtagcagct ttcagcagcg
    27061 gctcggtcag acccgggcta attgcaaact gtgcacctgc ttcagtgact tctgccagct
    27121 gctgtggatt cagcaccgta ccggcaccca caatcgcttc aggcacttct ttggcgatag
    27181 cacggatagc gtcaactgcg cactcggtac gcagagtcac ttccagaacg cgcaccccac
    27241 cagcaaccaa cgcttttgct atcggcaccg cgtgttccag tttttttacc acgataaccg
    27301 gtacaaccgg gccggtggtc aggattgatt ctgcacttgt tttccagttt ttcatcagag
    27361 ttttctctcg cctgattaca aatttgtcgt cttaaaaagt gatacaggtt gcgccctgtt
    27421 cggcaccgga cagtttttca cgcaaggcgc tgaataattc acgtcctgtt cccacgcgtg
    27481 acgcgctcag gtcaggaatg tgcggttcgc gagcagccag ttccgcttcg tctaccagca
    27541 gcgtcagttc gcctgtctgt ccattcacac gaatgatgtc cccgtcgcgc acttttgcca
    27601 gcagcccgcc atcgtaggcc tctggtgtta cgtggatagc tgacggcact ttacctgaag
    27661 cgccggagag tcgtccatcg gtaactaacg caattttgaa acaccggtcc aataatacac
    27721 caagtggcgg catgagttta tgtaattctg gcattccgtt cgcttttggc ccctgatgac
    27781 ggacaacaac gacacaatcg cggtccagta aacccgcttc aaaggccggc ataacgtcat
    27841 gctggctttc aaaaacaacc gctggcgctt caatcacctg gttctctacc ggcacggcag
    27901 aggttttcat aaccgctcgc cccaggttac cgcttaacac ttttgtccca ccatgatgag
    27961 agaaaggttg ttcgaaggac gcgatcacat tgttgtcgag tgatttttct gccccttccc
    28021 gccagtccag ttcaccatta ttcagccatg gttcaagggt ataacgagac agaccaaagc
    28081 ctgccaccgt attgacatct tcatgcagca ggcctgcttt gagcagttca cgtaccagaa
    28141 ccggtacgcc acctgccgcc tggaagtggt taatatcggc cggaccgttc gggtagagac
    28201 gtgccatcag cggtacaaca tcagaaaggt cagagaagtc atcccagtta atctgaatac
    28261 cggctgcgcg cgccatcgcc actaggtgca tggtgtggtt agtggaacca ccggtcgcca
    28321 gcagtgcaac gataccgttc accaccactt tctcatcgat catcttaccg atcggcatcc
    28381 attcattacc attaccggtc atgcgcgtaa cctggcgcgc agctgcagcg gtcaaagcat
    28441 cgcgcagcgg agaatccgga tgaacaaaag aagagcctgg caactgcatc cccataaact
    28501 ccaccaccat ctggttggtg ttggcagtac cgtagaaagt acatgttccc ggcgcatgat
    28561 aagacgcggc ttctgactcc agtaatgcca tgcggtccac tttaccttcg gcataaagct
    28621 ggcgaatacg cactttttct ttatttggca aaccgcttgc catcggtcca gacggcacaa
    28681 acaccgcagg caaatgacca aacgacaggg ctgccatggt cagacctggg acaatcttgt
    28741 cgcacacacc gagaaacaga gcaccatcaa acatgttatg ggacagcccc accgccgcag
    28801 acatcgcaat cacttcgcgg cttaacagcg acaattccat tccatcctgc ccctgggtga
    28861 caccatcaca catcgccgga acaccgcccg caacctgacc aaccgcattc gcttcatgca
    28921 gggctttacg aatgatttct ggatagtgtt cataaggctg gtgagcggag agcatgtcgt
    28981 tataggaggt gatgatggcg atattgttac gcaacatgct tttcaaagag gctttgtctt
    29041 ctggctggca ggcagcgaaa ccgtgtgcca ggttaccgca tgccaactgc gaacgatgaa
    29101 cggtcgaagt tttcgcttgt tctatccggg cgaggtaagc agagcgagtc tcgcgcgaac
    29161 gttcaatgat tcgatttgtt acgcgtaaca attgtgggtt cataaaggct cctgaaattg
    29221 agttgtcaga gcaggatgat tcacaacgcg tttcatacat ggaaattatg attgaaacgc
    29281 ctgtaaccgg agctcatagg gcaaaaacgt ttcagtcagt gtaataaaaa aagcctcgtg
    29341 ggtgaatccg cacgaggcct gaaagtgtaa aaattgttct acaatctgtg caagatcatg
    29401 ttaccggtaa aataaccata aaggatgagc gcagatatta ctcaaactca ttccaggaac
    29461 gaccatcacg ggtaatcatc gccactgagg caacgggtcc ccaggttccg gcctgatacg
    29521 gtttcggcgc atcattgtcc atcgcccacg cctcagtaat ggagtctacc catttccagg
    29581 cttcttccac ttcgtcgcga cgtacaaaca gtgcctgaat accacgcatg gtttccagca
    29641 gcaaacgttc ataggcatcc gccagatgcg tctgattaaa ggtttctgaa tagctcagat
    29701 ccagcttggt gatttgcagg ttatgtttgt ggtcaaggcc aggaacttta ttcagtacct
    29761 ggatatccac gccttcatca ggttgcagac ggatagtcag tttattttgc ggtagatcct
    29821 gccacgactc tttaaacaga ttcagttcag gtgttttgaa atagaccacg acttcagaac
    29881 atttggtcgg cagacgttta ccagtacgca ggtagaatgg cacaccggcc cagcgccagt
    29941 tatcaatgtc gacgcggatc gccacgaagg tttctgtatt gctgctcttg ttcgcgccct
    30001 cttcttccag atagcccggc acttttttgc cctgagcgaa gcccgcagta tattgcccgc
    30061 gtacggtttt ttcgcgcaca ttggagcggt cgatgcggcg cagagacttc agtactttca
    30121 ctttttcatc gcggatgctg tctgcgctca ggtcagacgg cggagacatc gcaatcatgc
    30181 aaagaatttg cagcaggtgg ttctggatca tgtcgcgcat ctgaccggct ttatcaaaat
    30241 agccccagcg cccttcgatc cccacttctt ctgccacggt aatctcaaca tgatcaatgg
    30301 tgcgattgtc ccagttgttc acaaacagag agttagcaaa acgcagcgcc aacaggttca
    30361 gcactgtttc tttaccaaga tagtggtcga tacggtaaac ctggcactcc tcgaagtatt
    30421 cgccaacctg atcgttgatt tcctgcgagg tcgccagcga cgtccccagc ggtttttcca
    30481 tgactacgcg tgccggttta gcattcagtt ttgcctcacc aagccctttg caaattgcgc
    30541 caaaagtgct gggcggcatg gcaaagtagt taatggtgat acgatttttt tgatccagca
    30601 tcgcgccgag acggctgaat gcagcagtgt cattgacatc aagattacaa aaatccagac
    30661 gtgcactcag ggtgtcccat aaaccttcat caatggtttc tttcatgaaa gtttcgagcg
    30721 cctcgcggac aactttggta taagccgctt tatcccagtc agcacgccct acgccgataa
    30781 tccgggtgtc cgggttgagc tgaccggctt tttccagttg atacagggaa ggcagcaatt
    30841 tacgacgcgc aaggtcgcct ttcgcgccga aaatgaccag gtcacaggcc tgggctgttt
    30901 gcgttaccgc catgtcattc tccttaagtt aactaacccg gtacttaagc cagggtatac
    30961 ttgtaatttt cttacggtgc actgtactgc ttttacgagc ttgcgaaaac tgtaaacgct
    31021 tatccacccg tgcgattacg gtaaaagcgc gcaaagtgcg gcaaaactga taaaaaaatc
    31081 atcgttttcc attgggtaaa aatctgacac tgatcatgtt atgaaaaaaa ataacaactt
    31141 ttttatctgc ttttgtcatt aacacagcac acaggcgtaa tatctgacaa aactgcattt
    31201 cgatttcttt cagagcggaa atcgtcatta cccgtgagtc tctttacatc atgaatatgc
    31261 tggaaaaaat ccagtctcag ctggaacatt tgagcaaatc tgagcgcaaa gttgccgagg
    31321 tcattctggc ttcgcccgat aacgcgatcc attcgagtat tgctgctctg gcgctggaag
    31381 ccaatgttag cgaaccgacg gtgaatcgtt tctgtcgcag catggacaca cgcggttttc
    31441 ctgattttaa acttcatctg gcacaaagtc tggcgaatgg cactccctat gttaatcgca
    31501 acgtcaatga agatgacagc gttgaatcat acacggggaa aatatttgag tccgcaatgg
    31561 caacgctcga tcatgtccgt cattcactgg ataaatctgc catcaaccgc gccgtcgact
    31621 tgctcactca ggcaaaaaaa atcgcctttt tcggattagg ttcttcagcc gccgttgccc
    31681 acgatgcgat gaataagttc tttcgtttta atgttccggt ggtgtactcc gatgatatcg
    31741 tgctgcaacg catgagttgt atgaattgta gcgacggaga cgtggtggtg ctgatttctc
    31801 acacgggaag aacaaaaaat ctggtcgagc tggcgcagct ggcacgcgaa aacgacgcta
    31861 tggtaattgc cctcacctct gcgggtaccc cactcgcccg ggaagcaacg ctggcaatta
    31921 ccctcgacgt accggaagat actgacattt atatgcccat ggtttctcga cttgcacagc
    31981 tgaccgtgat agatgtgctg gcgacaggat ttactttgcg gcgcggtaca aaattcagag
    32041 ataacttgaa gcgggtcaag gaagcgctga aggaatcgcg ttttgataag cagttactta
    32101 atttaagtga cgatcgctaa aaacgactgt cactgtccta atcttatacg acatccgaat
    32161 gagattaatt tatcgccatc acggcgttat ttcattcgga tttcatgttc aagcaacacc
    32221 tggttgtttc agtcaacgga gtattacatg tccagaaggc ttcgcagaac taaaatcgtt
    32281 accacgttag gcccggcaac agatcgcgat aataaccttg aaaaagttat cgcggcgggt
    32341 gccaacgttg tacgtatgaa tttttctcac ggctcgcctg aagatcacaa aatgcgcgcg
    32401 gataaagttc gtgagattgc cgcaaaactg gggcgtcatg tggctattct gggtgacctc
    32461 caggggccca aaatccgtgt atccaccttt aaagaaggca aagttttcct caatattggg
    32521 gataaattcc tgctcgacgc caacctgggt aaaggtgaag gcgacaaaga aaaagtcggt
    32581 atcgactaca aaggcctgcc tgctgacgtt gtgcctggtg acatcctgct gctggacgat
    32641 ggtcgcgtcc agttaaaagt actggaagtc cagggcatga aagtgttcac cgaagtgacc
    32701 gtcggtggtc ccctctccaa caataaaggt atcaacaaac ttggcggcgg tttgtcggct
    32761 gaagcgctga ccgaaaaaga caaagcagac attaagactg cggcgttgat tggcgtagat
    32821 tacctggctg tctccttccc acgctgcggc gaagatctga actatgcccg tcgtctggca
    32881 cgcgatgcag gatgtgatgc gaaaattgtt gccaaggttg aacgtgcgga agccgtttgc
    32941 agccaggagg caatggatga catcatcctc gcctctgacg tggtaatggt tgctcgcggc
    33001 gacctcggtg tggaaattgg cgatccggaa ctggtcggca ttcagaaagc gttgatccgt
    33061 cgtgcacgtc agctaaaccg cgcggtaatc acggcgaccc agatgatgga atcaatgatt
    33121 actaacccga tgccgacgcg tgcagaagtc atggacgtag caaacgccgt tctggatggt
    33181 actgacgctg tgatgctgtc ggcagaaact gctgctggtc aatacccgtc agaaactgtt
    33241 gcagccatgg cgcgcgtttg cctgggggcg gaaaaaatcc cgagcatcaa cgtttctaaa
    33301 caccgtctgg acgttcagtt cgacaatgtg gaagaagcca ttgccatgtc agcaatgtac
    33361 gcggctaacc acctgaaagg cgttacggcg atcatcacca tgaccgaatc gggtcgtacc
    33421 gcgctgatga cctcccgtat cagctctggt ctgccaattt tcgccatgtc acgacatgaa
    33481 cgtacgctga acctgactgc tctctatcgc ggcgttacgc cggtgcactt tgatagcgct
    33541 aatgacggcg tagcagctgc cagcgaagcg gttaatctgc tgcgtgataa aggttacttg
    33601 atgtctggtg acctggtgat tgtcacccag ggcgacgtga tgagtaccgt gggttctact
    33661 aataccacgc gtattttaac ggtagagtaa gtacgttgcc ggatgcggcg aaaacgcctc
    33721 atccggccta cagttcaatg ataattcaac agatttcgaa tcttctgaag caaacttgaa
    33781 cttatcatca gtcgaaggcc tctcctcgcg agaggcattt tttatttgat gggataaaga
    33841 tctttgcgct tatacggttg gatttcgccc ggtttgcgag ttttcagcaa ttttaatatc
    33901 caggtgtatt gttctggtcg cggaccaaca aaaatctcga cttcttcatt catccgccgc
    33961 gcaatcgtat gatcatccgc ctctaacaga tcatccatcg gtgggcgcac ctgaatcgtc
    34021 agacgatgcg tcttgccatc ataaatcgga aacagcggta caacgcgcgc acggcacact
    34081 ttcatcaaac gaccaatcgc gggcaacgtc gctttatagg tggcaaagaa atcaacaaat
    34141 tcgctgtgtt ctgggccatg atcctgatcg ggtaaataat atccccagta accctgacgt
    34201 accgactgga tgaatggttt aataccatca tttctcgcat gcagacgacc accaaagcga
    34261 cggcgcaccg tgttccagac ataatcaaaa accgggttgc cctgattatg gaacatcgct
    34321 gccattttct gcccttgcga ggccatcagc atggcaggaa tatcgacggc ccaaccgtgc
    34381 ggcaccagaa aaatcacttt ctcgttatta cgccgcatct cttcgatgat ctccagccct
    34441 tgccagtcaa cgcgcggctg aattttctcc ggcccgcgta ttgccaactc agccatcatt
    34501 accatcgctt gcggcgcggt ggcaaacatc tcatctacaa tcgcttcgcg ttcagcttca
    34561 ctacgttctg gaaagcagag cgacagattg attaacgcac gacggcgtga gctttttccc
    34621 agtcgtccgg caaaacgtcc cagccgtgcc agaatgggat cacggaactt tggcggcgtt
    34681 aaagcgatac ccgccatcgc tgctacgccc agccatgctc cccagtagcg cgggtggcga
    34741 aaggatttat caaactcagg aatgtattcg ctattatttt ttttcgtttc catgcttttc
    34801 cagtttcgga taaggcaaaa atcaatctgg tgatagtgta gcggcgcaac ttgccccgca
    34861 ccaaataaaa aagccggtac tgactgcgta ccggctgcga atggatgtta attaatcaaa
    34921 ccgtagctgc ggcacaatct ctttggcctg tgccaggaat tcgcgacgat cggagccggt
    34981 cagcccttcg gtacgcggca gttttgccgt cagcgggttt acggcctgct ggtttatcca
    35041 tacttcatag tgcagatgcg gcccggttga acgtccggta ttaccggaaa gcgcgatacg
    35101 gtcgccacgt ttcaccttct gtcccggttt caccaggatc ttgcgcaagt gcatataacg
    35161 cgtggtgtag ctgcgaccat gacgaatagc cacataataa cctgctgcgc cactacgttt
    35221 ggcaaccacc acttcaccgt cacccactga aagcactggc gtaccttgtg gcatggcaaa
    35281 atcaacacct ctgtgtggcg caacgcgacc ggtcaccgga ttagtacgac gcgggttaaa
    35341 gttagatgag atacggaact gtttcgccgt cgggaatcgc aagaatcctt tcgccagacc
    35401 agtaccgtta cgatcataga atttgccatc ttcagcgcgg attgcataat aatctttacc
    35461 ttctgaacgc aaacgtacgc ccagcagctg gctttgctca cgtttaccat caagcatttc
    35521 tcgtgacatt aacaccgcaa attcatcgcc ttttttcagt ttgcggaaat ccatttgcca
    35581 ctgcatggct ttaatcactg cgctcacttc ggcgctggtt aaaccggcgt ttctggcgct
    35641 ggcaacaaag cttcccccga cggtaccttt cagcagattg ttgacccact ctccttgctg
    35701 catttcgctg gtcattttaa aaccgttagc ggcagtacgg tcataggttc gggtttcacg
    35761 acgagacact tcccaggtga ggcgctgcag ttcgccgtcc gcggttaatg tccaggagag
    35821 ttgttgaccg attttcaggt tacgcaattc tttgtcggca gcagccagtt gggtgatatc
    35881 acccatatca ataccatact gattgagaat gctgcttagc gtatcgccag tggaaacaac
    35941 atattcatgc acgcccgctt caccggcgat tttgtcatcc agttcgtcct ggggaatggc
    36001 ttcatcttct tgtgcagctt gatcaatcgg ctcactggct tcaggtaaga gcgaacgaat
    36061 ttcgttctgt tccagctcaa tggttttgac aattggcgtg gcatcacggt gataaacata
    36121 gggccgccag acagcgacgg ccagagtaag aacggtgagc gaccccaaca taacgcggtg
    36181 tggtcgcggt aaattattaa acgccagggc gacagagcgg gctatctgtt gcacgtaatc
    36241 acttcctcat taatctcctt tcaggcagct cgcatactgg ttggctaatt gattcaggaa
    36301 ttctgaatag cttgttttac ccagtttgat attcgtcccc aggggatcca acgttcccat
    36361 acgaacggat gtccctcgtg cgacgctctc aacgaccgct ggcctgaact gtggctcagc
    36421 aaaaacgcag gttgcttttt gctcaaccaa ctgtgttctt atttcatgta aacgctgcgc
    36481 gccaggttga atctcagggt taacggtaaa atgaccaagc ggtgtcagtc cgaactgttt
    36541 ttcgaagtag ccgtaagcat cgtgaaaaac gaaataacct ttccccttga gcggcgcgag
    36601 ctcgttacca acctgcgttt cggttgaggc taattgtgcc tcaaaatcct tcaggttggc
    36661 gtcaagtttg gctcgacttt gcggcataag ttccactaat tttccatgga ttgcaaccgc
    36721 tgtagcccgc gctatctctg gggaaagcca aagatgcatg ttgaaatcgc cgtgatggtg
    36781 atcttcgtca cttttttccg cgtgatcgtg atcatcatca tcgtcgtgaa tacttttcat
    36841 cagcagcggt ttcacatctt ctagctgcgc aatcgttacc tgtttcgctt ctggtaattt
    36901 acttaccggt ttttgcatga acgcttccat ctccgggcca acccaaacga ctaagtccgc
    36961 gttctgtaag cgttttacat ccgatggacg cagtgaataa tcatgttctg aagcgccgtc
    37021 aggcagtaaa acctgcgttt ctgttacccc atcagcaatg gcagaagcga tgaacccaac
    37081 gggtttaagc gaagcgacaa cggcggcatc tgcggcctgt gttgcaccgc cccagagagc
    37141 ggcggataat gctgcgaaaa gaagcgtttt tttatgtaac ataatgcgac caatcatcgt
    37201 aatgaatatg agaagtgtga tattataaca tttcatgact actgcaagac taaaattaac
    37261 atgacaagtc tggtttccct ggaaaatgtc tcggtttctt ttggccaacg ccgcgtcctc
    37321 tctgatgtgt cgctggaact taaacctgga aaaattttga ctttacttgg gccaaacggc
    37381 gcaggtaagt cgacactggt acgggtagtg ctcggactgg taacacccga tgaaggggtt
    37441 atcaagcgca acggaaaact gcgcatcggc tatgtaccgc agaagctgta tctcgacacc
    37501 acgttgccac tgaccgtaaa ccgtttttta cgcttacgcc ctggcacaca taaagaagat
    37561 attttgcctg cactgaaacg tgtccaggcc gggcatctga ttaacgcacc gatgcaaaag
    37621 ctctcgggtg gcgaaacgca gcgtgtactg ttagcgcgag cattgttaaa tcgaccgcaa
    37681 ttattagtgc tggatgaacc cactcagggc gtggatgtga atggtcaggt ggcgttatat
    37741 gaccttattg accaactgcg tcgtgaactg gattgtggcg ttttaatggt atctcacgat
    37801 ctgcatctgg taatggcaaa aaccgatgaa gtgctttgcc tgaatcacca catttgttgt
    37861 tccggcacac cggaagttgt ttccctgcat ccggagttta tttctatgtt tggtcctcgt
    37921 ggtgctgaac aactgggtat ctatcgccat catcataatc atcgtcacga tttacaggga
    37981 cgaattgttt tgcgtcgggg aaatgatcgc tcatgattga attattattt cccggttggt
    38041 tagccgggat catgctcgcc tgtgccgcgg gtccgctggg ttcgtttgta gtctggcgtc
    38101 gtatgtctta tttcggtgat acgctggctc atgcctcatt acttggcgtc gcgtttggtt
    38161 tgttgctgga cgtgaatcca ttctatgcgg tgattgcagt tacgctgctg ctggcgggcg
    38221 gtctggtatg gctcgagaag cgtccacagc tggcgatcga cacgttatta gggattatgg
    38281 cgcacagtgc cctgtcgctg ggcctggtgg tcgttagtct gatgtctaat attcgtgttg
    38341 atttgatggc ttacctgttc ggtgatttac tggcagtgac gccagaagat ctcatctcta
    38401 ttgcgattgg cgtggtcatc gtggtggcta ttttgttctg gcaatggcgc aatttgctgt
    38461 cgatgacgat tagcccggat ctggcgtttg ttgatggtgt gaaattacag cgcgtgaaat
    38521 tgttgttgat gctggtgacg gcattgacga ttggtgtagc gatgaaattc gtcggcgcgt
    38581 tgattattac ttcactgctg attattcctg ctgctactgc acgtcgcttt gcccgcacgc
    38641 cggaacagat ggctggtgtc gctgttttgg tggggatggt ggcagtgact ggcggtttaa
    38701 ccttttccgc attttacgat acacctgcag gcccgtcggt ggtgctatgc gcggcactgt
    38761 tatttattat cagtatgatg aaaaaacagg ccagctaatc tttcgctgaa catatttgtc
    38821 ggatgcggcg cgagcgcctt atccgacctt gtattatccc tccagtgcag agaaaatcgg
    38881 tcagttttct ctgcctgcag tccgcatgcc ttatccgacc tacggttcgc tatctctggt
    38941 aggcctgata agacgaac
//
LOCUS       DAPOXO010000044        38157 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPOXO010000044 DAPOXO010000000
VERSION     DAPOXO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38157
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.044"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..390)
                     /gene="hns"
                     /locus_tag="ROH59_002641"
     CDS             complement(<1..390)
                     /gene="hns"
                     /locus_tag="ROH59_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HDX4805106.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSL"
     gene            994..1611
                     /gene="tdk"
                     /locus_tag="ROH59_002642"
     CDS             994..1611
                     /gene="tdk"
                     /locus_tag="ROH59_002642"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDX4805107.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEICAEHEQQAIHCVLVDECQFLTRQQAYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYVSVCRKHYKEALEVGSLTAIQERHRHD"
     gene            complement(1897..2944)
                     /locus_tag="ROH59_002643"
                     /pseudo
     CDS             complement(1897..2944)
                     /locus_tag="ROH59_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418698.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(3069..5744)
                     /gene="adhE"
                     /locus_tag="ROH59_002644"
                     /gene_synonym="adhC"
     CDS             complement(3069..5744)
                     /gene="adhE"
                     /locus_tag="ROH59_002644"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDX4805108.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDTTGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
     gene            6221..6868
                     /gene="ychE"
                     /locus_tag="ROH59_002645"
     CDS             6221..6868
                     /gene="ychE"
                     /locus_tag="ROH59_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HDX4805109.1"
                     /translation="MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
     gene            7606..9237
                     /gene="oppA"
                     /locus_tag="ROH59_002646"
     CDS             7606..9237
                     /gene="oppA"
                     /locus_tag="ROH59_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HDX4805110.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRAALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
     gene            9323..10243
                     /gene="oppB"
                     /locus_tag="ROH59_002647"
     CDS             9323..10243
                     /gene="oppB"
                     /locus_tag="ROH59_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HDX4805111.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            10258..11166
                     /gene="oppC"
                     /locus_tag="ROH59_002648"
     CDS             10258..11166
                     /gene="oppC"
                     /locus_tag="ROH59_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HDX4805112.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTPGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            11178..12191
                     /gene="oppD"
                     /locus_tag="ROH59_002649"
     CDS             11178..12191
                     /gene="oppD"
                     /locus_tag="ROH59_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppD"
                     /protein_id="HDX4805113.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPEHELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMDICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            12188..13192
                     /gene="oppF"
                     /locus_tag="ROH59_002650"
     CDS             12188..13192
                     /gene="oppF"
                     /locus_tag="ROH59_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HDX4805114.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(13245..13574)
                     /locus_tag="ROH59_002651"
     CDS             complement(13245..13574)
                     /locus_tag="ROH59_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HDX4805115.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(13609..15069)
                     /gene="cls"
                     /locus_tag="ROH59_002652"
     CDS             complement(13609..15069)
                     /gene="cls"
                     /locus_tag="ROH59_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDX4805116.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            15212..15385
                     /locus_tag="ROH59_002653"
     CDS             15212..15385
                     /locus_tag="ROH59_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HDX4805117.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            complement(15440..16693)
                     /gene="kch"
                     /locus_tag="ROH59_002654"
     CDS             complement(15440..16693)
                     /gene="kch"
                     /locus_tag="ROH59_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HDX4805118.1"
                     /translation="MSHWTTFKQTATKLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILSKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDEQETKADSKESAQK"
     gene            complement(16993..17289)
                     /locus_tag="ROH59_002655"
     CDS             complement(16993..17289)
                     /locus_tag="ROH59_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HDX4805119.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            17513..18229
                     /gene="tonB"
                     /locus_tag="ROH59_002656"
     CDS             17513..18229
                     /gene="tonB"
                     /locus_tag="ROH59_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HDX4805120.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQP
                     ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     VKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQP
                     QYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGK
                     PGSGIVVNILFKINGTTEIQ"
     gene            complement(18269..18667)
                     /gene="yciA"
                     /locus_tag="ROH59_002657"
     CDS             complement(18269..18667)
                     /gene="yciA"
                     /locus_tag="ROH59_002657"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HDX4805121.1"
                     /translation="MSTAHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(18772..19311)
                     /locus_tag="ROH59_002658"
     CDS             complement(18772..19311)
                     /locus_tag="ROH59_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HDX4805122.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQSVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            complement(19341..20084)
                     /locus_tag="ROH59_002659"
     CDS             complement(19341..20084)
                     /locus_tag="ROH59_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HDX4805123.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAVLLIYLFRLYMLIRQ"
     gene            complement(20112..20201)
                     /locus_tag="ROH59_002660"
                     /pseudo
     CDS             complement(20112..20201)
                     /locus_tag="ROH59_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            20440..21078
                     /gene="ompW"
                     /locus_tag="ROH59_002661"
     CDS             20440..21078
                     /gene="ompW"
                     /locus_tag="ROH59_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HDX4805124.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAASPFRHKVGTATTGDIATVHHLPP
                     TLMAQWYFGDSGSKFRPYIGAGINYTTFFNNDFNDTGEGLGLSDLSLKDSWGVAGQVG
                     LDYLINRDWLLNMSVWYMDIDTTAKYKSGVTTVKDSVRLDPWVFMFSAGYRF"
     gene            complement(21124..22254)
                     /locus_tag="ROH59_002662"
     CDS             complement(21124..22254)
                     /locus_tag="ROH59_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HDX4805125.1"
                     /translation="MARPRKYKTNVPGLSPYFDKRNNKVYWRYRHPITGKNHGLGSID
                     QKLAETIAAEANSRLARQQMEQMLSLQEKIISDTGGSSTVTIFLNNYRKIQQERYENG
                     EIKLNTLKQKAAPLRVFDERFGTRPLDAITVKDVVSVLEEYKARGHNRMGQIFRKVLI
                     DVFREAQQTGDVPPGFNPAESAKKPQVRISRQRLTFDEWMMIYNAAEKDGYFLQRGML
                     LALMTGQRLSDICKMQFSDIRDGYLHVEQQKTGTRIAIPLALRCDKLNLTLDDVVSSC
                     RDCVLSPWLLHHHHAKGTAKRGGMVKPATLTVAFKKARDSVDYNWRANGTPPSFHEQR
                     SLSERLFREQGVDTKILLGHSNQKMTDIYNDARGKEWKKLVI"
     gene            complement(22232..22480)
                     /locus_tag="ROH59_002663"
     CDS             complement(22232..22480)
                     /locus_tag="ROH59_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDX4805126.1"
                     /translation="MARLILLTEWAKEEFSEPVPTPSTLSKYAKAGMIFPLPKKVGRR
                     WRVDPQARFVGMVNKPEVIATDHPALKRILEDGAPAKI"
     gene            complement(22545..25016)
                     /locus_tag="ROH59_002664"
     CDS             complement(22545..25016)
                     /locus_tag="ROH59_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HDX4805127.1"
                     /translation="MSKVFICAAIPDEQAIKEEGAVAVATAIEAGDERRARAKFHWQF
                     LEHYPAAQDCAYKFLVCEDKPGIPRPALDSWDAEYMQENRWDEESASFVPVETESDPM
                     NVTFDKLAPEVQNAVMVKFDTCENITVDMVISAQELLQEDMATFDGHIVEALMKMPEV
                     NAMYPELKLHAIGWVKHKCKPGAKWPEIQAEMRIWKKRREGERKETGKYTSVVDLARA
                     RANQQYTENSTGKISPVIAAIHREYKQTWKTLDDELAYALWPGDVDAGNIDGSIHRWA
                     KNEVIDNDREDWKRISASMRKQPDALRYDRQTIFGLVRERPIDIHKDPVALNKYITEY
                     LTTKGVFEDEGRNQSATDTLSSPVPETDAVETAIPDNEKTECKVEVEPSVEREGPFYF
                     LFTDKDGEKYGRANKLSGLDKALAAGATEITKEEYFARKNGTYTGSQQNTDASDTTAQ
                     PDLVKVTADEVNKIMQAASISQPDANKLLAASRGEFVEGISDPNDPKWVKGIETRDSV
                     HQNQSETEQYDQKAEQNSQNALQNEPETKQPEPVVQQEEEKVCTACNQTGGGNCPDCG
                     AVMGDATYQETFNEESQDEAREKDPEEIENAGLPNKECTEGDQHANDNNEIGETANPL
                     IKVNSHRKSTSTSRLWHHLMIDLETMGKNPDAPIISIDAIFFDPQTGDMGPEFSKTID
                     LETAGGVIDRDVIKRWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQVWG
                     NGANFENTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERHNA
                     LDDARYQAKYVSVIWQKLIPNQADF"
     gene            complement(25109..25300)
                     /locus_tag="ROH59_002665"
     CDS             complement(25109..25300)
                     /locus_tag="ROH59_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HDX4805128.1"
                     /translation="MNTAFALVLTVFLVSGEPVDIAVSVHRTMQECVTAATEQKIPGN
                     CYPVDKVIHQDNNEIPAGL"
     gene            complement(25297..25485)
                     /locus_tag="ROH59_002666"
     CDS             complement(25297..25485)
                     /locus_tag="ROH59_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HDX4805129.1"
                     /translation="METLLPNVNTSEGCFEIGVNISNPVFTEDAINKRKHERELLNKI
                     CILSMLARLRPIQKGCWQ"
     gene            complement(26051..26269)
                     /locus_tag="ROH59_002667"
     CDS             complement(26051..26269)
                     /locus_tag="ROH59_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805130.1"
                     /translation="MQKREPVIIAPDYTDDELYEWMRQKINAAQDLKWANEARTKQAE
                     NLSALEQDITRLEKAAALSIARMVTYPR"
     gene            complement(26429..26584)
                     /locus_tag="ROH59_002668"
     CDS             complement(26429..26584)
                     /locus_tag="ROH59_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HDX4805131.1"
                     /translation="MDTIDLGNSESLVCGVFPNQDGTFTAMTYTKSKTFKTENGARRW
                     LERNSGE"
     gene            complement(26857..27573)
                     /locus_tag="ROH59_002669"
     CDS             complement(26857..27573)
                     /locus_tag="ROH59_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000103684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4805132.1"
                     /translation="MSTIATSLGSNIGYMKNTISERIRNRRKDVGLTQQQVAKAIGIS
                     RVSVTKWENGSSKPDGENLYLLSKLLSKSPEWILYGKDGHDKTDDLRLNQYPYISDNI
                     ARLPVLTWEQAGYWDMSCPVTKIPGIKNWVDVMTKTAENSFLLHVEGDAMTNSNGLPT
                     IPDGSTVLITPCSSNIRELVGKIILIQLEGTPNVTLKKVAIDGPNIYLLSLNPLYKPI
                     ELNGGYTIKGKVSQIHQYLD"
     gene            27623..27838
                     /locus_tag="ROH59_002670"
     CDS             27623..27838
                     /locus_tag="ROH59_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX4805133.1"
                     /translation="MFKDDVLRYFKKKRLVAEALGISHVAVVRWKAVIPKLRAMELDE
                     ITNGELKYNPELYKKQDSTSNEGKNDS"
     gene            27835..28260
                     /locus_tag="ROH59_002671"
     CDS             27835..28260
                     /locus_tag="ROH59_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDX4805134.1"
                     /translation="MKIKHEHIRMAMNAWAHPDGEKVPAAKITKAYFELGMTFPELYD
                     DSHPEALARNTQKIFRWLDKDTPDAVEKMQALLPAIEKAMPPLLVARMRSHSSEYYRE
                     IVERRDRLVKDVDDFVASAVVLYDQMNRGGPAGNAVVMH"
     gene            28283..29245
                     /locus_tag="ROH59_002672"
     CDS             28283..29245
                     /locus_tag="ROH59_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4805135.1"
                     /translation="MSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAIE
                     TIRRQIGARSESTVKSAIAELAKEGWLTKEERKVGGRNVSNIYRLNVEKLEAAAAAAR
                     ESYKPKRKISPAKNDPLTVDPSNIDPSTVDPSNFDGSTVDKKLPIRGPMIDPDPSVLK
                     PDPSDKRSSCPDASQPDPQTAEQDFLTRHPDAVVFSAKKRQWGSQEDLVCAQWIWGRI
                     VSLYEQAASYDGEITRPKEPNWTAWANDVRTMRMLDGRTHRQICEMFGRLQRDSFWVK
                     NIMSPAKLREKWDELVIRLGRSPAQRCVNHISEPDTEIPPGFRG"
     gene            29252..29998
                     /locus_tag="ROH59_002673"
     CDS             29252..29998
                     /locus_tag="ROH59_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDX4805136.1"
                     /translation="MKNIAAVGVLERIRRLAPQGSVPPYRTVEEWREWQLAEGRKRSE
                     EINRQNRQLRVEKILNRSGIQPLHSKCSFANYQVQNDGQKYALSQAKSIADELMTGCT
                     NFVFSGKTGTGKNHLAAAMGNRLMVKGRSVIIVTVSDVMSVLHDSYDNGKSGEKFLQE
                     LCGVDLLVLDEIGVQRETKNEQVVLHQIIDRRTASLCSVGMLTNLNHAAMSTLLGERI
                     MDRMTMNGGRWVTFNWDSWRPNVSNMRVVK"
     gene            30020..30790
                     /locus_tag="ROH59_002674"
     CDS             30020..30790
                     /locus_tag="ROH59_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HDX4805137.1"
                     /translation="METVSDALKALKKASSHVVAARLGISREEAVNELWELKRKGVVD
                     KTGHTWFLAGEGESRVTEERPVKSEAQDMLTGEVEQKVTADMMIEFIGQDGAKTCEEL
                     AGKFGVSTRKVASTLAVVTATGRLARVNQNGKFRYCMPGDNLPAEPKAALVTESDGKA
                     FPQPAGAALPVREAATQEEIKTETVADIVQPLPSFTETQADELIFPSLRRANLALRRA
                     KSDVQKWERVCAALRELNKHRDIVRQITDSSRRVVSEK"
     gene            30806..31231
                     /locus_tag="ROH59_002675"
     CDS             30806..31231
                     /locus_tag="ROH59_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HDX4805138.1"
                     /translation="MAKVFTQEEREKIKGQVVELVRLSGRETLRQLEAKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKVKKPAVVDPDLIWSLPDG
                     EIRRYDRRLNIICRECRKSEAMQRVLAFYQGNVRYFRRY"
     gene            31406..32071
                     /locus_tag="ROH59_002676"
     CDS             31406..32071
                     /locus_tag="ROH59_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDX4805139.1"
                     /translation="MTIADFKRPKLELPNGANKLLLHSCCAPCSGEVMEALQASGIDY
                     TIFFYNPNIHPQKEYLIRKDENIRFAEQHGVPFIDADYDTDNWFERAKGMEWEPERGI
                     RCTMCFDMRFERTALYAAENGFSVISSSLGISRWKNMQQVNECGRRAVAHYPGMVYWD
                     YNWRKQGGSSRMIEISKREKFYQQEYCGCVYSLRDTNLHRKSQGRPLIKIGQLHYGKE
                     EKE"
     gene            32309..32464
                     /gene="hokD"
                     /locus_tag="ROH59_002677"
     CDS             32309..32464
                     /gene="hokD"
                     /locus_tag="ROH59_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HDX4805140.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRLRTGQTEVAVF
                     TAYEPEE"
     gene            32632..32904
                     /locus_tag="ROH59_002678"
     CDS             32632..32904
                     /locus_tag="ROH59_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805141.1"
                     /translation="MAHKTKFHNSDTDLAIRHGRRSHAFKTDWYQHPPCTEEQAEWLI
                     HNYRRRGYEIKKALSLDYRHWIISVRLPYSERPPRPSRTFQQRIWR"
     gene            32906..33961
                     /locus_tag="ROH59_002679"
     CDS             32906..33961
                     /locus_tag="ROH59_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HDX4805142.1"
                     /translation="MRVLLRPVLVPELGLVIVKPGRESMPVFHNTRVLVEPEPKSMRN
                     LPSGVVPAVRQPLAEDKSLLPFFSDERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SETVIHRYGTGAMVLCWHCDNQLRDQTSESLGQLAHQNLFAWMIDVIRHAMNGSQERE
                     LSLAELSWWAVRNQVADALPEAVLRRSLGLRAEKIRSMYRESDIVPGEQTATSILKQR
                     TKNLAPLPHAHQQNPPQEKTVVSIAVDPESPAQYLQRQKSQREEMPVYTRWVKTQKCM
                     TCGNQADDPHHIIGHGLGGMGTKADDLFVIPLCRKCHSELHAGVKDFEEKHGSQLLLL
                     IRFLMHARNSGVLKWKA"
     gene            33962..34342
                     /locus_tag="ROH59_002680"
     CDS             33962..34342
                     /locus_tag="ROH59_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDX4805143.1"
                     /translation="MTERIEFVLPYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVR
                     QQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDALTHAGLLMDDEQFDEINIVR
                     GQPVSGGRLGVKIYPIMHEEQVKK"
     gene            34339..35160
                     /locus_tag="ROH59_002681"
     CDS             34339..35160
                     /locus_tag="ROH59_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDX4805144.1"
                     /translation="MKLEDLPKYYSPKSPGLTDASASTSKDALSITDVMAAQGMTQNR
                     AEMGFSAFLGKMGISMNDRARATELLADYALSRCDRVAALRKLPAEIKPVVMRIMASY
                     AFEDYARSAASKKQCPCCRGEKFIEGEVFTNKVQYPDGKPPVWAKCTKGVYPSYWEEW
                     KKIREVVKVSCPECKGKGEISTACKDCRGRGVAIHREESVKRGMPVIRDCQRCGGRGC
                     ERLPSTEAFNAICKVTSAITLDTWKKSVKRFYDTLVVRFDIEEAWAERQLKRVTR"
     gene            35387..35584
                     /locus_tag="ROH59_002682"
     CDS             35387..35584
                     /locus_tag="ROH59_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDX4805145.1"
                     /translation="MLKQQDMTETARVVFNELSVTEPATAGEIAQNTYLSRERCQLIL
                     TQLVMAGLADYQFGCYRRLPQ"
     gene            35736..36785
                     /locus_tag="ROH59_002683"
     CDS             35736..36785
                     /locus_tag="ROH59_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HDX4805146.1"
                     /translation="MANTVKISSCELINADCLEFIRSLPENSVDLIVTDPPYFKVKPE
                     GWDNQWKGDDDYLKWLDQCLAQFWRVLKPAGSLYLFCGHRLASDIEIMMRERFSVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERILFAEHYQGPYRPKDAGYAAKGSALKQHVMA
                     PLISYFRDARAALGITAKQIADATGKKNMVSHWFSASQWQLPNESDYLKLQSLFARVA
                     EEKHQRGELEKPHHQLVDTYTSLNRQYVELQSEYKHLRRYFGVTAQVPYTDVWTHKPV
                     QFYPGKHPCEKPAEMLQQIISASSRPGDLVADFFMGSGSTVKAALALGRRAIGVELET
                     GRFEQTVREVQGLIV"
     gene            36835..36910
                     /locus_tag="ROH59_002684"
     tRNA            36835..36910
                     /locus_tag="ROH59_002684"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36868..36870,aa:Ile,seq:cat)
     gene            37011..37087
                     /locus_tag="ROH59_002685"
     tRNA            37011..37087
                     /locus_tag="ROH59_002685"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37045..37047,aa:Arg,seq:tct)
     gene            37587..37718
                     /locus_tag="ROH59_002686"
     CDS             37587..37718
                     /locus_tag="ROH59_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HDX4805147.1"
                     /translation="MIAYCFCEWHCCSRIMSVLADGVLVAGVVVVAFPLLKKKTPDC"
     gene            complement(37999..>38157)
                     /locus_tag="ROH59_002687"
     CDS             complement(37999..>38157)
                     /locus_tag="ROH59_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707425.1"
                     /note="interacts RssB preventing the degradation of the
                     stress sigma factor RpoS; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HDX4805148.1"
                     /translation="TIYNVVPFNKTFWNLIKNSQECPTNTDNVLNECFNNRCTLQICP
                     YGLKQQSP"
BASE COUNT         9703 a         8830 c         9644 g         9980 t
ORIGIN      
        1 gagggattta ccttgctcat ccattgcttt tttgattaca gctggagtac ggccctggcc
       61 agtccaggtt ttagtttcgc cgttttcgtc aacgtagcta tattttgccg gacgctgagc
      121 acgcttagct ttggtgccag atttaacggc agcaaggcta ttcagcagtt cgttcgggtc
      181 aataccgtca gcgatcagca tttcgcgata ttgctgcagt ttacgagtgc gctcttcaac
      241 ttcagcagca gccgcgcttt cttcttcgcg acgttcgtta acaacaactt ctaatttttc
      301 cagcatttct tccagcgttt caagtgtaca ttctcttgcc tgcgcacgaa gagtacggat
      361 gttgttcaga attttaagtg cttcgctcat tgtagtaatc tcaaacttat attggggtgg
      421 tttgttgagg taataataga gccttaaatt cagttgtgca atagccagga atgtaaggaa
      481 ttcaaaattg ttctttattt tgtgccgcca ataaatatct tttcataaaa ttagccagaa
      541 aagacgcggc atatagccct atttgcaccg atgatttcgc agcacgtgag gttaaaactt
      601 cctgattcat gtcacatttt atggggagat aatcgtaggc tgacgacctt tcagtcttct
      661 gtattagtcg tgtttacgag aattccctat taagcgaatg atgaaaagta gaacagtcgc
      721 aataagagca gggacttagt attgcactat ctcctggagg tcaacagagg gctattacat
      781 gcgcaacagg ttaaagattg tgaatagtta ccggcagtca tttacccgct tataacaagc
      841 gaggcagttg taatgatagc tcagaaggat tatgcaaggc ttcgtaaggg agaacgcata
      901 taccacttct gtgcatactg ttgagctgaa aaactgacga attatgataa actccagcca
      961 actttatttc atatcattga gggcctgtgg ctgatggcac agctatattt ctactattcc
     1021 gcaatgaatg cgggtaagtc tacagcattg ttgcaatctt catacaatta ccaggaacgc
     1081 ggcatgcgca ctgtcgtata tacggcagaa attgatgatc gctttggtgc cgggaaagtc
     1141 agttcgcgta taggtttgtc atcacctgca aaattattta accaaaattc atcattattt
     1201 gatgagattt gtgcggaaca tgaacagcag gcaattcatt gcgtactggt tgatgaatgc
     1261 cagtttttaa ccagacaaca agcatatgaa ttatcggagg ttgtcgatca actcgatata
     1321 cccgtacttt gttatggtct acgtaccgat tttcgaggtg aattatttat tggcagtcaa
     1381 tacttactgg catggtccga caaactggtt gaattaaaaa ccatctgttt ttgtggccgt
     1441 aaagcaagca tggtgctgcg tcttgatcaa gcaggcagac cttataacga aggtgagcag
     1501 gtggttattg gtggtaatga acgctacgtt tctgtatgcc gtaaacacta taaagaggcg
     1561 ttagaagtcg gctcattaac ggctattcag gaaaggcatc gccacgatta ataagaattt
     1621 ctttactgac agggtgagca gggcgctttt atccctgtca gttcgtttta cgcacttctt
     1681 ccgggctata cacccttctc ggcagttttt taacgccgtt atacgcctca cagagcgctt
     1741 atacaccgac attgacttgt aacctgtaaa gtacaatatc gctgtgtgta ggcgttatac
     1801 atcgtcgcaa atatgatgaa ggacaatgct gccggtttat ggaaaagttg ctttgggaaa
     1861 ataaaaaacg gccccagaag gggtaatgcc agtcagttaa gcaactgact ggctcttttt
     1921 cggggctgtg gagtatttcc agggcctctc ctttatcact ctcgggaagg ccctttctct
     1981 tcttgtcggt aatttcacta gttgtcccat acttgcaaga tcgcgcatca gctccggtat
     2041 acgtcccggg gaagcgcatg gcgtccgtca tcgacgtcag cagatggcag acttttcctt
     2101 tgcgcgtcac ggtcagcagg cggactgtca cctcatttcc cagtcccggc cacttttttc
     2161 gtgcctgcgg gctggtgttc agcttcacca gatgatcgcc tttacccagt tttctgatct
     2221 cttcatattg cgctcccttt ctgagaggga tcatccagtg gcggtgttct cccgccaggc
     2281 tccaggtatt taacagtccc agtgagtaat aacctttatc cattaacgtc agggtgttat
     2341 cgccggtttg ttctataagt tgctcagcaa gctcattttc gctgttcttc atcgtgccga
     2401 aggctgcagc cgtcagcaga tggctggtca gttccatctg gcagaccatt ttgacctgca
     2461 ggtagagcgc cgggttcccg gcatgtgtct ggcgggggaa ggctgcatcg ttctctggtg
     2521 tatccggtgt gcgccagaac acaccatcga tggccagcag ggtcaggccg caccagtgcg
     2581 gatgcggcgt ggtgttatgc cagagctgcg ctgttttcgt gaacacgcgg cggacagcct
     2641 caattcccag acgctggcgg gtctgaataa cggcactggg ggcaacgaag gggcgattgc
     2701 ccggcagcat gatatccagg cgattcacaa tctggtgaag aggttcttta cgctcaagcg
     2761 ccatgccaac aatacaccag accatcattt cgaggggaag acggcgcttg cgtagcgtta
     2821 cagtacctga ttcggcaagg caacgagaga tgagttcggg gtcgaggtaa tcccccagag
     2881 aagtcagtgg gttacgcaga gaatcgtaac gggataccaa atcaagggcc tgtccaatga
     2941 gcataaaaaa atccggaaac gagtgagcgt ttccggattc ttacacagcc actggatcgg
     3001 tcaactgatc cttaactgac tggcattacc ccagaagggg ccgttatgtt gccagacagc
     3061 gctactgatt aagcggattt tttcgctttt ttctcagctt tagccggagc ggcttctttc
     3121 ttcgctgcag tttcgccttc tacataatca cgaccgtagt aagtatccag cagaatctgt
     3181 ttcagctcgg agatcagcgg gtaacgcggg ttagcgccgg tgcactggtc atcgaatgca
     3241 tcttcagaca gtttatccac gttcgccagg aagtctgctt cctgaacgcc agcttcacgg
     3301 atagatttcg gaatacccag ttcagctttc agtgtttcca gccatgccag cagtttctcg
     3361 atcttagcag cagtacggtc gcccggtgcg ctcagaccca ggtggtcagc aatttcagca
     3421 taacgacggc gagcctgcgg acggtcatac tggctgaatg cagtctgctt ggtcgggttg
     3481 tcattcgcgt tgtagcgaat aacgttacaa atcagcaggg cgtttgccag accgtgcgga
     3541 atatggaact gggaacccag tttgtgcgcc attgagtgac atacacccag gaaggcgttc
     3601 gcaaacgcga tacccgcgat agtcgctgca ctgtgaacac gttcacgcgc taccggattt
     3661 ttagaccctt cgtggtagga cgctggcaga tattctttca gtagtttcag tgcctgcaga
     3721 gcctgaccat cagagaactc agatgccagt acagaaacat aagcttccat ggcgtgagtt
     3781 actgcgtcca gaccaccgaa agcacacagg gacttcggca tgtccataac aaggttggcg
     3841 tcgacaatcg ccatatccgg ggtcagtgca tagtctgcca gcggatattt ctgaccagta
     3901 gtgtcgtcag ttacaaccgc aaacggagtg acttcagaac ctgtaccaga agtggtggtg
     3961 acagcgatca ttttcgcttt cacacccatt ttcgggaact tgtagatacg tttacggata
     4021 tccataaagc gcagcgccag ttcttcgaag tgagtttccg gatgttcgta cataacccac
     4081 atgatcttcg cagcgtccat cggggaacca ccacccagcg cgataatcac gtctggtttg
     4141 aaggagtttg ccagttctgc acctttacga acgatgctca gggtcgggtc agcttctact
     4201 tcgaagaaga cttcagtttc aacgcctgct gctttcaata cggaagtgat ctgatcagca
     4261 tagccattgt tgaacaggaa gcggtcagtc acgatgagcg cacgtttgtg gccatcagta
     4321 atcacttcat ccagcgcgat tggcagggag ccacggcgga agtagataga tttcggaagt
     4381 ttgtgccaca acatgttttc agctcgctta gcaacggttt tcttgttgat caggtgtttc
     4441 ggaccaacgt tttcagagat ggagttacca ccccaggaac cacaacccag agtcagggaa
     4501 ggtgcgagtt tgaagttata caggtcaccg ataccaccct gagaagccgg ggtgttaatc
     4561 aggatacgag ccgttttcat tttctgaccg aagtaagaaa cgcgagccgg ttggttatcc
     4621 tggtcagtgt acaggcaaga ggtatgaccg ataccgccca tagcaaccag tttttctgct
     4681 ttttctaccg cgtcttcgaa atccttagca cggtacattg ccaaagtcgg ggacagtttt
     4741 tcatgtgcga acggttcgct ttcatcaaca acggttactt caccgatcag aatcttggtg
     4801 ttttctggta cagagaagcc tgccagttca gcaattttat aggctggctg accaacgata
     4861 gccgcgttca gcgcaccgtt tttcaggata acgtcctgaa cagctttcag ctctttaccc
     4921 tgcaacagat agccaccgtg ggttgcgaaa cgttcacgta ctgcgtcata aacagagtca
     4981 acaacaacaa cagactgttc agaagcacag attacgccgt tgtcgaaggt tttggacatc
     5041 agtacagatg caactgcacg tttgatatca gcagtttcat cgataacaac tggagtgttg
     5101 cccgcgccta cgccgatagc tggtttaccg gagctgtatg cggctttaac catgcccgga
     5161 ccaccagtcg cgaggatcag gttgatgtct gggtggtgca tcagtgcgtt agacagctca
     5221 acagaaggtt gatcgatcca gccgatcaga tctttcggag caccggcagc gatagcagcc
     5281 tgcagaacga tatcagccgc tttgttggtt gcatcttttg cacgcgggtg cggggagaag
     5341 ataatggcgt tacgggtctt caggctgatc agtgatttga agatagcagt tgaagtcggg
     5401 ttagtggtcg gaacgatgcc gcaaataata ccgatgggtt cagcgatagt aatggtacca
     5461 aaagtgtcgt cttcagacag aacaccacag gttttttcat ctttataggc gttgtagata
     5521 tattcagaag caaagtggtt tttgatcact ttatcttcga cgatacccat gccggattcg
     5581 gcaacggcca ttttcgcgag tgggattcga gcatctgcag cagccagagc ggcggcgcgg
     5641 aagattttgt ctacttgctc ttgagtgaaa ctggcatatt cacgctgggc tttttttaca
     5701 cgctctacga gtgcgttaag ttcagcgaca ttagtaacag ccataatgct ctcctgataa
     5761 tgttaaactt ttttagtaaa tcatctgctc gaatacgaga gtatagtcag tgcggtgatg
     5821 atttgcttaa ccgatggaaa tcaaaagctt actcgcgctc acactcactg tgatttacta
     5881 aaagagttta aacattagag ttattatctc taatgcgtca cttccaggtg gcgtaagcaa
     5941 gattactcac ttctgggtac tgattacgtg atcaagatca aatttttgca aagctgacac
     6001 ctttcagcat ggcttttcgc cattatagct aacagttaac aaattgtagt atgatttgtt
     6061 ggctacatta gcatgttttg cacaactaga taacaataac gaatgatagc aattttaagt
     6121 agttaggagg tgaaaaatgc tgtcaaaagg cgtattgtca gcgcgtcttt tcaaccttat
     6181 ttatggctaa cattatccgg cttttgcttc ggagctaacc gtgattcaga ccttttttga
     6241 ttttcccgtt tacttcaaat ttttcatcgg gttatttgcg ctggtcaacc cggtagggat
     6301 tattcccgtc tttatcagca tgaccagtta tcagacagcg gcagcgcgaa acaaaactaa
     6361 ccttacagcc aacctgtctg tggccattat cttgtggatc tcgctttttc tcggcgacac
     6421 gattctacaa ctttttggta tatcaattga ttcattccgt atcgccggtg gcatcctggt
     6481 ggtgacaata gcgatgtcga tgatcagcgg caagcttggt gaggataaac agaacaagca
     6541 agaaaaatca gaaaccgcgg tgcgtgaaag cattggtgtg gtgccattgg cgttgccgtt
     6601 gatggcgggg ccaggggcga tcagttctac catcgtctgg ggtacgcgtt atcacagcat
     6661 tagctatctg tttggtttct ttgtggctat tgcattgttc gctttatgtt gctggggatt
     6721 gtttcgcatg gcaccgtggc tggtacgagt tttacgccag accggcatca acgtgattac
     6781 gcgtattatg gggctattgc tgatggcgtt ggggattgaa tttatcgtta ctggtattaa
     6841 ggggattttc cccggcctgc ttaattaatt cctttcaaat gaaacggagc tgccatgctc
     6901 cgtttacttc gtcattattt ttactttgtt cctgcgcagt tatcaaaagc aaaaggaata
     6961 ggtaaaaata ttcttctcaa attacagtta gttataagga tttccttaac tgcttctcct
     7021 caccatcatg ttattttcgc cacatcataa tcctgggctt gctgaagaat aattgaaatg
     7081 atattagtaa ttccactgcc tttggtagag gaaagtgcta aataataatc aattgttaaa
     7141 ttattgtgca tttcactact ggaactgtaa tcagaaaaga gagacatgct taactaacct
     7201 ctatttgatt gaattgaaag atgtttgtta aggcatggat gcaagctata gattctggta
     7261 cggtcaataa aagagaattg cttaacaatt ttgcaaaatg tattggcgag taagaaccgc
     7321 atttggtact ttccgggcaa ccgccaggcg attctttatt ggtaatgaga ataattaaca
     7381 attaaagacc gtcgcgaaag aataatgtgt ctcgacaggg gagacacagt acgaatcgac
     7441 ataaggtgat cgtctgaatc accagaataa ataaagtcgg tgatagtaat acgtaacgat
     7501 aaagtaacct gacagcagaa agtctccgag cctgtgcagg gtcccaatcc gggattacac
     7561 atgctggtta ataccagtaa ttataatgag ggagtccaaa aaacaatgac caacatcacc
     7621 aagagaagtt tagtagcagc tggcgttttg gctgcgctta tggcagggaa tgtcgcgctg
     7681 gcagctgatg tacccgcagg tgtcacactg gcggaaaaac aaacgctggt acgtaacaat
     7741 ggttcagaag ttcagtcatt agatccgcac aaaattgaag gtgttccgga gtctaatatc
     7801 agccgagacc tgtttgaagg cttactggtt agcgatcttg acggccatcc ggcacctggc
     7861 gtcgctgaat cctgggataa taaagacgcg aaagtctgga ccttccattt gcgtaaagat
     7921 gcgaaatggt ctgatggcac gccagtcaca gcacaagact ttgtgtatag ctggcaacgt
     7981 tctgttgatc caaacactgc ttctccgtat gccagttatc tgcaatatgg gcatatcgcc
     8041 ggtattgatg aaattcttga agggaaaaaa ccgattaccg atctcggcgt gaaagctatt
     8101 gatgaccaca cattagaagt caccttaagt gaacctgttc cgtacttcta taaattactt
     8161 gttcatccat caacttcacc ggtgccaaaa gccgctatcg agaaattcgg cgaaaaatgg
     8221 acccagcctg gtaatatcgt caccaacggt gcctatacct taaaagattg ggtcgtaaac
     8281 gaacgaatcg ttcttgaacg cagcccgacc tactggaaca acgcgaaaac cgttattaac
     8341 caggtaacct atttgcctat tgcttctgaa gttaccgatg tcaaccgcta ccgtagtggt
     8401 gaaatcgaca tgacttataa caacatgccg atcgaattgt tccagaagct gaaaaaagag
     8461 atcccggacg aagttcacgt tgatccatac ctgtgcactt actattacga aattaacaac
     8521 cagaaaccgc catttaatga cgtgcgtgtg cgtaccgcac tgaaattggg tatggaccgc
     8581 gatatcattg ttaataaagt gaaagcgcag ggcgacatgc ccgcctatgg ttacactcca
     8641 ccgtatactg atggcgcaaa attgactcag ccggaatggt ttggctggag ccaggaaaaa
     8701 cgtaacgaag aagcgaaaaa actgctggct gaagcgggtt ataccgcaga caaaccgttg
     8761 accatcaacc tgttgtataa cacctccgat ctgcataaaa agctggcgat tgctgcctct
     8821 tcattgtgga agaaaaacat tggtgtaaac gtcaaactgg ttaaccagga gtggaaaacg
     8881 ttcctcgaca cccgtcacca gggcactttt gatgtggccc gtgcaggctg gtgtgcagac
     8941 tacaacgaac caacttcctt cctgaacacc atgctgtcga acagctcaat gaataccgcg
     9001 cattataaga gcccggcctt tgacagcatt atggcggaaa cgctgaaagt gactgacgag
     9061 gcgcagcgtg cagctctgta cactaaagca gaacaacagc tggataagga ttcggccatt
     9121 gttcctgttt attactacgt gaatgcgcgt ttggtgaaac cgtgggttgg tggctatacc
     9181 ggcaaagatc cgctggataa tacctacacc cggaatatgt acattgtgaa gcactaatgg
     9241 caatacgtgg ggcaggagtg tcctgctcca cggtgtctga tttttatcgc attacagaag
     9301 gcacaggcca gaaggtaggg caatgttaaa atttattcta cgtcgctgtc tggaagcgat
     9361 tccgacgcta tttattctta ttactatttc gttctttatg atgcgcctcg cgccgggcag
     9421 tccttttacc ggcgaacgta ctttaccacc ggaagtgatg gccaatatcg aagcgaaata
     9481 tcatcttaat gatccgatca tgacacagta tttcagctac ctgaaacaac tggcgcatgg
     9541 cgatttcggt ccatcgttta aatataaaga ttattcggtc aatgacctgg ttgcatccag
     9601 ttttcccgtt tctgccaaac tgggagctgc agcatttttt cttgcggtaa tactgggtgt
     9661 tagtgctggc gttattgccg cattaaagca aaacaccaaa tgggactata ccgtgatggg
     9721 gctggcaatg accggggttg ttatccccag ttttgtggtt gcgccattat tagtcatgat
     9781 atttgcgatc attttgcatt ggctgccggg cggtggctgg aatggtggag cgcttaaatt
     9841 catgatattg ccaatggtgg cgttatcact cgcctatatc gccagtattg cgcgtattac
     9901 ccgtggctct atgattgagg ttttacactc caactttatt cgtactgccc gggcgaaagg
     9961 gttacctatg cggcggatca ttttacgcca cgcattaaaa cctgctctgt tacccgtgct
    10021 ctcctatatg gggcccgcat ttgtcggcat tattaccggt tcgatggtca tcgaaaccat
    10081 ttatggttta ccggggattg ggcaattgtt cgttaatggc gcattgaacc gtgactattc
    10141 cttagtgtta agtctgacca ttctggttgg cgcgttaacc attttgttta atgccattgt
    10201 cgatgtgcta tatgcggtta tcgacccgaa aatccgttac tgatactgga gctcgcgatg
    10261 atgttaagta agaaaaacag cgagacgctg gaaaatttca gtgaaaagct ggaggtcgaa
    10321 gggcgcagct tgtggcagga cgcacgtcga cgttttatgc ataaccgtgc ggcggttgcc
    10381 agtctgatag tgctggtgct gatcgcgtta tttgtaatcc tggcaccgat gctttcgcag
    10441 tttgcctatg acgatactga ctgggcgatg atgtccagcg ccccggatat ggagtccggt
    10501 cactactttg gtactgactc atccggtcgc gacctgcttg tgcgcgttgc gattggcggg
    10561 cgtatctcac tcatggtcgg tgttgctgcg gcactggtgg cagtggtcgt ggggacactt
    10621 tatggttcgc tttccggtta tctgggcggt aaagtggatt cggtaatgat gcgtctgctg
    10681 gaaatcctca actccttccc attcatgttc ttcgtcattt tgctggtgac ctttttcggt
    10741 caaaacatcc tgctgatttt cgtggcgatt ggcatggttt cctggctgga tatggctcgt
    10801 attgtgcgtg ggcaaaccct gagtctgaag cgcaaagagt ttattgaggc ggcacaagtt
    10861 ggcggtgtat cgacgccggg cattgttatt cgccacattg tgccgaacgt actcggtgtg
    10921 gtggtggtct atgcgtcgct tctggtgccc agcatgatcc tctttgaatc tttccttagc
    10981 ttcctgggat taggtacaca agagccgtta agcagctggg gtgcattgct gagtgatggc
    11041 gcgaactcga tggaagtctc tccatggtta ctgttgttcc cagcgggatt cctcgtggta
    11101 acgctgtttt gtttcaactt tatcggcgat ggcttgcgtg atgccctcga cccgaaagat
    11161 cgttaaggag tgcagccatg agcgtaattg aaactgcaac tgtgccgctc gcacaacaac
    11221 aggctgacgc actgctgaac gtgaaagatt tgcgtgtcac ctttagtacc ccggatggcg
    11281 acgtcacggc ggtcaatgat ttgaattttt cgctacgtgc cggagaaacg ctgggcatcg
    11341 taggtgagtc tggttcgggc aaatcgcaaa ccgcattcgc gttgatgggc ctgttagctg
    11401 ccaacggacg tattggcgga tcggcaacct tcaatgggcg tgaaatcctc aatttgccag
    11461 agcatgaact caataaactg cgagctgaac aaatctcaat gatttttcag gacccaatga
    11521 cttcgttgaa tccctatatg cgcgtcggtg agcagttgat ggaagtgctg atgctgcata
    11581 agaacatgag caaagctgag gcgtttgaag aatcggtgcg gatgctcgat gcggtaaaaa
    11641 tgccggaagc gcgtaaacgc atgaaaatgt acccgcacga attttctggc ggcatgcgtc
    11701 agcgagtcat gattgcgatg gcattgctat gtcgacctaa gctgctgatt gcggatgaac
    11761 ccactactgc gctggacgtc accgtacagg cgcagatcat gacgctattg aatgaactga
    11821 agcgggaatt taataccgcc atcattatga ttacccacga tcttggcgtg gtggcgggga
    11881 tctgcgacaa agtgctggta atgtacgccg ggcgcacgat ggaatatggc aacgcgcgcg
    11941 atgtctttta tcaacccgta catccttatt ctatcggttt gctcaacgcg gtgccgcgtc
    12001 tcgatgcgga aggtgaaaca atgttgacta ttccgggtaa tccgccaaac ctgctgcgat
    12061 taccgaaagg ttgcccgttc cagccacgtt gtccgcatgc gatggatatt tgtagtagcg
    12121 caccgccgct ggaagagttt acgcctggcc gtctgcgtgc ttgctttaaa ccggtggagg
    12181 aactgttatg aatgctgtaa ccgaaggaag aaaagtcctc ctcgaaatcg ccgatctgaa
    12241 agtgcacttt gaaatcaaag atggcaaaca gtggttctgg caaccgccga aaacgctcaa
    12301 agccgtcgat ggtgtaactc ttcgcctgta tgaaggggaa acattaggtg tggtagggga
    12361 atcgggatgc ggtaagtcca cctttgctcg cgccatcatt ggcctggtta aagcgaccga
    12421 cggtcatgtt gcctggttag gtaaagagtt gctgggcatg aagcccgatg aatggcgtgc
    12481 cgtacgcagt gatattcaga tgattttcca ggatccgttg gcatcgctga acccgcgtat
    12541 gaccatcggc gagatcatcg ctgaaccact gcgtacttat catccgaaaa tgtcacgcca
    12601 ggaagttcgc gagcgcgtga aggcgatgat gctgaaagtc ggtttgttgc ctaacctgat
    12661 taaccgctat ccgcatgagt tctccggtgg gcagtgccag cgtatcggga ttgctcgcgc
    12721 tcttattctt gaaccgaagc tgattatctg tgatgagccg gtgtcggcgc tggacgtgtc
    12781 aattcaggcg caggtggtca acctgctcca gcagttgcaa cgtgagatgg gattgtcatt
    12841 aatttttatc gctcacgacc tggccgtggt aaaacacatt tccgatcgtg tgctggtgat
    12901 gtatctcggc catgcggtag aactggggac ctatgatgag gtctaccaca atccgctaca
    12961 tccttacacc agggcattga tgtcggcagt ccccatacct gatccggatc tggagaagaa
    13021 caaaaccatc cagttactgg aaggggaatt accgtcgccg atcaacccgc cttccggttg
    13081 tgttttccgt acccgttgtc cgattgcagg tccggagtgc gccaaaacac gtcctgtgct
    13141 ggaagggagt ttcagacacg ccgtttcttg cctgaaagtc gatccgcttt aaaagcaata
    13201 agggctgaca gttgtcagcc cttattcacg ccaaaagcga ttatttattc ccgccagatg
    13261 atatggcaaa gtttgtgatc tttttcgcgg cataacagaa tgcgcgcgaa aacatcgttg
    13321 atttcaccat cttcactgtc cgccagacca atcaccactt cggcaaaaaa gtccgggttc
    13381 aaatcgaaat caacatgttc ctgccagtct tccgccggat cgaataactc cgcgccgccg
    13441 cgctcttcaa actgaagatt gaacagcaga acatcagctg gatcgagatt gtcggcagcc
    13501 agttcgagaa aaatatcgta ggcctgctca agcgtttcat cttcagtcag gcgattgttt
    13561 agatccatat ccatagtcac tacctgttta acctctgttg gcgacgtttt acagcaacgg
    13621 gctgaagaag taaaacagtc gctcggcgac acgttgccat aatggacgtt ttagccataa
    13681 acgggcatcg agcagacgag aacgcgaaat ataatcgtcc tgaacggcgg cgaggtctgc
    13741 accaaaacct ttatcgtcga ttgccagggt aatctcgaaa tttagccaca gactacgcat
    13801 atcaaggtta acggtgccaa ccagacttag ttctccatcg accagcacgc tcttggtatg
    13861 cagtaacccg ccttcaaact gataaatttt aaccccagca gccagcagtt ctgtaaagaa
    13921 tgcgcgactg gcccagccga ccagcatcga gtcatttttt cgcggaagga taatactgac
    13981 atccaccccg cgctgcgccg ccgtgcaaat cgcatgaagt aaatcatcgc ttggcacaaa
    14041 atagggcgtt gtcatgatca aatattcacg agccgaataa gcagcagtca ataatgcctg
    14101 gtgaatgaga tcttccggaa agccggggcc agaagcaatt gtgtgaatgg tgtgaccact
    14161 ggcctgctca aacggcataa tattgacatc tggtggcggc ggcagaatac gtttcccggt
    14221 ttcaatctcc cagtcgcagg aataaataat ccccatcgcg gtggcgatgg ggccttccat
    14281 acgcgccatc agatcaatcc attgccctac acccgcatct tgtttgaagt agcgagggtc
    14341 gaccatattc atgctgccgg tgtacgcgat gtaattatcg atcatgatca tcttgcgatg
    14401 ttggcgcagg tccatacggc gtaaaaacac acgcatcaga ttgaccttta aggcttcgac
    14461 aacttcaata ccggcattac gcattagctc gggccacggg ctgcggaaaa aagccacact
    14521 cccggcggag tcgagcatca atcggcaatg aataccgcgc cgtgcagcgg ccattaatga
    14581 ttcagccacc tggtccgcca tgccgccggg ctgccagata taaaacacca tctcaatatt
    14641 atggcgcgcg agctggatgt cgcggattaa cgcctgcatc acatcatctg actcggtcat
    14701 cagttgtagc tgattccctt tgaccccagc gatcccctga cgacgctcgc aaagcttgaa
    14761 taatggcgca gcgacactgc tattttcttc ggcgaagata tgcttacagg ctttaaggtc
    14821 gttaagccat tttgcggtgg aaggccacat cgctctggcg cgctcagcgc ggcgtttgcc
    14881 taaatggagc tcgccaacgg caagataggc aataattccg actaacggca gaatgtaaat
    14941 aatcaacagc caggccatcg cggagggaac tgcgcgtcgt ttcattagaa tgcgtaaagt
    15001 tacgcctgca atgagcaacc agtatcccag aatggccaac caactcacca acgtataaac
    15061 ggttgtcata gattagaaat ccttttgaaa gcgcattgtt atgagtttac gcatatggat
    15121 tcatctggca aataaaaacg agggaaaagc actggtcagc gtcaggggcg ggggtataat
    15181 gaccattctg ttgttgcata gagtagttaa catgaagcgg agtagaacgg aagtggggcg
    15241 ctggcgcatg cagcgtcagg ctagccgacg taaatcgcgt tggcttgagg ggcagtcgcg
    15301 ccgaaatatg cgtatccaca gcatcaggaa gtgcattcta aacaaacagc gtaactcgtt
    15361 attgtttgcg atctacaata tctaaatgta ctgggcacca ttgcggtgcc caataagttt
    15421 actcttccgt ctttaaactc tatttttgcg ccgattcttt actgtcagct ttcgtttctt
    15481 gttcatcgtt atcgctgaaa atgccatgac cggagttcaa caacattgaa acgagcatat
    15541 cattattaat ctcttcacca tttaaaactc gcgccagaat ttcgctgcca aacagttgtg
    15601 gtgagagaat gatatccgga tgtaccatct taatcttatt caggtttttg ctatcactga
    15661 cggcaagaac tgttttgaca tcactgctca tatcttttgc cgagagtaca acaaacgcgt
    15721 tatctgcatc gttatcactc agcgccagaa tggcccggca acgatcgatt cccgctttct
    15781 ttaacactga actgtcatta ctgtcaccgg ggataacatc ggcgttatcg cctaagcgtt
    15841 gctcaagttg cttgatatca tcttcaggca agttgctgat aaccgttacg ttttgtccgc
    15901 gttgattcag ttgcagaatc gtattgatgg cgagaatcga atgtccgcaa acaataaaat
    15961 gatctttacg atgcattgta tgattgtttc cttttacaag tttgttgaat cccccgcgga
    16021 taagcggacc aaaaattgag gtcatagatg tggcaaaaac ggtaatgccg gaaataatga
    16081 ccgaaatagt gaacaatcgt gctgattcag aaacagggac aatatcgcca tagccgacgg
    16141 ttgacatggt ttctatcgaa aaatagaacg cggtcatcaa actttctatt cgcggattaa
    16201 aaccttcgct taaataaagc gcaccgtaag tggagtaaaa cagtaacgtc gtgaaactaa
    16261 taaatgcgaa aattgtcccg gctgctgcgc tactgtggga gaagtctttg ctcagtatca
    16321 gcaaaaacac cagcgtaaaa atgcaaaatc caatactaaa tttcagccag ggataaaaat
    16381 gcagagtgta aattagcgct atcaacaaca aaatgatact gattgcccat gcgagctttg
    16441 cccggaacag taagccaatg gagttcagga caagaaatac gccgagcata aatagtgggg
    16501 cgtttgccag caaggagaga tccagctctg aaaatgcttt gatatggaaa atatcaagca
    16561 aattgaccga cataccatag attgttttaa aaataagcaa tccatttaaa aagacggcca
    16621 gcgcgagaat gtcgtgccgt agggtcaccc ataactttgt tgctgtttgt ttgaatgtag
    16681 tccagtgact cactgatacc tctgtaacca caattttgtt taattatctc aacgtgcaca
    16741 ttttctgaac atacatgcag ctcgtgaatg tgttaaacaa tagtagatga ctttatccgc
    16801 agtaatcaaa ggttttgagt gagcaactct gcgtcaggaa agggcatttt cctgaatatg
    16861 ttcacatcat ataaagaaat acagataaag ttattatctg cttgtggtgg tgaatgcact
    16921 gaccgaccta taaggaaagg ccaaacaaga acacggttgc aaaaaccgtg cccttaaata
    16981 ttgaatttct attcagaaca ctttcttaaa tggtttcact gaaacgtgtt catagactcc
    17041 tgccgctacg tacgggtcag catcggccca ggcctgagct gcttccagcg actcaaattc
    17101 agcaataacg gttgagccag taaatcccgc agcccctgga tcgttactgt ctaccgctgg
    17161 cattggaccg gcggtcaaca aacgaccttc atcatgcagt aactgtaaac gtgctagatg
    17221 tgccggacga acggaaaggc gtttttcgag gctatcagct ttgtcttgag cgtaaataac
    17281 atacaacaca ggcacaactc cttgttcggg aaagttgtaa agtacgttat ttgaaagggc
    17341 gaagatctgc aacggaaaga tgatgtcttt gttaagacca tgcataaagt aaggtcaatt
    17401 acgccaaaaa tgacattttc actgatcctg atcgtcttgc cttattgaat atgattgcta
    17461 tttgcattta aaatcggggc ctggtttttc tactgaaatg attatgactt caatgaccct
    17521 tgatttacct cgccgcttcc cctggccgac gttactttcg gtctgcattc atggtgctgt
    17581 tgtggcgggt ttgctctata cctcggtaca tcaggttatt gaactacctg cgcctgcgca
    17641 gccgatttct gtcacgatgg ttgcgcctgc tgatcttgaa ccgccacaag ccgttcaacc
    17701 accaccggag ccggtggtag agccagaacc ggaacctgag ccgatccctg aaccgccaaa
    17761 agaagctccg gtggtcattg aaaagccgaa gccgaaacca aagccaaaac cgaagccggt
    17821 gaaaaaggtg gagcagccaa aacgcgatgt caaacccgta gagtcgcgtc cggcatcacc
    17881 gtttgaaaat acggcacccg cgcgcccgac atcaagtacg gcaacggctg caaccagcaa
    17941 gccggttacc agtgtggctt caggaccacg cgcattaagc cgtaatcagc cgcagtatcc
    18001 ggcacgagca caggcattgc gcattgaagg gcaggttaaa gttaaatttg atgtcacgcc
    18061 agatggtcgc gtggataacg tacaaatcct ctcagccaag cctgcgaaca tgtttgagcg
    18121 tgaagtgaaa aatgcgatgc gcagatggcg ttatgagccg ggtaagccag gcagtgggat
    18181 tgtggtgaat atcctgttta aaattaacgg cactaccgaa attcagtaag cataaagtca
    18241 aaagcctccg accggaggct tttgattatt actcaacggg taaggcgcga ggttttcctt
    18301 cgggatcaac cgcgacatac ttaaataatg cttctgttgc tttatagcgt tgcccgattg
    18361 gttctgacgc cacttttttc acccacactt caatattaat gctgactgat gtcgtccctt
    18421 tctggacaca gcgtgcatag cagcacacca catcgccgac cgcaaccggc cgtaagaaag
    18481 tcattccttc aacccgcacg gtcactacac gaccgtgggc aatttctttc gccagaatag
    18541 cgccgccaat atccatttgt gacattaacc aaccaccaaa gatgtcacca ttggcattgg
    18601 tatcggcggg catggctaaa gtacgtaaaa caagatcgcc ctgagggacg ttatgtgctg
    18661 tagacatggt aaaaccgact taaaaggaaa atcacaggcg cgatgctact atgattttcc
    18721 tgaggagaac agaggagata cagcgccagc cccgaaggac tggcagtctg gttaggattt
    18781 atcttcctgc ggcatgtggc ggtagatata gataccgctt aacaatgtga agattaaggt
    18841 aagggcggtc aggccaaaga ctttaaagtt gacccaaata ttttgcggca gccagaatgc
    18901 gatgtagatg tttgccaggc cgcaaaggat aaagaaaaca gcccaggcca gattcagctt
    18961 cgaccatacc gattgcggca gggtgagttc tttacccagc atccgctgaa ttagcggctt
    19021 tttcatcacc cattgactga ctaacagggc acccgcaaac agggcataaa tgacagtaac
    19081 cttccattta ataaactcat cattgtgaaa gaacagcgtc aagccaccga agacgaccac
    19141 cagaacaaaa gtgatcaggg ccatcttctc aaccttacga aagcgaaccc agctatagat
    19201 aagcacaatc gccgtggcga cgatcagcgc cgcagtagcc gcatagatgt cataaatctt
    19261 gtaaaacgcg aaaaagacaa ccagcggtaa aaaatcaaga aactgcttca ttttatgatt
    19321 ccgtaatcaa atgcttaagg ttattggcga atcaacatat acaggcggaa cagatagatg
    19381 agcaatacgg ctgaaatcag gttgctcaag gtgttcgcca gtacggcacc aatttccggg
    19441 gttaatgcgg caaaagaaga ggcaaaaagc agcaacagtg tttttgccag caaccagctc
    19501 agtactgcgg gtgccaccag acgcatattc gcccatgtca gccgcatact gctacgcatc
    19561 gaggcaaaaa cgcccatttt gtcctgtacc agcatcaccg gtgccagagc cagtaaaatg
    19621 gccatgataa ttcccggaac gaccaccagc atgatgccaa tctgtactaa aagggtagtc
    19681 agaaaaatca gaataaataa ctttggcaat atcggcgcac tggcaccaat agctcgcagc
    19741 gcactgactc tctgacccgc agacaccagc tggataatta atattacgcc cccggcgaga
    19801 atggcgttac cgattaatcc tgaaaaagtg gacgccgctg aagcctgcag caaaatttgt
    19861 tgctgttccg gtgacatatt ctgaaccagg tcgaacaacc cactactgcc gctaacgggt
    19921 acgccgtcat tgagctgcgc aagctgtgca tcactgggtg agaaaacatg ccctaacacc
    19981 actgtgataa acgcacatag caacgatacc aacagaatgg tcataaattg attacggaag
    20041 aaatttccgg tgtcacggta tacggactgc gccgtgatag acatgcactc tccttgagtt
    20101 ttatgcaggt gttaattagc gggcaattgt accctggtta agccccgggt ggcagcatca
    20161 ggtcttgtat ggaaaagcat atctttgtaa agcggaggta attgctggcc ttcaggcgtg
    20221 ggtaaaccgc tgcaagtggc gagcgagtta atatttgcgt agcgaaatat ataaaaattg
    20281 atttaaatca cattaaccag gattttcaat gcaacttcta aattaatcta gatcaataaa
    20341 gggtgaatta ccatatgtaa tgtgatctgt gtaggatcat ttgttacccc aatgtgggta
    20401 tattcgtcac gtttttataa ccataacgac ggagcggata tgaaaaagtt aacagtggcg
    20461 gctttggcag taacaactct tctctctggc agtgcctttg cgcatgaagc aggcgaattt
    20521 tttatgcgtg ctggttctgc aaccgtacgt ccaacagaag gtgctggtgg tacgttagga
    20581 agtttgggtg gattcagcgt gaccaataac actcaactgg gcctgacgtt tacttatatg
    20641 gcgaccgaca acattggtgt ggaattactg gcggcatcgc cgtttcgtca taaagttggc
    20701 acagccacaa ccggggatat tgcgacagtc catcatttac cgccaacact gatggcacaa
    20761 tggtattttg gcgattctgg cagtaaattc cgtccttaca ttggtgcggg tattaactac
    20821 accacctttt ttaataatga cttcaatgac accggtgaag gtcttggttt atctgacctt
    20881 agtctgaagg attcatgggg cgtggcgggg caagtaggcc tggattatct catcaaccgt
    20941 gactggttgc tgaatatgtc agtctggtac atggatatcg ataccacggc taagtacaaa
    21001 tctggtgtta ctaccgtaaa agactcggta cgactggatc cgtgggtgtt tatgttctcc
    21061 gcaggatatc gtttttaatt ttctctgcaa aacctctgca aaacccctct gcaaaactgg
    21121 tcatcaaatg accagttttt tccattcctt accgcgtgcg tcgttgtaaa tatcggtcat
    21181 tttttgattc gaatggccca gcaaaatttt ggtatcaacc ccctgctctc tgaacaatcg
    21241 ctctgataaa gatctctgct catggaaaga gggtggggtg ccattagcac gccagttgta
    21301 atccacagaa tcccgggctt ttttaaatgc aacggttaat gttgctggct taaccatccc
    21361 gccgcgctta gctgtccctt tcgcgtgatg gtggtgcaat agccacggac taagaacgca
    21421 atcgcggcag gatgacacca catcatctag ggtgagattt aatttatcgc aacgcagagc
    21481 cagagggatg gcaatccggg ttcctgtttt ttgctgttcg acatgaagat aaccatcccg
    21541 gatatccgaa aattgcattt tgcaaatatc tgaaaggcgc tggcctgtca tcagtgccag
    21601 cagcataccg cgctgtaaaa agtaaccatc cttttccgct gcgttataaa tcatcatcca
    21661 ctcatcaaaa gtcagtcgct gtcttgatat ccgcacctgc ggtttttttg ccgattctgc
    21721 agggttaaag cctggcggga catcgcccgt ttgctgagct tcccggaaaa catcgatcag
    21781 taccttcctg aaaatttgtc ccattctgtt atgtcctctg gccttgtact cttccagtac
    21841 tgataccaca tcttttacgg ttatggcatc taacggtctg gtgccaaaac gttcatcaaa
    21901 taccctgaga ggggccgctt tctgtttcag cgtgttgagt ttgatctcgc cgttttcata
    21961 tctttcctgt tgaatttttc tgtaattatt cagaaaaatg gtaacggttg atgaaccgcc
    22021 ggtatcacta ataattttct cctgcagact gagcatttgt tccatttgct gccgggcaag
    22081 acggctgttc gcttctgctg caatagtttc tgccagtttc tggtcaatac tgccgagacc
    22141 gtgatttttg cctgttatgg gatgcctgta acgccagtaa actttgttat ttcttttgtc
    22201 aaaatacgga gataatcccg gaacattggt tttatatttt cgcgggcgcg ccatcttcca
    22261 gtatcctctt caaagcaggg tgatctgtgg cgatcacctc cggcttgttt accattccga
    22321 caaagcgagc ttgcggatcc actcgccagc gtcttccaac ttttttgggg agaggaaata
    22381 tcattccggc tttagcgtat ttacttaacg tactcggagt tgggaccggt tcactgaatt
    22441 cctcttttgc ccactcagtg agcagaataa gtcttgccat gagcgtcgtt cgctaatcat
    22501 ggtcgccgcc actatagctg gtgggcaacg accggggttg aacattaaaa atcagcctga
    22561 ttcgggatca gtttttgcca gataactgaa acgtattttg cctggtaacg ggcgtcatca
    22621 agtgcattat ggcgctcacc ttcgaatgga atagccgttc tggcatcgaa gtctatggct
    22681 ttccccagct caacgattgt gcgtacatcg cgatcgttgt agtaacgcca tgggcagggg
    22741 atcccctgcc gttcgtatga acggcgcaaa atcgtgtttt cgaagttggc tccatttccc
    22801 cagacctgaa caaaaaattc accggagttt tcgtcgataa attcccgcaa ttgtaacagt
    22861 gcatcatcta acgggatttc atcggtcata atggcagact gcgcttcacg tgattgcttc
    22921 agccaccttt taatgacgtc acgatcaatg actccgccag cagtttccag atcgatagtc
    22981 ttactaaatt ccggtcccat atctccggtt tgcggatcga aaaatattgc atctattgag
    23041 ataatcgggg catcaggatt ttttcccatg gtttcaaggt caatcatcag atggtgccac
    23101 aacctgctgg tggatgtgct tttacgatga ctgttcacct taattaaggg atttgctgtc
    23161 tcgcctattt cattattgtc attggcatgt tgatcgcctt cggtgcactc cttgttcggg
    23221 agtccggcat tttctatttc ctctggatct ttttcccggg cttcatcctg gctttcttcg
    23281 ttgaatgtct cctggtaggt tgcgtcaccc atcactgcgc cacaatcagg gcagttacca
    23341 ccaccagtct gattgcatgc ggtacaaact ttttcctctt cctgttgcac gactggttca
    23401 ggttgtttcg tttctggctc gttttgtaac gcattttggc tgttttgttc cgctttttgg
    23461 tcgtactgtt ccgtttctga ctggttctgg tgcacagaat cgcgggtttc aatccccttc
    23521 acccatttcg gatcattcgg gtcgctaatc ccttcaacaa attcaccacg tgatgcagcg
    23581 agcaacttat tagcgtcagg ctggctgata ctggctgcct gcataatttt gtttacttcg
    23641 tcagcggtaa cttttaccag gtctggttgt gcggtcgtgt cagatgcatc agtattttgt
    23701 tgtgaacctg tgtatgtgcc gtttttgcgg gcaaaatatt cttctttcgt gatttcagtt
    23761 gccccggcag ccagcgcctt atccagacca gaaagtttgt ttgcgcgacc gtatttttcg
    23821 ccatccttgt cggtgaagag gaagtagaac ggcccctcac gctctacaga tggttcgact
    23881 tccactttgc attcggtttt ttcgttgtcc ggaattgccg tttccactgc atcagtttct
    23941 ggtactggcg acgagagagt atcagttgcg ctctgatttc ttccttcatc ttcaaacacg
    24001 ccctttgtag tcaggtattc agtaatgtat ttgttcagtg ccacagggtc tttgtgaatg
    24061 tcgatcggac gttcacggac aaggccaaaa atagtctggc ggtcgtagcg aagggcatca
    24121 ggctgtttgc gcattgatgc cgagatacgc ttccagtctt cgcggtcgtt gtcgataact
    24181 tcattttttg cccagcgatg gatgctgccg tcaatgtttc cggcatccac atcaccaggc
    24241 cagagagcgt aggccagttc gtcatccagt gttttccatg tctgcttgta ttcgcgatga
    24301 atggcagcaa tgaccgggct gatttttcct gttgaatttt cagtgtactg ttgattggct
    24361 ctggcgcggg cgagatcaac aacagacgtg tattttccgg tttccttgcg ttcaccttca
    24421 cgacgttttt tccagatgcg catctctgcc tgaatttcgg gccatttggc accaggctta
    24481 catttatgct taacccaccc gatggcatgc agcttaagct ccggatacat ggcgttaact
    24541 tctggcattt tcatcaacgc ttcaacgata tgtccgtcga atgttgccat gtcttcctgc
    24601 aacaattcct gtgcgctaat aaccatatca acggtgatgt tttcacatgt gtcgaactta
    24661 accatgacag cgttctgtac ttcaggggcc agcttgtcaa aagtgacgtt catcggatcg
    24721 gattcagtct caaccgggac aaaggaagca gactcctcat cccagcggtt ttcctgcata
    24781 tattcagcat cccaggaatc gagggcaggg cggggtatac cgggtttatc ctcgcagaca
    24841 agaaatttat aagcgcagtc ctgagcagcc ggataatgtt ccaggaattg ccagtgaaat
    24901 tttgcgcggg cgcgacgttc atcaccggct tcaatggcag tggctacagc gacggcacct
    24961 tcttccttta ttgcctgttc gtccggaatg gcggcgcaaa taaagacttt actcattttg
    25021 ttttacctca ttacagattt aagggtgaac aaatccctgc cattgctggc atataagaat
    25081 gaaaccggat atttattacg gaactgtttt aaagacctgc cgggatttcg ttattatcct
    25141 ggtgaataac tttatcgacc gggtaacagt taccgggaat tttctgttcg gttgctgcag
    25201 tcacacactc ctgcattgtc ctgtgaacac tgactgcaat atcaactggc tctccggaaa
    25261 caagaaaaac tgtcagaaca agtgcaaatg ctgtattcat tgccagcatc ctttttgtat
    25321 cggacgtaaa cgggccagca ttgaaagaat gcatatttta tttaatagct cccgttcgtg
    25381 ttttctcttg ttaatggcat cttcagtaaa tacagggtta ctgatattga caccaatttc
    25441 aaaacaacct tcagacgtat taacgtttgg taataacgtt tccattatcg cgtcctcaac
    25501 aatgaatttt gtgatgcggt gcctggtgcc tccaggtgac gttaaccagt taacaattaa
    25561 cgccggatac agagaatcca cccataacac tgtttttggt tttaactgtt ccgcgtgcgc
    25621 tcagccgcat tcaccacatc acaaaattca ctttaaaaag ggcggcagag cagtcacgga
    25681 gtaaaactga taccgccaaa cgtcaccaga aaattgataa cagagggcgt tgcagcggag
    25741 ttgtcactta agcgtatggt caacctgaca acccggtgtc ctcaacggag gaaggaataa
    25801 ccccgccata cttaccgccg cgccatttcg cggagtgcca caaccggaag cgcacggtcg
    25861 aactaaattt aacgacaccg tacagagaga ccaatttcgc cgtgcgcttt cgctttatgc
    25921 cctgactttt cagggacata tcctttcagt aaactgtcag tgccggatgt tcacccgtgt
    25981 ccggcgcacg cactccacct gacccgtgga gaactcctta attaccaacc ttagcttcgt
    26041 tggttagcta ttaacgcggg tatgtaacca ttctggcaat gcttaatgcc gctgcttttt
    26101 ccagcctggt gatatcctgc tccagagcgg acagattttc agcctgctta gtcctggctt
    26161 cattggccca tttcagatcc tgcgctgcat taattttctg gcgcatccac tcataaagtt
    26221 catcatcggt atagtctggc gcgatgatga cgggttctcg tttctgcata ctgattcctc
    26281 gcggtgctgc ttcgcttatc agccgttaga ttttgccgag ctggaaagcg cctgtttaaa
    26341 ctcactgaag ctgagagctt cttcgccttc ggcaaggcct tcgaagtatt cttcgtaagc
    26401 cttttccatg attgtgtcga aatccatatc actcacctga gtttctttcc agccagcgac
    26461 gggcaccatt ttcggtttta aacgttttgc ttttggtata cgtcattgcg gtgaacgtgc
    26521 cgtcctggtt ggggaacacg ccacatacca gagattcgct gttgccaaga tcgatagtat
    26581 ccatgctgac ctcatttccc cttaacgccg ggggagcgga acaaaaacct gctgcatagt
    26641 tattaaagtt gaaccctgcc gtcatgttct tacgcctcgg gctggctact taccccctga
    26701 ccactgcttg gtaactcgaa gtattgcccg gcgttctgtg gggcggggtg ggttggtatg
    26761 ttgttaaggt aacaagagtt acctttcgag tcaatacaat gttgcaaaag gtacatttga
    26821 gggcataaaa aacccgcaat gaatgcgggt tctgactcag tctaagtatt gatgtatttg
    26881 tgaaacttta cctttaatgg tgtaaccacc attcagttcg atgggtttgt aaagcggatt
    26941 cagtgacaac agatagatgt ttggtccgtc aatcgcaact ttttttagtg ttacgtttgg
    27001 cgttccttcc aattggatta agattatttt tcccaccagt tctctaatgt tacttgagca
    27061 tggtgtgatc agcacggtag atccgtcggg gatggttggg aggccgttag agtttgtcat
    27121 cgcatctccc tcaacatgca ataaaaaaga gttttcagcg gtttttgtca tgacatcaac
    27181 ccagttctta ataccaggaa tcttggttac tggacaactc atatcccaat aaccagcctg
    27241 ttcccacgtt aaaacgggca accgggcgat gttgtcacta atgtaagggt actgattcag
    27301 acgcagatca tcggttttat cgtgaccgtc ctttccataa agaatccatt caggagattt
    27361 ggaaagcaat tttgacagta gatacaaatt ctcaccgtca ggttttgaag agccattttc
    27421 ccattttgtt acggatacac gagatatgcc gattgctttc gcaacctgct gttgggttaa
    27481 tccaacgtct tttcgacgat tccgaatacg ttcgctgata gtgtttttca tgtaaccaat
    27541 gttactacca agtgatgttg ctatggttga cattgttatg taactattgt tacccttctg
    27601 ctcgaaataa caggagagtt ttatgttcaa agatgatgtt ctgcgctatt tcaaaaaaaa
    27661 gcgactagta gctgaggctc ttggaatttc acatgtggct gttgtgcggt ggaaagcagt
    27721 tattcccaaa cttcgcgcaa tggaactgga tgaaattact aacggtgaat tgaaatacaa
    27781 cccagaactt tacaagaagc aggatagcac ctcgaacgaa ggaaagaatg attcatgaaa
    27841 atcaagcatg aacacatccg catggcgatg aatgcctggg cgcatccgga cggcgaaaaa
    27901 gtgccggctg cgaaaattac caaagcgtat ttcgagctgg gaatgacgtt cccggaactg
    27961 tatgacgaca gccatccgga agccctggcc cgtaataccc agaaaatttt ccgttggctg
    28021 gataaagaca cccctgatgc tgttgaaaaa atgcaggctc tgttaccggc gatcgaaaag
    28081 gcgatgccgc ctttgctggt ggcccgtatg cgcagccaca gttctgaata ttaccgtgag
    28141 atcgtcgaac ggcgggatcg gctggtgaag gatgtcgatg attttgttgc gtcagcggtt
    28201 gttttgtatg accagatgaa tcgcggcggc ccggcaggga atgctgtggt gatgcactaa
    28261 aagcacggtg ttcgggggtt ttatgagcag caagcttcat ggtcttgtct gggaagggtg
    28321 cgccttcacc ggcatgatct tatccagggt ggcggttatg gcccgtcttg cagactacag
    28381 caatgacgag ggcgtgtcat ggcctgccat tgaaactatc cggcgtcaga tcggtgcaag
    28441 aagtgaatcc acagtgaaat cggctattgc agaactggcg aaagagggct ggctgacgaa
    28501 ggaagagcgt aaggtcggtg ggcgtaatgt aagcaatatc tatcggctta atgtggaaaa
    28561 actcgaagca gctgcggcgg cggcgcgtga gtcatataaa ccgaaaagaa aaattagccc
    28621 ggcaaaaaat gacccgttaa cagttgaccc gtcaaatatt gacccctcaa cggttgaccc
    28681 gtcaaatttt gatggatcaa ctgttgataa aaaactgccg attagggggc cgatgattga
    28741 ccccgatccg tcagtattaa aacctgatcc gtcagataaa agatcttctt gtccggacgc
    28801 ttcgcaaccg gacccgcaga cggctgaaca ggatttttta acccgacacc ctgacgcggt
    28861 tgtgttcagt gcgaaaaaac gccagtgggg aagtcaggaa gatttggtgt gcgcacagtg
    28921 gatctgggga cgaatcgtga gtctttacga gcaggcggcc agctatgatg gcgagatcac
    28981 tagaccgaaa gaacccaact ggacagcatg ggccaatgac gttcgcacaa tgcggatgct
    29041 ggatggcaga actcacagac aaatttgtga aatgtttggg cgtctccagc gggattcgtt
    29101 ctgggtaaaa aacatcatga gtccggcaaa actccgggaa aaatgggatg aactggttat
    29161 ccgcctgggg cgttcgcctg cgcagcgttg cgtgaatcac atttctgaac cggacactga
    29221 aataccgccg ggattcaggg ggtgacgtgt catgaaaaac attgcggcag ttggggttct
    29281 tgaacgtatt cgcagacttg caccacaggg gtcggttcca ccgtaccgga cggtggagga
    29341 gtggcgggaa tggcaacttg ctgaaggacg aaaacgcagc gaggagatta accgccagaa
    29401 tcgccagttg cgggtggaaa aaatcctgaa tcgttcgggc atccagcctc tgcacagcaa
    29461 atgctcgttt gcaaattatc aggtgcagaa cgacgggcaa aaatacgcgc tgagccaggc
    29521 caaatccata gctgacgaac tgatgaccgg gtgcacgaat tttgtgttca gcggtaaaac
    29581 cggcaccggg aaaaatcacc ttgcagcggc gatgggcaac cggctgatgg tgaaggggcg
    29641 cagcgtgatt atcgtcaccg tgtctgacgt catgagcgtg ttgcatgaca gctacgacaa
    29701 cggcaaatcc ggggaaaaat ttttacagga gctttgcggg gttgatttgc tggtcctgga
    29761 tgaaataggc gttcagcggg agacgaaaaa cgagcaggtg gtattgcacc agataattga
    29821 tcgccggaca gcatcactgt gcagtgtcgg gatgttaaca aacctgaatc atgccgcaat
    29881 gagtacgctt cttggtgaga ggattatgga ccgcatgacc atgaacggtg gtcgatgggt
    29941 gacgtttaac tgggatagct ggcgtccaaa tgtcagcaat atgagggttg tgaagtaatt
    30001 ttgtccggag gaaattttaa tggaaaccgt atctgacgca ctgaaagcac tgaaaaaagc
    30061 ctcttcacat gtggtggcag ctcgccttgg aatcagtcgt gaagaggctg tcaacgagct
    30121 gtgggaactc aaaagaaaag gcgtcgttga taaaactggt cacacctggt ttttggctgg
    30181 cgaaggtgaa tcccgggtaa ccgaagagcg gccagtaaaa tctgaagcac aggatatgct
    30241 gaccggggag gtcgaacaaa aagttaccgc agacatgatg attgagttta tcggtcagga
    30301 tggggctaaa acgtgtgagg aactggcggg taagttcggt gtcagtactc gcaaggttgc
    30361 ttccacgctg gcggtggtaa ccgcaacggg gcggctggca cgcgttaatc agaacggtaa
    30421 atttcgttac tgcatgccgg gcgataattt accagcagag ccgaaagccg cgctggtaac
    30481 ggaaagtgat ggtaaggcct ttcctcagcc agcaggtgct gcgttaccag tccgggaagc
    30541 cgcaacacag gaagaaatta aaacagaaac tgtggcggac attgtgcagc cgttgccatc
    30601 gtttaccgaa acgcaagcag atgagctgat ttttccgtcc cttcgcaggg caaacctggc
    30661 gctgcgcagg gcgaaaagtg atgttcagaa gtgggagcga gtctgcgccg cgctgcggga
    30721 gctgaacaag caccgggata ttgttcgaca gattactgat tcttcccgcc gtgttgtatc
    30781 ggaaaagtga ttgccggagg cgcttatggc aaaagtattt acacaagaag agcgggaaaa
    30841 aattaaaggg caggttgttg aacttgtacg tctgagcggt cgcgagacgt tgcggcaact
    30901 ggaagccaag acaggtgcga caagatatct gatgagtgtt ctcgccagag agctggttgc
    30961 cagtggcgat gtatacaact ctggttacgg gttattcccg tctgaacagg cgcgtaagga
    31021 ctggcaaaat gctcgcaaaa aactctcaag ggcaaaggtg aagaaacctg cagtggttga
    31081 tccggacctt atctggtcgt taccagacgg cgaaatacgc cgctacgaca ggcgcctgaa
    31141 tataatctgt cgcgagtgcc ggaagagcga agctatgcag cgtgtactgg cattttatca
    31201 aggaaatgtt aggtatttta gacgttacta gattaaagag cattagttca gatgtgaatt
    31261 gacattttca tggcgcaggg tagagccagc gtggttgtcc gctttgcgtc aaaaccagat
    31321 attaccagat ttagacatat attcccgata gccctgctct gatgctacac tctgtgctat
    31381 tttcatgacc ccaataaaaa tatttatgac tattgctgat ttcaaacggc ctaaattgga
    31441 gctcccaaac ggggcaaaca aactactact gcactcttgc tgtgctccat gttccggtga
    31501 agtgatggag gcgcttcagg cctcgggaat cgactacacc atctttttct acaacccgaa
    31561 cattcatcct cagaaagagt atttaattcg taaggatgaa aatattcgct ttgctgaaca
    31621 acacggcgtg ccgtttatcg atgctgatta cgacaccgac aactggtttg aacgtgccaa
    31681 aggaatggaa tgggagcctg agagggggat ccgttgtacc atgtgttttg acatgcgttt
    31741 tgagcggaca gcgttgtacg ctgctgaaaa tggtttcagt gtgatcagca gttcactggg
    31801 catttcacgc tggaaaaata tgcagcaggt taacgagtgt gggcggcgag ctgttgcgca
    31861 ttatccgggt atggtgtact gggattataa ctggcgcaag cagggcggct cgtcccgtat
    31921 gattgaaatc agcaagcgcg aaaaattcta tcagcaggaa tattgtggct gtgtgtattc
    31981 tctgcgcgat accaatctac accgcaaatc tcagggacgc cctcttatca aaattggcca
    32041 actccactac ggaaaagaag agaaggagtg attttatgga tcacctttct gattgatttc
    32101 atattggcga ggtgacgtga gttaagtaga atggctgcgg gtgcttgagg ctatctgtct
    32161 caggcatgaa cactgaaagg cagatagaga aaagccccag ttaacatttc gcgtcctgca
    32221 agacgcttaa cattaatctg aggcccaatc tatgtctcac aaatgtaggt tagcctctta
    32281 cgtgccgaaa ggcaagggga agcaggctat gaagcagcaa aaggcgatgt taatcgccct
    32341 gatcgtcatc tgtttaaccg tcatagtgac ggcactggta acgaggaaag acctctgcga
    32401 ggtacgactc cgaaccggcc agacggaggt cgctgtcttc acagcttacg aacctgagga
    32461 gtaagagacc cggcggggga gaaatccctc gccacctctg atgtgtcagg catcctcaac
    32521 gcacccgcac ttaacccggt tcggcgggtt ttgttttttt ctggcattct ggtttacaat
    32581 tcgcacgtca gcctgaacac ctgacacctg ctgcgccagc agagaaaaca gatggcgcac
    32641 aaaaccaaat ttcacaattc tgataccgac cttgccatcc ggcatgggcg gcgttcacac
    32701 gcatttaaaa ccgactggta ccaacaccca ccatgtactg aagaacaggc cgaatggcta
    32761 attcataact accgcagacg cggatacgag attaagaaag ccctcagcct cgattatcgt
    32821 cactggataa tctccgtcag gcttccttac tctgaacgcc caccgcgtcc gtcccgcaca
    32881 ttccagcaac gcatctggag gtaacgtgcg ggtattactt cgacctgttc tggtaccgga
    32941 actcgggctg gtgatcgtta agccgggccg tgaatccatg ccggtattcc acaatacccg
    33001 ggtactggtg gagccggaac cgaaaagcat gcgtaatctg ccgtccgggg tcgttcctgc
    33061 cgttcgccag ccgctggcgg aggataaatc attactgcca tttttcagcg acgaacgagt
    33121 gattcgtgct gctggtggcg ctggcgcatt gtctgactgg ttactgcgcc atgttaaatc
    33181 ctgccagtgg ccacacggcg attatcacca cagtgaaacc gtcattcacc gttatggtac
    33241 cggcgcaatg gtgttgtgct ggcactgcga caaccagctg cgcgaccaga cctccgaatc
    33301 actcgggcaa cttgctcacc aaaacctgtt tgcatggatg attgacgtca tacgccatgc
    33361 aatgaatggc tcgcaggaac gggaattatc gctggctgaa ttatcctggt gggcggtccg
    33421 caatcaggtg gcggacgcgc taccggaagc ggtattacgt cgttcgctgg ggttgcgtgc
    33481 ggaaaaaatc cgctcaatgt accgtgaaag cgacatcgta ccgggagagc agaccgccac
    33541 cagcatactg aagcagcgca caaaaaatct tgcgccgctg cctcacgccc accagcaaaa
    33601 cccgccacag gaaaagacgg tggtcagcat tgccgttgat ccggagtcac cggctcagta
    33661 tctccagcgc cagaaatcac aacgggaaga gatgcctgta tacacgcgtt gggtaaaaac
    33721 gcagaaatgc atgacgtgtg gcaatcaggc agatgatccg catcacatca ttggtcatgg
    33781 actgggaggg atgggaacaa aggctgatga tttgtttgtt attccgctgt gccgtaaatg
    33841 ccatagcgaa ctacacgccg gggtaaaaga ttttgaagaa aaacacggca gccagctgtt
    33901 gttgctgatt cgttttttaa tgcacgcgag aaattcgggt gttctgaagt ggaaagcata
    33961 aatgactgaa cgcatagaat ttgttttgcc ttacccgcca acggtgaaca cttactggcg
    34021 tcgtcgtggc agcacatatt ttgtatcaaa agccggggag cgttatcgcc gggcagtggc
    34081 gcttattgtt cgccagcagc ggctgaaatt aagcctgtcc ggaaggttgg caataaaaat
    34141 tattgcagaa ccaccggata agcgccgccg tgatctggac aatattctga aagcgccgct
    34201 ggatgcgctg acgcatgcgg ggttgctaat ggacgatgag cagtttgatg aaatcaatat
    34261 cgttcgtggt cagccagtat ctggtggacg tctgggggtg aagatttacc ccataatgca
    34321 tgaagagcag gtcaaaaaat gaaactggaa gatttaccga aatactactc cccaaaatcc
    34381 cccggcctga ctgatgcatc ggcctcaacg tcgaaagatg cgctgagtat cactgatgtg
    34441 atggccgcgc agggcatgac acagaatcgg gctgagatgg ggttttctgc gttcctgggg
    34501 aaaatgggca tcagtatgaa tgacagggcg cgggcaacag aattactggc agattatgca
    34561 ctcagtcggt gcgatcgtgt ggcggcgttg agaaaacttc cggcagaaat aaaaccggta
    34621 gtgatgcgca ttatggcttc gtacgctttt gaggattatg cccgcagcgc agcgagtaaa
    34681 aagcagtgcc cctgttgccg aggggaaaaa tttattgaag gcgaagtttt tacaaacaag
    34741 gttcagtatc cggatggcaa gccgccagta tgggcaaagt gtacgaaagg tgtgtatccg
    34801 tcttactggg aagaatggaa aaaaattcgg gaggtggtga aagtttcttg tcctgaatgt
    34861 aaagggaagg gggagatttc cactgcctgt aaagactgcc gtgggcgtgg tgtcgccatt
    34921 catcgtgaag agtcggtaaa acgtggtatg cctgttatca gagactgcca gcgttgtggt
    34981 ggtcgtggct gtgaaagact accatcaacg gaggcattta atgccatatg caaagtgacg
    35041 agtgctatca cgcttgatac gtggaaaaaa tcagtgaaac gcttttacga tacgttggtg
    35101 gttcggtttg acattgaaga ggcatgggcg gagcggcagt taaagagggt aacgcgatag
    35161 tgttgttgat ttttcccgaa tctgtggtaa atttgctcta acgatgggcg ttttatgcct
    35221 gacgttagaa gattttttac accccgccgc ctggcgggtt ttttatgact gaaatcgcgt
    35281 cagtacagta aacgcgctgg tggcggtgaa tacctgtctt tcagcttgct ggctttttcg
    35341 acaagagtta ttggtgtgtc acgttaaccg gaaaagggaa aaagacatgc tgaaacagca
    35401 ggatatgaca gaaaccgcca gagtggtgtt taatgaatta agcgtcaccg aaccggcgac
    35461 agccggggag attgcgcaga atacttacct ttcacgcgaa cgctgccagt taatactgac
    35521 ccagctggtt atggcgggtc tggcagacta tcagttcggt tgttacagac gccttccgca
    35581 gtgaaggctt ttttatttgt ggtaaatggg cggctggtgg gtgttagggg cacccaccag
    35641 ccatctgctc atgcgttggg gtcacaagca aacctcaggc ccatctgctt tgcgcaaaag
    35701 cggtatgagc ctatcagaga agtgcttatt gatctatggc taatactgta aaaatatcca
    35761 gttgtgagtt aatcaacgcc gactgcctgg aatttatccg gtcgttaccc gaaaattctg
    35821 ttgacctgat agtcacggac ccgccgtact ttaaagtgaa gcctgagggc tgggataacc
    35881 agtggaaggg cgacgatgat tacctgaagt ggctggacca gtgtctggcg cagttctggc
    35941 gggtgctgaa acctgccgga agtctttacc tgttctgtgg tcatcgcctg gcatctgata
    36001 tcgaaatcat gatgcgtgaa cgcttcagtg tgctgaacca tattatctgg gcgaagccgt
    36061 ccggacgctg gaacggatgc aacaaggaaa gcctgcgggc gtatttcccc gccacagagc
    36121 gcattctgtt cgcggaacat tatcaggggc cgtatcgtcc gaaagatgcc gggtatgcgg
    36181 cgaagggcag tgcactgaaa cagcatgtga tggccccgct gatttcttac tttcgtgatg
    36241 cgcgcgcggc cctggggata acggcaaaac agattgcaga tgccacagga aagaaaaaca
    36301 tggtgtcgca ctggttcagt gccagtcagt ggcagctacc gaacgaaagc gattatctga
    36361 aattacagtc gctgtttgcc cgggtggcag aagagaaaca tcagcgcggt gaactggaaa
    36421 agccccacca ccagctggtg gatacgtata cgtcactgaa ccggcagtat gtggagctgc
    36481 agagtgaata taagcatctg cggcggtatt ttggtgtgac ggcgcaggtg ccgtacacgg
    36541 atgtgtggac acataaaccg gtgcagttct atcccgggaa acatccgtgc gaaaaaccgg
    36601 cagaaatgct gcagcagata atcagcgcaa gcagtcgtcc gggtgacctg gttgcagatt
    36661 tttttatggg ctcaggttca acggtaaaag cggcactggc gctcgggcgt cgtgcgattg
    36721 gcgttgagct ggagaccgga cgttttgagc agacagtcag ggaagttcag ggtttaatcg
    36781 tttgaaacgg atgagattgc agaattaatt acgcaccatt attattctgc tcccggccct
    36841 ttagctcagt ggtgagagcg agcgactcat aatcgccagg tcgctggttc aaatccagca
    36901 agggccacca tcacaaaccg ccattagctt atcaggaaga gcagacgaca cgataacagg
    36961 gttgttggtg cgggggcggg tccccgatgg cggtccatta tcggtattca gcgttgttag
    37021 ctcagccgga cagagcaatt gccttctaag caatcggtca ctggttcgaa tccagtacag
    37081 cgcgccatat tcattcttcc agattccttc cggcagagcc ttatactgaa atatacctgg
    37141 ctcaggatat tgttgaaaat attatatgtt tgtcaaaaat aaaagttctg ttaagtgttg
    37201 attgagtgtt tgttatacgg tctaatggtt ttttcagcat taaatattta tcattcatat
    37261 ggtgtgggta gagtgaatat tgatgaggcg tcggggtgtt tcatccttag gcagcgtatt
    37321 gatatagtca atgcagcacg agcaaaggcc ttcagccgtt tgacagtttt gttctgtact
    37381 cctgatcgtc tttcgggaag agacgttatt attctgaata gtgatgctat acagagggtt
    37441 tgcgatgagt tcatggtggc taattcagaa ttatttactc ttgttcagga gtacaacaga
    37501 atagccagga cctgtggtat ggatgaactt cggattactc atctggggta gatacatatc
    37561 tggattatca ccggttacgg taaaaagtga ttgcttactg tttttgtgaa tggcattgct
    37621 gcagccggat aatgtcagtg ctggctgacg gtgtgctggt ggcgggtgtg gtggttgttg
    37681 ctttcccgtt gctgaaaaag aaaacgccag actgttagcc gggtatcagt tagcgggaga
    37741 aatttttaaa tacttcacaa ttcaggcggt tgattgttgt ctggtttgcg gggagtttgt
    37801 taaaagaaac tggcatggtg aatccccctg tgcggagggg caatcagcga gtaggtatat
    37861 gggataatcg cggattcagg tgctggtact gaattcaccg ggaggcaccc ggcaccatgc
    37921 aatggcacat agcgccactc tccagcccct ctccggaggg gctgtttata ttgattttgt
    37981 cagatgtgag taaactcctt atggactttg ttgttttagt ccataaggac atatttgcag
    38041 agtgcaacgg ttattaaagc attcattcaa tacgttatct gtatttgtag ggcattcctg
    38101 gctgtttttg attaaattcc agaatgtttt attgaatggt actacgttgt aaatggt
//
LOCUS       DAPOXO010000045        37956 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.045, whole genome shotgun sequence.
ACCESSION   DAPOXO010000045 DAPOXO010000000
VERSION     DAPOXO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37956
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.045"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            270..896
                     /locus_tag="ROH59_002688"
     CDS             270..896
                     /locus_tag="ROH59_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HDX4805149.1"
                     /translation="MNPVDRPLLNIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKESQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
     gene            917..3019
                     /locus_tag="ROH59_002689"
     CDS             917..3019
                     /locus_tag="ROH59_002689"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HDX4805150.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPP
                     GNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFKAITGEDMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQR
                     LGLEDIAADLAAHNLLPA"
     gene            3032..3670
                     /locus_tag="ROH59_002690"
     CDS             3032..3670
                     /locus_tag="ROH59_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310406.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HDX4805151.1"
                     /translation="MNHQDELPLAKVSEIDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLENIKQNGDYADIACMTGSQDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            3734..4402
                     /locus_tag="ROH59_002691"
     CDS             3734..4402
                     /locus_tag="ROH59_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDX4805152.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVIDNDNGTQYHFFRQSCQHCEDAPCID
                     VCPTGASWRDEQGIVRVEKSQCIGCSYCIGVCPYQVRYLNPVTKVADKCDFCAETRLA
                     KGFPPICVSACPEHALIFGHEDSPEIQAWLQENKYYQYQLPGAGKPHLYRRFGQHLIK
                     KENV"
     gene            4399..5184
                     /locus_tag="ROH59_002692"
     CDS             4399..5184
                     /locus_tag="ROH59_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HDX4805153.1"
                     /translation="MNPSQHAEQFQSQLANYVPQFTPQFWPVWLIIAGLLLVGMWLVL
                     GLHALLRARGVKKSATDHSERIYLYSKAVRLWHWSNALLFVLLLASGLINHFALVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLDRAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYW
                     LLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            5188..6000
                     /locus_tag="ROH59_002693"
     CDS             5188..6000
                     /locus_tag="ROH59_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805154.1"
                     /translation="MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERLFCSQFVRSDDHARLGCCED
                     NARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGARARVAVTGNSSRISSAGDSGRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGCAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC"
     gene            complement(6012..7616)
                     /locus_tag="ROH59_002694"
     CDS             complement(6012..7616)
                     /locus_tag="ROH59_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HDX4805155.1"
                     /translation="MKTIAIVGAGPTGIYTLFSLLQQQTPLSISIFDQADEAGIGMPY
                     SDEENSKLMLANIASIEIPPIYCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILL
                     GEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNLNLPSETFDLAVI
                     ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFI
                     EDDKQHVTFHRDNANEKLNITLMSRTGILPEADFYCPIPYEPLHIITDQALNAEIQKG
                     EVGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEENL
                     QEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPS
                     ESIRRLLALREAGIIHILALGEDYEMEINESRTVLKTEDNSYSFDVFIDARGQRPLKV
                     KDIPFPGLREQLQKTGDEIPNVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGITA
                     CAEIGEAMARAVVKPASRARRRLSFD"
     gene            complement(7742..8047)
                     /locus_tag="ROH59_002695"
     CDS             complement(7742..8047)
                     /locus_tag="ROH59_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDX4805156.1"
                     /translation="MATLLQLHFSFNGPFGDTMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNVPLSQINQAKLA"
     gene            complement(8156..8232)
                     /locus_tag="ROH59_002696"
     tRNA            complement(8156..8232)
                     /locus_tag="ROH59_002696"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8196..8198),aa:Val,seq:gac)
     gene            complement(8237..8313)
                     /locus_tag="ROH59_002697"
     tRNA            complement(8237..8313)
                     /locus_tag="ROH59_002697"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8277..8279),aa:Val,seq:gac)
     gene            8621..9877
                     /locus_tag="ROH59_002698"
     CDS             8621..9877
                     /locus_tag="ROH59_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HDX4805157.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRH
                     PEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEACNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGAIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFGIGNINL
                     NGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            complement(9918..11291)
                     /gene="mdtK"
                     /locus_tag="ROH59_002699"
     CDS             complement(9918..11291)
                     /gene="mdtK"
                     /locus_tag="ROH59_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HDX4805158.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAI
                     ILQRAAR"
     gene            11506..12147
                     /gene="ribE"
                     /locus_tag="ROH59_002700"
     CDS             11506..12147
                     /gene="ribE"
                     /locus_tag="ROH59_002700"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDX4805159.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(12187..13335)
                     /gene="cfa"
                     /locus_tag="ROH59_002701"
     CDS             complement(12187..13335)
                     /gene="cfa"
                     /locus_tag="ROH59_002701"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HDX4805160.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(13626..14837)
                     /locus_tag="ROH59_002702"
     CDS             complement(13626..14837)
                     /locus_tag="ROH59_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HDX4805161.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKPVLFIGLTIFALGSLGMLWVENAATLLILRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNH
                     GNAEVAHSESH"
     gene            14950..15882
                     /locus_tag="ROH59_002703"
     CDS             14950..15882
                     /locus_tag="ROH59_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4805162.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     LVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALKLENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(15879..16904)
                     /gene="purR"
                     /locus_tag="ROH59_002704"
     CDS             complement(15879..16904)
                     /gene="purR"
                     /locus_tag="ROH59_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HDX4805163.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            17203..17292
                     /gene="ynhF"
                     /locus_tag="ROH59_002705"
     CDS             17203..17292
                     /gene="ynhF"
                     /locus_tag="ROH59_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein YnhF"
                     /protein_id="HDX4805164.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            17458..18627
                     /locus_tag="ROH59_002706"
     CDS             17458..18627
                     /locus_tag="ROH59_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4805165.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFLSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHVTPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAIVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPEAVCVANS"
     gene            complement(18773..19354)
                     /gene="sodB"
                     /locus_tag="ROH59_002707"
     CDS             complement(18773..19354)
                     /gene="sodB"
                     /locus_tag="ROH59_002707"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HDX4805166.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKPLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(19482..20309)
                     /gene="mepH"
                     /locus_tag="ROH59_002708"
     CDS             complement(19482..20309)
                     /gene="mepH"
                     /locus_tag="ROH59_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-endopeptidase MepH"
                     /protein_id="HDX4805167.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTQKTQKASQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNK
                     TASASFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPY
                     RWGGSSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFF
                     RTQGRGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            20644..20991
                     /gene="grxD"
                     /locus_tag="ROH59_002709"
     CDS             20644..20991
                     /gene="grxD"
                     /locus_tag="ROH59_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HDX4805168.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(21042..21134)
                     /locus_tag="ROH59_002710"
     CDS             complement(21042..21134)
                     /locus_tag="ROH59_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001441976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDX4805169.1"
                     /translation="MNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(21363..22010)
                     /gene="rnt"
                     /locus_tag="ROH59_002711"
     CDS             complement(21363..22010)
                     /gene="rnt"
                     /locus_tag="ROH59_002711"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HDX4805170.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAAEV"
     gene            complement(22113..22520)
                     /gene="gloA"
                     /locus_tag="ROH59_002712"
     CDS             complement(22113..22520)
                     /gene="gloA"
                     /locus_tag="ROH59_002712"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDX4805171.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTNVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(22601..23698)
                     /gene="nemA"
                     /locus_tag="ROH59_002713"
     CDS             complement(22601..23698)
                     /gene="nemA"
                     /locus_tag="ROH59_002713"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HDX4805172.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRISPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(23735..24334)
                     /gene="nemR"
                     /locus_tag="ROH59_002714"
     CDS             complement(23735..24334)
                     /gene="nemR"
                     /locus_tag="ROH59_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416166.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NemR"
                     /protein_id="HDX4805173.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV"
     gene            24437..24676
                     /locus_tag="ROH59_002715"
     CDS             24437..24676
                     /locus_tag="ROH59_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HDX4805174.1"
                     /translation="MTEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            24725..25621
                     /locus_tag="ROH59_002716"
     CDS             24725..25621
                     /locus_tag="ROH59_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HDX4805175.1"
                     /translation="MVQRITIAPQGPEFSHFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTACEENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            25702..26223
                     /gene="sodC"
                     /locus_tag="ROH59_002717"
     CDS             25702..26223
                     /gene="sodC"
                     /locus_tag="ROH59_002717"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HDX4805176.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEVKDKALIVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(26224..28236)
                     /locus_tag="ROH59_002718"
     CDS             complement(26224..28236)
                     /locus_tag="ROH59_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDX4805177.1"
                     /translation="MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWRPETTDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPDATREIL
                     EQLLTALASSQTDVYTVARIISPLRPTNVTDYRHIAFWQRLRYFCRLYLQSSQELHRL
                     QSGVDDHARLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(28236..29093)
                     /locus_tag="ROH59_002719"
     CDS             complement(28236..29093)
                     /locus_tag="ROH59_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416161.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX4805178.1"
                     /translation="MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQ
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LQGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFTLDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(29096..29332)
                     /locus_tag="ROH59_002720"
     CDS             complement(29096..29332)
                     /locus_tag="ROH59_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HDX4805179.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVIHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            29533..29967
                     /gene="slyA"
                     /locus_tag="ROH59_002721"
     CDS             29533..29967
                     /gene="slyA"
                     /locus_tag="ROH59_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HDX4805180.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG"
     gene            complement(30014..30481)
                     /gene="slyB"
                     /locus_tag="ROH59_002722"
     CDS             complement(30014..30481)
                     /gene="slyB"
                     /locus_tag="ROH59_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HDX4805181.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRQVQIQGGDDSNVIGAIGGAVLGGFLGNTIGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTHFSPGQRVVLASNGSQVTVSPR"
     gene            30755..31864
                     /gene="anmK"
                     /locus_tag="ROH59_002723"
     CDS             30755..31864
                     /gene="anmK"
                     /locus_tag="ROH59_002723"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDX4805182.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATVAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP"
     gene            31962..32291
                     /gene="mliC"
                     /locus_tag="ROH59_002724"
     CDS             31962..32291
                     /gene="mliC"
                     /locus_tag="ROH59_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HDX4805183.1"
                     /translation="MSMKKLLLICLPVLLTGCSAFNQLVERMQTDTLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGEEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            32350..33006
                     /gene="pdxH"
                     /locus_tag="ROH59_002725"
     CDS             32350..33006
                     /gene="pdxH"
                     /locus_tag="ROH59_002725"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HDX4805184.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACE
                     AKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            33135..34409
                     /gene="tyrS"
                     /locus_tag="ROH59_002726"
     CDS             33135..34409
                     /gene="tyrS"
                     /locus_tag="ROH59_002726"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDX4805185.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            34471..35331
                     /gene="pdxY"
                     /locus_tag="ROH59_002727"
     CDS             34471..35331
                     /gene="pdxY"
                     /locus_tag="ROH59_002727"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310372.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase PdxY"
                     /protein_id="HDX4805186.1"
                     /translation="MKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHT
                     QYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAA
                     NPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHPVNNV
                     EEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQP
                     VGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIAN
                     PEHYFSATKL"
     gene            complement(35375..35980)
                     /gene="gstA"
                     /locus_tag="ROH59_002728"
     CDS             complement(35375..35980)
                     /gene="gstA"
                     /locus_tag="ROH59_002728"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HDX4805187.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(36086..37588)
                     /gene="dtpA"
                     /locus_tag="ROH59_002729"
     CDS             complement(36086..37588)
                     /gene="dtpA"
                     /locus_tag="ROH59_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HDX4805188.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHTILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAVIAVLMLFTAPKLHRMTQDDAADKAAKAAVA"
BASE COUNT         9707 a         9119 c         9848 g         9282 t
ORIGIN      
        1 ttcaaatgat aataaatatc acttcactta taatttcttg ctttgtgatt ttaattgata
       61 acgatcaatg ttaagagccc agaataatca cattattttt tctcctaacc ataaaggatt
      121 agtttgttag cgttaaatct tttctcatac actatcgggt tagggaaaat atctggtgtt
      181 gaggacagcg tcagcagcgt attagttgag tgcttaatat caggctgttg aattgtcagc
      241 actgtgtttg cgaagaggat gcgaaataaa tgaacccggt tgatcgtcca ctattaaata
      301 ttggcttaac gcgattagaa ttcttgcgta tatcaggaaa aggccttgct ggtttaacaa
      361 ttgcccctgc tttactgtca cttttgggtt gcaaacagga agatattgat agcggcacag
      421 tagggttgat aaatacaccc aaaggggtgc tggtgaccca acgtgcgcga tgcacgggtt
      481 gccaccgctg tgaaatctct tgtaccaact tcaacgatgg ctcagtaggg acattcttct
      541 cccgtatcaa aatccatcgc aattatttct ttggcgacaa cggggttggc tctggcggtg
      601 gcctgtatgg cgatctcaac tataccgcgg atacctgccg tcaatgcaaa gagtcgcaat
      661 gcatgaacgt ctgcccgatt ggtgcgatta cctggcagca gaaagaaggc tgtattaccg
      721 tcgatcataa acgttgtatt ggctgtagcg cctgtactac ggcatgcccg tggatgatgg
      781 ccaccgtaaa taccgaaagt aaaaaatcct cgaaatgtgt gttatgcggt gaatgcgcaa
      841 acgcctgccc aacaggggcg ttaaaaatta tcgagtggaa agatattact gtgtgaatct
      901 tgcaaaggaa aaaatcatgg ctaacggttg gacaggtaat atattaagag tcaatctcac
      961 gacaggaaat attaccctcg aagattccag taaatttaaa agttttgtcg gtggcatggg
     1021 cttcggctac aaaattatgt atgacgaagt accgccaggc acgaaacctt tcgatgaagc
     1081 gaataaatta gtttttgcta ccggcccatt aactggatct ggtgccccct gtagttctcg
     1141 cgtaaatatc acctcacttt ctacttttac caaaggaaat ttagtcgtcg atgcccatat
     1201 ggggggcttt tttgcagcgc aaatgaaatt cgctggatac gacgtcatta ttatcgaagg
     1261 gaaagcgaaa tcaccggtat ggctgaagat taaagatgac aaagttagcc ttgaaaaagc
     1321 cgatttctta tggggaaaag ggacgcgcgc aacgacggaa gaaatttgtc gcttgaccag
     1381 tccggaaacc tgtgtggcgg ctattggtca ggctggagaa aaccttgttc ctctctctgg
     1441 catgttgaat agccgtaacc acagcggcgg tgcgggaact ggcgcaataa tgggttcgaa
     1501 aaacctgaaa gcgattgcgg ttgaagggac gaaaggggtc aacattgccg atcgtcagga
     1561 gatgaagcgt ctcaacgatt acatgatgac tgaacttatc ggtgcgaata acaaccatgt
     1621 cgtgccaagt acgccgcaat cgtgggcaga gtattcagat cccaagtcac gttggacagc
     1681 acgtaaaggg ctgttttggg gcgcggctga aggtggtccg attgaaacgg gggaaattcc
     1741 gccaggcaat cagaatacgg tcggctttcg tacctataaa tccgtttttg acttaggtcc
     1801 ggcggcagag aaatacacag taaaaatgag tggctgccac tcttgcccga tccgttgtat
     1861 gacccaaatg aatattcctc gggtgaaaga gtttggcgtg cccagcacag gtggtaacac
     1921 ttgtgtagca aactttgtcc ataccaccat cttcccgaac gggccgaaag attttgaaga
     1981 taaggacgat ggtcgtgtga ttggtaacct ggttggtctg aatttgttcg atgactacgg
     2041 cctatggtgt aactacgggc agttgcatcg cgactttact tattgttaca gcaaaggtgt
     2101 gttcaagcgt gttctgcctg ctgaagagta tgcggaaatt cgctgggatc aactggaagc
     2161 gggtgacgtt aactttatta aagattttta ctaccgtctg gcgcatcgcg tgggtgagtt
     2221 gagtcacctg gctgatggtt catatgccat cgcagaacgc tggaatttgg gtgaagagta
     2281 ctggggctac gcgaaaaata aactctggtc gccgtttggc tatccggttc accatgccaa
     2341 tgaagcgtca gcgcaagtcg gttccattgt taactgtatg ttcaaccgtg actgcatgac
     2401 gcatacccat atcaatttta ttggttccgg cttgccattg aaactgcagc gtgaagtggc
     2461 gaaagagctt tttggttctg aagatgctta cgatgaaacc aaaaactaca caccgatcaa
     2521 tgacgcaaaa attaaatatg ctaagtggtc gctgttgcgg gtctgtttgc ataacgccgt
     2581 caccctgtgc aactgggtct ggccaatgac cgtttcgccg ctgaaaagcc gtaattaccg
     2641 gggtgatctg gcgcttgaag ccaaattctt caaagcgatc actggcgaag atatgactca
     2701 ggaaaaatta gatttagctg cagagcgtat ctttacgttg catcgcgcct acacggtaaa
     2761 actgatgcaa accaaagata tgcgtaatga acacgatctt atctgttcct gggtattcga
     2821 caaggatccg cagatcccgg tctttactga aggtacagac aaaatggacc gtgacgatat
     2881 gcatgcttcg ctcacgatgt tctacaaaga aatgggctgg gacccacagc ttggttgtcc
     2941 gacccgcgaa acattgcagc gtctggggct ggaagatatt gccgccgatc tggcagcaca
     3001 caatctactg cctgcgtaag gaatgggaga gatgaaccat caggatgaat tgccgttagc
     3061 gaaagtcagc gaaattgatg aggcgaagcg gcaatggttg caggggatgc gtcaccccgt
     3121 tgatacggta accgaaccag aaccggctga aatcctggca gagttcattc gccagcattc
     3181 tgcggctggg cagctggtgg cgcgcgccgt gtttctctcg ccaccctatt cggttgcaga
     3241 agaggaactg tcagttttgc tggaaaacat taagcagaac ggagactacg cggatatcgc
     3301 ttgtatgacg ggaagccagg atgattacta ttactcaacg caggccatga gtgaaaacta
     3361 cgcggcgatg tctttgcaag ttgtggagca ggacatttgt cgcgccattg cacacgccgt
     3421 tcgttttgag tgccagacgt atcctcgtcc ttacaaagtc gccatgctga tgcaagcgcc
     3481 atattacttc caggaagcgc agattgaagc cgcgatcgcc gcgatggatg ttgcacctga
     3541 atatgccgat atacggcagg tggagtcatc gacggcagtg ttgtacttgt ttagcgagcg
     3601 atttatgacc tatggcaagg cgtatggctt atgcgaatgg ttcgaggtag agcagtttca
     3661 gaacccctga aatttcaggg ggatgtcatg gatagggtgg acagttgcag ccactgcatt
     3721 aggggataat cagatgtcct tcactcgacg caaatttgtt ctggggatgg gaacagtaat
     3781 cttttttact ggttctgcgt cttctctgtt agcgaatacg aggcaagaaa aggaagttcg
     3841 gtatgccatg attcatgacg agtcacggtg caatggctgt aatatctgcg cccgcgcatg
     3901 ccgtaaaact aaccacgtcc ccgctcaggg aagccgttta tcgatagcac acattccagt
     3961 catcgataac gacaatggaa cgcagtatca cttttttcgt cagtcatgtc agcactgcga
     4021 agatgctcct tgcatcgacg tttgcccgac aggggcgtcg tggcgtgatg agcaggggat
     4081 cgtgcgggta gaaaaatcgc agtgcatcgg ctgcagttat tgcattggcg tttgcccgta
     4141 ccaggttcgc taccttaacc ctgtcactaa agtggcagat aaatgtgatt tctgcgctga
     4201 gacccgactg gcaaaaggct ttccgcccat ttgcgtcagt gcctgcccgg aacacgcatt
     4261 gatctttggt cacgaagata gcccagaaat tcaggcgtgg ttgcaggaaa ataaatacta
     4321 tcaatatcag ctacctggcg ccgggaaacc gcatctgtat cgccggttcg gtcaacattt
     4381 gattaaaaag gaaaatgtat gaacccgtcg caacatgctg aacagtttca gagccagttg
     4441 gcgaactatg tgccacagtt caccccccaa ttttggccgg tgtggttgat cattgccgga
     4501 ctattgctgg ttgggatgtg gttggtgctg gggctacatg ccttgcttcg tgctcgtggc
     4561 gtgaagaaat cagccaccga tcatagtgag aggatttatc tttacagcaa agcggtcaga
     4621 ttatggcact ggtcgaatgc gttactcttt gtattgttgc tggcaagtgg gctgataaat
     4681 cactttgcgc tggtgggcgc aactgcggtt aaaagtctgg ttgcggtgca tgaagtttgc
     4741 ggatttttgt tactggcatg ctggcttggc tttgttctga tcaatgccgt tgggggtaat
     4801 ggtcaccact atcgcattcg tcgtcagggt tggctggatc gagcggcaaa acaaacgcga
     4861 ttttatttgt ttggcattat gcagggggaa gaacatcctt tcccggcaac aacccagtct
     4921 aaatttaatc ccttacagca ggtcgcctat gttggtgtca tgtatggatt gttgccattg
     4981 ttactattga cggggctgct gtgtctctat ccgcaagccg tgggagatgt gtttcctggc
     5041 gtaagatact ggttattgca ggcgcatttt gctctggcat ttataagcct cttttttatc
     5101 ttcggtcatc tttatctttg caccacgggg cgtacgccac acgaaacctt taaaagcatg
     5161 gtcgatggct atcaccggca ctaacgaatg atcattacac gagcagacct gcgagaatgg
     5221 cgtatcggag cggtgatgta tcgctggttt ctgcgccatt tcccacgtgg cggtagttat
     5281 gccgatattc atcatgcact gattgaggaa ggatatacgg actgggcgga gagtctggtt
     5341 gagtatgcgt ggaaaaaatg gctggcagat gaaaacttcg cgcatcagga agtttcctct
     5401 atgcaaaaac tggccacaga tcccggagaa cgactatttt gcagtcagtt tgtccgcagc
     5461 gacgatcatg ctcgcctcgg ctgttgtgag gataacgcca gaatcgcaac cgctgggtat
     5521 gccgcgcaaa ttgccagtat gggttatagc gtgcggattg gaagtgtcgg ctttaacagt
     5581 cacattggca gctccggtgc acgcgcacgg gttgctgtaa ccggtaattc ttcgcggata
     5641 agcagcgctg gagatagcgg tcggattgcg aataccggaa tgcgagtacg cgtttgtaca
     5701 ttgggtgaac ggtgtcatgt cgccagtaat ggtgacctgg tgcaaatcgc cagctttggc
     5761 gcaaacgcca gaattgccaa cagcggcgac aatgtacaca tcattgccag tggtgaaaat
     5821 tcaacggtag tgagcacggg cgtggtcgac tcaattattc tcgggccagg gggatgcgcc
     5881 gcactggcat atcatgacgg cgaaagagtt cgcttcgccg tcgccattga aggtgaaaac
     5941 aatattcgag ccggagtccg ctatcgtctt aatgaacaac atcagtttgt tgagtgctga
     6001 tagctttacc tttaatcaaa cgaaagacgc cgacgcgcac gggatgcagg ttttacgacc
     6061 gcccgagcca tcgcctctcc aatttctgca catgccgtaa ttccctgaac gaaaggctgg
     6121 tcgtgcatca accagggcaa cgcgccgaac gctacgcgcc cacgaatatc ttcgggttgc
     6181 tgtaacgtat aatcttcgcc aacattaggg atttcatccc ctgttttctg taattgttcg
     6241 cgtagtccag ggaaaggaat atctttcact ttaagcggac gctgcccgcg ggcatcaata
     6301 aaaacgtcaa acgagtagct attgtcttcc gttttcagga cggtgcgcga ctcattaatt
     6361 tccatttcgt agtcttcacc gagggcgaga atatgaatga ttcccgcttc acgtaaggcc
     6421 agtagtcgac gaatagactc tgaagggatt gccgcataat tatcgatgaa aacccgggca
     6481 aggcctttac tgaaccgttt atggtcgtgt tcattcagat gtggaacaat ttcctgtacg
     6541 gcttcatgca ggcgcagaat gacataacgc cagggaacag tatgtttttc tcgtttattg
     6601 cgttcgactt cctggagatt ttcttctgcc cagtcaaatg ggtcgcgttg tttgcgctcg
     6661 gcaaaccagg cttgagcaaa ggaatcgaca ttcaggctct ctaaggctat gcgttggctc
     6721 cagtctggat cagcaaactt gatttcctct actatcaatc taaatacccg atccaaaagg
     6781 cccacttcgc ctttttgaat ctcagcattt aatgcctgat cggtgatgat gtgtaagggc
     6841 tcgtagggaa tagggcaata gaaatcggct tcgggtaaaa tacctgtgcg cgacattaac
     6901 gtaatattta gcttttcatt tgcgttatcg cggtgaaaag tgacgtgttg tttatcatct
     6961 tcaatgaacg aaccatgctg aatagccact gccattgccg catccagtcc gctcaaggat
     7021 gttcccataa tacccacgtt acacgcatcg acctttgctt ccatcaggcc tgaccacggg
     7081 ctgggaaaat acgttctggt tgcttcttct tcatcaggcc agacgtgccc cgttgcgatc
     7141 accgctaaat caaacgtctc gctgggtaaa ttcagatttg tagcgagcat gacgccagca
     7201 tttgtaattt gcagatcggt aacctggcat gattcataaa cagccactgc aaatttttgc
     7261 tgtcgtgcct ggtctactaa tcgtaaaaat tgatcgcgga aatattcgcc cagcagaatt
     7321 cgcggtaaaa actgacgatc gtgcaaggtt tcttttttaa cgccataacg ctggagatgg
     7381 ctggcttctt gcttttgtag ccattcgaga tacgtgcaat aaatcggcgg tatttcaata
     7441 ctggcaatgt ttgccagcat cagttttgag ttttcctcat cactgtatgg catcccgata
     7501 ccggcttcgt cagcctgatc gaagatagaa atagaaagtg gcgtttgttg ctgtagaagc
     7561 gagaataagg tgtagatccc cgtaggcccg gcacccacaa tagcaattgt tttcattgtt
     7621 acttacctgt acgcattctt tcgaatttag tgttatcagg taagtttggt tgagattttt
     7681 agaatttgag aaatttcaga cagggatgaa aagggcacta accgcccttg attaaaatct
     7741 gtcaggcaag ttttgcctga ttgatttgac tcagtggcac attgacatcg aaaactttgg
     7801 cgacaacttc ctcaacgccg agatttttca gtcgggcagt atgtttttcc agataggcaa
     7861 gggcgctttt ttcatcagtg aaaaggtaga tcccaccggc ttcgtggttc ttttcacttt
     7921 ctgtccaaac cttccacaga aaaccaggtt cctgattaat cgactcagca agcggtttaa
     7981 gctgctcagc cattgtgtcg ccaaatgggc cattgaaaga aaaatgaagt tgtaacaaag
     8041 ttgccatagc gattctcctt ctgataacgc atacgaagac agtgtaaatc ttttaacgta
     8101 ttggatacag agaagaaaca gagggaaaaa aggagaagac cagattaaga aaatctggtg
     8161 cgtccgagtg gactcgaacc accgaccccc accatgtcaa ggtggtgctc taaccaactg
     8221 agctacggac gcaggatggt gcgttcaatt ggactcgaac caacgacccc caccatgtca
     8281 aggtggtgct ctaaccaact gagctatgaa cgcaacgttg taggtgacaa cggggacgaa
     8341 tattagcggc agagtgggaa ggtggcaaga ggcaaaacgt aattttctgc gctatttcga
     8401 ccgtttgcag agcttttaag caaattggct atattttgtt gatttgcaag ggcgattttt
     8461 attcaggatc gcatttacat ctgatacaac ccaataatcc gtgtatcaga gtttaaacag
     8521 agttgtttgc caccatctca aatctgtcgt ggataaatcc ttcgtagcct ttacacttag
     8581 gtagcaataa aggcacacag atgcagcaaa ggaataaatc atgggatctg atgcgaaaaa
     8641 cttgatgagc gacgggaacg tgcaaattgt taagaccggc gaggttattg gcgcgacgca
     8701 acttactgaa ggcgagttga ttgttgaagc tggcggaaga gccgaaaata ccgtggtcac
     8761 gggggctggc tggttgaaag tggcaaccgg tgggatagcc aaatgcacac agtacggtaa
     8821 caatggcaca ctatcggtca gcgacggtgc cattgccaca gatattgttc agtccgaggg
     8881 aggcgcaatt agtctctcta cgctcgctac ggttaatggc cgccatcccg aaggtgaatt
     8941 cagcgttgat aaaggttatg cctgcggttt gttgctggaa aatggcggta acctgcgtgt
     9001 actggaaggc catcgcgcgg aaaaaattat tctcgatcaa gagggtggcc tgttggtcaa
     9061 tgggacaacc tcagcggtcg tggtagatga aggtggtgaa ttgttggtgt atccaggtgg
     9121 ggaagcctgc aattgtgaga ttaatcaggg cggcgttttt atgctggcgg ggaaagccag
     9181 tgatacgttg cttgctggtg gcaccatgaa taatctcggt ggtgaagact ctgacactat
     9241 tgttgagaat ggagccatct atcgtctggg gacggatggt cttcagctct acagttccgg
     9301 taagacgcaa aacctgtccg ttaatgtggg tggtcgggct gaagtgcatg ccggtacgct
     9361 ggaaaatgcg gtaatacaag gtgggacagt gatcctgttg tcacccacca gcgcggacga
     9421 aaattttgtc gtagaggaag atcgcgcacc ggttgaactg accggtagtg ttgcattact
     9481 ggacggcgct tcaatgatta ttggctatgg cgcagatctg caacaatcaa cgattactgt
     9541 acagcagggc ggtgtattga ttctcgacgg cagtacggta aaaggtgaca gtgtcacttt
     9601 tggtattggt aacatcaatc taaatggcgg aaaactgtgg ctgatcactg atgcggcaac
     9661 gcatgtgcaa ctgaaagtga aacgcctgcg cggagaggga gccatttgcc tgcaaaccag
     9721 tgcgaaagaa atttcacctg acttcatcaa tgtgaaaggg gaagttactg gtgatataca
     9781 cgttgagata acagatgcca gtcggcaaac tctgtgtaac gcactgaaac tacagccaga
     9841 cgaagacggg attggcgcaa cgctccagcc tgcgtaaaaa cacaggcgca acccgtgaag
     9901 gttgcgcctt gtctttacta gcgagctgct cgttgcagaa tgatggctga cggcagacgt
     9961 tgcaggaacc gcatacgcag catcatcata atggctgccg aagtcaggcc aataataaag
    10021 cctatccaga agcctgctgg ccccataggt tcaacgacca gatcggtcag tgccagaata
    10081 tagccgcttg gcaagcccag cacccagtaa gccgtaaagg tgatatagaa aatggaacgt
    10141 gtatctttat aaccacgcaa aatcccactg ccaatcacct ggatagagtc agaaatctga
    10201 tataccgccg ccagcagcat caaatgcgca gccagcgtta caacctcggg attgtcgttg
    10261 tacaacaggg cgatttgctc tcgcagtgaa accgtgaata tggccgtcag ggttgccata
    10321 cagacaccca ccataagccc ggtccgcgca gcggtttgcg catccagcgt tgagccttga
    10381 cccagacgat aacctacgcg gatggttacc gctgccgcca gcgacatggg aagcacgaac
    10441 atcagtgaac taaagttcag ggcaatctga tgtcctgcga catcaacaat accgagcgga
    10501 gacactaaca gagccacgac ggcaaacagc gttacttcaa agaacagtgc cagcgcaatt
    10561 ggcaaaccga gttgaatcag tcgtttcata accgcaggat cgggcttcgc ggtgcctttt
    10621 tcgttacgaa tatcgcgcat cgagcgggcg cgtttaatgt aagaaaccat ggcaaggaac
    10681 atgacccaat acaccgccgc agtagccacg ccacaaccaa cgccaccgag ctcaggcata
    10741 ccgaaatgac cataaataaa gatatagttc accggaatgt tcaccagcag gccgataaag
    10801 cccatcacca tacccggctt ggtttttgcc agaccttcac actggttacg ggcaacctgg
    10861 aagaaaagat agcccggcgc gccccatagc aacgcacgca gataacccac ggctttgtcc
    10921 gccagagccg gatcgatgtt ttccatggag cggataatgt aacccgcatt ccacagtacc
    10981 agcataatga gaacggaaac aaaacctgcc agccagaaac cttgtcgcac ctgatgcgca
    11041 atgcgctcac gtcgaccgga accatttaat tgcgcgataa ccggcgttaa tgccagcagc
    11101 agtccgtgac caaagaggat cgccggaagc cagatagaag ttccgatagc aaccgccgcc
    11161 atgtcggtgg cactatagcc gcccgccatc acggtatcga caaaacccat cgcagtttgg
    11221 gcgatttgcg cgagaatcac cgggattgct aatgctaata acagacgcgc ttcactgata
    11281 tacttctgca cgtgaacacc ttttatttgt agttatatga gagactaaaa agccgcctga
    11341 atgggcagca aaaagaagaa gcaggggaaa ttcagtctat tgtagcgagg atttattaat
    11401 tctccagtga aaaaatagcc attcttaccc cttcactggt aagggcgttt tccacctgct
    11461 attgtgctga acagaatgtc ttaactgatt tcaggagttg taagtatgtt tacggggatt
    11521 gtacagggca ccgcaaaact ggtgtcgatt gatgagaaac caaattttcg cacgcatgtg
    11581 gtggagttac ccgaccacat gctggacgga ctggaaaccg gtgcgtccgt ggcgcataac
    11641 ggttgctgcc tgaccgtgac ggaaattaac ggcaaccatg tcagttttga cctgatgaaa
    11701 gaaacgttac gcattactaa tcttggtgat ttaaaagtgg gggattgggt aaacgttgag
    11761 cgtgcggcga aattcagcga tgaaattggc ggacacttaa tgtcaggtca tattatgacc
    11821 accgctgaag tggcgaaaat attaacctcg gaaaataatc gtcagatctg gtttaaagtc
    11881 caggatagtc agttgatgaa atatatcctg tacaaaggat ttattggcat cgacggtatt
    11941 agcctgaccg tcggcgaagt cacgccaacg cgtttttgcg tccatttaat tccggaaaca
    12001 ctggaacgca cgactcttgg gaagaaaaaa ctcggcgcac gcgtcaacat tgaaatcgat
    12061 ccacaaactc aggcagtggt agatacggta gaacgtgtgc tggcggcacg agaaaatgcc
    12121 atgaatcaac caggtacaga agcctgatct gaaatcgccc ccggagcggg ggcgatagaa
    12181 tagcctttag cgagcgactc gaaggccgtt ttcaacaccg cgtgagaaca cgacctgcca
    12241 gagctgaata tcacgggcgc ggaaagcacc tgcacaggca ttcagataat aggtaaacat
    12301 ccgtttaaag cgttcactgt agttatccgc aatttctggc catgcggcga ggaatcgttc
    12361 ataccacgcc atcaacgtag tatcgtaatc agcaccgaag ttatgccagt cttccatcac
    12421 aaagtggggt tcgctggact gagctatctg gcgtacagag ggcaggcaac cgttcggaaa
    12481 aatatattta ttaatccagg gatcaacatt cagatcggtt tttttcgaac cgatggtatg
    12541 gagcaggaat ataccttccg gtttcaaatt acgatccacc accgcaaaat aggtatcgta
    12601 atttttcggt ccgacgtgtt cgaacatccc cacagaaaca atacgatcaa actggtcgtt
    12661 caggtcacga taatcttgca gcaaaatggt gacatccagg ccttcacagc gttcctgagc
    12721 cattttttgc tgttcggcag aaatggtgac gccgaccacg cttacgtcat aattagacgc
    12781 catgtagtgc gccagtccgc cccagccaca gccaatatcc agtacgcgca tccctggttt
    12841 taactgcaat ttttcacaaa tcattttgag cttcgcctgc tgggcagatt ccagattatc
    12901 ggcatctttc cagtaagcac aggaatattg catgaagggg tcaagcatgc ggctgaacaa
    12961 gtcattaccc aaatcgtaat gctctttgcc gactatccag gcacgttttt tactctgcag
    13021 attgaagaga cgagcgccgg caatacgcag cgtgtctttg aaatgatggg gaagttggtt
    13081 ctcgagacct gcgcgtaaga ctttgctaaa aaacatatcc agtcggtcac attcccacca
    13141 gccatccata taactttcgc ctaaccccaa cgatccttcc tgcagaacgc gtttaaaaaa
    13201 atcggggttt ttgacacgaa tatccgccgg ggcagaaccg ttaatggcta taccggcacg
    13261 gctaagtaat tcgttggcga tacggtacca gttgtcatct ggtacactga cttcttctat
    13321 acacgatgaa ctcatagttt ctccatcact ggtcggtgat cagaacctta aaacagcgta
    13381 gacgcttttt gggctttgtg agaaatctcg cagaaaaaac cgcgagtcta taatccgacg
    13441 tagaacagag ggaaaggagg aacccttgcc gaaatgacca tccatagtga gtcgggaacg
    13501 atcctgtccc cgtaataaca taatatttat cgtagtttta acaactcgaa attagtatag
    13561 gccgctaatt tcaatcatac aacaaaattt tgttagcagc ctaagtataa gtatatcgat
    13621 atagatcagt gtgattcact atgagcgact tcggcattgc catgattctg gcagccaact
    13681 tcttcacaac gttgcatcat gtaacccaga gcgaccagca ctactgttga taacatcacg
    13741 ctggtggtgg tgagcaatgg cgtactgata ctgataagcc aggaaactac cagacttgcg
    13801 aggaagcaca gacccagttg cagagtgttc tgcaacgctg cggcgcgacc ggttgcatgt
    13861 gggaagggac gcagcgcctg ggcaacaaca atcgggtaga tcgcgccgtt ggcaatcgcc
    13921 atcacacaga atgggatcag gatttcgacc aacgacacat ggctaatgaa gcccgcagcc
    13981 caggtcgcaa tgacgctgac agcaaacagt accagcaacc acggtaataa ctgcttgcct
    14041 tgccatttct gcagcgcggc gcgacagcca taaccaccaa tcagaaacgc gatagtttgc
    14101 gggacataac ttaaaccaat aactgccggg ctgtaaccca tttcactaag gatgaacggt
    14161 gaaccggtca gccatgcaaa aaaactggct gaacaggctg cgtatatcag cacgttgccg
    14221 cgataggttt tagaacgtag caggtcggta aaggtcagac catcctgact attgttacgg
    14281 gccttcgtcg tgggtttgag ccagaaaata ggcagaatca gcaccacggt aatggcaaac
    14341 agggtggcga aaatcgcctg ccaggaaaaa tggaccagca gccagcttcc taacagagga
    14401 gccagtgccg gagatagacc caccagcggc atgatggtcg caaaaatacg gttaactttc
    14461 tgtgaaggat aataatctgt cactaatgct tgccagataa ccgccgcggc gcagacaccc
    14521 acagcctgta caaaacgcaa tatcagcagc gtggcggcgt tttccaccca cagcatcccc
    14581 agactaccta acgcaaaaat tgtcaggccg atgaataaca ccggtttgcg accataacgg
    14641 tcggagagtg gcccccacag aagctgggct gcggcaaaac cggcaaggaa cagactaagg
    14701 ctggcactga cagcagacgc aggcgtttgc aggtcggcct gtatggcggc gaaagcaggc
    14761 agatacatat cggttgccag aaaaccgagt acgctcaaac ccgccagcca gactaaaaat
    14821 cttttcccag gttgcatgta tattctctaa atctctcaat taaacaccgc cgcaaagtgt
    14881 agggagtgaa attagtgttg tgaaacggta atatttgatg attggtttca aaaattttgc
    14941 aggcagacta tgtggtcaga atattctctc gaagttgttg atgcggtagc gcgtaatggt
    15001 agttttagcg ccgcagccca ggagttgcat cgcgttcctt ctgcggtcag ctataccgtg
    15061 cgtcagctgg aagagtggct ggcggtgccg ctgtttgaac gacgtcaccg tgatgtggaa
    15121 ctgaccgcag ccggggcgtg gtttctcaaa gaagggcgct ctgttgtcaa aaaaatgcag
    15181 atcacccgcc agcaatgtca gcagatagcg aacggctggc gcggtcagtt agctatcgca
    15241 gtggataata ttgtcaggcc agagagaaca cggcagatga tcgttgattt ttatcgccat
    15301 tttgatgatg tcgaactcct tgtctttcag gaagtgttca acggtgtctg ggatgcactt
    15361 tccgacgggc gcgtggaact ggcgattggc gcaacacgcg cgattccggt aggcggtcgt
    15421 tatgccttcc gggatatggg gatgttaagc tggagttgcg ttgttgccag ccaccacccg
    15481 ctggcgttga tggatggccc gttcagcgat gatacgttgc gcaactggcc gtcattggtg
    15541 cgcgaagaca cctcgcgaac gctacctaaa cgtattacct ggttgctgga taaccaaaaa
    15601 agacttgtcg tgcctgactg ggaatcatcg gcaacctgta tctcggcagg attatgcata
    15661 gggatggtgc caacacattt cgccaaaccg tggcttaatg aggggaagtg ggtagcacta
    15721 aaactggaaa accccttccc ggattcggca tgttgtctga catggcagca aaatgatatg
    15781 tcgcctgcgt taacctggtt gcttgagtat ctcggcgata gtgagacgct gaataaggag
    15841 tggctgcggg agccggaaga gactcccgca acgggtgatt aacgacgata gtcgcggaac
    15901 gggccgtcag ccacggagcg gcgttcaatc aaccgcggat gcacttcaat ggactgcggt
    15961 tcttcacgtt tgttgacgat acgatccaac agcatgttga acgctgtttc gcccagcgaa
    16021 tcttttggct gatggatcgt ggtcagcgcc ggcgtaaaat agcgggcgtt gcgcacgtta
    16081 tcataaccga tcagcgaaac atcctgcggc acgcgcagac ccatttcatc agcagcacaa
    16141 agtgcgccca ttgccatgat atcgccacca cagaagacgg cagtagggcg atgcgactgc
    16201 gacaggattt gctgcatggc gcgataaccg gattcaggtt caaagtcacc ctgcacaatc
    16261 cagctttccg gcactttgat catcgcttct tccatcgcct tcataaaacc agcaagacgg
    16321 cctgcgccgg tgttacgttc cagcgggcca gggataacgc cgatttcgcg atgaccgcgt
    16381 tcaatcagat aacgcccggc catgtagccg ccttcgaacg cgttatcaat gaccgcatcg
    16441 gtgaagtcag cttttgcttc accccagtcc atcaccacca ttgggatatg gcgatactct
    16501 tccagcatcg ccagcaacgg ctctgggtac tcagaacaca tcaccagcag accatcgacg
    16561 cgtttttgcg ccatcatcga cagataagcc cgctgtttct caagattgtt ccacgcattg
    16621 cccagaatca gggtgtaacc tttctggaag caattttttt cgaccgcttc aatgatctcg
    16681 gcaaaatagg ccgcttcgct gctggtcgcc agcaaaccga tagacttggt gtggttaacc
    16741 ttcaggctac gcgccaccgc gctaggggag tagtgtaatt ctttgattgc tgcccacacg
    16801 gcattgcgcg tttcttcagc gacgaaacgt gttttgttga tcacgtgtga cacagttgta
    16861 gtggaaacgt ttgctcgttt cgctacatct tttattgttg ccattccatt tcactccaga
    16921 ccctaacttc agctcctgca aattcgcaag gtaaacgttt gcctttacac accttacgca
    16981 caacaaaaat gttgcggtac gccggaaaaa cgacacggag cgtcaggaag gggtcaatgg
    17041 ccagtacgca aatagtgtaa gcgtggaatt ttggccgatc ttgacgaaaa ggggaagtag
    17101 taaaaacact tatcattata aatgacggga gattttttca tcacagtgtg taaaaatgcg
    17161 taatatcact ttttgtgtgg taataaaaaa ggagaaaact tgatgagcac cgaccttaaa
    17221 ttttcactgg taacaacgat tatcgtcctc ggtttgatcg tggccgtggg tttgactgcc
    17281 gcgctgcact gatttcctct cgagggagcg cgttctccct cgcatctcct tcctgtttgt
    17341 tagcaaaatg gcaaaagtgt tttctctttt tgttattttc atttttttgt gattactgtc
    17401 atgctttcgc cactttaatg aatatcgcgt aatgacgcga agaggtggag ataaggcatg
    17461 aaaattaact atccgttgct ggcgctggcg attggcgcgt ttggtatcgg gacaacggag
    17521 ttctcgccaa tgggcttgtt gcccgtcatt gcgcgcggtg tggatgtctc gattcccgct
    17581 gccggaatgt taatcagtgc ttatgcagtt ggcgtaatgg ttggcgcgcc gctgatgacg
    17641 cttctacttt ctcatcgtgc ccgccgcagt gcgttgattt tcctgatggc gattttcacg
    17701 cttggcaacg tactttccgc catcgcgccg gattatatga ccctgatgct ttcacgcatt
    17761 ttgaccagcc tgaatcacgg ggcatttttt ggtttgggtt cagtcgtggc cgcaagcgta
    17821 gtgccaaaac ataaacaggc cagcgcagtt gccactatgt ttatggggtt aaccctggca
    17881 aatatcggtg gcgtgccggc ggcgacctgg ttgggcgaaa ccatcggctg gcggatgtca
    17941 tttctggcaa cagcggggct gggcgtgatt tcaatggtaa gtctgttcct ctcattacct
    18001 aaaggtggcg caggggcgcg acctgaagtg aaaaaagagc tggcggtatt aatgcgtccg
    18061 caggtgctgt ctgcattgct gacgacggta ctgggcgctg gtgcaatgtt taccctctac
    18121 acctatatct ctccggtact gcaaagcatt acccacgtaa cgccggtgtt cgtcacggca
    18181 atgctggtgc tgattggtgt cggattctct atcggtaact atctcggcgg caaactggca
    18241 gatcgttcag ttaacggcac gttgaaaggc tttttgttgt tgctgatggt gattatgctg
    18301 gcaatcccgt tcctggcccg caatgagttc ggcgcagcta ttagcatggt ggtgtgggga
    18361 gctgcaacct ttgcgatcgt accgccgtta cagatgcgcg tgatgcgtgt cgccagtgaa
    18421 gcgccaggtc tgtcttcatc agtcaatatt ggtgccttta atcttggaaa tgcgctggga
    18481 gcagctgctg gtggtgcggt aatttccgct gggctgggat acagttttgt gccggtgatg
    18541 ggggcgattg tcgcgggact ggcattattg ctggtgttta tgtcagccag aaaacaacct
    18601 gaagcagttt gcgttgccaa cagctaatta aacaaaaacg cagaaggata accttctgcg
    18661 ttacagttgc tggcaacgtg cgatttatct tgccgaatgc gctgttaacg cctcatccgc
    18721 gttggcatgg taagcgaagc gcatcaggta atgttgcatt tgccatcagt tattatgcag
    18781 cgagattttt cgctacgaat tcccagttca ccagcgccca gaagtgctcc agatagccag
    18841 ggcgtgcatt gcgatagtcg atgtaataag cgtgttccca gacatcaacg gtcagcagcg
    18901 gagtcgcatc ggtggtcagt ggagtacccg cgttagaggt tgaaacgata gccagtttgc
    18961 catcgctgtt tttcaccagc caggtccagc cagaaccaaa gtttttgatc gctgcatcag
    19021 taaactgagc tttgaaatcg gcaaagctgc caaaagatgc ggcgatagct tcagcgactt
    19081 ttccagtcgg ttcgccaccc gcgttcggtg ccaggcagtt ccagtagaaa gtatggttcc
    19141 agacctgagc tgcgttgttg aatacgccac cttcagagct gcgaataatc tcttccagtg
    19201 gtttaccttc aaacgcggta cctttgatca ggttgttcag gttagtgaca taagtctgat
    19261 gatgtttgcc gtagtgatac tcgatggttt ccgcagaaat gtgcggtgcc agagcatctt
    19321 tagcatatgg tagtgcaggt aattcgaatg acattgctac tctcctttat tattaatttg
    19381 catacgtaca atagccttat tgtgcgtatg gatagggtag caaattaaaa ggtgagacaa
    19441 aagatgaact taccctgttg ccgtaacaac agggtaaagt tttagcgaag tgtttttggg
    19501 gtcattaccc ggcgagcgcc aacatagtgg cgctgccagt agtcttcact gagagaagtg
    19561 atttgaattt cctggcccgt gcgcggtgac tgaataaatt tgccgttgcc gacatacacg
    19621 ccgacatgat cggctgtacc gcgtccctga gtacggaaga agaccaggtc gccgtttttc
    19681 agttcactac gttcgattgg cgctgcatcg cgcaggtgat acatttcatt cgccgtacgc
    19741 ggaatacgaa ttttcaccaa atctttataa gcgtaataaa ccagaccgct gcaatcaaaa
    19801 ccggtacgcg gtgagctgcc accccaacga tatggcttac caatttgctg catcagttta
    19861 ttcattgcca cttttgtggc tttttgcacc ttcgctttgt gcgcgtcggc aagggttcct
    19921 gacgcggcat ttttgacttt cacacaatgc gatttatagc ccttacgttt ggtacacttt
    19981 tcggtaaagc tggctgaggc cgttttattg acggcgtgtt tgctgcgagt tttggcgttt
    20041 ttagaagcgg taatggaaga ttttttaacg gaagaagcgg ttttgctttt ggtcgtactt
    20101 ttactggcgg cttttttcgc tgttttctgg ctggctttct gggtcttttg ggtggttgcc
    20161 gtgcttttct ttttatctgc ttttttggtg atatgagtgg tagcagaact ctccctggct
    20221 tgctttgaag catgggccat aggcgttaaa ggcagggtgg taaaaagtaa agcacagagc
    20281 gtgatcgaaa tacggtttat ccgcgccact gagcgtccct ctgttaaggc aggtctatca
    20341 tgcctgcgtc tgatttacaa aacttgatga ttctaatgca tagaagaaga gaaagttaat
    20401 agcttttatt gttaaaaaat acgtttcgtc ggcgagcgca aaaaaatgca gcagtgaaag
    20461 ctaaaaatgg ttataaatac gccagtttgc cgtgcatcag ggaagaaacg aatatttgaa
    20521 atgcaacaaa tagagcaaag ggataaaata gcaaaagcgt gatgaaaatg ttattttccg
    20581 atgccgcact gacccgctac aatgtcagat tactgccgta aagaagtttg aggaagcaag
    20641 acaatgagca ccactatcga aaaaatccaa cgccagattg ctgaaaaccc gatcctgctg
    20701 tacatgaaag gttcaccgaa actgccgagc tgcggtttct ctgcccaggc agtccaggcg
    20761 cttgccgcat gtggcgaacg ttttgcctat gttgatattc tgcagaatcc ggacattcgt
    20821 gcggaactgc cgaaatatgc gaactggccg accttcccgc aactgtgggt tgacggcgag
    20881 ctggtgggcg gttgtgatat cgtgatcgaa atgtatcagc gtggtgaact gcagcagctg
    20941 atcaaagaaa ctgccgctaa atacaagtct gaagagccgg acgcggaata atccgtcctg
    21001 caatactgac ggatgcgaac gggcatccgt cagtcctttc tctatcccca atccagccct
    21061 tgtggcgaac ttgaaaatcc cgcctcacgt aacagcgtaa acatcggcgt ttgccggacc
    21121 ggtaggtcat tcacttctgt tagcgtaaag cgcagccgtg gttcgcgact agacagcggt
    21181 cggctgttta aaggcgcgaa gaaaccagtc gcgggtcgcc ggcgaaaaca cgtccggcag
    21241 gggcgatgaa gggtttggat tatttgccat taacgctatt ccccgtgaat atcatgcatg
    21301 atgcgtggaa tagcctcact atagatgcct gaatcattgc atgtcatcag gcatcgactc
    21361 gattacacct ctgcggcggc aggtagtggc cagcctccca gacgtttcca gcggttgacg
    21421 atttcacaaa acagcacagc agtgcgttcg gtgtcgtaca gcgcggagtg cgcctgggtg
    21481 ctgtcgaagt ccatgccagc tgtctggcaa gcctttgaca atacggtttg tccgagtgcc
    21541 agcccggcca gtgcagcagt gtcaaaagtg gcgaaagggt ggaacgggtt acgtttcagt
    21601 gaggcgcgtt ctgcggcggc catcataaag ctgtgatcga aattggcgtt gtgcgccacc
    21661 ataatggcgc ggttacagcc gctcgcttta atacctttac gtacaacttt aaaaatttcg
    21721 tgcagcgcct cgtactcgct gaccgcgccg cgatcgggat cgttcggatc aatgccattg
    21781 aaggcaaggg cctctggttg caaatttgcg ccgacaaatg gttcgacgtg gaaatgtaat
    21841 gtggtgtccg gcatcagcca gccttgttca tccattttca gggtgatggc ggcaatctca
    21901 agcagcgcat cggttttggc gttaaatccg gctgtttcaa catcgatcac aacaggataa
    21961 aaaccacgaa aacggtcgca cagaccggta agttgagcgt tatcggacat ctgattctct
    22021 taatacggat aaattgcagc gcgcattatg acaaatatta cttgtcgatg cagtaaagat
    22081 gcgggcgcga tgagttcacg cccggcagga gattagttgc ccagaccgcg accggcgtct
    22141 ttctcttcga ttaattcaat tttgtaaccg tccggatctt ccacaaatgc gataaccgta
    22201 gtaccgcctt ttaccggacc cgcttcacgg gttacgttac ccccgttttg acggattttt
    22261 tcgcacgctt cagcggcgtt atctacgcta agcgcgatgt gaccataagc agtgccgagt
    22321 tcgtatttat ccacgcccca gttgtaggtc agttcaatca ctgcttcttc ggtttccggg
    22381 ccgtaaccaa caaacgccag tgagtatttg tattccgggt tttcgctggt acgcagcagt
    22441 ttcatgccca gcacgttggt ataaaaatcg atggagcgtt gcagatcgcc aacgcgcagc
    22501 atggtatgaa gaagacgcat ctttatatcc tcaaaatggc taacagattc aaaaagttgt
    22561 tttagtatag cggcggcttt gcgccgctcg caatgttgga ttacagcgtc gggtaatcag
    22621 tgtaaccttc agcaccgcca ccataaaaac tttcggcacg ctgcgggtta agctcagctt
    22681 tgcgctgcaa gcgggcgacc agatccgggt tcgcaatcca gtcacgacca aatgctaccg
    22741 catcaattaa ccctttgccg atcagcgttt cagctttttc tactgtgtat gcacctgcgc
    22801 cgataatcgg accgtggaaa cgggcgcgta ctttttcgcg aaacgcatca gtatatggtt
    22861 cacctcccgc ccaatctggt tctgacatat gaagataagc aatgccgcgt ttacccagtt
    22921 gttcaatcag atacagtgca tcggcttctt cattcgggcc gttatccgtg ttctggaaag
    22981 taccgattgg cgaaatgcga atgccaatgc gatcggcacc ccattcttca atcccggcat
    23041 cgaccacttc cagcaccaga cgcgcgcgat tttccacgct gccgccgtac tgatcggtac
    23101 gatggtttga agaaggggaa aggaactgat gcagcaaata accgtgagca gagtggagct
    23161 ctaccagatc aaaaccggct tcacgcgcgt tagcaatggc ctgacggaaa tcattgacga
    23221 tacccggaat ctcttccagt tcaagcgcac gcggcatgga tgtttcaaca cggatcgcct
    23281 gaccattttc atcgcgcaga gaagtacgtg ttcccgcgct aagtgctgaa ggcgctaccg
    23341 gtgcctgacc gccaggttgc aggctggcgt gagaaatgcg tccggtgtgc cacagctgta
    23401 cggccatatg accattttca gcatgaacgc cagcggtaat ttttttccat gcggcaattt
    23461 gttccgggct atggatgcca ggtgcacctg cgtatccttt tgcctgggca gaaatttgcg
    23521 tggcttcgct aataatcaaa ccggcactgg cacgttggcg atagtattcc gccatcaacg
    23581 gggtagggat gtcacccggt tcaatactgc gcagacgcgt cagcggtgcc ataaaaatac
    23641 ggtttgccgc cgtgatcgcg cccactttca gtggggaata cagtttttca gatgacataa
    23701 aggctcccgg tcgtctggtg ataaaaaatg cctgctaaac ggcaggcgtc gcaataatgt
    23761 tttttacatg ggccagcgcg ttttccagtg gctcgaaact gcgcgaaatt ttggcctgca
    23821 aattcgcacc aagccacagt gcgtaaagca cttgtgcctg ttgcagcggt tcgccacaaa
    23881 aggttaaaca atggttctca cggccatttt ccagcgcctg agagagcagg gcgatcacgc
    23941 cgcgagcccc tttatccatt gcgctgcgca tatcttctga cagatcgcac acttcggcag
    24001 agagttttac tgtcaggcaa ccactgatgg ttccatgttg gcaaaactgg ttcagtgttt
    24061 gctggtaata agccagtatg cggtcgcggt agttaccttc gccggattgc agcaactcag
    24121 tcagtcgctg gtgatatgcg gcgtaatggc gctcaagcat ggcaacgcca aacgcttctt
    24181 tagaacgaaa gtagtgatag aaggaccctt tcggcacttc agcggttttt aggagttcgc
    24241 ttagccccat cccggtgaat ccacgttgca ggcaaagttg ctcgcccgtc gccaggagat
    24301 gttcgcgagt atcatgttcg gtgtgtttgt tcatgcgttg gagtgtagta gaccagtcgg
    24361 tctagtgcaa gcaaagttgc tactttggac attaacagct tcaataatgg taataatctt
    24421 atctgaggag ggcgaggtga cggagcaatt agagttcttt cccgtccaga gcccgtgccg
    24481 gggaatttgc cagtctgacg aacggggatt ttgtcgcggc tgttttcgta gccgggatga
    24541 gcgttttaac tggaataaaa tgagcgatgg cgaaaaacaa gaagtgttgc gcctttgtcg
    24601 gcagcgatta atgcgcaaat tacgtgcaaa taagccagcg tcatcagacg aaccggagca
    24661 accatcactc ttttgagcct aatcttgcgt atactcctct catatctgat aagaggaagc
    24721 gattatggtt cagcgtatta ctattgcgcc gcaaggcccg gagttttccc attttgtgat
    24781 gggctactgg cgattgatgg actggaacat gtccgcccgc cagttggtca gttttattga
    24841 agagcatctg gatctcggcg tgaccaccgt ggaccatgct gatatttatg gtggctatca
    24901 gtgcgaagcg gcgtttggcg aggcgctgaa actggcacct cacctgcgtg aacggatgga
    24961 aatcgtcagt aaatgcggta tcgcgacgac cgcgtgtgaa gaaaacgtca ttggccatta
    25021 catcactgac cgcgatcaca tcattaagag cgccgaacag tcgctaatta atctcgcgac
    25081 cgatcatctg gatctgctgt taatccaccg accagacccg ttaatggatg ccgatgaagt
    25141 ggcggacgcc tttaaacatc tgcatcagag cggcaaagtg cgtcattttg gtgtatcgaa
    25201 ctttacacct gcgcaatttg cgctgttgca atcacgcctg ccatttaccc ttgccactaa
    25261 tcaggtggaa atatccccgg tgcatcagcc gttactgctg gatggcacgc tcgaccaact
    25321 gcaacaactg cgtgttcgtc cgatggcgtg gtcctgcctt ggtggtggtc gtctgtttaa
    25381 tgatgattat ttccagccgc tgcgtgatga actggctgtg gtggcagagg agttaaacgc
    25441 gggctcgatt gaacaggtgg tttacgcctg ggtattacgt ttaccgtcgc agccgctgcc
    25501 aattatcggc tcaggtaaaa ttgagcgcgt acgggcagca gtcgaagcag aaacactgaa
    25561 aatgacccgt caacaatggt tccgtatccg taaagcggca ctaggttacg acgtaccgta
    25621 agcactttta ggaatagccg ccgttcaaaa atgtgtcact ggtttacact tattcaggaa
    25681 tgcacaatga acggaggtcc tatgaaacgt tttagtctgg ccattctggc gctggttgtt
    25741 gcgaccggcg cacaagctgc cagtgaaaaa gtcgagatga acctcgtcac gtcgcaaggg
    25801 gttgggcagt caattggtag cgtcaccatt actgaaaccg ataaaggtct ggagttttcg
    25861 cccgatctga aagcattacc tcccggtgaa catggcttcc atattcatgc caaaggaagc
    25921 tgccagccag ccaccaaaga tggcaaagcc agcgccgcag aatccgcagg cgggcatctt
    25981 gatccacaaa ataccggtaa acatgaaggg ccagaaggtg ccgggcattt aggcgatctg
    26041 cctgcactgg tagtcaataa tgacggcaag gcgaccgatg ccgtcatcgc gcctcgtctg
    26101 aaatcactgg atgaagtcaa agacaaagcg ctgatagtcc acgttggcgg cgataatatg
    26161 tccgatcaac ccaaaccgct gggcggtggc ggtgaacgct atgcctgtgg tgtaattaag
    26221 taattaagag gccagcgtac cttgcggcgg tgcttgctca agttgcgaaa gcgagcagta
    26281 cagccgccag acaattgccg ccagttctcg ggcggcaggt tgatgatgac gggcaaggct
    26341 gtcgcaaatc cgctgtaatt cttcaagtgt ggccgccagt gatttttgct gaacgccacg
    26401 ctcactcatc actccccgca acagtgaaat acagttatcc cgtactcgcg ataacggatc
    26461 ggaacgcgat tcccagtcgc gcaattgcca gacaacatga gaacagttca gcaacactac
    26521 accccagcgt aataaccaac ggcgagccag cgcatcctgg ctgttactca actgactgac
    26581 gtgatgataa gtgagcgatt caaattcgct ttcactcagt gttggatggc ggcttagttg
    26641 atcgacaaaa tcccggcgca gcgcgcgaat atggcggcgg cttttacgag catccgatcc
    26701 tggacgcaga atggcgaacg ctaaccacgc caacgcgacg ccaacaattt ttgccagatt
    26761 atcgttaaga aaatcagcaa aatcatacac cgggggatta gtgacagcga taaacgaacc
    26821 cataaaaaca atcagttgcc cccacagtgc ggcaaatttg ggcatctgca atttaagaag
    26881 ctgcattgtc gccagcagtg gaaagagaaa cagtaaaaat tgccacagat cgctaatctg
    26941 caccatcagg ccaaatttga ccacaaagct gaatagcgaa agtaacacca gcgtgcgcat
    27001 cagcagtgac aaagacttaa acggtgctgc gacggcggag tagagtacgc agctaattgc
    27061 tgccagcgtt aaagcattgg caccggcatc ccattgcgaa gcaatactcc atgcgccaat
    27121 catcatcaac gtacaaaatg tacgcagccc gctccacata gcttcggcgt tatcggtatg
    27181 acgagccagg ccggatgtcc gtgggagtct ggcatgatca tctacaccgc tttgtagacg
    27241 atgtaattcc tgactacttt gcagataaag gcggcaaaaa taacgtagtc gctgccagaa
    27301 ggcgatgtgc cggtagtcgg tgacgttggt cgggcgtagt ggggagataa tacgtgcgac
    27361 ggtgtaaaca tctgtttgcg aactggcgag cgccgtcagc agctgttcga gaatttctcg
    27421 cgtggcatct ggcggtgagg gccagttgag caacatacgt cgcaggctgg agatgacact
    27481 ggtcatacgt aattgctggt ggagcagcgc attaaggcgt gcgttttgct ggcgaaaacg
    27541 atagtggctc cagaaagcct ggatacgcag caaattcatg gtcagtatct gcccaatcac
    27601 cccttcatgt gctgcacgaa tggcatcggt tgtttcaggc cgccagagta aactggcatg
    27661 ttccagtaat cgggcgtgca tgtttttcaa tgcggttaaa agggctgtag catcggaact
    27721 gctcggcagg atcatcatca tcatgccgcc gcacaaaata ccgactatca cctcgcaaac
    27781 acgcgcctga gcgatatccc acagctggct ggcctcagta atattaacca tcggaaaggc
    27841 gatgatggca gccgtgtagc ccgccagttg aaatgcatac gcgacgttat tcgtgaagtg
    27901 cgcacaggcc caggtacaaa agccaagcca cgccgacatg ctcaatagaa aaaaccacgg
    27961 ctcattgagc gtatgtccgg caagaagcag tgctgcaatg gctccgagca aactgccagc
    28021 gatgcgtccg aggcttttgc tgatgacacc gccaacggtg ggaaagctaa ccaccgcagc
    28081 cgaggtcatc gcccaatagg gttcatccag attcaaataa taggcaaccg tcagcgccag
    28141 acacatggca atggtattgc gtaacgcata acgccattgc gccagcgtgg ccctgaacca
    28201 gggcaaattg cgcaaggacc atgacgatgc gttcattatt gacctacggc aatgctacag
    28261 gtggtgcccg acaccagcgt gacatcgcct gggactttat ccagcgtaaa gcggacggga
    28321 acgcgttggg cgaggcgaac ccaggggacg ttaggtttca catccggaat aaggcttgag
    28381 tcactttcaa cgctctgatc ataaatcgcc cgaccgatac tggacacgtg accctgtaac
    28441 gttttgttat cactatagag ggtaatttgt gctggtgcac cttcgcggat atggcgcaac
    28501 ttggtttctt caaaataacc aatgacgtaa aacgagtggc tgtcaacaag ggcaaacagc
    28561 ggtttcccgg tgtcagcgta gtcgccgatg cgggtagtga gattagtcac ccatccactc
    28621 accggggcgc gaatttccgt ttgcgccagt tgccattgtg cctgtttcag cgtcgcctgt
    28681 gcggcatcaa cgctggcctg catcgcttta acattgaggt tagcggtatc gagttcttcg
    28741 gcagaaataa aattttgtga gagatgacga cgacgattcg cttcgttatt ggcttttgcg
    28801 aggtcagatt gcgctttcgc cagctgagcc tgtgcgttca gctcggcgat ctgaaagggc
    28861 gttttatcga tcgtgagcag aagatccccc gcgttaacca gctggttgtc ttttatattc
    28921 agctcaacaa tacgtcccga cacctgtggg gtgatagaaa cctgttctgc gcgtattttc
    28981 ccgtcgcgtg tccacggaga ttgcatgtaa taattccaca gccaccatcc ggcaagaacc
    29041 gcaactaccg ctacaatgat tgttgagaaa tacttaattg ttttaattga catagttacc
    29101 acgcaatcag tattgccaga gcaaggcaaa cgcaaatcgc aaacagcgat aaatccatta
    29161 acaagggatg ccagatgtca ccagcgtaga tccagccacg aagcaggcgg tgtatgacaa
    29221 gccagatgac gaatccaaac gcgaaggctt tgaaaaacgg aggaaagtag acggacgcac
    29281 cgaacaccag atcttgtaag ggcaatcctg ttgcattgag cataaacttc acaaagtaga
    29341 ttcctttacg acagaatata ttgcgttaga ttaataaata ttctttaagt gcgaaaaatt
    29401 tacgcgcaat ttctgaaaaa tatgtctgac ggtaaccaaa tgcagcaata catttgtttt
    29461 agcaatacaa ttgctgcaca ctattctaaa agccgcataa tatcttagca agctaattat
    29521 aaggagatga aattggaatc gccactaggt tctgatctgg cacggttggt gcgcatatgg
    29581 cgtgctctga tagaccatcg cctgaaaccg ctggagttaa cacaaaccca ttgggttacg
    29641 ttacacaata tccatcagtt acctccagac cagtcgcaaa ttcaactggc aaaagcgatt
    29701 ggcatcgagc agccatcact ggtccgtacg ctggaccaac tggaagaaaa agggttaatt
    29761 tcgcgtcaaa cttgtgccag cgatcgtcgg gctaaacgta ttaaactgac ggaaaaggca
    29821 gagccactga tcagcgaaat ggaggctgtt attaacaaaa cccgcgcgga aattttacat
    29881 ggcatctccg cagaggaact ggaacaactg attaagctca tcgcaaaact tgagcataat
    29941 atcattgagt tacaggccaa agggtgaaat gaagggggcg tgtggtcagt aacctgacca
    30001 cacgcaaact tatttagcgc ggggaaacgg tcacctgact gccattgctg gccagtacga
    30061 cacgttggcc tggagagaaa tgagtgttcc cttgtttctg taccaccatg atggtgttgc
    30121 catcatcttt acgaatttcc agctcgacac cctgcgtttt gttcattgca ctctgtacgc
    30181 cctgaccggc tacaccacct gcaacggccc ctgctgcagt agccagagaa cgcccggttc
    30241 cgccaccaat agtatttccc aggaaaccac caagtacagc accgccaatt gcgccgataa
    30301 cgttggaatc atcaccgccc tgaatctgta cctgacgtac attaacgatg gtgccatagc
    30361 tgacattctg tacttgtttc gcttcagaag cggtataaac atcccctgac agggtgtcgt
    30421 tattaacaca accgacaaga gacagaccta ccattgaaac aaccaatacg cgtttaatca
    30481 ttgaaaaatc tcctgttcac catgaaacgc cacgcaagca tccctcatgg tcaaagtata
    30541 tggcatatgt gaatccatgg ttacatgttc taccaaatat gagcaaatca taatgaaagt
    30601 aggatcaacc aattataaac aaaatattca tgatgattat tgatttgaag ataatgtttt
    30661 actaccaacg gtaaaaattg gtcattccgc gtggtattca cgaaaagttt atgtttgagt
    30721 ggtgcgcaaa cgtcagattg aaaaaggatg aactatgaaa tcgggccgct ttattggcgt
    30781 tatgtcaggc accagccttg atggtgttga tgttgtgtta gcgacaattg atgaacaccg
    30841 ggtcgcacag ctggcaagtt tgagctggcc gatcccggtg tctctgaaac aggctgtact
    30901 ggatatttgc cagggccagc agcttacact ttcgcagttt ggacagcttg atactcaact
    30961 cgggcgactt tttgctgatg cggtcaatgc cttgcttaag gaacaaaacc tgcaggcgag
    31021 agatatcgtt gcgatcggct gtcacggtca aaccgtctgg cacgaaccga cgggcgtggc
    31081 accacacact ttacagattg gcgataacaa tcaaattgtg gcgcgcaccg gaattacggt
    31141 tgtcggtgat tttcgccgtc gcgatattgc cctgggagga caaggtgcac cgctggtacc
    31201 tgcgttccat catgcgctgc tggctcaccc aaccgagcga cgaatggtgc tcaatattgg
    31261 cggcatcgcc aatctgtcac tgctcattcc tggccagccg gttgggggct acgataccgg
    31321 tcctggtaac atgctgatgg atgcctggat ctggcgtcag gccggtaaac cttacgataa
    31381 agatgccgag tgggcacggg cgggtaaagt tattctccca ctgctgcaaa atatgctcag
    31441 cgacccatat ttctcgcaac ccgcaccgaa aagcaccgga cgcgaatact ttaactacgg
    31501 ctggctggag cgccatttgc gccattttcc gggggttgat ccccgtgatg tgcaggccac
    31561 agtggcagaa ctcaccgccg tgaccatttc tgaacaagtt ttgttgagcg gtggctgcga
    31621 acgattgatg gtatgtggtg gaggtagtcg taatccgcta ctcatggcgc gtctggcggc
    31681 attactgcca ggcacagaag tcaccaccac cgatgccgtt ggcattagtg gcgatgacat
    31741 ggaagcattg gcgttcgcct ggcttgcctg gcgaacgctg gcgggattac caggaaatct
    31801 gccttccgtc actggcgcaa gccaggagac ggtactgggg gctattttcc ccgctaaccc
    31861 gtgatatcag agttaactga atttttctta ccgcgtctgc cgttacactt ggaacgttag
    31921 ggagggcgta ttgccctcca gaccaggaaa gtcttcggga tatgtctatg aaaaaactgt
    31981 tactgatctg tttgccggtg cttctcaccg gctgtagcgc gttcaatcaa ctggttgagc
    32041 gcatgcaaac cgatacgctt gaataccagt gtgatgaaaa accgttgacg gtcaaactga
    32101 ataatccgcg ccaggaagtc agttttgttt acgataatca actactgcat ctcaaacagg
    32161 gcatttcagc gtctggtgca cgttacaccg acggaatcta tgttttctgg tcgaaaggcg
    32221 aggaagcgac tgtctataaa cgcgaccgca tcgtcttgaa taactgtcag ttacaaaatc
    32281 cgcagcgttg agatttttcc aggggcggcg cacaatagcg tcacccactg acaatccgta
    32341 aagaaaacca tgtctgataa cgacgaattg cagcaaatcg cgcatctgcg ccgtgaatac
    32401 accaaaggcg ggttacgccg ccgcgatcta cccgccgatc cattaaccct ttttgaacgt
    32461 tggctctctc aggcttgtga agccaaactg gctgacccta ccgcgatggt ggtcgctacc
    32521 gtggatgaac atggtcagcc ttatcagcgc atcgttttac tcaaacatta cgacgaaaaa
    32581 ggcatggtgt tttacaccaa cctcggcagc cgtaaagcac atcaaatcga aaataatccg
    32641 cgcgttagcc tgctgttccc gtggcatacc cttgaacgcc aggtgatggt gatcggtaaa
    32701 gcggaacgac tttcgactct cgaagtgatg aaatattttc atagccgccc gcgtgatagc
    32761 cagattggtg catgggtttc gaagcagtcc agtcgcattt ctgcccgcgg tatccttgaa
    32821 agtaaattcc tggagctgaa gcagaagttt caacagggcg aagtgccatt gccaagtttt
    32881 tggggtggtt ttcgcgtcag ccttgaacag attgagttct ggcagggcgg tgagcatcgc
    32941 ctgcatgacc gctttttgta ccagcgtgaa aatgatgcgt ggaagattga tcgtcttgca
    33001 ccctgaaaag atgcaaaaat cttgctttaa tcgctggtac tcctgattct ggcactttat
    33061 tctatgtctc tttcgcatct ggcgaaaagt cgtgtaccgg caaaggtgca gtcgttatat
    33121 acatggagat tttgatggca agcagtaact tgattaaaca attgcaagag cgggggctgg
    33181 tagcccaggt gacggacgag gaagcgttag cagagcgact ggcgcaaggc ccgatcgcgc
    33241 tctattgcgg cttcgatcct accgctgaca gcttgcattt ggggcatctt gttccattgt
    33301 tatgcctgaa acgcttccag caggcgggcc acaagccggt tgcgctggta ggcggcgcga
    33361 cgggtctgat tggcgacccg agcttcaaag ctgccgagcg taagctgaac actgaagaaa
    33421 ctgttcagga gtgggtggac aaaatccgca agcaggttgc cccgttcctc gatttcgact
    33481 gtggagaaaa ctctgctatc gcggcgaaca actatgactg gttcggcaat atgaatgtgc
    33541 tgaccttcct gcgcgatatt ggcaaacact tctccgttaa ccagatgatc aacaaagaag
    33601 cggttaagca gcgtctcaac cgtgaagatc aggggatttc gttcactgag ttttcctaca
    33661 acctgttgca gggttatgac ttcgcctgtc tgaacaaaca gtacggtgtg gtgctgcaaa
    33721 tcggtggttc tgaccagtgg ggtaacatca cttctggtat cgacctgacc cgtcgtctgc
    33781 atcagaatca ggtgtttggc ttgaccgttc cgctgatcac caaagcagac ggcaccaaat
    33841 ttggtaaaac tgaaggcggc gcagtctggt tggatccgaa gaaaaccagc ccgtacaaat
    33901 tctaccagtt ctggatcaac actgcggatg ccgacgttta ccgcttcctg aagttcttca
    33961 ccttcatgag cattgaagag atcaacgccc tggaagaaga agataaaaac agcggtaaag
    34021 caccgcgcgc ccagtatgtg cttgcagaac aggtgacacg tctggtgcat ggtgaagaag
    34081 gtttgcaggc ggcaaaacgt attaccgaat gcctgttcag cggttccttg agtgcgctga
    34141 gtgaagcgga cttcgaacag ctggcgcagg acggcgtacc gatggttgag atggaaaagg
    34201 gcgcagacct gatgcaggcg ctggtcgatt ctgaactgca accttcccgt ggtcaggcgc
    34261 gtaaaactat cgcctccaat gccatcacca ttaacggtga aaaacagtcc gatcctgaat
    34321 acttctttaa agaagaagat cgtctgtttg gtcgttttac cttactgcgt cgcggcaaaa
    34381 agaattactg tctgatttgc tggaaataat gcattaagtg gaaaggggga gtgagaaatc
    34441 actccccctg gtttttatac agggaacatg atgaaaaata ttctcgctat ccagtctcac
    34501 gttgtttatg gtcatgcggg taacagtgcg gcagagtttc cgatgcgccg cctgggcgcg
    34561 aacgtctggc cgctgaacac cgttcaattt tctaatcaca cccaatacgg caaatggacc
    34621 ggttgcgtga tgccgcccag ccatttaacc gaaattgtgc aaggcattgc cgccattgat
    34681 aaattacaca cctgtgatgc cgtattaagt ggctatctgg gatcggcgga gcagggtgaa
    34741 catatcctcg gtatcgttcg tcaggtgaaa gcagcgaatc cacaggcgaa atatttttgc
    34801 gatccggtaa tgggtcatcc ggaaaaaggc tgtatcgttg caccgggtgt cgcagagttt
    34861 catgtgcggc acggtttgcc tgccagcgat atcattgcgc cgaatctggt tgagctggaa
    34921 atactctgtg agcatccggt aaataacgtc gaagaagcgg ttctggcagc gcgcgaactc
    34981 attgcgcaag ggccacaaat tgtgttggtt aaacacctgg cgcgagctgg ctacagccgt
    35041 gaccgttttg aaatgctgct agtcaccgcc gatgaagcct ggcatatcag ccgtccgctg
    35101 gtggattttg gtatgcgcca gccggtaggt gttggtgatg tgacgagcgg tttactgctg
    35161 gtgaaactgc ttcagggggc aacgctgcag gaggccctgg aacatgtgac cgctgcagta
    35221 tacgaaatca tggtgaccac aaaagcaatg caggaatatg agctgcaagt ggttgctgct
    35281 caggatcgta ttgccaatcc agaacattat ttcagcgcaa caaagctctg aaatatctca
    35341 tttcggccca caacgacctg tgggccgatg gctattactt taagccttcc gctgacagcg
    35401 cgtcttgtac ttccggacgt tcagccatac gttgcataaa tgccgcaatg tgctctaacc
    35461 cttccagatt cagtttcacc gcgtatgccc agcgcagaac cgtaaacaga taggcatcag
    35521 caattgtgaa tcgttgcccg cagatccagt gctcatcctt cagggcctcg ttcacatatt
    35581 gcagcttctt ctccagctgc gcgcgaactg tcggtttgta ctcttccggt gtatcagggc
    35641 gaaacagagg tgtgaaacct ttatgcagct cggtggcgat gtaattcagc cattcgatgg
    35701 ttttatagcg ggaaatactg tttaccggtg ccagcaactg gcggtcgggg acgctgtcgg
    35761 caagatactg cataatcgct acgccttccg tcagcaaagt accatcgtcc agcagcaatg
    35821 caggtacctg tcccttaggg ttaacggcaa agtaatcgtc accgttttcg agacgttttt
    35881 tcattaaatc cacactgacg agcgtaaaat cctttccgct ctcacgcagg gtgatatggg
    35941 aagcgagaga gcaggcgccc ggtttgtaga acaatttcat cggtaactcc ttttgtctgt
    36001 ggtttaaagt atggtagtgc gttgctgaac aaaaaaaaag ccgctaacga aaagttagcg
    36061 gcttgtaaat gagtttccct gaattttacg ctacggctgc tttcgccgct ttgtctgcag
    36121 cgtcatcctg cgtcatgcgg tgcagtttcg gcgcggtaaa cagcatcagt actgcaataa
    36181 cggcagtagc gacaccaatc tgcaagaata cgcgaccata gacttccagt gacatcagcg
    36241 gatcggtaac gttatccggc acagccatca tacctgcaac ataaccacca atcaggtttg
    36301 caccggcagt ggtcaggaac cagctaccca taatgaagcc catcagacgc tgcggaacga
    36361 gttgtgcaac cattgccaga cccaggccag agatcatcag ttccccgata ctctgcaggc
    36421 catagctcgc gaccagccag cttacagaca cgataccagc gtcagacgcg aatttcgcac
    36481 ccagcggcag aatcaggaac gcaccagaac acatcaccat gccgatagca aacttggttg
    36541 gcatcggcag ggtatcgccc atcttgttat agatagcggc cagaatcggg ctaccaatga
    36601 tgatccagaa cgggttcagt gcctgatact gctcaggttc tacggccagg cccagaatgg
    36661 tgtgttcaac gttacgaatc gcaaagaagt tcagtgacgt tggcatctgg ctataaagca
    36721 cgaagaagat aatggcttcg agcatcagga tgaaggcaac gatcatttta cgacgcgcag
    36781 cacctttcat cgcgaaggct tctttaccga agataaccac aataccgaag gcaacaacgc
    36841 ccagcgccat acgcgcaact tcctgattgt gcagcagcca ggtggcgata gcgatcagtg
    36901 ccacaacacc aataatggtc agcagcaggt tacggtagtt gataggctcg aagtctggtt
    36961 ttgaaccgta ctgtttaacc caacgttggc agaaggcgaa gttaacgata gtgatcagca
    37021 ggcctacaac gctcaacgca aacgcaacac tccagccgta tttcgcggcc agccacggcg
    37081 tagcaatcat agagaagaaa gagccgatgt tgacggacat gtagtacatg gtgaatgcac
    37141 cgtccagacg cgggtcgttt ttctcatagc atgtagaaag cagagaagac gggttagctt
    37201 taaacaggcc gttaccgacc gcaatagccg ccatacccat ataaacgata ccggcgtcgt
    37261 gaccagacca ggcaaccaga gcataaccaa tcgccagcac aatagcgccg agcataatta
    37321 cgcgtttagt acccagtacc ttgtcaccta accagccgcc gatagcgacc agaccataaa
    37381 ccagggcact aaaggaagag aaaagggtga ttgaatccgc ttcagacata cccagttgtt
    37441 taaccaggta aacagccata attccttgta ggccgtaata accaaaacgt tcccataact
    37501 caatcgagaa gatgagatag aacgccttcg gttgtttaaa agcgttcaaa ctgacgcttt
    37561 cagttggttt ttggtttgca gtggacactt ttacctcttt ttttacatcc catattaacg
    37621 ggggtgcttt ctcgcgttat gtctaaaaaa catacgcgca attgttatag tgggagggga
    37681 aacggcaggt aatgttcact atcttgcact ttcagacaag tccttgtaat aatctgttac
    37741 atataactga ggcggggaat tcaaccattc cgggaaatgt tatccagcgt taaatttttc
    37801 aaaaaacgta acggcagatt ttttcactac cctgagaggg tgatgatggc ttaacggcga
    37861 tatgttctac tatttagcgt ttttcctagt gagatagtcc agtttctgaa aaatagccag
    37921 tgtaatgttt tgtaggtcaa tatttgttgt gtgtgt
//
LOCUS       DAPOXO010000046        37369 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.046, whole genome shotgun sequence.
ACCESSION   DAPOXO010000046 DAPOXO010000000
VERSION     DAPOXO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37369
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.046"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            81..1220
                     /gene="arnB"
                     /locus_tag="ROH59_002730"
     CDS             81..1220
                     /gene="arnB"
                     /locus_tag="ROH59_002730"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HDX4805189.1"
                     /translation="MSGFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DRDTLMVTPEAIEAAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     HTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALATLPF
                     QPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ"
     gene            1224..2192
                     /gene="arnC"
                     /locus_tag="ROH59_002731"
     CDS             1224..2192
                     /gene="arnC"
                     /locus_tag="ROH59_002731"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HDX4805190.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTAACESLGKEYEIL
                     LIDDGSSDNSAHVLVEASQAEGSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            2192..4174
                     /gene="arnA"
                     /locus_tag="ROH59_002732"
     CDS             2192..4174
                     /gene="arnA"
                     /locus_tag="ROH59_002732"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HDX4805191.1"
                     /translation="MKTVVFAYHDMGCLGIEALLSAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKALPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NARRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS"
     gene            4171..5061
                     /locus_tag="ROH59_002733"
     CDS             4171..5061
                     /locus_tag="ROH59_002733"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HDX4805192.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHE
                     VGLHAWDHHAWQAHSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGTPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRIQRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGTLPLGQVV
                     RGNIAGREGWLGCQQMAGSH"
     gene            5061..6713
                     /gene="arnT"
                     /locus_tag="ROH59_002734"
     CDS             5061..6713
                     /gene="arnT"
                     /locus_tag="ROH59_002734"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HDX4805193.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALMTWFT
                     LRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYLPVIIAGSLPWLGLLP
                     GALYAGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFAPLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRDEDINSLAIPPADAIDRQGRLVLIQYRPK"
     gene            6710..7045
                     /gene="arnE"
                     /locus_tag="ROH59_002735"
     CDS             6710..7045
                     /gene="arnE"
                     /locus_tag="ROH59_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HDX4805194.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFAAVNKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSLRHWCGVAFIIG
                     GIVILGSTV"
     gene            7045..7431
                     /gene="arnF"
                     /locus_tag="ROH59_002736"
     CDS             7045..7431
                     /gene="arnF"
                     /locus_tag="ROH59_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416761.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HDX4805195.1"
                     /translation="MGLMWGLFSVIIASAAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPTTKQRY"
     gene            complement(7425..7691)
                     /gene="pmrD"
                     /locus_tag="ROH59_002737"
     CDS             complement(7425..7691)
                     /gene="pmrD"
                     /locus_tag="ROH59_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311174.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HDX4805196.1"
                     /translation="MEWLVKKSCCNKQNNRHVLMLCDAGGAIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASCYSPDEWERQCKAAGKTQ"
     gene            complement(7801..9156)
                     /gene="menE"
                     /locus_tag="ROH59_002738"
     CDS             complement(7801..9156)
                     /gene="menE"
                     /locus_tag="ROH59_002738"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HDX4805197.1"
                     /translation="MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASSF
                     AAQGVVAGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPEGENTFPALTSLHIQQVEGVHAVAWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAEGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNDEVWLRAASMAEGYWRNGQRVPLVNDEGWYAT
                     RDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVVEYDQQTVDLGEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQ
                     D"
     gene            complement(9153..10115)
                     /gene="menC"
                     /locus_tag="ROH59_002739"
     CDS             complement(9153..10115)
                     /gene="menC"
                     /locus_tag="ROH59_002739"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HDX4805198.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEDAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     PDFAFVAEEGVRAVVIKPTLTGSLEKVREQVKAAHALGLTAVISSSIESSLGLMQLAR
                     IAAWLTPDTIPGLDTLDLMQVQQVRRWPGSPLPLVDVDALERLL"
     gene            complement(10115..10972)
                     /gene="menB"
                     /locus_tag="ROH59_002740"
     CDS             complement(10115..10972)
                     /gene="menB"
                     /locus_tag="ROH59_002740"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HDX4805199.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(10987..11745)
                     /gene="menH"
                     /locus_tag="ROH59_002741"
     CDS             complement(10987..11745)
                     /gene="menH"
                     /locus_tag="ROH59_002741"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HDX4805200.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLY
                     VDLPGHGGSATISVDGFDDVTDLLCKTLVSYNILNFWLVGYSLGGRVAMMAACQELAG
                     LCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQ
                     RRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAADCHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(11742..13412)
                     /gene="menD"
                     /locus_tag="ROH59_002742"
     CDS             complement(11742..13412)
                     /gene="menD"
                     /locus_tag="ROH59_002742"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HDX4805201.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     SAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGISWQQRLGDWWQDDKPWLREAPRRESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     ELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKSERGRFYLMPQNVHFEHAAAMFELKY
                     HRPQNWQELETTLVDAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13501..14796)
                     /gene="menF"
                     /locus_tag="ROH59_002743"
     CDS             complement(13501..14796)
                     /gene="menF"
                     /locus_tag="ROH59_002743"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HDX4805202.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQVYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGYLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIKAKEFIATLVSIKPLPGLHLTT
                     TREQHWPDKTGWTLLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTRTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNIVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(14875..15180)
                     /gene="elaB"
                     /locus_tag="ROH59_002744"
     CDS             complement(14875..15180)
                     /gene="elaB"
                     /locus_tag="ROH59_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HDX4805203.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15235..15696)
                     /locus_tag="ROH59_002745"
     CDS             complement(15235..15696)
                     /locus_tag="ROH59_002745"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX4805204.1"
                     /translation="MIDWQDLHHSDLSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     EGENRHILGWHNGTLVAYARILKSDDELQPVVIGRVIVSEALRGEKIGQQLMSKALES
                     CTRRWPEKPIYLGAQAHLQNFYGQFGFIPVTDIYEEDGIPHIGMAREVIQA"
     gene            15761..16678
                     /gene="rbn"
                     /locus_tag="ROH59_002746"
     CDS             15761..16678
                     /gene="rbn"
                     /locus_tag="ROH59_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311183.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HDX4805205.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPHGIREFVE
                     TALRISGSWTDYPLEIVEISTGEIFDDGLRKVTAYPMEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQELKAGKTIMLDDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALELAKGVDVMVHEATLDMAMEAKANSRGHSSTRQAAALAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFAVFSI"
     gene            complement(16799..18541)
                     /locus_tag="ROH59_002747"
     CDS             complement(16799..18541)
                     /locus_tag="ROH59_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDX4805206.1"
                     /translation="MRNKNIIMLLISSLILSGCGPEPEDKKSQQQQSTTPTDQQVLAA
                     QQAATKVAEQSAAKAAADAKALAQQEVQQYSDKQALLGRLQAAPKYQHAAREKAASQI
                     ANPATARYQQFDDNPVKQVAQNPLATFSLDVDTGSYANVRRFLNQGLLPPPDAVRVEE
                     IVNYFPSDWDIKDKQSIPASKPIPFAMRYELAPAPWNEQRTLLKVDILAKDRKSEELP
                     ASNLVFLIDTSGSMISDERLPLIQSSLKLLVKELREQDNIAIVTYAGDSRIALPSISG
                     SHKAEINAAIDSLDAEGSTNGGAGLEMAYQQAAKGFIKGGINRILLATDGDFNVGIDD
                     PKSIESMVKKQRESGVTLSTLGVGDSNYNEAMMVRIADVGNGNYSYIDTLSEAQKVLN
                     SEMRQTLITVAKDVKAQIEFNPAWVTEYRQIGYEKRQLKAEDFNNDNVDAGDIGAGKH
                     ITLLFELTLKGQKASIDKLRYAPDNKSAKSDKTKELAWLKIRWKSPQGKESQLVEFPL
                     ASAIKAPSEDMRFRAAVAAYGQKLRGSEYLNNTSWQQIKQWAQKAKGEDPQGYRAEFI
                     RLIGLAKDLDNSQN"
     gene            18679..19650
                     /locus_tag="ROH59_002748"
     CDS             18679..19650
                     /locus_tag="ROH59_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDX4805207.1"
                     /translation="MKKINFAFIILFLFSLPLIIFYQPWVNALPPTPRHASPEQLEKT
                     VRYLTQTVHPRSADNIDNLNRSAEYIKEVFISSGARVTAQDIPITGGPYKNIVANYGP
                     ADGPLIIIGAHYDSVSSYENDQLTYTPGADDNASGVAGLLELARLLQQQAPKTGVQLV
                     AYASEEPPFFRSDEMGSAVHAASLERPVKLMIALEMIGYYDSTPGSQDYPSPAMSWLY
                     PDRGDFIAVVGRMQDINAVRQVKAALLSSRDLSVYSMNAPGFIPGIDFSDHLNYWQYD
                     IPAVMITDTAFYRNKQYHFPGDIADRLNYQKMAQVVDGVTTLLYNSK"
     gene            19753..20256
                     /locus_tag="ROH59_002749"
     CDS             19753..20256
                     /locus_tag="ROH59_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDX4805208.1"
                     /translation="MGMIGYFAEIDSEKINQLLESTKKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLES
                     LDRSELRKQFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
                     ALTVIVG"
     gene            complement(20323..21780)
                     /gene="nuoN"
                     /locus_tag="ROH59_002750"
     CDS             complement(20323..21780)
                     /gene="nuoN"
                     /locus_tag="ROH59_002750"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HDX4805209.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM"
     gene            complement(21787..23316)
                     /gene="nuoM"
                     /locus_tag="ROH59_002751"
     CDS             complement(21787..23316)
                     /gene="nuoM"
                     /locus_tag="ROH59_002751"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HDX4805210.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALVTMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAIQALVFVHYNATGVWTFNYEELLNTPMSNG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(23480..25321)
                     /gene="nuoL"
                     /locus_tag="ROH59_002752"
     CDS             complement(23480..25321)
                     /gene="nuoL"
                     /locus_tag="ROH59_002752"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HDX4805211.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQAYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(25318..25620)
                     /gene="nuoK"
                     /locus_tag="ROH59_002753"
     CDS             complement(25318..25620)
                     /gene="nuoK"
                     /locus_tag="ROH59_002753"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HDX4805212.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(25617..26171)
                     /gene="nuoJ"
                     /locus_tag="ROH59_002754"
     CDS             complement(25617..26171)
                     /gene="nuoJ"
                     /locus_tag="ROH59_002754"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HDX4805213.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(26183..26725)
                     /gene="nuoI"
                     /locus_tag="ROH59_002755"
     CDS             complement(26183..26725)
                     /gene="nuoI"
                     /locus_tag="ROH59_002755"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HDX4805214.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(26740..27717)
                     /gene="nuoH"
                     /locus_tag="ROH59_002756"
     CDS             complement(26740..27717)
                     /gene="nuoH"
                     /locus_tag="ROH59_002756"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HDX4805215.1"
                     /translation="MSWISPELIEILLTVLKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(27714..30440)
                     /gene="nuoG"
                     /locus_tag="ROH59_002757"
     CDS             complement(27714..30440)
                     /gene="nuoG"
                     /locus_tag="ROH59_002757"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HDX4805216.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSAE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(30493..31830)
                     /gene="nuoF"
                     /locus_tag="ROH59_002758"
     CDS             complement(30493..31830)
                     /gene="nuoF"
                     /locus_tag="ROH59_002758"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDX4805217.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDSGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGAWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(31827..32327)
                     /gene="nuoE"
                     /locus_tag="ROH59_002759"
     CDS             complement(31827..32327)
                     /gene="nuoE"
                     /locus_tag="ROH59_002759"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HDX4805218.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(32330..34132)
                     /gene="nuoC"
                     /locus_tag="ROH59_002760"
     CDS             complement(32330..34132)
                     /gene="nuoC"
                     /locus_tag="ROH59_002760"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HDX4805219.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSY
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(34226..34888)
                     /gene="nuoB"
                     /locus_tag="ROH59_002761"
     CDS             complement(34226..34888)
                     /gene="nuoB"
                     /locus_tag="ROH59_002761"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HDX4805220.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(34904..35347)
                     /gene="nuoA"
                     /locus_tag="ROH59_002762"
     CDS             complement(34904..35347)
                     /gene="nuoA"
                     /locus_tag="ROH59_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HDX4805221.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETDSIANRQR"
     gene            complement(35977..36915)
                     /gene="lrhA"
                     /locus_tag="ROH59_002763"
     CDS             complement(35977..36915)
                     /gene="lrhA"
                     /locus_tag="ROH59_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HDX4805222.1"
                     /translation="MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPST
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQTMESYHNPWQYSPMSAPEGDDSLLIERDIE"
BASE COUNT         9029 a        10179 c         9510 g         8651 t
ORIGIN      
        1 tgctccaaat ggcaaaatat acacaacact ctttatagca aatataagtg gacaggtatt
       61 caatgacgga tggaaaaaca atgtcaggat ttttgccttt ttcgcgacca gcaatgggcg
      121 tagaggaact cgctgcagtt aaagaggttc tcgaatccgg ttggatcaca accggtccga
      181 agaatcaggc gcttgaacaa gctttttgcc agttgacggg aaatcagcat gccatcgcgg
      241 tcagttcagc caccgccgga atgcatatca cgctaatggc gttggaaatt ggcaagggcg
      301 atgaagtgat tacgccttcc ctgacctggg tttcaaccct caatatgatt tccttgctgg
      361 gtgcaacgcc ggtaatggtg gatgtcgacc gcgatacgct gatggtcacg cctgaagcga
      421 tcgaagcagc cattacacca cgcactaaag ccatcattcc ggtgcattat gccggtgcgc
      481 cagcagatat tgacgccatt cgcgccattg gcgaacgtta cggcatcgca gttatcgaag
      541 atgctgccca tgccgtaggt acgtattaca aagggcgaca tattggcgca aaaggtaccg
      601 ctattttttc gtttcacgcc atcaaaaata ttacctgtgc ggaaggtggc ctgattgtta
      661 ctgataatga aaatcttgcc cgccagctgc ggatgctgaa atttcacggt ctgggtgtcg
      721 atgcctatga cagacatacc tggggccgtg caccgcaggc tgaagtctta acgccgggct
      781 ataagtacaa tctgaccgat attaacgccg cgattgccct gacacagtta gtcaaattag
      841 agcacctcaa cacccggcgg cgcgaaattg cccagcaata tcagcaagca ctggcaactc
      901 tcccctttca gccattaagc cttcccgcct ggccgcacgt tcacgcctgg catctgttta
      961 ttattcgtgt cgatgaacaa cgttgtggta tcagtcgcga tgcgttgatg gaagcgttaa
     1021 aagaaagagg cattggtacc gggttacatt tccgcgctgc tcacacacaa aaatattatc
     1081 gcgagcgttt tcccacgctg tcgttaccga ataccgaatg gaatagcgaa cgcatctgtt
     1141 cattgccgct gttcccggat atgaccaccg ccgatgccga ccgcgtcatc acagcccttc
     1201 agcaactcgc aggacaataa gccatgtttg aaatccaccc tgttaagaaa gtctcggtgg
     1261 ttattcccgt ttataacgag caggaaagct taccggaatt aatcaggcgc accaccgcag
     1321 cctgtgaatc actggggaaa gagtatgaaa tcctgctgat tgatgacggc agtagcgata
     1381 attccgcgca tgtgctggtc gaagcctcac aagcggaggg cagccatatt gtgtctattt
     1441 tgcttaaccg caattacggg caacattcag cgattatggc gggattcagt cacgtcaccg
     1501 gcgacttaat tattaccctc gatgccgatc tccagaatcc gccagaggag atcccccgtc
     1561 tggtggcaaa agccgatgaa ggttacgacg tggtagggac tgtacgccag aaccgccagg
     1621 acagctggtt tcgtaaaacc gcttcgaaga tgattaaccg gcttattcag cgcaccaccg
     1681 gcaaagcgat gggtgactat ggttgtatgc tgcgcgccta tcgccgtcat attgtcgatg
     1741 cgatgttgca ctgccatgaa cgcagcacct ttatcccgat tctggcgaat atcttcgccc
     1801 gccgtgccat tgaaattcca gtgcaccatg ccgagcgtga gtttggtgaa tccaaataca
     1861 gctttatgcg cctgattaat ttgatgtacg acctggtgac ctgccttacc acaacgccgc
     1921 tacgtatgtt gagtttgctc ggcagcatta ttgcgattgg cggttttagc attgcggtgc
     1981 tgctggtgat tttacgcctg accttcggac cacaatgggc ggcagaaggc gtctttatgc
     2041 tatttgccgt gctgtttact tttattggcg ctcagtttat cggcatggga ttgctcggtg
     2101 aatatatcgg caggatctac accgatgtcc gcgcccgccc ccgctatttt gttcagcaag
     2161 ttatccgtcc atccagcaag gaaaatgaat aatgaaaacc gtcgtttttg cctaccacga
     2221 tatgggatgc ctcggtattg aagccctgct gtctgccggt tacgaaatta gcgccatttt
     2281 tacccatact gataaccccg gtgaaaaagc cttttatggt tcggttgccc gactggcagc
     2341 ggaaagaggc attccagttt atgcgccgga taacgttaat catccgctgt gggtggaacg
     2401 cattgcccaa ctatcaccag aggtgatttt ctctttttat tatcgccatc ttatttgcga
     2461 tgagattttg cagctcgctc cgagaggtgc atttaatctg catggttcgc tgttaccaaa
     2521 atatcgtggt cgcgcgccgc tgaactgggt gctggtgaac ggtgaaacgg aaactggcgt
     2581 tacattgcac cgaatggtga aacgtgccga tgccggggcc attgtggcac aactgcgcgt
     2641 tgccattgcg ccagacgata tcgccattac gctgcatcat aaattgtgcc atgccgcgcg
     2701 ccagctactg gaacagacat tacccgccat taaacacggt aatattctgg aaatcgccca
     2761 gcgcgaaaac gaagccacct gttttggtcg cagaacgccg gatgacagtt tcctcgaatg
     2821 gcataagccg gcatccgtac tgcacaacat ggtgcgtgcc gttgccgatc cgtggccggg
     2881 tgccttcagc tatgttggca atcagaaatt caccgtctgg tcgtcgcgtg ttcatcctca
     2941 tgccagcaaa gcactgccgg ggagcgtgat ttctgttgca ccactgctga ttgcctgtgg
     3001 cgatggcgcg ctggaaatcg tcactggaca ggcgggcgac ggcattacta tgcagggctc
     3061 gcaattagcg cagacgctgg gcctggtgca aggttcacgc ttgaatagcc agcctgcctg
     3121 tgccgcccga cgccgtaccc gggtactcat cctcggggtg aatggcttta ttggcaacca
     3181 tctgacagaa cgcctgctgc gcgaagatca ttatgaagtt tacggtctgg atattggcag
     3241 cgatgcgata agccgttttc tgaatcatcc gcattttcac tttgtcgaag gcgatatcag
     3301 tattcattcc gaatggattg agtatcacgt caaaaaatgt gatgtcgtgt tgccgctggt
     3361 ggcgatagcc acgccgattg aatatacccg caacccgctg cgcgtatttg aactcgattt
     3421 cgaagagaat ctgcgcatta tccgctactg cgtgaagtac cgtaagcgaa tcatcttccc
     3481 gtcgacttca gaagtttatg ggatgtgtag cgataaatac ttcgatgagg atcattctaa
     3541 tttaatcgtc ggcccggtga ataaaccacg ctggatttat tcggtgtcta aacaattact
     3601 tgatcgggtg atctgggcct atggcgaaaa agaaggttta cagttcaccc tcttccgccc
     3661 gtttaactgg atggggccac gactggataa ccttaatgca gcgcgaattg gcagctcccg
     3721 cgctattacg caactcattc tcaatctggt agaaggttca ccgattaagc tgattgatgg
     3781 cggaaaacaa aaacgctgct ttactgatat tcgggatggt atcgaggcgt tataccgcat
     3841 tatcgaaaat gcgggaaatc gctgcgatgg cgaaattatc aacattggca atcctgagaa
     3901 cgaagcgagc attgaagaac tgggtgagat gctgctggcg agcttcgaaa aacatccgct
     3961 gcgccattac ttcccaccgt ttgcgggctt tcgtgttgtc gaaagtagca gctactatgg
     4021 caaaggatat caggacgtag agcatcgtaa accgagcatc cgcaatgccc gccgctgcct
     4081 ggactgggaa ccgaaaattg atatgcagga aaccatcgac gaaacgctgg atttcttcct
     4141 gcgcaccgtt gatcttacgg ataaaccatc atgaccaaag tcggcttacg cattgatgtc
     4201 gatacctttc gtggcacccg tgaaggcgtg ccgcgtctgc tggaaatctt gagtaagcat
     4261 aatattcagg ccagcatttt tttcagcgtc ggcccggaca atatgggccg ccatctctgg
     4321 cgactggtga agccacagtt tttgtggaag atgctgcgct caaacgcggc atcgctttat
     4381 ggctgggata ttttactggc aggtacggcc tggccaggta aagagattgg tcatgccaat
     4441 gccgatatca ttcgtgaagc ggctaaacat cacgaagtcg gcctgcacgc ctgggatcac
     4501 catgcctggc aagcccatag cggtaattgg gatcggcaaa caatgatcga cgatattgca
     4561 cgcggccttc gcaccctgga agagattatc ggtcaaccgg taacctgttc tgccgctgct
     4621 ggctggcgtg ctgaccaaca ggtgatcgaa gcaaaagaag cgttccattt gcgctacaac
     4681 agcgattgtc gtggggcgat gccgtttcgt ccattgctcg aatcaggaac ccccggcact
     4741 gcgcaaattc cggtgacctt acccacctgg gatgaagtga ttggtcggga tgtgaaagca
     4801 gaagatttta acggttggtt actcaaccgc atccagcgag ataaaggcac gccggtttat
     4861 accattcatg ccgaagttga aggctgcgct tatcagcata attttgtgga tctcctgaaa
     4921 cgcgcagctc aggaaggcgt gacattttgc cctttaagcg aactgttatc agggacgttg
     4981 ccgctcggac aagttgttcg cggaaatatt gccggacgtg aaggctggct gggttgccaa
     5041 caaatggcgg gtagtcactg atgaaatcgg tacgttacct tatcggcctc ttcgcattta
     5101 ttgcctgcta ttacctgtta ccgatcagca cgcgtctgct ctggcaacca gatgaaacgc
     5161 gttatgcgga aatcagtcgg gaaatgctgg catccggcga ctggattgtt ccccatctgt
     5221 tagggctacg ttatttcgaa aaacccattg ccggatactg gattaacagc attgggcaat
     5281 ggctatttgg cgcgaataac tttggtgtgc gggcaggcgt tatctttgcg accctgttaa
     5341 ctgccgcgct gatgacctgg tttactctgc gcttatggcg cgataaacgt ctggctttac
     5401 tcgccacagt aatttatctc tcattgttta ttgtctatgc catcggcact tatgccgtgc
     5461 tcgatccgtt tattgccttc tggctggtgg cgggaatgtg cagcttctgg ctggcaatgc
     5521 aggcacagac gtggaaaggc aaaagcgcag gatttttact gctgggaatc acctgcggca
     5581 tgggggtgat gaccaaaggt tttctcgccc ttgccgtgcc ggtattaagc gtgctgccat
     5641 gggtagcaac gcaaaaacgc tggaaagatc tctttattta cggctggctg gcggttatca
     5701 gttgcgtact gacggttctc ccctggggac tggcgatagc gcagcgggag cctgacttct
     5761 ggcactattt tttctgggtt gagcatattc aacgctttgc actggatgat gcccaacata
     5821 gagcgccgtt ctggtactac ttgccggtca tcattgccgg tagcctgccg tggctgggat
     5881 tactccccgg tgcactgtac gctggctgga aaaaccgcaa gcattccgca accgtttatt
     5941 tgttgagctg gacgataatg ccgctgctgt ttttctccgt cgctaaaggc aaattgccca
     6001 cctatattct ttcctgcttt gcacctctgg caatgctgat ggcgcattac gctttgctgg
     6061 cagcaaaaaa taatcctctg gcgttgcgga ttaatggctg gattaacatc gcttttggcg
     6121 tcactggcat tattgccaca tttgtggtct ccccctgggg accaatgaac acaccggtgt
     6181 ggcaaacctt cgagagctat aaagtctttt gtgcctggtc tattttttcg ctatgggcat
     6241 ttttcggctg gtacacctta acaaacgtcg aaaagacctg gccttttgcc gcgctttgcc
     6301 cgctggggct ggcgttgctg gtaggatttt caattcctga cagagtcatg gaaggaaaac
     6361 atccgcaatt ttttgtcgag atgacacaag aatcacttca gccaagccgc tatattctta
     6421 ctgatagcgt cggtgttgcc gcaggtctgg catggagcct gcaacgcgat gacatcatca
     6481 tgtatcgcca gacaggtgag ttgaaatatg gccttaatta tccggatgca aaagggagat
     6541 ttgtcagcgg tgatgagttc gcaaactggc ttaatcaaca tcgtcaggag gggattatta
     6601 cactcgtgct ttcggttgac cgcgatgaag atatcaatag tctcgccatt ccgcccgctg
     6661 atgccatcga tcgtcaggga cgtctggtac tcattcagta tcggcccaaa tgatctggct
     6721 aacattagtc tttgccagct tgcttagcgt tgccgggcag ttgtgtcaga aacaggcaac
     6781 ctgctttgcg gcggtaaaca aacggcgcaa acatatcgtg ctgtggctgg gactggcgct
     6841 ggcttgtctt ggccttgcca tggtgctctg gctgctggtc ttgcagaacg taccggtagg
     6901 cattgcctac ccgatgttaa gtctgaattt tgtctgggta acgctggctg cagtaaaact
     6961 gtggcacgag ccggtatcgc tgcgtcactg gtgtggggtg gcgttcatta ttggcggcat
     7021 tgtgatcctc gggagtacgg tgtaatgggc ctgatgtggg gattattcag cgtcattatc
     7081 gcctccgctg cgcaattaag cttgggtttt gcggcgagtc atctgccgcc aatgacgcac
     7141 ttatgggatt ttatcgcggc gctgttagct tttggcctgg atgcccggat attgttactc
     7201 gggctgctgg gttatctgct ttccgttttt tgttggtata aaacactaca taaacttgcg
     7261 ctaagcaaag cctatgcctt gctcagtatg agttatgtgc tggtatggat tgcttcaatg
     7321 gtacttcccg gctgggaagg gactttttcg ctgaaagcac tactgggagt agcctgtatt
     7381 atgagcgggt tgatgctgat tttcctgccc acaacaaaac aacgttactg agttttccct
     7441 gccgctttac actgccgttc ccactcatcg gggctataac agcttgcaga aagaactttc
     7501 accgtgtgca gcttttcacg attaatacag taaagcgcat tctgcaaagg cgagagtaaa
     7561 tcccccactt tcacggcgaa gtcactcttc acttcggcga tcatttttat cgcgccgcca
     7621 gcatcgcaga gcataagtac atgtctgtta ttttgtttat tgcagcacga ttttttgacc
     7681 agccattcca ttgcattatc ctgtttgata agagttttca catcaattta cagattaaca
     7741 gataaaccta ttatcaacgg caatggaatg gcaaaattgc gaagtgaaac taatgatttc
     7801 ttaatcctgg cgttgcaccc actcttttaa cgcctgacgt gaaattttaa taccgccgtt
     7861 tttcagctcc ggcggtaaag tcagccagcg caccggttgt tgaaaacggg ccagcttatc
     7921 tttcacccat tcgccaagat caacggtttg ctggtcatac tccaccaccg ctaccggtcg
     7981 atgaccaaac tccttgtcag caacgggaac gataaacacc tgcaaaaccg caggatgtgc
     8041 agcaataacg cgctcgactt cttctggctg aatgccttcg ccaccactga agaacagatt
     8101 gtctaaacgt ccgacaatgg tcagcttgcc attatgcatc tcaccgcgat cgcgcgtggc
     8161 gtaccagcct tcgtcattaa ccagtggaac ccgttgcccg ttacgccagt aaccttctgc
     8221 catgctggca gcccgcagcc acacttcgtc gtttacgatt ttcacttccc gacccggcag
     8281 cggcgaaccg acgtctgcca gaccgtcggc ttctttcgca cacaccgtgg aggcaaactc
     8341 ggtcagacca tagccgcaaa agcaccgaat cccctgctcg cgcgcctgtt ccgtcaactc
     8401 gaccgggata gccgcgccgc caagtaaaac cgctttcagg gaaacggaac tacggttaac
     8461 cagcaaacgc cagagttgtg ttggcaccag tgaagcgtgc gtacagcctg ccagcatttg
     8521 ctccaatggc tgtttatcac gtaccgtcat ccgcgcacca gcgtataacc agcgccacat
     8581 aattccctga ccggagacgt gaaacagcgg taaagagagc aaccagtcat cgtgatcgcc
     8641 aaacggaatc agcgataaca ccccttcggc gctggcaaga tgagcctgat aagtatgaac
     8701 agcggctttc ggcaagccag tggaaccaga ggttaacgtc attgagcaca gacgcgtcgg
     8761 ctgccacgcc acggcatgta cgccttcaac ctgctgaata tgcagcgacg ttaacgccgg
     8821 aaacgtgttt tccccttccg gcaccagcgc aaattgcagc gtaagattgg gcagcaattc
     8881 ctcaagcagc ggttgcggca gctgagggtt cacgggcaac acccgcgccc cgcattgcag
     8941 taacgccagc caggccagca gcgtttgcgg cgtattccac gcccgcaaca tcacgccgct
     9001 gcccgcaacc acaccctgcg ccgcaaagct ggaggctaat tcatcgacgc gagcacaaag
     9061 ctcgcgccag ttgagttgct cgtcattaag acgtaaggcg atggcttctc cccgcacttg
     9121 ccgccagtga cgccacggcc agtcagagaa gatcataaca gccgctccag tgcatcaacg
     9181 tccactaacg gcagtggact ccccggccag cgacgaacct gctgcacctg catcagatcc
     9241 agcgtgtcca gtcccggaat ggtgtctggc gttaaccagg cagcaatccg cgccagttgc
     9301 attagaccta agctcgactc aatggaagaa ctgatcaccg ccgtcagccc cagcgcatgc
     9361 gccgccttca cctgctcgcg tactttctcc aggctgcccg tgagcgtggg tttgataact
     9421 accgcgcgca cgccctcttc agctacaaag gcaaaatccg gctcgcgcaa gctttcatcc
     9481 caggcaatgg caatgccggt ttcacgggca aacgcacgcg aatcatcgcg ggttttgcac
     9541 ggctcttcga gaaatgcgat gcggtggcga taatccgggt taacgtattt ggcaaactgc
     9601 tggcctttca gcggtgtcca ggcgcgattc gcgtcaagac gcaaatgcag atccggaatt
     9661 gcctccagca acagattcac caccatgccg tcgcgcacgg cttcatacaa tcccactttg
     9721 accttcgcca ctttctcgcc aggcatatcg gcaagtttga ggatcagatc gtcaggatcg
     9781 ccattacaca gcggtgccgc acggtaattg gccgcctgcg ggagcgtatc tgccagctcc
     9841 gccaatgcac aacttacgcc aaaggcaacg gaaggcatct gcggtaattc gcaatcgcct
     9901 gccagccagt tatttaccca ggcaagcagc acactttgcg catcttccca ggtttcctga
     9961 ctgaagcccg gcagtgggga gatctccccc cacccttcgc gctcaccctc acgcaggcaa
    10021 acatacagcc cgtcgcgggt ttttaaccgc ctgtcgcgca gaaccacccc cgcgtccatg
    10081 gggatctgcc agcggtatac ctgcgcgcta cgcattacgg attccgttta aatttgctga
    10141 aatcaggctg acgtttctgg ttgaaagcat tgcgaccttc ctgaccttct tccgtcatgt
    10201 agaacagcat ggtagcgttg cccgccagct cctgcagccc cgcctgcccg tcacagtcgg
    10261 cgttcagcgc agctttcagg cagcgcagcg ccatcgggct gttttgcagc atttcacggc
    10321 accaacggac ggtttctttt tccagatccg ccagcggtac cacggtgttt acaaggccca
    10381 tatccagcgc ctgtttcgcg tcgtactgac ggcacaagaa ccagatttca cgcgcttttt
    10441 tctgtccgac gatgcgagcc atgtaggaag cgccccagcc gccgtcgaag gaaccgactt
    10501 tcgggccagt ctggccgaag atggcattat cagccgcgat agtcaggtcg cacatcatgt
    10561 gcagaacgtg accgccgccg atggagtagc cagccaccat cgcgacaacc ggtttcggac
    10621 aggtacggat ctgacgctgg aagtccagca cgttcaggtg atgtacgccg gaatcatctt
    10681 tatagccgcc gtaatcgcca cgcactttct ggtcaccacc ggagcagaac gctttatcgc
    10741 ctgcaccagt cagaatgatc acgccgatgt tgtcgtcata acgcgcatcc gccagcgcct
    10801 ggatcatctc ttttaccgtc agaggacgga aggcattgcg cacctgcgga cgattaatgg
    10861 tgatttttgc gataccgtcg gtggattttt cataacgaat gtcctcaaaa ccttcggagc
    10921 agtcgtgcca ttcaaccggt gcgtaaagca ttgcttcatc aggataaatc atattgtgtc
    10981 ctttagtcag aaacgcaaga tctgcgccag acttgcgatt acgccagcgg gattttcccg
    11041 gtgcgcgtta tgtccggcgc gaggaatgac atggcagtcg gcagccagtt ccgccgccag
    11101 agcgcggaat ttgctgtcac gttcaccaca taaataataa aacgcaaatg tgcgggcgct
    11161 aaggttagca cgtaaatcgg gctggacggc gagagaagtc gcctccagca tggcggcaag
    11221 ggttgcgcca ttattgttgc tgcgcagcgc caccagctcc cggcgttgat cgtcattgag
    11281 cgaggcaaaa acaggctgtt gataccaatc ggcaaatacc gccgttaacg gttctgtacg
    11341 aaaacgctgc gcccattggc gatcggaacg ctgacgttcc gcgcgttgtt cagcattttg
    11401 caacccagga tgcccgcctt cgacaacaac tccacaaagc cccgccagct cctggcaagc
    11461 cgccatcatc gccacccgtc cgccaagcga gtaccccacc agccagaagt taaggatgtt
    11521 gtaactaacc agcgttttac acagtaagtc ggtgacatca tcaaatccat cgacgctgat
    11581 cgtcgctgaa ccaccgtgac ctgggagatc aacatacaac cgcgagtagt cggcaaacgc
    11641 ctcgcccact tcttgccatt catggcaatc gccggaaaaa ccgtgcaaaa acaccagcca
    11701 gggtaaacct ggtttgccgt gttttgcctg cgcgtgcagg atcataaatg gcttacctgc
    11761 gccagaagtt gctggagcgt ttgcgcacca tcggtgtcgt taaccaccat ttcaatcacc
    11821 gtggtggtcg gcgtacgcca ggcatcgact agtgtcgttt caagttcctg ccagttttgc
    11881 ggacgatgat atttcagctc gaacatcgcg gcggcgtgct caaaatggac gttttgcggc
    11941 atcagataga aacgcccgcg ctcgcttttc ggcgttggca acagcgaaaa aatttgcccg
    12001 ccgttgttgt tcaccacaat taataccagc ggtgcggaaa cctggcgcaa taacgccagc
    12061 gcgttgagat cgtaaagtgc ggagagatcg cccacaatcg ccagcgtcgg tttgccgctt
    12121 gcccgctgaa cgccggcggc agtcgagagc agcccgtcga taccgctggc accacggttg
    12181 ctgtacaccg ggtaacctgc cggaagttgc gaaagcgcat caatcagacg caccaccagg
    12241 ctgttaccga caaacaattg tccctgttca ggcaaatagt cgctgatgcg atgcgccagt
    12301 tgcgcttcgc caaacgcatc gcgacgggca ataaccgcct gcattgcctg ttccgccagg
    12361 cgcgggattt caacgcacca gggctggcgt ttttctgccg gatgcagctc cagccagtcg
    12421 gcaatattgg caattaagcg acgtccgcga tggtgtgccg gatcaagtcg cccttcaatg
    12481 tcatcaacaa tccagtactc ttctggttca cagcttgcct gccattggag gagtcgtttc
    12541 cccgtcaggc tgcttcccaa ttgcaccact atttgtgcct gttgcagttc gctggtcgct
    12601 ttggcattgc ctaaccagag atcggcacac ggcagcggct gtccggtttg cgacagcacg
    12661 tcgccaatca gcggccagcc aagagtttgc gcccacagtg caactttttt gccctcttcc
    12721 gcactcatgc gcccggcaac caccacaccg cgcttttgtc gccagaagaa ccagtcgcgc
    12781 tgtttttcac tttcccgacg aggcgcttca cgcagccacg gtttgtcgtc ctgccaccag
    12841 tcgcccagcc gctgttgcca gctaatcccc gtgtcgtcca tttcgccata cagcggttca
    12901 gcaaacgggc agttgatatg gactccacca gcatgaagcg taccgagagc gtggtcgatg
    12961 gtagaaacca gccaacgtgc ggggatatcc tgggtcgggc gcggcagtga aatactgtgc
    13021 gtggggtgag aggcgaacat tcccggctga cgaatcgcct gattcgcgcc gcagtcaatc
    13081 agctccggcg ggcgatcggc ggttaacagg atcagttttt ctccggttaa cccagcttca
    13141 atcagcgccg gatagagatt tgctaccgcc gtgccggagg tcacaatcac cgccaccggc
    13201 tgcttgctga ctttcgccag ccccagcgcc agatgcccca gtccacgctc atcgaaatgg
    13261 gtgtggtgaa tgaatgcgga attctccgcc gccgctaacg ttaacggtgt agaacgcgag
    13321 ccaggggcga tacagatgtg tctgacgccg tgacgcgtta atgcttccag aatgaccgcc
    13381 gcccagcgtc ggttaaatgc gcttactgac atgagtttgt ccggtatcaa tattgcggct
    13441 aagtataagg agctacaaaa atagattatt gatatgaatc ggtaatgatg cgactcatta
    13501 ctattccatt tgtaataaag tacgcagccc tgccgctttg ttgtcgattt cctgccactc
    13561 ttgctcgggg tcggaaccac ggacaatgcc tgcgccagca tatagccgca cgatattgcc
    13621 gctgattttt gctgagcgca gggaaacgca gaattcactt tgctgtaatg aaagatagcc
    13681 cgcagaaccg gcgtaccatt ctcgagtgaa cggttcgtga cgggcgataa actgtcgcgc
    13741 cagatcgcgc ggtaagccag caactgctgc cgttggctgc aactgatgta aacagatcac
    13801 atcatccgct ttgttgagtg aagtccagat acagcggcga agatgctgta ctttacgtag
    13861 acgcagtacc tgcggcggta aaacatccag cgtccgggta tcggcctgca atcgttggca
    13921 gatatcttcc accaccaaca tgttctcgcg ctggttttta tcatccgcca tcagccactc
    13981 acctaactgc tgcgcctgct tatcatcagg atgatttgct accgttcccg ccagcgcttc
    14041 ggtacgcagc gctttgtcac gccgccgcca taaccgttcc ggtgaagaac caagaaaagc
    14101 attttcgcca tcaaaggcca tgtaaaaatg gtagcaattc agattgagcc gacgactggc
    14161 agccatcatc gctgccgcat tgaccggact tgcgaaatgc aggtcagttg cccgagcaag
    14221 cacaactttg tcgagctcgc cttcggcgat ggttttcgtt gccagttcga ttaatagcgt
    14281 ccagcccgtt ttgtccggcc agtgttgttc tcgcgtggtg gttaaatgta atccaggcag
    14341 gggcttgata ctcaccagtg tggcgataaa ttcttttgcc ttgattgcat cgtgctgaag
    14401 ggagctttcg ctgaatagcg tcaaccgcag cgtggcttta ccgccacaac gtcgccattc
    14461 caggcgtggt aaaagtaaat agccctgcga cgggtcaaac gcattcaacc cccagatgcg
    14521 taagtcggcg tgttccgggt gctggcgaag aaaacgttgt gcctggtcca acgacgtaaa
    14581 acgggtaatc gcacccagga cggcagcttc ttcatcacca ttacgttgtt gccagtagaa
    14641 ttgcggatac acctgctgac tggccagcca gctcaaggca tcaaaagcgt ctttgagagg
    14701 gaaaggaata tcgataaccc gaatgccggg tgtcgccgga atctcttgcg acaaatggcg
    14761 cagtagattt tccagcgccg tagtaagtga ttgcacgcgg acctctccct gttaaaagcc
    14821 tcacattata cggggtacga caaaaaaaat gcagtacccc ggtgtaggga ggttttaacg
    14881 gcgtgccagc aacagtccta gaaccagccc aacggccgca cccacaccaa ttccttgcca
    14941 gggtttttcg tggacgtagt catcagcacg ataaactgcc tgcttcgccc gatagtaata
    15001 actgtctgaa gcctggctaa cccgtttttt cacatcatcc agcgcttttt ctgcacgcgc
    15061 tttcagctca acatatttct gatcggcggg atcgccagag gagcggagca cctcttccag
    15121 tgtttcacta agcagcgtca ggtcgtcatc aatacgtgta tcaccaaact gattagacat
    15181 tctcgttctc catttgtgta aaacctgtca ctaactatag acaagggtta ttgattacgc
    15241 ctgaattacc tcgcgtgcca tcccaatgtg tgggatacca tcttcttcat aaatatcggt
    15301 cacagggatg aaaccaaatt gcccataaaa gttttgtaaa tgcgcctgcg cccccagata
    15361 aatcggcttc tccggccagc ggcgagtaca cgattccagc gccttactca tcaattgctg
    15421 accgattttt tcaccgcgta aggcttcgct gacaatcacc cgaccaatca caacgggttg
    15481 cagttcgtcg tcacttttca gaatcctcgc atacgccacc agtgtcccgt tatgccaacc
    15541 gagaatgtgg cgattttctc cctccagatc gtcaccatcg atatcctggt aaggacagtt
    15601 ttgttccact acaaataccg cacaacgcag ttgtaataag gcataaagct gagaaacgga
    15661 taaatcagaa tgatgcagat cttgccagtc gatcatggaa ggctcctttg tgctgtttgc
    15721 tttatactag ccggaatatt ttcagcagcg tgatgaactc atggaattaa tttttttagg
    15781 tacttcagcc ggtgtgccaa cccgtacgcg taatgtcacg gcaatattgc ttaacctgca
    15841 acatccgacc cagagcggac tttggttatt tgactgcggt gaaggcaccc agcatcagct
    15901 actgcatact gcctttaacc ctggaaaact ggacaagatt tttatcagtc accttcatgg
    15961 cgatcatctc tttggtttac ccggcttgct gtgcagtcgt tctatgtcag gcattatcca
    16021 acccttaacg atttatggtc cgcacggtat ccgtgaattt gtggagaccg cgctgcggat
    16081 tagcggctca tggaccgatt atccgctgga aattgtcgaa attagcactg gcgaaatttt
    16141 cgatgatggc ctgcgcaaag tgaccgctta tccgatggaa cacccactgg aatgttatgg
    16201 ttatcgtatt gaagaacatg ataaaccagg tgcattaaat gcccaggcat taaaagctgc
    16261 tggcgtgccg cctggcccgc tgtttcagga attaaaagcg ggcaaaacaa tcatgctgga
    16321 tgatggaagg cagattaatg gcgcagatta cttagccgct ccagtgccgg gtaaagcgct
    16381 cgctattttc ggcgataccg gcccctgcga tgccgcgctg gagcttgcta aaggcgtcga
    16441 cgtaatggtt cacgaagcga ctctggatat ggcgatggag gccaaagcca acagtcgcgg
    16501 ccatagttct acacgccagg cggcggcact agcccgtgag gctggagtcg gtaagctaat
    16561 cattacccac gtcagctcac gctatgatga caaaggttgt cagcacctgt tacgtgaatg
    16621 tcggtcaatt ttcccggcga ctgaactggc gaatgatttc gcggtgttta gcatttaagt
    16681 cgaaagcggt ggttagttag cagattaatt taacgatacc aacacattta tttgacattt
    16741 tttcatctgt ttgccggata cgtttgatgt cgatatcagg caaacagaat tatcattttt
    16801 agttttgtga attgtccaga tctttcgcca gtccaatcag gcgaataaat tccgctctgt
    16861 aaccctgtgg atcttcccct tttgccttct gagcccactg tttgatctgc tgccaggagg
    16921 tattgttcag gtattcagaa ccgcgtaact tttgcccata tgcagccact gctgcgcgaa
    16981 agcgcatatc ttctgaaggt gcctttattg cagatgccaa cgggaattca actaactgac
    17041 tttcttttcc ctgtggggat ttccaacgaa tctttaacca ggcaagttct tttgttttgt
    17101 ccgatttcgc tgatttgtta tccggggcat agcgtaactt atcaattgat gctttttgcc
    17161 ctttcagcgt taattcaaat aacaatgtta tatgtttacc tgcgccaata tcacccgcat
    17221 caacgttgtc gttattaaaa tcctctgcct taagttggcg cttttcataa cctatctgac
    17281 ggtattccgt tacccacgcg ggattaaact caatttgcgc tttgacatct tttgctacgg
    17341 taatcaacgt ctgccgcatt tcactgttca acactttctg cgcctctgag agggtatcaa
    17401 tgtagctata gttgccgtta ccaacatcgg caattctcac catcattgcc tcgttataat
    17461 tgctatcccc cacgccaagc gtcgacagag taacaccgga ctcacgctgt tttttgacca
    17521 ttgattcaat cgattttgga tcgtcaatgc caacgttaaa gtcaccgtca gtggccaata
    17581 aaatgcgatt gataccacct ttaataaacc ccttcgctgc ctgctgataa gccatctcca
    17641 gcccggcacc gccattggta ctgccttctg catccagcga atcaattgca gcattaattt
    17701 ccgccttgtg actaccggag atagaaggca acgcaatacg agagtcgcca gcgtaggtca
    17761 cgatggcaat gttatcctgc tcacgaagtt ctttgaccaa taatttcaac gaagactgga
    17821 taagtggcaa acgttcatca gaaatcattg aaccagacgt gtcgataaga aagaccagat
    17881 tagaagcggg taactcttca cttttgcgat ctttcgccag gatatcaact ttcagcaatg
    17941 ttcgctgttc attccagggt gcaggtgcca attcgtagcg catagcgaaa ggtattggct
    18001 tagaggccgg aatagattgt ttgtctttga tatcccagtc agacgggaaa taattgacta
    18061 tctcctccac ccgcacagcg tctggcggag gtaacagccc ttgattaagg aaacgccgca
    18121 cattcgcata actgccggta tcgacgtcaa ggctaaacgt cgccaacggg ttttgcgcta
    18181 cctgcttaac cggattatca tcgaactgct ggtagcgagc ggttgctgga tttgcgattt
    18241 gggaggctgc tttttctctg gctgcatgtt gatattttgg agccgcctgc aatcgcccca
    18301 gcaaagcctg tttgtctgaa tattgttgca cttcttgctg ggctaaggct ttcgcgtctg
    18361 cagcggcttt ggcggcgctt tgctcagcca cttttgttgc cgcttgttgc gcggcaagca
    18421 cttgctggtc agtgggtgta gtagattgtt gttgctgact tttcttatcc tcaggttccg
    18481 gcccacatcc tgacaaaatc aaactactta taagcaacat gattatattt ttatttcgca
    18541 tataaaatcc ttttaaataa actcagggcc ccgacataaa atacactctt tgtataatcc
    18601 tgctaatctt aataaaatac aatatcgaaa cccataacaa ataatgattc aacaacgcaa
    18661 cccattaata atttgcatat gaaaaaaata aattttgctt ttattatatt atttctattt
    18721 tcactccctc tgattatttt ttaccaaccc tgggtgaatg cattaccacc aacgccccga
    18781 cacgctagtc ctgagcaatt agaaaaaaca gttcgttatc ttacacaaac tgtgcatcca
    18841 cgtagcgccg acaatattga taatctgaat agatccgcag agtatataaa agaggtcttt
    18901 atcagtagcg gtgccagagt taccgcgcag gatatcccca ttacgggtgg cccctacaaa
    18961 aacattgttg ctaattatgg tcctgccgat ggaccgctga ttattattgg tgcgcactat
    19021 gactctgtca gtagttacga aaacgatcaa ttgacctata cgccgggcgc ggatgataac
    19081 gccagcggtg tggcaggatt actcgaactg gcacgtttgt tacagcagca agcaccgaaa
    19141 acaggcgtgc agctggtcgc ctatgcgtcg gaagaaccgc ccttctttcg tagcgatgaa
    19201 atggggagcg cggtacatgc agcttcgctt gagcgtccag tgaaattaat gatagcgctg
    19261 gagatgattg gttattacga ctctacgcct ggtagccagg attacccatc cccggccatg
    19321 tcctggcttt atcccgatcg gggagacttt attgccgtgg tcggcagaat gcaggatatc
    19381 aacgccgttc gtcaggtaaa agcggcattg ttgtcatccc gggatttatc tgtttattct
    19441 atgaatgccc caggttttat tcccggtatt gatttctctg atcaccttaa ttattggcaa
    19501 tacgatattc ccgccgtaat gattactgac accgcttttt atcgtaataa acaataccac
    19561 tttcccggtg atatcgcaga cagattaaat tatcagaaaa tggctcaggt agtggatgga
    19621 gttacaacct tgttatacaa cagtaaataa taaaaatttc tcgaggcgga tccagaaaaa
    19681 gcaacatgcg cattttattt tctttcgtct gttttaagat gcgaaacatg aaattcaacg
    19741 gaggaaaaat aaatgggaat gattggctat tttgcagaaa ttgactcaga aaagattaac
    19801 caactgcttg agtctactaa aaaacctttg atggataata tacatgacac gctttcagga
    19861 ttacgccgac tggatattga taaacgctgg gattttttac actttggcct gacgggtaca
    19921 tctgcatttg accccgcgaa gaatgacccg ctaagtcgcg cagtgcttgg tgaacacagc
    19981 ctagaagatg gcatagatgg cttcctggga ttgacctgga atcaggagtt agccgcgaca
    20041 atcgaccgac tggaatcact ggatcgaagt gagctgcgta aacagttttc cattaagcga
    20101 ctcaatgaaa tggagattta tccgggagta accttttcag aagagttaga ggggcaactc
    20161 tttgcttcga tcatgcttga tatggaaaag ctgattagcg cgtatcgacg tatgctgcga
    20221 caagggaatc atgcgctgac ggttattgtt gggtgatggt gtcagggcac ccaaaaaaac
    20281 cgccgaacat gtcggcggct ttctgactta caaactgact gcttacatca gcggcattgc
    20341 taaccgcaca atgctaatca gcggttgtgg ccatacaccc agcaccagta ccaacagtgc
    20401 agagatcagc accacgatac cgcctgcgct gtactgccag tttgatggtg catcgcgacc
    20461 cggttgttcc ggagcgtgaa ggtataagct caccgccaca cgcaggtagt agtagaggcc
    20521 gattgccgaa ccgacaacta cggcacccac cagccaccac aagtgtgcct ggacaccgac
    20581 cgccagcacg tagaacttac cgataaagcc cagcgtcatt gggataccag ccagtgaaag
    20641 catcatcacc gtcatcactg ccgcgaggat cggacgatgc cagaacagac cgcggtaaga
    20701 gaacagggaa tcagcatccg ggccacgata cgggctggac atcaggctga ccacgccgaa
    20761 cgcgccgagg ctgctgaaca gataacctgc caggtaaacc cctaccgctt ccatcgacat
    20821 ctcgccggtt tgcagcgcaa tcagcgccac cagcagatag ccgaggtgag agatagatga
    20881 gtaaccgagc agacgtttga tattggtctg gctcagcgcc atcaggttac cgaagatgat
    20941 ggaggcaaag gcgataatcg ccagcactac gcgaatcgct tcactgtcac ccaccggtgc
    21001 gtaaaggaac aaacgcatca ccacgccgaa gatagcgatt ttgctcgccg tcgccaggaa
    21061 agtggaaacc ggcgcaggcg cgccctggta tacgtctggc gtccacaggt ggaacggcac
    21121 cagagagagt ttgaagccga ggccaacaat catcaggccg aaacctgcca gcaacagcgg
    21181 ctcgttgagc ataccgtcgc cgaggttttt acccagtgcg acaaacgaca ggtcgccaga
    21241 ctgcgcatac accagcgcca taccgaacag caggaaagaa gacgctgcgg cagaaaggat
    21301 ggtgtatttg atactggctt ccagcgaacg tttctggcgg aaagcgtaac cgaccaggcc
    21361 aaacagcggc aaagagatca gttcgatacc gaggaacaga gacgccagat ggttggcatt
    21421 cgccagcagg atcccgccca gcgcggcaat taacaccaac aggtagaact catccttgtt
    21481 gtcgttatag ccttcaagcc acgggtaggc gaaagtacag gtggcgaggc tcgccaacaa
    21541 taccagcccg gtgtaaagca tggcgaaacc atcaacgcgc atcagtggcg taacgtccat
    21601 agcgcccgcc tggccgacaa accagagcga aaccagcgcc gcgttaagcc caataaccga
    21661 gagcgtagcg ttgagaaaat gattgcgtcg ccacgcaatg gagagcatca caaccaccac
    21721 cgtcaagccg acgatcagca acggtagcag tgcgatcagg ttttgtggag ttattgtcat
    21781 ggcgatttac ggccttgtag tagtaacgga attaacaaac cactgctgga tattgccaat
    21841 cgcggagtgc gaggtatcca gaatcggctg cggatagaag cccagcagta ccagcagcac
    21901 caccagcaac aggatcataa acagctcacg cagcgacatc cctggcagtt cctggctggc
    21961 aatctggctt ttcgctttac cgaaataagc gcgatgcagc atcgccagcg aataaacaga
    22021 tgcaaagacc agcccaaagg tagagataac ggtaattacc gggacaacct ggaagctacc
    22081 gaacagaatc ataaattcgc cgacgaagtt accggtgcca ggcatcccaa gcgttgccac
    22141 cgcaaagaac agcgacagtg ctggcagcca cttcatcttg ctccacagac cgcccatcat
    22201 gcgcatgtcg cgggtatgga tacgttcata gagctgaccg cagagaataa acagacccgc
    22261 cgctgacaag ccgtgtgcaa tcatctggat taccgcgccc tggtaggcca actggctacc
    22321 ggtgtagata gcaatcagca cgaagcccat gtgggaaacc gaggtgtagg cgatcagacg
    22381 tttgatatcg gtctgggcga aggccatcca cgcaccatag aagatgccga taacacccag
    22441 ccacatagcg attggcgcga actctgccga cgcgttcggg aacagcggta gggagaaacg
    22501 cagcagaccg taagcggcgg ttttcagcaa gatccccgcg aggtcaacgg aaccggcggt
    22561 cggagcctgg gagtgcgcat ccggcagcca gccatgcagc ggaaccaccg gcattttcac
    22621 tgcgaaggcg atgaagaagc ccagcatcaa caggtattcc acgccgttag acatcggcgt
    22681 attcagcagc tcttcatagt tgaaggtcca gacgccggtc gcattgtagt gaacgaaaac
    22741 cagcgcctgg atggcgatca acatcaccag accactcgcc tgggtgtaaa tgaagaactt
    22801 ggttgccgcc gtgatacgcg ttttaccgtc agaggcttta tgcccccaca gtgcgatcag
    22861 gaagtacatc ggcaccagca tcatttccca gaagaagaag aacaggaaca tgtcgatggc
    22921 aaggaacacg ccgataacgc cgcccaggat ccacatcagg ttgaggtgga agaagccctg
    22981 gtatttttcg atctctttcc acgaacagag taccgccagc acaccgagca gaccggtcag
    23041 cacgaccatc agcaacgaca gaccgtcaat ggcgagatgg atagagatac caaaacgcgg
    23101 gatccacggc atgtcgaatt cagactgcca ctgcggaatt ccggcggatt gcgtcagtga
    23161 ataaccgccc tgcaaccaca gttgcagcga cagcgccagc gtcaatccca tggttaccag
    23221 cgcgatccag cgcggcacct tgacgccaaa gcgttcggtc tgccagcaca ggaagccgcc
    23281 gataaaggga attaatatta gccagggtag taacatggcg atctttattc cttgtaaaag
    23341 tcccgtcagg accggatttt caacgaattc tcacgacaga aaattctctt cggactgggg
    23401 gtagtgtcgg atgcgccgcg aagacggctt atccgaccta cgttcttata tgcccagggg
    23461 caatcccaca atccttaact caacgcagta ccatcaacag agccagcacc acgaccgcac
    23521 cgatgctcat ggatgccaca taccagcgca gataaccgtt ctcgcttaac agcagacctt
    23581 tacctgcaaa gcgggaaagg acagccggga tgttcatcat tgagttcagc ggatcgcgtt
    23641 tcagcaacca ggcaataccc aggaacggct tgacgaacac tttgtcgtac agccagtcaa
    23701 agccccaggc gttgtaccac caggtaccca gcagacggcc cggcgcactg ttggcgatgg
    23761 aggtcaccag agtacgttta cccagccaca gccaggcagc cagcagaatg ccgaccaccg
    23821 cgaccacgcc agaggtaatt tccagggtca acatgctgcc gtgcgccagc tccgtcgttt
    23881 gcggaagcac gccctgcagc ggcggtacaa tcagtgcacc aacgaaggtg gaaaggatca
    23941 gcagcacaat cagcggcagg ctgtgagtta cccctttcac ggcgtgagcg tgaatttgtt
    24001 cttttccgtg gaagacgatg aaaatcatac ggaaggtgta gagcgaggtc ataaacgcac
    24061 cgaccagacc tgccaccatc agattgatat gtccattcgc catcgcaccc gcgaggatct
    24121 catccttact gaagaagccc gcagtgacca gcggcagtgc cgatagtgct gcgccgccca
    24181 ccaggaagca gagataaacc agcggaatag atttacgcag accacccatc ttaaagatgt
    24241 tctgttcgtg atggcaggcc agaatgacgg aaccggatgc caggaacagc agcgctttaa
    24301 agaacgcgtg ggtcatcaag tggaaaatcg ccgcatccca tgcctgcacg ccaagcgcga
    24361 ggaacatgta gccaatctgg ctcatggtag agtaagcgag aacacgtttg atgtcggtct
    24421 gtaccagcgc ggcaaaaccg gccagcagca gcgtaaccgc cccgacaata cccaccagat
    24481 gcagaacttc cggcgtcatc aggaacaggc cgtgggtacg ggcgatcagg tagacacccg
    24541 cggttaccat tgttgcggcg tggatcagcg cggagacagg cgtcgggccc gccatcgcgt
    24601 cggcaagcca tgtctgcaac ggcaactgcg cagatttacc gaccgcaccg cccagcagca
    24661 tcagcgtcgc ccacatcagc atgttattgc cgtcagcaaa gtgcgctggt gccagttcca
    24721 ccatttcgcg gaagttcagg gtgcccagtt cgttgtaaag aatgaacagc gcaaaagcga
    24781 ggaagacgtc acccacacgg gtcacgacga acgctttcat tgccgctgcg ccattcttcg
    24841 gatcggtgta atagaaaccg atcagcagat aggagcacag gcccacgcct tcccagccga
    24901 ggtacatcaa cagtaggtta tcggcgagaa ccagaactac catgctggcg atgaacaggt
    24961 tggtgtaagc gaagaagcga gagtagccct cttctccgcg catataccag gaggcataca
    25021 tgtgaataag gaaacccaca ccagtgacca ctgagagcat ggtcagcgac aggccgtcca
    25081 gcaccagatt gaaaccgatg ttaaagtcgc ctaccgacat ccacgtccac agcggctggc
    25141 tatatgcctg ctcaccgtta gcgaagaagt caacgccgat aaaggcggtt accagcgccg
    25201 ccaggcccac agagccaacg ccgacgatcg ccgagacgtt ttcagaccag cgcccacggg
    25261 agaacgccag caggacgaag ccaatcaatg gcaaaataat ggttaaggca agcatgttca
    25321 tccgcgcatc tcacttactg aatcgatgtt caggttctgg cgacgacggt gaagttgcag
    25381 cagcagcgca aggccgatac tcgcttccgc cgccgcgagg ctgatggcga gaatgtacat
    25441 cacctgaccg tcggtctggc cccagtagct tccggcgacc acaaaggcca gcgcggaggc
    25501 gttaatcatg atttccagac caatcagcat aaacagcaga ttgcgacgga taaccagacc
    25561 ggttaagcca agaacgaata agattgccgc gaggatcagt ccatgttgta aggggatcat
    25621 gcgtgctcct ccgtttttct tttcgcgctg tcgtctttac gattgctcag cacttcaccc
    25681 gcacgctctt cacgaccgac gtggaaggcc acaaccagac ccgcgagcag cagcatagaa
    25741 gccagttcca ccgccagtac gtaaggcccg aacagcgtaa tacccactgc tttagcactg
    25801 attggcgtac cgtcgatacc ttgatcgtta acaccgagaa tggcgtaaac aatcaccacc
    25861 agcatgatgg ctgacaaaat tgccggacca atccacacct gcggtttcaa ccactggcgt
    25921 tcctgttcga tttctgaacc gcccaggttg agcatcatca ccacgaacac gaacagcacc
    25981 ataatggcac ccgcatagac gataatttcc agcgcaccgg caaagtaagc gcccagtgag
    26041 aagaacaccc cagagatcgc cagcagcgaa ataatcaggt acagcagcgc gtgtaccgga
    26101 ttggtatggg tgatcactcg caaggtcgca agtatggcta tcaggccaca gatataaaaa
    26161 gcgaactcca ttgcccctct ccttacggta acaggctctt gacgtcgata ggcttggctt
    26221 cgttctctgc ttcgccctta tctttgccgt cgattgccat acctgccatc cggtagaagt
    26281 tatattccgg gtatttgccc ggaccggaga tcagcagatc ctctttctcg taaaccagat
    26341 cctggcgctt gtattccccc atttcgaaat ccggggttaa ctgaatcgcc gtggtcggac
    26401 aggcttcttc gcacagacca cagaaaatgc agcgtgagaa gttgatgcgg aaaaattccg
    26461 gataccagcg accgtctttg gtttctgctt tttgcagcga gatacagccg accgggcagg
    26521 ctaccgcgca gaggttacag gctacgcaac gctcttcgcc gtccggatcg cgggtcagaa
    26581 cgatacgacc acgataacgg ggcggcagat agaccggctc ttccgggtac attcgcgttt
    26641 cgcgtttggc gaacgcgtgc aggccgatca tccagatact acgaacctgg gtgccgaaac
    26701 ctactaacaa ttcttttaag gtcatggtct tattgcccct tattgcgcct gccagagaat
    26761 gacagccgcc gttaccagca agttgatcag cgtcagcggc aggcagattt tccagccgaa
    26821 ggacattacc tggtcataac gcggacgcgg taacgacgca cgaatcaaaa tgaacatcat
    26881 cataaagaac gcggttttca gcgcgaacca gatgaatggc ggtaacaacg ggccttgcca
    26941 gccaccgaag aacagcgtca ccatcagtgc agagatggtc acaatcccga tgtattcgcc
    27001 cacgaagaac agaccgaact tcataccgga atattcaatg tggtaaccat ccgccagttc
    27061 ctgctcggct tccggctggt caaacgggtg acggtgacac accgccacgc ccgcgatggc
    27121 aaaggtaata aaaccaaaga attgcgggat gacgttccac acatgcgcct ggctgttgac
    27181 gatgtcggtc atgttgaatg aaccggcctg cgccaccacg cccatcaagg aaagcccgag
    27241 gaacacttcg tagctcaggg tctgcgcaga agcacgcatc gcacccagca gcgagtattt
    27301 gttgttactt gaccagcccg caaacagcac cgcgtaaacc gccagacctg ccatcatcag
    27361 gaagaacaaa atcccgatgt tcaggtcggc aaccacccaa cccggactga ctggcacaat
    27421 tgcaaaggcc agcagcagcg aggtaaaggc aatcatcggt gccagggtaa agatgacgcg
    27481 atccgagaat ttcgggatcc agtcttcttt aaagaacatt ttgatcatgt ccgcaaccag
    27541 ctggagcgaa ccgccccagc caacacggtt aggtccataa cggttctgga acagacccag
    27601 caggcgacgt tcgccaaagc tcatgaatgc cccacaggtg actaccacca gcaggatcac
    27661 caccgcttta aggacggtca gcaggatctc aatcagttcc ggtgatatcc aactcattgt
    27721 tgtgcctcct tgagatcctc aagatgcgcg ccagccagca ccggagcaat gccggacata
    27781 cccatcggta agcccacctg ccctgccgtc agcccttcgg cgatttcaac cggcagcgtg
    27841 accgtgttgc catcgtaact aaaggagacg cgtgtacctg cgttcacccc caacttcgcg
    27901 gcatccgctg ggttgagttt gatgtacggc tgcggcatac ggctctggaa gaccggagca
    27961 cgctgtgaca attcatcgct gccaaacagg tggtagtacg gcgcgatacg ccatttcccg
    28021 tcctgcggct ggaagcgtgc cggtacgctg gtgaagtaat ccagaccgtt ttcgctggtt
    28081 tcaaacagac gcacgcccgg atcgccaaaa cgcagtttgc cgcccacttc gtcctggaat
    28141 ttgttccacg cctgcgggga gttccagcct ggtgcccagg caaacggcac ttgcgaacgg
    28201 tgcgcggtcg gctggttgtt accttccatc gagaaggtga acatagtgtc aatatcctgc
    28261 ggctgacgcg gctcatgaac gctgatattg gcgcgcatgg cggtacgacc gctatagcga
    28321 tgcggttcac gggccagttt ctgcccacga atacggaatg tcgcatccgg cgcagcatct
    28381 ttgatacctg ccagttccgg gattttcgcc acaacagcgt caatcacgtg gtcgagctgc
    28441 gtccagtcca cttcacggct cagcagggtg ctatgcagcg agtgcagcca gcgccagctt
    28501 tccagcatga cagttttgct gtcgtaataa gccggatcgt aaacctggaa gaaacgttgg
    28561 gcgcggcctt cgttgttgat caccgtaccg tcgctttcag caaagctggc ggcggaaagt
    28621 accagatggg cgttttccat aatcgctgtg cgttgatggt caaccaccat caccagcggc
    28681 gctttagcca gcgcagcatt cacgcgggta gcggaagcgt gacgatgcag atcgttttcc
    28741 agcaccacca ccgcgtcggc gcgtccggtt tccagttcgg ttaacgcttc ttcaagcgat
    28801 ccaccgccca taatgcccag ccccatgctg ttgacggaac gggcaatcat ggtgataccg
    28861 acgtcagcgc cgcgaccttt cagggctttc gccacgttag ccgcagcctg aatcacttca
    28921 gcgctaccag cgttcgtccc ggagataatc aacggtttct tcgcaccagc cagtgcctgc
    28981 acgatgacgt cgattttgct ttgcagctca ggctcaatac cgtcaaccgc tggtgcagag
    29041 ttatccagcg catgagcgat ggcaaaacct aaacgcgcct gatcttcaac cggtgcgcgg
    29101 taagtccacg ccgcgatatc atccagacgg gtgtcatcaa cgttggtaac aaacagcgga
    29161 tgcttcgcac gttgaccgat gttgaggatt gccgcaatct gccagtcagc cactttctgt
    29221 gctgccgcca tttcgcgcgc tttacctttc accgcctgac gcactgccag cgcgacgcgc
    29281 gcgccggtct gggtaacgtc ttcgcccagc accagtaccg catcgtaaga ttcgatttcg
    29341 cgcagagccg gagtataaat gccgccttca cgcagtactt tcagcgccag ttgcagacgt
    29401 tcctgctcac cgtgagcgat accggtatag aagttttctt cgcccaccag ctcacgcagc
    29461 gcaaagttgc tttccacgct ggcacgcgga gaaccaatac cgatcacttt cttcgactga
    29521 cgcagaatat ctgctgcgcc ctgcattgcc tgttcggcgt tgagggtaat gaaatcatcg
    29581 ccacgacgct gtactggctg acgcggacga tctttcaggt tgacgtaacc gtaaccgaaa
    29641 cgaccacggt cgcagaggaa gtagtggttt accgtaccgt tgtaacggtt ttcgatacga
    29701 cgcagttcgc cataacgctc gccggggctg atgttacagc cgatggaaca ttgctggcag
    29761 atgctcggcg caaactgcat atcccattta cggttgtaac gctcggagtg cgttttgtcg
    29821 gtgaatacgc cggtcggaca aatttcgacc aggttaccgg aaaattcgct ttccagcgtg
    29881 ccgtcttccg ggcgaccgaa gtagacgttg tcgtgcgcac cgtaaacgcc caggtccgta
    29941 ccgtcagcgt aatctttgta gtaacgcacg cagcggtagc aggcgatgca gcggttcatt
    30001 tcgtgagaga tgaacggccc caaatcctga ttacggtgag tacgtttggt gaaacggtag
    30061 cgacggaagc tgtgtccggt catcacggtc atatcctgaa ggtggcagtt accgccctct
    30121 tcacataccg gacagtcgtg cgggtggttg gtcatcaacc actcgaccac gctttcacgg
    30181 aactgtttcg cttcttcgtc gtcaatggaa ataaaggtgc catcggaagc cggtgtcata
    30241 caggacatca ccaggcgacc acgcgtgtct tccgcgtttt ggtattgctt caccgcacac
    30301 tggcggcaag caccgacgct tcccagcgcc ggatgccagc aaaagtaagg aatatcaagg
    30361 cccagagaca gacaagcttc cagcaggttg tccgccccgt tgacctcgta ttctttgccg
    30421 tctacatgaa ttgtagccat tagcatgctt ccagttttct cagtcagaga ctgagcgtta
    30481 atcgaaattc ggttaccagc gctctttcag caggttcggc tgaatcccat taatcaaatg
    30541 ggtattgctg aacggctgtt tgattcccgc ctcaaattct tcgcggaaat atttgatggc
    30601 gctctgtaac ggctccactg caccaggtgc gtgggcacag aaagttttac ccggacctaa
    30661 gaatcgacac agttgctcaa gtgtttcgat atcgcccggc tgaccttcac cacgctccag
    30721 cgcacgcaga attttcacgc tccacggcag accgtcgcgg catggcgtac accagccgca
    30781 ggactcacgg gcgaaaaact cttccaggtt acgcaccagc gacaccatgt taatctcgtg
    30841 gtcaaccgcc atcgccagcg ccgtacccag acggcttccc gctttaccga tactttcgaa
    30901 ttccatcggc aggtcaaggt gcgcttcggt caggaagtcg gtgcccgcgc cgcctggctg
    30961 ccaggctttg aatttcaggc cgtcacgcat accaccagcg taatcttcaa ggatttcacg
    31021 cgcggtggtg ccgaacggca gttcccacag acccggattt ttcacccgac cggagaagcc
    31081 catcagcttg gtgccagcat ctttactttt cgagatgttc tgataccact ccacgccgtt
    31141 agcgaggatc gccggaacgt tacacagggt ttcgacgttg ttaacgcagg ttggtttacc
    31201 ccatgcaccg gaggttgccg ggaagggcgg cttcgagcgt gggttagcgc gacgcccttc
    31261 cagggagttg attaacgctg tttcttcacc gcagatgtag cgccctgccc cggtatggac
    31321 gaacagttcg aaatcgaaac ctgttcccat aatgtttttg ccaagcagac ccgcttcggt
    31381 ggcttcggca atggcacggc gcagattcac tgccgcttca atatattcgc cacgcaagaa
    31441 gatgtagcca cgatacgctt tcagcgcaaa cgcagaaatg agcatacctt ccaccagcag
    31501 gtgcggtagt tgctccatca gcagacggtc tttataggtg cccggctcca tttcatcggc
    31561 attacacagc aggtaacgga tgttcatgga ttcgtctttc ggcatcaggc tccacttcag
    31621 gccagtagaa aagcccgcgc cgccgcgccc tttcagacca gagtctttta cctgattaac
    31681 gatttcgtcc ggagacagcc cggtcagcgc cttacgcgcg ccttcgtaac cgtttttgct
    31741 gcgatattcg tccagccaca ctggctgttt gtcatcgcgc agacgccagg tcagcggatg
    31801 cgtttcggga gtacggataa tgtttttcat ttataccgct ccagcagttc agggatcgct
    31861 tccggggtca gatgcgcgtg agtgtcctca tcgatcatca tgtttggccc tttatcacag
    31921 ttccccaggc agcaagttgg cagcagcgta aagcgaccgt caaatgtcgt ttgccctggt
    31981 ttgatgttca gttttttctc cagcgccgcc tgaataccct ggtaaccgtt gatatgacag
    32041 accacgctgt cgcaataacg gatcacatgg cggcctactg gctgacggaa gatctggcta
    32101 taaaacgttg ccacgccttc gacgtcgctc gccggaatac ccagcacatc ggcgatcgcg
    32161 tggatcgcgc catccggcac ccagccacgc tgcttctgaa cgattttcag cgcttcaatg
    32221 gacgccgcac gcgggtcttc gtagtggtgc atctcgtgct caatcgcttc acgctctgcc
    32281 gcactcagct caaaagcctc ggtttgtggt tgttgattct cgtgcataat tagcggtcca
    32341 catctgacat aacaaaatcg atactgccca gataaacaat caggtcagac accaggctgc
    32401 cgcggatcgc cgccggaatt tgctgcaaat gcgcataact cggcgtacgg atacgggtgc
    32461 gataactcat ggtgctgccg tcgctggtca ggtagtaact gttgatcccc ttggtcgcct
    32521 caaccatctg gaaggattca ttggcaggca tcaccggacc ccacgacact tgcaggaagt
    32581 gggtgatcag ggtttcgata tgttgcagcg tgcgctcttt cggcggcggc gtggtcagcg
    32641 gatgatccgc cttgaacggg ccttccggca tgttgttgag gcactgctca agaatgcgca
    32701 gactctggcg cagctcttcc actttcagca ttacgcgggt gtagcagtca gaaacaccac
    32761 cacccaccgg gatttcaaag tcgaagtttt catagccaga ataaggacgc gccttacgca
    32821 cgtcgaagtc gatcccggta gcacgcaggc ccgcgccagt ggtgccccac tccagcgcct
    32881 ctttcgcgcc ataggcggca acgccctggg aacgaccttt cagaatggtg ttttgcagcg
    32941 ccgctttctc gtaagacgcc agacgtttag gcatccagtc gaggaactca cgcagcaggc
    33001 gatcccagcc gcgcggcagg tcgtgcgcta cgccgccaat acggaaccac gccgggtgca
    33061 tacgaaaacc agtgattgct tccaccagat cgtaaatttt ctgacgatcg gtaaaggcga
    33121 agaacactgg cgtcatcgcg ccgacgtcct gaataaaggt ggagatatac agcaggtgac
    33181 tgttgatgcg gaacagttcg gagagcatta cgcgaatgac gttaacgcga tccggcacgg
    33241 tgatcccagc cagtttctct accgccagca cataaggcat ttcgttaacg cagccgccga
    33301 ggtattcgat acggtcggta tacggaatgt agctgtgcca ggactggcgt tcgcccattt
    33361 tctcagcgcc acggtggtgg taaccgatgt ctggtacgca gtcgacaatc tcttcgccat
    33421 caagctgcaa aacgatacgg aaagcaccgt gcgcagacgg gtggttcgga ccgaggttga
    33481 ggaacatgaa gtcctcgttt tcggtgccgc gcttcatccc ccactcttcc ggtttgaagg
    33541 tcagggcttc catctccaga tcctgtttgg ctttggtcag ctcaaacggc gagaattcgg
    33601 tagcgcgcgc cgggtaatct ttacgcagcg ggtgaccttt ccaggtttgc ggcatcatga
    33661 tgcggcgcag gttcgggtga ccgtcgaatg taatgccaaa tagatcccag gtttcacgct
    33721 cataccagtt agcgttcggg aatagtttgg taaaggtcgg tacgtgcagg tcgttttctg
    33781 ccagcgccac cttcagcatg atgtcgcggt tacgatcgat agaaatcaga tggtagaaaa
    33841 cggaaaaatc cgcggcaggt aacccttcgc ggtgtgtgcg cagacgttcg tccatgccgt
    33901 gtaagtcaaa cagcatgacg taaggtttcg gcagtttctt taagaaatcg cccacttcca
    33961 gtaattgttc acgcttgatc cacacaacgg gaaccccggt gcgagtcgcc tgaacagtaa
    34021 aggcatccgg cccaaaacgg ttgcgcagtt cgccaatcac cggatcatca agatgatcgc
    34081 gggtctgcca ggcgggttct tgcgcggtta agtcggtcat attgttcacc attgcaaatg
    34141 gtccgtggtg actgtcggcg cagtaagctt cgcgaaatag atttaggaat aagcgaagaa
    34201 aattcccttt gccgacaggc gcaaattaaa tctcgtcagg tgtacgcagg ttggttacgg
    34261 caatgcgttc accgcgcttg cgttcgcgct ctgattgcat attggcgcga taaacgccct
    34321 gatcgccaac cacccaggag agcggacgac gttctttacc gatagattcc tgcaacagca
    34381 tcagtgcctg catgtacgct tcaggacgcg gcggacagcc cgggatatac acatcaaccg
    34441 ggatgaattt atcaacgccc tgcacaacgg aataaatatc gtacataccg ccggagttgg
    34501 cacaggcacc cattgagata acccattttg gttccagcat ctggtcatac aaacgctgaa
    34561 taaccggtgc cattttggta aagcaggttc ctgcaaccac catcaggtca gcctgacgcg
    34621 gcgaagcacg caatacttca gcgccaaaac gcgccacgtc atgcaccgcg gtaaacgaag
    34681 tcaccatctc aacgtaacag caggaaaggc cgaagttata cggccaaatt gagtttttac
    34741 gaccccagtt aaccatgtca ttgagcttgc ccataaacac gtttttgtta acttcttgct
    34801 ccagagggtc ggttacgatc tcctgctttt gcagggggta acggtcgttc tcaccgttgg
    34861 gatctatgcg ggtgagcgta taatccatct taatgcctcg cggttagcgt tgacgattag
    34921 cgatactgtc cgtttccggg ttcatacgct cgcggcgtga acgcgcgggc gtccagtcca
    34981 gcgcgccaat acgcaccaga taaaccagac ctgccagtaa cacaaaaata aaaattgcag
    35041 cttccacaaa gcctacccag ccgctttcgc ggatagaggt tgaccatgcg aacagataca
    35101 gcgcttcaac gtcgaagata acgaagaaca tggccaccag ataaaacttg gcggacaggc
    35161 gtaagcgggc ggagccgacc gagtcgatac cggattcaaa cggaacgttt tttgacctcg
    35221 cgcgtgcgcg accgcctaaa aaccaaccgc ctaccagcat caggcaacac aggccaatgg
    35281 caacgataag aaagatagcg aatgcccagt gatgagcgat gacttcagtg gatgttgaca
    35341 tactcattgc ttactcatca aaagtagcgc cagattcact gctcttcacg gcagatggac
    35401 gccacatcga ttcatgggga ggaataaaaa aaaccttaca ataactgcag aaactatttt
    35461 atacagctaa ttgatgtggt cttttactcc tttctataac cttttgtcaa ctttaacaaa
    35521 ggtttcttca cactgattta cacaatgaca acaacatttg catttggcgc cctttctccc
    35581 cagatcattg acgactccag gaaaattaga tgttgttgaa tcgtgtccgt tgtgaagcaa
    35641 tggaaaaaat acgggtctat tttgacagga atttgtgtcg attcctcccc ccaaaagaga
    35701 gtattttctt gatctgtgac acgcttttgt cattctataa caaaaacgca gcaacaaatt
    35761 cacgtatttt ttaacattat tgtagcagga gatttttttc aggtgattat ttgtgcgtac
    35821 ggggcgtgaa tctctggtga ttgaaaaatg aacagtttta tacgttctgc acgatacgag
    35881 gaaggctttt tactaaaaaa aagccgctgg ggtttaaaat aaacccagcg gttcgttttt
    35941 acactattgt ctcaggaatt atctatcgtc cgtcgattac tcgatatccc tttcaatcaa
    36001 caatgagtca tctccttccg gagcagacat tgggctgtat tgccacggat tatggtagct
    36061 ctccatcgtc tgatagatca cctgggccag ctcattatta ctggacgggt catagcacag
    36121 caaatattcg gtatcaggta gcggcggtaa gccatctact ccactcagca cacgcaggtc
    36181 cggactcatc atctcgaccg gccttgccgt cacgccaaga ccggctttca ctgccgcacg
    36241 aacggccgga agcgtcgagg cgacataagc cagtcgccag ggaatatctg ctttattaag
    36301 cgtcgccagc accatatcgc gaaacggact tggatcatcc agcaacacaa gagggatcgg
    36361 ctcacctttt tgcaatacgt attccgctgc gcagtaccag tgtgttggcg aggtacgcag
    36421 gttcaatgcc ttaaaggtag aaggacgatg ggtggttacc atcaaatcca cttcctggga
    36481 ttccagcatt tctgccatgt aggcattacg tttaacgcgg acatccagcg ctagtttcgg
    36541 ataaaccgaa ctcacgcgat ttaacaggaa aggtaagatc gtatcggcag attcatctga
    36601 agcaccgata gttaacacgc cctgaagatt actgaacatt aatgatgagc aggcctcatc
    36661 attaaaacgc aggattttcc tggcgtaacc aagaagttga atgccatgtt cagttaacag
    36721 tttgttgcga ccgtgacgag cgaacagttc tttcccaacg agttgttcca gacgctgcat
    36781 ttgctgactt acggcggact gagtacgaca cacagcggca gctgcggcag caaaagtgtt
    36841 cagatcggca acagcaacaa atgttctcag cagatcgagg tcgaggttaa ttatcggacg
    36901 atttgcactt atcatatatt atcacttact ggcggctcat actgagctgg ttaatgctgt
    36961 gcacacacaa acaagcaatt ccatttgtaa tgtgcctccc tggcagtttc atccggaacc
    37021 cggacgaaag taaaaatgca tatgagttgc actaaaaaag cgactcacat tgttccgtta
    37081 taatgcctga agtagatcac agaatatatc ttcagggatc gcatatctat taagttactc
    37141 actcttttct atttatgaca tgcgcgtgtt tgtataaatg taaatgtgag tccttgttcc
    37201 actctcgtac agcatcgctg gtcatacgcg aacacgtaca aacagcaatg gtgaggcggc
    37261 atcaagagca gggatccgtc atttatgcaa gcattttacc ccaaaaacct tttatttata
    37321 agggtcattg cgaattatct gatgcaaagt tatgttatgt taggcaaag
//
LOCUS       DAPOXO010000047        36416 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPOXO010000047 DAPOXO010000000
VERSION     DAPOXO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36416
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.047"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            252..1637
                     /gene="dcuC"
                     /locus_tag="ROH59_002764"
     CDS             252..1637
                     /gene="dcuC"
                     /locus_tag="ROH59_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HDX4805223.1"
                     /translation="MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFIRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
     gene            complement(1678..2358)
                     /gene="dpiA"
                     /locus_tag="ROH59_002765"
                     /gene_synonym="citB"
     CDS             complement(1678..2358)
                     /gene="dpiA"
                     /locus_tag="ROH59_002765"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HDX4805224.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(2327..3985)
                     /gene="dpiB"
                     /locus_tag="ROH59_002766"
     CDS             complement(2327..3985)
                     /gene="dpiB"
                     /locus_tag="ROH59_002766"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HDX4805225.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSIISAVKTRDYKRLATIADKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKPGALEKGESYFITGKGSIGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMVIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELYLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
     gene            4365..5423
                     /gene="citC"
                     /locus_tag="ROH59_002767"
     CDS             4365..5423
                     /gene="citC"
                     /locus_tag="ROH59_002767"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HDX4805226.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            5438..5734
                     /gene="citD"
                     /locus_tag="ROH59_002768"
     CDS             5438..5734
                     /gene="citD"
                     /locus_tag="ROH59_002768"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HDX4805227.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            5731..6639
                     /gene="citE"
                     /locus_tag="ROH59_002769"
     CDS             5731..6639
                     /gene="citE"
                     /locus_tag="ROH59_002769"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HDX4805228.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            6650..8182
                     /gene="citF"
                     /locus_tag="ROH59_002770"
     CDS             6650..8182
                     /gene="citF"
                     /locus_tag="ROH59_002770"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HDX4805229.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCADLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYSGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSQAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            8186..8737
                     /gene="citX"
                     /locus_tag="ROH59_002771"
     CDS             8186..8737
                     /gene="citX"
                     /locus_tag="ROH59_002771"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HDX4805230.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHAWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHSHPLGRLWDIDVLTPEGDILSRRDYSLPPRRCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            8712..9590
                     /gene="citG"
                     /locus_tag="ROH59_002772"
     CDS             8712..9590
                     /gene="citG"
                     /locus_tag="ROH59_002772"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HDX4805231.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLNGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSRLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLL
                     LMATNGDTNVASRGGEGGLRWLQREAQTLLNNGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
     gene            9641..11104
                     /gene="citT"
                     /locus_tag="ROH59_002773"
     CDS             9641..11104
                     /gene="citT"
                     /locus_tag="ROH59_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HDX4805232.1"
                     /translation="MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDE
                     LKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFANTMSTHLEGFSPNATVIVLVLVFYFAH
                     YLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIY
                     GCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
     gene            11218..12024
                     /gene="rna"
                     /locus_tag="ROH59_002774"
     CDS             11218..12024
                     /gene="rna"
                     /locus_tag="ROH59_002774"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HDX4805233.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANAVALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY"
     gene            12254..12664
                     /gene="rnk"
                     /locus_tag="ROH59_002775"
     CDS             12254..12664
                     /gene="rnk"
                     /locus_tag="ROH59_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HDX4805234.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            13020..13448
                     /gene="uspG"
                     /locus_tag="ROH59_002776"
     CDS             13020..13448
                     /gene="uspG"
                     /locus_tag="ROH59_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HDX4805235.1"
                     /translation="MYKTIIMPVDVFEMELSDKAIRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAK
                     ELDADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            complement(13569..15134)
                     /gene="ahpF"
                     /locus_tag="ROH59_002777"
     CDS             complement(13569..15134)
                     /gene="ahpF"
                     /locus_tag="ROH59_002777"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDX4805236.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(15305..15868)
                     /gene="ahpC"
                     /locus_tag="ROH59_002778"
     CDS             complement(15305..15868)
                     /gene="ahpC"
                     /locus_tag="ROH59_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HDX4805237.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            16240..16986
                     /gene="dsbG"
                     /locus_tag="ROH59_002779"
     CDS             16240..16986
                     /gene="dsbG"
                     /locus_tag="ROH59_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HDX4805238.1"
                     /translation="MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQQYEASGGKLKLSVPANVSTEQMKVLSDNEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMRNK"
     gene            17191..18093
                     /locus_tag="ROH59_002780"
     CDS             17191..18093
                     /locus_tag="ROH59_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4805239.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLRGLEQTINIVNKSELKKNFII
                     YGPQLISCTNNNMLIRCLRQDTSIDIECHDILLSAENAEELLVQRKTDLAITLQPVIS
                     RSVICMPLHTIRNSLICSNKHPRITDTSNYEQIIAEEFTLLISKSAGIDEIQMDIDER
                     FINRKVSFRSSSLLTIINSISVTDLLGIVPTELYDLHRDFLKLKEIKLEQPLPAVKLY
                     ISYNKASLNNLVFSRFIDRLNDSF"
     gene            18240..19460
                     /locus_tag="ROH59_002781"
     CDS             18240..19460
                     /locus_tag="ROH59_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDX4805240.1"
                     /translation="MSIYKIPLPLNILEAAKERITWTLNTLPRICVSFSGGKDSGLML
                     HLTAEIARQMGKKICVLFIDWEAQFSCTINYVQSLREFYADVIEEFYWVALPLTTQNS
                     LSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFSFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQQLCNPLYNIMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKSITVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKAKNYQRYNERI
                     KGKRKEWGILCNND"
     gene            19433..20062
                     /locus_tag="ROH59_002782"
     CDS             19433..20062
                     /locus_tag="ROH59_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDX4805241.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRINAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLKKSIEIDGFTQPIVVTHTDKNALEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQFSRAWTVK"
     gene            complement(20063..21223)
                     /gene="ybdL"
                     /locus_tag="ROH59_002783"
     CDS             complement(20063..21223)
                     /gene="ybdL"
                     /locus_tag="ROH59_002783"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HDX4805242.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTKMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAYHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDVDSNITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRIALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATVWQQTDFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTMDD
                     VEFCQWLTREHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            21332..22420
                     /gene="hcxA"
                     /locus_tag="ROH59_002784"
     CDS             21332..22420
                     /gene="hcxA"
                     /locus_tag="ROH59_002784"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HDX4805243.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGER
                     AIAAAQTKLPPAFELPGVKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQEYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALA
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQVEIDKMIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVESFKA"
     gene            complement(22430..22627)
                     /locus_tag="ROH59_002785"
     CDS             complement(22430..22627)
                     /locus_tag="ROH59_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDX4805244.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(22740..24845)
                     /gene="cstA"
                     /locus_tag="ROH59_002786"
     CDS             complement(22740..24845)
                     /gene="cstA"
                     /locus_tag="ROH59_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HDX4805245.1"
                     /translation="MNKSGKYLVWTVLAVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFAITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGEVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKEPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(25026..25439)
                     /gene="entH"
                     /locus_tag="ROH59_002787"
     CDS             complement(25026..25439)
                     /gene="entH"
                     /locus_tag="ROH59_002787"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HDX4805246.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(25442..26188)
                     /gene="entA"
                     /locus_tag="ROH59_002788"
     CDS             complement(25442..26188)
                     /gene="entA"
                     /locus_tag="ROH59_002788"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HDX4805247.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFSQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIACPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(26188..27045)
                     /gene="entB"
                     /locus_tag="ROH59_002789"
     CDS             complement(26188..27045)
                     /gene="entB"
                     /locus_tag="ROH59_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HDX4805248.1"
                     /translation="MAIPKLQAYALPEPHDIPQNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(27059..28669)
                     /gene="entE"
                     /locus_tag="ROH59_002790"
     CDS             complement(27059..28669)
                     /gene="entE"
                     /locus_tag="ROH59_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HDX4805249.1"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GEWQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVAEHSSIRVVQLLNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALAEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRTSA"
     gene            complement(28679..29854)
                     /gene="entC"
                     /locus_tag="ROH59_002791"
     CDS             complement(28679..29854)
                     /gene="entC"
                     /locus_tag="ROH59_002791"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HDX4805250.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHLAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            30043..30999
                     /gene="fepB"
                     /locus_tag="ROH59_002792"
     CDS             30043..30999
                     /gene="fepB"
                     /locus_tag="ROH59_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HDX4805251.1"
                     /translation="MRLASLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIALFDKQLAAAKEQIKLPPQPVTALVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF"
     gene            complement(31003..32253)
                     /gene="entS"
                     /locus_tag="ROH59_002793"
     CDS             complement(31003..32253)
                     /gene="entS"
                     /locus_tag="ROH59_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HDX4805252.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLSVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMIGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSVRPGLLMLLSTLGAFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRRFRQTPPQVTASDN"
     gene            32364..33368
                     /gene="fepD"
                     /locus_tag="ROH59_002794"
     CDS             32364..33368
                     /gene="fepD"
                     /locus_tag="ROH59_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HDX4805253.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAL
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLMMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLTAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            33365..34357
                     /gene="fepG"
                     /locus_tag="ROH59_002795"
     CDS             33365..34357
                     /gene="fepG"
                     /locus_tag="ROH59_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HDX4805254.1"
                     /translation="MIYVSRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            34354..35169
                     /gene="fepC"
                     /locus_tag="ROH59_002796"
     CDS             34354..35169
                     /gene="fepC"
                     /locus_tag="ROH59_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HDX4805255.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEDAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTAKI"
     gene            complement(35166..36299)
                     /gene="fepE"
                     /locus_tag="ROH59_002797"
     CDS             complement(35166..36299)
                     /gene="fepE"
                     /locus_tag="ROH59_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
                     /protein_id="HDX4805256.1"
                     /translation="MSSLNIKQGSEAHFPEYPLASPSNNEIDLLNLIEVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKTFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDPLDLHRAIVALSEKMKAVDDNAS
                     KKKDESALYTSWTLSFTAPTSEEAQKVLAGYIDYISALVVKESIENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKTNVNDVNFTPFKYQLRPSLPVKKD
                     GQGKAIIVILSALVGGMVACGGVLLRHAMASRKQDAMMADHLV"
BASE COUNT         8785 a         9830 c         9049 g         8752 t
ORIGIN      
        1 ccgcagctaa caccttacaa ttaacaaatt tgcatcaatc cgccatcaat ttacacacat
       61 tattatgtga tatttgccaa ccgctaaata tgcgttttgt tatctacgta taaaaacagc
      121 aacttcaatg tcttaatggc agtttttctt gattttaatc agcattcacc gccaatttat
      181 tgggcatatt ttttccttaa cttttaggaa ttttttatta tttactttgg ggcctggaga
      241 caggaaaaat tatgctgaca ttcattgaac tccttattgg ggttgtggtt attgtgggtg
      301 tagctcgcta catcattaaa gggtattctg ccactggcgt gttatttgtc ggtggcctgt
      361 tattgctgat tatcagtgcc attatggggc acaaagtgtt accgtccagc caggcttcaa
      421 caggctacag cgccacggat atcgttgaat acgttaaaat attgctaatg agccgcggcg
      481 gcgacctcgg catgatgatt atgatgctgt gtggctttgc cgcttacatg acccatatcg
      541 gcgcgaatga tatggtggtc aagctggcgt caaaaccatt gcagtatatt aactcccctt
      601 accttctgat gattgccgcc tattttgttg cctgtctgat gtcactggcc gtctcttccg
      661 caaccggtct gggtgttttg ctgatggcaa ccctgtttcc ggtgatggta aacgttggta
      721 tcagtcgtgg cgcagctgct gccatttgtg cctccccggc ggcgattatt ctcgcaccga
      781 cttcagggga tgtggtgctg gcagcgcagg cttccgaaat gtcgctgatt gacttcgcct
      841 tcaaaacaac gctgcctatc tcaattgctg caattatcgg catggcgatc gcccacttct
      901 tctggcaacg ttatctggat aaaaaagagc acatctctca tgaaatgtta gatgtcagtg
      961 aaatcaccac cactgcccct gcgttttatg ccattttgcc gttcacgccg atcatcggag
     1021 tgctgatttt tgacggcaaa tggggtccgc aattacacat catcactatt ctggtgattt
     1081 gtatgctaat tgcctccatt ctggagttca tccgcagctt taatacccag aaagttttct
     1141 ctggtctgga agtggcttat cgcggtatgg cagatgcatt tgctaacgtg gtgatgctgc
     1201 tggttgccgc tggggtattc gctcaggggc ttagcaccat cggctttatt caaagtctga
     1261 tttctatcgc tacctcgttt ggttcggcga gtatcatcct gatgctggta ttggtgatcc
     1321 tgacaatgct ggcggcagtc acgaccggtt caggcaatgc gccgttttat gcgtttgttg
     1381 agatgatccc gaaactggcg cactcctccg gcattaaccc ggcgtatttg actatcccga
     1441 tgctgcaggc gtcaaacctg ggtcgtaccc tatcacccgt ttctggcgta gtcgttgcgg
     1501 ttgccgggat ggcgaagatc tcgccgtttg aagtcgtaaa acgcacctcg gtgccggtgc
     1561 ttgttggttt ggtgattgtt atcgttgcta cagagctgat ggtgccagga acggcagcag
     1621 cggtcacagg caagtaaata gtaatgccgg aggcaagttt cctccggctt tatcatgtca
     1681 cccactgtgg tatatgcgtt gcggtctgcc aactttgccg tgaacaattt cagcaataat
     1741 cagatggcgg ctggcgcaat attcaagata acgcctggca gtggtgcgac tgatggtcag
     1801 tgcctgcgcc accgtttctg ccgtatgttg cacaccaggc tctttgaaca gttttcgcac
     1861 cgcgtttagc gtcaaggggt caatgccggt cggcagttcg tctttgggtt caccgcgagc
     1921 ataggcatta aacatctcat caatttgctt ctggctggcg ctatcaatac tttccagcat
     1981 atgtttacgc tggcggaaac gggttagcgt ttgccccaga cgttcatagg caattggctt
     2041 aatgagataa tcaaatacac cacaacgtac ggcttcagac accgtttcca tatcgctggc
     2101 tgcagtggta aacaccacgt cgccgggata atgcgcctgc accagttcat gcagtaaatt
     2161 aatccctcta ccgtcaggaa gatagttatc gagcaagatt agccccggct taaaacgctc
     2221 gatcatcatt cgggcctgcg ccaggtttcc cgccagtaat atctggctga atccgggaat
     2281 gtgacgaata tattccgcat gcatctctgc cagcggcgtt tcgtcctcaa cgatcaatag
     2341 ggttaatgga gctgtcatta ggtttcactt tcggaatata gattgaaaat aaggtaccgc
     2401 agggatcatt atcttcgaga gtgataacac caccgcagcg cgttacgtag ctggcaatca
     2461 agtacaaccc aatgccatgt tcaccgggct cgtcagcacg cgtactgaca ccctgctcaa
     2521 atattttgtc tcgtagagac tctggaacgc cgcagccctg atcggcgact tcaatcacca
     2581 catcatcgcc ttcatcgctg aggtataatt caacaatctt gtttccttca tcgctacgca
     2641 ggcttgcttc gaaggcgtta tcaagtaaat tgccaacaat ggctgcaaac tcggtgctgt
     2701 ccagtcctgg cggcagttgc gaaagctggc taccggggac gatgaccatt tttagcccca
     2761 gttcgcgggc gcgctgcact ttaccaaaaa gcagccccgc cacctggcga tcggcaaacg
     2821 cctcacgcag gctgtcaata agctgttgct gggcctgaga ctcaccctgc accatcgcca
     2881 gcacgcgatc atactctttc atctgcaaca gaccattgag cgtcgacatc caattgagat
     2941 gctcgtgtcg caatgtacga aggctctcga cgtattgttt aatttgcgtc agttgcgcat
     3001 tgagggtgga aatttcgtct ttactacgaa agctgataat ggcccccagc aaatcatcgc
     3061 cagaacgaat agcttcccga ttggcgataa cgctcagacc gttaaagttc gccaccacat
     3121 cctgacgttt ttcatcaatc tgttcggtaa agaaatcggc gggcctgacc acttcagcaa
     3181 tgggtttacc caaccattgc cgtccggggg agctcagccc cagcatcttt cttgcgttac
     3241 gattgatggc ggtaatgtac ccgtgcggat ccaccgcaat cagcccttca taaaccgaac
     3301 taaacagcgc ctcttgctga cggaccacgc gtgcgatttg ctttggctcc atgcccatca
     3361 tctgccgacg gatatgcgcg gccaggaacc acgatagcaa catcaaaatc cctaacagca
     3421 cgacaaacac gcctgccatc ggtaataaaa actcagcccg ccagctatcg attttactca
     3481 ccagatagcc aatcgacacc acaccgatga cttttccatc gtcatcaaag attggcgttt
     3541 tggcacgcat cgccatgcca attgaccctt tcccggtgat gaagtagctc tcccctttct
     3601 ccagcgcgcc cggtttggtg aactgcatag gataaccaat tttctccgga ttaggatggt
     3661 aaagacgaat cgagtgccgg tcgccaatca ccacataatc gaaatcagta tctctttgta
     3721 atttgtcagc gatggtcgcc agcctcttgt agtcacgcgt tttcactgcg ctgatgatac
     3781 tgtcattaga agcaataatt tttgcctgat tcattgccat gtcgcgcaca tgaagcgtta
     3841 aatagtcctc aaaactggcc gtaaaatatt gcgccagggc tgcaatgaca aatattgaga
     3901 acaccagaat cagcaaaaag atacgcagcg gaaatgccag tctttggaaa aatgcaaact
     3961 gtttattctc gttaagctgc aacattgttt tccttgcggg ttgtcccgag cctctttgac
     4021 ggatgtaatt aaaatgttga ataaaaatac atagatatta aatatgatcg tggcaaattt
     4081 tattcattaa atcaattaaa tcacttaaac ctgcgggtta tttcgtaatt acattagtta
     4141 aaaaacttaa aaccattaaa taaataaaaa accactaact ctatgtgaaa taaatcaaaa
     4201 tttcacgccg aaatactcct taggatgtat agcgaaagga gaaaaagata tacctcgatc
     4261 accccccttt ctcccaagtg aaaataaaag gttatcaatt tgcaacattg aacaacattc
     4321 gttgcaaatc gataacaaca tgcaccttca ggatactatt tattatgttc ggcaatgata
     4381 ttttcacccg cgtaaaacgt tcagaaaata aaaaaatggc ggaaatcgcc caattcctgc
     4441 atgaaaatga tttgagcgtt gacaccacag tcgaagtatt tattaccgta acccgcgatg
     4501 aaaagcttat cgcgtgcggt ggaattgccg gaaatattat taaatgcgtt gctatcagtg
     4561 aatccgttcg cggtgaagga ctggcgctga cattagccac tgaactgata aacctcgcct
     4621 atgagcggca cagcacgcat ctgtttattt ataccaaaac cgaatacgag gcgctgttcc
     4681 gccagtgcgg tttttccacg ctgaccagcg tacccggcgt gatggtgctg atggaaaaca
     4741 gcgccacgcg actgaaacgc tatgccgaat cgctgaaaaa atttcgtcat ccagggaaca
     4801 aaattggctg cattgtgatg aacgccaatc cctttacgaa tggtcaccgt tatctgattc
     4861 aacaggctgc ggcacaatgc gactggttgc atctgttttt agtcaaagaa gattcttcac
     4921 gcttccccta tgaagaccgg ctggatctgg tgttaaaagg caccgccgat attccacgcc
     4981 tgactgtgca tcgcggctcc gaatacatca tctcccgcgc aacgttccct tgctacttca
     5041 ttaaagaaca gagcgtcatt aaccattgct acaccgaaat tgatctgaag attttccgtc
     5101 agtacctcgc tcccgcgctg ggtgtaactc accgctttgt cggtactgaa cccttttgtc
     5161 gcgttaccgc ccagtacaac caggatatgc gctactggct ggaaacgccg actatctccg
     5221 caccgcccat cgaactagtt gaaattgagc ggctgcgtta ccaggagatg ccgatatccg
     5281 cttcccgggt acgtcaactg ctggcaaaaa acgatctcac ggctatcgcg ccgctggtcc
     5341 ctgcagtcac gctgcattat ttgcagaacc tgcttgagca ctcccgccag gacgcggcag
     5401 ctcgtcaaaa gacccccgca tgagaaacag gtgaaaaatg aaaataaacc agcccgccgt
     5461 tgcaggcacc cttgagtctg gggatgtgat gatacgcatc gccccactcg atacgcagga
     5521 tatcgacctg caaatcaaca gcagcgttga gaaacagttt ggcgatgcaa ttcgcaccac
     5581 cattctggac gttctcgccc gctacaacgt gcgcggcgta cagctgaatg tcgatgacaa
     5641 aggcgcactg gactgcattt tacgtgcacg actggaagcc ctgctggcac gcgccagcgg
     5701 tatcccggct ctgccatggg aggattgcca atgatttccg cttcgctgca acaacgtaaa
     5761 actcgcaccc gccgcagtat gttgtttgtg cctggtgcta atgccgcgat ggtcagcaac
     5821 tccttcatct acccggctga tgccctgatg tttgacctcg aagactccgt agcattgcgt
     5881 gaaaaagaca ccgcccgccg catggtttac cacgcgctgc aacatccgct ttatcgcgat
     5941 attgaaacca ttgtgcgtgt aaacgcgctg gattccgaat ggggtgttaa cgacctggaa
     6001 gccgtcgttc gcggtggtgc ggacgttgtg cgtctgccga aaaccgatac cgctcaggat
     6061 gttctggata tcgaaaaaga gatcctgcgt atcgaaaaag cctgtggtcg tgaacccggc
     6121 agtaccggcc tgctggcggc gattgaatct ccgctgggca ttacccgcgc agtggaaatc
     6181 gctcacgctt ccgagcgttt gatcggtatc gccctcggcg cagaagacta tgtgcgcaac
     6241 ctgcgtacag aacgctcccc ggaaggaact gaactgctgt tcgctcgctg ctccattttg
     6301 caggccgcgc gctctgcggg tattcaggcg ttcgataccg tctattccga cgctaacaac
     6361 gaagccggat tcctgcaaga agccgcccac atcaaacagc tgggctttga cggcaaatcg
     6421 ctgatcaacc cgcgtcagat tgatctgctg cacaacctct acgcaccgac ccagaaagaa
     6481 gtggatcacg cccgccgcgt cgtagaagcc gctgaagccg ccgctcgcga aggcctcggc
     6541 gtggtttccc tgaacggcaa gatggtggac ggtccggtta tcgatcgcgc ccgtctggtg
     6601 ctctcccgtg cagaactttc cggcatccgc gaagaataag gcaatcaaaa tgacgcagaa
     6661 aattgaacaa tctcaacgac aagaacgggt agcggcctgg aatcgtcgcg ctgaatgcga
     6721 tcttgccgct ttccagaact cgccaaagca aacctaccag gctgaaaaag cgcgcgatcg
     6781 caaactgtgc gccgatctgg aagaagcgat tcgtcgctct ggtttacagg acggcatgac
     6841 ggtttccttc catcacgctt tccgtggcgg tgacctgacc gtcaatatgg tgatggacgt
     6901 catcgcgaag atgggcttta aaaacctgac tctggcctcc agctccctga gtgattgcca
     6961 tgcgccgctg gtagaacaca ttcgccaggg cgtggttacc cgcatttata cctctggcct
     7021 gcgcggtcca ctggcggaag aaatctcccg tggtctgctg gcggaaccgg tgcaaatcca
     7081 ctctcacggc ggacgtgtgc atctggtaca gagcggcgaa ctgaatatcg atgtggcttt
     7141 cctcggcgtc ccgtcctgtg atgaattcgg taatgccaac ggctactccg gtaaagcctg
     7201 ctgcggctcc ctcggctatg caatggttga tgccgacaac gcaaaacagg tcgtgatgct
     7261 taccgaagaa ctgctgcctt atccgcataa tccggcaagc attgagcaag atcaggttga
     7321 tctgatcgtc aaagttgatc gcgttggcga tgctgcaaaa atcggcgctg gtgctacccg
     7381 tatgaccact aacccgcgcg aactgcttat tgcccgtagc gctgcggatg tgattgttaa
     7441 ctctggctac ttcaaagaag gtttctccat gcagaccggc accggcggcg cttcgctggc
     7501 ggtaacccgt ttcctggaag acaaaatgcg tagccgcgat attcgcgccg acttcgccct
     7561 cggcggtatt accgcgacga tggttgacct gcacgaaaaa ggtctgatcc gcaaactgct
     7621 ggatgtgcag agctttgaca gccaagctgc gcaatcgctg gcccgtaacc ccaatcacat
     7681 cgaaatcagc gccaaccaat acgctaactg ggggtcgaaa ggcgcatcgg ttgatcgtct
     7741 cgacgtggtg gtactgagtg cgctggaaat tgacacccag ttcaacgtta acgtgctgac
     7801 cggctctgac ggcgtactgc gtggtgcttc cggtggtcac tgcgataccg cgattgcctc
     7861 tgcgctttcc atcatcgtcg cgccgctggt acgcggtcgt attccgacgc tggtggataa
     7921 cgtgctgacc tgcatcaccc cgggctccag tgtcgatatt ctggtcacag accacggcat
     7981 cgctgttaac ccggcacgtc cggagctggc agaacgtctg caggaagcgg ggatcaaagt
     8041 ggtttctatt gagtggctgc gtgaacgtgc gcgtctgctg accggtgaac cacagccgat
     8101 tgaattcacc gaccgcgtcg ttgccgttgt gcgttaccgc gatggctcgg tgatcgatgt
     8161 tgtgcatcag gtgaaggaat aagccatgca cctgcttcct gaactcgcca gccaccatgc
     8221 ggtgtcaatt cccgagctgc tcgtcagccg ggatgaaagg caagcacggc aacacgcctg
     8281 gctcaagcgc catcctgttc cactggtctc ctttaccgtg gttgcgccag ggccgattaa
     8341 agacagcgag gtcacacgcc gaatttttaa tcatggcgtg acagccttgc gtgccttagc
     8401 cgcaaaacag ggctggcaaa ttcaggagca ggctgcactg gtttccgcca gcgggccgga
     8461 gggcatgttg agcattgccg ccccggctcg cgacctcaag ctcgccacca ttgagcttga
     8521 acatagtcat cctctcgggc ggttatggga tatcgatgtc ctgacgcccg aaggcgacat
     8581 tctctcccgc cgcgattatt cactgccgcc tcgccgctgc ctgttgtgcg agcaaagcgc
     8641 agctgtttgc gcgcgtggaa aaacccatca actgaccgat ttactcaacc gcatggaggc
     8701 gctgctaaac gatgtcgatg cctgcaacgt caactaaaac cacaaagctt gcgacgtcat
     8761 taattgatga gtacgccctg ctgggctggc gcgccatgct gactgaagtc aacctgtcac
     8821 cgaaaccagg cctcgtggat cgcattaact gcggtgcgca caaagatatg gcgctggaag
     8881 atttccaccg cagcgcgctg gcgattcagg gctggttacc ccgtttcatt gaatttggtg
     8941 cctgtagtgc agaaatggca ccggaagcgg tactcaacgg attacgccca attggtatgg
     9001 cttgcgaagg tgatatgttc cgcgccactg cgggcgtaaa cacgcataaa ggaagcattt
     9061 tttctttagg gctactgtgt gcggcaattg gccgtttgct tcagctcaac cagccggtaa
     9121 cgccaacaac cgtttgttct acggcggcaa gtttctgccg tggcctgacc gatcgcgaac
     9181 tgcgtaccaa taattcacga ctgacggcag gtcaacggtt gtaccagcag cttggcctta
     9241 ccggcgcacg cggtgaagcc gaagcaggtt atccactggt aatcaaccac gccttgccgc
     9301 attacctcac tctgctggat caggggttag atcctgaact ggcactgctc gataccttgc
     9361 tcctactgat ggctaccaac ggcgatacca acgttgcatc gcgcggtggc gaggggggcc
     9421 tgcgctggct acagcgcgag gcgcaaacac tattaaacaa tgggggcatc cgaacccccg
     9481 ccgatctcga ttatctccgg cagttcgaca gggagtgtat cgaacgaaat ctcagtccag
     9541 gcggcagtgc cgacctgctg attcttacct ggtttttagc acagatttaa ttatttaagc
     9601 acttgataaa tttggaaata ttaattttcg gagaacccgt atgtctttag caaaagataa
     9661 tatatggaaa ctattggcgc ccctggtggt gatgggtgtc atgtttctta tccctgtacc
     9721 tgacggtatg ccgccgcagg cgtggcatta ctttgcagtg tttgtggcaa tgattgtcgg
     9781 catgatcctc gagccaattc cggcaacggc gatcagtttt attgcggtta ctatttgcgt
     9841 tattggcagt aattacctgc tctttgatgc caaagaatta gctgacccag cgtttaatgc
     9901 gcaaaaacag gcgctgaaat ggggtctggc tggtttttcc agcaccacgg tatggctggt
     9961 atttggcgca tttatttttg cattagggta tgaagtttcc gggttaggcc gtcgtattgc
    10021 ccttttcctg gtgaaattca tggggaaacg cacgctgacg ttgggttatg cgattgtcat
    10081 tatcgacatt ctgctggcac cgtttacacc gtccaacacc gcgcgtaccg ggggtacggt
    10141 ttttccggtc attaaaaacc tgccgccgct gtttaaatca ttcccgaacg atccgtccgc
    10201 gcgtcgtatt ggcggctatt tgatgtggat gatggtcatt agtaccagtc tgagttcgtc
    10261 catgtttgtc accggtgcgg caccaaacgt gctgggtctg gagttcgtca gcaaaattgc
    10321 cggtatccag attagctggt tgcagtggtt cctctgcttc ctgccggttg gggttatctt
    10381 gcttatcatt gcgccgtggc tttcctacgt gctgtacaaa ccggaaatca cacacagtga
    10441 agaagtggca acctgggcgg gtgatgaact aaaaaccatg ggtgcgctga cgcgcagaga
    10501 gtggacgctg attggccttg tattgctcag cttaggtttg tgggtatttg gcagtgaagt
    10561 cattaatgct actgcggtag gtctgctggc agtttcgctg atgctggcgc tgcacgttgt
    10621 gccgtggaaa gacattactc gctataacag cgcatggaac acgctggtca acctggcaac
    10681 gctggttgtt atggcgaatg gcctgacccg ttctggcttt atcgactggt tcgccaacac
    10741 gatgagtaca cacctggaag gcttctcacc aaacgcaacg gtgattgtac tggttctggt
    10801 gttctacttt gcacactacc tgtttgccag cctgtctgcg cacaccgcaa ccatgctgcc
    10861 ggttattctg gccgtcggta aagggattcc gggcgtacca atggaacaac tgtgtatcct
    10921 gctggtgctg tctatcggta tcatgggctg tctgacgcct tatgcaaccg gtcctggggt
    10981 gattatttac ggctgtggct atgtgaaatc aaaagattac tggcgtcttg gcgcaatctt
    11041 cggggtgatt tacatctcta tgctgctgtt ggttggctgg ccgattctcg ccatgtggaa
    11101 ctaatacgtt cgccaaacgc tgaataaatc atcacgcccg ccaggtaagc ccacctggcg
    11161 ggctttttta tgatttaata gataatattc agtgtatgta tgagttccac acccattatg
    11221 aaagcattct ggcgtaacgc cgcgttgctc gcggtttctc tgcttccctt ctcttctgcc
    11281 aacgccgtgg cgttgcaggc aaaacagtat ggcgattttg atcgctatgt cctggccctc
    11341 tcctggcaaa ccggattttg ccagagtcaa cacgatcgaa atcgtaacga acgagatgaa
    11401 tgtcgcctgc aaaccgaaac gaccaacaaa gctgattttt tgaccgtaca tggtctgtgg
    11461 ccaggattgc ctaaatcggt tgctgcccgt ggtgttgatg aacgccgctg gatgcgcttc
    11521 ggttgcgcta ctcgcccaat cccgaatctg ccagaagcac gcgccagccg gatgtgttca
    11581 tcgccggaaa ccgggttatc gctggaaacg gcagctaaac taagtgaagt catgccagga
    11641 gctggcggac gttcctgcct ggaacgctac gaatatgcca aacacggtgc ctgctttggt
    11701 tttgatccag acgcatactt cggcacgatg gtacgcctga atcaagaaat taaagagagc
    11761 gaagccggaa aattccttgc ggataactac ggtaaaacag tgagccgccg tgactttgat
    11821 gccgcctttg ccaaaagctg gggaaaagag aacgtgaaag cagttaagct aacgtgccag
    11881 ggtaaccctg cgtatttgac tgaaattcag atctcgatca aagctgacgc catcaacgct
    11941 ccgctttctg ccaactcatt cttgccacaa ccacacccag gcaactgtgg caaaaccttt
    12001 gtgattgata aagcaggtta ttaatcctct gatttacaaa acacgctaat tcgtcttcca
    12061 taaaccatga cgattaagat ttatacataa tgcgctacat tgaggaattc cctgaatgtg
    12121 acgcaaatca cttcaaagag tgagcaacag tcagtatcat catgtgagtt aaaccctcgc
    12181 cgcctgacgg tgagggtttt cttttgggta tgtttatctg cgacactcgc agtaccgacg
    12241 acatggagta aaaatgtcca gaccaactat catcattaac gacctggatg ccgaacgcat
    12301 cgatattctg ctggagcaac ccgcctatgc tggtttgcca atcgccgacg cgttaaacgc
    12361 agagttggat cgcgcccaaa tgtgttcgcc agaagagatg ccacacgacg tggtgacaat
    12421 gaacagccgg gttaaattcc gcaatcttag cgatggcgaa gtgcgtgtgc gcacgctggt
    12481 gtatccggca aaaatgaccg atagcaatac tcagctttcc gttatggctc cggtaggtgc
    12541 cgcactgctg gggctgcgcg ttggcgattc cattcactgg gaacttccgg gcggcgttgc
    12601 aacccacctt gaagtgctgg aactcgaata ccagccagaa gctgctggcg actacctgct
    12661 ttaatcccat ctgcacaagc gataactcgc tttgcccaga ggatgcactc gcatcctctt
    12721 tccgctcaaa tatcaaccag atttatcatt ttgctcttaa gcgcagcatt ctaatctgaa
    12781 ctggttattc atctgcggaa cctcatatga gcgaagctct cggtatcact gcattttata
    12841 tattcatagc agcaattatt gttgctgcag tgctatacct tgaacaacgc tggtagcgcc
    12901 tggttttatt tattttccag ctcaatagca aattcagatc aaatcagcct cgcaaattat
    12961 agattcataa ccaataatgt gctgttatgt atacatgcaa aaacaaggag agaatgctta
    13021 tgtacaaaac aatcatcatg ccagtggatg ttttcgaaat ggaattgagc gacaaagcga
    13081 ttcgccacgc tgaattcctc gcccaggatg acggagttat tcatctactt cacgtactac
    13141 cggggtcagc cagcctgagc ctgcaccgtt ttgccgctga tgtacgtcgt tttgaagagc
    13201 atctgcaaca tgaagcagaa gaacgtttgc aaacgatggt cagccacttc accatcgatc
    13261 cttcccgcat taagcaacat gtccgttttg gtagtgtgcg ggatgaagtt aacgagttag
    13321 cgaaagaact tgatgcagat gtagtagtga ttggttcgcg taacccatca atttcaactc
    13381 atctgttggg ttctaacgcc tcgagcgtaa tccgccacgc caatttgccg gtgctggttg
    13441 tgcgttaatt gccagaataa gtctcccgcc ctgcccggag ccatccctgc agggcttttt
    13501 aatgccataa aaaagccgcc aggtttgacc ccggcggcta agcaattaca ggtgaatctt
    13561 acttcttctt atgcagtttt ggtgcgaatc aggtagtcaa aagcactcag agaggctttg
    13621 gcaccttcgc cagtggcgat gatgatctgc ttgtacggaa ccgtcgtaca gtcacccgct
    13681 gcgaacacgc ctttgacgtt ggtttcgcat ttcgcatcaa tgataatctc gcccatgcga
    13741 ttacgttcga ctgcgccttc cagccagttg gtgttcggca gcagaccaat ctggacgaaa
    13801 ataccggcca gttcgatgtt gtgaatatcg ccgctgacac gatcgcgata ttccagacct
    13861 acgactttgc taccgtcgcc tttcacttcc gtggtttgcg cattcagaat aatgtcgacg
    13921 tttttcaggc tgcgtagttt gtcctgcaga acctggtcgg ctttcatttc tggcgcaaat
    13981 tccagcagcg ttacgtgctc aacgataccc gccaggtcaa ttgccgcttc cacgccggag
    14041 ttaccgccgc cgataaccgc tacgcgtttg cctttaaaca gcgggccgtc gcagtgcggg
    14101 cagtaggtca cgcctttggt gcgatactga tcttcgccag gaacgttcat gttgcgccat
    14161 tttgcaccag tcgccacgat aatgctgcgt gctttcagta ccgcgccaga agctgtttca
    14221 atctgatgca ggccgccttc aaccgctgcc gggatcagtt tgctcgcgct ctggctgtcg
    14281 atcacatcaa cgtcgtattc atcaacatga actttcagcg cacctgccag tttctggcct
    14341 tcggtcttcg gtacagaaat gtagttttcg atatcaacgg tatcgaggat ctgaccacca
    14401 aaacgttcgc ccatcagacc ggtacggatg cctttacgtg cggagtaaat tgctgccgct
    14461 gcacccgcag ggccggaacc aacgattaat acgtcataag catcacgctt gttcagctct
    14521 tctgccgcac gtttttccgc accagtatca attttggcaa cgatttcagt caacgtcatg
    14581 cggccctgac caaactcttt cccgtttacg aacactgccg gaacgcccat cacgttgcga
    14641 tcggtgattt cgttctggaa ggtgccgccg tcaattgcag tgtgcttgat gcgcgggttc
    14701 agtacgctca tcaggttcag cgcctgcacc acgtccgggc agttgtggca agagagcgaa
    14761 taataggttt cgaattcaaa atcaccgtca atatggcgaa tctgctccag cagagactgc
    14821 gcttctttcg acggatgacc accggtccac aacaacgcca gtaccagcga ggtgaactcg
    14881 tggcccagcg gggaacctgc aaaacgtggc ccctggttgg aaccagggtt ggtaatcagg
    14941 aaagacggct tacgcaccgg caagctgtta tcttctttaa aggtgacttt gtctgacagt
    15001 tctgcgattt cagccaacag ttccttgatt tctgccgatt tagcgctgtc atccagcgtg
    15061 gcaattaact caacaggctt ggtcaatttc tcaaggtaag ccttgagttg agttttcata
    15121 tttgtgtcga gcatgtttat ctcctgggct ttaaacatca tcatgcaagc ggcctctgcg
    15181 gctagctgga tgcagcttgc atcatggtgc ggggaagaaa atcgggtgcc gcagcacccg
    15241 aagaattagg tgaatttccg aagtatctcg cgccggagtt gatagcgcga aagacgaagg
    15301 aaatttagat tttaccaacc aggtccagag acggagccag agttgcttca ccttctttcc
    15361 atttagccgg gcaaacttca cctgggtgag aagctacgta ctgtgctgct ttgattttac
    15421 gcagcaggtc agacgcgtca cggccaatgc cttcagcggt aacttcgatt gcctggatga
    15481 taccctgcgg gtcaacaacg aaggtcgcac ggtcagccag accttcatct tcacgcatgt
    15541 tgtcgaagtt acgggtcagg gcgccagtcg ggtcgccgat catcgcatat ttgattttag
    15601 cgatggtttc agagctgctg tgccatgctt tgtgggtgaa gtgagtatcg gtagatactg
    15661 cgtatacgtc tacgcccagt ttctgcagtt cttcgtaatg gtcagcaacg tcacccagtt
    15721 cggtcgggca tacgaaagta aagtcagccg ggtagaagaa gaagacgctc cagcggcctt
    15781 cggtatcttt ttcggtgatt tcgatgaatt cgccgttttt gaatgcctgg tttttaaaag
    15841 gtttaatttt ggtgttaatc aaggacatct atacttcctc cgtgttttcg atgagatgta
    15901 aggtaaccaa tttttgccga ttcggctaat gcgtttccat tatcaaatcg ataagtttta
    15961 ccttacaacc ttcgtaagac aactttgtga actttgcacc gccagcggcg ataaaaagta
    16021 aaatggcccc ctttccaggt gaccgtgtaa tctgaactac cctttggtat cttcagcacc
    16081 tgcctgcagg ctgaggtgtt gcccttacaa atgcaacaac gacatggatt acaacaccct
    16141 cataaacaaa gggcaatcac ctgatctaag ctcttaccta tgacagtgat aggttatgcc
    16201 ttttactcga cttttgcact gactgaaaag gacaaattaa tgttaaaaaa gatactttta
    16261 ctggccctgc ttcctgcaat cgccttcgca gaggaacttc ctgccccagt aaaagcgatt
    16321 gaaaaacagg gtattacaat catcaaaacg ttcgatgccc ctggaggaat gaaaggttat
    16381 ctcggtaagt atcaggatat gggcgtcacc atctacctga ctccagatgg taagcacgct
    16441 atctctggtt acatgtacaa cgaaaaaggt gaaaacctga gtaacacgct tatcgaaaaa
    16501 gaaatttacg cacccgccgg acgtgaaatg tggcaacgga tggaacaatc ccactggctc
    16561 ctcgacggta aaaaagacgc gccggtcatt gtctacgtct tcgccgatcc gttctgccca
    16621 tattgtaaac agttctggca gcaggctcgt ccgtgggtag attctggcaa agtgcaattg
    16681 agaacattgt tggttggggt tatcaagcca gaaagcccgg cgacagcagc ggcaattctt
    16741 gcctccaaag atcccgcaaa aacctggcaa caatatgaag cctctggtgg caagcttaag
    16801 ctaagcgtgc ctgcaaacgt aagcacagag caaatgaaag tgttaagcga caacgagaaa
    16861 ctcatggacg atctgggggc aaatgtcaca ccagctatct attacatgag taaggaaaat
    16921 accctgcaac aagccgtcgg attacccgat cagaaaacgc ttaatatcat tatgaggaat
    16981 aaataaaaga taattcatgg atggttgaaa tacatcattg cttttcaacc atcctaaaaa
    17041 cgcatgaatt gctcgtaacc cacctgacag ctatgctatt ttagaaaatc ttaatccaaa
    17101 gttaagcaga aaaacataat acatataaat acaacaacat tattgatcaa gtgaatgatt
    17161 tatggaagag acaatacaac ggagtatgtt atggctaatc tttatgatct aaaaaaattt
    17221 gacctcaatt tactggttat atttgaatgt atttatcaac atctcagcat tagtaaagcg
    17281 gcagaatcat tatatataac accctctgct gttagtcagt cgttacaacg tttacgtgcg
    17341 caatttaatg acccgttatt cattcgctca gggaaaggta tcgcgccgac tacaacaggg
    17401 ttaaacctgc atcaccatct tgagaaaaat ctcagaggcc ttgaacaaac gatcaatatc
    17461 gttaataagt ctgaactaaa gaaaaatttt attatctacg gtcctcagct tatttcttgt
    17521 actaataaca acatgctaat ccgctgtctt agacaagata cttcaatcga tatagaatgc
    17581 catgacatac tgctttcagc tgaaaatgcc gaagaactgt tggttcaacg caaaactgac
    17641 ctggcaatta cgctgcaacc agtaattagt cgctctgtca tctgcatgcc gttacacact
    17701 attcgcaatt cccttatatg tagcaacaaa catcctcgta ttactgatac cagtaactat
    17761 gaacaaatta tcgccgaaga attcaccctg ttgatatcta aatcagcagg gattgacgaa
    17821 attcaaatgg acatagatga acgttttata aaccgtaaag tttcatttcg cagttcttct
    17881 ttgttgacta taattaatag catttctgtt actgacttat taggcattgt gcccaccgaa
    17941 ctgtacgatt tacatcgtga ctttttgaag ttaaaagaaa taaaactgga acaacctctt
    18001 cctgcggtta aactttatat ttcctataac aaggcttcgt tgaacaacct tgtcttctct
    18061 cgattcatag atcgtttaaa tgatagcttc tgattcatta ccactgacaa ataatatatt
    18121 acgcatcaat taattcattg tgtgaatata aaataatgtg ctctatcttg cttcgtttat
    18181 cctataatta gcggattcat ctcacgagtc accccgtaac gttcagagag cgtttttaga
    18241 tgtctattta taaaatcccg cttccactga atattctgga agctgcaaaa gaacgtatta
    18301 cctggacact taatacccta ccccgtatct gtgtttcttt ttcgggtggt aaagattccg
    18361 gattaatgct gcatctgaca gctgaaattg cccgacaaat gggcaaaaaa atctgcgttt
    18421 tgtttatcga ctgggaagcg cagttctcat gcactattaa ctatgttcag tcattacgtg
    18481 agttttacgc cgatgtcatc gaagagtttt actgggttgc gctcccgctt acgacgcaaa
    18541 attccctttc tcaataccaa cccgaatggc agtgctggga acctgatgtc gaatgggtgc
    18601 gtcagccccc gcaagatgcg ataaccgatc ctgacttttt ctccttttac cagcctggca
    18661 tgaccttcga acaatttgtg cgtgagtttg ctgaatggtt ttcacaaaaa cgtccggcgg
    18721 cgatgatgat cggcatccgt gcagatgagt cctacaaccg ttttgtcgcc atcgccagtt
    18781 taaataaaca acgttttgcc gatgataagc cctggaccac cgccgcacca ggcggtcata
    18841 gctggtacat ttaccccatc tacgactgga aagtggctga tatctggacc tggtatgcta
    18901 accatcaaca gctctgtaac ccactgtata atataatgta tcaggcaggc gtccctctgc
    18961 gtcatatgcg aatttgcgaa ccttttggcc cggagcaacg gcaaggatta tggctctatc
    19021 acgttatcga accggatcgc tgggctgcta tgtgcgcacg agtcagcggg gtaaaaagtg
    19081 gcggcattta cgccggacat gataatcatt tttatggtca tcggaaaatc ctcaagccag
    19141 aacatttaga ctggcaagaa tatgcattat tgctgctcaa tagcatgccg gaaaaaacag
    19201 cggagcatta ccgcaataaa atcgccattt atttgcactg gtatcagaaa aaaagcatca
    19261 cggttccaca aactcagcaa ggggacattg gggcgaaaga tatcccctcc tggcggcgaa
    19321 tatgcaaagt tttactcaat aacgattact ggtgtcgggc attatcattt agccctacga
    19381 aagcgaagaa ctatcagcgt tataacgaac ggataaaagg aaaacgtaag gaatggggga
    19441 tactatgcaa caacgattaa cgcaggattt aacccaattt ctcgccagct tgccggaaga
    19501 tgatcgcatc aacgcgatta atgaaatccg catggcgatc catcaggtta gcccctttcg
    19561 tgaagagcca gtggattgcg ttctgtgggt taaaaacagc caacttatgc ctaatgatta
    19621 caacccaaac aacgtggcac cacccgaaaa aaaactgctg aaaaaatcca ttgaaataga
    19681 tggttttacc caacccattg tggtcacgca tacggataaa aatgccctgg aaatcgtgga
    19741 tggttttcac cgccatgaaa ttggtaaagg ctcatcatcg ttaaaattac gcttaaaagg
    19801 ttatttgccg gtgacctgtc tggaaggtac gcgtaatcaa cgcatcgccg cgactattcg
    19861 tcataatcgc gctcgtggac gtcaccaaat cactgccatg tcagaaatcg tccgagaact
    19921 cagccagttg ggatgggacg ataataaaat tggcaaagag ctgggaatgg acagcgacga
    19981 agtgttacgc ctgaagcaaa ttaacggcct gcaagagttg tttgccgacc gtcaattttc
    20041 ccgcgcctgg acggttaaat aactacagct ggcgcaggcg ttctgctgct gccagcaacg
    20101 tcgattcctt cttggcaaaa cagagacgaa tcagtttatg tgggaaggga tcggcgcaaa
    20161 acaccgacag cggaatcgcc gctacgccgt gctcccgcgt cagccactgg caaaactcaa
    20221 catcatccat cgtagatacg gcgctgtaat ccaccagcaa aaagtatgta ccttcgcacg
    20281 gtaaaatctc cagccgactt tcatttaagg cattcaccag aatatcgcgc ttctggcgat
    20341 aaaagtccgg taatgcaaga taatgctcag gttctgcacg tagcatatcg gcaagcgcca
    20401 gttgtgccgg ggtattcacc gaaaaggtca gatactgatg cactttgcgg atctcggcgc
    20461 tgatgggcgc aggcgcaacg caataaccca ctttccagcc ggtcatatga taggtcttac
    20521 caaacgatga caccgccacc gctcgctcac gcaattgcgg atgcgccagc acgctggcat
    20581 ggccctgttg tgaaaaattg atgtgctcgt agacttcatc gctaatgaca aaaatctcgt
    20641 gcccggcgat cgcctgccac agagcggcga aatcagtctg ctgccagaca gttgcactgg
    20701 ggttatgcgg ggtgttgagg atcaccagtc gggtgcgctc gcttaacaat gcggcaaatt
    20761 cctgccagtc aacgcgaaaa tgcggcggtt gcagtgcaat acgtttcact attccccccg
    20821 aaagtgcgat ggcgggggcg taactgtcat agctgggatc aaaacaaatc acttcgtcgc
    20881 cattgcgcac caatgcggtt atcgccgcgt ataacgcctc cgtcgcccct gccgtcacgg
    20941 tgatattgct gtcgacatcc ggttgatagc catacagacg ttccgttttc tgagcaatcg
    21001 cctcgcgcaa ggcctgcacg ccggtcatgg gtgcgtattg gtttgccccc tgggcaacgt
    21061 ggtacgccag ccgctcctgt aaatagcgcg gaccatcaaa atcaggaaag ccttgcgaaa
    21121 ggttaatcgc ctggtgttgc tgcgccagcg cgctcatctt ggtgaaaata gtggtgccaa
    21181 gttgtggaag tttgctttgt ggaatcagag ggttatttgt catttttatt gtacctgacg
    21241 aagttgcgtg ttgaaggcac tataacacga tgctagtatt tggcaatcaa gacgtttaga
    21301 tgtctaaata aaacaataag gacaacacaa catgcctcac aatcctatcc gcgtggtcgt
    21361 cggcccggct aactactttt cacatcccgg aagtttcaat cacctgcacg attttttcac
    21421 tgatgaacaa ctttctcgcg cggtgtggat ctacggcgaa cgcgccattg ctgcggcaca
    21481 aaccaaactg ccgcctgcgt ttgaactgcc aggggtaaag catattttgt ttcgtggtca
    21541 ttgcagcgaa agcgacgtgc aacaactggc ggcggagtcc ggtgacgatc gcagcgtggt
    21601 gattggcgtc ggcggcggcg cactactcga caccgcgaaa gccctcgccc gccgtctcgg
    21661 tctgccgttt gttgccgttc cgacgatcgc cgctacctgc gccgcctgga caccgctctc
    21721 cgtctggtat aacgatgccg gacaagcgct gcattatgag attttcgacg acgccaattt
    21781 tatggtgctg gtggaaccgg agattatcct caatgcgcca caagaatatc tactggcggg
    21841 gatcggtgac acgctggcga aatggtatga agcggtggtg ctggctccgc aaccagaaac
    21901 gttgccgcta accgtgcggc tgggaatcaa taatgcgcag gccattcgcg acgtcttgtt
    21961 aaacagtagc gaacaggcgc ttgccgatca gcaaaatcag caattaacgc aatcattttg
    22021 cgatgtggtg gatgcgatta ttgctggtgg tgggatggtc ggtggtctgg gcgatcgttt
    22081 tacgcgtgtg gcggcggccc atgccgtgca taacggtctg accgttttgc cgcaaaccga
    22141 gaagtttctc cacggcacca aagtcgccta cggaattctg gtgcaaagcg ccttgctggg
    22201 tcaggatgat gtgctggcgc aattaaccgg ggcgtatcag cgttttcatc tgccgactac
    22261 gctggcggag ctggaagtgg atatcaataa tcaggtggag atcgacaaaa tgattgccca
    22321 caccctacgt ccggtggaat ccattcatta cctgccagtc acgctgacac cagatacctt
    22381 gcgtgcagcg ttcgaaaaag tggaatcgtt taaagcctga cgtacaaatt tagcagcagc
    22441 gcgcgccgcc ttttccacca tagcgcgcgt cctgccgctc acggaaaaac tcctcgtagg
    22501 tcatcggcgt ttgatcggga tggttaaccc gcatatgttc gacatagttg tcgtaatcag
    22561 gcataccaat catcagtttc gccgcctgac ctaaatattt tccggctttt gccagtgaat
    22621 caaacatcta aacctccggt aatacaaatg ccctcctgaa ttaagagggc ttaattgcta
    22681 tcaacacgct cgggctgaga gtaaggggaa cgttcagcac atcccccctc actctgactt
    22741 tagtgcgcgc ctttcgcctg cgccacgatc tcctcgacat tttccggcat cggctcatat
    22801 ggcgtttctt tcgccgttgg cttcggctct ttcaatgccg ccagtgccgt cttaatcgag
    22861 aacagcgcca gaaccaccac gaccaccata aagaagatgg ttaacccggc atcaagacgg
    22921 ttgttgaaca ccagttgcgc cagttgtgac tcagtatact gcgatggaat attgccgctg
    22981 tcgatcattg cctggaactt gttagcaatc gccaggaatc cgactttcgc atccgggcta
    23041 aacgctttct gccagcctgc ggtcagggta caaatcagca gccaggccgt tggtaccagc
    23101 gccacccagg cgtaacgttg acgtttcatt ttgaacagca ccacagcaca aagcatcagc
    23161 gccatccctg ccagcatctg gttggcaata ccaaacagcg gccacaaggt gttaataccg
    23221 cccagcggat cgacctcgcc ctgatgcagg aagtagcccc acgccagcac gcacagcgcc
    23281 gttgccagca ggttagcagg cagtgaatcg gtccgtttca ggcccggaga caccacgccc
    23341 agcagatcct gcaacataaa gcgcgcagca cgcgtacccg catccaccgc cgtcagaata
    23401 aacagtgctt caaacagaat ggcgaagtga taccagaacg ccacatccat catgccgccc
    23461 agcgcaccgt gcagaatgta ggccatcccc accgccaggg tcggcgcacc gcccgcacgg
    23521 gaaatgatcg actgttcacc cacttcgctg gcaatctggt ttagcgtatc cggggtaatc
    23581 gcaaagcccc agctactcac cacctgcgcg gcagaagcaa ccacatccgc cgtccctgcc
    23641 ggagccagca ccgccatcgg gctgttcatg gcgaagtaca cacccggatc gatgatacag
    23701 gcggaaacca gtgccataat cgccacaaag gattccatta acatcccgcc gtagccgata
    23761 aagcacgcct gcccttcgtt cgccagcatc ttcggcgtgg tgccggaaga gatcagcgca
    23821 tggaagccag acaccgcgcc acaggcgatg gtgataaaca ggaacgggaa caggttaccg
    23881 gtccataccg ggccagtgcc atcgacaaat ttagttagcg caggcatggt cagcgtcggg
    23941 cgcataatta aaatgcccac cgccagaccg acgatagtcc cgattttcag gaaggttgag
    24001 aggtagtcac gcggagccag cagcaaccac accggcagca ccgccgccac aaaaccgtag
    24061 cccaccagca tccaggtcag ctgcacgccg gtaaagtcaa agtacggtgc ccaggtcggg
    24121 ctttctgcca cccagccgcc agagataatg gcgaaaatca ggaacaccag accaattacc
    24181 gacacttcgc caatacgccc cggacgcaaa tagcgcaggt agatccccat aaacagcgcc
    24241 agcggaatgg tgaacgcaac ggtatacgtt ccccacgggc tatgagtcag ggctttcacc
    24301 acaatcatcg ccagcacggc aaggataatg accatgatca taaagcaggc caccagcgct
    24361 atcaccccgg cggttggtcc catctcttct ttgaccagct cacccagcga gcgaccgtca
    24421 cggcgcgtag aaacaaacag caccatgaaa tcctgcaccg caccggcgag aaccaccccg
    24481 gcgagcagcc agatcatccc tggcaggtaa cccatttgcg ccgccagtac cggcccaacc
    24541 aacggacctg ctccggcaat ggccgcaaaa tggtgaccga acagcacttt tttgtccgtc
    24601 ggcacatagt ccagcccgtc gttatggcgc accgctggcg tcatacgcgt cgggtcaacc
    24661 gccagcacat ttttggcgat atacaggcca taaaaacggt aggcgattag atagatacag
    24721 accgacgcca ccacaatcca cagcgcgttg atctgttccc cacgatttaa agcaatgtat
    24781 cccagagcaa atgctcccat tacagcgagc actgtccaga cgaggtattt ccctgatttg
    24841 ttcatagttg ttatccgtgt gcgtgtccat agagatgtta cattttgttt ctataacatc
    24901 tttgtacaat ttaacaacac agcaaccatg taaatcggaa ttgaaaccaa tatttaactt
    24961 aacaatgtta actcgatcac tccgttaacc gagttttcct gcaatctcat ttaattctgt
    25021 cgggctcatc ccaaaactgc cgtacccagc cgacaggtgc agcagcgccg cccctgttca
    25081 tcgaaaacga caatttccca gctctgattt tgtcgtccaa gatgcagcgg ctggcagaca
    25141 ccgcgcacct ttccctcaga caccgggcga tgatgtgtgg cgttaagttc cgtgcccacc
    25201 acacactgtc cgtcgcgggt catcataaat ccggccatcg atcccagcgt ttccgccagc
    25261 gccgccgacg cgccgccatg cagcaggcca aacggctgat gagtacgggt atcaaccggc
    25321 atttcggctt cgagtacatc atcgcccaga cgggtataca caattcccag atgcgccacc
    25381 attgtgttat cgctggtggc gttcagctcg tcgagcgtta aatgacgttt ccagatcatg
    25441 cttatgcccc cagcgttgag ccgccatcga ccacaatatc ctgtagggta atatggctgg
    25501 cgaggtcaga ggcgaggaac aaaatcgtgt tggcgatctc ttgtggacag gcgattttcc
    25561 ctagcggaat gccgagttta aactgctcgc caaagccgcg aatacgctgc tcttcggcgt
    25621 catcgctcac ccacagcgtg cgttgcatat cggtgtcggt ggagcccggc gaaaccacat
    25681 tacagcgcac gccgctaccc gccagttcca gcccgacgct caacgccagg cttttcagcg
    25741 ccgctttcga cgcgccataa gcactcatac caatacgcgg cgtgtgtgcg gcgtcggacg
    25801 caacagtaac aatcgccccg ccccgctgac ggcgaaactg gttcatggtc tgctgaaaca
    25861 ggttaaacgc accgccgacg ttgaccgcaa aagtctgctg ccagtcctct ttactgagct
    25921 gatcggtcgc gcccatgcgc aaaattcccg ccgcattgac cagcacgtcc agtcgctccg
    25981 tttcagctaa cagtcgctga catacctgcg ccacctgcgc agcatcggca acatccatta
    26041 cttcggtcgc aaaaggatat tgctcctgac taaacgcttg atcaaaacct gtaactttcg
    26101 cccccgcctc aacaaatgcc agcgccgtgg cgtagcctat acctttcccc gcgccagtta
    26161 cccagacatt tttaccgctg aaatccatta tttcacctcg cgggagagta gcttccacca
    26221 ggcgtcgatg gtcgggtttt tcgccagcat gacaaagtcg atatcgccat gcactttgcg
    26281 ccagcgcgcc gccagcgcca tcatgcgcac cgaatccaga ccgtagtcga tcaggttgtc
    26341 gtcatcgaag ggttcatcgg actcgtccag caacggcagg atcacctcac gcagcgccgc
    26401 tttgctggcg gggataggtg ctggcagcaa ttcttcggtc atcaccaccc gaccagaacg
    26461 tccggccaca tatttcagcg acatcaaatg ctcgtcacgg ctgaaatcgg ccagcgcatc
    26521 cgccaccata aacggtttaa tatcgcgcat aaatgcgtcc gttgcggtgg tcatacagcc
    26581 aatgtgggca tataccccgg taataatcag ctggttacgt ccactctctt tgagcatttg
    26641 ctccagcgga gaacgatgaa atgcgctgta gcgccatttc accagcaccg tgtcgtcggc
    26701 atctggcgtc aggcgatcca ccaccttttg ctgttccggc gaacgggtca ggccaggccc
    26761 ccacatatca ttcaacagcg cccgatcttc atcgctctgc tctttcggct gggcggtgta
    26821 ataaaccggg atattgtgct gtttgcagta gtcgcgtagt gccgcaatat tcgcgatcac
    26881 ctgctccatc atcgggcagt tctcacccca gaagctgaca aaatagtcct gcatatcatg
    26941 gattaacaac gcggcacgtt gcggttcaaa ggcccagtcg actttattct gcggaatatc
    27001 gtgaggctcc ggcagtgcgt aagcctgtaa ttttggaata gccatcgtgt tctctccttc
    27061 aggctgatgt gcgtgacgcc agccactgac gtaattgttt tttatcgact ttcccgaccg
    27121 ccgtcagcgg aagtgaatct acacactcca cgcgatccgg taatttaaat tcggcaatac
    27181 cctgttcacg caggaaacga cgcacctgca ccgcgcgcag cggctctttt accaccagat
    27241 aagcacagct tttttcgccc atcagctcat cttccatgct caccagtgcg gcgtagatca
    27301 ccgccggatg gcgcagcagc aggttttcga tctcttcggc agcgatcttc tcgccgccac
    27361 ggttgatctg atctttctcg cgcccctgca cagtgatgta accctctgga tcaatagaga
    27421 tcagatcgcc ggaacagtaa aaaccgttgg catcaaaggc gctggcattg tgctgcgggc
    27481 ttttgtaata gccacggaaa gtgtacggcc cgcgcgtcat caggcgtcca acttcccctt
    27541 gcggcagtgg atttccttcg gcatcggcaa cccatacttc atcgtccggg cacattgggt
    27601 aaccctgggt atggataatt ttctccgcac tatcatcaag acgggtgtag ttcaccagcc
    27661 cttccgccat gccaaacacc tgctgcaact ggcagccaat ctcagcggga atacgcgccg
    27721 caagcgtggc agaaagacgt gcgccgccga cctgtaacag tttcagcgag gcaagctgcg
    27781 cccggctttc gccttcagcc agtgcctgca accacaggct gactgctggc ggcaccagcg
    27841 cggtgacgtt cacctgatgt ttttcaatca atgggaagca aagcgtggcg ctggggtcgg
    27901 cagccagaac gacagtgccg ccagcgagaa atacccccaa cgatcccggt gaactcatgg
    27961 cgtagttatg agccgccggg atcgcgcaca ggtagcgcgt ctgttgtgtg aactgacaaa
    28021 tctcgacgct acgacgcacg ctgtagtagt agtcgttatg agtgcgcggg atcagtttcg
    28081 gagtgccggt ggtgccgccg gaaagctgga aataggccac ttcatcagca ggagatggcg
    28141 tggcagtaaa atcctcagcc ggatggttaa tcgcatcctg caagttatgc tcaccgctgt
    28201 cgttgagcag ctgcaccacg cgaatggaag aatgctctgc aacaaatgtg ttgaggaaat
    28261 catccccgct aaatagcgca tgttggcgat cggcaatcag taacgccggt tcaatctggc
    28321 tggcataggc gttcagttca ctacgctgat ggctgaacag cgccagcacc ggcgcaacgc
    28381 ccagtttcag cagcgcgaaa aaggtaatgt aaagttcagc gacgttaccc agttgtacca
    28441 gcgcggtttc accaggttta atgccctgac ggcgcaaact acaggcgagg ttatccgccg
    28501 cctgattcag ctcccggtaa ctcaactgcc actcgccgtc gatcaccgcg atgctgtcac
    28561 tcgcagcgtg gcgagtcaga atgtcggtca gtggcaaatc ctgccagtag cctttttccc
    28621 gatagcgacg ggcaaactct tccggccatc gggtgaatgg aatgctcatc ctcgctcctt
    28681 aatgcaatcc aaaaacgttc aacatggtag aaagtttgac gcctgtttcg cgccactcac
    28741 ccaacggtga ggacgcaggc acaatccccg ctccggcaaa cagacgcacc tgattttccc
    28801 gcagcttcgc gcagcggatg gtcaccaccc attcaccgtt accttcgctg tcacaccaac
    28861 ccacaatgcc gccaaacagt tcgcggtcga acggctccag ttcagcaata acctgagtcg
    28921 cggccagatg cgggaaaccg ctcagcgcag gagttggatg cagcagacag gccagagtca
    28981 gtgcgttttc ttgcgaattc gctttacctt caaagggagt tgcgagatgc cacagcgtcg
    29041 gcgtggtaat caattgtgga gaggagggaa cgtgtaactc actactgcgt tcgcgcagta
    29101 cctctttcat cgcctgagtc accagttcat gttcatggcg atctttttct gacgccagca
    29161 gacgattacc cgcttcgcga tcgagcactt catctggctg acgacgcgcg gaaccggcta
    29221 acggaatgga gctaaaacgc tcgccgtctt tacgtagcag cagttccggg ctggccccca
    29281 gcagaacgcc accatcagcc aacggaacat ggaagttgta actaaccggg ttttgcgcaa
    29341 tcaaccgttc cagcaatacg ccactatcaa tggcggcgtc agtggtgata tcaatcaacc
    29401 gtgacaacac cactttgtcg acctgcggcg tggcggtaag tgcggcagca cgggcaacca
    29461 tctgttcaaa cgtggtttgt tccggaatgg cctgacgttc caccacgttc agcgactggc
    29521 tgcgggtgaa acggcgtgcg gaagcttgtt tttcctgacg ggagaacgac tgccaggatt
    29581 cgggaatata cagcgacgaa ggctgacgtg gatcgaaggg aatcgccccg accatcaccg
    29641 gatttttgat gccctgcgct ttggcatcgg caaacagcgc ggcgagtttt tgctggaagg
    29701 gactgtcggg tgaatccccg ttcacagcgg gttcatcgaa gcgggcgaaa catcctgacg
    29761 tcgtaaaact gcggtacggc gacataaaga aaaagcgatt gggcgcaagt gttgccatgg
    29821 tctgctgtac ttcctcagcc agtgacgtat ccatatcatc ctccacaaaa tgataaaggc
    29881 tttaataatg attatcattt atattttcgg tcgctaacct aaaagcaaac gcgcactatg
    29941 tcaactcttg aggtaacgca atctgcaact cggggttgca tctggttgtg gttacaatga
    30001 aaatgagaag cattaacttc attaataaca ggaagctgat ttgtgagact cgcctcgctc
    30061 taccgcaacg cccttctatt aacaggactt ttgctttcag gaatagccgc agttcaggcc
    30121 gccgactggc cgcgtcagat tactgacagc cgtggcactc ataccctgga aagccagccg
    30181 cagcgtattg tatccaccag cgtcaccctg actggctcac tgctggcgat tgatgctccg
    30241 gtgatcgcca gcggcgcgac cacaccaaat aaccgcgtag cggatgacca gggcttttta
    30301 cgccagtgga gcaaggtggc gaaagaacgc aaactgcaac ggctctatat cggcgaaccg
    30361 agtgcagaag ccgttgccgc gcaaatgccg gatctgattt taattagcgc aaccggcggc
    30421 gattcggcgc tggcgctgta cgatcagctt tctaccatcg ccccaacatt aatcatcaat
    30481 tacgacgaca aaagctggca gtcgctgtta acgcagcttg gcgaaattac cgggcatgag
    30541 aaacaagcgg cagagcggat tgcactgttt gataagcaac tggcagcggc gaaagagcaa
    30601 atcaaattac cgccgcagcc ggtcactgcc cttgtctata ccgccgctgc acacagtgcc
    30661 aatctctgga cgccggaatc agcacaaggg cagatgctgg aacaactcgg ctttacgctg
    30721 gcgaagttgc ccgcaggctt aaacgccagc caaagccagg gcaaacgcca tgacatcatt
    30781 cagcttggtg gagaaaatct ggctgcaggg ttaaatggcg agtcactatt cctgttcgcc
    30841 ggtgatcaga aagacgccga tgctatttat gctaatccgc tgctcgcgca cctgcctgca
    30901 gtacaaaaca agcaggttta tgcgctggga accgagacat tccgcctgga ttactacagc
    30961 gccatgcaag tgctggaacg acttaaggcg ctgttttaag cattaattgt cggacgctgt
    31021 cacctgcggc ggcgtctggc gaaaacgccg caactccacc agcaccagca acaacaacac
    31081 gccgataatc aacaaaccaa aaccgctcgc gcttgcggaa gcaaccggtg tcatcatcgc
    31141 tcccagaccg cctaacagcg ccgcacctat ggcatcgccc gtcacgtttt gcgccgtcca
    31201 caaaccgtta atccgcccta acatcgcttc cggggtttgc gtttgcagca ttgtatattg
    31261 cagcaacgaa ctaaccgcgc tcagccagcc gaacagtgcc agacaaacca cgcctaaaat
    31321 ccacatcggc atcaggccaa acagaccaat ggcgaggaac gcccccaatg tggagagcaa
    31381 catcaacaga cctggccgta cgctatgcgc cagttttcca ctggttaacg cgccaatagc
    31441 cgcaccgagc gggattgccg catagagaaa gccaatttgc gccgccgaca tctgccagtt
    31501 gtcagccagc gccggataca gtacccgcac cgcgctcgcc atcgtcaata aaccccccag
    31561 caacgcaatc cctcccacca gcgggctggc gagtagaaaa cgaaatcctg ccagtaatga
    31621 tttcaacgga tgctcacgcg gctgcggcgg tggtggcaac gccggaaggc ttaacaacgg
    31681 tagcaaggta ataaacgtgc ccgccgccgc cagcccgtag ttccaggcta cgcctccggt
    31741 cgccagcagt aaaccaccaa tcatgggcga aatcaccgac cccagacgca cagtcaacat
    31801 ggtgatcgcc ccggcctgca ttaggttttc acgtcctacc agtgcaggtg tcgccgccag
    31861 tagcgccgta acgccaagtg atgcgaaaaa accatcccat aaaccaagta aatagattgc
    31921 cagcaaagac ggctccggca gcagcgcatt caggcacagt ccaatgaagc caatgccaca
    31981 ggtgccgcgc gccagcaaaa tcactttttt gcgctcatag cgatccgcca gcacaccacc
    32041 gatcatcaga ccgacaaaca tagcaccgcc ggtcagcgtc accgaaagcc ccacctgcca
    32101 ggtagaatgt gtcatcatct ggatctgcac cggcaccgcg acgctgagca aacccagaga
    32161 cacaattgag ataaaacgag cgaggaatac tgcgcgaaac gccgggtgcg tttttaacag
    32221 gctgaggtta agcagccagg attgtttatt cattacaatg ccttgccatc aaatatttta
    32281 aatacctatt cttaggctgc acatgctaac atatccaaat aagatcgata acgataatta
    32341 atttcattat catggaagtt cgtatgtctg gttctgttgc cgtgacacgc gccattgccg
    32401 tgcccggatt gctgttatta ctgattatcg cgacggcatt aagcctgctc attggagcaa
    32461 aatcactccc cgcttccgta gtgctggaag ccctctccgg cacctgccag agcgccgact
    32521 gcaccatcgt gctcgacgca cgactgccgc gcacccttgc cggtttactg gcaggcggtg
    32581 cgcttggcct tgccggggcg ttaatgcaaa ccctcacccg aaacccactt gccgaccccg
    32641 gcttgcttgg cgtgaatgcc ggagccagct ttgccattgt gctgggtgcg gcgctgtttg
    32701 gttactcttc cgcgcaggaa caactgatga tggccttcgc cggcgcgctg gtggcgtcat
    32761 tgattgttgc ctttaccggc agccagggcg gcgggcagtt aagtccggtg cgtttaaccc
    32821 tggcgggcgt ggcgctggcg gcggtgctgg aaggactgac cagcggcatc gccctgctta
    32881 atcctgacgt ctacgatcaa ctgcgtttct ggcaagccgg ttcgctggat attcgcaatc
    32941 tacatacctt aaaagtggtg ctgatcccgg tgcttaccgc cggagcaacc gcgctattac
    33001 tgagccgcgc gctgaacagt ttaagccttg gcagtgacac cgcgacggcg ctgggcagtc
    33061 gcgtagcgcg cacacagttg attggtctgc tggcaattac cgtgctttgt ggtagtgcaa
    33121 cggcggtagt tggcccgatt gcctttattg gcctgatgat gccgcacatg gcgcgctggc
    33181 tggtaggtgc cgatcatcgc tggtcgctgc ccgtcacgct actcgctacc cctgccctgc
    33241 tgctgtttgc cgatatcatt gggcgggtga ttgttcccgg cgaactgcgc gtttctgtag
    33301 tcagtgcctt tattggtgca ccagtgctga tcttcctcgt acgacgtaaa acgcgaggtg
    33361 gcgcatgatt tacgtctctc gccgattaat tatcacctgt ctactgttgc taatagcttg
    33421 tgtaatggca ggcgtgtggg gattacgcag cggtgccgtc acgctggaaa cctcgcaggt
    33481 attcgccgcg ctgatgggcg atgcgccgcg cagtatgacg atggtggtca ccgaatggcg
    33541 tttaccacgc gtgctgatgg cgctgttgat tggcgcggcg ctgggcgtca gcggcgcgat
    33601 ttttcagtcg ctgatgcgta acccgctcgg cagccctgac gtaatgggct ttaacaccgg
    33661 ggcgtggagc ggcgtgctgg tggcgatggt gctgtttggt caggatctga cggctatcgc
    33721 gctggcagca atggcggggg gtattgtcac ctcgctgctg gtctggctgc tcgcctggcg
    33781 taacggtatc gacacctttc ggttgattat tatcggtatc ggcgttcgcg ccatgctggt
    33841 ggcctttaat acctggctgt tgctgaaagc gtctttagaa acggcgctaa cagcgggttt
    33901 gtggaatgcc ggatcgctca atggcctgac gtgggcaaaa acctcacctt ccgcacccat
    33961 cattatatta atgttaattg ccgccgcctt gctggtgcgg cgaatgcgct tgctggaaat
    34021 gggcgatgat accgcgtgtg cgctgggcgt cagcgtcgaa cgttcgcggc tgttaatgat
    34081 gctggtcgcc gtagtgctta ccgcagctgc cactgccctg gcggggccaa tttcctttat
    34141 tgctttagtc gcgccacaca ttgcccgccg catcagtggc accgctcgct gggggctgac
    34201 ccaggcggcg ctgtgcgggg cacttttact gctggcggcc gatctctgcg cccaacaact
    34261 gtttatgccg tatcaacttc cggttggcgt cgttaccgtc agcctcggcg gtatttacct
    34321 tatcgtcttg ttaattcagg agtctcgcaa aaaatgaccg aatcagtagc ccgtttgcgt
    34381 ggcgaacagt taaccctcgg atatggcaaa tataccgttg cggaaaatct gactgtagaa
    34441 atacctgatg gtcacttcac ggcaattatc gggccaaatg gctgcggtaa atccacgtta
    34501 ctgcgtacct taagccgcct gatgacgcct gctcacgggc atgtctggct ggatggcgag
    34561 cacattcaac attacgccag taaagaggtt gcacgccgga ttggtctgtt ggcgcaaaat
    34621 gctaccacac cgggcgatat caccgtgcag gagctggtgg cgcgtgggcg ttacccgcat
    34681 caaccgctgt ttacccgctg gcgcaaagaa gatgaagacg cggtaacaaa agcgatgcag
    34741 gccacgggaa taactcatct ggcggatcaa agcgtggaca ccctttctgg cggacaacgc
    34801 cagcgagcgt ggatcgcgat ggtgctggcc caggaaacgg caattatgct gctcgacgaa
    34861 cccacgacct ggctggatat cagtcatcag attgatctac tggaactgtt aagcgaactg
    34921 aaccgcgaga aaggctatac cctggcggcg gtgctgcacg atcttaatca ggcctgtcgt
    34981 tacgccagcc atttgattgc attgcgggaa gggaaaattg ttgctcaggg agcgccgaaa
    35041 gagattgtca ctgctgaact gatcgagcgc atttatggtc tgcgctgcat gataattgac
    35101 gatccggttg ccggaacgcc gctcgtggtg ccgctcggac gaacggcacc ttcaaccgca
    35161 aagatttaaa ctaagtggtc tgccatcatg gcatcctgtt ttctggatgc catcgcatga
    35221 cgcaacaaca caccaccaca agccaccatc ccgccgacca acgcagaaag gatcacgata
    35281 atcgccttac cctgaccgtc tttttttacg ggtaatgacg gacgcaactg atatttaaac
    35341 ggtgtaaaat tcacatcgtt gacatttgtt tttgttaatt gctcgactag atactgacga
    35401 ttacgtaatt caccgttcaa ttccgcaacg tcagtgactg ctttttcaat ttccagtttg
    35461 cgttcaatac cgtctgcacc gagagaaata gagaaatcgg ggtcatcttt aacggcctga
    35521 ccattactgt atacgggctt tttaattcct gccgcgttgg caatgtcaag tgaataattg
    35581 aggcgctgaa tgtttgcatc aagttgattt ttcgttttaa tgcgatcctg agccagtttt
    35641 tctttttcaa actgggtttt gatctccagt ttattacgga cgttttctat cgactctttc
    35701 accaccaacg cagagatata atcgatatac ccggccaaca ctttctgtgc ctcttcactg
    35761 gtgggtgcgg tgaaacttag cgtccaggaa gtatacaatg cagactcatc ttttttctta
    35821 ctggcattgt catcaaccgc tttcattttt tcgctcaatg caacaatggc gcgatgcaga
    35881 tccagtgggt cgattttcgc ttcttttaat tgatccatca cataaggtga tgaacgcagg
    35941 tactcctcaa gcaagctaac agactgaaat ttcttgataa acaggttaaa tgcttctgta
    36001 cgatcaattt tgatatccag atccagcaca cgaagcttag tgaatgtttt ctccagctct
    36061 tgccactgaa caggttctgg aggcgtgaca accgccgcgc tagtccattt ttgcggcagg
    36121 atgaaagaga tcagcaagcc tgcgcaggca aacgcaaaaa cgaccgccat gaccgttttt
    36181 tttgcccgcc ataaaacctc gattagatta agtaaatcaa tttcattatt actgggcgac
    36241 gccagaggat actcgggaaa atgagcttca cttccctgtt taatattcag tgatgacatg
    36301 tagtgaaacc tgaggtttta gtccgtaaag cacaacgatg tacatagcat tctaacagga
    36361 actgagattt atccgaaagc actctttcac tattattatt ctcaaaatga ataaca
//
LOCUS       DAPOXO010000048        36282 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPOXO010000048 DAPOXO010000000
VERSION     DAPOXO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36282
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.048"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(61..1023)
                     /gene="ldtC"
                     /locus_tag="ROH59_002798"
     CDS             complement(61..1023)
                     /gene="ldtC"
                     /locus_tag="ROH59_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HDX4805257.1"
                     /translation="MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPSAGSRLVGEN
                     KFHVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPRE
                     GIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTAN
                     IRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCI
                     RLRDDDIKTLFSQVTPGTKVNIINTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPI
                     TLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(1166..4612)
                     /gene="mfd"
                     /locus_tag="ROH59_002799"
     CDS             complement(1166..4612)
                     /gene="mfd"
                     /locus_tag="ROH59_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDX4805258.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPSMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLENSAERFQADTLARFENRGIDPMRPLLPPQSLWLRVDELFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAIQAQQKAPLDALRKFLESFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLL
                     GERVARRRQDSRRAINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFMAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
     gene            complement(4739..5812)
                     /locus_tag="ROH59_002800"
     CDS             complement(4739..5812)
                     /locus_tag="ROH59_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HDX4805259.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASTSLWYLYALIVYFVICKIF
                     NPLALPLFVLFVLMSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATLMTCVKAVPLR
                     RHLLMASLLTVLAVGAWLFNISLLLSLVSIVVIMKLFYQYEQRFGMRSSSLLNVIGSN
                     TIAIYTTHRILVEIFSLSLIPQMNAVRWSPQVELTLLLIYPFVSLLICTVAGLLVRKL
                     SQRAFSDLLFSPPSLPATVSYSR"
     gene            6073..7272
                     /gene="lolC"
                     /locus_tag="ROH59_002801"
     CDS             6073..7272
                     /gene="lolC"
                     /locus_tag="ROH59_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HDX4805260.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            7265..7966
                     /gene="lolD"
                     /locus_tag="ROH59_002802"
     CDS             7265..7966
                     /gene="lolD"
                     /locus_tag="ROH59_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309522.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HDX4805261.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLEHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            7966..9210
                     /gene="lolE"
                     /locus_tag="ROH59_002803"
     CDS             7966..9210
                     /gene="lolE"
                     /locus_tag="ROH59_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HDX4805262.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDNVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVNPQQEQRLSALPSFVQDDAWSNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            9239..10150
                     /gene="nagK"
                     /locus_tag="ROH59_002804"
     CDS             9239..10150
                     /gene="nagK"
                     /locus_tag="ROH59_002804"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDX4805263.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLAERLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            10166..10987
                     /gene="cobB"
                     /locus_tag="ROH59_002805"
     CDS             10166..10987
                     /gene="cobB"
                     /locus_tag="ROH59_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDX4805264.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQTFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL"
     gene            complement(11125..11913)
                     /locus_tag="ROH59_002806"
     CDS             complement(11125..11913)
                     /locus_tag="ROH59_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDX4805265.1"
                     /translation="MKKIIILLSLLILLPLTATSKPLIPIMKTLFTDVTGTVPDAEEI
                     AHKAELFRQQTGVAPFIVVLPDINNEASLRQNGKAMLAHAASSMSNVKGSVLLLFTTR
                     EPRLIMITNGQVESGLDDKHLGLLVENHTLAYLHADLWYQGINNALAVLQAQILKQPT
                     PPLTYYPHPGQQHENDPPGSTTTLGLFAWAVAFIVFAAFFNYTTRLYYALKFAVAMAV
                     ANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLWTSKR"
     gene            complement(11910..12371)
                     /locus_tag="ROH59_002807"
     CDS             complement(11910..12371)
                     /locus_tag="ROH59_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HDX4805266.1"
                     /translation="MSQDSRVFFRIFFGIGLVLILISVVIFYNQFTYSKDAIHTEGVI
                     VDTVWHSSHSHRTGKNGSWYPVVAFRPTPDYTLIFNSSIGSDFYEGSEGDKVNVYYSP
                     GHPEKAEINNPWVNFFKWGFIGIMGVIFISVGLLISMPSSKKTRRKRKSRP"
     gene            complement(12429..13475)
                     /gene="potD"
                     /locus_tag="ROH59_002808"
     CDS             complement(12429..13475)
                     /gene="potD"
                     /locus_tag="ROH59_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HDX4805267.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLSNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAAS
                     SIYEEYYQKLKAGR"
     gene            complement(13472..14266)
                     /gene="potC"
                     /locus_tag="ROH59_002809"
     CDS             complement(13472..14266)
                     /gene="potC"
                     /locus_tag="ROH59_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HDX4805268.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            complement(14263..15120)
                     /gene="potB"
                     /locus_tag="ROH59_002810"
     CDS             complement(14263..15120)
                     /gene="potB"
                     /locus_tag="ROH59_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HDX4805269.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFIFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKVELE"
     gene            complement(15104..16240)
                     /gene="potA"
                     /locus_tag="ROH59_002811"
     CDS             complement(15104..16240)
                     /gene="potA"
                     /locus_tag="ROH59_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HDX4805270.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            16490..17716
                     /gene="pepT"
                     /locus_tag="ROH59_002812"
     CDS             16490..17716
                     /gene="pepT"
                     /locus_tag="ROH59_002812"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDX4805271.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRK"
     gene            complement(17765..18886)
                     /gene="roxA"
                     /locus_tag="ROH59_002813"
                     /gene_synonym="ycfD"
     CDS             complement(17765..18886)
                     /gene="roxA"
                     /locus_tag="ROH59_002813"
                     /gene_synonym="ycfD"
                     /EC_number="1.14.11.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309600.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[50S ribosomal protein L16]-arginine
                     3-hydroxylase"
                     /protein_id="HDX4805272.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGDVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(18962..20422)
                     /gene="phoQ"
                     /locus_tag="ROH59_002814"
     CDS             complement(18962..20422)
                     /gene="phoQ"
                     /locus_tag="ROH59_002814"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HDX4805273.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE"
     gene            complement(20422..21093)
                     /gene="phoP"
                     /locus_tag="ROH59_002815"
     CDS             complement(20422..21093)
                     /gene="phoP"
                     /locus_tag="ROH59_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HDX4805274.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHL
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            complement(21262..22632)
                     /gene="purB"
                     /locus_tag="ROH59_002816"
     CDS             complement(21262..22632)
                     /gene="purB"
                     /locus_tag="ROH59_002816"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDX4805275.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVADIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNHDHLLEELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            complement(22636..23277)
                     /gene="hflD"
                     /locus_tag="ROH59_002817"
     CDS             complement(22636..23277)
                     /gene="hflD"
                     /locus_tag="ROH59_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HDX4805276.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDGDALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            complement(23313..24419)
                     /gene="mnmA"
                     /locus_tag="ROH59_002818"
     CDS             complement(23313..24419)
                     /gene="mnmA"
                     /locus_tag="ROH59_002818"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDX4805277.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGTEEPWYVVDKDVENNILIVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            complement(24473..24934)
                     /gene="nudJ"
                     /locus_tag="ROH59_002819"
     CDS             complement(24473..24934)
                     /gene="nudJ"
                     /locus_tag="ROH59_002819"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HDX4805278.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            complement(24944..25597)
                     /gene="rluE"
                     /locus_tag="ROH59_002820"
     CDS             complement(24944..25597)
                     /gene="rluE"
                     /locus_tag="ROH59_002820"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415653.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HDX4805279.1"
                     /translation="MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPDNQPTRVILF
                     NKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPG
                     KRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVEEPAWLWPRNPPIRER
                     KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWRDATD"
     gene            25769..27019
                     /gene="icd"
                     /locus_tag="ROH59_002821"
     CDS             25769..27019
                     /gene="icd"
                     /locus_tag="ROH59_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HDX4805280.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGDAIIKNM"
     gene            complement(27133..28275)
                     /locus_tag="ROH59_002822"
     CDS             complement(27133..28275)
                     /locus_tag="ROH59_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HDX4805281.1"
                     /translation="MAARPRSHKISIPNLYCKLDKRTGKVYWQYKHPLSGRFHSLGTD
                     ENEAKQVATEANTIIAEQRTRQILSVNERLERMKGRRSDITVTEWLDKYISIQEDRLQ
                     HNELRPNSYRQKGKPIRLFREHCGMQHLKDITALDIAEIIDAVKAEGHNRMAQVVRMV
                     LIDVFKEAQHAGHVPPGFNPAQATKQPRNRVNRQRLSLPEWQAIFDSVSRRQPYLKCG
                     MLLALVTGQRLGDICNLKFSDIWDDMLHITQEKTGSKLAIPLNLKCDALNITLREVIS
                     QCRDAVVSKYLVHYRHTTSQANRGDQVSANTLTTAFKKAREKCGIKWEQGTAPTFHEQ
                     RSLSERLYREQGLDTQKLLGHKSRKMTDRYNDDRGKDWIIVDIKTA"
     gene            complement(28265..28501)
                     /locus_tag="ROH59_002823"
     CDS             complement(28265..28501)
                     /locus_tag="ROH59_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDX4805282.1"
                     /translation="MSRLITLQDWAKEEFGDLAPSERVLKKYAQGKMMAPPAIKVGRY
                     WMIDRNSRFVGTLAEPQLPINANPKLQRIIADGC"
     gene            complement(28641..28880)
                     /locus_tag="ROH59_002824"
     CDS             complement(28641..28880)
                     /locus_tag="ROH59_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HDX4805283.1"
                     /translation="MFRVIDPNTWYVDHHGTPCKILRSTHNKVHYIRKGRTCIASMFR
                     FNHDFEPVNKADADRIAEEIETAEHIKKLRDMRRK"
     gene            complement(28864..29190)
                     /locus_tag="ROH59_002825"
     CDS             complement(28864..29190)
                     /locus_tag="ROH59_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDX4805284.1"
                     /translation="MANLQLAVKSEYFDAMIRGEKTEEYRLCNDYWNKRIMFREYDRL
                     IITKGYPKRDDSSRRIDVPYDGYEVKTITHPHFGDKPVKVFAIKVNISTEYQSAQHKV
                     KNVQSD"
     gene            complement(29190..29411)
                     /locus_tag="ROH59_002826"
     CDS             complement(29190..29411)
                     /locus_tag="ROH59_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDX4805285.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRLNYLAVSATHCCECGDPIDE
                     RRRLAVQGCRTCASCQQDLELIRKQRGIK"
     gene            complement(29510..29791)
                     /locus_tag="ROH59_002827"
     CDS             complement(29510..29791)
                     /locus_tag="ROH59_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDX4805286.1"
                     /translation="MHFSGSGLHILCAYACRHGACSVTPQQENALRSIARQANSEIKK
                     VRQQFPDKNVNDICRSVLKKHRETVTLKGFTPTHLSLAIGMLNGVFKER"
     gene            complement(29802..29993)
                     /locus_tag="ROH59_002828"
     CDS             complement(29802..29993)
                     /locus_tag="ROH59_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="HDX4805287.1"
                     /translation="MHKASPVELRTSIDLAHSLAQIGVRFVPIPAETDEEFHTLATSL
                     SQKLEMMVAKAEADERDQV"
     gene            complement(29966..30148)
                     /locus_tag="ROH59_002829"
     CDS             complement(29966..30148)
                     /locus_tag="ROH59_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 domain-containing protein"
                     /protein_id="HDX4805288.1"
                     /translation="MTHPHDNIRVGAITFVYSVTKRGWVFHGLSVIRNPLKAQRLAEE
                     INNKRGAVCTKHLLLS"
     gene            complement(30145..30825)
                     /locus_tag="ROH59_002830"
     CDS             complement(30145..30825)
                     /locus_tag="ROH59_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HDX4805289.1"
                     /translation="MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKP
                     RSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTE
                     SPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
                     SMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMASFDEMVPEFIEKMDEALAEIG
                     FVFGEQWR"
     gene            complement(30822..31607)
                     /gene="bet"
                     /locus_tag="ROH59_002831"
     CDS             complement(30822..31607)
                     /gene="bet"
                     /locus_tag="ROH59_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HDX4805290.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDD
                     DLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA"
     gene            complement(31613..31909)
                     /locus_tag="ROH59_002832"
     CDS             complement(31613..31909)
                     /locus_tag="ROH59_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor protein Gam"
                     /protein_id="HDX4805291.1"
                     /translation="MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLF
                     ESLCIDHLQRCGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHHVDIDSEV"
     gene            complement(31985..32191)
                     /locus_tag="ROH59_002833"
     CDS             complement(31985..32191)
                     /locus_tag="ROH59_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor protein"
                     /protein_id="HDX4805292.1"
                     /translation="MVHQHYGTQTVNRGAVMPGMLVKHKDGTWTASANLRGRLYLHRG
                     IERTYTRDLLVEVFLDGRGNGLNH"
     gene            complement(32787..33476)
                     /locus_tag="ROH59_002834"
     CDS             complement(32787..33476)
                     /locus_tag="ROH59_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4805293.1"
                     /translation="MKTTLSERLKEARLARGLTQKALGDLVGVSQAAIQKIETGKANQ
                     TTKIVEIANALGVRAEWLSSGVGNMSDSTVQPIQSTVSHSKYFKIDVLDIEVSAGPGV
                     INREFVEVLRSVEYSFDDARHMFDGRKAENIRIINVRGDSMSGTIEPGDLLFVDITVK
                     SFDGDGIYAFLYDDTAHVKRLQMMKDKLLVISDNKSYSPWDPIEKDEMNRVFIFGKVI
                     GSMPQTYRKHG"
     gene            33581..33811
                     /locus_tag="ROH59_002835"
     CDS             33581..33811
                     /locus_tag="ROH59_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4805294.1"
                     /translation="MNPAIKTAINIVGSQKKLGAACEVSQQAVYKWLHNKAKVSPEHV
                     GSIVTATGGVVKAYQIRPDLPKLFPHTEKNAA"
     gene            33881..34420
                     /locus_tag="ROH59_002836"
     CDS             33881..34420
                     /locus_tag="ROH59_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT domain-containing protein"
                     /protein_id="HDX4805295.1"
                     /translation="MQPLTYQQTSGFSPTAVINRSQTKQVPGHEKIRDAVRAWSAVDN
                     QDVVATLIVNEYLEQGGGTIDFPDDVSRARQKLFRFLDNKFDSEKYRNNVRELTPAIL
                     AVLPLEYRGYLVEQDSFMARLAEMEKELSEAKQAVILNAPRHQKLKEISEGIVSMFRV
                     DPDLAGPLMAMVTTMLGAI"
     gene            34417..35436
                     /locus_tag="ROH59_002837"
     CDS             34417..35436
                     /locus_tag="ROH59_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDX4805296.1"
                     /translation="MTGSEMAKAGLLEQNRLSGANRNTLIAGGIMANTAEIFNFPVPD
                     AAQKEPRVADLDDGYTRIANELLEAVMLAGLTQHQLLVFLAVMRKTYGFNKKLDWVSN
                     EQLSELTGILPHKCSAAKSVLVKRGIFIQSGRNTGINNVVSEWSTLPESGKKNKVYLK
                     EVNLPESGKKSLPKSGKGVYPNQVNTKDKLTKDNIKPFSSENSGESSDQPENDLPVVK
                     PDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLMRERDGRNHR
                     DMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQAGVTASKPKLDLTNTDWI
                     YGVDL"
     gene            35433..36134
                     /locus_tag="ROH59_002838"
     CDS             35433..36134
                     /locus_tag="ROH59_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein P"
                     /protein_id="HDX4805297.1"
                     /translation="MKNIAAQMINFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVF
                     SQLLATFPASLANRDQNELNEIRRQWVLAFRENGITTMEQVSDGMRVARRQNRPFLPS
                     PGQFVAWCREEASVTAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
                     YQNMRANALTDAELRRKAADELACMTARINRGEAIPEPVKQLPVMGGRPLNRAQALAK
                     IAEIKAKFGLKGAMK"
BASE COUNT         8901 a         9052 c         9234 g         9095 t
ORIGIN      
        1 gctactgctt gtttttttcc ccgcgacatg ccgtgtcgcg gggatttttt tatccgagct
       61 ttacagagtt tgtgggctca cttgatgacg gcggacatcc accggcatcc cggaacggac
      121 atccatcaca tgttgcatca cttcagcgtc agtttgtgct gcatctttaa atgattgcat
      181 tgcgctattc agcgtaattg gcagcagctg cggatcgtca tcaatcttct ctgacagcgg
      241 ctgatgtact tcaaccagac gcgcaccgtt tggttcggca gagactttaa tcggggtgtt
      301 gatgatattc actttggtgc ctggggtgac ctggctaaag agtgttttga tatcgtcatc
      361 ccgcagacga atacagccag aacttacccg catgccaatg ccgaaatcag cgttcgtacc
      421 gtgaagcaaa taaacgccgc cataggccgc cagacgaatc gcatgatggc ccattgggtt
      481 atccggtcca gccggaacta ccgcaggcaa ctcaattccc tgtgccttat accgcgcgcg
      541 aatgtttgcc gttggcgtcc aggttgggtt tgcacgcttg tcagaaacgg tggtcaccat
      601 tgtcggtgtc agcgtgtcac cacctaattg accaatgccg atgggatata cggttaccga
      661 attttttccc ggcggataat aatagagacg cagctccgca atgttgatca caatgccttc
      721 gcgcggcgcg tctggaagta gggtttgcaa cgggatcgtt aacacgctac ccgcgcgcgg
      781 tacgtaagga tcaacgccgg ggttagcctg taacagagcg agaaagccga cgttatattt
      841 tttggcgatg gcttccagag aaccaccgtc attttccaca acatgaaatt tgttttcacc
      901 aaccagacga ctgcctgctg acggcagcgg ccaggtgttg gcttttgccg gtagcgccag
      961 cgccacggca gcggcgaacg taaaaaatgt tagccagcga gaaaaacgcg ttttgatcat
     1021 caccaaagtc cataataaat ataaggttat tgtaataaaa aggtaagtct gaattatgga
     1081 gggtgacagt gtcggataat gcagggaagt gcaaagaatt tgtaaatatt gcagatgggg
     1141 gcgcagaaac gcccccgatt taccattaag cgatcgcgtt ctcttccagt tcacgcataa
     1201 actggcgtac ccattcgata cgcgttttcc gctcgctcaa atcctgaata aacttcagac
     1261 gcgtcggacc atcaaggcgg taatgctgcg gctgtttttg cagcaaacca atcaaccagg
     1321 ccggattaac gtgattcttc tcggcaaatt cgatcacgcc gcctttctca ttaccttcca
     1381 gcttcctgat ccccagtttc tgcgcttgct ggcgcagacg ggcaatatcc agcagggtac
     1441 gcgccggatc cggcagcagg ccgaagcgat cgataagctc gactttgatc tcttccagtt
     1501 cgttttccgt tttggcgctg gcaatacgtt tgtagaacga cagacgcgtg ttcacgtcag
     1561 ggatgaaatc atctggcaat agcgacggca tccgcagctc gacttctgtt tgctggctgg
     1621 tgagatcttc cagcgacggc tcgcgtccgg ctttcagcgc atcgacggcg ttttccagca
     1681 actccatata cagcgagaaa ccgatggttt ccattgagcc gctttgttct tcgccaagca
     1741 gttcacccgc gccgcggatc tccagatcgt gcgttgccag cgcaaaacct gcaccgagat
     1801 cttccagcga ggcaatcgct tcaagacgtt tttgcgcatc ggtagtcatc gcttttggat
     1861 gcggcgtcag cagccatgca tatgcctggt ggtgcgaacg cccgacgcga ccgcgcaact
     1921 ggtgcaactg tgccagaccg aagtgatccg cgcgttcaat gataatggtg ttggcggtag
     1981 gaatgtcgat cccggtttcg ataatggtgg tacaaaccag cacgttgaaa cgttgatgat
     2041 ggaaatcatt catcacccgt tccagttcgc gctcacgcat ttgcccgtga ccgatagcaa
     2101 tccgcgcttc aggtaccagt tctgccagcc gttcggcggc tttctggatg ttttccacat
     2161 cattgtagag ataataaacc tgtcctccgc gcaaaatttc acgcaggatc gcctcccgga
     2221 ccaccagact gtcatactca cggacaaagg ttttaactgc cagacgacgg gcgggcggcg
     2281 tggcgataat cgacagatcg cgcattccgc tcattgccat attcagcgta cgtgggatcg
     2341 gcgttgcggt aagcgtcaga atatccacgt tcgcgcgcat cgctttaatg cgctctttat
     2401 gacgcacccc gaagcggtgt tcttcatcga caatcagcag gcctaaatct ttaaacttga
     2461 cgtcactttg cagcagtttg tgcgtaccga tcagaatatc aattttccct tccgccactt
     2521 ccgcaaggat ttgcgtctgc tctttggcgc tgcggaaacg ggagatcatt tcgatacgta
     2581 ccggccagtt ggcgaaacgg tcgcggaagt tgtcgtaatg ctgctgcgcg agaagggtgg
     2641 taggcaccag caccgccacc tgtttgtggt tatctaccgc catgaaagcg gcgcgcatcg
     2701 ccacttctgt tttaccaaag ccaacatcgc cgcacaccag acgatccatt gccagcggct
     2761 gacacatgtc actaagcacc gcattaatgg cctgcgcctg atccggcgtg gtttcaaacg
     2821 ggaagctgtc gcagaacaac tgatactgct cgcgatcgtg tttaaacgcg aagccctctt
     2881 tggcggcgcg ttgcgcgtag atatccagca attccgccgc cacatcacgc actttttccg
     2941 ccgctttctg ccgcgcgcgt gaccaggcat cgccaccaag tttatgcagt ggtgcgtttt
     3001 cttctgcgcc acccgcgtaa cggctaatca gatgcagtga cgacaccgga acatacagtt
     3061 tggcgtcgtt ggcataggtg agcatcaaat actcgccagt aatgcctcca gcttcgagcg
     3121 tggtcattcc ggcataacga ccgacgccgt gctccagatg gaccaccggc tgaccaatat
     3181 gcagctccgc aaggttacgg atcagtgtat cggggttgat ggcgcggcga gaatcctgac
     3241 gacgacgggc aacgcgttca ccgagcagat cgctttcgca aatcagcgcc agattacgta
     3301 ccgtatcgac aaaaccatgc tctgcagcgc caatcatcag ataacgccca cggtcgctgg
     3361 cttcatcaag acgcataatg cgttgcggag caattttaat tcgcgcgagc agttcaccca
     3421 acgcttcacg gcggccttca ctttctaccg agaacaccac cggaccgtcg aaagactcga
     3481 ggaacttacg cagcgcatcc agcggcgctt tttgttgtgc ctgaatggcc aggtctggca
     3541 gtttctggaa acctaaattg gcattcgctg cttttgtcgg taaatgttca gtttttagct
     3601 gcacacgggg ccagtttttc agctctgaga agagctcatc cacccgcagc cagagcgatt
     3661 gtggtggcaa cagtgggcgc attgggtcga tgccgcgatt ctcaaaacgc gcgagcgtgt
     3721 cagcctggaa acgttcggca ctgttttcca gatcgccagt attcaccaac agcgtattgg
     3781 cagggaaata actgaacagt ggcggcagcg gttcgctgaa gaatagcggc tgccagtact
     3841 cgatcccggc aggtaatgtg cctttactca cttgctgata aatatgttcc gggtcgcgct
     3901 tcacttcgaa ggtatcacgc cactggctgc ggaacagttc aattgccgct ttatcggtcg
     3961 gaaattcgtg cgcgggcaac agattgatcg cttctacttc ctccagcgtg cgctggctat
     4021 cgacgtcaaa cacccgcagg ctgtcgattt catcatcaaa gaaatcaaga cgataaggca
     4081 gctcactccc catcgggaag agatccaaca acgcgccgcg cgtggcgtat tcgccgtgct
     4141 ccatcacctg gtcaacatgg cgataaccgg cgctgtccag ttgggttcgt aatgcatctc
     4201 gtgacaggcg ctgacctttt ttcatcacca gcgcatgacc gtggagaaag ctgtgcgggc
     4261 aaacgcgctg cataagcgta ttcaccggaa caatcagtac gccacgctgc atcgatggta
     4321 actggtaaag ggtggaaaga cgcgaggaga taatgtcctg atgaggcgaa aaactgtcgt
     4381 aagggagggt ttcccagtcc gccagattca tcaccatctg atcggtgaac tggctgattt
     4441 catcatgcaa acgcagagca ttttgcatat ctggtgcaat gagtaccacc ggaccggcgt
     4501 gacgttcggc aatttctgct accagcgtcg cgcaggcagc gccggttaac tcgcccagca
     4561 gacgctgctc acccgctttg acgggcagcg tataacgata ttgttcaggc ataacggttg
     4621 tcagattctc gttaggatat gcctcaacat atggggcata tctctgataa gcaatgctgt
     4681 tcattatccg taatcgacat ggtttagcaa attgaatcgc cccggctggg gcgatggctt
     4741 agcgggagta actgacggta gcgggcagag aaggcgggga gaacaacaga tcgctgaatg
     4801 cgcgctgtga aagttttctt accagcaagc ccgcaacagt acaaatcaac aaactgacaa
     4861 aggggtaaat cagcaggagc gtcagttcga cttgcggcga ccagcgtacc gcgttcattt
     4921 gcggaatcag gcttaagctg aatatttcta ccagaatgcg atgggtggta tagatagcaa
     4981 tggtgttgga gccaatcaca ttcagcaggc tggaggaacg cataccgaaa cgctgctcgt
     5041 actgataaaa cagcttcatg attaccacaa tcgataccag cgacaacagc agcgagatat
     5101 taaacaacca ggcaccgacc gccagaacgg tcagcaaaga agccatcagc agatggcggc
     5161 gcaacggtac cgctttaaca caggtcatta atgttgcgcc aaaccatgcg ccaaggctgt
     5221 aataaggcaa attgcggatc acactgttca ttccccacca cggtgtgggt acgaaattaa
     5281 cagccacact catcagtaca aacagaacaa ataacggcag ggccaggggg ttaaaaattt
     5341 tacatatcac gaaatagaca attaacgcat acagatacca caagctggtg ctggcggtga
     5401 tcatcccgtg caggaactca ccggtggaat cggcataagc ggcattggag gcattgctta
     5461 aatcgcgctc aggtgccagc cactggttca gcgcacttaa cgccagccac tgcaccacgc
     5521 cccaaagcgc cagcacccag aagatgttcc agatgcgttt atcgagacaa tttccccacg
     5581 gtacgctgtc gatatagcgg cgaatcaaat agccagagat aaagaaaaaa accggcatac
     5641 gaaagggtgc aaggtaaaga ttgaaataga tccagcattt gctcaggact tccgataacg
     5701 gatgctgaaa agtggtcaga tgcggataaa aggtaatgac cgagtgataa atcaccacca
     5761 gacaaataca taaccctttg atctggttaa tccatagctc tttttgtttc atcgggacaa
     5821 cacgctcttt ttatttaaca tgcggttgat cctgcggggc gagtcgcgtg gtgtaatgcg
     5881 tatctgtctg tatttggtta tttttcagat aaagatcagg ccacatggcc gatgataaaa
     5941 tgaggcactt tagccgattg atttgctggt acttttcaga ttagccctga cgatcactta
     6001 cagttcagac gtttacccat cctgctttcg cttatatact cgtgtctttg ctacagcaac
     6061 cagacggatt tcatgtacca acctgtcgct ctatttattg gcctgcgtta catgcgtggg
     6121 cgtgcagcgg atcgcttcgg tcgtttcgtc tcctggcttt ctaccatcgg cattaccctc
     6181 ggggtgatgg cgctggtcac agtattgtca gtgatgaacg gctttgagcg cgagctgcaa
     6241 aacaacatcc ttggcctgat gccacaggca attctctctt ctgagcatgg ctctcttaac
     6301 ccgcagcaac tcccggaaac ggcagtcaaa ctggacggcg ttaatcgcgt cgcacctatt
     6361 actaccggtg atgtggtact gcaaagcgcg cgcagcgtgg cggtcggggt gatgctgggt
     6421 atcgacccgg cgcaaaaaga tccactaacg ccgtatctgg tcaatgtgaa acaaactgac
     6481 ctcgagccgg ggaaatataa tgtcatcctc ggtgaacagc ttgcctcaca gttgggcgtc
     6541 aatcgcggtg atcaaatccg cgtgatggtg ccatctgcta gccagttcac gccgatgggg
     6601 cgtattccaa gtcagcgcct gttcaatgtg attggcactt tcgccgccaa cagtgaagtc
     6661 gatggctatg aaatgctggt gaatattgag gatgcctcgc gtctgatgcg ttatccggca
     6721 ggcaatatta ccggctggcg tttgtggctg gatgagccgc tgaaagtcga ctcattaagt
     6781 cagcaaaaac tgcctgaagg cagcaaatgg caggactggc gtgaccgtaa aggcgagctg
     6841 ttccaggccg tacgcatgga aaaaaatatg atgggcttgc tgctgagcct gattgtcgcc
     6901 gttgcggcgt ttaacattat tacctcgctg ggactgatgg tgatggagaa gcagggcgaa
     6961 gtggccattc ttcagactca ggggctgact ccgcggcaaa tcatgatggt ctttatggtg
     7021 caaggggcca gcgccgggat tatcggtgcg atcctcggag cggcgcttgg cgcactgctt
     7081 gccagccagt tgaataatct gatgccgata atcggcgtcc tgcttgatgg cgcggcgctg
     7141 ccggtcgcta tcgagccttt acaggtcatt gttattgcgc tggtggcgat ggctatcgcg
     7201 ctgctgtcta cgctttaccc ttcctggcgc gctgccgcca ctcaacccgc tgaggcttta
     7261 cgttatgaat aagatcctgt tgcaatgcga caacctgtgc aaacgctatc aggaaggcag
     7321 tgtgcaaacc gatgtactgc acaatgtcag tttcagcgtg ggcgaaggtg aaatgatggc
     7381 gatcgtcggc agctctggtt ccggtaaaag caccttgctg cacctgttag gcgggctgga
     7441 tacgccaacc tccggcgatg tgatctttaa cggtcaaccg atgagcaaac tgtcttcggc
     7501 ggcgaaagca gaactgcgca accagaagct gggatttatt tatcagtttc accacctgct
     7561 gccggatttt accgccctgg aaaacgtggc tatgccgctg ttgattggca agaaaaagcc
     7621 cgctgaaatc aacagccgtg cgctggagat gttaaaagcg gtggggctgg agcatcgtgc
     7681 gaatcaccgc ccatctgaac tttctggcgg cgaacgccag cgtgtggcga ttgcccgtgc
     7741 gctggtcaat aacccgcggc tggtactggc ggatgaacct actggtaacc tcgatgcacg
     7801 taacgccgac agcatcttcc agttgcttgg ggaattgaat cgcttgcagg gcaccgcctt
     7861 cctggtggtt actcacgacc tgcaactggc gaaacgtatg agccgccaac tagaaatgcg
     7921 tgatggacgt ctgacggcgg aactgagcct gatgggggcg gagtaatggc gatgccttta
     7981 tcgttattga ttggcctgcg ttttagccgc ggacggcgac gcggcggcat ggtgtcgttg
     8041 atctccgtca tttctaccat tggcattgcc ctcggcgtgg cggtattgat cgtcggctta
     8101 agcgcgatga acggctttga acgcgaactg aataaccgca ttctggcggt agtaccgcac
     8161 ggtgaaattg aggcggtaga tcagccgtgg accaactggc aggaagcact ggataacgtg
     8221 cagaaagtgc cgggcattgc cgccgctgcg ccgtatatca atttcaccgg gctggtggaa
     8281 agtggcgcga atctgcgcgc aatccaggtc aagggcgtta acccgcaaca ggaacagcgt
     8341 ttgagcgcat taccctcgtt tgtccaggac gatgcgtgga gcaattttaa agcaggcgaa
     8401 cagcaaatta tcatcggcaa aggcgtggcg gatgcgctga aagtgaagca gggggattgg
     8461 gtgtcgatta tgatcccaaa ttcgaatccc gagcataaac tgatgcagcc aaaacgtgtg
     8521 cgtttgcacg ttgccggtat tttgcagttg agtggtcaac tcgatcacag ttttgccatg
     8581 atcccgctgg ccgatgctca gcaatatctt gatatgggtt ccagcgtgtc aggtattgcc
     8641 cttaaaatga cggatgtttt caacgccaat aagctggtac gcgatgcggg tgaagtgacc
     8701 aacagctatg tttatattaa aagctggatt ggtacttacg gctatatgta tcgcgatatt
     8761 cagatgatcc gcgccattat gtatctggcg atggtactgg tgattggtgt ggcctgtttc
     8821 aacatcgtct ccaccttagt gatggcggtg aaagacaaga gtggcgatat cgcagtatta
     8881 agaacgttgg gtgcgaaaga tggtttaatc cgcgccatct ttgtctggta tggattgctg
     8941 gcagggctgt tcggcagcct gtgtggtgtg attatcggcg tagttgtttc actgcaactt
     9001 accccgatta ttgagtggat tgaaaagctg atcggccatc agttcctctc cagcgatatc
     9061 tattttattg acttcctgcc atcggaattg cactggctgg acgtcttcta cgtactggtc
     9121 acagcattgt tgctgagtct tttggcaagt tggtatccgg cgcggcgcgc cagtaatatt
     9181 gaccctgcgc gagtccttag cggccagtaa aggcagtaca ttaaaacaag gagcggcaat
     9241 gtattacggg tttgatattg gtggaacaaa aattgcgcta ggcgtgtttg atagcggtcg
     9301 gcagttgcag tgggaaaagc gggtgccgac accgcgtgac agctatgacg catttttaga
     9361 tgcagtgtgc gagctggtag ccgaagctga ccaacgtttt ggctgtaaag gttctgtcgg
     9421 cattggtatt ccgggtatgc cggaaacaga agatggtacg ctgtatgccg ccaatgtccc
     9481 tgctgccagc ggtaaaccgc tgcgtgccga cctgagcgca cgtcttgatc gcgatgtacg
     9541 ccttgataac gatgccaact gttttgccct ttctgaagca tgggatgatg aatttactca
     9601 atatccactg gtgatggggt tgattctcgg caccggcgtt ggcggcgggc tgattttcaa
     9661 cggtaaacca attaccggta aaagctatat taccggcgag tttggccata tgcgtctgcc
     9721 ggttgatgcg ttaaccatga tggggctgga tttcccgtta cgccgctgcg gctgtggtca
     9781 gcatggctgc attgaaaatt atctgtctgg tcgcggtttt gcgtggctgt atcaacacta
     9841 ttatcatcaa ccgttgcagg ctcctgagat cattgcgctt tatgatcaag gcgatgagca
     9901 ggcaagggcg cacgttgagc gttatctgga tttattagcg gtttgtctgg gaaatatcct
     9961 gaccattgtt gaccctgacc tggtcgtcat tggtggtggc ttatcgaatt tcccggcaat
    10021 cacaacgcaa ctggcggaaa ggttgcctcg tcatctctta cctgtagctc gtgttccgcg
    10081 cattgaacgc gcgcgccacg gtgatgcggg aggaatgcgt ggtgcggcct tcctacatct
    10141 aaccgattaa tcaacagagg ttgctatgct gtcgcgtcgg ggtcatcggt taagtcgttt
    10201 tcgtaaaaat aaacgccgcc tgcgcgagcg tttgcgtcag cgtatttttt tcagagataa
    10261 agtggtgccg gaagcaatgg aaaaaccaag agtactcgta ctgacagggg cagggatttc
    10321 tgcggaatca ggtattcgta cctttcgcgc cgcagatggc ctgtgggaag aacatcgggt
    10381 tgaagatgtg gcaacgccgg aaggttttga tcgcgatcct gaactggtgc aaacgtttta
    10441 taacgcccgt cgtcgacagt tgcagcagcc agaaattcag cctaacgctg cacatcttgc
    10501 gctggcgaaa ctgcaagatg ctctcggcga tcgctttttg ctggtgacgc aaaatatcga
    10561 taacctgcat gaacgcgcag gcaataccaa tgtgattcat atgcatgggg aattgctgaa
    10621 agtacgttgt tcgcaaagtg gccaggtcct cgactggacc ggagacgtta cgccagaaga
    10681 taaatgccat tgttgccagt tcccggcacc cttgcgcccg cacgtagtgt ggtttggcga
    10741 aatgccactc ggcatggatg aaatttatat ggcgttgtcg atggccgata ttttcattgc
    10801 cattggtact tcggggcatg tttatccggc ggctgggttt gttcacgaag cgaaactgca
    10861 tggcgcgcac accgtggaac tgaatcttga accgagtcag gttggtaatg aatttgccga
    10921 gaaatattac ggtccggcaa gccaggtggt gccagagttt gttgaaaagt tgctgaaggg
    10981 attataaagc gggaaaaatt gcctgatgcg ctacgcttgt caggcctgtg aaggggcgca
    11041 attaattgaa tttgcgggtt ttgtgggccg gataaggcgt tcgcgccgca tccggcataa
    11101 tacacgcgaa ctttactgcc tcttttaccg tttactcgtc catagtaacg cggcaataaa
    11161 cgtacagaca ccaatcagcc ctgcccagag tggcgatatt ctggtaatcg caaagctgtt
    11221 atcgatatac aaacataaag cctgataacc catattggca acagccatcg ccactgcaaa
    11281 ttttaacgca taataaaggc gcgttgtgta gttaaaaaat gcagcaaaga cgatgaatgc
    11341 aactgcccag gcaaaaaggc ctaatgtcgt ggtactgccg ggtggatcat tttcatgctg
    11401 ttgtccggga tgcggataat atgtcagtgg tggcgtcggt tgttttaata tctgtgcttg
    11461 taaaacagcc aatgcattat tgataccctg ataccagagg tccgcatgta aataagccag
    11521 cgtgtgattt tctaccagaa ggccgagatg tttatcgtcc agaccgcttt caacctggcc
    11581 gttggttatc ataattaacc gtggctcgcg ggtagtaaag agtaacagaa cacttccttt
    11641 tacattactc attgaagatg ccgcatgcgc cagcatcgct ttgccatttt gcctgagact
    11701 ggcttcatta ttaatgtcgg gtaaaaccac aataaacggt gcaactccgg tttgttggcg
    11761 aaaaagctcg gctttatgcg cgatctcttc agcatctggt acagtaccgg taacatccgt
    11821 aaaaagtgtc ttcattattg gaattaaggg cttactggtt gccgtcagag gcaggagtat
    11881 cagtaaactg agcaatatta tgattttttt catgggcggg acttccgttt cctgcgtgtc
    11941 tttttagagg agggcatact gattaataaa ccgacggaga taaaaataac gcccataatg
    12001 ccgataaacc cccatttaaa aaaattaacc cacgggttat ttatctcagc cttttcagga
    12061 tgtcctggag aataataaac attaacttta tcgccttcgc tgccttcata aaaatcgctg
    12121 ccaatactcg aattgaaaat tagcgtgtaa tctggcgtcg gacgaaaggc aacgacggga
    12181 taccacgaac catttttacc cgtgcgatga gaatgactgg agtgccagac ggtatcaaca
    12241 atgacgcctt cagtatgaat cgcgtctttg ctataggtga actggttata aaagataaca
    12301 acagaaatga ggatcagtac cagaccgata ccgaagaata tacgaaagaa aactctactg
    12361 tcctggctca ttagccacat ccttgctaaa taaaaaacgg gcggtaatat caccgcccgc
    12421 ttgctgaatt aacgtcctgc tttcagcttc tgataatact cttcataaat gctgctggct
    12481 gcgccaacgt cattctgcca ttcaccattt ttaatggttt cagcatccgg gtagagcgtt
    12541 ttatcgttcg ccacttccgg acttaacagc ttacgcgccg caaggtttgg cgttggataa
    12601 ccgatagttt cagcaacctg ttttgccaca tccgggcgca gcaggaagtt gatcaatttc
    12661 agcgcgcctt ctttgttttt ggcatttgcc gggatcgcca ggctgtccat ccagaaaata
    12721 ccgccttctt tcggccacac cacatcaatt ggcgtacccg cctggcgtgc aacgaaagca
    12781 gaaccgttcc agatcatgcc gaggttaact tcgccttcca tatacgggtt cgccgggtta
    12841 tcggagttaa acgccgcgac gtttggcatc agctttttca gctcgttgta tgcagcttca
    12901 atctctttcg gatcggtggt gttaccggag tagcccagct tacgcagcgc catctggaac
    12961 acttcacggg catcgtcggt cagcagcagg ctgcctttgt actcaggctt ccacagatcg
    13021 gcccagctgg tgacagattt cggatccacc gcatcaccgt taacgccaat cgccgtcgca
    13081 ccccagatat acggaatgga atagtcgtta ttcgggtcaa acggcttgtt gagcatgtct
    13141 ggatcgaggt tgctgaaatt gcttaacttc gacttgtcga tcttctggat catcccttct
    13201 ttacgcattt tatcgacgta ataggttgaa ggaaccacca ggtcataggc accgtctttg
    13261 tacgttttca gcttcgcgta catggtttcg ttcgactcgt aagtcgaata gataacctta
    13321 ataccggttt ctttggtgaa ctgttcaagc agtcctggcg gcacgtactc ggtccagttg
    13381 tagaaataca gcgtgttgtt gtcatcggcg tgagcggcgc tcatgcccag tgccagagca
    13441 cccgccgcga gcaggtggcg tgaccatttt ttcatttaac gtcccctgtg ttacctttcg
    13501 ttttatcacg agcaataagc tggctggcaa ttaccatcac cagcgacagc accagtaata
    13561 tggttgccag cgcgttaact tccggcgata cgccgacttt gaccatcgaa taaattttta
    13621 acggcagaat ttcataactc ggcccggtga caaacgaaga aaccaccacg tcgtccatcg
    13681 acagggtaaa gcttaacacc cagcccgccg ctaccgctgg cattgccagt ggcagaatga
    13741 tttttcgcag aatggtaaat tcgctggcac cgagatcttt cgccgcttcc agcattcgca
    13801 cgtcaaaacc tttcaggcgc gaatacactg tcactaccac aaatggcagg cagaaggtga
    13861 tatgcgagaa cagcagcgac cagaagccaa gctgaatacc cagcagcata aacagcacca
    13921 gcagcgaaat cgccattacg atatctggtg acatcatcac cacaaacagc attccgctaa
    13981 cgaacggctt accacgaaag cgataacggt acagcgcaac tgccgtcagt gaaccgataa
    14041 gcgtagcaaa cgtcgccgaa aacaccgcca ttgtaagtga atgctgcgct gcctgtaaca
    14101 ggctgtcgtt gttcatcagc aggctatacc atttggtggt aaaaccctgc cagttgatgc
    14161 caaagcgcga gctgttaaag gagttcacaa tcaaaataat gattgggata tacaggtacg
    14221 cgtagatagc ggtcataaaa ccgccgcgaa gcagtcgacc gatcattcga gttccacctt
    14281 cttattcagc aaacgagaag cgcgccagta aaccagcaac atcaggccca ttacgatagt
    14341 cagcgtaatg ctggtggctg caccaaacgg ccagtcacga atattgagga actgtacctt
    14401 gatgacgtta ccgatcagca ggtttttcgc accgcccatc aggtcggaca catagaacag
    14461 gcccatcgct ggcagcatca ccagcagaca tccggcaata attcccggca tcgtcagtgg
    14521 gataatgatg cgaataaagg tctgcaactt gctggcaccg agatcgcgcg ccgcctcaag
    14581 caacggctta tccagttttt cgatactgga gtacagcggc atcaccataa acggcagcag
    14641 aatgtaaacc agaccgataa tcaccgcact aggcgtgaac atgatgcgaa ttggtgtatc
    14701 gataacgccc agccagagca aaaactcgtt gagatagcct ttggtgctga ggaaaatttt
    14761 cagcccgtaa atacgaatca atgagttggt ccagaacgga acaatcagca gaaacagcag
    14821 cagcggacgc accttgtgtg gcagcttcgc cagaaaccag gcaaaaggat agcccagcac
    14881 caggcaggcg agggtggcga tcagcgccat attcagcgag tgcaatagca cttcaaaata
    14941 gagcggatcg agcagacgcg tgtagttatc cagcgtaaag accattttga cgaaactggc
    15001 gtcgtcgcgg gtcaaaaagc tggtgccaat gatcatcagg ttgggcagaa agataaacaa
    15061 cacaagccaa ccgacaatag tgacaatcac tacattctgg aacttacttg tgttcttcat
    15121 cagccagtac gacctcccag ctttctaccc aattaatggc cattttttgg tcgagagagt
    15181 ggtcaaagtc aggatcgtct tcattgaaga attcgctgac catcaccatc ttgccatttt
    15241 ccagctcaac aaccgactcc agcgtcatgc ctttgtagtt acgctcgcga acgtaaccaa
    15301 tcagcccttc ggcgtggttg tcgtcgttaa tctcttcaac acgtaagtct tccgggcgca
    15361 gcagaacatg cagtttttgc cccggttcaa cggcgaagtt aacgtagata ttacattcgc
    15421 ggccttcaac gttggcgcgt acgcgctgct cgtcgagacg ttcgatgaca gtggcgttaa
    15481 acatattgat ttcgccaata aacccggcaa caaacaggtt tttcggctct tcgtagattt
    15541 cacgcggcgt gccgtcttgc tcaatgcgac catcgcgcat caccacgatc ctgtccgaca
    15601 tggtaagtgc ttcttcctgg tcgtgagtta cgaacacgaa tgtaatgcca agcttacgct
    15661 gtaacgcttt cagctcgttc tgcatttgct tacgcagttt gtaatccagc gctgagagcg
    15721 actcatccag caacaacaga cgaggcttgt taaccaccgc gcgagcaatg gcgacgcgtt
    15781 gctgttgacc accagagagc tgatgcggtt tgcgttgagc gaaggtttcc agctgcacca
    15841 tccgcagggc ttccatcacg cggggcgtaa tttcagctgc gggggttttt tgcatgcgca
    15901 acccaaaggc cacattttcg aacacggtca tgtgggggaa aagtgcgtag ctttggaaaa
    15961 cagtgttcac atagcggttt tccgccggaa cgtgggtgat gtcctcgtta tccagcatga
    16021 tgcgtccgga atcaacagtt tccagacctg caatcaggcg aagaacggtt gttttaccgc
    16081 agccagaagg gccaagcagc gtgaggaact cgccattgtt gatagtcaga tccagctggg
    16141 gaatgacctc tttaccatca aagcatttgc gaattcccgc caattgcacc agcggtgaaa
    16201 gcgaactcgg ttgtttattc aattttttac tctgtcccat gtaaacgcaa cggatggctt
    16261 accgatgcgg ggtttgtggt taaccacctt ggtgactctt aatgagggcg gtaattctac
    16321 ggcaaaccgc ttgaatcgcc aatctttgtt gtgaattact ggcttagctt tatattcatt
    16381 aaggtaatgc tgataaatat tcccgcttgc agggctaaaa gtgacctgac gcaatatttg
    16441 tcttttcttg cttcttaata atgttgtcac aaaaagtgag ggtgactaca tggataaact
    16501 acttgagcga tttttgaact acgtgtctct tgatacccaa tcaaaggcag gggtgagaca
    16561 ggttcccagc acggaaggcc aatggaagtt attgcatctg ctgaaagagc agctcgaaga
    16621 gatggggctt atcaatgtga ccttaagtga gaagggcact ttgatggcga cgttaccggc
    16681 taacgtccct ggcgatatcc cggcgattgg ctttatttct catgtggata cctcaccgga
    16741 ttgcagcggc aaaaatgtga atccgcaaat tgttgaaaac tatcgcggtg gcgatattgc
    16801 gctgggtatc ggcgatgaag ttttatcacc ggttatgttc ccggtgctgc atcagctact
    16861 gggtcagacg ctgattacca ccgatggtaa aaccttgtta ggtgccgatg acaaagcagg
    16921 tattgcagaa atcatgaccg cgctggcggt attgcaacaa aaaaacattc cgcatggtga
    16981 tattcgcgtc gcctttaccc cggatgaaga agtgggcaaa ggggcgaaac attttgatgt
    17041 tgacgccttc gatgcccgct gggcttacac cgttgatggt ggtggcgtag gtgaactgga
    17101 gtttgaaaac ttcaacgccg cgtcggtcaa tatcaaaatt gtcggtaaca atgttcaccc
    17161 gggcacggcg aaaggagtga tggtaaatgc gctgtcgctg gcggcacgta ttcatgcgga
    17221 agttccggcg gatgaaagcc cggaaatgac agaaggctat gaaggtttct atcacctggc
    17281 gagcatgaaa ggcaccgttg aacgggccga tatgcactac atcatccgtg atttcgaccg
    17341 taaacagttt gaagcgcgta aacgtaaaat gatggagatc gccaaaaaag tgggcaaagg
    17401 gttacatcct gattgctaca ttgaactggt gattgaagac agttactaca atatgcgcga
    17461 gaaagtggtt gagcatccgc atattctcga tatcgcccag caggcgatgc gtgactgcga
    17521 tattgaaccg gaactgaaac cgatccgcgg cggtaccgac ggcgcgcagt tgtcgtttat
    17581 gggattaccg tgcccgaacc tgttcactgg cggttacaac tatcatggta agcatgagtt
    17641 tgtgactctg gaaggtatgg aaaaagcggt gcaggtgatc gtccgtattg ccgagttgac
    17701 ggcgcaacgg aagtaagcga aaagggatgc ggcatgtgat gccgcatccg gcttaaatcc
    17761 aaacttaccc ttcgaagaac cagtatccgc tattgaccag cgccgcgagc atcgcgagga
    17821 atgacggatc ttccagcgca tcgccaaaat tctccgcggt cagcgcaatg ttgctggcga
    17881 gcgcatccag tgccggacgg tgcggggaat cgatcttctc accattggca tacacgtcgt
    17941 cgccaatgcg caatacgcgc agacccccca ggcgcaccag cacatcacct tgtttcagcg
    18001 catcgtagat ttcatccggc tgataaggcg gctctggcgg cgcgatatcc agttcatgac
    18061 gtgactggga tataaactcg ccaaaccatt gcttaaaatg ttctggctgg ttgatcaatt
    18121 cgagcatcat ctcacgcagt ttatccatct cttgcggcag aacgtccgca ggatgagcgc
    18181 gaggtggaac atcaggatcg ctgtagtagt tgccgcccag ttcacgttgc agcacataat
    18241 cggcaaatcc gctaatcagt tcccgcgtat ttggcgcgcg aaaacccacg gaatagttca
    18301 tcgcattttc cagcgcgtag ccttcatgcg ggaatcctgg cggaatataa agaatatcgc
    18361 caggctccag ctcttcatcg atgatggctt cgaacggatc gacctgtaac agatccgggt
    18421 gagggcagtg ctgtttcatt tgcagctttt cgcccactcg ccagcgacga cgaccggtac
    18481 cctgaatgat aaacacgtcg tactgatcga gatgcgggcc gacgccgccg cccggtacag
    18541 aaaaagagat catcagatca tcaatacgcc agtccggtag ttcacggaac ggtcgcatta
    18601 gcgcggcggt cggctcatgc cagtggttca ctgcttgcac taacaatgac cagttagttt
    18661 caccgagatg atcgtagctt tcgaatggac cgtggctgac ctgccatttg ccatcctgat
    18721 gactgaccag tcgactgtcg acttcgcttt ccatcgccaa acccgccaac tcgtctggag
    18781 agatcgggtc aataaaatta ttaaagccgc gttttaacac caccggacgt ttctgccagt
    18841 gacgttcaag aaaatcgggc cagttaagag tgagttggta ttccatgtta agcatccaca
    18901 ggctggtatc tgcaaccgat tataacggat gcttaacgta atgcgtgaag tatggacata
    18961 tttattcatc tttcggtgca gaatgctggc gaccaaaaat cacctccatc cgcgcaccgc
    19021 ccagcatgct ctctccggcg acgattttac cctcatattg ctcggtgatt tcgcgggcta
    19081 ccgccagccc tacaccttgc ccagggcgta aagtatcaac ccgttgacca cggtcgaaaa
    19141 tgacctctcg cttgcttaat ggaataccgg ggccatcatc ctcgaccaca atatagagat
    19201 gctcgtctgt ttgccttgca gatatttcga caaactcgag gcaatattta caggcattat
    19261 ccagcacgtt gcccatcacc tcgacaaaat cgttctgctc accgacaaag ctgatctctg
    19321 gcgaaatatc gagagagata ttgacccctt tgcgttgata cactttgttc agcgccgagg
    19381 tgagattgtc cagcagtggg gcgaccggat gcagctcgcg gctaagcaat gtcccgccgc
    19441 gcatactggc acgatgcagg tagtagccaa tttgctgtga aatgcggctg atttgctcca
    19501 gcattaccgg ctcagcatca ctgacgctca tcttctcact acgcagagaa cgcagcgtac
    19561 tttgcagcac cgccagtggc gttttcagac tatgggtcag gtcggtgagc gtcgtacgat
    19621 atttgtcgta acgttcgcgt tcacttttta acagtcggtt caggtttcgt accagactag
    19681 tcagttcccg cgttgtggct ggattgagca attcgcggtt atgttcttcc agttcgcgga
    19741 cttcttttgc cagggcttcg atggggcgta aactccacca ggcggcgacc cacagcagcg
    19801 ggatcactaa cagcagattg gctgagagca catagataaa ccagctccag accatatagg
    19861 aactttttag ctccaccgga atggtatcca ccaccacaat ggttaacttt ggcatccgcg
    19921 atgttgccgg gtagacgttt accgccaccg agtgggtcat ctccgcgtcg tcatcatctt
    19981 cccgcacttc ctgcaactgt tgctgtatcg aatgatctcc actcagcaag aggctggtat
    20041 cgttaacatc cgcttcaatt tcatgaaaac cgttcgattt tagccagtcg ggctggatca
    20101 tcttcatcag ccagggcacg tcacgttgcg cccataaaag ctgcccgttc tcatcataaa
    20161 ttagtgtcat cgtggggctt tgcttgtcga tattttcggg taactcgaca tgcaacttat
    20221 tgttttccca cttcgcaagg gtatagaaca gattgctctc gccacgtaac agccgaaacg
    20281 tggttttatc gaaactgacg ctataaccga tcagcgcaac cattccgtag gcaagcgaaa
    20341 gcaccaatac tactgctgcc gttgctaaca gaaaacgtac ccgcagcgag agcgggaaaa
    20401 aaagacgcag taattttttc atcagcgcaa ttcgaacaga tagccctggc cgcgaacggt
    20461 ggtaatcact tcttgcggat attgtgcctg aatttttttg cgcagacgtc ccatcagtac
    20521 atcaatggta tggctttccc gcagctccgc atccgggtag agttgtagca ttaacgaatc
    20581 tttgctgacc actttgccat tattgcgtat caacgtttcc ataatggtgt attcgaacgc
    20641 ggtcagtttg atcacttcgt cattaataga taattcacgg cgggagagat caacctgaaa
    20701 cggtggtagc gaaatgacct gtgaagccag accgctatta cgccgcatta atgcctgcat
    20761 tcgcgccatc acctcttcaa tatgaaacgg tttagtcacg taatcatcag caccggcact
    20821 taatacttcg actttgtcct gccagctctc acgggcggtt aataccagaa tcggcagtga
    20881 aacatcattg ctacgccagc ggcgaatcag tgacagacca tcctcgtcag gcaatccgag
    20941 atcgacaatc gcaatatccg gtaaatgttc attgagataa taatcggctt ctttggcatc
    21001 ttctgcgtca tcgacctgat gaccagcatc ctgtatctga actttaagat ggtgacgtaa
    21061 caacgcattg tcttcaacaa ccagtacgcg catttttatt tctccctgtc ttaattatta
    21121 aaatagtgta acgcgattat gtggttatgg gggtaaacat taaataaacc agcgggaagg
    21181 ggaggtaaag tgaaaaaata aaaagcggat aatcttaata agcaggccgg acagcatcgc
    21241 catccggcac tgatttgagg cttatttcag ctcatcaacc atggtgatgg cgcgaccaat
    21301 atagttagcc ggcgtcatcg ctttcaggcg ggctttctct tcttctggca gcgcgagacc
    21361 gtcgataaat tgcttcatgc cttcggcgtc aacgcgctta ccgcgagtca gctctttcag
    21421 cttctcgtac ggtttttcga tgccatagcg acgcataact gtctggattg gctcagccag
    21481 cacttcccag ttgtgatcca gctcctccag cagatggtca tggttcactt ccagtttgct
    21541 cacgcctttc agggtggatt gatacgcaat cagcgcataa ccgataccca cgccgaggtt
    21601 acgcagcacg gtggagtcgg tcaggtcacg ctgccagcgg gaaactggca gtttgcttgc
    21661 caggtgctgc aataccgcgt tggaaaggcc caggttccct tcggagtttt cgaagtcgat
    21721 cgggttaact ttatgcggca tggtggaaga accaatctca ccagcaatgg ttttctgttt
    21781 gaagtggtta agggcgatat aaccccagac gtcacggtca aagtcgatca gaatggtgtt
    21841 gaagcgcgca acgcaatcaa acagttcggc aatgtagtcg tgcggttcga tctgggtggt
    21901 gtacgggttc cactgaatac ccagcgaggt gacgaactct tcgctgaact gatgccagtc
    21961 aacttccggg taagcggcga tgtgggcgtt gtagttaccg acagcgccgt tgattttgcc
    22021 gaggatctcc acctggttaa gctggcggta ctggcgctcc atacggtagg cgacgttagc
    22081 catctcttta ccaatggttg acggcgtggc tggctgaccg tgggtacggg acagcagcgg
    22141 gatatcgcga tactgaacgg cgagatcttt aatgccatca atcagttgac gccagtacgg
    22201 caggatcact tcatcacgcg cggttttcag cattaatgcg tgggagaggt tattgatatc
    22261 ttccgaagta caggcaaaat ggatgaattc agaaaccgcg tgcagttccg ggatatccgc
    22321 cactttttct ttcaggaaat actcaaccgc tttaacgtcg tggttagtgg tacgctcgat
    22381 ggttttgatg cgtgctgcat cttcttcgct gaaactggcg acaattgcat caaggtaacc
    22441 gattgcgtcg gcagcaaaag caggaacttc cttgatcgct gcgtgcgcgg ccagtttttg
    22501 cagccaacgt acttcaactt gtacacggaa tttcagcaaa ccgtattcgc tgaaaatccc
    22561 gcgcagcgcg ctgactttat cgccgtagcg tccatcgaca ggggaaacgg cggtcagtga
    22621 ggataattcc atagatcaca actccggggt taaatgagca agaatttgtt ttgcctgagt
    22681 ggtcaggcga ttacgagaaa acatcagttg cagacgaccg ccgccgacct ggtgccagag
    22741 cacggcggcg cgaatgcctg ccagcagggt tgcgcgaact ttcgcctgca cctgtgggct
    22801 ttgcagtaca gcaggggaac ccgtgacctg aatgcgcggg ccaagcgggc tgataacatc
    22861 aacatagatg gcagccatcg cgctcatcag cgtttcggac tgtaaatcga agtgttcgag
    22921 ctggcgttgc aggccgttga tccggttgcc cagagtgtcg agcgcacctt tcgctgagga
    22981 gagtttgcgc tcaagcacca tcagactgag tgtgtagcgg gttaattcgg cgtttaagcc
    23041 ttggcgactg ctggcattga gtacgccgag caaggtttcc agcccgacgc gcaggttggc
    23101 ttcgctgccg ccaaaaaccg ccagcgttga gctggggttc atatcgataa tactgttgag
    23161 tgagacgtgt agcgcatcgc catcacaatg cccctggtga gcgagttgtt gcaccaggcg
    23221 tgccgactga caaataccgg ccagggcgag ggtgatgtca tagtaattct ttgccacgtt
    23281 cactgcttcc ttgttttaag taaagataat aatcagaccg gcagcggcag acgctgctca
    23341 ataataccgc caccgaggca cacttcaccg ttatagaaaa cggcagactg gcccggcgtc
    23401 acggcggcaa ccggctcatc gaaaatcact tcaatgcgat catcgtccag cgccttgacg
    23461 gtgcacggga tgtcggtctg gcgatagcgg gtttttactg tgcaacgcat agtaccggtg
    23521 aacggttcgc gatcgaccca gtgcagctgc tgggcaatca gaccgacaga catcagacgc
    23581 gggtgttcat ggccttgcgc aacaatcaga atgttgtttt cgacgtcttt atcgaccaca
    23641 taccacggtt cttcggtgcc gtctttggtg ccaccgatac ccagaccttt acgctgaccg
    23701 agggtgtgat acatcagccc ctggtgctca ccaatttcat cgccatcgac ggtaatgatt
    23761 ttgcccggtt gcgccgggag ataacggccc aggaactcgc ggaatttacg ttcgccaatg
    23821 aagcaaatgc cggtagagtc ttttttcttc gcggtgacca gaccaagatc ttcagcaatc
    23881 ttacgcacct gcggtttttc cagttcgccg accgggaaca ggctttgcgc aatctgctca
    23941 tggctgagcg tataaaggaa gtagctctgg tctttattgc tgtccagacc acgcagcagg
    24001 cggctcttgc catcgacatc tgcccgacgt acgtaatgac cggtagcgat ataatcggca
    24061 cctaaatctt cggcggcaaa ttcgaggaaa gctttaaatt tgatctcttt gttgcacaga
    24121 atatccggat tcggcgtgcg accggcttta tattcggcaa ggaacagttc gaagacgttg
    24181 tcccagtact cggcagcaaa gttaacggtg tgcagttcaa tgccgagctt gtcgcagaca
    24241 gcctgggcat cagccagatc cgctgccgct gtgcaatatt cctcaccgtc gtcttcttcc
    24301 cagttcttca taaacaggcc ttcgacctga tatccctgtt gttgtaacag ccaggcagaa
    24361 acggaggaat cgacaccgcc ggacatgccg acgattactt tttttgcggt ttcagacatt
    24421 ggatcactca cgacattgaa cttcaaggcg gcgtattcta tcacgcagcc ttttagatga
    24481 caccctttgt aaaaggccag ttaaaatcgc caatcatctc cagcggatag cgttgcccgc
    24541 tttgataaca acgaatactt tccgccacca gcggcgaacg aagatttgac gcctgtaaaa
    24601 tttcttcggc gctgacccaa cggcagcagt cgatatcgct gtcatgaggc tgcgtcgggc
    24661 atatttgctc aagctcaatg gcaaagagga aacgcaaaaa cggcgtttta tcgggcgcaa
    24721 tccactgatg catacgaata aagtgttgcg gctgcgcgct aatgccggtt tcttcccaca
    24781 gctcacgggc ggcggcttcc actaaggttt catcggcttc caggtgcccg gcaggttggt
    24841 tccataacgc tttaccatta atcgtctctt caacgactaa aaatttgcct tctgcgtgca
    24901 ccacgcaagc aacggtaacg tgcggtttaa acattttgca tccttaatct gtcgcgtctc
    24961 gccattcgcc attggcaaga ttatccaaag agtaatcccc catcgcatag cgaatcagtc
    25021 gcagcgtggg gaaaccaaca tgggcggtca tgcggcgcac ctggcgatta cgtccttcat
    25081 ataaggtgat cttcagccag ctggtgggaa tacttttgcg ctcacgaatt ggtggattcc
    25141 gcggccataa ccacgcgggt tcttcaacca gctccgcgcc tgcgggcagg gtagggccat
    25201 catttaaggt tacgccattg cgcaaggctt caagtgcgtc ttgtgtggga ataccttcca
    25261 cctgcacata atagattttt ccggtgcgtt tacccggctg ggttaaacgc gcctgcaacg
    25321 cgccgttatt ggtcagcacc agtaaccctt cgctgtcgcg gtcgagacga cctgccgcat
    25381 acaccccctg aaccgggatg aattctttta atgttttgcg tccggcttca tcggtgaact
    25441 gcggaagaac atcgtagggt ttattgaaca ggatcacacg cgtgggctgg ttgtcaggtt
    25501 tacgcctggt agaacgttgc gagctgaatc gcttaacctg gtgatttcta aaagaagttt
    25561 tttgcatggt attttcagag attatgaatt gccgcattat agcctaataa cgcgcatctt
    25621 tcatgacggc aaacaatagg gtagtattga caagctaatt acaaatcatt aacaaaaaat
    25681 tgctctaaag catccgtatc gcaggacgca aacgcatatg caacgtggtg gcagacgagc
    25741 aaaccagtag cgctcgaagg agaggtgaat ggaaagtaaa gtagttgttc cggcacaagg
    25801 caagaagatc accctgcaaa acggcaaact caacgttcct gaaaatccga ttatccctta
    25861 cattgaaggt gatggaatcg gtgtagatgt aaccccagcc atgctgaaag tggtcgacgc
    25921 tgcagtcgag aaagcctata aaggcgagcg taaaatctcc tggatggaaa tttacaccgg
    25981 tgaaaaatcc acacaggttt atggtcagga cgtctggttg cctgctgaaa cccttgatct
    26041 gattcgtgaa tatcgcgttg ccattaaagg cccgctgacc actccggttg gtggcggtat
    26101 tcgctctctg aacgttgccc tgcgccagga actggatctc tacatctgcc tgcgtccggt
    26161 acgttactat cagggcactc caagcccggt taaacaccct gaactgaccg atatggttat
    26221 cttccgtgaa aactcggaag acatttatgc gggtatcgaa tggaaagcag actctgccga
    26281 cgctgagaaa gtgattaaat tcctgcgtga agagatgggc gtgaagaaaa ttcgcttccc
    26341 ggaacattgc ggtatcggta ttaagccgtg ttcggaagaa ggcaccaaac gtctggttcg
    26401 tgcagcgatc gaatacgcaa ttgctaacga tcgtgactct gtgaccctgg tgcacaaagg
    26461 caacatcatg aagttcaccg aaggcgcgtt taaagactgg ggctaccaac tggcgcgtga
    26521 agaatttggc ggtgaactga tcgacggcgg cccgtggctg aaagttaaaa acccgaatac
    26581 cggcaaagag atcgtcatta aagacgtgat tgctgatgca ttcctgcaac agatcctgct
    26641 gcgtccggct gaatatgatg ttatcgcctg tatgaacctg aacggtgact acatttctga
    26701 cgccctggca gcgcaggttg gtggtatcgg tatcgcccct ggcgcaaaca tcggtgacga
    26761 atgcgccctg tttgaagcca cccacggtac tgcgccgaaa tatgccggac aggacaaagt
    26821 aaacccaggc tctattattc tctccgctga gatgatgctg cgccatatgg gttggactga
    26881 agcggctgac ctgattgtta aaggtatgga aggcgcaatc aatgccaaga ccgtaaccta
    26941 tgacttcgaa cgtctgatgg aaggcgctaa actgctgaaa tgttcagagt ttggtgacgc
    27001 gatcatcaag aatatgtaat cactacatgt gttaaatatt gaaacgggcg tataacacgc
    27061 ccgttgtttt atgatgatgt aaaatcttcc ccaaaacttt ccccaaaacc cttccccaaa
    27121 actggctatt ttctatgctg ttttgatatc tacgataatc cagtctttac cacgatcatc
    27181 attgtatcgg tcggtcattt ttctggattt atggcctaac aacttttgcg tatccagacc
    27241 ctgttcccga tataaccgtt ctgacagaga tcgctgctca tgaaatgtgg gcgcagttcc
    27301 ttgctcccat tttatgccac atttttcccg ggccttttta aaagccgttg tcagagtatt
    27361 tgcagaaacc tggtctcctc tgtttgcttg agaggtagtg tgacggtaat ggaccagata
    27421 tttactaaca acagcatccc tgcactgaga tataacttca cgaagggtaa tattcagagc
    27481 atcgcatttc aggttaagcg gaatagcaag ttttgaaccg gttttttcct gagtaatgtg
    27541 caacatgtcg tcccatatat cagagaattt caaattgcag atatcgccta aacgttgtcc
    27601 agtaacaaga gcaagtagca tgccgcattt taaatagggc tgccgtctgc ttacgctgtc
    27661 aaatattgcc tgccattcgg gcagtgacaa tctttggcgg tttactcgat ttcgcggttg
    27721 ttttgttgcc tgcgctgggt taaatcctgg cggaacatgt cctgcgtgtt gtgcttcttt
    27781 gaagacgtcg atcaacacca ttctcacgac ttgcgccatc ctgttatgac cttcagcctt
    27841 tacagcatca attatttcgg caatatcaag tgcggtaata tccttgaggt gttgcattcc
    27901 acaatgctca cggaaaagac gaatgggttt gcctttttgc cgataggagt tgggtcttag
    27961 ttcattatgt tgcagcctgt cctcttggat agaaatatat ttatcaagcc attctgtcac
    28021 cgtaatgtct gagcgcctgc ctttcattct ttccagacgc tcattgacgc ttaatatttg
    28081 tctggtacgt tgttcagcaa taatggtatt tgcttcagta gcaacttgtt ttgcttcatt
    28141 ctcatcagtt cctaagctat gaaaacgacc ggatagtgga tgtttgtatt gccaatatac
    28201 ctttccggtt cgcttatcta atttgcaata taaattgggt atagagattt tgtgagatcg
    28261 gggtctagca gccatcagcg attatccttt ggagttttgg gtttgcgttt attgggagtt
    28321 gcggttctgc aagcgttcct acaaaacggg aatttcggtc aatcatccag tagcgaccaa
    28381 cttttatagc gggtggggcc atcattttcc cttgcgcgta ttttttcaga actcgctcac
    28441 ttggtgctaa gtccccaaat tcttctttag cccagtcctg taaagtgatt agtcgagaca
    28501 tttgtcctcc tcttagctgc tgagggagtt tgtgaccgat atatctgaca tgatattaag
    28561 ctcatggcag gtacatctct tgactggtca tagagataaa tttaatgctg agaaatgcag
    28621 tattgaattt atcaattttt ctatttcctg cgcatgtcac gtaacttctt aatgtgttct
    28681 gccgtttcga tctcttctgc tatccgatct gcatcagctt tattcacagg ttcaaagtca
    28741 tgattaaagc ggaacatgct ggcgatacat gttctgcctt ttcggatgta gtgaactttg
    28801 ttgtgggtag aacgcaggat tttgcaggga gtgccgtggt ggtcgacgta ccaggtgtta
    28861 gggtcaatca ctctgaacat tcttgacctt gtgttgtgcg gattgatatt cagtgctgat
    28921 attcaccttt atagcgaaca cctttaccgg tttatcgcca aagtgcggat gtgtgattgt
    28981 cttcacttca tatccgtcat acggaacatc aattctgcga ctggaatcgt cgcgcttcgg
    29041 atatcccttt gtgataatca ggcggtcata ttcccggaac ataattcgct tattccagta
    29101 gtcattacac aagcgatact cttccgtttt ctctccgcga atcatggcat cgaagtattc
    29161 acttttaaca gcaagttgca ggttagccat cacttaatcc ccctttgttt gcggataagc
    29221 tccagatctt gctggcaact ggcgcaagtc cgacaaccct gaacggccag gcgtcttcgt
    29281 tcatctatcg gatcgccaca ctcacaacaa tgagtggcag atacagccag gtagttcagg
    29341 cggcgcattt ttattgctgt gttgcgctgt aattcttcta tttctgatgc tgaatcaatg
    29401 atgtctgcca tctttcatta atccctgaac tgttggttaa tacgcttgag ggtgaatgcg
    29461 aacaataaaa aaggagcctg tagctccctg ataattttgc ttttcatgtt catcgttcct
    29521 taaagacgcc gtttaacatg ccgattgcca ggcttaaatg agtcggtgtg aatcccttca
    29581 gcgttaccgt ttcgcggtgc ttcttcagta cgctacggca aatgtcattg acgtttttat
    29641 ccggaaactg ctgtctgact tttttgattt cagaattagc ctgacgggca atgctgcgaa
    29701 gggcattttc ttgctgaggt gtcactgaac aagccccatg tcggcaagca taagcacaca
    29761 gaatatgaag cccgctgcca gaaaaatgca ttcagtggtt gtcatacctg gtctctctca
    29821 tctgcttctg ctttcgccac catcatttcc agcttttgtg aaagggatgt ggctaacgta
    29881 tgaaattctt cgtctgtttc tgctggtatt ggcacaaacc tgactccaat ttgagcaagg
    29941 ctatgtgcca aatcaatact cgttcttaac tcaacaggag atgctttgtg cataccgccc
    30001 cccgtttatt atttatctcc tcagccagcc gctgggcttt cagcggattt cggataacag
    30061 aaagaccgtg aaatacccag cctcgctttg taacggagta gacgaaagtg atcgcgccta
    30121 cccggatatt atcgtgagga tgggtcatcg ccattgctct ccaaatacaa aaccaatttc
    30181 agccagtgct tcgtccattt tttcgatgaa ctccggcacc atctcgtcaa aactcgccat
    30241 gtacttttca tcccgctcaa ccacgacata atgcaggcct tcacgcttca ttcgtgggtc
    30301 atagttggca aagtaccagg catcttttcg tgtcacccac atgctgtact gcacctgggc
    30361 catgtaagcc gactttatgg cctcgaaacc accgagccgg aacttcatga aatcccggga
    30421 ggtaaacggg catttcagct caaggccatt gccgtcactg cataaaccat cgggagagca
    30481 ggcggtgcgc atactttcgt cgcgatagat gatcggggat tcagtaacat tcacgccgga
    30541 agtgaattca aacagggttc tggcgtcgtt ctcgtactgt tttccccacg ccagcgcctt
    30601 agcattaact tccggagcca caccggtgca aacctcagcc agcagggtgt ggaagtagga
    30661 cattttcatg tcaggccact tctttcctga gcggggcttt gctatcacgt tgtgaacttc
    30721 tgaagcggtg atgacgccga gccgtaattt gtgccatgca tcatccccct gttcgacagc
    30781 tctcacgtcg atcccggtac gctgcaggat aatgtccggt gtcatgctgc caccttctgc
    30841 tcagtggctt tctgtttcag gaatccaaga gctttcactg cttcggcctg tgtcagttct
    30901 gacgatgcgc gaatgtcgcg gcgaaatatc tgggaacaga gcggcaataa gtcgtcatcc
    30961 catgttttgt ccagggcaat cagcagagtg ttaatctcct gcatggtttc atcgttaacc
    31021 ggagtgatgt cgcgttccgg ctgacgttcc gcagtgtatg cagtattttc gacaatgcgc
    31081 tcggcttcat ccttgtcata gataccagca aatccgaagg ccagacgggc acactgaatc
    31141 atggctttat gccgtaacat ccgtttggga tgcgactgcc acggccccgt gatttctctg
    31201 ccttcgcgag ttttgaatgg ttcgcggcgg cattcatcca tccattcggt aacgcagatc
    31261 ggatgattgc ggtctttgcg gtaaatccgg cacgtacatg attcattgtc ctgctcaaag
    31321 tccatgccat caaactgctg gttttcattg atgatgcggg accagccatc aacgcccacc
    31381 accggaacga tgccgttctg cttatcaggg aaggcgtaaa tttctttcgt ccacggatta
    31441 aggccgtact ggttggcgac gatcagcaat gcgatgaact gcgcatcgct ggcatcacct
    31501 ttaaatgccg tctgacgaag agtggtgatc agttcctgtg ggtcgacaga atccatgccg
    31561 acacgttcag ccagcttccc agccagcgtt gcgagtgctg tactcatccg ttttatacct
    31621 ctgaatcaat atcaacatgg tggtgagcaa tggtttcaac catgtaccgg atgtgttctg
    31681 ccatgcgctc ctgaaactca acatcgtcat caaacgcacg ggtaatggct tttttgctgg
    31741 ccccgcagcg ttgcaaatga tcgatgcaga gtgattcaaa caggtgctgt ggaagacctt
    31801 tttccatgtc gtctgccagt tctgcctctt tctcttcacg ggcgatctgc tggtagtgac
    31861 gcgcccagct ttgagcctca agacgatcct gaatgtaata agcgttcatg gctgaactcc
    31921 tgaaaatggc tgtgaaaata tcgcctgcga aatgccgggc tgattaggta aacaggaaag
    31981 gggattagtg attcaggccg ttgccgcgtc cgtcgagaaa aacttccacg agcaaatcac
    32041 gggtataagt gcgctcgatg ccgcgatgca gataaagccg tccgcgtaaa ttagctgatg
    32101 cagtccaggt accatctttg tgtttgacca gcattcctgg catgaccgca ccgcgattaa
    32161 cggtctgcgt tccgtaatgt tgatgaacca taaaaactcc tgcccgtaag ctgggctgct
    32221 gaacatatag agacttctgc gcgtattcag gcggtggatg gccgccggtt gtcataacta
    32281 agccgcctcg ttgaagcgac taaggtatga aatgttgagt taatttcagc tggtcacacc
    32341 gacgttcacg cgtccgtttc acccctcgca ctccccgaag cctgctgaaa ttcaaactgc
    32401 ggatctaagc ggtcatcgca acggtgaatc aggtagttgc cgtatcgttg tgttgttgcg
    32461 atgaacttat ttaaaactat agttgtttta tcgtcaacaa caaaagttgt tttattggtt
    32521 gttttagata taactggttg tatttaggat ggatttattt tgtgacttga atcgcatagc
    32581 gataactgaa gcgaggttat ggtggttttt ttaacggtgt gtgtgatgag gggagggcaa
    32641 aagaaaaccc ggcacggtga ccgggattct tacgccgtta ggtaaagata ttattgcggt
    32701 ggcttaatat tactacctag agcaaagata ggaattagtt ctttactgaa tgagcacaat
    32761 gcccagttga taatttttaa ttggtactac ccatgcttcc tatatgtctg cggcatgctc
    32821 ccaataacct taccgaagat gaacacccgg ttcatctcgt ctttctcgat cgggtcccac
    32881 ggtgagtagc ttttgttatc agagatgacc agcagcttat ccttcatcat ttgcaggcgc
    32941 tttacatggg ctgtgtcgtc gtacagaaac gcatagatac catcaccgtc gaaagattta
    33001 actgtgatat caacgaacag cagatcacct ggttcgatcg ttcctgacat gctgtcacca
    33061 cgcacgttaa tgatgcggat attttccgcc ttcctaccat cgaacatgtg acgagcatcg
    33121 tcaaacgagt actcaaccga gcgtagaact tctacaaact cacggttgat gactcccggc
    33181 ccagcactga cttctatatc aagaacgtca atcttgaagt atttggaatg gctgacagtt
    33241 gattgtattg gttgcactgt actgtctgac atatttccaa cgccagaaga taaccattct
    33301 gcgcgcacac ccaaagcgtt cgcgatctcc acgattttag ttgtttgatt agctttccct
    33361 gtttcgattt tctgaatagc agcctggcta accccgacca aatccccaag cgccttttgt
    33421 gtaaggcctc gcgctaatct ggcttcttta agtctttctg agagtgttgt tttcatagtc
    33481 caaatgtaca accaaggttt tattccatca aacgaaaatg gttgttgact aaaaacaacc
    33541 atagttttaa tcttgattca aattaaccac ggaggttgtt atgaacccag ctatcaaaac
    33601 agcgatcaat atcgttggtt cacaaaagaa actgggcgct gcttgcgaag tttcacagca
    33661 ggccgtctat aagtggcttc acaacaaagc aaaggtatcc cctgaacatg tcggcagcat
    33721 tgttacggct actggtggag tagtgaaggc ataccagatt cgcccggatc ttccgaagtt
    33781 gtttccacac accgaaaaga acgcagctta aatttccatt tcacgctctt taacaataag
    33841 caatcaactt aacagtcaat tcaaactaaa ggagtcaatt atgcaaccac ttacatacca
    33901 acagactagc ggatttagcc cgactgcggt gataaatcgt tctcaaacaa aacaggtgcc
    33961 aggccacgaa aaaatccgtg atgccgtccg cgcctggtcg gctgtagata atcaggatgt
    34021 cgttgccaca ctcattgtga atgagtatct ggagcagggc ggcggcacca tcgatttccc
    34081 tgatgatgtc agccgtgcac gccagaagct gttccgcttc ctcgataaca aattcgattc
    34141 tgaaaaatac cgaaataacg tgcgtgaact gaccccggca attctggcgg tactaccgct
    34201 ggaatatcgc ggttacctgg ttgagcagga tagcttcatg gctaggttgg ctgaaatgga
    34261 aaaggaactc agtgaggcaa aacaggctgt cattctcaac gcaccacgcc accagaaact
    34321 gaaggaaatt agtgaaggta ttgtgtcgat gtttcgtgtg gacccagatc tggctggtcc
    34381 attgatggcg atggttacta ccatgctggg ggcgatatga caggttcaga aatggcgaaa
    34441 gccggtctgc tggaacagaa ccgactttca ggtgcaaatc gtaacacact cattgcggga
    34501 ggaattatgg caaacactgc tgagatattc aattttccag tgccggatgc ggcacaaaag
    34561 gagccgcgcg tggcagatct cgatgatggt tatacgcgca ttgcaaatga gttgctggaa
    34621 gctgtgatgc tggccggatt aacacagcac cagcttctgg tctttctggc tgtcatgcgc
    34681 aaaacatatg gctttaataa aaaactggat tgggttagca acgagcaact ttccgaatta
    34741 accgggatat tgccgcacaa gtgttctgct gcaaaaagtg ttctggtaaa gcgtgggatt
    34801 tttattcaga gcgggcggaa taccggcatt aataatgtgg tcagtgaatg gtcaacatta
    34861 cccgaatcag gtaagaaaaa taaagtttac ctgaaagagg taaatttacc tgaatcaggt
    34921 aaaaaaagtt tacccaaatc aggtaaaggc gtttacccga atcaggtaaa cacaaaagac
    34981 aaactaacaa aagacaatat aaaacctttt tcgtccgaga attctggcga atcctctgac
    35041 caaccagaaa acgatcttcc tgtggtgaaa ccggatgctg caattcagag cggcagcaag
    35101 tgggggacag cagaagacct gaccgccgca gagtggatgt ttgacatggt gaagaccatc
    35161 gcgccatcag ccagaaaacc gaattttgca gggtgggcta acgatatccg cctgatgcgt
    35221 gaacgtgacg gacgtaacca ccgcgacatg tgcgtgctgt tccgctgggc atgccaggac
    35281 aacttctggt ccggtaacgt gctaagtccg gccaaactcc gcgacaagtg gacccaactc
    35341 gaaatcaacc gtaacaagca acaggcaggc gtgacagcta gcaaaccaaa actcgacctg
    35401 acaaacacag actggattta cggggtggat ctatgaaaaa catcgccgca cagatgatta
    35461 actttgaccg tgagcagatg cgtcggatcg ccaacaacat gccggaacag tacgacgaaa
    35521 agccgcaggt acagcaggta gcgcagataa tcaacggtgt attcagccag ttactggcaa
    35581 ctttcccggc gagcctggct aatcgtgacc agaacgaact gaacgaaatc cgccgccagt
    35641 gggttctggc tttccgggaa aacgggatca ccacgatgga gcaggtgagc gacggaatgc
    35701 gtgttgcccg tcggcagaat agaccatttc tgccatcacc cgggcagttt gttgcatggt
    35761 gccgggaaga agcatccgtt accgccgggc tgccaaacgt cagcgagctg gttgatatgg
    35821 tttacgagta ttgccggaag cgtggtctgt atccggatgc agagtcttat ccgtggaaat
    35881 caaacgcgca ctactggctg gttaccaacc tgtatcagaa catgcgggcc aatgcgttga
    35941 ctgacgcgga attacggcgc aaggctgccg atgaactggc ctgtatgacc gcgcgaatta
    36001 accgtggtga ggctatacct gaaccagtaa aacaacttcc tgtcatgggc ggtaggcctc
    36061 taaatcgtgc acaggctctg gcgaagatcg cagaaatcaa agctaagttc gggctgaaag
    36121 gagcgatgaa atagagctaa agtattagct taaaaataaa gtatacctag cgaatataat
    36181 ctaggactag ttgtaacgcc cgaaatgatt gattgcgtga gcaacaaaat ttttcttcca
    36241 ttgttgtgaa atcatttagc cataaagttt atgcagagat tt
//
LOCUS       DAPOXO010000049        35993 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPOXO010000049 DAPOXO010000000
VERSION     DAPOXO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.049"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            332..916
                     /locus_tag="ROH59_002839"
     CDS             332..916
                     /locus_tag="ROH59_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4805298.1"
                     /translation="MSKKLGFALSGLMLAMVAGSASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEISEGVLDTTVGAKAKPFSITVDCSKANPAPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINTPSDGVNIALHNIEGSTIKQVKINNPGDIYSKALDATSKS
                     ATYDFKASYVRADASLAATAGYVKTNTAYTVTYQ"
     gene            1013..1753
                     /locus_tag="ROH59_002840"
     CDS             1013..1753
                     /locus_tag="ROH59_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HDX4805299.1"
                     /translation="MFFNTKYTAALCFATCVAFSSSAIADIVISGTRVIYKSDQKSVN
                     IRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTASS
                     VLPKDRESVFWFNVLEVPPKPDAATVANQSLLQLAFRTRIKLFYRPEALKGNPSEAPL
                     ALKWSWSGSEGKAALRVANPTPYYVSFSSGDLEASGKRFPIDVKMIAPFSDEVMKVTG
                     LNGKANSAKVHFYAINDFGGAIEGNASL"
     gene            1788..4388
                     /gene="htrE"
                     /locus_tag="ROH59_002841"
     CDS             1788..4388
                     /gene="htrE"
                     /locus_tag="ROH59_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HDX4805300.1"
                     /translation="MTIKPTKNYHNHLTRIATFCALLYCNGAFCAELVEYDHTFLMGQ
                     NASNIDLSRYSEGNPAIPGVYDVSVYVNDQPVINQSITFVAIEGKKNAQACITLKNLL
                     QFHINSPDINSEKAVLLARDEALGNCLNLTEIIPQASVRYDVNDQRLDIDVPQAWVMK
                     NYQNYVDPSLWENGINAAMLSYNLNGYHSETPGRKNDSIYAAFNGGMNLGAWRLRASG
                     NYNWMTDSGGNYDFKNRYIQRDIASLRSQFIIGESYTTGETFDSVSIRGIRLYSDSRM
                     LPPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIVT
                     IEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVLKDDIQDEPNLFQASYYYGLNN
                     YLTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTHSNVRIPDDKTYQGQSYRVSWN
                     KLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKSMRNYSRMKNQVT
                     VSINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYSIGYSNSASWGSYSISAQRSWN
                     EDGDADDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQMSSDFKGNNQLNVSSSGYSDNA
                     RVSYSVNTGYTMNKASKDLSYVGGYASYESPWGTLAGSVSANSDNSRQVSLSTDGGFV
                     LHSGGLTFSNDSFSDSDTLAVVQAPGAQGARINYGNSTIDRWGYGVTSALSPYHENRI
                     ALDINDLENDVELKSTSAVAVPRQGSVVFADFETVQGQSAIMNITRSDGKNIPFAADI
                     YDDQGNVIGNVGQGGQAFVRGIEQQGNINIKWLEESKPVSCLAHYQQSSEAEKIAQSI
                     ILNGIRCQIQ"
     gene            4405..4977
                     /locus_tag="ROH59_002842"
     CDS             4405..4977
                     /locus_tag="ROH59_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414680.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4805301.1"
                     /translation="MIKTTPHKIAILMGVLLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKITNKTTESQADFKLVASGCSSGISWIDTTLTGNAL
                     SSSSKLIIPLSGDLSSTTSNIGMGFKKRTTDDATFLQPNNSADKIRWSTEEMQPDKGL
                     EMTVALRETAAGQGVPGIFRALATFNFIYQ"
     gene            4992..5594
                     /gene="yadL"
                     /locus_tag="ROH59_002843"
     CDS             4992..5594
                     /gene="yadL"
                     /locus_tag="ROH59_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HDX4805302.1"
                     /translation="MTFKNLRYGLSSSVVLAASLFSVPSYAATDSIGLTVITTVEMGT
                     CTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKRA
                     TCEGTANDGAGFANGSTATDKASAVAVEVWSTETPATGRATQFSCVTPASQEVTISTA
                     ANAVVYYPMSARLVVEKNKTVSNVTAGKFSAPATFTVTYN"
     gene            5621..6217
                     /locus_tag="ROH59_002844"
     CDS             5621..6217
                     /locus_tag="ROH59_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4805303.1"
                     /translation="MHPTQRKLMKRIILFLSLLFPITCPAIAGQDIDLVANVKNSTCK
                     SGISNQGNIDLGVVGVGYFSGNVTPESYQPGGKEFTVTVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEVTTGAKNVGVVLFSIQDPANIFNVLSSAGNSRSIYPVMTS
                     ALNNSSWKFYARMQKIDPALDVISGQVMSHILVDVHYE"
     gene            6269..7522
                     /locus_tag="ROH59_002845"
     CDS             6269..7522
                     /locus_tag="ROH59_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001462196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin"
                     /protein_id="HDX4805304.1"
                     /translation="MKTFFKYFVFLVLSCSCFTAISKDTSFLVGNNAGVGDGNFNGPS
                     TAAQVTFRYASTTNNLVFYKPTQLGPTGVKLRWEQLDTASGGGFLYCNASDRANPDGL
                     MDIENAMADSGKTYGGHKLFKTSVPGLYYTLFIAKLWSAYSTKTTISDSGLYIGDTTP
                     QKFQWIITDPDLQHIGCDNAMRYDRFWAIGGVVHDLTIEFYTDTDFNPTTNQDVSLSS
                     NSTYLYAFKAYSPGSRVVDHSHHLYIDFDLLNVKLTNPTCFTAVLTGKSVSGSTVKMG
                     EYAPGQIKNGATPVPFDISLQNCVRVGDIETKLSSGKLGTENKQLLGNTLTGSGAAKG
                     VAVLIEGLANRKSALMILKPNDSTSVYKDNTGQAQDHDSDAIYPEDQGITYPLHFQAT
                     LKQDGNIAIEPGEFKATSTFQVTYP"
     gene            7635..8429
                     /gene="panB"
                     /locus_tag="ROH59_002846"
     CDS             7635..8429
                     /gene="panB"
                     /locus_tag="ROH59_002846"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDX4805305.1"
                     /translation="MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFAEEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAA
                     DRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            8441..9292
                     /gene="panC"
                     /locus_tag="ROH59_002847"
     CDS             8441..9292
                     /gene="panC"
                     /locus_tag="ROH59_002847"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDX4805306.1"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIIGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIIAIAGQELNEKGFRADDIQIRDADTLLEVSENSKRAVILVAAWLGDARLID
                     NKMVELA"
     gene            complement(9374..9571)
                     /locus_tag="ROH59_002848"
     CDS             complement(9374..9571)
                     /locus_tag="ROH59_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000404125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX4805307.1"
                     /translation="MEIKTRRETRQTLAQWFEEKGFQKGYKEGLQKVRLALRLLSKGM
                     SREDVAEMANLPLAEIDKMIN"
     gene            complement(9640..10560)
                     /locus_tag="ROH59_002849"
     CDS             complement(9640..10560)
                     /locus_tag="ROH59_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDX4805308.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLDIHLPAELRELCDLDTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGSTGYLHVVIEHQSKPDKKMTFRMMRYAIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNNPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEERGRQEVRQEVRQEVIQEVRQEVRQEF
                     ALRFLSKGMSREDVAEMANLPLAEVDKLIS"
     gene            10834..11214
                     /gene="panD"
                     /locus_tag="ROH59_002850"
     CDS             10834..11214
                     /gene="panD"
                     /locus_tag="ROH59_002850"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HDX4805309.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(11218..12447)
                     /locus_tag="ROH59_002851"
     CDS             complement(11218..12447)
                     /locus_tag="ROH59_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDX4805310.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYVFNFGLGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLVTWKDTQVYNAPSVGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMAQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRIDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVLYLSYPFGGFNDKAVKAAKEAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(12511..12951)
                     /locus_tag="ROH59_002852"
     CDS             complement(12511..12951)
                     /locus_tag="ROH59_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX4805311.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHETDSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSAFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            complement(13056..13826)
                     /locus_tag="ROH59_002853"
     CDS             complement(13056..13826)
                     /locus_tag="ROH59_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4805312.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            complement(13823..14749)
                     /locus_tag="ROH59_002854"
     CDS             complement(13823..14749)
                     /locus_tag="ROH59_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001621186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4805313.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRT"
     gene            14858..15520
                     /gene="can"
                     /locus_tag="ROH59_002855"
     CDS             14858..15520
                     /gene="can"
                     /locus_tag="ROH59_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HDX4805314.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            complement(15561..16097)
                     /gene="hpt"
                     /locus_tag="ROH59_002856"
     CDS             complement(15561..16097)
                     /gene="hpt"
                     /locus_tag="ROH59_002856"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDX4805315.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     gene            16303..18693
                     /gene="gcd"
                     /locus_tag="ROH59_002857"
     CDS             16303..18693
                     /gene="gcd"
                     /locus_tag="ROH59_002857"
                     /EC_number="1.1.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="HDX4805316.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLSVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEISGTLSADTTPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHKLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPIIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     gene            complement(18740..20290)
                     /gene="cueO"
                     /locus_tag="ROH59_002858"
     CDS             complement(18740..20290)
                     /gene="cueO"
                     /locus_tag="ROH59_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HDX4805317.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFNADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVNELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRNLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHSGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPATHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            20456..20803
                     /locus_tag="ROH59_002859"
     CDS             20456..20803
                     /locus_tag="ROH59_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HDX4805318.1"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            20909..21775
                     /gene="speE"
                     /locus_tag="ROH59_002860"
     CDS             20909..21775
                     /gene="speE"
                     /locus_tag="ROH59_002860"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDX4805319.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALP
                     QYLQDALASQPS"
     gene            21791..22585
                     /gene="speD"
                     /locus_tag="ROH59_002861"
     CDS             21791..22585
                     /gene="speD"
                     /locus_tag="ROH59_002861"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDX4805320.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTTEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(22623..22985)
                     /locus_tag="ROH59_002862"
     CDS             complement(22623..22985)
                     /locus_tag="ROH59_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HDX4805321.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(23160..25757)
                     /gene="acnB"
                     /locus_tag="ROH59_002863"
     CDS             complement(23160..25757)
                     /gene="acnB"
                     /locus_tag="ROH59_002863"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019080489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HDX4805322.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFDQLSQYTEKA
                     DGVIFQTAV"
     gene            26112..27875
                     /locus_tag="ROH59_002864"
     CDS             26112..27875
                     /locus_tag="ROH59_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HDX4805323.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASAGLYIKSRTVEAPVEAQSTQ
                     QTAPDISAVTLPATVSVPPVTPAVVKSAFSTAQIDQWVAPVALYPDSLLSQVLMASTY
                     PANVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQNIITTTKKVVPVNQPANAPATQSN
                     TVSTSSPVVAEPAPTVITIEPANPDVVYIPNYNPNVVYGSWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHDHHHHDDDDYHHHDGGHRDGNDWQ
                     HNGDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVTYHDQDMAKRFHQTDVNGGM
                     SATQLPALSRDSQRQAAASQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGNYDDFRE
                     FSRHQPLTQQQKDAARQRYQSASPEQRQAAREKMQTSPQNQQQRDAARQRIQSASPEQ
                     RQVFKEKVQQRPLNQEQRDNARQRVQSASPEQRPFFREKVQESRPQRLNDSNRTARLN
                     NEQRSAVRERLSERGARRLER"
     gene            complement(27946..29370)
                     /gene="lpdA"
                     /locus_tag="ROH59_002865"
     CDS             complement(27946..29370)
                     /gene="lpdA"
                     /locus_tag="ROH59_002865"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDX4805324.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(29578..31470)
                     /gene="aceF"
                     /locus_tag="ROH59_002866"
     CDS             complement(29578..31470)
                     /gene="aceF"
                     /locus_tag="ROH59_002866"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDX4805325.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAASAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            complement(31485..34148)
                     /gene="aceE"
                     /locus_tag="ROH59_002867"
     CDS             complement(31485..34148)
                     /gene="aceE"
                     /locus_tag="ROH59_002867"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HDX4805326.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            complement(34309..35073)
                     /gene="pdhR"
                     /locus_tag="ROH59_002868"
     CDS             complement(34309..35073)
                     /gene="pdhR"
                     /locus_tag="ROH59_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HDX4805327.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     gene            complement(35529..35819)
                     /locus_tag="ROH59_002869"
     CDS             complement(35529..35819)
                     /locus_tag="ROH59_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDX4805328.1"
                     /translation="MYNFKDKIEDYTEREFIELLGEFTNPTGDNAQLKGEELDKYWDD
                     LEEHLTRITQHPLMSDLIYYPAKKGDDEPENILKIVKEWRRSQGLPLFKDSE"
BASE COUNT         9073 a         9304 c         8520 g         9096 t
ORIGIN      
        1 atataaataa attccgaaaa ataacctcac cctattgaaa ttaatacacc ctctcagtta
       61 caatcataat taatattatt ttttcgcccc cccaccccat ctcacataca atacttttcc
      121 cgctgtgtat attaactttt gcttaaaaat gaattaagtg gatatttaaa tttaaatgtg
      181 tacattattc tacttagtga tgaacagatg ttaaattcag taaatcttca cattcatcat
      241 taacaaacta atctcttttc ctctatcggg aatccctgcc tgaaagggcc caattgtagt
      301 taaactcatg gaatatgatt caaggatttt tatgtctaaa aaattaggtt ttgcgctctc
      361 tggtcttatg ctggcaatgg ttgcaggtag tgcttctgca gatatggacg gtggtcagtt
      421 aaatatcagt ggtctggttg ttgataatac ctgtgaaacc cgcgtagacg gcggtaataa
      481 agatggcctg atcctgctgc aaactgcaac cgttggagaa atctctgagg gtgtgctgga
      541 cactaccgtt ggtgctaagg ctaaaccatt cagcattact gttgactgta gtaaagctaa
      601 tccggcacca ggcagcacag caaaaatgac ttttggttca gtcttctttg gtaacagtaa
      661 aggaaccctg aataatgaca tgtcaattaa tactccatct gacggtgtta atattgctct
      721 gcacaatatt gaaggttcta ctattaagca ggttaaaatc aacaatcctg gcgatatcta
      781 ttccaaagca ctggatgcaa cttccaaatc cgcaacttat gattttaaag cgtcttatgt
      841 tcgtgcagat gcaagtctgg cagccacagc aggttatgta aaaactaaca ctgcatatac
      901 cgttacttat cagtaatcac ttccattcat attcataaat tgaatacata cagggaataa
      961 tattgatact ccatactatt tcctgttttt ttaactctac caggaatggt ttatgttttt
     1021 caacactaaa tatacagcag cattatgctt cgcaacctgt gtagctttta gctcgtcagc
     1081 tatagcagat atcgtaattt ccggtacacg cgtaatctat aaaagcgacc aaaaaagtgt
     1141 caacattcgc ctggaaaata aaggcaataa cccattactt gttcagagtt ggctggatac
     1201 tggtgatgac aatgctgagc ctggcagtat taccgtcccc tttactgcga ctccgcccgt
     1261 atcacgcatt gatgcaaaac gcggccaaac catcaaactg atgtacaccg ccagcagcgt
     1321 cctgccaaaa gacagagaaa gtgtgttctg gtttaacgta ctagaagttc ctccaaaacc
     1381 agatgccgca acagttgcaa atcaaagcct gctgcaattg gcatttcgca cacgtataaa
     1441 actgttctat cgcccggaag cattgaaggg gaatccctca gaagcaccat tagccctgaa
     1501 atggtcctgg tcaggttccg agggtaaagc agcattacga gtggccaatc caacccctta
     1561 ctacgtctct tttagcagtg gtgatttaga agccagcggt aaacgctttc cgattgatgt
     1621 gaaaatgatt gcaccattca gtgatgaagt catgaaagtc actggcctta atggcaaagc
     1681 aaattctgca aaagtgcatt tttacgccat taatgatttt ggtggtgcca ttgaaggtaa
     1741 tgccagtctg taatcaggca aggatataat tccgcaggaa gcataacgtg actataaaac
     1801 caactaaaaa ttatcacaat catctgaccc gtatcgccac gttttgcgcg ctgctgtatt
     1861 gcaatggtgc tttctgtgct gaacttgttg aatatgacca taccttcctg atggggcaga
     1921 atgcctcaaa tattgatctc agccggtata gtgaaggtaa ccccgctata ccgggtgtgt
     1981 acgacgttag tgtttatgtc aacgatcaac ctgttattaa ccaaagcatt acatttgtcg
     2041 caattgaagg aaaaaagaac gcacaagcct gtatcacact taaaaattta ttgcagttcc
     2101 atattaattc tcccgatata aacagcgaaa aagccgttct gcttgcccgg gatgaagctc
     2161 tcggcaattg cctcaatttg acggaaatta tccctcaggc ttccgttcgt tatgacgtta
     2221 acgatcaacg tctggatata gacgttcctc aggcctgggt aatgaaaaat taccaaaact
     2281 atgttgatcc atcgttatgg gaaaatggca ttaatgcagc catgttgtca tacaacctca
     2341 acggatatca tagtgaaacc cctggtcgaa aaaatgacag catttatgct gcttttaacg
     2401 gtgggatgaa tttgggtgca tggcggctgc gtgcctcagg caactacaac tggatgaccg
     2461 attctggcgg taattatgat tttaagaatc ggtatataca gcgtgatatc gcctcactac
     2521 gctctcaatt cattattggt gagtcttata cgacgggcga aacctttgat tccgtcagta
     2581 tccgaggcat tcgcttatac agtgacagcc gcatgttgcc tccgacatta gccagctttg
     2641 cgcctatcat tcatggcgtt gccaatacca acgccaaagt cactattacg caaggtggct
     2701 ataagattta tgaaacgacg gtgccgccag gcgctttcgt cattgatgat ctgagtccat
     2761 cagggtacgg cagtgatctt attgttacca tcgaagaatc cgatggctca aagcggacat
     2821 tctcgcaacc tttttcatcg gtcgttcaaa tgttacgccc tggcgttgga cgttgggata
     2881 ttagcggcgg ccaggtctta aaagatgata ttcaggatga gcctaattta tttcaggcca
     2941 gctactacta cggtctgaat aactatctga cgggttatac cggtattcag attaccgata
     3001 ataactatac cgctggtttg ttaggtcttg gtctgaatac ttcggtcggt gcattttctt
     3061 tcgatgtgac tcactccaat gttcgtatac cggatgataa aacataccag gggcaaagtt
     3121 atcgtgtttc ctggaacaag ttattcgaag aaacaagtac ttcactgaat atcgcggcct
     3181 atcgctattc gacacagaat tatcttggtc ttaatgatgc actaactctg attgatgaag
     3241 tgaaacatcc agaacaagat cttgaaccga aatccatgcg taattactcg cgcatgaaaa
     3301 atcaggttac agtcagtatt aaccaaccgt tgaaatttga aaaaaaagat tacggttctt
     3361 tttatctttc tggtagttgg tccgattact gggcttccgg acaaaatcgt agcaattact
     3421 ccattggcta cagtaacagt gcatcctggg gcagctacag catcagtgca cagcgttcat
     3481 ggaatgagga cggcgacgct gatgatagcg tttatctcag tttcaccatt cctattgaaa
     3541 aattacttgg cactgaacaa cgtacttcag gtttccagag tatcgatact caaatgagca
     3601 gtgactttaa gggtaataac caactcaacg tcagtagcag tggctatagc gataacgctc
     3661 gcgtcagtta tagcgtgaat actggctata cgatgaataa agccagcaaa gatttgagtt
     3721 atgttggggg ttatgccagc tatgaatcac cgtggggaac tctggcaggt tcagtttctg
     3781 caaacagcga taacagtcgt caagtttctc tcagcaccga cggtggtttt gtattgcata
     3841 gtggcggcct gaccttcagt aatgacagtt ttagcgactc cgatacactg gcggtagttc
     3901 aggctccagg tgctcaagga gcgcgaataa attatggcaa cagtactatc gatcgatggg
     3961 gttatggtgt caccagcgct ctttctcctt atcatgaaaa ccgtatcgcg ctggatatca
     4021 acgatcttga gaacgatgtt gaattaaaaa gtaccagtgc tgtagctgtg cctcgtcagg
     4081 gttctgtcgt ttttgctgat tttgaaaccg tgcaagggca atcagccatt atgaacatca
     4141 cacgtagtga tggcaaaaat attccatttg ctgcagatat ttatgatgac caaggcaatg
     4201 tcattggtaa tgttggacag ggtggacagg cttttgttcg tggtattgaa cagcaaggaa
     4261 atatcaacat taaatggctc gaagaaagta aacctgtaag ttgtcttgcg cattatcaac
     4321 aaagttcaga agcagaaaaa atagcgcaat ctattattct gaatggaatt cggtgtcaga
     4381 ttcagtaact acaagggacg tcaaatgata aaaacaacgc cacataaaat agcgatactg
     4441 atgggagtat tattatcacc ctcagtattt gcaacggata ttaatgttga gtttacagcc
     4501 actgtcaaag cgacaacctg taacatcaca cttactggta ataatgtcac gaatgatggc
     4561 aataataact acactttgag aatccctaag atgggcctgg ataagatcac gaataaaacg
     4621 acagaatctc aggctgattt taaactggtt gccagtgggt gcagcagtgg cattagctgg
     4681 attgatacca ctctgaccgg aaacgcatta tcaagctcat ccaagcttat tataccgctg
     4741 tctggtgatt tatcttcgac gacaagtaat atcggtatgg gtttcaaaaa acggactact
     4801 gatgatgcca ctttccttca acctaacaac agtgcggaca agatacgctg gagcacagaa
     4861 gaaatgcagc ccgataaagg tcttgaaatg actgtcgcgc tacgtgaaac cgcagcaggg
     4921 caaggcgtgc cggggatttt tcgcgccctg gcgacgttta atttcatcta tcaataagaa
     4981 ggataattaa gatgacattt aaaaatttac gttatggatt atccagcagt gtcgttttgg
     5041 ctgcctcatt gttcagcgta ccctcttatg cggcaactga cagcattggg ctgaccgtga
     5101 ttaccaccgt agaaatgggt acttgtaccg ctacattagt aaatgactct gatcaggaca
     5161 tttctgttgt tgattttggt gatgtatata tttctgaaat caatgccaag accaaagtaa
     5221 aaacattcaa actcaaattc aaagactgtg cgggtatccc caataaaaaa gcgcaaataa
     5281 aattaaccaa gcgagccaca tgcgagggga ctgctaatga cggtgcaggg ttcgcaaatg
     5341 gttccacagc cacagataaa gcaagtgccg tcgccgttga agtctggagc accgaaactc
     5401 cggcaacagg gagagcaaca caatttagtt gtgtgacacc agcatctcaa gaggtaacta
     5461 tttccactgc tgccaatgcg gttgtttatt acccgatgag tgctcgcctg gtcgttgaaa
     5521 aaaataaaac cgtaagtaat gtcactgcag gtaaattttc tgcacctgcc acatttacag
     5581 taacctataa ctaacagact gacagattca ggaactatat atgcatccca ctcaacgtaa
     5641 gctgatgaag agaataattc tgtttctgtc attactgttt cccattacct gtccagcgat
     5701 cgctggacag gatattgacc ttgttgctaa tgtaaaaaac agcacttgca aaagcggaat
     5761 cagtaaccag ggtaatattg atcttggtgt cgttggggtg ggatattttt caggtaatgt
     5821 tactcctgaa agctatcaac caggtggaaa agagttcact gtcactgtct cagactgtgc
     5881 attacaggga actggcgatg tgctaaatca gttacatatt gattttagag cccttagcgg
     5941 tgtcatggct gcaggctcca ggcaaatatt tgccaatgaa gtgacaaccg gggctaaaaa
     6001 tgtcggtgtc gttctctttt ccattcagga cccggccaat atattcaatg ttcttagttc
     6061 agcgggaaat tctcgttcaa tctatccagt aatgacttct gccctgaata attcgtcatg
     6121 gaaattttat gccagaatgc aaaaaatcga tcccgcgctg gatgtcatat ctggccaggt
     6181 gatgagtcat atattagttg atgtgcacta cgaataatat atcaaaacaa acgactgcta
     6241 ttatgacagc agcgaatagt gggtaatcat gaagacattc ttcaaatact ttgttttttt
     6301 agtactatcc tgctcttgct ttacagcgat tagtaaggat acaagttttc ttgttggtaa
     6361 caatgccggg gtaggcgatg gtaatttcaa cggcccgagc actgcggctc aggtcacttt
     6421 tagatatgca tcaacaacca ataatttagt tttttataaa cctactcaac ttggcccgac
     6481 aggtgttaaa ttacgctggg aacaattaga tacagccagc ggtggcggtt ttctttactg
     6541 taatgcctct gacagggcaa atccagatgg actaatggat attgaaaatg ccatggctga
     6601 ttctggtaaa acctatggtg gacataagtt atttaaaacc tctgtcccag gcttgtatta
     6661 cactctattt attgcaaaac tttggtctgc atattcaaca aaaacaacta ttagcgactc
     6721 tggtttatat attggagata ccacaccaca aaaattccag tggatcatca cagaccctga
     6781 tctacaacat atcggctgcg ataacgcgat gcggtacgat agattctggg ccatcggcgg
     6841 tgttgtacac gatcttacga ttgaatttta tactgatacc gattttaacc ctacaacaaa
     6901 ccaggacgta tcattgtcca gtaattcgac atatctttat gcgtttaagg cctacagtcc
     6961 cggttctcgt gttgttgatc acagccatca cctttatatc gactttgatc tactcaatgt
     7021 taaattaact aaccccacct gctttactgc tgtacttacc ggaaaatcag taagtggttc
     7081 gacggtaaaa atgggagaat atgcaccagg gcagattaaa aatggtgcta ctccggttcc
     7141 ttttgatatt tctctccaga actgtgttcg cgttggcgat atagagacaa agctatcttc
     7201 agggaagctg ggtacagaaa ataagcaact cctgggtaac actcttactg gaagcggcgc
     7261 agcaaaaggc gttgcggtat tgattgaagg attagcaaac agaaaaagtg ccctaatgat
     7321 actgaaaccg aatgattcaa cttctgttta taaagataat acgggtcagg ctcaggatca
     7381 cgattcagat gcaatttacc cagaagatca aggtataaca tatccacttc atttccaggc
     7441 gacgttaaag caagacggaa atattgctat cgaaccagga gaatttaaag ccaccagtac
     7501 tttccaggta acctatccct gataacattg tggcaccgtc tggtaatggc ggtgccacaa
     7561 tagataaatc attgccccca ccaatgtggc tgataaaatg ccagacagca cgacattact
     7621 tatcaggata cgttatgaaa ccaaccacta ttgcttcatt gcaaaaatgc aaacaagaaa
     7681 aaaaacgttt cgcgaccatc actgcttacg attatagctt cgcaaaactg tttgccgaag
     7741 aaggacttaa cgtcatgctg gtcggcgatt ctctgggcat gacggttcag gggcatgact
     7801 ccacgctacc ggttaccgtt gctgatatcg cctaccacac tgccgccgtg cgtcgcggcg
     7861 cgccaaactg ccttctgtta gcagacctgc catttatggc gtatgccacg ccggaacaag
     7921 cctttgaaaa cgccgcaacg gtaatgcgtg ccggagccaa catggtcaaa attgaaggcg
     7981 gtgagtggct ggtagaaacc gtacaaatgc tgaccgaacg tgccgttcca gtttgtggtc
     8041 atttaggcct aaccccacag tcagtaaata ttttcggtgg ctacaaagtc caggggcgcg
     8101 gcgatgaagc ggccgatcga ctgctcagcg atgcattagc cttagaagct gctggggcac
     8161 aactgctggt actggagtgc gtgccggttg aactggcgaa acgcattacc gaagcactgg
     8221 cgatcccggt tatcggtatt ggcgcaggca acgtcactga cgggcaaatc ctcgtgatgc
     8281 acgacgcgtt cggcattacc ggcggtcata ttcctaaatt cgccaaaaat ttcctcgccg
     8341 aaacgggcga catccgcgcg gctgtgcggc agtatatggc tgaagtggag tccggcgttt
     8401 atccgggcga agaacacagt ttccattgag gagtgacgtt gtgttaatta tcgaaaccct
     8461 gccgctgctg cgtcagcaaa tccgccgcct gcgtatggaa ggtaagcgcg tggcgctggt
     8521 gcccaccatg ggtaacctgc acgacggcca tatgaagctg gtcgacgaag ccaaagcccg
     8581 cgccgatgtg gtcgtcgtca gtattttcgt taacccaatg cagtttgacc gcccggaaga
     8641 tctggcacgt tatccacgga ccttgcaaga ggactgcgaa aagctgaaca aacgtaaagt
     8701 ggatttagtt ttcgcgcctt cggtaaaaga gatctacccg aacggtacag aaacccacac
     8761 ctatgttgat gttcctggtc tttccaccat gctggaaggt gccagccgtc cgggacattt
     8821 tcgcggcgtt tcgactattg tcagcaagct gttcaacctg gtccagccgg acatcgcttg
     8881 cttcggcgaa aaggactttc agcaactggc gctgatccgc aaaatggttg ccgatatggg
     8941 ctttgatatt gagattatcg gcgtaccgat tatgcgcgcc aaagacggtc tggcgctgag
     9001 ttcccgtaac ggttatctga cggcggaaca acgcaaaatt gcgcccggtc tgtacaaggt
     9061 tttaagttcg attgccgaca aattgcaggc tggcgaacgg gatctcgatg aaattattgc
     9121 cattgccggg caagaactga atgaaaaagg cttccgcgcc gatgatattc agattcgtga
     9181 tgccgacaca ttgctggaag tctctgaaaa cagcaaacgc gcagtgattc tggtagccgc
     9241 ctggcttggc gatgctcgcc tgatcgacaa caaaatggtc gaactggcgt aatgcttaac
     9301 tggcgctacg gctgatggcg ccagctattc attgccacgt tatctgtaag cgattattca
     9361 taacgcagac aacttagtta atcattttat caatctcagc aagaggtaaa tttgccatct
     9421 ctgcaacgtc ttcccgagac attcctttac tcagaagacg cagggccagt cttaccttct
     9481 ggagtccctc tttatatccc ttctgaaatc ccttctcttc aaaccactgc gccaacgtct
     9541 gcctggtttc tctccgtgtc tttatttcca tatgttccct taattatctg gtcagttaac
     9601 aataacaatt atctggctat aactgataat gcagataact tagctaatca gcttatcaac
     9661 ctcagcaaga ggtaaatttg ccatctctgc aacgtcttcc cgagacatcc ctttactcag
     9721 aaaacgcagg gcgaattcct gtcttacttc ctgtctaacc tcttgtatta cctcctgtct
     9781 tacctcctgt cttacctcct gccttcccct ctcttcaaac cactgcgcca gcgtcatcat
     9841 agactcccct cccgtttccc tgtctcgcaa cacaccataa aacaaatccg cttgttcagt
     9901 atgaccgcgt tgcagcatat agttttgcat ggcaactaac tgacttccgc tagtgtaccc
     9961 ttcgtcaatc agcgtgacca gttgctccag caataacatt aagtcgcgct ggcgaatatg
    10021 cttttgcagt agttcgagaa tcgcaatccg ccggtgctgc atgatttcgt catccggcgt
    10081 gatggtgata tccaccagcg ggaaagggtt gttgtaaacg cgtcgcgcca gctccggcga
    10141 gtaaaacata tcaaaccagc acattgagag cggataaggt gtggcctcgc cctgataaaa
    10201 cagaatcggc accaccagcg gcagcttatc gtgatccgcc tccagatgcc ggtgcatggc
    10261 ggcaatggca tagcgcatca tgcgaaaggt cattttctta tccggcttgc tttggtgttc
    10321 aatcacaaca tgcagataac ccgtactacc ctgcatctgt acggaataga gcacgtcagt
    10381 gctgtgccct ttcaggcttt cttcaataaa actccccgac tcaagatgca gcgtgtcgag
    10441 gtcacacagt tcgcgtagct ccgctggcaa atggatatcc agaaagtcgc gagccgtttc
    10501 cgcatgcatt aaaaattgtt taaacaccgc atcatgcggt gtggtactcg gtgcatccat
    10561 ctcccctgcc ttccgtgttg tcttgcgtga aggcagtatc cagtcaaggt gtgccgtcgt
    10621 cagccgcctc tttagtgttt accgagcagc gttcagataa atttcaattg gttacaggcg
    10681 ttacatggca cgcttcggca cggtacgcaa actgctgatg caaatgccgt cagatgagta
    10741 gacactaaac aaaaatcggg caatactgcg tgagaatttc ctcaaagcag gcatcgcctg
    10801 cttcgttaac gacagggtag aaaggtagaa gttatgattc gcacgatgct gcagggcaaa
    10861 ctccaccgcg tgaaagtgac tcatgcggac ctgcactatg aaggttcttg cgccattgat
    10921 caggattttc ttgacgcagc cggtattctc gaaaacgaag ccattgatat ctggaatgtt
    10981 accaacggca agcgtttctc cacctatgcc atcgcggcag aacgcggttc gagaattatt
    11041 tctgtcaacg gtgcggcggc ccactgcgcc agcgtcggcg atattgtcat catcgccagc
    11101 ttcgttacca tgccagatga agaagctcgc acctggcgac ccaacgtcgc ctattttgaa
    11161 ggcgacaacg aaatgaaacg taccgcgaaa gcgattccgg tacaggttgc ctgattgtta
    11221 tccctgcggc tggttactca ccagccgcga catcgtctcc agcgaatctg ttcttaagat
    11281 ataaagtcgt tttagtaaca acggattatc ccccggtttt actttgcctt tcatggtcgt
    11341 cacagccagg tgaaatccgg cttcttttgc tgccttcacg gctttgtcat taaatccgcc
    11401 aaatggataa gaaagataca aaacatgtgg attaaattgc gccagagcgc ggcgtgaacg
    11461 tgcaaaatca aacagaatat tgtgctcact acggctcagc aatataggcc gccgataacc
    11521 atctatccga tgcaaaaaat gagtatgtga ctggaaatca aatacatcgc gaatttcgtt
    11581 aagttcagaa acgctcataa attgcagcga ttttgggttc catttctgcg ggtgacgttt
    11641 gatgcgcgag gtaacaataa acgccgtcgc cttcatgcca tattgtttca acacaggata
    11701 cgcatagcgg ctcaccgact tgaggccatc atcaaaggta atcaccaccg ctcgcgcagg
    11761 gagattgatc ttattcttca cgtaaccttc cagctgcgcc atgctcagtg tcgcgtatcc
    11821 cctgtcgcgc agccaggcca tctggttatt gaaagcgcgt accgaggtgg tcgtcgaagt
    11881 atggcgaaaa cgggtgtttt cttcatcgcg caaaatatgg tgataggtta gcaccggcag
    11941 gccattatcg ggttgggcat ccagcgcgct gatataggcc agtcgatcgc caatacggat
    12001 ctgataccag gtttgattta acctgtcttt cagtttatgc aaaatcgggt agcgcaaatt
    12061 gtccgccagt actccaaatg gcgcactgcc cacactcggc gcgttataga cctgcgtatc
    12121 tttccaggta actaagttct gattactcag cggcttgttg aggtcaccca aaccgtcttc
    12181 aactttttgt cgcccctgaa ccggctcgag atgcccttta tcgataaacc ctttgccaag
    12241 gccaaaatta aatacgtaat aacttgcggc agtgggctcc acggcaatga tttgtccggc
    12301 ccgaatattc cccaccgtca ccatcttgtc accaatttgc gcccagaccg cggcattttc
    12361 gatggtttgc atataacggg caggtaacgc ggcactgaca cttgcggtaa acagcatcag
    12421 caggagaata acagcttgtt tgtacatgaa aaaataaccg agggtgaaac aacgctttta
    12481 ttgtagcaaa agcgtcatca gaatcgcggg ttaatactca tacaaattat gtttgaggac
    12541 gaaaggcgga tttttttgtt gctggtgcca aagactactc acctccggcg cacccagttc
    12601 gacaatacgc tcgcgaaacg ctgaactggt catggtttca cggcaagcca tcatctgttc
    12661 aattaacggt aacgtgacac cagaaatcac ttcgcaacgg gagtgtttgt ggcttaataa
    12721 tgaagccacg cggtacggtg gcgctccggc tatatcggtt aagaaaataa cgccttcacc
    12781 agagtccgtt tcatgcaagg catcgcacat catgcggctg agcatattag agcttaatcc
    12841 gcgccagaaa ttcacggccc ggcactgaag aagtgcccca tgttttttct ccagcgcatc
    12901 cagtatctct tgcgcccggt catcgtgaca ggtaattacc caacctaaca tcgccttcct
    12961 ccttagccga aaatcagtct accctgacca ttgttgataa agggtgatag ccgtcaaaac
    13021 tcctctcccc caaatccaga ggagaggaaa tagccttagc tacgcaaacc acgtccacgt
    13081 tggatcagcg accaacagat caaataaaac gccacaataa agaccaccag tacgccaaag
    13141 gtagtgacca gcggaacatc attgataccg aggaagccgt agcggaaacc actgatcata
    13201 taaacgattg ggttcaggtg cgacagccct tgccagaacg gcggcaacaa agtcagggag
    13261 taaaacaccc cgcccaaata cgtgagtggc gttaacacaa aggttggcac caggctgatg
    13321 tcatcgaacg ttttagcaaa cacgccgttc agcaaacccg caagggagaa tagcaccgca
    13381 gtgagcacca gggttaaggc aacgaatacc cacgaatgca cctgaaacgg cacaaaaaac
    13441 agtgaaattg ccgtcaccag aataccaaca aacagaccac gcgccacgcc accaccgaca
    13501 tatccggcaa taatgacatg agtcggaacc ggcgctacca gcagctcttc aatattacgc
    13561 tggaacttgg caccaaaaaa tgatgacgcg acgttagcgt aggcgttggt gatcaccgac
    13621 atcatgatca gccccggtac gatgaactgc atgtagctga agccatgcat atcgccaata
    13681 cgcgaaccaa tcaggttacc gaagataata aagtaaaggg tcatggtgat gactggcggc
    13741 accagcgtct gcacccagat acgcataaag cgatggatct ctttcgccca gatgcttttt
    13801 agcgccaccc agtaaagatg catcatgtgc gatctccttg tttttcatta accagtgaaa
    13861 caaacagctc ttccagacgg ttagctttgt tacgcatact taatacctga atgccctgct
    13921 cacttaactg cgtaaatacg ctgttgatgc cctgctcacg cagcacttca acttccagcg
    13981 tggcggtatc taccagtcga tactgatagc catcgagctt cggtaacgga cttttcggtg
    14041 cgagatcgag aataaaggtt tctgatttca gcttcgccag cagcgccttc atcgaagtat
    14101 tttccaccaa ctcaccgtgt tgaataatgc cgatattgcg gcacagcatt tctgcttctt
    14161 ccaggtagtg tgtggtgaga atgatggtgg tgcctttgtc gtttaaatcc ttcaaaaagc
    14221 cccacattga gcggcgaagt tcaatatcca cgcctgcggt cggttcgtcg agaatcagta
    14281 gtttaggttc atgcattaac gcacgggcaa tcattaaacg gcgcttcatc ccgccagata
    14341 acatacgcgc acgttcgttg cgttttcccc atagatcgag ttgtttaaga tacttttcgc
    14401 tgcgaatgta cgcttctttg cgctccacac cgtagtaccc tgcctgattc accacaattt
    14461 gctgcacggt ttcaaacggg ttgaagttaa attcctgtgg caccagaccc aactgacgtt
    14521 tagcgtttac gacatctttc tcgagatcgt aaccaaatac gctgacccgc ccggaggttt
    14581 tatttaccag agagctgata ataccgatag tggtcgattt tccggccccg ttcggcccga
    14641 gaagcgcata aaaatcaccc gcttcgacct gcaaatcgat tccacgaagc gcctgaacgc
    14701 cgcctggata ggttttttta agctgttgaa gttccagtgc aatggtcata aatttttact
    14761 taccttacgt tcttacactt tatctgtggt ttaaatcgtc ccggagttgc cctatattag
    14821 ccaaacgtaa ttatttggtt acaggtcgtt aacctccatg aaagacatag atacactcat
    14881 cagcaacaat gcactatggt caaaaatgct ggtggaagag gatcccgggt tttttgagaa
    14941 actggcacaa gcgcaaaaac cgcgctttct atggattgga tgttccgaca gtcgcgttcc
    15001 tgcagaacgt ttaaccggtc ttgagccggg cgaactcttt gttcaccgta atgttgctaa
    15061 cctggtcatt cacaccgacc tgaactgcct ttccgtggtt cagtatgcag tggatgtact
    15121 cgaagttgaa cacattatta tctgtggcca ctacggttgc ggcggcgtac aagccgcagt
    15181 tgaaaacccg gaactggggc ttatcaacaa ctggctgctg catatccgcg atatctggtt
    15241 caaacatagc tcattgctcg gcgaaatgcc gcaagagcgc cgtctggata ccttgtgtga
    15301 actgaacgtc atggaacagg tgtataacct gggccactcc accattatgc aatcagcgtg
    15361 gaaacgcggg cagaaagtta ccattcacgg ctgggcctac ggcattcacg acggcttgct
    15421 gcgtgatctg gatgtcacag cgactaaccg cgaaaccctt gagcaacgtt accgtcacgg
    15481 gatctccaac ctcaagctga aacacgccaa ccacaaataa aaatgccatg ccggatgcaa
    15541 cacatccggc aacttcacac ttactcgtcc agcagaatca ctttgccgat atacggcaga
    15601 tgacggtaac gctgtgcgta atcaatgccg taacccacca caaactcatc cgggatcgag
    15661 aaaccgataa attctaccgg gacgttcact tcacgacggg acggtttatc cagcagcgta
    15721 caaatcgcca acgacttcgg ttcgcgcagg cttaagatct cacgcacttt cgacagtgta
    15781 ttccccgagt cgatgatatc ttcaacaatc agcacgtcct tgccacggat atcttcatcc
    15841 agatctttga ggattttcac atcacgggtg gtggacatgc cgctaccgta gctggaggcg
    15901 gtcataaagt cgacttcatg agatacctga acttcacggc acaggtccgc cataaacata
    15961 aatgagccac gcagcagacc caccagcacc atatcgctgc cgctgtcttt gtaacgctca
    16021 gtaatctgac gacccagttc ggcgatacgc gctttaatct ccgcttcggg gatcattact
    16081 tctacagtat gtttcatatc tataaccata tgatttaaaa acaaatcact tcgcacgggc
    16141 aggttttggc accgcaacaa agcgcaagac acgcagtata ccagtaaaac tattcattcg
    16201 cggaatctgt taataaagct cgaattgtga tgacgatcac acatgttaaa acctataatt
    16261 aattgctact aaaatattaa tgaattgaaa tggtgtctct ttatggcaat taacaatacc
    16321 ggctcgcggc gattactcgt cacgctaaca gccctttttg cagcgctttg cgggctgtat
    16381 ctactcattg gcggaggctg gctggtcgcg attggcggct cctggtacta ccctatcgct
    16441 ggccttgtga tgctcagcgt cgcctggatg ctgtggcgca gtaaacgcgc cgcgctttgg
    16501 ctgtacgcag ccctgctgct cggcactatg atttggggcg tctgggaagt tggtttcgac
    16561 ttctgggcgc tgactccgcg cagcgacatt ctggtcttct tcggcatctg gctgatcctg
    16621 ccgtttgtct ggcgtcgcct ggtcattcct gccagcggcg cagttgccgc actggtggtc
    16681 gcactgctga ttagcggtgg tatcctgacc tgggccggat ttaacgatcc gcaggaaatc
    16741 agcggcacct taagcgccga taccacgcca gcagaagcca tctcccccgt tgccgatcag
    16801 gactggcctg cctatggtcg caatcaggaa ggtcaacgct tttcacctct gaaacaaatt
    16861 aacgctgata acgtccacaa gctgaaagaa gcctgggtgt tccgtactgg cgatgtgaag
    16921 cagccgaacg atccgggcga aatcaccaat gaagtgacgc caattaaagt gggcgacacc
    16981 ctttacctgt gtaccgcgca ccaacgtctg tttgcgctgg atgccgccag cggtaaagag
    17041 aaatggcatt acgatcctga gctgaaaacc aacgagtcct tccagcatgt aacctgccgt
    17101 ggcgtctctt atcatgaagc caaagcagaa actgcttcgc cggaagtgat ggcggattgc
    17161 ccgcgtcgta tcattcttcc ggtcaatgat ggtcgtctga ttgcaattaa cgctgaaaac
    17221 ggcaagctgt gcgaaacctt cgccaataaa ggcgtgctca atctgcaaag caatatgccg
    17281 gacaccaaac cgggtctgta tgagccgact tcgccgccga ttatcaccga taaaaccatc
    17341 gtgatggccg gttcagtcac cgataacttc tcaacccgtg aaacatctgg cgtgatccgt
    17401 ggttttgatg tcaacaccgg ggagctgctg tgggcttttg atccgggcgc gaaagatccg
    17461 aatgcgatcc cgtctgacga acataccttt acctttaact caccaaactc gtgggcacca
    17521 gcggcctatg acgcgaagct ggatctggtc tatctgccga tgggcgtcac cacgccagat
    17581 atttggggtg gtaaccgcac accggaacag gaacgttatg ccagctcgat tctggcgctg
    17641 aatgccacta ccgggaaact ggcgtggagc taccagaccg ttcaccacga cctgtgggat
    17701 atggatcttc cggcacagcc gacgctggcg gacatcaccg ttaatggtca gaaagtgccg
    17761 attatttacg ctccggcgaa aaccggcaac atttttgtgc tcgatcgtcg taatggtgaa
    17821 ctggtggttc cggccccgga aaaaccggtt ccccaaggtg ctgccaaagg cgattacgtg
    17881 acccctactc aacccttctc ggaactgagc ttccgtccga cgaaagattt gagcggtgcg
    17941 gatatgtggg gtgccaccat gtttgaccag ttggtgtgcc gcgtgatgtt ccaccagatg
    18001 cgctatgaag gcatttttac gccgccatct gaacagggta cgctggtctt cccgggtaac
    18061 ctggggatgt tcgaatgggg cgggatttcc gttgatccga atcgtgaagt ggcgattgcc
    18121 aacccaatgg cactgccgtt tgtttcgaaa ctgatcccac gcggtccagg caacccgatg
    18181 gaacagccga aagatgccaa aggcacgggt acggaatccg gcatccagcc acagtacggt
    18241 gtaccgtatg gtgtcacgct caacccgttc ctctcaccgt ttggtctgcc atgtaaacag
    18301 ccagcatggg gctatatctc agcattggat ctgaaaacca atgaagtggt gtggaaaaaa
    18361 cgtattggta cgccgcagga cagtatgcca ttcccgatgc ctgtaccggt gccgttcaat
    18421 atgggtatgc cgatgcttgg cgggccaatc tccacggcgg gtaacgtgct gtttatcgcc
    18481 gctacggcag ataactacct gcgcgcttac aacatgagca acggtgaaaa actgtggcag
    18541 ggtcgtttac cagcgggtgg tcaggctacg ccaatgacct atgaagtgaa tggcaagcag
    18601 tatgtggtga tctccgcagg cggtcacggt tcatttggta cgaagatggg cgactatatt
    18661 gtggcttatg cgctgccgga tgatgtgaag taaccataat gcccggagag atccgggcat
    18721 atttccgaat acggtctttt tataccgtaa accctaacat catccccgta tcttcatgct
    18781 ccagcagatg gcagtgcgcc atataagcat gttctttcgg tgcatcgtga ttaaacttca
    18841 ccagcacttc gctgacatta ccttctacct taacggtatc tttccagcct gcgcgatgcg
    18901 tcgctggcgg tttgccattt tctgacaaga tacggaactg cgtaccgtgg atatggaacg
    18961 gatgcagcat catgtcgccc acgccagaga taacccaacg ttcgtactgc cctttcgccg
    19021 ccgcaaacat cggcttattc atatcaaacg cctgaccgtt gattttgttg gcatggtgga
    19081 aatcgaactt cccgctgtgg ttcatatgat tcatattgcc gtgccccata tggcccatca
    19141 tctggctgtg atccatcccg gccatggcct gatcgccata tttctccatc agcatctgca
    19201 tccccatcat atcgagcatt gggtccatag aaagttgcag attgcgtacc gtcagccctt
    19261 ccagcgaagg taacgcaggc aggctactta atgtgtctgg caaagcacca gaggcactaa
    19321 tggcaatcgg ctgaatccgc attaccggat gcggcttgtc aaacggcgca atcgccatcc
    19381 ccatctggct gaccggcagc gtcaccaggt caaagggttt gttatcgtta acctccacca
    19441 gcacttcaaa acgctcgccc atcagcactg gcagctcgtt caccttcacc ggttcaggta
    19501 gcagaccgcc gtcgctggca atcacataaa gcgggcgatt gtcgctggtg gcgaaattga
    19561 gcgagcgggc attacagcca ttgagcaaac gcaggcgcag ccagccacgc ggggcagcgt
    19621 gttgcgggta gattgcaccg ttggtcagca acgtatcgcc aaaccaaccc acagcggcgg
    19681 tcatcacatc cagttgataa tcaatctgcc cgtctgcgtt aaatttttta tcctgaacaa
    19741 tcaccgggac atcatcaata ccccactgtt ttggcagcat taatttcagg atctcgtcat
    19801 cttcaatcac caccaaacca gccagcccca tcgccacctg acgtccggtc ttgccatgtt
    19861 gatgtggatg gaaccagcag gtagcggcag gttgatcaac gttcaacgtc accgagcgct
    19921 tgccacctgg cggaataatt ccctgcgggc cgccgtccac ttcacccggt acttccagcc
    19981 cgtgccagtg caacgtcgtc tcttccgtca gttggttgta gatatcaacc gttaccgctt
    20041 tgccgcgctg taatttcacc gccggcccca gcagattgcc gttatagccc caggtagttg
    20101 cggttttccc gccaaaggtg gactgacctg cgccaatagt taactgaatg cgattacggg
    20161 catcggtcgt gagcaaatca gggattggta acgttgggcg ttccgccgca aatactgcgc
    20221 ggctccacag cggcaaggct gaagccaccc ccagcgcgac ggaatatttc aagaaatcac
    20281 gacgttgcat agttatttcc ttattcttaa gcaggcgaaa caaaatcaaa cgttgagcat
    20341 agtccttccc cttacgggaa ggtcaagccg cagacacaat ttaatcgaca ataatggtcg
    20401 tcgcctcgct cgcagtgtgc taacgtttat cttctttaag cccctggtag aagcaatgaa
    20461 gacgtttttc agaacagtgt tattcggcag cctgatggcc gtttgcgcaa acagttacgc
    20521 gctcagcgag tctgaagccg aagatatggc cgatttaacg gcagtttttg tttttctgaa
    20581 gaacgattgt ggttaccaga acttacctaa cgggcaaatt cgtcgcgcgc tggtcttttt
    20641 cgcccagcaa aaccagtggg atctcagtaa ttacgacacc ttcgacatga aagccctcgg
    20701 tgaagacagc taccgcgatc tcagtggcat tggcattccc gtcgctaaaa agtgcaaagc
    20761 cctggcccgc gattccttaa gcctgcttgc ctacgtcaaa taatccctga tacctttttg
    20821 tagaaatatt gaccgtgcat ccgcggtcaa tgttagctat tatgttgcgc cattttttta
    20881 cgggtgttaa caaaggaggt atcaacccat ggccgaaaaa aaacagtggc atgaaacgct
    20941 acacgaccag tttgggcagt actttgcggt agataacgtt ctgtatcatg aaaagaccga
    21001 tcaccaggat ctgatcattt ttgagaacgc cgcatttggt cgcgtaatgg cgctggatgg
    21061 cgtagtacaa accaccgagc gcgacgagtt tatctatcat gagatgatga cccatgttcc
    21121 gctactggcc cacggtcacg cgaaacatgt gctgattatc ggcggcggcg acggtgccat
    21181 gctgcgtgaa gtaacccgac ataaaaacgt tgagtcaatc acgatggtgg aaatcgatgc
    21241 gggtgtcgtg tcgttctgcc gtcagtatct tcccaaccat aacgccggta gttacgacga
    21301 tccgcgcttt aagctggtga tcgacgatgg cgtcaatttc gttaatcaaa ccagccagac
    21361 ctttgatgtc attatctccg actgcaccga tcctatcggt cccggcgaaa gtctgttcac
    21421 ttcggcattt tatgaaggct gcaaacgttg cctgaatcct ggcggtattt tcgttgcgca
    21481 gaacggcgtc tgctttttac agcaggaaga ggccatcgac agtcatcgca aactcagcca
    21541 ttacttcagc gatgttggct tttatcaggc ggcgatcccg acctattacg gcggcatcat
    21601 gacctttgca tgggcgacag ataacgacgc cttacgccat ctttcaaccg aaattattca
    21661 ggcgcgtttt ctcgcttctg gcctgaaatg ccgttattac aatccggcag tccatacggc
    21721 agcttttgcc ttaccccagt atctgcaaga tgcactggct tcacagccgt cctaaggaga
    21781 agataagaaa ttgaaaaaac tgaaactgca tggctttaat aatctgacca aaagtctgag
    21841 tttttgtatt tacgatatct gctacgccaa aactaccgaa gagcgcgacg gttatattgc
    21901 ttatatcgat gaactctata atgccaaccg tctgaccgaa atcctgtcag aaacctgttc
    21961 cattatcggg gccaatattc ttaacatcgc ccgccaggat tacgaaccac aaggtgccag
    22021 cgtcactatt ctggtgagtg aagaaccggt cgacccgaaa cttatcgaca aaacagaaca
    22081 ccccggccca ctgccagaaa cggtcgttgc ccatctcgat aaaagtcata tttgcgtaca
    22141 tacctacccg gaaagtcatc ctgaaggcgg tttatgtacc ttccgcgccg atattgaagt
    22201 ctctacctgc ggcgtgattt ctccgctgaa ggcgctgaat tacctgatcc accagcttga
    22261 gtccgatatt gtgactattg attatcgcgt gcgcggtttt actcgcgaca ttaacggtat
    22321 gaagcacttt atcgaccatg agattaattc gattcagaac tttatgtctg acgatatgaa
    22381 ggcgctgtat gacatggtgg atgtgaacgt ctatcaggag aatatcttcc ataccaagat
    22441 gttgcttaaa gagttcgacc ttaagcacta catgttccac accaaaccgg aagatttaac
    22501 cgacagcgag cgccaggaaa ttaccgctgc gctgtggaaa gaaatgcgcg agatttatta
    22561 cgggcgcaat atgcccgctg tttaacgtct caggcggagc acggaggctc cgcctgattt
    22621 acttacttct gctgcacgaa attacggtaa gccgccacca cctgaagaaa atcctcaacg
    22681 ccacacagtg acaagctctc ttcatcgtag tagttcatcc cctcttccat ttcatcgcca
    22741 gcgaattcca gttgattggc gcgaaccatc acctcttcac catccatcca tagcgtgtat
    22801 tcatgccctg cccgttgcca ggaacgttcg ctacctttca atgcgtgcgc cgcttgttcc
    22861 acttcatcaa gcaaggccag gttttctttc acctcttcat taaaccagtg cccgaccact
    22921 tcatgcccca tggacatgcg cacctttacc actccggtaa tatcgcgcag aaattcgtaa
    22981 tccatagtgt gttcctctgc tcccggcaat gcgccgaaat cgcattgcgc cattgatgta
    23041 attatcgcag tcttaccgga gaaaaacagc ggaacggcga tggtttagaa ataaaaaatg
    23101 cccgggaatc tcattcaccg ggcattgtgt cgtttatgcg cagcgcgtgc gcttacttat
    23161 taaaccgcag tctggaaaat caccccgtcc gctttttcgg tgtactgaga aagctggtcg
    23221 aagttcagat aacggtaagt atcaacggca gttttatcta cttgcgccac gtaggtctgg
    23281 tactcttccg gcgtcggcag tttgccaatc agcgccgcaa cagcagccag ttccgcagaa
    23341 gccaggaaga cattcgcgcc agtacccaaa cggttcggga agttacgggt agaggtggaa
    23401 accaccgtcg caccgtctgc tacacgcgcc tggttaccca tacacaggga acagccaggg
    23461 atctcgatac gagcaccact cttaccgaag acgctgtagt agccttcttc ggtcagctgc
    23521 gcagcgtcca tacgcgttgg cggtgccacc cacaggcggg tcggcaactg acctttgtgc
    23581 gcatccagca gtttaccagc agcacggaag tgaccgatgt tagtcatgca agaaccgata
    23641 aatacttcgt cgatcttctc gccctgtacc gcagacagcg gacgtgcgtc gtccgggtca
    23701 ttcggtgcac agaggattgg ctctttgata tccgccagat cgatgtcgat cactgccgcg
    23761 tattccgcat ctgcatcggc ttccagcagc tcaggattcg ccagccattt ttccatgccc
    23821 tgaatacgac gctccagggt acgacgatcg ccgtaacctt ccgcgatcat ccacttcagc
    23881 aggacgatgt tagagttcag gtattcaatg atcggttctt tgttcagctt gatggtacaa
    23941 ccggcagcag aacgctcggc agacgcatcg gtcagctcaa atgcctgctc aactttcaga
    24001 tccggcagac cttcaatttc cagaatacgg ccagagaaga tgtttttctt acctttcttc
    24061 tcaacggtca gcagaccttg tttgattgca tacagcggaa tggcgtgtac cagatcgcgc
    24121 agggtgatac ccggctgcat tttgcctttg aagcgtacca gaacggattc cggcatatcc
    24181 agcggcatta cgcctgttgc ggctgcaaat gccaccagac cagaacccgc cgggaaagag
    24241 ataccgatcg ggaaacgggt atgggagtca ccaccggtac cgacggtatc cggcagcagc
    24301 atacggttca gccaggagtg aatgacgccg tcccccggac gcagcgacac accgccacgg
    24361 ttcataatga agtccggcag cgtgtggtgc gtgttcacgt caactggctt cggatacgcc
    24421 gcggtgtggc agaaagactg catcaccagg tcagccgaga agcccaggca cgccaggtct
    24481 ttcagttcat cacgggtcat cgggccggtg gtgtcctggg aacctacaga agtcattttc
    24541 ggttcacagt acgcacccgg acgaatgcct ttcacgccac aggcacggcc taccattttc
    24601 tgcgccagcg agaagccgcg atcgctctca gcgacatctt tcgcctgacg gaacacatca
    24661 ctatgcggca ggccaagtgc ttcacgcgct ttggtggtca ggccacgccc gataatcagc
    24721 ggaatacggc cgccagcacg cacttcatca atcagcacgt cggttttcag ttcgaaggtt
    24781 gccagcagtt cgccggtttc gtggttacgc acttcacctt tgtacgggta aacgtcaatt
    24841 acgtcgccca tgttcaggtt agagacgtcg acttcgattg gcagtgcacc cgcgtcttcc
    24901 atcgtgttaa agaagattgg tgcaatttta ccgccgaggc acaaaccacc gccgcgtttg
    24961 ttcggcacat gtggaatatc atcgcccata aaccacagaa cggagttcgt ggcggattta
    25021 cgcgatgacc ccgtacccac aacgtcaccg acgtacgcca gcgggaaacc tttctgttgc
    25081 agagcttcaa tctgtttgat cgggccaaca acaccaggct gatctggctc aataccttca
    25141 cgggcgtttt tcagcatcgc cagcgcgtgc agtgggatat ccgggcgtga ccacgcatcc
    25201 ggtgccggag aaaggtcatc ggtgttggtt tcgccggtca ctttgaagac ggtaacggtc
    25261 agtttttcag ccagcgccgg gcgattcagg aaccattcgg catccgccca ggactgcatt
    25321 acctgcttcg catattcgtt acctgctttg gctttctctt ctacgtcata gaagttatcg
    25381 aacatcagca gtgtgtgaga aagtgctttg gcagcgatcg gtgccagttt ggcatcatcc
    25441 agcgcgtcga tcagcggatg aatgttgtaa ccaccctgca tagtgcccag cagttcaatg
    25501 gctttttccg gagtcagcag tggggatttg gcttcacctt tggcgacagc agccaggaag
    25561 cctgctttga cataggcggc ttcatcgacg ccagggggaa cacggttggt taacagatct
    25621 aacaggaatt cttcttcgcc cgcgggcggg tttttcagca gctctacaag cgcggccatt
    25681 tggtttgcat ccaggggttt gggcgcaatc ccctcagcgg cacgctcagc tacgtgctta
    25741 cggtattctt ctagcacgac ggttctcctc gctctcattg tcatagtgcg gcaggcgatt
    25801 ctcttcacgc tcctgtgaga cagcagtttg tagggtaaat gcccagtacc gcaacgggca
    25861 gaatagcagg attttgacga tgtgttaatc tgtttacaaa aaagcaacat aaaaaagtgg
    25921 ctgaatcgtt aaggatggtc tagagattat ttccctccgt aaaaacttcg ttaattcgca
    25981 tggtgataat cacctttctc aacgaatccc aagattagtc aaaatttaaa ctacggcctc
    26041 tttatactcg gattcacagc acctgcgggt ggcagttcgc cgaccattgc gatttccttg
    26101 agatccgaat tatgaaaatg actttgccgt ttaaacccca tgtgctggcg ctaatttgca
    26161 gtgccgggct ctgtgccgcc tctgccgggc tatatataaa aagccgcaca gtggaagcgc
    26221 ctgtggaagc gcaatcgaca caacagactg cgcctgacat ctccgcagtt acgcttccag
    26281 caacggtttc cgtgcctcct gtaacacctg ccgtcgtcaa atccgcattc agcactgctc
    26341 aaatagatca atgggttgca cctgtcgcgc tataccccga ctctctgctt tcacaagtgt
    26401 taatggcatc aacctatccg gcaaacgttg ctcaagcagt gcaatggtcg cacgataatc
    26461 cacttaaaca aggcgatgct gctattcagg cggtatctga ccagccctgg gacgccagcg
    26521 tcaaatcact ggtggccttt ccacagttga tggcattgat gggcgaaaac ccgcaatggg
    26581 tgcaaaacct gggcgatgct tttctggcgc agccgcagga cgtgatggac tcggtacagc
    26641 gattgcggca actggcgcaa caaaccggct cgctgaagtc atcaactgaa caaaatatca
    26701 tcacgacaac gaaaaaagtc gtaccggtaa atcagcccgc caacgcccct gccacacaat
    26761 caaataccgt ttctacgtcc agccccgtcg tcgcagaacc tgcaccgacc gtaataacca
    26821 ttgagccagc caatccggat gtggtttata ttccgaacta caacccaaac gtggtttacg
    26881 gcagttgggc caataccgct tatccaccag tttatctgcc gccgccagcc ggagaaccgt
    26941 ttgttgacag ctttgtgcgc ggattcggct atagcatggg cgttgctacc acatacgcac
    27001 tattcagcag catcgactgg gacgacgacg atcatgacca tgaccatcat catcatgacg
    27061 atgatgatta tcatcaccac gatggcggtc atcgtgacgg taatgactgg caacacaacg
    27121 gcgacaacat caatatcgac gtcaacaatt tcaaccgtat caccggtgag catcttactg
    27181 ataagaatat ggcatggcgg cacaatccaa actaccgtaa tggtgtgacc tatcatgatc
    27241 aggatatggc aaagcggttt catcaaaccg atgtcaacgg cggaatgagc gccacgcagt
    27301 tacctgctct atcgcgcgac agccagcgtc aggcggcagc aagtcagttt cagcaacgaa
    27361 cacacgccgc ccccgtcatt acgcgagata cccaacgtca ggcagcggca cagcggttta
    27421 atgaagcgga acactatggc aattatgacg acttccgcga gttcagccgc caccaaccac
    27481 tgacccagca gcaaaaggac gccgctcgcc agcgttatca gtctgcctca cctgagcagc
    27541 gccaggcggc ccgtgagaaa atgcagacta gcccgcagaa tcaacagcaa agagatgcag
    27601 cacgtcagcg tattcagtcc gcgtcgcctg agcagcgcca ggtgtttaag gaaaaagtac
    27661 agcagcgccc actgaaccaa gagcaacgtg ataacgcccg ccagcgtgtt caatcggcat
    27721 cacctgaaca acgtccgttt tttcgggaga aagttcagga gagccgcccg caacgtctaa
    27781 acgacagtaa ccgtactgcc aggctgaata acgagcagcg gtcagcagta cgcgaacgtc
    27841 tctctgaacg tggggcaaga agactggaaa ggtaaattgc agacgtaaaa aaagcggcgt
    27901 ggttagccgc ttttttaatt gccggatgtt ccggcaaacg aaaaattact tcttcttcgc
    27961 tttcgggttc ggcaggtcgg taatgctacc ttcgaacact tctgccgcca ggcccacaga
    28021 ctcgtgcaga gtcgggtgcg catggatggt cagtgcgatg tcttcagcgt cacaacccat
    28081 ttcgattgcc aagccgattt cacccagcaa ctcgccgccg ttagtgccga caatcgcacc
    28141 accgatcaca cggtgagatt ctttgtcgaa aatcagcttg gtcataccgt ctgcgcagtc
    28201 ggaagcgata gcacgaccag aagcagccca cgggaaggtg gcggtttcgt agctgatgcc
    28261 tttctctttc gcttctttct cagtcagacc tacccatgca acttctggtt cggtataggc
    28321 gatggacggg ataactttcg gatcgaagta atgtttttta ccggcgataa cttcagcggc
    28381 aacgtgacct tcgtgaacac ctttgtgtgc cagcattggc tgaccgacga tatcgccgat
    28441 agcaaagatg tgcggtacgt tggtacgcag ctgtttgtca acgcggatga aaccacggtc
    28501 gtcaacttcc acgccagctt tgcctgcgtc gaggttttta ccgttcggca cacgaccaat
    28561 cgctaccagc acggcgtcgt aacgctgcgg ttcagcgggt gcttttttgc cttccatcgt
    28621 cacataaatg ccgtcttctt tcgcttcaac ggcggtaact ttggtttcca gcatcaggtt
    28681 gaatttcttg ctgatacgct tggtaaagac tttaacgatg tctttatcag ctgccgggat
    28741 gacctggtcg aacatttcaa ccacgtcaat ctgtgaaccc agcgcgtggt atacggtgcc
    28801 catttccaga ccgatgatac cgccacccat taccagcagg cgttctggta cttctttcag
    28861 ttccagcgcg tcagtggagt cccagatacg cggatcttca tgcggaataa acggcagttg
    28921 aatcgggcga gaacccgctg caatgatcgc gttgtcgaag ttgatcacgg ttttaccgtt
    28981 ctcaccttca acttccaggg tgttagcccc ggtgaattta cccagaccgt tgaccacttt
    29041 gactttgcgg cctttcgcca taccagccag accaccggtc agctgattga tcactttctc
    29101 tttccaggta cgaatcttgt cgatatcggt tttcggttcg ccgaagacga taccgtgttc
    29161 agccagcgct ttggcttctt cgataacttt tgctacgtgc agcagtgctt tagaagggat
    29221 acagccgacg ttcaggcaaa caccgccaag ggtgttgtaa cgttctacga ttacggtttc
    29281 cagacctaaa tcagcgcaac ggaaggcagc ggagtaacct gcggggcctg ccccaagtac
    29341 cacgacctga gttttgattt cagtactcat catgacctct atatatttat ctccggcggg
    29401 tctgacgttt tttttatgac gcccattatc caccgggtcg ttctatccgt cggtatttta
    29461 caaaattgtt aacaattttt aaacaacaaa cggcaaccga tttgtctatt cgctaataac
    29521 ctcaatacat tcatgagatt accagaaaaa agccggccgt tgggccggct cttttactta
    29581 catcaccaga cggcgaatgt cagacagcgt gttgttaatg atggtaatga aacgggcacc
    29641 atcagcaccg tcgatcacgc ggtggtcgaa ggagagagaa atcggcagca tcagacgcgg
    29701 cacgaactct ttaccattcc acaccggctc catcgcggac ttggaaacgc cgaggatagc
    29761 cacttccggc gcattcacaa tcggcgcgaa gtgggtagta cccaggccgc cgatgctcga
    29821 gatggtgaag caaccgccct gcatttcgcc cgcagtcagc ttaccgtcac gcgctttctt
    29881 agaaatagtc atcagctcgc gagacagctc gatgatgcct ttcttgttga cgtctttgaa
    29941 taccgggaca accagaccgt tcggggtatc caccgccaca ccgatgttga tgtatttctt
    30001 cagggtcaga cgctgaccgt cttccgacag cgaactgttg aagcgaggca tctgctcaag
    30061 agctgcagca acggctttca tgatgaagac aaccggggtg atcttcacat ccagcttacg
    30121 tttcgctgct tcttcgttct gctgtttacg gaacgcttcc agctcagtga tatcggtttt
    30181 gtcgaagtga gtaacgtgcg ggatcatcac ccagttacgg ctcaggttag caccagagat
    30241 tttctgaatg cggcccagtt ccacttcttc gatttcacca aacttgctga agtccacttt
    30301 aggccacggc agcatgcctg ggataccgcc gccagttgcc gccggagctg cttctgcacg
    30361 tttgattgct tctttcacgt aagcctgaac gtcttcgcgc aggatacgac ctttacggcc
    30421 agtgcccttc actttcgcca ggttaacgcc aaactcgcgt gccagacggc ggatcagcgg
    30481 agtcgcgtga acgtaagcgt cgttttcagc aaattcagat ttgccttcgg ctttcgcagc
    30541 cggtgctgct gccggggctt cagcttttgc tgccggagcc ggcgctgccg cttcctgttt
    30601 cgcaggagct gccgcaggcg ctgcgccttc aacttcgaag atcataatca gcgaaccagt
    30661 tttcacttta tcgccaacgt tgactttcag ttccttcacg acgcctgcaa acggagccgg
    30721 aacttccata gaagctttat cgccttctac ggtgatcagt gactgttcag cggcaacttt
    30781 gtcgcccact ttcaccatca cttcggtcac ttcaacttcg tcaccgccga tatccggaac
    30841 gttaacttct ttcacgccag ctgctggtgc agaggccgct gccggagccg cttcctgttt
    30901 agccgccgga gctgccgcgc cagcttcacc cgcgacttcg aagaccataa tcagcgagcc
    30961 ggtagacact ttgtcaccca cgttcacttt gatctctttc acggtacctg caaacggagc
    31021 cggaacttcc atagaagcct tgtcgccttc tacggtgatc agcgactgtt cagcttcaac
    31081 tttgtcgccc actttgacca ggatttcggt cacttcaact tcgtcgctgc cgatatccgg
    31141 aacgttaacg tcttttgccg ctgcagccgc tggtgctgct gccggagcgg cttctttctt
    31201 ctcttctgcc tgagcaggtg cagcgtctgc tgcaccgtcg gcggaatcga aaatcataat
    31261 cagtgcgccg gtctgggttt tatcgccaac agagactttg atctctttaa cgatacccgc
    31321 ctgcggagat ggtacttcca tagaggcttt gtcgccttct acggtgatca gcgactgttc
    31381 ggcttcaact ttgtcgccca ctttgaccag gatctcggtg atttcaactt catcagcccc
    31441 gatgtccggt actttgattt cgatagccat tattctttta cctcttacgc cagacgcggg
    31501 ttaactttat ctgcatcgat gttgaatttg gcgattgcgt cagcaaccac tttcttatcg
    31561 atttcgccac gtttagccag ttcgcccagc gccgcaacca cgacataaga agcatcaact
    31621 tcaaagtggt gacgcaggtt ctcacggctg tcggaacgac cgaagccatc agtacccagt
    31681 acgcggtagt cgtcagccgg tacgtaagta cggacctgct cagcgaacag tttcatatag
    31741 tcggtagatg ccactgccgg agcgtcgttc atcacctgag cgatatacgg aacgcgcgga
    31801 gtttccagcg ggtgcagcat gttccagcgt tcacaatcct gaccatcacg cgccagttcg
    31861 gtgaaggaag tcacgctata aacgtcagaa cctacgccgt aatctttcgc caggatctct
    31921 gccgcttcac ggacgtgacg caggatagaa ccggagccca gcagctgaac tttacctttg
    31981 ctaccttcaa tggtttcgag tttgtagata cctttacgga taccttcctc agcaccttcc
    32041 ggcattgccg gcatgtggta gttttcgttc agcgtagtga tgtagtagta aacgttctct
    32101 tgtttttcac cgtacatacg ctccagaccg tcatgcatga tgacagcaac ttcgtaagcg
    32161 taagccgggt cgtaagagat acagttcggg atagtcagcg actgaatatg gctgtgacca
    32221 tcttcgtgct gcagaccttc accgttcagg gtggtacgac cggaagtacc gccgatcagg
    32281 aagccacgcg cttgctggtc gccagccgcc cagcacagat cgccgatacg ctggaaaccg
    32341 aacatcgagt aatagatgta gaacgggatc atcggcagat tgttggtgct gtaagaggtc
    32401 gccgctgcca gccaggaaca acctgcgccc agctcgttga tcccttcctg cagaatctga
    32461 cctttctcgt cttctttata gtaagcaacc tgctcgcggt cctgcggggt gtactgctga
    32521 ccgttcgggc tgtaaatacc aatctgacgg aacagacctt ccataccgaa ggtacgcgct
    32581 tcgtcggcga tgatcggtac cagacgatct ttgatcgact tgttcttcag catcacgttc
    32641 agagcacgaa cgaaagcgat agtggtagag atctctttgc tctgctcttc cagcagcgcg
    32701 ccgaaatctt gcaggctcgg cagctccagc ttctcggtga agttcggctg gcggcttggc
    32761 agataaccgt gcagtttctg acgttgagcg tgcagatagg tatgctcttc agaaccttcc
    32821 gggaaggtga tgtacggcag tttttcgata tctgcatcag acaccggcac attgaaacgg
    32881 tcgcggatgt gacgcacgcc gtccatgttc attttcttaa cctggtgcgc gatgttttta
    32941 ccttcagccg cgtcgcccat gccgtaacct ttaatggtat gagcaaggat taccgtcgct
    33001 ttgcctttgg tttcctgcgc tttcttgaat gcagcgtaga ttttcttcgg atcgtgacca
    33061 ccacggttca gtgcccagat ctgctcgtca gtccagtctg caaccagtgc tgcggtttca
    33121 ggatatttac cgaagaagtg ttcgcgaaca tacgcaccat ctttcgattt gaaggtctgg
    33181 taatcgccgt caacggtttc gttcatcagc tggatcagtt taccgctggt atctttacgc
    33241 agcagttcgt cccaacggct accccacatc actttgatca cgttccagcc agcaccttcg
    33301 aagatgcctt ccagttcgtt gatgatcttg ccgttaccgg tgaccgggcc gtcaagacgc
    33361 tgcaggttac agttgataac gaagaccaga ttatccagtt tttcacgggt agcgatggtg
    33421 atcgcacctt tggattccgg ttcgtccatt tcaccgtcgc cgaggaacgc gtaaacggtt
    33481 tgtttagagg tatctttcag gccacggtgt tccagatatt tcaggaattt agcctggtaa
    33541 atagcaccaa tcggacccag ccccatagat acggtcggga actgccagaa ttccggcatc
    33601 agtttcgggt gcggatagga agagaggcca ttgccgtgaa cttcctgacg gaagttatcc
    33661 agctgctcct gagtcagacg accttccagg aaagcacgag cgtaaacgcc tggggagatg
    33721 tggccctgga agtaaaccag gtcgccgcca tcctgctcgt tgcgtgcacg gaagaagtgg
    33781 ttaaagcaca catcataaat ggttgcggaa gactggaagg acgccatgtg gccgcccagt
    33841 tcgaggtctt ttttcgacgc acgcagcacc gtcatgatgg cgttccagcg gatagctgaa
    33901 cgaatacggc gttccagttc cagattaccc ggatactccg gttgttcttc aacggggatg
    33961 gtgttgatgt agttgctgat accggtgcct gcagctacgt tgactccgcc tttgcgggct
    34021 tcagcaagca gttggtcgat cagatactga gcacgctcaa caccttcttc acggatgacc
    34081 gattcgatcg cctggagcca gtcgcgagtt tcgatcggat ccacgtcatt tgggaaacgt
    34141 tctgacatgg gttattcctt atctatctaa taacgttgag ttttctggaa cctgtcccat
    34201 tgaactctcg ccggaaagct caataagaca ggttctacgt ttagttgccg cgcttttata
    34261 tgcgcttgat ttacaacatc ttctggataa tttttaccag aaaaatcact aattctttcg
    34321 ttgctccaga cgacgcagag aacgctcacg gcggctctct tcacggcttc tgtcgagcaa
    34381 aatttcttcg ataaaggcca gatggcgatg cgatgcttcg cgcgcttctt ccggcttacc
    34441 ggccataatc gcttcaaata tgcgggtgcg gtgactactc accagcggca gcatctcgcg
    34501 acgcgaatag agcaattcga agttctggcg gacattctga gccaacatcg gctccataca
    34561 ccttagcaga tgaagcagaa ccacattgtg ggccgcttcg gtgacggcaa tctgatactg
    34621 gagtacggca tttgattccg cgtccagatc gccagactgc tgcgccagct ctatggcatg
    34681 gtggagttca cggatgcgtt ccttgtcttc atcggtacta cgcagcgcgg cgtaataagc
    34741 ggcgatacct tccagggcgt gtcgtgtttc gagcaagtca tactgtgatt caggatggtc
    34801 ggagagcagc tccaccagcg gatcgctgaa gctttgccag aggctgctct ggacaaaagt
    34861 gccgccaccc tggcgacgaa gcaacaagcc cttcgcttcg aggcgttgaa tcgcctcacg
    34921 caaagaggga cgggagacgt cgaactgttt tgccagttcg cgttccggtg ggagtttttc
    34981 gcccgggcgg agagtgcctt cgaggatcaa aaactccagt tgctgctcaa tcacatcgga
    35041 gagttttggt tggcggattt tgctgtaggc catgagttcc tgtcttaagc cacttgccga
    35101 agtcaattgg tcttaccaat ttcatgtctg tgacgctaaa gtaacaaagt attcacctta
    35161 tgtccataca ggttttgatt gaaatcatga aactgtgcac attttaacaa cttgacatat
    35221 ataacgtttc aaagttgtaa ctatgcacaa atgttaaatt tacccatcaa ggggtgacct
    35281 taacagaatt gaaacgaaaa aatatttcct ctgaaccgat tcaccaagca acaaaacgca
    35341 taacaattca attatgtgaa ttaatatgta aaatgaatgt tcagggaagg agagaaaggt
    35401 agtatttacc tatgttttct ttttacattg cttattatca ctgcaatcgc caccataacc
    35461 ttctcgtagc gaaaatcatc acttaaccag aacgtgatga ttttcaggtg acagattctg
    35521 tttagagttc attctgaatc tttgaacaaa ggcaatcctt gcgaacgccg ccattctttg
    35581 acgattttca ggatgttttc aggttcatca tctcccttct ttgcaggata gtagataaga
    35641 tcgctcatca acggatgttg tgtaattctg gtaagatgtt cttctagatc atcccaatat
    35701 ttgtcaagct cttccccttt taattgagcg ttatccccgg ttggatttgt aaactcgcca
    35761 agcaactcaa tgaattcccg ctctgtgtaa tcttctattt tatctttaaa attatacatt
    35821 taactatctc ctgtaataaa tttcatcatg caaatgaggt gtgccctcct taaattatca
    35881 atatcgtaaa ttccgccact atattcaatc gcaacacgat gatacatgtg gaatttttta
    35941 acgatttctt tagtgccata atgccaacct tcaagtggtg cttttgcgat taa
//
LOCUS       DAPOXO010000050        34857 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPOXO010000050 DAPOXO010000000
VERSION     DAPOXO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34857
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.050"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1036
                     /locus_tag="ROH59_002870"
     CDS             <1..1036
                     /locus_tag="ROH59_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805329.1"
                     /translation="SEIQSRYSLLEERYHSDLKRLDFISEGSHYFTSLQEVPCSLCGQ
                     NLLHPHSENAKKLMNSNEVRRSSLAEAAKIHGYLAGLQKAMSDLDRRKEALNIDRYKS
                     KESLDGMKNQIKYTFEPLLTLSKESLDLAIEQRAERDSELNDRQRWFELLKHQKDIEI
                     LLEKSSQPRLEWEGLSTRTLAELCREIETVLKDWKWGAEPDVSFNEKEYDIIVDGQPR
                     QSHGKGVRAILYSAFIIGLLKYCIKKGYPHPGLVVIDSPLTSYKKKAAATVSGFDEPI
                     SAGIEEGFWHSLTQLPDTLQIIVIENKEPPVSIMNKVHYEWFAGEHAMDGERRALIPL
                     PSKNSAILMK"
     gene            complement(1916..2251)
                     /locus_tag="ROH59_002871"
     CDS             complement(1916..2251)
                     /locus_tag="ROH59_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805330.1"
                     /translation="MKRAILLVLIAAGLLAGCGEKTPKCSSDDAKNLVGDIARKTIEK
                     GMKLDKDVRISVENVRTISHESDLDVYQCAADLTFTKPDLQNSLPITYRIQKTDEGKG
                     PFYINVTGL"
     gene            complement(2282..2641)
                     /locus_tag="ROH59_002872"
     CDS             complement(2282..2641)
                     /locus_tag="ROH59_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDX4805331.1"
                     /translation="MNRKLLALFMAAITLPVAAAQYVKPGAVLTLHPGQNNAEFNINA
                     STGDGSGVCNMEGTAQQIAAGESQKRRWVWNDNASECVAVISELTNGKASIMTRGCEG
                     YCGASAAGAMDGLFNKK"
     gene            complement(2656..3183)
                     /locus_tag="ROH59_002873"
     CDS             complement(2656..3183)
                     /locus_tag="ROH59_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805332.1"
                     /translation="MATTITEITECFEYFFSSLYRREFVKTLRLNECSERELLPLVRC
                     YLLGWFADNVSPEVKSKLPGTVSGHGYIDFVIDDVAVEFAVRKPTAARSNVSATVNST
                     EVKKLMKHDGKALLVLFDFSDTPYSEEQIESFRNWPSLGRGNHRKSAFNVVYFFVEKR
                     RPLALGKITKNIRIT"
     gene            complement(3195..3464)
                     /locus_tag="ROH59_002874"
     CDS             complement(3195..3464)
                     /locus_tag="ROH59_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4805333.1"
                     /translation="MRNSTASQKKQIKGSSGNWHRADIVAALHKRGLTLALLSRSHGL
                     APRTLNNALERHYPRAERIIAGALDTTPETLWPERYALKNGPNSR"
     gene            3586..4074
                     /locus_tag="ROH59_002875"
     CDS             3586..4074
                     /locus_tag="ROH59_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001543672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805334.1"
                     /translation="MSSKRTVSAIPTHPEASVEEAKDWLTAEEFTHIEGMPGTARGAR
                     MRLEKLASLHPEIRRKRTAGKGVVYHISAATMSLDDERNRAKGEAFTLNDSDRQLSLW
                     VQLYRNMSPASRAQLMEQALRLVKDDLMSQGPNVSELAVQIMKLPEDERKRLFEKLNG
                     KV"
     gene            4429..4821
                     /locus_tag="ROH59_002876"
     CDS             4429..4821
                     /locus_tag="ROH59_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2787 family protein"
                     /protein_id="HDX4805335.1"
                     /translation="MPVDQELINIILNEAGNPPPHKAKITAVSLLFKDLSYSAEKGGY
                     HPVEIRIISRNDEWYFDYITDFSYMGTVYPELEKEIDISWSQQYVFLAYVGDLPVNAG
                     RELFELWQSNFIQYHGMNIYTITVLWES"
     gene            4941..5402
                     /locus_tag="ROH59_002877"
     CDS             4941..5402
                     /locus_tag="ROH59_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805336.1"
                     /translation="MLSWLYDGRVKRRPLMNWLIQTYQQRWPLHEWLTEGIEEDRLDW
                     LIAQVLQKGHYRRQFPVEITRPFAGKRGLTDGRLFREMQRFLDVTDHSRLIMLSDQFH
                     WSLLVKMDEEMLCFFDSNGRTTMPRKAFSLRTGVTRRQLFPDAIYFIEREF"
     gene            5404..5856
                     /gene="radC"
                     /locus_tag="ROH59_002878"
     CDS             5404..5856
                     /gene="radC"
                     /locus_tag="ROH59_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDX4805337.1"
                     /translation="MTMFTQRETRILDQARDIISRYYQRGVQLCSPDDVRRCVMVELA
                     PLEHEEFGIILLDNHNQLLHREILFRGTLNSVSVHPREVIKRVLKHNAAAVILVHNHP
                     SGEPEPSRCDIQLTKKLQELLEILDVRLLDHFIVAGTETVSMAERGLV"
     gene            5903..6832
                     /locus_tag="ROH59_002879"
     CDS             5903..6832
                     /locus_tag="ROH59_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019083242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDX4805338.1"
                     /translation="MSRTALRQVVPVVQTTVFDAYIVGLAPSGRRGITSLLNRSASIL
                     KHGADAADYPWEQLNYAAVAKVRAALLDDGYAVSSVNMALSALRGVAQTAFNLNYMDA
                     ETLARIRSVKRVSGDVQRKGRALGRQEIRVLIQAAKQHPQSVRRCRDVAIVLMLCGTG
                     LRAGELVKLERRDYDNGILTVRQGKGRKYREIHVADAVDKAIRAWLKVGADEADSALF
                     RRIQRSGKVASQPLTTTGLTGILAELQQTAGIARFTPHDMRRTFITRLLEQGVDINTV
                     RQLAGHSDISTTTRYDCRGDTMKISASKRIRCF"
     gene            complement(6819..7433)
                     /locus_tag="ROH59_002880"
     CDS             complement(6819..7433)
                     /locus_tag="ROH59_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805339.1"
                     /translation="MIGNQSNKADARCHRERKSSNEVFEFLEKKLYLGRDTRQKLALI
                     ARKLTGAGFSPDKFAAEKAADVLSACVNHMFNDLLNEGEPNGIYRPEEHPMIVPARSP
                     KALEIYTVYQLVKGRFDKLHTGESDREKYASVAEKLNEYGIWKPRLKRLSDGKEWARE
                     DVAWMLQPENINAQINIQNQKYARLSAEDETETESGNASTAKNI"
     gene            7656..7853
                     /locus_tag="ROH59_002881"
     CDS             7656..7853
                     /locus_tag="ROH59_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HDX4805340.1"
                     /translation="MNTNRILRKKEVLHLTGNSSATLYRLISKGFFPLSKRLTGDNGR
                     AVGWLESDINNWVNSRMQAGE"
     gene            7855..8322
                     /locus_tag="ROH59_002882"
     CDS             7855..8322
                     /locus_tag="ROH59_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805341.1"
                     /translation="MKEIKSKTSSAKKTLVPWFETMGKQVGLSQETISAVLKEQRLRI
                     RKLNYASAYTVSNILIQDCGGADDMWSNYAKLALILERCKYIPCGSRACAYCSTAQQL
                     HYQGVDVTGEYALYQLPELFLDFLETNDKNSSYHWDYNKLVERHEDAQARSFG"
     gene            8410..9264
                     /locus_tag="ROH59_002883"
     CDS             8410..9264
                     /locus_tag="ROH59_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805342.1"
                     /translation="MNDSYYFRTSDPDYIRHAPSMLEILSKAFPTIITQQESEYELQR
                     LNHLLNKLKGSNRCYNIIAQKLRQCRNGSPCNSLICPHCQRERILAQLAMLHVLPGNS
                     AEYVGVVLFFNKDTQTPPPWKNIGALRAQIGRYKQRISRVLNRLGYAGPATGTFSMMR
                     HMPDGPEERIFWVPQLCLFLPNDSTLIKGLKAHMSRSGGAFIDASTLNTPVIVLRYKD
                     PARLISCALNPVWHTADYTLTDKDALVKSRMELLKGRTLLKSLLTLDSLGTGVVSFSF
                     GQPPGKVH"
     gene            9865..11238
                     /locus_tag="ROH59_002884"
     CDS             9865..11238
                     /locus_tag="ROH59_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805343.1"
                     /translation="MKIPKWVYDRITEITDYVVGDTQWAVTRRQTVRWFLAHIWLETD
                     DDGWTICTVRDIRSSYASLLGQCEISYQGECFMSTLTDFLPTLSDIEFRAGKASKDPE
                     KRRASAWRFNPLLPVCDESARGKLNLVDLDTGESVSFRALLQGNGKAPGHAIDVEKRQ
                     TALKQTEKDFLAKVGRGRMSIQFVKELRSREPDHYYRAGIRSLNHLYNGRIEGQYVTY
                     DHHYRLTFGGRYYDQAFQNLPNEFKAKFRTGLLNYDIEACNLACLNHLFRQYDVDYRV
                     KSSIYKTMMEHTGLTRKQCKQMVHTTTYRIGRVTIGVNDGLGAKVYGWCGNSKKKALK
                     ILRWWNRYISPLKSALESLLERVHGAHRKSCSSPRNYHRYANEVGLILDLNSEVYQRE
                     KTHHHQYARNKALLAFMICGVEQAYIREVVSMNPGRVCMLDHDGVVATGALSLPDWRG
                     FTMKVKD"
     gene            11416..12040
                     /locus_tag="ROH59_002885"
                     /pseudo
     CDS             11416..12040
                     /locus_tag="ROH59_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830285.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            12235..14892
                     /locus_tag="ROH59_002886"
     CDS             12235..14892
                     /locus_tag="ROH59_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2339 domain-containing protein"
                     /protein_id="HDX4805344.1"
                     /translation="MDELLTLGCIALFFALVVVPILAIIALSRSTAVRSELATLRRRV
                     EVLEQRGVTEAPATVVTTVPQSVSQMVVPVETSSPAVNIVLSEPVADVTPESVDPWRP
                     QPKPQNEALPTPAVEQSSAFGGVMSSLVRWFMQGNPLAKLGILLLFLGFSFLLRYTVE
                     HSLFPLELRLVATSLFAIALLVVGWRLRHKQLVYALIIQGGATGTLYLTVFGAFWLWQ
                     MLPMTLAFALLVAICAASVGLAIMQKALSLAMLASIGGYLAPLLLSTGGGSHVALFSF
                     YLLLSVGILAISIWQHWRELNLLGLLFTFGIGGLWGLDGYRSEYYLSSQLFLIANTII
                     FGVLSVALSLRAQEKGKQIIDGVLLFASPLVGFGMQYAITRHMEYGPALSALGYGGFY
                     LALAWLALRRYPSLGRPLVLAALALGGAFTTLAIPLALSARWTAMAWALEGLGILWLG
                     VQQQQRRMSYSGTALLVLAVCSALWAQMNGMSALSLVLIFAVLSLSWLAAAWLWRNIQ
                     LQGSWVLLAGGLIFWIIALIGASQLVLKKDSLVLSGVLALMAISVWGWRIVSGRLAWW
                     ELDVSKWLLWPTMLVMLLSQISQHEIFAAGWQNLAWCLALPAAGALLWRDAETLPPRL
                     SRLAHLSLFWMILLALAAELFWFAQDLPWGMAAWGSGLMMAAGGLLIFLVHEAVHRQL
                     WPFRSWPALYASQAMIPVAAVLVVLLVLTNLQDGVVYRQTWLPLVNPLEEGAAFALLG
                     LIVFYRVSQRFFPVQISVCRPWPLIALLALSFWWLNGILLRALAWYGEVPWSAETLWH
                     SRLIQTCFALFWMLAALVVMLRATRRCSRREWLCGSVLLGIVIVKLMLVDSARGGGLA
                     RAVTFIGVAILVLIVGYFSPLPPKAGEEK"
     gene            14889..16284
                     /locus_tag="ROH59_002887"
                     /pseudo
     CDS             14889..16284
                     /locus_tag="ROH59_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383163.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3999 domain-containing protein"
     gene            complement(16471..16608)
                     /locus_tag="ROH59_002888"
     CDS             complement(16471..16608)
                     /locus_tag="ROH59_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805345.1"
                     /translation="MGQHGKSLPSFDAPETLKGRKIEWEYENLTHGNKAYNGYVTAIL
                     N"
     gene            16767..16964
                     /locus_tag="ROH59_002889"
     CDS             16767..16964
                     /locus_tag="ROH59_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805346.1"
                     /translation="MSNPGPLAALVYGFILIVLLSVSLILYSIGRTIKNEIGKGIAYA
                     LTGILLILSLLVGAFILTLLT"
     gene            17061..17417
                     /locus_tag="ROH59_002890"
                     /pseudo
     CDS             17061..17417
                     /locus_tag="ROH59_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(18040..18894)
                     /locus_tag="ROH59_002891"
     CDS             complement(18040..18894)
                     /locus_tag="ROH59_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011871062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX4805347.1"
                     /translation="MKYRFINDHREIWSIVTMCRVLKVARAGFYVWLHRPVSAGEKDN
                     QRLLELIRDAYALSGGVYGYRRVHGDLREIGEVCSRNRVARIMKRNRIQAVHGYKVPR
                     GVRGRPSLIAPNRVQREFTMVKPNQVWVTDITYIRTWQGWLYLAVVIDLFARNVVGWS
                     MKPTLSRELALDALLMAVWRRKPAENVIVHSDQGSQYGSDDWQRFCRANNLAPSMSRR
                     GNCWDNAVAESFFSSLKKERIRKRIYKTRDMARADIFDYIEVFYNRTRRHSHLGGVSP
                     EAFEKASP"
     gene            complement(18891..19175)
                     /locus_tag="ROH59_002892"
     CDS             complement(18891..19175)
                     /locus_tag="ROH59_002892"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX4805348.1"
                     /translation="MGTPRFTPEFKEEAVRQVTERGYSVADVSERLGVSAHSLYKWVR
                     SVRPDNSGHQAQDLLDARTEILRLKAQLKRTEEERDILKKAARYFAREPD"
     gene            complement(19286..20461)
                     /locus_tag="ROH59_002893"
     CDS             complement(19286..20461)
                     /locus_tag="ROH59_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDX4805349.1"
                     /translation="MLTDTQCRTAKPKEKLYRLNDFNGLYLEVKPNGKKAWRYRFKLN
                     GKSSMFALGEYPTVKLAEAREKCEQARKQVADGVSPTQARQLDKIRKVNDASNTFELI
                     AKEWLQMKDWAGITKTRRLDMLERVVFPAIGKLPVREITPHHILKILQETAKRGAPTV
                     AAEARRTISSVFELAVATLRADSDPVWPVRKALPANKTQHKQALNPQQIGKLLSCFDN
                     SRGSYQVNYCMWLMWWTLARPAEATEAEWTEFNLDNALWTIPAARMKARREHVIPLPF
                     QAVKMLRTLQGLTGHRQHLFPGRDNPLGPMTSHSLRQLLKSLGWSGTYSPHATRTTGS
                     TRLNELGYRPDAIEAQLAHADTNNVRRTYNHATYLDERKVMMQEWADMLDKWVAGFK"
     gene            complement(20676..21767)
                     /gene="ychF"
                     /locus_tag="ROH59_002894"
     CDS             complement(20676..21767)
                     /gene="ychF"
                     /locus_tag="ROH59_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDX4805350.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAVRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            complement(21884..22468)
                     /gene="pth"
                     /locus_tag="ROH59_002895"
     CDS             complement(21884..22468)
                     /gene="pth"
                     /locus_tag="ROH59_002895"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDX4805351.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGSGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            22746..23024
                     /gene="ychH"
                     /locus_tag="ROH59_002896"
     CDS             22746..23024
                     /gene="ychH"
                     /locus_tag="ROH59_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HDX4805352.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            complement(23079..24758)
                     /gene="dauA"
                     /locus_tag="ROH59_002897"
     CDS             complement(23079..24758)
                     /gene="dauA"
                     /locus_tag="ROH59_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HDX4805353.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCV
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNLEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(24883..25830)
                     /gene="prs"
                     /locus_tag="ROH59_002898"
     CDS             complement(24883..25830)
                     /gene="prs"
                     /locus_tag="ROH59_002898"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDX4805354.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(25981..26832)
                     /gene="ispE"
                     /locus_tag="ROH59_002899"
     CDS             complement(25981..26832)
                     /gene="ispE"
                     /locus_tag="ROH59_002899"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDX4805355.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDIISIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLSTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLS
                     PLHRAML"
     gene            complement(26832..27455)
                     /gene="lolB"
                     /locus_tag="ROH59_002900"
     CDS             complement(26832..27455)
                     /gene="lolB"
                     /locus_tag="ROH59_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HDX4805356.1"
                     /translation="MTLPDFRFIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            27669..28925
                     /gene="hemA"
                     /locus_tag="ROH59_002901"
     CDS             27669..28925
                     /gene="hemA"
                     /locus_tag="ROH59_002901"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HDX4805357.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEERDDLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEIIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            28967..30049
                     /gene="prfA"
                     /locus_tag="ROH59_002902"
     CDS             28967..30049
                     /gene="prfA"
                     /locus_tag="ROH59_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDX4805358.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            30049..30882
                     /gene="prmC"
                     /locus_tag="ROH59_002903"
     CDS             30049..30882
                     /gene="prmC"
                     /locus_tag="ROH59_002903"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDX4805359.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLEHVTGKGRTFILAFGE
                     TQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVALAQRNAQHLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            30879..31271
                     /locus_tag="ROH59_002904"
     CDS             30879..31271
                     /locus_tag="ROH59_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HDX4805360.1"
                     /translation="MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTLLLLSGIALMAKAHIQPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            31275..32084
                     /locus_tag="ROH59_002905"
     CDS             31275..32084
                     /locus_tag="ROH59_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HDX4805361.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH"
     gene            32120..32974
                     /gene="kdsA"
                     /locus_tag="ROH59_002906"
     CDS             32120..32974
                     /gene="kdsA"
                     /locus_tag="ROH59_002906"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HDX4805362.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
     gene            complement(33123..33230)
                     /locus_tag="ROH59_002907"
     CDS             complement(33123..33230)
                     /locus_tag="ROH59_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HDX4805363.1"
                     /translation="MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK"
     gene            complement(33635..34735)
                     /gene="chaA"
                     /locus_tag="ROH59_002908"
     CDS             complement(33635..34735)
                     /gene="chaA"
                     /locus_tag="ROH59_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HDX4805364.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSLWHAIWLIVHLIAVIAVTKMNASPLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
BASE COUNT         8585 a         8426 c         9037 g         8809 t
ORIGIN      
        1 atctgaaatt caatcgagat atagcctatt agaagaacgt taccattccg acctgaagcg
       61 gttggatttt atttccgaag gttctcacta tttcacttca cttcaggaag ttccttgttc
      121 cctttgtgga caaaatttac tacatccaca cagtgagaac gctaaaaaat taatgaacag
      181 taatgaagtc cgacgttctt ctttagctga agctgcaaaa attcatggat accttgcagg
      241 cctgcaaaaa gcgatgagtg atcttgaccg aagaaaagaa gctctgaata tagacagata
      301 taagtcaaaa gaaagcttgg atggaatgaa gaaccagatc aaatatactt ttgagcctct
      361 tcttacactt tccaaagaaa gcctagattt agctattgag cagcgagctg aaagagactc
      421 tgagttgaat gatcgacaga gatggtttga gttactaaaa catcaaaagg atatagaaat
      481 actgctggaa aagagcagtc aaccacggct cgaatgggag ggattatcta cccgtacgct
      541 ggccgaactt tgtagagaaa ttgaaactgt tttaaaagac tggaaatggg gtgccgagcc
      601 tgacgtttca tttaatgaaa aagagtatga catcattgtt gatggacaac ctcggcagtc
      661 tcacggtaaa ggtgttcgtg ccattcttta ttcagctttc atcattggat tactaaaata
      721 ttgtattaaa aaaggatacc cgcatcctgg gctagtcgtg attgattcac cgctgacaag
      781 ttataagaag aaagccgctg ctacggtatc gggcttcgat gaacccatat cggctggtat
      841 tgaggaaggc ttctggcatt cactgaccca attgcctgat accttacaaa tcatagttat
      901 agagaataaa gaaccgccgg tatcaatcat gaataaagtt cattacgaat ggtttgcggg
      961 tgaacatgca atggatggag agcgcagagc ccttatcccg ctgccctcaa aaaatagtgc
     1021 tattttaatg aagtaactta ggatgggtag ccatcaaatc gcagttatac gattggtggg
     1081 gtttgtaaaa gcggtagtct tgattaccac tgcattcatt ctacaagcac atacttccct
     1141 aggttgctgt agttatccga ttacacgcct tttctgaaag cagcctcagg gagccggata
     1201 aaacccgtta aaagtggctt gcctatactg ctgcgcggcg ctgacgcttt agaggcccca
     1261 ggatttaggc aaatcaatgt agttagctca gtagcaggtc atatctgggc tataaatggc
     1321 attacgtgac actgaaagag cttcccagtg gcatcgtatt tggtgagccc caacctacaa
     1381 gacgggcggg gatagccgtg attggcaccc acagcaaggc gataaagatg ttcaacggag
     1441 cggctcagca ggtatgggga tggtaggatt tagtcttcat atgcctgtgg aattaatcaa
     1501 ccctcagagc ccgacacacc cggcattgct tacggtataa gactgattga gaaggtgttt
     1561 gacgtttttg tatcccagtc tgtcggtaaa gtaaacacag tgatcagtaa ctggtagtac
     1621 tggaagtgat tgcggtcgta atgctgattt tgcacgctac gacaggtata ttctgtttgg
     1681 tatctgtaga ggttgtgatg gcgctgacct tgcacatgcc aggtacgtta gacttaataa
     1741 taaagggagt attagcagga gggatttttt cggactcagt tgtattgtgt gtaacgagcc
     1801 aactaaatgt gataatagct ataatggtaa atatgatgat ctttttcata gggtttcctt
     1861 ttggaataaa acatgaatta tttcacccaa aaggaacccg gatgttattc agtgattata
     1921 aacctgttac gtttatataa aacggacctt taccctcatc agttttctga atccggtagg
     1981 tgattggtag agaattttgc aaatctggtt ttgtaaacgt taaatcagca gcgcactgat
     2041 aaacatccag atctgattca tggctaattg ttctgacatt ttctacagaa atacgcacat
     2101 ccttatccag tttcatccct ttctcgattg tctttcttgc aatatccccg accagatttt
     2161 ttgcatcatc actactacat tttggcgttt tctcgccgca gccagccagc aaaccagcag
     2221 caattaatac cagaagtatt gctcttttca tctgtagttc cttcgtaaat taatgatact
     2281 tttatttctt attaaataga ccatccattg cgcctgccgc agaagccccg cagtatccct
     2341 cgcaaccacg tgtcataatg ctggccttac cgtttgtcag ttcactaatt actgcaacac
     2401 actcgctggc attgtcattc cagacccagc gacgcttctg actttctccg gcagctattt
     2461 gctgtgctgt cccctccata ttgcatacgc ccgaaccatc ccccgttgag gcattaatgt
     2521 tgaattcagc gttattctgt cccggatgca gggttagaac cgctccgggt tttacgtact
     2581 gcgctgctgc gactggtagc gttatggctg ccatgaataa ggccaacagt tttctgttca
     2641 ttaattaatt ccctgttaag tgatacggat gtttttggtg attttcccca gtgccagcgg
     2701 tctgcgtttt tccacaaaga aataaacgac gttgaatgca gacttgcgat gattccctcg
     2761 accaagagag ggccagttgc ggaaggattc aatctgttct tctgaatagg gtgtgtcaga
     2821 gaaatcaaac agcacaagca aggctttgcc gtcatgtttc atcaatttct ttacttctgt
     2881 actgttgacg gtcgcagaga cattggaacg tgccgcagtt ggtttacgta ctgcaaactc
     2941 aacggccaca tcgtcaatga caaaatcaat gtaaccgtgc ccggatacag ttcctggcag
     3001 tttgcttttt acttccggtg agacgttatc tgcaaaccaa cccagcaaat agcaacgtac
     3061 cagaggcagt aattcccgct cgctacattc gttcagacgc agggttttga cgaactccct
     3121 gcgataaaga gaactgaaaa aatactcaaa gcattccgtt atttcagtga tggtggttgc
     3181 catggttgca tcctttacct gctattaggt ccatttttaa gggcatacct ttccggccat
     3241 aatgtttccg gtgtcgtatc cagagccccg gcaataatgc gctcagctct gggataatga
     3301 cgctctaagg cgttatttaa tgtccgtggc gcaaggccgt gactgcgtga cagtaacgcc
     3361 agcgttaacc ctcgcttgtg aagtgctgcc acaatatcgg cacgatgcca gttccctgaa
     3421 cttcctttga tttgcttttt ctgcgatgct gttgagttac gcacagtatt aactccatgg
     3481 aatcagtaca tggatattaa atgcgaataa aagatacctt tcaagttctt ttggtatcta
     3541 tttattggtt ttcatattaa cgcattgata tctggtgaaa tttatatgag cagtaagaga
     3601 acagtttcgg ctatacctac tcatcctgaa gcttctgttg aagaggctaa agactggctg
     3661 acagcagagg aattcactca tattgagggg atgccgggca ctgcgcgtgg cgccaggatg
     3721 cgcttggaaa agctggcatc cctgcacccg gaaatacgtc gtaaaaggac tgccgggaaa
     3781 ggtgtggttt accatattag cgcagccaca atgtcgcttg atgatgagag aaacagggct
     3841 aagggcgaag cgtttactct caacgacagt gatcgccagc taagcctctg ggtgcagctg
     3901 tatcgcaata tgtcgccagc ttcgcgggcg caactgatgg agcaggccct caggctggta
     3961 aaggacgatc tgatgtctca ggggcccaat gtttctgaac tggcggtaca aatcatgaag
     4021 ctgcccgaag atgagcgtaa gcgcctcttt gaaaagctga acgggaaggt gtgatagcgt
     4081 cagttttccg ccatgccaga cagaaggaac caccccggaa tcctgacctg tctgacatgg
     4141 cagaatggaa agtatgccat cacttaataa tgaataaaaa cctattgcca gttatttcat
     4201 tgctgaacca catattagtt tctctttgtt actatttgca taaaaagtat atttttgata
     4261 taataatatt gctggtgaac tatattttac ccagtcagta cgttgtcatg cacttaccat
     4321 ttattaggtg attaaacccc acctgtgctg gtgcagacat aacgtcttat cagaatatat
     4381 tgaacaggaa aatcactgat gaatattgtc catcaggaag ggctagctat gcccgtcgat
     4441 caggaattaa taaatatcat attaaatgaa gcgggaaatc caccgccgca taaagccaaa
     4501 attacagccg tcagtctgtt atttaaagac ctgagttaca gcgctgaaaa gggtggttac
     4561 catcctgtcg aaatacggat tatttcacgc aatgatgaat ggtattttga ttacattacc
     4621 gacttcagtt atatggggac ggtatacccc gaacttgaaa aggaaattga tatcagctgg
     4681 agtcagcaat atgtctttct tgcttatgtt ggtgacctgc ctgttaacgc cggaagggag
     4741 ctgtttgaac tctggcaatc caactttatt cagtatcacg gcatgaacat ctacaccatt
     4801 accgttctct gggaaagcta atccccctgt actaaccatc actaatttat ggggaattat
     4861 ctgtgacgac tgacagaggg atacgtgcgt ctcaacaggg cgaactggac tgtctttgcg
     4921 gtgcttattg cgtggttaac atgctgagct ggctgtatga cggcagggtg aaacgacgcc
     4981 cgttaatgaa ctggcttatt cagacttatc agcagcgctg gcctttgcat gaatggctga
     5041 ctgaaggaat tgaagaagac cgcttagact ggttaatagc tcaggtgttg cagaaagggc
     5101 attaccgccg ccagttcccg gttgaaatca ccagaccctt tgcagggaag cgggggttaa
     5161 cagacgggcg gctgttcagg gaaatgcagc ggtttcttga cgtcactgac cactctcgcc
     5221 tgattatgct cagcgaccag tttcactggt cccttctggt caaaatggac gaagaaatgc
     5281 tctgcttctt cgacagcaac gggcgaacca ccatgccccg taaagctttc tccctgcgta
     5341 ctggcgtaac ccgccgccag ctgtttccag acgccattta cttcattgaa cgggagttct
     5401 gacatgacca tgtttaccca gcgtgaaacc cgtatccttg accaggcgcg tgacattatt
     5461 agccggtact accagcgtgg ggttcaactc tgttcccctg atgatgttcg acggtgcgtg
     5521 atggttgagc tggcaccgct tgaacatgaa gagtttggca tcatcctact cgataatcat
     5581 aatcagctgc tgcaccgcga aatcctgttc aggggtacgc taaactcggt cagcgttcac
     5641 ccccgtgaag ttattaagcg tgtgctgaaa cataacgccg ccgccgtcat ccttgtccat
     5701 aatcacccca gcggcgagcc tgaacccagc cggtgtgaca tccagttgac caaaaagctt
     5761 caggagctgc tggaaatact ggatgtgcgg ttacttgatc actttatcgt ggcaggaact
     5821 gaaacggtgt cgatggctga gcgaggactg gtgtgatgct gaaagttact tggtttaatg
     5881 tacgttattg cgggttacgc gcatgagcag gacagcgttg cgtcaggtcg tgccggtggt
     5941 gcaaaccacc gtgttcgatg cgtatattgt cggtctggcc ccctcgggac ggcgaggtat
     6001 caccagcctg ttaaaccgca gcgccagcat acttaaacac ggtgcggatg cagcagacta
     6061 tccgtgggaa caacttaact acgccgccgt tgccaaagtg cgcgcggcac tgctggatga
     6121 cggttacgcc gtgtcatcgg tcaacatggc gctgtcagca ctccggggcg tagcgcagac
     6181 ggcctttaac ctcaattaca tggatgccga aacgctggca cgtatccggt cagttaagcg
     6241 cgtgagcggc gatgtccagc gcaagggaag ggcgctgggc aggcaggaaa tccgggtact
     6301 gattcaggct gcaaaacagc atccgcaatc tgtacggcgc tgtcgcgatg tcgccattgt
     6361 gctgatgctt tgcggaacgg gcctgcgggc cggggaactg gttaaacttg agcgccggga
     6421 ctatgacaac ggcatcctga cggtgaggca agggaagggg cgtaaatacc gtgaaattca
     6481 cgtggcggat gcggtggaca aggctattcg tgcgtggctg aaagttggcg cagacgaggc
     6541 tgacagtgcg ttgtttaggc gaattcagcg cagtggtaag gtcgcaagcc aaccgctgac
     6601 tacgaccggg ttaacgggta tcctggctga gttacagcaa acggcaggta tagcacgttt
     6661 taccccgcat gatatgcggc gcaccttcat cacccgtttg ctggagcagg gcgtggatat
     6721 caataccgtc cgccagttgg caggccacag cgacatatcc acgacgacgc gctatgactg
     6781 tcgtggtgat actatgaaga tcagtgccag caagcgcatc agatgttttt agcagttgag
     6841 gcgttgccag actcggtttc agtttcatct tcagcactca accgcgcgta cttttgattc
     6901 tggatgttaa tttgtgcatt gatattttca ggctgaagca tccacgcaac atcctcacgc
     6961 gcccattctt taccgtcaga gagtcgtttt aaccggggtt tccatattcc atactcatta
     7021 agtttttctg ctaccgaagc atatttctca cgatctgact cccccgtatg aagcttgtca
     7081 aaacgacctt ttacaagctg gtaaacagta tagatttcca gtgccttagg ggacctggcc
     7141 gggactatca tggggtgttc ctccggccta taaatcccgt ttggctctcc ctcattgagc
     7201 aggtcattaa acatgtggtt cacgcaggca ctcagcacat ctgccgcttt ctccgcagcg
     7261 aatttatccg ggctaaaacc cgctcccgtc agtttccggg caatcagtgc cagtttttgc
     7321 cgggtatccc gtcccagata aagcttcttc tccagaaatt caaagacctc gttactgctt
     7381 ttccgttccc ggtggcatct ggcgtcagcc ttgttgcttt ggttaccaat catagtcacc
     7441 tccatgacag tgttttgtac aaaatatcac cattgagcct cagtgaaaat tgcttcttta
     7501 tatgaccgtt ctggagacag aaatagatga tctcgaatga catccacatt aaagatgccc
     7561 ttaacgtgct caacgaaggc atcgttgagt gaatccttgc gttttttggt ggttgtaaat
     7621 aacccgctcc tgaaacagct caaaggagca caagcatgaa caccaaccgt attttgcgta
     7681 aaaaagaggt acttcatctg acggggaact cgtcagcgac gttgtaccga ctcatctcga
     7741 aaggattctt tcctttgtca aagaggctaa cgggcgacaa tggccgggcg gtaggctggc
     7801 tggagagtga tatcaataac tgggttaaca gccgtatgca ggcgggagaa tgaaatgaaa
     7861 gagataaaat cgaaaaccag ttctgcgaaa aaaacgctgg ttccttggtt cgaaactatg
     7921 gggaaacagg ttggtttatc acaagaaacg atatcagcag tgttaaagga gcagcgttta
     7981 cggatacgta agcttaacta cgcatctgca tatacagtgt ccaatattct catacaggat
     8041 tgcggcgggg ccgatgacat gtggagcaac tacgctaaac tggcgcttat ccttgagcgt
     8101 tgtaaataca ttccctgcgg gagcagggcc tgtgcatatt gttctaccgc tcagcaatta
     8161 cattatcagg gggtggatgt aaccggggaa tacgctttat atcagttgcc tgagttattt
     8221 ttagattttt tagaaacaaa cgacaaaaat tcctcttatc attgggatta caataagtta
     8281 gttgagcggc atgaagatgc tcaggcgagg tcattcgggt aatagccatt tctgtatggt
     8341 gaaaaactga catattaccc tgccactgca ttttggtggc agggtaatca atacagctag
     8401 gaatattaaa tgaacgattc ttattacttc agaacatctg acccggatta cattcgtcac
     8461 gcaccgtcaa tgcttgagat tttaagtaaa gcattcccca ctattattac ccagcaggaa
     8521 agtgagtatg aactgcagcg tcttaaccat ttactaaata aactgaaagg cagcaatcgc
     8581 tgctacaaca tcattgctca aaaactaagg cagtgcagaa acggatctcc atgcaacagt
     8641 cttatatgcc cgcattgcca gcgggaacgc attctggcgc aactggctat gttgcatgtc
     8701 ttgccgggga attcagcaga atacgtggga gtggtcctgt ttttcaacaa ggatacgcaa
     8761 actccgccgc catggaagaa cattggggcg ctcagggcgc aaatcggtcg ttataagcag
     8821 aggataagcc gggtacttaa ccgcctgggg tacgccggtc cggccacagg caccttcagt
     8881 atgatgcgac atatgcctga tggcccagaa gagcgtattt tctgggttcc acagttgtgt
     8941 ttgttcctgc ccaatgacag tacgttgatt aaggggctaa aagcgcatat gtcgcgaagt
     9001 ggtggggcat tcattgatgc atcgacgctt aacacaccag tgatcgtgct caggtataaa
     9061 gatcccgcga gactgatttc atgcgccctg aatccagtct ggcacacagc agattacaca
     9121 ctgactgata aagacgctct tgttaagtca agaatggagc tactgaaagg ccggacactg
     9181 ttaaaaagtc tgcttaccct ggactcactc ggaacaggtg tcgtttcttt ttcgtttggg
     9241 caacccccag ggaaagtgca ctgatttacc ggtaatgcag caactgcaat gcacttttgc
     9301 tgttgattaa attgcagtgg aacgacgaat aacagcggca accactgcat tttcgttgtt
     9361 gtaaaactgc aaagcttgcc agtgattttg atggcgctga tgcactttaa cattccaact
     9421 gtctcgattt taacgcaacc gtctgttttc tgcaggggct cacggatgcc tctgcacacc
     9481 cgatccttac catcaactga cgagttagcg catctgtgag ggctttctgt gtttctgtca
     9541 gtgaatattc tacacacaat ggggggagcg gtcagcgagc accattgcca ttgagcgcaa
     9601 cggagagctt ggggacatgc agcactacgg aggcttcatc tccttctcat gtcattaaac
     9661 gatacggcga acgagcgcag cgagtgaggg aaggcgtcag cctgaacagg gggaaagatt
     9721 tgcgaccgga gtggagcaaa tcatgggcgg agcccatcct cgcgactggg gttttgactt
     9781 tcgaattgcc cagcgttgag tttggttaat gtagtgagac gaggatgctg agaggggacc
     9841 gtgagtactg aaaaggatta tccagtgaag atccctaagt gggtttatga ccgtattact
     9901 gaaataacgg attatgtcgt gggggatacg caatgggctg ttacccggcg gcagacagta
     9961 cggtggttcc tggctcacat atggctggaa acagacgatg atggctggac tatatgcact
    10021 gtccgggata tccgtagcag ctatgccagt ctcctgggac agtgtgaaat tagttaccag
    10081 ggggagtgct ttatgtccac gctaactgat ttcctgccga cactttcgga tattgaattt
    10141 cgtgcaggaa aagcgagcaa agacccggaa aagcgtagag ccagtgcatg gcggttcaac
    10201 cccctgctgc ctgtgtgtga tgagtctgcc aggggtaagt taaatctggt tgacttggat
    10261 actggtgagt ctgttagttt tagagctctg cttcagggga acgggaaagc tcctgggcat
    10321 gcgatagatg tagagaaacg ccagacggcc ctaaaacaaa cggaaaagga cttcttggcc
    10381 aaagttgggc gggggcgcat gagtatacag tttgtgaagg aattgcgtag ccgtgagccg
    10441 gatcactatt accgcgcagg aatacgcagc cttaaccatc tctacaatgg caggattgag
    10501 ggacaatatg tcacttacga ccatcattat cgtctgacgt ttggagggcg gtattatgat
    10561 caagctttcc agaatctgcc caatgagttc aaagctaaat ttcggaccgg gttactcaac
    10621 tatgacatcg aagcgtgcaa tctggcctgt ctgaaccatc tgttcagaca gtatgacgtc
    10681 gattatcgtg tgaagtcatc gatatataaa accatgatgg aacataccgg gctgacccgt
    10741 aaacagtgca aacagatggt ccataccacc acctacagaa ttgggcgtgt gactattggt
    10801 gttaatgatg gccttggggc aaaagtgtat ggatggtgcg gtaacagcaa aaaaaaggcg
    10861 ctaaagattt tgcgttggtg gaaccgttat atcagtccat tgaaatctgc gcttgagtca
    10921 ttgctggaac gtgtgcatgg cgcacaccgc aagagttgtt catcaccgcg taactatcac
    10981 aggtacgcta atgaagtcgg attaatactg gatcttaata gtgaggtgta tcagcgtgaa
    11041 aagactcacc atcatcaata tgcgcggaat aaggcactgt tggcgtttat gatctgtggt
    11101 gtggagcagg cgtatatccg tgaggttgtc agtatgaacc ctggtcgtgt ctgcatgctg
    11161 gatcatgatg gggtagtggc aacgggcgcg ctttcactac cggactggcg tggtttcacg
    11221 atgaaagtga aggactagct tactttcttg aatttaacta tctgcgatct ctgataaggg
    11281 cgtattacgt tgtcaatcat aatgggatat gcgcattgga acgatgtgca tatccagtaa
    11341 gtgatccatg tccgctttga gctgtgagtt caacgggtcg atgcaacgct gtccctaatc
    11401 aagggggacg ttgccatgaa acgaagaact cgtattaact acacgccaga gcaaaaggtg
    11461 attatttggg acagatataa gcaaggtgat tccctgcatg atatccccca gaatgttcga
    11521 cagatttcac tctactatca tgcctacaat ccaccaggcc ggtggctacc gtcctcccgt
    11581 gcgaaagcgg caccggttag cgttttcgct tgatgaaaaa gaggagatat ccagaggact
    11641 ggtagcaaaa cgcatcatca gggacatcgc tgctaaatta tcaatagctc cctcaacgat
    11701 tagccgcgag atcaggaggc acggcggtgc aaaacaatac cgtgcagcaa aagccgatcc
    11761 tgctgcgtgg gaaaatgctc tgagaccaaa accttgcaag ctaattgaaa gccccacatt
    11821 gtgtaaaatc attgcagaga agatgcatca ggactggtcg ccggaacaaa ttggcggttg
    11881 gctaaaacgc tgttatcccg ataatcagga aatgcatgtg tcacatgaaa tgatttataa
    11941 aacgcttttt ataccaaccc ggggagcttt aaaaaaagag ctgcagcaat gcctcagaag
    12001 cggaagagta gtgcgtagat ccaaaacctc atcacttaaa gtaaacagag atacattctg
    12061 gtcacgaatg cccggttgtt cgtgctttgc gttttaatcg cattttacag tttctgcctg
    12121 cgtgcagagg ttgatggtat tttctgaaaa agcggctcgc tttgctaatg catatggcac
    12181 aaatacaaca gtttgtgtca ttctgaccca tctttatacc gcgacggtgg aaacatggat
    12241 gagctgctaa cccttggctg cattgcttta ttcttcgcac tggtggtggt tcccatcctc
    12301 gcgattatcg cgctcagccg cagcacggct gttcgttctg agctggcgac cctgcgtcgc
    12361 cgggtggagg tgcttgagca gcgcggtgtg actgaagcac ccgccacagt ggtaacaact
    12421 gtgccgcaga gtgtttcgca gatggttgtg cctgttgaaa cgtcttcgcc tgcggttaac
    12481 atcgtgctgt cggagcctgt ggctgatgtc acgcctgagt ccgttgaccc ctggcgtcca
    12541 caaccgaagc cgcaaaacga ggcgctaccc acaccagcgg tcgaacaatc ttccgctttt
    12601 ggtggggtga tgtcgtccct ggtgcgctgg tttatgcagg gcaacccgct ggcaaagctg
    12661 ggtattctgc ttctcttcct tggcttctcc ttcctgctgc gttatacggt tgaacactcc
    12721 ctgttcccgc ttgagctacg tctggtggcg acttcgctgt ttgcgattgc cctgctggta
    12781 gtgggctggc gattgcggca taaacagctg gtttatgcgc tgatcataca gggtggagct
    12841 acggggacgc tctatctcac cgtttttggc gcattctggc tctggcagat gctgccgatg
    12901 acgctggcgt ttgcattact ggtggcgatt tgcgcggcga gcgtgggact ggcgattatg
    12961 caaaaagcgc tcagcctcgc gatgctggca agtatcggtg gctatctggc accgctgttg
    13021 ctttccaccg gcggcggtag tcatgtggcg ctcttctctt tctaccttct gctttccgtc
    13081 ggtattctcg ccatcagcat ctggcaacac tggcgcgagc ttaatctgct tggcctgtta
    13141 tttacctttg gtatcggcgg tctttgggga ctcgacggct atcgatcaga gtattacctg
    13201 agcagtcagc ttttcctgat agccaatacg atcatttttg gtgtgctgag cgtggcgcta
    13261 tcgctacgag cacaggagaa aggtaagcag attattgatg gcgtgctgtt gtttgcatcg
    13321 ccgctggtcg gttttggcat gcagtacgcc ataacccggc atatggaata tggtccggcg
    13381 cttagcgcgc tgggttacgg cggtttctat ctggcgttag catggcttgc attgcgtcgc
    13441 tatccctctt tggggaggcc gctggtgctg gcggcgctgg cgctgggtgg ggcatttacc
    13501 acgctcgcta tcccactggc gctttcggcc cgctggacgg cgatggcctg ggcgctggaa
    13561 ggtctcggca tcctctggct gggcgtgcaa cagcagcagc ggcgtatgag ctatagcggc
    13621 actgcgctgc tggtgctggc agtgtgcagc gcgctgtggg cgcagatgaa cgggatgagc
    13681 gcgctttctc tggtgctaat ctttgccgta ctcagcctca gctggctggc tgccgcctgg
    13741 ctgtggcgca atattcagtt gcagggtagt tgggttctgt tggctggcgg tttgatcttc
    13801 tggataatcg cgctcattgg ggcatcgcaa ctggtgctga aaaaggactc gctggtgctg
    13861 tctggcgtgc tggcgttaat ggcgatatcg gtctggggct ggcggattgt ctctggtcgt
    13921 ctggcctggt gggagctgga tgtcagcaaa tggttgctgt ggccgacgat gctggtgatg
    13981 ctgctgtctc aaatttcaca acatgagatt tttgctgcgg gctggcagaa tctggcctgg
    14041 tgtctggcgt tacccgctgc gggggcattg ctctggcgtg atgctgagac gttgccgccg
    14101 cgcctctcca gactggcgca cctttcactc ttctggatga ttctgctcgc gctggcggcg
    14161 gagctattct ggtttgcgca agatctgcca tggggcatgg cggcgtgggg ctccggcctg
    14221 atgatggccg cggggggcct gctcatcttt ctcgttcatg aggcggttca tcgtcagcta
    14281 tggccattcc gaagctggcc cgcactctac gcttctcagg cgatgatacc ggtagctgcg
    14341 gtattggttg ttctgctagt actgacgaat ttgcaggatg gcgtagttta tcgccagacc
    14401 tggctgccgc tggtgaatcc actggaggag ggggccgctt ttgcgctact gggactcatt
    14461 gtattttatc gcgtttcgca gcgctttttc ccggtgcaga tttcggtatg ccgtccctgg
    14521 ccgctcattg cactgctggc gcttagcttc tggtggctga atggcatcct gctgcgcgca
    14581 ttggcctggt acggcgaagt gccctggagc gcggaaacac tgtggcattc gcggctgatt
    14641 cagacctgtt ttgccctgtt ctggatgctg gcggcattag tggtgatgct acgtgcgacc
    14701 cggcgttgct cacgtcgcga atggctttgt ggatccgtat tgttagggat tgttattgtg
    14761 aaactgatgt tggtagacag tgcgcgtggc ggcggcctgg cacgcgcggt cacgtttatc
    14821 ggcgtggcaa ttctggtgct aatcgtcggg tatttttcac cgttaccgcc caaagcggga
    14881 gaagaaaaat gaaatggatg aaagcggtgt tatgcagcgt gctactgagt actgcgggcg
    14941 cggcggtcag cagcgatgaa gtgaaggaag cgccaacgga ctacgcaaca ggcgtcgcgc
    15001 tggaaaccac gggggcattc gccctggtat cgcatttcgc tgccgcaggt ggtgtatcag
    15061 agcactgcat ggccggattt gcgcgatgtg cgggttttta accatctggg ggatatggtg
    15121 ccgtttgcgc tggtggcgca gaaaacccag accgttacgc cagagacagt ggctctgcgt
    15181 cttttcccgc ttgatatgtc gccggttccg ccgcgtgatg agggtcaacg tagtggggat
    15241 gctgttgttt tacgttcaaa aaacggtatt gaaattcatt tgcaaagcga tgatgtcact
    15301 gcgctcgggc agagctattt actgacgttg ccggaagaga ggaaagactc tctttcactg
    15361 acgcaattgc gtctgaactg ggggacgccg acgggcaact ggcaggggaa agcctcggtt
    15421 tatgtcagcc gtgatttacg ctactggcga cccgtgcagg aagatgcgcc gttaatggat
    15481 ctgacgcggg atagcgatcg tctgaaaatg gacgccatca gcaccaacct gacattgtca
    15541 cttgaaggaa atcgctacct gctggtgatc ctcaactcgc aaagcccggc actgacgtta
    15601 aacagcgtga gcgctattgc tgacagtaat gagccggagt ccgaacgtat tgtgattggc
    15661 gctcgggcgg ataaggtgtc ggatgatgaa gccgtctggc gatggacaca gccgcagccc
    15721 ctgacatcgt tgcggatcga tctggaaaat gaaggcgttt taccggtgga actggtctgg
    15781 cgcagcggcg aaaaagaacc ctggcagtca ctgacaaaaa cggtgttgta tcgcctggac
    15841 gggaagcgtt cagaagatat tcgtcttcct ggccagttag ttgaggctgt tcgaatacgt
    15901 acaattaatg cgcgattgcc ggaggcattg ccagcattga gcggtgcgcg cgacagttat
    15961 caactggttt ttaacacgca aggcaaaggt ccttacatgc tggcgtgggg aaaccgggcg
    16021 gcgaaaaagg ccgatgttgg actcgatatg ttgatccctg cgtcgctgcg taaaacgcag
    16081 gagatagata atctgccgtg ggctataccg caggagagcg taactctcgg cggtgaattg
    16141 cgactaacgg cgacgtcggc agccgaacaa caaagtcagt ggaaaacgct gctggtgtgg
    16201 ggggcgttaa tacttggcgt tgccgttctg gcgtttatgg catggcgaat ctggcgagaa
    16261 gttaaaaagg acggtgcggc gtaagccata aaaaagcaca gttgcatagt tcacggtgtt
    16321 gataaactgt tacaacagag gcgtttaagc tgaggcgggg aaataatcta tttgtgaata
    16381 atatgttact tcactggggc gtgagtcatg ggaatgattt tgatacctgc gttttttatt
    16441 ttagccatcc tgattatcgc tatcttcatt tcagttaaga atggccgtca cgtatccgtt
    16501 gtatgccttg ttgccgtggg tgagattttc gtattcccat tctattttac ggcccttaag
    16561 cgtttccgga gcatcaaaac ttggtaaaga tttaccatgt tgacccatta tgcggcccct
    16621 ctggagacca ctttcaggta ttttctctac tgatatgtac acatggagag atgtgattgc
    16681 aaattcccat cagcattact accaaaagaa tcagacagga agcagcatag tattaataag
    16741 aatattttca aacataaagg atgattatga gtaacccagg cccacttgca gcgttagtgt
    16801 atggttttat tttgatagtt ttgctatcgg tatctttaat cctttattca attggacgta
    16861 ccataaaaaa cgagattgga aaaggtatag catacgcgct tactggtatt ttattaattc
    16921 tgtcattatt agttggcgct ttcattttga cgcttcttac ataaattcct cgaaaaatac
    16981 gctgacagca tcagctaatg gacccgactc tccgttgaac gcatgctcgc ctgcggcacc
    17041 tgtgccatgg gcgtccgccg ctacgggcag gcatcaaggt tcgcttcaca acagcggacc
    17101 tgctgctaca gctatccact tcatagcgcc agggccgtta caaaacgaca ctcaatcgcg
    17161 gtgtcatggc cccgaagcta cttatcatcg atgaaatagg ttatctgccg ttcagtctgg
    17221 aagaagccaa gctgttcttc caggtcatcg ctaaacgtta cgagaggagc gcgatgatcc
    17281 tggactccaa cctgccgttc gggcagtggg atcagacgtt cgccagggat gcagccctga
    17341 catcggcgat gctggaccgt atcttacatc actcacacgt agtccagata aaaggagaga
    17401 gctatcgact gaagtagaaa cgaaaggccg gggttatacc tgaagctaat cctgagtaaa
    17461 caaggtggat caatattaaa ccgttggtgg tgacggttag tggatcactt tattacccgt
    17521 tgttgacagt aaacgcagga agtcagatgt gatgcgccga aagctgcttt cgcacatgtt
    17581 acagggactg gaaagccggg ctgtttacga ttacgttgcc agtcataagg gcgtttgcgc
    17641 actggagcac gatgggtttt tttcatataa agaggtcact gactggtccc atccatatct
    17701 gttgattgag aaaaagcatt aaggggagcc actcagtcaa ttacagctta tctcggttga
    17761 taaacaagac gggacattta gcactttcat gatatgcata gccggcaggt gatcttagcc
    17821 tgctttcagc gatgaaccac acaatattcc ccttttgtta ctttgatatg attgctcaaa
    17881 atgggtggta acactgagat cgttgaaatg actgcatgtt atattgttac ttttgttacc
    17941 gttgaaaaca tcacgttgga gagctaaatg gattggccaa aggagtacag caagacgact
    18001 caagtggagt gaccacattc cggtagacag tttctgtcct cacggtgagg ccttttcgaa
    18061 ggcctccggg ctgacgccac ccagatgact gtggcgccgg gtccggttgt agaacacttc
    18121 aatgtaatcg aagatatccg cccgggccat gtcccgggtt ttatatatcc gctttctgat
    18181 gcgctctttt ttcagtgaac tgaagaacga ttctgccacc gcattatccc agcagttgcc
    18241 acgacggctc atactcggcg ccagattgtt ggccctgcag aaccgctgcc agtcatcact
    18301 gccatactga ctgccctgat cgctgtgcac tatgacgttt tctgcaggct tacgccgcca
    18361 gactgccatc agcagcgcat ccagtgccag ctcgcgcgac agcgttggtt tcatcgacca
    18421 gcccaccaca ttacgggcaa aaagatcgat aaccaccgcc agatacagcc aaccctgcca
    18481 ggtgcggatg taggtaatat cagtcaccca cacctggttg ggttttacca tcgtaaattc
    18541 cctctgtacg cgattaggag ctatcagtga cggccttccc ctgacgccac gcgggacctt
    18601 atagccatgt acggcctgta tcctgttccg cttcatgatt ctggcaacac ggtttctgct
    18661 gcatacttca ccgatttcac gaagatcgcc gtgaaccctg cgataaccgt agactccgcc
    18721 gctcagtgca taagcatcgc ggatgagctc cagcaaccgc tgattatcct tttctccggc
    18781 agaaacaggg cgatgaagcc agacgtaaaa tcccgcacgg gcgaccttca gaacccgaca
    18841 cattgttacg atcgaccaga tttcacggtg atcgttgatg aagcggtact tcagtcgggc
    18901 tcccttgcaa agtaccgcgc tgcctttttc agaatatccc gttcttcctc agtacgttta
    18961 agctgcgctt taagcctgag aatctccgtc cgcgcatcca gtaaatcctg cgcctgatgc
    19021 ccgctgttat ccggtctgac tgaccggacc cacttataaa ggctgtgagc cgatacgccg
    19081 aggcgttcag aaacatcggc aacggaatag ccccgttcag tgacctgacg gacagcttct
    19141 tccttaaact ctggggtaaa tcgtggtgtg cccatagact cctcctatgc tcaaactata
    19201 gggcagattt gtctacgggc ttgggggcac tccagaacct tgaggaataa gttctatcct
    19261 cgtggttcac tttgtgcagc aagttctact tgaatcctgc tacccatttg tccaacatat
    19321 cagcccattc ctgcatcatc actttacgct catcaagata agttgcatgg ttgtatgtgc
    19381 gacgaacatt gttggtatca gcgtgcgcaa gttgggcctc aatagcatca ggtcgatagc
    19441 ccaactcgtt taaacgggta cttcctgtgg tccgggttgc atgtgggcta tatgtaccac
    19501 tccagccgag gcttttaagt agctggcgca gtgagtgcga tgtcattgga cctagcggat
    19561 tgtctctgcc cgggaaaagg tgctgccgat gcccggttaa tccctgtagt gttctgagca
    19621 ttttgacagc ttggaagggt aggggaataa cgtgttctct gcgggctttc attcgcgctg
    19681 ccggaatagt ccatagggcg ttatcaagat tgaattctgt ccattctgct tcggtggctt
    19741 ctgcaggacg cgccaatgtc caccacataa gccacatgca atagttaacc tgatacgagc
    19801 cacgactatt gtcaaaacag cttagtaact ttccgatttg ttggggattt agtgcctgtt
    19861 tgtgctgtgt cttattagcc ggaagggcct tgcgcacagg ccatacggga tcgctatcag
    19921 ctctaagcgt cgcgactgcc aactcaaaaa ctgatgaaat ggtgcgacgg gcttcagcgg
    19981 caactgttgg tgctcctcgt ttagcggttt cctgaagaat tttaagtata tggtgtggag
    20041 tgatctctct gacagggagc ttaccgatgg cgggaaaaac cacacgttca agcatatcca
    20101 gtcgccgcgt tttggtaatt ccggcccagt ctttcatctg caaccattct ttagcgatta
    20161 gctcaaaggt gttggatgcg tcgttgacct tgcggatctt atctaactga cgagcctgtg
    20221 ttgggctaac tccatctgcg acttgcttac gcgcttgctc gcatttctcg cgagcttcgg
    20281 caagttttac cgtcgggtac tcacccagcg caaacatgct ggatttaccg ttgagtttaa
    20341 accgatagcg ccatgccttt ttaccattgg gtttcacttc gaggtagaga ccattgaaat
    20401 cattaagtcg atagagtttt tctttcggct tagcagtgcg gcattgcgta tcagtgagca
    20461 taacggggcc ttgtttattt attataccgt tattgtactc acttaaaatg aagatggaag
    20521 aatgttgtac tcatccatgt actcattttt gacagcgttg ttatgagatg aattgagaca
    20581 ttgcgaaatg aaaaatccac gcaattgcgt ggattttata gagttttacg gttcttatga
    20641 gattcagtga aacctcatga gacagcagat ttaatttaga cgttgaacag gaagttcatc
    20701 acatcgccat ctttaacgat gtaatctttg ccttctgcac gcattttgcc tgcttctttc
    20761 gcgccttgtt cacctttgta agtgatgaaa tcttcaaacg agatggtttg tgcacggata
    20821 aagccttttt caaaatcagt atggattttg cccgctgcct gcggcgcggt tgcaccaacc
    20881 ggaatggtcc atgcacgcac ttctttcacc ccagcggtga agtaagtttg caggttcagc
    20941 agcttataac cggcacggat cacacggttc aggcccggct cttccagccc aagctcctgc
    21001 ataaactcgt cacgctcttc gtcgtccagt tcggcaatgt ctgcttcaac agcagcacaa
    21061 accggaacta caacagaacc ttctttcgct gcgatttcac gcacctggtc aagatacggg
    21121 ttgttttcaa aaccgtcttc gttgacgttg gcgatgtaca ttgttggttt tagcgtcagg
    21181 aagctcaggt aacgaacagc cgctttctct tcagcgctta aatccagcgc gcgcagcata
    21241 cctgcgtttt ccagctgggg caggcatttt tccagtaccg ccagctcggc tttcgcgtct
    21301 ttatcgccac ctttggcttt cttctgtacg cgatgaatcg cacgttcaca ggtgtcgaga
    21361 tccgccagcg ccagttcggt gttgataact tcaatatcat ccgccgggtt aactttgccg
    21421 gaaacgtgaa tgatgttgtc attttcaaag cagcgaacaa cgtgaccgat cgcttcggtt
    21481 tcacggatgt tggtcaggaa ctggttaccc agaccttcgc ctttcgatgc gccttttacc
    21541 agaccggcga tatcgacaaa ttccatggtc gtgggaagtg tacgctgcgg ttttacgatt
    21601 tcagccagtt gatccaggcg agggtcaggc attggtacga cgccagtgtt cggctcaatg
    21661 gtgcagaatg gaaagttggc cgcttcaata ccggctttgg tcagcgcgtt gaacagggta
    21721 gatttcccga cgttgggcaa accgacgata ccgcatttga atcccatgat ttaaatcacc
    21781 ttaatatctt aataatcaac ctgttattgc taacagattg cagaaatgga aataactttg
    21841 cctattatac acggcactcg gcaaaaatgc cgcagacaac gacttattgc gctttaaagg
    21901 cgtgcaatcg gttcgttgct ttggtcaagc catctgtaaa ccacatttca gtacaacgcg
    21961 ccgcttcgtc gatggcttca tcaattaact tctgttcact aacaggcggt ttgcctaaca
    22021 caaaaccgac aactttattt ttatcgcccg gatgaccgat tccgatgcgt aaacggtgaa
    22081 agttagggtt attacccaat ttactgatga tgtctttcag tccattgtga ccaccatgac
    22141 cgctacccaa cttaaatttg gcgacgccag gaggcagatc cagttcgtcg tgggccacca
    22201 gaatttcgtc cggattaatg cggaaaaaac tggccatcgc cgcaacggct ttgccgctga
    22261 gattcataaa tgtagtcggg actaacaggc ggacatcttc gcctccaagg gtgactcgcg
    22321 aagtataacc aaagaattta gcctcttcgc gcagcggagc gcgcaatcgc tctgccagta
    22381 agtcaacgaa ccaggcacca gcattatgtc gcgttgcggc gtattcagca ccggggttcg
    22441 ccaggccgac aatcaattta atcgtcacgt ttttttgtcc tgagtgtgta cataactggc
    22501 gcgtagttta ctggttgcgg ccccgcttga caaaaaactg cgtatcaaat gcagataatg
    22561 caattattgc ctaagtggac tattagaaag tcaaggtgtt caggcgttta tttgtaaagt
    22621 tttgttgaaa taagggttgt aattgtgatc acacccgcac ataacccaca gggtgttgtc
    22681 tatactttac acataaggaa gaggggtatt ccctgttaca acccagaaag ttccggaggt
    22741 gacatatgaa acgcaaaaac gcttcgttac tcggtaacgt gctcatgggg ttgggtctgg
    22801 tggtaatggt ggtcggcgtg gggtattcaa tcctcaacca gttaccacag tttaatatgc
    22861 cccagtattt cgcacatggt gctgtgctaa gtattttcgt cggtgcgatt ctctggctgg
    22921 cgggtgcccg tgttggcggg catgaacagg tgtgcgaccg ttactggtgg gttcgccact
    22981 atgacaaacg ttgccgccgt agcgataatc gccgtcatag ctaacaaata atgcagtttg
    23041 ctgaccagtc agtttgcgct gactggtcaa tctcgtactt ataaatccgc catcgccgcg
    23101 cgacgattcg ggaagaatgc gaggcgtccc gggatcggtt gaatgcctgc gcgagccata
    23161 gtgcgcagtg gctggaattc caggttgcac acgcgcagtt cacatccttc gggcagacgc
    23221 ttcacaaaac gctggaacgc atcaagacca ccagcatcaa gtaccggaac ggcatcccac
    23281 ttcagaatca caatccgttt gccttcaaga cgtgactcca ggtccgtgaa taagccttca
    23341 gcggcagcaa aaaacagcgg gccaataacg cgcagaacca ggacatcgtc tggaacgtct
    23401 acgactaccg gtgccaggcg agtcatacgt gcgatacgac gcataaacag cagcgatgcc
    23461 agcacgatcc ccacgctgat ggcaataacc atatcgaaca gcacggtcag cgacatgcac
    23521 agcagcatga cgatgatgtc atctttcggt gcatgacgca gcaagtcgac cactttgtgc
    23581 gcttcactca tgttccacgc caccatcaac agcagggctg ccatggcgga aagtggcagc
    23641 caggagagca gcggtgccag taccagcagg gcaagaataa ccagaataga gtggatcacc
    23701 gccgagatag gggaagttgc cccggcacgg acgttagcgg cagaacgcgc gatggcagct
    23761 gtagcggtaa tgccaccaaa gaacggagcg ataatattcc ccagtccctg tccaaccagt
    23821 tcgctgttcg ccttgtgttt cgtcccggtc ataccatcca gcaccacggc gcagagcaga
    23881 gattcgattg cgccgagcat tgccattgag aatgccgcag gcagcagtgt gcgaatagaa
    23941 tcccaggtta gcgtgaattc tgaattaggc agatcccacg gcagcaccag ttgcggcagc
    24001 agttgcggaa taccgttacc ctgagaacca tcggccagga cgtagtggaa ttgcgaaccg
    24061 atggtagcaa catgtccgcc gagcaggtta acaatcccca tcaccacgca accagccagc
    24121 aaggccggaa ggtggccggg taaacgtatg cccagacgcg gccagaaaac cagaatgcca
    24181 agcgtcacaa tgccaatggc tgcatcaccc acattaatgg tcggcagcgc cataaataat
    24241 gcgccgactt tttgtagata atgttccggg acatgggcca tttgcagacc gagaaaatct
    24301 ttaatctgca tggtaccgat ggtgatcccg atacccgagg tgaaacctaa ggtgacggaa
    24361 accggaatat actcaatcag gcgaccaaag cgtgccagcc ccatcagaat caaaaagatc
    24421 cccgacagca aggtcgcaac cagcagtcct gccagtccaa actgttgcga aacgggatag
    24481 agaattacca caaatgccgc agtcggaccg gaaacgctaa agcgtgaccc tcccgtcaga
    24541 gcaatgacaa tccccgcaac agctgcggta tataaaccgt actggggtgc cacaccacta
    24601 ccaatagcca acgccatcgc cagcgggata gcaataatcc cgacggttat cccggcaatc
    24661 aggtcacggg taaaccgtgc ggcagtatat ttttctttcc agcaagcgtc gatcagagcg
    24721 cggaaaggca tcacatgtga ggaaaatatt ttgttcacaa taatgtttca tccgtgagcg
    24781 catcatctgt caactaaatg gcaggtgaag gaggcatagg tcatacaaat ggatattaca
    24841 gacaaaaaaa cccgccgcag cgggtctttg agccgggttc gattagtgtt cgaacatggc
    24901 agatatcgat tcttcgttgc tgatacgacg aatcgcttcg gccagcatac ctgacagggt
    24961 cagagtacgc acgttcggca gtgatttgat ttcatcgctc agcggaatgg tatcgcagac
    25021 aacgacttca tcaattacag agttacgcag gttgttcgcc gcgttgccag agaagatcgg
    25081 gtgagtcgcg tacgcaaata cacgtttagc accacgttct ttcagagctt cagcagcttt
    25141 acacagcgta ccgccagtgt cgatcatatc atcgaccagt acgcagtcac gacctgcaac
    25201 gtcaccgatg atatgcatca cctgggaaac gttcgcacgc ggacgacgtt tgtcgatgat
    25261 tgccatatcg gtatcgttca gcagcttagc gatagcgcgg gcacgcacaa cgccgccgat
    25321 gtccggagaa accacaattg ggttatccag attcagctgc agcatgtctt ccagcaggat
    25381 cgggctacca aatacgttat caaccggaac gtcgaagaaa ccctgaatct gttcagcgtg
    25441 cagatccact gtcagcacac ggtcaacacc gacgctggag aggaagtctg caaccacttt
    25501 cgcagtgatt ggtacacgag cggaacggac gcgacggtcc tggcgcgcat agccaaagta
    25561 ggggataaca gcggtgatac gacctgcgga agcacgacgc agggcatcaa ccataacgac
    25621 taattccatc aggttgtcgt tagtaggggc acaagtggac tggatgatga aaatatcacc
    25681 accgcgtaca ttttcattaa tttgtacact gacttcgccg tcgctaaagc gacctacagc
    25741 ggcgtcgccg agtgaagtgt acaggcggtt ggcaatacgt tgtgctagtt ccggggtggc
    25801 gttaccagca aaaagcttca tatcaggcac gagaagaacc tcaggcatgc gtccattggt
    25861 ggaaagaatc tgccgaaaac tgtgcgggcc aggcatgatt ctttccaggc ggtgtattaa
    25921 agagcgcgat gcaacgtctg gaacaaggtg acgttgtcac cgaaactcag cttgcccggc
    25981 ttaaagcatg gctctgtgca atggggaaag attaacgcct ttcgccacaa agccattgag
    26041 ccattccggg gcttgctcta gcacctggcg ggcttcagac tctgtatcaa attcagcaaa
    26101 gacacaggcc cctgtcccag tcaggcgcga cggggcgtat tctaacagcc aggaaagcac
    26161 cgcatcaacc tcgcgaaaac gttttcttgc gataacctcg caatcattgc tgaattcaca
    26221 ttttagcaac gtttctattg acctttttgg cgtattgcgc gggagttcag gatctttaaa
    26281 aatcaccggt gtcggaatac ttacaccagg gtgcgccacc agataccact tctctggcgg
    26341 atccaccggc gttagtattt caccaacgcc ttcggcaaac gcggcatgac cacgaacaaa
    26401 gacaggaaca tctgcgccca gcgtcagccc catttccgcc agctcatcca tgcttagtcc
    26461 gcattgccag agatgattta acgccaccag aaccgtcgcg gcattggatg aaccaccgcc
    26521 gagaccgccg cccatcggca aacgcttgtc aatgctgata ttcgcaccgc ttcccgtcga
    26581 aagacgcccg ctgtctgccg cagttttcat caacaaccgc gctgcgcgaa cgatcaggtt
    26641 atcttcatgt tccacgcctt caacgggcgt taacagacga atatccccat cgtcacgaag
    26701 ctcaatgctg atgatgtcgc cgtaatcaag aaactgaaac agcgtttgca gcgtgtggta
    26761 accatccgca cgctgaccgg taatgtataa aaacagatta agttttgccg gagagggcca
    26821 ctgtgtccgc attatttcac tatccagtta tccattttta acttgatgcg ttgaccaccg
    26881 tcggtgagtt ccatattggc tggcatcgca ggttgagttt ttgtgtcata accaccgtaa
    26941 acaactttcc agtttttgcc attctggctg taggtgattt cgctcaggcg gtactggtcg
    27001 tccagtttgt aatcggtcgc atcacccggt aaacctaaaa tccactggcg caagctgttg
    27061 agcggaatcg gcattccggt tagtttacca atcatctctt cggcgtcatc ggcggtgtaa
    27121 cgctgacctt tattgtcgac taattgtacg ttacccggct gagcattcag ctccagttcc
    27181 gtgctgccca atgggttagt taacagcaga cgatagcgat cctggccggt ttgttgccag
    27241 aagaagcgag cgtacacttt ttgttggtcg gaaatataag cgaatgcacc gcgagtctga
    27301 tactgattaa gattacgcac gtcttgctgg tgctgacgcc actgtggcga atccgggctt
    27361 ttgcctgggc ctttgggtgt ggtaacagaa caggcagtga gcacgagggc agctagcggt
    27421 agcaggcgga taaagcgaaa atcgggcagg gtcataataa tgacaagtcc ttgagatacg
    27481 ttgcagttat aacccttaat gctagcgtta ccgttagcca tcgtctatgt tcacgttgtc
    27541 ttaattgcca gaatctaacg gctttcggca attactccaa aagggggcgc tctcttttat
    27601 tgatcttacg catcctgtat gatgcaagca gactaaccct atcaacgttg gtattatttc
    27661 ccgcagacat gaccctttta gcactcggta tcaaccataa aacggcacct gtatcgctgc
    27721 gagaacgtgt atcgttttcg ccggataagc tcgatcaggc gcttgacagt ctgctcgcgc
    27781 agccgatggt gcagggcggc gtggtgctgt cgacgtgtaa ccgcacagaa ctttatctca
    27841 gcgttgaaga acgggatgac ctgcaagagg cgctcattcg ctggttgtgt gattaccata
    27901 atctcaacga agacgatctg cgtaatagcc tctactggca tcaggataac gatgcggtca
    27961 gtcatttaat gcgcgttgcc agtgggcttg attctctcgt ccttggcgag ccgcagatcc
    28021 tcggtcaggt taaaaaagcg tttgccgatt cgcaaaaagg tcatatgaag gccagcgaac
    28081 tagaacgcat gtttcagaaa tctttctctg tggcgaaacg cgttcgcact gaaacagata
    28141 tcggtgccag tgctgtgtct gtcgcttttg cggcttgtac gctggcgcgg cagatctttg
    28201 aatcgctctc tacggtgaca gtactgctgg tgggtgcggg cgaaaccatc gagctggtgg
    28261 cgcgtcatct gcgcgaacac aaagtacaga agatgattat cgccaaccgc actcgcgaac
    28321 gtgcccaaat tctggcagat gaagtcggcg cggaaattat tgccctgagt gatatcgacg
    28381 aacgtctgcg cgaagccgat atcatcatca gttccaccgc cagcccgtta ccgattatcg
    28441 ggaaaggcat ggtggagcgc gcattaaaaa gccgtcgcaa ccaaccaatg ctgttggtgg
    28501 atattgctgt tccgcgcgat gttgagccgg aagttggcaa actggcgaat gcttatcttt
    28561 atagcgtgga cgatctgcaa agcatcattt cgcacaacct ggcgcagcgt aaagccgcag
    28621 cggttgaggc ggaaactatt gtcgctcagg aaaccagcga atttatggcg tggctgcgtg
    28681 cacaaagcgc cagcgaaact attcgcgagt atcgcagcca ggcagagcac gttcgcgatg
    28741 agttaaccgc caaagcgtta gcggcccttg agcagggcgg cgacgcacaa gccattatgc
    28801 aggatctggc atggaaactg actaaccgct tgatccatgc gccaacaaaa tcacttcaac
    28861 aggccgcccg tgacggggat aacgaacgcc tgaatattct gcgcgacagc ctcgggctgg
    28921 agtagcagta catcattttc tttttttaca gggtgcattt acgcctatga agccttctat
    28981 cgttgccaaa ctggaagccc tgcatgaacg ccatgaagaa gttcaggcgt tgctgggtga
    29041 cgcgcaaact atcgccgacc aggaacgttt tcgcgcatta tcacgcgaat atgcgcagtt
    29101 aagtgatgtt tcgcgctgtt ttaccgactg gcaacaggtt caggaagata tcgaaaccgc
    29161 acagatgatg cttgacgatc ctgaaatgcg tgagatggcg caggatgaac tgcgcgaagc
    29221 taaagaaaaa agcgagcaac tggaacagca attacaggtt ctgttactac caaaagatcc
    29281 tgatgacgaa cgtaacgcct tcctcgaagt ccgtgccgga accggcggcg acgaagcggc
    29341 gctgttcgct ggcgatctgt tccgtatgta cagccgttac gccgaagccc gccgctggcg
    29401 tgtagaaatc atgagcgcca gcgagggtga acatggtggt tataaagaga tcatcgccaa
    29461 aattagcggt gatggtgtat atggtcgttt gaaattcgaa tctggcggtc atcgcgtgca
    29521 gcgtgttcct gctacggaat cgcagggtcg tattcatact tctgcttgta ccgttgcggt
    29581 aatgccagaa ctgcctgatg cagaactgcc ggacatcaac ccagcagatt tgcgcataga
    29641 tactttccgc tcgtcagggg cgggtggtca gcacgttaac accaccgatt cggcaattcg
    29701 tattactcac ttgccgaccg ggattgttgt tgaatgtcag gacgaacgtt cacaacataa
    29761 aaacaaagct aaagcacttt ctgtactcgg tgctcgcatc cacgctgctg aaatggcaaa
    29821 acggcaacag gccgaagcgt ctacccgtcg taacctgctg gggagtggcg atcgcagcga
    29881 ccgtaaccgt acttacaact tcccgcaggg gcgcgttacc gatcaccgca tcaacctgac
    29941 gctctaccgc ctggatgaag tgatggaagg taagctggat atgctgattg aaccgattat
    30001 ccaggaacat caggccgacc aactggcggc gttgtccgag caggaataat ggaatatcaa
    30061 cactggttac gtgaagcaat aagccaactt caggcgagcg aaagcccgcg gcgtgatgct
    30121 gaaatcctgc tggagcatgt taccggcaaa gggcgtactt ttattctcgc ctttggtgaa
    30181 acgcagctga ctgacgaaca atgtcagcaa cttgatgcgc tactgacgcg tcgtcgcgat
    30241 ggtgaaccca ttgctcattt aaccggggtg cgagaattct ggtcgttgcc gttatttgtt
    30301 tcgccagcga ccttaattcc gcgcccggat acggagtgtc tggtggagca ggcactggcg
    30361 cggttgcctg aacaaccttg ccgtattctc gatctcggaa cgggtaccgg ggcgattgcg
    30421 cttgcgcttg ccagcgagcg cccggactgc gaaattatcg ctgtagatcg tatgcccgat
    30481 gctgtcgccc tggcacaacg taatgcccag catctggcta tcaaaaatat ccacattctg
    30541 caaagcgact ggtttagcgc gctagccggg cagcagtttg cgatgattgt cagcaatccg
    30601 ccgtatattg acgagcagga cccacatctt caacaaggcg atgtccgctt tgagccgctc
    30661 actgcgctgg ttgcggcaga cagtggaatg gcagacatcg tgcatatcat cgaacagtcg
    30721 cgtaacgcgc tggtatccgg cggctttctg cttctggagc atggctggca gcagggtgaa
    30781 gcggtgcgac aggcatttat cctcgcgggg tatcatgacg tcgaaacctg ccgtgactat
    30841 ggggataacg agcgcgtaac gctcggccgc tattatcaat gacaagtttt tctacgttgc
    30901 ttagcgttca tctcattagt atcgcgcttt ctgttgggct attgacctta cgtttctggc
    30961 tacgttatca gaagcatcca caggcatttg ctcgctggac gcgcattgtg ccgccggttg
    31021 tcgatacgct gttattgtta agcggcattg cgttgatggc taaagcgcac atccagccat
    31081 tttccgggca ggcacagtgg ctgactgaaa agctgtttgg agttatcatt tatatcgttt
    31141 tgggttttat tgcactcgat tatcgtcgga tgcacagtca gcaggcgcgc attattgcct
    31201 tcccgctggc gttggtggtg ctgtacatca tcattaaact cgccaccaca aaagtaccgt
    31261 tactggggta agtcatgaga tcgttagctg atttcgaatt taataaagcg ccattgtgcg
    31321 aaggcatgat cctggcttgc gaagcaatcc gccgcgattt tccctcgcaa gatgtttacg
    31381 acgaactgga gcgtctcgtt agtctggcga aggaagaaat tagccagctt ctgcctttag
    31441 aagagcagtt ggaaaaactg atcgcgctgt tttacggcga ctggggattt aaagcctcac
    31501 gcggcgttta tcgtctttcc gatgcattat ggctggacca ggtgttaaag aatcgacagg
    31561 gcagtgcggt atcattaggt gcggttttat tatgggtcgc gaatcgtctc gatttgccgc
    31621 tgctgccggt gattttccct acgcagctga tattgcgcat tgaatgtccg gatggcgaaa
    31681 tttggctgat taatcctttt aacggtgaat cgttaagcga acatatgctg gatgtgtggt
    31741 taaagggaaa tatcagcccg tcggcggaac tgttttatga agaccttgat gaagctgata
    31801 acattgaggt aatccgcaaa ttgctggata cactcaaagc ttcgttgatg gaagaaaatc
    31861 agatggagct ggcgttacgc accagcgaag ctttattaca attcaacccg gaagatccct
    31921 atgaaattcg cgatcgcggg ttgatttatg cgcaactgga ttgcgaacac gttgcgttga
    31981 acgatttaag ttatttcgtt gaacagtgtc cggaagaccc gatcagcgaa atgatccgtg
    32041 cgcaaataaa taacatcgcg cataaacata ttgtgctgca ttaattaatc gacattttac
    32101 tcaagattaa ggcgatccta tgaaacaaaa agtggttagc attggtgaca tcaacgtagc
    32161 aaatgacctg ccgttcgtac tgtttggcgg tatgaacgtg ctggaatctc gcgatctggc
    32221 gatgcgcatt tgcgagcact acgtaaccgt gacccagaaa ctgggtatcc cttacgtgtt
    32281 caaagcctct tttgacaaag ccaaccgctc ctccatccac tcttatcgtg gaccgggcct
    32341 ggaagaaggg atgaaaatct tccaggagtt gaagcagact tttggcgtga aaattatcac
    32401 cgacgttcac gaaccaagtc aggcacagcc cgttgctgat gtcgtggatg tgattcagtt
    32461 gccggcgttt cttgctcgcc agactgacct ggttgaagcc atggcgaaaa ccggtgcggt
    32521 aattaacgtc aagaaaccac agtttgtcag cccgggacag atgggtaata tcgttgataa
    32581 attcaaagaa ggcggcaacg aaaaagtgat tctttgcgat cgcggtgcta acttcggcta
    32641 tgacaacctg gttgtcgata tgctgggctt cagcatcatg aagaaagtgt ctggtaattc
    32701 gccggtgatt ttcgacgtta cccacgcact gcaatgtcgc gatccatttg gcgcagcttc
    32761 cggcggtcgc cgtgctcagg tggctgagct ggcaagagcc ggtatggcgg taggtctggc
    32821 ggggctgttt attgaagcgc atccggatcc ggaacatgcg aaatgtgatg gtccatccgc
    32881 gctgccgctg gctaaactgg aaccgttcct caagcaaatg aaagcgattg atgatctggt
    32941 gaaaggtttc gaagaactgg ataccagcaa gtaatctttt ttgcctgaaa aataaagtct
    33001 tagcgttctg cgttaagact tttttcatgg gtgccggata caaaaaaggc cgcaggctgt
    33061 tacccctgcg gccggtttcg ggcgcatatt gccatcacgg cagcctgacg cccgttttca
    33121 ccttacttcc ggttacgcca ccagctgaca atcactgcgg taataatccc cgccaggatc
    33181 ggtgccgcca ggttgtgcca gaaaatcatg gcaaactgcg cgagcgtcat atagccgcct
    33241 tgttgtaatg acaacatttt gcggctattc ttgaattgtt ctggttcaag attagccccc
    33301 gttctgttgt caggttgtac ctctcaacgt gcgggggttt tctctttcca gcaaccaatg
    33361 ccaccaggga taaagccccc gcaacattgc gcctcaccgg ataacgccgg cttggtgtgg
    33421 atactacgtc gcaattcatc ttcacttcat ccctgaaatg tttgcaataa agagtacatt
    33481 ccggtttttc aacagctgtt gcagtcattt cgtgcaggtt gtggtacagg cttgcaattc
    33541 tgattaacaa cctgtccagc tagtatgaag aaatataata agcaggaatt tatattatct
    33601 cccccgattt ccgtcatcgg aggagatata actgtcaggc aaatatcgtc atcaaatagg
    33661 cggcaaacag tgccagatgc gctgcgccat tgagcacgtt agttcgtccg gtggagaagg
    33721 agatatggca cagtactaaa gaggccacca tcaccaccat ttctggcgca ccaagtgcaa
    33781 actgcaattc gttacccgtc ataaaggcaa ttagcgtgac gacaggtacg gtaagcgaaa
    33841 tggttgccaa cactgaacca aagaacagat tcatcgcgcg ctggacctgg ttattcaaca
    33901 ctgcttttaa cgcacctaaa ccttccggcg acagaatcaa cagagccacc aggaagccag
    33961 taaaggcgac aggcgcattc atgctgtcga gcaatgtctc cagcgggctg gcgttcattt
    34021 tggtgactgc aataacggca atcagatgga caatcaacca gatggcatgc cacaggctgc
    34081 tatgggcaga cggtttaccg tggtgcgggt cgtcatcatc actgtcatct tcgtgctcgt
    34141 agacaaacaa actttgatgc gttttggtct ggatcagcaa aaatacgcca tacattgccg
    34201 cagaaattaa tgctaccagt aacgcctgac ctgttgaaaa attcgccgca ggcagagcca
    34261 ttggaaatac cagtacgatt atcgccaggg ggaacagcgc aattaaatac tgcttgatac
    34321 caaacagatt catatattgg gtggcaaact tacgtccgcc caacaataat gaaaagccaa
    34381 ccagcccacc tgtaacaatc ataatgattg aatagagcgt atcacgcatt agcgttggcg
    34441 cggcatcgcc ggttgccatt aaagctgaaa tcaaactgac ttcaagaata accactgaaa
    34501 ggctaagaat aagcgaaccg taaggttctc ccaggcgatg ggctaatacg tccgcatgac
    34561 ggacaacact aaaggcgcta cttaaaatac caataagcgc aagaagattg atggcaatga
    34621 ccactggtag tgtctggctg cttccccaca ggaacagcac taccagcgcc agaaccggga
    34681 aaataagcga agtctccttg tggcgggttt ttaccgcctc ttgagcattt gacattatgg
    34741 ttatcccttt gcagatgaat ttatcgaaaa tgtaaaaaat aggtaggaaa aataacagaa
    34801 attgtctgga tatcggtaac attttacgaa tttttacccc gctgtcggtt ttttact
//
LOCUS       DAPOXO010000051        34513 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.051, whole genome shotgun sequence.
ACCESSION   DAPOXO010000051 DAPOXO010000000
VERSION     DAPOXO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34513
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.051"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(12..737)
                     /gene="phoU"
                     /locus_tag="ROH59_002909"
     CDS             complement(12..737)
                     /gene="phoU"
                     /locus_tag="ROH59_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDX4805365.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAEKDSDK"
     gene            complement(752..1525)
                     /gene="pstB"
                     /locus_tag="ROH59_002910"
     CDS             complement(752..1525)
                     /gene="pstB"
                     /locus_tag="ROH59_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HDX4805366.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(1616..2506)
                     /gene="pstA"
                     /locus_tag="ROH59_002911"
     CDS             complement(1616..2506)
                     /gene="pstA"
                     /locus_tag="ROH59_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDX4805367.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMIASITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(2506..3465)
                     /gene="pstC"
                     /locus_tag="ROH59_002912"
     CDS             complement(2506..3465)
                     /gene="pstC"
                     /locus_tag="ROH59_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HDX4805368.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(3551..4591)
                     /gene="pstS"
                     /locus_tag="ROH59_002913"
     CDS             complement(3551..4591)
                     /gene="pstS"
                     /locus_tag="ROH59_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDX4805369.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            complement(4905..6734)
                     /gene="glmS"
                     /locus_tag="ROH59_002914"
     CDS             complement(4905..6734)
                     /gene="glmS"
                     /locus_tag="ROH59_002914"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDX4805370.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(6896..8266)
                     /gene="glmU"
                     /locus_tag="ROH59_002915"
     CDS             complement(6896..8266)
                     /gene="glmU"
                     /locus_tag="ROH59_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDX4805371.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPIKKK"
     gene            complement(8620..9039)
                     /gene="atpC"
                     /locus_tag="ROH59_002916"
     CDS             complement(8620..9039)
                     /gene="atpC"
                     /locus_tag="ROH59_002916"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDX4805372.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(9060..10442)
                     /gene="atpD"
                     /locus_tag="ROH59_002917"
     CDS             complement(9060..10442)
                     /gene="atpD"
                     /locus_tag="ROH59_002917"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDX4805373.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(10469..11332)
                     /gene="atpG"
                     /locus_tag="ROH59_002918"
     CDS             complement(10469..11332)
                     /gene="atpG"
                     /locus_tag="ROH59_002918"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDX4805374.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(11383..12924)
                     /gene="atpA"
                     /locus_tag="ROH59_002919"
     CDS             complement(11383..12924)
                     /gene="atpA"
                     /locus_tag="ROH59_002919"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDX4805375.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(12937..13470)
                     /gene="atpH"
                     /locus_tag="ROH59_002920"
     CDS             complement(12937..13470)
                     /gene="atpH"
                     /locus_tag="ROH59_002920"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDX4805376.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(13485..13955)
                     /gene="atpF"
                     /locus_tag="ROH59_002921"
     CDS             complement(13485..13955)
                     /gene="atpF"
                     /locus_tag="ROH59_002921"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDX4805377.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(14017..14256)
                     /gene="atpE"
                     /locus_tag="ROH59_002922"
     CDS             complement(14017..14256)
                     /gene="atpE"
                     /locus_tag="ROH59_002922"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HDX4805378.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(14303..15118)
                     /gene="atpB"
                     /locus_tag="ROH59_002923"
     CDS             complement(14303..15118)
                     /gene="atpB"
                     /locus_tag="ROH59_002923"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDX4805379.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(15127..15507)
                     /gene="atpI"
                     /locus_tag="ROH59_002924"
     CDS             complement(15127..15507)
                     /gene="atpI"
                     /locus_tag="ROH59_002924"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HDX4805380.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
     gene            complement(16124..16747)
                     /gene="rsmG"
                     /locus_tag="ROH59_002925"
     CDS             complement(16124..16747)
                     /gene="rsmG"
                     /locus_tag="ROH59_002925"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDX4805381.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
     gene            complement(16811..18700)
                     /gene="mnmG"
                     /locus_tag="ROH59_002926"
     CDS             complement(16811..18700)
                     /gene="mnmG"
                     /locus_tag="ROH59_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDX4805382.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(19079..19522)
                     /gene="mioC"
                     /locus_tag="ROH59_002927"
     CDS             complement(19079..19522)
                     /gene="mioC"
                     /locus_tag="ROH59_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HDX4805383.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     SASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKIEAELKNSGAKQTGETLKINILDHNIPEDPAEEWLGSWINLLK"
     gene            complement(19612..20070)
                     /gene="asnC"
                     /locus_tag="ROH59_002928"
     CDS             complement(19612..20070)
                     /gene="asnC"
                     /locus_tag="ROH59_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HDX4805384.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            20222..21214
                     /gene="asnA"
                     /locus_tag="ROH59_002929"
     CDS             20222..21214
                     /gene="asnA"
                     /locus_tag="ROH59_002929"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDX4805385.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSKEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLEL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(21219..22670)
                     /gene="viaA"
                     /locus_tag="ROH59_002930"
     CDS             complement(21219..22670)
                     /gene="viaA"
                     /locus_tag="ROH59_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HDX4805386.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTLVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(22664..24160)
                     /gene="ravA"
                     /locus_tag="ROH59_002931"
     CDS             complement(22664..24160)
                     /gene="ravA"
                     /locus_tag="ROH59_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HDX4805387.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGALVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPASLQITDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC"
     gene            24383..26251
                     /gene="kup"
                     /locus_tag="ROH59_002932"
     CDS             24383..26251
                     /gene="kup"
                     /locus_tag="ROH59_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HDX4805388.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            26418..26837
                     /gene="rbsD"
                     /locus_tag="ROH59_002933"
     CDS             26418..26837
                     /gene="rbsD"
                     /locus_tag="ROH59_002933"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709562.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDX4805389.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAVIIAEEIKQHNPQLHETLLTHLEQLQQHQGNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            26845..28350
                     /gene="rbsA"
                     /locus_tag="ROH59_002934"
     CDS             26845..28350
                     /gene="rbsA"
                     /locus_tag="ROH59_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HDX4805390.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKLQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            28355..29320
                     /gene="rbsC"
                     /locus_tag="ROH59_002935"
     CDS             28355..29320
                     /gene="rbsC"
                     /locus_tag="ROH59_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDX4805391.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            29345..30235
                     /gene="rbsB"
                     /locus_tag="ROH59_002936"
     CDS             29345..30235
                     /gene="rbsB"
                     /locus_tag="ROH59_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HDX4805392.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            30361..31290
                     /gene="rbsK"
                     /locus_tag="ROH59_002937"
     CDS             30361..31290
                     /gene="rbsK"
                     /locus_tag="ROH59_002937"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDX4805393.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDISPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKTLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            31294..32286
                     /gene="rbsR"
                     /locus_tag="ROH59_002938"
     CDS             31294..32286
                     /gene="rbsR"
                     /locus_tag="ROH59_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HDX4805394.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA"
     gene            complement(32252..33679)
                     /gene="mdtD"
                     /locus_tag="ROH59_002939"
                     /pseudo
     CDS             complement(32252..33679)
                     /gene="mdtD"
                     /locus_tag="ROH59_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
     gene            complement(33702..34394)
                     /locus_tag="ROH59_002940"
     CDS             complement(33702..34394)
                     /locus_tag="ROH59_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDX4805395.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMAALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDAIIQSDGDAAF
                     KACQALLRSPDK"
BASE COUNT         8322 a         8923 c         8806 g         8462 t
ORIGIN      
        1 tacttggtga attatttatc gctatctttt tctgccagca gtttatcgag ctcgtcacca
       61 ccgacgtgac ggaaatcctg ccccttcacg tagtagaaga taaactcaca aatattctgg
      121 cagcggtcgc caatacgttc gatagaacgc gcacagaata acgcggtaag tacgctcgga
      181 atggtacgcg aatcttccat catgtaggtc atcagttgac gaacaatacc ttcgtactcc
      241 tgatcgactt ttttatcttc acgataaata cgtaccgctt cgtcaatgtc catccgcgcg
      301 aacgcgtcca gcacgtcgtg cagcatctgg atggtatgac ggcccagcga ctccagactt
      361 accagcaacg gctgatgctg ctgggagaat ttctccagcg cagtacggca gattttatcc
      421 gccacgtcac caatacgctc cagctcggca atggttttac tgattaccat caccagacgc
      481 aggtcgctcg ccgtcggctg acgtttggcg ataatgcgca cgcaggcttc atcgatcgcc
      541 acttccatca tgttgacgtt cttgtcgcct tcgatgacgc gcttcgccag atcgctgtcc
      601 tggttatgca tcgcggtgat tgcatcagaa agctgctgct ccaccatgcc gcccatggtc
      661 atcacctgcg tgcggatgct ttccagttcg gcgttgaact ggccggaaat atgtttatta
      721 agattgagac tgtccataac gcactcctga atcaaccgta acgaccggtg atgtagtctt
      781 ctgtttgttt tttcgctggc ttggtgaaca gatcgtccgt gttgctgaac tcaatcaatt
      841 cgcccaggta cataaacgcc gtgtggtcgg aacaacgcgc agcctgctgc atgttgtggg
      901 tgacgatcac cacggtgtaa tcctgcttca gttcggtgat cagctcttca atacgcccgg
      961 tagagatagg gtcgagtgcc gaacacggtt cgtcgagcag cagcacttcc gggcgaatgg
     1021 cgataccacg cgcaatgcac agacgctgtt gctgaccacc agagagagag taaccgctct
     1081 ggtgcaattt atctttggtt tcgttccaca atgcggcttt ggtcaatgcc cactgcacgc
     1141 gctcgtccat gtcggcacgg gagagcttct caaacagacg cacgccaaag gcgatgttgt
     1201 cgtaaatgga catcgggaac ggcgtcggtt tctggaacac catgcccact ttcgcacgca
     1261 gcagggcgat atcctgagag ttggtcagga tgttgtcgcc atcgagcaga atttcacctt
     1321 ccgcacgctg ctccgggtac agttcaaaca ttttgttgaa ggtacgcagc agcgttgatt
     1381 taccgcagcc ggacggcccg ataaacgccg taacctggtt tttggcgata tccaggttga
     1441 tgtttttcag ggcatggaat ttgccgtagt agaagttcaa attacgaacc tgaattttac
     1501 tcggggcagt ttcaaccata ctcattgcaa tcttttcctc atcgtgcctg atgcacttcg
     1561 cgaatcaggc ttaccgtagg ccggataagg cgtttacgcc gcatccagca aagtgttaac
     1621 cgtgtttatt cttcgcaaaa acaacgcgcg ccagaatgtt cagcagcagt acgcacaggg
     1681 taatgatcaa caccccggcc caggccagtt gctgccattc cgcaaacggg ctcatcgcaa
     1741 acttaaagat cgtcaccggc aggttggcga tcggctgcat catgtccgtg ctccagaact
     1801 ggttggagag cgcagtaaac agcagcggtg cggtttcacc agcaatacgg gcaatcgcca
     1861 gcaggatacc ggtcatgatc ccggacaccg acgctttcag cgtgatcgag gcgatcatct
     1921 tccacttcgg cgtacccagc gcataagccg cttcacgcag gctgtccggc accagtttca
     1981 gcatgttctc ggtggtgcgg ataacaatcg gcacctgcaa cagcgccagc gcaatcacgc
     2041 ccgcccagcc ggagaagtgc tccatctgcg ccaccacgat ggtgtaaaca aaaagaccaa
     2101 ccacaatcga cggcgcggag agcagaatgt cgttaatgaa gcgaatcact tctgccagcc
     2161 aggatttacg accatattca gccaggtaaa tccccgccat aatgcccagc ggcgtaccga
     2221 ataccgtagc ccacaaaatt aacaggccgc tacccgccag ggcgttcgcc agaccaccgc
     2281 cttccgtatt gggtggtggc gtcatttcgg tgaacagcgc cagcgacata ccgtcgatac
     2341 cgcgagtgat ggtggacatt aaaatccaga tcagccagaa cagaccgaag gccatcgtcg
     2401 ccattgagag cgtcagcgca atacggtttt tgaggcggcg acgcgcctgc attttgcggc
     2461 gggattcagc cagtgccgca gtggtttgca tttcaaccat agccattagc gtgccccctc
     2521 attcttagcc aggcgcataa tcataaactt cgatgcggcg aggacgatga aggtaatcac
     2581 aaacaggatc aggcccagtt ccatcagtgc agcaacgtgc agacccgact ctgcttcggc
     2641 aaattcgttc gccagcgcag aggtgatact gttgcccggc atgtacagcg aggcgctgtc
     2701 gagctggtag gtgttaccga tgataaaggt caccgccatg gtttcaccaa gcgcgcggcc
     2761 cagccccaac ataatgccgc cgataacacc atttttggtg aacggaagaa cgatacgcca
     2821 gataacttcc caggtggtgc agccaatacc gtaggccgac tctttcatca tcaccggggt
     2881 ttgttcgaac acatcgcgca ttaccgccgc aatgtacgga ataatcatga tggcgaggat
     2941 cacgcctgcc gcgaggatac cgataccaaa ggccgggccg gagaacagcg cgccgacaat
     3001 cgggatattc gacatgatat tgccgaccgg ctcctggaag taaacggcga acagcggcgc
     3061 aaagataaac aggccccaca tgccgtaaac gatacttgga atggctgcca gcagctcaat
     3121 ggcgataccc agcgggcgct tcagccagcc aggcgcaagc tcggtcagga acagggcgat
     3181 accgaaactc accgggacgg cgatcagcag cgcgataaac gaggtcacca gcgtaccgta
     3241 gatcggcacc agcgccccgt agatatcgtt cggcgcatcc cactctttgg tccacaggaa
     3301 agccagacca aatttctgaa tgctcggcca ggaggagatg atcagagaga caataatgcc
     3361 acccaacatc aatagcacaa tcagcgccgc cagttttacc agcacgctga aaattatgtc
     3421 gcccttttta cccggtgggt taaaagcagg cttggttgca gccataagtt actcttcagt
     3481 taaacgcgtt tacaaagtca ttttgtaatg ccggatgcgg cgtaaaacac cgtacccggc
     3541 ctgagtttta ttagtacagc ggcttgccgc tactgtcttt aatattggtc ttccacgcag
     3601 cgcgaacctg ttccactacg ctatccggca ggctggcgta atccaggtcg ttcgcctgtt
     3661 tagccccggt tttgtatgcc cagtcgaaga acttcagcac ttctgtgcct tgttctggtt
     3721 tcttctgatc tttgtggatc agaatgaacg tggtagaggt aataggccac gcatcttcgc
     3781 ctttctggtt ggtcagatcc tgagcgaatg ttttgctcca gtctgcgcct tttgctgcat
     3841 tagcgaagtt ttcttcggtc ggactaaccg gtttgccatc agcggagatc aatttggtgt
     3901 acgccaggtt gttctgcttc gcgtaagcat attcaacgta accaattgca cccggcagac
     3961 gctgaacgaa cgcggcgata ccgtcgttac ctttaccgcc cagaccgatc ggccatttta
     4021 cggtagagcc agtaccaacg ttgtttttcc actcttcgtt cactttcgcc aggtagctgg
     4081 tgaagacgaa ggaagtcccg gagccatctg cgcggcgtac tacagcaatg ttctgtgaag
     4141 gcagtttcag acccggattc agtttggcga tggcttcatc atcccacttc ttgattttgc
     4201 ccaggtagat gtcgccgagg gttttaccat ccagcaccag ttcgccagac ttcagacctg
     4261 gaatattaac cgccagcacc acgccgccaa tcacggtcgg gaactggaac aggccttcct
     4321 gagccagttt ttcatcagac agcggcgcgt cagaggcacc gaaatcaacg gtgttagcga
     4381 taatctgttt tacgccaccg gaagaaccga taccctggta gttaacttta ttaccggttt
     4441 ctttctggta agtgtcagcc catttggcat acaccggcgc agggaaggtt gcacctgcac
     4501 ctgtcaggct tgcttctgca aacacagaga aagcactcat cgataaggtc gcggcgacaa
     4561 cagttgcgac ggtggtacgc ataactttca taatgtctcc tgggaggatt cataaagcat
     4621 tgtttgttgg ctacgagaag caaaatagga caaacaggtg acagttatat gtaaggttta
     4681 tgacagtttt atgacagaga gagaaagtct ttagtctgat ttaaataagc gttgatattc
     4741 agttaattac aaatattaat aacgaagaga tgacagaaaa attttcattc tgtgtcagag
     4801 aaaaagtagc cgaagatgac ggtttgtcac atggagttgg caggatattt gattaaaaac
     4861 ataacaggaa gaaaaatgcc ctgcttacgc agggcatcca tttattactc aaccgtaacc
     4921 gatttcgcca ggttacgcgg ctggtcaacg tcggtgcctt tgatcagcgc aacgtggtaa
     4981 gccagtagtt gcagcggaac ggtgtagaag atcggtgcaa tcacctcttc cacatgcggc
     5041 atctcaatga tgtgcatgtt gtcactgctc acaaaacccg catcctgatc ggcgaagaca
     5101 tacaactgac cgccacgcgc gcgaacttct tcaatgttgg atttcagttt ttccagcaat
     5161 tcgttgttcg gtgcaacgac gataaccggc atatcggcat caatcagcgc cagcggaccg
     5221 tgtttcagtt cgcctgcagc gtaggcttca gcgtgaatgt aagagatctc tttcagcttc
     5281 aatgcacctt ccagcgcgat tgggtactga tcgccacggc ccaggaacag cgcgtgatgt
     5341 ttgtcagaga aatcttctgc cagcgcttca atgcgtttgt cctgagacag catctgctca
     5401 atacggctcg gcagcgcctg cagaccatgc acgatgtcat gttcaatgga ggcatccaga
     5461 cctttcaggc gagacagttt cgccaccagc atcaacagca cagttaactg ggtggtgaat
     5521 gctttggtgg aggccacgcc aatttccgta ccggcgttgg tcatcagcgc cagatcggat
     5581 tcgcgcacca gagaagaacc cggaacgtta cagattgcca gcgaaccaag gtaacccagc
     5641 tctttcgaaa gacgcaggcc cgccagggta tccgcggttt cgccagactg tgacaaggtg
     5701 atcatcaggc tgttacgacg cacggcagat ttgcgatagc ggaattcaga ggcgatttcg
     5761 acgtcgcacg gaatacctgc cagcgattca aaccagtagc gggaaaccat accggagtta
     5821 taagaagtac cacaggcgag gatctgaata tgctcaacct tcgacagcag ttcatcggcg
     5881 ttcggtccca gctcgcttaa atcaacctga ccgtggctga tgcgcccggt aagggtgttt
     5941 ttgatcgcgt tcggctgttc gtagatctct ttctgcatgt agtggcggta aataccttta
     6001 tcgcccgcgt catattgcag attggattcg atatcctgac gttttacttc cgcgccagtt
     6061 ttatcgaaga tgtttaccga acggcgagtg atttccgcaa tatcgccctc ttcaaggaag
     6121 ataaaacgac gagtcactgg caacagcgcc agctggtcag aagcgataaa gttttcgccc
     6181 atacccaggc caatcaccag cggactacca gaacgtgccg ccagcagggt atccggatga
     6241 cgggagtcca tgatcactgt accgtacgca ccacgcagtt gcgggatagc acgcagaact
     6301 gcctcacgca gagtaccgcc ttgtttcagc tcccagttca ccaaatgtgc aatcacttcg
     6361 gtgtcggttt cagaaacgaa ggtatagcca cgcgctttta actcttcacg cagcggttca
     6421 tggttttcga tgatgccgtt atgcaccacc acaatgtgtt cagaaacatg cggatgcgcg
     6481 ttagcttctg aaggttcacc gtgggtcgcc cagcgagtgt gagcaatacc ggtgccgcca
     6541 tgcagaggat gttcttccgc tgcctgagcc agcatctgta ctttaccgag gcgacgcagg
     6601 cgggtcatat gaccttcagc atccaccacg gccaggccgg cagagtcata tccgcgatat
     6661 tccagacgac gtaaaccttc aagaaggatt tctgctacat cacgttgcgc gatcgcgcca
     6721 acaattccac acatagtttt tgattccgat ttatatcgtt gtcggtcaac ctgtatgccc
     6781 gttttttcgg gcgccccgag ccttgtagag agtggggtta tttttatagt tactgcttgt
     6841 gggcgggaga ttatgttatc tcctcatccc atatgaccgg attacccgac cagaattact
     6901 ttttctttat cggacgacgc cagccttctt tttgagtctg cggcacacgg ctgatagcca
     6961 gggcattttc gccgacatta cgcgtcacag ttgtacccgc agcaatggtc gcgcctttgc
     7021 ctactgttac cggggccacc agttgagtgt cggaaccgac aaacacatcg tcgccgataa
     7081 tggtcttaaa tttattcgca ccatcgtagt tgcaggtaat ggttcccgca ccgatgttaa
     7141 cgttatcgcc aatttccgca tcgcccaggt aagtcagatg accagctttc gagcctttac
     7201 ccagacgcgc ttttttcatc tcaacgaagt taccgacgtg tgcaccttcc agcaactcag
     7261 caccaggacg cagacgggca aacgggccaa tagtacaggc cgctgccaga ttcgcatctt
     7321 ccacgacggt atatggactg atttcgcaat catcgccaat cacgctgttt ttaatcacgc
     7381 aaccggtgcc gattttcacg cgatgaccga gagtcacgtt gccctcgatg ataacgttag
     7441 tatcaatttc aacatcgcgc ccgtgagtaa gcgtaccgcg cagatcaaaa cgcgccggat
     7501 cgcgcagcat aacgcctgct aacagcagtt tttcagcctg ttcggactgg taaacgcgct
     7561 ccagtcggga gagttgcagg cggttattca cgccttctac ttcgcttaaa cgttgcggat
     7621 gaacggcgac gatttcacgt ccttcctgat acgccagcgc aataatgtcg gtgatgtagt
     7681 attcgccctg agcattattg ttggtcagct tcgccagcca gcgtttcata tctgcgccgt
     7741 tggcaatcag aatgccggtg ttgatctcct gaatctgacg ctgctcgtcg gtggcatctt
     7801 tgtgttcaac aatgccggta actttgccgt tttcacgggt gatacgtcca taaccggtcg
     7861 gatcatccag ttttaccgtc agcagaccaa tgccaccctg cggtttagca tcacgcagac
     7921 gctggagtgt ttcgacagag atcagcggca cgtcgccgta gagcattaaa atgtcttcat
     7981 catcggcaaa gaaaggtgcg gcctgctgca tcgcatgacc cgtacccagc tgttctgcct
     8041 gaagcaccca gttcaggttg tcgtctttca gcgcctgctt aagcagatcg ccgccgtgac
     8101 catacacaag gtgaacgtgc gctgcgccta attcattcgc agcatcaatg acatgctgaa
     8161 ccatcgcttt cccggcaagg gtatgcagca ctttcggaag atcggaatac atgcgcgtgc
     8221 ctttgcctgc ggcaaggatc actacgctca tagcattatt caacatacgc gtcctgactg
     8281 taatttgaga acgaatttaa accgcttcac cttgaaaaaa ctacattttt ttcatcgtga
     8341 aatggacaga ggataaattg ttcaataacg gattatcccc gctgacgaaa gcgccatttt
     8401 cgaccatcgt cacgcctttt gtctgcagaa aattaaggca gtaccttcat ttaagcgtca
     8461 ggtggatgtt tttgctctta tttcgatcaa tgaataaacg ggaaaacagg ggtgttttat
     8521 atcatcagga tctatgtgaa cgcttttcag gacgggtcaa tacgcgtaaa aaaaagccag
     8581 cctgttgcca gactggcttt tgtgcttttc aagccggtgt tacatcgctt ttttggtcaa
     8641 ctcgataacg cgcagctgcg cgatcgcttt ggccagttcc gcagacgcct gagcgtaatc
     8701 tacgtcgccg tgagagctgc taatgtgctc ttcagcctta cgtttcgctt ccatggctcg
     8761 cgcttcgtcg agatcctggc cgcgaattgc ggtgtcggcc agaacggtca cgttgccagg
     8821 ctgcacttca agaatgccgc cagacagata gataaactct tcgtgaccgt gctgtttcac
     8881 gatgcgaatc ataccaggct taatggcggt gagcagcggt gcgtggccag ggtagatccc
     8941 cagttcacct tcgctacccg ttacctggat tttctcgacc agaccagaga acatttgttg
     9001 ctctgcgctg acgacgtcca ggtggtaagt cattgccata tcaccctccg attaaggcgt
     9061 taaagttttt tggctttttc cacagcttct tcgatggaac cgaccatgta gaacgcctgc
     9121 tccggcaggt gatcgtattc gccttccatg atgcctttaa agccacggat ggtgtctttc
     9181 agggagacgt atttacccgg agaaccggtg aatacctctg ccacgaagaa cggctgggac
     9241 aggaagcgct ggatcttacg agcacgcgct accaccagtt tgtcttcttc agacagttca
     9301 tccataccca ggatggcgat aatgtctttc agttcctgat aacgttgcag gatggactga
     9361 acgccacgcg cggtgtcgta gtgttcctga ccaaccacca gcgggtccag ctgacggctg
     9421 gtggagtcca gcgggtcaac ggccgggtag atacccagag acgcgatctg acggctcagt
     9481 accacggttg cgtcaaggtg cgcaaaggtg gttgccggag acgggtcagt caggtcatcc
     9541 gcaggtacgt ataccgcctg tacggaggtg atagaaccgg ttttggtgga ggtgatacgt
     9601 tcctgcagaa cgcccatctc ttccgccagg gtcggctgat aacctaccgc tgaaggcata
     9661 cggcccagca gtgcggatac ttccgtaccg gccagggtgt aacgatagat gttgtcaacg
     9721 aacagcagaa cgtcacgacc ttcgtcacgg aatttctcag ccatggtcag accggtcaga
     9781 gcaacgcgca gacggtttcc cggcggctcg ttcatctggc catacaccag ggatactttg
     9841 tcgataacgt tggagtcggt catttcgtgg tagaagtcgt taccctcacg agtacgttca
     9901 cctacgcccg caaacacaga gtaaccggag tgctcgatcg cgatgttacg aataagctcc
     9961 atcatgttta cggttttacc tacacccgca ccaccgaaca gaccaacttt accgccctta
    10021 gcgaacggac acatcaggtc gataactttg ataccggttt ccagcagttc ctgagagttt
    10081 gacagctctt cgtaggaagg tgctgcgcgg tgaatcgccc aacgctcttc ttcaccgatc
    10141 tcgcctttca tgtcgaccgg ttcacccagt acgttcatga tacgacccag agtcgcttta
    10201 cctaccggga cttcgatcgg gtgttcgagg tcttttacat ccagaccgcg acgcagaccg
    10261 tcggaggaac ccattgcgat ggtacgcacg ataccgccgc cgagctgctg ctgaacttcc
    10321 agcaccagac gctcattacc attttgcacc tcaagagcat cgtacacgcg cggtacggca
    10381 tcctgaggga attcgacgtc aactacggcg ccgattacct ggacaatctt tccagtagcc
    10441 atcttaaatc ctctacgaaa taacctgttt aaaccgcggc ggcccccgag acgatctcgg
    10501 tgagttcctg agtaatgctg gcctgacgag ctttgttgta taccaactgc agctctttaa
    10561 tcaggctgcc gccattgtcg gtcgcggctt tcatcgccac catacgggcg gcctgctcgc
    10621 tggccaggtt ttcaaccacg ccctgataaa cctgagattc gacataacga cgcagcaggg
    10681 tatccagcaa cgccttcgga tcgggttcgt acaggtaatc ccaggattta tgtttcagat
    10741 catcatcatc tgatgccggt aacggcagca gctggctgat ggtcggaacc tgagacatgg
    10801 tgttaataaa tttgttgctg acaatgtaaa gcttgtccag acggccttcg tcgtaggcct
    10861 gcaacatcac ttttaccgga ccgatcagtt cggacaagga agggttatcc cccatgccgg
    10921 tgacctgggc aacaacattg ccgcccacgg agttgaagaa cgacacgcct ttcgagccga
    10981 tcattgcgag gtcgcattga acgcctttgt cggtccaggt cttcatttcc gccagcagtt
    11041 ttttgaacag gttaatgttc aaaccaccgc acaaaccacg gtcggtcgac accaccaggt
    11101 agcccacgcg tttaacgtcg cggtcttcca ggtaagggtg cttatattcc agattaccgt
    11161 gtgcaaggtg accaatcact ttgcgcatgg tttctgcata aggacggctg gccgccatgc
    11221 gatcctgcga tttacgcatt ttggaagcgg cgaccatctc cattgcttta gtgatctttt
    11281 gcgtgttctg gacgcttgcg atcttactac gtatctcttt tgcgccggcc atgagcttct
    11341 cctcaatgcc ttgcggcctg cccaaaggca agccgccaga cgttaccagg attgggttgc
    11401 tttgaaggaa tcgaggatgc ctttcagctt gccttcgatt tcgtcgttgt agccaccggt
    11461 ctggttgatc tcttgcatca acggagcgtg atcacggtcg acgtaagcca acagagcggc
    11521 ttcgaagctg ccgattttcg acagttcaac atccgccagg taaccacgtt ctgctgcgaa
    11581 cagaaccaga gactgttgcg caacagacat cggcgcatac tgtttctgct tcagcagttc
    11641 ggtcactttc tgaccgtggt caagctgctt acgtgttgca tcgtcaaggt cggatgcaaa
    11701 ctgagagaac gctgccagtt cacgatactg tgccagagcg gtacggatac caccggacag
    11761 ttttttcatg atcttggtct gtgctgcacc accaacacgg gatacggaaa tacccgggtt
    11821 aaccgcagga cgaataccgg cgttgaacag gttggtttcc aggaagatct gaccatcggt
    11881 aatggagatt acgttggtcg gaacgaacgc agaaacgtca cccgcctgag tttcgataat
    11941 cggcagcgca gtcagagaac cggttttccc tttcacttca cctttggtga aagcttcaac
    12001 gtattcggcg ttaacacgcg cagcacgctc cagcagacga gagtggaggt agaatacgtc
    12061 gcccgggaat gcttcacgtc ctggcggacg acggagcagc agggagatct gacggtaagc
    12121 aacagcctgt ttagacaggt catcgtaaat gatcagcgca tcttcaccgc ggtcacggaa
    12181 gtattcaccc attgcgcaac cagcgtacgg tgccaggtat tgcagtgcag cggattcaga
    12241 cgcggttgct accacaacga tggtgttagc cagtgcgccg tgctcttcca gtttacgtac
    12301 cacgttagaa atggtggacg ctttctggcc gatagcgaca tagatacatt tgataccgga
    12361 atcgcgctgg ttgatgatgg catcgatagc cagtgcggtt ttaccggtct gacggtcacc
    12421 gatgatcaat tcacgctgac cacgaccgat tgggatcatg gagtcaacgg ctttataacc
    12481 ggtctgtacc ggctgatcta cggactgacg ttcgataacg cccggagcga ttgcttctac
    12541 agcagagaag ccgtcgtgat ccagcggacc tttaccatcg attggtgcac ccagagtgtt
    12601 aaccacacgg cccagcaggc cacggccaac cggaacttcc aggatacggc cagtacactt
    12661 aactttcatg ccttcggcaa ggtcagcgta cggccccata acaaccgcac ctacagagtc
    12721 gcgctcgagg ttcagtgcga tagcgtaacg gttacccggc agggagatca tttcaccctg
    12781 catacaatcg gccaggccgt gaatgcggat aacaccgtca cttacagaaa caatagtacc
    12841 ttcgttgtga gcttcactca caacattgaa ctgagcaatg cgctgcttga tcagttcgct
    12901 gatttcggtg gaattcagtt gcatgctcca gtccccttaa gactgcaaga cgtctgcaag
    12961 gcgctcaaga cgaccgcgta cgctgccatc aatgaccata tcacccgctc ggatgataac
    13021 acctgccatt acagacttat cgattttgca attcagctta actttgcgtg acagacgttt
    13081 ttccatcgca gcagaaattt tcgcgagctg ttgttcactc aacgcggcag cggaaatgac
    13141 gtctacctca gcggtagcct cactcacagc acgcaggtga ataaactgct ccagaacatc
    13201 cgggagcgcg ttaagacgac cattttcggc cattacccga atcaggttct gaccgttttc
    13261 gtccagttgc tcaccacaaa ctgcgataaa cgactcggcg agcgtttctg gcgcaagcgc
    13321 gccagagaga agctctgcca tttgttcgtt tttggttacc tcggcggcaa acgccagcat
    13381 gtcctgccag cgttctacac tttggtgttc gacggcaaag tcaaaagctg ctttggcgta
    13441 ggggcgagct accgtaataa attcagacat cagcccctcc ctccttacag ttcagcgaca
    13501 agtttatcca cgatgtcgct gttagcagct tcatccacgg aacgttcgat gatcttctcg
    13561 gcgccagcaa cagccaggat agcaacttgc ttacgcagct cttcacgggc acgtttacgc
    13621 tcggcttcaa tttccgcctg cgcctgggcc acgattttag tacgttcctg ttctgcctca
    13681 gctttcgctt catccagaat ctgcgagcgg cgtttgttag cctgctcgat gattacctgg
    13741 gcttccgctt tcgctttttt cagctggtcg gtcgcgctgg cctttgcaag gtcaaggtcc
    13801 ttatgtgctc gttctgcgga agcaaggccg tcagcaattt ctttttgacg tttttcgatg
    13861 gctgccatta atggcggcca tacgtacttc atgcagaaca gaacgaacag gacaaacgcg
    13921 atggcctggc cgaggattgt tgcgttaaga ttcacagcac aatgcctcta tttagttaac
    13981 gttctgatat tgctctttaa ataaaagcaa cgcttactac gcgacagcga acatcacgta
    14041 cagacccaga cctacagcga tcatcgggat agcatccacc agacccataa cgataaagaa
    14101 ctgagtacgc agcagaggaa tcagatcagg ttgacgcgct gcgccttcca ggaatttacc
    14161 cccgaggatg ccgataccga tcgcagcacc gattgccgcc agacccatca tcacagcggc
    14221 agccatgtac agcagatcca tattcaggtt ttccatgaca gtctccagtt tgtttcagtt
    14281 aaaacgtagt agtgttggta aattaatgtt cttcagacgc catcgacaga tagacgatcg
    14341 tcagaaccat gaagatgaag gcttgcagcg taatgatcag gatgtggaaa atggcccacg
    14401 gcacattcag gatccactgt gaccaccacg gcaacagacc agcaatcaga atgaaaatca
    14461 gctcaccggc atacatgtta ccgaacagtc gcaaaccgag tgaaactggt ttggacagca
    14521 ggcttacccc ttcaaggatt aagttgacag gaatgaacgc ccagtgattg aacggctgca
    14581 gcgtcaactc tttcgtgaag ccgccgatgc ctttcatttt gatgctgtag aacagaatca
    14641 ggataaatac gcccagtgcc atagacagcg ttacgttcac gtcagcagac ggaaccacac
    14701 gcagtgcagg cagacccagt acatgttcag caatgtacgg cagcaggtcg ataggcagta
    14761 aatccatcag gttcatcagg aatacccaga cgaagatcgt cagggccagc ggagcaatca
    14821 gcttgctttt gccatggtac atgtctttca cgctaccatt aacaaagccg atcaccagct
    14881 caatcgcggt ctgaaactta cctggcacgc cgctggttgc ctttttggct acactacgga
    14941 ataaaaccag gaacaacaga cccagcacca ccgagaagaa catggagtca atattgattg
    15001 tccagaaggt ggctgggggg ttatgtggat ccaccagcga gaatgtacgc aggtccagct
    15061 gaaggttatt caggtggtgt cctatgtaat cctgcggcgt catattttct gaagccatga
    15121 tgccttttac cctttgttgt taattacagc cggtgccagt atctgaacca ccagcaccaa
    15181 aacccacgta acgatcagcg gcaagaatac cgcctttaaa accgccaacg ccaccaccag
    15241 taacaccaac atcgccagaa ctttgaaagc ttcgccaaat gcgaatgtcc aggccacccg
    15301 gcctttcgct ggtgtatgcg cctggtgacg ccaggcaaat atcataaaca aaacgttagg
    15361 cagaaagact gccaagcccc cgcttattgc agagacgccc cagaaggggt ctttgaggct
    15421 gaacagcaat ccacttgcta tcaccaccag taactgaacg agcagaagct tccgagcaac
    15481 gtttcgactc acgagcgaca cagacatcac gtttttcact cctgctccct tcgaggtatg
    15541 ccgcgtgtcg tataaaactt tctttaaggc ttagagtcaa gcatcaaaaa gcggtcaaat
    15601 tatacggtgc gcccccgtga tttcaaacaa taagtagcca aaaggtgaat aaatgtttaa
    15661 atatttttcc agtgcataca attgcgactt ttctgcaaac cctgttcgat catgaaaaac
    15721 tgtaaataac gcgtaaacac tggtgataaa gcgtgcttca gatcacatat tgcgcatgtt
    15781 cgcgcacagc atatttattt acttggcaaa tgatgccttt gcaagtttat gatatttcag
    15841 tctaaaaaca gatactgttt taataaatga catttacata acaaaaacca gccattgaca
    15901 tttttaataa tgttttaaca gtcaatgatg attcttagcg ccgattttta gcagactgat
    15961 attttcactt atgacttatt ttctgcttac caaaaaaagc cacgttatct tgttgataca
    16021 aaagagtgaa cgtggcgtta aatgtaacca gttatatcag tagaaaacct ggttgttgtt
    16081 aacagtctaa ccggtcaatt ttttatgatt tttttgataa aaattaaatt ttatttgctt
    16141 taatcaccac cagatgacgt tcgccatcca gggctggaac ctgaagttta accactgatt
    16201 cgacctgata ttcttcgggc aacaaagcga tttcatcttc cggcatttgc cctttcagcg
    16261 cgtagaaacg gccttgctca ccaggaagat ggtggcacca gctcaccata tcgttcagag
    16321 aggcaaaagc gcggctaatt acgccatcaa atggcggctc tgacggaaac tcttctaccc
    16381 tgctctgtac tggctcaata ttctccagtt taagctcatg ttgcacctga cgaaggaaac
    16441 gcacgcgttt accaaggcta tccaacaacg tgaaatgagc ttcaggacgc acgatagaga
    16501 gtggaatgcc aggcagtccc ggtccggtgc cgacatcgat aaaccgttca ccttgcagat
    16561 acggtgccac cacaatgcta tcgagaatat ggcgtaccag catctcatta ggatcgcgga
    16621 ccgaagtcag gttgtacgct ttattccatt tatgcagcat attcacgtag gcaataagct
    16681 ggtttttctg gtgatcggta agcgaaatac ctgcgtcttt cagcagtaag gagagtttgt
    16741 tgagcacggt gattacctgt tcttgatgcg ttgcctggta agcgggtgct taccaggcat
    16801 ttttaatgcg ttatgcgcta cgacgcagca taccctgttt tttcagccac accagcagaa
    16861 tggagatagc cgcaggcgtg acgccagaaa tacgcgaagc ctggccaata gaggccggtt
    16921 tgtgatcgtt aagtttggcg atcacttcgt tagaaagacc ggatacctgg cggtaatcca
    16981 gcgtcgctgg tagcagggta ttctcgttac gcagctgctt ttcgatctca tcttgctggc
    17041 gcgcgatata accttcgtat ttaacctgaa tctcaacctg ttccgcagcc tgttcatctg
    17101 tcaacgcagg ggcaaacggt gtcagcgtgg ttaatttttc ataagtcatt tcaggacgac
    17161 gtagcagatc ttcaccactg gcttcacggg aaagcggcgc agtcaggtga gcattcactt
    17221 cggctgcagc ttccgccgac ggggttaccc aggtcgattt cagacgctga cgctcacgct
    17281 cgatattctc aagtttctcg ttaaagcgcg cccaacgttc gtcatccacc aggcccagtt
    17341 cacgaccgat ttcagtcaaa cgcagatcag cattatcttc gcgcagcatc agacgatatt
    17401 ctgcgcgcga ggtaaacata cgatacggtt ctttggttcc taaagtgcac aggtcatcaa
    17461 ccagtacgcc gagatacgcc tgagaacgcg ccggagccca accttctttg tcagcagaca
    17521 gacgggcagc gttaagacca gccagcaaac cttgcgcagc ggcttcttcg taaccggtag
    17581 tgccgttaat ctgaccagca aagaacagcc cctggataaa cttgctctcc agcgtcggtt
    17641 tcaggtcgcg tggatcgaag aagtcatact caatggcata acccggacgc acgatcttcg
    17701 cgttttccat cccctgcatg gagcggacga tttgcatctg cacatcgaac ggcaggctgg
    17761 tggagatacc gttcggataa atttcgttag aggtcagccc ttccggttca aggaagatct
    17821 gatgctgatt tctgtcggca aagcgcatga ctttgtcttc aatcgacggg cagtagcgtg
    17881 ggccgacacc ttcgatcacc cctgcgtaca ttgggctacg atcgagatta ctgcggatca
    17941 catcatgggt tttctcgttg gtatgagtga tataacacgg cacctgctgg ggatgctggg
    18001 acgcattgcc cataaacgag aataccggca ttgggttatc gccatgctgt tgcgccagta
    18061 cgctaaagtc gatggttcga gcatcaatac gcggtggtgt cccggttttc agacgaccaa
    18121 cgcgcagcgg cagttcacgc aaacggcgag aaagcggaat ggacggcgga tcaccagcac
    18181 ggccaccgct gtaattatcc agaccgatat gaattttacc gtcgaggaac gtcccaacgg
    18241 tgagcacgac agctttggca cggaacttca gtcccatttg ggtaacggca ccgaccacgc
    18301 gatcgttttc gacaataaga tcttcaaccg cctgctggaa gatcatcagg ttcggttggt
    18361 tctccagcgc cgtacgtacc gcctgacggt agagcacacg atctgcctga gctcgggtag
    18421 cgcgaaccgc cggtcccttg cttgcgttta gtatcctaaa ctggataccc gcctgatcga
    18481 tcgctttcgc catcagaccg ccgagtgcat ccacttcttt taccagatgt cccttcccaa
    18541 taccgccgat cgccgggttg cagctcatct gccccagagt gtcgatattg tgtgtcaaaa
    18601 gcagagtctg ttgacccata cgcgccgcgg ccatcgcggc ctcggtgcct gcatgacccc
    18661 cgccaatgat gatgacgtca aaaggatccg gataaaacat ggtgattgcc tcgcataacg
    18721 cggtatgaaa atggattgaa gcccgggccg tggattctac tcaactttgt cggcttgaga
    18781 aagacctggg atcctgggta ttaaaaagaa gatctattta tttagagatc tgttctattg
    18841 tgatctctta ttaggatcgc actgccctgt ggataacaag gatccggctt ttaagatcaa
    18901 caacctggaa aggatcatta actgtgaatg atcggtgatc ctggaccgta taagctggga
    18961 tcagaatgag gggttataca caactcaaaa actgaacaat cgttgttctt tggataacta
    19021 ccgtttgatc caagcttcct gacagagtta tccacagtag atcgcacgat ctgtatactt
    19081 atttgagtaa attaatccac gatcccagcc attcttctgc cggatcctcc ggaatgttgt
    19141 gatcaagaat gttgatcttc agtgtttcgc ctgtctgttt tgctccggaa tttttgagtt
    19201 ctgcctcgat tttatcgata gccccacaaa aggtgtcata ttcacgacta ccaataccga
    19261 ttgcgccaaa gcggaccgca gaaagatcgg gcttctgttc ctgcaatgct tcatagaaag
    19321 gagaaaggtt gtccggaata tctccggcac cgtgggttga gctgataacc agccagatcc
    19381 ccgaggcaga taaatcttcc aacagcggac cgtgcagcgt ttcggtggta aaacccgcct
    19441 cttccagctt ttcagccagg tgttctgcta catattcggc accgccgagg gtgctgccgc
    19501 tgataagagt gatatctgcc ataaaccgcc acctttatta agagtggcgt attgtacgct
    19561 gtgaacgcgt tgggatctac ctgtggaaaa gtatgggatt aaaaaagccg atcagggctt
    19621 aatggtacgc atgatcgggt tctgcaggac gatcagtgtc tcggtggact gaatttcatc
    19681 aattgtttgg atcttgttga taagtacatg ctggagagca tcgatcgaac ggcacatcac
    19741 ttttataaag atgctgtagt ggccggttgt gtaataggct tcagtgactt catcgaggct
    19801 ttccagcttt gccagcgcgg aaggatagtc tttggcgctc tttaatataa tgccgataaa
    19861 gcagcctacg tcataaccaa gctgcttcgg gctgacatca atacgcgccc cggtaatgat
    19921 ccccgcctgc ttcattttct ctactcgaac gtgaatcgtc cccggactga cgccaaattg
    19981 tttcgccagt tcggcgtaag cggtgcgcgc attgcccatt aatgcttcca ggatgccacg
    20041 gtccagattg tcgatcagat aattttccat aggattttct tatgcggatt gatgattcat
    20101 tctattttag ccttcttttt taatgaatca aaagcacgtg aggcttttta ttgaatgatt
    20161 attgcatgtg tgtcggtttt tgttgcttaa tcataagcaa caggacgcag gagtataaaa
    20221 aatgaaaacc gcttacattg ccaaacaacg tcaaattagc ttcgtgaaat ctcacttttc
    20281 tcgtcaactg gaagaacgtc tggggctgat cgaagtccag gcgccgattc ttagccgtgt
    20341 gggggatggc acgcaggata acttgtcggg ctgtgaaaaa gcggtgcagg taaaagtgaa
    20401 agctctgcct gatgcccagt tcgaagtggt tcattcactg gcgaagtgga aacgtcagac
    20461 cttagggcaa cacgacttca gcgcgggcga agggctgtac acgcacatga aagcccttcg
    20521 ccccgatgaa gaccgtcttt ccccgttgca ctcggtctat gtagaccagt gggactggga
    20581 acgcgtaatg ggcgacggcg agcgtcaatt ctcgactctg aaaagcacgg tagaggcgat
    20641 ctgggcggga attaaagcaa ccgaagctgc ggttagcaaa gagtttggcc tggcaccgtt
    20701 cctgccggat cagatccact tcgtacacag ccaggagtta ctgtctcgtt atccggatct
    20761 cgatgccaaa gggcgtgagc gggcgattgc gaaagatctt ggcgcggtat tcctcgtcgg
    20821 gattggcggc aagttgagtg atggtcatcg tcacgacgtg cgcgcaccgg attatgatga
    20881 ctggagcacc ccgtcagagc tgggccatgc gggtctgaac ggcgatattc tggtgtggaa
    20941 cccggtactg gaagatgcgt ttgagctttc ttccatgggg atccgcgtgg atgccgacac
    21001 gctgaagcat cagctggcgc tgaccggtga cgaagatcgc ctggagctgg agtggcatca
    21061 ggcgctgctg cgcggtgaaa tgccgcagac catcggcggc ggtatcgggc agtctcgttt
    21121 gaccatgctg ctgctgcaac tgccacatat cggccaggtt cagtgtggtg tatggccggc
    21181 agctgttcgc gagagcgtcc cttctctgct gtaataattt atcgccgcca gcgtctgagc
    21241 aggcggcttc gcatcccggt atcaaagcgc cagatatgat cgaaaatgcg catgatgccg
    21301 ggtttgccat gtgcagacat cgccacggca tgaaagcgat gctgatgtac ccgctgtagc
    21361 tctttcactt tactcgtcac gtcgtcaggc aaccgctggg cgataaaatc agaaatcacc
    21421 accgcatcgg catcaaacca ttcccggctt tgcaagcgtt ccataatggc gcgaaaacaa
    21481 ctggcaagat cggtgccgcc acgaaactgc tgacttaaaa aacggattgc ttgttcgatg
    21541 ccttgtgggc ctgaaagctc ataacggacg atctcggtgg aaaatagcat aatatagcag
    21601 cgccggtttt cagcgagagc aatgcgcatc aaggccaggc agaacgcttt cgcacactgt
    21661 tcattaaagc cgcccattga gccggaagta tccacacaga caataaacgg tccgcgcggc
    21721 tgttcgtcgt aatctttatg caccaccggg cgttcgatca ctttttcacg ccacgactca
    21781 ccatgcaggc gataggtgag caactgtttt tccaccagcc gacggtaaaa ctcatactcc
    21841 agttctgtta tccctagtgt cgccagttct ggcggcagga gacgtaaaat atcatcgctt
    21901 tgttgcagac catcaacctg ctcaggaacc gtcgccggtt cgcgcaccag ggtgcggaag
    21961 gtttccatct gcgcatcgtt gcgcggtatt gatttggctt cccgggaacg ccccagctgt
    22021 tctgccaggc gtttcagttc cggctgttcg ttaagaaatt caccgtattt cacaatcaac
    22081 tgatagtcgc cacgtttaag ctgaccggcg ctcatatccc acagacgacc agctgcggta
    22141 ttgttatctg cgagaatcgg ttcaagttgt ccgctcagcg tcatgcgttc ctgaacttca
    22201 ctcaacagtt gttcgcgttc ttcttctaat agctgttgat ttaacgtcgt tgcttgcacg
    22261 atcagactta aacgccaacg ctggagaaaa agcgtgtgta acgctgaagt gatcgtgctg
    22321 ttagcatcaa ccaactgtcg ggcttgttct gcccatgggg aattcagacg atgcagtaag
    22381 tccaggatct gtggtagctg cacaataaac tgcggcgtgg agaggagctg gctttgctga
    22441 tagcacatca cctcttcggt gagttccggc gggactcggg catctttcag ccgactgcgc
    22501 agcgcctcac gccagcgggg aacatcatca gtgattgccg ccttcagtcg tgggaatttt
    22561 tcaaagaaga ctgccagctg cggtgaggcc agcagcgcga tgatcatctc ttcgatcaat
    22621 ccctcttcgc tgacggccag catcacatta agcgtatcca gcgttagcat tgttgtgcct
    22681 ggcgaatctg tgcgccgaca tcctgtaggc tggcttcaat gcgacctaac cagtcgccag
    22741 ggataaacag acatttttgc tgttcgctga ataaagcgtg ttgcttgcgc cagtcgcttt
    22801 caagctcttc cagttgttgt tttatttcac ctggcagacc ttcagccgat gaaccgggaa
    22861 gtgccagcgt actgccttgt aaacttacat cgcgtacaac aagatgttgg gcgctatcca
    22921 cttccagatt cagtttctgg gcaaagccga taccgttcag tttgccgcga atctcaccac
    22981 ctttactcag ccactgttcc agcgcgctac gctcaaagga gatatgaacc acttccatat
    23041 catgcaattt taacggtttt tgcagcagca gagtcagagt ggaagcagta acgttaacag
    23101 gaagttgata ctgctgacga cggctgaaaa tgccgcccag acgaattacc gttaaggctg
    23161 ttttatcgct ttgttgctgc tggagttgca ggtgacgttg cacaatcgcg cccaggcggg
    23221 tcaacatccc ttgctgttgc caggcatgac cggtcatcaa tacatcaatt tgttgttgta
    23281 tcaaattcag gctttgcgcg tcataccaca ggcaatcttt cagcaaaatg agatcaaccg
    23341 gggcaacagc actgcgaccg ctaaaaaagg cgctggcctg caataagcgg atcgcttttt
    23401 tccagcgacg atccgagaca taaggcgcat ccggtaattt atccagttgc tggcgcagca
    23461 taaaaatcag ctcaaataca tgatcgggca gcgtaatttc accaatctct ttctgccagc
    23521 gttcatattc ttcatctgtg atctgcaagg aggcaggaac cggattgtca ttttcatcct
    23581 gttgactggt cagcatggag cggaaattcg ctttatcctg cactttatct aaccacagac
    23641 gaatcagcat gcggtcatat aacgcttcca gactgctgtc tgcttccggc agctcgttgg
    23701 aggccgccac cagcagacgc atcgggattt tttctacgag tgcgccgttg cggaactggc
    23761 gctcgttaat ggcggtgagc aaggtattaa gaattgccgg acccgctttc cagatctcat
    23821 ccagaaagac gatttcagct tccggcaggt aaccgctggt taaacgttca tagcgccctt
    23881 catcttttag cgcctgaata gaaaggggac caaaaacttc ttccggcgtg gagaagcggg
    23941 tcatcagata ttcaaacgcg cgggcattct gaaaggcgaa ttttaagcgc cgggcgatca
    24001 aacttttggc aatacctggt gggccaagga ggaacacact ttcaccactt aatgccgcta
    24061 ataaacacaa gcggatggcg tggctacgtt cataaagccc cttttccaac gaactgctca
    24121 ggcgggaaat tctttccgct aataaatgag ggtgagccat aatgaagtgg cgtcctttca
    24181 tcaaaagttc tgcgtaaatt gcgagtatag acgtttcttg ctggtggcta aaatagtctc
    24241 aaaggagggg tatttttctt tgagccaggt taatgtggcc gcatttagga gtacgatttt
    24301 gccgttaatc gtgcatactg tgcgcttttt tgtgggccaa gggactaagc acacatttca
    24361 tatttcaacg aaagactagt ctatgagcac tgataataag caatcattgc ccgcgattac
    24421 cctcgcggcg attggagttg tctacggcga tattggtacc agcccgttat atacacttcg
    24481 tgaatgtttg tccggccagt ttggttttgg cgttgaacgc gatgccgtgt ttggcttttt
    24541 atcgctgatc ttctggctgc taatctttgt ggtttccatt aaatatctca ccttcgtgat
    24601 gcgggcagat aacgccggtg aaggggggat cctgacgttg atgtcgcttg ccgggcgtaa
    24661 tacgtcggcg cgaaccacat caatgctggt gattatgggg ctaatcggcg gcagcttttt
    24721 ctatggtgaa gtcgtcatta ctcccgctat ttcggtgatg tccgccattg aaggtctgga
    24781 aatcgtcgcc ccgcagctgg atacctggat agttcccctc tcaattatcg ttctcacatt
    24841 attattcatg attcaaaaac atggcacagc tatggtcggt aagctgtttg cgccgatcat
    24901 gctgacctgg tttttgattc tggcagggct ggggttacgt agcattattg ctaacccgga
    24961 agtgctgcat gcactgaatc cgatgtgggc ggtgcatttc ttccttgaat acaaaacggt
    25021 ttcttttatt gcattagggg cagtggtgct gtcgattacg ggggtcgagg cgctgtatgc
    25081 tgatatgggg cactttggta agttccctat tcgtctggcg tggttcaccg tcgtattgcc
    25141 ttccttaacc cttaattact tcggccaggg agcgctgttg ttaaagaatc cggaagcgat
    25201 taagaacccg ttcttcctgt tggcaccgga ctgggcgctg atcccgctgc tgatcatcgc
    25261 cgcactggcg acggtaattg cctcgcaggc ggttatctct ggcgtcttct cattgacgcg
    25321 tcaggcggta cgtctgggat atttgtcgcc gatgcgcatt attcacacct ccgaaatgga
    25381 gtcagggcaa atctatattc cctttgtgaa ctggatgctc tatgtcgcgg tcgtgattgt
    25441 gattgtcagc tttgagcact ccagcaacct ggcggcggcg tacgggattg cggtgaccgg
    25501 aaccatggtg ctgacgtcta ttctctcgac taccgtggca cgtcagaact ggcactggaa
    25561 taagtatttt gttgcgctga tcctgattgc tttcctttgt gtcgatattc ccttgttcac
    25621 cgctaacctc gataaactgc tctccggtgg ctggttgcca ttgagcctcg gtacggtgat
    25681 gtttatcgtg atgaccacct ggaagagcga gcgtttccgc ttgctgcggc ggatgcatga
    25741 acatggtaac tctctggaag cgatgattgc ttcgctggag aaatcaccgc ccgttcgcgt
    25801 gcctgggacc gcggtgtata tgtcgcgtgc aatcaacgtc attccctttg cgctgatgca
    25861 taaccttaaa cataacaagg tattgcatga gcgggtgatt ctgttaactc tgcgcaccga
    25921 agacgcgcca tatgtccata acgtccgtcg ggtacagatt gaacaactgt cgcccacttt
    25981 ctggcgcgtg gtggcaagtt atggttggcg agaaacgcca aacgtggaag aagttttcca
    26041 ccgctgcggt ctggaaggat taagctgccg gatgatggaa acctccttct ttatgtcgca
    26101 tgagtcgttg atcctcggca aacgcccgtg gtatttgcgt ctgcgcggca agctgtactt
    26161 gctgctgcaa cgtaatgcgc tgcgggcacc ggatcaattt gaaatcccgc caaacagagt
    26221 tatcgaactg ggtactcagg tcgaaatcta acgccagacg cctcctttct ccataagggg
    26281 gcgtttttgt tttcatggtt aatcaccatg taaaacgttt cgaggttgat cacatttccg
    26341 taacgtcacg atggttttcc caactcagtc aggattaaac tgcgggtcag cgaaacgttt
    26401 cgctgatgga gaaaaaaatg aaaaaaggca ccgttcttaa ttctgatatt tcatcggtga
    26461 tctcccgact gggacatacc gatacgctgg tggtgtgtga tgctggttta cccatcccca
    26521 aaagtacaac gcgtatcgat atggcattaa cccagggtgt accttctttt atgcaggtgc
    26581 tgggcgtcgt cacaaatgaa atgcaggtcg aggctgtcat tatcgcggaa gagatcaaac
    26641 aacataatcc gcaactccac gaaacgttgc tcactcacct tgagcagctg caacaacacc
    26701 agggaaacac cattgaaatt cgttacacca cgcatgaaca attcaaacaa caaaccgcag
    26761 aaagtcaggc ggtaattcgc agcggagaat gttctccgta tgcgaatatc attctctgtg
    26821 ctggcgtgac gttctgaggc cgtcatggaa gcattacttc agcttaaagg catcgataaa
    26881 gcctttccgg gcgtaaaagc cctctcgggc gcagcgttaa atgtctatcc gggccgcgtg
    26941 atggcgctgg tgggcgaaaa cggcgcgggt aaatccacca tgatgaaagt gcttactggt
    27001 atctatactc gcgatgccgg tacgctttta tggttgggga aagaaacgac atttaccggg
    27061 ccgaaatctt cccaggaagc cgggattggg attatccacc aggaactgaa cctgatcccg
    27121 cagttaacca ttgccgaaaa cattttcctc ggtcgtgagt ttgttaatcg ctttggcaaa
    27181 attgactgga aaaccatgta tgccgaagcg gataaattgc tggctaaact taacctgcgc
    27241 tttaaaagcg acaaactggt gggtgatctt tccatcggtg accagcaaat ggttgaaatc
    27301 gccaaagtgc tgagctttga gtcgaaagtc atcattatgg atgaaccgac cgatgcgctg
    27361 accgataccg aaaccgaatc cttgttccgc gtcatccgcg agctgaaatt gcaaggccgc
    27421 ggtattgtct atatctccca ccgcatgaaa gaaatcttcg agatttgcga tgacgttacc
    27481 gtttttcgtg acggacaatt tattgctgag cgtgaagtgg catcactgac cgaagattct
    27541 ctgattgaga tgatggtggg ccgcaagctg gaagatcaat atccgcacct ggacaaagcg
    27601 ccgggagata tccgcctgaa agtcgataat ctctgcggac ctggcgttaa cgatgtctct
    27661 tttactttac gcaaaggcga aattcttggc gtctctggtt tgatgggcgc tgggcgtacc
    27721 gaactgatga aagtgctcta cggcgcactg ccgcgcacaa gcggttacgt caccctggat
    27781 gggcatgaag tcgttacccg ttcgccgcag gatggcctgg caaacggcat tgtttatatc
    27841 tccgaagacc gtaaacgtga cggtttagtg ctgggcatgt cagtaaaaga gaacatgtcg
    27901 ctgaccgcgc tgcgctactt cagccgcgct ggcggcagtt tgaagcatgc cgatgaacag
    27961 caggctgtga gtgatttcat tcgtctgttt aatgtgaaaa cgccatcgat ggaacaggca
    28021 attggtctgc tttccggtgg caatcagcaa aaagtagcga ttgcccgtgg tctgatgaca
    28081 cgccctaaag tgttgatcct cgatgagcct acccgtggcg tagatgtcgg cgcgaaaaaa
    28141 gagatctatc aactgattaa ccagttcaaa gccgatggct tgagcatcat tctggtgtca
    28201 tcggagatgc cagaagtatt aggcatgagc gatcgcatca tcgtcatgca tgaagggcat
    28261 ctcagcgggg aatttactcg tgagcaggcc acccaagaag tgttaatggc tgccgctgtg
    28321 ggcaagctta atcgcgtgaa tcaggagtaa aaaaatgaca acccagactg tctctggtcg
    28381 ccgttatttc acgaaagcgt ggctgatgga gcagaaatcg cttatcgctc tgctggtgct
    28441 gatcgcgatt gtctcgacgt taagcccgaa ctttttcacc atcaataact tattcaatat
    28501 tcttcagcaa acctcggtga acgccattat ggcggtcggg atgacgctgg tgatcctgac
    28561 gtcgggtatc gacttgtcgg taggttctct gttggcgctg accggcgcag ttgctgcatc
    28621 tatcgtcggc attgaagtca atgcgctggt ggctgtcgct gccgctctcg cgttaggtgc
    28681 cgcaattggt gcggtaactg gggtgattgt agcgaaaggt cgcgtccagg cgtttatcgc
    28741 tacgctggtt atgatgcttt tactgcgcgg cgtgaccatg gtttatacca atggtagccc
    28801 agtgaatacc ggctttactg agaacgccga tctgtttggc tggtttggta ttggtcgtcc
    28861 gctgggcgta ccgacgccag tctggatcat ggggattgtc ttcctcgcgg cctggtacat
    28921 gctgcatcac acgcgtctgg ggcgttacat ctacgcgctg ggcggcaacg aagcggcaac
    28981 gcgtctttct ggtatcaacg tcaataaaat caaaatcatc gtctattctc tttgtggtct
    29041 gctggcatcg ctggccggga tcattgaagt ggcgcgtctc tcctccgcac aacccacggc
    29101 ggggactggc tatgagctgg atgctattgc tgcggtggtt ctgggcggta cgagtctggc
    29161 gggcggaaaa ggtcgcattg ttgggacgtt gatcggcgca ttaattcttg gcttccttaa
    29221 taatggattg aatttgttag gtgtttcctc ctattaccag atgatcgtca aagcggtggt
    29281 gattttgctg gcggtgctgg tagacaacaa aaagcagtaa taacgactac aggacatctt
    29341 gaatatgaac atgaaaaaac tggctaccct ggtttccgct gttgcgctaa gcgccaccgt
    29401 cagtgcgaat gcgatggcaa aagacaccat cgcgctggtg gtctccacgc ttaacaaccc
    29461 gttctttgta tcgctgaaag atggcgcgca gaaagaggcg gataaacttg gctataacct
    29521 ggtggtgctg gactcccaga acaacccggc gaaagagctg gcgaacgtgc aggacttaac
    29581 cgtccgcggc accaaaattc tgctgattaa cccgaccgac tccgacgcag taggtaatgc
    29641 tgtgaagatg gctaaccagg cgaacatccc ggttatcact cttgaccgcc aggcaacgaa
    29701 aggtgaagtg gtgagccaca tcgcatctga taacgtactg ggcggcaaaa tcgccggtga
    29761 ttacatcgcg aagaaagcgg gtgaaggtgc caaagttatc gagctgcaag gcattgccgg
    29821 tacatccgca gcccgtgaac gtggcgaagg tttccagcag gccgttgctg ctcacaagtt
    29881 taatgttctt gccagccagc ctgcagattt tgatcgcacc aaaggcttga acgtaatgca
    29941 gaacctgttg accgctcatc cggatgttca ggctgtattc gcgcagaatg atgaaatggc
    30001 gcttggcgcg ctgcgcgcac tgcaaactgc cggtaaatcg gatgtgatgg tcgtcggatt
    30061 tgacggtaca ccggatggcg aaaaagcggt gaatgatggc aaactagcag cgactatcgc
    30121 tcagctaccc gatcagattg gcgcgaaagg cgtcgaaacc gcagataaag tgctgaaagg
    30181 agagaaagtt caggctaagt atccggttga tctgaaactg gttgttaagc agtagtttta
    30241 atcaggttgt atgacctgat ggtgacataa atacgtcatc gacagatgaa cgtgtaatat
    30301 aaagaaaagc agggcacgcg ccaccctaac acggtggcgc attttatgga catcccgaat
    30361 atgcaaaacg caggcagcct cgttgttctt ggcagcatta atgctgacca cattcttaat
    30421 cttcaatctt ttcctactcc aggcgaaacc gtaaccggta accactatca ggttgcattt
    30481 ggcggcaaag gcgcgaatca ggcggtggct gctgggcgta gcggtgcgaa tatcgcgttt
    30541 attgcctgca ctggcgatga cagcattggt gagagcgttc gccagcagct cgccactgat
    30601 aatatcgata tttctccggt cagcgtgatc aaaggcgaat caacaggtgt ggcgctgatt
    30661 tttgttaatg gcgaaggtga gaatgtcatc ggtattcatg ccggcgctaa tgctgccctt
    30721 tccccggcgc tggtggaagc gcaacgtgag cgtattgcca acgcgtcggc attattaatg
    30781 cagctggaat caccactcga aagtgtgatg gcagcggcga aaatcgccca tcaaaataag
    30841 actatcgttg cgcttaaccc ggctccggct cgcgaacttc ctgacgaact tctggcgctg
    30901 gtggacatta ttacgccaaa cgaaacggaa gcagaaaagc tcaccggtat tcgtgttgaa
    30961 aatgatgaag atgcagcgaa ggcggcgcag gtactgcatg aaaaaggtat ccgtactgta
    31021 ctgattactt taggaagtcg tggtgtatgg gctagcgtga atggtgaagg tcagcgcgtt
    31081 cctggattcc gggtgcaggc tgtcgatacc attgctgccg gagatacctt taacggcgcg
    31141 ttaatcacgg cgttgctgga agaaaaaaca ttgccagagg cgattcgttt tgcccatgca
    31201 gccgctgcga ttgccgtaac acgtaaaggc gcacaacctt ccgtaccgtg gcgtgaagag
    31261 atcgacgcat ttttagacag gcagaggtga cgcttggcta caatgaaaga tgttgcccgc
    31321 ctggcgggcg tttctacctc aacagtttct cacgttatca ataaagatcg cttcgtcagt
    31381 gaagcgatta cagccaaagt tgaagcggcg attaaagaac tcaattacgc gccatcagct
    31441 ctggcgcgta gcctcaaact caatcaaaca cataccattg gcatgttgat cactgccagt
    31501 accaatcctt tctattcaga actggtgcgt ggcgttgaac gcagctgctt cgaacgcggt
    31561 tatagtcttg tcctttgcaa taccgaaggc gatgaacagc ggatgaatcg taatctggaa
    31621 acgctgatgc aaaaacgcgt tgatggcttg ctgttactgt gcaccgaaac gcatcagcct
    31681 tcgcgtgaaa tcatgcaacg ttatccgaca gtgcctaccg tgatgatgga ctgggctccg
    31741 ttcgatggcg acagcgatct tattcaggat aactcgttgc tgggcggaga cttagcaacg
    31801 caatatctga tcgataaagg tcatacccgt attgcctgta ttaccggtcc gctggataaa
    31861 actccggcgc gcctgcggtt ggaaggttat cgggctgcga tgaaacgtgc gggtctcaac
    31921 attcctgatg gctatgaagt cactggtgat tttgaattta acggcgggtt tgacgctatg
    31981 cgccaactgt tatcacatcc gctgcgtcct caggccgtct ttaccggaaa tgacgctatg
    32041 gctgttggcg tttaccaggc gttatatcag gcagagttac aggttccgca ggatatcgcg
    32101 gtgattggct atgacgatat cgaactggca agctttatga cgccaccatt aacaactata
    32161 caccaaccga aagatgaact gggggagctg gcgattgatg tactcatcca tcggataacc
    32221 cagccgaccc tacagcaaca acgattacaa cttactccga ttctgatgga acgcggttcg
    32281 gcttagattt acgctgtctt ttgatcaaat tattaccatc ggttgttttc agtagcatga
    32341 acattgctgc tgaagcaaca gtaataatgc ccatcgtgat aaacgtatag tggaattgtt
    32401 cgactgtcgt tgtgccttcc atcccttcgt aaacgcgaag gacggccgca cttacagcaa
    32461 cgcctaaact gatagacagt tgctgcgtga ccgccagaac actgttaccg ctgctggcgt
    32521 tgtcatcggt cagatcggca agtgtgatgg tattcatcgc ggtaaattgc gtcgacatag
    32581 ccatccctaa tataaacaac ggcaagatca gcatccatat cgccattgct ggtgattgca
    32641 aagagaactg agcgatcatt agcccaataa tcaccgtgat ccccactaac gtatggcgat
    32701 agcccagacg acgtaagact tgggtaacca tcgattttgc aataatggaa cctaacgctg
    32761 tcggtgccat catacagcca gcaataaacg cctgataccc aaatcctacc tgtaacatca
    32821 atggcataag gaacggtaca cagccggtcc ccagacgggt tgcaatattg cctacgatac
    32881 cgatcgagaa agtgcgggtt ttaaataaat ctaatgaaat taatgggttt ggcgtgcgtc
    32941 gcgcatggag aatatagaga agcagtaact agatgctggt gacaattacc gtcaaggcaa
    33001 tccagctggc gacaatcttt tccccgaata gctctattcc gcttgagaag agaacaaggc
    33061 tgaggccaaa cagcaaaaag ccagtggtat cgaatctgcg tcgtgcggtg gtgaaattgg
    33121 gcatatgttt gcgcgcgtaa agaaggcccg caatacctat ggggatattg attaaaaata
    33181 tccagtgcca ggttgcccag gtgaccagca cgccgccaag aacggggcct aaaattggcc
    33241 ccaccagacc cggcatggcg acaaaattca atacaggaag aagttcatta cgaggataag
    33301 cgcgcagtaa ggccagccga gcaacaggca tcatcattgc gccgcctatc ccctgaataa
    33361 cccggaagac aaccagctgt ggtagcgagt tggaaagtgc gcaggccaga gaacccaacg
    33421 tgaacagact cacggcaagg gtaaaaatgc gacgcgtacc gaagcgatcg gctagccatc
    33481 cgcttaccgg aataagcatc gccaccgtca gcgtataact gatgatggct gattgcatcg
    33541 cgagaggaga acgattaagg ctatgagcga ttgcgggtaa ggcggtattc agaatagtgg
    33601 catcaagtgc ctgcatgaag aaggccatcg ccgcgatcca cggcaaaccc gccatactgc
    33661 gcttcttttt atcgctcatt caaagtcctg ttatcgggtt atcacttatc tggtgagcgt
    33721 agcagcgcct gacaagcttt aaatgccgcg tcgccatcgc tttggataat cgcatcgaca
    33781 atcgcctggt gcagatccag ctttatcact gtgtcgctgg taattgacgt gaagtaagtg
    33841 tgataaaccg aatggaatag cgaggcgaat gaggtcaaaa acggattggc gctcatttca
    33901 tagatatgct catgccaggc catatcgact tcgatccagc gttcacggcg aaagttctct
    33961 tttaatgccg ccatttcggc cattaacgta ttgagatgcg ccttctgttc cgcggtgcca
    34021 accgttgctg ccagtaggca agcttgcggc tccagacaga tacgcataac cagaaagtga
    34081 tcgatgacct gatgaaagtt ctcttctgtc atccaccagg taagcaattc ctgatcaaga
    34141 aaattccagt tcgattgtgg catgactcgg gtaccaattc gcggtcgcgg taaaaccatc
    34201 ccttttgccg ttaacgtttt gaccgcttcg cgtaccgctg tacgactcac tccaaattgc
    34261 tcgcccagct caatctcacc aggcaaaatg gtgccgggtt catattcacc ttttaagatc
    34321 cgctgcgcca gcttttcagc cagaacatac gaaaggtttt tctgtgcagc taactgttgt
    34381 gcgcttaaag gcattactaa tcttcctttt tctttttatt cctccttagt atgccaccag
    34441 gaagtgtgat tacggttgca aaaacggcaa attgcttgtt ttatggcaca ttaacggggc
    34501 ttttgctgaa aaa
//
LOCUS       DAPOXO010000052        34436 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPOXO010000052 DAPOXO010000000
VERSION     DAPOXO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34436
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.052"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..791)
                     /gene="map"
                     /locus_tag="ROH59_002941"
     CDS             complement(<1..791)
                     /gene="map"
                     /locus_tag="ROH59_002941"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDX4805396.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD"
     gene            1159..1884
                     /gene="rpsB"
                     /locus_tag="ROH59_002942"
     CDS             1159..1884
                     /gene="rpsB"
                     /locus_tag="ROH59_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDX4805397.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            2019..2870
                     /gene="tsf"
                     /locus_tag="ROH59_002943"
     CDS             2019..2870
                     /gene="tsf"
                     /locus_tag="ROH59_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDX4805398.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            3017..3742
                     /gene="pyrH"
                     /locus_tag="ROH59_002944"
     CDS             3017..3742
                     /gene="pyrH"
                     /locus_tag="ROH59_002944"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDX4805399.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            3892..4449
                     /gene="frr"
                     /locus_tag="ROH59_002945"
     CDS             3892..4449
                     /gene="frr"
                     /locus_tag="ROH59_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDX4805400.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            4541..5737
                     /gene="ispC"
                     /locus_tag="ROH59_002946"
     CDS             4541..5737
                     /gene="ispC"
                     /locus_tag="ROH59_002946"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDX4805401.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALKDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            5926..6684
                     /gene="ispU"
                     /locus_tag="ROH59_002947"
                     /gene_synonym="uppS"
     CDS             5926..6684
                     /gene="ispU"
                     /locus_tag="ROH59_002947"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HDX4805402.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            6697..7554
                     /gene="cdsA"
                     /locus_tag="ROH59_002948"
     CDS             6697..7554
                     /gene="cdsA"
                     /locus_tag="ROH59_002948"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDX4805403.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRIIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLVTAAVISWGYGMWVNLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            7566..8918
                     /gene="rseP"
                     /locus_tag="ROH59_002949"
     CDS             7566..8918
                     /gene="rseP"
                     /locus_tag="ROH59_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HDX4805404.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            8948..11380
                     /gene="bamA"
                     /locus_tag="ROH59_002950"
     CDS             8948..11380
                     /gene="bamA"
                     /locus_tag="ROH59_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HDX4805405.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            11502..11987
                     /gene="skp"
                     /locus_tag="ROH59_002951"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             11502..11987
                     /gene="skp"
                     /locus_tag="ROH59_002951"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HDX4805406.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            11991..13016
                     /gene="lpxD"
                     /locus_tag="ROH59_002952"
     CDS             11991..13016
                     /gene="lpxD"
                     /locus_tag="ROH59_002952"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HDX4805407.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            13121..13576
                     /gene="fabZ"
                     /locus_tag="ROH59_002953"
     CDS             13121..13576
                     /gene="fabZ"
                     /locus_tag="ROH59_002953"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDX4805408.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            13580..14368
                     /gene="lpxA"
                     /locus_tag="ROH59_002954"
     CDS             13580..14368
                     /gene="lpxA"
                     /locus_tag="ROH59_002954"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HDX4805409.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            14368..15516
                     /gene="lpxB"
                     /locus_tag="ROH59_002955"
     CDS             14368..15516
                     /gene="lpxB"
                     /locus_tag="ROH59_002955"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HDX4805410.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNGARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            15513..16109
                     /gene="rnhB"
                     /locus_tag="ROH59_002956"
     CDS             15513..16109
                     /gene="rnhB"
                     /locus_tag="ROH59_002956"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDX4805411.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPSMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     gene            16146..19628
                     /gene="dnaE"
                     /locus_tag="ROH59_002957"
     CDS             16146..19628
                     /gene="dnaE"
                     /locus_tag="ROH59_002957"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDX4805412.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAESRGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLDTELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            19641..20600
                     /gene="accA"
                     /locus_tag="ROH59_002958"
     CDS             19641..20600
                     /gene="accA"
                     /locus_tag="ROH59_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDX4805413.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            20698..22839
                     /gene="ldcC"
                     /locus_tag="ROH59_002959"
     CDS             20698..22839
                     /gene="ldcC"
                     /locus_tag="ROH59_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HDX4805414.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RGEFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDSWF
                     FDIWQPPQVDEAECWHVAPGEQWHGFSDADANHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTEESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            22896..23285
                     /locus_tag="ROH59_002960"
     CDS             22896..23285
                     /locus_tag="ROH59_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDX4805415.1"
                     /translation="MLGLKQVHHIAIIATDYAMSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            23350..24663
                     /gene="tilS"
                     /locus_tag="ROH59_002961"
     CDS             23350..24663
                     /gene="tilS"
                     /locus_tag="ROH59_002961"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDX4805416.1"
                     /translation="MTLTLNRQLLSSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTL
                     RAIHVHHGLSANADAWVKHCENICQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELEQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQTQQGTLKIAPMLAMSDARRAAIIRRWLAGQNAPMPSREALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVAGQSETIVPWQTWLQPLELPA
                     GLGSVQLTAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAVGENGVSFVWQKTLSQVKAG"
     gene            complement(24697..24957)
                     /gene="rof"
                     /locus_tag="ROH59_002962"
     CDS             complement(24697..24957)
                     /gene="rof"
                     /locus_tag="ROH59_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HDX4805417.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGATRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(24944..25144)
                     /locus_tag="ROH59_002963"
     CDS             complement(24944..25144)
                     /locus_tag="ROH59_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HDX4805418.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            25310..25855
                     /locus_tag="ROH59_002964"
     CDS             25310..25855
                     /locus_tag="ROH59_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HDX4805419.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFAYNSRAAQIWWQQNQSKCAQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTVWQQPS"
     gene            25852..26274
                     /gene="arfB"
                     /locus_tag="ROH59_002965"
     CDS             25852..26274
                     /gene="arfB"
                     /locus_tag="ROH59_002965"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDX4805420.1"
                     /translation="MIVISRHVAIPDGEFEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAVIKDLTTEQ
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            26288..26998
                     /gene="nlpE"
                     /locus_tag="ROH59_002966"
                     /gene_synonym="cutF"
     CDS             26288..26998
                     /gene="nlpE"
                     /locus_tag="ROH59_002966"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308221.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HDX4805421.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAKSSMPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERGYLAARGNGEKPVLLSVEGHFTLEANPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGQ"
     gene            complement(27154..27978)
                     /locus_tag="ROH59_002967"
     CDS             complement(27154..27978)
                     /locus_tag="ROH59_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
                     /protein_id="HDX4805422.1"
                     /translation="MDKPKAYCRLLLPCFLLLSACTVDISQPDSSATAVNAEAKTWAV
                     KFQHQSSFTEQSIKEITEPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIYLGNNN
                     VAEATGAGVQIVSLKKAMKHSDKLFVLRVPDLTPQQATEITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSNVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRSGDVSAFKPETQLQYIGHLKPGIYIKASRFVGLTQ"
     gene            complement(28031..29749)
                     /gene="proS"
                     /locus_tag="ROH59_002968"
     CDS             complement(28031..29749)
                     /gene="proS"
                     /locus_tag="ROH59_002968"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDX4805423.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVLMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYL
                     VKQIKG"
     gene            complement(29860..30567)
                     /gene="tsaA"
                     /locus_tag="ROH59_002969"
     CDS             complement(29860..30567)
                     /gene="tsaA"
                     /locus_tag="ROH59_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HDX4805424.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVCFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(30564..30968)
                     /gene="rcsF"
                     /locus_tag="ROH59_002970"
     CDS             complement(30564..30968)
                     /gene="rcsF"
                     /locus_tag="ROH59_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HDX4805425.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(31086..31901)
                     /gene="metQ"
                     /locus_tag="ROH59_002971"
     CDS             complement(31086..31901)
                     /gene="metQ"
                     /locus_tag="ROH59_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HDX4805426.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(31941..32594)
                     /gene="metI"
                     /locus_tag="ROH59_002972"
     CDS             complement(31941..32594)
                     /gene="metI"
                     /locus_tag="ROH59_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HDX4805427.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTISAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(32587..33618)
                     /gene="metN"
                     /locus_tag="ROH59_002973"
     CDS             complement(32587..33618)
                     /gene="metN"
                     /locus_tag="ROH59_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HDX4805428.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            33806..34378
                     /gene="gmhB"
                     /locus_tag="ROH59_002974"
     CDS             33806..34378
                     /gene="gmhB"
                     /locus_tag="ROH59_002974"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HDX4805429.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMFLSARDYLHIDMAASYMVGDKLEDMQAAAAASVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPA"
BASE COUNT         8322 a         8367 c         9443 g         8304 t
ORIGIN      
        1 tcgtcgtgcg agattatcgc cgggatggtg tcatccttgc gtagcgtcag aatttcgcag
       61 ccgttatcag tcaccacaat agtatgctca tattgtgcag acaagctgcg atctttggtt
      121 tttaccgtcc agccatcttt catggtgcgg atctcttttt tacccgcgtt gaccattggc
      181 tcgatggtga atgtcatccc cggtttcagc acgacgttgg tttcacggga gtcatagtgc
      241 agcacctgcg gttcttcgtg gaagccgcga ccaataccgt gtccgcaata ttcacgaacg
      301 acggagaagc cttctgcttc gacaaatttc tgaattgccg caccgatttc gcgcagatta
      361 atgcctggtt ttaccatgcg tagcgccagg tacaggcttt cttgcgtgat gcggcacaga
      421 cgttcgccca tgatggtcgg cttaccgacg ataaacattt tcgaggtatc gccgtggaaa
      481 ccatctttga ttacggtgac atcaatgtta acgatatcgc catctttcag cagcttggcg
      541 tcgtccggga taccgtggca caccacttca ttaatagaga tgcaaacgga tttcggatag
      601 ccgtgatagc cgaggcaggc agaaaccgcg tgttgttcat taacaatgta atcattacag
      661 atgcgatcca gctcgccggt gctgacgccc ggtttaacat acggttcgat catctccagc
      721 acttcggcag ccagtcggcc agcgacgcgc attttttcga tatcttctgg ggtcttgatt
      781 gagatagcca ttaattctgt ccatcagcgt cggtgatacc gacaatatat atgtaagtgc
      841 cgtcaatggt atcacacccg ggcaaattga gaatcattct gaatttcgcc aaacgtgcca
      901 ctgaaggttt tctataatag aaaattcaac gtctgatgct gtacacagcg ccaacaatta
      961 ttggtgtcca cgacgtattt gtggtataaa gcgcgccgga cttccgatcc atttcgtata
     1021 cacagactgg acggaagcga caatctcact ttgtgtaaca acacacacgt atcggcacat
     1081 attccggggt gccctttggg gtcggtaata tgggatacgt ggaggcataa ccccaacttt
     1141 tatatagagg ttttaatcat ggcaactgtt tccatgcgcg acatgctcaa ggctggtgtt
     1201 cacttcggtc accagacccg ttactggaac ccgaaaatga agccgttcat cttcggtgcg
     1261 cgtaacaaag ttcacatcat caaccttgag aaaactgtac cgatgttcaa cgaagctctg
     1321 gctgaactga acaagattgc ttctcgcaaa ggtaaaatcc ttttcgttgg tactaaacgc
     1381 gctgcaagcg aagcggtgaa agacgctgct ctgagctgcg accagttctt cgtgaaccat
     1441 cgctggctgg gcggtatgct gactaactgg aaaaccgttc gtcagtccat caaacgtctg
     1501 aaagacctgg aaactcagtc tcaggacggt actttcgaca agctgaccaa gaaagaagcg
     1561 ctgatgcgca ctcgtgagct ggagaaactg gaaaacagcc tgggcggtat caaagacatg
     1621 ggcggtctgc cggacgctct gtttgtaatc gatgctgacc acgaacacat tgctatcaaa
     1681 gaagcaaaca acctgggtat tccagtattt gctatcgttg ataccaactc tgatccggac
     1741 ggtgttgact tcgttatccc gggtaacgac gacgcaatcc gtgctgtgac cctgtacctg
     1801 ggcgctgttg ctgcaaccgt acgtgaaggc cgttctcagg atctggcttc ccaggcggaa
     1861 gaaagcttcg tagaagctga gtaataaggc acgctcgtac gagcccttat agaccaggta
     1921 gtacacgttt ggttaggggg cctgcatatg gccccctttt tcacttttat atctgtgcgg
     1981 tttaatgccg ggcagatcac atctccgagg attttagaat ggctgaaatt accgcatccc
     2041 tggtaaaaga gctgcgtgag cgtactggcg caggcatgat ggattgcaaa aaagcactga
     2101 ctgaagctaa cggcgacatc gagctggcaa tcgaaaacat gcgtaagtcc ggtgctatta
     2161 aagcagcgaa aaaagcaggc aacgttgctg ctgacggcgt gatcaaaacc aaaatcgacg
     2221 gcaactacgg catcattctg gaagttaact gccagactga cttcgttgca aaagacgctg
     2281 gtttccaggc gttcgcagac aaagttctgg acgcagctgt tgctggcaaa atcactgacg
     2341 ttgaagttct gaaagcacag ttcgaagaag aacgtgttgc gctggtagcg aaaattggtg
     2401 aaaacatcaa cattcgccgc gttgctgcgc tggaaggcga cgttctgggt tcttatcagc
     2461 acggtgcgcg tatcggtgtt ctggttgctg ctaaaggcgc tgacgaagag ctggttaaac
     2521 acatcgctat gcacgttgct gcaagcaagc cagaattcat caaaccagaa gacgtatccg
     2581 ctgaagtggt agaaaaagaa taccaggtac agctggatat cgcgatgcag tctggtaagc
     2641 cgaaagaaat tgcagagaaa atggttgaag gccgcatgaa gaaattcacc ggcgaagttt
     2701 ctctgaccgg tcagccgttc gttatggaac caagcaaaac tgttggtcag ctgctgaaag
     2761 agcataacgc tgaagtgact ggctttatcc gcttcgaagt gggtgaaggc atcgagaaag
     2821 ttgagactga ctttgcagca gaagttgctg cgatgtccaa gcagtcttaa ttatcgaaaa
     2881 ggagccgcct gagggcggct tctttttgtg cccatcttgt aaattcagct aacccttgtg
     2941 gggctgcgct gaaaagcgac gtacaatgtc gctagtatta attcatttca atcgttgaca
     3001 gtctcaggaa agaaacatgg ctaccaatgc aaaacccgtc tataaacgca ttctgcttaa
     3061 gttgagtggc gaagctctgc agggcactga aggcttcggt attgatgcaa gcatactgga
     3121 tcgcatggct caggaaatca aagaactggt tgaactgggt attcaggttg gtgtggtgat
     3181 tggtgggggt aacctgttcc gtggcgctgg tctggcgaaa gcgggtatga accgcgttgt
     3241 gggcgaccac atggggatgc tggcgaccgt aatgaacggc ctggcaatgc gtgatgcact
     3301 gcaccgcgcc tatgtgaacg ctcgtctgat gtccgctatt ccattgaatg gcgtgtgcga
     3361 cagctacagc tgggcagaag ctatcagcct gttgcgcaac aaccgtgtgg tgatcctctc
     3421 cgccggtaca ggtaacccgt tctttaccac cgactcagca gcttgcctgc gtggtatcga
     3481 aattgaagcc gatgtggtgc tgaaagcaac caaagttgac ggcgtgttta ctgctgatcc
     3541 ggcgaaagat ccaaccgcaa ccatgtacga gcaactgact tacagcgaag tgctggaaaa
     3601 agagctgaaa gtcatggacc tggcggcctt cacgcttgct cgtgaccata aattaccgat
     3661 tcgtgttttc aacatgaaca aaccgggtgc gctgcgccgt gtggtaatgg gtgaaaaaga
     3721 agggacttta atcacggaat aattcccgtg atggataaat aagggtaaga ttccgcgtaa
     3781 gtatcgcggg ggatcttacc cgtaatatgt ttaatcaggg ctatacttag cacacttcca
     3841 ctgtgtgtga ctgtctggtc tgactgagac aagttttcaa ggattcgtaa cgtgattagc
     3901 gatatcagaa aagatgctga agtacgcatg gataaatgcg tagaagcgtt caaaacccaa
     3961 atcagcaaaa tacgcacggg tcgtgcttct cccagcctgc tggatggcat tgtcgtggaa
     4021 tattacggca cgccgacgcc gctgcgtcag ctggcaagcg taacggtaga agattcccgt
     4081 actctgaaaa tcaacgtgtt tgatcgttca atgtctccgg ccgttgaaaa agcgattatg
     4141 gcgtccgatc ttggcctgaa cccgaactct gcgggtagcg acatccgtgt tccgctgccg
     4201 ccgctgacgg aagaacgtcg taaagatctg accaaaatcg ttcgtggtga agcagaacaa
     4261 gcgcgtgttg cagtacgtaa cgtgcgtcgt gacgcgaacg acaaagtgaa agcactgttg
     4321 aaagataaag agatcagcga agacgacgat cgccgttctc aggacgatgt acagaaactg
     4381 actgatgctg caatcaagaa aattgaagcg gcgctggcag acaaagaagc agaactgatg
     4441 cagttctgat ttcttgaacg acaaaaacgc cgctcagtag atccttgcgg atcggctggc
     4501 ggcgttttgc tttttattct gtctcaactc tggatgtttc atgaagcaac tcaccattct
     4561 gggctcgacc ggctcgattg gttgcagcac gctggacgtg gtgcgccata atcccgaaca
     4621 tttccgcgta gttgcgctgg tggccggcaa aaatgtcact cgcatggtag aacagtgcct
     4681 ggaattctct ccccgctatg ccgtaatgga cgatgaagcg agtgcgaaac ttcttaaaac
     4741 gatgctacag caacagggga gccgcaccga agtcttaagt gggcaacaag ccgcttgcga
     4801 tatggcagcg cttaaggatg ttgatcaggt gatggcagcc attgttggcg ctgctggact
     4861 gttacctacg cttgctgcga tccgcgcggg taaaaccatt ttgctggcca ataaagaatc
     4921 actggttacc tgcggacgtc tgtttatgga cgccgtaaag cagagcaaag cgcaattgtt
     4981 accggtcgat agcgaacata acgccatttt tcagagttta ccgcaaccta tccagcataa
     5041 tctgggatac gctgaccttg agcaaaatgg cgtggtgtcc attttactta ccgggtctgg
     5101 tggccctttc cgtgagacgc cattgcgcga tttggcaaca atgacgcccg atcaagcctg
     5161 ccgtcatccg aactggtcga tgggacgtaa aatttccgtc gattcggcta ccatgatgaa
     5221 caaaggtctg gaatacattg aagcgcgttg gctgtttaac gccagcgcca gccagatgga
     5281 agtgctgatt cacccgcagt cagtgattca ctcaatggtg cgctaccagg acggcagtgt
     5341 tctggcgcag ctgggtgaac cggatatgcg tacgccaatt gctcacacca tggcatggcc
     5401 gaatcgcgtg aactctggcg tgaagccgct tgatttttgc aaactaagtg cgttgacatt
     5461 tgccgcaccg gattatgatc gttatccatg tctgaaactg gcgatggagg cgtttgaaca
     5521 aggccaggca gcgacgacag cattgaatgc cgcaaatgaa atcaccgtgg ctgcttttct
     5581 tgcgcaacaa atccgcttta cggatatcgc tgcgttgaat ttatccgtac tggaaaaaat
     5641 ggatatgcgc gaaccacaat gtgtggatga tgtgttatct gttgatgcga acgcgcgtga
     5701 agtcgccaga aaagaggtga tgcgtctcgc aagctgagga taatccggct acagagagtc
     5761 gcgctatttg ttagcgtagg gcttcagtga tatagtctgc gccatctgat cgtaagtagt
     5821 tggctttata aggtcaggta tgccgtggtt ttacacggct tttttttgta taggcttcag
     5881 tattcctgag taccgtaaac cctgtcaggg aataagaaac gcgtgatgtt gtctgctact
     5941 caaccactta gcgaaaaatt gccagcgcat ggctgtcgtc atgttgcgat cattatggac
     6001 ggcaatggtc gctgggcaaa aaagcaaggg aagattcgtg cctttgggca taaagccggg
     6061 gcaaaatccg tccgccgggc tgtctctttt gcggccaaca acggtattga ggcgttaacg
     6121 ctgtatgcct ttagtagtga aaactggaac cgaccagcgc aggaagtcag tgcgttaatg
     6181 gaactgtttg tgtgggcgct agatagcgaa gtaaaaagtc tgcaccgaca taacgtgcgt
     6241 ctgcgtatta ttggcgatac cagtcgcttt aactcgcgtt tgcaagaacg tattcgtaaa
     6301 tctgaagcgc taacagccgg gaataccggt ctgacgctga atattgcggc gaactacggt
     6361 ggacgttggg atatagtcca gggagtcagg caactggctg aaaaggtgca gcaaggaaac
     6421 ctgcaaccag atcagataga tgaagagatg ctaaaccagc atgtctgtat gcatgaactg
     6481 gcccctgtag atttagtaat taggactggg ggggagcatc gcattagtaa ctttttgctt
     6541 tggcaaattg cctatgccga actttacttt acagatgttc tctggcccga tttcgatgaa
     6601 caagactttg aaggggcgtt aaatgccttt gctaatcgag agcgtcgttt cggcggcacc
     6661 gagcccggtg atgaaacagc ctgatggggg tcgcttttgc tgaagtatcg cctgatatct
     6721 gcttttgtgt taatacccgt cgtcatcgcg gcgttgtttc tgttgccgcc ggtggggttc
     6781 gccattgtaa cgctggtggt ctgtatgctg gcagcgtggg aatggggaca gcttagcggt
     6841 tttaccactc gttcgcagcg agtatggttg gcggtgttat gcgggttatt gttggcgctg
     6901 atgctttttc tgttgccgga atatcaccga aatattcatc aaccgctggt tgaaatctca
     6961 ctttgggctt cgctgggttg gtggattgtc gcgctattgc tggtgctgtt ttacccaggt
     7021 tccgcagcaa tctggcgtaa ctctaaaaca ttgcgcatta tttttggcgt gctaaccatt
     7081 gttcccttct tctggggcat gctggcgtta cgggcctggc actacgacga gaatcattac
     7141 agtggcgcaa tatggctgct ctatgtcatg atcctggtat ggggcgctga ctctggcgca
     7201 tatatgtttg gcaaattgtt tggtaaacat aaactggcac cgaaggtttc tccgggtaaa
     7261 acctggcaag gctttatcgg tggactcgtg accgcagcgg taatctcatg gggttatggc
     7321 atgtgggtga atctcgacgt cgctcccgtc accttactca tttgctctat tgtcgcagcg
     7381 ttagcctcag tgctcggcga tctgaccgaa agtatgttta agcgtgaagc gggaattaag
     7441 gacagcggtc atttaattcc aggacacggt ggtattttag atcgtattga tagcctgacg
     7501 gctgcggtac cggtctttgc ttgcttgttg ttactggtat tcaggacgct ttaacggaag
     7561 gtaatatgct gagttttctc tgggatttgg cttcgttcat cgttgcactg ggtgtactta
     7621 tcaccgtgca tgaatttggt catttctggg ttgcccggcg ttgtggtgtt cgcgttgagc
     7681 gtttctcaat agggtttggt aaggcgctct ggcggcgaac tgataagctc ggcaccgaat
     7741 atgttatcgc cctgatcccg ttgggcggtt atgtcaaaat gctggatgag cgcgcagaac
     7801 cggtcgttcc ggaactccgc caccatgcct tcaataataa atctgtcggc caacgagcgg
     7861 cgattattgc cgcaggtcca gttgcaaact tcatttttgc tatctttgcc tactggctgg
     7921 tttttattat tggtgtgcct ggcgtacgtc cggtggttgg tgaaatagca gccaattcga
     7981 tagctgcgga agcacaaatt gcaccaggta cggaactaaa agccgtagat ggtatcgaaa
     8041 cgcctgattg ggatgccgtg cgtttgcagt tggtcgataa aattggcgat gaaagcacca
     8101 ccattacggt agcgccattt ggcagcgacc aacggcggga tgtaaagctc gatttacgtc
     8161 actgggcgtt tgagcctgat aaagaagatc cggtatcttc gttggggatt cgtcctcgtg
     8221 ggccgcaaat tgaacctgta ctggaaaatg tgcagccaaa ctcggcggca agcaaggcag
     8281 gtttgcaagc aggcgacagg atcgttaaag tcgatggtca gcccttaacg cagtgggtga
     8341 cctttgtgat gcttgtccgg gataacccgg gtaaatcctt agcgttagaa atcgaaagac
     8401 aggggagtcc cttgtctttg acattaatcc cggagagtaa accgggtaat ggtaaagcga
     8461 ttggttttgt cggtattgag ccgaaagtca ttcctttgcc tgatgagtat aaagttgtac
     8521 gccagtatgg gccgttcaac gctatcgtcg aagccacgga caaaacgtgg cagttgatga
     8581 agctgacggt cagtatgctg ggaaaattga tcaccggtga tgtgaaactg aacaacctca
     8641 gtgggccgat ctctatcgcc aagggggctg ggatgacagc ggaactcggg gtagtttatt
     8701 acctgccgtt tcttgcgctt attagcgtga acttagggat aattaacctg tttccgttgc
     8761 ccgtacttga cggggggcat ctgctgttcc ttgcgatcga aaagatcaag ggcggaccgg
     8821 tatccgagcg ggttcaagac ttttgttatc gcattggctc gattctgctg gtgctgttaa
     8881 tggggcttgc acttttcaat gatttctctc ggttatgaga gttagttagg aagaacgcat
     8941 aataacgatg gcgatgaaaa agttgctcat agcgtcgctg ctgtttagca gcgccaccgt
     9001 atacggtgct gaagggttcg tagtgaaaga tattcatttc gaaggccttc agcgtgtcgc
     9061 cgttggtgcg gccctcctca gtatgccggt gcgcacaggc gacacggtta atgatgaaga
     9121 tatcagtaat accattcgcg ctctgtttgc taccggcaac tttgaggatg ttcgcgtcct
     9181 tcgtgatggt gatacccttc tggttcaggt aaaagaacgt ccgaccattg ccagcattac
     9241 tttctccggt aacaaatcgg tgaaagatga catgctgaag caaaacctcg aggcttctgg
     9301 tgtgcgtgtg ggcgaatccc tcgatcgcac caccattgcc gatatcgaga aaggtctgga
     9361 agacttctac tacagcgtcg gtaaatatag cgccagcgtt aaagctgtcg tgaccccgct
     9421 gccgcgcaac cgtgttgacc taaaactggt gttccaggaa ggtgtgtcag ctgaaatcca
     9481 gcaaattaac attgttggta accatgcttt caccaccgat gaactgatct ctcatttcca
     9541 actgcgtgac gaagtgccgt ggtggaacgt ggtaggcgat cgtaaatacc agaaacagaa
     9601 actggcgggc gaccttgaaa ccctgcgcag ttactatctg gatcgcggtt atgcccgttt
     9661 caacatcgat tctacccagg tcagtctgac gccagataaa aaaggtattt acgtcacggt
     9721 gaacatcacc gaaggcgatc agtacaagct ttctggcgtt gaagtgagcg gcaatcttgc
     9781 cgggcactcc gctgaaattg agcaactgac taagatcgag ccgggcgagc tgtataacgg
     9841 caccaaagtg accaaaatgg aagatgacat taaaaagctt cttggtcgct atggttatgc
     9901 ctatccgcgc gtacagtcga tgcctgaaat taacgatgcc gacaaaaccg ttaaattacg
     9961 cgtgaacgtt gatgcgggta accgtttcta tgtgcgtaag atccgttttg aaggtaacga
    10021 tacctcgaaa gatgctgtcc tgcgtcgcga aatgcgtcag atggaaggtg catggctggg
    10081 gagcgatctg gtcgatcagg gtaaggagcg tctgaaccgt ctgggcttct ttgaaactgt
    10141 cgataccgat acccaacgtg ttccggggag cccggatcag gttgatgtag tttacaaggt
    10201 gaaagaacgt aacaccggta gcttcaactt cgggattggt tacggtactg aaagtggcgt
    10261 gagcttccag gctggtgtgc aacaggataa ctggttaggt acgggttatg ctgttggtat
    10321 caacgggacc aaaaacgatt accagaccta tgctgaactg tcggtaacca acccgtactt
    10381 caccgtagat ggcgtaagcc tcggtggtcg tctcttctat aatgacttcc aggcagatga
    10441 cgccgacctg tccgactata ccaacaagag ttatggtaca gacgtgacgt tgggcttccc
    10501 gatcaacgaa tataactcgc tgcgtgcagg tctgggttat gtacataact ccctgtccaa
    10561 catgcagcct caggttgcga tgtggcgtta tctgtactct atgggtgaac atccgagcac
    10621 ctctgatcag gataacagct tcaaaacgga cgacttcacg ttcaactatg gttggaccta
    10681 taacaagctt gaccgtggtt acttcccgac agatggttca cgtgtcaacc tgaccggtaa
    10741 agtgaccatt ccgggatcgg ataacgaata ctacaaagtg acgttagaca cggcgactta
    10801 tgtgccgatt gatgacgatc acaaatgggt tgttctgggt cgtacccgtt ggggttatgg
    10861 tgatggttta ggcggcaaag agatgccgtt ctatgagaac ttctatgccg gtggttccag
    10921 caccgtgcgt ggcttccagt ccaataccat tggtccgaaa gcagtttact tcccgcatca
    10981 ggccagtaat tatgatccgg actatgatta cgaatgtgcg actcaggacg gcgcgaaaga
    11041 tctgtgtaaa tcggatgatg ctgtaggcgg taacgccatg gcggttgcca gcctcgagtt
    11101 catcaccccg acgccgttta ttagcgataa gtatgctaac tcggttcgta cttccttctt
    11161 ctgggatatg ggtaccgttt gggatacaaa ctgggattcc agccaatatt ctggatatcc
    11221 ggactatagt gatccaagca atatccgtat gtctgcgggt atcgcattac aatggatgtc
    11281 cccattgggg ccgttggtgt tctcctacgc ccagccgttc aaaaagtacg atggagacaa
    11341 ggcagaacag ttccagttta acatcggtaa aacctggtaa gtgttctcca caaaggaatg
    11401 tagtggtagt gtagcgatga ctttaggcga tcaatataag atcgccgggc cacgcaaaga
    11461 actgcaccct ccggtgcaaa tgggatggta aggagtttat tgtgaaaaag tggttattag
    11521 ctgcaggtct cggtttagca ctggcaactt ctgctcaggc ggctgacaaa attgcaatcg
    11581 tcaatatggg cagcctgttc cagcaggtag cgcagaaaac cggtgtttct aacacgctgg
    11641 aaaacgagtt caaaggccgt gccagcgaac tgcagcgtat ggaaaccgat ctgcaggcta
    11701 aaatgaaaaa gctgcagtcc atgaaagcgg gcagcgatcg cactaagctg gaaaaagacg
    11761 tgatggctca gcgccagact tttgctcaga aagcgcaggc ttttgagcag gatcgcgcac
    11821 gtcgttccaa cgaagaacgc ggcaaactgg ttactcgtat ccagactgct gtgaaatccg
    11881 ttgccaacag ccaggatatc gatctggttg ttgatgcaaa cgccgttgct tacaacagca
    11941 gcgatgtaaa agacatcact gccgacgtac tgaaacaggt taaataagta atgccttcaa
    12001 ttcgactggc tgatttagcg cagcagttgg atgcagaact acacggtgat ggcgatatcg
    12061 tcatcaccgg cgttgcgtcc atgcaatctg cacaaacagg tcacattacg ttcatggtta
    12121 acccaaaata ccgtgagcat ttaggcttgt gccaggcgtc cgcggttgtc atgacccagg
    12181 acgatcttcc tttcgcgaaa agtgccgcgc tggtagtgaa gaatccctac ctgacttacg
    12241 cgcgcatggc gcaaatttta gataccacgc cgcagcccgc gcagaacatt gcacccagtg
    12301 cggtgattga cgcgacggcg aagctgggta acaacgtatc gattggcgct aacgcggtga
    12361 ttgagtccgg cgttgaactg ggcgataacg tgattatcgg tgccggttgc ttcgtaggta
    12421 aaaacagcaa aatcggtgca ggttcgcgtc tctgggcgaa cgtaaccatt taccatgaga
    12481 tccagatcgg tcagaattgc ctgatccagt ccggaacagt ggtaggcgca gacggctttg
    12541 gttatgccaa cgatcgtggt aactgggtga agatcccaca gattggtcgg gtaattattg
    12601 gcgatcgcgt ggagatcggt gcctgcacta ctattgatcg tggcgcgctg gatgacactg
    12661 ttattggcaa tggtgtgatc attgataacc agtgccagat tgcacataac gtcgtgattg
    12721 gcgacaatac ggcagttgcc ggtggcgtca ttatggcggg cagcctgaaa attggtcgtt
    12781 actgcatgat cggcggagcc agcgtaatca acgggcatat ggaaatatgc gacaaagtga
    12841 cggttacggg catgggtatg gtgatgcgtc ccatcactga accaggcgtc tattcctcag
    12901 gcattccgct gcaacccaac aaagtctggc gcaaaaccgc tgcactggtg atgaacattg
    12961 atgacatgag caagcgtctg aaatcgcttg agcgcaaggt taatcaacaa gactaacgtt
    13021 ccatcttttg ttcgccaaac tttacggcct gtctcattct tacgattgcg gcaggccgtg
    13081 ttattattgt cgtttcttat attttgacag gaagagtatc ttgactacta acactcatac
    13141 tctgcagatt gaagagattt tagaacttct gccgcaccgt ttcccgttct tactggtgga
    13201 tcgcgtgctg gattttgaag aaggtcgttt tctgcgcgca gtaaaaaatg tctctgtcaa
    13261 tgagccattc ttccagggcc atttccctgg aaaaccgatt ttcccgggtg tgctgattct
    13321 ggaagcaatg gcacaggcaa caggtattct ggcgtttaaa agcgtaggaa aactggaacc
    13381 gggtgagctg tactacttcg ccggtattga cgaagcgcgc tttaagcgcc cggtcgtgcc
    13441 tggcgatcaa atgatcatgg aagtcacttt cgaaaaaacg cgccgcggcc tgacccgttt
    13501 taaaggggtt gctctggtcg acggtaaagt agtttgcgaa gcaacgatga tgtgtgctcg
    13561 tagccgggag gcctgatacg tgattgataa atccgccttt gtgcatccaa ccgccattgt
    13621 ggaagagggc gcgtcgattg gcgcgaacgc tcacattggt cctttttgta tcgttggacc
    13681 ccatgtcgaa attggtgagg gtaccgtact gaaatctcac gttgtcgtga atggtcatac
    13741 taaaattggc cgcgataatg agatttatca gttcgcctcc atcggcgaag ttaaccagga
    13801 tctgaaatat gctggcgaac cgacccgcgt ggaaatcggc gatcgtaacc gcattcgcga
    13861 aagcgtcacc attcatcgtg gcacagtcca gggcggtgga ttgacgaagg tgggcagcga
    13921 caacttactg atgatcaacg cgcacattgc gcacgattgt acggtaggta accgctgcat
    13981 cctcgccaac aacgcaacgc tggcgggtca cgtatcggtt gacgacttcg cgatcatcgg
    14041 cggcatgacc gcagtccatc agttctgcat cattggtgcg catgtgatgg ttggcggctg
    14101 ctccggtgtg gcgcaggacg tccctcctta tgtcattgcg cagggtaacc acgcaacgcc
    14161 gttcggtgtc aatatcgaag ggctgaagcg ccgcggattc agccgtgagg cgattaccgc
    14221 tatccgcaat gcgtataagc tgatttatcg tagcggtaag acgctcgatg aagtgaaacc
    14281 ggaaattgct gaactggcgg aaacatatcc ggaagtgaaa gcctttaccg atttctttgc
    14341 acgctcaacg cgcggtctga ttcgttaatg actgaacagc gtccattaac gattgccctg
    14401 gtcgccggag aaacctccgg cgatatcctg ggggccggtt taatccgcgc tctgaaagaa
    14461 cgtgtgccca acgcccgctt tgttggtgtt gccgggccac gaatgcaggc tgaaggctgc
    14521 gaagcctggt acgaaatgga agaactggca gtgatgggca ttgttgaagt gctcggtcgt
    14581 ctgcgtcgct tactacatat tcgtgccgat ctgacaaagc gttttggcga actgaagcca
    14641 gatgtttttg ttggtattga tgcgcctgac ttcaatatta ctcttgaagg taacctcaaa
    14701 aagcagggta tcaaaaccat tcattacgtc agtccgtccg tctgggcgtg gcgacagaaa
    14761 cgcgttttca aaataggcag agccaccgat ctggtgctcg catttctgcc tttcgaaaaa
    14821 gcgttttatg acaaatacaa cgtaccgtgc cgctttatcg gtcataccat ggctgatgcc
    14881 atgccattag atccagataa aaatggtgcc cgtgatgtgc tggggatccc ttacgatgcc
    14941 cactgtctgg cattgttgcc gggcagccgt ggtgcagaag tcgaaatgct tagtgccgat
    15001 ttcctgaaaa cggcccagct tttgcgccag acatatccgg atctcgaaat cgtggtgccg
    15061 ctggtgaatg ccaaacgccg tgagcagttt gaacgcatca aagctgcagt cgcgccagac
    15121 ctgtcggttc atttgctgga tggaatgggc cgtgaggcga tggtcgccag tgatgcggcg
    15181 ctactggcgt cgggtacggc agcactggag tgtatgctgg ctaaatgccc gatggtagtg
    15241 ggatatcgca tgaagccttt caccttctgg ctggcgaagc gactggtgaa aactgattat
    15301 gtctcgctgc caaatctgct ggcgggcaga gagttagtca aagagttatt gcaggaagag
    15361 tgtgagccgc aaaaattggc tgcggcgctg ttaccgctgt tggcgaacgg gaaaaccagc
    15421 catgcgatgc acgacacctt ccgcgagctg catcagcaga tccgctgcaa tgccgatgag
    15481 caggcggcac aagccgttct ggagttagca caatgatcga atttgtctat ccgcacacgc
    15541 agctggttgc gggtgtggat gaagtcggac gcgggccgtt agttggcgcg gtcgtcaccg
    15601 ctgcggtgat ccttgacccg gcgcgcccga ttgccgggct gaatgattcc aaaaagctga
    15661 gcgaaaaacg ccgtctggcg ctctgtgaag agatcaaaga gaaagcgttg agctggagtc
    15721 tgggccgcgc ggaacctcac gaaatcgacg aactgaatat tttacatgcg accatgctgg
    15781 cgatgcagcg tgccgtcgct ggactgcata ttgcgccgga atatgtgttg attgatggta
    15841 accgctgccc gaaattaccg atgccttcga tggctgtggt gaaaggcgat agccgcgtac
    15901 cggaaatcag tgccgcgtct atcctggcga aagtgacgcg tgacgccgaa atggcggcgc
    15961 tggatattgt tttcccgcaa tatggttttg cccaacacaa agggtatcca accgcttttc
    16021 atctggaaaa actggctgaa cacggcgcga ccgaacacca tcggcgcagc tttgggcctg
    16081 tcaaacgcgc actgggactt gcgtcctgat tcttgtgtcg agattaagta aaccggaatc
    16141 tgaagatgtc tgaaccacgt ttcgtacacc tgcgggtgca cagtgactac tcgatgatcg
    16201 atggcctggc caaaaccgca ccgctggtaa aaaaggcggc agcgttgggt atgccagcac
    16261 tggcgatcac cgatttcacc aacctttgcg gtctggtgaa gttctacgga gcgggacatg
    16321 gcgcagggat taagcccatc gtcggggcgg attttaacgt ccagtgcgac ctgctgggtg
    16381 atgagttaac tcacctgacg gtgctggcgg cgaacaatac cggctatcag aatctgacgt
    16441 tgctgatctc aaaagcgtat cagcgcgggt acggtgccgc cgggccgatc atcgatcgcg
    16501 actggcttat cgaattaaac gaagggttga tccttctttc cggcgggcgc atgggcgacg
    16561 ttggacgcag tcttttgcgt ggtaacagcg cgctggtaga tgagtgtgtc gcgttttatg
    16621 aagaacactt cccggatcgc tattttctcg agctgatccg caccggcagg ccggacgaag
    16681 aaagctatct gcacgctgcg gtggaactgg cggaatcacg cggtttgccc gttgtggcga
    16741 ccaacgacgt gcgctttatc gacagcagcg actttgacgc acacgaaatc cgcgtcgcga
    16801 tccacgacgg ctttaccctc gacgatccta aacgcccgcg taactattcg ccgcagcaat
    16861 atatgcgtag cgaagaggag atgtgcgagc tttttgccga cattcccgaa gcccttgcca
    16921 acaccgttga gatagccaaa cgttgtaacg taactgtgcg tctgggtgaa tacttcttgc
    16981 cgcaattccc gaccggggac atgagtaccg aagattatct ggtcaagcgt gcaaaagaag
    17041 gcctggaaga gcgtctggca tttttattcc ctgacgagga agaacgtctt aagcgtcgtc
    17101 cggagtatga cgaacgtctg gatactgaac ttcaggttat caaccagatg ggcttcccgg
    17161 gttacttcct catcgttatg gaatttatcc agtggtcgaa agataacggt gtaccggtag
    17221 ggccaggccg tggttctggt gcagggtcac tggtggccta cgcgttaaaa atcaccgatc
    17281 tcgatccgct ggaatttgac ctgctgttcg aacgtttcct taacccggaa cgtgtctcca
    17341 tgcctgactt cgacgttgac ttctgtatgg agaaacgtga ccaggttatc gaacatgtgg
    17401 cggacatgta cggtcgcgat gcggtatcgc agattatcac cttcggtacg atggcggcga
    17461 aagcggtgat ccgcgacgta ggccgtgtat tggggcatcc gtacggattt gtcgatcgta
    17521 tctcgaaact gatcccgccc gatccgggta tgacgctggc gaaagcgttt gaagccgagc
    17581 cgcagctgcc ggaaatctac gaagcggatg aagaagttaa ggcgctgatc gacatggcgc
    17641 gcaaactgga aggggtcacc cgtaacgccg gtaagcacgc cggtggggtg gttatcgcgc
    17701 cgaccaaaat tactgatttt gcgccgcttt attgcgatga agagggcaaa catccggtca
    17761 cccagtttga taaaagcgac gttgaatacg ccgggctggt gaagttcgac ttcctcggtt
    17821 tgcgtacgct caccatcatc aactgggcgc tggagatgat caacaagcgg cgggcgaaga
    17881 atggcgagcc cccgctggat atcgccgcga tcccgctgga tgacaagaaa agcttcgaca
    17941 tgctgcaacg ctcggaaacc acggcggtat tccagcttga atcgcgcggc atgaaagacc
    18001 tgatcaagcg tctgcaacct gactgcttcg aagatatgat cgcactggtg gcactgttcc
    18061 gccccggccc gttgcaatca gggatggtgg ataactttat cgaccgtaaa catggtcgcg
    18121 aagagatctc ctatccggac gtgcagtggc agcatgaaag cctgaaaccg gtactggagc
    18181 caacctacgg catcatcctg tatcaggaac aggtcatgca gattgcccag gtgctttctg
    18241 gttataccct cggtggcgcg gatatgctgc gtcgtgcgat gggtaagaaa aagccggaag
    18301 agatggctaa gcagcgttct gtatttgctg aaggtgcaga aaagaacgga atcaacgccg
    18361 aactggcgat gaaaatcttc gacctggtgg agaaattcgc gggttacgga tttaacaaat
    18421 cgcactcggc ggcctatgct ttggtgtcat atcaaacgtt atggctgaag gcacattatc
    18481 cggcagagtt tatggcggcg gtaatgaccg ccgatatgga caacaccgag aaggtggtgg
    18541 gcctggtgga tgagtgctgg cggatggggc tgaaaatcct gccaccagat ataaactccg
    18601 gtctttacca tttccacgtc aacgacgacg gcgaaatcgt gtatggtatt ggcgcgatca
    18661 aaggggtagg tgaaggcccg attgaggcca tcatcgaagc ccgtaataaa ggcggctact
    18721 tccgcgaact gtttgatctc tgcgcccgta ccgacaccaa aaagttaaac cggcgggtgc
    18781 tggaaaaact gatcatgtcc ggggcgtttg accgtcttgg gccacaccgc gcggcgctga
    18841 tgaactcgct gggcgatgcg ttaaaagcgg cagatcaaca cgcgaaagcg gaagctatcg
    18901 gtcaggccga tatgttcggc gtgctggccg aagagccgga acaaattgaa caatcctacg
    18961 ccagctgcca accgtggccg gagcaggtgg tgttagatgg ggaacgtgaa acgttaggtc
    19021 tgtacctcac gggacaccct atcaaccagt atttaaaaga gattgagcgt tatgtcggag
    19081 gcgtaaggct gaaagacatg cacccgacag aacgtggtaa agtcatcacg gctgcggggc
    19141 tcgttgttgc cgcgcgggtt atggtcacca agcgcggcaa tcgtatcggt atctgcacgc
    19201 tggatgaccg ttccgggcgg ctggaagtga tgttgtttac tgacgccctg gataaatacc
    19261 agcaattgct ggaaaaagac cgcatactta tcgtcagcgg acaggtcagc tttgatgact
    19321 tcagcggtgg gcttaaaatg actgctcgcg aagtgatgga tattgacgaa gcccgggaaa
    19381 aatatgctcg cgggcttgct atctcgctga cggacaggca aattgatgac cagcttttaa
    19441 accgactccg tcagtctctg gaaccccacc gctctgggac aattccagta catctctact
    19501 atcagagggc ggatgcacgc gcgcgattgc gttttggcgc gacgtggcgt gtctctccga
    19561 gcgatcgttt attaaacgat ctccgtggcc tcattggttc ggagcaggtg gaactggagt
    19621 ttgactaata caggaatact atgagtctga atttccttga ttttgaacag ccgattgcag
    19681 agctggaagc gaaaatcgat tctctgactg cggttagccg tcaggatgag aaactggata
    19741 ttaacatcga tgaagaagtg catcgtctgc gtgaaaaaag cgtagaactg acgcgtaaaa
    19801 tcttcgccga tctcggtgca tggcagattg cgcaactggc acgccatcca cagcgtcctt
    19861 ataccctgga ttacgttcgc ctggcatttg atgaatttga cgaactggct ggcgaccgcg
    19921 cgtatgcaga cgataaagct atcgtcggtg gtatcgcccg tctcgatggt cgtccggtga
    19981 tgatcattgg tcatcaaaaa ggtcgtgaaa ccaaagaaaa aattcgccgt aactttggta
    20041 tgccagcgcc agaaggttac cgcaaagcac tgcgtctgat gcaaatggct gaacgtttta
    20101 agatgcctat catcaccttt atcgacaccc cgggggcata tccgggcgtg ggcgcagaag
    20161 aacgtggtca gtcggaagcc attgcacgca acctgcgtga aatgtctcgc ctcggcgtac
    20221 cggtagtttg tacggttatc ggtgaaggtg gttctggtgg tgcgctggcg attggcgtgg
    20281 gcgataaagt gaatatgctg caatacagca cctattccgt tatctcgccg gaaggttgtg
    20341 cgtccattct gtggaagagc gctgacaaag cgccgctggc ggctgaagcg atgggtatca
    20401 tcgctccgcg tctgaaagag ctgaaactga tcgactccat catcccggaa ccgctgggcg
    20461 gtgctcaccg taacccggaa gcgatggcgg cgtctctgaa agcgcagctg ctggcggatc
    20521 tggccgatct cgacgtgtta agcactgaag atttaaaaaa tcgtcgttat cagcgcctga
    20581 tgagctacgg ctacgcgtaa tcggcaaatg ttctgaaaag ggtcacttcg gtggcccttt
    20641 tttatcgcca cggtttgagc aggctatgat taaggaagga ttttccagga ggaacacatg
    20701 aacatcattg ccattatggg accgcatggc gtcttttata aagatgagcc catcaaagaa
    20761 ctggagtcgg cgctggtggc gcaaggcttt cagattatct ggccacaaaa cagcgttgat
    20821 ttgctgaagt ttatcgaaca taacccacga atttgcggcg tgatttttga ctgggatgag
    20881 tacagtctcg atttatgtag cgatatcaat caacttaatg aatatctccc gctttatgcc
    20941 ttcatcaaca cccactcgac gatggatgtc agcgtgcagg atatgcggat ggcgctctgg
    21001 ttttttgaat atgcgctggg gcaggcggaa gatatcgcca ttcgtatgcg tcagtacacc
    21061 aacgaatatc ttgataacat tacgccgccg tttacgaaag ccttgtttac ctacgtcaaa
    21121 gagcggaagt acaccttttg tacgccgggg catatgggcg gtaccgcata tcaaaaaagc
    21181 ccggttggct gtctgtttta tgattttttc ggcgggaata ccctcaaggc ggacgtctct
    21241 atttcggtca ccgagcttgg ttcgttgctc gaccacaccg ggccacacct ggaagcggaa
    21301 gagtacatcg cgcggacgtt tggcgcggaa cagagttata tcgttactaa tggaacatcg
    21361 acgtcgaaca aaattgtggg tatgtacgcc gcgccatccg gcagtacgct gttgatcgac
    21421 cgcaattgtc ataaatcgct ggcgcatctg ttgatgatga acgatgtagt gccagtctgg
    21481 ctgaaaccga cgcgtaatgc gttggggatt ctgggtggga tcccgcgcgg tgaatttact
    21541 cgcgacagca tcgaagagaa agtcgctgcc accacgcagg cacaatggcc ggttcatgcg
    21601 gtgatcacca actccaccta tgatggcttg ctctacaaca ccgactggat caaacagacg
    21661 ctggatgtcc cgtcgattca cttcgattct gcctgggtgc cgtacaccca ttttcatccg
    21721 atctaccagg gtaaaagtgg tatgagcggt gagcgtgttg cgggaaaagt gatcttcgaa
    21781 acgcagtcga cccacaaaat gctggcggcg ttgtcccagg cgtcgctgat ccacattaaa
    21841 ggcgagtatg acgaagaggc gtttaacgaa gcctttatga tgcataccac cacctcgccc
    21901 agttatccca ttgttgcttc ggttgagacg gcggcggcga tgctgcgtgg taatccgggc
    21961 aaacggctga ttaaccgttc agtagaacga gcgctgcatt ttcgcaaaga ggtccagcgg
    22021 ctgcgggaag agtctgacag ctggtttttc gatatctggc aaccgccgca ggtggatgaa
    22081 gccgaatgct ggcacgttgc gcctggcgaa cagtggcacg gctttagcga tgcggatgcc
    22141 aatcacatgt ttctcgatcc ggttaaagtc actattttga caccgggaat ggacgagcag
    22201 ggcaatatga gcgaggaggg gatcccggcg gcgctggtgg caaaattcct cgacgaacgt
    22261 gggatcgtag tagagaaaac cggcccttat aacctgctgt ttctctttag tattggcatc
    22321 gataaaacca aagcaatggg attattgcgt gggttgacgg aatttaagcg ctcttacgat
    22381 ctcaacctgc ggatcaaaaa tatgctgccc gatctctatg cagaagatcc cgatttctac
    22441 cgcaatatgc gtattcagga tctggcgcaa gggatccata agctgattcg taaacacgat
    22501 cttcccggtt tgatgttgcg ggcatttgat accttgccgg agatgatcat gacgccacat
    22561 caggcatggc agagacagat taaaggcgaa gtagaaacca ttgcgctgga acaactggtc
    22621 ggtagagtat cggcaaatat gatcctgcct tatccacccg gcgtaccgct gctgatgccg
    22681 ggagaaatgc ttaccgaaga gagccgcacg gtactcgatt ttctactgat gctttgttcc
    22741 gtagggcaac attaccccgg ttttgaaacg gatattcacg gcgcgaaaca ggacgaagac
    22801 ggcgtttacc gcgtacgagt cctaaaaatg gcgggataac ttgccagagc ggcttccggg
    22861 cgagtaacgt gctgttaaca aataaaggag acgttatgct gggtttaaaa caggttcacc
    22921 atattgcgat tattgcgacg gattatgcga tgagcaaagc tttctactgc gatattcttg
    22981 gtttcacgct gcaaagcgaa gtctatcgcg aagcgcgcga ctcgtggaaa ggggatttgg
    23041 cgcttaatgg gcaatatgtg attgagcttt tctcatttcc gttcccgccg gagcgcccca
    23101 gccgaccgga agcttgcggc ctgcgtcatc tggcttttag cgttgatgat atcgatgcgg
    23161 cagtggcgca ccttgaaagc cataacgtga agtgtgaagc catccgtgtc gatccataca
    23221 cgcaaaaacg cttcacgttc tttaacgatc cggacgggct gccgttggaa ctgtatgagc
    23281 agtaaggctt gtcatcgccg catttgcccg gtaacgtgcc gggcattgct actgtaaaat
    23341 cgcaccatca tgacactcac gctcaataga caacttctct cctcacgcca gattctggtg
    23401 gcctttagcg gcggccttga ttctactgtc ttactgcatc aactggtgca gtggcggacg
    23461 gaaaatccgg gcgtcactct gcgcgctatc catgtgcatc acggtttaag cgccaatgct
    23521 gatgcctggg tgaaacattg tgaaaacatc tgccaacagt ggcaggtgcc gctggtggtc
    23581 gaacgtgtgc agcttgcgca agaggggcta ggtattgagg cccaggcgcg gcaggcacgt
    23641 tatcaggcat ttgcccgtac cttgttgccc ggtgaagtgc tggttacagc gcaacatctc
    23701 gacgatcaat gtgaaacctt tctgctggcg ctaaaacgcg gtagcggccc tgccgggctt
    23761 tcggctatgg cggaagtttc ggagtttgcc ggaacacggc ttatccgccc gttgcttgcc
    23821 cgcacgcggg gggaactgga gcagtgggcg cgtcagtatg atttacgctg gattgaagac
    23881 gaaagtaatc aagacgattc ctacgatcgt aacttcttgc gcctgcgcgt agtgccgtta
    23941 ttgcagcagc gttggccgca ttttgccgaa gcgacggccc gcagcgccgc actttgcgcc
    24001 gaacaagaga gcctgctgga tgaactgctg gcggatgatt tagcgcactg ccaaacgcaa
    24061 cagggaacgt taaagattgc gccaatgctg gcaatgagcg atgcccgtcg cgcggcgatt
    24121 atccgccgct ggctggcagg gcagaatgca cctatgcctt cccgcgaggc gctggtgcgg
    24181 atctggcagg aagtggcgct ggcgcgggaa gatgcttccc cctgtttacg tttgggcgcg
    24241 tttgaaatcc gccgctatca gtcgcaactg tggtggatta aatccgttgc cgggcaaagc
    24301 gaaaccattg tgccgtggca gacgtggcta caaccgctgg aattaccggc ggggctggga
    24361 agtgtacagc ttactgcggg aggcgatatt cgccctccgc gtgcagacga agcggtcagc
    24421 gtgcgtttca aagcgccagg actgctgcat attgtcgggc gcaacggtgg acgtaagctg
    24481 aagaaaatct ggcaagagtt aggcgttccg ccgtggctac gtgacaccac gccactgctg
    24541 ttttatggcg aaacgctgat tgcggcggca ggggtatttg tgacgcaaga aggtgtggct
    24601 gtaggtgaga atggcgtcag ttttgtctgg cagaaaacgc ttagtcaagt gaaagccgga
    24661 taagacgcat caaacgtcgc atccggcgaa agtcaatcag gactcgctca ccaccaccgt
    24721 accgatttcc gggtggctaa agctggtaat tttatccaga cgcagctcgc gggttgcacc
    24781 agcggcctcg acgaccagat actccacatt tttgcgggag actaaatcgc tggccttcgc
    24841 ctgcaatttt tcgccatctt tcagctcaag tgtcagcatt aaatgatgct ggcaggcgag
    24901 ctcaagatta tcgtaatcat cacaattgat tggttgatac gtatcattca ttgacataat
    24961 cgctcaccag taagtttgcc gcagcgtatg ctgctttttc cctgacagcc tcagaaaggg
    25021 cgtcgtcggc agccatttca ttcagcactt tcaaaacgca gcccagcgcg tccggaacgt
    25081 atcctaagtc tccgctggcg atttccgcgt accgcttgcg tattaactca caatattttt
    25141 ccacatgccc tcctgtcagc actctgactt aaccgtggat gcaagtctaa gcctacgaag
    25201 ataaactctg tttcgcaagg tgactatacc acactcattt ctgcaatatc agcgccgcaa
    25261 ctgcacgtat tccgttacaa tggcctcctg attcgaaagg agttttctta tggcgcttaa
    25321 agcgacaatt tataaagcga cggttaatgt ggccgatctc gaccgcaacc agtttctcga
    25381 tgcctctctg acgttggcgc gccatccttc agaaacccag gagcgtatga tgctgcgcct
    25441 gctggcgtgg ctaaaatatg ccgatgaacg tctgcaattt acccgtggtt tgtgtgccga
    25501 tgatgagccg gaagcgtggc tgcgtaacga tcatttgggt attgatttgt ggattgagct
    25561 ggggctgccg gatgagcgac ggattaagaa agcctgcacc caggccgcag aagtggcgct
    25621 gtttgcctat aatagtcggg cggcgcaaat ctggtggcag caaaatcaga gcaaatgtgc
    25681 gcagtttgcc aatctttccg tctggtatct ggacgacgag cagctggcga aagtgagcgc
    25741 ctttgccgat cgtaccatga cgctgcaggc aacgattcag gatggtgtta tctggttatc
    25801 ggatgataag aataatctgg aagtgaactt aaccgtctgg caacaacctt catgattgtg
    25861 atttcccgac atgttgctat ccctgatggc gagtttgaga tcaccgccat tcgtgcgcag
    25921 ggcgcgggcg ggcagcatgt taataagacc tcaacggcta ttcatctgcg ttttgacatt
    25981 cgggcgtcca gcctgccaga gtattacaaa gagcgtctgc tcgccgccag ccatcatttg
    26041 atcagcagtg acggagtgat tgtcattaag gcacaggaat accgcagtca ggaactgaac
    26101 cgcgaagcgg cgctggcccg gctggtggca gtgattaaag atttaacaac agaacaaaaa
    26161 gcccgaagac ctacgcggcc cacccgtgca tcgaaagagc gcaggctggc atcgaaagca
    26221 caaaaatcaa gcgtgaaggc gatgcgcggc aaagtgcgca gcggtcggga gtaaaaagaa
    26281 ggaatggatg gtgaaaaaag cgatagtgac agcgatggct gtaatcagcc tttttactct
    26341 gatgggatgt aataatcggg ccgaagtcga tacgctttcc ccggcgcagg ctgccgaact
    26401 gaaaccgatg ccgcaaagtt ggcgcggcgt gctgccgtgt gctgattgcg aaggaatcga
    26461 aacctctctg ttcctcgaaa aagatggaac ctgggtgatg aatgaacgtt atctgggggc
    26521 acgtgaagag ccttcctctt tcgcttccta cggtacatgg gcgcgaactg ccgacaagct
    26581 ggtattaacc gacagcaaag gtgaaaagtc atattatcga gcgaaagggg atgcactgga
    26641 gatgctcgat cgtgaaggta atcccattga atcgcagttc aactacacgc tggaaccggc
    26701 aaaatcgagc atgccaatga cgccgatgac cctgcgtggc atgtatttct atatggctga
    26761 tgcggcgacc tttactgatt gcgcgactgg aaaacgtttt atggtggcga ataacgcaga
    26821 gctggagcgt ggctacctgg ctgcgcgcgg caacggcgaa aaaccggtgt tactgtcagt
    26881 agaaggtcac tttacgcttg aggctaatcc ggataccggt gcgccgacca aagtattagc
    26941 gcccgatacg gcaggtaaat tttacccgaa ccaggattgc agtagtttgg ggcagtaacc
    27001 cgtcttgagg cagaaacaaa tgaaatattg cctcatgcgc tgcgcttatc aggcctaaag
    27061 catacaatgc aatattttga attagcacga ttttgtaggc cggataaggc gttcacgccg
    27121 catccggcat tttgcgcacg aggctggctt ttatcactga gtcagtccaa caaagcgact
    27181 tgctttaata taaatccctg gcttcaggtg cccaatatac tgtaactgcg tttctggttt
    27241 aaatgcagag acatcaccac tacgcatatg catcagatcg gcagggctaa tccagcctga
    27301 ttgcgccagc gtaagcggat gcccggcttt ggcaaatgca tccgtgacaa attccgaaca
    27361 aaaccacgac tttttgtctc cttcgccaac gttacttaac tgcgctttcg ccaggccgct
    27421 gacgcactgt tggcgaaaat cctcggagaa cggattcagt gagcacatct ggcgagtcac
    27481 cataaatgga ataaattcga caatgccgcg atagttataa ccgctatctt taattttatt
    27541 ggcgaacgcg gtgatttctg tggcttgttg cggggtaagg tccgggactc gtaagacgaa
    27601 aagcttatca ctgtgcttca tggctttttt aagggaaaca atctggacgc cagcgcctgt
    27661 cgcttcggca acgttattat ttcccaaata gattgcaacg tgactcacag aggaagtgct
    27721 gaatacgcgg ataccaaatg aggttacccc aaggcttgag gagaaaagca aatcgccggg
    27781 tttgagatct ggttccgtta tttcttttat tgattgttcg gtgaaagagc tttgatgctg
    27841 gaatttaaca gcccatgttt tcgcctcggc atttaccgct gtggctgatg agtctggctg
    27901 gctgatatca acggtacagg ccgaaagtaa aagaaagcag gggagaagca ggcggcagta
    27961 cgcctttggt ttatccattt tatacaatcc atgtaaaaaa gggccccgaa attcaggacc
    28021 ctttctggca tcagccttta atctgtttca ccagataatc gacgatgtca ccagtcttaa
    28081 ttaactgttt ctcgccgtta cgacgatatt tatattcgat atcatcgttg tcgaggttac
    28141 ggtcgcccag cacaatagtg tgcggaatac cgatcagttc catatcagca aacatcacgc
    28201 ccggacgctc tttgcggtca tccagcagca cttcgatacc ttgtgcgcgc agttcgctgt
    28261 acagtttctc agcaagttcc tgtacgcgga aggatttgtg catgttcatt ggcagaatcg
    28321 ccacctggaa cggcgcgata gcgtcaggcc atacgatgcc gcgttcgtcg tagttctgct
    28381 caatcgccgc tgctaccaca cgcgttacgc cgataccgta gcaacccatc gtcaggattt
    28441 ggttacggcc atcttcaccc tgtacggagg ctttcagtgc ttcggagtac ttggtaccca
    28501 gctggaagat gtgaccgact tcgataccac gtttgatcag cagcgtaccc tgaccatccg
    28561 ggcttggatc gccagccacc acgttgcgga tatcagcaat ttccggggta gcgacatcgc
    28621 gatcccagtt gataccgaag tagtgtttac catcgatgtt agcaccagca gcgaaatcac
    28681 tcatcgccgc aacggtacgg tcaatcacca ccggaatcgg catgtttacc ggacccagtg
    28741 aacccggacc ggctttaacc acggcacgaa tttcttcttc ggtcgcaaaa gtcagcgggc
    28801 tggcaacctg cggcagtttt tctgctttaa cttcgttcag ctcgtggtca ccgcgcacca
    28861 gcagcgcaac cagcgggaag ctactgcctt caacggcttt aaccagcaga gtcttaaccg
    28921 ttttctcaat cggcagattg aactgttcaa ccagttccgc gatggttttc gcgttcggcg
    28981 tatcaaccag cgtcatttcc tgggtagcag cagcgcgcgg ttctttcggc gcgatagctt
    29041 ctgccagttc aatgttcgct gcgtagtcag aagtatcgga gaagaccaca tcgtcttcac
    29101 cgctctgcgc cagcacctga aattcgtgag aggcgctacc gccgatagaa ccggtatcgg
    29161 cctgtacggc gcggaaatcc agccccatgc ggctgaagat tttgctgtag gccgcataca
    29221 ttgcatcgta ggtttcctgc agggattcct gagaagtatg gaaagagtaa gcatctttca
    29281 tcaggaattc gcgggaacgc atgacgccaa aacgcggacg cacttcgtcg cggaacttgg
    29341 tctggatctg atagaagttc agcggcagtt gtttgtaaga gctcagctcg ttacgaatca
    29401 ggtcagtgat aacttcttca tgagttgggc cgagtacgaa cggacgctcg ccacggtcaa
    29461 caaaacgcag cagttccgga ccgtactgtt cccaacgacc actctcttgc cacaaatcgg
    29521 ctggctgaac caccggcatt aacacctcga tcgcaccggc gttgttcatc tcttcacgca
    29581 cgatgttttc gacttttttc agaacgcgca cgccggtcgg cagccaggta tataacccgg
    29641 aggccagctt gcggatcatc ccggcgcgca gcatcagctg atggctgatc acctcggcgt
    29701 cggcaggtgt ctccttgaga gtggagagca ggtattggct agtacgcatg ttgttacggt
    29761 tccagttgga aggtagaaca ggctcaaggc gagcctggga caaaaaaagt gatttagttt
    29821 accagtgcaa aagaaatgtc aaaagagaag ggcgtgaatt taacgcggtt ccagcgcaaa
    29881 gacttcaaaa cctgcgtcgg tgacgcgcca gcgaacgtta aaatcatgca accagacggc
    29941 ataggttttg cccgtttcct cacctttacg ataggccggg cgcgggtcct gcgccagtac
    30001 ttcgcggata aacagcgtta actgcggata acgcttctcc agcgtcaaaa gctgcttttc
    30061 gacctctgcg gtaaaacaaa ccgccatttc tgccgctggc gcactttgcg catagctggc
    30121 actggcatcg ggaagcgatt cagcaaaggg gagatacggt ttgatatcca ctaccggcgt
    30181 accatcgacc agatccagac tgccgagctt cagaatcacg ctgtctttat ggcaaacaac
    30241 ctctttcagc tctaccagcg acataccaat cgggttgggg cgaaaagtgg agcgcgtagc
    30301 gaaaacaccc attctggcat taccgccgag acgaggcgga cgcacagtcg gacgccagcc
    30361 gccttccatc gtttgatgaa agacgaaaag gatccataaa tggctgaatg cttccaggcc
    30421 gcgaacggcg tcggcctggt tgtagggagc aatgagatgt agttcgccgt tggcgctttt
    30481 taccagacct ggctggcgcg gaacggcgaa tttttcttta tagggcgagc gaataacgcc
    30541 tatttgctcg aactggaaac tgctcatttc gccgtgatgt taagcgcaga accgatacat
    30601 acagcctgac gatagcaacc tggcgtaccg ctggtgactt cgcagctatg cagtaatacc
    30661 gcattggctt tcattttcga ggcgttgatt tgcatccgct tacgtgcggt tggaatgctc
    30721 ggcggagagt cctgattaga ggcctggcaa gagtcgccac tgacttcacc gagatcgcgg
    30781 aacggtttgc cgactaattc ttctgcattg gtataaattc ggaccggcgt ggcgcgcggc
    30841 gctttcggtt ttgcaggctc cgctttcggc tggggtgcag tgctttgaac gggttcgaca
    30901 ggggatctgc ttaacatgga acagccgctt agcatgagtg ctactaaaca gatcggtaaa
    30961 gcacgcatag tatttcctca atgtatgatc aaaacgtcaa tattgaatca ggcgcttgta
    31021 aaaatgacaa gacgggcaag cgcccgtcct gaatgatatt acaaattgtg gaaacagcct
    31081 aaatattacc agcctttaac agcgccgccg ttaaacactt tgtttgctgc ttcgtaaact
    31141 tcgtcagact gataagcctg aacgaatttc ttcacgtttt cggcgtcttt gttgtcttca
    31201 cgcgttacga tcaggtttac gtacggggac tctttatctt cgacaaagat accgtctttc
    31261 gctggagtca ggccaatctg gctggcatag gtggtattga taactgccag agcgatttgc
    31321 gcgtcgtcca gagagcgcgg cagctgcggt gcttccagtt caacaatttt cagatttttt
    31381 gggttctcaa caacatcaag aacggtcggc agcaggccaa cgccatcttt cagtttgatc
    31441 aagcccactt tttgcagcag cagcagtgaa cgaccaaggt tagttgggtc gtttggcacg
    31501 gcaacctgcg aaccatcctg cagttcatcc agtgatttga ttttcttgga gtaaccagca
    31561 atcggataaa caaatgtgtt gcctactgcg accagtttgt agccacgatc tttcagttgc
    31621 tgatcaaggt acggtttatg ctggaaggcg ttggcgtcga tatcgccttt gctcaatgct
    31681 tcgtttggca gaacatagtc gttgaaggtt accagctcaa cgtccaggcc atatttgtct
    31741 ttcgcaactt tctgcgcgac ttctgcaacc tgctgttcgg caccaacaat cacgccgact
    31801 ttaatgtggt ttggatcttt ttcatcctga ccgcagccta ccagtgccag tgatccaatc
    31861 agggctccca ctgccgcaaa ggttttgaat ttgaacgcca taccttattc cttcttcaat
    31921 tatttatgtt gtgttgaacg ttacttgcga gtgacagccc ggacgatgcg gtcgcctgcg
    31981 aactgaatta aataaaccag aatgaccagc aataccagta ccgtattcat caccgtcgcg
    32041 ttgtagccga tgtagccata ctgatagcca atctgaccta aaccaccggc accgactgca
    32101 ccacccatcg cggaataacc gaccagggta atcagggtaa tagttgccgc attcaccaga
    32161 cccggcaacg cttccggtaa cagcacttta cggacgatct gcattggcgt ggcacccatt
    32221 gcgcgggagg cttcaattaa cccggttggg atctccagaa gagcgttctc gaccatacgg
    32281 gcaataaacg gtgctgcacc aacggttaac ggaacaatcg ctgcctgcaa tccaatcgat
    32341 gtaccgacaa taacgcgggt aaacggaatc atccatacca gcaagataat gaacgggatg
    32401 gaacggaaaa tgttcacaat cgcagaaatg gtacgataca acttcgcgtt agcaataatt
    32461 tgccccggac gcgtgacata aagcagaacg ccaaccggca gaccaatcac aaagccaaaa
    32521 aaaccggata cgaaggtcat tgccagcgtt tcccatacgc cacgaaccag cagccacatc
    32581 atcggctcag acataaccca gtacctctac ttttacatgg tgttcctgca gccaggcaat
    32641 ggcggcttgc gtatcttgtt gtgtgccgtg catttcagtc agcataatgc cgaacttaac
    32701 gccaccggcg taatccatct gcgcgctaat aatgttgttg ttgacgttga aacgacgcgc
    32761 ggtttcagaa agcagtgggg catcgaccga ttgaccggta aactccagac gcagcatcgg
    32821 cacgcagtca gtaaatggct ccgcttgcag acgttcctgg taatcttccg ggatatccag
    32881 atgcagggtc gactgaataa acttctgcgc cagcggcgtt ttcggatgcg agaacacttc
    32941 acttaccgtg tcctgctcga tcagttcgcc attgctgatg accgccacgc aatcacaaat
    33001 gcgcttcaca acgtccattt cgtgagtgat caacagaatc gtcaaaccca gacggcggtt
    33061 gatgtctttc agcagttcga gaatagaacg tgtcgttgcc gggtccagcg cgctggtggc
    33121 ttcatcacac agcaatactt tgggattgct ggctaatgca cgggcaatcg ccacacgttg
    33181 tttctgccca ccggaaagat tcgacgggta gctatcatgc ttatcgccaa gaccaaccaa
    33241 tgacagcaat tccgtcacgc gacgtttgat ctcgtctttc ggtgtgttgt ccagctccag
    33301 cggcagagcc acgttgccaa aaacagtacg cgaagagagc aggttaaaat gctggaaaat
    33361 cataccaatc tggcgacgag ctttggtcaa ctcggattct gacagcgtgg tcagttcctg
    33421 gccatcgacc agcacgctac cctcggttgg gcgctccagc aggtttacac aacgtataag
    33481 cgtactctta cccgcgcctg aggcaccgat aacgccataa atttgtccag ctggcacatg
    33541 caggctgacg ttgttcaacg cctggatggt gcgggtgccc tggtggaaca ctttggtgat
    33601 attcgaaagt tttatcattg attatttatt atcgtcatta agttagtcgt ggcatttcga
    33661 atgcctggaa cgggcaacgc cgtcaatgaa atggatgtta aggcatccag acgtctaaat
    33721 caatcaggtt tatgcgaaga gcactttctt gcaggtcgaa acatgcgata ctagcgtcac
    33781 atgccttatt aaggagctat aaaaggtggc gaagagcgta cccgcaattt ttcttgaccg
    33841 tgatggcacc attaatgtcg atcacggtta tgtccatgag atcgacaact ttgaatttat
    33901 cgacggtgtt attgacgcca tgcgcgagct aaaaaaaatg ggctttgcgc tggtggtagt
    33961 aaccaaccag tctggcattg ctcgcggtaa atttactgaa gcacagtttg aaacgctgac
    34021 cgagtggatg gactggtcgc tggcggaccg cgatgtcgat ctggatggta tctattattg
    34081 cccgcatcat ccgcagggta gtgttgaaga gtttcgccag gtctgcgact gccgcaaacc
    34141 acatccgggg atgtttttgt cagcacgcga ttatttgcat attgatatgg ccgcttctta
    34201 tatggtgggc gataaattag aagatatgca ggcagcggct gcggcgagcg tgggaacaaa
    34261 agtgctggtg cgtacgggta aacctattac gcctgaagca gaaaacgcgg cggattgggt
    34321 gttaaatagc ctggcagacc tgccgcaagc gataaaaaag cagcaaaaac cggcgtaatg
    34381 attaaaagat gagcggttga aataaaaatg catttttccg cttgtcttcc tgagac
//
LOCUS       DAPOXO010000053        34048 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPOXO010000053 DAPOXO010000000
VERSION     DAPOXO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34048
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.053"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            162..1022
                     /locus_tag="ROH59_002975"
                     /pseudo
     CDS             162..1022
                     /locus_tag="ROH59_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525915.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1088..1378)
                     /gene="ilvN"
                     /locus_tag="ROH59_002976"
     CDS             complement(1088..1378)
                     /gene="ilvN"
                     /locus_tag="ROH59_002976"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDX4805430.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            complement(1382..3070)
                     /gene="ilvB"
                     /locus_tag="ROH59_002977"
     CDS             complement(1382..3070)
                     /gene="ilvB"
                     /locus_tag="ROH59_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HDX4805431.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVSASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFSIAQS
                     GRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEESIRDAAAMINAAKHPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPLVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYKQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNEADPQAALQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            complement(3176..3274)
                     /gene="ivbL"
                     /locus_tag="ROH59_002978"
     CDS             complement(3176..3274)
                     /gene="ivbL"
                     /locus_tag="ROH59_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HDX4805432.1"
                     /translation="MTTSMFNAKLLPTAPSAAVVVVRVVVVVGNAP"
     gene            3675..4859
                     /gene="emrD"
                     /locus_tag="ROH59_002979"
     CDS             3675..4859
                     /gene="emrD"
                     /locus_tag="ROH59_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HDX4805433.1"
                     /translation="MKRHRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVSTSSLMVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLIPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQ
                     PV"
     gene            complement(4867..5364)
                     /locus_tag="ROH59_002980"
     CDS             complement(4867..5364)
                     /locus_tag="ROH59_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDX4805434.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQLGIRSVQLI
                     PHLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDTTLQKWCGSEKS
                     QPRRDCQACDWHRLCPHAREDKPDNVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(5361..5723)
                     /locus_tag="ROH59_002981"
     CDS             complement(5361..5723)
                     /locus_tag="ROH59_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HDX4805435.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            complement(5713..6060)
                     /locus_tag="ROH59_002982"
     CDS             complement(5713..6060)
                     /locus_tag="ROH59_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HDX4805436.1"
                     /translation="MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLFIISLILMV
                     VAVIVMGLVLYAG"
     gene            complement(6120..7614)
                     /locus_tag="ROH59_002983"
                     /pseudo
     CDS             complement(6120..7614)
                     /locus_tag="ROH59_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
     gene            complement(7611..9326)
                     /locus_tag="ROH59_002984"
     CDS             complement(7611..9326)
                     /locus_tag="ROH59_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HDX4805437.1"
                     /translation="MNSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKA
                     PVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGI
                     ATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQLSDG
                     AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFM
                     QGIEQLTTVHAEKLNSVGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLA
                     EGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPLVGFFG
                     AVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVMV
                     APWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITI
                     NYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKTAS
                     IGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPD
                     AKDSL"
     gene            9493..10359
                     /locus_tag="ROH59_002985"
     CDS             9493..10359
                     /locus_tag="ROH59_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418136.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDX4805438.1"
                     /translation="MNGKLQSSDVKNETPYNIPLLINENVISSGISLISLWHTYADEH
                     YRVIWPRDKKKPLIANSWVAVYTVQGCGKILLKNDEQITLHGNCIIFLKPMDIHSYHC
                     EGLVWEQYWMEFTPTSMMDIPVGQQSVIYNGEVYNQELTEVAELITSPEAIKNNLAVA
                     FLTKIIYQWICLMHAVGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLR
                     RLFLRYTGKTPKEYYLDARLDLALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKHKFG
                     YAPSAVLKNTDR"
     gene            complement(10449..12110)
                     /locus_tag="ROH59_002986"
     CDS             complement(10449..12110)
                     /locus_tag="ROH59_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HDX4805439.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGVGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMAMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESTRTNGGALIRTINIRVENPNLHN
                     LAIKDVPILNGDKVICSRLKREETLKVPSPETVIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASSD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFIHTLVDGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(12308..12736)
                     /gene="ibpB"
                     /locus_tag="ROH59_002987"
     CDS             complement(12308..12736)
                     /gene="ibpB"
                     /locus_tag="ROH59_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HDX4805440.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            complement(12848..13261)
                     /gene="ibpA"
                     /locus_tag="ROH59_002988"
     CDS             complement(12848..13261)
                     /gene="ibpA"
                     /locus_tag="ROH59_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HDX4805441.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     misc_feature    complement(13255..13327)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            13567..13899
                     /locus_tag="ROH59_002989"
     CDS             13567..13899
                     /locus_tag="ROH59_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDX4805442.1"
                     /translation="MIKNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVLDTILLPWDVFRKDSSVRSRVEKSEADAQETNNVI
                     PPAKMPAN"
     gene            complement(13903..15117)
                     /locus_tag="ROH59_002990"
     CDS             complement(13903..15117)
                     /locus_tag="ROH59_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312656.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HDX4805443.1"
                     /translation="MKQITFAPRNHLLTNTNTWTPDSQWLVFDVRPSGASFTGETIER
                     VNIHTGEVEVIYRASQGAYVGVVTVHPKSEKYVFIHGPENPDETWYYDFHHRRGVIVE
                     SGKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERVSFTYNDHVMHELDPALDLRNV
                     GVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAF
                     IGDTLSPKGEKVPELFIVELPQDEAGWKVAGDAPLSGTETTLPAPPRGVVQRRLTFTH
                     HRASPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQ
                     SAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTENHANPPSADAVVFSPDGQWLAWM
                     EDGQLWITETDR"
     gene            15218..16318
                     /gene="cbrA"
                     /locus_tag="ROH59_002991"
     CDS             15218..16318
                     /gene="cbrA"
                     /locus_tag="ROH59_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance protein"
                     /protein_id="HDX4805444.1"
                     /translation="MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSK
                     PCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA
                     FDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM
                     VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAY
                     PMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG
                     FISASSLEGISYALDSAEILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA
                     PALRKWIMRSGVAHIPQLKDYPTRFTSPTSRM"
     gene            complement(16279..17616)
                     /locus_tag="ROH59_002992"
     CDS             complement(16279..17616)
                     /locus_tag="ROH59_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4805445.1"
                     /translation="MVSGFAMPKIRRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICY
                     VDRANLAVASAHIQEEFGITKAQMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIA
                     IFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
                     TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKA
                     ELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLT
                     WFPNYLTQEKGITALKAGFMTTVPFLAAFIGVLLSGWVADLLVRKGFSLGFARKTPII
                     CGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVF
                     NFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG"
     gene            complement(17691..18839)
                     /gene="dgoD"
                     /locus_tag="ROH59_002993"
     CDS             complement(17691..18839)
                     /gene="dgoD"
                     /locus_tag="ROH59_002993"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HDX4805446.1"
                     /translation="MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELSDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            complement(18836..19453)
                     /gene="dgoA"
                     /locus_tag="ROH59_002994"
     CDS             complement(18836..19453)
                     /gene="dgoA"
                     /locus_tag="ROH59_002994"
                     /EC_number="4.1.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HDX4805447.1"
                     /translation="MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTALDAGAQALKIFPSSAFGPQYIKALKAVLPPNIAVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            complement(19437..20315)
                     /gene="dgoK"
                     /locus_tag="ROH59_002995"
     CDS             complement(19437..20315)
                     /gene="dgoK"
                     /locus_tag="ROH59_002995"
                     /EC_number="2.7.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HDX4805448.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQGDHCLDSRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREENTPVVMAGMVGSNVGWKVAPYLSIPARFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARTLAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENAVDAFAAGLERGLNAPAVLPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVAHQQVITLVAGTSLTARYQQAFQAMGCDVTAVAGD
                     TAFQAGIRNIAHAVAN"
     gene            complement(20312..21001)
                     /gene="dgoR"
                     /locus_tag="ROH59_002996"
     CDS             complement(20312..21001)
                     /gene="dgoR"
                     /locus_tag="ROH59_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HDX4805449.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            21280..21936
                     /locus_tag="ROH59_002997"
     CDS             21280..21936
                     /locus_tag="ROH59_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805450.1"
                     /translation="MKLNFKGFFKAAGLCSLAFALTGCITWGLVSNTASRPHAEQWRS
                     DTIKGLSLAEDSNGTKGYVFVGESLDYLLTTGGDEVVNMLNDPAIHGERITVSDNAKF
                     ILSSSNKNFSGAITLYYDWNNEEDKALATQYGFICDTRRCTWMLDGLKGSIHQKNKKA
                     DYSNVMVFHQPFTVGFYEYKATDGVPRGLVNALLPVTLTLDIVTSPLQFLILCTTRNC
                     "
     gene            complement(21980..22792)
                     /gene="yidA"
                     /locus_tag="ROH59_002998"
     CDS             complement(21980..22792)
                     /gene="yidA"
                     /locus_tag="ROH59_002998"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDX4805451.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(22906..23304)
                     /locus_tag="ROH59_002999"
     CDS             complement(22906..23304)
                     /locus_tag="ROH59_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418153.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HDX4805452.1"
                     /translation="MGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGL
                     GAILSTWLSNQQSNQSVSGEQVESALGTNAVSDLGQKLGVDTSTASSLLAEQLPKIID
                     ALSPQGEVSPQANNDLLSAGMELLKGKLFR"
     gene            complement(23448..25862)
                     /gene="gyrB"
                     /locus_tag="ROH59_003000"
     CDS             complement(23448..25862)
                     /gene="gyrB"
                     /locus_tag="ROH59_003000"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDX4805453.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTETDLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(25891..26964)
                     /gene="recF"
                     /locus_tag="ROH59_003001"
     CDS             complement(25891..26964)
                     /gene="recF"
                     /locus_tag="ROH59_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDX4805454.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(26964..28064)
                     /gene="dnaN"
                     /locus_tag="ROH59_003002"
     CDS             complement(26964..28064)
                     /gene="dnaN"
                     /locus_tag="ROH59_003002"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDX4805455.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(28069..29472)
                     /gene="dnaA"
                     /locus_tag="ROH59_003003"
     CDS             complement(28069..29472)
                     /gene="dnaA"
                     /locus_tag="ROH59_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDX4805456.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            29769..29849
                     /locus_tag="ROH59_003004"
     CDS             29769..29849
                     /locus_tag="ROH59_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805457.1"
                     /translation="MTIDKKWLNRSNKDPGRSLRFTRQPV"
     gene            30079..30219
                     /gene="rpmH"
                     /locus_tag="ROH59_003005"
     CDS             30079..30219
                     /gene="rpmH"
                     /locus_tag="ROH59_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDX4805458.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            30236..30595
                     /gene="rnpA"
                     /locus_tag="ROH59_003006"
     CDS             30236..30595
                     /gene="rnpA"
                     /locus_tag="ROH59_003006"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDX4805459.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            30559..30816
                     /gene="yidD"
                     /locus_tag="ROH59_003007"
     CDS             30559..30816
                     /gene="yidD"
                     /locus_tag="ROH59_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDX4805460.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            30819..32465
                     /gene="yidC"
                     /locus_tag="ROH59_003008"
     CDS             30819..32465
                     /gene="yidC"
                     /locus_tag="ROH59_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDX4805461.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            32571..33935
                     /gene="mnmE"
                     /locus_tag="ROH59_003009"
     CDS             32571..33935
                     /gene="mnmE"
                     /locus_tag="ROH59_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDX4805462.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGLKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
BASE COUNT         8263 a         9080 c         8587 g         8118 t
ORIGIN      
        1 cttgcactaa tcctgaaagg tcgaatattt cgcagacaca gcacatgcaa cttgaagtat
       61 gacaagcatg cctgcttcat tattacattt taataataaa acccaccgat taatgtacaa
      121 aaaaatccct gcgtgatatt gtctgtaaaa aaggagcaga tatgcacact caccctcact
      181 taataaaaca aactcttgtt ccacgactca ttaatgaaat aaacaaaaga acacaaagca
      241 atagtgagaa gttatcaaac agtgataaat taacatatat taatgacaac tactgtgaga
      301 taacacgaaa ctacacgtca ttttatggca tgaacattct gagcatcgtt ctttttttac
      361 ctatcgttat tttatgtttt ggctctgttt tattctttat atatgacatt atatttaact
      421 tcgaacgata cttagatacg tggagatacc gcgcagactc tgagttactg ctacatattg
      481 cttactgcgc aatttttttc atgtcttttg tttttgctgc tatcctaaat tattttatct
      541 ttgccccgcg acattaccca attcgtttta atagaaaaac aggaaaggtc tatatttgta
      601 attatattct taatgatatg agtcataaat cgacctatac cttctggtag cactacccat
      661 tctacaaaca tactaagcct gaatataaag agtacgactg ggaacaaatt caaggtatag
      721 ctttttttgc gcaaaatcac cattccacat acgccaccat tcgctgtatt gtttatgaat
      781 cattagacag tacaaatatt attgacacct ttaacctgat aacgacagag agtgctacaa
      841 atgcattgca tatgacaaat aacaaattat ggttatggat taatagcttt atgaattttg
      901 acgatgagtt tttagagaaa tctatcaaca ctgctccagg tatttggggc cgtgaagtga
      961 attggcctga tgatatgaat aagaaatcaa tgttgtcttc aatggacgaa tatatactct
     1021 gaataatttg agttgcagaa tataagctcg cccggatgta aatatcccat ccaggcgaga
     1081 aaatcactta ctgaaaaaac accgcaatct tgttaaacat cgtcgggtcg gactgattac
     1141 gctgcacttt caccacatct tccagcttgt cgatttggct tatcatctgc tccagacgct
     1201 ggtcgtcatt gaccagtagc cagatgtggc ttttgtcgct gtcctgaatc ggcaggcaga
     1261 gaatgccttc aacgttaaaa gcgcggcggg caaaaaggcc acaaacgtgg gtcattacac
     1321 ccggatgatt gcgaacggtg agctccagaa tcacgttatc atgagttgtg ttttgcatgg
     1381 cttattcccc caccatttca gtattcgccg cacctggcgg caccatcggg tacacttttt
     1441 cttcggcatc aatgcgcaca tggatcagcg ccgggccagg gcgattgatg atttcctgca
     1501 atgcagcctg cggatcggct tcgttattca aatcacaggt ttcgaggccg aatccggcgg
     1561 caatctgcat aaagttgatt ttgcccggat aggtagcggc aaaaacgccc tgcttgtaga
     1621 acagactctg ttgctgatgc accagcccca gcgcttcgtt gttcatcaaa atgattttaa
     1681 catccagctg attttcactg gcggtcgcca tctcctgaat attcatcatc aggctgccgt
     1741 cgccggagaa gcacaacact ttgcggtccg ggttcgccag cgccgcgcca atcgccgcag
     1801 gcaggccaaa acccatcgtg cccagcccgc cggaggtcag ccactggcgt gggcgattga
     1861 gcggataggc ttgcgcggtc cacatctgat gctgacccac gtcggtagtg ataatcgcat
     1921 tgtcatcgac acaggcggca acggcgttga tcaggccgta atggcttaat ggatcgcacg
     1981 ctttcgggat tggacacggg aattcacgct gcaaatccgc caccaactgg tgccactctg
     2041 cacgcggttg cgcttccacc agcgggatca actgcgccag cacgtcatca acatccgcct
     2101 gaattgccac atgcggttgc ttgattttgc ccagctctgc gcggtcgata tcgacatgaa
     2161 taattttggc attcggacag aactgctctg ttttgccaat cgcccggtca tcaaaacgcg
     2221 caccgagtac aatcagcaga tccgcctcct gcaaaatata gttggtgctg cgcacaccgt
     2281 gcatccccag catacccagc gacagcggat gcgcttttgg caacataccc agcgccatta
     2341 aagtcatggt ggtaggcagt tgcgctttct ccgccagttc acgcactcgc gcaggcgcgt
     2401 tgatcacacc accacccaga taaagcaccg ggtgtttggc ggcgttaatc atcgccgccg
     2461 cgtcacgaat actttcttcg ctaaaggcgg gtgcggcggc tttttctgcc atagcgggct
     2521 gtgtttcaat ctcaaaaact gccgtttgca catccttagg aatgtctatc cacaccgggc
     2581 cagggcggcc tgattgcgca atgctgaagg catcgctcat gacctgcggg agttcttcga
     2641 tatgtctgac cagatagttg tgtttggtga tggggataga gatgccgtag gtgtcgactt
     2701 cctggaaggc gtcggtgccg atcatcgagg cggaaacctg accagtgatg caaatcagcg
     2761 ggatggagtc cagcctcgca tcggcaatgg cggtcaccag gttagtcgca cccggtccgc
     2821 tacaggccat acagaccgcc ggtttaccgt cggtgcgcgc cattccctgg gcgataaacc
     2881 ccgccccttg ttcgtggcga gccagaatat ggcggatttg cgtgctttgg cttaaggcat
     2941 cgtaaacagg caggatagaa ccgcccggaa tacccgtcac aatcttaatg ccctgctgtt
     3001 ccaggaaatg aacgataaat tctgcgccgg taaagcgctt acgcgtcgat gttgtgcccg
     3061 aacttgccat gctccagtcc ttttcttctg ggccgacttt ccgggaggtg cttaaacgaa
     3121 aaaccccgcc cggtttgcgc cggcggggtt ttggaatcgt gtgttgttcc agtccctacg
     3181 gcgcattgcc gacgaccacc accacacgca cgacgaccac tgcggcggat ggcgcagttg
     3241 gtagtagttt tgcgttgaac atggaagtag tcattaggga ccttgttggt tttgtgttta
     3301 acaatattta tacaagcaca gctttacagg ggagacaatg gaaaattttt cttccggata
     3361 aaaatacgtg gcagatcaca ttttgaactg aaactcaggc aataaagcat catcacctga
     3421 aagacggtca ggttgttgac agagtgcgcc ttattcatgt cgaatacagc gtaaacactt
     3481 tactctacca accgcaccac cactgtttcc ggcaacattt attgccgctt ttgtttacat
     3541 attctgccgc taaacaattc cccattcctg gcgtatatct ggctaacatt catcaatgtg
     3601 atagattcct ctcccgcatt tatgggaatg cgtagtgact tattctaatt atttttataa
     3661 aagcatccgt gataatgaaa aggcatagaa acgtcaattt gttattgatg ttggtattac
     3721 tcgtggccgt cggtcagatg gcgcaaacca tttatattcc agctattgcc gatatggcgc
     3781 gcgatctcaa tgtccgtgaa ggggcggtgc agagcgtaat gggcgcttat ctgctgactt
     3841 acggtgtctc acagctgttt tatggcccga tttccgaccg cgtgggtcgc cgaccggtga
     3901 tcctcgtcgg aatgtccatt tttatgctgg caacgctggt cgcggtctcg acctccagtt
     3961 tgatggtatt gattgccgcc agcgcgatgc aggggatggg caccggcgtt ggcggcgtaa
     4021 tggcgcgtac tttgccgcgc gatttatatg aacggacaca gttgcgccac gctaacagcc
     4081 tgttaaacat ggggattctt gtcagtccgc tgctcgcacc gctaatcggt ggtctgctgg
     4141 atacgatgtg gaactggcgc gcctgttatc tctttttgtt ggttctttgt gccggtgtga
     4201 ctttcagtat ggcccgctgg atgccggaaa cgcgtccggt cgacgcaccg cgcacgcgcc
     4261 tgcttaccag ttataaaacg cttttcggta acagcggttt taactgctat ttgctgatgc
     4321 tgattggcgg tctggccgga attgccgcct ttgaagcctg ctccggcgtg ctgatgggcg
     4381 cggtgttagg gctgagcagt atgacggtca gtattttgtt tattctgccg attccggcgg
     4441 cattttttgg cgcatggttt gccggacgtc ccaataaacg cttctcaacg ttgatgtggc
     4501 agtcggttat ctgttgcctg ctggctggct tgctgatgtg gatccccgac tggtttggcg
     4561 tgatgaatgt ctggacgctg ctcattcccg ccgcgctgtt ctttttcggt gccgggatgc
     4621 tgtttccact ggctaccagc ggcgcgatgg agccgttccc cttcctggcg ggcaccgctg
     4681 gcgcgctggt cggcggtctg caaaacattg gttccggcgt gctggcgtcg ctctctgcga
     4741 tgttgccgca aaccggtcag ggcagcctgg gattgttgat gaccttaatg ggattgttga
     4801 tcgtgctgtg ctggctaccg ctggcgacgc ggatgtcgca tcaggggcag cctgtttaag
     4861 ctcacgtcac cgcagcatcg tcatcagctc catgggagaa cgatgctgct ttatcagatc
     4921 acgcatcacc cgcatatgcg gcgcggagta agaataaaac gcctgatagc ccgcacaaag
     4981 cacgttgtct ggtttatctt cccgagcgtg cgggcacagg cgatgccagt cgcacgcctg
     5041 gcagtcacgg cgcggttgcg acttttcgct gccacaccat ttttgtaagg tggtgtcaaa
     5101 aagttcaatc gaaatacgac tgatatctgc ccgcacccaa cactcgaaca gggcaattaa
     5161 aaatttcccc cacagctctg ctgtcaccga agcggccgtc agatcgcccc ggtcatcaaa
     5221 ttcaagatgg ggaataagct gtactgagcg gatgcccagc tgtttgaaat tgtgataaaa
     5281 atcggcaggt tgcagagcat ccttatactc tacaaccagt ttatgcctgt cctcttcagc
     5341 atcaatgacc tgacttcctg tcatgcgact ctctcaataa atacgataag ttgatgtata
     5401 tgcgttacag caaacagtat tgcgagagat aacaccgcga gggagatcaa aaatttgtca
     5461 cggactacgt gaaattggga aaaatcgcta ttcgtgacat ccattaaatt gcgattacgg
     5521 gtgtagtgcc agaggatcag cgccacaatg gcgaggatgc caatcgaaat ccagaataac
     5581 atgcccgcct ggtgccagtt gtgtttgata gccaacgcca tcaacgcgcc gtagcccagc
     5641 atggtacgaa accacgccag tgatgtgcgt tccggctgca gccctgggtc ggcaatgcgt
     5701 ctggctttgc ggctatccgg catacaacac cagtcccatg acgatcactg ccacgaccat
     5761 caatattaag ctgatgatga ataagctgtt ggtatagggc aggtcctctt tcaggcgcat
     5821 cgctttttca ttgcgtaacc agcgcaagta gccatacatc gctaacccgc cggaaaacag
     5881 acacaacaac aacgccagca gttcgcggat gacgggcgtg gcgaaatctg gcgcaagttg
     5941 atcaagccca acccccgccg ccagaaatcc tagtgcagta cggatccacg ccagaaaagt
     6001 acgctcatta gccagcgaga agcggtaatc gggcgcttct ccgaggcggg aaattttcat
     6061 tgttgctcct tgtaaactgt tcctcgccga aaaattaggc caggaacagc aataatgcat
     6121 cagaacttct gttttttctc ttccaccttc accccttgtg tcggtaaacc ggtgtcatag
     6181 tcgcgtacca ctggagaata accatcctgt gggcgtggac gaaacgcccc catccagcgc
     6241 ggttgtgcat ctttgcgcca cggacgcagg ttccattgat aactgcggaa cggatcgcga
     6301 attttgtcca tgtaatccaa taaggcgtca tgcattttgc tgcgaacgtc ggcaaaatgg
     6361 atatcatcga tcaggttatg catttcattt gggtcattac ggcgatcgta aagttcatca
     6421 ctggtgaaga ggttgagcac cagtttaaag tcatccgtta cccagcaacg caccggaata
     6481 aaaccgccaa agctgtcatg ctcaatctcg tagcgattaa attccaccaa cacgccacgt
     6541 ggttctttta cggcaaggat attttccccc ggcagaatct ctggtttttc aatatctgcc
     6601 agcgccatca ttgtcggcag taagtcaata tgactgactg gcgtatcgac ctgtcgccgc
     6661 tccccttgcg gcgaacggat gatcagcgga atgcgggtga tgtcgtcata catcgccgct
     6721 cctttactga tcagcttatg tgcgcccatc atttcgccgt gatcggaggt ataaataacc
     6781 cacgtatttt cacgttgctc tggcgttaag gcgttgatga cccgtccgat ttggtcatca
     6841 acaaagtcat tgcaggcaaa atagagcgga tggtgataaa gcccgtcatc accgactggc
     6901 gatggcatcg cctgcgccca taagcggtga tgttccggtt tgttcgccag gtcatcctct
     6961 gctttctcac ccagttcgta gtaaaaatca gtgtatttct ctaaatactc caccggacag
     7021 gtgaacgggt gatgcggctc atcatacgaa atcaccatca ggaaaggttc gtcggcgcgc
     7081 gcgggctgtt gcagaaaatc caccgcccga ttgctgatgc ggtgcgccca ggtgaaggtt
     7141 tcgtcaatat ggttcgcctg taaatcttcg acgctgttta ggccattgcg ccacaggcta
     7201 atctcttttt ccgtcagttc actaagatag ttcgccccat cgaaccagta atcagcgtcc
     7261 cactccggcg gacactcgcc aggtgccgaa atagtcatga ccgtcgagat gccatttgcc
     7321 gatgtaacag gtgtgatagc cggcatcctt aaagtagcgc cccatagtgg agatgttttt
     7381 gcctggcgcg acgttgttgg tccacgggcc ggactggtta gcgtagatac cggtgaatag
     7441 tccggcgcgt gcaggcgtac aaaccggtga acaggtgtag gcggagttaa agcgaatacc
     7501 ttccgccgcc agactatcaa tattttgcgt attcagcggc ttaccgctat agcaaccgac
     7561 catattggtg gcctgggtat cggtcatgat gaacagaaaa ttggggcgtt tcataggcta
     7621 tcctttgcat cgggagtaaa ggttacggct gggtcgtgac gatgccgcca gctgtcaaaa
     7681 atcaggtaga caatcactac ggcggcaatg aaataactga tcatcgctaa ccagcgcgta
     7741 ccgtagccgc cgaattcagc cagcccggca tagacgccaa tcatcgcgaa caggatacca
     7801 attgacgcag tcttgacgtt tttccacggt ttcatgtcca ccgcaaacgc atctttgaag
     7861 gtgaacggcg tggcgcgcgg tttgataaaa ccgatcacca gcatcacgac cacgttgatg
     7921 cagaacgtac aggccagcac atagaggaaa tggaagtcga acttcaccag atagttgatg
     7981 gtgatgtagc tgattatgcc aatccccatc gccacttttg ccgccagcgc cggaatgcgc
     8041 gggaagaaaa agcccataat gatgatggta accagcggca cgttgtaaat accgttgagc
     8101 tgtttcatcc agctatacag cccctgcggc gcgttggcga tccacggcgc gaccatcacc
     8161 gaaacgatgg cgataaagaa accaaatttg cgcccgacgg tgaccagctg ttgcggctcg
     8221 gcattctggt taatgatacg ccggtaaata cccatactga ataacgtact ggcgctattc
     8281 agaaagccgt tgaaggtact gatcaccgca ccaaataaca ccgcaccgaa gaagcccacc
     8341 agtggcaccg gcagaacgtt attgaccagc gtcgggtagg ccatgtcggc tttcggtaaa
     8401 tcctgataca gatgaaacgc aatcaacccc ggcagcacca gtaccagcgg gtcgagcatt
     8461 ttcagcaccg ccgttaacag tgcccccttt tgcccttccg ccaggctttt tgacgccagc
     8521 gtgcgttgca cgatgccctg attggtacac cagtaaaagg tgttaaccag aatcaaaccg
     8581 gtaaatgccg cgccaatcgg caagggatcg gtcgggccac cgactgagtt taatttctcg
     8641 gcgtgaacgg tggtaagttg ctcaatgccc tgcataaagc tgcccttgcc catcgcgatc
     8701 aggccaaata ccggcaccat caacccgcca ataaccagcc caataccatt gatggagtcc
     8761 gccactgcca ttgcgcgcag tccgccgatc accgcataca aaattcccgc cagaccaagc
     8821 aaaataacca gtaaccagat agccgcacca tcggaaagtt gtagcgactc acccacatga
     8881 aacaggctgt tgagcgccaa cgcgccggaa tagagaacaa tcggcagaaa gcagacgccg
     8941 gtggcaatga ggaagcagaa gtcgatgata atacgcgtcg ttttatcata acgttcctcc
     9001 agaaaatcgg ggatggtggc aatgccgcgc ttcagatagc gcggtaaaaa gattagcgcg
     9061 aggaagatca gcgtcactgc agaggtgact tcccagccca tcaccgacat gccgcttttg
     9121 taggcctgcc cggaaaggcc gaccagttgt tccgtggaaa ggttggttag cattaacgaa
     9181 gcggcaataa ccggcgcttt tagtgaacgt ccggcaagaa aatagccttg ttgcgatccg
     9241 gtatctgttt tacggacctt ccaccaggtg atgaccgcca ccagcagcgt aaaaccgaca
     9301 aaactcaaga tttgtaacga attcatctca tagcccttat ttatgtttat gtcccggacg
     9361 catgaatata gggagaggta aaatgcgtcg ggtcaggcag tcagattctt aaaatacaaa
     9421 cgtcgtatcc ctgaacggat tgttttctgt taagttcagg ttgtgagcat aattcgccgg
     9481 agggatatta aaatgaatgg aaaattgcaa agttcggatg taaaaaacga aactccgtac
     9541 aatattccct tattgattaa cgaaaatgtg atctccagcg gaatttctct gatatcgctc
     9601 tggcatacct acgccgacga gcattatcgg gtgatctggc cgcgggacaa gaagaaaccg
     9661 cttatcgcca actcatgggt tgcggtgtat accgtacaag gatgtgggaa aattctttta
     9721 aagaatgacg aacaaataac tctgcatggc aactgtatta tatttttaaa gccaatggat
     9781 attcactctt atcactgtga aggtttggtc tgggaacagt actggatgga atttaccccc
     9841 accagtatga tggatattcc cgtcggtcag caaagcgtta tttataatgg cgaagtttat
     9901 aatcaggaac ttaccgaagt tgctgagtta attacttcac cagaagcaat aaaaaataat
     9961 ctggcagtcg cttttctgac gaaaattatt tatcagtgga tttgtcttat gcacgcagtc
    10021 ggtaaaaaag atccacaacg gcggcaaatt gaaaaattaa ttgccacttt acatgccagt
    10081 ctacaacaac gctggagcgt agctgatatg gctgccacga tcccctgtag cgaggcctgg
    10141 ttgcgtcgtc tgtttttacg ctataccggc aagacgccga aagaatatta cctcgatgcg
    10201 cgtctggatc tggcgctatc gctattaaag caacaaggga actcggttgg cgaagtcgct
    10261 gatacgctca acttcttcga ctcctttcat ttcagcaaag cctttaagca taaatttggt
    10321 tatgcgccgt cagctgtgct gaagaatacg gacaggtaat aaccagaatg gcgagtgtgt
    10381 aaatgactcg atgatgttca gaaataccag gcggagtacc atttacggcg actccaccgg
    10441 gaaaagagtt aaccgatact ccagaagagc accgccagta attggggtgt gataatgcgc
    10501 aggaacatca ctaacggata gacagtggcg taagagagcg ccgctgcacc gctggttgga
    10561 tgaagattat tagcaaacgc cagcgccgga ggatcggtca tggaacctgc cagcatcccg
    10621 cacatggtca ggtaattcat tttggctaac atccgcgcca gaataccaac agtaatcagc
    10681 ggaacggcgg tgatcagggc accataacca atccagctta gcccttcgcc atccaccagt
    10741 gtatggataa aatcgccgcc ggatttcagg ccaacgaccg agaggaacag tacgatcccc
    10801 agctcccgca gcgcgaggtt ggcgcttggc ggcataaacc agtacagctt gccgatactg
    10861 ccgatacgcc cgagaatcaa cgccataatc agcggaccgc ccgccagccc cagtttcaac
    10921 gcggccggaa atcccggcac aaagacggga atagaaccta acaatacgcc aagcccgata
    10981 ccaataaaca ctggcagcat ctgaacctgt tgcagttttt gctgcgcatt ccccagcaca
    11041 ttggcaacgg catcaattgc ggacggacgc cccaccaggt tgaggatatc gccgaactgc
    11101 aggctgatat cgctacttgc aactaattca acaccagcac ggttcaggcg cgagataaca
    11161 acgtcatagc gttctttaaa gtgcaggtcg cgaatacgtt taccgagcac gttttcattg
    11221 gtgaccacca cacgctcgac gcgcaaatca gtgcctttcg tagacagcga ggtatcgacc
    11281 tcctgaccaa tcaccagttg cgcattatgt aaatccgcag gctgccccac cagatgcagc
    11341 aaatcgccca gttgaataac ggtttctggc gaaggcactt ttagggtttc ttctcgtttc
    11401 aatcgtgagc aaataacttt atcgccattg agaatcggca catctttaat ggctaaatta
    11461 tgcaaattag gattctcaac tcggatgtta atcgtcctga ttagcgcacc gccgttggtt
    11521 cgcgtggact cgtgctgctg ggcctcagtc tcaacattga cgcggaaaat aacccgcagc
    11581 atccacatag tgaacaaaat gccgcaaatc ccaaatggat acgccatcgc atagctcatc
    11641 cccatttgat cgaccatcgc catcggtgtc cccaggtcgc gcaagatctg ctgccctgcc
    11701 cccagcgctg gcgtattggt gaccgcgccg gaaaaaatcc ccagcacgac cggcagtgga
    11761 atatcaaaca gtttatgcag gatggcggta accagaccac cgatgatgac gatcagaaca
    11821 gcaaacaggt tgaggcgtaa tccggagacg cgcaatgagg caaagaagcc cggccctacc
    11881 tgaatcccga tggtataaac gaacaggatc aggccaaatt cctgaataac atgcagcata
    11941 tcgctactta atgtcatccc cgcctgagaa acaaaatggc cgacgatgat cccgccgaac
    12001 agcacgccgc caatgcccaa tccaacaccg cgaaacttga cgttgccgat aaacaacccg
    12061 acgaccgcca ccaaagccag aatactgacc gttaatgcta tatcactcat cgtccatttc
    12121 tcttgaaata acattttaat tgctacggat tatggctgaa tcggtgaagc agatttgcct
    12181 tatagcgcac attatcacgg gaaagaacgt gccgaaatat cttaaacagg cgaaatttaa
    12241 cgcattgttg aagaaaaaag acaaaaaaaa agccccacca gaatggcggg gcaaagagaa
    12301 tagctagtta gctatttaac gcgggacgtt cgctgatagc gatacgctgc gctgcgatgg
    12361 gttcaggctc attacgaatt aaatcaatat gcagtaaacc gtttacgaag gttgcgccag
    12421 agacttccat attttcagcc agcgtaaagc tcaggctaaa aggctgattc ataagccctt
    12481 gatgcagcca ttttttctct tcttttggct gctccggtgt gccttttacg ctcaggcgcg
    12541 taccttccag ttgaatctct aaatcttcct gacgaaaacc tgccagcgcg agggtaatgc
    12601 ggtagtggtt atcgtcgctt ttctcaatgt tgtacggcgg gaagctctgg ctttcaccgg
    12661 cgttttgcag tgcgttggcc agtttgtcaa aaccgatcca ttgacgcatc agtggggata
    12721 aatcgaagtt acgcatagtc atttctcctt ctaagaagcg agtaagtacc tgcaaatccg
    12781 aagattcgca tatgctccct gacggcgagc atggagatgt caggccgcgc caggcggcct
    12841 tagggaatta gttgatttcg atacggcgcg gttttttcgc ttccggaatc acgcgttcga
    12901 gatcgatata cagcagacca ttcaccaggt tagcaccacg aacatgaatg ttctcagcta
    12961 actggaattt acgttcaaag ttgcgttcag cgatgccctg gtacagatag gtgcgctctt
    13021 tttgttcgtc ggcgtgagca cctttcacca ccagcagatt atcctgggcg gtaatttcca
    13081 gttcgctctc agcaaaacca gccacagcga tagcaatgcg gtaatggttt tcgtctacca
    13141 gttcaacgtt atacggaggg tagccgccat tactctggct ctggttgttt tctaagtggt
    13201 taaacaaacg gtcaaatcca atagcagaac ggtaaagcgg ggataaatca aagttacgca
    13261 taatcaatag ctcctgaaat cagcgagaat ctaagacctt ccacaatgga caggtcaggt
    13321 agccagaaca cccatcaggc gcgtcctcat cggctacgat gtaaaaatgg gtctggaaat
    13381 gaacttttca agccttatca gcggactttt ttttgcagtt tatggtctat tgcatagact
    13441 gagggggcag cacgaaacgt taaagtgcga tagccgccac agtgcgacgt aatgatgatg
    13501 ttattttcag caagggatcg ctataactca tcaggccaac acccacgatc aacagatgaa
    13561 tttattatga taaaaaatgt gttgttagcg ttcatgatat gcagcggaat gacattactc
    13621 ggaggatgct ccagcgtgat gtcccatacc ggggggaaag aaggaacgta tcctggcacc
    13681 cgcgccagcg caaccatgat tggcgacgat gaaaccaact ggggcacaaa atcgctggcg
    13741 atactcgaca tgccatttac cgcagtactg gacacaatat tgctaccgtg ggatgtgttc
    13801 cgcaaagaca gctcagtgcg ctcgcgcgtt gaaaaaagcg aagccgacgc gcaagaaacc
    13861 aataacgtca ttccccccgc caaaatgcct gcaaactgag agctagcggt cagtttcggt
    13921 gatccacaac tgaccgtcct ccatccacgc caaccattga ccatccggcg agaaaaccac
    13981 ggcgtccgca gaaggtggat tggcgtggtt ttcggttaaa tactcaacct cgccgctttg
    14041 cgcatgggca caagcaatcc gattatccag cacaaatccc agccattcgc ctgatggatg
    14101 ccagttaaat gcagactgaa tatccgtttt attatgggtt aactggcgtg gttcaccgcc
    14161 ctgtggcgag ataagccaca gttgcacaat gccgttatca tcacgcatta aaaacgcgat
    14221 ttgcgtaccc tgcggattac agcgcaccca gtggcgcggg acgttgacta atcccggaga
    14281 agcccgatgg tgcgtaaagg ttaaacgtcg ctgcacgaca ccacgcggtg gcgcgggcag
    14341 ggttgtttcc gttccactta acggcgcatc acctgccact ttccagccag cttcatcttg
    14401 cggcaactcg acaataaaca gctccggcac tttctcgccc tttggcgaaa gtgtgtcgcc
    14461 aataaacgcc agcgcgtgat ttcctaccca tccttcttca taagcacgat tgatttcatc
    14521 actgccaggc tgtggcgtgg gcgtggtttt acttaccagc acgcaccagt ggctaccgct
    14581 gtattcacgc ggatgctgct tttgtacgtt gaccgggcca aacggtgcag caacaccgac
    14641 atttcgcaaa tccagcgccg gatcgagttc atgcattaca tggtcgttgt aggtaaagct
    14701 caccctttca ccgtttgggc taaagacatg tacatgactg ccgccgcgca gcgctcctgg
    14761 cgtatatggc gcggtaatat ccattgcatc gagattgctc accttgccgc tttcaacaat
    14821 cactccgcgc cgatgatgaa agtcgtaata ccatgtttca tcaggatttt ccgggccgtg
    14881 gatgaagaca tacttctctg acttcggatg aacggtcacc acgccgacgt atgcgccctg
    14941 tgacgcgcga tagataacct cgacctcgcc ggtatggata ttcacacgct caatggtctc
    15001 gccggtaaac gacgccccag aaggccgcac gtcaaacacc agccactggc tgtcgggcgt
    15061 ccaggtattg gtattggtga gcaggtgatt acggggagca aaggttatct gtttcatggc
    15121 gcggtcctga tacaaaacgg ttcccgccat catacttcac aaggacttca ctttcagaca
    15181 atagtctttt gccatcgtga tgaatgtgag tgaaaagatg gaacatttcg acgtggcgat
    15241 tattggcctc ggcccggcag ggtcggcgtt ggcgcgaaag ttagcaggca aaatgcaggt
    15301 gatcgcgctg gataaaaagc accagtgtgg tactgaaggt ttcagcaaac cttgtggcgg
    15361 tcttctggca ccggacgcgc agcgatcttt tattcgcgat ggactgacgc ttcctgtcga
    15421 tgtcatcgcc aacccgcaga ttttcagcgt caaaaccgtc gacgtcgccg catcgctcac
    15481 gcgtaactac cagcgaagct atatcaatat taatcgccat gctttcgact tgtggatgaa
    15541 atcgctgatc cccgccagcg ttgaggttta ccacgacagc ctgtgtcgaa aaatctggcg
    15601 tgaggatgat aaatggcatg tcatttttcg cgcagacggc tgggagcagc atattaccgc
    15661 ccgctatctg gtcggtgccg atggtgccaa ctcgatggtg cggcgacatc tctacccgga
    15721 tcatcagatt cgtaaatatg tcgccatcca gcagtggttc gcagagaaac atccggtacc
    15781 gttctactcc tgcatctttg ataatgcgat aactgactgt tactcatgga gtatcagcaa
    15841 agacggttat tttatctttg gcggtgccta tcccatgaaa gacggtcaga cgcgtttcac
    15901 gacgctaaaa gagaaaatga gcgcctttca gttccagttt ggtaaggcgg tgaaaagcga
    15961 aaaatgcacg gtgctgtttc cctcacgctg gcaggatttt gtctgcggca aggacaacgc
    16021 ctttctgatt ggcgaagcgg cgggatttat cagcgccagc tcgctggagg ggattagcta
    16081 tgcgctggat agcgcagaga ttctgcgttc ggtattactg aagcagccag agaagctcaa
    16141 taccgcttac tggcgcgcca ctcgcaaact gcgtttaaaa ctcttcggca agatagtaaa
    16201 aagccgatgc ctgaccgcac cggctttaag aaagtggatt atgcgcagtg gagtggcaca
    16261 tattccacag ttgaaagatt atccaacgcg cttcacatcg cccaccagca ggatgtaaga
    16321 gagcgcgcca atcaacgcga cggcggagat ataaaccagt gcaggcgcga aaccgtaacc
    16381 ctgcgccagg taccccacca ccagcggaac ggtgatgccg cccagaccac cggcaaagtt
    16441 aaacacgccg ccggttaaac caatcaggcg catcggtgcc agagaagaga ccagcgacca
    16501 ggttatcgaa gcaaaaccgt tgccgaagaa tgccagcgcc atcaggcaca taatcatcat
    16561 cggatcgttg gtgtagttcg cacccataat gcaggtggag atcagcaagc cgcagataat
    16621 cggcgtttta cgcgcaaagc ccagtgaaaa gcccttacgt accagcagat ccgcgaccca
    16681 gccagagagc aggacgccaa taaacgccgc gaggaatggc accgtggtca taaaacctgc
    16741 tttcagcgcc gtgattcctt tttcctgggt taaatagttc gggaaccagg ttaagaaaaa
    16801 ccacagtgta gaagccaccg caaattgccc aagatagaca ccgatcagtt tacgatggaa
    16861 caccagtttc cagtctttgg ctgttaacgg ctgacgcgcc tcttttttca ccggcgcatc
    16921 gccatccacc agaccgccgc catcacgaat gtaatccagt tcagctttgc tgatgccttt
    16981 ggtcagacgc ggcggctgat aaaccttaaa ccaaatcagc gaccagataa tgccgatacc
    17041 accggtgaca atgaacaccc agtgccagct caacatctcc tgaatccaga tcagcagcgg
    17101 agtcagaaac gccagaccga caaactgacc agacgtataa aaaccaacgg cagaagcgcg
    17161 ttcatgttcc gggaaccaac tggttaccat ccggttattg gtcgggaacg cgggcgcttc
    17221 gaaaataccg gttatcgcgc gcagaccaat taatgacatt aagcccgtgg caaagccctg
    17281 gaataacgtc gccactgacc agccaaatat cgcaataaaa taagtcacgc gtgaacctac
    17341 gcgatctaaa aaccaaccgc cggggatctg acatagcgta taaagccagg cgaaggccga
    17401 aaatacatag cccatttgcg ctttagtaat accaaactct tcctgaatat gggcagaagc
    17461 cacggccagg ttagcacggt caacataaca aatgaccacc gtaataaaga tcatcaccag
    17521 cgtcagataa cgccgacgcc ccggctttgc tgcattaacg ggaatatcca tagcgagctt
    17581 tctcctgatt ttgggcatag cgaagccgct caccatgcac tgtaatttac agagggttat
    17641 atttttgtat tgctgtttta gtgcccgatg aggggcttac gtggcaggaa ttaccactct
    17701 gctacgctgt tatcttcatg acgccagagc ggattacgcc agtccggggc atttttactg
    17761 aactcaataa ctttagcttc gtcgatttcc acgcctaagc ccggtttcgt taatggttta
    17821 aagaaaccgc cgaccatgct gaagtcctct ttgtttttca caaagtcgag taactccgcg
    17881 cctttgttgt aatgaatgcc catactttgt tcctgaagga cggcgttata ggaaacaaag
    17941 tcgatatgca ggcaagccgc cagtgcaatc ggtccgagcg gacagtgcgg cgcaagggtc
    18001 acgtcatagg cttctgccat tccggcaatt ttgtagcatt cggtaatacc gcctgcgtgg
    18061 gagagatccg gttgcagaat cgaaataccg cctgcctcca gcacacgttt aaaatcgaag
    18121 cgtgagaaca tgcgctcacc cgccgccagt ggaatatgcg tttgtgccgc cagtttcggg
    18181 tagtattcgg cctgttccgc cagcaccggc tcttcaataa acagcggacg atacggttcc
    18241 agctctttaa tcagcacttt cgccatcggc gcgctgacgc gaccatggaa gtccagacca
    18301 aactcaatct gattgccaaa agcttcacga atttgtgcca cggtgttgac tgccgcatct
    18361 accgcgcggg agttatcaat tagccccagt tcttcacaac cgttcagttt gaaggtatcg
    18421 aagccgattt cgcgtagcgt tttaatgccg tcgataacat ccgccggacg atcgccgccg
    18481 acccaactgt aggctttaat tttgtcgcga accaggccgc ccatcagttg ccagaccggc
    18541 gcattcagca ctttgccttt gatatcccat aaagcctggt cgatcccggc gatggcactc
    18601 atcagaatcg gaccgccacg ataaaatccg gcgcgataca tcacttgcca taagtcgttg
    18661 atgcgtgacg ggtcctgacc aatcaaatag tcactcagct cgtggactgc cgcttccacc
    18721 gtgcgagcgc gaccttcaat cacgggctcg ccccaaccga ccacgccttc atcggtttca
    18781 attttcagga acatccagcg gggaggtaaa cgatacgtgg taattttggt gattttcatt
    18841 gcactgcctc tcgatacgcc ttaacaaatg ctgctgcctg ctgcgcagtc cgttctacgg
    18901 actgcccggc gcgatagaga tcgctaccta agcccgctcc ggcacagcct gcatctatcc
    18961 actgcgccag gttttctggc gtcacaccgc caacggcaaa gaccgcgatg ttcggtggta
    19021 ataccgcttt taatgctttg atgtattgcg gaccaaaagc cgatgacgga aatattttca
    19081 gtgcctgcgc acccgcgtcg agcgcggtaa aggcttcggt cgccgtcgcg cagccggggc
    19141 agacggtcat gccgtagccc accgcacggc ggatcacttc actatggata ttgggcgtaa
    19201 cgatgagctg acagcccatt ctggcgagcg catcgacctg ttcaggtttc agtaccgtac
    19261 ctgcgccaat caacgccttg tcgccatacg catcaacgat ggcgggaatg ctctgctccc
    19321 attgtggaga attcagcggg atttcaaccg cgtcgaaccc ggcgtcaatc accgcgccaa
    19381 catgcgccag cgcctcgtcg ggcgtaatgc cgcgcaaaat ggcgatcagc gggagtttag
    19441 tttgccactg catgagcgat gttccttata ccagcctgaa atgccgtgtc gcccgccacc
    19501 gccgtcacgt cacaacccat cgcctgaaag gcttgctggt agcgcgcggt cagcgatgtt
    19561 ccggcgacaa gggtgatgac ttgttgatgg gccacatagt cgcgcatact ggcgacctct
    19621 gcgccaatca acaaaccaga gagaaattcg ctgacctgtt cgcggggaag tgttcccagc
    19681 acatgcgagg cgcgaacttc aaaaagctgt ggcaatacgg cgggcgcatt aaggccacgc
    19741 tcaagaccag ccgcgaaagc atcgacagcg ttttcctgcg gcggcaaacc tgcgccaatc
    19801 aatgagtgat ttaacagtaa atgatgtaat tcaccggtca tcacggtgcg aaaatcgtta
    19861 atttgctggc tatcggcctg cacccatttg caatgcgtac cgggcatgac ataaagagag
    19921 gaaggagcga gagtgcgcgc gccgatcaat tgtgtttctt cgccacgcat cacattgtgg
    19981 ttatcgtcat gagagacgca taatccggga ataatccaga tattgtcgcc aacagacgtt
    20041 aattgttcgc caatagacga aaaacgggca ggaatggata aatacggcgc aactttccag
    20101 ccgacattgc tgccgaccat tcctgccatt accactggcg tattctcttc acgccagtcg
    20161 gtcgtcactt ctgctaacac cgcagccgga gattttccat tcaggcgcgt gacgcctgct
    20221 tctgattgcc tgctgtccag gcagtggtcg ccctgataaa gccaggcgcg cagattggtc
    20281 gatccccagt caattgcgat gtagcgagct gtcatgtgat ttcctttaac cttcgtgtcg
    20341 agctggcgat catggtaagc gccgcctgct ctgccgcatc gccgtcctga tgccttatcg
    20401 catcgaacag cgccttatgt tcctggagcg tttgcggcat gttggcctca tcgcccatcc
    20461 aggttcgttc aaaaaccgcc cgctgcagcg aactgatcgc aatgctcagt tgttgtaaca
    20521 ccgggttatg caccgactgc agcaccgcct cgtggtagcg aatatccgct tcgttaaacg
    20581 cttcgcggtc ctgattgtta gcaatcatct cgttcagcgc cgattcaatc tgcgccagat
    20641 cgctggaggt cgcgcgctct gctgcccaac gggcaatagc cggctctacc aggtttcgca
    20701 cttcgctcat tgcactgata agccgtgggt catagtcgtt ttccagcacc cattgcagta
    20761 cgtcagtgtc gaggtaattc cactggttac gcggagccac aaacgccccg cgataacgtt
    20821 tcatttcaat cagccgcttc gccatcagcg aacgaaatac ctcacggatg atgttgcgcg
    20881 aggttgcaaa ctcctcacag agttctgcct cagccggaag cggcgagcct ggcacgtatt
    20941 tgccgtgaac gatctgttta cccagcgtaa taacgatgcg atcggtttta ttgagagtca
    21001 tggagagtcc ttgtgctctg tatgttcctc tctactttac cccgatcgat gcataacgcg
    21061 gcaattttgt agtaccagcg tgatgacgtt cgcgtttgct gtgcgcataa tgtagtacaa
    21121 atttatattg ttgtactaca atttagatca caaaaagaac aatccataag aaaatgttct
    21181 acgtcgggca aaaatctgaa aagggagatc aggcgctaaa caggagggaa agaagagtat
    21241 gctttcaacg gcttagcact cttgtttaaa ggattaatca tgaaattgaa ttttaaagga
    21301 ttttttaagg ctgccggttt gtgttctttg gcatttgcgt tgaccggatg tatcacctgg
    21361 ggattggttt ccaatactgc aagccgtcca catgccgagc aatggcggtc agacacgatt
    21421 aagggtttat cgctggctga agacagtaac ggtacgaaag gttatgtttt tgttggtgaa
    21481 tcgttggact atctattgac caccggcggc gatgaggtgg ttaacatgct gaacgatccg
    21541 gcaatccatg gtgaaagaat caccgtttct gataacgcga aatttatttt aagcagcagt
    21601 aataagaatt tctctggtgc tattacgctc tattacgact ggaacaacga agaagataag
    21661 gcactggcaa cacaatatgg ttttatttgt gatacccggc gttgtacatg gatgctggac
    21721 ggtttgaaag gctcaatcca ccagaaaaat aaaaaagcgg attactcaaa cgtgatggtt
    21781 ttccatcaac cctttacggt gggattttat gagtacaaag caacagatgg cgtcccgcgc
    21841 ggcctcgtta atgcgctgct gccagtcact cttacgctgg atatagtaac gtcaccactc
    21901 cagttcctga ttttatgcac gaccagaaat tgttaatcgc tgcgggcaaa cgcattcatg
    21961 ccgtttgccc gttcactgat taattcagca catacttctc aatagcaaat gccacgccat
    22021 cttcaaggtt agatttggtg acaaagttcg ccacttcttt caccgaagga atagcgttat
    22081 ccatcgccac accgacgcct gcatattcaa tcattgcgat gtcgttttcc tgatcgccaa
    22141 tcgccatgat ttcttccggt ttaataccta acacgtcggc cagtgatttc acacccgtac
    22201 ctttgttaac gcgtttatcg aggatttcga ggaagtacgg cgcacttttc agcacggtgt
    22261 atttttcttt cacttcctgc ggaatacgcg caatggcctg gtcgaggatg gcgggttcat
    22321 caatcatcat cactttcagg aactgggtat tggggtccat tttctccgct tcgcagaaca
    22381 ccagcggaat ggtggcaacg aaagattcat gcaccgtgta gtagctgata tctcggttgg
    22441 cggtgtacag cgtggtgcgg tccagggcgt ggaaatgaga accgacttcg cgagagagtt
    22501 tttccaggaa acggtagtcg tcatagctga gagcggtttg cgccacggtg ctaccatcag
    22561 cggccttctg taccagcgcg ccgttataag taatgcagta gtcgcccggc tgttccatat
    22621 gcagctcttt caggtaattg tgaacacctg cataagggcg acccgtcgtt agcacgacat
    22681 tcacgccacg ggcgcgagct gcggcaatcg catttttaac ggcgggtgaa atggtgtgat
    22741 cgggcagcag aagggtgcca tccatatcga tagcaatgag tttgatagcc atgagttccc
    22801 caggtagatt ggttcctgac ccatgctaac gcgattccgc tcaaaaatca gtacaacacc
    22861 cgagggaaaa ggggatgcaa cgcgcattgc gtgctcccca tttgcttagc ggaagagttt
    22921 ccctttcagc agttccatac ctgcggaaag cagatcgtta ttggcttgtg gtgacacttc
    22981 accttgcggt gagagtgcat caataatctt cggcaattgt tctgccagta aactggaagc
    23041 tgtactggta tccacgccaa gtttttgccc gagatcggac accgcatttg tgccgagcgc
    23101 cgattccact tgctcgccgc taactgattg attgctctgt tgattactca gccaggttga
    23161 gagaatggcc cctaagccgc cactttgcag tttttccagc agcacctgaa tgccgccctg
    23221 ctcctcaacc cagctcaaaa tcgcctgata tttccccgca tcgcctttca gaaaggcacc
    23281 gacaacttca tcaaaaagcc ccatgataat cacctgtaaa gcgttacgtg ttgacccaaa
    23341 aagtatagat ctgcgggatg ataattgcgg attgcaggaa taaaaagggc ggagatgatc
    23401 tccgcccgga ctgacgacta agtcatttta tcagcaacaa aaagccatta aatatcgata
    23461 ttcgccgctt tcagagcgtt ctcttcgata aacgcacggc gcggttcaac ggcgtcgccc
    23521 ataagcgtag tgaacaactg gtcggcagca atcgcatctt taacggtaac gcgcagcata
    23581 cgacggcttt ccgggtccat ggtggtttcc cacagctgtt ccgggttcat ctcgcccaga
    23641 cctttataac gctggatgga gaggccgcga cgggactctt tcaccagcca gtccagcgcc
    23701 tgctcgaagc tggctaccgg ctgacgacgt tcgccacgtt cgataaatgc atcttcttcc
    23761 agcaagccac gcagtttctc acccagcgtg cagatacgac gatattcgcc gccagtgata
    23821 aattcgtgat ccagcggata gtcagtatcc acaccgtggg tacgcacgcg aacaatcggc
    23881 tcgaacaggt tttgttcggc attggtatgg acatcaaact tccactggct gccgtgctgt
    23941 tctttatcgt tcagttcgct gaccagcgcg ttcacccagc gggtaacggt ttgctcgtca
    24001 gaaaggtcgg tttccgtcag cgtcggctga tagataagct ctttcagcat tgctttcgga
    24061 taacgacgct ccatgcggtt gatcattttc tgcgtcgcgt tgtactcaga caccagtttc
    24121 tctaacgctt cgccagccag cgccggtgca ctggcgttgg tgtgcagcgt tgcgccatcc
    24181 agcgcgatag agatctggta ctgatccatc gcttcgtcgt ctttaatgta ctgttcctgc
    24241 ttacctttct tcactttgta cagcggcggc tgagcgatgt agacgtgacc acgttcaacg
    24301 atttccggca tctgacgata gaagaaggtc aacagcagcg tacgaatgtg cgagccgtcg
    24361 acgtccgcat cggtcatgat gatgatgctg tgataacgca gtttgtccgg gttgtactcg
    24421 tcacgaccga taccacaacc aagcgcggtg ataagcgtcg ccacttcctg agaagagagc
    24481 atcttatcga agcgcgcttt ctcgacgttg aggattttac ccttcagcgg cagaatcgcc
    24541 tggttcttgc ggttacgccc ctgcttcgca gagccgcccg cggagtcccc ttccactagg
    24601 tatagttcgg aaagcgctgg gtcgcgttcc tggcagtctg ccagtttgcc cggcaggccc
    24661 gctaagtcga gcgcaccttt acggcgagtc atttcacgcg cgcgacgcgc cgcttcacgg
    24721 gcacgggcag catcgataat tttgccaacc acgattttcg cgtcggttgg gttttccagc
    24781 aggtattccg ccagcagttc gttcatctgc tgttcaaccg ccgatttcac ctcagaagaa
    24841 accagtttgt ctttggtctg tgaggagaat ttcgggtccg gcactttcac ggaaacgacc
    24901 gcaatcaggc cttcacgcgc atcgtcaccg gtggcgctga ctttggcttt tttgctgtag
    24961 ccttctttgt ccatgtaggc gttcagagta cgggtcatcg ccgcacggaa acctgccagg
    25021 tgagtaccgc cgtcacgctg cggaatgttg ttggtaaagc agtagatgtt ttcctggaag
    25081 ccatcgttcc actgcaacgc cacttcgacg ccaataccgt ctttttcggt ggaaaagtag
    25141 aagatattcg ggtggatcgg cgttttgttc ttgttcagat attcaacgaa cgccttgatg
    25201 ccgccttcat agtggaagtg gtcttctttg ccgtcgcgct tatcgcgcag acgaatggaa
    25261 acgccggagt tgaggaacga caactcacgc agacgtttcg ccagaatttc atattcgaac
    25321 tcggtcacat tggtgaaggt ttcaaggctt ggccagaaac gcaccatggt gccggttttt
    25381 tcagtctcgc cggtaaccgc cagcggggcc tgcggtacac cgtgttcgta gatctgacgg
    25441 tgaattttac cctcgcgctg gataaccagc tccagttttt gcgacagggc gtttactacc
    25501 gaaacaccaa cgccgtgcag accgccggac actttatagg agttatcgtc aaatttaccg
    25561 cctgcgtgca gaacggtcat gatcacttcc gccgccgata cgccctcttc cgggtgaata
    25621 ccggtcggaa tgccgcgccc gtcatcctgt acagagacag agttatcggc gtgaatggtg
    25681 acgataattt ctttacagtg acccgcgagc gcttcgtcga tagcgttatc taccacctcg
    25741 aataccatgt ggtgcagacc ggtgccgtca tccgtgtcgc cgatatacat acccgggcgc
    25801 ttacgcaccg catccagccc tttcaggact ttgatactgg aggagtcata agaattcgac
    25861 atcaacgttt ctcgctcatt tattcttggg ttaatccgtt attttaccct tttccacggt
    25921 aaacatcttc gaattttcgt ccgacatgtc tattacgtgt tcagcactga tcgcgctgac
    25981 aaagacctgt gattgcgtcg cttttaagcg gctggcaagc agcccgcgac gctcatcatc
    26041 aagctcagag gcaaaatcat ctatcaggta gagacaccgc cgcccgcttt cacgggtgag
    26101 gaactctcct tgcgccagac gtaaggcgca catcaacagc ttaagctgtc cacgcgataa
    26161 ggtatcttcc accggcgcac cgtcggcgcg aatgcgtaag tccgctttat gcgggccgtg
    26221 cgcggtgtag gttaactggc gatcgcgttc aaaattacgt tccagcacct cagcgtactc
    26281 tgtctctttc tcccagccgc gctggaaaga gaaagtcaga gaaaactcag ggagaaattg
    26341 cttacaggta tcagccatat cggctgcgat accggcgcta tactccgcgc gccaggtgct
    26401 gatttgctcc gccagcggga tcagttcttt atcccacggg cgtagctgtt cgtaacgagt
    26461 cacctggcgc agcgccgcat tgcgctgctt gagcaatcgc ttgagattgc tccaggcggt
    26521 gaaaaatccg ggttcgttgt gaaagcatcc ccagtcgagg aatgctcttc tgtatttggg
    26581 gccgccattg agtaaagtaa acccttctgg cgttatcagc tgcattggca tcaggtgcgc
    26641 cagctccgcg actttatgcc cgtctgtacc gtcaatacgg actttgctgt cgccttgttt
    26701 gtctttggtt aaaccaatcg ccgtctcacg ctcttcgccc tgtaatcgtc cgtggagaac
    26761 aaacgcctcc tgctcgtggc gaatgacgcg accaatctgc aaactgcgaa acgcccgacc
    26821 gtggccgagc gtatagatgg cttccagcac gctggttttg ccactgccgt tggcacctac
    26881 cagaaagtta aagccgggag ataaggcgag atccgcggtt tcaatgttgc ggaaatcgcg
    26941 gatcaacaag cgggtgaggg acattacagt ctcattggca tgacaacata agccgcgctc
    27001 tggctggccg catcttcaat ctgcacgctg gaaaccgaat cggtcagcat catgcggacg
    27061 ttttcgcatt tcagtgcgtt cagaacatcc agcacatagc tgacgttgaa gccgatttcc
    27121 atctccgcac cgctataggt aacgtcgagg atctcttccg cttcttcctg ttctgggttg
    27181 ttggcggtga ttttcagctg gttttcgctg acatacagac gcacgccgcg gaatttctcg
    27241 ttagagagaa ttgccgcacg ggcaaacgcc tgcttgagca gatcacagcc agcttccaga
    27301 tgcttgtccg ggttcttcgg cagaacgcga cggtaatccg ggaagcgacc atccaccagt
    27361 ttcgaggtga agataaagtc gccaacgtgg gcgcgaatgt tgttgctgcc aatctgcacg
    27421 cgcagcggat tgtcgccgcc gtcgagcata cgcatcagtt caattacgcc tttacgcggc
    27481 acgatcaccg aatggcttgg caaagattga ccaattggca ttgaacagac tgccagacgg
    27541 tggccgtcgg tcgccacggt gcgcagttct tcaccttcgg tttcaaacag cataccgttt
    27601 aagtaatagc gaacgtcctg atgtgccata gaaaactggg tcgcttcaat cagacgcttc
    27661 atcgtcgcct gcggcagggt aaattcgact tcgctctgcc agtcatcgag gttcgggaaa
    27721 tctgccgctg gcagggtaga cagcgaaaaa cggctacgcc cggagcgcac cagcatccgc
    27781 tcaccttcca gctgcacggc aatttccgcg ccttcaggca gaccacggca gatatcaaag
    27841 aatttgcgcg ccggaacggt cgtcgcccct ggttcgtgcg gctgaaccag cgcaacgcgt
    27901 gccaccattt ccatctcgag atcagtaccg gtcagcgaca acgtaccgtc agcaacctgt
    27961 aacagcagat taccgagaat cggtagcgta ggacgaccac ctaacggacc gctcacctgt
    28021 tgtagcggtt ttaataaatg ctcacgttct acggtaaatt tcataggttt acgatgacaa
    28081 tgttctgatt aaattagaaa aatcttcttt gatatcgtgg ctctcttcac gcaactgctc
    28141 gatcttccgg caggcatgaa gcaccgtcgt gtggtcacga ccaccaaagg catcgccaat
    28201 ctccggcaga ctgtggttag tcagctcttt cgccagcgcc atcgccatct ggcgcggacg
    28261 ggccaccgag cgggatcgac gcttggaaag gagatccgcg actttgatct tgtagtactc
    28321 cgccaccgtc ttctgaatat tgtcgatggt gaccagtttt tcctgcaatg ccagcaagtc
    28381 gcgcagcgcc tcacgcacga agtcgatggt gatcgcccgt ccggtaaagt tggcgttggc
    28441 aatgacgcgg ttcagcgcgc cttccaactc acgtacgtta gatcgtagac gcttggcgat
    28501 aaagaacgcc acttcgcccg gcaaacgaat gtcgttttcg tcggcctttt tcatcaggat
    28561 cgccacgcgg gtttccagct ctggcggttc gatcgccaca gtcagtcccc agccgaagcg
    28621 ggatttcaaa cgatcctcaa cgccgttgat ctctttcgga tagcgatcgg aggtgagaat
    28681 gatctgttga ttaccttcca gcagggcgtt gaaggtgtgg aaaaactctt cctgagatcg
    28741 ttctttatta gcaaaaaact gaatatcgtc gatcagcagt gcatctacgg aacggtagta
    28801 gcgtttaaac tcttcgatcg cgttgttttg cagggcttta accatgtcct gaacaaagcg
    28861 ctcggagtgc atataaacca ctttggcatt cggcttgcgc gccataatgc cgttacccac
    28921 cgcatgcagc aggtgagttt tacccaaacc cgtgccgcca taaaggaaca acgggttata
    28981 agcaccgcca gggttatctg ccacctggcg agccgccgcg cgcgccagtt ggttagattt
    29041 accttcaacg aagttatcaa acgtgtgttt gacgtttacg ttagaacgat aggtcggttc
    29101 tgccggagcc gggacgttat cccaacccga gcgcgtagaa ggcgcagcac gttgcggctg
    29161 cgtttgcgcc acctgtgcag gggccgcgac gttgctcgtc actgccgctt gtggcgtttg
    29221 cgtcaccggt ttggtgccga cttcaaaacg cagctgtggg gcatccgctc cgcagaaact
    29281 ggttagcagt ccattgatat tattaaggta cttgtcccgt acccaatcga ggacaaaacg
    29341 gtttggcgcg tacagggcca gcgtgttatc gctcagttcc gcctgcaatg ggcgtatcca
    29401 catactgaat tctgtggctg gtaactcatc ctgcaatcgg gcaagacact gctgccaaag
    29461 cgaaagtgac acggcggact ccactcgaac aaaagtcgat aatgactaag gctgaaacat
    29521 tcatgattgt tgacgtacgt cgaaaagacc ctgcatgagg gtgacgcacg aaccgctgtc
    29581 tgcggttata tgcccgatca agatcctgca aaacgatcgg gaccgcggat catagcctaa
    29641 actgcgcaag agatcttctg tttctcacag attttcccga tttatccaca ggatgatcca
    29701 gaactcgcta agtgtaaacg atcctgccgc aggccgggca cgatttacgc cgcatattgg
    29761 aaaatttaat gaccatagac aaaaaatggc ttaatcgatc taataaagat ccaggacgat
    29821 ccttgcgctt tacccgtcag cccgtataat cctccacccg gcgcgccatg ctggttttca
    29881 ctggtgtgag gccgtacgtt ttccccgcga aaaggtgcgg aaaagcgcgg taaataagga
    29941 aagagaattg actccggagt gtacaattat tacaatccgg cctctttaat cacccatggc
    30001 ttcggtgtcc atcgtttcat ttttcggcgg atatccaata aagccattga atttattcaa
    30061 gtttaggtag aaatcgccat gaaacgcact tttcaaccgt ctgtactgaa gcgcaaccgt
    30121 tctcacggct tccgtgctcg tatggctact aaaaatggtc gtcaggttct ggcacgtcgt
    30181 cgtgctaaag gccgcgctcg tctgaccgtt tctaagtaat aaagctaacc cctgagtggt
    30241 taagctcgca tttcccaggg agttacgctt gttaactccc agtcaattca cattcgtctt
    30301 ccagcagcca caacgggctg gcacgccgca aattactatt ctcggccgcc tgaattcgct
    30361 ggggcatccc cgtatcggtc ttacagtcgc caagaaaaac gttcgacgcg cccatgaacg
    30421 caatcggatt aaacgtctga cgcgtgaaag cttccgtctg cgccaacatg aactcccggc
    30481 tatggatttc gtggtggtgg cgaaaaaagg ggttgccgac ctcgataacc gtgctctctc
    30541 ggaagcgttg gaaaaattat ggcgccgcca ctgtcgcctg gctcgcgggt cctgatagcc
    30601 ctcattcggg tctatcaacg cctgattagt ccgctactcg ggccgcattg tcgtttcact
    30661 ccaacctgtt caagctacgg aattgaggca ttgcgcaggt ttggagtgat aaaaggcagt
    30721 tggttgacgg tgaaacgcgt attaaaatgc caccctttac accctggtgg tgacgatccc
    30781 gtcccgcccg gaccatttga taccagagaa cactaacgat ggattcgcaa cgcaatcttt
    30841 tagtcatcgc tttgctgttc gtgtctttca tgatctggca agcctgggag caggataaaa
    30901 acccgcaacc tcaggcccaa cagaccacgc agacaacgac caccgcagcg ggtagcgccg
    30961 ccgaccaggg cgtaccggcc agtggccagg ggaaactgat ctcggttaag accgacgtgc
    31021 ttgatctgac catcaacacc cgtggtggtg atgttgagca ggccctgctg ccggcttacc
    31081 cgaaagagct gaactctacc cagccgttcc agctgctgga aacttcaccg cagtttattt
    31141 atcaggcaca gagcggtctg accggtcgtg atggcccgga taacccggct aacggcccgc
    31201 gtccgctata taacgttgaa aaagacgctt atgtgctggc tgaaggtcaa aacgaactgc
    31261 aggtgccgat gacgtatacc gacgcggcag gcaacacgtt taccaaaacg tttgtcctga
    31321 aacgtggtga ttacgctgtc aacgtcaact acaacgtgca gaacgctggc gagaaaccgc
    31381 tggaaatctc cacctttggt cagttgaagc aatccatcac tctgccaccg catctcgata
    31441 ccggaagcag caacttcgca ctgcacacct tccgtggtgc ggcgtactcc acgcctgacg
    31501 agaagtacga gaaatacaaa ttcgatacca ttgccgataa cgaaaacctg aacatctctt
    31561 cgaaaggtgg ttgggtggca atgctgcaac agtatttcgc gacggcgtgg atcccgcata
    31621 acgacggtac caacaacttc tacaccgcta atctgggtaa cggcatcgcc gctatcggct
    31681 ataaatctca gccggtactg gttcagcctg gtcagactgg cgcgatgaac agcaccctgt
    31741 gggttggccc ggaaattcag gacaaaatgg cagctgttgc tccgcacctg gatctgaccg
    31801 ttgattacgg ttggttgtgg ttcatctctc agccactgtt caaactgctg aaatggatcc
    31861 atagctttgt gggtaactgg ggcttctcca ttatcatcat cacctttatc gttcgtggca
    31921 tcatgtaccc gctgaccaaa gcgcagtaca cctccatggc gaagatgcgt atgctgcagc
    31981 cgaagattca ggcaatgcgt gagcgtctgg gcgatgacaa acagcgcata agccaggaaa
    32041 tgatggcgct gtacaaagct gagaaggtta acccgctggg cggctgcttc ccgctgctga
    32101 tccagatgcc aatcttcctg gcgttgtact acatgctgat gggttccgtt gaactacgtc
    32161 aggcaccgtt tgcactgtgg atccacgacc tgtctgcaca ggacccgtac tacatcctgc
    32221 cgatcctgat gggcgtaacg atgttcttca ttcagaagat gtcgccgacc actgtgaccg
    32281 acccgatgca gcagaagatc atgaccttta tgccggtcat cttcactgtg ttcttcctgt
    32341 ggttcccgtc aggtctggtg ctgtactata tcgtcagcaa cctggtaacc attattcagc
    32401 agcagctgat ttaccgtggt ctggaaaaac gtggcttgca tagccgcgag aagaaaaaat
    32461 cctgattcgg tgagttttcg ctaaaataag ggcggtcagt tgaccgcctt ttttcttttc
    32521 gtagggcgga taagcaccac acatccgcca cacaaagcaa caggaacatc atgagcgata
    32581 atgacactat cgtagcccag gccacgcctc cgggacgtgg cggcgttggc atcctgcgca
    32641 tctccggcct caaagcccgt gaagttgccg aaaccgtgct gggtaaactg cctaagccac
    32701 gctacgccga ttatcttccg tttaaagacg ccgatggcag cgtgctcgat caggggattg
    32761 cgctatggtt ccctggcccg aactcgttca ccggcgaaga tgtgctggaa ctgcaaggtc
    32821 atggcggtcc ggtgatcctc gacctgctgt taaaacgcat tctgaccatt cccggcctgc
    32881 ggattgcccg ccctggtgag ttttccgaac gcgcatttct gaacgataaa ctcgacttag
    32941 cccaggccga ggcgattgcg gatcttatcg acgccagctc ggaacaggcg gcccgttcgg
    33001 cgctaaactc gctgcaaggc gcgttctccg cacgggtcaa ccatctggtg gaagccctca
    33061 cccacttgcg catttacgtc gaagcggcaa ttgatttccc ggatgaagag atcgatttcc
    33121 tctccgacgg caaaattgaa gcccagctca atgacgtaat tgccgatctc gacgcggtac
    33181 gcgccgaagc tcgtcagggt agtttgttgc gcgaagggat gaaagtggtg attgccggac
    33241 gtcctaacgc cggtaaatcg agcctgctga acgcgctggc gggccgtgaa gcagcaatcg
    33301 taaccgatat cgccggaacc acgcgtgacg tgctgcgtga gcatatccac attgacggaa
    33361 tgccgttgca tatcatcgat accgccgggc tacgtgaagc cagtgacgaa gttgaacgta
    33421 ttggtatcga gcgcgcatgg caggaaattg aacaggcaga ccgcgtgctg tttatggtcg
    33481 atggcaccac gacagacgcc gttgatccgg cagagatctg gccggaattt atcgcccgtc
    33541 tgccagcgaa actgccgatc accgtggtgc gcaataaagc cgatatcacc ggcgaaacgt
    33601 tggggatgag cgaagtgaac ggtcacgcgt taattcgtct ttcggcgcgg actggcgaag
    33661 gcgtggatgt gctgcgtaac catctcaaac agagcatggg ctttgacact aatatggaag
    33721 gcggcttcct ggcgcgtcgt cgtcacctac aggcgctgga acaggcggca gagcatttgc
    33781 agcaaggtaa agcgcaactg ttaggtgcct gggcgggtga actgctggcg gaagagttgc
    33841 gcctggcgca gcagaactta agcgagatca ccggggagtt tacttcagac gacctactgg
    33901 ggcggatttt ctccagcttc tgtatcggta agtaaccgcg cttgcgaagc cgcattctga
    33961 ctgtcagatg cggcttcgct tcattgttag cactcctgtt attcctcaac ccttttttaa
    34021 acattaaaat tcttacgtaa tttataat
//
LOCUS       DAPOXO010000054        33775 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPOXO010000054 DAPOXO010000000
VERSION     DAPOXO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33775
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.054"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(69..818)
                     /locus_tag="ROH59_003010"
                     /pseudo
     CDS             complement(69..818)
                     /locus_tag="ROH59_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426061.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein finQ"
     gene            1047..1364
                     /gene="sugE"
                     /locus_tag="ROH59_003011"
     CDS             1047..1364
                     /gene="sugE"
                     /locus_tag="ROH59_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDX4805463.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIA
                     MLSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKL
                     STH"
     gene            complement(1361..1894)
                     /locus_tag="ROH59_003012"
     CDS             complement(1361..1894)
                     /locus_tag="ROH59_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HDX4805464.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIAT
                     REGFEVNKLIWVKQPGA"
     gene            complement(1988..3133)
                     /locus_tag="ROH59_003013"
     CDS             complement(1988..3133)
                     /locus_tag="ROH59_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C beta-lactamase CMY-2"
                     /protein_id="HDX4805465.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQA
                     IPGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGE
                     IKLSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQP
                     QWTPGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKD
                     YAWGYREGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQ
                     SRYWRIGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVH
                     KTGSTGGFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
     gene            complement(3457..4719)
                     /locus_tag="ROH59_003014"
     CDS             complement(3457..4719)
                     /locus_tag="ROH59_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEc9 family transposase"
                     /protein_id="HDX4805466.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDS
                     TNKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFK
                     TTQMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYN
                     IQFAFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEK
                     IIETIESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRF
                     VVSRVLKPEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKY
                     DMAVGHLLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAA
                     KIIKTARYVIMKLSENYPYKGVYEKCLV"
     gene            complement(4905..5252)
                     /locus_tag="ROH59_003015"
                     /pseudo
     CDS             complement(4905..5252)
                     /locus_tag="ROH59_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426061.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein finQ"
     gene            5567..5719
                     /locus_tag="ROH59_003016"
     CDS             5567..5719
                     /locus_tag="ROH59_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001618166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HDX4805467.1"
                     /translation="MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATL
                     AYEVKR"
     gene            complement(5791..6042)
                     /locus_tag="ROH59_003017"
     CDS             complement(5791..6042)
                     /locus_tag="ROH59_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805468.1"
                     /translation="MSEKWSKEFDSCFQVGSIEEIADALEKRSGSEENALAMLAMTAF
                     TLMTRRGICEMQNVAPDGKGIRLELIGFRENETIPDTLH"
     gene            6342..6638
                     /locus_tag="ROH59_003018"
     CDS             6342..6638
                     /locus_tag="ROH59_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011264046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805469.1"
                     /translation="MSALRHVLSDILFSGKNRLQVLAKTSGGAGFGALVGEELSITDT
                     IETVVTGSVRANNGVLSPVMEKRMINLLIIVLRAVVAVANALIAVLELIRELID"
     gene            complement(6703..6879)
                     /locus_tag="ROH59_003019"
     CDS             complement(6703..6879)
                     /locus_tag="ROH59_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805470.1"
                     /translation="MNLVDAFVKKVISEPYEEYGKWWIDVEYISWGVPGKTRLMFESK
                     EQALEVKEGYKFLT"
     gene            7271..7480
                     /locus_tag="ROH59_003020"
     CDS             7271..7480
                     /locus_tag="ROH59_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDX4805471.1"
                     /translation="MSMPPAIANTFLFEMMKSKSKDVTLAAIYALGEGRCQAENITRE
                     LHRLSQSDDMEIKIAAIKALGRIYR"
     gene            complement(7552..8214)
                     /gene="excA"
                     /locus_tag="ROH59_003021"
     CDS             complement(7552..8214)
                     /gene="excA"
                     /locus_tag="ROH59_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid IncI1-type surface exclusion protein
                     ExcA"
                     /protein_id="HDX4805472.1"
                     /translation="MKAKKETTDRFPTWWLFYYVLRKAYFFLGIPFFLFCALGFTEML
                     CSDRYFGNKVEDYVVTFGSWFLLLAPGIWMYSRAKTRREKIRKVVQTIKESGFYSPEK
                     GYEGLSLTQGAYFGIDLKNGTMLYVRIYPGNIMDVIGFDIHNFTRTVTDDKTLEIHTK
                     YINLPMVPIPSWCTHPETASNTMHAMASRGYDYPVDFPRLIQEKRKEWEQIAGIPVAE
                     VF"
     gene            complement(8285..10453)
                     /locus_tag="ROH59_003022"
     CDS             complement(8285..10453)
                     /locus_tag="ROH59_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotA/TraY family protein"
                     /protein_id="HDX4805473.1"
                     /translation="MKILLRALCAGLAISSLPAMASVTYQDIVSAATNPDDLSRQALV
                     TIFGDVVTNPLSTSAPTLIGSMFGAFNSIIAVLAVVWFMFIGIRHVVRSGHQGQVFST
                     GRDIVGTLSVVAGFLMIVPTGNGWSIAQLIMLWGASIMGVGSANVMVQLAADNIANGY
                     SMTVQPVQASTRTAARGIFEMELCKYAVNAGLNDFNQTAKSSTSLMTESAKTASGNYT
                     VTVSNGSGICGSASLSVEGNGTTDQSTIGKFFNPFSKNEYSGVISAQRAAMDNMISDM
                     DNAASEFVTTFLEKRNSGNGTLPDIETRIQRAADEYERAVQKSLPTDNGEQSRKEALK
                     SYLTTYGWVTLGAWYQTFATANQRLAELADRAPAVTSMSSLGEVGDTDLFSAVMSAYR
                     TQLQNSSYTPPLGTVVSSSEQRMANAQDPKSALSEIMGPLVSLTNRIATETSGTGTTS
                     AQINPLIKMKNIGDITMVSAEGIWTIYTTARVVVAGGKDSILVKFFNSLTGAASMLTA
                     LFEALAPPVYFLLFLMFCAGFSLSIYLPFIPFIFWMTGIGNWIVSVLIGCTAGPLWAA
                     THLGTSEDRGSRAAYGYIYLIDSMIRPPIMVFGFFFASVAIIAVGTILNALFGAALVN
                     VQFNSLTGIFSLAGFLLIYARICTTTVAAIFALQAYLPDHVINFLGGRDGANTLGSMA
                     NSVKEIFIGGSRNIRHTPGMKTDRLKDNTKGSDDKDGIKG"
     gene            complement(10550..11134)
                     /gene="traX"
                     /locus_tag="ROH59_003023"
     CDS             complement(10550..11134)
                     /gene="traX"
                     /locus_tag="ROH59_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraX"
                     /protein_id="HDX4805474.1"
                     /translation="MNKLPENSDQTKNVKKSPSITRIATRRIINIFVPLMETRLITNS
                     VQHMLKQQKSRLEKFRQVNNKKAQLCLSWEEALQASHMSVDDLDRRFRRRRTVWRFCC
                     WSLLAIALFLSGMLFAASSLPLTTLVRAISTLVLILSGVALCASRALIVTYRLWQLHE
                     RKVSEPEQGTFRDFLNDRNGWRNATLIAVTSKQY"
     gene            complement(11163..12365)
                     /gene="traW"
                     /locus_tag="ROH59_003024"
     CDS             complement(11163..12365)
                     /gene="traW"
                     /locus_tag="ROH59_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraW"
                     /protein_id="HDX4805475.1"
                     /translation="MQRKTLLAALIATLSGTACQAHAYSVTVVASRPVEEQVIPRMEA
                     IKDVLGNILSTQTATGTAINQNSEKLASVIAQNGQATRQQMIFSNETQRLEEARKSFT
                     VPDSICSESASGIATESKSASASAASKLSKGGGVSNRSIRDRLASAANSPVREAYDGA
                     AIHASYCTEAEYARFGGTAVCPSVGEIPGGDSQVRSIYHGAGTADTPAALTWDQKQID
                     AATAYMKNTSRPSAGRALGKGEVNTQSGRTYVGLQNEYNGIIDSASNPQLTLIADSTP
                     NESTRKALAETLQSDSAAAYFDQVASPEAKARGYMSTREFEAFEAGRRYANTAYLVDL
                     QEMQGDNLLRELVRITAQMNWQLNDLKEQIRQGNVISGQQLALTARQYYEKQLGSLEK
                     TINQANAR"
     gene            complement(12332..12946)
                     /gene="traV"
                     /locus_tag="ROH59_003025"
     CDS             complement(12332..12946)
                     /gene="traV"
                     /locus_tag="ROH59_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraV"
                     /protein_id="HDX4805476.1"
                     /translation="MCTIHITPRCRRPARGQVFLKKLEVKGDSFSFTLPSRVFRLHPA
                     PNPRVIYASDARTQGKVTGMRLLLPSSTDELITTAIWQVSVPDEAPFDVQHVIQWILP
                     SPLASLMSDDTWLWPSVPGTPALSAGDWPVMDTDPSTLRRVRRRSFSIIDNRNRKGYI
                     TRRYQCFPLAPLPEDRKYDSLPDLVLHPEQETIKCKEKHYSQPL"
     gene            complement(12946..15990)
                     /gene="traU"
                     /locus_tag="ROH59_003026"
     CDS             complement(12946..15990)
                     /gene="traU"
                     /locus_tag="ROH59_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraU"
                     /protein_id="HDX4805477.1"
                     /translation="MNINRLIFTIEDCLNTLSRFSVASSFVEYCDLRTVIGLDRQDRE
                     RRPWLNSPYIAATKRGEYLSVFEVSGAFREMDEASDQTGPGSLESLITSMSDSLNTAY
                     KNSGHKISCVFERDPDMGKEEIEDMVAPQKRSLANTGIQLQDVVDEKVTTLSPWLVRE
                     RCWLAIWSGPDLISNSDRTAHDELVRRLAERVPKARFAQSPWQWTLSALKIRHEAFLD
                     NVEQALRHSSDGLILRLLDIHEVGREIRRQTERHSTPRNWQPHLPEDAQPAGYRWTDD
                     ESVLHAPSLHLQLFNTQVTTQGNLVQAGGLWHGMVSITLPPQNLQTFNELVRAVPRAV
                     PWRIRMDLMPGGMKALNLKKTLLTYSSFISAVRPMYESVMTLAATDEKEPVCIMTIMA
                     STWGKTREICTRNQAILKSAIEGWGVCGTTTTFGDPRRAWVNTILAASGGSGPVPLYP
                     PLSHAISLFPLNRAGSVWRGKGNLMLHTEDGSAFEVGLASSQQNKHTELAPGDPGLGK
                     SVLINTLSEIQISSAQKNLPFIAYIDKGYSAQGLVQLIRDSLPPERKDEAVGIILSND
                     PEYTRNLFDVMYGAKKPITPEKNFMSSVLCALCVDTGTGQPCNPGDTRQIINQLIELA
                     FKEYGENNPRLYRASTEDLVDSALQDSGLYEKHDAAWWARSTWFEVRDMLHNAGYIMA
                     AQRAHYQAMPQLPEVSSMLGHTSLRDVFGTVQRDGSNELLLDYIRRALEQGHNDYPMI
                     SGYTRFMINPETRVIAVDLNNVAGDKTPAGRLKTGIMYLLAGQIAGGDFTLPQYRDEV
                     LKQLPREYHEIALKRINQLDQEVKTKVYDELHNARGIDFIWENLDTQEREQRKFAIRT
                     VLSTQYLRDYPESVLKSANTLWLLRYKPEDIPVLRDNFNVPEFMLKRFLKMPEGPAPD
                     GSGVPVLGVFRVKSGTLARILKFTVGPLELWALNSSPKDSALRKTLTNKLGSVRARKI
                     LAENFPRGSATSLIEHRAGQHNSDNVIEELASELIRKQGYNL"
     gene            complement(16080..16880)
                     /gene="traT"
                     /locus_tag="ROH59_003027"
     CDS             complement(16080..16880)
                     /gene="traT"
                     /locus_tag="ROH59_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001164783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraT"
                     /protein_id="HDX4805478.1"
                     /translation="MQHSIKDLWLYPFPEIDVVHTQEPLLPEPELTTPGRCICCRQNV
                     RHRFRLDDSWPLRQLTDTISDTRVRLNKATEHLDKLKKRGEPVATGEKEKYNTAVKAA
                     ERALEQARLSARRLSLRHVQKAEITSTESLSEKEQELFHEDGPPYSLCAFCHAWHSLN
                     GYAAAQGVMVWLPDLHPSTVVALNRRSLQEVFSNDKFRVRRGREALSALMQNRLAVED
                     KFRSFRPADFADVFRRYPPSGRSPLREKMNGIALILTPDSFIKKEYVD"
     gene            complement(16864..17052)
                     /gene="traS"
                     /locus_tag="ROH59_003028"
     CDS             complement(16864..17052)
                     /gene="traS"
                     /locus_tag="ROH59_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conjugal transfer protein TraS"
                     /protein_id="HDX4805479.1"
                     /translation="MSAWSPEHITLRRTENGNVIAHDSRDDQEFIFAECCSDEIANII
                     LEAVKRYTSTEPAHATQH"
     gene            complement(17116..17520)
                     /gene="traR"
                     /locus_tag="ROH59_003029"
     CDS             complement(17116..17520)
                     /gene="traR"
                     /locus_tag="ROH59_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraR"
                     /protein_id="HDX4805480.1"
                     /translation="MSRIRVVAARLYAAFIHAQLFVMSCRSKLTKYLLLIPMMLLPKA
                     VLADGDLADMVRNVGEGAKTAQSSSITIAQFIGVILFLGGLIGLKKVGKQGGMGLAGC
                     IVSIVIGAVLVAGPEMMSRSQKQLGISSISIG"
     gene            complement(17571..18098)
                     /gene="traQ"
                     /locus_tag="ROH59_003030"
     CDS             complement(17571..18098)
                     /gene="traQ"
                     /locus_tag="ROH59_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraQ"
                     /protein_id="HDX4805481.1"
                     /translation="MNMDALTAIENFASSIFSAGMDFLFTWGEFIGVISMITLFARAR
                     SAGPVKMSPGKFIAGMLTSCMLVSLPAMINAGGVQMGFRADSFGPIAYVQPQTFGAAA
                     GAANAVLSLAKLAGVGFVMNGISIWRKAGLDGHTALSASESVSKGNVKFIAGVLLVFI
                     DRVLNALLASIGIVF"
     gene            complement(18098..18802)
                     /gene="traP"
                     /locus_tag="ROH59_003031"
     CDS             complement(18098..18802)
                     /gene="traP"
                     /locus_tag="ROH59_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraP"
                     /protein_id="HDX4805482.1"
                     /translation="MKPETEIDETGSFGEPEEKPAPFWKRSVWGISVATWGLCAVVLL
                     AAIWYLFLRAPSETGMPSFNDADAGVQTWQTTQESSPSVQSTETMTVRTGEDMSQLAR
                     DVKTELDNRDEKIQATLNMLHDSINKLGEAIKKDEEYAQETRRQLDDIRSRLNGIMTQ
                     KSVTESSSTPHPAKKKTSSVLNGMKIMSMETGMAWIRWQGSTWAVREGQTLGNVVIQR
                     IDPTTRTIITSAGTLR"
     gene            complement(18802..20091)
                     /gene="traO"
                     /locus_tag="ROH59_003032"
     CDS             complement(18802..20091)
                     /gene="traO"
                     /locus_tag="ROH59_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraO"
                     /protein_id="HDX4805483.1"
                     /translation="MSAEQDAGKSGKKLAALLGLGSIILFGGGYIAFSKLSGSNSDMQ
                     SAVNINSAASGGTRSVTETPHYRELLRADNERGAAAAARNNQTFIASLPQGLDIPDTP
                     EKQQQPATKPENYAHRQASGTPQEDRAASEKRMERLQKLIVRIKDQHPAGSTPTIATT
                     MWNKSPAETTGQNGTQQFALQNASLSTPVAEKGIQLIPALTRIPAYIDTAVDSDNPSS
                     KVIATIPAGPWAGATLFSPGVKLVGNGVEIHFDRMSWNGMDLKVNAYAQREDNLMSSV
                     ASNVNTRWFKHIILPSVLGGVGSIGTLYKDANTQVIQGNYGTVTGRVGMPSGEAVAGV
                     IAGGMAERGSQILTRQAESEPYKQVEVYQHEVVSILFVDPVMTNDARSSSLSSGISPS
                     VNRTSQAEQRSQARMQTAMEQRKAVMQRRYDEQPETP"
     gene            complement(20094..21077)
                     /gene="traN"
                     /locus_tag="ROH59_003033"
     CDS             complement(20094..21077)
                     /gene="traN"
                     /locus_tag="ROH59_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001191879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TraN"
                     /protein_id="HDX4805484.1"
                     /translation="MQSRYLLSTLLLVCSAATSADNAGWQNARTPQTTNSASDHVQNA
                     SQNTGGVPATLVKGELPAPGQASPLVQDAARLDSELSADEIRSLRSLMADNERAINAP
                     ITSVVPRISSLTVNLSPGASLPLVRTAMNNLSVVTFTDINGSPWPQSDPPYNAAPKLF
                     DVQYNGNMVTITPLRPWASGNISVYLKGLSVPVILNVTSGETDTPSSSQEMDSRLDLR
                     IPRQGPTSPVVSIPTDKIALHDATLQAFLDGIPPRDPSVKRLKFTGNVPDTTIWQHGD
                     DLLVRSRAMLRDEFEQTLSSADGTHLWKLPVTPLLTFSVNGQSVHVTPELE"
     gene            complement(21088..21780)
                     /locus_tag="ROH59_003034"
     CDS             complement(21088..21780)
                     /locus_tag="ROH59_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotI/IcmL family type IV secretion protein"
                     /protein_id="HDX4805485.1"
                     /translation="MTENTEPSSPSHPAPDPEILKSTIRAMKQSEQRANNVPALIKAL
                     LCTGTCLLISITGNAIQYWHSTNVEREYFATDNGRLVRLAPTSQPAWSQNDAMAFGSQ
                     ALATAFNLDFVHYRSQISSLSPRFSDEGFVGYVNALQASNILETIKKEKMNLTATTGA
                     GVLVRQGQMSDGVWFWTFQYPVRMRLVGQTTSKPEQSFVFEITIQRVDPRLKPSGMEI
                     RQMISRNAGPNS"
     gene            complement(21777..22124)
                     /locus_tag="ROH59_003035"
     CDS             complement(21777..22124)
                     /locus_tag="ROH59_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001629514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDX4805486.1"
                     /translation="MNMHKSLVAVLGLILISSTASAATCRAGSAAQAGSNTGYERARA
                     AADAWSQRENDVSSSLQSCLSRIKKISINLPQFPSLDDILSQLENQVCDAVVDKVNEK
                     LPGNIDPWKDYNL"
     gene            complement(22142..25909)
                     /locus_tag="ROH59_003036"
     CDS             complement(22142..25909)
                     /locus_tag="ROH59_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDX4805487.1"
                     /translation="MPSVSRYRTWLAVPADEIEDLKKAHPPMNGHTPVLWDKEHKLWF
                     ARPGADLSMLDRWLPRPQEVSMNGSDPVTEFAQVLENAGLVLKELPVMDGKIHRVPTA
                     GDKKGQKSGAYRGFLDGRPAGWYRDYRSADDSPVTWTFSGGEQTDPRARLHLKAHSMQ
                     RREDAERELKAQYNRQAAYARRYVSKWPQATAHEYLTRKGIQAAPGVRINDKNELVIP
                     FSNRNGAIRSYQRIPVTGGKDARILKDSEKTGNWFALGTPRNGQPVLFAEGYATAASL
                     HEATGLPVLMTVDAGNMIIVAEEARQKWKQSPFIFCADNDHARQVNKGIVSATKAAEL
                     TGGSVIFPAFTDAEKAQGLTDFNDLDASRGRAAFLHVINAQLEHIGVSTPNSNTPEIR
                     EALVIGNLVFTPVHTEEKTMTPTEYPETSPDTGHSHDQGPSLPSATQQEQPAASSSNI
                     ADETQSFTSHATENNGKDERHADNVQAQTESSVVQDSPAESPASPESTTASAPDEPAH
                     PAEPPEKVVSVATDKDWREFEAELSQPEKNESQQESGTSPEIPAPAAAPASPEDSPSS
                     ETMNESAEPSPSPDAVKEEMTVMTEPDDKQSIGISPDTPREEAVNHVTEDIPLQPEPF
                     LPESDGPEEYEDYSAYQELMNNENPEHLQENSDMPSQPDTGHVQADESELQATTATIE
                     PAVRDEPTPQQPVQSTSPSDNTSSFLDKARGFFTRKKTDSQAHENSDPTPSAETTTTP
                     PIPDSIVYAPERSDAPISLNMDEILKELDWEKRADRTVLYKLDGKPAFIDRVNRLEMV
                     NGASNDDRSVLAALAVATKFYGGVIELTGSDAFKQKAMQLIIEHNIDVRMKLPDQRAE
                     LEKLRKEMAVSKDAVVTHQPTPELNRNIPEQPAVPDPVQEKEATQSPASPAAPEASTV
                     STAPASSPAEPGKTADAAPGEEPPGKLRPGESVTAVLHNFGRAEYAPGKGESFFVELK
                     NRSGSKLYWGEQLESLVKNHQKGDVVTLTLQNREQFILPGEQKARFRNKWSMESVTNG
                     ISVSHDNPDKGQRIQAIPVETFMKVAAQISQGWPEEMKALRMPENVGSHLFIGEDRHP
                     VSAPQNANQVTEITSAAPDKLTPVLGSVDKDTRELNLLLVQSADEHLQGVVRLNGTLY
                     PALATPSADNSQLVINALTDKGLRFAGYGEAVNHDADSTNRPAPELMQFHLKTREEPL
                     FAAVYTPEKQPDALYRNLGFEQSWQQWSNSQKPEDRQEKTLHQDLSHSPGR"
     gene            complement(25999..26550)
                     /locus_tag="ROH59_003037"
     CDS             complement(25999..26550)
                     /locus_tag="ROH59_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HDX4805488.1"
                     /translation="MSGKKTIVTLLRVSLLACPLLFTTPSFAMIDTPSVKVGFSPEGS
                     ASALVLDTINSAESSIRMMAYSFTDPDVMHALAKAKKRGVDVRIVVDDKGNTNRASQE
                     AMKYINLLDIPLRTVDAFPIHHDKVIIVDGNTVETGSYNFSRAAARKNSENVVVLKNM
                     PDVAAQYLEHWQDRWNKGTDWRP"
     gene            complement(26565..26855)
                     /locus_tag="ROH59_003038"
     CDS             complement(26565..26855)
                     /locus_tag="ROH59_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDX4805489.1"
                     /translation="MKREGFWRYATPPVNIQGVPLPFTMIYLFICPFPSKTTFWICTG
                     IILFFVILDRSGWTVRTICTRIFSILRGAIASGRPWWYRHHTESPRDWTGLD"
     gene            complement(26852..28000)
                     /gene="traJ"
                     /locus_tag="ROH59_003039"
     CDS             complement(26852..28000)
                     /gene="traJ"
                     /locus_tag="ROH59_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid transfer ATPase TraJ"
                     /protein_id="HDX4805490.1"
                     /translation="MNIPDEFGLFPFQRFTADELRHFFVWCAAHKVSDVDLTGGSPVS
                     VSRFGRRVRCSSATLPTTLMSSLIDELFGREVIPRVLAGNPVDRTIQINGDASGRYGL
                     KRGERIRLRSHLIQGTSGAEEKAISITMRVIPTEIPDILSMNIEPDLLEAMVCKSGLG
                     FVCGETGSGKSTLCSALYRYIMDNFPDAKIVTYEDPVEYILGNENDLLPPHQAEIGRD
                     VVSFAAGLRSAVRRNPEIIGVGEIRDNETADAAVQAGNTGHYCLSTMHTKSPGETLAR
                     LLGLFPPVIRDSMAWAVLSLLQFILVQVLVRTNDGGRKAVREYIVINDELRDNLSGMP
                     HAEWGHHIDAIIRQEKRRIRDQILEMYIRNEVDRREAILFIPPGELRS"
     gene            complement(27997..28815)
                     /gene="traI"
                     /locus_tag="ROH59_003040"
     CDS             complement(27997..28815)
                     /gene="traI"
                     /locus_tag="ROH59_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer lipoprotein TraI"
                     /protein_id="HDX4805491.1"
                     /translation="MKALTSLILPVILLTGCSSSPTISPGGVNTPPPDINAWLKPRSE
                     KPDSLSETRWKMLTDAGKTLGFRGGKAQRSWELIQALNARESTLNALYDFRPLISPEG
                     WLPPVIDEAQDVAHITPDQIRTSSRVWTIIRPERFVSNPPGWRDWLLRGLSTTATPGT
                     EGSVVPEDSVQRKVWETALRQGWQEGRQNADLTLEANQKTLTRDYRGMMLYSLLWRQG
                     MITRPDVSDQMQTVTGDGKKLVTGDRVRRLKNHAEFNLQKSHWRPLIGTEGGSR"
     gene            complement(28812..29270)
                     /gene="traH"
                     /locus_tag="ROH59_003041"
     CDS             complement(28812..29270)
                     /gene="traH"
                     /locus_tag="ROH59_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer lipoprotein TraH"
                     /protein_id="HDX4805492.1"
                     /translation="MNRIIPAGCLAALFLAGCNSPSQHTPVPRNYGAASDVAVTRHTQ
                     YTLWDKGVFSGQLPVSTGSHLLTANSDRLSFDWEGDAIELLNELARVRGMQFNYNGVR
                     LPLPVNLHVRDMTFSNTLRLIEAQTAWRATIHQYPGLLQVSFMQPENRKK"
     gene            complement(29665..30249)
                     /locus_tag="ROH59_003042"
     CDS             complement(29665..30249)
                     /locus_tag="ROH59_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDX4805493.1"
                     /translation="MMKPRSSYSKTAFILLFSVFLVAAVTKAKSSLPDITLEQAKEIN
                     ADNTVIFLFRHGERCDRSDMPCYSDKSGITITGTEKAQQEGIKFATIFSEYDIYSSNA
                     VRTIQTAKFFSGKEPVVMDSLSDCNNDLYKTLESIARESHKRNIVIMTHNHCLSFLAR
                     DRLGKKFKPAYLDALIMHYDGTRLILDGKYNKEA"
     gene            complement(30309..31511)
                     /locus_tag="ROH59_003043"
     CDS             complement(30309..31511)
                     /locus_tag="ROH59_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003557916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HDX4805494.1"
                     /translation="MMKKNHITRTIIASAVLFSFNAAAATSYFEARNDAMGGTGVASS
                     HYGVAPLANPALLTKHNSNDDFSLLLPSVGAQVADPDDVSNKADDVKDDWDLFDSAVD
                     NQHGVQQAAANLKHRLQEFRNINADAQVGVSAVAAMANDTLPFALMVKSYGTVSVNGK
                     VNDADLDYLDKVANGTITDVDKNALTSRAFGRAAVITDVGISFAKELETAGQKWSLGV
                     TPKYQRVDLFNYNVTVRDYDKDDFDGDKYHNTKNGFNADIGAYTDLNDNWTVGLVAQN
                     IIPRSIDTKVVNGFKETFKVRPQATAGVSWHNDLFTTALDIDLTPASGFTSDSKRQFA
                     SVGAEFNAWKWAQLRAGYRQNMASNSGSAFTAGVGISPFDVVHIDVSGLVGTDHDYGA
                     MAQLQFTF"
     gene            complement(31597..32421)
                     /locus_tag="ROH59_003044"
     CDS             complement(31597..32421)
                     /locus_tag="ROH59_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001238934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDX4805495.1"
                     /translation="MRLNTTGIAARMMLSLDKKAIGEKLINGRQINPTPLQVRYPQGV
                     REVLGIMSEQLAISTADLTRILLEDALHNMFMPADNTTGNIISRIEYIMLSHDINAPL
                     LATLLSPWNIRSTVIQDPARLADYLSADALEHLAECFNLNPDWLNGHENYPIALSGEW
                     PDTADNFRMFINDSSNTEVIFWHSFPFAGNTKREYCGVILRQKKEINGSVIYPALSLS
                     PTLLNDEKRKWLTEYTTRQNTTMSLRRITLRPGLAGNLITGQILPVSLFNTSLLPW"
     gene            complement(32572..33726)
                     /locus_tag="ROH59_003045"
     CDS             complement(32572..33726)
                     /locus_tag="ROH59_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDX4805496.1"
                     /translation="MPSPRIRKMSLSRALDKYLKTVSVHKKGHQQEFYRSNVIKRYPI
                     ALRNMDEITTVDIATYRDVRLAEINPRTGKAITGNTVRLELALLSSLFNIARVEWGTC
                     RTNPVELVRKPKVSSGRDRRLTSSEERRLSRYFREKNLMLYVIFHLALETAMRQGEIL
                     ALRWEHIDLRHGVAHLPETKNGHSRDVPLSRRARNFLQMMPVNLHGNVFDYTASGFKN
                     AWRIATQRLRIEDLHFHDLRHEAISRFFELGSLNVMEIAAISGHRSMNMLKRYTHLRA
                     WQLVSKLDARRRQTQKVAAWFVPYPAHITTIDEENGQKAHRIEIGDFDNLHVTATTKE
                     EAVHRASEVLLRTLAIAAQKGERVPSPGALPVNDPDYIMICPLNPGSTPL"
BASE COUNT         7960 a         7992 c         8380 g         9443 t
ORIGIN      
        1 tgaacaacat tacagtagcc tgataattta gatatgtgta catcctaccg gaaaagatac
       61 ttctcaggtc atttatcaat gggcgttatt accaccggta gtttgtttac gtcttctaaa
      121 ttaactggta ccggaggtaa ccatattaat ctaggtttac gctcatgggc tagttctggt
      181 ttcttacttc ctgtccagta tgtatgccag tgtccccggc gtatatgagg acgtttgcta
      241 cctattgttg tccgctcttt ccctgtgggt tctgcttggc gatattgccg tatggcttgc
      301 cccattcgaa taccaacgtc ccactcccga atgttttgtg ctggtagttc atggtgagtg
      361 tgaacatgct ttttgtgctt ttctgaccgt ttaaattgat ttttttcttt tatatcattg
      421 atctgtgaac agatataaag caccattgat atctgtgcgt taagaagatt aaactccctg
      481 tctctgaaat ctttgagctt ttcgttaact gttacgacga cttcaccatc gatacactcc
      541 atctttctgg agtcaagaag tccttcacga gagtccttta ttctgatgat attattgacg
      601 acgtcaacat tcttttcttt tagccctgta gttccttgac tttgtttcag atcatcaata
      661 atgaaaagcc ggataatatt tccattattg tccaaaaatg gataaaagaa aaatccatgt
      721 atcggatagg acgtaggaag tatagtatgc agattttcgg ctgaaacata gatactccat
      781 gaagggagtt ccttgaggat ctgtgcagga atgttatctc gactttctgg tttcagaaag
      841 cccttcatca tagagaactc cgatgagtgc caaatgcggg aactacgccg ctaattatgc
      901 ttaattcttg cttttagcag gcggtgaata aaaaggttga aattcatttt cttccgggca
      961 aaaatgccat ttcacacatt agctttgcag gacgacctgc aaacgcttct ttcaccgggg
     1021 acggccccat tgttctggag cctgatatgt cctggatcgt tttattaatt gcaggtttgc
     1081 tcgaagttgt ctgggcgatt ggcctgaaat acacccacgg ttttacgcgt cttacgccaa
     1141 gcattatcac tattgcggcg atgatcgtca gtatcgccat gctctcttgg gcaatgcgca
     1201 cgttgcctgt aggaaccgct tatgcggtct ggaccggtat tggcgctgtt ggggcggcca
     1261 ttacagggat tttgctgctg ggtgagtctg ccagcccggc acgtttgctg agccttgggc
     1321 tgatcgttgc tggcattatt ggtctgaagc tgagcactca ctaagcgcca ggctgtttca
     1381 cccaaatcag tttattcact tcaaaccctt cccgggtcgc gatggctaac atttgctgtt
     1441 tcatttcatc tgaaatagta ggggtccgtg aaaggatcca caggtagtcg cgatccggac
     1501 cacaaaccag cgcgtgacga tattcccggt cgagtgcaat tacgttatac ccgccataga
     1561 aggggccgaa aaaagaaacc ttaagcgcgg ctctgcttgg gtcgccggtg aaataggctt
     1621 tcccttccgt tttctgccac atctccctgt cagggttata gcccttgtta ataacgttga
     1681 tgccgccgtc gtcgcgcaag ctgtatgttg cggtcacttt atccaatccg cgctcgaaac
     1741 gatggtcgaa gcgcgcaatt tcataccagg ttcccagata gcgtttggca tcaaagttat
     1801 ttaccacggt aacgcctttc ggcggtgtcg gggagctaca cgcgacaacc aggaatgcag
     1861 ccgtaactgc agcaacgacg ggcaaaatgc gcatgggatt ttccttgctg tatttttgtt
     1921 aagtgtagat gacaacagga aaaaaagaga aagaaaggag gcccaatatc ctgggcctca
     1981 tcgtcagtta ttgcagcttt tcaagaatgc gccaggccgc ctcgacacgg acagggttag
     2041 gatagctttt gtttgccagc atcacgatgc caaggttttt ttctggaacg aaggctacgt
     2101 agctgccaaa tccaccagtg gagcccgttt tatgcaccca tgaggctttc actgcggggg
     2161 cgggcgggtt tacctcaacg gcgggaagcg ctgccaatgc cactttgctg tcgctgccgt
     2221 tgatgatcga atcagctttc agcggccagt tcagcatctc ccagcctaat ccctggtaca
     2281 tatcgccaat acgccagtag cgagactgcg caagcgcaat gccctgctgg agcgttttct
     2341 cctgaacgtg gctggcatcc atgttggcct gaacccagcg ggccatatca ataacgctgg
     2401 atttcacgcc ataggcttcg gcgtcaagtt gtcccggaga aacgtgtacg ggcttccctt
     2461 cgcgatagcc ccaggcataa tctttttgtt cgttctgcgg aaccgtaatc caggtatgcg
     2521 ccagttttaa tggttgcagg acgcgtctgg tcattgcctc ttcgtaactc attcctgagg
     2581 gtttcaccgc cagcgcgcca aacagaccaa tgctggagtt agcgtaaagt cgcttagcgc
     2641 ccggagtcca ttgcggctgc cagttttgat aaaaatgcag taatgcggct ttatccctaa
     2701 cgtcatcggg gatctgcagc ggtaggccgc ctgccgtata ggtggctaag tgcagcaggc
     2761 ggataccctg ccactgtttg cctgtcagtt ctggccagta tttcgtgacc ggatcgctga
     2821 gcttaatttc gccgcgggcg atagcatcgc cgcccaacac gccgttaaac gtcttactaa
     2881 ccgatcctag ctcaaacagc gtttgctgcg tgactgggtg gttattggcg atatcggctt
     2941 taccccaggt gaaataatag ggttttccct ggtagataac ggcaacggcc atacccggaa
     3001 tagcctgctc ctgcatcaac ggggtgatgg tgcgattaac gatatcggca atctgttgtt
     3061 ctgtttttgc ggcagcaaat gtggagaaag aggctgtcag cagcagagcg cagcataacg
     3121 attttttcat catgaaatca gttccgtaat taaaagcaaa aaggtgtccg ggcccgtcag
     3181 acgcaatcag tgtgtttgat ttgcaccgtg ttgacaaacg gttaaattta gcagcagata
     3241 taagtttttc ctaaattcca cgtgtgtttt ttattagctt caaaaatcac tatttcacga
     3301 agaatttaga ctgcttctca cacattgtaa cattatttac aaccaccttt caatcatttt
     3361 tgataaatca ttgatttcat ctttgctgca atgatactta ataaactctg caagttatcc
     3421 acagagcaac actcaatttt attgatgata ttcttattat accagacatt tttcatacac
     3481 tcccttgtac ggatagtttt ccgacaactt catgattaca tatcttgcgg ttttgattat
     3541 ttttgctgca agaaatacat acttcaaacg aaaggtcttt atttgctgtc tgtattctga
     3601 agagtccaag gaatcaaact tgaacaacaa aaataggtta tatgaaagca tcatcatttg
     3661 aaacacggct tcattcgccc aaaatgactt tagcaagaga tgacccaccg ccatgtcgta
     3721 tttggcttct ttgatatagt tttcagcatt accacgcttt tcatagtata taactacttt
     3781 ttcagaaagc aaggtagtat ttgttacaaa gaaaaagtag tcgtattcgg aaccttctaa
     3841 aagtgataat tgtgctcttt ctttttctgg tttcagtacg cgagatacga caaatcttct
     3901 gtctttttcc catttaacta attttgtata cagttctgta gtttctctac cttcttctcc
     3961 tttaacgaat acaattgatg aattcgttgc ttgtgaggtg agtgtagaat aacttttggc
     4021 tttaattaaa tatttgcatc caagagattc tatcgtttcg ataatttttt catcaaagta
     4081 gccactatcc attcgaaata aaatttctaa atcgtctgat ttgatgttag caacaatttc
     4141 tttgatcatt tccgcagcac cgtttgcagt gtaagtattg ccacttctta caaatccggt
     4201 aacatatgct tttaattcgt cgcaaaatgc aaattggata ttgtagcatc ggtttcccag
     4261 tttcttagga ttatatcctt ttgacgcacc ttcttgatga ccttctacgt taattacact
     4321 actatcaata tcaatcgtaa tggatgtcaa tttactttta gtgagcagtt ttttaaagac
     4381 tttaaaatta atgtctctaa acatttgggt tgtcttgaag ttgaagtttc ctagaaaccg
     4441 tgacactgtt tcaggttctt ttacggaaat atcaaactcg ttgacgaggg gatcattttg
     4501 aagtagcttt agacgttcta acttatcaat gccaatgaag tgaccgcaga gcatggtctt
     4561 tatatgattc atcttgattt tatttgttga gtcattatca aatacgaggt cattttcaat
     4621 aaaatcaaaa atcccattgc tttttgcatt ctcaaggagc agaaaaagac ctgcatttga
     4681 tgttagattc ttagctttga aatcaatttt attaatcata attagaaccc ctttttacta
     4741 cttttcttac tattatttta ccatatatcg agtcataaaa gctgataatt taacatattt
     4801 ttgagcactt ttctttcacc caatgggtga aagctgaatt tcgaaggaat gcatatttat
     4861 caaggctttg attatgcttt ttgaagtact gacgtagaat ctaggttatc aacataggtg
     4921 ttagccacat cactgatgat gtcctcgctt aggcgataaa ttttctttgt atagcgccag
     4981 tatataaaac acaaaatact gtgtggtgac gataattcgt ttccatgaaa taaagattct
     5041 agtttagaag ccagttcttc atttttttgt tggctctgga gacgactcat tagtatgcgt
     5101 tcttcatctt ttctgtcgat aaataataat ggattgtcgc tgcgtttttt atttcggcat
     5161 gcaaagattt gctcttcaag cccagggatt gtgttgatga ctttttttat ctttttcagg
     5221 aaaataggtt gttttaactg cgacatttcc atctcctaag gggattcttt tattaactaa
     5281 aatcagcata acatgcgttg ttgtgaagta gagaaccatg tattgggttg gttgttaact
     5341 tcaaaaacaa cgctgaatca ttcaaataat aaaaggattg ttacagatac gaaagtcgtt
     5401 agaatagctg cgggcgcttg aggctgtatg ccgaaagcgt tttgtggacg gtatacagca
     5461 gaaagcccct ggagattttt ttatcaatca accaagggct ctactgtaat gcctcaacaa
     5521 cattatagta gcccgataac cgccggaagg caatggaggg gctatgatgc cacagcgaac
     5581 gtttttaatg atgttaatcg tcgtctgtgt gacgattctg tgttttgtct ggatggtgag
     5641 ggattcgctt tgcggactcc ggctccagca gggaaacaca gtgcttgtgg caacgttagc
     5701 ctacgaagtt aaacgttaac gggcaacacg gcggcaggtt ttctgccgcc gctttgttgc
     5761 gaaggctgac ctcattgcgc cctttcttct tcaatgaagc gtatctggta ttgtttcatt
     5821 ttccctgaag ccgattagct ccagccgaat gcctttgcca tcgggggcca cgttctgcat
     5881 ttcgcagata ccacgtcggg tcatgagtgt gaaggctgtc attgccagca tggctaacgc
     5941 gttttcctcg cttccgctgc gtttctcgag agcatcggca atttcttcta tgctccccac
     6001 ctgaaagcaa gagtcgaatt ctttactcca cttttctgac atcggatttt ctctctgtat
     6061 ttatgggtag ttatcgaact gaatgtgcca gttttttcag gagacggcaa agttgagatg
     6121 attggttctg attcaaagca tgagtttccc cggtgtgacg ggcatgtcgg gcggattttg
     6181 agaaacaaca gatgtaaaaa aaccgactgg tgaggtcggt ttttttactg ttccgttaca
     6241 gagtgggtgg ctctggtcgg aaaagaactg tctataactg acttgtagat agtacgtctg
     6301 gaattatatt tctgcaagta ctggataagt gtatactcgg catgtcagct ctgaggcatg
     6361 ttctgtccga catattgttc agcgggaaga acaggttgca agtcctggcc aaaacatcag
     6421 gtggtgctgg ttttggtgct ctggtcggag aagaactgtc tataactgac actatagaaa
     6481 ccgttgtgac aggcagtgta agagcgaaca acggggttct ttctccagtg atggagaagc
     6541 ggatgattaa tctgttaatc atcgttctca gggcagtagt tgccgttgca aacgcgctga
     6601 ttgctgttct ggaactgatc cgggaactta tcgactgata agcctggaaa cgtaactaag
     6661 ggcagggagt taccgcttcc tgccctttaa caaaaagaga tctcacgtta aaaatttgta
     6721 cccttcttta acttccagtg cctgctcctt tgactcaaac atcagtcttg ttttcccggg
     6781 aacaccccat gaaatgtatt caacatctat ccaccatttt ccatattctt catatggctc
     6841 ggatattact tttttgacaa aggcgtctac cagattcatt gttttttcct ttttgtgttg
     6901 aaaataatta atgccagagc acagcgaaaa taatgaatgc gctggctgtg ataattgcga
     6961 ttttctccca tatgatattt ttctcatggg ggtttctacg gagattattt cttcgcattg
     7021 agataccggt attcatgttt tatcttggat ttttgttttg ttgtctgtct ggcaggctgt
     7081 tctgcgcccg tttgtgacaa ggttagctta tggggttaaa tggtcacgga catcatgcgg
     7141 acggttccct gtcacatgcc atctggtttt ttcattcaaa ttgagagata ttgctaagtt
     7201 gagtcgcttg cgatagtgga ctcctgtttg caagtgagtg ccattgttta tttcatgaag
     7261 aggattgatt atgagcatgc ctcctgcgat agctaatact ttcttgtttg aaatgatgaa
     7321 gagtaaatca aaagacgtta cacttgctgc gatctatgca ttaggtgaag gccggtgtca
     7381 ggcggagaac attactcgtg aattacatag attgagtcaa agtgatgata tggaaataaa
     7441 aattgctgcg attaaagcac ttggtcgaat ttatcggtaa cggcataagt tatctgttgt
     7501 aatgaacaaa agccggctca tttgaaccgg ctgttatgga gggagcttat cttaaaatac
     7561 ttcggctaca ggtatgcctg caatctgctc ccactcctta cgcttttcct gaatcaggcg
     7621 aggaaagtcg acagggtaat catatcctcg acttgccatc gcgtgcatgg tgtttgatgc
     7681 ggtttctgga tgagtacacc atgatggaat aggaaccatt ggcaggttga tgtatttcgt
     7741 atgaatttcc agtgttttgt cgtctgttac agtacgagtg aaattatgaa tgtcaaaacc
     7801 gataacatcc ataatgttgc ctggataaat acggacatac aacattgtgc catttttaag
     7861 gtcaataccg aaataagctc cctgagttaa agataatcct tcatacccct tctctggaga
     7921 gtagaagcct gactctttta ttgtttgtac aacttttctt attttttctc tccttgtttt
     7981 tgcacgtgag tacatccata tgcctggcgc aagtaataag aaccaactac caaaagtgac
     8041 aacataatct tcgaccttat ttccgaaata acgatcagaa catagcattt cggtaaagcc
     8101 taatgcgcag aacagaaaaa aaggtattcc aagaaagaaa taagcttttc ttaatacata
     8161 ataaaatagc caccaggttg gaaatctgtc tgttgtttct tttttagctt tcatataatg
     8221 cctcccctcg tactatctat tattttaatg ccgatgggga ggttgtgcaa tatttatatt
     8281 gatattatcc ttttattccg tccttgtcgt cacttccttt tgtattatct ttaagacgat
     8341 ctgttttcat tccaggagta tgtcggatat tgcgacttcc tccaataaat atttctttaa
     8401 cagaatttgc catgctgcca agcgtgttgg ctccatcacg tccccctagg aagttaataa
     8461 catgatcagg taggtaggcc tgaagggcaa atatggcagc tacagtggtt gtacaaattc
     8521 tggcgtatat cagcaagaaa ccagcaagac tgaaaatacc ggtcagcgaa ttgaactgta
     8581 cgttaaccag ggcagcgcca aataatgcat tcagtattgt gcctacggcg atgatggcta
     8641 cagaagcaaa gaaaaaacca aagaccatga tgggcggcct tatcatacta tcaattaagt
     8701 atatataacc gtaggctgcc cgacttcctc tgtcttctga tgtcccgaga tgtgttgcag
     8761 cccacagcgg cccggcggta catcctatta atacgctgac tatccagttc ccgatgcctg
     8821 tcatccagaa aataaacgga atgaatggca ggtaaattga taaggaaaat ccagcacaga
     8881 acatcaggaa caaaagaaaa taaacaggtg gtgcaagtgc ttcaaacagc gcggtaagca
     8941 tcgaagcggc acctgttagt gagttaaaga attttacaag aattgaatct ttgccaccgg
     9001 caacgacaac tctggccgtt gtatatatag tccagattcc ttctgcactt accattgtta
     9061 tatctccgat atttttcatt tttatcagag gattaatttg agcactggtt gtgcctgtgc
     9121 cacttgtttc cgttgcaatc ctgttagtga gactaacaag ggggcccata atttcagaca
     9181 aggcagattt cggatcttgt gcatttgcca tgcgttgttc actggatgat actactgtgc
     9241 ccagcggtgg cgtataggag gaattctgca gttgcgtcct ataggcactc atgaccgcac
     9301 tgaataagtc agtatcacca acttctccca gtgatgacat tgaagttaca gctggagctc
     9361 tgtcagccag ctcggccaga cgctggttag cagtggcaaa ggtctgatac catgcgccaa
     9421 gcgttaccca cccgtaggtt gtgagataag atttaagagc ctcttttctg gattgctctc
     9481 cgttatcagt gggtagcgat ttttgtacag cacgttcata ctcgtcggct gctctctgaa
     9541 tccgtgtctc gatatccggc aatgttccgt tgccagaatt tcttttttcc agaaatgttg
     9601 tcacaaactc actggcagcg ttgtccatgt cgctaatcat attatccatg gctgcacgtt
     9661 gtgctgagat aacaccgctg tattcgtttt tactgaaggg attaaagaat tttccaatcg
     9721 tcgattgatc tgttgttccg tttccttcta ctgacaggct ggctgaacca cagataccgc
     9781 tgccattgga taccgtgaca gtgtaattac cactggcggt tttagctgat tctgtcatca
     9841 gtgaagtcga ggatttggcc gtctgattaa aatcatttag tcctgcgtta accgcatact
     9901 tacacagttc catttcaaaa atgccacgcg ctgctgttcg tgtggatgcc tgaactggct
     9961 gtacagtcat tgaataacca tttgcgatat tatcagcggc aagttgcacc atcacattgg
    10021 cggacccaac ccccattatc gatgcgcccc ataacataat gagctgagcg atactccagc
    10081 catttccggt tggaacgatc atcagaaaac ctgcaacgac actcagtgtg ccgacgatat
    10141 cgcgtccggt gctgaatacc tgtccctgat gccccgaacg cacaacatga cggataccaa
    10201 tgaacataaa ccagacaacg gcaagtacgg cgatgatact gttgaacgcc ccgaacatgc
    10261 ttccgatcag agtgggggcg ctggttgaca gtggattggt gactacatca ccgaatatcg
    10321 tgaccagcgc ctggcgagac agatcgtcag gattggttgc ggcagacaca atatcctgat
    10381 aggtcactga agccattgcc ggcagtgagg atatagcaag gcctgcacag agtgcgcgaa
    10441 gtaaaatttt cacagtaact ccggaataga attgcgtatg ggcaaaggcc acacaggatt
    10501 taattaaggg ggatggcgac atgccagtgg tactggcatc tggacgtgat cagtattgtt
    10561 tactggttac ggcaattaac gtggcattgc gccagccatt gcggtcgttc agaaaatcac
    10621 ggaaagtccc ctgctcgggt tcgctgactt ttcgttcatg caactgccag aggcggtatg
    10681 taacaatcag tgctctggaa gcacaaagag cgacgcctga cagtatcagc acaagagtgc
    10741 tgatggcgcg taccagagtc gtaagaggta atgaagaggc ggcaaagagc ataccactga
    10801 gaaacaaagc gatggccagc agactccagc aacagaatcg ccatactgtt ctgcgccggc
    10861 ggaaacgacg atccaggtcg tctactgaca tatggctggc ctgcagagct tcttcccacg
    10921 agaggcagag ttgcgccttt ttattattta cctgacgaaa tttttccagc ctgctttttt
    10981 gttgcttaag catatgctgt acagaattcg ttatcaggcg agtctccatc agcggaacaa
    11041 aaatgttaat aatcctccgg gtggctatgc gggttatgga tggtgatttt ttgacgtttt
    11101 tcgtctggtc tgaattttcc ggtaacttat tcattttttc agtcctgttc tgacgtcagc
    11161 tttcaacgtg cgtttgcctg attgattgtt ttctcaaggc taccgagttg tttttcataa
    11221 tactggcggg cagtcagagc cagttgctgg ccagagataa cattaccctg gcggatctgt
    11281 tctttcagat cgttcagctg ccagttcatt tgcgcagtga ttcttaccag ttcacggagc
    11341 aggttatccc cctgcatttc ctgtaaatcc accaggtatg ctgtgttggc gtagcgccgg
    11401 ccagcctcaa aagcttcaaa ctcacgggta ctcatatatc cccgtgcttt tgcttctggt
    11461 gaagccacct ggtcgaagta agcggccgct gagtctgact gcagtgtttc agccagtgct
    11521 ttacgtgtgc tttcattagg cgtgctgtca gcaatcagcg tcagttgggg attcgacgca
    11581 gaatcaatga tgccgttgta ttcgttctgg agtccgacgt aggttcgccc actctgggta
    11641 ttcacttctc ctttacccag agcacgaccg gcagaggggc gggaagtgtt tttcatgtaa
    11701 gcagtcgctg catctatttg cttctgatcc catgtcagtg ccgcaggtgt gtccgctgta
    11761 cctgcgccgt ggtaaatcga gcgtacctga ctgtctccac ctggtatttc gcccacagaa
    11821 ggacaaacgg cggttcctcc aaaacgtgca tattctgctt ctgtacagta actggcgtgt
    11881 atggccgcgc catcataagc ttcccgcacg ggagagtttg ctgcgctggc cagacggtcg
    11941 cggatgctac ggttgctcac accgccacct ttactgagtt ttgaggctgc ggatgctgag
    12001 gcacttttgc tttctgttgc aatccctgat gcggattcac tgcagatgga gtctggcacg
    12061 gtgaagcttt tccgtgcctc ctcgaggcgc tgagtttcat tactgaaaat catctgctga
    12121 cgtgtcgcct gtccgttctg ggcaatgaca cttgccagct tttcagagtt ctgattgata
    12181 gcggtacccg tggctgtctg ggtactcagt atgttgccaa ggacatcttt gatggcttcc
    12241 attctgggga tgacctgctc ttcaacaggc cggctggcga cgacggtgac tgaataagca
    12301 tgagcctggc atgccgttcc actcagggtg gctataaggg ctgcgagtaa tgtttttctt
    12361 tgcattttat tgtctcctgc tcgggatgga gcacaaggtc aggaaggctg tcgtattttc
    12421 tgtcttcagg tagtggggcc agtgggaaac actgatatcg cctggtgata taacctttcc
    12481 tgttccggtt atcgatgatg ctgaaagaac gacgtctgac gcgccgtaag gtggaagggt
    12541 cagtatccat aacaggccag tcaccggcac tcagtgccgg cgttccggga acggatggcc
    12601 ataaccaggt atcatcggac atcagcgaag ccagcggtga agggagtatc cactggatga
    12661 catgctgaac gtcgaatggt gcttcatccg ggacagaaac ctgccatatt gccgttgtta
    12721 tcagctcatc tgtgctggac ggcaacaaca gccgcatgcc tgtgaccttt ccctgtgttc
    12781 tggcatccga ggcgtatatc actctgggat tgggggccgg atgtaacctg aagacacgtg
    12841 acggcagagt gaatgagaaa ctgtcacctt ttacctcaag ttttttaaga aatacctgcc
    12901 ctctggcagg tctccggcag cgtggggtga tatgaattgt acacatcaga gattgtatcc
    12961 ctgttttcgg atgagctccg aggccagttc ttcaataaca ttgtcactgt tatgttggcc
    13021 cgcccggtgc tcaattaatg acgttgcaga acctctgggg aagttttcgg ccagaatctt
    13081 acgtgcccga actgaaccta acttatttgt cagtgtttta cgcagggcac tgtcttttgg
    13141 cgatgagttc agcgcccata gctccagtgg accgacggta aatttgagta ttctcgcaag
    13201 cgtgccactt tttaccctga atactcccag aacaggaaca ccactaccat ctggtgccgg
    13261 gccttccggc attttcagga agcgtttcag cataaattca ggaacgttga agttatccct
    13321 cagtacgggg atatcttcgg gtttgtagcg cagtaaccag agagtatttg ctgacttaag
    13381 aacgctttcc gggtagtccc tcagatactg cgtactcaga accgtgcgga tagcaaactt
    13441 gcgttgctca cgctcctggg tatccagatt ttcccagatg aagtcaatgc cccgggcgtt
    13501 atgcagttca tcataaactt ttgtcttaac ctcctgatca agttggttaa tacgtttaag
    13561 agcgatttca tggtattccc gtggaagctg ctttaacact tcatccctgt attgtggcag
    13621 ggtgaagtca ccaccggcga tctgacctgc aagcaggtac atgatgccgg ttttaagcct
    13681 gcctgcaggc gttttgtcac cggcaacatt attcagatcg acagcgataa cccgggtttc
    13741 cgggttgatc ataaaccggg tatacccgga tatcatgggg tagtcgttat gtccctgctc
    13801 cagggcgcgg cggatgtagt ccagcagaag ctcgtttgaa ccatcacgct gaacagtacc
    13861 gaaaacatcc ctgagactgg tatggcccag catagaggat acttcgggaa gctggggcat
    13921 tgcctgataa tgtgcccgct gagccgccat gatatacccg gcattgtgga gcatatcccg
    13981 gacttcgaac caggttgatc tggcccacca ggctgcatca tgtttttcat acagtcccga
    14041 gtcctgcagt gctgaatcca ccaggtcttc cgttgaggcg cgataaagtc gcggattatt
    14101 ttcaccgtac tctttaaaag ccagctcgat aagctggttg ataatttgtc gggtgtctcc
    14161 ggggttacag ggttgaccgg taccggtatc gacacagaga gcacacagca ccgatgacat
    14221 gaaattcttt tccggcgtaa taggcttttt agcgccgtac atcacgtcaa aaaggttacg
    14281 ggtgtattcc ggatcattgc tcagaataat accgacagct tcgtcttttc tttccggagg
    14341 aagactgtcg cgaataagct gaaccagtcc ctgagcactg tatcctttat cgatataggc
    14401 aatgaagggc aggtttttct gagcagatga tatctgtatt tccgacaacg tattaatcag
    14461 aactgattta cccagtcccg gatcgcctgg tgccagttct gtatgtttat tttgttggga
    14521 tgacgccaga ccaacctcaa atgcggaacc gtcttctgta tgtaacatca gattcccttt
    14581 gcctcgccag acagagcctg ccctgttaag tgggaaaagc gagatggcat gtgacaacgg
    14641 gggatacagg ggaaccgggc cggagcctcc ggatgccgcg agaatggtat tcacccaggc
    14701 gcgtcgggga tcaccaaatg ttgtcgtggt gccacatacg ccccagcctt caatggccga
    14761 tttcagaatg gcctggtttc gtgtgcatat ttcacgtgtt tttccccacg tggaggccat
    14821 gatggtcatt atgcagacag gttctttttc atccgttgcc gccagggtca taacggattc
    14881 atacattgga cgaacggcag aaatgaagct gctgtaagtc agaagcgttt tcttcagatt
    14941 aagagccttc atcccgccgg gcatcagatc cattctgatg cgccagggga ctgcgcgggg
    15001 gacggcacgg accagttcgt taaacgtctg cagattttgc ggaggtaaag taatcgatac
    15061 cattccgtgc cagagtccgc ccgcctgaac caggttgccc tgtgtggtca cctgcgtgtt
    15121 gaataactgc aaatgcaatg aaggagcatg tagtacggat tcatcgtcag tccagcgata
    15181 tcccgctggc tgggcatctt caggcaggtg gggttgccag ttacgcggtg tgctgtgccg
    15241 ttctgtctga cgacgtattt cacgcccgac ctcgtgtata tccagtagcc ggagaatcag
    15301 gccatcagat gaatgtctca gtgcctgttc cacattatca agaaaagctt cgtggcggat
    15361 tttcagtgca gataaggtcc actgccaggg ggactgggca aagcgtgctt tcggtacccg
    15421 ttcagccagt cttctgacaa gctcatcatg ggcggtgcga tcgctgttgc tgataaggtc
    15481 gggtccactc cagatcgcca gccagcaacg ctcccggacc agccatgggg acagtgttgt
    15541 gactttctca tcgaccacat cctgtaactg gatacctgta ttagccagtg agcgcttttg
    15601 tggggcgacc atgtcttcga tttcttcttt ccccatgtca ggatcacgct caaaaacgca
    15661 gctgatttta tgaccgctgt ttttatatgc cgtattcagg ctgtcactca tgctggtgat
    15721 cagcgattcc agtgaacctg ggccagtctg gtcggatgct tcatccattt ccctgaaagc
    15781 accgctgact tcaaagacag agagatattc tccacgcttt gtggctgcaa tatagggcga
    15841 attcagccat gggcgacgtt cacgatcctg tctgtccaga ccaattacag tacgtaaatc
    15901 gcaatactca acaaaactgc ttgcgacaga gaaacgggat agcgtgttca gacagtcttc
    15961 gatagtgaag attaaacggt ttatgttcat aggtgaggga actccggact tacaggaggg
    16021 aggtttgtgc agtttgattt ttttaatgcc accccgcgct ggagtggcat gaagaaaaat
    16081 caatcaacgt attctttttt gatgaatgaa tctggtgtca gaatcagggc aatcccgttc
    16141 attttttcac gcaggggcga acgaccggaa ggtggatagc gacgaaaaac gtcagcgaaa
    16201 tcggccgggc ggaaactgcg gaatttatcc tcaaccgcca gtctgttttg catcagtgca
    16261 gagagcgctt cccgtccccg ccggacccgg aacttatcat tactgaaaac ttcctgtaat
    16321 gaacgacggt taagggccac gaccgtggat ggatgaaggt cgggtagcca caccataacg
    16381 ccctgtgctg cggcataacc attcagtgaa tgccaggcgt ggcagaaagc acataagctg
    16441 taaggcgggc cgtcttcatg aaacagttcc tgctctttct ctgacaacga ctctgtactg
    16501 gtgatttcag ctttctgtac atggcggagt gaaagacgtc tggcagacag acgggcctgc
    16561 tcaagcgccc gttcagcggc ttttactgcc gtgttgtact tttccttttc gccggttgcg
    16621 actggttcac cacgcttttt taacttatcc agatgttctg tggccttatt aagacgaact
    16681 cgtgtgtcac tgattgtgtc ggtaagctgt ctgagtggcc atgagtcatc cagtctgaaa
    16741 cggtgcctga cgttttgccg gcagcagata catcgaccgg gcgttgttaa ttccggttcc
    16801 ggtaacagtg gctcctgtgt atgaaccaca tcaatttctg gaaagggata caaccacaag
    16861 tctttaatgc tgtgttgcat gagcaggctc cgtactggtg taacgtttca cggcttccag
    16921 aatgatgttt gcgatttcat cggaacagca ttctgcaaaa atgaattcct gatcgtcccg
    16981 actgtcgtgg gcaatcacat tgccgttttc tgttcgtcgt aacgttatgt gctccgggct
    17041 ccaggcagac atatgtgcct ccttgtattg ccgaacagga agggcaccgg ataaatgcca
    17101 gtgccctgga caagattagc caatggaaat tgaggaaatc cccaactgtt tctggctgcg
    17161 actcatcatt tcaggtccgg cgacaagtac cgccccaatg acgatagata caatgcaacc
    17221 agccagtccc atcccccctt gtttcccaac ttttttcagg ccaatcaggc ccccgagaaa
    17281 cagaattacg ccgatgaact gcgcaatagt gattgatgat gactgtgctg ttttagcacc
    17341 ttcaccaaca ttgcgaacca tatcggcaag atctccatcg gcaagaacgg ctttgggcag
    17401 caacatcatg ggaatgagca gcaggtactt agtcagtttg ctccggcatg acattacaaa
    17461 cagttgtgca tggataaatg cggcgtacag acgggccgcc acgacacgaa tacgtgacat
    17521 agtttctcct taaatggata tatcagtggt ttatatgaag gtgaaaaaaa tcagaagacg
    17581 attccaatgc ttgccagcag ggcattgagg acacgatcga taaagaccag caggacgccg
    17641 gcaataaatt tgacgtttcc tttactgacg gattcactgg cactcagtgc ggtatgtcca
    17701 tcgagtccgg ccttgcgcca gatggatatc ccgttcatga caaatcccac accggccagc
    17761 ttggccagcg acagaactgc atttgctgcg ccagcagcag cgccaaacgt ctgaggttgt
    17821 acatatgcaa tcggaccaaa tgagtcagcc ctgaatccca tttgtacacc tccggcgtta
    17881 atcattgccg ggagtgatac gagcatgcag ctggttaaca tccccgcaat aaattttccg
    17941 ggagacattt ttaccggacc ggctgaacgg gcgcgggcaa acagggtaat catgctgatc
    18001 accccgatga attctcccca ggtaaacagg aaatccattc cggcactgaa aatactgctg
    18061 gcaaagttct caatggcggt cagggcatcc atgttcatca gcgtaacgtc cctgcactgg
    18121 tgatgatggt ccgggtcgtc ggatcaatcc gctggatcac cacattgccc agagtctgac
    18181 cttctctgac agcccaggta ctaccctgcc agcgaatcca ggccatgcca gtttccatcg
    18241 acatgatttt cattccgtta agtacagacg acgttttttt ctttgctgga tgcggtgtgg
    18301 aagaggattc agtgacgctt ttctgtgtca ttattccgtt caggcggctc cggatatcat
    18361 ccagctgacg gcgcgtttcc tgtgcgtatt cttcatcctt ttttatagct tcgcccagct
    18421 tgttaatgct gtcgtgaagc atattcagtg ttgcctgaat tttttcatcc cggttatcca
    18481 gctctgtttt tacatcccgg gcaagctggc tcatatcttc tcctgtccgg acagtcatag
    18541 tctcagtgga ctgaacggaa ggtgatgatt cttgggtggt ttgccaggtc tgtacgccag
    18601 catccgcatc attaaacgaa ggcatgcctg tttccgatgg cgctctcagg aacagatacc
    18661 atatggcagc gagcaacacg actgcacata gcccccatgt tgctacagat atcccccaga
    18721 cggaacgttt ccagaagggg gcgggtttct cttcgggttc accgaagctg ccggtttcat
    18781 ctatttctgt ttcaggtttc attatggtgt ctccggttgt tcatcatacc gacgttgcat
    18841 cacagctttt ctttgctcca tggctgtctg cattcgtgcc tgcgagcgtt gttccgcctg
    18901 tgatgtacga ttaactgaag gggaaatgcc actggaaagg gaagaggacc tggcgtcgtt
    18961 tgtcattacc gggtcaacaa acagaattga tacgacttca tgctgataca cttctacctg
    19021 tttatagggc tcactttctg cctggcgggt taatatctgg cttcctcttt ccgccatacc
    19081 accggcaata acgcccgcaa cagcttcacc actgggcatt cccacgcgtc cggtaaccgt
    19141 gccatagtta ccctgaataa cctgcgtgtt ggcatcttta taaagtgtgc caatactgcc
    19201 cacacctcct aacactgacg gcagaatgat atgtttaaac cagcgtgtat tcacattgct
    19261 ggccacggat gacatcaggt tgtcttcccg ttgtgcatat gcattgacct taaggtccat
    19321 gccgttccag ctcatccggt cgaaatggat ctccacgccg ttacccacca gtttgactcc
    19381 cggactgaac agcgttgccc ctgcccaggg gccagccgga atggttgcga taaccttgga
    19441 tgacgggtta tcagaatcca ctgcagtatc aatatatgcc ggtatacggg tcagagcagg
    19501 tatcagttgt atcccttttt ctgctaccgg cgtggacagg ctggcattct gtaatgcgaa
    19561 ttgctgcgta ccattctgcc ctgttgtttc tgccggagat ttattccaca tagtcgttgc
    19621 tatggttggt gtactaccgg caggatgctg atcttttatt cttacaatca gcttttgcag
    19681 ccgctccata cgcttttcac tggctgctcg atcctcctgt ggtgtgccgg aagcctggcg
    19741 atgagcatag ttttccggtt ttgttgcagg ctgttgttgc ttttccggag tgtccggaat
    19801 atcaagcccc tgtggaagac tggcaatgaa cgtctgatta ttgcgggctg cagctgcggc
    19861 ccctcgttca ttatccgctc ttaacagttc acgataatga ggcgtttcgg taacgctgcg
    19921 cgttccgccg cttgctgcac tgttaatgtt cacggctgac tgcatatcgc tgttactccc
    19981 tgatagtttg gaaaacgcga tatagccgcc gccaaataag atgatgctgc ccagtccaag
    20041 cagggcagcc agtttctttc cggatttacc ggcatcctgt tcagcactca tgattactcc
    20101 agttctggtg tcacgtgaac ggactggcca ttcacagaga aagtcagtag tggggtgacg
    20161 ggaagcttcc agagatgagt tccgtcggcg gaggacaagg tctgttcaaa ttcatcgcgc
    20221 aacatcgccc gggaacgaac cagaaggtca tcgccgtgtt gccagatcgt tgtatccggg
    20281 acattacctg tgaatttcag cctcttaact gaagggtccc ggggaggaat accatcaaga
    20341 aatgcctgta atgttgcatc atgcagggcg attttatccg tcgggatgga gacaaccggg
    20401 ctggttggtc cctgccgtgg tattcgcaga tccagacgac tgtccatttc ctgactggat
    20461 gacggcgtat ctgtttcgcc actggttacg ttcaggatga ccggtaccga cagacctttc
    20521 aggtagacag aaatgtttcc ggatgcccat ggccgcaatg gtgtgattgt caccatgttc
    20581 ccgttgtact gcacatcaaa gagttttggt gccgcgttat aaggaggatc ggattgtggc
    20641 catggtgaac cgttgatatc ggtaaatgtc accacgctca ggttgttcat ggctgtgcga
    20701 acaagaggaa ggctggcacc gggggacaga ttaactgtca gagagctgat acggggtaca
    20761 acactggtga tgggcgcatt gatggcccgc tcgttatccg ccatgagact gcgtagtgag
    20821 cgaatttcat cggcggagag ctcagaatca agtcttgccg catcctgtac cagcgggctg
    20881 gcctgcccgg gggcaggcag ctcacctttt accagtgttg ccggaacacc tccggtgttt
    20941 tgggaggcat tctgaacgtg atcgctggca gaatttgtcg tttgtggtgt gcgtgcgttc
    21001 tgccatcctg cgttatcggc agacgtggcg gcgctgcaca ccaggagcag tgtgctcagt
    21061 aaataacgtg attgcatatt acttatctca ggagttcggt ccggcgttac gggagatcat
    21121 ctgccggatt tccataccgg atggtttcag tctggggtca acacgctgga tggtgatttc
    21181 gaaaacaaaa gactgttctg gcttgctggt tgtctggccg accagacgca tacggacagg
    21241 atactggaat gtccagaacc atacgccgtc ggacatttgt ccctgtcgta ccagaacgcc
    21301 agcacctgtc gtggcggtca gattcatctt ctctttcttg atcgtctcca gaatgttaga
    21361 tgcctgtaat gcattcacat atccgacaaa accttcgtca gaaaaacgcg gagacaggga
    21421 ggagatctgt gaacgatagt gcacaaaatc caggttgaat gcggtcgcca gtgcctggct
    21481 gccaaaggcc attgcatcat tctgactcca tgctggctga cttgttggtg ccagcctgac
    21541 cagacgacca ttgtctgtag cgaaatattc gcgctccaca ttcgttgagt gccagtactg
    21601 aatggcgtta ccagtaatac tgataagaag acatgtgccc gtacataaaa gcgcttttat
    21661 cagcgcaggg acattatttg cccgctgttc tgactgcttc atagccctga ttgtgctctt
    21721 cagtatttcc gggtcaggtg ccggatgtga tggcgaggat ggctcggtat tttcggtcat
    21781 aggttgtagt ccttccaggg atcaatattc cccggcagct tttcattcac cttgtccacg
    21841 accgcgtcgc agacctggtt ttccagctgc gacagaatgt cgtcaaggct ggggaactgg
    21901 gggaggttta tgctgatttt tttgattcgt gacagacagg actgcaggga tgaggaaaca
    21961 tcgttttcac gttgtgacca tgcatccgca gctgcacgtg ctcgctcata tcctgtatta
    22021 ctaccggcct gtgccgcgct acccgcacga caggttgcag cacttgccgt ggatgaaatc
    22081 aggataaggc cgagcacggc aaccagagac ttatgcatgt tcatatggct tccttaccgg
    22141 ctcatcggcc ggggctgtgg gagagatcct gatgcagagt tttttcctgc ctgtcctccg
    22201 gcttttggct gttggaccac tgctgccatg actgctcgaa gcccaggttc cggtacaacg
    22261 catcaggttg tttttccggc gtgtagacag cagcaaaaag cggttcttcc cgggttttca
    22321 gatgaaactg cataagctcc ggtgcggggc gattcgtgct gtcagcatcg tggtttaccg
    22381 cttcaccata acctgcaaag cgtaaacctt tgtcggtcag cgcattgata accagctgac
    22441 tgttgtcggc tgatggggtg gccagtgccg gatacaatgt gccgttcagc cggaccacac
    22501 cctgcagatg ttcatcggca ctctggacaa gtagcaggtt gagttcacgc gtatccttat
    22561 ccactgatcc cagaacaggt gtcagcttgt caggggctgc gctggttatt tctgttacct
    22621 gatttgcgtt ctgtggcgcg gagaccggat gtcggtcttc accgataaac agatgtgagc
    22681 cgacgttttc tggcatacgt aacgctttca tctcttcggg ccacccctgg ctgatttgcg
    22741 cagccacttt cataaaggtt tcgaccggaa tcgcctgaat acgctgacct ttatccggat
    22801 tatcatgtga taccgagatc ccgttggtaa ctgactccat ggaccactta ttccggaaac
    22861 gtgctttttg ctctcccggg aggatgaatt gttcgcggtt ctgaagtgtc agtgtcacca
    22921 cgtcaccttt ctgatggttt ttgaccagac tttccagttg ttccccccag tagagtttgc
    22981 tgccactgcg gtttttaagc tcaacaaaga aactttctcc tttgccgggt gcatattcag
    23041 cacgaccaaa attgtgcagt acggcagtca cgctctctcc cgggcgaagt tttcctggtg
    23101 gttcttcacc tggtgctgca tctgccgttt tgcctggttc agccggtgat gatgcaggag
    23161 cggtgctgac ggttgatgct tcaggggcag caggggacgc cggggattgt gtggcttctt
    23221 tttcctgaac ggggtcaggg acagccggtt gttcagggat attccggtta agttccggtg
    23281 ttggctgatg ggtgacaaca gcatccttac tgacagccat ttccttgcgt aatttttcta
    23341 gttcagcccg ttgatctggc aatttcatcc ggacatcgat gttgtgctcg ataatcaact
    23401 gcattgcttt ttgcttaaag gcatcactgc ccgtcagctc tatgacgccc ccataaaatt
    23461 tggtggccac agcaagtgcg gccagaacgc tgcgatcgtc attgctggca ccgttgacca
    23521 tttccagccg gtttacccgg tcaatgaagg ctggtttgcc atccagtttg tacaggacgg
    23581 ttctgtctgc tcgtttttcc cagtcaagct ctttaagaat ttcgtccatg ttgagcgata
    23641 tcggtgcatc agaacgttcc ggggcgtaga caatactgtc aggtatcggt ggagtcgtcg
    23701 ttgtttctgc tgagggcgtg ggatcactgt tctcatgcgc ctgtgaatcc gtttttttac
    23761 gtgtaaaaaa gccacgcgct ttgtcgagaa acgatgaagt attatcagaa ggtgatgtgc
    23821 tctgaacagg ttgctgcgga gtgggttcat cccggacagc cggttctata gtggctgttg
    23881 tggcctgaag ttctgactca tctgcctgaa cgtggcctgt gtccggttgc gacggcatat
    23941 cactgttttc ctgcagatgc tcaggatttt cattgttcat cagctcctga tatgcgctgt
    24001 agtcttcgta ttcttcgggg ccatctgact caggaaggaa cggctctggc tgaaggggaa
    24061 tgtcttcagt tacatggttg accgcctctt cccggggagt atccggggat attccgatgc
    24121 tttgtttgtc atcaggctcc gtcatcactg tcatttcctc tttgactgca tcaggggaag
    24181 gtgatggctc ggctgattca ttcatggttt cagatgaggg actgtcttca ggggatgcgg
    24241 gggcggcagc aggggccggt atttcaggtg aagtgccgga ttcctgttgt gactcgtttt
    24301 tttccggttg tgacagttcg gcttcaaatt cacgccagtc tttatctgtg gccaccgaga
    24361 caactttttc cggaggttcc gctggatgag cgggttcatc aggggcagac gccgttgtac
    24421 tttccgggga cgccggtgat tctgcagggg agtcctgaac tacagagctt tccgtttgcg
    24481 cctgaacgtt atcagcgtgc cgctcatctt tgccgttatt ttcagtggcg tgactggtaa
    24541 atgactgtgt ttcatcagca atgttactgc tggaagcagc tggttgttcc tgctgcgtgg
    24601 cggacggcag agaaggtccc tggtcatggc tgtgccctgt atcgggtgat gtttcaggat
    24661 attctgtcgg agtcatggtt ttttcctcag tgtggaccgg tgtaaaaacg aggttgccga
    24721 tcaccagtgc ctcccggatt tccggggtgt tactgttggg ggtggaaacc ccgatatgtt
    24781 ctaactgggc gttgatgaca tgcagaaaag ctgcccgtcc ccggctggca tccaggtcat
    24841 tgaaatcggt cagcccctgc gctttttcgg catcggtgaa cgcaggaaag atgaccgatc
    24901 ctcctgtcag ttctgcggct tttgttgcac tgacgatacc tttgttaacc tggcgtgcat
    24961 gatcgttgtc ggcacagaag ataaaggggc tttgcttcca tttttgccgg gcctcttcgg
    25021 ccacaataat catgttgccc gcatccactg tcatcagtac cggaaggcct gtggcttcgt
    25081 gcagggaggc ggcagtggcg tagccctcgg caaacagtac cggctggccg ttgcgcggcg
    25141 tgcccagcgc aaaccagtta ccggttttct cggaatcttt caggatgcgg gcatccttcc
    25201 cgccggtgac cggaatgcgc tggtaggagc gtattgcgcc gttacggttg ctgaaaggaa
    25261 taacaagctc atttttgtcg tttattcgca cccccggcgc agcctgaatg cctttccggg
    25321 tcaggtattc atgtgccgtg gcctgcggcc atttgctgac atagcggcgg gcataggcag
    25381 cctgtcggtt gtactgtgct ttcagttccc gctccgcgtc ttccctgcgt tgcatcgaat
    25441 gcgctttcag gtgaagtctt gcgcggggat ctgtctgctc tccgccggag aaagtccagg
    25501 tgaccggcga atcgtctgcg ctgcggtaat ccctgtacca gccggcaggt ctgccgtcca
    25561 ggaagccgcg atatgcgcca cttttttgtc cttttttgtc accggcggtc gggacacggt
    25621 ggattttccc gtccatgacc ggcagttctt tcagaaccag cccggcattt tccagtacct
    25681 gggcaaactc ggtgaccggg tcactgccgt tcatggagac ttcctgcggc cggggcagcc
    25741 agcggtccag catggacagg tccgcccccg ggcgggcaaa ccagagtttg tgctctttat
    25801 cccagagaac gggcgtgtgc ccgttcatcg ggggatgtgc ttttttgaga tcttcgattt
    25861 catctgcagg cacggcaagc caggtgcggt atcgggatac agacggcatg agtgcttctc
    25921 ctgaaaaaag acggaaaaaa accaccgccg gaaaccgggg gtggctgggg gaatagaaaa
    25981 ccgggggaga aatgtttgtc agggtctcca gtctgtaccc ttattccagc gatcctgcca
    26041 gtgttcaaga tattgtgcgg ctacatccgg catattctta agcacaacga cattctctga
    26101 attcttgcgt gcagcagcac gagagaagtt ataggagcca gtttcaaccg tgtttccgtc
    26161 aacaatgatg actttgtcgt gatggatggg gaaggcatct acagtccgga gaggaatgtc
    26221 cagcaggttg atatatttca tcgcttcctg acttgcccgg ttcgtattcc ccttgtcatc
    26281 aacaacaata cggacgtcca ctccgcgttt tttcgctttt gccagcgcat gcattacatc
    26341 cgggtcggtg aaggaatatg ccatcatcct gatggagctt tccgcactgt tgattgtgtc
    26401 aagcaccaga gcggatgcgc ttccttcagg agaaaagccg accttcacgg atggcgtgtc
    26461 gatcattgca aacgatggtg tcgtgaacag taacgggcat gccagtagcg atacccggag
    26521 cagagtaacg atagtttttt tacctgacat aaagactcca gaatttaatc gaggccagtc
    26581 cagtctcgtg gtgattccgt atggtggcga taccaccatg gacgaccgga ggcgatggcc
    26641 cctctcagaa tgctgaaaat gcgagtacag atcgtcctga cagtccagcc tgaacggtcg
    26701 agaataacga aaaataaaat gatgccggtg caaatccaga aggttgtttt ggagggaaag
    26761 gggcatataa acagataaat catggtgaac ggcagaggta cgccctggat gttgactggc
    26821 ggtgttgcat atcgccagaa accttctctt ttcatgaccg taactcccct ggcgggataa
    26881 aaagaatcgc ttctcttcgg tcaacttcat tccggatata catttccaga atctggtccc
    26941 ggatacggcg cttctcctgc cggattatgg catcaatgtg atgcccccac tctgcatgcg
    27001 gcattccgga aagattgtcg cgaagctcat cgttaatgac gatatattcc cggacggctt
    27061 tacgaccacc gtcatttgtt ctgaccagaa cctgaaccag aatgaactgc aacagtgaca
    27121 ggacagccca ggccatcgaa tccctgatga cagggggaaa cagcccaaga agacgtgcca
    27181 gcgtttcacc aggagatttc gtatgcatgg tgctcaggca gtaatgcccg gtgttgcctg
    27241 cctgtaccgc tgcgtcggcg gtttcgttat ccctgatctc accaacaccg ataatttcgg
    27301 gattacgtcg tacagcagaa cgcagtccgg cagcaaaact gaccacatca cgcccgattt
    27361 ctgcctgatg cggtgggagc agatcgtttt catttcccag gatatattcc accgggtctt
    27421 catatgtcac gattttggcg tcggggaaat tgtccataat gtaacggtac agtgctgaac
    27481 acagcgttga tttccctgac ccggtttcac cacatacaaa tcccagaccg cttttgcaga
    27541 ccattgcttc aagcaggtct ggttcaatgt tcatggagag gatgtccggt atttctgtcg
    27601 ggatgacacg catggttatt gatattgctt tctcctccgc accagatgtg ccctgaatga
    27661 ggtgagagcg taaccggatg cgttctccgc gtttaagacc atagcgaccg gatgcatccc
    27721 cgttaatctg tatcgtcctg tcaaccggat tgcctgccag aacgcgggga atgacttccc
    27781 gaccgaacag ttcatcaatc agggaggaca tgagtgtggt tggtaacgtt gcactggaac
    27841 aacgcacccg tcggccaaag cgactgacag atacaggtga cccgccggtc agatccacat
    27901 cactgacttt atgtgcggcg caccagacaa agaaatgccg tagttcatct gccgtgaaac
    27961 gctgaaacgg aaaaagacca aactcatcag gaatattcat cgggagcctc cttcagtgcc
    28021 tataagcgga cgccagtgag atttctgaag attgaattcc gcatgatttt taaggcgacg
    28081 aacacgatct ccagtgacca gttttttccc gtcacctgta acggtttgca tttgatcaga
    28141 aacatccgga cgggtgatca tgccctgacg ccagagaagt gagtacagca tcatgccccg
    28201 gtaatcacgg gtgagggttt tctggttggc ttcaagcgtc aggtcggcgt tttgtcttcc
    28261 ttcctgccat ccctgccgta atgcggtttc ccacactttt cgttgcacgc tgtcttctgg
    28321 aacgacgctg ccttctgtac ccggagtggc tgttgttgaa agcccccgga gaagccagtc
    28381 acgccagccc ggtggattgc tgacaaagcg ttcagggcga atgatggtcc agacccggga
    28441 agaggtccgg atttgatctg gcgtgatatg agctacgtcc tgtgcttcat caataaccgg
    28501 tggtagccag ccttccgggc taatcagtgg ccggaaatcg tataaggcat taagtgtgct
    28561 ttcccgggcg ttgagtgcct gaatcagctc ccatgaacgc tgagccttgc caccacgaaa
    28621 tccaagcgtt ttacctgcgt cggtcagcat tttccagcgt gtttctgaca gactatccgg
    28681 cttttcactt cgtggtttaa gccatgcatt aatgtcaggt ggtggcgtat tgacaccacc
    28741 tggcgagatg gtaggggaag aagaacaacc agtaagcagt attactggca aaatgagaga
    28801 ggtgagtgct ttcatttttt ccggttctcc ggctgcatga agctgacctg taacaggccc
    28861 ggatattgat ggattgttgc tctccaggct gtctgggctt caataagtct caacgtattg
    28921 gaaaacgtca tatcccggac gtgaaggttg actggtaacg gcaggcggac accattgtag
    28981 ttaaactgca tccccctgac tctggccagt tcgttcagta attcaattgc atcaccttcc
    29041 cagtcaaagg aaaggcgatc gctgttagct gtcagaagat gagaccccgt tgaaaccgga
    29101 agttggccgg aaaacacacc tttgtcccat aatgtgtact gagtgtgccg ggtaaccgcc
    29161 acatcagagg cagcaccgta gttacgcgga acaggagtat gctgagaagg ggagttgcag
    29221 ccagccagaa aaagggcggc aagacacccc gcaggtataa tacggttcat aataattcct
    29281 gagcagttaa atcagaatgg gatataccgg tgctccggta cagacaggat gatgtttgtt
    29341 tccggctata cttgcgttac cggaaataaa tgccagtgtg gccaggtaaa tagcctcata
    29401 gtttactgaa ggtgattatt cctgatactg gctggttgat gtgtcgtcag acataaaacg
    29461 aatatgagcg taatctttaa cgctccgcgc cgaatcgatc catgatggat gactcgacga
    29521 tttatgaatc gaacgtaccg gcgcttgtcc ctgaaacagt tcccggccct cgtccggata
    29581 acctgcaatt cagacaggca catgtgcccg tacactcttg tatcttactg agtatatcag
    29641 aatttatgta aattcaaata tcctctatgc ctctttgttg tattttccgt caagtatgag
    29701 ccgggtacca tcgtaatgca tgatcagggc atcaaggtac gccggtttga atttcttgcc
    29761 gagcctatct ctggccagaa atgataaaca atgattatgt gtcattatta ctatgttcct
    29821 tttatgagat tctcttgcga ttgattcaag cgtcttataa agatcattat tgcagtctga
    29881 taaactgtcc ataacgacgg gttctttacc ggagaagaat tttgcagttt gtatggttct
    29941 taccgcattg ctggagtaaa tatcatattc actgaagatt gttgcgaact taataccttc
    30001 ctgctgtgct ttctctgtac cggtaatagt gattccgctt ttatccgaat agcatggcat
    30061 atctgaacgg tcgcaacgtt ctccatggcg gaaaaggaaa ataacggtgt tatcagcatt
    30121 aatttctttt gcctgttcca gggtgatatc gggaagcgag ctttttgctt ttgtcactgc
    30181 cgctaccagg aaaacagaaa ataaaagaat gaatgctgtt tttgaataag aagaacgtgg
    30241 tttcatcatg ttatttaaac tgaatataaa aatacccccg ggtttagtgc cgggggcggg
    30301 gacagtaatc agaaagtgaa ctgaagttgt gccattgcac cgtaatcgtg gtcagttcct
    30361 accaggccgg aaacatcgat atgtacgacg tcaaatggag agataccaac gccagcggtg
    30421 aaggcgcttc cggagtttga tgccatgttc tgacgataac cggcacgcaa ttgcgcccat
    30481 ttccatgcgt taaattcagc accaacactt gcaaactgac gtttgctgtc agaagtgaag
    30541 ccactggcag gagtcagatc aatgtcaaga gcagtggtaa acaggtcatt atgccaggat
    30601 acaccggcgg ttgcctgcgg acgaactttg aaggtttctt taaagccatt gacgacttta
    30661 gtatcaatac tgcgtggaat gatgttctgg gcaacaagac cgacagtcca gttgtcattc
    30721 aggtctgtat aagcaccaat atcggcgttg aatccgtttt tcgtgttgtg gtacttgtca
    30781 ccgtcaaaat cgtctttgtc gtaatcacga accgttacgt tgtagttaaa caggtccaca
    30841 cgctgatatt ttggtgtgac gccaagagac catttttgtc cggccgtttc cagttctttg
    30901 gcaaatgaaa ttccgacgtc ggtaattaca gctgcacgcc cgaatgcgcg tgaggtcagg
    30961 gcattcttat cgacgtcggt aattgttcca ttggcaactt tgtccagata atccaggtct
    31021 gcatcgttta cttttccgtt tacgctgaca gttccgtaag acttgaccat aagggcaaac
    31081 ggcagagtgt catttgccat ggctgctaca gctgatacac ctacctgagc atctgcattg
    31141 atattgcgga attcctgcag acgatgttta agatttgctg ctgcctgttg tacgccatgc
    31201 tggttatcta cagcactgtc aaacaaatcc cagtcatctt taacatcatc agctttattt
    31261 gatacatcat caggatcagc aacttgtgcc ccaacagacg gcagaagaag gctgaaatca
    31321 tcattgctgt tgtgctttgt cagtaaagcc gggtttgcca gaggtgccac accataatgg
    31381 gaagatgcta ccccggtgcc acccattgca tcgttacgtg cttcaaaata tgacgtcgct
    31441 gctgcagcgt taaaggaaaa taatacagca gatgcaatga tggtgcgggt aatatgattt
    31501 ttcttcatca tttaatttcc tgtttatcag aatttagaca aaacaacgct atgacacgga
    31561 tgtgccgtaa atttttactt tggtactatc tggtatttac cagggtaata aagacgtatt
    31621 aaataagcta acaggtagta tttgccctgt aataaggttc ccggcaaggc caggtctcaa
    31681 cgtaatgcgt cgcaaagaca ttgttgtatt ctgcctggtt gtatattcag ttaaccattt
    31741 tcttttttca tcgttcagaa gtgttggtga taatgatagt gccggatata ttacagagcc
    31801 atttatttct tttttctgtc tcaatattac cccgcaatat tctcttttcg tgtttcctgc
    31861 gaaggggaaa ctatgccaga aaataacttc agtgttgctg ctatcattaa taaacattct
    31921 gaaattatca gcagtatctg gccattcacc ggacaacgct atcggatagt tttcatggcc
    31981 attcagccag tccggattga gattaaaaca ttcagcaaga tgttcgagag cgtcagctga
    32041 aagatagtct gcaagtctgg ccgggtcctg tataaccgtg gagcggatat tccatggcga
    32101 cagcaatgtt gccagtaatg gcgcatttat atcatgcgac agcatgatgt attcaattct
    32161 gcttattatg tttcctgtgg tgttatccgc aggcataaac atattatgaa gagcatcctc
    32221 aagcaggatt cgggttaaat cagcggtgga tatggctaat tgttcgctca ttatccccag
    32281 aacttctctt accccttggg ggtaacggac ctgcagtggt gtcgggttta tctgacgacc
    32341 gttgatgagt ttttcgccga ttgctttttt gtccagcgag agcatcattc gggccgcaat
    32401 accggtcgta ttcagtctca ttgttcctcc gactgaaaaa gtcttttcag ctcatgtggt
    32461 tattgtatct tcggtgtttt ttctggtgaa acgaataatt tcgatcatgc agatcgaatg
    32521 tgtttggcga gttgttgcaa ctcgcctttc tgtatgtgtt ttgaatgatg tttacagcgg
    32581 ggtgctgccc gggttcagag ggcaaatcat aatgtagtca gggtcgttaa caggtaacgc
    32641 tccgggagat gggacacgtt cgcctttctg tgctgcaatg gccagtgtac gcaacaaaac
    32701 ctcactggcg cggtgaactg cttcctcttt cgttgtggca gtgacgtgaa ggttatcaaa
    32761 atcaccgatc tcaatacgat gcgctttctg cccattttct tcatcgatgg tcgtgatatg
    32821 ggcaggatac ggcacaaacc atgctgccac tttttgtgtc tgccgccggc gggcatcaag
    32881 cttactgacc agttgccatg cacgaagatg agtataccgt ttcagcatat tcatagaacg
    32941 atgtcctgat attgcagcaa tctccattac attcaggcta cccagttcga agaagcggct
    33001 tattgcttca tgccgtagat cgtgaaaatg caggtcctcg atgcgaagtc gttgtgtggc
    33061 tattctccag gcatttttaa agccggatgc ggtgtaatca aaaacattgc cgtggagatt
    33121 aacgggcatc atctgaagaa agttacgggc acgtctggac agaggaacat cccgtgagtg
    33181 accgtttttg gtttcaggta aatgagccac accgtggcgc aaatcaatgt gctcccaacg
    33241 taaggccagt atttcgccct gccgcatggc tgtttcaagg gcaagatgga aaatgacata
    33301 caacatcaga tttttttcgc ggaaatagcg agaaaggcga cgttcttctg aagacgttag
    33361 ccggcgatct cgtccggagg atactttcgg cttgcgaacc agttcaaccg ggttagtacg
    33421 acaggttccc cattcaacac gagcaatatt gaacagagat gacagaaggg cgagttcaag
    33481 acgtacagta ttacctgtaa tggctttacc cgttcggggg ttgatttctg ctaaacgaac
    33541 gtctctgtat gtagcaatat caacggttgt tatttcgtcc atattccgaa gggcaatggg
    33601 atatcgcttg ataacattgc tccggtaaaa ctcctgttga tgccctttct tgtgaacaga
    33661 aactgttttc aggtacttat ccagtgcgcg tgacagggac attttacgga tgcgtggaga
    33721 aggcatgcta acctcaaaag aggcaaaaaa taatgccaac aatcattctc tgcaa
//
LOCUS       DAPOXO010000055        33463 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPOXO010000055 DAPOXO010000000
VERSION     DAPOXO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33463
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.055"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..99)
                     /gene="safA"
                     /locus_tag="ROH59_003046"
     CDS             complement(<1..99)
                     /gene="safA"
                     /locus_tag="ROH59_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HDX4805497.1"
                     /translation="MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTL"
     gene            complement(347..2626)
                     /gene="ydeP"
                     /locus_tag="ROH59_003047"
     CDS             complement(347..2626)
                     /gene="ydeP"
                     /locus_tag="ROH59_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HDX4805498.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDDVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPHAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKSGAQAVTVEDSMSMVHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
     gene            complement(2965..3879)
                     /locus_tag="ROH59_003048"
     CDS             complement(2965..3879)
                     /locus_tag="ROH59_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4805499.1"
                     /translation="MGKTFSIKVLFGIYLLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVILPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKSGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNSVVMPTGGCTVDSRNVTVNLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSARQVFANTAPDATKASGVGVSLMRNGKTLATGENVSLGTVNKSKVPLG
                     LSATYGQTGNKVAAGAVQSVIGVTFIYE"
     gene            complement(3939..4442)
                     /locus_tag="ROH59_003049"
     CDS             complement(3939..4442)
                     /locus_tag="ROH59_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX4805500.1"
                     /translation="MKRLHKRFLLATFCTLFTATLQAADVTITVNGRVVAKPCTIQTK
                     EANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPIETSAVTAIVTGSTDNTGYYKNEG
                     TAENIQIELRDDQDATLKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALI
                     NVIYIWQ"
     gene            complement(4455..4985)
                     /locus_tag="ROH59_003050"
     CDS             complement(4455..4985)
                     /locus_tag="ROH59_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX4805501.1"
                     /translation="MKYNNVIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDGNMRPVKLNDLHTGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVSASATFTLEFQ"
     gene            complement(4999..7650)
                     /locus_tag="ROH59_003051"
     CDS             complement(4999..7650)
                     /locus_tag="ROH59_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX4805502.1"
                     /translation="MTAFRAAFKAYRMHQVLILPRFARLTFALGLATAVFPVDAEYYF
                     NPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLNDEFMASRDITFIADDNNADLIP
                     CLSTDLLVSLGIKKSALLDNKEHSADKHVPDNSACTPLQDRLADASSEFDVGQQHLSL
                     SVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQS
                     GINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHINTSAERDIIPLRSRLTVGDSYTDGD
                     IFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTAQVSVKQNGYDVYQTTVPPGP
                     FTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGN
                     NLQSSPKFVQASLMHGLKGNWTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQAN
                     TTLADDTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFYNLSDSAYSRMSGYTVK
                     PPTGDTSEQTLFIDYFNLFYSKRGQEQISISQQLGHYGTTFFSASRQSYWNTSRSDQQ
                     ISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNA
                     SYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTQGGNTSSGTSGYSSLNYRGAY
                     GNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQT
                     GIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQ
                     IGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGNDK
                     NSNCIVDYKLPAVSPGTLLNQQTAICR"
     gene            complement(7692..8402)
                     /locus_tag="ROH59_003052"
     CDS             complement(7692..8402)
                     /locus_tag="ROH59_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDX4805503.1"
                     /translation="MQTTRTPYSVSFMATVLLLFLFACHSTIANAAVALGATRVIYPA
                     NQKQVLLPVTNNDPASVYLIQSWIENAGDQKDTQFVITPPLFSMQGKKENTLRIINAT
                     NHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTHLAMAPEEAPA
                     MLRFRRSGSILTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAVTGDISF
                     QTINDYGALTPLIKATMQ"
     gene            complement(9508..10830)
                     /gene="hipA"
                     /locus_tag="ROH59_003053"
     CDS             complement(9508..10830)
                     /gene="hipA"
                     /locus_tag="ROH59_003053"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system serine/threonine
                     protein kinase toxin HipA"
                     /protein_id="HDX4805504.1"
                     /translation="MPKLVTWMNNQRVGELTKLANGAHTFKYAAEWLASRYARPLSLS
                     LPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVT
                     LIPEDETVTCPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTAL
                     LRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVP
                     DAEIIKAGRVRALAVERFDRRWNTERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIA
                     QIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDII
                     SAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLKFPEVQMHEIL
                     SDFARMIPAALDNVKTSLPTDFPENVVTAVETNVLRLHDRLSREYGIK"
     gene            complement(10830..11096)
                     /gene="hipB"
                     /locus_tag="ROH59_003054"
     CDS             complement(10830..11096)
                     /gene="hipB"
                     /locus_tag="ROH59_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HipB"
                     /protein_id="HDX4805505.1"
                     /translation="MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISN
                     FENNPDNTSLTTFFKILQSLELSMTLCDAKNASPEATEQQDLEW"
     gene            11404..12162
                     /gene="tam"
                     /locus_tag="ROH59_003055"
     CDS             11404..12162
                     /gene="tam"
                     /locus_tag="ROH59_003055"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HDX4805506.1"
                     /translation="MSDWNPSLYLHFAAERSRPAVELLARVPLENIEYIADLGCGPGN
                     ITALLHQRWPAARITGIDSSPAMIAEARSALPDCLFVEADIRNWQPEQALDLIFANAS
                     LQWLPDHYELFPHLVSLLNSHGVLAIQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQHFL
                     TRYHQMLEEQYPLQENGQILLAFPRLFIVARRTE"
     gene            complement(12166..13080)
                     /locus_tag="ROH59_003056"
     CDS             complement(12166..13080)
                     /locus_tag="ROH59_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HDX4805507.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIVFAHCLRMTLRKQPQAEVLAHYLKTEDLQRVLASNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(13277..14728)
                     /gene="uxaB"
                     /locus_tag="ROH59_003057"
     CDS             complement(13277..14728)
                     /gene="uxaB"
                     /locus_tag="ROH59_003057"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDX4805508.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFA
                     LAALIAFYRGVRNGETYPVQDDAHWLERYQQLWSQYRDRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            complement(14955..16373)
                     /locus_tag="ROH59_003058"
     CDS             complement(14955..16373)
                     /locus_tag="ROH59_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDX4805509.1"
                     /translation="MHVQPISTFRLFQEGHLLRNSIAIFVLTTLFYFIGAELRLVHEL
                     SLFWPLNGVMAGVFARYVWLNRLHYYAISYVAMLVYDAITTEWGLVSLAINFSNMMFI
                     VTVALLVARDKRLGKNKYEPVSALRLFNYCLLAALLCAIVGAIGSVSIDTLDFWPLLA
                     DWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAF
                     PLPALIWCAVRYTPQVTCLLTFVTGAVEVVLVANSVIDISVGSPFSIPQMFSARLGIA
                     TMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEALKSPSLKQTQHLTV
                     MLLDIDYFKSINDNYGHECGDKVLSVFAQHIQKIVGDKGLVARMGGEEFAVAVPSVNP
                     VDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGCASYRTLTDDFNKLMVEADTC
                     LYRSKKDGRNRTSTMRYGEEVV"
     gene            complement(16512..16871)
                     /locus_tag="ROH59_003059"
     CDS             complement(16512..16871)
                     /locus_tag="ROH59_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HDX4805510.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGVKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGEALSEEQQR
                     YIVTVIYHWLVIQMNQP"
     gene            complement(16871..17797)
                     /gene="glsB"
                     /locus_tag="ROH59_003060"
     CDS             complement(16871..17797)
                     /gene="glsB"
                     /locus_tag="ROH59_003060"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HDX4805511.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            complement(17861..19249)
                     /gene="sad"
                     /locus_tag="ROH59_003061"
     CDS             complement(17861..19249)
                     /gene="sad"
                     /locus_tag="ROH59_003061"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HDX4805512.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGVDDIENALQLAAAGFRD
                     WRETNIDYRAEKLRDIGKALRARSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLVAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEDNALGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITIAKDAEHALELANDSEFG
                     LSATIFTTDETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRV"
     gene            19350..20231
                     /locus_tag="ROH59_003062"
     CDS             19350..20231
                     /locus_tag="ROH59_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4805513.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNRRYPKIQFSLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGHAPVTRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVVAGAGIALIPRSMLESMPGHHQVESWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDAPDSAKQGYQ"
     gene            20309..20392
                     /gene="yneK"
                     /locus_tag="ROH59_003063"
                     /pseudo
     CDS             20309..20392
                     /gene="yneK"
                     /locus_tag="ROH59_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
     gene            20570..21760
                     /gene="ydeA"
                     /locus_tag="ROH59_003064"
     CDS             20570..21760
                     /gene="ydeA"
                     /locus_tag="ROH59_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HDX4805514.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAHSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIGALLTLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(21785..22450)
                     /gene="marC"
                     /locus_tag="ROH59_003065"
     CDS             complement(21785..22450)
                     /gene="marC"
                     /locus_tag="ROH59_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HDX4805515.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EVKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            22662..23096
                     /gene="marR"
                     /locus_tag="ROH59_003066"
     CDS             22662..23096
                     /gene="marR"
                     /locus_tag="ROH59_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310164.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HDX4805516.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     SGAAICEQCHQLVGQDLHQELTKNLTADEVATLEHLLKKVLP"
     gene            23117..23500
                     /gene="marA"
                     /locus_tag="ROH59_003067"
     CDS             23117..23500
                     /gene="marA"
                     /locus_tag="ROH59_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HDX4805517.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNN"
     gene            23532..23750
                     /gene="marB"
                     /locus_tag="ROH59_003068"
     CDS             23532..23750
                     /gene="marB"
                     /locus_tag="ROH59_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HDX4805518.1"
                     /translation="MKPLLSAIATALILFSAQGVAEQTTQPVVTSCGNVVVVPPSQEQ
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(23781..24680)
                     /gene="eamA"
                     /locus_tag="ROH59_003069"
     CDS             complement(23781..24680)
                     /gene="eamA"
                     /locus_tag="ROH59_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416050.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HDX4805519.1"
                     /translation="MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVA
                     FPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIV
                     LGAFTFGERLHGKQLTGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNI
                     FNKKIMSHATRPAVMSLVIWSALIPIIPFFAASLILDGSATMIHSLVTIDMTTILSLM
                     YLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFFGAV
                     LIMTGLYINVFGLRWRKAVKVGS"
     gene            24875..26062
                     /gene="ydeE"
                     /locus_tag="ROH59_003070"
     CDS             24875..26062
                     /gene="ydeE"
                     /locus_tag="ROH59_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HDX4805520.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTFCFVIGLVGFIFSGNSLLMWGMSAAVFTVGEIIYAPGEYMLIDHIAPPGMKAS
                     YFSAQSLGWLGAAINPLVSGIVLTSLPPFSLFIILALVIVVAWVLMLKGIRARPWGQP
                     ALC"
     gene            26189..26284
                     /gene="mgtS"
                     /locus_tag="ROH59_003071"
     CDS             26189..26284
                     /gene="mgtS"
                     /locus_tag="ROH59_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HDX4805521.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            complement(26503..27393)
                     /gene="dgcZ"
                     /locus_tag="ROH59_003072"
     CDS             complement(26503..27393)
                     /gene="dgcZ"
                     /locus_tag="ROH59_003072"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HDX4805522.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTAALTDYKIYLLTVRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKATN
                     DEEACRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEG
                     KQTGRNRCMFIDEQNVINRV"
     gene            complement(27647..27751)
                     /locus_tag="ROH59_003073"
                     /pseudo
     CDS             complement(27647..27751)
                     /locus_tag="ROH59_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00156 family protein"
     gene            complement(27900..29945)
                     /gene="dcp"
                     /locus_tag="ROH59_003074"
     CDS             complement(27900..29945)
                     /gene="dcp"
                     /locus_tag="ROH59_003074"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707439.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HDX4805523.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQTPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLEQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNNWL
                     IPLLNTTQQPALAELRDRATREKLFTAGWRRAEKNDANDTRAIIQRLVEIRAQQAKLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNETHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGTAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGRRFREAILSRGNSEDLERLYRQWRGKAPQIMPMLQHRGLNV"
     gene            30082..30828
                     /gene="ydfG"
                     /locus_tag="ROH59_003075"
     CDS             30082..30828
                     /gene="ydfG"
                     /locus_tag="ROH59_003075"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HDX4805524.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWSNIDILVNNAGLALGMEPAHKASIEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            30917..31603
                     /gene="ydfH"
                     /locus_tag="ROH59_003076"
     CDS             30917..31603
                     /gene="ydfH"
                     /locus_tag="ROH59_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YdfH"
                     /protein_id="HDX4805525.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            31780..31983
                     /gene="ydfZ"
                     /locus_tag="ROH59_003077"
     CDS             31780..31983
                     /gene="ydfZ"
                     /locus_tag="ROH59_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HDX4805526.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(32019..>33463)
                     /locus_tag="ROH59_003078"
     CDS             complement(32019..>33463)
                     /locus_tag="ROH59_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDX4805527.1"
                     /translation="SAKATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADILATEHFS
                     DWGYYEVNLIGGEQQIADLQQQDNLYTVAEMSADAWTARVVGVVKKALHVQIDGLETV
                     LAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVVADVQNPHQPKTATGVIVEAL
                     ARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAIDVKLAQWIEDNVTFPSTMVDR
                     IVPAVTEDTLAKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGVELVSDVL
                     PYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRHAAYTLMLQEQAPTLKVQG
                     VDLQDYANRLIERYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKFDLLALG
                     VAGWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGTARVQSLLAIKAIFGDDLPD
                     NSLFTTKVTEAYLSLLAHGAKATVAKYSVK"
BASE COUNT         8802 a         8231 c         7654 g         8776 t
ORIGIN      
        1 caacgtaagt gtcagtaaca agacaaccac aattacagac atgatttctt tatagttgtc
       61 tctttgcgtg attttgtttt tcactgtggt cgcatgcatt tcaaatgtgt ttatttagcg
      121 gataacgtta aaaatcgtta atcagtatga ttaatataac aggctggata aaagaggaaa
      181 taggactggc acttcagtac tgagcggagt ttcttacaac tgtaggcaga ggtttatatc
      241 ttatagtgtg tagtttaatt taatccatgt gagcaaattg cgcgataata gtcaatgagg
      301 aattcttctg ctgtgcggat gacagcagaa gaaatgagga ggagaattaa tttgatggtt
      361 ctaattcaac cggaatactt ttatagccag gaatgccact taatggatcg tggttatcaa
      421 gtgttagcat gtgattcgat tctgggaaat aggtcaccag tgagcggtca gccatagggt
      481 aaatgaccac ttttaatcta tccatgcggc gtgagctacg tttaccgtct ggcgtgagtg
      541 caataagatt aactctttcg ccgtttttta cacggcaaat tttagcttgt ttagcactca
      601 taaagaccac atctcgttga ccgaatacac ctcgatagcg atcatccata ccataaatcg
      661 tcgtgttgta ctgatcgtgg ctgcgtactg tcgccatgac cagcttactg ttaaacgctg
      721 aagaaggatc ttctaacagc cctttgctgg taatgaaatt agccttacct gacggcgtca
      781 tccagcgcct ttcagcagct gcgtttatca ggtgaaaacc accaggatga cggatgcgct
      841 ggttatagtc ggcaaactct ggcagcacag cttcaatgtc attgcgaatg cgatcataat
      901 cttccaccag atactcccag gctaccacgc tctggggtag tgctgcctgc gcgattcccg
      961 cgaccactgc acactctgat ttcagcatta caccggcggg ttttaacaca ccacgcgagg
     1021 catgaaccat cgacattgaa tcctcaacgg ttaccgcctg cgcaccgctt ttttgcatgt
     1081 caatctcgct acgtcccaga accggcagaa tatagctatg ccgtgcggtc agcagatgag
     1141 agcggttaag cttagtggct acgtgtaccg ccagatctaa ttgcgttaac ggtacagcgc
     1201 tcgcttcccg atctggcatt gccagtgcaa agttgccccc catgcagatc aatgctcgag
     1261 cttgccccgt acatatagct tgcatgctgg ctattgcagc atgtccaggt gcatgaggtg
     1321 gggtgaagcc atagcgctca cccaggcgag ccagaaactc tgcagacggt ttctcggtga
     1381 taccgacggt tcggtcgccc tgtacattag agtgacctcg tagtgggcag atacccgcac
     1441 caggcttgcc aatgttacct ttcatcaaca gcagattgac cagttgctgt acgttctggg
     1501 taccatgttc gtgctgagtg atccccattc cgtaacagat aatggttcgt tcggcagcgg
     1561 catatgcatc agcaagttcg gcgatttgtg tctgacttag tccagaaata cgttcgatat
     1621 ctttccactc ggaattgagc acgtcacggc gtagctcgtc aaagccgacg gtatgcgttt
     1681 gaataaattc gtcatccagc aatgagggcc gacctgcggc gcttgcagca tcatcgcgct
     1741 caattaacag gcgcatcatc cccttgagca acgccatatc gccaccaatg cgcacgttat
     1801 agtaggcact ggctaactga gtctcagagt tcgtcagcat ttcaaacggg ttttgcggtg
     1861 cggtaaatcg ctccaggcca cgttcctgta gagggttgat agcgatcatt ttcgctcccc
     1921 gtttcactaa agcgcgcaac gaagtcagca tgcgagggtg gtttgtacca gggttatgcc
     1981 caatgcaaat gactaaatcg catttctcaa agtcttccag caacacggtc cctttaccca
     2041 caccgatact cgctgccaat cccacactgg tcggttcatg gcacatgttg gagcagtcgg
     2101 gaaagttatt gctcccgtat tcacgggcaa aaagctgata aagaaaggca gcttcattgg
     2161 aagtgcgccc cgaagtatag aattcaacct gattgggatc actatagctt tgaaggcgag
     2221 cgccaatttc gtcgaaagct tgttgccagc ttaatggctt gtaacagtcg ctgacgtcat
     2281 catatttcaa aggctgagtg agacgtcccg cagcctcaag ctcgtgatct ccccaggtaa
     2341 gtaatgattg aaccgtattc tcagcaaaga aagaggcatt tacctgctta tccgtgactt
     2401 cccaggcgat tgcttttgcg ccgttttcac aaatgtcgaa tgacgcactg tgcttaggat
     2461 ctggccatgc acatcccgga cagtcaaagc cctctggctt attcatgtca aacatggcaa
     2521 taacatcctg gcgtatatcc atctgcttac gtactgcatt cgctacggat ttaacagcac
     2581 cccaaccacc ggcagctccc tggtaggatt caattttttt cttcatctgc ttatcctgtg
     2641 tggaaatgaa ctattaggat ttgtaatagc gatgatgcac aatatataca tagggtttat
     2701 cgtcaacatg gatatataag agtaggggac tactctctta ctatttttac tctattatcg
     2761 ttaaataata gagtagtata aatacgataa gttaagcatc atctctcata gggtttaaat
     2821 taacataatt ctcaatataa aaaataagac tctggcttca attgtgcgcg gattttctta
     2881 caagtgtagg ataatagcct tcacaaaata attatccgcg caattttcgt gaatggagcg
     2941 catagactaa tgtcaaaatc acaattattc atagataaaa gtgacaccaa tgactgactg
     3001 gacggctccg gctgcaacct tatttcctgt ttgtccatag gttgcgctta aacccagagg
     3061 tactttgctt ttatttactg tccccaggga gacattttct cctgttgcca gtgtttttcc
     3121 attacgcatc agagagacac ccacgcccga tgcttttgtt gcatctggtg ctgtgttagc
     3181 aaacacttgt cgggcactgt cagtggtggc acccgaaaga taaaatgaga gcttttgttc
     3241 gctagagcaa tatacaccaa ggggtatttc tgcgcttcca ggaaagtccg ggagattcac
     3301 ggtgacatta cgactatcaa cggtgcaacc gcctgttggc ataacaacac tgttatttga
     3361 aataatattc cacgtaaaat tacgtggatt tccgcttcct aacgtggcaa ttttatacat
     3421 atgaatacgg gcaataactt cccctgattt tatgacaact ccaccggctg ctccgactgg
     3481 ggtaatatag agttttaacg gtaatggcat cggtgtctta tcaccaatat ccaatacgtt
     3541 ggtatttgtc gtcaacggga aggggtaggt cacattattc cagtacagtg atcctttata
     3601 tgactgtagg gagcctgcga aagctgatcc ttgtaccagg tttatatgat cagtgtcgta
     3661 ccagccgccg taatcattcc agcaacttat atgctgagac aagtctacaa ccagattctg
     3721 gcccggtagt attacaggat cgagattaac ataaacagag gttgtacctg ctccaatact
     3781 tgacccgcca tcgacattac aactaaaggc aaaaactttg cctgccatta atagaagata
     3841 aataccgaac aggaccttta tactgaatgt tttacccatg atatatccta aggttaaaaa
     3901 attgatttaa aaaggaggca aataaaatca aattgatgtt attgccagat atagatcaca
     3961 ttgattagcg cctcgatcgt tccctggctt gcgtttccat tcaccgtgat agctcttgcc
     4021 ttaagtggaa actgtgcatt acgagtgatc tcatcaacaa taaccgtttt gctatcgcca
     4081 ttttttaacg tcgcatcctg gtcatccctt agctctatct gaatattttc ggcagtacct
     4141 tcatttttgt aataacccgt attgtcagtt gaacctgtca cgattgccgt cactgcactt
     4201 gtttcaatcg gacaatcggt taatgacaaa gtaatattgt gccagccaga tgcagaacca
     4261 ggttgttgca gattgcgtgt ataaagatcc ccgagattaa cgttagcttc tttggtttga
     4321 atagtgcatg gtttagcgac tacccgacca ttaacagtga tagtgacatc ggcggcctgg
     4381 agagttgctg taaataacgt gcaaaacgta gctaacagga acctcttgtg aagtcttttc
     4441 atatctgact ctgattattg aaattcaagg gtaaaggttg ccgaagcgct caccagtcct
     4501 ggattgacgg acttctgagt tgacttcaaa cgagcggagt aaggcaaaat attgttctgt
     4561 tctggtacca atgggatcca ctgcatcccg gtatgaaggt cattcaattt caccggacgc
     4621 atatttccgt ccagtatttc tatacccaaa ccggaggccg tattgcttcc ttcatccagt
     4681 ttcaacagag tattattttc tgcatcctca ataccgttaa atgcaacccg cacccccgtt
     4741 gtccctttgc tgcattcact taacgtaatc tgaaaaggga cggcaggact tgtgctaccg
     4801 gtcgttggaa attgtctggc actgtttttt tggagatcta cggtaaaatt aagcgaatcc
     4861 gatgagactg tgcagccata atcgagaacg cgcccgctaa ttttaataac gctatctgcg
     4921 gataaagcag aataggtggt taaccccaga cataaaccga ggaaaataac gttattgtat
     4981 ttcataatct attgttcctt agcgacagat tgctgtctgc tggttcagca aggttccagg
     5041 agagactgca ggaagcttgt aatcgacaat acagtttgag tttttatcat tgccccatga
     5101 aacctgtaat ttccctgact gtggaagtcc agtcagataa acctgaccat tttccgcgac
     5161 aatgctgcca tttttattct ctccgtgagt gacaattgca ccgaatggaa cgcttttatt
     5221 accgtacttc aacgtcatta atactttccc gccgatttgt gcattaaatg ttgctctggc
     5281 aatagcaccg tgagttggga tgacagtgac tacggtttca tccagttcaa cattatctgc
     5341 aagggaattc gcgttaagag cgacacgatt ttctctatat tctgtcgcaa atggtaatat
     5401 ggcatagcca cgccagtcgg tatgaattcc ggtctggttc tctattttga cattatcagc
     5461 gccaggagcc ttaaccagaa ccattgtgtc gcccagcggc tgtccaaagg tgatgccatc
     5521 agcatgagca ataatcccac cactcattcc gtaataaatc tggctgctgt caccactccg
     5581 actgtaaccg acattcgtat taccgtaagc tccacgataa ttaagagaac tgtaaccact
     5641 ggtgccagac gatgtattac ccccttgggt gttaccgacc tgaacgctat aattcaggtt
     5701 attatccggc agcagagtgc cataaacccc tgataggttg gtcatgccgc ctttcaaatc
     5761 gtttgacata ctgtaactgg cgtttgaatt acgaaatgcc gactgactgt ctgtacgcat
     5821 ccaatgacta aagggaacat taagtgtaaa agcgagtaaa tgatcccgat cgttttgcca
     5881 tatattattg gaatagctgt aattcagcga agtcgtaata tcaccaaacg gcacatttaa
     5941 tccaaatgat atttgctggt cgctgcgtga cgtgttccag taactttggc gactggcact
     6001 gaaaaatgtc gtaccgtaat gtccaagctg ctgagagatg cttatttgtt cctgaccacg
     6061 cttactgtag aacagattaa aataatcaat aaatagtgtc tgctcactgg tgtctccggt
     6121 aggaggcttg acggtgtaac cactcattcg actgtatgca ctgtcggata agttataaaa
     6181 accttgcgta gaatagcgat atcctgcgac ctggatattg gttcccgtct ggtagaagga
     6241 tttgctgtag acggatttaa ccgattgtcc gctgtgacgg gtgtcatctg caagcgtcgt
     6301 attggcctgc gtgatatcga aagaaaaggc accaaaaagt cctaaatctt taccaatacc
     6361 aaggttgaag gcctgataat cttctgcaat ttgcattccg ccataaggtg tccagtttcc
     6421 tttcagacca tgcatcaagc ttgcttgtac gaacttgggg gagctttgca ggttattccc
     6481 actacgatat tcccccatgg caagtgcata acgcgtatat ccagcacgtt ggagaaccgg
     6541 aacagacgaa taaggaacat ataatgtctg aatactgccg tctgcctctt ttatggttac
     6601 ttgcagatca ccaccattgg ccgcagagtt gatatcatca atagtaaaag ggccgggtgg
     6661 gacagtagtc tgataaacat cgtatccatt ctgttttaca ctcacttgtg cggtgccacg
     6721 agcaatacca tgaatcaccg gagcgaaacc atgttggcta tcgggcaaca tcgcttctgt
     6781 tgaatttatt ttaaggccac gaaagttcac actgtcaaaa atatcgccat cggtataact
     6841 atcacccact gttaaccgtg agcgtaacgg aataatgtca cgttcagccg acgtattgat
     6901 atgctgccat ttattgctgt cagatgaatt gctactccca ctgttataac tccacgttga
     6961 gttatcgcgc agtcgccaac taccaatgtt gatgccactc tgtaaattca aatatgcata
     7021 gttggatttt cctgcattat ggttactacg gttattaata gaattaccat taaaactata
     7081 gtttagtagc ccggcattta ttccttcttc ccacagatca ggagaaacat agccgcgagc
     7141 cattctgccg acatatattt gcggaacgga gagtgacaga tgttgctgac caacatcaaa
     7201 ctcagatgat gcgtcagcca aacgatcctg aagtggtgtg catgcgctgt tgtccggcac
     7261 atgtttatct gccgaatgtt ccttgttgtc taataatgct gattttttta tgccaagact
     7321 gacaagaagg tctgtactca ggcatgggat gagatctgcg ttattatcat ctgcaataaa
     7381 agtaatatcc cgactagcca taaattcgtc gttcaaataa atgtcgaccc gatatgtacc
     7441 aggtggggcc tcgcgtccct tagtaaaggc agataaatcg acagattcag caaggtcatt
     7501 gcttaaaaac cgtggattaa aataatactc tgcgtcaacg ggaaaaaccg cagttgctaa
     7561 gccaagggca aaggtaagcc gtgcaaagcg aggcagtatt aacacctgat gcatacgata
     7621 tgccttaaat gcggcacgaa aggctgtcat ttttaatccc gattgagttt attattaatt
     7681 aggtcactgg cttactgcat ggttgcctta ataagcggag ttaatgcacc gtaatcattg
     7741 attgtctgaa aactgatatc cccggttaca gcatgcggga tatccaccga tacttcacct
     7801 tttggcggca ccatggtgtt tgggagattg ctatttcctg ctttcatatt tgttacggta
     7861 atgaagtagg gcgttggatt aataagagtg agtatgctac cgctgcgacg aaaccgaagc
     7921 attgcaggcg cttcttcagg tgccattgcc agatgcgtgg ggcgataaaa catttttatg
     7981 cggctaataa ttgccagctg taatgtattc tcattcttct ggtctttttc catagcaggg
     8041 atagctttaa cattaaccca gaacaggctt tcacggtcgc ctggtaactg atgattagtg
     8101 gcgttgatta tccgaagcgt attctctttt ttaccttgca tggaaaaaag cggtggggta
     8161 atgacaaact gggtatcttt ctggtcaccc gcattttcta tccatgactg aatgagatag
     8221 acactggcag gatcattatt cgtgacaggc aataaaacct gtttctggtt tgccggataa
     8281 attacccgcg tcgcaccaag tgcgacagct gcgttggcaa tggtgctatg gcaagcaaag
     8341 agaaataaaa gtaacactgt cgccataaag gaaacagagt agggggtacg cgtagtttgc
     8401 atctgatgca ttccaaccgt ttggttcatt gattctgaat caatcgcaca agcggcattt
     8461 accacttcac ctttaaaatg aattacaccg ccattaacag tggtcgttac tgattcatca
     8521 ccctcggctg cgcttaccgc agcagacgac atcgccaaca cagaaacgac aataataccg
     8581 acatgtttga gtttcataat tctccaaaat ttatatttaa gtagctgaat aaagagagtt
     8641 aacaattaag ttattctgtt attgcttata aaacaagaat cattcttgat tggatgttgc
     8701 cctgagaata tagtttccat ggttattaca tttcacgaag aatgataata tctttaaatt
     8761 acaaggacac ctattcacaa caattttatt gctgcacttg ttgtagagag tatttgtaaa
     8821 aacattttat gtcgctaaat aacatgacga tttcattatg catgttattt ataaacagcg
     8881 actaaacaga atattattgc gaacaaggga agtgtcagga aaggtcaaga ggtactaata
     8941 gtttatatgg ctataaacat tagctatggt taatgtttgc ctggtgaaac taactgaatc
     9001 ccatgaataa tgcagtaatt agtagtgctt tcatatctga tacctgtttt aaacgatata
     9061 tttggaagtt gacgaatatc ggaaatagct tcctccatca gctgtagtca ctgttctctg
     9121 tatttcacat tgcatatcaa cacgatatgc tgagattagc taacttgaga ttaaagataa
     9181 ttacacggcg ctatgaatta tattcagaag cgtgagggat atagtgccat caaagcgctg
     9241 gctgctgtaa acaacgcaat tatccagctc atggtctatg gtgtgccatc actgaacaga
     9301 ggttgatttt tctaccgaaa cgggagggaa gtcagaaatc acaacgtatt gatttatctg
     9361 tgtgtggatg tgaatggtga agtaaaggac cttcataatc aatttaacat aatatacatt
     9421 atgcgcacca atataaacca agggcgaatc cagtcgttgg cggttcatga ttgttctgct
     9481 cattaacaac gaccaaaacc ccatatctta cttaataccg tattctcggc ttaaccgatc
     9541 gtgcaacctc aacacattgg tttcaactgc cgtcaccacg ttctccggaa aatctgtcgg
     9601 taatgaagtc ttcacgttat ccagtgctgc cggaatcatt ctggcaaagt cactcaggat
     9661 ttcatgcatc tgcacttccg ggaatttcag cacctttgct gtcgccagaa aatgtcgcgg
     9721 ataaatttta tcgattgccg tttttttgcc tttggatgcg ttaagcccca ttgccagttt
     9781 gagatcgctg atgtgtattc ccgtaccgcc aaggaccgga aatgccgaaa tgatgtcgta
     9841 aaatggtgtg agccgataac tgccgccagc ctgaataaat acggagaagt tttttgcatg
     9901 gccatccgtt gcgccaatca accactggaa gacctgaaac ttcataaaat catagcgatc
     9961 tttcagcgcc tcgctggacc ccatcaaaaa agccataatt tgcgcgatac cggggcctcc
    10021 atctgattca tatttcaccg atgaaggtaa accgaatgtc tggcacatat cctcctgtgg
    10081 caagcgaagt aaaaccgttc gctcagtatt ccaacgcctg tcaaaacgtt cgaccgctaa
    10141 cgcgcgcacc cttcccgctt taatgatttc tgcgtccgga acattcaacc cgagttcttt
    10201 cgccagcagc aaacagtaat actcattatc aacgctttgg ctaagatcga gcgtcgcatt
    10261 gggctgtctg atttcgccaa tcggcaattt gataatgtgc gtcgttggcg ttattccctt
    10321 cggaatgcac cagtcattgc ctattctgag cagcgcagtc ttctcctgtg cgccagcaac
    10381 cgagatgcga aagtcatttt cttctctaat catgcctaac gggatatctg ctttataagc
    10441 cgttaatact tcttcaagtc tggcttcagt aagcttttcc catgccatta tcggacacgt
    10501 tacggtttca tcttcgggga ttaacgtcac ggcaccaacg ctgtctcgcc ctatttctga
    10561 caataaatca aacggttgtc tggatttagc atgataacgt ttaacgatcc ggtcacgtac
    10621 aatcgggcta tcgggtaaca ggttatcgaa gaagttaaat acggcatcag aggtgatatt
    10681 ccccctctgc aatggcagcg aaagtgacaa cggtctggca taacggctgg ctaaccactc
    10741 agctgcatac ttaaaggtgt gcgcgccgtt ggctaacttc gttaactcgc ctacccgctg
    10801 gttgttcatc caagtgacta gtttaggcat taccactcca gatcttgctg ttctgttgct
    10861 tctggcgagg catttttcgc gtcgcatagc gtcattgaga gttcaagcga ctgtaaaatc
    10921 ttaaaaaatg tcgtgagcga ggtattgtca ggattgtttt cgaaattgga aattgtcgcc
    10981 tgcttaatgc cgattttttt cgccaactcg ctctgcgtcc agccgttttg ctggcgaacc
    11041 agtttcattg cattcgccaa ttgcgttggg ctatagatct tctgaaagct catcatgtca
    11101 tacgtccaca gcaaatttat ccgcttaagg ggatattatc agttttatcc tttagtgagg
    11161 ataaagtcaa tctggaaaca catcttatcc gctctacggg ataaacgctg cgatatccgc
    11221 gatcgcggat aaaaaggagg atttaaaaaa gcacatccta atgcggtggc ttctttgact
    11281 accggaatct gtaatcttaa tgaccgggcc gcgtaaaaaa cgtctgttca atggggtgat
    11341 gccgtgaggc gaatttatca gttttatcta caattggggt aacgcgctga cgggagtaaa
    11401 aaaatgtctg actggaaccc ctctttatat ctgcactttg ccgctgaacg atcgcgtccg
    11461 gcggtggagc tgcttgccag ggtgccgctg gagaatatcg aatacattgc cgatcttggc
    11521 tgtggcccag gtaacatcac cgcccttcta caccaacgtt ggcctgctgc caggataacg
    11581 ggcatcgact catctccggc gatgattgct gaagcgcgca gtgctttgcc agactgcctg
    11641 tttgtggaag cagatatccg caactggcaa ccggaacagg cactcgatct gatttttgct
    11701 aatgcctcac tgcaatggct gcccgaccac tacgaattgt ttcctcattt ggtttcgtta
    11761 cttaattcgc atggtgtgtt ggcaatacag atgccagata actggctaga gccaacccat
    11821 gtgctcatgc gcgaagtcgc ctgggaacaa aattatccgg atcgcgggcg tgagccgctg
    11881 gctggcgttc atgcttacta cgatattctg agtgaagccg gatgtgaggt cgatatctgg
    11941 cgaaccactt actatcacca gatgccgtcg caccaggcga ttatcgattg ggtgaccgcc
    12001 actggattac gtccgtggtt acaggatctg accgagagcg aacagcagca ttttcttacg
    12061 cgctaccatc agatgctgga agagcaatat cccctccagg agaacggaca gatattgctg
    12121 gcatttccgc gtctgtttat tgttgcccgc cgtacggagt aattatcacg tcagctggta
    12181 atggcgatcg ggaagaattt tcgctggaat ttctgcttca tcattcatct gtaacaggtc
    12241 aatttcaata gcgttgcaga tggcatccag cggtaaatca ttgttttcag taccgaaggg
    12301 atcttccagt tcttccgcca gacaatccag cgaaataaaa gtgtaggaaa tcagcacaga
    12361 gataaaaggc gtcatgtaat gcaggtccac gaccagcgca aacggcaaca tgatacaaaa
    12421 cagatacacg gtgcgatgca aaatcagggt gtaggcaaag ggaattggcg tataggcaat
    12481 gcgctcgcat cctgccagga ccgctgaaat atcattaagc cgatcgttga ggctaataaa
    12541 caggatatct gaaagttgtc cattgcgtcg ctgaaccgcc aaccactccc ccattattaa
    12601 caagatgcgg ttagctggag agttagaagc cagtacacgc tgaagatctt cagtcttgag
    12661 ataatgagcc agcacttctg cctgtggctg tttgcgtaat gtcatgcgta aacagtgggc
    12721 gaagacgatt tgcagccggg caaactccct tacacttgcc gaatccggta atgtcgtttt
    12781 tacctcgcgc agtaacgacc gcgaggcaat catcaactgc ccccaaagtt ttcgcgcttc
    12841 aacgtaacgg gcgtaaccgg cattattacg aaaaccaaga aaaatggcga tggcgacacc
    12901 gagaatgctg aacggtgcga gggtgaattt aatgcccaaa tgcgtgtacc agggcagcat
    12961 gaaaataaca gcgatcgaaa agagaaaatt gagtagtaag cgcgaggata tcttggataa
    13021 tactgaaccg tgccagacaa aaatacggcg cagccagtgt tgttgtggac gaacaatcat
    13081 ggttatcttc aggcgtggaa aagtcgccct attaaacgtg attatgatca cattctcaag
    13141 atactactta caaattacct acaagattac aacattaaca ggtgctgcat gtggcacctg
    13201 ttaatgataa aggcatatag aatgttgtaa ctaatatagc ggaataagaa acccggtcga
    13261 aaccgggttc agagtattag cacaacgggc gtacagcttc gcgcatccct ttttcgagaa
    13321 tcgcatccag gtcattagca acctgctcga ccagaccagg cacttgcgtc aggtcctgct
    13381 cccagtggtc tttttctgcc aacacaatcg ctaccagttc ctgggtcccg ataacacggt
    13441 cacgatactg gctccagagt tgctgataac gttccagcca gtgtgcatcg tcctgtaccg
    13501 gatatgtttc tccattacgc acaccgcgat agaacgcaat caatgccgct aatgcgaaag
    13561 taaggcgcgc cggaagtgtg ccgtttgcct tctgccctgc cagcagctgc ggcaggatgc
    13621 gtgtgcggaa cttggtcata ccgttgagcg cgatagacag cagttgatgc ttgatgtacg
    13681 ggttacggaa acgtccggtg actgcactgg cgaaagactc cagctcatcg cgtggcaaat
    13741 ccagtaccgg aataatttct tcgtagatgg ctttttcaac gaatgcgcaa atttcagcat
    13801 cgttcatcgc ttcacctacg gtatccagcc ctgcctggaa cgccaccggc accagcgcgg
    13861 tgtgcgcacc gttgaggatt gccactttgc gttctttata cggtttaata tcgtcaacga
    13921 tcagcacgtt aagcggatat ttgtccagac gaagttcagt cgctaaggat ttcggcccct
    13981 gaatcacaaa caggtaaaag tgttcagcgg tgtcgaggaa accatcgtgg tagcccagtt
    14041 cttcttccag tttagccact tcatcacgcg gataaccggt aacgatacgg tccaccagcg
    14101 tagaacagaa gctgttagcc tgatccagcc attgaataaa tgcttcaggc aatgcccact
    14161 cttgcgcata gcgcagcacc agttcacgca acgcgtcgcc attatagtca atcaactcac
    14221 acgggatgat gatccaacct ttatccagcg caccgttgaa atggctaaaa cgttcgaaca
    14281 gcagacgggt cagttttgcc ggataactta ccgctggcgc gtcatcgaat ttatcgcccg
    14341 catggtagct gatacccgct tcggtggtgt tagagaaaac aaagcgcatt tccgggttgt
    14401 gagccagttt caggaattca tcgtattcac tatagacgct gatttcacga ttaaccgagc
    14461 gaatcagacg cgcgtcgctg accgcttcac ccttctcatt caggccacgg ataatggtgg
    14521 tatacagacc atcctgcgtg ctcagtgacg gcgggaatga agtttcaatc ggacgaacaa
    14581 cgaccacgcc agaattcaga tcggtgtgct cattcaggag atcgatttgc cagtcaacaa
    14641 aggcgcgcag gaagttacct tcaccaaact gaatgatacg ttctggatac tgtgcaccgg
    14701 gaaaatcgcg acgatttagt gttttcacaa tgggttccct tctgattagt catacaacct
    14761 gtttgaattg gtacgacagg ttagcaaact ttaatacgtc gaacccctgt tttgatcaac
    14821 tcctgatgat taatgagcag ttttatgaga aaagtgtggc gcggatcatg gtttaatcga
    14881 ggaaacaggc cttttcttgg atcataaagt ggtagaacac attgcattta attcgctctg
    14941 agtaaataaa gatgtcagac aacttcctca ccgtaacgca tagtgctggt acggttgcgc
    15001 ccatctttct tcgagcgata cagacacgta tcggcttcga ccatcaattt attaaagtca
    15061 tcggtcagcg ttcggtacga tgcgcaacca ctaccgacgc caatacttac cgtgagataa
    15121 agcgtttttt gttgccaggt gaacggttgc agttcaacgc ctttacggat tttttccgcc
    15181 attagcaggc catcgacagg attcacagac ggcactgcaa cagcaaattc ttcgccgccc
    15241 attcgcgcca ccagcccctt atcaccgaca atcttctgaa tatgctgggc aaacacgctt
    15301 aacactttat cgccacattc atgtccatag ttatcgttaa tgcttttgaa atagtcgata
    15361 tcaagcagca tgaccgtcag atgttgtgtc tgtttcagcg atggactttt cagcgcctca
    15421 taaagaccgg accgtgagta aacctgggtc agaaaatcaa aatcggctcg cagcgcaact
    15481 tgcttcatta gcgaattgat cgctgccacg ctaaaggaaa ccataattgg gcatatcgcc
    15541 atcgtggcaa taccgagacg tgcggagaac atttgcggaa tggagaacgg cgaaccgacc
    15601 gagatatcaa tcaccgaatt tgccaccagt acgacttcca cagcgccggt gacaaaggtc
    15661 aacagacatg ttacttgcgg cgtatagcgc actgcacacc agattaatgc agggagcgga
    15721 aacgccagac tccccgctcc gccaatgact accgaggcaa taaccgacac aataagcgcg
    15781 atagcaggca tcatctgctc tgctttaaag cgcggcagca ctccaggaat tgccaacgtc
    15841 agcatacaag gcacgatcaa cacgcccgtt gagaattgct cactaaacca gtcggcaagc
    15901 aaaggccaga aatccagagt atcaatactg accgaaccaa tcgccccgac aatagcgcat
    15961 aataatgcgg caagcagaca gtaattaaat aaccgtaagg cacttactgg ctcatactta
    16021 ttttttccca gacgcttatc ccgcgcgacc agtaaggcga cggtaacaat aaacatcata
    16081 ttggagaaat tgatagccag tgaaaccagc ccccattcgg tggttatggc atcataaacc
    16141 agcatcgcca cataactgat cgcatagtaa tgcagtcgat taagccagac atagcgggca
    16201 aacacccccg ccattacgcc attcagcggc cagaaaagag aaagttcgtg aaccagccgt
    16261 aactctgcac caataaaata gaacagcgtg gttagcacaa aaatagcgat gctattacgt
    16321 agcagatgac cttcctggaa caaacggaaa gttgaaatgg gctgtacatg cattaattat
    16381 ctgtccatac aattgcgggt ggcaattatc tcaacgcaat aagtaaattc ttagaaagga
    16441 tagcatgttc gctgacaacg gcggcaacta aagataccta atgaatgcca ttttatcgat
    16501 ttccgtaatt atcatggctg attcatctgt ataaccagcc agtgatagat taccgtcaca
    16561 atataacgtt gttgctcctc acttaacgct tccccctgag gaatgttatg ccacttagcc
    16621 agacaaccgc gacaacaggt cgcggtggcg tgttgagcga taaaaaccgg atgcccgcgc
    16681 atgggggttt gcttaccgtc gttagccggt aatgccggag caagacgttt agcgacaaaa
    16741 tctgccgcat gttgttcaat gactggcgcg cctttctcca gacaatactg acgctctttc
    16801 acacccaaac gaaagcgaga gcgaaatttt gaacgggata aacgcgcgaa gagtggatcg
    16861 agagactgca ttaataaact gaacgcccta attgtttcgt caattgttca aggacggcaa
    16921 tgcccgcaag cgagttaccg gcatcatcca gttccggact ccagacagcg atggccattt
    16981 catgcggaac aatcgccaca ataccgccac caacgccaga ttttgccggt agtcccaccc
    17041 gccaggcaaa ctcccccgcg ttctggtaca taccgctggt cgccatcagc gcgttaattt
    17101 gccgcgcctg cattggcgtc accacaggtt catcaatatg aatagctttc ccctgattcg
    17161 ccagaaagac aaacgtccgg gccagctcta cacagctcat tttcagagcg cagtaatgaa
    17221 agtagttttg cagaacggtt gtcacgtcat gatggaaatt gccaaacgac ttcatcagcc
    17281 aggcgatagc cgcatttcgc gcggaatgtt caaattcgga acgcgctacc accgtatcgt
    17341 aggaaatatc agacacacca cttaagccgc gcacgacttc cagcatacgt tgccgaggtg
    17401 cgcttaatcg cccttgcaac atatcgcaga ccaccagcgc accggcatta ataaacggat
    17461 tacgcggaat accctgctcc atttccagtt gcactaaaga attgaatggt gatccagacg
    17521 gatctttgcc gacgcgttgc cagatttcct cttcggagta atgacgcatg gcgacaacga
    17581 gactcagcac tttggaaata gactgaatgg aaaaacgttc ttgcgcgtct ccggcctgaa
    17641 aaagctgtcc gtcaacggta cagatagcaa tccccaatcg ggaaccgtct accgtagcca
    17701 gcgccggaat ataatccgcg actttaccct gaccaatgag cggccgcact tgccgcaaga
    17761 tgttttctaa aattgcatta tccatggcga ctgccacttt ctactcctgg accgcaggtc
    17821 tgaaaagacc tgcgagtata tcagagctga atatatagcg tcagacccgg tctttccaca
    17881 ccgtctggat attacagaat tcgtgtaagc cgaaatggga aagctcacga ccaaagccac
    17941 tcttcttcac gccaccaaag gcgactcgcg catcgctggc acaataacca ttgataaaca
    18001 ccccaccgca ttccagacgt gccgccatct gtctggcctg tgtttcgtcg gtggtgaaaa
    18061 tggtcgctga aaggccgaac tcactatcat tagccagttc cagcgcatgt tctgcatctt
    18121 tcgcaatggt gattgccgca acggggccaa acatttcttc ccgaaacgcg gtcatttctg
    18181 gggtaacatt cgccagaacc gttggcggat agtagttacc tgccccagcc atcttttccc
    18241 cgcccagtaa caaacgcgca ccctgcgcca gtgttttttc cacctgatga tgcagctcat
    18301 cacgtaaatc aaaacgagcc attggtccga gagcgttgtc ttcatcacgg ggatcgccca
    18361 ttttcaaggc tgccgcagct gccacaaaac gttcggtaaa tgccgaagca attccctctt
    18421 cgatgataaa gcgttttgcc gctgcacaaa cctgtccggt attctgataa cgtccggcta
    18481 ccgccgcttt caccgccagt tccagatcgg catcgttaag cacaataaac ggatccgaac
    18541 cacccagttc cagtacgcat tttttcagtg ccgctccagc ctgtgcgcca atagccgctc
    18601 cagcacgaac acttccggtc actgtgacag cagcaatgcg cgaatcttta atcatctgac
    18661 tgacaccgtc gttgtcggca ttcagccagc catatacgcc ttgtgggata cccgcatctt
    18721 taaacacctg ggcaacgagc tgtgcacagc ccatcacatt cggcgcatgt ttaagtaagt
    18781 agccgttacc agcaagaatg atgggaacag cgccacgcat cacctgccat aacggaaaat
    18841 tccacggcat aatcgccaga atcgtcccca acggtcgata ctcaataacc gcctgctgat
    18901 tttccaccag cgtaggttct gccttcagca ttgccggacc atgttctgca taccagtcac
    18961 acaaattcgc cgatttcgcc acttcagcgc gcgcctggtt gattggtttg cccatttcac
    19021 gggtgatcat ttgcgccatt tcttcgctac gggcgcgcag agccttaccg atatcacgca
    19081 gtttttcagc acgataatct atatttgtct cgcgccagtc gcgaaagcct gctgccgcca
    19141 gctgaagtgc gttttcgata tcgtcaacac cagcccacgg cagcacagaa agttgttcac
    19201 cggtggcagg atttatcgaa attgcatgag ttgccggagt aatggtcatc ggggtatctc
    19261 ctttatgagt catggtatga agatacgcag atttactctt gctttaaaat gaataatatt
    19321 aagccactta ttcacgaatc gagaatgcca tggatctgac ccaactggag atgttcaacg
    19381 cggttgccga agctggcagc attacccagg ctgcagcaaa agtgcatcgc gtgccgtcga
    19441 atctcactac ccgtctacgt cagctggaaa cagaactggg ggttgatctg tttattcgcg
    19501 agaatcagcg tttacgtctc tcgcctgccg ggcataactt tttacgctat agccaacaaa
    19561 ttctcgcatt agtggatgaa gcgcggagcg ttgtcgctgg cgatgagccg caaggtttat
    19621 tttctctggg atcgctggaa agcaccgctg cagtgcgcat tccggccacg ctggcggaat
    19681 ttaaccgtcg ttatcccaaa attcagtttt cactttccac cggcccttcc ggcactatgc
    19741 tggaaggtgt gctggaggga aaactgaatg cggcgtttat tgatggaccc attaaccata
    19801 ctgccatcga cgggataccg gtataccgcg aggaactgat gatcgtcacg ccacaaggac
    19861 atgcgccagt aacccgtgcc agtcaggtga atggcagtaa catttatgcc ttccgcgcca
    19921 attgttcgta tcgtcgccac ttcgaaagct ggtttcatgc tgacggtgcc gctccgggaa
    19981 ctattcacga gatggagtct tatcacggga tgttggcctg tgtggtcgca ggagcaggca
    20041 ttgcgcttat tccacgctct atgctggaaa gtatgccggg gcatcaccag gttgaatcgt
    20101 ggccgttagc tgagcaatgg cgttggttaa caacctggct ggtctggcgt cgtggtgcga
    20161 aaacgcgtcc gcttgaggca tttattcaac tgctggatgc gcctgactcg gcaaaacagg
    20221 gttaccaatg agctattttt gatagttcat gcggctaata tgctctatat agtgatgttc
    20281 caatgactta tgactatatg gggcaaatat ggttacgcca gtaagcatca gcaattacat
    20341 atctcttcct gatgattttc ccgttcgtaa tattgcacct caagtaaaag aagaacaggc
    20401 ccccttcctg atcgtcatta aaatgtgatg ttaacaactc tctgatgcgt gacagaacaa
    20461 ccgtcagaga gatggaaatg cgatccagat cacaaatgca ttgtattcac atcattaacc
    20521 gttttaagat catttcatca ctttttcgca actcacccga taatctgtta tgacaacaaa
    20581 cactgtttcc cgcaaagtag cgtggctacg ggtcgttacg ctggcagtcg ccgcctttat
    20641 cttcaatacc accgaatttg tccctgttgg cctgctctct gacattgcgc atagttttca
    20701 catgcaaacc gctcaggtcg gcatcatgtt gacaatttat gcatgggtag tggcgctaat
    20761 gtcattgcct tttatgttaa tgaccagcca ggttgaacgc cgcaaattac tgatctgcct
    20821 gtttgtggtg tttattgcca gccacgtact gtcgttttta tcgtggagtt ttaccgttct
    20881 ggtgatcagt cgcattggtg tggcttttgc acatgcgatt ttctggtcga ttacggcgtc
    20941 tctggcgatc cgtatggctc cggccgggaa gcgagcacag gcattgagtt taattgccac
    21001 cggtacagca ctggcaatgg tattaggttt acctctcggg cgcattgtgg ggcagtattt
    21061 tggctggcga atgaccttct tcgcgattgg tatcggggcg cttcttaccc ttttgtgcct
    21121 gattaagtta cttcccttgc tgcccagtga gcattccggt tcattgaaaa gcctcccgct
    21181 attgttccgc cgcccggcat tgatgagcat ttatttgtta actgtggtgg ttgtcaccgc
    21241 ccattacacg gcatacagct atatcgagcc ttttgtacaa aacattgcgg gattcagcgc
    21301 caactttgcc acggcattac tgttattact cggtggtgcg ggcattattg gcagcgtgat
    21361 tttcggtaaa ctgggtaatc agtatgcgtc tgcgttggtg agtacagcga ttgcgctatt
    21421 gctggtgtgc ctggcactgc tgctacctgc ggcgaacagt gaaatacacc tcggggtgct
    21481 gagtattttc tgggggatcg cgatgatgat catcgggctt ggtatgcagg ttaaagtgct
    21541 ggcgctggca ccagatgcca ccgacgtcgc gatggcgcta ttctccggga tatttaatat
    21601 tggaatcggc gcgggtgcgt tggtaggtaa tcaggtgagt ctgcactggt caatgtcgat
    21661 gattggttat gtgggcgcgg tgcctgcttt tgctgcgtta atatggtcaa tcatcatttt
    21721 tcgccgctgg ccagtgacac tcgaagaaca gacgcaatag ttgaaaggcc cattcgggcc
    21781 ttttttaatg atacgtttta atgatttcca ggatgccgtt aataataaac tgcacgccca
    21841 tacataccag caggaatccc atcagacggg agatcgcttc aataccaccc ttgcccacca
    21901 gccgcataat tgcgccagag ctgcgtagac ttccccacaa aataaccgcc accaggaaaa
    21961 agatcagcgg cggcgcaacc atcagtaccc aatcagcgaa ggttgaactc tgacgcactg
    22021 tggaggccga gctaataatc atcgcaatgg ttcccggacc ggcggtactt ggcattgcca
    22081 gtggtacaaa agcaatattg gcactgggtt catcttccag ctcttccgac ttgcttttca
    22141 cttccggtga atcaatcgct ttctgttgcg gaaagagcat ccgaaaaccg ataaacgcga
    22201 cgatcaaacc gcctgcaatt cgcagaccgg gaatcgaaat gccaaatgta tccatcacca
    22261 gttgcccggc gtaatacgcc accatcatga tggcaaatac gtacaccgag gccatcaacg
    22321 actgacgatt acgttcggca ctgttcatgt tgcctgccag gccaagaaat aacgcgacag
    22381 ttgttaatgg gttagctaac ggcagtaaca ccaccagccc caggcctatt gctttaaaca
    22441 aatctaacat tggtggttgt tatcctgtgt atctggttta tcagcgaaaa gtataagggg
    22501 taaacaagga taaagtgtca ctctttagct aaccttgcat cgcattgacc aaaacttgaa
    22561 ccgatttagc aaaacgtggc atcggtcaat tcattcattt gacttatact tgcctgggca
    22621 atattatccc ctgcaactaa ttacttgcca gggcaactaa tgtgaaaagt accagcgatc
    22681 tgttcaatga aattattcca ttgggtcgtt taatccatat ggttaatcag aagaaagatc
    22741 gcctgcttaa cgagtatctg tctccgctgg atattaccgc ggcacagttt aaggtgctct
    22801 gctctatccg ctgcgcggcg tgtattactc cggttgaact gaaaaaagtg ttgtcggtcg
    22861 acctgggggc actgacccgt atgctggatc gcctggtctg taaaggctgg gtggaaaggt
    22921 tgccgaaccc gaatgataag cgcggcgtac tggtaaaact taccaccagc ggcgcggcaa
    22981 tatgtgaaca atgccatcaa ttagttggcc aggacctgca tcaagaatta acaaaaaacc
    23041 tgacggcgga cgaagtggca acacttgagc atttgcttaa gaaagtcctg ccgtaaacga
    23101 aaaaagaggt atgacgatgt ccagacgcaa tactgacgct attaccattc atagcatttt
    23161 ggactggatc gaggacaacc tggaatcgcc actgtcactg gagaaagtgt cagagcgttc
    23221 gggttactcc aaatggcacc tgcaacggat gtttaaaaaa gaaaccggtc attcattagg
    23281 ccaatacatc cgtagccgta agatgacgga aatcgcgcaa aagctgaagg aaagtaacga
    23341 gccgatactc tatctggcag aacgatatgg cttcgagtcc caacaaactc tgacccgaac
    23401 cttcaaaaat tactttgatg ttccgccgca taaataccgg atgaccaata tgcagggtga
    23461 atcgcgcttt ttacatccat taaatcatta caacaactag ttgataacgt gacaacgtca
    23521 ctgaggcaat catgaaacca cttttatccg caatagcaac tgcgcttatt ctcttttctg
    23581 cgcagggcgt tgcggaacaa accacgcagc cggttgttac ttcctgtggc aatgtcgtgg
    23641 ttgttccccc atcgcaggaa caaccaccgt ttgatttaaa tcacatgggt actggcagtg
    23701 ataagtcgga tgcgctcggc gtgccctatt ataatcaaca cgctatgtag tttgttctgg
    23761 ccccgacatc tcggggctta ttaacttccc acttttaccg ctttacgcca ccgcaagcca
    23821 aatacattga tatacagccc ggtcataatg agcaccgcac cgaaaaattg cagacccgtt
    23881 aagcgttcat ccagcaatag tgccgcactt gccagtccaa ctacaggcac cagtaacgat
    23941 aacggtgcaa cccgccaggt ttcatagcgt ccaagcagtg ttccccagat cccataacca
    24001 acaattgtcg ctacaaatgc cagatacatc agagacaaga tggtggtcat atcgatagta
    24061 accagactgt gaatcatggt tgcggaacca tcgagaatca gcgaggcagc aaagaaggga
    24121 atgattggga ttaatgcgct ccagattacc agcgacatca ccgccggacg cgttgcgtgc
    24181 gacatgatct ttttattgaa gatgttgcca cacgcccaac taaatgctgc cgccagggtc
    24241 aacataaagc cgagcatcgc cacatgctga ccgttcagac tatcttcgat taacaccagt
    24301 acgccaaaaa tcgctaaggc gatccccgtc aattgtttgc catgcagtcg ctcaccgaaa
    24361 gtaaacgcgc caagcacgat agtaaaaaac gcctgtgcct gtaacaccag cgaagccagt
    24421 ccagcaggca taccaaagtt aatggcgcag aacagaaaag caaactgcgc aaaactgatg
    24481 gttaatccat accccagcag caaattcagt ggtactttcg gtcgtgcgac aaaaaagatg
    24541 gccgggaaag caaccagcat aaagcgcaaa ccggccagca tcagcggtgg catgttatga
    24601 agccccactt tgatgaccac aaaatttagc ccccatacaa ccactaccag tagcgccaac
    24661 accccatctt ttcgcgacat tctaccgcct ctgaatttca tcttttgtaa gcaatcaact
    24721 tagctgaatt tacttttctt taacagttga ttcgttagtc accgtttacg acggcattaa
    24781 tgcgcaaata agtcgctata cttcggattt ttgccatgct attcctttac atctctaaaa
    24841 caaaacataa cgaaacgcac tgccggacag acaaatgaac ttatccctac gacgctctac
    24901 cagcgccctt cttgcctcgt cgttgttatt aaccatcgga cgcggcgcta cgctgccgtt
    24961 tatgaccatt tacttgagtc gccagtacag cctgagtgtc gatctaatcg gttatgcgat
    25021 gacaattgcg ctcactattg gcgtcgtttt tagcctcggt tttggtatcc tggcggataa
    25081 gttcgacaag aaacgctata tgttactggc aattaccgcc ttcgctagcg gttttattgc
    25141 cattccttta gtgaataacg tgacgctggt ggtgctcttt tttgccctta ttaactgcgc
    25201 ctactccgtt tttgctaccg tgctgaaagc ctggtttgcc gacaatcttt cgtccaccag
    25261 caaaacgaag attttctcaa tcaactacac catgctcaac attggctgga ccatcggtcc
    25321 gccactcggc acgctgttgg tgatgcagag catcaatctg cccttctggc tggcagctat
    25381 ctgttccgcg tttcccatgc ttttcattca aatttgggta aagcgcagcg agaaaatcat
    25441 cgccacggaa acaggcagtg tctggtcgcc gaaagtttta ttacaagata aagcactgtt
    25501 gtggtttacc tgctctggct ttctggcttc ttttgttagc ggcgcatttg cttcatgcat
    25561 ttcacaatat gtgatggtga ttgctgatgg tgattttgcc gaaaaggtgg tcgcggttgt
    25621 tcttccggtg aatgctgcca tggtagttac gttgcaatat tccgtaggcc gccgccttaa
    25681 cccggctaac atccgcgcgc tgatgacagc aggcaccttc tgtttcgtca tcgggctggt
    25741 cggttttatt ttttccggca acagcctgct aatgtggggt atgtcagctg cggtatttac
    25801 tgtcggtgaa atcatttatg cgccgggcga gtatatgttg attgaccata ttgcgccgcc
    25861 aggaatgaaa gccagctatt tttccgccca gtctttaggc tggcttggtg ctgcgattaa
    25921 cccattagtg agtggcatag tacttaccag tctgccgcct ttctcgctgt ttatcatctt
    25981 agcgttggtg atcgttgttg cgtgggtgct gatgttaaaa ggaattcgtg caagaccgtg
    26041 ggggcagccc gcgctttgtt gatttaagtc gaacacaata agaatttaat tcagccttcg
    26101 tttaggttac ctctgctaat atctttctca ttgagatgaa aattaaggta agcgaggaaa
    26161 cacaccacac cataaacgga ggcaaataat gctgggtaat atgaatgttt ttatggccgt
    26221 actgggaata attttatttt ctgggtttct ggccgcgtat ttcagccaca aatgggatga
    26281 ctaatgaacg gagataatcc ctcacctaac cggccccttg ttacagttgt gtacaagggg
    26341 cctgattttt atgacggcga aaaaaaaccg ccagtaaacc ggcggtgaat gcttgcatgg
    26401 atagatttgt gttttgcttt tacgctaaca ggcattttcc tgcactgata acggatcgtt
    26461 gacacagtag catcagtttt ctcaatgaat gttaaacgga gcttaaactc ggttaatcac
    26521 attttgttcg tcaataaaca tgcagcgatt ccttccggtt tgcttaccct catacattgc
    26581 cctgtccgct cttccaatga ccacatccag aggctcttca ggaaatgcac gactcacacc
    26641 agcagtcacg gtaatgttga tatgcccttc agaatgtgtg atggcatggt tatcgactaa
    26701 ctggcaaatt ctgacacctg cacgacatgc ttcttcatca ttagtcgctt tgacaataat
    26761 gataaattct tcgcccccgt agcgataaac cgtttcgtaa tcgcgcgtcc aactggctaa
    26821 gtaagttgcg agggtgcgta atactacatc gccgattaaa tgcccgtagg tatcattaac
    26881 caatttaaat cggtctatat ccaacaacat taaataaaga ttcagaggtt cagcattgcg
    26941 taactgatga tcgaaggatt catcaagaac ccgacgaccc ggcaatcccg tcagaacatc
    27001 catattgcta cggaccgtaa gcaaataaat tttgtaatcg gttaatgccg cagtaaaaga
    27061 aagcaaccct tcctgaaaag cgtcgaaatg cgcgtcctgc cagtgatttt caacaatagc
    27121 cagcattaat tcccgaccac agttatgcat atgttgatgg gcagaatcca ttagccgaac
    27181 gtaaggtaat tcatcgttat cgagtggccc cagatgatca atccaccgac caaactggca
    27241 cagtccataa gaatggttat ccgttatttc tggcttactg gcatctctcg cgaccacgct
    27301 gtgaaacata cttaccagcc actggtagtg ggcatcgata gccttattga gatttaacaa
    27361 gatggcatca atttccgttg tcttcttgat cattgccact cctttttcac agttccttgt
    27421 gcgcgctatt ctaacgagag aaaagcaaaa ttacgtcaat attttcatag aaatccgaag
    27481 ttatgagcat ctctgagata acattgtgat ttaaaacaaa atcagcagat aaaaaagtgt
    27541 ttaattctat aaattaactc tgcattatcg caattaaaag gatgacaaat agcataaccc
    27601 aataccctaa tggcccagta gttcaggcca tcaggctaat ttatttttat ttctgcaaat
    27661 gagtgacccg aacgacggcc ggcgcgcttt tcttatccag actgccgcta atgttgatca
    27721 tctggtccgg ctgaatttga aaattattat aacggaagag tatacaaaaa aagtaatttt
    27781 gctggcgact gcgaaacggc attcgcatta gcggtgaagt ttgccctcgc ccagcggctg
    27841 caattactgc tataacgagg ctggtctggc gataaatcca ggccagccat tggtggtgtt
    27901 tatacgttca agccacgatg ttgcaacatc ggcataatct gaggtgcctt accgcgccat
    27961 tgtcggtaca ggcgttccag atcttcgctg ttacctctgg aaagaatcgc ctcgcgaaaa
    28021 cgccgcccat tttcacgcgt taatccgccc tgctcaacaa accactggta accatcatcg
    28081 gccaacattt gcgtccacag ataagcgtaa taacctgcgg catatccgcc accaaaaata
    28141 tgggcgaaat aactgctgcg atagcgtggc ggtatagcag gaagatccat attttccgcc
    28201 accagcgccc gcaattcgaa atcatcgaca tcctgcattg cttcgttttc ttccaggcaa
    28261 tgccagcgca tatcgagaag tgcggcgcta agcagttcgc tcatctcata ccctttattg
    28321 aacaggctgg cattacgcat tttctgttga agttcgtcag gcattgcggt cccgctctga
    28381 taatgccggg cgtagcgagc gaatacctgc ggatgtgttg cccagtgttc gttgatttgc
    28441 gacggaaatt cgacaaaatc acgcggcgtg ttggtgccgg aaagcgtggc ataacgctgg
    28501 cgggcaaaaa ggccgtgcag cgtatgacca aattcatgga ataaggttat tacatcatcc
    28561 cagagtaaca acgcaggctc accggcagcg ggtttctgat aattgcagac gttataaatt
    28621 accgggtgcg tttcattcag cgttgattgc tcaacaaaat tgcccatcca tgcgccgccg
    28681 ctttttgaat cacgggcgaa gaaatcaccg taaaataacg ccagccccac gccattatga
    28741 tcaaaaattt cccacacacg aacgtcagga tggtagacag gaatatcaaa acgttcgaca
    28801 aacttaatac cgaagagctg attcgcagtc cagaatacgc cttcattcaa caccgtgttt
    28861 aattcaaaat atggcttgag ctgcgcttca tcgagatcga atttctcacg tcttacctgc
    28921 tcggcataaa atgcccagtc ccacggctgc gcgctaaacc cgccctgctg cttatcgata
    28981 accgcctgta tggaggctaa ttcatcgctc gcacgttgac gcgccgctgg aacaatttcc
    29041 cgcataaagt tgagcgctgc ttctggcgtt tttgccatct gatcggcgat tttccatgcg
    29101 gcataatgag gaaaaccaag cagtttcgcc tgctgcgcgc ggatctccac cagacgttga
    29161 atgatagcgc gggtatcatt ggcatcattt ttttccgctc gcctccagcc cgcagtaaac
    29221 agtttttcac gcgtcgcgcg atcgcgcagt tcagcaagcg ctggttgctg ggtggtattc
    29281 agcagcggaa tcagccagtt gttatccaga cctttctcgc gagccgcctc tgccgccagc
    29341 gcaatctctt gttcactcat tcctgccagc tgcgcgatat cgttcacaac cagaccgccg
    29401 gatttatttg ctgccagtaa ccgctggtta aactggctgg tcagggtcgc agcttctgta
    29461 ttcagtactt ttaattttgc tttatcagct tgctcaagtt tggctccggc aaggacaaaa
    29521 cgttgatgaa tcacctccac caggcggatg gattcactat caagccccag ggattcacgg
    29581 cgttgccaga cagcatctac ccgcgcgaat aattccccgt tcagatagat atcattcgca
    29641 agttccgcca gttcagcgga aaactgttca tcaagacgct gtaattcatc attggtatgc
    29701 gccgcagtca tcgcaaaaaa gacgctggta acgcgggtaa gtaattctcc gctttgttcc
    29761 agtgccagaa tagtattgtt gaaatcaggt gtttgcgggt taagcgcgat ggcagcaatt
    29821 tctgcccgct tttgctgcat tccctcatcg aatgccgggc gatagtgatg attggcaatt
    29881 tgatcaaaat ggggagccag atacggcagt gtgctttgca caaggaaagg attcattgtt
    29941 gtcattttct tctcctgaac gcgaggtgtt ccatagcgta ggcttactga taacggagtg
    30001 caatcttgca aaccagtatt acccgctctt aagcatcacg tgctatgtta ttgacacaca
    30061 aaatcgttga ggaacagtga gatgatcgtt ttagtaactg gagcaacggc aggttttggt
    30121 gaatgcatta ctcgtcgttt tattcaacaa gggcataaag ttatcgccac tggtcgtcgc
    30181 caggagcggt tgcaggagtt aaaagacgaa ctgggagata atctgtatat cgcccaactg
    30241 gacgttcgca accgcgccgc tattgaagag atgctggcat cgctccctgc cgagtggagc
    30301 aatattgata tcctggtaaa caatgccggc ctggcgttgg gcatggagcc tgctcataaa
    30361 gccagcattg aagactggga aacgatgatt gataccaaca acaaaggcct ggtatatatg
    30421 acgcgcgccg tcttaccggg tatggttgaa cgtaatcatg gtcatattat taacattggc
    30481 tcaacggcag gtagctggcc gtatgccggt ggtaacgttt acggtgcgac gaaagcgttt
    30541 gttcgtcaat ttagcctgaa tctgcgtacg gacctgcatg gtacggcggt gcgcgtcacc
    30601 gacatcgaac cgggtctggt gggtggcacc gagttttcca atgtccgctt taaaggcgat
    30661 gacggtaaag cggaaaaaac ctatcaaaat accgttgcat tgacgccaga agatgtcagc
    30721 gaagccgtct ggtgggtgtc aacgctgcct gctcacgtca atatcaatac actggaaatg
    30781 atgccggtta cccaaagcta tgccggactg aatgtccacc gtcagtaatt tttatacccg
    30841 gcgtaactgc cgggttattg cttgtcacaa aaaagtggta gactcatgca gttaactcac
    30901 tcacaagcaa gaacgaatga ccgtcgaaac gcaacttaat cccacacagc ctgtcaatca
    30961 gcagatttat cgtattcttc gccgcgacat tgtccattgc ctgattgcac caggcacacc
    31021 gttgtcggaa aaagaagttt ctgttcgttt caatgtgtca cgccagccgg ttcgtgaagc
    31081 ctttattaaa ctggcggaaa acggtctgat tcaaattcgt ccgcagcgtg gcagctacgt
    31141 caacaaaatt tccatggccc aggtgcgcaa cggcagtttt atccgtcagg ccattgagtg
    31201 cgcggtggcg cgtcgggcgg cgagcatgat taccgaaagc cagtgctacc aactggaaca
    31261 aaatcttcac cagcaacgca ttgccattga gcgcaagcaa ctggatgatt tttttgaact
    31321 tgatgacaac ttccatcaac tcctgacgca gattgccgac tgtcaactgg cgtgggatac
    31381 cattgagaac ctgaaagcga ccgttgatcg cgtgcgctat atgagcttcg accacgtttc
    31441 tccaccagaa atgctgttac gccagcatct tgatattttc tctgccctgc aaaaacgtga
    31501 tggcgatgcg gtagaacgtg caatgacgca acatttgcag gaaatcagcg aatccgtgcg
    31561 ccagatccgc caggaaaaca gcgactggtt tagcgaagag taattcattt cctctcatcc
    31621 catccggggt gagagtcttt ccccccgact tatggctcat gcatgcatca aaaaagatgt
    31681 gagcttgatc aaaaacaaaa aatatttcac tcgacaggag tatttatatt gcgcccgtta
    31741 cgtgggcttc gactgtaaat cagaaaggag aaaacaccta tgacgaccta cgatcgtaac
    31801 cgtaacgcaa tcaccactgg cagccgtgtt atggttagcg gcaccggtca cactggcaag
    31861 atcctgtcga ttgatactga aggtctgacc gctgagcaaa tccgccgcgg aaaaaccgta
    31921 gttgttgaag gttgtgaaga gaaactggca ccactggacc tgattcgtct cggcatgaac
    31981 taagcgtgtg aatgccgccg atggcggcat tgcttttttt acttcacgga atatttcgcc
    32041 actgtcgctt tcgcgccatg cgctaataaa gacaagtacg cttccgtcac tttagtcgta
    32101 aacaagctat tatctggcaa atcatcacca aatatcgcct taatcgccaa caatgactgc
    32161 acgcgcgctg tcccttcagc actactttgt actgccttct gaataacagg taacagtggg
    32221 tcactgattt ctatcggatt tccctgttca tcaacaccac cgacataacg catccaaccc
    32281 gcgacgccca gcgccagcag atcgaacttg ctgtcatgcg ccagatgcca gcgaacagaa
    32341 tccaacatcc gctgtggcaa tttctggctg ccatccatcg caatctgcca ggttcgatga
    32401 cgtaacgccg ggttgctata gcgttcaatt aatcggttag cgtaatcttg caaatcaacg
    32461 ccctgcactt tcagcgtcgg cgcttgttcc tgcaacatta aggtatacgc cgcatgacga
    32521 taatgttcat cctccatgca gtcattaatg tgctgatatc cggcaagata gcccagatac
    32581 gccaggaatg aatgactgcc attgagcatg cgcaacttca tctcttcata aggcagcaca
    32641 tcactaacca gttcgactcc cgctttttcc cattccggac gtccggcaac aaagttatct
    32701 tctattaccc actggcggaa aggttcacag gcaacgcctg ccggatcgcg cacaccggta
    32761 agttgttcga ttttcgccag cgtatcctct gtcactgcgg gcacaatacg gtccaccatt
    32821 gttgatggga aagtcacgtt atcttcgatc cattgtgcca gttttacatc aatggcttgc
    32881 gcataggaag tgacaacgtc acgcataaca tgaccgtttt ctggcatgtt gtcacatgac
    32941 atgacggtaa atgcgggaag tcctgccgct ttacggcgag ccagcgcctc aacaatcacc
    33001 cctgttgcag ttttcggctg gtggggattt tgcacgtcgg caacgaccat cgggtgatcg
    33061 agcattaact gtccggtcgc cggagagtgg aaataccctt tttcggtgat tgtcagagag
    33121 acaatcgcga tttgcggttc acacatcgca gccaacacgg tttctaagcc gtctatttgt
    33181 acgtgtaagg cttttttaac gacgccaacg acgcgagccg tccacgcatc agccgacatt
    33241 tccgcaacgg tataaagatt atcttgctgt tgtaaatcgg caatttgctg ttcgccgccg
    33301 attaagttga cctcataata tccccagtca ctgaaatgtt ccgtagcaag aatatcggca
    33361 tacacgccct gatgcgcacg gtgaaatgca ccaaagccta aatgaacaat tcttggggcc
    33421 aggttattac gatcataaac agggagcgtc gcttttgctg ata
//
LOCUS       DAPOXO010000056        33182 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPOXO010000056 DAPOXO010000000
VERSION     DAPOXO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33182
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.056"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..604)
                     /locus_tag="ROH59_003079"
     CDS             complement(<1..604)
                     /locus_tag="ROH59_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDX4805528.1"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSSGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREEST
                     WILQNSQACLLVTSAQFYPMYQQIQQEDASQLRHICLTDMALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFA"
     gene            complement(677..1894)
                     /gene="caiB"
                     /locus_tag="ROH59_003080"
     CDS             complement(677..1894)
                     /gene="caiB"
                     /locus_tag="ROH59_003080"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HDX4805529.1"
                     /translation="MDHLTMPKFGPLSGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIAECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            complement(2023..3165)
                     /gene="caiA"
                     /locus_tag="ROH59_003081"
     CDS             complement(2023..3165)
                     /gene="caiA"
                     /locus_tag="ROH59_003081"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HDX4805530.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            complement(3196..4710)
                     /gene="caiT"
                     /locus_tag="ROH59_003082"
     CDS             complement(3196..4710)
                     /gene="caiT"
                     /locus_tag="ROH59_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HDX4805531.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKY"
     gene            5183..5953
                     /locus_tag="ROH59_003083"
     CDS             5183..5953
                     /locus_tag="ROH59_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HDX4805532.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     VLAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     gene            5968..6909
                     /locus_tag="ROH59_003084"
     CDS             5968..6909
                     /locus_tag="ROH59_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDX4805533.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQA
                     IQLGANHVWKLSGKPDERMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LNAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            6960..8246
                     /locus_tag="ROH59_003085"
     CDS             6960..8246
                     /locus_tag="ROH59_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDX4805534.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFNGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            8243..8530
                     /gene="fixX"
                     /locus_tag="ROH59_003086"
     CDS             8243..8530
                     /gene="fixX"
                     /locus_tag="ROH59_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HDX4805535.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKRDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     gene            8589..9920
                     /locus_tag="ROH59_003087"
     CDS             8589..9920
                     /locus_tag="ROH59_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4805536.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFEEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWTLPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     gene            10028..10558
                     /gene="kefF"
                     /locus_tag="ROH59_003088"
     CDS             10028..10558
                     /gene="kefF"
                     /locus_tag="ROH59_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HDX4805537.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            10551..12413
                     /gene="kefC"
                     /locus_tag="ROH59_003089"
     CDS             10551..12413
                     /gene="kefC"
                     /locus_tag="ROH59_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HDX4805538.1"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRRAFAVLLFQDIAAI
                     PLVAMIPLLAASSASTTMGAFVLSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            12605..13084
                     /gene="folA"
                     /locus_tag="ROH59_003090"
     CDS             12605..13084
                     /gene="folA"
                     /locus_tag="ROH59_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HDX4805539.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            13170..13403
                     /locus_tag="ROH59_003091"
     CDS             13170..13403
                     /locus_tag="ROH59_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="HDX4805540.1"
                     /translation="MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKH
                     AATRWREENAEAIAALNQLADETGCFSDEYRSF"
     gene            13406..13690
                     /locus_tag="ROH59_003092"
     CDS             13406..13690
                     /locus_tag="ROH59_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="HDX4805541.1"
                     /translation="MQFTVYRSRGRNAAFPFVIDVTSDIIGEINRRIVIPLTPIERFS
                     RIRPPERLNPILLLIDGKEYVLMTHETATVPVNALGTKFCDASAHRTLIK"
     gene            complement(13717..14565)
                     /gene="apaH"
                     /locus_tag="ROH59_003093"
     CDS             complement(13717..14565)
                     /gene="apaH"
                     /locus_tag="ROH59_003093"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HDX4805542.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYNIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLSE
                     GEAVAS"
     gene            complement(14572..14949)
                     /gene="apaG"
                     /locus_tag="ROH59_003094"
     CDS             complement(14572..14949)
                     /gene="apaG"
                     /locus_tag="ROH59_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HDX4805543.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            complement(14952..15773)
                     /gene="rsmA"
                     /locus_tag="ROH59_003095"
     CDS             complement(14952..15773)
                     /gene="rsmA"
                     /locus_tag="ROH59_003095"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDX4805544.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAA
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVGVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            complement(15770..16759)
                     /gene="pdxA"
                     /locus_tag="ROH59_003096"
     CDS             complement(15770..16759)
                     /gene="pdxA"
                     /locus_tag="ROH59_003096"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HDX4805545.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLIVQLAQREWPVELVVCADATLLT
                     DRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRESVTVGLLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLDELREQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     gene            complement(16759..18045)
                     /gene="surA"
                     /locus_tag="ROH59_003097"
     CDS             complement(16759..18045)
                     /gene="surA"
                     /locus_tag="ROH59_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HDX4805546.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            complement(18098..20452)
                     /gene="lptD"
                     /locus_tag="ROH59_003098"
     CDS             complement(18098..20452)
                     /gene="lptD"
                     /locus_tag="ROH59_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HDX4805547.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTRLAESANRVMPQFKVDGRMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSKIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISDRWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            20707..21522
                     /gene="djlA"
                     /locus_tag="ROH59_003099"
     CDS             20707..21522
                     /gene="djlA"
                     /locus_tag="ROH59_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HDX4805548.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQSGSGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            complement(21672..22331)
                     /gene="rluA"
                     /locus_tag="ROH59_003100"
     CDS             complement(21672..22331)
                     /gene="rluA"
                     /locus_tag="ROH59_003100"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HDX4805549.1"
                     /translation="MGMENYNPPQEPWLVVLYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     gene            complement(22343..25249)
                     /gene="rapA"
                     /locus_tag="ROH59_003101"
     CDS             complement(22343..25249)
                     /gene="rapA"
                     /locus_tag="ROH59_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HDX4805550.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDETEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            complement(25414..27765)
                     /gene="polB"
                     /locus_tag="ROH59_003102"
     CDS             complement(25414..27765)
                     /gene="polB"
                     /locus_tag="ROH59_003102"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HDX4805551.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVFLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMRNGAIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPLLLEKLNAWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQVKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKTLIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENHKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            complement(27840..28535)
                     /gene="araD"
                     /locus_tag="ROH59_003103"
     CDS             complement(27840..28535)
                     /gene="araD"
                     /locus_tag="ROH59_003103"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDX4805552.1"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRGRGVFVIKPS
                     GVDYSIMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGPIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            complement(28650..30152)
                     /gene="araA"
                     /locus_tag="ROH59_003104"
     CDS             complement(28650..30152)
                     /gene="araA"
                     /locus_tag="ROH59_003104"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDX4805553.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     gene            complement(30163..31863)
                     /gene="araB"
                     /locus_tag="ROH59_003105"
     CDS             complement(30163..31863)
                     /gene="araB"
                     /locus_tag="ROH59_003105"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HDX4805554.1"
                     /translation="MAIAIGLDFGSDSVRALAVECATGEEIATSVEWYPRWQNGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELCVEQRAAVVGIGVDTTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHTPGNVDYSRNIGGIYSSEWFWAKI
                     LHVTRQDNAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQINASQKQLLPALTEVWAQNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
                     "
     gene            32202..33047
                     /gene="araC"
                     /locus_tag="ROH59_003106"
     CDS             32202..33047
                     /gene="araC"
                     /locus_tag="ROH59_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HDX4805555.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGIVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAHEWYHQWVYFRPRA
                     YWHEWVNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCE"
BASE COUNT         7501 a         8661 c         9031 g         7989 t
ORIGIN      
        1 cagcgaagcg caggttgtaa tgagttatca ccaccccttt cggtcgggag gtggtgccgg
       61 aggtgaagag aatttccgcc gtatcgtcag tcgatagcgg cggtgcatag cacaaggtgg
      121 caggttgttg atttttcagt tgagtaaacg aactcacgcc atcatcagcg ggaagtgcca
      181 tatctgtcag gcaaatgtgc cgcaactgag aggcatcttc ctgctgaatc tgttgataca
      241 taggataaaa ttgcgcactg gtcaccagca ggcacgcctg gctattttgc aggatccacg
      301 tgctttcttc gcgcaacagg cgggcgttaa tcggcaccat aatcgcgcca atttttgcca
      361 acccgaacca gcaaaagata aattccgggc agttgtcgag atgtagagca accttgtcgc
      421 ctttgcgaat ccccagcgta taaaacaggt ttgccgtgcg gttaatctcc tgatttaact
      481 caagataact ataccggtta acgactccgc tgctggattc acaaatcagc gccgttttat
      541 gaccgtaaac gtccgccaga tcgtcccaca tttgacgtag atgttgtccg ccaatgatat
      601 ccattgcacc tctatccatt ttgttcgttt gttattgagc gggcactagt caggcaagct
      661 gactgacgcc acgcgtttag tcctcaactt tggccagacc tttgctgacc aactcctgaa
      721 tgtcgttttc gctgtagccg atatttttca aaatggcagc cgtgtccatg ccatgtgagg
      781 gcattccgcg ccagatttgt ccggggttat ttttgaattt cggcatgata ttcggccctt
      841 tgcaggtgcg accatccatc gtttgccact gagtgattga ttcgcgagcc acatactgtg
      901 gattgctttc cagttccggt acggtcagta ctttggcaca ggcgatattc agttcggcaa
      961 agcgttcttt aacttctgcg atggtatgtg ccgccagcca ggcatcgagt ttctcttcta
     1021 ccagtgggcc gtaagggcat tcgatacggt ggataagctg ggtgccttcc ggaatttctg
     1081 gcgtgccgag cagatgtgcg aggccaatat ctttaaagca ctctgcaatt tgagtaatgc
     1141 ccaccagttc catcacgatg tagccgtcgg cgcatttata cagaccgcaa ccggcgtagt
     1201 agggatcttt ccctttggtc atgcgcgggc acatttcgcc gccgttgaag taatccatca
     1261 tgaagtactg gcccatacgc agcatcactt catacatggc gatgtcgatg ctttcgcctt
     1321 tgccggtttc acgcacttta tgcagtgctg ccagcgccgc cgtggtggca gtcaggccag
     1381 aaaagtaatc ggcggtatac gggaaggcag gcattggctg gtcaacatca ccgttctgaa
     1441 tcaggtaacc actgaaggcc tgggcgatag tgttataggc cggaagattg gtgtactcct
     1501 cggtgccata ctgaccaaaa ccggacaggt gagcgataac cagttttggg ttgtgctgcc
     1561 acaggacttc atcggtaatg ccacgacggg caaaggccgg acctttactg gcttcgatga
     1621 agatatcggt ggtttccatt aatttcagaa acgcttcacg accttcatct ttgaagatat
     1681 ttaacgacag cgcgtgcagg ttgcggcggg aaagttgcgg gtagttcggt tgaacgcgaa
     1741 tggtgtcggc ccaggcgacg ttttcgatcc agataacttc cgcgccccat tctgcgaaca
     1801 tttgtccggc aaacggtccg gcgatttcga taccggagaa gacaacgcgc aatccggaca
     1861 gcggcccgaa tttcggcatg gttagatgat ccattattag ctcctgaaaa atttatgtag
     1921 cgcatgactg ccggatgcgg cgtaaacgcc ttatccggcc gacattcgtg ctcctgtagg
     1981 cctgataaga cgcgtcagcg tcgcatcagg cagcgcacgg acttagcggt attgcttcag
     2041 caccgcgcgg cccagcgtca ggatctgcat ttcgtcagat cctccggaaa cgcggtctac
     2101 acgcaggtca cgccagaagc ggctgatgcg gtgattaccc gcaatcccga caccgcccag
     2161 cacctgcatt gcgctatcca ccacttcaaa tgccgcattg gcgcagaagt atttgcacat
     2221 cgctgcatcg ccagaggtga tggtgccgtt gtctgctttc cacgctgctt catacagcat
     2281 gtttttcatg gagtttaatt tgatcgccat gtgggcgaat ttttcctgaa tcaactggaa
     2341 acgaccaata gcctcgccaa actgcacgcg ctggttggcg tagcgcgccg catcttcaaa
     2401 ggcgcacatc gccgtaccgt agttggtcag ggctaccagg aaacgttcat ggtcgaactc
     2461 ttctttgacg cggttaaagc cgttaccttc ccgaccgaac atgtctttct cgtccagttc
     2521 cacatcgtca aaggtgattt cacagcagct atccatacgc agaccgagct tctcaagttt
     2581 ggtcactttg atgcccggtt tgctcatatc aacaaaccat tcggtgtaga caggtttgtc
     2641 cggagaagcc ccgtcgcgcg ccatcaccac gatgtacggg gtgtaggcgc tgctggtaat
     2701 aaaacactta ctaccattaa gataaatctt accatttcta cgggtataag tcgttttcag
     2761 gctacccacg tcggagcctg cgcccggttc ggtaatcgct gagttccaca tctgcttacc
     2821 ggtgccgcgg aaagccatga tcttgtcgat ctgctcttgc gtaccttcac gcaggaaggt
     2881 gttaaacccg cccggtaact gatacagcac gtaagttggc gctcccagac gacccagttc
     2941 catccacacg gcggcgagag taacaaaccc cgcgtccaga ccaccgtgct cttcagggat
     3001 cagcagactg tcgataccca tatccgccag ggctttgaca aaacgttccg ggtagacgct
     3061 gtcacggtcg cactcggcaa aataggcctc ccagttttcg ctggccatca gttcgcggat
     3121 accggcgaca aacagttcct gctcatcatt taaattaaaa tccatctttc aacctcttga
     3181 tatttttggg gttaattaat atttccagtt ctgtttcgcg tctttaataa aggagagcgt
     3241 caccatgatg ttgacgaaga acagcgggca tcctccggcg ataatggcgg tttgaatcgg
     3301 tttcaggccg ccgagcgcca gcagaacaat gccgataatg ccaaccagaa ctgaccaacc
     3361 aatgcgcacc agcagcgggg gttcttcgcc gtcacgtact tcgcggcaag tggacatcgc
     3421 cagggtataa gagcaggcgt taaccagcgt aacggtggca ataaagcaga ggatgaagaa
     3481 gccccacatg gtggcggtgc tgagtggcag agcggcccag gtttcgatga tggcgcgcgc
     3541 cacaccgtac tgttcgatca gatttggaat gttgatgatg tttttatcta tcaacagcag
     3601 ggtgttacta ccgagtacag tccacaggat ccaggttgac gctgtcagcc ccagcaccat
     3661 gccgaagcac agttcacgca cggtacgacc acgggagatg cgggcgagga agatactcat
     3721 ctggatagcg taaatcaccc accatgccca gtagaacacg gtccagccct gcgggaagcc
     3781 gcctttagcg atgggatcgg tatagaacaa catgcgcggc agatacatca gcaacatccc
     3841 caccgaatcg gtgaagtagt tcatgatgaa gctggcaccg ctgacgatga acacccaacc
     3901 cagcatcagg aagctcaggt aactacgcac gtcactggcg atacgtaccc ctttttgcag
     3961 accgcaagcg acgcaaatgg cgttgaggat aatccagcag gtaatgatga tagcgtccag
     4021 ttgcagggta tgcggaatgc caaacaacca ttgcatacac tcggttacca gcggcgtggc
     4081 aaggcccaga ctggtaccca tcgcgaagat caaggcgacg agatagaagt tgtcgacgat
     4141 agtgccgaac aaccctttgg cgtgtttttc acctaccagc ggcaccaggg tcgagctggg
     4201 gcgaatcact tccattttgc ggacaaagaa gaagtaagcg aaggcgactg aaaggaagct
     4261 gtaagtggcc cacggcagag gtccccagtg gaacaagctg taagccagcc ccaactcttt
     4321 cgcgcctgtt gagttcggtt ctaagccaaa cggcggggtg gagatgtagt agtagatctc
     4381 aatcgatccc cagaacagta cggcagcaga cgtacaggag gcgaacatca taaagatcca
     4441 actggcggta ctaaattctg gtggttcgtt acctaaacgc tttttggcat acgggccaaa
     4501 caccagccag aaccagccga aaagcatcac caccatatac cattcaaatg cccatcccca
     4561 tacattggtg acgtaactga atacagcatt aataacgaca ttcgctgcat ccagatctct
     4621 gactgtaagc caacaaagta tgccgacgat tattaacggc ggaaagaaaa ccttcggttc
     4681 tattcccgtt tttctctttt cattcttcat gagttaattc cactgtgaaa acgaatattt
     4741 attttgcgtt cccgtttgtt ttatttttgt taacatttaa tataattatt attaacctcg
     4801 tggacgcgtt aatggctaac tcataatggg tattcaataa gctgcattct gtgattgttg
     4861 tcacattttt gtttcgggtg aatagagggc atttttttgt taattttgat tattaatcag
     4921 tttgttatgt tctgttgtgg gtaaaaaaat agcatctgac tttcaatatt ggtgatccat
     4981 aaaacaatat tgaaaatttc tttttgctac gccatgtttt caatattggt gaggagctta
     5041 acaatattga aagttggatt tatctgcgtg tgacattttc aatattggtg attaaagttt
     5101 tatttccaaa ttaaagggcg tgatatctgt aattaacacc accgatatga acgacgtttc
     5161 cttcatgatt tctggagatg caatgaagat tattacttgc tataagtgcg tgcctgatga
     5221 acaggatatt gcggtcaata atgctgatgg ttcgttagac ttcagcaaag ccgatgccaa
     5281 aataagccaa tacgatctca acgctattga agcggcttgc cagctaaagc aacaggcagc
     5341 agaggcgcag gtgacggcct taagtgtggg cggtaaagcc ctgaccaacg ccaaagggcg
     5401 taaagatgtg ctatcgcgcg gtccggatga actgattgtg gtgattgatg accagttcga
     5461 gcaggcactg ccgcaacaaa cggcgagcgt acttgctgca gccgctcaga aagcaggctt
     5521 tgatttgatc ctctgtggcg atggttcttc cgacctttat gcccagcagg ttggtttgct
     5581 ggtaggcgaa atccttaata ttccggcagt taacggcgtc agcaaaatta tctccctgac
     5641 ggcagatacc ctcaccgttg agcgcgaact ggaagatgaa acagaaacct taagcattcc
     5701 gctgcctgcg gttgttgctg tttccactga tatcaactcc ccacaaattc cttcgatgaa
     5761 agccattctc ggcgcggcga aaaagccagt ccaggtatgg tcggcggcgg atatcggttt
     5821 taacgcagag gcagcctggt cagaacaaca ggttgccgcg ccgaaacagc gcgagcgtca
     5881 gcgcatcgtg attgaaggcg acggcgaaga acagatcgcc gcatttgctg aaaatcttcg
     5941 caaagtcatt taattacagg ggatgctatg aacacgtttt ctcaagtctg ggtattcagc
     6001 gatacccctt ctcgtctgcc ggaactgatg aacggtgcgc aggctttagc taatcaaatc
     6061 aacacgttcg tcctcaatga tgccgacggc gcacaggcaa tccagctcgg cgctaatcat
     6121 gtctggaaat taagcggcaa accagacgag cggatgatcg aagattacgc cggtgtcatg
     6181 gctgacacta ttcgccagca cggcgcagac ggtctggtgc tgttgccaaa cacccgtcgc
     6241 ggcaaattac tggcggcgaa actgggttac cgccttaacg cggcggtgtc taacgatgcc
     6301 agcgctgtta gcgtgcagga cggtaaagcg acagtgaaac acatggttta cggcggtctg
     6361 gcgattggcg aagaacgcat tgccacgccg tatgcggtac tgaccatcag cagcggcacg
     6421 ttcgatgcgg ctcagccaga cgcgtcacgc actggcgaaa cgcacaccgt ggagtggcag
     6481 gctccggctg tggcgattac ccgcacggca acccaggcgc gtcagagcaa cagcgtcgat
     6541 ctcgacaaag cccgcctggt ggtcagcgtc ggtcgcggta ttggcagcaa agagaacatt
     6601 gcgctggcag aacagctttg taaggcgata ggtgcggagt tggcctgttc tcgtccggtg
     6661 gcggaaaacg aaaaatggat ggagcacgaa cgctatgtcg gtatctccaa cctgatgctg
     6721 aaacctgaat tgtacctggc ggtggggatc tccgggcaga tccagcacat ggttggcgct
     6781 aatgcgtcgc aaaccatttt cgccatcaac aaagataaaa atgcgccgat cttccagtac
     6841 gcggattacg gcattgttgg cgacgccgtg aagatccttc cggcactgac cgcagcttta
     6901 gcgcgttgat ccactctggc agggctgcat tccggccctg ccgctgacag ggagctctta
     6961 tgtccgaaga tatctttgac gccatcatcg tcggtgcagg gcttgccggt tcggttgccg
     7021 cactggtgct cgcccgcgaa ggtgcgcaag tgttagttat cgagcgaggc aattccgcag
     7081 gtgccaagaa cgtcactggc gggcgtctct atgcccacag tctggaacac attattcctg
     7141 gtttcgctga ctccgccccc gtagaacgcc tgatcaccca tgaaaaactt gcgtttatga
     7201 cggaaaagtc agcgatgact atggactact gcaatggcga cgaaacctct ccatcccagc
     7261 gttcttactc cgttttgcgc agtaaatttg atgcctggct gatggagcag gccgaagaag
     7321 cgggcgcgca gttaattacc gggatccgcg tcgataacct cgtacagcgc gatggcaaag
     7381 tcgtcggtgt agaagccgat ggcgatgtga ttgaagcgaa aacggtgatc cttgctgatg
     7441 gggtgaattc catccttgcc gaaaagctgg ggatggcaaa acgcgttaaa ccgacggatg
     7501 tggcggttgg cgtgaaggaa ctgatcgagt taccgaagtc ggttattgaa gaccgttttc
     7561 agttgcaggg taatcagggc gcggcttgcc tgtttgcggg atcacccacc gatggcctga
     7621 tgggcggtgg cttcctttat accaatgaaa ataccctgtc gctggggctg gtttgtggtc
     7681 tccatcatct gcatgacgca aaaaaatcgg tgccgcaaat gctggaagat ttcaaacaac
     7741 atccggccgt tgcaccgctg atcgcgggcg gcaagctggt ggaatattcc gctcacgtag
     7801 tgccggaagc aggcatcaac atgctgccgg agctggtcgg tgacggcgta ttgattgccg
     7861 gtgatgctgc cggaatgtgt atgaacctcg gttttaccat tcgcggtatg gatctggcga
     7921 ttgccgccgg ggaagcagca gcaaaaactg tgctttcagc gatgaaaagc gacgatttca
     7981 gtaagcaaaa actcgcggaa tatcgtcagc atcttgagag tggcccgctg cgcgatatgc
     8041 gcatgtacca gaaactaccg gcgttccttg ataacccacg catgtttaac ggctacccgg
     8101 aactggcggt gggcgtggcg cgtgacctgt tcaccattga cggcagtgcg ccggaactga
     8161 tgcgcaagaa aatcctccgc cacggcaaga aagtgggctt catcaatctg atcaaggatg
     8221 gcatgaaagg agtgaccgtt ttatgacttc tcccgtcaat gtggacgtca aactgggcgt
     8281 caataaattc aatgtcgatg aagagcatcc gcacattgtt gtgaaggccg atgccgataa
     8341 acaggccctg gagctgctgg tgaaagcgtg ccccgcaggt ctgtacaaga agcgggatga
     8401 cggcagtgtg cgcttcgatt acgccggatg tctggagtgc ggcacctgtc gcattctggg
     8461 gctggggtcg gcgctggaac agtgggaata cccgcgcggc acctttggtg tggagttccg
     8521 ttacggctga tgttggtttg atacgtaatg ccgtactgac tctcattgca aaaaaacagg
     8581 aataacccat gcaaccgtcc agaaactttg atgatcttaa attctcctct attcaccgcc
     8641 gcattttgct gtggggaagc ggtggtccgt ttctggatgg ttatgtactg gtaatgattg
     8701 gcgtggcgct ggagcaactg actccggcgc tgaaactgga cgctgactgg attggcttgc
     8761 tgggcgcggg aacgctcgcc gggctgttcg ttggcacatc gctgtttggc tatatctccg
     8821 ataaagtcgg acggcgcaaa atgttcctca ttgatatcat cgccatcggc gtgatatcgg
     8881 tggcaacgat gtttgtctca tcccccgtcg aactgttggt gatgcgggta cttatcggca
     8941 ttgtcattgg tgcggattat cccatcgcca cctcaatgat caccgagttc tccagtaccc
     9001 gtcagcgggc gttttccatc agctttattg ccgcgatgtg gtatgtcggc gcgacctgcg
     9061 ccgatttggt cggctattgg ctttatgatg tggaaggcgg ctggcgctgg atgctgggta
     9121 gcgcagcgat tccctgtttg ttgattttga ttggtcgatt cgaactgcct gaatctcccc
     9181 gctggttgtt acgcaaaggg cgagtaaaag agtgcgaaga gatgatgata aaactgtttg
     9241 gcgaaccggt ggctttcgag gaagagcagc cgcagcaaac ccgttttcgc gatctgttta
     9301 atcgccgcca ttttcctttt gttctgtttg ttgccgctat ctggacctgc caggtgatcc
     9361 ccatgttcgc catttacacc tttggcccgc aaatcgttgg tttgttggga ttgggggttg
     9421 gcaaaaacgc ggcactgggg aacgtggtga ttagcctgtt ctttatgctc ggctgtattc
     9481 cgccgatgct gtggctaaac actgccggac ggcgtccatt gttgattggc agctttgcca
     9541 tgatgacgct ggcgctggcg gttttggggc tgatcccgga tatggggatc tggctggtag
     9601 tgatggcctt tgcggtgtat gcctttttct ctggcgggcc gggtaatttg cagtggctct
     9661 atcctaatga actcttcccg acggatatcc gcgcctctgc cgtgggcgtg attatgtcct
     9721 taagccgtat tggcactatt gtatcgacct ggacactgcc gatctttatc aataattacg
     9781 gtatcagtaa cacgatgcta atgggggcgg gtatctcgct atttggcttg ttgatttccg
     9841 tagcgtttgc cccggagact cgagggatgt cactggcgca gaccagcaat atgacgatcc
     9901 gcgggcagag aatggggtaa tttgttcaga tttctctctt ttctgaatca atattattga
     9961 ctataagctg cgtgaatata tgactacact ttgtgggaaa acaaaggcgt aatcacgcgg
    10021 gctacctatg attcttataa tttatgcgca tccatatccg catcattccc atgcgaataa
    10081 acggatgctt gaacaggcaa ggacgctgga aggcgtcgaa attcgctctc tttatcaact
    10141 ctatcctgac ttcaatatcg acattgccgc cgaacaggag gcgctgtctc gtgccgatct
    10201 gatcgtctgg cagcacccga tgcagtggta cagcattcca ccgcttctta aactttggat
    10261 cgataaagtt ttctcgcacg gctgggctta cggtcacggc ggcacggcgc tgcacggcaa
    10321 acatttgctg tgggcggtga cgaccggcgg cggggaaagc cattttgaga ttggtgcgca
    10381 tccgggcttt gatgtgctgt cgcagccgct acaggcgacg gcaatctact gcgggctgaa
    10441 ctggctgcca ccgtttgcca tgcactgcac ctttatttgt gacgacgaaa ccctcgaagg
    10501 gcaggcgcgg cactataagc aacgtctgct ggaatggcag gaggcacatc atggatagcc
    10561 atacgcttat tcaggcgctg atttatctcg gttcggcggc gctgattgtt cccattgcgg
    10621 tacgtctcgg tctgggatcg gttcttggct acctgatcgc cggctgcatt attggcccgt
    10681 gggggctgcg actggtgacc gatgccgaat ctattctgca ctttgcagag attggcgtgg
    10741 tgctgatgct gtttattatc ggcctcgaac tcgatccaca aaggctgtgg aagctgcgtg
    10801 cggcagtgtt cggcggtggc gcattgcaga tggtgatttg cggcggcctg ctggggctgt
    10861 tttgtatgtt acttgggctg cgctggcagg tcgcagaatt gatcggcatg acgctggcgc
    10921 tctcatcaac ggcgattgcc atgcaggcga tgaatgaacg caatctgatg gtgacgcaaa
    10981 tgggccgcag agcctttgcg gtgctgctgt tccaggatat cgcggcgatc ccactggtgg
    11041 cgatgatccc gctactggca gcgagtagtg cctcgacgac gatgggcgca tttgttctct
    11101 cggcgttaaa agtggcgggc gcgctggtgc tggtggtatt gctggggcgc tatgtcacgc
    11161 gtccggcact gcgttttgtt gcccgctctg gcttgcggga agtgtttagt gccgtggcgt
    11221 tattcctcgt gtttggcttt ggtttgctgc tggaagaggt cggcttgtcg atggcgatgg
    11281 gcgcgtttct ggcgggcgta ctgctggcaa gctcggaata ccgtcatgcg ctggaaagcg
    11341 atatcgaacc atttaaaggt ttgctgctgg ggctgttttt catcggcgtt ggcatgtcga
    11401 tagactttgg cacgctgctt gaaaatccgt tgcgcattgt cattttgctg ctcggtttcc
    11461 tcatcatcaa aatcgccatg ctgtggctga ttgcccggcc gttgcaggtg ccaaataaac
    11521 agcgtcgctg gtttgcggtg ctgttagggc agggcagtga gtttgccttt gtagtatttg
    11581 gtgcggcgca gatggcgaat gtgctggagc cagagtgggc gaaatcgctg accctggcgg
    11641 tggcactgtc gatggcggca acgccgattc tgctggtgat cctcaatcgc cttgagcaat
    11701 cttctactga agaggcgcgt gaagccgatg agatcgacga agaacagccg cgggtaatca
    11761 ttgccggatt cggtcgtttt gggcagataa ccggacgttt actgctctcc agcggggtga
    11821 aaatggtggt gctcgatcac gacccggacc atatcgaaac gctgcgtaaa ttcggtatga
    11881 aagtgtttta tggcgatgcc acgcggatgg atttactgga atctgccgga gcggcgaaag
    11941 cggaagtgct gattaacgcc atcgacgatc cgcaaaccaa cctgcaactg acggagatgg
    12001 tgaaagaaca tttcccacat ttgcagatta ttgcccgcgc ccgcgatgtc gaccactaca
    12061 ttcgtttgcg tcaggcaggc gttgaaaagc cggagcgtga aaccttcgaa ggtgcgctga
    12121 aaaccgggcg tctggcactg gaaagtttag gtctggggcc gtatgaagcg cgagaacgtg
    12181 ccgatgtgtt ccgccgcttt aatattcaga tggtggaaga gatggcaatg gttgagaacg
    12241 acaccaaagc ccgtgcggcg gtctataaac gcaccagcgc gatgttaagt gagatcatta
    12301 ccgaagaccg tgaacatctg tcattaattc aacgacatgg ctggcaggga accgaagaag
    12361 ggaaacatac tggcaatatg gcggatgaac cggaaacgaa gccctcatcc taataaagag
    12421 tgacgtaaat cacgctttac agctaactgt ttgtttttgt ttcattgtaa tgcggcgagt
    12481 ccagggagag agcgtggact cgccagcaga atataaaatt ttcctcaaca tcatcctcgc
    12541 accagtcgac gacggtttac gctttacgta tagtggcgac aatttttttt atcgggaaat
    12601 ctcaatgatc agtctgattg cggcgttagc ggtagatcgc gttatcggca tggaaaacgc
    12661 catgccgtgg aacctgcctg ccgatctcgc ctggtttaaa cgcaacactt taaataaacc
    12721 cgtgattatg ggccgccata cctgggaatc catcggtcgt ccgttgccag gacgcaaaaa
    12781 tattatcctc agcagtcaac cgggtacgga cgatcgcgta acgtgggtga agtcggtgga
    12841 tgaagccatt gcggcgtgtg gtgacgtacc agaaatcatg gtgattggcg gcggtcgcgt
    12901 ttatgagcag ttcctgccga aagcgcaaaa actgtatctg acgcatatcg acgcggaagt
    12961 ggaaggcgac acccatttcc cggattacga gccggatgac tgggaatcgg tattcagtga
    13021 attccacgac gccgatgcgc agaactctca cagctattgc tttgagattc tggagcggcg
    13081 gtaatttcgt atattagaat tccggcatca ctgatacgtg cagatatccg tgtatactag
    13141 acgtataaat tgtacaggag cacgagatca tgactgcaaa acgtaccaca caaagtgtga
    13201 ccgtcaccgt cgaccgtgag ttagtcaatc gcgctcgtga tgcaggctta aatatgagcg
    13261 ccacccttac ggttgcgctc aatgctgaac ttaaaaaaca tgcagcaaca cgttggcgtg
    13321 aagagaacgc agaagctatc gctgcgttaa atcaattggc tgatgaaacc ggatgtttct
    13381 ctgatgagta ccggagcttc tagcgatgca atttacggta taccgcagtc gcggcaggaa
    13441 cgccgcgttt ccctttgtta ttgatgttac cagcgacatt attggtgaga ttaatcgccg
    13501 tatcgttatt ccattaacac ctattgaacg atttagccgt attcgcccac cagaacggct
    13561 taacccaatc cttttactga tagacggcaa agaatatgtg ctcatgacgc atgagactgc
    13621 aactgttcca gttaacgcgc tgggaacgaa attttgcgat gccagcgcgc accgaacgtt
    13681 gattaaatga gcattagatt ttatgctcga cgggatttaa gacgctaccg cctctccctc
    13741 actcaaatcc ttatgccggt tcgacggctg gacaaaatac tgtttatctt cccagcgcag
    13801 gcaggttaat gtaccacccc agcagcagcc ggtatccagc gcgtaaatac cttccggcgt
    13861 acctttgcct tccagcgatg cccagtgacc aaaggcgatg ttgtactctt cagcgacggg
    13921 gccaggaatc gcaaaccacg gtttcagtgg ggcaggggcc tcttccggcg attctttgct
    13981 gtacatatcc agttgaccgt tcgggaagca aaaacgcata cgggtaaagg cgttggtgat
    14041 aaaacgcagt cttcccagcc cccgcaattc cggtgaccag ttatttggca tatcgccgta
    14101 catggcatca aggaagaagg gataggagtc actcgacagc accgcttcta catcgcgcgc
    14161 gcactctttg gcggtctgca gatcccactg cggcgtgatc ccggcgtggg ccatcaccaa
    14221 ctttttctct tcgtcgattt gcagcaaagg ctggcgacgc agccagttaa gcagctcgtc
    14281 ggcatccggc gcttccagca gcggtgtcag gcgatctttc ggtttattgc ggctgatccc
    14341 ggcaaatacc gccagcagat gcagatcgtg attacccagc accagacgta cgctgtcgcc
    14401 taaggatttc acatagcgca gaacatccag cgaacccggg ccgcgcgcga ccagatcgcc
    14461 cgtcagccag agggtatctt tcccaggggt aaattctact ttatgcagca atgcgatcag
    14521 ttcatcgtaa caaccatgaa cgtcgccaat aaggtatgtc gccatattct tttaatgaat
    14581 gagtgtggga acggcgagtc ggaatacggg aatgtcgatg ctgaaaggga cgccattttc
    14641 atcgatcatt tcgtagtgac cctgcatggt gcccagcggg gtttcaatga ttgcaccgct
    14701 ggtgtactgg tactcttcgc caggcgcgat aagtggctgg acgccaacca ctccttcgcc
    14761 ctggacttcg gtttcacggc cattgccatt ggtgatcagc cagtaacgcc ccaacaactg
    14821 cactggcgct cgccccagat tgcgtatggt tacggtataa gcaaaaacgt aacgttcatt
    14881 atcaggtgaa gattgggcct caatgtagac gctttgaacc tgaatacaca ctcggggcga
    14941 attgatcatc gttaactctc ctgcaaaggc gcgttctccg ccagatagtt cgccatctgg
    15001 caatattgcg cgacagagat attttccgct cgcatcgccg ggtcgatccc cattcccgtt
    15061 aacaccccga cgctaaacag gttgccgagg ctgttacgaa tggttttacg acgctggtta
    15121 aaggcttcgg tggtgatgcg gctcaacacg cgaacatctt taaccgggtg aggcatcgtt
    15181 gcatgaggaa ccaggcgcac gacggcggaa tccactttgg gtggtggtgt aaaggctgac
    15241 ggcggtactt ccagcaccgg gatcacgttg caatagtatt gcgccatgac gcttaatcga
    15301 ccatacgcct tgctgttcgg tcctgcaacc agacgattca ccacttcttt ttgcaacata
    15361 aagtgcatgt cggcaatggc atcagtatag ctaaacagat ggaacatcaa cggcgtggag
    15421 atgttataag gcaggttgcc gaaaacacgc agcggctggc ccattttcgc ggccagttca
    15481 ccaaagttaa aggtcatcgc atcctgctga taaatcgtca gtttcgggcc taagaatgga
    15541 tgcgtttgca gacgtgccgc cagatcgcgg tcaagttcga tgaccgtcag ctggtccaga
    15601 cgttcgccga ccggttcggt caatgccgcc agaccggggc cgatttcgac catcgcctgg
    15661 cccttctgcg ggttaatggc agaaacaatg ctgtcgatca cgaactgatc gttgagaaag
    15721 ttttgcccga agcgtttacg ggctaagtgg ccctggtgga ctcgattatt cattgggtgt
    15781 taacaatcat tttgatggcg agattaagcg ccgtaataaa actgccgaca tcggctttac
    15841 cacgtcccgc cagttcaagc gcggtgccgt ggtccactga tgtgcgaata aagggcaggc
    15901 ccagcgtaat gttcacaccg cgcccgaagc cctggtattt tagcacggga agaccctgat
    15961 cgtggtacat cgccagcacg gcgtcggcgt tatcgagata tttcggctga aacagggtat
    16021 cggcaggcag cggcccgttg agtttcatcc cctgttcccg cagctcgtcg agtaccggaa
    16081 taatggtgtc tatctcttcc gtacccatat gaccgccttc gcccgcgtgc ggattcagcc
    16141 cgcagaccag aatgcgcggt tcggcaatac caaatttggt ccgcaaatcg tgatgcaaaa
    16201 tagcaatcac ttcgtgcaaa agggcagggg tgatagcatc tgcgatatcg cgcagcggta
    16261 aatgcgtcgt tgccagcgcc acgcgaagtt cttcggtcgc cagcatcatc accacttttt
    16321 tcgcctgcga acgctcttcg aaaaactcgg tatgaccggt aaacggaatg cctgcgtcgt
    16381 taatgacgcc tttatgcacg gggcctgtga tcagcgcagc aaattcaccg ttcagacagc
    16441 catcacacgc tcgcgccagc gtttccacca catagtgccc attttcaacc gctaacagcc
    16501 ccacagtgac agattcacgt agcgcgacag gaagtagcgt taatgtgccc gcagtttgcg
    16561 gttgtgcagg ggagttgggg gaataagggc ggagggtgag cggcaaaccg agcatcgctg
    16621 cccggtcggt aaggagagtg gcatcggcac aaacaaccag ttcgaccggc cactcacgct
    16681 gtgcaagctg gacaattaag tccgggccaa tcccggcggg ctcgccggga gtgatcacaa
    16741 cacgttgggt tttaaccatt agttgctcag gattttaacg taggcgctgg cacgttgttc
    16801 ctgcatccag cttgctgctt cttccgagaa cttacggttc atcagcatgc ggtatgcacg
    16861 atctttctgt gccgcgtcgg ttttatcgac attacgggta tccagcagtt cgattaaatg
    16921 ccagccgaat gaagagtgaa ccggtgcact catttgacct ttgttcaggc gggtcagggc
    16981 gtcacggaag gccggatcga aaatatctgg tgtagcccag ccgagatcac cgccctggtt
    17041 agcagagcct ggatcctgag agaactcttt cgctgcggca gcaaaagtcg ttttaccact
    17101 cttgatatcg gcagcaatct gttccagttt cacgcgggcc tgttcgtcag tcatgatcgg
    17161 cgacggtttc agcagaatat ggcgagcatg aacttcggtc accgagatat ttttgctttc
    17221 gccgcgcagg tcgttaactt tcagaatatg gaagccaacg ccggaacgaa tcgggccaac
    17281 aatgtcgcct ttcttcgcgg tgcttaatgc ctgggcgaag atccccggca actcctgaat
    17341 acggccccag cccatctggc cgccgttcag cgcctgctgg tcggcagaat gagcaatcgc
    17401 cagcttaccg aaatcagcgc cgttacgcgc ctgatcgaca atcgcgcgcg cctggctttc
    17461 cgcttcgttc acctgatcag aggtcgggtt ttccggcagc gggatcagga tgtggctcag
    17521 gttcagctca gtgctggcgt cgttttggtt acccacttgc tgcgccaggg attcgacttc
    17581 ctgcggcagg atggtgatgc gacgacgcac ctcgttgtta cgcacttcag agataatcat
    17641 ctctttgcgg atctggttac gataggtgtt gtagttcaga ccatcgtaag ccagacggct
    17701 gcgcatctga tccagcgtca tgttgttctg tttcgcgatg ttagcaatcg cctgatccag
    17761 ctgctcatcg gagattttca ctcccatttt ctgccccatc tgcaggataa tttgatccat
    17821 gatcaaacgt tccatgattt ggtggcgcag cgtcgcgtca tcaggaagtt gttgccttgc
    17881 ctgagcagcg ttcagtttta ccgactgcat taatccatca acgtcgcttt ccagcacgac
    17941 gccgttattg acgacggctg cgactttatc gactacctgg ggggcagcga aactggtatt
    18001 cgcgatcatg gcgataccga gaagcagcgt tttccagttc ttcatacttt ttccatttca
    18061 attaaccgca ctgcggatta cgtggtaaat caacaaatca caaagtgttt tgatacggca
    18121 gaatgttcga acgcagcatc tcttgcgtac ccagaccgta gttggagctc aggccgcgaa
    18181 gttcgatgtt aaagccgatt gcgttgtcat ataccgcatg ttgtttatcg ttatcccaac
    18241 cgttcagctt ccgctcgtaa ccgacgcgaa tcgcatagca gcaggagctg tattgcacac
    18301 ctaacataga gtcggcttgc ttgttcgcat tggtgtcgta gtagtaggcc ccaacaatgg
    18361 accaacgatc ggcaattggc cagctggcga cggcacctac ctgcgaaata ccattcttat
    18421 attgctcagc agtggaatag tacttaggca gcgtagcctg aatatattcc gggctggcgt
    18481 aacggtaatt cagctgtacc agacggtctt catcacgacg gtattcaatg ctggagttac
    18541 tggtcgctac gttatccaga cgtgtatcgt actgaatccc gccacgcaat ccccaacgat
    18601 cggagatgcg ccagtaagta tcgcctgccc ataccagtga gcccgttttg tcgtcattct
    18661 cccatgttat gttgtcatcg ccagtgcgag actccgtgaa atagtagatt tgaccaacgg
    18721 aaatattaaa acgttcaacg gcagcatcat catatatgcg agatgtgaca ccggtcgtca
    18781 cctggttagc ggaggcaata cggtcaagac cgccgtaagt ccggtcccgg aacaggccgg
    18841 agtagtcaga ttgcagcagc gaagagtcgt agttatagat tttgctctga tcgcgatatg
    18901 gcacatacag atactgcgcg cgtggttcca gtgtctgggt atagcccggc gccagcattt
    18961 ccatatcacg ctcgaagacc attctaccgt ctaccttgaa ctgcggcatt acacggttag
    19021 cggactctgc cagcctggtc gtgtttctgg agttatacca gtcaagattg gtttgctgat
    19081 aatgggttgc cagcaacttc gcttcggtat tgatgctgcc ccagttatta gagagcggca
    19141 gattgatggt cggttccagg tgaacacggg ttgcttcagg catgtcgtct ctggtgttaa
    19201 caaagtgcac tgcctgaccg taaatacgcg tatcaaacgg accaacatca ttctggtagt
    19261 agttaacgtc taactgcggc tctgccgagt agctactggt gttctgctcg ctgaagacct
    19321 ggaactgctt ggttgaaacg gtggcattga agttttgcac cgcatagcca acgctgaatt
    19381 tttgcgttgc gtagccgtcg gtactggaac cgtatttgtt atcgaagtca ttgaagtagc
    19441 taggatcgct gactttggtg tagtcgacgt tgaaacgcca cacctgatcc atgaccccgg
    19501 agtggttcca gtagaacaac caacgacgtg aactgtcatc gttcgggtgt tcatctttat
    19561 agactttatc tgaaggcaga tagtccagtt ccatcaagcc agcgcccgcc tgggagaggt
    19621 agcggaattc gttctcccac atgatgttgc cacgacgatg catataatgc ggcgtgatgg
    19681 tggcatccat atttggcgcg atgttccagt aatatggcag gtagaactca aagtagttgg
    19741 tggtggtgta cttggcgttc gggatcaaga aaccagagcg acgtttgtca cccaccggca
    19801 actgcaaata cgggctataa aagatcggta ccggacccac cttaaagcgg gcgttccaga
    19861 tctccgcaac ttgttcttcg cggtcatgaa taatttcgct acctaccacg ctccaggtgt
    19921 cagaacccgg cagacaggag gtaaagctac cgttatccag aatggtatag cggttttcgc
    19981 cacgttgttt catcaggtcc gctttaccgc gcccctggcg acccaccatc tggtaatcac
    20041 cttcccagac gttggtatct ttggtgttca gattcgccca gcctttcggc cctttgagga
    20101 tcacctggtt atcgtcgtaa tggacattac cgagcgcatc aacggtacgt accggctccg
    20161 gttgtcctgg tgcctctttt tgatggagct gcacttcgtc ggcctgcaga cggctgttac
    20221 cctgcatgat atccacgctg ccagtaaaca cggcgtcatc cgggtagtcc cctttcgcgt
    20281 ggtcagcatt gatagtcacg ggtaagtcat tggtatcgcc ctgtaccaga ggacggtcat
    20341 agcttggcac gcccaacatg cactgtgagg cgaggtcggc tgccagtccc tgttgactat
    20401 aaagggcggt ggcaatcatg gtggccagga gagtggggat acgttttttc atacgttgat
    20461 tttattgttc catcatcggt aacgttgcgc gtgacaaacg gtcagagact aacgtactcg
    20521 tcatctctac gctagtgtta atcctgtccg aatagcgtca gtggtgttag gcacggcatt
    20581 gaatgacagg tatgataatg caaattatag gcgatgtccc acaattgacc gcagccggaa
    20641 aacggtaaaa gcacctttat attgtgggag atagccctga tatccgtgtg tcgatttggg
    20701 gaatatatgc agtattgggg aaaaatcatt ggcgtggccg tggccttact gatgggcggc
    20761 ggcttttggg gcgtagtgtt aggtctgtta attggccata tgtttgataa agcccgtagc
    20821 cgtaaaatgg cgtggttcgc caaccagcgt gagcgtcagg cgctgttttt tgccaccact
    20881 tttgaagtga tgggccattt aaccaaatcc aaaggtcgcg tcacggaggc tgatattcat
    20941 atcgccagcc agttgatgga ccgaatgaac cttcatggcg cttcccgtac tgcggcgcaa
    21001 aatgcgttcc gggtgggaaa atcagataat tacccgctgc gcgaaaagat gcgccagttt
    21061 cgcagtgtct gctttggtcg ttttgactta attcgtatgt ttctggagat ccagattcag
    21121 gcggcgtttg ctgatggttc actgcacccg aatgaacggg cggtgctgta tgtcattgcc
    21181 gaagagttag gcatctcccg cgcccagttt gaccagtttt tgcgcatgat gcagggcggt
    21241 gcacagtttg gcggcggtta tcagcagcaa tctggcagtg gtaactggca gcaagcgcag
    21301 cgtggcccga cgctggaaga tgcctgtaat gtgctgggcg tgaagccgac ggatgatgcg
    21361 accaccatca aacgtgccta ccgtaagctg atgagtgaac accatcccga taagttggtg
    21421 gcgaaaggtt tgccgcctga gatgatggag atggcgaagc aaaaagcgca ggaaattcag
    21481 caggcctatg agctgataaa gcagcagaaa gggtttaaat aagtttcaac gtgtaggcct
    21541 gataagacgc ggtaggccgg ataagacgcg ccagcgtcgc atccggcgag cagcatcaga
    21601 caatcggcgc acaattgccg gatgtggcgt gaacgcctta tccggcctac cgaacttcgc
    21661 cagcgtgact attaaaaatc cgctggtgct ttaaacgtca tactattgcc atacgccgga
    21721 tgggtaatcg tcagcatctc tgcatgtagc aacaaacgcg gtgccattgc tctcgcttct
    21781 ggtgatgcat aaaaacgatc gccgagaatc ggatgaccca gcgccagcat atgcacacgc
    21841 agctgatgcg aacgcccggt aatcggtttt aacaccactc ttgccgtgtt atccgccgca
    21901 tattccacca cttcatactc cgtctgcgca ggtttacctg tttcgtaaca gactttctgt
    21961 ttcgggcggt ttggccagtc gcaaatcagc ggcagatcca ccagaccttc cgcaggggat
    22021 ggatgccccc agacgcgggc cacatactgt tttttcggct cgcgctcgcg gaactggcgt
    22081 tttaactccc gctccgcggc tttggtcagc gccactacaa tcacgccgct ggtagccata
    22141 tccagacgat gcaccgattc tgcctgcgga taatcacgct gaatgcgcgt catcacgctg
    22201 tctttgtgct cttccagacg acccggcaca gacaacaaac cgctcggctt gttgaccacc
    22261 ataatatggt catcctgata caggacaacc agccagggtt cctgcggcgg attgtagttt
    22321 tccatcccca tcttcggctc cgttactgat gcgtcacaac gatcaaacgc agggcatcca
    22381 gacgccagcc tgcctgatcc aggctttcca ttacctgctg acggttgctc tcaatggcgg
    22441 tcagttcgtc gtcacgaatg ttcgggttaa ctgcacgcag cgcttccaga cgagacagct
    22501 cggcagacag tttttcgtcg gcttcgttac gcgctgcatc aatcaatgca cgggcagatt
    22561 tctcgatctg cgcttccccc agctgaagga tagcgtgaac atcctgctgc accgcgttaa
    22621 ccagcttgct gccggtgtga cggttaaccg cgttaagctg acggttaaag gtttcaaatt
    22681 ctacctgcgc cgccaggttg ttgccgtttt tatccagcag catacgtacc ggcgtcggtg
    22741 gcaggaagcg gttgagctgc aactgcttcg gagcctgggc ttcaaccaca taaatcagtt
    22801 ccaccaacag cgtacctacc ggcaacgctt tgtttttcaa cagtgaaatc gtgctgctac
    22861 cggtatcgcc agaaaggatc agatccagac cgttgcggat cagcggatgc tcccaggtaa
    22921 taaactgtgc atcttcacgc gccagcgcca cttcacggtc gaaggtgatg gtgatgccat
    22981 cttccgacag gccagggaag tccggcacca gcatatgatc ggacggcgtc agcacgatca
    23041 tgttgtcgcc gcgatcgtcc tgattgatac cgataatatc gaacaggttc atggcgaagg
    23101 cgatcagatt ggtatcgtca tcctgctctt caatgctttc tgccagtgcc tgggcttttt
    23161 cgccaccgtt ggaatggatc tccagcaggc ggtcacgccc ctgttccagt tgtgctttca
    23221 gcgcttcgtg ctgctcgcgg cagtttttga ttagatcgtc aaagccttcg gtctcatccg
    23281 gtgaagccag atagttaatc agatcgttgt atacgctatc gtaaatagtg cgtccggtcg
    23341 ggcaggtgtg ctcgaacgca tccagacctt cgtgatacca gcgcaccagc accgactgag
    23401 ccgttttttc cagataaggc acatggatct gaatatcgtg cgcctgaccg atacgatcca
    23461 gacgcccaat acgctgctcc agcagatccg ggttgaatgg caggtcaaac atcaccatgt
    23521 ggctggcgaa ctggaagtta cgtccttcag aaccgatttc cgagcacagc agtacctgcg
    23581 caccggtgtc ttcttcagca aaccaggcgg cagcgcggtc acgttcgata atcgacatgc
    23641 cttcgtggaa cactgcggcg cgaatacctt cacgttcgcg cagtacctgc tccagttgca
    23701 gcgcagtggc cgctttggcg cagatcacca gcactttctg agagcgatga ctggtcaggt
    23761 agcccatcag ccattcaacg cgcggatcga agttccacca ggtggcgtta tcgccttcaa
    23821 attcctgata aatacgctcc ggatagagca tatcgcgagc gcgatcttcc gcacttttgc
    23881 gtgcgcccat aatgccggag actttaatag cggtctgata ctgcgtcggc agtggcagct
    23941 taatagtatg cagctcgcgt ttcgggaagc ctttcacacc gttacgggtg ttacggaaca
    24001 gcacgcggct ggtaccgtgg cgatccatca gcatcgaaac cagttcctga cgggcgctct
    24061 gggcatcttc gctgtcgctg tttgctgctt gcaacagcgg ctcgatatcc tgctcgccga
    24121 tcatctcacc gagcatgttc agttcgtcat tgctgagttt gttacccgcc agcagcatgg
    24181 caacggcgtc cgcaaccgga cgataatttt tctgctcttc aacgaattgc gcaaaatcgt
    24241 ggaaacggtt cgggtccagc agacgcagac gggcgaagtg gctttccatc cccagctgtt
    24301 ccggggttgc ggtcagcagc agaacgcccg gcacgtgctc tgccagttgt tcaatggcct
    24361 gatattcacg gctcggcgca tcttcgctcc acaccaggtg atgcgcttca tcgaccacca
    24421 gtagatccca ctcggcttca cagagatgtt ccagacgctg tttgctacga cgggcaaaat
    24481 ccagcgagca aatcaccagc tgctcggtat cgaacgggtt gtaagcatcg tgctgagctt
    24541 cggcataacg ctcatcatca aacagagcaa agcgcaggtt gaaacggcgc agcatttcta
    24601 ccagccactg atgctgtaag gtttccggga cgataatcag cacacgttca gcagcgccag
    24661 agagcagttg ctgatgcagg atcatcccgg cctcaatggt tttccctaaa cccacttcgt
    24721 cagccaacag gacgcgcggc gcgtggcggc gaccaacatc atgagcgatg ttgagctggt
    24781 gcgggatcag gctggtacgc tgaccgcgca ggccgctgta cggcatacgg aactgttcgc
    24841 tggaatactt acgcgcgcga taacgcagcg caaagcggtc catacggtca atctgcccgg
    24901 caaacagacg gtcctgcggt ttgctgaaca ccagtttgct atcaaggaaa acttcacgca
    24961 gggccacgcc ggactcttca gtatcaaggc gagtaccgat ataggtcagc aagccatttt
    25021 cttcttttac ttcttcgact tgcatctgcc agccgtcatg gctggtaatg gtatcaccag
    25081 ggttgaacat cacgcgggtc acgggggaat cactgcgtgc gtacagacgg ttttcaccag
    25141 tagatgggaa aagtaaagtg acagttcgcg catccaccgc gacaacggtt ccaagtccca
    25201 attcgctttc tgtatcgctg atccagcgtt gaccaagtgt aaaaggcata tgtgttcggc
    25261 tctatatctt taattgcagg caataaccac ccgctaccgt gcttatgagg tagtggtgtt
    25321 attcaggtcc aggaatggaa agggcgctat ggtactggat ggcaaagcat tcgtcacgca
    25381 tcaaaatggt atctggcgaa ctcttttttt tgctcaaaat agcccaagtt gcccggtcat
    25441 aagtgtagca aaattatcct caataaaagg gagtattccc tccgctacgg gttgtagctg
    25501 gcgggtcaga tagtgttcgt aatccagtgg tgaacgttgg tagtccagcg gctccgggcc
    25561 gttggtggtc catacgtact taatggtgcc gcggttctga tattgcaagg ggcgaccgcg
    25621 cttatggttt tcttcatcgg caaggcgagc ggcgcgtaca tgaggcggca cattacgctg
    25681 atattcgctc agcggacggc gaaggcgttt acggtaaacc agccgcgcat ccagttcacc
    25741 cgccatcagt ttgtcgatgg tttcacgcac gtattcctga tatggctcgt tgcggaagat
    25801 acgcaggtaa agctcctgct gaaactgctg ggccagtggc gtccagtcgg tgcgcacggt
    25861 ttccagccct ttaaacacca tccgctgttt gtcgccctcc tgaatcagtc cggcgtagcg
    25921 ctttttgctg ccggtatcgg ccccgcgaat ggttggcatc agaaaacggc agaaatgggt
    25981 ttcatactcc agttccagtg cgctggtcag ccgttgtttt tgcagcgttt ccgcccacca
    26041 ggcgttaacg tgctgcacca gtgcacgacc gattttcgct gcttcttctt ccgaatgtgc
    26101 acctttcagc cagacaaacg ttgagtcggt atcgccgtag ataacgtcat agccctgcgc
    26161 ttcaatcaac gttttggttt gccgcatgat ctgatgacca cgcatggtga tcgacgatgc
    26221 caggcgtgga tcgaagaaac ggcaggcggt ggtgccgagc acaccataaa aggcattcat
    26281 aatgatcttc agcgcctgcg aaagcggctt attaccctga cgtttggctt catcgcgccc
    26341 gtgccagatg ttagtcacaa tctccggcag gcaatgtttc tcccgtgaga accacgcatc
    26401 gagaaaacct tcggtactgt gctctggatc aggctgcgcc atgccttcca ccagcccgac
    26461 gggatcaatc agaaaggtgc ggatgatcga cgggtacagg cttttgtagt ccagcaccag
    26521 caccgaatca taaagcccag gtcgcgaatc catcacgtag ccgccagggc tggcgtgcgg
    26581 cggcacttcg ccgagattag gcgcgacata accagcgcga tgcatacggg gaaaatagag
    26641 atgaccaaac gctgccaccg aaccgccgtg tcgatccacc ggcaggccgt tcaccgtcgc
    26701 ccgttcgagc aaaaacggca taatttcagt tttgtggaag atctgcgtca ccagctcgca
    26761 atctttcagg ttataagttg ccagcgcagg tttatcttcg gcgaaacggc ggtcaatttc
    26821 gtccattcga tcccacgggt tatcgataga ttttccttcg cctaataact cctgagcgac
    26881 ggtttccagc gagaatgaag agaaattcca gaacgcggat ttcagcgcct cgataccgtc
    26941 gataattagc cgacctttaa cctgagcaaa aaacacaccg tttttaaagc cgtgctcgcg
    27001 ccactccagc tcactgttat cacgccccag ccgcagcgga atacggtaac gctcggcatg
    27061 tttttgcagc attcgcagat cgaactgcac cacgttccaa ccgatgatca catcaggatc
    27121 gtagttggca aaccaggcgt taagtttttc cagtagcagc gggcggctgg cgacgtattc
    27181 cagttcaaaa tcgagcgcgg aggcgtcgcc attctctggc cccagcatat aaacgatacg
    27241 ctgcccgcaa ccttccaggc cgatgcagta cagctcaccg tggcgggtgg tttcaatatc
    27301 aatagaaacc cacttgagcg gcggacgata gtcgggatgc ggtttcagac gggcattaac
    27361 gatagcgcca ttgcgcatat caccctcgac ccacaccggt gaggtgataa atcgctccat
    27421 cagatagcgt tctggcgggc gcacatcggc ctcgtagacg gtaacgccac cttcacgcag
    27481 gcgcttttcg taattcatca actggcgatg ggcgcgacag taaaggccat acaccggctg
    27541 gcggtgaaaa tcttttaacg ccagcggcgt caggcgaaag ccttgttcac cctgcaaaat
    27601 atgctgagcg cggggaacct gatcggcagg aataaacgcc acggactctt gcggcgcaag
    27661 gaaaacctgc aacggcccgt tgtccgtcgc cagccagaag gaaacttcgg tcccttgcgg
    27721 ggtgtcccgc cagtgtcggg ttaagataaa acctgcctgc gccacgctga aaatccaata
    27781 aaaaaccagg cttgattata gcctggtttc gtttgattgg ctgtggtttt atacagtcat
    27841 tactgcccgt aatatgcctt cgcgccatgc ttacgcagat agtgtttatc cagcagcgtt
    27901 tgctgcatat ccggtaactg cggcgctaac tgacggcaga atatacccat ataagcgacc
    27961 tcttccagca cgatggcatt atgcaccgca tcttcggcat ttttgcccca tgcaaatggg
    28021 ccgtgagaat ggaccaggac gccgggcatt tgcgctgcat cgataccctg tttttcgaag
    28081 gtttctacga tgacgttacc ggtttcccac tcatattcac cgttgatttc tgcgtcggtc
    28141 attttgcggg tgcagggaat gggaccgtag aaatagtcgg cgtgggtggt accggttgcc
    28201 ggaattgact gacccgcctg cgcccagatg gtggcgtggc gcgagtgtgt gtgcacaatg
    28261 ccgccaatgg acgggaatgc ctgatagagc agccggtgag ttggcgtgtc ggaggagggc
    28321 tttttcgtac cttcaaccac ttcaccggtt tcgatgctga ccacgaccat atcgtcagcg
    28381 gtcatgatgc tgtagtcgac gccggaaggt ttgatcacaa agacgccgcg cccgcgatca
    28441 acggcgctga cgttgcccca ggtgagcgtg accaggttgt gttttggcag cgccaggttg
    28501 gcttctaata cctggcgttt gagatcttct aacatgttga ctccttcgtg ccggatgcga
    28561 tttgcttatc cggcctacaa aatcgcagcg tgtaggcctg ataagacgcg tcggcgtcgc
    28621 atcaggcgtt acatacctga tgcggctact tagcgacgaa atccgtaata cacttcgttc
    28681 cagcgcagcg cgtctttaaa cgctggaagg cgggtatcgt tatcaatcac cgtgatttca
    28741 atgtcgtgca tctcggcgaa ctggcgcata tcgttgaggt tcagcgcatg gctgaagacg
    28801 gtatggtgcg cgccaccggc aaggatccac gcttcggaag cggtcggcag atccggttgc
    28861 gctttccaca gcgcattcgc caccggcagt ttcggcaggg agtgcggtgt tttcaccgtg
    28921 tcgatgcagt taaccagcag acgataacga tcgccgagat caatcaggct ggcgacaatg
    28981 gccggaccag tttgagtatt gaagatcagg cgagccgggt cgtctttacc gccaatacca
    29041 aggtgctgaa cgtcgaggat cggtttctct tccacagcga tcgacgggca gacttccagc
    29101 atatgggagc cgagtaccag gtcattacct ttctcgaagt gataggtgta gtcctccata
    29161 aaggaggtgc cgccctgcag accggttgac atcaccttca tgatgcgaag cagggcggca
    29221 gttttccagt cgccttcgcc cgcaaagccg tagccctgct gcatcagacg ctgtacggcc
    29281 agaccaggaa gctgtttcag gccgtgcaaa tcttcaaagg tagtagtgaa agcgtggaag
    29341 ccaccctgtt ccaggaaacg cttcatcccc agctcaatac gcgccgcttc cagcacgttc
    29401 tgtcgttttt cgccgtggat ttgtgtggca ggtgtcatgg tgtagcagct ttcgtactca
    29461 tcgaccagcg cgttaacatc gccgtcgctg atggagttca ccacctgcac cagatcgcca
    29521 accgcccagg tattgacgga gaaaccaaac ttgatctgtg cggcaacttt atcgccatcg
    29581 gtgaccgcta cttcacgcat gttatcgcca aaacggcaga ctttcagatg acgggtatcc
    29641 tgtttagaga ccgcctgacg catccaggag ccgatacgct catgtgcttg tttatcctgc
    29701 cagtgaccgg taacaacggc atgttgctga cgcatacgcg cgccgatgaa gccgaactcg
    29761 cgaccgccat gcgcggtctg gttcaggttc ataaagtcca tgtcgatgct gtcccacggc
    29821 agcgccgcgt tgaactgggt gtggaattgc agcaacggtt tgttgagcat ggtcaggccg
    29881 ttgatccaca ttttggccgg ggagaaagtg tgcagccaca ccaccagacc agcgcaacga
    29941 tcgtcgtaat tcgcgtcgcg gcaaatagcg gtgatttcat ccggcgtggt gcccagcggt
    30001 ttcagcacca gtttgcaggg caacttcgct tctgtattca gtgcattaac aacgtgttcc
    30061 gcatgttgcg tcacctggcg cagagtctcc gggccgtaaa gatgctggct gccaattaca
    30121 aaccacactt cataattatc aaaaatcgtc attgtcgtgt ccttatagag tcggaacggc
    30181 ctgggcagcc tgtgccgggg cggaagttgg aagatagtgt tgttcggcgc tcatcgccca
    30241 ttgctgatag cggcgataaa gctgttcaaa gcgttgtgcc tgttcgctgc gcggttgcag
    30301 ggttttctct accgcactgg ccattttttg ctgggctgat gggatgtctg cgtgcacttt
    30361 cgcggcgaca gcagcaaaaa tcgccgcacc gagcgcacag cactggtcag aggcaacaat
    30421 ttgcagcggg cgattcagca cgtcgcagca ggcctgcata atgacctggt ttttccgcgc
    30481 gatgccgccc agcgccatca cgttattgac ggcgatcccc tgatcggtaa agcactccat
    30541 gattgcgcgt gcgccaaagg cggtggcagc aatcaaaccg ccgaacagca gcggagcgtc
    30601 ggtagcgagg ttcagatcgg taatcacccc tttcaggcgt tggttagcgt tcggtgtgcg
    30661 gcggccgtta aaccagtcga gcaccaccgg taggtgatcc agagacggat tttgagccca
    30721 tacttcggtc agcgccggaa gcagttgttt ctggctggcg ttgatttgct ctttcagttc
    30781 cggatgctgg gcggcaagct gttccagcgg ccagccgagt acgcgaccaa accaggcgta
    30841 gatatcccca aacgccgatt ggcctgcttc cagaccgata aatccaggca ccacgctgcc
    30901 atcaacctga ccgcaaatac ctttcactgc ccgctcgcca acgctctgtt tgtcggcaat
    30961 cagaatgtca caggtggaag taccgataac ttttaccagt gcgttaggct gtgcgcctgc
    31021 gccaactgcg cccatatggc agtcaaacgc gccgccggaa atcactacgc tttcaggcag
    31081 gccgagacgc tgcgcccatt ccgggcataa ggtgcccacc ggaatatcgg cagtccaggt
    31141 atcagtgaac agcggggaag gcaaatggcg attgaggatc gggtccagct catcaaagaa
    31201 actggctggc ggcaggccac cccagctttc gtgccacaga gatttatgcc cggcgctgca
    31261 acgtccgcga cgaatatcct gcgggcgggt ggtaccggaa agcagagctg gcacccagtc
    31321 gcacagctca atccatgatg cggcagattg tgccacggcg ttgtcctggc gagttacatg
    31381 caggattttt gcccagaacc attcgctgga ataaataccg ccaatattgc gggagtagtc
    31441 aacgttgccc ggcgtgtgac ataagcgggt aatctcttcc gcttcttcaa ccgcggtgtg
    31501 gtctttccac aatacgaaca tcgcgttcgg gttctcggca aactccgggc gcagcgccaa
    31561 cacgttgccg tcggcgtcaa tcggtgcggg cgtcgagccg gttgtgtcaa cgccaatccc
    31621 gaccacagct gcgcgctgtt cgacgcaaag ctctgcaagc acagttttca gcgccgcttc
    31681 cattgactca atgtagtcac gcggatgatg acggaactgg ttattcgggg catcacaaaa
    31741 ttgcccgttc tgccaacggg gataccactc tacgctggtg gcgatctctt caccagtggc
    31801 gcattccacc gccaaagctc gcacagaatc actgccaaaa tcgaggccaa ttgcaatcgc
    31861 catcgtttca ctccatccaa aaaaacgggt atggagaaac agtagagagt tgcgaaaaaa
    31921 aacgtcaggc tggatccgct aatcttatgg ataaaaatgc tatggcatag caaagtgtga
    31981 cgccgtgcaa ataatcaatg tggacttttc tgccgtgatt atagacactt ttattacgcg
    32041 tttttgtcat ggctttggtc ccgctttgtt acagaatgct tttaataagc ggggttaccg
    32101 gttgggtcag cgagaagagc cagtaaaaga cgcagtgacg gcaatgtctg atgcaatatg
    32161 gacaattggt ttcttctctg aatggcggga gtatgaaaag tatggctgaa gcgcaaaatg
    32221 atcccctgct gccgggatac tcgtttaacg cccatctggt ggcgggttta acgccgattg
    32281 aggccaacgg ttatctcgat ttttttatcg accgaccgct gggaatgaaa ggttatattc
    32341 tcaatctcac cattcgcggt cagggcatag tgaaaaacca gggacgagaa tttgtctgcc
    32401 gaccgggtga tattttgctg ttcccgccag gagagattca tcactacggt cgtcatccgg
    32461 aggctcacga atggtatcac cagtgggttt actttcgtcc gcgcgcctac tggcatgaat
    32521 gggttaactg gccgtcgata tttgccaata ccggtttctt tcgcccggat gaagcgcacc
    32581 agccgcattt cagcgacctg tttgggcaaa tcattaatgc cggacaaggg gaagggcgct
    32641 attcggaatt gctggcgata aatctgcttg agcaattgtt actgcggcgc atggaagcga
    32701 ttaacgagtc gctccatccg ccgatggata atcgggtacg cgaggcttgt cagtacatca
    32761 gcgatcacct ggcagacagt aattttgata tcgccagcgt cgcacagcat gtctgcctgt
    32821 cgccgtcgcg tctgtcgcat ttgttccgcc agcagttagg gattagcgta ttaagctggc
    32881 gcgaggacca gcgcatcagt caggcgaagc tgcttttgag caccacccgg atgcctatcg
    32941 ccacagtcgg tcgcaatgtc ggttttgacg atcaactcta tttctcgcga gtatttaaaa
    33001 aatgcaccgg ggccagcccg agcgagttta gggctggatg tgaataataa gaaagaaggg
    33061 ggagtctctt actttcgtta cctgacgtta tttatatatg ttacggataa ttaattttat
    33121 tttatttgta agctaaatat taattatctt taggtgaatc gtttcgcctg aataatattt
    33181 tt
//
LOCUS       DAPOXO010000057        33027 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPOXO010000057 DAPOXO010000000
VERSION     DAPOXO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33027
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.057"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            183..1841
                     /locus_tag="ROH59_003107"
     CDS             183..1841
                     /locus_tag="ROH59_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HDX4805556.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENIPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(1838..2794)
                     /locus_tag="ROH59_003108"
     CDS             complement(1838..2794)
                     /locus_tag="ROH59_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001351020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF535 domain-containing protein"
                     /protein_id="HDX4805557.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFCS"
     gene            2945..4060
                     /gene="macA"
                     /locus_tag="ROH59_003109"
     CDS             2945..4060
                     /gene="macA"
                     /locus_tag="ROH59_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HDX4805558.1"
                     /translation="MKKRKTVKKRYVIAMVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDNAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKINDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            4057..6003
                     /gene="macB"
                     /locus_tag="ROH59_003110"
     CDS             4057..6003
                     /gene="macB"
                     /locus_tag="ROH59_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HDX4805559.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLEWKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVRNPPAIEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(6076..6300)
                     /gene="cspD"
                     /locus_tag="ROH59_003111"
     CDS             complement(6076..6300)
                     /gene="cspD"
                     /locus_tag="ROH59_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HDX4805560.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            6623..6943
                     /gene="clpS"
                     /locus_tag="ROH59_003112"
     CDS             6623..6943
                     /gene="clpS"
                     /locus_tag="ROH59_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HDX4805561.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            6974..9250
                     /gene="clpA"
                     /locus_tag="ROH59_003113"
     CDS             6974..9250
                     /gene="clpA"
                     /locus_tag="ROH59_003113"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HDX4805562.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(9594..9681)
                     /locus_tag="ROH59_003114"
     tRNA            complement(9594..9681)
                     /locus_tag="ROH59_003114"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9645..9647),aa:Ser,seq:gga)
     gene            complement(9935..10153)
                     /gene="infA"
                     /locus_tag="ROH59_003115"
     CDS             complement(9935..10153)
                     /gene="infA"
                     /locus_tag="ROH59_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDX4805563.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(10438..11142)
                     /gene="aat"
                     /locus_tag="ROH59_003116"
     CDS             complement(10438..11142)
                     /gene="aat"
                     /locus_tag="ROH59_003116"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HDX4805564.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFS
                     RMENASKTALLVFCDEFIRHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LSNNFWVPRCLFSPQE"
     gene            complement(11184..12905)
                     /gene="cydC"
                     /locus_tag="ROH59_003117"
     CDS             complement(11184..12905)
                     /gene="cydC"
                     /locus_tag="ROH59_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HDX4805565.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPKVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGIYLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEIL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(12906..14672)
                     /gene="cydD"
                     /locus_tag="ROH59_003118"
     CDS             complement(12906..14672)
                     /gene="cydD"
                     /locus_tag="ROH59_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HDX4805566.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLFLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQTALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(14795..15760)
                     /gene="trxB"
                     /locus_tag="ROH59_003119"
     CDS             complement(14795..15760)
                     /gene="trxB"
                     /locus_tag="ROH59_003119"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDX4805567.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNTDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
     gene            16304..16798
                     /gene="lrp"
                     /locus_tag="ROH59_003120"
     CDS             16304..16798
                     /gene="lrp"
                     /locus_tag="ROH59_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HDX4805568.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            16933..21039
                     /gene="ftsK"
                     /locus_tag="ROH59_003121"
     CDS             16933..21039
                     /gene="ftsK"
                     /locus_tag="ROH59_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDX4805569.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDE
                     EITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWA
                     APVEPVTQTPPVASVDVPPAQSTVAWQPVPGPQTGEPVIAPAPEGYPQQPQYAQPAVQ
                     YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAAEQPAQQPYYAPA
                     PEQAVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPV
                     VEETKPTRPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVP
                     PVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKR
                     IRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFA
                     QTQQQRYGEQYQHDVPVNTEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDF
                     EFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPV
                     APQQQYQQPQQPVAQQPQYQQPQQPVTQQPQYQQPQQPVVPQPQYQQPQQPVAPQPQD
                     TLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADF
                     RIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPY
                     VGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAG
                     TTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDA
                     ANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQH
                     PVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVIT
                     GLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVR
                     DQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRK
                     ASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD"
     gene            21198..21809
                     /gene="lolA"
                     /locus_tag="ROH59_003122"
     CDS             21198..21809
                     /gene="lolA"
                     /locus_tag="ROH59_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HDX4805570.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            21820..23163
                     /gene="rarA"
                     /locus_tag="ROH59_003123"
                     /gene_synonym="mgsA"
     CDS             21820..23163
                     /gene="rarA"
                     /locus_tag="ROH59_003123"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HDX4805571.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAVGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            23254..24546
                     /gene="serS"
                     /locus_tag="ROH59_003124"
     CDS             23254..24546
                     /gene="serS"
                     /locus_tag="ROH59_003124"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDX4805572.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            complement(24852..24992)
                     /locus_tag="ROH59_003125"
     CDS             complement(24852..24992)
                     /locus_tag="ROH59_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HDX4805573.1"
                     /translation="MSQKSLTAITFCVTAILIIWMLHGSLCEIRMSFWGAEFAAFLQC
                     KQ"
     gene            complement(25184..25444)
                     /locus_tag="ROH59_003126"
     CDS             complement(25184..25444)
                     /locus_tag="ROH59_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001512982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HDX4805574.1"
                     /translation="MFRCPLCGASARIRTSRPENDSNTVRQKYYQCNNLECGVCFSTL
                     EAFHKFTSKHASGVHSSEGIPWHDLPASHRGNNQMSLPLSQN"
     gene            complement(25485..26594)
                     /locus_tag="ROH59_003127"
     CDS             complement(25485..26594)
                     /locus_tag="ROH59_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001494339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HDX4805575.1"
                     /translation="MTDTTMQLLSQGTDPVKMPDFDILAEGKTLSGVAERLMSLSLTD
                     NRGFEADQLTITLDDADGQLQLPPRGARLTVLIGWKGEPLTEKGTYIVDEIAHEGPPD
                     RLTVSARSADFRDEFNVKREVSWHDVTVERVVSAIAHRYGLKPQISEMLMDIEIDHAD
                     QTEESDMSFLTRMAEMLGAITTVKSGNLLFIMPGGGVNAQGQPLPSFAITRSSGDRHQ
                     FRIADREAYTGVRAYWLDLNYGKKKKVSVKRRKPPKPKKEKSSSREGDYMEGAEGNVF
                     VLRKTYQNEQAARRAAAAKWQQLQRGAASFSITLARGRAELYPEMHGTVTGFKSEIDN
                     QDWIIAKAEHTIDNSGFTTQLELEAKIPEWIAETE"
     gene            26752..27936
                     /locus_tag="ROH59_003128"
     CDS             26752..27936
                     /locus_tag="ROH59_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HDX4805576.1"
                     /translation="MSETRFHGARVTESTDLVTAINDVDSSVIGIVATADDADAELFP
                     LNKPTLLTRVNDVLGKCGTTGTLYRALKAIADQVSTKVIVVRVAEHKEEGGRTQDQLV
                     IGGSESDGSYTGMYALLVAEQDESIGYRPRILAAPELDTEAVTKSLCVIAGKLRAFVY
                     ATCHGCNTMAEAITYRQKFNEREVMLLWPDFIAYNPKSGKNETFPAPAYACGLRAYID
                     HEQGWHKSLSNVPVKNVLGMSRHVFWSLQAEDSDANSLNNKEITTIIRRNGFRFWGNR
                     TPETNAYIFEVYTRTAQVLADSIAEAQFETIDSPLTPANVKDVISAIRAKLDSLVTAG
                     KLIGAECWYDVVDNGTTDLRQGRVRIRYKYTPVPPLEDMELYQTFTDEFFGPAFAVLG
                     GA"
     gene            27936..28448
                     /locus_tag="ROH59_003129"
     CDS             27936..28448
                     /locus_tag="ROH59_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HDX4805577.1"
                     /translation="MAVPKHLRFFTLFVDGENEVGKVTSVTPPKLTRKTDSYRGGGMM
                     GAVSIDLGLDDSALDASFVMGGAVRALFLKYGGTIDGTLLRFAGEYYTDAESDLYEIE
                     MRGRVTEIDMGEAKQGEATSHTYAVKNTYYKLSVNDRPLWEIDLLNHIYRKDGKDIVP
                     DRIRSALGLG"
     gene            28504..28878
                     /locus_tag="ROH59_003130"
     CDS             28504..28878
                     /locus_tag="ROH59_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4805578.1"
                     /translation="MKDIDTETRNNTVADDVTSGEDMAVERGVKLSRPIERGAEKITY
                     VEITGAIEQAGSLRGLSLSDVLNLKADTMFTLLPRVTSPRLDEVMIKKMSSRDFIQLC
                     AVAVNFMSEPDSGAKSVQETAA"
     gene            28887..29042
                     /locus_tag="ROH59_003131"
     CDS             28887..29042
                     /locus_tag="ROH59_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HDX4805579.1"
                     /translation="MCFEHIEDLVADIAAIFNWSPAEIFMMTPGEVVSWRERAALRSG
                     NADNEDS"
     gene            29029..31836
                     /locus_tag="ROH59_003132"
     CDS             29029..31836
                     /locus_tag="ROH59_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000853438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDX4805580.1"
                     /translation="MKTLDIRVAFSAVDRLTRPAENARRLMGQFGDSIQRTQGAIKNL
                     ERQARSFERARDAVSKADAGIVKARRQLNALNQLQRTGTVLSEKQQKLMQQLSTRLER
                     LNESRTREIQKMRELGGELKRHGISLTGSDNTIQQAIRRTEQYNNQLERERQALARVT
                     QARERYSRAQETAGKLKTGGALAIGAAAAGGYAAGRFLQPAIGFGKEMSRVQALTRID
                     KNSPQFKALREQALKLGSETQFTASDAASGQSFLAMAGFTPQAIQAALPGVLNMALAG
                     GVELGETADIGSNILTQFNLTADQMDRVGDTLTAAFTRTNTDLRALGETMKYTGPVAA
                     KLGISLEEAAAMAGMLANNGLRGSDAGTAMRASLSRLASPPKAAADALKELGVSVADA
                     RGKMRPMEDVLLDLYKATQKYGQVDQVSFFKDIAGEEAFVGLQTLVAAAGSGELQKLT
                     RELQGARGEADRVAKVMADNLDGDLKNLDSAWEGLRIRISDLVDGPLRSVTQWLTRVL
                     EKITSLAQAHPVLTRQLLIAGGALLAMTATVGSLSLAIGVLAGPLAKLRLGFSLLTGS
                     MNAVRLLPALWGMVTGSVSLLGGAIGALFSPVGLIVAALAGAAVLIWKYWDPIRAFFA
                     GVFSGIMERLTPLRETFERFGPVFDAIGSGISQVFNWFKSLLSPMESSKETLDKCTSA
                     GEIFGNVLGGALQLVLTPAKMLLDTLAWILEKLGVLPDEAERARKKIEDAQRAAILQD
                     KVALLQGDLAKINPPKPVENGNGTGGDNPKDNKPLTDSNTGTLRRLSKIADNTGKLVE
                     ETKKRIGPGDIVFKNLPRALAVRGEWQERKIAQVSKPAPAINITPVVPAPLPPALVPV
                     VAASSRPVAEAIRSPVASVPVTSRNREPVASGFGGEIHVHLHNVVTQNPRELAKLVGE
                     MVRAEMERRARAGRGSFYDKD"
     gene            31849..32337
                     /locus_tag="ROH59_003133"
     CDS             31849..32337
                     /locus_tag="ROH59_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4805581.1"
                     /translation="MMMIYGMFVFELRTLPHQQLQQNKSWRHVKNERVNRSASWQYIG
                     AGDDRIVLSGVLYPEITGGEVSLSLLTTQAYTGRPWPLIDGVGQIYGMYVLTETNTTR
                     SEFDRYGKAKKIEFSLTLERCDEDLRERLQSSSFSDMLSGFKDKVTSSLNSAASSVKG
                     LF"
     gene            complement(32366..32965)
                     /locus_tag="ROH59_003134"
     CDS             complement(32366..32965)
                     /locus_tag="ROH59_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDX4805582.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALVCAGCEQIFEDKLSGTKTDRPG
                     LKRALKRLQKGDTLVVWKLDRLGRSMKHLISLVGELRERGINFRSLTDSIDTSSPMGR
                     FFFHVMGALAEMERELIVERTLAGLAAARARGRTGGRRPKLTKEQHEQIARLIKNGHD
                     RKQLAIIYGIGTSTIYRYHPVGDIQTEETTGQTQENENR"
BASE COUNT         7999 a         8201 c         9041 g         7786 t
ORIGIN      
        1 tatcatgcta attatttgat tttgttgttt ttgcaggctt atcagcaaga gggagtataa
       61 cgcgattatt cgctcatttt tcagacattt gccatgctta aatgtgatgc catcacgtat
      121 tagcaggcct ttcccgttat actgccagcg taaagaataa gtcacatatt tctggagggg
      181 atatgattct tgagcgcgtt gaaattgtgg gttttcgcgg tatcaaccgt ttgtcgttga
      241 tgctggaaca aaacaacgtc ctgattgggg agaacgcgtg gggtaaatcc agcttgctgg
      301 acgccttaac cctgctgcta tcgccagaat cagatctcta ccattttgag cgcgatgatt
      361 tctggttccc gccgggagat atcaacgggc gagaacatca tctgcatatt attttgacct
      421 tccgcgaatc gctgccaggc cgacatcggg ttcgccgcta tcggccgctg gaagcgtgct
      481 ggacgccatg caccgatggt tatcaccgta ttttttatcg tctggaaggg gagagtgcgg
      541 aagacggcag cgtgatgaca ctgcgcagtt ttctcgataa agacggacat ccgattgatg
      601 ttgaggatat taacgatcag gctcgtcatc tggtgcgttt aatgccggtg ctgcgcttgc
      661 gtgatgcccg ttttatgcgc cgtattcgta acggcacggt gccaaatgtc cccaatgtgg
      721 aagtcaccgc gcgccagctc gatttcctcg cccgtgagtt gtcctcacat ccgcaaaatc
      781 tctctgatgg acagattcgt cagggacttt ccgcaatggt gcaactgctt gagcattatt
      841 tttctgagca gggagctgga caggcgcgat atcgtttaat gcggcggcga gccagcaatg
      901 agcaacgaag ctggcgctat ctggatatca tcaaccggat gattgaccga cctggagggc
      961 gctcgtatcg ggttattttg ctcggcctgt ttgctacttt gttgcaggca aaaggcacat
     1021 tgcgactgga taaagacgcc cgtccattgt tgctgatcga agatccagaa acccgtttgc
     1081 accccattat gctttcagtt gcctggcatc tgttgaacct tctgccattg cagcgcatcg
     1141 ctactaccaa ctcgggagag ttgctttcgt taacgccggt agagcatgtt tgccgactgg
     1201 tacgtgagtc ctctcgcgtt gccgcctggc gtctgggacc gagtggcttg agtaccgaag
     1261 atagccgacg catctccttt cacattcgtt ttaaccgtcc gtcatcgctg tttgcccgtt
     1321 gttggctgct ggtggaaggg gaaacggaaa cctgggttat caatgaactg gcgcgtcagt
     1381 gcggacatca ttttgatgcc gaagggatca aggtcattga gtttgcccag tccgggctaa
     1441 agccactggt taaatttgcc cggcgaatgg ggattgaatg gcatgtactg gtcgatggcg
     1501 atgaagcagg gaagaaatat gccgctacgg tacgcagcct gttgaataat gatcgggaag
     1561 ccgaacgaga acatttaacg gcgttaccgg cgctggatat ggaacatttt atgtatcgcc
     1621 agggattttc cgatgtgttc caccgcgtgg cgcaaatccc ggaaaatata ccgatgaatc
     1681 tgcgcaaaat tatctcgaaa gcgatccatc gctcttccaa acccgatctt gccattgaag
     1741 tggcaatgga ggccggacgt cgtggtgtgg actccgtacc gacgctgctg aaaaaaatgt
     1801 tctcacgcgt gctgtggctg gcgcgcggtc gggccgacta actacaaaac atcgtggcca
     1861 tttgtggctg aatagcgtcg agcatctcat agcgccgacg gtattcagcc cgttttttac
     1921 tggcgatttc ggcaatctct tttcgtgcta tctgtgctgg aaggcggtaa tggcgttcag
     1981 catcacatac gccgccaact gattcccaga aagcgttgta atcggcatgg atcttgcctt
     2041 ctttatcgcg ataacgcagg ctgcggtaaa tatgcgtttc attgctgacg gcaataatct
     2101 gctctacctg caaacgttgg gcaaacagac aggccgcttc catcacgagg cgtttgggaa
     2161 atagcccgtg gcaggctttc gtcgcattct ggatttcctg gtgtggaatt tcccattttg
     2221 cgccttgcag tccgccaata aacatcgtcc ttttcccctg atattcacac agggtaaaag
     2281 tgagctctgc cagaggaata ccttcgctgt tgcggaacag gatggtgctg tcaccttctt
     2341 tatccattga gatcatcatg gtcagctcaa gcgtgaactg ctcgccgttt ttgccttcca
     2401 gcttcgccag ttgcagcccg ggggtattca aatataagct gaattcttcc gccgacatac
     2461 acccgcggag taacgcataa tggtaacgta acgcctccag caattgctta cggctaagat
     2521 tcgccgcaag gtaagggcga tgtagacgta caggcagtcg cggctggcgc gttaacaaca
     2581 cattgagatt aggccagtgg gaaagttcgt tcatccactc aacgcttaaa cgcggcataa
     2641 tcaacgagcg cagcaaaaat ttctggcgaa aactacggcg atgccagaat ttacccggcc
     2701 gacactgtcc tcgtgccaga ctaagaaaaa gtgacaggct gctgagagat tcagatggcg
     2761 taaaggtccg ttcagttagc tgcgacatat tcatgaaatc aatggttata catgacgtcg
     2821 atttaaccat tgcgtatctt aaccaaacat caatagtgtg attattaacg taaattttag
     2881 ggttttgttg atatttcgtt gaagttaatg acccggattg gcatatggag tattcagaat
     2941 atttatgaaa aagcggaaaa ccgtgaagaa gcgttacgtt attgcgatgg tgatagtcat
     3001 cgccgggctg attacgttat ggagaattct taacgcaccc gtgccgactt atcagacgct
     3061 gattgtgcgc cccggtgatt tacagcaaag cgtgctggcg accggaaagc tggacgcgct
     3121 gcgtaaggtt gacgtgggcg cgcaggtcag cggtcagttg aaaacgctgt cggtggcgat
     3181 tggcgataaa gtaaaaaaag accagctttt aggggttatt gatcctgaac aggctgaaaa
     3241 ccagatcaag gaggtggaag caacgctgat ggagctacgc gcgcagcggc agcaggcgga
     3301 agcggagctg aaactggcgc gggtgacgta ttcccgtcag caacgtcttg cacaaacgca
     3361 agcggtttca cagcaggatc tcgataacgc cgcgacggag atggctgtga aacaggcgca
     3421 aattggcacc attgacgcgc aaatcaagcg caatcaggcc tctctcgata cggctaaaac
     3481 caatctcgat tacacccgca tcgttgcccc gatggccggg gaagtcacgc aaatcaccac
     3541 tctgcaaggc cagacggtga ttgccgcaca acaagcaccg aacattctga cgctggcaga
     3601 tatgagcacc atgctggtaa aagcgcaggt ttctgaagcg gatgtaatcc acctgaagcc
     3661 ggggcaaaaa gcctggttta cggtgcttgg cgatccactg acgcgctacg aggggcaaat
     3721 caaggatgtg ctaccgacgc cggaaaagat taacgacgct attttctatt acgcccgttt
     3781 tgaagtaccc aaccccaatg gtttactgcg gctggatatg accgcgcaag tgcatattca
     3841 gctcaccgat gtgaaaaatg tgctgacgat ccctctgtcg gcgttaggcg atccggttgg
     3901 cgataatcgt tataaagtca aattgttgcg taatggtgaa acacgcgagc gtgaagtgac
     3961 gattggcgca cgtaacgata ccgatgttga gattgtcaaa gggctggaag cgggcgatga
     4021 agtggtgatt ggtgaggcca aaccaggagc tgcgcaatga cgcctttgct cgaattaaag
     4081 gatattcgtc gcagctatcc tgccggtgat gagcaggttg aggtgctgaa gggcatcagc
     4141 ctcgatattt atgccggtga gatggtagcg attgtcggtg cttcgggttc tggtaaatcg
     4201 accctgatga atattctcgg ctgcctggat aaggccacca gcggcaccta tcgcgtcgcc
     4261 ggtcaggatg ttgccacgct ggacgccgat gcgctggcgc aactgcgccg cgagcatttc
     4321 ggctttattt tccagcgtta ccatttgctt tcgcatttaa ccgccgagca gaacgttgaa
     4381 gtacccgccg tctatgccgg tcttgagtgg aaacagcggc tgcttcgcgc ccaggagtta
     4441 ctgcaacgac tggggctgga agaccgtaca gagtattacc cggcacagct ttcgggtggc
     4501 cagcaacagc gcgtcagtat cgcgcgggca ttgatgaacg gcggtcaggt aattcttgcc
     4561 gatgaaccga ccggcgcact ggacagccat tctggcgaag aggtgatggc gatcctgcat
     4621 cagctgcgcg atcgcgggca tacggtgatt atcgtcacac acgatccgca ggttgctgct
     4681 caggccgagc gggtgatcga aattcgcgac ggcgaaattg tgcgcaatcc tcccgccatt
     4741 gaaaaagtga atgctactgg cggaacggaa cctgttgtca acacggcgtc tggctggcgg
     4801 cagtttgtca gcggttttaa cgaggcgctg acgatggcat ggcgggcgct ggcagcgaat
     4861 aaaatgcgta ctttactgac catgctgggg attattatcg gtattgcgtc ggtggtttcc
     4921 attgtcgtgg tgggcgacgc cgccaaacaa atggtgctgg cggatattcg ttctattggt
     4981 acgaatacta ttgatgtcta tcccgggaaa gattttggcg atgacgatcc gcaatatcag
     5041 caggcgctga agtacgacga cttaatcgcc atccaaaaac aaccgtgggt cgcctcagcc
     5101 acacctgccg tctcgcaaaa cctgcgcctg cgttataaca atgttgatgt ggctgccagt
     5161 gccaatggcg tgagcggcga ttattttaat gtctatggca tgactttcag tgaagggaac
     5221 acctttaatc aggagcagct gaacggtcgt gcgcaggtcg tggttctcga cagtaatact
     5281 cgccgccagc ttttccccca taaagcagat gtggttggcg aggtgattct ggttggcaat
     5341 atgcccgcca gagtcattgg tgtggcggaa gaaaaacagt cgatgtttgg tagcagtaaa
     5401 gtgctgcgtg tctggctgcc atacagcacg atgtccgggc gagttatggg tcagtcgtgg
     5461 ctgaactcca taactgtcag ggtgaaagaa ggctttgaca gcgctgaggc ggaacagcaa
     5521 ctcacgcgtt tactttcact gcgccacggt aagaaggatt tctttacctg gaacatggat
     5581 ggcgtcttga aaaccgttga aaagaccaca cgtactttac aactgtttct gacgctggtg
     5641 gcggtgattt cgctggtggt gggcggtatt ggtgtaatga atattatgct ggtgtcagtg
     5701 accgagcgga cgcgggaaat tggcattcgc atggctgtag gtgcgcgagc aagcgatgtt
     5761 ttgcaacagt ttctgatcga agccgtactg gtttgcctgg ttggtggcgc tttgggaata
     5821 acactgtcac tgttaattgc tttcaccttg cagcttttct tacccggctg ggagattggt
     5881 ttttcaccgt tagcgctgct gctggcgttt ctctgctcga cggtcaccgg gattttattt
     5941 ggctggttac ccgcacgaaa tgcggcacga ctggatccag tagatgctct ggcacgggag
     6001 taatttttga gataaaaatg ccagccgatc gggctggcat tttgccttta ggatgtacac
     6061 aatgagacag aagagctatg cgactgccgc ttctacttcg acgggcacaa taacactggc
     6121 gtgattgcct tttggcccct ggtggacatc aaactgaacg gattgtccag cttttagcgt
     6181 tctgtaacca tccatctgaa tggtggaata atgagcgaaa atatcttcgc cgccgccttc
     6241 agggcagatg aaaccaaacc ctttggcatt gttgaaccac ttaacagtac ccttttccat
     6301 gcttcgacat ccttcgcaaa tcttatacaa gtaagatgga ataaaccggg gtcagagagg
     6361 gggctgttca aaacctcgcc aactctagaa atacaattta gagaattagg gcgagccgtc
     6421 aagcatttga caggggccag ggggcaggta tgaatcaaaa atttgaagca gttaacgcta
     6481 ttgacaggaa tgtgacagat gtcgctgatg ccaacgatag atgatagtta tctatcatgt
     6541 ggagtagatt ggtcaggcaa ataagctctt gtcagcggca gggcgttctg ccgataaccg
     6601 taaccgaaga tgataactga caatgggtaa aacgaacgac tggctggact ttgatcaact
     6661 ggcggaagaa aaagttcgcg acgcgctaaa accgccatct atgtataaag tgatattagt
     6721 caatgatgat tatactccga tggagtttgt tattgacgtg ttacaaaaat tcttttctta
     6781 tgatgtagaa cgtgcaacgc aattgatgct cgctgttcac taccagggga aggccatttg
     6841 cggagtcttt accgctgagg ttgcagaaac caaagtggcg atggtgaaca agtacgcgag
     6901 ggagaatgag catccattgc tgtgtacgct agaaaaagcc tgaatgcagg cataaaaatt
     6961 gggggaggtg cctatgctca atcaagaact ggaactcagt ttaaatatgg ctttcgccag
     7021 agcgcgcgag caccgtcatg agtttatgac cgtcgagcac ttgttactgg cgctgctcag
     7081 taacccatct gcccgggagg cgctggaagc gtgttctgta gatttggttg cgctccgtca
     7141 ggaactggaa gcctttattg aacaaaccac acccgttctg cctgccagtg aagaggagcg
     7201 cgacacacag ccgacgttga gttttcagcg tgtactgcaa cgtgcggtct tccatgtcca
     7261 gtcctccggt cgcaatgagg ttaccggtgc aaacgttctg gtcgctatct ttagcgaaca
     7321 ggagtcgcag gcggcatatc tgttgcgcaa acatgaagtc agccgtctcg atgtggtgaa
     7381 ctttatctct catggcacgc gtaaagacga gccgacacag tcttctgatc ctggcagcca
     7441 gccaaacagc gaagaacaag ctggtgggga ggaacgtatg gagaatttca cgacgaacct
     7501 gaatcagctt gcgcgagtgg gcggaatcga cccactaatt ggtcgtgaga aggagctgga
     7561 gcgtgctatt caggttctct gccgtcgccg taaaaacaac ccgctgctgg tgggggagtc
     7621 tggtgtcggt aaaaccgcga ttgcggaggg gcttgcatgg cgaattgttc agggcgatgt
     7681 gccggaagtg atggctgact gtacgattta ctctctcgat atcggttccc tgttagcggg
     7741 cacaaaatat cgcggcgact ttgaaaaacg ttttaaagcg ttgctcaagc agctggagca
     7801 ggacactaac agcatcctgt ttattgatga gatccacacc attatcggtg cgggtgcagc
     7861 gtctggtggc caggtcgatg cggctaacct gattaaaccg ttgctctcca gcggtaaaat
     7921 ccgcgtaatt ggttcgacaa cctatcagga gttcagcaac attttcgaga aagaccgtgc
     7981 tctggcgcgt cgcttccaga aaattgatat tactgaaccg tcaatcgaag aaactgttca
     8041 aatcatcaat ggcctgaaac cgaagtatga agcgcaccac gacgtgcgtt ataccgcaaa
     8101 agcggtgcgt gcggcggtag agctggcggt gaaatacatt aacgatcgtc atctgccgga
     8161 taaagcgatt gatgttatcg acgaagcggg cgctcgcgca cgtctgatgc cggtaagcaa
     8221 acgcaagaaa accgttaatg tggcggatat tgaatccgtg gtggcccgta ttgcacgcat
     8281 tccagagaag agtgtttctc agagtgaccg cgataccctg aaaaacctcg gcgatcgcct
     8341 gaaaatgctg gtcttcggtc aggataaagc cattgaggcg ctgactgaag ccattaagat
     8401 ggcgcgtgca ggtttaggtc acgaacataa accggtcggt tcgttcctgt ttgccggccc
     8461 tactggggtc gggaaaacag aggtgacggt acagctttcg aaagcgttgg gcattgagct
     8521 tctgcgcttt gatatgtccg agtatatgga acgccatacc gtcagccgtc tgattggtgc
     8581 gcctccggga tacgttggtt ttgatcaggg cggtttgctg actgatgcgg tcatcaagca
     8641 tccacatgcg gtgctgctgc tggacgaaat cgagaaagcg cacccggacg tgttcaatat
     8701 tctgttgcag gtgatggata acggtacgct gaccgataac aacggacgca aagcggactt
     8761 ccgtaacgtg gtgctggtga tgaccactaa tgccggggta cgggaaactg agcgcaaatc
     8821 cattggtctt atccaccagg ataacagcac cgatgcgatg gaagagatca agaagatctt
     8881 tacaccggaa ttccgtaacc gtctcgacaa cattatctgg ttcgatcatc tgtcaaccga
     8941 cgtgatccat caggtggtgg ataaattcat cgtcgagttg caggttcagt tggatcagaa
     9001 aggtgtttct ctggaagtga gccaggaagc gcgtaactgg ctggccgaga aaggttacga
     9061 ccgggcaatg ggcgcacgtc cgatggcgcg tgtcatccag gacaacctga aaaaaccgct
     9121 cgccaacgaa ctgctgtttg gttcgctggt ggacggcggt caggtcaccg tcgcgctgga
     9181 taaagagaaa aatgagctga cttacggatt ccagagtgca caaaagcaca aggcggaagc
     9241 agcgcattaa tctgattgtc tggtaggttg gtgaagtccg taatctcgtc aggggttacg
     9301 gactttttat ttatgggggg aggaggttca gacccttttt ttgatgatga tggtaagtta
     9361 ttgataatta gtgctgcggg taggtaagga taaaaaaggg tggcagcagg agattgagat
     9421 ggttttgctt tattaacaac gggctaaacg tgtagtattt gagttcactg ccgtacaggc
     9481 agcttagaaa ttgccgcgga tcctgtctgc caataatgac aagttcactg ccgtacaggc
     9541 agataaaatg cgaaaaaaaa gcccgtactt tcgtacgagc tcttctttaa atatggcggt
     9601 gaggggggga ttcgaacccc cgatacgttg ccgtatacac actttccagg cgtgctcctt
     9661 cagccactcg gacacctcac caaattgttt ttttgcctga cctcatgggg ggcaacgggg
     9721 cgctactata gggagttgga ataaaacggt caagaagaat ttttatgata attattgttt
     9781 gctcatactg taaacaagtt gtgcagtata tctacatcga gacaagttac ggacttatac
     9841 ttctaaagta ctccatacat atcacaaaat aaaaaggccg gctaaaccga ccttttactc
     9901 attctttctc ttcgcccatc aggcggtaaa acaatcagcg actacggaag acaatgcggc
     9961 ctttgctcag gtcgtacggg gtcagttcaa cagtcacttt gtcgcccgtc aggatgcgga
    10021 tgtagttttt gcgcatttta ccggagatgt gtgcagtaac cacgtgaccg ttttctaact
    10081 ctacgcggaa catggtatta ggcaacgttt caagaacggt accttgcatt tcaatattgt
    10141 cttctttggc catctaatcc tctggggtat cactaccgta atttgaaccg gcaagataat
    10201 gccgaagttc tgtaaataag taaagatttg cgcgctaaat cgcaacaaac aggttcggca
    10261 cattactccg aaaacacacg gctaagccgc accaaaagcg caacgtataa gggagcggtg
    10321 agataaacga tgggcgttac ctgacgcgaa aaattcctta tcggcagcgg ggtaatgagc
    10381 gtaaccaact ctgcgaccgc aattataaca ctctggggag aaatgtgccg aaaacattca
    10441 ttcttgtggt gaaaacaagc atcgaggtac ccagaaatta ttcgacaatc gtccgaggcg
    10501 catttgattg agataattaa ggtaatcccg gcggggaatt tcgcaggcac caagcgatgc
    10561 tgtgtgatcg ttaaggacct ggcagtcgat aagtttaccg ccatgacgga taaattcatc
    10621 acagaagacc agaagcgccg ttttggacgc attttccatc cggctgaaca tggactcgcc
    10681 acaaaatagt gttccctggg ccacgccgta cataccgccg acaagctcat cttcacgcca
    10741 gacttcaatg gagtgggcat gaccgagttc gtgaaggcga tggtaggctt cgaccacgcc
    10801 acgcgtgatc caggttcctt cttcgcgatc gctggcacag ccttcgatga cctgaccaaa
    10861 agcgtaattc atcgtgacac gatagggtga gcgtttatga aatcgcttca tactacggct
    10921 gatatgcagt gattctggcc ataacaccgc gcggggatcg ggcgaccacc agaggatggg
    10981 gtcgccagga gaaaaccacg ggaaaatacc acgctgataa gccattaata ggcgcgcagg
    11041 gctaagatcg ccccccagtg ccagcaggcc gttaggctca cgtaatgcgc cttccgggga
    11101 agggaaggct attgaatggc gagaaagctg aaccaggcgc atgaccgcaa aactccacgc
    11161 aagtcggatc gttcaataat agcttacaaa ccctgcttaa actggtaata acgcccctgt
    11221 ctggcaagca gttctgcgtg agtaccttgc tcaataattt gcccgttgtc catcactatt
    11281 atttgttgga aacgagagag cccgcgaagt cgatgggtga ccattaacac cgttttctcg
    11341 cacatcattt ctgcaagcaa ttcaaggatc tgactttcgg ttgtggcatc taagccttct
    11401 gtaggttcat ccagcaatac cagcggcgca tcatgtaaca gcgcacgggc gatagccaga
    11461 cggcgcagtt caccaccgga gagctggcgt ccgccttcac ctaaccaact gttgagacct
    11521 gcatcctcga gcagcttctc cagaccaacg cgacgcaaga tctccgccag agcctcatca
    11581 ctactaccag gcgaggcgag taacagatta tcacgcagcg tggcgctaaa cagatgcact
    11641 cgctggggaa caacgctgat ggtctgtcgt agagccgctt cattcaggct ggctatggga
    11701 ctatcgttaa gcaaaatctc gccctgttgc gggtcccatg cgcgggtcag cagttgtaac
    11761 agtgttgact tgccgcatcc ggttcgcccg agaatcgcaa tatgttcccc ggcgtttacc
    11821 tgaagataaa tccctttaag tgcctgttgg gattgctccg gataagtgaa ctgaacatcc
    11881 cgtaatgtca gcgaaacgcg atcggcaaca cgagtttggg tatcagggaa ggtgactttc
    11941 ggtttttgat ccgttaaatc agtgatccgt acggcagagg caatgacttg ccccagatgc
    12001 tgaaatgcac ccgttactgg tgccagcgct tcaaacgcgg ctaacgcgca gaagacaaac
    12061 agggcaatta acgcgccggg ttgagcattg ccgccaacgc cgccagacgc catccacagc
    12121 atcaggatca ccgctaacgc gccaatgagc agcattatcg cttgcgacaa tgcggttagt
    12181 tcagattgac ggcgttgcgc ttccagccat tgaatttctg tattctctaa ttgcgtgcga
    12241 taacgatcgc tggcaccaaa aatggtcagc tcagcttgcc cttgcagcca ggccgtcagt
    12301 tgttggcgat actgcccgcg aagatgagtc agattttgcc cggtgctttt tcccgcacga
    12361 taaaacagtg gtggcatcag gaaaagcgtc agtaacataa tgccgcccag cgtaaaggcg
    12421 agggtgaaat caaggaaact taacccgatt gtcaccacca taatcaccac aaaagcgcct
    12481 accagcggcg agataacgcg caggtaaaga tgatcgagcg tatcaacatc cgccaccacg
    12541 cggttgagta attcgccctg acgatagcgc gccagtcctg caggggagag gggcagtaat
    12601 ttgctgaagg tgtaaatgcg cagatgctgc aacacgcgga aagtcgcatc gtgacttacc
    12661 aggcgttcaa aatagcgccc ggcagtacgg gtgattgctg cgccacgcac gcccgcagcg
    12721 ggtagcatat agttgaagct gtacagtccg gcaacccccg caaccgctga ggcggagagg
    12781 aaccagcccg aaagtgtcaa cagaccgata ctggcgagca gcgtgacaat tgccagcacg
    12841 ataccaagac ttaacatcca tttatgacgt ttatacagtg ccagataggg tagcaaagcg
    12901 cgcatttaaa tctcctcctg acgatgggcc agtaatgtgg cgaatgggcc accagccaca
    12961 cttaattccg cgtaacgtcc ttgctcaata atctgaccat cctgcattac ccaaatgaca
    13021 tcccagtcag caagatcttc taactggtgg gtgaccatta acgttgtctg gcgcagagag
    13081 gcggcattca gcgcctccat tacgcgctgt tcactgtgag catcaaggct ggcagcgggt
    13141 tcatccaaca gtaatagcga acagggattt agtaacgcac gggccaccgc cacgcgctgc
    13201 gcctgcccca cggaaaggcg ggcagcctgg tcgccaacag gcgtatcaac gccttgtggc
    13261 aggagcggta gaaactcact gacccaggcg ttatccagcg ctgtttgtaa ctcttgttcg
    13321 ctggcatcag gtcgcgccag tagtacgtta tcccgtaatg ttgctgccgg taattgtggg
    13381 ttttgcccaa cccaggagag atgtttacgc catgattccg gtgataaatc gcgtaattct
    13441 atcccgttga ttcgtagcga tccctgatat gagagaaaac cagaaagcgc gttcaacagt
    13501 gaacttttac ctgaaccgct gcgaccaacc aacactgctc gttggcctgc tggcaaagta
    13561 aaattcagcg gtccggccag cgttttacct tccggcgacg tgataaacag atcctcggct
    13621 tcaatggtca ccggatcggt cgatgctaat tccgcttcac cgcgctgcgg atgggctagc
    13681 ggggtttcca taaacgtttt caaactgtca gctgcaccaa cagcctgggc tttagcatga
    13741 taaaacgtac cgagatcgcg taatggctgg aaaaactctg gcgcaaggat cagggccaga
    13801 aaacccgcag ccagcgtcac gccagtatcg tagtgaccaa aatccagctc gccgaggtag
    13861 gaaaaaccaa agtagaccgc caccagagca atcgacagcg aggtaaaaaa ttcgagaatg
    13921 ccggaggata aaaacgccag ccgtagcact tccattgtcc gttggcggaa atcttccgaa
    13981 gcagaacgaa tactttcaat ttcagcttca ccacgaccaa aaatacgcaa tgtttccatg
    14041 ccgcgcaggc gatcgaggaa atgcccactt aagcgagcaa gagcgagaaa gttacgtcgg
    14101 ttagcatcgg cagcccccat tccaaccagc gccataaata acggaattag cggtgcagtg
    14161 cccagcagaa tgagcgccgc ggcccagtta gaggggaaga tagccaccac aatcagcagc
    14221 ggcaccgaca ctgccagcgc catttgcggc aggtagcgtg catagtaatc atgcatatcg
    14281 tcaatttgct cgagtaccag cgtcgcccag ctccccgcag gtttaccctg aatccacgct
    14341 ggccctgctt gttgcagacg gtcgagaacc tgacggcgga tggcaaagcg gatatgctgc
    14401 ccggcgtgat aacccacccg ttcgcgtaac cagaccaccc atgcgcgcag tacaaaggtc
    14461 agaaacagta acgtaaaggg aagcagcagg gcttcacggg gaatattctc cataatcata
    14521 tgttgcagaa ttcgcgccat gaaccaggcc tgggcaatga tcaatatgcc gctcacaaag
    14581 cccagcagac gagaaatatt cagccaacgt tgggagatga cgctttgctg ttttaaccag
    14641 cgggttaatt ctttttgacg ggatttattc attgcacgct tagcaggtga gttatcagaa
    14701 ttatttgcag agcaatgtta caacggggaa aaaataaagg cgacccatag tcgcatggtg
    14761 tcgccttctt tacttttgtt actgatttgt aaaattattt tgcgtcagct aaaccgtcga
    14821 ggtagcgttc cgcatcaaga gctgccatgc agcctgtacc agcagatgta atggcctggc
    14881 gataaatgtg atccatcacg tcgcctgcgg caaagacgcc agggatgctg gtctgggtgg
    14941 cattaccatg aatacccgac tgtactttga tgtagccgtt ttccagttcc agctgccctt
    15001 cgaaaatggc agtattcggg ctgtgaccga tagcaacaaa cagaccggca acgtcgagtg
    15061 actcgatatt atcggtgttt tgcgtatcgc gcagacgaac gccagtgacg cccatctgat
    15121 cgccggtcac ttcttccagc gtacggttgg tgtgcagaat aatgttgccg ttctccactt
    15181 tatccatcag acgcttaatg aggatttttt ccgcacggaa accatcacgg cggtgaatca
    15241 gatgaacttc cgaagcgatg ttagacagat acagcgcctc ttcaaccgcg gtattgccgc
    15301 cgccgatgac cgcaactttc tggttgcgat agaagaaacc gtcgcaggtt gcacaagcag
    15361 aaactccacg gcctttaaag gcttcttcag agggcaggcc gagatagcgt gcagaagctc
    15421 cggtggcaat aatcagcgcg tcgcaagtgt attcgccgct atcgccagtc agacggaacg
    15481 gacgattctg caaatcaact ttgttgatgt gatcaaagat gatttcagtt tcaaatttgg
    15541 tggcatgttc gtgcatgcgc tccattaata acggaccggt cagatcgttt ggatcgccag
    15601 gccagttttc cacttccgtg gtggtggtca gttggccgcc tttttccatg ccggtaatca
    15661 gcacaggttg caggttggcg cgcgccgcgt agacagcagc ggtgtatccc gccgggcctg
    15721 aacccaggat aagcagttta ctgtgtttgg tcgtgcccat gagatcccca tagttgttgg
    15781 cagacaatgg caggattgta gggaatttac agacgtaaaa aaagagtatg acgattttgt
    15841 taacaatttg tgcaatcggc agcatcgata agcaggtcaa attctcacgt cattatcacc
    15901 tctgctactt aaatttcccg ctttataagc cgattaaatg atgaataaac gcccctgtta
    15961 atgaatatct ggcatgttgt actaaaaatc gatgttttgc tttgacaatc ccctggtgtt
    16021 ttgcgaaaac attcgaggaa gaaaaaaaac agtattctta tatgcgcata accatgcatg
    16081 taaataccat gtttaccgtg ctagtgaaat ctacgtatgg cgtggacaga cgccattcgt
    16141 gatgtcgata gctgccacaa ggcaacggtc ttctcaccgt agacccaggc attgcgcgcc
    16201 gtgaatcttc atgatttcgg tctatcgtga cgggtagcga ctctgaacag tgatgtttca
    16261 gggtcagaca ggagtaggga aggaatacag agagacaata ataatggtag atagcaagaa
    16321 gcgccctggc aaagatctcg accgtatcga tcgtaacatt cttaatgagt tgcaaaagga
    16381 tgggcgtatt tctaacgtcg agctttctaa acgtgtggga ctttccccaa cgccgtgcct
    16441 tgagcgtgtg cgtcggctgg aaagacaagg gtttattcag ggctatacgg cgctgctgaa
    16501 cccccattat ctggatgcat cacttctggt attcgttgag attactctga atcgtggcgc
    16561 accggatgtg tttgaacaat tcaataccgc tgtacaaaaa cttgaagaaa ttcaggagtg
    16621 tcatttagta tccggtgatt tcgactacct gttgaaaaca cgcgtgccgg atatgtctgc
    16681 ttaccgtaag ttactggggg aaaccctgct gcgtctgcct ggcgtcaatg acacacggac
    16741 atacgttgtt atggaagaag tcaagcagag taatcgtctg gttattaaga cgcgctaaca
    16801 cggaacaggt gcaaaatcgg cgtattttga ttacactcct gttaatccat acagcaacag
    16861 tactggggta acctggtact gttgtccgtt ttagcatcgg gcaggaaaag cctgtaacct
    16921 ggagagcctt tcttgagcca ggaatacact gaagacaaag aagtcacatt gacaaagtta
    16981 agtagcggcc gccgccttct ggaggcgttg ctgatcctta ttgtcctgtt tgccgtctgg
    17041 ttgatggctg ccttactaag ctttaaccct tcggacccca gctggtcgca aacggcctgg
    17101 catgaaccta tccataattt aggtgggatg cccggtgcgt ggctggcaga tacgctgttc
    17161 tttatttttg gcgtgatggc ttacaccatt cccgtcatta ttgtcggcgg ttgttggttt
    17221 gcctggcgtc atcagtccag cgacgaatac attgattatt ttgccgtttc gctacgcatc
    17281 attggcgttt tggcgctcat ccttacctcc tgtggtctgg cggcaatcaa cgctgacgat
    17341 atctggtatt ttgcctccgg tggcgtcatt ggcagcttac taagcactac gctacaacca
    17401 ctgctacaca gtagcggggg aactattgcg ctgctctgcg tttgggcagc gggcctgacg
    17461 ctgttcaccg gttggtcatg ggtgaccatt gctgaaaaac tcggcggctg gattttaaat
    17521 attcttacct tcgccagtaa tcgtacccgt cgcgatgata cctgggtcga tgaagatgag
    17581 tatgaagacg acgaagagta tgaagatgaa aatcacggca aacagcatga atcacgccgt
    17641 gcccgtattc ttcgcggcgc gctagcgcgt cgtaaacggt tggcggaaaa attcattaat
    17701 ccgatggggc ggcaaacaga cgctgcgttg ttctccggta agcggatgga tgatgacgaa
    17761 gagattacct acactgcacg cggtgtggct gccgaccctg acgacgtcct cttttcgggc
    17821 aatcgtgcaa cgcagccaga atatgacgag tacgatccat tattaaacgg tgcgccaatt
    17881 accgaacctg ttgctgtagc agctgctgct accacggcga cacaaagctg ggctgcaccg
    17941 gttgaacctg tgactcagac gccgccagtt gcctctgttg atgttccacc tgcgcaatct
    18001 acagtagcct ggcagcctgt accggggccg caaacgggag aaccggttat tgctcctgca
    18061 ccggaaggtt acccacagca gccacaatat gcgcagcctg cagtgcaata taatgagccg
    18121 ctgcaacaac cagtacagcc acagcagccg tattatgcac ctgcagctga acaacctgcg
    18181 caacaacctt actacgctcc tgcggcggaa caacctgttc agcaaccgta ttacgcaact
    18241 gcggcggaac agcctgcgca acagccgtat tacgcccctg cgccagaaca agcggtggca
    18301 ggtaacgcct ggcaagccga agagcagcaa tccacttttg ctccacagtc tacataccag
    18361 actgagcaaa cttatcagca gccagccgct caggaaccgt tgtaccaaca gccgcaacct
    18421 gttgaacagc agcctgttgt ggagcctgaa cccgttgtag aagagacaaa acccacgcgt
    18481 ccgccgcttt actactttga agaagtggaa gagaagcgag cccgtgaacg cgaacaactt
    18541 gcggcctggt atcaaccgat tccagaacct gttaaagaac cagaaccgat caaatcttcg
    18601 ctaaaagcac cttctgttgc agcagtacct ccagtggaag ccgctgccgc cgtttctccg
    18661 ctggcatctg gcgtgaaaaa agcgacactg gcgacggggg ctgccgcaac cgttgccgcg
    18721 ccagtcttca gtctggcaaa tagcggtgga ccgcgtccgc aggtcaaaga ggggattggc
    18781 ccgcagttgc cacgaccgaa acgcatccgc gtgccaactc gtcgtgaact ggcgtcttac
    18841 ggtattaagc tgccctcaca gcgtgcggca gaagaaaaag cccgtgaagc ccagcgtaat
    18901 cagtacgatt ctggcgatca gtacaacgat gatgaaatcg atgcgatgca gcaggatgaa
    18961 ctggcacgtc agttcgccca gacgcagcag caacgctatg gcgaacagta tcaacatgat
    19021 gtgcccgtga acacagaaga tgcagatgct gcggcagagg cagaactggc tcgtcagttt
    19081 gctcaaactc aacaacaacg ttattccggc gaacaaccgg ctggggcgaa tccgttctcg
    19141 ctggatgatt ttgaattttc gccaatgaaa gcgttgctgg atgatggtcc acacgaaccg
    19201 ctgtttacgc caattgttga acctgtacag cagccgcaac aaccggtagc accgcagcag
    19261 caatatcagc agccgcaaca accggttgca ccgcagccgc agtatcagca gccgcaacaa
    19321 ccggttgcac cgcagcagca atatcagcag ccacaacaac cggttgcaca gcagccgcag
    19381 tatcagcagc cacaacagcc ggttacacag cagccgcagt atcagcagcc gcagcagccg
    19441 gttgtaccac agccgcaata tcagcagccg caacagccag ttgcgccaca gccgcaggat
    19501 accctgcttc atccgctgtt gatgcgtaat ggcgacagcc gtccgttgca taaaccgacg
    19561 acgccactgc cttctctgga tttgctgaca ccgccgccga gcgaagtgga gccggtagat
    19621 acctttgcgc ttgaacaaat ggcgcgcctg gtagaagcgc gtctggctga tttccgtatt
    19681 aaagccgatg ttgtcaatta ctctccgggg ccagttatca ctcgctttga attgaacctg
    19741 gcaccgggcg taaaagcggc gcgcatttct aacttgtcac gtgaccttgc ccgttcactt
    19801 tcgacggtgg cggtgcgtgt cgttgaagtt attcctggca aaccctatgt aggtctggag
    19861 ttaccgaata aaaaacgaca aaccgtttat ctgcgcgagg ttttggataa cgccaaattc
    19921 cgcgataatc cgtcgccatt aaccgtggtg ctgggtaaag atatcgccgg tgagccggtg
    19981 gttgccgatc tggcgaaaat gccgcacttg ttggttgcgg ggactaccgg ttccggtaag
    20041 tctgtcgggg tgaacgcgat gatcctgagc atgctttata aagcacagcc agaagatgtg
    20101 cgtttcatca tgatcgaccc gaaaatgctg gagctttcgg tttatgaagg cattccgcac
    20161 ctgttaacgg aagttgttac tgatatgaaa gatgccgcca acgcgctgcg ctggtgtgtt
    20221 aacgagatgg agcgtcgtta taaactgatg tctgcgctgg gtgtgcgtaa tctggcgggt
    20281 tataacgaaa aaattgctga agccgatcgc atgatgcgtc cgattccaga cccgtactgg
    20341 aagccgggtg atagtatgga tgcgcagcat ccggtgctga aaaaagaacc gtacatagtg
    20401 gtgttggtgg acgaatttgc cgacctgatg atgacggtag gtaaaaaagt ggaagagctg
    20461 atagcacgtc tggcgcaaaa agctcgtgcc gcgggtatcc acctcgtact ggcaacgcag
    20521 cgtccatcgg ttgatgttat tactggtctg attaaagcga atattccgac ccgtatcgcc
    20581 tttaccgtat ccagtaagat tgactcacgt accattcttg atcaggctgg tgcggaatca
    20641 ctgctgggta tgggggatat gctctactct gggccgaact ccactttgcc ggtacgtgtc
    20701 catggtgctt ttgttcgcga tcaagaagtt catgccgtgg tgcaggactg gaaagcgcgt
    20761 ggtcgcccac agtatgttga tggcatcacc tccgacagcg aaagcgaagg tggcgcgggc
    20821 ggtttcgatg gcgctgaaga gctggatccg ttgttcgatc aggcggtgca gtttgtcact
    20881 gaaaaacgca aagcatcaat ttctggcgta cagcgtcagt tccgcattgg ttataaccgt
    20941 gcagcgcgta ttatcgaaca gatggaagcg caggggattg tcagcgaaca ggggcacaac
    21001 ggtaatcgtg aagtgctggc cccaccgccg tttgactaat taatgcatcg taggccggat
    21061 aaggcgcggt agcgtcgcat ccggcaatct ggtaactgaa aattcagtat tttcttcttt
    21121 cctcaagctg attattagcc tggaatagag agtagaggga gctcccggtc gggagtgacg
    21181 taatttgagg aataatgatg aaaaaaattg ccatcacctg tgcattactc tcaagcttag
    21241 tagcaagcag cgtttgggct gatgccgcaa gcgatctgaa aagccgcctg gataaagtca
    21301 gcagcttcca cgccagcttc acacaaaaag tgactgacgg tagcggcgcg gcggtgcagg
    21361 aaggtcaggg cgatctgtgg gtgaaacgtc caaacttatt caactggcat atgactcaac
    21421 ctgatgaaag cattctggtt tctgacggta aaacactgtg gttctataac ccgttcgttg
    21481 agcaagctac ggcaacctgg ctgaaagatg ccaccggtaa tacgccgttt atgctgattg
    21541 cccgcaacca gtccagcgac tggcagcagt acaatatcaa acagaatggc gatgactttg
    21601 ttctgacgcc gaaagccagc aatggcaatc tgaagcagtt caccattaac gtgggacgtg
    21661 atggcacaat ccatcagttt agcgcggtgg agcaggacga tcagcgcagc agttatcagc
    21721 tgaaatccca gcaaaatggg gctgtggatg cagcgaaatt taccttcacc ccgccgcaag
    21781 gcgtcacggt agatgatcaa cgtaagtaga ggcacctgag tgagcaatct gtcgctcgat
    21841 ttttcggata atacttttca acccctggcc gcgcgtatgc ggccagaaaa tttagcacag
    21901 tatatcggcc agcaacattt gctggctgtg gggaagccgt tgccgcgcgc tatcgaagcc
    21961 gggcatctgc attctatgat cctctggggg ccgccgggta ccggcaaaac aaccctcgct
    22021 gaagtgattg cccgctatgc gaacgctgat gtggaacgta tttctgccgt cacctctggc
    22081 gtgaaagaga ttcgcgaggc gatcgaacgc gctcggcaaa accgcaatgc aggtcgccgc
    22141 actattcttt ttgttgacga agttcaccgt ttcaacaaaa gccagcagga tgcatttctg
    22201 ccacatattg aagacggcac catcactttt attggcgcaa ccactgaaaa cccgtcgttt
    22261 gagcttaatt cggcactgct ttcccgtgcc cgtgtctatc tgttgaaatc cctgagtaca
    22321 gaggatattg agcaagtact aactcaggcg atggaagaca aaacccgtgg ctatggtggt
    22381 caggatattg ttctgccaga tgaaacacga cgcgccattg ctgaactggt gaatggcgac
    22441 gcgcgccggg cgttaaatac gctggaaatg atggcggata tggccgaagt cgatgatagc
    22501 ggtaagcggg tcctgaagcc tgaattactg accgaaatcg ccggtgaacg tagcgcccgc
    22561 tttgataaca aaggcgatcg cttttacgat ctgatttccg cattgcataa gtcggtacgt
    22621 ggtagcgcac ccgatgcggc gctctactgg tatgcgcgaa ttattaccgc cggtggcgat
    22681 ccgttatatg ttgcgcgtcg ttgcctggca attgcttccg aagatgtcgg caatgccgac
    22741 ccacgggcga tgcaggtggc aattgcggcc tgggattgct ttactcgcgt tggcccggcg
    22801 gaaggtgaac gcgccattgc tcaggcgatt gtttacctgg cctgcgcgcc aaaaagcaac
    22861 gctgtctaca ctgcgtttaa agccgcgctg gccgatgctc gcgaacgtcc ggattatgac
    22921 gtgccggttc atttgcgtaa tgcgccgacg aaattaatga aggaaatggg ctacgggcag
    22981 gaatatcgtt acgctcatga tgaagcaaac gcttatgctg ccggtgaggt ttacttcccg
    23041 ccggaaatag cacaaacacg ctattatttc ccgacaaaca ggggccttga aggcaagatt
    23101 ggcgaaaagc tcgcctggct ggctgaacag gatcaaaata gccccataaa acgctaccgt
    23161 taatgttatc gttgcggtaa tgttgttaat gtatccctgt ggtcgcaggc tgtggccaca
    23221 tctcccattt aattcgataa gcacaggata agcatgctcg atcccaatct gctgcgtaat
    23281 gagccagacg cagtcgctga aaaactggca cgccggggct ttaagctgga tgtagataag
    23341 ctgggcgctc ttgaggagcg tcgtaaagta ttgcaggtca aaacggaaaa cctgcaagcg
    23401 gagcgtaact cccgatcgaa atccattggc caggcgaaag cgcgcgggga agatatcgag
    23461 cctttacgtc tggaagtgaa caaactgggc gaagagctgg atgcagcaaa agccgagctg
    23521 gatgctttac aggctgaaat tcgcgatatc gcgctaacca tccctaacct gcctgcagat
    23581 gaagtgccgg taggtaaaga cgaaaatgac aacgttgaag tcagtcgctg gggcaccccg
    23641 cgtgagtttg actttgaagt tcgtgaccat gtgacgctgg gtgaaatgca ctctggcctc
    23701 gactttgcag ccgcagttaa gttgactggt tcccgctttg tggtaatgaa agggcagatt
    23761 gctcgcatgc accgcgcact gtcgcagttt atgctggatc tgcataccga acagcatggc
    23821 tacagtgaga actatgttcc gtacctggtt aaccaggaca cgctgtacgg tacgggtcag
    23881 ctgccgaaat ttgctggcga tctgttccat actcgtccgc tggaagaaga agcagacacc
    23941 agtaactatg cgctgatccc aacggcagaa gttccgctga ccaacctggt acgcggtgaa
    24001 atcatcgatg aagatgatct gccaattaag atgaccgccc acaccccatg tttccgttct
    24061 gaagctggtt catatggtcg tgacactcgt ggtctgatcc gtatgcacca gttcgacaaa
    24121 gttgaaatgg tgcagatcgt gcgcccggaa gactcaatgg cggcgctgga agagatgacc
    24181 ggtcatgcgg aaaaagtcct gcagctgctg ggcctgccgt accgtaaaat catcctttgt
    24241 accggcgaca tgggctttgg cgcttgcaaa acttatgacc tggaagtatg gatcccggca
    24301 cagaacacct accgcgagat ctcttcctgc tccaacgttt gggatttcca ggcacgtcgt
    24361 atgcaggcac gttgccgcag caagtcggac aagaaaaccc gtctggttca taccctgaac
    24421 ggttctggtc ttgctgttgg tcgtacgctt gttgcagtaa tggaaaacta tcagcaggct
    24481 gatggtcgta ttgaagtacc agaagttctg cgtccgtata tgaatggact ggaatatatt
    24541 ggctaatacc caatttttct gaatctaaaa agcgcctgcg ggcgctttaa gtagaggttt
    24601 aatcatttga aaataaatgg attttatttt taagtgtcca tataacgtcc atctttgaat
    24661 gcaaaaagcc cacagcttct atgctgtggg ctttgttttt tggtgtcctc atgagtgagg
    24721 gaaccaaaaa gaaaacccgc agtttttacg ctgcgggctt gttgttcacg tcaactggaa
    24781 atagggtgcc ttttcgacct ttaccctggc aaccgattga cggggaagtt gccttccccg
    24841 tcgcggtttc cttactgctt acactgtaag aacgccgcaa actccgctcc ccagaaactc
    24901 atccgtattt cacacagcga accgtgcagc atccagatga tgaggattgc cgtcacgcag
    24961 aatgtgatgg ccgtaagcga tttttgcgac atagcgcttg ctcctttttc ggggaggcgc
    25021 taacctatca cttgctgagg gtagatggtt agggcctcgg gttaacgtta aagttgactc
    25081 ggggcctttc cacatctggc cttcgggtat tccctccgac catcagccga aagacacccg
    25141 cacgtaatct atcgcttttt tgttactccg gcaattctgc ctgttaattc tgagataaag
    25201 gcaaactcat ctgattgttt cccctgtgtg aagctggcag atcatgccac gggatacctt
    25261 ctgaagagtg aacgccggag gcgtgttttg atgtgaattt atggaaagct tccagtgttg
    25321 agaagcatac gccgcattcc agattgttac actggtaata cttttgccgc acggtgtttg
    25381 aatcattttc cggacgactg gtgcggatac gggcagatgc gccacaaagc ggacaacgga
    25441 acatagcgac ctcccttaac gtggtgctgc ctattctaag ttgctcactc tgtttccgct
    25501 atccattccg ggatttttgc ctcaagctca agctgcgtgg taaaaccgct gttatcaatg
    25561 gtgtgctcgg cttttgcaat gatccagtcc tgattatcaa tctcgctttt aaatcctgtt
    25621 accgtgccat gcatttcggg gtagagttct gcacgtccac gcgccagcgt gatggagaat
    25681 gatgcggctc cgcgttgtag ttgctgccac tttgccgccg ctgcgcgtct tgctgcctgc
    25741 tcgttctgat aagtcttgcg taacacaaac acattgcctt ccgcgccttc catataatca
    25801 ccttcgcggc tgctgctttt ctcctttttg ggttttggcg gtttacggcg tttcacgctg
    25861 acttttttct ttttcccgta attaagatca agccagtaag cgcgtacccc cgtatacgct
    25921 tcgcggtcag caatgcggaa ctgatggcga tcgccgctgc tgcgtgtgat ggcaaacgat
    25981 ggcaacggct ggccctgtgc gttcacgcca ccgccgggca tgatgaataa cagattaccg
    26041 ctttttaccg tggtgattgc gcccagcatt tccgccatgc gcgtaaggaa ggacatgtcg
    26101 ctttcttcgg tctggtcggc gtggtcgatt tcgatatcca tcagcatttc gctgatttgc
    26161 ggtttcagac cataccgatg agcgatggcg gataccacac gctcaacggt cacatcatgc
    26221 caggacacct cacgtttaac gttaaattca tcccgaaaat ctgcgcttct ggctgaaaca
    26281 gtcagcctgt ccggcggtcc ttcgtgagcg atttcatcaa caatgtaagt gcctttttct
    26341 gtcagcggtt ctcctttcca gccaatgaga accgtcaggc gcgcgccccg tggcggtagc
    26401 tgcaactgac catccgcatc atccagcgtg atggtgagct ggtccgcctc aaatccccgg
    26461 ttgtcggtca gtgacaggct catcaggcgc tctgccacgc ctgacagcgt tttaccctcc
    26521 gcgagaatat caaaatccgg cattttcacg gggtctgtgc cctgactgag caattgcatg
    26581 gtggtgtcgg tcatctgctc cctccctgtg cggcatggtc gcatgtgcgt gcggaggggg
    26641 ttactgcttt ttgttgtcgc cgtggcggga gaacggcgca ggggtgagat tacgcgcgtg
    26701 gtgggtgatg attgttgccg aatcatttaa cggatacaag gggctgaagc tatgagtgaa
    26761 actcgttttc atggtgcccg tgtcacggaa agtaccgacc tggtaacagc gattaatgat
    26821 gttgattcca gcgttatcgg tatcgtggca acggcggatg atgcggatgc ggagctgttc
    26881 ccgctgaaca agcccacact gctgacccgc gtcaatgacg tgctgggaaa atgcgggact
    26941 acggggacgc tttatcgtgc gcttaaggct atcgcagacc aggtgagcac aaaagtgatc
    27001 gtcgttcgcg tggctgaaca caaagaagaa ggcggtagga cgcaggatca actggttatc
    27061 ggtggttctg aatctgacgg cagctatacg gggatgtatg cgctgcttgt tgcagagcag
    27121 gatgaaagca tcggataccg tccgcgtatt ctggccgcgc cggagctgga cacggaggcg
    27181 gtgacaaaat ccctgtgcgt gattgcgggt aaactgcgcg cgtttgtgta tgccacatgt
    27241 catggttgta acacgatggc tgaggcgatt acctaccgcc agaaattcaa cgaacgtgag
    27301 gtgatgctct tatggcctga cttcatcgcc tacaacccga aaagtggcaa aaacgaaacg
    27361 ttccccgcgc ctgcttatgc gtgcggcctt cgtgcgtaca ttgaccatga gcagggctgg
    27421 cacaaatcgc tgtccaacgt tccggttaaa aatgtgctgg ggatgtcgag gcatgtgttc
    27481 tggtcgttac aggccgaaga cagtgatgcc aacagcctca acaacaaaga aatcacgacc
    27541 attattcgtc gtaacgggtt ccgcttctgg ggcaaccgca caccggaaac gaacgcctac
    27601 atctttgagg tgtatacccg aaccgcacag gtgctggctg attcaattgc ggaagcgcag
    27661 tttgaaacca tcgacagtcc actgacgcct gcgaacgtga aggatgttat cagtgccatc
    27721 agggcaaaat tggattcgct ggttactgcc gggaaactga ttggcgcgga gtgctggtat
    27781 gacgtggtgg ataacggcac cacggattta cgtcaggggc gtgtgcgtat tcgctacaaa
    27841 tatacgcccg ttcccccgct ggaagacatg gagctttacc agacgtttac tgatgaattc
    27901 tttggtcccg catttgcggt gctgggaggt gcctgatggc tgtaccaaaa catcttcgct
    27961 tttttacgtt gtttgtggat ggtgaaaacg aagtgggtaa agtgacatcc gtcacgccgc
    28021 ccaaactgac gcgcaaaacc gacagctatc gtggtggtgg catgatggga gcagtaagta
    28081 ttgatctcgg tctggacgac tccgcgcttg atgcgagctt tgtcatgggg ggagctgttc
    28141 gtgcactgtt ccttaagtat ggcggcacga ttgacggcac gctgctgcgt tttgcgggtg
    28201 aatattacac cgatgcagaa agcgatctgt atgaaatcga gatgcgcggg cgtgtgacgg
    28261 aaattgatat gggggaggcc aaacagggcg aagccacatc acacacttac gctgtcaaaa
    28321 acacctacta caagctgagc gttaacgatc gcccgctgtg ggaaatcgac ctgttgaacc
    28381 acatctaccg gaaggacggc aaggacattg tgcctgaccg cattcgttcc gcgcttgggc
    28441 ttggctgata agtaatatgc aggcggcgca gtgcgtcgcc tctgactgaa aaggagacaa
    28501 ctgatgaaag atatcgatac tgaaacccgg aataacaccg tagcggatga tgtgacgtca
    28561 ggtgaggata tggctgtcga acgtggtgta aaactttccc ggccaattga gcgtggtgcc
    28621 gaaaaaatca catatgtgga gatcaccggg gctattgagc aggcgggatc cctgcgtggt
    28681 ctgtcgctgt ctgatgtgct gaatctgaaa gcggatacca tgttcacgct gttgcctcgc
    28741 gtgacctcgc cacgactgga tgaagtgatg attaaaaaaa tgtcgtcacg cgattttatt
    28801 cagttgtgcg ctgtggctgt aaattttatg agcgagccag actctggcgc gaagagcgtg
    28861 caggagacgg cagcgtaatc accctggtgt gctttgagca catcgaagat ctggtggcgg
    28921 atattgccgc cattttcaac tggtcgcccg ccgaaatctt catgatgacg cccggcgaag
    28981 tggttagctg gcgtgagcgg gcggcacttc gcagcgggaa tgcagataat gaagactctt
    29041 gacatccggg tcgctttcag cgccgttgac aggctgaccc ggcctgccga aaacgcccgc
    29101 cgcctgatgg ggcagtttgg tgactccatt cagcgaacgc agggggcgat caaaaatctc
    29161 gagcgtcagg cgcgttcatt tgagcgcgcc cgcgacgctg tcagtaaagc ggatgcgggt
    29221 atcgtgaaag cacgacgcca gcttaacgcc cttaatcagt tacaacgcac gggtacagtg
    29281 ctcagcgaaa aacaacaaaa gctgatgcag cagttaagca cccggcttga acgcctgaat
    29341 gaatcgcgca cacgggaaat tcagaaaatg cgggagcttg gcggagaact gaaacgccac
    29401 ggcatttccc tgacaggcag cgataacacc atccagcagg ccatcagacg caccgaacaa
    29461 tacaacaacc agcttgaacg cgaacggcag gcgcttgcgc gtgtaacgca ggctcgtgag
    29521 cggtattcgc gcgcgcagga aaccgcggga aaactgaaaa caggtggtgc gctggcaatt
    29581 ggtgcggcag cggcgggcgg ctatgctgcc gggcgttttt tgcagcccgc gatcgggttc
    29641 ggcaaagaga tgtcccgcgt tcaggcgctg acgcgaatcg acaaaaacag cccgcagttt
    29701 aaggcgctgc gtgagcaggc gttaaaactt ggctctgaaa cacagtttac tgcgagtgat
    29761 gccgccagtg ggcagagctt tctggcaatg gctggtttta ctccgcaggc cattcaggcc
    29821 gcattgcccg gtgttcttaa tatggcgctg gcaggtggcg tcgaactcgg cgagacggct
    29881 gatataggct ccaatatcct cacacagttc aacctgacag ccgatcaaat ggaccgggtt
    29941 ggcgatacgc tgacagcggc attcacccgg accaatactg atttacgcgc gctgggcgaa
    30001 accatgaagt ataccggtcc ggttgccgca aaacttggta tcagtcttga agaagcggca
    30061 gccatggccg ggatgcttgc caataatggt cttcgtggaa gcgatgctgg tacggccatg
    30121 cgcgcaagtc tgtcccgcct tgcatcaccg ccaaaagctg cggctgatgc gctgaaagag
    30181 ctgggggtgt cagttgctga cgccagaggc aaaatgcgcc cgatggagga tgtgctgctt
    30241 gatctctata aggcgacaca aaaatacgga caggtggacc aggtttcctt cttcaaggac
    30301 atcgccggag aagaggcgtt cgttggtttg cagacgcttg ttgcggcggc tggttcagga
    30361 gagctgcaaa aactgaccag agaattgcag ggggcaaggg gagaggccga tcgcgttgca
    30421 aaagtaatgg ccgataatct tgatggggac ctgaaaaatc tcgacagcgc atgggaaggt
    30481 cttcgtattc gcatcagtga tctggttgac ggtccgctgc gttctgtcac gcagtggctc
    30541 acgcgggtgc ttgaaaaaat cacctcgctg gcgcaggccc atccggtact gacgcgccag
    30601 ctactgatag caggcggtgc gttgctggca atgactgcaa cggttggctc gttgtcgctg
    30661 gctattggtg tgcttgctgg cccgctggca aaactgcgtc ttggcttttc cctcctgacc
    30721 ggttcaatga atgctgtcag actcctgcca gcactatggg gaatggtgac gggttccgtt
    30781 tcgttactgg ggggcgctat cggggcgttg ttcagtccgg tcggccttat cgtggctgcg
    30841 cttgccggag ctgccgttct catctggaaa tactgggatc ccatcagggc attttttgcc
    30901 ggggtgttca gcgggattat ggaaaggctg accccgttgc gcgaaacctt tgaacggttt
    30961 ggtcctgttt ttgacgcaat cgggagtggg atcagccagg tgtttaactg gtttaaatcg
    31021 ctgctgtctc cgatggagtc cagcaaggaa actctggata aatgtaccag tgctggcgag
    31081 atattcggta acgttcttgg cggtgcgtta caacttgttc tgacacctgc aaaaatgttg
    31141 ctggatacgc tggcgtggat acttgaaaag cttggtgtgc ttccggatga agcggaaagg
    31201 gcgcgcaaga aaatcgaaga cgcacagcgt gcggccattc ttcaggacaa ggttgccttg
    31261 cttcaggggg acctggcgaa aatcaatccg ccgaagcctg tggaaaatgg caatggcacc
    31321 ggaggtgata accccaaaga caataaaccg ctcacagaca gcaataccgg tacgctgcgc
    31381 agactcagca aaattgctga taacacaggt aagctggttg aggagacgaa aaaacgcatt
    31441 ggccccggcg atattgtctt taaaaacctg ccccgagcac ttgctgttcg tggggagtgg
    31501 caggagcgga agattgcgca ggtcagtaag cctgcccccg caattaatat cacacccgtg
    31561 gtcccggctc cgctgcctcc ggcgctggtc cctgttgttg cggccagctc ccgcccggtg
    31621 gcggaggcta tacgatctcc agtggcatca gttcctgtaa cttcccgtaa ccgggagcct
    31681 gttgcctccg gatttggtgg tgaaattcat gttcatctgc ataacgttgt tacgcagaat
    31741 ccccgcgaac tggcgaaact ggtcggtgaa atggtcaggg cagaaatgga acggcgcgcc
    31801 cgtgccgggc gtggcagttt ttacgataaa gattgaggag tcatggccat gatgatgatc
    31861 tacggcatgt ttgtttttga gctgcgcacg ctgccgcatc agcagttaca gcaaaacaaa
    31921 agctggcggc atgtgaaaaa tgaacgcgtt aaccgttcag caagctggca gtatatcggt
    31981 gcaggtgatg atcgcatcgt tctttctggt gtgctttatc ctgaaattac aggtggcgaa
    32041 gtgtcgctgt cgctgctgac cacgcaggcg tatacaggac gaccctggcc tttgattgat
    32101 ggcgtcgggc agatttacgg catgtatgtc ctgactgaaa cgaatacgac ccgctccgag
    32161 tttgatcgct acggtaaggc gaaaaagata gaattttcac tgactcttga acgctgtgat
    32221 gaggatttgc gggagcgcct gcaatcctca tcgttcagtg atatgctgtc cggcttcaaa
    32281 gataaggtga catcatctct taacagcgcg gccagttcag ttaaagggct gttctgattt
    32341 aacacaaaaa ccgctaatgg tcagattagc ggttttcatt ttcctgagtc tgcccggttg
    32401 tttcttcagt ctgtatatcg cctacagggt gataacgata aatcgtcgat gtgccaatgc
    32461 cgtaaattat tgccagttgt tttctgtcgt gcccgttttt gattagcctt gctatttgct
    32521 catgctgttc ttttgtcagc ttcggtcgac gtccgcctgt gcgccccctt gcgcgcgctg
    32581 ccgccagccc ggccagtgta cgttcaacaa ttaattcacg ttccatttca gccagggcac
    32641 ccatcacgtg gaagaaaaaa cgccccattg gagaagatgt gtctatgctg tcggtcagac
    32701 tgcgaaaatt aatccctcgc tcccgtagtt ccccgacgag agaaatcaga tgtttcatgc
    32761 ttcgcccgag gcgatccagt ttccagacaa ccagcgtgtc acctttttga aggcgcttta
    32821 aagcgcgttt taatcccggt cggtctgtct ttgtcccgct taatttatct tcaaatattt
    32881 gttcacatcc tgcacaaaca agagcgtttc gttgcaggtc tgtattctgg tcatttgttg
    32941 atacccttac atagccaatc agcacactga atctcccgtc caaaagcgca aatcatgcca
    33001 tgcaggccag aaacggccat tatttaa
//
LOCUS       DAPOXO010000058        33015 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPOXO010000058 DAPOXO010000000
VERSION     DAPOXO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33015
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.058"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..190
                     /locus_tag="ROH59_003135"
     CDS             <1..190
                     /locus_tag="ROH59_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HDX4805583.1"
                     /translation="QALIKEQQDAWQQALALLHLSAIFGDLSNHQPFINEIKIAFANI
                     KNKGIKATISQLLSDEQK"
     gene            187..1203
                     /locus_tag="ROH59_003136"
     CDS             187..1203
                     /locus_tag="ROH59_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000853917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDX4805584.1"
                     /translation="MKTLICQQPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAF
                     AGRQPFFSYPRVLGHEICAEAVSRGSQCQTAQSGQRYSVIPCIPCGECAACREKKTNC
                     CERVSLYGVHQDGGFSEYLAVREDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKA
                     EQNVLVIGAGPIGLATAAIARAKGAHVVVADIDCQRRQHVVDHLAINVFDPTQEGFIA
                     ALSEVFGGELACVVLDATGNKASMSHDVNLIRHGGKIVFIGLYIGELVIDDPTFHKKE
                     TTLLSSRNATREDFALVIELMRSNKIHENLMKNQAFNFFSVGEDYQRNVVENKNMVKG
                     VITF"
     gene            1214..2224
                     /locus_tag="ROH59_003137"
     CDS             1214..2224
                     /locus_tag="ROH59_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ldh family oxidoreductase"
                     /protein_id="HDX4805585.1"
                     /translation="MTTVYVSEENLKSLVHHKLHTAGLDADTAQQVTDVLIHADITGV
                     HSHGVMRVEHYCTRLAAGGLNKAPQFSIEQISPSVAILDSDDGMGHSALISATEHAIK
                     LALEEGLGFVSVKNTSHCGALSYFAEMVTNKGLVAIVMTQTDTCVAPHGGAERFLGTN
                     PIAFGFPVENSHPMIVDMATSATAFGKILHAKETGKHIGEGLAIDKDGYGTTDPHKIE
                     NLLPFGQHKGSGIALAIDALTGMLMNANFGNHIVRMYGDYDKMRKLASLVIAIDPKKL
                     GNPVFAKTMAQMVTELHAVKPAPGIEKVLAPNDPQMHYKEKCQQEGIPVPAGIFHYLA
                     EN"
     gene            2297..3280
                     /locus_tag="ROH59_003138"
     CDS             2297..3280
                     /locus_tag="ROH59_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HDX4805586.1"
                     /translation="MKALRPLTASLMLLTSCLLISNTTLAKTTLKLSHNQDKSHAVHK
                     ALSYLADKTKEYSNGELVIRIYPNATLGNERESLELMNSGALQMVKVNAASLESFAPD
                     YSLFSLPFLFRDRDHYYRVLQSDLGKKILKSSESKGFVGITYYDGGARSFYSNKPITK
                     PEDLAGMKIRVQQSPSAIAMMKALGGVATPMAQGELYTALQQGVVDGGENNTVVYSDM
                     RHAEVAKVYSRDEHTMVPDVLIISTDVLNKLGDKERTALLKAADESMMQMKDVIWPAA
                     EKEAYDKMKGMNATVVDVDKSAFKERVKPLYDEFKAKDAQSAKNLELVESM"
     gene            3322..3804
                     /locus_tag="ROH59_003139"
     CDS             3322..3804
                     /locus_tag="ROH59_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDX4805587.1"
                     /translation="MRTLTHILNKILAGCCCIILAIMVFCVTWQVIARFIFNAPSTVL
                     DEFTQILFMWMILLGGVYTAGLKKHLAIDLLAQKLPAASVLTLDSFIQIIITVFAVIF
                     MIYGGNIVVEKAQHVGQISPVLKWPMDKVYWVMPVSGLILVWYSVMNIIDNYRKRNFH
                     "
     gene            3815..5119
                     /locus_tag="ROH59_003140"
     CDS             3815..5119
                     /locus_tag="ROH59_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HDX4805588.1"
                     /translation="MDFEYIYPVLILFGSFAVMLAIGVPITFAIGLSSLLSIITALPP
                     DAAISVISQKMTVGLDGFTLLAIPFFVLAGNIMNTGGIARRLVNLAQALVGRLPGSLA
                     HCNILANTLFGAISGSAVASAAAVGGIMSPLQEKEGYDPAFSAAVNIASAPIGLMIPP
                     SNVLIVYSLASGGTSVAALFLAGYLPGILTAVALMFVAALYARRHHYPVAERINYRQF
                     LQVFRESIPSLMLIFIIIGGIIAGVFTPTEASAIAVIYSLALAMIYREITLKKLNDIL
                     LDSVVTSSIVLLLVGCSMGMSWAMTNADVPELINELITRVSDNKWVILFIINIILLIV
                     GTFMDITPAILIFTPIFLPIAQHLGIDPIHFGIIMVFNLTIGLCTPPVGTILFVGCSI
                     GKVSIDRAIKPLLPMFLALFVVMAIICYFPQLSLMLPGLFST"
     gene            complement(5190..6602)
                     /gene="ftsP"
                     /locus_tag="ROH59_003141"
     CDS             complement(5190..6602)
                     /gene="ftsP"
                     /locus_tag="ROH59_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HDX4805589.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(6677..7414)
                     /gene="plsC"
                     /locus_tag="ROH59_003142"
                     /gene_synonym="parF"
     CDS             complement(6677..7414)
                     /gene="plsC"
                     /locus_tag="ROH59_003142"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HDX4805590.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAENYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(7649..9907)
                     /gene="parC"
                     /locus_tag="ROH59_003143"
     CDS             complement(7649..9907)
                     /gene="parC"
                     /locus_tag="ROH59_003143"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDX4805591.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDIACYVAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAVIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGI
                     LASERKMNNLLKKELQADAQGYGDERRSPLHEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(10045..11652)
                     /locus_tag="ROH59_003144"
     CDS             complement(10045..11652)
                     /locus_tag="ROH59_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX4805592.1"
                     /translation="MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPG
                     TLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQ
                     WSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKAM
                     DDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDKWV
                     VNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIE
                     KSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATT
                     LTPPEVKGFSATTFDELQKPMSERVAMAKVLLKQAGYDASHPLRFELFYNKYDLHEKT
                     AIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKS
                     DSEENVGHWKNAQYDALLNQAAQTADATKRNALYQQAEVIINQQAPLIPIYYQPLIKL
                     LKPYVGGFPLHNPQDYVYSKELYIKAH"
     gene            complement(11761..12243)
                     /locus_tag="ROH59_003145"
     CDS             complement(11761..12243)
                     /locus_tag="ROH59_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDX4805593.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPDAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTIWGIIRHWLPASGEKMRKAPILFHYTNLAEGMTEQRLEMDVYVPLA
                     "
     gene            complement(12296..12688)
                     /gene="ygiW"
                     /locus_tag="ROH59_003146"
     CDS             complement(12296..12688)
                     /gene="ygiW"
                     /locus_tag="ROH59_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HDX4805594.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            12840..13499
                     /gene="qseB"
                     /locus_tag="ROH59_003147"
     CDS             12840..13499
                     /gene="qseB"
                     /locus_tag="ROH59_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HDX4805595.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            13496..14845
                     /gene="qseC"
                     /locus_tag="ROH59_003148"
     CDS             13496..14845
                     /gene="qseC"
                     /locus_tag="ROH59_003148"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HDX4805596.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDG
                     DNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
                     AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRP
                     LVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKAL
                     LQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQANID
                     VRLTLNANGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGV
                     TPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVDFGNAKQGGFEAKVSW"
     gene            complement(14891..15223)
                     /locus_tag="ROH59_003149"
     CDS             complement(14891..15223)
                     /locus_tag="ROH59_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2645 family protein"
                     /protein_id="HDX4805597.1"
                     /translation="MLKKQLLSIFEALLYIMLTYWLIDSFFAFNKYDWMLESGDNICS
                     IPSVSGEDRILQAMIAAFFLLTPLIILILRKLFMREMFEFWLYVFSLVICLGCGWWLF
                     WGRFIFCY"
     gene            complement(15230..16422)
                     /locus_tag="ROH59_003150"
                     /pseudo
     CDS             complement(15230..16422)
                     /locus_tag="ROH59_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001363036.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
     gene            16673..17254
                     /gene="mdaB"
                     /locus_tag="ROH59_003151"
     CDS             16673..17254
                     /gene="mdaB"
                     /locus_tag="ROH59_003151"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HDX4805598.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            17285..17599
                     /locus_tag="ROH59_003152"
     CDS             17285..17599
                     /locus_tag="ROH59_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDX4805599.1"
                     /translation="MITVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAVKGDVLEMNIRILQP
                     GL"
     gene            complement(17644..18531)
                     /locus_tag="ROH59_003153"
     CDS             complement(17644..18531)
                     /locus_tag="ROH59_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDX4805600.1"
                     /translation="MIQKDKVRVDIFGERFRTRASQLTPGLRVVASYINEHREVVLEQ
                     TAMEIAATLNTSDATVIRAIQALGFAGLRDLKRTLEQWLGPALSSSEKMSTTVSNLTS
                     DVNTAIDFVLEGHLYTCNVLSEPENRHALAQAVALLVQARQVAIFGIGASGILADYTA
                     RLFNRIGLPATALNRTGIGLAEQLIALQRGDVLIMMAQKSAHREGLTTLREARRLGIP
                     VILLTNALDSRFSKDASIVIHVPRGDEKGKTPLHGTVLLCLEMIVWSVASAVPQRAVK
                     TIKRINDFHRGLKTGRKNG"
     gene            complement(18528..19475)
                     /locus_tag="ROH59_003154"
     CDS             complement(18528..19475)
                     /locus_tag="ROH59_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HDX4805601.1"
                     /translation="MRLFFSLLILLSFFSRATEPVQVFTDDLGRKVTVPAHPKRIVSL
                     HDLDITIPLIELGVPPVASHGRTRPDGSHFIRSGALLTGVDFDNSSIAFIGTADIDIE
                     AIVAAKPDLIITEPTRNTPIEQLEKIAPTVSIDHLKGGAPEIYRKLAELTGTQSQLAI
                     LERRYQAQINALKATLDSQKITVSVIQANQGKINVMHSYHSLGRVLRDAGFRFPPLIE
                     SIPEGGRMDVSAERLPELDADFVFATWRGDTGGKPQDELAAMEKVMPGWCQFLTACRS
                     GRYVLISREEAISNSFASLGLMAAQIQSQIAGRPLPEAK"
     gene            complement(19486..20523)
                     /locus_tag="ROH59_003155"
     CDS             complement(19486..20523)
                     /locus_tag="ROH59_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311941.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDX4805602.1"
                     /translation="MNVGLRPLRVGKFSTLVRPKNLLLLGGLFLLAVGILIFGLMQGS
                     FSVPASEVGRALFAPENVSTDARYIVQDIRLPRVIMALLCGAMLGMAGAAMQSIARNG
                     LADPGLIGVKEGCSVAVLWLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCARDISRPR
                     FVLIGIGVSWFFAAGIGVFMTTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAA
                     LLLLFTARTADIALLGHQVATGLGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLI
                     APHISRFILRGGQTTLLLGSAVSGALLVILADSIGRLAFLPLQLPAGIIISLIGGPFF
                     LLLLWQRRNSF"
     gene            complement(20532..21515)
                     /locus_tag="ROH59_003156"
     CDS             complement(20532..21515)
                     /locus_tag="ROH59_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDX4805603.1"
                     /translation="MMRTGLVTVIFLALLLVGCVVYPGIGARFIAPQTVLQAFLHFDP
                     QNFDHNVIVRLRLPRLAAALLTGASLGVAGALLQAVIRNPLGEPHILGLNAGAALAVV
                     AASALGLAFPVGRPLLASTGGALLFLLILLLSSAGRSGLTPMKVTLCGVALSAFVSSI
                     TAAILILDEQTLLAMRTWLAGDLAGQDWATLGTSAWFSLGGFVLALYLAPSLNMLALG
                     DRMAQGLGVSVLRTRTFTLLAIALLCGAAVSIAGPIGFVGLLVPQIVRRLVSADLRVL
                     LPLSACVGALLLLLADIIARTLFTPHELATGVMTALVGAPVFVIMATRMFK"
     gene            complement(21512..22321)
                     /locus_tag="ROH59_003157"
     CDS             complement(21512..22321)
                     /locus_tag="ROH59_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4805604.1"
                     /translation="MAHNAKGQGLILDNVSAGYHKKIIVDGVSFSVPTEKMTVLVGAN
                     GCGKSTLLSTIARILQPMGGSILLDGKAIHEQPTKALSRRLGILPQSPLLPEGLTVYE
                     LVSRGRFPWQNFIRQWSDADEQAVEEALKLTGTQEFAHLPVEKLSGGQRQRCWIAMVL
                     AQKTPYILLDEPTTWLDLRYQVEILELLHDLTRHHGRTVVVVLHDLNFAVNYGDTLIF
                     LRQGKVVRVLNEGEHCTPELVKAVFDVDVHASINPLTGKPFFMPFRGVEKV"
     gene            22695..24836
                     /locus_tag="ROH59_003158"
     CDS             22695..24836
                     /locus_tag="ROH59_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HDX4805605.1"
                     /translation="MAMFTPSFSGLKGRALFSLLFAAPMIHATDSVTTKDGETITVTA
                     DANTATEATDGYQPLSTSTATLTDMPMLDIPQVVNTVSDQVLENQNATTLDEALYNVS
                     NVVQTNTLGGTQDAFVRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTL
                     YGILDPGGLINVVTKRPEKTFHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEV
                     QDEDYWRNFGKERSTFIAPSLTWFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVN
                     VDRKIRFDEPFNITDGQSDLAQLNAEYHLNSQWTARFDYSYSQDKYSDNQARVTAYDA
                     TTGTLTRRVDATQGSTQRMHATRADLQGNVDIAGFYNEILGGVSYEYYDLLRTDMIRC
                     KKAKDFNIYNPVYGNTSKCTTVSASDSDQTIKQESYSAYAQDALYLTDNWIAVAGIRY
                     QYYTQYAGKGRPFNVNTDSRDEQWTPKLGLVYKLTPSVSLFANYSQTFMPQSSIASYI
                     GDLPPESSNAYEVGAKFELFDGITADIALFDIHKRNVLYTESIGDETIAKTAGRVRSR
                     GVEVDLAGALTENINIIASYGYTDAKVLEDPDYAGKPLPNVPRHTGSLFLTYDIHNMP
                     GNNTLTFGGGGHGVSRRSATNGADYYLPGYFVADAFAAYKMKLQYPVTLQLNVKNLFD
                     KTYYTSSIATNNLGNQIGDPREVQFTVKMEF"
     gene            complement(24900..26792)
                     /gene="parE"
                     /locus_tag="ROH59_003159"
     CDS             complement(24900..26792)
                     /gene="parE"
                     /locus_tag="ROH59_003159"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDX4805606.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQIYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRLDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(26821..27402)
                     /gene="yqiA"
                     /locus_tag="ROH59_003160"
     CDS             complement(26821..27402)
                     /gene="yqiA"
                     /locus_tag="ROH59_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HDX4805607.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            complement(27402..28229)
                     /gene="cpdA"
                     /locus_tag="ROH59_003161"
     CDS             complement(27402..28229)
                     /gene="cpdA"
                     /locus_tag="ROH59_003161"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HDX4805608.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADARFQPDTASEGY"
     gene            complement(28254..28676)
                     /locus_tag="ROH59_003162"
     CDS             complement(28254..28676)
                     /locus_tag="ROH59_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HDX4805609.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            complement(28677..29306)
                     /gene="nudF"
                     /locus_tag="ROH59_003163"
     CDS             complement(28677..29306)
                     /gene="nudF"
                     /locus_tag="ROH59_003163"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HDX4805610.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            29511..30992
                     /gene="tolC"
                     /locus_tag="ROH59_003164"
     CDS             29511..30992
                     /gene="tolC"
                     /locus_tag="ROH59_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HDX4805611.1"
                     /translation="MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNTLLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            31140..31811
                     /locus_tag="ROH59_003165"
     CDS             31140..31811
                     /locus_tag="ROH59_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HDX4805612.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            31817..32977
                     /locus_tag="ROH59_003166"
     CDS             31817..32977
                     /locus_tag="ROH59_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDX4805613.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLSQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
BASE COUNT         8607 a         8446 c         7898 g         8064 t
ORIGIN      
        1 tcaggcgcta ataaaggaac aacaagacgc atggcaacag gcgctcgcat tactgcacct
       61 tagcgccata tttggtgatt taagcaacca tcagccattt ataaatgaaa taaaaatcgc
      121 ctttgcaaat ataaaaaaca aaggcatcaa ggccaccatc agccaattat tatcggatga
      181 gcagaaatga aaacattaat ttgtcagcag cctggcgtta tggaatatgt ggaaaaggat
      241 attcccacac cagcagataa tgaagtgctg ttaaaaatca aagctgtggg tatttgtggt
      301 actgatattc acgcttttgc cggcagacag ccttttttta gctacccacg tgtattaggt
      361 catgaaatat gcgccgaagc ggtttcgcga ggcagccagt gccaaacagc acaatcaggc
      421 cagcgctatt ccgtcatccc atgcattcca tgtggcgagt gcgcagcctg tcgggaaaag
      481 aaaacgaact gctgcgaacg tgtttcgctg tatggcgtgc atcaggatgg gggctttagt
      541 gagtaccttg cggtacgtga agacaacctt gtgcctctcc ctgacgaggt cagcgacagt
      601 gccggagcat tggttgaatg tttcgccatt ggtgcacatg ccgttcgtcg ggcagagatc
      661 aaggctgaac aaaacgtact ggtgattggc gctgggccaa tcggtctggc taccgcagcc
      721 atcgccaggg ctaaaggggc gcatgttgtt gttgctgata ttgactgtca acgtcgccag
      781 cacgttgtgg atcatctggc aattaatgtc ttcgacccaa cacaggaagg ttttattgcc
      841 gcgcttagtg aagtatttgg cggcgaactg gcttgcgtag tcctggatgc gacgggaaat
      901 aaagcttcaa tgagtcatga tgtaaatctt attcgtcatg gcggcaaaat tgttttcatc
      961 ggtttgtaca ttggtgaact tgttattgac gatccgacct tccataaaaa agagacaacg
     1021 ttactcagca gccgcaatgc cacacgggaa gattttgcgt tggtgattga actgatgcgc
     1081 agcaataaaa ttcacgaaaa tttaatgaaa aaccaggcgt tcaatttctt tagtgttggc
     1141 gaagattacc agcgtaacgt tgtagaaaat aaaaatatgg tcaagggtgt gatcactttt
     1201 taagggaaca tatatgacaa ctgtttatgt cagtgaagaa aatttaaaat cactggtgca
     1261 ccacaaatta cataccgccg ggctggatgc cgacactgca caacaggtga cagatgtttt
     1321 aatacatgcc gatattacag gtgtgcattc acatggagtt atgcgtgtcg aacattattg
     1381 tacccgcctt gctgccggag ggttaaataa agccccgcag tttagtattg agcaaatttc
     1441 accgtcagtg gccattctcg actctgacga cggaatgggg cattcggcat taattagcgc
     1501 cactgagcac gctattaaac tggccctgga agagggtctc ggttttgtta gcgttaaaaa
     1561 tacgtctcac tgtggcgcgt tatcttattt tgcagagatg gtcaccaaca aagggttggt
     1621 tgctatcgta atgacgcaaa ccgatacctg cgtggctccc catggcggcg ccgagcgctt
     1681 tttgggtact aaccccatcg cctttggttt cccggtggaa aacagccatc cgatgattgt
     1741 tgatatggca accagtgcca cggcttttgg caaaatactt catgcaaagg aaacaggaaa
     1801 acatattggt gaagggctgg cgatagataa agacggttat ggcaccactg atccgcataa
     1861 gattgaaaac ctgctacctt tcggccaaca caaaggttca ggcattgcgc tggctattga
     1921 tgcactgact ggcatgctga tgaatgcgaa ttttggcaac catattgttc gcatgtatgg
     1981 tgattatgac aagatgcgta agctggcaag tttggttatt gccatcgatc cgaaaaagct
     2041 cggcaatcct gtttttgcaa aaaccatggc gcaaatggtc acggagttgc atgccgttaa
     2101 accggctccc ggtatcgaaa aagtgttagc gccgaacgat ccgcaaatgc actacaaaga
     2161 aaaatgccaa caggaaggta ttccggttcc agcaggaata ttccattatc tggcagagaa
     2221 ttaatcacta ctttttatta taacgataga aaagcgctgt atttatcgtt tctgttatat
     2281 taaccaggag caggatatga aagcacttcg tcctctgacg gcatcgctta tgctgttaac
     2341 cagttgttta ttaatatcta ataccacact ggcaaaaaca acattaaaac tgagtcataa
     2401 tcaggataaa agccatgctg tccataaagc attaagctat ttagcggata aaaccaaaga
     2461 gtattctaat ggtgaattag ttattcgcat ttacccaaat gcgacattag gcaatgagcg
     2521 tgaatcactg gaattaatga actccggtgc attacagatg gttaaggtta atgctgcatc
     2581 actagaatca tttgccccgg attacagcct tttcagtctg ccgttcttat tccgcgaccg
     2641 tgatcactat tatcgtgttc tgcaaagtga tttaggtaaa aaaatactta agtcatcaga
     2701 aagcaaaggt tttgttggta ttacgtacta tgacggcggt gcgagaagtt tttattccaa
     2761 taaaccgatt acaaaacccg aagatttagc gggaatgaaa atcagggttc aacaaagccc
     2821 cagcgccatt gcaatgatga aagcactcgg tggtgtcgct accccgatgg cgcaaggcga
     2881 actctacacc gcacttcagc aaggagtggt tgatggcgga gagaacaata ccgttgtcta
     2941 ttccgatatg cgtcacgccg aagtcgcaaa agtctattca cgtgatgaac acaccatggt
     3001 acctgatgtg ttaattatca gcaccgacgt gttgaataaa cttggtgata aagagcgcac
     3061 ggcattatta aaagcagccg atgagtcaat gatgcagatg aaggacgtca tctggcctgc
     3121 ggctgaaaaa gaagcctacg acaaaatgaa agggatgaac gcaacagttg ttgatgttga
     3181 taaatccgct ttcaaagaac gcgtcaaacc gttatacgat gaattcaagg cgaaagatgc
     3241 acaatcagcc aaaaaccttg agctagtaga aagtatgtaa ccctaatggg caggtaattc
     3301 ctgccttttc atggaagact tatgcgaaca ctcactcata ttcttaataa gatccttgcc
     3361 ggatgttgct gcattattct cgccattatg gtgttctgcg taacctggca agttattgca
     3421 cgttttattt ttaacgctcc cagcactgtg cttgatgagt tcacccagat tttatttatg
     3481 tggatgattt tacttggcgg tgtatatact gcggggttaa aaaaacatct ggccattgat
     3541 ttgttggctc aaaaacttcc ggctgcatct gttctgacgc ttgacagttt tatccaaatt
     3601 attattacgg tctttgcggt tattttcatg atctatggcg ggaatattgt tgttgaaaaa
     3661 gcacaacatg ttggacaaat ctctccagta ttaaaatggc caatggataa agtatattgg
     3721 gttatgcctg tcagtgggct tattctggtc tggtattcag taatgaatat tattgacaac
     3781 tatcgtaaac ggaattttca ttaacgaggg aaatatggac tttgaatata tctaccccgt
     3841 cttaatttta tttggcagtt ttgccgtcat gctggcaata ggtgtgccaa ttacttttgc
     3901 gattggtctt tcttcgctgt tatctattat tactgcctta ccacccgatg ccgccatttc
     3961 tgtgatttcg caaaagatga ctgtggggct ggatggcttt acgctattag ccattccctt
     4021 cttcgtgtta gccggaaaca ttatgaatac cggtggtata gccagacgac tggttaacct
     4081 ggcgcaagca ttagttgggc gtcttcctgg ctcactggct cattgtaata tcctcgcgaa
     4141 tacactgttt ggtgcgattt caggttcagc cgttgcgtca gccgccgcgg taggtgggat
     4201 tatgtcacca ctgcaagaaa aagagggata tgatccggcg ttttcagcag cggttaatat
     4261 tgcctctgcc cccattggcc tgatgatccc accgagcaat gtgttgattg tttattccct
     4321 tgccagtggc gggacttctg tcgctgcgtt gttcttagct ggatatctgc cgggcatcct
     4381 caccgctgtt gccttaatgt ttgtagctgc actttatgcc cgacgtcacc attatccggt
     4441 ggccgagcgc attaattacc gtcagttttt acaggtattc cgcgaatcaa ttcctagcct
     4501 gatgcttatt tttatcatta ttggcggtat tatcgcgggg gtatttacgc ctacagaagc
     4561 atcggcaatt gcggtaattt atagtttagc cctggcgatg atttaccggg aaatcactct
     4621 taagaagctc aatgatattc tgttagattc ggtagtaacc agttcaattg ttctgttact
     4681 ggtaggctgc tcgatgggga tgtcatgggc catgacgaat gctgatgttc ctgagttgat
     4741 caacgaactg attacccgcg tttcggataa caaatgggtc attctgttta ttatcaatat
     4801 cattctgttg atcgttggta cctttatgga tatcacgccg gcgatcctga tatttacacc
     4861 tattttcctg ccgatcgccc agcatctggg gattgatccg attcacttcg gcatcattat
     4921 ggttttcaac ttaaccattg gcctttgcac accacctgtc ggcaccattc tgtttgtggg
     4981 atgcagcatt ggtaaggtca gtatcgacag ggcaataaaa ccattactgc cgatgtttct
     5041 ggcattgttt gtagtaatgg caattatttg ttatttcccg cagcttagtc tgatgctgcc
     5101 aggattattt tcgacctgat acacaatgaa gactgcatac tgagtaattt tcaatgcccc
     5161 accactctgt ggggcattga attggtccat tacggtaccg gattgaccaa cagttgccca
     5221 atcgagccac ggtccgccat ttccagcgtc tgactgttga agtagaacgg gaagtgcgcc
     5281 caggaaggct gaccgaaata aacaagcagc tccacttgtc cgtcaaccca aacggtatct
     5341 ttccagcctc tgtcttccgg gaacggcatc gcgccattca cgttacggat ctggaacatc
     5401 acgccttcaa tatggaacgc ttgcggctcg tccgcgcgca ccgtccagcg ttcccacgtt
     5461 ccttgctgcg cagtaacatc aatacggttg acgtcccaca actgcccatt aatccccggg
     5521 tcatcaccca gactgatatc acgacttcga atcggcgaac cggccatgat ttcagttggc
     5581 agcaagcgca tcggaagact gtctgtgacc agcggcagaa ggccggttgg gcgcagcgtt
     5641 agcaccagcg tagaaaccag aatgctggat ggctcaaaga agccacgaat acgatcaaca
     5701 atgctcgccg cttcgccaca ggtaatcgac acttcatcac cgttgctcat atccaccaga
     5761 atctcacgac gctcgcccgg tgccagcgaa agttgcttca ccgatacagg agcgggcagg
     5821 aatccctgat cgccagaaat cacatgtaac gggcgaccat cgctcatctg tagttgatag
     5881 cgacgagagt tcgacgcgtt caacagacgc aagcgcaccc agccacgcga gacttcaacg
     5941 tacgggcttt gtacaccgtt aaccagtagc gtatcgccaa caaagccgcc gcttccaggt
     6001 tcgttatatt ctggcgtacc aaagttatcc agccgtttat cctgaataat gacaggaaaa
     6061 tcatccacac cataatggtt ggggataggc agcgatttac tgacttcatc ttccaccagc
     6121 cacattccgg caaggccgtt atagacctgc tgagccgtgc ggttgggagt attggcgtga
     6181 taccacagag tagctgcgtt ctggcgaatg ggcagtacgg gtgcccagtc agcgtttggc
     6241 gacatcatcc gtgccggacc gcccatcagc gggccaggta cctgtagccc ggccaccgtc
     6301 attgagacat tttctgtcag gcggttgctg taaataagct taacatcgtc gcccttccag
     6361 acgcggatag tcggccccag gtaacgacca ttgattcccc aaaccgacgc gcgtgtccct
     6421 ggcgtaaatg accagtgcgc acgttgtaca gtcataaaca gcggttgccc acggcgagat
     6481 tcaagcagcg gcggaacggg tagcggttgc tgttgcccgg ctgcgctggc cttcagggga
     6541 acagcgcctg cacaaagtgc aatccccgat gcctgaatga actgacgccg actgagtgac
     6601 atatttgctc catgtaaaac tggctaaagt aataccgtgc aggaaagtgt tccccgcaaa
     6661 aatacagatt gccgacttaa acttttccgg cggcttcgcg ttctgcgact tctttatcga
     6721 gctcggcgat tttttgttcc attatcgaac gacaatgggc agccaactcg cgaacctgat
     6781 ctttgccata ctgactgacg tcaattggcg gcagcatttc gacaatcacc agaccgttgt
     6841 gtagccgatt aagattaatc ttattcgaag ttgtagagac gcacacgggt ataatcggga
     6901 cgcccgccgc aattgccgcg tgaaatgccc cggtcttgaa cggcagcagg ccgcgaccac
     6961 ggctgcgggt tccttccggg aacatccaga tggaaatacg gcgttttttg aagtgattca
     7021 ctacttccgc aatagtgccg tgagctttag tgcgattgtt tctgtcgatc aataagttgc
     7081 cggttaacca atacaactgc ccgaagaagg ggatccacag caaactcttt ttacctaccg
     7141 tcactgtcgg cggctgcaca atgttcgatg ccgtcaccat gtcataattg ttctggtggt
     7201 tagcaatata gatagcattg ccgtagtttt cagcgtctgc aggtttgcgg cactccactt
     7261 tcaggccgaa aagcggcgca agacgaccaa acatatgccc aaaggtggcc acatgtttcg
     7321 gattacgcgg gctgaaaagg cagtaaatgg agccgaatac acagactaag atgctgtaaa
     7381 tcacggtaat aataagacga aagatatata gcataacacc ctctgaaggt ctgagagact
     7441 ggcattgtac gtcacctgaa aatcaggtta gggcattgtt aaaagccgct ctctggaaaa
     7501 gcgtattgtt aatcgcaacg catgaataaa caacggtttc aagggaattt ttatcgtttc
     7561 cggggattga atacgctgcc ggatgacgac ttaacgtttc atccggcgtt ccttgcaagc
     7621 gggaggaaac agcgccctcc ccggcatatt actcttcgct atcaccgctg ctggcacggc
     7681 gaggagagtc gatctcaaca cgatcgatac gctgcaaacc gcgcatcaac gtaccgcggc
     7741 gtccacgttc gccagtgact ttctgtagct cttccggacg cagtttaatt ttgcgtttcc
     7801 caacatgaat ggtcagcgtg ctttgcggcg gcagaacgta cagttgcgcc aggccatcct
     7861 cgccacgcgc ggcttctgcc gatggaatgt tgataatctt gttgcctttg cccttcgaca
     7921 gctgcggcag atcgcttacc gggaacatca acatacggcc tgcctgagtg attgccagca
     7981 gcatatcgga agcatcttca atcaccaccg gcggcataac atgggcattt tccggtaagg
     8041 tgatcaaagc cttacctgca cggttacgcg ccaccagatc gttaaaggtg cagacgaaac
     8101 cgtaacccgc atcggaagcc atcagcagtt tctgatcgtc gctttccatc agcatatggt
     8161 caacggtcgc tccaggcggc aacgttaatt tgccggtgag cggctcgccc tgaccacgcg
     8221 ccgacggcag cgtaatcggg tcgatggcat agctacgacc ggtggaatca acaaacacta
     8281 ccggttggtt gctcttacct ttcaccgccg ctttgaagct atcacccgct ttataattca
     8341 ggcccggcgc gtcgatatca tggcctttag cgctgcgtac ccagcccatc tgcgacagca
     8401 caatggtgac aggttcagac ggcagcatgt cgtgctcgct catcgctttc gcttcttcgc
     8461 gttcatgcaa cggcgaacga cgttcgtcac cgtagccttg cgcgtctgcc tgcagttctt
     8521 tcttcagcag gttattcatt ttacgctcgg aagccaaaat gccctgcaac tggtcgcgct
     8581 ctttttccag ctcactctgc tcaccgcgaa tcttcatctc ttccagtttg gcaagatgac
     8641 gcagtttcag ttcgaggatc gcttccgcct gggtttccgt aaggccaaac cgcgacatca
     8701 gcgccggttt cggttcatct tcattacgaa tgatctcaat cacttcgtcg atattgagaa
     8761 acgccaccag caaaccttcg aggatatgca ggcgcttgag aactttctcc agacgatagt
     8821 tcagtcggcg gcgcacggta tcgcggcgga acaccagcca ttcggagagg atttccagca
     8881 ggtttttcac cgccggacga ccatccagac cgatcatatt gaggttaatg cgatagctct
     8941 tttccagatc ggtggtagca aagaggtggt tcatcacctg atccatatcc acgcggttgg
     9001 aacgcggcac aatcaccaga cgggtcgggt tctcgtggtc agattcatcg cgcagatcgt
     9061 caaccatcgg cagctttttg ttgcgcattt gcgcagcaat ttgctccagt acgcgcgcac
     9121 ctgaaacctg atgcggcaat gcgctgataa ccaccgcgcc atcttccttc ttccaaaccg
     9181 cgcgcatacg cactgaacca cgtccgttct cgtagatttt acgaatctcg gcgcgcgaag
     9241 tgataatttc cgcttcagtc ggataatccg gcccctgcac gatatccagc agctgatcga
     9301 gcgtggtttt cggctggtcg attaaggcaa ttaccgcctg agccacttca cgcaggttat
     9361 gcggtggaat atcggtcgcc atgccgacgg caataccggt ggtgccgtta agcaaaatgt
     9421 ttggcagacg ggcaggcagc attttcggct cctgcaaagt gccgtcgaag tttggcaccc
     9481 agtcagccgt cccctgcccc agctcgctca atagcagctc ggaatatttc gacaaccggg
     9541 attcggtgta acgcattgcc gcgaacgatt tcggatcgtc cggcgccccc cagttcccct
     9601 gaccatcaac cagcggataa cggtaagaga acggctgcgc catcaggacc atcgctacat
     9661 aacaggcaat atcgccgtgc ggatggtatt tacccagtac gtcaccgacg gtacgggccg
     9721 attttttaaa tttggcgctg gcattcaggc ccagctcaga catcgcatac acaatgcggc
     9781 gctgaacagg tttcagacca tcaccaataa acggcaacgc acggtccatg atcacgtaca
     9841 tggagtagtt taagtaggcg ttttccgtaa attcatgtag cgcaaggcgc tctgccatat
     9901 cgctcattaa ttctgattcc tcaacttatt cgccagcctt caaaggggca atattgccgg
     9961 agatactaca ttatctgccg cgtcgagtca caggagatca gcgtgaatag cgccgccgga
    10021 cgtgctccgg cggcgataaa ggcatcaatg tgccttgata tacaactctt tgctgtagac
    10081 ataatcctgg ggattatgca gcggaaaacc gccaacgtag ggtttaagca gtttgattaa
    10141 cggctgatag tagatgggaa tcagcggtgc ctgctggttg atgatcactt ctgcctgctg
    10201 atacagcgca ttacgctttg ttgcatcagc cgtttgtgcc gcctggttta gtaaggcgtc
    10261 atactgcgcg tttttccagt ggccgacgtt ttcttcacta tcgcttttga gcgtgttcag
    10321 gaagctggag gcatcattgt acgtcgcatc ccacgactgc cgagacagca taaaatcacc
    10381 ggctcgtcgg gcatcaagat aggttttcca ctccattgtg cgcagcgtca cctgtgcacc
    10441 cagccatttt ttccattcgg aagacaacgc tatcgcggtc ttttcatgca gatcgtactt
    10501 gttgtagaac agctcaaagc gtagcggatg agaggcgtcg tatcccgcct gtttcagcaa
    10561 gacttttgcc atcgcgacgc gctcactcat tggcttttgc agttcatcga acgtcgtcgc
    10621 gctaaagcct tttacctctg gcggcgtcag cgtggttgcg ggcgttctca accccagtac
    10681 cttttgcgca ataagctgtc gatcaaccgt aagatatagc gcccgacgca cccgcacatc
    10741 gttaaatggc ggtttctcaa ggttaaagtt gtaatattcg ctgttcagac gcgggataat
    10801 tcgtagctcg ccaggcagtg atttttcaat ggcgggaatt tgctgcgccg gaacccaggt
    10861 gagatcgacc tctcccgcgc gatagcggtt atagccggtg accgaattat ccagcgccag
    10921 atactcaacc tgttgcaata ctgtatgttg cgcatcgcgg tactttggat ttttgcgtgc
    10981 agtaatcttt tcgttaacta cccatttatc aagcacaaag gcaccgttgt aaaccatgtt
    11041 ctctggctta ctccagctat cgccatgttt agcgatgaca tgatgaggaa ccgggaacag
    11101 cgtcggccag gcgagcatcg tcgtgaacca aggaaccggc tgctcaagcg taacttcaag
    11161 agtacgatca tccatcgctt tgacacccag cgatgtaaca tctgctttac ccgcaacaat
    11221 agccgcggca ttgttaatgt gcgcctgtgc cagatagcca gcaaaagggc ttgccgtttt
    11281 cgggtcaacc gcgcgctgcc agccgaggac aaaatcctct gccgtcagag gctgaccgtc
    11341 tgaccactgc aaaccgctac gcagatggaa aatatagcgc ttgccgccgt caagtatctc
    11401 ccagcgttca gcctgagcgg gctgcacctg gccttcaccg tccatccata ccagaccttc
    11461 aaacagatcc agcacaatct gcgcggcggt attctcctct accttttgcg ggtcgagcgt
    11521 gcctgggtcg ctatgattgt tgtaacgaaa gacttgttgc ggggcgagcg gtgtgttggc
    11581 gggaacgtca gcagcgtaga gaggagccgc acttaccagg ctgaccagcc ataataaatt
    11641 tcgcgtatac atggtattcc ttaccggaga aattataagc ccgacaacaa tacgcctgtg
    11701 gcattgtttg ctcaaactta tcgcgagtga tttggctcac actccggtaa agattcccca
    11761 tcacgctaac ggtacataaa catccatttc cagtcgctgc tctgtcatcc cttcggcaag
    11821 attggtgtag tgaaacagaa tcggtgcttt acgcattttc tcgccgcttg caggcagcca
    11881 gtggcgaatg atgccccata tcgtgtgtga aatatcgtcc agctcgccaa catggcgggc
    11941 cacagcataa cgtccaccgg taagttcacc attacttacg ccataacgat tatcggggat
    12001 cggttcgcta acgctgccgc agatatcaaa gcgaaacgca tctggtgcgg tggtggcagg
    12061 gtcgtcccag gcgacgccaa aagtctggct ttggttaaca ggagaaagcc ccgtctcttt
    12121 acgccacatg ataaatttcg ccacgctgta gttgagcaac tcagggctac agcggtgcgg
    12181 caacatcgcc acagggattg atgggaaatc gataatattt acatccagtg tcaggtttgt
    12241 cattttgcct ccctgcgaaa ttattcccgg gaacgcgtcc cgggagcggt aacaattacg
    12301 gatttacttt gcggatctgt ttgacgtcaa tttcaacaga gttccagtct ttatcgactt
    12361 caccctgaat ctcaaccgta tctttcggcg tcaccgtcac gccgttccag cgtttatggt
    12421 cgatatcaac attgatagta ccgctggcat ctttgaacac gtagagatcg tcagagatgc
    12481 gttcaacgat attgccgcgt agggttaccc aggtgtcgtc acgcagggat tttgcgcttt
    12541 ctacagtcgt tacgctgccg ttcggcccct ggaatcctcc ggcctgactt tgcgttgccg
    12601 atgggccaga aaaacctccc tgctctgctg ccataaccgg tgcactgcac agggccatta
    12661 ctgcgattac tgctgcgaat tttttcatgt ttattactcc ctttaatgtc tgtttccgag
    12721 catttaacaa gatagtcctt aacaacttct taagggaaaa aaataaaatt taatgctgta
    12781 cagagcgcgt tacaacacgg tttactggca gcaaatacgg ttatcgcagg gatgaaaaaa
    12841 tgcgaatttt actgatagaa gatgacatgc tgattggcga cggcatcaaa acgggcctta
    12901 gtaaaatggg ttttagcgtc gactggttta cacaaggtcg tcagggaaaa gaggcgctat
    12961 atagcgcacc ttatgatgcg gtgatcctgg atttaacctt accaggcatg gatggtcgcg
    13021 atattttgcg cgaatggcga gaaaaaggtc agcgtgagcc tgtattgatc ctgactgcgc
    13081 gcgatgcgct ggcggaacgt gtagaagggc tgcgtctggg agctgacgat tatctgtgta
    13141 aaccttttgc gttgatagaa gtcgccgcca ggctggaagc tctgatgcgc cgaaccaacg
    13201 gccaggccag caacgagctg cgccacggca acgtcatgct cgaccccggc aaacgtatcg
    13261 ccacgctggc tggcgaaccc ttaacgctga aaccaaaaga atttgccctg ctggaattac
    13321 tgatgcgtaa cgctggtcgg gtactgccgc gcaaactgat tgaagagaaa ctgtatacct
    13381 gggacgaaga ggtcaccagt aatgccgttg aagtgcatgt gcatcatctg cgacgcaaac
    13441 tcggtagtga ttttattcgt accgtgcatg gtattggcta cacattaggt gagaaatgaa
    13501 atttacccaa cgtcttagtc tgcgagtcag gctgacgcta atctttttaa ttctggcctc
    13561 ggtgacctgg ctgctttcca gctttgtcgc ctggaaacaa acaacggata acgtcgatga
    13621 gttgttcgac acccaactga tgctgtttgc caaacggtta agtacgctcg atctcaacga
    13681 aatcaacgcg gcggatcgca tggcacagac gccaaataaa ttaaaacacg gtcatgttga
    13741 tgacgatgcg ctgacttttg ccatctttac ccacgacggc agaatggtcc ttaacgatgg
    13801 cgataacgga gaagatattc cctatagcta tcagcgggaa ggttttgctg acgggcaact
    13861 ggtcggtgaa gacgatccct ggcgttttgt ctggatgacc tcacctgatg gcaaatatcg
    13921 catcgttgtg ggtcaggaat gggaataccg tgaagacatg gcgctggcga ttgttgccgg
    13981 acaattgatc ccgtggctgg tcgcactgcc gattatgtta atcatcatga tggtgctact
    14041 gggtcgtgaa ctcgcgccgc tgaacaaact ggcgctggca ctacgtatgc gtgacccaga
    14101 ctcggaaaaa ccactaaacg cgacgggcgt acccagcgaa gtgcgcccac tggttgagtc
    14161 gctaaatcaa ctgttcgccc gcacacatgc gatgatggtt cgtgaacgac gctttacctc
    14221 cgacgcagct cacgaacttc gtagcccgtt aacggcgctg aaagtgcaaa ccgaagttgc
    14281 tcagctctct gacgatgatc cgcaggcgcg gaaaaaagcg ctgctccaat tacattccgg
    14341 gatcgatcgc gctactcgtc tggttgatca actgctcacg ctatcgcggc tggactcact
    14401 ggataacctt caggacgtcg cggagatccc gcttgaagat ctcctgcaat cgtcggtgat
    14461 ggatatttac cacacggcgc agcaggcgaa cattgacgtg cgactgacac tcaatgccaa
    14521 cggcatcaaa cgcaccggac aaccgctatt gctaagtttg ttggtgcgaa atttgctgga
    14581 taacgccgtg cgttacagtc cacaaggtag cgtggtagac gtcacgctga atgccgataa
    14641 tttcatcgtg agggataacg gccctggtgt gacaccagag gcactggcgc gaattggcga
    14701 acgcttctat cgcccacccg gacaaaccgc taccggcagt ggacttgggc tatcgattgt
    14761 ccagcgaatc gccaaattgc atggcatgaa tgttgatttt gggaatgcga aacaaggtgg
    14821 atttgaagcg aaggtaagct ggtaacttct ctgtctatga gagccgttaa aacgactctc
    14881 atagacttta ctaatagcaa aatataaacc gtccccaaaa aagccaccaa ccacaaccca
    14941 gacaaataac gagcgagaat acatatagcc aaaactcgaa catttcccgc ataaagagtt
    15001 ttcttaagat aagaataata agtggtgtca gaagaaaaaa tgctgcaatc attgcttgta
    15061 atatacgatc ttcgcctgaa acagaaggta tactgcaaat attgtctccc gactcaagca
    15121 tccagtcata cttattgaaa gcaaaaaaag aatctattaa ccaataagta agcattatat
    15181 ataatagtgc ttcaaatatt gatagtagtt gtttttttaa catatctgat tactcattaa
    15241 tcaatttttt gatatgttct ctaatctcta acaacctcat accataagag atgaatttat
    15301 aatcatctgt atcacgcgca ggcaaattat taattaaaca aataaaaaaa cccaaatctc
    15361 gttcaacacc acgattatat ctaataccag ccataatata ctgctcattc gtcatataca
    15421 gtgttgccga agagggataa tcaaaaagaa caagatctct taaataagta gcagcaattt
    15481 gaaaggtaaa atcatcctcc attaggcatg tcgctaactc taactgattt ctggtagtta
    15541 attctgaagg gtctagacct agagtaatcg ctgcggttcg tatttgtata cccattgagc
    15601 caaatgatgt tttattttca ggcatatcta acaatccgat cattcttttt gtttcatata
    15661 tctgaaactt ataattttca ggcatacctc ctgactcaat ccaggccacg ccgcccagta
    15721 actctggacg aattccagcg gcgtatgcat atttaattat tttgtctcta ttatattgta
    15781 catatgcatc tttataagca tttaaataat atactcctga acggcgacgc gaatcatttt
    15841 ttcctaactt ccagagtaaa acgtccattt catcccattt acggaacttc gcttgtggaa
    15901 ttgtacaata tctatttttt atagtgagat cgcttttcat atttaaaaaa tcctttcttc
    15961 ccaacaacta tatgattccg tactcgcgat atggtgcttc catgttatat ttttataatt
    16021 aagaacaatg acctcttccg gctgattacc cgcatgtgta attgagtgtg gataacatgt
    16081 cagaatattc gataaatgtg ctccttgcaa ttcaattgtg taaaaccttt caatacaacc
    16141 gccagaatta attctataaa aattaaatac agctgataac tcttcatttt cagaaagagc
    16201 ggcatttaat aaaggggagg atttatctat tggcttgtaa aattttatgg ggtgatgcac
    16261 tacattatac tctcgactta aagaatggtc gaactgtaaa acaaaaattt catccacatg
    16321 atttatttga tatttattac caatagatgc atacgaacca caaccctcag agatcaaacc
    16381 ttgtattttc cctttaattg ataagtatat catatttgac atatatattc tccataatca
    16441 ttttttccga aaaactcctg tatcatttgc ataatacatc tctcctgtgg gagcttatgg
    16501 gaagttgatt taagtattgt cattttcaga aaatatttat cccgcatcgg tgaatcagag
    16561 aaagatcaga cttttgctaa attcgcaaaa gactttgcac attttgctaa tttcaccgta
    16621 ccgctctgtg acgtactata gtcggcaaac gtctcacctt gaggttaaaa aaatgagcaa
    16681 catcctgatt atcaacggcg cgaaaaaatt cgcccactcc aatggtcaac tgaacgacac
    16741 cctgaccgaa gtcgcggatg gcacactgcg cgacctcggg catgatgtcc gcattgttcg
    16801 cgccgacagc gactacgatg tcaaagcgga agtacaaaac tttctctggg ctgatgtggt
    16861 gatctggcag atgcctggct ggtggatggg cgcgccgtgg acagtgaaaa aatatattga
    16921 tgatgtattc accgaaggtc acgggactct gtatgccagc gatggtcgta cccgcaaaga
    16981 tccatcaaaa aaatacggtt ccggcggcct ggtacagggc aaaaaatata tgctttctct
    17041 gacctggaac gcaccaatgg aagccttcac cgaaaaagat cagttcttcc acggcgttgg
    17101 tgttgacggt gtgtacctgc cgttccataa agcaaaccaa ttccttggca tggaaccgct
    17161 gccgacattt atcgctaatg acgtgataaa aatgcctgat gttccccgct atactgaaga
    17221 atatcgcaag catcttgtgg aaatttttgg ttaactagag ctctggcttt agaaggagtt
    17281 aaccatgatt acagtaatcg cagaaattcg tactcgtcct ggtcaacatc accgtcaggc
    17341 agtgttggat cagtttgcta aaatcgttcc aaccgtactg aaagaagaag gttgccacgg
    17401 ctatgcgcca atggtggatt gcgctgctgg cgtgagtttc cagtctatgg caccggattc
    17461 tatcgtgatg attgagcagt gggaaagcat cgcgcatctt gaagcgcatc tgcaaacccc
    17521 gcacatgaaa gcatatagcg aagccgtaaa aggtgacgtg ctggagatga atattcgtat
    17581 cctgcagccg gggctttgac atttctaaaa agaggccggt gctgctaccg gtctcagccc
    17641 agattagcca ttctttcttc ccgttttcag tcctcgatgg aaatcgttaa ttcgcttaat
    17701 ggttttaacc gcacgctgcg gcactgcgga agctaccgac cagacaatca tttccagaca
    17761 caacaatacc gtaccatgta gcggcgtttt ccctttttca tccccgcgcg gaacatgaat
    17821 cacgatactg gcgtctttgc taaaacgtga atccagcgcg tttgtcagca aaataacagg
    17881 gatccccagc cgcctcgcct cacgaagcgt tgtcagccct tcccggtgcg cagatttttg
    17941 cgccatcatg atcagaacat cgccacgttg aagcgcgatc agttgctcgg caaggccaat
    18001 acccgtacgg tttagtgccg tggcaggcaa acctatgcgg ttgaatagtc gtgcggtata
    18061 gtccgccaga atacccgaag cgccaatgcc aaaaattgcg acttgccgtg cctgcaccaa
    18121 caacgctaca gcttgcgcaa gcgcgtggcg gttttcaggc tctgacagga cattacaggt
    18181 atacaaatgc ccttcaagaa caaagtcgat tgcggtgtta acatcgctcg tcaagttact
    18241 caccgtcgta gacatctttt cgctggaact aagggctgga ccaagccact gttccagagt
    18301 gcgtttcaga tcacgcagcc cggcaaaccc cagggcctgt atagccctga taactgtggc
    18361 atcggaagtg ttcaacgtgg ccgcaatttc catcgccgtt tgctcgagta ccacttcacg
    18421 atgctcatta atgtagctgg cgacaactct taacccaggc gttaactgac tcgcgcgagt
    18481 gcgaaaacgc tcaccaaaaa tatcaacccg cactttatct ttctggatca tttagcctcc
    18541 ggtagaggtc gccctgcaat ttgtgattgt atctgcgcag ccatcagccc cagagatgca
    18601 aaggagttag aaattgcctc ttcacgagaa atcagcacat aacgcccgga acgacaggca
    18661 gtcagaaact gacaccatcc cggcatgact ttttccattg ctgccagctc atcctgaggt
    18721 ttaccaccgg tgtcaccgcg ccaggttgca aaaacaaaat cggcatccag ttcaggtaaa
    18781 cgctccgcgc tcacatccat tcgcccacct tcaggaatgc tctcaatcag cggcggaaaa
    18841 cgaaaaccag catcgcgtaa tacccgtccc agcgaatgat agctatgcat cacattaatt
    18901 tttccctggt ttgcctgaat caccgatacc gttatttttt ggctgtccag cgtcgccttc
    18961 agcgcattga tttgtgcctg atagcggcgt tcaagtatcg ccagctgcga ctgcgttcct
    19021 gtaagttctg ccagcttgcg atagatttct ggcgcgcccc ctttgagatg atcaatgctc
    19081 accgtgggcg caattttttc aagttgttca atgggcgtat tacgggtcgg ttctgtgatg
    19141 atcaagtcag gctttgccgc cacaatcgct tcaatatcaa tatcagcggt accaataaag
    19201 gcgatcgatg aattatcaaa gtcgacacct gtcaataacg cgccagatcg aatgaaatgg
    19261 ctaccgtcag gccgagttcg cccgtggctg gcgacaggag gtacaccgag ctcaatcaga
    19321 ggaatagtga tatcaagatc gtgtaaagag acaattctct ttggatgagc aggaacagtg
    19381 actttgcgcc ctaaatcatc agtaaatacc tgaacaggtt ctgttgcacg ggaaaaaaat
    19441 gacaacagta tcagcagaga aaaaaataaa cgcatataac tcccgttaaa aactgttcct
    19501 gcgctgccag agcagtagta aaaaaaatgg tccaccaatc agtgagataa tgattccggc
    19561 aggcagttgc aaaggcaaaa aagccaaacg accaatgcta tccgccagaa taactaacaa
    19621 cgcccccgat accgcgctcc ccagcagtaa tgtcgtctgc ccgccacgta gaataaaacg
    19681 tgatatatgg ggtgctatca atccgacaaa accgatgtta ccaacacacg aaacgcagac
    19741 ggctgtcagg attatgggtg cggcgacacg taacaacgcc agacgagaac tattcacccc
    19801 taacccggtt gcaacctgat gaccaagcag agcgatatcc gcagtcctgg cggtgaacag
    19861 caataaaaga gcggctggca acatccaaca ggctgaaata ccgactaaca tccagttagc
    19921 tgcatgcagg cttcccgata accacatcaa tgcagtttgt acatctcgaa catctgcagt
    19981 ggtcataaat acaccgatac cggcggcgaa aaaccaggaa acaccaatac caatcagaac
    20041 aaatcgcggg cgggaaatat cgcgcgcaca aaaaatcacg attaaagcca ccaacaggcc
    20101 accagcaaga ccagccactg gacgccagaa cattcccagc attggaaact ggaaaatcag
    20161 ccacagcaca gccacgctac atccttcttt gacgccgatt aaaccaggat cggcaaggcc
    20221 gttacgtgca atggattgca ttgcggcccc tgccatacct aacatggccc cgcatagcaa
    20281 tgccatgatg actctcggca agcgaatatc ctgcacaata taacgtgcgt ctgtgcttac
    20341 gttttctgga gcaaacaacg ctcgtcctac ttccgatgcc ggaacagaga aagaaccctg
    20401 catcagaccg aatatcagta ttccaaccgc aagcaggaac agcccaccaa gcaacagcag
    20461 atttttaggg cgcaccagtg tcgaaaactt accaacacgt agtgggcgta gcccgacgtt
    20521 cattatccga ctcatttgaa catcctcgtc gccataatga caaaaacagg cgcaccaact
    20581 aacgccgtca tgacaccggt cgctaactca tggggcgtga aaagcgtccg ggcaataata
    20641 tctgccagta ataacaaaag cgcgccgaca caagctgaaa gagggagcag aacgcgcaga
    20701 tccgctgata ccagacgccg gacaatctgc ggtactagca ggccgacaaa accaatgggg
    20761 ccagcaatcg atacggctgc gccacagagc aacgcgatcg caagcagggt gaatgttcgc
    20821 gtgcggagta cagagacgcc cagcccctgc gccatgcgat cgcccagtgc caacatgtta
    20881 agggagggtg caaggtaaag ggctaacaca aatcccccca gagaaaacca ggcggacgta
    20941 cccagcgtcg cccaatcctg ccccgctaaa tcacctgcta gccatgtccg catcgccagc
    21001 agtgtttgtt cgtcaagaat caggattgca gccgttattg aggacacgaa cgccgatagc
    21061 gccacgccgc ataaagtaac tttcattggc gttaaccctg aacgccctgc ggaggaaagc
    21121 agcaatatca acaggaacaa taacgcgccc cccgtagatg ccagcagtgg gcgtccaacc
    21181 ggaaaggcca gtccaagcgc actggcggca acgacagcaa gagcggctcc ggcatttaag
    21241 cctaaaatat gtggttcccc caatgggtta cgaatgacag cctgcaacaa agcaccagca
    21301 acaccaagag aagcaccggt aagcaatgct gccgctaaac gcggcaaacg gagtcttaca
    21361 attacgttgt gatcgaagtt ttgcggatca aaatgaagaa atgcctgcaa caccgtttgt
    21421 ggtgcaataa atcgggcacc aatccctgga tataccacgc atcccaccag cagtaaggcg
    21481 aggaaaatta cagtaaccag ccctgtgcgc atcatacttt ttctacacca cgaaacggca
    21541 tgaagaacgg ctttcccgtc agaggattta ttgatgcgtg aacatcaacg tcaaagacag
    21601 cttttaccag ttcaggcgtg caatgctccc cctcattcaa cacacgcacc actttcccct
    21661 ggcgtaaaaa tatcaacgta tcgccataat tgacggcaaa attcagatca tgcaacacca
    21721 cgacgactgt acgcccgtga tgacgcgtta aatcatgtaa taactcaaga atttcaacct
    21781 gataacgtaa atcaagccag gttgtgggtt catccagcag gatataaggc gtcttttgcg
    21841 ccaacaccat cgcaatccag caacgctggc gctgcccacc agagagtttt tcaacaggta
    21901 aatgtgcaaa ctcctgcgta ccggttaatt tcagggcctc ttccaccgcc tgctcatcgg
    21961 cgtcgctcca ttgacgtatg aaattttgcc agggaaaacg cccacgcgac accagttcat
    22021 aaacggttaa gccctccggc aataatggcg actgcggcaa gatcccaagt ctacgggata
    22081 acgctttcgt tggttgctcg tgaatcgctt tgccatcaag caatatcgaa ccgcccatag
    22141 gttgcaagat acgtgcaatg gtgctgagca acgtcgactt tccacagccg tttgccccaa
    22201 ccagaacggt cattttttct gtgggaacgg agaaagaaac accatcaaca atgattttct
    22261 tgtgataccc ggcagaaaca ttgtcgagga tcagcccctg cccttttgcg ttatgtgcca
    22321 cgtgtacgcc aacttaatca aagacaaaca aaaataaaac tcattctcct ttgagagttt
    22381 gacgccacaa aatgtagtag tcaagcagtt aaaagccaca caaaaacaag gtaaataaca
    22441 ggtaaaatat ttttatacat aaaaataaaa acattaaata tcaataaatt aaaagcaatc
    22501 aaattgtata aacctttcat aaaaacacat gtagcaattt tttgttattt ctcatttact
    22561 actacattac tgcgtgattg aatgattctc aattacatat ccgatggcga aataacaaac
    22621 ggatagtgct tagtgagcaa taagaaacaa ttttcactcg cgacaatccg cgagtttttg
    22681 ggataacaga ctaaatggct atgttcacac cttcattctc aggactcaaa ggtcgggcgc
    22741 tcttttcact gctttttgcg gcaccgatga ttcatgcaac agactctgta acgaccaaag
    22801 atggcgaaac aatcactgtt acagcagatg caaataccgc aactgaggca accgatggtt
    22861 atcaacctct gagcacctct acggcgacat taaccgatat gccgatgctg gatatcccgc
    22921 aggtggtcaa tacggttagc gatcaggttc tggaaaacca gaatgcgaca acgctggatg
    22981 aggcgcttta taacgtcagt aacgtggtac agaccaatac attaggcgga actcaggacg
    23041 cctttgtacg ccgtgggttt ggcgcaaacc gggatggctc catcatgacc aacggtctgc
    23101 gaaccgtact tcctcgcagt ttcaacgccg ccacagaacg tgtggaagtg ctaaaaggcc
    23161 cggcctccac gctgtatggc attctcgatc ctggcggact gattaacgtc gtgaccaagc
    23221 gcccggaaaa aacattccat ggttcggttt cagccacctc ctccagtttt ggtggcggca
    23281 ctgggcaact tgatatcaca ggtcccattg aaggcactca gctggcgtat cgccttaccg
    23341 gggaagtgca ggatgaagat tactggcgaa acttcggtaa agagcgcagt acatttattg
    23401 ccccgtcact cacatggttt ggtgataatg caacagtaac catgctctat tcccatcggg
    23461 actataaaac tccgttcgat cgtggaacga ttttcgacct tacgacgaaa cagcccgtaa
    23521 acgttgatcg aaaaatacgt tttgacgaac cgtttaatat tacagatggt cagtccgatc
    23581 tggcgcaact caacgcagaa tatcatctca atagccagtg gacagcacgc tttgattaca
    23641 gctacagcca ggataaatac agcgataatc aggcgcgtgt taccgcatat gatgcaacga
    23701 caggaacact gacacggcgt gttgatgcaa ctcagggctc tacccagcgt atgcatgcta
    23761 ctcgtgcgga tctgcaaggg aatgttgata ttgccggatt ctataatgag attctgggtg
    23821 gggtgtcata tgaatattat gatcttctgc gtacagatat gattcgctgt aaaaaagcta
    23881 aagatttcaa tatttacaac cctgtttatg gtaataccag caaatgtaca acggtttcgg
    23941 cgtcggacag tgatcagacg atcaaacagg agagctactc agcgtatgca caggacgcac
    24001 tctatctgac cgataactgg attgccgtcg ccgggatccg ctatcagtat tacacgcagt
    24061 atgcgggtaa aggccgtcct tttaatgtca atactgacag ccgcgatgaa caatggactc
    24121 ccaaactggg gttggtctac aaactgacgc catcggtatc cttatttgcc aattattcgc
    24181 aaacatttat gccgcagtcg tcaattgcca gctacattgg cgatcttcca ccggaatcat
    24241 ctaatgctta cgaagtcggg gcaaaattcg agctattcga tggtatcacc gcagatattg
    24301 cgctgtttga tatccataaa cgtaatgtgt tgtataccga aagtattggt gatgaaacca
    24361 tcgccaaaac ggcaggccgt gttcgttcaa gaggggtaga agtcgacctt gcgggagcat
    24421 taactgaaaa cattaatatc attgccagct acggctatac cgatgctaag gttctggagg
    24481 atcctgatta tgcagggaaa ccattgccga atgttcctcg tcataccggt tcgctattcc
    24541 tgacctatga tattcataac atgccaggca ataatacgct gacatttggc ggtggtggac
    24601 atggtgtaag ccgtcgttcg gcaaccaatg gggctgacta ttatctgcca ggctattttg
    24661 ttgccgatgc cttcgccgca tacaaaatga aattgcagta tccggtcaca ctgcaattaa
    24721 acgtcaaaaa cctgtttgat aaaacgtatt acacctcttc catcgccaca aataatctgg
    24781 ggaatcagat tggcgatccg cgtgaagtgc aattcacggt gaaaatggaa ttttgatcaa
    24841 aaaagcccgg tatacacttg tataccgggc tatgttttat tcttctggcg ggaggattat
    24901 cagacctcaa tctctgccat gtcgcctttt tcttgcaacc agttgcggcg atcttccgag
    24961 cgtttcttcg ccagcagcat atccatcatc gcgtcagtac gctgatcgtc ttcatcatcg
    25021 atagtcaact gcaccagacg gcgagtgttc ggatcaagcg tggtttcgcg caattgcatc
    25081 gggttcattt ccccgagacc tttaaaacgc tggacgtttg gcttgccttt cttgcgtttt
    25141 aattgctcaa gtacgccctc tttctcttct tccgtcagcg cgtaataaac ctctttcccg
    25201 aggtcaagac ggtagagcgg tggcagtgca acgtaaacgt gaccgtgttt caccaatgcg
    25261 cggaagtgtt ttacaaacaa agcgcagagc agcgtggcaa tgtgcagacc atcggagtca
    25321 gcatccgcca ggatacagat cttgccgtaa cgaagctggc tcaaatcgtc gctgtcagga
    25381 tcgataccga tagctaccga aatatcgtgc acttcctgcg aagccagcac ttcgtcggaa
    25441 gagacttccc aggtgttaag gatcttacct ttcagtggca tgatcgcctg atattcgcga
    25501 tcgcgcgcct gcttggcaga tccgcctgcg gagtcacctt ccacaaggaa tagttcggta
    25561 cggttaagat cctgcgcggt acagtcagcc aatttaccag gcagcgccgg gccgctggtt
    25621 agctttttac gcaccacttt tttagccgca cgcatacgac gctgggcgct ggaaatcgcc
    25681 atctctgcca acagctccgc cgcctgaacg ttttggttca gccacaggat gaaggcatct
    25741 ttcaccacgc ccgaaacgaa tgccgcacac tgacgcgaag agagacgttc tttggtctgc
    25801 ccggcaaact gcggatcctg catttttact gacagcacat aggcgcagcg atcccagata
    25861 tcttccgccg acagctttac accacgcggc agaatgttgc ggtattcaca gaactcacgc
    25921 atcgcgtcca gcaggccctg acgcaggcca ttaacatggg taccgccctg catcgttggg
    25981 atcaggttga cgtagctttc ggtcagcagt tcaccgcctt ccggcagcca cagtagcgcc
    26041 cagtccaccg cttcagtatc gccagcgaaa ttaccgataa acggtttttc tggcagcgtc
    26101 ggtaaaccgt ttaccgcttc cgccaggtaa tcattcagac cgtcctgata gcaccagcgc
    26161 tgttcggtgt tgttgatctc atctttaaaa gtgatctcaa cgcccgggca cagtaccgct
    26221 ttggctttca gcacatgcgt caggcgtgaa acagaaaaac gcgggctgtc aaagaaggtt
    26281 tcatccggcc agaagtgcac gctggtaccg gtattgcgtt taccgcaagt gccgacaacc
    26341 tgtaaatctt gcaccttttc gccattttca aaggcgatgt tatagatctg accatcgcgg
    26401 cgtacgttaa cttctacgcg cttcgacagg gcgttaacta ccgaaatccc cacgccatgc
    26461 aggccgccag agaactggta atttttgtta gagaatttac cgcccgcgtg cagacggcaa
    26521 agaatcagtt caaccgccgg taccccctct tccgggtgaa tatctaccgg catcccgcgc
    26581 ccatcgtcaa tcacttctaa cgactggtcg gcatgtaaga ttacatccac gcgttttgcg
    26641 tggcccgcca gtgcttcatc gacactgtta tcaataactt cttgccccaa atggttaggg
    26701 cgagtggtat cggtatacat ccccggacgg cggcgaaccg gctcaagccc ggtgagtacc
    26761 tcaatggcat cagcgttata agtttgcgtc atggtttaag ttagcaattc gagttgatcg
    26821 tcagagatgg tgcagaccaa gaaaatcgac gatcgggttg aaataatctt cgaagcccgt
    26881 gaatgcgtgg ttgccgcctt ctatgacagt ctggcggcag gaagcgtagt acgccaccgc
    26941 ctggcggtaa tccagcactt catctcccgt ctgttgcagc agccagatca aatccggcgc
    27001 ttccagcggg tcaatctgca tgactttgag atcgtaaata tggcgtgact ctagcacata
    27061 ttgctgcccg gtgtaggggt tctcgttctg accgagatag tccgtcagca gttcaaacgg
    27121 gcgcaccgcc gggttgacca ccactgcggg cagcataaaa cattgcgaca accaggtggc
    27181 gtaatatccc cccagtgacg aaccgacaat acccagcgaa tcgccgccat gttccaggac
    27241 aatggattcc agcagttctg ccgcgtcgga aggatacggc ggcagctgcg gaatgatcat
    27301 ctcaacgtca gggtgatgtt ccgccagcca gttttttaac aagctcgctt ttgcagagcg
    27361 cggcgagctg ttgaaaccgt gtaaataaag aagcgtagac atcagtagcc ttctgaagcg
    27421 gtatcaggtt ggaagcgtgc gtccgccagg cgatgcacct cggtggtcag cgtgccatca
    27481 gcatgtaact caagagtacg ccagccgggc gcgatggtat ccagcgtaaa gttggaacag
    27541 tgcggcttaa actgcacaca ggtcgacggc gttgccagca ggcggcgacc gttccagtcg
    27601 agatccagct cctgatgaat atgaccgcac agcaagtatt tgacgtgcgg aaacttcgcc
    27661 agcacggtat ccagttcgcc cgcgttacgc aggctgtgtt gatcaagcca actacaaccc
    27721 gcaggtagcg gatgatgatg cagcagcagc aacgtatggc gttctggcgc atcggccagt
    27781 ttacgttcca gccactcaag ctgaaactcg ctcagctcac cgtgcggcac gccaaacacc
    27841 tggctatcca gcaacaggat ttgccattgc tcaccaataa acacccgctt cgccggggag
    27901 atacccgcat cctgtaacgc actgtacatc gcgggctgga aatcgtggtt gcccggcagc
    27961 cagacgcagg gcgcacgaaa acttgcgatg ccttcagcga aatgctgata ggccgcagag
    28021 gattgatcct gcgctaaatc acctgtcgcg acaatcaggt cgaattcgtg ctggtgtggc
    28081 cgaatcgcct ccagcaccgc ctggtagctt tcccaggtgt ttacccctaa cagggcttcg
    28141 tgcttttgtg caaacaggtg agtgtcggta atttgtaaaa tcctgactct ggcctcacca
    28201 gccagaggaa gggttaacag gctttccaaa tggtgtcctt aggtttcacg acgctaataa
    28261 accggaatcg ccatcgctcc atgtgctaaa cagtatcgca accagtccgc taaaaactga
    28321 ttaatttgat gcttttcgtc gcgttgatgc aactttttat taggataatc ataccgcgct
    28381 ttgaagcgaa aaatctgctg gcttgaacac acttcagcca ccatcgcgtc atgatacaga
    28441 cgcaccgtca ttgacggaag gctccagtaa ctgatcgcgg gcgcagtctg ttctattgtc
    28501 accagggtag tgtatcgggt cgattccaca atcgtcagcc gatattgtgc gtttgccacc
    28561 tgatagctta cagtttcgcc gggtgcgtca ttgcgcggta acaaacggcg caattgtgaa
    28621 aagttcatct cgcacaggcg catcatttca ggaaagtcag gtgtgtaacg cttcatttat
    28681 gcccactcat tttttaacgc ttgatgatgc agctgcagcc attgcaaagc gatgaccgac
    28741 gctgcgttgt cgattttccc ctcttctacc cactggtatg cctgttcccg gcttaccaca
    28801 tgaacgcgaa tatcttcgtt ttcatcagcc agaccgtgaa taccgcttgc ggtcgtggcg
    28861 tccacttcgc ccaccataat tgacgaacgc tcactggtgc cccccgggct tgccaggaaa
    28921 cttaacaccg gtttggtccg tttgactatc agtcccgcct cttcaatcgc ttcgcgacgg
    28981 gcaacatctt ccacactttc accctcttca atcatcccgg caaccatctc cagtagccaa
    29041 ggggtttcgc tggtgtcgta cgcggcaatc cgaatctgct caatcagcac aacttcatca
    29101 cgcactgggt caaagggtag caagactgcg gcgtgaccgc gctcaaaaat ttcccgccgt
    29161 acctcatgac tcatttgccc gttgaataga cgatgacgaa atctataaag atctaatgaa
    29221 aaaaagccgc gataaagtgt ttctcgtgca ataatttcta catcgttttt gccaaatgta
    29281 acgggcaggt tgtctggctt aagcattgtt aatgtcctgg cactaatagt gaattaaatg
    29341 tgaatttcag cgacgtttga ctgccgtttg agcagtcatg tgttaaattg aggcacatta
    29401 acgccctatg gcacgtaacg ccaacctttt gcggtagcgg cttctgctag aatccgcaat
    29461 aattttacag tttgatcgcg ctaaatactg cttcaccaca aggaatgcaa atgaagaaat
    29521 tgctccccat tcttatcggc ctgagcctct ctgggttcag ttcgttgagc caggccgaga
    29581 acctgatgca agtttatcag caagcacgcc ttagtaaccc ggaattgcgt aagtctgccg
    29641 ccgatcgtga tgctgccttt gaaaaaatta atgaagcgcg cagtccatta ctgccacagc
    29701 taggtttagg tgcagattac acctatagca acggctaccg cgacgcgaac ggcatcaact
    29761 ctaacgcgac cagtgcgtcc ctgcagttaa ctcaatccat ttttgatatg tcgaaatggc
    29821 gtgcgttaac gctgcaggaa aaagcagctg ggattcagga cgtcacgtat cagaccgatc
    29881 aacaaacctt gatcctcaac accgcgaccg cttatttcaa cgtgttgaat gcgattgacg
    29941 ttctttccta tacacaggcg caaaaagaag cgatctaccg tcaattagat caaaccaccc
    30001 aacgttttaa cgtgggcctg gtagcgatca ccgacgtgca gaacgcccgc gcacagtacg
    30061 ataccgtgct ggcgaacgaa gtgaccgcac gtaataacct tgataacgcg gtagagcagc
    30121 tgcgccagat caccggtaac tactatccgg aactggcggc gctgaatgtc gaaaacttta
    30181 aaaccgacaa accacagccg gttaacacgc tgctgaaaga agccgaaaaa cgcaacctgt
    30241 ccctgttaca ggcgcgtttg agccaggacc tggcgcgcga gcaaattcgc caggcgcagg
    30301 atggtcactt accgactctg gatttaacgg cttctaccgg gatttctgac acctcttata
    30361 gcggttcgaa aacccgtggt gccgctggta cccagtatga cgatagcaat atgggccaga
    30421 acaaagttgg cctgagcttc tcgctgccga tttatcaggg cggaatggtt aactcgcagg
    30481 tgaaacaggc ccagtacaac tttgttggtg ccagcgagca actggaaagc gcgcatcgta
    30541 gcgtcgtaca aaccgtacgt tcctccttca acaacattaa tgcttctatc agtagcatta
    30601 acgcctacaa acaagccgta gtttccgctc aaagctcatt agacgcgatg gaggcgggtt
    30661 actcggtcgg tacgcgtacc attgttgatg tgttggatgc gaccaccacg ctgtacaacg
    30721 ctaagcaaga gctggcaaat gcgcgttata actacctgat taaccagttg aatattaagt
    30781 cagctctggg tacgttgaac gagcaggatc tgctggcact gaacaatgcg ctgagcaaac
    30841 cggtttccac taatccggaa aacgttgccc cgcaaacgcc ggaacagaat gctattgctg
    30901 atggttatgc gcctgatagc ccggcaccag tcgttcagca aacatccgca cgcactacca
    30961 ccagtaacgg tcataaccct ttccgtaact gacgacgacg acggggcttc ggccccgtct
    31021 gaacgtaagg caacgtaaag atacgggtta tctgccgcat tcttccccct tctcgcttca
    31081 atttcgacca gccatcctct attctgatgg gtatttacca ctggtcccgg aagacaaaaa
    31141 tgaaacggac aaaatccata cgccacgcat cgttccgcaa aaactggagc gcacgccatc
    31201 tgacaccagt cgctctcgcg gttgccactg tttttatgct ggcgggctgt gaaaagagtg
    31261 atgaaacagt gtctctctat caaaatgctg acgactgttc agctgcaaac ccaggcaaaa
    31321 gcgccgaatg taccaccgcg tacaacaatg cgctgaaaga agccgaacgt actgcgccga
    31381 aatacgccac ccgtgaagac tgtgttgctg aatttggtga aggtcagtgc cagcaggcac
    31441 cagcccaggc tggcatggca ccagaaaacc aggcgcaggc ccagcaatcc agcgggagtt
    31501 tctggatgcc gctgatggcc ggttacatga tgggacgtct gatgggcggc ggcgcgggat
    31561 ttgcacagca gccgctgttc tcctcgaaaa acccggccag cccggcttac ggtaaatata
    31621 ccgacgcgac cggtaaaaac tatggcgcag cccagccagg ccgcaccatg accgtaccga
    31681 agacggcaat ggcaccaaaa ccggcgacca ctactactgt tacccgtggc ggttttggtg
    31741 aatctgttgc caaacaaagc actatgcagc gtagcgcaac cggcacctct tctcgttcaa
    31801 tgggtggctg ataccgatgg aaagagtcag tattaccgag cgcccggact ggcgcgaaaa
    31861 agcccacgaa tacggtttca attttcacac catgtacggc gagccgtact ggtgtgaaga
    31921 tgcttactac aagttgaccc tctctcaggt tgaaaagctg gaagaagtca ccgccgaact
    31981 gcaccagatg tgcctgaaag tggtggaaaa agtgatcgcc agcgatgagc tgatgaccaa
    32041 attccgcata ccaaaacaca cctggagttt tgtgcgccag tcatggctga cgcaccagcc
    32101 atcgctttat tcgcgtcttg atctggcgtg ggatggcact ggcgaaccta aacttctgga
    32161 aaataacgcc gatacgccaa cgtcactata cgaggcggcg ttctttcagt ggatctggct
    32221 ggaagatcag cttaacgccg gtaacttgcc ggagggcagc gaccagttta acagtctgca
    32281 agaaaagctg atcgatcgct tcgttgagct gcgtgaacag tatggcttcc agttgctgca
    32341 tctcacctgc tgtcgcgaca cggtggaaga tcgcggaacc attcagtatt tgcaggactg
    32401 cgcaacggaa gctgaaatcg ccaccgagtt cctctacatt gacgatatcg ggttaggtga
    32461 aaaaggtcag ttcacggatt tacaggatca ggtgatttcc aacctgttca agctgtatcc
    32521 gtgggaattt atgttgcgtg agatgttctc caccaagctg gaggatgcag gcgtacgctg
    32581 gctggaaccg gcgtggaaga gcattatctc caacaaagcg cttctaccgc tactgtggga
    32641 gatgttcccg aatcacccga acctgctgcc cgcttatttt gcggaagatg atcatccgca
    32701 aatggaaaaa tatgtggtta aaccgatctt ctcccgtgaa ggcgcaaacg tgtcgatcat
    32761 tgagaacggc aaaaccattg aagcagcgga aggtccgtat ggcgaagaag ggatgattgt
    32821 tcagcaattc cacccgttac cgaaattcgg cgacagctat atgctgattg gtagctggct
    32881 ggtgaacgat caacctgccg gaattggcat tcgtgaagac cgtgcattga tcacccagga
    32941 tatgtctcgg ttttatccac atatttttgt tgagtaatac agcttaatat tgccccgata
    33001 agcggggcaa tctct
//
LOCUS       DAPOXO010000059        32815 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPOXO010000059 DAPOXO010000000
VERSION     DAPOXO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32815
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.059"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(427..2097)
                     /gene="betA"
                     /locus_tag="ROH59_003167"
     CDS             complement(427..2097)
                     /gene="betA"
                     /locus_tag="ROH59_003167"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HDX4805614.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVITSKPGVNPLFEA
                     MIEAGMQAGYPRTDDLNGYQQEGFGPMDRTVTPHGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRAAANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFNIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPRIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPGILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGKEALPRSTAGYFVANGMPVRAKK"
     gene            complement(2111..3583)
                     /gene="betB"
                     /locus_tag="ROH59_003168"
     CDS             complement(2111..3583)
                     /gene="betB"
                     /locus_tag="ROH59_003168"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HDX4805615.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTD
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPTKCKAAFEQKVLARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGNVLKGDSFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSILIYESEDEVIRRANDTDYGLAAGIVTADLNLAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            complement(3597..4184)
                     /gene="betI"
                     /locus_tag="ROH59_003169"
     CDS             complement(3597..4184)
                     /gene="betI"
                     /locus_tag="ROH59_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308386.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HDX4805616.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAELRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD"
     gene            4313..6346
                     /gene="betT"
                     /locus_tag="ROH59_003170"
     CDS             4313..6346
                     /gene="betT"
                     /locus_tag="ROH59_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDX4805617.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKNLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     gene            7224..8312
                     /gene="pdeL"
                     /locus_tag="ROH59_003171"
     CDS             7224..8312
                     /gene="pdeL"
                     /locus_tag="ROH59_003171"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator/c-di-GMP
                     phosphodiesterase PdeL"
                     /protein_id="HDX4805618.1"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGNNSHKYINDN
                     HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGMIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     gene            complement(8354..9286)
                     /locus_tag="ROH59_003172"
     CDS             complement(8354..9286)
                     /locus_tag="ROH59_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4805619.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFHAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMAQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHRES"
     gene            complement(9378..9875)
                     /locus_tag="ROH59_003173"
     CDS             complement(9378..9875)
                     /locus_tag="ROH59_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDX4805620.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALAAGWLASVSGISGFWASVITTVPFSAVV
                     VWQGRFGLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATT
                     KRDGY"
     gene            10133..10738
                     /locus_tag="ROH59_003174"
     CDS             10133..10738
                     /locus_tag="ROH59_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HDX4805621.1"
                     /translation="MTIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLANTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLKLARERGFEEIAQLLIAAGA"
     gene            10778..11641
                     /locus_tag="ROH59_003175"
     CDS             10778..11641
                     /locus_tag="ROH59_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDX4805622.1"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFNGLFRHDDKVQFDDQGITIGQHHHIEMSHCQRWLSPTLQMTAV
                     NFHLIAWQQWYDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLVLILFISGHPAEKYKEEFYLGLQRGRNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     gene            11631..13178
                     /gene="fdrA"
                     /locus_tag="ROH59_003176"
     CDS             11631..13178
                     /gene="fdrA"
                     /locus_tag="ROH59_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDX4805623.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGVDNEQLLAEIEELFNTKAQSGSHEARYG
                     TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAISMLENDPQTEIIVLISKPPAPAVARKVLERARACRK
                     PVVACFLGRGETPVDEQGLQFARGSKEAALKAVMLSGVKQEHLDLHTLDQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETLFAVMEKHGDVYSNIQPDPEFRLQDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            13178..14596
                     /locus_tag="ROH59_003177"
     CDS             13178..14596
                     /locus_tag="ROH59_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDX4805624.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKITAANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
                     PPVTWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     gene            14749..15699
                     /locus_tag="ROH59_003178"
     CDS             14749..15699
                     /locus_tag="ROH59_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HDX4805625.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSESQRDELQKANPDWRFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQDGKEVIITTPECLPAALRGETGTHIIKT"
     gene            15709..17091
                     /locus_tag="ROH59_003179"
     CDS             15709..17091
                     /locus_tag="ROH59_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDX4805626.1"
                     /translation="MKENNSRREFLSQSGKMVTAAALFGTSVPLAHAGVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKQHPDAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQTGFECEIVAFP
                     QHGLLLSKSESLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELAHRMAAQRISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     gene            17468..18517
                     /gene="yahK"
                     /locus_tag="ROH59_003180"
     CDS             17468..18517
                     /gene="yahK"
                     /locus_tag="ROH59_003180"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HDX4805627.1"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPHDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSESKREAAKALG
                     ADEVVNSRNADEMVAHVKSFDFILNTVAAPHNLDDFTTLLKRDGTITLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            19140..19384
                     /locus_tag="ROH59_003181"
                     /pseudo
     CDS             19140..19384
                     /locus_tag="ROH59_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(19401..20072)
                     /locus_tag="ROH59_003182"
     CDS             complement(19401..20072)
                     /locus_tag="ROH59_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HDX4805628.1"
                     /translation="MMKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYIFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLTSIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            20219..20494
                     /locus_tag="ROH59_003183"
     CDS             20219..20494
                     /locus_tag="ROH59_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX4805629.1"
                     /translation="MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVASQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            complement(20595..22181)
                     /gene="prpR"
                     /locus_tag="ROH59_003184"
     CDS             complement(20595..22181)
                     /gene="prpR"
                     /locus_tag="ROH59_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HDX4805630.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFSRHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGQFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKMSLAALSVPFSAALRQGLETCQILLLHYDWPGNIRE
                     LRNMMERLALFLSVESTPDLTPQFLQLLLPELARESAKTPIPGLLTAQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            22420..23310
                     /gene="prpB"
                     /locus_tag="ROH59_003185"
     CDS             22420..23310
                     /gene="prpB"
                     /locus_tag="ROH59_003185"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HDX4805631.1"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNILRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDDLFARGQVK"
     gene            23470..24639
                     /gene="prpC"
                     /locus_tag="ROH59_003186"
     CDS             23470..24639
                     /gene="prpC"
                     /locus_tag="ROH59_003186"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HDX4805632.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEIFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ"
     gene            24673..26124
                     /gene="prpD"
                     /locus_tag="ROH59_003187"
     CDS             24673..26124
                     /gene="prpD"
                     /locus_tag="ROH59_003187"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HDX4805633.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSRVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPVFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI"
     gene            26164..28050
                     /gene="prpE"
                     /locus_tag="ROH59_003188"
     CDS             26164..28050
                     /gene="prpE"
                     /locus_tag="ROH59_003188"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HDX4805634.1"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDREVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            28375..29634
                     /gene="codB"
                     /locus_tag="ROH59_003189"
     CDS             28375..29634
                     /gene="codB"
                     /locus_tag="ROH59_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDX4805635.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     gene            29624..30907
                     /gene="codA"
                     /locus_tag="ROH59_003190"
     CDS             29624..30907
                     /gene="codA"
                     /locus_tag="ROH59_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="HDX4805636.1"
                     /translation="MSNNALQTIINARLPGKEGLWQIHFHDGKISAIDAQSGVMPVTE
                     NSLDAEQGLVLPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTKPAQTTVYLEQPEAIDYKR"
     gene            complement(31028..31639)
                     /gene="lacA"
                     /locus_tag="ROH59_003191"
     CDS             complement(31028..31639)
                     /gene="lacA"
                     /locus_tag="ROH59_003191"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HDX4805637.1"
                     /translation="MNMSMTERIKAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEF
                     EKRESLIKEMFATVGENAWVDPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGCHVVINPGITIGDNSVIGA
                     GSVVTKDIPPNVVAAGVPCRVIREINDRDKQYYFKDFKVESSV"
     gene            complement(31705..>32815)
                     /gene="lacY"
                     /locus_tag="ROH59_003192"
     CDS             complement(31705..>32815)
                     /gene="lacY"
                     /locus_tag="ROH59_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HDX4805638.1"
                     /translation="FAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFI
                     FIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSHFEFGRARMFGCVG
                     WALCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAF
                     SLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTT
                     MGELLNASIMFFAPLIINRIGGKNALLVAGTIMSVRIIGSSFATSALEVVILKTLHMF
                     EVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAY
                     LVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA"
BASE COUNT         7938 a         8314 c         8783 g         7780 t
ORIGIN      
        1 agcgataatc ttgtgctaaa aaatatttaa gcatgatgat taattaaaga agagtaaaaa
       61 taaatcactg ctaataaatt atacgaatcg tgtttaaagc tccatgtggt tttggtctga
      121 cttatttttg tactcgttac aagaaccctt ttcgtatatg ctaaccgtga gcgggaatga
      181 acaggtaacc atagccagga acattagcgg cgtaattctt aagctgagtg gtatttcatc
      241 tgtagtttat ctgtgtatgc atagcacatt catcagccag attgagcaag tcagcttaga
      301 atttgctggc gagattgtca cgatgaagca tgagagttac ctcagtgttt tatataagga
      361 ttcggtcctc atagtagaac ggtaactctc aatctgatag gttcctgagt cagttcacat
      421 cacgactcat tttttcgctc tcaccggcat cccatttgcc acaaaatatc ccgccgtgct
      481 cctcggcaac gcttccttcc cacgaatcat atccgctatt ttctcgccaa tcataatcgt
      541 cgtggcgttc aaattgccgg tgataatttg cggcataatt gacgcatcca ccacgcgcag
      601 gccttccagc ccgtgtacgc ggccttcgcc gtcaaccaca gccatctcgt cataacccat
      661 tttgcaggta ccgcacggat gaaacgcggt ttcggcgtgg ttacgcacga actcatcgag
      721 ctgctcatcc gtctggcatt cgacaccagg gctgatttcg cggccacggt attgatccag
      781 cgcgggttga tgcatgatct cgcgtgtgat gcgaattgcg tcgcggaact cctgccagtc
      841 ctgctcgtgc gacatgtagt taaacagaat tcccggatgc tggtgcgggt cgcgggattt
      901 aatccgcaca tgcccacggc ttggcgagcg catcgatccg acatggcatt ggaagccgtg
      961 ctctttcact gcgttcgagc cgttatagtt aatcgccact ggcaggaaat ggtactgaat
     1021 attcggccac gcaaattcct cacggctgcg aataaatccg cctgcttcaa agtggttgct
     1081 ggcaccaacg ccggtgccgc caaacagcca ctccgcaccg attctcggct gattccacca
     1141 ctgcagggca gggtagaggg aaaccggttc tttgcactcg tattgcagat acatctccag
     1201 gtgatcctga agattttcgc cgacgccggg taattcatgc accagcggaa tattaaactc
     1261 cgccagcagt tcagcgttgc cgacgccgga gcgttgcagg atctgcggtg aagcaatcgc
     1321 gcctgcacat aacagcactt ctttattcgc cgccgcgcgg gtcggaatag tgctgtcgcc
     1381 ttccagccac tcgacgccca ccgcgcgttt gccgtcaaaa atgatgtgat cggtcatggc
     1441 gtgagtacga atggtcaggt tagggcgcga tttggcctga tcgagatagc cacgcgcggt
     1501 gctggcgcga cggccatgcg gcgtgacggt gcgatccatc gggccaaaac cttcttgctg
     1561 atagccgttg agatcgtccg tgcgtgggta gcctgcctgc atgcccgctt caatcatcgc
     1621 ttcaaacagc ggattgacgc cgggtttgga ggtgatgacg ctcaccgggc catcgccacc
     1681 gtggtaatcg ttctcgccca catcgcgagt ctcggccttg cggtagtagg gcaggcagtc
     1741 gagataactc cagttctcca gaccaggttc ttgtgcccag ttatcgagat ccagcgcatt
     1801 gccacggatg tagcacatac cgttgatcag cgatgaaccg cccagacctt tgccgcgtcc
     1861 gcactccatg cggcggttgt tcataaacgg ttcgggttcc gtctcatagg cccagttgta
     1921 gcgtttgccc tgtagcggga acgccagcgc ggcgggcatc tgggtgcgga agtcaaagcg
     1981 atagtccggg ccgcctgctt caagcagcag cacggttgtg ttcggatctt cagtcagacg
     2041 ggtagcgaga acgttgccgg ctgagccggc accaataatg atgtagtcaa attgcaaata
     2101 aacctcctgg ttagaatatg gactggaatt tagccatctc aacctggatg gacttcacct
     2161 gggtgtaact ctggagcgtc atcacgccgt tctcgcgacc aatgccggag tgtttgtagc
     2221 cgccaacggg catctctgcc ggggattcgc cccaggtgtt gatccagcaa atacccgctt
     2281 ccagctgatg aatgacgcga tgcgcgaggt tcaggtccgc cgtcacgata cccgccgcca
     2341 gaccgtagtc ggtatcgtta gcgcggcgaa tgacttcgtc ttccgactcg tagatcagaa
     2401 tggacatcac tggcccgaaa atctcttctc gcacaatggt catatcgtcg ctgcaatcgg
     2461 tgaacacggt cggtgcaacc catgcgccgt tatcgaagct atcccccttc agtacattgc
     2521 cgccgcacag tacgcgcgcg ccttcctctt tgcctttggc gatatagcgc agcacgttat
     2581 cgcgatgcgg gaagctgacc agcgggccga agttagtttg cggatcgaaa acgtcgcccg
     2641 cgcgaatgcg ctcaacgcgc gccagaacct tttgttcaaa tgcggctttg catttcgtcg
     2701 gaacgaagac gcgagtgccg ttggtacaca cctgaccgga gctgaagaaa ttcgccatca
     2761 tggcgatatc ggcggcgaga tcgagatccg catcgtcgaa aacgatcagc ggtgatttac
     2821 cgcccagctc catggtcact tctttcaggg aggaagctgc cgagttagcc atcacttttt
     2881 tgccgctggc gacaccgccg gtaaatgaca ctttggcaat gcccggatga tcggtcagat
     2941 attgtccggt ctccgcgccc acgcccggca acacgttaaa tacgccgtcc ggcaggcccg
     3001 cttcgctgta aatttcggcc agctttaacg cggtaagcgg ggtgacttcg ctcggtttga
     3061 aaatcattgc attgcctgcc gccagcgctg gggcggattt ccacaaagca atctggatcg
     3121 ggtagttcca tgcgccaatc cccgccacca cacccagcgg ttcgcggcgg gtataaacaa
     3181 atgacgtctc acgcaacggg atctggctgc cttccagcgc cgggatcagc ccggcatagt
     3241 actccagcac gtccgcaccg gtaacgatat cgacggttga ggtttccgaa tatgcttttc
     3301 cggtgtcaag ggtttccagt tttgcgagtt cgtcattgcg ttcacgcaga atatcaacgg
     3361 cccgacgcag aatacgcgag cgctccatag cggtcatcgc cgcccagatt ttttgccctt
     3421 gttgggcact cttcacggcg cgatcgacat cctcacgccc ggcggcctgc acggtcgcca
     3481 gcacgttacc gttggccggg ttaatggtct cgaaggtgcg accgctggtg gcggaggtat
     3541 aaccaccatg tatataaagc tgctgttctg ccattcggga catcacgtct cctcggttaa
     3601 tcggtgggta aatgctgagt aataaagtga cgggtcagcg agtgtgcgag aggtttatcc
     3661 agcggtttgc cgctcagtgc cgcgcgcagc cataatccgt caattagcgc ggcaaggccg
     3721 tagcccgctt cctgtgcctg ttggcgcggt aactcgcggc gaaattcgct caccagattc
     3781 gacaataagc ggcggctact gacctgctgc aaacggtaaa gcatcggctg atgcatactg
     3841 ctggcccaga aggccagcca ggctttcatc gccgcactgc tcacctgggt ttcatcgaag
     3901 tttccgccaa caatcgcctg taatcgcagc tctgcactgc cctgcggaag tgcatgtaat
     3961 cgattcaaaa ccgcgtcacg cagctgactg gtgatatcgc gcatggttgc ttccagcaga
     4021 ccatttttgt ccctgaaata gtggctgatg atccccgtag aaacgcctgc acggcgggcg
     4081 atctgcgcga tcgttgcatc gtgcatgccc acttcattta ttgcttccag cgtggcgtcg
     4141 atcagttgtc tgcgccggat cgactgcatt cccaatttgg gcattttcgc cactccattc
     4201 atcagcgttg tttatctatt aaagcggtta ttgattggac gttcaatata aaatgtgtct
     4261 taattgttac taatttgatt ttaaatggta acaataacag tggggatact ggatgacaga
     4321 cctttcacac agcagggaaa aggacaaaat caatccggtg gtgttttaca cttccgccgg
     4381 actgattttg ttgttttccc tgacaacgat cctgtttcgc gacttctcgg ccctgtggat
     4441 tggccgcacg ctggactggg tttctaaaac cttcggttgg tactatctgc tggcggcaac
     4501 gctctatatt gtctttgtgg tctgtatcgc ttgttcgcgt tttggttcgg tgaagctcgg
     4561 gccagaacaa tcaaaaccgg aattcagttt gctgagttgg gcggcgatgc tgtttgctgc
     4621 cgggatcggt atcgacctga tgttcttctc cgtagccgaa ccggtaacgc agtatatgca
     4681 gccgccggaa ggcgcgggac agacgattga ggccgcgcgt caggcgatgg tctggacgct
     4741 gtttcactac ggcttaaccg gctggtcgat gtatgcgctg atgggcatgg cgctcggata
     4801 ctttagctat cgttataatt tgccgctcac catccgctcg gcgctgtacc cgatcttcgg
     4861 taaacggatt aacgggccga taggtcactc agtggatatt gctgcggtga tcggcaccat
     4921 cttcggtatt gccactacgc tcggtatcgg tgtggtgcag cttaactatg gcttgagcgt
     4981 gctgtttgat attcccgatt cgatggcggc gaaagcggca ctgatcgcct tgtcggtgat
     5041 catcgccact atctcggtga catccggtgt cgataagggc attcgcgtgt tatcggaact
     5101 caacgttgcg ctggcgctgg gattgattct gttcgtgttg tttatgggcg acacctcgtt
     5161 cctgcttaat gcactggtgc tgaacgttgg cgactatgtg aatcgcttta tgggcatgac
     5221 gctcaatagt tttgccttcg accgtccggt tgagtggatg aataactgga cgctcttctt
     5281 ctgggcatgg tgggtggcat ggtcgccgtt tgtcggcttg ttcctggcgc gtatctcgcg
     5341 tgggcgtacc attcgccagt tcgtgctggg cacgttgatt attccgttta ccttcacgct
     5401 gttatggctc tcggtattcg gcaatagcgc gctgtatgaa atcatccacg gcggcgcggc
     5461 atttgccgag gaagcgatgg tccatccgga gcgcggcttc tacagcctgc tggcgcagta
     5521 tccggcgttt acctttagcg cctccgtcgc caccattact ggcctgctat tttatgtgac
     5581 ctcggcggac tccggtgcgc tggtgctggg gaatttcacc tcgcagctta aagatatcaa
     5641 cagcgacgca cccggctggc tgcgcgtctt ctggtcggtg gcgattggcc tgctgacgct
     5701 aggcatgctg atgaccaacg ggatatccgc gctgcaaaac accacggtga ttatgggcct
     5761 gccgttcagc tttgtgatct tcttcgtgat ggcggggttg tataaatctc tgaaggtaga
     5821 agattaccgc cgtgaaagtg ccaaccgcga taccgcaccg cgaccgctgg ggcttcagga
     5881 tcgcctgagc tggaaaaaac gtctctcgcg cctgatgaat tatccgggca cgcgttacac
     5941 taaacagatg atggagacgg tctgttatcc ggcaatggaa gaagtggcgc aggaactgcg
     6001 gttgcgcggc gcgtacgtgg agctaaaaaa cctgccgccg gaagagggac aacagttggg
     6061 gcatctggat ttgttggtgc atatgggcga agagcaaaac tttgtctatc agatttggcc
     6121 acagcaatat tcggtgccgg gctttaccta ccgcgcacgt agcgggaaat cgacctacta
     6181 ccggctggaa accttcctgt tagaaggcag ccagggcaac gacctgatgg actacagcaa
     6241 agagcaggtg atcaccgata ttctcgacca gtacgagcgg caccttaact ttatccatct
     6301 ccatcgtgaa gcgccgggcc atagcgtgat gttcccggac gcgtgattgt tattgcataa
     6361 aaccgcgcca tgtctgcata tggcgcggtt tctcttacct cttgatacgt tatatctgtg
     6421 tacagttaag cccttagtat cgattgatga ttgccaggca acagataata aaaaagaaaa
     6481 gaactattga agcccaaaac ctacgcttgg actgttgtga atgttcaata agcttagtct
     6541 tatttaatgt aaatattggt gctaatttga aatgacgctt tattcatggg aaacgcgtag
     6601 cgcaaatcaa ccaaaatcaa tgtaaccgtt tgttgtttaa ggtttaattg tctgtgtctg
     6661 atattttatt gattgtttta aatattgttt ttattgtcat tgttataatg ttggctatct
     6721 attgctgaat ggattcagtc ttaaaaagca ggttgttaag ggattagcat agagtaatga
     6781 cgtgtatgca taaccaacat ctttactcat tatgtcattg aatgttgacg ctatgtgttt
     6841 atgaggttga ggtattttca gttgatctgg attgttaaat tcatataatg cgcctttact
     6901 catgaatgga cgtcaatacg tagtgggaaa ttataaatat cgaaatagtc caactacttc
     6961 tttattacca aaaatgagta tctgaatttt aatattgcat tcttgcgtga ttatctcctg
     7021 agtttgactt gtgattacct ttttaaggta tttagcgtaa ctgtttttga gcgagcatca
     7081 gaggtaaaga taatcttctt gatagtgatg tgggatgtta tacgtatggc atcgctaatg
     7141 tttatggtta ccccttatgt gtgctcagga atccacaggt aatcactcat actgaacagc
     7201 gataaaagat aaaaggtgtg ttcatgaatt catgtgattt tcgtgttttt ctgcaagagt
     7261 tcggtacaac ggttcatttg tcattgcctg gtagcgtatc cgagaaagaa cgactgctac
     7321 tcaagctgct gatgcaggga atgtctgtaa cagaaatatc acagtacaga aatcgcagtg
     7381 caaagaccat ttcacatcaa aagaaacagc tctttgagaa actggggatt cagagcgata
     7441 ttactttctg gcgggatatt ttctttcagt acaatccgga gatcatatcc gccacgggta
     7501 ataatagtca caaatatatt aatgataatc actatcacca tatcgtcacg cctgaagcca
     7561 tcagtctggc gttggaaaac cacgagttta aaccgtggat ccaaccggtt ttctgcgcgc
     7621 agactggggt actgacgggc tgtgaagtgc ttgtccgctg ggaacatcca caaacgggaa
     7681 tgatcccacc ggatcagttt attcctctgg cggagtcatc cggtcttatt gtcataatga
     7741 ctcgccagct gatgaaacag actgcggata ttctgatgcc ggtaaaacat ttgctgccgg
     7801 acaatttcca tattggtatc aacgtctcgg cgggctgttt tttggctgcg ggatttgaaa
     7861 aagagtgtct gaacctggtt aagaaattag gtaacgataa aatcaagctg gttcttgagt
     7921 tgactgaacg taatcctatt ccggtaacgc cagaagccag agcgatattt gacagccttc
     7981 atcagcacaa tattactttt gcgctggatg actttggtac gggttatgcg acctatcgtt
     8041 acttgcaggc gttcccggtc gattttatta aaattgacaa gtcgtttgtg caaatggcga
     8101 gtgtcgacga aatctccggt catattgtgg acaatattgt cgaactggcg cgtaagcctg
     8161 gtttgagtat cgtggcggaa ggggtagaaa cccaggagca ggcggattta atgatcggca
     8221 aaggcgttca ctttttacag ggctatttgt actctccgcc agtaccgggt aataaattta
     8281 tctctgaatg ggtaatgaaa gcaggtggtt gatgtaaacc gctattcaca gcgcatcggg
     8341 aggttggcag cgattaactc tcccgatgca gtaaatcctg atagatcccc gttaatatgc
     8401 catttggcgc aaattgtttt ttaatccact gcgtcacctg accggtggca gagtgctggg
     8461 ttgcgagtaa catgcgtgaa tcctggcgcg ggttatggat ttgtcgggta accagcaagg
     8521 attgcgccat cgcctcacgg accatgtaat ccggcaaaaa accaattcct tcacctaaaa
     8581 tctggcactg acatttggtg ttgaaatcgg gcaccagaat cgattcctgc ccatgcagca
     8641 accagcctac ttttttatta atcgtatgcg cggtgtcctc caccatgata ttagggtaga
     8701 gacgcagctg gctttcggcg atcggctccg gcacaaaggc taatggatga tccggagcga
     8761 tggcaaaagc ccagcgaatc gcgccaatct ccgtgtaatc aatgccgcca ccgtccagca
     8821 gcgtgtcggg tgcgccgata gcgatatttg cctgattatt aataatcgca tcccagacgc
     8881 cgttatacac ttcggtggtg acggtaatct ggcaggtagg aaactgcttt ttcagcacct
     8941 gtaataagcg tgcggtgtgt ttgggcgtat aaagcagctg attaatacaa atgcgcacac
     9001 gcgcttctat gccctgcgaa atagtatcga tactgcgttt aatggcgtga aaatcattca
     9061 gcaggtcggt agctttgcgg aaaaaataac gcccggactc cgttaactca atgctgcggg
     9121 tactgcgagt gaacagcacc acatccagcc ctgtttccat tcgcttgatg gtgtagctaa
     9181 tggcggaagt ggttaaaccc aactcttctg cggctttact gaagctgcca aaacgtgcag
     9241 cggtagtaaa tgccaacaga ttctcttcgg taaaaattga gttcattaaa ccattcccgc
     9301 cattatcgaa tatgaatttc tccagccatg actgtagagg tatcggttaa agatagataa
     9361 tcatttttga ataactttta atacccgtcg cgtttagtcg tcgcttcgct taatttttgt
     9421 cctccatatt ctgaaattat ccccacgcag ttacccgcca gaaaacccag taatgtcacc
     9481 gtccagttca tcccgctggc aaaaaatagc gtcatgccga gaaagcctcc gggaataaaa
     9541 gacaataaac cgaaacgtcc ttgccagacc actaccgctg agaaaggcac ggtagtaatc
     9601 acgctcgccc agaacccaga aatcccactc accgaggcca gccaaccggc agccagcgcg
     9661 gcgaaaaatg cccacaccat cccggaataa ttaaccgcca gacttctgat aaaccccgat
     9721 ttaccgccgc ctgcggcata aaaactgcaa aaggcgacga agccaatggt tcctaataat
     9781 tcccatccct gagagagccc gacatgtgaa gacactaact gccaaagccc tgcacaaata
     9841 ccgacggtga cacccgttgc cgtgagtccg ttcatcttgt tcccctctgg ttagacatgg
     9901 acaaaagcta ctcttacatg tgcagactat agagaaataa aacctgattg agtgaaaggg
     9961 tatcgggtca aagaaacaaa tattgcacta ccgcacactg cgaaaagatt gttgaacatc
    10021 attcaacaaa aaggcgaaat acggcgaatt aaatttaagc gggttctttt atcagattat
    10081 cgttgctatt ctcaattcat cgaaaacagc cacaaaaacc aggggaatgt gaatgactat
    10141 aaaaaatcta cctgccgact atttattggc tgcgcaacag ggtgatatcg ataaagtaaa
    10201 aacctgcctt gcgctgggtg tcgatattaa tacctgcgat cgtcagggga aaacggcaat
    10261 tacgctggca agtttatatc agcaatatgc ttgcgttcag gcattaattg atgccggagc
    10321 ggatattaat aagcaagatc atacctgttt aaatcctttt ttaattagct gtctgaacga
    10381 tgatttaacg ctactacgaa ttattttacc ggctaaaccc gatcttaatt gcgtaacccg
    10441 ttttggcggt gtcggcctga cgcctgcctg tgaaaaaggc catttaagta ttgtaaaaga
    10501 gcttttggca aatacggaga ttaacgttaa ccagactaac catgttggct ggacaccgtt
    10561 gctggaagcg attgtgctta atgatggtgg gattaaacag caggcgattg tccagttatt
    10621 gctggaacac ggtgccagcc cgcatctgac cgataaatat ggcaaaacgc cgctgaaact
    10681 ggcgcgggaa cggggctttg aagagattgc gcagttgctg atcgccgcag gtgcataaac
    10741 cgggaggctt gttatcaaca caccagaaaa acggtgtgtg tgggcgctaa ctgcggatgc
    10801 tgattttctg gcgcagcggg ggcaaggaca ggttgaacag gtctttgcca gagcggtaaa
    10861 tatcgcactc ccggctcgcc agcagttgct gacgctgctt tgtgaagagt acgacaatgc
    10921 gcctaacagt tgtcggttgg cactcactca ctttaatggt ctgttccggc atgatgataa
    10981 ggttcagttt gacgatcaag gcattacgat tggtcaacat catcatatag agatgagtca
    11041 ttgccagcgt tggctgtccc caaccttgca aatgaccgct gtgaattttc accttatcgc
    11101 ctggcaacag tggtacgaca ttattcatca gcacctgggg gaaaatgaaa ccctgtttaa
    11161 ttatcgcggc gataatccgt tttatcaggc gttaaataaa gaactacata ttaaacgacg
    11221 ggcagttatt caggccgtaa acgataaaca aaatatcgcc tcagcagtcg ccagtatgat
    11281 ggggttaggg attggcctta cgccatcagc cgatgattat ctgaccggac tggtacttat
    11341 tttatttatt tccggacatc cggcggaaaa atacaaagag gaattttatc tcggcctgca
    11401 acgcggcaga aataatacca cgttattaag tgccatcacg ctggaagccg cattacaaca
    11461 acgctgccgg gaaaatattc atcgttttat tcacaacatt atttatgaca tccctgggaa
    11521 cgcaactcag gcaatagaaa aaattaaaca tattggctcc agttccggct gcgacatgct
    11581 gtatggcatg gccgatggtt gtgcgctgag tcaaacctac ggagggaatt atgtcagtta
    11641 aaatagtcat taaaccgaat acctattttg attctgtctc gctgatgtct atctccacgc
    11701 gtgcaaataa actcgacggc gtcgagcagg catttgtggc gatggcgacc gaaatgaaca
    11761 aaggcgtgtt gaagaattta ggactgctga cgccggagct ggagcaggcg aaaaacggcg
    11821 acctgatgat tgtcatcaat ggtaaatcgg gtgtggacaa cgagcagttg ctggcggaga
    11881 ttgaagaact gttcaacacc aaagcgcaaa gcggctcgca cgaggcgcgt tacggcacta
    11941 ttgccagcgc caaaaagcat atcccggaaa gtaacctggc agtgatttcg gtcaacggtc
    12001 tgtttgccgc tcgcgaagcg cgtcaggcgc tgcaaaatga cctcaacgtg atgctgtttt
    12061 ccgataatgt ctcagttgaa gatgaactgg cgctcaaaca gttggcccat gaaaaagggc
    12121 tgctgatgat ggggccagac tgcggcacgg cgattatcaa cggcgcggcg ctctgctttg
    12181 gtaacgccgt gcgtcgcggc aacatcggta ttgttggcgc atctggcacc ggcagccagg
    12241 aattgagcgt ccgtatccat gaatttggtg gcggcgtttc acaactgatc ggcaccggcg
    12301 ggcgcgacct gagcgagaaa atcggcggac tgatgatgct cgatgccatc agcatgctgg
    12361 aaaacgatcc gcaaactgaa atcattgtgc ttatctccaa accgcctgcg cctgcggtgg
    12421 cccgcaaagt gctggaacgc gcacgcgcct gccgcaagcc agtggtggcc tgcttcctcg
    12481 gtcgtggcga aacgccagtg gatgagcagg ggctacagtt tgctcgcggc agcaaagagg
    12541 cggcattgaa agcggtgatg ctctccggcg tgaaacaaga acatctcgat ctgcatacgc
    12601 ttgaccagcc gttgattgcg gatgtgcgcg cgcgtctgca accgcagcag aaatacattc
    12661 gtggtctgtt ctgcggcggt acgctgtgtg acgaaaccct gttcgcggtg atggaaaaac
    12721 atggcgatgt ctacagcaat atccagcccg atcctgaatt ccgcctgcaa gatatcaacc
    12781 gcagcatcaa acacaccttc ctcgactttg gcgatgatga cttcaccaac ggcaagccgc
    12841 atccaatgat tgacccgacc aaccgtatca gccgcttgat cgaagaagcg cgcgatccag
    12901 aagtggcggt gatcgtgatg gattttgtgc tcggatttgg atcgcatgaa gatccggtcg
    12961 gttccaccat cgaggcgatc aaagaagcga aagcgatcgc cgctgccgaa ggacgcgagt
    13021 tgatcattct cgcctatgtg ctgggcaccg atctcgatac gccatcatta gaacaacaaa
    13081 gccagatgct gcttgatgcc ggagtgattc tggcgagcag cagcaccaat accggattgc
    13141 tggcgcgtga atttatctgc aaaggggagg aagcctgatg agccagtcac tgtttagcca
    13201 accgttgaac gttattaacg tcggtatcgc catgtttagc gatgatctga aaaagcagca
    13261 tgtagaagtg acccaactcg actggacgcc gccggggcag ggcaatatgc aggtggtgca
    13321 ggcactggac aacattgccg attcgccgct ggcggacaaa atcaccgccg ctaaccagca
    13381 ggcgctggag cgcattatcc agtcgcatcc agtgctgatt ggttttgatc aggcgattaa
    13441 cgtggtgccg ggcatgacgg cgaaaaccat tcttcacgcc gggccgccgg tcacctggga
    13501 aaaaatgtgc ggcgcgatga aaggcgcggt caccggagcg ctggtgtttg aaggactggc
    13561 gaaagatctc gacgaggcgg ctgagctggc ggcttccggg gagatcacct tctcgccgtg
    13621 ccacgagcac gactgtgtgg gatcgatggc gggcgtcacc tcggcctcga tgtttatgca
    13681 catcgtgaaa aacaaaacct atggcaacat cgcttatacc aacatgagcg agcagatggc
    13741 gaagattttg cgtatgggcg ctaacgacca gagcgtgatc gaccgcctca actggatgcg
    13801 cgatgtgcag gggccaatgc tgcgtgacgc gatgaaaatt atcggcgaga tcgatctgcg
    13861 cttaatgctg gcgcaggcgc tgcatatggg cgatgaatgc cataaccgca ataacgccgg
    13921 gacgacgctg ctgattcagg cgctgacgcc ggggattatt caggcgggtt attccgttga
    13981 gcaacagcgc gaagtgtttg agtttgtcgc cagcagcgat tacttctccg gcccaacgtg
    14041 gatggcgatg tgtaaagcgg cgatggatgc ggcgcacggc attgaataca gcaccgtggt
    14101 gaccaccatg gcgcgtaacg gcgtcgagtt cggcctgcgg gtcagcggcc tgccggggca
    14161 atggtttacc ggcccggcgc agcaggtcat cggcccgatg tttgccggtt ataagccgga
    14221 agattcgggg ctggatatcg gcgacagcgc catcaccgaa acctacggta tcggcggatt
    14281 tgcgatggcg accgcgcccg cgatcgttgc gctggtgggc ggcacggtgg aagaggctat
    14341 cgatttctcc cgtcagatgc gtgaaatcac ccttggcgaa aaccccaacg tcaccattcc
    14401 gctgctcggt tttatgggcg tgccgtcggc aatcgacatc acccgcgtgg gtagcagcgg
    14461 cattctgccg gtgatcaaca ccgccattgc ccataaagat gcgggcgtcg gcatgattgg
    14521 cgcgggcatt gtgcatccac ccttcgcctg cttcgagaaa gccattcttg gctggtgcga
    14581 acgttacggc gtctgacctg caaagtacgc gttgtctctg ccggatgcgg cgtgaacgcc
    14641 ttatccggcc tacgagtggc acgagaattg taggcctgat aagcgtagcg catcaggcag
    14701 tctggcgttg gtcataaccc catcaccctc tgtcgcggac ataacaacat gaaagaactt
    14761 gtggtcgttg ccattggtgg caacagcatt atcaaagata acgccagcca gtcgattgag
    14821 catcaggcgg aggcggtgaa agccgtggcc gatacggtgc tggaaatgct ggcttccgat
    14881 tacgacattg tgctgaccca cggcaacggg ccgcaggtcg ggctggattt acgccgtgcg
    14941 gagattgccc acgagcgcga agggctgccc ttaacgccgc tggcgaactg tgtggcggat
    15001 acgcaaggtg gcattggcta tctgatccag caggcgctga acaaccgact ggcgcgtcac
    15061 ggcgagaaaa aagccgtcac tgtggtgact caggtggaag tggataaaaa cgatccgggt
    15121 tttgcccatc ccaccaagcc catcggcgca ttctttagtg aaagccagcg tgacgaacta
    15181 caaaaggcaa accctgactg gcgttttgtt gaagatgccg gacggggcta tcgccgcgtg
    15241 gtcgcctcgc cggaaccgaa acgtattgtc gaagcacctg ccattaaggc gctgatccaa
    15301 caaggctttg tggtgattgg cgcgggcggc ggtggaattc ctgtggtgcg caccgaagcg
    15361 ggagattacc aaagcgtgga cgcggttatc gacaaagatc tctccaccgc gctactggcc
    15421 cgcgaaattc acgccgacat tctggtgatc accaccggcg tcgaaaaagt ctgtatccac
    15481 tttggcaagc cgcagcaaca ggcgctcgat cgcgtagata ttgccaccat gacccgctat
    15541 atgcaggaag ggcatttccc acctggcagc atgttgccaa aaatcatcgc cagcctgacg
    15601 ttcctggaac aggacggcaa agaagtgatt atcaccacgc cggaatgcct gcctgcggcg
    15661 ctacgcggcg aaacgggcac ccatattatt aaaacctaag gacgtaagat gaaagaaaac
    15721 aatagccgcc gtgaatttct gagccagagc ggtaagatgg tcaccgccgc cgcgctgttt
    15781 ggtacctcag tgccgctcgc ccatgcgggg gtagctggca ccctaaactg cgaagcgaac
    15841 aacaccatga aaatcactga cccgcattac tatctcgata acgtgctgct ggaaaccggt
    15901 tttgactacg aaaatggcgt ggcggtacag acccgcacgg cgcgccagac cgtggagatt
    15961 caggacggta aaattgttgc cctgcgcgag aacaagcagc atccggacgc cacgctgccg
    16021 cactatgacg ctggcggtaa gctgatgctg cccaccaccc gcgatatgca tattcatctc
    16081 gacaaaacct tctacggcgg gccgtggcgc tcgctcaatc gtccggcagg caccactatc
    16141 caggacatga tcaaactcga gcagaaaatg ctgccggaac tgcaaccgta cacgcaggaa
    16201 cgggcggaaa aactgatcga tttattgcag tcgaaaggca ccactattgc ccgcagccac
    16261 tgcaatatcg aaccggtttc cggcctgaaa aatctgcaaa atttgcaggc ggtgctggcg
    16321 cgacgtcaga cgggcttcga gtgtgagatc gtcgccttcc cgcagcacgg tttgctgctg
    16381 tcgaaatcgg aatccttaat gcgcgaagcg atgcaggcgg gggcgcatta cgtcggcggg
    16441 ctggacccga ccagtgttga tggcgcgatg gaaaaatccc tcgacaccat gttccagatt
    16501 gcgctggact atgacaaagg cgtcgatatt cacctgcacg aaaccacgcc ggcaggcgtg
    16561 gcagccatca attatatggt tgaaacagtg gagaaaacgc cacagctgaa gggcaagctg
    16621 accatcagcc acgcctttgc gctggcaacg ctcaacgaac aacaggtaga tgaactggcg
    16681 caccggatgg cggcgcagcg aatttcgatc gcttcgacgg tgccgattgg cacgctgcat
    16741 atgccgctca aacagctgca cgacaaaggc gtaaaagtga tgaccggcac cgacagcgtt
    16801 atcgaccact ggtcgcctta cggcctgggc gacatgctgg aaaaagccaa tctgtacgcg
    16861 cagctctata ttcgtcctaa cgaacagaac ctctcccgct ctctgttttt agccactggc
    16921 gatgtattgc cgctcaacga aaaaggcgag cgcgtgtggc ccaaagcgca ggatgatgcc
    16981 agttttgtgc tggtggacgc ctcctgttcc gccgaggcgg tggcgcgtat ttcgccgaga
    17041 acggcgacgt tccataaagg gcaactggtg tgggggagtg tggcaggttg atacgaactt
    17101 gatatgtttg caacggtgaa cagtaagaga tttaagcccc agggagtggg gcggcctgag
    17161 tatgagtgtg tcggcagaaa tggacattat ctttgaagaa tatgccctta ttgacgttgt
    17221 gtagataact atttgtctac gtgaaaatat catcagtttt gccgattttt gtcttttacg
    17281 gatagcaaat atcacactta taggcgctcg ccttatgggg aacgttgctg ctctgtttca
    17341 ttcaggctcg cggcatgtta gggctggatc gggtggttta aatattggct atattcaatg
    17401 gacgcgtttt gccgcgatga catatcaggc atcgtcaaat acacatagct aatcaggagt
    17461 aaacacaatg aagatcaaag ctgttggtgc atattccgct aaacaaccgc ttgaaccgat
    17521 ggatatcacc cggcgtgaac cgggaccgca tgatgtcaaa atcgaaatcg cttactgtgg
    17581 cgtctgccat tccgatctcc accaggtccg ttcggagtgg gcggggacgg tttacccctg
    17641 cgtgccgggt catgaaattg tggggcgcgt ggtagccgtt ggtgatcagg tagaaaaaca
    17701 tgcgccgggc gatctggtcg gtgtcggctg cattgtcgac agttgtaaac attgcgaaga
    17761 gtgtgaagac gggctggaaa actactgtga tcacatgacc ggaacctata actcgccgac
    17821 accggatgaa ccgggccata ctctgggagg ctactcacaa cagatcgtcg ttcatgagcg
    17881 atatgttctg cgtattcgtc acccgcaaga gcagctggcg gcggtggctc ctttattgtg
    17941 tgcaggaatc accacgtact cgccgctacg ccactggcag gccgggccgg gtaaaaaagt
    18001 gggcgtggtc ggcatcggcg gtctgggaca tatggggatt aaactggccc acgcgatggg
    18061 ggcgcatgtg gtggcattta ccacttctga gtcaaaacgc gaagcggcaa aagccctggg
    18121 ggccgatgaa gttgttaact cacgcaatgc cgatgagatg gtggctcatg tgaagagttt
    18181 cgatttcatt ttgaatacag tagctgcgcc acataatctc gacgatttta ccaccttgct
    18241 gaagcgcgat ggcaccataa cgctggttgg tgcgcctgcg acaccgcata aatcgccgga
    18301 agttttcaac ctgatcatga aacgccgcgc gatagctggt tctatgattg gcggcattcc
    18361 agaaactcag gagatgctcg atttttgcgc cgaacatggc atcgtggctg atatagagat
    18421 gattcgggcc gatcaaatta atgaagccta tgagcgaatg ctgcgtggtg atgtgaaata
    18481 tcgttttgtt atcgataatc gcacactaac agactgaaaa aaattaataa atatcctgtg
    18541 gtttaacata ttaatttcgc tctccttaac tttttagtta aggagagcga aataatatca
    18601 aagtagtggt aaacctatag cgtaaattca gattgttaaa ttaactctac tactttacac
    18661 gttagttatg agcgatttct gatagtgtct ggtttaatca gagctttatt atctgcgacg
    18721 tttattttta tttaagagag ccacctgcaa gttgttattc caccagagag tgaatcgcaa
    18781 agcaggtcat catttcatct gtatatctgt atgccaaatg gcattccccc tcctttttcg
    18841 ccgatatttt gttgtgatcg acgaagtttc gcttaaaaaa gcaccagcag tggtttcgca
    18901 gctatatggt gtataaaaaa tgttctcata cagatgtttt gtgaatgtgt gggttgacat
    18961 tcatatgaaa aaaatcataa ttccatcatg tttgtgtggg ggcttttctg tatcttacgc
    19021 atcgcactca agcctgacag aaaatatgct gtaaggctca tatcaaaaac cgccattagc
    19081 tcatcaggaa gagcagacga caaccaggat tgttgtatgg tacggggttc gaggcctcga
    19141 tggcggtcca acttttcaaa actcttctga atcagatccc cttattatca tccctgcaaa
    19201 gtggaacatt gccattgttt ggctattcag gacgggtcag accaatgaaa aagcccacac
    19261 aggggagagt aggctgaaat gggaagctaa agactcaagt aaacttatcg gaaataagga
    19321 ccacgcatta cgggggctat catcgccgat ggttgggatt cggcaaatca ggttgattac
    19381 gtagagagta aattatctgc tcaccgctgc gtcacccctt cgtaaatcag gcgtagcgcg
    19441 aatacaccaa taattgcacc aataacccga ctggcaacgc gttgcatacg cccataagca
    19501 cgacgcacag cgggcaaaga aaacgcctgg cttagaaaga ctcgccagat aattgatgtg
    19561 agcacaatcc ccgcccaggc cattaatcgt gcccatgttg gtgtttcggc atttaatgtt
    19621 actgagaaaa tactgataaa aaataaaacg gtttgcgggt tagagagatc ggtaattaat
    19681 ccacggcgga aaaagatata ccagggggca ctaatcggtt gttgtagtgt gctcatttgc
    19741 ggtgttgact ggcggcgcat gctgcaccac gcaaaccata agagataagc gccgccgacg
    19801 attctgataa gcgaaaaaat ctcctcacac tgcgtaatta gcgttgcaag accaaacaaa
    19861 cccaacccgg aataaaatgc atcgcccagc gccacgccca gcccggtcaa cacccccgcg
    19921 cgtcgaccgg aagccaggct ggtttgtact accacaaaga gattggctcc cggattaaaa
    19981 aaagtaatca cgaacaatcc tacggtcagg taaacggcgt gcaaaggatc catagtgatt
    20041 tcatccataa ataagtgaag taacttcatc atatttctac caaaaataat cgggtgcgag
    20101 agagatcaca aagtgtctta tttccggtta ctggcgttta tgccctgact gaactaatta
    20161 ttaatcaacc caataatgtg ggtgggtgat agtgtgataa caactctgga gccgtaatat
    20221 gaaaataatc tctaaaatgt tagtcggtgc gttagcgttt gccgttacca atgtctatgc
    20281 cgcagaatta atgaccaaag cggaatttga aaaggttgca tcgcaatatg aaaaaatagg
    20341 tgatatttca accagtaatg aaatgtcgac cgcagatgcg aaagaagatt tgatcaaaaa
    20401 agccgatgaa aaaggggctg atgtgttggt actgacctct ggtcaaactg acaataagat
    20461 ccacggcacg gcaaatattt ataagaagaa gtaattctga atcctatgta aacatccccg
    20521 atgcgttagt ttatcggtga tcatcatcta tcgaaattta tgccggataa agcgttcgcg
    20581 ctgcattcgg cagttcagct tttcagccgc cgccagaacg tcgtccggct gatacctaaa
    20641 taattcgccg ctgctgtttt atcgccatta aatttctcca gtgcctgttg tgctgtcagc
    20701 aagcctggaa tgggagtctt cgccgactcg cgcgccagtt ccggcagtag cagctgcaaa
    20761 aattgcggcg ttaaatccgg cgtcgattcc acacttaaaa acagcgccag tcgttccatc
    20821 atattgcgca gttcacgaat attgcccggc cagtcgtagt gcaataatag aatctgacag
    20881 gtctctaatc cctgacgtaa tgcggcagaa aaagggacag agagtgccgc cagagacatt
    20941 ttcaaaaagc tttccgccag cggcagaata tccgccaccc gctcgcgtag cggcggcagt
    21001 tgtagacgca aaatactcag ccgataaaac aggtcacggc gaaactgccc ttgctgcata
    21061 tcttcttcca gattgcagtg agtggcgcta atgacccgca catccaccgg aacaggctga
    21121 tgcccgccga cgcgggtgac ctctttttct tccagcaccc gcagcagccg agtctgcaac
    21181 ggcagcggca tttcgcctat ctcgtcaaga aacagcgtac caccgtgggc gatttcaaac
    21241 agcccggcgc gtcctccgcg tcgcgagccg gtaaacgccc cttcctcata gccaaacagc
    21301 tccgcttcca gcagcgattc ggcaatcgcc ccgcagttaa cggcaacaaa cggatgtgac
    21361 tttttgccct gtcgcgcatc gtggcgggaa aaatattccc gatgaatcgc ctgggccgcc
    21421 agctctttgc ccgtccccgt ttccccctca atcaacaccg ccgcactgga gcgggcatac
    21481 agcaaaatag tctgccgcac ctgttccatc tgtggtgatt gaccgagcat atcgcccagc
    21541 acgtaacgag tacgcagggc gttgcgggtg gcatcgtgag tgttatggcg taacgacatg
    21601 cgcgtcatat ccagcgcatc gctgaatgcc tggcgcacgg tggcggcgga atagataaaa
    21661 attccggtca ttccggcttc ttctgccaga tcggtaatca gccctgcgcc gaccaccgct
    21721 tcggtgccgt tggctttcaa ctcattgatt tgcccgcggg cgtcttcttc ggtgatgtag
    21781 ctacgttggt cgaggcgcaa attaaaggtc ttttgaaacg ccaccagcgc tggaatggtt
    21841 tcctgatagg tgacaacacc gatagaagag gtgagttttc cggcttttgc cagtgcctgt
    21901 aacacatcgt agccgctcgg tttaatcaaa ataactggca ctgacaggcg acttttaaga
    21961 tatgcgccgt tagagccagc agcgatgatg gcgtcgcacc gttcgttggc cagtttcttg
    22021 cggatgtagg tcaccgcttt ttcaaagcca agctggatag gggtgatatt cgccaggtga
    22081 tcaaactcga ggctgatatc gcgaaacagc tcgaacaggc gcgttacaga taccgtccag
    22141 ataaccggtt tgtcgtcatt cagccgtggt ggatgtgcca tagcgcaccg caaagttaag
    22201 aaaccgaata ttgggtttag tcttgtttca taattgttgc aatgaaacgc ggtgaaacat
    22261 tgcctgaaac gttaactgaa acgcatattt gcggattact tcatgaattt atctttaact
    22321 cattgaaatt aaatgtttaa ttttattaag gcaattgtgg cacacccatt gctttgtctt
    22381 tatcaacgca aataacaagt tgataacaaa ggatgggcta tgtctctaca ctctccaggt
    22441 aaagcgtttc gcgctgcact gactaaagaa aatccattgc agattgttgg cactatcaac
    22501 gctaaccatg cgctgctggc gcagcgtgcc ggatatcagg cgatttatct ctccggcggt
    22561 ggcgtggcgg cagggtcgct ggggctgccc gatctcggta tttctactct tgatgatgtg
    22621 ctgactgaca ttcgccgtat caccgacgtt tgttcgctac cgctgctggt ggatgcggat
    22681 atcggttttg gttcttctgc ttttaacgtg gcgcgcaccg tgaaatcgat gattaaagcc
    22741 ggtgcggcag gattgcatat tgaagatcag gttggtgcga aacgctgcgg tcatcgcccg
    22801 aacaaagcga tcgtctcgaa agaggaaatg gtggatcgga tccgtgcggc ggtggatgcg
    22861 aaaaccgatc ctgattttgt gatcatggcg cgcaccgatg cgctggcggt agaggggctg
    22921 gatgcggcga tcgagcgtgc gcaggcctat gttgaagcgg gtgccgaaat gctgttcccg
    22981 gaggcgatta ccgaactcgc catgtatcgc cagtttgccg atgcggtgca ggtaccgatc
    23041 ctcgccaaca ttaccgaatt tggcgcaaca ccgctgttta ccaccgacga attacgcagc
    23101 gcccatgtcg caatggcgct ctacccgctt tcagcgtttc gcgccatgaa ccgcgccgct
    23161 gaacatgtct acaacatcct gcgtcaggaa ggcacacaga aaagcgtcat cgacaccatg
    23221 cagacccgca acgagctgta cgaaagcatc aactactacc agtacgaaga gaagctcgac
    23281 gacctgtttg cccgtggtca ggtgaaataa aaacgcccgt tggttgtatt cgacaaccga
    23341 tgcctgatgc gccgctgacg cgacttatca ggcctacgag gtgaactgaa ctgtaggtcg
    23401 gataagacgc atagcgtcgc atccgacaac aatctcgacc ctacaaatga taacaatgac
    23461 gaggacaata tgagcgacac aacgatcctg caaaacagta cccatgtcat taaaccgaaa
    23521 aaatcggtgg cactttccgg cgttccggcg ggcaatacgg cgctctgcac cgtgggtaaa
    23581 agcggcaacg acctgcatta ccgtggctac gatattcttg atctggcgga acattgtgaa
    23641 tttgaagaag tggcgcatct gctgatccac ggcaaactgc caacccgtga cgaactcgcc
    23701 gcctacaaaa cgaaactgaa agccctgcgt ggtttaccgg ctaacgtgcg taccgtgctg
    23761 gaagccttac cggcggcgtc acacccgatg gatgttatgc gcaccggcgt ttccgcgctc
    23821 ggctgcacgc tgccagaaaa agaggggcat accgtctctg gcgcacggga tattgccgac
    23881 aaactgctgg cgtcacttag ctcgattctt ctctactggt atcactacag ccacaacggc
    23941 gaacgcattc agccggaaac cgatgacgac tctatcggcg gtcacttcct gcatctgctg
    24001 cacggcgaaa agccgtcgca aagctgggaa aaggcgatgc atatttcgct ggtgctgtac
    24061 gccgaacacg agtttaacgc ttccaccttt accagccggg tgattgcggg cactggctct
    24121 gatatgtatt ccgccattat tggcgcgatt ggcgcactgc gcgggccgaa acacggcgga
    24181 gcgaatgaag tgtcgctgga gatccagcaa cgctacgaaa cgccggacga agccgaagct
    24241 gatatccgta agcgggtgga aaacaaagaa gtggtcattg gttttgggca tccggtttat
    24301 accatcgccg acccgcgcca ccaggtgatc aaacgcgtgg caaagcagct ctcgcaggaa
    24361 ggcggctcgc tgaagatgta caacatcgcc gatcgcctgg aaacagtgat gtgggagagc
    24421 aaaaagatgt tccccaatct cgactggttc tccgctgttt cctacaacat gatgggtgtt
    24481 cccaccgaga tattcacacc actgtttgtt atcgcccgcg tcactggctg ggcggcgcac
    24541 attatcgaac aacgtcagga caacaaaatt atccgtcctt ccgccaatta tgttggaccg
    24601 gaagaccgcc agtttgtcgc gctggataag cgccagtaaa cctctacgaa taacaataag
    24661 gaaacgtacc caatgtcagc tcaaatcaac aacattcgcc cggaatttga tcgtgaaatc
    24721 gttgatatcg tcgattacgt gatgaactac gaaatcagct ccagagtagc ctacgacacc
    24781 gcacattact gcctgctcga cacgctcggc tgtggtctgg aagctctcga atatccggcc
    24841 tgtaaaaaac tgctggggcc aattgtcccc ggcaccgtcg tacccaatgg cgtgcgcgtc
    24901 cccggaactc agtttcagct cgaccccgtc caggcggcat ttaacattgg cgcgatgatc
    24961 cgttggctcg atttcaacga tacctggctg gcggcggagt gggggcatcc ttccgacaac
    25021 ctcggcggca ttctggcaac ggcggactgg ctttcgcgca acgcggtcgc cagcggcaaa
    25081 gcgccgttga ccatgaaaca ggtgctgacc gcaatgatca aagcccatga aattcagggc
    25141 tgcatcgcgc tggaaaactc ctttaaccgc gtcggcctcg accacgttct gttagtgaaa
    25201 gtggcttcca ccgccgtggt cgccgaaatg ctcggcctga cccgcgagga aattctcaac
    25261 gccgtttcgc tggcatgggt agacggacag tcgctgcgca cctatcgcca tgcgccgaac
    25321 accggtacgc gtaaatcctg ggcggcgggc gatgccactt cccgcgcggt acgtctggca
    25381 ctgatggcga aaaccggcga aatgggttat ccgtcagccc tgactgcgcc ggtgtggggc
    25441 ttctacgacg tctcctttaa aggcgaatcg ttccgcttcc agcgcccgta tggttcttac
    25501 gtgatggaaa atgtgctgtt caaaatctcc ttcccggcgg agttccactc ccagacggca
    25561 gttgaagcag cgatgacgct ctatgaacag atgcaggcag caggcaaaac ggcggcggat
    25621 atcgaaaaag tgaccattcg cacccacgaa gcctgtattc gcatcatcga caaaaaaggg
    25681 ccgctcaata acccggctga ccgcgaccac tgcattcagt acatggtggc gatcccgctg
    25741 ctgttcgggc gcttaacggc ggcagattac gaggacaacg ttgcgcaaga taaacgcatc
    25801 gacgctctgc gcgagaagat caattgcttt gaagatccgg tgtttaccgc tgactaccac
    25861 gacccggaaa aacgcgccat cgccaatgcc ataacccttg agttcaccga cggcacgcga
    25921 tttgaagaag tggtggtgga gtacccaatt ggtcatgctc gccgccgtca ggatggcatt
    25981 ccgaagctgg tcgataaatt caaaatcaat ctcgcgcgcc agttcccgac tcgccagcag
    26041 cagcgcattc tggaggtttc tctcgacaga actcgcctgg aacagatgcc ggtcaatgag
    26101 tatctcgacc tgtacgtcat ttaagtaaac ggcggtaagg cgtaagttca acaggagagc
    26161 attatgtctt ttagcgaatt ttatcagcgt tcgattaacg aaccggagca gttctgggcc
    26221 gagcaggccc ggcgtattga ctggcagacg ccctttacgc aaacgctcga ccacagcaac
    26281 ccgccgtttg cccgttggtt ttgtgaaggc cgaaccaact tgtgtcacaa cgctatcgac
    26341 cgctggctgg agaaacagcc agaggcgctg gcattgattg ccgtctcttc ggaaacagag
    26401 gaagagcgta cctttacctt ccgccaactg catgacgaag tgaatgcggt ggcgtcaatg
    26461 ctgcgctcgc tgggcgtgca gcgtggcgat cgggtgctgg tgtatatgcc gatgattgcc
    26521 gaagcgcata ttaccctgct ggcctgcgcg cgcattggtg ctattcactc ggtggtgttt
    26581 gggggttttg cctcgcacag cgtggcggcg cgaattgatg acgctaaacc ggtgctgatt
    26641 gtctcggctg atgccggggc gcgcggcggt aaaatcattc cgtataaaaa attgctcgac
    26701 gatgcgataa gtcaggcaca gcatcagccg cgtcacgttt tactggtgga tcgcgggctg
    26761 gcgaaaatgg cgcgcgttag cgggcgggat gtcgatttcg cgtcgttgcg ccatcagcac
    26821 atcggcgcgc gggtgccggt ggcatggctg gaatccaacg aaacctcctg cattctctac
    26881 acctccggca cgaccggcaa acctaaaggt gtgcagcgtg atgtcggcgg atatgcggtg
    26941 gcgctggcga cctcgatgga caccattttt ggcggcaaag cgggcggcgt gttcttttgt
    27001 gcttcggata tcggctgggt ggtagggcat tcgtatatcg tttacgcgcc gctgctggcg
    27061 gggatggcga ctatcgttta cgaaggattg ccgacctggc cggactgcgg cgtgtggtgg
    27121 aaaattgtcg agaaatatca ggttagccgc atgttctcag cgccgaccgc cattcgcgtg
    27181 ctgaaaaaat tccctaccgc tgaaattcgc aaacacgatc tttcgtcgct ggaagtgctc
    27241 tatctggctg gagaaccgct ggacgagccg accgccagtt gggtgagcaa tacgctggat
    27301 gtgccggtca tcgacaacta ctggcagacc gaatccggct ggccgattat ggcgattgct
    27361 cgcggtctgg atgacagacc gacgcgtctg ggaagccccg gcgtgccgat gtatggctat
    27421 aacgtgcagt tgctcaatga agtcaccggc gaaccgtgtg gcgtcaatga gaaagggatg
    27481 ctggtagtgg aggggccatt gccgccaggc tgtattcaga ccatctgggg cgacgacgac
    27541 cgctttgtga agacgtactg gtcgctgttt tcccgtccgg tgtacgccac ttttgactgg
    27601 ggcatccgcg atgctgacgg ttatcacttt attctcgggc gcactgacga tgtgattaac
    27661 gttgccggac atcggctggg tacgcgtgag attgaagaga gtatctccag tcatccgggc
    27721 gttgccgaag tggcggtggt tggggtgaaa gatgcgctga aagggcaggt ggcggtggcg
    27781 tttgtcattc cgaaagagag cgacagtctg gaagaccgtg aggtggcgca ctcgcaagag
    27841 aaggcgatta tggcgctggt ggacagccag attggcaact ttggccgccc ggcgcacgtc
    27901 tggtttgtct cgcaattgcc aaaaacgcga tccggaaaaa tgctgcgccg cacgatccag
    27961 gcgatttgcg aaggacgcga tcctggggat ctgacgacca ttgatgatcc ggcgtcgttg
    28021 gatcagatcc gccaggcgat ggaagagtag gtcggataag gcgctcgcgc cgcatccgac
    28081 accgtgcgca gatgcctgat gcgacgctga cgcgtcttat catgcctaca ggcctgaacc
    28141 gtaggtcgga taaggcgctc gcgccgcatc cgacaccatg cgcagatgcc tgatgcgacg
    28201 ctgacgcgtc ttatcatgcc tacccactgt ttttacacag ataagtttcc cccgcctttt
    28261 tgtactcatt catataagaa atatatcccc atacgaaaac gattgctttt tatcttcaga
    28321 tgaatagaat gcggcggatt ttttgggttt caaacagcaa aaagggggaa tttcgtgtcg
    28381 caagataaca actttagcca ggggccagtc ccgcagtcgg cgcggaaagg ggtattggca
    28441 ttgacgttcg tcatgctggg attaaccttc ttttccgcca gtatgtggac cggcggcact
    28501 ctcggaaccg gtcttagcta tcatgatttc ttcctcgcag ttctcatcgg taatcttctc
    28561 ctcggtattt acacttcatt tcttggttac attggcgcaa aaaccggcct gaccacccat
    28621 cttcttgctc gcttctcgtt tggtgttaaa ggctcatggt tgccttcact gctgctgggc
    28681 ggcacccagg ttggctggtt tggcgttggc gtggcgatgt ttgctattcc ggtgggcaag
    28741 gcaaccgggc tggatattaa tttgctgatt gccgtctccg gtttactgat gaccgtcacc
    28801 gtcttctttg gcatttcggc gctgacagtt ctttcggtga ttgcggttcc ggctatcgcc
    28861 tgtcttggcg gttattccgt gtggctggcc gttaacggca tgggcggcct ggacgcatta
    28921 aaagcggtcg ttcccgcaca accgttagat ttcaatgtcg cgctggcgct ggttgtgggg
    28981 tcatttatca gtgcgggcac gctcaccgct gactttgtcc ggtttggtcg taatgccaaa
    29041 ctggcggtgc tggtggcgat ggtggccttt ttcctcggca actcgttgat gtttattttc
    29101 ggtgcagcgg gcgcggcggc actggggatg gcggatatct ctgatgtgat gattgctcag
    29161 ggcctgctgc tgcctgcgat tgtggtgctg gggctgaata tctggaccac caacgataac
    29221 gcgctctatg cgtcgggttt aggtttcgcc aacattaccg gtatgtcgag caaaaccctt
    29281 tcggtgatta acggtattat cggtacggtc tgcgcattat ggctgtataa caattttgtc
    29341 ggctggttga ccttcctttc ggcagctatt cctccggtgg gcggcgtgat catcgctgat
    29401 tatctgatga accgtcgccg ctatgagcac tttgcgacca cgcgtatgat gagtgtcaat
    29461 tgggtggcga ttctggctgt cgcgctgggg attgccgcag gccactggtt accgggaatt
    29521 gttccggtca acgcggtatt aggtggcgcg ctgagctatc tgatccttaa cccgattttg
    29581 aatcgtaaaa cgacagcagc aatgacgcat gtggaggcta acagtgtcga ataatgcttt
    29641 acaaacaatt attaacgccc ggttacccgg caaagagggg ctgtggcaga ttcattttca
    29701 cgacggaaaa atcagcgcca ttgatgcgca atccggcgtg atgcccgtaa ctgaaaacag
    29761 cctggatgcc gaacaaggtt tagttttacc gccgtttgtg gagccgcata ttcacctgga
    29821 caccacgcaa accgccggac aaccgaactg gaatcagtcc ggcacgctgt ttgaaggcat
    29881 tgaacgctgg gccgagcgca aagcgttatt aactcatgac gatgtgaaac aacgcgcatg
    29941 gcaaacgctg aaatggcaga ttgccaacgg cattcagcat gtgcgtaccc atgtcgatgt
    30001 ttcggacgca acgctgactg cgctgaaagc aatgctggaa gtgaaacagg aagttgcgcc
    30061 gtggattgat ctacaaatcg tcgccttccc gcaggaaggg attttgtcgt atcccaatgg
    30121 tgaagcgttg ctggaagagg cgttacgctt aggggcagac gttgttgggg cgattccgca
    30181 ttttgaattt acccgtgaat atggcgtgga gtcgctgcat aaaaccttcg ccctggcgca
    30241 aaaatacgac cgtctcatcg atgttcactg tgacgagatt gatgatgagc aatcacgctt
    30301 tgtcgaaacc gttgctgccc tggcgcaccg tgaaggcatg ggcgcgcgag tcaccgccag
    30361 ccatactacg gcaatgcact cctataacgg ggcgtatact tcgcgcctgt ttcgtttgct
    30421 gaaaatgtcc ggtattaact ttgtcgccaa cccgttggtc aatattcatc tgcaaggacg
    30481 tttcgatacg tatccaaaac gtcgcggcat cacgcgcgtt aaagagatgc tggagtccgg
    30541 cattaacgtc tgctttggtc acgatgatgt cttcgatccg tggtatccgc tgggaacggc
    30601 gaatatgctg caagtgctgc atatggggct gcatgtttgc cagctgatgg gctatgggca
    30661 gattaacgac ggcctgaatt taatcaccca ccacagtgcc agaacgttga atttgcagga
    30721 ttacggcatt gccgccggaa acagcgccaa cctgattatc ctgccggctg aaaatgggtt
    30781 tgacgcgctg cgccgtcagg ttccggtgcg ctattcggta cgtggcggca aggtgattgc
    30841 cagcacaaaa ccggcacaaa ccaccgtata tctggagcag ccagaagcca tcgattacaa
    30901 acggtaatcg gctgggttac cgcgagcgta gtttatgccg gatgcggcgt gaacacctta
    30961 tccggcctac gtagatcact gaaattgtag gcctgataag cggagcgcat caggcaattt
    31021 tgcttattta aactgaagac tcaactttaa aatctttgaa ataatattgc ttatcccggt
    31081 cgtttatttc gcgaataacc cgacaaggaa cgcctgcagc cacgacgttt ggtggaatgt
    31141 cttttgtgac gacactaccc gcgccaataa cagaattatc cccgatggtg atgcctggat
    31201 taataaccac atgacatccg atccagacgt tattgccaat cgttatcgga aaagagtaca
    31261 tctctccgtt ttttctcaat tcatggtgta ccgggtgtcc cgtaacggaa agagtaacgt
    31321 tgggtgcaat cagtacgtta tcaccgatcg ttaccgtgta gtcgtcgaca atggttaaat
    31381 tgaaatttgc ataaaaattg cggcctatat ggatgttgga accgtaagag aaatagacgg
    31441 gggggtctac ccaggcgttt tcccctaccg tggcaaacat ttctttaatc agactttccc
    31501 ttttttcaaa ttctgatgga tgcgagtgat taaactcata cattaacgtt tttccacgaa
    31561 gtcttttttc aggtaagcct tcgcacatat cggtaaatag cttgcctgct tttattcttt
    31621 ctgtcatcga catgttcatt gcgatcattc cgccctgata tgttggtcgg ataaggcgct
    31681 cgcgccgcat ccgacattga ttgcttaagc gacttcattc acctgacgac gcagtagaga
    31741 aagcgggccg gggccgctaa gcgtgaacac ggaaattaag gtgaagccca gcgccaccag
    31801 acccagcacc agataagcgc cctggaaacc gatgctttca tacatattgc ccgccagtac
    31861 agacataaaa atcatcgcca gttgcttaaa gaagcagaaa cagaccagat aaatcgtcgc
    31921 tgaaaaacgc acttcaaact ggctggtaat atatttaaag cagcccacca gcaggaacgg
    31981 tacttcaaac atatgcagcg ttttcagaat aaccacttcc agcgctgagg tggcgaacga
    32041 tgagccaata atacgtacag acataatagt gccagccacc agcagggcat ttttcccacc
    32101 gatgcgatta atgatcagtg gcgcaaagaa cataatcgag gcattaagta attcgcccat
    32161 tgtcgttacg tagccaaata cccgcgtacc ctgttcaccg gtagcaaaaa acgaagtaaa
    32221 gaaattagca aactgttggt caaaaacatc gtaggtgcag gaaacgccaa taacatacag
    32281 tgacaaaaac cacagttttg gctgtctgaa cagttccagc gccagcttaa ggctaaatgc
    32341 cgaatggttg gcacctaccg cattggcaac cgtggctgaa gagggcgcat ccgttttggc
    32401 gaaaaagagt aaaacggcga ggatgagtgc acagccagaa cccagccaga aaacaaactg
    32461 attattgatg gtgaacatga tgccgacaat cgaggcacac agcgcccagc caacacagcc
    32521 aaacatccgc gcgcgaccaa attcgaaatg actgcgacgg ctgactttct cgataaatgc
    32581 ctctactgct ggcgcaccgg cgttaaaaca aaagccaaga taaataccac caacaatcga
    32641 tcctactaaa atgttgtatt gtaacagtgg tccgaagata aaaataaaga acggcgcaaa
    32701 catcactaac atgccggtaa taatccacag caggtatttg cgcagcccga gtttgtcaga
    32761 aagcagacca aacagcggtt ggaataatag cgagaacaga gaaatagcgg caaaa
//
LOCUS       DAPOXO010000060        32805 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPOXO010000060 DAPOXO010000000
VERSION     DAPOXO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32805
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.060"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            170..1753
                     /locus_tag="ROH59_003193"
     CDS             170..1753
                     /locus_tag="ROH59_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDX4805639.1"
                     /translation="MEWIADPSIWAGLITLIVIELVLGIDNLVFIAILAEKLPPKQRD
                     RARVTGLLLAMLMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAVGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEALNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEDEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLRKDGEMEYEV"
     gene            complement(2205..4058)
                     /gene="asmA"
                     /locus_tag="ROH59_003194"
     CDS             complement(2205..4058)
                     /gene="asmA"
                     /locus_tag="ROH59_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HDX4805640.1"
                     /translation="MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRADNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTLSLNGTVDASDYPHDLTA
                     AIEQINWQLQGADLPKQGIQGQGSFQAQWQESHKRLSFNQISLTANDSTLSGQAQVTL
                     TEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGQSQSTLPRPVISSRIDEPAYQ
                     GLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLD
                     ATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQG
                     QAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVT
                     LNDMQGQSPVLALTGEGMLNLADQTCDTQFDIRVVGGWNGESKLIDFLKETPVPLRVY
                     GNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM"
     gene            complement(4080..4661)
                     /gene="dcd"
                     /locus_tag="ROH59_003195"
     CDS             complement(4080..4661)
                     /gene="dcd"
                     /locus_tag="ROH59_003195"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HDX4805641.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            complement(4753..5394)
                     /gene="udk"
                     /locus_tag="ROH59_003196"
     CDS             complement(4753..5394)
                     /gene="udk"
                     /locus_tag="ROH59_003196"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDX4805642.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            5712..9029
                     /locus_tag="ROH59_003197"
     CDS             5712..9029
                     /locus_tag="ROH59_003197"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDX4805643.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKLLPWYNPLQNLADWLRLALGSAIIPPLLGGVLVVLLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQSNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPN
                     IFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIT
                     VKDGIRHIRALANRVLNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANRASFEKQLRILLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGRGRVTIYEPQQVAAHSERAV
                     MSLDEQWRMIKENQLMMIAHGVASPRIPQARNLWLISLKLWSCEGEIIDEQTFRRSFS
                     DPALSHALDRRVFHDFFQQAAKAIASKGLSIALPLSVAGLSSATLVNELIELLENSPL
                     SPRLLHLIIPADAILDHAESVQKLRLAGCRIVFSQVGRDLQIFNSLKANMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            complement(9136..9984)
                     /gene="alkA"
                     /locus_tag="ROH59_003198"
     CDS             complement(9136..9984)
                     /gene="alkA"
                     /locus_tag="ROH59_003198"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HDX4805644.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVSGVETVADSYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSVGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAGR
                     PGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTSRVAQLYGERLDDFPDYVCFPTPQR
                     LAVADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDEA"
     gene            10118..11470
                     /gene="yegD"
                     /locus_tag="ROH59_003199"
     CDS             10118..11470
                     /gene="yegD"
                     /locus_tag="ROH59_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX4805645.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPHLLKMENDSTLLPSMLCAPTRE
                     AVSEWLYRHHDVPADDDETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPEAITQAVIGRPINF
                     QGLGGDEANTQAQGILERAAKRAGFKDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNDLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEESKIALSSVAETRASLPFISDELATLISQQGLESALNQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALTEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            complement(11483..13423)
                     /gene="yegI"
                     /locus_tag="ROH59_003200"
     CDS             complement(11483..13423)
                     /gene="yegI"
                     /locus_tag="ROH59_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310906.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
                     /protein_id="HDX4805646.1"
                     /translation="MKPTLYTATGECVTPGRELGKGGEGAVYDIEEFVESVAKIYHTS
                     PPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYS
                     PAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVMIDS
                     DSFQINANGTLHLCEVGVSHFTPPELQTMPSFVGFERTENHDNFGLALLIFHVLFGGR
                     HPYSGVPLISDAGNALETDIAHFRYAYASDNQRRGLKPPPRSIPLSMLPGDVEAMFQQ
                     AFTESGVATGRPTAKAWVAALDLLRQQLKKCTVSAMHVYPGHLADCPWCALDNQGVIY
                     FIDLGEEVITTGGNFVLAKVWAMVMASVAPPALQLPLPDHFQAAGRPLPSGLLRREYI
                     ILIEIALSGLSLLLCGLQTEPRYIILVPVLAAIWIIGSLTSKAYKVEVQRRREAFNRA
                     KMDYDHLVSQIQQLGGLEGFIAKRAMLEKMKDEILGLPEEEKRDLAALHDTARERQKQ
                     KFLEGFFIDVASIPGVGPARKAALRSFGIETAADVTRRSVKQVRGFGDHLTQAVIDWK
                     ASCERRFVFRPNEAVTPADRQAVMAKMAAKRHRLESALTVGATELQRFRLQAPARTMP
                     LMEPLRQAAEKLAQAQADLSRC"
     gene            complement(13420..14181)
                     /gene="pphC"
                     /locus_tag="ROH59_003201"
     CDS             complement(13420..14181)
                     /gene="pphC"
                     /locus_tag="ROH59_003201"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase PphC"
                     /protein_id="HDX4805647.1"
                     /translation="MSWRLVYASAVGTSHISADLPCQDACQIQVAWLNDQQPLLSVFV
                     ADGAGSASQGGEGAMLAVNEAMAYMSQKVQGGELGLNDVLATDIVLTIRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDLGHGLQLPLTPMVGEYANMTHFI
                     TDEDAVSRLDTFTSTERAHKVAAFTDGIQRLALNMLDNSPHMPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWLP"
     gene            complement(14178..14837)
                     /locus_tag="ROH59_003202"
     CDS             complement(14178..14837)
                     /locus_tag="ROH59_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDX4805648.1"
                     /translation="MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGL
                     VTFRDELLADSLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAQGDTPMGSAITK
                     ALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFTIG
                     VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            complement(15055..15111)
                     /locus_tag="ROH59_003203"
     CDS             complement(15055..15111)
                     /locus_tag="ROH59_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDX4805649.1"
                     /translation="MMKLLIIVVLLVISYPAY"
     gene            complement(15383..15439)
                     /locus_tag="ROH59_003204"
     CDS             complement(15383..15439)
                     /locus_tag="ROH59_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDX4805650.1"
                     /translation="MMKWIIIVVLLVISFPAY"
     gene            15718..16965
                     /gene="mdtA"
                     /locus_tag="ROH59_003205"
     CDS             15718..16965
                     /gene="mdtA"
                     /locus_tag="ROH59_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HDX4805651.1"
                     /translation="MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQ
                     QSPAGGRRGMRAGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLMALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKAASREDTKKGARS"
     gene            16965..20087
                     /gene="mdtB"
                     /locus_tag="ROH59_003206"
     CDS             16965..20087
                     /gene="mdtB"
                     /locus_tag="ROH59_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HDX4805652.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSESVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKI
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SRFARHEEEA"
     gene            20088..23165
                     /gene="mdtC"
                     /locus_tag="ROH59_003207"
     CDS             20088..23165
                     /gene="mdtC"
                     /locus_tag="ROH59_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HDX4805653.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG
                     ALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEV
                     EQTLVISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRML
                     VALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRGERSETAQ
                     QIIDRLRKKLAKEPGANLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQEDNGAEMNLIYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRMRFSRKPKQAVTE"
     gene            23166..24581
                     /locus_tag="ROH59_003208"
     CDS             23166..24581
                     /locus_tag="ROH59_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4805654.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLAIAGLVAVGVVALVLYLLHAQNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMASIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            24578..25981
                     /gene="baeS"
                     /locus_tag="ROH59_003209"
     CDS             24578..25981
                     /gene="baeS"
                     /locus_tag="ROH59_003209"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HDX4805655.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIK
                     HGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPVPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
                     RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSED
                     ELGRLAEDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TLASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPIDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFAD
                     SAPGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     LSITVELPLERDLQREV"
     gene            25978..26700
                     /gene="baeR"
                     /locus_tag="ROH59_003210"
     CDS             25978..26700
                     /gene="baeR"
                     /locus_tag="ROH59_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HDX4805656.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            26880..27212
                     /locus_tag="ROH59_003211"
     CDS             26880..27212
                     /locus_tag="ROH59_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HDX4805657.1"
                     /translation="MAGWFELSKSSDNQFRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            27359..28720
                     /gene="yegQ"
                     /locus_tag="ROH59_003212"
     CDS             27359..28720
                     /gene="yegQ"
                     /locus_tag="ROH59_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HDX4805658.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEHMENAKGEAMPVAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(29220..29537)
                     /locus_tag="ROH59_003213"
     CDS             complement(29220..29537)
                     /locus_tag="ROH59_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310918.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805659.1"
                     /translation="MKKIAAISLISIFLMSGCAVHNDETSIGKFGLAYKSNIQRKLDN
                     QYYTEAEASLARGRISGAENIVKNDAAHFCVTQGKKMQIVKLKTEGAGLHGVARLTFK
                     CGE"
     gene            29952..30851
                     /gene="yegS"
                     /locus_tag="ROH59_003214"
     CDS             29952..30851
                     /gene="yegS"
                     /locus_tag="ROH59_003214"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HDX4805660.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRITWEKG
                     DAARFVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     GVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     GLLQLRIFTGDEIIPTLVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            complement(30933..31706)
                     /locus_tag="ROH59_003215"
     CDS             complement(30933..31706)
                     /locus_tag="ROH59_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4805661.1"
                     /translation="MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLE
                     QKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVI
                     LDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
                     IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSVSGAMVTAANKVIAVLDSSKFNR
                     RGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(31812..>32805)
                     /gene="gatD"
                     /locus_tag="ROH59_003216"
     CDS             complement(31812..>32805)
                     /gene="gatD"
                     /locus_tag="ROH59_003216"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDX4805662.1"
                     /translation="SVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE
                     FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFA
                     EYIVVKRNNVFALPADMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLA
                     IQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSREMSAPQIQGVLRELRFNQLIL
                     ETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS
                     PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP"
BASE COUNT         7700 a         8706 c         8495 g         7904 t
ORIGIN      
        1 atttcttaaa taatgtttta ttattagcac ctttaattct gggataatgt gaggttataa
       61 ccctcaaata atatgagata aatagtgctg caacattgca tttttgcccc gatttatcca
      121 tgatcgaatt gtgacatttg tcatacaacg aataggtttt gtacttacta tggaatggat
      181 tgccgatccg tctatctggg ctgggttaat cacgctgatt gtgatcgaac tggtcctcgg
      241 cattgataac ctggtcttta ttgccatcct cgccgaaaaa ctgccgccga agcagcgcga
      301 ccgcgcacgg gttaccgggc tgctgctggc gatgttaatg cgcctgttac tgctggcgtc
      361 aatctcctgg ctggtcaccc tgactcaacc gctgttcagc ttccgctcgt ttacctttag
      421 cgcccgcgat ttaatcatgc tgtttggtgg tttcttcctg ctgttcaaag ccacgatgga
      481 gctgaacgaa cggctggaag ggaaagacag caataacccc acgcaacgca aaggtgcgaa
      541 gttctggggg gtggtgacac aaattgtggt actggacgcc atcttctcac tcgactcggt
      601 gattaccgcc gtcgggatgg tcgaccattt actggtcatg atggccgccg tggttatcgc
      661 tatcagcctg atgttgatgg ccagcaagcc gttaacgcaa tttgttaaca gtcacccgac
      721 catcgttatt ctctgcctaa gcttcctgtt gatgattggc tttagcctgg tggcagaagg
      781 tttcggcttc gtcattccga aaggctacct gtacgctgct attggtttct cggtgatgat
      841 cgaggcgctc aatcagttgg ctatctttaa ccggcgacgt tttctttccg ctaatcagac
      901 gctgcgccag cggactaccg aagcggtaat gcgcctgctt agtgggcaaa aagaagatgc
      961 ggaactggac gccgaaaccg cgtctatgct ggtggatcat ggtaaccagc aaatctttaa
     1021 tccgcaggaa cggcggatga ttgagcgggt acttaatctt aaccagcgta ccgtcagcag
     1081 cattatgacg tcgcgccacg atattgagca tatcgatctc aacgcgccgg aagacgagat
     1141 ccgccagtta ctggagcgaa atcagcatac gcggcttgtc gttactgatg gcgatgacgc
     1201 agaagatttg ctcggtgttg ttcacgttat cgacctgcta caacagtcac tgcgcggcga
     1261 accgctcaac ctgcgggtgt tgattcgcca gccgctggtg ttcccggaaa ccttgccgtt
     1321 gttacctgcc ctggagcagt tccgtaatgc ccgcacacac tttgcttttg tggtggatga
     1381 gtttggctcg gtggaaggga ttgtgacatt aagtgacgtc actgaaacca ttgccggtaa
     1441 cttaccgaac gaagtggaag agatcgacgc ccgccatgat attcagaaga atgcggacgg
     1501 ttcctggacg gcgaatggtc atatgccgct ggaagatctg gtgcaatatg tgccgttgcc
     1561 gctggatgaa aaacgtgaat atcacaccat tgccgggcta ttgatggaat atttgcaacg
     1621 tattccaaaa cctggcgaag aagttcaggt gggggattat ttgcttaaaa cgttgcaggt
     1681 ggaaagccat cgcgtgcaga aggtgcagat tattccgctg cgtaaggatg gcgagatgga
     1741 gtacgaggtg tgatggcatc ggccatttta cccaatgctg cgtaacgcct tataacttca
     1801 gcaatgaagc gttgtctgtg gtacatggac atcacagcgg gggtgtgggt ccggctgtaa
     1861 atcgccgaat cgtttcctgt aggccggggc agcccacatg gatgtgggct gagggcgcgt
     1921 tttacaggga tgttacctcg cgcccgtacc cgatagccga aaggaataag atgagggaac
     1981 cgcgccagcg gcgatttacc gccgggagcc cgggttgcca gggtggtggc gattgagcca
     2041 ccctggcacg ttcaccggct tgagcgttcc atagtagcga ggaacatcaa gtgaacggaa
     2101 cagccttcga tcttacatat tcagaatata atggtgccgc cacgaacgcc tgatgcgacg
     2161 ctttacgcgt cttatcaggc ctacaggaca ggtcacctgg taacctacat cttctccagc
     2221 aacttcttca catctttgcc attgcgggaa tctttattcc gctcggccca gtcgttaaga
     2281 cggcgttttg cttcatcctg tagatgttta cgcagtaact gatccacttg caggctgtaa
     2341 ttaagttgct gccagttgcc ataaacccgc agcggtactg gcgtttcttt gaggaaatca
     2401 atcagtttgc tttccccgtt ccagccaccc acgacccgaa tatcaaactg ggtgtcgcag
     2461 gtttgatctg ccagattcaa catgccttcc cctgtcagcg ccagcacagg cgattgacct
     2521 tgcatgtcgt ttaacgtcac gacgccatcc ttcaacgtca aatcggtggt aaagcggtca
     2581 agacgcgtca cgttatcgaa gttttcagcg gccttcacat caccaccatt acgttctacc
     2641 gcttgctgaa tcatctgctg gaagttcatc ccttccatgc gtgtatcagt catttcgaca
     2701 tgtgcctgtc cttgccagtt gtggcggaat gcgtcggcat ctatgtcagc accggagaaa
     2761 tcaccagcca gtgacatctt tccggtcaac gaaatcggat agttaaacgc cttcagaatg
     2821 gtgccaatct caacgttttc cagccgtggc tggaagttta tccgcggatt tattgatgtc
     2881 gcgtccaacg tgcccggcag tgaaacctgt ccaccgttaa gtttgccctg cagttgagta
     2941 atttccagca aacccgactt gttggtcatt tgcgtggcaa catctgtaaa attcattccg
     3001 cgccagcgca cgttactggc ctgcaacaaa atatcagccg taaagccttg cagtccctga
     3061 taggccggtt catcaatacg cgaagaaatg accgggcgcg gcaacgttga ttggctctgc
     3121 ccttgctgcg cggcaccgtt ctcaccgttc gctgtttcat taagggggat gaggttgtca
     3181 agattcagtt gcgggaattg cagtctcagc tgccattccg gtttctctgt caacgtgacc
     3241 tgtgcttgcc cgctcagcgt actgtcattg gcggtcaaac tgatttggtt aaatgaaagg
     3301 cgtttatgtg actcctgcca ctgggcctgg aaactcccct gcccctgaat accttgtttt
     3361 ggtaaatcgg ccccctgcaa ctgccagtta atttgttcaa tagccgccgt taaatcatgc
     3421 ggataatcag aagcatctac tgtaccgtta agggataatg tgagatcgcg ctgatcgcga
     3481 ttaacccgcc cggaaaactc aaatgagcca cgatgttggg gatcttgttc catttgcagg
     3541 cggatattgc ggattgtcac ctgctcgtca tcttcatgct ggaacaccag aacgctgtcc
     3601 gccaccttaa gactggatat atcaaacgac catccgcgat cgtctgacag atccggcaag
     3661 gtattgtcgc gcggtgcaac cggagcgtct tcactgcgca ccgcttccgt ctgcggcgtc
     3721 agttggatca ctgccccttt tagcatcacc tgcttaacgc tcagttgatg actcagtagt
     3781 ggtaaaagcg ccacgtccag acgcatgttg tcggcgcgaa ccagtggctg gcttgcgccc
     3841 tgggcggtga gagacattcg cccggagagg atactaagct gcggccagac gtgccaacgc
     3901 agtggcccgt cgagctgcaa ttgataaccg ctacgtgcag caacttgctt gaccatatag
     3961 tcgcggaaat cattcggatt caccagcaac actaacgcag ataacccggc caccagcacg
     4021 accaggagta tcatcagcgt cgtcagaaat cgtctcatgg tatcctcaat gggcctgaat
     4081 tagtctttat cgattcggct ggctaccgcg ccctgctggt tgcgatattt cgcatcttca
     4141 cggcggttgt aaggtcgcgc cgccgggccg gagagcggct caaagctcag cgcaccaatt
     4201 aacatgcccg gacgcagcgc cagcggcagc ttaccggagt tgtaaaactc cagcacaatg
     4261 cagccagacc agcccggatc gatacggtgc gcggtgacgt gcaccatcag ccccagacgc
     4321 gccagtgaag aacgcccgtc cagccagccc accagatcgg ctggcagcgt caccgactcc
     4381 agcgtcaccg ccagcgccag ctctcctggg tgaagataaa acgcctcgcc ctcgtcgagc
     4441 acgatttcat cgctcatcac gcggtcaagc gcggcgctca cttcatcttt gggaccgctc
     4501 agatcgataa acgctgccgt gtgaccacgg aaggtacgaa atttattgcc caggcgcaca
     4561 tccaccgtcg cgccgttaat acgctccact ggcggacgtg ggttgatcga caaacggcct
     4621 tcatcaagcc aggcttcaat atctcggtca cacagacgca tggcattttc tcctttcgag
     4681 catcactccc ttaacgccaa ttacgtcaag ggcataccag gttatcactg aacggtacac
     4741 aatttatcaa gcttattcaa agaactgact tattttcgct ttcaatatat cgatcgcgat
     4801 gcggtttttc ccgccgcgcg gcacgataat gtccgcatat tgtttagaag gctcaatgaa
     4861 ttgcaggaac atcgggcgca cggttttttg atattgcgcc atcactgaat ccattgaacg
     4921 cccacgctcg ttaacgtcac gcttgatgcg gcgcatcaga cagatatcca gcggggtatc
     4981 aacgaaaatg gagaagttaa gttcgtcacg taaacgcgca tccgtcagca acaaaatgcc
     5041 ttcgagaatg atgaccttct tcggctcaac cgtcaccgtt tctttcatac gcgtatgttc
     5101 aacatagctg taaaccggca ggtcaattgc cgagccgcgt ttcaacgctt gtaaatgctc
     5161 aagcagcagg ctgtgatcca tcgcgctggg atggtcgtag ttggtcttaa cgcgttcttc
     5221 catcgacaga tggctttgat ctttgtaata gcagtcttcg ggaattacgc cgatgtgttc
     5281 atcaccgact tgctcacgta attcacgata aagggtactg gcaataagac tcttgccgga
     5341 agccgatgcg ccagcgatac cgataatgac gcactgatga gactgatcag tcatatattt
     5401 agcgacctga ttaacctgga tgttaggaag ggggcgacga agcgccaaac gcggcaatta
     5461 tagggatttc atccgcctga taccagtcga atagcgttgc cgcgcgctca gagttaattg
     5521 ttgacgaaga attcccggtg gcaaattacg ttgatcagtt ttatacaagg taaaaaatgt
     5581 tatacgcagt tgcgcaaatt atccgccttt acgtcacttt atgagcaatt cgcatataaa
     5641 atgtaaaact tttgtactag catgaacaca gaaacgaata ctgacgacct ggccttgcgg
     5701 ataaagcggt aatgagcaaa caatcacagc atgtattaat tgccctgccc cacccgctgc
     5761 ttcacctggt cagtttaggt ttagtctcgt ttatcttcac ccttttctca cttgagcttt
     5821 cgcagtttgg cacccaactc gccccactgt ggttcccgac gtccatcatg atggtggcgt
     5881 tttatcgcca tgccgggcgc atgtggccgg gaattgcgct gagctgctcg ctgggaaata
     5941 tcgccgcatc catcctgctt ttttccacca gctcgctgaa catgacctgg acgaccatca
     6001 atattgttga agccgtggtc ggggcagtgc tgctacgtaa attgctgccg tggtataacc
     6061 ccttgcaaaa tctggctgac tggctgcgtc tggcactcgg cagcgccatt attccgcctc
     6121 tgttgggggg tgttctggtt gtcctgctga cgcccggaga cgatcctctc agggcatttt
     6181 tgatatgggt actgtcagaa tccatcggcg ctctggcact ggtgccgctg ggattgttat
     6241 ttaaaccaca ctatctgctg cgccatcgca acccaaggtt gctttttgag tcgctgctca
     6301 cgttagctat cacgctgacg ttaagctggc tttcgatgct gtatctgccg tggcctttta
     6361 ctttcattat tgtgctgttg atgtggagcg ccgtgcgcct gccacgaatg gaagcctttt
     6421 tgatcttcct taccacagtg atgatggtat cgctgatgat ggccgcggat ccctctctgc
     6481 ttgctacgcc gcgtacgtac ctgatgagtc atatgccgtg gctaccgttt ttgctgatcc
     6541 tgctgcccgc caacatcatg accatggtga tgtatgcctt tcgtgcggaa cgcaaacaca
     6601 tttccgaaag cgaaacccgc tttcggaacg cgatggaata ttccgccatc ggcatggcat
     6661 tagtgggcac cgagggacaa tggctgcaat ccaacaaagc gctctgccag tttctcggtt
     6721 acagtcagga agaactgcgc ggactcacct ttcagcaact gacctggccg gaggatctca
     6781 ataaagatct gcaacaggtt gaaaagctga tcagcggtga aataaacacc tattcaatgg
     6841 aaaaacgcta ctacaaccgc aatggcgatg ttgtctgggc gttgcttgcc gtctcactgg
     6901 tgcgccacac ggatggcacg ccgctctatt ttatcgctca gattgaagac attaacgagc
     6961 taaaacgcac cgaacaggtg aaccagcaac tgatggagcg catcacgctg gctaacgaag
     7021 cgggcgggat tggcatctgg gagtgggagc taaagccgaa tatttttagc tgggataagc
     7081 ggatgttcga gctgtatgaa attcctccgc atatcaaacc gaactggcag gtgtggtacg
     7141 agtgcgtgct gccggaagat cgccagcacg ccgaaaaagt gattcgcgat tcattgcaat
     7201 cacgctctcc ctttaaactg gaatttcgca ttaccgtgaa agacggcatt cgccatatcc
     7261 gcgccctcgc taaccgggta ctgaataaag aaggcgaagt cgaacgcctg ctcggcatta
     7321 atatggatat gaccgaggtt aaacagctta acgaggcatt gtttcaggaa aaagagcgcc
     7381 tgcacattac gctggattcc atcggtgaag ccgtggtctg tattgatatg gcgatgaaaa
     7441 ttacctttat gaatccggtg gcggagaaga tgagcggctg gacgcaggaa gaagcgttag
     7501 gtgttccgct cctgacggtg ttgcatatta cttttggcga caacggacca ttaatggaga
     7561 acatttacag tgccgacacc tcacgttccg cgattgaaca agatgtggtg ttgcactgcc
     7621 gaagcggcgg cagctacgac gtgcattaca gtattacgcc gttaagtact ctggacggca
     7681 gcaatattgg ttcggttctg gtgattcagg acgtcaccga atcgcgcaaa atgctgcgcc
     7741 agctgagcta cagcgcctcc catgatgcac tgacgcatct cgccaatcga gccagttttg
     7801 agaagcaact acgcatcctg ctgcaaacgg taaacagtac acatcagcga catgcactgg
     7861 tgtttatcga tcttgatcgc tttaaagcgg tgaatgacag cgccgggcac gccgctggcg
     7921 acgctttact gcgcgaactg gcgtcattga tgctgagtat gctgcgctcc agcgacgtgc
     7981 tggcgcgact cggtggcgat gaatttggtc tgctgctgcc agattgtaat gtcgaaagtg
     8041 cgcgttttat cgctacacgc attatcagcg ccgtgaatga ctatcacttt atctgggaag
     8101 gacgtgtaca tcgggtaggt gccagtgcag ggattacctt gattgatgac aacaatcatc
     8161 aggcggctga agtgatgtcg caggctgata tcgcctgtta tgcctccaaa aatggtggcc
     8221 ggggccgggt gacgatttac gaaccgcagc aagttgccgc acatagcgaa cgggctgtga
     8281 tgtcgcttga tgaacagtgg cggatgatta aagagaatca gttgatgatg atcgcccacg
     8341 gtgtcgcttc gccgcggatc ccgcaagcgc gtaatttgtg gctgatttca cttaagctct
     8401 ggagttgcga aggcgagatt attgatgaac aaacatttcg tcgtagcttc agcgatccgg
     8461 cacttagcca tgctcttgac cgacgggtat tccacgattt tttccagcag gccgcaaaag
     8521 cgattgccag taaaggctta agcatcgccc tccccctttc cgttgccggt ttgagtagcg
     8581 ccacgctggt gaatgaacta attgagctgc tggaaaatag ccctctatca ccacggttat
     8641 tacatctgat tattccggca gacgcgattt tagatcacgc agaaagcgtg caaaaactgc
     8701 ggctggcggg atgtcggatc gtattcagtc aggtgggccg cgatctgcaa atcttcaact
     8761 cgctgaaagc gaatatggca gattacctgc tacttgatgg tgagttatgc gccaacgtgc
     8821 agggaaattt gatggatgag atgctgatta cgatcattca ggggcacgct cagcggctcg
     8881 ggatgaagac catcgccggg ccagtcgttt tacccttagt gatggatacg ctttctggca
     8941 tcggcgtcga tctgatttat ggcgatgtga ttgccgatgc ccaaccgctg gatttgctgg
     9001 tgaatagcag ttatttcgcg attaactaag ggagcgtttg cccattgcct gatgcgacgc
     9061 taacgcgtct tatcaggcct acaaatcgct cattccccag gccggataag ctcgcaccgc
     9121 atccggcaac caacgtcatg cttcgtctgg ttgccagcct tccgtatacc agatatgcaa
     9181 caacgcataa gaacgccagg gcttccagcg ttcggcataa cggcggattt gtgccggtgt
     9241 cattcccgga aatcgctgtt taatcagata atcatccggc agaaaaacat ctttcgcctg
     9301 ccagccacgc aaagcaaaat aatttgccgt ccagcgcccg atacccggaa aggtttgcag
     9361 cgttttcatc gcttgttcta cgtcgcccgg tattgtcatt ggtaaggtgc cctccagcgc
     9421 cgcatttgcc agatgaatca gcgcctctgc ccgtttcaac ggcataccta acgcttttaa
     9481 tgcctgcggg tcggctactg ccagccgctg aggcgtgggg aagcagacat aatccggaaa
     9541 atcatccagc cgttcgccat aaagctgtgc cactctggag gtcaattttg ccgccatcgc
     9601 cacgctcacc agttggccta aaatcgcccg cacgccctgc tcaaaagcgt caacacaacc
     9661 aggtaaacgc aatccgggcc gccccgcgcc taactttccc aacgcaccgt taacaatctg
     9721 cgggttacat tgcagatcaa acaggcggct cattttcgcc agacactcag cggcaacagg
     9781 ttctaaacct acacttaaat ttatgtgcag agtatggcgg gctatatccg gaatagcagt
     9841 caccacgccg cgatattcgc ctaccgccag actacgggca taataactgt ccgcgaccgt
     9901 ttccacgccg ctcaccgcac gggcggcgag aaatcccaac atccacgacc agtcatacgg
     9961 cggctgccag ttcagggtat acatcgcatc tccttgttaa tccgctttca gcataaacgt
    10021 tattcagacg ttacgctttg ctttcatatt ccggttgtcg cgacggcaac atttcgctaa
    10081 agtcacgccc cttcttcacc ggcatgggga ttatttcgtg tttattggtt ttgattacgg
    10141 tacagcaaac tgttcagtgg cggtcatgcg cgacggtaaa ccgcatttgc taaaaatgga
    10201 aaacgacagc acgctgctgc cttcaatgct ttgcgcgcca acgcgtgaag cggtaagcga
    10261 atggctgtac cgccatcatg atgttccggc agacgacgat gaaacgcagg cgctgttgcg
    10321 tcgggcgatt cgttataacc gcgaagaaga tatcgatgtc acggcgaaaa gcgtgcagtt
    10381 cggtctttct tcactggcac aatacattga tgatccggaa gaagtgtggt ttgtgaaatc
    10441 accaaaatcg ttcctcggtg ccagcggctt aaaaccgcag caggtagcgc tgtttgagga
    10501 tctggtctgc gcaatgatgt tgcacattcg ccaacaggcg caggcgcagc tgccggaggc
    10561 aattactcag gcggtgattg gtcgcccgat caacttccag gggctgggcg gtgatgaagc
    10621 aaacacccag gcgcaaggga ttctggaacg cgcggcgaag cgtgccgggt ttaaggatgt
    10681 ggtattccag tacgagccgg tcgcggctgg gctggattac gaagccacct tgcaggaaga
    10741 aaaacgagtg ctggtagtgg atatcggcgg tggtacgact gactgttcat tgctgctgat
    10801 ggggccgcaa tggcgttcgc gtctcgatcg tgaagccagc ctcctgggtc atagtggttg
    10861 ccgtattggt ggtaacgatc tggatatcgc actggcgttt aagaacctga tgccgttact
    10921 gggcatgggg ggcgaaaccg aaaaaggcat cgccctgccg attctgccgt ggtggaatgc
    10981 ggttgccatc aacgacgtac ctgcgcaaag tgatttctac agtagtgcca acggtcgtct
    11041 gcttaacgat ctggtacgcg atgcccgcga accggaaaaa gtggccctgt tacagaaagt
    11101 ctggcgtcag cgtttaagct atcgcctggt acgtagcgca gaagagagca aaattgcgct
    11161 ttcaagcgta gcggaaaccc gcgcctcact gccgtttatc agcgatgaac tggctacgct
    11221 gattagccag caagggctgg aaagcgccct caaccagcca ctggcgcgga ttctggaaca
    11281 ggtgcaactg gcgctggata acgcccagga aaaaccggat gttatctatc tgaccggcgg
    11341 tagcgcccgt tcaccgctga ttaaaaaagc gctgacagaa cagttgccgg gcattccgat
    11401 tgcaggtggc gatgactttg gctccgtcac cgccgggctg gcacgctggg cggaagtggt
    11461 gtttcgttaa ttgaaaactg gctcagcaac ggcttaaatc agcctgcgcc tgagccagtt
    11521 tttctgccgc ctgacgtaac ggttccatca acggcatggt ccgtgctgga gcttgaaggc
    11581 ggaatcgctg caactctgtc gcaccgacag tcagcgccga ttccagccga tgtcgtttgg
    11641 cggccatttt tgccattacc gcttgtctgt ctgcaggcgt taccgcttcg ttcggcctga
    11701 aaacaaaacg gcgttcgcaa ctcgctttcc agtcgataac cgcctgggtc agatgatcac
    11761 caaaacccct aacttgctta acgctccgtc gggtaacgtc cgctgctgtt tcaataccaa
    11821 aggaccgtaa cgccgcttta cgcgcagggc caacgccggg aatagaggca acatcaataa
    11881 aaaatccctc cagaaacttc tgcttctgcc gttcccttgc ggtgtcgtga agtgctgcca
    11941 gatcgcgctt ttcttcttcc ggtaacccaa gaatttcgtc cttcattttt tcgagcatcg
    12001 cccgtttggc gataaaacct tccagcccgc ccaactgttg gatctggctg actaaatggt
    12061 catagtccat ttttgcgcga ttaaaagcct ctcttcgtcg ctggacttct actttgtacg
    12121 ctttgcttgt caggctgcca ataatccaga tagccgccag cacgggaacc aaaatgatat
    12181 aacgcggttc tgtctgaagg ccgcaaagca gcagcgataa ccctgacagt gcgatctcaa
    12241 tcagaatgat gtattcgcgc cttaacaggc ctgaaggaag cggcctgcca gcagcctgga
    12301 aatgatcggg taatggcaat tgcaatgctg gcggtgctac tgacgccatc accatcgccc
    12361 agactttcgc cagcacaaaa ttcccgccgg tggtaatgac ctcttcgccg agatcaataa
    12421 aatagataac accttgatta tccagcgcac accatgggca gtcagccaaa tgaccgggat
    12481 aaacatgcat tgccgaaacg gtacatttct ttaactgttg gcgtagtaaa tcaagtgccg
    12541 ctacccacgc ttttgccgtc ggacgcccgg ttgccacgcc actttccgtg aatgcctgct
    12601 gaaacatggc ttcaacatcg cccggtaaca tcgacagcgg aatcgatcgt ggcggcggtt
    12661 ttaaaccacg tcgctgatta tctgacgcgt aggcataacg gaaatgggca atatccgtct
    12721 ccagcgcatt acccgcatca gagataagcg gtacaccgga ataaggatgc cgcccaccaa
    12781 acaagacgtg aaatatcagc aacgcaaggc caaaattatc gtgattttct gtgcgttcaa
    12841 agccgacaaa tgatggcatg gtttgcagct ctggcggcgt aaaatgcgac acgccgactt
    12901 cgcataaatg cagtgtacca ttggcattaa tctgaaagga gtcgctatca atcatcacca
    12961 ctttgctgtc gcgacctacc ataaagctgt tctggtttac gtcacccacg acgtgcccgt
    13021 gctcgtgaac cgtagcaaaa gatgaagcaa tattgcgcgc aacatagagt agaaaatccc
    13081 acgcacaatg agggtaactc tggcgacgat gtgccgggct atagatcata tgaatcggtt
    13141 ctttaccaga aacttttggc atcataaaac cgataacttt tccacctcgt ccaccgtgaa
    13201 gcgttgcctg cggccaggcg acataattca acaactgcgc gtcagctgtc gcagccataa
    13261 aggcaagttt gtcctgtttt aaggcgggag gcgacgtgtg ataaatcttg gcgacgctct
    13321 cgacaaactc ctcgatatca taaaccgcac cttcgccgcc tttgcccagt tcacggcctg
    13381 gcgtaacgca ctcaccagta gcagtatata aagtgggttt catggtaacc acagcgccag
    13441 tgccaacgtt ttatcatcat ccgtacgctc gtttaccgcc gggctggaca aaaactgctt
    13501 taacaattca ggtaataaat cgagttgttc ctgcgttgct gacgccagtc cattgaaaaa
    13561 cggggtaaag aaaggcatat gcggagaatt atccagcata tttaacgcca gtcgctgaat
    13621 accatccgta aatgctgcaa ctttgtgcgc acgctcagtg ctggtgaaag tatccagtct
    13681 ggaaacggca tcttcatcag taatgaagtg cgtcatattg gcatattccc ccaccatcgg
    13741 cgtgagcggc agttgcaaac cgtgacccaa atctaccacc acgccgccat cgccaatctg
    13801 cataatcaag gtgccattag ctgatgaaat caatcccaaa aacgtgcagg caaaatcgcg
    13861 aaccgctaat tctttggctt ccgcctcggc aaaaagtcgc tgacgaatgg tcagcacaat
    13921 gtccgttgcg aggacatcat taagccccaa ttccccgccc tgcacttttt gcgacatata
    13981 agccatcgct tcattgacgg cgagcatcgc accttcgcct ccctgcgagg cgctacctgc
    14041 gccatcagcg acaaataccg acaataatgg ctgctggtca tttagccagg caacctgtat
    14101 ctggcaggca tcctggcaag gcaagtccgc actgatgtgc gacgttccaa cggctgatgc
    14161 atagaccagt cgccagctca cactgacgtc cagccttttg gcgcttccag cacaacttcc
    14221 gttcccggcg tggagcggga aaccgaacgc agcgaactgg ataaccagct aaacagttca
    14281 cggaattgta atccctgcag tggcaaaggc tgacgaacgc tgatttgtgc cagcgtcttc
    14341 atatccgccc cctgaacgcc gatggtaaag aaggcaaact tcttatcttc ttccccctga
    14401 aacactttgt tggcggcagc ctgccactca tcggttggtg caccatcggt gatcaggaaa
    14461 atccacggac gataatagga aataccattg gcacgatatt cacgtttccg ctcctcaacc
    14521 atatccaggg ctttggtaat ggcagagccc attggtgtat cgccctgggc aaacaggatg
    14581 ggcgggaaaa aattagcggc gctggtaaag ggttgttcca catgcaccgg gccgaacgtc
    14641 acaatgccga gttccactct ttttaaggcc agcgaatcgg caagcagctc atcgcgaaag
    14701 gtaaccaatc cggcgttaag ttcattaatg ggtctaccgt tcatagaacc agaaacatcc
    14761 agcagcaaaa tgcaggggca acgtggttcc gggttactgg caaaatcgct ggtggcaaac
    14821 gtgatttgtt cgctcataag aaatcctttc ttagagaatt attgaggtcc ggtatcatac
    14881 cgactgcaat aatgaaataa gagcaaacga agaaactttc agaattaggc ccggcggcgc
    14941 agaagatttt gctattcgcc tcgcaagaac gtgggcttac agattgacaa caagggttga
    15001 gtgacataat ttcaggagtg agggtagagc ggggtttccc ccgccctggt agtcttagta
    15061 tgctgggtag ctaatgacta agagcaccac gatgatgagt agcttcatca tgaccctttc
    15121 cttatttaag gccccttcct cgggaggggc tttcccgttt cagcgtcccg ctgaaatctt
    15181 cggcttacct cctttcgccc tgtatgcagt ctatcgctga cttgcggata aaatagtttc
    15241 aagtgtgatt attgcgtaac gactcgcaaa gaatatttgc tggcaggatc gcagactgca
    15301 aagtctgcgg attgacaatt ggaccgtgaa ggcatacttt caggaatgag ggttgagcgg
    15361 ggtttccccc gccctggtag tcttagtaag ccgggaagct tatgactaag agcaccacga
    15421 tgatgatcca cttcatcatg accctttcct tatttatggc cccttcctcg ggaggggctt
    15481 tcccgtttca gcgtcccgct gaaatcgtcg gcttatctcc tttcgccatg caagcagtct
    15541 atcgctaacg cgtagataaa atagtttcat gtgttattac tggatgcgtg ctcgcaaaag
    15601 tgcccgtcat tcagacgatt cccgacagtg tttcataatt cctccatttt tctcccttat
    15661 tggctggcta cactagtatc attccgcgaa acgtttcagg aagagaaact cttaacgatg
    15721 aaaggcagtt ataaatcccg ttgggtaatc gtaatcgtgg tggttatcgc cgccatcgcc
    15781 gcattctggt tctggcaagg ccgcaatgac tcccagagtg cagcccctgg ggcgacgaaa
    15841 caagcgcagc aatcgccagc gggtggtcgc cgtggtatgc gtgccggccc attagctcct
    15901 gttcaggcgg cgaccgcagt agaacaggct gttccacgtt acctcaccgg gcttggcacc
    15961 attaccgccg ctaatactgt tacggtgcgc agccgcgtgg acggtcaact gatggcgtta
    16021 catttccagg aaggccagca ggtcaaagcc ggcgatttac tggcagaaat tgacccaagc
    16081 cagttcaaag ttgcattagc acaagcccag ggccaactgg caaaagataa agccacgctc
    16141 gccaacgccc gccgtgacct ggcgcgttat caacaactgg caaaaaccaa tctcgtatct
    16201 cgtcaggaac tggatgccca acaagcgctg gtcagtgaaa ccgaaggcac cattaaggct
    16261 gatgaagcaa gcgtcgccag cgcgcagttg caactcgact ggagccgtat caccgcacca
    16321 gttgatggtc gcgttggtct caagcaggtt gatgttggta accaaatctc cagtggcgac
    16381 accaccggga ttgtggtgat cacccaaaca catcctatcg atctggtctt tactctgccg
    16441 gaaagcgata tcgccaccgt tgtgcaggcg caaaaagccg gaaaaccgct ggtggtagaa
    16501 gcctgggatc gcaccaactc gaagaaatta agtgaaggca cactgttaag ccttgataac
    16561 caaatcgatg ccactaccgg tacgattaaa gtgaaagcac gctttaataa tcaggatgat
    16621 gcgctgtttc ccaatcagtt tgttaacgca cgcatgttag tcgacaccga acaaaacgcc
    16681 gtggtgatcc caaccgccgc cctgcaaatg ggcaacgaag gccattttgt ctgggtgctg
    16741 aatagcgaaa acaaggtcag caaacatctg gtgacaccag gcattcagga cagtcagaaa
    16801 gtggtgatcc gcgcaggtat ttctgcgggc gaccgcgtag tgacggacgg aattgatcgc
    16861 ctgaccgaag gggcgaaagt ggaagtggtg gaagcccaga gcgccactac tccggaagaa
    16921 aaagccgcca gccgcgaaga cacgaaaaaa ggagcacgct cctgatgcag gtgttacccc
    16981 cgagcagcac aggcggcccg tcgcgcctgt ttattatgcg tcctgtcgcc accacgctgc
    17041 tgatggtggc gatcttactc gccgggatta tcggttatcg cgccctgccc gtttcggcgc
    17101 tgccggaagt ggactatcca accattcagg tggtcacgct ttatccaggt gcaagcccgg
    17161 atgtcatgac ctctgccgtt accgcgccgc tcgaacgcca gttcgggcag atgtctggcc
    17221 tgaaacagat gtcgtcgcaa agttccggcg gtgcgtcagt tatcacttta cagttccagc
    17281 taacattgcc gctggatgtc gccgagcagg aagtgcaggc cgcgattaac gctgcgacca
    17341 acctgctacc gagcgatctg cctaacccgc cggtttacag caaagtgaac ccggcagatc
    17401 caccgatcat gacgctcgct gtcacctcaa ccgccatgcc gatgacgcag gtggaagata
    17461 tggtggaaac ccgcgtcgcg cagaaaatct cgcagatttc cggcgtaggg ctggtgacac
    17521 tttccggcgg gcagcgtccg gcggtacgcg taaaactcaa cgctcaggca attgccgctc
    17581 tcggcctgac cagcgaaagt gtgcgcaccg ccattactgg cgcgaacgtt aactcagcga
    17641 aagggagcct tgacggccct tctcgcgcgg tcacgctgtc agcgaatgac cagatgcaat
    17701 ccgccgaaga gtatcgccag ctaatcatcg cctaccagaa cggcgcacca attcgtcttg
    17761 gcgatgtcgc aaccgtagag caaggagcag aaaacagctg gctcggcgcg tgggcgaaca
    17821 aagaacaggc cattgtgatg aatgttcagc gccagcccgg tgctaacatt atctccaccg
    17881 ccgacagcat ccggcagatg ctaccacagc tcaccgagag tctgccgaaa tcggtgaagg
    17941 tgacggtact ttctgaccgt accaccaata tccgcgcatc ggtcgacgat acccagtttg
    18001 agctgatgat ggctatcgcg ctggtagtca tgattatcta cctgtttttg cgcaatattc
    18061 cggcgaccat cattcccggt gttgctgtac cgctgtcgtt aattggcacc tttgcggtca
    18121 tggtgtttct cgatttttca atcaataacc tgacgttgat ggcgttaact atcgccaccg
    18181 gattcgtggt cgatgacgcc atcgtggtga tcgaaaacat ttcccgctat atcgaaaaag
    18241 gcgaaaaacc gctggcagcc gcgctcaaag gcgcgggtga aatcggcttt accattatct
    18301 cgctgacctt ctcgctgatt gcggtattga tccccctgct gtttatgggc gatatcgtcg
    18361 ggcgactgtt ccgcgaattt gctattaccc tggcagtcgc gattttgatc tcagcagtgg
    18421 tgtcgctgac cctgacaccg atgatgtgcg cgcggatgct cagccaggag tcgctgcgta
    18481 aacagaaccg cttctcccgt gcctcggaga aaatgttcga caggataatc gccgcctatg
    18541 gtcgtggact ggcgaaagtg ctgaatcatc cgtggctgac cttaagcgta gcgctcagca
    18601 cgctgctgct tagcgtgctg ctgtgggtgt tcattccgaa aggtttcttc ccggtacagg
    18661 acaacggcat aattcagggc actttgcagg caccgcaatc cagctccttt gccaatatgg
    18721 cccagcggca acgccaggtc gcggacgtga ttttgcagga tccggcagtg caaagtttga
    18781 cctcatttgt tggcgttgat ggcactaacc cgtcgctgaa cagtgcgcgt ttacagatca
    18841 atctcaaacc actggatgaa cgagatgacc gggtgcaaaa agtcatcgcc cgtctgcaaa
    18901 cggcggtgga taaagtgccg ggcgtagatc tcttcctgca accaacgcag gacctgacta
    18961 ttgatactca ggtcagccgc acccagtacc agtttacctt gcaggccacg tcactggatg
    19021 cgctcagtac ctgggtgcca cagttgatgg aaaaactcca gcagctgcca cagctttctg
    19081 atgtctccag cgactggcag gacaaagggc tggtggcgta tgtcaatgtc gacagggaca
    19141 gcgccagccg tctggggatc agcatggcgg atgtcgataa cgccctgtac aacgcgtttg
    19201 gtcagcgact gatttccact atttatactc aggctaacca gtatcgcgtg gtgctggaac
    19261 acaacaccga aaatacccca ggcctcgcgg cgctggatac cattcgcctg accagcagcg
    19321 acggtggcgt ggtgccgtta agctcaattg ccaaaattga gcagcgtttt gcgccgcttt
    19381 ccatcaacca tctggatcag ttcccggtaa cgactatctc ctttaacgtg ccggataact
    19441 attcgctggg cgatgcggtg caggcgatta tggacacaga gaagacgctg aatctgccgg
    19501 tggatatcac cacgcagttc cagggcagca ccctcgcctt ccagtcggcg ctgggcagca
    19561 ctgtctggct gattgtcgcg gcggtggtgg cgatgtatat cgtgctcggc attctgtacg
    19621 agagctttat tcacccgatc accattctct cgacgctacc caccgcaggg gtcggcgcgc
    19681 tgctggcgtt aatgattgcc ggtagcgaac tggatgtgat tgccattatc ggcattattt
    19741 tgctgatcgg tatcgtgaag aagaacgcca tcatgatgat cgacttcgcg ctggctgctg
    19801 agcgcgagca aggcatgtcg ccgcgcgaag ctatttacca ggcctgtctg ttgcgttttc
    19861 gtccgatcct gatgaccact ctggcggctc tgcttggtgc gctgccgctg atgttgagta
    19921 ccggggtcgg cgcggaactg cgtcgtccgt taggtatcgg catggtcggc ggtctgattg
    19981 tcagccaggt gctgacgctg tttaccacgc cggtgattta tctgttgttc gaccgtctgg
    20041 cattgtggac caaaagccgt tttgcccgtc atgaagagga ggcgtaagtg aagttttttg
    20101 ccctcttcat ttaccgcccg gtggcgacga ttttactgtc ggtcgccatt accctgtgcg
    20161 gcatactggg tttccgtatg ctgccagtcg ccccgctgcc gcaggtcgat tttccggtga
    20221 tcatggtcag cgcctcgctg cccggtgcgt caccagaaac aatggcgtct tccgttgcca
    20281 cgccgctgga gcgctcactt gggcgcattg ccggagtcag cgaaatgacc tccagcagtt
    20341 cgctcggcag cacgcgcatt attttgcagt ttgattttga ccgggatatc aacggcgcag
    20401 cgcgcgatgt gcaggcggcg atcaacgccg cgcaaagtct gctacccagc gggatgccca
    20461 gccgtccgac ctatcgcaaa gcgaacccat cggatgcgcc aattatgatc ctcacgctga
    20521 catccgatac ttattcgcag ggtgaactgt acgatttcgc ctcgacacag ctggctccga
    20581 cgatttcgca aatcgacggt gtcggtgatg tcgatgttgg cggcagctcg ctgcccgccg
    20641 tacgcgtcgg gctgaatccg caggcgctgt ttaatcaggg cgtctcgctg gacgacgtac
    20701 gcaccgccat cagcaatgcc aacgtgcgta aaccgcaggg ggcgctggaa gatggtactc
    20761 accgctggca gatccagact aacgatgaac tgaaaaccgc cgctgaatat cagccgctga
    20821 ttattcatta caacaacggc ggagcggttc gtctgggcga tgtggcgacg gtgaccgact
    20881 cagtacagga tgtgcgcaac gccgggatga ccaacgccaa accggctatt ttgctgatga
    20941 tccgcaagct gccggaagcc aatattatcc agacggtaga cagcatccgc gcccgtctgc
    21001 cggaattaca atccaccatc ccggcagcaa ttgatctgca aattgcccaa gatcgctccc
    21061 ctactatccg cgcgtcgctg gaagaggttg agcagacgct ggtaatctca gttgcactgg
    21121 tgattctggt ggtgtttttg ttcctgcgtt cgggtcgcgc caccattatt cccgccgttg
    21181 cggtgccggt ttcgctgatt ggtacgtttg cggcgatgta cctgtgtggt ttcagtctca
    21241 ataatctttc gttaatggcg ctcactatcg ccactggctt tgtggtggat gacgccatcg
    21301 tggtgctgga aaacattgcc cgtcatctgg aagcggggat gaaaccgcta caggccgcgc
    21361 tacaaggtac tcgcgaagtc ggctttacgg tgctgtcgat gagtctgtca ctggtggcgg
    21421 tgttcctgcc gctgctgttg atgggcggat tgccgggtcg cctgttacgc gagtttgccg
    21481 tgacgctttc tgtcgccatt ggtatttcgc tgctggtttc cctgacgtta acgccgatga
    21541 tgtgcggctg gatgctaaaa gccagcaagc cgcgcgagca aaagcgactg cgtggctttg
    21601 gtcgcatgtt ggtagccctg caacaaggct atggcaagtc gctgaaatgg gtgctcaatc
    21661 atacccgtct ggtgggcgtg gtgctgcttg gcaccattgc gctgaatatc tggctgtata
    21721 tctcgatccc gaaaaccttc ttcccggagc aggacaccgg cgtactgatg ggtgggatac
    21781 aggctgacca gagtatttcg tttcaggcga tgcgcggtaa gttgcaggac ttcatgaaaa
    21841 ttatccgtga cgatccggcg gtggataatg tcaccggctt taccggcggt tcacgggtga
    21901 acagtggaat gatgtttatc acccttaaac cacgcggcga gcggagcgaa acggcccaac
    21961 agattatcga tcgcttgcgt aaaaaactgg ctaaagaacc gggagcgaat ctgttcctga
    22021 tggcggtaca ggatattcgc gttggcggac gtcaggctaa cgccagttac cagtacacgt
    22081 tgttatccga cgacctggcg gcactgcgcg aatgggagcc gaaaatccgc aaaaaactgg
    22141 cgacattgcc agagctggct gatgttaact ccgatcagga agataatggc gcggagatga
    22201 accttattta cgatcgcgac accatggcgc gattgggaat tgacgtgcaa gccgccaaca
    22261 gcctgttaaa taacgccttc ggtcagcggc aaatctcgac catttaccag ccgatgaacc
    22321 agtacaaagt ggtgatggaa gtggatccgc gctataccca ggacatcagt gcactggaaa
    22381 aaatgttcgt tatcaataac gaaggaaaag cgatcccgct gtcgtatttc gctaaatggc
    22441 aaccggcgaa cgctccactg tcggtgaatc atcagggatt atcggcggcc tcgaccattt
    22501 cgttcaacct gccgaccggg aaatcgctct cggacgccag tgcggcgatc gatcgcgcaa
    22561 tgacccagct tggtgtgcct tcgacggtgc gcggcagttt tgccggaaca gcgcaggtgt
    22621 tccaggagac gatgaactca caggtgatcc tgattatcgc cgccatcgcc acggtatata
    22681 tcgtactggg tatcctttac gagagttatg tgcatccact gacgattctc tccaccctac
    22741 cttcggcggg cgtcggagcg ctgttggcgc tggagctgtt caatgccccg ttcagcctaa
    22801 ttgcgctgat agggatcatg ttattaatcg gcatcgtgaa gaaaaacgcc attatgatgg
    22861 tcgattttgc gcttgaagcc caacggcacg gtaacctgac gccgcaggaa gctattttcc
    22921 aggcctgtct gctgcgtttt cgcccgatta tgatgactac cctggcggcg ctgtttggtg
    22981 cgctgccgct ggtattgtcg ggcggtgacg gctcggagtt gcggcaacca ttggggatca
    23041 ccattgtcgg cggtctggtc atgagccagc ttctgacgct gtataccacg ccggtggtgt
    23101 atctcttttt cgaccgtctg cggatgcgtt tttcgcgtaa acctaaacaa gcggtaaccg
    23161 agtaaatgac agatcttccc gacagcaccc gctggcaatt gtggattgtg gctttcggct
    23221 tctttatgca gtcgctggac accaccatcg ttaacaccgc gcttccctca atggcgcaaa
    23281 gcctcgggga aagtccgttg catatgcaca tggtcattgt ctcttatgta ctgaccgtgg
    23341 cggtgatgct gcccgccagc ggctggctgg cggacaaagt cggcgtgcgc aatattttct
    23401 ttaccgccat cgtgctgttt actctcggtt cactgttttg cgcgctttcc ggcacgctga
    23461 acgaactgtt gctggcacgc gcgttacagg gcgttggcgg cgcgatgatg gtgccggtcg
    23521 gcaggttgac ggtgatgaaa atcgtaccgc gcgagcaata tatggcggcg atgacctttg
    23581 tcacgctgcc cggtcaggtc gggccgctgc ttggcccggc gctcggcggt ctgctggtgg
    23641 agtacgcatc gtggcactgg atctttttga tcaacattcc ggtgggaatt attggcgcga
    23701 tcgccacact gatgttaatg ccgaactaca ccatgcagac gcggcgcttt gatctctccg
    23761 gctttctgtt gctggcggtt ggcatggcgg tattaaccct ggcgctggac ggcagtaaag
    23821 gtacaggttt atcgccgctg gcgattgctg gcctggtcgc agttggcgtg gtagcactgg
    23881 tgctttatct gctgcacgcc caaaataaca accgcgccct gttcagtctg aaactgttcc
    23941 gcactcgtac cttttcgctg ggcctggcgg ggagctttgc cggacgtatt ggcagtggca
    24001 tgttgccctt tatgacaccg gttttcctgc aaattggcct cggtttctcg ccgtttcatg
    24061 ccggactgat gatgatcccg atggtactcg gcagcatggg aatgaagcga attgtggtac
    24121 aggtagtgaa tcgctttggt tatcgtcggg tactggtggc gaccacgctg ggcctgtcgc
    24181 tggtcaccct gttgtttatg actaccgctc tgctgggctg gtactacgtt ttgccgttcg
    24241 tcctgttttt acaaggaatg gtcaactcga cacgtttctc ctccatgaac accctgacgc
    24301 tgaaagatct cccggacaac ctggcgagca gcggcaacag tctgctgtcg atgattatgc
    24361 aattgtcgat gagtattggc gtcaccatcg ccgggctgtt gctgggactt tttggttcgc
    24421 agcatgtcag cgtcgacagc ggcaccacac aaaccgtctt tatgtacacc tggcttagca
    24481 tggcgtctat catcgccctt ccggcgttca tctttgccag agtgccgaac gatacgcatc
    24541 aaaatgtggc tatttcacgg cgaaaaagga gcgcgcaatg aagttctggc gacccggtat
    24601 taccggcaaa ctgtttctgg cgattttcgc cacctgcatt gtcttattga tcacgatgca
    24661 ctgggcggta cgtatcagtt ttgagcgcgg ctttatcgat tacatcaagc atggtaatga
    24721 acaacggctg caaatgctcg gcgatgcgct tggtgagcag tacgcccagc acgggaactg
    24781 gcgcttcctg cgtaataacg atcgctttgt atttcagatc ctacgttcac tggagcatga
    24841 taacaacgaa gataagcccg gccccggtat gccgccacac ggctggcgca cacaattttg
    24901 ggtggttgat caaaacaaca aagtgctggt tggcccgcga gcaccagttc cacccgacgg
    24961 cacacggcgg cccattatgg tcaatggtgc ggaagttggc gcggtgatcg cctcccctgt
    25021 tgaacgactg acccgtaata ctgatatcaa ttttgacaga caacagcggc aaaccagttg
    25081 gctgattgtg gctttatcta ccttattagc ggcgctggcg acattcccac tggcgcgcgg
    25141 tttgctggct ccggtaaaac gactggtgga tggcacgcac aaactggcag cgggtgattt
    25201 cactactcgc gtagccccca ccagcgaaga tgagttgggc agactggcag aggatttcaa
    25261 tcaactcgcc agcacactgg agaaaaacca gcagatgcgc cgcgatttta tggccgatat
    25321 ttctcatgaa ctgcgcacgc ctttagcagt actgcgcggc gaactggaag ccattcagga
    25381 tggtgtgcgt aaattcacgc cggagacgct ggcttcttta caggcagaag taggtacact
    25441 gacaaaactg gttgacgatc tccatcaatt gtctatgtct gatgaaggcg ctctcgccta
    25501 tcaaaaagca ccgatagatt tgatcccact gctggaagtg gcgggaggcg catttcgcga
    25561 acgattcgcc agccgtggcc tgaaattgca attttccctg ccagacagta ttaccgtatt
    25621 tggcgatcgc gatcgtttaa tgcagttgtt caataactta ctggaaaaca gcctgcgcta
    25681 cactgacagc ggcggcagcc tgaaaatctc tgccgagcag cacgacaaaa cggtgcgcct
    25741 gacctttgcc gacagtgcgc cgggtgtcag tgacgatcag ctacaaaaat tgtttgaacg
    25801 tttttatcgc accgaaggtt cccgcaaccg cgccagcggt ggttccgggc tggggctggc
    25861 gatttgcctg aacattgttg aagcacataa cggccgcatt attgccgccc attcgccttt
    25921 tggcgggctt agcattacag tagagttacc gctggaacgg gatttacaga gagaagtatg
    25981 accgagttac caatcgacga aaacacaccg cgtattttga tcgtggaaga tgaaccgaag
    26041 ctggggcagt tgctcattga ttatctgcgt gctgcgagct atgcgccaac gttgattagc
    26101 cacggcgatc aggtactgcc atatgtgcgc cagacaccac cggatctgat cctgttggat
    26161 ctgatgctcc ctggcaccga tggcctgacg ctgtgccggg aaattcgtcg tttttctgac
    26221 attccgatcg tgatggtgac ggcaaaaatc gaagagatcg accgcctgct ggggttggag
    26281 attggcgcag atgactatat ctgcaagccg tacagcccac gggaagtggt agcgcgcgtc
    26341 aaaaccattt tgcgccgttg caaaccgcag cgtgagttgc agcaacagga tgctgaaagc
    26401 ccgttgatta tcgacgaagg tcgttttcag gcttcctggc gcggtaaaat gcttgacctg
    26461 acgcctgcag aatttcgact gctgaaaacg ctctctcatg aaccaggaaa agtgttctcc
    26521 cgcgagcagt tgctgaacca tctttatgac gactaccgcg tggtaaccga ccgtaccatc
    26581 gacagccaca ttaaaaacct gcgccgcaag ctggaatctc tcgacgccga acagtcattt
    26641 atccgcgccg tttacggcgt cggttaccgc tgggaagccg acgcctgccg catcgtttaa
    26701 catttttacc tgccggatct ggccttcaga ccagatccgg caacattatc ccacgcatag
    26761 tcagcaaact gacatgatct ctccgccctg gcaggcacca gaaaatcgct catactttaa
    26821 tcggcaaaca gtccttttag atgctgtttt cgatacgcaa tttcaatcaa ggagtcatta
    26881 tggctggttg gtttgaactc agtaagagca gtgataatca attccggttt gtgctaaaag
    26941 cgggcaatgg tgagactatc ctcaccagcg agctgtatac ctcaaaagcc tctgcggaaa
    27001 agggcatcgc gtcggtacgt agcaacagcc cgcaagaaga acgctatgag aaaaaaacgg
    27061 caagcaacgg caaattctat ttcaatctga aagccgccaa tcatcaaatt atcggctcca
    27121 gccagatgta cgccaccgcg caatctcgtg aaaccggaat tgcctccgtt aaagcaaatg
    27181 gcacaagcca gacggtgaaa gacaatacgt aattacgatg ccgggcgtag gttgttggcg
    27241 tccggcgctt taccagttac ctccacagcg ctacaatgcc cgcccttaaa gtgggggcac
    27301 tcccctgacc gcttcatcag gtgaagcgga tctgacctgt catcagaacg agagaattat
    27361 gtttaaaccg gaactccttt ccccggcggg aacgctgaaa aatatgcgtt acgctttcgc
    27421 ttatggcgca gatgctgttt atgcgggcca gccgcgttac tccctgcgtg tgcgcaacaa
    27481 cgaattcaac cacgaaaatc ttcaactcgg cattaacgaa gcccacgcgc tggggaaaaa
    27541 gttttatgtc gtggtcaaca ttgcaccgca caacgccaag ctgaaaacct ttatccgtga
    27601 cctgaaaccg gtggtggaaa tggggccgga tgcgctgatt atgtccgatc cagggctgat
    27661 tatgctggtg cgtgagcact tccctgaaat gccgatccat ctctcggtac aggctaacgc
    27721 cgtgaactgg gcgacggtga aattctggca gcaaatgggc ctgacccgcg tgatcctctc
    27781 tcgcgaactg tcactggaag agattgaaga gatccgcaat caggtgccgg atatggaaat
    27841 cgaaatcttc gttcacggcg cgctgtgcat ggcctactcc ggtcgctgcc tgctctctgg
    27901 ctatatcaac aagcgcgacc cgaaccaggg cacctgcacc aacgcctgcc gctgggagta
    27961 caacgtccag gaagggaaag aagatgacgt tggcaacatc gtacacaagt acgagccgat
    28021 tccggtgcaa aatgttgagc cgacgctggg tatcggcgcg ccaaccgaca aagtgtttat
    28081 gatcgaagaa gcccagcgtc cgggcgagta tatgaccgcg tttgaagatg agcacggcac
    28141 ttacatcatg aactcgaaag atctgcgcgc catcgcccat gttgaacgcc tgaccaaaat
    28201 gggcgtgcat tcgctgaaaa tcgaaggccg taccaaatct ttctactatt gcgcacgcac
    28261 cgcgcaggtt taccgtaaag ctatcgatga cgccgctgcg ggcaaaccgt tcgataccag
    28321 cctgctggaa actctggaag gtctggcgca tcgtggctat accgaaggtt tcctgcgtcg
    28381 tcatactcac gacgattatc agaactacga atacggttat tcagtttctg accgccagca
    28441 gtttgttggt gagtttaccg gtgagcgcaa gggggacctc gcggcggtag cggtgaaaaa
    28501 taaattctcc gttggcgaca gccttgagct aatgacgccg caaggcaaca ttaactttac
    28561 ccttgagcac atggaaaacg ccaaaggtga agctatgccg gtcgcaccag gcgatggtta
    28621 tactgtgtgg ctcccggtgc cgcaggatct tgagctaaat tacgcgctgc tgatgcgtaa
    28681 tttctccggg gaaaccacgc gtaaccccca cggtaagtga ttaatttcga ttatttttcc
    28741 cggatggaaa attcttagaa accgatcaca tacagctgca tttattaagg ttatcatccg
    28801 tttcgctgaa aaacataacc cataaaatgc tagctgtacc aggaaccacc tccttagcct
    28861 gtgtaatctc ccttacacag gcttattttt tatgcataag ccctatccct ggtcaccgtc
    28921 ttccattgac cacatcgata gaatctccct taatagcacg atgcctttca cttatcgaca
    28981 tcgtgctcgc acaggttccg gttacgcaca gccagaacgc gcatgtttga cgcttaccaa
    29041 aaaatgaacc taaagcattg gaatattttt gacatcattt tctgatggct gcataaaata
    29101 aaaattctgc tttagtttca tctatctgtt tgtcattatt actcacattc aataatggtg
    29161 ttgaagaata tcccatcaca gataaaataa atatgtgcat ggtagtcttg aatctattct
    29221 cactctccac atttgaatgt cagacgagca acgccatgta atcctgcacc ttctgtcttc
    29281 aatttaacta tctgcatttt tttgccctga gtaacacaga aatgggctgc atcatttttt
    29341 actatatttt ctgcaccaga tattctgccc ctggctaaag aagcttcggc ttcggtgtag
    29401 tattggttat cgagtttacg ctgaatatta cttttatatg caagaccaaa tttaccgata
    29461 cttgtctcat cattatgtac agcacaccca gacataagaa aaatactaat taatgatata
    29521 gcagctatct ttttcatctc accttccccc attaaatacc aacgacacgc tctggtgttt
    29581 aaatataata atggcatgat tattataatt gaataggatt ataataaatg ttctgtacaa
    29641 catttcctac ataagtagga attacagaca tagaggccct tccgggtaac cccatggggg
    29701 actttaatat attttgaata gtatattgaa gatgccactg tttagttgaa tattaggtat
    29761 attctctttt ttaaaattta tcagtggcta ccgttaatat tcgctgtccc cattgtaagg
    29821 tcctggtggt aagcactgaa tccccatacc tgaactgact ttttatcctc cgactttcat
    29881 cctgttctga ctccaccttt tcttttctgc tctacactat ctacagacca atcataaagg
    29941 cacatacgat catggcagaa tttcccgcca gcttactgat tcttaatggc aaaagtactg
    30001 acaatctacc cttgcgcgaa gcaattatgc tgttgcgtga ggaaggaatg acgatccatg
    30061 tgcggatcac ctgggagaaa ggcgatgctg cacgatttgt agaggaggcc cggaagttag
    30121 gcgtcgcaac agtgattgcc ggtggtggcg atggcaccat taatgaagtt tctacggcat
    30181 tgattcaatg tgagggggat gacatacccg cgctgggaat tttaccatta ggaactgcca
    30241 atgattttgc cactagtgta gggattcctg aggcactgga taaggcgctg aaactggcaa
    30301 ttgccggtaa cgccattgcg atagatatgg cgcaggtcaa caaacaaacc tgttttatta
    30361 atatggcgac aggcgggttt gggacgcgta ttaccacaga aacgccggaa aaattaaaag
    30421 ccgcgctggg tggcgtctct tacatcattc atggcttaat gcgcatggac actctgcaac
    30481 cggaccgttg tgaaatccgc ggtgaaaact ttcactggca aggtgacgcc ctggtcattg
    30541 gtattggtaa cgggcgtcag gccggtggcg gtcaacaatt gtgcccgaac gcattaatta
    30601 acgatggctt gctgcaactg cgcattttta ccggcgatga aattattccg actctcgtat
    30661 caaccttaaa atctgacgaa gataacccga atattatcga aggtgcttcg tcgtggtttg
    30721 atatacaagc cccacacgaa atcactttta atcttgatgg cgaaccgttg agtgggcaaa
    30781 acttccatat tgaaatactt ccggcggcgt tgcgttgtcg attaccacca gattgtccat
    30841 tgttgcgtta atcaaactat tctctgttga accagagaga atccgtaatg ccggatacgg
    30901 tgtaaacacc ttatccggca tacagaacaa tactacaccg taattaattt tacccgtgtc
    30961 ttctgcaatg ccagtttatc cacctcagac acagcatcat cggtaataat aatgtcaatt
    31021 ttttcgattg gcagtacctg attaaaaccg cgacgattaa atttcgatga atcaagaacg
    31081 gcaatcactt tattcgccgc tgtcaccatc gcaccgctaa cggaataacc ttcattaaag
    31141 gtcgtaatac cattaaccgc atcaatacca tcagcaccga caaacattaa atcggcatta
    31201 atatcctgca gggaacgttc agcaatagat ccatgcatcg agcgcgtttt atggcggacc
    31261 gtgccaccgc agacgaccag agtaatgtct ttattttcgg aaagggcaaa cgccgccggg
    31321 agactgttgg taatcaccgt gatatttttg gcggtcatta atccttcggc gataagcatt
    31381 gtggtacttc cgctgtcgag aataacggtc atcccttcgt ggatcatttt gactgccgcc
    31441 tgcgctattc tgtttttcgg cgcgctggcg agctgaaatc gctctttaaa cccgacttcc
    31501 tgggtctcgg tttcgctatt acctgacatt attttcgccg caccgccatg aaagcgcgta
    31561 accacgcctt tttgttcgag aaagcgcaaa tcggcacgga ttgtcgcttc cgaggcagca
    31621 aatactcccg ccagatcctg aacaagcacg gttccctgtt cattcactaa ttggatgatc
    31681 ttattccttc gctcgaatga attcatcgtc atttacccat attcaattgt ggctagtgta
    31741 aacgaagggg aaccattggt gaatgatctg ttttgcacaa taccgggcca gcatcacgct
    31801 ggcccgcggt ttcagggaat gagcaacact ttgcccggca tagcattacg agcgatgtca
    31861 cgcaccgcct gggcaaagct ttcaaagctt ccacggtgag cgattaatgg ctccaggctt
    31921 aacttacgtt ctgtcagcaa ccggctcgcc gtttcccact cctgccccgg ccaagggctg
    31981 gagtagttca tccaactgcc gataaccgtc agctctttac gcaatatttt gccaaacgtt
    32041 gcagatgtta aatgcagatc ctgatgcaac gtgcccacca gcgccagttg ggcatgagga
    32101 ccggcaatct ctaccgccag ttcgacggtt tgcgggacgc cagccgtctc gaggataagc
    32161 tgattaaagc gcagctcgcg taaaacgccc tgtatttgcg gcgcgctcat ttcacggctg
    32221 ttaaatgttt gcatcgcacc gaaagatttt gccagtgcca gtttttctga gctaatgtcg
    32281 atagccgtca cactctttgc tcccagcgcg acagcgcact gaattgccag caggccaatg
    32341 gttccggcac caataataat aacgttttta ttctcacatc cttgcgctaa atggaacgca
    32401 tgcaggccaa cggtaatcgg ttcaataaaa gcgccatcct caataggcat atccgcaggt
    32461 agtgcaaaga cattgtttcg cttaacgaca atatattcgg caaatccacc atcacgccgt
    32521 gagccaataa aatcatattt tgcgcactgg gaataaaacc ctttcagaca ctctggacaa
    32581 gtaaaacagg gtaataacgg cacacaggca accgcatcgc cggggtgtaa atcatcaaca
    32641 ccggatccca ccgcatcaat atagccacta aattcatggc ctaacgttat tggataataa
    32701 tgtgcaccat ttttaaatat cctgggtaaa tcggaaccac ataagcccga gctggcaatt
    32761 tttacccgca cctcatcctg atgtttaatt tcaggaatga cgctt
//
LOCUS       DAPOXO010000061        32457 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.061, whole genome shotgun sequence.
ACCESSION   DAPOXO010000061 DAPOXO010000000
VERSION     DAPOXO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32457
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.061"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            189..296
                     /locus_tag="ROH59_003217"
     CDS             189..296
                     /locus_tag="ROH59_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HDX4805663.1"
                     /translation="MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            complement(382..2061)
                     /gene="bcsG"
                     /locus_tag="ROH59_003218"
     CDS             complement(382..2061)
                     /gene="bcsG"
                     /locus_tag="ROH59_003218"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HDX4805664.1"
                     /translation="MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFAAFLLMPIPHYSLHRLRHWIALPIGFALFWHDTWLPGPESIMSQGSQVAGFS
                     TDYLIDLVTRFINWQMIGAIFVLFVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFS
                     LWPAGQPTTTVTTTGGNAAATVAATGGAPIVGDMPAQTAPPTTANLNAWLNNFYNAEA
                     KRKSIFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATS
                     YSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLK
                     EVRENGGMQSELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNT
                     LPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIDQPSSFLAISDLVVRVLDGK
                     IFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ"
     gene            complement(2058..2249)
                     /gene="bcsF"
                     /locus_tag="ROH59_003219"
     CDS             complement(2058..2249)
                     /gene="bcsF"
                     /locus_tag="ROH59_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HDX4805665.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            complement(2246..3817)
                     /gene="bcsE"
                     /locus_tag="ROH59_003220"
     CDS             complement(2246..3817)
                     /gene="bcsE"
                     /locus_tag="ROH59_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HDX4805666.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKITLFSMLNHEKGLYYLARDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINSGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGCWTLVQHQEAE
                     IQPRSDEKRILSNVAVLEGAPPLSEHWQLFNNNEVLFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLAQSSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            4090..4278
                     /locus_tag="ROH59_003221"
     CDS             4090..4278
                     /locus_tag="ROH59_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HDX4805667.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDILALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            4290..5042
                     /gene="bcsQ"
                     /locus_tag="ROH59_003222"
     CDS             4290..5042
                     /gene="bcsQ"
                     /locus_tag="ROH59_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HDX4805668.1"
                     /translation="MAVLGLQGVRGGVGTTTITAALAWSLQMLGENVLVVDASPDNLL
                     RLSFNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRL
                     SDICSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQ
                     ALPDGAHILINDFRIGSQVQDDIYQLWLQSQRRLLPMLIHRDEAMAECLAAKQPVGEY
                     RSDALAAEEILTLANWCLLNYSGLKTPVGSAS"
     gene            5039..7657
                     /gene="bcsA"
                     /locus_tag="ROH59_003223"
     CDS             5039..7657
                     /gene="bcsA"
                     /locus_tag="ROH59_003223"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HDX4805669.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGASRKETPKPR
                     RRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGTRRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLFHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYIYGPPTEMLTVVVSMVWVFYNLIIL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPAQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            7668..10006
                     /gene="bcsB"
                     /locus_tag="ROH59_003224"
                     /pseudo
     CDS             7668..10006
                     /gene="bcsB"
                     /locus_tag="ROH59_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
     gene            10013..11119
                     /gene="bcsZ"
                     /locus_tag="ROH59_003225"
     CDS             10013..11119
                     /gene="bcsZ"
                     /locus_tag="ROH59_003225"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
                     /protein_id="HDX4805670.1"
                     /translation="MNVLRSGLVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVID
                     PSDARKITTSEGQSYGMFFALAANDRAAFDNLLDWTQNNLAQGSLKENLPAWLWGKKE
                     NSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
                     SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFS
                     PDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTE
                     KNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNY
                     VLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH"
     gene            11101..14574
                     /gene="bcsC"
                     /locus_tag="ROH59_003226"
     CDS             11101..14574
                     /gene="bcsC"
                     /locus_tag="ROH59_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
                     /protein_id="HDX4805671.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVIAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADTPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVQALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HNSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAYIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKPNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQE
                     LVNRLQNDQVLETANRLRENGKEAEAEALLRQQPPSSRIDLTLADWAQQRRDYTAARA
                     AYQNVLTREPTNADAILGLTEVDIAAGDKAAARSQLAKLPATDNASLNTQRRVALAQA
                     QLGDTAAAQQTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPMQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            14656..16644
                     /gene="hmsP"
                     /locus_tag="ROH59_003227"
     CDS             14656..16644
                     /gene="hmsP"
                     /locus_tag="ROH59_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HDX4805672.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPPQDLVGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPEDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            16827..18113
                     /gene="dctA"
                     /locus_tag="ROH59_003228"
     CDS             16827..18113
                     /gene="dctA"
                     /locus_tag="ROH59_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HDX4805673.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            18333..19829
                     /locus_tag="ROH59_003229"
     CDS             18333..19829
                     /locus_tag="ROH59_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDX4805674.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLDAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAAWDQIMAPSTAAAATSVATDDVHPEVTDIPPAQ"
     gene            complement(19925..20854)
                     /gene="kdgK"
                     /locus_tag="ROH59_003230"
     CDS             complement(19925..20854)
                     /gene="kdgK"
                     /locus_tag="ROH59_003230"
                     /EC_number="2.7.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HDX4805675.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWRGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSATICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAEDAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            21086..21853
                     /gene="pdeH"
                     /locus_tag="ROH59_003231"
     CDS             21086..21853
                     /gene="pdeH"
                     /locus_tag="ROH59_003231"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HDX4805676.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFVEHGLLA
                     SVNIDGPTLIALRQQPKILRQIEELPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            21923..23983
                     /locus_tag="ROH59_003232"
     CDS             21923..23983
                     /locus_tag="ROH59_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312431.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDX4805677.1"
                     /translation="MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLEKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLSFSEVTGSKGKADKEKVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGG
                     VDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGD
                     SDIHGSLIYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKS
                     VQPAGKVLPYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQP
                     LKFGIAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAE
                     LRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNC
                     AAANLDIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILS
                     QMKK"
     gene            complement(24162..25484)
                     /locus_tag="ROH59_003233"
     CDS             complement(24162..25484)
                     /locus_tag="ROH59_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HDX4805678.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFTPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVSSI
                     LGASVAPYIAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(25877..26890)
                     /gene="yhjD"
                     /locus_tag="ROH59_003234"
     CDS             complement(25877..26890)
                     /gene="yhjD"
                     /locus_tag="ROH59_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HDX4805679.1"
                     /translation="MTQENEIKRPTQDLEHEPIKQLDNSEKGGKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGVAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQP"
     gene            complement(26938..27837)
                     /locus_tag="ROH59_003235"
     CDS             complement(26938..27837)
                     /locus_tag="ROH59_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417978.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4805680.1"
                     /translation="MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQL
                     GTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPSGI
                     AKSLLLPRLSEFLYLHPGIELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGK
                     LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGS
                     MLTVNSSENYLAAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQR
                     RELSRRVNLFMQWLAGVMKEYLD"
     gene            28357..28959
                     /locus_tag="ROH59_003236"
     CDS             28357..28959
                     /locus_tag="ROH59_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDX4805681.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQHRIPGVSIQGASQADELWQKLES
                     YPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLITATDCNKRWLQEVIHFNVLAIVP
                     RDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
                     EIGRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS"
     gene            complement(29010..30659)
                     /locus_tag="ROH59_003237"
     CDS             complement(29010..30659)
                     /locus_tag="ROH59_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDX4805682.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARNWLKTVNQFYLEQHKLI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            31064..>32457
                     /gene="ccp"
                     /locus_tag="ROH59_003238"
     CDS             31064..>32457
                     /gene="ccp"
                     /locus_tag="ROH59_003238"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HDX4805683.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LANKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKAQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYMPYMQDK"
BASE COUNT         7776 a         8134 c         8892 g         7655 t
ORIGIN      
        1 ggcaagccgg aaaggttccg gtgaggcgca atgttgcggg ggctttatcc ctggtggcat
       61 tggttgctgg agagagaaaa cccccgtacg ttgcaggtat gcacctgaca acatcacggg
      121 ggctaatctt gaaccttaac aactcaagaa tagccgcgaa acgttgtcat tacaacacag
      181 gcggctatat gacgctcgca gagctgggca tggccttctg gcatgattta gcggctccgg
      241 tcattgctgg cattcttgcc agtatgatcg tgaactggct gaacaagcgg aagtaacgtg
      301 tcatgcgggc gtcaggctgc cgtaatggca atttgcgccc ggaccaggcc gcagggggaa
      361 actctgcggc ctttttcgtt cttactgcgg gtaaggcacc cagtcgccgc cgttcaggcg
      421 aacgtacggt ttatcctggt attgaataac tactgcattt gagttctcgg agaccggtgc
      481 tgtttgtggt aacccactgg tgagtttttt ccagtcaaca ttgtcttcgg tgaaaatctt
      541 gccatcaaga acgcgaacca ccagatcgga gatagccagg aagctgctcg gttggtcgat
      601 gacaatcgga gccccctgat gtggtgcctt catgccgaag aatttcaccc caacggggac
      661 gtctgtgata gacgggctag ggatatcacg tagaccagat acctgcattc tgtcgccctt
      721 cagcgcgccg ccgtgttccg gcaccacgac caccatcact ttacgacccg atttctccag
      781 ttcagtaaag aaggcgtcca gttcatcaaa gaatttttgc gcccgcgctt tgtaatccgc
      841 tgttttgctg acgcccggat aatggttgcc gtcatgcagt ggaagcgtgt tgtagaacgt
      901 ggcactacgg ctgtttttat ctttttcggt aacgtccagc caacggttaa gcacggcggt
      961 atcgtcataa accggcgaac catcaaagcc cagcaaaata accggcagat ttgtttgatc
     1021 catcaattcg ctctgcatgc cgccattttc gcgaacttcc ttcaaaaaac caccgaactg
     1081 gccgttatgt cccatcatca ggtgctgggt aaagcccagt ttcgacaggt tatcaaacag
     1141 atagcagtcg ttatttgccg gttgatacag attagtgtgc gaagtctgcc cgcagctggc
     1201 gcgcagtaaa cggatcgccg ccgggccact gtaggaggtg gcggagttaa agttcttgaa
     1261 ctcaatatcg aaatgcgacc acagtggatg cgacatcaat ccggcggctt caatatccga
     1321 ccaggaaagc gaacagatat taatcaccag tagttcaaat ggctgagcat cagcgggcag
     1381 cgaagacggg aagatcgatt tacgtttcgc ctccgcgtta tagaaattat tcagccaggc
     1441 gttaaggttt gctgttgttg gcggtgcagt ttgtgcgggc atatcaccca ctatcggtgc
     1501 gccacccgtc gccgcaacgg ttgccgctgc gttaccaccc gtcgttgtta cagtggtcgt
     1561 tggttgaccg gctggccaca aggagaaact tggtcccgcc agggtaagta cgttcagcca
     1621 tagcagaatg gcaaccacaa aaacggtaat gcgaatccat tgtgacagga ataaccaggc
     1681 cacgaataaa acaaaaatgg ccccaatcat ctgccagtta ataaagcgtg tgacaagatc
     1741 gattaaataa tcggtactga accccgccac ctgcgaaccc tggctcatta tgctttccgg
     1801 accaggcaac caggtgtcat gccagaacaa agcaaagccg atcggcaggg caatccagtg
     1861 gcgcaagcga tgcaggctat agtgcggaat gggcatcagt agaaacgcgg caaacaccaa
     1921 attgaggagc ggatggaagt taagatatcc cgcccacaac aggccgaact taaccagaaa
     1981 atagaagttc cagccggaaa ggccgcgcca gtattgccag agggaagaag gcatggcggt
     2041 attttgcgta aattgagtca ttttttggtt gccctggctt tttccgtgcg gcgtaacgtc
     2101 ccggccggtt taacataacg aggtttagca aagaacaaac gtaaggtgtc gcgaatgcgt
     2161 cgcaaagagt gccgcgccag atagcccagc gggaaaaata tcagtgcgca aacgacaata
     2221 atttcaatga tatcgctgat ggtcatcatg atgagcgctc cacagcatca tctaacagtc
     2281 gcattggttc tggtattcgt cgccagtggc gaccatcatg ctcggcattg atgaccggtt
     2341 tagaactttg cgctaaaggc agcggcatgc cccattgttc tggggcaagc aggcgcatct
     2401 gcaccagctc ggcactgatt tgatcatctt caaaccagac cattcggttt gagaaaatgt
     2461 cgccagtagg caatgggaaa atatgattca acgcggtatc cagatcgtta atccgacaga
     2521 atgagagaaa cagcaccagc cgattaccgc caatggtcat gatatcgccg gtacggttag
     2581 ggcgacatag cgtcagggct tgctcaacgc ggatacccgg taccggacgt agggcaacca
     2641 gaacgccttt accgtgggca ggtaatagag ggttattcat catgttgttg acggcattac
     2701 agaacacatc ccacttctgg aaaccacgca gtttgagcgg ctgggtcatt gacagcaagg
     2761 tagtgatatc ttccggcaca tagcgactaa acttctgccc ttgcacgctt tcgatcatcg
     2821 tcagacagcg ggagagtggc gcattccacg ggataaccat atttgcaccg caggccaata
     2881 ataaacgttc atcggtggcg cgcaggctgg cggtattttc ccgtacgagg attttcatcg
     2941 cactaccgcg ctggcgacgc agagtatgaa tgctgcgggc cagtggctcg atttgcgcat
     3001 tttgctgtaa agaaaagacc accgtcgccg cctgagcggt acgggcttca ttgaacagga
     3061 cttcgttatt gttgaacagt tgccagtgtt ccgatagcgg cggcgcacct tccagtacag
     3121 caacattact cagaatgcgt ttttcgtcgc tgcgtggttg gatttccgcc tcttggtgtt
     3181 gaactaatgt ccagcaacca ttttgttgct gaacgctaag ttgctgacgg gcgctgaccc
     3241 ctttttcgtt gcaccagaaa gcaatatcca gcaaatgttg gtcgccctga aaacgcaaac
     3301 tggcaagacc aaaaagtgac cgatattcct caagtaacaa tgaaaattgt ttatcgttat
     3361 tatttccgga attaattacc aaaagcgaac aatggtttag ccggctccat ttattcattt
     3421 tatccaacca tgagcgaagc cgctcggcag gaatgttttg ccatgcatta tttgcgcaaa
     3481 caagaataaa aaggtaatta tggggatcaa tagaacactg caaatcacgg gccaaatagt
     3541 atagaccttt ttcatgattt agcatcgaaa ataatgttat tttttccggc ccttgagaat
     3601 catctaattg aaagattttc gctggatcgc tgtccatgct aatgaccgcg acgtgtgcgg
     3661 tttcagcctg ggatgcaatt gtttgattcg ccagactgat agcatcttca tggcgatcga
     3721 cgttaaacca ccagacgccg cctgctggca tatgtcgcag ctcatcccat aatgatgaga
     3781 taccgataga gaatacaggg tccacaatgt ccctcatgtc aacattttgt ctgattatca
     3841 gtttactagc gaaagctaag aaataaacct accattgaaa ttaaaactta tcagatttag
     3901 catgtgaatc aatttagcag gtcacaagac atgtgatttt agtcttttcg tttttaactt
     3961 tttctgttgc ataacggaaa gtcaaaaagt gagcacattc ccgtctcgcc gtaaacaata
     4021 aaccgacgaa atgctcacag ttagaattgt ctcatgaacg gtacggttat ttcataggga
     4081 tcaagaaaaa tgaataacaa tgaaccagat actctgcctg atcccgcgat aggctatatc
     4141 ttccagaatg atattttggc gttaaagcag gcattttcac tgcctgatat tgattatgcc
     4201 gatatttccc aacgcgaaca gttggccgcg gcattaaaac gctggccgtt gctggcagag
     4261 tttgcgcaac aaaagtaggg gattggtgaa tggccgtact gggattgcag ggggttcggg
     4321 gaggcgtggg gacaacaacc atcaccgccg cattagcctg gtcattacaa atgttgggag
     4381 aaaatgtcct ggtggtcgat gccagcccgg acaacttgtt gcgcctgtca tttaacgttg
     4441 attttaccca ccgtcagggt tgggccagag ctatgctgga tggccaggac tggcgtgacg
     4501 ccgggttgcg ctatacctcg cagctcgatt tgctgccttt tggtcagtta tcgattgaag
     4561 aacaagaaaa tccacagcac tggcaaaccc ggctgagcga tatttgctcc ggcttacagc
     4621 aactaaaagc cagcgggcgt taccagtgga ttttaattga cttaccgcgt gatgcctcgc
     4681 agataaccca ccagctgctg agtttgtgcg atcactcgct ggcaatcgtc aatgtggatg
     4741 ccaactgcca tatccgactg catcagcaag cgctgccgga tggtgcacat attttgatta
     4801 atgacttccg tattggcagc caggttcagg acgatattta ccagctttgg ttgcaaagcc
     4861 agcgccgatt gctgccgatg ctcattcatc gtgatgaagc gatggctgaa tgtctggcag
     4921 ctaagcaacc agtcggtgaa tatcgcagtg atgcgctggc ggctgaagag atactgacgc
     4981 tggcgaactg gtgcctgttg aattattccg ggctgaaaac gccagtcggg agtgcatcat
     5041 gagtatcctg acccggtggt tgcttatccc gccggtcaac gcacggctta ttgggcgtta
     5101 tcgcgattat cgtcgtcacg gcgcgtcggc tttcagcgcg acgctcggct gtttctggat
     5161 gatcctggcc tggattttta ttccgctgga gcacccgcgc tggcagcgta ttcgcgcaga
     5221 acataaaaac ctgtatccgc atatcaacgc ctcgcgtccg cgtccgctgg acccggtccg
     5281 ttatcttatt caaacatgct ggttactgat cggtgcatcg cgcaaagaaa cgccgaaacc
     5341 gcgcaggcgg gcattttcag gtctacaaaa tattcgtgga cgttaccatc aatggatgaa
     5401 tgagctgcct gagcgcgtta gccataaaac acagcatctt gatgagaaaa aagagctcgg
     5461 tcatttgagt gccgggacgc ggcggttgat cctcggtatc atcgtcacct tctcgctgat
     5521 tctggcgtta atctgcgtta ctcagccgtt taacccgcta gcgcagttta tcttcctgat
     5581 gctgctgtgg ggggtagcgc tgatcgtacg gcggatgccg gggcgcttct cggcgctgat
     5641 gctgattgtg ctgtcgctga ccgtttcttg ccgttatatc tggtggcgtt acacctcgac
     5701 gttaaactgg gacgatccgg tcagcctggt gtgcgggctt attctgctct tcgctgaaac
     5761 gtacgcgtgg attgtgctgg tgctcggcta tttccaggtc gtatggccgc tgaatcgtca
     5821 gccggtgcca ttgccgaaag atatgtcgct gtggccgtcg gtggatatct ttgtcccgac
     5881 ttacaacgaa gatctcaacg tggtgaaaaa taccatttac gcttcgctgg gtatcgactg
     5941 gccgaaagac aagctgaaca tctggatcct cgatgacggc ggcagggaag agtttcgcca
     6001 gtttgcgcaa aacgtggggg tgaaatatat cgcccgtacc actcatgaac atgcgaaagc
     6061 gggcaacatc aacaatgcgc tgaaatatgc caaaggcgag ttcgtgtcga tattcgactg
     6121 cgaccacgta ccaacgcgat cgttcctgca aatgaccatg ggctggttcc tgaaagagaa
     6181 acagctggcg atgatgcaga cgccgcacca cttcttctcg ccggatccgt ttgaacgcaa
     6241 cctggggcgt tttcgtaaaa cgccgaacga aggcacgctg ttttatggtc tggtgcagga
     6301 cggcaatgat atgtgggatg ccactttctt ctgcggttca tgtgcggtga ttcgccgtaa
     6361 gccgctggat gagattggcg gtattgctgt cgaaacggta accgaagatg cgcacacttc
     6421 tctgcgtctg caccgtcgtg gctacacctc agcgtatatg cgtattccgc aggcagcggg
     6481 gctggcgacc gaaagtctct cggcgcatat cggtcagcgt attcgctggg cgcgcgggat
     6541 ggtgcaaatc ttccgtctcg ataacccgct caccggtaaa gggctgaagt ttgctcagcg
     6601 gctgtgctat gtcaacgcca tgttccactt cttgtcgggc attccacgac tgatcttcct
     6661 gactgcgccg ctggcgttcc tgctgtttca tgcctacatc atctacgcgc cagcgttgat
     6721 gatcgccctg ttcgtgctac cgcatatgat ccatgccagc ctgactaact cgaagatcca
     6781 gggcaaatat cgccactctt tctggagtga aatctacgaa acggtgctgg cgtggtatat
     6841 cgcaccaccg acgctggtgg cgctgattaa cccgcacaaa ggcaaattta acgtcaccgc
     6901 caaaggtgga ctggtggaag aagagtacgt cgactgggtg atctcgcggc cctacatctt
     6961 ccttgttctg ctcaacctgg tgggcgtagc ggttgggatc tggcgctaca tctatggtcc
     7021 gccaaccgag atgctcaccg tggtcgtcag tatggtgtgg gtattctaca acctgattat
     7081 tctcggcggc gcagtcgcag tatcggtaga aagcaaacag gtacgccgat cgcaccgcgt
     7141 ggagatgacg atgcccgcag caattgcccg cgaagatggt cacctcttct cgtgtaccgt
     7201 tcaggatttc tccgacggtg gtttggggat caagatcaac ggtcaggcgc agattctgga
     7261 agggcagaaa gtgaatctgt tgcttaaacg cggtcagcag gaatacgtct tcccggctca
     7321 ggtggcgcgc gtgatgggta atgaagttgg gctgaaatta atgccgctca ctacccagca
     7381 acatatcgat tttgtgcagt gtacgtttgc ccgtgcggat acatgggcgc tctggcagga
     7441 cagctacccg gaagataagc cgctggaaag tctgctggat attctgaagc tcggcttccg
     7501 tggctaccgc catctggcgg aatttgcgcc ttcttcggtg aagggcatat tccgtgtgct
     7561 gacttctctg gtttcctggg ttgtatcgtt tattccgcgc cgcccggagc ggagcgaaac
     7621 ggcacaacca tcggatcagg ctttggctca acaatgatga taacgcgatg aaaagaaaaa
     7681 tattctggat ttgtgcagtg gctctgggga tgagtgcgtt cccctctttc atgacgcagg
     7741 cgacgccagc aacgcaacca ctgatcaatg ctgagccagc tgtagccgcc caggcggagc
     7801 aaaatccgca ggtggggcaa gtgatgccgg gcgtgcaggg cgcagatgcg ccagtcgtgg
     7861 cgcagaacgg tccttcccgt gatgtgaagc tgacctttgc gcaaattgcg ccgccgccgg
     7921 gcagcatggt gctacgtggc attaacccga acggcagcat tgagtttggt atgcgcagcg
     7981 atgaagtggt gacgaaggcg atgccaacct cgaatacacg ccatcgccat cattactgcc
     8041 tgtccagtcg cagttaaagg tttatctcaa tgatgaactg atgggcgtgc tgccagtgac
     8101 caaagaacag ttgggtaaaa aaacgctggc acaaatgccc attaacccgc tgtttattac
     8161 tgatttcaac cgtgtgcggc tggagtttgt cggccattat caggacgtgt gcgaaaaccc
     8221 ggccagcacc acgctttggc tggatgttgg gcggagcagt ggactggatc tgacctatca
     8281 gaccctgaat gtgaagaatg acctgtcaca cttcccggtg ccattctttg acccgcgtga
     8341 taaccgcacc aacaccttgc cgatggtctt tgcgggtgcg ccggatgttg agctgcaaca
     8401 agcatctgcc attgtcgcct cgtggtttgg ttcgcgttct ggctggcgtg ggcagaactt
     8461 cccggtgctc tataaccaac tgccggatcg caatgccatt gtctttgcca ccaatgacaa
     8521 acgcccggac ttcctgcgcg atcatccggc ggtaaaagcc ccggtgattg agatgattaa
     8581 ccatccgcag aatccttacg tcaaactgct ggtggtgttt ggtcgtgacg acaaagacct
     8641 gttgcaggca gcgaaaggta tcgctcaggg taacattctg ttccgtggtg aaagtgtggt
     8701 agtgaatgaa gtgaaaccgc tgctaccgcg taaaccgtac gatgcgccga actgggtgcg
     8761 taccgatcgt cctgtcacct ttggtgaact gaaaacctat gaagaacaat tacaatccag
     8821 cggtcttgag ccagcagcga ttaacgtttc gctaaacctg ccgccggatc tctacctgat
     8881 gcgcagtacc ggcattgata tggatattaa ttaccgctac accatgccgc cggtgaaaga
     8941 cagttcgcgg atggatatca gcctgaataa ccagttcctg caatccttca acctgagcag
     9001 caaacaggag gcgaaccgcc tgctgctgcg tattccggta ttacaaggtt tgctggatgg
     9061 caaaacggat gtctctattc cggcgctgaa actgggcgcg accaaccagt tgcggttcga
     9121 ctttgagtat atgaacccga tgccgggcgg ttcggtggat aactgtatta ccttccagcc
     9181 ggtgcagaat catgtggtga ttggtgacga ctccaccatc gacttctcga agtattacca
     9241 cttcatcccg atgccggatc tacgcgcctt tgctaacgcg ggcttcccgt tcagccggat
     9301 ggcggatttg tcgcaaacca tcaccgtgat gccgaaaacg ccaaacgaag cacagatgga
     9361 aaccttgctg aataccgttg gctttatcgg tgcgcagacg ggcttcccgg cgattaacct
     9421 gacggtgacc gatgatggca gcaccattca gggcaaagat gccgacatca tgatcgtcgg
     9481 tggtatcccg gacaaactga aagacgataa gcagatcgac ctgttggtgc aggcgaccga
     9541 aagctgggtg aaaacgccga tgcgccagac cccgttcccc ggtattgtgc cggacgagag
     9601 cgatcgcgcg gcagaaaccc agtcaacgct gacctcttcc ggtgcgatgg cggcggtgat
     9661 tggcttccag tcgccgtata acgaccagcg cagcgtgatt gcgctgctgg cagatagccc
     9721 acgcggttat gaaatgctta acgatgcggt gaacgatagc ggcaaacgcg ccaccatgtt
     9781 cggttcggtc gcggtgatcc gcgagtccgg tatcaacagc ctacgtgttg gcgatgttta
     9841 ttacgtaggt catctgccgt ggttcgagcg cttgtggtat gcgctggcaa accatccgat
     9901 tctgctggcg gtgctggcgg ctatcagtgt gatattgctg gcgtgggtac tgtggcgtct
     9961 gctgcgtatt attagtcgtc gtcgtcttaa cccggataac gagtaattga agatgaatgt
    10021 gttgcgtagt ggactcgtga cgatgctgct gctggctgcc tttagtgttc aggcagcctg
    10081 tacctggcct gcctgggagc agtttaaaaa ggattacatc agtcaggaag ggcgcgtcat
    10141 cgaccccagc gacgcgcgca aaatcaccac ctccgaaggg caaagttacg gcatgttctt
    10201 tgccctggcg gctaacgacc gtgcagcttt cgataatctt ctcgactgga cgcagaacaa
    10261 tctcgctcag ggttctttaa aagaaaattt gcccgcctgg ctgtggggca agaaagagaa
    10321 cagtaagtgg gaagtgctgg acagcaattc ggcctccgat ggtgatgtct ggatggcctg
    10381 gtcgttgctg gaggcggggc gtttgtggaa agagcagcgt tataccgaca tcggcagcgc
    10441 attgctaaaa cgtatcgcgc gggaggaagt ggtgacggtg cctgggctgg gctccatgtt
    10501 gttaccgggc aaagtgggtt ttgctgagga taacagctgg cgttttaacc ccagctacct
    10561 gccgccgacg ctggcgcagt atttcacccg ctttggcgcg ccgtggacca cgctgcgcga
    10621 aaccaatcaa cgtttattgc tggaaaccgc cccgaaaggc ttttcgccag actgggtgcg
    10681 ctatgagaaa gacaaaggct ggcagctaaa agccgaaaaa acgttgatca gcagctacga
    10741 cgctatccgc gtttacatgt gggtaggcat gatgcctgac agcgatccgc aaaaagcgcg
    10801 gatgctcaac cggtttaaac cgatggcgac attcactgag aaaaacggtt atccgccgga
    10861 aaaagtggat gtggctacgg ggaaagcgca gggtaaagga ccggtcggtt tttctgccgc
    10921 catgctgccc tttttacaaa accgcgatgc gcaggccgtt cagcgccagc gcgtggccga
    10981 taactttccc ggcagcgatg cctattacaa ctatgtgctg accctgtttg gacaaggctg
    11041 ggatcaacac cgtttccgct tctcgacaaa aggtgagtta ttacctgact ggggccagga
    11101 atgcgcaaat tcacactaaa catattcacg ctttccctcg gtctggccgt catgccgatg
    11161 gtcgaggcag caccaaccgc tcagcaacag ttgctggagc aagttcggtt aggcgaagcg
    11221 acccatcgtg aagacctggt gcaacagtcg ttgtatcggc tggaacttat tgatccgaat
    11281 aacccggatg tgattgctgc ccgttttcgt tctctgttac gtcagggcga tattgatggc
    11341 gcacaaaaac agctcgatcg gctgtcgcag ttagcgccga gttcaaatgc gtataaatcg
    11401 tcgcggacta cgatgctgct ttccacgccg gatggtcgtc aggcactgca acaggcaaga
    11461 ttgcaggcaa ctaccggtca tgcggaagaa gctgtggcga gttacaacaa actgttcaac
    11521 ggtgcgccgc cggaaggtga cattgctgtc gagtactgga gtacggtggc gaaaattccg
    11581 gctcgccgtg gcgaagcgat taatcagcta aagcgcatta atgcggatac gccgggcaac
    11641 acgggcctgc aaaacaatct ggcgctattg ctgtttagta gcgatcgccg tgacgaaggc
    11701 tttgccgtcc tggaacaaat ggcgaaatcg aacgccgggc gcgaaggggc ctctaaaatc
    11761 tggtacgggc agattaaaga catgcccgtc agcgatgcca gcgtgcaggc actgaaaaaa
    11821 tatctctcga tctttagcga tggcgatagc gtggctgctg cgcaatcgca actggcagaa
    11881 cagcaaaaac agctggccga tcctgctttc cgcgctcgtg cgcaaggttt agcggcggtg
    11941 gactctggca tggcgggtaa agccattccc gaactacaac aggcggtgcg ggcgaacccg
    12001 aaagacagtg aggctctggg ggcgctgggc caggcgtatt cccagaaagg tgatcgcgcc
    12061 aatgcagtgg cgaatctgga aaaagccctc gcgctggatc cgcacaacag caataacgac
    12121 aaatggaaca gtctgctgaa agtaaaccgc tactggctgg cgatccagca gggcgatgcc
    12181 gcgctgaaag ccaataatcc tgaccgggca gaacggctgt tccagcaggc acgtaatgtc
    12241 gataacaccg acagctatgc agtgcttggg ctgggcgatg tggcgatggc gcgcaaagat
    12301 tatcccgccg ccgaacgcta ttaccagcag accttgcgta tggacagcgg caacactaac
    12361 gccgtgcgcg ggctggcgaa tatttaccgc cagcagtcgc cagaaaaagc cgaagcgtat
    12421 atcgcatcgc tctctgccag ccagcggcgc agcattgatg atatcgaacg cagcctgcaa
    12481 aacgaccgtc tggcacagca ggcagaggca ctggaaaacc aggggaaatg ggcgcaggcg
    12541 gcagcacttc agcggcaacg actggcgctg gaccccggca gtgtatggat tacttaccga
    12601 ctttcgcagg atctctggca agccggacaa cgcagccagg ccgatacgtt aatgcgcaat
    12661 ctggcgcagc agaagccgaa cgacccggag caggtttacg cttacgggct gtatctctcc
    12721 ggtcacgacc aggacagagc ggcgctggcg catatcaaca gcctgccgcg cgcgcagtgg
    12781 aacagcaata ttcaggagct ggttaatcga ctgcaaaacg atcaggtgct ggaaaccgct
    12841 aatcgcctgc gagaaaacgg taaagaggca gaagcggaag cgctgctgcg ccagcaaccg
    12901 ccttcctcgc gtattgacct cacgctggct gactgggcgc agcagcgacg tgattacacc
    12961 gccgcccgcg cggcttatca gaacgttttg acgcgcgagc ccactaacgc cgatgccatt
    13021 cttggtctga cggaagtgga tattgctgcc ggtgacaaag cggcggcacg tagccagctg
    13081 gcgaaactgc ctgccactga taacgcctcg ctgaacacac agcggcgcgt ggcgctggca
    13141 caggcgcagc ttggcgatac cgcagcggcg cagcagacat ttaataagtt gatcccgcag
    13201 gcaaaatctc agccaccgtc gatggaaagc gcgatggtac tgcgtgatgg tgcgaagttt
    13261 gaagcgcagg cgggcgatcc aatgcaggcg ctggaaacct acaaagacgc catggttgca
    13321 tccggtgtga ccacgacgcg tccgcaggat aacgacacct ttacccggct gacccgtaac
    13381 gacgagaaag atgactggct gaaacgcggc gtgcgcagcg atgcggcgga cctctatcgc
    13441 cagcaggatc ttaacgtcac tctcgagcac gattactggg gttcgagcgg caccggtggt
    13501 tactccgatc tgaaagcgca caccactatg ttgcaggtgg acgcgcccta ttctgacggg
    13561 cggatgttct ttcgcagtga tttcgtcaat atgaacgtcg gcagtttctc cactaatgcc
    13621 gatggcaaat gggatgacaa ctggggcacc tgtacattac aggactgtag cggcaaccgc
    13681 agccagtcgg attccggtgc cagcgtggcg gtcggctggc gaaatgacgt ctggagctgg
    13741 gatatcggta ccacgccgat gggcttcaac gtggtggatg tggtcggcgg catcagttac
    13801 agcgatgata tcgggccgct gggttacacc gttaacgccc accgtcggcc tatctccagt
    13861 tctttgctgg cctttggtgg gcaaaaagac tctccgagca ataccgggaa aaaatggggc
    13921 ggcgtgcgtg ccgacggcgt ggggctaagt ctgagctacg ataaaggtga agcaaacggc
    13981 gtctgggcat cgcttagcgg tgatcagtta accggtaaaa atgtcgaaga taactggcgc
    14041 gtgcgctgga tgacgggcta ttactataag gtcatcaacc agaacaatcg ccgcgtcaca
    14101 atcggcctga acaacatgat ctggcattac gacaaagacc tgagtggcta ctcactcggt
    14161 cagggcggtt actacagtcc gcaggaatac ctgtcgtttg ccataccggt gatgtggcgg
    14221 gagcgcacgg aaaactggtc gtgggagctg ggggcgtctg gctcgtggtc gcattcacgc
    14281 accaaaacca tgccgcgtta tccgctgatg aatctgatcc cgaccgactg gcaggaagaa
    14341 gctgcgcggc aatccaacga tggcggcagc agtcagggct ttggctacac ggcgcgggca
    14401 ttacttgaac gacgtgttac ttccaactgg tttgtcggca cggcaattga tatccagcag
    14461 gcaaaagatt acgcacccag ccatttcctg ctctacgtac gttattccgc cgccggatgg
    14521 cagggtgaca tggatttacc accgcagccg ctgatacctt acgccgactg gtaagttttc
    14581 agatagcgcc tctcttaatg ccgctgcgat cgggtatact cgggcggcaa tctgggattt
    14641 ccggggggag acaatttgcg cgtaagtcgc tcgttaacaa tcaagcagat ggcaatggtg
    14701 gcagccgttg tcctggtgtt cgtttttatt ttttgcaccg ttttgctgtt ccatctggtc
    14761 cagcagaatc gctataacac ggctacgcaa ctggaaagca ttgctcgctc tgtccgcgaa
    14821 cccttatctt ctgccatttt gaaaggcgat attcccgaag cggaagctat tcttgccagc
    14881 attaaaccgg caggcgtggt cagccgtgcc gatgtagtgc tgcccaacca gttccaggcg
    14941 ctgcgtaaaa gttttattcc agagcgtccg gtgccggtaa tggttactcg cctgtttgag
    15001 ctaccggtgc aaatctcgct gggcgtttac tcgctggaac gtccggcaaa cccgcagcca
    15061 attgcctatc tggtgctaca ggcggattcc ttccgcatgt ataagttcgt gatgagcacc
    15121 ctctcaacgt tagtgaccat ttacttactt ttgtcgttaa tattgactgt ggcgattagc
    15181 tggtgcatta accgcctgat tttgcatcca ttacgcaata ttgctcgcga acttaacgcc
    15241 atcccacccc aggatcttgt tggtcaccaa ctggcattac cgcgtctgca tcaggacgat
    15301 gaaatcggta tgttggtgcg cagttacaac ctcaaccagc aattgctgca gcgccattat
    15361 gaagaacaga acgaaaatgc gatgcgcttc ccggtgtcgg atttgccgaa caaagccttg
    15421 ctgatggaga tgctggagca ggtggtggcg cgtaaacaaa ccaccgcgct gatgatcatc
    15481 acctgtgaaa ccctgcgtga tactgcgggt gtgctgaaag aggcgcaacg agaaattctg
    15541 ctgctgacgc tggtggaaaa actcaaatcg gtactgtcgc cacgcatgat cctcgcgcag
    15601 attagcggtt atgactttgc tgtcattgcc aacggtgtac aggaaccgtg gcacgctatc
    15661 acattaggtc agcaagtgct cactatcatg agcgagcgcc tgccgattga acgtattcaa
    15721 ctccgtccgc actgtagcat tggcgtggcg atgttctacg gcgatctcac cgccgaacag
    15781 ctttacagtc gcgctatttc tgcggcattt accgctcgcc ataaaggcaa aaatcagatt
    15841 cagttctttg atccgcagca gatggaagcc gcccagaagc ggttgacgga agagagcgat
    15901 atccttaatg cactggaaaa tcatcagttt gcgatttggt tacagccaca ggtcgagatg
    15961 accagcggta aactggtcag tgcggaagtg ttactgcgta tccagcaacc ggatggcagt
    16021 tgggacctgc cggatggctt aatcgatcgc attgagtgct gtgggctgat ggttaccgtc
    16081 ggtcactggg tgctggaaga gtcctgtcga ttgcttgctg cctggcaaga gcgcggcatt
    16141 atgctgccct tgtcggtaaa cctctcagcg ctgcaactga tgcatccaaa tatggtggcg
    16201 gatatgctgg aactgttaac ccgctatcgc attcagccgg gaacactgat tctggaagtg
    16261 acagaaagcc gacgtattga cgatcctcat gctgcggtgg caatcctccg tccgctgcgc
    16321 aatgccggag ttcgggtggc gctggatgat ttcggcatgg gctacgcagg gctgcgtcag
    16381 ctgcagcata tgaaatcgtt gccaatcgac gtactgaaaa tcgacaaaat gtttgttgaa
    16441 ggtttgccgg aagatagcag catgattgct gcaattatca tgctggcgca gagcctgaac
    16501 ctacaaatga ttgccgaagg cgtggagact gaagcacaac gcgactggct ggcaaaagcg
    16561 ggcgttggta ttgcccaggg cttccttttt gctcgcccac tccctattga aatcttcgaa
    16621 gagagttacc tggaagaaaa atagctaccc caaactgatt acaaaacttt aaaaagtgct
    16681 ggtttgtgcg agccagctca aactttttaa cctttttgtt tcaattatga tccaggtaca
    16741 tttctgtgat gttgtctggg tgttatttta aggccgcagg taccccataa ccttacaaga
    16801 cctgtggttt tactaaagga caccctatga aaacctctct gtttaaaagc ctttactttc
    16861 aggtcctgac agcgatagcc attggtattc tccttggcca tttctatcct gaaataggcg
    16921 agcaaatgaa accgcttggc gacggcttcg ttaagctcat taagatgatc atcgctcctg
    16981 tcatcttctg taccgtcgta acgggcattg cgggcatgga aagcatgaag gcggtcggtc
    17041 gtaccggcgc agtcgcactg ctttactttg aaattgtcag taccatcgcg ctgattattg
    17101 gtcttatcat cgttaacgtc gtgcagcctg gtgccggaat gaacgtcgat ccggcaacgc
    17161 ttgatgcgaa agcggtagcg gtttacgccg atcaggcgaa agaccagggc attgtcgcct
    17221 tcattatgga tgtcatcccg gcgagcgtca ttggcgcatt tgctagcggt aacattctgc
    17281 aggtactgct gtttgccgta ctgtttggtt ttgcgctcca ccgtctgggc agcaaaggcc
    17341 aactgatttt taacgtgatc gaaagtttct cgcaggtcat tttcggcatc atcaatatga
    17401 tcatgcgtct ggcacctatt ggtgcgttcg gggcaatggc gtttaccatc ggtaaatacg
    17461 gcgtcggcac actggtgcaa ctgggacagc tgattatctg tttctacatc acctgtatcc
    17521 tgtttgtggt gctggtattg ggttcaatcg ctaaagcgac tggtttcagt atcttcaaat
    17581 ttatccgtta catccgtgaa gaactgctga ttgtactggg gacttcatct tccgagtcgg
    17641 cgctgccgcg tatgctcgac aagatggaga aactcggctg ccgcaaatcg gtggtggggc
    17701 tggtcatccc gacaggctac tcgtttaatc ttgatggcac atcgatatac ctgacaatgg
    17761 cggcggtgtt tatcgcccag gccactaaca gtcagatgga tatcgtccac caaatcacgc
    17821 tgttaatcgt gttgctgctt tcttctaaag gggcggcagg ggtaacgggt agtggtttta
    17881 tcgtgctggc agcgacgctc tctgcggtgg gccatttgcc ggtagcgggt ctggcgctga
    17941 tcctcggtat cgaccgcttt atgtcagaag ctcgtgcgct gactaacctg gtcggtaacg
    18001 gcgtagcgac cattgtcgtt gctaagtggg tgaaagaact ggaccacaaa aaactggacg
    18061 atgtgctgaa taatcgtgcg ccggatggca aaacgcacga attatcctct taatctcacc
    18121 acttatgccc gcactccctt ccccgagtgc gggtgtttgc gcataattga cccctgtgcc
    18181 tgaacttacc acctgggtga gttcaggttt atttcacttc ttccgtgaca ttttcatgtt
    18241 cttgcggtct aacacgaagt gtttttaacg tcatttagac tgaccgacaa cgggcagttt
    18301 tttattacca ggatagttga tcaggggttc acatgcaggg cacaaaaatt cgacttttag
    18361 cgggcggttt gctgatgatg gccactgctg gctatgtgca ggcagatgcg ctccagcctg
    18421 atccagcatg gcaacagggg acgctttcca acggtttaca gtggcaagtg ctgactacac
    18481 cccagcgtcc cagcgatcgt gttgaaattc gcctgctggt taataccggt tcgctcgccg
    18541 aaagtacaca acagagcggt tacagtcacg ccatccctcg tattgcgcta acgcaaagcg
    18601 gtggccttga cgcagcgcag gcgcgttcat tgtggcagca ggggatcgac cctaaacgcc
    18661 cgatgccgcc ggtaattgtc tcttatgaca ccacgctgtt taatctgagt ttgcccaata
    18721 accgtaacga cttgctgaaa gaggcgctct cttatctggc aaatgccact ggcaaactga
    18781 ctatcacgcc agaaaccatc aaccatgcgt tgcaaagtca ggacatggtg gcaacctggc
    18841 ctgccgatac taaagagggc tggtggcgtt atcgtctgaa aggatcaacc ttgttaggtc
    18901 acgatcctgc cgatccgctg aaacaacccg ttgaagcgga aaagattaaa gatttctatc
    18961 agaaatggta caccccggat gcaatgacgc tgctggtggt gggaaacgtg gatgcgcgct
    19021 cggtcgtcga ccaaatcaat aaaacgtttg gcgaactgaa aggcaaacgt gaaacaccgg
    19081 ctccggtgcc gacgctttct ccgctgcgtg cggaagcggt gagtattatg accgacgcgg
    19141 tgcgtcagga ccggttatct atcatgtggg atacgccgtg gcagccgatt cgtgaatcag
    19201 ccgcactgct gcgctactgg cgtgcggacc tggcccgtga ggcgctgttc tggcatgttc
    19261 agcaagcgtt aagcgccagt aacagtaaag acatcggtct tggatttgac tgtcgtgtgc
    19321 tgtatctgcg tgcgcagtgt gccatcaaca tcgaatcacc aaacgacaag ctgaacagca
    19381 accttaatct ggtggcgcgt gaactggcga aggttcgcga taaaggtctg ccggaagaag
    19441 agttcaatgc gttagtggcg caaaagaaac tggagctgca gaagctgttt gccgcctatg
    19501 cgcgagctga taccgatatt ctgatggggc agcggatgcg ttcgttgcaa aatcaggttg
    19561 tcgatatcgc gccggagcaa tatcagaaac tgcgtcagga tttccttaac agcctgacgg
    19621 tggagatgtt aaatcaggat ctgcgtcagc agttgtcgaa tgatatggcg ttaatactgc
    19681 tgcagccgaa aggcgagccg gaatttaaca tgaaagcgtt gcaggcggcc tgggatcaaa
    19741 tcatggcccc atcgactgcg gctgccgcca catctgtcgc cacggatgac gtacatcctg
    19801 aagtgacgga tattccacct gcacagtaat gcctgatggt gatgagttag cacaaccatc
    19861 aggtatttat ggatgagctg gatagggggg taacactcta tccagccttt tgcatatgct
    19921 gcttttacgc tggcatcgct tcacgcggga taatcgcgcc gcgatactga ataacggtac
    19981 ttgcggtcag gtgcccgcgt ttcgctgcgt cttccgcact gccgcccgtc aaacgtaccg
    20041 ccagataacc ggcactgaaa gagtcgccag ctgcggtggt atcgatcact ttttctttcg
    20101 gcagttttac cgccggaaca tccactaacc cttcaccagc aatggacacc aggcaagaat
    20161 ccgccccgcg tttcaccacc acttctttca cgcccgcgtt atgggtgcgc gcaatgacgt
    20221 cttccaccgg ctgttgaccc cacagcgcgt cttcatcgtc cagcgtcagg aaggcgatat
    20281 ccgtgcattc cagcatttgt tggtacacct gctgtgtctc ttctttgctg gcccacaggc
    20341 gcggacgata gttattgtcg aaaatcactt ttccgccgtt ggcgcggcat tcgcgcagca
    20401 gggaaagcag cttttcgcgg ctggtcgggc ttaagatcgc caggctaatc ccgctcaggt
    20461 agagataatc gaaattcgcc agctcttcgc aaatcgtcgc ggattgctca ctctccagcc
    20521 agaatttggc ggcggcttcg ttacgccagt agtagaacgt acgttcgccg gtgctgtcgg
    20581 tttcaatgta gtaaaggccc ggcagacggt tttccatccg ttgggtcagg gaagtatcaa
    20641 cgttctcgcc gcgccaggcg tccagcatct gctggctaaa actgtccgtt cccagcgccg
    20701 ttacgtaatg aacggttaat gccgcaggat cgacctgacg ggcgatatag acggaagtgt
    20761 tcagggtatc gcccccgaaa ccgcgcttaa cgtccgcgcc tttctcggaa agctcaatca
    20821 tgcattcgcc aatcacggca atctttttgg acatagttgt gaacctgatc tgtaaaaaat
    20881 tagcgttagt ttgcgctgtg gtggtttgct ggtcaaccat attaaaacag tgttccatta
    20941 tttttttgag ccagaacgta ttcctgaaag attccgttgt ggagtgggga aatttacccc
    21001 ggccaggcgg taaagttctg cctttgcgcg ccgataatct ttgtcgagtc cgggcagcat
    21061 cacttttaaa cacaggacat ctttgatgat aaggcaggtt atccagcgaa taagcaaccc
    21121 tgaagcaagc atcgagagct tgcaggaacg gcgtttttgg ttgcagtgtg agcgtgctta
    21181 cacctggcag ccgatctatc aaacatgcgg gcggttaatg gccgtggagc tattaacggt
    21241 ggtcacgcat cccttgaacc cttcgcaacg cctgccgccg gatcgctatt ttactgaaat
    21301 caccgttagc catcggatgg aggttgtgaa agagcagatt gatttgctgg cgcaaaaagc
    21361 cgacttcttt gtagagcacg gcctgctggc atcggtcaat attgatggcc ctacgctcat
    21421 cgccctgcgt cagcaaccaa aaatcctgcg ccagattgag gagcttccct ggctgcgttt
    21481 cgaactggtg gaacacatcc gcctgccgaa agattcaacc tttgcctcga tgtgtgaatt
    21541 tggcccgctg tggctggatg attttggtac cgggatggca aatttctctg cactaagtga
    21601 agtgcgttat gactacatca aaatcgcgcg agaactgttt gtgatgctgc gtcagtcacc
    21661 ggaaggacgc acactctttt ctcagctttt acatctaatg aatcgctatt gtcgcggggt
    21721 gattgtcgag ggcgtagaaa caccagaaga gtggcgtgat gttcagaact cgcccgcatt
    21781 cgccgcacaa ggctggtttc tttcacgccc ggcaccgata gaaacgctga atacggcggt
    21841 tctggcgcta taagctgcct cattttccgc ctggctggac tatctttagg actggcacag
    21901 aaagaatatg aggaagcgaa cgatgagcaa ggcaggcaaa ataaccgctg cgatttcagg
    21961 ggctttcttg ttgttgattg tcgtggcgat cattttgatt gcaacttttg actggaatcg
    22021 actcaaaccg accatcaacc agaaagtctc tgcggagttg aatcgtccgt tcgctatccg
    22081 tggcgatctg ggcgtggtgt gggagcggca aaaacaagaa actggctggc gcagctgggt
    22141 gccgtggccc catgtacacg cggaagacat cattcttggc aatccaccgg atattcccga
    22201 agtcacaatg gtgcatttgc cgcgagtaga agcgacgctg gccccgctgg cgctgctgac
    22261 caaaacggtc tggttgccgt ggatcaagct cgaaaagccc gacgcgcgcc tgattcgcct
    22321 ctccgaaaag aacaataact ggacgtttaa tctcgccaac gatgacaaca aagacgcgaa
    22381 tgcaaagccg tcggcgtggt cgtttcggct ggataatatt ctgttcgatc aagggcggat
    22441 cgccattgat gacaaagtaa gcaaagcgga tctggaaatt tttgtcgatc cgttaggcaa
    22501 gccgctgtcg ttcagcgaag ttaccggatc gaaaggtaaa gcggataaag aaaaggtggg
    22561 cgattacgtt tttggcctga aggcgcaggg acgttataac ggtgaaccgc tcactggtac
    22621 gggaaaaata ggcggtatgc tggcgctgcg tggcgaagga acgccgtttc cggtacaggc
    22681 tgatttccgc tctggtaaca cccgtgttgc ttttgatggc gttgtgaatg acccaatgaa
    22741 gatggggggt gtcgatttac ggcttaaatt ttctggcgat tcgctgggtg atctctatga
    22801 actgacgggc gttctgctgc ccgatacacc gccgtttgaa acggatggtc ggctggtagc
    22861 gaaaatcgat actgaaaaat cgtcggtctt tgattatcgc ggttttaatg ggcgcattgg
    22921 cgatagcgat atccacggtt ctctgatcta caccaccggc aagccacgac caaaactgga
    22981 aggtgatgtc gagtcgcggc aattgcggct ggcggacctg ggaccgttga ttggcgttga
    23041 ttccgggaaa ggggcagaaa agtcgaaacg gtctgaacag aagaagggcg aaaaaagcgt
    23101 tcagcctgcg ggcaaagtgc tgccttatga ccgcttcgaa accgataaat gggacgttat
    23161 ggatgccgat gttcgcttca aagggcggcg cattgagcat ggcagcagcc tgccgattag
    23221 cgatctttct actcatatca tcctcaaaaa tgctgacctg cgcctgcaac cgctgaaatt
    23281 tggcatagcg ggcggcagca ttgcggcgaa tattcatctg gaaggcgata aaaagccgat
    23341 gcaggggcgg gcagatattc aggctcgtcg actgaaactg aaagaactga tgcccgatgt
    23401 agaactgatg cagaagacgc tgggggaaat gaacggtgac gcggaactgc gcggtagcgg
    23461 taactcggtg gcggcgcttt taggcaacag taacggcaac ctgaaactgt tgatgaatga
    23521 cgggctggtg agccgcaacc tgatggagat tgttgggctg aatgtcggca actacattgt
    23581 cggtgcgata tttggtgatg atgaggtgcg ggtgaactgc gcggcggcga atctggatat
    23641 tgccaacggc gtggcgcgcc cgcagatttt tgctttcgat actgagaacg cgttgattaa
    23701 cgttaccggt acggcaagtt ttgcttcgga acagctggat ttgactattg atccggagag
    23761 taaagggatt cggattatca cattgcgttc gccgctgtat gtacgtggga cgtttaaaaa
    23821 tccgcaggct ggggtgaaag ccgggccgtt gattgctcgc ggagccgttg cggcggcact
    23881 ggcaacgctg gtaacaccgg cggcggcgtt actggcgctg atctcacctt ccgaagggga
    23941 ggctaatcag tgcaggacaa ttttgtcgca gatgaagaag tgatgataat tgccggatgt
    24001 ctgacatccg gcaattaaac agatttagat tgttggcaaa gtgtgctttg ttcatgccgg
    24061 atgcggcgtg aacgcctccg gcttacaaat ccttgcgaat tcaatatatt gtatggaaat
    24121 tctggcctga taagcgtagc gcatcaggct tttcactctt attacaacga ctgatgtcgc
    24181 gtctcatggg tcagcagcag ggcgattaac gtcaagccag ccatcgccgc cagatatagc
    24241 cccaccgcac ctaacccgta gttagtctgc aaccaggctg cgatatacgg cgcaacggaa
    24301 gccccgagaa tcgacgatac gttgtaagag aacgatgctc cggtgtaacg cacttctgtc
    24361 gggaacagct ctggtaacag cgcgcccatc ggaccgaagg tcagccccat cagacttaac
    24421 cccagcagca gaaaggcaaa aaccagaatc gggttgccag aaccgagcaa aggggtaaag
    24481 gcgaatagcg cgaacaggat gatcagcgtg gtgatgatca ccatgctttt acggcgacca
    24541 aaggcatcag ccagtaatcc ggcgactggc accatcacgc caaaaccaat aactgccatc
    24601 atcagcatcc acaacacttc gttacgcggc aggccaagcc caactggcgc ggcggcggta
    24661 ctaaaggtca tagagtagac cgtcatgatg taaaacagcg tataggttgc cagcataatg
    24721 aacgtaccca gtacggttac gcgaacatgt ttggtcagca gcgtacccag cgggatcttc
    24781 acctgttttt tcgctttagc gactttctca aacaccggcg actcatgcag cgacacgcga
    24841 acatacaggc cgataatgac cagcaccgcc gagaagataa atggcacacg ccagccccag
    24901 ctcataaact gctcgtcggt cagtagccag gaaagcagca agaaagtgcc gttggcaaag
    24961 aagaagccaa tcggtgcgcc cagctgcggg aaggagccgt acaatgcacg tttgcgcggt
    25021 ggggcgtttt cagtcgccag cagcgccgcg ccgccccatt caccacctaa gcccagaccc
    25081 tgaccaaatc gagccagcgc cagcagcagc ggggcgaaaa taccaatcgt ggcatagcct
    25141 ggcagcagac caatcaccac ggtcgaaatc cccatcgtta gcaacgaggc gaccagcgtc
    25201 gctttacgcc caacgcgatc gccaaaatga ccaaaaacgg cagagccaat ggggcgcgcg
    25261 acgaaggcga tggcgaaggt ggcgagcgac tgtagcgttg ctgccgttgg atcgccctgc
    25321 gggaagaaga tatgcggaaa cacaataacg gccgcagtgg cgtaaatgta aaagtcgaag
    25381 aactcaatgg ccgtgccaat gagagaggcg acaaggactt tattacgcga gttgatcggc
    25441 gtgtattctt gctcgtggtc gagtgttgtg gctgttgctt gcataatctt ttcttatttt
    25501 ttggctaacg aatagccata ttacgcacag caaaagtgat atttcaatgt gtaacaaatc
    25561 gcggaaatgg tcaaaaatca ggcaaaaagg gaataatgtt taggccagtg atttttcttc
    25621 tatgaaatgc ttcacataat tttataaatg gtggattaaa ctggttttag gttaaataaa
    25681 agttaccaac tggatttata tgctggggtt atgagttgga atgaaattgt ttgctcctga
    25741 atagatggct aaagaggctc tgggaaagag tttcaagagg ttatgtgcgc attatagccg
    25801 gatgcgatgc tggcgcatct tatccggcct acggggagcc aggccggata aattcgtacg
    25861 ccgcatccgg cctattttaa ggctgtgttt tccccggcat tcgcgggtcg tctttatatt
    25921 cggcggtggc aatccacgcc gcgcaaaaca gcgtcaaacg ggcgaagaag tagaaaaatg
    25981 ccatcagccc cagcacggaa ccaaatgctg cgccagaggg tgatttcatc aacgatggca
    26041 gggtgtaggt catcacgatt ttaatcactt caaaaccaat agcagccaga aatgttccgc
    26101 ggatcagggc ttttttgcgc ggacggtggc gcggcaaccg ccagaagatc cagaagaaaa
    26161 gcagatagtt ggcgaagatg gaaatcgcca cgccaatcaa ccgccatgtc ggtttcagcc
    26221 actcaatgct gttcaggtgc agggcgctaa taatcatttg ctgcgcagaa ccggcaaccg
    26281 aggtgataga aagcgtcaca atcagcgcaa tcaacaaacc aatcagcgaa ataaaatcac
    26341 gcagatattt tacccagaac ttctcctgat cttgcggcga gcgttcccag acatcgcgtg
    26401 actgggcgcg aatcgcttca cgcaggttac ccatccagtt gatgccggaa taaagtgcca
    26461 ctgccagacc gacaagccct acagtcgtac gctgctgaac ggcggtgttg atggtgtttt
    26521 tcaatgtggc ggctagcgtc ggatcgctga tgttttgcag aattttgtcg aagatatcct
    26581 gtagcaacat cggatgggag gcgagcacaa agccccctgc ggcaaacgac accatcaaaa
    26641 tggggatcat cgacaaaaat gagaaatagg tgatagccgc accaaactgg ttacccagcc
    26701 gatcgttaaa gcgttctgtc gcgcgaatca ggtgcgcaat aaccggttgg cgttggactt
    26761 tctcggcagt ggtggtgacg gtttccagcg cctggctaac tttgccgcct ttctcgctat
    26821 tatccaactg cttaatcggc tcgtgctcca gatcctgggt gggacgtttg atctcgtttt
    26881 cctgcgtcat ccgctctttt gtccttctgt cgtggtcatt cttaaaagta tagtcggtca
    26941 gtccaggtac tctttcatta cgccagccag ccactgcata aacaggttta cacgccggga
    27001 aagctcccga cgctgcggat aaaccagtga aagggacagc ggctcggcac ggtagccagg
    27061 caacacttca ataagccgcc cggcacgcag ggcttcgcgc acggcaatgc gcgggatctg
    27121 aataatcccc agaccggcaa gaccggcggc gagatagttt tcgctactgt ttaccgtcaa
    27181 catgctgcca gacttaaacc actggacgcc attaacgctg gcaacctcaa aacctaacgg
    27241 atgtacaccc aggtgcggtg tataacgcac tattgcgtgt gaagtcagat catcggggct
    27301 ttgcggataa ccaaagcgcg tcagatagtg cggactggca cagttgacca tggtcagttt
    27361 accgagggga cgggcgataa cgccatcttc cggtaatgcg ccagtgcgta tcacgcaatc
    27421 aaaaccatca tgaagaatat ctaccggacg gtcatggcta ctcagttcca gctcaattcc
    27481 cggatgcaga tagagaaatt ccgacaagcg cggcagtaac aggcttttcg cgattcctga
    27541 cgggatgtcg atgcgtaatt taccgctgat actggtggca tcctgttgaa acagaccgtc
    27601 cagttcgctg agattactca acacatcttt tgctcgttga taataggtca tgccttctgg
    27661 cgtgagtttg acccgtcgcg tggtgcgctg gagaagctgg gtgccaagtt gatgttccag
    27721 tgcctgtatc tggcgcgaaa cacttccctt tggcaaagca aagaaatccg ccgcgcggga
    27781 aaaactttcc agctccgcga ctttgatgaa caactgcatt gcgtgaattt tatccatttc
    27841 tttgaccgat tgttgttcac aacgaaacag tagcgtgcat atcgcattgt ttattgtttt
    27901 ttctaacatc taatgccggg tttcacaatg ttgtcatgat gaatgtggcg atttctcagc
    27961 aggaaaaggg aggaatagct ttatgagaaa ggtaaattcc cttaaacaga gcgtattttt
    28021 cagcgattcc ctttaaagtg aatagaagat gtattggcta tttgtgctta tttttatctc
    28081 attgccgttt gttatttttg tttatggtcg cggaatttca tttttaattg catgcgtact
    28141 aactaccgat ataaggaaat cctcaaaaat gttttaaata gtgccctcga catgtaattt
    28201 caggcgttta gctgtaacta tttatatcgg taactatttt ctacgtgtca tctctgtaga
    28261 atggccaccg ccaaatggcg aattcttatt ttttctcgcg ggtaataccc ttccactact
    28321 taagtctttt taacgtattc aggtggagat tcagttatgc aaatagtcat gtttgacagg
    28381 cagtcaatat ttattcatgg aatgaaaatc agtttacagc atcgtattcc aggagtgagt
    28441 attcaggggg ccagtcaggc agacgagtta tggcaaaagc tggaaagtta ccctgaagcc
    28501 ttagtgatgc tcgatggcga tcaggatggt gagttttgct actggttgct gcaaaaaact
    28561 gtggtgcaat ttcctgaggt taaggtgtta attacggcga cggattgcaa caaacggtgg
    28621 ttacaggaag ttattcattt taatgtgctg gccattgtgc ctcgtgattc aaccgtcgag
    28681 acatttgcgt tggcggtaaa tagtgcggcg atggggatga tgtttctgcc tggagactgg
    28741 cgaacgacgc cggaaaagga cattaaagat ctcaaatcgt taagcgcccg ccagcgggag
    28801 attttaacca tgttagcggc gggcgaatca aataaagaga tcggcagggc gctgaatatc
    28861 agtaccggaa cggtaaaagc gcatctggaa tcactgtatc gccgtctgga agtcaaaaat
    28921 cgcacccagg cggcaatgat gttaaatatc tcctcctgaa gaggataatt ttacagccag
    28981 caggaagtta gcggctggct gtaaaaatat tatggttcgc cgtacaaacc aattaaacgg
    29041 cgtaccacac cgttagtcca gccaaaccca tcctgcaacg gatactcgcc accgccgcct
    29101 tcgcgaggaa caccatcggc aatatggtat ttctcgatca gtttgtgctg ttccagatag
    29161 aactgattca ccgtcttcag ccagttgcgc gcgatttcat cacccagaag gtcatcgccg
    29221 tacatcttaa atccctgaat tgccatccac tgtaacggtg cccagccgtt gggtttatcc
    29281 cactgttcac cggtttcgta ctcgcttgcc agaatcccgc caggtgtcag taaccggctg
    29341 cgcacggcgt ttgccagacg atcggcctgt tcatggttcg ccataccgac atagagcggc
    29401 acaatggcgg cagcggaaaa cagcgccagt tgctcgcgtc gccagtcgta atcgcggtag
    29461 ataccgtttt catcatccca gaggtaacgg tttaccgcat cgcgacgggc actggccttc
    29521 tggcggaaca gtgcttctgt ctctttctcg cctttcagtg ccgagatgtt ggcgatggcg
    29581 ctctccagtt taaacaggaa ggcattcaga tcgatgggga tgaactgggt ggtacgaatg
    29641 ctcgccagac gaccagtatc acgcagccaa cgggaagagt aatcccaacc ggaggccgcc
    29701 cccgcacgta aatcgcggta cacctcgtta ggcgggcgac cagaatgttt cgcggtttca
    29761 acgtcctcaa gccaggattc gtcacgcggc gtgtcgcgat cgtcccagta acggttgagc
    29821 agcgagccgt ccggcatccg cacaacatgg cgataggcct gattagggat caacgattct
    29881 gcaccgtcca tccagaaggc atattccatt ttcaggtggt cgagatagcg gcgcgcgccg
    29941 cgtacaccat cttcttcaaa caactccacc atcagcgcaa aaaccggtgg ttgcgagcgg
    30001 ctcaaataat aggtgcggtt gccgttgggg atgtggccgt agttttcgat catccaggcg
    30061 aagttatcgg ccatgcattt cagcaaatct tcccgaccac tttccgccag ccccagcatg
    30121 gtgaaatagg aatcccaata gtaggtttcg ctaaaacggc cgcccgggac aatatatgac
    30181 tgcggcagcg ccagcagaga agaccacgga atgtgatcct gtggttcacg ggttagcacc
    30241 ggccacagct ggtcgatatg ctctttcagg gaattttgcg ggtccgatac atactcgctg
    30301 gagtagacct ccggcagcca gaagtggttt tcaacaaact tgcgcaagtc aaaatcacga
    30361 tgacggcgca ctttacggta gcggattaaa atatccagcg ggtccatttt gggtgcgcag
    30421 tcgggaaagg ttttactgtc ggggaaaatt ttcgccgact gaacatgctc gaacagttcg
    30481 agatagcgat cggcaggcgt cagcgcatca gaggcgggca gcccttcaat catctcgggt
    30541 tccggttctg cctcgatcat ctcatccagt tttaattcat acgggtccag ctcatagcag
    30601 agatcgacct cgatcatcag ttcgtctgga ttagggtttt gaattttctg attgagcata
    30661 aggatccgac ctccgaaatt cgtcgctaat tatcgggctt ttctttaagg gtagtcattc
    30721 gctccgcctg gtgggcgaca aagcgtgcgg tggatcacgt ttattaacct gccaaaaaat
    30781 ataacgcact aatatcaatg gaatttataa aaatacggat ttcgtgttgt ttttcatttt
    30841 cagaacattc aatcctgctc tcgccgcaat catgatatgc cattcctgat ctgggtaata
    30901 ggcactggct atcttattga tagtttatat tcatgtaatt gattgattcc tatcaaaaag
    30961 catatctccc tgttttttat gatggctttg tctcgcagag acgtttgcag cattctggaa
    31021 aattttctgg gtcacaataa ctcactaccg tgagggaaga ataatgaaaa tggtctcacg
    31081 tattaccgcg atcggcctgg ctggcgtcgc gatttgctat ttagggttat ctggttatgt
    31141 gtggtaccac gataataaac gcagtaaaca ggccgatgtt caggcatctg ctgtcagtga
    31201 aaataataag gttttaggct ttctccgcga aaaaggatgc gattattgcc atacgccttc
    31261 ggcagaatta cccgcctatt attatattcc cggcgcgaaa cagttgatgg attacgacat
    31321 aaagcttgga tataaatctt ttaacctcga ggccgtgcgt gcggctctgc tggctaataa
    31381 acccgtttcg caaagcgatc tgaataagat tgaatgggtg atgcagtatg aaactatgcc
    31441 gccaacgcgt tataccgcgc tacactgggc gggtaaggtg agtgatgaag agcgggcgga
    31501 aatactggcc tggattgcaa aacagcgcgc ggaatattac gccagcaatg atactgctcc
    31561 ggagcatcgc aatgaaccgg tgcagcccat cccgcaaaaa ctgcctaccg atgcgcaaaa
    31621 agtggcgttg ggttttgcgc tgtatcacga tccccgttta tcggcggata gcaccatttc
    31681 atgcgctcat tgccatgcgt tgaatgcggg gggcgtcgat ggcagaaaaa catcgattgg
    31741 tgttggtggc gcagttgggc cgattaacgc gccgacggta tttaactcag tatttaacgt
    31801 tgagcagttc tgggatggtc gtgcggcaac attgcaggat caggctggtg gaccgccgtt
    31861 gaacccgatt gaaatggcgt cgaaatcctg ggacgaaatt attgctaagc tggaaaaaga
    31921 tccgcagctt aaagcgcagt tcctcgaagt ctatccgcaa ggtttcagtg gcgaaaatat
    31981 tactgatgcc attgctgaat ttgagaaaac attaattacg ccggattccc catttgataa
    32041 atggttgcgt ggagatgaga atgctctgac ggcgcaacag aaaaaaggct atcaattatt
    32101 taaagataat aaatgtgcaa cttgtcatgg tggtattatt ctcggcggac gttcctttga
    32161 accgttgggg ctgaaaaaag actttaactt tggtgaaatt acggcggcgg atattggtcg
    32221 tatgaatgtt actaaagaag agcgtgataa attgcgtcag aaagtacccg gtttacgtaa
    32281 cgttgcttta acggcaccgt acttccatcg cggtgacgtg ccgacgctgg acggggcagt
    32341 gaaactgatg ctgcgctatc aggtaggcaa agagctgccg caggaggatg tggatgatat
    32401 cgtagctttc ctgcacagtc tgaacggggt ttacatgccg tatatgcagg ataaaca
//
LOCUS       DAPOXO010000062        30509 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPOXO010000062 DAPOXO010000000
VERSION     DAPOXO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30509
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.062"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..864
                     /gene="tuf"
                     /locus_tag="ROH59_003239"
     CDS             <1..864
                     /gene="tuf"
                     /locus_tag="ROH59_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDX4805684.1"
                     /translation="ATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVE
                     MEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDK
                     PFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLD
                     EGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFK
                     GYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRT
                     VGAGVVAKVLS"
     gene            1094..1477
                     /gene="secE"
                     /locus_tag="ROH59_003240"
     CDS             1094..1477
                     /gene="secE"
                     /locus_tag="ROH59_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDX4805685.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            1479..2024
                     /gene="nusG"
                     /locus_tag="ROH59_003241"
     CDS             1479..2024
                     /gene="nusG"
                     /locus_tag="ROH59_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDX4805686.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            2183..2611
                     /gene="rplK"
                     /locus_tag="ROH59_003242"
     CDS             2183..2611
                     /gene="rplK"
                     /locus_tag="ROH59_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDX4805687.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            2615..3319
                     /gene="rplA"
                     /locus_tag="ROH59_003243"
     CDS             2615..3319
                     /gene="rplA"
                     /locus_tag="ROH59_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDX4805688.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAE
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     IRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            3611..4108
                     /gene="rplJ"
                     /locus_tag="ROH59_003244"
     CDS             3611..4108
                     /gene="rplJ"
                     /locus_tag="ROH59_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDX4805689.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            4175..4540
                     /gene="rplL"
                     /locus_tag="ROH59_003245"
     CDS             4175..4540
                     /gene="rplL"
                     /locus_tag="ROH59_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDX4805690.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4860..8888
                     /gene="rpoB"
                     /locus_tag="ROH59_003246"
     CDS             4860..8888
                     /gene="rpoB"
                     /locus_tag="ROH59_003246"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDX4805691.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8965..13188
                     /gene="rpoC"
                     /locus_tag="ROH59_003247"
     CDS             8965..13188
                     /gene="rpoC"
                     /locus_tag="ROH59_003247"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDX4805692.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYTIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            complement(13430..14563)
                     /gene="thiH"
                     /locus_tag="ROH59_003248"
     CDS             complement(13430..14563)
                     /gene="thiH"
                     /locus_tag="ROH59_003248"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDX4805693.1"
                     /translation="MKTFSDRWRQLDWDDIHLRINGKTAADVERALNASQLTRDDMMA
                     LLSPAASGYLEPLAQRAQRLTRQRFGNVVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAEAEYAELKQLGLDGVMVYQETYHEATYAHHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDSWRVDCYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQAICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGRPSQRP"
     gene            complement(14560..15330)
                     /gene="thiG"
                     /locus_tag="ROH59_003249"
     CDS             complement(14560..15330)
                     /gene="thiG"
                     /locus_tag="ROH59_003249"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDX4805694.1"
                     /translation="MLHIADKTFDSHLFTGTGKFASSQLMVESIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVALLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA"
     gene            complement(15332..15532)
                     /gene="thiS"
                     /locus_tag="ROH59_003250"
     CDS             complement(15332..15532)
                     /gene="thiS"
                     /locus_tag="ROH59_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDX4805695.1"
                     /translation="MQILFNDQPMQCVAELTVHELLEQLEQQQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(15516..16271)
                     /gene="thiF"
                     /locus_tag="ROH59_003251"
     CDS             complement(15516..16271)
                     /gene="thiF"
                     /locus_tag="ROH59_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418420.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HDX4805696.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIRLMA
                     LQQRLTGETLKDAVAQADVVLDCTDNMATRQEINATCVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLTLRRASGCPVCGGCNADPV"
     gene            complement(16264..16899)
                     /gene="thiE"
                     /locus_tag="ROH59_003252"
     CDS             complement(16264..16899)
                     /gene="thiE"
                     /locus_tag="ROH59_003252"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709787.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDX4805697.1"
                     /translation="MYQPEFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDQR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAG
                     LRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYP
                     TVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE"
     gene            complement(16899..18794)
                     /gene="thiC"
                     /locus_tag="ROH59_003253"
     CDS             complement(16899..18794)
                     /gene="thiC"
                     /locus_tag="ROH59_003253"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDX4805698.1"
                     /translation="MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARKGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(18875..18975)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(19027..19503)
                     /gene="rsd"
                     /locus_tag="ROH59_003254"
     CDS             complement(19027..19503)
                     /gene="rsd"
                     /locus_tag="ROH59_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HDX4805699.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDDYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA"
     gene            19598..20371
                     /gene="nudC"
                     /locus_tag="ROH59_003255"
     CDS             19598..20371
                     /gene="nudC"
                     /locus_tag="ROH59_003255"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HDX4805700.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            20411..21475
                     /gene="hemE"
                     /locus_tag="ROH59_003256"
     CDS             20411..21475
                     /gene="hemE"
                     /locus_tag="ROH59_003256"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HDX4805701.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVASILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSEQYHR"
     gene            21485..22156
                     /gene="nfi"
                     /locus_tag="ROH59_003257"
     CDS             21485..22156
                     /gene="nfi"
                     /locus_tag="ROH59_003257"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HDX4805702.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALEWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            22199..22789
                     /locus_tag="ROH59_003258"
     CDS             22199..22789
                     /locus_tag="ROH59_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HDX4805703.1"
                     /translation="MLQNPIHLRLERLASWQHVTFMACLCERMYPNYAVFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            22976..23248
                     /gene="hupA"
                     /locus_tag="ROH59_003259"
     CDS             22976..23248
                     /gene="hupA"
                     /locus_tag="ROH59_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HDX4805704.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            23261..23956
                     /locus_tag="ROH59_003260"
     CDS             23261..23956
                     /locus_tag="ROH59_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HDX4805705.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALFLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGQKQQLSNDQIDLYRYRAAQIREISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(23958..24377)
                     /gene="zraP"
                     /locus_tag="ROH59_003261"
     CDS             complement(23958..24377)
                     /gene="zraP"
                     /locus_tag="ROH59_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HDX4805706.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGTGMGYGGCGGGGHMGMGHW"
     gene            24615..25991
                     /gene="zraS"
                     /locus_tag="ROH59_003262"
     CDS             24615..25991
                     /gene="zraS"
                     /locus_tag="ROH59_003262"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HDX4805707.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAA
                     ARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEEMAGQPGVRWFAVTDEQGTI
                     VMHSNSGMVGKQLYSPQEMQQLHPGDEEAWRRIDSADGEPVLEIYRQFQPMFAAGMHR
                     MRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRY
                     LRSGQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQL
                     AQVMAKEADRLNRVVSELLELVKPTHLALQAVELNTLISHSLQLVSQDANSREIQLRF
                     TANDTLPEIQADPDRLTQVLLNLYLNAIQAIGLHGVISVTASESGAGVKISVTDSGKG
                     IAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVN
                     ITRKDPQG"
     gene            25988..27313
                     /gene="zraR"
                     /locus_tag="ROH59_003263"
     CDS             25988..27313
                     /gene="zraR"
                     /locus_tag="ROH59_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HDX4805708.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSIDAETPAVSASQFGMVGKSPAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQTISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIP
                     LVQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(27310..28599)
                     /gene="purD"
                     /locus_tag="ROH59_003264"
     CDS             complement(27310..28599)
                     /gene="purD"
                     /locus_tag="ROH59_003264"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDX4805709.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLDFAQNEKVDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHNIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDEVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACEGKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVADGKVFHAGTKLADDEQVVTSGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(28611..30200)
                     /gene="purH"
                     /locus_tag="ROH59_003265"
     CDS             complement(28611..30200)
                     /gene="purH"
                     /locus_tag="ROH59_003265"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDX4805710.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKCLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DANEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERIPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTKRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
BASE COUNT         7139 a         7906 c         8421 g         7043 t
ORIGIN      
        1 gcgactgacg gcccgatgcc gcagactcgt gagcacatcc tgctgggtcg tcaggtaggc
       61 gttccgtaca tcatcgtgtt cctgaacaaa tgcgacatgg ttgatgacga agagctgctg
      121 gaactggttg aaatggaagt tcgtgaactt ctgtctcagt acgacttccc gggcgacgac
      181 actccgatcg ttcgtggttc tgctctgaaa gcgctggaag gcgacgcaga gtgggaagcg
      241 aaaatcctgg aactggctgg cttcctggat tcttacattc cggaaccaga gcgtgcgatt
      301 gacaagccgt tcctgctgcc gatcgaagac gtattctcca tctccggtcg tggtaccgtt
      361 gttaccggtc gtgtagaacg cggtatcatc aaagttggtg aagaagttga aatcgttggt
      421 atcaaagaga ctcagaagtc tacctgtact ggcgttgaaa tgttccgcaa actgctggac
      481 gaaggccgtg ctggtgagaa cgtaggtgtt ctgctgcgtg gtatcaaacg tgaagaaatc
      541 gaacgtggtc aggtactggc taagccgggc accatcaagc cgcacaccaa gttcgaatct
      601 gaagtgtaca ttctgtccaa agatgaaggc ggtcgtcata ctccgttctt caaaggctac
      661 cgtccgcagt tctacttccg tactactgac gtgactggta ccatcgaact gccggaaggt
      721 gtagagatgg taatgccggg cgacaacatc aaaatggttg ttaccctgat ccacccgatc
      781 gcgatggacg acggtctgcg tttcgcaatc cgtgaaggcg gccgtaccgt tggcgcgggc
      841 gttgtagcaa aagttctgag ctaattgccg ataacatttg acgcaatgcg cactaaaagg
      901 gcatcatttg atgccctttt tgcacgcttt cgtaccagaa cctggctcat cagtgatttt
      961 ctttgtcata atcattgctg agacaggctc tgttgagggc gtataatccg aaaagctaat
     1021 acgcgtttcg atttggtttg cctcgcgatc gcggggtgaa aatgtttgta gaatacttct
     1081 gacaggttgg tttatgagtg cgaataccga agctcaagga agcgggcgcg gcctggaagc
     1141 gatgaagtgg gtcgttgtgg tggcattgct cctggtagcg attgtcggca actaccttta
     1201 tcgcgacatt atgctgccgc tgcgtgcgct ggccgtagta attctgattg ctgcagcggg
     1261 tggtgtcgcg ctgttaacga caaaaggtaa agcaaccgtt gcttttgccc gtgaagcgcg
     1321 taccgaagtc cgtaaggtca tttggccgac tcgccaggaa acattgcaca ccacgctgat
     1381 tgtggctgcg gttaccgcag taatgtcact gatcctgtgg ggactggatg gtattctggt
     1441 tcgcctggta tcctttatca ctggcctgag gttctgagat gtctgaagct cctaaaaagc
     1501 gctggtacgt cgttcaggcg ttttccggtt ttgaaggccg cgtagcaacg tcgctgcgtg
     1561 agcatatcaa attacacaac atggaagagt tgtttggtga agtcatggta ccaaccgaag
     1621 aagtggttga aatccgtggc ggtcagcgtc gcaaaagcga acgtaaattc ttccctggct
     1681 acgtcctcgt tcagatggtg atgaacgacg cgagctggca cctggtgcgc agcgtaccgc
     1741 gtgtgatggg cttcatcggc ggtacttccg atcgtcctgc gccaatcagc gataaagaag
     1801 tcgatgcgat tatgaaccgc ctgcagcagg ttggtgataa gccgcgtccg aaaacgttgt
     1861 ttgaaccggg tgaaatggtc cgtgttaatg atggtccgtt cgctgacttc aacggcgttg
     1921 ttgaagaagt tgattacgag aaatctcgtc tgaaagtgtc tgtttctatc ttcggtcgtg
     1981 cgacccctgt agagctggac ttcagccagg ttgaaaaagc ttaacccagc gatcaaaaaa
     2041 gcggcgattt aatcgttgca caaggcgcga gattggaata caatttcgcg ccttttgttt
     2101 ttatgggcct tgcccgtaaa acgatttttt atatcacggg gagcctctca gaggcgttat
     2161 tacccaactt gaggaattta taatggctaa gaaagtacaa gcctatgtca agctgcaggt
     2221 tgcagctggt atggctaacc cgagtccgcc agtaggtccg gctctgggtc agcagggcgt
     2281 aaacatcatg gaattctgca aagcgttcaa cgcaaaaact gattccatcg aaaaaggtct
     2341 gccgattccg gtagtaatca ctgtttacgc tgaccgttct ttcactttcg ttaccaagac
     2401 tccgccggca gcagttctgc tgaaaaaagc ggctggtatc aagtctggtt ccggtaagcc
     2461 gaacaaagac aaagtgggta aaatttcccg cgctcaactg caggaaatcg cgcagaccaa
     2521 agctgccgac atgactggtg ccgacattga agcgatgact cgctccatcg aaggtactgc
     2581 acgttccatg ggcctggtag tggaggacta agaaatggct aaactgacca agcgcatgcg
     2641 tgttatccgc gagaaagttg atgcaaccaa acagtacgac atcaacgaag ctatcgctct
     2701 gctgaaagag ctggcgactg ctaaattcgt agaaagcgtg gacgtagctg ttaacctcgg
     2761 catcgacgct cgtaaatctg accagaacgt acgtggtgca actgtactgc cgcacggtac
     2821 tggccgttcc gttcgcgtag ccgtatttac ccagggtgca aatgctgaag ctgctaaagc
     2881 tgcaggtgct gaactggtag gtatggaaga tctggctgaa cagatcaaga aaggcgaaat
     2941 gaactttgac gttgttattg cttctccgga tgcaatgcgc gttgttggcc agctgggcca
     3001 ggttctgggt ccgcgcggcc tgatgccaaa cccgaaagtg ggtactgtaa cgccgaacgt
     3061 tgctgaagcg gttaaaaacg ctaaagctgg ccagattcgt taccgtaacg acaaaaacgg
     3121 catcatccac accaccatcg gtaaagtaga ctttgacgct gacaaactga aagaaaacct
     3181 ggaagctctg ctggttgcgc tgaaaaaagc aaaaccgact caggcgaaag gcgtgtacat
     3241 caagaaagtt agcatctcta ccaccatggg tgcaggtgtt gcagttgacc aggctggcct
     3301 gagcgcttct gtaaactaat gcctttacgt gggcggtgat tttgtctaca atcttacccc
     3361 cacgtacgct aacgaaagtt agcagctaaa aagatttgtt cgttggagcc tggcctatcc
     3421 aggcctccgt cgaagaccgc aggagtttcg caagaaactt aatcccctgc gtagacggtg
     3481 acagaacgct aagattattc ttttatattc tggcttgttt ctgctcaccg taattaagac
     3541 gctctctccg tttggaggag tgaagtgagt tccagagatt ttctctggca aacatccagg
     3601 agcaaagcta atggctttaa atcttcaaga caaacaagcg attgttgctg aagtcagcga
     3661 agtagccaaa ggcgcgctgt ctgcagtagt tgcggattcc cgtggcgtaa ctgtagataa
     3721 aatgactgaa ctgcgtaaag caggtcgcga agctggcgta tacatgcgtg ttgttcgtaa
     3781 caccctgctg cgccgtgctg ttgaaggtac tccgttcgag tgcctgaaag acgcgtttgt
     3841 tggtccgacc ctgattgcat actctatgga acacccgggc gctgctgctc gtctgttcaa
     3901 agagttcgcg aaagcgaatg caaaatttga ggtcaaagcc gctgcctttg aaggtgagct
     3961 gatcccggcg tctcagatcg accgcctggc aactctgccg acctacgaag aagcaattgc
     4021 acgcctgatg gcaaccatga aagaagcttc ggctggcaaa ctggttcgta ctctggctgc
     4081 tgtacgcgat gcgaaagaag ctgcttaatc gcagttatct ttttaacgca ttcgcttacg
     4141 tataaactta ttctgatatt caggaacaat ttaaatgtct atcactaaag atcaaatcat
     4201 tgaagcagtt gcagctatgt ctgtaatgga cgttgtagaa ctgatctctg caatggaaga
     4261 aaaattcggt gtttccgctg ctgctgctgt agctgtagct gctggcccgg ttgaagctgc
     4321 tgaagaaaaa actgaattcg acgtaattct gaaagctgct ggcgctaaca aagttgctgt
     4381 tatcaaagca gtacgtggcg caactggcct gggtctgaaa gaagctaaag acctggttga
     4441 atctgcaccg gctgctctga aagaaggcgt gagcaaagac gacgcagaag cactgaaaaa
     4501 agctctggaa gaagctggcg ctgaagttga agttaaataa gccaaccctt ccggttgcag
     4561 cctgagaaat caggctgatg gctggtgact ttttagtcac cagccttttt gcgctgtaag
     4621 gcgccagtag cgtttcacac tgtttgacta ctgctgtgcc tttcaatgct tgtttctatc
     4681 gacgacttaa tatactgcga caggacgccc gttctgtgta aatcgcaatg aaatggttta
     4741 agcgtgatag caacaggcat tgcggaaagt gttccatttt ccggtcaaca aaatagtgtt
     4801 gcacaaactg tccgctcaat ggacagatgg gtcgacttgt cagcgagctg aggaacccta
     4861 tggtttactc ctataccgag aaaaaacgta ttcgtaagga ttttggtaaa cgtccacaag
     4921 ttctggatgt accttatctc ctttctatcc agcttgactc gtttcagaaa tttatcgagc
     4981 aagatcctga agggcagtat ggtctggaag ctgctttccg ttccgtattc ccgattcaga
     5041 gctacagcgg taattccgag ctgcaatacg tcagctaccg ccttggcgaa ccggtgtttg
     5101 acgtccagga atgtcaaatc cgtggcgtga cctattccgc accgctgcgc gttaaactgc
     5161 gtctggtgat ctatgagcgc gaagcgccgg aaggcaccgt aaaagacatt aaagaacaag
     5221 aagtctacat gggcgaaatt ccgctcatga cggacaacgg tacctttgtt atcaacggta
     5281 ctgagcgtgt tatcgtttcc cagctgcacc gtagtccggg cgtcttcttt gactccgaca
     5341 aaggtaaaac ccactcttcg ggtaaagtgc tgtataacgc gcgcatcatc ccttaccgtg
     5401 gttcctggct ggacttcgaa ttcgatccga aggacaacct gttcgtacgt atcgaccgtc
     5461 gccgtaaact gcctgcgacc atcattctgc gtgccctgaa ctacaccaca gagcagatcc
     5521 tcgacctgtt ctttgaaaaa gttatctttg aaatccgtga taacaagctg cagatggaac
     5581 tggtgccgga acgcctgcgt ggtgaaaccg catctttcga catcgaagct aacggtaaag
     5641 tgtacgtaga aaaaggccgc cgtattactg cgcgccacat tcgccagctg gaaaaagacg
     5701 acgtcaaact gatcgaagtc ccggttgagt acatcgcagg taaagtggtt gctaaagact
     5761 atattgatga gtctaccggc gagctgatct gcgcagcgaa catggagctg agcctggatc
     5821 tgctggctaa gctgagccag tctggtcaca agcgtatcga aacgctgttc accaacgatc
     5881 tggatcacgg cccatatatc tctgaaacct tacgtgtcga cccaactaac gaccgtctga
     5941 gcgcactggt agaaatctac cgtatgatgc gccctggcga gccgccgact cgtgaagcag
     6001 ctgaaagcct gtttgagaac ctgttcttct ccgaagaccg ctatgacctg tctgcggttg
     6061 gtcgtatgaa gttcaaccgt tctctgctgc gcgaagaaat cgaaggttcc ggtatcctga
     6121 gcaaagacga catcattgat gttatgaaaa agctcatcga tatccgtaac ggtaaaggcg
     6181 aagtcgatga tatcgaccac ctcggcaacc gtcgtatccg ttctgttggc gaaatggcgg
     6241 aaaaccagtt ccgcgttggc ctggtacgtg tagagcgtgc ggtgaaagag cgtctgtctc
     6301 tgggcgatct ggataccctg atgcctcagg atatgatcaa cgccaagccg atttccgcag
     6361 cagtgaaaga gttcttcggt tccagccagc tgtctcagtt tatggaccag aacaacccgc
     6421 tgtctgagat tacgcacaaa cgtcgtatct cggcactcgg cccaggcggt ctgacccgtg
     6481 aacgtgcagg cttcgaagtt cgagacgtac acccgactca ctacggtcgc gtatgtccaa
     6541 tcgaaacccc tgaaggtccg aacatcggtc tgatcaactc cctgtccgtg tacgcacaga
     6601 ctaacgaata cggcttcctt gagactccgt atcgtaaagt gaccgacggt gttgtaactg
     6661 acgaaattca ctatctgtct gctatcgaag aaggcaacta cgttatcgcc caggcgaact
     6721 ccaacctgga tgaagaaggc cacttcgtag aagacctggt aacttgccgt agcaaaggcg
     6781 aatccagctt gttcagccgc gaccaggttg actacatgga cgtatccacc cagcaggtgg
     6841 tatccgtcgg tgcgtccctg atcccgttcc tggaacacga tgacgccaac cgtgcattga
     6901 tgggtgcgaa catgcaacgt caggccgttc cgactctgcg tgctgataag ccgctggttg
     6961 gtacgggtat ggaacgtgct gttgccgttg actctggtgt aactgcggtt gctaaacgtg
     7021 gtggtgtcgt tcagtacgtg gatgcttccc gtatcgttat caaagttaac gaagacgaga
     7081 tgtatccggg tgaagcaggt atcgacatct acaacctgac caagtacacc cgttctaacc
     7141 agaacacctg tatcaaccag atgccgtgtg tgtctctggg tgaaccggta gaacgtggcg
     7201 acgtgctggc agacggtccg tccaccgacc tcggtgaact ggcgcttggt cagaacatgc
     7261 gcgtagcgtt catgccgtgg aatggttaca acttcgaaga ctccatcctc gtatccgagc
     7321 gtgttgttca ggaagaccgt ttcaccacca tccatattca ggaactggcg tgtgtgtccc
     7381 gtgataccaa gctggggccg gaagagatca ccgctgacat cccgaacgtg ggtgaagctg
     7441 cgctctccaa actggatgaa tccggtatcg tttacattgg tgcggaagtg accggtggcg
     7501 acattctggt tggtaaggta acgccgaaag gtgaaactca gctgacccca gaagaaaaac
     7561 tgctgcgtgc gatcttcggt gagaaagcgt ctgacgttaa agactcttct ctgcgcgtac
     7621 caaacggtgt atccggtacg gttatcgacg ttcaggtctt tactcgcgat ggcgtagaaa
     7681 aagataaacg tgcgctggaa atcgaagaaa tgcagctcaa acaggcgaag aaagacctgt
     7741 ctgaagaact gcagatcctc gaagcaggtc tgttcagccg tatccgtgct gtgctggtag
     7801 ccggtggcgt tgaagctgag aagctcgaca aactgccgcg cgatcgctgg ctggagctgg
     7861 gcctgaccga cgaagagaaa caaaatcagc tggaacagct ggctgagcag tatgacgaac
     7921 tgaaacacga gttcgagaag aaactcgaag cgaaacgccg caaaatcacc cagggcgacg
     7981 atctggcacc gggcgtgctg aagattgtta aggtatatct ggcggttaaa cgccgtatcc
     8041 agcctggtga caagatggca ggccgtcatg gtaacaaggg tgtaatttct aagatcaacc
     8101 cgatcgaaga tatgccttac gatgaaaacg gtactccggt agacatcgta ctgaacccgc
     8161 tgggcgtacc gtctcgtatg aacattggtc agatcctcga aacccacctg ggtatggctg
     8221 cgaaaggtat cggcgacaag atcaacgcca tgctgaaaca gcagcaagaa gtcgcgaaac
     8281 tgcgcgaatt catccagcgt gcgtacgatc tgggcgctga tgttcgtcag aaagttgacc
     8341 tgagtacctt cagcgatgaa gaagttatgc gtctggctga aaacctgcgc aaaggtatgc
     8401 caatcgcaac gccggtcttc gacggtgcga aagaagcaga aattaaagag ctgctgaaac
     8461 ttggcgacct gccgacttct ggtcagatcc gcctgtacga cggtcgcact ggtgaacagt
     8521 tcgaacgtcc ggtaaccgtt ggttacatgt acatgctgaa actgaaccac ctggtcgacg
     8581 acaagatgca cgcgcgttcc accggttctt acagcctggt tactcagcag ccgctgggtg
     8641 gtaaggcaca gttcggtggt cagcgtttcg gggagatgga agtgtgggcg ctggaagcat
     8701 acggcgcagc atacaccctg caggaaatgc tcaccgttaa gtctgatgac gtgaacggtc
     8761 gtactaagat gtataaaaac atcgtggacg gcaaccatca gatggagccg ggcatgccag
     8821 aatccttcaa cgtattgttg aaagagattc gttcgctggg tatcaacatc gaactggaag
     8881 acgagtaatt ctcgctcaaa caggtcactg ctgtcggggt aaaacccggc agcggattgt
     8941 gctaactccg acgggagcaa atccgtgaaa gatttattaa agtttctgaa agcgcagact
     9001 aaaaccgaag agtttgatgc gatcaaaatt gctctggctt cgccagacat gatccgttca
     9061 tggtctttcg gtgaagttaa aaagccggaa accatcaact accgtacgtt caaaccagaa
     9121 cgtgacggcc ttttctgcgc ccgtatcttt gggccggtaa aagattacga gtgcctgtgc
     9181 ggtaagtaca agcgcctgaa acaccgtggc gtcatctgtg agaagtgcgg cgttgaagtg
     9241 acccagacta aagtacgccg tgagcgtatg ggccacatcg aactggcttc cccgactgcg
     9301 cacatctggt tcctgaaatc gctgccgtcc cgtatcggcc tgctgctcga tatgccgctg
     9361 cgcgatatcg aacgcgtact gtacttcgaa tcctatgtgg ttatcgaagg tggtatgacc
     9421 aacctggagc gtcagcagat cctgactgaa gagcagtatc tggacgcgct ggaagagttc
     9481 ggtgacgaat tcgacgcgaa gatgggggcg gaagcaatcc aggccctgct gaagagcatg
     9541 gatctggagc aagagtgcga acagctgcgt gaagagctga acgaaaccaa ctccgaaacc
     9601 aagcgtaaaa agctgaccaa gcgtatcaaa ctgctggaag cgttcgttca gtctggtaac
     9661 aaaccagagt ggatgatcct gaccgttctg ccggtactgc cgccagatct gcgtccgctg
     9721 gttccgctgg atggtggtcg tttcgcgact tctgacctga acgatctgta tcgtcgcgtc
     9781 attaaccgta acaaccgtct gaaacgtctg ctggacctgg ctgcgccgga tatcatcgta
     9841 cgtaacgaaa aacgtatgct gcaggaagcg gtagacgccc tgctggataa cggtcgtcgc
     9901 ggtcgtgcaa tcaccggttc taacaagcgt cctctgaaat ctttggccga catgatcaaa
     9961 ggtaaacagg gtcgtttccg tcagaacctg ctcggtaagc gtgttgacta ctccggtcgt
    10021 tctgtaatca ccgtaggtcc atacctgcgt ctgcatcagt gcggtctgcc gaagaaaatg
    10081 gcgctggagc tgttcaaacc gttcatctac ggcaagctgg aactgcgtgg tcttgctacc
    10141 accatcaaag ctgcgaagaa aatggttgag cgcgaagaag ctgtcgtttg ggatatcctg
    10201 gacgaagtta tccgcgaaca cccggtactg ctgaaccgtg caccgactct gcaccgtctg
    10261 ggtatccagg catttgaacc ggtactgatc gaaggtaaag ctatccagct gcacccgctg
    10321 gtttgtgcgg catataacgc cgacttcgat ggtgaccaga tggccgttca cgtaccgctg
    10381 acgctggaag cccagctgga agcgcgtgcg ctgatgatgt ctaccaacaa catcctgtcc
    10441 ccggcgaacg gcgaaccaat catcgttccg tctcaggacg ttgtactggg tctgtactac
    10501 atgacccgcg actgtgttaa cgccaaaggc gaaggcatgg tgctgactgg cccgaaagaa
    10561 gcagaacgtc tgtatcgctc tggtctggct tctctgcatg cgcgcgttaa agtgcgtatc
    10621 accgagtatg aaaaagatgc taacggtgaa ttagtggcga aaaccagcct gaaagacacg
    10681 actgttggcc gtgccattct gtggatgatt gtaccgaaag gtctgcctta caccatcgtc
    10741 aaccaggcgc tgggtaaaaa agcaatctcc aaaatgctga acacctgcta ccgcattctc
    10801 ggtctgaaac cgaccgttat ttttgcggac cagatcatgt ataccggctt tgcatatgca
    10861 gcgcgttctg gtgcatctgt tggtatcgat gacatggtca tcccggagaa gaaacacgaa
    10921 atcatctccg aggcagaagc agaagttgct gaaattcagg agcagttcca gtctggtctg
    10981 gtaactgcgg gcgaacgcta caacaaagtt atcgatatct gggctgcggc gaacgatcgt
    11041 gtatccaaag cgatgatgga taacctgcaa actgaaaccg ttattaaccg tgacggtcag
    11101 gaagagaagc aggtttcctt caacagcatc tacatgatgg ccgactccgg tgcgcgtggt
    11161 tctgcggcac agattcgtca gcttgctggt atgcgtggtc tgatggcgaa gccggatggc
    11221 tccatcatcg aaacgccaat caccgcgaac ttccgtgaag gtctgaacgt actccagtac
    11281 ttcatctcca cccacggtgc tcgtaaaggt ctggcggata ccgcactgaa aacggcgaac
    11341 tccggttacc tgactcgtcg tctggttgac gtggcgcagg acctggtggt taccgaagac
    11401 gattgtggta cccatgaagg tatcatgatg actccggtta tcgagggtgg tgacgttaaa
    11461 gagccgctgc gcgatcgcgt attgggtcgt gtaactgctg aagacgttct gaagccgggt
    11521 actgctgata tcctcgttcc gcgcaacacg ctgctgcacg aacagtggtg tgacctgctg
    11581 gaagagaact ctgtcgacgc ggttaaagta cgttctgttg tatcttgtga caccgacttt
    11641 ggtgtatgtg cgcactgcta cggtcgtgac ctggcgcgtg gccacatcat caataaaggt
    11701 gaagcaatcg gtgttatcgc ggcacagtcc atcggtgaac cgggtacaca gctgaccatg
    11761 cgtacgttcc acatcggtgg tgcggcatct cgtgcggctg ctgaatccag catccaggtg
    11821 aaaaacaaag gtagcatcaa gctcagcaac gtgaagtcgg ttgtgaactc cagcggtaaa
    11881 ctggttatca cttcccgtaa caccgaactg aaactgatcg acgaattcgg tcgtaccaaa
    11941 gaaagctaca aagtacctta cggtgcggta ctggcgaaag gcgatggcga acaggttgct
    12001 ggcggcgaaa ccgttgcaaa ctgggacccg cacaccatgc cggttatcac cgaagtaagc
    12061 ggttttgtac gctttactga catgatcgac ggccagacca ttactcgtca gaccgacgaa
    12121 ttgaccggtc tgtcttcgct ggtggttctg gattccgcag aacgtaccgc aggtggtaaa
    12181 gatctgcgtc cggcactgaa aatcgttgat gctcagggta acgacgttct gatcccgggt
    12241 accgatatgc ctgcgcagta cttcctgccg ggtaaagcga ttgttcagct ggaagatggc
    12301 gtacagatca gctctggtga caccttggcg cgtattccgc aggaatccgg cggtaccaag
    12361 gacatcaccg gtggtctgcc gcgcgttgcg gacctgttcg aagcacgtcg tccgaaagag
    12421 ccggcaatcc tggctgaaat cagcggtatc gtttccttcg gtaaagaaac caaaggtaaa
    12481 cgtcgtctgg ttatcacccc ggtagacggt agcgatccgt acgaagagat gattccgaaa
    12541 tggcgtcagc tcaacgtgtt cgaaggtgaa cgtgtagaac gtggtgacgt aatttccgac
    12601 ggtccggaag cgccgcacga cattctgcgt ctgcgtggtg ttcatgctgt gactcgttac
    12661 atcgttaacg aagtacagga cgtataccgt ctgcagggcg ttaagattaa cgataaacac
    12721 atcgaagtta tcgttcgtca gatgctgcgt aaagctacca tcgttaacgc gggcagctcc
    12781 gacttcctgg aaggtgaaca ggttgaatac tctcgcgtca agatcgcaaa ccgcgaactg
    12841 gaagcgaacg gtaaagtggg tgcaacttac tcccgcgatc tgctgggtat taccaaagcg
    12901 tctctggcaa ccgagtcctt catctccgcg gcatcgttcc aggagaccac tcgcgtgctg
    12961 accgaagcag ccgttgcggg caaacgcgac gaactgcgcg gcctgaaaga gaacgttatc
    13021 gtgggtcgtc tgatcccggc aggtaccggt tacgcgtacc accaggatcg tatgcgtcgc
    13081 cgtgctgcgg gtgaagctcc ggctgcaccg caggtgactg cagaagacgc atctgccagc
    13141 ctggcagaac tgctgaacgc aggtctgggc ggttctgata acgagtaatc gttaatccgc
    13201 aaataacgta aaaacccgct tcggcgggtt tttttatggg tgttattcag agggcaaagt
    13261 cttcacggga aatattaaga aaggcagggc gaaacgagga agaagctttt cgccctggac
    13321 aacattcctg ctgacggcac taccataaaa aaacacaacg ctttcaacaa ccttgcgttt
    13381 ttcatcttcc gtagcggctc ggaataaatt tacgttctta cattctgtct catggccttt
    13441 gcgatgggcg tcccagatag ctgtcccagt ctttccatac cggctgcaaa ccctgagcgg
    13501 ttaacgcggc agcaaccgct tccggtctgc gatcgtcgtg cggtgagaac tgttccagct
    13561 cggggtggtt gtcggcatag ccacctggct gcgttttcga aaaagcgctg acgttattaa
    13621 ttgccagcgg aatcacgcga tcgcgaaacc acggtgattc ccgcgtggag agtgacagtt
    13681 caatctccgg tgcaagcagc cggaaagcgc agatggcttg cactaactgg cgttcatcca
    13741 taatcgacgc aggctcaatg ccgccagtac atggacgcag gcgtgggaag gagacagagt
    13801 agcggctttg ccagtaatgc tgttgcagcc atagcaaatg ttcggcaacc atatagcagt
    13861 caactcgcca gctgtcggaa aggccgatta gcgcgccgag gcctatctta tcaatccccg
    13921 cacgccctag ccgatccggc gtttccagcc gccagaagaa gtcctgtttt ttacctttca
    13981 gatgatgatg ggcataagtc gcctcatgat atgtctcctg ataaaccatt actccatcga
    14041 ggccaagctg ttttaactcg gcatattccg cctccgccag cggttgcact tccatctgta
    14101 gtgaagagaa ctgttcacgc agggcaggga gatgacgacg aaagtaatcc atccccactt
    14161 tcgcctgatg ttcaccagtg actaatagca gatgttcaaa gcccatctcc cgtatagcgg
    14221 cgctttccct ggcaatatcc gcttcatcca gcgttttgcg cttgatgcgg ttgctcatag
    14281 aaaatccgca ataagtacag tcgttagcgc aaagattgga aagataaagc gggacgtaga
    14341 agctgacgac gttgccaaat cgctgacgag tcagacgttg cgctcgctgg gccagtggtt
    14401 ccagatagcc actggcggcg ggtgatagca atgccatcat gtcgtcgcgg gtgagttgcg
    14461 aggcatttag cgcccgctct acgtcagcag ccgttttgcc gttgatacgc aggtggatgt
    14521 catcccagtc cagttgtcgc cagcgatcgc tgaaggtttt catgccgatg cctccagaaa
    14581 tccagtcagc gggctggtgg catgagcaaa atgactgcgg ctgcccggtc cggactgacg
    14641 tgccagcagg cctgcttcta ccgccagacg aaatgccttc gccatgttga cgggatcgtc
    14701 cgcgacggca atcgccgtat tcactaacac cgcgtcggcc cccatttcca gcgcctgcgc
    14761 ggcatggctg ggaacgccga tgccagcatc gacaaccacc ggaacggtgg cctgctggat
    14821 aataatctcc agcatggcgc gggtttccag tccctgattc gagccaatcg gcgcgccgag
    14881 cggcatcacc gctgcacagc cgacttcttc cagacgttta cacaataccg gatcggcccc
    14941 gcagtaaggc agcacgacaa atccctgttg taccagcgtt tcggcggctt tcagggtttc
    15001 gatgggatcg ggcaacagcc agcgggcgtc agggtgaatc tccaatttta gccagtttgt
    15061 gcctaacgct tcacgtgcca gatgggcggc gaaaatggct tcttccgcgg ttttcgcccc
    15121 ggaagtattc ggcagcaggg ccacacccgc cgcgataagc ggttcgagga tagcgtcgtt
    15181 gtgctggcgc aagtcgacac gtttcatcgc cagcgtcacc agttggctgc cggaagcgcg
    15241 aatagactcc accatcagtt gtgaagaggc gaattttccg gtgccagtaa acagatgtga
    15301 atcaaacgtt ttgtccgcaa tatgtaacat ctcaaccccc tgcaataact tgaaaaagca
    15361 ggatctggtc gccatcctgc acgatatgtt gcgcccattg ttcccgcggg acgatttgct
    15421 gattaatcgc cagtgccgca cctgcttgtt gttgttcgag ttgctccagc agttcgtgaa
    15481 cagttagttc ggcgacacac tgcatcggtt gatcgttaaa caggatctgc attgcatcct
    15541 ccacataccg ggcaaccgct ggcgcggcgc aacgtcagac tgcgccactg gctcgattta
    15601 ccgtcgaaca gtcggagttc tcccgcaggc gtctctatac cacttaataa cttaatcgct
    15661 tccagtgcct gtaaagtgcc cataaccccg accaccgggc caaccacgcc cgccgtgcgg
    15721 cagttgcgtt ctggctcctg gttatctggc cacaggcagc ggtaacatcc ctgctcccag
    15781 ggcggcgtca gtaccatcaa ctgaccgcca aatccgaccg cgctggcggt gataagcggc
    15841 gtgttgagtg ccacgcaggt ggcattaatc tcctggcgag tcgccatatt gtcagtacag
    15901 tcgagcacca catcggcttg tgcaaccgca tcttttaacg tctcacccgt taaccgttgt
    15961 tgtaatgcca tcagtcgaat atcgggattc aactgtgtca gtcgctgttg gctgacctgt
    16021 gatttcgggc gatcgatatc ttcagtggta aagaggattt gtcgttgcag attgcttaaa
    16081 tgcacatcgt cgtcatctgc cagtaccagc gtcccgacgc cagcccccgc caggtatagc
    16141 gcagcaggtg tacccagccc gccaagacca ataatcagca cctggctgtc gagcagtttt
    16201 tgctgcccgt ccagagcgat atcgtcgagc aggatttggc ggctataacg cataaagtca
    16261 cggtcattca tcgccaactc ctgcaatttc cagcagctgt gccgttgcca aacgccagtc
    16321 tgcggcttga gtaatggcgc tgacgacggc gatactgccg acacccgttg ctatcaccgc
    16381 aggcgcgcgc gccagactga taccgccaat cgccacggtg ggataatccg ccaggcgctc
    16441 aacatgccgt gccagctgtt ccagtccctg cggtgcagaa ggcatctgtt tggtttgtgt
    16501 cggaaacaca tgtcccagcg cgatataaga aggacgtgcc gccagcgcga cgtcgatctc
    16561 catatcgtca tgagtcgaaa cgcccagccg caggcccgct gcacggatgg cattgagatc
    16621 ggtggcttgc aaatcttcct gccccagatg gacgccatac gcctgatgct taatcgccag
    16681 ccgccagtaa tcgttgataa acaatcgcgc gttatagcgg cggcccagcg caattgccgc
    16741 caccacatcg gcttctacct cttcatcgcg ctgatctttg atgcgtagct ggagagtacg
    16801 tacgcctgca tccaacagac gttcgatcca ctgtacgctg tcaaccaccg ggtacagtcc
    16861 taaacgaaag ggtacaggag gaaactcagg ctgatacatc acgcttcctc cttacgcagg
    16921 tagatttctc cgcctctggc gcggaagttc tccgacatat ccgccattcc cacttcaatg
    16981 gtttgcgcgg cggcgtaatc acgcacttcc tggctgattt tcatcgagca gaatttcggt
    17041 ccacacatgg agcaaaaatg ggcgacttta ccggactctt gcggcagggt ttcatcgtga
    17101 taagcgcggg cagtaaacgg gtcgagggcc agattaaact ggtcttccca gcgaaattcg
    17161 aagcgggctt tcgacatggc gttatcgcga atttgcgcgc ccggatgccc tttcgccagg
    17221 tcggcggcgt gagcggcaat cttataggtg ataagcccct gtttaacatc ttctttattt
    17281 ggcaggccca gatgctcttt cggcgttacg tagcagagca tcgcgcagcc aaaccagcca
    17341 atcatcgccg cgccaatccc tgacgtgaag tggtcatagc ccggcgcgat atcggtagtt
    17401 agcggcccca gagtgtaaaa cggcgcttcg tggcagtgct ctaactcctc ggtcatattg
    17461 cggcgaatca tctgcatcgg cacgtggcct gggccttcaa tcatcacctg cacgtcatat
    17521 tcccaggcga ttttggtcag ttcgcccagc gtatgcagct cggcaaactg tgcttcatcg
    17581 ttggcgtcct gaatagaacc ggggcgcagg ccgtcgccca gcgacagcga aacgtcataa
    17641 gcagcacaga tttcacaaat ttcgcggaag tgttgataga ggaaattttc ctgatgatgg
    17701 gagaggcacc atttcgccat aatcgaaccg ccgcgagaga cgataccggt caggcgtttc
    17761 gcggtcatcg gcacgtagcg cagcagcacc cccgcatgga tagtgaagta atccacacct
    17821 tgctcggctt gttccagcag ggtgtcgcgg aagacttccc aggtaagatc ttcagcgatc
    17881 ccgttcacct tctccagtgc ctggtagatc ggcactgtac cgatcggcac cgggctgtta
    17941 cgcaaaatcc actcgcgggt ttcgtgaata tagcgaccag tggaaagatc catcacggta
    18001 tccgctcccc agcgcgtgga ccataccagt ttttccactt cttcttcgat ggaagaagtg
    18061 accgccgagt tgccgatatt ggcgttaact tttaccagga agttacggcc aataatcatc
    18121 ggctccgatt ccggatgatt aatgttggcc gggataatcg cacgtccggc agcaacttca
    18181 tcacggacaa attccgcagt gatattttcc ggcagacgtg cgccaaagct cattcccgga
    18241 tgctggtggc gtaaaacttc gctacgtatg cgctcgcgac ccatattctc gcgaatggcg
    18301 atgaattcca tttctggcgt gatgataccc ttgcgggcgt agtgcagttg ggtgacgcgg
    18361 cgtcctgctt tggcgcgttt tggcgttaat acgccgctaa aacgcagctc gtcaaggcca
    18421 tcatctgcca gccgcgcttt agtgtaatcg gaactgcgta cggtaagttc ttcggtatcg
    18481 ccgcgcgcat cgatccacgg ctggcgtagt tttgccagcc cttgctgcac gttaatggca
    18541 atctgcggat cgccatacgg gccggaggtg tcgtagaccg gaatcgcttc gttttcttcg
    18601 tactgcggct gttctttgct gccgccaatt agcgtcgggc taagctggat ctcacgcatc
    18661 ggcacgcgca cgccggggtg tgtgccagtg atgtaaatgc gttttgagtt gggaaaggcg
    18721 gagccttcca gggtgtcgat aaaatgttgg gcctgggcgc gctgttcgcg gcgggtcagt
    18781 tttgttgcag acatagctca ttccaaaaag ttaaggacgt ggcttgtcag acgacggatg
    18841 aagcaagaga cgatcgccgc aaaggcgatg cgatagcaga ttaactcttg ttcccttcgc
    18901 aggtattagc ctgatcaggt tccgcggatc ccgaataaac ggtctcagcc agttaaggca
    18961 ctccgacaag aaattagccc cacaaacggg gcgttgaatg taaattacgc gttaacagcg
    19021 cagaactcaa gcaggatatt tgacgcgggc ggcgtcaagc accagtagaa tcagcttatc
    19081 ttccagcaca aagcgcgctt ccagtgcctc gccgatgtca gataaaacct gttgaaactc
    19141 aaggtaatta tcatgatcga tggcggtttc caggctggaa tcgtagtcat ccataatctg
    19201 ttgagtattg gcttcgagtt gcggccaaat cttcgcggcg cgcgcgagtt gcccgttgcc
    19261 ttccagctta tgaagaatgc gctcataaat actgaaatgt ccggcagaca agtaatcgac
    19321 caggctctga caaaaatcat caagggcttt ttcgtttagc ctcatgtacg attctttgcc
    19381 aggcttaatg ccaaccagat tgtagtaagc cacgagcaga tgcttacgta catgtagcca
    19441 gcgatcaacc agtttgttac ttcctctgac gcgctccgtc aggttatcga gctggttaag
    19501 catgattgac tccgcaagtt tgtattcaaa aactgctctg tgagaaatgt aaaaaccatg
    19561 ttaaacatgc cagtgatgca aaggtagtgc aagagctatg gatcgtataa ttgaaaaatt
    19621 agatcacggc tggtgggtcg tcagccatga acaaaaatta tggttgccga agggagaatt
    19681 gccatatggc gaagcggcaa atttcgatct tgtgggtcag cgcgcactac aaatcggcga
    19741 atggcagggg gaacctgttt ggttagtaca acagcagcgg cgtcacgata tggggtcggt
    19801 acgtcaggtc attgatctcg atgttgggct gtttcaactg gccggacgtg gcgtgcaact
    19861 ggcggagttt taccgatcgc ataaatactg tggttactgc gggcatgaaa tgtatccaag
    19921 caaaaccgaa tgggcgatgc tgtgcagcca ttgccgtgag cgttactacc cgcaaatcgc
    19981 cccctgcatt attgttgcca tccgtcgcga tgattcgatc ctcctcgccc agcatacccg
    20041 ccatcgtaac ggtgtccata cagtacttgc cggattcgtc gaagtgggtg aaaccctcga
    20101 gcaggcagtc gcgcgggaag tgatggaaga gagcggaatt aaagttaaaa acttgcgtta
    20161 cgtgacctcc caaccgtggc cgtttcctca gtcgttaatg accgcgttta tggcggaata
    20221 tgacagcggc gagatcgtga tcgacccgaa agaattgctt gaggcgaact ggtatcgcta
    20281 tgacgatttg ccgttactcc cgccgcccgg caccgtagcg cgccgtctga tagaagatac
    20341 ggtggcgatg tgtcgggcag agtatgagtg atgatacact gaccgcctga cgcactaagg
    20401 aacagccaaa atgaccgaac ttaaaaacga tcgttatctg cgggcgctgc tgcgccagcc
    20461 cgttgatgtc actccagtat ggatgatgcg ccaggcgggt cgctatctac cggaatataa
    20521 agccacgcgc gcccaggcgg gcgattttat gtcgctgtgc aaaaatgccg agctggcgtg
    20581 cgaagtgact ttgcaaccgc tgcgtcgcta tccgctggat gcggcgatcc tcttttccga
    20641 tatcctcacc gtgccagacg cgatgggttt agggctctat tttgaagccg gagaaggtcc
    20701 gcgttttacc tcgccagtca cctgcaaagc cgatgtcgat aaactgccaa ttccggaccc
    20761 ggaagatgag ctgggttacg tgatgaacgc ggtgcgtacc attcgtcgcg aactgaaagg
    20821 cgaagtgccg ctgattggtt tttccggcag cccgtggacg ctggcgacct acatggtgga
    20881 aggcggcagc agcaaagcgt tcaccgtgat caaaaaaatg atgtatgccg atccacaggc
    20941 gctgcacgcg ctactcgata aactggcgaa aagcgtcact ttgtatctga atgcgcagat
    21001 taaagccggt gctcaggcag tgatgatttt cgacacctgg ggcggcgtgc ttaccgggcg
    21061 cgattatcaa cagttctcgc tctattacat gcataaaatt gttgatggtt tactgcgtga
    21121 aaacgacggt cgccgcgtac cggtcacgct gtttaccaaa ggtggcggac agtggctgga
    21181 agcgatggca gaaaccggtt gcgatgcgct gggcctcgac tggacaacgg acatcgccga
    21241 tgcgcgccgt cgcgtgggca ataaagtcgc gctgcagggt aatatggacc cgtcgatgct
    21301 gtatgcgccg cctgcccgca ttgaagaaga agtggcgtct atacttgccg gtttcggtca
    21361 cggcgaaggc catgtcttta accttggtca cggcattcat caggatgtgc cgccagaaca
    21421 tgctggcgtg tttgtggagg cagtgcatcg cttgtctgaa cagtatcacc gctaaggagc
    21481 gattatggat ctcgcgtcat tacgcgctca acaaattgaa ctggcttctt ctgtgatccg
    21541 cgaggatcga ctcgataaag atccgccgga tctgatcgcc ggagccgatg tcggatttga
    21601 gcagggcgga gaagtgacgc gagcggcgat ggtgctgctg aaatacccct cgcttgagct
    21661 ggtggagtat aaagtggccc gcatcgccac caccatgcct tacattccag gttttctctc
    21721 gttccgcgaa tatcctgcgc tgctggcagc gtgggagatg ctgtcgcaaa agccggattt
    21781 agtgtttgtc gatggtcatg ggatctcgca tcctcgccgt cttggcgtag ccagccattt
    21841 tggcttattg gtggatgtgc cgaccattgg cgtggcgaaa aaacggctct gcggtaaatt
    21901 cgaaccgctc tccagcgaac cgggcgcgct ggcccctctg atggataaag gcgagcagct
    21961 ggcctgggtc tggcgcagca aagcgcgctg taacccgttg tttatcgcta ccggccatcg
    22021 ggtcagcgtg gacagcgcgc tggagtgggt acaacgctgc atgaaaggct atcgtctgcc
    22081 ggagccaacg cgctgggcgg acgcggtggc ctcggaacgt ccggcgttcg tgcgctatac
    22141 agcaaatcag ccctaattca ggtaaactgc ggataatttc cgtatttgag aactcaacat
    22201 gttacaaaac ccaattcatc tgcgtctgga gcgcctggca agctggcagc atgtcacttt
    22261 tatggcctgc ttatgcgaac gcatgtaccc caattacgcc gtattctgtc agcaaaccgg
    22321 cttcggcgat gggcagattt accgccgcat tctcgatctc atttgggaaa cgctgaccgt
    22381 caaagatgca aaagtaaatt tcgacagcca actggagaaa tttgaagaag cgattccttc
    22441 agccgacgat ttcgatctgt acggcgttta tccggcaatc gatgcttgcg tggcgttaag
    22501 tgaactggtt cattcgcgtt taagtggcga aacgctcgaa cacgcggtgg aagtgagtaa
    22561 gacctccatc acgaccgttg cgatgctgga aatgactcag gctggtcgcg aaatgagcga
    22621 tgaagagctc aaagaaaacc cagctgtaga gcaagaatgg gacattcagt gggaaatatt
    22681 ccgactttta gctgagtgtg aagaacgcga tatcgagctg ataaaaggcc ttagggcaga
    22741 cctgcgtgag gcgggtgaga gcaatattgg tataattttt cagcaataag accagaaaac
    22801 gtgatttaac gcctgatttg tcgtacctgg agtcttccct ttcgcccccc gtctggtcta
    22861 catttggggg gcgaaaaaaa gtggctatcg gtgcgtgtat gcaggagagt gctattctgg
    22921 catttccgtc gcactcgatg cttagcaagc gataaacaca ttgtaaggat aacttatgaa
    22981 caagactcaa ctgattgatg taattgcaga gaaagcagaa ctgtccaaaa cccaggctaa
    23041 agctgctctg gagtccactc tggctgcaat tactgagtct ctgaaagaag gcgatgctgt
    23101 acaactggtt ggtttcggta ccttcaaagt gaaccaccgc gctgagcgta ctggccgcaa
    23161 cccgcagacc ggtaaagaaa tcaaaattgc cgcagctaac gtaccggcat ttgtttctgg
    23221 caaggcactg aaagacgcag ttaagtaaga ttgcgtggca gtgaacagtt ttaacgaagg
    23281 ggtggtttca ccccttttgt ctttctggcg tcgatcattg atgctggcag gtgcgctgtt
    23341 tctcactgcc tgtagtcaca actcttcact tcctcccttt accgccagtg gatttgctga
    23401 agaccagggc gcggtacgca tctggcgaaa agacagcggc gataatgtgc atcttcttgc
    23461 cgtgtttagc ccgtggcgca gtggcgatac gacgacgcga gagtatcgct ggcagggcga
    23521 taacctcacg cttatcaata tcaacgttta cagcaaaccg ccggtaaaca tccgggcgcg
    23581 ttttgacgat cgcggtgact tgagctttat gcaacgtgaa tccgacgggc aaaagcagca
    23641 gctttccaat gatcagatcg atttataccg ttatcgtgcc gcgcagatcc gcgagattag
    23701 cgatgcctta cgccagggga gagtcgtgct gcgccagggg cgctggcatg cgatggagca
    23761 gactgtgacc acctgcgaag ggcaaaccat taaacctgat ttagattcgc aggcgatagc
    23821 gcatatcgag cgccgccaga gccgttcttc tgttgatgtc agcgtggcat ggctggaagc
    23881 gcccgaaggt tcgcaattac tgttggtggc aaactctgat ttctgtcgct ggcaacccaa
    23941 cgagaaaacg ttctgattta ccagtggccc atacccatat gaccgccacc accgcagccg
    24001 ccgtaaccca ttccggtacc gcgcggaata cccgcttcag ccatcgcaat atctcgtttc
    24061 acccgtaact catctaacga ctgacgcaaa ttctccatct ctttggcgac cgcgttaatt
    24121 ttgctgctat ccggtgggtt cgcggctaac agggcattgt attcataacg ctttgtcacc
    24181 agttgctgtt gcagtgcgct gctttgagcg taaaagtcat tatggatttt ctgccacgct
    24241 gtttgttgtt cgctggtcaa aggcgcggca ttttgctgcc acataccgtg tccgccgtga
    24301 gcaaatgccg atgtcgatcc catcgccatt gctgaaagcg ccatcattac cagggcaatt
    24361 ttcgtgttcc gtttcatggt taatcctcca gtggttgtct tacttcgggt attgcatctt
    24421 tcgtgccaac ggcgaaacgc tgatatgacg ggtaatctgg catgataaac gagtaaaaat
    24481 gactcgcctg ttgtgggtag cgagtcattt ttactcattg aaacttaagc ctttgtgtta
    24541 cagcgcaggg taagcgctga taaaagatgg catgatttct gctgtcagaa agggatgggc
    24601 aggcaaagaa gaagatgcgt tttatgcaac gttctaaaga ctccttagct aaatggttaa
    24661 gcgcgatcct ccccgtggtc attgttgggc tggtggggct gtttgcggtg acagtgattc
    24721 gcgattatgg gcgcgagact gccgccgcca gacaaacgct gctggaaaaa ggcagtgtac
    24781 ttatccgtgc tctcgaatcc ggctcgcgcg tcggaatggg gatgcgcatg catcatgcgc
    24841 agcagcaggc cttactggaa gaaatggccg ggcagcctgg agtacgttgg tttgcggtca
    24901 cggatgaaca aggaacaatc gtgatgcata gcaactccgg catggtggga aaacagcttt
    24961 attccccgca ggaaatgcag cagttacatc cgggagatga agaagcgtgg cggcggatcg
    25021 atagcgcaga cggcgagcct gttctggaaa tttatcgcca gtttcaaccg atgtttgctg
    25081 ctggaatgca ccggatgcgc catatgcagc agtatgccgc gacaccacaa gcaattttta
    25141 tcgctttcga cgccagtaac attgtgagtg ccgaagatcg tgagcagaga aacaccctga
    25201 ttatcctctt cgccctggcg acggtcttgc tggcaagcgt gttgtcattc ttctggtatc
    25261 gccgatatct gcgctcgggc cagctgttgc aggatgaaat gaagcgcaaa gagaagctgg
    25321 tggcactggg gcatcttgcg gcaggcgttg cccacgaaat ccgtaaccca ctttcctcga
    25381 ttaaagggct ggcgaaatac tttgccgaac gcgcgccagc agggggagaa gcgcatcaat
    25441 tggcgcaggt gatggcgaaa gaagccgacc gtttaaaccg cgtggtaagc gagctgctgg
    25501 aactggttaa gccaacgcat ctggctttgc aggcggtgga gctcaacacg ctgattagcc
    25561 actcattaca gctggtaagc caggatgcaa acagccggga gatccagtta cgctttaccg
    25621 ccaacgacac attaccggaa attcaggccg atccggacag gctgactcag gtcctgttga
    25681 atctctatct caacgctatt caggcgattg gtctgcatgg cgtgattagc gtgacggcca
    25741 gcgaaagcgg cgcgggcgtg aaaatcagcg ttaccgacag cggtaaggga attgcggcgg
    25801 atcagcttga agccatcttc actccgtact tcaccaccaa agccgaaggc accggactgg
    25861 ggctggcggt cgtgcataat attgttgaac aacacggtgg tacaattcag gttgcaagcc
    25921 aggaggggaa aggcgcaacg ttcaccctct ggcttccggt caatattacg cgtaaggacc
    25981 cacaaggatg acgcacgata atatcgatat tctggtggtg gatgatgaca ttagccactg
    26041 cactattttg caggctttac tgcgcggctg gggctataac gtcgcgctgg cgaacagcgg
    26101 gcgacaggcg ctggagcagg tgcgggaaca ggttttcgat cttgtgcttt gcgatgtgcg
    26161 aatggcagag atggacggca tcgccacgct aaaagagatc aaagcgttaa atccggcgat
    26221 tccggtactg attatgaccg cgtactccag cgtcgagacg gcggtagagg cactgaaaac
    26281 cggggcgctg gattacctca tcaagccgct ggatttcgat aacctgcagg caacgctgga
    26341 aaaggcgctc gcgcatacgc acagtatcga cgctgaaacg cctgcggtgt ctgccagcca
    26401 gttcggtatg gtcggtaaaa gcccggcgat gcaacacctg ctcagtgaaa tcgccctcgt
    26461 cgcgccatcg gaagccacgg tgctgatcca cggcgattcc ggtaccggta aagagctggt
    26521 cgccagggcg attcacgcca gtagcgcacg tagcgaaaaa ccgctggtaa cgctcaactg
    26581 tgcggcactc aacgaatcct tgctggaatc tgaattgttc ggtcatgaaa aaggggcgtt
    26641 taccggagcc gacaaacggc gagaagggcg ctttgttgag gcggacggcg gcacgctgtt
    26701 tctcgatgag attggcgata tctcgccgat gatgcaggtt cgtctgctgc gtgcgattca
    26761 ggagcgcgaa gtgcaacgtg tcggcagcaa ccagactatc tcggttgatg tccggctgat
    26821 tgcggcgacc catcgcgatc ttgccgcaga ggtgaatgcc gggcgttttc gccaggatct
    26881 ctactatcgg ctgaacgtgg tggcgattga agtaccatcg ctgcggcaac ggcgggaaga
    26941 tattcctctg ctggctggcc attttcttca gcgctttgcc gaacgtaatc gcaaggcggt
    27001 aaaaggcttt acgccccagg cgatggatct gctgattcat tacgactggc cgggaaatat
    27061 tcgtgaactg gaaaacgcgg tggaacgggc ggtggtgctg ctgaccgggg aatatatttc
    27121 cgaacgcgag ctgccgctgg cgattgccag tacgccgatc ccgctggtac aaagtcagga
    27181 tattcagccg ctggtggaag tcgaaaaaga ggtgattctg gcggcgctgg agaaaacggg
    27241 cggcaacaaa accgaagccg cccgccagtt agggatcacg cgcaaaacgc tattggcaaa
    27301 actgtcgcgt tagttctgct cgcgttcgat agcgcgccag ccgatatctt tccggcagaa
    27361 gcagtcgtcc caatggatat cggtcattaa ggcataagcg cgtttctgcg cttctgccac
    27421 ggtatgaccc agcgcggtaa cgcacagtac gcgcccgccg ctggtcacta cctgctcgtc
    27481 atccgccagt ttcgtgcccg cgtggaacac tttgccgtct gccacttctt ccagcggcag
    27541 gccgtggatc acatcgccgg tgcggtaatc gcccggatat ccacccgcag ccatcaccac
    27601 gccgagagaa gcgcgttcat cccactcgga cgttttctcg tccagcttgc cttcacaggc
    27661 cgccaggcag agctcaacca gatcggactt catgcgcagc ataatcggct gggtttccgg
    27721 atcgccaaag cggcagttaa attcaataac ctttggatta ccctgtttgt cgatcatcag
    27781 gcccgcatag agaaaaccgg tgtaggtgtt gccttccgcc gccatgcctt tcacggttgg
    27841 ccagatgata cgttccatgg tgcgctgatg aacttcatcg gtcactaccg gcgcaggaga
    27901 gtaagccccc attccgccgg tgtttggccc ggtatcttta tcgcctacgc gtttgtgatc
    27961 ctggctggtg gccatcggta gcacatgctc gccgtccacc atcacgataa agctcgcttc
    28021 ttcaccgtcg aggaactctt cgataacaat acgatgaccc gcgtcgccaa acgcgttgcc
    28081 cgccagcata tcgtgaacag ctgcttcagc ttcttccagc gtcatcgcca cgataacgcc
    28141 tttcccggct gccagaccgt cagctttaat gacgattggc gcgcctttct cacgcagata
    28201 tgccagcgca ggttctacct cggtgaagtt ctggtattcc gctgtgggaa tgttatggcg
    28261 ggccagaaag tctttggtga atgctttaga accttccagt tgtgcagcac ctgcggttgg
    28321 gccgaagatt ttcagcccgg cggcgcggaa ggtatcgact acgcctttca ccagcggcgc
    28381 ttccgggccg acgatggtta gatctacctt ttcgttttgt gcgaaatcca gcagcgccgg
    28441 gatatcggtt acgccgatag cgacgttctg tagcgcgggt tccagcgcag tgcctgcatt
    28501 gcccggagca acaaaaacag tttcaaccag cggcgactga gccgctttcc aggccagcgc
    28561 gtgctcgcgc ccgccgttac cgatcactaa tactttcatc tgtcgctcca ttaatggcgg
    28621 aagtggcgca tgtcggtgaa gagcatcgca ataccgtgct cgtcggcggc ggcaattact
    28681 tcgtcatcac ggatagaacc gccaggctgg attacgcagg tcacgcccgc agcggctgcg
    28741 gcatcaatac cgtcgcggaa cgggaagaac gcgtcagaag ccattgacga acctttcact
    28801 tccaaacctt catcggcagc tttaataccg gcgattttcg cggagtacac gcggctcatc
    28861 tggcctgcgc caataccgat ggtcatattg tttttggcat agacgatagc gttggatttc
    28921 acgaacttcg ccactttcca gcagaacagc gcatcacgaa gttcctgttc agtcggctga
    28981 cgtttggtga cgacgcgcag ttcttccgca ccgaccatcc ccagatcgcg atcctgaacc
    29041 agtagaccgc cgttcacgcg tttgaaatca agacccggaa tacgttcgcc ccactgaccg
    29101 caggtcagaa cgcgtacgtt ctgcttggcg gcggtgattt tcagggcttc ttcgctggcg
    29161 gacggcgcaa taatcacttc gacgaactga cgagaaatga tggcctgcgc ggtttcagca
    29221 tccagttcgc ggttaaaggc aatgatgccg ccgaatgcgg aggttgggtc ggttttgtac
    29281 gcgcgatcgt aagcatcaag aatggaattg ccgatagcca cgccgcaagg gttggcgtgc
    29341 ttcacaatca cacatgccgg ctcggcgaac tctttcacgc actccagcgc cgcatcggta
    29401 tcggcgatgt tgttataaga gagagcttta ccctgaacct gggttgcggt agcaacggag
    29461 gcttctttca cattctcttc tatatagaag gcagcctgct ggtggctgtt ctcgccgtaa
    29521 cgcatatcct gcttcttaat gaagttcagg ttcagcgtgc gtgggaagcg accggcggct
    29581 tctttgcttt caccgtggta agccggaacc atgctgccga agtagttggc aatcatgctg
    29641 tcgtaggcgg cagtgtgttc gaaggctttg atggcgaggt cgaaacgggt tgcaagcgtc
    29701 agcgatcctt cgttggcatc catctcttta ataatggcgt cgtagtcgct gctcttcacc
    29761 acgattgcga catctttatg gttcttggcg gcggagcgca ccatcgttgg gccgccgata
    29821 tcgatgttct ctaccgcatc ttccagcgag cagccttcac gagcgacggt ctgggcgaac
    29881 ggatacaggt taacaaccac catatcgata ggctggatct gatgttcttc cataatggca
    29941 tcgtcctggc cgcgacggcc cagaatgcca ccatgtactt tcggatgcag ggtcttcacg
    30001 cgtccatcca tcatctccgg gaaaccggtg taatcggaaa cttcggttac cggcagacat
    30061 ttttctgcta acagacgggc agtgccccct gtagacagca gctccacacc gcgtgcggaa
    30121 agtgcctggg cgaattcgac gataccggct ttgtcagaaa cactgagcag agcgcggcgg
    30181 actggacgac gttgttgcat ggtaaatccc ctggatttga ctattacaga gagcgttagc
    30241 tgaatttttc gcgaaaaact cagctaacgc ccctaacggg gcatccttat ttttcgcccg
    30301 cattgtaacg aaaacgtttg cgcaacgctc gcgaattttt ctctttcaat ggtgatcaca
    30361 attttgacag tggctaccgt gggaaaaata cagaaattac attgatgatt gtggataact
    30421 ctgtgtgtaa aaaggtataa agcggggttt tgctggggaa tgcagcagtc agtcattttt
    30481 ctgcaatttt tctattgcgg cctgcggag
//
LOCUS       DAPOXO010000063        30130 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.063, whole genome shotgun sequence.
ACCESSION   DAPOXO010000063 DAPOXO010000000
VERSION     DAPOXO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30130
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.063"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            119..403
                     /locus_tag="ROH59_003266"
     CDS             119..403
                     /locus_tag="ROH59_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013263793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CbiX"
                     /protein_id="HDX4805711.1"
                     /translation="MYHYLVFVPLALIISAAALALPWFIVRAGYRELVQITCACVSVL
                     GLCAATGVFSYFDNKPLAFLYGCGALACFLYAVDCAIPLYMTRKKPRKQL"
     gene            613..945
                     /locus_tag="ROH59_003267"
     CDS             613..945
                     /locus_tag="ROH59_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805712.1"
                     /translation="MDYQTRLNSDITKEIDYLASLRKQRMVADLRTELVYGTLVRLAD
                     MICNTVTDWSLPCPVLPLSSVQQWHKAREIVLADYEDFGHAAWDYARHHMKTELSFGY
                     ACYKNDIA"
     gene            988..1188
                     /locus_tag="ROH59_003268"
     CDS             988..1188
                     /locus_tag="ROH59_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020323376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805713.1"
                     /translation="MEYGKLAAQIGMRLKLEVMESARGYYIGTQTEYGEPVSRESNEY
                     FDTEQQAEAALAGRLWTQKQNP"
     gene            1309..1578
                     /locus_tag="ROH59_003269"
     CDS             1309..1578
                     /locus_tag="ROH59_003269"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805714.1"
                     /translation="MLRIEPVPVSPRLRGQRPLTPPACGLRAPLGLRALPSALALGGW
                     RQRQPGSPVSQLPGHEAVPLAWVVPPMTAVKPGAAGCQQTLRSSC"
     gene            2527..2706
                     /locus_tag="ROH59_003270"
     CDS             2527..2706
                     /locus_tag="ROH59_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CbiX"
                     /protein_id="HDX4805715.1"
                     /translation="MTTVTTPSQLKKEVESQKELLLRACLEAFNQLPNQRLQGAFPST
                     YALAAKLDQLLQQTK"
     gene            2761..3081
                     /locus_tag="ROH59_003271"
     CDS             2761..3081
                     /locus_tag="ROH59_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000211832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcgAII protein"
                     /protein_id="HDX4805716.1"
                     /translation="MTTQTLEQTLEDFRRQCESFAREQQPRCGLIYELYQRRLSADID
                     GYLAGVPAEYREELIAVARREFDYLTQDEIAEEIRQDRENGYCSHGIERNCCPLGCGD
                     LDDY"
     gene            complement(3196..3429)
                     /locus_tag="ROH59_003272"
     CDS             complement(3196..3429)
                     /locus_tag="ROH59_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805717.1"
                     /translation="MLQELCRVRRPGRTPYSTNEFFQLLLIRNWQQWQEQKAQLGKCQ
                     ACGKLKAEGGCGGERKGETFNCWLAVEANELNL"
     gene            complement(3740..4108)
                     /locus_tag="ROH59_003273"
     CDS             complement(3740..4108)
                     /locus_tag="ROH59_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StbC"
                     /protein_id="HDX4805718.1"
                     /translation="MEKQPDKLEVLMDWFLGDAKEITATQKEMTQKLSELSEKLAKDT
                     ESLGETADSLKRALVENQRSISLAISDDAKAREEFLTKFRRAQASSAETFTRQILFIT
                     AGCTIVGAAVGAAIAILLLR"
     gene            complement(4110..4826)
                     /locus_tag="ROH59_003274"
     CDS             complement(4110..4826)
                     /locus_tag="ROH59_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="StdB protein"
                     /protein_id="HDX4805719.1"
                     /translation="MKVAVINYSGSVGKTLISSYLLAPRLTGAKFYAVETINQSASDL
                     GIEDVTSFKGDDFSRLIEDIVFEDAGIIDIGASNVEAFLMAMSRFDSGANEFDKYVIP
                     VTPDNKAIDESLKTAHTLSKAGVSSKKIIFVPNRISPDSEVEDVLAPVFEFVKETKIG
                     KISKKAVIYNSEVFEYLAFHRISFEVLTAEDPEEFKSRAKQTTDADERKKLARRYTYM
                     KQAIPVKANLDKAYAALMGE"
     repeat_region   4955..5075
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4955..4975
                     /rpt_unit_seq="ttgtgtattgtgcaatacact"
     gene            5792..6208
                     /locus_tag="ROH59_003275"
     CDS             5792..6208
                     /locus_tag="ROH59_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="traK protein"
                     /protein_id="HDX4805720.1"
                     /translation="MPTITAKVSDELLAYIDRVSGGNRSEYLRRCLEAGPGDRESGLK
                     IVADQLSDVNRKLDYLFDRASDADFGSLRDELKAITETLSGVKFPPAGQMMLHESLAI
                     ETLILLRSIAEPGKTKAAKAEVERNGYKVWEPKKER"
     gene            6210..7739
                     /locus_tag="ROH59_003276"
     CDS             6210..7739
                     /locus_tag="ROH59_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system DNA-binding
                     domain-containing protein"
                     /protein_id="HDX4805721.1"
                     /translation="MDDRERGLAFLFAITLPPVMVWFLVAKFTYGIDPSTAKYLIPYL
                     VKNTFSLWPLWSALIAGWFIGIGGLIAFIIYDKSRVFKGERFKKIYRGTELVRARTLA
                     DKTRERGVNQLTVANIPIPTYAENLHFSIAGTTGTGKTTIFNELLFKSIIRGGKNIAL
                     DPNGGFLKNFYRPGDVILNAYDKRTEGWVFFNEIRRSYDYERLVNSIVQESPDMATEE
                     WFGYGRLIFSEVSKKLHSLYSTVTMEEVIHWACNVDQKKLKEFLIGTPAEAIFSGSEK
                     AVGSARFVLSKNLAPHLKMPEGNFSLRDWLDDGKPGTLFITWQEEMKRSLNPLISCWL
                     DSIFSIVLGMGEKESRINVFIDELESLQFLPNLNDALTKGRKSGLCVYAGYQTYSQLV
                     KVYGRDMAQTILANMRSNIVLGGSRLGDETLDQMSRSLGEIEGEVERKESDPQKPWIV
                     RKRRDVKVVRAVTPTEISMLPNLTGYLALPGDMPVAKFKAKHVKYHRKNPVPGIELRE
                     I"
     gene            7739..10975
                     /locus_tag="ROH59_003277"
     CDS             7739..10975
                     /locus_tag="ROH59_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative relaxase"
                     /protein_id="HDX4805722.1"
                     /translation="MLDITTITRQNVTSVVGYYSDAKDDYYSKDSSFTSWQGTGAEAL
                     GLSGDVESARFKELLVGEIDTFTHMQRHVGDAKKERLGYDLTFSAPKGVSMQALIHGD
                     KTIIEAHEKAVAAAVREAEKLAQARTTRQGKSVTQNTNNLVVATFRHETSRALDPDLH
                     THAFVMNMTQREDGQWRALKNDELMRNKMHLGDVYKQELALELTKAGYELRYNSKNNT
                     FDMAHFSDEQIRAFSRRSEQIEKGLAAMGLTRETADAQTKSRVSMATREKKTEHSREE
                     IHQEWASRAKTLGIDFDNREWQGHGKPLEADIARNMAPDFTSPEVKADRAIQFAVKSL
                     SERDASFERQKLIQIANKQVLGHATMADVEKAYLKAVQKGAIIEGEARYQSTLKVGAS
                     VMAETLTRKEWIDSLTNSGMRADKARFAVDDGIKSGRLKKTSHRVTTVEGIRLERSIL
                     TIESRGRGQMPRQLTAEIAGQLLAGKTLKQEQMRAVTEIVTSKDRFVAAHGYAGTGKS
                     YMTMAAKELLESQGLKVTALAPYGTQKKALEDDGLPARTVAAFLKAKDKKLDEKSVVF
                     IDEAGVIPARQMKQLMEVIEKHNARAVFLGDTSQTKAVEAGKPFEQLIKAGMQTSYMK
                     DIQRQKNEVLLEAVKYAAEGNAARALKNITGVNELKEEAPRLAQLADRYLSLSSEQQD
                     ATLIISGTNASRKTLNDYIRGNLGLAGTGETFTLLDRVDSTQAERRDSRYFSKGQIII
                     PEQDYKNGMKRGESYQVLDTGPGNKLTVESSSGEQIAFSPRTHTKLSVYQAVSAELAP
                     GDKVMVTRNDKTLDVANGDRFTVKTVEGEKLTLEDKKGRTVELDKKQASYLSYAYATT
                     VHKSQGLTCDRVLFNIDTKSLTTSKDVFYVGISRARHEVEIFTDDKKSLASSVSRDSP
                     KTTAAEIDRFFGLEARFKDIGRDTSLETRSAEKGLPEATGESMAFNQKPDEHNMTTGT
                     DYQPVSNAEDAFHLKQNPMDDSVGLRRHEAQQNDAELAHDYAAADDQQWSAQEYADYE
                     HYAEASDYDFDSSIYDDYAMPQTSQAEQSHTGKEHTHEHEHEEGGHEI"
     gene            10975..11319
                     /locus_tag="ROH59_003278"
                     /pseudo
     CDS             10975..11319
                     /locus_tag="ROH59_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561167.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FipA"
     gene            11473..11601
                     /locus_tag="ROH59_003279"
     CDS             11473..11601
                     /locus_tag="ROH59_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805723.1"
                     /translation="MRYLLDIVSTDGYYWYMSGKICERVSDYRTAAFFEIGRLLTL"
     gene            complement(11775..12308)
                     /locus_tag="ROH59_003280"
     CDS             complement(11775..12308)
                     /locus_tag="ROH59_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HDX4805724.1"
                     /translation="MKKLATWLLAATFTTAALPAFAVEPSVQVGYSPEGSARVLVLSA
                     IDSAKTSIRMMAYSFTAPDIMKALVAAKKRGVDVKIVVDERGNTGRASIAAMNYIANS
                     GIPLRTDSDFPIQHDKVIIVDNVTVETGSFNFTKAAETKNSENAVVIWNMPKLAESFL
                     EHWQDRWNRGRDYRSSY"
     gene            complement(12308..13303)
                     /gene="tadA"
                     /locus_tag="ROH59_003281"
     CDS             complement(12308..13303)
                     /gene="tadA"
                     /locus_tag="ROH59_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDX4805725.1"
                     /translation="MTDAAFYQLGPLREYLEDPTVFEIRINRFQEVICDTFSGRRVVQ
                     NAAITADFIRNLAKSLVSSNKLTMQAINDVILPGGIRGVICLPPAVIDGTTAVAFRKD
                     LAADKNLEQLTSEGIFSDCRKITGSKQSLTDDDFFLKELHSSEKWPAFLQTAVEKKRT
                     IVICGETGSGKTVLTRALLKSLHKDERVIILEDVHEVTVDHVVEAVYMMYGDAGKIGR
                     VSATDALRACMRLTPGRIIMTELRDDAAWDYLKALNTGHPGGVMSTHANSARDAFNRI
                     GLLIKATPIGRMLDMSDIMRMLYSTIDVVVHMEKRKIKEIYFDPEYKMQCVNGSL"
     gene            complement(13345..14505)
                     /gene="virB10"
                     /locus_tag="ROH59_003282"
     CDS             complement(13345..14505)
                     /gene="virB10"
                     /locus_tag="ROH59_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein VirB10"
                     /protein_id="HDX4805726.1"
                     /translation="MARKSVDVDQELDGNTGDDEFESERGGFKGSNRRSAPGMKAFVI
                     LMALLALVFIGITVMGKIRAPAKAEADKDGGKAQQANTLPNYSFNSDPDVNKPVTAQN
                     SATDARAVQAAAQADADAGSSNTGARTSNKRKEPSPEELAMQRRLGGELAQTNQAATS
                     NSPGVQPQDNETSEGSSALAKNLTPARLKASRAGVLANPSLTVPKGKMIPCGTGTELD
                     TTVPGQVSCRVSQDVYSADGLVRLIDKGSWVDGQITGGIKDGQARVFVLWERIRNDQD
                     GTIVNIDSAGTNSLGSAGIPGQVDTHIWERLRGAALISVFSDVLTALVNQTQSNNIQY
                     NNTENSGEQLASEALRSYMSIPPTLYDQQGDAVSIFVSRDLDFSSVYTLADN"
     gene            complement(14505..15389)
                     /locus_tag="ROH59_003283"
     CDS             complement(14505..15389)
                     /locus_tag="ROH59_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="HDX4805727.1"
                     /translation="MKKLLLSAVVLSVLGGAATNVMALEVGRNSPYDYRIKSVVYNPV
                     NVVKIDAIAGVATHIVVAPDETYITHAFGDSESWTFAHKMNHFFVKPKQAMSDTNLVI
                     VTDKRTYNIVLHFIGEETKKNADGTVSKSFIETPWAVRQAVLQLTYEYPFEQQEKAKS
                     AADKKRITQKLKQTAFAGAKNYQYVMSEQPEMRSIQPVHVWDNYRFTRFEFPANAELP
                     QVYMISASGKETLPNSHVVGENRNIIEVETVAKEWRIRLGDKVVGVRNNNFAPGAGAV
                     ATGTASPDVRRVQIGEDN"
     gene            complement(15400..16098)
                     /locus_tag="ROH59_003284"
     CDS             complement(15400..16098)
                     /locus_tag="ROH59_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004216210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDX4805728.1"
                     /translation="MRANKKTGLTREAIKEFNESRKGLEVDLMDEVLKSRRTAWMVAT
                     GSAVVTVFALSLVGYVVHKYSQPIPAHLLTLNEATHEVQQVKLTRDQTSYGDEIDKFW
                     LTQYVIHRESYDFYSVQVDYTAVGLMSTPNVAESYQSKFKGRNGLDKVLGDSETTRVK
                     INSVILDKPHGVATIRFTTVRRVRSNPVDDQPQRWIAIMGYEYKSLAMNAEQRYVNPL
                     GFRVTSYRVNPEVN"
     gene            complement(16088..16234)
                     /locus_tag="ROH59_003285"
     CDS             complement(16088..16234)
                     /locus_tag="ROH59_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraN"
                     /protein_id="HDX4805729.1"
                     /translation="MRSLLLMGVLLISACSSGHKPPPEPDWSNTVPVNKTIPVDTQGG
                     ANES"
     gene            complement(16317..17357)
                     /locus_tag="ROH59_003286"
     CDS             complement(16317..17357)
                     /locus_tag="ROH59_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDX4805730.1"
                     /translation="MAFTLVADIFAKVDGAITSMVSANVATIISDVTPLIATCLTIKL
                     MVQGMYSAFNPGAGDSLSSLIKEYLSIALILSFATAGGWYQQELVNVALHLPDDFAGI
                     LSAPNKVGASGVPAIIDSGIEKGIKIVNTAWEAADVFSSSGLAAYAIGGIMMIATVVL
                     GGLGAGFVIMAKILLAVTLCFGPIAIFCLLWGATKNIFARWLASVINYGLVVVILALV
                     FGFIMQMFDNLLSSMNSDAAYSSITGSIAALLLTVISVFVLFQIPQIAASWGSGISAG
                     VADAARSTGSSMQALGNMGSHGMFGGNAFRGGNSGGGQQSAGGGSGSNSGGNSGSNLS
                     GKARGSRGKKAA"
     gene            complement(17373..17600)
                     /gene="eexN"
                     /locus_tag="ROH59_003287"
     CDS             complement(17373..17600)
                     /gene="eexN"
                     /locus_tag="ROH59_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncN-type entry exclusion lipoprotein EexN"
                     /protein_id="HDX4805731.1"
                     /translation="MKKLLLVIPFLLVACDASHDVEWYKKHEKERKATIQECKKDADE
                     LQKPDCKNAREADRQLFVFGKKDGEINSPKI"
     gene            complement(17608..18321)
                     /locus_tag="ROH59_003288"
     CDS             complement(17608..18321)
                     /locus_tag="ROH59_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDX4805732.1"
                     /translation="MKKTLTAVLLTTGLILGGAQSASAGIIVTNPTELAKQVEQLQQM
                     AQQLEQLKSQLQTQKNMYESMAKTTDLGDLLGTSTSTLANNLPDNWKEIYSDAMNSSS
                     SVTPSVNSMMGQFNAEVDDMTPSEAITYMNKKLAEKGAYDRVMAEKAYNNQMQELTDM
                     QELTEQIKTTPDLKSIADLQARIQTSQGAIQGEQAKLNLMNMLQQSQDKLLRAQKERA
                     THNFVFGTGGDVTASPSIN"
     gene            complement(18339..20939)
                     /locus_tag="ROH59_003289"
     CDS             complement(18339..20939)
                     /locus_tag="ROH59_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="HDX4805733.1"
                     /translation="MRAATATKPKKIDAFRKEPSVNKKYLPYSYHLNDYVISMENGDL
                     MAFFKLDGRTHDCASDRELVTWHKDLNTLVKSFGTDQVELWTHEYHHEAKEYPDGEYD
                     QFFPAYVDQYNRKLHGDSKQLINDLYLTVIYKQVGDQTQKFLAKFEKPTRDQIQQMQN
                     EALEGLEDVSEQILEAMKPYGIQQLGIYYRDKRGVEIPAPDKKEREELAEVDESDVFD
                     EAVVIERNEPEPSQAHAYSKALEFLYFLANMEWAIVPVCRERIREYIMDNRPVSSLWG
                     DVVQIRTVDHNFYTTGIEFRDYEEDTEPGQLNMLKEADFEYLLTQSFSCLSESSAKTF
                     LTHQEKSLQETRDRAQSQLAQLGTALDMLTSREFVMGYHHGTVHVWDNDQNAVQRKAR
                     RVKVMLTGCGVVGGTISLASEAAYYAKLPGNQKWAPRPVPVNSWNFLHFSSFHNFMRG
                     KPDNNPWGPALTMFRTISGTPLYFNFHVTPLEELSYGKRPLGHALITGMSGEGKTTLL
                     NFLLAQSMKYNPRLFVYDRDRGMEPFIRSVGGYYKVLQQGMPSGFAPLQIEPTKRNIA
                     LIKNLFRICVETTNNGPISATMATELAEGVDAVMGEGSLIPREARTVTILDGYVNEVV
                     ENGVSLKGLLREWTREGQYGWLFDNDKDSLDLSTNDIFGFDLSEFIAAKEEVSSPART
                     PLMMYLLYRVRDSIDGKRRVIQCFDEFHAYLDDPVIEREVKRGIKTDRKKDAIYVFAT
                     QEPNDALSSRIGRTIMSQTVTKICLRDPEAIREDYAFLTDAEYDALMSITEHSRQFLV
                     KQGQQSAIASFNLYPRNSDDIDADIKTMDNVLSVLSGEPQNAEIAHELVERLGNDPEV
                     WLKEYWRLTA"
     gene            complement(20939..21256)
                     /locus_tag="ROH59_003290"
     CDS             complement(20939..21256)
                     /locus_tag="ROH59_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000496058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="HDX4805734.1"
                     /translation="MFVDGKRPLFKGATRLPRALGVPRNVAMLIFMISASLFMIIHMW
                     AILVFVFLWIPSAALTKYDDRMFRIMGLWLKTKFSNWFDSPFKQWGGSSYSTADYKRK
                     GLK"
     gene            complement(21306..21599)
                     /locus_tag="ROH59_003291"
     CDS             complement(21306..21599)
                     /locus_tag="ROH59_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraM"
                     /protein_id="HDX4805735.1"
                     /translation="MTTLFKKYGPAVVMGVLSIALPQIALAAGTDTGESTATSIQTWL
                     NTWIPLGCAIAIMVSCFMWMLHVIPASFIPRIVIALIGIGSASYLVSLTGVGS"
     gene            complement(21609..21890)
                     /locus_tag="ROH59_003292"
     CDS             complement(21609..21890)
                     /locus_tag="ROH59_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX4805736.1"
                     /translation="MERLYLVLQSQILELFEAGKVKEVTIERVSLKKWYPVFQIDDEQ
                     LGQIACSIRVNKEHELRTWADLRLLAEFLKDKCGVEECRLNLKSTEDSE"
     gene            complement(21899..22633)
                     /locus_tag="ROH59_003293"
     CDS             complement(21899..22633)
                     /locus_tag="ROH59_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDX4805737.1"
                     /translation="MSKHPKLLVLALACLACAGRASAAPASDEIARLAQRCAPDVSPL
                     TMAYIVGHESSNGPYRININGSTQLKQQPRTEAEAVSVAKVLLKDNKSFDMGLAQINS
                     NNLVGLGLSVDDIFKPCINLRASQTILKACYDSALKSYPAGQVALRHALSCYNTGSLT
                     NGISNGYVTKVINVARQSTDLKIPTLLPDGQTSEDSTATEPQQAKSTAPQYDGEQDVF
                     GSGDGDAFSRNNTDAFLTKQETAKGE"
     gene            22697..23047
                     /locus_tag="ROH59_003294"
     CDS             22697..23047
                     /locus_tag="ROH59_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000960954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS histone family protein"
                     /protein_id="HDX4805738.1"
                     /translation="MSRRNEKKTAEGRKVMLVPLKSEKRPKGEPVYRDPDNPFNTWTG
                     IGKRPAWLTAKLDAGISLEAMKMQGVANPREHRPAKYRDPRNAENTWSGTGRRPTWLK
                     ELLDSGLSLDDLKI"
     gene            23063..23407
                     /locus_tag="ROH59_003295"
     CDS             23063..23407
                     /locus_tag="ROH59_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805739.1"
                     /translation="MGEIIDFAERQKGRRKKKASSIPPILRKFRVHAIRLLASIIKSG
                     SYSVAYIVKKITGKLIKFFTILTIFVFVVEYIAGDIGYKSIYNAALLLMLLTVINILA
                     GVYLNKLLRTKQ"
     gene            23404..23718
                     /locus_tag="ROH59_003296"
     CDS             23404..23718
                     /locus_tag="ROH59_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncN plasmid KikA protein"
                     /protein_id="HDX4805740.1"
                     /translation="MKKLLIPLIAAGSLLYLPASHAEDPCKVIMCMAGKLTGDSGGSE
                     CNSAEAAFFNIVKKNKHGFLPNHTKDARKAFLNECPDNGEGGSNQSMISQIISKYGKV
                     RL"
     gene            23754..24065
                     /locus_tag="ROH59_003297"
     CDS             23754..24065
                     /locus_tag="ROH59_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001452736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805741.1"
                     /translation="MKKIILSALACTALLTGCVSQDKGNAMQSQLNNQQRQINELSVR
                     LQSAESRLSKQEEKLRNELLQSSGYCYLNGARYSTGTVLYGRICQNQSGSASWQVYSR
                     R"
     gene            24274..24762
                     /locus_tag="ROH59_003298"
     CDS             24274..24762
                     /locus_tag="ROH59_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001452734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HDX4805742.1"
                     /translation="MPGFPQKINYLRKIDPFVFEELLLEGFEAHGFKTIRNKRYTGDG
                     GIDGQVIIGKYRYLIQAKRYRGHIALQHVQEFDNLLKRHNCRGLFCHTGKTGAGSKSV
                     SIASDRMEIISGQRLIDLLTPGSSFTIATAPQTMMKRTAATRVTNTIVKDAGNENRYH
                     ES"
     gene            24767..24967
                     /locus_tag="ROH59_003299"
                     /pseudo
     CDS             24767..24967
                     /locus_tag="ROH59_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749967.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24986..25168
                     /locus_tag="ROH59_003300"
     CDS             24986..25168
                     /locus_tag="ROH59_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002208622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805743.1"
                     /translation="MRFRRCSSLDTLEKVFESLREKLSGKELDAMMSASDHRRAEITH
                     NTLWDKVPASAWRNVK"
     gene            complement(25195..25632)
                     /locus_tag="ROH59_003301"
     CDS             complement(25195..25632)
                     /locus_tag="ROH59_003301"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805744.1"
                     /translation="MAISELSLGKQILDKINNHDVYNSRLRLKIQLSNIVGFVVLFMI
                     GSKFNQLILCSIAFVIVFVLTNIFWRFKSAISSSLLFDYFERSADDDGFREFFMGLFN
                     SKDLLTVRDDRVKISHFLYEQDKRYDELKKIETITNGMKGRGE"
     gene            complement(25641..25967)
                     /gene="mazF"
                     /locus_tag="ROH59_003302"
     CDS             complement(25641..25967)
                     /gene="mazF"
                     /locus_tag="ROH59_003302"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HDX4805745.1"
                     /translation="MKHDYIPDAGDIVWINFDPQAGHEQAGHRPALVLSPAIYNGKIG
                     LMLCCPMTTKIKGYPFEVRNGEGSAVLADQVKNLDWRERGAVRKGKVPPTVLAEVRAK
                     LKVLIG"
     gene            complement(25957..26214)
                     /locus_tag="ROH59_003303"
     CDS             complement(25957..26214)
                     /locus_tag="ROH59_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805746.1"
                     /translation="MLKVLKKIFSCVQFICALVVFGIGTYCIWLGFSKIFRDNSIHIG
                     GFEAVSLLDTTPFAIMFIFSGVLIIAFVWVVYISKRLNNEA"
     gene            complement(26222..26764)
                     /locus_tag="ROH59_003304"
     CDS             complement(26222..26764)
                     /locus_tag="ROH59_003304"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805747.1"
                     /translation="MKKDGRTFIRWFSFGCKSLFAVIGIGIAYYAAIGVFGLAYNPVS
                     YYFSEWVNWMQPKIKLPVTYNDSSLYLNDGTYSLGGYLMSVGYLLVMFLVQLYVAAYL
                     LNKLYWSLMTQVIIHKEGRDFHRKYAGISSARFTRLLSEAEVDMELEDISRKHWEKWR
                     EHYKSNMSYDEWKKKFKKVL"
     gene            complement(26764..27012)
                     /locus_tag="ROH59_003305"
     CDS             complement(26764..27012)
                     /locus_tag="ROH59_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HDX4805748.1"
                     /translation="MGTQVTVKKWGNSPSVRLPSAIVRAASLNVDDVVELSVEDGKIT
                     IVPVKTKEYSLDALMAGVTAENIHEEVSFGPPVGKELL"
     gene            complement(27025..27306)
                     /locus_tag="ROH59_003306"
     CDS             complement(27025..27306)
                     /locus_tag="ROH59_003306"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805749.1"
                     /translation="MLERYVQRNSAWLFPFIAGLILATAPLMLEMITDKNPLPAWAPV
                     AAACIGFCASGIGAAFTNTLSAKIIKLLVGVFAVVMVIMIVIKLVNLFH"
     gene            27524..28243
                     /locus_tag="ROH59_003307"
     CDS             27524..28243
                     /locus_tag="ROH59_003307"
                     /inference="COORDINATES: protein motif:HMM:NF015487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="HDX4805750.1"
                     /translation="MSSGNFFSPAGLSAAATILLTLPGQVQASAENYQYQMKYSADAQ
                     SIRPTTVFDDGKATWFVIPSDPKSPPAILIVTPDGKEKLPVRYVTAPNADNTAITIIA
                     YDVAEEWRIRKGAMVVAVRNENFKNGVTVTDHEKKISKEEQKIHDDIAEYLTRLNTVS
                     SQVVIKMQNIDVHPENNSADFSYARFIKTTKNNAAYVNYEKIQGNLTYRYVEQRKEKN
                     GPQQKPVFQVQSIQFKTVENK"
     gene            28246..28845
                     /locus_tag="ROH59_003308"
     CDS             28246..28845
                     /locus_tag="ROH59_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDX4805751.1"
                     /translation="MIIGYARKSTHLQDVAHQVDELKKAGCEQIYQEQTSRGGPKRES
                     KGAPELENCLKALREGDTLIVWALDRLGGSLAQVITLLDDLKKRGITFIAIKDRIDTS
                     APVIGEVYTHLMAIFSAFERNRNIERTRSGLAAARARGRVGGRKPALSEEDIKQIKIL
                     LADPEMTVSLVAKRFNVSRMTIYRYTNSDNALADEAGKE"
     gene            28848..29729
                     /locus_tag="ROH59_003309"
     CDS             28848..29729
                     /locus_tag="ROH59_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020323144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDX4805752.1"
                     /translation="MAEDKPLTKQQQKTVEASAQIKQDPPKGNDLAFTHSILCQVGLP
                     RSKPEGREFMRRSGDAWLVVQAGWLDEGNGPVEQCLPYGPMPRLAMAWVSSFALRNKT
                     REIKIGSSANEFLKLLGMEPQGARHKTLRTQMHALAACRLQLGFRGRTYNGQPVEQFD
                     AWLRNEDSGQQSLWPGLLVLSDGYFKGLLESAVPLDNRALSALKGSALALDIYAWLAH
                     RLHRIEGRPVLLYWANLRDQFAQEYKGKDPDKDFKKKFLPALKDVLAVYPTAKVQQVK
                     GGILLYPSPPPIPYKIP"
     gene            complement(29779..29979)
                     /locus_tag="ROH59_003310"
     CDS             complement(29779..29979)
                     /locus_tag="ROH59_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805753.1"
                     /translation="MSVELDKISLNLELSNTEAWALAQFCKRTTHQDCVNVSTSENEA
                     YEMMDGINAIMRTLAEAGIAPR"
BASE COUNT         7811 a         7669 c         7150 g         7500 t
ORIGIN      
        1 gtaaatatat tccgtactta tattgacttt aaaggcgtaa tcaccgataa ttaaatcatc
       61 gggaggcaac accgccgccc gaacaatcgc cggtatcggc aaccatcaag gagttcacat
      121 gtatcactat ctcgtttttg tccctctcgc attaattatt agcgccgctg cgcttgccct
      181 gccctggttt atcgttcgtg cgggatacag ggaactggtg cagatcacct gcgcctgcgt
      241 ctctgttctg ggcctgtgtg cggcgacagg ggttttcagc tacttcgata ataagccgct
      301 tgcgttcctg tacggctgcg gcgcactggc gtgctttttg tacgcggtag actgcgcgat
      361 accgttgtat atgacgcgta aaaagccacg taagcagctg taagaaaaaa aggcgggtaa
      421 ttcccgcctt ttttattgag gctgtcagaa agcgattaag gcgctctatg gacgctttgc
      481 aagatataaa atcttgtata tatattccgt acttatattg actttaaggg cgtaatcacc
      541 gataattaaa tcatcgggag gcaacaccgc cgcccgcaaa attgccggta tcggcgcgca
      601 aaggagtaca tcatggatta ccagacccgc ttaaattctg acataaccaa agagattgat
      661 tatctggcat cactgcgtaa acagcgcatg gtggcggatc tgcgcacaga gctggtttac
      721 ggcacactgg tgcgtctggc agatatgatc tgcaacaccg tcactgactg gtcacttccc
      781 tgccctgttc tgccgctttc ttccgtacag caatggcaca aagcccgcga aattgtcctg
      841 gcagattatg aggacttcgg ccacgctgcc tgggactatg cccgccacca tatgaaaaca
      901 gagcttagct tcggttatgc ctgctacaaa aacgatattg cctgatgatt aacaacatgg
      961 gggctaacgc cccctgaagg agaaaagatg gaatatggaa aactggccgc tcaaatcggg
     1021 atgcgcctga aactggaagt gatggagtca gcccgcggct attacattgg aacgcagaca
     1081 gaatatggtg agccggtatc acgcgaatct aacgaatatt ttgataccga gcagcaggca
     1141 gaagccgcac tggctggcag attatggaca cagaaacaaa acccctgatc ccacaatggc
     1201 gcccaaacgg gcgccattat tcttttatgg ccataccgcc gatttcagat agaacgagag
     1261 agaaacagcg gcagactccg ggcgttaccc cttcggggcc gctctgctgt gctacgcatc
     1321 gagccggttc ccgtctcgcc ccgcttacgc gggcagcggc cgctaacgcc tccggcctgc
     1381 ggcctccgcg ctccgcttgg cctccgggct ttgccctccg cgctggcgct tggcggctgg
     1441 cgtcagcgcc agccaggttc gccggtatct cagctgcccg gtcatgaagc cgttccgttg
     1501 gcgtgggtcg ttccgcctat gaccgcagtg aaaccgggcg cggcaggttg tcaacagacg
     1561 cttcgctcaa gctgttgaca acctgcctta tccgcccggt tacaatgcgg ccgtcggaaa
     1621 cgacaccccg ccaacttctc tacaggtgct acatgacctc taccatcctc gaaaacctcc
     1681 cgcaaatcct cacctcgctg gctgctctga ttacggccgt aaccggccta atcaaagcgc
     1741 tgcgcgacaa agacaagtaa cagccatcgg ggcggctgcg ccgccccttt gctgctgctt
     1801 gccggtgatc tctccagctc atgttctgcc attgcgctaa atcctgatgc cacaccgggc
     1861 gttacccctt cggggccgct ctgctgtgct acgcatcgag ccggttcccg tctcgccccg
     1921 cttacgcggg cagcggccgc taacgcctcc ggcctacggc ctccgcgctc cgcttggcaa
     1981 gccacaccct gcgccggact cgcccggccg caagcggccg ccccgcccct tcggggtgcc
     2041 aacgcccttc aggcgtcggc atcctttgcc agtgcgctat tgtgttatct gtggattgcg
     2101 cagctcagcg gggcgctgcc cgtgacggtg cggtgtcccc cgtaaccggc cgcgtggcgg
     2161 ccgctaactc gcagtacggc gccgcgaccc gcaggcgggc cgccgtaccc gcgcgcaggc
     2221 gcgcggcgcc cactgcgcac ccccgtgggg gacgtgcggc agctgcgtgg cggcgggctg
     2281 ggttatggct tagcagggag gggggttggc ctgctgctcc ggtcaacccc gcagtttccg
     2341 gcgatttgcg gccggtgtcc ggtggagtcc ggcgcggtcg ccttccatgc cctgacgggc
     2401 ataaaaacag gtaaatatat tccgtactta tattgacttt aaaggcgtaa tcaccgataa
     2461 ttaaatcatc gggaggcaat accgccaccc gctaaattgc cggtatcgga tcactaagga
     2521 gtaagcatga ccactgttac caccccttcc cagctgaaaa aagaagtcga atctcagaaa
     2581 gaattattgc tgcgcgcctg cctcgaagcg ttcaaccagc tgcctaatca gcgcctgcaa
     2641 ggcgctttcc catcgacgta tgcactggcg gcaaaattag accagctgct gcaacaaact
     2701 aaatagcact gacgacccgg ccaagccggg tctttaacag aaagatcgag gacaaacgac
     2761 atgaccacac aaacccttga gcagactctt gaagattttc gtcgccagtg tgagagtttt
     2821 gcgcgcgaac agcagccccg ctgcggcctg atttatgaac tgtatcagcg ccgcctgagc
     2881 gcggatattg acggctatct tgctggcgtt ccggccgagt atcgggaaga actgatcgca
     2941 gtagcgcggc gtgaatttga ctatctgacc caagacgaga tcgcggaaga aatccggcag
     3001 gatcgggaaa acggttattg cagccacggt attgagcgta attgttgccc gctgggctgc
     3061 ggagatctag acgattactg agccgccgaa agaaacaagc ccggattgac cgggcttttt
     3121 tctttccgct gcgcggccgt tccagagata gccggttgtt ctttgtctct gtgtaaatat
     3181 gtattgcaca atacactaca aatttagttc gttggcttcg acggcaagcc agcagttaaa
     3241 ggtttcgcct ttccgttcac ccccgcaacc tccctccgct ttcagctttc cgcaagcctg
     3301 gcattttccc agctgtgcct tttgctcctg ccactgctgc cagttgcgga tcagcagcag
     3361 ctggaaaaat tcgttcgttg aataaggcgt tcgtccagga cggcgaaccc ggcacagctc
     3421 ctgcaacatt gcttcttcct gttttgttag cgtgactgtc acgcttgcgc cttcttcctt
     3481 gagccgcgcg cggcggcggg cctggcgtat acgggccagt tctcgctgtc ggtcattcat
     3541 tatttttctc cccgtgatgg tcacgcgtga ctgtcacgct gaattaaaac gggcattgcc
     3601 cctgcggggc cgttctgccg tgctgcgcat cgagccggtt cccgtctcgc cccgcttacg
     3661 cgggcggcgg ccactaatgc ctccggcctt cggcctccgc gctccgcttg aaaaaaaacc
     3721 gggacacgcc cggtttgctt tatctaagta ggagtatcgc tatcgcggcg cctactgcgg
     3781 cgcccacgat ggtgcagcca gctgtaataa aaaggatctg acgggtaaac gtctcagcac
     3841 tggacgcctg cgcgcggcgg aatttagtta gaaattcctc acgtgcctta gcatcatcac
     3901 taattgccag gctaattgaa cgctggtttt ctactaaagc ccgtttaaga gagtctgccg
     3961 tctctcctaa actctcggtg tcttttgcca gcttttccga aagctcagaa agtttctgcg
     4021 tcatttcttt ctgagttgcg gtgatttcct tcgcgtcacc taaaaaccag tccatcagaa
     4081 cttctaattt gtccggctgc ttttccattt tattctccca ttaaagccgc atatgcttta
     4141 tcgagattag cttttaccgg aatcgcctgt ttcatgtatg tataacggcg tgccagtttt
     4201 ttgcgctcgt cagcatcggt tgtttgtttt gcacgggatt tgaattcttc tggatcttca
     4261 gcggtcaata cttcgaatga gatacggtga aacgccagat attcgaaaac ctcactgtta
     4321 taaataacag ccttcttgct tattttgcca atcttcgttt ctttgacaaa ctcaaacacc
     4381 ggcgccagca catcttctac ttcactgtct ggactaatac ggtttggaac aaagataatt
     4441 ttcttgctgc tcacgccagc tttacttaac gtgtgtgccg ttttcaggct ttcatcaatc
     4501 gccttattat ccggcgttac cgggattaca tatttatcaa attcgttcgc gccactgtca
     4561 aagcgagaca tagccatcag gaacgcttca acgtttgacg cgccaatatc aataatccct
     4621 gcatcttcaa aaacaatatc ctcaatcaaa cgtgagaagt cgtcaccttt aaaactggtc
     4681 acatcctcaa tacccagatc ggaagcagac tggttgatag tctctaccgc atagaacttt
     4741 gcaccagtca ggcgcggggc taacaggtac gatgaaatta aggttttacc aacactgcca
     4801 ctgtaattaa ttaccgctac tttcataaat cacctcagaa ttttttgttg aacttcttag
     4861 ggtcgaaatc ctcaccgatt ttattgaaga actctttatc aataatgccg ggactctcta
     4921 ccttttcact ttcctgcgct tcaggctcag acggttgtgt attgtgcaat acactttcct
     4981 ctgtaccctt cgcgctactc ttgctttgtg tattgtgcaa tacactatcc gcatcatccg
     5041 gcttactgtc ttgtgtattg tgcaatacac ttttccggtt ttgccgcgct ctatacagtg
     5101 ccatctcaag ccctttggcc gtcaccgaaa agctgtattc gctgccgagg atttcagcaa
     5161 tttcatgccg ggttattccc ctgtccagcc agttctcgat ttcatccagg cgcaatctga
     5221 cagcagccga taagttgcgg ggtttcagat cagcaggttt attcataacc cctccgttgt
     5281 atgaagctga ctctacagca cccgtaaaat ggggtcaatg caattttgta gtttctctgt
     5341 agtttttgag tagtctatca cggaatactg tagttttttt gtagtcgatt agtagtctgc
     5401 tatcacctgt ataaagcggt ttttgtagtc tttctgtagt ttctccgtag tttctggctg
     5461 ctcagatggt catgcaagca tgaccatcaa agaataggac gctttttagc cagatagtcc
     5521 ttaacctacg gagatcgctc ctaccaaaaa agatgatttt ttatccctta acctgctata
     5581 cacctaacgc agcgtgataa atcacgctat cctactgatt taaaatcaaa aaaaaccata
     5641 tttagccata ttgtagtatt atcacggtat tacaaaatta atctaacttt atgatttata
     5701 acatgtttga tttattactt tggtaatact atgattccac cgtattagat accccttttt
     5761 tcgtttaaaa aatgcacaaa gtgagggcta aatgccaaca ataaccgcaa aagtatcaga
     5821 tgaacttttg gcctatatag accgggtttc aggcggtaat cggtcagagt atctgcggcg
     5881 ctgccttgaa gctggcccag gagatcggga gtccgggttg aaaatagttg ccgaccagct
     5941 gagcgacgta aatcgcaaat tggattacct ttttgaccgt gcttcagatg cggattttgg
     6001 ctcactgcgc gatgagctga aggcaataac cgaaacgcta tctggcgtaa aattcccacc
     6061 ggcaggacag atgatgttgc atgaatcact cgctattgaa acgctgatcc tcctgcgttc
     6121 gatagcagaa ccgggcaaaa ccaaagcggc aaaagcagag gttgaacgta acggctacaa
     6181 agtctgggaa ccaaaaaagg agcgctgaaa tggacgatag agaaagaggc ttagcatttt
     6241 tatttgcaat tactttgccg ccagtaatgg tatggtttct agttgctaaa tttacctacg
     6301 gtattgaccc atcaacggct aaatacctga taccgtatct tgttaaaaac actttttcgc
     6361 tatggccttt atggtcagct ttaattgctg gctggtttat tggtattggc ggtctgatcg
     6421 cttttatcat ttatgataaa tcacgcgtgt ttaaaggcga aagattcaaa aagatttatc
     6481 gtggtacaga gcttgttcgc gccagaacac tcgctgataa aacacgcgaa agaggtgtca
     6541 accagttaac cgtggctaat atccccatac ctacatacgc tgagaacttg catttttcga
     6601 ttgccgggac aaccggtact ggtaaaacca caattttcaa tgaactgtta tttaagagca
     6661 tcattagagg cggcaaaaat attgctttag atccaaatgg ggggttctta aagaatttct
     6721 atcgtcccgg cgatgttatt ttaaacgcct atgataaacg cactgaaggc tgggtgtttt
     6781 tcaatgaaat ccgccgttca tatgattacg agcgcttagt gaactctatt gttcaggaaa
     6841 gccctgatat ggctactgaa gaatggttcg gctatggccg tcttattttt agtgaagttt
     6901 cgaaaaaact tcacagccta tacagcacag taactatgga agaagttatt cactgggcct
     6961 gtaacgttga ccagaaaaaa ttaaaagaat ttttaatagg gacacctgct gaagctattt
     7021 tttccgggtc tgaaaaagca gttggaagcg cgcgatttgt tctcagtaag aatcttgccc
     7081 cacatttgaa aatgccggaa gggaattttt ccctgcggga ctggcttgat gatggaaagc
     7141 cgggaaccct gtttatcacc tggcaggaag aaatgaaaag gtcacttaat ccgctaattt
     7201 cctgctggct ggattcgatt ttttctatcg tcctgggtat gggggaaaaa gaaagccgca
     7261 ttaatgtatt tattgacgag ctggaatcac tccagtttct gccaaacctc aacgatgcac
     7321 tgaccaaagg gcgtaaaagc ggtctgtgtg tttatgctgg ctatcaaacc tattctcagc
     7381 tggttaaggt ttatggtcgg gatatggctc agaccattct ggctaacatg cgttctaaca
     7441 tcgtgctggg cggcagccgt ctcggtgatg aaacgttgga tcaaatgtcg cgctcactcg
     7501 gtgagataga aggcgaagtt gagcgtaaag aatccgatcc tcagaagccc tggattgtcc
     7561 gtaaacgccg cgacgttaaa gttgttcgtg ccgtaacgcc taccgaaata tctatgttgc
     7621 caaacctcac cggctatctg gcgttgcctg gtgatatgcc cgtcgctaag ttcaaggcta
     7681 aacacgttaa ataccatcgc aaaaaccctg ttcctggcat tgaactgagg gagatctgat
     7741 gcttgatata accacgatta cccgccagaa cgtcactagc gttgtgggct actactctga
     7801 tgcaaaggat gattactaca gtaaggattc atcattcacg tcctggcagg gaaccggagc
     7861 tgaagccctc ggcttatccg gggacgttga atcagcccgg tttaaagagc tgcttgtcgg
     7921 tgaaatcgat accttcacgc atatgcagcg acacgtgggt gatgccaaaa aagagcgtct
     7981 gggctacgac ctgacgtttt cagcgcctaa aggggtatcc atgcaggcgc tgatccacgg
     8041 cgacaaaacc attatcgagg ctcatgaaaa agctgttgcc gctgccgtgc gtgaagctga
     8101 aaaactcgcg caggcccgga cgactcgcca ggggaaatca gtaacccaga ataccaataa
     8161 ccttgtcgtc gctactttcc gccacgaaac gtccagggcg cttgatcctg atctgcacac
     8221 tcacgctttt gtcatgaaca tgacccagcg cgaggacggc cagtggcgcg cgctcaaaaa
     8281 tgacgagctg atgcgtaaca aaatgcacct gggcgatgtt tacaaacagg agctggcgct
     8341 ggagttgacc aaagccggtt atgagctgcg ttacaacagc aaaaataaca cgttcgatat
     8401 ggcccatttt tcagacgaac agatccgcgc tttctcccgc cggtcggagc aaattgaaaa
     8461 gggactcgct gcaatgggcc tgacgcggga aaccgccgat gctcagacga aaagccgcgt
     8521 ctcgatggcg acgcgtgaaa agaaaacaga gcattcccgt gaagaaattc accaggaatg
     8581 ggccagccgc gccaaaacgc tcggcattga ttttgataac cgtgaatggc agggacacgg
     8641 taaacctctg gaggctgata ttgcgcgcaa catggccccg gattttacca gcccggaggt
     8701 taaagctgac cgggctatcc agtttgcagt taagtcgctg tcagagcgcg atgccagctt
     8761 tgaacgccag aagctgattc agatcgctaa taagcaggtg ctgggccatg ccacaatggc
     8821 cgatgttgaa aaagcgtacc tgaaggcggt acagaaaggc gccatcatcg agggcgaagc
     8881 ccggtatcaa tcaacgctga aggtcggtgc ttcagttatg gccgaaactc tgacgcgcaa
     8941 agagtggatc gactcgctga cgaatagcgg gatgcgcgcg gataaagccc gttttgcggt
     9001 agatgatggt attaaaagcg gcaggctaaa aaaaaccagc caccgcgtca ctaccgttga
     9061 gggtattcgc cttgagcgtt ccattctgac tatcgaatca cgcggccggg ggcagatgcc
     9121 gcgacagctg accgcagaga ttgcaggcca gttgctcgcc gggaaaaccc tcaaacagga
     9181 acaaatgcgc gcggttactg aaatagtgac aagcaaggat cggtttgtgg ccgcacatgg
     9241 ttacgccggt accggtaaaa gctatatgac gatggccgct aaggagctgc tggagtcaca
     9301 agggctgaag gtcacggcgc tggcccccta tgggacgcag aaaaaagcgc ttgaagatga
     9361 tggattaccg gcccgcaccg ttgccgcctt cctcaaagca aaggataaaa agctggatga
     9421 aaaatcagtc gtattcattg atgaagccgg ggttataccc gcgcggcaga tgaaacagct
     9481 gatggaggtt atcgagaaac ataatgcccg cgcggtattc ctgggggata cgtcacaaac
     9541 gaaagcggta gaagccggta agccttttga gcagctgatt aaagcaggta tgcagaccag
     9601 ctacatgaaa gacattcagc gacagaagaa tgaagttttg cttgaggcgg ttaagtatgc
     9661 cgctgaaggt aatgccgcgc gcgccctgaa aaatatcacc ggcgtgaacg aactgaagga
     9721 agaagcgccc cgactcgctc aacttgccga tcgctacctg tctctgtcct cagaacaaca
     9781 ggatgccacc ctgataatct ctggtacgaa cgcctcacgc aaaaccctca atgactacat
     9841 ccggggcaat ctggggcttg ccggaaccgg cgaaacgttc acgctacttg accgcgtgga
     9901 ttcgacacag gcggaacgcc gcgacagccg ttatttcagt aaagggcaaa tcattatccc
     9961 cgaacaggat tacaaaaatg gtatgaagcg gggcgagtct taccaggttc ttgataccgg
    10021 gccgggcaac aaattgacgg ttgaaagcag cagcggtgag cagatcgctt tcagcccgcg
    10081 tacacacacc aagctgtctg tataccaggc agtcagcgcc gaactggcgc cgggcgataa
    10141 ggtcatggta acgcgtaacg ataaaacgct ggacgttgcc aacggcgacc gcttcacggt
    10201 gaaaaccgtg gagggtgaaa aactgacgct tgaggacaaa aaagggcgca cggttgagct
    10261 ggacaaaaaa caggcttctt atctttccta tgcttatgca accaccgtcc acaaatccca
    10321 gggacttacc tgtgatcgcg tgttgttcaa catagatacc aaatcgctta ccacttctaa
    10381 ggacgttttt tatgttggta tttcgcgtgc gcgtcatgag gtggaaattt ttaccgacga
    10441 taaaaaatct ttggcatcga gcgtgagccg cgacagcccg aaaaccacgg ccgcagaaat
    10501 tgaccgtttc tttgggcttg aggctaggtt taaggatatt ggccgcgata ccagtttaga
    10561 aacccgatca gctgaaaaag gtctgccaga agccacgggg gaaagcatgg cgtttaacca
    10621 gaaacccgat gaacataaca tgacaaccgg cactgattat cagccggtga gcaacgcaga
    10681 ggacgccttt catcttaagc agaaccctat ggatgattcc gttggcctgc ggcgtcatga
    10741 agcacagcaa aatgatgcag agctggccca tgattatgct gctgccgacg atcagcagtg
    10801 gagcgcgcag gagtatgccg attacgagca ttatgccgaa gcatcagact acgactttga
    10861 cagcagcatt tacgacgatt acgccatgcc gcagacgtct caggcggaac agagccatac
    10921 cggaaaagaa cacacccatg agcatgagca tgaagaaggg ggccatgaaa tctgatggag
    10981 cagaccgaca agcgcaagca ggataaactg aagttcgacc gggtaattaa tctggcgcgc
    11041 agactgccgc aaccggcgat ccatgactta ctacgcgcgc tgatactgcc aattcaggcc
    11101 gattacttgc tggccgttgg cacggagggc caggacgcgc gcccggacat gaacgagcgc
    11161 gagttcttct tcacaaaaat catctgggcg atggattaca cgcacatgaa atcactcagg
    11221 cttgctgctg aagattttcc cctggcgctt gcgacggcca agatcctgcc gtggccgtgg
    11281 ggtgaatcaa gctaccggag tgctttagcc gatataggca gcgctaaggg caatccgtgg
    11341 gtacaggata ttaaccaccg cgttactttg tggttgccct ggcggatagg ctttgtacga
    11401 ggagggaacc attctattgc cagcggcgtt ctggccggtg agggtgaggt aatacccgat
    11461 acggtttatg atatgcggta tttgctcgat attgtcagca ctgacgggta ttactggtac
    11521 atgagcggga agatctgcga gagagtcagt gactaccgta cagccgcctt ttttgaaata
    11581 ggccgcctgc ttacactgtg attccttcaa aatatctcaa cgaaatttcc cgacacctgt
    11641 ttaagctatc ttactgatat ttctgttttt cgatttttgc cggcgcgatg ccggcgacgt
    11701 tggccagctg ccccgggcgc gatactgaaa tcagtttctt tgaacaaaaa aaaccgcctt
    11761 tcggcggtca gtattcagta gctggaacgg tagtctcgcc cccgattcca gcggtcttgc
    11821 cagtgttcga ggaatgattc agcgagctta ggcatgttcc agatcaccac cgcattctcc
    11881 gagtttttcg tttcggccgc tttggtgaaa ttaaagctgc cagtttcaac ggtcacatta
    11941 tccacgatga tcaccttgtc atgctggata gggaaatcac tgtcagtacg caaagggatg
    12001 ccgctgttcg ctatgtagtt catagccgca atgctggcac gtcccgtatt gcccctttca
    12061 tcaaccacga tttttacatc aactccccgt tttttcgctg ctaccagtgc cttcataata
    12121 tccggggcgg taaaggaata agccatcatc cgtatcgagg tttttgcgga gtcaatggcg
    12181 ctcaggacga gaacgcgggc gcttccttca ggcgagtagc caacctgaac ggatggttcc
    12241 accgcaaagg cgggcagggc ggctgtcgta aatgttgcgg ccagaagcca ggttgctaac
    12301 tttttcatta caggctcccg ttcacacact gcattttata ttcagggtca aaataaattt
    12361 ctttgatttt ccgcttttcc atatgcacca caacgtcaat ggtggagtag agcattcgca
    12421 taatatcgct catatcgagc atacggccga taggggtcgc cttgataagc agcccaatac
    12481 ggttaaaggc atcgcgcgct gagttagcgt gcgttgacat aacaccgcct ggatggccgg
    12541 tattaagtgc tttaaggtaa tcccacgcag catcatccct aagctcggtc atgatgatac
    12601 ggcccggtgt cagacgcata caggctcgca gggcatcagt ggcgctgacg cggccgatct
    12661 ttcctgcatc gccgtacatc atataaacgg cctcgacaac gtgatcgacc gtgacttcgt
    12721 gaacgtcctc taaaataatg acgcgctcgt ctttatgtag cgattttaac agggcgcgcg
    12781 tgagtaccgt tttccccgac ccggtttcac cgcagatcac gatagtgcgt ttcttctcaa
    12841 cggcggtttg caggaatgcg ggccattttt cgctgctgtg cagctcttta aggaaaaaat
    12901 catcatccgt taggctttgc ttgctgccgg taatcttccg gcagtcactg aaaatcccct
    12961 cgctggtcag ctgctccaga tttttatctg ccgccaaatc cttacgaaac gctacggccg
    13021 ttgtaccgtc aatcaccgca gggggcagac agataactcc cctgatcccg ccaggcagga
    13081 tcacgtcatt aatggcctgc atggtcagct tgttgctgct caccaacgat ttagcaaggt
    13141 tcctaataaa atctgccgta atcgccgcgt tctgcacaac cctgcggccg ctgaacgtat
    13201 cacagataac ttcctgaaag cggttaatgc gaatttcaaa aacagtagga tcttctaaat
    13261 actcgcgcag tgggccaagt tgatagaaag ctgcatcagt catgattact cctgaagaaa
    13321 agcgggcgct aagcgcccgt ttttttagtt gtctgcgagc gtgtaaacgc tgctgaaatc
    13381 gaggtcgcgg gaaacaaaaa tgctcaccgc atcaccctgc tgatcgtaga gggtaggggg
    13441 gatagacatg taagagcgaa gtgcttcaga cgccagctgc tcaccgctgt tttcagtgtt
    13501 gttgtactga atgttattac tctgcgtctg gttaaccagc gccgttaaga cgtcagagaa
    13561 cactgaaatc agcgccgcac ctcgcagacg ctcccatata tgggtatcca cctgacccgg
    13621 aatccccgca ctgccgagtg agttcgttcc ggcactgtca atattaacga ttgtcccgtc
    13681 ctggtcattg cggatacgct cccagaggac aaacacgcgc gcctggccgt ctttgatacc
    13741 accggtaatc tgtccgtcaa cccatgagcc tttatcaatc agccttacga gtccgtcagc
    13801 tgagtacacg tcctgtgaaa cccggcagga aacctgcccc ggtacagtgg tatccagctc
    13861 agtgccggta ccacagggga tcattttgcc tttcggaaca gtcaggctgg gattagccaa
    13921 gacaccagcg cggcttgcct tcagccttgc aggagtcagg tttttagcaa gtgccgaact
    13981 accttcgctt gtttcgttgt cctggggctg cactccggga ctattgcttg tggccgcctg
    14041 attagtctgg gccagctcgc cacccagacg acgctgcata gccagttctt caggcgaagg
    14101 ttctttgcgc ttattagagg tacgcgcgcc ggtattgctg ctacccgcat ctgcatctgc
    14161 ctgtgcggca gcctgtacag cacgggcatc agtggcgcta ttctgcgcgg ttacaggctt
    14221 attaacatcg ggatcgctgt taaagctgta gtttggcagt gtattggcct gttgcgcttt
    14281 accgccgtct ttatcagctt cagctttagc cggggcgcga attttaccca tgaccgtaat
    14341 cccgatgaat accaaagcaa gcagcgccat cagtatgaca aaggctttca taccgggggc
    14401 cgaacggcgg ttactgcctt taaatccgcc acgctcgctt tcaaattcat cgtctccggt
    14461 gtttccatcg agttcctgat ctacatcgac acttttacgg gccatcagtt atcctcccca
    14521 atttgaaccc tgcgcacatc cggggaagcc gtaccggttg ctaccgcacc ggcgcccggc
    14581 gcgaaattat tattacgaac gccaacgact ttatcgccca gacgaatacg ccactcttta
    14641 gcgacggttt ccacctcgat gatgttgcgg ttctcaccca caacatgaga gttaggcagc
    14701 gtttctttgc cactggccga gatcatatag acctgcggta actccgcatt ggccggaaac
    14761 tcaaaccggg taaagcggta gttatcccag acgtgaaccg gctggatgct gcgcatttca
    14821 ggctgttcgc tcattacgta ctgatagttc ttcgcacccg caaaagccgt ctgcttcagc
    14881 ttctgcgtaa tgcgtttttt atcagccgcg cttttggctt tttcctgctg ctcaaacgga
    14941 tattcatagg tcagctgaag aacggcctgg cgcacagccc acggcgtttc aataaaggat
    15001 tttgataccg taccgtctgc atttttcttc gtttcttcac cgatgaaatg gaggacgatg
    15061 ttataggtgc gcttatcggt gacgatcacc aggttggtat cactcatggc ctgtttcggc
    15121 ttcacaaaaa aatggttcat tttgtgcgca aacgtccagc tttcagaatc gccaaaagca
    15181 tgagtgatat aggtttcgtc aggcgcgaca acaatgtggg tagccacacc ggcgatagcg
    15241 tcaattttga ccacgttaac agggttataa acaacgcttt taatgcggta gtcataagga
    15301 gaattgcggc caacctcaag cgccataacg ttagtggccg cgcctcccag gactgacaaa
    15361 acgactgctg aaagaagtag ttttttcatg gggcagccct cagttaactt ccgggttgac
    15421 gcgataactc gtcacgcgga aacccagcgg gttgacataa cgctgctcag cattcatcgc
    15481 cagcgattta tattcatacc ccataatggc aatccagcgc tgcggctgat catcaacggg
    15541 attgctgcgc acgcggcgaa ccgtagtaaa gcgtatcgtt gctacgccat gtggtttatc
    15601 gaggatcaca gagttaatct tcacgcgggt cgtttcactg tcgcccagaa ccttatcaag
    15661 accgttgcgg cccttgaact tgctctggta agactctgcc acgttcggcg tggacattaa
    15721 gccaacggcc gtataatcga cctgaactga atagaagtca tagctctcac ggtgaatgac
    15781 atattgtgtc agccagaact tatcaatctc gtcaccataa gaggtctggt cgcgggtcag
    15841 cttgacctgc tgtacttcgt gagtggcctc gttgagcgtt agcagatgtg cggggattgg
    15901 ctggctgtac ttatgcacca cgtaaccaac taaagagagt gcaaaaacag ttaccaccgc
    15961 tgaaccggtg gcaaccatcc aggcggtacg ccgggacttc agcacttcat ccatcagatc
    16021 aacttcaagc cctttacggc tttcgttgaa ctctttaatg gcttcacgtg taagccctgt
    16081 ttttttatta gctctcattt gcaccacctt gcgtatcaac cgggattgtt ttgtttactg
    16141 gaacggtgtt gctccagtcc ggctccggtg gcggtttatg cccgctggaa caggcgctaa
    16201 tcagaagaac tcccatgagt aataagctgc gcattacggc atccattatc ggttgttgaa
    16261 cgtactaatt ataataagtc gtcgaaattg caatttcaac gacttttgtt ttaattttat
    16321 gcagccttct tcccgcgact gccccttgcc ttaccactta aattagaacc actgtttcct
    16381 ccgctgttgc tgccacttcc tccacctgcc gattgctggc cgccgccact gttaccgcct
    16441 ctgaacgcat taccgccaaa catgccgtgg ctgcccatat tgccaagcgc ctgcatggaa
    16501 gaacccgtag agcgagcggc gtcagcaact ccggcgctga taccgctacc ccagctggcg
    16561 gcaatttgcg gaatctggaa cagaacgaaa acggaaatga ccgtcagtaa taaggcggcg
    16621 atagaaccag tgattgatga gtaagcggca tcagagttca tcgaggacag gaggttgtcg
    16681 aacatctgca tgatgaaacc aaacacgagc gcaagaatga cgacgacaag gccatagtta
    16741 atgaccgacg ccagccagcg agcaaagatg ttttttgtcg ctccccacag caggcagaag
    16801 attgcaatcg ggccaaaaca aagcgtaacg gccagaagga ttttagccat gatcacaaag
    16861 cccgcaccga ggccgcccag caccacggta gcaatcatca taatgccgcc aatggcatac
    16921 gcggccaggc cgctcgatga aaacacgtct gcggcttccc atgcggtgtt gacgatcttg
    16981 ataccttttt caataccgct atcaataatc gccggtacgc cacttgcacc gactttatta
    17041 ggggcagaca gtatcccggc aaaatcatcc ggcaggtgaa gcgccacgtt gaccagttcc
    17101 tgttgatacc agccgcccgc cgttgcaaag ctcaggataa gggctatgga aagatactct
    17161 ttaatcagcg aactcaggct gtcgcccgcc cccggattaa acgctgagta catcccctgc
    17221 accatcagct tgatggtcag acaggtggca atcagaggcg tcacatcaga gataatggtg
    17281 gcaacattgg cgctcaccat tgacgtaatc gccccgtcta cttttgcgaa aatgtctgcg
    17341 actagggtga atgccatatt gcctccttac tcctaaattt tcggtgaatt gatttcgccg
    17401 tcttttttgc cgaacacaaa cagctgacga tcggcttcgc gcgcgttttt gcaatcaggt
    17461 ttctgaagtt catccgcgtc tttcttgcat tcctgaattg ttgccttgcg ctctttctca
    17521 tgttttttgt accactccac gtcatgcgag gcatcgcagg ccaccaggag gaaagggata
    17581 acaagcagta gttttttcat aattacctca gttaattgaa ggtgacgcgg taacgtcccc
    17641 gccggttcca aaaacaaaat tgtgggtggc acgttctttc tgcgcacgta atagcttgtc
    17701 ctgtgactgc tgcaacatgt tcatcagatt cagcttcgcc tgctcaccct gaatagcacc
    17761 ctgtgacgtc tggatacggg cctgtaagtc agcaatcgat ttcaggtctg gcgtcgtttt
    17821 aatctgctcc gtcagctcct gcatatcggt cagttcctgc atctggttgt tgtaggcttt
    17881 ttctgccata acgcggtcat aagcgccttt ttcagccagc tttttgttca tgtaggtaat
    17941 tgcttcgctg ggcgtcatgt cgtcaacttc cgcattaaac tggcccatca tgctgttaac
    18001 tgaaggcgtg acggaagaac tggagttcat ggcgtcgctg tagatctcct tccagttgtc
    18061 cggcaaatta tttgccagcg tgctggtaga cgtccccagc agatcgccca ggtcggttgt
    18121 ctttgccatc gactcataca tatttttctg cgtttgcagc tggcttttaa gctgttccag
    18181 ctgctgcgcc atttgctgaa gctgctcgac ctgtttagcc agctcagtag ggttggtcac
    18241 gatgatgcct gcggaagcgc tttgcgcgcc ccccagaatc aggccggtgg tcagcagtac
    18301 tgccgtcagt gtttttttca tggtgttttg cctcattgtt aagccgtcag gcgccagtat
    18361 tctttgagcc atacttcagg gtcattaccg agccgttcaa ccagctcatg cgcaatttcg
    18421 gcgttttgtg gttcaccgga caacacgcta agaacgttgt ccattgtctt aatatctgca
    18481 tcaatatcgt cgctgttgcg tgggtagaga ttgaaagaag caatcgcaga ctgttgccct
    18541 tgtttaacta ggaactgtct ggagtgttcg gtaatcgaca tcagcgcgtc gtattcagca
    18601 tcagtaagga aggcataatc ctctcggata gcttccggat cgcgcaggca gattttcgtg
    18661 acggtctgcg acatgatcgt gcggccaata cggctggaca gcgcatcgtt cggctcctgc
    18721 gtggcaaaca catagatagc gtctttctta cggtcagttt tgataccacg cttaacttca
    18781 cgctcgataa ccggatcgtc aaggtaggcg tggaactcgt caaagcactg aatgacgcgg
    18841 cgtttgccgt cgatggagtc acgtacccgg tacagaaggt acatcatgag cggagtacgg
    18901 gccgggctgg atacttcctc tttggctgcg ataaactcgg acaaatcgaa gccaaaaata
    18961 tcattcgtgc tgagatccag gctgtcttta tcattgtcaa aaagccagcc atactgacct
    19021 tcgcgcgtcc attcgcgcag cagccctttc agtgatacgc cattttccac aacttcattc
    19081 acgtacccgt ccaggatagt aacggtgcgc gcctcgcgtg gaataagtga accttccccc
    19141 ataaccgcat caacgccttc agccagttcg gtagccatcg ttgcgctgat aggcccgtta
    19201 ttggtggttt ccacacaaat gcggaacagg tttttaatga gggcaatatt gcgtttggtc
    19261 ggctcaatct gaagcggggc aaacccggac ggcataccct gttgcagaac tttatagtag
    19321 ccaccaacgc ttcgaatgaa cggctccata ccgcggtcac ggtcataaac aaaaagccgt
    19381 gggttgtact tcattgactg cgccagcagg aagttaagca gtgtggtttt accttccccc
    19441 gacatacccg ttattaacgc gtggcccagc gggcgtttac cgtaagaaag ttcttcaagc
    19501 ggggtcacat gaaaattaaa atagagtggc gtaccgctga tcgtgcggaa catggtcagc
    19561 gctggccccc acgggttatt gtcaggcttg ccacgcataa aattgtggaa cgagctgaag
    19621 tgcaggaagt tccatgagtt taccggaacc gggcgcggcg cccatttctg gttgccaggc
    19681 agtttcgcat aatatgcagc ctcagaggcc aggctgatag taccgccaac cacgccacag
    19741 cctgtcagca taaccttcac acgacgcgct ttgcgctgta ccgcgttttg gtcattatcc
    19801 cagacatgca cagttccatg atggtagccc atcacgaact ctctggacgt cagcatatca
    19861 agcgcggtac caagctgtgc cagctggctt tgcgcacggt cgcgcgtttc ctgcaaagat
    19921 ttttcctgat gcgtcagaaa cgttttagct gaagattcag agaggcaaga aaaactctgc
    19981 gtcagaaggt attcaaaatc ggcttcttta agcatattga gctggcctgg ctctgtatct
    20041 tcttcgtagt cacgaaattc aatgccggtg gtgtaaaagt tgtgatctac cgttctgatc
    20101 tggacaacat caccccacag ggagcttaca gggcggttgt ccatgatgta ctcacggata
    20161 cgctcacggc aaacaggcac gatggcccat tccatatttg cgaggaaata aaggaactcc
    20221 agcgcttttg aataagcgtg agcctgcgaa ggctcaggct cgttacgttc gataacaaca
    20281 gcttcgtcaa aaacgtctga ttcatcgacc tcagccagtt cttcacgctc ttttttatca
    20341 ggcgccggaa tttcaacacc gcgtttgtca cgataataga tacccagctg ctgaatacca
    20401 tacggcttca ttgcttccag gatttgttca gaaacatctt ccagaccttc aagcgcctca
    20461 ttctgcattt gctgaatttg gtcacgagtc ggcttttcaa atttcgccag aaacttctgt
    20521 gtttgatccc ctacctgttt gtagataacg gtcagataaa ggtcattaat aagctgtttg
    20581 gaatcgccgt gcagcttacg gttatattga tcaacgtaag cagggaaaaa ctggtcatac
    20641 tcaccatccg ggtactcttt agcctcatgg tgatattcat gcgtccacag ctctacctgg
    20701 tctgttccga agctcttaac cagcgtatta aggtctttat gccaagtgac cagttcccga
    20761 tctgatgcgc agtcatgtgt gcggccatcc agcttgaaaa aagccatcag atcgccgttt
    20821 tccatcgaaa tcacgtaatc attgaggtga taagaatagg gcaaatactt tttatttacc
    20881 gatggctcct tacggaaggc atcaattttt tttggcttcg tagcggtggc agctctcatt
    20941 attttaaacc cttacgtttg tagtcagcag tggaataaga cgatcccccc cactgcttaa
    21001 acggagaatc aaaccaatta ctgaatttgg ttttcaacca caggcccata attcgaaaca
    21061 tgcggtcgtc atattttgtt aatgcagctg aaggaatcca caaaaagacg aacaccagga
    21121 tcgcccacat atgaataatc ataaagagcg aagcagagat catgaatatc aacatagcta
    21181 cattacgtgg tacacccagc gcgcgaggta agcgagtcgc acctttgaaa agcggtcttt
    21241 tcccgtcaac gaacatcttt gtagtcctca ctttggggga caaaagtccc cccttttcgc
    21301 gttggtcagc ttcctacacc cgtcagggaa accagatatg atgcagaacc aataccaatc
    21361 agtgcgatta cgatacgagg aataaagctg gctgggatta cgtgaagcat ccacataaag
    21421 caactaacca tgatcgcaat agcacaacca agtggaatcc atgtgttcag ccacgtctgg
    21481 attgatgtag cggttgattc accagtatcg gtgccagcgg ccagcgcgat ttgcggcagg
    21541 gcaattgaca aaacgcccat aactaccgca gggccatact tcttaaacaa cgtggtcata
    21601 ctttctcctt actcactatc ttctgttgat ttcagattta accggcattc ttcaacgcca
    21661 cacttatctt tcaaaaactc tgccagtagc cttaaatcag cccaggttcg tagctcatgc
    21721 tctttgttaa cccgaatgga acatgcgatc tggcccagct gttcatcgtc tatctgaaaa
    21781 acgggatacc acttctttaa tgaaacccgt tctatcgtta cctccttcac ttttcctgct
    21841 tcaaatagct ccaggatctg tgattgcaat acaaggtaca aacgttccat ccataacctc
    21901 actccccctt cgctgtttcc tgtttggtta aaaaggcatc cgtattattt cggctgaagg
    21961 catcgccatc acccgaacca aaaacatctt gttcaccgtc atactgcggc gccgtacttt
    22021 ttgcctgctg aggctcagtc gcggtgctgt cctcactggt ctggccgtca ggtagcagcg
    22081 tagggatttt caaatcagtt gattgacgcg ccacgttgat aactttcgtg acgtacccgt
    22141 tagaaatccc gtttgtgagt gagccggtgt tgtagcagga aagcgcgtgt ctcagcgcaa
    22201 cctgcccggc tgggtaggat ttcagggcgc tatcataaca ggctttaagg atggtctggc
    22261 tcgcccgcag gttgatgcag ggcttgaaaa tatcgtcaac cgaaagaccc aggcccacta
    22321 aattatttga gttaatttgt gcaaggccca tatcaaaact tttattatcc ttcagcagaa
    22381 ctttcgcaac gctgacggcc tcagcttcag tacgcggttg ctgttttaac tgggtactac
    22441 cgttaatatt gatcctgtac ggcccatttg aggactcatg gccgacgatg tacgccattg
    22501 ttaagggtga aacatcaggc gcacatctct gcgcaagcct ggcaatttca tcggaggcag
    22561 gcgcagcact ggcacggcca gcacaagcaa ggcaggccag agcgagaacc aggagttttg
    22621 gatgtttact catttacgtt tcaccgcgta attgtaattt cgacgacttt tgtttatgat
    22681 aagggctaat gagatcgtgt caagaagaaa cgaaaagaaa accgctgaag gaaggaaggt
    22741 gatgctggtt cccctgaaat cagaaaaacg acccaaaggc gaacccgtgt atcgtgaccc
    22801 ggataaccct tttaatacgt ggactggtat agggaagcgc ccggcctggc taactgcaaa
    22861 attggacgct ggcattagcc tggaagccat gaaaatgcag ggcgtagcca accccagaga
    22921 acatagacca gcaaaatacc gcgaccccag gaacgcagaa aatacctggt ccgggactgg
    22981 ccgccgacca acatggctca aagagctgct tgatagtggt ttatcacttg atgatctgaa
    23041 gatataaccg gagggtataa aaatgggcga aattattgat tttgcggaaa ggcaaaaagg
    23101 cagaaggaag aaaaaggcat cttccattcc gcccatttta agaaaatttc gtgtccatgc
    23161 gatcaggtta ctcgccagca tcatcaaatc cggctcttat tcagttgctt atatcgttaa
    23221 gaaaattaca ggaaagttaa tcaagttttt cacaatttta acgattttcg tttttgttgt
    23281 cgaatatatc gcaggcgata taggttacaa atctatttat aacgcagcgt tattattaat
    23341 gttacttacc gttatcaaca ttctggcggg tgtatatctg aacaaactgt taaggacaaa
    23401 acaatgaaga aactcttaat ccctctgata gcagctggta gtctgcttta tcttcctgcc
    23461 agccatgctg aagatccctg caaagttatt atgtgcatgg cgggcaagct caccggcgat
    23521 agcggcggaa gcgaatgtaa cagtgctgaa gctgctttct tcaatatcgt taaaaagaac
    23581 aagcacggct ttttacccaa ccacacgaag gatgccagga aggcttttct taatgaatgc
    23641 ccggataatg gcgaaggtgg aagtaaccag tcgatgataa gccagatcat aagtaaatac
    23701 gggaaagttc gcttataggc gaactaggaa taatctcaat ttaaggagcc aacgtgaaaa
    23761 aaattatatt aagtgcatta gcctgtacag ctctcttaac tggttgcgtc agccaggata
    23821 aaggtaatgc gatgcagagc cagctgaata accagcaacg ccagattaac gaattatccg
    23881 ttcgtttgca gtctgcggag tcccggctat caaagcagga agaaaagctg cgcaacgaac
    23941 tgctgcaatc cagcggctat tgctatctga atggcgcccg ctactcgacc ggcaccgtac
    24001 tttacgggcg gatttgccag aatcagtcag gcagcgcttc gtggcaggtt tacagccgtc
    24061 gctaaacacc agggcggttt aaccgccctt ttctttaccc acagaaagcc cactatgacc
    24121 atgttcccct tccccactac cgaaaacctt attctatggg cttgcagcgc catcgcactg
    24181 cttgccgttg tattcttccg gcgttcagta cggcaccggc gacacaaaag gaagcagcaa
    24241 agtgcgcggc gggtgctgga gcgcataaag acgttgccgg gcttcccaca aaaaattaac
    24301 tacctgcgga aaattgatcc ctttgtgttt gaagaactgt tgctggaagg atttgaagcg
    24361 catggcttca aaaccatcag aaacaaacgc tataccggcg atggaggcat tgacggccag
    24421 gtaataatag gaaaatatcg ctatcttatt caggctaaac gctatcgcgg ccatatcgcc
    24481 ttacagcacg tccaggagtt cgataacttg cttaaacgtc ataactgtcg tggcttgttt
    24541 tgccataccg ggaaaaccgg cgcaggttca aaatctgtca gtattgccag tgatcgaatg
    24601 gagattatca gcggccagcg cctgatagat ttgctcacgc ccggcagctc cttcactatc
    24661 gcaaccgccc cgcagacgat gatgaagcgt accgcagcaa cgcgagtaac gaacaccatt
    24721 gttaaagatg ccggtaatga aaatcgatac catgagagtt aattaaatga agtcagtaac
    24781 tatagaagca aaaacatttg ctgaaatgtt ggggataaca gaaggcgagt taatatttgc
    24841 cattaaaaca actggcaaat tcaaaaacaa aatcattcca caacctcatg agccacataa
    24901 atcgaaaagt cgattcttat actcggacgt agtgaaattt atcgaatcaa caaaagaaaa
    24961 agaaaacttg cataagaagt atttgatgcg ctttcgccgt tgcagctcac tggatactct
    25021 tgaaaaggta tttgagagct tgcgcgagaa gttatcaggt aaagaactgg atgctatgat
    25081 gagcgcctct gaccatagga gagcagaaat cactcacaat acattatggg ataaagtacc
    25141 cgcatctgca tggcgaaatg taaaatgaat aaagcccgat tccgggcttt atttctattc
    25201 cccacggcct ttcataccgt tagttatagt ctctattttc tttaattcat catatctctt
    25261 gtcttgttca taaagaaaat gactgatttt tactctatca tcccggacgg taagtaaatc
    25321 tttgctgttg aatagcccca taaaaaactc tctaaaccca tcatcatcag cgctacgttc
    25381 gaagtaatca aatagcaacg aggatgaaat agccgactta aatctccaaa atatgttggt
    25441 taacacaaaa acaataacaa acgctattga acacagtatc aactggttaa atttacttcc
    25501 tatcataaaa agaacaacga acccaacgat atttgaaagt tgaattttta agcgcagcct
    25561 tgaattataa acgtcatgat tatttatctt atcaagaatc tgttttccca aagataactc
    25621 gctaatagcc ataaattcac ctatccgatt aatactttta gtttagccct aacctcagct
    25681 aaaacagtag gaggtacttt tcctttcctg accgctccac gttcacgcca atcaaggttt
    25741 ttcacctggt cagccagcac agcgctcccc tcaccgttcc tgacctcaaa cggatagccc
    25801 tttatctttg ttgtcatagg gcagcacaac attaacccta ttttaccgtt atagatggcc
    25861 gggcttagca ctaatgctgg acggtggccc gcttgttcat gaccggcttg cggatcaaag
    25921 tttatccata caatatcacc ggcatcagga atataatcat gcttcattat ttagcctctt
    25981 gctaatataa acaacccata caaacgcaat gataagcacc ccactaaaaa taaacataat
    26041 tgcaaacgga gttgtatcaa gtaaagaaac cgcctcaaaa ccaccgatat ggatagagtt
    26101 atctctaaat atcttgctaa atcctaacca gatacaataa gttccaatac caaacacaac
    26161 cagggcacaa ataaactgca cgcagctaaa tattttcttt aatactttca gcataccccc
    26221 cctaaagaac ctttttaaac tttttcttcc attcatcgta actcatgtta cttttgtaat
    26281 gctccctcca cttctcccaa tgcttccggc ttatatcttc cagctccata tcaacttctg
    26341 cttcgcttaa aagcctggta aaacgtgccg aacttatacc agcatatttt ctgtgaaaat
    26401 cccgcccttc tttatggatt attacctgag tcattaaaga ccaatacagt ttattaagaa
    26461 gatatgcagc aacatacaac tgaacgagaa acataaccaa aagataacct acagacataa
    26521 ggtagccacc taagctgtaa gttccgtcat taaggtaaag gctggaatca ttataagtga
    26581 ccggcaattt tatcttaggt tgcatccagt taacccattc agagaaataa tatgaaactg
    26641 gattataagc taaaccaaaa acccctatag cggcatagta ggcgatccca attcctatga
    26701 cagcaaaaag gctcttacaa ccaaagctga accaccggat aaaggttctg ccatcttttt
    26761 tcattacaac aactccttcc cgactggagg cccaaatgaa acttcctcat gaatattttc
    26821 ggctgtaaca ccggccatca aagcatccag tgaatactcc ttcgttttaa ctggcacgat
    26881 agttattttc ccatcctcaa ctgacagctc cactacatca tcaacattca atgaagcagc
    26941 acggacaata gcagaaggaa ggcgaactga aggactatta ccccattttt taacagttac
    27001 ttgagtaccc atataaacct ctaattagtg aaataagtta accagtttaa taacaatcat
    27061 aatgaccatt actacagcaa acactccgac cagcaattta ataatttttg ctgaaagggt
    27121 attcgtaaaa gcggccccta tccctgacgc acaaaaccct atacaggccg cagctacagg
    27181 cgcccaggct ggtaatgggt ttttatctgt tatcatttcc agcattaaag gagctgtcgc
    27241 gagtataagc cccgcaataa acggaaaaag ccaagcgctg tttcgttgaa catacctttc
    27301 taacatcaca ccctcctaac gtatcattaa tgttgatacg gcgagtgtag aaccatcgtt
    27361 ttaacgtgtc aacaatgttg acacaattaa tgtctcaaaa acgatggttt ttgtgacagc
    27421 tatcaaaaga gctgagaaac ctgctttacc cccttccaaa cagtaacaaa actcgttaca
    27481 gtatcaatgt aacaataacc atgtaacaaa atcaggagcg caaatgtcga gtggcaactt
    27541 ttttagtccc gcaggtctga gtgcagcggc aacaattctg ctcacgctac cagggcaagt
    27601 acaagccagc gccgagaact atcaatacca aatgaaatac tcagctgatg ctcagtctat
    27661 tcgcccaact acggtattcg atgatggtaa ggctacatgg tttgtcattc cctctgaccc
    27721 aaaatcgccg cctgcgatac tgatcgtgac accggatgga aaagagaaac ttccagtccg
    27781 ttatgtaacg gccccgaatg cagataacac agcaataacc atcattgctt atgatgttgc
    27841 agaagaatgg cgtatacgca aaggagctat ggttgtagca gtcagaaacg agaatttcaa
    27901 aaacggcgtg acagtcacgg atcatgagaa aaaaatcagt aaagaagaac aaaaaattca
    27961 cgatgatatt gcggaatacc tgaccagatt gaacaccgtt tcaagccagg tagttattaa
    28021 gatgcaaaac attgatgttc atcctgaaaa caatagtgct gatttttcat atgccagatt
    28081 cattaaaacc acaaaaaata atgctgcata tgttaactat gaaaagatac aaggcaacct
    28141 aacataccgt tatgttgagc agcgtaaaga aaaaaacggc ccgcagcaaa agcctgtatt
    28201 tcaggtgcaa tcaattcaat ttaagactgt ggaaaataaa taatcatgat tattggttac
    28261 gcccgtaaat caacgcatct tcaggatgtg gcgcaccagg tagacgaact aaaaaaagct
    28321 ggttgtgaac aaatttatca ggaacaaacg tcacgcggag gcccaaaacg tgaaagcaaa
    28381 ggcgccccgg agctggagaa ctgcctgaag gctctacgag aaggcgatac actgattgtc
    28441 tgggcgctgg acaggctagg aggttcctta gcgcaggtca taaccttact ggacgatctg
    28501 aaaaagcgtg gtatcacctt tattgctatt aaagacagaa ttgatacgag cgcgcccgta
    28561 attggcgaag tctatacaca tctgatggca atattttcag catttgagcg taaccgaaat
    28621 atcgagcgaa cacgttcagg gttggcagct gctcgcgcaa ggggccgcgt tggaggaagg
    28681 aaacctgcat tatctgaaga agatattaaa cagataaaga ttcttttggc cgatcctgaa
    28741 atgaccgtta gtttagttgc gaaacggttt aatgtttcgc gtatgaccat ttaccgctat
    28801 acgaatagtg acaatgcttt ggctgacgaa gccggtaagg agtaatcatg gcagaggata
    28861 aaccgcttac taagcagcag cagaaaacag tcgaagcatc ggcacaaata aaacaagacc
    28921 cacccaaagg taacgacctg gcctttaccc attcaatttt gtgtcaggtt gggctaccaa
    28981 gatctaaacc ggaaggccgg gagtttatgc gccgttcagg ggatgcctgg cttgtcgtac
    29041 aagccggttg gcttgatgaa ggcaatgggc ctgtagaaca gtgcttacca tacggcccta
    29101 tgccgcgcct tgctatggcc tgggtatcgt catttgcgct acgcaacaaa acgcgtgaaa
    29161 tcaagatagg cagcagtgct aatgagttcc tgaagctgct ggggatggaa ccgcagggcg
    29221 ccaggcataa aactctaaga acgcaaatgc acgctttggc cgcttgcagg cttcagctcg
    29281 gttttcgtgg ccgaacgtat aacggccagc cagtagagca attcgacgca tggctaagaa
    29341 acgaagatag cgggcaacaa tcactttggc cgggcttact ggtgctttct gacggttact
    29401 ttaaaggact gctggaaagc gctgtgcctc tggataaccg cgcgcttagt gcgctaaaag
    29461 ggtctgccct ggcacttgat atttatgcct ggctggcgca ccgccttcac agaattgaag
    29521 gacgtcccgt tttactttat tgggctaacc tgcgcgatca atttgctcag gaatataaag
    29581 ggaaagaccc cgataaggat ttcaaaaaga aatttcttcc tgcgttaaaa gatgtattgg
    29641 cagtatatcc aaccgcaaaa gttcagcagg taaagggagg tattttactt tatccatcac
    29701 ctccccctat accatataaa ataccttaaa agacaaacgg gcctatacag gcccgtctta
    29761 ctatcaacac accggatatt aacgcggagc tatacctgcc tcagctaaag tccgcataat
    29821 agcatttatg ccatccatca tttcataagc ctcgttctca gacgtagaaa cgttaacgca
    29881 atcctgatgt gttgtacgtt tacagaattg agcaagcgcc cacgcttcag tattacttaa
    29941 ttcaagattc aggcttattt tatccaattc aacactcata tttatctccc aatctaagcc
    30001 gcattgttga tattaatgtt tattaaataa tcgaactggt gcgcgcaaaa gtcaatcaat
    30061 gtacgaatca tttttacctg tttttatgcc cgtcagggca tggaaggcga ccgcgccgga
    30121 ctccaccgga
//
LOCUS       DAPOXO010000064        29771 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPOXO010000064 DAPOXO010000000
VERSION     DAPOXO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29771
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.064"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..274
                     /locus_tag="ROH59_003311"
     CDS             <1..274
                     /locus_tag="ROH59_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HDX4805754.1"
                     /translation="LLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGD
                     IRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTLRESEV"
     gene            491..673
                     /gene="rzoD"
                     /locus_tag="ROH59_003312"
     CDS             491..673
                     /gene="rzoD"
                     /locus_tag="ROH59_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage lysis lipoprotein RzoD"
                     /protein_id="HDX4805755.1"
                     /translation="MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPPPPPAWIMQPPP
                     DWQTPLNGIISPSERG"
     gene            complement(764..1057)
                     /gene="iss"
                     /locus_tag="ROH59_003313"
     CDS             complement(764..1057)
                     /gene="iss"
                     /locus_tag="ROH59_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="increased serum survival lipoprotein Iss"
                     /protein_id="HDX4805756.1"
                     /translation="MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVS
                     GIGQKKTVDAAKICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ"
     gene            1538..1864
                     /locus_tag="ROH59_003314"
     CDS             1538..1864
                     /locus_tag="ROH59_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HDX4805757.1"
                     /translation="MKRRLLLLFLLSVLAVGCSQQKADEPRQLVTVYPRYPEYAAANY
                     IKGLVEVKFDIGADGTVTRIVFLRSEPHNLFRDEVVKAMAKWRFEKNRPCQGVKRQFI
                     FTPSRP"
     gene            2071..2253
                     /locus_tag="ROH59_003315"
     CDS             2071..2253
                     /locus_tag="ROH59_003315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805758.1"
                     /translation="MLAVFQLVKNTCSRLLQCLQHAAAMRLAFTNHLSFLYQSLRELI
                     MEYQVNADVIGFGYAA"
     gene            2817..3362
                     /locus_tag="ROH59_003316"
     CDS             2817..3362
                     /locus_tag="ROH59_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HDX4805759.1"
                     /translation="MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSA
                     DVIKWYAERDAEIENEKLRREVEELRQASETDLQPGTIEYERHRLTRAQADAQELKNA
                     RDSAEVVETAFCTFVLSRIAGEIASILDGIPLSVQRRFPELENRHVDFLKRDIIKAMN
                     KAAALDELIPGLLSEYIEQSG"
     gene            3337..5262
                     /locus_tag="ROH59_003317"
     CDS             3337..5262
                     /locus_tag="ROH59_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDX4805760.1"
                     /translation="MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFSNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHCMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLHVDEAINKTYT
                     RRNGAEMSVSRICWDIGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            5259..5465
                     /locus_tag="ROH59_003318"
     CDS             5259..5465
                     /locus_tag="ROH59_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family protein"
                     /protein_id="HDX4805761.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
     gene            5462..7063
                     /locus_tag="ROH59_003319"
     CDS             5462..7063
                     /locus_tag="ROH59_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDX4805762.1"
                     /translation="MKTPTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRAWNPPGES
                     VDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDHIVGSFFRLSHRPSWRYLGIGEE
                     DARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTS
                     SSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQK
                     WTWIPRELPGGRASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKA
                     MYAATIESELDTQSAMDFILGANSKEQRDRLTGWIGEIAAYYAAAPVRLGGAKVPHLM
                     PGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANES
                     WAYFMGRRKFVASRQASQMFLCWLEEAIARRVVTLPSKARFSFQEARSAWGNCDWIGS
                     GRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFAQQVRETMERRAAGLKPP
                     AWAAAAFESGLRQSTEEEKSDSRAA"
     gene            7044..8363
                     /locus_tag="ROH59_003320"
     CDS             7044..8363
                     /locus_tag="ROH59_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HDX4805763.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLT
                     DAVSGDSLTAGEAPAALALSVDDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYS
                     GMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPDDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSATASQADVTGVVPAT
                     EGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETAR
                     RILAVAPQSAQARSDTALDRLMQGAPAPLAAGNLASDAVNDLLNTPV"
     gene            8373..8705
                     /locus_tag="ROH59_003321"
     CDS             8373..8705
                     /locus_tag="ROH59_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HDX4805764.1"
                     /translation="MTSKETFTHYQPLGNSDPAHTATAPGGLSAKAPAMTPLMLDTSS
                     RKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAF
                     AGTAISIV"
     gene            8761..9786
                     /locus_tag="ROH59_003322"
     CDS             8761..9786
                     /locus_tag="ROH59_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDX4805765.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLV
                     DPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEEN
                     NITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKL
                     DTRRGSNSELETAVKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGN
                     TQARGLRTYGCIQDADAQLEGINASARYPKNWVTTGDPAREFTMIQSAPLMLLADPDE
                     FVSVQLA"
     gene            9828..10226
                     /locus_tag="ROH59_003323"
     CDS             9828..10226
                     /locus_tag="ROH59_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HDX4805766.1"
                     /translation="MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELEEELDDT
                     DETAGQDTPLSRENVLTGHENEVGSAQPDTVILDTSELVTVVALVTLHTDALHATRDE
                     PVAFVLPGTAFRVSAGVAAEMTERGLARMQ"
     gene            10238..10591
                     /locus_tag="ROH59_003324"
     CDS             10238..10591
                     /locus_tag="ROH59_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HDX4805767.1"
                     /translation="MADFDNLFDAAIVRADETIRGYMGTSATMTSGEQSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDTLTIGEENFWIDRISTDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            10603..11181
                     /locus_tag="ROH59_003325"
     CDS             10603..11181
                     /locus_tag="ROH59_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4805768.1"
                     /translation="MAIKGLEQAVENLSRISRTAVPGAAAMAINRVASSAISQSASQV
                     ARETKVRRKLVKERARLKRATVKNPQARIKVNRGDLPVIRLGNARVVLSRRRRRKKGQ
                     RSSLKGGDSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTT
                     AFKQNIERIRRERLPKELGYALQHQLRMVIKR"
     gene            11178..11573
                     /locus_tag="ROH59_003326"
     CDS             11178..11573
                     /locus_tag="ROH59_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4805769.1"
                     /translation="MKHTELRAAVLDALEKHDTGATLFDGRPAVFDEEDFPAVAVYLT
                     GAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDSWMESRIYPVMSDVPALSDLITSM
                     VASGYDYRRDDDAGLWSSADLTYVITYEM"
     gene            11581..12321
                     /locus_tag="ROH59_003327"
     CDS             11581..12321
                     /locus_tag="ROH59_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4805770.1"
                     /translation="MPVPNPVMPVKGAGTTLWVYKGNGDPYANPLSDVDWSRLAKVKD
                     LTPGELSAESYDDSYLDDEDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNE
                     GDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
                     TTGMTVTPASASVVKGQSTTLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVNG
                     VAAGKVNIPVVSGNGEFAAVAEITVTAS"
     gene            12337..12759
                     /locus_tag="ROH59_003328"
     CDS             12337..12759
                     /locus_tag="ROH59_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HDX4805771.1"
                     /translation="MFLKTESFEYNGVTVTLSELSALQRIEHLALMKRQAEPAGSDSN
                     RQVTVEDVIRTGAFLVAMSLWHNHPKKTQMPSMNEAVKQIEQEVLTTWPTEAISHAEN
                     VVYRLSGMYEFVVNNAPEQAEDAGPAEPVSAGKCSTVS"
     gene            12741..13175
                     /locus_tag="ROH59_003329"
     CDS             12741..13175
                     /locus_tag="ROH59_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HDX4805772.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPASPDVADMTEDDVMLMTVSEGIAGGVRYG"
     gene            13168..15729
                     /locus_tag="ROH59_003330"
     CDS             13168..15729
                     /locus_tag="ROH59_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDX4805773.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTESDAKKTAAVV
                     EQSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQA
                     GLTADRMLVLSRAGQAAGLTFNQTSESLSALVKAGVSGEAQIASISQSVARFSSASGV
                     EVDKVAEAFGKLTTDPTSGLTAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAA
                     TKGFDDQTRRLKENMGTLETWADRTARAFKSMWDAVLDIGRPDTAQEMLIKAEAAFKK
                     ADDIWNLRKDDYFVNDEARARYWDDREKARLALEAARKKAEQQSQQDKNAQQQSDTEA
                     SRLKYTEEAQKAYERLQTPLEKYAARQEELNKALKDGKILQADYNTLMAAAKKDYETT
                     LKKPKQSGVKVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDLWKAESQ
                     FAVLEEAAQRRQLSVQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFA
                     QQQRAKRAAIDAKSRGLTDRQAEREATEQRLKEQYGDNPLALNNVMSEQKKTWAAEDQ
                     LRGNWMAGLKSGWSEWEESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQNWRSFTR
                     SVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFATGGFTG
                     TGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMADSRSQAS
                     GTFEQNNHVVINNDGTNGQIGPAALKAVYDMARKGARDEIQTQMRDGGLFSGGGR"
     gene            15726..16055
                     /locus_tag="ROH59_003331"
     CDS             15726..16055
                     /locus_tag="ROH59_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4805774.1"
                     /translation="MKTFRWKVKPGMDVASVPSVRKVRFGDGYSQRAPAGLNANLKTY
                     SVTLSVPREEATVLESFLEEHGGWKSFLWTPPYEWQQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            16055..16753
                     /locus_tag="ROH59_003332"
     CDS             16055..16753
                     /locus_tag="ROH59_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDX4805775.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            16758..17501
                     /locus_tag="ROH59_003333"
     CDS             16758..17501
                     /locus_tag="ROH59_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4805776.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVVRTPKGERYFPCVNISGEPE
                     AYFRMSPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGEIHK
                     FRCVPHLTGRCFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRHGQNLYLDNLEAT
                     GLYQVPLSSAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWRASAFTGIYNDLAAASTFV"
     gene            17438..18040
                     /locus_tag="ROH59_003334"
     CDS             17438..18040
                     /locus_tag="ROH59_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDX4805777.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLSD
                     GWYQVRIAGRDTGETELSARLNEPLANGAVIHIVPRLAGAKSGGVFQAVLGAAVMAVA
                     IWMPGVGIMASNLLFSLGASMTLGGVAQMLAPKPRTPRTQTTDNGKQNTYFSSLDNMV
                     AQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            18101..21583
                     /locus_tag="ROH59_003335"
     CDS             18101..21583
                     /locus_tag="ROH59_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDX4805778.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQSPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLLNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTLKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKETIVDNGAHFDGEQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFMLRLTVAADDGSERLVSTARTTETTYRFRQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVEASARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITSGGNP
                     PTFSLTPDGRLSARNADISGNVNANSGTLNNVTINQNCRILGKLSANQIEGDIVKTVG
                     KAFPRNGSYASGTITVTVYDDQAFDRQIVVPPVLFRGGKHENFNSNNQQSYWYSTCKL
                     QVLKNGQEIFQQPATDVSRVFSSVIDMPAGHGHVTLTFNVSSYGANNWTPTTSISDLL
                     VVVMKKSTAGISIS"
     gene            21642..23663
                     /locus_tag="ROH59_003336"
     CDS             21642..23663
                     /locus_tag="ROH59_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HDX4805779.1"
                     /translation="MAVQISGVLKDGAGKPIQNCTIQLKAKRNSTTVVVNTVASENPD
                     EAGRYSMDVEYGQYSVALLVEGFPPSHAGTITVYEDSKPGTLNDFLGAATEDDVCPEA
                     LYRFEKMVEEAARNAEAASQSAAAAKKSETAAASSRNAAKTSETNAGNSAKAAASSKT
                     AAQNAATAAERSETNARASEEASADSEEASRRNAESAAENAGVATTKAREAAADATKA
                     GQKKDEALSAATRAEKAADRAEAAAEVTAEPCANIVPPLPDVWIPFNDSLDMITGFSP
                     SYKKIVIGDDEITMPGDKIVKFKRASTATYINKSGQLKLAEVDEPRFERDGLLIEGQR
                     TNYLRNSNKPDSWTVHSALNKTFGTDKQGFNYATVTPTESIVGTTGGYTVHGVVAADR
                     FPLASGECFTFSCRVKGAKARCRLRVSVIIGGTDTFSADSYLDLDTRIATVSGNTSLI
                     TAKAEQQGEWTYYEATYTANTDIDTVNCAFYMTNKISNETFYDDSTLTMTTPQIELGN
                     TASSFIVTTMPTTRASDVVTIPSQNNLSTRPFTVLCEVSRNWSTPPNVAPRIFDVGGH
                     SIDDNYLSLGFVATGKISANVGMVQPQIASDGERFIVGVRAKSDLSVNAICNGNYTTN
                     LNGKIFGVTATSYRFGGQTAAGTRHLFGHIRNFRVWFKELNDRQIKEAV"
     gene            23660..23938
                     /locus_tag="ROH59_003337"
     CDS             23660..23938
                     /locus_tag="ROH59_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805780.1"
                     /translation="MKDLTLKFPGNREFKSFLSSLDWEEDEDLQNKLLVDEIGFTYTE
                     TGVTEEGEPVCVRNDGYFVNIRILDDLFDVSVFSDYVVELETPLREWS"
     gene            23951..24244
                     /locus_tag="ROH59_003338"
     CDS             23951..24244
                     /locus_tag="ROH59_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805781.1"
                     /translation="MDISPLLHALCAVAAQILVGLFTGNWAYGAIAGCTFFIAREHTQ
                     AEYRWIEMFGHGKRMNMPWWGGFDPRAWDVASLMDFAVPVVACLLVWLLVNRG"
     gene            complement(24336..25193)
                     /gene="sitD"
                     /locus_tag="ROH59_003339"
     CDS             complement(24336..25193)
                     /gene="sitD"
                     /locus_tag="ROH59_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitD"
                     /protein_id="HDX4805782.1"
                     /translation="MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKGWALMG
                     DAMSHAVFPGIVLAWILGLPLATGAFVAGVFCAVATGYLKDNSRIKQDTVMGIVFSGM
                     FAAGLILYIAVKPDVHLDHILFGDMLGITIGDIIQTMIIAGLVTLVISVKWRDFLLFS
                     FDYQQAQVSGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRF
                     HIALLLATGISVIVSMTGVWLSFFIDSAPAPTIVVLFAVLFIMTFAVTSINARKKGNS
                     HTQDLLSPN"
     gene            complement(25190..26047)
                     /gene="sitC"
                     /locus_tag="ROH59_003340"
     CDS             complement(25190..26047)
                     /gene="sitC"
                     /locus_tag="ROH59_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitC"
                     /protein_id="HDX4805783.1"
                     /translation="MNVLLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGD
                     ALSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSMLFLNQRTRLKEDAIIGLIFSSFF
                     GLGLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFF
                     DENHARAIGLHPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFP
                     RLLMIAVTIGSVTSFLGAWVSYFLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRR
                     AHKALEDRS"
     gene            complement(26044..26871)
                     /gene="sitB"
                     /locus_tag="ROH59_003341"
     CDS             complement(26044..26871)
                     /gene="sitB"
                     /locus_tag="ROH59_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter ATP-binding
                     protein SitB"
                     /protein_id="HDX4805784.1"
                     /translation="MMQSAGIVVNDVTVTWRNGHTALRDASFTVPSGSIAALVGVNGS
                     GKSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLVAYVPQSEDVDWSFPVLVEDVVM
                     MGRYGHMGMLRIAKKRDRQIVTDALERVDMVNFRHRQIGELSGGQKKRVFLARAIAQQ
                     GDVILLDEPFTGVDVKTEAKIISLLRELRAEGKTMLVSTHNLGSVTTFCDYTVMVKGT
                     VLASGPTDTTFTAENLELAFSGVLRHVTLNGSEESIITDDERPFVAHRPSAVQREER"
     gene            complement(26871..27785)
                     /gene="sitA"
                     /locus_tag="ROH59_003342"
     CDS             complement(26871..27785)
                     /gene="sitA"
                     /locus_tag="ROH59_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter substrate-binding
                     protein SitA"
                     /protein_id="HDX4805785.1"
                     /translation="MHSIKKVTMLLGGLALTCSIAFQASATEKFKVITTFTIIADMAK
                     NVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMNLELWFQRFYQHLNG
                     VPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAQTYQ
                     RNADTYKAKITQTLAPLRKQITELPENQRWMVTSEGAFSYLARDLGLKELYLWPINAD
                     QQGTPQQVRKVVDIVKKNHIPAVFSESTISDKPARQVARETGAHYGGVLYVDSLSTEN
                     GPVPTYIDLLKVTTSTLVQGIKAGKREK"
     gene            28483..29241
                     /locus_tag="ROH59_003343"
     CDS             28483..29241
                     /locus_tag="ROH59_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805786.1"
                     /translation="MKTLSGKEFRKLFNRYETGFYLSEFEYLKDFDPLFPECVGKELK
                     LGYKRKVDVWCEEDAALYAEFIATKERLKRGRLILKINQVWSRVYPAYIYAIEERINV
                     RAKGRESFKYETVQEKQCKLSIMLDGLKDLECEIAMISSEFEIEKHSMHYFYMIFDIE
                     RYINDCSYFVFSAAKVVKGVIQCIGYIDKNNKASCDEFYSGSYECLDDDQETLNYLNE
                     SCAEGIDADKDLIRKNELLALSLKELYQLLVSKK"
BASE COUNT         7385 a         7125 c         8652 g         6609 t
ORIGIN      
        1 gcttctttca cgctggtggg atgcttaccg taaacagctt ggtttgaaag acttctcccc
       61 caaaagccag gacgcagtgg cattacagca gattaaagag cgtggtgctt taccgatgat
      121 tgatcgcggt gatatccgtc aggcaatcga ccgttgcagc aatatctggg cttcactgcc
      181 gggcgctggt tatggtcagt tcgagcataa ggctgacagc ctgattgcaa aattcaaaga
      241 agctggcgga acgctcagag agagtgaggt atgagcagaa taaccgcgat tatctccgct
      301 ctggttatct gcgtcatcgt ctgcctttca tgggcggtta atcattaccg cgataacgcg
      361 attacctaca aagcccagcg cgacaaaaat gccagagaac tgacgctggc gaacgcggca
      421 attactgaca tacagatgcg tcagcgtgat gttgctgcgc tcgatgcaaa atacacgaag
      481 gagttagctg atgcgaaagc tgaaaatgat gctctgcgtg atgatgttgc cgctggtcgt
      541 cgtcggttgc acatcaaagc agtctgtcag tcagtgcgtg aagccaccac cgcctccggc
      601 gtggataatg cagcctcccc ccgactggca gacaccgctg aacgggatta tttcaccctc
      661 agagagaggc tgatcactat gcaaaaacaa ctggaaggaa cccagaagta tattaatgag
      721 cagtgcagat agagctgccc atatcgatgg gcaactcatg caattattgt gagcaataca
      781 cacgcgcttc cagcggagta taaatgccta aagtaataaa accgagcaat ccatttacga
      841 atgtttgctg ggtttctgtt ttaacaacat tttctgcacc accacaaatt tttgctgcat
      901 cgacagtttt cttctgccca attcccgaaa cgaagaaatg atgggtgatg gtttcctttg
      961 gtgttactgc tgtaggtttg tttccaacag taaacgtctg ttgagcacat cctgtaataa
     1021 gcattgccag agcggcagaa aacaacattt ttttcatctt attatcctgc attgttaaaa
     1081 acggcagaat cctatgtgac aacaattaaa cgatagttaa atggattgat gaaaattaaa
     1141 actacacagg tgggctcaga ctattggagg aagttgggga cactcagaat cctgtggaat
     1201 gaaataaacc ggtctatccg tccattaccc ttttagctgc gctgtatcgt cgccgtattc
     1261 ccgcattaac catgaccgta gcccgacggg gaattccttc tgcgtgagtg tgcgggaata
     1321 attaaaaacg atgcacaccg ggtttttacc gcgttaatga ttcgcgggtt tatcccggtg
     1381 cgatggtgga agaaacagga agctgtatta cagaaagtgc tactactgta tcccgatgcg
     1441 atgtatgtaa tgtgagtcag ataatggcac aggatgtggt gatgtggcag tctggaacac
     1501 aggatatatt gtcagaataa gacccgtagg aataaaaatg aaaagacgcc ttttactact
     1561 ttttctgtta tctgtcctgg cagtgggatg ctcgcagcaa aaagctgatg agccccggca
     1621 attagtgacg gtgtatccac gatatccgga atatgctgca gcaaattata tcaaggggct
     1681 ggttgaggtt aagttcgata ttggtgctga tgggactgtg acacggatcg tttttctccg
     1741 ctcagagcct cataatttgt ttcgtgatga agtggtgaag gccatggcga aatggcgatt
     1801 tgaaaagaat cgcccctgtc agggagtgaa gagacaattt atctttacgc cgtcacgtcc
     1861 ttgatgcttc caggtagaga ggggctggaa gcaggagaaa aatgaaagag ccagcggtta
     1921 tatttttgtc atggctgacg aggaatgatg gaagaaggcg ttgtatgcca cacaacgcct
     1981 cactgttcat ttcttctttt tctctggtgg aacccgatga ataagagttg cactggtttc
     2041 cgatgagatg gcgatatact cgggcaaagt atgctggcag ttttccaact ggtcaaaaat
     2101 acctgctctc gtctgttgca atgcctgcag catgcggcgg caatgcgcct tgcttttact
     2161 aaccatcttt ccttcctcta tcagtcgctg cgtgaactca tcatggaata ccaggtaaat
     2221 gcggatgtta tcggttttgg ctacgcagca tagtacaaaa cggacaggtg catcccggga
     2281 cgggggaggc gtcacatgtc cctgtgatgg ttgttccggg taatgtactg tgtggggcat
     2341 aaaaatgtcc gataatttta ctttctaccg cagttagttg attcgttggt cctggtagca
     2401 cattgggcga ggatttaaat gccaggcaac tgaaggatga tgtcgcaagg gagatagcga
     2461 gaatatttct gattttcatt tgatgatgcc tctgtgtgaa atgacggtaa acgacgcact
     2521 tgtgccggca cataatagca agcaccataa tagatcagat tcgattcttg ctgtaagtga
     2581 taattattct cgttttcggg tcctttccgt cgatccaaca ggttacgggg cggcgacctc
     2641 gcgggttttc gctatttatg aaaattttcc ggtttaaggc gtttccgttc ttcttcgccg
     2701 taacttaatg tttttattta aaacactccc tgaaaagaaa ggaaacgaca ggtgctgaaa
     2761 acgggctttt tggcctctgt cgtttccttt ctctgttttt gtccgtggaa tgaacaatgg
     2821 aagtcaacaa aaagcagctg gctgacattt tcggcgcgag tatccgtact attcagaact
     2881 ggcaggagca gggaatgccc gttctgcgag gcggtgggaa gggtaatgag gtgctttatg
     2941 actctgccga cgtcataaaa tggtatgccg aaagggatgc tgaaattgag aacgaaaagc
     3001 tgcgccggga ggttgaagaa ctgcgacagg ccagcgagac agatctccag ccagggacta
     3061 ttgagtacga acgccatcga cttacgcgtg cgcaggccga cgcacaggag ctgaaaaatg
     3121 ccagagactc cgctgaagtg gtggaaaccg cattctgtac tttcgtgctg tcgcggatcg
     3181 caggtgaaat tgccagtatt ctcgacggga tccccctgtc ggtgcagcgg cgttttccgg
     3241 aactggaaaa ccgacatgtt gatttcctga aacgggatat catcaaagcc atgaacaaag
     3301 cagccgcgct ggatgaactg ataccggggt tgctgagtga atatatcgaa cagtcaggtt
     3361 aacaggctgc ggcattttgt ccgcgccggg cttcgctcac tgttcaggcc ggagccacag
     3421 accgccgttg aatgggcgga tgctaattac tatctcccga aagaatccgc ataccaggaa
     3481 gggcgctggg aaacactgcc ctttcagcgg gccatcatga atgcgatggg cagcgactac
     3541 atccgtgagg tgaatgtggt gaagtctgcc cgtgtcggtt attccaaaat gctgctgggt
     3601 gtttatgcct actttataga gcacaagcag cgcaacaccc ttatctggtt gccgacggat
     3661 ggtgatgccg agaactttat gaaaacccac gttgagccga ccatccgcga tattccgtcg
     3721 ctgctggcgc tggctccgtg gtatggcaaa aagcaccggg ataacacgct cactatgaag
     3781 cgtttttcca atggtcgtgg cttctggtgc ctgggcggta aagcggcaaa aaactaccgt
     3841 gaaaagtcgg tggatgtggc gggttatgat gaacttgctg cctttgatga ggatattgaa
     3901 caggaaggct ctccgacgtt ccttggcgac aaacgtattg aaggctcggt ctggccaaag
     3961 tccatccgtg gctccacgcc caaagtgaga ggcacctgtc agattgagcg tgcagccagt
     4021 gaatccccgc attgtatgcg ttttcatgtt gcctgcccgc actgcgggga ggagcagtac
     4081 cttaaatttg gcgataaaga gacgccgttt ggcctcaaat ggacgccgga tgatccctcc
     4141 agcgtgtttt atctctgcga acataatgcc tgcgtcatcc gccagcagga gctggacttc
     4201 actgatgccc gttatatctg cgaaaagacc gggatctgga cccgtgatgg cattctctgg
     4261 ttttcgtcat ccggtgaaga gattgagccg ccggacagcg tgacctttca catctggacg
     4321 gcgtacagcc cgttcaccac ctgggtgcag attgtcaaag actggatgaa aacgaaagga
     4381 gatacgggaa aacgtaaaac cttcgtgaac accacgctcg gtgagacatg ggaagcgaaa
     4441 atcggtgaac gtccggatgc tgaagtgatg gcagagcgga aagagcatta ttcagcgccc
     4501 gttcctgacc gtgtggctta cctgactgcc ggtatcgact cccagctgga tcgctacgaa
     4561 atgcgcgtat ggggatgggg gccgggtgag gaaagctggc tgattgaccg gcagattatt
     4621 atgggccgcc acgacgatga acagacgctg ctgcatgtgg atgaggccat caataaaacc
     4681 tatacccgcc ggaatggtgc agaaatgtcg gtatcccgta tctgctggga tattggcggg
     4741 attgacccga ccatcgtgta tgaacgctcg aaaaaacatg ggctgttccg ggtgatcccc
     4801 attaaagggg catccgtcta cggaaagccg gtggccagca tgccacgtaa gcgaaacaaa
     4861 aacggggttt accttacgga aatcggtacg gataccgcga aagagcagat ttataaccgc
     4921 ttcacactga cgccggaagg ggatgaaccg cttcccggtg ccgttcactt cccgaataac
     4981 ccggatattt ttgatctgac cgaagcgcag cagctgactg ctgaagagca ggtcgaaaaa
     5041 tgggtggatg gcaggaaaaa aatactgtgg gacagcaaaa agcgacgcaa tgaggcgctc
     5101 gactgcttcg tttatgcgct ggcggcgctg cgcatcagta tttcccgctg gcagctggat
     5161 ctcagtgcac tgctggcgag cctgcaggaa gaggatggtg cagcaaccaa caagaaaaca
     5221 ctggcagatt acgcccgtgc cttatccgga gaggatgaat gacgcgacag gaagaacttg
     5281 ccgctgcccg tgcggcactg catgacctga tgacaggtaa acgggtggca acggtacaga
     5341 aagacggacg gcgagtggag tttacggcca cttccgtgtc tgacctgaaa aaatacattg
     5401 cggagctgga ggtgcagacc ggcatgacac agcgacgcag gggacctgca ggattttatg
     5461 tatgaaaacg cccaccattc ccacccttct gggaccggac ggcatgacat cgctgcgtga
     5521 atatgccggt tatcacggcg gtggcagcgg atttggtggg cagttgcggg cgtggaaccc
     5581 accgggtgaa agtgtggatg cagccctgct gcccaacttt acccgtggca atgcccgcgc
     5641 agacgatctg gtacgcaata acggctatgc tgccaacgcc atccagctgc atcaggatca
     5701 tatcgtcggg tcttttttcc ggctcagtca tcgcccaagc tggcgctatc tgggcatcgg
     5761 ggaggaagac gcccgtgcct tttcccgcga ggttgaagcg gcatggaaag agtttgccga
     5821 ggatgactgc tgctgcattg acgttgagcg aaaacgcacg tttaccatga tgattcggga
     5881 aggtgtggcc atgcacgcct ttaacggtga actgttcgtt caggccacct gggataccag
     5941 ttcgtcgcgg cttttccgga cacagttccg gatggtcagc ccgaagcgca tcagcaaccc
     6001 gaacaatacc ggcgacagcc ggaactgccg tgccggtgtg cagattaatg acagcggtgc
     6061 ggcgctggga tattacgtca gtgaggacgg ctatcctggc tggatgccgc agaaatggac
     6121 atggataccc cgtgagttac cgggcggtcg tgcttcgttc attcacgtct ttgaacccgt
     6181 ggaggacggg cagacccgcg gtgcaaatgt gttttacagc gtgatggagc agatgaagat
     6241 gctcgacacg ctgcagaaca cgcagctgca gagcgccatt gtgaaggcga tgtatgccgc
     6301 caccatcgag agtgagctgg atacgcagtc agcgatggat tttattcttg gcgcgaacag
     6361 taaggagcag cgggacaggc tgaccggctg gattggtgaa attgccgcgt attacgccgc
     6421 agcaccggtc cggctgggag gcgcaaaagt gcctcacctg atgccgggtg actcactgaa
     6481 cctgcagacg gctcaggaca cggataacgg ctactccgtg tttgagcagt cactgttgcg
     6541 gtatatcgct gccgggctgg gtgtctcgta tgagcagctt tcccggaatt acgcccagat
     6601 gagctactcc acggcacggg ccagtgcgaa cgagtcgtgg gcgtacttta tggggcggcg
     6661 aaaattcgtc gcatcccgtc aggcgagcca gatgtttctg tgctggctgg aagaggccat
     6721 cgctcgccgc gtggtgacgt taccttcaaa agcgcgcttc agttttcagg aagcccgaag
     6781 tgcctggggg aactgcgact ggataggctc cggtcgtatg gccatcgatg gtctgaaaga
     6841 agtacaggaa gcggtgatgc tgatagaagc cggactgagt acctacgaga aagagtgcgc
     6901 aaaacgcggt gacgactatc aggaaatttt tgcccagcag gtccgtgaaa cgatggagcg
     6961 ccgtgcagcc ggtcttaaac cgcccgcctg ggcggctgcg gcatttgaat ccgggctgcg
     7021 acaatcaaca gaggaggaga agagtgacag cagagctgcg taatctcccg catattgcca
     7081 gtatggcctt taatgagccg ctgatgcttg aacccgccta tgcgcgggtt ttcttttgtg
     7141 cgcttgcagg ccagcttggg atcagccgcc tgacggatgc ggtatccggc gacagcctga
     7201 ctgccggaga ggcacccgcg gcgctggcgt tatccgttga tgatgacgga ccacgacagg
     7261 cccgcagtta tcaggtcatg aacggcatcg ccgtgctgcc ggtgtccggc acgctggtca
     7321 gtcggacgcg agcgctgcag ccgtattcgg ggatgaccgg ttacaacggc attatcgccc
     7381 gtctgcaaca ggctgccagc gacccgatgg tggacggcat tctgctcgat atggatacgc
     7441 caggcgggat ggtggcaggg gcatttgact gcgctgacat catcgcccgt gtgcgtgaca
     7501 taaagccggt atgggcgctg gccaacgaca tgaactgcag tgcaggtcag ttgcttgcca
     7561 gcgccgcctc ccgacgtctg gtcacgcaga ccgcccggac aggctccatc ggcgtcatga
     7621 tggctcacag taattacggt gctgcgctgg agaaacaggg cgtggaaatc acgctgattt
     7681 acagcggcag ccataaggtg gatggcaacc cctacagcca tctaccggat gatgtccggg
     7741 aaacactgca gtcccggatg gatgcaaccc gccggatgtt tgcacagaag gtgtcggcat
     7801 ataccggcct gtccgtgcag gctgtgctgg ataccgaggc tgcagtgtac agcggtcagg
     7861 aggccattga tgccggactg gctgatgaac ttgttaacag taccgatgcg atcaccgtca
     7921 tgcgtgatgc actggatgca cgtaaatccc gtctctcagg agggcgaatg accaaagaga
     7981 ctcaatcaac aactgtttca gccactgctt cgcaggctga cgttactggc gtggtgccag
     8041 cgacggaggg cgagaacgcc agcgctgcgc agccggacgt gaacgcgcag atcaccgcag
     8101 cggttgcggc agaaaacagt cgcattatgg ggatcctcaa ctgtgaggaa gctcacggac
     8161 gcgaagaaca ggcacgcgtg ctggccgaaa cccctggtat gaccgtggaa acggcccgcc
     8221 gcattctggc agttgcacca cagagtgcac aggcgcgcag tgacactgcg ctggatcgtc
     8281 tgatgcaggg ggcaccggca ccgctggctg caggtaacct ggcatctgat gccgttaacg
     8341 atttgctgaa cacaccagtg taagggatgt ttatgacgag caaagaaacc tttacccatt
     8401 accagccgct gggcaacagt gacccggctc ataccgcaac cgcgcccggc ggattgagtg
     8461 cgaaagcgcc tgcaatgacc ccgctgatgc tggacacctc cagccgtaag ctggttgcgt
     8521 gggatggcac caccgacggt gctgccgttg gcattcttgc ggttgctgct gaccagacca
     8581 gcaccacgct gacgttctac aagtccggca cgttccgtta tgaggatgtg ctctggccgg
     8641 aggctgccag cgacgagacg aaaaaacgga ccgcgtttgc cggaacggca atcagcatcg
     8701 tttaacttta cccttcatca ctaaaggccg cctgtgcggc tttttttacg ggattttttt
     8761 atgtcgatgt acacaaccgc ccagctgctg gcggcaaatg agcagaaatt taagtttgat
     8821 ccgctgtttc tgcgtctctt tttccgtgag agctatccct tcaccacgga gaaagtctat
     8881 ctctcacaaa ttccgggact ggtaaacatg gcgctgtacg tttcgccgat tgtttccggt
     8941 gaggttatcc gttcccgtgg cggctccacc tctgaattta cgccgggata tgtcaagccg
     9001 aagcatgaag tgaatccgca gatgaccctg cgtcgcctgc cggatgaaga tccgcagaat
     9061 ctggtggacc cggcttaccg ccgccgtcgc atcatcatgc agaacatgcg tgacgaagag
     9121 ctggccattg ctcaggtcga agagatgcag gcagtttctg ccgtgcttaa gggcaaatac
     9181 accatgaccg gtgaagcctt cgatccggtt gaggtggata tgggccgcag tgaggagaat
     9241 aacatcacgc agtccggcgg cacggagtgg agcaagcgtg acaagtccac gtatgacccg
     9301 accgacgata tcgaagccta cgcgctgaac gccagcggtg tggtgaatat catcgtgttc
     9361 gatccgaaag gctgggcgct gttccgttcc ttcaaagccg tcaaggagaa gctggatacc
     9421 cgtcgtggtt ctaattccga gctggagaca gcggtgaaag acctgggtaa agcggtgtcc
     9481 tataagggga tgtatggcga tgtggccatc gtcgtgtatt ccggacagta cgtggaaaac
     9541 ggcgtcaaaa agaacttcct gccggacaac acgatggtgc tggggaacac tcaggcacgc
     9601 ggtctgcgca cctatggctg cattcaggat gcggacgcac agctcgaagg cattaacgcc
     9661 tctgcccgtt acccgaaaaa ctgggtgacc accggcgatc cggcgcgtga gttcaccatg
     9721 attcagtcag caccgctgat gctgctggct gaccctgatg agttcgtgtc cgtacaactg
     9781 gcgtaatcat ggcccttcgg ggccattgtt tctctgtgga ggagtccatg acgaaagatg
     9841 aactgattgc ccgtctccgc tcgctgggtg aacaactgaa ccgtgatgtc agcctgacgg
     9901 ggacgaaaga agaactggcg ctccgtgtgg cagagctgga agaggagctt gatgacacgg
     9961 atgaaactgc cggtcaggac acccctctca gccgggaaaa tgtgctgacc ggacatgaaa
    10021 atgaggtggg atcagcgcag ccggataccg tgattctgga tacgtctgaa ctggtcacgg
    10081 tcgtggcact ggtgacgctg catactgatg cacttcacgc cacgcgggat gaacctgtgg
    10141 catttgtgct tccgggaacg gcgttccgtg tctctgccgg tgtggcagcc gaaatgacag
    10201 aacgtggcct ggccagaatg caataacggg aggcgctgtg gctgatttcg ataacctgtt
    10261 cgatgctgcc attgtccgcg ccgatgaaac gatacgcggg tacatgggaa cgtcagccac
    10321 catgacatcc ggtgagcagt ccggcgcagt aatacgtggt gtttttgatg accctgaaaa
    10381 tatcagctat gccggacagg gcgtgcgcgt tgaaggctcc agcccgtccc tgtttgtccg
    10441 gactgatgat gtgcggcagc tgcggcgcgg cgacacgctg accatcggtg aggaaaactt
    10501 ctggatagac cggatttcga cggatgatgg cggaagctgt catctctggc ttgggcgtgg
    10561 cgtgccgcct gccgttaacc gtcgtcgctg aaggggggat gtatggccat aaaaggtctt
    10621 gagcaggccg ttgaaaacct cagccgtatc agcagaacgg cggtgcccgg tgccgccgca
    10681 atggccatta accgcgttgc ttcatccgcg atatcgcagt cggcgtcaca ggttgcccgt
    10741 gagacaaagg tacgccggaa actggtaaag gaaagggcca ggctgaaaag ggccacggtc
    10801 aaaaatccgc aggccagaat caaggttaac cggggggatt tgcccgtaat caggctgggt
    10861 aacgcgcggg ttgtcctgtc ccgacgcagg cgtcgtaaaa aggggcagcg ttcatccctg
    10921 aaaggtggcg acagcgtgct tgtggtggga aaccgtcgta ttcccggcgc gtttattcag
    10981 caactgaaaa atggccgatg gcatgtcatg cagcgtgtgg ccgggaaaaa ccgttacccc
    11041 attgatgtgg tgaaaatccc gatggcagtg ccgctgacca cggcgtttaa acagaatatt
    11101 gagcggatac ggcgtgaacg tcttccgaaa gagctgggct atgcgctgca gcatcaactg
    11161 aggatggtaa taaagcgatg aaacatacag aactccgtgc agccgtactg gatgcactgg
    11221 aaaaacatga caccggggcg acgctttttg atggtcgccc cgctgttttt gatgaggagg
    11281 attttccggc agttgccgtt tatctcaccg gcgctgaata cacgggcgaa gagctggaca
    11341 gcgatacctg gcaggcggag ctgcatattg aagttttcct gcctgctcag gtgccggatt
    11401 cagagctgga ttcgtggatg gagtcccgga tttatccggt gatgagcgat gtcccggcac
    11461 tgtcagattt gatcaccagt atggtggcca gtggctatga ctaccggcgc gacgatgatg
    11521 cgggcctgtg gagttcagcc gatctgactt atgtcattac ctatgaaatg tgaggacgat
    11581 atgcctgtac caaatccagt aatgccggtg aaaggggccg ggaccaccct gtgggtttat
    11641 aaggggaacg gtgaccctta tgcgaacccg ctttcagacg ttgactggtc gcgtctggct
    11701 aaagttaaag acctgacgcc cggcgaactg agcgctgagt cctatgacga cagctatctc
    11761 gatgatgaag atgcggactg gactgcgacc gggcaggggc agaaatctgc cggagatacc
    11821 agcttcacgc tggcgtggat gcccggagag caggggcagc aggcgctgct ggcgtggttt
    11881 aatgaagggg atacccgtgc ctataaaatc cgcttcccga acggcacggt cgatgtgttc
    11941 cgcggctggg tcagcagtat cggtaaggcg gtgacggcga aggaagtgat cacccgcacg
    12001 gtgaaagtca ccaacgtggg acgtccgtcg atggcagaag atcgcagcac ggtgacggcg
    12061 acaaccggca tgacggtgac acccgccagt gcttccgtag tgaaagggca gagcactacg
    12121 ctgaccgtgg cattccagcc ggagggcgca accgacaaga gcttccgtgc ggtgtctgcg
    12181 gataaaacaa aagccaccgt gtcggtcagc ggtatgacca tcaccgtgaa cggcgttgct
    12241 gcaggcaagg tcaacattcc ggttgtatcc ggtaatggtg agtttgctgc ggttgcagaa
    12301 atcaccgtca ccgccagtta atccggagag tcagcgatgt tcctgaaaac cgaatcattt
    12361 gaatataacg gcgtgaccgt cacgctttct gaactgtcag ccctgcagcg tattgagcat
    12421 cttgccctga tgaaacggca ggcagaaccg gcgggatccg acagcaaccg gcaggttact
    12481 gtggaagacg tcatcagaac cggcgcgttt ctggtggcga tgtccctgtg gcataaccat
    12541 ccgaagaaga cgcagatgcc gtccatgaat gaagccgtta aacagattga gcaggaagtg
    12601 cttaccacct ggcccacaga ggcaatttct catgctgaaa acgtggtgta ccggctgtcc
    12661 ggtatgtatg agtttgtggt gaataatgcc cccgaacagg cagaggacgc cgggcctgca
    12721 gagcctgttt ctgcgggaaa gtgttcgacg gtgagctgag ttttgccctg aaactggcgc
    12781 gtgagatggg gcgacccgac tggcgtgcca tgcttgccgg gatgtcatcc acggagtatg
    12841 ccgactggca ccgcttttac agtacccatt attttcatga tgttctgctg gatatgcact
    12901 tttccgggct gacgtacacc gtgctcagcc tgtttttcag cgatccggat atgcatccgc
    12961 tggatttcag tctgctgaac cggcgcgagg ctgacgaaga gcctgaagat gatgtgctga
    13021 tgcagaaagc ggcagggctt gccggaggtg tccgctttgg cccggacggg aatgaagtta
    13081 tccccgcttc cccggatgtg gcggacatga cggaggatga cgtaatgctg atgacagtat
    13141 cagaagggat cgcaggagga gtccggtatg gctgaaccgg taggcgatct ggtcgttgat
    13201 ttgagtctgg atgcggccag atttgacgag cagatggcca gagtcaggcg tcatttttcc
    13261 ggtacggaaa gtgatgcgaa aaaaacagcg gcagtcgttg aacagtcgct gagccgacag
    13321 gcgctggctg cacagaaagc ggggatttcc gtcgggcagt ataaagccgc catgcgtatg
    13381 ctgcctgcac agttcaccga cgtggccacg cagcttgcag gcgggcaaag tccgtggctg
    13441 atcctgctgc aacagggggg gcaggtgaag gactccttcg gcgggatgat ccccatgttc
    13501 agggggcttg ccggtgcgat caccctgccg atggtggggg ccacctcgct ggcggtggcg
    13561 accggtgcgc tggcgtatgc ctggtatcag ggcaactcaa ccctgtccga tttcaacaaa
    13621 acgctggtcc tttccggcaa tcaggcgggt ctgacggcag atcgtatgct ggtcctgtcc
    13681 agagccgggc aggcggcagg gctgacgttt aaccagacca gcgagtcact cagcgcactg
    13741 gttaaggcgg gggtaagcgg tgaggctcag attgcgtcca tcagccagag tgtggcgcgt
    13801 ttctcctctg catccggcgt ggaggtggac aaggtcgctg aagccttcgg gaagctgacc
    13861 acagacccga cgtcggggct gacggcgatg gcacgccagt tccataacgt gacggcggag
    13921 cagattgcgt atgttgctca gttgcagcgt tccggcgatg aagccggggc attgcaggcg
    13981 gcgaacgagg ccgcaacgaa agggtttgat gaccagaccc gccgcctgaa agagaacatg
    14041 ggcacgctgg agacctgggc agacaggact gcgcgggcat tcaaatccat gtgggatgcg
    14101 gtgctggata ttggtcgtcc tgataccgcg caggagatgc tgattaaggc agaggctgcg
    14161 tttaagaaag cagacgacat ctggaatctg cgcaaggatg attattttgt taacgatgaa
    14221 gcgcgggcgc gttactggga tgatcgtgaa aaggcccgtc ttgcgcttga agccgcccga
    14281 aagaaggctg aacagcagag tcaacaggac aaaaatgcgc agcagcagag cgataccgaa
    14341 gcgtcacggc tgaaatatac cgaagaggcg cagaaggctt acgaacggct gcagacgccg
    14401 ctggagaaat atgccgcccg tcaggaagaa ctgaataagg ccctgaaaga cggaaaaatc
    14461 ctgcaggcag attacaacac gctgatggcg gcagcgaaaa aggactatga aacgacactg
    14521 aaaaagccga agcagtccgg cgtgaaggtg tctgcgggcg atcgtcagga agacagtgct
    14581 catgctgccc tgctgacgct tcaggctgaa ctccggacgc tggagaagca tgccggagca
    14641 aatgagaaaa tcagccagca gcgccgggat ttgtggaagg cggagagtca gttcgcggta
    14701 ctggaggagg cggcgcaacg tcgccagctg tctgtacagg agaaatccct gctggcgcat
    14761 aaagatgaga cgctggagta caaacgccag ctggctgcac ttggcgacaa ggttacgtat
    14821 caggagcgcc tgaacgcgct ggcgcagcag gcggataaat tcgcacagca gcaacgggca
    14881 aaacgggccg ccattgatgc gaaaagccgg gggctgactg accggcaggc agaacgggaa
    14941 gccacggaac agcgcctgaa ggaacagtat ggcgataatc cgctggcgct gaataacgtc
    15001 atgtcagagc agaaaaagac ctgggcggct gaagaccagc ttcgcgggaa ctggatggca
    15061 ggcctgaagt ccggctggag tgagtgggaa gagagcgcca cggacagtat gtcgcaggta
    15121 aaaagtgcag ccacgcagac ctttgatggt attgcacaga atatggcggc gatgctgacc
    15181 ggcagtgagc agaactggcg cagcttcacc cgttccgtgc tgtccatgat gacagaaatt
    15241 ctgcttaagc aggcaatggt ggggattgtc gggagtatcg gcagcgccat tggcggggct
    15301 gttggtggcg gcgcatccgc gtcaggcggt acagccattc aggccgctgc ggcgaaattc
    15361 cattttgcaa ccggaggatt tacgggaacc ggcggcaaat atgagccagc ggggattgtt
    15421 caccgtggtg agtttgtctt cacgaaggag gcaaccagcc ggattggcgt ggggaatctt
    15481 taccggctga tgcgcggcta tgccaccggc ggttatgtcg gtacaccggg cagcatggca
    15541 gacagccggt cgcaggcgtc cgggacgttt gagcagaata accatgtggt gattaacaac
    15601 gacggcacga acgggcagat aggtccggct gctctgaagg cggtgtatga catggcccgc
    15661 aagggtgccc gtgatgaaat tcagacacag atgcgtgatg gtggcctgtt ctccggaggt
    15721 ggacgatgaa gaccttccgc tggaaagtga aacccggtat ggatgtggct tcggtccctt
    15781 ctgtaagaaa ggtgcgcttt ggtgatggct attctcagcg agcgcctgcc gggctgaatg
    15841 ccaacctgaa aacgtacagc gtgacgcttt ctgtcccccg tgaggaggcc acggtactgg
    15901 agtcgtttct ggaagagcac gggggctgga aatcctttct gtggacgccg ccttatgagt
    15961 ggcagcagat aaaggtgacc tgcgcaaaat ggtcgtcgcg ggtcagtatg ctgcgtgttg
    16021 agttcagcgc agagtttgaa caggtggtga actgatgcag gatatccggc aggaaacact
    16081 gaatgaatgc acccgtgcgg agcagtcggc cagcgtggtg ctctgggaaa tcgacctgac
    16141 agaggtcggt ggagaacgtt attttttctg taatgagcag aacgaaaaag gtgagccggt
    16201 cacctggcag gggcgacagt atcagccgta tcccattcag gggagcggtt ttgaactgaa
    16261 tggcaaaggc accagtacgc gccccacgct gacggtttct aacctgtacg gtatggtcac
    16321 cgggatggcg gaagatctgc agagtctggt cggcggaacg gtggtccggc gtaaggttta
    16381 cgcccgtttt ctggatgcgg tgaacttcgt caacggaaac agttatgccg atccggagca
    16441 ggaggtgatc agccgctggc gcattgagca gtgcagcgaa ctgagcgcgg tgagtgcctc
    16501 ctttgtactg tccacgccga cggaaacgga tggcgctgtt tttccgggac gtatcatgct
    16561 ggccaacacc tgcacctgga cctatcgcgg tgacgagtgc ggttatagcg gtccggctgt
    16621 cgcggatgaa tatgaccagc caacgtccga tatcacgaag gataaatgca gcaaatgcct
    16681 gagcggttgt aagttccgca ataacgtcgg caactttggc ggcttccttt ccattaacaa
    16741 actttcgcag taatcccatg acacagacag aatcagcgat tctggcgcac gcccggcgat
    16801 gtgcgccagc ggagtcgtgt ggcttcgtgg tgagaacgcc gaagggggaa agatattttc
    16861 cctgcgtgaa tatctccggt gagccggagg cgtatttccg gatgtcgccg gaggactggc
    16921 tgcgggcaga gatgcagggt gagattgtgg cgctggtcca cagccacccc ggtggtctgc
    16981 cctggctgag tgaggctgac aggcggctgc aggtgcagag cgatttgccg tggtggctgg
    17041 tctgccgggg tgagattcat aaattccgct gtgtgccgca tcttaccggg cggtgctttg
    17101 agcacggggt gacggactgt tacacgctgt tccgggatgc ttatcatctg gcggggattg
    17161 agatgccgga ttttcatcgc ggggatgact ggtggcgtca cggtcagaat ctctatctgg
    17221 ataatctgga ggccacaggg ctgtatcagg tgccgttgtc atcagcacaa ccgggcgatg
    17281 tgctgctgtg ctgttttggt tcatcggtgc cgaatcatgc cgccatttac tgtggtgatg
    17341 gcgagctgct gcaccatatt cctgaacaac tgagcaaacg agagaggtat accgacaaat
    17401 ggcagcgacg cacacactcc ctctggcgtc accgggcatg gcgcgcatct gcctttacgg
    17461 ggatttacaa cgatttggcc gccgcatcga ccttcgtgtg aaaacggggg ctgaagccat
    17521 ccgggcgctg gccacacagc tcccggcgtt tcgtcagaaa ctgagcgacg gctggtatca
    17581 ggtacggatt gccgggcgtg atacaggtga aacggaatta tcagcccgtc ttaatgaacc
    17641 gctggcaaat ggtgctgtga tccatatcgt gccgcgtctg gcaggagcca aaagtggcgg
    17701 tgtgtttcag gctgtgctgg gggcggctgt tatggcggtt gctatatgga tgccgggggt
    17761 aggaattatg gcgagtaatc tgctgttttc tctcggtgcc agtatgacgc ttggcggtgt
    17821 tgcacagatg ctggccccta aacccagaac cccccgcaca cagacaacgg ataacggcaa
    17881 acagaacacc tatttttctt cactggataa tatggttgcc cagggcaatg ttctgcccgt
    17941 tctgtacggt gaaatgcgcg tgggatcacg tgtggtatct caggagatca gcacagcaga
    18001 tgaaggtgat ggtggtcagg ttgtggtgat tggtcgctga tgaaaaacgt tttatgtgaa
    18061 accgcctccg ggcggtttta tcgtttatgg agcatgacga atgggtaaag gcagcagtaa
    18121 ggggcatacc ccgcgcgaag cgaaggacaa cctgaagtcc acgcagctgc tgagtgtgat
    18181 cgatgccatc agcgaagggc cggttgaagg tccggtggat ggattaaaaa gcgtgctgct
    18241 gaacagtacg ccggtgctgg acagtgaggg gaataccaat atatccggcg tcacggtggt
    18301 gttccgggcc ggtgagcagg agcagtcacc gccggaggga tttgaatcct ccggctccga
    18361 gacggtgctg ggtacggaag tgaaatatga cacgccgatc acccggacca tcacgtcggc
    18421 aaacatcgac cgtctgcgct ttaccttcgg tgtacaggca ctggtggaaa ccacctcaaa
    18481 gggagacagg aatccgtcgg aagttcgcct gctggttcag atacagcgta acggtggctg
    18541 ggtgacggaa aaagacatca ccattaaggg caaaaccacc tcgcagtatc tggcctcggt
    18601 ggtggtggat aacctgccgc cgcgcccgtt taatatccgg atgcgcagga tgacgccgga
    18661 cagcaccaca gaccagctgc tgaacaaaac gctctggtcg tcatacaccg aaatcatcga
    18721 tgtgaaacag tgctacccga acacggcact ggttggcgtg caggtggact cggagcagtt
    18781 cggcagccag caggtgagcc gtaattatca tcttcgcggg cgcattctgc aggtgccgtc
    18841 gaactataac ccgcagacgc ggcaatacag cggtatctgg gacggaacgt taaaaccggc
    18901 atacagcaac aacatggcct ggtgtctgtg ggatatgctg acccatccgc gctacggcat
    18961 ggggaaacgt cttggtgcgg cggatgtgga taaatgggcg ctgtatgtca tcggccagta
    19021 ctgcgaccag tcggtgccgg acggctttgg cggcacggag ccgcgcatta cctgtaatgc
    19081 gtacctgacc acacagcgca aggcgtggga tgtgctcagt gatttctgct cggcgatgcg
    19141 ctgtatgccg gtatggaacg ggcagacgct gacgttcgtg caggaccgac catcagataa
    19201 ggtgtggacc tataaccgca gtaatgtggt gatgccggat gatggcgcgc cgttccgcta
    19261 cagcttcagc gccctgaagg accgccataa tgccgttgag gtgaactgga ttgacccgga
    19321 taacggctgg gagacggcga cagagctcgt ggaggatacg caggccattg cccgttacgg
    19381 ccgtaacgtc acgaagatgg atgcctttgg ctgtaccagc cgggggcagg cacaccgcgc
    19441 cgggctgtgg ctgattaaaa cggagctgct ggaaacgcag accgtggact tcagcgtggg
    19501 tgctgaaggg cttcgccatg taccggggga tgtcattgaa atctgcgatg atgactatgc
    19561 cggtatcagc accggtggtc gtgtgctggc ggtgaacagc cagacccgga cgctgacgct
    19621 cgaccgtgaa atcacgctgc catcctccgg taccacgctg ataagcctgg ttgacggaag
    19681 tggcaatccg gtcagcgtgg aggttcagtc cgtcaccgac ggcgtgaagg tgaaagtgag
    19741 ccgtgttcct gacggtgttg ctgaatacag cgtatggggg ctgaagctgc cgacgctgcg
    19801 ccagcgactg ttccgctgcg tgagtatccg tgaaaacgac gacggcacgt atgccatcac
    19861 cgccgtgcag catgtgccgg aaaaagagac catcgtggat aacggggcgc actttgacgg
    19921 cgaacagagt ggcacggtga atggtgtcac gccgcccgcg gtgcagcacc tgaccgcaga
    19981 agtcaccgca gacagcgggg aatatcaggt gctggcgcga tgggacacac cgaaggtggt
    20041 gaagggggtg agctttatgc ttcgcctgac cgtggcagcg gatgacggca gtgagcggct
    20101 ggtcagcacg gccaggacga cggaaaccac ataccgcttc aggcaactgg cgctggggaa
    20161 ctacaggctg acagtccggg cggtaaatgc gtgggggcag cagggggatc cggcgtcggt
    20221 atcgttccgg attgccgcac cggcagcgcc atcgcggatt gagctgacgc cgggctattt
    20281 tcagataacc gcaacgccgc atcttgccgt ttatgatccg acggtacagt ttgagttctg
    20341 gttctcggaa aagcggattg cggatatcag gcaggttgaa gccagcgcgc gttatcttgg
    20401 tacggcgctg tactggatag ccgccagtat caatatcaaa ccgggccatg attattattt
    20461 ttacattcgc agtgtgaaca ccgttggcaa atcggcattt gtggaggctg ttggccagcc
    20521 gagtgatgat gcatccggct atctggattt tttcaaagga gagataggga aaacccatct
    20581 ggctcaggag ttgtggacgc agattgataa cggtcagctt gcgcctgacc tggctgaaat
    20641 caggacgtcc attacggatg tcagcaatga aatcacgcag accgtcaata agaaactgga
    20701 agaccagagt gcagcgatcc agcagataca gaaggttcag gttgatacaa ataataacct
    20761 gaacagcatg tgggctgtga agctgcagca gatgcaggac ggacgccttt atatcgcggg
    20821 tattggtgcc ggtattgaga atacccctga cggtatgcag agtcaggtgc tgctggcggc
    20881 ggacaggatt gcgatgatta atcctgcgaa tggcaataca aagccgatgt ttgttgggca
    20941 gggcgatcag atattcatga acgaagtgtt cctgaaatat ctgacggctc ccaccattac
    21001 cagcggtggc aatcccccaa cgttttcact gacacctgat ggtcgacttt ctgcgagaaa
    21061 tgcggatatc agcggtaacg tgaatgcgaa ctccgggacg ctcaataatg tcacgattaa
    21121 ccagaactgt cggattctgg gaaaactgtc agctaaccag attgaaggtg atattgtcaa
    21181 aacggtggga aaagcctttc cgagaaatgg cagttatgcc agcggtacaa taacggtcac
    21241 tgtgtacgat gaccaggctt ttgaccgtca gatagtcgtc ccccccgttc tgtttcgcgg
    21301 tggtaagcat gaaaacttca acagcaacaa ccaacagtca tactggtatt caacctgtaa
    21361 gctgcaggtg ctgaagaacg gacaggaaat ctttcagcaa cccgcgacgg atgtcagcag
    21421 ggtattttca tcagtcattg atatgcctgc cggacacggc catgtcaccc tgactttcaa
    21481 tgtttcttca tatggtgcaa ataactggac gccaacgacc agtatcagcg accttcttgt
    21541 tgtcgtgatg aagaaatcaa cagccggcat cagtatcagt tgaattttaa aacccaaatt
    21601 cgggcaccag aaatggtgcc ttttttattt gtggagtgaa tatggcagta cagatttcag
    21661 gtgtgctgaa agacggtgca ggaaaaccga tacagaactg caccattcag ctcaaagcaa
    21721 aacgtaacag caccacagtt gtggtgaaca cggtggcctc agaaaatccg gatgaagccg
    21781 gacgttacag catggatgtt gagtatggcc agtacagcgt cgccctgctg gttgaaggtt
    21841 ttccgccttc acatgccggg accatcaccg tgtatgagga ttctaagccg gggacattga
    21901 atgattttct gggcgctgca acagaagatg atgtttgtcc ggaggcactg tatcgttttg
    21961 aaaagatggt ggaagaggcg gcacgcaacg ctgaagccgc ctctcagagc gcagcggcag
    22021 caaagaaatc agaaacagca gcggcatcgt ccaggaacgc ggcgaaaaca tcagagacga
    22081 atgcaggtaa cagcgcgaaa gcggcagctt cttcaaaaac agccgcacaa aacgcagcaa
    22141 cagcggcaga acgttcagag acaaatgccc gtgcgtcaga agaagcctcc gcagacagtg
    22201 aagaggcttc ccgccgtaat gcagagtcag ccgctgaaaa tgccggagtc gccaccacaa
    22261 aagcgcggga ggccgcagca gacgcaacaa aggccgggca gaaaaaggat gaggctctgt
    22321 cggcagcgac acgagctgaa aaggcggcag accgcgcaga agccgcagcg gaagtgactg
    22381 cagagccctg tgcgaatata gtgccgccgc tgcctgatgt gtggataccg tttaacgatt
    22441 cactggatat gattacgggt ttttcgccat cttataaaaa gatagttatt ggtgacgatg
    22501 aaataacaat gccaggcgac aagattgtta agtttaaacg tgcttcaaca gcaacgtata
    22561 ttaataagtc cggccaactc aagcttgctg aagttgacga accgcgattt gagcgcgatg
    22621 gcttattgat tgaaggacag aggacaaatt atctgaggaa ctcaaataaa ccagactcat
    22681 ggactgttca ttccgcactg aataaaacat ttggcactga taaacagggg ttcaattatg
    22741 ccacggtgac acccacggaa agtatagtgg gaacaacagg tggctatact gtgcatggtg
    22801 tggttgcagc agacagattc ccgctggcaa gtggtgaatg tttcactttt tcgtgccggg
    22861 ttaaaggcgc taaagcacga tgcaggttaa gagtttcagt tattattggt ggaacagata
    22921 ccttctctgc tgactcttat cttgatctgg atacccggat cgcaacagta agcggtaata
    22981 catcccttat aacagccaaa gctgaacaac agggcgagtg gacctactat gaggccactt
    23041 atacagctaa tacggacatt gataccgtta actgtgcttt ttatatgaca aataaaataa
    23101 gtaatgagac attctatgat gactcaacat taaccatgac gacgccgcaa attgaactgg
    23161 gcaatacggc atcgtcattt attgtaacta caatgccaac aacacgcgca agtgatgtag
    23221 ttactatccc atcgcagaat aacctgtcaa cacggccttt tacggtattg tgcgaagtaa
    23281 gcaggaactg gagtacaccg cccaatgttg cgccaaggat atttgatgtt ggagggcaca
    23341 gtattgatga taattattta tcgctggggt ttgttgcaac aggaaagata agcgccaacg
    23401 taggaatggt tcagccacaa attgcctcag atggagaaag gttcattgtg ggtgtgagag
    23461 ctaaatctga tttatcagta aatgcaatat gcaatggtaa ttatacaaca aaccttaatg
    23521 gtaaaatatt tggagttaca gcaacatcgt accggtttgg tgggcagacc gcagcaggaa
    23581 cgcgtcattt gtttggacac atcagaaatt tcagagtctg gtttaaagaa ttaaatgaca
    23641 ggcaaatcaa ggaggcagta tgaaagattt aactttgaaa tttcctggta acagagagtt
    23701 taaatccttc ctgtcatctc ttgactggga ggaggatgaa gacctccaga ataaactgtt
    23761 agtcgatgaa attggtttca cctacacaga aacaggggta acagaagagg gagaacctgt
    23821 ctgtgtccgg aatgacggtt attttgtcaa cattcgcatt cttgatgact tgtttgatgt
    23881 ttctgtattc tctgattatg tcgtggagct ggaaacaccg cttcgggaat ggagctgaaa
    23941 ggaggaaata atggatataa gccccttact tcatgcactt tgtgctgtgg ctgcgcagat
    24001 actggttggt ctttttaccg gaaactgggc ttacggagcg atagccggtt gtacgttctt
    24061 cattgcgcgt gaacataccc aggcagaata tcgctggatt gaaatgttcg ggcatggcaa
    24121 gcgaatgaat atgccgtggt ggggcggttt tgatccgcga gcttgggatg tggcaagcct
    24181 gatggatttt gctgtgccgg tggtggcgtg tctgctggtc tggctgttgg ttaatcgtgg
    24241 gtgaaaaaag gtgagctgta tatgcaacgg aggaagaaac cccgttgctg gaagccagga
    24301 aaaagtatcg ggtgttgctg tcctcggatg ttgtgttaat tgggtgataa cagatcctgt
    24361 gtatgggagt ttcccttttt gcgtgcgttg atgctggtaa cggcaaacgt catgatgaac
    24421 aaaaccgcga ataagacgac aatcgtcgga gctggtgcgc tgtcgataaa aaaggacaac
    24481 cagacaccag tcattgacac tattaccgat atgccagtcg ccagtaggag cgcaatatga
    24541 aagcgttgtg tcaggagtac cgcaatggcg ccaggcgcaa tgagcagaga aatggagaga
    24601 atgataccta ccgctttcag cgtcgccaca atggtcagag agaccatgca cagcagccca
    24661 taatgcagcc atctcgtatg caaaccgctt acctgcgcct gttgataatc aaagctgaac
    24721 agcaaaaaat cccgccattt tacgctaata acaagtgtaa ccagcccggc aataatcatc
    24781 gtctggatta tatcgccgat ggttatcccg agcatgtcgc cgaaaagaat atggtcaaga
    24841 tgtacgtctg gtttgactgc aatatacaag atcagacctg cggcaaacat gccagaaaaa
    24901 acaatcccca tcactgtatc ttgcttgatt cggctgttgt ctttcaggta tcccgtcgcc
    24961 accgcacaga atactccggc gacgaatgcc cctgtagcca aaggtaaccc cagaatccag
    25021 gcaagcacga tgccaggaaa aaccgcatga ctcatcgcgt cacccatcag tgcccaacct
    25081 ttcaggacca gaaagaccga cagcagcgca cagggtatgg aaactaccag tgaaatcagc
    25141 agtgcgtgac tcataaaggt gaactgcagt ggctccagta ataatgccat catgagcgat
    25201 cctccagcgc cttatgcgca cgccgacgat ttgccaaaag cccatgggtg ggcgcaaaga
    25261 caaatgctaa aagaaacagc agtgtctgcg ccaccacgat gattccacct gtcgcgccgt
    25321 ccagaaagta actgacccac gcgccgagga aactggttac actgccaata gttacagcaa
    25381 tcatgagcag gcggggaaaa cgatcggtta acaaccatgc tgttgcaccg ggagtcacca
    25441 ccagacagat caccagaaag gcaccaaccg tttgcagcgc cgcaacggtc gaaaccgaca
    25501 gcagggtgaa gaagaggagt tttaatctgc ccggatgcaa tccaatagca cgggcgtgat
    25561 tctcgtcgaa aaaggtcacc ataagatctt tccatttgaa aaaaagcacg atgatcgaga
    25621 gaatgccaat gatagtgagt tgcaggatat ccgccggatc gattgccaga atattgccca
    25681 ggacgatggt ctgaatgttc acagatgtcg ggttcaatga caccataaac agccccaggc
    25741 caaaaaagga cgagaagatc agaccgatga tggcatcttc ttttaagcgg gtgcgttggt
    25801 taagaaacag catgctgccc gcagccagtc cgccggaaaa gaaggctccc agagaaaacg
    25861 gaagccccag catatatgcc cccgcaacac ccgggacaat agagtgcgac aacgcatcgc
    25921 caatcagcga ccagcctttt agcatcagat agcatgacag gaaagcgcag agaccgccga
    25981 ccatcgccga gacccacatc gcattgagca tatattcata gctgaagggt tccagtagca
    26041 cgttcatctt tcttccctct gcaccgctga cggtcgatga gccacaaaag ggcgttcatc
    26101 gtcagtaata atgctttctt ccgagccgtt aagtgtgaca tggcgcagta cgccgctaaa
    26161 agccagctct aggttctcgg ctgtaaaagt ggtgtctgtc ggcccgcttg ccaggacggt
    26221 gcctttgacc atgaccgtat aatcgcaaaa tgtcgtgacg gatccgagat tgtgtgttga
    26281 gacaagcatc gttttgcctt ccgcgcgtaa ctccctcaac aggctgatga ttttggcttc
    26341 ggttttcaca tcaacgccag taaaaggttc atccagcagg atcacatcac cctgctgtgc
    26401 aatcgctctc gccagaaaga cgcgtttctt ttgtccaccg gaaagctcgc cgatttgtcg
    26461 atggcgaaaa ttcaccatat cgacacgttc cagcgcatcg gtgacaattt gacgatccct
    26521 ctttttggcg atacgcaaca tacccatatg cccatagcgg cccatcatca ccacatcttc
    26581 caccagtaca ggaaatgacc agtcaacatc ttctgactga gggacgtagg caaccaggtt
    26641 tttctgtaac gcctgtcgcg tgggaatacc cagaacagat atctttccgc tggtcagacg
    26701 cacaaatccc ataatcgctt taaacaacgt cgattttccg gaaccgttta ccccaaccag
    26761 agcggcaata gatccacttg gtactgtgaa ggatgcatcg cgcagtgctg tgtgcccgtt
    26821 acgccaggtg acagtaacat cattaacgac aatgcctgca gattgcatca ttatttctcc
    26881 cttttcccag ctttaattcc ctgtaccagc gtactggtag taaccttaag aaggtcgata
    26941 tacgtcggta ccgggccgtt ttctgtgctc agggaatcga catagagcac accgccgtag
    27001 tgtgcgccgg tttcacgcgc aacctgacgc gctggtttat cggaaatcgt actctcgcta
    27061 aagactgccg ggatatgatt tttcttaact atatcaacaa ccttacgtac ctgctgcggt
    27121 gttccttgtt gatcggcatt aatcggccac agataaagct cttttagccc caaatcgcgt
    27181 gcgagataag aaaaagcccc ttcactggtg accatccatc gctgattctc agggagttcc
    27241 gtaatctgct tacgcagggg ggcaagggtt tgggtaatct tggctttata agtatcggca
    27301 ttgcgttggt aggtttgtgc atttgccgga tcgtatttta tcaacgcatc acgaatatta
    27361 tcgacgtaaa tcagagcatt atctggcgac atccatgcat gggggttagg tttgccctca
    27421 tagggtcctt cggtgatccc tacaggcgtc acacccgaag agacaattac ttctggaacc
    27481 ccattgagat gctggtaaaa gcgttggaac cacaattcca gattcatacc attggcgaga
    27541 atcagttgtg ccccctgcgc acgtttaata tcgccagggg taggctgata ctcatgaatt
    27601 tctgcaccag gcttggttat ggatgagact tctgcagcat ctcccgccac gtttttggcc
    27661 atatccgcga tgatggtaaa tgttgtaatg accttgaatt tttcagttgc acttgcctga
    27721 aatgcgatcg agcaggtgag tgcgagcccc cccaagagca tggttacttt ttttatcgag
    27781 tgcataattt agtacctata gtgagcaaaa ttagaacaaa tatagcaacg gctatgtttt
    27841 atagcacagc ctatacaaaa tgaaaatgat tatcattagc agctttgagg cccaaaacag
    27901 ggattaggtt gtttcctgct ggcgacgcgt tattgaggaa aaagtaaggc agctagtagg
    27961 ctttgaaata acgttttgcg gttggctgat gcaatttcga gagtgcatgt attgaatgat
    28021 ttctagccgt tactgatttt cgtatttttt gtatgggagg atttgcacct ccccccaccg
    28081 agcctccatg actttactcc actgtctcta gggctgctgt gtgccaggag cggaagcagg
    28141 ggggccagag actccttaaa agttgatagc tcgttttgca gggagactta cacggtaagc
    28201 gttattccga agagcttaaa attgaagcag tcaaacgggt tgttgagcgt gtttatgcgc
    28261 tgccatctga ttaatcgacg gaagcagttc cgtttggtct atgatgcagt tgtccggcag
    28321 gcgctctgtg acgcaaaaga acgataggag tagcattgaa gtgaacgagg ttatgcttgt
    28381 cttatattat cctctatttt aaaaacatca gctggttgtg taagagtttt tattgtttta
    28441 tcttgttgac tttgctttta tgaaaacaga gtgattgata caatgaaaac cttaagtggg
    28501 aaagagttta ggaaattatt taatcgttat gagacaggat tctatctaag tgagtttgaa
    28561 tacttaaagg actttgatcc tttgtttcct gaatgcgtag ggaaagaatt aaagttgggt
    28621 tataaacgaa aagttgatgt atggtgcgaa gaggatgctg cgctatatgc agaatttata
    28681 gctacaaaag aaaggctgaa aagaggccgg ttaatcctaa aaataaacca agtgtggtcg
    28741 cgtgtatatc ctgcttatat ttatgcaatt gaagaaagaa taaatgtcag ggcaaagggg
    28801 agagagtcat ttaagtatga aactgtgcaa gaaaaacaat gtaaactttc cataatgtta
    28861 gatggtctga aagaccttga atgtgaaata gctatgattt caagtgagtt tgaaattgaa
    28921 aaacactcta tgcactattt ttatatgatt tttgatattg aacgctatat aaatgactgc
    28981 agttactttg ttttttctgc tgctaaagtt gttaaaggcg tgattcaatg cattggttac
    29041 attgacaaaa ataacaaagc aagttgcgat gaattttatt caggcagcta tgaatgcttg
    29101 gatgatgatc aggaaacact gaactattta aatgaatcat gcgcagaggg tatagacgct
    29161 gataaagatc tcatcaggaa gaatgagtta ttagccttat ccctgaagga attgtatcaa
    29221 cttctcgttt caaaaaaata acaagtaata cggcgagcga tatgacgtgc catgggatat
    29281 ccgcacccag cagcatgttg tctccacgat gtccgcagtt cgctcataat agacattcac
    29341 tacagttata gtagaaggta tgcatgctgc tgagtgggga aagtgtgaaa gaaaagaaga
    29401 cagctgcttt gtttgtcgtc acgtttatct tcattggcta tgcaagtcgt aatacaaggc
    29461 gggacaaaac tgagacacat aaggcctcgc aatggcttgc aaggccacac atgtattgag
    29521 atgttaataa aatgtagact tgtaattttg atataaatgg tagagaaaat ctttccccaa
    29581 aataaaaacg aacgtcaatg aaatcaaacg gttgaataaa gttgattttg gctaatacaa
    29641 agacaagaaa ataatattta tgattaaata tcagcgagtt gaatacataa tttttatata
    29701 ctgctgcgcc acatgggttg gactgaagcc gcagacctga ttgttaaagg tatggaaggc
    29761 gcaatcaatg c
//
LOCUS       DAPOXO010000065        29636 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPOXO010000065 DAPOXO010000000
VERSION     DAPOXO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29636
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.065"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1848)
                     /gene="traD"
                     /locus_tag="ROH59_003344"
     CDS             complement(<1..1848)
                     /gene="traD"
                     /locus_tag="ROH59_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001577029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HDX4805787.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILVGLI
                     LWVKISWQTFVNGCIYWWCTTLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLATVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVA
                     RMLKKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARQRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGDPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQARP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQMASLFEPEVASGEDVTQA"
     gene            complement(1899..2636)
                     /locus_tag="ROH59_003345"
     CDS             complement(1899..2636)
                     /locus_tag="ROH59_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805788.1"
                     /translation="MTSDNIAEYVGENNQFTEKPVTEYPPVIQDNTVTTKDYLYSNNI
                     DTDLLVVIGGLIVILFLMMLIMYFINSLRHKELTEILEKISFPEKSGSNLLKPEAVSC
                     NLLSLCVLAPVLCTPRKLAEVSREIIVASAQEIAWTPGSSRIDGHQGENITWSLSSQS
                     PADKYDLINKTSRVSPDSGRFYEPDTVLDHRERVRLFIQIQFPHGSDWSEVLRLTDIV
                     TEKVSSGRAAGGYHHRHTGYTWSVSVN"
     gene            complement(2839..3570)
                     /locus_tag="ROH59_003346"
     CDS             complement(2839..3570)
                     /locus_tag="ROH59_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HDX4805789.1"
                     /translation="MKMKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIW
                     LEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKAD
                     KMDLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVE
                     DVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNAN
                     KVNLKFEEAKPVLEDQLAKSIANIL"
     gene            complement(3619..4104)
                     /locus_tag="ROH59_003347"
     CDS             complement(3619..4104)
                     /locus_tag="ROH59_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface exclusion protein"
                     /protein_id="HDX4805790.1"
                     /translation="MIMRCLTHITLVTVIQFIACYLAGWGNAETIFMLFFIVLWQGLF
                     IWLFSQIRKKRNVSDEFKFSKGVWYITIPVSSLLSPLLSLMVFIIGTLYELRRVSGCV
                     SVREWMQSQVNEQTNEDLHLDFDNMDFHRTNPATGLPMSGIGVDIGGNSYGYSSKRYD
                     E"
     gene            complement(4120..6942)
                     /gene="traG"
                     /locus_tag="ROH59_003348"
     CDS             complement(4120..6942)
                     /gene="traG"
                     /locus_tag="ROH59_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HDX4805791.1"
                     /translation="MNEVYVIAGGEWLSNNLNAIAAFMGTRTWDSIEKIALTLSVLAV
                     AVMWVQRHNVMDLLGWVAVFVLISLLVNVRTSVQIIDNSDLVKVHRVDNVPVGLAMPL
                     SLTTRIGHAMVASYEMIFTQPDSVTYSKTGMLFGAELVSKSTDFLSRNPEIANLFQDY
                     VQNCVMGDIYLNHKYTLEELMASADPYTLIFSRPSPLRGVYDSNNNFVTCKDASVSLK
                     DKLNLDTQSGGKTWHYYAQQLFGGRPDPNLLFSTLIGDSYSYFYGSSKSASQIIRQNV
                     TINALKEGITSYAARNGDSASLVNLATTSSMEKQRLAHVSIGHVAMRTLPMTQTILTG
                     IAIGIFPLLVLAAVFNKLTLSVLKGYVFALMWLQSWPMLYAILNSAMTFYAKQNGAPV
                     VLSEISQIQLKYSDLASTAGYLSMMIPPLSWMMVRGLGAGFSSVYSHFASSAISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATATQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAAAQQEMAREASNRAESALHGFSSSIASAWNSLSQFGSNRG
                     SSDSVTGGADSTMSAQDSMMASRMRSAVESYAKAHNISNEQATQELASRSTRTSAGMY
                     GDAHAEWGVKPKILGVGGGLGVRGGGRAGIDWEDNDAHTASSNTQSSHNARHDIDARA
                     TQDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQVQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIEQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSVRGEENIVRGQYSELQNHHKTEALSQNNKYNEEKSA
                     QERMPGADSPQELMKRAKEYQDKYKQ"
     gene            complement(6939..8312)
                     /locus_tag="ROH59_003349"
     CDS             complement(6939..8312)
                     /locus_tag="ROH59_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HDX4805792.1"
                     /translation="MLRIKPLLVLCAALLTVTPAASADVNSDMNQFFNKLGFASNTTQ
                     PGVWQGQAAGYAYGGSLYARTQVKNIQLISMTLPDINAGCGGIDAYLGSFSFINGDQL
                     QRFVKQIMSNAAGYFFDLALQATVPEIKTAKDFLQKMASDINSMNLSSCQVAQGIVGG
                     LFPQTQVSQQKVCQDIAGESNIFADWAASRQGCTVGGQSSSVRDKASDKDKERVLKNI
                     NIIWDSLSKNRMLDGNKELKEFIMTLTGTLIFGEDSEITPLPARTTDRDILRAIMEGG
                     TAKVYHCNDSDKCLKVVADANVTIARDKALKSQITKLLTSIQNKAVSDTPLDDREKGF
                     ISSTTVPVFKYLIDPQMLGVSSSVVYQLTDYIGYDIMLQYIQELLQQARAMIATGNYP
                     QTVLDSVLENLNQAQQQIAVFQGQVKVQQDALLVVDRQMSYMRQQLSARMLSRYQNNY
                     HFGGSTL"
     gene            complement(8299..8724)
                     /gene="trbF"
                     /locus_tag="ROH59_003350"
     CDS             complement(8299..8724)
                     /gene="trbF"
                     /locus_tag="ROH59_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001323332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HDX4805793.1"
                     /translation="MNHRKYQRKLIMKEKRNDAELKNRKTKRDYDYERRVSDIYFDLF
                     FVFVAAGTFLWVIMHSIFDACIDSWKADPELNNFRYMWNILMYVIPYTLWAFAGGFLI
                     VYVRNPLNELINGGIRIFRLKRRMRRENKLREGGNNASH"
     gene            complement(8672..9019)
                     /gene="trbJ"
                     /locus_tag="ROH59_003351"
     CDS             complement(8672..9019)
                     /gene="trbJ"
                     /locus_tag="ROH59_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="HDX4805794.1"
                     /translation="MPPVLWRGWIPFCRCTERKKVRNKQVVLLIAGISGIATGIIVSL
                     NIPFIRQGLFYPASPVEIVVSLCLTFSVSVVFFVGAIVGWISVSEIYYSRMNGLNESS
                     EISEETYNERKKK"
     gene            complement(8949..9494)
                     /gene="trbB"
                     /locus_tag="ROH59_003352"
     CDS             complement(8949..9494)
                     /gene="trbB"
                     /locus_tag="ROH59_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HDX4805795.1"
                     /translation="MSLTKLLPVILLMMATGVQASTRDEIERLWNPQGMAVQPAQPAA
                     DTSARTEKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYGFSV
                     FPYTLDGQGDTAFPEALPVPPDVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGATDA
                     ASFMARMDTVLQMYGEEKGAK"
     gene            complement(9481..9765)
                     /gene="traQ"
                     /locus_tag="ROH59_003353"
     CDS             complement(9481..9765)
                     /gene="traQ"
                     /locus_tag="ROH59_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HDX4805796.1"
                     /translation="MISKRRFSLPRLDITGMWVFSLGVWFHIVARLVYSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSLEEREALEARQQAMMEGQQEGGHVSH"
     gene            9846..10181
                     /locus_tag="ROH59_003354"
     CDS             9846..10181
                     /locus_tag="ROH59_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin ArtA"
                     /protein_id="HDX4805797.1"
                     /translation="MKKLSFKEKLEIVRNIIRESLSGNAAFALLVYSLLHSLPIKTFA
                     DLFVTILLFIAIIAVVIWLFLIIYVYFCELFRSHWIAVWFILWSVVINLTIGFGIYDK
                     LAPVISLMK"
     gene            complement(10162..10503)
                     /gene="trbA"
                     /locus_tag="ROH59_003355"
     CDS             complement(10162..10503)
                     /gene="trbA"
                     /locus_tag="ROH59_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HDX4805798.1"
                     /translation="MHTGDLCFFTGASLFIVGVVGYFFTGPNNKGVYLLSSFIFFVVN
                     VISVCMLPDNFLFLCGAVMNQCAVPVVSMAVSTIPVITKFDSFRRMFVCIMLSAIWSG
                     VMWFFIISLVK"
     gene            complement(10517..11260)
                     /gene="traF"
                     /locus_tag="ROH59_003356"
     CDS             complement(10517..11260)
                     /gene="traF"
                     /locus_tag="ROH59_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TraF"
                     /protein_id="HDX4805799.1"
                     /translation="MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAA
                     PRQEPDIMQKLTALQTATKRALYEAILYPGVDNFVKYFRLQNYWTQQAGLFTMSAKKA
                     MLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQL
                     AQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGS
                     VRPLSYGFISQDDLAKQFLNVSEDFKPNF"
     gene            complement(11253..11510)
                     /gene="trbE"
                     /locus_tag="ROH59_003357"
     CDS             complement(11253..11510)
                     /gene="trbE"
                     /locus_tag="ROH59_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbE"
                     /protein_id="HDX4805800.1"
                     /translation="MKVIFTSNRFIDFLIRLLITAIVISPVIIWSWDTVKETTADGIL
                     AAAFVILYSGVLLFILYFCFSALTDLQKPDERKSDERNEDE"
     gene            complement(11537..13387)
                     /gene="traN"
                     /locus_tag="ROH59_003358"
     CDS             complement(11537..13387)
                     /gene="traN"
                     /locus_tag="ROH59_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system mating-pair
                     stabilization protein TraN"
                     /protein_id="HDX4805801.1"
                     /translation="MKRILPLILALVAGMAQADSNSDYRAGSDFARQIQGQGTGSIQG
                     FKPQESIPSYNANPDETKYYGGVTAGGDGGLKNDGTTEWATGETGKTITESFMNKPKD
                     ILSPDAPFIQTGRDVVNRADSIVGNTGQQCSAQQINRSEFTNYTCERDTMVEEYCTRT
                     ASITGDWKYTDEYREVTIPHSQFRFSMNGLKLVFSVTAPVTGTVESASLSVYAAFFFL
                     NSRYTFMNTTFNVGLANGQSDTYPLSGATGLQVTQGQVLTGSGCTANGNCLPHGNGDR
                     KVYESLVSGASTFTLKLRMKVRDKEWVPRVEWVESCPFNKADGVLTGTECSEPGGTKT
                     GVMEGKPWNITQACWAYRDKYVTQSADNGTCQKYVDNPACTLASRQCAFYSDEGTCLH
                     EYATYSCESKTSGKVMVCGGDVFCLDGECDKAQSGQSNDFAEAVSQLAALAAAGKDVA
                     ALNGVDVRAFTGQAKFCKKAAAGYSNCCKDSGWGQDIGLAKCSSDEKALAKAKSNKLT
                     VSVGEFCSKKVLGVCLQKKRSYCQFDSKLAQIVQQQGRNGQLRIGFGSAKHPDCRGIT
                     VDELQKIQFDRLDFTNFYEDLMNNQKIPDSGVLTQKVKEQIADQLKQAGQ"
     gene            complement(13384..14022)
                     /gene="trbC"
                     /locus_tag="ROH59_003359"
     CDS             complement(13384..14022)
                     /gene="trbC"
                     /locus_tag="ROH59_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001733892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HDX4805802.1"
                     /translation="MNRKIFALFALTAGMHLAVHASENVNTPENRQFLKQQENLSRQL
                     REKPDHQLKAWAEKQVLENPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPE
                     EGLKRMLGETRHYGIPATLRGMVNNDLKTTAEAVLSLVKDGATDGVQIDPTLFSQYGI
                     RSVPALVVFCSQGYDIIRGNLRVGQALEKVAATGDCRQVAHDLLAGKGDSGK"
     gene            complement(14031..14336)
                     /locus_tag="ROH59_003360"
     CDS             complement(14031..14336)
                     /locus_tag="ROH59_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805803.1"
                     /translation="MATMDSKYIQHLRKISAVLLRLISRTLKLFPFGLVMVPVILFYF
                     APDSFLAEIIHEWKKADISEQVTLVRLYLKVTFTCAFMAVFLNYLFSDEFMPVNSRK"
     gene            complement(14366..15358)
                     /locus_tag="ROH59_003361"
     CDS             complement(14366..15358)
                     /locus_tag="ROH59_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HDX4805804.1"
                     /translation="MKRSLWLLMLFLLAGHVPAASADSACEGRFVNPITDICWSCIFP
                     LSLGSIKVSQGKVPDTANPSMPIQICPAPPPLFRRIGLAIGYWEPMALTDVTRSPGCM
                     VNLGFSLPAFGKTAQGTAKKDEKQVNGAFYHVHWYKYPLTYWLNIITSLGCLEGGDLD
                     IAYLSEIDPTWTDSSLTTILNPEAVIFANPIAQGACAADAIASAFNMPLDVLFWCAGS
                     QGSMYPFNGWVSNESSPLQSSLLVSERMAFKLHRQGMIMETIGKNNAVCNEYPSPILP
                     KERWRYQMVNMYPDSGQCHPFGRSVMRWETGKNPPNTKKNFGYLMWRKRNCVFL"
     gene            complement(15355..15987)
                     /gene="traW"
                     /locus_tag="ROH59_003362"
     CDS             complement(15355..15987)
                     /gene="traW"
                     /locus_tag="ROH59_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HDX4805805.1"
                     /translation="MRCRGLIALLIWGQSVVAADLGTWGDLWPVKEPDMLTVIMQRLT
                     ALEQSGEMGRKMDAFKERVIRNSLRPPAVPGIGRTEKYSSRLFDPSVRLAADIRDNEG
                     RVFARQGEVMNPLQYVPFNQALYFINGDDPAQVAWMKRQTPPTLESKIILVQGSIPEM
                     QKSLDSRVYFDQNGVLCQRLGIDQVPARVSAVPGDRFLKVEFIPAEEGRK"
     gene            complement(15984..16370)
                     /gene="trbI"
                     /locus_tag="ROH59_003363"
     CDS             complement(15984..16370)
                     /gene="trbI"
                     /locus_tag="ROH59_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TrbI"
                     /protein_id="HDX4805806.1"
                     /translation="MTTTQKTTDVTAPRRSHWWWTVPGCLAMVLLNAAISYGIVRLNA
                     PVTAAFNMKQTVDAFFDSASQKQLSEAQSKALSARFNTALEASLQAWQQKHHAVILVS
                     PAVVQGAPDITREIQQDIARRMRAEP"
     gene            complement(16367..18997)
                     /gene="traC"
                     /locus_tag="ROH59_003364"
     CDS             complement(16367..18997)
                     /gene="traC"
                     /locus_tag="ROH59_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HDX4805807.1"
                     /translation="MSNNPLEAVTQAVNSLVTALKLPDESAKANEVLGEMSFPQFSRL
                     LPYRDYNQESGLFMNDTTMGFMLEAIPINGANKSIVEALDHMLRTKLPRGIPLCIHLM
                     SSQLVGDRIEYGLREFSWSGEQAERFNAITRAYYMKAAATQFPLPEGMNLPLTLRHYR
                     VFISYCSPSKKKSRADILEMENLVKIIRASLQGASIATQTVDAQAFIDIVGEMINHNP
                     DSLYPKRRQLDPYSDLNYQCVEDSFDLNVRADYLTLGLRENGRNSTARILNFHLARNP
                     EIAFLWNMADNYSNLLNPELSISCPFILTLTLVVEDQVKTHSEANLKYMDLEKKSKTS
                     YAKWFPSVEKEAKEWGELRQRLGSGQSSVVSYFLNITAFCKDNNETALEVEQDILNSF
                     RKNGFELISPRFNHMRNFLTCLPFMAGKGLFKQLKEAGVVQRAESFNVANLMPLVADN
                     PLTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSG
                     GFAVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERVRDQLSVMASPN
                     GNLDEVHEGLLLQAVRASWLAKENRARIDDVVDFLKNASDSEQYAGSPTIRSRLDEMI
                     VLLDQYTANGTYGRYFNSDEPSLRDDARMVVLELGGLEDRPSLLVAVMFSLIIYIENR
                     MYRTPRTLKKLNVIDEGWRLLDFKNRKVGEFIQKGYRTCRRHTGAYITITQNIVDFDS
                     DKASSAARAAWGNSSYKIILKQSAKEFAKYNQLFPDQFQPLQRDMIGKFGAAKDQWFS
                     SFLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRREGMSIHEAVWQLAWKKSG
                     PEMASLEAWLEEHEKYRSVA"
     gene            complement(19364..19582)
                     /locus_tag="ROH59_003365"
     CDS             complement(19364..19582)
                     /locus_tag="ROH59_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000556745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805808.1"
                     /translation="MHTFIFLVLIKNINGGGSWNITPMPNTDVCVQVLRTIESHGGRG
                     FGNTGECIEVKTNKPLNNVMDTLNGGGQ"
     gene            complement(19662..20135)
                     /locus_tag="ROH59_003366"
     CDS             complement(19662..20135)
                     /locus_tag="ROH59_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000549571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805809.1"
                     /translation="MHKSEAEKIDSILDEHQQIYRRHNQINNILAYCACIAWIPCIIA
                     AFGVDGIYLKILFAVLACCGAVCFFIFFFTLLPESLMVLSRQSLLQLMRLTEDVPDAR
                     QELLNRLLSGKKLTGRDEQDIRRLWQEKVDAMQESATRQREQDTIRKFTEGNKSE"
     gene            complement(20128..20349)
                     /gene="traR"
                     /locus_tag="ROH59_003367"
     CDS             complement(20128..20349)
                     /gene="traR"
                     /locus_tag="ROH59_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HDX4805810.1"
                     /translation="MSDEADEAYSVTEQLTMTGINRIRQKINVHGIPVYLCEACGNPI
                     PEARRKIFPGVTLCVECQAYQEKQRKHYA"
     gene            complement(20484..20999)
                     /gene="traV"
                     /locus_tag="ROH59_003368"
     CDS             complement(20484..20999)
                     /gene="traV"
                     /locus_tag="ROH59_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system lipoprotein
                     TraV"
                     /protein_id="HDX4805811.1"
                     /translation="MKQISLFIPLLGTLLLSGCAGTSTEFECNATTSDTCMTMEQANE
                     KAKKLEQPADAKPAAASLPRLAEGNFRTTTVRAVTAASPSGSGPVVTALPEQKLLAPR
                     PLFTAAREVKTIIPVSSVASVTPPRPLRTGEQTAALWIAPYIDNQDVYHQPSSVFFVI
                     KPSAWGKPRIN"
     gene            complement(20996..21229)
                     /gene="trbG"
                     /locus_tag="ROH59_003369"
     CDS             complement(20996..21229)
                     /gene="trbG"
                     /locus_tag="ROH59_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000235791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbG"
                     /protein_id="HDX4805812.1"
                     /translation="MATSKKINYPVLYESGITPPLCEVSAPEPDAGGKRIVAYVYKSS
                     RNTVFENPDIVKTCTVRDLKNDFVNCDEKGEGQ"
     gene            complement(21241..21594)
                     /locus_tag="ROH59_003370"
     CDS             complement(21241..21594)
                     /locus_tag="ROH59_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001377845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2689 domain-containing protein"
                     /protein_id="HDX4805813.1"
                     /translation="MTEQTETTEIKMNMRNINAITALSVPGKTMSDDFMHAVLSNCTT
                     RIVLPAPKEFSSESLPHNFNMAAVGVMKEGMSMRLFSSPGHIVVAGQSGGGKSASVKE
                     LIDRIIQKYKEPFDE"
     gene            complement(21548..22138)
                     /locus_tag="ROH59_003371"
     CDS             complement(21548..22138)
                     /locus_tag="ROH59_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HDX4805814.1"
                     /translation="MANNMSSRQACHAARYVVARVLRGLFWCLKYTVILPLATMALMA
                     LFVLWKDNTTPGKLLVKEINFVRQTAPAGQFPVSECWFSSSDSSGRSEIQDICHYRAA
                     DAADYVRETDRSLMQLVTALWATLALMYVSLAAITGKYPVRPGKMKCIRVVTADEHLK
                     EVYTEDASLPGKIRKCPVYLPDDRTNRNNGDKNEHA"
     gene            complement(22128..23555)
                     /locus_tag="ROH59_003372"
     CDS             complement(22128..23555)
                     /locus_tag="ROH59_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraB"
                     /protein_id="HDX4805815.1"
                     /translation="MASINTIVKRKQYLWLGIVVVGAASAIGGVLYLSDVDMSGNGEA
                     VAEQEPVPDMTGVVDTTFDDKVRQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGDD
                     QRRIEKLGQDNAALAEQVKALGANPVTATGEPVPQMPASPPGPEGEPQPGNTPVSFPP
                     QGSVAVPPPTAFYPGNGVTPPPQVTYQSVPVPNRIQRKVFTRNEGKQGTSLPYIPSGS
                     FAKAMLIEGADANASVTGNESTVPMQLRITGLVEMPNSKTYDATGCFVGLEAWGDVSS
                     ERAIVRTRNISCLKDGKTIDMPIKGHVSFRGKNGIKGEVVMRNGKILGWAWGAGFVDG
                     IGQGMERASQPAVGLGATAAYGAGDVLKMGIGGGASKAAQTLSDYYIKRAEQYHPVIP
                     IGAGNEVTVVFQDGFQLKTVEEMALERTQNRAEEDNPESPVPVPPSAESHLNGFNTDQ
                     MLKQLGNLNPQQFMSGSQGGGNDGK"
     gene            complement(23555..24259)
                     /gene="traK"
                     /locus_tag="ROH59_003373"
     CDS             complement(23555..24259)
                     /gene="traK"
                     /locus_tag="ROH59_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HDX4805816.1"
                     /translation="MFGSLFFSCSVMAANGTLAPTVVPMVNGGQASIAISNTSPNLFT
                     VPGDRIIAVNSLDGALTNNEQTASGGVVVATVNKKPFTFILETERGLNLSIQAVPREG
                     AGRTIQLVSDLRGTGEEAGAWETSTPYESLLVTISQAVRGGKLPAGWYQVPVTKETLQ
                     APAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLL
                     AGARMDVYVIRDGEGN"
     gene            complement(24270..24836)
                     /gene="traE"
                     /locus_tag="ROH59_003374"
     CDS             complement(24270..24836)
                     /gene="traE"
                     /locus_tag="ROH59_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HDX4805817.1"
                     /translation="MEHGARLSTSRVMAIAFIFMSVLIVLSLSVNLIQGVNNYRLQNE
                     QRTAVTPMAFNAPFAVSQNSADASYLQQMALSFIALRLNVSSETVDASHQALLQYIRP
                     GAQNQMKVILAEEAKRIKNDNVNSAFFQTSVRVWPQYGRVEIRGVLKTWIGDSKPFTD
                     IKHYILILKRENGVTWLDNFGETDDEKK"
     gene            complement(24858..25169)
                     /gene="traL"
                     /locus_tag="ROH59_003375"
     CDS             complement(24858..25169)
                     /gene="traL"
                     /locus_tag="ROH59_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HDX4805818.1"
                     /translation="MSGDENKLKKYRFPETLTNQSRWFGLPLDELIPAAICIGWGIIT
                     SKYLFGIGAAVLVYFGIKKLKKGRGSSWLRDLIYWYMPTALLRGIFHNVPDSCFRQWI
                     K"
     gene            complement(25184..25543)
                     /gene="traA"
                     /locus_tag="ROH59_003376"
     CDS             complement(25184..25543)
                     /gene="traA"
                     /locus_tag="ROH59_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system pilin TraA"
                     /protein_id="HDX4805819.1"
                     /translation="MNTVLSVQGASAPVEKKSFFSKFTCLNMLRLVRAVIPVAVLMML
                     FPELAMAAGKGDLMAKGQETVKATFGKNSSIVKWIVLAEVLVGAVMYMMTKNIKFLVG
                     FAILSVFIAVGMSVAGF"
     gene            complement(25577..25804)
                     /gene="traY"
                     /locus_tag="ROH59_003377"
     CDS             complement(25577..25804)
                     /gene="traY"
                     /locus_tag="ROH59_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001254388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer relaxosome protein TraY"
                     /protein_id="HDX4805820.1"
                     /translation="MRRRNARGGISRTVSVYLDEDTNNRLIRAKDRSGRSKTIEVQIR
                     LRDHLKRFPDFYNEEIFREVIEENESTFKEL"
     gene            complement(25898..26584)
                     /locus_tag="ROH59_003378"
     CDS             complement(25898..26584)
                     /locus_tag="ROH59_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001589401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDX4805821.1"
                     /translation="MCALDRRERPLNSQSVNKYILNVQNIYRNSPVPVCVRNKNRKIL
                     YANGAFIELFSREDKPLSGESYIRLQVEIFLSSLELECQALGHGSAFCRRFNFHGEIY
                     QIRMENVSFYNDESVVLWQINPFPDYPFFALNQSGSNTNTSDKLTIWNDLSPGTLVVF
                     SFYMLGVGHATIARELGITDRASEDRIKPVKRKIKEFFEHFDLFRVSCIYKGEIDSLL
                     SIIREFYGVK"
     gene            complement(26778..27161)
                     /locus_tag="ROH59_003379"
     CDS             complement(26778..27161)
                     /locus_tag="ROH59_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome protein TraM"
                     /protein_id="HDX4805822.1"
                     /translation="MAKVQAYVSDEIVYKINKIVERRRAEGAKSTDVSFSSISTMLLE
                     LGLRVHEAQMERKESAFNQAEFNKVLLECAVKTQSTVAKILGIESLSPHVSGNPKFEY
                     ANMVEDIRDKVSSEMERFFPENDEE"
     gene            27492..28094
                     /locus_tag="ROH59_003380"
     CDS             27492..28094
                     /locus_tag="ROH59_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001388590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDX4805823.1"
                     /translation="MVLLVVRTTNLLSLFVEWVKLFTDKVTRGGKMKKWMLAICLMFI
                     NEICQATDCFDLAGRDYKIDPDLLRAISWKESRYRVNAIGINPVTGYGSGLMQVDSQH
                     FNELDRYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVSWEAVGAYNAGFRKTERQNQ
                     RRLAYASEVYRIYTGIKSSKGIRIPVTKKSLPEINSVQNN"
     gene            complement(28390..29211)
                     /locus_tag="ROH59_003381"
     CDS             complement(28390..29211)
                     /locus_tag="ROH59_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDX4805824.1"
                     /translation="MRLASRFGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSERY
                     TYIPTINIINKLRDEGFQPFFACQSRVRDLGRREYSKHMLRLRREGNINGQEVPEIIL
                     LNSHDGSSSYQMIPGIFRFVCTNGLVCGNNFGEIRVPHKGDIVGQVIEGAYEVLGVFD
                     KVTDNMEAMKEIHLNSDEQHLFGRAALMVRYEDENKTPVTPEQIITPRRREDKQNDLW
                     TTCQRVQENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWVIAEQFRKWKS"
     gene            complement(29330..29617)
                     /locus_tag="ROH59_003382"
     CDS             complement(29330..29617)
                     /locus_tag="ROH59_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805825.1"
                     /translation="MSTRNIHVNTASYTILVAGREKNTGEEWDVLEFSSLTELKKYRK
                     SHPEKMAFSYSYALSRGVDTQFRHINIAEADHFKQFLRQIKRAGLDIRAIC"
BASE COUNT         7424 a         7927 c         6649 g         7636 t
ORIGIN      
        1 agcctgagtc acatcttctc cggaggcaac ctccggttca aagaggctgg ccatctgacg
       61 accttctgct tcccttgcgg caagtacggc actcagacgg ttctccattt ccgggttgat
      121 gtcacgcgga ataaactccg gagcgacctt cggtcgtgcc tgatatttca gagagagttt
      181 gactgccgga tacggtccgg gcagagtgac atagcaggtc agatccggca gagactgaat
      241 gtcggaataa ctgaccagcg tctgacgctc catatcctta ccggtcgata ccccgtcacg
      301 taccgggtca gcaccgtagg aatactgctc gctggctttc aggtgctctt tctcaccaat
      361 ctcaccggca gcgaactctg caatcttatg gctcggggaa cggaaaaaag cacgggtgtt
      421 catgacgtca aacagcgtgg ccgccgcttt ctcaccgtag atatcttcca gctgggcata
      481 ggactggata ccaaacacat aacagccacc gaacttacgg gcttccggca ggatctccac
      541 cagatccggc agtttgtgta acgtgggtaa ctcatcacag aaaaaccaca cacgacggtt
      601 acggttttct cccattgcca gcagaccacg aatggcaatg gacagccaca tggagatcac
      661 aggcttcagg gaggcatggg tgtcggcgtt cgacgaaata aacagccagc cgtttttctg
      721 atcttcccgg acaccacgca tccagtcacg gatggtgaag ggatcaccgt tatgctcaat
      781 cccctgcagg taacggatgg ctttcacgta gttggtcagc acagcacgga tggaaatcgc
      841 cgttttctca attttctctt ccaccaggtt ggccgccggt gaattacgca ggaaggtacg
      901 cagtttttca attttgatgg aaagcagtgt gtccaccagt ttgctgtagc tgcggttggg
      961 gtcattacgc atcaggtacg ccgcttccgc aaaaatggta cgtcctgaac cctgccagaa
     1021 cgggtcctct tttgtaccca tagggatcag agtatttgcg gtattatcaa aatccggctg
     1081 tgtcaggcac tccttccaca aatcccatgc ggcacagcgg gcatccagcg gattcaggat
     1141 tttatcgatg gagggatcat agtaactttt aacaaattcc cctgaacggt cataaatcac
     1201 caccatatca ccgcgctgac gggcatagtt ggccagacga cggataacct ccgacttacc
     1261 ggccccgacc gtgccgtgca gacagaagtt ctggatttcg gaatcccgga taatcggcag
     1321 gtcgccaatc cggatatcgg agtccttgcc gtcttttttc agcatccggg caacgtcttt
     1381 cggattgtct gtcagctgac gaccacctgt gacttcattt tcgctctgtt gtttaccctg
     1441 acgccccaga atccaggaga caacaaagaa ggtgatcagg caaataacca gtgccacaac
     1501 tgtggccaga acgaatgcgg accatagctg ctctccgcac cagatcatat atttatcatg
     1561 cagtacctgg gcagcgttca tccggaaggt tttgccgtaa tactggatct catatactgg
     1621 ctgggacttg attaaatccc gcatgccttc cagcgtggta caccaccagt aaatacagcc
     1681 gttcacaaac gtctgccagc ttatttttac ccataaaatc agaccaacga gtatccagaa
     1741 aaaaataaac aggcagtaaa gcatgatatt ggcgatctgg ctgaacatgc ggatacgcat
     1801 ggacgcaatc tgaccgccct gggtcatatc ctttgcgtta aaactcatga tgaaactccg
     1861 ggaaaatctg gaacagggca gaaaaggatg atgtggggtt aattcacaga aacagaccag
     1921 gtgtaccctg tatgccggtg gtgatacccg cctgcagccc tgccggaaga gaccttctct
     1981 gtaacaatgt cagtcagtcg caatacttca gaccagtcac tcccgtgcgg aaactggatc
     2041 tgaataaaaa ggcgtacccg ttcacggtga tccagaactg tgtccggttc ataaaaacgg
     2101 ccactgtcag gagaaacacg ggaggtttta ttgatgagat catacttatc ggcaggagac
     2161 tgcgatgaca gagaccaggt aatattttcg ccctgatgac catcaatacg actgctcccc
     2221 ggcgtccatg caatttcctg cgcactcgcc acgatgatct ccctggagac ttctgccagc
     2281 tttctgggtg tacagagtac cggtgccagc acacacaggg acaacaaatt acagctgacc
     2341 gcctccggtt taagcaaatt gctcccggat ttttcaggaa aagatatttt ttccagtatt
     2401 tcagttaatt ccttatgcct gagagaatta ataaagtaca tgataagcat catgagaaac
     2461 aatataacaa taagccctcc gataaccact aaaaggtcag tatcaatatt attgctgtac
     2521 agatagtctt tagtggtcac tgtattatcc tgtatcaccg gggggtattc agttacaggc
     2581 ttctcagtaa attgattatt ctcaccaaca tattcagcga tattgtctga tgtcataatg
     2641 actttctccg gaagatcccg gcttcgccgg caacacttca cggtcgcaca aagaatttgc
     2701 acaaccgctc agtgttttca tatttatttc ggaaacgccg ggaggtgaca aaatttattt
     2761 tgttacatcc cggggttgga caacgagcaa cgcgaggcgt cagcaaggag gccggtcaga
     2821 tcagcctcct gacgaggttc agagaatatt tgcgattgat ttggccagtt ggtcttcgag
     2881 aacaggcttc gcctcttcaa atttcaggtt aaccttgttc gcatttgaaa ccacacgggt
     2941 ctggtattta tgctggttac ctgtttcagt actggtctga attttcgcac ctgatgtgcc
     3001 ctgacgcagg gcggcaacat tatccgttgt caccgttgcc ttagtacgct ctgcaatctg
     3061 tacatccgtg atcatggtat agttcacatc ttccaccatc gcatctgcag ccatacccac
     3121 cagaccagca gcaaggccta caccgagtgt ggcaccggca gaatttgagt tatagccggt
     3181 aataccggca cctaacgctg caccaactgc tgcgccttca taaccacggt tcagccatcc
     3241 ctgagactcc cgcagatcca tcttatcggc cttcagcaca ttcgcctgaa tccagtagta
     3301 ggctttatcc ggagaagtca ccacctgata tccttttgct ttcacagcat cagcaatttt
     3361 gccctgcagc ccactcatgt ctttatcaga cgtgtttttg atctgcagaa ataccgtgcg
     3421 ttcgctggcg ggttcaagcc agatggtctc actcatctga gtcttcacct caaggttacg
     3481 cttcttgatt gctgtgctca tcgcaccaca ccctgaaagg gccagagtgg aactgaccag
     3541 tgcaaccatc atcaattttt tcattttcat caatgttcct tcatattgaa taaaacgtca
     3601 taatatacaa attaagattc actcatcata tcgttttgaa ctataaccat atgaattacc
     3661 accgatatcc acaccaatac ctgacatagg taaccctgtt gcaggattag tacgatgaaa
     3721 atccatatta tcaaaatcca gatgcaaatc ttcattagtt tgttcattta cctgagattg
     3781 catccattct cttacgctta cacaaccact aactcgcctt aattcgtata gtgtaccaat
     3841 gataaaaacc atcaggctta ataatggaga gagtaaggaa gatactggta tcgttatata
     3901 ccaaacgcct ttactaaact taaactcatc cgacacattc cgtttttttc gtatttgaga
     3961 gaacaaccat ataaacagtc cctgccatag tactatgaag aacagcataa aaattgtttc
     4021 ggcattcccc caaccagcca gataacaggc gataaactgt atcaccgtta ccagagtaat
     4081 atgggttaaa catctcatta tcatctccca aaaacagcat tattgcttat acttatcctg
     4141 atattccttt gcccttttca taagttcctg tggactgtca gccccgggca ttctttcctg
     4201 agccgacttt tcttcattat atttattatt ctgagataat gcctctgttt tatggtgatt
     4261 ctgcagttca gaatactgtc ctcttacaat attttcctcg ccacgtacgc tgttctgagt
     4321 atcacctata ttccctttat attctgtgac catattatca acctgatgtt ttacatcatt
     4381 acggatatta ctgtcctgcg ttctttgctc aataatggcc tgatgtccct gatggtcagc
     4441 aataatatcc tgactgccac cacccgaagg tacgctctcc attcctttac caatatcacc
     4501 acgggattcc cgccaggcat tatcaacacc aggctgtacc tgttcctgca caaaagacca
     4561 ggccatcgcc cgacgacgtt ctgcaatctc cggtgaactg gtgtttgtca gaatagcttc
     4621 tgcatcctgt ggcgcgtgtt tcattacata ctgtgcaaac tgttgcgaca ggtcttcact
     4681 catctgccca ctcatgcttt cagtacggga tgccatttca gcatattcat ggctgcgggt
     4741 catattcgtc gtgtactggt cgtaactctg cttcgctgaa ttcagggctg cagacaactg
     4801 atccacacgg gaatcagcat tattgtcagt atggctgccg gactcactga ccttgcgact
     4861 ggtaaagtaa tcgctggcct ctttaaagtc ttgtgtagct ctggcatcga tatcatgacg
     4921 agcattatgg ctcgactgag tattactact tgccgtatgc gcatcattat cttcccaatc
     4981 aataccagcc cgaccaccac ctctaacgcc taatcctcca ccaacaccaa gaattttagg
     5041 tttaaccccc cattcagcat gagcatctcc atacatcccg gcagaagttc tcgtacttct
     5101 ggatgccagt tcctgagtcg cctgctcatt actgatatta tgcgccttcg catagctttc
     5161 cactgcactg cgcatacggc tggccatcat ggagtcctgt gcgctcatcg tgctgtcagc
     5221 accacctgtg acagaatcac tgctcccccg gttagaacca aactggctga gcgagttcca
     5281 ggcactggca atactgctgc tgaacccatg cagggcgctt tctgctctgt tcgacgcctc
     5341 ccgggccatt tcctgttgtg ccgctgcaat ctgacgcgtt gcattgatac caaccggtaa
     5401 ccgggacatc gccccgctcg catccatcac catattaccg tcacgggtct gtgtggcagt
     5461 tgcgccactg ccggtctggt acatcatctg accaaacgac gtggtgctgt tggtgctcca
     5521 gctgaagccg ttcacgtttt ccgtctgcat gttgccgtag gagtaattac cgtcaaccac
     5581 actgcctgcc gcactggcgg tcgggctgat agcagaggaa gcgaaatggc tgtacacact
     5641 ggaaaatccg gccccgagtc ccctgaccat catccaggat aatggcggga tcatcatgga
     5701 aagatacccg gcagtggaag ccagatcgga gtatttcagc tgtatctgtg aaatttctga
     5761 gagcaccacc ggtgcaccgt tctgcttcgc ataaaatgtc atggcactgt tcagaatggc
     5821 gtacaacatt ggccatgact gcaaccacat cagggcaaac acatagcctt tcaggacgga
     5881 cagcgtcagt ttgttgaaga cagccgccag taccaggagc gggaaaatac cgatggcgat
     5941 ccccgtcagg atggtctgcg tcatgggcag tgtccgcatc gccacatgac cgatggagac
     6001 atgtgccaga cgttgcttct ccatcgatga tgtggtggcc agattcacca ggctggccga
     6061 atcaccatta cgtgcggcat aactggtgat cccctccttc agcgcattga tggtgacatt
     6121 ctggcggatg atctggctgg ctgatttact tgagccatag aagtaactgt aactgtcgcc
     6181 aatcagcgta ctgaacaaca ggttcggatc agggcgacca ccaaataact gctgggcata
     6241 ataatgccag gtttttccgc cactctgtgt gtccagattc agcttgtctt tcagcgaaac
     6301 cgacgcgtcc ttacaggtca cgaaattatt attgctgtcg taaacgcccc gcagcggact
     6361 ggggcgggaa aaaatcagcg tgtagggatc agcggaggcc atcagctcct ccagcgtgta
     6421 tttgtggttc aggtaaatat cccccatcac acagttctgc acataatcct gaaaaagatt
     6481 ggcgatttcc ggattgcggg acaaaaagtc ggtgcttttt gataccagtt ctgcgccgaa
     6541 cagcatcccc gttttgctgt aggtgacact gtccggctgg gtgaatatca tctcgtaact
     6601 ggccaccatt gcatgcccga tacgggtcgt cagtgaaagt ggcatcgcca gtccgaccgg
     6661 cacattatcc acccggtgaa ctttgaccag gtcactgtta tcaataatct gcaccgatgt
     6721 acggacatta accagcaggc tgataagcac aaacacggcc acccagccca gcaaatccat
     6781 cacgttgtgc cgctgtaccc acatcacggc caccgcgaga acagacaatg tgagcgcaat
     6841 tttttcgatg gaatcccacg tccgggtccc cataaaggcg gcaatggcgt tcaggttatt
     6901 gcttaaccac tcaccaccgg caatcacata gacttcattc acagcgtgct ccctccgaag
     6961 tgatagttgt tctggtaacg gctgagcatg cgggcggaaa gctgctggcg catgtagctc
     7021 atctgacggt caacaaccag caatgcatcc tgctggacct ttacctgccc ctggaaaacc
     7081 gcaatctgtt gctgtgcctg attcagattc tccagcacac tgtccagcac ggtctgtgga
     7141 tagttcccgg tggcaatcat ggcccgggcc tgctgaagca gttcctgaat gtactggagc
     7201 atgatgtcgt agccgatata gtccgtcagc tggtaaacca cgctgctgga cacaccgagc
     7261 atctgcgggt caataagata tttaaagacg gggacggtgg tgctggaaat gaagcctttt
     7321 tccctgtcat ccagtggagt atcactcacc gctttattct gaatactggt gagcagtttt
     7381 gtaatctgtg atttcagggc tttatcccgg gcgatggtca catttgcatc cgccaccacc
     7441 ttcagacact tgtccgaatc gttgcagtga taaacttttg ccgttccccc ctccataatc
     7501 gcccggagga tatcgcggtc agtggtacgc gccggcaggg gggtaatctc gctgtcttcc
     7561 ccaaaaatca gcgtaccggt gagcgtcata ataaattctt tcagttcttt gttaccatca
     7621 agcatcctgt ttttggacag cgagtcccag atgatattga tgttcttcag cacccgttcc
     7681 ttatctttgt cactggcctt gtcacgaaca gacgatgact gtcctccgac cgtgcagccc
     7741 tgacgggacg cggcccagtc agcaaaaata ttgctctcac cggcaatgtc ctgacagacc
     7801 ttctgctgtg acacctgagt ctgaggaaat aatcctccga caatcccctg cgccacctga
     7861 caggagctga ggttcatact gttaatgtcg cttgccattt tctgcaggaa gtcttttgcg
     7921 gttttgattt ccggcaccgt tgcctgcagg gcaaggtcaa aaaagtaacc ggcagcgttg
     7981 ctcataatct gcttaacaaa acgctgcaac tgatcgccat taataaaact gaacgagccg
     8041 agataggcgt cgatgccgcc acatccggca ttgatatccg gcagcgtcat ggaaatcagc
     8101 tggatatttt tgacctgggt gcgggcatac agggagccac cataggcata cccggcggcc
     8161 tgcccctgcc agacgcccgg ttgtgtggta ttggaagcaa atcccagctt attaaagaac
     8221 tgattcatgt cgctgttcac atccgctgac gctgcgggtg tgaccgtcag taaagcggca
     8281 caaagaacca gaagaggttt aatgcgaagc attattgcca ccctccctta atttgttctc
     8341 ccggcgcata cggcgtttca gccggaatat tctgatcccc ccgtttatta attcatttaa
     8401 agggttcctg acgtatacga taagaaatcc acctgcaaac gcccataacg tatacggaat
     8461 gacatacatc aggatgttcc acatataacg aaaattattt aattccgggt cagctttcca
     8521 cgaatcaata caggcatcaa aaatactatg cataatcacc cataaaaaag ttccggcagc
     8581 aacgaacaca aaaaacagat caaaatatat atcagaaacc ctgcgttcat aatcataatc
     8641 ccgtttagtt tttctgtttt ttagttccgc atcatttctt ttttctttca ttataagttt
     8701 cctctgatat ttccgatgat tcattcagac cgttcatgcg gctgtaatat atttcagaca
     8761 ccgaaatcca tcccacaatt gcccccacaa aaaacacaac agaaacagaa aaggtaagac
     8821 acagcgaaac gacaatttcc acagggctgg cgggataaaa aagcccctga cggataaagg
     8881 ggatattcag gctgacgatt attcccgtcg cgatgccgga tattccggca atgagtaaca
     8941 ccacctgctt atttcgcacc tttttcctct ccgtacatct gcagaacggt atccatccgc
     9001 gccataaaac tggcggcatc cgttgccccc tgcaaaagcg gtaatgcctc aagtgtgttg
     9061 acgttgacca ggaaggtggt cggtgtggcc accggaatat tcgggaagaa ggtctgcatc
     9121 acgtccggtg gcaccggtaa tgcttccgga aaggcggtat ccccctgacc atccagggtg
     9181 tagggaaaaa cggaaaagcc gtactgctgt gccagctgtt tcagtaccgg gtcaaactgg
     9241 tgacagtaag ggcaatgccc ctgcataaac agcaccacct tccagtcggc caggttaacc
     9301 tgcctgccgt tgctgaggcg gaaccagcgg ggagccggct tttctgttct ggctgatgtg
     9361 tctgctgccg gttgtgcagg ctgcacggcc ataccctgcg gattccagag tcgttcaatt
     9421 tcatcccggg tggaggcctg cacacctgtg gccatcatca acaaaatgac cggcagtaat
     9481 ttagtgagag acatgtccgc cctcctgctg cccttccatc atggcctgtt gcctggcttc
     9541 cagtgcctca cgctcttcca ggctgacacg tgcaatccat gcatccagca cctggtatgc
     9601 gccgaacagc acaaggatgg ccgcaatcaa ctccgccaga aaaaaagcca tccagggttt
     9661 gctgtaaaca agacgggcga cgatatgaaa ccagacaccc agggaaaata cccacattcc
     9721 cgtaatatca agccgtggta aagagaatct gcgtttactt atcatgttaa actccggtta
     9781 ttatttacat gagagtattc atgtctgtaa tattcgcgtt tgtgtgatat taatcagagg
     9841 tacaaatgaa aaagttatct tttaaagaaa aactggaaat agtgagaaac atcataagag
     9901 agtcattatc aggtaatgcg gcttttgctt tactggtgta ttcattattg cactccctcc
     9961 ccattaaaac ctttgctgat ttatttgtga cgatactgtt atttatagcg attatcgctg
    10021 ttgtgatatg gctatttcta atcatctatg tttatttttg tgagttattc agaagtcact
    10081 ggatagcagt ctggtttatc ctctggtctg tggtaatcaa cctcactatt ggatttggca
    10141 tttatgacaa attagcacca gtcatttcac taatgaaata ataaaaaacc acatcactcc
    10201 agaccatatg gctgacaaca taatacaaac aaacatcctt ctgaaactgt caaacttcgt
    10261 gataaccggt atggtactga ctgccattga aacaaccggt acggcacact gattcataac
    10321 cgcaccacaa agaaacaaga aattatctgg cagcatacat acacttatga catttactac
    10381 aaagaagata aacgagctca gcagataaac tcctttatta tttggtcctg taaagaaata
    10441 accaacaacc cccacgataa acaggctggc acctgtaaaa aaacacaaat cccctgtatg
    10501 catatataac ctttggttaa aaattcggtt taaaatcttc agaaacgttc aggaactgtt
    10561 ttgccaggtc gtcctgtgaa ataaagccgt atgataacgg gcgaacactg ccctgtttcg
    10621 ggtcaaccag catcatggcc gggaaatatt tcacaccgag gcgctgcgcc tgcccctggt
    10681 cagtccggga atccggcaac agcggattaa tcacgccatc cacggaaacg ggaataacac
    10741 tcagaccata ggtatccctg aagccattaa tgacctgcgc cagctgcccg tcgatggggt
    10801 cctgcccccg gtaaaagaac atgatgccgt agtgttcagc cagtttcgca atggcctgtc
    10861 gctgctgcgc ctggtctgcc gccagctggt tccggaccgt gccgttgtaa tggctgtact
    10921 gcaggttata gtccagttcg ggatgcgcca gcatggcttt tttggcgctc atggtgaaaa
    10981 gcccggcctg ctgagtccag taattctgca gccggaaata tttcacaaaa ttatccacgc
    11041 cgggatacag aatagcttcg tacagcgccc gctttgttgc cgtctgcagc gcggtcagtt
    11101 tctgcataat gtccggctcc tgacgggggg ctgcaggtac tggtttattt tctttttcct
    11161 tcggatttat tttctcgtta taccactgcc agcctgcatc ttttcctgac gccggaaaaa
    11221 taaagcagca gagtaacagt ggcagtaatg ctttattcat cttcattcct ttcatcactt
    11281 tttctttcat caggtttctg caggtcagtc agggcagaaa aacaaaaata cagaataaac
    11341 agaagcacac cggagtaaag gataacgaaa gcagcagcaa gtatcccgtc tgccgtagtt
    11401 tcttttaccg tatcccacga ccagataatt accggggaaa tgacaatcgc tgtaatcaaa
    11461 agccggataa gaaaatcaat aaaacggttc gacgtgaata tgactttcat catttccccc
    11521 ggttattttc cataccttac tgtcctgcct gtttcagctg gtcagcaatc tgctctttca
    11581 ctttctgcgt cagaacgcca ctgtccggga ttttctggtt attcatcagg tcttcgtaga
    11641 agttagtgaa atccagtctg tcgaactgaa ttttctgcag ctcatcaacc gtaatccccc
    11701 gacagtcagg atgcttcgca ctgccaaacc cgatacgcaa ctgcccgtta cgcccctgct
    11761 gctggactat ctgcgccagc ttcgaatcaa actgacagta gctgcgtttt ttctgcagac
    11821 agacacccag cactttcttc gaacagaact ctccgacact gacggtcagt ttgtttgatt
    11881 ttgctttagc cagggccttt tcatcactgc tgcatttggc cagcccgata tcctgtcccc
    11941 agccgctgtc cttacagcag ttgctgtatc cggctgcagc cttcttacaa aatttcgcct
    12001 gaccggtgaa agcacggaca tccaccccgt tcagcgccgc aacatcctta cctgctgcgg
    12061 ccagtgccgc cagctgagaa acggcttcgg caaaatcatt actctgcccg ctctgagcct
    12121 tatcacattc gccatcgaga cagaagacgt ctcccccaca gaccatcact ttcccggatg
    12181 tttttgactc gcaggagtac gtggcgtact catgcagaca ggttccctca tcggaataaa
    12241 acgcgcactg acgtgaggcc agcgtacagg ccggattatc gacatatttc tgacaggtgc
    12301 cgttatctgc ggactgagtg acatatttat cccggtatgc ccagcatgcc tgtgtgatgt
    12361 tccagggttt accttccatc actccggttt tcgtaccacc cggctctgaa cactcagtgc
    12421 ctgtcagcac gccatccgct ttattaaacg gacaactctc cacccactcc acccggggaa
    12481 cccattcttt atcacggacc ttcatcctga gtttcagcgt aaaggtggaa gcaccactga
    12541 caagcgattc atagactttc ctgtcaccat tcccgtgcgg gaggcaatta ccgttagcag
    12601 tacagccact accggtcaga acctgcccct gtgtcacctg caaacctgtc gccccggaca
    12661 gggggtaagt atccgactgc ccgtttgcca ggccgacatt aaaggttgta ttcatgaagg
    12721 tataacggga gttcaggaag aaaaaagcgg cgtatacaga caatgatgca ctttccactg
    12781 taccggttac cggagccgtg acactgaaca ccagtttcag accgttcata ctgaaccgga
    12841 actgtgagtg cggtatcgtc acctcacgat attcatccgt gtatttccag tccccggtga
    12901 tactggcagt ccgtgtgcag tactcctcca ccatcgtgtc ccgctcacag gtatagtttg
    12961 tgaactcact gcggtttatc tgctgcgcac tgcactgctg cccggtgttt cccacaatgc
    13021 tgtcagcccg gttcaccaca tccctgccgg tctgaatgaa cggtgcatcc ggtgacagaa
    13081 tgtctttcgg cttgttcatg aaggactctg tgatggtttt tccggtttca ccggtcgccc
    13141 attccgtggt gccgtcattt ttcaggccgc catccccgcc ggcagtcacg ccaccgtaat
    13201 attttgtctc gtccggattc gcgttatagc tggggatact ctcctgtggc ttaaagccct
    13261 gaatactgcc tgtaccctgc ccctgaatct gacgggcaaa atcagaaccg gcccggtaat
    13321 cactgttgct gtcagcctgt gccatgccgg caaccagagc cagtatcaga ggtaaaatac
    13381 gtttcatttc ccggaatctc ctttccctgc cagtaaatca tgagccacct gccggcagtc
    13441 acccgtggcg gccactttct ccagcgcctg gccgacccgc aggtttcccc ggatgatgtc
    13501 gtatccctga ctgcagaaca ccaccagtgc cggtacactg cgaatgccgt actgtgaaaa
    13561 cagcgtcggg tcgatctgaa caccatcagt cgcgccgtct ttcaccaggg acagcacggc
    13621 ttcagcggtg gtcttcaggt cattgttcac catgccccgc agtgtggccg gaataccgta
    13681 gtgccgggtt tcgcccagca tccgtttcag cccctcttcg ggaatggaaa acgacacaaa
    13741 atacagggca ccctgccggg gtttcccgtc ctgcgaagcc tgctgtttac gaaccagctc
    13801 atccagaaaa tggttatctg aacgctgaag ggggttttcc agcacctgtt tctccgccca
    13861 agctttcagc tgatggtcag gtttctctcg cagttgtctg cttaaatttt cctgctgctt
    13921 caggaactgg cggttttcag gtgtgttcac attttctgaa gcatgaacag caagatgcat
    13981 ccctgctgtc agagcaaaaa gtgcaaatat tttccggttc atgatatttc tcactttctg
    14041 ctatttacag gcatgaactc atcagaaaaa agataattga gaaaaacagc cataaacgca
    14101 catgtaaatg tcaccttcag atataatctg acaagtgtca cttgttctga tatatctgcc
    14161 ttcttccatt catgaataat ttcagcgaga aaactgtcag gtgcaaaata aaataatata
    14221 acgggcacca ttacaagacc aaaaggaaat aattttaatg ttctgcttat cagcctgagc
    14281 agcacagcac ttattttcct gaggtgctga atatatttac tgtccattgt tgccattttc
    14341 atttcctctt attcattaaa atgatttaca ggaatacaca gttacgttta cgccacatca
    14401 ggtagccgaa gtttttcttt gtgttgggcg gattttttcc cgtctcccag cgcatcacac
    14461 tgcgcccgaa cggatggcac tgtccgctgt ccggatacat attcaccatc tgataacgcc
    14521 agcgttcttt aggcaggatt ggggacggat attcattaca gacggcgtta tttttcccga
    14581 tggtttccat aatcatgccc tgacggtgca gcttgaatgc catgcgttca ctgaccagca
    14641 gggaggactg caacggactg gactcattac tcacccagcc attgaacggg tacatactgc
    14701 cctgcgaacc ggcacaccag aacagaacat cgagaggcat attaaaggca ctggcaatgg
    14761 catctgctgc gcaggccccc tgtgctatcg gattggcaaa gatgacagct tccggattga
    14821 gaatggtggt caggctgctg tccgtccagg tggggtcaat ttcagaaaga taagcgatat
    14881 ccaggtcacc accttccaga cagcccagcg atgtgatgat gttaagccag tacgtcagcg
    14941 ggtatttgta ccagtgaacg tgatagaacg ccccgttcac ctgcttctca tcctttttcg
    15001 ccgttccctg tgccgtttta ccaaaagccg gcaggctgaa gcccaggttc accatgcatc
    15061 ccggtgaccg ggtgacgtcc gtcagcgcca tcggctccca gtaaccaatg gccagcccga
    15121 tacgcctgaa cagcggcggc ggtgccggac aaatctgaat gggcatcgac gggttcgccg
    15181 tgtcggggac cttaccctga ctgactttga tactgcccag cgagagcggg aaaatacagc
    15241 tccagcagat atccgtgatc gggtttacaa aacgcccctc acaggcagaa tccgcagatg
    15301 ccgcagggac atgaccggcg agaaggaata acatcagcag ccacaggctt cgcttcattt
    15361 tctgccctcc tctgccggaa taaattccac cttcaggaag cgatcgccgg gaacggcgct
    15421 cacccgtgcc gggacctgat caatgccgag gcgctggcag agcacaccgt tctggtcaaa
    15481 gtaaacacgg ctgtccagag acttctgcat ctccgggata ctgccctgca cgaggataat
    15541 tttgctctcc agtgtgggcg gcgtctggcg tttcatccag gccacctgcg ccggatcatc
    15601 gccattgatg aaatacagcg cctggttaaa aggcacatac tgcagcggat tcatcacttc
    15661 accctgacgg gcaaacaccc gcccttcgtt atcccggata tccgcagcca gtctgacgga
    15721 cgggtcaaac aaccggctac tgtatttctc cgtgcgtccg ataccgggca cggcaggggg
    15781 ccgcagactg ttacggatca cccgctcctt aaaggcatcc attttccggc ccatctcacc
    15841 ggactgctcc agcgccgtca ggcgctgcat gatcaccgtc agcatgtccg gctcctttac
    15901 cggccacaga tcgccccagg tgccaagatc ggcggcgacc acactctgcc cccatatcag
    15961 cagggcaatc agcccccggc atctcatggt tccgccctca ttcgccgggc aatatcctgc
    16021 tggatttccc gggtgatatc cggtgccccc tgtaccacgg caggcgacac cagaatgacc
    16081 gcgtggtgtt tctgctgcca tgcctgcagg ctggcttcca gtgccgtgtt aaaacgcgct
    16141 gaaagggctt ttgactgtgc ttctgacagt tgtttctgac tggcgctgtc aaaaaacgca
    16201 tccacggtct gtttcatgtt gaaggcggca gtcaccggtg cgttcagtct gacaatgcca
    16261 taactgatgg ctgcgttcag taacaccatt gccaggcatc ccggcacggt ccaccaccag
    16321 tggctgcgtc ggggggctgt aacgtcagtc gttttttgcg ttgtggtcat gcaacactcc
    16381 tgtatttctc atgttcttcc agccaggcct ccagcgaagc catctccggc cccgatttct
    16441 tccacgccag ctgccacacc gcctcatgaa tactcatacc ctctctgcgt ttctgctgca
    16501 caaactcaaa atccgggccg tcagagctgt acatggcacg gcttaacggg tccacaaaca
    16561 gacggtgcca ggaggaatgg ttttccacct gcagcaggaa ggaactgaac cactggtctt
    16621 tggccgcacc aaacttacca atcatgtcgc gctgcagtgg ctggaactga tccgggaata
    16681 actggttata tttcgcgaac tccttcgcac tctgtttgag gataattttg taggaggagt
    16741 taccccatgc cgcacgggct gcgctggatg ccttgtcaga gtcaaagtcg acgatgttct
    16801 gtgtgatggt gatataggca ccggtatgac ggcgacaggt gcggtaacct ttttgaataa
    16861 actcaccaac tttacgattt ttgaagtcca gcagacgcca gccttcatca atgacgttca
    16921 gtttcttgag ggtacgcggc gtgcggtaca tccggttctc gatgtaaatg ataaggctga
    16981 acatcaccgc aaccagcagt gacggacggt cttccagccc acccagctcc agcaccacca
    17041 ttctggcatc atcccgcagg gacggctcat cagagttaaa ataccggcca taagtgccgt
    17101 tggcagtgta ctggtcaagc agcacaatca tttcatccag acggctgcgg atggtcggtg
    17161 acccggcata ctgctcgctg tcactggcgt ttttcaggaa atccaccacg tcatcaatac
    17221 gtgccctgtt ctctttggcc agccaggagg ccctgaccgc ctgcagcagc agaccttcat
    17281 gcacttcatc caggttaccg ttggggctgg ccatcactga caactggtca cggacacgct
    17341 ccgctgactg gtcaatatcg gtgatgttcg caaacgggtt aaaacgcagg gtttcaccgt
    17401 ccagatatac gccacccatg ttctcacaca gggacttgta gccatccccc atgtcgaaca
    17461 ccacggcaaa gcccccggag tccagcacgc tgcggataag tggctgtatc agcccggttt
    17521 taccggcccc ggaggtgcca cagaccgcca tgttgtagtt ggtgttattc atcccccgga
    17581 agaaaatatc gataaacgcc agctggttac ggtaggtggg tgccagcaga cctgccggtg
    17641 tcagggggtt atccgccact aacggcatca ggttggcaac attaaagctc tctgcgcgct
    17701 gaaccactcc ggcctctttc agctgtttaa acaacccttt cccggccata aagggcagac
    17761 aggtcaggaa attgcgcatg tggttaaagc gcggtgaaat cagctcaaaa ccgtttttac
    17821 ggaagctgtt caggatgtcc tgctccactt ccagcgccgt ttcattgttg tccttgcaga
    17881 atgctgtgat gttgaggaag taggacacga cagaagactg accggagccc agacgctgac
    17941 gcagttcccc ccactccttc gcctctttct ccacggacgg aaaccatttg gcataggagg
    18001 tcttcgactt tttctccagg tccatgtact tcaggttggc ttcgctgtgg gttttcacct
    18061 ggtcttccac caccagagtc agcgtcagga tgaacggaca ggagatggac agttccgggt
    18121 tcagcaggtt gctgtagttg tcggccatat tccacaggaa ggcgatttcc gggttacggg
    18181 ccagatggaa attcaggata cgggccgtgc tgttcctgcc gttctcacgc aggcccagcg
    18241 tcaggtaatc agcccggaca ttcaggtcaa aactgtcctc cacacactga taattcagat
    18301 cagaatacgg gtccagctga cgtcttttcg ggtacaggga gtccgggtta tggttaatca
    18361 tctccccgac aatatcgata aaggcctgtg catccaccgt ctgtgtggcg atactggccc
    18421 cctgtaacga cgcccggatg attttcacca ggttttccat ttccagaatg tcagcccggc
    18481 tttttttctt cgagggagaa cagtacgaga taaatacccg gtaatggcgc agggtcaggg
    18541 gcagattcat cccctccggc agcggaaact gtgtcgctgc cgctttcata taataggccc
    18601 gggtaatggc gttaaaccgt tcagcctgtt cacctgacca ggagaactca cgcagcccgt
    18661 actcaatcct gtcaccaacc agctgactgg acatcagatg gatacacaac ggaataccgc
    18721 gcggcagttt ggtgcgcagc atgtgatcga gtgcctccac aatggactta ttcgccccat
    18781 tgatgggaat ggcttccagc ataaagccca tcgtggtgtc attcatgaac agaccggatt
    18841 cctggttgta atcacggtac ggcagcagac ggctgaactg cgggaagctc atttcgccca
    18901 gaacttcatt ggcctttgcg gattcgtcag gcagtttcag tgctgtgacg agggagttaa
    18961 ccgcctgagt gacggcctca agtgggttat tactcatatg agtattcctt agtgcgttta
    19021 aaaaaggaaa atatcagtct gtggccgtgg atatatcacg cagtgccatt cctgaaacca
    19081 cagcacaaat aagagatgga ggcttttaac aggaaaccag gattaacgtt cctttactga
    19141 atgagcatca tttaatgcct gaagttgttt ttcacgtatc ttatttcgct cattttctct
    19201 tacccgtttc acctctgcca tttcgtttct ttctctacac gctgatgcaa gctcttttgc
    19261 cttaccaaga cttaaacata gccataacgc caacaaatat aaaagccaga acagattcta
    19321 aatatatcga cttcatttca ttttcctttg aagcagtaag cactcattgc ccaccaccat
    19381 tcagtgtatc catcacgttg ttcaaaggtt tatttgtttt aacttcaata cattcccctg
    19441 tatttccaaa tcccctgcct ccgtgtgact cgattgtccg aagaacctgc acgcatacgt
    19501 ccgtatttgg catgggtgta atattccagc ttccgccacc gttaatattt tttatcagca
    19561 caagaaaaat aaaggtatgc attctttatt atctccgctt gtatattaat cactgaatat
    19621 cccttcagtt aacttatgag gtcataaaac actgcagatt ctcattcgga tttattccct
    19681 tcagtaaact tccgaatagt atcctgttca cgctgacggg tggcagactc ctgcattgca
    19741 tccactttct cctgccagag acgccggata tcctgttcat cccgaccagt cagtttttta
    19801 ccggacaaca aacggttaag cagttcctgt ctcgcatccg gtacgtcttc agtcagacgc
    19861 ataagctgaa gcaggctctg acggctgagg accatgagtg attccggcag gagagtgaag
    19921 aagaaaataa aaaagcatac cgcaccacag caggcaagga ccgcaaacag gattttcaga
    19981 tatataccat caacgccgaa cgcagcaata atacagggaa tccatgcaat acacgcacaa
    20041 tacgccagga tgttatttat ttggttatgt ctgcgatata tctgttgatg ttcatccaga
    20101 atagaatcta ttttttcagc ttctgattta tgcatagtgt tttctctgtt tttcctgata
    20161 cgcctgacat tcaacacata acgtcacacc gggaaatatt ttccgccggg cttccggaat
    20221 aggatttccg catgcctcac agagataaac aggaatacca tgaacattta ttttctggcg
    20281 tatacggttt attcctgtca tggtcagttg ttctgtcact gaatatgctt catcggcttc
    20341 atcactcacg gaatattcct cccgacatgt tctgacacgc taccgcccat cccttttcac
    20401 gcacagggca ctcgttttac aggcagattt tgaatacaga aagcccgccg gcattgccgg
    20461 ctgatataca acttcagggc cagttaatta atacgtggtt ttccccacgc agacggttta
    20521 ataacaaaaa acacactgga tggttgatga taaacatcct gattatcaat ataaggcgct
    20581 atccataatg ctgccgtctg ctcacccgtt cttagcgggc ggggaggtgt taccgacgca
    20641 actgaactga ccggaataat cgttttcact tcccgggcag ccgtaaacaa cggacgtggt
    20701 gccagcagtt tctgctccgg aagtgcagtc actacaggcc cgctgccaga tgggctggcc
    20761 gcggtgacgg cccgcaccgt ggttgtccgg aagttccctt cagccaggcg cggcagtgat
    20821 gccgcagccg gctttgcatc tgcaggctgc tccagctttt tggccttctc attggcctgc
    20881 tccatcgtca tacaggtatc ggatgtggtg gcgttacact caaattccgt actggttccg
    20941 gcacagccgg aaagtaataa ggtccccagc agaggaataa ataaagaaat ctgtttcatt
    21001 gtccctcacc tttctcatcg cagttcacaa aatcattctt caaatccctg accgtacagg
    21061 tttttacaat gtcaggattt tcaaaaaccg tattccgtga tgatttataa acatatgcca
    21121 caatgcgttt cccacccgca tcaggttctg gtgcactgac ttcacataac ggaggtgtta
    21181 ttccggactc atacagcacc ggataattta ttttttttga cgttgccatc agaaaccagc
    21241 ttattcatcg aagggttcct tatatttctg aataattctg tcgattagtt ctttcaccga
    21301 agcagatttt ccgccaccgg attgtccggc aaccacaata tgcccaggag aagaaaataa
    21361 acgcatcgac attccctcct tcatcacacc gacagcagcc atattaaaat tgtgcggcaa
    21421 tgattcagaa ctgaattcct tcggtgcagg aaggacgatt cttgtggtgc agttactgag
    21481 aacagcatgc ataaaatcat ctgacatagt tttacccggt acagaaaggg ctgtaatagc
    21541 attaatatta cgcatgttca tttttatctc cgttgtttct gtttgttctg tcatcaggaa
    21601 gataaacagg gcatttcctg atttttcccg gcagggaagc gtcttccgta taaacttcct
    21661 tcagatgttc atctgcggtt accacccgga tacatttcat ttttccgggt cgcaccggat
    21721 atttcccggt gatcgctgcc agcgagacat acatcagtgc cagtgttgcc cataatgcgg
    21781 tgaccagttg catcagtgac cggtcagtct ccctgacata atctgcagca tcagccgcgc
    21841 ggtaatggca gatatcctgt atttctgatc tgcctgaaga atcagaggaa gaaaaccagc
    21901 attcactgac cgggaactgt ccggcaggtg ctgtttgtct tacgaagtta atctccttaa
    21961 ccagtaattt ccccggcgtg gtgttgtcct tccataaaac aaacagagcc atcagggcca
    22021 ttgtggccag tggcagaatg acggtgtact tcagacacca gaacagtcct cgcagaaccc
    22081 gggcgacaac ataccgggcg gcatggcacg cctgacggga cgacatatta tttgccatcg
    22141 ttgcctcctc cctggctgcc ggacataaac tgctgcggat tcaggttgcc cagctgcttc
    22201 agcatctggt cagtattaaa gccgttaaga tgactttcag ctgatggcgg aacaggaacc
    22261 ggactttccg gattatcttc ttccgctctg ttctgcgtgc gctccagcgc catctcttcc
    22321 acggttttca gctggaagcc gtcctggaac accacggtca cttcgttgcc cgcaccaatc
    22381 ggtatcaccg ggtgatactg ttcggcacgt ttgatgtagt agtcactgag cgtctgtgcg
    22441 gctttcgatg cgccgccacc gatacccatt ttcaggacat caccagcccc gtaagcggct
    22501 gtggcaccca gcccgacagc cggctgggag gcgcgctcca ttccctgacc gataccgtca
    22561 acaaatcccg cgccccatgc ccagccgagg attttgccgt tacgcatcac cacttcgccc
    22621 ttgataccgt ttttaccccg gaagctgaca tgccccttaa tcggcatatc aatagttttg
    22681 ccgtccttca ggcaactgat attgcgggtg cgtacaatgg cacgctcact ggacacatcc
    22741 ccccaggctt ccagccccac aaaacatccc gttgcgtcat acgtcttgct gttcggcatt
    22801 tccaccaggc cggtgatacg caactgcatc ggcaccgtgg attcattacc ggtgactgag
    22861 gcattggcat ccgccccttc aatcagcatg gctttcgcaa aacttcctga cggaatgtac
    22921 ggcagcgatg ttccctgttt tccctcatta cgggtaaaca ccttacgctg tatccggtta
    22981 ggcaccggca cagactggta cgtcacctgt ggtggtggcg tgacaccatt cccgggataa
    23041 aacgccgtcg gcggtggaac agcaacgctg ccctgcggcg ggaaggatac gggggtgttt
    23101 cctggctgtg gttcgccttc cggcccgggc ggtgaggcag gcatctgagg tacaggctca
    23161 ccggtcgccg tgacgggatt agcacccagg gcttttacct gctctgccag ggcggcattg
    23221 tcctgtccca gcttttcaat acgacgctgg tcatcaccgc gctgtttgtt caggacatcc
    23281 agttcacgac ggatttcctc atactgcttc tgcatctgcg ctgccgtcac ctgcatctct
    23341 gtggtggcat gctgacgcac cttgtcatca aaggtcgtat ccaccacacc tgtcatatcc
    23401 ggcacaggct cctgttcagc caccgcctca ccgttaccgg acatgtccac atcagacaga
    23461 tacagtaccc caccaatcgc ggaggctgca ccgacaacca caatccccag ccacaggtac
    23521 tgcttgcgtt tcacaatggt attgatactg gccatcagtt gccctccccg tcacggatga
    23581 catacacatc catgcgcgca cctgccagta actggctggc aggctggctg aacatcacgg
    23641 cacgggttcc cggctgccag aagtcacttt cccggatatt cagggcagac agcgttttat
    23701 tttccacggc aaagcggacc atcttcaggt gattccccgt ccatacggca tctgccactg
    23761 aagacagccc cgccggggcc tgcagggttt cctttgtcac cgggacctga taccagcctg
    23821 cgggtaattt tccgccacgg acggcctggc tgatggtcac aagcagggat tcgtaaggcg
    23881 tggacgtttc ccacgctccg gcttcttctc cggttccgcg caggtcactg accagctgaa
    23941 tggtacgccc cgcgccttca cggggaacgg cctgaatgga aaggttcaga ccacgctctg
    24001 tttccagaat gaacgtaaag ggctttttgt tgacggtggc caccaccaca ccgccggagg
    24061 cggtctgctc attattggtc agggcaccat ccagactgtt cacggcgata atccggtcac
    24121 cgggaacggt aaacagattc gggctggtat tgctgatggc aatactggcc tgaccaccgt
    24181 tcaccattgg caccacggtg ggggccagcg taccgtttgc ggccatcacg ctgcaggaaa
    24241 aaaacaggct gccaaatatt attgccgtat tattttttct catcgtctgt ttccccgaaa
    24301 ttatccagcc aggtcacccc gttttcccgc ttcagaataa ggatgtaatg tttgatatca
    24361 gtgaaaggtt ttgaatcacc tatccaggtt ttaagcacac cacgaatttc cacacggcca
    24421 tactgaggcc agacacgaac actggtctgg aaaaaggctg agttcacgtt atcgttttta
    24481 atacgcttcg cttcttcagc cagaataact ttcatctggt tctgtgcgcc cgggcggata
    24541 tattgcagaa gcgcctgatg tgaggcatcg acggtttctg atgaaacatt cagacggagg
    24601 gcaataaatg acagcgccat ctgctgtaaa taagaggcgt cggcactgtt ctgtgacacg
    24661 gcaaaggggg cattaaatgc cattggcgtc acggcagtgc gttgctcatt ctgaagacgg
    24721 tagttattca ccccctgaat gaggttaaca gagaggctga gaacaataag cactgacata
    24781 aatataaagg cgatggccat tacacgactg gtacttaaac gggcaccgtg ttccatataa
    24841 caatcctggt atcagttcta tttaatccac tgccggaaac acgaatcggg aacattatga
    24901 aaaataccgc gcagcagggc tgttggcata taccagtaaa tcaggtcacg taaccaggaa
    24961 ctgccccgcc cttttttcag ttttttaatc ccgaaataaa ccagaaccgc tgcaccaata
    25021 ccgaacagat atttcgatgt tatgataccc cagccaatac agattgctgc ggggatcagt
    25081 tcatccagtg gcaggccaaa ccagcggctc tggttggtca gtgtttccgg gaaacgatat
    25141 ttcttaagtt tattctcgtc tcccgacatc gttttatttc ctgtcagaat ccggcaacag
    25201 acatacctac tgcaataaat acagagagta tggcaaagcc gaccaggaac ttgatgtttt
    25261 tggtcatcat gtacatgacc gcaccgacca gcacctcagc cagaacaatc catttaacga
    25321 tactggagtt cttaccgaag gtcgccttaa ccgtttcctg acctttagcc atcaggtcgc
    25381 ctttaccagc agccatagct aactcaggga acaacatcat cagaacagca accgggatca
    25441 ctgcacgaac caggcgaagc atattcagac aagtgaattt agaaaaaaac gatttctttt
    25501 caacgggcgc agaagcaccc tgaacactta aaacagtatt catatgattc ctctgattaa
    25561 tattgacaga tgaaaactaa agttctttaa atgttgactc gttctcttcg atcacctccc
    25621 tgaatatttc ttcattatag aaatcaggaa accgtttcag atgatctctg agacggatct
    25681 gaacctctat agttttactt ctaccgctac gatctttggc ccgaataagt cggttatttg
    25741 tatcttcatc gagatacact gaaactgttc tgcttatccc gcctctcgcg ttacgcctcc
    25801 tcactcaatt cacctctgtt tcccgactaa taaaatcatg attgcacaga aaccgacgaa
    25861 aaaaaacacg ccaaaattgg cgcaccttat ttaacattta cttaacacca taaaattcac
    25921 gaattatact taatagcgaa tctatttctc ctttatagat acatgacact ctgaataaat
    25981 caaagtgttc aaaaaattct tttattttcc gtttaactgg tttaattcga tcctcagatg
    26041 ctctgtctgt aatacccaac tctctggcaa ttgttgcgtg accaacaccc agcatataaa
    26101 aagagaaaac aaccaatgtc cctggagaaa gatcattcca tatcgttaat ttatcagaag
    26161 tatttgtatt acttccactc tgatttaacg caaaaaatgg ataatcagga aacggattaa
    26221 tttgccataa aacaacagat tcgtcattat aaaaagaaac attctccatc cttatctgat
    26281 agatttcgcc atgaaaatta aaacgacgac aaaatgcaga gccatgtcca agagcctggc
    26341 attccagttc aagtgatgaa agaaaaattt caacctgcag acgtatataa ctctctccgg
    26401 ataagggttt atcttctctg gaaaagagtt caataaaagc cccattggca taaaggattt
    26461 tccggttttt gttacggaca caaaccggaa cgggagaatt tctgtagata ttctgaacgt
    26521 taaggatgta tttatttaca gattgactgt taagtggcct ttctctacga tccagcgcac
    26581 acataggaac ctccgttaag gattctatgg acagtcgatg cagggagttc agacctccct
    26641 gcatcggcga ttttcagttt caatttttaa cgtggcatta accacgtaat taatataacc
    26701 tttatgcggt taattgtcat caaattgaac cagatcaaaa tcctgttatt tgaagcaaat
    26761 caacttttaa ttccttttta ttcctcatca ttttctggaa agaacctctc catctcagat
    26821 gacaccttat ccctgatatc ttcgaccata ttcgcatatt caaactttgg attcccggaa
    26881 acatgagggc ttagtgactc aatacctaaa atcttagcaa ctgttgactg tgtttttacc
    26941 gcacattcaa gaagtacctt attaaactca gcctgattga acgctgactc tttacgctcc
    27001 atctgagcct catgtacacg aagccctaat tcgagaagca tagtggatat gcttgagaaa
    27061 cttacatctg tacttttagc tccttctgca cgtcttcttt ccacaatttt atttatttta
    27121 tagacaattt cgtcactgac ataagcctgc actttcgcca tatgtatacc tctttatttt
    27181 cttatcgcat caaatttatt tcacatataa aagaatgaca attcatcgat gaatcgaatc
    27241 gtgacgcaag ttacgaaaat tacgattcat gcagcaaatc acatcacgaa ttgaatctag
    27301 agtcaattcg ctttaactcg ttgttttatt attactgatt catctatgag ttgcgttaaa
    27361 ttcattggtg aatcatatgc gattcaccaa tgaatccttt ttataatgta aaataaatta
    27421 aaatacatta tttaaaacat aagttaatga ttcaaatagc aaatcagcaa aaacttgttt
    27481 ttgcgtagtg tgtggtgctt ttggtggtga gaaccaccaa cctgttgagc ctttttgtgg
    27541 agtgggttaa attatttacg gataaagtca ccagaggtgg aaaaatgaaa aaatggatgt
    27601 tagccatctg cctgatgttt ataaatgaga tctgccaggc cactgattgc tttgatcttg
    27661 caggccggga ttacaaaata gatcctgatt tactgagagc aatatcatgg aaagaatccc
    27721 gttaccgggt taatgccatc ggtattaatc cggtaacggg atatggcagc ggactgatgc
    27781 aggtagattc ccagcatttt aacgaactgg accgctatgg aattaaaccg gaacatctga
    27841 caacagatcc ctgcatgaac atttataccg gtgcttatta tctggcaata gcctttaaaa
    27901 aatggggcgt ctcctgggag gccgttggtg catacaatgc cggattcagg aagaccgaac
    27961 gccagaacca gagacgtctt gcctacgcat cagaggttta ccggatttat accgggataa
    28021 aaagcagtaa aggtatccgg attccggtca cgaagaaatc acttccggaa attaacagcg
    28081 tgcagaacaa ttaatcttac agacattgtc agataccggt tatgccgcaa aagcggcatg
    28141 gaaggccaca cacaaaaata tcatatgagt gacaatgctg actggccgaa gccccgcgaa
    28201 gcgggaaccc atcttatata tacccggtaa ctgcgcagcc tcctgccaga ccatttttcg
    28261 cgggcacaat atttacagac aaccggaaag ccgattgatg gaattgaggt atatcagacg
    28321 acacagcgat gccgaagaat gataatataa gtaaagcccc gaaaaatttt cggggcttta
    28381 cttatattat catgacttcc actttctgaa ctgttcggca atcacccata acgccttgtt
    28441 gattcggata tcaccatcaa tacctgtaat ggctcttgtc ctggtatttt taccggaggc
    28501 acttcgcccc gacaatccac cttttatcat attctcctga acccgctgac aggttgtcca
    28561 gagatcgttc tgtttatctt cccgacgacg gggagtaatt atttgttcag gcgtcactgg
    28621 cgttttattt tcatcttcat acctgaccat cagtgcagct ctgccaaata aatgttgctc
    28681 gtcactgtta agatgaattt ctttcatcgc ctccatatta tcagtgacct tatcaaagac
    28741 accgagcact tcatacgctc cctcgataac ctgcccgaca atatcacctt tatgtggaac
    28801 gcggatttcg ccaaaattat ttccgcacac caggccattt gtgcagacaa aacgaaaaat
    28861 tccggggatc atctgataac tggatgaacc atcatgtgaa ttaagcagga taatttcagg
    28921 aacttcctgc ccgttaatat tcccttccct gcgaagacgt aacatatgtt tactgtattc
    28981 tcggcgtccc aaatcacgaa cccgactctg acaggcaaag aatggctgga aaccttcatc
    29041 acgtaactta ttgatgatat tgattgttgg aatatacgta taacgttcac tccgggactc
    29101 atgtttatca ccggaaaata ccgaaggcac gaactgcatt aattcatcat ccgttaaagg
    29161 acgttcacgg cggatggaat tataccgacc aaaacgggaa gctaatcgca taacagctac
    29221 tcctttatga aagaataaat ttaataaaaa atttttccgc ttaatatcat ccctcccgat
    29281 ccccattaac aacattgcaa caatcaggag ggatattcat cacatccggt cagcagatcg
    29341 cccggatatc gaggccggca cgcttaatct gacgcaggaa ctgtttgaag tgatcggctt
    29401 ccgcaatgtt gatatggcgg aactgcgtat ccacaccccg gctgagcgcg tagctatagc
    29461 tgaaggccat cttttccggg tggcttttgc gatatttttt cagctcagtc aggctgctga
    29521 attccaggac gtcccactct tccccggtgt ttttttccct cccggcaaca agaatcgtgt
    29581 acgacgcggt gttaacgtgg atatttcggg tactcatcct gctttctcct ctctct
//
LOCUS       DAPOXO010000066        29365 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.066, whole genome shotgun sequence.
ACCESSION   DAPOXO010000066 DAPOXO010000000
VERSION     DAPOXO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29365
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.066"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            51..1175
                     /locus_tag="ROH59_003383"
     CDS             51..1175
                     /locus_tag="ROH59_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDX4805826.1"
                     /translation="MFQKNKTRKMSLSRALDKYLKTVSVHKKGHLQEFYRVNVIKRHP
                     MADRYMDEITTIDIAGYRDQRLAQINPRTGRQITGNTVRLELALLSSLFNIARVEWGT
                     CRMNPVELVRKPKISNGRDRRLTSGEERRISRYFRDKNQQLYVIFHLALETAMRQGEI
                     LTLRWEHLDLQHGVAHLPETKNGLPRDVPLSRKARNYLQILPQQINGNVFSYTSSGFK
                     SAWRTALLDLKIENLHFHDLRHEAISRFFELGTLNVIEVAAISGHRSLNMLKRYTHLR
                     AYQLVSKLDARRKQTSKISPYFVPYPATVGYRNGLFVVTLHDFDLETRAETRELAISH
                     ASVLLLRTLAQAAQRGERVPTPGELPANIDERVMICPLTN"
     gene            complement(1462..1800)
                     /locus_tag="ROH59_003384"
     CDS             complement(1462..1800)
                     /locus_tag="ROH59_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805827.1"
                     /translation="MKIKQHKEKLEIIRNIIRETLLGNAAIVVLVSMIIVLCRQEWTF
                     ISMLFTGALCLSFVFVFFWFIAIIQVYINELTESKRIKWPFVLLWGISIEGTLVYNVI
                     RLFPELLRIT"
     gene            2062..2883
                     /locus_tag="ROH59_003385"
     CDS             2062..2883
                     /locus_tag="ROH59_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDX4805828.1"
                     /translation="MKTDSTGIAARMMLSLDRERICECLLSHRQLQSTPLQVRYPQGV
                     RDALGIMSEQLSLSVSDLTRILVEDALSEMFLPADNIVRRLLSRMEHIMQAHDISATT
                     MAALLAPWNIRPAVFREPDRLTDYLTGEILAALADWFYLSPEWLNGRVHYPLYRPGDW
                     PATQEIFCRIISARENMDIILWHGFPFAGTHSGEYCGVLLRQKKEINNTIIYPVLSLY
                     PVRMDIEKEGWFQMARKISPDIPVRAVTLTPAQAEYLITGKILPTALFRVPLSPW"
     gene            2985..4187
                     /locus_tag="ROH59_003386"
     CDS             2985..4187
                     /locus_tag="ROH59_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HDX4805829.1"
                     /translation="MMMKKHITRTLIASAVLFSFNSTAATSYFEARNDAMGGTGVASS
                     HYGVAPLANPALLTKSGAKDDFSLLLPSVGAQLSDPGNIADNADKISDDWKAFDRAVD
                     SHSGVPQTAARLKERLQDFRNTHASAQAGVSAVAALPGDTLAAALMLKTLGTVSVDGK
                     VSDADLNYLESIADSGSQDVDKNRLTSQAFARAALITDVGVALATELETAGQKWSLGF
                     TPKFQRVDLFNYNTLIKNYDSSAFKGDRYHNTQNGINADIGASMDLDDNWTLGLVAQN
                     LIPRSIETKEVHGVTETFRIRPQVTTGVSWHNDMFTTALDVDLTPASGFTSDSKRQFA
                     AVGAEFNAWKWAQLRTGYRQNLASNNGSAFTAGIGLSPFDVIHIDVAGLVGTDNNYGA
                     IAQLQFTF"
     gene            4291..4749
                     /locus_tag="ROH59_003387"
     CDS             4291..4749
                     /locus_tag="ROH59_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238171.1"
                     /note="Members of this family include DotD of type IVB
                     secretion systems and TraH of plasmid conjugative plasmid
                     systems, both lipoproteins; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotD/TraH family lipoprotein"
                     /protein_id="HDX4805830.1"
                     /translation="MQKKRITLAGGVAMLCLSGCHLPPDNTAPARKYGAASEVAVTRH
                     AQYQLWEQDTYSAALPSRQPGGSLQAHSGRVSFDWEGDALELLSELARLRGQQFSYSG
                     VRLPLPVSLHVRDMTFADALRLTEAQTAWRAVLSQSAGRLHLSYMPTEKK"
     gene            4746..5582
                     /locus_tag="ROH59_003388"
     CDS             4746..5582
                     /locus_tag="ROH59_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000745049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDX4805831.1"
                     /translation="MKKQVCLLLSGLLLAGCAGQHHRPPAGMAGNLPPPDLRAWLTPT
                     DNQDDGISDTRRQMLTDAGRTLGFRGGKAQRSWELIQALNARESTLNALYDFRPLISR
                     EGWLPPVIDEAQDVAHIQPDQIRTASRVWTILRPERFVSNPPGWRDWLLRGLSTTATP
                     GTEGRVVPEDRAQRRLWENALRQGWQEGRDNADLTLEANQKRLTRDYRGMMLYALLWR
                     QGMITRPDVTEQRQTVTGNGRKLITGDHVRRLKTHAEFTLQKSRWRPVVSTEGAPDEI
                     TR"
     gene            5566..6714
                     /gene="traJ"
                     /locus_tag="ROH59_003389"
     CDS             5566..6714
                     /gene="traJ"
                     /locus_tag="ROH59_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid transfer ATPase TraJ"
                     /protein_id="HDX4805832.1"
                     /translation="MKLPDEFGTFPFARFTAEEFRYFFAWCARHCVSDIDLTGGSPVS
                     VSRFGRRVRSSAHPLPSSIMMALSDELFGREVLPRVLSGHPVDRTIQVSGDASGRYGL
                     QRGQRVRLRCHLIQGTSATEEKVISVTMRVIPSDIPDILTMNIEPDLLDAMLRKTGLG
                     FICGETGSGKSTLAAALYRYIQTHFPDRKTVTYEDPVEYILGGENDLLPPHQAEIGRD
                     VESFAAGLRSAVRRNPDIIGIGEIRDYETADAAVQAGNTGHFCIGTMHTKSPGETFAR
                     LLGLFPPEIRDSMAAATLSLVQFILVQVLVRTNDGGRQAVREYIVITDELRDTLSRQS
                     HATWGHYIDEIIRKEKRRIRDQVLTMYQTGSIEASEAALFIPAGEFPK"
     gene            6711..7001
                     /gene="icmT"
                     /locus_tag="ROH59_003390"
     CDS             6711..7001
                     /gene="icmT"
                     /locus_tag="ROH59_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IcmT/TraK family protein"
                     /protein_id="HDX4805833.1"
                     /translation="MKREGFWRDVTPPLNIYGVPLPFTMIYLLLFPYPSKTTFWVCSG
                     ILLFFVLLGYSGWTVRTLCRRLYSLVQGKQASGRPWWYRHRTELPREWRGTE"
     gene            7233..7814
                     /locus_tag="ROH59_003391"
     CDS             7233..7814
                     /locus_tag="ROH59_003391"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805834.1"
                     /translation="MFYPAVDYLVIILLLAFLMVTLFACIFCLRHEYIRKESEKRKKD
                     FFKKKELNITEFSWFRYNQHNETGINITMDKTIIVMVAVNGRMFSKKYSITSLTFDTK
                     NITEAALYENGIVTRKLTLHRHVSDDRPAGVPSKQPIRTIRLCIRQKDHTDDISFILY
                     QGRLEQRGHNYTIIKGKANSVILLLKMLLTNKI"
     gene            8168..12229
                     /locus_tag="ROH59_003392"
     CDS             8168..12229
                     /locus_tag="ROH59_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDX4805835.1"
                     /translation="MKSRYRTWLAVPPEETEAVKNAVPPLNGRKAVAWDPEKKLWYAR
                     AGTELSLLERWLPRPQELSMDAGDPVTEFAQVLENAGLVIQGLPQMDGAIHRVATRDD
                     KKGAKSGAYRAYLDGRPAGWYRDYRSADDSPTNWVFSGGEQHDPLARLHLRAFAQQQR
                     DDNARKLQQQYNKQAGYARSYINGLPQATAHEYLTRKGIRAAPGVRLNNKNELVIPFS
                     NGRGEIRSYQRIPVTGGKDARILKDSEKTGNWFTFGTPENGRPLLFAEGYATAASLHE
                     ATGLPVLMTVDASNMIAVAENARQIWTDSPFVFCADNDHQREINKGVFSATKAAEVTN
                     GEVIIPAFTEAEKAQGLTDFNDLDASRGRDDFQNAMNAQLKHIGIPTPNSDTADNREA
                     VVIGNLIFTPVKDEKPQMSPENRQSTAPETELATQDTPYDTHSDDTENQAYEDDYAAY
                     ASLQSVTAETLSPDKPLENIASAADTGTENTSAATAGDQEDLNTDATGTDTAHNSDTA
                     ETGTLPEPAGMQSMQQATTEPTAEDKPHENVVSAADTREENASVATADTGEENASATT
                     ADNQSTQAEEHPRSEDTPETSLSDAAGTQHTTTTQSEEQVQVSMASADDWSAFAEDLN
                     ADTPGAPTVHNTDNAETNTVSEPAGMRPVQQVTTELTAEDKAQEKSVASAAETGAEHS
                     SDITDDNRNAPAEELNADATVAVHNTGTAETASPSEPAETQPVRQATAEPTAEDKLQE
                     ERLVSATETSTANEAARPETPSLFSRLRRFLTGVKSRTSEPSVIQEKKPTEAETATEE
                     VAPPSPPETSPEDTSSAEPDTIIFAPRRPDSPQRHNLDEILKNLTHKEFPDRTALYSV
                     DGEPAFLDRLYCLEMVDGASADDKKVLAALAVATNFYGGVIELTGSDAFKQKAMQLIV
                     EYDIKVRMKLPAQRAALEKLRKEKEMAHDAIVTHRPTPELNRQSPEETTMAQPAPPVS
                     PKAEAEQTAGSTAETPHPEAPVTAKAEAPRADRPEHPAAPSSAPEKAPVSAQPQQPDT
                     PEEEPPGKLSPGESVTAVLTNYGEKEYAPGKGRCFFVELTNRSGKREYWGNGLEELVK
                     NHQKGDPVTLTLQARETFRLSGETRDRIRNIWAITPVSNGITVNNDQPHAGQHTLEFP
                     MATFSQVMLQMQQHWPQIMQEVRSPKNPPNNLYIGEDRQPASAPQDQSMRLPLAGNAP
                     NELIPAIASADKDNRQLNLLLVHSADDHLQGVVRLNGTLYPALATPSADNRQLVINAL
                     TDNGLQFAGYGEAVNHDENNHQRPSPQIMQFHLKQQDSPLFAAIHKPEEQPDKLFRSL
                     GFEQTWKEWSDSQKAEDRQEKTLQQAQSHSPGR"
     gene            12246..12596
                     /locus_tag="ROH59_003393"
     CDS             12246..12596
                     /locus_tag="ROH59_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDX4805836.1"
                     /translation="MNMKKTLLVILTGITLASPVAGAATCRAGAAAEAGSRAAWERAR
                     TASQAWSQRENDVASSLQSCLSRIKDISITLPQFPSLDKLLRDLENQVCDAVVDRVND
                     HLPGNIDPWKDYNL"
     gene            12608..13303
                     /locus_tag="ROH59_003394"
     CDS             12608..13303
                     /locus_tag="ROH59_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotI/IcmL family type IV secretion protein"
                     /protein_id="HDX4805837.1"
                     /translation="MSEAQPTSPVSPEADNSGDIYNPVLRTIAQSEQRAALVPGLVRA
                     LLCSGAALCISLVANGIQYWHATGVTREYFATDNGRLVRLAPTSQPAWSQSDVMNFGS
                     MTLSEAFNLDFVHYRKQITTQAPRFSEAGFAGYVNALQASNILDTIKKEKFNLTTTIG
                     AGTLVNQGQMENGVWFWKFQYPVRMRLVGQTSTRPEQAFTFEITVRRVDPRIKPGGME
                     ISQMVSRNAAAGI"
     gene            13314..14288
                     /locus_tag="ROH59_003395"
     CDS             13314..14288
                     /locus_tag="ROH59_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001191879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraN"
                     /protein_id="HDX4805838.1"
                     /translation="MHIHHLIGALLIVCGTVTAADNPGWKNARSPQTGGKTAQATGNT
                     PAGGPPPAAQLPGNLPPPGAALVQEGASLDSPLNAGEIRELRGIMADNERAISAPLTS
                     VVPRISSLTVNLSPGASLPLVRTALHNVSVVTFTDVNGSPWPQSDPPYNAAPGHFDVQ
                     FNGNMVSVTPLRAWAAGNVTVYLKGLSVPVILNITSGETDTTTLSQEIDSRLDLRIPR
                     QGPASPVVSIPSEKIALHDATLQAFLDGVPPDDPAIRRLKFSGNVPDTTIWQHGDDLL
                     VRSRAMLRDEFEQTLASADGTRLWKLPVTPLLTFSVNGQSVHVTPELE"
     gene            14292..15629
                     /gene="traO"
                     /locus_tag="ROH59_003396"
     CDS             14292..15629
                     /gene="traO"
                     /locus_tag="ROH59_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraO"
                     /protein_id="HDX4805839.1"
                     /translation="MSAEQEQDTAEKSGKKLSALLVMGGVIIIGGGYLLLTWLSPENA
                     ASLSSVNINSTTSGGGRNVMETQHYRDLLRADNERGAAEALRNNETFIASLPRGLDTD
                     TGNDQKRDNPPDDQSGTSGQNASPPQEDQTAREKQREALQKLLARINTQHPDARPPVV
                     AAAMWGTTGAPGISSHASPPGTGTSPQPRLQEASLATPAARTGIQLIPALTRVPAFID
                     TEVDSDNAVSRVVASVPAGPWAGAVLYSQDARLAGKGMDIHFDRMMWRGMFLKVNAYA
                     LNEHTGMSSVASDVNHRWFKHIVLPSVLGGAGSVGSLYKDANTQVIQGNYGSITGRVG
                     MPDGRALAGVIAGGMAERGSQLLTRQAESEPYRQVTVSRGEVVSILFVEPVMSNDISP
                     PSSGTAPSVPPPSGRPLTQEEAERQASDRIQAAVIRKQNEMRQRYGIQQESHP"
     gene            15626..16339
                     /gene="traP"
                     /locus_tag="ROH59_003397"
     CDS             15626..16339
                     /gene="traP"
                     /locus_tag="ROH59_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HDX4805840.1"
                     /translation="MKNEHEDPGSFGETTTPASGKSFLKRQYMGYSLPVWAGCVLIIL
                     AAVWYKFLRTPSEPPADAGFAVTPPAAESWAEPMTMTETGGGNNMPAPPVAPQADMQQ
                     LARDLKAELDRRDEEIRRTLTMLKDSITTLSNAIQKDEAWAQETRQLLEETRKQVHTL
                     QMQGALPAPTGNNRQPAKTLPSPLQGMKIMSVEKGMAWIRWQGSAWAVREGDSLGNIT
                     ITRIDPSSRAVITSAGTLR"
     gene            16339..16866
                     /gene="traQ"
                     /locus_tag="ROH59_003398"
     CDS             16339..16866
                     /gene="traQ"
                     /locus_tag="ROH59_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraQ"
                     /protein_id="HDX4805841.1"
                     /translation="MSIDALTAIENFASGIFSAGMEFLFTWGELLGIIGLIGHLMRAR
                     AEGRRSMGPGKFIAGIFICGMLVSLPSMINAGGTQMGFRADSFAPIAYVQPGSFGAAA
                     GAVNAILSLAKLAGVGFVMNGISIWRKSLLDGHTALSASESISKGNVKFVAGVLLVFN
                     DRVIDATLASLGIAF"
     gene            16913..17311
                     /locus_tag="ROH59_003399"
     CDS             16913..17311
                     /locus_tag="ROH59_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001605438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HDX4805842.1"
                     /translation="MSRLRAMAARLRAASVYVQLCLMACRDRLVRLLLLLPVMLLPHT
                     AMANTLFDMIKTVGDGARGSSSSFVAIGQVIGLVLFIGGLLGLKQIGKKPGAGLACLL
                     SILVGVCLAVVPELMGSGQKTLGLSPVSIS"
     gene            17368..17619
                     /locus_tag="ROH59_003400"
     CDS             17368..17619
                     /locus_tag="ROH59_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003665769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraS"
                     /protein_id="HDX4805843.1"
                     /translation="MSCELPPFTLLRTEHGNVIARDNRDNQEFVFAECYSTAIAALIL
                     AAVTLYTERKAYEKDPATHRPGPGTMAFPAPATGHGIQR"
     gene            17534..18352
                     /locus_tag="ROH59_003401"
     CDS             17534..18352
                     /locus_tag="ROH59_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraT"
                     /protein_id="HDX4805844.1"
                     /translation="MKKTPPLIAPVRERWLFPLPQPDTVFSGEALLPPSVLSTEGRCP
                     CCRRTVTHRFILEDSWPLQQMADTCRDTVVLLEKNLTRVMRLKKRPVPENADEKKKHT
                     RTLQDAERSLAQARLSARRLALRHVEKSQIVTTDALSENESDLLQPEGPPFHLCAFCH
                     AWHCLNGYAAAQGVMVWLPDLHPASVVALNARALQEIFSDNRQRVRQGRAVLNALVQN
                     RLAVEEKFRTWRPADFADALRRWPPAQRKTLREKMDGVALILMPDSFPDKKYVM"
     gene            18407..18766
                     /locus_tag="ROH59_003402"
     CDS             18407..18766
                     /locus_tag="ROH59_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805845.1"
                     /translation="MDTLTAGYQFSADSFRRFIIRTLTDDIPPDGDEKEIARFILRHP
                     AFNGGWLLFLAAEIHERSHTHKSITVTVSVDNYLSWMDIAVSGLPELPDMPFCDFFIR
                     RQQFIYPGVPPTKSGEE"
     gene            18766..19146
                     /locus_tag="ROH59_003403"
     CDS             18766..19146
                     /locus_tag="ROH59_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805846.1"
                     /translation="MKIHRISPETLITLIHAHLAGKTDSTAKEEHRLLRRFLRDDDGR
                     LAGVLLNIAGILQFNRELSARHNYPATPLTEFSLRKRGKQLHLCLCSLRFFYIPPVFI
                     RNERRKCIVVHINKITYPPVNSLR"
     gene            19322..22366
                     /locus_tag="ROH59_003404"
     CDS             19322..22366
                     /locus_tag="ROH59_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDX4805847.1"
                     /translation="MNINRIIFAIEDCISTLSRYSVSAFFPDYCDLHTVIGLDQQDRE
                     RRPWLKAPYIATTKQGYYLSVFEISGALKEMDENPDLTAPGTLESLITALAERMNTAW
                     KNSGHKISFVFERDPERGRDEIEAMLLPQRKSIARTGILLQDVLDEKVTTLTPWLVRE
                     RCWLTVWSSEELLSRTDRKDHQTRIRKLAEHAPPARFAQDPWRWTLSALKIRHDALLD
                     TLEQALTHDSDGLLVRLMDIHEVGREIRRQLERNSTPAVWQPHLPEDARPAGWRQGED
                     TSVFHAPSLNLQLFTTQPETHGSLIKAGDLWHGMVAITLPPQNLRTFNQLVRDVPRAI
                     PWRIRMDLMPGGMKALGVKKTLLTYSSFISPLRPMYDSVMMLNDINKHDPVCIMTIVA
                     TTWGNSREVCTRNQALLKSALEGWGVCGTTTTFGDPRRAWVNTVLAASHGSGPVPLYP
                     PLSHALSLFPLNRAGSVWRGQGNLMMHTEDGSAWEVALASSQQNKHTELTPGAPGLGK
                     SVLINALSEIQIASAQKNLPFIAYIDKGFSAQGLVQLIRDSLPEQRKDEAVGIILSND
                     PEHTRNLFDVMYGARKPATPEKNFMVSVLCALCVDTGTGQPCNPGDTRQIISNLVDLA
                     FREYGENNPRLYRAGTEPLVDLALEESGIAEQHDAGWWNAATWFEIRDMLHMAGNIPA
                     AQRAHYQAMPLLAEMSALLGQPSIRDVFGTVQRDNSAELLLDYIRRALDQGHSDYPMM
                     SGCTRFMLSPDTRVVAVDLNNVAGDKTPAGRLRTGIMYLLAGQIAGGDFVLPQYQEEI
                     RKNLDPRYHEVIFRRIEQLDQEVKTKVYDELHNAKGINFIWEALDTQELEQRKFGIRT
                     VLSTQLLQDYPPAVLKSANTLWLLRYRPDEIPFLRDNFGVPEVTLRRFLKMPEGAAPD
                     GSGVPVLAVFRVKNGTLARILKFTLGPLELWALNSSPKDSALRRALTQELGSLRARQI
                     LAEHFPRGSATSLIEHRARTHDSENVIHDLAAELIRKQGYHL"
     gene            22366..22983
                     /locus_tag="ROH59_003405"
     CDS             22366..22983
                     /locus_tag="ROH59_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraV"
                     /protein_id="HDX4805848.1"
                     /translation="MYSIHITPRCRRPARGQVFLKTLRVDGDSFSFTLPSACFTLRPS
                     PNPRVIFASDRRADGEMSGVRLALPGETGTLITTATWQVNVPERPPFDIQHVIHWLLP
                     SPLTALMSDNTWLWPDSPGTPALTAGDWPVMETDTPTLKRVKRRTFTLIDNRNRQGWI
                     TRRFQCFPLAPLPESHSHRVPDILYPLKTEKKECKDNQQPHCLHS"
     gene            22944..24149
                     /gene="traW"
                     /locus_tag="ROH59_003406"
     CDS             22944..24149
                     /gene="traW"
                     /locus_tag="ROH59_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraW"
                     /protein_id="HDX4805849.1"
                     /translation="MQRQPATTLLALLIGCTVIPSTHAYPVTVVASQPVTTQIMPELA
                     TIQGIMEEMVRMQTATGTAITQNSEKLATVIAQDGQATRQQMIFSNETRRLEEARKSF
                     SVPDSICSESASGVAAESRRAAASAAARLSQGGGVSSKPIRERLSRAADSPTREAYDS
                     AGIHAGYCTEAEYARFGGTDVCPAVGELPGGDSQVRSLYQGAGTADTPAALTWDQKQI
                     DAATAYMKNTARPSAGRAPGKGEVGTQTGRTYVGLQNEYNGIIDAASHPQLSLIADST
                     PNEATRGALTEALQSPSAAAYFDRTASSEARTRGHMSQREFEAFEAGRRYANTDWQQD
                     LQGMEGDNLLRELLRTTALLNWQMNDLKEQIRQGNVIAGQQLALAARQYYGQRLGELS
                     QAMSQGSVR"
     gene            24146..24715
                     /gene="traX"
                     /locus_tag="ROH59_003407"
     CDS             24146..24715
                     /gene="traX"
                     /locus_tag="ROH59_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDX4805850.1"
                     /translation="MRDDNSTDKKKPAPRLRRIGDIGINLFAPLAETRWMLRSCRHML
                     GQHKTRLKRLMPDRQPESPVCMTWEEAVRASGLTVNELDRRLRRRRMFWRTGFWLMMI
                     PVLLLCGMALAATALPAITLIRILACLLLMSAIAALCASKALIASYRLWQLNERRVSE
                     DEQGTFPDYLQARHGWKQATWLAITHRQY"
     gene            24790..26955
                     /locus_tag="ROH59_003408"
     CDS             24790..26955
                     /locus_tag="ROH59_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotA/TraY family protein"
                     /protein_id="HDX4805851.1"
                     /translation="MKIIPRALSAGLALAAVPAQAFVTYQDIVSAATNPDDLSRQALV
                     TIFGDVVTNPLTASSNTIIGNLFMVFNAIIATMGIVWFLFIGIRHAVRTGHQGSVFNN
                     GRDVVGILSVVSGFLMIVPTASGWSLAQLVMLWGASIMGIGSANIMVQTAAENIAEGY
                     SMTVQPVHVSTRTAARGILEMELCKHAMNTGLDDFNRTARSSTPLMSESSRTENGRYT
                     VTVSNGSATCGSVSLSVKGNGSNKQSALAHFFNPFIETEYQGVLTAQRSAMDTMLRDL
                     DSAAQEFVSAYRTRRDTGNGNLPDIESRIQKAANRYEETVQKALPADNAETERREQLK
                     SYLTTYGWVALGAWYQTFATANQRLEDLANRAPTVSGVSSLGEAGDTEFLKEVKGAYQ
                     AQLLNSPYTPALGNLTSSDEIYAANTNDPQSAIIKLMSPDFTKLTYKIATVYSGTGTT
                     SYQANPLLKMKDIGDYTMVTTETIWAGYTTVRVLSSAGSNSVFGRLVNAVSGLSDAAK
                     AFLEAAAPPLYFLLFLLFCAGFSLSIYLPFIPFIFWMTGIGNWIISVLIGCTAGPLWA
                     ATHLGTSQDRGSRAAYGYIYLIDSMIRPLLMVFGFFFASVAIVAGGTILNALFAAALM
                     NVQINSVTGVFSMAGFLMIYARACTTLVAAIFALQAYLPDHVINFLGGRDGVNMLGNM
                     VSSVKDIIAGGNTNMRRTPGVREDRLKDIKGDDKDGIKQ"
     gene            27046..27690
                     /gene="excA"
                     /locus_tag="ROH59_003409"
     CDS             27046..27690
                     /gene="excA"
                     /locus_tag="ROH59_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid IncI1-type surface exclusion protein
                     ExcA"
                     /protein_id="HDX4805852.1"
                     /translation="MSTTKSRYPSWWAYYYLTRNAYFLIGVPFLIFCAIAFTALSLDI
                     YSTKYDYIYAYGSWALLIIPSLWLYLRTRAKKKKVQQVVQQIKESSPFAPTSDYEQLS
                     FSKSCYFGIDIKNGTMLYVRIYPNNVMDVIGLDIHNFTRTVAEDGKLEIHTTYVSLPM
                     IPLEISGISARTLANTMHTMAARGYEYKERFPQMIRYRVKEWEKVAGVPVAEVF"
     gene            complement(28003..28155)
                     /locus_tag="ROH59_003410"
     CDS             complement(28003..28155)
                     /locus_tag="ROH59_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001618166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HDX4805853.1"
                     /translation="MPQRTFLIMLIVVCVTILCFVWMVRDSLCGFRVEQGNTVLVATL
                     AYEVKR"
     gene            28488..28730
                     /locus_tag="ROH59_003411"
     CDS             28488..28730
                     /locus_tag="ROH59_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001317518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805854.1"
                     /translation="MSNEYQSTSINPDVFEQFFTLLNTHCKSSEAALAMLSTLCYELM
                     RRSGIHSLDSLMLNGEGILIQLQGADIREKTGQHIH"
     gene            complement(28823..>29365)
                     /locus_tag="ROH59_003412"
     CDS             complement(28823..>29365)
                     /locus_tag="ROH59_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HDX4805855.1"
                     /translation="VNSSSPKVIFIHMLGSHPNPCDRLFNDAQPFRELFGNKVSCYLS
                     TLLKLDRFLQAIYNMTTEHGDDFAMLYFSDHGQSVSSDSTPVHHAPGLRSGYDVPLMM
                     MASDITEHHLNHVHISARRFPEIFQWITGIQTKNLPLSFSLLQNDFAESVFVFNGERD
                     VPVLSLPEEPILTGNAESEK"
BASE COUNT         7313 a         8380 c         7451 g         6221 t
ORIGIN      
        1 tttctgtatc cagcctccta ccttccccgt ttttatcgtg gaaggcagat atgtttcaaa
       61 aaaacaaaac tcgcaaaatg tccctcagcc gggcactgga caaatacctg aagactgttt
      121 ccgtccataa aaaaggtcat ctgcaggagt tttatcgcgt caatgtgatt aaacgtcacc
      181 ctatggccga tcgctatatg gatgaaatca ctaccattga tatcgccggt taccgggatc
      241 agcgtttagc tcaaattaac ccacgaacag ggcgtcaaat caccggaaat accgtccgtc
      301 ttgaacttgc ccttttatca tcattattca atatcgcccg tgtggaatgg ggaacatgcc
      361 gtatgaatcc tgttgaactg gtccgaaaac cgaaaatcag taatggccgc gaccgccgac
      421 tgacttctgg tgaagaacgc cgcatttccc gctatttcag agataaaaat cagcagctct
      481 acgttatctt tcatctggcc ctggaaacag caatgcgaca gggggaaatc ctcacattac
      541 gctgggaaca cctcgatttg cagcacggag tggcgcatct tcctgaaacg aaaaatggtt
      601 taccacgcga tgttccactc tcccggaaag ctcgcaacta cctgcaaatt ctgccacaac
      661 agataaacgg caatgtgttc agttacacct catccggttt caaaagcgcc tggcgtaccg
      721 cacttctgga cctgaaaata gaaaatctgc attttcacga tctccgtcat gaagccatca
      781 gccgattttt cgaacttggt acattgaatg tcattgaagt tgccgctatt tcaggccacc
      841 gctccctgaa catgttaaaa cggtacacgc atctccgggc atatcagctg gtcagcaaac
      901 tcgatgccag gcgtaaacag accagcaaaa tttcccctta ttttgttccc taccctgcaa
      961 ctgtcgggta cagaaacggg ctgtttgtcg tgacactgca cgatttcgac cttgaaaccc
     1021 gtgcagaaac ccgggaactg gctatatctc atgccagcgt attgttgctg cgcacactgg
     1081 cacaggcggc tcagcggggt gaacgcgttc ccacgccagg cgagctaccc gcaaacattg
     1141 atgaacgggt catgatttgt ccgttaacaa actgaaggca tatcagaatg aaaataaact
     1201 ataaattccg gattaactta atcacagtcc ttctgtctca gctcctgata cagatatata
     1261 tgtggcataa cattccggta tccgaacata tccctccacc cattatattc cttatatcca
     1321 tatttttatc aggtctggcc atctgtactg cattctggct ggcatatgac agtgacagat
     1381 ttaagcaact ctcactgcca aagcaaatta ttctgttagt actatatact ggcggattca
     1441 attttttaat attatacgac ttcatgtaat acgcaacagt tctggaaaca accttatgac
     1501 attataaaca agggtacctt caatgctaat cccccacaac aaaacaaacg gccactttat
     1561 tcttttgctt tctgttaact catttatata aacttgtata atcgcaataa accagaagaa
     1621 gacaaaaaca aatgaaagac ataatgcacc tgtaaataac atacttataa aggtccattc
     1681 ctgccgacac aggacaataa tcattgatac cagcaccaca atagctgcat tacctaacag
     1741 agtttcacga ataatattcc ttataatttc cagtttttcc ttatgctgtt ttattttcat
     1801 acgaacctca tagatttcat cccgaaaagg aaacgatgat acaacagaat actttcacag
     1861 ccactctgcg gcataatgcc agaccagcgg catgctcagt cacttcctgt ccgaatcctt
     1921 ttcattcgcc cttaaaacag agttgcaaac actcttgaaa cacactcgat cataacgatc
     1981 gaaataactc gcttccgttt aaaaaacact ctctttagac tcaatttatg aacaaaacac
     2041 gctgacccgc atggaggtga aatgaaaact gacagcacag gtattgccgc ccgtatgatg
     2101 ctctccctgg acagggagcg aatttgcgaa tgcctgctca gtcatcgcca gctgcagtcc
     2161 acacccctgc aggttcgtta tccgcaggga gtcagggatg cccttggtat catgagcgaa
     2221 cagctttctc tttccgtctc tgacctgacg cgtatcctgg tcgaagacgc gttaagtgaa
     2281 atgtttcttc ctgcagataa catcgtccgc cgtcttctca gcaggatgga gcacatcatg
     2341 caggcacatg atatcagcgc aacaacgatg gctgcattac tggccccctg gaatatccgc
     2401 cctgccgtct tccgggagcc ggacagactc actgactatc tgaccgggga gattcttgca
     2461 gcactggctg actggtttta tctcagtccg gaatggctga acggcagggt gcattatcca
     2521 ctgtatcgtc cgggagactg gccagccaca caggagatat tctgcaggat tatttcagcc
     2581 cgcgagaata tggacattat tctctggcat ggttttccgt ttgccggaac gcattccgga
     2641 gaatattgcg gcgttctgct caggcagaaa aaagaaatta ataacaccat tatttatccg
     2701 gtactttcgt tatatccggt cagaatggat atagaaaaag aaggctggtt tcagatggcc
     2761 cgaaaaatat ctccggatat ccctgttcgc gccgtaacac tcactccggc acaggcagaa
     2821 tatctgataa caggaaaaat attacccact gcgttattca gggtcccgtt atccccctgg
     2881 taataatact gagcaataaa ccggaataat acaccaactg tttttaatgg cacagccgtg
     2941 ccctctgttg ttatacccaa aatacctcaa tacaggaaac tgaaatgatg atgaaaaagc
     3001 atattacccg tactctcatc gcgtctgccg ttttattttc ctttaattcg actgcagcaa
     3061 cgtcatattt tgaagcccgc aatgatgcga tgggaggaac gggggttgcc tcctctcact
     3121 atggtgtggc cccactggca aacccggcac tgctgacaaa atccggtgca aaagatgact
     3181 tcagtcttct gcttccgtcc gtgggtgcgc agctgtccga tccgggtaat atcgccgaca
     3241 acgccgacaa aatcagcgat gactggaaag ccttcgaccg tgccgtcgac agccactccg
     3301 gggtaccgca gacagcggcc cgcctgaaag agagactgca ggacttccgg aacacccatg
     3361 ccagcgcaca ggccggggta tctgctgtgg cggcccttcc cggtgatacc ctcgctgctg
     3421 cactgatgct gaaaacgctc gggactgtca gcgtcgacgg taaagtcagc gatgccgacc
     3481 tgaactatct ggaaagcatt gcagacagtg gcagccagga tgtggataaa aacagactga
     3541 cctcacaggc ttttgcccgt gccgcactga tcaccgatgt gggcgttgcg ctggccactg
     3601 aactggaaac ggccggacaa aaatggtcac tgggcttcac accaaaattc cagcgtgttg
     3661 acctgtttaa ctacaatacg ctgatcaaaa actatgacag cagcgcattc aaaggtgacc
     3721 gttaccacaa cacccaaaac ggtattaacg ctgatatcgg tgccagcatg gacctggatg
     3781 acaactggac gctgggtctg gtcgcacaga acctgatccc acgcagcatt gagaccaaag
     3841 aggtacatgg tgtcactgaa accttcagga tccgtccgca ggtaacgacc ggcgtatcat
     3901 ggcacaacga catgttcacc acggcactgg atgtggatct gaccccggct agcggcttca
     3961 catcagacag caaacgtcag tttgccgccg ttggtgctga gtttaatgcc tggaaatggg
     4021 cacagttacg taccggttac cgccagaatc tggccagcaa caacggcagt gcattcactg
     4081 ccgggattgg gctctcaccg tttgatgtga ttcacattga tgtcgccggc ctcgtgggca
     4141 ccgacaacaa ctacggtgcc attgctcagt tacagttcac cttctgatta tcacgccccg
     4201 ggacgcccgg ggcttctgac ctgaatctgc tcgtttccgc tcttctggcc actcaccgcc
     4261 agtcctgttc attattttcc ggataaaacc atgcaaaaaa aacgtatcac ccttgcaggg
     4321 ggagttgcca tgctctgtct gagcggctgt catcttcccc cggataatac cgcaccggcc
     4381 aggaagtacg gtgcagcttc tgaagtcgct gtcacacgac atgcacagta tcagttgtgg
     4441 gagcaggaca cgtattctgc agccctgcct tcccgccagc ccggaggcag cctgcaggct
     4501 cacagcgggc gggtttcctt tgactgggaa ggcgatgctc tggagctcct gagcgagctg
     4561 gcccgtctgc gcggacaaca gttcagttac agcggcgtgc gtcttcccct gcccgtctca
     4621 ctccatgtac gcgatatgac cttcgctgat gcccttcgtc tcacagaggc ccagactgcc
     4681 tggcgggcag tcctctcaca gtcagccggg cgtttacatc tttcctatat gccaacggag
     4741 aaaaaatgaa aaaacaggtc tgtctcctgc tgtccgggct cctgctggca ggctgtgccg
     4801 gacagcacca tcgcccccct gccggtatgg caggcaattt accaccgccg gatctccggg
     4861 catggctgac gcccactgac aaccaggatg acggcatttc agacacccgt cgccagatgc
     4921 tcacggacgc cggacgaacg ctgggattcc gtggcggaaa agcacagcgc tcatgggaac
     4981 tgattcaggc actgaatgcc cgggaaagta cactgaatgc cctgtatgac ttccgtcccc
     5041 ttatcagcag ggaaggctgg ctaccccctg ttattgatga agcgcaggat gttgctcaca
     5101 ttcagcctga ccagataaga acagcgtccc gtgtctggac catcctgcgc cccgaacgtt
     5161 ttgtcagtaa cccgccgggc tggcgtgact ggcttctgcg ggggctttcc actaccgcta
     5221 ccccgggaac tgagggccgt gttgtaccgg aagaccgcgc acagcgcaga ctctgggaaa
     5281 acgcactccg ccagggctgg caggaaggcc gtgacaacgc tgacctcacc ctggaagcca
     5341 accagaaacg cctgacccgg gattaccggg gaatgatgct ttatgccctg ctctggcgtc
     5401 agggcatgat cacacgcccg gatgtgactg aacagcggca gaccgtcacc ggtaacggca
     5461 ggaaactcat caccggagac cacgtccgcc gtctgaagac acacgcggaa ttcaccctgc
     5521 agaaatcacg ctggcgtccg gtcgtcagca cggaaggagc ccccgatgaa attacccgat
     5581 gagttcggca cattcccttt cgcccgtttc acggccgaag agtttcgcta tttttttgcc
     5641 tggtgtgccc gacactgcgt cagtgatatc gatctgacag gcggctcacc ggtatctgtc
     5701 agccgctttg gacggcgggt acgttcgtcc gcacatcctc tgccgtcctc catcatgatg
     5761 gcgctgagtg atgaattgtt tggacgggaa gtccttcccc gggtgctgtc cggtcatccc
     5821 gtggaccgta ccattcaggt cagcggtgat gcctccggtc gctacggtct gcaacggggg
     5881 cagcgtgttc gcctgcgctg tcacctgatt cagggaacat cagcaacaga agaaaaagta
     5941 atctccgtca ccatgcgggt gatcccgtcc gatattccgg acatcctcac catgaatatt
     6001 gaaccggacc tgctggatgc catgctccgg aaaaccggtc tgggtttcat ctgcggagag
     6061 accggctccg gtaaatccac actggcagcg gcactgtacc gctacattca gacgcatttc
     6121 cccgaccgca aaacggtgac ctatgaagat ccggtggaat acattctggg gggagagaat
     6181 gaccttctgc caccccatca ggccgaaatc gggcgtgatg tggaaagttt tgcggcagga
     6241 cttcgctctg ccgttcgccg taacccggac atcatcggta tcggtgaaat cagggattat
     6301 gaaacggcag atgcagccgt ccaggcaggt aacaccggtc acttctgcat cggcaccatg
     6361 cacaccaaat cacccggtga aacctttgcc cggctgctgg ggttatttcc accggaaatc
     6421 agggattcaa tggcagccgc caccctttcc ctggtgcagt tcattctggt gcaggtcctg
     6481 gtcagaacaa atgacggtgg cagacaggcc gtccgggaat acatcgtcat aactgacgaa
     6541 ctgcgtgata cgctctcccg gcagtcccat gcgacatggg ggcattacat tgatgaaatc
     6601 attcgcaagg aaaaacggcg gatacgggat caggttctga ccatgtatca gacgggcagc
     6661 attgaggcat cagaagctgc gctcttcatc ccggccggag aattccccaa atgaaacgcg
     6721 aaggcttctg gcgggatgtc actccgccac tgaatattta tggtgtcccg ttgccgttta
     6781 ccatgattta cctgctgctg tttccgtatc cgtcaaaaac aacattctgg gtgtgcagcg
     6841 gcattctgct gttttttgtg ctcctggggt actcaggatg gactgtccgg acgctctgcc
     6901 ggcgtctgta cagcctggtg cagggtaaac aggcgtcagg ccgtccctgg tggtaccggc
     6961 atcgcacaga attaccccgt gaatggcgcg gaacggaata accctctttt ggttaccatc
     7021 ccggcagaag aactgagggt gaaaaagaca ggcgtatatt aatgactatg agtcttaacg
     7081 ctgagatccg tgataatctt cgcttcggtc cggagtctta aaaccggcat ctggtaagaa
     7141 caacgtgggt aacacggtga atgccagcgt ccgttactcc ttctgataaa aaacaagggg
     7201 ccgcccgccg gccctgatat tgcggagaca atatgtttta ccctgctgtt gactatcttg
     7261 tgattattct gcttcttgcc tttctcatgg tgactttatt tgcctgtatc ttctgtctca
     7321 gacacgaata tataagaaaa gaatcagaaa aacgaaaaaa ggactttttc aagaaaaaag
     7381 aattgaatat cactgagttt tcatggttca ggtacaacca gcataatgag accggaatta
     7441 atattaccat ggataaaacc atcatcgtga tggtggctgt gaacggccgt atgttcagta
     7501 aaaaatacag tataacctca cttacatttg acacaaaaaa tattaccgaa gcggcactat
     7561 atgaaaacgg cattgtcacc cgtaagctca cgcttcatcg acatgtcagt gatgacaggc
     7621 ctgcaggcgt tccatcgaaa cagcccataa gaacaatccg cctctgtatc agacaaaaag
     7681 atcacaccga cgatatttct ttcatcctct accagggacg tcttgaacaa cgaggacata
     7741 actacaccat aataaaaggc aaggctaatt ctgttatcct gttattaaaa atgctgctga
     7801 caaacaaaat ataaacccgc tgctcctgtt gttattcaga cgggggcaga ataaagataa
     7861 tatttcataa ttttacccaa aatactgata ttcatacctg cttgttattc tcacattaat
     7921 ctatcttcgt tctgttaact actgctgaac gcaagccgtt ctccttaccg gaatacgggc
     7981 aattctgttc agccatccgg agccagcaca atgaaatcac cttacattac ccggcatgcc
     8041 gtcccacatg acgcgcaacc tgaaccacac cgcattaccc cgtgaatggc acggaccagc
     8101 atcaccctct tttgttcatc atcccggcgt atcacaacgc cctcatcttt aatccccgga
     8161 gaacgacatg aagtccagat atcgaacctg gcttgctgtc ccgcctgagg agacagaagc
     8221 cgtaaaaaat gcagttcccc cgttaaatgg ccgcaaagct gtcgcatggg atccagaaaa
     8281 aaagctctgg tatgcccggg cgggtaccga actttcactg ctggagcgct ggttaccccg
     8341 gccacaggaa ctatcgatgg atgccggcga tccggtcact gaatttgctc aggtcctgga
     8401 aaacgccggg ctggttattc agggattgcc acagatggac ggagccatac acagagtggc
     8461 cacccgggat gacaaaaaag gggccaaaag tggcgcatac agggcctatc ttgatggtcg
     8521 tcccgccggc tggtaccgcg actaccggag cgccgatgac agtcccacaa actgggtatt
     8581 ttccggcgga gaacaacacg atcctctggc cagactgcat ctgcgggcat tcgctcagca
     8641 acagcgcgat gataacgcac gtaaactgca gcaacagtat aacaaacagg ccggctatgc
     8701 ccgctcctat attaacgggt tgccacaggc aacagcacat gaatacctga cgcgcaaggg
     8761 catccgggcc gcgcctggcg tgcggctgaa caataaaaat gagctggtta ttcccttcag
     8821 caacggccgg ggagaaatac gttcgtacca gcgtattccg gtcaccggcg ggaaggatgc
     8881 ccgcattctg aaagactccg agaaaaccgg caactggttc accttcggaa ccccggaaaa
     8941 tggccgtccc ctgttatttg cggaaggtta cgctactgcc gcctccctgc acgaagcaac
     9001 cggccttccg gttctgatga cagttgatgc cagcaatatg attgccgtgg cagaaaatgc
     9061 ccgccaaatc tggactgaca gcccctttgt cttctgtgcc gacaacgatc atcaacggga
     9121 aattaacaaa ggggttttta gtgcaacaaa ggccgcagaa gtcacgaatg gcgaagtcat
     9181 tattccggcc tttacggagg cggaaaaagc acagggactg accgatttca atgacctgga
     9241 cgccagccgg ggacgggacg actttcagaa tgccatgaac gcacagttaa aacatatcgg
     9301 tatccccaca cccaacagtg acactgccga caatcgtgag gctgtcgtga tcggcaacct
     9361 gatattcaca ccggtaaaag atgagaagcc acaaatgtcc cctgaaaaca gacagagcac
     9421 agccccggaa acggagctgg cgacacagga tacgccttat gacacccact ccgacgatac
     9481 agaaaaccag gcatatgaag atgactatgc cgcctatgca tccctgcaat cagtaactgc
     9541 ggagacgtta tccccggata aaccactgga gaatattgcg tctgccgctg ataccggcac
     9601 agagaatacc tctgcggcta ccgctggcga ccaggaagac ctcaatacag acgccacagg
     9661 tacagacacc gctcacaaca gcgacacagc agaaacagga acgcttcctg aacctgccgg
     9721 gatgcagtcc atgcagcagg caaccactga accgaccgca gaagataaac cacacgagaa
     9781 cgttgtttcc gctgccgata ccagagaaga aaatgcctct gtggctaccg ctgataccgg
     9841 tgaagaaaat gcctctgcca ccaccgctga caaccagagc acgcaggcag aagaacatcc
     9901 ccggagtgaa gacacaccgg aaacctccct ctccgacgcg gccgggacac agcacaccac
     9961 cacaacgcag tctgaagaac aagtgcaggt ttccatggcc agcgctgacg actggagcgc
    10021 atttgcggaa gatctcaacg ctgacactcc gggggccccc actgttcaca acaccgacaa
    10081 cgcggagaca aacacagttt ctgaaccggc cgggatgcgg ccagttcagc aggtgaccac
    10141 tgaactgacg gcagaagata aagcacagga aaagagcgtt gcgtctgccg ctgagaccgg
    10201 cgcagagcac tcctctgaca tcaccgatga caacaggaac gcacccgctg aggagctcaa
    10261 tgccgatgcc acggttgctg ttcacaacac cggcacagca gaaacagcct caccttctga
    10321 acctgcagaa actcagccag tccggcaggc caccgctgaa ccgacggctg aagataaact
    10381 gcaggaagag cgtcttgtgt ccgccactga gaccagcaca gcgaatgaag cagcccgccc
    10441 tgaaacgcca tcgcttttca gccgtctgcg ccgttttctg accggtgtga aatcacgcac
    10501 ctcagaacct tccgttattc aggagaaaaa gcccacggag gctgaaacag caacagagga
    10561 ggtcgcacca ccatcaccac cggaaaccag cccggaagac acatcgtcag cggaaccgga
    10621 cacgattatc tttgcacccc gccgtcccga cagtccgcag cggcacaacc tggacgagat
    10681 ccttaaaaat cttacacaca aagagtttcc cgacaggact gcgctctaca gcgttgacgg
    10741 tgaacccgcc ttcctggaca gactctactg tctcgaaatg gtggatggcg ccagcgcgga
    10801 tgacaaaaag gtcctggctg cccttgctgt ggccaccaac ttctatggcg gcgttatcga
    10861 gctgaccggc agtgatgcct ttaagcaaaa agccatgcag ctgattgtcg aatacgacat
    10921 caaggttcgc atgaaactcc cggcccagcg ggcagcactg gaaaaactcc gcaaggaaaa
    10981 agagatggcg catgatgcca ttgtcaccca cagacccacg ccggaactca accgccagtc
    11041 accggaagag acaacaatgg cccaaccggc tccccctgtg tcaccgaagg cagaggctga
    11101 acaaacagca ggcagtacgg ctgaaacacc gcatccggaa gcgccggtca cggcaaaagc
    11161 tgaagccccc cgggccgaca gaccggaaca ccccgccgcc ccgtcgtctg cgccagaaaa
    11221 agcccctgtc agtgcacagc cgcagcaacc cgacacaccg gaggaagagc cgcccggcaa
    11281 gctcagcccc ggtgaaagtg tgactgccgt cctgacaaac tacggagaaa aagagtatgc
    11341 gcccggaaaa gggcgctgct tttttgtgga gctcaccaac cgcagtggca aacgggaata
    11401 ctggggaaac ggcctggaag aactggtcaa aaaccatcag aagggtgacc ccgtcacact
    11461 gacactgcag gcgagagaaa cattccggct gtccggtgaa acgcgggatc gtatccgtaa
    11521 tatctgggcc ataaccccgg tcagtaacgg cattaccgtt aataatgacc aacctcatgc
    11581 gggtcagcat accctggagt ttccgatggc aacattcagc caggtgatgt tacagatgca
    11641 acaacactgg ccacagataa tgcaggaagt tcgctccccc aaaaatcctc ccaataatct
    11701 gtacattggt gaagacaggc aacctgcatc agcacctcag gatcaatcaa tgcgactccc
    11761 cctcgctggt aatgcaccca atgaactgat accagccatc gcctctgccg ataaggacaa
    11821 tcgtcagttg aatcttctgc tggtccacag cgcagatgat catctgcagg gcgtggtccg
    11881 cctgaacggc accctttacc cggcactggc caccccgtca gctgacaacc gtcagctggt
    11941 catcaatgcc ctgacggata acggtctgca gtttgccggt tacggtgaag ctgttaacca
    12001 tgatgagaat aatcatcagc gtccgtcccc acaaataatg cagtttcacc tgaagcaaca
    12061 ggactccccg ttgtttgccg ccatccacaa accggaagag caaccggaca agcttttccg
    12121 ctctctgggt tttgagcaga cctggaaaga gtggtctgac agccaaaagg cggaggacag
    12181 gcaggaaaaa actctgcaac aggcacaatc ccacagcccc ggccgatgag ccggtaagga
    12241 cgaccatgaa catgaaaaaa acgctgctgg tcatactgac cggcatcacc ctggcatcac
    12301 cggtggcagg tgccgccacc tgccgggcgg gggccgctgc cgaagccggc agcagagccg
    12361 cctgggagcg ggcgcgcaca gccagccagg catggtcaca gcgggagaat gacgtcgcct
    12421 cctccctgca gtcctgcctg tcccgcatca aggacatcag tatcactctt ccgcagttcc
    12481 ccagcctgga caagctcctc cgcgacctgg aaaaccaggt ctgtgatgcc gtcgtggatc
    12541 gggtgaatga ccatcttccg gggaatatcg acccctggaa agactacaac ctctgaacag
    12601 gagcaccatg agcgaagcac aacccacctc ccctgtctca ccggaagcgg ataacagcgg
    12661 agatatttat aaccccgtgc tcagaaccat cgcacagtca gaacaacggg ccgcgctggt
    12721 acccggtctg gtcagggcgt tgctgtgcag cggcgcagca ctctgcatca gcctggtggc
    12781 taatggcata cagtactggc atgccaccgg cgtgacgcgc gaatactttg ccactgacaa
    12841 tggccgactg gtccgtctgg caccaaccag ccagccggcc tggagtcaga gcgacgtcat
    12901 gaactttggc agcatgacgc tgagcgaagc cttcaatctc gattttgtcc actaccgaaa
    12961 acaaatcacg acacaggccc cccgcttttc cgaagccggc tttgccggct atgtgaatgc
    13021 ccttcaggcc tcgaacattc tcgacactat taaaaaggag aaatttaacc tcacaaccac
    13081 tatcggggca ggtaccctgg tcaaccaggg acagatggag aacggtgtct ggttctggaa
    13141 attccagtat ccggtcagga tgcgcctggt cggtcagacc agcacccgcc ccgaacaggc
    13201 cttcaccttt gaaatcactg tccggcgcgt tgacccccgc atcaaacccg gcggcatgga
    13261 aatcagccag atggtttccc gtaacgccgc agcaggaatc tgagactcat atcatgcaca
    13321 tacatcatct tattggcgca ctgcttattg tgtgcggcac tgtcacagct gcagataacc
    13381 cgggctggaa aaatgcacga agcccgcaga ccggcggaaa gaccgcacag gcaaccggga
    13441 acaccccggc aggcggtccc ccgccagccg cacaactccc gggaaacctg ccgcctcccg
    13501 gcgctgctct tgtacaggaa ggcgcatcgc tggattcgcc cctgaatgcc ggtgaaattc
    13561 gtgaactccg tgggataatg gccgataacg aacgggccat cagtgccccg ctcaccagtg
    13621 tggtgccccg tatcagttcc ctcacggtga atctgtctcc gggggccagc ctgccccttg
    13681 tccgtaccgc tctgcataac gtcagcgtgg tgaccttcac ggacgtcaac ggcagtccgt
    13741 ggccacagtc ggatccgccc tataacgctg cgcccggtca ctttgacgtg cagttcaacg
    13801 gcaatatggt gtccgtcacc cccctgcgcg cctgggctgc cgggaatgtg acggtctatc
    13861 tcaaaggatt gtctgtaccg gtcatcctga atatcaccag tggtgaaaca gacaccacta
    13921 ccctgagtca ggaaatcgac agtcgtctgg atctgcgcat tccccggcag ggacctgcca
    13981 gcccggtggt gtccataccg tcagaaaaaa ttgccctgca tgacgccacc ctgcaggcct
    14041 ttctggacgg tgtgccaccg gatgatcccg ccatccgccg cctgaaattc tccggtaacg
    14101 tcccggacac caccatctgg cagcacggcg atgatcttct cgtgcgctca cgggccatgc
    14161 tgcgggatga atttgaacag acgctggcat cggctgatgg tacgcggctg tggaaactgc
    14221 cggtgacccc cttactcacc ttctccgtga atggtcagtc cgttcacgtc accccggaac
    14281 tggagtaaat catgagcgca gaacaagaac aggacacagc cgaaaaatcc ggcaaaaagc
    14341 tgtcagccct gctggttatg gggggcgtga ttatcatcgg gggcggatac ctgctgctca
    14401 cctggctgtc ccccgaaaac gctgcatcgc tctcgtcagt caatatcaac agcacaacgt
    14461 ccggcggcgg acggaacgtg atggagacac agcactaccg ggatttactg cgggctgaca
    14521 atgaacgtgg tgctgcagaa gcgttacgta ataacgagac gtttatcgcc agtctgcccc
    14581 ggggactgga taccgatacc ggaaacgatc agaaaaggga taatcccccc gatgatcagt
    14641 caggcacttc cgggcaaaac gcatcccccc ctcaggaaga tcagactgcc cgggaaaaac
    14701 agcgggaagc gttacaaaaa ctgcttgccc gcatcaacac acagcatcct gacgcccgcc
    14761 ccccggtagt ggcggctgca atgtggggca ccactggtgc tcccgggata agctcacatg
    14821 cctcaccacc cggtaccggc acatcaccac aaccacgtct gcaggaggcc agtctggcaa
    14881 ccccggcagc tcgtacaggg atacagctga taccggcact gacccgcgta cctgccttca
    14941 ttgatacgga agtggactct gacaatgctg tctcccgcgt ggtggcctcc gtacctgccg
    15001 gcccatgggc cggggccgtc ctctacagcc aggacgccag actcgccggc aagggaatgg
    15061 atatccactt tgaccggatg atgtggcggg gcatgtttct gaaagtcaat gcatatgccc
    15121 tgaatgaaca taccggcatg tcatccgtgg ccagcgacgt gaaccaccgc tggtttaagc
    15181 atatcgttct gccgtctgtg ctcggtgggg cgggcagtgt cgggagtctt tacaaagacg
    15241 ccaacacaca ggtcattcag ggaaactacg gcagcattac cggcagggtg ggaatgcctg
    15301 atggcagggc gctggccggc gtcattgcag gcggcatggc cgaacggggc agtcagttgc
    15361 tgacccgcca ggcggagagc gaaccttacc ggcaggtgac agtgtcacgc ggagaggttg
    15421 tctccattct gtttgttgag ccggtcatga gcaacgatat cagtcccccc tcctccggca
    15481 ctgccccttc tgtgccaccg ccctccggac gcccgctcac ccaggaagaa gcagagcgtc
    15541 aggcgtctga caggatccag gcagctgtca tacgtaaaca gaacgaaatg cggcaacgtt
    15601 acggaataca acaggaaagt catccatgaa aaacgaacat gaagatcccg gcagttttgg
    15661 cgaaacaacg acaccggcat ccggcaaatc cttcctgaaa cgccagtata tgggatacag
    15721 cctgccagtc tgggccggct gtgtcctcat catcctggcc gcagtctggt acaagtttct
    15781 gcggacaccc tcagagcccc ctgcagatgc aggctttgct gtcacaccgc ccgctgctga
    15841 gagctgggca gagcccatga ccatgacgga gaccgggggc ggaaacaaca tgcccgcacc
    15901 gccggttgcc ccacaggcag atatgcagca acttgcccgt gatctgaaag cagagctgga
    15961 cagacgggat gaggaaatcc gacgcaccct gaccatgctg aaggacagta tcaccactct
    16021 cagtaacgcc attcagaagg atgaggcctg ggcacaggaa acccgtcagt tgcttgagga
    16081 gacccgtaag caggtgcata ccctgcagat gcagggagca ctgccagccc cgaccgggaa
    16141 taacagacag cctgcgaaaa ccctgccttc acctctgcag ggcatgaaaa tcatgtcggt
    16201 ggagaaaggc atggcctgga tccgctggca gggcagtgcc tgggcagtac gggaaggcga
    16261 cagtctggga aacatcacca tcacccggat tgacccgtcc agccgggcag tcatcacctc
    16321 tgccggtaca ttacgatgat gagcattgat gccctgacag ccatagagaa ctttgccagc
    16381 ggtattttca gtgcaggcat ggagtttctc tttacctggg gagagctgct ggggattatc
    16441 ggccttatcg gtcatctgat gcgcgcccgg gcagaaggac gtcgcagtat gggaccggga
    16501 aaatttattg ccggtatctt catctgcggc atgctggtca gtctgccctc aatgatcaat
    16561 gccggaggta cccagatggg cttcagggca gattctttcg cccccatcgc atacgtgcag
    16621 ccgggctcct ttggtgccgc tgccggtgcc gtcaatgcca ttctctcact ggcaaaactg
    16681 gccggcgtcg gttttgtcat gaacggcata tccatctggc gcaaatcact gctggacggg
    16741 cacaccgccc tgagcgccag tgaatccatc agtaaaggga acgtcaagtt tgtggccggc
    16801 gttctgctgg ttttcaacga ccgggttatc gatgccactc tggcaagcct cggtatcgcc
    16861 ttctgacccc tgtatttttt cagtaaatca atctgttaat aaaggagaca ctatgtcacg
    16921 acttcgtgcc atggcggcgc gtctgcgcgc tgcatctgtt tatgttcagt tatgcctgat
    16981 ggcctgccgt gaccggctgg tacgcctgtt actgctgctt cccgtgatgc tgctgcccca
    17041 caccgcaatg gcaaataccc tcttcgatat gattaaaacc gttggcgatg gtgccagagg
    17101 ctccagcagt tcgtttgtgg ctatcggtca ggttattggc ctggtgctct ttatcggcgg
    17161 cctgcttggc ctcaaacaaa tcggtaaaaa acccggtgca gggctggcct gcctgctgtc
    17221 aattctggtc ggcgtctgcc ttgccgtcgt accggaactg atgggcagcg gacagaaaac
    17281 gctcggtctt tctccggttt caatcagtta atccgcaaag gcaccgggaa accggtgccg
    17341 tcttcacaca atgaggagga ccagaccatg tcctgtgagc tgcccccttt caccctgctc
    17401 agaacagagc acggcaacgt gattgcccgc gacaaccggg ataatcagga gtttgtgttt
    17461 gcagagtgtt actccaccgc tatagcagca ctgattctgg ctgccgtcac cctgtataca
    17521 gagagaaaag cgtatgaaaa agaccccgcc actcatcgcc ccggtccggg aacgatggct
    17581 tttcccgctc ccgcaaccgg acacggtatt cagcggtgaa gccctgttac caccgtcagt
    17641 gctctcaaca gagggacgct gcccctgctg tcgcaggacc gtcacccacc gcttcattct
    17701 ggaagattca tggccattac agcagatggc tgacacctgc cgggatacgg tcgtcctgct
    17761 ggaaaaaaac ctcacccggg tgatgcgcct gaaaaaacgt ccggtaccgg aaaacgctga
    17821 cgaaaaaaag aaacacaccc gaaccctgca ggatgcggag cggtccctgg cacaggcccg
    17881 cctgtcggcc aggcgactgg ccctgcgtca tgtggaaaag tcgcaaatcg tcacaacgga
    17941 tgcactcagc gaaaatgaaa gtgacctgct gcagccggaa ggcccgccct ttcatctctg
    18001 tgccttctgc catgcctggc actgtctgaa cggctatgct gccgcacagg gagtgatggt
    18061 ctggctcccc gatttgcatc cggcctcggt ggttgccctc aatgcgcggg cactgcagga
    18121 gattttcagc gataaccgtc agcgggtcag gcagggacgg gcagtcctga atgccctggt
    18181 acagaaccgt ctggccgttg aggagaaatt ccgcacctgg cgtccggcgg attttgctga
    18241 tgcactgcgc cgctggccgc cggcacagcg taaaacactg cgggagaaga tggacggggt
    18301 ggcgctcatt ctgatgccag attcgtttcc tgacaaaaag tacgtcatgt gacacacacc
    18361 gctgccggtg acgttctgcc ggccccaact gacagaggaa caaaaaatgg ataccctcac
    18421 tgccggatat cagttttccg cagattcatt ccggcgcttt attatccgga cgctgacgga
    18481 cgatattccg cctgacggag atgaaaaaga gattgcccgg ttcattctcc gccacccggc
    18541 atttaacggc ggctggctgc tctttctggc tgcagaaatt catgaaagat cccataccca
    18601 taaaagcatc accgtcacag tgagcgtcga taactatctc tcatggatgg atattgccgt
    18661 atccggtctc ccggaattac cagatatgcc cttctgtgat tttttcattc gccgccagca
    18721 gtttatctat ccgggtgtgc ccccgacaaa atcaggagaa gaatgatgaa aattcaccgc
    18781 atatccccgg agacgcttat aacactcatc cacgcacacc tggccggaaa aactgacagt
    18841 accgccaaag aagagcaccg gctactccgt cgtttcctgc gggatgatga cggcaggctg
    18901 gccggcgtac tgctgaatat tgccggaata cttcagttca acagggaatt aagtgcgcgg
    18961 cataattatc cggccacacc cctgactgaa ttttcattaa ggaaacgggg aaaacaactg
    19021 catctctgtc tctgcagtct ccgtttcttt tatatccccc ctgtatttat acgaaatgaa
    19081 agaagaaaat gtattgttgt acatattaat aaaatcactt atccgccagt aaattcacta
    19141 cgctgacagc gtgtttccac cttattacat ttttattatt tactgtaatc acacagaaat
    19201 acgcacctgc ctctcaacag attatttatt ttctctgctg ttttttcatg ccacatcccc
    19261 tgctgtggca tcaaaaaata taagaccgtg atgattcatc cttaccggag tgccccatgc
    19321 catgaatatc aaccgcatta tttttgccat tgaagactgt atcagtaccc tgtcacggta
    19381 ttccgtttcc gcattcttcc ccgattactg tgatctgcac accgtcatcg gtctggacca
    19441 gcaggaccgc gaacgccgcc cctggctgaa agccccctac attgccacca caaaacaggg
    19501 gtattacctt tccgtctttg aaatcagcgg tgccctgaaa gaaatggatg aaaacccgga
    19561 cctgacagcc cccggcacac tggaatcact gattacagcg ctggcagagc gaatgaacac
    19621 tgcctggaaa aattccggtc acaaaatcag ttttgttttc gaacgcgatc cggagcgtgg
    19681 aagggatgaa atcgaagcca tgctcttacc ccagcgaaaa tccatcgcac gcacggggat
    19741 cctgcttcag gacgttctgg atgaaaaagt caccacgctc accccctggc ttgtccggga
    19801 acgctgctgg ctgaccgtct ggagctctga agaactgctg agccggaccg atcgcaagga
    19861 ccaccagacc cgtatcagga aactcgctga acacgctccg ccagcccgat ttgcgcagga
    19921 tccatggcgc tggacacttt ccgcactcaa aatacggcat gacgccttac tggacacgct
    19981 ggagcaggcc ctgacacatg attctgatgg tctgctggtt cgcctgatgg atattcatga
    20041 agtgggacgg gaaatccgcc gtcaactgga gcgcaacagc acacctgcag tatggcagcc
    20101 tcatctgcct gaagatgccc gtcctgccgg ctggcgacag ggcgaggata cctctgtatt
    20161 ccacgcaccg tcgctgaatc tgcagttatt caccacacag cctgaaacac acggcagcct
    20221 gataaaggcc ggtgacctct ggcacggtat ggtcgccatt accctgccac cccagaatct
    20281 gcggacattc aaccagctgg tcagggatgt gccccgcgca atcccctggc gtatccggat
    20341 ggatctgatg cccggcggca tgaaggcgct tggggtcaag aaaaccctgc taacctacag
    20401 cagctttatt tcccctctcc ggcccatgta tgactcggtg atgatgctga atgacatcaa
    20461 caaacatgat ccggtctgta tcatgaccat tgttgccacc acatggggaa acagccggga
    20521 agtctgtacc cgcaaccagg ctctcctgaa atctgcgctg gaaggctggg gagtatgcgg
    20581 caccaccacc accttcggtg atccgagacg tgcctgggtg aacacggttc tggcggcctc
    20641 ccacggttcc ggtccagtcc ccctttaccc gcccctttca cacgcccttt ccctgtttcc
    20701 cctgaacagg gccggctctg tctggcgggg acagggaaat ctgatgatgc acaccgagga
    20761 cggctctgca tgggaggtcg cgctggcatc gtcacaacag aacaagcaca cggaactgac
    20821 gcccggcgca cccggtctgg gcaaatcggt actcatcaac gcactgtcgg agatccagat
    20881 agcctcagcc cagaagaacc tgcctttcat tgcctatatc gacaagggat tcagtgcaca
    20941 gggactggta cagcttatcc gtgacagcct gccggagcag agaaaggacg aagccgtggg
    21001 gatcattctg agcaatgatc cggaacacac ccgtaacctg tttgatgtga tgtacggtgc
    21061 cagaaaaccc gccaccccgg aaaagaactt catggtatct gtactctgcg cactgtgcgt
    21121 ggataccggc accggtcagc cctgtaatcc cggtgacacc cggcaaatca taagcaacct
    21181 ggtggatctg gccttcaggg agtatggcga aaacaacccc agactgtacc gtgcaggaac
    21241 agagcccctt gtggatctcg ccctggaaga gagtggcatc gcagaacaac atgacgcagg
    21301 atggtggaat gctgccacct ggtttgaaat cagggacatg ctgcatatgg ctggcaatat
    21361 ccccgcagcc cagcgggcac actaccaggc catgcccctg ctggctgaaa tgtccgccct
    21421 gctgggacag ccatccatcc gggatgtgtt cggcacagtt cagcgcgata actcagcaga
    21481 attgttactg gactacatcc gccgtgccct cgatcaggga cacagtgact acccgatgat
    21541 gtccggctgt acccggttta tgctcagccc cgacacccgc gttgtggccg ttgatctgaa
    21601 caatgtggcc ggtgacaaga cacctgccgg gcgtctgcgc accggcatca tgtacctgct
    21661 ggcaggacaa atcgccggcg gggattttgt cctgccgcag tatcaggagg aaatacggaa
    21721 aaatctcgac ccacgctacc atgaggtgat tttccgccgc attgaacagc ttgatcagga
    21781 ggtcaagacc aaagtctatg acgaactgca caatgcaaaa gggatcaact tcatctggga
    21841 agccctggac acccaggagc tggagcagcg taagttcggg atacgcacag tactgagcac
    21901 ccagctactg caggactatc caccggcagt tctcaaatcc gccaacaccc tctggttgct
    21961 gcgttaccgc cctgacgaaa ttccgtttct gcgggataat tttggtgtcc ctgaagtcac
    22021 cctgcggcgc ttcctgaaaa tgccggaagg ggctgcaccg gatggcagcg gtgtcccggt
    22081 actggctgtg ttccgtgtaa aaaacggtac gctggcccgg atcctgaaat tcactctcgg
    22141 tccactggag ctgtgggcac tgaattcctc acccaaagac agcgccctga gacgtgcgct
    22201 gacgcaggag ctcgggtcac tgcgggcacg ccagatcctg gcagaacact ttccccgtgg
    22261 ttcagccacc tcactgatag aacaccgcgc ccgtacacat gacagtgaaa acgtcatcca
    22321 tgatctggct gcagaactca tccgtaagca gggatatcac ctctgatgta cagcatacac
    22381 atcactcccc gctgccggcg tcctgcacgg ggacaggtct tcctgaaaac gctgcgcgtg
    22441 gacggtgaca gtttcagctt caccctgccg tccgcctgct tcacgctgcg tccctccccc
    22501 aatccccggg tcattttcgc cagtgacaga cgggctgacg gggaaatgag tggcgttcgc
    22561 ctggctctgc ccggagagac aggcacgctg ataacaacgg ccacctggca ggtcaacgtg
    22621 ccggagcggc ctccttttga tatacagcat gtcattcact ggctcctgcc ctcgcctctc
    22681 acggcgctga tgtccgacaa cacctggctg tggccggata gccccggcac accggcactg
    22741 acggcgggag actggccggt aatggaaaca gataccccga cgctgaaacg cgtgaagcgt
    22801 cgtaccttca cgctcatcga taaccgcaac cgtcagggat ggatcacccg tcgcttccag
    22861 tgcttcccgc tggctccgct gccggaatca cacagtcacc gcgtaccaga catcctgtat
    22921 cccctgaaaa cggagaaaaa agaatgcaaa gacaaccagc aaccacactg cttgcactcc
    22981 tgataggctg tacggttatc ccgtccaccc acgcctatcc tgtgaccgta gtggccagcc
    23041 agcctgtcac cacacaaatc atgccggagc tggccaccat acagggcatc atggaggaaa
    23101 tggtccgtat gcagacggcc accggcacag ccatcaccca gaactcagaa aaactggcca
    23161 ccgtcattgc ccaggacggg caggccaccc gtcagcagat gatattcagt aatgaaaccc
    23221 gccggcttga ggaagcccgg aagagcttca gcgtgccgga ctccatctgc agtgaatccg
    23281 cctccggagt tgcagctgaa agtcgccgtg cagcagcgtc tgcggctgca cgtctgagtc
    23341 agggaggagg cgtcagcagt aaacccatcc gtgaacgtct ctcccgggca gcagactcac
    23401 caacccgcga ggcatatgac agtgcaggca ttcatgccgg ttactgcacg gaagctgaat
    23461 atgcccgctt tggcggaacc gatgtctgcc ctgccgtggg cgagctgccg ggcggagaca
    23521 gccaggtgcg atcgctctat cagggtgcag gcacagcaga tacccctgcc gccctcacct
    23581 gggatcagaa acagattgat gctgccacgg cttacatgaa aaacaccgcc agaccgtcag
    23641 cgggtcgtgc cccggggaaa ggtgaagtgg gaacacagac cgggcgcacg tatgtgggcc
    23701 tgcagaatga atacaacggc atcatcgatg ctgcttctca tccgcaactg tcactgatag
    23761 ctgacagtac ccctaatgag gccacccgtg gagcgctgac tgaagccctg cagtcaccat
    23821 ccgctgcggc atattttgac cggaccgcat catcagaggc ccgcacccgt ggtcacatga
    23881 gccagcggga gtttgaggcc tttgaagccg gcagacgcta tgcaaacacc gactggcagc
    23941 aggatctgca gggcatggaa ggcgataacc ttctccgtga actgctgcgc actaccgccc
    24001 tgctgaactg gcagatgaac gacctgaaag agcagatacg ccagggtaat gttatcgccg
    24061 ggcagcagct ggcactggcg gcacgacagt attacggaca gcgtctcggt gaactgtcac
    24121 aggccatgag ccaggggagc gtaagatgag agacgacaac agcaccgaca aaaaaaaacc
    24181 ggccccccgt ctccgccgca tcggtgacat cgggataaac ctgttcgcac cactggcaga
    24241 aacccggtgg atgctgcgca gctgccgcca tatgctgggc cagcataaaa cgcgcctgaa
    24301 gcgcctcatg cccgaccggc aaccggagag tccggtctgt atgacctggg aagaagccgt
    24361 cagggccagt ggccttacgg tcaacgaact ggatcggcgt ctgcgacgcc gcaggatgtt
    24421 ctggcggaca ggattctggc tgatgatgat accggtactt ctgctgtgcg gcatggccct
    24481 tgctgccaca gcgcttccgg ccatcaccct gatacgtata ctggcctgcc tgttactgat
    24541 gagtgccatt gcagcactgt gtgcctcaaa agccctgatt gcgtcatacc gcctctggca
    24601 gctgaatgaa cgtcgggtca gcgaggacga acagggcaca ttccccgatt acctgcaggc
    24661 ccggcacggc tggaaacagg ccacatggct ggccattacc caccggcagt actgactgtc
    24721 cggtctgcaa tttcttttcc tcattccggg ggctgatgcc cgggcatccc cttcggttcc
    24781 ggagttaccg tgaaaatcat acccagagca ctgagtgcag gtctggcgct ggctgccgta
    24841 cctgcacagg ctttcgtcac ctatcaggac attgtgagtg ccgccaccaa tccggatgac
    24901 ctgtcgcgcc aggcactggt caccattttt ggtgatgtgg tcacaaatcc cctgacagcc
    24961 agcagcaaca ccatcattgg taacctgttc atggtgttta acgcaattat cgccacgatg
    25021 gggatagtct ggtttctgtt tattggtatc cgtcatgctg tccgcacggg acaccagggc
    25081 agtgtcttta acaacggacg ggacgtcgtc ggcatactca gtgttgtgag tggatttttg
    25141 atgattgtgc ccaccgcttc cggctggagt ctggcgcaac tggtcatgct gtggggcgca
    25201 tccatcatgg gcatcggttc cgccaatatc atggttcaga cagcggcaga aaacattgct
    25261 gaaggctatt caatgaccgt acagccagta catgtctcca cccgcacggc agcacgggga
    25321 attctggaga tggaactgtg caaacacgcc atgaatacgg gcctcgatga ctttaaccgt
    25381 accgcacgtt catcaacgcc gctcatgagc gaatcctcac ggacagagaa tggcagatat
    25441 accgtcaccg tctcaaatgg cagcgccacc tgcgggagtg tgagtctctc cgtgaaagga
    25501 aacggcagta acaagcagtc cgcgctggcc cattttttca atcccttcat tgaaacggaa
    25561 tatcaggggg ttctgacggc acagcgctcc gccatggata ccatgctccg tgacctggac
    25621 agcgcggctc aggaatttgt gtcggcatac cggacccggc gcgacacggg taacggcaac
    25681 ctgccggata ttgaaagccg tattcagaag gcagccaacc ggtatgaaga aacggtgcag
    25741 aaggcgttgc cggcagataa cgcagaaact gagcgcaggg agcagctgaa atcctacctg
    25801 accacctacg gctgggttgc cctgggtgcc tggtaccaga cctttgccac cgccaaccag
    25861 cgactggaag acctggccaa ccgcgctcct actgtgagtg gcgtctcgtc actgggcgaa
    25921 gccggggata cggagttcct gaaggaagtc aagggggctt accaggcaca gctactgaac
    25981 tcaccatata ctcctgcgct gggaaatcta acatcttctg atgagatata tgctgccaat
    26041 acaaatgatc cccaaagtgc aattataaag ttaatgtcac cggactttac aaaactgaca
    26101 tataaaatcg caactgtata ttctggtaca ggaactacat cctatcaggc aaatcccctg
    26161 ctaaagatga aagacatcgg tgattacaca atggtaacaa ccgaaaccat ctgggcgggt
    26221 tataccaccg tcagggtact ttcctcggct ggcagcaact ccgtttttgg ccgactggtc
    26281 aatgccgtca gcggcttatc tgacgccgca aaggcttttc tggaagcggc cgcaccacca
    26341 ctctatttcc tgctgttttt gctgttctgt gccggttttt cgttgtccat ttacctgccg
    26401 tttatcccgt ttatcttctg gatgaccggc atcggtaact ggataatcag cgtgctgatt
    26461 ggatgcacag ccggtcccct gtgggccgcc acccatctgg gaacaagcca ggaccgggga
    26521 agccgggctg cttacggtta tatttacctg atagacagta tgatcagacc gctgctgatg
    26581 gtattcggat tcttttttgc atcggtcgcc atcgtggccg gcggcacaat actgaatgcg
    26641 ctgtttgctg ctgcgctgat gaatgtccag ataaactctg tgacgggcgt gttcagcatg
    26701 gcgggatttt tgatgattta tgcccgagcc tgtaccacgc tggttgcggc catttttgca
    26761 cttcaggctt atctgcctga ccatgtaatt aattttctgg gcgggcgtga cggtgttaat
    26821 atgctgggaa atatggtttc ttcagtcaaa gatattattg ccggaggtaa taccaatatg
    26881 cgcagaacac ctggcgttcg ggaagataga ctgaaagata ttaaaggaga tgataaagac
    26941 ggaataaaac aataaaataa aaaataccga aaagccaata aaattgtatt gccatattca
    27001 cctgaagaga tataaaatat attcaggtga atatggaggt ttattatgag cacaacaaaa
    27061 agcagatatc cttcctggtg ggcatattat taccttaccc gcaacgctta ttttttaatt
    27121 ggagttccat ttttaatttt ttgtgctatt gcttttacag cattaagtct agatatctat
    27181 tcgactaaat atgattatat atatgcatat ggaagttggg cgttactcat aatcccatca
    27241 ctctggctat atctgagaac cagggcgaag aaaaagaaag tccagcaggt tgttcagcag
    27301 ataaaagaaa gcagtccctt tgcgccgacc agcgattatg agcaactgtc attctcgaag
    27361 agttgttatt tcgggatcga cattaaaaac ggcaccatgc tgtatgtgcg catttatccg
    27421 aacaatgtga tggatgtgat tggtctggat attcacaact ttacccgcac ggttgctgaa
    27481 gacggcaagc tggaaatcca caccacctat gtgagtctgc cgatgattcc tcttgagatc
    27541 tccggcatct cagcaaggac gctggccaac accatgcaca ccatggctgc acgtggatat
    27601 gagtacaagg aacgtttccc acagatgatc cggtatcggg ttaaagagtg ggaaaaagtt
    27661 gccggtgttc ctgttgcaga agtattttga ggtagctatc aactgttaga cgataatccg
    27721 tcagccggtt tctctgaacc ggctttttct tttcaggcaa aatgcctgtc tgccgtccct
    27781 gtatcagact gtaattagca caatacggca atttgccgtt cagtatattc aggaagtaca
    27841 aatcatgcca tctgcaacac aaactgcccg actggaagca aggatcagca cagaactgca
    27901 tgctatgctg aaacgcgctg cagaaatcca ggtaaaaaag ggcgcattga ggtttgcttt
    27961 cgcaacaatc cggcggcaga tttcctgccg ccatgttgcc cgttaacgtt taacttcgta
    28021 ggctaacgtt gccacaagca ctgtgtttcc ctgctcgaca cggaatccgc aaagcgaatc
    28081 cctcaccatc cagacaaaac acagtatcgt cacacagacg acaattaaca ttattaaaaa
    28141 cgttcgttgt ggcatcgcag cccctccatt gcctttcggc ggttatcggg ctactataat
    28201 gttgttcatg cattacagta gagcccttgg ttgattgata aaaaatctcc aggggctttc
    28261 tgctgcatgc cgtccacaaa acgctttcgg catacagcct caagcgcccg ccgctattct
    28321 aatcgatttt cagtctgcca caatcgtttt ccacctaatg acatgttatg cacaacagta
    28381 tttttacggg aaactacacg gcaaggattc ccggaacacg ttcattattt tatggttaca
    28441 gacatcatgt taaatccgga agtaataatg acctggaagg aaatactatg agtaacgaat
    28501 atcaaagcac cagtataaac ccggatgttt ttgaacaatt ttttaccctc ctgaatacac
    28561 actgtaaatc atcagaagct gcacttgcca tgctgagtac actctgctac gaactgatga
    28621 ggaggagtgg gatccattca ctggacagcc tgatgctcaa cggagaaggt atattgatac
    28681 aattacaggg ggctgatatt cgcgaaaaaa caggtcagca tattcactga tccaggtatg
    28741 ggctgaaaac agtgtcagcc tgaaataaac gctcaatgcc tcatacacat ggggcattga
    28801 gcacggtcat caataatctt tattattttt ctgattcagc atttccggtc agtatcggct
    28861 cttctggcaa agacagtacc ggaacgtcac gttcaccatt gaatacaaaa acactttcag
    28921 cgaaatcatt ctgtaacaaa gaaaaactta acggcagatt tttggtttgt atccctgtga
    28981 tccattgaaa aatctcggga aaacgacgtg cactgatatg cacatgattg aggtggtgct
    29041 cagtaatatc actggccatc atcatgagag gtacatcgta tcccgaacgc aaacctggcg
    29101 catgatgcac aggggtgctg tctgaactga cggattgccc atgatcagaa aaatacagca
    29161 tggcaaaatc atcgccatgc tctgtcgtca tgttataaat tgcctgaaga aaccgatcca
    29221 gcttaagcaa tgttgataaa taacaggata ctttatttcc gaataattcc ctgaacggct
    29281 gtgcatcatt aaaaagtctg tcacagggat taggatggga ccccagcata tgaatgaaaa
    29341 tcacttttgg agaagacgaa ttaac
//
LOCUS       DAPOXO010000067        28613 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPOXO010000067 DAPOXO010000000
VERSION     DAPOXO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28613
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.067"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..221
                     /locus_tag="ROH59_003413"
     CDS             <1..221
                     /locus_tag="ROH59_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDX4805856.1"
                     /translation="GTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVN
                     FMQGYWISRPLPLDDFVRWLKKPYTPQW"
     gene            303..2117
                     /locus_tag="ROH59_003414"
     CDS             303..2117
                     /locus_tag="ROH59_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX4805857.1"
                     /translation="MIVRILLLFIALFTFGAQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKISDPLATPPLASGPYRITSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYNTWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPPEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPVYSLGIDTWWYDVNKATKLPSARQQGE"
     gene            2118..3212
                     /locus_tag="ROH59_003415"
     CDS             2118..3212
                     /locus_tag="ROH59_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HDX4805858.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNAGVLPGAGGEGVRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            3212..4237
                     /locus_tag="ROH59_003416"
     CDS             3212..4237
                     /locus_tag="ROH59_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4805859.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLLLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            4239..5828
                     /gene="yejF"
                     /locus_tag="ROH59_003417"
     CDS             4239..5828
                     /gene="yejF"
                     /locus_tag="ROH59_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HDX4805860.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVVNDVSLHIEAGETLALVGES
                     GSGKSVTALSILRLLPCPPVEYLSGDIRFHGESLLHASDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMQNGRCVEKNNAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSHGSIVFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSAAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG
                     PCARVFAAPQQEYTRQLLALS"
     gene            complement(5832..6176)
                     /locus_tag="ROH59_003418"
     CDS             complement(5832..6176)
                     /locus_tag="ROH59_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805861.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
     gene            complement(6510..7700)
                     /gene="bcr"
                     /locus_tag="ROH59_003419"
     CDS             complement(6510..7700)
                     /gene="bcr"
                     /locus_tag="ROH59_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HDX4805862.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVACALAQTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILAVAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNILFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCATSSILFCLYASR
                     PKKR"
     gene            complement(7728..8423)
                     /gene="rsuA"
                     /locus_tag="ROH59_003420"
     CDS             complement(7728..8423)
                     /gene="rsuA"
                     /locus_tag="ROH59_003420"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HDX4805863.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            8573..10333
                     /locus_tag="ROH59_003421"
     CDS             8573..10333
                     /locus_tag="ROH59_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDX4805864.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSVQSVAR
                     NLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMIFAATVEHAKEIVGLLPAED
                     AALITGDTPGSERDVLIDDFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDTILVDPDDMLKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERF
                     RLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADVLAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRRAHELRG"
     gene            10458..10742
                     /gene="rplY"
                     /locus_tag="ROH59_003422"
     CDS             10458..10742
                     /gene="rplY"
                     /locus_tag="ROH59_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HDX4805865.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAVELDH
                     DKVMNMQVKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLLHIDFVRA"
     gene            complement(10881..11888)
                     /gene="yejK"
                     /locus_tag="ROH59_003423"
     CDS             complement(10881..11888)
                     /gene="yejK"
                     /locus_tag="ROH59_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HDX4805866.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            12070..12297
                     /locus_tag="ROH59_003424"
     CDS             12070..12297
                     /locus_tag="ROH59_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HDX4805867.1"
                     /translation="MPQISRYSDEQVEQLLAELLNILEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            12317..14077
                     /gene="pbgA"
                     /locus_tag="ROH59_003425"
     CDS             12317..14077
                     /gene="pbgA"
                     /locus_tag="ROH59_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HDX4805868.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            14152..14228
                     /locus_tag="ROH59_003426"
     tRNA            14152..14228
                     /locus_tag="ROH59_003426"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14186..14188,aa:Pro,seq:ggg)
     gene            complement(14339..15282)
                     /locus_tag="ROH59_003427"
                     /pseudo
     CDS             complement(14339..15282)
                     /locus_tag="ROH59_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247409.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            15602..16249
                     /gene="narP"
                     /locus_tag="ROH59_003428"
     CDS             15602..16249
                     /gene="narP"
                     /locus_tag="ROH59_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HDX4805869.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            complement(16284..17336)
                     /gene="ccmH"
                     /locus_tag="ROH59_003429"
     CDS             complement(16284..17336)
                     /gene="ccmH"
                     /locus_tag="ROH59_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis thiol:disulfide
                     oxidoreductase CcmH"
                     /protein_id="HDX4805870.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVPEGKRAGYVVYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSPQESK"
     gene            complement(17333..17890)
                     /gene="dsbE"
                     /locus_tag="ROH59_003430"
     CDS             complement(17333..17890)
                     /gene="dsbE"
                     /locus_tag="ROH59_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HDX4805871.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
     gene            complement(17887..19830)
                     /gene="ccmF"
                     /locus_tag="ROH59_003431"
     CDS             complement(17887..19830)
                     /gene="ccmF"
                     /locus_tag="ROH59_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis heme lyase CcmF"
                     /protein_id="HDX4805872.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGG
                     LLCLFDPRYRKRVNPQKTAPEAA"
     gene            complement(19827..20306)
                     /gene="ccmE"
                     /locus_tag="ROH59_003432"
     CDS             complement(19827..20306)
                     /gene="ccmE"
                     /locus_tag="ROH59_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HDX4805873.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            complement(20303..20512)
                     /gene="ccmD"
                     /locus_tag="ROH59_003433"
     CDS             complement(20303..20512)
                     /gene="ccmD"
                     /locus_tag="ROH59_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HDX4805874.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            complement(20509..21246)
                     /gene="ccmC"
                     /locus_tag="ROH59_003434"
     CDS             complement(20509..21246)
                     /gene="ccmC"
                     /locus_tag="ROH59_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HDX4805875.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSILGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            complement(21288..21950)
                     /gene="ccmB"
                     /locus_tag="ROH59_003435"
     CDS             complement(21288..21950)
                     /gene="ccmB"
                     /locus_tag="ROH59_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HDX4805876.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            complement(21947..22564)
                     /gene="ccmA"
                     /locus_tag="ROH59_003436"
     CDS             complement(21947..22564)
                     /gene="ccmA"
                     /locus_tag="ROH59_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HDX4805877.1"
                     /translation="MLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLL
                     RLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDG
                     DTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
                     GVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAA"
     gene            complement(22583..23185)
                     /gene="napC"
                     /locus_tag="ROH59_003437"
     CDS             complement(22583..23185)
                     /gene="napC"
                     /locus_tag="ROH59_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HDX4805878.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            complement(23195..23644)
                     /gene="napB"
                     /locus_tag="ROH59_003438"
     CDS             complement(23195..23644)
                     /gene="napB"
                     /locus_tag="ROH59_003438"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HDX4805879.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQDRMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            complement(23641..24504)
                     /gene="napH"
                     /locus_tag="ROH59_003439"
     CDS             complement(23641..24504)
                     /gene="napH"
                     /locus_tag="ROH59_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HDX4805880.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVIILVGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AATDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            complement(24491..25186)
                     /gene="napG"
                     /locus_tag="ROH59_003440"
     CDS             complement(24491..25186)
                     /gene="napG"
                     /locus_tag="ROH59_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HDX4805881.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            complement(25193..27679)
                     /gene="napA"
                     /locus_tag="ROH59_003441"
     CDS             complement(25193..27679)
                     /gene="napA"
                     /locus_tag="ROH59_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic nitrate reductase subunit alpha"
                     /protein_id="HDX4805882.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            complement(27676..27939)
                     /gene="napD"
                     /locus_tag="ROH59_003442"
     CDS             complement(27676..27939)
                     /gene="napD"
                     /locus_tag="ROH59_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HDX4805883.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFTGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            complement(27929..28423)
                     /gene="napF"
                     /locus_tag="ROH59_003443"
     CDS             complement(27929..28423)
                     /gene="napF"
                     /locus_tag="ROH59_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HDX4805884.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGSYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDLQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
BASE COUNT         6928 a         7933 c         7175 g         6577 t
ORIGIN      
        1 tcggtacgga aacgatcact tcacccgtac ttgacgcggt gctgacgctg gcgaaacgtc
       61 tcaatatgct gacagttgct gaaggggtcg aaacgccaga acaggcacga tggctaagcg
      121 aacgcggcgt taatttcatg caaggctact ggattagtcg cccgttaccg ctggacgatt
      181 ttgttcgctg gctgaagaaa ccgtatacgc cgcagtggta aggtgtgctt acgtccctta
      241 ttattcatag tgaaagcatg ccggattgcg gctaatgatg agtaaaagga aatccgttgc
      301 agatgattgt gcgcatactg ctgctgttta tcgctctgtt cacctttggt gcgcaggcgc
      361 aggctatcaa ggaaagctat gcctttgcag tactgggcga accccggtac gcatttaatt
      421 tcaaccattt tgattatgtg aaccccgccg cgccaaaagg tgggcaaata acgttgtctg
      481 ccctcggcac cttcgataat ttcaaccgct atgcactgcg cggcaatccg ggcgcacgca
      541 ccgagcagct gtacgacacg ctatttacga cttccgatga cgaaccaggc agttattacc
      601 cgctgattgc tgaaagcgca cgctatgctg acgattattc ctgggtggag gtcgctatta
      661 atccacgcgc ccgttttcat gatggttcgc ccattactgc ccgcgatgta gagtttactt
      721 ttcaaaaatt tatgaccgaa ggcgtgccgc aatttcgtct ggtctacaaa ggcaccaccg
      781 tcaaagccat tgcgccgtta accgtgcgca ttgagttagc taaacccggc aaagaagata
      841 tgctgagtct gttttcgctg ccggtatttc cagaaaagta ctggaaagat cacaaaatta
      901 gcgacccgct cgccacgcct ccgcttgcca gtggtccgta ccgcattacg tcctggaaaa
      961 tggggcaaaa tattgtctat tcccgcgtga aagattactg ggcagcaaac ttaccggtaa
     1021 accgtggacg ctggaatttc gacaccattc gctacgatta ttacctcgat gataatgtcg
     1081 cctttgaagc gtttaaagca ggagcctttg atttgcgtat ggaaaacgac gccaaaaact
     1141 gggccacgcg ctataccggt aaaaatttcg ataaaaaata catcatcaaa gatgagcaaa
     1201 agaacgaatc agcccaggat acgcgctggc tggcgtttaa tatccaacgt ccggtattca
     1261 gcgatcgccg ggtgcgggaa gcgatcactc tcgcctttga ctttgaatgg atgaacaagg
     1321 cgttgtttta caatacctgg agtcgcacga acagttattt tcagaatacc gaatatgcgg
     1381 ccagaaatta ccccgacgcc gcggaactgg tgcttctggc accaatgaaa aaagatctac
     1441 cgccagaagt cttcacgcaa atctaccagc cgccggtatc caaaggcgat ggctacgatc
     1501 gtgacaacct gttaaaagcc gacaaacttc tcaacgaagc aggctgggtg ctgaagggtc
     1561 agcaacgcgt taatgccaca acaggtcagc cactcagctt tgaattattg cttcccgcaa
     1621 gcagcaatag tcagtgggta ttgccgttcc agcacagcct gcaacggctg ggtatcaaca
     1681 tggacattcg caaggtggat aactcgcaaa tcaccaaccg catgcgcagt cgcgactatg
     1741 acatgatgcc gcgcgtatgg cgggcgatgc cgtggcccag ttccgattta cagatttcct
     1801 ggtcatcgga atatatcaat tccacttata atgcccccgg cgtgcaaagc ccggttatcg
     1861 actcgctgat caaccaaatt attgccgcgc agggaaataa agaaaaatta ctgccgttgg
     1921 gacgagcact ggatcgcgta ttaacgtgga attattacat gctgccaatg tggtacatgg
     1981 cggaagaccg tctcgcctgg tgggataaat tctcccaacc cgctgtacgc ccagtttaca
     2041 gcctgggtat tgatacctgg tggtatgacg ttaataaagc gacgaaactg ccgtcagcca
     2101 gacaacaggg agagtagatg ggcgcttatc tgatccgccg tctgttgctg gtgatcccaa
     2161 cgctatgggc gattatcact atcaactttt tcatcgtgca aattgcgcct ggcggtccgg
     2221 tcgaccaggc catcgccgcc attgagtttg gcaatgccgg agtattaccc ggcgcaggcg
     2281 gtgaaggtgt tcgcgccagc catgcgcaaa cgggcgtcgg caatatcagc gacagtaatt
     2341 accgtggcgg acgcggatta gatccagaag tgatcgccga gatcactcat cgctacggtt
     2401 tcgataagcc gatccacgaa cgttacttca aaatgctctg ggactacatc cgttttgatt
     2461 ttggcgacag cctttttcgc agcgcctcgg tgctgacgct gattaaagac agtctgccgg
     2521 tctccatcac cctcggattg tggagcacgc tgattatcta tctggtgtcg attccgttag
     2581 gcattcgcaa agctgtttat aatgggagcc gttttgacgt ctggagtagt gcatttatca
     2641 tcatcggcta cgccattccg gcctttttgt ttgccatcct gctgattgtc ttcttcgcgg
     2701 gcggcagcta tttcgatctg ttccctctgc gcggcctggt ttccgctaac tttgattcgc
     2761 tgccgtggta tcagaaaatc accgattatc tgtggcatat cacgctgccg gtgctggcga
     2821 cagtgattgg cggctttgcg gctctgacca tgctgacaaa aaactcattc cttgatgaag
     2881 tgcgtaagca atacgtggtg acggcacgtg cgaaaggggt aagtgaaaaa aatattctct
     2941 ggaaacatgt gttccgcaac gccatgctgc tggtgattgc cggttttccg gcgacgttta
     3001 tcagcatgtt ttttaccggc tcgctgctga ttgaggtgat gttttcactc aatggtcttg
     3061 gcttactggg ctacgaagcg accgtctcgc gcgattatcc tgtaatgttt ggtaccttgt
     3121 atattttcac cctgattggc ctgctgctga atattgtcag tgatatcagc tatacgctgg
     3181 tcgatccgcg tatagacttt gagggacgtt aatgtcgcga ctcagccccg tcaatcaggc
     3241 ccgttgggcg cgttttcgcc ataaccgtcg cggctactgg tcgttatgga ttttcctcct
     3301 cttgtttggt ttgagtttgt gttctgaact tatcgccaac gataaaccgt tgctggtgcg
     3361 ttatgacggc agttggtatt tcccgttgtt gaaaaactac agcgaaagcg attttggcgg
     3421 cccgctggca agtcaggctg attatcagga cccgtggctg aaacaacgac tggaaaataa
     3481 cggctgggta ctgtgggcac cgattcgctt tggtgctacc agtatcaact ttgctaccga
     3541 taagcccttc ccttctccac cctcccggca aaactggctg ggaacggatg ccaatggcgg
     3601 cgatgtgctg gcgcgcattc tctatggcac gcggatctca gttctgtttg gcctgatgct
     3661 gaccctctgc tccagcgtga tgggtgtgct ggcgggggcg ctacaaggct attacggtgg
     3721 taaagtcgat ctctgggggc aacgttttat tgaagtatgg tcggggatgc cgacgctgtt
     3781 tttgattatt ttactttcca gcgtcgtaca gcctaacttc tggtggctgc tggcaattac
     3841 tgtcttgttt ggctggatga gtctggtcgg cgtggtgcgg gcggagtttt tacgtacccg
     3901 taatttcgac tacatccgcg cggcgcaggc gcttggcgtc agcgatcgca gtatcatcct
     3961 gcgtcatatg ttgccaaatg ccatggtcgc taccctcact tttttaccgt ttattttatg
     4021 tagttcgata accaccctga cctcactcga tttcctcggc ttcggtctgc cgctcggttc
     4081 accgtcactc ggcgaactcc tgttacaagg gaaaaataac cttcaggccc cgtggcttgg
     4141 gatcaccgcc ttcttatcgg tggcgatatt gttgtctttg ctgatcttta ttggtgaagc
     4201 cgtccgcgac gcatttgatc ctaataaggc ggtgtagcat gacgcaaact ctgttagcga
     4261 ttgaaaattt gtcggtgggt tttcgccatc agcaaactgt tcgtaccgta gtgaatgatg
     4321 tgtcactaca cattgaggct ggcgaaacgc tggcgctggt aggtgagtct ggttcaggta
     4381 agagcgttac cgcgctgtca attttacgcc tgctcccttg cccgccggtt gaatatctct
     4441 ccggcgatat tcgttttcat ggcgaatcgc tgcttcatgc cagcgatcaa acgttgcgcg
     4501 gtgtacgcgg taataagatc gccatgattt ttcaggagcc gatggtgtcg ttaaatccat
     4561 tacataccct ggaaaaacag ctttatgaag tgctttcact ccaccgcggg atgcgtcggg
     4621 aagcggctcg tggcgaaatt cttaactgcc ttgatcgcgt cggtatccgc caggcggcaa
     4681 aacggctgac agattatccg catcagctct ccggcggcga acgccagcgg gtgatgattg
     4741 cgatggcgct gttaacgcga ccggaattat taattgccga tgaaccaacc accgcgctgg
     4801 acgtctctgt ccaggcgcag attttacagc tgttgcgcga actgcaaggc gagctgaata
     4861 tgggtatgct gtttattact cataacctca gcattgttag aaaactggcc caccgcgtgg
     4921 cggtaatgca aaacggtcgc tgtgtcgaga aaaataacgc cgctacgcta tttgcctcac
     4981 ccactcatcc ttacacacaa aagctactca acagtgaacc atctggcgac ccggtgccat
     5041 tgccagaacc tgcctcaacg ttgctggatg ttgaacaact tcaggttgcc ttccccattc
     5101 gcaaagggat tttgaagcgc attgtggatc ataatgtggt ggtgaaaaac atcagtttta
     5161 cgctacgggc gggtgaaaca ctgggtttag tgggcgagtc cggttccggg aaaagcacga
     5221 cgggactggc gctgctgcga ctgattaact ctcatggcag catcgtcttt gacggtcagc
     5281 cactgcaaaa tttaaatcgc cgccagctgt tacctattcg tcatcgcatt caggtggtat
     5341 ttcaggatcc aaactcctca ctcaacccac gactcaacgt tttgcaaatt attgaggaag
     5401 gcttacgggt tcaccagccg acgctttctg ccgcacaacg cgaacaacaa gtgatagccg
     5461 tgatgcatga agtgggatta gatcctgaaa cacgccaccg ttatccggcg gagttctctg
     5521 gtggtcagcg gcaacgtatt gcgattgcca gggcgttaat tcttaagccc tcgctgatca
     5581 ttcttgatga accaacatca tcactcgaca aaacggtgca ggcgcaaata ttgacgctat
     5641 tgaaatcatt gcaacaaaag catcaactgg cctatttgtt tatcagccac gatttgcacg
     5701 ttgtccgcgc gttatgtcat caggttatcg tactgcgaca aggggaagta gtggaacaag
     5761 gaccgtgcgc gcgcgtgttt gccgcaccgc agcaggagta tacgcgtcag ctactggcgt
     5821 tgagctgacg cttaaaaagg attgtagttt gaaaagggtt cggcaattgc cacaccaaaa
     5881 tttttcaatc ggcatgttgc agcaaattcg tcctggcgat ttacaaacag gcacggctca
     5941 ccttcacact ccagcaccga acatggaact tcgatgtcgc ttaacgcctg gcttagtttg
     6001 tacatcaccg accatgcatt atcaccatcc gggctaagca atttaagcgc caccaggctg
     6061 ttgtcaccgc acggtccatt ttgcggaatc ggttcaacct tcgaacctgc gaaaccagca
     6121 gaccagcgat agttctgcgg cagtcgatgg acgattgaga gttgtaatga agtcacttat
     6181 tttccccgga agtacatttt acttcacaat ttatttacat caattttaac acatcatcaa
     6241 caatccgtct ttatacagat cgtaaagatt gatgcctcgc ctgcgtggcc tatatggctc
     6301 tgatttaaat aatatctgcg ggcgtggtca cgtttgcggg gctatatgta cccgtttctg
     6361 cgatctaact caaccttttt aactacaatg atgtgacttt ttacataaat tgattttaca
     6421 taaaataaac atatatcggg ggaatgatag atttgtggtt gacatgcatc aacaaaggaa
     6481 gccttttagc ttcctcgttg tgcaatagat caccgttttt tcggccgact ggcgtacaga
     6541 cagaagagaa tggagctggt tgcacagaat gcaattgacc aaatcatcgg ccatgcagag
     6601 ttaaaggtcg caagagaaag taatgcgcca acaattgccc ctatgccgaa acggaaggtt
     6661 cctgccagcg aagatgccgt tcccgccata tggggaaact catcaagaat gaccgccatc
     6721 gcattggatg acaccatcga cacgcagccc acaaacgccg caacgccaac caccagcgac
     6781 cagaatccca gccccagcag tgcactgatg accatccacg ctgccataat aaactgtatc
     6841 cacaaccccg agcggaacat atttaacgcg ccaatacggc ggacgaagcg gctgttaaag
     6901 atggtcatca cgaacagaaa aagaatgttt agcgcaaagt aataaccaaa gttttccggc
     6961 gcgacgtggt tgatttcaat gtagacaaac ggtccggcgc ttaagaatga gaacatcccg
     7021 gcaaagctga aaccgctggc cagcatataa ctcaggacac gcttatgacg gaacagcgcc
     7081 gcaaagttac caatagtggt acgaatgtga aaaggctggc gacgctccgg tggtaaggtt
     7141 tctttgatca gaaagaagat cattgccgaa gccagaatcg ccgccacggc gaggatccag
     7201 aagatgtaat gccagctcag ccacaccagc acccagccgc caactatcgg tgccatcagc
     7261 ggtgcaatgg tcgtcaccag catgacaaac gacatcatcc gtgagaactc ttctttcggg
     7321 tagatatcac gcatcaaagc gttgataacc acgctggccg cagccgcagc cagcccgtgg
     7381 aagaaacgca tcacaatcag ctgatcgatg gtttgtgcca acgcacacgc caccgcggcg
     7441 gcggcaaaca ccagcgtacc gccaagaacc accggcttac gcccgaagct gtctgccatc
     7501 ggcccgtaga ttaactgccc caacgcaaag cccagaatat aagtactgag ggtcatctgc
     7561 gtactgcccg ccggtacacc aaactgcgct gaaattaccg gtagcgcagg cagatacata
     7621 tcaatcgaca gcggcatcaa catggccagc aggccaagga taaaaacaat agcaaacgac
     7681 gaatgctgtc gggtggtcac aacgggctcc tgaaagtcat tgaaaagtta gacgacgctg
     7741 gcaatttctt cttcagttaa cggacgatat tcaccggggg ctaaatcagc atccagcgta
     7801 ataccgccaa tacgttcacg atgcagctca accacatggt tacccacggc ggcgaacata
     7861 cgtttcacct gatgataacg cccttcgctg atggtcaaac gaacctgcgt tggggtaatc
     7921 acttccagca ccgccggctt agtgagatct ttttcgttat gcagctgcac gcctttagca
     7981 aattgctctg ccgtatcgtc agctacgggt gattccagcg tcaccagata ggtcttctcg
     8041 caatgatggc gcggggaagt aatgcggtgc gaccactgac catcatctgt cattagtacc
     8101 agaccggtgg tatcgatatc cagacgccct gcagcgtgca gtttccacgc taccggttca
     8161 tcaagaaaat agagcaccgt tgggtgatcc gggtcgtccg tggagcaaac atagccctga
     8221 ggcttattga gcatgaagta acgtggaccg tgttgctgcg ccagcgggtt gccatcgtaa
     8281 gcgacatcat gttcagggag cagtttgaac gctgcattac ggacgatttc gccatcgacg
     8341 gtgacacgat tgccgcggat ttcacgcccg gcaatagcac ggctaacgcc gagttgctgt
     8401 gcgataaatt tatcaagtcg catgtgtgtg attttgcctg taaaaaacgg aggtcgggta
     8461 atgacccgaa aatctgaact gttgtctgcc cagtatagcg gtctaataac ttccctcaag
     8521 ggaaaaagat ccgtggcata ctattagcag aataatctac ctacgcgaga ccatgatttt
     8581 tacactccgc ccatatcagc aagaagccgt ggatgccacg ctcaaccatt ttcgtcgtca
     8641 taaaacccct gccgtaatcg tgctgcccac cggtgcaggt aaaagcctgg tgatagcgga
     8701 actggcgcgg ctggcgcgtg gtcgcgtgct ggtgctggca cacgttaaag aactggtggc
     8761 acaaaaccat gcaaaatatc aggcgctggg gctggaagcc gatatttttg ccgccgggct
     8821 aaagcgcaaa gagagccacg gtaaagtggt atttggcagc gtgcagtcgg tcgcccgtaa
     8881 tcttgatgcc tttcagggtg aattttcgct gttgattgtc gatgaatgcc accgtattgg
     8941 tgacgatgaa gagagccaat atcagcaaat cctcactcac ctgaccaaag tgaatcccca
     9001 cttacgcctg ctggggctga ctgccacgcc ttttcgactg ggcaaaggct ggatctacca
     9061 gttccattat cacggcatgg tacgcggcga tgagaaagcc cttttccgtg actgcattta
     9121 tgagctgccg ctgcgttata tgattaaaca cggctatctg acgccgccag aacggctgga
     9181 tatgccagta gtgcaatacg atttcagccg cttgcaggca cagagtaacg gactgttcag
     9241 cgaagccgat ctcaaccgcg agctgaaaaa acagcaacgc attacgccac acatcatcag
     9301 ccaaatcatg gagtttgctg caacgcgcaa aggggtgatg attttcgccg cgacggtcga
     9361 acacgcaaaa gagatagtgg gattactgcc tgccgaagat gcagcactga ttactggcga
     9421 cacacccggc tctgagcgcg atgtgttaat tgatgatttt aaagcccagc gttttcgcta
     9481 tctggtcaac gtcgcggtac tgaccaccgg atttgacgcc ccgcacgtcg atcttatcgc
     9541 cattctgcgc cctaccgaat cggtgagtct ttaccaacaa attgtcgggc gcggtctgcg
     9601 cctggccccc ggcaagactg attgcttaat tcttgattat gcgggtaacc ctcacgatct
     9661 ctacgcgccg gaagttggta caccgaaagg caaaagtgac aacgttccgg tacaggtttt
     9721 ctgccctgcc tgcggttttg ccaacacctt ttgggggaaa acgaccgccg acgggacatt
     9781 gattgaacac tttggtcgtc gctgtcaggg atggtttgaa gatgacgacg gacatcgcga
     9841 acagtgtgac ttccgtttcc gttttaaaaa ttgcccgcaa tgtaacgctg aaaatgatat
     9901 tgccgcccgc cgttgccgcg agtgtgacac cattctggtt gacccggatg atatgttaaa
     9961 agcggcgcta cgactgaaag acgcgctggt attacgctgt agcggcatgt ctttgcagca
    10021 tgggcacgac gaaaaaggcg aatggttgaa aatcacctat tacgatgaag acggcgcgga
    10081 tgtgagtgag cgtttccgtc tgcaaacgcc cgcccagcga actgccttcg agcagctttt
    10141 tatccgcccg catacgcgca caccgggcat cccgctgcgc tggatcaccg ccgccgatgt
    10201 cctcgcccag caagccttat tgcgacaccc ggattttgtc gtcgcccgca tgaaaggcca
    10261 gtactggcaa gtgcgtgaaa aagtgttcga ttacgaaggt cgttttcgtc gggcgcacga
    10321 attacgcggt taatggtagt tttgattgat gtataaggcg attgagtata gaatctcgcc
    10381 cgcttttgca tacgcaaagc agatcactta cctgttgctg ggtcgcctgt agcaggatta
    10441 atttaagaga gaaagaaatg tttactatca acgcagaagt acgtaaagag cagggtaagg
    10501 gtgcgagccg ccgcctgcgt gccgctaaca agttcccggc aatcatctac ggtggcaaag
    10561 aagcgccgct ggctgtcgaa ctggatcacg acaaagtcat gaacatgcaa gttaaagctg
    10621 aattctacag cgaagttctg accatcgttg ttgacggtaa agaaatcaaa gttaaagctc
    10681 aggacgtaca gcgtcacccg tacaaaccga agctgctgca catcgacttc gttcgcgctt
    10741 aattgctgaa taagttgtaa aaaaccccgc tccggcgggg ttttttgtct ctgcaaatta
    10801 tgcctgatta cggtattgct attttttgca ggccagataa ggcgttcacg ccgcatctgg
    10861 cattcagaac acaaaaccga ttaattgccg ccagacgtcc ggcgctgcaa ttgatcgcgc
    10921 aagttcggcg gcgtgccttt aatggtcagg gtatcggttg ctggatccca gaagatgcgt
    10981 tcacctaaca gcatcgcatc aaagttaata gtcaagccac cgccgctacc ggcaaacttc
    11041 gtcaactgac gcagtgtgct acggtctgcc gggaagctct cttccagttc gtagcctttt
    11101 tcagccgcaa actccgtgaa gctcacttcg ctgacgcctg ccagctcttt cgacagcgat
    11161 tccagttcaa tctcttcacc tgcctgtagc tgctcattac agtagctata aacctgctgg
    11221 cgcacgttct gtcgctctgc tttatccagt tgtgcttcgg cagtgaaatc atcgaccgct
    11281 tgcaacagcc cacggttttg cgctttcgcg tttaaccctt cgctggcacc gaggaaatcc
    11341 ataaagaaat ccgccacttt gcgccctact cgccctttca ggaaagtgag atagcgggtc
    11401 gactctggat tggtttccca ctcggttaaa tcgatacgcg caacaatatc cgcatgattg
    11461 atatcaagat aatgggttgg gttgatgtcg agattttcgt taacacgcat actgctcagg
    11521 ttgctcagaa ctgccaccag cagatactcc accgccagat agcgatagtg gcaaaacagc
    11581 acgaatccac cgtcagcaaa aggatatttc gctaattcgt cacgcaggcg accggttgcc
    11641 gcgcggctaa atgccagaaa gtcctcttcg ccctgacgct gtaagcgcag cgtctgcgcc
    11701 agttcactct cttcgctaaa caagccgtaa gctttatttt tggcgctata gacccgatgc
    11761 agttctgcca ccatctcaac gacggtttcc gtcggttcca gcaatgaatc gcgcaacacc
    11821 agctcaaggt tctgctcatc acgcttgata agctggtgca gagcaatctg gttgatatcc
    11881 agactcatga taaactctcc tttaagaccg ggcggtattc aaccaccgcc ggttaagcga
    11941 cgcaataaaa gatggcggtc attttacaga aggcggcgta acgagaatga tttaacgcat
    12001 aaaaaagcag aaaaaaaacc gttgctacgg taatatgttg ccctttcatc aactaactga
    12061 tttcgattta tgccacaaat ttcccgctac agtgatgaac aggttgaaca attgctcgca
    12121 gagctgctca acatactgga aaaacataag gctccgaccg acctttccct gatggtgtta
    12181 ggcaacatgg tcactaacct tatcaacacc agcattgccc cggcccaacg ccaggcaatt
    12241 gccaactctt ttgcccgcgc cttacagtcc tctatcaacg aagacaaagc gcactaaggg
    12301 aaacagataa caggttatgg taactcatcg tcagcgctac cgtgaaaaag tctcccagat
    12361 ggtcagttgg gggcactggt ttgcactgtt caatattctg ctttcgctcg tcattggcag
    12421 ccgttacctg tttatcgccg actggccgac aacgcttgct ggtcgcattt attcctacgt
    12481 aagcattatc ggtcatttca gcttcctggt gttcgccacc tacttgctga tcctcttccc
    12541 gctaaccttt atcgtcggct cccagaggct gatgaggttt ttgtccgtca ttctggcaac
    12601 ggcgggaatg acgctattac tgatcgacag cgaagtcttt actcgtttcc atctccatct
    12661 taatcccatc gtctggcagc tggttatcaa cccagacgaa aatgagatgg cgcgcgactg
    12721 gcagctgatg ttcatcagcg tgccggttat tttattgctt gaactggtgt ttgcgacgtg
    12781 gagctggcaa aagctgcgca gcctgacgcg tcgtcggcgc ttcgcgcgcc cgctggccgc
    12841 attcttattt atcgccttta tcgcctcgca tgtggtttat atctgggccg atgccaactt
    12901 ctatcgcccg atcaccatgc agcgcgctaa cctgccgctt tcgtacccga tgacggcacg
    12961 acgttttctt gagaagcatg gcctgcttga tgcgcaagag tatcaacgcc gtcttattga
    13021 gcaaggcaat ccagacgccg tttccgttca gtatccgtta agcgaactgc gctatcgcga
    13081 tatgggcacc gggcagaatg tgctgttgat tactgtcgat ggcctgaact actcacgctt
    13141 cgagaagcag atgcctgcgc tggcaggttt tgctgagcaa aatatttcgt tcacgcgtca
    13201 tatgagctcc ggcaacacta cagacaacgg catctttggc ctgttttatg gcatctcgcc
    13261 aagctatatg gacggcattt tgtcgacccg tacgcctgcg gcgttaatta ctgcgcttaa
    13321 tcagcaaggc tatcagctgg ggttattctc gtcagatggc tttaccagcc cgctgtatcg
    13381 ccaggcattg ttgtcagatt tctcgatgcc gagtgtacgc acccaatccg acgaacagac
    13441 cgccacgcag tggattaact ggctgggccg ctacgcacaa gaagataacc gctggttctc
    13501 gtgggtctct ttcaatggca caaacattga cgacagcaat cagcaggcat ttgcacggaa
    13561 atatagccgg gcagcaggca atgtcgatga ccagatcaac cgcgtgctca atgcactgcg
    13621 tgattctggc aaactggaca atacggtggt gattatcact gccgggcggg gtattccgct
    13681 gagcgaagag gaagaaacct ttgactggtc ccacggtcat ctgcaggtgc cattagtgat
    13741 tcactggcca ggcacgccgg cgcagcgtat taatgcgctg actgatcata ccgatctgat
    13801 gacgacgctg atgcaacgcc tgctacatgt cagcacacct gccagcgaat attcgcaagg
    13861 tcaggatttg ttcaaccctc aacgccgcca ttactgggtt accgccgcgg ataacgatac
    13921 gctggcaatt accaccccga aaaagacgct ggtgctgaac aataacggta aataccgcac
    13981 ttacaactta cgtggtgaaa gagtgaaaga tgaaaaacca cagttaagtt tgttattgca
    14041 agtactgaca gacgagaagc gttttatcgc taactgatta attataaatc agttagcaaa
    14101 atatcttact tgcaatcggt gtggaaaacg gtagtattag cagccacgag tcggcacgta
    14161 gcgcagcctg gtagcgcacc gtcatggggt gtcgggggtc ggaggttcaa atcctctcgt
    14221 gccgaccaaa aatcccaaga aaaccaacct attgcggttg gtttttttat atctgcattt
    14281 aattcgataa acagaccgcg acacatcacg gcctgtttat tttctgttat cagaacgtcc
    14341 agaccacacc cgcctgagtt gtgctgcttt cttcacggga gaaacggctg tcgataccaa
    14401 gcgttagccc cgtcaatgtt tgctcaaagc cagcgcctgc atcagtggtc acgttgttgc
    14461 ggctgttaat tgccgaactc cacatcgccg tatcgtaatt aacgcctttt acgctaccaa
    14521 gacgcccacg cacggtgtcc agttctgcat caaataccag cggttgtgct gccgccatat
    14581 tcagcacatc cgtggttgaa gggggcattt gtgcgcgatt ctctgcgaga ctccagctat
    14641 ggttgccatt atccagcaag gtatattcat acgtactgat atcaacaacg cctccggcat
    14701 tgcccaacgt aaatgccgca tcaccgcgcc cgttgttacc agtgtaaggt tatctcctgc
    14761 tgccgggctg gcaccggtgt ccgtcacgaa tattttgaaa tcacctgttg ctttaacctc
    14821 cagtagccct cccttttcta taacggcaaa gacggcaatc ccatcttttt caacaattaa
    14881 gcgccctcct ttaatcgtgg gatcagtcgc cgcgccataa acctgtagca ctccattatt
    14941 gatcgtagtc tggtttaccg cgccacccat ttgaacaatt tgataaccat catttaatac
    15001 tgagtattct gcggtgccat ttatttcaat gtactgatat cccccgttaa tttcagtatt
    15061 actacttaca ccaaattctt atatatgctg ttctccgcca ggattgattt tcgtattatt
    15121 ggcggcccta caaaccagct ggatatcttt ttccaggaca acaccatcaa ctgtctcacc
    15181 atactcaaca gttgatgcca atgctatggg cgaatataac gctgtagcca ccagaacaga
    15241 tattgcggaa cgacaaagag aaacagaacc agattggtgc attaagcttt catcctatga
    15301 aattaattgc tgttaaaagc attggggaca gaaaataccc atagctccat acccggagtc
    15361 agtttttaaa aactgtttaa agaaatgcac aagtattgtg attgattttt tagttgtttt
    15421 tcctgatgag aagctgatgc aaaattccgt ctttataata aagatgatgc caaagcgaac
    15481 gacaaagttg tagttttcac tacatgtcca tacataaaat ggggtaacat tcacgcgcct
    15541 ggtagcgtta ccaacgctac gctcaaacat aatgattcta ataaaacctc aggagactac
    15601 tatgcctgaa gcaacgcctt ttcaggtgat gattgtggat gatcatccac ttatgcgacg
    15661 cggtgttcgt cagttactgg agcttgattc tggctttgaa gtggtcgccg aagcgggcga
    15721 cggcgcaagc gcgatcgatc tggcgaatag actggatatc gacgtgatct tgctggatct
    15781 caatatgaaa ggcatgagtg gcctggatac cctcaatgcc ttgcgcaggg atggcgttac
    15841 cgcgcaaatt attatcctga ccgtatcaga tgcctccagc gatgtctttg cactgataga
    15901 cgcaggcgca gacggttatc tgttgaaaga cagcgacccg gaagtgttac tggaagcgat
    15961 tcgtgccgga gcgaaaggca gcaaagtctt tagcgaacgc gtcaatcagt acttacgtga
    16021 acgtgaaatg tttggcgcgg aagaagaccc cttcagcgtg ctgacagaac gcgagctgga
    16081 tgttctgcac gagctggcac aggggctgtc aaataaacag attgcctcgg tgttgaatat
    16141 ttccgagcag acagtaaaag tccatattcg caatctgctg cgtaaactca acgtccgctc
    16201 acgcgtggcg gccaccattc tgttcctgca acaacgcggg gcacaataaa aatagcccga
    16261 tggcatcacc atcgggccac tttttattta ctctcctgcg gcgacaaatg ttgcatcgcc
    16321 tgcgcgatac tacgttcgat caccgcacgg cgagtatcgt tggcaggtaa gagtttcaac
    16381 atcatttccc acgcggcaac ggcttcgcca aatcgttgct gctcaaaggc attaaatgca
    16441 tacatgctta acacacggat attgctatgg tccgttctca ccaactggcg cagcagttcg
    16501 ccgccgaggc ggttgtcgtt gggatcagat gaacgtgtca acgcttcagc gtatcccagt
    16561 gcagcatcgc tgtttttcgg atcgaggcga tacgcagtgg cgtatgcatc ggtggcgata
    16621 ctggcgttac ccagcgccat gccaacgcgg cccaacataa tccagccttc tatatctccc
    16681 ggattttttt gcagttgagt acgcatcccc agcgcaaggc gcgacatctc ttcttcgttg
    16741 agcggatcgg ctttcggatc cagcgccctg tccagtaacg ccggagcctg tgccgtggcc
    16801 tgctgccaga ttttcacctg ctgataattg ccagtctggt agtagctgac gccagccaca
    16861 attaacgcca ccacaatacc cggcagataa acaacatatc cggcacgctt accttccggc
    16921 acgctttgtt ctggaaacgc ttccggcacc acgcgtaccc gacgccgcga acgggcgtat
    16981 atgacccaac cgccaatgcc aatagccact actggcagca cccacagcag cacggtcagc
    17041 ggcgttaacg gcggatcgta agtgacgaag ttgccgtaac gcgccaccat ataatcgaca
    17101 atctctttct tacttttgcc ttcctgcatc agttcataca ctttctggcg caggtcggtg
    17161 gcaatcatcg agttggaatc ggcaatgctg ttgttctggc atttcgggca gcgcagttct
    17221 tcagtgagct gacggaactg ttgttcctgt gcttcatctt taaactgcaa cacgtcgatg
    17281 gtcgccagcg ctgagccgga gatcatcagc atcagcacgc ccaataaaaa cctcattgtg
    17341 cggcctcctt actgtatttc tcccacagtg gcttgatctc ttcttcccag acgcgaggat
    17401 tgagatcgcc cgcatggcga tagcgaatga tgccgttgcc gtcaataagg aacgtttctg
    17461 gcgcgccata gacaccgaga tccagcccta acatgccgtc gccatcaaac aggcttagcg
    17521 cgtaaggatt gcccagctct ttcagccagc tgattgcctt ctggcgatcg tctttatagt
    17581 tcatgccgac cacgcggatg ccctgcgcag aaagctgatt cagatattga tgttccgcac
    17641 ggcaggtcgg acaccaggtc gcccagacgt taagcagcac tggtttgccc tgagtcagca
    17701 catccgcctg ataaaactgc cccggattgt ccagtgattc gaggcgaaac ttcggcactg
    17761 gcttgccaat gagcgccgat tccagattgg tcggatcatc cccttcggca ttacgcgcca
    17821 gctgccacag cagcgccgcg gcaatcgcca ggaagataat caacggaatt aacaatacct
    17881 tgcgcttcat gcagcctccg gcgcagtttt ctgcgggttc acgcgcttac gatagcgagg
    17941 atcaaacaga cacagcagtc cgcccaacgc catcatcagc ccgcccgccc aaatccagcg
    18001 aacaaatggt ttgtagtaaa gacgcacggc ccacgcgccg ttttccagct cttcaccgag
    18061 cgccgcgtac aggtcacgcg tgatgccacc gtcaatcgcc gcttcggtca tcatcgaccc
    18121 ggcagtgttg taataacgtt tttctgcata cagcactgtt tccggcttgc catctcgcgt
    18181 tacgccgata gtcgccacac cgccacgcca gtttggacca gtcacttctt tgacatcacg
    18241 gaaggtgaag cgatattcat gaatatcgac gctatcgccg gacttcatgc gcacatcacg
    18301 ctcaacgcta tagttctgac taaaagcaat gccaacaatt gtcactgcca gccccaggtg
    18361 agctgccacc atcccccaat aactgaaggt ggttttcgtg ccgcgtgaaa tacgcagcgc
    18421 agcttccgca attgccagca ccgcaatcca gcaggccatt gccaggccga gcaccgtcat
    18481 cgccacaact ttgctttcga acagccacgg caacagcagc gacagcacca gcgtagagat
    18541 gaaggcgata atcaacaaat tgcggatttt acgtgggcga tcgcgtcccc agcgcaccag
    18601 agggccgaca ccaagcagta gcgcaaacgg caccatcagc caggtaaaca tggtgttgaa
    18661 gaacggttcg ccaatcgaaa tactgcccag tcccagttgc ttgtgcacca gcggcagcaa
    18721 cgtccccagc aacaccacca gcatcgcggc taccagcaaa acgttgttcg ctaacagcaa
    18781 agattcccgc gaccacagcg cattgtttac gcgtgagcga actttgtgtc cacgcgcggc
    18841 aaacagcagc agcgaaccgc caatcaccag caccataaag gcgaggataa acataccgcg
    18901 cgccggatca gacgcaaacg cgtgtaccga taccagcacg ccggaacgca cgaggaaagt
    18961 ccccagcaga cacaacgaga aggcactgat tgccagcagt aatgtccacg ctttgaagct
    19021 ggcgcgttgt tcagtgaccg ccagtgagtg catcagcgca gtccccacca gccacggcat
    19081 aaacgaggcg ttttctaccg gatcccagaa ccaccagccg ccccagccga gttcgtaata
    19141 ggcccatgcg gaaccgagca caatgccgag cgtcaggaag atccacgcag ccagcgtcca
    19201 cggacgagta aaacgcgcat aagtgctgtc cagacgccca ctcaacaaag atgcaatggc
    19261 aaaagcaaac gccaccgaga aaccgacgta ccccatatag agcagaggcg ggtggaaaat
    19321 cagccccgga tcctgcaaca acgggttaag atcgcgccct tcaatcggga aattcggcag
    19381 cgtgcgtgag aacgggttag aggtaaagag aatgaacagc aaaaagccga cactgaccat
    19441 ccccattatc gccagtacgc gggcaacaat atccagcgga atacgctgac taaaaatcgc
    19501 taccgcaaag gtccagccgc tcatcagtag cacccacagc aggagcgagc cttcatgcgc
    19561 gccccaggta gccgccacgc gataccacac cggaagctgg gtattggagt tgctggcaac
    19621 ataggtgacg gtaaagtcgt tgaccacgaa agcattgacc agcaccagaa atgcgccagc
    19681 cacagacata aacagcagcc aggcaaacaa gcgggaagac gccatcatgc gcgcgtcccc
    19741 gcgcgccacg ccccatagcg gatacacaga cagcagcagc gcaattccta gcgccagaca
    19801 cagcagcccg ttaccaattt ctggcatcat gatgctgggt ccttataaac actcgccggg
    19861 cgacggtggt tagcttccat cgctttctca acttctggcg gcgtgtagtt ttcatcgtgt
    19921 ttcgccagca cttctttcgc gaggatatga ttgccttttt ccagttcgcc ctgcaccaca
    19981 acgccctgcc cttcacggaa cagatccggc aaaatgcctt cgtaagagac atctactgaa
    20041 ccttcagcgt cgtaaatggt gaaagttact tttagcgaat tgggatcgcg ctgcacactc
    20101 cccggcatca ccatcccgcc aacgcgcaga cgctgaccga cttccggcat ctgctgagtt
    20161 tcacgcttgc cgtagagaat ctcccccggc gtataaaaga gatcgatatt cgagcgcagc
    20221 gcatatagca ccagaccgat agtcagcgcc agccccgcca gcacggcaca ggcaatccac
    20281 aagcggtttt tacggcgaat attcatgcag cctcctgctg ttgcgcagca cgtaaacgcg
    20341 cctcacgcgc ccgctgttgc gccacgccac gcagaattgc gcgatgttgc atcaccgagt
    20401 gcacgactaa aaccaccagc ggaataacgg tcatcaccac cgccagccag acaaaaaagg
    20461 cgtaaccgcc cattgcgaaa aattcattcc aggaagcaaa tgcaggggtc atttacggcc
    20521 tcttttcagt atcagttcac tcacccacgg acggcgtttt tccatcagca aaatcaaatt
    20581 acgcatccgc atcagcgtca gcgtggcaga caggagcagg aagcccaaaa tcgaccagcg
    20641 cagcggcgaa cgcatcgccg gatcgatact ttgctgcatt cgcgttgatc cctgatgcag
    20701 ggtgttccac cactctacgg agtaatgaat aatcggcaga ttcaccacgc caatcagcac
    20761 caggatacct gccgcacgcc cagccagacg acggtcgtcg aaggcgtgcc acagggcaat
    20821 gacaccaaca tacagaaaca gcagcaccag ttcagaagtc agacgtgcat cccataccca
    20881 ccaggtgccc cacatcggtt ttccccatgc agagccggta accagggcaa taaaggtaaa
    20941 cacggcacca atgggggcca tcgccgccac cgccaggttg gccattttca tctgccagac
    21001 aaggccaata aacgccgcca ccgccattga tgcataaatg cccatcgacc agatcgccgc
    21061 aggcacatgc aggtagataa tgcggtagct atttccctgc tgataatcag ccggagcaaa
    21121 gccgaacccc cagatccagc cgacggtaag cacgaccaca ctggcaattg ccagccacgg
    21181 tataaaccag ccacagattt gatacagccg tggtgggatc gccagttgat gcagtgtttt
    21241 ccacatagtt tcgataccag actcgaacaa aaatcagtaa tccagcgtta ttgaatgctg
    21301 attcgtaacg ctgccgccgt cgcaaaagga cttaatgtcg cggtgcctgc cagcaacgcg
    21361 cctaaaattg ccagataccc atcaacgggc aaatgcatag aagccgcgtc catcgcggcg
    21421 gtggcaaaga tgagtaatgg gatagtcagc ggtaacacca gtatgctgag cagcacacca
    21481 ccgcgcttaa gtcccactgt cagcgccacg cccggcgcac caagaaagcc aagcgtaggg
    21541 gttcccagca gtagcgttaa cgccatcact tgccagccat aaacatccat tcccagtagc
    21601 attgctacca ggggcgaaag gatgagtaac ggcagaccgg ttaccatcca gtgcgccatc
    21661 accttcgcca gcacaacggc gggcaagggt aacggcaaca acatcaattg ttcaagactg
    21721 ccgtcctgca aatcgtcacg gaacagtcgc tcgagtgcca gcaaggatga aagcagcgcg
    21781 gcaacccaga taatacccgg cgcaatacgc gccagcagtt gcggctccgg accgatactg
    21841 agcggaaaaa gggtaatgac aatcaggaag aaccacagcg ggttggcgat ttcggcgctg
    21901 tggcgaaacg ctacgcgcag ctcaagacgg aaaatgcgcc agaacatcat gcggccctcg
    21961 tttgcgtcag tgaaatgcgg cgaattttac tttcagcaac gttgagcggc tggtgggtag
    22021 tcagaatcac aatccccccc tgctccgtat gctgcgccat acgctgggtc agacgatcga
    22081 cgccattaac gtcaatcgcg gtaaaaggct cgtcgaggat ccataacgtg gcacgggtca
    22141 gccacagacg cgctaaagcg acgcggcgtt gttgcccggc agaaagttga tttaccggaa
    22201 tatcttcgaa tccggcaagc ccggcctgcg ccagggcttc cagacattgt gcggtatcgc
    22261 catcgcgatg ataaaagtgc agattttcta acgccgtcag ccgggttttg atccccggct
    22321 gatggcctat ccataacagg ttttgatggt agctgtcgcg tacctgatgc aagggctgcc
    22381 cttgccagag aacctcgcct gcatcagggc gagacaaccc cgtcagcaaa cggagaagcg
    22441 ttgtcttccc cgcgccgttg ctaccggtga tttgtaccca ctctcctgcg ttcagcgtaa
    22501 atgataaacc actaaataag gttcgttcat cccgctcgca aagtaactct ctggcttcaa
    22561 gcatactcac gcaataaccc tgttaaaaac ctggctcgac ttcacgcatg tcgggcagct
    22621 tgtgcgctat ccctttatgg caatcaatac aggtttgccc atctttcacc gcctggtcat
    22681 gcatcttcgc ggcaaccgat ttctgggcgg ttgtatccat atactcgaag ttgtgacagt
    22741 tacggcactc ctgcgagttg ttgtccttca tgcgccgcca ctcattctgt gccatcgtca
    22801 ggcgatgagc ttcaaatttc tgcggcgtgt caataacgcc aaaaatttta ccatacagct
    22861 ctttacttgc tttgagcttg cgtatcatct ttggcacaaa ctcgtgcgga acgtgacaat
    22921 ccggacaggt cgcacggacg ccgctacggt tgttgtagtg cacggaatcc atgtattcct
    22981 gatacaccgt gttacgcatt tcgtggcagc taatgcagaa ctcttcggta ttggcttttt
    23041 ccatcccggt gttaaagccg ccccagaaga cgatgccacc gacaaaaccg atcaacagca
    23101 gcgtccccag cgccagacgg ctgggggtac gccaccattt ccacaggcgc ttaatcagac
    23161 caggcttacg gtcagaattt cccataataa cctcttattt cccgtaacct tttgacgggg
    23221 taaaggtatt ccccacgatt ggcgcggtat cggcctgcgg tacgtgacat tgcagacaga
    23281 aataacgacg cggagccact tccgcgccca ctttgccgtc gctgtccata aagtgagtag
    23341 gactaatgcg cggcgcgcca gtggtgcgat aactttcgac accgtggcac tgcaagcagc
    23401 ggttggtatt ggtcgttacc tgataacctt caacgctatg cgggatcatt ggcggctgat
    23461 tcacatagtt cagcggcatc cgatcctgct cttttggcat ccgaatggcc ccttcctgcg
    23521 tcccggatac ttccggcgac tggctaaaat cgacgccatt agccgcccaa accgcgccgc
    23581 ttaccaccag ggccagcatc gccgtccatt gacacagcgc tttcttcagg tcatggcttt
    23641 tcatgatttc gctcccgaac tccatcgtgt agttattgta aatacatcct cagaacagac
    23701 atccacgcag cgaccgcacg tcatgcaatc gcggctggtg acctgcaccg ggctttgttc
    23761 atccagcacc ggggcacgta gcacatgcgg ttccgggcaa acatgaaaac aatccataca
    23821 gcggttacat ttctgccgat cggtggccgc aacggtaatc acacctttgc tacccagcac
    23881 gccatacagt gcaccaaccg gacaaatgtg cccgcaccag ccgtgttcaa cgaccagtag
    23941 atcaaataaa aacagcgcga gaataagcag cgcgccgctg ccgaagccca ttaccaggct
    24001 acgccccatc agggaaacgg ggttgatcca ttcccagatg agcgtgccag ttaaggccga
    24061 tcccaccaga atgatcacca acagcacgta gcgaatgtgg cgagggatcg tcgcagactg
    24121 attgaggtca aatcgtctgc gtaaccaatt tgctaagtcg gtaatcgggt tcagcgggca
    24181 gacccagctg caaaataatc gctttcctgc cagggcgtag agcacggtga taatcaccgc
    24241 accagtcagc gctaccgtgg caggcagatg accgctggca agactttgca gtgtcatcag
    24301 cggatcggtc agtggaacgg tgtcgaataa caggctactg ctgtagttgc cgtgcaagat
    24361 ccacacacca aaccacggac cgctcaaaaa catccccagc acgaagaact gacaaaggcg
    24421 acgtaacact aaccaacggt gactgcgcca ccagcctttt ttctccagcg cctcgcgccc
    24481 ggcgtcacgt ttacgatttg ccattgttcc cctccagcca gccgaagcgg taatggtgac
    24541 ctaactcccc tttcgccagt gacagcggta acaccttgat tgccggttgt tccagcacgc
    24601 acactttttc gcacttaccg cagccggtac aggcgtcgct gtgaaccgtc ggcagaaagc
    24661 gggcgtgctt accggttcgc gtgttgcgct ccagctccag ggtgatggcc tcatcaattt
    24721 tcgggcattc gcgataacaa acatcgcagc gcagcccctg aaagttgaga cagttttcct
    24781 ggtccaccag taccgccagc cccatccgcg cgtcgtcgat cgattcgatc tcacgatcca
    24841 gcgcaccgct cgggcacact ttggcgcacg gaatgtcctc acacatttcg caaggaatat
    24901 cccgtgcgac aaaatatggc gtgcccgccg acagaccaga ggccagcgtc gccagtttta
    24961 aggtgtcgta agggcaagcc tgaacacact gaccgcaacg cacacaggca ctggcaaagg
    25021 cgttctcgtt tatggctccg ggcgggcgca accgcacacc agatgcgcgt gcggtttgct
    25081 gttgtaaccc cagcgccaca cccacggcag ccagcccgcc tgctgtgcga acgacatcgc
    25141 gcagaaagcg gcggcgacca ttttgaggtt tcgctgaccg ggacataatg gcttacacct
    25201 tctccagttt gaccgcgcac ttcttgaagt ccgtctcttt cgagagcgga tcggtcgcat
    25261 ccagcgtcag tttgttaacc agctgtgcgg cgtcgaagaa cggcatgtac accaggccct
    25321 gcggcggacg gttacgaccg cgcgtttcga caatcgagat cacttcgcca cggcgagaaa
    25381 ccactttcac tttgtcgcca cggcgcagat cgcgcgcttt cgcatccagc gggtgaataa
    25441 acagaaccgc ttccgggaag gcgcggtgca gttccggtac acggcgagtc atactgccgg
    25501 tatgccagtg ctccaggacg cgtccggtag agagccacag gtcgtactct tcatccggcg
    25561 cttccgccgc aggttcgaac ggcagcgcga agatcaccgc tttgccatcc ggtttaccgt
    25621 agaacttgta gccttcgccc gctttcacgt acgggtcgtt accttcgctg taacgccact
    25681 gcgtttcttt accgttcacc accggccagc gcagaccgcg tgctttgtgg taatcatcga
    25741 acggcgcgag atcgtgaccg tgaccgcgac caaaccatgc gtactcttcg aacaaccctt
    25801 tttgcagata gaagcccagc tcgcgagatt cgtcgttcag ctgatcttcc gccagttcgg
    25861 ataccgggaa tttgctcact tccggagtgg catacagaac ctcatacagc gttttgccac
    25921 gcagttccgg tttcttagcc agcagctctt ccggccacac ttcttcagtt ttgaagcgac
    25981 gggagaactg aactaactgc cagagatccg attttgcttc acccggtgcc tgtacctgct
    26041 gacgccagaa ctgagtacgg cgttcggcat taccgtaagc cccctctttc tctacccaca
    26101 ttgcggtcgg caggatcaag tccgctgcca gcgcactgac cgtcggatat ggatcggaaa
    26161 cgatgataaa gttgcgcgga tcgcgccagc ccggcatacg ctcttcatta atgttcggtc
    26221 cggcctgcat gttattggta cacatggtcc agtaaacatt cagtttgccg tctttcagcg
    26281 cacggtcttg tgccaccgcg tgcagaccga ttttcgccgg aatggtgcca ctcgggatat
    26341 tccacttctt ctcgcaaata tcacgatgtt tctcgttagt caccaccatg tccgcaggca
    26401 gacggtgagc aaaggtgccc acttcacgcg cagtaccaca cgcggaaggc tgcccggtca
    26461 gggagaacgg accgcaaccc ggctgggaaa ttttgccggt cagcaggtgc aggttgtaga
    26521 ccaggttgtt ggcccacaca ccacgggtat gctggttgaa gcccatcgtc cagtaggaga
    26581 tgactttctt gttcggatcg gcatacagct gcgccagttg ttctaactgg tctttcggca
    26641 cgccggtcat ttcggcggtt ttttccagcg tatattcagc aacgaaggct ttgtaatctt
    26701 caaagctcat cggttcggag gcgtcagaac ccggattctt cgctgctttt tccagcggat
    26761 gggtcggacg taaaccgtag ccgatgtccg tcgccccttt gcgcaggtta acgtgtttgc
    26821 tgaagaagtc ctgatttatc gcattgtttt gaatgatata gttggcgata tagttcagga
    26881 tcaccaggtc agattgcggc gtaaagatga tgccgttatc cgccagctcg aagctacgat
    26941 gctggtaggt agaaagcacc gccacggtaa cgttctggtt agagagacga cggttagtga
    27001 tgcgcgacca gaggatcggg tgcatctccg ccatgtttgc gccccacagc acaaacgcgt
    27061 cagcctgctc gatgtcgtca tagcagccca tcggctcatc cataccaaag gtacgcataa
    27121 agccaactac tgccgacgcc atacagtgac gcgcgttcgg gtcgatgttg ttcgaacgga
    27181 agcccgcttt aaacagcttg gacgcggcat aaccttccca gatagtccac tgaccagaac
    27241 cgaacatacc gatcgattcc ggcccttttt ctttcagggc ggttttgaat ttctcttcca
    27301 tcacatcgaa ggcctgatcc caggtgattg gggtaaattc gccttcttta tcatatttac
    27361 cgtttttcat acgcagcagc ggctgcgtca aacggtcttt accgtacatg attttgggca
    27421 ggaaatagcc cttaatgcag ttcaggccac ggttaaccgg tgcgtccggg tcgccctgac
    27481 aagccaccac acgcccctgc tgcgttccga ccagaacgcc gcaacccgta ccgcagaaac
    27541 ggcacggcgc tttatcccat ttaatggctt cctgctgacc aacaacggcg cgggcaacgc
    27601 ccggcacgct gagaccggca gccgccgcag cggccgcaac ggcgttagct ttcataaagc
    27661 tacgacgact gagtttcatg gtgtttcctc accttgctct tcctgctggt gataaaccag
    27721 cgacaccgcc agcacgccct ctacgttgcg tactgactca atggtttgga tcagcgtttc
    27781 gctgtcttct gcttccacca ccacaatcaa ctgaccgctc ggcgcgtcgc tgacagcaac
    27841 ttcacagccg gtaaaggcgt tcagttgggt gctgatgtct gaaattcgtt cgcttttggc
    27901 ctgcacgacc aggctgcaaa cttgccagtt agtgtgcatg gagatactcc gcagttatgg
    27961 ctgataccgg acagctggct gcacatgctc cacatccgtt gcaaagttgg ctattaagtt
    28021 gcggctggta gatcccggag agcgtcgggc gaaagataat tgccattggc tcacagctat
    28081 cctgacagcg gcggcattca actgactgat acgccaggca cgcgtcccca atggtgaact
    28141 gcaaatccca ggccctggtg tggcgcggag aaaatagcga ttcggggcaa gcctgcgcgc
    28201 aggcgtaaca gaagctgcac tcgttatttt tgaaattaac gctcggatag ctacccgcgc
    28261 cgcgttgcag aatgttgttt tcacaagcat taatacaggc gtcgcagcgg gtgcaatggg
    28321 tcagaaaatg agattcatca ccggaccagg gcggacggat accgttactg gctttgcgcc
    28381 agcgaccagt gagtatgccc cgacgggatg catcaatctt cacattgacc ttccatcatt
    28441 aacgcgctct gaaaattgag agcgaccaaa taaaccgcat aattaataag ccatttttat
    28501 agccgctaag atattaaagg atgtgtcaaa gatgcatacc ccgatcgggg taaaacctgt
    28561 agcaggatca aaagagtggc gggaagcgtg gcaaaaacgg gcttttgctc aca
//
LOCUS       DAPOXO010000068        28249 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPOXO010000068 DAPOXO010000000
VERSION     DAPOXO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28249
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.068"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..299)
                     /gene="tuf"
                     /locus_tag="ROH59_003444"
     CDS             complement(<1..299)
                     /gene="tuf"
                     /locus_tag="ROH59_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDX4805885.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQM"
     gene            complement(370..2484)
                     /gene="fusA"
                     /locus_tag="ROH59_003445"
     CDS             complement(370..2484)
                     /gene="fusA"
                     /locus_tag="ROH59_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDX4805886.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2581..3051)
                     /gene="rpsG"
                     /locus_tag="ROH59_003446"
     CDS             complement(2581..3051)
                     /gene="rpsG"
                     /locus_tag="ROH59_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDX4805887.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="ROH59_003447"
     CDS             complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="ROH59_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDX4805888.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="ROH59_003448"
     CDS             complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="ROH59_003448"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HDX4805889.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYL
                     ESLRNAPIKVYALNEDLIARGLTGRISNDIIPIDYTDFVRLTVKHSSQMAW"
     gene            complement(3942..4301)
                     /gene="tusC"
                     /locus_tag="ROH59_003449"
     CDS             complement(3942..4301)
                     /gene="tusC"
                     /locus_tag="ROH59_003449"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HDX4805890.1"
                     /translation="MKRIAFVFSTAPHGTTAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWICAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4301..4687)
                     /gene="tusD"
                     /locus_tag="ROH59_003450"
     CDS             complement(4301..4687)
                     /gene="tusD"
                     /locus_tag="ROH59_003450"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HDX4805891.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSSVFFYREGV
                     YNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSN
                     LQPGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4687..5409)
                     /locus_tag="ROH59_003451"
     CDS             complement(4687..5409)
                     /locus_tag="ROH59_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX4805892.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5576..6388)
                     /gene="fkpA"
                     /locus_tag="ROH59_003452"
     CDS             complement(5576..6388)
                     /gene="fkpA"
                     /locus_tag="ROH59_003452"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDX4805893.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATTADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6609..6827
                     /locus_tag="ROH59_003453"
     CDS             6609..6827
                     /locus_tag="ROH59_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HDX4805894.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6876..7466)
                     /gene="slyD"
                     /locus_tag="ROH59_003454"
     CDS             complement(6876..7466)
                     /gene="slyD"
                     /locus_tag="ROH59_003454"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDX4805895.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7561..7761)
                     /locus_tag="ROH59_003455"
     CDS             complement(7561..7761)
                     /locus_tag="ROH59_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HDX4805896.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7771..9504)
                     /gene="kefB"
                     /locus_tag="ROH59_003456"
     CDS             complement(7771..9504)
                     /gene="kefB"
                     /locus_tag="ROH59_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HDX4805897.1"
                     /translation="MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALL
                     AGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALG
                     TFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVV
                     LVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSSASSQRLFQGDQMALL
                     LVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIG
                     RLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNE
                     PEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLV
                     TLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQE
                     RRQLDGWDEFE"
     gene            complement(9504..10055)
                     /gene="kefG"
                     /locus_tag="ROH59_003457"
     CDS             complement(9504..10055)
                     /gene="kefG"
                     /locus_tag="ROH59_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HDX4805898.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10186..12099
                     /locus_tag="ROH59_003458"
     CDS             10186..12099
                     /locus_tag="ROH59_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4805899.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGQAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADE
                     SPIQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEPF
                     DGDLEDYQQWLSDVQKQENQADEAPKENANSAQARKDQKRREAELRAQTQPLRKEIAR
                     LEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQ
                     EQLEQMLLEGQSN"
     gene            12099..13121
                     /locus_tag="ROH59_003459"
     CDS             12099..13121
                     /locus_tag="ROH59_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDX4805900.1"
                     /translation="MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFT
                     PHWHRLELPDGDFVDLAWSEDPAQARHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGNDLPIDAAVIVSAPFMLEACSYHMEKGFSRIYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            13115..13333
                     /locus_tag="ROH59_003460"
     CDS             13115..13333
                     /locus_tag="ROH59_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HDX4805901.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            13387..14256
                     /locus_tag="ROH59_003461"
     CDS             13387..14256
                     /locus_tag="ROH59_003461"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HDX4805902.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQSLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(14311..14715)
                     /locus_tag="ROH59_003462"
     CDS             complement(14311..14715)
                     /locus_tag="ROH59_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDX4805903.1"
                     /translation="MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            15017..15649
                     /gene="crp"
                     /locus_tag="ROH59_003463"
     CDS             15017..15649
                     /gene="crp"
                     /locus_tag="ROH59_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HDX4805904.1"
                     /translation="MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            15700..17790
                     /locus_tag="ROH59_003464"
     CDS             15700..17790
                     /locus_tag="ROH59_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDX4805905.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQVLLAKDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQDAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(17857..19077)
                     /gene="argD/dapC"
                     /locus_tag="ROH59_003465"
     CDS             complement(17857..19077)
                     /gene="argD/dapC"
                     /locus_tag="ROH59_003465"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HDX4805906.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQYKGRARDFLYAGAEEGVMVLNAGPDVMRFAPSLVVEDADIDEG
                     MHRFAHAVAKVVGA"
     gene            complement(19163..19726)
                     /gene="pabA"
                     /locus_tag="ROH59_003466"
     CDS             complement(19163..19726)
                     /gene="pabA"
                     /locus_tag="ROH59_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HDX4805907.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHNGVGVFKGLANPLTVTRYHSLVVEPDSLPECFEVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(19758..20360)
                     /locus_tag="ROH59_003467"
     CDS             complement(19758..20360)
                     /locus_tag="ROH59_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HDX4805908.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNKLNIRQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYLEKEGNAL
                     MQDLEEEKYLTSLEKDKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQNGAMGDLTALQMIFSKVVSEVGESE"
     gene            complement(20350..20517)
                     /locus_tag="ROH59_003468"
     CDS             complement(20350..20517)
                     /locus_tag="ROH59_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HDX4805909.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEALRRHYER"
     gene            complement(20622..21194)
                     /gene="ppiA"
                     /locus_tag="ROH59_003469"
                     /gene_synonym="rotA"
     CDS             complement(20622..21194)
                     /gene="ppiA"
                     /locus_tag="ROH59_003469"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HDX4805910.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            21465..22646
                     /gene="tsgA"
                     /locus_tag="ROH59_003470"
     CDS             21465..22646
                     /gene="tsgA"
                     /locus_tag="ROH59_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HDX4805911.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
     gene            22908..25451
                     /gene="nirB"
                     /locus_tag="ROH59_003471"
     CDS             22908..25451
                     /gene="nirB"
                     /locus_tag="ROH59_003471"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HDX4805912.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVVCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            25448..25774
                     /gene="nirD"
                     /locus_tag="ROH59_003472"
     CDS             25448..25774
                     /gene="nirD"
                     /locus_tag="ROH59_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HDX4805913.1"
                     /translation="MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYDARVKDG
                     VVQLRG"
     gene            25901..26707
                     /gene="nirC"
                     /locus_tag="ROH59_003473"
     CDS             25901..26707
                     /gene="nirC"
                     /locus_tag="ROH59_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HDX4805914.1"
                     /translation="MFTDTITKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGTISHGQMW
                     AILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
                     NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYT
                     LAGIGHNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            26726..28099
                     /gene="cobA"
                     /locus_tag="ROH59_003474"
     CDS             26726..28099
                     /gene="cobA"
                     /locus_tag="ROH59_003474"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDX4805915.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEYGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
BASE COUNT         6835 a         7552 c         7139 g         6723 t
ORIGIN      
        1 tccatctgag cagcaccggt gatcatgttt ttaacatagt cggcgtgccc cgggcagtct
       61 acgtgtgcgt agtgacgggt cggggtgtcg tattcaacgt gagaagtgtt gatggtgata
      121 ccacgagcct tttcttccgg cgcgttatcg atctggtcga atgcacgagc agcaccgccg
      181 taggttttag ccagtacggt ggtgattgca gcggtcagag tagttttacc gtggtcaacg
      241 tggccgatag taccaacgtt aacgtgcggt tttgtacgtt caaatttttc tttagacacg
      301 gctatattcc ttactatagt gctctcccct tcaggagaga gcacgggact ttggtattaa
      361 cccttaggct tatttaccac gggcttcaat tacggcctga gcaacgttac tcggcgcttc
      421 atcatacttc aggaattcca tagtgtatga tgcgcgacct ttggtcagag aacgcagctg
      481 agttgcatat ccgaacattt cagacagcgg tacttcagcg tggatcttaa cgccagtaac
      541 ttcagattcc tgacctttga gcataccacg acgacggctc aagtcaccga taacgtcacc
      601 ggtgttctct tcaggagttt ctacttcaac cttcatgatc ggctcaagca gaactggttt
      661 cgctttctta aagccttctt taaaggcgat agaagcagcc agtttaaacg ccagttcaga
      721 ggagtcaacg tcatggtaag aaccgaagtg cagacgaata cccatgtcta ctaccgggta
      781 gcctgccagc ggacctgctt tcagctgttc ctggatacct ttatcaacgg ccgggatgta
      841 ttcgccaggg attacaccac ctttaatgtc gttgatgaac tcgtagcctt tcgggtttga
      901 acccggctcc agcgggtaca tgtcgataac aacatgacca tactgaccac gaccaccaga
      961 ctgtttcgcg tgtttacctt caacatcggt aactttctgg cggatagttt cacggtaagc
     1021 aacctgcggt ttacctacgt tcgcttcaac gttgaattca cgcttcatac ggtcaacgat
     1081 gatgtcgagg tgcagttcgc ccatacccgc gatgatggtc tggttagatt cttcgtcagt
     1141 ccatacacgg aaagacgggt cttctttagc cagacggccc agagccagac ccattttttc
     1201 ctggtcagct ttggttttcg gttcaactgc gatggagatt accggctcag ggaattccat
     1261 acgttccaga atgatcggcg catccgggtc acacagggtg tcaccagtgg ttacgtcttt
     1321 cagaccgatt gcagctgcga tgtcgcccgc gcgaacttct ttgatctctt cacgtttgtt
     1381 agcgtgcatc tgaacgatac gaccgaaacg ctcacgtgca gctttcacgg agttcagtac
     1441 ggtatcacca gagttaacca caccggagta cacacggaag aaggtcaggt taccaacaaa
     1501 cgggtcggta gcgattttga acgccagtgc agagaacggc tcgtcatcac ttgcgtgacg
     1561 ctcagccgga gtgtctttac cgtcgtccag gataccgttg atcgcaggta cgtcaaccgg
     1621 ggatggcagg taatcaatta ccgcatccag catcgcctga acacctttgt tcttgaacgc
     1681 agaaccacag gttaccagga tgatttcgtt gttcagaacg cgctgacgca gagcaccttt
     1741 gatttctgct tcagtcagtt cttcaccacc cagatatttt tccatcagct cttcagaagc
     1801 ttcagctgcg gattcgatca ggttctggtg ccattcgtta gccagttcaa ccatgtctgc
     1861 cgggatatct tcgtattcga aggttacgcc ctggtcagcg tcgttccagt tgatagcttt
     1921 cattttcacc aggtcaacaa caccggtgaa atgttcttca gcaccaatcg ccagctgcag
     1981 cggaaccggg ttcgcgccca gacgggtttt gatctggtta acaactttca ggaagttcgc
     2041 acccatgcgg tccattttgt taacgaacgc aatacgcgga actttatatt tgtttgcctg
     2101 acgccatacg gtttcagact gcggctgaac accaccaact gcgcagtaaa ccattaccgc
     2161 accatcgaga acacgcatgg aacgttctac ttcgattgtg aagtcaacgt gccccggggt
     2221 gtcgatgatg ttgatgcgat gcggctcata ctgcttagcc ataccagacc agaatgcagt
     2281 agtcgcagcg gaagtgatgg taataccacg ttcctgctcc tgctccatcc agtccatggt
     2341 tgcagcgccg tcatgaactt caccgatttt atggtttaca ccggtgtaga acagaatacg
     2401 ttcggtagta gtggttttac cggcgtcgat gtgcgcactg ataccgatgt tacggtagcg
     2461 tgcgatgggt gttgtacgag ccatttgttt cctcgtttat cttttaggcg ttcaatttaa
     2521 gtagcccaaa gcgggctgct tactggaagc gcccgcctgg tgactaaaac tccgaaggga
     2581 ttaccaacgg tagtgtgcga acgccttgtt ggcttcggcc atacggtgaa cgtcttcacg
     2641 tttcttaact gcagtacctt tgttttctgc agcatcagaa agttcgttcg ccaggcgcag
     2701 agccatggat ttatcaccgc gtttacgagc agcttcaacg atccaacgca ttgccagagc
     2761 attacgacga accggacgga cttcaactgg tacctgataa gtagaaccac caacgcggcg
     2821 agacttaact tctacagtcg ggcgcacgtt ttcgagagct acttcgaatg cttccagttc
     2881 agatttacca gagcgctgag ccagggtctc cagcgcgctg tatacgatag attcagcagt
     2941 agatttttta ccatctacca tcaggatatt tacaaattta gccagcagtt ctgatccgaa
     3001 cttcggatcc ggcagaattt tacgctgacc aatgacgcga cgacgtggca tggaaatact
     3061 ccgttgttaa ttcaggattg tccaaaactc tacgagttta gtttgacatt taagttaaaa
     3121 cgtttggcct tacttaacgg agaaccatta agccttagga cgcttcacgc catacttgga
     3181 acgagcctgc ttacggtctt taacaccgga gcagtcaagc gcaccacgta cggtgtggta
     3241 acgaacaccc gggaggtctt taacacgacc gccacggatc aggatcacgg agtgctcctg
     3301 caagttgtga ccttcaccac cgatgtagga agtcacttcg aaaccgttag tcagacgaac
     3361 acggcatact ttacgcagcg cggagttcgg ttttttagga gtggtagtat atacacgagt
     3421 acatacgcca cgtttttgcg ggcatgcttc cagcgcaggc acgttgcttt tcgcaacttt
     3481 gcgagcacgt ggtttgcgta ccagctggtt aactgttgcc attaaatagc tcctggtttt
     3541 agcttttgct tcgtaaacac gtaataaaac gtcctcacac aatatgagga cgccgaattt
     3601 tagggcgatg ccgaaaaggt gtcaagaaat atacaacgat cccgccatca ccaggccatc
     3661 tggctggagt gcttaaccgt aagtctgacg aaatcagtat agtcaatggg aatgatgtcg
     3721 ttcgaaattc gaccagtcaa accgcgggca ataaggtctt cgttcagagc atagacctta
     3781 atgggggcat tacgcagact ttcaaggtag cggttgccgt caactgcggc agttacgcca
     3841 tcttgcaata atagcagttc gtcaccttca ctgagcagac gcagcagcgc agcaaagtcc
     3901 gtcagccagg gtgaacgatg taatgtgtgc agcataacgc ctcaaaacct caaaataaca
     3961 tcgtagttgg cgagttcgcg gcgtaaggca tctgcttcga gcggcgtggc ttcgaccaca
     4021 aagggtgtct gcggatctaa cccacgttcg cgcagtgaag ccgcgcaaat ccagcactgt
     4081 tcaatatcgt acagacccaa caatttaaaa gtggcaatgt aatcacgcgc cagcactgca
     4141 tcgggctttt gtcctggcag cagctgaaaa acgccatcag caataaagaa gacggccaga
     4201 tcgtcagtta atgcggaagt tgccagtaaa gcatctaaac cttcccggcc tgcagttgta
     4261 ccatgaggcg cagtagaaaa aacaaacgca attcgtttca tcagaactgt accaccctgt
     4321 cacaggtcag cgaggcttcc gccagcgcgc caagtccgct taaggtaaat cccggctgaa
     4381 ggtttgacga agcaagcccc agtcttccgg cctccgtttc atcaacaacg ccacggcgta
     4441 atgctgccgc tacgcagata ttcagcgcca caccatgttg cgcattcaac tgttgccagc
     4501 cgcgcacaag gtcaaattcg tcgcttgccg gtgaggtcaa ttggttagcg ttatagaccc
     4561 cttcccgata gaaaaaaacg ctgcttaact catggccttc tgctatcagc gcctgcgcaa
     4621 actgaaaagc actactcgcc tgttgcgtac cgtatgctgg cccggtcacc acgatggcaa
     4681 aacgcattac ttatcttgcc cctggaaatc accgctcttg aactggcgga tgtagagata
     4741 gacagtgtgt ttggagatgt tcaggcggtc agcaacctgg ttgatcgcgt ctttaatatc
     4801 gaagatccct ttctcgtaga gatttagcac gatctgacga tttttggcgt tattagaaac
     4861 attgcgatcg gcattcactt cttcgatggt gaactccagc gtttgggtaa ccagatcttc
     4921 aacagaagag gcaaagttga cgcttgaacc gacatccgga gtttccggcg gcacaaaagt
     4981 gctcataatc tgcgagaagg gaacatcaag attcatattg atgcacagca gaccaattac
     5041 acgctgttcg cggttacgaa tcgcgatagt cagggacttc attaatacgc cgcttttggc
     5101 gcgagtaaag tagcatttag aaacgctgct atccgctccc gtcatatcgt gcagcatacg
     5161 tagcgccagg tcagtaattg gcgaaccaat cttccggcct gtatgttcac cgttagcaat
     5221 gcgaatggct gaacatttta gatcctgcaa agagtgcaaa acgatttcac agtgggagcc
     5281 aataagcatc gctaacccgt ccaccaccgc ttcgtaggat ttcagaatat caaaatcggt
     5341 ctggtcaaaa ggacgttgat ccagtaaatc caactcactg gtttcgttgg ttaaaagcga
     5401 cctggacatg aaaaaaaaca ctccttttca ggagcctgtc gttaactttt cagggcaggc
     5461 tcattaatga tgcgggtaac taaattaata cagcggaggt tccgctttcc agcactaatt
     5521 atatccggcc tgtaataaaa aaaccgccgc ctggtcaggc ggcggttctt aatgcttatt
     5581 ttttagcaga gtctgcggct ttcgcatcag cttccggctt tgcatcagcc ttcggcgctg
     5641 gtttcacatc cagcagctct acgtcaaaca ccagggtaga attcggtggg atccccggaa
     5701 cacccgcttt gccgtaagcc agttctggtg gaataaccag tttgatctta ccgcctttct
     5761 tgatgttctt cagaccttct gtccaacccg gaataacacc gtccagacgg aaagagagcg
     5821 gttcaccacg ggtgtaagag ttgtcgaact ctttaccgtc gatcagcgta cctttgtagt
     5881 tcactacaac agtatcgctg tctttcggtg cttcgccttt accggcttct actacctgat
     5941 aaaccagacc agtggaagag gttttcacac ctttctcttt ggcaaatttc tcgcggtact
     6001 ctttaccttt tgcttcgtta tcagccgcgt ctttttccat cttcgcctga gcagaagact
     6061 tcacgcgagc ttcgaatgct tgcagagtct gttcgatctc ttggtcggaa agtttgctct
     6121 tatcagcaaa tgcatcctga acaccagcga tcagctgatc tttatccagt ttgatgccca
     6181 gtttttcttg ttctttaaga gagttttcca tgtaacgacc cagcgaagca cccagtgcat
     6241 aagctgattt ctgatcgtca tttttgaacg ctgctttgct gtcagcagtt gtagcaggtt
     6301 ttgcagcttc agcagcaaaa gtgattggtg catgcagggc aacggccatt gtggtcgcca
     6361 gcagcgttac tttaaacagt gatttcatcc atatctccag gatcggggca tctcacccca
     6421 gggttaacta ttatcagaag ggtactataa agcgttgtcg aacaaatcta catacagaca
     6481 cgccctatta tcatctattt tcagactctt tttgtttaaa ttagtttcga tgaccgcgaa
     6541 atgagtgctg tctcgggcag caaagttaag tagaatccgc ggcgaccatt cgacaaaaga
     6601 ggtgaatcat gcaggattta tcattggaag cacgcctggc agagctggag agccgactgg
     6661 cttttcagga aatcaccatt gaagaactga acgtcacggt gaccgctcat gaaatggaga
     6721 tggcgaaact gcgcgatcat ctgcgtctgc tgaccgagaa gttaaaagcc agccagccgt
     6781 cgaacatcgc gtcgcaggct gaagaaacgc ctccgccaca ttattgaggc gtaaaaaaag
     6841 cgggaattcc ccgctttttt gtcacctttt cggtattagt ggcaaccgca accgccgttg
     6901 cctttaccgc cacagcagcc ttcgccaccg tgttcatgac cgtgatcgtg gccatgacca
     6961 ccgcagcaac cgtcgtggtc gtgatcgtgg tggtgatcgt gcgcgccgtg aacgtgacca
     7021 tgagccagtt cttcttcggt cgcttcgcga atcgccacaa cttcaacgtt gaatttcagg
     7081 ttctgaccag ccagcatgtg gttaccatca accactacgt gatcgtcttc aaccgcagtg
     7141 atttcaaccg gtaccggacc ctggtcggtt tcagccagga aacgcatacc tacctgcagt
     7201 tcatcaacgc ccataaatac gtctttagga acgcgctgca ccaggttttc gtcgtactga
     7261 ccgtaagcgt cattcgcgcc aacagcgaca tcaaatttgt cgccaacttc atgaccttcc
     7321 agcgccgttt ccaggccaga gatcagggaa ccgtgaccat gcaggtagtc cagcggcgca
     7381 ctcaccggag actcatcaac caacacaccg tcttctgtac gtacctgata ggccaggctg
     7441 accaccaggt cttttgctac tttcatgata tctcctgagc atgggaagaa tagtggcgca
     7501 gattgtagcg gaattctgca gccgtgtact cactagctta aaaaaactcg gcgcatatcg
     7561 ctagtccgga tgaaaaatcc cgatcacttg ctcatctttg cgaacgtgat cgcgggcttc
     7621 tttgtctgct tctcgcatct gatgtccaca cttaacacat tcaacgatat caatattatt
     7681 ttcgcgccac atcgccattg aatcctgagc ctgacaggcc gggcattttg cgcccgcaat
     7741 aaaacgtttt cggattgcca tctttaccct ctactcaaat tcatcccagc cgtccagctg
     7801 gcgtcgttct tgttgcattt cacgctggaa aatctcttcc agttcgcgtc gggcttccct
     7861 ggcgcgagaa atttgtacgg tatcagcatg catcgggatt aactcccgca gcattcgcat
     7921 atccaggcgg cgaaaatgca gttgcgcgcg ctgcgcctga tgcggatgca tgccaagcgt
     7981 gaccagcgtc ttgcgcccca gctctaacgc actggagaat gtttcacggg aaaactgcgt
     8041 cacccctgcc tgtaataact catgcgcttc cacacgtccg cgcgctcgcg caagaatatg
     8101 caaatgcgga aagtgctgct ggcatatttc caccagcttc atagtgtctt ccggctcgtt
     8161 acaggtaatg acgatagact cagcggcctc tgcacccgca gaacgtaaaa gatctacctg
     8221 cgtggcgtcg ccgtaataaa ctttgtagcc atatttgcgc atcaggttaa cggcactgat
     8281 atcccgctcc agtacagtaa tgcgcatttt atttgccatc agcaaacgac caatcacctg
     8341 accaaaacgc ccaaagccca cgacaataac ctgcggttta tcatcgttga cccatggttt
     8401 ttcgtcttct tcttccggtc cgttaaactg gcgggatagc catttatcta ccagcttcat
     8461 cagcagcggc gtggtcatca tggaaagcgt caccgtcacc agcaacagcg ccatctggtc
     8521 gccctggaat aagcgttgtg aagaagcgga agaaaagagg acaaaggcaa actcaccgcc
     8581 ctgactcaac acgccagcaa actgcatccg ctctgagcta cgcacgccat acaatcgcgc
     8641 cagcagatac agcacgagaa ttttcaccgc caccagcaca accacactta tcactaccca
     8701 caacagatgg gtataaagca ccccgaggtt gagtgacatg ccgacagaga taaagaacaa
     8761 accgagcagc aagcctttga agggatcgat agccgtttcc agttcatggc gatattcact
     8821 ttccgccagt agcacacccg caataaacgt accgagcgcc atcgacaacc ccagcgcatc
     8881 cataaacaat gcggaaccca acaccagcag cagcgtcgcg gcggtgaaca cttcccgcac
     8941 accagaagct gcaataaaac ggaataccgg acgcagtaaa tagcgcccgc caatcagcat
     9001 gccgacaaac gccagtgccg ggatcaccgc cagatcctga aacagcagta ccgagaaacc
     9061 taactggccg gattcgctgc gattcatccc tttttcacgc atcaactgca atgccattgc
     9121 ggttgaagac atcgcaaggc caatgccacc gaccaccgcc gcctgccagg cgaaatccgt
     9181 cagcatcaat aatcccgcca gcaacgccgc gcttaacagc acctgtgccg cgcctacgcc
     9241 aaaaatcgaa cgccgcagtt gccaaagctt ggagggattc aactcaaggc cgatgataaa
     9301 catcaggaat accacgccga gttccgaaaa gtggaggatc tcatcgacgt cgctaataaa
     9361 ccccagcccc cacgggccaa tcgcaatccc cgccagcaaa tatcccaaca ctgcaccaat
     9421 acccagccgc gatgccagcg gcaccgcagc caccgccgcg aagagaaaca gcactcctgc
     9481 gagtaaaaaa tcagaacctt ccatcagcgg cctcctggag acaacggatt tgccagccag
     9541 tcaccgtagg ctctggcgtg gctcgccagc tcctgtgcgc tttgccgtct cgcccagtaa
     9601 ataatgatgg ggcttaacca atgcatccgg cacatgcccg ccgccagttc aaaggggcgc
     9661 agaacatcgc tcatcggata gcgattcaac gcgtcataac ggtaagcact ttccggctcc
     9721 ccggtggtaa tcacgctacg ccagtacttt cccgccagtt ggtttccccc cggtccgctg
     9781 gcaaaaccac ggcttaatac ccggtccagc cactctttca gtagcgccgg gcagctatag
     9841 gtataaagag gatgctgaaa gacaatcacc tcgtgctcgc gcagtaatgc ctgctcacga
     9901 gggatatcaa taaaaaagtc gggatagtgc gcgtaaaggt cgtgcacggt aacattgctg
     9961 agctgcgtgg ccggtttaag cagaacccgg tttgccaccg agtcctgaga ttccggatgg
    10021 gcatacagca gcaaaacttt cgctggctga gacatcatcc ccctcccggt atggtttttg
    10081 tgtatagtcg ctgttttggg ctaccattgc gcccggtgcg gcagctcgcc catacattac
    10141 attatcataa tgataagtta acatagtctg aacatacggc gccttatgat tgttttttcc
    10201 tcgttacaaa ttcgtcgcgg cgtgcgcgtc ctgctggata atgccaccgc caccatcaac
    10261 cctgggcaga aagtcggcct ggtgggtaaa aacggctgtg gtaaatctac cctgctggca
    10321 ttgctgaaaa atgaaatcag cgccgacggc ggcagctaca cctttccggg aagctggcaa
    10381 ctggcgtggg tgaatcagga aacaccggcg ttaccgcaag cggcgctgga atatgtcatt
    10441 gacggcgacc gtgaatatcg tcaactggaa gcgcagctac acgacgccaa cgaacgtaac
    10501 gacgggcaag ccattgcaac cattcatggc aagctggatg ctattgacgc atggagtatt
    10561 cgctcccgtg ccgccagcct gctgcacggc ctcggtttca gcaatgaaca actggagcgc
    10621 ccggtaagtg atttctccgg tggctggcgt atgcgtctta accttgccca ggcgctgatt
    10681 tgccgttcag acttgctgct gctcgacgaa ccgactaacc acctcgatct cgatgccgtt
    10741 atctggctgg aaaaatggct gaagagctat cagggcacgc tgatcctgat ctctcacgac
    10801 cgcgacttcc tcgatccgat cgttgataaa attattcata tcgaacaaca aagcatgttc
    10861 gagtacaccg gcaactacag ttcgtttgaa gtacagcgcg ccacccgtct ggcgcagcaa
    10921 caagcgatgt acgaaagcca gcaggaacgc gtagcgcatc tgcaaagtta tatcgaccgt
    10981 ttccgtgcca aagccaccaa agcgaagcag gcccagagcc gtattaagat gctggagcgt
    11041 atggagctga ttgccccggc gcacgtcgac aacccgttcc gctttagctt ccgcgcgccg
    11101 gaaagcctgc ctaatccgtt attaaagatg gaaaaagtca gcgcaggcta tggtgatcgc
    11161 attattctcg actcgattaa actgaatctg gtccccggct cgcgcattgg tctgctaggc
    11221 cgcaacggcg cgggtaaatc gacattaatc aaactgttag ccggtgaact tgcgccagtc
    11281 agcggtgaaa ttggtctggc gaaagggatc aagctcggct acttcgccca gcatcaactt
    11341 gaatacctgc gcgccgacga atcgcctatt caacatctgg cacgtttagc gccgcaggag
    11401 ctggaacaaa aactgcgtga ttacctcggc ggctttggtt tccagggcga taaagtaacc
    11461 gaagaaacgc gccgcttttc cggtggggaa aaagcccgcc tggtgctggc attaattgtc
    11521 tggcagcgtc cgaatctgct gctgctcgac gaaccgacta accaccttga cctcgacatg
    11581 cgtcaggcac tcactgaagc attaatcgag ttcgaaggcg cgctggttgt cgtctcgcac
    11641 gaccgtcatt tgctgcgttc caccactgac gatctctacc tggttcacga tcgtaaagtc
    11701 gaaccgttcg acggcgatct ggaagattat caacagtggt tgagcgacgt acaaaagcag
    11761 gaaaaccagg ccgacgaagc gccaaaagag aacgcgaaca gcgcccaggc acgtaaagat
    11821 cagaagcgtc gggaagcgga gctgcgtgcg caaacccagc cactgcgtaa agagattgcc
    11881 cgtctggaaa aagagatgga gaagctgaac gcgcaactgg cgcaggcgga agagaaactc
    11941 ggcgacagcg aactgtatga ccagagccgt aaagcggagt tgaccgcctg cctgcaacag
    12001 caagccagcg ccaaatccgg cctggaagag tgcgaaatgg cgtggctgga agcccaggag
    12061 cagcttgagc agatgctgct ggaaggccaa agcaactgat ggcgcagata acgacgaccg
    12121 atgccaatga atttagcagc agtgctgaat tcacccctat gcgcggcttt agcaattgtc
    12181 atctgcaaac catgctgccg cgtctgtttc gtcgcaaggt gaaattcacc ccgcactggc
    12241 atcgactgga gttgcccgac ggcgattttg tcgatctcgc atggagtgaa gatcctgcac
    12301 aggcgcggca taaaccgcgt ttagtggtat ttcacgggct ggaaggcagt ctcaatagcc
    12361 cttacgctca cggtctggtt gaggcggcgc aaaagcgcgg ctggctgggc gtggtgatgc
    12421 attttcgcgg atgcagcggt gaaccaaacc gtatgcaccg catttaccat tcgggcgaaa
    12481 ccgaagacgc cagttggttt ttacgctggc tgcaacgcga gtttggtcat gcgccaacgg
    12541 ctgccgtcgg ctattcgctc ggcggtaata tgctggcctg tttgctggca aaagaaggta
    12601 atgatctccc gattgatgcg gcggtgattg tctctgcgcc gtttatgctg gaggcctgta
    12661 gttaccatat ggaaaagggc ttttcccgca tttatcagcg ttacttgctg aacctgttaa
    12721 aagccaatgc cgcgcgcaag ctggcagcct accccggaac actgccgatt aatctcgcgc
    12781 agttaaaatc ggtacgtcgc atccgtgaat ttgacgatct catcaccgcc agaattcacg
    12841 gctacgctga cgctatcgac tattatcgtc agtgtagcgc catgccgatg ctcaatcgga
    12901 tagccaaacc gacactgatt attcacgcca aagacgatcc gtttatggat catcaggtga
    12961 tcccgaaacc ggaaagtctc cccccgcagg tggagtatca gctgactgaa catggcggtc
    13021 atgttggctt tattggcggt acattacttc atccgcaaat gtggctggag tcacgcattc
    13081 ctgactggtt aacaacgtat ctggaggcga aatcatgttg attccgtggc aagacctctc
    13141 ccccgaaacg ctggaaaatt taattgaaag ctttgtgtta cgtgaaggca ccgattatgg
    13201 tgaacatgag cgtacacttg aacagaaagt cgccgacgtc aaacgccagc tacagtgcgg
    13261 agaagcggtg ctggtatggt cggagctgca cgaaacggtc aatatcatgc cgcgcagtca
    13321 gtttcgcgaa taacctgcaa ccgtcggcgg acgagataat aatgatagct aagtcatgga
    13381 gttactatgt ctgccaaaca tccggtcatt gcggtaacag gatccagcgg cgcggggacc
    13441 accaccacca gcctcgcgtt tcgtaaaata ttcgcgcagt taaatctgca tgcagccgag
    13501 gtggaaggcg acagttttca ccgttatacc cgcccggaaa tggacatggc gatccgcaaa
    13561 gcgcgcgacg ccgggcggca tatcagctac ttcggccccg aagcgaacga cttcggcctt
    13621 ctggaacaaa ccttcattga atacggtcag agtggcaaag ggaaatctcg caaatatctg
    13681 catacctacg atgaagccgt accgtggaat caggtaccgg ggacattcac cccctggcaa
    13741 tctttaccgg aacccactga tgtactgttt tatgaaggtt tacacggcgg cgtagtcacg
    13801 ccacagcata acgttgcgca gcatgtggac ttactggtcg gcgtggtgcc tatcgttaac
    13861 cttgagtgga ttcaaaaact gatccgcgac accagcgagc gcgggcactc acgagaagca
    13921 gtgatggact cggtagtgcg ttcaatggaa gactatatca actacatcac accgcagttt
    13981 tcccgcaccc atcttaactt ccagcgcgtt cccaccgtcg acacctcaaa cccgttcgcg
    14041 gcaaaaggta tcccgtcact ggatgaaagc tttgtggtga tccattttcg taatctggaa
    14101 gggatcgatt tcccctggct gctggcgatg ttgcaaggct cattcatttc ccacatcaat
    14161 acgttagtgg tgcctggcgg caaaatgggt ctggcaatgg aattaattat gctgccgctg
    14221 gtgcaacgat tgatggaagg aaagaaaatc gagtaacgct gctattacgc cggataaaat
    14281 actatccggc ttcacaacgg gatagttaaa tcacgcggca accacttcat acgagtgagt
    14341 aatattcacc gctttttcca gcatcagcgc cactgagcaa tatttctcgg cagaaagatc
    14401 aaccgcacgc gcaaccgctg cgtctttcag atcgcgaccg gtgacgataa aatgtagatt
    14461 aatgtgcgta aacaggcgtg gtgcctcttc gcggcgctca gaggtcaatt ttacttcaca
    14521 atcgaccaca tcctgacgcc ctttttgcag gatagaaacc acatcgatgg cactgcaacc
    14581 acccgccgcc atcaacacca tttccatcgg gcttggtgct ttatcgcctg agttgccgtc
    14641 cattaaaatc tggtgaccag aggcggattc gcccagaaaa gttaaccctt cgacccactt
    14701 cactcgcgct tgcatttttg ctactccact gcgtcaattt tcctgacaga gtacgcgtac
    14761 taaccaaatc gcgcaacgga aggcgacctg ggtcatgctg aagcgagaca ccaggagaca
    14821 caaagcgaaa gctatgctaa aacagtcagg atgctacagt aatatattga tgtactgcat
    14881 gtatgcaaag gacgccacat taccgtgcag tacagttgat agccccttcc caggtagcgg
    14941 gaagcatatt tcggcaatcc agagacagcg gcgttatctg gctctggaga aagcttataa
    15001 cagaggataa ccgcgcatgg tgcttggcaa accgcaaaca gacccgactc tcgaatggtt
    15061 cttgtctcat tgccacattc ataagtaccc atccaagagc acgcttattc accagggtga
    15121 aaaagcggaa acgctgtact acatcgttaa aggctctgtg gcagtgctga tcaaagacga
    15181 agagggtaaa gaaatgatcc tctcctatct gaatcagggt gattttattg gcgaactggg
    15241 cctgtttgaa gagggccagg aacgtagcgc atgggtacgt gcgaaaaccg cctgtgaagt
    15301 ggctgaaatt tcgtacaaaa aatttcgcca attgattcag gtaaacccgg acattctgat
    15361 gcgtctgtct gcacagatgg cgcgtcgtct gcaagtcact tcagagaaag tgggcaacct
    15421 ggcgttcctc gacgtgacgg gccgcattgc acagactctg ctgaatctgg caaaacaacc
    15481 ggatgctatg actcacccgg acggtatgca aatcaaaatt acccgtcagg aaatcggtca
    15541 gattgtcggc tgttctcgtg aaaccgtggg acgcattctg aagatgctgg aagatcagaa
    15601 cctgatctcc gcacacggta aaaccatcgt cgtttacggc actcgttaat cccgtcagag
    15661 tggcgcgtta cctggtagcg cgccattttg tttcccccga tgtggcgcag actgatttat
    15721 caccccgata tcaactatgc acttcgacaa acgctggtgc tatgtttgcc cgtggccgtt
    15781 gggttaatgc ttggcgaatt acgattcggc ctgctcttct ccctcgttcc tgcctgttgc
    15841 aatattgcgg gccttgatac gcctcataaa cgttttttca aacgcttaat cattggtgcg
    15901 tcgctgtttg ccacctgtag cttgctgaca caggtgctac tggcaaaaga tgttcccctg
    15961 ccctttttgc tgaccggatt aacgctggta cttggcgtca ctgctgagct ggggccattg
    16021 cacgcaaaat tgcttcccgc atcgctgctc gccgccattt ttaccctcag tctggcggga
    16081 tacatgccgg tctgggaacc gttgctcatc tatgcgctgg gcactttgtg gtacggattg
    16141 tttaactggt tttggttctg gatctggcgc gaacaaccgc tacgcgagtc actaagtctg
    16201 ctgtaccgtg aactggcaga ttactgtgaa gccaaataca gcctgcttac ccagcacacc
    16261 gaccctgaaa aagcgctgcc gccgctgctg gtgcgccagc aaaaagcggt cgatctaatt
    16321 acccagtgct atcagcaaat gcatatgctt tccgcgcaaa ataataccga ttacaagcgg
    16381 atgctgcgta ttttccagga ggcgctggat ttgcaggaac atatttcggt cagtttgcat
    16441 cagccggaag aggtgcaaaa gctggtcgag cgtagccatg cggaagaagt tatccgctgg
    16501 aatgcgcaaa ccgtcgccgc tcgcctgcgc gtgctggctg atgacattct ttaccatcgc
    16561 ctgccaacgc gttttacgat ggaaaagcaa attggcgcac tggaaaaaat cgcccgccaa
    16621 cacccggata atccggttgg gcaattctgc tactggcatt tcagccgcat tgctcgtgtg
    16681 ctgcgcaccc aaaaaccgct ctatgcccgt gacttactgg ccgataaaca gcggcgaatg
    16741 ccattacttc cggcgctgaa aagttatctg tcactaaagt ctccagcgct acgcaatgcc
    16801 ggacgactca gtgtgatgtt aagcgttgcc agcctgatgg gcaccgcgct gcatctgccg
    16861 aagtcgtact ggatcctgat gacagtattg ctggtgacgc aaaatggcta tggcgcaacc
    16921 cgtctgagga ttgtaaatcg ctccgtagga accgtggtcg ggttaatcat tgcaggcgtg
    16981 gcgctacact ttaaaattcc cgaaggttac accctgacct tgatgctgat taccaccctc
    17041 gccagctacc tgatattgcg caaaaactac ggctgggcga cggtcggttt tactattacc
    17101 gcagtgtata ccctgcaact gttgtggctg aacggtgagc agtacatcct tccgcgtctt
    17161 atcgatacca ttattggttg tttaattgct ttcggcggta ctgtctggct gtggccgcag
    17221 tggcagagcg ggttattgcg taagaacgcc catgacgctt tagaagccta tcaggacgcg
    17281 attcgcttga ttctgagcga ggacccgcaa cctactccac tggcctggca gcgaatgcgg
    17341 gtaaatcagg cgcataatac tctgtataac tcattgaatc aggcgatgca ggaaccggcg
    17401 tttaacagcc attatctggc agatatgaaa ctgtgggtaa cgcacagcca gtttattgtt
    17461 gagcatatta atgccatgac cacgctggcg cgggaacacc gggcattgcc accggaactg
    17521 gcacaagagt atttacagtc ttgtgaaatc gccattcagc gttgtcagca gcgactggag
    17581 tatgacgaac cgggtagttc tggcgatgcc aatatcatgg atgcgccgga gatgcagccg
    17641 cacgaaggcg cggcaggtac gctggagcag catttacaac gggttattgg ccatctgaac
    17701 accatgcaca ccatttcgtc gatggcatgg cggcagcgac cgcatcacgg gatttggctg
    17761 agtcgcaagt tgcgggattc gaaggcgtaa tacaggctaa accatcggat gaggtgttca
    17821 cgccgcatcc gacatctttt gcctgatgcg tcttatttac gccccaacca ccttcgccac
    17881 cgcgtgggcg aaacgatgca tcccttcatc gatatccgca tcttccacca ccagcgacgg
    17941 cgcaaaacgc atcacatcag gcccggcatt cagcaccatt acgccttcct ctgcacccgc
    18001 atacaggaaa tcacgcgccc gacctttgta ctgtggtttc agctctgcgc caatcaacag
    18061 ccccataccg cgaatatcgc taaacacatc gtactgctga tcgatcttct gcaaatggtc
    18121 aacaaaacgc tggcgtttcg cctgaatacc ttccagcact tcaggggtat tgatgatatc
    18181 aaacgccgcg cccgctactg cacaggccag aggattaccg ccgtaggtgg aaccgtgaga
    18241 accaggatga aacgcggaag caatttccgc cgtggtcagc atggcgctaa tcgggaagcc
    18301 gccgcctaac gctttcgcag aggtcagaat atccggcgtc acgccgtagt gcatgtaagc
    18361 aaacaaatcg ccggtccgcc ccatcccgca ctgtacttca tcaaacacca ataatgcctg
    18421 atgttgatcg cacagctcgc gcaagccctg caaaaactct ggcgtcgctg ccgtcacacc
    18481 gccctcaccc tggatcggct caaccaccac cgcacaggtg tgatcatcca tcaccgcttt
    18541 cactgcgtgg agatcgttaa agggaacgtg gatgatgtct gccggttttg gcccaaagcc
    18601 atcggaatat tttggttgcc cgcccaccga gacggtaaac agcgagcgac catgaaaagc
    18661 gttatggaag gcgataattt tggttttgaa cgggctatga cgcacacagg cgtaatggcg
    18721 tgccagttta aaggcggttt cgttagcttc cgtgccggag ttcataaaca ccacgcgttc
    18781 ggcaaacgtt gcctcaatca gtttacgacc aagacgcagc gccggttcat tggtgaaaac
    18841 gttactgata tgccacagag tttcgccctg ggtttttaac gcgttcacca gcgcaggatg
    18901 gcaatggccc aacgccgtaa ctgcaatgcc acccgcgaaa tcgacatact ccttgccttg
    18961 ctgatcccag attcggctgc cctgaccttt taccggaata aactctgccg gagcataaat
    19021 cggcaggatc acttcatcga aagtcgcgcg tgtaattgct gtttgttcaa ttgccatctc
    19081 atgatcaccc tgttacgcat aaaccaatgt gaaattataa tcacaaaata tgcataaaaa
    19141 atcacttaat agcaatcaga aatcagcgat gcaggaaatt agccagcagt tgatgtcctt
    19201 gttcgctaag aatactttct ggatggaatt gcacaccttc cagatcccac tggcgatggc
    19261 gaatccccat aatctcgcgg gtttcgctcc aggccgtcac ttcaaagcac tccggtaatg
    19321 agtcaggttc caccaccagc gaatggtagc gtgtcacggt gagtggattt gccagcccct
    19381 taaatacgcc cacaccatta tgtgtaatcg gcgaggtttt gccgtgcatg acctttgcgg
    19441 cgcgcacaac tttgccgcca aatgcctgtg ccattgcctg gtgaccgagg cagacgccaa
    19501 gaatcggcaa acgcccggca tagtgacgaa taacgtcaag ggagatcccg gcttcatctg
    19561 gcgtacaggg gccgggtgag atgacaattt tttgtggttt aagggcgtcg atatccgcca
    19621 acgtcaacgc atcgttgcgc ttaaccaaca catccgcccc cagttcacaa aagtactggt
    19681 agaggttcca ggtaaaagaa tcgtagttat caataagcag gatcatggcg gctccggtac
    19741 gaaagaaccg cgctatttta ctcagattcc ccgacttcgc ttaccacttt gctaaatatc
    19801 atctgcagcg cggtgagatc ccccattgcc ccattctgat ttgcctgatt ccaggcctct
    19861 ttttcgatac cctgccagct cagttgatat ccggcatgaa tcgccagttg ctcgaagaag
    19921 atccgctgtg ccaaaccact tcccacccgg aagggatgca gcacgttgat ttcacaatag
    19981 taatgcgcca accgctcgac gaatttatct ttctcaaggc tagtcagata cttctcttcc
    20041 tccaaatcct gcatcagggc attgccctct ttttcgagat aggcaaagtg gcagaacggc
    20101 gtatctccct gataaatatc aacttcacgc agttgccctg cccagtcgaa aatatcctga
    20161 tacagctggc gatggatagt gcgcaaatgc ggtaaaccgc gcaccagcgg accaagctca
    20221 atggtcgcag cacgcagcgc cgtcatttcg taagcggcct gttccagccg ctgctgctgg
    20281 cggatgttga gcttgttacg catgatatcg agacccgggt agagatatgg atcgcgccct
    20341 tcgccgaatt tatcgctcat agtgcctcct cagcgcttca aggcgcgcta aagcctctgc
    20401 ggcagtaaga gtgactaaag gcatctcgac gccttcaaga cggcgactgg cctggaaatt
    20461 acgattacgc tgaagctccc agagacggga cttttgctta tcggtgagtt tcttcacttg
    20521 atgcctccct gaacgtgtcc atttgccaca agtataagcg gcaaatccgg gttacgccgg
    20581 gagagcagaa gcgcgggcaa gattgcccgc gcgagaaatc attacggcag gactttagcg
    20641 gaaaggataa ctaccggttt tgacggcaca ttctggtacg gaccaacgtc atgagtcggc
    20701 acctgggaaa tcttatcggc aacgtccatg cctttcacca ctttaccaaa taccgcgtaa
    20761 ccgaaatcac gctgaccgtg gtcaaggaag gcgttatcgg caacgttgat aaagaactgg
    20821 ctggtggcgc tgtctttgtc agcggtacgc gccatcgcga tggtgccacg cgtgttgcgc
    20881 aggccgttat cagcttcatt tttgattggc gggtttggtt ttttctgctg catctgctcg
    20941 gtgaaaccgc cgccctgaat cataaagcca ggaatgacgc ggtgaaaggt cgtgttgtta
    21001 taaaaaccac tgttcacata atcgacaaag ttttgcacag acactggcgc tttttgttta
    21061 tccagctcca gttcgatgtt accagctgag gttgtcaaca atacgtgcgg gtcccctttc
    21121 gctgccattg ctgcgggaga aagagcagaa agagcgaaaa cagcagccat cgccgccagg
    21181 gtcgatttga acatgagatt tccttaacaa acagagcaga aaaaaagcaa gtgaagagat
    21241 tctaaatagc cttcaagaac aaggccatcc ctttacctaa ttttacgtat ctgaaatata
    21301 tgtaacctga ggataacttt ttattccgtg atcaaaatca cctcttaaaa tgcaatttag
    21361 caaccgattg caataaaaca tttaatcaga tcacaaaatc gcctaaaatc gcccgctcgc
    21421 ggcatagccc gctatgccat tttatttttg aacgcaggcc aatcatgact aacagcaatc
    21481 gcatcaagct cacatggatt agctttcttt cctacgcact gaccggtgcg ttggttattg
    21541 tcaccgggat ggtgatggga aatatcgccg attatttcaa tctgcctgtt tccagcatga
    21601 gtaacacctt caccttcctc aatgccggca ttttaatctc tatcttcctc aacgcctggc
    21661 tgatggaaat cgtcccgttg aaaacgcagt tacgttttgg ctttctcctg atggtgctgg
    21721 cggttgccgg tttgatgttc agccacagcc tggcgctgtt ctcggcggcg atgttcattc
    21781 tcggggtggt cagcggcatc accatgtcga ttggtacatt cctggtaaca caaatgtatg
    21841 aaggacgtca gcgcggttca cgcctgttat ttaccgactc cttcttcagt atggccggga
    21901 tgattttccc aatgatcgcc gcatttctgc tggcgcgtag cattgagtgg tactgggttt
    21961 atgcctgcat cgggctggtg tatgtcgcta tttttattct gaccttcggc tgtgagttcc
    22021 cggcgctggg caaacatgcg cccaaaacgg atgctccggt agagaaagaa aagtggggga
    22081 tcggcgtact gtttctctct gttgcggcgc tgtgctacat cctcggtcag ttaggtttta
    22141 tctcctgggt gccggaatat gccaaaggcc tgggcatgag cctgaacgac gcaggcacgc
    22201 tggtaagtaa cttctggatg tcgtacatgg tcggcatgtg ggcattcagc tttattcttc
    22261 gcttctttga tttgcaacgt atcctgaccg tactggctgg tctggctgcg attctgatgt
    22321 acgtctttaa caccggaaca ccggcacata tggcgtggtc aattctcgcc ctgggcttct
    22381 tctccagcgc gatctatacc accatcatca ccctgggttc acagcagacc aaagtaccgt
    22441 cgccaaaact ggttaacttt gtcctgacct gcgggaccat cggtactatg ttgacctttg
    22501 tggttaccgg cccgattgtt gaacatagtg gtccgcaggc ggcgctgctg acggcaaacg
    22561 gtctgtacgc tgtcgtcttt gtgatgtgct tcctgttagg tttcgtcagc cgtcaccgtc
    22621 agcataacac cctgacctct cattaattgt tcatgccggg cggcactatc gtcgtccggc
    22681 cttttcctct cttaccctgc tacgtgcatc tatttctata aacccgttca atttgtctgt
    22741 tttttgcaca aacatgaaat atcagacaat tccgtgactt aagaaaattt atacaaatca
    22801 gcaatatacc ccttaaggag tatataaagg tgaatttgat ttacatcaat aagcggggtt
    22861 gctgaatcgt taaggtaggc ggtaatagaa aagaaatcga ggcaaaaatg agcaaagtca
    22921 gactcgcaat tatcggtaac ggtatggtcg gccatcgctt tatcgaagat cttcttgata
    22981 aatctgatgc ggccaacttt gatattaccg ttttctgtga agaaccgcgc atcgcttatg
    23041 accgcgtaca cctctcgtct tacttctctc accacaccgc cgaagagctg tcgctggtgc
    23101 gcgaaggctt ctacgagaaa cacggcatca aagttctggt cggcgaacgc gctatcacca
    23161 tcaaccgtca ggagaaggtg attcactcca gcgccggacg taccgttttt tatgacaagc
    23221 tgatcatggc gaccggttcc tacccgtgga tcccgccaat caaaggttct gatactcagg
    23281 actgctttgt ctatcgcact attgaagacc tcaacgccat tgaatcctgc gcccgtcgca
    23341 gcaaacgcgg tgccgttgtt ggtggcggcc tgttaggtct ggaagccgct ggcgcgctga
    23401 aaaacttagg cattgaaacc cacgttatcg aatttgcccc tatgctgatg gcggaacagc
    23461 ttgatcagat gggcggcgag cagctgcgtc gcaaaatcga aagtatgggc gtgcgcgttc
    23521 acaccagcaa aaacactctt gagattgtgc aggaaggtgt tgaagcgcgt aaaaccatgc
    23581 gttttgccga cggcagcgaa ctggaagtcg actttatcgt cttctctacc ggtatccgtc
    23641 cgcgcgataa gctggcaacc cagtgtggtc tggacgttgc tccgcgtggg ggtatcgtca
    23701 taaatgattc ctgccagact tccgatccgg atatctacgc catcggtgaa tgcgcaagct
    23761 ggaacaaccg tgtatttggt ctggtagcac caggctacaa aatggcgcag gtcgccgttg
    23821 accatattct tggtagcgaa aacgcctttg aaggtgcaga ccttagcgcc aagctgaaac
    23881 tgctgggcgt agacgtaggc ggtattggtg atgcgcacgg tcgcacgcct ggcgcacgta
    23941 gctacgttta cctcgacgaa agcaaagaga tctacaaacg cctgattgtc agcgaagaca
    24001 acaaaaccct gctcggtgcg gtactggtgg gcgataccag cgactacggc aacctgctgc
    24061 aactggtgct gaacgctatc gaactgccgg aaaacccgga ttctctgatt ctgccggcgc
    24121 actcgggtag cggtaagccg tctatcggtg ttgataaact gccggacagc gcgcaaatct
    24181 gctcctgctt cgacgtcacc aaaggcgacc tgattgctgc tatcaacaaa ggctgccaca
    24241 ccgttgcggc gctgaaagcc gaaaccaaag ccggtacggg ctgcggcggt tgtattccgc
    24301 tggtcactca ggtactgaac gcggaactgg cgaaacaggg tatcgaagtt aacaacaacc
    24361 tgtgtgaaca ctttgcttat tcgcgtcagg aactgttcca tttgatccgc gttgaaggca
    24421 ttaaaacctt cgaagaactg ctggcgaaac acggcaaagg ttacggttgt gaagtttgta
    24481 aaccgaccgt cggttcgctg ctggcctcct gctggaacga atacattctg aagccggaac
    24541 atactccgct gcaggattct aacgacaact tcctcgctaa catccaaaaa gacggcacct
    24601 actcggtgat cccgcgttct ccgggtggtg aaatcacccc ggaagggctg atggcagtgg
    24661 gtcgtatcgc gcgtgaattt aatctctaca ccaaaatcac cggctcccag cgcctggcga
    24721 tgtttggcgc acagaaagac gatctgccgg agatctggcg tcagctgatt gaagcaggtt
    24781 tcgaaaccgg tcatgcctat gcgaaagcac tgcgtatggc gaaaacctgc gtgggtagca
    24841 cctggtgccg ctatggcgtt ggcgacagcg tcggcctcgg cgtggaactg gaaaatcgct
    24901 acaaaggcat ccgtacgccg cacaaaatga agttcggtgt ctccggctgt acccgtgaat
    24961 gttcagaagc tcagggtaaa gacgtgggta ttatcgccac tgaaaaaggc tggaacctgt
    25021 atgtttgcgg taacggcggc atgaaaccgc gtcatgcgga tctgctggca gcggatatcg
    25081 atcgcgaaac gctgattaaa tatcttgacc gcttcatgat gttctacatc cgtactgccg
    25141 acaaactgac gcgtaccgcg ccgtggttag aaaacctcga aggtggcatc gattacctga
    25201 aagcggtgat cattgacgac aaactggggc tgaacgcaca tctggaagaa gagatggcgc
    25261 gcctgcgtga agcggtagtg tgtgagtgga ctgaaacggt caataccccg tctgcgcaga
    25321 ctcgcttcaa acacttcatc aacagcgaca agcgtgaccc gaacgtgcag atggtgccag
    25381 agcgcgaaca gcaccgtccg gcaacgccgt atgaacgtat cccggtaact ctggtggagg
    25441 acaacgcatg agccagtgga aagacatctg caaaatcgat gacatcctgc ctgaaaccgg
    25501 cgtctgcgcg ctgttaggtg acgaacaagt agcaattttc cgcccgtatc acagcgacca
    25561 ggtgtttgcg atcagcaaca tcgatccgtt cttcgagtcc agcgtgctgt cacgcgggct
    25621 gattgcggaa caccagggcg agctgtgggt cgccagcccg ctgaaaaagc agcgttttcg
    25681 cttaagcgac ggcttgtgca tggaagacga acagttttcc gtcaagcatt acgacgcgcg
    25741 agtgaaagac ggcgtggtgc agctgcgcgg ttaatatttt aacgggaggc gcaatgcctc
    25801 cccctttttg catggtcctg taataacctt cggtatattg caggacattt tttaaacttt
    25861 ttgttttatt ttttgttttt attttttaaa ggataatcaa atgtttacag acactattac
    25921 taagtgtgcg gctaacgctg cgcgcattgc acgcctgtcg gcaaataacc cgctcggctt
    25981 ttgggtcagc tccgccatgg cgggcgcgta tgtgggtctt gggatcatcc tgattttcac
    26041 gctcggtaat ttgctcgacc cgtccgtacg tcctctggtg atgggtgcga cctttggtat
    26101 cgccttaacg ctggtgatta tcgccggttc tgaactgttc accggacaca ccatgttcct
    26161 cacctttgga gtgaaagcgg gcactatcag ccacgggcaa atgtgggcaa tcctgccgca
    26221 aacctggctg ggtaacctgg tcggttccgt ctttgttgcc atgctctata gctggggtgg
    26281 cggtagcctg ctgccggtcg ataccagcat cgttcactcc gtcgcgctgg ctaaaaccac
    26341 tgcaccggca atggtactgt tcttcaaagg tgcattgtgt aactggctgg tttgcctggc
    26401 aatctggatg gcgctgcgca ctgaaggggc ggcgaaattt atcgctatct ggtggtgttt
    26461 gctggcattt atcgcgtccg gctacgagca ctccatcgct aacatgacgc tgttcgccct
    26521 ctcctggttc ggcaaccaca gcgaagccta cacgctggcg ggtattggtc ataacctgct
    26581 gtgggtgacg ctgggtaata ctttatcggg tgccgtattc atgggattgg gttattggta
    26641 tgctacgccg aaagcgaatc gtccggttgc ggacaaattt aatcaaactg aaacggctgc
    26701 cggttaatta ttaaggggtt tttacgtgga tcatttgcct atattttgcc aattacgcga
    26761 tcgcgactgt ctgattgtcg gcggtggtga tgtcgcggaa cgcaaagcaa ggttgctgtt
    26821 agacgcaggc gctcgcttaa cggtgaatgc attagcgttt attccacagt tcaccgcatg
    26881 ggcagatgca ggcatgttaa ccctcgtcga agggccattt gatgaaagcc ttctcgacac
    26941 ctgctggctg gcgattgcag cgacggatga tgacgcgctt aaccagcgcg tcagcgaagc
    27001 cgctgaagct cgtcgcatct tctgtaacgt ggtcgatgcg ccgaaagccg ccagctttat
    27061 tatgccgtcg attattgacc gctcgccgct catggtagcg gtctcctctg gcggcacctc
    27121 tccggttctg gcgcgcctgt tgcgcgaaaa actcgaatca ctgctgccgt tacatctggg
    27181 ccaggtagcg aaatacgccg ggcaattacg cgggcgagtg aaacaacagt tcgccacgat
    27241 gggtgagcgt cgccgtttct gggagaaatt gttcgttaat gaccgcctgg cgcagtcgct
    27301 ggccaacaac gatcagaaag ccattactga aaccaccgaa cagttaatca atgaaccgct
    27361 cgatcatcgc ggtgaagtgg tgctggttgg tgcaggtccg ggcgatgccg ggctgctgac
    27421 actgaaaggt ctgcaacaaa ttcagcaggc agatgtggtg gtctacgacc gtctggtttc
    27481 tgacgatatt atgaatctgg tacgccgcga tgctgatcgc gttttcgtcg gcaaacgcgc
    27541 gggataccac tgcgtaccgc aggaagagat taaccagatc ctgctgcggg aagcgcaaaa
    27601 aggcaaacgc gtggtgcggc tgaaaggcgg cgatccgttt atttttggcc gtggtggcga
    27661 agagctggaa acactgtgca acgcgggtat tccattctcg gtggttccgg gtattaccgc
    27721 agcctctggt tgctctgcct attcgggtat tccgctcacg catcgcgatt atgcccagag
    27781 cgtacgctta attactggac acttaaaaac cggtggcgag ctggactggg aaaacctggc
    27841 ggcagaaaaa cagacgctgg tgttttatat ggggctgaat caggctgcaa ctattcagca
    27901 aaagctgatt gaatacggta tgcctggtga aatgccggta gcaattgtcg aaaacggaac
    27961 ggcagtcacg cagcgcgtga ttgacggtac gctcacgcag ctgggcgaac tggcgcagca
    28021 aatgaacagt ccatcgctaa ttattattgg tcgggttgtt ggcctgcgcg ataaattgaa
    28081 ctggttctct aaccattaat ttaaccaggg ccagagaagt ctggcctttt tcgtttacaa
    28141 ctctctttat atattcagca gataaaaata taacccctta ataaatattg tctgctaatg
    28201 ggttatattc accgttacag caacttacaa aattaagcca atcgctcac
//
LOCUS       DAPOXO010000069        27348 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPOXO010000069 DAPOXO010000000
VERSION     DAPOXO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27348
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.069"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(47..1216)
                     /locus_tag="ROH59_003475"
     CDS             complement(47..1216)
                     /locus_tag="ROH59_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HDX4805916.1"
                     /translation="MQGNALTVLLSGKKYLLLQGPMGPFFSDVAEWLESLGRNAVNVV
                     FNGGDRFYCRHRQYLAYYQTPKEFPGWLRDLHRQYDFDTILCFGDCRPLHKEAKRWAK
                     SKGIRFLAFEEGYLRPQFITVEEGGVNAYSSLPRDPDFYRKLPDMPTPHVENLKPSTM
                     KRIGHAMWYYLMGWHYRHEFPRYRHHKSFSPWYEARCWVRAYWRKQLYKVTQRKVLPR
                     LMNELDQRYYLAVLQVYNDSQIRNHSSYNDVRDYINEVMYSFSRKAPKESYLVIKHHP
                     MDRGHRLYRPLIKRLSKEYGLGERILYVHDLPMPELLRHAKAVVTINSTAGISALIHN
                     KPLKVMGNALYDIKGLTYQGHLHQFWQADFKPDMKLFKKFRGYLLVKTQVNAVYY"
     gene            complement(1251..3278)
                     /locus_tag="ROH59_003476"
     CDS             complement(1251..3278)
                     /locus_tag="ROH59_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HDX4805917.1"
                     /translation="MIGIYSPGIWRIPHLEIFLAQPCQKLSLLRPVPQEVDAIAVWGH
                     RPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGEPPLSLVVDDCCIYYDASKPSAL
                     EKLVQDKAGNTALISQAREAMHTIVTGDLSKYNLAPAFVADESERSDIVLVVDQTFND
                     MSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFAALRATQRVRLI
                     AENVSPQSLLRHVSRVYVVTSQYGFEALLAGKPVTCFGQPWYAGWGLTDDRHPQSALL
                     SARRGSATLEELFAAAYLRYCRYIDPQTGEVSNLFTVLQWLQLQRRHLQQRNGYLWAP
                     GLTLWKSAILKPFLQTATNRLSFSRRCTAASACVVWGVKGEQQWRAEAQRKSLPLWRM
                     EDGFLRSSGLGSDLLPPLSLVLDKRGIYYDATRPSDLEVLLNHSQLTLAQQMRAEKLR
                     QRLVESKLSKYNLGADFSLPAEAKDKKIILVPGQVEDDASIKTGTVSIKSNLELLRTV
                     RERTPHAYIIYKPHPDVLVGNRKGNIPTELIAELADYQALDADIIQCIQRADEVHTMT
                     SLSGFEALLHGKQVHCYGLPFYAGWGLTVDEHHCPRREQKLTIADLIYQALIVYPTYI
                     HPTLLQPITVEEAAEYLIQTPRKPMFITRKKAGRVIRYYRKLIMFCKVRFG"
     gene            complement(3275..4015)
                     /gene="kdsB"
                     /locus_tag="ROH59_003477"
     CDS             complement(3275..4015)
                     /gene="kdsB"
                     /locus_tag="ROH59_003477"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001578967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HDX4805918.1"
                     /translation="MSKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQVAGV
                     AEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRLVEVMHKVEADIYINLQGDEPM
                     IRPRDVETLLQGMRDDPALPVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIP
                     YPRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESLEQLRLMNAGINIRTFEV
                     AATGPGVDTPACLEKVRALMAQELAENA"
     gene            complement(4025..5701)
                     /locus_tag="ROH59_003478"
     CDS             complement(4025..5701)
                     /locus_tag="ROH59_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialic acid transporter KpsD"
                     /protein_id="HDX4805919.1"
                     /translation="MKLFKSILLIAACHAAQASATIDINADPNLTGAAPLTGILNGQK
                     SDTQNMSGFDNTPPPAPPVVMSRMFGAQLFNGTSADSGATVGFNPDYILNPGDSIQVR
                     LWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQSNVNVYAS
                     LLQAQPVKVYVTGFVRNPGLYGGVTSDSLLNYLIKAGGVDPERGSYVDIVVKRGNRVR
                     SNVNLYDFLLNGKLGLSQFADGDTIIVGPRQHTFSVQGDVFNSYDFEFRESSIPVTEA
                     LSWARPKPGATHITIMRKQGLQKRSEYYPISSAPGRMLQNGDTLIVSTDRYAGTIQVR
                     VEGAHSGEHAMVLPYGSTMRAVLEKVRPNSMSQMNAVQLYRPSVAQRQKEMLNLSLQK
                     LEEASLSAQSSTKEEASLRMQEAQLISRFVAKARTVVPKGEVILNESNIDSVLLEDGD
                     VINIPEKTSLVMVHGEVLFPNAVSWQKGMTTEDYIEKCGGLTQKSGNARIIVIRQNGA
                     AVNAEDVDSLKPGDEIMVLPKYESKNIEVTRGISTILYQLAVGAKVILSL"
     gene            complement(5725..6873)
                     /locus_tag="ROH59_003479"
     CDS             complement(5725..6873)
                     /locus_tag="ROH59_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide export inner-membrane
                     protein KpsE"
                     /protein_id="HDX4805920.1"
                     /translation="MLIKVKSAVSWMRARLSAISLADIQKHLAKIIILAPMAVLLIYL
                     AIFSQPRYMSESKVAIKRSDDLNSGSLNFGLLLGASNPSSAEDALYLKEYINSPDMLA
                     ALDKQLNFREAFSHSGLDFLNHLSKDETAEGFLKYYKDRINVSYDDKTGLLNIQTQGF
                     SPEFALKFNQTVLKESERFINEMSHRIARDQLAFAETEMEKARQRLDASKAELLSYQD
                     NNNVLDPQAQAQAASTLVNTLMGQKIQMEADLRNLLTYLREDAPQVVSARNAIQSLQA
                     QIDEEKSKITAPQGDKLNRMAVDFEEIKSKVEFNTELYKLTLTSIEKTRVEAARKLKV
                     LSVISSPQLPQESSFPNIPYLIACWLLVCCLLFGTLKLLLAVIEDHRD"
     gene            complement(6945..7928)
                     /locus_tag="ROH59_003480"
     CDS             complement(6945..7928)
                     /locus_tag="ROH59_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HDX4805921.1"
                     /translation="MSERHLPDDQSSTIDPYLITSVRQTLAEQSAALQNLSKQLDSGQ
                     YQRVLNLIMNCKGHVILSGMGKSGHVGRKMSATLASTGTPSFFIHPAEAFHGDLGMIT
                     PYDLLILISASGETDEILKLVPSLKNFGNRIIAITNNGNSTLAKNADAVLELHMANET
                     CPNNLAPTTSTTLTMAIGDALAIAMIHQRKFMPNDFARYHPGGSLGRRLLTRVADVMQ
                     HDVPAVQLDASFKTVIQRITSGCQGMVMVEDAEGGLAGIITDGDLRRFMEKEDSLTSA
                     TAAQMMTREPLTLPEDTMIIEAEEKMQKHRVSTLLVTNKANKVTGLVRIFD"
     gene            complement(8738..8893)
                     /locus_tag="ROH59_003481"
     CDS             complement(8738..8893)
                     /locus_tag="ROH59_003481"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805922.1"
                     /translation="MAALVVTWFNPVKEAFYMHLPAAGKTKKVALVDCMRKLLTILNA
                     MLRKNEE"
     gene            complement(9325..10258)
                     /locus_tag="ROH59_003482"
                     /pseudo
     CDS             complement(9325..10258)
                     /locus_tag="ROH59_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536504.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
     gene            complement(10251..10646)
                     /locus_tag="ROH59_003483"
     CDS             complement(10251..10646)
                     /locus_tag="ROH59_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000208382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HDX4805923.1"
                     /translation="MTTKDRIQSRLNRSKRYVFTRDDFRDIAGYDQVGRALRTLVNEG
                     KLMKVGYGVYTKARRNIITGKIMPAAPGGSAAVITEALERLNIRYRLAGATECYNKSQ
                     STQIPVSLGIKTPSRFKRMLIVGKSKINA"
     gene            complement(10715..11560)
                     /locus_tag="ROH59_003484"
     CDS             complement(10715..11560)
                     /locus_tag="ROH59_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HDX4805924.1"
                     /translation="MSDITISRPELVNGHTDVICSTSIRHILAVRKSALLQIDTLIRQ
                     LAEISVLTESIGGKTALDWAMKQDFRCGCWLMEKPETAMKAITRNLDREIWRDLMQHS
                     GMLSLMDAQAHDTWYRSLEYDNFPEISEANILSTFEQLHQNKDDVFERGVINLFRGLS
                     WNYKTNCPCKFGNKIIVNNLVRWDRWGLHLITGQQADRLADLERMLHLFSGKPIPDSR
                     ENIIIRLDDHIRSVQGKACYEDEMFSIRYFKKGSAHITFRKPELVDRLNDIIARHYPN
                     VLADR"
     gene            complement(11645..11842)
                     /locus_tag="ROH59_003485"
     CDS             complement(11645..11842)
                     /locus_tag="ROH59_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDX4805925.1"
                     /translation="MKSLTTETALYILIAWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IKQAREDIRTLRQLQLLQQNR"
     gene            complement(11859..12347)
                     /locus_tag="ROH59_003486"
     CDS             complement(11859..12347)
                     /locus_tag="ROH59_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805926.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDVDGVELAELINVVCDNGYS
                     LRVVDESDRTSTDSIPPSAALSGIRCSTAHITETDNAWLYSLSHQTNDTGESEWIHFT
                     GSGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLTRRYGVSLIHLDASTECLPDLPTF
                     DW"
     gene            complement(12344..12721)
                     /locus_tag="ROH59_003487"
     CDS             complement(12344..12721)
                     /locus_tag="ROH59_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDX4805927.1"
                     /translation="MKTLPDTHVRAASRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYAQVRTDQPGFSAGAPSQLINSIDILRARRATG
                     LMTRNNYRMVNNITQGKHPEAKR"
     gene            complement(12810..13178)
                     /locus_tag="ROH59_003488"
     CDS             complement(12810..13178)
                     /locus_tag="ROH59_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDX4805928.1"
                     /translation="MSDTLPGTTLPDDNKDLPWWGLPCTVTPCFGACLVQEGNRLHYL
                     ADRAGIRGRFSDADAYHPDQAFPLLMKQPELMLTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCDYVYLAVYPTPEMKN"
     gene            complement(13228..13872)
                     /locus_tag="ROH59_003489"
     CDS             complement(13228..13872)
                     /locus_tag="ROH59_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of toxin-antitoxin stability system"
                     /protein_id="HDX4805929.1"
                     /translation="MSSIITITVYTLDELSCPARGKARDWYRQHHADSNWYENVYEDF
                     REVCGIFGIDLRQRVFRLSNGRFMEEPCIWFSGFCSQGDGACFEGRWHWQPATPRKIR
                     EYAPQDRELHRIADTLQAVQKRNFWQLQAEISHRGRYCHPYSMDITVTRNSPTGQAMT
                     TDAEAAVSEALRDLAFWLYRQLENKYDWLTSDTAVDEALLINEYTFTEAGLRAG"
     gene            complement(13891..14112)
                     /locus_tag="ROH59_003490"
     CDS             complement(13891..14112)
                     /locus_tag="ROH59_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDX4805930.1"
                     /translation="MKIITRGEAMRIHQQHPTSRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            complement(14175..14651)
                     /locus_tag="ROH59_003491"
     CDS             complement(14175..14651)
                     /locus_tag="ROH59_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HDX4805931.1"
                     /translation="MQQLSFLPGEMTPGERSLILRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL"
     gene            complement(14667..15152)
                     /locus_tag="ROH59_003492"
     CDS             complement(14667..15152)
                     /locus_tag="ROH59_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX4805932.1"
                     /translation="MKTISHNSTTSSVSVTAASGNDQPQLVATIVPDEQRISFWPQHF
                     GLIPQWVALEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNA
                     MNGNRAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRII
                     D"
     gene            complement(15207..16025)
                     /locus_tag="ROH59_003493"
     CDS             complement(15207..16025)
                     /locus_tag="ROH59_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDX4805933.1"
                     /translation="MRLASRFGYANQIRRDRPLTHEELMHYVPGIFGEDKHTSRSQNY
                     TYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLILPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESLR"
     gene            complement(16126..16359)
                     /locus_tag="ROH59_003494"
     CDS             complement(16126..16359)
                     /locus_tag="ROH59_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001119724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDX4805934.1"
                     /translation="MLGYTEYVLAEGSFSYGQAVAVITAYRNVFIQDDPGMHFRRVIR
                     NAEGQRRWRCRNSEADAGKQLNAWLASGGLLRQ"
     gene            complement(16438..16893)
                     /locus_tag="ROH59_003495"
     CDS             complement(16438..16893)
                     /locus_tag="ROH59_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805935.1"
                     /translation="MIHLFKTCMITAFILGLTWSAPLRAQDQRYISIRNTDTIWLPGN
                     ICAYQFRLDNGGNDEGFGPLTITLQLKDKYGQTLVTRKMETEAFGDSNATRTTDAFLE
                     TECVENVATTEIIKATEESNGHRVSLPLSVFDPQDYHPLLITVSGKNVN"
     gene            complement(16969..18096)
                     /locus_tag="ROH59_003496"
                     /pseudo
     CDS             complement(16969..18096)
                     /locus_tag="ROH59_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708766.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18191..21313)
                     /gene="ag43"
                     /locus_tag="ROH59_003497"
     CDS             complement(18191..21313)
                     /gene="ag43"
                     /locus_tag="ROH59_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDX4805936.1"
                     /translation="MKRHLNTCYRLVWNHITGAFVVASELARARGKRGGVAVALSLAA
                     VTSLPVLAADIVVHPCETVNGGTLVNHDNQFVSGTADGVTVSTGLELGPDSDENTGGQ
                     WIKAGGTGRNTTVTANGRQIVQAGGTASDTVIRDGGGQSLNGLAVNTTLDNRGEQWVH
                     GGGKAAGTIINQDGYQTIKHGGLATGTIVNTGAEGGPESENVSSGQMVGGTAESTTIN
                     KNGRQVIWSSGMARDTLIYAGGDQTVHGEAHNTRLEGGNQYVHNGGTATETLINRDGW
                     QVIKEGGTAAHTTINQKGKLQVNAGGKASDVTQNTGGALVTSTAATVTGTNRLGAFSV
                     VAGKADNVVLENGGRLDVLSGHTATNTRVDDGGTLDIRNGGAATTVSMGNGGVLLADS
                     GAAVSGTRSDGKAFSIGGGQADALMLEKGSSFTLNAGDTATDTTVNGGLFTARGGTLA
                     GTTTLNNGATLTLSGKTVNNDTLTIREGDALLQGGALTGNGSVEKSGSGTLTVSNTTL
                     TQKAVNLNEGTLTLNDSTVTTDVIAQRGTALKLTGSTVLNGAIDPTNVTLTSGATWNI
                     PDNATVQSVVDDLSHAGQIHFTSARTGKFVPTTLQVKNLNGQNGTISLRVRPDMAQNN
                     ADRLVIDGGRATGKTILNLVNAGNSGTGLATTGKGIQVVEAINGATTEEGAFVQGNML
                     QAGAFNYTLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRILAGSRSHQTGVNG
                     ENNSVRLSIQGGHLGHDNNGGIVRGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVY
                     GAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASS
                     DNNDFRARGRGWQGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHG
                     SAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSTKHGVSELPVNWWVQPSVIRTFSSRG
                     DMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARVRENITLGVQAGYAHSVSGNSAEGY
                     NGQATLNVTF"
     gene            complement(21647..22519)
                     /locus_tag="ROH59_003498"
     CDS             complement(21647..22519)
                     /locus_tag="ROH59_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDX4805937.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTRHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVQRFRLSGHGYSMVITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILQCGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWEVDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRAQAREQFTGAVDRIFDTAESVCVASVARTVLRAVRDT
                     VVSVARAVWNWIFF"
     gene            23851..25341
                     /locus_tag="ROH59_003499"
     CDS             23851..25341
                     /locus_tag="ROH59_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HDX4805938.1"
                     /translation="MPYFQYPDEFPLSSLPPLIRDAVIEAQQITQAPLGLVAASALGA
                     VSLVCQNLIDVCRLNTLRGPVSLFLLTLAESGERKTAVDKLLMEPLYQQEMLLYSRHK
                     NELTTWKNKEELLKAQKKALLSKLNKELRKGADESETLRQLEALQKNRGEKPVRYKFI
                     FNDATTAAIKNQLCGKWRSVGIMSDEAGIIFDGYTLSELPFINKMWDGSVLSVDRKNE
                     PEQMIENARMTLSLMVQPGLFDRYMERKGSVARDSGFLARCLISKPATTQGKRFINGA
                     VTPGGSLTAFHERLMELARGSIEKSSKDERYCLHFSPEAQKIFIDHYNVLEQDLSPSG
                     PLSQFRGHVSKKTENIARIAALLQYFSQGEGKISADIMTSAVVISSWYTDEYKKLFAL
                     PDESELQLQDARELLDWLIEECRGECPPRVRKNYILQCGPGRFRNRKKLNVLLNILAS
                     QLRLSVVQEGKTTYVLLSEINNITLPELNACYSQKLIRWHEQSFGL"
     gene            complement(25462..26034)
                     /locus_tag="ROH59_003500"
     CDS             complement(25462..26034)
                     /locus_tag="ROH59_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4805939.1"
                     /translation="MQKLENRCELLLIQHQKWMTNVTRLIVAHGMGAPHLHGYHRLTL
                     AHFFLPEKGTIISVAPQGLYQVVNPGTPPFIPAIQEGLMTSIQTHEIMLLTHFNLGGV
                     LLSELHRLGENRLANRLNSLLRRFDDRDLYHTLIWLCWYDLMCAHSMQPWTEELKHKS
                     HAELENWAVARKREKRELELMIDEYLLYAC"
     gene            complement(26120..26326)
                     /locus_tag="ROH59_003501"
     CDS             complement(26120..26326)
                     /locus_tag="ROH59_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDX4805940.1"
                     /translation="MNTPVSLMDDQMVDMSFITQLTGLTDKWFYKLIKDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARITQSRP"
     gene            27274..>27348
                     /locus_tag="ROH59_003502"
     CDS             27274..>27348
                     /locus_tag="ROH59_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
                     /protein_id="HDX4805941.1"
                     /translation="MEKVISHTRYKLTPAELEAFNSAVD"
BASE COUNT         6501 a         6827 c         6934 g         7086 t
ORIGIN      
        1 atctgttatg attgatataa tggagatgtc gattgttgat aagatgttaa taataaaccg
       61 cattaacctg cgtcttcacc aataaatacc cacgaaactt cttaaacagt ttcatatctg
      121 gtttaaaatc agcctgccag aactggtgca aatgcccttg atacgtcaag cccttgatgt
      181 cgtacagggc attgcccatc actttgagtg gtttgttatg aatcagcgca gagatccccg
      241 ccgtactgtt aatcgtcacc accgcttttg catggcgtaa taattccggc atcgggagat
      301 cgtgcacata aaggattcgc tcacctaagc catattcctt actcaaccgt ttaattaatg
      361 gtcgatagag tctgtgacca cgatccatcg gatgatgttt gatcaccaaa taactttctt
      421 tcggcgcttt acgcgaaaat gagtacatga cttcattaat atagtcacgc acatcgttat
      481 aactgctgtg gttacgaatc tggctatcgt tatacacctg caaaacagca agataataac
      541 gctggtccag ttcgttcatt aacctcggta ataccttacg ctgtgttacc ttgtaaagtt
      601 gcttgcgcca gtatgcacga acccagcaac gtgcttcata ccagggggaa aatgatttgt
      661 ggtggcggta gcgaggaaac tcatgacggt aatgccagcc catcaggtaa taccacatag
      721 catggcctat acgtttcatc gttgaaggtt ttaagttctc aacgtgcggc gtaggcatat
      781 ctggtaactt acgataaaaa tccggatcgc gcggtagcga tgaatatgcg ttcactccgc
      841 cttcttcaac ggtaataaat tgcgggcgta aatatccttc ttcaaatgcc aggaagcgga
      901 tccctttcga ctttgcccag cgttttgctt ctttatgcaa tgggcggcag tcgccaaagc
      961 agaggattgt gtcaaagtca tattgccggt ggagatcccg taaccatccg ggaaactctt
     1021 tcggtgtctg gtagtaagct aggtattgtc gatggcggca gtaaaaacga tccccaccgt
     1081 tgaatacaac attcacagcg ttacgaccta atgactctag ccactcggca acatcactga
     1141 aaaagggtcc cattggcccc tgcaatagca gatatttttt accggataat aaaacggtta
     1201 gtgcattacc ttgcataaat aatttgtgta atagtcaact gtgaaattgt ttagccaaat
     1261 ctgaccttgc agaacataat taatttgcgg taatagcgta ttactcgtcc cgcttttttt
     1321 cgggtaataa acatcggctt gcgcggcgtc tggatcaaat attccgccgc ctcttcaacc
     1381 gtaataggtt gtagcagtgt tgggtggata taggttggat aaacaatcaa cgcctgatag
     1441 atcaaatctg ctatcgttaa tttttgctcg cgacgcgggc agtgatgttc atcaacggtt
     1501 aaaccccaac cggcatagaa gggcaggccg taacaatgaa cttgcttgcc atgtaataac
     1561 gcttcaaacc cggacaatga tgtcatggtg tgcacttcat ctgcgcgctg aatgcattga
     1621 ataatatctg cgtccagtgc ctgataatca gcgagttcag caattagttc tgtcggaata
     1681 ttgcccttgc gattccccac cagtacatcc gggtgcggtt tataaataat gtaagcgtgc
     1741 ggagtgcgct cgcgtactgt gcgtaataac tcaaggttgc tcttaatcga cacagtgcct
     1801 gttttaattg aggcatcgtc ttctacctga cccggcacca ggatgatttt tttatctttg
     1861 gcctcggcag gcagagagaa atcggccccc aggttgtatt tgctcagttt gctttcaacc
     1921 agtcgctggc gtaatttttc agctcgcatc tgctgcgcca gtgttaactg gctgtgatta
     1981 agcagcactt ccaggtcgct ggggcgcgtg gcgtcatagt agatcccgcg tttatccagg
     2041 accaacgata gcggcggcaa aaggtcagag ccaagtccgg atgaacgtag aaaaccatct
     2101 tccattcgcc ataacggcag tgattttcgc tgcgcttcgg ctcgccattg ctgttctccc
     2161 tttacacccc ataccacgca ggcgctcgcc gcagtacagc gacgtgaaaa actcagccgg
     2221 tttgttgccg tttgcaagaa aggtttcagg atcgctgact tccacagcgt taagcctggc
     2281 gcccataaat aaccattacg ctgttgcaga tgtcgacgtt gtaattgcag ccattgcagc
     2341 acggtaaata gattgcttac ttctcccgtt tgcggatcga tatagcgaca gtaacgcagg
     2401 tatgcagcgg caaaaagttc ctccagcgtg gcagaaccgc gtcgggcaga taacaaagcg
     2461 gactgcggat ggcgatcgtc ggttaagccc cagcctgcat accagggctg gccgaagcat
     2521 gtcaccggtt ttcctgccag caaggcttca aagccgtact gggaggtcac gacgtaaacc
     2581 cgggaaacgt gtcgcaacag cgactgcggg ctgacattct cggcaattaa acgtactcgt
     2641 tgcgtggcgc gcagagcggc gaaataacct gttttctttc cttccaggac atccggatgc
     2701 accttcaccc aaatttcggc ttgaggattt tccgccatcg cggcttccag catggcagca
     2761 aactcatgcg ggccagcatt gccatacgtc actgacatat cattaaatgt ctgatcgaca
     2821 accagaacga tgtctgaacg ttctgactca tcagccacaa acgcaggtgc caggttatat
     2881 ttcgacaaat ccccggtcac gatggtgtgc atcgcttctc tggcctggct tatcagagct
     2941 gtatttccgg ctttatcttg taccagtttc tccagtgctg aaggcttgct ggcatcgtag
     3001 taaatgcaac aatcatccac caccagagaa agcggcggct cgccattgac gccaagatcc
     3061 agcgaacgca caaatccatc ttccagacga atgacgggtt ttcccgctgc tttggcgatg
     3121 gcgactggtt tcgccgcgct gggacgatgt ccccacacgg cgatagcatc aacttcttgt
     3181 ggaacagggc gcagcagaga aagtttctgg cacggttgcg ccagaaatat ctccagatgc
     3241 ggaatacgcc agatgccagg cgagtaaatg ccaatcatgc gttttcagcc agttcctgtg
     3301 ccatcagggc gcgcactttt tccaggcatg ctggggtgtc gacgcccgga ccggttgcgg
     3361 caacctcaaa tgtgcggatg ttgatccccg cgttcatcaa ccttagctgc tccagtgatt
     3421 ccgcctgctc cggcatggac tccggtaact ggctgtagtt ttgcagcaca tcgcgacgat
     3481 aagcgtaaat accgacgtgt ttcaggtagc gcgctttttc agcattacgc ggatacggaa
     3541 tcggtgagcg gctgaaataa agcgcatcct ggcgggtatt cacaaccact tttaccgtgc
     3601 ttggctcagc cgcttctgcg gcagaaatcg cgtggcatag cgttgccacc ggcaacgcgg
     3661 gatcgtcacg cattccttgt agcagcgttt ctacatcccg cgggcgaatc attggttcgt
     3721 cgccctgcag gttaatgtag atatctgcct cgactttatg catcacctcg accagccgat
     3781 cggtgccgga ttcatgatcg ttgcgcgtca tgatggcttt cccgccaaac gcctgtacgg
     3841 cctgttcaac acgcggatcg tctgttgcca cccaaacttc cgcaacgccc gccacctgta
     3901 acgcacgctc gtaaacatgc tggatcatcg gtttaccaac aatatcgagc agtggcttac
     3961 ccggcaggcg cgaggagcca tagcgagccg gaatgacaat aactgctttg ctcatttcaa
     4021 ccccttacaa agacagaatc acttttgcac ccaccgccag ctgatagagg atggtggaaa
     4081 taccacgggt aacttcaatg tttttcgatt catatttcgg cagaaccata atctcatcgc
     4141 caggcttgag tgaatctaca tcttcagcgt tgactgccgc accgttctga cgaatgacga
     4201 taattctggc gttacccgat ttttgcgtca ggccaccgca tttctcgatg taatcctcgg
     4261 tggtcatccc tttctgccag ctcaccgcgt tcgggaacag cacctcgcca tgaaccataa
     4321 ccagcgatgt tttctccgga atattgatga cgtcgccatc ttcaagcaga acagaatcaa
     4381 tattggattc gttgaggatc acttcacctt tcggaaccac ggtgcgtgct ttcgccacaa
     4441 agcggctgat cagttgtgct tcctgcattc gcaggctggc ttcttctttg gtggatgact
     4501 gggcagaaag tgaggcttcc tccagctttt gcagcgagag attcagcatc tctttctgac
     4561 gctgagccac tgatgggcga taaagctgaa ctgcgttcat ctgcgacatg ctgttcgggc
     4621 ggactttttc cagaaccgca cgcatagtgg aaccataagg caataccatg gcatgttcac
     4681 cggagtgtgc gccttcaacc cgcacctgaa tggtgccggc atagcggtca gtgctcacga
     4741 ttaaggtatc gccattttgc aacatacggc ctggcgcaga actgatcgga tagtattcgc
     4801 tgcgtttttg cagcccctgt ttacgcataa tcgtaatgtg agtcgcgcca ggcttagggc
     4861 gcgcccagct caacgcttcc gttacgggaa tgctgctttc gcggaactca aagtcgtagc
     4921 tgttaaagac atcgccctga acgctgaaag tatgctgacg tggcccgacg atgatggtgt
     4981 caccatcggc gaactgcgaa agtcccagtt tgccgttcag caggaagtcg tacaggttga
     5041 cgttggagcg cacgcggtta ccgcgcttga ccacaatatc aacgtaactt ccgcgctctg
     5101 gatcaacgcc gccagccttg atcagataat tgagtaacga atcagacgtc acaccgccat
     5161 acagaccagg attacgcaca aatccggtca cgtacacttt tactggctgc gcctgtaata
     5221 aggaggcgta gacgttgacg ttggactggt atacttcctt cactttggat gtgaccaagg
     5281 catttagctg actattactg acgccagcaa ctttcaccgg accaacgttc ggcaggaaaa
     5341 tattaccttt gggatcaacc tgtaacgcac catcaaaggt gaacgcaccc cacaagcgaa
     5401 cctgaatgct atcacccgga ttcagaatat agtcagggtt gaatcctacc gtcgcaccgc
     5461 tatccgcgct ggtgccgttg aaaagttgag caccaaacat acggctcatt accaccggcg
     5521 gtgcgggcgg cggggtattg tcgaagccgc tcatgttttg cgtatccgac ttctgtccgt
     5581 tcagaatacc ggtaagcggc gcggctcctg tcaggtttgg gtcagcgtta atatcaatgg
     5641 tcgcgctggc ctgcgccgcg tgacaggcgg caatcagtaa aattgattta aataatttca
     5701 tcacaaactc attcagcgac agcgttagtc tcggtgatct tcaataacag ccagcaacag
     5761 tttcagggtg ccgaacagca ggcagcacac cagtaaccag caggcgatca aataagggat
     5821 atttggaaaa gacgattcct gcggcaactg tggcgaactg atcactgaca gcaccttgag
     5881 cttacgagcc gcttctacac gggtcttttc aatggaggtc agggtcagtt tgtacagctc
     5941 ggtgttgaac tctacttttg atttgatttc ttcaaaatcc actgccatac ggtttagctt
     6001 gtcaccctgt ggcgcagtga ttttgctttt ttcttcgtca atttgtgcct gcaatgactg
     6061 aatcgcatta cgcgcactca caacttgcgg ggcgtcctca cgcagatacg tcagcaagtt
     6121 ccgcaggtcc gcttccatct ggatcttctg gcccatcagc gtattcacta acgtgctcgc
     6181 cgcctgtgcc tgtgcctgtg gatccagaac gttgttgttg tcctgataag agagcaattc
     6241 cgctttgctg gcgtccagac gctggcgtgc cttttccatc tccgtttctg caaaggcaag
     6301 ctggtcacgc gcgatgcgat gtgacatctc attgataaag cgctctgact ctttcagcac
     6361 ggtttggtta aacttaagcg caaactccgg gctaaagccc tgcgtctgaa tattcagtaa
     6421 tccggtttta tcgtcatacg agacgttgat acggtccttg tagtacttca ggaagccttc
     6481 tgcggtttca tccttgctaa gatgattaag aaaatcgagc ccgctgtggc taaacgcttc
     6541 acgaaaattt agttgcttat ccagcgccgc cagcatatcc ggcgagttga tgtactcttt
     6601 cagatacaac gcatcttctg cggaactggg gttagaggca cccagaagca gaccaaaatt
     6661 caggctgccg ctgtttaaat catccgagcg tttaatggcg actttcgact cgctcatata
     6721 gcgaggctgg ctgaagatag ccagatagat cagcagcacc gccatcggtg ccagaatgat
     6781 gattttcgcc aggtgttttt ggatatctgc cagtgagatg gcagacagac gagcacgcat
     6841 ccaggatacg gcagacttca cttttatcaa catgtaacga ttatcaaagt ttcagtgggg
     6901 cgcaaactca atgagagact aacctctcgc accccgttgc ttaattagtc gaaaatgcgc
     6961 acaaggccag tgactttatt tgccttgttg gtcaccaata acgttgagac gcggtgcttt
     7021 tgcatttttt cttccgcttc aatgatcatg gtgtcttccg gtagcgtcag cggttcacgt
     7081 gtcatcatct gcgcagccgt ggcggatgtc agagaatcct ctttttccat aaagcgacgc
     7141 aggtcaccgt cggtgataat gcccgctagc ccaccttctg cgtcttctac catcaccatt
     7201 ccctggcatc cgctggtgat acgttgaatc acggttttaa atgacgcatc cagctgtacc
     7261 gcaggaacat catgctgcat gacatcagca acgcgggtca gcaggcgacg acctaatgaa
     7321 ccgcccgggt gatagcgcgc aaaatcattc ggcataaatt tgcgttggtg gatcatggca
     7381 atcgccagcg catcgccgat cgccatcgtc agcgtggtag acgttgttgg tgcaagatta
     7441 ttcgggcagg tttcattcgc catgtggagt tccagcacgg catcagcatt tttcgccagc
     7501 gtggaatttc cattattggt aatggcgata attcggttgc cgaaattttt cagtgaagga
     7561 actagcttga ggatttcatc cgtttcaccg ctggcagaaa taaggatcag aagatcgtaa
     7621 ggcgtaatca tgcccagatc gccatggaaa gcttctgcag gatgaataaa gaaactaggc
     7681 gtacccgtag aggccagcgt cgctgacatt ttacgaccga catgccctga tttacccatt
     7741 cccgaaagaa taacgtgccc tttacagttc attatcaaat taaggacacg ctggtactgc
     7801 ccggaatcca gttgtttaga caagttttgt aatgctgcgc tttgttctgc cagagtctgg
     7861 cgaacagagg taattagata tggatcgata gtactgctct ggtcatcagg taaatgtctt
     7921 tcagacatat cagctccttt gcacggaaat aatgccacag tcacaacaaa cccgaaccca
     7981 ctataattta tttatgctaa atcaatgggt tgtaacaaaa tttttaatga atataaaacc
     8041 atggtcagtc catgcttata tgcaggactt atcaccttct tattaagtcg caatgtctca
     8101 tggaggtgcg aagacgctgc aatattacag gcgagaaagg gaaccaaatt ttgcccacct
     8161 atttaacaca ctcctacatt atgaacaagg aatttaggat ttttatcatt tgttaaaatg
     8221 tttcctactt gactattaat accaaaacaa tttatcaatt gattatttcc ttgtaaaaaa
     8281 agaacgtatg actatgttat taataaataa aacacgcaaa taatggtgat gttgttttgt
     8341 gattaattat ttaaattcgg cataataaac aggttgataa tttctatgta aagaagagga
     8401 aaataataaa attttagcgg tgactattga atgatataat agttgtagtg ttgattattt
     8461 ctggtaatga atgcggaatt aaatctggcc ggattgtatt tttgctatat ctatttttca
     8521 ggagattatt attaaataga aaaataacaa tggtgattat ctccggttga gctggagtca
     8581 cgtatgccag cgagtgcttt cttccgggcc ttccttcact tcagagaaag agcctatgga
     8641 aaagaggcaa tcatcaggct ctttttgagt catatgcgcc gataatcaac tgtcttgaac
     8701 gtaaaaatta tggagcaaca tgatgctacg attcatttca ctcttcgttc tttctgagca
     8761 ttgcgttcag gatggtcagc aatttacgca tacagtcaac cagcgccact tttttggttt
     8821 ttccggctgc tggcagatgc atgtaaaacg cctctttcac cggattaaac caggttacca
     8881 caagcgctgc catgtgcagg gctgctcttg cctccgtacg cgcactggcg tcgttcggcc
     8941 agcagatatg tgtgggataa cagggatgtt atgtgaactg aactgtgttt tgttagcggg
     9001 ggatgtttat tgatgattcg ggagtgttta agacctgatg gcgttatgca cccaagttta
     9061 ttttatataa agatccaaaa gcaaaaaccc gccttgtggg cgggttctta agaattagtg
     9121 gtgcccggaa tcggaatgaa actgattgta taacaaattg ttttatatag attattttgt
     9181 atttgttgtt tttgaggcca ccaatgaggc ccccatgtgc aattcgaatt cttttgacgc
     9241 tataatccct cttttttgtg ctttgctgta atcatttggt ctggttcgat atgctgaatt
     9301 gtggaatcgt acttaacgcg tttgttagct ggtcagaaca cttagcgctg tttgtctgaa
     9361 actggaatag gcttcttccc agttaatctg tgtattacca aataccatcg gtttaacaaa
     9421 tcgttgaaag cgcaatttgt gtacaggata atcccggagt gcatccagcc ctttcttaag
     9481 ttcatcaact ggtgagctac aaaattgtgg gtactggtta ccatagctga atacatatct
     9541 gaacaaaatt tttcaataca ggaacattca cacctttttc cctgacaatg cagtagttgt
     9601 cgtaaatgtg acgtaccaga aactcatcat cctgttgttc gggattacga agatgtgctg
     9661 ctgttcttcg catcatggag atgagctttt cagcctgagt ggataaaatg gtggcacagg
     9721 ggaatgctgt tacaggtgta cctttacccg ttaactccgt gacaagggaa taaatatctc
     9781 tgctttccgg atgttccagc agagtgcttt ccatcaactc cagcttaata aatggacgaa
     9841 gacaggggac ttgtgcaaat gtctggggat aacgtaccga gatttcgtta taacgatact
     9901 catcacgtgt tatacgggcg ttttcattat ccaagctgaa aatgtcagaa ttatgaataa
     9961 catccgtgat tatttgcacg atttccttgc gaatttttct tctcttgtct ctgccatttt
    10021 gcataaagtt ctctgttggc acgagcttta tatcaatatc ttctgacatt ctgtttagcg
    10081 agatacctgc ttttgataat gcggtacctc ctgcaaacac gagagtatgt gtttctggtt
    10141 ttatttcttt taataatctt aaaagatcaa ccacaaaata atctttttcg acgatagcga
    10201 cagattcaat atccagtgca tcggcaacgt caggaaataa tgatgttaat tcaggcattg
    10261 attttacttt tccctactat taacattctt ttaaatcgag aaggtgtttt tatccccaga
    10321 gatacaggaa tttgtgtgga ctgactttta ttgtagcatt ccgttgctcc tgccagacgg
    10381 tatctgatat tcaggcgctc cagggcctct gtaattactg cagcagagcc cccaggcgct
    10441 gcgggcatga ttttcccagt gatgatgtta cgacgggctt tggtgtaaac accatagccc
    10501 actttcatca acttaccttc gtttaccagt gtacgaagag ctctgccaac ctgatcatag
    10561 ccagcgatat ccctgaaatc atcccgggtg aacacataac gttttgaacg gttcagtcgg
    10621 gactgaatac ggtcttttgt agtcatgttt cctccgaaaa attttcacaa tgatagcaaa
    10681 aatatgacat gtttaatagc ggggcaaggc cacattacct gtctgctaat acatttggat
    10741 agtgcctggc aattatgtca tttagcctgt caaccagttc tggtttcctg aacgtgatgt
    10801 gtgcggagcc cttcttaaag tatctgatgc tgaacatctc atcttcatag cacgctttgc
    10861 cctgaacgga gcggatgtga tcatccagcc gaatgatgat attttcccgg ctgtcgggga
    10921 tcggtttgcc gctgaacaga tgcagcattc tttccaggtc agcgagtcga tctgcctgtt
    10981 gcccggtgat aagatgcaat ccccatcggt cccatctcac cagattgttg acgataattt
    11041 tattgccaaa tttacagggg caattggttt tgtaattcca gctcagccct ctgaagaggt
    11101 tgatcacacc tcgctcaaac acgtcatcct tattctggtg cagttgttca aacgtactca
    11161 ggatattcgc ctcgctgatt tccggaaagt tatcgtactc cagtgagcgg taccatgtat
    11221 catgggcctg cgcatccatt aatgacagca tcccggaatg ttgcatcagg tcacgccaga
    11281 tttcgcgatc gagattgcgg gtgatggctt tcattgcggt ttccggtttc tccatgagcc
    11341 agcagccgca gcgaaaatcc tgtttcatcg cccagtccag ggcggtttta cctccaatac
    11401 tttctgtcag tactgagatt tctgccagtt gccggataag tgtgtcgatt tgcagcagcg
    11461 cactctttcg tacagccaga atgtggcgga tactggttga gcagataacg tccgtatgtc
    11521 cgttgaccag ttccgggcgg gagattgtga tatctgacat catcgttttt ccttttggtt
    11581 tataaacgaa aacgccagcc gtattcaggc tggcgtcagt ggaatgaagt ctggtgagta
    11641 agactcaccg gttctgttgc agaagctgca gttggcgcag ggtacggata tcttccctgg
    11701 cctgtttaat gcagggcagc agtgctgctg aatccgtttt atcctcatcg ttgtcgaaga
    11761 taatccctga ttcgcagtca atattgtcct gcagccacgc aatcagaata tacagcgctg
    11821 tttccgtggt taatgatttc atgttgtgaa tttccgggtt accagtcgaa agtgggtaaa
    11881 tccggcaggc attcagtgct ggcatccaga tgaatgagac tgacgccata acgtcgggta
    11941 agtgtgacaa ccagacggcg gaacgttttt gacagcccca ggcgtttaag ccgcagaacc
    12001 gggtatgacc acgcatcggt acgtaacaga tatccgctac ctgtaaaatg aatccattct
    12061 gattcgccgg tgtcattcgt ctgatgcgac agcgagtaca gccaggcgtt gtctgtttcc
    12121 gtgatatgcg cggtactaca gcgtataccg ctcagggcag cagagggggg tatgctgtct
    12181 gttgaggtcc ggtcagattc atcaacaaca cgaagggagt agccattatc gcagaccacg
    12241 ttaatcagtt cggcaagctc aacaccatcg acgtcaacga caattcgccc catgttcagt
    12301 gcctgtacgt taacgctgtc agcttccagc gtcagggcca gtttcatcgt tttgcctccg
    12361 gatgcttgcc ctgggtaatg ttatttacca ttctgtaatt gttccgggtc atcaggccgg
    12421 tcgccctgcg agcccggaga atatcaatgc tgttgattaa ctgcgacggg gctcctgcgc
    12481 tgaatcccgg ctggtcggta cgtacctgcg cgtatttttc aacgagaaag ttcaccgcgt
    12541 cacacagtga aatccctgcc tcaatatgct gctcaatcac acgttcatca gcgaacggtg
    12601 tgtcattcag cgtgaggcca tagtgctggt ccagcagtcg ggtgagcagt gtctgccaga
    12661 tggtgacggg agacgggcag cgcgatgccg cccgtacgtg tgtgtcgggt aatgttttca
    12721 tactgaagat tttcctgata tgcagatata aaaatggaaa agtggcgtgg tgaaaacacc
    12781 aggccgtagc agaaggctat tctggagagt taatttttca tttcgggcgt cggataaaca
    12841 gccagataaa cgtaatcaca ggagcccagg gtatcggctt cgcaggtcag tcctttcgca
    12901 tacagtgtga cggtatgctg atggcgggga ttcagttcac cgctggtgag catgagttcc
    12961 ggttgtttca tcagcagcgg aaaggcctgg tccggatggt acgcatccgc atcgctgaac
    13021 cggcctctga taccggcgcg gtcggcaagg taatgcaacc ggttaccctc ctgcaccaga
    13081 caggccccga aacagggcgt cacggtgcag ggcagccccc accaggggag gtctttgttg
    13141 tcgtcgggaa gcgttgttcc ggggagtgtg tccgacatga taaaatcctc acagaaaatc
    13201 ggtgaatgat agtttaacga tgacgggtca gccggcgcgc agaccggctt cggtgaaggt
    13261 atattcgttg atgagaaggg cctcatccac agcggtgtct gaggtcagcc agtcgtactt
    13321 gttttccagc tggcggtaca gccagaaggc caggtcgcgc agggcttcgc tgacagcggc
    13381 ttccgcatcg gttgtcattg cctgaccagt cggactgttc cgggtgacgg tgatatccat
    13441 gctgtacgga tggcagtaac gtccccggtg actgatttca gcctgaagct gccagaagtt
    13501 acgtttctgc accgcctgca gggtatccgc gatacgatga agctcacggt cctgaggggc
    13561 atattccctg attttccggg gtgtcgctgg ctgccagtgc cagcgccctt caaaacaggc
    13621 tccgtccccc tggctgcaga atccgctgaa ccagatgcac ggctcttcca taaacctgcc
    13681 attgctgagc cggaaaacgc gctggcggag gtcaatcccg aaaatgccac agacctccct
    13741 gaagtcttca tacacgtttt cataccagtt gctgtcagca tgatgctgac ggtaccagtc
    13801 gcgggctttt ccccgtgccg ggcaggaaag ttcatccagc gtatacactg tgatggtgat
    13861 aatgctgctc atctgaatgc ccgtcctgat tcagttcagg gtgacgctca tcagccggac
    13921 atacgggcca aaactgtcct tacgacgttc agcaaacacg gccaacacac cgggaatatc
    13981 ctgcacttca cgaccggtat acgcttcagt gctgccgtgc cagcggtatt tgccggtaca
    14041 gaacgggaaa agacgggatg tcggatgttg ttggtgaata cgcatggctt caccacgagt
    14101 gataattttc ataatgggat acctctgaag acagaagata aaagtgaaaa caggtgtgat
    14161 gtggttgtga cgggttaaag cagaccatgt tcggcaaagg agaaaacctg gttgccaccg
    14221 actatcagat ggtccggcac ccggatatcc accaggccca gtgcctgtac cagacgttcg
    14281 gtgataagcc ggtctgcctt actgggtgtg acttcaccgg acgggtgatt gtgcgccagt
    14341 accacggcag cggcattgtg gtacagggcg cgtttaatca cttcccgggg atggacttcc
    14401 gtgcggttga tggtgccggt gaagagggtt tcaccggcaa tcagctgatt ctggttattc
    14461 agatacagca cccggaactc ttcacgctcc agtcccgcca tgttcagaat cagccattcc
    14521 cgtgccgcac gggtggaggt gaaggccaca ccgggttcat gaagatggcg gtccagggtt
    14581 ttcagagccc gcagaatgag actgcgctcg ccgggcgtca tttctccggg cagaaaggaa
    14641 agctgctgca ttgtccctgc ctccattcag tcgatgatgc gcataatggc gctgcattcc
    14701 ggatgctgca gggcgtaatc ccgcagccgg taataatgga ccgtcatggc ataacactcc
    14761 gtacgacagg cgtgatgact gtacgtcatc agacaggcag caatgccagc ggcttccggg
    14821 ctcatttcag cgcggttgcc gttcatggca ttgaacagta cccatgtttc gtcatcatcg
    14881 tcatccggtt cgggggccat aaatgccccg ccgttgttca gggtgtacag attccagata
    14941 ccaccgcagt agtcttcgca cagacggtcc atccagccga aaacacgggg ctccagggcc
    15001 acccactgtg gaatgaggcc aaaatgctgc ggccagaagc tgatgcgctg ttcatcaggg
    15061 actatggtgg caaccaactg aggctggtca ttccctgatg cagcggttac ggaaacagaa
    15121 gatgtggtgg aattatgtga aatggttttc atgaaatgac tccttaaagg acaaataaat
    15181 gcgtggtttt cagggtaatg gctgaatcag cgcaggctct ccagcagggt ttccgccatc
    15241 acccacaatg cgcggttgag cttaatgtca gtgtcaatgc tgtgaatggc acgggtatgg
    15301 atacgttttc ctttagcgct gcgacctgaa attccgcctt tcagcatatt ctcctgaatg
    15361 gtctgataag cactccacag gtccttaccg taatcctccc ggcgtcgtgg cgtcagaatg
    15421 tcggcggtgg tgacgggctg atgttcgtca ccataacggt aagtcagtgc cgcctgtgcc
    15481 agcgcctggc gtgccggtgg cggcagaatc agcgactgca tggcatcacg cttttcctca
    15541 atccggtcaa acacgcccac tacctcgtaa gccccttcaa tgactctgtc caccacattt
    15601 ccccggtgcg gaacacgcac ttcccccaga gactgaccac agacgcaccc gttctggcag
    15661 acgaacctga agtaacccgg cagcatctgg tagctggagg taccgtcatg agagttgagc
    15721 agaataattt cagggacatg ttctccgttt atctctccgg cccgccgcag acgcagcatg
    15781 tgttttgtgt atccccggcg gcccgggtcg cgcacacggg tctggcaggc gaagaatggc
    15841 tgaaagcctt cccgctgcag gctttccagt acggtgatgg tggggatgta cgtatagttc
    15901 tggcttcggg acgtgtgttt atcttccccg aaaatccccg gcacatagtg catcagttct
    15961 tcgtgtgtca gcggacggtc acggcgtatc tggttcgcat aaccaaaacg actggctagt
    16021 cgcataattt gctccttatc ggtggttaag atttactggt gtaataaatg aaaaaagccg
    16081 cgtctcccgg agaagacgcg gcctgatgga tgaaatcaat gaggtttatt gtctgagaag
    16141 ccctccactg gcgagccacg cattaagctg ttttccggca tcagcttcag agttccggca
    16201 gcgccagcgt cgctgacctt ccgcgttgcg gataacccga cggaaatgca ttcccgggtc
    16261 atcctggata aacacattgc ggtaagcggt tatgacagca accgcctgcc cgtatgagaa
    16321 agatccttca gccaggacat actctgtgta acccagcata tctgttttct cctgataaat
    16381 aaaaagcctc tgccacgcgt tgtgacagag gctgaagcat gaaactgact tcagggatca
    16441 gttaacgttt tttccggaaa cggtaatcag cagtggatgg tagtcctggg gatcgaaaac
    16501 cgataacggc agactgacac gatggccgtt actttcttca gttgctttaa tgatttcggt
    16561 tgtggcgaca ttttccacgc actccgtttc cagaaatgcg tctgtggttc gcgtggcatt
    16621 actgtcacca aaggcttccg tttccatttt tctggtcacc agcgtctgac catatttgtc
    16681 tttgagttgc agagtgatgg tgagggggcc aaatccttca tcgtttccgc cattatccag
    16741 ccggaactgg taagcacaaa tatttcccgg gagccatatc gtatctgtat tgcgtatact
    16801 gatgtaacgt tgatcctgtg cccggagtgg ggcagaccac gttaacccca gaatgaaggc
    16861 ggtaatcatg caggttttga acaggtgaat catggtattt acctctctga gtcatgacga
    16921 tgacactgac aaatcaggtg ataaaacgta aaaggcgcag aatagccgtt atgccggtaa
    16981 ctccgggggt aatgtttctt ccagtcggtt aaccatattg ccgagatggg atgcatcata
    17041 ttccatgacg gggcgttgcc tgatgatact gaccaccagt ggtttgatta acatgttggt
    17101 cgcggcccgt tgttgtatac cggcggcgaa aatgatctcc agagcattct gatcgataac
    17161 acgggccaga ttcgcgttca gattttcaat ctcatgtccg gtcagcagga aactgccggc
    17221 aagccatgtc atctgctcct gaatcattgc cagaattttg acgcgatctt cttcaaccag
    17281 cgctccggca atttttcctg atacagcgga ggcaatcatt ccccccagaa caccgccaac
    17341 cacacgccct gtcagtgcac caaatggtcc cagtggactg aacaatatcc cgcccgccac
    17401 tgacccgaca gcaccacctg ccacacagga agatgccacg gcaagattcc tgatgaactg
    17461 cgcaccggag atccgtcccc gcaacatttt gatcatgtca gggccggttg tgacagctac
    17521 cagtgccaga gatgtcacca gcgaaccctt catcactttg ttcagggcac tgatatttcc
    17581 tgcaccggtc cccttctgaa gcgcctgccg gacagtcggg ctggccgtcg aaaaatcaat
    17641 atgcttcagc ataccctgaa caacactgag ccggtgaagt tgctgggttg tgacgtagac
    17701 agccagtgtg cgggtgaagg tttttcctgc ctggacagca gctgtctgca gggcagcatc
    17761 gcgatcgccg gtgctgagcc agaagaccga tgccgtcagg gcaaaactga tccctccggc
    17821 cgccagactg acaaccgacc cctcggcaat atcataagtg accgattcga tggtcccgaa
    17881 ccgggtgata ttacgggcct gggtataagt cagatgtccc cgacgaatca gccgggacgc
    17941 ttctgcggga tcggttacac cgggtacttt accttcgcgg atcttattct tcatggtttc
    18001 cacagcgccg gcatactgat cacgggggac ttccagttgc atgggaccat gatttcccat
    18061 gtaacgatac tgtccgttct gtccgtcgaa tgccgcactg ttaatgccag cgaatgtggc
    18121 gttgaatatc cgttgcgccg gtccgggtcc cgatcatgat gatcgggacc acaaagaggc
    18181 gatggttctg tcagaaggtc acattcagcg tggcctgacc gttatagcct tcagcgctgt
    18241 tgccgctgac actgtgggca taaccggcct gaacgcccag ggtgatattt tcccggacac
    18301 gggcttccag tccggcctgc aggtccagtg acgtgccatt ccgggacggt gagaacgtca
    18361 tgttactgcc ggctgcggct gtacccatgc tcatgtctcc ccgggagctg aaggtgcgga
    18421 taacagaagg ctgtacccac cagttcacag gcagttcact cacaccgtgt tttgtactgt
    18481 cgcgcagggt gtcacgggat gaggtgcctt caccaaaggt catatcgttg tggctgccca
    18541 gacggaaacc ggcacgcaca tgttgtgcac tgccatgccc gaacttcaca taaccggcgt
    18601 tatcctggcc gtcatccagg gaaagtccct gccaggtata ctgcagttgt ggctccagca
    18661 tcaggttgtc agtgatactg aatggcagac cggtttccag tgagccctgc cagccccggc
    18721 cccgggcgcg gaagtcgtta ttgtccgatg acgctttcat gctgtggcgg gttccctgtg
    18781 ccacaatgtc agcccacagg ccggaggacg tgtgtaccag attcaggtat ccgcccaggc
    18841 tgccggcatc atcccggacc gtgccggcac gggagccgtc atcatcctta acatcaacgg
    18901 aagaatggcc tgcagcacca tacactcctg tcgtcagtga cataccggca acctctgttc
    18961 tgagcaggtc accctccaga cggacgaagc catagctgcc gctgctttcc ggcgtggcac
    19021 cacggacaat accgccgttg ttatcgtgac cgagatggcc gccctgaatg ctgagacgga
    19081 cgctgttatt ttcaccgttt acaccggtct gatggctgcg ggagcctgcc agaatccggt
    19141 catagtccat tgcctgtgtc agcatggagg catacagggg gacttcagca cgataagcat
    19201 tttcactgcg cagataccag ctctcatcac tgtcccggtt gagggtgtag ttaaaggccc
    19261 cggcctgcaa catattcccc tggacaaaag ccccttcctc cgtggtggca ccgttaatgg
    19321 cctcaaccac ctgaataccc ttaccggtgg tcgccagccc cgtaccactg ttgccggcgt
    19381 tcaccagatt caggatggtt tttccggttg ccctgccacc gtcaatgacc agtctgtcag
    19441 cattgttctg cgccatatcc gggcgtacac gcaggctgat ggtgccattc tgcccgttca
    19501 ggtttttcac ctgcagagtt gtcggaacga acttccctgt gcgggcggag gtgaaatgaa
    19561 tctgtccggc atggctgagg tcatccacca ccgactgaac cgtggcgtta tcggggatat
    19621 tccaggtggc accggatgtc agggtgacat tcgtggggtc aatggcaccg ttcagcactg
    19681 tgctgccggt cagcttcagg gctgtaccgc gctgagcaat gacatccgtg gtgacggtac
    19741 tgtcgttcag cgtcagcgtg ccttcattca ggttgacggc tttctgggtg agtgtggtgt
    19801 tgctgacagt gagtgtgcca cttcctgatt tttccacgct gccgttaccg gtaagagcgc
    19861 ctccctgcag gagtgcatcg ccttcacgga tggtcagggt atcgttgttc accgtcttcc
    19921 cggaaagggt aagtgtggcg ccgttattca gcgtggtggt gcccgccagt gtgccgcccc
    19981 tggcggtgaa cagtccgcca tttaccgtgg tatccgtggc cgtatcaccg gcgttcagcg
    20041 tgaatgaact gcctttttcc agcatcaggg catccgcctg accgcctccg atactgaatg
    20101 cctttccgtc gctccgggta ccactgacag cggcaccgga atcggccagc agtacaccgc
    20161 cattccccat ggatacggtg gtggcggcac caccgttgcg gatatccagc gttccgccat
    20221 catccacacg ggtattagtg gctgtgtgtc cgctcagcac atccagacgt ccgccatttt
    20281 ccagtacgac attatcagcc ttacccgcca caacggagaa tgctcccagg cggtttgtgc
    20341 cggtgacggt tgcagctgta ctggtaacca gtgcaccgcc cgtgttctgg gtgacatcag
    20401 acgctttacc gccggcattc acctgcagct ttcctttctg gttgatggtg gtatgcgcgg
    20461 cagttcctcc ttccttaatc acctgccagc catcacggtt tatcagcgtc tctgttgccg
    20521 tgccaccgtt gtgtacatac tggttacccc cctccagtcg ggtgttatgt gcctctccgt
    20581 gtaccgtctg gtcaccaccg gcgtaaatga gggtgtcccg tgccatcccc gaagaccaga
    20641 taacctgccg gccattttta ttgatggtgg tggattcagc cgtccctccg accatctgac
    20701 cgctggacac attttcagac tccggaccac cttctgcacc ggtgttgacg atggttccgg
    20761 ttgccagtcc gccatgtttt atggtctggt aaccatcctg gttaataatt gtaccggcag
    20821 ctttccctcc cccgtgtacc cactgctcac ctctgttatc cagcgtggtg ttcaccgcca
    20881 gtccgttaag gctctgccct ccgccatcac gaataaccgt atcactggca gttcctcctg
    20941 cctgcacaat ctgacgacca tttgcggtga cagtggtgtt tctgcctgtg ccacccgctt
    21001 ttatccattg cccgccggtg ttttcgtcac tgtccggccc cagctcaagc ccggtactga
    21061 cagtcacgcc atcagctgtt ccggatacaa actggttgtc atggtttacc agtgttccgc
    21121 cattcactgt ttcacacggg tgcacaacga tgtcagcagc cagcaccggg agtgacgtga
    21181 ccgcggcaag agacagtgcc accgccacac cgccacgttt accccgtgcg cgggccagtt
    21241 cggaggcaac cacgaaagcg cccgtaatgt gattccatac cagcctgtag caggtattca
    21301 gatgtcgttt catcagcatt tccttaatca gagtgagggt gaataaaaaa gccggtatcc
    21361 acagatgtgg ataccggcag gtaaagggtt acagtgccgg aggtccggct gacggaagtt
    21421 tctgacgtgt ggctctgttg ttccctgaat ctcatgtctg tgtgtatctg cgcacgttgc
    21481 taacaggagt tattattagc ataacgatcg atattaacga tcggtaaaat gggtattgat
    21541 cgttttattc ttttatcaag ctattgcacg gacaagagag acagtaacga aaacagcgct
    21601 tttgtgagca tacttagagg cagggaggac atcatccaca acaggttcag aagaagatcc
    21661 agttccatac cgcgcgggca acagagacca ctgtgtcacg gacggcacgc agaaccgtgc
    21721 gtgcaacaga ggcaacacag acgctctccg ctgtgtcaaa tatccggtcc accgcaccgg
    21781 taaactgctc acgggcctga gcgcggacag attccgtgcg cagctcgtcc tgcaggcggg
    21841 tcatcagggg actggcggca tggtcgggaa gcgctgtcat gagcgcactg accagcgtat
    21901 ccacttccca gccggtgcgg gccgatacgg ccacaaccgg atgtacaggc cggaacagac
    21961 ggaataccgc ctccgttttt tcgcgaatgt tctgtgcctg tgcgggagag ggctgaatgc
    22021 cggccatatc ccattcatgg cagggctccg ttttgtcggc ctgtgtcacc acaaacagca
    22081 cctgctgatg tccgcactgc aggatgtgtc gccagaaata ctcatccaca gacagggccc
    22141 ggtcatcggc tttaatcagc cacagcacca ggtccagttc aggcagaatg tcacggtaca
    22201 gggcttcata ctctgcatcc ctgtcccggc tctcgcccac cccgggcagg tcagtgataa
    22261 ccatgctgta accgtgacca ctcagacgga agcgctgcac ttcccgggtg ccggcgtgaa
    22321 catcactgac cggtgtgacc tccccctgaa acagggcatt acagagtgaa gatttaccgg
    22381 ccccgctttt acccataatg ccaatcacgg gctcgtgacg ggtgagtttg cgcagatgtt
    22441 ccaggatgtg acgggaaagc gagtaaggca gggaggagag cggtttttca attgcctcaa
    22501 tggcatcaga cggattcata catgtattcc cggtgaaaaa agacaaaacc ccgcacaccg
    22561 gaaaggtggc gggggatcca cggagataat atctgtctga aattgtttgg aatcgatggg
    22621 gatgttgcgt attaacatga aggagggcag gagttatccg ttattgggtg atatccttcc
    22681 atgaaaatac gcggttattg ttaaacagca ggctgattac tccgtaaagg agaaaaatat
    22741 tcatcttgca gcctgattat caggtgtgtt tatgtttact gaggtgagta tttttcagta
    22801 tattgtcggg gcagtcagtg ggagatatta aatttacgtt tagagttatc ttgcttctgc
    22861 tgtgtatttt tataagagtg cgcacgtaat gatatctgtt gataccatgt tgttaagtgt
    22921 ttcccttccg ggtcatgcgt acttgcaaaa tggcatctga atcgatcacg gtttggccaa
    22981 accgtgatcg aatagatagg aatacgcacg taatgattaa atgcttttgt tacaccattc
    23041 ttccggcatg aatatttatc cagttccctt ttttatttgt gtagtgatac tgtcggaata
    23101 gcgttcagta atgtgaagtg tcctgtaaaa aaactttaat aaatgtgtca tcctggtcag
    23161 gaaatatctg ctgagatatt attagttggt ggtgttttta ctgagtaata gctggctttt
    23221 aattcctgaa ctgaaatact gtcgctcgtc agggtttaat taaaactgga tgatgatgtg
    23281 aaaatgaagg ctggtttttg tgtttgtcga agaagtgtta ttttaatcca ttctcatcat
    23341 tggctggcga ttatacagaa gtatttgaag aaaaaatgtt gcattttatc tgtgtcagca
    23401 gggaggaagt attttattga tgtatcagta ttaaatggtt tttgttattt ataaaaatgt
    23461 catcctgtcc atagaatatt gtactcagca ttcagtgcag gaactgtcat tttctttatt
    23521 ttattcttct tcaggagggc agttttctga aagcgttact ccggggaaac tgtttatgtt
    23581 tattcccggc aggaaacccg tacctgcaat accctggatg atgctttttg ctggtacgtt
    23641 gttgtgtgaa atttaatcaa cgtgtgtgtt ccggagagcg cccgtagacg cacagattca
    23701 ttctgacatt ctttagcgac aaaataccga atggttatta tttaatctga aaatcgacag
    23761 aaatttttat cctgtattga ttctgctgct atttttgcta ttagtagcaa tagttgcggt
    23821 actttatgtt ctgtgtgttg tgaggtcatt atgccatact ttcagtatcc tgatgagttt
    23881 cccctgagct cgctgcctcc actcattcgt gatgccgtta ttgaagctca gcaaatcacg
    23941 caggctcccc tggggcttgt ggcagcatct gccctgggcg ctgtttcact tgtctgccag
    24001 aatctgattg atgtctgcag actgaataca ctacgggggc cggtttctct tttcttactg
    24061 acgcttgctg agtccggaga acgaaaaacc gcagtggaca aattattaat ggagcccctg
    24121 taccagcagg agatgctgtt atattccaga cacaaaaatg aactgacgac atggaaaaat
    24181 aaggaagagc ttttaaaggc gcagaaaaaa gcattgttgt caaaactgaa taaagaactc
    24241 cgcaaaggcg cggatgagtc agaaacgctc agacaactgg aagcgcttca gaaaaacaga
    24301 ggggaaaaac ctgtaagata taaattcatt tttaatgatg ccacgactgc ggcaattaag
    24361 aatcagcttt gtggtaaatg gcgttcagtg ggtattatgt cagatgaagc cggtataata
    24421 tttgatgggt ataccctgtc tgagctgcct tttattaaca aaatgtggga tggctccgta
    24481 ttgtcggtgg acagaaagaa tgaacccgaa cagatgattg aaaatgccag aatgacatta
    24541 tccctcatgg tacaacccgg tctttttgac cgatatatgg agcgaaaagg ttctgttgcc
    24601 agggacagtg gttttcttgc ccgttgtcta atcagtaaac ctgccaccac gcaggggaaa
    24661 cgctttatta acggagctgt gaccccggga ggatcattaa cggcatttca tgaacgatta
    24721 atggagctgg ccagaggcag tattgaaaaa tccagtaagg atgaacgtta ttgtctgcat
    24781 ttttctcctg aagcgcaaaa aatatttatt gatcactata atgttctgga gcaggatttg
    24841 tctccttccg gacccttaag ccagtttcgg ggacatgttt caaaaaaaac agaaaacatt
    24901 gcgagaattg ctgcgttatt gcagtatttc agtcagggtg aagggaaaat ctctgccgat
    24961 atcatgacgt ctgctgtcgt aataagttcg tggtacacag atgaatataa aaaattattt
    25021 gcgttacctg atgaatctga actgcagctg caggacgccc gggagctgct cgactggctc
    25081 attgaggagt gccgcggaga atgcccgccc cgtgtcagga aaaattatat tctccagtgt
    25141 ggcccgggcc ggttccggaa caggaaaaag ctgaacgtcc tgctgaacat tcttgcatct
    25201 caactcaggc tctctgtcgt gcaggaagga aaaaccacct atgtcctgct ttccgaaata
    25261 aacaatatca cgctgcctga actgaatgcg tgctacagcc agaaactgat aagatggcat
    25321 gagcaatcct ttggcttata atgttccctg ttgctgagac ggattattca gtggtggtat
    25381 cgcagtatgc ccgtcacccc cgcttctgca tgagggtgac ggaggaaaag taagtgtgcg
    25441 gaggcccggg agcgttatga atcaacaggc gtataacagg tactcgtcaa tcatcagttc
    25501 cagctcgcgc ttttcccgtt tgcgcgccac agcccagttt tcaagctctg catgtgattt
    25561 atgctttaac tcttcagtcc agggctgcat ggagtgggca cacatcagat cataccagca
    25621 cagccatatc agcgtgtggt agagatcacg atcgtcgaaa cgccggagca ggctgttcag
    25681 cctgtttgcc agccggtttt cacccagacg atgtagctca ctgagtaaaa cgccgcccag
    25741 attaaaatgt gtaagcagca tgatttcatg ggtctgaatg ctggtcatta acccttcctg
    25801 aatggcagga atgaacggtg gtgttcccgg gttgacgacc tgatagagtc cctgtggtgc
    25861 cactgagatg atggtgcctt tttctggcag aaaaaagtgg gccagggtca ggcggtgata
    25921 accatgaaga tgcggagccc ccattccatg agcgacgata agcctcgtca cgtttgtcat
    25981 ccatttctga tgctggatga gcagcagctc acaccggttt tcaagttttt gcataatatt
    26041 ctctccttta gcgcgcagca aaatgcctcc gggggccgga tcatgccttt gctgcggttg
    26101 aacggataac ggtcaggaat tacggacggg actgtgtaat acgtgcctgc aaccaggctt
    26161 ccacttcact tttcagccat cgggagctac ggcccagttt gatgggggca ggaaaggcac
    26221 catccttgat gagcttgtaa aaccatttat cggtcaggcc ggtcagctga gtgataaacg
    26281 acatgtcgac catctggtca tccatcagtg aaactggggt attcatgaaa atgttcctcc
    26341 ggatgttgtt aatctcaacc ggcgttggtg atgaaaacaa cgcaccacct tccccggcat
    26401 aacaaccggg gaaaaacgta aaaaataatc gggaatgtga ccgtcaggag ataaacgggg
    26461 ggattgcggt ggctgagccg taccggtatg tcgggtgatt gttgcgaaac gatgcttccg
    26521 cacgcgcacg tgataaagga gggaggactt tcgtgagaca aggggaaaac tggcgttctg
    26581 ataattgcag agttgttttt gaaggcggtt gtggtgcatc agcccgtgac ctgtgggcag
    26641 gcgacaggta tcactggtgg gataagactg tctgattggt attataaata tataagagag
    26701 ctcaaacaca tgagttcata tatgtgaaat aaatctgtga gtgtgatcag cagaccagtc
    26761 tacccagtag caacagattg cgttgtactc acagggttat ccctgataac tggcgtataa
    26821 cctgcgtaca taaaacgtac ctgcaatgca cctgaacaga gtgcattaag catccgcctg
    26881 agcggtaaac gtatccgatc tggtgagtga cagtctgaga gcattctcag taatcgcccc
    26941 cttgtatcct ggaaattggt taagataaca gcgattagat ttggcaaggt gtatgcagcc
    27001 agcagcttaa catctcagct aactggctgg ttaccttcag gttgtcgcaa tggcatcgga
    27061 catccggtgt cggataacta aacgtagcgt taaggcgata ttgctgagag accggttaag
    27121 tggttgcacg ggagtaatga gtttggggag ggtaccagaa tgtcagtctg gtgcggtatg
    27181 ctggcagtat cacgttgatt acagcataaa gtaacgagag acgaatggaa gttaaaacca
    27241 gagcagttcc gtcgttgttc atcccgggag acgctggaaa aagtgatttc ccacacacgt
    27301 tataaactta cccctgcgga gctggaagcc tttaactctg cggtcgat
//
LOCUS       DAPOXO010000070        26841 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.070, whole genome shotgun sequence.
ACCESSION   DAPOXO010000070 DAPOXO010000000
VERSION     DAPOXO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26841
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.070"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(35..1894)
                     /gene="gss"
                     /locus_tag="ROH59_003503"
     CDS             complement(35..1894)
                     /gene="gss"
                     /locus_tag="ROH59_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HDX4805942.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHTPLPQGQQ
                     WTRELEMVVENGGYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDQTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK"
     gene            2099..2965
                     /gene="yghU"
                     /locus_tag="ROH59_003504"
     CDS             2099..2965
                     /gene="yghU"
                     /locus_tag="ROH59_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HDX4805943.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFASINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP
                     ALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGG
                     FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGN
                     VVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDAS
                     DFETNTEDKRQG"
     gene            complement(3035..3283)
                     /gene="hybG"
                     /locus_tag="ROH59_003505"
     CDS             complement(3035..3283)
                     /gene="hybG"
                     /locus_tag="ROH59_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HDX4805944.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(3296..3637)
                     /gene="hypA"
                     /locus_tag="ROH59_003506"
     CDS             complement(3296..3637)
                     /gene="hypA"
                     /locus_tag="ROH59_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDX4805945.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(3630..4118)
                     /gene="hybE"
                     /locus_tag="ROH59_003507"
     CDS             complement(3630..4118)
                     /gene="hybE"
                     /locus_tag="ROH59_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HDX4805946.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDSV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVANPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(4111..4605)
                     /locus_tag="ROH59_003508"
     CDS             complement(4111..4605)
                     /locus_tag="ROH59_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HDX4805947.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKNAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
                     ATHD"
     gene            complement(4605..6308)
                     /gene="hybC"
                     /locus_tag="ROH59_003509"
     CDS             complement(4605..6308)
                     /gene="hybC"
                     /locus_tag="ROH59_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HDX4805948.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(6305..7483)
                     /gene="hybB"
                     /locus_tag="ROH59_003510"
     CDS             complement(6305..7483)
                     /gene="hybB"
                     /locus_tag="ROH59_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HDX4805949.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLQRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(7473..8459)
                     /gene="hybA"
                     /locus_tag="ROH59_003511"
     CDS             complement(7473..8459)
                     /gene="hybA"
                     /locus_tag="ROH59_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HDX4805950.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINSPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(8462..9580)
                     /gene="hybO"
                     /locus_tag="ROH59_003512"
     CDS             complement(8462..9580)
                     /gene="hybO"
                     /locus_tag="ROH59_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HDX4805951.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMVESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(9769..10056)
                     /locus_tag="ROH59_003513"
     CDS             complement(9769..10056)
                     /locus_tag="ROH59_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HDX4805952.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(10175..11062)
                     /locus_tag="ROH59_003514"
     CDS             complement(10175..11062)
                     /locus_tag="ROH59_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDX4805953.1"
                     /translation="MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKYAVGGMTA
                     LALFDLLKSNYALATQVEFTDPEIVAEYITYPSPNGHGEVRGYLVKPAKMSGKTPAVV
                     VVHENRGLNPYIEDVTRRVAKAGYIALAPDGLSSVGGYPGNDDKGRELQQQVDPTKLM
                     NDFFAAIEFMQRYPQATGKVGISGFCYGGGVSNAAAVAYPELACAVPFYGRQAPTADV
                     AKIEAPLLLHYAELDSRINEGWPAYEAALKANNKVYEAYIYPGVNHGFHNDSTPRYDK
                     SAADLAWQRTLKWFDKYLS"
     gene            11219..12259
                     /gene="gpr"
                     /locus_tag="ROH59_003515"
     CDS             11219..12259
                     /gene="gpr"
                     /locus_tag="ROH59_003515"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HDX4805954.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTEELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(12299..12793)
                     /locus_tag="ROH59_003516"
     CDS             complement(12299..12793)
                     /locus_tag="ROH59_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HDX4805955.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            12984..13868
                     /gene="yghA"
                     /locus_tag="ROH59_003517"
     CDS             12984..13868
                     /gene="yghA"
                     /locus_tag="ROH59_003517"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDX4805956.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAVKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(13907..14332)
                     /gene="exbD"
                     /locus_tag="ROH59_003518"
     CDS             complement(13907..14332)
                     /gene="exbD"
                     /locus_tag="ROH59_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HDX4805957.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(14339..15073)
                     /gene="exbB"
                     /locus_tag="ROH59_003519"
     CDS             complement(14339..15073)
                     /gene="exbB"
                     /locus_tag="ROH59_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDX4805958.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            15325..16512
                     /gene="metC"
                     /locus_tag="ROH59_003520"
     CDS             15325..16512
                     /gene="metC"
                     /locus_tag="ROH59_003520"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HDX4805959.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFVEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
                     MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNDEELANYLDNFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGKIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            16652..17311
                     /locus_tag="ROH59_003521"
     CDS             16652..17311
                     /locus_tag="ROH59_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX4805960.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(17351..18250)
                     /gene="yqhC"
                     /locus_tag="ROH59_003522"
     CDS             complement(17351..18250)
                     /gene="yqhC"
                     /locus_tag="ROH59_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YqhC"
                     /protein_id="HDX4805961.1"
                     /translation="MKREEICRLLADKVNKLKNKENSLSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            18444..19607
                     /gene="yqhD"
                     /locus_tag="ROH59_003523"
     CDS             18444..19607
                     /gene="yqhD"
                     /locus_tag="ROH59_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDX4805962.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPSRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFF
                     EQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            19712..20539
                     /gene="dkgA"
                     /locus_tag="ROH59_003524"
     CDS             19712..20539
                     /gene="dkgA"
                     /locus_tag="ROH59_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HDX4805963.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRS
                     IDTAAAYKNEEGVGKALKNASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIVENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
     gene            20739..21665
                     /locus_tag="ROH59_003525"
     CDS             20739..21665
                     /locus_tag="ROH59_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HDX4805964.1"
                     /translation="MKIILLFLAALASFTVHAQPPSQTVEQTVRHIYQNYKSDATAPY
                     FGETGERAITSARIQQALILNDNLTLPGNIGWLDYDPVCDCQDFGNLVLESVAITQTD
                     ADHADAAVRFRIFQDDKEKTSQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLA
                     TIASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDM
                     QIERQFIYDNPICFGEESLFSRVDEIRVLEKTTDSARIHVRFTLTNGNNEEQELILQR
                     REGKWEIADFIRPNSGSLLKQIEAKTAARLKQ"
     gene            21716..21973
                     /gene="yqhH"
                     /locus_tag="ROH59_003526"
     CDS             21716..21973
                     /gene="yqhH"
                     /locus_tag="ROH59_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HDX4805965.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKVNQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(22015..24234)
                     /locus_tag="ROH59_003527"
     CDS             complement(22015..24234)
                     /locus_tag="ROH59_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDX4805966.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKS
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICSHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRLQNAGAKKRPKAAVGR"
     gene            24486..25235
                     /locus_tag="ROH59_003528"
     CDS             24486..25235
                     /locus_tag="ROH59_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDX4805967.1"
                     /translation="MEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNT
                     SRTTIREAIIMLELKGVLNVKQGSGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVI
                     ESNITGFAASQISFNELQELKKIISLQENAIAAESDRFEDLDHRFHSIIAEATQNRVL
                     IKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREAS
                     WRHLENSKNELIKIFKQDASISDFDDFFFAR"
     gene            25558..>26841
                     /locus_tag="ROH59_003529"
     CDS             25558..>26841
                     /locus_tag="ROH59_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDX4805968.1"
                     /translation="MSGNESIAAAHYDQVTTWPRDGLQADIVHIGFGAFHRGHQAVYT
                     DLTNQLSDTRWGIFEINLFGDAQLIENLNAQNGLFSVVETSASQSTSRLVRSVAGGIH
                     TPRDGIAAAIHKLAEPQVKIVSLTITEKGYCLDPQTRSLDLTNGLIQHDLQNPDAPLS
                     AIGVIVCALQQRKAAGLAAFSVLSCDNLPDNGHLTRNAVLGFARQLDQPLAQWIEENV
                     SFPGTMVDRIVPAMTESQFALLETKTGYADPCGIVCESFRQWVIEDNFVRGRPEWDKA
                     GAMFVSNVQPYEEMKLRMLNGSHSFLAYNGSLAGYEFIWQCMEDANFRSITHQLMINE
                     QARTLNPDLNINIQEYADLLIERFSNRNVAHRTGQIAMDGSQKLPQRALTPWLKLHQQ
                     KQNNAVLSLLVAGWLHYVIDVVEKSQSVADPMNDQF"
BASE COUNT         6705 a         7093 c         6680 g         6363 t
ORIGIN      
        1 cttcataatc agtacggggt tgctacaaca tgtattactt tttcaccaca attaacggtt
       61 caatatcact ctcttttttg atgaccagtg attcatcacc gcgcaaacac gtcccaccgt
      121 agttgccgcc aacggtgaag gtacatacct gaatgtattt accgtccact ttcggcaaac
      181 accacagttg ctggtaaata tttttctgtt cggcaaattt accactggtc tgatcaagca
      241 cctcttcatg atggctgacc aggtcaatgt tgctaccaca gcgcccggca atcggtttaa
      301 cggcataacc ggttttcacc agctcatcat tcacggtgaa gtcagtatcc aacagataac
      361 gatggtgcgg gaacagagac cagaggatcg gcagaatcgc tttgttaccg gggatcaccg
      421 tccatagcgg ctcaaaaacc aacacttccg ggcgcagcaa tacgtcgata agacgcactt
      481 cattttgtgg atgcccggta cggatcggca ctgcggcaaa ttcacggtcg ctcacttcgc
      541 ggatttgatc aaatgccgtt tcccacgccc aggttttcca tacgcagtta accagtcgcc
      601 cttccccatc aatcagttgc ccggcagcat cccagcccag ttcatccaac ccacgcaaga
      661 tacgcgtttc aaagcccgcc tggtgcagcg cctgctccat aaactgcgcg tgatagtttt
      721 cctcgatatc tttgtcctgc atgatatgga caaacggacg tgcacgactg tgtttccacg
      781 cgccagccag ttcgttaatc agtccttccg caggattgaa gccgttgcct ttatagccct
      841 gctccgccca acgttcgagg atcaagcccg cttcggtatg acaggaggca gaatcggcgt
      901 tgtattcgta gactttcagg ccacgttcat ccatgcagaa atccatacga ccagtgatca
      961 tatgatgacg gcgacgctgc caggagagac gcaaacgtgg ccagaggatt ttcggaatgt
     1021 caaacagcgc cagcaggttg tcatctttca gcaccttgtc ggtggcgtga agatacatca
     1081 ggtgcagctc gttggtggct ttaatcagct cctgctcggc actctcggta atggtgtagt
     1141 aatgatacgg atcctgattg atcacctggc cgttggcctg tacataggcg ttttgcagcg
     1201 gatctttttc atccagccat ttaccgtcaa actggccttt gttttccaga cgcgccccgc
     1261 tgattttcag cagttcgcct gcaatttccg gctgtggcaa gctgtattcg gtatcttccg
     1321 tctggatcat ccagcccaga atagtggtgt catcgaaggt gtctttcagg gtatagccgc
     1381 cgttttcgac caccatctcc agctcgcgtg tccactgttg cccttgcggc aacggggtat
     1441 gaatcacgtt ctgttccgca atacggactt tgttgccatg caattgggta atgatggcga
     1501 catggccagt gtctttaaat tcaccgcctt tatcccagat aagaagcgcc cccgctaccg
     1561 gtgcacgcgg cgaaccgtta ggaaatgcct gcaatggcag gatgttgtca ttgaccactt
     1621 cacgcaggaa gcgcagtgag aaaatctccc atgccatacc cacgtcagtg aagactacac
     1681 cgtagttcag aaagagaaaa cggcgagcaa attcaacgca ttgccatttg tggcccatat
     1741 attcatcgtc gatatagcta cggaatacgg cgtcatcttc gtattcctgc ggatcgagag
     1801 aactgtaatc tgaagagtag attgctaccc cacctggggc gtagcccaat aatgtcccga
     1861 acggggcatc ctggctggtc gttcctttgc tcatcacttt acctttaaca atacaaccta
     1921 agcagttggc gtaattgttg tgctctgatt acctgctcag cgacattaac cggacagagg
     1981 tcagactaat catacacctc atcgcagcgg ctggcgcaaa gggttaaaaa attcacattc
     2041 tgtacagcaa gtgacctgct acactgcttc aacactacca ctcagaaggc aactcactat
     2101 gacagacaat acttatcagc ccgcgaaagt ctggacgtgg gataaatccg ctggcggcgc
     2161 gttcgccagt atcaatcgcc cggtttctgg tccgacgcat gaaaaaacgc tgccggtggg
     2221 caaacatcca ttgcaacttt attcgctggg aacgccgaac ggtcagaaag taacgattat
     2281 gcttgaggag ctgctggcac tgggcgttac tggtgcagag tacgacgcct ggctgattcg
     2341 tattggcgat ggcgatcaat tctccagcgg ctttgtcgaa gtgaacccaa actcgaagat
     2401 cccggcgctg cgcgaccata cccataatcc accgatccgc gtgtttgagt ctggatcgat
     2461 tctgctttat ctggcggaga aatttggcta cttcctgccg caggatttgg caaagcgtac
     2521 tgaaacgatg aactggctgt tctggttaca gggcgcggca ccgttcctcg gcggtggttt
     2581 tggtcacttt taccattacg cgccggtgaa aattgagtac gccatcaacc gctttaccat
     2641 ggaagccaag cgcctgctcg acgtgctgga taagcaactg gcgcagcaca agtttgttgc
     2701 gggcgatgag tacaccattg cggatatggc gatctggccg tggtttggca acgtggtgtt
     2761 aggcggcgtg tatgatgccg cagagtttct ggatgcgggc agttataagc acgtgcaacg
     2821 ctgggcgaaa gaagtgggcg aacgtccggc ggtgaagcgt gggcgtattg ttaaccgcac
     2881 caacgggccg ctgaacgagc agttgcatga gcgccatgac gccagtgatt tcgagacgaa
     2941 tacggaagat aagcgtcagg ggtaagtcgc aacattggca ggcttatcgc tatgtagccg
     3001 gataaagcat ttacgccgca tccggcttta atcatcacgc gctggtaatg tcgtaatcca
     3061 tttggcgcag tgcgtctaat gtggctttgg cttcatcttc gtcgatgatg ctcatggcaa
     3121 atccgacgtg taccagcacc cactggccca gcagatcggc agggttacct tcacaaatca
     3181 gggcgatatt cacgtcgcgc ttgataccac atacttcaac ctgcgcaagc tggtgaatat
     3241 cttcaccgac agccagcacc tggcctggaa cgccaataca cattgttaac tccagttatt
     3301 caacttcaat acttttgacg atcagcgaat cgccggtatc gacacgcaac cgctcgccat
     3361 gacagagcgg acactgcgca tcgtgctgat gaatctccac cacctggctg caatcccagc
     3421 accaggcctg ggcgggttta tagacgatat gtaaatcgca cccttgcgcc accgttccgt
     3481 ggcagacaat ttcaaaacta aaacggacgg cgctctcctc aacgcaggag agcgcgccaa
     3541 tttccagcca cacggcggtg acgcgcttaa catcgtgctg ctccgcctgc cgttggataa
     3601 tttcaacggc gctctggcaa agcgacaact catgcatttt cgccactcct gcgaccaaac
     3661 agcagggcgc gacgccctgc gtgtggtaca tccggattag cgaccggtag cgaaaggatc
     3721 atccgcgcgc agtcatccgt caggcgttgg ccctcttcaa tcgacatgct atgcgaaagc
     3781 ggtgacatca gcgaacagga gagatattga gaaacactgt ccagttcgcc aacggtaaag
     3841 gtcatagtgc catacggcag ttgcagacca attttttcac tcactttgcg cagcggccag
     3901 agttgatccg ggccggggaa gataactgca ctcagcatcc acggggtgat cacacacccc
     3961 gtccactgac cttcgaacag cgtaaagtca gaaacataca ccggcattga gggatgcaga
     4021 aaagagagat cgtgcatcga acgccgggca atttcttcaa acgctgcctg tacttgcgcc
     4081 ttcggggagg tctggaaacc tgctatctct tcagtcatga gtcgcctccc gtgggatagc
     4141 ttccacgcct gattcgcgca gcgcagccag aacctgctca agcgcaggtt caatcattgc
     4201 ttcaaccgtc ggcgttaagc cgatgtgcgg ctccagcgat tccgggatca caccgaccag
     4261 cgtcagcttt ttcggaaact cgccggtgaa gcgcagggcc gacaatacgt cggccaggcc
     4321 aagctgatgc ggagagattt tgttggtaaa caacgccgga acttcttcat cccgcaggat
     4381 catcatcgtt cccggcgcgt tctttttcga cacaatggca tccgcaataa tcagatgatc
     4441 gcgatttgcc atgtcgccaa gcagctccat tcccgccgtg ccgccatcga ggatctcaac
     4501 ataatccggc agaatgtatc gttgctctaa cgcttcaaca atccgcacac cgatggcttc
     4561 atcggtcagc aaaatattgc cgacccctaa gactaaaata cgcattacag aaccttcact
     4621 gaaaccactt cgttgccgtc ggcatccact acgtgtaccg cacaggccat gcacgggtcg
     4681 aaggagtgaa tggtacgcac cacttccagc ggtttattcg gatcggcaac cggtgtaccc
     4741 accagcgact gctcgtaagg accgacgtca tcattgaagt tacgcggacc agagttccag
     4801 gttgatggaa caaccgcctg gtagttgctg atgataccgt ctttaataac catccagtga
     4861 gagagcatac cgcgcggcgc ttcgaggaag ccaacacctt tgaactcacc cgttgccgga
     4921 atgttcggct tcacaaaggt ggtgtgatcg cctttgccga tattggtgat cagtgcactg
     4981 tattggtttt gcaggatatc ctgcaattca cagcagtgaa cggtacgacc aataatacgg
     5041 cccagcgtgg agtgcagctg tgccacttcc agcgtgttgc cagtcagttt ctgataaatc
     5101 gcaacgattt cattcagttt gttctgggta gattcgcgac ctgccgccag tttcaccagc
     5161 atattagcca gcggacccac ttctaccgtt ttgccgtaga aagtcggcga tttcacccag
     5221 gaatatttac cgtcatcaga ccaaccgtcg taagccggaa tggtggtacc ttcccacggt
     5281 gcctgcggcg cttcgtcttt ataccaggag tgcttcgcgc tttcctgaat gcctttgatc
     5341 aggtattcat cggaatgaga agtgatcgga cgatacgagg acagatccgc attctcaatg
     5401 tagccgcccg ggaacaggaa gctgccgttt ttgctgtcgg tcgggaattc cggcacgctc
     5461 aggtagttca ccgcaccttt accgcgcgtc agccattccg ggtagaacgc ggcgataact
     5521 gcggtatcaa ccttataaac ctgttcaaca aagtcgctca gcttgtcgat gaaagacttg
     5581 atgtacatca ggcgctcaag gttcagcacg cccaaaccgt cgaggttgat tgggttagcg
     5641 accccgccta ccgccaggtt ctgaatgtgc ggcgttttac cgcccagcag cgccacgacg
     5701 cggttagcgt cacgctggca ctccagcgcc tgcaggtagt gcgctaccgc aatcaggttc
     5761 acttccggcg gcagtttcat cgccgggtga ccccagtagc cattggcgaa aatacccaac
     5821 tgaccgctgg caaccagatc tttaatcttg ttctgaactt tggtgaactc ttccggactg
     5881 ttcagatgcc aggtcgaaac gcctttcagc atttcagagg ctttggttgg gtcagcttgc
     5941 agtgcagaag tgatgtccac ccagtccagc gccgaaagct gatagaaatg aacgatatgg
     6001 tcatgcgtgg tgtgcgcagc cagaatgatg ttacggatgt attgcgcgtt aaccggaacg
     6061 tcgatattca gcgcactttc tgccgcacga acggaagaca gcgcgtgagt ggtagtacat
     6121 acgccacaga tacgttgcac aatcatccat gcatcgcgcg gatcgcggtt tttcacgatc
     6181 tcttccatgc cgcgccacat ggtaccggaa gcccatgctt tcgaaacgac gccattttcg
     6241 atttcgcaat cgatgcgtaa atgcccctca atacgggtta ccggatcaat agtaattctc
     6301 tggctcatgc tttgctcgcc tcatgacgat tatgatcgtt ttgttttaaa ggaggaagta
     6361 tcggcagtag acgaatgagt acgatgtaag cgcaaatctc aatagccaca aaaccaatag
     6421 aaatcaacag ttcttcccag gtcgggaagt aggcgtaacc gccgcccggg ttgaatgcca
     6481 ccagcgaata ggtcagacgc caggttgcac aacctaacag tgcgctcagt gctgacagga
     6541 acagcatgcg ggaatcatta cgcagcttcg ccacacgcag aacgaccagc gggaagagca
     6601 tcagcaggac ttcaatccag aacatcacgg agtagaagtc accggcaaac gctaacgaca
     6661 gcttgtcgcg atagataagc tcgccaaagc gcagcacgat gaaaatcgcc agcaacacac
     6721 tgatggtgtt ggtcagcttg acgaacaggc tcttttcatc cggaccgttg ccacgcagac
     6781 ccgcctgcac cagtgaacct tcaaagatga caatcgagaa gcccatgatg aacgccgtca
     6841 gcagcgagaa cagcggcaac atttcatagc tctgccacag cggatgcacc ttgtagcccg
     6901 ccgagatcat cagcgacccc attgaagact ggtgcatggt cggcagcagc gcaccgagcg
     6961 cgatgatgaa gaacatcacc ttgttcagac gctgtagcga caccttccag cccagacgtt
     7021 caaacagtgc cggagcaaac tccagtgcca tcacgccgat atagatggtc atacagaccg
     7081 ccgtctcgaa cagtaccgag ttcacgttga agtgacccgg aatgtagaag tacggcaggt
     7141 tccagtagcg acccacgtcg atagtgatcg acaagccacc tagtgagtaa ccaaacagac
     7201 tcgccaacag cgccggacgc accagcggat ggtattgccc acggttaaag acgtataccg
     7261 cccacgccag cgcccagccg ccacaggcaa agccggtgcc gatcaacagg tcaaacgcga
     7321 tccacacgcc ccacgggaag ccgccgttca ggtcagagac agagcccaga ccgaacacca
     7381 gacgcttcac aatcaggagc atacagatga cgattaacgg tccaaaaatc atgaccggtt
     7441 tactgatgat tttgccgccc agcggttgtg gatcatgact catgatcgtc tcctccgtcg
     7501 tgatggtcgt ttttggtgtt gcgacgaacc agcacggtta agcccgccag cacagccagt
     7561 ggtagcatca tgcctttata cagggtgtgt tgaatatttt cggaacgcgc accggtagaa
     7621 agatcgtcca gtttcggcag gtcgagattt tcataaggca cacccgtcag taccagaacc
     7681 tgagtaccgc cgccctcttt ctcgccgtac agatgcggat aatatttcgg caccgtatgc
     7741 aggtaagtgt cgccagattt cagcgtctga cgcggatagt ggtattcgct gccaggcttc
     7801 agcgccagac gttttttcgc ctccgccatc agctcttcac gcgtaccaaa aatcaccgcg
     7861 cccgccgggc acacttctac gcagccaggc agaccgcctt tatcgagacg ttccacacct
     7921 ttctggttgc acaactcgca cttatgcagc gcaccaaacg ggttgttgta gtcgtacttc
     7981 ggcacgttgt atgggcaggc gaccatgcag taacggcagc cggtgcacac atctttgtcg
     8041 taatggacaa tgccggtttt cggatctttt ttcagcgcag agaccgggca cacagagaca
     8101 cagttcggat cgacgcagtg catacactgt ttcttaatgt acgcgtagcc attctcctcc
     8161 tggtctttgt tgacccctgt gccgctggtc cacacctgaa tgatgttatt ggtatacggc
     8221 gacagtttgt cgttgttcga ccaggtctgt tccccttgcg ggttacgttc aggggagttg
     8281 atatcctgac acttggtgac gcaagcctga cagcctacgc acaaggtcga gtcgtacaac
     8341 atccccagcg atcccggaat tggcgggcgg ttttcagcag ccgcatgact gacagacggc
     8401 agcgcgcccg tcagcaatgc cccgcaggag gctgctttaa taaaattacg tctgttcacg
     8461 gttattctcc ccgtgagtca gcgttatctt tcttttgctg acgacccagt tcacgcaccg
     8521 ccatcacgct gacaccggca accagcccaa ccactccgcc gagcaaacca atagcgcctg
     8581 ccgagacgtt gccgccttct ttagcgttaa cgtccggttt ctgtgaacgc ggagtctggt
     8641 tttcgacgtt ggcaagctga tggatgcctt tatggaagcc gataccttct tcgttacagc
     8701 catagcacgg gtgaccaatc gctaccggcc acacgccgcc aacatcgcag aattgcagcg
     8761 ttgagcagtt gccgtaagtt tctggccctt tacagccgag gtggtacagg caccagcctt
     8821 cgcggtggcc ttcatcaccg aactctttgg caaaacgacc agcatcgaag tgcgggcgac
     8881 gttcacagtg ttcgtgaatc agacgaccat aggcgaaagt cggacggttt ttgtcatcca
     8941 gtttcggcgg tttgccgtaa gtgatgatgt gcgcaacggt cgccaggaag ttgtgcgggt
     9001 tcggcgggca gccaggaata ttgataacgg ttttgcccgg tagaacttct tgcaggctga
     9061 ctgcgccagt tgggttaact ccagctgcgg caacaccgcc ccacgcagag caggaaccga
     9121 tagcgataat ggctgctgcg ccttccgccg ctttgcggat gtgatccaca atcggctcac
     9181 cggcaaccat gcaataaata ccgttatctt ttaatgggat ggaaccatcc accactaaca
     9241 catactgccc tttgtacttc tcgagagcgt tatgtttgtt ctcttcgacc tgatgaccga
     9301 aggcggcgga aagcacttcg tgatactcca gagagatagt ctccagcacg aggttttcta
     9361 ccgttggatg cgttgcacga agcagagatt ccgtacaacc ggtgcactcc tgcgcgccaa
     9421 tccagataac tggcggacgc tgcgggttag taaccgattc gaccatctct gcagcggctt
     9481 tgctacttaa ccccatggtg gcggctaatg ctgcacaaag cttcatgaaa tcacgacggt
     9541 taatgccgtg agaatggatg agggtgttat ctccagtcat ttatagttat tccgttgcga
     9601 agacctggca tatattttgc ctcaatcgca aaatcaataa tgcgatcgat gcgccattta
     9661 ccacacattt attatggtta tcgatatcat gatactgcgg cggggcacta aaacgaaggg
     9721 aagaagcatt agtgtaatta attaaagcaa gataatacgt atgtttgatc aattttctag
     9781 gcgataaccg gccataaaaa agcgcaacgt agaacaggaa ttattctcac gaaagaaatc
     9841 cattaccatc tctttatcca gtccataacg gcgcgtcaga atacccgctt cccaggcgct
     9901 aagctggcga tctccggtct tttcgtacat ccggtgtgag tagcctaata caaaaccgcg
     9961 tttataatcg gcacagaatt ttgtcacatt aaccgcactg tcggcatgcg ttgcttttaa
    10021 tcccgccatt aagcctttac caaaatggtt attcatcgtt cacctcattc gctatatatt
    10081 gtcatatata gcgatatttt aggcaaagaa cgacatttgc gcacgctatt ttttcatgct
    10141 tgtttaagac gtaatcctgt aagagataaa cccatcagga gagatattta tcgaaccatt
    10201 tcagcgtcct ttgccaggca agatcggcgg cagatttgtc ataacggggc gtggaatcat
    10261 tatggaatcc gtgattaacc cccggatata tatacgcctc atagacctta ttattggctt
    10321 tcaacgccgc ctcgtaagcg ggccagccct cgttgattcg gctatccagt tcagcgtagt
    10381 ggagcagtaa aggcgcttca atcttcgcca catcggcagt gggtgcctga cgcccataaa
    10441 acggcaccgc gcaggccagt tccggatacg cgactgctgc cgcgttcgat acgcccccgc
    10501 catagcaaaa tccgctaata cccactttgc ctgtcgcttg cggatagcgt tgcataaact
    10561 caattgcggc aaagaaatca ttcatcagtt tggttggatc aacctgctgt tgcagttcgc
    10621 ggcctttatc atcgttacca ggatagccac ctactgagct taaaccgtct ggcgccaggg
    10681 cgatgtaccc agccttcgcc actcgccgcg tcacatcttc gatatacgga ttcagccctc
    10741 gattctcatg caccactacc acggctggcg ttttgccgct catttttgcg ggcttcacca
    10801 gataaccccg tacctcgccg tgaccatttg gcgagggata cgtgatgtac tcagcaacaa
    10861 tttccgggtc ggtaaactct acctgagtcg ccaacgcata atttgacttg agcaaatcaa
    10921 acagcgctaa tgccgtcatc ccgcccaccg catacttcgc cgcaaggttg aggaactcac
    10981 gtttcgagat tttcccgtga gcgtaatagt cgtagtaatc cagcaactct tgtgggaaat
    11041 ctttggcggt taaacgcggc atcgttgcac tcctcaactg gtgttttttt aagcaaagca
    11101 taagcgcgtg tttttgccca gtttttcgtc actctgtgag ccagactacg ggatacgcgc
    11161 tggcgaatcg ctaaactaga aacattgttt cgaaattgaa cgatggaaag gagaggtcat
    11221 ggtctggtta gcgaatcccg aacgttacgg gcagatgcag taccgctatt gcggaaaaag
    11281 tggtttacgc ctgcccgcgt tatcgctcgg tttatggcac aatttcggtc acgttaacgc
    11341 gctggaatca cagcgtgcga tcctgcgtaa agcgtttgat ttaggcatta cgcactttga
    11401 tttagccaac aactacgggc cgcctccagg aagcgcagaa gagaactttg gtcgcctgct
    11461 gcgcgaggat tttgccgctt atcgcgatga actgattatc tctaccaaag ccggatacga
    11521 tatgtggccc ggcccatacg gctctggcgg ctcacgtaaa tacctgctcg ccagcctcga
    11581 ccaaagcctg aagcgtatgg ggcttgagta tgtcgatatc ttttactctc atcgcgtcga
    11641 tgaaaatacg ccgatggaag aaaccgcctc tgcgctggct catgctgtac aaagcggtaa
    11701 ggcgctgtat gtcgggatct cctcttactc gccagagcgg acgcaaaaaa tggtcgagtt
    11761 gctgcgcgag tggaaaattc cgctgttaat tcatcaacct tcgtacaatt tactgaaccg
    11821 ctgggtggat aaaagcggcc tgctggatac cctgcaaaat aacggcgtgg gctgcattgc
    11881 ctttactcca ctggcacagg gattgctgac cggaaaatat ctcaacggta ttccgcaaga
    11941 ttcacggatg catcgtgaag ggaataaagt tcgtggtctg acgccgaaaa tgctcaccga
    12001 agccaacctc aacagcctgc ggttattgaa tgaaatggca cagcagcgtg gacaatcaat
    12061 ggcgcaaatg gcgttaagct ggttgctgaa agatgatcgc gtgacgtcgg tattgattgg
    12121 tgccagccgc gcggagcaac ttgaggagaa cgtgcaggcg ctgaataatc tgacatttag
    12181 caccgaggag ctggcgcaga ttgatcagca tatcgccgat ggcgagctga atctgtggca
    12241 ggcgtcttcc gataaatgac ctgttaataa cgggcgcgag aaccgcgccc gaatcagatc
    12301 agtgattatg acgagtcagt cggtcaagat agcccatcac aaatgcagag agcacaaacg
    12361 tcagatggat aatgacgtac cacatcagtt tgttatccgg gacatttttc gcatccataa
    12421 agacgcgcag taagtgaatg gaagaaattg ccacaatcga cgctgctact ttgtttttca
    12481 gcgacgttgc atccattttc cccagccagt tcagcttctc tttgttctcg gagatatcca
    12541 gttgtgagac gaaattctcg taaccggaaa acatcaccat caccagcaaa ccgccaacca
    12601 gcgtcatatc caccagcgac agcaacacga ggatcaaatc tgattccgcc atcgagaaga
    12661 tattcggcag tacgtgaata atctcctgga agaacttcag cgccagggca actaacgcca
    12721 gcgaaaggcc aaagtacacg ggggcaagca gccagcgaga agcatacatt gcattttcaa
    12781 gaaaacgttc catacattcc tgtcgtgtag ttaaaacgag caacagtata tcgcaattaa
    12841 gtaaacagca cgcaacagca aatcaacata tacgttaaac ctttgtcgca taattctgag
    12901 ggttagggat cttcctggtt cccttatcaa cgcatcgaga gcgtctaccc ttaaaggacg
    12961 ttgaacctga agggagaaaa atgatgtctc atttaaaaga cccgaccacg cagtattaca
    13021 ctggtgaata tcccaaacag aaacaaccga cgccaggcat ccaggcgaag atgacaccgg
    13081 taccggattg cggcgagaaa acctatgttg gtagcggtcg cctgaaagat cgtaaagcac
    13141 tggtgacagg gggcgattcc ggaatcggtc gcgctgccgc cattgcttac gcgcgtgaag
    13201 gggctgacgt ggcgatcagt tatcttcccg tggaagaaga agacgctcag gatgtgaaaa
    13261 agatcattga agaatgcgga cgcaaagccg ttctgctgcc aggcgattta agcgatgaga
    13321 aattcgcccg ttcgctggtt cacgaagcac acaaggcgtt aggcgggctg gatattatgg
    13381 cgctggtagc cgtgaaacag gttgccattc ctgatattgc agacctcacc agcgaacagt
    13441 ttcaaaagac ctttgccatt aacgttttcg cgttgttctg gctaacccag gaagcgatcc
    13501 ccctgctacc gaaaggtgca agtatcatca ccacttcctc aatccaggca taccagccaa
    13561 gcccgcattt actggactat gcggctacga aggcggcaat tctgaactat agccgtggcc
    13621 tggcaaaaca ggtcgcggag aaaggtattc gggtgaatat tgtcgcgcca ggcccgatct
    13681 ggacagcact gcaaatttct ggcggacaaa cgcaggataa gatcccgcag tttggtcaga
    13741 aaacgccgat gaagcgtgcg gggcaaccgg cggagctggc ccctgtatat gtttacctgg
    13801 caagtcagga gtcgagctac gtcaccgcag aagtgcacgg tgtctgcggc ggcgagcatt
    13861 taggttaaaa aaatgcccgg ttgtgaaaag caaccgggca tcatttttat ttcgctttcg
    13921 cagtttcttc gccgaccaga cctattttca ggtaacccgc ctgatgcagc gtatccatta
    13981 ccttcatcaa cgtctcgtaa tcgacggttt tatccgctcg gaagaagatg gtggtgtctt
    14041 tcttgccttc ggttaacgca ttcaacgccg taatcattgt ttcatcggtg accggatcgt
    14101 taccaataaa catcgagttg tctgctttca ccgacagata aaccggtttt tccgggcgcg
    14161 gctgcggcgt actggtagaa gcaggcaaat tcaccttcac atctaccgtc gctaacggtg
    14221 ccgccaccat aaagataatc agcaaaacca acatcacgtc gataaacggc gtcacgttga
    14281 tatcatgcat ttcgccgtta tcgtcgaggt tttcgttaag atgcatcgcc atcggacatt
    14341 atcctgcgcg taatttttgt gcgacacgaa ccggatgtgc agcggcgctg gcttccagat
    14401 ccaggtcacg gctttgcagc aacaatacct gcgctgcaac atcacccagc atcgctttaa
    14461 agccgccaat ctggcgtgca aatacgttat agataacgac cgcaggaatc gctgccacga
    14521 ggccgattgc cgttgctaac agagcttctg caatacccgg cgcaacgact gccaggttag
    14581 tggtctgcgt ttgcgcgata ccaataaagc tgttcatgat gccccagacc gtaccaaaca
    14641 gaccaacgaa cggcgaaatc gcgccgatgg ttgccagata gccgttacca cggcccattt
    14701 gacgacctac tgcggcgacc cgacgctcca gacggaagct ggtacgttct ttaatacctt
    14761 cgttatcgtc gctgccttct gacagttcca gctcattctg cgcttcattg agcaaatgca
    14821 ggctcaagct tttgctacca aaatcagcgg cgatatcgtt ggcctggttt aaggaacgcg
    14881 cttcagccag caattgctgc tcgcgcttaa gacgacgctt ctgattgaag aactccacgc
    14941 tcttactgaa gaagattgcc caggtgacta cggaggccaa aataagccca atcatcacgc
    15001 acttaacgac aatatcggcg tgctgataca taccccagac ggagaggtcc gtctgcatta
    15061 aattattacc cactgtgtat ctccaggacg caagtcacaa aatctgtgca taataatatc
    15121 aaaacgacgt cgaattgata gtcgttctca ttactatttg catactgccg tacctttgct
    15181 ttcttttcct tgcgtttacg cagtaaaaaa gtcaccagca cgccatttgc gaaaattttc
    15241 tgctttatgc caattcttca ggatgcgccc gcgaatattc atgctagttt agacatccag
    15301 acgtataaaa acaggaatcc cgacatggcg gacaaaaagc ttgatactca actggtgaat
    15361 gcaggacgca gcaaaaaata cacgctcggt gcggtaaata gcgtgattca gcgcgcgtct
    15421 tcgctggtct ttgacagtgt ggaagccaaa aaacacgcga cacgtaatcg cgccaatggc
    15481 gagttgttct atggacggcg tggaacgtta acccatttct ccttacaaca agcgatgtgt
    15541 gaactggaag gtggcgcagg ctgtgtgcta tttccctgcg gggcggcagc ggttgctaat
    15601 tccattcttg cttttgtcga acagggcgat catgtgttga tgaccaacac cgcctatgaa
    15661 ccgagtcagg atttctgtag caaaatcctc agcaaactgg gcgtaacgac atcgtggttt
    15721 gatccgctga ttggtgccga tatcgttaag catctgcagc caaacactaa aatcgtgttt
    15781 ctggaatcgc caggttccat caccatggaa gtccacgatg ttccggcgat tgttgccgcc
    15841 gtacgcagtg tggtcccgga tgccatcatt atgatcgaca acacctgggc agccggtgtg
    15901 ctgtttaagg cgctggattt tggcatcgat gtttctattc aggccgccac caaatatctg
    15961 gttgggcatt cagatgcgat gattggcact gcggtgtgca atgcccgttg ctgggagcag
    16021 ctgcgagaga atgcctatct gatgggccag atggtcgatg ccgataccgc ctatataacc
    16081 agccgtggcc tgcgcacatt aggtgtgcgt ttgcgccaac atcatgaaag cagtctgaaa
    16141 gtggctgaat ggctggcaga acatccccaa gtagcgcgag ttaaccaccc tgctctgcct
    16201 ggcagtaaag gccacgaatt ctggaaacga gactttacag gcagcagcgg gctattttcc
    16261 tttgtgctta agaaaaaact caatgatgaa gagctggcga actatctgga taacttcagt
    16321 ttattcagca tggcctactc gtggggcggg tatgaatcgt tgatcctggc aaatcaacca
    16381 gaacatatcg ccgccattcg cccacaaggc aagatcgatt ttagcgggac cttgattcgc
    16441 ctgcatattg gtctggaaga tgtcgacgat ctgattgccg atctggacgc cggttttgcg
    16501 cgaattgtat aacattgcca cttttggaca attttgcaga cattttattg tgaaaagtct
    16561 taaattgttg cgtccgggat caaggcgtcc cggacgattc aggagtacaa taggcagata
    16621 aaggcttaaa cgctgttcca caggaaagtc catggctgtt attcaagata tcatcgctgc
    16681 gctctggcaa cacgactttg ccgcgctggc ggaccctcat attgttagcg ttgtttactt
    16741 tgttatgttt gccacgctgt ttttagaaaa cggcttgctg cccgcctcat ttttgccagg
    16801 cgacagcttg ttgatactgg caggcgcatt gattgcccag ggggttatgg attttctgcc
    16861 tacgattgcg attctgaccg ccgcagcaag tctgggctgc tggctaagtt atattcaggg
    16921 gcgctggtta gggaatacca aaacggtgaa aggctggctg gcacagcttc ctgctaaata
    16981 tcaccagcgc gccacctgca tgtttgaccg ccacggtctg ctggcgctgc tggctggacg
    17041 ttttcttgca tttgtccgta cgctgctgcc aaccatggcg ggaatttccg gtctgccaaa
    17101 ccgccgcttc cagtttttca actggttaag cggattgctg tgggtcagcg tggtaaccag
    17161 tttcggctat gccttaagta tgattccgtt cgttaaacga catgaagatc aggtaatgac
    17221 gttcctgatg atcctgccaa ttgccttgtt aaccgctggc ttgttgggca cgctgtttgt
    17281 ggtgattaaa aaaaaatact gtaacgcctg acgattttcc ccgttcccgg ttgctgtacc
    17341 gggaacgtat ttaattcccc tgcatcgccc gcattcttgc cgcatcttcc cccggcgtca
    17401 caccgaagta acgtttaaac tcacggctaa attgcgatgc gctttcatag ccgacgcgca
    17461 tcgccgccgc gctggccttc atgccgtcgt ggatgatcat catccgcgcc ttatgcagac
    17521 ggtaattctt caaatactgc aacggcgagg tgctggtgac agacttaaaa ttatggtgga
    17581 acgccgatac gctcatgttg gcttctgccg ccagttgctc gacgctcagg ttttcggtgt
    17641 atttattctc aatccgtttc agcacgcgac taatcaggct gaagtgagtc tggcggctga
    17701 ccagtgccag taacgcgccg ccgcaaggtc cggtcagcac gtagtacaga atttcgcgga
    17761 taatctgttt gccgagaatg cgcgcatcca gcggtcgctc catcacatcc agtaaccgct
    17821 ctgccgcgca taaaatctct tctgataacg tggcggagtt aataccgctg gctgccattg
    17881 acggctgaaa atgttcatct tcgccaatgt ccatcaacag ttcctgtaac tgcaaaatat
    17941 cgacattgag acgcaaccct gccagcggca cctctgacgt ggcataggtt tcgcactcaa
    18001 acggcaacgg caccgtcagc aggagatatt cattagcgtc ataacgaaac acgcgttcat
    18061 tgatataacc gattttatgt ccggaaaaga gaattatgat gccaggctcg tacatcaccg
    18121 gtgtgcgtgc gaaaggcgtc tcgccataca acaaacgcac atcgggcaac agctctgaca
    18181 aactattttc tttatttttc agtttattaa ctttatccgc cagcaagcgg caaatctctt
    18241 cacgtttcat atcgcgtaat ttcttaggaa taatgcggca atttgattgt gcgcaatttt
    18301 gtagcatttc tccagcactc tggagaaata ggcaagacat tggcagaaat gagcattgag
    18361 aggtacggcg ctggcgacca caatgaaaaa catcaggcag accgatctct gccctcatat
    18421 tgacccagca aagggagcaa gtaatgaaca actttaatct gcacacccca acccgcattc
    18481 tgtttggtaa aggcgcaatc gctggtttac gcgaacaaat tcctcacgat gctcgcgtat
    18541 tgattaccta cggcggcggc agcgtgaaaa aaaccggcgt tctcgatcaa gttctggatg
    18601 ccctgaaagg catggacgtg ctggaatttg gcggtattga accaaacccg gcttatgaaa
    18661 cgctgatgaa cgccgtgaaa ctggttcgcg aacaaaaagt gacttttctg ctggcggttg
    18721 gcggcggttc tgtactggac ggcaccaaat ttatcgccgc agcggctaac tatccggaaa
    18781 atatcgatcc gtggcacatt ctgcaaacgg gcggcaaaga gattaaaagc gccatcccga
    18841 tgggctgtgt gctgacgctg ccagcaaccg gttcagaatc caacgcaggt gcggtgatct
    18901 cccgtaaaac cacaggcgac aagcaggcgt tccattctgc ccatgttcag cccgtatttg
    18961 ccgtgctcga tccggtttat acctacaccc tgccgtcgcg tcaggtggct aacggcgtag
    19021 tggacgcctt tgtacacacc gtggaacagt atgttaccaa accggttgat gccaaaattc
    19081 aggaccgttt cgcagaaggc attttgctga cgctgatcga agatggtccg aaagccctga
    19141 aagagccaga aaactacgat gtgcgcgcca acgtcatgtg ggcggcgact caggcgctga
    19201 acggtttgat cggcgctggc gtaccgcagg actgggcaac gcatatgctg ggccacgaac
    19261 tgactgcgat gcacggtctg gatcacgcgc aaacactggc tatcgtcctg cctgcactgt
    19321 ggaatgaaaa acgcgatacc aagcgcgcta agctgctgca atatgctgaa cgcgtctgga
    19381 acatcactga aggttcagac gatgagcgta ttgacgccgc gattgccgca acccgcaatt
    19441 tctttgagca attaggcgtg ccgacccacc tctccgacta cggtctggac ggcagctcca
    19501 tcccggcttt gctgaaaaaa ctggaagagc acggcatgac ccaactgggc gaaaatcatg
    19561 acattacgct ggatgtcagc cgccgtatat acgaagccgc ccgctaagct ttttacgcct
    19621 caaactttcg ttttcgggca tttcgtccag acttaagttc acaacacctc accggagcct
    19681 gctccggtga gttcatataa aggaggaacg tatggctaat ccaaccgtta ttaagctaca
    19741 ggatggcaat gtcatgcccc agctgggact gggcgtctgg caagcaagta atgaggaagt
    19801 aatcaccgcc attcaaaaag cgttagaagt gggttatcgc tcgattgata ccgccgcagc
    19861 ctacaagaac gaagaaggtg tcggcaaagc cctgaaaaat gcctcagtca acagagaaga
    19921 actgttcatc accactaagc tgtggaacga cgaccacaag cgcccccgcg aagccctgct
    19981 cgacagcctg aaaaaactcc agcttgatta tatcgacctc tatttaatgc actggcccgt
    20041 tcccgctatc gaccattatg tcgaagcatg gaaaggcatg atcgaattgc aaaaagaggg
    20101 attaatcaaa agcatcggcg tgtgcaactt ccagatccat cacctgcaac gcctgattga
    20161 tgaaactggc gtgacgcctg tgataaacca gatcgaactt cacccgctga tgcaacaacg
    20221 ccagctacat gcctggaacg cgacacacaa aatccagacc gaatcctgga gcccattagc
    20281 gcaaggaggg aaaggcgttt tcgatcagaa agtcattcgc gatctggcag ataaatacgg
    20341 caaaacccct gcgcagattg ttatccgctg gcatctggat agcggcctgg tggtgatccc
    20401 aaaatcggtc acaccttcac gcattgtcga aaactttgat gtctgggatt tccgtctcga
    20461 caaagacgaa cttggcgaaa ttgcaaaact cgatcagggc aagcgtctcg gtcccgatcc
    20521 tgaccagttc ggcggctaac gtgcaaatta tcccggtggc ggtaatgttc cgctaccgga
    20581 cttttcagaa atcatttatt cccctcgcgt cccgcccgtt gctactcttc cttgttcagg
    20641 aatgccaaat ataaggacat catcatgcag agccggaagc tcttaaaaga acaacccatc
    20701 tatatccggg ataaacgcaa cggagaggtg aaaaacagat gaaaataata cttctgtttt
    20761 tagcagccct ggcaagtttt accgtacacg cacagccccc ctcacagacc gtagaacaaa
    20821 cagtccggca tatttatcag aactataaat cagatgccac tgccccttat tttggtgaaa
    20881 ccggagagcg agcgataact tctgcgcgta ttcaacaggc gcttatcctg aacgacaatc
    20941 ttacgctgcc gggcaatatt ggctggctgg attatgatcc ggtttgtgat tgtcaggatt
    21001 ttggcaatct ggtgttagaa agcgtagcga taacccaaac tgacgccgat catgccgatg
    21061 ccgctgtgcg ctttcgtatc tttcaagacg ataaagaaaa gacctcgcag acactgaaaa
    21121 tggtggcgga aaatggtcgt tgggtcattg acgatattgt cagcaatcat ggcagcgtct
    21181 tacaagcggt taatagcgag aatgaaaaaa cgctggccac tatagcttcg ttgcaaaaag
    21241 aacagccgga agcctttgtt gccgaactct ttgaacatat tgctgattat agctggccgt
    21301 ggacgtgggt ggtttccgac tcttaccgcc aggcggtcaa tgccttctat aaaaccacct
    21361 tcaagacggc caacaatccc gatgaagata tgcaaataga acggcaattt atttacgaca
    21421 atccgatctg ttttggcgaa gagtcgttat tttcccgcgt tgatgaaatt cgagtcctgg
    21481 agaaaaccac cgattccgcc cgcattcatg ttcgctttac gctgaccaat ggcaacaacg
    21541 aagagcaaga actgatttta cagcggcgcg aaggtaagtg ggaaatcgct gattttatcc
    21601 gcccgaacag cggcagccta cttaagcaga ttgaggcaaa aaccgccgcc agattaaaac
    21661 aatgagctga attaaataac aattagccgg aacaataaat aaaagggaac actatatgaa
    21721 aacgattttc accgtgggag ctgttgttct ggcaacctgc ttgctcagtg gctgcgtcaa
    21781 tgagcaaaag gtcaatcaac tggcgagcaa tgtgcaaaca ttaaatgcaa aaatcgcccg
    21841 gcttgagcag gatatgaaag cattacgccc acaaatctat gctgccaaat ccgaagctaa
    21901 cagagccaat acgcgtcttg atgcacagga ctatttcgac tgcctgcgct gcttgcgtat
    21961 gtacgcagaa tgataaaaaa atccccggca gcattctgtt accggggata ttttttaacg
    22021 tccaaccgcc gctttagggc gtttcttcgc accagcattc tgcaggcgag attgcgtaga
    22081 cgacgctttt tttgccgtag caggcgtctg acgctgggtc gccatcggcg tatgtttagt
    22141 caacgccgga cgggtattgc ggttctggcg acgagcctca cgcatctctt caatagttgg
    22201 cgcaggcact aagcaatcgc gacggctgcc aatcagatgc tttttgccca tcgcttccag
    22261 cgcctggcgg attaacggcc agtttgccgg atcgtggtaa cgcaacaacg ctttatgcaa
    22321 acgacgctgt ttgtcgccct tcggcacgaa gacgtcttca ctcttataac caatcttcgc
    22381 cagcgggttt ttgccggtgt aatacatggt ggtcgagtta gccagcggcg acggatagaa
    22441 gttctgcacc tggtcgaggc ggaagcgatg ctttttcagc catagcgcca gattcaccat
    22501 atcttcatca cgcgtacccg ggtgcgcgga gatgaaatac gggatcagat actgttcttt
    22561 acctgcctgt ttcgagtaag tatcgaacag ctctttaaag cggtcatagc tgcccatgcc
    22621 cggcttcatc atcttcgata acggcccttc ttcggtatgt tccggggcaa tcttcagata
    22681 accgccaacg tgatgggtcg ccagctcttt gatatagcgc ggatcttcta cagcgatgtc
    22741 ataacgcaca ccagaggcaa tcaggatctt tttaatgcct ttcagatcac gcgcacggcg
    22801 atagagattg atggtcggtt catgattagt gtccatgtgc gaacaaatat ccggataaac
    22861 gcacgacaaa cgacggcagg tttgctcagc gcgtggcgat ttgcagcgca acatatacat
    22921 gttggcagta ggcccaccga gatcggaaat cacgcccgta aaacctggaa cagtgtcgcg
    22981 gatcgcttcg atctcattaa taatcgaatc ttcggaacgg ctctgaataa tgcgcccttc
    23041 gtgctcggta atagaacaga aagagcagcc gccaaagcag ccacgcataa tgttgaccga
    23101 gaaacgaatc atttcgtaag ccggaattcg ggcattaccg taagccggat gcggcacgcg
    23161 cttgtacggc agcgcaaaga cgctatccat ctcttcggta gaaagcggaa tagcaggcgg
    23221 gttgatccat acatagcggt cgccatgttt ttgcatcaat gcgcgggcgc agcctgggtt
    23281 agtttcgtgg tgcagaatgc gcgaagcatg ggcgtacagc actttatcgc ccttcacttt
    23341 ctcgaaagaa ggcagcaaca cgtaggtttt ttcccacggt ttcgggcgtg gtggctgcac
    23401 ggttacagat ttggcttcct gctttttcgg agctaccggt ttgttatccg cgcacggcaa
    23461 atcttcgcca tacggatgcg ggattgggtc gattttccca ggggtatcaa gacgggtgga
    23521 atccacaccg ctccagcctg gcaacgcctc ttttacgata atcgcggtat tacgcacatc
    23581 gcggatttca ctaatcggct cgcccatcgc cagacggtgc gccacttcca ccagcggacg
    23641 ctcaccgtta ccaaacatca gcatgtcggc tttcgaatcc accagcacgg aacggcgcac
    23701 ggtatccgac cagtaatcat agtgcgcggt acggcgcagg ctggcctcaa taccgccgag
    23761 gatcaccggc acatctttcc acgcctcttt acaacgttgg gtataaacca gtgtggcgcg
    23821 atccggacgc ttacccgcga cattatctgg cgtgtaggca tcgtcatgac gtaaacggcg
    23881 atcggcggta tagcggttga tcatcgagtc catgttgcca gcagtaacac cgaaaaacag
    23941 attcggttta cccagacgca taaagtcgtc tttgctgctc cagtctggct gggcgatgat
    24001 cccgacgcga aagccctgcg cttccagcat acgaccgcaa atcgccatcc cgaagcttgg
    24061 gtgatcgaca tacgcgtcgc cagtaaccaa aatgatgtcg cagctatccc agccaagttg
    24121 atccatctct tcacgtgaca tcggcaaaaa cggtgccggt ccaaaacagg cggcccagta
    24181 ctgcggccag gagaacaggt cgcgatccgg ttggatcagg gagatagagc tcattttgct
    24241 tccagaaatg gtaaaaaaat aatcaaaggc cggggattat acgctgtatc acgcgcggaa
    24301 atgaagtgat gttgatgaac ggtggcgaaa taccctggtg aggtttttca ctgcccgact
    24361 tgggcaagca catttaaggc tggcggtatc gtggcaactg ccgctactat ttatgccgat
    24421 cagcaacgtt caaatcatat tgcacgacga tcggctatcc gaggacaccc acagtaaggc
    24481 aaggtatgga acaggttatt acaaagcgcc gctattacga tattggtcta cagattgaag
    24541 agctgctgta ttcaggcgta ttcaaagccg gagaacgctt accttcagaa cgtgaactga
    24601 gcgagcggtt taataccagc cgaactacca ttcgtgaagc catcattatg ctggaactga
    24661 aaggcgtatt gaatgtgaag caagggtcag ggattttttt tgtcgactcc accgataagc
    24721 tcaaccagaa atcattaatg ccctattcag aaattggccc gtttgaactg ttgcaggcgc
    24781 gtcaggtgat tgagagcaat attactggtt ttgcagccag ccagattagc tttaacgagt
    24841 tacaagagtt aaagaaaatc attagtttgc aggaaaacgc tatcgctgcg gaaagtgata
    24901 gatttgaaga cctggatcat cgttttcata gcattattgc cgaagcgacg caaaatcggg
    24961 tactcatcaa acaagccgct gaattatggc gggcagtgcg tacagaaaac ccccgctgga
    25021 agaaacttaa ctacaagtac ctgcatgaaa agcatttgcg tctgcaatgg ctggaagatc
    25081 accgggctat tttcctggct ctgcaacaga aagattcaga gctcgccagg gaagcgtcct
    25141 ggagacatct ggaaaacagc aaaaatgaac tgatcaaaat cttcaaacaa gacgcttcca
    25201 tcagcgattt tgatgacttt ttcttcgctc gttaaccttc attagtccag agctggcggg
    25261 aaaaataacg ccggctctgc ctttcgccct ccactggtac acgctctctt tttaattggt
    25321 ctaataaatc gactatcatc agatatctta gattagcggc aattatccta aaaactgacc
    25381 tctaaaaaac tttcctttca ttttattcat ataactcatt gatacagata taaataacgc
    25441 cttgttgttc tgtttcgtac ttttaccttt ctctgcaagc gtgatgcatc tctctgtttt
    25501 tggtctagtg aattatgtaa attggtctac acacaagtcg tcaggagtaa gagcataatg
    25561 tcagggaacg aaagtatcgc tgccgcccac tatgatcagg taaccacctg gcctcgggac
    25621 gggttacagg cagatattgt ccatattggt tttggcgctt ttcatcgcgg acaccaggct
    25681 gtctacacgg atctcactaa tcaactttcg gacacccgct gggggatctt tgagatcaac
    25741 ctgtttggtg atgctcaact gatcgaaaac ttaaatgcgc aaaatgggct gttttcggtt
    25801 gtggaaacat ctgcatcgca atctacctca cgccttgtgc gttcggtggc tggcggtatt
    25861 cataccccca gagatggcat tgccgcagca atccataaac tggctgaacc tcaggtaaaa
    25921 atcgtttcat taaccatcac cgagaaaggt tattgcctcg atccgcaaac acgttcactt
    25981 gatctcacca atggattaat ccaacacgat ctacaaaacc cggatgcgcc tctgtcagct
    26041 attggcgtga tcgtctgtgc tttgcaacaa cgtaaagcgg caggactcgc cgcttttagt
    26101 gtgctctcct gtgacaactt gccagacaat gggcatctga cgcgcaatgc cgttctcggt
    26161 tttgcccgac aactggacca gcccctggct cagtggatcg aagaaaatgt ctcatttcca
    26221 ggcacgatgg tagatcgcat tgttccggca atgactgaat cgcaattcgc cttactggaa
    26281 acgaaaaccg gttatgccga tccctgcggg atcgtctgcg aatcatttcg tcagtgggtg
    26341 atcgaagata attttgtgcg cggacgaccg gaatgggata aagccggcgc gatgtttgtc
    26401 agcaatgttc agccttatga agagatgaag ttacgcatgt taaatggtag ccattcattt
    26461 ctggcttata acggctcttt ggcaggctat gagtttatct ggcaatgcat ggaagacgct
    26521 aattttcgtt ccattaccca ccaactgatg attaatgaac aagcccgaac acttaatcca
    26581 gacttaaata tcaacatcca ggaatacgcc gacctgttaa ttgaacgctt tagcaaccgt
    26641 aacgttgcgc accgtaccgg gcaaatagcc atggacggtt cacaaaagct tccccagcgt
    26701 gcactgacgc cctggctgaa attacatcag caaaagcaaa acaatgctgt tctgtcactg
    26761 ctcgttgctg gttggttgca ttatgtcatt gatgttgttg agaaaagcca gtctgtcgct
    26821 gatccaatga atgaccaatt t
//
LOCUS       DAPOXO010000071        26609 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.071, whole genome shotgun sequence.
ACCESSION   DAPOXO010000071 DAPOXO010000000
VERSION     DAPOXO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26609
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.071"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            20..1489
                     /gene="gspA"
                     /locus_tag="ROH59_003530"
     CDS             20..1489
                     /gene="gspA"
                     /locus_tag="ROH59_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspA"
                     /protein_id="HDX4805969.1"
                     /translation="MSTRREVILSWLREKHQTWRLCYLLGEAGSGKTRLAQQLQKDKH
                     RRVITLSLVVSWQGKAAWIVTDDNAAEQGCRDSAWTRDEMAGQLLHALHRTDSRCPLI
                     IIENAHLNHRRILDDLQRAISLIPDGQFLLIGRPDRKVERDFKKQGIELVSTGRLTEH
                     ELKASILEGQNIDQPDLLLTARVLKRIALLCRGDRRKLALAGETISLLQQAEQTCVFT
                     AKQWRMIYRVLGDNRPRKMQLAVVMSGTIIALTCGWLLLPSFTAPLPVPAWLIPVTPV
                     VKQDMTKDIAHVVMRDSEALSVLYGVWGYEVPADSAWCDQAVRAGLVCKSGNASLQTL
                     VDQNLPWIASLKVGDKKLPVVVVRVGDATVDVLVGQQTWTLTHKWFELVWTGDYLLLW
                     KMSPEGESTITRDSSEEEILWLETMLNRALHISTESSAEWRPLLVEKIKQFQKSHHLK
                     TDGVVGFSTLVHLWQVAGESAYLYRDEANISPETTVKGK"
     gene            1491..1910
                     /gene="gspB"
                     /locus_tag="ROH59_003531"
     CDS             1491..1910
                     /gene="gspB"
                     /locus_tag="ROH59_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative general secretion pathway protein GspB"
                     /protein_id="HDX4805970.1"
                     /translation="MFEFYIAAREQKETGHPGIFSRQKHSTIIYVICLLLICLWFAGM
                     VLVGGYARQLWALWIVKAEVTVDAETPAFKQSTQHYFFKKQPLPVVESVEEEDDPGVA
                     VENAPSSSEDEDNTVEESDEKAGLRERVKNALNELER"
     gene            2148..2459
                     /gene="rpsJ"
                     /locus_tag="ROH59_003532"
     CDS             2148..2459
                     /gene="rpsJ"
                     /locus_tag="ROH59_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDX4805971.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            2492..3121
                     /gene="rplC"
                     /locus_tag="ROH59_003533"
     CDS             2492..3121
                     /gene="rplC"
                     /locus_tag="ROH59_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDX4805972.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            3132..3737
                     /gene="rplD"
                     /locus_tag="ROH59_003534"
     CDS             3132..3737
                     /gene="rplD"
                     /locus_tag="ROH59_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDX4805973.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            3734..4036
                     /gene="rplW"
                     /locus_tag="ROH59_003535"
     CDS             3734..4036
                     /gene="rplW"
                     /locus_tag="ROH59_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDX4805974.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            4054..4875
                     /gene="rplB"
                     /locus_tag="ROH59_003536"
     CDS             4054..4875
                     /gene="rplB"
                     /locus_tag="ROH59_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDX4805975.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            4892..5170
                     /gene="rpsS"
                     /locus_tag="ROH59_003537"
     CDS             4892..5170
                     /gene="rpsS"
                     /locus_tag="ROH59_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDX4805976.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            5185..5517
                     /gene="rplV"
                     /locus_tag="ROH59_003538"
     CDS             5185..5517
                     /gene="rplV"
                     /locus_tag="ROH59_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDX4805977.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            5535..6236
                     /gene="rpsC"
                     /locus_tag="ROH59_003539"
     CDS             5535..6236
                     /gene="rpsC"
                     /locus_tag="ROH59_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDX4805978.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            6249..6659
                     /gene="rplP"
                     /locus_tag="ROH59_003540"
     CDS             6249..6659
                     /gene="rplP"
                     /locus_tag="ROH59_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDX4805979.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            6659..6850
                     /gene="rpmC"
                     /locus_tag="ROH59_003541"
     CDS             6659..6850
                     /gene="rpmC"
                     /locus_tag="ROH59_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDX4805980.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            6850..7104
                     /gene="rpsQ"
                     /locus_tag="ROH59_003542"
     CDS             6850..7104
                     /gene="rpsQ"
                     /locus_tag="ROH59_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDX4805981.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            7269..7640
                     /gene="rplN"
                     /locus_tag="ROH59_003543"
     CDS             7269..7640
                     /gene="rplN"
                     /locus_tag="ROH59_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDX4805982.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            7651..7965
                     /gene="rplX"
                     /locus_tag="ROH59_003544"
     CDS             7651..7965
                     /gene="rplX"
                     /locus_tag="ROH59_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDX4805983.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNATTGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            7980..8519
                     /gene="rplE"
                     /locus_tag="ROH59_003545"
     CDS             7980..8519
                     /gene="rplE"
                     /locus_tag="ROH59_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDX4805984.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            8534..8839
                     /gene="rpsN"
                     /locus_tag="ROH59_003546"
     CDS             8534..8839
                     /gene="rpsN"
                     /locus_tag="ROH59_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDX4805985.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            8873..9265
                     /gene="rpsH"
                     /locus_tag="ROH59_003547"
     CDS             8873..9265
                     /gene="rpsH"
                     /locus_tag="ROH59_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDX4805986.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            9278..9811
                     /gene="rplF"
                     /locus_tag="ROH59_003548"
     CDS             9278..9811
                     /gene="rplF"
                     /locus_tag="ROH59_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDX4805987.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            9821..10174
                     /gene="rplR"
                     /locus_tag="ROH59_003549"
     CDS             9821..10174
                     /gene="rplR"
                     /locus_tag="ROH59_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDX4805988.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            10189..10692
                     /gene="rpsE"
                     /locus_tag="ROH59_003550"
     CDS             10189..10692
                     /gene="rpsE"
                     /locus_tag="ROH59_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDX4805989.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            10696..10875
                     /gene="rpmD"
                     /locus_tag="ROH59_003551"
     CDS             10696..10875
                     /gene="rpmD"
                     /locus_tag="ROH59_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDX4805990.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            10879..11313
                     /gene="rplO"
                     /locus_tag="ROH59_003552"
     CDS             10879..11313
                     /gene="rplO"
                     /locus_tag="ROH59_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDX4805991.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            11321..12652
                     /gene="secY"
                     /locus_tag="ROH59_003553"
     CDS             11321..12652
                     /gene="secY"
                     /locus_tag="ROH59_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDX4805992.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            12684..12800
                     /gene="rpmJ"
                     /locus_tag="ROH59_003554"
     CDS             12684..12800
                     /gene="rpmJ"
                     /locus_tag="ROH59_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDX4805993.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            12947..13303
                     /gene="rpsM"
                     /locus_tag="ROH59_003555"
     CDS             12947..13303
                     /gene="rpsM"
                     /locus_tag="ROH59_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDX4805994.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            13320..13709
                     /gene="rpsK"
                     /locus_tag="ROH59_003556"
     CDS             13320..13709
                     /gene="rpsK"
                     /locus_tag="ROH59_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDX4805995.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADVVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            13743..14363
                     /gene="rpsD"
                     /locus_tag="ROH59_003557"
     CDS             13743..14363
                     /gene="rpsD"
                     /locus_tag="ROH59_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDX4805996.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            14389..15378
                     /gene="rpoA"
                     /locus_tag="ROH59_003558"
     CDS             14389..15378
                     /gene="rpoA"
                     /locus_tag="ROH59_003558"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDX4805997.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            15419..15802
                     /gene="rplQ"
                     /locus_tag="ROH59_003559"
     CDS             15419..15802
                     /gene="rplQ"
                     /locus_tag="ROH59_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDX4805998.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            15909..16277
                     /locus_tag="ROH59_003560"
     CDS             15909..16277
                     /locus_tag="ROH59_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HDX4805999.1"
                     /translation="MWLLDQWAERHIAEAQAKGEFDNLVGSGEPLILDDDSHVPPELR
                     AGYRLLKNAGCLPPELEHRREAIQLLDILKGIRHDDPQYQEVSRRLSLLELKLRQAGL
                     STDFLRGDYADKLLNKINDN"
     gene            16288..16713
                     /gene="zntR"
                     /locus_tag="ROH59_003561"
     CDS             16288..16713
                     /gene="zntR"
                     /locus_tag="ROH59_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HDX4806000.1"
                     /translation="MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQRSLQRLNDTCCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            16769..16987
                     /gene="arfA"
                     /locus_tag="ROH59_003562"
     CDS             16769..16987
                     /gene="arfA"
                     /locus_tag="ROH59_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor ArfA"
                     /protein_id="HDX4806001.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSDAC"
     gene            complement(16984..17397)
                     /gene="mscL"
                     /locus_tag="ROH59_003563"
     CDS             complement(16984..17397)
                     /gene="mscL"
                     /locus_tag="ROH59_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDX4806002.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLREAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAATPAPTKEEVLLTEIRDLLKEQNNRS"
     gene            complement(17527..18903)
                     /gene="trkA"
                     /locus_tag="ROH59_003564"
     CDS             complement(17527..18903)
                     /gene="trkA"
                     /locus_tag="ROH59_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HDX4806003.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            complement(18925..20214)
                     /gene="rsmB"
                     /locus_tag="ROH59_003565"
     CDS             complement(18925..20214)
                     /gene="rsmB"
                     /locus_tag="ROH59_003565"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDX4806004.1"
                     /translation="MKKQRNLRSMAAQAIEQVVEQGQSLSNILPPLQQKVSDKDKALL
                     QELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAET
                     VEGAVAIKRPQLKGLINGVLRQFHRQQDELLAEFNASDARYLHPSWLLKRLQKAYPEQ
                     WQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVQLETPAPVH
                     ALPGFEEGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVLAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRNPSQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQR
                     TADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
     gene            complement(20266..21213)
                     /gene="fmt"
                     /locus_tag="ROH59_003566"
     CDS             complement(20266..21213)
                     /gene="fmt"
                     /locus_tag="ROH59_003566"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDX4806005.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNIVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEDKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTTTKAAPGTILEANKQGIQVA
                     TGDGILNLLSMQPAGKKAMSVQDLLNSRREWFVPGNRLA"
     gene            complement(21228..21737)
                     /gene="def"
                     /locus_tag="ROH59_003567"
     CDS             complement(21228..21737)
                     /gene="def"
                     /locus_tag="ROH59_003567"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDX4806006.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            21867..22991
                     /gene="dprA"
                     /locus_tag="ROH59_003568"
     CDS             21867..22991
                     /gene="dprA"
                     /locus_tag="ROH59_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDX4806007.1"
                     /translation="MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLATTDYPGALFVEGEL
                     HALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            22963..23436
                     /locus_tag="ROH59_003569"
     CDS             22963..23436
                     /locus_tag="ROH59_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HDX4806008.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLSLET
                     REMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            23465..24007
                     /locus_tag="ROH59_003570"
     CDS             23465..24007
                     /locus_tag="ROH59_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HDX4806009.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACGYV
                     RPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGMFIGCSNYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPISAE"
     gene            24012..24584
                     /gene="tsaC"
                     /locus_tag="ROH59_003571"
     CDS             24012..24584
                     /gene="tsaC"
                     /locus_tag="ROH59_003571"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HDX4806010.1"
                     /translation="MNNNLQGDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKRRPVDKGLILIAANYEQLKPYIDDTMLTDAQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            24589..25407
                     /gene="aroE"
                     /locus_tag="ROH59_003572"
     CDS             24589..25407
                     /gene="aroE"
                     /locus_tag="ROH59_003572"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDX4806011.1"
                     /translation="METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLTPINDFI
                     NTLNTFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTD
                     GIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIHALGMHELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKG
                     KTPFLAWCEQRGSKRTADGLGMLVAQAAHAFLLWHGVLPDVEPVIKLLQQELSA"
     gene            25404..25661
                     /locus_tag="ROH59_003573"
     CDS             25404..25661
                     /locus_tag="ROH59_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HDX4806012.1"
                     /translation="MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRF
                     TGDTPEQWLESFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(25637..26191)
                     /locus_tag="ROH59_003574"
     CDS             complement(25637..26191)
                     /locus_tag="ROH59_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDX4806013.1"
                     /translation="MSEVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPAGNPLTIGEDVTIGHKVMLHGCTIGN
                     RVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYMDQGNHTQP"
BASE COUNT         6803 a         6265 c         6938 g         6603 t
ORIGIN      
        1 aattaaaaca ggaagttcta tgtctacgag aagagaagtc attctttcct ggttgcgtga
       61 gaagcatcag acctggcgtc tgtgctattt gttgggtgag gctggaagtg gaaaaacccg
      121 gctggcgcag caactacaaa aagataaaca tcgccgtgtg attactttaa gcctcgttgt
      181 ttcctggcaa ggtaaggccg catggatcgt taccgacgat aatgcggctg aacagggctg
      241 ccgtgacagc gcctggacgc gagatgagat ggcgggtcaa ttactgcatg cacttcatcg
      301 aactgatagt cgctgccctc ttattattat tgaaaatgct cacctgaatc accgccgcat
      361 acttgatgat ctccaacgcg cgatatctct tattcctgac ggtcaatttt tgctgatcgg
      421 cagacccgat cgaaaagtcg aacgtgattt taaaaaacag ggcattgaac ttgtctcgac
      481 aggtcgtctg acggagcacg agcttaaggc aagcatcctt gaaggtcaga atattgacca
      541 gcccgatctc cttttaaccg ccagagttct gaaacggata gctttattat gtcggggaga
      601 tcgcagaaag ctggcgcttg ccggcgaaac aattagctta ttacagcaag ccgagcagac
      661 ctgcgttttc actgcaaaac aatggcgaat gatttaccgc gtattaggtg ataaccgccc
      721 ccggaaaatg cagcttgccg tggtgatgag tggaaccatt atcgcactta cctgtggttg
      781 gctactgctg ccctctttca cagctccgtt acccgttcct gcgtggctga tacccgtaac
      841 gccagtagtt aaacaagata tgactaagga tattgcccat gtggtgatgc gcgatagtga
      901 ggcgctaagc gtgttatacg gcgtatgggg gtacgaggtc ccagccgatt cggcctggtg
      961 cgatcaggca gtaagagcgg ggctggtatg taaaagtggg aatgcttctt tacaaacatt
     1021 ggtagatcag aatttgccct ggatcgcatc gcttaaagtc ggggacaaaa aattgcctgt
     1081 tgtggtcgtt cgcgtcggtg atgctaccgt tgatgtactc gtagggcagc aaacctggac
     1141 gctgacacat aaatggtttg agttggtatg gacgggtgat tatcttctgt tgtggaaaat
     1201 gtcgccggaa ggagagagta ccattacgcg tgatagcagc gaggaagaga ttctctggct
     1261 ggaaacgatg ttaaaccgcg cattgcatat ttcgacagaa tcttcggcag agtggcgtcc
     1321 cttgttggta gaaaaaataa agcaatttca aaaaagccat cacttgaaaa ctgacggtgt
     1381 tgttggcttt tcaacgttag tgcatctctg gcaggtggca ggggagagtg cctacttata
     1441 tcgggatgaa gcaaatattt ccccggaaac aacagtgaag gggaaatgac atgtttgaat
     1501 tctatatcgc cgcgcgtgag cagaaagaaa caggtcaccc tggtatcttc tcccgacaaa
     1561 aacacagcac cataatatat gtcatttgtt tattgctgat ttgcctgtgg tttgcaggaa
     1621 tggtgttggt tggtgggtat gcccggcagc tatgggcact ttggatagta aaagcagaag
     1681 tcactgtaga tgctgaaacg cccgctttta aacaatcaac acaacactat tttttcaaaa
     1741 aacagccact ccccgtcgtc gaatccgtcg aggaggaaga tgacccagga gtcgcggttg
     1801 agaatgcccc ctcttcttct gaagacgaag acaatactgt agaagaaagc gacgagaaag
     1861 ccggtttaag agagcgtgtc aaaaatgcgc tgaacgaact tgagagataa cccaaaggct
     1921 gtttacttta ctagcaatac gcttgcgttc ggtggttaag tatgtataat gcgcgggctt
     1981 gtcgtagttg acagcaggtt caatctgaac ctcagttagc cgaatttggc tacctaacaa
     2041 tgctcccaat cggggagcta cgtaagaacg gttacactct cccatcaatc gtaatgggtc
     2101 tgaggagtaa tcattttcgt ttataaaata attggagctc tggtctcatg cagaaccaaa
     2161 gaatccgtat ccgcctgaaa gcgtttgatc atcgtctgat cgatcaagca accgcggaaa
     2221 tcgtcgagac tgctaagcgc actggtgcgc aggtccgtgg tccgatcccg ctgccgacac
     2281 gcaaagagcg cttcactgtt ctgatctccc cgcacgtcaa caaagacgcg cgcgatcagt
     2341 acgaaatccg tactcacttg cgtctggttg acatcgttga gccaaccgag aaaaccgttg
     2401 atgctctgat gcgtctggat ctggctgccg gtgtagacgt gcagatcagc ctgggttaat
     2461 caggtcattg agcgattgag aggttgaaac aatgattggt ttagtcggta aaaaagtggg
     2521 tatgacccgt atcttcacag aagacggcgt ttctatccca gtaaccgtaa tcgaagttga
     2581 agcaaaccgc gttactcagg ttaaagacct ggctaacgat ggctaccgtg ctattcaggt
     2641 gaccaccggt gctaaaaaag ctaaccgtgt gaccaagcct gaagctggcc acttcgctaa
     2701 agctggcgta gaagctggcc gtggtctgtg ggaattccgc ctggctgaag gcgaagagtt
     2761 cactgtaggt cagagcatta gcgttgaact gtttgctgac gttaaaaaag ttgacgtaac
     2821 tggcacctct aaaggtaaag gtttcgcagg taccgttaag cgctggaact tccgtaccca
     2881 ggacgctact cacggtaact ccttgtctca ccgcgttccg ggttctatcg gtcagaacca
     2941 gactccgggc aaagtgttca aaggcaagaa aatggcaggt cagatgggta acgaacgtgt
     3001 aaccgttcag agccttgacg tagtacgcgt tgacgctgag cgcaacctgc tgctggttaa
     3061 aggcgctgtc ccgggtgcaa ccggtagcga cctgatcgtt aaaccagctg tgaaggcgta
     3121 aggagatagc aatggaatta gtattgaaag acgcgcagag cgcgctgact gtttccgaaa
     3181 ctaccttcgg tcgtgatttc aacgaagcgc tggttcacca ggttgttgtt gcttatgcag
     3241 ctggtgctcg tcagggtact cgtgctcaga agactcgtgc tgaagtaact ggttccggta
     3301 aaaaaccgtg gcgccagaaa ggcaccggcc gtgcgcgttc tggttctatc aagagcccga
     3361 tctggcgttc tggtggcgtg acctttgctg ctcgtccgca ggaccacagt caaaaagtta
     3421 acaagaagat gtaccgcggc gcgctgaaaa gcatcctgtc cgaactggta cgtcaggatc
     3481 gtctgatcgt tgtcgagaag ttctctgtag aagcgccgaa aactaagctg ctggcacaga
     3541 aactgaaaga catggctctg gaagatgtgc tgatcatcac cggtgagctg gacgagaacc
     3601 tgttcctggc tgcgcgcaac ctgcacaagg ttgacgtacg cgatgcaact ggtatcgacc
     3661 cggttagcct gatcgccttc gacaaagtcg taatgactgc tgatgctgtt aagcaagttg
     3721 aggagatgct ggcatgattc gtgaagaacg tctgctgaag gtgctgcgtg caccgcacgt
     3781 ttctgaaaaa gcgtctactg cgatggaaaa atccaacacc atcgtactca aagttgctaa
     3841 agacgcgacc aaagcagaaa tcaaagctgc tgtgcagaaa ctgtttgaag tcgaagtcga
     3901 agtcgttaac accctggtag ttaaagggaa agttaaacgt cacggacagc gtatcggtcg
     3961 tcgtagcgac tggaaaaaag cttacgtcac cctgaaagaa ggccagaatc tggacttcgt
     4021 tggcggcgct gagtaagtcg gaggagtaat acaatggcag ttgttaaatg taaaccgaca
     4081 tctccgggtc gtcgccacgt agttaaagtg gttaaccctg agctgcacaa gggcaaacct
     4141 tttgctccgt tgctggaaaa aaacagcaaa tccggtggtc gtaacaacaa tggccgtatc
     4201 accactcgtc atatcggtgg tggccacaag caggcttacc gtattgttga cttcaaacgc
     4261 aacaaagacg gtatcccggc agttgttgaa cgtcttgagt acgatccgaa ccgttccgcg
     4321 aacatcgcgc tggttctgta caaagacggt gaacgccgtt acatcctggc ccctaaaggc
     4381 ctgaaagctg gcgaccagat tcagtctggc gttgatgctg caatcaaacc aggtaacacc
     4441 ctgccgatgc gcaacatccc ggttggttct actgttcata acgtagaaat gaaaccaggt
     4501 aaaggcggtc agctggcacg ttccgctggt acttacgttc agatcgttgc tcgtgatggt
     4561 gcttatgtca ccctgcgtct gcgttctggt gaaatgcgta aagtagaagc agactgccgt
     4621 gcaactctgg gcgaagttgg caatgctgag catatgctgc gcgttctggg taaagcaggt
     4681 gctgcacgct ggcgtggtgt tcgtccgacc gttcgcggta ccgcgatgaa cccggtagac
     4741 cacccacatg gtggtggtga aggtcgtaac tttggtaagc acccggtaac tccgtggggc
     4801 gttcagacca aaggtaagaa gacccgcagc aacaagcgta ctgataaatt catcgtacgt
     4861 cgccgtagca aataatttta gaggataagc catgccacgt tctctcaaga aaggtccttt
     4921 tattgacctg cacttgctga agaaggtaga gaaagcggtg gaaagcggag acaagaagcc
     4981 cctgcgcact tggtcccgtc gttcaacgat ctttcctaac atgatcggtt tgaccatcgc
     5041 tgtccataat ggtcgtcagc acgttccggt atttgtaacc gacgaaatgg tcggtcacaa
     5101 actgggtgaa ttcgcaccga ctcgtactta tcgcggccac gctgctgata aaaaagcgaa
     5161 gaagaaataa ggtaggagga agagatggaa actatcgcta aacatcgcca tgctcgttct
     5221 tctgctcaga aggttcgcct tgttgctgac ctgattcgcg gtaagaaagt gtcgcaggct
     5281 ctggatattt tgacctacac caacaagaaa gcggctgtac tggtcaagaa agttctggaa
     5341 tctgccattg ctaacgctga acacaacgat ggcgctgaca ttgacgatct gaaagttacg
     5401 aaaattttcg tagacgaagg cccgagcatg aagcgcatta tgccgcgtgc aaaaggtcgt
     5461 gcagatcgca tcctgaagcg caccagccac atcactgtgg ttgtgtccga tcgctgagac
     5521 tctggagact agcaatgggt cagaaagtac atcctaatgg tattcgcctg ggtattgtaa
     5581 aaccatggaa ctctacctgg tttgcgaaca ccaaagaatt cgctgacaac ctggacagcg
     5641 attttaaagt acgtcagtac ctgactaagg aactggctaa agcgtccgta tctcgtatcg
     5701 ttatcgagcg tccggctaag agcatccgtg taaccattca cactgctcgc ccgggtatcg
     5761 ttatcggtaa aaaaggtgaa gacgtagaaa aactgcgtaa ggtcgtagcg gacatcgctg
     5821 gcgttcctgc acagatcaac atcgccgaag ttcgtaagcc tgaactggac gcaaaactgg
     5881 ttgctgacag catcacttct cagctggaac gtcgcgttat gttccgtcgt gctatgaagc
     5941 gtgctgtaca gaacgcaatg cgtctgggcg ctaaaggtat taaagttgaa gttagcggcc
     6001 gtctgggcgg cgcggaaatc gcacgtaccg aatggtaccg cgaaggtcgc gtaccgctgc
     6061 acactctgcg tgctgacatc gactacaaca cctctgaagc gcacaccact tacggtgtaa
     6121 tcggcgttaa agtgtggatc ttcaaaggcg agatcctggg tggtatggct gctgttgaac
     6181 aaccggaaaa accggctgct cagcctaaaa agcagcagcg taaaggccgt aaataaggag
     6241 cgtcgctgat gttacaacca aagcgtacaa aattccgtaa aatgcacaaa ggccgtaacc
     6301 gcggtctggc gcagggtacg gatgttagct tcggcagctt cggtctgaaa gctgttggcc
     6361 gtggtcgtct gactgcacgt cagatcgaag cagcacgtcg tgctatgacc cgtgcagtta
     6421 agcgtcaagg taagatctgg atccgtgtgt tcccggacaa accgatcact gaaaagccgc
     6481 tggcagtgcg tatgggtaaa ggtaaaggta acgtggagta ttgggttgcc ttgattcagc
     6541 cgggtaaagt cctgtatgaa atggacggtg ttccggaaga gctggcccgt gaagcattca
     6601 agctggcagc agcgaaactg ccgattaaaa ccacctttgt aactaagacg gtgatgtaat
     6661 gaaagcaaaa gagctgcgtg agaagagcgt tgaagagctg aacaccgagc tgctgaacct
     6721 gctgcgtgag cagttcaacc tgcgtatgca ggctgcaagt ggccagctgc aacagtctca
     6781 cctgttgaag caagtgcgtc gcgatgtcgc acgcgttaag actttactga acgagaaggc
     6841 gggtgcgtaa tgaccgataa aatccgtact ctgcaaggtc gcgttgttag cgacaaaatg
     6901 gagaaatcca ttgttgttgc tatcgaacgt tttgtgaaac acccgatcta cggtaaattc
     6961 atcaagcgta cgaccaaact gcacgtacat gacgagaaca acgaatgcgg tatcggtgac
     7021 gtggttgaaa tccgcgaatg ccgtccgctg tccaagacta aatcctggac gctggttcgc
     7081 gttgtagaga aagcggttct gtaatacagt acactctctc gatacgaata aacggctcag
     7141 aaatgagccg tttatttttt ctacccatat ccttgaagcg gtgttataat gccgcgccct
     7201 cgatatgggg atttttaacg acctgatttt cgggtctcag tagtagttga cattagcgga
     7261 gcactaaaat gatccaagaa cagactatgc tgaacgtcgc cgacaactcc ggtgcacgtc
     7321 gcgtaatgtg tatcaaggtt ctgggtggct cgcaccgtcg ctacgcaggc gtaggcgata
     7381 tcatcaagat caccatcaaa gaagcaattc cgcgtggtaa ggtcaaaaaa ggtgatgtgc
     7441 tgaaggcggt agtggtgcgc accaagaagg gtgttcgtcg cccggacggt tctgtcattc
     7501 gcttcgatgg taatgcttgt gttcttctga acaacaacag cgagcagcct atcggtacgc
     7561 gtatttttgg gccggtaact cgtgagcttc gtagtgagaa gttcatgaaa attatctctc
     7621 tggcaccaga agtactctaa ggagcgaatc atggcagcga aaatccgtcg tgatgacgaa
     7681 gttatcgtgt taaccggtaa agataaaggt aaacgcggta aagttaagaa tgtcctgtct
     7741 tccggcaagg tcattgttga aggtatcaat ctggttaaga aacatcagaa gccggttccg
     7801 gccctgaacc aaccgggtgg catcgttgaa aaagaagccg ctattcaggt ttccaacgta
     7861 gcaatcttca atgcgacaac cggcaaggct gaccgtgtag gctttagatt cgaagacggt
     7921 aaaaaagtcc gtttcttcaa gtctaacagc gaaactatca agtaatttgg agtagtacga
     7981 tggcgaaact gcatgattac tacaaagacg aagtagttaa aaaactcatg actgagttta
     8041 actacaattc tgtcatgcaa gtccctcggg tcgagaagat caccctgaac atgggtgttg
     8101 gtgaagcgat cgctgacaaa aaactgctgg ataacgcagc agcagacctg gcagcaatct
     8161 ccggtcaaaa accgctgatc accaaagcac gcaaatctgt tgcaggcttc aaaatccgtc
     8221 agggctatcc gatcggctgt aaagtaactc tgcgtggcga acgcatgtgg gagttctttg
     8281 agcgcctgat cactattgct gtacctcgta tccgtgactt ccgtggcctg tccgctaagt
     8341 ctttcgacgg tcgtggtaac tacagcatgg gtgtccgtga gcagatcatc ttcccagaaa
     8401 tcgactacga taaagtcgac cgcgttcgtg gtttggatat taccattacc actactgcga
     8461 aatctgacga agaaggccgc gctctgctgg ctgcctttga cttcccgttc cgcaagtaag
     8521 gtagggttac taaatggcta agcaatcaat gaaagcacgc gaagtaaaac gcgtagcttt
     8581 agctgataaa tacttcgcga aacgcgctga actgaaagcg atcatctctg atgtgaacgc
     8641 ttccgacgaa gatcgttgga acgctgttct caagctgcag actctgccgc gtgattccag
     8701 cccgtctcgt cagcgtaacc gctgccgtca aacaggtcgt ccgcatggtt tcctgcggaa
     8761 gttcgggttg agccgtatta aggtccgtga agccgctatg cgcggtgaaa tcccgggtct
     8821 gaaaaaggct agctggtaat tgtcaccaat tgaatcacgg gagtaaagac agatgagcat
     8881 gcaagatccg atcgcggata tgctgacccg tatccgtaac ggtcaggccg cgaacaaagc
     8941 tgcggtcacc atgccttcct ccaagctgaa agtggcaatc gccaacgtgc tgaaggaaga
     9001 aggttttatt gaagatttta aagttgaagg cgacaccaag cctgaactgg aacttactct
     9061 gaagtatttc cagggcaaag ctgttgtaga aagcattcag cgtgtcagcc gcccaggtct
     9121 gcgcatctat aaacgtaaag atgagctgcc gaaagttatg gcgggtctgg gtatcgcagt
     9181 tgtttctacc tctaaaggtg ttatgactga tcgtgcagcg cgccaggctg gtcttggtgg
     9241 cgaaattatc tgctacgtag cctaatcgga ggaaaaaatg tctcgtgttg ctaaagcacc
     9301 ggtcgttgtt cctgccggcg ttgacgtaaa aatcaacggt caggttatta cgatcaaagg
     9361 taaaaacggc gagctgactc gtactctcaa cgatgctgtt gaagttaaac atgcagataa
     9421 taccctgacc ttcggtccgc gtgatggtta cgcagacggt tgggcacagg ctggtaccgc
     9481 gcgtgccctg ctgaactcaa tggttatcgg tgttaccgaa ggcttcacta agaagctgca
     9541 gctggttggt gtaggttacc gtgcagcggt taaaggcaat gtgattaacc tgtctctggg
     9601 tttctctcat cctgttgacc atcagctgcc tgcgggtatc actgctgaat gtccgactca
     9661 gactgaaatc gtgctgaaag gcgctgataa gcaggtgatc ggccaggttg cagcggatct
     9721 gcgcgcctac cgtcgtcctg agccttacaa aggcaagggt gttcgttacg ccgacgaagt
     9781 cgtgcgtacc aaagaggcta agaagaagta aggtaacact atggataaga aatctgctcg
     9841 tatccgtcgt gcgacccgcg cacgccgcaa gctccaggag ctgggcgcaa ctcgcctggt
     9901 ggtacatcgt accccgcgtc acatttacgc acaggtaatt gcaccgaacg gttctgaagt
     9961 tctggtagct gcttctactg tagaaaaagc tatcgctgaa caactgaagt acaccggtaa
    10021 caaagacgcg gctgcagctg tgggtaaagc tgtcgctgaa cgcgctctgg aaaaaggcat
    10081 caaagatgta tcctttgacc gttccgggtt ccaatatcat ggtcgtgtcc aggcactggc
    10141 agatgctgcc cgtgaagctg gccttcagtt ctaaggtaga ggtgtaagat ggctcacatc
    10201 gaaaaacaag ctggcgaact gcaggaaaag ctgatcgcgg taaaccgcgt atctaaaacc
    10261 gttaaaggtg gtcgtatttt ctccttcaca gctctgactg tagttggcga tggtaacggt
    10321 cgcgttggtt ttggttacgg taaagcgcgt gaagttccag cagcgatcca gaaagcgatg
    10381 gaaaaagccc gtcgcaatat gattaacgtc gcgctgaata acggcactct gcaacaccct
    10441 gttaaaggtg ttcacacggg ttctcgcgta ttcatgcagc cggcttccga gggtaccggt
    10501 atcatcgccg gtggtgcaat gcgcgccgtt ctggaagtcg ctggggttca taacgttctg
    10561 gctaaagcgt atggttccac caacccgatt aacgtggttc gtgcaactat cgatggcctg
    10621 gaaaatatga attctccaga aatggtcgct gccaagcgtg gtaaatccgt tgaagaaatt
    10681 ctggggaaat aaaccatggc aaagactatt aaaattactc aaacccgcag tgcaatcggt
    10741 cgtctgccga aacacaaggc aacgctgctt ggcctgggtc tgcgtcgtat tggtcacacc
    10801 gtagagcgcg aggatactcc tgctattcgc ggtatgatca acgcggtttc cttcatggtt
    10861 aaagttgagg agtaagagat gcgtttaaat actctgtctc cggccgaagg ctccaaaaag
    10921 gcgggtaaac gcctgggtcg tggtatcggt tctggcctcg gtaaaaccgg tggtcgtggt
    10981 cacaaaggtc agaaatctcg ttctggcggt ggcgtacgtc gcggtttcga gggtggtcag
    11041 atgcctctgt accgtcgtct gccgaaattc ggcttcactt ctcgtaaagc agcgattaca
    11101 gccgaagttc gtctgtctga cctggctaaa gtagaaggcg gtgttgtaga cctgaacacg
    11161 ctgaaagcgg ctaacattat cggtatccag atcgagttcg cgaaagtgat cctggctggc
    11221 gaagtaacga ctccggtaac tgttcgtggc ctgcgtgtta ctaaaggcgc tcgtgctgct
    11281 atcgaagctg ctggcggtaa aatcgaggaa taagtagcag atggctaaac aaccgggatt
    11341 agattttcaa agtgccaaag gtggcttagg cgagctgaaa cgcagactgc tgtttgttat
    11401 cggtgcgctg attgtgttcc gtattggctc ttttattccg atccctggta ttgatgccgc
    11461 tgtacttgcc aaactgcttg agcaacagcg aggcaccatc attgagatgt ttaacatgtt
    11521 ctctggtggt gctctcagcc gtgcttctat ctttgctctg gggatcatgc cgtatatttc
    11581 ggcgtcgatc attatccagc tactgacggt ggttcatcca acgttggcag aaattaagaa
    11641 agaaggggag tctggtcgtc gtaagatcag ccagtacacc cgctacggta ctctggtgct
    11701 ggcaatattc cagtcgatcg gtattgctac tggtctgccg aatatgcctg gtatgcaagg
    11761 cctggtgatt aacccgggct ttgcattcta cttcaccgct gttgtaagtc tggtcacagg
    11821 aaccatgttc ctgatgtggt tgggcgaaca gatcactgaa cgaggtatcg gcaacggtat
    11881 ttcaatcatt atcttcgccg gtattgtcgc gggactcccg ccagccattg cccatactat
    11941 cgagcaagcg cgtcaaggcg acctgcactt cctcgtgttg ctgttggttg cagtattagt
    12001 atttgcagtg acgttctttg ttgtatttgt tgagcgtggt caacgccgca ttgtggtaaa
    12061 ctacgcgaaa cgtcagcaag gtcgtcgtgt ctatgctgca cagagcacac atttaccgct
    12121 gaaagtgaat atggcggggg taatcccggc aatcttcgct tccagtatta ttctgttccc
    12181 ggcgaccatc gcgtcatggt tcgggggcgg tactggttgg aactggctga caacaatttc
    12241 gctgtatttg cagcctgggc aaccgcttta tgtgttactc tatgcgtctg caatcatctt
    12301 cttctgtttc ttctacacgg cgttggtttt caacccgcgt gaaacagcag ataacctgaa
    12361 gaagtccggt gcatttgtac caggaattcg tccgggagag caaacggcga agtatatcga
    12421 taaagtaatg acccgcctga ccttggttgg tgcgctgtac attaccttta tctgcctgat
    12481 cccggagttc atgcgtgatg caatgaaagt accgttctac ttcggtggga cctcactgct
    12541 tatcgttgtt gtcgtgatta tggactttat ggctcaagtg caaactctga tgatgtccag
    12601 tcagtatgag tctgcattga agaaggcgaa cctgaaaggc tacggccgat aattggtcgc
    12661 ccgagaagtt acggagagta aaaatgaaag ttcgtgcttc cgtcaagaaa ttatgccgta
    12721 actgcaaaat cgttaagcgt gatggtgtca tccgtgtgat ttgcagtgcc gagccgaagc
    12781 ataaacagcg ccaaggctga ttttttcgca tatttttctt gcaaagttgg gttgagctgg
    12841 ctagattagc cagccaatct tttgtatgtc tgtgcgtttc catttgagta tcctgaaaac
    12901 gggcttttca gcatggaacg tacatattaa atagtaggag tgcatagtgg cccgtatagc
    12961 aggcattaac attcctgatc ataagcatgc cgtaatcgca ttaacttcga tttatggcgt
    13021 cggcaagacc cgttctaaag ccatcctggc tgcagcgggt atcgctgaag atgttaagat
    13081 cagtgagctg tctgaaggac aaatcgacac gctgcgtgac gaagttgcca aatttgtcgt
    13141 tgaaggtgat ctgcgccgtg aaatcagcat gagcatcaag cgcctgatgg atcttggttg
    13201 ctatcgcggt ttgcgtcatc gtcgtggtct cccggttcgc ggtcagcgta ccaagaccaa
    13261 cgcacgtacc cgtaagggtc cgcgcaaacc gatcaagaaa taatcggggt gattgaataa
    13321 tggcaaaggc accaattcgt gcacgtaaac gtgtaagaaa acaagtctct gacggcgtgg
    13381 ctcatatcca tgcttctttc aacaacacca tcgtgactat cactgatcgt cagggtaacg
    13441 cgttgggttg ggcaacagcc ggtggttccg gtttccgtgg ttctcgcaaa tccactccgt
    13501 ttgcagcaca ggttgcagca gagcgttgcg ctgacgtcgt gaaagaatac ggcatcaaga
    13561 atctggaagt tatggttaaa ggtccgggtc caggccgcga atctactatt cgtgctctga
    13621 acgccgcagg tttccgcatc actaacatta ctgatgtgac tccgatccct cataacggtt
    13681 gtcgtccgcc gaaaaaacgt cgcgtataac gcctcgtttt ccaggtttgt tggagaaaga
    13741 aaatggcaag atatttgggt cctaagctca agctgagccg tcgtgagggc accgacttat
    13801 tccttaagtc tggcgttcgc gcgatcgata ccaagtgtaa aattgaacaa gctcctggcc
    13861 agcacggtgc gcgtaaaccg cgtctgtctg actatggtgt gcagttgcgt gaaaagcaaa
    13921 aagttcgccg tatctatggt gtgctggagc gtcagttccg taactactac aaagaagcag
    13981 cacgtctgaa aggcaacacc ggtgaaaacc tgttggctct gctggaaggt cgtctggaca
    14041 acgttgtata ccgtatgggc ttcggtgcca ctcgtgcaga agcacgtcag ctggttagcc
    14101 ataaagcaat tatggtaaac ggtcgtgttg ttaacatcgc ttcttatcag gttagtccga
    14161 atgacgttgt aagcattcgt gagaaagcga agaagcagtc tcgcgtgaaa gccgctctgg
    14221 agctggctga gcagcgtgaa aagccaacct ggctggaagt tgatgctggc aagatggaag
    14281 gtacgtttaa gcgtaagccg gagcgttctg atctgtctgc ggacattaac gaacacctga
    14341 tcgtcgagct ttactccaag taaagcttag taccaaagag aggacacaat gcagggttct
    14401 gtgacagagt ttctaaaacc gcgcctggtt gatatcgagc aagtgagttc gacgcacgcc
    14461 aaggtgaccc ttgagccttt agagcgtggc tttggccata ctctgggtaa cgcactgcgc
    14521 cgtattctgc tctcatcgat gccgggttgc gcggtgaccg aggttgagat tgatggtgta
    14581 ctacatgagt acagcaccaa agaaggcgtt caggaagata tcctggaaat cctgctcaac
    14641 ctgaaagggc tggcggtgag agttcagggc aaagatgaag ttattcttac cttgaataaa
    14701 tctggcattg gccctgtgac tgcagccgat atcacccacg acggtgatgt cgaaatcgtc
    14761 aagccgcagc acgtgatctg ccacctgacc gatgagaacg cgtctattag catgcgtatc
    14821 aaagttcagc gcggtcgtgg ttatgtgccg gcttctaccc gaattcattc ggaagaagat
    14881 gagcgcccaa tcggccgtct gctggtcgac gcatgctaca gccctgtgga gcgtattgcc
    14941 tacaatgttg aagcagcgcg tgtagaacag cgtaccgacc tggacaagct ggtcatcgaa
    15001 atggaaacca acggcacaat cgatcctgaa gaggcgattc gtcgtgcggc aaccattctg
    15061 gctgaacaac tggaagcttt cgttgactta cgtgatgtac gtcagcctga agtgaaagaa
    15121 gagaaaccag agttcgatcc gatcctgctg cgccctgttg acgatctgga attgactgtc
    15181 cgctctgcta actgccttaa agcagaagct atccactata tcggtgatct ggtacagcgt
    15241 accgaggttg agctccttaa aacgcctaac cttggtaaaa aatctcttac tgagattaaa
    15301 gacgtgctgg cttcccgtgg actgtctctg ggcatgcgcc tggaaaactg gccaccggca
    15361 agcatcgctg acgagtaacc ggatcacagg ttaaggtttt actgagaagg ataaggtcat
    15421 gcgccatcgt aagagtggtc gtcaactgaa ccgcaacagc agccatcgcc aggctatgtt
    15481 ccgcaatatg gcaggttcac tggttcgtca tgaaatcatc aagacgactc tgcctaaagc
    15541 gaaagagctg cgccgcgtag ttgagccgct gattactctt gccaagactg atagcgttgc
    15601 taatcgtcgt ctggcattcg cccgtactcg tgataacgag atcgtggcaa aactgtttaa
    15661 cgaactgggc ccgcgtttcg cgagccgtgc cggtggttac actcgtattc tgaagtgtgg
    15721 cttccgtgca ggcgacaatg cgccgatggc ttacatcgag ctggttgatc gttcagagaa
    15781 agcagaagct gctgcagagt aatctgaagc aacgtaaaaa aacccgcccc ggcgggtttt
    15841 tttatacccg tagcatcccc acttatctag aatagctgta ctctttttgt tcatcccctg
    15901 gagtatttat gtggttactt gaccagtggg cagagcgtca tatagcagaa gcgcaagcga
    15961 aaggtgagtt tgataacctg gtaggtagcg gcgaaccatt gatactggat gatgattctc
    16021 atgtgccacc ggaattacgt gcggggtatc gcttgctgaa gaatgctggt tgcttaccgc
    16081 cagaacttga gcataggagg gaagcaatac agcttctgga tattctcaaa ggtatccgtc
    16141 atgatgatcc gcaatatcaa gaggttagtc gtcgattgtc attactggaa ttgaagctgc
    16201 gacaagctgg attgagtacc gattttttac gcggcgatta tgctgacaag ttgttgaaca
    16261 aaatcaacga taactagtgg agtatgtatg tatcgcattg gtgagctggc aaaaatggcg
    16321 gaagtaacac ccgacacgat tcgttattac gaaaagcagc agatgatgga gcatgaagta
    16381 cgcaccgaag gtgggtttcg cctgtatacc gaaagcgatc tccagcgatt gaaatttatc
    16441 cgccatgcca gacaactagg tttcagtctg gagtcgatcc gcgagttgct gtcgatccgt
    16501 atcgatcctg aacaccatac ctgtcaggag tcaaaaggca ttgtgcagga aagattgcag
    16561 gaagtcgaag ctcgtatagc cgagttgcag agtatgcagc gttccttgca acgccttaat
    16621 gatacctgtt gtgggaccgc ccatagcagt gtttattgct cgattcttga agctcttgaa
    16681 caaggggcga gtggcgttaa gagtggctgt tgattttttg cactggcagg attacactcg
    16741 cgccgttaaa taaccaattg gagtttttat gagccgatat cagcatacta aagggcagat
    16801 aaaggataat gcgatagaag cattactaca tgatccctta ttccgacagc gagtagagaa
    16861 aaataagaaa gggaaaggca gttacatgcg aaaaggaaaa catggcaatc gggggaactg
    16921 ggaggccagt ggcaagaaag taaatcactt ttttaccact ggccttctgc tttcagacgc
    16981 ttgttaagag cggttattct gctctttcag caaatcacga atttctgtca gtaatacttc
    17041 ttctttagtt ggtgcaggtg ttgctgctgc tggttcttct tttttccgat tcagtttgtt
    17101 gattagctta atcgccataa agatggcaaa ggccactatc agaaaatcaa agacgttttg
    17161 aatgaagaca ccgtaatgca tcacaacagc agggatatcc ccttgggcct cgcgtagcgt
    17221 gacagcaaac tgtttaaagt cgatcccgcc aattaataag cccagaggtg gcatgatgat
    17281 atcggcaacc agtgaagata caatcttccc gaatgccgct ccgataatga cacccactgc
    17341 caaatccacc acgttcccgc gcatcgcaaa ttcgcgaaat tctttaataa tgctcatgtt
    17401 attctcccta tgaagccgac aaccataagt ctaacaaatg ttaagccatt ttcctgccag
    17461 gaatggattt aattaatcct taataatcaa agggaaataa taaggcgtca ttagacgcct
    17521 tattaattac aagaagaaag gacttggctg gaagagtctt tcgacgtcgg taataaactt
    17581 tttatctgtg aggaacataa ttacgtgatc gccttgctca atgcgcagat tgtcattggc
    17641 aatcatcaca tcgtttccac gtaccaccgc tccaataatc gttcctggcg gtagcttgat
    17701 ttcgtcaatg actctgccga caacgcgtga ggtgctttca tcaccgtgag caacggcttc
    17761 aatagcttct gctacgccgc ggcgtaatga ggaaacacca acaatatctg cttttcgcac
    17821 atggctaagc aacgcagaaa tagttgcttg ttgtggtgaa atcgcaatat cgatcacgct
    17881 cccctgaacc agatccacat aagcgcgacg ttggatcaat accatcacct ttttcgcacc
    17941 catacgtttg gcaagcatgg cggacatgat attggcctcg tcatcgttgg tgacggcaat
    18001 aaacagatca acttgatcga tatgttcttc ggccagcagt tcttgatccg acgcatcacc
    18061 aaaaaagacg atcgtattct gcaacttttc cgccagttcg gcagcgcgct gctgattacg
    18121 ttcgatgagt ttaacgctgt aatctttttc cagacgacgc gccagccctg caccgatatt
    18181 accgccacca accagcatga tccgcttata cggtttttcc agtcgctgta attcactcat
    18241 caccgcacgg atatgctgtg aagcggcaat aaagaacact tcatcaccag cttcaacaat
    18301 ggtcgaacct tgcggacgaa tggggcgatc gtggcggaaa attgctgcca cacgagtatc
    18361 gatatgtggc atatgttcgc gcatggtcga aagtgcatta ccaatcagcg ggccgccata
    18421 ataggcttta accacagcca ggctgacttt accctcagcg aagttcacca cctgcaatgc
    18481 gccgggatac tcaatcagtc ggtaaatatt atcgataacc aactgctctg gtgcgatcag
    18541 atgatcaatc ggtacagcat ctgaatgaaa tagtttatcg gcatcgcgca cgtagtctgg
    18601 tgagcggata cgagcgatgc gattaggggt gttgaaaagt gagtaggcta cctggcaggc
    18661 aaccatattg gtttcatctg aactggttac agcaaccagc atatcggcgt cgtcggcacc
    18721 tgcctcccgc aatacgcgtg gatgagagcc atgcccctgc acgacccgca ggtcaaattt
    18781 atcctgtaag gtccgcagac gctcaccgtt ggtatcgaca acagtaatat cgttgttctc
    18841 gccaaccagg ttttccgcca gtgtgccgcc aacctggccg gcacccagaa tgataatttt
    18901 catcagtcgc gacccgttat ctcatcactt tttgattagc ttagcgtaaa agaagccgtc
    18961 gccctcttcg gcaccgggca aattttgttt acccggttgc tctggtgttc ctgtttcaca
    19021 aagttcggca tcagcggtac gttgcaaaaa ggctttaatc tgcaggctat tttcttccgg
    19081 taacaccgaa caggtggcat agaccagggt tccaccggat tttaaatgtg gccaaatggc
    19141 atcgagtatt tcagactgca attgcgcgag ttccgggata tcgcgatcac gacgtaacca
    19201 tttaatatcc ggatggcgac gaatcacccc cgttgctgaa caaggcgcat ctaataaaat
    19261 gcgatcaaac tgttgctcgc cacaccattg ggaagggttg cggccatcac cttgtttcac
    19321 ggtcgccttc ataccaaggc gttttaaatt gtcgtaaacg cgagagaggc gctgctcatc
    19381 aatatcgacc gccagaactt gcgcctctgg agcaacctca agaatatgcg ttgttttacc
    19441 gcctggggcg gcgcaaagat ccagaatgtg ttcaccattt tgtggagcaa gccaggtcat
    19501 gcaaccttgt gctgaagcat cctgaacggt aacccatcct tcttcaaaac cgggtagcgc
    19561 atgaacaggt gcaggtgttt ccagctgtac agcatcaggg taatccgcat gcgggaaacc
    19621 tttcattcct gcttcatcca gcaatgcaag ccagctgtcg cgggaatgat gcgtacgatt
    19681 aacgcgcagc cacattggcg gacgctggtt attggcttcg acgatggatt gccactgctc
    19741 gggatacgcc ttttgcagac gcttcagcaa ccaggaagga tgcagataac gtgcatcact
    19801 ggcattaaac tcggctaata actcatcttg ctgacgatgg aactgacgta atacaccgtt
    19861 aatcaatccc ttaagttgcg ggcgcttaat tgcaactgcg ccttcaaccg tttcagccag
    19921 cgcggcatga ggtggaatgc gggtataaag cagttgatac aaaccaacca taatcaggta
    19981 atgaacagta cgctgtttgc ctgtcatcgg acgggccatt agcttattaa tcagccagtc
    20041 taactgtgag agcgtacgca gtacgccaaa gcataactcc tggagaagag ctttatcttt
    20101 atcggaaact ttttgctgga gcggtggcag aatgttgctc agtgattgcc cttgctcaac
    20161 gacttgttca atggcctggg ccgccatgct acgtaaatta cgttgttttt tcataagtat
    20221 aaatataaag atgcccggta agaccgggct tagaagagtg gactatcagg ccagacggtt
    20281 gcccggtaca aaccattccc gacgagaatt caggaggtct tgcacgctca tcgctttctt
    20341 acctgcaggt tgcattgaga gcagattcag gatgccatca cctgtcgcta cctgaatgcc
    20401 ttgtttattg gcttcaagga ttgttcctgg cgcagccttt gttgtcgtat cgatgacaga
    20461 tgctttccag actttaaccg gctgcccttc aatttccagc cagctcattg gccatggatt
    20521 gaaagcgcga atgcaacgtt caagctgtgc tgccgaaagt gaccagtcaa tacgcgcttc
    20581 ttctttactc aacttttcgg cgtaagtgac aagagtttcg tcctgaactt ctggtttcgc
    20641 cgtgccgtct gccagttgtt tcaacgtggt gataagccct tgtgggccaa gctctgccag
    20701 cttgtcgtac agcgtaccac tggtatcttc tgcagtaatc gggcaggaga gcttatagag
    20761 catgtcaccg gtgtctaaac caacatccat ttgcataatg gtcacaccag tttctgcatc
    20821 acccgcccat agtgagcgtt ggattggtgc tgcaccgcgc cagcgtggca gcagtgaacc
    20881 atgaacgttg atacagccaa gacgcggcat ctccagcaca gctttaggca gaattaaacc
    20941 ataggcgacg acgaccataa catcagcctg cagatcggcg accagttgct ggttttcttg
    21001 tggacgcagg gaaacaggtt gaaaaacggg cagacctttg tcctcagcca gaactttaac
    21061 cgggctgggc atcagttttt taccgcgtcc tgccggtcgg tctggctggg tgaacacgcc
    21121 aacgatgtta tgaccagaag acaacagcgc gtcgagatga cgcgctgcaa agtcaggtgt
    21181 acccgcaaaa ataatacgta gtgattctga cacgttaatt cttatcctta agcccgggct
    21241 ttcagacgat ccagtttttc aactttctga cgaatacgtt gttgtttcag cggtgacaga
    21301 taatccataa acagtttgcc gaccaggtga tccatctcat gctgaataca gatggctaac
    21361 agaccgtctg cttccagttc aaatggttta ccgtcgcggt ccagggcgcg aattttaact
    21421 ttctctgcgc gtggcactaa agcacgttgt tcagggatcg acaggcaacc ttcttcaatg
    21481 cctgtttcgc cgcttttttc taaaagctcc ggattgatta acaccagccg ttcgtcacgg
    21541 ttttccgaaa catcaattac aatgatacgt tgatggatat caacctgggt tgccgccagg
    21601 ccaatacctt cttctgcgta catcgtctcg aacatatcat cgacgatacg ctgaatttct
    21661 gcattcactt cttctaccgg tttagcaact ttgcgaagcc gctcgtccgg aatatgtaac
    21721 acttgcaaaa ctgacataaa tctccagaga tgtgttcagg agttagaaag attatttctt
    21781 ctattctaga caaatccccc tctgattgac agcatcactg accaatcgca aagattgcta
    21841 aggctgctta tggcagggag ataaggatgg tcgatacaga aatttggctg cgtttaatga
    21901 gcatcagcag cttgtatggc gatgatatgg tccgtatagc tcactggctg gcaaaacagt
    21961 cgcatattga tgcggttgta ttgcagcaaa cagggcttac attgcggcag gcacaacgct
    22021 ttctttcatt tccgcgaaag agtatcgaaa gctcactttg ttggttggag caacccaacc
    22081 atcatttaat ccctgcggac agcgaatttt atcctcctca acttctggcg acgacagatt
    22141 accccggcgc actgtttgtt gaaggagaac tgcacgcgtt gcattcattt cagcttgccg
    22201 tagtggggag tcgggcgcat tcatggtatg gcgagcgatg gggacgatta ttttgcgaaa
    22261 ctctggcgac gcgtggagtg acaattacga gtggactggc gcgtggaatc gatggtgtgg
    22321 cgcataaagc ggccttacag gtaaatggcg ttagcattgc tgtattgggg aatggactta
    22381 ataccattca tccccgccgc catgctccac tggctgccag tctacttgag caaggtggtg
    22441 ctctcgtctc ggaatttccc ctcgatgttc caccccttgc ttacaatttc ccacgaagaa
    22501 atcgcattat cagtggtcta agtaagggtg tactggtggt ggaagcggct ttgcgcagtg
    22561 gttcgctggt gacagcacgt tgtgcgcttg agcaggggcg tgaagttttt gctttgccag
    22621 gtccaatagg gaatccggga agcgaagggc ctcactggtt aataaaacaa ggtgcgattc
    22681 ttgtgacgga accggaagaa attctggaaa acttgcaatt tggattgcac tggttgccag
    22741 acgcccctga aaattcattt tattcaccag atcaggaaga cgtggcattg ccatttcctg
    22801 agctcctggc taacgtagga gatgaggtaa cacctgttga cgtcgtcgct gaacgtgccg
    22861 gccaacctgt gccagaggta gttactcaac tactcgaact ggagttagca ggatggatcg
    22921 cagctgtacc cggcggctat gtccgattga ggagggcatg ccatgttcga cgtactaatg
    22981 tatttgtttg aaacctatat tcacacagaa gctgagttgc gtgtggatca agacaaactt
    23041 gaacaggatc ttaccgacgc aggatttgat cgagaagata tctacaatgc cctgctttgg
    23101 ctggaaaagc ttgcggatta tcaggaagga ctggcagaac cgatgcaact ggcctctgat
    23161 ccactctcca tgcgtattta tacccctgaa gagtgtgaaa gactggatgc cagctgtcgt
    23221 ggttttttgc ttttccttga gcaaattcag gtgcttagcc ttgaaacccg tgaaatggtg
    23281 atagagcgag tgctcgcgct ggataccgca gagttcgacc tggaagacct gaaatgggta
    23341 atcctgatgg tgttgttcaa tattccgggt tgcgaaaatg cgtaccagca aatggaagaa
    23401 ttactctttg aagtgaatga aggtatgctg cattaatcat ttctttaatt cagcataagt
    23461 tgttatggcg aaatcagcac tgttcacggt gcgtaataat gagtcctgcc caaagtgcgg
    23521 ggctgaacta gttattcgat ccgggaaaca cggtccgttt cttggatgct cacagtatcc
    23581 ggcatgtggc tacgtccgtc ctctgaaatc ttcagcggat ggacatattg tcaaagttct
    23641 ggaggggcag gtttgccctg catgtggcgc aaatctggta ttacgccagg gacgctttgg
    23701 tatgtttatt ggttgcagta actaccctga atgcgaacat accgaactta tcgataaacc
    23761 ggacgaaaca gcaattacat gcccccaatg ccggacgggc catctggttc agcgccgctc
    23821 ccgttatggc aaaacatttc actcctgtga tcgctacccg gagtgtcaat ttgccattaa
    23881 cttcaaaccc atagctggag aatgccctga gtgccattat ccgctactca tcgaaaagaa
    23941 aaccgcgcag ggtgtaaaac acttttgtgc cagtaaacaa tgtggaaagc cgatttcggc
    24001 ggaataataa cgtgaataat aacctgcaag gagacgctat cgcagctgcg atagatgtcc
    24061 tcaatgaaga acgtgtcatc gcctatccaa cggaagccgt tttcggtgtc gggtgcgatc
    24121 ctgatagcga aacagcagtg atgagactgt tggagttaaa acggcgtccg gttgataagg
    24181 ggctgatttt aatcgcggca aattacgagc agcttaaacc ctatattgat gacaccatgc
    24241 tgactgacgc gcagcgtgaa accatttttt cccgctggcc aggtcctgta acctttgtct
    24301 ttcccgcgcc tgcgacaaca ccgcgctggt tgacgggccg ctttgattcg cttgctgtac
    24361 gagtcaccga ccatccgttg gtggttgctt tgtgccaggc ttatggtaaa ccgctggttt
    24421 ctaccagtgc caacttgagt ggattgccac cttgtcgaac agtagacgaa gttcgcgcac
    24481 aatttggcgc tgcgttcccg gttgtgcctg gtgaaacggg ggggcgttta aatccttcag
    24541 aaatccgcga tgccctgacg ggtgaactgt ttcgacaggg gtaacataat ggaaacctat
    24601 gctgtttttg gtaatccgat agcccacagc aaatcgccat tcattcatca gcaatttgct
    24661 cagcaactga atattgaaca tccctatggg cgtgtgttga cacccatcaa tgatttcatc
    24721 aacacactga acactttctt tagtgctggt ggtaaaggtg cgaatgtgac ggtgcctttt
    24781 aaagaagagg cttttgccag agcggatgag cttactgaac gggcagcgtt ggctggtgct
    24841 gttaataccc tcaagcggtt agaagatgga cgcttgctgg gtgacaatac cgatggtata
    24901 ggtttgttaa gcgatctgga acgtctgtct tttatccgtc ctggtttacg tattttgctc
    24961 atcggcgctg gtggagcatc tcgcggcgta ctactgccac tcctttccct ggactgtgcg
    25021 gtgacaatca ctaatcggac ggtatcccgc gcggaagagt tggctaaatt gtttgcgcac
    25081 actggcagta ttcacgcgtt gggtatgcac gaactggaag gtcatgagtt tgatctcatt
    25141 attaatgcaa catccagtgg catcagtggt gatattccgg cgatcccgtc atcgctcatt
    25201 catccaggca tttattgcta tgacatgttc tatcagaaag gaaaaactcc ttttctggca
    25261 tggtgtgagc agcgaggctc aaagcgtact gctgatggtt taggaatgct ggtggcacaa
    25321 gcggctcatg ccttccttct ttggcatggc gttctgcctg atgtagaacc ggtcatcaaa
    25381 ctattgcaac aggagttgtc agcgtgaatc aggccatcca gtttccggat agggaagagt
    25441 gggacgagaa taaaaaatgt gtatgttttc ccgctctcgt gaatggtatg caactgacat
    25501 gtgcgatctc tggcgagagt ctggcgtatc gctttactgg agatacacca gaacagtggt
    25561 tagagagttt tcgtcagcat cgctgggacc tggaagaaga agcggaaaac ttaattcagg
    25621 aacaaagtga agatgatcaa ggttgggtgt ggttaccctg atccatatat tcgtccttcc
    25681 atttcacgta gttatttgcg gaatagcgta acccagcctt ctcttcatca cttaacgggc
    25741 ggatctgttt gacggggcta ccgagataca gatatccgct ctccagccgt ttattttgtg
    25801 ggaccaggct acctgcacca atcatcacat catcttctac tattgcgcca tcaagtaaaa
    25861 ttgagcccat cccaaccaaa actcgattgc caatggtgca gccgtggagc atcaccttgt
    25921 gaccaatagt gacatcttcg ccaatggtta atgggttgcc agctgggttg tacgaggatt
    25981 tatgagtgac gtgcaacata ctgccatcct ggatattggt gcgtgctccg atctgtacat
    26041 aatgtacatc tccacgaatc acaacgagcg gccagatccc cacatcatca gccagacgaa
    26101 cgtcaccaat cacgacgctg ctatcgtcga tcattacgcg ctgaccgatt tgtggaaaaa
    26161 gatcgcggta tgggcgtaaa acctcagaca tactcacctc aacaataaat gatttactaa
    26221 tgactttggg tacattattg gccttgtgca agtcttttag tatgcaaaaa agcaccgttt
    26281 tgtgtgcgaa tgcagcaaaa agggtgaaaa aacaacaaac agaaaaaaag atcaaaaaag
    26341 tacttgtgca aaaaattggg atccctataa tgcgcctccg ttgagacgac aacgtgaaac
    26401 acttcacaag atagtcgtaa caacaaagag aaaaatcctg aaattcaggg ttgactctga
    26461 aagaggaaag cgtaatatac gccacctcgc gacagtgagc tgaaaaccgc gtcgcaactg
    26521 ctctttaaca atttatcaga caatctgtgt gggcactcga agatacggat tcttgacgtc
    26581 gcaagacgaa aaatgaatac caagtctca
//
LOCUS       DAPOXO010000072        26307 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPOXO010000072 DAPOXO010000000
VERSION     DAPOXO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26307
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.072"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..971)
                     /gene="pilV"
                     /locus_tag="ROH59_003575"
     CDS             complement(<1..971)
                     /gene="pilV"
                     /locus_tag="ROH59_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="HDX4806014.1"
                     /translation="MKKFRHDDDKGFILLEILAGLIVIGIATPLIYSEIENWLNEQLY
                     QSAASHADAYNTAARNYIADNNATLHNGSLPANFTADDLIRKGYLKQGFNRSPFGQSY
                     ITGIRRNQTTGRLEALTCSTGGQNIKEDGLRSVAGQLPGLGGYIGKNGTATGAFGAWT
                     DKPGDYGLTCSAGHIAVVMTGDDLQESDRLYRFQVPGRPELNQMHTAINMGGNDINNA
                     GNLNGQKATVKGDITSEDGWLITRNNKGWMNTTHGGGFTMTDSQWIRAVNNKGITTDG
                     EIKGGKVSGGTIRSDGRLSTGEYLQLDKTAVANTKCSPDGLVGRDSKG"
     gene            complement(968..1618)
                     /locus_tag="ROH59_003576"
     CDS             complement(968..1618)
                     /locus_tag="ROH59_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDX4806015.1"
                     /translation="MSALLSMTIIIIILAVILYLAYSTAALYLSAVHDTRPPRPVVYV
                     CCLLAIVSVSLNGAYGVEATGLLFLSILTGLLTVMTLTDIAVCRLPRIFTLSLIVLGA
                     AFRYSLEELTYSLLNASLWFGMTYLLRQFFITAKGTEALGLGDVFLIAGIAMWTQPQH
                     TPLLITAAASGAFLFILLFCRRRRQQALPFAPFLCASLYALTLLPDSVFRTSEIFT"
     gene            complement(1635..2117)
                     /locus_tag="ROH59_003577"
     CDS             complement(1635..2117)
                     /locus_tag="ROH59_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDX4806016.1"
                     /translation="MKWLFFSAVICPLFFALPAKAAATNTSLNSCFIQAGKRYLIAPE
                     LLKTIAQQESSLVATAINHNKNKSGKIISTDYGIMQINSVHIPELKKLGVIKDKNDLL
                     NNPCLNIQTGAWILARHFQRCGVNWECLGSYNAGFSKNNTARRMIYARKIHNRYFRQY
                     "
     gene            complement(2165..2701)
                     /locus_tag="ROH59_003578"
     CDS             complement(2165..2701)
                     /locus_tag="ROH59_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009447271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDX4806017.1"
                     /translation="MNFRSCLYSYFALKKEKEEDKGLTLLEIAGALIIIGIVVALAMS
                     QMSSTMSSSDNQRELKNLQTIATKMKQYKFQGRYTGTDYIKTLTESGSLPADMIAGSN
                     KAKNAWGGDVTIAATSNKYGYTITSKAVPKENCVELINSLRSSSMFTKIKGQTPASVD
                     PVTVCSAATNDITLETSS"
     gene            complement(2753..3853)
                     /locus_tag="ROH59_003579"
     CDS             complement(2753..3853)
                     /locus_tag="ROH59_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDX4806018.1"
                     /translation="MRFLEKLNNTDIELTALTVWIARKTFALNRVEFYEALGGMIRDG
                     TPSLRALEFLCEIETDFGEKKGTSGMYFLAKECIDSIKASGMLSGTLLTWVPPEEATL
                     IRNGEERGNIADALFQVARTVKARREMTSSLIAVCLYPLLLLSLCVVNMYNAHTRIIP
                     IVSAFASEDKWSFQMKLLAGMSEFFIGYGFWLCGTIFALTLLIRFSFSRYTGPGRRML
                     DKAPPWSLYQTLHGVNYLFSISSMLQINIPLSQALLRMEKGAEKNKWLKERIQAIRKH
                     VLSGQNLATAMRNSGYDFPSRICINKLLLNSEREDSVATMALYADQWLEEAKKRVKRI
                     GLIITGISGGFVFFFILNMISAIYSISDMLKQ"
     gene            complement(3855..5363)
                     /gene="tadA"
                     /locus_tag="ROH59_003580"
     CDS             complement(3855..5363)
                     /gene="tadA"
                     /locus_tag="ROH59_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDX4806019.1"
                     /translation="MLDPADLPPDDILDYVAIDTDNTGQLRVRVVKGKKHLRAVQEYL
                     TRLRARHQGRVGDFEFTTLDVIARLRQDTTTAGDESVINPVQQKMLGYIRHSASLGAS
                     DLHMTPGRDNTDFTYVEARVHGELEVLDILRKEEGLELLGATYSGMTDVIKGTQFDPG
                     VPQDARLSEQYLKLAGLFGARYSHYPCVGGLYAVLRLIKDDSQQIPTFSMLGYHPDQE
                     RTLRRILQRPEGIITLSGPTGSGKSTTLRTASAAYLEQYGFNNTGGILLPRRRLFTIE
                     SPPEGRIPGAIQTAVMDTAQGWVDSIKSALRLDPDGILNGEIRDHDSAITAIKAAMTG
                     HLMLTTIHANDPINILERLEMEGVQARMIADPQLFIGLLSQRLVQLICPHCRRPWHEV
                     ATERTDDERRLVESVCNPDQVYLRNHEGCPHCWRGVTGRTVIAEVISPDARFFQLYRE
                     KGRIEARTYWHRELGGMTRNQHLLGKINSGQVDPLAAHYISPIDEDSYTLLH"
     gene            5554..5805
                     /locus_tag="ROH59_003581"
     CDS             5554..5805
                     /locus_tag="ROH59_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDX4806020.1"
                     /translation="MSYQILTTTAASITELKKNPMGTVAEGEGGAVAILNRNEPAFYC
                     VPPELYAYYRELAEDAELNAIADERMKNPDIVKVSLDDL"
     gene            5795..6076
                     /locus_tag="ROH59_003582"
     CDS             5795..6076
                     /locus_tag="ROH59_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDX4806021.1"
                     /translation="MTYELEFERRALKEWHKLGHTVREQFKKKLSERLKNPRVPAARL
                     HGHTDRYKIKLRASGYRLVYQVIDEKIVLLVIAVGKRESSEVYQMADIR"
     gene            complement(6386..6838)
                     /gene="pilP"
                     /locus_tag="ROH59_003583"
     CDS             complement(6386..6838)
                     /gene="pilP"
                     /locus_tag="ROH59_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilP"
                     /protein_id="HDX4806022.1"
                     /translation="MHAKTKALLVSVLLLPTTVMATDGNAPPQNRQQLQIEQIQDETA
                     LYEAMLAREKIRHELRTLELGVPAEARGQPESTSAVTTNTQALPSPRLTEIFGVQPHL
                     SARIELPGGNITDVKAGQNLPGTPYLVEKITPDSVVLEQSGIRKTLRP"
     gene            complement(6828..8123)
                     /gene="pilO2"
                     /locus_tag="ROH59_003584"
     CDS             complement(6828..8123)
                     /gene="pilO2"
                     /locus_tag="ROH59_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4b pilus protein PilO2"
                     /protein_id="HDX4806023.1"
                     /translation="MTDISPTERQMFPLTAGRNVFLAGLEWKTLPSQYRHVRDFARAQ
                     KADLFLACQYLSNDDADTHTMVATASRRILPGKTRQCFSLALLILPLLEQGGYAITEL
                     TLPGETPRYSFVSAVDGVLVSDLVGSGEEVREARDTFLSINTEPVQSWTRYEPVAFSA
                     GDQNQPLPLSTLTGSGKHPAAARLNPVSRGAQFITVSLIITLLGAAWYGWQYYERWQT
                     EKAAQAAAARQVTEERISPPWPGLPETDAFIRGCADIWASLPLSAAGWRYSLAECSTE
                     GDNGNLRASYTNTAGTTVTDFIRRISDMTGTRPFIVMPEGKNGGIGLPVTFRLSEHPV
                     EVDALPETSVLQEQLTTLAQSMQLTLDWQEVSNSVTDENGNIIQPPWKEYDLQIQTAL
                     PVHQLAERLKAPSVRFISVTRQLENGRFHYQFTGKYYAR"
     gene            complement(8144..9763)
                     /locus_tag="ROH59_003585"
     CDS             complement(8144..9763)
                     /locus_tag="ROH59_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN family type IVB pilus formation outer
                     membrane protein"
                     /protein_id="HDX4806024.1"
                     /translation="MNKKILVIMISAALLQGCASFRQLESTRKEAVAEQQRAREMMSD
                     LRTRMPVVKESSRQWINPRPVMDKNTGKTVPGCPIVIHTRQSITLQQVVQRITESCHI
                     PVRITPDVLTYLNTSTTGSTQQIQGALPPPDASGMVPLAAIGASDTPQSRLPGNASSL
                     SELNASGLTSLLNAVSSRLGISWRYDGSHITFYYLDTRTFPITYMDSQVAYNATVVSG
                     TMSSNGSSGGDASDAISGDASNTQTTTVDMKSALYQDVKNAVTSMLTPGVGRMFMSTG
                     FITVTDNPQVLETVRAFIEKRNEEMKRQVVLNVEILSIRKTRNEQAGIDWNAVFSDRT
                     LGLSLGSTFTGAASDAITGGVSIVDGKLTGSKAFLKALSSQGDVSVVTQNSAVTKNLT
                     PVPMQIANQQSYIESVTTDTTANVGSSTSLNAATITTGFNMTLLPFILPDSQTLQLLY
                     SMSLSDKPVIENYESGGSKAQLPNVDLKTINQTVDLKSGQTVIISGFQQSGRRSGKQG
                     VGTPGFFGLGGGINSENDDTILVVLITPNII"
     gene            complement(9794..10231)
                     /gene="pilM"
                     /locus_tag="ROH59_003586"
     CDS             complement(9794..10231)
                     /gene="pilM"
                     /locus_tag="ROH59_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="HDX4806025.1"
                     /translation="MGWFIVFIMVITTTGNFWFTSQLSRSEHRYQAAENTQQAATFIR
                     YMNAINDYLHQHPERRTAGGRLTSAQLGLPGTDTVSHIISQQRVFVWATETPGLMAAL
                     REQSNDSALLGRVENGRLLDTAGRALSVTLPSVIPDHVILWMN"
     gene            complement(10236..11303)
                     /locus_tag="ROH59_003587"
     CDS             complement(10236..11303)
                     /locus_tag="ROH59_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpQ domain-containing protein"
                     /protein_id="HDX4806026.1"
                     /translation="MQKKSLTLLLPSLLSGCTAFNATPVPDTTPPALVFVDGQIRESA
                     AIIAHTQKRLLPPPVTRPVTPPRPTMATPTATVSSQSTALPPRPALQTTPMSALIMTG
                     KPGPSSVVYLREARQRTISDWIRQLLPTGWQFRQQNAATPALNKRLPSWSVNDQWHRA
                     LNALLAGQQLYGHMDWNRKILTVTTTATPPVDLTAPQGSQKAADTPRNPFRGSTATPA
                     GPTQVTPAVSASRPQTTTGTSGTPESRTTTPAPVATKPPAPSPQKVTPPRQWKMEKGT
                     TLKDGLARWTSSEKCPHGTWTLRWETPVNYSIDAPLVFTGSFRQALEQLFALYTPAEK
                     PLYARTSTAQCLLRVTDRPQE"
     gene            11423..11851
                     /locus_tag="ROH59_003588"
     CDS             11423..11851
                     /locus_tag="ROH59_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806027.1"
                     /translation="MKNKIFWLRKYKENNSLLQMIASRKQVELLRNIMTDSLLFCSVG
                     FVFLNMCDSKYTLISGEGGLGADCADYLLFFVYAIALLMIILWMTVSVLYSIAEYTSQ
                     EKQGKSKVRSYLWFFIWFFVFNCAVYSSLKTIDIKYLFSQ"
     gene            complement(11841..12728)
                     /locus_tag="ROH59_003589"
     CDS             complement(11841..12728)
                     /locus_tag="ROH59_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806028.1"
                     /translation="MSAPSFIFAILPVILTMCIITSLFWIFIYTRGKWTFSSGITVSR
                     YLQQYRWFHFGNISLLILSVILTARVYDTEYPLQVYICIYIPPVMILTSLLTILTIKE
                     ATRTYKTYKSNRLTPVFIIAYVGLGYLFCFTTGIYELSSTRFNPVVSEMLMSFLSRLS
                     IMLPVTLAEIAVIYLLLLALHFPDGVSARGLSVTRYLRHNDWFYYINTGNAVLALILS
                     TWIYHSSISLTAALFTGALSIFFNTTIPASLSVIEHTPSDTDSKKWDTLKTSPATVLY
                     CSGIGYVIGFIVNPSTAIG"
     gene            complement(13136..13483)
                     /locus_tag="ROH59_003590"
     CDS             complement(13136..13483)
                     /locus_tag="ROH59_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806029.1"
                     /translation="MRTITTREQLLINGRVHERIATHIVTGAHGYETLCTNGYNVRYN
                     TAQQLVESCEKIAEGKLPVTCPVCFAVWQDVHKFTHVDFDTASGKSDFFDTGHMEIIS
                     AYISPCYLTEIFP"
     gene            complement(13600..13917)
                     /locus_tag="ROH59_003591"
     CDS             complement(13600..13917)
                     /locus_tag="ROH59_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="HDX4806030.1"
                     /translation="MPEFFRHLFHKECPHGIFWFKRGLKMSAEKFRVVIYTNTCEKKV
                     SYIPATEDINIAIMPFQTADNGLIIVCQNSRIIRRKERIPGSSCEWKDVTLAPKSRDR
                     VQL"
     gene            complement(13923..15617)
                     /locus_tag="ROH59_003592"
     CDS             complement(13923..15617)
                     /locus_tag="ROH59_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000482663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDX4806031.1"
                     /translation="MFNLPGWLFTVIALVLTLFVIGLIFARLYRRASAEQAFVRTGLG
                     GQKVVMSGGAIVMPIFHETIPVNMNTLKLEVSRAAAESLITRDRMRVDVAVAFFLRVK
                     PSAEGISTAAQTLGQRTLTPEDLRSLVEDKFVDALRATAARMSMQDLQDARENFVQGV
                     QNTVAEDLSKNGLELESVSLTSFNQTAREHFNPDNAFDAEGLTLLTQETERRRRERNE
                     VEQDVEVAIREKNRDALSRRLEIEQQEAFMTLEQQQRVKTRTAEQSASIAAIEAERRR
                     EAESARILAERKIEEAEIERQQIVRTRQVEAEREVAIREIEQQQATEIASQARAIAVA
                     AKSEEQSQAEARASKALAEAVQAQQDVETTRQTAEADRTKQVALIAAAQEAETKAVEL
                     TVRAQAEKEAAELQAAAIIELAEATRQKGLAEAEAQRALNDAINVLSDEQTSLRFRLA
                     LLDALPAVIEKSTEPMKSIDGIKIIQVDGLNGGVPSGKTATTGISGGNLAEQAVTAAL
                     AYRTQAPLIDSLLKEVGLSGEGLTALTRPLVMPAPEKVPDVSEPVTAPDTPEPQQV"
     gene            complement(15644..16264)
                     /locus_tag="ROH59_003593"
     CDS             complement(15644..16264)
                     /locus_tag="ROH59_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HDX4806032.1"
                     /translation="MTLTLLTAYNAPYLAALTFVLLTGIAELIALLCGHSLSSAMDTP
                     DLPEGLTGEALDWLNIGRIPLLIVLCMLAGFFGISGILLQGLIIHLLQAPAPNILLAP
                     LCLLLTCPLVHRTGRLIAPWLPRDETTALTEEAFIGCMATITGYHAVAGSPCEGRFTD
                     RFGQVHYLLLEPEAGKEFRRGDKVIIVCRLSGSRWLGELNPWPDVL"
     gene            complement(16531..17193)
                     /locus_tag="ROH59_003594"
     CDS             complement(16531..17193)
                     /locus_tag="ROH59_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="traC"
                     /protein_id="HDX4806033.1"
                     /translation="MTIQSPENPVIQLLENMLEALSTSPDSINNERRRRRFLLNWLDS
                     ARQMSEFRGMPEEFTALRKLLATNTDIPVENTLKSLLESGHNAALYDLYRFRAALATC
                     RSLGWQIGTCAWNDQLLSETLSRAQTGKRHILQLNSTGDTFSTTGRMIRPVAFSLIHP
                     ATINTSEVEEIFRDEGFMLAHGRECSLNGSGRNMLSRILHVGHSGLAEEEWGMDNSLL
                     LH"
     gene            complement(17333..17974)
                     /locus_tag="ROH59_003595"
     CDS             complement(17333..17974)
                     /locus_tag="ROH59_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusG"
                     /protein_id="HDX4806034.1"
                     /translation="MCLSELQARLNVGQPLFPTHALCIRRSQQHRSPPAGIDFRGAFR
                     ILNISELHQRNWYLAQYIAAGKNREHLFSWLSEQHVLPWTPLILKKVRRTDKVCGYRR
                     HIHAVFPGYFFLKADPESHSFTHLRRHSAFLDFVKMAGEIKTVREDIVQSLMKVYPDP
                     ALNPAAREELDAASTLWLTKARYQYLLRLDAQPLPESRIALLLHLVSDDGALT"
     gene            18676..19548
                     /gene="repA"
                     /locus_tag="ROH59_003596"
     CDS             18676..19548
                     /gene="repA"
                     /locus_tag="ROH59_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HDX4806035.1"
                     /translation="MAALNQTSFTESTYRQVKNPNPVFTPREDAGTLKFCEKLMEKAV
                     GFTSRFDFAAHVAYARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTL
                     AIECGLATESEAGKLSITRATRALKFLAELGLITYQTEYDPTIGCNIPTDITFTPALF
                     ASLDISEEAVASARRSRVEWENRLRKKQGLDALGMDELIARAWRFVRERFRSYQAELK
                     SHGMKRARARRDAGRTRQDIVTLVKRQLTREIAEGRFRGSLEAVKREIDRRVKERMIM
                     SRNNNYTRLATASP"
     gene            20508..20759
                     /locus_tag="ROH59_003597"
     CDS             20508..20759
                     /locus_tag="ROH59_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001595120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDX4806036.1"
                     /translation="MPNIILSDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYC
                     VPAELYERMLDALDDQELVKLVTERSNQPLHDVDLDSYL"
     gene            20756..21043
                     /locus_tag="ROH59_003598"
     CDS             20756..21043
                     /locus_tag="ROH59_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDX4806037.1"
                     /translation="MTYTVKFRDDALKEWLKLDKSIQQQFAKKLKKCSENPHIPSAKL
                     RGLKDCYKIKLRASGFRLVYQVIDDMLIIAVVAVGKREHSNVYNLASERMR"
     gene            21147..21737
                     /locus_tag="ROH59_003599"
     CDS             21147..21737
                     /locus_tag="ROH59_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HDX4806038.1"
                     /translation="MMKNPLAYFHIATFLLSGKSRNLSEYWKAEVIMRDKFVLHRLIR
                     NGLQRQRGFLMWWRLANEMFISGNKKQRKCAIKIKNALMERYGCDIGLGARIGKGLML
                     PHHAGIVIHGNVDIGENVIIRQNTTIGEKVSDSRENYIVIGDNVDIGAHTCIIGLNVK
                     IGSNVKIGAMSFIMEDVPDNCTYVTRKESRVIICEQ"
     gene            21840..22493
                     /locus_tag="ROH59_003600"
     CDS             21840..22493
                     /locus_tag="ROH59_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806039.1"
                     /translation="MGSVTKKPSPVVIIKKKRRILSHQDDAVQAVPDDIKPAPVMEFK
                     TDSLPPEIPATVAGSPEQQKKTGRKKKKKKNNRWNHEFIRHSLDCVKKTFPQLRAEEG
                     GYHAFKIGISKDVMAFISASPECGLTVKEWSCAVRMITGGYKYLQRISVSGTPRYGLD
                     GKVHGTVTEEEALYAQAKLEKHTQRYNARMKETEDARCNQSSTNCHTGQQFEGRLHS"
     gene            22561..22875
                     /locus_tag="ROH59_003601"
     CDS             22561..22875
                     /locus_tag="ROH59_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806040.1"
                     /translation="MITVIISEADGWREWKHRARTKDAQTAIIRAMNKHFPRSYNFIP
                     DDIDNAPVLFAAVTRTPNVKITGHIWKPMWNRGICWNVKGPPVIITLIQGAAWNSENK
                     PR"
     gene            complement(23122..23262)
                     /locus_tag="ROH59_003602"
     CDS             complement(23122..23262)
                     /locus_tag="ROH59_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="HDX4806041.1"
                     /translation="MKKITWIILLLLAAIILAACQANYIRDVQGGTVSPSSSAELTGL
                     GG"
     gene            complement(23360..23611)
                     /locus_tag="ROH59_003603"
     CDS             complement(23360..23611)
                     /locus_tag="ROH59_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012644888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E5 immunity protein"
                     /protein_id="HDX4806042.1"
                     /translation="MKLSPKAAIEVCNEAAKKGLWILGIDGGHWLNPGFRIDSSASWT
                     YDMPEEYKSKIPENNRLAIENIKDDIENGYTAFIITLKM"
     gene            complement(23679..23900)
                     /locus_tag="ROH59_003604"
                     /pseudo
     CDS             complement(23679..23900)
                     /locus_tag="ROH59_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012965.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="colicin"
     gene            complement(24316..25182)
                     /locus_tag="ROH59_003605"
     CDS             complement(24316..25182)
                     /locus_tag="ROH59_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX4806043.1"
                     /translation="MIKGVLFAFLAAFSWGAAIVMSKKGLENMDAGGLFFWQVGSAAM
                     LSWFVLAISRKKLPVTKKSILAYSTGIFEPFLAYTFTLYGLKFISAGITAVIFSLESV
                     FILILSVILFFVKINSPLHFILLLTGAMAGSIMVALPDINDRIDNITGYILIVAGVLS
                     ASFYVVISSRLIVNFEPVTLLTGQLTFSFILACFFIVLTGTSLQLPVESVFLVFLSGI
                     LQYFLAFCFYLYSLRWIPVHIAGAMLYFIPLVALLLSWFFLQEDISFIQGLGVFITIL
                     CVYILNKKYAIE"
     gene            complement(25175..26242)
                     /locus_tag="ROH59_003606"
     CDS             complement(25175..26242)
                     /locus_tag="ROH59_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806044.1"
                     /translation="MNKPLHQHINNLPQLPSDFSFGKDIDSIHKFIFKETDDNIIEKE
                     LRKWASVNQPCVFGKLACKKIKGLDFHLSIIKDPSLYTNDSKLFEFLRRERIIFKERA
                     LKGEVSAHLIYFIHQKIAFAKPSKELVDIQKHICSLHMPEYYPVREDIIYTESIPLQE
                     NENVMVYKAGVNIFYSSAHRTRNHDRRIPGGMLISVNAPGHFMRLAIAKGFYKDQEQA
                     LSDIRNMTIQSIGKGGYSHPEKISTTWHSDNKMNRFGCPIHSTNSDYYSGFYHTDVLI
                     PGELTQDSRIIHNVDSNDPMIFNWNVLFYVSLEKFPVDNPYYGEFLGIPVDEEAKFFN
                     PFPPRAFENKPLYNEEITKYD"
BASE COUNT         6674 a         6109 c         6688 g         6836 t
ORIGIN      
        1 cctttgctgt cgcggcctac aagtccatct ggtgaacact ttgtatttgc tacggctgtt
       61 ttatccagct gtaaatactc acctgtggaa agacgaccgt cagaccggat cgttccaccg
      121 ctgactttgc cccctttgat ttcaccatcg gtggtgatcc ctttgttatt gacggcgcgt
      181 atccactggc tgtcagtcat ggtgaaaccg cctccgtgcg tcgtgttcat ccaccccttg
      241 ttgtttctgg tgataagcca gccgtcttcg ctggttatat cgcctttcac cgtggctttc
      301 tgaccattga ggttaccggc gttattgatg tcatttccgc ccatgttgat ggcggtgtgc
      361 atctggttca gctctggtct ccccgggacc tgaaaacgat acaacctgtc gctttcctgc
      421 agatcatcac ccgtcatgac gacggcaatg tgacctgccg aacaggtgag tccgtaatcc
      481 cccggtttgt ctgtccaggc gccgaatgcg ccggttgctg ttccgttttt accaatataa
      541 ccacccagcc cgggaagctg tcctgccaca ctgcgcagac catcttcttt gatattctgc
      601 ccccctgttg agcaggtcag ggcttcaaga cgtcctgtag tctggttacg gcggataccc
      661 gtgatataac tctgcccaaa cggagaacga ttaaatccct gtttcaggta tcccttgcga
      721 atcaaatcat cggctgtaaa gtttgccgga aggctgccgt tgtgcagagt ggcattgtta
      781 tcggcaatgt aatttctggc tgcggtattg taggcatctg catgagaagc agcactctgg
      841 taaagctgtt cattcagcca gttttctatt tcggaataaa tcagcggcgt ggcgatacca
      901 atcactatca gtcccgccag tatttcaagc agaataaaac ctttgtcgtc atcgtgtctg
      961 aactttttca cgtgaatatc tccgaagtgc ggaaaacgga atcagggagg agggttagtg
     1021 catacagtga tgcgcagaga aacggggcga acggcagtgc ctgctgacgt ctgcgacggc
     1081 agaagaggag gataaacaga aatgccccgg aagctgcggc ggtgattagc agcggcgtgt
     1141 gttgtggctg tgtccacatt gcaattcctg ctatcaggaa tacatcacca aggccgagtg
     1201 cttctgttcc ttttgccgtt atgaaaaact gccgtagcag gtatgtcatg ccgaaccaga
     1261 gtgatgcgtt gaggaggctg tatgtgagct cctccaggct gtacctgaac gctgccccca
     1321 gaacaatcag tgaaagcgtg aatatccggg gaagccgaca gacggcgatg tccgtcagcg
     1381 tcattacagt taataatccc gtcagaatgg aaaggaataa cagccccgtg gcttcaacac
     1441 catatgcgcc gttgaggctg acactcacta tggccagaag gcaacacacg tacaccaccg
     1501 gcctgggcgg ccgggtgtcg tgtactgctg acaggtagag agcggcggtg ctgtatgcaa
     1561 gataaagaat aaccgccagg atgatgatta ttattgtcat gctcagtaat gcgctcaccg
     1621 tcacctcgta tttattaata ttgtctgaaa taccggttgt ggatttttcg ggcatatatc
     1681 atgcgccggg ctgtgttatt tttgctgaaa ccggcgttat agctgcccag acattcccag
     1741 ttaacgccgc agcgttgaaa atggcgggcc agtatccagg ccccggtctg aatattcagg
     1801 cagggattat taagcaggtc atttttgtct ttaatgactc caagcttttt cagctcagga
     1861 atatgcactg aattaatctg cataatcccg taatccgtac tgataatttt cccggatttg
     1921 tttttattgt gatttatcgc agtggcgacc agactgcttt cctgctgtgc aatggttttc
     1981 agaagctcag gggcaataag gtagcgtttc ccggcctgaa taaagcagct attcagtgat
     2041 gtgtttgtgg cggcagcctt agcgggaaga gcgaaaaata acggacaaat cacggcagaa
     2101 aaaaataacc acttcatgcg gatacactcc ggaaaagcgc cccggagggc gctgtgtcag
     2161 gatattaact gctggtttcg agcgtgatat cgtttgtggc ggcagagcat acagttaccg
     2221 gatccacact ggcaggtgtc tggcctttga tttttgtgaa catggatgaa ctgcgcagac
     2281 tgttaatcag ctcaacacag ttttctttcg gtacggcttt actggttatg gtataaccgt
     2341 atttattact tgttgctgca atggtgacat cgcctcccca tgcatttttg gccttgttac
     2401 ttccggcgat catatcagcc ggcagggaac cgctttctgt cagggttttg atataatctg
     2461 tgccggtata tctgccctgg aacttgtact gcttcatttt tgttgcaata gtctgcaggt
     2521 ttttcagttc acgctggtta tcactggatg acattgtgct ggacatctga ctcattgcga
     2581 gagctaccac aataccgatg ataatcagtg caccggcaat ttccagtaat gttaaacctt
     2641 tatcctcctc tttctctttt tttaaagcaa aataagaata aagacatgat ctgaagttca
     2701 tatatcactc ctggtttatg ggatgtttca gaaatattct gtatggtggg gattattgtt
     2761 tcagcatgtc gctgatactg tagatggcag atatcatgtt aagaataaaa aagaagacaa
     2821 aacctcctga tataccggta ataattaatc caattcgttt tacccgtttt tttgcttcct
     2881 ccagccactg atcggcatag agtgccatgg ttgccacact gtcctccctt tcggagttca
     2941 ggagcagttt attgatgcat attctggacg gaaaatcata accggaattt cgcattgctg
     3001 tggccagatt ctgaccggat aatacatgtt ttcgtattgc ctgaattctc tcctttaacc
     3061 atttattctt ttctgcacct ttttccattc ggagcagcgc ctgcgaaaga ggaatattaa
     3121 tctgcagcat ggatgaaata ctgaacagat aattcacccc gtgtaaggtc tgatacagtg
     3181 accagggggg agccttgtcc agcatcctcc ggccggggcc ggtataccgg ctgaatgaaa
     3241 aacggatcag aagcgtcagg gcgaaaatgg tcccacagag ccagaatccg tacccgatga
     3301 aaaattccga catgccggca agcaatttca tctggaatga ccatttatct tctgaagcaa
     3361 acgcactgac gatggggatg atacgggtat gggcgttgta catattcacc acacagagcg
     3421 aaagcagcag aagggggtag aggcagacgg caatgaggct ggatgtcatt tcccgccggg
     3481 ctttaacggt tctggccacc tggaaaaggg cgtcggcaat atttccgcgc tcttccccgt
     3541 ttctgattaa cgtggcttcc tccggtggca cccaggttaa cagggtaccg gataacatgc
     3601 cgctggcttt gatggaatcg atgcattctt ttgccagaaa atacatgccg gatgtgcctt
     3661 tcttttcacc aaaatcggtt tcgatctcgc agagaaattc gagtgcacgc agggacggcg
     3721 ttccgtcacg tatcatgccg cccagggctt cgtagaactc cacccggttc agggcaaagg
     3781 tttttctggc tatccagaca gtcagtgctg tcagctcaat gtcggtgttg ttgagttttt
     3841 ccagaaatct catgtcagtg cagcagcgta tagctgtcct cgtcgatggg agagatgtaa
     3901 tgggccgcca gcggatcaac ctgtccgctg ttgatttttc ccagcagatg ctgatttcgt
     3961 gtcatgccgc ccagctcccg gtgccagtat gttctggcct caatacgccc cttttcccgg
     4021 tacaactgga aaaaacgggc atccggggag atgacttctg cgatcaccgt tcgtcctgtc
     4081 acgccacgcc agcagtgcgg gcagccttca tgatttcgca gatatacctg gtccgggttg
     4141 cagacgcttt ccaccaggcg ccgttcatca tccgtgcgct cggtcgccac ctcatgccag
     4201 gggcgacggc agtgcggaca tatcagctga accagacgct ggctcagcag gccaatgaac
     4261 agttgcgggt cggcaatcat cctggcctgc accccctcca tctcaagacg ttcgaggatg
     4321 ttaatcgggt cgttcgcatg gatggtggtc agcatcagat ggccggtcat ggcggctttt
     4381 attgccgtaa tggcggaatc gtggtcgcgg atttcaccgt tcaggatccc gtcggggtca
     4441 agacgcagtg ccgatttgat ggagtccacc cagccctgcg cggtatccat gacggcggtc
     4501 tgaatggcac cgggaatacg cccttccggc ggggattcga tggtgaacag cctgcgacgg
     4561 ggaagaagaa taccgccggt gttgttgaag ccgtactgtt caaggtacgc cgcagaggcg
     4621 gttctcagcg tggtggattt tcctgagccg gtggggcctg agagcgtgat aatgccttca
     4681 gggcgctgca gaatgcggcg aagagtgcgc tcctggtcag ggtgatagcc cagcatactg
     4741 aaggtcggga tttgctgact gtcatccttg atcagacgga gcacagcata gaggccgccc
     4801 acacaggggt agtgggagta gcgtgcacca aacagaccgg ccagtttcag atactgctct
     4861 gaaagacgtg catcctgagg caccccggga tcaaactgtg tgcctttgat aacatcggtc
     4921 atgccggaat aggtggcccc cagtaattcg aggccttctt ctttccggag gatatcgagc
     4981 acttccagtt cgccgtgaac ccgggcttcc acataggtga agtccgtgtt gtctcgtccc
     5041 ggggtcatat gaaggtctga ggcaccaaga gaggcagaat ggcggatata gccgagcatt
     5101 ttctgctgta ccgggttaat gacgctttca tcaccggcgg ttgtggtgtc ctgtctgagg
     5161 cgggctatca catccagggt ggtgaactca aagtctccca ctcgcccctg atggcgtgcg
     5221 cgcaggcggg tcagatattc ctggacggca cgcagatgtt tttttccctt cacgaccctg
     5281 acccgcaact gaccggtgtt atcggtgtcg atggccacat aatccagaat gtcatccggt
     5341 ggcaggtctg caggatccag cataaagcct ccttacgggc agcggtgccc ggaaaatatg
     5401 ttttctgtca ttaagtgaag gaagtaaaaa taacgttctg gtgaaataac cgtcgacagc
     5461 gaaacgtgtg atggccatct gttcgataaa agcaccttta aaagattttt taaggtgcca
     5521 taatggacaa taagacaaaa ggagaatgac ctcatgagtt accagatttt gaccacgaca
     5581 gcagcaagta ttactgagct gaaaaaaaat cctatgggca cggtagccga aggtgaagga
     5641 ggggccgttg caatcctgaa ccgaaatgag cctgcgttct actgtgtccc tccggaactt
     5701 tatgcctact accgggagct cgccgaagat gctgagctaa acgcaattgc tgatgaaaga
     5761 atgaagaatc cggacattgt gaaggttagt ctggatgact tatgaactgg aatttgagcg
     5821 cagggccctg aaagaatggc ataagctcgg tcatacagtc cgtgagcagt tcaaaaagaa
     5881 actgtcagaa cgcctgaaaa atccaagggt ccctgctgcc aggctacatg gtcatactga
     5941 ccgttataaa atcaagcttc gtgcatctgg ttacaggctc gtctatcagg tgattgatga
     6001 gaaaattgtt ttgctcgtta ttgctgtagg aaaaagggaa agcagtgagg tctaccagat
     6061 ggctgatatt cgctgatatt gtccgcgtaa cgggtgctaa tttctggtgt gatgtcactg
     6121 ccagagcaaa tatactgcgc cgcgagacgc attctgacac ccaacagccg ggcattcagg
     6181 gcgcggagtt gtaccagggg gcgcttttcc ccggcgaagt aattgtcttg cctcgcggac
     6241 aatcgccgtg tagtcaatcc cgtgctctgc agcggctgtt tccaggtccc ggacaatcag
     6301 gctgaggctg gatatcagtt ctctggtgtt catcgttgtc ttttatccct ctggtacgga
     6361 cagccgcctg ttccggcggc cgctttcatg gtcgcagggt ttttctgatg ccggactgct
     6421 ccagtaccac actgtccggc gtgattttct ccaccagata aggggttccg gggagattct
     6481 ggcctgcttt cacatcggtg atgtttcccc ccggaagttc tattcgggcg ctcaggtgag
     6541 gctgtacacc aaatatttct gtcaggcggg gggatggtaa tgcctgtgta tttgttgtga
     6601 ctgcggaagt gctttccggc tgacctctgg cctctgcggg aacccccagc tccagtgtac
     6661 gcagctcatg acggattttt tctcttgcca gcatggcttc atacagggct gtttcgtcct
     6721 gtatctgttc aatctgcagc tgctgtctgt tctgtggagg ggcatttccg tctgtggcca
     6781 tgactgtggt cggcaacagc agaactgaaa ccagaagggc ttttgtttta gcgtgcataa
     6841 tatttacctg taaattgata gtggaaacga ccgttctcca gttgtcgtgt gacagagata
     6901 aaacggacag aaggcgcctt caggcgttca gccagctggt gtaccgggag tgccgtctgt
     6961 atctgaaggt catactcttt ccacgggggc tggatgatgt ttccgttttc atcggtgacg
     7021 ctgttactga cctcctgcca gtccagcgtc agttgcattg actgagcaag cgtggtcagt
     7081 tgttcctgca ggacactggt ttccggcaga gcatcaactt cgacgggatg ttcagacagg
     7141 cggaaggtga ccggcagtcc aatgccgccg ttctttcctt ccggcatcac aataaatggt
     7201 cgggtgcccg tcatatcact gatgcgccgg atgaagtcag tcactgttgt gcccgctgta
     7261 ttggtgtatg acgcgcgcag attgccgttg tcgccttcag tcgagcattc agccagcgaa
     7321 taacgccatc cggcggctga cagtggcagt gacgcccata tgtcagcaca tccccggata
     7381 aacgcgtcgg tttcggggag tccgggccag gggggactga ttcgttcctc tgtgacctgt
     7441 cgggcagcag ctgcctgcgc ggctttttca gtctgccatc gttcataata ctgccagccg
     7501 taccatgcag cgccgagaag ggtgatgatc agcgagacag tgatgaactg cgctccccgg
     7561 gataccggat tcaggcgcgc ggcagccgga tgtttacctg agccggtcag ggtggacagc
     7621 ggcaggggct gattctgatc gcctgctgaa aatgccaccg gttcatagcg tgtccagctc
     7681 tgcaccggtt cggtgttgat ggaaagaaag gtatcccggg cttcccggac ctcttccccg
     7741 cttcccacca ggtcactgac gagaacaccg tcgacagcgg aaacaaagct gtagcgcggt
     7801 gtttctccgg gtaacgtcag ttccgtgatg gcatagccgc cctgttcaag cagtggcagg
     7861 atcagcaggg cgagggagaa gcactgacgg gtttttccgg gcagtatgcg gcgactggcg
     7921 gtggccacca tggtgtgggt gtcggcatcg tcattactga gatactgaca ggccaggaaa
     7981 aggtcagctt tctgtgcccg ggcaaagtcg cggacatgcc ggtactgtga gggcagtgtt
     8041 ttccattcca ggccggccag aaacacattt cgtcctgctg tcagcggaaa catctgccgc
     8101 tctgtcggtg aaatatccgt cacgatcgtc ctccttgtgc aaatcagatg atattgggcg
     8161 tgatcagcac cacgagaatg gtgtcgtcgt tttcactgtt gatcccaccg ccaagaccga
     8221 agaatcccgg cgtgcctacc ccctgttttc cgctgcgacg tcctgactgc tggaagccac
     8281 tgataatgac cgtctgcccg gatttcaggt ccacggtctg attgatggtt ttcagatcca
     8341 cattcggcaa ctgggcttta cttccaccgc tctcataatt ctcaataacc ggtttgtcgg
     8401 agagactcat tgaatagagt aactgcagtg tctgtgagtc cggcagaatg aacggcagaa
     8461 gggtcatgtt aaaaccggtg gtgatggtgg ccgcattcag ggaggtggat gagccgacat
     8521 tggcggtggt atccgttgtc acactctcga tgtaactctg ctgattggcg atctgcatcg
     8581 gcaccggcgt caggtttttg gtgacggcag agttctgggt caccacactg acatccccct
     8641 gggaagacaa tgctttcagg aaggcttttg aaccggtgag tttaccatcc acaatggata
     8701 caccgccggt gatggcatcg ctggcagcac cggtgaatgt gctgccgagg ctcagtccca
     8761 gcgttctgtc gctgaagacc gcgttccagt cgataccggc ctgctcatta cgggttttcc
     8821 ggatactcag aatttccaca ttcagcacca cctggcgctt catttcttca ttgcgttttt
     8881 caatgaacgc ccggaccgtt tccagaacct gtggattgtc cgtgacggtg ataaagcccg
     8941 tggacatgaa catgcgtccg acacccgggg tcagcattga tgtgacggca tttttcacat
     9001 cctgatacag cgcagacttc atatccacgg tggtggtctg ggtattgctg gcatcaccgg
     9061 aaatggcatc tgatgcatct cctcccgatg aaccgtttga ggacatggtg ccgctgacca
     9121 cagtggcgtt ataggccacc tgactgtcca tataggtgat ggggaaggtc cgtgtatcga
     9181 gataatagaa ggtgatatgc gagccgtcat aacgccagga tataccgaga cgggaagaga
     9241 ctgcattcag cagggacgtc aggccggagg cattcagttc agacagtgat gaggcatttc
     9301 ccggcaaacg ggattgtggc gtgtcagatg cgccaatggc ggcaagggga accattccgc
     9361 tcgcatccgg cggtggtaac gcgccctgga tttgttgtgt gctgccggtt gtggatgtat
     9421 tcaggtatgt cagtacatcc ggtgtgatcc gtaccggaat atggcagctt tccgtgatcc
     9481 gctgaaccac ctgctgaaga gtgatgctct gacgggtatg aatgacaatg gggcagccgg
     9541 gaacggtttt gccggtgttt ttatccatga ccggacgggg attgatccat tgtcgtgagg
     9601 actccttaac aaccggcatc cgggttcgca gatcagacat catttcccgt gcccgttgtt
     9661 gttccgcgac ggcttctttt cttgtgctct caagctgtct gaaactggca cagccctgta
     9721 acagggcggc tgaaatcata atgacaagaa tttttttatt catgggagat ccgtgattta
     9781 ttcagattcg tgactaattc atccagagga tgacgtgatc ggggatcacc gacggaagtg
     9841 tgacggaaag cgctctgccg gcggtgtcca gcagtcggcc gttttccacc ctgccgagca
     9901 gggcagagtc attactctgt tccctgagtg cggccatcag ccccggagtt tctgtggccc
     9961 agacaaaaac acgttgctgg ctgatgatat gactgacggt atccgtcccg ggaagcccga
    10021 gctgggcgga tgtcagccga ccgccggctg tccgtcgttc cggatgttga tgcagataat
    10081 cattgatggc gttcatataa cgaatgaacg ttgctgcctg ttgtgtgttt tctgcggcct
    10141 ggtaacggtg ttcgctgcgg gagagctgac tggtgaacca gaaattgcct gtggtcgtga
    10201 tgaccatgat gaacacgatg aaccagccca taaggttatt cctgtggacg atctgtcacc
    10261 cgcagcagac attgtgctgt gctggtccgg gcatacagcg gtttttcagc cggggtatag
    10321 agtgcgaaga gctgttccag cgcctggcgg aaactgccgg tgaaaaccag tggggcatca
    10381 atgctgtagt taacgggcgt ttcccagcgc agcgtccagg taccgtgggg gcatttttcg
    10441 gacgacgtcc agcgggccag tccgtccttc agcgtggtcc ccttttccat tttccactgc
    10501 cgtggcggtg tgaccttctg tggtgatggt gctggcggtt tcgtggccac cggggctggc
    10561 gtggtcgttc tgctctctgg tgttccggat gtcccggtgg tggtctgagg ccgggaagcg
    10621 ctgacggcag gtgtcacctg tgtcgggcct gccggtgttg cggtgctgcc cctgaacgga
    10681 ttacgcggtg tgtccgcggc tttctgtgaa ccctgcggtg ctgtgaggtc aaccggcggt
    10741 gttgcagtgg tcgtgacagt cagtattttc ctgttccagt ccatatgtcc gtaaagctgc
    10801 tggccggcca gcagcgcatt cagtgcccgg tgccactggt cattaacgga ccaggaaggg
    10861 aggcgtttgt tcagtgccgg tgtggcggca ttctgctggc ggaactgcca accggttggc
    10921 agcaactggc gtatccagtc actgatggtg cgctgacgtg cttcacgtaa ataaacgacg
    10981 gatgacggac cgggtttacc ggtcataatc agtgcagaca tcggtgtggt ctgaagggcg
    11041 ggtcggggag gcagtgcggt actctggctg ctgactgtgg ctgtgggcgt agccattgtc
    11101 gggcggggcg gcgtcacagg gcgggtcacc ggtggcggaa gcagacgttt ttgcgtatgg
    11161 gcgataatgg cagcactttc gcgaatttgt ccgtcgacga acaccagagc cggaggcgtg
    11221 gtatccggaa caggcgtggc attaaatgcc gtacagccgc tgagtaatga cggcagaagg
    11281 agtgtcagtg attttttttg catagaataa aatccggtat attacgggtt acgatataag
    11341 acaggtggcg ggtaacaggc cttcagatga atatcatttc atcgggttat tgatgatgaa
    11401 cgttcatgtt cgtgggggga ttatgaaaaa taaaatattc tggctccgga aatataaaga
    11461 gaataatagc ttgcttcaaa tgatagcttc cagaaaacaa gtggagctgt tacgaaatat
    11521 tatgactgac tctttattat tttgctctgt aggttttgtg ttcctgaata tgtgtgattc
    11581 aaaatatacg ttgatttctg gtgagggtgg tttaggtgct gattgtgccg attatttatt
    11641 atttttcgta tatgcgattg cgttgctgat gataatttta tggatgacag tttcagttct
    11701 ttattccatt gcggaatata cgagtcagga aaaacagggg aaaagtaaag tccgtagcta
    11761 cctctggttt tttatctggt tttttgtttt taactgtgcc gtatattctt ctctgaagac
    11821 aatagatata aaatatttat tcagccaata gcagtagagg gattcacgat aaagccaata
    11881 acgtaaccga ttcccgagca ataaaggact gttgccgggg atgtttttag cgtatcccat
    11941 ttctttgaat cggtatcaga tggcgtgtgt tcaatgaccg ataaactggc cggaatggtc
    12001 gtgttaaaaa aaatacttaa cgcgcctgta aataaagcag cggtaagaga aatgctggaa
    12061 tgatatatcc atgtggagag tatcagtgcc agaacagcat ttcctgtatt tatataataa
    12121 aaccagtcgt tatggcgcag ataccgggta acggagagcc ccctggcgga cacgccatcc
    12181 gggaaatgca gcgccagaag cagaagataa ataactgcta tttcagccag tgtgacaggc
    12241 agcataatgg aaagacgtga caggaatgac atcagcattt cactgacaac aggattaaat
    12301 cgtgttgaag ataattcata aatgccggtt gtaaaacaga acagatatcc cagtccgaca
    12361 taagctataa tgaaaaccgg cgtcagtctg tttgatttat atgttttata cgttctcgtt
    12421 gcttctttaa tcgttaaaat tgtcagcagg gaggtgagaa tcataacggg tggtatatat
    12481 atgcagatat atacctgcaa agggtactca gtatcgtata cccgggctgt taatataact
    12541 gacaggatta gtaaggatat attcccgaaa tgaaaccagc gatactgttg aagataccgg
    12601 gaaacagtga tgcctgaaga aaatgtccat ttgcctcgag tataaataaa aatccagaat
    12661 aaagacgtaa tgatacacat tgtcagtata acgggtaata ttgcaaaaat aaatgatggt
    12721 gcgctcatta ttaaatctcc atctgtatgg taatgcttaa atctttacgg ggtgaggtgc
    12781 gatgaagaag gtgacagaaa tgtatcatta tggattcagc gacatataga aaaagctaaa
    12841 cgcgatcatt gatactgaaa aataatatat ccatgagtag aaaaatatga atttcggaga
    12901 tggtttctgc tgtctcctgt ttttcagggg agcctgtggg tcgaatgtta tcagcgtcat
    12961 tacaggatac cctttcataa gaataaaaat atagacgcat aaatgagcgt aaagaggtaa
    13021 cctgtcctgc cagaacagaa tcatcattat gacggcaaga tgaaatgtcg ttacattgat
    13081 ataataaaac cggtcagagt gacgggtgat atagttataa gcagaaagag tatgctcatg
    13141 gaaatatctc tgtcaaataa cagggggata tatatgcaga gataatctcc atgtggccgg
    13201 tatcaaaaaa atcacttttc cccgatgcag tgtcaaagtc aacgtgggtg aacttgtgta
    13261 catcctgcca tacggcgaaa cagacaggac aggtaacagg tagtttacct tcagctattt
    13321 tttcgcagct ttcaaccagt tgctgcgccg tgttgtatct gacgttatag ccatttgtgc
    13381 aaagcgtttc atacccatga gctcctgtaa ctatatgtgt ggcgattctt tcatggactc
    13441 ttccattaat taataattgt tcacgcgttg tgattgttct catgcctgtt tctccgttgg
    13501 tcataacaga aaataatctg cattcctgaa aaatatcgcg gttgtgaaat atttaatttt
    13561 taccctcctt ttatgggggg taaaaagcag gctgtcaggc tataactgaa cgcggtccct
    13621 ggattttggt gctaatgtca catctttcca ttcgcagctg cttccgggta tacgctcttt
    13681 gcgtcgtatt atacgggagt tctggcacac aataattaag ccattgtctg ccgtctgaaa
    13741 tggcattata gcgatgttta tatcttctgt tgcaggaata taactgactt tcttttcaca
    13801 tgtattggtg tatatgacaa ctctgaattt ttcagcggac attttcaatc ctcttttaaa
    13861 ccagaatatc ccgtgagggc attctttgtg aaaaagatgc cggaaaaatt ccggcacggg
    13921 gattaaacct gttgtggttc cggggtatcc ggagcggtta ccggttcgct gacatccgga
    13981 accttttccg gggcaggcat gaccagtggg cgtgtcaggg cggtaagtcc ttcaccggat
    14041 aaccccacct ctttcagcag ggagtcgatg agtggcgcct gtgtacggta agccagagcg
    14101 gcggttactg cctgttcagc gagatttccg ccacttatgc cggttgttgc tgttttaccg
    14161 ctgggaacac cgccattcag gccatccacc tgaatgattt taatgccgtc aatggatttc
    14221 attggttctg tggacttctc tatgacggca ggtaatgcat ccagcagggc aagacggaag
    14281 cggaggctgg tctgctcatc agaaagcacg ttaatggcat cgttcagtgc gcgctgtgct
    14341 tctgcttctg ccagaccttt ctgacgggtg gcctccgcca gttcaataat tgctgctgcc
    14401 tggagttcgg ctgcttcttt ttcagcctgt gcgcgaaccg tcagttcaac cgctttcgtt
    14461 tctgcttcct gagcggcagc aatcagggca acctgtttgg tacggtcggc ctccgctgtc
    14521 tggcgggtgg tttccacatc ctgctgggcc tgtacggctt cagccagtgc tttacttgcc
    14581 cgggcctctg cctgtgactg ctcttccgat tttgctgcca cggcaatggc tctggcctgg
    14641 ctggcgattt cagttgcctg ctgttgctct atttcccgta tggccacttc ccgttcggct
    14701 tcgacctggc gggtacgcac tatctgctgt cgttcgattt cggcttcctc tatcttacgt
    14761 tcagccagaa ttcgcgcgga ttctgcttca cgacgtcgtt cagcttcaat agcagcaata
    14821 ctggcactct gctctgccgt acgggttttt acccgttgtt gttgctccag agtcatgaag
    14881 gcttcctgct gttcaatctc cagacgtcgg gagagtgcat cccggttttt ttccctgatg
    14941 gccacttcaa catcctgctc aacttcgttg cgttcgcgac gacgacgttc agtttcctgg
    15001 gtcagaagcg tcagcccctc tgcgtcaaag gcattgtcag gattaaaatg ttctcgtgcg
    15061 gtctggttga aacttgtcag cgacacactt tcaagctcca gaccgttttt ggataagtct
    15121 tccgcaacgg tgttctgcac accctgaaca aagttctcgc gggcatcctg taaatcctgc
    15181 atgctcattc tggccgccgt ggcccgtagg gcatcaacaa atttatcctc gaccagacta
    15241 cgcagatctt caggtgtgag cgtgcgttgt cccagcgtct gggctgcagt ggatattcct
    15301 tcggctgatg gttttacccg aagaaaaaag gcaacggcaa catcaacacg catgcggtcg
    15361 cgggttatga gactttcagc cgctgcacga ctgacttcca gcttcagggt gttcatgttg
    15421 acgggaattg tttcgtgaaa aatgggcata acaattgcac cgccactcat taccactttt
    15481 tggcctccca gacctgtgcg gacaaaggcc tgctctgccg atgcccggcg gtacaggcgg
    15541 gcaaatatca gcccgataac gaacagggtg aggaccagcg ctataacggt aaacaaccat
    15601 cccggaagat taaacatagt gagaacctct gtatatgtcg ggattaaaga acatccggcc
    15661 agggattcag ttcgcccagc cagcgggaac cggaaagacg gcagacaata atcactttgt
    15721 ctcctcgtct gaattctttc ccggcctccg gctccagcaa caggtaatga acctgcccga
    15781 agcggtctgt gaagcgacct tcacaggggg aacccgccac tgcgtgataa ccggtgatgg
    15841 tggccataca gccgatgaat gcctcctcgg tgagcgccgt tgtttcatca cggggtaacc
    15901 agggggcaat cagtctgccg gtgcggtgta cgagaggaca tgtcagcagc aggcaaagtg
    15961 gtgcaaggag aatgttcggg gcaggagcct gcagcagatg aataataaga ccctgcagga
    16021 gaatgccgga tataccaaaa aaacctgcca gcatacagag gacgatcagc agggggatcc
    16081 gtccgatgtt cagccagtcc agcgcctctc ctgtcagacc ctccggtaaa tcaggtgtat
    16141 ccatagctga agagagggag tgtccgcaga gcagggcgat aagttcagcg ataccagtaa
    16201 gcagaacaaa agtcagggct gccagatagg gtgcgttata cgcggtaagt aacgtcagtg
    16261 tcatttttcc tcctgtggca ggtcagtcaa acaacattat ggcgtgaagc ttccgcttct
    16321 ttaattgtca gaagaagcat atcgtcagtc atcagaagac aaggggatgt ctgcaggagg
    16381 ggatgataac aacagaagcc tcacgccgga atgcgcttta tgacaaccgg agaggacgga
    16441 taatcaaaaa tgggacatcc acatcagcaa accgcgattt gcgaaaaaaa gtcagcggag
    16501 agtggctgcc gttgtggctg tcccggtatt tcagtgtaaa agcagactgt tgtccatgcc
    16561 ccattcctct tccgctaaac ctgaatggcc cacatgaaga atgcgtgaca gcatatttct
    16621 gccgctgccg ttcagactgc attcgcgccc gtgtgcgagc ataaaacctt catcccggaa
    16681 tatctcttca acctcagacg tgttgatggt ggccggatgg attaatgaaa atgccaccgg
    16741 tctgatcatt ctgcccgtgg tggaaaaggt gtccccggtg ctgttcagct gcaggatatg
    16801 acgtttcccg gtctgtgcgc gggaaagtgt ctcactcagt aactggtcat tccatgcgca
    16861 cgtgccaatc tgccatccca gactcctgca cgtggcaagc gctgctcgga agcggtacag
    16921 gtcatacagt gctgcgttgt ggccactttc cagcagtgat ttcagcgtgt tctctaccgg
    16981 tatgtccgta ttggtggcca gcagtttgcg cagggcggtg aactcttcag gcatccccct
    17041 gaactcactc atctgtcggg cggaatcaag ccagttcagc aggaagcgcc ggcgacgtcg
    17101 ttcattgttg atgctgtccg gggaggtgga gagcgcttca agcatattct ccagtaactg
    17161 aatgacaggg ttttccgggg attgaatggt cataacgatg tcctgaaaaa aaatgcccgg
    17221 cagccgctct ccgtacacgc aggtgtcacc ggtgccgggc attggggaaa agatggggaa
    17281 aaaaagcccg gccataaagg ccgggaaagt tgtcaaatga agacagcaat tttcatgtca
    17341 acgctccgtc atcagatacc aggtgcagga gcagggcgat cctcgactcc ggcagaggct
    17401 gggcatcaag ccggaggagg tactggtaac gcgcttttgt cagccagagg gtggaggcag
    17461 catccagctc ctccctggct gccggattga gcgcaggatc cgggtacact ttcatcaaag
    17521 actgaacgat atcctccctg acggttttga tttcaccggc cattttcacg aagtccagaa
    17581 aggcactgtg acggcgaagg tgagtgaagc tgtggctttc ggggtctgct ttcaggaaaa
    17641 agtaaccggg aaacacggcg tgtatatgtc gacggtaacc acagacttta tccgtgcggc
    17701 ggaccttttt cagtatcagg ggtgtccagg gaaggacgtg ttgttcggaa agccaggaaa
    17761 agagatgttc gcgattttta ccggcagcaa tgtactgtgc cagataccag ttgcgttgat
    17821 gtaattcact gatattcaaa atccggaacg ctccgcgaaa atcgatcccc gcaggggggc
    17881 ttcgatgttg ttgtgaacgg cgaatacata aagcatgtgt cggaaacagc ggctgaccca
    17941 cgttcagcct ggcctgcagt tctgacaggc acatgattta cgcactcttg taagccttgt
    18001 ggacggtttc gaggcgggcg aaaaccgaca actcctgcaa acaggattaa tggctggaaa
    18061 atatattaca taaggatgta tctgtggcaa gagtgaagat aagcagtcga atagatcgtt
    18121 atatttgaaa tgacagaata ttattctata tttgatgttg tgtgcgggat attagatcgt
    18181 ttaaaaaaat tcggcgatct cttctactgg aaaagaagaa aaaagcagca taaaagatcg
    18241 tttgcggaat tgttcatttt ttgacacagt tcaaaaaaac gacgcttttt aggtggttaa
    18301 tgagaggcca ggtaaatcag agaaatcgtg tcggcttttc aaagcggtgg aaaaggggta
    18361 tattgcggag cgttatgcag tgacttttgg gatcctcacg atccggaaag tcagaaaacg
    18421 gcaggatgcg ccataaggca ttcaggatgt atggcagaaa cgacggctgt ttgccggggc
    18481 cggaaggctg aaaaaagttt cagaagacca taaaggaaaa cccccataat ctttcatcga
    18541 aacttggcgg aatcactgaa agataatggg ggcctcacag aatacgggat aagtatatat
    18601 gaaaccgtgt cagagattca acccttcgca gtgcattaac gcacggcatt ctgtttccgc
    18661 cataagcgac agcttgtggc ggccctgaac cagacctcat ttactgaaag cacataccgt
    18721 caggtaaaga acccgaatcc ggtcttcaca ccccgtgaag atgccggaac gctgaagttc
    18781 tgcgaaaaac tgatggaaaa ggccgtgggc ttcacctccc gttttgattt tgccgcgcat
    18841 gtggcgtatg cacgttcgcg cggcctgcgc cggcgtatgc cgccggtgct gcgccgaagg
    18901 gcgattgatg cgctgctgca ggggctgtgt ttccactatg acccgctggc caaccgcgtg
    18961 cagtgctcca tcaccacgct ggccattgag tgcggactgg cgacggagtc tgaggccggg
    19021 aaactctcca tcacccgtgc cacccgtgcc ctgaagttcc tggctgagct ggggctgata
    19081 acctaccaga cggaatacga cccgacaatt ggctgtaata tcccgaccga catcacgttc
    19141 acgccggcac tgtttgcctc actcgatatc tcagaagagg cagtggcttc cgcacgccgc
    19201 agccgcgtgg aatgggaaaa caggctgcgc aaaaagcagg ggctggatgc gctgggtatg
    19261 gatgaactga tagcgagggc ctggcgtttt gtgcgcgagc gtttccgcag ttatcaggca
    19321 gagcttaagt cccacggcat gaaacgtgcc cgtgcgcgcc gcgatgcagg caggacccgt
    19381 caggacattg tcaccctggt gaaacggcag ctgacacgtg aaatcgcgga agggcgtttc
    19441 cgcggaagcc tggaggccgt gaagcgcgaa atcgaccgtc gcgtgaagga acgcatgata
    19501 atgtcgcgga acaacaacta cacacggctg gccactgcct caccctgagt ttgacctcat
    19561 ctgaataatc cggcctgcgc cggaggcttc cgcacgtctg aagcccggcg acgcacaaaa
    19621 aagcagcaca gcacacaaaa aacagcctca tcatctgcct tccggctcgc cttgctcccc
    19681 ctgtttttca cgcaaaacac gtctcactga cggggaattc tgtttatcca catttaactg
    19741 caagggactt ctcagtaagg ttacaaccgt tcatgctata aagcgccagc cgcaggcgtt
    19801 acagggtgca atgtttcttt taaaccccag tactgtattt cctttaaact acttaattac
    19861 ttccatttaa aaaaaagacc tattcagtgc ctgtcctgtg gacagacaaa tatgcacctc
    19921 ccacgctaac gcgcgggccc cgaacctcac cgttctgaaa ccacaacaaa aaagacatca
    19981 ggaataaaaa caccacacaa acgcagcacc gtgcccaccc ctcataactg aaaagcgaga
    20041 ccgcccccgc ccgaagggcg ggaacaacat cgcttttaat tatgaatgtt gtaactacac
    20101 agcatcatcg ctgtcagtct tctggctgga tgtactgaat acacgctcgt aagcggccct
    20161 gacggcccgc taacgcggag atacgccccg acttcgggta aaccctcgtc gggaccactc
    20221 cgaccgcgca cataagctct atcgtggctg aaagcgggta tggcttagca gggctgagga
    20281 tgggtaaggt gaaatctatc aatcagtacc ggcttacgcc gggcctcggc ggttttactc
    20341 ctgtgccata tgctacaacg gagtaccgcc ttccatgccg ctcacgcggc atcagaacaa
    20401 taaaaccagc attaaatgta tttgcaaaag tatgagtaat acagacttgt taaccggtcc
    20461 tttcagaggt atctttaaga cttgttaaac agtctcaaag gtacgttatg cctaacatca
    20521 ttctgtctga caccagtgca agtgtcagtg aactgaaaaa aaatcctatg gctacagtca
    20581 gtgccggaga tggttatcct gtcgccattc ttaaccggaa tcagccggca ttctactgtg
    20641 tgcctgcgga actctatgaa aggatgcttg atgcgctgga tgaccaggaa ctggtgaaac
    20701 tggttactga acgcagcaat cagccactgc atgatgtgga cctggacagt tatttatgac
    20761 ttatacagta aaattcaggg atgatgcgct caaagaatgg ctgaaactgg ataaatccat
    20821 tcaacagcag tttgcgaaaa aactaaagaa atgcagcgaa aatcctcata ttccttccgc
    20881 aaaactgcgt ggattaaaag actgctacaa aatcaaactt cgcgcatcgg ggtttcgtct
    20941 ggtctatcag gttattgatg acatgctaat tattgcggtt gtcgcggtag gtaaacgtga
    21001 acatagtaac gtttataatc tcgccagtga gagaatgaga tagttatctt taaagctgac
    21061 tgatattact ttaaaagtat ttctgatagt tatgttattt tattccacaa tacagaatat
    21121 tttctttatt ctttaaggtc gtttttatga tgaaaaatcc attagcttat tttcatattg
    21181 ccaccttttt attgtcaggt aaaagtcgta atctgtcaga atactggaaa gccgaagtca
    21241 tcatgcggga taagtttgtc ttacaccgcc tgataagaaa cgggttgcag agacaacgag
    21301 gctttctgat gtggtggcgc ctggccaatg agatgtttat ctctggaaac aaaaaacaaa
    21361 ggaaatgtgc gataaagata aaaaatgcac ttatggaacg gtatggatgt gatatcggcc
    21421 tgggcgcgcg gattggtaaa ggcctcatgt tacctcatca tgcaggaatc gtcattcatg
    21481 gtaatgttga tatcggtgag aatgtcatta tacggcagaa tacaaccatt ggtgaaaagg
    21541 tttctgacag tagggaaaac tatattgtta ttggcgataa tgtcgatatt ggtgcccata
    21601 catgtattat tgggttaaat gtgaaaatcg gaagtaatgt taaaatcggg gcaatgtctt
    21661 ttattatgga agatgtacct gataactgta cttatgtcac caggaaggaa tccagagtga
    21721 taatttgcga acagtaatga aatacatgtt atcattcttc tgttggtgac tttgccgact
    21781 cagatatata ctatctgtat gtcgtgcatt atatattaac gatacgcaga ggtgtgtata
    21841 tgggcagtgt tacaaagaaa ccgtcacctg ttgttattat taagaaaaaa agacgaattc
    21901 tttctcatca ggatgatgcc gtacaggcag ttcctgatga tataaaacca gcgccagtaa
    21961 tggaatttaa aaccgactca ttacctcctg aaataccagc cacagtggcc ggttccccgg
    22021 aacaacagaa aaaaacagga cgtaagaaga aaaaaaagaa gaacaataga tggaatcatg
    22081 agtttatccg acacagtctg gactgtgtta aaaaaacatt ccctcagtta cgggctgaag
    22141 aggggggata tcatgcattt aaaataggca tctcaaagga tgtcatggct tttatttcgg
    22201 ccagtcctga gtgtggactc actgtaaaag aatggagttg tgctgtaaga atgattactg
    22261 gcggttacaa atatctgcag cgtatatcag tctcaggtac tccgcgttat ggtctggatg
    22321 gcaaagttca tggaactgta acggaggaag aagcgctgta tgcgcaggca aaacttgaaa
    22381 aacacacgca gcgttataat gccaggatga aagagacaga agatgctcgt tgcaaccaat
    22441 catcgacaaa ctgtcacact ggacagcaat ttgaaggacg cctgcattca taacggggca
    22501 taattatgtg aagtgctgtc ccgctatgga atcagaattg agtaacgaca cgaggttttg
    22561 atgattactg ttattatttc tgaggcggat ggctggcgtg aatggaaaca ccgcgcccga
    22621 acaaaggatg cacagacagc catcatacgg gctatgaata aacattttcc acgatcttac
    22681 aattttatcc ctgatgatat tgataatgca cctgtattat ttgcagctgt aacacgtaca
    22741 ccgaacgtga aaataaccgg tcatatctgg aaacctatgt ggaacagggg aatttgctgg
    22801 aacgtcaaag gtccgccagt aatcatcacg ctcatccagg gggccgcttg gaattcggaa
    22861 aataaaccac gttaagacta ttttttagac aaatgacttt caggaatcgc taggatggcg
    22921 ggacaacagc tgttttggtg tccgaaatcg tacggtaaga ggaaaattat cgtcttaaaa
    22981 atcgattagt agacaatgcc gtccgttaag tgccaatttt cgattaaaaa ggcaccgttt
    23041 tgatggcgtt tttctatgtc cattatgttt tgatatatca gacagttact tcactaacgt
    23101 acgttttcgt tccattggac ttcagccccc taatccggtc agttcagctg aggatgacgg
    23161 ggatacagtc ccgccctgaa catcgcggat atagtttgcc tgacatgcag caagaataat
    23221 ggctgcaaga agcaataaaa taatccatgt tatttttttc atactgttcc ttgtatatat
    23281 ggactcaggc attcatccat aaaaacctga aatccaaagg ttgaaatcat ccatgaaaca
    23341 taaaattcta taacactatt tacatcttta acgtgataat gaaagcagtg tatccattct
    23401 caatatcatc tttaatattt tcaatagcca atctattatt ttcagggatt tttgatttgt
    23461 attcctccgg catatcatat gtccatgatg ctgaactatc tatcctgaat ccaggattca
    23521 gccaatgccc accatcaatg cccaaaatcc ataagccttt tttcgctgct tcattacaaa
    23581 cttctattgc agcttttggt gataacttca tagaagcatt tccttttaat tcaaaaaagg
    23641 catcaccact atcatataac accgtatgtt caaataattt attggtcatt tttatttccc
    23701 cattgaattc tcgaatcgtc cacccaaccc ggatctgtct tatcactaat ctgagtaacc
    23761 tcaccagtac gatcattgac aacaacatat ttaccaggag aaccatacac tgttgctgga
    23821 tcatttcgac ctaaatagtc tggaggtgtt ttcttcggac tacgcttatc aaaagatgta
    23881 ccagttgcac cgttagatag gggttgtacg ccggaaacgc cgaaatttcc gggaggcaca
    23941 aattttatgc tcggcaacct gtacgtaaga ccgccgttaa ccggacagca aagaaatagc
    24001 tgtttagagc gaaagaatca ctgcccgtaa cgtatcacat agctggtacg gataaattct
    24061 cacttactgc accataaacg tactcgtcaa caaccgccaa acatgcttca aaaatcaaca
    24121 aattcgctgt atcggaaatt tcggcgtttc cggcgtataa ccccctataa atatattgca
    24181 gcagccaaag tcggataaaa accacattca agaaattacg gtttcatcct ttgttcagca
    24241 gttgaaaccg taagtttctg ttcaaatgac ccgctggtcc atattgtacg tttcccaaac
    24301 gcagccctaa taaagtcatt cgatggcgta tttcttattg agaatatata cgcataaaat
    24361 agttataaaa acgcctagtc cctgaataaa tgatatatct tcctgcagga agaaccagga
    24421 caacagcaat gctaccagag gaataaaata gagcattgct cctgctatgt gaacgggaat
    24481 ccagcgtagg gaataaagat agaaacaaaa agccaaaaaa tattgtaaaa ttcctgacaa
    24541 aaacacaaga aatacagatt ctacaggcag ttgcagggat gtgccagtta gaacaataaa
    24601 aaaacaagca agaataaaag agaaagtcaa ctgcccggtt aacaacgtaa caggctcaaa
    24661 attcacaata agtcgtgatg agataacaac ataaaaggat gctgagagta cacctgcaac
    24721 aataagtata tatcctgtaa tattatcaat gcggtcattg atatcaggta gggcaaccat
    24781 tatactgcct gccattgctc cagtaagcaa taatataaag tgtaatggtg agttaatttt
    24841 aacgaaaaat aatataacag atagtataag aataaatact gactcaagtg aaaaaataac
    24901 ggctgttata ccagcagaaa taaatttcag gccatagagt gtgaatgtat acgccagaaa
    24961 tggctcaaaa attcctgttg aataggcaag gattgatttt tttgttaccg ggagcttttt
    25021 tctgctaatt gcgagaacaa accatgataa cattgcagca ctaccaactt gccagaaaaa
    25081 caatcctccg gcatccatgt tttcgagacc ttttttgctc atcactattg ctgctcccca
    25141 tgaaaaagca gcaagaaatg caaacagaac tcccttaatc atatttagtt atctcctcat
    25201 tataaagagg tttattttca aacgctcttg gtggaaatgg attaaaaaac tttgcttctt
    25261 catctacagg aataccaaga aattctccat aataaggatt atcaacagga aacttttcca
    25321 gtgagacata aaacaataca ttccagttaa aaatcatagg gtcattgcta tcaacattat
    25381 ggattattct ggagtcctga gtcagttctc cgggaattaa tacatctgta tgataaaagc
    25441 ctgaatagta atcactatta gtagaatgta tagggcagcc aaagcgattc attttattat
    25501 ctgagtgcca tgtggttgat attttttctg gatgagaata tcctccttta cctatggatt
    25561 gaatagtcat attacggata tcagataaag cttgctcctg atctttatag aatccttttg
    25621 caattgccag tctcataaaa tgtccaggtg catttacaga tataagcatt ccaccgggga
    25681 ttcgtcggtc atgatttcgg gttctgtgag cagaagagta aaaaatatta actccagctt
    25741 tatataccat cacgttttca ttttcctgca atggtatgct ttctgtgtag attatatctt
    25801 ctcttacagg ataatactca ggcatatgta aggaacatat atgtttctgt atatcaacaa
    25861 gttctttaga gggttttgca aaagcaattt tctgatgtat aaagtagata agatgagcac
    25921 ttacttcccc tttaagagct cgttctttga agataatccg ttctctacgt aaaaactcga
    25981 agagtttact atcattagta tacaatgatg gatcttttat tattgataag tgaaaatcaa
    26041 ggcctttgat tttcttacat gcaagtttac caaaaacaca cggttgattt actgatgccc
    26101 attttcttag ctctttttca attatattat catctgtctc tttgaatata aatttatgta
    26161 tagaatcaat atcctttcca aaggaaaaat cagaaggtaa ttgtggtaag ttgttaatat
    26221 gttgatgaag tggtttattc atattcacta tatatcctca catagtaaaa cttacatgta
    26281 cttacacgat gttaccttat ttttcaa
//
LOCUS       DAPOXO010000073        26257 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPOXO010000073 DAPOXO010000000
VERSION     DAPOXO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26257
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.073"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..903)
                     /gene="galU"
                     /locus_tag="ROH59_003607"
     CDS             complement(<1..903)
                     /gene="galU"
                     /locus_tag="ROH59_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDX4806045.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIK"
     gene            complement(1105..2118)
                     /gene="rssB"
                     /locus_tag="ROH59_003608"
     CDS             complement(1105..2118)
                     /gene="rssB"
                     /locus_tag="ROH59_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HDX4806046.1"
                     /translation="MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISQCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            complement(2210..3115)
                     /gene="rssA"
                     /locus_tag="ROH59_003609"
     CDS             complement(2210..3115)
                     /gene="rssA"
                     /locus_tag="ROH59_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HDX4806047.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVEKKMDELLPLVRTNI"
     gene            3228..3686
                     /locus_tag="ROH59_003610"
     CDS             3228..3686
                     /locus_tag="ROH59_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HDX4806048.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQ
                     DADYLIKTWHPSCGAAALRAELIAGFAHTEWLGLTVFEHCWQDGGDIGFVSFVARFTE
                     GGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            3736..4578
                     /gene="purU"
                     /locus_tag="ROH59_003611"
     CDS             3736..4578
                     /gene="purU"
                     /locus_tag="ROH59_003611"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HDX4806049.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDNLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            4738..4822
                     /locus_tag="ROH59_003612"
     tRNA            4738..4822
                     /locus_tag="ROH59_003612"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4772..4774,aa:Tyr,seq:gta)
     gene            complement(4839..5930)
                     /locus_tag="ROH59_003613"
     CDS             complement(4839..5930)
                     /locus_tag="ROH59_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA desaturase"
                     /protein_id="HDX4806050.1"
                     /translation="MNLFNPDRLITFPADDPQLVKQLQSGTKVYLAKSGDHRYADGWA
                     FVKMAVLIIACFSCYLLALFQRQWGLYLLWYLAMMFCAMLLAVNVVHDASHDAFLRGK
                     KTNARLNRWVAFPMGLDPDCWRVRHVRFHHGFTNIEFYDPDTAENGILRQTPWQRWRP
                     FMRQQHRYWPLVAALTFPWYIWVVDWLDRAGFTPVTRHLALRGFAGWGYFLAGKLAHC
                     ALCLIIPWLLSDFSFMTILLTYLLSQLLASLIFVTLIIGTHWAKGHTQLPPEEGKMPV
                     GRLAHTFATTFDWTPQPAWLGYWLGGINLHLTHHLFPHWHHRHYSALSRIIAQIASQQ
                     GLDYQLLTLADLLRLQQQFLRRMGEKPKV"
     gene            complement(5917..7041)
                     /locus_tag="ROH59_003614"
     CDS             complement(5917..7041)
                     /locus_tag="ROH59_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterol desaturase family protein"
                     /protein_id="HDX4806051.1"
                     /translation="MSDLLFPIISMVLLVLAEAGVLQFTGRQKVDWLDVIFNINSGHM
                     MLWLFRCLEVLCYGLVVNHFSLGLFDNVPVILLWLFTILAWDFGFYWLHRWHHEMRPL
                     WAVHVVHHQGEHYNLSLGVRNSWYSSLTSIPFFMLLAMLGVPLQVFLAVSIIHYSWQF
                     FNHNALTPKLGWLEKVLITPSHHRVHHLNQKQYADTNYGGTFLLWDKLFGSYSAGPEY
                     DVGYGVKNSRLSCNPMRESNLPFLRLMGFCSFGKAIEGRYQSSPWAVGAGVILLFMLV
                     LGYIQQYGYGIEFITSEQAVLFVLLAAGSVALGGMSDGQHWGMILWCSVTLSLLYFIV
                     YMCSWSTLLWKGLVGILLAHCLLFVIGVGRKSLRKQYEPV"
     gene            complement(7034..7636)
                     /locus_tag="ROH59_003615"
     CDS             complement(7034..7636)
                     /locus_tag="ROH59_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002432219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol phosphorylceramide synthase"
                     /protein_id="HDX4806052.1"
                     /translation="MSNSLLRLKQMLLGWGTVGVIYNFSDYLQGEGYQLTPSIIDNLI
                     AFSPSAVWLYLSFFFIVPLGYLSTPLCHLRWLARSMQISALVAGVFYLLWPTTMHYPS
                     FDQMGISAGALNRLIAIDSSQNCFPSLHAALTLLAVWAIAKKGNRWLTLMSVVWAIAI
                     AFSILQLRRHLFIDLVGGALLASICGWICATCEKRKTQYE"
     gene            complement(7633..8919)
                     /locus_tag="ROH59_003616"
     CDS             complement(7633..8919)
                     /locus_tag="ROH59_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoF synthetase"
                     /protein_id="HDX4806053.1"
                     /translation="MIPLMLIWRYFRTRRLHFTDREALENWQAKRLHQFRQNVLSHSP
                     WFQRYLTLPFNQWPMMDKALMMTHFDEMNTAGLKRDELLDCAMRSEQSRDFKPCVGKF
                     SVGLSSGTSGRRGLFVVSPHEQQMWAAGVLAKVLPDDLFAKERVALFLRADNNLYQSV
                     NNRWLSLDFYDLLAPFQAQLKLLQQRAPTIIVAPAQVLRALALEVMAGELTLKVKKVI
                     SVAEVLEPQDRELLRNVFHNVGEIYQATEGFLASTCRCGTLHLNEEFVHIEPQWLDEH
                     RFVPIVTDFTRTTQPIVRYRLDDVLVASEQPCPCGSATMAIARIEGRQDDQLQLPTRS
                     GDIQTVFADACSRVLAMTLPLTVDYRLLQTGSAQLTLIADCELWMLEHCREALNALFI
                     RQDIAVGQLIWSLELQTVPVSFTAKRRRIVRQWGRE"
     gene            complement(8916..9722)
                     /locus_tag="ROH59_003617"
     CDS             complement(8916..9722)
                     /locus_tag="ROH59_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDX4806054.1"
                     /translation="MAKITAFETGWCTHISCIALKGAGLKVCKFPARAWLLEVGDKRW
                     LWDTGYSSWFEHYTQSGVFRLYRQVTPVYFDPQQALVRQLSATGLAAKDVDAIILSHF
                     HADHIAGLRDFPDVSCICSGEGWRQVRTLRGVTALRQAFVPGLIPENFDSSLRFIESF
                     ASVNLPAQLAPFECGYLLPESNGEIILVPLPGHAAGHIGAFVLTDNGWTLLAGDAAWA
                     PANYRELRGPSPLAHLVMSDSHAYYHTLGQLHQLWQNGVVEIRLCHEGDL"
     gene            complement(9700..10716)
                     /locus_tag="ROH59_003618"
     CDS             complement(9700..10716)
                     /locus_tag="ROH59_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDX4806055.1"
                     /translation="MKILVTGATSGLGRNAVQYLLQSGESVVATGRNCEVGRSLTNAG
                     AQFVALDLTEATEDDCARLMDGCDAVWHCAAKSSPWGDKTAFWLANVKVTHTLAQAAG
                     RLNIPRFIHISTPAVYFDFQHHYDLPETYLARAFSSHYASSKYAAEQVIAGAVSRYSA
                     TRFILLRPRGLFGPHDQVIVPRLMQQLQQGGGCLRLPRGGDALLDLTFVQNVVYAMRL
                     ATNVEGLRSGSIYNISNHQPQQLSVMLDALLHQQLGLSYRIAAVPWSLLSLIARGLEL
                     YGKCVNQEPVITRYSAGTLCFDMTLSAQKAITELGYRPRFSMEQGIAITGQWLREHGK
                     NNRI"
     gene            complement(10713..11720)
                     /locus_tag="ROH59_003619"
     CDS             complement(10713..11720)
                     /locus_tag="ROH59_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001385314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDX4806056.1"
                     /translation="MARPNQPTISAALKIIATGIALPPDQITSKQLDVQLNKPVGYVE
                     RRSGICWRYFARNDASQAELAAEALHNALVAAALNPSDIDLLICASAIAVQALPCSAI
                     HILKAAAMPVGVAGFDINSSCVSFISALEVAAGLLNCGAYRRIAIVSADIASRGIDWD
                     HEESSLIFGDGAACAIVERGDGRSGIIASLIEMYPEGSELCEIRAGGTRRNPRSGVSD
                     SDFLFHMQGKPLFRFASSLIEDYFSRLLQKSSLQLSDIGTVVPHQASHLSLEHMRKRL
                     RVPESALIDVYRFYGNQVAASIPTALHEAVISGRFTADKPVMLIGTAAGLTLAGMVLL
                     P"
     gene            complement(11848..12525)
                     /gene="narI"
                     /locus_tag="ROH59_003620"
     CDS             complement(11848..12525)
                     /gene="narI"
                     /locus_tag="ROH59_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDX4806057.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(12525..13235)
                     /gene="narJ"
                     /locus_tag="ROH59_003621"
     CDS             complement(12525..13235)
                     /gene="narJ"
                     /locus_tag="ROH59_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDX4806058.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLPKEDAHALG
                     IFLRDLTTMDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLAQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVLFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(13232..14770)
                     /gene="narH"
                     /locus_tag="ROH59_003622"
     CDS             complement(13232..14770)
                     /gene="narH"
                     /locus_tag="ROH59_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDX4806059.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTICSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            complement(14767..18510)
                     /locus_tag="ROH59_003623"
     CDS             complement(14767..18510)
                     /locus_tag="ROH59_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HDX4806060.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAREAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVMGQKSNGNPEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKELGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
     gene            complement(18903..20294)
                     /gene="narK"
                     /locus_tag="ROH59_003624"
     CDS             complement(18903..20294)
                     /gene="narK"
                     /locus_tag="ROH59_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HDX4806061.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWI
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
     gene            20633..22429
                     /gene="narX"
                     /locus_tag="ROH59_003625"
     CDS             20633..22429
                     /gene="narX"
                     /locus_tag="ROH59_003625"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HDX4806062.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALIRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQSDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADTHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWVQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            22422..23072
                     /gene="narL"
                     /locus_tag="ROH59_003626"
     CDS             22422..23072
                     /gene="narL"
                     /locus_tag="ROH59_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HDX4806063.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(23073..24467)
                     /gene="ychO"
                     /locus_tag="ROH59_003627"
     CDS             complement(23073..24467)
                     /gene="ychO"
                     /locus_tag="ROH59_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HDX4806064.1"
                     /translation="MSRFVPRIIPFYLLLLAAGGTANAQSTFEQKAANHFENSNDGLP
                     DLGMAPEHHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDDGLVSNV
                     GVGQRWARGSWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVVESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSEEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            24652..25005
                     /gene="ychN"
                     /locus_tag="ROH59_003628"
     CDS             24652..25005
                     /gene="ychN"
                     /locus_tag="ROH59_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HDX4806065.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQENNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            complement(25049..25744)
                     /gene="chaC"
                     /locus_tag="ROH59_003629"
     CDS             complement(25049..25744)
                     /gene="chaC"
                     /locus_tag="ROH59_003629"
                     /EC_number="4.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-specific
                     gamma-glutamylcyclotransferase"
                     /protein_id="HDX4806066.1"
                     /translation="MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGRTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENYPDGVLRPGFA"
     gene            complement(25893..26132)
                     /gene="chaB"
                     /locus_tag="ROH59_003630"
     CDS             complement(25893..26132)
                     /gene="chaB"
                     /locus_tag="ROH59_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HDX4806067.1"
                     /translation="MSYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKEDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKSSNR"
BASE COUNT         6628 a         7071 c         6425 g         6133 t
ORIGIN      
        1 cttaatgccc atctcttctt caagccaggc tttaaattcc gtgccaaggg tgttatgacg
       61 aataccgtat tcaacgaagg cctgcatgta acctaattta ttaccgcagt catggctctt
      121 ccctttcata tgataggctt caaccgtttc tttttcgatc agcatatcaa ttgcgtcggt
      181 gagctgaatt tcatcaccag ctccaggagg ggtttttgcc agcaacggcc aaatatccgc
      241 gctaagtacg taacgaccca caatagcgag attagacggc gcaacatccg cttttggttt
      301 ttcaaccacg ccaaccatcg gtacgctttc acccggcgct aattcaacgc ctttgcaatc
      361 cacaacgcca tatgcggtca catcagcaac cggttcaacc atgatctggc tatgacccgt
      421 ttcatcaaag cggcggatca tctctgccag gttatcctgt gataaatcgg attcatattc
      481 atccagaata acgtcaggca aaataacagc cacaggttca tcacccacta ccgggtgagc
      541 acacaatacc gcgtgtccca ggcctttcgc cagcccctga cgaacttgca taatagtcac
      601 gtgcggcgga caaatagact gcacttcatc aagcagttga cgttttacac gtttttccag
      661 cattgcttcc agttcaaaac tggtatcaaa gtggttttca atagagtttt tagatgagtg
      721 agtaaccagc acaatttcag taatgccagc cgcaatacat tcattcacga cgtattgaat
      781 taatggctta tcgacaagtg gcagcatctc tttcgggatg gctttcgtcg ccggcaacat
      841 cctggttcct aatcccgcta cggggataac ggcttttttg actttcgtat taatggcagc
      901 catttaaatt ctcctggact gttcgtgttt tgaacgtgtt catatttctg tatcgcatcc
      961 cagtatatca gcaccccgaa ggggctaagt tctgaaaagg aggcgagtta gcataattaa
     1021 gacaattact tatacgaata gcgacgatag taccaccagc cgacattagc aggtaatgca
     1081 aatttagccc gtgttatcgt ttgctcattc tgcagacaac atcaagcgca gccgaccacc
     1141 ggttccccat atttggcatt gccaggcatc gcatcgctgg ctcaattgat tcaaataagc
     1201 gttacctaaa gtgcctaacg gaacaccatt actgatttgc acctgatgtt cgccggtatt
     1261 taacgtcgca ttcagacccg cagaaaccag aatgagattt ttcagttcgc gatgataata
     1321 gccaactaat agcggaaact gccccggcag attggcctga cggagtaaat ggtttacctg
     1381 cttcaataac gcgcccaact ctggcaaccg ttgattttgg tgtgcaagct gttcctgtaa
     1441 taatccgtta aacaatgcgc gtaataacaa ggcagcaagt acgccattat gtccagctcg
     1501 ggtgacatca aggcaataaa atgccagatc gttttccgaa agtgcggcaa tatcaagcac
     1561 caggccgggt ttgtccgcgg caactaattg acgataatta acccggcatt gggaaatcac
     1621 ctgctgaacc ggcggttgta gttcctgtaa taatttcgcc gctgcagcag ggttatcaac
     1681 cattgcatcc cagtcgcgaa aaagcctttc ctcttcctca acgcgggaat taaacatgct
     1741 gggatagaga caggcaaaaa ccatctcgcg caagcgattc agatctttaa ccggtttcag
     1801 caaaacatct tcaacgccca gacgtaacgc tttggcaata tctgccatat tttcagtggc
     1861 agatatcacc agaactggtg tctggtcacc tctgttgcgt atatgttcca gcagtttaag
     1921 cccgttcatt cgtggcatcg cgatatcaca tatcatcagg tctggagtga aacctcccag
     1981 caactcaagg gcatccaccc catcagccgc cagtaccgtt gtcgctccca atgaggaaaa
     2041 ccacgaatcc agaagcgagc gaaatacctg ctcatcttca acaatgagaa tctgttttcc
     2101 gaccaatggc tgcgtcatgt tctctcccct gactggcttt actcaatagt ggcatgctat
     2161 tgccacctac gcctgtcaga attaacttaa gtgtagataa aaattctggt caaatgttgg
     2221 tgcgtaccaa cggcaaaagt tcgtccattt tcttttccac tgccagctgt ccggccgcaa
     2281 tggcagcgtg cgcgcgatgg aaatcaagcg tagatatttg cgggcaaaca ggttgaatca
     2341 gaatatcggg cggatcacct gccatgcggt tccttttaag gcggttctcc agcacctgga
     2401 tagaagtggt cataatctct gttgccgttg gcgctgtcac cgcccgacgt gtcgttatgc
     2461 tgcctaacct ttctttcaga cgcgcatgcc acggcagaga atcaccattc tcgctatttt
     2521 cttcactgac attaaaggag agcaaatctt gttgcatcaa atgagcatcg tgctgcaggt
     2581 cgaccgctat cacaatatca gcccccaatg cacgcgtgag ggaaatagga attgggttaa
     2641 ctacagcgcc atcaaccagc cagtagccgt tatgcgcaac gggtgccatt agtcctggaa
     2701 tactgcatga tgcacgaata gcaagatgga gatcgccttc agtaaaccat aattcacgcc
     2761 cagtacttaa attggtggca acagccgcga agcgacggga acaattttcg atctctgttt
     2821 ccggcattat ttcgcgatat tgattgaaga cacgctcgcc gcgcagtaac ccaccgcgct
     2881 gccaggagag atccatcagg cgtaaaacat cccaataact gaaagaggtc acccaatctt
     2941 ccagcgcaga taatcgatcg catgcatagg cagcgcccac cagcgaacca attgaacatc
     3001 ctgcaacgat atcaatttca atacccactt tttttagcgc attaattacg ccaatatgcg
     3061 accaacctct tgccgcgcca gatcccagcg ccagccctat ttttatcttt ctcattattc
     3121 ccgcaagatt cccctggaat gcaatcgtag ccacatcgct actgctcggt taacatagtg
     3181 ctactcaggc ggttaatacg ccgttattgt ttccagggag attatttgtg tctcagcttt
     3241 gtccctgtgg tagtgctgtc gagtatagcc tatgttgcca cccttatgtg tctggtgaaa
     3301 aggttgcacc tgatccagaa catctcatgc gttcgcgtta ctgcgctttt gtgatgcaag
     3361 acgcagatta tttaataaag acctggcatc catcttgtgg agcagcggcg ttacgtgccg
     3421 aattgattgc cggatttgcg catactgaat ggttgggatt gaccgtattt gaacattgct
     3481 ggcaggacgg cggcgatatc ggatttgtca gttttgttgc tcgatttacc gagggtggca
     3541 aaacaggtgc aataattgaa cgttcgcgat ttttgaaaga aaacggtcaa tggtactata
     3601 ttgacggtac acgtccgcag tttggccgca acgatccctg cccttgtggt tcaggtaaaa
     3661 aatttaaaaa gtgctgcggc caataatggt tgacggtacg gtttagcaaa cactctcaac
     3721 aaggtttttc cagcaatgca ttcactccaa cgtaaagttc tgcgtactat ttgtccggac
     3781 caaaaaggtc tgatcgcacg tattaccaat atttgctaca agcacgagtt aaatatcgtg
     3841 cagaacaatg aatttgtaga tcatcgtacc gggcgctttt ttatgcgcac ggaactggaa
     3901 gggattttta atgattccac cctgctggca gatctcgata gcgcattgcc agaaggctcc
     3961 gtgcgtgagc tgaatcctgc cggtcgtcgc cggatagtga ttctggtcac taaagaagca
     4021 cattgccttg gcgatttgct gatgaaagcc aattacggcg gcctggatgt cgaaatcgcg
     4081 gcagttattg gtaaccacga taatttacgt tctctggttg agcgttttga tattccgttt
     4141 gagctggtaa gccatgaagg gttaagccgc aacgagcacg atcaaaagat ggcggatgcc
     4201 attgatgctt atcaacctga ctatgtggtg ctggcgaagt atatgcgggt attaacgccg
     4261 gaatttgtgg ctcgcttccc gaataagatc atcaatattc accattcctt cctgccagcg
     4321 tttatcggcg cacgtcctta tcaccaggcc tatgagcgtg gcgtgaagat tattggcgca
     4381 accgctcact atgtgaatga caatctggac gaaggtccaa tcatcatgca ggacgttatt
     4441 catgtcgatc atacctacac agctgaagat atgatgcgcg caggtcgtga cgtcgagaaa
     4501 aacgtcttaa gtcgtgcgct atacaaagta ctggcgcagc gcgtctttgt ttacggtaat
     4561 cggacgatta ttctttaatc gtcagccaaa ataactggtt agctttaatc cgttacggat
     4621 gaaaatcacg caaccagttc atttttctca acgtaacact ttacagcggc gcgtcatttg
     4681 atatgatgcg ccccgcttcc cgataaggga gcaggccagt aaaaagcatt accccgtggt
     4741 ggggttcccg agcggccaaa gggagcagac tgtaaatctg ccgtcatcga cttcgaaggt
     4801 tcgaatcctt cccccaccac catcactcga ttccattatc aaaccttcgg cttctccccc
     4861 attcgccgta aaaactgctg ctgtagcctc aacaaatccg ctaacgtcaa caactgataa
     4921 tccagacctt gctggctggc aatttgcgca ataatgcggc ttagcgccga ataatggcga
     4981 tgatgccagt gaggaaacag atgatgggta aggtgcagat taatcccacc cagccagtag
     5041 ccaagccatg caggttgcgg cgtccaatca aaggtggtag caaaggtatg cgccagtctg
     5101 cccacgggca ttttgccctc ttctggtggt aactgcgtat gtcccttcgc ccagtgcgtt
     5161 ccaataatca acgtcacaaa aatcaatgac gccagcagct ggctgagcag ataagtcagc
     5221 aggatggtca taaaactaaa atcagacaaa agccagggaa ttatcagaca cagcgcacaa
     5281 tgcgccagtt tcccggctaa gaaatatccc cagccagcaa agcctcgcag ggccagatgt
     5341 cgcgtgaccg gcgtaaaccc tgcgcgatcg agccagtcca ctacccagat ataccaggga
     5401 aaggtgagcg cggcgaccag tggccaatag cgatgttgct ggcgcataaa aggtcgccac
     5461 cgttgccacg gcgtctggcg aagaatgcca ttttctgctg tatctggatc gtaaaattca
     5521 atattggtaa aaccgtgatg aaagcgaacg tggcgcaccc gccagcagtc cggatctagc
     5581 cccataggaa aagcaaccca ccggttaagc cgggcattgg tctttttacc acgcaaaaac
     5641 gcatcatgcg aagcgtcatg caccacattg accgctaaca acatggcgca aaacatcatc
     5701 gcgagatacc acaacagata cagtccccat tgacgttgaa ataacgccag taagtaacag
     5761 gagaaacaag caataatcaa caccgccatt ttgacgaatg cccatccgtc ggcataccga
     5821 tgatcgcctg atttcgccag ataaactttc gtaccgcttt gcagttgttt caccagttgt
     5881 ggatcatcgg caggaaaagt gattaacctg tcgggattaa acaggttcat actgtttcct
     5941 tagcgattta cgtcctacgc cgattacaaa taacaggcaa tgggccagca gaatacccac
     6001 taatcccttc cagagcagag tactccatga acacatatag acaataaaat agagcagtga
     6061 caacgtcaca gagcaccaca aaatcatacc ccaatgctgc ccgtcgctca tgccccccag
     6121 cgcaacggag cctgccgcca gcagaacaaa taatacggct tgctcgctgg taataaactc
     6181 aatgccatag ccatattgtt gaatgtagcc aagcaccagc ataaacagca ggatcacccc
     6241 tgcccctacc gcccatggag aactctggta gcgaccttca atcgctttgc caaatgagca
     6301 aaagcccatt aagcgtaaaa atggcagatt actctcgcgc atcgggttac aggacaagcg
     6361 actatttttt acgccgtagc ctacgtcgta ttccggcccg gcactatacg aaccgaaaag
     6421 tttatcccac aacaaaaagg tgccaccgta attggtatcg gcatattgct tttgattcag
     6481 atgatggacg cgatgatgcg aaggcgtgat cagcactttt tccagccagc ccagtttcgg
     6541 cgttagtgcg ttatggttaa aaaattgcca actatagtga ataatagaaa ccgccaaaaa
     6601 gacctgtaac ggcacaccaa gcatcgccag cagcataaaa aacgggattg aggttaacga
     6661 ggagtaccac gagttccgca cgcctaatga caggttgtag tgttccccct gatgatgcac
     6721 cacatgtacc gcccacagcg ggcgcatttc gtgatgccag cgatgtagcc agtaaaagcc
     6781 gaaatcccac gccaggatag taaacaacca cagcaggatc accggcacat tatcaaacag
     6841 tccaaggctg aagtgattga ccaccaggcc atagcagagc acttccaggc agcgaaataa
     6901 ccacagcatc atatgaccgg agttgatatt aaaaataacg tccagccagt ccactttttg
     6961 ccgcccggtg aattgcaaca cgcccgcttc ggctaacacc aacagcacca tcgatatgat
     7021 ggggaataat aaatcactca tattgtgtct tccttttctc gcatgttgcg catatccaac
     7081 cgcaaatcga cgccagcaac gcgccgccta ctaaatcgat aaataaatgt ctgcgtaatt
     7141 gcagaatcga aaaggcgatt gctatcgccc agaccacgct cattagcgtc agccaacggt
     7201 tccccttttt agcaatcgcc cataccgcca acagcgttag cgcggcgtgt aaggagggaa
     7261 aacagttctg gcttgagtca atggcgatca gcctgttgag tgcgcccgcg gatatcccca
     7321 tctgatcaaa cgagggataa tgcatggttg tgggccagag aagataaaat acgccagcca
     7381 ccagtgcgga aatttgcatt gaacgggcca gccagcgcag gtggcaaagt ggcgtggata
     7441 aataacctaa cggcacaatg aaaaaaaacg agagatacag ccacacagcg gagggggaaa
     7501 acgcaatcaa attatcaatt attgacggtg ttaattgata tccctcacct tgcaggtagt
     7561 cgctaaagtt gtagataacc ccaacagttc cccagcccag cagcatctgt ttcaggcgta
     7621 gcagtgaatt gctcattccc gcccccactg acgcacaatg cgccgccgct tggctgtaaa
     7681 agagactggc acagtttgca gttccagcga ccaaattaat tgcccgacag cgatatcctg
     7741 gcgtataaac aaggcattca acgcctcccg gcaatgctcc agcatccaca gctcgcaatc
     7801 ggcgattaac gtcaattgtg ctgacccggt ttgtagcagg cgataatcga ctgttagcgg
     7861 cagtgtcatt gccagcacac gactacaggc atcggcaaaa acggtctgaa tatcgccgga
     7921 tcttgttggt agttgcagtt ggtcatcctg ccgcccttcg atacgcgcaa tcgccattgt
     7981 tgcactgcca caggggcatg gctgttcgct tgccaccagc acatcatcca gtcgataacg
     8041 cactatcggc tgtgtggtgc gggtaaagtc tgtgacgatc ggcacgaaac ggtgctcatc
     8101 cagccattgc ggttcaatgt gaacaaactc ttcgttgaga tgtaacgttc cacaccggca
     8161 ggtggaagcg agaaagcctt ctgtcgcctg ataaatttcc cccacattgt ggaacacgtt
     8221 gcgcagtaat tcccgatcct gcggctccag aacttccgcc accgaaatca cttttttgac
     8281 ctttagcgtc aattcgccgg ccatcacctc cagcgccagt gcgcgtaata cctgagctgg
     8341 cgcgacaata atcgtgggcg ctcgctgttg gagaagtttg agttgcgcct gaaatggcgc
     8401 tagcagatcg taaaaatcga gacttaacca gcgattattc acgctttgat acaggttgtt
     8461 gtccgcgcgc agaaacagcg ccacccgctc tttggcaaat aaatcatcgg gcaacacttt
     8521 tgccagcaca ccggcggccc acatctgttg ctcgtgcggg ctaacaacaa aaagtccacg
     8581 acgcccggat gtacctgatg aaagcccaac gctgaactta ccaacgcagg gtttgaaatc
     8641 acgactctgc tcactgcgca ttgcacaatc gagaagttcg tcgcgcttta aacctgcggt
     8701 attcatctca tcgaagtgcg tcatcattaa cgctttatcc atcattggcc actgattaaa
     8761 gggcaacgtc agataacgct gaaaccacgg gctatgagat aagacatttt gccggaactg
     8821 atgcagcctt tttgcctgcc agttttccag tgcctcgcga tcggtgaaat gcagcctgcg
     8881 ggtacggaag tagcgccaga tcaacatcaa cgggatcata aatccccctc atggcacaaa
     8941 cgaatctcca ccacaccgtt ttgccaaagc tgatggagtt gcccaagcgt gtggtagtag
     9001 gcgtggctgt cggacataac cagatgcgcc agtggtgaag gccctcgcag ctcccggtag
     9061 ttagctggcg cccatgccgc atcgccagcc agtaaagtcc agccgttgtc ggttaacaca
     9121 aacgcgccaa tatgtccggc agcatgtcct ggaagcggca cgagaataat ttcgccattg
     9181 ctttctggca gcaaatagcc gcactcaaac ggtgccagtt gcgcgggcaa attcaccgat
     9241 gcgaaacttt caataaagcg cagtgaggag tcaaaattct ccgggattag ccctggcaca
     9301 aaggcctggc gcagcgcagt gacaccacgc agagttctta cttgccgcca gccttcacca
     9361 gaacagatgc aggaaacatc agggaaatca cgcaggccag caatatgatc agcgtgaaaa
     9421 tgcgacagaa taatcgcatc aacatctttc gctgcgaggc cggtggcaga aagttgtcgc
     9481 accagcgcct gttgcggatc gaaataaacc ggcgtgacct ggcgataaag acgaaacaca
     9541 ccagattgcg tgtagtgttc gaaccacgat gaatagcctg tgtcccacag ccaccgtttg
     9601 tcgcccacct ccagcagcca ggcgcgggcg gggaatttgc acactttcag ccctgcccct
     9661 ttcagcgcaa tacagctaat atgggtacac cagcccgttt caaatgcggt tatttttgcc
     9721 atgttccctc agccattgtc ccgtgattgc aataccttgt tccatcgaaa agcgtgggcg
     9781 atatcccagc tctgtaatgg ccttttgcgc actcagcgtc atatcgaaac agagtgttcc
     9841 ggcgctgtat cgtgtgataa caggttcctg attaacgcac ttcccataca gttccaggcc
     9901 acgcgcgatc agagaaagca gcgaccaggg aacagcagca atgcggtaac tcaagcccag
     9961 ttgctggtgc agcaaggcgt caagcatcac cgatagctgc tgcggctggt gattgctgat
    10021 gttgtaaata ctgcccgagc gtaagccttc aacgttcgtt gccagccgca tggcatacac
    10081 cacgttttgc acgaacgtga gatccaataa cgcgtcgccc ccgcgcggca aacgtaagca
    10141 accgccgccc tgttgcaatt gctgcatcag acgaggaaca attacctggt catgggggcc
    10201 aaacaaacca cggggacgca aaagaataaa tctcgtggca gaatatcgag aaacagcgcc
    10261 agcaataacc tgctcagcgg catatttact gctggcataa tggctggaga atgctcgcgc
    10321 aagataagtt tctggcaggt catagtgatg ttgaaaatca aagtaaaccg caggcgtgga
    10381 gatatggata aaccggggaa tattcagcct gcctgccgcc tgtgccagag tgtgggtcac
    10441 tttgacattg gcaagccaga acgccgtttt gtcgccccag ggcgaggact ttgccgcaca
    10501 gtgccagacg gcatcgcagc cgtccatcag gcgggcgcag tcatcctcgg ttgcctcggt
    10561 taaatcgaga gccacaaact gtgcgcctgc gtttgtcagg cttctgccaa cctcacaatt
    10621 tcgccctgtt gccacaaccg actcacccga ttgcaacaaa tattgcacgg catttcgccc
    10681 aaggccgctg gtcgcccctg ttacgaggat cttcacggta aaagcaccat gccagccagc
    10741 gttagtcccg ctgccgtgcc aatcaacatt acaggtttat ccgctgtgaa acgaccgcta
    10801 atcactgctt catgcagcgc cgtggggata gaggccgcga cctgattgcc gtaaaaacga
    10861 tacacatcga tgagcgcaga ttccggcact cgcagccgtt tacgcatatg ttcaagggaa
    10921 agatgactgg cctgatgcgg aacgaccgtg ccgatatcag acagttgcag gctgcttttt
    10981 tgcagcaacc gagaaaaata atcttcaata agcgaagaag caaaacgaaa cagcggtttc
    11041 ccctgcatat gaaaaagaaa gtcgctatca ctcacaccag agcgaggatt acgccgcgta
    11101 ccgccagcac gaatttcaca cagttcgctg ccttcgggat acatttcgat caggctagcg
    11161 ataatcccgc tgcgcccatc gccccgctca acaatcgcgc acgccgcgcc atcaccaaaa
    11221 attaatgaag actcttcatg atcccagtcg ataccgcgtg aagcaatatc tgccgaaacg
    11281 atggcaatgc gtcgatatgc tccacagttt aataatccgg cagcgacttc aagagcggaa
    11341 ataaagctca cacagctact gttgatatca aacccggcaa cgcctacggg catggctgcg
    11401 gctttaagaa tatgaattgc gctacagggt aatgcctgta cggcaatggc cgatgcacaa
    11461 attagcagat caatatcaga aggatttaag gctgccgcta ctaacgcatt atgtaaagcc
    11521 tctgccgcca gttcggcctg gctggcgtcg ttgcgggcaa aatagcgcca gcaaataccg
    11581 gaacgtcgct caacatagcc aactggctta tttaactgaa catccagttg tttagaagtg
    11641 atttgatcag ggggtaaggc gatccccgtg gcgattattt ttaacgccgc ggagatcgtc
    11701 ggttgattag gtcgagccac ggtcagtgct ccttcactgc tccataggtg gaccaatcat
    11761 atagatgaag tacgtttccc tacaatccga aaaatcggca gtgtgtaacc gccgatgttt
    11821 ggtttagata atgtttggtt tagataatta gtgacgagcg cgcaccagct gatacttacg
    11881 cgtcagatac tccaccggga cactccagat gtgtaccaga cgcgagaacg ggaacagcag
    11941 gaataacgtc atccccaaca ccaggtgcag acggaagata aacgccacgc catcaagatg
    12001 ttgagaagcg ccaccgtgga aggtcactac cgactgcgcc cagccaacca gtttcatcat
    12061 ctcgctaccg tccatatgct gagcagagaa cggaatggtc agcaggccca gcgcgcactg
    12121 gataacgagc agcgacagga tcaggatatc cgctccggta gtcgttgcac gcacgcgtgg
    12181 gctgaacaga cggcgtttca acaacagcac gccgccaatc agacacagta cgccgctggc
    12241 accaccagca aacatcgcca ttttctgctt cacttcaatc ggcagccagg cttcatacat
    12301 ccagtgcggc gtcagcatac cgaagaagtg accgacaaaa atccccagaa taccgatatg
    12361 gaacaggttc gacgccagat tcatcccttt gcgatccagc atctggctgg acgccgcgcg
    12421 ccaggtatac tgcccgtagt cataacgcag ccagctacca atcaggaaga ccgccccggc
    12481 tatgtacggg tagatatcaa agaagaacat attcaggaat tgcattagtg ctgtcctccg
    12541 gtggtgatat tcagatattg cggcgcgacg gcaccggcaa agcgacgctg atgagcagtg
    12601 attgctgaat caccgcagcc tttgtcagca aagaatttaa cctgctcttc ttcccagact
    12661 gcatccagcg cctgcggcgt atcgtcgcgc gcttcgtcgg caattttttc cgccactttg
    12721 tcgctgtcga ttgcggtatt cgccagtttc agcagcagat caaacagcac ggcataacgg
    12781 ctttcacgct gttgcagacg cgcactcagc aatgccagaa tcggcgcaat atctttcaaa
    12841 ccctccacgg cttcgctttg cggcagctgc gccaggtact ccagatacag cggcagatgg
    12901 tcgggcaatt cgcggctgtt taactgcaag ccgtgctgct cgtactgcgc cagcagatcc
    12961 accatcgcct ggccgcggtc acgggattca ccgtgaacat gttcaaatag caacagtgac
    13021 gtggcgcggc cacggtcgaa cagttcgctg tactgcgcct gggcatcgag cggatccatc
    13081 gtcgttaaat cgcgcaggaa aatgcccagc gcatgggcat cctcttttgg cagatttttc
    13141 gacgcggcaa tcgcctcaaa catctcttgt tgatgctgcc ataaggcagc atccggatat
    13201 tcaaggagac gcgatacaat cacgagttcg atcatgggtg cggctccgtt ttgctggtta
    13261 cgtcgatggc atcgatacgg cggctgttga acagattgaa tttggtatct gaaccgtggc
    13321 agccatcacc aaaggtaaag ccgcagccat ttttctccgg gaaggcttcc cgcgccagtt
    13381 cacgatgact gctcggcacc acaaagcgat cttcgtagtt ggcaatagcc agataacgat
    13441 acatctcctg tgcctgggct tcggtcagac cgacctcttc cagcgcacgg gtatcgactt
    13501 taccgtcaac ggtttcagca cgtttgtaat gacgcatcgc cagcatacgt ttcagcgcgc
    13561 gcagtaccgg tttggtatca ccggcggtca gcagattcgc cagatactgt accggaatac
    13621 gcaggctttc gacgtctggc agaatgccgt tgctgcccag ttcacccgcg tctgccgcag
    13681 actgaatcgg cgacagaggc ggcacgtacc agaccatcgg caatgtgcga tattccggat
    13741 gcagcggcag cgccagtttc cattccatcg ccattttata aactggcgac tgctgcgcag
    13801 cctcaataac gctcagcgga ataccgtctt taatcgcctg ctcgatgact ttcggatcgt
    13861 tcggatcgag gaacacatcc agctgacgct ggtagagatc tttctcgttc tcggtacttg
    13921 ccgcacgttc aatcgcgtcg gcatcgtaca gcagcacgcc aagataacgg atacgaccga
    13981 cacaggtttc tgaacatatt gtcggctggc cggcttcaat acgcggatag cagaagatgc
    14041 acttctcaga cttaccgctc ttccagttga agtagatttt tttgtacggg catccggtga
    14101 tgcacatacg ccagccacgg catttatcct ggtcgatcag gacgatgccg tcttcttcac
    14161 gcttgtaaat cgcaccgctc gggcaggtcg ccacacatgc cgggttcaga cagtgttcgc
    14221 acaggcgcgg caaatacatc atgaaggtgt tttcgaactg gctatacatc gccttctgga
    14281 tgttgtcgaa gttcttgtct ttcgccagct tgtcaaactc accgcccagg tcatcttccc
    14341 agttcggccc tttttcgatt ttcgccatcc gttcgccggt aatcagcgaa cgcggacggg
    14401 caatcggctg tgatttgctg ccttccggcg cggtatgcag gttctgataa tcaaaatcaa
    14461 acggctcgta ataatcgtcg atccccggca gatgcgggtt agcgaagatt ttacccagca
    14521 gcatggcacg gttacccatg cgcggctgca gtttgccgtt gattttacgg atccagccgc
    14581 ctttgtattt ttcctggttt tcccagtcag tcgggaagcc ctggcccggc ttggtttcca
    14641 cgttgttgaa ccacgcgtat tccacgcctt cacggctggt ccagacgttt ttacaggtca
    14701 ctgaacaggt gtggcagccg atgcacttat cgagattcag caccatgccg acttgtgaac
    14761 gaattttcat tttacgctct cctgtacctg gtcattgcct tcgccatcta accagtcaat
    14821 gttcttcatc ttacgcacta caacaaactc atcgcggtta gaacctacgg tgccgtagta
    14881 gttaaagcca tatgccagat gggcatagcc gccgatcata tgcgtcggtt tcggcgtgat
    14941 acgggtgacc gagttatgga taccaccacg ctgttgggta atttccgaac caggcaggtt
    15001 aacgatacgt tcctgcgcgt ggtacatcat ggtcatccct gccggaacac gctggctgac
    15061 aaccgcacgg gcagtcagtg caccgttgct gttgaagact tcaatccagt cgttatcggc
    15121 gatacccagc tctttggcat cggcttcact cagccagacc accggaccac cgcgacctaa
    15181 agtcagcatc aacaggttgt cgctgtaggt ggagtggata ccccacttct ggtgtggcgt
    15241 caggaagttg agcgcttttt ccgggttgcc attggatttc tggcccatca cttctttcac
    15301 cgaacgggtg tcgatcggcg gacgataaac cagcaggctt tcaccgaaat cacgcatcca
    15361 ttggtgatcc tgatacagct gctgacggcc agagagcgta cgccacggga tcagctcgtg
    15421 aacgttggtg taaccggcgt tgtaagaaac gtgttcatct tcaaggccag accatgtcgg
    15481 gctggagatg attttgcgcg gctgtgcctg aatatcgcgg aagcgaatct tctcgtcttc
    15541 tttattcagc gccagatgcg tatggtcacg gccggtaaac tcgctcaggg cagcccaggc
    15601 ttttacagct acctgaccgt tggtttccgg tgccagcgtc aggatcatct ctgccgcatc
    15661 aattgcggta ttgagcatcg gctgaccttt tgccggacct tccgcttttg tgtagttgag
    15721 cttacgcagc agatccatct cgctctgggt gttccaggca atccctttac cgccgttacc
    15781 gattttctcc atcagcgggc cgatagaggt aaagcgttcg taagttgccg gataatcgcg
    15841 ctctacgacc ataatgtgcg gtgcggtttt acctgggatc aggtcgcatt cgcctttttt
    15901 ccagtctttc acatccagcg gttgcgccag ttcagcggca gagtcgtgct ggataggcag
    15961 cgtgacgatg tcagtttctt tacccagatg accaacgcac acttcggaga atttcttcgc
    16021 gatggctttg tagatttccc agtcgctttt cgcttcccag gccggatcga ccgccgcaga
    16081 cagcgggtga ataaacggat gcatatccga agtattcatg tcgtcttttt cgtaccaggt
    16141 cgccgtcggc aaaatgatgt cggaatagag acaggtgctc gacagacgga agtccagcgt
    16201 caccaccaga tccagcttgc cttccagacc gttgtcctgc cagtccactt cttccggctt
    16261 cacgccgccc tgctgcccca ggtctttgcc ctggataccg tgctccgtcc ccagcaggta
    16321 cttgagcata aactcatgac ctttaccgga agaaccgagc aggttagaac gccagatgaa
    16381 caggttacgc gggtggtttt taccgttttc cggctgttcc gcagcgaaac ggatagaacc
    16441 ctctttcagg gatttcaccg tatagtccac cggattcatc ccggcttttt ctgcttcgcg
    16501 agcgatagtc agcgggttag tgcctaactg cggcgcagac ggcagccagc ccatgcgttc
    16561 tgcacggacg ttaaagtcga tcaagtgtcc ggtatagcga gatttatccg ccatcggcga
    16621 cagcagttct tccgcagtca cggtttcata acgccactgg ctggagtggt tatagaaata
    16681 agaggtactg ttcatgtgac gcgccggacg ctgccagtcg agggcaaacg ccagcggctg
    16741 ccagccggtt tgcggacgca gtttttcctg acctacatag tgcgcccagc cgcccccgct
    16801 ctgaccgaca caaccgcaga aaatcagcat gttgatcaga ccacgatagt tcatgtccag
    16861 gtgataccag tggttcagcc ctgcgccgac gataatcatc gaacgaccgt gcgttttatc
    16921 agcgttatcg gcaaattcac gggcgatgcg aataatctgg ctgcgagaaa cgccggtaat
    16981 ctgctctgcc caggcagggg tgtaagcttt cacatcgtca tagctggttg cacagttaac
    17041 gtcgttcagg ccacgttcca gaccgtagtt tgccagcgtc agatcataaa cggtggtcac
    17101 cagggcggtg ctgccatcag ccagttgcag gcgtttcacc ggcagcttat gcagcagcac
    17161 gttttccagt tccactttgt tgaagtgttc cgtgccatcg ccaccaaagt acgggaagcc
    17221 cacctcagcg atctcatcct ggctacccag caggctcagt tgcagctcgg tttcttcgcc
    17281 agttttgccg tcgcgctgct caagattcca tttgcccttc tcgccccagc ggaagccaat
    17341 agaaccgttc ggcgcaacca tttcaccatt ggtattaaag gcgacagttt tccattccgg
    17401 attgttttcc tggcccagtg catccaccag atcagcagcg cgcagcatac gacccgcagc
    17461 gtagtaaccg tcgcgctctt ccagcatcac cagcatcggc atgtcggtgt agcggcgcac
    17521 atagtcggtg aaatactggc ttgggttgtc gaggtggaat tcacgcagca ttacgtgacc
    17581 cattgccagc gccattgccg catcggtgcc ctgtttcggt gccagccaca gatcgcacag
    17641 tttggcgatt tcagcgtagt ctggtgtgac ggcaacagtt ttggtccctt tgtaacgcac
    17701 ttcagtaaag aagtgagcat ccggggtacg cgtctgcggc acgtttgaac cccaggcgat
    17761 gatgtagctg gagttgtacc agtcagcaga ttccggtacg tcagtttgct caccccaggt
    17821 ttgcggagac gcaggaggca ggtcgcagta ccagtcgtag aagcttaagc aagtaccgcc
    17881 aatcagcgag agatagcgcg cacccgatgc gtaagaaacc atcgacattg ccggaattgg
    17941 cgagaagcca gcgacacggt ccgggccgta atttttgatg gtgtaaacgt tagatgcggc
    18001 gatcagttcg ttcacttcct gccaggaaga acgaacaaaa ccaccgcgtc cacgcgcctg
    18061 cttaaagctt ttcgctttat cggcgtcttc aatgatagaa gcccatgcct caaccggatc
    18121 gctatgcagc gccttcgctt cacgccacat tttcatcagg cgtttgcgca tcatcgggta
    18181 tttcaggcgg ttagcgctgt aaagatacca ggagtagctg gcaccgcgcg ggcagccgcg
    18241 aggttcatgg tttggcaggt ccgggcgagt acgcggatag tcagtctgct gggtttccca
    18301 ggtgaccaga ccgtttttga cgtagatttt ccagctgcag gagccggtgc agtttacccc
    18361 gtgggtagag cggacgattt tgtcatgctg ccaacgctgg cgatatccat cctcccagtc
    18421 acggttggta ttgagaagct ggccatgccc atcggcaaag gtttcaccct tctgtttgaa
    18481 gtagcgaaac cggtccagga atttactcat cggttttctc ctgtgggagc ctgtcggccc
    18541 tctgataaat cgacattgct aatgtttaag ggcaaggtaa cgctctgaaa cagcgtggga
    18601 attgataacg atcaagagtg atggggatga aaaataaagt aaattcctgg aatacccctt
    18661 taggataatt aacatttata gcataacaga ctgtaaatta agacgtttta cacctgtggt
    18721 tatttaaacc attaagattt ttatgcagat gggtattaag gagtattccc catgggtaac
    18781 atattaatga ctcttaatga aatccagcga aataagccat acaacattag tatgttgtaa
    18841 ctaaatgacg cataaaaaaa gcgcgacatc atgccgcgca aaggataatc aaatattacg
    18901 atttattttt tagaatgccg accatatacc gcccaggtaa tcaccacgca ggcgatatag
    18961 aaaatcaaaa atactttcat tgcgccgact ggcgaacccg ttaatgccag cgagctacca
    19021 aacgctttcg ggataaagaa gccaccaatc gcgccaatcg cagagatgaa acccagcgcc
    19081 gccgccgtgt cggttgccgc ttcacgcatc gcacgttcgt cagaaccccc ttctgctttc
    19141 acgcgatcca ttgtcagttt acggaagatc acggaaatca tctggaaagt ggaaccacta
    19201 cccagcccag cggtcaggaa cagcgcaagg aagactgcga agaacgccat gaagcttccg
    19261 ccctgtccgt cagtcggtaa ggtcaggaac agcaggccgc tgaaaatcgc catcaggata
    19321 aagttcacca gcgtgacacg agttccgccc agacggtcag ataatgcacc acctgcagaa
    19381 cgcgccagcg caccaataaa cggcccgaag aaagcgtatt gcagaatctg aacatccggg
    19441 aactgcgttt ttgacagcat cgcaaagccc gcggagaagc cgatgaagga gccgaaggtt
    19501 gccagataca gaaggctcat aatccacaga tgaccccgtt tgagtaccgg caactgctcc
    19561 ttgatggagg ctttcgaggt agcaagatcg ttcatgccaa accacgccgc aatggtgaag
    19621 atggcaagga acggcaccca tatccaggac gcattcgcca gatacagctc agtcccatcc
    19681 ggctgtttga cgccctggct accaaatact gcgaaaatcg acagtgatac caccagcgga
    19741 gcaaccaact gcatgacgct gacgcccatg ttgcccagac caccattcag acccagcgcg
    19801 ccaccctgct tctgtttcgg aaagaagaag ctgatgtttg ccatactgga tgcgaagttc
    19861 gcgccagcaa agccgcacag cagagaaatg atgatgaaga cgctataagg cgtggaggta
    19921 tcctgcacgg caaaacccag ccagacgcaa ggaataatca gaataccggt gctgaacgcc
    19981 gtccagcgac gaccaccaaa gataggaacc ataaaggagt atggaacacg taataacgcg
    20041 ccagaaaccg aaggcagcgc agtcaacata aatagctgat cggtcgtaaa attaaaaccg
    20101 actttcggta agttcaccgc aacagcgctg aacaacatcc atacgcaaaa cgccagcaac
    20161 agacagggaa cggaaatcca caggttgcgg ctggcaatac gttgaccgcg ttgttgccag
    20221 aacgcaggat cttccggtcg ccaatctgta atgacagctc cagtagccct ttcgggggcg
    20281 gatgagtgac tcatagacac ctctgatact cgtttcgatg tctgccacct tagtgtctgt
    20341 agctaaaggc aatttgatgt aaatcaaacg ataagataac tttatctatc attgatattt
    20401 atcattatcc atagtgagta cagtgatttc ataaaaatta tgagattttt cacggtactg
    20461 taaaatccct acccttaccg atgtaaagcg actaaccaca cggcaaataa ggagtaactc
    20521 tttccgggta tgggtatact tcagccaata gccgagaata ctgccattcc agaatgtatc
    20581 gtcacattca ttaaggttat tgctcattta aagcctgaag gaagaggttt acatgcttaa
    20641 acgttgtctc tctccgctca ccctggttaa tcaggttgcg cttattgtgt tgctttctac
    20701 tgctattgga ctggcaggga tggcggtttc tggctggctg gtgcaaggcg ttcagggcag
    20761 cgcccatgcg atcaacaaag cgggatcgct gcgcatgcaa agttaccgtc tgttggcagc
    20821 agtgccatta agcgagaaag acaagccctt aattaaagag atggaacaaa cagcatttag
    20881 cgccgagttg actcgagcag cagaacgaga cgggcaactg gcgcaattac agggtttaca
    20941 agattactgg cgtaatgaac tgatccctgc actgatacgt gcacaaaacc gcgaaacggt
    21001 gtcagcggat gtcagccagt ttgttgccgg gcttgatcag ctggtatctg gttttgatcg
    21061 caccacggaa atgcgcattg agacagtggt gctggtccat cgggtaatgg cggtatttat
    21121 ggcactttta ctggtattca ctattatctg gttgcgggcg agattgctac aaccgtggcg
    21181 gcaactgctg gcaatggcga gtgccgtcag ccatcgcgat tttacccaac gcgcaaacat
    21241 cagcgggcgc aacgaaatgg cgatgcttgg aactgcgttg aacaatatgt ctgcagaact
    21301 ggcggaaagt tatgccgtac ttgagcagcg ggttcaggag aaaaccgctg ggctggagca
    21361 taaaaatcag atcctctctt ttttatggca ggctaaccgc cgtttgcatt cccgcgcccc
    21421 gctgtgtgaa cgcctgtcac ctgtactcaa cggcttacag aatttaaccc tgctacgtga
    21481 tatcgaactg cgggtgtatg acactgatga tgaagagaat catcaggagt ttacctgcca
    21541 gtcagatatg acttgtgatg ataaaggctg ccagctctgc ccgcgcggcg tattacccgt
    21601 tggcgatcgc ggcacaaccc tgaagtggcg gctggctgac actcatacgc agtacggtat
    21661 tttgctggcg accctgccgc aggggcgtca tcttagccat gatcaacaac aactggtgga
    21721 taccctggtt gaacaactca ccgccacgct ggcgctggat cgccatcagg aacgtcagca
    21781 acagttgatc gtgatggaag agcgtgccac cattgcgcgc gaactgcatg attctattgc
    21841 ccaatctctc tcttgcatga agatgcaggt gagttgctta cagatgcagg gcgatgcgct
    21901 gccagaaagc agccgcgaac tgttaagtca gatccgtaac gaactgaatg catcctgggt
    21961 gcagttgcgt gaattgctca ccacattccg tttgcagctc accgagcctg gattacgtcc
    22021 ggcgctggag gcgagttgcg aagagtacag cgccaaattt ggcttcccgg tgaagctgga
    22081 ttatcaattg ccgcctcgtc tggtgccttc gcatcaggca atccacttgt tgcaaattgc
    22141 ccgtgaggca ttaagtaacg ccctcaaaca ttcgcaagcg agtgaggtcg tggtgacggt
    22201 ggcgcaaaac gataatcagg tcaaactgac cgtccaggat aacggctgcg gcgtgcctga
    22261 aaatgccatc cgcagcaatc actacggcat gataataatg cgcgaccgtg cgcaaagttt
    22321 acgaggcgat tgccgcgtcc gccgtcgtga atcaggtggc accgaagtgg tggtcacctt
    22381 tattcccgaa aaaactttca cagacgtcca aggagatacc catgagtaat caggaaccgg
    22441 ctactatcct gctgatcgac gatcacccga tgttgcgaac tggcgtaaaa cagcttatca
    22501 gtatggcacc agatatcact gtggttggcg aagcgagtaa tggcgaacag ggtattgaac
    22561 tggcggagtc tcttgatccc gatctgatcc tgttagatct caatatgccc ggcatgaacg
    22621 gtctggaaac gctggataaa ctgcgcgaaa agtccctctc cgggcgcatt gtggtattca
    22681 gcgtctctaa ccatgaagaa gatgtggtca ccgcactgaa acgcggcgcg gatggctatc
    22741 tgttaaaaga tatggaaccg gaagatctgc tgaaagcgtt acatcaggca gctgctggcg
    22801 aaatggtatt aagcgaagca ttaacgcctg ttctggccgc cagcttgcgc gctaaccgtg
    22861 ccactactga gcgcgatgtt aaccagttaa ccccacgcga gcgcgatatt ctcaagctga
    22921 ttgcccaggg tttgccgaac aagatgattg cccgccgcct ggacatcacc gaaagcacag
    22981 taaaagttca cgtcaagcac atgctgaaga aaatgaagct aaagtctcgc gtggaagctg
    23041 cggtatgggt gcatcaggag cgcattttct gattacggtt cccagcgcag ttcgtcgttt
    23101 gacaatgcgt cgaacggttc gacaagcgtt agcgtgatct cattggagga gacacgctgc
    23161 ccctggttat cttccaccac tacagacaat cgccagtgat tgctcgcccc ttccccgttc
    23221 tgccagtcag gcatgatcag cgtccagccc tcctcactgt tggcttgtgc gcccggcgtc
    23281 aaacttaata tctgcgtatc gccctgccaa atcagttgcc gaataccgta acgactgcgg
    23341 atttgtaatt tcagcggcac tgtttcgcca ggttttagat cccacggcgg tgtcgccaga
    23401 aacaccgtta acgtttttcg ctgtcggtac tcaagagtcg gaagattatt tcgctgcgga
    23461 ttgtcatagc gactaccacg taacgactga ctttcgacaa cctcgcccgc agaaagttgt
    23521 tttttgagcg gtacaccaaa gcggtagtta agattcagcc cgaggttatt ttgattctcg
    23581 ccactttcac cctgtttatg ctgggccgtc acagtgacta agggcacagg ggtgtaattt
    23641 aatcccagac tcaacgcgac gggattgtga taacccgtac cagagttaaa caaatcgaca
    23701 cgatcaccaa aatactgttc tacgctgaca ctggtattga ggtgttgata gaacggcatg
    23761 cgcatccggg ctgtcaggtc gtacccgcgc gccatccgtt gttcctgcgt ggcagtctgt
    23821 tcatgccatg cagcaaacgg ctgataaaag tttgccgata gtcgcaaata ttcgccccac
    23881 gcttcagcgc caaagcccgc tcgctgaaga ttttcgtcca gcaagttgtc ataaaaagtg
    23941 ttataaccca ccagccagct gccgcgcgcc cagcgttgcc caacgcccac attgctcacc
    24001 agcccatcat cctgctgagt aagaccaagc tggctccagg tgagataacg atcattatct
    24061 tgtaacggca caaaccagct tccacgactg ccggtgaaat gtccttcgtt atccactttg
    24121 acgtcaacac tggcatttcc ccacggtgat agccaggact ctacgtgctg attaacctgt
    24181 tgactaagcg catcgcggac ttttcccaat gcgaaagctt ttgcctgctc gccagtatcc
    24241 agcccgttat cattcatact ggtttcgccg aaatctttca caatttcagc aaagtgtttt
    24301 tccccatcat gatgttcagg tgccatgcct aaatccggca gaccatcatt gctattctca
    24361 aagtgatttg ccgctttttg ctcgaaggta gattgtgcgt tagctgtacc gcctgccgcc
    24421 agcaagagta aataaaacgg aataatgcga ggaacgaaac ggctcaaaac gtcggtaact
    24481 tccggtaaaa atgaaaaacc atagccttaa agaataacga ttactggcac cttttgtcgt
    24541 attttctcgc gctttcagga aaatccttaa aaatgtgacc gattggtcag acgctgcaga
    24601 agcagtaaga tagaagatga gtgtctaatt ccctgaatac aggagtaaat aatgcaaaaa
    24661 atcgtgatcg ttgccaatgg cgcaccttac gggagcgaat ccttgtttaa cagcttgcgg
    24721 ctggccattg cgttacgaga gcaggagaac aatctggatc tgcgtctgtt cctgatgtct
    24781 gatgcggtca cagccgggtt gcgcgggcaa aaaccagggg aaggctacaa cattcagcaa
    24841 atgctggaga tccttaccgc tcagaatgta ccggtgaaat tgtgcaaaac ctgtaccgac
    24901 gggcgcggga ttagtacact tcctctgatt gatggggtgg aaatcggtac tcttgttgaa
    24961 ctggcgcaat ggacgctgtc agccgataaa gtgctcacat tttaatgttt gagggggcgt
    25021 cggacgcccc actatgaggg aagtttactc aggcgaatcc cggccgtaac acaccatccg
    25081 gataattctc cgccagcagt ttttttaccg ataccagcaa atcattcagc ccatcgtcct
    25141 gcattcccag tttgataagc tcctgttcca gtgaaaacag gtattgtgca ttggttccca
    25201 gcggaccgct cgccgcggca atcaacggcg ctatgacctg agcgcgagtg tcagattcat
    25261 attctggatg tcgcgggtcc ataataaaca caatggcgtt tactgtgcgt ccatcatcaa
    25321 gatcaagctg acaccaggtt ggcagataac agccggtaat catctcacgc ttccacagca
    25381 gggttagttc ctgctccagc gtctcttctg gcagtcgata ggcgacgcct gtggtgcgtc
    25441 cgccctcttt cagtgcaagc attcgtcccg gctggtgcgc agtcccgcgc ccggcggtca
    25501 gacgcaggca aaacgcgcga tgccatccaa ccagtgtacc ggtgcacgac tcggtaaact
    25561 ccagtgccgg attccacatc aacgatccat aaccgaagat ccacaccggt ccctcatcag
    25621 gtcgacaagc cagcgtcgcc gccagcgaag ccgcccgttg ttctgctgac cataagagtg
    25681 attcttcaat ggcaccaaat gccgttttac aatcggcatt catcaagaaa tcacgcgtta
    25741 tcaccttaca cctccgccac tgcatacttc cctgcgacaa ctttttggtg tcttccggac
    25801 atttttactg ctcattttga aaccactaac gggacaatat gcaatccacg gaccacttgc
    25861 aaggcaacac cgcacgaata gctttaacta agctaccggt ttgacgattt tttatgccat
    25921 ttatcatcat cccctttggc atattcatgc ttcacagcag cccaggccac tttatgcgct
    25981 gtttcttcgc gactggcgtc atcacgccga tcttctttat ctttatattg atcccatgcg
    26041 ctgttgaacg cttctttata gatatcctgg gcatgagacg gaagcacgtg ctttacgctt
    26101 tccggcagat cgcttttcgt tttatacgac atcgttgact ccttttacaa agttgaacat
    26161 taagtgtggt caacaatatc tactcttgcc aaaacataag aattttcatg tcagactctt
    26221 cttaagaagt gctaaaacaa acattgtcta aacgtat
//
LOCUS       DAPOXO010000074        25815 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPOXO010000074 DAPOXO010000000
VERSION     DAPOXO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25815
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.074"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            241..1539
                     /gene="kgtP"
                     /locus_tag="ROH59_003631"
     CDS             241..1539
                     /gene="kgtP"
                     /locus_tag="ROH59_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HDX4806068.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAVLREWGWRIPFALGAVLAVVALRLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPIIGALSDKIGRRTSMLCFGSLATIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAFANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLTLHRKGKGMRL"
     gene            complement(1536..1859)
                     /locus_tag="ROH59_003632"
     CDS             complement(1536..1859)
                     /locus_tag="ROH59_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HDX4806069.1"
                     /translation="MRILFVCSLLLLSGCSHMANDNWSGQDKAQHFIASAMLSAAGNE
                     YSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDFAWDIAGASTGYTVW
                     QLTRH"
     gene            complement(1905..3260)
                     /gene="pssA"
                     /locus_tag="ROH59_003633"
     CDS             complement(1905..3260)
                     /gene="pssA"
                     /locus_tag="ROH59_003633"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HDX4806070.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVNVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWILITGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELDLIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            complement(3374..6034)
                     /gene="pat"
                     /locus_tag="ROH59_003634"
     CDS             complement(3374..6034)
                     /gene="pat"
                     /locus_tag="ROH59_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HDX4806071.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIANLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPGHV
                     AISNPLDLRDDASSEHYVKTLDILLHSQDFDALMVIHSPSAAAPATESAQVLIEAVKH
                     HPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RVHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDIAPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLSLAQREES"
     gene            complement(6066..6764)
                     /gene="tapT"
                     /locus_tag="ROH59_003635"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             complement(6066..6764)
                     /gene="tapT"
                     /locus_tag="ROH59_003635"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HDX4806072.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSHFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLDLVQNP
                     DYQPMVVFPASYADEQREVIFTPPADKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTRAATGLGEHFTRFKTRYLAGKT
                     QHPGSITAEQLESV"
     gene            complement(6833..7252)
                     /gene="trxC"
                     /locus_tag="ROH59_003636"
     CDS             complement(6833..7252)
                     /gene="trxC"
                     /locus_tag="ROH59_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HDX4806073.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            7459..8496
                     /locus_tag="ROH59_003637"
     CDS             7459..8496
                     /locus_tag="ROH59_003637"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDX4806074.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSQHRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            complement(8544..9233)
                     /gene="ung"
                     /locus_tag="ROH59_003638"
     CDS             complement(8544..9233)
                     /gene="ung"
                     /locus_tag="ROH59_003638"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDX4806075.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPI
                     DWMPVLPAESE"
     gene            9538..9921
                     /gene="grcA"
                     /locus_tag="ROH59_003639"
     CDS             9538..9921
                     /gene="grcA"
                     /locus_tag="ROH59_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HDX4806076.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            complement(9977..10564)
                     /gene="eamB"
                     /locus_tag="ROH59_003640"
     CDS             complement(9977..10564)
                     /gene="eamB"
                     /locus_tag="ROH59_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HDX4806077.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLA
                     GMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRQLNIVLALLLVYCAVRIFY"
     gene            10667..11548
                     /locus_tag="ROH59_003641"
     CDS             10667..11548
                     /locus_tag="ROH59_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417072.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4806078.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVISGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDDALNRRELG
                     EQPLVLVASPQIADVDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     ISIESIKRCVAANIGVSYLPRFAVVKELECGELIELPFGEQSQTITAMCAHHAGKAVS
                     PAMHTFIQCVEECFLPG"
     gene            complement(11581..12915)
                     /gene="srmB"
                     /locus_tag="ROH59_003642"
     CDS             complement(11581..12915)
                     /gene="srmB"
                     /locus_tag="ROH59_003642"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HDX4806079.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
     gene            13047..13784
                     /gene="trmN"
                     /locus_tag="ROH59_003643"
     CDS             13047..13784
                     /gene="trmN"
                     /locus_tag="ROH59_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HDX4806080.1"
                     /translation="MSQSTSVFRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADILQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            complement(13769..15391)
                     /gene="nadB"
                     /locus_tag="ROH59_003644"
     CDS             complement(13769..15391)
                     /gene="nadB"
                     /locus_tag="ROH59_003644"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDX4806081.1"
                     /translation="MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVGKAQNHPNIRVLERS
                     NAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTKEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDISRRIPYAHGVSTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSAGNHYINR"
     gene            15647..15802
                     /gene="rseD"
                     /locus_tag="ROH59_003645"
     CDS             15647..15802
                     /gene="rseD"
                     /locus_tag="ROH59_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HDX4806082.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            15799..16374
                     /gene="rpoE"
                     /locus_tag="ROH59_003646"
     CDS             15799..16374
                     /gene="rpoE"
                     /locus_tag="ROH59_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HDX4806083.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            16407..17057
                     /gene="rseA"
                     /locus_tag="ROH59_003647"
     CDS             16407..17057
                     /gene="rseA"
                     /locus_tag="ROH59_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HDX4806084.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            17057..18013
                     /gene="rseB"
                     /locus_tag="ROH59_003648"
     CDS             17057..18013
                     /gene="rseB"
                     /locus_tag="ROH59_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HDX4806085.1"
                     /translation="MKQLWFAMSLVTGSLLFSANALATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDIGSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGTAQ"
     gene            18010..18489
                     /gene="rseC"
                     /locus_tag="ROH59_003649"
     CDS             18010..18489
                     /gene="rseC"
                     /locus_tag="ROH59_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HDX4806086.1"
                     /translation="MIKEWATVVSWENGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFAS
                     DVAALCGAILGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            18687..20486
                     /gene="lepA"
                     /locus_tag="ROH59_003650"
     CDS             18687..20486
                     /gene="lepA"
                     /locus_tag="ROH59_003650"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDX4806087.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTGQTYNADRLGIFTPKQIDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRGNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            20502..21476
                     /gene="lepB"
                     /locus_tag="ROH59_003651"
     CDS             20502..21476
                     /gene="lepB"
                     /locus_tag="ROH59_003651"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDX4806088.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            21748..22428
                     /gene="rnc"
                     /locus_tag="ROH59_003652"
     CDS             21748..22428
                     /gene="rnc"
                     /locus_tag="ROH59_003652"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDX4806089.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            22425..23330
                     /gene="era"
                     /locus_tag="ROH59_003653"
     CDS             22425..23330
                     /gene="era"
                     /locus_tag="ROH59_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDX4806090.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            23342..24070
                     /gene="recO"
                     /locus_tag="ROH59_003654"
     CDS             23342..24070
                     /gene="recO"
                     /locus_tag="ROH59_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDX4806091.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            24082..24813
                     /gene="pdxJ"
                     /locus_tag="ROH59_003655"
     CDS             24082..24813
                     /gene="pdxJ"
                     /locus_tag="ROH59_003655"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HDX4806092.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVCILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQREKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAATFATSLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            24813..25193
                     /locus_tag="ROH59_003656"
     CDS             24813..25193
                     /locus_tag="ROH59_003656"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDX4806093.1"
                     /translation="MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWEIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVVNMHVTLADERHYACATVIIES"
     gene            25614..25694
                     /gene="shoB"
                     /locus_tag="ROH59_003657"
     CDS             25614..25694
                     /gene="shoB"
                     /locus_tag="ROH59_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HDX4806094.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLLLLFL"
BASE COUNT         6362 a         6401 c         6784 g         6268 t
ORIGIN      
        1 ttatactccc acataagcca gattcaacag cgaatacgtc ttccccaaat tgcccacttc
       61 catacttcct ccttaccaga aatctatcct taagctcctt aataaccatt ttcctgctaa
      121 ctaaattcat ggttaaggtt gtataatgat gcgcaacaaa tgtataacat tttctttacc
      181 aaaaaaaata aacaaaagcg accgacaaaa gcatcggatt acggcaggag acataatggc
      241 atggctgaaa gtactgtaac ggcagacagc aaactgacaa gtagtgatac tcgtcgccgc
      301 atttgggcaa ttgttggggc ctcttcaggt aatctggtcg agtggttcga tttctatgtc
      361 tactcgttct gttcactcta cttcgcccac atcttcttcc cttccgggaa cacgacgact
      421 caactactgc aaacagcagg tgtttttgct gcaggatttc tgatgcgccc aataggcggt
      481 tggctgtttg gccgcatagc cgataaacat ggtcgcaaaa aatcgatgct gttatcggtg
      541 tgtatgatgt gtttcggctc actggttatc gcctgtttgc caggctacga aacaatcggt
      601 acctgggctc cggcattatt gcttctcgcg cgtttattcc agggattatc cgttggcgga
      661 gaatatggca ccagcgccac ctatatgagt gaagttgccg ttgaagggcg caaaggtttt
      721 tacgcatcat ttcagtatgt gacgttgatc ggcgggcaac tgctagctct actggttgtc
      781 gtggttttac aacacaccat ggaagacgct gtactcagag agtggggatg gcgtattcct
      841 ttcgcgttag gagctgtgtt agctgttgtg gcgttgcggt tacgtcgtca gttagatgaa
      901 acttcacaac aagaaacacg cgctttaaaa gaagctggat ctctgaaagg attatggcgc
      961 aatcgccgtg cattcatcat ggttctcggt tttaccgctg cgggctccct ttgtttctat
     1021 accttcacca cttatatgca gaagtatctg gtaaatactg cgggaatgca tgccaacgtg
     1081 gcgagtggca ttatgactgc cgcattgttt gtattcatgc ttattcaacc aattattggc
     1141 gcgctgtcgg ataagattgg tcgccgtacc tcaatgttat gtttcggttc tctggcaacc
     1201 atttttaccg ttcctattct ctcagcattg cagaacgttt cctcgcctta tgccgctttt
     1261 ggtctggtga tgtgcgccct gctgatagtg agtttttata cttcaatcag tggaatactg
     1321 aaggctgaga tgttcccggc acaggttcgc gcattaggcg ttggtctgtc atatgcgttc
     1381 gccaatgcta tatttggtgg gtcggcggag tacgtagcgt tgtcgctgaa atcaatagga
     1441 atggaaacag ccttcttctg gtatgtgacc ttgatggccg tggtggcgtt tctggtttca
     1501 ctaacattgc accgtaaagg aaaagggatg cggctttagt gacgggtcag ttgccagacg
     1561 gtatagccgg tgcttgcacc ggcgatatcc caggcaaaat ccttccagct ccagccgctc
     1621 ccctcagggc ggctatccca aagctctttt gacgccccca gactgacaga gaacatcaat
     1681 ccaaacatgg cactgcgatc ccggctcatc ccctgatgct gtgaatattc atttccggcg
     1741 gcggaaagca tcgccgaggc gataaagtgt tgagctttat cctgcccgct ccagttatcg
     1801 ttagccatat ggctgcatcc agaaagtaac aatagcgaac agacaaaaag aatacgcaaa
     1861 acgtggcctc caaaaaacaa accccgtaca ggacggggtt gtgattacag gatgcggcta
     1921 attaatcggt cgatgcggat acggcgcaaa cggcggatga gtttacgaac cttcaccgga
     1981 taatcggcaa tactttgcag atcgcggtag tgcttaacga tggtggtatg ctcgcggatc
     2041 agatccagtt ctttctctcg ctgtggcgca agctccagtt gcggatcgtg gatcaaaatg
     2101 gcgttttcca gatccagacg ccaggcgcgc gggttcaggt tattaccggt gatcaaaatc
     2161 cacttatcat caacccacat ccctttcagg tgataggtgt tgtcgtcatc tttccataac
     2221 cgaactacta actggtcagt gttgacgtaa tactgtaaac gactcaggaa acgacgcaga
     2281 ttgatctcat agagataagg caatgcgcca attatcttga aaggttcatc ttccggaatg
     2341 tagaagtcat tcgcggtttt atcaccaaca ataatttcga cctttttccc ttcgcgcagc
     2401 aactggataa tattgcgcac aaggattgct ggtaggttga agtaaggtgt gcagatggtt
     2461 agtttctgct cggcacaagg cataagatgg aaaatagtct tgttcaacag actcgatttc
     2521 cccagcccca ctagcggcgt tacggaaagc tgatcgttgt cggcatcgcc ctggaaatga
     2581 taagcggcat cacgcagctc ctggcggaac aggcgaatgt cgttcttgat ttccgggctt
     2641 tttggccgat taacatcatc cagacgatta acgccgcggc cattcataat attctgtgta
     2701 acccattcaa acataatgtc tgacatctta cggttacgga tcagatgata acggtcgtag
     2761 cgatatttat cgtgctgatg caggtaaaca tcgttcaggc tggcaccgct ataaagtacg
     2821 ctatcgtcga tgataaagcc tttaaagtgc agaacaccaa gggcttcacg ggtattgatt
     2881 ggaacgccat aaaccggaac atttacgccc ggattttcct gcgccatgcg gcagtaccag
     2941 tcagcgttag tgttagatgc cgcagcgcca atgcgtccac gttgtgcacg atgccagtcg
     3001 accagcaccc gcacatccag ttccggacgc tgccttttag cctcatacaa cgcgttcaga
     3061 atgcctttgc caccgtcatc ctgttcgaga tacagggcaa caatgcaaat gcgctgcttc
     3121 gcgctggcta ttttttccag caacgtctcc cggaagtcgg cgggagcgta aaagaaatcg
     3181 acatcatcaa ctgattgaga aatcttgggt agttgggcaa ggtgttgttg atgtttatta
     3241 cgcttaaatt ttgacaacat cacagtgcat ttcttctctg ttcattgaag ggtcctctgt
     3301 gcaatgcaga cgacataagc gggcaataat aacaccagtc ccgattaagt ggtcaacatt
     3361 tccagtacct tactcatgat tcctcgcgct gggcaagact tagcgtaagc ccaacgatcc
     3421 cctcttcgag ctggatatca acgttaaacc cgagcttgcg ggccagcgcc accatgccac
     3481 gattgtttgg catcgtaata ccattcagac gttgtagtcc gtgatctcgc gtataggtaa
     3541 tcaacttttc cattaagcgt cgacctaagc ctaacccttt aagatccgag cgaaccagta
     3601 cggcaaattc ggcatcgatg ttatcagggt cggagatcgc acgtgtgacg ccgaggatct
     3661 cttccgtttg atcaattcgt cgtaccgcta caaatgccat ttcccgatcg tagtcgatct
     3721 gcgtcatgtt ggctaaatct tcatgggtaa attcgttgat ctcgctaaag tagcggtaat
     3781 aaagatcttc tttggtgact cgcgaaatga attgctgaag ctgtggctca tcttctggca
     3841 aaatcgggcg gaacaagcag cgttcaccgt ttttcaattc tacccattct tccagctgat
     3901 gcggataagg gcgcacagcc agtcggctct cgttatcacc ttcaaacggc gcgatatcca
     3961 gcgtgacatc cagcgcggta aattcactgc cagaagccag caaaggatga atatccagac
     4021 gctgaatttc cgggcaatcg acaatcaagt tggaaacctg caccagaagc tggctcaagc
     4081 ctgcaacatc caatgggcgt agcgcactgc gcgcacgaat ctttttactt ttgatcccct
     4141 gaataaccag atagcgggcc aggttcatgt tcagcggcgg cagtgcgacg acggcttgat
     4201 cttcaggacg ccactccaca ccgccttcac ccagcatgat caacggcccg aaaaccggat
     4261 cgtgctcaac cacaacccgc aactcctgag cgccagcacg gttagccata ctttgcacca
     4321 acaggccgtg gacccgcgcc tgcggccagg ccatttttac gcgatcgaaa atagcgtttg
     4381 ccgcttgctg gacttcattg gctgtacgta ggtagagcat gacgccctga acttccgatt
     4441 tatgtggaat atccggcgag cgcaatttca gtgccaccgg atagccaatc tgttcggcaa
     4501 tatgtaccgc ttcggtgcta tcactggcaa tccaggtagg gagagtattc ataccatacg
     4561 cttgcaggat gggctgaact tcatgggtat cgagcgacgt agccccttcg gcaatcgcct
     4621 gttgcaacag aagatgcgct tctgcggtat tggaagtcag attgctgggc aacgccggcg
     4681 tttcgcgtag ttgcttctga ttacgccggt actcgaccat atgcataaaa gcagtgatgg
     4741 ttccttccgg agtacggtag gtcggcagcc cggcttcgct gaataaacgt cgtgcctctt
     4801 gcgaggagtg ctcgccgcac cagttcgtca gcaaagagac atatttgctg cggggatgat
     4861 gctttaccgc ttcaattaat acttgcgcgc tttctgttgc gggagcagcg gcgctgggcg
     4921 aatgaataac catcagcgca tcaaaatcct ggctgtggag cagaatgtcc agcgttttga
     4981 cataatgctc gctgctggcg tcatcgcgca gatcgagcgg gttagagatt gccacatgcc
     5041 ctggcagtgc atcgcgcagt ttctggcagg tttcttcgct tagcgttgcc agcttgccat
     5101 tgcgtgacca taaggcatcc agcgccagcg cggcaggcgc agcaccgttg ctgataatca
     5161 tcaaccggtc gccacgcagc gggcgcatat ggctaagggt ttccaccgcc gaaaacagtt
     5221 cgtgggtgtc ctgtacccgc aacaaaccgg cacgctgaat agctgcatcc cacgccggat
     5281 ccattcctgc cgtggtgttc aacagacgtt gagccgccgg gctacgtccg cttttaatca
     5341 ccaaaatcgg tttattgcgc gaggcactac gggctgccga aacaaagcgt cgcgcgtcgc
     5401 ttaactgttc gagatagagc aggatggcgc tggttttact gtcgcgcgcc agatagtcga
     5461 gcaattcatc aacgtcgata tccaggctgt cgccgagcgc aataaagtag gaaaagccca
     5521 tctcacgctg ttgcgcccag tcgaggatgg tgttggagac agcagccgat tgcgaaataa
     5581 acgccagctt gccgcgttta atcggcacag gcgaaaagct ggcattcaga ccttgccagg
     5641 gagccagtaa gcccagactg tttggtccta gcaggcgcat gttatggcgc agggcgcagg
     5701 cgcggagatc ttcgtgttgc gatgccgggg cggaaagaat aatgcaggtt ttacagcctt
     5761 tctcgccgag ctcttccaga agagcaagat tacggctggc attggtacat aaaaccgcaa
     5821 ggtcgggtgt aaagggcaag ttggcaatat ccggccaggc caacacaccc aacaccgctt
     5881 tccaggctgg cgtcaccggg agtaccggtc cgttaaagcc tcccgccagc aggttacgca
     5941 tcatcaggta acctgcgcga ttgggtttca tcgatgcgcc aattaccgca atcgattttg
     6001 gtcgcagtag tgcttccagt cctcgctgac tcataccggt ctcccgcaga agtgaccgaa
     6061 tgattttaaa cgctttctaa ctgttctgct gtgatgcttc ccggatgttg cgtttttcct
     6121 gccagatagc gtgttttaaa gcgggtaaaa tgctcgccta accctgtcgc cgccctggta
     6181 tcgccggcca tatctaacag tgcgatggct acctcggcag tacaatattg gccttcagcc
     6241 tgggcttcac gcaggcgata ggcagaaagc cgagaaagat cgacggaaat gacgggaaga
     6301 ttatccagat acggactttt acgaaacatc ttgcgagctt ctggccaggt accatcgagc
     6361 atgataaata gcggaggctt atcggcaggt ggtgtgaaga tcacttcccg ttgctcatca
     6421 gcatacgaag cgggaaagac caccattggc tgatagtctg ggttttgcac cagatccagc
     6481 aaatcttgcg agggttcggt acgcgaccat tgaaacgcaa cggtatcagg caaaatatca
     6541 gcaatcagac gcccggtatt actgggcttc attggctcgg tgtcgaacat cagcaaacag
     6601 aagtgacttt ttgcttgtgc tggggtaatt gtcgaacaga gacataattt ctctggcaaa
     6661 agacagcgtt ggcagcgacg aacgcgatta ccgcgggcaa gaaaaggacg tgttgcgcgc
     6721 gcaatacgct cggcgcgtaa ctggagaaca gcgttttcgg tcataagaga gcgtcgaaaa
     6781 aacgccattg tcgcagagga gaaaacgggg cacaagatgc gccccggtaa gattaaagag
     6841 attcgttcag ccagctgtcg aacggcgctt tcggtactgc gccattaagc atgtcgacaa
     6901 cctgaccgtt tttgaaaatc atgatcgtcg gtatactacg aattccaaag cgactgctca
     6961 attcacgttc agcttcggta ttcactttca caaagcgcac tttaccgcta cgctcttgcg
     7021 cgacatcttc aaaaattggt gcgaaattac ggcaggggcc gcaccacggt gcccagaagt
     7081 cgatcaccac aggtagatca tctttcagca atttgtcgag cgtttcaccg gtcgcattaa
     7141 tcacctctcc gtcaaacaag tcgtgaccgc agcgtccgca ttttgccgca tcttcgatcc
     7201 gatcgtcggg aatgcgattg atggcctgac aatgggtaca aacggtattc ataactaacc
     7261 tcgggatgag taaggagact tatcggcaac gacgccggta tgtttctaat atgttacata
     7321 ttatcgggga cattgttcca gacaacaatc tgttttattc aatgggtatg atagacacag
     7381 gctttggaac gaaatcatgg cgaaccgcgc gcacttcggg taatctgcgc gcttcgcgca
     7441 gcgctggtgg agaaaagcat gaacgatgaa atgaaaggta aaagcggcaa ggtcaaagtg
     7501 atgtatgtcc gcagtgatga tgattctgat aaacgtaccc acaacccgcg taccgggaaa
     7561 gggggcgggc gtccaggaaa atctcgtgct gacggtggcc gtcgccccgc ccgcgatgac
     7621 aaacagagtc agcaccgtga ccgcaagtgg gaagattcgc cgtggcgcac ggtttcccgc
     7681 gcgccgggtg atgagacgcc ggaaaaggcc gatcacggtg gcatcagtgg taaaagtttt
     7741 attgatccgg aagttttgcg tcgtcagcgt gcggaagaaa cccgcgtcta cggcgaaaac
     7801 gcctgtcagg cactgttcca gagccgtccg gaagcgattg ttcgcgcctg gtttatccag
     7861 agcgtaacgc cacgttttaa agaagccttg cgctggatgg cggcaaaccg caaagcgtac
     7921 catgtggtgg atgaagcgga actgacaaaa gcgtcaggca cggaacatca cggcggcgtt
     7981 tgcttcctga tcaaaaagcg taacggtaca accgtgcagc agtgggtaag ccaggcaggc
     8041 gcgcaggatt gtgtactggc cctggaaaac gaatctaacc cgcataacct gggtggcatg
     8101 atgcgtagct gtgcgcactt cggcgtgaaa ggtgttgtgg tgcaggatgc agcactgctg
     8161 gagtctgggg cggctatccg taccgcagaa ggcggcgcag agcacgttca gccgattact
     8221 ggcgacaaca ttgttaacgt gctggatgat ttccgtcagg cgggttacac cgtagtgaca
     8281 acttccagcg agcagggtaa accgctgttc aaaaccagtc tgccagcgaa aatggtactg
     8341 gtgctgggtc aggaatatga agggttaccg gatgccgcac gcgatccgaa cgatctgcgc
     8401 gtgaagattg atggtactgg caacgttgcc gggctgaata tctctgtcgc aaccggcgtt
     8461 cttcttggcg aatggtggcg tcagaataaa gcctgataaa tcagccgggt ggcaactctg
     8521 ccatccggca ttttcccgca aatttactca ctctctgccg gtaatactgg catccagtca
     8581 atcggcgtct cgccacgttg ttccagccac tgatttgcca gcacaaaatg gttgcagcca
     8641 aagaatccac gatgcgccga aagcggcgac ggatgcggtg ctttcagtac atgatggcgt
     8701 tgcttatcta taatcgcccc tttcttttgc gcatgtgatc cccacaacaa aaacaccacg
     8761 ccttcgcgat gctgatttat gaggctgatg actttatcag taaacgtctc ccagccgagg
     8821 ctggcgtggg aatgcgcctg accagcgcga accgtcaaga cggtattgag cagcagaaca
     8881 ccctgacgcg cccagctttc aagataacca tgattagggc gggtgaaacc gggaatagta
     8941 ttttccagct ctttatacat attcagcagt gacggtggtg tcgcaatgcc ggggcgaacg
     9001 gaaaatgcca gaccatgcgc ctgtcctggt ccgtgataag gatcctgacc gagaatcacc
     9061 actttaacgt cacccaactc cgtaaagcgg aacgcgttaa agacatcttt ttgtggtgga
     9121 tagatagtga cgccggactg ccgctcgctg gcgacggtct gaagggtatt aagaaaatag
     9181 ggttgctgct tctcttcagc cagcacatca tgccaggtta attcgttagc catctcgctc
     9241 tcctgcgaat ctttaatccg cctagcttaa ctgcttcttt ctacagaaca aaatcatgct
     9301 cattttatag acaaaaagac atgcaaaaaa atgtaaattg gtaaaatttc acatctgcat
     9361 aagttgatgt aaaacaataa aatccatttg tgaccacact tgatatgtgg tttttattga
     9421 tttaaatcaa agaatcaagg gtgtttgagg agtatatata cactcaagca acaatggttt
     9481 taccaattgg ccgcgacagg ctgaacaaat caaataattt tgccggggag gcatcacatg
     9541 attacaggta tccagattac taaagccgct aacgacgatc tgctgaactc tttctggttg
     9601 ctggacagcg aaaaaggcga agcgcgttgc atcgttgcga aagcaggttt tgcagaagac
     9661 gaagtggttg cagtaagcaa actgggtgac attgaatacc gtgaagttcc agtagaagtg
     9721 aaaccagaag ttcgcgttga aggtggtcaa cacctgaacg ttaacgttct gcgtcgtgaa
     9781 actctggaag atgcagttaa gcatccggaa aaatatccgc agctgaccat ccgtgtatcc
     9841 ggttatgcag ttcgctttaa ctctctgact ccggaacagc agcgcgacgt tatcgctcgt
     9901 acctttactg aaagcctgta aggcttaagt agcaagttac taagcggaag agggcgacct
     9961 cttccgcttt ttttcgttaa tagaaaatgc gtaccgcgca atagaccagc aacagggcaa
    10021 gcacgatatt taactggcga ccatactggc gaaacaatcg ctgaaacaga tgccccgcca
    10081 gcgcccagca cacattgcca aacgtcccaa tcatcgccag caaaacgctg acgccaacta
    10141 cccagcttag cgcctgtgtt tgcggcagaa caaacgtcga cagtgccgta acaccgtaca
    10201 aaatgatttt gacgttcaca aactgcaaag caaagctggc ccaaaagctg attggttttg
    10261 cctgaagtcc gtcttccttt gttgggctgg tggcgatttt ccacgccagc cagacaatat
    10321 atgccgcccc cgcccaactc aaaaggtgta ccgctgccgg gtcaatcact gccagtgaaa
    10381 atgaaatgcc cgcacacagt aacatcacaa tcaaaaatcc cagactcatc cctgccagca
    10441 cacgggtact ttgacgaaat ccatgcgacg tagcagagct aagggcgaga atattgttcg
    10501 gtcctggcgt catggcggta atcagggtgt aagtccaaaa agcacttaaa agggtcggtg
    10561 tcacttgtta tctcctctgt tttggtagac agtacccgac acggaacatt taaaaaaatg
    10621 aatgttttta cattctaaat tcgatatttt cgataggttt ggggttatgg atctgcgccg
    10681 ttttattacg cttaaaaccg tggtggaaga gggttccttt ttgcgagctt cgcaaaaatt
    10741 gtgctgtaca caatcgacgg tgacttttca tattcagcag cttgagcagg agttctcggt
    10801 acaattgttt gagaaaattg gtcgacgaat gtgccttacc cgcgaaggaa aaaagctgct
    10861 gccgcacatc tatgaactta cccgagtgat ggatacgctt cgtgaggctg ctaaaaaaga
    10921 gtcggatccg gacggggaac tacgcgttat ttcaggcgaa acgttgctct cttatcgaat
    10981 gccgcaggtg ttgcagcgtt ttcggcaacg cgctccaaaa gtgcgtttat cgttgcagtc
    11041 gctgaactgt tacgtgatcc gtgatgcgct actgaatgat gaggccgatg tcggggtttt
    11101 ttatcgcgta gggaatgatg atgctctgaa ccgacgagag ttgggtgaac aaccgctggt
    11161 gctggtggct tcaccgcaaa ttgcagatgt cgattttact gagccgggaa gacataacgc
    11221 ctgtagcttt attatcaacg aaccacaatg tgtcttccgg cagatatttg agagcacgct
    11281 gcgccagcgg cggatcacgg tggaaaacac cattgagctt ataagtatcg aaagcatcaa
    11341 gcgttgtgtc gcggcaaata tcggagtcag ttacctgccg cgttttgcgg tagtaaaaga
    11401 gttggagtgc ggagaattaa ttgaattgcc ttttggcgaa cagtcgcaga ccattacggc
    11461 aatgtgcgct caccatgccg gaaaagcggt tagcccggcg atgcacactt ttattcagtg
    11521 tgttgaagag tgttttttgc cgggataaaa acaatgccgg gcttaaaccc ggcattgaga
    11581 ttactcttct gtcgtttgcg gtggcacgcc cgttccgctt ggtttacggc gcttaccaat
    11641 atttttagtg tcgcgatggc gttttttcac ccgcggcttc tctttctctt tagctttttt
    11701 cttctcggca cgtttagcca acactttctt cgatggcttg ccggtctgct tctcgcttgg
    11761 cgcacgcgtt ttcggacgta actcatcaat tacgcgagct ttaattggct cttcaatata
    11821 acggccaact ttgcccagca gcagatggtc atgggcttcc accagcgaaa tcgcggtgcc
    11881 tttacgaccg gcgcgcgcgg tacgtccgat acggtgcaaa taagtatcgc cactgcgcgg
    11941 catatcgaag ttaaagacgt ggctgacgtc aggaatgtcg ataccgcgcg cggcaacatc
    12001 ggtagcaacc agtacgttta cgcggccttc ggtcaagcgt ttaatcgctt cgttacgctt
    12061 gccttgtacc atctcacctt cgagatagca gttgttgatg cctgcttcgc gcagccagtt
    12121 tgccagctca tgcacacgct cacgcttacg cacaaacaca attgagcggg tcgcttccgg
    12181 ctgttttaac agatgcacca gcaacgcggt tttatgctca agatcatcgg cgcggtaata
    12241 ccactgatga atttttttgc gctcacgggt ggacggattg gcagaaactt ccaccggatc
    12301 ttccaacaga cgctcggcaa agtcctgaat cgcatcgcct tccagcgttg ccgaaaagag
    12361 cagggtctgt ttacgccagc gcgtttcgcc agcaatatgt tcgatatcct gggcgaagcc
    12421 catatccagc atacggtctg cttcgtcgag gatcagcgtt tcaaccgcgc ggcaatcgaa
    12481 gttctcttct tttatgtatt gcagcagacg tccggtcgtg gcgaccacaa tgtcctggtt
    12541 ttcgctgaac acttctgcgt ggttcatata ggccacgccg ccggtgatgg tggcaatatc
    12601 cagatgcgta tgtttcgcca gttcgcgggc atgatcggcc acctgcatcg ccagctcgcg
    12661 agttggggtg aggatcaaaa tacgcggcgg accggatttc ttacgtggga aatcgagcag
    12721 gtgctgcaac gctggcagca gatacgccgc cgttttaccg gtgcctgtcg gcgcagaacc
    12781 gagtacatca cggccatcga gcgcaggcgg aatggcggca gcctgaatgg cggtcgggcg
    12841 agtgaaacct ttatcctgga gggcttccag caggctttcg tcgagttcaa gttcggaaaa
    12901 agtcgttaca gtcatgttct acctctgtgt ggggcgctga ttatagacgt tacggctgca
    12961 atcttcatct gtttgtatgg atatcgcttc tcgggtattg ttctcacccg gtgctatcgc
    13021 cgtttttcct gcaaggtttt attttcatgt cacagtctac atccgtgttt cgtcgtaatg
    13081 gatttacttt taaacagttt tttgttgctc acgatcgctg tgcgatgaaa gtgggaacgg
    13141 atggcatttt gctgggcgca tgggcaccgg tagctggggt aaaacgttgc cttgatatcg
    13201 gcgcgggtag cgggttgctg gcattaatgc tggcgcagcg aacagatgac agcgtgatga
    13261 ttgatgcagt tgaactggaa agtgaagctg ccgcgcaagc gcaggaaaat atcaaccagt
    13321 ccccgtgggc agagcggatt aatgtccata cggcggatat tctgcagtgg atcacacagc
    13381 agacagtacg cttcgattta atcatcagca acccacctta ctatcagcag ggagtagagt
    13441 gcgcgacacc tcaacgggaa caggctcgct ataccactac gcttgatcac ccatcgttgc
    13501 tgacttgtgc ggcggagtgc attaccgaag agggattttt ctgcgtggtg ctgccagagc
    13561 agattggtaa tggttttact gaactggcat taagtatggg ctggcattta cgtttgcgga
    13621 cggatgtggc ggaaaacgaa gcgcgactgc cgcatcgggt gctgctggca ttctccccgc
    13681 aggcgggaga gtgctttagc gatcgcttag tcattcgtgg gccagaccag aactattccg
    13741 aagcgtatac ggcgctgacc caggcttttt atctgtttat gtaatgattg ccggcagaaa
    13801 ggatcgatgg accggaatgc gtgagcagtt ccggataatc cagcgtgaaa tgcaggccac
    13861 ggctctcctt gcgcatcatc gcacagcgaa caatcaactc ggcaacctgt accagattac
    13921 gcagctccag caaattattt gagacgcgga aatgggcgta atattcgtct atttcttgtt
    13981 ggagcatggt tatccgccgc agggcgcgtt ccaggcgctt cgttgtgcga acaatgccaa
    14041 cgtaatccca cataaacaga cgtagctcgt gccagttatg ctgaattact acccgttcgt
    14101 cagggttctc aacgcggctt tcatcccacg gcggtaacgt actgacgccg tgggcataag
    14161 gtatacgtct gctgatatct tctgccgccg accagccata gaccagacac tccagcaatg
    14221 aattcgaggc catgcggtta gcgccgtgta agccggtata actcacttcg ccaatggcat
    14281 acaaaccctc gacgtccgta cgcccatgat catcaaccat tacaccaccg caggtataat
    14341 gtgcagcagg cacaatcggc acgggttctt tcgtgagatc tatccccagc ccgagcaatt
    14401 tttcataaat catcgggaaa tgctggcgaa taaaatcggc gggcttatgg ctgatgtcga
    14461 ggaacataca atctgcgccg aggcgtttca tttcatggtc aatggcgcgg gcgacaatat
    14521 cgcgcggggc cagttcgccg cgctcatcaa aatcgggcat aaaacgcgtg ccatccgggc
    14581 gcttgagata agcgccttcg ccgcgcagtg cttccgttaa caggaaattg cgtgcctgtg
    14641 ggtgatacag cgcggtaggg tggaactgat taaattcgag attggcaacc cggcagcctg
    14701 cgcgccacgc catagcaatg ccatcgccag aagaaatatc cggattggtg gtgtactgat
    14761 aaacttttga agcaccgccg gttgccagta ccactgcttt tgcgtggcag gtttcaaccg
    14821 tttctttatt tcggttccat acccacgcgc caacaacccg tcgcgtgccc ggcaggccaa
    14881 ttttgtcaga aacaatcaga tcaaccgcgt tgctgcgctc cagcacgcga atattcggat
    14941 ggttctgcgc cttgcccacc agcgtggttt ctacttctct accggtggcg tcggcggcat
    15001 gaagaatacg acggtgacta tgtccacctt cacgagtcag atggtagctt tcttcgccat
    15061 tcggctgaat gtgggtatca aacaacaccc cctggtcgat tagccattgc acacaggatc
    15121 gtgcattact ggcgacaaat tcaactgcat ggcgatcgca aataccagcc ccggcaatca
    15181 atgtgtcttc cacatgcgag tcaatgctgt cagtttcatc aaacacggcg gcaataccgc
    15241 cctgggcata aaatgttgaa ccttccgtta ccgggccttt acttagaacg atgacctgat
    15301 gctggtcagc caggcgtagc gccagtgaaa gtccagctgc gccgctaccg ataatcaaca
    15361 cgtcacatga atgttcaggg agagtattca ttttctttgt ttaatttact aaacactgtt
    15421 tggtcagcat aacatcatgt tgtgcaaata aacacctgct attttaatat ttgttacagt
    15481 gactaaacac gctggctcag ggcggcgaga aaaagagaag ttactggctg gtggaggatt
    15541 aggtggtgaa ataaaaaggc cgttgggtta ctcttcaggc agttaaatgg gcatttctac
    15601 acagataatg cgatgttcag attctgtaga cttataatga tagataatga tccgtctaca
    15661 gcatgacaaa caaaaacaga tgcgttacgg aactttacaa aaacgagaca ctctaaccct
    15721 ttgcttgctc aaattgcagc taatggagtg gcgtttcgat agcgcgtgga aatttggttt
    15781 ggggagactt tacctcggat gagcgagcag ttaacggacc aggtcctggt tgaacgggtc
    15841 cagaagggag atcagaaagc ctttaactta ctggtagtgc gctatcagca taaagtggcg
    15901 agtctggttt cccgctatgt gccgtcgggt gatgttcccg atgtggtaca agaagctttt
    15961 attaaagcct atcgtgcgct ggattcgttc cggggagata gcgcttttta tacatggctg
    16021 tatcggattg ctgtaaatac agcgaaaaat tacctggttg ctcaggggcg tcgtccacct
    16081 tccagtgatg tggatgccat tgaagctgaa aacttcgaaa gtggcggcgc gttgaaagaa
    16141 atttcgaacc ctgagaactt aatgttgtca gaagaactga gacagatagt tttccgaact
    16201 attgagtccc tcccggaaga tttacgcatg gcaataacct tgcgggagct ggatggcctg
    16261 agctatgaag agatagccgc tatcatggat tgtccggtgg gtacggtgcg ttcacgtatc
    16321 ttccgagcga gggaagctat tgataacaaa gttcaaccgc ttatcaggcg ttgacgatag
    16381 cgggatactg gataagggta ttaggcatgc agaaagaaca actttccgct ttaatggatg
    16441 gcgaaacgct ggatagtgag ctgcttaacg aactggctca taacccagaa atgcagaaaa
    16501 cctgggaaag ctatcactta atccgtgact caatgcgggg tgatactccc gaggtgctcc
    16561 atttcgatat ctcttcacgc gtgatggccg ccattgaaga agagccagta cgtcaaccgg
    16621 cgacattgat cccggaagcc cagcctgcgc cgcatcaatg gcagaaaatg ccattctggc
    16681 agaaagtacg tccgtgggcg gcacagctta cccaaatggg cgtagcagca tgcgtatcgc
    16741 ttgcagttat cgttggcgtc cagcactata atgggcaatc tgaaacgtcc cagcagcccg
    16801 aaacgccagt atttaataca ctgccgatga tgggtaaagc cagcccggtt agtctgggag
    16861 taccttctga agcgaccgca aataatggtc aacagcagca ggtacaggag cagcgtcgtc
    16921 gcattaatgc aatgttgcag gattacgaac tgcaacgccg actccactct gaacagcttc
    16981 agtttgagca ggcacaaact cagcaagccg ctgtacaggt gccaggaatt caaactttag
    17041 gaacgcaatc gcagtaatga agcaactttg gtttgccatg tcattagtga caggtagcct
    17101 gttattctct gctaacgcct tggccactcc cgcgtccggg gcgttattac agcagatgaa
    17161 cctggccagt cagtcactga attacgagct gtcatttatc agcatcaata aacagggtgt
    17221 tgagtctctg cgttatcgac atgcacgcct cgataaccgt cctcttgcac aattgttgca
    17281 aatggatggc ccgcgccggg aagtggtaca gcgcggcaat gaaatcagct attttgaacc
    17341 gggacttgaa ccgttcacgc ttaatggcga ttacattgtt gattctctgc catcgctcat
    17401 ctataccgat ttcaaacgcc tttctcctta ctacgacttt atctctgtcg ggcgcacgcg
    17461 tattgctgat cgtctttgcg aagtcattcg tgtggttgcc cgagatggta cacgctacag
    17521 ctacatcgtg tggatggaca ccgaatcgaa attaccgatg cgggttgatc tccttgatcg
    17581 cgatggtgaa acgctggaac aatttcgcgt gattgctttt aacgtcaatc aggatatcgg
    17641 cagcagtatg cagacgctgg cgaaggcaaa tttgccgccg ttgctttctg ttcctgttgg
    17701 tgaaaaagct aaattcagct ggacgccaac ctggctgcca cagggtttta gcgaagtttc
    17761 cagtagtcga cgtccgctac cgacgatgga caacatgcct atcgaatcac gtctctattc
    17821 cgacggatta ttcagcttct cggtaaacgt taaccgcgct acgccatcga gcaccgatca
    17881 gatgttgcgc accggacgca gaaccgtcag tacaagcgta cgtgataacg ccgaaatcac
    17941 cattgttggt gaactgccgc cgcaaacggc gaaacgcatt gccgagaata ttaagttcgg
    18001 gacagcgcaa tgatcaaaga gtgggctacc gtcgtctcct gggaaaacgg gcaggcgctg
    18061 gtcagttgtg atgttaaagc ctcatgcagc agctgcgctt cacgcgccgg ttgcggtagc
    18121 cgtgtgttga ataaacttgg cccgcaaacc acgcatacca ttgtcgtacc ctgtgatgag
    18181 ccgctagtgc cggggcaaaa agtggaattg gggatcgccg aaggcagcct tcttagctcc
    18241 gcattactgg tttatatgtc gccgctggtg ggattattcc tcatcgcttc gctatttcag
    18301 ctactctttg cttctgacgt cgcagcatta tgtggtgcga tcctcggcgg tattggtggg
    18361 ttcctgattg cgcgcggcta ttcgcgtaag tttgctgccc gggcagaatg gcaaccgatc
    18421 atcttaagcg tggcattgcc gcctggcctt gtgcgatttg aaacatcttc ggaagacgcg
    18481 agccagtgat ttcactggct ttgttgcatt ttgcataaca aatgcgagga cgtttccata
    18541 taccacaatc catacggtat gaacatttcc tcgcctcaat gttgtagtgt agaatgcggc
    18601 gtttctatta atacagacgt taagctcaga acagcgactt ctaaaagcct ggttaaccgg
    18661 gcattaaggc acaataatca tactttatga agaatatacg taacttttcg atcatagctc
    18721 acattgacca cggtaaatcg acgctgtctg accgtattat ccagatctgc ggtggcctgt
    18781 ctgaccgtga aatggaggcg caggttctcg attccatgga tcttgagcgt gagcgtggca
    18841 ttaccatcaa agcgcaaagc gtgacgctgg actacaaagc gtctgacggc gaaacctatc
    18901 agcttaactt tatcgacacc ccgggccacg tagacttctc ctatgaagtt tctcgttcgc
    18961 tggctgcctg tgaaggtgca ttgctggtgg tcgacgccgg gcagggcgta gaagcgcaaa
    19021 ccctggcaaa ctgctacacc gccatggaaa tggatctcga agtggtgccg gtactgaaca
    19081 agattgacct gccggcagcc gatcctgaac gcgtggcgga agaaattgaa gatatcgtcg
    19141 gcatcgacgc caccgacgcg gtgcgctgtt cagcgaaaac cggcgttggc gtgcaagacg
    19201 ttctcgaacg cttggtgcgc gacattccgc cgccggaagg cgatccggaa ggcccattgc
    19261 aggcgctgat tatcgactcc tggttcgaca actacctggg cgttgtttca cttatccgta
    19321 ttaaaaacgg caccctgcgt aagggcgaca aagtgaaagt catgagcacc gggcagacct
    19381 ataacgccga tcgtctgggc atcttcacgc cgaagcagat tgaccgcact gaactgaaat
    19441 gtggcgaagt aggctggctg gtatgtgcga ttaaagatat ccacggcgct ccagtaggcg
    19501 ataccttaac actggcgcgt aatccggcag aaaaggcgct gcctggcttt aagaaagtca
    19561 aacctcaggt atatgctggt ctgttcccgg taagttccga cgactatgaa gccttccgtg
    19621 acgcgctggg taaactcagc ctgaacgatg cctcactgtt ctatgagccg gaaagctcca
    19681 gcgcgttggg ctttggtttc cgctgcggct tccttggcct gctgcacatg gagatcatcc
    19741 aggaacgtct ggaacgtgaa tacgatctgg atctgatcac cactgcgccg actgtagtgt
    19801 atgaagttga aaccacgtca agagaagtta tctacgtcga cagcccatcc aagctgccag
    19861 cggtaaataa catttacgaa ctgcgcgagc cgattgcaga gtgtcacatg ctgctgccgc
    19921 aggcatatct cggcaacgtt attacgctgt gcgtagaaaa acgcggcgtg cagaccaata
    19981 tggtttacca cggtaatcag gtggcgctga cgtacgagat cccgatggcg gaagtggtgc
    20041 tcgacttctt cgatcgcctg aaatctacct cgcgtggtta tgcgtctctg gattacaact
    20101 tcaaacgctt ccaggcgtcc gacatggtac gtgtagacgt attaatcaac ggtgaacgtg
    20161 ttgatgcatt ggcgctgatc acccaccgtg gtaattcgca aaaccgcggt cgcgagctgg
    20221 tggagaagat gaaagatctg atcccacgcc agcagtttga tatcgccatt caggcagcga
    20281 ttggtacgca catcattgcg cgctccaccg tgaaacagct gcgtaaaaac gtactggcta
    20341 aatgttatgg cggcgatatc agccgtaaga aaaagctgct gcagaagcag aaagaaggta
    20401 agaaacgcat gaagcagatc ggtaacgtcg agctgccgca ggaagcgttc ctcgccattc
    20461 tgcacgtcgg caaagacaac aaataaccct taggagttgg catggcgaat atgtttgccc
    20521 tgattctggt gattgccaca ctggtgacgg gcattttatg gtgcgtggat aaattctttt
    20581 tcgcacctaa acggcgggaa cgtcaggcag cggcgcaggc ggctgccggt gactcactgg
    20641 ataaagcaac gctgaaaaag gttgcgccga agcctggctg gctggaaacc ggtgcttctg
    20701 tttttccggt actggctatc gtattgattg tgcgttcgtt tatttatgaa ccgttccaga
    20761 tcccgtcagg ttcgatgatg ccgactctgt taatcggtga ttttattctg gtagagaagt
    20821 ttgcttatgg cattaaagat cctatctacc agaaaacgct gatcgaaacc ggtcatccga
    20881 aacgcggcga tatcgtggtc tttaaatacc cggaagatcc aaagcttgat tacatcaagc
    20941 gcgcggtggg tttaccgggc gataaagtca cttatgatcc ggtctcaaaa gagctgacga
    21001 ttcaaccggg atgcagttcc ggccaggcgt gtgaaaacgc gctaccggtc acttactcca
    21061 acgtggaacc gagcgatttc gttcagacct tctcacgccg taatggtggg gaagcgacca
    21121 gcggattctt tgaagtgccg aaaaacgaaa ccaaagaaaa tggaattcgt ctttccgagc
    21181 gtaaagagac actgggtgat gtgacgcacc gtattctgac agtgccgatt gcgcaggacc
    21241 aggtggggat gtattaccag cagccagggc aacaactggc aacctggatt gttccgccgg
    21301 gacaatactt catgatgggc gacaaccgcg acaacagcgc ggacagtcgt tactggggct
    21361 ttgtgcctga agcgaatctg gtcggtcggg caacggctat ctggatgagc ttcgataagc
    21421 aagaaggcga atggccgaca ggtgtgcgct taagtcgcat tggcggtatc cattaatagc
    21481 catcttcgtt cacgttgtcg ccgttatggc gacaacgtga attatttatg agataaatct
    21541 cccgtggcta acgacatccc ccgtcgttgt gtatagaata ttcccccgaa gtttaaggtt
    21601 ggcacctcca ggttgccacg gcacacgaaa cagcgttggt ccccatatac cggtaaactg
    21661 aaactgcagt gaagcagtta gccgagccat gtatatcagg tctgtttcgt gtgctgaatt
    21721 gttgacgcat ttatttattg gtatcgcatg aaccccatcg taattaatcg gcttcaacgg
    21781 aagctgggct acacttttaa tcatcaggaa ctgttgcagc aggcattaac tcatcgtagt
    21841 gccagcagta aacataacga gcgtctggaa tttttaggtg actctattct gagctacgtt
    21901 atcgccaatg cgctttatca ccgtttccct cgtgtggatg aaggcgatat gagccggatg
    21961 cgcgccacgc tggtccgtgg taatacgctg gctgaactgg cgcgcgaatt tgagttaggt
    22021 gagtgcttac gtttagggcc aggtgaactt aaaagcggtg gatttcgtcg tgagtcaatt
    22081 ctcgccgaca ccgtcgaagc attaattggt ggcgtattcc tcgacagtga tattcaaacc
    22141 gtcgagaaat taatcctcaa ctggtatcaa actcgtctgg acgaaattag cccaggcgat
    22201 aaacaaaaag atccgaaaac gcgtctgcag gaatatttgc agggtcgcca tctgccgctg
    22261 ccaacttatc tggtagtcca ggtacgtggc gaagcgcacg atcaggaatt tactatccac
    22321 tgccaggtca gcggcctgag tgaaccggtg gttggcacag gttcaagccg tcgtaaggct
    22381 gagcaggctg ccgccgaaca ggcgttgaaa aaactggagc tggaatgagc atcgataaaa
    22441 gttactgcgg atttattgct atcgtcggac gtccgaacgt tggcaaatcc acattgttga
    22501 acaaactgct ggggcagaag atctccatta cctcccgcaa ggcgcaaaca actcgtcacc
    22561 gcattgtggg gatccatact gaaggcgcgt atcaggcgat ctacgttgat accccaggcc
    22621 tgcatatgga agaaaaacgc gccattaacc gtctgatgaa caaagcggcg agcagctcca
    22681 ttggcgatgt tgagctggtg atttttgtcg tagaaggcac tcgctggacg ccggacgatg
    22741 aaatggtgct caacaaactg cgcgatggca aagcgccggt aatcctcgcg gtgaacaaag
    22801 tggataatgt gcaggaaaaa gccgatctgc tgccacactt acagttcctg gcaagccaga
    22861 tgaacttcct cgatatcgtg ccgatctctg ccgaaaccgg gctgaatgtc gacactattg
    22921 cagcaatcgt gcgtaagcat ctgcctgaag cgacccatca cttcccggaa gattacatca
    22981 ccgatcgctc acagcgtttt atggcgtctg aaattatccg cgaaaaactg atgcgttttc
    23041 tcggcgctga actgccgtac tccgtgaccg tggagatcga acgtttcgtc tctaacgaac
    23101 gcggcggtta tgacatcaac ggtttgattc tcgttgagcg tgaagggcag aagaagatgg
    23161 tcattggcaa caaaggggcc aagatcaaaa ccatcgggat tgaagcgcgt aaagacatgc
    23221 aggaaatgtt cgaagcgcct gttcaccttg agctgtgggt aaaagtgaaa tccggttggg
    23281 ccgacgacga acgcgcactg cgcagtctcg gttatgttga cgatctttaa gagtaactcc
    23341 gatggaaggc tggcagcgcg catttgtcct gcatagtcgc ccgtggagcg aaaccagcct
    23401 gatgctggac gtcttcacgg aggaatcggg tcgcgtgcgt ctggttgcca aaggcgcacg
    23461 ctctaaacgc tctactctga aaggtgcatt acagcctttc acccctctct tgctacgttt
    23521 tggcgggcgt ggcgaagtca aaacgctgcg cagtgctgaa gctgtctcgc tggcgctgcc
    23581 attaagcggt atcacgcttt acagcggtct gtacatcaac gaacttctct cccgcgtact
    23641 ggaatacgag acgcgcttct ctgaactctt tttcgattac ttgcactgca ttcagtctct
    23701 tgccggggtc actggtacgc cagaacccgc gttgcgccgc tttgaactgg cactgctcgg
    23761 gcatctgggc tatggcgtca attttaccca ttgtgcgggt agcggcgagc cggtagatga
    23821 caccatgacg tatcgttatc gcgaagaaaa agggtttatc gcaagcgtcg ttatcgacaa
    23881 taaaacgttc accggaaggc agttaaaagc gttaaacgcg cgggaatttc ctgacgcaga
    23941 cacactgcgc gccgcgaaac gctttacccg catggcgctt aagccgtatc ttggcggtaa
    24001 accattaaag agcagggaac tgttccggca gtttatgcct aagcgaacgg tgaaaacaca
    24061 ttatgaatga tgaggattgt catggctgaa ttactgttag gcgtcaacat tgaccatatt
    24121 gcaacactgc gtaacgcgcg cggtactgct tacccggatc cggtgcaggc ggcgtttatt
    24181 gctgagcagg cgggagcgga cggcattacc gtgcatttac gtgaagaccg ccgccacatt
    24241 accgaccgcg atgtgtgcat cctgcgccag acgctggata cccgcatgaa tctggagatg
    24301 gcggtgaccg aagagatgct ggcgatcgcc gttgagacga agccacattt ttgctgtctg
    24361 gtaccggaaa agcgtcagga agtaacaacc gaaggcggcc tggacgtcgc agggcagcgt
    24421 gaaaaaatgc gcgatgcctg caaacgtctg gcagatgccg ggatccaggt ttctctgttt
    24481 atcgacgccg atgaagagca gatcaaagct gcggcagagg ttggcgcacc gtttatcgag
    24541 atccacaccg gttgctatgc tgatgccaaa actgacgccg aacaggcgca agagttggcg
    24601 cgtatcgcca aagccgcgac ctttgccact agtctcggtc tgaaagttaa cgccggacac
    24661 ggtctgacct atcacaacgt gaaagccatt gccgccatcc ctgagatgca tgaactgaat
    24721 atcggtcatg ccattattgg tcgtgcagtg atgaccggac tgaaagatgc ggtggcagaa
    24781 atgaagcgtc tgatgctgga agcgcgtggc taatggcaat attaggttta ggtacggata
    24841 tcgtagagat cgctcgcata gaagcggtga tcgcccgatc cggtgagcgc ctggcacgcc
    24901 gcgtattaag cgataacgaa tgggaaatct ggaaaacgca ccaccagcca gtgcgttttc
    24961 tggcgaagcg ttttgctgtg aaagaagcgg cggcaaaagc atttggcaca gggatccgca
    25021 atggtctggc gtttaatcag tttgaagtat tcaatgatga gctcggcaaa ccacggctac
    25081 ggctatgggg tgaggcatta aaactggcgg aaaagctcgg cgttgtaaat atgcatgtaa
    25141 cgcttgccga tgagcgccac tatgcttgtg ccacggtaat tattgaaagt taaaataata
    25201 ccgttctctt tataaagtaa aacccccgaa ctggtaagga acgggggttt tactttttaa
    25261 ctttaatttt gtgcagcaca cgattccaac gaaaatgatt atggatcaat ttcgttgacc
    25321 tgtacaagca acttgcaatc tctgacataa aaaacgcgag cctttacgaa gaaatcgaca
    25381 ttgatgaaaa gattaacgtg accgcttttt gataagtaca ttaaaatcgg tttcgttatt
    25441 ggcaattttg ctgtgcttta caccatgcca ctgaattccc ccattgaaac gagtggtgtc
    25501 gtcaaagctc tggtgtggag tgcagcactc gattccaata actcgcacgt tcagttttgg
    25561 ggagatgtaa gggctaatct gaacggctgc attccttgtt taaggaaaaa cgaatgactg
    25621 attgccgata cctgattaaa cgggtcatca aaatcatcat tgctgtttta cagctgctcc
    25681 ttttgttctt ataacacaag gaaacgtact taaggtgcgt ccggtgaacc aatcggacgc
    25741 gcctttaata actataaata agtgtctggg cagatactat ataaattaac ttagtgaatg
    25801 attatgctaa tgtca
//
LOCUS       DAPOXO010000075        25645 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPOXO010000075 DAPOXO010000000
VERSION     DAPOXO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25645
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.075"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            182..655
                     /locus_tag="ROH59_003658"
     CDS             182..655
                     /locus_tag="ROH59_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX4806095.1"
                     /translation="MKTLSQNTTSSACAPETGLQQLVATIVPDEQRISFWPQHFGLIP
                     QWVTLEPRVFGWMDRLCENYCGGIWNLYTLNNGGAFMAPEPDDYDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRIID"
     gene            671..1147
                     /locus_tag="ROH59_003659"
     CDS             671..1147
                     /locus_tag="ROH59_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HDX4806096.1"
                     /translation="MQQISFLPGEMTTRERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEHGLL"
     gene            1210..1431
                     /locus_tag="ROH59_003660"
     CDS             1210..1431
                     /locus_tag="ROH59_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDX4806097.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            1450..2094
                     /locus_tag="ROH59_003661"
     CDS             1450..2094
                     /locus_tag="ROH59_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of toxin-antitoxin stability system"
                     /protein_id="HDX4806098.1"
                     /translation="MSRIITTTVYTLHELSSTAQEKARDWYRQHHADSNWYENVYEDF
                     RAVCGIFGIDLRQRVFRLSNGRFMEEACIWFSGFCSQGDGACFEGRWHWQPATARRLR
                     EYATQDHELHRIADALQAVQKRNFWQLQAEIHHRGRYCHPYSMDITVTRNSPTGQAMT
                     ADAEAAVSEALRDLAFWLYRQLENEYDRLTSDAAVDEALLINEYTFTEAGLRAG"
     gene            2110..2478
                     /locus_tag="ROH59_003662"
     CDS             2110..2478
                     /locus_tag="ROH59_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDX4806099.1"
                     /translation="MSDKLHETNYPDDHNDRLWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCKAD
                     TLSSCGYVYLAVYPTPEMKN"
     gene            2567..2941
                     /gene="cbtA"
                     /locus_tag="ROH59_003663"
     CDS             2567..2941
                     /gene="cbtA"
                     /locus_tag="ROH59_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HDX4806100.1"
                     /translation="MKTLPVLPGQAASSRPSPVEIWQILLSRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSACTRSQLINSIDILRARRATG
                     LMTSDNYRTVNNITLGKYPEAK"
     gene            2938..3132
                     /locus_tag="ROH59_003664"
     CDS             2938..3132
                     /locus_tag="ROH59_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806101.1"
                     /translation="MMTLEADSVNVQALDMGHIVVDIDGVNITELINKAAENGYSLRV
                     VDDRDSTETPATYASPHQLL"
     gene            3145..3258
                     /locus_tag="ROH59_003665"
     CDS             3145..3258
                     /locus_tag="ROH59_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDX4806102.1"
                     /translation="MQGIVPLTTETALLSCIKQAREDVLTLRHLQLLHQNR"
     gene            complement(3547..3693)
                     /locus_tag="ROH59_003666"
                     /pseudo
     CDS             complement(3547..3693)
                     /locus_tag="ROH59_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            3747..3929
                     /locus_tag="ROH59_003667"
     CDS             3747..3929
                     /locus_tag="ROH59_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HDX4806103.1"
                     /translation="MNHPVIGVVTKADLASMEQISLVTSWLREAGAHNVLVTSAVNNN
                     GVTELFALLHTEEGCC"
     gene            complement(4030..4359)
                     /locus_tag="ROH59_003668"
     CDS             complement(4030..4359)
                     /locus_tag="ROH59_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HDX4806104.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(4531..5589)
                     /locus_tag="ROH59_003669"
     CDS             complement(4531..5589)
                     /locus_tag="ROH59_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDX4806105.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIA
                     PASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQ
                     QILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLDNHHDLKVLETPIYGYVWLNME
                     TAHQLELLSNLICRALRK"
     gene            complement(5787..6260)
                     /gene="sbmC"
                     /locus_tag="ROH59_003670"
     CDS             complement(5787..6260)
                     /gene="sbmC"
                     /locus_tag="ROH59_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HDX4806106.1"
                     /translation="MNYEIKQEDKRTVAGFHLVGPWEQMVKKGFEQLMMWIDSKNIVP
                     KEWVAVYYDNPDETPAEKLRCDTVVTVPNNFTLPENSEGVILTEISGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH"
     gene            complement(6379..7545)
                     /gene="dacD"
                     /locus_tag="ROH59_003671"
     CDS             complement(6379..7545)
                     /gene="dacD"
                     /locus_tag="ROH59_003671"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HDX4806107.1"
                     /translation="MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGREEEARKLLR
                     WGQQNFTTVQILHRGKKVGTERIWYGDKENIALGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            7754..9181
                     /gene="sbcB"
                     /locus_tag="ROH59_003672"
     CDS             7754..9181
                     /gene="sbcB"
                     /locus_tag="ROH59_003672"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HDX4806108.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDNEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNVFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVILVDLAGDISPLLELDS
                     DTLRERLYTAKADLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYADELQML
                     AQQYADDKEKVALLKALWQYAEEIV"
     gene            complement(9292..9750)
                     /gene="tnpA"
                     /locus_tag="ROH59_003673"
     CDS             complement(9292..9750)
                     /gene="tnpA"
                     /locus_tag="ROH59_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element IS200C family
                     transposase"
                     /protein_id="HDX4806109.1"
                     /translation="MGNEKSLAHTRWNCKYHIVFAPKYRRQVFYREKCRAIGCILRKL
                     CEWKSVRILEAECCADHIHMLVEIPPKMSVSGFMGYLKGKSSLMPYEQFGDLKFKYRN
                     REFWCRGYYVDTVGKNTAKIQDYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
     gene            complement(9967..11325)
                     /gene="plaP"
                     /locus_tag="ROH59_003674"
     CDS             complement(9967..11325)
                     /gene="plaP"
                     /locus_tag="ROH59_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HDX4806110.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQIVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(11315..11377)
                     /gene="yoeI"
                     /locus_tag="ROH59_003675"
     CDS             complement(11315..11377)
                     /gene="yoeI"
                     /locus_tag="ROH59_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HDX4806111.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            complement(11592..12521)
                     /locus_tag="ROH59_003676"
     CDS             complement(11592..12521)
                     /locus_tag="ROH59_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4806112.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLAQEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDGKSAI"
     gene            complement(12567..13391)
                     /locus_tag="ROH59_003677"
     CDS             complement(12567..13391)
                     /locus_tag="ROH59_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4806113.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSG
                     IDSYLLRMEPELVCDSDDLDALMDADALVITLPARRSGPGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            complement(13474..13728)
                     /gene="yoeB"
                     /locus_tag="ROH59_003678"
     CDS             complement(13474..13728)
                     /gene="yoeB"
                     /locus_tag="ROH59_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HDX4806114.1"
                     /translation="MKLIWSEESWDDYLYWQEADKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHLLVYAVTDDSLLIAACRYHY"
     gene            complement(13725..13976)
                     /gene="yefM"
                     /locus_tag="ROH59_003679"
     CDS             complement(13725..13976)
                     /gene="yefM"
                     /locus_tag="ROH59_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HDX4806115.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSDKGTEKDIIE"
     gene            14259..14309
                     /gene="hisL"
                     /locus_tag="ROH59_003680"
     CDS             14259..14309
                     /gene="hisL"
                     /locus_tag="ROH59_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HDX4806116.1"
                     /translation="MTRVQFKHHHHHHHPD"
     misc_feature    14285..14408
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            14455..15354
                     /gene="hisG"
                     /locus_tag="ROH59_003681"
     CDS             14455..15354
                     /gene="hisG"
                     /locus_tag="ROH59_003681"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDX4806117.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     gene            15360..16664
                     /gene="hisD"
                     /locus_tag="ROH59_003682"
     CDS             15360..16664
                     /gene="hisD"
                     /locus_tag="ROH59_003682"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDX4806118.1"
                     /translation="MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVK
                     TRGDEALREYSAKFDKTTVTALKVSADEIAAASERLSDELKQAMAVAVKNIETFHTAQ
                     KLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLC
                     SPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDAD
                     MARRVAEAVERQLAELPRAETARQALSASRLIVTNDLAQCVEISNQYGPEHLIIQTRN
                     ARDLVDSITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNVLKEQA"
     gene            16661..17731
                     /gene="hisC"
                     /locus_tag="ROH59_003683"
     CDS             16661..17731
                     /gene="hisC"
                     /locus_tag="ROH59_003683"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDX4806119.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDA
                     ILYCPPTYGMYSVSAETIGVECRTVPTLENWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAER
                     EYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            17731..18798
                     /gene="hisB"
                     /locus_tag="ROH59_003684"
     CDS             17731..18798
                     /gene="hisB"
                     /locus_tag="ROH59_003684"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HDX4806120.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQ
                     KAGYKLVMITNQDGLGAQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDREALNWPMIGE
                     QLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            18798..19388
                     /gene="hisH"
                     /locus_tag="ROH59_003685"
     CDS             18798..19388
                     /gene="hisH"
                     /locus_tag="ROH59_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDX4806121.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIEED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGTAGAKLLKNFLEM"
     gene            19388..20125
                     /gene="hisA"
                     /locus_tag="ROH59_003686"
     CDS             19388..20125
                     /gene="hisA"
                     /locus_tag="ROH59_003686"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDX4806122.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPAKRQIPLIKTLVTGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVFLYEEVCARYPQVAFQSSGGIGDINDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNA"
     gene            20107..20883
                     /gene="hisF"
                     /locus_tag="ROH59_003687"
     CDS             20107..20883
                     /gene="hisF"
                     /locus_tag="ROH59_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDX4806123.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
                     DWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC"
     gene            20877..21488
                     /locus_tag="ROH59_003688"
     CDS             20877..21488
                     /locus_tag="ROH59_003688"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDX4806124.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TLESGKVTFFSRTKQRLWTKGETSGNILNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLATVIENLRKRHQ"
     gene            complement(21674..22651)
                     /gene="wzzB"
                     /locus_tag="ROH59_003689"
     CDS             complement(21674..22651)
                     /gene="wzzB"
                     /locus_tag="ROH59_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310855.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen chain length determinant protein
                     WzzB"
                     /protein_id="HDX4806125.1"
                     /translation="MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIAL
                     AIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQATPKVSDLQETLIGRFSSA
                     FSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVN
                     QELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQIQ
                     QTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSSYYQTRQNLLDIDNLDVDKLDIHA
                     YRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGVGIVLGRNALRNYNAK"
     gene            complement(22797..23963)
                     /gene="ugd"
                     /locus_tag="ROH59_003690"
     CDS             complement(22797..23963)
                     /gene="ugd"
                     /locus_tag="ROH59_003690"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HDX4806126.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGTIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            complement(24210..25616)
                     /gene="gndA"
                     /locus_tag="ROH59_003691"
     CDS             complement(24210..25616)
                     /gene="gndA"
                     /locus_tag="ROH59_003691"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDX4806127.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQRAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
BASE COUNT         6491 a         6658 c         6336 g         6160 t
ORIGIN      
        1 aggcaatggc atctggccat ccgtctgtga ccggaacggt tacgcgtacg gctgtccgga
       61 atttcagccg aatatcattc atccctgata ttaccgggtc tcacggtcag tgatgaacgt
      121 gatgttgcca gctcccgacc tttactccct ctcatttatt cacattacaa ggatttcata
      181 catgaaaaca ttgtctcaga acaccacctc ttcggcctgt gcaccggaga ctggcctgca
      241 acaactggtt gccaccatag tccctgatga acagcgcatc agcttctggc cgcagcattt
      301 tggcctcatt ccacagtggg tgaccctgga gccccgtgtc ttcggctgga tggaccgtct
      361 gtgcgaaaac tactgcggtg gtatctggaa tctgtacacc ctgaacaacg gcggggcatt
      421 tatggcccct gaaccggatg actatgatga cgaaacatgg gtactgttca atgccatgaa
      481 cggtaaccgc gctgaaatga gcccggaagc cgccggcatt gccgcctgtc tgatgacgta
      541 cagtcatcac gcctgccgta cggagtgtta tgccatgacg gttcattatt accgtctgcg
      601 ggattacgcc ctgcagcatc cggaatgcag cgccattatg cgcattattg actgaaaggg
      661 ggccggaaca atgcaacaga tttcctttct gcccggagaa atgacaacca gagagcgcag
      721 cctcattcag cgggccctga aaaccctgga ccgccatctt catgaacccg gcgtggcctt
      781 cacctccacc cgtgcggcac gggaatggct gattctgaac atggcgggac tggagcgtga
      841 agaattccgg gtgctgtatc tgaataacca gaatcagctg attgccggtg aaaccctctt
      901 caccggcacc atcaaccgca cggaagtcca tccccgggaa gtgattaaac gcgccctgta
      961 tcacaatgcc gcagccgtgg tgctggcgca caatcacccg tccggtgaag tcacacccag
     1021 taaggcagac cggcttatca ccgaacgtct ggtacaggca ctgggcctgg tggatatccg
     1081 ggtgccggac catctgatag tcggtggcag ccaggttttc tcctttgccg aacatggtct
     1141 gctttaaccc gtcacaacca catcacacct gttttcactt ttatcttctg tcttcagagg
     1201 tatcccacta tgaaaatcat cacccgtggc gaagccatgc gtattcaccg tcagcatcct
     1261 gcatcccgtc tttttccgtt ctgtaccggc aaataccgct ggcacggcag tgctgaagcg
     1321 tataccggtc gtgaagtgca ggatattccc ggtgtgctgg ccgtgtttgc tgaacgccgt
     1381 aaggacagtt ttggcccgta tgtccggctg atgagcgtca ctctgaactg agtcagtaag
     1441 ggcattctga tgagcagaat tatcaccacc accgtgtata cactgcatga gctatcctcc
     1501 accgcacagg aaaaagcccg cgactggtac cgtcagcatc atgctgacag caactggtat
     1561 gaaaacgtgt atgaggactt cagggcggtc tgtggcattt tcggaattga cctccgccag
     1621 cgcgttttcc ggctcagcaa cggcaggttt atggaagagg cgtgcatctg gttcagcgga
     1681 ttctgcagcc agggggacgg agcctgtttt gaaggacgct ggcactggca gccagcaaca
     1741 gccagaaggc tccgggagta tgccacacag gaccatgaac tccatcgtat cgcggatgcc
     1801 ctgcaggcgg tgcagaaacg taacttctgg caactgcagg ctgaaatcca ccaccgggga
     1861 cgttactgcc atccgtacag catggatatc actgttaccc ggaacagtcc gactggtcag
     1921 gctatgacag ccgatgcgga agccgctgtc agcgaagccc tgcgcgacct ggccttctgg
     1981 ttgtaccgtc agctggaaaa cgagtacgac aggctgacct ctgatgccgc tgtggatgag
     2041 gcccttctca tcaacgaata caccttcacc gaagccggtc tgcgcgccgg ctgacctgag
     2101 gactttatcg tgtcagacaa actccatgag acaaattatc ccgacgacca taacgaccgc
     2161 ctctggtggg gactgccctg caccgtgacg ccctgtttcg gggcacgtct ggtgcaggag
     2221 ggtaaccggt tgcattacct tgccgaccgc gccggtatca gaggcctgtt cagcgatgca
     2281 gatgcgtacc acctggacca ggcctttccg ctgctgatga aacaactgga actcatgctc
     2341 accagcggtg aactgaatcc ccgccatcag cataccgtca cgctgtatgc aaaagggctg
     2401 acctgcaaag ccgataccct cagcagttgt ggttacgttt atctggctgt ttatccgacg
     2461 cccgaaatga aaaattaact ctccagaata gccttctgct acggcctggt gttttcacca
     2521 cgccactttt ccatttttat atctgcatat caggaaaatc ttcagtatga aaacattacc
     2581 tgtattaccc gggcaggcgg ccagttctcg cccgtctcct gttgaaatct ggcagatact
     2641 gctgtcccga ctgctggacc agcactatgg cctcacactg aatgacacac cgtttgccga
     2701 tgaacgtgtg attgagcagc atattgaggc aggcatttca ctgtgtgatg cggtgaactt
     2761 tctcgtggaa aaatacgcgc tggtgcgtac cgaccagccg ggattcagcg cctgtacccg
     2821 ctctcagtta ataaacagca tcgatatcct ccgggctcgc agggcgaccg gcctgatgac
     2881 cagcgacaat tacagaacgg taaataacat taccctgggt aagtatccgg aggcgaaatg
     2941 atgacactgg aagccgacag cgttaacgta caggcgctgg atatggggca cattgtcgtt
     3001 gacattgatg gtgttaatat cactgaactg attaataagg ccgctgaaaa cggttattca
     3061 ctccgcgtgg tggatgaccg tgactctacc gaaacaccgg caacttatgc cagccctcac
     3121 cagttgctgt aagacaatgc agtgatacag ggtatagtgc cattaaccac agaaacagca
     3181 ctgttgtcct gtattaagca ggcaagagaa gatgtcctta ccctgcgcca tctgcagctt
     3241 ctgcaccaga accggtgaat ctcactcaac aggcttcatt tcccctgacg ccagcctgaa
     3301 tacagctggc gttttcattt ataaacagaa aggaaaaccg ataataatgg aatggacgcc
     3361 ccgaccatga agcaacggta ggatattact gataaacctt ccagtggagg tgcgttatgg
     3421 ccgttttaac gattagcatt gacctgacaa aaaatgaatt ccaaatccac ggtctgggta
     3481 ggaacagaaa aatctaagct cagaaaacgg attaaagtaa gcgtcaacgg agcaccgtat
     3541 tgacgcttat ttattggtga gaactacgtt ccatggcagg agttcgtcaa cacggttgga
     3601 gggccattcc ggcagtatgc tcagaatatg gcgcagatac gcttccggat cgataccgtt
     3661 cagacggcag gtgcctgctt ttccggcaac aagcaggaat ctcagcgctg aagcaggaat
     3721 tagaggtaaa aacgccctac cgggccatga atcacccggt cattggagta gtaaccaaag
     3781 cagatttagc cagcatggaa caaatatctt tggtgacaag ttggttacgg gaagctggag
     3841 cgcacaacgt gttagtaacc agtgcagtta ataacaatgg agttacagaa ctttttgcct
     3901 tgctgcatac agaagaaggc tgttgttaat ttcgattggt tctcagatga gaatgatgac
     3961 ggtgatacac agataagaat caatgagcaa tgagggttgc cgggcaaccc tcattgaata
     4021 aaacgggaat tacttcgctt cgccgttttt catttcgccc atagctttca gctttttgga
     4081 gatatcgcgg cgttctttgg agagctcggc atttttgatg atgtaatcgt caacgcgatc
     4141 ttcatagtca cctttcatgc tggcgatgat gccctggatt gcttcaacgc tcatccctgg
     4201 cttgatgtaa tcgctcaggt tgtccagcaa caggacgcgc ttctggttgt cacggatctt
     4261 tttctcaacg tcctgaattt cacgttgcag tttgttctta cgacggaaca gacgaacaaa
     4321 ttccagtacg tcctggaatg aaggcttggt agtttccatt tttatacccc tgataatgtg
     4381 agagtcggat tcgtttaagc aaccgctatt cgttagggcc aacattactc atagctgccg
     4441 cagatgacaa tgcttttatc ccttttcact atcataccct ttatccttgc tgaatcgaag
     4501 cagcagcaag atgattctga agttcaggaa ttatttgcgc aaggcccggc aaatcagatt
     4561 cgatagcaac tcaagctgat gtgccgtttc catgttcagc cacacataac catagattgg
     4621 tgtttccaag actttcaggt catggtggtt atcgagcaac tgacgcagct cttccacagc
     4681 atcgttcaat ttttccgtat tggcaaaaac cggctgcgga ttaccttcgt acagcgcatg
     4741 aacaaggctc agcagtattt gctgcatcat gtgctgggta tcacgaagtt tttgcgcgtt
     4801 caataacacg aaatggctgg ggcgcgtggc ccagtatgca ttgatttgca actccagcat
     4861 acaaaccaga ttgcgattaa tggtctggat accttcatat atcgatttgg gaatacgggt
     4921 ttctttgctg gcgggcgcaa tcagcccacg cattttcacg gcatcggtca ggagtttttg
     4981 tagatggctt tccagacgtg ggcgttcgag taagttcggt gagaatgcag attgatagac
     5041 ccgattatac tcggtcagac ttttcgccag ttgaatgcgc cagtggatga acgcccgttg
     5101 tggccagata ccggtaaaca acattgccag taaagagccg aggatcacat cgccgcttcg
     5161 ccataacgcc gtatcaattt cacctgtcgg ggaacccaca acaattgcca gcgtcacccc
     5221 aatcaataat ccttgatacg gtttcttgcc cagcgccagc caaccgcaaa gaaacatcgc
     5281 cgccgcgcac cagactaaca tcagcggtaa cgaaattaac tccagttgca gagcgataag
     5341 acctaaaatc gaacccaaca ccgtaccgcc aatacgttcg aaggcacgag ggacaacgtt
     5401 cccccagaac gagattggcc ccataatcac caccatggtg accagcggcc aggtgctttc
     5461 cgggatagta aacaggcgga taatgagaaa agtgagcagg aatgccagcg cgacccgagt
     5521 accatgcaca atgcggtaat ggcggtatac ccggatttca aacgggctta atgacttatc
     5581 ggcacgcacg cagaaactcc gtaatgaaga tgaaaagcgc tcataacaca tctgtcggcc
     5641 agaaggcgcg cctctgagtt atccgacgga cataccggga acagtgtaat ttcccggcag
     5701 gagcgaaaaa tttgaaaggc gcatcttact cttttcgctt tcaaaaaaag agtggtcttc
     5761 gcgttaacac accgccctga gatgaattag tgatgttttg gctgcaccgc aacatacatt
     5821 tcgatatccc agtacccatc ttccgcgcca ttgttcaagt aaacctcgaa gcagggcttt
     5881 ggtaacattt cataagcact gtcctgcaag aggctattaa agaactgata ccagggttta
     5941 gcaaaatcat caccgactac acgagccacc gccaccgcat actgaccacc tgaaatttct
     6001 gtcagaatga cgccctcact gttttcgggg agcgtaaagt tattcggtac cgtcacgacg
     6061 gtgtcgcagc gtaatttttc ggcgggtgtt tcatctggat tgtcgtaata gacagcaacc
     6121 cactccttcg gcacaatatt tttgctatct atccacatca tcaactgctc aaaacctttc
     6181 tttaccatct gctcccacgg gccaacaaga tggaaacctg caacggtacg tttatcttcc
     6241 tgcttaatct cgtagttcat gacgcctcca ctaacactgt ttttatatac agtatagttg
     6301 caatattaaa accacaagga atgagtgttg attatgcgag cagactcgca ctcctgccag
     6361 tctgctgcaa aagaaaggtc aggccttatg gtggaaataa tcactcaggc gggaaaacat
     6421 gctgccttcc ccgacagatt ccagggtaac cagcggccag tgcgccacct gtttatcacg
     6481 gtcgtaaagt tcaatttccc ctacccgctg atgggcgcta attggcgcgg tgagttcttt
     6541 accatcaagg gtatatttgg ctttgatatg tggaatttcg gctttcggta gcaccatcca
     6601 gaactcttgt tccgttccca gggcgatatt ttctttatca ccataccaga tgcgttccgt
     6661 accgaccttt ttcccacggt gcaaaatttg caccgtagta aagttttgtt gcccccaacg
     6721 cagtaatttt cttgcctctt cctcacgacc ttttgcgctg tcagccccca ttaccactgc
     6781 aatgaggcga cgctgcccgt ctacagccga agcaataaga ttaaacccgg caccagaagt
     6841 atggcccgtt ttcaggccgt caacattcat ggttttatcc cacaataacc cgttacggtt
     6901 ttgctgggtg ataccgttcc aggtgaggct tttctcactg tacatatgat aaaactcggg
     6961 ctcgccgtgg atgatagcgc gagaaagcac ggctaaatca taagccgagc tatgctggcc
     7021 aggtgcatcc agaccatgca ctgtttcaaa atgcgtatcc ttgagatgca gcttctcggc
     7081 atagttgttc atcatttcaa caaactgccg ttgcccaccg gcaatatagt cagccagagc
     7141 aacacaagcg tcatttccgg aatccacaat taaaccacgg cttaaatcac gtaccgatac
     7201 gcgatcgccc tctttcaaaa acatcagtga agaaccgaca aacaccggat tatctttcgc
     7261 ccacgcatca cgccccacgg tgacaatatc gtctggcgta atgcgatgac tatcgatagc
     7321 gcgatccacg acatagcccg tcatcagctt tgtcaggctg gcgggattgc gctgttgatg
     7381 ctcattaccc gcggtgagaa tctgaccggt ggtgtaatcc atcaataccc aggacccggc
     7441 atgaatctct ggaggctgag gtgaaaaagg aatgttttcc gccgcaaaac cagacgataa
     7501 attaaaaacg aacaaagaag cagcaataat aagacggcgt ttcaacagca aaccctcagg
     7561 tgtttcaaat agctgttctt tttacggaaa tacttatgaa ctggctggaa taaagtgcaa
     7621 gaaaatgtga ctactatctc atttttatct gacatgatct gttgccactc gctgccaaat
     7681 tgtcgcgcta aagctgatta gcacggtgat atttgatact ctggcagaca gcagaaataa
     7741 cggatttaac ctaatgatga atgacggtaa gcaacaatct acctttttgt ttcacgatta
     7801 cgaaaccttt ggaacgcacc ccgcgttaga tcgccctgca cagttcgcag ccattcgcac
     7861 tgataacgaa ttcaatgtca tcggcgaacc cgaagtcttt tactgcaagc ccgcggatga
     7921 ctatttaccc cagcctggag cagtattaat taccggtatt accccgcagg aggcacgggc
     7981 gaaaggagaa aacgaagccg cgtttgccgc ccgtattcac tcgcttttta ccgtaccgaa
     8041 gacctgtatt ctgggctaca acaatgtgcg tttcgacgac gaagtcacac gcaacgtttt
     8101 ttatcgtaat ttctacgatc cttacgcctg gagctggcag catgataact cgcgctggga
     8161 tttactggat gttatgcgtg cctgttatgc cctgcgcccg gaaggaataa actggcctga
     8221 aaatgatgac ggtctaccga gctttcgcct tgagcattta accaaagcga atggtattga
     8281 acatagcaac gcccacgatg cgatggctga tgtgtacgcc actattgcga tggcgaaact
     8341 ggtaaaaacg cgtcagccac gcctgtttga ttatctcttt acccatcgta ataaacacaa
     8401 actgatggcg ttgattgatg ttccgcagat gaaaccccta gttcacgttt ccggaatgtt
     8461 tggggcatgg cgtggcaata ccagctgggt ggcaccgctg gcgtggcatc ctgaaaatcg
     8521 caatgccgta attttggtgg atttggcagg agacatttcg ccattactgg agctggatag
     8581 cgacacattg cgcgagcgtt tatataccgc aaaagccgat cttggcgata acgccgccgt
     8641 tccggttaag ctggtgcata tcaataaatg tccggtactg gcccaggcga atacgctacg
     8701 cccggaagat gccgaccgac tgggaattaa tcgtcagcat tgcctcgata acctaaaaat
     8761 tctgcgtgaa aatccgcaag tgcgtgaaaa agtggtggcg atattcgcgg aagccgaacc
     8821 gtttacacct tcagataacg tggatgcaca gctttataat ggctttttca gtgacgccga
     8881 tcgtgcagca atgaaaattg tgctggaaac cgagccgcgt aatttaccgg cactggatat
     8941 cacttttgtt gataaacgaa ttgaaaaact gttgttcaat tatcgagcgc gcaacttccc
     9001 ggggacgctg gattatgccg agcagcaacg ctggctggag caccgccgcc aggtcttcac
     9061 gccagagttt ttgcagggct atgctgatga attgcagatg ctggcacaac agtatgccga
     9121 tgacaaagag aaagtggcgc tgttaaaagc gctttggcag tacgcggaag agatcgtctg
     9181 aaaataaata tcctccggca tagccggagg tttttcaaat gcgcctttaa ggctctctta
     9241 ccagccgcgc cctaacaggc gcacacgatc tgacatttgc atccaacttc gttacttacg
     9301 gcccgtaaac gggctgcccg gatagggaat cgataactgc tctcccattt tatcctcttc
     9361 aagctggtgc tttatgtaat cctgtatctt cgccgtgttc ttacccaccg tatcgacgta
     9421 ataccctctg caccagaact ccctgttcct gtatttgaat ttcaaatcac caaactgctc
     9481 gtaaggcatc agactgcttt tccctttcag atatcccata aagcctgata cgctcatttt
     9541 gggcgggatc tccacaagca tatggatatg atctgcacag cattcagctt ccagaatccg
     9601 tacacttttc cactcacaca gctttctcaa aatacagcct attgctctac acttctctct
     9661 gtagaacacc tgtcttcggt attttggcgc aaatactatg tgatatttac agttccatcg
     9721 ggtgtgcgct aagctctttt cgttccccat tgggaccccc ttttgatttc ttgtttgaca
     9781 cttgcagttg ccagaccgca aggtgtttta acaaatcaaa aggggtttta ataactggct
     9841 caaagctgaa agctttccgg aacccccagc ctagctgggg gttttctgtg cacaacaaaa
     9901 aagccggagc gacaaactcc ggctttttga gatttaccgg atgattatgt catccggttt
     9961 gtaagattac gctacgtctt cgtactgcgg aaccgggtta cggaaactct tggttacgca
    10021 agccaggtaa atcagaccga tagcagccca gatcagaccc agaaccattg agctttcttc
    10081 caggttaacc cacagcgcac caacggtcag cgcaccacac atcggcagga acagatactg
    10141 gaagtgatct ttcagcgttt tgttacgctt ctcacggatc cagaactgcg agatgaccga
    10201 caggttaacg aaggtgaacg ccaccaacgc accaaagtta atcagcgccg tagccattac
    10261 caggtcgaag ttgattgcca gcagggcaat cgcgccaacc aggatgatat tcatcgccgg
    10321 agtacgccat ttcgggtgta cataaccgaa gaagcttttc gggaacacgc cgtcacgacc
    10381 cattacgtac atcagacgcg caacgcctgc gtgcgccgcc ataccggacg ccagtacggt
    10441 aatggtggag aagatcagcg cgccaacctg gaacgcttta cccgcaacgt acagcatgat
    10501 ttcaggctgt gacgcatccg gatctttaaa acgagagata tccgggaagt acagctgcag
    10561 gaagtaagtt gcaaagatga agatcatgcc gccgatcagc gcggtcagga aaatcgcacg
    10621 cgggatcacg cgctctgcat ctttggtttc ttccgacagg ttgctgatgc cgtcaaaacc
    10681 ggtaaaggag aagcacagga ttgtcgcccc ggtaatcatc gggataacat gcgcatcgcc
    10741 agaccagaac ggacgagtgc tcgccagcgt accagcgcct tcaccttcaa atacgccata
    10801 aacaaccatg cccagaatca ccgcgatcag cactatctgc aacacgacga ttacagtgtt
    10861 gaagttcgct acggatttca gactacgcag gttaaaggcg gtcataaagg ccaccagagc
    10921 caccacaaac atccacgatg gaatggaagg caccagagct tcaaaataga ttttcgccag
    10981 cagaatgttg atcatcggcg cgaacagata gtcgagcaga gaagaccaac ccaccataaa
    11041 gccgacagtc gggctaatgg atttctgggc gtaagtgtat gcagagccag cagaaggata
    11101 gcggcgaacc agcttcccgt agctcagagc cgtaaacagg atcgcaatca atgcgaacgc
    11161 ataggctgtc ggcacatgac catccgtgag gcctgaaacg ataccaaatg tatcaaacag
    11221 cgtcatcggc tgcatatagg ctagacccat cattacaacc ggaactaacg taagcgtttt
    11281 acgcaattcc acgcgagagg tgtttggagt aacgttatgc gacatggtca ttctccttta
    11341 cggtgataac cgtcgcgtaa gcaaaaaatt gccccatttt tttggattcc tcagcgacaa
    11401 caactgtcga tttttagtaa atatctatcc ggtacgaagc ccggcctctt ggtatgaatg
    11461 attggtttga agcaaaaaat aaccgacgct aattaaacgt cggtttttag tcattttttg
    11521 acagcggcgc attgtgccta aatggggggg aaatgacaag agaatgagag gcttgccata
    11581 ataatttttc tttaaatggc tgattttccg tcatcagatt ttgcataaac accggcgatc
    11641 gcactatttg ctaaaatttc atctcgccac cagccgctgg caagccctgc ggtctgttca
    11701 ttccagccaa tccagacggg ttcaaagaga gtttgggcga ccactttctt ctcgattaac
    11761 gcgccactat cgagaaaacg ttgcgccaga taccgtggta aatagccgca gccaaggccg
    11821 ctaatttgca gctccagctt ggttttaaaa tcgaaaacgg taatggcttc ttgttcgtcg
    11881 agaagttgtg aggccgtaga agcgcctgcc tgcgcagtgt cccccaccac aatcgcccga
    11941 tatcgtttaa tgatacgacg gtttaacggt tcttcttcct gggctaacgg atgatgaggc
    12001 gcgaccgcaa agacttgttc aagatcgccc aaccgcgaga aaccaaactc actggaagat
    12061 ggtggctcat gcatcgcgcc aacgataata tccgctcgcc cctgagtcag ggcatcccag
    12121 gaaccaccga gtacgccatt gataaacttc aggcgcgtca cgctatgatg ttgataaaaa
    12181 gcttcaatga gaggcgcaag cagagaaaaa ggaaacgtgt cgtccacgcc aatcaccagc
    12241 tcgttttccc agccttcatg cagtttgatc gcctgctttt ccagttctcg cacggtatgc
    12301 agaacttccc gccctttctc taataacatt tttccggtac gggtgaattt agcgcggtgt
    12361 ccgctacgat caagcaattg aatattaagg tcgctttcca gcttgtgaac ggtgtaactc
    12421 agagcggacg gcgtcttgta gagtttggct gacgccgccg caaaactgcc ttctttttct
    12481 aaggcatcga ggatcatcaa cacatccagc agtggtttca tacacgcccc cttgcagtgc
    12541 atgcggcgtc ctgctggcgt gatcgtttac tccagcggca ttaccagcgg atcgggatac
    12601 tggtattcaa atcccagttc attacaaatc cgactgccat caataatctt acctttgccg
    12661 ctgtccagac tatttctgaa ctgcggaggt tccagcccca gtaaacgggc catctgcgga
    12721 tagaaaacat tacgcgcagg gtgagctggc gcacatatat tatagatgtg tccgccttta
    12781 ggtgcctgta acaacagagt gatagcgcca ataacatctt ctaaatggac taaattaaca
    12841 ccatgttcac catcaggggc ggtttttccg gcaaagaagc gtccgggatg acgtcccggt
    12901 ccgaccaggc ccgcaagacg cagaatatcg accgaagtac cgggtaaatt gtgcagccag
    12961 tcttcgagtt cttctaatac tcgtccactg ttggttaccg gattacgcgg ggtggtttct
    13021 ttcaccgtgc cttgtgcgtc gccatagaca gacgtcgagc tggtaaaaat aatacgggga
    13081 atacgatgag ccagcgcgct atccactaac tcttgtaccg cttgtaaata gaactcatcg
    13141 ccggggccgc tacgacgtgc cggaagcgta atgaccagcg catcggcatc cataagggca
    13201 tccagatcgt cagaatcgca aactaactca ggctccatgc gaagcagata gctatcaatg
    13261 ccactcattc gggccgcttc gacaccatct tgtgtggttt tactcccggt gacttgccag
    13321 cctcgcgctg aaagtgacat cgccagcggc atacctaacc accctaaccc gacaattgcg
    13381 acctttttca tccgttatct cctgatacac cttagatcta taaggctacg ctagcgtatc
    13441 aaaactgaca attcattcta tgaatgaatc tcttcaataa tgataacgac atgctgcaat
    13501 gagcagtgaa tcatcagtaa ccgcgtatac cagaaggtgc tcctctgtaa tgcgtcggga
    13561 ccagaaacct gacaagttat gtttcagggg ttctggtttc cccttacctt caaatggtgt
    13621 tctgcgggta tctttgataa gttcattgat ctttttaaca attcgcttat ctgcttcctg
    13681 ccagtacaga taatcatccc atgattcctc agaccagatt agtttcactc aataatgtcc
    13741 ttttccgttc ctttgtctga tttcaggcta tcgattgagt ccatcaatct ccgggcgtta
    13801 gcgggggaac gcagtagata agccgtctct tccagcgagt tgtattcttc gagtgacatc
    13861 agaacacaag cctctccatt ctgacgagta atgaggatcg gggcatgatc ttcaacggct
    13921 ttcatcattg ttgccgacaa attctgacgc gcttcgctgt agctaattgt acgcatgtaa
    13981 atctcctctt ttgtacagtt cattgtacaa tgatgggtgt taattaacta tttattaatt
    14041 agtttgtaga tcaagacatt gccagcgaga cgaaaaatca gactttgctc tttttggtgc
    14101 tgtcaagtta gaggacagtc ctcttagccc ccttctttcc ccgctcattc attaaacaaa
    14161 tctatcgcca taaaatatat aaaaaagccc ttgctttcta acgtgaaagt ggtttaggtt
    14221 aaaagacatc agttgaataa acattcacag agacttttat gacacgcgtt caatttaaac
    14281 accaccatca tcaccatcat cctgactagt ctttcaggcg atgtgtgctg gaagacattc
    14341 agatcttcca gtggcgcatg aacgcatgag aaagcccccg gaagatcacc ttccgggggc
    14401 ttttttattg cacgattgat aacggttcag acaggtttaa agaggaataa gaaaatgaca
    14461 gacaacactc gtttacgcat agctatgcag aaatccggcc gtttaagtga tgactcacgc
    14521 gaattactgg cgcgctgtgg cattaaaatc aatcttcaca cccagcgtct gatcgcgatg
    14581 gcagaaaaca tgccgattga tattctgcgc gtgcgtgacg acgatattcc cggtctggta
    14641 atggacggcg tggtagacct tgggattatt ggcgaaaacg tgctggaaga agagctgctt
    14701 aaccgccgcg cccagggtga agatccgcgc tactttaccc tgcgtcgtct ggatttcggc
    14761 ggctgccgcc tttcgctggc aacgccggtt gatgaagcct gggacggtcc gctctcctta
    14821 aacggtaaac gtatcgccac ctcttatcct cacctgctca agcgttatct cgaccagaaa
    14881 ggtatctctt ttaaatcctg cttactgaac ggttctgtcg aagttgcgcc gcgtgccggg
    14941 ctggcggatg cgatttgcga tctggtttcc accggtgcca cgctggaagc taacggcctg
    15001 cgcgaagtcg aagttatcta ccgctcgaaa gcctgcctga tccagcgcga tggcgaaatg
    15061 gaagaatcca aacagcaact gatcgacaaa ctgctgaccc gtattcaggg tgtgatccag
    15121 gcgcgcgaat caaaatacat catgatgcac gcaccgaccg aacgcctgga tgaagtcatc
    15181 gccctgctgc caggtgccga acgcccaacc attctgccgc tggcgggtga ccaacagcgc
    15241 gtagcgatgc acatggtgag tagcgaaacc ctgttctggg aaacgatgga aaaactgaaa
    15301 gcgctgggtg ccagttcaat cctggtcctg ccgattgaga agatgatgga gtgatcgcca
    15361 tgagctttaa cacaatcatt gactggaata gctgtactgc ggagcaacaa cgccagctgt
    15421 taatgcgccc ggcgatctcc gcttctgaaa gcattacccg caccgttaac gatattctcg
    15481 ataacgtgaa aacgcgtggc gatgaggccc tgcgtgaata cagcgcgaag tttgataaaa
    15541 ccacggttac cgcgctgaag gtgtctgctg atgagatcgc cgccgccagc gaacgcctga
    15601 gcgacgagct aaaacaggcg atggcggtgg cagtaaagaa tattgaaacc ttccacactg
    15661 cgcaaaaact gccgccggta gatgtagaaa cgcagccagg cgtgcgttgc cagcaggtca
    15721 cgcgcccggt ggcttcagtg ggtttgtata ttcctggcgg ctccgccccg ctcttctcaa
    15781 cggtattaat gctggcgact ccggcgcgta ttgcgggctg taaaaaagtg gtgctgtgct
    15841 caccgccgcc gattgccgat gagatccttt atgcggcgca actgtgcggt gtgcaggacg
    15901 tgtttaacgt cggcggcgca caggccattg ccgcgctggc gtttggtacg gaatctgtgc
    15961 cgaaagtgga caaaatcttc gggccgggta acgcctttgt caccgaagca aaacgccagg
    16021 taagccagcg tctggacggt gcggcgatcg atatgcccgc aggcccgtcg gaagtgctgg
    16081 tgattgctga cagcggcgca acgccggatt tcgtggcttc tgatttgctc tcccaggctg
    16141 aacacggccc ggactcacag gtgattttac tgacacctga tgctgatatg gcgcgtcgcg
    16201 ttgccgaggc cgtcgaacgc cagttggcag aattgccgag agctgaaacc gcccgtcagg
    16261 cactgagcgc cagccgcctg atcgtaacca acgatttagc gcagtgcgta gagatctcca
    16321 atcagtacgg tccggagcac ctgatcattc agacccgcaa cgcccgcgat ctcgtcgata
    16381 gcattaccag cgccggttcg gtatttctcg gtgactggtc accggaatcg gcaggtgatt
    16441 acgcctccgg caccaaccac gtgctgccga cttacggtta caccgccacc tgttccagcc
    16501 tcgggctggc agatttccag aaacgcatga ccgtacagga actgtcgaaa gaaggtttct
    16561 ccgcgctggc ttcgaccatt gaaacactgg ccgccgccga gcgcctgacc gcccacaaaa
    16621 atgccgttac tttgcgtgtt aacgtcctta aggagcaagc atgagcaccg tgactattac
    16681 tgatttagcg cgtgaaaacg tccgcaacct gacgccgtat cagtcggcgc gtcgtctggg
    16741 cggtaacggc gacgtctggc tgaacgccaa cgaatatccc acagccgtgg agtttcagct
    16801 tactcagcaa acgctcaacc gctacccgga atgccagcca aaagcggtga ttgaaaatta
    16861 cgcgcaatat gcaggcgtaa aaccggaaca ggtgctggtc agccgtggcg cggacgaagg
    16921 tattgaactg ctgatccgcg ctttttgcga accgggtaaa gacgccatcc tctactgccc
    16981 gccaacgtac ggcatgtaca gcgtcagcgc tgaaaccatt ggcgtcgaat gccgcacagt
    17041 gccgacgctg gaaaactggc aactggactt acagggcatt tccgacaagc tggacggcgt
    17101 aaaagtggtc tatgtttgca gccccaacaa ccccaccggg caactgatca acccacagga
    17161 ttttcgcacc ctgctggagt taacccgcgg taaggcgatt gtggttgccg atgaagccta
    17221 tatcgagttt tgcccgcagg catcgctggc tggctggctg gcggaatatc cgcacctggc
    17281 tattttgcgc acactgtcga aagcttttgc tctggcgggg cttcgttgcg gatttacgct
    17341 ggcaaacgaa gaagtcatca acctgctgat gaaagtgatc gccccctacc cgctctcgac
    17401 gccagttgcc gacattgccg cacaggcgtt aagcccgcag ggaatcgtcg ccatgcgcga
    17461 acgggtggcg caaattattg cagaacgcga atacctgatt gccgcactga aagagatccc
    17521 ctgcgtggag caggttttcg actctgaaac caactacatt ctggcgcgct ttaaagcctc
    17581 cagtgcagtg tttaaatctt tgtgggatca gggcattatc ttacgtgatc agaataaaca
    17641 accctcttta agcggctgcc tgcgaattac cgtcggaacc cgtgaagaaa gccagcgcgt
    17701 cattgacgcc ttacgtgcgg agcaagtttg atgagtcaga agtatctttt tatcgatcgc
    17761 gatggaaccc tgattagcga accgccgagt gattttcagg tggaccgttt tgacaaactc
    17821 gcctttgaac ctggcgtgat cccggagctg ctgaagctgc aaaaagcggg ctataagctg
    17881 gtgatgatca ccaatcagga tggtctggga gcacaaagtt tcccgcaggc ggatttcgat
    17941 ggcccgcaca acctgatgat gcagatcttc acctcgcaag gcgtgcagtt tgatgaagtg
    18001 ctgatttgcc cacacctgcc cgccgatgag tgcgactgcc gtaagccgaa agtaaaactg
    18061 gtggagcgtt atctggctga gcaagcgatg gatcgcgcta acagttatgt gattggcgat
    18121 cgcgcgaccg acattcaact ggcggaaaac atgggcatta atggtttacg ctacgaccgc
    18181 gaagccctga actggccaat gattggcgag caactcacta aacgagaccg ttacgcccat
    18241 gtagtgcgca acaccaaaga gacgcaaatt gacgtccagg tgtggctgga tcgcgagggt
    18301 ggcagcaaga ttaacaccgg cgttggcttc tttgatcaca tgctggatca gatcgccacc
    18361 cacggcggtt tccgtatgga aatcaacgtt aaaggcgacc tctatatcga cgatcatcac
    18421 accgtcgaag ataccggcct ggcgctgggg gaagcattaa aaattgctct tggcgacaaa
    18481 cgcggtattt gccggtttgg ttttgtgctg ccgatggacg aatgccttgc ccgctgcgca
    18541 ctggatatct ctggtcgccc gcacctggaa tataaagccg agtttaccta ccagcgtgtg
    18601 ggcgatctca gcaccgagat gatcgagcac ttcttccgtt cgctctcata caccatgggc
    18661 gtgacgctac acctgaaaac caaaggtaaa aacgatcacc accgtgtaga gagcctgttc
    18721 aaagcgtttg gccgcaccct gcgccaggcc atccgcgtgg aaggcgacac cctgccctcg
    18781 tcgaaaggag tgctgtaatg aacgtggtga tccttgatac tggctgcgcc aacctgaact
    18841 cggtgaagtc tgccattgcg cgtcacggtt atgaacccaa agtcagccgt gacccggacg
    18901 tcgtgttgct ggccgataaa ctgtttttac ccggcgttgg caccgcacaa gcggcgatgg
    18961 accaggtgcg cgagcgcgag ctgtttgatc tcatcaaagc ctgtacccaa ccggtgctgg
    19021 gcatctgctt agggatgcaa ctgctggggc ggcgcagcga agagagcaac ggcgtcgact
    19081 tgctgggcat catcgaagaa gacgtgccga aaatgaccga ctttggtctg ccactgccac
    19141 atatgggctg gaaccgcgtt tacccgcagg caggcaaccg cctgtttcag gggattgaag
    19201 acggcgcgta cttttacttt gttcacagct acgcaatgcc agtcaatccg tggaccatcg
    19261 cccagtgtaa ttacggcgaa ccgttcaccg cggcggtaca aaaagataac ttctacggcg
    19321 tgcagttcca cccggagcgt tctggtaccg ctggcgctaa gttgctgaaa aacttcctgg
    19381 agatgtgatg attattccgg cattagattt aatcgacggc accgtggtgc gtctccatca
    19441 gggcgattat ggcaaacagc gcgattacgg taacgacccg ctgccgcgct tacaggatta
    19501 cgccgcacaa ggtgccgaag tactgcacct ggtggatctg accggggcaa aagatccggc
    19561 taaacgtcaa atcccgctga ttaaaaccct ggtcacgggc gttaacgtcc cggtgcaggt
    19621 tggcggcggc gtgcgtagcg aagaagacgt ggcggcgtta ctggaagcag gcgttgcgcg
    19681 tgtggtggtt ggctccaccg cggtgaaatc accagaaatg gtgaagggct ggtttgaacg
    19741 ttttggtgcc gatgccttag tgctggcgct ggatgtccgt atcgacgagc aaggcaacaa
    19801 gcaggtggca gtcagcggct ggcaagagaa ctcgggcgtt tcactggaac aactggtgga
    19861 aacctatctg cccgtcggcc tgaaacatgt gctgtgtacc gatatctcgc gcgacggcac
    19921 gctggcggga tctaacgtct ttttatatga agaagtgtgt gccagatatc cgcaagtggc
    19981 gtttcagtcc tccggcggca ttggcgatat taacgatgtg gcggccctgc gtggtactgg
    20041 tgtgcgcggc gtaatagttg gtcgtgcatt actggaaggt aaattcaccg tgaaggaggc
    20101 catcgcatgc tggcaaaacg cataatcccg tgtctcgacg ttcgtgatgg tcaggtggtg
    20161 aaaggcgtac agtttcgcaa ccatgaaatc attggcgata tcgtgccact ggcaaaacgc
    20221 tacgccgaag aaggtgcaga tgaactggtg ttctacgata tcaccgcttc cagcgatggc
    20281 cgtgtggtag ataaaagctg ggtatctcgc gtggcggaag taatcgacat tccgttttgt
    20341 gtggcgggtg ggattaagtc tctggaagat gccgcgaaaa ttctttcctt tggcgcagat
    20401 aaaatctcca tcaactctcc tgcgctggcg gacccgacgt taattactcg cctggccgat
    20461 cgctttggcg tgcagtgtat tgtggtcggt attgatacct ggtacgacgc cgaaaccggt
    20521 aaatatcatg tgaatcaata taccggcgat gaaagccgca cccgcgttac tcagtgggaa
    20581 acgctcgact gggtacagga agtgcaaaaa cgcggtgccg gagaaatcgt cctcaacatg
    20641 atgaatcagg acggcgtgcg taacggttac gacctcgagc agctgaaaaa agtgcgtgaa
    20701 gtttgccacg tcccgctgat tgcctccggt ggcgcgggca ccatggaaca ctttctcgaa
    20761 gccttccgcg atgccgacgt tgacggcgcg ctggcagctt ccgtattcca caaacaaata
    20821 atcaatattg gtgaattaaa agcgtacctg gcaacacagg gcgtggagat caggatatgt
    20881 taacagaaca acaacgtcgc gaactggact gggaaaaaac cgacggtctg atgccggtga
    20941 ttgtgcaaca cgcggtatcc ggcgaagtgc taatgctggg ctatatgaac ccggaagcct
    21001 tagacaaaac cctcgaaagc ggcaaagtca ccttcttctc gcgcactaaa cagcgactgt
    21061 ggaccaaagg cgaaacgtcg ggcaatattc tcaatgtggt gagtattgcc ccggactgcg
    21121 acaacgacac gttactggtg ctggcaaatc ccatcggccc gacctgccac aaaggcacca
    21181 gcagctgctt cggcgacacc gctcaccagt ggctgttcct ttatcaactg gaacaactgc
    21241 tcgccgaacg taaatctgcc gacccggaaa cctcctacac cgccaaactg tatgccagcg
    21301 gcactaaacg cattgcgcag aaagtgggcg aagaaggcgt ggaaaccgca ctggcagcaa
    21361 cggtacatga ccgctttgag ctgaccaacg aggcatctga cttgatgtat cacctgctgg
    21421 tgttgttgca ggatcaggat ctggatttag cgacggtaat tgagaacctg cgtaaacggc
    21481 atcagtgagt tgcgtgctga ccggatgcga tgttgttgtc gcatccggag ccattgcccg
    21541 atgcgcaagc ttatcgtgcc tacacattat ctcaacacac gtaggccgga taagatgcgc
    21601 cagcatcgca tccggcaaaa aaaacgggca tggtgtcacc accctgcccg tttctcttaa
    21661 atgcacaata atattatttc gcgttgtaat tacgcagcgc gttacgcccc aacacaatcc
    21721 ccacgccaac catgccgccc agcagcaccg ccagaatcaa ggtaattgcc tttttcgggc
    21781 tatcgcgacg aataggtaac gtcggtttca ttacatagcg gtaagcatga atatcaagtt
    21841 tatcaacgtc aagattgtcg atatccagca ggttttgacg agtctgatag tagcttgatg
    21901 agaacaccaa cggacgggtc gcctcgtgct taatcatcga ctccagcgct tcgctcccca
    21961 aaaggaacat agtatcctgg gttacgtcct gcgtctgttg aatctgcggc tttgtcacct
    22021 gcgcctgatt cgcatactgc aacgcttcct gaatctgacg gatacgcaga tctttctgtt
    22081 cctgcgcgac cacttcctgg gttcttaaag agtcctgcaa gtttttccgt cccagagcaa
    22141 tgttgtcctt gagatccttt tctagctctt gattcacttt atcatcaact tgctgaatgt
    22201 attgggccaa cttcatttgt gcgccctctg cagtttgccc aacataagaa acagtcaatg
    22261 gtaattgctg gttcttaaca gaaggttcga tggtaagttt ttctggctct tcctgattat
    22321 ccagcgtttc tgctaatgca gagaaggcag aactgaagcg accaattaac gtctcctgca
    22381 aatccgatac tttcggtgta gcctgaccat agataacatt catggcattg ttatagccag
    22441 caatttgccc cacgtcgggc tgagtgataa ttgctgttga cgtccatttc tccttcgcta
    22501 ctgccaaata accaatagcc agggcaatag ccacaatgac ggaaatgatg attgtcatct
    22561 tgccacgcca caactgcact agtaaatcaa tcaaatcaat ctgttccggg tcatggtttt
    22621 gcccagaaac attattattt tctactctca tcattaccct aactgacgga aatttccaag
    22681 tccgcatagt ttagcgataa tcctcgtgaa tgctatagga taagtgataa aaataatgaa
    22741 ttgttgagga agtaacaaaa gacaatcagg gcgtaaatag ccctgataac aagatgttaa
    22801 tcgctaccaa agagatcgcg ggtgtatacc ttatctgcca catccttaag ctcttctgcc
    22861 atacgattgg agataatgac atcagcttgt tgtttgaaag tggcgagatc tcgttccagg
    22921 cgagagttga agaatgagtc ttctttcatc accggttcgt aaatgatcac ttcaacgcct
    22981 ttcgccttga tacgtttcat aatcccctga atggaagacg cgcggaagtt gtctgaaccg
    23041 ctcttcataa tcagacgata aatacccacc acttgcggct tgcgtgacaa aatggcatcg
    23101 gcaataaaat ctttacgcgt gcggttagca tcgacaattg ccgaaatcag gttattcggc
    23161 acagactgat aattcgccaa taactgtttg gtatctttcg gcaaacaata accaccataa
    23221 ccaaacgacg gattgttgta atggttgccg atacgcgggt cgagacaaac accttcgata
    23281 atctgacgcg tattcagacc caaactttct gcatagctat ccagttcgtt aaagtacgcc
    23341 acgcgcatcg ccagataggt attagcgaaa agtttaatcg cttctgcttc agtggagtcg
    23401 gtaaacaggg tcgggatatt ttgcttaatc gtgccttcct gtaacaacgc agcaaaacgt
    23461 tctgcgcgtt ctgaacgctc accgatgaca atacgtgacg gatgaaggtt atcgtaaagg
    23521 gctttaccct cacggagaaa ttccggggag aatataatat tttcagtacg atatttttta
    23581 tgcatcgctg cggtaaaacc aacgggaacc gttgatttga tgaccataac cgcataaggg
    23641 tttatctcaa ctacgtcttt aattactgat tctacactgg atgtattgaa ataattagtt
    23701 ttaggatcat agtcggttgg agtggcgatg atgacataat cagcatcccg gtaggcttca
    23761 tttttatcta atgtggcatt aaagtgtatt ttatctgatt gcaaaaactg ctgaatttcc
    23821 ttatcaacaa taggagatat ccgatcattc agcatagcaa cgcgtgacgg taaaatatct
    23881 aatgccacaa cctcatgatt ttgtgcgatt agaagcccgt ttgacaagcc tacatagcca
    23941 gtaccggaaa tggtaatttt catttcatgc tctcagaatt aacttaactg tgaatcatga
    24001 tgtttttagc atcctgacaa gagttaaaag ttttaacgct acgtcgatag ctggtcaacg
    24061 caacgaaaaa caattcagaa tttctttata agaatagctg atatttatta agttaatatt
    24121 aagcagtgaa atttagtcta taagataaat ggcaaaaaaa gcccggcaca atatacgccg
    24181 ggcctcaatt tattgttagt taagtcagat taatccagcc attcggtatg gaacacacct
    24241 tctttatcga tgcgcttata agtatgtgca ccgaaatagt cacgctgtgc ctggatcagg
    24301 tttgcaggca gaacagcggc acggtagctg tcataatagg caaccgcagc ggcgaaggtc
    24361 ggaaccggga taccgttctg tactgcataa gcaacgacat cgcgcagcgc ctgctgatag
    24421 tcatcggcga tttgcttaaa gtacggagcc agcagcaggt tagcgatctg cggattttcg
    24481 gcgtatgcat cggtgatttt ctgcaggaac tgcgcacgga tgatgcagcc agcacggaaa
    24541 atcttcgcga tttcgccgta gttcagatcc cagttgtatt cttcagacgc agcacgcaac
    24601 tgagagaagc cctgagcgta agaaacgatt ttgcccagat acagcgcacg acgaaccttc
    24661 tcgataaact cagctttgtc gcctgctcgc tgcgcttgcg ggccagagag aactttagac
    24721 gcggcaacgc gctgatcttt cagagaagag atataacgtg caaacacaga ctcggtaatc
    24781 agcgacagcg gttcgccgag atccagcgcg ctctggctgg tccatttacc cgtacctttg
    24841 tttgcagctt catccagaat cacatcaacc aggtagttac cgtcttcatc ttttttggtg
    24901 aagatatctt tggtaatgtc aatcaggtag ctgctcagtt caccgttatt ccactcggta
    24961 aaggtctgcg ccagttcttc gttggtgagg ttcaggccac ctttaagcag agaataggct
    25021 tcagcaatca gctgcatatc accgtattca ataccgttgt gaaccatctt cacatagtgg
    25081 cctgcgccat cggcaccaat ataggtaacg catggctccc cgtcttcagc cactgcggcg
    25141 attttggtca ggatcggcgc aaccagttca taggcttctt tctggccacc aggcataatg
    25201 gaaggtcctt tcagcgcgcc ttcttcaccg ccagaaacac cagtaccgat gaagttaaag
    25261 ccttctgcag aaagctcacg attacgacga atagtgtcct ggaagaaggt gttaccacca
    25321 tcaatgatga tgtcaccttt atcgaggtac ggcttaaggg aatcaatagc agcatccgtg
    25381 cctgcacctg ctttcaccat taacaggatg cgacgaggcg tttccagaga ttcaacaaac
    25441 tctttcaccg tatagtaagg aaccagtttt ttgcctggat tttcggcaat cacttcttcc
    25501 gttttttcac gggaacggtt gaaaatagag acggtataac cacggctttc gatgttgagc
    25561 gcaaggttgc gccccatcac tgccataccg acgacgccga tctgttgctt tgacattgtt
    25621 tactcctgtc agggcgttaa aaaat
//
LOCUS       DAPOXO010000076        25461 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPOXO010000076 DAPOXO010000000
VERSION     DAPOXO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25461
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.076"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            29..595
                     /locus_tag="ROH59_003692"
     CDS             29..595
                     /locus_tag="ROH59_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX4806128.1"
                     /translation="MNKKLLSLLVSGSLIAVVSTSVFATDTGVVNFNGKIVADTCEIN
                     VNESASTTGTVTFADTYPADYSGDGSIGTSKDFKIELIKCDPLVDKLNLTFSGTTTDA
                     GFLRLENSEAGAGSATNVGITVTNKNGGANDVKFDGSVPDASTDVDNAGSITPTIFNY
                     TANVIQVGNNAPTAGKYASSATFEVFYR"
     gene            641..1357
                     /locus_tag="ROH59_003693"
     CDS             641..1357
                     /locus_tag="ROH59_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX4806129.1"
                     /translation="MSVFSRVCLGFTFLLTALQVQASIVLGGTRIIYPSNQNEVQITL
                     KNKDAYARYLVQSWVSNIDGSKAPFLITPPVYKLEENRQTLLHIVFTGDKNKLPQDRE
                     SLFLANIKSVSAMPEELKDRNTLQFAMKARLKLFWRPASLDNSDALTAWEKLKFHKEA
                     GKLIVKNPTPFYISFSDLTVSGKNIVPTESKSEPGALLMMVGPFSEQRFSLPVGAGSI
                     VEWSVITDYGSSSGKRQQKL"
     gene            1424..3901
                     /locus_tag="ROH59_003694"
     CDS             1424..3901
                     /locus_tag="ROH59_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX4806130.1"
                     /translation="MLLPLHRTFVLTGITFALSAVYSLSYARDEFNLRILELDSPLEN
                     TQVLEDFVNNNNLTPGVYLTSVMWGQEYLDKRNITFILSSDKKRLIPRFTKADLREFG
                     LKVDDIPALQVMDDDTEFGDIAQIIDGARYDFQLDSQTLCLRIPQIYQNARAAGSISP
                     KYWSDGESAVWLSYYASGSRQNSDGDNLNSNWLNLNSGINLGVWRLRNNTVYSDSSWE
                     SISTSLQRDIKALRSQMEVGQTFTNGDLFDSVQMTGIKLETDTSMLPDSEQGFAPVVR
                     GIANSDAQVVIKQNGYVIYQTWVSAGPFEIKDLSQVTAGADLEVTIKETNGQEHSFIQ
                     ASSTVPILQREGALKYSLATGKYRDNDNHAETPVFGVATAIYGLPYGITIYGGILGAS
                     IYHSGVTGIGADLGRLGSVSVDITAAETKFDDGRDDATGLSWRAQYAKDFPDTDTTVT
                     LASYRYSTSQFYTFQEALDQRDTPDDKGIYSYRQTNNRRNRLQINLSQNIGRWGSVYL
                     NGYQQDYWGMHGAERSIGMGYSTTWSNINWSVNYTLTKTPGMAGEQQFSLTLNIPLSR
                     WLPDSWAMYNVNRSDKSNTSHQLGIGGTALQDNNLSYNLQQSYTDNNVGYDASMNGRY
                     RSSVGEFGLGYSYDKNSRQWNYSAQGAVVAHAHGVTLGQSVQDSFAIVHINEGANVKV
                     QNAQGVYTDYWGNAIVPNMTNYRHNAITVNTQGHDSLDISDATQDVIPSKGAVVGVDF
                     DARSGIRALLTLVHNKERVPFGALLTLGNSTAIVGEDGEVYITGVQESMTFTVQWGKE
                     INQQCTGVVTVPEKYTTGIYKATMDCR"
     gene            3923..4933
                     /locus_tag="ROH59_003695"
     CDS             3923..4933
                     /locus_tag="ROH59_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX4806131.1"
                     /translation="MKPGFVSYIRTLLTIIFLSWGVIPEVFAGCNISGNGGNPATVQF
                     SVPALVVNSDAVPGTIIATVNANSPSISVSCTANGEIWQGYTVLTNGDMRTDNPLNNV
                     FQTNVPGIGFRAAWANNTSAQLTAGYLMTPWHKGSSTVIKGYGYPITIHAAIQFIVTG
                     PVGNGTIDTSKLVADWKYDNRVIGELRFSSVPVNIQPGTCDLIEKNITVPLNDIGTDD
                     FDVNNVSPVVSDDRFKIQIEKCSQDVKVDYRFTSSGSTGVTGNNILNIESGSGMAEGV
                     GLQILDSNNNVMVFDTDYTPVQKTTLNQNVTIPLKARYIKMGSVKSGRVNSVATFEVY
                     YR"
     gene            5153..7402
                     /gene="fhuA"
                     /locus_tag="ROH59_003696"
     CDS             5153..7402
                     /gene="fhuA"
                     /locus_tag="ROH59_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HDX4806132.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVAVGTRGASNTYDYLIIRGFAADGQSQNNYLNGLKMQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALD
                     DDGVYSYRLTGLARSANAQQKGAEEQRYAIAPAFTWRPNDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMIGYSFDHEFNDTFTVRQNLR
                     FAQNKVSQKSVYGYGMCSDPLYSSNPSSSPCANVPQSQWGHTLTRQYVIDNEKLENFS
                     VDTQLQSKFATGSVDHTLLTGVDFMRMRNDIDSWFGYAGSVAPSDIYNLDRSDFDFGA
                     HPNPSGPYRVLLKQKQTGLYVQDQAQWDKVLVTLGGRYDWADQSSFNRDYGNKSERDD
                     KEFTWRGGVNYLFDNGVTPYFSYSESFEPASQTDANGDLFAPSKGKQYEVGVKYVPED
                     RPIVVTGALYQLTKTNNLMADPNGSLFSVEGGEIRARGVELEAKAALSASVNLVGSYT
                     YTDAEYTTDTNYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPA
                     NSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQ
                     VVATATFRF"
     gene            7454..8251
                     /gene="fhuC"
                     /locus_tag="ROH59_003697"
     CDS             7454..8251
                     /gene="fhuC"
                     /locus_tag="ROH59_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HDX4806133.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILIDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGVADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            8251..9141
                     /gene="fhuD"
                     /locus_tag="ROH59_003698"
     CDS             8251..9141
                     /gene="fhuD"
                     /locus_tag="ROH59_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HDX4806134.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAVIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRILDNAIGGKA"
     gene            9138..11120
                     /gene="fhuB"
                     /locus_tag="ROH59_003699"
     CDS             9138..11120
                     /gene="fhuB"
                     /locus_tag="ROH59_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HDX4806135.1"
                     /translation="MSKRIALFPVLLLALLVVAAAALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLAISLLVGAGLGMVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVATERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPTGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     gene            complement(11155..12435)
                     /gene="hemL"
                     /locus_tag="ROH59_003700"
     CDS             complement(11155..12435)
                     /gene="hemL"
                     /locus_tag="ROH59_003700"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDX4806136.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LREAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMSCDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            12660..14081
                     /gene="clcA"
                     /locus_tag="ROH59_003701"
     CDS             12660..14081
                     /gene="clcA"
                     /locus_tag="ROH59_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HDX4806137.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            14105..14170
                     /locus_tag="ROH59_003702"
     CDS             14105..14170
                     /locus_tag="ROH59_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806138.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            14163..14507
                     /gene="erpA"
                     /locus_tag="ROH59_003703"
     CDS             14163..14507
                     /gene="erpA"
                     /locus_tag="ROH59_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HDX4806139.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(14554..15177)
                     /locus_tag="ROH59_003704"
     CDS             complement(14554..15177)
                     /locus_tag="ROH59_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HDX4806140.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(15215..16015)
                     /gene="btuF"
                     /locus_tag="ROH59_003705"
     CDS             complement(15215..16015)
                     /gene="btuF"
                     /locus_tag="ROH59_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HDX4806141.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            complement(16008..16706)
                     /gene="mtnN"
                     /locus_tag="ROH59_003706"
     CDS             complement(16008..16706)
                     /gene="mtnN"
                     /locus_tag="ROH59_003706"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDX4806142.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            16790..18307
                     /gene="dgt"
                     /locus_tag="ROH59_003707"
     CDS             16790..18307
                     /gene="dgt"
                     /locus_tag="ROH59_003707"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HDX4806143.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLETYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            18437..19861
                     /gene="degP"
                     /locus_tag="ROH59_003708"
     CDS             18437..19861
                     /gene="degP"
                     /locus_tag="ROH59_003708"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HDX4806144.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGPGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSDLAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSST
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     gene            20016..21173
                     /gene="cdaR"
                     /locus_tag="ROH59_003709"
     CDS             20016..21173
                     /gene="cdaR"
                     /locus_tag="ROH59_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HDX4806145.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     gene            complement(21227..21613)
                     /locus_tag="ROH59_003710"
     CDS             complement(21227..21613)
                     /locus_tag="ROH59_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HDX4806146.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(21923..22747)
                     /gene="dapD"
                     /locus_tag="ROH59_003711"
     CDS             complement(21923..22747)
                     /gene="dapD"
                     /locus_tag="ROH59_003711"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HDX4806147.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFANYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(22778..25450)
                     /gene="glnD"
                     /locus_tag="ROH59_003712"
     CDS             complement(22778..25450)
                     /gene="glnD"
                     /locus_tag="ROH59_003712"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HDX4806148.1"
                     /translation="MNTLPEQYANTALPTLHGQPQNPCAWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
BASE COUNT         6121 a         6083 c         6785 g         6472 t
ORIGIN      
        1 tgtattacct cataattaag ggatttttat gaataaaaaa ttgctttctc tgttagtgtc
       61 aggaagtctc atcgctgtag taagtaccag tgtatttgct acagataccg gagtggttaa
      121 ctttaacggt aaaattgttg ccgatacttg cgaaattaat gtaaacgagt ctgccagtac
      181 aacagggaca gtcacttttg cagatactta cccagcggac tattctggag acggtagtat
      241 tggaacgtca aaagatttta aaattgaatt aataaaatgc gatccgttgg tggacaaact
      301 aaacctgaca ttttctggaa cgacaacgga tgcaggtttc ctgcgtctgg aaaatagcga
      361 agctggggct ggcagtgcaa caaatgtggg tattacggtg acaaataaaa atggcggtgc
      421 taacgatgtg aaatttgatg gttcagttcc cgatgcatcc actgatgttg ataatgccgg
      481 gagcattact ccaacaatat tcaattacac cgccaatgtt attcaggttg gtaataacgc
      541 gccgactgcg ggtaagtatg cctcatctgc gacgttcgaa gtattttatc gctaatattc
      601 atagtgtttg aaaggactgt ttgaccacgg agggttattt atgtcagttt tttctcgagt
      661 ttgtttaggt tttacgtttc ttcttacggc attgcaagtt caggcaagta ttgttcttgg
      721 cggtacacgt attatctatc cttcaaatca aaatgaagtt caaatcacat taaaaaataa
      781 agatgcatat gcacgctatt tggtgcaaag ctgggtgagt aatattgatg gctctaaagc
      841 cccctttctc attacgcctc cagtttataa acttgaagaa aatcggcaaa cattactcca
      901 tattgtattt acaggtgata aaaacaaact tcctcaggat agggaaagtt tgtttctggc
      961 aaacataaaa tctgtttctg cgatgccaga agaactaaaa gatagaaata ccttgcaatt
     1021 tgcaatgaaa gcccggctta aattattttg gcggccagct tctttggata atagtgatgc
     1081 tctcactgca tgggaaaaac ttaagttcca taaagaagcg gggaagctca tagtaaaaaa
     1141 tccaacgcct ttttatattt cattcagtga tctgacagta tcgggaaaaa atattgttcc
     1201 caccgagagc aaatctgaac ctggcgcatt attgatgatg gtaggaccat tttctgagca
     1261 gcggtttagt cttcctgtcg gagcgggaag tattgttgaa tggtcggtga taactgacta
     1321 cggttcaagt tctgggaaac gacaacaaaa gttataaatc accgaagtgt attactataa
     1381 ataaccgatc tgtatttata atattacggg cgcaagggaa tttatgctgc taccattgca
     1441 tcgcacattt gtcttaactg ggataacatt tgcattatcg gcagtgtatt cattgagcta
     1501 tgcacgagat gaatttaacc ttcgtatcct ggagctggat agcccacttg aaaatacaca
     1561 agtgctggag gattttgtta ataataataa cttaactccg ggagtatatc ttacctctgt
     1621 tatgtggggg caagagtatc ttgataagag aaatattacc ttcattctgt cttcggataa
     1681 aaaaaggctc atccctcgtt ttacaaaggc ggatctccgt gagttcggtc ttaaagttga
     1741 cgacattccc gcgttacaag taatggatga tgacactgag tttggtgata ttgctcagat
     1801 tattgatggc gcacgttatg atttccagtt agacagccaa acgctgtgtc tgcggatccc
     1861 gcaaatctat cagaatgcgc gggccgcagg gagtatttca ccgaaatact ggagtgatgg
     1921 tgagagtgcg gtttggttaa gttattacgc cagtggttcc cggcaaaaca gtgatggcga
     1981 taacctgaat tcaaattggt tgaatttaaa ttcagggatt aatttaggcg tatggcggct
     2041 acgaaataat accgtttaca gtgactccag ttgggagtcg atcagcacca gtttgcaacg
     2101 cgatatcaaa gcattaagaa gccagatgga agtcgggcag acgttcacaa atggcgatct
     2161 ttttgacagt gtgcagatga caggtataaa gcttgaaacg gacaccagta tgctgcctga
     2221 cagcgaacaa ggctttgcgc cagtggttcg tggtattgcc aacagcgatg cacaagttgt
     2281 gattaaacaa aacggctatg ttatttacca aacgtgggta tcggcagggc catttgaaat
     2341 taaagactta agccaggtaa cggcgggggc cgatctggaa gtcaccatca aagaaaccaa
     2401 cgggcaagaa cacagtttta ttcaggccag ttcaacggtt ccaattctac agcgagaagg
     2461 cgcattaaaa tatagtcttg caactggaaa ataccgtgac aacgataatc atgctgagac
     2521 acctgttttt ggtgttgcaa ccgcgatata tggcttgccc tatggaataa cgatttatgg
     2581 cggcatactt ggtgcctcaa tttatcattc tggtgtgaca gggattggcg ctgatttagg
     2641 ccgtctgggg tcggtatctg ttgatatcac cgcagcagaa acgaagtttg atgatgggcg
     2701 tgatgatgct acaggactgt catggcgtgc acagtatgcg aaagattttc cagacactga
     2761 tacgacagta actctggcaa gttatcgtta ttctacatca caattttaca ctttccagga
     2821 agcacttgat caacgtgata cacctgatga caagggtatt tacagttatc gacagacaaa
     2881 taatcggcgt aatcgtttac aaattaatct ttcacaaaat attggtcgtt ggggctcggt
     2941 ctaccttaac ggttatcaac aggattattg gggaatgcat ggggccgaac gcagtatagg
     3001 aatgggatac agtacgacct ggagtaacat taattggtct gttaattaca cactaacgaa
     3061 aacgccagga atggctggtg agcagcaatt ttcattaaca ctcaatattc ctctctctcg
     3121 ctggctgcca gattcatggg cgatgtataa cgtaaaccgt tccgataaaa gtaatacatc
     3181 acatcaattg ggaattggcg gtactgctct gcaagataac aacctgagtt ataatttaca
     3241 gcaaagttat actgataata atgtgggtta tgatgccagc atgaatggac gttatcgtag
     3301 ctcagtgggg gaattcggtc tgggatatag ctatgataaa aatagtcgtc agtggaatta
     3361 cagtgcgcaa ggtgcggtgg ttgctcatgc tcatggagta acattggggc aatcagtgca
     3421 ggattcattc gcgatcgtgc atattaatga gggtgccaat gtaaaagtac aaaatgcgca
     3481 aggcgtttat actgattatt ggggaaacgc gattgttccc aatatgacga attatcgaca
     3541 taacgctatt actgtgaata cacaggggca cgatagtctt gatatttctg atgccacaca
     3601 agatgttatt ccttcgaaag gggctgttgt tggtgtcgat tttgatgcac gtagcggaat
     3661 acgagccttg ttgacattag tccataataa agaacgcgta ccctttgggg cattgctgac
     3721 attagggaat agtacagcga ttgttggtga agatggggag gtttatatta ctggtgtgca
     3781 agaatcaatg acatttacgg tacagtgggg aaaagagatt aaccagcaat gtacaggagt
     3841 tgtcacagtg ccagaaaaat acaccacggg tatctataaa gccacaatgg attgccgata
     3901 acaaataaga caggaaaaaa taatgaagcc aggattcgtc tcttatatac gaacattatt
     3961 gaccataata tttcttagct ggggcgtcat tcctgaggtt ttcgccggtt gtaacatttc
     4021 tggaaatgga ggaaatccgg caacagtaca attctccgtg cctgcgttgg ttgttaatag
     4081 cgatgccgtt cctggaacga ttattgcgac agtaaatgcg aacagtccgt caatttcagt
     4141 ttcctgtacg gcaaatggtg agatctggca aggatatacc gtattgacaa acggtgatat
     4201 gcgtactgat aacccactta acaatgtgtt tcagactaat gtgccaggaa tcggttttcg
     4261 cgcggcgtgg gcgaataaca ccagtgcgca actcaccgcc ggatatttaa tgacgccctg
     4321 gcataaaggc tcgtcaacag tgattaaagg atatggttat ccgattacaa tacatgcagc
     4381 tattcagttt attgtcacag gacctgtcgg taatgggacc attgatacca gcaaactggt
     4441 tgctgactgg aagtatgaca atcgtgttat tggagagctt cgttttagtt ctgttccggt
     4501 caatattcaa ccgggcacat gcgaccttat agaaaaaaat attaccgttc cactcaatga
     4561 tattggcaca gatgattttg atgttaacaa tgtgtcacct gtagtttccg atgatcggtt
     4621 taaaattcag attgaaaaat gttctcagga tgtaaaagtt gattaccgct ttacttcatc
     4681 aggttctact ggagtaacgg gtaataatat tcttaatatt gagtctggtt caggaatggc
     4741 ggaaggagtt ggtctgcaga tcctcgatag taataacaat gtgatggtat ttgatacaga
     4801 ctatacacct gttcaaaaaa cgacgttaaa tcaaaatgtt actattccgt taaaagcacg
     4861 ctacatcaaa atgggtagcg tcaaaagtgg tcgggttaat tctgttgcca ccttcgaagt
     4921 gtattaccga taagcttttc cctttgccat aaatgttaat ttttggtaat ggaattttta
     4981 tggtttacgg tgcaaagatt aacatttttg attcatctga ttgattctcg ccccttcatg
     5041 gacgcacaga gcgtatatca cttgcgaacc cgccagcgtt tcgaatatta tcgcatcttt
     5101 ataataatca ttctcgttta cgttatcatt cactttcatc agagatatac caatggcgcg
     5161 ttccaaaact gctcagccaa aacactcact gcgtaaaatc gcagttgtag tagccacagc
     5221 ggttagcggc atgtctgttt atgcacaggc agcggttgaa ccgaaagaag acactatcac
     5281 cgttaccgct gcacctgcgc cgcaagaaag cgcatggggg ccagctgcaa ctattgcggc
     5341 gcgacagtcc gctaccggca ctaaaactga tacgccgatt caaaaagtac ctcaatctat
     5401 ttctgtcgtc accgctgaag agatggcact gcatcagcct aagtcggtga aagaagcgct
     5461 tagctatacc cctggcgttg ctgtgggaac ccgtggcgca tctaatactt atgattacct
     5521 gatcatccgc ggatttgcgg cagacggcca aagccagaac aactatctga atggcctgaa
     5581 gatgcagggc aacttctata acgatgcggt tattgaccca tatatgctgg agcgcgctga
     5641 aatcatgcgt ggcccggttt ccgtgctgta tgggaaaagc agcccaggcg gcctgttgaa
     5701 catggtcagc aagcgcccga ccactgaacc gttgaaagaa gttcagttta aggccgggac
     5761 tgacagccta ttccagactg gttttgactt cagcgatgcg ctggatgatg acggcgttta
     5821 ctcttatcgc ctgaccggcc ttgcgcgttc tgcgaatgcc cagcagaagg gggctgaaga
     5881 gcagcgttat gctattgctc cagcgtttac ctggcgtccg aatgataaaa ccaatttcac
     5941 tttcctttct tacttccaga acgagccgga aaccggttat tacggctggt tgccgaaaga
     6001 ggggactgtc gaaccgctgc caaacggtaa gcgtctgccg accgacttta acgaaggcgc
     6061 gaagaacaac acctattctc gtaacgagaa gatgattggt tatagcttcg accacgaatt
     6121 taacgacacc tttactgtgc gtcagaacct gcgctttgca caaaataaag tctcgcaaaa
     6181 gagcgtatat ggctacggca tgtgctcaga cccgctctat tcttcaaacc cctcttcgag
     6241 tccatgtgct aacgtgccgc agtctcaatg gggccataca ctgactcgtc agtacgttat
     6301 cgataatgag aagttagaaa acttctctgt tgatactcag ttgcaaagca aattcgcaac
     6361 cggttcagtg gatcacactc tgctgactgg cgttgacttt atgcgtatgc gtaatgacat
     6421 cgattcctgg tttggttatg ccggttcagt tgcaccatct gatatctata atttagaccg
     6481 tagtgacttt gattttggcg ctcacccgaa tccgtctggt ccataccgcg ttctgctgaa
     6541 acagaaacaa accggcctgt atgttcagga tcaggcgcag tgggataaag tgctggttac
     6601 gcttggcggt cgctatgact gggccgatca gtcatctttc aaccgtgatt acggtaataa
     6661 atctgaacgt gacgacaaag agttcacctg gcgtggtggt gtaaactacc tgttcgacaa
     6721 cggcgtaacg ccttacttca gctacagtga atcatttgaa cccgcttcac agactgatgc
     6781 gaacggcgat ctgtttgcac cttcgaaagg caaacagtat gaagtcggcg tgaaatatgt
     6841 gccagaagat cgcccaattg tggtgactgg cgcactgtat cagcttacca aaactaataa
     6901 cctgatggcg gatccgaacg gttcactgtt ctcggttgaa ggcggtgaga ttcgtgcgcg
     6961 tggcgtagag ctggaagcga aagcggcact gtcggcgagt gttaacttgg ttggttctta
     7021 cacctatact gacgcggaat acaccactga caccaactac aaaggaaata cgcctgcaca
     7081 ggtgccaaaa cacatggctt cgctgtgggc tgactatacc ttctttgacg gtccgctttc
     7141 aggtctgacg ctgggcaccg gtggtcgtta tactggctcc agctatggtg atccggctaa
     7201 ctcctttaaa gtgggaagtt atacggtcgt ggatgcgtta gtgcgttatg atctggcgcg
     7261 agtcggcatg gcgggctcca acgtggcgct gcatgtcaac aacctgttcg atcgtgaata
     7321 cgtcgccagc tgctttaaca cttatggttg cttctggggc gcagaacgtc aggtcgttgc
     7381 aaccgcaacc ttccgtttct aatttctctt tttggggcac ggatttccgt gcccgtttca
     7441 caagttggct gttatgcagg aatacacgaa tcattccgat accacttttg cactgcgtaa
     7501 tatctccttt cgtgtgcccg ggcgcacgct tttgcatccg ctgtcgttaa cctttcctgc
     7561 cgggaaagtg accggtctga ttggtcacaa cggttctggt aaatccactc tgctcaaaat
     7621 gcttggtcgt caccagccac cgtcggaagg ggagattctt attgatgccc aaccgctgga
     7681 aagctggagc agcaaagcgt ttgcccgcaa agtggcttat ttgccgcagc agcttcctcc
     7741 ggcagaaggg atgaccgtgc gtgaactggt ggcgattggt cgttacccgt ggcatggcgc
     7801 gctggggcgc tttggtgttg cagatcgcga aaaggtcgag gaagctatct cgctggttgg
     7861 cttaaaaccg ctggcgcatc ggctggtcga tagcctttct ggcggcgaac gtcagcgggc
     7921 gtggatcgcc atgctggtgg cgcaggatag ccgctgtctg ttgctcgacg aaccgacttc
     7981 ggcgctggat atcgcccacc aggttgatgt actggcgctg gtgcatcgtt taagtcagga
     8041 gcgtggcctg acggtcattg ccgtgctgca cgatatcaat atggcggcgc gctactgtga
     8101 ttatctggtc gccctacgcg gcggtgaaat gattgctcag ggaacgcctg cggaaattat
     8161 gcgcggcgaa accctcgaaa tgatttatgg catcccgatg ggtattctgc cgcatccggc
     8221 gggtgctgca cctgtgagtt ttgtttattg atgagcggct tacctcttat ttcgcgccgc
     8281 cgactgttaa cggcgatggc gctttctccg ttgttatggc agatgaatac cgcccacgcg
     8341 gcggttattg atcccaatcg tattgtggca ctggagtggt tgccggtgga gttactgctg
     8401 gcgctcggca tcgtgcctta cggcgtggcg gacaccatca actatcgcct gtgggtcagc
     8461 gaaccgccat tgccggactc agtgattgac gttggtttgc gtacagaacc caaccttgaa
     8521 ctgctgaccg aaatgaaacc gtcgtttatg gtctggtctg caggatatgg cccttcacca
     8581 gaaatgctgg cacgtattgc gccggggcgc ggatttaact tcagcgacgg caaacagcca
     8641 ctggcgatgg cgcgtaaatc actgacggaa atggcagatt tacttaacct gcaaagcgca
     8701 gcggaaacgc atttagcgca ctatgaagac tttatccgca gcatgaaacc ccgctttgtg
     8761 aagcgtggtg cacgcccgtt attgctgacg acgcttatcg atccgcgcca tatgttggtc
     8821 ttcggtccaa acagcttgtt ccaggaaatt ctcgatgagt acggcatccc aaatgcctgg
     8881 caaggggaaa ccaacttctg gggcagtacc gccgtcagta tcgatcgtct ggcagcgtat
     8941 aaagacgttg atgtgctctg ttttgatcac gacaacagca aagacatgga tgcgctaatg
     9001 gcaaccccgc tgtggcaggc catgccgttt gtccgcgccg gacgctttca gcgcgtacct
     9061 gcagtttggt tctatggtgc gacgctttct gcaatgcact ttgtgcgtat tctggataac
     9121 gccatcggag gtaaagcgtg agtaaacgaa ttgcgctttt tccggtgtta ttgctggcgc
     9181 tgctggtggt tgctgctgcg gcgttgacct ggatgaactt ctcgcaggcg ctgccgcgca
     9241 gccagtgggc gcaggccgcc tggtcgccgg atattgacgt catcgagcag atgatttttc
     9301 actacagctt gttgccgcgt ctggcgattt cgctgctggt gggcgcgggc ctggggatgg
     9361 tgggcgtgct gtttcagcaa gtgctgcgta acccgctggc ggaaccgacg acgttgggtg
     9421 ttgcaacagg cgcgcaactg gggattaccg tcaccacgct ctgggcgatc cccggcgcga
     9481 tggcgagcca gtttgctgcg ctggcagggg cttgtgttgt tggcttaatc gtctttggcg
     9541 tcgcgtgggg gaaacggctt tcgccggtaa cgctgatcct cgcggggctg gtagtgagcc
     9601 tttattgcgg cgcaatcaat cagttactgg ttatcttcca tcatgaccaa ctgcaaagca
     9661 tgttcctgtg gagcaccgga acgctgacgc aaaccgactg gggcggcgtt gagcgtttat
     9721 ggccgcagct gctgggcggc gtgatgctga cgttattgct acttcgcccg ttaactctga
     9781 tggggcttga tgatggcgtg gcgcgcaatc tcgggctggc cttgtcgctc gctcgtctgg
     9841 cggcgttgtc gctggcgatt gtcatcagtg cgctgctggt gaacgcggtg gggattatcg
     9901 gctttatcgg tttgttcgcg ccactgctgg cgaaaatgct gggggcgcgg cgtttgttgc
     9961 cacggttgat gctggcatcg ctgattggtg cgttaattct gtggctttct gatcaaatca
    10021 tcctctggct gactcgcgtg tggatggaag tgtctaccgg ttcggtcact gcgttgatcg
    10081 gtgcgccgct gctactgtgg ctgctgccgc gtttacgcag cattagcgcg ccggatatga
    10141 aggtcaacga tcgtgtcgcg actgaacgcc aacacgtgct ggcgtttgct ctcgcgggcg
    10201 gcgtgctgct gttgatggct gtggtggtgg cgctgtcgtt tggtcgtgat gcgcacggct
    10261 ggacgtgggc gagcggggcg ttgctcgagg atttgatgcc ctggcgctgg ccgcgaatta
    10321 tggcggcgct gtttgcgggt gtcatgctgg cggtggcggg ctgtattatt cagcggctga
    10381 ccggaaaccc gatggcaagc ccggaagtgc tggggattag ctccggcgcg gcgtttggcg
    10441 tggtgttaat gctgtttctg gtgccgggta atgcctttgg ctggctgtta cccacaggca
    10501 gtctcggggc ggcggtgacg ctgttgatca ttatgatcgc cgccggacgc ggtggatttt
    10561 ccccacaccg catgttactg gcggggatgg cgttaagtac cgcgttcacc atgcttttga
    10621 tgatgttgca ggcaagtggt gacccgcgaa tggcgcaagt tctgacctgg atttccggtt
    10681 cgacctacaa cgcgaccgat gcgcaggtct ggcgtactgg aattgtgatg gtgattttgc
    10741 tggcgattac cccgctgtgc cgccgctggc tgaccatttt accgctgggt ggtgataccg
    10801 cacgagccgt ggggatggcg ctgacgccga cgcgaattgc gctgctgctg ttagcggctt
    10861 gcctgacggc gaccgcgaca atgaccattg gtccgttgag ttttgttggt ttaatggcac
    10921 cgcatattgc gcggatgatg ggctttcgac ggacgatgcc acacatcgta atttcggcgc
    10981 tggtgggagg attactgctg gtgttcgctg actggtgtgg gcggatggta ttgtttccat
    11041 tccagatccc agcggggctg ctgtcgacct ttatcggcgc gccatatttt atctatttgt
    11101 tgagaaagca gagccgttaa taggatgcct cgcccggtgg gcgaggcaaa atcatcacaa
    11161 cttcgcaaac acccgacgtg cagcatcgat ggtgttattg atatcttcca tgctgtgcgc
    11221 cacagacata aagcccgctt caaacgctga cggtgccaga taaacacctt cgtccagcat
    11281 catatggaag aaacgtttaa agcgttccac gtcacaggac atcacatcct ggtagcatgt
    11341 cacggactcg gcgtcggtaa agaaaatacc gaacatgccg ccaacgtggt ttaccaccag
    11401 cggaattccg gcttcttctg ccgcttcccg cagaccttct gccagacgtg ttgtcagctc
    11461 atccagcgtc tcgtgaacgc ccggctgtgc gacttcattc agacaggcga aaccagcagc
    11521 catcgcaatc gggttaccgg aaagcgtacc cgcttgatag accggaccgg tcggggccag
    11581 cgcatccatt acatcacgac gaccaccgaa tgcgcctacc ggcattccac cgccgatgat
    11641 tttgccgagg caggtgagat ccggttccac accgtaataa tcctgtgcgc cagctagcgc
    11701 tacgcggaaa ccggtcatca cttcatcgat gatcagcaac gcgccaaatt cgtcgcacag
    11761 cgcgcgcaga cctggcagga actctggcag cggtggcacg cagttcatat tgcctgccac
    11821 cggctcgacg ataatacagg caatctcttg cgggtattgc tcaaacgcgg cgcgtacaga
    11881 ggccagatcg ttataagtac aggttaaggt atgtttggcg aaatctgccg gaacacccgg
    11941 cgaatttggc tggcctaacg tgagtgcgcc agaaccggct ttcaccagca agcagtcagc
    12001 gtgaccgtgg taacaacctt caaatttaat aattttgtcg cgaccggtaa aaccacgggc
    12061 caggcggatg gcgctcatcg tcgcctcggt gccggagttc accatgcgca ccatatccat
    12121 ggtcgggacc agttcggtca ccagttgcgc cattttcact tccatttcgg ttggtgcacc
    12181 aaagcttaaa ccacgctcgg cggcttcaat cacggcattg cggatcgccg gatggttatg
    12241 gcccagcacc atcggccccc aggaaccgac ataatcgata taggctttgc catcaacatc
    12301 gtacagataa gcgccgtccg ctttttcgat aaacagtgga gtgccgccca cgccagtaaa
    12361 ggcgcgaaca ggggagttca cgccgccagg gatcagctcg cgcgctgcgc tgtaaagatt
    12421 ttcagactta ctcatggagg gttcctgatt cgtagaaaaa gtgaatggct gctattctat
    12481 gttattcata acaagttaaa tactcgtcaa acatcaggct gcttgtactg gtgcaatcct
    12541 gatttcttag agtataaaag ttttgtgcat ttgaaacatt acgctttgca aaggattttc
    12601 atggaacgtg cgagtaaaat gccgtcatct tatttgtatg accaataagt gatcattgga
    12661 tgaaaactga tactccctct ttagaaacac cgcaggccgc gcgcctgcga cgcagacaac
    12721 tgattcgcca acttcttgag cgcgataaaa ccccgttagc cattttgttt atggcggcag
    12781 tcgtcggcac gcttgtcggg ctggctgcgg ttgcttttga caaaggtgtc gcctggttgc
    12841 agaaccaacg tatgggggca ctggtacata ctgctgataa ttatccgctt ctgttaaccg
    12901 tcgcttttct ctgttcggcg gtgctggcga tgttcggcta ctttttggtg cgcaaatacg
    12961 cgccggaagc aggtggttcg gggatcccgg aaattgaagg ggcgctggaa gatcaacgtc
    13021 ctgttcgctg gtggcgtgtg ttgccggtga aattctttgg tgggctgggg acactcggcg
    13081 gaggcatggt gttggggcgc gaagggccaa ccgtgcagat aggcggcaat atcgggcgga
    13141 tggtactcga tgttttccgc ctgaaaggtg acgaagctcg tcatacgcta ctggcaaccg
    13201 gtgctgctgc ggggctggct gcggccttta acgcgccgct ggcgggtatt ttgtttatta
    13261 tcgaagagat gcgtccgcag tttcgctata cgttaatttc gattaaagcg gtatttattg
    13321 gcgtcattat gtcgaccatt atgtaccgga tttttaatca tgaagttgcg ttgattgacg
    13381 tcggtaaact ttctgatgcg ccgcttaata cgctgtggct ttatctgatc ctcggtatta
    13441 tttttggcat tttcggccct atttttaata aatgggtgct ggggatgcag gatttgctgc
    13501 accgtgtgca cggtggcaat attaccaaat gggtactgat gggcggtgcg attggcggtt
    13561 tgtgtggatt gctggggttt gtggcaccag caacttcggg cggcggtttt aacctgattc
    13621 ctatcgctac cgcggggaat ttcagcatgg gaatgctggt gtttatcttc gtcgcgcggg
    13681 tcattaccac cttactctgc ttctcttccg gcgcgccggg cggtattttt gccccgatgc
    13741 tggcgctggg tactgtgctg ggaaccgctt tcggaatggt tgccgttgag ttgtttccgc
    13801 aatatcacct tgaggcgggg acgtttgcta ttgccggaat gggggcgtta ctggcggcat
    13861 ctattcgcgc gccgttaacg gggatcattc tggttctgga aatgaccgat aactaccagc
    13921 tcattttgcc aatgattatt accggtcttg gcgcaacact attagcacaa tttaccggtg
    13981 ggaaaccgct atactcggcg attcttgcgc gcacgctggc aaaacaggaa gctgagcaac
    14041 tggcgcgaag caaggccgca tcagccagcg agaatacttg aacgaaatac cagggtatta
    14101 gataatggcg attattattg ggttagaatt tgcccaattg ccgatgtcgt ttggagcaaa
    14161 atatgagtga tgacgtagca ctgccgctgg agtttaccga cgcagcagcc aacaaagtta
    14221 aaagcctgat cgctgacgaa gataacccga atctgaaatt acgcgtgtat atcaccggtg
    14281 gcggttgcag cggcttccag tatggtttca cctttgatga tcaggtgaac gaaggcgata
    14341 tgaccatcga aaaacagggc gttggcctgg tggttgatcc gatgagcctg caatatctgg
    14401 tcggcggttc cgttgactat accgaaggtc tggaaggttc tcgtttcatc gtgaccaacc
    14461 cgaacgcgaa aagcacctgc ggttgcggtt cttcctttag tatctaatct gctgttcatg
    14521 tgccggataa actatccggc acatctcctc tcttcaacga ccattctcat ccagcgcaaa
    14581 cgtcggtagc ttaagatgcc aacgaatagc cgccagccga atcaatagcg tcacgaccat
    14641 gcccatcata ctggctgttt ccagtggtac ggaaaatgtg taataagccg tagcgtggac
    14701 aataccgccg ataatacagg cagttgcgta gatttctgta cgtaaaatca tggggatttc
    14761 gcgggccagt acatcacgaa tgattccgcc gccaacgcca gtaatgacgc ccatacaaac
    14821 cgcgattaac ggaccggctt ccgcattaaa ggctttattc acgccaatgc cgacaaacac
    14881 cgccagacca acggcgtcca gcaccggcaa catccatttt ggtaagcgtc ttggctggcg
    14941 caccagcacg atggtcagca tgctggtgac cattgcaacg accagatcgg tgggatcttt
    15001 cacccaaaat accgggccgt gatccagcgc catgtcgcga attgttccgc cgcctactgc
    15061 ggtaaccacg cccaatacca gaacaccaaa agggtccata cgcaattttc cggctaacaa
    15121 aacgccagag atagcaaata ccgctgtgcc gactatatcc agccaataga cgagcattgt
    15181 tcaatcccca ctgagcacct gaaaaggtca ggcactaatc tacctgtgaa agcgcattac
    15241 agagctgttg tgcagcgagg ataatacgtg ggcttgcacg ttcaaaccag tcactcgtga
    15301 gaggaataac gggaattttg agctgttcac cccagtattg tttgatttta ggaatttggt
    15361 ccggtccgcc tgtaatgaca atcgcctgtg gcgagcgtgc taacacctgt tcgcggctaa
    15421 cttgcggcca gggaacccgg ctgtctttaa agatgttttc tccgccacaa acttcgagta
    15481 cctggttctg aatcgactct tttccactgg taaatggcgg attaatgccg aattgcagaa
    15541 aaacacgttt tttaggttta tcagcatatt gcgctttcaa ttgcgcgtac tgatccagca
    15601 gggattgcgc ggcttgttcg gccttatccg gttgcggact ccagggggcc agttgacgta
    15661 acgcattggc aatttgttca atgcttgtcg catcgaccca catcactttt attcccagcg
    15721 aagccagctg gtcaacctgc cgctcggcat tacctccacg ccaggcaatc accagatcgg
    15781 gtttcagcgc gacaatgcgt tccagattca tcccctgcca ggtggaaacc tgctcaatct
    15841 tttgcgcttg tggaggatag tcggaatagc tgctgacccc aaccggcgtg atcccggcgg
    15901 caaaggcaag ttcagtgttg gcgggagaaa gcgtgatgac gcgcggcgcg gcattgagcc
    15961 acagcggcgc gagaaaagac agggcgacca gcgccctgaa cagtgactta gccatgtgcc
    16021 agtttctgca ccagtgactc aaccatcagg ctggactgtt tagcggcaac agccaggaac
    16081 tcatcgaagc taagatgaga ctgttgatcg gccacgtcgg agatggcgcg tactacgaca
    16141 aacgggacgt tgaaattgtg gcagacatgg gcgattgccg tcgcttccat ctctacagca
    16201 atggcctgtg ggaagttgtg gcggattttc gccagaccaa cagaaccgtt gatgaaagcg
    16261 tcgccgctaa caatcaggcc acgtacagcg ttaagattca gttcggcaat gcaggcctca
    16321 gcggcagcga tcagtttatc gtcagctttg aagcctgccg ggcagcctgg taactgaccg
    16381 tattcataac caaatgccgt gacatccgcg tcgtgataac gcgcttcgtc cgagacaacg
    16441 atatcgccca ctttcagcgt tggtgccagg ccaccggcag aaccggtgtt aataatcaca
    16501 tctggcttgc agtgttccaa cagcaaagtg gcacccagcg ccgcagcgac tttaccgatg
    16561 cccgatttca gaagcgcaac ctcggttcca ttcagttggc cggtatagat ttcgcaaccg
    16621 cccagactga tagtttgacg gttttcgatt ttgtcacgca gcagcgtaac ttcttcttcc
    16681 attgcaccaa tgatgccgat tttcatagat ttactcgcga taagcccgat ttgaaggcat
    16741 agtttaccat gcgcttacgg ggaagcgtat ttctcacgcg ggagaggaca tggcacagat
    16801 tgatttccga aaaaaaataa actggcatcg tcgttaccgt tcaccgcagg gcgttaaaac
    16861 cgaacatgag attctgcgga tcttcgagag cgatcgcggg cgtatcatca actctccggc
    16921 aattcgtcgt ctgcaacaaa agacccaggt ttttccactg gagcgcaatg ccgccgtgcg
    16981 cacgcgtctt acccactcga tggaagtcca gcaggtgggg cgttatatcg ctaaagagat
    17041 tttaagccgc ctgaaagagc ttaaattact ggagacgtat ggtctcgatg aactgaccgg
    17101 gccctttgaa agcattgttg agatgtcatg cctgatgcac gatatcggca atccgccgtt
    17161 tggtcatttt ggcgaagcgg cgataaatga ctggtttcgc cagcgtttgt acccggaaga
    17221 tgccgaaagc cagcctctga ctgacgatcg ctgcagcgtg gcggcactac gtttacggga
    17281 cggggaagaa ccgcttaacg cgctgcggcg caagattcgt caggacttat gtcattttga
    17341 aggtaacgca cagggtattc gtttggtgca tacattgatg cggatgaatc tcacctgggc
    17401 gcaggttggc ggtattttaa aatatacccg tccggcgtgg tggcgtggtg aaacgcctga
    17461 gacacatcac tatttaatga aaaagccggg ctattatctt tccgaagaag cctatattgc
    17521 ccggttgcgt aaagaactta atttggcgct ttacagtcgt tttccgttaa cgtggattat
    17581 ggaagctgcc gacgacatct cctattgtgt ggcagacctt gaagatgcgg tagagaaaag
    17641 gatatttacc gttgagcagc tttatcatca tttgcacgag gcgtggggcc agcatgagaa
    17701 aggttcgctc ttttcgctgg tggttgaaaa tgcctgggaa aaatcacgct caaatagttt
    17761 aagccgcagt acggaagatc agttttttat gtatttacgg gtaaacaccc taaataaact
    17821 ggtaccctac gcggcacaac gatttattga taatctgcct gcgattttcg ccggaacgtt
    17881 taatcatgca ttattggaag atgccagcga atgcagcgat cttcttaagc tatataaaaa
    17941 tgtcgctgta aaacatgtgt ttagccatcc agatgtcgag cagcttgaat tgcagggcta
    18001 tcgggtcatt agcggattat tagagattta tcgtccttta ttaaacctgc cgttatcaga
    18061 ctttactgaa ctggtagaaa aagaacgggt gaaacgtttc cctattgaaa cgcgcttatt
    18121 ccacaaactc tcgacgcgcc atcggctggc ctatgtcgag gctgtcagta aattaccgtc
    18181 agattctcct gagtttccgc tatgggaata ttattaccgt tgccgcctgc tgcaggatta
    18241 tatcagcggt atgaccgacc tctatgcgtg ggatgaatac cgacgtctga tggccgtaga
    18301 acaataacca ggcttttgta aagacgaaca ataaattttt accttttgca gaaactttag
    18361 ttcggaactt cgcgctataa aacgaatctg aagaacacag caattttgcg ttatctgtta
    18421 atcgagactg aaatacatga aaaaaaccac attagcactg agtgcactgg ctctgagttt
    18481 aggtttggcg ttatctccgc tctctgcaac ggcggctgag acttcttcag caacgacagc
    18541 ccagcagatg ccaagccttg caccgatgct cgaaaaggtg atgccttcag tggtcagcat
    18601 taacgtagaa ggtagcacaa ccgttaatac gccgcgtatg ccgcgtaatt tccagcagtt
    18661 cttcggtgat gattctccgt tctgccagga gggttctccg ttccagagct ctccgttctg
    18721 ccaggggggc ccgggcggta atggcggcgg ccagcaacag aaattcatgg cgctgggttc
    18781 cggcgtcatc attgatgccg ataaaggcta tgtcgtcacc aacaaccacg ttgttgataa
    18841 cgcgacggtg attaaagtcc agcttagcga tggtcgtaag ttcgacgcga agatggttgg
    18901 caaagatccg cgctctgata tcgcgttgat ccagatccag aacccgaaaa acctgaccgc
    18961 aattaagatg gcggattctg atgcgctgcg cgtgggtgat tacaccgtag caattggtaa
    19021 cccgttcggc ctgggcgaga cagtaacttc cgggattgtc tctgcgctgg gacgtagcgg
    19081 cctgaacgct gaaaactacg aaaacttcat ccagaccgat gcagcgatca accggggtaa
    19141 ctcaggtggt gcgttggtta acctgaacgg cgaactgatt ggtatcaaca ccgcgatcct
    19201 cgcaccggac ggcggaaaca tcggtatcgg ttttgctatc ccgagcaaca tggtgaaaaa
    19261 cctgacctcg cagatggtgg aatacggcca ggtgaaacgt ggtgagttgg gtattatggg
    19321 cactgagctg aactccgatc tggcgaaagc gatgaaagtt gacgctcagc gcggtgcttt
    19381 cgtaagccag gttctgccga attcttccgc cgcgaaagcg ggcattaaag cgggtgatgt
    19441 gatcacctca ctgaacggta agccaatcag cagctttgcc gcactgcgtg ctcaggtggg
    19501 cactatgccg gtaggtagca aactgaccct gggcttactg cgcgacggga agcaggttaa
    19561 cgtgaacctg gaacttcagc agagcagcca gaatcaggtt gattccagca ccatcttcaa
    19621 cggcattgaa ggcgctgaga tgagtaacaa aggcaaagat cagggcgtgg tggtgaacaa
    19681 cgtgaaaacg gggactccgg ctgcgcagat cggcctgaag aaaggtgatg tgattattgg
    19741 cgcgaaccag caggcagtga aaaacatcgc tgaactgcgt aaagttctcg acagcaaacc
    19801 gtctgtgctg gcactgaaca ttcagcgcgg cgacagcact atctacctgt taatgcagta
    19861 atctccctca accccttcct gaaaacggga aggggttctc cttacaatct gtgaacttca
    19921 ccacaactcc atacatcttc atcatccttt gggcatttgc acaatgccgt acgttacgta
    19981 cttccttatg ctaagccgtg cataatggag gacttatggc tggttggcat cttgatacca
    20041 aaatggcgca ggatattgtg gcacgtacca tgcgcatcat cgataccaat atcaacgtaa
    20101 tggatgcccg cgggcgaatt atcggcagcg gcgatcgtga gcgtattggt gaattgcacg
    20161 aaggagcatt gctggtactt tcacaaggac gagtcgtcga tatcgatgac gcggtggcac
    20221 gtcatctgca cggtgtgcgg caggggatta atctaccgtt acggctggaa ggtgaaattg
    20281 tcggcgtaat tggcctgaca ggtgaaccag agaatctgcg taaatatggc gaactggtct
    20341 gcatgacggc tgaaatgatg ctggaacagt cgcggttgat gcacctgttg gcgcaggata
    20401 gccgtttgcg ggaagaactg gtgatgaacc tgattcaggc tgaggagaat actcccgcac
    20461 ttactgaatg ggcgcaacgg ctggggatcg atctcaatca accgcgagtg gtggctattg
    20521 ttgaggtcga cagcggtcag cttggtgtgg acagcgcaat ggcggagtta cagcaactgc
    20581 aaaatgcgct gactacgccc gagcgtaata atctagtggc gattgtctcg ctaaccgaaa
    20641 tggtggtgtt gaaaccggcg ttgaactctt ttgggcgctg ggacgcagaa gatcatcgta
    20701 agcgagttga acaactgatt acccgcatga aagagtatgg ccagctgcgt tttcgcgttt
    20761 cgctgggcaa ctattttacc ggtcctggca gtattgcccg atcctatcgt acggcgaaaa
    20821 cgacgatggt ggtgggtaaa cagcggatgc cagaaagtcg ctgctatttt tatcaggatc
    20881 tgatgttacc tgtgttactc gacagtttgc gtggcgactg gcaggccaac gaactggcgc
    20941 gaccgctggc gcggctgaaa gcgatggaca ataacggctt gctgcggcga actctggcgg
    21001 cgtggtttcg ccacaatgtg caaccgctgg caacgtcaaa ggcgttgttt attcatcgta
    21061 atactctgga atatcggctt aatcgtatat cggaactgac cgggcttgat ttgggcaatt
    21121 ttgatgacag gttgctgctg tatgtggcgt tacaactgga tgaagagcgg taggtcgatt
    21181 acaaaattac agccgggtga gactttaccc ggcccacaga atgacattat ttacgcgtca
    21241 gtttttccag atcggcttca atctcgctga tcttattggt tactactgac tccaggtgac
    21301 gtaagtcatc gaggatctta cgcttaagat caacttcgct gcggtcacgc tggcagattt
    21361 gatcaagctc atcaatgata taccgtagat tcgggctgat ttcctggact tctttataac
    21421 cctgccccac accatcagcg acaaccgttt tacgctgacg cggatattta aacttcacgc
    21481 tcttggcgaa aaactcgcct ttgtctttct ggaaatagat tttcagaata tcgttgttgg
    21541 cttcctgccg gaggctgtaa cgatcaattt cttcaggatt ggtaataccc agacttttca
    21601 gattgtcgta catagcgtta cctcaaaatg agtcagtaaa ttgtgcttat tttagcattt
    21661 ggcctggccc gcccggctcg actgtgatcg cagaaagcct ttttcttcca gacttctatc
    21721 atggcgtaaa aatcaaaaaa ttacctgctt tattgtgatg atattccatg ggatggatta
    21781 gcacatttat cttcattttg cgaattacat gacagtccga aacaagatga aaacgtattt
    21841 aaaaaagggg gaaaatgagt aggacgaatt attctgagcc agaaagcaat cgggcagcgt
    21901 cgtgctgccc gtgtacatac ttttagtcga tggtacgcag cagttcgtta ataccaactt
    21961 taccgcgagt tttcgcgtca actttcttaa cgataactgc acagtagaga ctgtatttgc
    22021 catctttcga cggcagatta cctgaaacaa ccacagaccc tgccggaacg cgaccgtagt
    22081 ggatttcgcc ggtttcacgg tcataaatac gggtgctctg accaatgtat acgcccatag
    22141 agatgacgga accttcttcg acaatcaccc cttcaaccac ttcagagcgt gcgccgatga
    22201 agcagttatc ttcaataatg gtcgggttag cctgcagcgg ctccagcacg ccgccgatac
    22261 ccacgccacc ggaaaggtgg acgtttttac caatctgcgc acaggaaccg acggtcgccc
    22321 aggtatcaac catggtgcct tcatcaacat atgcgccgat gttgacgtaa gacggcatca
    22381 gcacggtgtt acgggcaatg aacgcgccct gacgcactgc cgctggtggc acgacgcgga
    22441 agccttcttt ctggaaacgt gcttcatcgt agttagcgaa tttcatcggc actttgtcga
    22501 agtagcggct ttctgcccct tcgatcacct gattatcatt aatacggaaa gagagcagca
    22561 ccgctttttt caaccactga tgcgtcaccc actgaccgtc aattttttcc gctacacgca
    22621 gtgcgccgga atccagcagg gcgatcacct gatttaccgc ttcgcgggta acggtgtctg
    22681 cattggctgg cgtgatctcg gcacggcgtt caaaagcggt ttcaataatg ttctgtaact
    22741 gctgcattgt taaactcttt tcatatcagt aaacacatca ccctttatcg tttggattga
    22801 gggcctctgt caaccgctga tgcacttcct gctgcaactc gttattaagc gcacgccggt
    22861 cagcggtggc aattatgaat aaatcttcta ctcgctcgcc aatggttgta attcgggcgc
    22921 catgaagcga aattcccaga tcggcaaaaa ttttcccgac tcgcgccagc agtccaggtt
    22981 ggtcgagggc gatcagttcg aggaacgatt tgcggtcggt atgggtcggc aaaaacgtca
    23041 cttcggtttc aacagtaaaa tggcgcaatt tagcgggttg gcgacggggc tgcggtggct
    23101 gccagctact ttgtgtcagc acctgctcca gaccaaaccg aataacctca tgacgatctg
    23161 cggatagcgg gctaccatcg ggttccagca ctataaaggt atccatcgcc ataccgtcgc
    23221 gagtggtgaa aatttgtgcg tcgtgaacac ttaaattgcg gcggtctaat tcggcacaga
    23281 cggcggcaaa cagatagggg cggtccgggc tccagataaa aatctcggtg cctccacgcg
    23341 tagcctgcgg gctaagcagt accagcggtt tgcttaaatc atgctgtaat aaatggcgtg
    23401 cgtgccaggc cagttgattt gggctatggc ggacaaaata gttagcgcga cagcgtgacc
    23461 aaatttggtg cagcgcctct tcgtcgatgt tatccatgcg cagtagtgcc agcgcctgga
    23521 gttggtgatg gcgaacccgt tcgcgcatat ccggcgtgtt ttgcattccg cgtcgtagct
    23581 gcttttcggt ggcaaaatag agttcgcgca acagactttg cttccagcta ttccacagtg
    23641 tttcgttggt ggcgcaaatg tcagccactg tcaggcatac cagatagcgc agacgatttt
    23701 ccgtttggac ttcttcggca aactgcttga tgacttccgg gtcctgaata tcgcggcgct
    23761 gagctgtcac cgacatcagc aagtgctggc gaaccagcca ggcgaccagc tgtgtttcgc
    23821 gtgagttcag cccgtggagt tcggcaaaat gcactacatc ctgagcaccg agaatggagt
    23881 ggtcgccgcc gcgtcctttg gcgatatcgt gaaacagcgc ggcgatgaaa atcagctcag
    23941 ttgacggcag acgcggccag acgtccacac acaacggatg gcgctggcgc gtttcttcac
    24001 tggcaaaact ctccagtttc aacatcacgc ggatagtatg ttcatccacc gtgtaggcgt
    24061 ggaacagatc aaactgcatc tgcccgacga tatgcgacca ttgcggcata tacgcgccga
    24121 gtacgctatg gcgatgcatt ggcaatagcc cgcgccgcac cgctccgggg tgacgcagaa
    24181 tgctcaaaaa cagttttcgc gcttccggaa tattacacag aggttgttgc agatggcgac
    24241 gggcgtggcg taactggcgt agcgtggtgg agtaaatgcc ggtgatcgca ctgttgcgca
    24301 ccatggtgta gaacatacgc aagatggctt ccggctggcg cataaatagt gtttcatcac
    24361 gcaggtcgat cagcgttccg cgtagctgaa actcatcgtc gattggacgt ggtttttcgt
    24421 cggcgggaag ggcgaggatg gcttcatcga acagttgcag cagcatctgg ttgagttcac
    24481 tgacgcggcg tgtaacgcgg aagtaatcct tcatcatccg ctcgaccggt tcgttacctt
    24541 caccactgta attcaaacgc tgggcgacgc taagctggcg atcgaataac aggcgattat
    24601 cgtaacgact gacgaccaga tgcagggcaa agcgaatgcg ccacaatata tgcaggcatt
    24661 cgtttaattc cgctcgctcc gcagaggtta agaagccaaa ccctaccatt tcatccagcg
    24721 atgttgcgcc aaaatgacgg cgggccaccc attgcagagt gtggatatcg cgcaagccgc
    24781 cggggctact tttgatgtct ggttcaaggt tgtagctggt gccgtggtaa cgctgatggc
    24841 gctggttctg ttcttcaact ttcgccgcgt agaacttgtc ggaaggccag aatccttcgc
    24901 taaaaatatg tttttgcagt tcgaggaaca gcgcaacatc gccaattaat aagcgggatt
    24961 cgattaaatt ggtggcgacg gttaaatccg ataacccttc cagcatgcac tcttcaagcg
    25021 tgcgcacgct atgacccact tccagcttta catcccagag cagcgttaac agctcgccca
    25081 ctttttgcgc ctgatcgtcc gggagctttt tacggcttaa aatcagtaaa tcgatgtcag
    25141 aaagtggatg cagctcgcca cgaccgtagc caccgacggc gaccaatgcc aggtcggcaa
    25201 tctggctgaa tcccgcttca atccataatc gttgaagaag ctggtcgata aactcggtac
    25261 gcgcctcaat caactgttct gcggagatac cattgtcaaa ggcatcaccc agccaacgct
    25321 ggaaagtatc gatatgggct tttatcccac cgacggttaa ttcatcacgg ggccaggcgc
    25381 atggattttg cggttgaccg tgcagggtgg ggagagcggt gtttgcgtac tgttctggaa
    25441 gggtattcat tgtgcgccac c
//
LOCUS       DAPOXO010000077        24406 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.077, whole genome shotgun sequence.
ACCESSION   DAPOXO010000077 DAPOXO010000000
VERSION     DAPOXO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24406
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.077"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            68..1567
                     /gene="pitB"
                     /locus_tag="ROH59_003713"
     CDS             68..1567
                     /gene="pitB"
                     /locus_tag="ROH59_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HDX4806149.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRFWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGAQVTEFHCHPANTFDAIARVKTMLPGNMESYEPLSV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
     gene            complement(1616..2308)
                     /locus_tag="ROH59_003714"
     CDS             complement(1616..2308)
                     /locus_tag="ROH59_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDX4806150.1"
                     /translation="MQSITPPLIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQ
                     AGNVGRSVTKLPLMGKSLHKTIERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLA
                     CRRRGLIVLTDRYPQDQIPGAYDGTVFPPNIEGGRFVSWLASQERKAFHWMASHKPDL
                     VIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEKVLIDAEK
                     AITDFMTARGYH"
     gene            2482..3195
                     /locus_tag="ROH59_003715"
     CDS             2482..3195
                     /locus_tag="ROH59_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDX4806151.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAATMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNMTALVIYLLSC
                     WRAYKFRKMLCKSQQGYLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELK
                     LYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGARILELDGR
                     QPADEILQASLRAIQAALS"
     gene            3227..4000
                     /locus_tag="ROH59_003716"
     CDS             3227..4000
                     /locus_tag="ROH59_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806152.1"
                     /translation="MDALQTQTVNSTTAPQPNYIPGLIAVVGCDGTGKSTLTTDLVKS
                     LQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTQSMKTKSPA
                     LWAAVIMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATG
                     KISMFLAQRERRLYQKMAQYRPELIIRLGIDIDTAISRKPDHDYAELQDKIGVMSTIG
                     YNGTKILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT"
     gene            4046..5395
                     /locus_tag="ROH59_003717"
     CDS             4046..5395
                     /locus_tag="ROH59_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDX4806153.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQIWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDR
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYVSNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKSFYPEVMRLDPRTTRPWLLGVKSGLLAGGIGILVALAVLI
                     VGKPLISLVFGVKYLEAYDLIQVMLGAIVISMLGFPQESLLLMAGKQRAFLVAQTIAS
                     IGYIVLLFMFCHLFGVLGAAFAYFGGQCLDVVLSLIPTLKAFFQRHSLLYNAAGEKS"
     gene            5395..6219
                     /locus_tag="ROH59_003718"
     CDS             5395..6219
                     /locus_tag="ROH59_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806154.1"
                     /translation="MMRKYFPLEASERLFVAVEEDDVVDAQVSLPPTIALSCTTEIIH
                     DNYALCLQFWLNGVNRQELLRLICKQAKGDELTADERKQFKYMRARYKHLRFAQRLYL
                     KKHQAGFLFGKTTVFLGRFQDGFRNGKKNIVSYYGNLLRVYLSSPVWSLVNYSLRHSQ
                     LESVSGFIAYRQKQMHTLKEIIAKPRLTGREFHDVRKIISQQVSYYDTLRSLDPENKE
                     ALQISRFLAAINGLMGDKHDDMVADDMENRQSYDAPVALDSDIRQRLELLISRFPL"
     gene            6231..6791
                     /locus_tag="ROH59_003719"
     CDS             6231..6791
                     /locus_tag="ROH59_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDX4806155.1"
                     /translation="MSSRLIIALIIMLLAQGVQAHNFVTGKTVTPVYIQEGGELLLNS
                     DDEIHYQKWNSTQLAGKVRIIQYIAGRKSAKKKNSLLIKAVEAANFPQDRFQPTTIVN
                     TDDAIFGTGYFVVGKIEKNKRRYPWAQFVIDGNGLGRVAWRLPEQSSTILVLNKDGQI
                     QWAKDGSLTPEEVDHVIALAQKLINE"
     gene            6822..7892
                     /gene="lptF"
                     /locus_tag="ROH59_003720"
     CDS             6822..7892
                     /gene="lptF"
                     /locus_tag="ROH59_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDX4806156.1"
                     /translation="MKLVEHYIMRGTRRLVLIIVGFLIFIFASYSAQRYLTEAANGTL
                     ALDVVLDIVFYKVLIALEMLLPVGLYVSVGVTLGQMYTDSEITAISAAGGNPGRLYKA
                     VLYLAIPLSIFVTLLSMYGRPWAYAQIYQLEQQSQSELDVRQLRAKKFNTNDNGRMIL
                     SQTVDQDNNRLTDALIYTSTANRTRIFRARSVDVVDPSPEKPTVMLHNGTAYLLDHQG
                     RDDNEQIYRNLQLHLNPLDQSPNVKRKAKSVTELARSAFPADHAELQWRQSRGLTALL
                     MALLAISLSRVKPRQGRFSTLLPLTLLFVAIFYGGDVCRTLVANGAIPLIPGLWLVPG
                     LMLMGLLMLVARDFSLLQKFSR"
     gene            7889..8968
                     /gene="lptG"
                     /locus_tag="ROH59_003721"
     CDS             7889..8968
                     /gene="lptG"
                     /locus_tag="ROH59_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDX4806157.1"
                     /translation="MNVFSRYLIRHLFLGFAAAAGLLLPLFTTFNLINELDDVSPGGY
                     RWTQAVLVVLMTLPRTLVELSPFIALLGGIVGLGQLSKNSELTAIRSTGFSIFRIALV
                     ALVAGILWTVSLGAIDEWVASPLQQQALQIKSTATALGEDDDITGNMLWARRGNEFVT
                     VKSLNEQGQPVGVEIFHYRDDLSLESYIFARSASIEDDKTWILHGVNHKKWLNGKETL
                     ETSDNLAWQSAFTSMDLEELSMPGNTFSVRQLNHYIHYLQETGQPSSEYRLALWEKLG
                     QPILTLAMILLAVPFTFSAPRSPGMGSRLAVGVIVGLLTWISYQIMVNLGLLFALSAP
                     VTALGLPVAFVLVALSLVYWYDRQH"
     gene            complement(9003..10175)
                     /locus_tag="ROH59_003722"
     CDS             complement(9003..10175)
                     /locus_tag="ROH59_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDX4806158.1"
                     /translation="MGLYDKYARLAGERLQFSDNGLTPFGTCIDEVYSATEGRIGNKK
                     VILAGTNNYLGLTFNHDAIAEGQAALAAQGTGTTGSRMANGSYAPHLALEKEIAEFFN
                     RPTAIVFSTGYTANLGVISALADHNAVVLLDADSHASIYDACSLGGAEIIRFRHNDAK
                     DLERRMVRLGERAKEAIIIVEGIYSMLGDVAPLAEIVDIKRRLGGYLIVDEAHSFGVL
                     GATGRGLAEAVGVEDDVDIIVGTFSKSLASIGGFAVGSEAMEVLRYGSRPYIFTASPS
                     PSCIATVRSSLRTIATQPELRQKLMDNANHLYDGLQKLGYELSSHISPVVPVIIGSKE
                     EGLRIWRELISLGVYVNLILPPAAPAGITLLRCSVNAAHSREQIDAIIQAFATLKQ"
     gene            complement(10175..10423)
                     /locus_tag="ROH59_003723"
     CDS             complement(10175..10423)
                     /locus_tag="ROH59_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDX4806159.1"
                     /translation="MVNREIVMDYILSCLQDLVENGVEIKPDSDLVNDLGLESIKVMD
                     LLMMLEDRFDISIPINILLDVKTPAQLMETLLPWLENK"
     gene            complement(10455..11369)
                     /locus_tag="ROH59_003724"
     CDS             complement(10455..11369)
                     /locus_tag="ROH59_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001481799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDX4806160.1"
                     /translation="MNQTVAVTGATGFIGKYIIDNLLARGFHVRALTRTARAHVNDNL
                     TWVRGSLEDTHSLSELVTGASAVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESGF
                     CQRFLFISSLAARHPELSWYANSKHVAEQQLTAMADAITLGVFRPTAVYGPGDKELKP
                     LFDWMLRGLLPRLGTPETQLSFLHVTDFAQAVGQWLSAETVQTQTYELCDGVAGGYDW
                     QRVQQLVADVRCGSVRMVGIPLPLLTCLADISTALSRLAGKEPMLTRSKIRELTHADW
                     SASNNRISEDINWFPGISLEHALRNGLF"
     gene            complement(11366..13096)
                     /locus_tag="ROH59_003725"
     CDS             complement(11366..13096)
                     /locus_tag="ROH59_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acyl-AMP ligase"
                     /protein_id="HDX4806161.1"
                     /translation="MVYMSNKIFTHSLPMRYADFPTLVDALDYAALSSAGMNFYDRRC
                     QLEDQLEYQTLKARAEAGAKRLLSLNLKKGDRVALIAETSSGFVEAFFACQYAGLVAV
                     PLAIPMGVGQRDSWSAKLQGLLASCQPAAIITGDEWLPLVNAATHNNPELHVLSHAWF
                     KALPEADVALQRPVPNDIAYLQYTSGSTRFPRGVIITHREVMANLRAISHDGIKLRPG
                     DRCVSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVA
                     PPFGYELCQRRVNEKDLAELDLSCWRVAGIGAEPISAEQLHQFAECFRQVNFDDKTFM
                     PCYGLAENALAVSFSDEASGVVVNEVDRDILEYQGKAVAPGAETRAVSTFVNCGKALP
                     EHGIEIRNEAGIPVAERVVGHICISGPSLMSGYFGDQISQDEIAATGWLDTGDLGYLL
                     DGYLYVTGRIKDLIIIRGRNIWPQDIEYIAEQEPEIHSGDAIAFVTAQEKIILQIQCR
                     ISDEERRGQLIHALAARIQSEFGVTADIDLLPPHSIPRTSSGKPARAEAKKRYQKAYA
                     ASLHVQESLA"
     gene            13458..14600
                     /locus_tag="ROH59_003726"
     CDS             13458..14600
                     /locus_tag="ROH59_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX4806162.1"
                     /translation="MECDLLMIKIEKVINKNDLKAFIAFPSSLYPDDPNWIPPLFIER
                     NEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGKDTGHFGMIDAIDD
                     PQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYA
                     AHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQIL
                     REIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNIN
                     EAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEAL
                     RDPFARRKIDALEMSWILETNTGMNNMLERIGAEPYKRYRLYEKQI"
     gene            complement(14607..15371)
                     /gene="glcC"
                     /locus_tag="ROH59_003727"
     CDS             complement(14607..15371)
                     /gene="glcC"
                     /locus_tag="ROH59_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001305094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GlcC"
                     /protein_id="HDX4806163.1"
                     /translation="MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFS
                     RSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRA
                     LLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
                     SHNQVLEFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQ
                     RAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMKQG"
     gene            15622..17121
                     /gene="glcD"
                     /locus_tag="ROH59_003728"
     CDS             15622..17121
                     /gene="glcD"
                     /locus_tag="ROH59_003728"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcD"
                     /protein_id="HDX4806164.1"
                     /translation="MSILYEERLDGALPDVDRTSVLMALREHVPGLEILHTDEEIIPY
                     ECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRVPVVTRGAGTGLSGGALPLEKGV
                     LLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNV
                     AENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSPGFDLLALFTGSEGMLG
                     VTTEVTLKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAE
                     DFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFW
                     AGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNM
                     HPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQMCAQFNSDEI
                     TTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF"
     gene            17121..18173
                     /gene="glcE"
                     /locus_tag="ROH59_003729"
     CDS             17121..18173
                     /gene="glcE"
                     /locus_tag="ROH59_003729"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcE"
                     /protein_id="HDX4806165.1"
                     /translation="MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQT
                     LDVRCHRGIVNYDPTELVITARAGTPLVAIEAALESAGQMLPCEPPHYGEEATWGGMI
                     ACGLAGPRRPWSGSVRDFVLGTRIITGTGKHLRFGGEVMKNVAGYDLSRLMAGSYGCL
                     GVLTEISMKVLPRPRATLSLRREISLQEAMNEIAQWQLQPLPISGLCYFDNALWIRLE
                     GGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQ
                     LIDWGGALRWLKSTADDNQIHRIARNAGGHATRFSAGDGGFAPLPAPLFRYHQQLKQQ
                     LDPCGVFNPGRMYAEL"
     gene            18184..19407
                     /gene="glcF"
                     /locus_tag="ROH59_003730"
     CDS             18184..19407
                     /gene="glcF"
                     /locus_tag="ROH59_003730"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcF"
                     /protein_id="HDX4806166.1"
                     /translation="MQTQLTEEMRQNARALEADSILRACVHCGFCTATCPTYQLLGDE
                     LDGPRGRIYLIKQVLEGNDVTLKTQEHLDRCLTCRNCETTCPSGVRYHNLLDIGRDIV
                     EQKVKRPLPERMLREGLRQVVPRPAVFRALTQVGLVLRPFLPEQVRAKLPAETVKAKP
                     RPPLRHKRRVLMLEGCAQPTLSPNTNAATARVLDRLGISVMPANEAGCCGAVDYHLNA
                     QEKGLARARNNIDAWWPAIEAGAEAILQTASGCGAFVKEYGQMLKNDALYADKARQVS
                     ELAVDLVELLREEPLEKLAIRGDKKLAFHCPCTLQHAQKLNGEVEKVLLRLGFTLTDV
                     PDSHLCCGSAGTYALTHPDLARQLRDNKMNALESGKPEMIVTANIGCQTHLASAGRTS
                     VRHWIEIVEQALEKE"
     gene            19412..19816
                     /locus_tag="ROH59_003731"
     CDS             19412..19816
                     /locus_tag="ROH59_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein GlcG"
                     /protein_id="HDX4806167.1"
                     /translation="MKTKVILSQQMASAIIAAGQEEAQKNNWSVSIAVADDGGHLLAL
                     SRMDDCAPIAAYISQEKARTAALGRRETKGYEEMVNNGRTAFVTAPLLTSLEGGVPVV
                     VDGQIIGAVGVSGLTGAQDAQVAKAAAAVLAK"
     gene            19838..22009
                     /gene="glcB"
                     /locus_tag="ROH59_003732"
     CDS             19838..22009
                     /gene="glcB"
                     /locus_tag="ROH59_003732"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase G"
                     /protein_id="HDX4806168.1"
                     /translation="MSQTITQGRLRINANFKRFVDEEVLPGTGLDAAAFWRNFDEIVH
                     DLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPERVTVET
                     TGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDP
                     QRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVG
                     YRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVA
                     AVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRHYTAADGSEISLHGRSL
                     LFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPK
                     MHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFIN
                     TGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGM
                     WAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQANIAQSEFN
                     AEFEPLLDDLLTIPVAENANWSVEEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIH
                     NVALMEDRATLRISSQHIANWLRHSILTKEQVQASLENMAKVVDQQNAGDPAYRPMSG
                     NFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH"
     gene            22364..24046
                     /gene="glcA"
                     /locus_tag="ROH59_003733"
     CDS             22364..24046
                     /gene="glcA"
                     /locus_tag="ROH59_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate permease GlcA"
                     /protein_id="HDX4806169.1"
                     /translation="MVTRTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGA
                     ITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDI
                     IRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLC
                     LIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWK
                     GVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKVWRPKNTET
                     AISMGQSAGAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFA
                     PGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISI
                     FILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMF
                     PFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMIS
                     PQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGIITLLQAYVFTGMLVS"
BASE COUNT         5807 a         6011 c         6547 g         6041 t
ORIGIN      
        1 ttgcccatgc cgttaaagtc actgataatg cgtccgttcg taaattcaaa atggcgtaat
       61 ctaatatatg ctaaatttat ttgttggcct tgatatatac acagggcttt tgttattact
      121 tgctctggca tttgtgttgt tctacgaagc aatcaatggt tttcatgaca cggcgaatgc
      181 ggtggcaacc gttatttata ctcgtgccat gcaaccacaa cttgctgtgg tgatggcggc
      241 attttttaat ttttttggcg tgttattggg cggacttagc gttgcctatg ccattgtcca
      301 tatgttacca accgatttgt tgctgaatat ggggtcaact cacggcctgg cgatggtctt
      361 ttccatgctg ctggcggcga ttatctggaa cctgggaacg tggttctttg gtttaccggc
      421 ctccagttcg cacaccttga ttggtgcgat tatcggcatc ggtttaacca acgcgctgtt
      481 aaccggctca tcggtgatgg atgcgttaaa cctgcgtgaa gtgaccaaaa ttttctcctc
      541 gctgattgtt tcccctatcg tcggcctggt cattgcgggt ggtctgattt tcctgctgcg
      601 ccgtttctgg agcgggacga aaaagcgtga ccgtattcac cgcattccgg aagatcgcaa
      661 aaagaaaaaa ggcaaacgta agccgccatt ctggacgcgt attgcgctga ttgtttccgc
      721 tgcgggcgtg gcgttttcgc acggcgctaa cgacgggcag aaagggatcg gcctggtaat
      781 gctggtactg gtggggattg cccctgctgg cttcgtcgtc aatatgaacg cgtccggcta
      841 tgaaattacc cgtacccgcg atgccgtcac caacttcgaa cactacctgc aacagcatcc
      901 tgaactgccg cagaagttga ttgcgatgga acctccattg cctgcggcat cgactgatgg
      961 cgcgcaagtg acggagtttc actgtcatcc ggcaaatacc tttgatgcga ttgcgcgcgt
     1021 taaaacgatg ctgccaggca atatggaaag ctacgagccg ttaagcgtga gtcagcgcag
     1081 ccagctgcgc cgcattatgc tgtgcatctc tgatacttcc gcgaagctgg cgaaactgcc
     1141 aggcgtcagt aaagaagacc agaacctgct gaaaaaactg cgcagcgata tgttaagcac
     1201 cattgagtac gcaccggtat ggatcatcat ggcagtagca ctggcgctcg gcattggcac
     1261 catgattggc tggcgtcgtg tagcgatgac catcggtgag aagattggta agcgcggcat
     1321 gacgtatgcg caaggcatgg cggcacaaat gacggcggca gtgtctatcg gccttgccag
     1381 ttatattggg atgcccgtct ccacaacaca cgtactctca tctgccgtag caggaacgat
     1441 ggtggtggac ggcggtgggt tacagcgtaa aacggtaacc agcatcctga tggcgtgggt
     1501 gtttacttta ccggcggcga tttttctttc tggtgggttg tactggatag cattgcagtt
     1561 gatttaacct tcctgaaaat gcccggtcct ggcgatcggg catttccatt tttgactagt
     1621 gataaccacg cgcggtcata aaatccgtaa tcgctttttc tgcatcaatc agcacctttt
     1681 ccagtggctg attagcatcg atatcaacca gttgtgcacc gccaaaggtt aactgtggcg
     1741 ttatggcaat cttcctcgcc agcgattccc gtttatggtc gggtttacgc gcgcaggcaa
     1801 cttcaaggtc aacattgagt ttgatgacca gatcaggttt atggctcgcc atccagtgaa
     1861 acgctttacg ttcctggctt gccagccatg agacaaaacg accaccttca atgttaggtg
     1921 ggaacactgt accatcgtaa gcgccaggaa tttggtcctg aggataacgg tcggttagaa
     1981 caattaaccc gcgacgacga caggcaagca tatgacgaaa gcgcagtaag cgacgggcga
     2041 caaacgctgt aattaccagc gccggaactg gtcctggcaa tttttttgct gttttcacct
     2101 gatttcgttc aattgtttta tgtaaggatt ttcccatcaa cggtaatttt gtcactgaac
     2161 gaccgacatt tccggcctgt tttcctaaat gaactctttc ggcagcacca tatttttcga
     2221 caacggtaat gagatgttca cacaccgttg acttgcctga accatcgcta ccaataacgg
     2281 caattaatgg aggtgttatt gactgcatga atatatcctt taatttaaat atccattaaa
     2341 aatatttatt tggttaatat gtttttatga aagcgtaatt caggtcaatg tcacaattaa
     2401 ccattgtcac aataaggttg aacggatatt ctgagcacgg accacgtaat attcaataca
     2461 ttatttgctg ccgggttttt cgtgaatcaa cgtaatatgt caataattaa ttccacgcca
     2521 gtgcgtgtta ttgccattgt aggatgtgat ggttcaggta aatcgaccct cacggcaagc
     2581 ctggtaaatg aactggcagc aacaatgcca acagaacaca tttatctcgg gcaatcgtcc
     2641 gggcgaattg gcgaatggat ttcacagctc cctgttattg gcgcaccttt tgggcgttat
     2701 ctgcgaagta aagcggcaca tgtgcacgaa aagccctcca caccgcctgg caatatgact
     2761 gcgctggtta tctatctgct ttcctgctgg cgggcgtata agtttcgcaa aatgttgtgt
     2821 aaaagccagc aaggctatct gctcatcacc gaccgctacc cgcaggttga agtgccgggt
     2881 tttcgctttg atggcccgca attggcaaaa accacgggcg gtaacggttg gataaaaatg
     2941 ttaaggcagc gcgagctgaa gctgtaccaa tggatggcat cttatttgcc cgtattgttg
     3001 attcgtcttg gcattgatga acaaaccgcg tttgcgcgta aacctgacca ccaactggcg
     3061 gcgttacagg aaaaaatcgc cgttacgccg caactgacat ttaatggcgc caggatcctt
     3121 gaactggatg gtcggcaacc agccgatgaa attctgcaag cgtcactacg cgcaattcaa
     3181 gctgcgcttt cctgatcacc aaaatggata ggggatgatt taacgaatgg acgcactaca
     3241 aacacaaact gttaatagta caaccgcgcc gcagcccaac tacattccgg ggctgattgc
     3301 ggtggtcggg tgtgatggca ccggtaaatc cacactgacc accgacctcg tgaaatcgct
     3361 gcaacaacac tggcaaaccg agcggcgcta tctggggctg ctctcgggcg aagacggcga
     3421 caaaatcaaa cgattgccgt tggttggcgt ctggctcgaa aggcgactgg cggccaaatc
     3481 atcgaaaacc caaagcatga aaacccaaag catgaaaacc aaatctccag cgctatgggc
     3541 ggcggtgatt atgtactgct tctcgctgcg aagaatggcg aatctacgca aggttcagcg
     3601 actggcgcaa agtggcgttc tggtggtcag cgatcgcttc ccgcaggctg aaatttcggg
     3661 cttttattat gacggaccgg ggatcggcgt cgaacgtgcg accgggaaaa tcagcatgtt
     3721 tctggcgcag cgcgaacggc gtttatacca aaaaatggcg caataccgtc ctgaattaat
     3781 cattcgtttg gggattgata ttgatactgc catctcccgc aagcctgacc atgactatgc
     3841 cgagctgcag gacaaaatcg gcgtcatgtc gacgattggc tataacggca caaaaattct
     3901 tgagattgat tccagagcgc cctacagcga agtgctggaa caggcacaga aggcggtttc
     3961 tctggttgcc atcgtttctg accgccgaag tttaacttaa ggctggcggg atacttttta
     4021 ctatcaacga taaggtcagg ctgaattggc gggttttaac atcaaacatt ggtttgcaga
     4081 tggcgcgttt cgcaccatta ttcgcaatag cgcctggtta ggctccagta atgtcgtgag
     4141 cgctttactg ggtctgttgg cgctctcgtg tgccggtaaa gggatgacgc ccgccatgtt
     4201 tggcgtactg gtgattgtac aatcgtacgc caagtcgatc agcgatttta ttaagtttca
     4261 gatatggcag ctggtggttc agtacggaac accagcatta accaacaata atccgcagca
     4321 attccgcaat gtcgtctcat tttccttctc gctggatatc gtcagcggcg cggtggcgat
     4381 tgtcggcggc attgccttac tcccttttct ttcccattca ttaggtctgg atgaccaaag
     4441 cttttggctg gcagcgctgt attgcacgct cattccttca atggcttcct ccacgccgac
     4501 cggcattctg cgtgcggtag atcgcttcga tctaattgct gtacagcaag cgacgaaacc
     4561 ttttctgcgc gcagcgggga gcgtcgtagc ctggtatttt gactttggtt ttgcgggttt
     4621 tgttattgcc tggtacgtgt cgaatctggt tggcggcacc atgtactggt ggtttgccgc
     4681 gcgcgaatta cgccgcagaa atatccataa cgccttcaaa ttgaatctgt ttgagtctgc
     4741 ccgacacatt aaaggcgcgt ggagttttgt ctggtcaacc aacattgccc actccatctg
     4801 gtcggcgcgt aactcgtgca gcacagtgct ggtggggatc gtgttaggac ccgctgccgc
     4861 cgggttattt aaaatcgcca tgacattctt cgacgccgcc ggaacgccag cgggtttact
     4921 gggcaaaagt ttttacccag aggtgatgcg tttagatccg cgcaccacca gaccgtggtt
     4981 gttaggcgtg aagtcaggtt tactggcggg cggaattggt attctggtgg cgctcgcggt
     5041 gttgatcgtc ggcaagccgc ttatttcgct ggtgtttggc gttaagtatc tcgaagcgta
     5101 tgacctgatt caggtgatgc tgggcgcaat tgtgatttcg atgctgggct tcccacagga
     5161 gtcattgcta ttgatggcgg gaaaacagcg cgcttttctc gtggcgcaaa ccatcgcctc
     5221 aatcggctac atcgtattgc tgttcatgtt ctgtcatctg tttggcgtgc tgggagcagc
     5281 gtttgcttat ttcggtgggc aatgtctgga tgtggtgctc tcgttaattc cgaccttaaa
     5341 ggcatttttt cagcgccatt ccttgcttta taacgcagcc ggagagaaat cctgatgatg
     5401 agaaaatatt tcccgcttga ggcgagcgag cgtttatttg ttgcagttga agaagatgat
     5461 gtcgttgatg cacaggtcag tttgccgccg actatcgcac taagttgtac caccgaaatc
     5521 atccatgata attacgcgtt atgcctgcaa ttctggctca atggcgtcaa tcgccaggag
     5581 ttactgcgtt taatatgcaa acaggccaaa ggcgatgagc tgactgctga tgagcgcaaa
     5641 caatttaaat acatgcgagc gcgctacaag cacctgcgtt ttgcgcaacg gctgtattta
     5701 aagaagcatc aggccggatt tttattcggc aaaacgaccg tttttttggg gcgttttcag
     5761 gacggttttc gtaacggtaa gaaaaatatt gtgtcgtatt acggcaactt gttacgggtt
     5821 tatttaagct ctccggtctg gtcgttggtg aactattcat tacgccatag ccagttagaa
     5881 agcgtaagcg gttttattgc ctatcggcaa aagcaaatgc ataccctgaa agagataatt
     5941 gccaaaccgc gactcaccgg cagggaattt catgatgtgc gaaaaatcat cagccagcag
     6001 gtttcttatt acgacacctt aagatcgctt gatcctgaaa ataaagaggc gttacagatt
     6061 tcccgcttcc tcgccgccat taatggcctg atgggggata aacacgacga catggtggcg
     6121 gatgatatgg aaaaccgcca gtcgtatgat gcaccggtgg cgctggatag cgatattcgc
     6181 cagcgcttag agctgctgat ttcgcgtttt ccgctataac cggagcaatg atgtcatctc
     6241 gtttgattat tgcgctgatt atcatgctct tagcccaggg tgtgcaggca cacaattttg
     6301 tcactggcaa aacggttacc cccgtttata tccaggaagg cggcgagctg cttctgaata
     6361 gcgacgacga aattcactac caaaagtgga acagcacaca gctggcggga aaagtccgca
     6421 ttatccagta tatcgccggg cgtaagtcgg cgaagaaaaa gaactcactg ttaattaaag
     6481 cggttgaagc ggcaaacttt ccgcaggatc gttttcagcc caccaccatt gtgaacaccg
     6541 atgatgccat ctttggtact ggctattttg tcgttggcaa aatcgaaaaa aataaacgcc
     6601 gctatccgtg ggcgcaattc gttattgacg gcaatggact gggacgcgtt gcctggcggt
     6661 tgccggagca gagttcaacc attctggtgc tgaataaaga cgggcaaatt cagtgggcaa
     6721 aggacggcag cctgacgccg gaagaggtag atcatgtcat tgcgctggcg cagaaactga
     6781 tcaatgaata aaaaattcaa aggattgagg gtgttagtga gatgaagctg gttgaacact
     6841 acatcatgcg tggtacgcgc cgtctggtgc tgattatcgt cggttttctg atctttattt
     6901 tcgccagcta ctccgcacag cgttatctga ccgaagcggc aaatgggacc ttagctcttg
     6961 atgttgtgct ggatatcgtt ttctacaaag tgctgattgc actggagatg ttgttacctg
     7021 ttggtctgta tgtgtcagtt ggcgtgacgc tagggcagat gtataccgac tcggaaatta
     7081 ccgctatctc tgcggcgggg ggcaatccgg gacgcttgta caaagccgtt ctttatctgg
     7141 cgataccgct aagtattttt gtcacccttc tgtcgatgta tggtcggccg tgggcttatg
     7201 cgcagattta tcaactggag caacagtcgc agtcggagct ggatgttcgc cagttgcggg
     7261 caaagaaatt taacactaac gataacggac gaatgatcct ttcgcagacg gttgatcagg
     7321 ataataatcg cctgactgac gcgctgattt atacttctac tgccaatcga acccgcattt
     7381 tccgcgcccg ttcggttgat gtggttgacc catcacctga gaaaccgacc gttatgttgc
     7441 ataacgggac cgcctatctt ctcgatcatc aggggcgtga cgacaacgaa cagatctacc
     7501 gtaatctgca attacatctg aatccgctgg atcaaagccc taacgtcaaa cgcaaagcaa
     7561 aatcggtcac ggagctggcg cgctcagcct ttcctgccga tcatgccgaa ctgcaatggc
     7621 gacaaagccg tggcctgaca gcattgttga tggcgctgct ggccatttca ttaagtcggg
     7681 taaaaccgcg gcaagggcga ttttcaacgt tattgccact gacattgctg tttgttgcca
     7741 ttttttatgg cggcgacgtc tgccgtacgc tggtggctaa cggtgcgatt cccctcattc
     7801 ctggtttgtg gttagtaccc ggactcatgc taatgggcct gctgatgctg gtcgcacgcg
     7861 acttctcttt gctgcagaaa ttttcccgat gaatgttttc agtcgctatt taatccgtca
     7921 tctctttctc ggttttgccg ccgccgcagg gctattgctg ccgcttttta ccaccttcaa
     7981 cctgattaac gaactggatg atgtcagccc gggcggttat cgctggactc aggcggtgct
     8041 ggtggtgctg atgaccttac cgcgtacact ggtcgaactt tcgccgttta tcgcattatt
     8101 gggagggatt gttggcctgg ggcagttatc gaaaaacagt gagcttaccg ccattcgcag
     8161 cactgggttt tctatcttcc gtattgcact ggtggcgctg gttgccggga tattgtggac
     8221 tgtttcgtta ggcgcgatag atgagtgggt ggcgtcgcca ttgcagcaac aggcgctgca
     8281 aatcaaatcg actgccaccg cgttggggga ggacgatgac attaccggca atatgctttg
     8341 ggccaggcgc ggtaatgaat ttgtgacggt gaaatcgctg aacgagcagg gccagcctgt
     8401 gggcgtggag atatttcatt atcgcgacga tctctcgctc gaatcctaca tttttgcacg
     8461 cagtgcctcc attgaagacg acaaaacgtg gatcctgcat ggtgtgaatc ataaaaaatg
     8521 gttgaatggc aaagaaacgc tggaaacatc agataatctt gcctggcaat cggccttcac
     8581 cagtatggat cttgaagagt tatcgatgcc ggggaatact ttttctgtcc gtcagcttaa
     8641 tcattacatc cattatttgc aggaaaccgg acaacccagc agcgaatacc gccttgcact
     8701 gtgggaaaaa ctggggcaac cgatcctgac cctggcgatg attttgctgg ctgtgccgtt
     8761 cacctttagc gccccgcgct cgccagggat gggtagccgt ctcgctgtag gcgtcatcgt
     8821 tggcttactc acctggatca gctatcaaat catggtcaat ctgggattgt tatttgcgtt
     8881 gagcgcacct gttaccgcgc tcggtttacc ggtagcgttt gtgttggtgg cgttgagcct
     8941 ggtgtattgg tatgacagac aacattaaac ccgccgtggc gcaacaccac agcgggctca
     9001 cattactgct tcagagtagc aaatgcctga atgatggcat cgatttgctc acgactgtgg
     9061 gcagcgttta cgctacagcg cagcagagtg atgcctgcag gcgcggcagg tggcaggata
     9121 agattcacat aaacgcccag cgaaataagc tcgcgccaga tgcgtaaacc ttcctctttc
     9181 gaaccgatta ttactggcac taccgggcta atatgtgaac ttaactcata acccagtttt
     9241 tgcagaccgt catacagatg gttggcgtta tccatcagtt tttgccgcag ctctggttgt
     9301 gtggcaatgg ttcttaacga cgagcgcacg gtcgcaatgc aggacggaga aggagaggcg
     9361 gtaaaaatat acgggcggct gccgtagcgc agcacttcca tcgcttccga accgacagca
     9421 aaaccgccaa tcgaggccag acttttactg aaagtaccaa cgataatatc cacatcatct
     9481 tcaacgccaa cggcttcagc cagtccgcgc cccgttgcgc ctaacacgcc aaacgaatgc
     9541 gcttcatcga caatcaaata accaccgaga cgacgtttga tatcaacaat ttccgctaac
     9601 ggcgcaacgt caccgagcat gctgtagatg ccctcaacga tgataatcgc ctctttcgcc
     9661 cgttcaccga ggcgaaccat gcgccgttcc agatctttag catcgttatg gcggaaacga
     9721 ataatttctg cgccaccgag agaacaggcg tcataaatac tggcgtggct gtcggcatcc
     9781 agtaacacca cggcgttatg gtcggcaagt gcgctgatga cgcctaaatt agcggtataa
     9841 ccggttgaaa aaacgatagc ggtagggcga ttgaaaaact cggcaatctc tttctctaac
     9901 gccaggtgcg gcgcataact gccgtttgcc atacgagaac cggtggtgcc ggtgccttgg
     9961 gccgctaacg ctgcctgacc ttcggcgatg gcatcatgat taaaggttaa accgagataa
    10021 ttattggtcc cggccagaat cactttttta ttgccgatcc gaccttcggt ggcggaatac
    10081 acttcatcaa tacaggtgcc aaacggtgtt aacccgttgt cactaaattg cagtcgctcg
    10141 ccagcaaggc gcgcatattt atcgtatagc cccattattt attctccagc catggaagta
    10201 gagtttccat taattgcgca ggggttttga catccagcag aatattaata ggaatggaaa
    10261 tatcgaatct gtcttccagc atcattaaga gatccatcac tttgatcgac tccaggccaa
    10321 gatcgttgac gagatcgctg tcgggcttaa tttccacacc gttttcgacc aaatcctgta
    10381 aacaggaaag gatgtaatcc attactattt cacgatttac catagaaacg ttaacacacc
    10441 tttaaacaag acaatcaaaa tagcccgttg cgtaatgcgt gttccaggct aatcccggga
    10501 aaccaattaa tatcttcaga aatacggtta ttacttgccg accagtcggc atgggttaat
    10561 tcacggattt tcgaacgagt cagcatcggt tctttacccg ccagacggct caacgcggta
    10621 ctgatatccg caaggcaggt gagtagcggc agaggaatac cgaccatccg cacggaacca
    10681 cagcggacat cggcaacaag ctgttggaca cgttgccagt catagcctcc ggcgacgcca
    10741 tcgcataatt cataggtttg cgtctgtaca gtttcggcgc ttaaccactg acccactgct
    10801 tgcgcaaaat cggtgacgtg caggaaagag agctgtgtct ctggcgtgcc aagtcgtggc
    10861 agcagaccgc gcagcatcca gtcaaacagc ggttttaact ctttatcgcc gggaccatac
    10921 acggctgtcg ggcgaaaaac gcccaacgta attgcgtcag ccattgcagt cagctgttgt
    10981 tcggcgacgt gtttggaatt tgcgtaccag gagagttcgg gatggcgcgc cgccagcgaa
    11041 gagataaaca gaaatcgttg gcaaaagccg ctctcttttg ccgcttgcat caggcgcagg
    11101 ctgccgtcaa cgttgcagcg ggtaaaaatc tcttctttgt gcccgcgcac ttgcccggcg
    11161 caatggacca ccgcgctggc tccggtaacc agttcgctaa gcgaatgtgt atcttccagc
    11221 gaaccgcgca cccaagtgag attatcattg acgtgagcgc gggcagtacg cgtcaatgcg
    11281 cgaacgtgaa agccgcgggc gagcaggtta tcaataatat atttaccgat aaacccggta
    11341 gcgcccgtca ccgcgacagt ttgattcatg ccagggactc ctgcacatga agactggcag
    11401 cataagcctt ctgataacgt tttttcgctt ccgcacgggc aggcttgccg gaggatgttc
    11461 ggggaatact gtggggcggc aacagatcga tatccgcggt aacgccaaat tcgctttgga
    11521 tccgtgctgc cagcgcgtgg ataagctgcc cgcgacgttc ttcatcgctg atccgacact
    11581 ggatctgcaa aatgattttt tcctgggcgg taacaaaagc aatcgcatcg ccagaatgaa
    11641 tttccggttc ctgttccgca atatattcaa tatcctgcgg ccagatatta cggccacgaa
    11701 taataatcag atctttaatg cgtccggtga catacagata accgtccagc agataaccga
    11761 ggtcgccggt gtctaaccag cccgtcgcgg caatctcgtc ttgtgaaatc tggtcgccaa
    11821 agtaaccgct catcaggcta gggccggaga tgcaaatatg gcctaccaca cgttccgcga
    11881 caggtatacc tgcttcattg cggatttcaa tgccatgttc cggcaacgct ttaccgcagt
    11941 tgacgaaagt cgatacggcg cgtgtttcag cacccggcgc gacggcttta ccctggtatt
    12001 cgaggatgtc gcgatccact tcgttaacca caaccccgga agcttcatca gagaagctga
    12061 cagccagcgc attttctgcc agtccgtagc acggcatgaa agttttatcg tcaaagttga
    12121 cctgacggaa acattcagcg aattgatgga gttgttctgc ggagatgggt tctgcaccaa
    12181 taccagcgac gcgccagcag gaaagatcca gttcagcgag atctttttca ttcacgcggc
    12241 gctggcacaa ttcatagcca aacggcggcg caacggaaac ggtgccgcga tttttactga
    12301 tcaatttaag ccattgcaga ggacgcatgg caaaatcctg agtgcgcaaa taatctactg
    12361 aaagctgcgt ggcgacgggg gtcaggagaa agccgaccag tcccatatca tggtagaaag
    12421 gcagccagga gacgcagcgg tcgccagggc gtaatttaat cccatcgtgg cttatagcac
    12481 gtagattagc catcacttcg cggtgagtaa tgataacgcc acggggaaaa cgggtgctgc
    12541 cggaggtgta ctggaggtag gcgatatcgt ttggaactgg acgttgaagc gcaacatcgg
    12601 cttccggtaa tgccttaaac caggcgtggc ttaaaacatg taattcggga ttgttatgcg
    12661 tcgcggcatt gaccagtggc aaccactcat caccagtgat aatggctgcg ggctggcaac
    12721 ttgccagtaa cccctgcagt ttggcgctcc aggaatcccg ctgaccgacg cccattggaa
    12781 tcgccaacgg gacggcgact aagccggcat actggcaggc aaaaaaagcc tctacaaacc
    12841 cgctactcgt ttcggcaatc agtgccacgc gatcgccttt tttcaggttc agcgataaca
    12901 accgcttcgc accagcttcg gcacgcgctt ttaacgtctg atattccagt tgatcttcaa
    12961 gttggcaacg tctgtcataa aaattcattc cagcgctact cagagcggca tagtccaaag
    13021 catcaaccag cgttggaaaa tcggcatagc gcataggtag ggaatgcgta aagattttat
    13081 tagacatata caccacgaaa aaattggata tcaaaaataa aatgacaata atgcggtgga
    13141 ttatataggc ataaaagata aatgagatag tattttcatc ggtgcgatat tgaacattga
    13201 tttaaataat aggttttgtt ttgttgtttt tattgtgaat gatatttgat ttatgaatgt
    13261 attaagaatg aaccttgtct gaccgcatta aatcgctaaa aggcattgtg gcgcttcttc
    13321 gttggctgtg atcttatcgt aatcattaat aaataatatt tattcttatt ttgtattcat
    13381 ggtgttgatt attaagatgc cgttcgttgc tgttgcaacc tgtttttcat cgttaattat
    13441 ttgttatcca cagagatatg gaatgcgatc tgctgatgat taaaattgaa aaagtaatta
    13501 ataaaaatga ccttaaggca tttatcgctt ttccgtcatc actttatccc gacgatccaa
    13561 actggatacc ccctttattc attgaacgca acgagcattt gtctgcgaaa aatccgggga
    13621 cggaccatat catctggcag gcgtgggtgg caaaaaaagc ggggcagata gttgggcgta
    13681 ttaccgcgca aatagatacc ttgcaccgcg agcgttacgg caaagatacc ggtcatttcg
    13741 gcatgattga cgccattgat gatccgcagg tttttgccgc gttgtttggc gcagcggaag
    13801 cgtggttgaa gtcacaaggt gcaagtaaga tcagcggtcc tttcagcctg aatatcaatc
    13861 aggaaagcgg attactgatt gaaggtttcg atacaccacc ctgtgcgatg atgccgcacg
    13921 gtaaaccgtg gtatgccgcg catattgaac aattgggtta tcacaaaggc attgatttac
    13981 tggcgtggtg gatgcagcga accgatctca ctttctctcc ggcgctaaaa aaactgatgg
    14041 atcaggtgcg taagaaggtg accattcgct gcatcaatcg ccagcggttt gccgaagaga
    14101 tgcagatcct gcgtgagatt ttcaattctg gctggcagca caactgggga tttgtgccgt
    14161 ttaccgaaca tgaattcgcg accatgggcg accaacttaa atatctggtg ccggacgata
    14221 tgatctacat cgctgagatt gattctgcac cctgcgcgtt tattgtcggc ttgccaaaca
    14281 tcaacgaggc gattgccgat ctgaacggat cgctctttcc cttcggctgg gcaaaattgc
    14341 tgtggcgttt aaaagtcagc ggtgtgcgaa ctgcgcgagt accgctgatg ggcgtgcggg
    14401 acgagtatca gttcagccgc atcggcccgg tgattgcgtt gttattgatt gaagccttac
    14461 gcgatccgtt tgcccgccgg aagatcgatg cgctggagat gtcatggatc ctcgaaacca
    14521 atacaggcat gaataacatg ctggaacgca ttggggcgga gccgtacaag cgttaccgat
    14581 tgtatgaaaa gcagatttga tggcagtcac ccctgcttca tctccagcgg caccgccgag
    14641 cgaatcaaat ggtggccttc cagctcgata tcgtggagat tctttttcac ggtccgcaca
    14701 tgatcgcgtg ctgcgcgctg ggcgacgtgc ggcagccgct gcaacaccgc gttgtagatc
    14761 cgcgcatgct ggcgatcgat ctgctttttt tgctgtggtc gatggtagag attatttacg
    14821 ctggcaaaca ccgaattaaa catcaggtcg gtcaatgatt gcagcgtaaa ctccagcacc
    14881 tgattgtgag aagcctgaca aatggcgaga tggaaagcgt gatccaactg cgcatgttcg
    14941 atcagcgaaa tctctttgtt gttctcactg gcggcgagca ttttttcata acagcgggtt
    15001 atcacaacaa aatcagcctg ggttcccagc gttgccgcca gccttgccga ttcgccctcc
    15061 agtaatgcgc gaacgtcgag cagatcgtac agcgttcgcg gctgcgtact gaacagatgg
    15121 atcagcgggc tggtgtcctg cacccgatta agccgtgcga cacgagaatc gcgaccctgc
    15181 gccgtttcaa taatcccgcg cccgcgcagc acggtcagcc cttcacgcag tgcggagcgt
    15241 gagaagccga gcttttcaca cagtcgacgt tccgagggaa gcggctgacc gaccttcagt
    15301 acgccgtcga taattaaccg ttcgatactc tctgcaacca cttcgcaaat agggcgacgt
    15361 tcatctttca ttcccggacc tcgtgcacag gtaggaccaa tttttctgtt cttaactcgc
    15421 aaaacacgca catcacgtaa gtgattatgt tacatcaatt taacattaag ttaaccaaga
    15481 caaggtcaca gagctggaaa aaaaatggtc tgaccggtag ctaaagagat agacgaaaac
    15541 gaaaagcccg cttaataact gttcacagaa gcagcgcgaa aaaatcagct gccacacaac
    15601 acaacaaagc gaagcctact catgagcatc ttgtacgaag agcgtcttga tggcgcttta
    15661 cccgatgtcg accgcacatc ggtactgatg gcactgcgtg agcatgtccc tggacttgag
    15721 atcctgcata ccgatgagga gatcattcct tacgagtgtg acgggttgag cgcgtatcgc
    15781 acgcgtccat tactggttgt tctgcctaag cagatggaac aggtgacggc gattctggct
    15841 gtctgccacc gcctgcgtgt accggtggtg acccgtggtg caggcaccgg gctttctggt
    15901 ggcgcgctgc cgctggaaaa aggtgtgttg ttggtgatgg cgcgctttaa agagatcctc
    15961 gacattaacc ccgttggtcg ccgtgcgcgc gtgcagccgg gcgtgcgtaa cctggcgatc
    16021 tcccaggccg ttgcgccgca taatctctat tacgcgccgg atccgtcctc acaaatcgcc
    16081 tgttcgattg gcggcaatgt ggcggaaaat gccggtggcg ttcactgcct gaaatatggt
    16141 ctaaccgtac ataacctgct gaaaattgaa gtgcaaacgc tggatggcga ggcgctgacg
    16201 ctgggatcgg acgcgctgga ttcgcctggt tttgacctgc tggcgctgtt taccggatcg
    16261 gaaggtatgc tcggcgtgac caccgaagtg acgttaaaac tgctgccgaa gccgcccgtg
    16321 gcgcgggtgc tgttagccag ctttgactcg gtagaaaaag ccggacttgc ggttggtgac
    16381 atcatcgcca atggcattat ccccggcggg ctggagatga tggataacct gtcgatccgc
    16441 gctgcggaag attttataca tgccggttat cccgtcgatg ccgaagcgat tttattgtgc
    16501 gagctggacg gcgtggagtc tgacgtacag gaagactgcg agcgggttaa cgacatcttg
    16561 ttgaaagcgg gcgcgactga cgtccgtctg gcacaggacg aagcagagcg cgtacgtttc
    16621 tgggccggcc gcaagaacgc attcccggca gtggggcgca tttccccgga ttactactgt
    16681 atggatggca ccatcccacg ccgcgcgctg cctggcgtac tggaaggcat tgcccgttta
    16741 tcgcagcaat atgatttacg cgttgccaac gtctttcatg ccggagacgg caacatgcac
    16801 ccgttaatcc ttttcgatgc caacgaaccc ggtgaatttg cccgcgcgga agagctgggc
    16861 gggaagatcc tcgaactctg cgttgaagtt ggcggcagca tcagtgggga acatggcatt
    16921 gggcgcgaaa aaatcaatca aatgtgcgcc cagttcaaca gcgatgaaat cacgaccttc
    16981 catgcggtca aggcggcgtt tgaccccgat ggtttgctga accctgggaa aaacattccc
    17041 acgctacacc gctgtgctga atttggtgcc atgcatgtgc atcacggtca tttacctttc
    17101 cctgaactgg agcgtttctg atgctacgcg agtgtgatta cagccaggcg ctgctggagc
    17161 aggtgaatca ggcgattagc gataaaacgc cgctggtgat tcagggcagc aatagcaaag
    17221 cctttttagg tcgtcctgtc accgggcaaa cgctggatgt gcgttgtcat cgcggcattg
    17281 ttaattacga cccgaccgag ctggtgataa ccgctcgtgc cggaacgccg ctggtggcga
    17341 ttgaagcggc gctggagagc gccgggcaaa tgctcccctg cgagccgcca cattatggtg
    17401 aagaagctac ctggggcggg atgatcgcct gcgggctggc ggggccgcgt cgcccgtgga
    17461 gtggttcggt ccgcgatttt gtcctcggca cgcgcatcat taccggcact ggaaaacatc
    17521 tgcgttttgg tggtgaagtg atgaaaaacg ttgccggata cgatctctca cggttaatgg
    17581 ccggaagcta cggttgtctg ggtgtgctca ctgaaatctc gatgaaagtg ttaccgcgac
    17641 cacgcgccac cctgagtctg cgtcgggaaa tcagcctgca agaagccatg aatgaaatcg
    17701 cccagtggca actccagcca ttacccatta gtggcttatg ttacttcgac aatgcgttgt
    17761 ggatccgcct tgagggcggc gaaggatcgg taaaagcagc gcgtgaactg ctggggggcg
    17821 aagaggttgc gggtcagttc tggcagcaat tgcgtgaaca acaactgccg ttcttctcgt
    17881 taccaggtac cttatggcgc atttccttac ccagcgatgc gccgatgatg gatttacccg
    17941 gcgagcaact gatcgactgg ggcggggcgt tacgctggct gaaatcgaca gccgatgaca
    18001 atcaaatcca tcgcattgcc cgcaacgctg gcggtcatgc gacccgcttt agtgccggag
    18061 atggtggttt tgccccgcta ccggctcctt tattccgcta tcaccagcag cttaaacagc
    18121 agctcgaccc ttgcggcgtg tttaatcccg gtcgcatgta cgcggagctt taaggagcag
    18181 gctatgcaaa cccaattaac cgaagagatg cggcagaacg cgcgggcgct ggaagccgac
    18241 agcatcctgc gcgcctgtgt tcactgcgga ttttgtaccg caacctgccc aacctatcag
    18301 ctcctgggcg atgaactgga cgggccgcgc gggcgcatct atctgattaa acaggtgctg
    18361 gaaggcaacg acgtcacgct taaaacacag gagcatctcg atcgctgtct cacttgccgc
    18421 aattgtgaaa ccacctgtcc ttctggtgtg cgctatcaca atttgctgga tatcgggcgt
    18481 gatattgtcg agcagaaagt gaaacgccca ctgccggagc gaatgctgcg cgaaggattg
    18541 cgccaggtag tgccgcgtcc ggcggtcttc cgtgcgctga cgcaggtagg gctggtgctg
    18601 cgaccgtttt taccggaaca ggtcagagca aaactgcctg ctgaaacggt gaaagctaaa
    18661 ccgcgtccac cgctgcgcca taagcgtcgg gttttaatgc tggaaggctg cgcccagcct
    18721 acgctttcgc ccaacaccaa cgcggcaact gcgcgagtgc tggatcgtct ggggatcagc
    18781 gtcatgccag ctaacgaagc aggctgttgt ggcgcggtgg actatcatct taatgcgcaa
    18841 gagaaagggt tagcgcgggc gcgcaataat attgatgcct ggtggcccgc gattgaagca
    18901 ggtgccgagg ctattttgca gactgccagc ggctgcggcg cgtttgtcaa agagtatggg
    18961 cagatgctga aaaacgatgc gttgtatgcc gataaagcgc gtcaggtcag tgagctggcg
    19021 gtcgatttag tcgaacttct gcgcgaggaa ccgctggaaa aactggcaat tcgcggcgat
    19081 aaaaaactgg ccttccactg cccgtgtacc ctacaacatg cgcaaaagct gaacggcgaa
    19141 gtggaaaaag tgttgcttcg tcttggattt accttaacgg acgttcccga cagccatctg
    19201 tgctgcggtt cagcgggaac atatgcgtta acgcatcccg atctggcgcg ccagctgcgg
    19261 gataacaaaa tgaatgcgct ggaaagcggc aaaccggaaa tgatcgtcac cgccaacatt
    19321 ggttgccaga cgcatctggc gagcgccggt cgtacctctg tgcgtcactg gattgaaatt
    19381 gtagaacaag cccttgaaaa ggaataacaa aatgaaaact aaagtcattc ttagccagca
    19441 aatggcgagt gcaattattg ccgcaggtca ggaagaggcg cagaaaaaca actggtctgt
    19501 ttccattgct gttgccgatg acggcggtca tctgctggcg ttaagtcgca tggacgattg
    19561 cgcgccgatt gcggcttaca tctcccagga gaaagcgcgt accgccgcgc tggggcgtcg
    19621 tgaaactaag gggtatgaag agatggtgaa caacggacgt accgcgttcg tgactgcgcc
    19681 gttattaacg tcgctagaag gtggcgtacc ggttgttgtg gatgggcaaa ttattggtgc
    19741 cgtgggcgtt tctggtttaa ccggagcaca ggatgcgcag gtcgcgaaag cggcagcagc
    19801 ggtgttggcg aaataagcga aaacgaggag agaaacaatg agtcaaacca taacccaggg
    19861 ccgtttacgc attaacgcca attttaaacg ttttgtggat gaagaagttt taccgggaac
    19921 agggttggac gctgcggcgt tctggcgcaa ttttgatgag atcgttcacg atctggcacc
    19981 agaaaatcgt cagttgctgg cagaacgcga tcgcattcag gcggcgcttg atgagtggca
    20041 tcgcagcaat ccggggccgg taaaagataa agcggcctat aaatctttcc tgcgtgaact
    20101 gggctacctg gtgccgcaac cggagcgcgt aacggtggaa accacgggca ttgacagcga
    20161 aatcaccagt caggcggggc cacagctggt ggttccggca atgaacgccc gctacgcgct
    20221 gaacgcggcg aacgctcgct ggggctcact gtacgatgcg ttatacggca gcgacatcat
    20281 cccgcaggaa ggggcgatgg tcagcggcta cgatccgcag cgtggtgagc aggttatcgc
    20341 ctgggttcgg cgtttcctcg atgaatcact accgctggaa aacggcagct atcaggatgt
    20401 ggtggcgttt aaggtggtcg ataaacaatt acgcatccag ttgaaaaatg gtaaagaaac
    20461 cacgttacgt accccggcgc agtttgtcgg ttaccgtggc gatgccgctg cgccgacctg
    20521 cattttgctg aaaaataacg gtctgcatat tgaactgcaa attgatgcca acgggcggat
    20581 tggcaaagac gatccggcgc atatcaacga tgttatcgtc gaagcggcca tcagtaccat
    20641 tctcgactgc gaagattcgg tcgcggcggt tgatgcggaa gataaaatcc tgctgtaccg
    20701 caacctgctg ggcctgatgc aggggactct gcaagagaaa atggaaaaaa acggtcggca
    20761 aatcgtgcgt aaactgaatg acgatcgtca ttacaccgcc gccgatggct ctgaaatttc
    20821 tctgcacgga cgctcgctgc tgtttatccg caacgtgggt catttgatga ccattcctgt
    20881 gatttgggac agcgaaggca atgaaatccc ggaaggcatt cttgatggcg tcatgactgg
    20941 cgcgattgcc ctctatgatt taaaagtgca gaaaaactcg cgcactggca gcgtctatat
    21001 tgtgaaaccg aaaatgcacg gtccgcagga agtggcgttc gccaacaaac tgtttacccg
    21061 cattgagaca atgctcggta tggcaccgaa taccctgaaa atgggcatta tggatgaaga
    21121 acgtcggacc tcgctgaact tgcgtagctg tatcgctcag gcgcgtaacc gcgtggcgtt
    21181 catcaatacc ggtttcctcg accgtaccgg cgatgaaatg cattcggtga tggaagctgg
    21241 cccgatgctg cgtaaaaacc agatgaaatc gacgccgtgg atcaaagcct acgaacgtaa
    21301 taacgtgctt tccggtctgt tctgtgggct gcgcggtaaa gcgcaaatcg gtaaagggat
    21361 gtgggcaatg ccggacctga tggcagacat gtacagccag aagggcgacc aactgcgtgc
    21421 cggggcaaac acagcctggg ttccgtcacc aaccgctgct acgctccatg cgctgcacta
    21481 ccaccaaacc aacgtacaga gcgtgcaggc caacattgcc cagagcgagt tcaatgctga
    21541 atttgaaccg ctgctggacg atctgctgac tattccggtg gctgaaaacg ctaactggtc
    21601 ggttgaagag atccaacaag agctggataa caacgtgcag gggattctgg ggtacgtggt
    21661 gcgttgggtg gagcagggga ttggttgttc aaaagtgccg gatattcaca acgtggcgct
    21721 gatggaagac cgcgcaacgc tgcgtatctc cagccagcat atcgccaact ggttacgtca
    21781 cagtattctg accaaagaac aggtgcaggc gtcgctggag aatatggcga aagtggttga
    21841 tcagcaaaac gctggcgatc cggcttatcg tccgatgtcg gggaatttcg ctaactcgtg
    21901 tgcttttaaa gctgccagcg atttaatctt cctcggcgtg aaacagccaa acggctatac
    21961 cgaaccgtta ttacacgcct ggcgtttacg cgaaaaagaa agtcattaat agcgtcaaaa
    22021 aagccccggc aagttttatt gtcggggcta tgatagtaac tgcggtagta catttatccc
    22081 ggaaataacc ggagcgatta tcagggttta acaatattaa atacccgtag cgcattacta
    22141 gcgggcctaa aacaacaata tggacatctt aacgatattc tgcgcctgcg tgtgcggaac
    22201 agaaaccctt acccgatata cttgttatgc cagaggtagc aattgcgtta gcagcgtact
    22261 gttgctgtaa agtataacgc ctatatttta cagttcagtc ctcttttgct tattacaacc
    22321 ttaagtatat caagcatata aagataataa gagactgaaa aatatggtta ccaggaccca
    22381 aatgtatatg ccgatgggag gactggggct atccgctctg gtcgccctga tcccgataat
    22441 attcttcttc gttgcactcg cggtattacg tctgaaagga catgtcgccg gagcaataac
    22501 ccttatatta tctattctga ttgcgatatt cgcctttaaa atgccgattg atatggcatt
    22561 tgctgctgcg ggctatggct ttatttatgg attatggcct attgcgtgga ttattgttgc
    22621 ggcggtgttc ctctataaat taaccgttgc cagcggtcag ttcgatatta tccgcagctc
    22681 ggttatctcc atcactgacg atcagcgttt gcaggtgtta ctgattggtt tctcctttgg
    22741 cgcgctgctg gaaggggcgg ctggctttgg tgcgccggtg gcgattaccg gtgcgctgct
    22801 ggtgggcctg ggcttcaaac cgttatacgc ggcggggctg tgtctgattg ccaacactgc
    22861 gccggtggcg tttggtgcgt tgggcgtgcc gattctggtc gccggtcagg taacgggaat
    22921 cgatccgttc cacattggcg caatggcggg acgtcagtta ccgttcctgt cggttcttgt
    22981 gccgttctgg ctggtagcaa tgatggacgg ctggaaaggg gtgaaagaga cgtggccagc
    23041 ggcgctggtt gctgggggaa gcttcgctgt cacgcagttc tttacctcta actatattgg
    23101 tccggaactg ccggatatta cttcggcgct ggtgagtatc gtctcactcg ctttattcct
    23161 taaagtctgg cggccgaaaa ataccgaaac ggcaatcagc atgggacaat ccgcaggtgc
    23221 gatggtggtg aataaaccat cttctggcgg tcccgtgcct tcagaatata gtctggggca
    23281 aatcattcgt gcgtggtcac cgtttttaat cttaacggtg ctggtcacca tctggaccat
    23341 gaagccgttt aaagcgttat ttgctccggg cggcgcgttt tattcactgg tgattaattt
    23401 ccagatccct catttgcatc aacaagtgtt gaaagcggca cccattgtcg cccaaccaac
    23461 gccaatggat gcggtgttta aattcgaccc tctctcggct ggcggcaccg ctatttttat
    23521 tgcggcgatt atctctatct tcatcctcgg cgtgggcatc aagaaaggga ttggcgtctt
    23581 tgccgaaacg ctaattagtc tgaagtggcc gatattgtcg attggcatgg tgctggcgtt
    23641 cgccttcgtc accaactatt ccggcatgtc caccacgctg gcgctggtac tggcaggtac
    23701 aggcgtgatg ttcccgtttt tctcaccgtt tctcggctgg ctgggcgtat tccttaccgg
    23761 ctcggacacc tcctctaacg ccctgtttgg ttcactgcaa tcgaccacgg cgcagcaaat
    23821 caacgtctct gacactctgc tggtggcagc aaataccagc ggcggcgtaa ctggcaagat
    23881 gatttccccg caatctatcg ccgtggcctg cgccgcgacg ggcatggtgg gccgagaatc
    23941 tgaactgttc cgctacaccg tgaagcacag tctgatcttt gccagtgtga tcggcattat
    24001 cacgctgttg caggcgtatg tgtttaccgg gatgttagtt tcgtaagtta ataaagccgg
    24061 atgatcgtta atatcatccg gcttcgttta cattactctg tcttattaat ggaaaattat
    24121 ttcccgcttt attatccatg tggcaataat gtttcgcgtt cagataacct gctaaataat
    24181 taaaagcgtg agaacatctg tttttttatc acgcaaaaca agtcagtatt aattatgttc
    24241 gcttgatgag caaacaccgt tctatctgtt gcttttgcaa tcttaatcgt taaaactacc
    24301 aacaaattta tatagttacg ttgtgaaaag ttgttaattt tttgtttatt gaaatttcgt
    24361 aaaaataacc agccagacat cgaatagggg ttattcttat aaattt
//
LOCUS       DAPOXO010000078        23319 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.078, whole genome shotgun sequence.
ACCESSION   DAPOXO010000078 DAPOXO010000000
VERSION     DAPOXO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23319
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.078"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            215..1066
                     /locus_tag="ROH59_003734"
     CDS             215..1066
                     /locus_tag="ROH59_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDX4806170.1"
                     /translation="MLKYSKTPGIFKLEGNRLGRPYHRLPTLFTGNFDVIDSHLGSYF
                     LKKHRSNITLKKIGCEMDIINKNAELMVSQVGHLAFDIDRSLLLMLLGNFYGLESSLE
                     EAKSHNGFPTKTETRLKNRLALDICTLIFNLQTSGIALKLKLDSSTVITHWAYQLTFT
                     LAGDEESSFRILLDDAHTDFILNLIRHSEHSKPQQVAKSVNKPALIKEIIRSLPLTLN
                     VKIAELSMNVADLAQIKAGDILPISLGETFPVAIGQSELFSALIVEDKDKLFLSELAG
                     KNENNHE"
     gene            1059..1430
                     /locus_tag="ROH59_003735"
     CDS             1059..1430
                     /locus_tag="ROH59_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDX4806171.1"
                     /translation="MSKQEDILAGDFGLTDEVAPVAKSADAETLVTRLEDRFSDSMTL
                     LKRIPVTLTLEVSSVEIMLADLLNIDDDTVIELDKLAGEPLDIKVNNILLGKAEVVVV
                     NEKYGLRVLEFNTRDINDLAP"
     gene            1427..2179
                     /gene="fliP"
                     /locus_tag="ROH59_003736"
     CDS             1427..2179
                     /gene="fliP"
                     /locus_tag="ROH59_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538309.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDX4806172.1"
                     /translation="MKRRTQLTLGLALLALAPLALAQGGDIALLNVVTHGNTQEYSVK
                     IQVLILMTLVGLLPTMVLMMTCFTRFIIVLSLLRQALGLQQTPPNRILIGIALSLTLL
                     VMRPIWLNIYDHAVVPFENDQITLTDALSTAATPLKRFMLAQTDKKAMAQIMTIGGAK
                     GNAADQDLSIVVPAYVLSELKTAFQIGFMIYIPFLVIDLIVASVLMAMGMMMLSPLIV
                     SLPFKLMLFVLIDGWSLTIGTLTTSIRGLGLG"
     gene            2182..2454
                     /gene="fliQ"
                     /locus_tag="ROH59_003737"
     CDS             2182..2454
                     /gene="fliQ"
                     /locus_tag="ROH59_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliQ"
                     /protein_id="HDX4806173.1"
                     /translation="MLTVDVAADIVASGIKVVILLVSVLVVPSLLVGLLVSVFQAVTQ
                     INEQTLSFLPRLIVTLVVLGVCGKWMIIQLHDLCIHLFTQAALLVH"
     gene            2456..3238
                     /gene="fliR"
                     /locus_tag="ROH59_003738"
     CDS             2456..3238
                     /gene="fliR"
                     /locus_tag="ROH59_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliR"
                     /protein_id="HDX4806174.1"
                     /translation="MRTSDVTQLMDLALGLWFPFVRIMAFLRYMPVLDNSALTARVRI
                     ILSLALAIIITPLIPHPIPHNLLSLNSLILTVEQILWGMLFGLMFQFLFLALQLAGQI
                     LSFNMGMSMAVMNDPSSGASTTVLAELINVYAILLFFAMDGHLLLVSVLYKGFTYWPI
                     GNALHPQTLRTIALAFSWVLASASLLALPTTFIMLIVQGCFGLLNRIAPPLNLFSLGF
                     PINMLAGLVCFATLLYNLPDHYLHLANFVLQQLDALKGHYGG"
     gene            3228..4367
                     /gene="flhB"
                     /locus_tag="ROH59_003739"
     CDS             3228..4367
                     /gene="flhB"
                     /locus_tag="ROH59_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HDX4806175.1"
                     /translation="MADSSSEEKTEKPSAQKLRKAREEGQLPRSKDMGLAASLFAAFV
                     VISSSFPWYADFVRESFISVHQYAQEINNPQVIGQFLRHHLLILGKFILTLLPMPAAA
                     LLSSLVPGGWLFLPKKILPDFSKISPLKGIGRLFSSEHLAETGKMTVKSVVVLVMLWV
                     SLRNNFAAFLSLQALPFKLAINDGLSLYASVMRNFVILFIFFALIDVPLAKALFTKGL
                     KMTKQELKEEYKNQEGKPEVKARVRRLQRQLAMGQIRKVVPKANVVITNPTHYAVALQ
                     YDQSRAAAPFVVAKGTDEIALYIRQVATENQVEVVEFPRLARSVYYTTQVNQQIPFQL
                     YRAIAHVLTYVLQMKHWREGAQPRPALNRHISIPKEVLKLDGENN"
     gene            4351..6444
                     /gene="flhA"
                     /locus_tag="ROH59_003740"
     CDS             4351..6444
                     /gene="flhA"
                     /locus_tag="ROH59_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDX4806176.1"
                     /translation="MAKTTKSFLALLRGGNLGVPLVILCILAMVILPLPPALLDILFT
                     FNIVLAVMVLLVAVSAKRPLEFSLFPTILLITTLMRLTLNVASTRVVLLHGHLGAGAA
                     GKVIESFGQVVIGGNFVVGFVVFIILMIINFIVVTKGAERISEVSARFTLDAMPGKQM
                     AIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGG
                     VCIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDV
                     RNQLLASPSVLYTATGIMFVLAVVPGMPHFPFLMFSALLGFTGWRMSKRPQAAEAEEK
                     SLETLTRTMTETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQV
                     ISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDG
                     VLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDI
                     TQLHNRLSSMAPRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVT
                     KDHILLAADVRLALRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQGGKVMLDS
                     VPVDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYN
                     EVPDELELKIMGALM"
     gene            complement(6664..7161)
                     /gene="rayT"
                     /locus_tag="ROH59_003741"
     CDS             complement(6664..7161)
                     /gene="rayT"
                     /locus_tag="ROH59_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="REP-associated tyrosine transposase RayT"
                     /protein_id="HDX4806177.1"
                     /translation="MSEYRRYYIKGGTWFFTVNLQNRRNQLLTTQFQTLRNAIINVKR
                     DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
                     IRNTQDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAEDVTDFSAG
                     ERIIL"
     gene            complement(7337..8086)
                     /locus_tag="ROH59_003742"
     CDS             complement(7337..8086)
                     /locus_tag="ROH59_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000093946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDX4806178.1"
                     /translation="MSSFLHGRFLHPGVFSLCVLLPLLASATTSHISFSYAARQRMQN
                     RARLLKQYQTHLKKQASYIVEGNAKSRRALRQHNREQIKQHPEWFPAPLKANDRRWQA
                     LAENNHFLSSNHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVFYAYNKILE
                     AKLPRTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRT
                     GETIRVSRLAEPFWQDHFLGARRILTEETIL"
     gene            8398..9138
                     /locus_tag="ROH59_003743"
     CDS             8398..9138
                     /locus_tag="ROH59_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HDX4806179.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(9109..9876)
                     /locus_tag="ROH59_003744"
     CDS             complement(9109..9876)
                     /locus_tag="ROH59_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HDX4806180.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(10081..10659)
                     /gene="lpcA"
                     /locus_tag="ROH59_003745"
     CDS             complement(10081..10659)
                     /gene="lpcA"
                     /locus_tag="ROH59_003745"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HDX4806181.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            10899..13343
                     /gene="fadE"
                     /locus_tag="ROH59_003746"
     CDS             10899..13343
                     /gene="fadE"
                     /locus_tag="ROH59_003746"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HDX4806182.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALTKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            complement(13386..13832)
                     /gene="ivy"
                     /locus_tag="ROH59_003747"
     CDS             complement(13386..13832)
                     /gene="ivy"
                     /locus_tag="ROH59_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ivy family C-type lysozyme inhibitor"
                     /protein_id="HDX4806183.1"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            14013..14783
                     /gene="yafV"
                     /locus_tag="ROH59_003748"
     CDS             14013..14783
                     /gene="yafV"
                     /locus_tag="ROH59_003748"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HDX4806184.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESDSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNERVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAI
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMMALREYREKFPAWQDADEFTFR"
     gene            complement(14882..14958)
                     /locus_tag="ROH59_003749"
     tRNA            complement(14882..14958)
                     /locus_tag="ROH59_003749"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14922..14924),aa:Asp,seq:gtc)
     gene            complement(15091..15822)
                     /gene="dnaQ"
                     /locus_tag="ROH59_003750"
     CDS             complement(15091..15822)
                     /gene="dnaQ"
                     /locus_tag="ROH59_003750"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HDX4806185.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGETTIQRIVRQASKLRVVFAT
                     DEELAAHEARLDLVQKKGGTCLWRA"
     gene            15887..16354
                     /gene="rnhA"
                     /locus_tag="ROH59_003751"
     CDS             15887..16354
                     /gene="rnhA"
                     /locus_tag="ROH59_003751"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HDX4806186.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCKVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            complement(16351..17073)
                     /locus_tag="ROH59_003752"
     CDS             complement(16351..17073)
                     /locus_tag="ROH59_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414749.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDX4806187.1"
                     /translation="MKPARVPQTVVAPDCWGDLPWGELYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     gene            17107..17862
                     /gene="gloB"
                     /locus_tag="ROH59_003753"
     CDS             17107..17862
                     /gene="gloB"
                     /locus_tag="ROH59_003753"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HDX4806188.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAISANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTPSQMYQSLRKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     gene            17934..19292
                     /gene="mltD"
                     /locus_tag="ROH59_003754"
     CDS             17934..19292
                     /gene="mltD"
                     /locus_tag="ROH59_003754"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HDX4806189.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(19341..20111)
                     /locus_tag="ROH59_003755"
     CDS             complement(19341..20111)
                     /locus_tag="ROH59_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDX4806190.1"
                     /translation="MTTQSHHDHVEKQFSSQASEYLTSTVHASGQDLQRLAVRLADYP
                     DASVLDMGCGAGHASFVAAQNVSTVVAYDLSAHMLDVVAQAAEARQLKNITTRQGYVE
                     SLPFADNAFDIVISRYSAHHWHDVGAALREVNRVLKPGGLLIVMDVMSPGHPVRDIWL
                     QTVEALRDTSHIRNHASGEWLTLISEANLIVDNLITDKLPLEFSSWVARMRTPEALVD
                     AIRIYQQSASTEVKTYFALQNDGSFTSDIIMLEAHKAA"
     gene            complement(20189..20989)
                     /locus_tag="ROH59_003756"
     CDS             complement(20189..20989)
                     /locus_tag="ROH59_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDX4806191.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            21230..22144
                     /locus_tag="ROH59_003757"
     CDS             21230..22144
                     /locus_tag="ROH59_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4806192.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIACSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELIADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(22141..22944)
                     /gene="dkgB"
                     /locus_tag="ROH59_003758"
     CDS             complement(22141..22944)
                     /gene="dkgB"
                     /locus_tag="ROH59_003758"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HDX4806193.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVKTALELDYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELHITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHSIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRENLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
     gene            complement(23107..23183)
                     /locus_tag="ROH59_003759"
     tRNA            complement(23107..23183)
                     /locus_tag="ROH59_003759"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23147..23149),aa:Asp,seq:gtc)
BASE COUNT         5640 a         5906 c         6103 g         5670 t
ORIGIN      
        1 gcctgatgcg acgctgcgcg tcttatcagg cctacagttt gtgcaatgtt ttatgacgat
       61 gcccgatatc tcgcccgtta ataatttaat tattttttca ccctattaat aatttgcccc
      121 tttcactccc cctctattta atacctcacc ttatgtcacc gccggatttg cgtgcacaga
      181 aacgcccata ccattacagc agagaaagta agccatgctg aagtacagta aaacgccagg
      241 catctttaaa ttagaaggta atcggcttgg acgcccctac catcgcctgc cgaccctgtt
      301 tacggggaat tttgatgtaa ttgattcgca tcttggcagc tactttctca aaaagcatcg
      361 cagcaatatc accctaaaaa agattggctg cgaaatggat attattaata aaaatgccga
      421 gctgatggtt tcccaggtcg ggcatctggc gtttgatatt gatcgctcct tgctgttaat
      481 gctgctgggc aatttttatg gtctggagtc gtctcttgaa gaagcgaaat cacacaatgg
      541 attcccgacc aaaacggaaa cacgtttaaa aaaccgcctc gcgctggata tctgcacgct
      601 gatttttaat ctgcaaacct ccggtattgc gctgaaatta aaactggaca gcagcacggt
      661 aattacccac tgggcgtatc aattaacctt tacccttgcg ggcgatgaag agagcagttt
      721 tcgtattttg ctcgacgacg cccacaccga ttttattttg aatctgatcc gccacagcga
      781 gcacagtaaa ccgcagcagg tggcgaaatc cgttaataaa ccggccctga ttaaagaaat
      841 catccgctcc ctgccgctga ccctgaacgt caaaatcgcc gagctatcga tgaatgtcgc
      901 ggatctggca cagattaaag ccggggatat tttacccata tcactgggag aaacgttccc
      961 ggtggcgatt gggcaatctg aattatttag cgccctgatt gtggaagaca aagacaaact
     1021 gtttttgtcg gagctggcgg gaaaaaatga gaacaaccat gagtaagcaa gaagatattt
     1081 tagccgggga ttttggcctc accgatgaag ttgcgcctgt cgccaaatcc gccgacgccg
     1141 aaacgctggt cacccgcctg gaagaccgat tttccgactc gatgacgcta ctgaaacgca
     1201 ttccggtgac cttaacgctg gaagtatcgt cggtggaaat catgttagcc gacctgctta
     1261 acatcgacga cgacacggtg attgaactgg ataaactcgc cggggagccg ctggatatta
     1321 aagtgaacaa tatcctgctg ggcaaagcgg aagtggtggt ggtcaacgag aagtacggcc
     1381 tgcgcgtgct ggaatttaac acccgcgata tcaacgacct ggcgccatga aacgccgcac
     1441 tcaactgacg ctgggcctgg cgctgctggc gctcgccccg ctggcgctgg cccagggcgg
     1501 cgatatcgca ctgcttaacg tggtcaccca cggcaacact caggagtaca gcgtcaaaat
     1561 tcaggtactg attctgatga ccctcgtcgg tttgctgccg acgatggtgc tgatgatgac
     1621 ctgtttcacg cgttttatta tcgtgctgtc actgctgcgc caggcgctgg ggctgcaaca
     1681 aacgccgcca aaccgcattc tgattggtat tgcgctctca ctcaccctgc tggtaatgcg
     1741 ccccatctgg ctcaatattt acgaccacgc ggtagtgccg ttcgaaaacg atcagattac
     1801 cctgaccgat gcgttaagca ccgccgcgac gccgctaaaa cgctttatgc tggcgcagac
     1861 cgacaaaaaa gcgatggcgc aaatcatgac catcggcggc gcgaagggca atgccgccga
     1921 ccaggatctc tccatcgtgg tgcccgccta tgtactgagc gagctgaaaa ccgccttcca
     1981 gattggcttt atgatttaca tcccgtttct ggttatcgac ctgattgtcg ccagcgtatt
     2041 gatggcgatg gggatgatga tgctgtcgcc gctgattgtt tcgctaccct ttaaactgat
     2101 gctgtttgtg ctgattgacg gctggtcgct gaccatcggc acgctcacca ccagcattcg
     2161 cgggctgggg ctgggctgat tatgttgacc gtagacgtcg ccgccgacat tgtcgccagc
     2221 ggcattaaag tagtgatttt gctggtttcg gtactggtgg tgccaagcct gctggtcggc
     2281 ctgctggtga gcgtgttcca ggcggtgacg cagattaacg aacagaccct gagctttttg
     2341 ccaaggctga ttgtcacgct ggtggtgctg ggcgtgtgcg gcaaatggat gattatccag
     2401 ttgcatgatc tctgcattca cctgtttacc caggccgcgt tgctggttca ttgagatgcg
     2461 cacaagcgac gttacgcaac tgatggatct ggcgctgggg ctgtggtttc ccttcgtgcg
     2521 cattatggcg tttctgcgct atatgccggt gctggataac agcgccctga ccgcgcgcgt
     2581 gcggattatt ttgtcgctgg cgctggcgat catcatcacg ccgttgatcc cccatcccat
     2641 tccccacaat ctgctatcgc tcaacagcct gatcctgacg gtggagcaaa ttttatgggg
     2701 catgttattc gggctgatgt ttcagttttt gtttctggcg ctacaactgg ccgggcaaat
     2761 tctctcgttc aatatgggga tgagcatggc ggtgatgaac gacccgagca gcggcgcatc
     2821 gaccaccgtg ctggcggagc taatcaacgt ctacgcgatc ctgctgtttt ttgccatgga
     2881 cgggcatctg ctgctggtaa gcgtgttgta caagggcttc acctactggc cgattggcaa
     2941 cgccctgcat ccgcaaaccc tgcgtaccat cgcgctggcc tttagctggg tgctggcgtc
     3001 ggcatcgctg ctggcgctgc cgaccacttt tatcatgctg attgtgcagg gctgctttgg
     3061 cttgctcaac cgtattgcgc cgccgctgaa ccttttttct cttggctttc cgatcaacat
     3121 gctggcgggg ctggtctgtt ttgccaccct gctctacaac ctgccggatc actatctgca
     3181 tctggcgaat tttgtcttac aacaactcga cgcgctgaaa ggtcactatg gcggatagca
     3241 gcagcgaaga aaaaacagag aaaccctcgg cgcaaaagct gcgtaaagcg cgtgaagagg
     3301 ggcaactgcc gcgctcgaag gatatggggc tggcggcgag cctgtttgcg gcgtttgtgg
     3361 tgatctccag cagttttccg tggtatgccg attttgtgcg cgagagcttt atcagcgtgc
     3421 atcagtatgc gcaggagatt aataacccgc aggtgatcgg ccagtttctg cgccatcacc
     3481 tgttaattct cggcaagttt atcctcacct tgctgccgat gcctgctgcc gcgctgctct
     3541 cttcgctggt gcccggcggc tggctgtttc tgccaaaaaa aatcctcccg gatttcagca
     3601 aaatcagtcc gttaaaaggc attgggcggc tgttttccag tgaacatctg gcggaaacgg
     3661 gaaagatgac ggtgaagtct gtggtggtgc tggtgatgct gtgggtaagc ctgcgcaata
     3721 actttgccgc ctttctcagc ctgcaggcgc tgccgttcaa actggcgata aatgacggtt
     3781 tatcgctcta cgccagcgtg atgcgcaact ttgtcattct gtttatcttc ttcgcgctta
     3841 tcgacgtgcc gctggcgaaa gccctgttca ccaaagggct gaagatgacc aaacaggagc
     3901 tgaaagaaga gtacaaaaat caggaaggta agccggaagt gaaggcgcgt gtgcggcgac
     3961 tgcaacggca actggcgatg gggcaaatcc gcaaagtggt gccgaaagcc aacgtggtga
     4021 tcaccaaccc gacccactac gccgtggcgt tacagtatga ccagtcgcgc gccgccgcgc
     4081 cgtttgtggt ggcaaaaggc accgatgaaa tcgccctcta tattcgccag gtcgccacgg
     4141 agaatcaggt ggaagtggtc gagttcccgc ggctggcacg ctcggtttac tacaccaccc
     4201 aggtgaacca gcaaattccg tttcagcttt accgggccat cgcccacgtt ctgacctacg
     4261 tcctgcaaat gaaacactgg cgcgagggcg cacagccgcg cccggccctg aacagacata
     4321 tttccattcc caaagaggtg cttaaactgg atggcgaaaa caactaaatc gttccttgcg
     4381 ctgctgcgcg gcggcaatct cggcgtgccg ctggtcatac tgtgtattct ggcgatggtt
     4441 attctgccgc tgccgcctgc gctgctggat attctgttca ccttcaacat tgtgctggcg
     4501 gtgatggtac tgctggtggc ggtgtcggcg aaacgaccgc tggaattcag cctgttcccg
     4561 accattttgc tgatcaccac cttaatgcgc ctgacgctta acgtcgcctc tacgcgcgtg
     4621 gtgctgttgc acgggcatct cggcgcgggc gcggcgggta aggtgataga gtcgtttggt
     4681 caggtggtga tcggcggcaa ctttgtcgtc ggtttcgtgg tgtttatcat cctgatgatc
     4741 atcaacttta tcgtcgtcac caaaggggcc gagcgtattt ccgaggtttc tgcccgcttt
     4801 accctggacg cgatgcccgg caaacagatg gcaattgacg ccgatcttaa tgccgggttg
     4861 atcaaccagg cacaggcgca gacccggcgc aaagatgttg ccagcgaggc cgatttttac
     4921 ggcgcgatgg acggggcatc gaagtttgtg cgcggggatg ccatcgccgg gatgatgatt
     4981 ctggcgatca acctgatcgg cggcgtctgt attgggatct tcaaatacaa cctgagcgcc
     5041 gatgctgcct tccagcaata tgtgttgatg accatcggcg acggcctggt ggcgcagatc
     5101 ccttccctgc tgctctccac cgcggcggcg attatcgtca cccgcgtcag cgacaacggc
     5161 gatatcgccc atgacgtgcg taatcagttg ctggcaagcc cgtcggttct ctacaccgcc
     5221 actggaatta tgttcgtgct ggcggtggtg ccgggaatgc cgcatttccc gttcctgatg
     5281 ttcagcgccc tgcttggttt taccggctgg cggatgagca agcgcccgca agcggcggag
     5341 gcggaagaga aaagcctcga aacgctaacc cgtacgatga cagaaaccag cgagcaacag
     5401 gtcagttggg aaactattcc gctgatcgaa cctatcagtt taagcctcgg ctacaaactg
     5461 gtggcgctgg tggataaagc gcagggtaat ccgctcaccc agcggattcg cggtgtacgg
     5521 caggtgatat ccgacggtaa cggagttctg ctgccggaga tccgtattcg ggaaaacttc
     5581 cgcctcaagc ccagccagta cgccattttc atcaacggca ttaaggctga tgaagcggat
     5641 attccggcgg ataaactgat ggccctgccc tccagcgaaa cctacggcga gattgacggc
     5701 gtactgggga atgacccggc gtacgggatg ccggtcacct ggattcaacc cgcgcagaaa
     5761 gcgaaggcgc tgaatatggg gtatcaggtg atcgacagcg ccagcgtgat tgccacccat
     5821 gtgaataaga ttgtgcgcag ctatattcct gacctcttta actatgacga tattacgcag
     5881 ctgcataacc gtttgtcgtc gatggcaccg cgactggcgg aagatttgag cgcggcactc
     5941 aattacagcc agttgctgaa agtgtaccgg gcgctactga ctgaaggcgt ttccctgcgc
     6001 gatatcgtca ccatcgccac cgtgctggtc gccagtagtg cggtgaccaa agatcatatt
     6061 ctgctggcgg cagatgtgcg cctggcgctg cggcgcagca ttacccatcc gttcgttcgc
     6121 aagcaggagc tgacggtgta tacgctgaat aatgagctgg aaaatctgct gaccaacgtg
     6181 gtgaatcagg cgcaacaggg cgggaaagtg atgcttgata gcgtgccagt ggacccgaat
     6241 atgctcaacc agttccagag cacgatgcct caggtgaagg agcagatgaa agcggcgggg
     6301 aaagatccgg tgctgctggt gccgccgcaa ctgcgcccct tgctggcgcg ctacgcaagg
     6361 ttgtttgcgc cggggctgca tgtgctgtcg tataacgaag tgccggatga gctggagttg
     6421 aagataatgg gggcgttgat gtaggcatcc ggcatcggtg catattgccg gatgcggcgt
     6481 gaacgcctta tccggcctac gggtgagcac ggttttgtcg gcatgataag acgcgtagcg
     6541 gcgcatctgg caccggtgca caactgccgg atgcggcgtg aacgccttat ccggcctacg
     6601 ggtgagcgcg gttttgtcgg catgataaga cgcatctgcg tcgcatcagg catcggcgca
     6661 cagctataaa atgatacgct ccccagcact aaaatccgtt acgtcctccg cccaatcgat
     6721 gggatataac cctcgcgcga catcgcgatg aaacgttgag aatggccaat cactcacttg
     6781 ctttacccaa ccatgtttta ctggatttat ataaatataa tcaacatgat ggcgatagtc
     6841 ttgggtattg cgaatggcat gctcccaaaa acgcggttgc cagatatttt tcaatccaca
     6901 agcatgggta aattgctttt taatttcccg ccagcgcgag gaaaaatcat catcgccttc
     6961 aggtaatgtc catatgcaat gcatatgctc cggcaaaact acccaagcgt taatttcaaa
     7021 aggtctgtct cgcttaacgt taataatagc gttacggagc gtctgaaact gggtggtcaa
     7081 aagttggttt cgacgattct gtaaatttac cgtgaaaaac caggttcccc ccttgatgta
     7141 ataacgacga tattcagaca taacgactcc tttttctcaa cggtaagaag aaaaggaaaa
     7201 gtcggcaatg atgttgtgtt aaatcgggaa agcggctcgc aaaaaatgca cagatttata
     7261 ggcatgataa gacgcgtagc gtcgcatcag gcaccggtac acaaccgccg gatgcggcgt
     7321 gaacgcctta tccggcctac aaaatcgtct cttccgtcaa aatccgccgc gcgcccaaaa
     7381 aatgatcctg ccagaaaggt tcagctaacc gacttacccg aatggtttcc ccggtgcgcg
     7441 gtgactcgat aaactgaccg tctccaagat atacgcccat atggtcggct atctcacggc
     7501 tgtggatatg gaaaaacagc aaatctcccc ggcgcaggtc gttattcgcc acaatcgttg
     7561 cccgacggta gtggtacatc tcattggccg tgcgcgggag cttagcctca aggatcttgt
     7621 tgtaggcata aaaaaccaac ccgctacagt cgaaaccttt atcaggccgc gtgccccccc
     7681 agacataagg cttgccaagt tgctgttcca ggcggtgaat cgccacttcg gtgatgttat
     7741 gcaggtggtt gctgctgagg aaatgattgt tttccgccag cgcctgccag cgtctgtcgt
     7801 tcgccttgag cggcgcagga aaccattctg gatgctgttt tatctgctcc cgattatgct
     7861 ggcgcagcgc ccttctgctt ttagcattgc cttccacaat atagctggcc tgctttttca
     7921 gatgggtttg gtactgtttt aataaacgcg cacggttttg catccgctgg cgggcggcgt
     7981 agctaaaaga gatatgtgat gtggtggcgc tggcgagtaa agggagcaaa acgcataacg
     8041 aaaacacgcc tggatgcaga aatctgccgt gcaagaacga agacatgaag gacataaacc
     8101 agctgaatga aggtgagaat tttaaaagac cggaggagta aacgggatta ttaattgctt
     8161 atttgcatat tactattgcg gtttcataat cttaggaaat aagaaataaa tctacaatcc
     8221 atgcgctttt cggactcttg aaaactgcac ctgtgctaaa tttgtaaacc ctgcgccgac
     8281 aggcttgcgt aaaactcttt tggtgataat gtgagccttc caaatccaga ctattccgat
     8341 ttgggattca ttttgccgtc ctggcgtgtg taaccgtttt atcaaggaat aagcagtatg
     8401 cgtaaaatcg cattaattct tgcgatgttg ttgatcccat gcgtttcgtt tgccggtttg
     8461 ctgggcagca gtagctcgac cacgccagtg agcaaagagt ataagcagca gttgatggga
     8521 tcccctgtct acatccagat cttcaaggaa gaacgtacgc tcgatctcta cgtcaaaatg
     8581 ggcgagcaat atcaactgct cgacagctat aaaatctgta aatattccgg cggcttaggg
     8641 ccaaaacagc gtcagggcga tttcaaaagc ccggaagggt tttatagcgt ccagcgtaat
     8701 cagttaaaac cagacagccg ttactacaaa gcgattaata ttggattccc aaacgcctat
     8761 gaccgtgcgc atggttatga agggaaatac ctgatgattc acggcgattg tgtttccatc
     8821 ggctgctacg cgatgaccaa tcagggtatt gatgagatct tccagttcgt tactggtgcg
     8881 ctggtgtttg gtcagccgag cgtgcaagtg agtatttatc cgttccgcat gaccgacgcc
     8941 aatatgaagc gccataaata ttccaacttt aaggacttct gggagcaact gaagccgggc
     9001 tacgactact ttgagcaaac ccgtaagcca ccgaccgttt ctgtggtcaa tggccgttac
     9061 gtggtcagca agccgttaag ccacgaagtt gtgcagccac aactggcatc aaactacacg
     9121 ctccccgagg caaaataagc gccattcacc tggcataatc ttttgccagg tttcattgcc
     9181 cgtcagcggc tgtgtcgcaa tcaccgtgac cacatcattc ggtgtggtct gcgagctgaa
     9241 gtcgatttcc acatcctgat ccagcaacgt tgccacgcca aacggcgcgc ggcgggtgat
     9301 ccagtgtaaa ttagtcgagc aatacgccat tacatagcgc ccgtcagaaa gcagcatgtt
     9361 gaaaacgccc ttctgccgca gttcatccgc cagtgaggcg atatatttaa acactgccgc
     9421 catgttgccc ggtgtgcgcg ggtaacgctg cgttaattta tgcaggagcc agcaaaaggc
     9481 tttttcgcta tcggtttcac cgaccgggcg gaagttgccg gtttccagtg atttgtagcc
     9541 cgtcagttgt ccattatggg cataagtcca gttacgcccc cataactcgc gggtaaacgg
     9601 gtgagtattt tccagcgcca cctcgccccg attagcctgg cgaatatgag ccaccaccga
     9661 acaggatttt atcgggtagt cctggacaag tttggcgatg ggggaattaa agctgggttg
     9721 cggatcttta aatgtgcgac agcctttacc ttcgtaaaag gtaatgcccc agccatcttt
     9781 atgtggcccg gttccaccac cacgctgtac aagtccggtg aaactaaagc agatatcggt
     9841 agggacgttg gcactcatcc cgagcaattc gcacatgggt aacctccaca acagcgggag
     9901 cgcatggccc ccggcgaaga ttgatttaag aattttcagg tcggatgtgg cgtgaacgca
     9961 ttattcggcc tacggttcgg gtgcagattg taggcatgat aagacgcgtc agcgtcgcat
    10021 caggcatcag agcacaaatg ccggatgcgg cgtaaacgcc ttatccggcc tacgccagac
    10081 ttacttaacc atctcttttt caattaactg gatcaggata tggatcactt taatgtggat
    10141 ctcctgaatg cggtcggcat aaccaaagtg cggtacgcga atttcgatat ccgccgtgcc
    10201 agccattttg ccgccgtctt taccggtcag ggtgatcact ttcatcccct tctcacgcgc
    10261 cgccgcgatc gctttgatca cgtttgcaga gttaccggag gtggagatcc ccagcagtac
    10321 atcgccttcg cgacctaccg cttcaacgta acgggagaaa atatcattga aaccaaaatc
    10381 gttaccgacg caggaaatat gactaacgtc agaaatggca atcgccgggt agcccggacg
    10441 gttttcacgg tagcgaccgg tcaactcttc ggcaaagtgc atggcgtcgc aatgggagcc
    10501 gccgttgcca caggaaagca ctttgccacc ggctttaaag ctgtctgcta acaggaccgc
    10561 cgcgcgctga atggcgtgaa tattggcgtc atcttttaaa aagttagcca gcgtttccgc
    10621 cgcttcgttc agttcattac gaataagatc ctggtacatg aggatatcct tcagcataaa
    10681 tgtaatagac aaaatgcagt gtaccggata ccgccaaaag cgagaagtac gggcaggtgc
    10741 tatgaccagg actttttgac ctgaagtgcg gataaaaaca gcaacaatgt gagctttgtt
    10801 gtaattatat tgtaaacgca ttgctaaatg tttttacatc cactacaacc atatcatcac
    10861 aagtggtcag acctcctaca agtaaggggc ttttcgttat gatgattttg agtattctcg
    10921 ctacggttgt cctgctcggc gcgttgttct atcaccgcgt gagcttattt atcagcagtc
    10981 tgattttgct cgcctggaca gccgccctcg gcgttgcggg tctgtggtcg gcgtgggtac
    11041 tagtgcctct ggccattatc ctcgtgccat ttaactttgc gcctatgcgt aagtcgatga
    11101 tttccgcacc ggtatttcgc ggtttccgta aggtgatgcc gccgatgtcg cgcactgaga
    11161 aagaagcgat tgatgcgggc accacctggt gggagggcga cttgttccag ggcaagccgg
    11221 actggaaaaa gctgcataac tatccgcagc cgcgcctgac cgctgaagag caagcgtttc
    11281 tcgacggtcc ggtagaagaa gcctgccgga tggcgaatga tttccagatt actcatgagc
    11341 tggcggacct gccgccggag ttgtgggcgt accttaaaga gcatcgtttc ttcgcgatga
    11401 tcatcaaaaa agagtacggc gggctggagt tctcggctta tgcccagtct cgtgtgctgc
    11461 aaaaactctc cggcgtgagc gggatcctgg caattaccgt cggcgtgccg aactcattag
    11521 gcccgggcga gctgctgcaa cattacggca ctgacgagca gaaaaatcac tatctgccgc
    11581 gtctggcgcg tggtcaggag atcccttgct ttgcactgac cagccccgaa gcgggttccg
    11641 atgcgggcgc gattccggat accgggattg tctgcatggg cgaatggcag ggccagcagg
    11701 tgctggggat gcgtctgacc tggaacaaac gctacattac gctggcaccg attgcgaccg
    11761 tgctgggtct ggcgtttaaa ctctccgacc cggagaaatt actcggcggt gcagaagatt
    11821 taggtattac ctgtgcgctg atcccgacca ccacgccggg cgtggaaatt ggtcgtcgcc
    11881 acttcccgct gaacgtaccg ttccagaacg gaccgacgcg cggtaaagat gtgttcgtgc
    11941 cgatcgatta catcatcggc gggccgaaaa tggccgggca aggctggcgg atgctggtgg
    12001 agtgcctctc ggtaggccgc ggcatcaccc tgccttccaa ctcaaccggc ggcgtgaaat
    12061 cggtagcgct ggcaacgggt gcgtatgcgc acattcgccg tcagttcaaa atttctattg
    12121 gtaagatgga agggattgaa gagccgctgg cgcgtattgc cgggaacgcc tacgtgatgg
    12181 atgctgcggc atcgctgatt acctacggca ttatgctcgg tgaaaaaccc gccgtgctgt
    12241 cggctatcgt taagtatcac tgtacccacc gcgggcagca atcgattatc gacgcaatgg
    12301 atatcaccgg gggtaaaggc attatgctcg ggcagagcaa cttcctggcc cgtgcttacc
    12361 agggggcacc gattgccatc accgttgaag gggcaaatat tctgacccgt agcatgatga
    12421 tcttcggtca gggggcgatt cgttgccatc cgtacgtgct ggaagagatg gaagcggcga
    12481 agaacaatga cgtaaacgcg ttcgataaac tgctgttcaa acatatcggt cacgtcggta
    12541 gcaacaaagt tcgcagcttc tggctgggcc tgacgcgcgg tttaaccagc agcacgccaa
    12601 ccggcgatgc cactaaacgc tactatcagc acctgaaccg cctgagcgcc aacctcgccc
    12661 tgctttctga tgtctcgatg gcggtgctgg gcggcagcct gaaacgtcgt gagcgcatct
    12721 cagcccgtct gggggatatt ttaagccagc tttacctcgc ctctgccgtt ctgaagcgtt
    12781 atgacgacga aggccgtaat gaagccgacc tgccgctggt gcactggggc gtacaggatg
    12841 cgctgtatca ggcagaacag gcgatggacg atttactgca aaacttcccg aaccgcgtgg
    12901 ttgccgggct gctgaatgtg gtgatcttcc cgaccggacg tcattatctg gcaccgtctg
    12961 acaagctgga tcataaggtg gcgaagattt tacaagtgcc gaatgccacc cgttcacgta
    13021 ttggtcgcgg tcagtacctg actccaagcg agcataaccc ggttggttta ctggaagagg
    13081 cgttggtgga tgtgattgcc gccgacccga ttcatcagcg gatctgtaaa gagctgggta
    13141 aaaatctgcc atttacccgt ctggatgaac tggcgcacaa cgcgctgacg aaggggctga
    13201 ttgataaaga tgaagccgct attctggtga aagctgaaga aagccgtctg cgtagtatta
    13261 acgttgatga ctttgatcca gaagagctgg cgacgaagcc ggtaaagttg ccggagaaag
    13321 tgcggaaagt tgaagccgcg taattgaata acggagccga aaggctccgt ttttttatcg
    13381 gctaattatt taaaattaaa gccatccgga tggttttcca ggctgccggt caacgccgcg
    13441 aacagcaccg ttttgccatc aatcgaaagc gcatcattca cattcagcca ggtgagtttc
    13501 tcttgcgacg ttttctcatc aatagtcgag aacagccccg tcatctgatt agatttctcg
    13561 gaccacatca cagcgatacg ttgcgagcca cagtcatgag gtttgcacgc gctcatcacc
    13621 tgatacgtct catctcccaa tgtcacggtt tgtgcgggag tataagtacc gcctttcatc
    13681 acccaggcag gcagcttatg cccttgcacc atctgattaa acgccgcttt ggtggtttcg
    13741 ccctttgcaa gactgctaat ggttaaatca tcctgcgcca ttgcactggt ggcgatgacc
    13801 agagcggcga ctgtcgttat tgccttaaac atcattcctc ccgggcttat cctgcccatg
    13861 tgattaactc cctaaagcct ggcgataaca cgataatttg caaatcagat atttccaata
    13921 tcagcatttg ttatcaattt attctgcgct aaggcaactg cctgataagg tgttagagtt
    13981 ataaaaccct tcgcataaag gagttgtaca ccgtgcctgg tttgaagatt acgcttttgc
    14041 agcaaccact ggtgtggatg gatggtcctg ccaacctgcg ccattttgat cgtcaactgg
    14101 aaggtattac cgggcgcgat gtgatcgttc taccggagat gtttaccagc ggctttgcca
    14161 tggaagcggc agcttcgtcg ctagcacaag atgacgtagt gaactggatg accgctaaag
    14221 cgcagcagtg caatgcgctg attgcaggca gtgttgcatt acaaacggag tctgattcgg
    14281 ttaaccgctt tttgctggtt gagccgggcg gcacggtaca tttttatgat aagcgtcatc
    14341 tgttccgcat ggcagatgag catctgcatt ataaagcagg caatgagcga gtgattgtgg
    14401 aatggcgcgg ctggcgtatt ttaccgctgg tgtgctacga cttacgtttt ccggtgtggt
    14461 cgcgcaatct caacgattat gacctcgcca tctacgttgc caactggcct gcaccgcgct
    14521 ctctgcactg gcaggcatta ctgacagccc gcgcgattga gaatcaggcg tatgtagcgg
    14581 gatgtaatcg cgtcggcagc gatggcaacg gctgccatta tcgcggtgac agccgggtga
    14641 ttaatccaca aggcgagatt atcgctactg ccgacgcgca tcaggcaacg cgcattgatg
    14701 cggagctatc gatgatggca ttgcgggaat atagagaaaa gtttccggca tggcaggatg
    14761 cggatgagtt cacatttcgt tagagggtga atatggctac gagataagtt tcgtggctat
    14821 ttttctctgg aacttaaacg acgaaatccc gaatcagtaa tgattcgggc tttctgaata
    14881 ttggcggaac ggacgggact cgaacccgcg accccctgcg tgacaggcag gtattctaac
    14941 cgactgaact accgctccgc gttgtgttcc gttgggaacg aggcgaatat tacggattgc
    15001 ctcacccttc gtcaacggtt tttctcatct tttgaatcgt ttgctgcaaa aatcgcccaa
    15061 gtcgctattt ttagcgcctt ttacaggtat ttatgcccgc cagaggcagg ttccgccctt
    15121 cttctgcacc agatcaagac gggcttcatg tgctgcaagc tcttcatctg tcgcaaaaac
    15181 aacgcgtaac ttacttgcct gacgcacaat gcgctgaatt gttgtttcac cttgttgctg
    15241 ttgtgtctct ccttccatcg caaaagccat cgacgtttga ccaccggtca tcgccagata
    15301 aacttccgca aggatctggg catcgagtaa tgccccatgc agcgttcgtt tactgttatc
    15361 tatttcgtag cgggcacata acgcatcgag gctgttgcgt ttaccgggaa acattttcct
    15421 cgccaccgca aggctatcgg tgaccttaca gaaggtattg gtcttcggaa tatcgcgctt
    15481 aagcaacgaa aactcgtagt ccataaagcc gatatcaaac gctgcgttat ggatcaccaa
    15541 ctccgcgccg cggatatagt ccatgaactc atcggctacc tcggcaaacg tgggcttatc
    15601 gagcaaaaat tcatcggcaa taccatgtac gccaaaggct tccggatcca ccagccgatc
    15661 gggtttgaga taaacatgga agttattgcc cgtcaggcga cggttcacca cttcaacggc
    15721 accaatctca atgatcttgt ggccttcata gtgcgcacca atctggttca taccggtggt
    15781 ttcagtatcg agaacgatct ggcgtgtaat tgcagtgctc atagcggtca tttatgtcag
    15841 acttgtcgtt ttacagttcg attcaattac aggaagtcta ccagagatgc ttaaacaggt
    15901 agaaattttc accgatggtt cgtgtctggg taatcctgga cctgggggtt acggcgctat
    15961 tttacgctat cgcggacgcg agaaaacctt tagcgctggc tacacccgca ccaccaacaa
    16021 ccgtatggag ttgatggccg ctattgtcgc gctggaggcg ttaaaagaac attgcaaagt
    16081 cattttgagt accgacagcc agtatgtccg ccagggtatc acccagtgga tccataactg
    16141 gaaaaaacgt ggctggaaaa cagcagacaa aaaaccagta aaaaatgtcg atctctggca
    16201 acgtcttgat gctgctctgg ggcagcatca aatcaaatgg gaatgggtta aaggccatgc
    16261 cggacacccg gaaaacgaac gctgtgatga actggctcgt gctgcggcaa tgaatcccac
    16321 actggaagat acaggctatc aagtcgaagt ttaagcctgt ggtttacgac attgccgggt
    16381 ggcaccaacc gcctggcgaa ttcgcggttt attcttgctc tgtttcatcg gatttagcgt
    16441 taaaggaata gtccgtttcc gggcaacaat aagttgtaag caaccaagcg caggaatatg
    16501 cgcattcaat agttttcctc cgtgtttgtt ccacgggaga acgtggaaac ggctggcgtg
    16561 tagcacttca aaattcaaca aagagagcca gtccagctgc cgcatcagag taaacatccg
    16621 gctgttatag ggcgatgttt tgcgcaatac cggcacaagt ttgcgtaatc ccattaaact
    16681 gatgggattg aagccactaa tcaccagcca accatcatca atcagtaccc gatcggcttc
    16741 acgcaataaa cgatgcggat cagtgcacca cggcaatgta tgtgccagta gacaaacatc
    16801 aacggattta tcggcaaaag gaagatgaag tgggtccgcc tgcacctgga cgggcattcc
    16861 ttgcgcagaa acattcactt gatgagaaac cgcgcacgct tcgcaattga tttctgcgct
    16921 taaattgcca atcttaagca gatgaaaacc atacatttta gtgaaccacg ggttgagctg
    16981 acgctccagc gccttgcgat aaagctctcc ccagggcaaa tcgccccagc aatcaggagc
    17041 cacgacagtt tgagggactc ttgccggttt catcacaacc ttccgtttca cactgagagg
    17101 taatctatga atcttaacag tattcccgcc tttgatgaca attacatctg ggttttgaat
    17161 gatgaagcag gtcgctgtct gattgtcgat cccggggacg cagagccagt attaaacgcc
    17221 atttccgcca ataactggca accggaggcc atatttctca cccaccatca ccacgatcac
    17281 gttggcggcg taaaagaact ggtggaaaag tttccgcaaa ttgtggtgta tggaccacaa
    17341 gagacacaag ataagggaac aacacaggta gtcaaagatg gcgaaactgc cttcgttttg
    17401 gggcatgaat ttagtgtaat tgccacaccg ggtcacactt taggacatat ctgttacttc
    17461 agtaaacctt atctattttg cggcgacacg ctgttttctg gtgggtgtgg tcggttgttt
    17521 gaagggacac catcacaaat gtatcaatca cttagaaagt taagtgcgtt acctgacgac
    17581 acattggtat gttgtgctca tgaatatacc ttatcaaata tgaagtttgc tttgagtatt
    17641 cttccgcacg atttgtccat aaatgattat tatcgtaaag ttaaggagtt acgggcaaaa
    17701 aatcaaataa cactacccgt aattctgaaa aatgagcggc aaattaatgt ttttttaaga
    17761 acggaagata ttgatttaat taatgtaatt aatgaagaaa cattattgca acaacctgaa
    17821 gaacgttttg catggttaag gtcaaagaaa gataggttct gataaaactt tcttgtcatc
    17881 ggctccgttc gccgttatga tcggtcgtct tttaagcaac tattgacaca cacatgaagg
    17941 caaaagcgat attactcgcc tctgtcctgc tcgtgggttg ccagagcacc ggcaacgttc
    18001 aacagcacgc acagagcctt tctgcagctg gtcaagggga agcagcaaag tttacaagtc
    18061 aggcacgatg gatggacgat gggacgtcta tcgcgccaga tggtgacttg tgggctttca
    18121 ttggcgacga gctaaagatg ggaattccgg aaaacgaccg gattcgcgaa cagaaacaga
    18181 aatatttacg caataagagc tatctccacg atgtaacttt acgggcagag ccgtatatgt
    18241 actggatagc cgggcaagtt aaaaaacgta acatgcctat ggaactggta ctactaccca
    18301 tagtggagag cgcttttgat cctcacgcaa cgtctggcgc caatgccgcg ggcatctggc
    18361 agatcattcc gagcacgggg cgcaattatg gtttgaaaca gacccgcaat tatgacgcgc
    18421 gtcgcgatgt tgttgcttca acaactgccg cgctgaacat gatgcagcgt ctgaacaaga
    18481 tgtttgacgg cgactggctt ctgaccgtag cggcttataa cagcggcgaa ggtcgggtca
    18541 tgaaggcaat taaaacgaac aaagcgcgtg ggaaatccac ggacttctgg tcgttaccgt
    18601 tgccgcagga aacgaagcag tacgtgccta aaatgctggc attgagtgat attctcaaaa
    18661 acagcaagcg ttatggcgta cgtctgccaa cgaccgatga aagccgtgct ctggcacgtg
    18721 tgcacctgag cagcccggtt gaaatggcga aggttgcaga tatggcgggg atttccgtca
    18781 gcaagctgaa gacattcaac gcaggcgtga aaggctccac gctgggcgca agtggtccgc
    18841 agtacgtgat ggtgccaaag aagcatgcag atcaactgcg tgaatctctg gcttcaggcg
    18901 aaattgctgc tgtacagtcg acgctggttg ccgacaatac gccacttaac agccgtgttt
    18961 acaccgtacg ctctggcgac acgctttcaa gtatcgcttc acgtctcggc gtaagcacca
    19021 aagatttgca gcagtggaac aaactgcgcg gatctaagct gaagccaggc caaagtttga
    19081 cgattggtgc aggcagtagc gcacagcgac tggcaaacaa cagcgatagc attacgtatc
    19141 gtgtgcgcaa aggcgattcg ctttcaagca ttgctaaacg ccacggcgtg aacatcaaag
    19201 atgtaatgcg ctggaacagc gacactgcga atctgcaacc aggcgataag ctgacgttgt
    19261 ttgtgaaaaa caacaacatg ccagattcct gacaaaccag ataataaaaa aggcaccgat
    19321 tcccccggtg ccttttttat ttatgccgct ttatgtgctt ctagcatgat gatatcactg
    19381 gtgaaagagc catcattctg caaggcaaaa tacgttttca cctctgtcga tgcgctctgt
    19441 tggtaaatgc gaatagcgtc tactaacgct tctggcgtac gcattctcgc tacccatgaa
    19501 gaaaattcca gcggtaactt atctgtaatt aaattatcaa ctatcagatt ggcttcactg
    19561 attaacgtca accactcacc gctggcgtgg ttccgtatgt gagatgtatc gcgtaatgct
    19621 tctaccgtct gtaaccagat gtcgcgcact gggtgacccg gagacattac gtccatcaca
    19681 atcagcagac caccgggttt caatacccgg ttcacttcac gcaatgctgc accaacatca
    19741 tgccaatgat gggcagaata acggctgata acaatatcaa atgcgttatc ggcaaatggc
    19801 aggctttcga cataaccctg gcgggtggtg atatttttca gttgccgggc ttcggcagct
    19861 tgtgccacga catccagcat atgggcagat aagtcatacg ccaccaccgt gctcacgttt
    19921 tgcgcagcga caaagctggc atgccctgct ccgcagccca tatcaagtac acttgcatca
    19981 ggataatcag ccagacgcac cgccagacgc tgtaaatctt gtccggatgc atgtacggta
    20041 ctggtcagat attcgctggc ttgagagcta aactgctttt ctacgtggtc atggtgggat
    20101 tgtgttgtca ttgcgctgtc cttttgttat ttgagtataa aagggcagcg ccaaacgttg
    20161 gtctgccctg tggcagacct gacatacctt atttatcagg cttgccggga ctgaattcaa
    20221 cgagtagcgg attgtgatcg gacgcgcgcg taaccagtac agaagcttcg ctgacgttca
    20281 gaccacggta gaaaacaaaa tcgagcgggc gaccaaacgc ccgacggcgc tgatcatcgg
    20341 taaaacgcac ctggcgcagc gacatttccc gcgcaaagcg atataacgcg ttcatccttc
    20401 tacggctcca ggcattgaaa tctcccgcca taatgaccgg gccactgtgg tgagctatct
    20461 gatcgccaat aggaagtaac tgcttactat agacatccac gcccagactg aagttgacgg
    20521 cgtgtatatt aaccaccatc aacaggcggg tgtcaggtaa cggatagacc gtcaccagtg
    20581 ccgacttcgc cagacgcaaa atgggttctc gttcacgtaa cgggcagcaa tacactggat
    20641 gtgccgccga aagggtcatt acgccagaag gatgttgtgg cagcacgaaa gcgggtacct
    20701 gatcggcggc aagatagtta gcagtcgcaa actgtactaa ctctggcgtt gtctgcgctt
    20761 cctgcaataa caccagatgt gcatctttgc cgtagttctt taataccgac aaccattcag
    20821 cgcgttgctg tttgtatatg ttccacacca ggatccgaat acgctcttcg gtacttaacg
    20881 gttctccagg tggtaatgcc tggccgatgc tcgcaaaaga ccccggcggt aagatccttt
    20941 ccgcaggttg tccggcaaca tagcgcatgg cataggtgtt ttttcgcact tttgactttg
    21001 aaacctctat cacgtcaacc cttccgcact cgggagggtt ctactgttat agggatttta
    21061 gctcactctt tcaacgagca attgtatatt gttatgtaag caagtgctta caccggtcag
    21121 gattttgctc attattgaga acattaaatc ggatggcata tctcgcatcc tgatggttta
    21181 atgacaaata aattcaaaat atctcttcta ttttgcaaca ggagcaaaaa tgaaagccac
    21241 gtcggaagaa ctcgccattt ttgtttcagt cgtcgaaagc ggcagcttta gccgggcagc
    21301 ggaacaatta gggcaagcaa actcagcggt aagccgggcg gtgaaaaagc tggagatgaa
    21361 acttggcgtt agcctgctta atcggaccac gcggcaactt agcctgacgg aagaaggcga
    21421 gcgttatttt cgtcgcgtac agtcaatttt gcaggagatg gcagcggcag aatcagaaat
    21481 tatggagacg cgtaatacac cgcgtggact gttacggatc gatgccgcaa ctccagtggt
    21541 gctgcacttt ctgatgccgt tgattaagcc ttttcgtgaa cgctatccgg aagtcacttt
    21601 atcgctagtc tcctccgaaa cgattattaa tttgatcgaa agaaaagtgg atgtcgcgat
    21661 acgcgccggt acgttaacgg attccagctt acgtgccagg ccgctattta acagttatcg
    21721 aaaaattatc gcctcccccg attatatttc ccgctacggg aagccagaaa cgatcgacga
    21781 tttaaagcaa catatttgcc tgggattcac tgaacccgct tccctcaata cctggccgat
    21841 agcctgtagc gatggacaat tacatgaggt taagtacggt ttgtcatcca atagtgggga
    21901 aacactgaaa cagctttgcc tgagtggcaa cgggattgcg tgtttgtccg actacatgat
    21961 cgacaaagaa atcgctcgcg gagaattggt ggagttaata gcagataaag tgttgccagt
    22021 agaaatgcca ttcagtgcag tctattacag cgaccgtgcg gtaagtacgc gcatccgggc
    22081 ttttatcgat ttccttagcg agcatgtaaa aacagctccc ggaggagctg tcagagaggc
    22141 ttaatcccat tcaggagcca gaccttccgg gctaaccagg cggtcgttgc aatccagtgc
    22201 ggcgatcgct tttttatctt cggcatcaag ctgtaaattt tgtgccttaa gattactctc
    22261 caggttttca cgtttagtag aagaaggaat tactgagtaa ccttccccca tagcccacgc
    22321 cagaatcact tgagccggag tcgcattgtg tttagctgca atacgagcaa taacctcatc
    22381 tttcagtgcc ttgccatacg ccagcgtcat ataggaagta atatggatac tgtgctgttt
    22441 agcccaagcg accactttac ggttttgcag ataaggagag agttcaatct ggttagtagc
    22501 gatgttttca gcgccaacag cagcaatcgc tttttccatc aatgggatcg taaagttgga
    22561 aataccgatc tcacgcgtca gcccttgttt tttggcttcc agcagcgcct gcataaactc
    22621 ttcaacagag acttcatcgt ttggtgacgg ccagtggatt agcgtcagat caacataatc
    22681 ggtacgcaat ttttgcaggc tctctttcag actcgggatc aatttgtctt tgctgagatt
    22741 ttcaatccag attttagtgg tgatgtggag ttcatgacgt ggcacgccac tttctgcaat
    22801 cgcctgacct actgcggctt cgttatcata gatttgtgcg gtatcaattg cgcgataatc
    22861 aagttcaagc gccgttttca cagatgaaat aacaacgtcg tctttcagac ggaaagtgcc
    22921 taaaccaaat gcagggatag ccataatatg cctcttttaa tgctattttc gttaactgag
    22981 gtgattatgg gcttcagact gttgcggaaa aatggcgtaa aacgcagagg atttttgcga
    23041 ttttggcaat aatagaaata caaacgaaaa aaaacctcga gcgttaactc gaggcttctt
    23101 agtaagtggc ggaacggacg ggactcgaac ccgcgacccc ctgcgtgaca ggcaggtatt
    23161 ctaaccgact gaactaccgc tccaccgaat tcttttacaa ccaccggttt tatgaccggc
    23221 ttactgctta atttgatacc tggcagttcc ctactctcgc atggggagac cccacactac
    23281 catcggcgct acggcgtttc acttctgagt tcggcatgg
//
LOCUS       DAPOXO010000079        23103 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPOXO010000079 DAPOXO010000000
VERSION     DAPOXO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23103
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.079"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..5046
                     /locus_tag="ROH59_003760"
     CDS             <1..5046
                     /locus_tag="ROH59_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntS/YbdA MFS transporter"
                     /protein_id="HDX4806194.1"
                     /translation="DGDNAISNGGTGTQINGDDATANNSGKTIVDGKDSTGTEIAGNN
                     AVVNQDGTLDVSGGGHGIDITGDSAKVDNKGGMTVTDPDSIGIQIDGDKAIVNNDGDN
                     AISNGGTGTQINGDEATVNNNGNTTVDGKDATGTEIAGNNAVVNQDGTLDVSGGAHGI
                     DITGDGAIANTTGAITVADTDSVGIQVDGNAVTVSNDGDSTITNGGTGTQVNGNDAQV
                     NNTGNTTVDGKNSTGTEITGNNGTVNLDGGLIVTGGAYGVEIAGDSAALNNEGDISVS
                     DEGSIGVLINGEKATVSNTGDVNVSNNATGFDITTNEGNISLAGSMQVGDFSTGMDLN
                     GNNNSVTLAAKDLNVTGQKATGVNVSGDANTINITGNVLVDKDQTADNAADYFYDPSV
                     GINVNGSDNNVTLDGKLTVVADSELTTRGSAGAIIFDGSQENITGLSIAGDGNTFRLN
                     GGIQLVGEANKLTDGSTIASERKGSGKVPLVSVDGKSSVHLNGDSTISGDVLLGNTQI
                     IDLRNGAMLDVGADATINMQVDTYERYAMSADHLIDASSGSQLVNNGDINLRSIGFAA
                     ITGEDSFGSNTGNLTLSQYLDGLFANGGYGYLATKGASVVNTGTITTKVAEQESVINL
                     GASLGFNDLVFYNAANSMTGLSAKTHGYVLNENGGKIEMFGRGNVGMLAIDESTAENA
                     GQITLDALWVDVNDTTTLRDNIGNDARGYSVGMGVGTDAGSGPRKNATAVNQQSGVIT
                     VYNAGIGMAAYGAGNTVINQGTINLEKNGNYDSSLGVNSLIGMAAYNSGTAINDQTGV
                     ININADNGQAFYSTGNGVILNYGTICVNTNCLTGNDYNDTDSYTSILYTGGDVITAQS
                     ETQSLTKKATISDKKDGNVVNSGALSGADIAISSGKLVNTSTGTINNAIIINGGALSN
                     EGSVAKVTQNAGTFNNTGSVNSRMTQTGGTFNNQQGGTVKNGSRLANSAIANNMGIWS
                     LGDTSSGSNASMLEINNNAVFKNSGDFILDNSKNAVHLNQSGTFYNTGKMLLSNSSHS
                     GVLNFWGGNGRFINGGIADVTAKSLAVSASDAGSSNAFFWNQSNGVVNFDKDSGVAVK
                     FIHSNYVAQNDGTMNISGNNAIAMEGDKNARLVNNGTINLGTSGTTDTGMIGMQLDSG
                     TTADAVIENNGAINIYANNSFAFSMLGSVGHLVNNGTVTIADGVTGSGLIKQGDSVNI
                     EGVNGNNGNNSEVHYADYTLPDVPGSSVSVAASTPSSDGSQNKLNGYVVGTSSDGSAG
                     KLKVNNASLKGVSVNTGFTAGTSSTSVTFDNVVQGSNLTDAETITSTSVVWNAQGTTD
                     ASGNVDVTMTKNAYTDVATDSSVNTVAQVLDAGYTNNELYSSLNVGTTAELNSALKQV
                     SGSQATTVFNEARVLSNRFSMLSDAAPEVANGLAFNVVAKGDPRAELGNDTQYDMMAL
                     RKSLTLTEHQNLSLEYGIARLEGNGSDTAGDNGVTGGYSQFFGLKHQMAFDNGMNWNN
                     ALRYDVHQLDSSRSVAYGDINKTADANVKQQYLEFRSEGAKTFELREGLNVTPYAGVK
                     LRHTLEGGYQERNAGDFNLSMNSGSETAVDSIVGLKLDYAGKDGWSANATLEGGPNLS
                     YVKSQRTASVSGAGSQRFNIDDGQNGGGFNSLATMGVKYSSQESALQVDAFHWKEDGI
                     SDKGVMLNFKKTF"
     gene            5266..6132
                     /gene="pdxI"
                     /locus_tag="ROH59_003761"
     CDS             5266..6132
                     /gene="pdxI"
                     /locus_tag="ROH59_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HDX4806195.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHLG
                     LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALARDGIAYVPFFPLGGFTPL
                     QSSTLSDVATSLNATPMQVALAWLLQRSPNILLIPGTSSVGHLRENMASDELVLTDDV
                     LATLDSIAQKAG"
     gene            complement(6172..6777)
                     /gene="azoR"
                     /locus_tag="ROH59_003762"
     CDS             complement(6172..6777)
                     /gene="azoR"
                     /locus_tag="ROH59_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDX4806196.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELITELKAHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTEKGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA"
     gene            6978..10880
                     /gene="hrpA"
                     /locus_tag="ROH59_003763"
     CDS             6978..10880
                     /gene="hrpA"
                     /locus_tag="ROH59_003763"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HDX4806197.1"
                     /translation="MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDHAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQQSAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQAADEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPADYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKTRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELIIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVTPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVK
                     EVRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            11153..11953
                     /locus_tag="ROH59_003764"
     CDS             11153..11953
                     /locus_tag="ROH59_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDX4806198.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLNQAVERVHTAIVVQDPTMQRRTM
                     ATFRRITGDNPDAPRWLSYPGFVPQLGNNAESVIFVNPLQGLWPVERYLSLLTGELPR
                     LRDDSDGYGPRGRDFIVHVDFPAEVIQAWQTLKHDAVLIEAMESRSLR"
     gene            12163..13602
                     /gene="aldA"
                     /locus_tag="ROH59_003765"
     CDS             12163..13602
                     /gene="aldA"
                     /locus_tag="ROH59_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDX4806199.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAE
                     VEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGENVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADIELAVKAIVDS
                     RVINSGQVCNCAERVYVQKSIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVALGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEEAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(13644..14645)
                     /gene="gap"
                     /locus_tag="ROH59_003766"
     CDS             complement(13644..14645)
                     /gene="gap"
                     /locus_tag="ROH59_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDX4806200.1"
                     /translation="MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYL
                     LKHDSNYGPFPWSVDYTEDSLIVDGKSIAVYAEKEAKNIPWKAKGAEIIVECTGFYTS
                     AEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAK
                     ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLV
                     IPELSGKLKGHAQRVPVKTGSVTELVSILGKKVTAEEVNNALKKATNNNESFGYTDEE
                     IVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL"
     gene            14834..15364
                     /gene="cybB"
                     /locus_tag="ROH59_003767"
     CDS             14834..15364
                     /gene="cybB"
                     /locus_tag="ROH59_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HDX4806201.1"
                     /translation="MGNKYSRLQISIHWLVFLLVIVAYCAMEFRGFFPRSDRPLINMI
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            15609..15782
                     /locus_tag="ROH59_003768"
     CDS             15609..15782
                     /locus_tag="ROH59_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806202.1"
                     /translation="MKKLALILVMGTLVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            complement(15854..16003)
                     /gene="hokB"
                     /locus_tag="ROH59_003769"
     CDS             complement(15854..16003)
                     /gene="hokB"
                     /locus_tag="ROH59_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HDX4806203.1"
                     /translation="MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            16266..16709
                     /gene="trg"
                     /locus_tag="ROH59_003770"
                     /pseudo
     CDS             16266..16709
                     /gene="trg"
                     /locus_tag="ROH59_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
     gene            complement(16747..17670)
                     /locus_tag="ROH59_003771"
     CDS             complement(16747..17670)
                     /locus_tag="ROH59_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4806204.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGQSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMNGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
     gene            17887..19230
                     /locus_tag="ROH59_003772"
     CDS             17887..19230
                     /locus_tag="ROH59_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDX4806205.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDAASLARNPFRVFTSLLRLELIENELLRQKAAEILRQRDIFTPRCR
                     QLLQEYEQRGGFNETQAQEFVQEALETFRWHQSATVDEKTYRALHKEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLGWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVVAQPITYEDFLPVS
                     AAGIFQSNLGNETQACNHGDASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            19455..21110
                     /gene="opgD"
                     /locus_tag="ROH59_003773"
                     /gene_synonym="mdoD"
     CDS             19455..21110
                     /gene="opgD"
                     /locus_tag="ROH59_003773"
                     /gene_synonym="mdoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein OpgD"
                     /protein_id="HDX4806206.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKNQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEK
                     WARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            21250..21474
                     /locus_tag="ROH59_003774"
     CDS             21250..21474
                     /locus_tag="ROH59_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HDX4806207.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQVSVKEV"
     gene            21537..22076
                     /gene="rimL"
                     /locus_tag="ROH59_003775"
     CDS             21537..22076
                     /gene="rimL"
                     /locus_tag="ROH59_003775"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HDX4806208.1"
                     /translation="MTETIKVSESLELHAVAESHVTLLYQLICKNKTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     PHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDSQ"
     gene            complement(22068..23048)
                     /locus_tag="ROH59_003776"
     CDS             complement(22068..23048)
                     /locus_tag="ROH59_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LbetaH domain-containing protein"
                     /protein_id="HDX4806209.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKSVLLRQIIAMSDFNDVIAGSAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGTVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAYISDSVTISDSLVCGQCRIFGHALIDQHSMIVAAQGLTPDHQLLLQIYDRAKV
                     SASRIVHQAQIYGDAVVRYAFIEHRAEVFDFASIEGNEENNVWLCDCAKVYGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLIGGNAVVRGGPILLDEHVVIQGESR
                     ITGAVIIENHVELTDHAVVEAFDGDTIHVRGPKVINGEERITRTLLAGLL"
BASE COUNT         5949 a         5481 c         6085 g         5588 t
ORIGIN      
        1 gacggcgaca acgccatcag caacggcggt accggcacac aaatcaacgg tgacgacgcg
       61 accgcgaaca acagcggcaa aaccattgtc gacggcaaag attccaccgg taccgaaatc
      121 gcgggcaaca atgcggtggt gaatcaggac ggcacgctgg atgtcagcgg cggcggtcac
      181 ggtattgata tcaccggcga cagcgccaaa gtggataaca aaggcggtat gacggttacc
      241 gatccggatt ccatcggtat ccagatcgac ggtgataaag ccatcgtcaa caacgatggc
      301 gacaatgcta tcagcaacgg cggcaccggc acgcaaatta acggcgatga agccaccgtg
      361 aataataacg gtaacaccac tgttgatggc aaagacgcca ccggcacgga aatcgcgggt
      421 aacaacgcgg tggtgaatca ggacggcacg ctggatgtca gcggcggtgc tcacgggatt
      481 gatatcactg gagacggcgc cattgcaaac acgacaggag cgatcactgt agcggatacg
      541 gactctgtcg gtattcaggt tgatggtaat gcagtgaccg tcagcaatga cggagacagc
      601 accattacta acggcggtac gggcacgcag gttaacggca acgatgctca ggtcaacaat
      661 actggcaaca ccacggtaga cggcaaaaac tccaccggaa cagaaattac gggcaataac
      721 ggcactgtaa atctggatgg tggtctgatt gtgacgggtg gtgcctatgg cgtggagatc
      781 gctggcgaca gcgccgcgct aaacaatgaa ggagatattt cggtttccga tgagggctca
      841 attggcgtac tcatcaacgg tgaaaaagca accgtatcca acacgggtga tgttaacgtc
      901 agcaataacg cgacaggttt tgacattacc actaatgaag ggaatatttc gctggcaggc
      961 agtatgcagg tgggcgactt ctctaccggg atggatctaa acggtaataa caacagcgtc
     1021 acgctggcgg caaaagatct gaacgtcacc ggtcagaagg cgacaggcgt gaatgtatcc
     1081 ggcgatgcca acactattaa tatcaccggt aatgttctgg tagataaaga tcaaacggct
     1141 gataacgcgg cagattattt ctacgacccg tctgtgggga ttaatgtcaa cggtagtgat
     1201 aacaatgtca ctctggacgg taagttaacg gttgttgctg acagtgaact tactacacgc
     1261 ggttctgctg gcgccattat atttgatggc agccaggaga atatcaccgg actcagcatt
     1321 gcaggtgatg gtaatacttt ccgtctgaat ggcggtattc aactggttgg tgaggcgaac
     1381 aagctaactg acggttccac tattgcatcc gagcggaaag gcagtggaaa ggtacctctt
     1441 gtcagtgttg atggaaaatc gtccgttcat ctgaacgggg attccactat tagcggtgat
     1501 gtgctgctcg gcaatacaca aatcattgat ttgcggaatg gtgccatgct ggacgtcggt
     1561 gcggatgcca cgatcaacat gcaggttgat acttacgagc gttatgctat gtcagccgat
     1621 cacctcattg atgcatcgtc tggctctcag ttggtcaata acggtgatat taatctccga
     1681 agcatcggtt ttgccgctat tactggtgag gattcattcg gaagcaacac tggcaatctc
     1741 acgctttctc agtacctcga tgggctgttt gcaaacggag ggtatggcta tttagccacc
     1801 aaaggggcca gtgtcgtgaa cacaggcact atcactacga aagtggcgga acaagagagc
     1861 gtaatcaacc ttggagcgtc actgggtttt aatgatttag tcttttataa cgcagcgaac
     1921 agtatgacgg gccttagcgc caaaactcat ggttatgtac ttaatgagaa cggcggcaaa
     1981 atcgagatgt tcggacgtgg caatgtcggt atgttggcca tcgatgaaag tacggcagaa
     2041 aacgcggggc agattacact ggatgcactg tgggttgatg taaacgatac aacaactttg
     2101 cgtgacaaca ttggtaacga cgccagagga tattctgttg gtatgggcgt tgggacagat
     2161 gctggcagtg gaccgaggaa gaacgccaca gcagtcaacc aacagagtgg tgttatcacc
     2221 gtttataacg ccggaattgg tatggccgcc tacggcgctg gtaatacggt tattaaccag
     2281 ggcaccatta atctggagaa aaacggtaat tacgatagta gcctgggcgt gaattcgctt
     2341 atcggtatgg ctgcatataa cagtggtacc gccattaacg atcaaaccgg tgttatcaat
     2401 attaatgctg acaatgggca ggcattttat agcactggta acggtgtcat tcttaactat
     2461 ggcaccattt gtgttaacac taattgcctg acgggcaatg actataatga tactgactcc
     2521 tatacctcga tattatacac gggtggcgat gtcatcactg cacagagtga aacacaaagt
     2581 ctgaccaaaa aagccacgat tagcgacaaa aaagacggta atgttgttaa cagtggtgcg
     2641 ctttccggtg ctgatattgc gattagtagc ggtaagttag ttaatacatc aacgggtacg
     2701 attaataacg caataattat caacggcggt gcgttaagta acgaaggctc tgtggcgaag
     2761 gtgacgcaaa acgccggtac tttcaataac acagggtcgg ttaacagtcg tatgactcag
     2821 acaggaggaa cgttcaataa ccaacagggc gggacggtga agaacggctc cagactggcc
     2881 aacagcgcta ttgctaataa catggggatc tggtcccttg gcgatacgag tagtggtagt
     2941 aatgccagca tgctggaaat taataataat gccgtgttca aaaacagtgg tgacttcatt
     3001 ctggataata gcaaaaacgc tgttcatctg aatcagtcag gtacgttcta caataccggg
     3061 aaaatgttgc tatccaactc ttcccatagc ggcgtactaa atttctgggg tgggaatggg
     3121 cgctttatta acggcggtat tgcggatgtc acggcgaaat ctttggccgt aagcgccagt
     3181 gatgccggga gcagcaatgc cttcttctgg aaccagagca atggggtcgt caattttgat
     3241 aaagacagcg gcgttgcagt gaaattcatt cacagcaatt acgttgcgca gaatgacggc
     3301 accatgaata ttagcggtaa taacgctatt gcgatggaag gggataaaaa cgcacgactg
     3361 gttaacaacg gcacgatcaa cctcggaacg tcgggcacga ccgacacggg catgatcggg
     3421 atgcaactgg acagcggcac gacagctgat gcggtcattg agaacaatgg cgccatcaac
     3481 atttacgcca acaactcctt tgcatttagc atgttgggtt ccgtaggcca cctcgtgaac
     3541 aacggcacag tgactattgc cgatggagtg acaggttccg ggctaatcaa gcaaggtgac
     3601 agcgttaaca ttgaaggtgt gaacggcaat aacggtaaca atagcgaagt gcattatgct
     3661 gattacactt tgcctgatgt acctggctcg tcggtttctg ttgcggccag caccccgtcc
     3721 agtgacggaa gccagaacaa actgaatggt tatgttgtag gaaccagttc tgacggcagt
     3781 gccggcaagc tgaaagtgaa caatgcaagc ctgaaagggg tttctgttaa caccggattt
     3841 acggctggaa ccagctccac ctccgtgacc ttcgacaacg tcgttcaggg cagtaatctg
     3901 accgacgcag agacgattac atcgacctct gtggtatgga acgcgcaagg cactactgac
     3961 gccagcggca acgttgatgt cacgatgact aaaaatgcct acaccgatgt agcaacagat
     4021 tcatctgtta acaccgtcgc gcaggtactg gatgcgggct ataccaacaa cgagttgtac
     4081 agcagcctga acgtaggcac cacggcggaa ctgaacagtg cgctgaaaca ggtcagcggc
     4141 agccaggcaa caacggtatt caatgaagca cgagtgttaa gtaaccgctt cagcatgttg
     4201 tccgatgcag caccggaagt cgcaaacggt ctggccttca acgtggtagc gaaaggcgac
     4261 ccgcgtgctg aactgggtaa cgacacacag tacgacatga tggcgctgcg taaatctctg
     4321 acgctgactg aacatcagaa cctgagtctg gaatacggga ttgcgcgtct ggagggtaat
     4381 ggttcagata ccgcaggcga taacggagtg acaggcggtt acagccagtt cttcggtctg
     4441 aaacaccaga tggcctttga caacggtatg aactggaata acgccctgcg ttatgatgtg
     4501 caccagctcg acagcagccg ctcggtagcg tacggcgata tcaataaaac agccgatgct
     4561 aatgtgaaac aacagtacct ggagttccgt agtgaagggg cgaaaacctt tgagctgcgt
     4621 gaagggctga acgtcacgcc atatgccggg gttaaactgc gtcacacact ggagggtggc
     4681 tatcaggaac gcaatgcggg tgactttaac ctgagcatga acagcggtag cgaaacggca
     4741 gtggacagca ttgttgggct gaaactggac tatgccggta aggacggctg gagtgcgaac
     4801 gccacgctgg aaggcggccc gaacctgagc tatgtgaaaa gccagcgaac tgcgagcgtt
     4861 tcgggcgcgg gaagccagcg tttcaacatt gatgatggtc agaatggtgg tggtttcaac
     4921 agcctggcga caatgggtgt gaaatacagc agccaggaaa gtgcgttgca ggtagatgca
     4981 ttccactgga aagaagacgg catcagtgat aaaggtgtga tgctaaactt caagaaaacg
     5041 ttctaatttt tagcatgtaa tgcataaacc gcaacgctga tacaggttgc ggttttttta
     5101 ttgccggatg cggtgcttga cgtgtcttaa cctgcctggg gtttcgtgtc tttcagggca
     5161 acagtacaac tcatcccgca atcttgttta caccctcgca ttatttatct cttttcgttt
     5221 ctatactgat ttttcttaat ccgttttatt acagggcagg gtgcgatgag cagcaacaca
     5281 tttactctcg gtacaaaatc cgttaaccgt cttggttatg gcgcgatgca actggctggt
     5341 cctggggttt ttggcccccc aagagatcgc cacgtcgcta taaccgtgct gcgcgaggcg
     5401 ctggcattgg gcgtcaatca tattgatacc agcgactttt atggtccgca cgtcaccaat
     5461 cagattatcc gcgaagcgct ttatccttac tctgacgacc tgacaattgt cactaaaatt
     5521 ggtgcgcggc gtggagagga cgcatcctgg ttacccgcat tttctccggc agagctgcaa
     5581 aaagcggtac acgataatct acgtaatctc ggcctggacg tactggatgt ggttaacctg
     5641 cgcgttatga tgggggatgg tcatggccca gcggaaggat cgattgaggc cagcctgaca
     5701 gtgctggcgg agatgcaaca acaaggtctg gtaaaacatc ttggcctgag taacgtcaca
     5761 ccgacgcagg ttgcagaggc gcgaaagatt gccgaaatcg tctgcgtgca gaacgaatac
     5821 aacattgccc accgtgctga tgacgcaatg attgatgctt tggctcgtga tggcattgcc
     5881 tacgtgccgt tcttcccgct cgggggcttt acgccgctgc aatcctccac gctttccgat
     5941 gttgctacaa gccttaatgc gacaccaatg caggtggcgc tggcgtggct gttacagcgt
     6001 tcaccgaata ttttgctgat tcctggcacc tcttcggtgg ggcatctgcg ggagaatatg
     6061 gcgtccgatg aattagtgct aacggatgac gtgctggcaa cgctggacag tattgcgcaa
     6121 aaggcgggtt aaataaaaaa cctcccactt tcgtgggagg catcataaat cttatgcagc
     6181 aacaatactg tcgatggctg cttttgcgtc agactgtgct ttcgctgcca tttccgggcc
     6241 gtacgcgatc ccttcggcga agacaaattt cacatcggta atgccgataa agcccaggaa
     6301 tgtggacaga tatggcgtta ccagatccgt tgggccatct ttatggatcc caccgcggct
     6361 ggtgataacg atggcttttt taccggtgac caggccttcc ggacccttct cggtatagcg
     6421 gaaagtaacg cctgcacgtg caaccaggtc aaaatagttt ttcaactggg tcgagatatt
     6481 gaagttatac atcggtgccg caataacgat aacgtcgtgg gctttcagct cggtaatcag
     6541 ctcatcggaa agcgccagag cttcctgctg acgcggagtc agcggcgcat cgctcggacg
     6601 cagtgcacca accagttcac catccaggac cggaatcgga tttgcagcca ggtcacgcac
     6661 ggtgatttca tcagcggagt gcttttcgcg ccattgttca acaaaataat cggacaactg
     6721 attagactga gagtaccctg ccaggatgct ggatttaaga actaatacct tgctcatggt
     6781 gtttccttat agatatttga atgggcaatg ccccgttgct tgttgacact ttattcacaa
     6841 tcctgccaca gagatagcgc aataaatcga agcctatgtt cgaatttatt gaacaacgca
     6901 tagaaagctg cgatgtggta ctctatatct atcatttaaa agaaaattaa tcaggcagcc
     6961 tactgcccac taacgttatg acagaacaac aaaaattgac ctttactgcc ttgcagcagc
     7021 ggctggattc gttgatgctg cgtgacagat tgcgtttttc tcgccgtctg cacggtgtga
     7081 agaaggttaa aaatcctgat gcacaacagg ccattttcca ggagatggcg aaagagattg
     7141 accatgcggc agggaaagtc ctgctgcgtg aagcggcacg accggagatt acttacccgg
     7201 acaatttgcc ggttagtcag aaaaagcagg acattctcga agcgattcgt gaccaccagg
     7261 tggtgatcgt cgccggggaa acgggttccg gtaaaacgac tcagctaccg aaaatctgta
     7321 tggagctggg gcgcgggatt aaagggctga tcggccatac ccagccgcgt cggctggcgg
     7381 cgcgaacggt ggcgaaccgt attgcggaag agctaaaaac ggagccgggc ggttgcatcg
     7441 gttacaaagt gcgtttcagc gatcacgtca gtgataacac gatggtcaag ctgatgaccg
     7501 acggtatcct gctggcggag atccagcaag accgcctgct gatgcagtac gacaccatca
     7561 ttattgacga agcgcacgaa cgcagcctga atatcgattt tctgctcggc tatttgaaag
     7621 agttgctgcc gcggcgtcct gacctaaaaa tcattatcac ttccgcgact atcgacccgg
     7681 aacgcttttc gcgccacttt aataatgcgc cgattatcga agtctccggt cggacctatc
     7741 cggtggaagt gcgctatcgc ccgattgttg aagaagccga tgataccgag cgcgatcagt
     7801 tgcaggcgat ttttgacgcc gtagacgaac tgagccagga aagccctggc gacattctga
     7861 tctttatgag cggcgagcga gaaattcgcg ataccgccga tgcgctgaac aagctgaact
     7921 tacgccatac cgaaatcttg ccgctttatg cacggctttc caacagcgaa cagaaccgcg
     7981 tgttccagtc gcacagcggg cgacgcattg tactggcgac caacgtcgcg gaaacctcgc
     8041 tgaccgtacc gggtattaaa tacgttatcg acccaggtac agcgcgtatc agccgctaca
     8101 gctatcgcac caaagtgcag cgtttgccga ttgagccaat ttcgcaggct tcagctaatc
     8161 agcgtaaagg ccgctgtggt cgtgtgtccg aagggatctg tattcgtctc tattccgaag
     8221 acgatttcct ttcgcgcccg gagtttaccg atccggagat tctgcgtacc aacctggcct
     8281 cggttatttt gcagatgacc gcactgggct tgggcgatat cgccgcattc ccgtttgtcg
     8341 aagcaccgga taaacgcaat atccaggatg gcgtgcgtct gctcgaagaa ctgggcgcga
     8401 tcaccactga tgaacagcaa agtgcttata aactgacgcc gctcggtcgt cagctctcgc
     8461 agttgcctgt cgacccacgt ctggcgcgta tggtgctgga agcgcaaaaa catggctgcg
     8521 tgcgtgaggc gatgattatc acgtccgcgc tctccattca ggatccgcgc gagcgtccga
     8581 tggataaaca gcaggcagct gacgaaaaac atcgtcgctt ccacgacaaa gagtctgact
     8641 tcctggcatt tgtgaatctg tggaattatc ttggcgagca gcaaaaggcg ctttcttcaa
     8701 acgccttccg tcgcctgtgt cgtaccgatt atctcaacta tctgcgcgtg cgcgaatggc
     8761 aggatatcta cacccagttg cgccaggtgg tgaaagaact tggcattccg gttaacagcg
     8821 aaccggcgga ttatcgcgaa attcacattg cgttgctgac cggtttgctt tcgcatatcg
     8881 gcatgaaaga tgccgataaa caagaatata ccggcgcacg taacgcgcgt ttctccatct
     8941 tccccggttc tggtttattc aaaaagccgc cgaaatgggt aatggtggcg gaactggtag
     9001 aaaccagccg cctgtggggg cgcattgctg cgcggatcga cccggaatgg gtggagccag
     9061 ttgctcagca tttgattaaa cgcacctaca gcgaaccgca ctgggaacgg gcgcagggcg
     9121 cggtgatggc aacggaaaaa gtcactgttt atggtttgcc gattgttgcc gcgcgcaagg
     9181 tcaactacag ccagatcgat ccggcgttat gtcgtgaact ctttattcgc cacgcgctgg
     9241 tggaaggtga ctggcagacg cgtcacgcat tcttccgcga aaacctgaaa ctacgggcgg
     9301 aagtagaaga gctggaacac aaaactcgtc gccgcgatat tctggtggat gacgaaacgt
     9361 tgtttgagtt ctacgaccag cgcatcagtc acgatgtgat ctctgcacgc catttcgaca
     9421 gttggtggaa aaaagtcagc cgcgaaacgc ctgatttgct caactttgaa aagagcatgt
     9481 tgatcaaaga aggggcggaa aaaatcagca agctggatta cccgaacttc tggcatcagg
     9541 gcaatctcaa gctgcgtttg agttatcagt ttgagccggg ggcagatgct gacggcgtga
     9601 ccgtacatat tccgctgccg ctgcttaacc aggttgagga gagcgggttt gagtggcaga
     9661 tccccggcct gcgccgtgag ctgatcatcg ccctgattaa atcgttgccg aagccggtac
     9721 gccgtaattt tgtacctgcg ccaaactatg ccgaagcgtt tttaggccgc gtcacaccgc
     9781 tggaattgcc gttgctcgac agccttgaac gagagcttcg gcggatgact ggcgtcaccg
     9841 ttgaccgcga agactggcac tgggatcagg tgcccgatca cctgaaaatc accttccgcg
     9901 tggtggatga caaaaacaag aagctaaaag aagggcgctc attacaggat ctgaaagacg
     9961 ccctgaaagg caaagtgcag gaaacgctgt ctgccgtggc ggatgacggt atcgagcaga
    10021 gcggtttaca tatctggagt tttggtcaac tgccggaaag ctacgagcag aagcgcggca
    10081 actacaaagt gaaggcttgg ccggcgctgg tggatgagcg tgacagcgta gcgatcaaac
    10141 tgtttgataa cccgctggaa cagaagcagg caatgtggaa cggtcttcgc cgtttactgc
    10201 tgctaaatat tccatcgccg atcaagtact tgcacgaaaa gctgccaaac aaagccaagc
    10261 tggggctgta ctttaacccg tatggcaaag tgctggagct gatcgatgac tgtatctcct
    10321 gcggtgtgga tcaactgatc gacgccaatg gtggcccggt ctggacggaa gaaggctttg
    10381 ctgcgctgca tgaaaaagtc cgtgctgaac tgaacgacac ggtggtggat attgcgaagc
    10441 aggtcgagca aatcctcact gcggtgttca atatcaacaa acgtctgaaa gggcgggtgg
    10501 atatgaccat ggcgctgggg ctttctgaca ttaaagcgca gatgggcggg ctggtgtatc
    10561 gcggttttgt cactggtaac ggcttcaaac gactgggcga cacgctgcga tatttgcagg
    10621 caattgaaaa acgactggaa aaactggcgg tcgatccaca tcgcgaccgt gctcagatgc
    10681 tgaaagtcga aaacgtccag caggcgtggc agcaatggat caacaaacta ccgcctgcac
    10741 gtcgtgagga tgaagacgtg aaagaggtcc gctggatgat agaagagctg cgcgttagtt
    10801 acttcgctca acaacttggc acgccttatc cgatttcgga taagcgtatt ttgcaggcga
    10861 tggagcagat tagcggttaa cactgctatt tgcctgataa atctaaaacc cggtaagcat
    10921 ttagcgccgg gttttttatt aattctaaaa acgataaggg aaaaaattca ggagttcaga
    10981 aaaatacaat tctctgctgc aagatgaata atgtttatct acagcatttc cttaaaagat
    11041 atgtcaggct tgcggagtgg cagttcagga aatacgactt cctcctttca gagtgctccg
    11101 cttctcacta ttatctcacg cagtattctt aagggaacga taaggaggaa ccatgaatat
    11161 taccccgttt ccgacgcttt cgccggcaac catagatgcc ataaatgtta tcggacagtg
    11221 gctggcgcag gatgatttct ccggtgaggt gccgtatcag gccgattgcg tgatccttgc
    11281 aggcaatgcg gttatgccga ctatcgatgc ggcatgtaag attgcccgcg atcagcaaat
    11341 tcctttactg attagtggtg gtatcggtca ctcgacaact tttttgtata gcgccatcgc
    11401 acagcatccg cactacaaca ctatccgcac cactggcaga gcagaagcta ccattctggc
    11461 ggatatcgct catcagttct ggcatattcc gcatgaaaaa atctggattg aagaccagtc
    11521 aacaaactgc ggtgaaaacg cacgctttag catcgcgtta ttgaatcagg ctgtagaacg
    11581 agttcatacg gctatcgttg ttcaggaccc caccatgcag cggcgcacga tggcgacgtt
    11641 ccgccgtata accggggata atcccgatgc accacgctgg ttaagttatc ccggattcgt
    11701 tcctcagtta ggaaataacg cagagagtgt aatctttgtt aatccgttgc aaggattatg
    11761 gccggttgag cgttatctat cgctactcac tggcgagctg ccgcgtttac gcgatgatag
    11821 cgatggctac ggcccccgcg ggcgagattt tatcgttcac gttgattttc cggcagaagt
    11881 cattcaggca tggcaaacgc tgaaacatga tgcggtgctc atcgaggcga tggaaagtcg
    11941 ctcgttacgt taaaaattgc ccgtttgtga accacttgtt tgcaaacggg catgatttct
    12001 gacttttatt tctgcctttt atttctgcct ttaattcctt ttacacttgt ttttatgaag
    12061 cccttcacag aattgtcctt tcacgatgcc gtctctctga tgattgatgt taattaacaa
    12121 taaatttacc aaaaacaaac atgcaaatca caggagtcgc ccatgtcagt acccgttcaa
    12181 catcctatgt atatcgatgg acagtttgtt acctggcgtg gagacgcatg gattgatgtg
    12241 gttaaccctg ctacagaggc tgtcatttcc cgcattcccg atggtcaggc cgaggatgcc
    12301 cgtaaggcaa tcgatgcagc agaacgtgca caaccagaat gggaagcgtt gcctgctatt
    12361 gaacgcgcca gttggttgcg caaaatctcc gccgggatcc gggaacgtgc cagtgaaatc
    12421 agtgcgctga ttgtcgaaga agggggcaag atccagcagt tggctgaagt cgaagtggct
    12481 tttactgcgg actatatcga ttatatggcg gagtgggcac ggcgttacga gggcgagatt
    12541 attcaaagcg atcgtccagg agaaaatatc cttctgttta aacgtgcgct tggcgtgact
    12601 accggcattc tgccgtggaa ctttccgttc ttcctcattg cccgcaaaat ggctcccgct
    12661 cttttgaccg gtaataccat cgtcattaaa cccagtgaat ttacgccaaa caatgcgatt
    12721 gcattcgcca aaatcgttga tgaaataggc cttccgcgcg gcgtgtttaa ccttgtactc
    12781 gggcgtggtg aaaacgttgg gcaagaactg gcgggtaacc caaaggttgc aatggtcagt
    12841 atgacaggca gcgtctctgc aggtgaaaag attatggcga ctgcggcgaa aaacatcacc
    12901 aaagtgtgcc tggaattggg gggtaaagca ccggctatcg taatggacga tgccgatatt
    12961 gaactggcag tcaaagccat cgttgattca cgcgtcatta atagtgggca agtgtgtaac
    13021 tgtgcagaac gtgtttatgt acagaaaagc atttatgatc agttcgtcaa tcggctgggt
    13081 gaagcgatgc aggcggttca atttggtaac cctgctgaac gcaacgacat tgcgatggga
    13141 ccgttgatta acgccgcggc gctggaaagg gttgagcaaa aagtggcgcg cgcagtagaa
    13201 gaaggggcga gagtggcgtt gggtggcaaa gcggtagagg ggaaaggata ttattatccg
    13261 ccgacattgc tgctggatgt tcgccaggaa atgtcgatta tgcatgagga aacctttggt
    13321 ccggttctgc cggtggtcgc atttgacacg ctggaagagg ctatctcaat ggctaatgac
    13381 agtgattacg gcctgacctc atcaatctat acccaaaatc tgaacgtcgc gatgaaagcc
    13441 attaaagggc tgaagtttgg tgaaacttac atcaaccgtg aaaacttcga agctatgcaa
    13501 ggcttccacg ctggatggcg taaatccggt attggcggcg cagatggtaa acatggcttg
    13561 catgaatatc tgcagaccca ggtggtttat ttacagtcgt agtgagtgaa agaggcggag
    13621 gttttttcct ccgcctgtgc gcgtcagagt ttagcgaatt tttcgagggt gcgaataagc
    13681 tgcgtgacga agccatattc gttatcgtac caggcgaccg ttttcaccag ttgtaaatcg
    13741 cccacggcgg taatttccgt ttgcgtggca tcaaacaccg aaccgaaatg gctgccaatg
    13801 atatcggaag agactatttc ttcatcggta taaccaaatg actcgttatt gtttgtcgcc
    13861 tttttaagcg cgttgttcac ctcttcggca gtcacttttt ttccgagaat cgacaccagt
    13921 tcagtgaccg aacctgtttt caccggcacg cgttgcgcat gacctttcag tttgccgctc
    13981 agttccggga tcaccaggcc aatggctttt gccgcccccg tagtgtgggg aatgatattt
    14041 tctgccgctg cgcgtgaagc acgtaaatct ttaccacgcg ggccatccac cagtgactgg
    14101 gtgccggtat aggcatgaat ggtcgtcatc gtgccgactt ctatcccgaa actgtcatgc
    14161 aaggctttgg ccatcggcgc aaggcagtta gtggtgcatg acgccacgga aacaatggtg
    14221 tcgttgccat ccagagtgtc gtcattgacg ttataaacga tggttttcat ttcaccggca
    14281 ggggcggaaa tcaacacctt cttcgcgcca gcatcaagat gcgcctgcga tttctcggcg
    14341 gaggtataaa agcctgtaca ttcgacaatg atttctgcgc ctttcgcttt ccacggaata
    14401 tttttagcct ctttttcggc gtaaaccgcg atacttttcc catcaacgat aagtgaatct
    14461 tccgtataat caacgctcca ggggaacggt ccgtagtttg aatcatgttt cagcaggtag
    14521 gcgagaattt ttggggaagt gagatcatta atagcgacaa cgtctatgtt gcttttgact
    14581 tcaagtaatc gacgcaacac cagtcgaccg atacgaccaa aaccattaat accaacttta
    14641 ctcatggtct tctcctgtca ggaacgttcg gatgaaaatt gatcctttcc aggcttagac
    14701 caggatggcg ggatgggcaa tctacattct tgcagtgaaa cgtaacgtac tgaaaacggg
    14761 tgaacaatat ttaatgaaat tttaagaaaa gcccgttatg ttaacggcaa attatgttaa
    14821 agcaggaaat gttatgggaa ataaatactc aaggttacaa atcagcattc actggctggt
    14881 ctttttgctg gttatcgtag cgtattgcgc aatggagttt cgtggtttct tcccacgtag
    14941 cgatcggccc ctcatcaaca tgattcatgt ttcctgtggc atctcaattc tcgtactgat
    15001 ggtggttcgt cttttgttaa ggctgaaata cccaaccccg ccgattatac ctaagccaaa
    15061 accgatgatg acgggactgg cgcatttggg ccatttggtg atttatctcc tgtttattgc
    15121 gctgccggtg attggtttgg tgatgatgta taaccggggc aacccgtggt ttgcgtttgg
    15181 tttgacgatg ccttacgctt cagaggccaa tttcgagcgg gttgatagct taaagtcgtg
    15241 gcatgaaacg ctggcgaatc tgggatattt tgtcatcggg ttgcacgctg cggctgcact
    15301 ggcacaccac tatttctgga aggacaacac acttctacgc atgatgccac gtaaacgttc
    15361 ctgaaggata tttaaagaaa acgcctgtac taaaaccgac ccgtggtaca ggcgaagaat
    15421 acgggcctac atcggaagcg cctattatat ttatttgtat gacaaataaa accataatcc
    15481 ttgtctatac gtccatctgg cttatcttta atcaattcac ccgatctttg atctcatcaa
    15541 cggtatcaaa ataaaccagc gtataacgtt caaatcgaac ataagattcg ataaatcatg
    15601 gaggttatat gaaaaaactg gcacttatcc tggttatggg aacgcttgtt tccttttatg
    15661 ccgatgccgg gcgcaaaccc tgttctggtt cgaaaggggg gatctcacac tgtacggcag
    15721 gcggcaaatt tgtctgtaat gatggttcta ttagtgcatc gaaaaaaaca tgcactaact
    15781 gaagtgtaaa aggggggcca tgagaaaatg aatccgctag tcagatgcgc ggggaaaacc
    15841 cccgcgcttg cccttacctg gacgtgcagg ccatgagcgc agcaacctcc ttatcaccgt
    15901 cccggaaccg cagttcgtag agcgtttgtc gggtcaggag tgtgaatgtc agaatcgtaa
    15961 tgcagataat gagcagacac accaccagag ggttgtgctt catagccttt ctccttgccg
    16021 gatggcgggt aagaggctaa gatctgaatt gctaggttca ttcgttggcc tcggttgata
    16081 gaaatatcgg tcggggcctt cgtctttctg attccaggtt agcctgaaaa cagaaagtct
    16141 caggcacccg tgagcatcct atgtggtttc cttagggacg aaaataatca cctgacgaaa
    16201 tcgcgtgctg ctttccagaa tttttcgtca ttcggtttag ccagtttaat cattcgttac
    16261 tctcgcaagg ccgtggattt gccgttgtcg ccagcgaagt acggacactc gcaagccgca
    16321 gcgcccaggc ggcgaaagag attgaaggct tgatcagtga atcagtcagg ttaattgacc
    16381 tgggatcgga tgaggtggca acggcaggga aaaccatgtg cactattgtt gatgccgtcg
    16441 cgagtgtcac acatatcatg caggaaatcg ccaccgcctc gggtgaacaa agtcgaggca
    16501 taacgcaggt tagccaggcg atttctgaaa tggataaggt gacgcaacag aatgcttctc
    16561 tggtagaaga ggcctcaacg gcggcggtgt cccttgaaga acaggcggca cgactaactg
    16621 aggcggtgga cgtattccgt ctgaacaaac attctgtgtc ggcagaacca cgaggagcgg
    16681 gtgaaccagt tagttttgct acggtgtgaa aatgttaaag gagggatcga cagatccctt
    16741 cacctttcag aacggcattg attttcgaat agcgttaatc atcaactggc aaccagaaga
    16801 gaacgtcgca tctacgcggg tcagtattcc aatcggttcg cctgcaccat gtcccggaac
    16861 aggcagggct accagcgtgg catgacgcag gtcgtctttt acagcgccag aagggacaaa
    16921 ccacacgtaa tcgtattcaa ccgtaagttg acgagatagc gaagcagaca gcgtttcgat
    16981 acaacccgaa ggaattttac atccctggct ctgcactaat gcatctgaat gctggcgtgg
    17041 cgcagtgcct tctggtgata caacgaccgg ccattccagc acccggctta gcgttacgtt
    17101 ctcctgaagt agcgggtgat tagggcggac aaccagcttc agcgattcaa gaaacagtag
    17161 ttcgtaatta agcccgttca tcagttcagg atctgacatc cgaccaatgc cgatatcgat
    17221 ttccccggtt tttaaacccg ccagaatcat agggttactc attgtcgcaa cttgcaaggt
    17281 cgtctctttt tgttgctgat gaaactgacc tataaccgaa ggtaatatcc ctagtgccgc
    17341 agtaggtagc gcaccaaccc tgacgacatc attattaaga ccttctttac gatgaagcga
    17401 ctgtccggca gtgttgatgg cgtcaagaac tctgactgca tgcgttaaaa attgttcgcc
    17461 gggtaaggta agttgcgccc cctgacgacc acgctcaaac aagcgagcgc ccgtcagctg
    17521 ctccagttca ttcaatgtct tagagagcgc aggttgactc aaattaaggg tttcagccgc
    17581 gcgccccaaa gttccttgtt gtgcgacagc tacgaatgta tgaaggtggc gcaaacggat
    17641 gcgctgacta aacagactat ttttttccat aagcgatgtt aaaaacgaag cggtgtcgct
    17701 gacaagtgaa gttgttttat tatgataact tgattgcaaa atattattaa caattaaagc
    17761 aactatgtta cagcaaaatg gataatattg atgttttcgc ggcgagatca cagtttgtaa
    17821 attcttccag ccggagtgaa tgcggttacc tacactccag attactgacc actggaggca
    17881 gacactatgg cgaacagcat cacggcggat gagattcggg aacagttttc gcaggcaatg
    17941 tcagccatgt accagcaaga agttccgcag tacggcacgc tgctggaact ggtagctgat
    18001 gtaaatctgg cggtgctgga aaacaatcct caactgcacg aaaaaatggt aaatgcagac
    18061 gaactggcgc gactgaatgt tgaacgtcat ggggcgattc gcgttgggac tgcacaagag
    18121 cttgctactc ttcggcggat gtttgccatt atggggatgt acccggtgag ctattacgat
    18181 ctctcgcagg caggggtgcc ggtacattcg acagcatttc ggcccattga tgctgcttct
    18241 ctggcgcgta atcccttccg cgtttttacc tcattactcc gccttgagct tatcgagaac
    18301 gaattattac gccagaaagc ggcggagatt ctgcgtcagc gcgatatctt caccccacgt
    18361 tgtcgacaac tgttacagga atatgagcag cggggcggtt ttaacgaaac acaggcacag
    18421 gagtttgtgc aggaagccct ggaaacgttt cgctggcacc agtcagcaac ggtagatgaa
    18481 aaaacctatc gcgccttgca caaagaacat cggttgattg ctgatgtggt ctgttttcct
    18541 ggatgccata tcaaccacct gacgccacgc acgctggata ttgaccgggt gcagtcgatg
    18601 atgcctgaat gcggaattga acccaaaatt ctgatcgaag ggccgccgcg ccgcgaggtg
    18661 ccgattttac tacgccagac cagctttaaa gcactggaag agacggtgtt gtttgcgggg
    18721 cagaaacagg gcacacatac cgcgcgcttt ggtgaaattg agcagcgtgg tgtggcatta
    18781 acgccgaaag ggcgacaact gtatgatgat cttctgcgga acgctggaac cgggcaggat
    18841 aatctcactc accaaatgca tttacaggaa accttccgca cttttcctga cagtgagttt
    18901 ttaatgcgtc agcaagggct gggatggttc cggtaccgtc tgacgccttc gggtgaggcg
    18961 catcgtcagg cgattcatcc cggagacgat ccacagccct taatagaacg tggttgggta
    19021 gtggcgcaac ccattaccta tgaagatttc ttgcccgtta gcgcggcggg gatcttccag
    19081 tcaaatctgg gtaatgaaac gcaggcatgc aatcacggtg atgccagtcg cgaagcattt
    19141 gagcaggcgt tggggtgtcc ggttttggat gagttccagc tttatcagga agcggaagaa
    19201 cgcagtaaac gtcgctgtgg tttgctttaa attctgacca tccgcctttg caaaaatttg
    19261 cctgatttta caaacgaatc aggctcatcc catcgacata aaaaaaatgc caatttatgc
    19321 atattctctg atttcaacaa ttggattatt aataaatatt gtctagagtg agcggtcata
    19381 aataagcact ttcttgccgc tgaaaatgac cagcgcggga ccattcacaa caccagaagg
    19441 actcactttc aggtatggat cgtagacgat ttattaaagg ttcaatggct atggccgccg
    19501 tgtgcggtac cagcggcatt gcttctcttt tttctcaggc ggcattcgcg gccgattctg
    19561 atattgccga cgggcaaacc cagcgttttg acttctccat tctacagtca atggcgcacg
    19621 acttagcgca aacagcatgg cgtggtgcac cacgtccgtt acctgatact ctggcgacaa
    19681 tgacgccgca ggcttataac agtattcaat acgacgccga aaaatcgctc tggcataacg
    19741 ttgagaaccg tcaactggac gctcagtttt tccatatggg aatgggattc cgtcgccgcg
    19801 ttcgtatgtt ttctgtagat ccagcaacac atctggcgcg tgaaattcac tttcgcccgg
    19861 agttgttcaa atacaacgat gcgggtgtgg ataccaaaca attagaaggg caaagcgatc
    19921 tcggttttgc cggttttcgc gtgtttaaag cccccgaact ggcgcgccgt gatgtagtat
    19981 cattcctcgg cgcgagttat ttccgcgccg ttgatgacac atatcaatac ggtttgtcgg
    20041 cccgcggcct ggcgatcgac acttacaccg acagcaaaga agagttcccc gactttaccg
    20101 ccttctggtt tgatacggta aaaccagggg caaccacctt taccgtttat gcgttgctcg
    20161 atagcgccag cattactggt gcctataagt tcactatcca ttgtgagaaa aatcaggtga
    20221 ttatggatgt ggaaaatcac ctgtatgcgc gcaaagacat taaacagctg ggcattgcac
    20281 cgatgaccag tatgttcagc tgcggtacta atgaacgtcg gatgtgcgac accattcatc
    20341 cgcaaatcca tgactctgat cgtctgtcca tgtggcgggg caacggcgag tggatttgcc
    20401 gtccgctgaa caatccgcaa aaattgcagt tcaatgctta caccgacaac aacccgaaag
    20461 ggtttggttt attgcaactg gatcgtgatt tctcccatta tcaggacatt atgggctggt
    20521 ataacaaacg cccaagtctg tgggtggaac cgcgtaacaa gtggggtaag ggcaccatcg
    20581 gcctgatgga aatcccaact acgggggaaa cgctggataa cattgtttgc ttctggcagc
    20641 cagaaaaagc tgtaaaagcg ggtgatgagt ttgcattcca gtatcgtctg tactggagtg
    20701 cgcaaccgcc tgttcattgc ccattagcgc gcgttatggc gacgcgtacc ggcatgggcg
    20761 gtttcccgga aggttgggcg ccaggtgaac actatcccga aaaatgggcg cgacgttttg
    20821 ccgtcgattt cgttggtggc gatctgaaag ctgccgcgcc aaaaggcatt gagccggtga
    20881 ttacgctttc cagtggggaa gcgaagcaaa tcgaaattct ctatattgaa cccattgatg
    20941 gttatcgtat tcagtttgac tggtatccga cttcggactc cactgatccg gtcgatatgc
    21001 ggatgtatct gcgttgtcag ggcgacgcta tcagtgaaac atggttatat cagtatttcc
    21061 cgccagcgcc ggataaacgt cagtatgttg atgaccgcgt gatgagttaa tcgttttttc
    21121 ttcggcatct tcttcgggag gtgccgtctg gttaaacacg atcccgctcg cattttttcc
    21181 taagttaaat gagtaatctg ctggtgtgta tttcagatac accttgtcag ccactaacag
    21241 ggagtgcgta tgtttccaga ataccgagat ttaatatccc gtctgaaaaa cgaaaatcct
    21301 cgctttatgt ccttgttcga taaacacaat aaacttgatc atgaaattgc cagaaaggaa
    21361 ggttccgacg gtcgagggta caatgcggaa gtggtccgca tgaaaaaaca aaagctacag
    21421 ttaaaagatg agatgctcaa aatcctgcag caggtgagcg tcaaagaggt gtaaactttc
    21481 ctaagccgcc agccaggcgg cttttttaac agctgcatgg attgactgga gataagatga
    21541 ctgaaacgat aaaagtaagc gaatcacttg aattacatgc tgttgcggaa agtcatgtca
    21601 cacttcttta tcagttaatc tgtaaaaata aaacctggtt acagcagtcg ctaaactggc
    21661 cgcagtttgt tcaaagtgaa gaggacacgc gaaaaacggt gcagggtaat gtgatgttgc
    21721 atcaacgcgg ctatgccaaa atgttcatga ttttcaaaga agatgaactt atcggcgtta
    21781 tctcttttaa tcgtattgaa ccactgaata aaaccgctga aatcggctac tggctggacg
    21841 aacctcatca ggggcagggg atcatttctc aggcgctgca ggcattgatt catcattacg
    21901 ctcagtctgg tgaacttaga cgcttcgtga tcaaatgtcg ggtggacaat ccgcaaagca
    21961 accaggtagc gttgcgcaat ggttttatcc ttgaaggttg cctgaaacag gctgagtttc
    22021 tgaatgatgc ctatgatgat gtgaacttat acgcgcgtat tatcgattca caataaccct
    22081 gccagcagcg ttcgcgtaat gcgctcctcg ccgttaatga cttttggacc acggacatga
    22141 atcgtgtcgc catcaaaggc ttcaacgacg gcgtggtcag ttaactccac atggttttca
    22201 attatcaccg cacctgtaat acggctctca ccttgtatta caacgtgctc gtcgagcaga
    22261 atcggtccgc cacgtaccac ggcatttccg ccaatcaaga catgatgttt taacacacaa
    22321 ttaccttcca caatggcata ttccgccacc tgtgaactgt aatgaatcgt cggaatggca
    22381 tcttcttcta tgccagcttt cacctgcgcg tgaccgtaaa ctttagcgca atcgcatagc
    22441 cagacgttgt tctcttcatt accttcaata ctggcaaaat caaaaacttc ggcgcgatgt
    22501 tcaataaaag cataccggac gacggcatcg ccataaattt gtgcctggtg gacaatacgc
    22561 gaggcgctaa cctttgcgcg atcataaatt tgtagcagga gttgatggtc gggcgttaag
    22621 ccttgtgcgg cgacgatcat agaatgttga tcaattaagg cgtgaccaaa tattctacat
    22681 tgaccgcaaa ctaatgagtc actaatggtg acactgtcac ttatatatgc accctggctg
    22741 atttcactat tatcgatcca gacattatcc gttgcgtaaa cctctcccca cagcacgctg
    22801 gtgccggtga tacgcgtatt cccggaaatc accgttccgc cgaacgcaat agcattctgg
    22861 tcgtaaatcc agcaatttcc ttcctgtgct aacaccgttt cgcgatcgat ccagccgcca
    22921 gcgcttcctg ctatcacatc gttaaaatcg ctcatggcga taatttgccg taataacaca
    22981 ctttttttag tgccatcttc ctgataacta aaggctcgct gttcttcact tagacgatat
    23041 ttacgcatag cgttttccca caggtgactt actataaccg tagcaaattc tgcggctctg
    23101 gct
//
LOCUS       DAPOXO010000080        22571 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.080, whole genome shotgun sequence.
ACCESSION   DAPOXO010000080 DAPOXO010000000
VERSION     DAPOXO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22571
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.080"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            579..769
                     /locus_tag="ROH59_003777"
                     /pseudo
     CDS             579..769
                     /locus_tag="ROH59_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(839..979)
                     /gene="ykgO"
                     /locus_tag="ROH59_003778"
     CDS             complement(839..979)
                     /gene="ykgO"
                     /locus_tag="ROH59_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HDX4806210.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(979..1242)
                     /locus_tag="ROH59_003779"
     CDS             complement(979..1242)
                     /locus_tag="ROH59_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDX4806211.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     gene            complement(1607..1708)
                     /locus_tag="ROH59_003780"
     CDS             complement(1607..1708)
                     /locus_tag="ROH59_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806212.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
     gene            complement(2181..3323)
                     /locus_tag="ROH59_003781"
     CDS             complement(2181..3323)
                     /locus_tag="ROH59_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDX4806213.1"
                     /translation="MTNKHPSLFSPFMLTEKIKLRNRIVMAPMTTWSANPDGTISEQE
                     LEFYKRRSQNVGLVITGCTYVTPSGIGFTHEFAAYDDRFINSLEKLAAAAKSGGAPAI
                     LQIFHAGNKAIPELVPNYDVISASASSVKSGDFMKRVVQSREMTENEIQETIRAFGDV
                     TKRAIKAGFDGVELHGAHGFLLQNFFSPLFNQRNDRWGGDLEGRMRFPLAVLQEVKNV
                     VYEYATKPFAIGYRISPEESVTGGLRIEDTYKLLDRLISSGISYIHTSLVSINDSYPV
                     ESPNGPRTIELILNHIAGRVPVIAAGKIRTPSQAQEAISAGLPLVAIGKGLVINPEWV
                     TLAESGRSHEIQTALNPQRVPELTIPDKLWDQIQASKGTGWFPLMD"
     gene            complement(3496..4416)
                     /locus_tag="ROH59_003782"
     CDS             complement(3496..4416)
                     /locus_tag="ROH59_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4806214.1"
                     /translation="MKTVSIKHTYWDIAADIYFPDDFNSEKKYPAIISAHPIGSCKEQ
                     TSGSVYGAALAKAGFIVIAFNASFQGSSGGEPRYLEDPTMRVKDFSIVVDYLTTLPYV
                     DAGRIGVLGICGGGGYAINAAMTERRIKAIGTVTGANYGRLMREGFTAFNPIGALEAM
                     AQQRTDEANGAKLRVDDLLPSSPEAALEAGLTEIDLFEATEYYRSPRGCAPNGVNRSL
                     FSHQTVAVGWDAFHLAEVLLTQPLMVVVGDRVGAFGAYRDGCEIIGRAASKHKELVVV
                     EGYSHYDLYDKPEPVKQALDKLIPFYKTHL"
     gene            4573..5499
                     /locus_tag="ROH59_003783"
     CDS             4573..5499
                     /locus_tag="ROH59_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4806215.1"
                     /translation="MMKIEPSILPSLAWFALIVRAGSFSRAASEMGITRAALSQNLKS
                     LEERLNTKLIYRTTRNMSLTEEGQHLYEVLVSALGQIDDALKDVGDTQLEPTGLLRIN
                     SSRVAARMLVEPHIGEFLTRYPKTKIELIMDDGLSNIIADGCDVGIRLEQGLDEHMTA
                     IPVSPLIKLVTVASPDYLKEHGIPETPQELSNHNCLRLRHKSSGALSAWEFSNVVGGN
                     EEFEIEVSGKYISNDDESMIRMALNGTGIIQHLDFAIAEHINAGKLQPILEDWAVSFP
                     GFYIYVSSRVRMPSKVRAFIDFMVEKRVKIES"
     gene            5699..6592
                     /locus_tag="ROH59_003784"
     CDS             5699..6592
                     /locus_tag="ROH59_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX4806216.1"
                     /translation="MLKENFNELQIFLVVARERSFTKAAGKLGVSQSALSHAMKALEE
                     RLNIRLLTRTTRSVAPTEAGERIIACLEPRIDELEQELESLIQLNGTPSGNIRLSAGE
                     HAARSLVWPKLKPFLREYPEINVELVVDNGFVDIVEGRFDAGIRLGENVDKDMVAVRI
                     GPDMRMAVVGAPAYFAANPAPETPHELQNHRCINMRLPTAGGLYHWEFEREGKPLRVK
                     VDGQLTCSPLPERIDAALSGFGIACVPEDMVQEYIKSGKLIQVLQEWCPTFPGYYLYY
                     PSRKQHPPAFALLIDALRYTE"
     gene            complement(6623..7612)
                     /locus_tag="ROH59_003785"
     CDS             complement(6623..7612)
                     /locus_tag="ROH59_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDX4806217.1"
                     /translation="MQKRYLGKSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAV
                     ERGVTFFDTAEVYGPYLNEEVVGEALKPFRDRVVIATKFGFTFGDDNKQQILNSRPEH
                     IREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
                     TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPG
                     TTFGKDDYRSTVPRFAAQAIEANEKLVTLLGELAADKGVTSAQIALAWLLAQKPWIVP
                     IPGTTKLNRLEENLAAADIVLSQKDTQQITEALETIKIVGERYSPEHQARVGR"
     gene            complement(7639..8490)
                     /locus_tag="ROH59_003786"
     CDS             complement(7639..8490)
                     /locus_tag="ROH59_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDX4806218.1"
                     /translation="MQKVKLNNGIEMPLLGFGVFQMTDAAECERAVIDAINSGYRLID
                     TAASYQNEIQVGNALKQSGIARNELFVTTKLWLQDTSYEGAKAQFERSLNRLQLDYVD
                     LYLIHQPYGDVHGAWRAMEELQQAGKIRAIGVSNFHPDRLADLIAFNNVVPAVNQVEV
                     NPFNQQLQAVPWMQSRGIQPEAWAPFAEGKNGLFQHPVLTAIGEKYGKSVGQVVLRWI
                     YQRGIVSLAKSVRKERMEENINILDFELSPEDMLQITALDTATSAFFSHRDPAMVEWL
                     TGRKLDV"
     gene            9056..13303
                     /gene="fdeC"
                     /locus_tag="ROH59_003787"
     CDS             9056..13303
                     /gene="fdeC"
                     /locus_tag="ROH59_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like adhesin FdeC"
                     /protein_id="HDX4806219.1"
                     /translation="MSRYKTDNKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMENTTVTANNNVEKNVASLAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKNFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSENDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAITAEVNYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRE
                     RRMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTVSLGLVVSKATHGLK
                     NVQWEAPSLLAAGGKITGQGNQWQVTLPAYQAGKDNYYAISAIAYDNKGNASKRVQTE
                     VVISGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLRDAEGQPVTGMKDQIKTEL
                     TFKPAGNIVTRTLKATKSQAKPTLGEFTETESGVYQSVFTTGTQSGEATITVSVDDMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     LVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDANDNPVTGLNPDAPSLSGAAAAGSTASGW
                     TDNGDGTWIAQISLGTTAGELDVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTASEGATVSSWTEKGDGSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKTPTVKTTTELTFTV
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGEHNISASVNGAQKTVTVKF
                     NADASTGQANLQVDTAVQKVANGKDAFTLTANVEDKNGNPVPGSLVTFNLPRGVKPLT
                     GDNVWVKANDEGKAELQVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISSIE
                     VIGNRAVADGKTKQTYKVTVTDANNNLLKDSEVTLTASPENLVLTPNGTATTNEQGQA
                     IFTATTTVAATYTLTAKVEQADGQESTKTAESKFVADDKNAELAATSDVHSLVADGVT
                     TATLTVTLFSANNPVGGTMWVDIEAPEGVTEADYQFLPSKNDHFASGKITRTFSTNKP
                     GTYTFTFNSLTYGGYEMKPVTVTINAVPADTEGAEEK"
     gene            complement(13428..14285)
                     /locus_tag="ROH59_003788"
     CDS             complement(13428..14285)
                     /locus_tag="ROH59_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4806220.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLSAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKLPDEEVKL
                     RRHHLVRCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWTINRG
                     LYASFRYEGEWEHYPEWARNLYLMELPARGLARVNGSDIERFYYNENFVEIDSNNIVC
                     EIFIPVRPV"
     gene            14533..15402
                     /locus_tag="ROH59_003789"
     CDS             14533..15402
                     /locus_tag="ROH59_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDX4806221.1"
                     /translation="MEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLID
                     TAAVYGNEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSG
                     LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
                     NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQV
                     ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
                     EFVRGCLAVKIHD"
     gene            complement(15562..16155)
                     /gene="rclC"
                     /locus_tag="ROH59_003790"
     CDS             complement(15562..16155)
                     /gene="rclC"
                     /locus_tag="ROH59_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HDX4806222.1"
                     /translation="MERYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSARDILKQRSNESSSTLKTEY"
     gene            complement(16167..16403)
                     /locus_tag="ROH59_003791"
     CDS             complement(16167..16403)
                     /locus_tag="ROH59_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX4806223.1"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     NAIADMARKYNASSWKVTSMRIDNNSTATAVLYK"
     gene            complement(16512..17837)
                     /locus_tag="ROH59_003792"
     CDS             complement(16512..17837)
                     /locus_tag="ROH59_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HDX4806224.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKQLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGRRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     gene            18064..18918
                     /gene="rclR"
                     /locus_tag="ROH59_003793"
     CDS             18064..18918
                     /gene="rclR"
                     /locus_tag="ROH59_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RclR"
                     /protein_id="HDX4806225.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFVAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMMEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSREMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     gene            19444..20163
                     /locus_tag="ROH59_003794"
     CDS             19444..20163
                     /locus_tag="ROH59_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HDX4806226.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAE
                     KVAARMQDLTSFIVNTLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            20174..21601
                     /locus_tag="ROH59_003795"
     CDS             20174..21601
                     /locus_tag="ROH59_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="HDX4806227.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFAKTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDSVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQENKNG"
     gene            21594..22289
                     /locus_tag="ROH59_003796"
     CDS             21594..22289
                     /locus_tag="ROH59_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HDX4806228.1"
                     /translation="MDNRSEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLTQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGIENISQAEQAIVGVVYAEYGLTESGGVVLFSAAGRGRSLSLLP
                     ESSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
BASE COUNT         6104 a         4917 c         5490 g         6060 t
ORIGIN      
        1 ttacaaaaaa tgaaaatatt gcttttttga taagaagaaa aagacattca gtttcataag
       61 gttattggca atataacgtt caattcttac ttgcatttta tattagccag gaactttgcc
      121 ctgaggtgtt aggaatagtc ttaatgtgtt gtgtaatgga ctagtaaaaa aacaagttta
      181 aatgataaga aatagaatat aaaactatca taagtcataa ttaaagatga tttgccaatc
      241 agtaaggtgt tttaatggat taacatgccg cacaaaatgg ttatgggtgt tcattccaat
      301 aagtgatgga aaattaaaca ggtgtaagta cgtcatctgt ccggtaagcc ccctaagagc
      361 taaattaagt gaagttaaac gaagactgcc agttgtcaca ggaacgatgg cctctttgcc
      421 agggcactgc attcagtcat ctgtgcgcgt tactctaact ggcactcgaa cgtcggcgat
      481 ggggttaccg atggatctgg ccgttcctgt ggcgtaaacg tttttatgtc agtaccaaca
      541 gatttaccac atttatcatc ttaacagttt gagtgtaaat gcaggctgcg tcgcaaaggg
      601 aggaaactga gtggcgtgtt cagtctaaaa gagagttgat gccagcatac agggcgaagc
      661 tggtcaacaa gtcaacatta atataatgga atattcggag agaaacgtca ggcagttgac
      721 cttaaatgaa caggaagata catccccagg aaaattaatg ctggtgtaat aaatacacca
      781 acattaatcc ggtctgatta ttaatcagac aaatatcgtt aattcgtcga attttaaatc
      841 aacgtttttt cttacgaccc tgaacggcct taaaacgtgg attagattta caaatcacat
      901 acagccgtcc ttttcgcttc acaatctgac agtctggatg gcgttctttt gcggtacgca
      961 gagagttaag gactttcatc atgccccctt tttcgtgcta acaaaacgac caaaacgttg
     1021 ggtgaaccgt gcaacatttc cttctgatgc cactgttctc agcttccctg tatagaacgg
     1081 gtgcgatttc gaagagacat caattgttac gtacggatac gttacgccat ccagctcaat
     1141 ctcacggtct gttttgatag tcgagccgat tttaaagtac tcatcaacgc tggtgtcgtg
     1201 gaacaccaca gtacgatact caggatggat attgggtttc atcattttta cctgttatgt
     1261 tataacataa ccgtaaagat acatgctcat ccggatcatt tcaacaccca atcactgtga
     1321 ctatttgtgg gatgtggaat ttccgcaacg gggaagtctg gcattgttag cagccattgg
     1381 cgacgctccc ataaacgcct ggatgagtga ttgatgatgg tttcgctgag agtatggatt
     1441 tttcgagaat ggaggctatc tccactttac tggccgatga tttattgcag catgattgat
     1501 tacctgacaa tgtgtattcc tctcccacgg atataataat tacttacaaa aaagggagag
     1561 gatgcatatt ttaaatatca ctgaagtgaa cagtttattg ccgttattaa tagaaatgga
     1621 gaaataaata ggcgtattct acaattgcga caaaaacaac gatattaatc agtttatgac
     1681 tgatttgctg tactttattc tctttcattg gtacttcctc gctttaaaaa agagtgcact
     1741 tcgtaagtgc ccttatataa ataacgagtt tggtcaacca attttttgac atgtatcaca
     1801 aatttgaata gatgtattac atcggctatc ttttattgcc ccaacgtcat tgatatatgt
     1861 cgcctgaaat cagttacggg aatgagtctg atctcaagac tggcccagtc ctggcgttga
     1921 ttggcgctga ggagcatatc gcatctcatc gtaacgtcgt atctcctggg gtgttataca
     1981 agatatcgtt gtaggtaacc agggagagga attgagtcta ttaaaccgtc aactatgccg
     2041 gatacatact ggattacact gcaggcacgc cttgcgagag aacgtgccgc agtgacgggt
     2101 taattatctg aaagaatttg cgaggctgta tcggttactc attgatttga tagttttact
     2161 ctcgggagag taatcgatat ttaatccatt aacggaaacc agccagttcc tttcgatgcc
     2221 tgaatttgat cccatagttt atccggaatg gttaattcag gaacgcgttg tggattaagg
     2281 gctgtttgaa tttcatgact tctacctgat tcagctaaag tcacccattc tggatttatc
     2341 accagccctt taccgatcgc aacaagtggc aggccagcgg aaattgcttc ttgagcctga
     2401 gacggtgtgc gtattttacc tgcggcgatt accggcactc tgcctgcaat atgatttaaa
     2461 atcaattcaa tagttcgggg accatttggc gactcaacag ggtagctatc gttaatactg
     2521 accagcgagg tatgtatata cgaaataccg gatgaaatga gccgatcaag gagtttataa
     2581 gtatcctcta tccgcagtcc ccctgttaca gattcttcag gagatattct gtaaccgata
     2641 gcaaagggct ttgtcgcata ttcatagact acatttttta cttcctgtaa tacggccagc
     2701 gggaagcgca tacgtccttc aagatctcct ccccatcggt cattacgctg gttaaataga
     2761 ggggagaaga aattctgcag aaggaatccg tgcgcaccat gaagttcaac gccatcaaaa
     2821 cctgctttaa tcgccctttt tgtgacatct ccgaatgctc taatggtttc ctgaatttcg
     2881 ttttcagtca tttccctgct ttgtaccact ctcttcataa agtcaccaga ttttacgctt
     2941 gatgcgctgg cactaataac atcgtaattt ggcacaagct ccgggatggc tttattaccg
     3001 gcgtggaaaa tctgcaaaat agccggagca ccgccacttt tggctgcagc tgctaacttt
     3061 tcaaggctgt taatgaaacg gtcgtcatac gcggcaaatt catgagtaaa cccaatgccg
     3121 cttggcgtga cataggtaca tcctgttatt actaaaccaa cattttgtga gcgacgttta
     3181 taaaattcga gttcttgctc agagatggtt ccatcaggat tagctgacca ggttgtcata
     3241 ggagccataa cgatacgatt acgtagcttt attttttctg tcagcataaa aggagaaaac
     3301 aatgatgggt gtttatttgt cataacaata cctcaaatgt ttatctgatt ttaatgcgta
     3361 taatcttaat aagttgagtt gctacttttt gatgcttttt tcctttaata gaattctttt
     3421 tgagtaattt tattattgtc gtgtagtcaa taaaggataa atgtcaggga gataatgaat
     3481 ctccctgcaa ggttattaca aatgtgtttt gtaaaaagga attaatttat cgagcgcctg
     3541 tttcacaggt tctggcttat catacaggtc gtaatgtgaa taaccttcaa ccacgaccaa
     3601 ctctttatgt tttgaggctg cacgaccaat aatttcgcag ccgtcacgat aggcaccaaa
     3661 agcgcccact ctatcgccta ctacaaccat tagtggttga gttaacagga cttctgcaag
     3721 atgaaaagca tcccagccca cggcaacagt ctgatgtgaa aatagcgaac gatttacccc
     3781 attaggcgca cagcctcgtg gcgaacgata atattctgtt gcttcaaaaa ggtctatttc
     3841 tgttaatccc gcttcaagag ctgcttccgg agaagaagga agcaaatcat ctacgcgaag
     3901 ttttgcgccg ttagcttcgt ctgttctttg ttgcgccatt gcttcgagtg ctccgatagg
     3961 attaaacgct gtaaatccct cacgcataag acgcccgtag tttgcacctg tgacagtacc
     4021 aatggcttta atccgacgtt ctgtcattgc ggcattaatg gcatatccac ctccaccaca
     4081 aatacccagt acaccaatac gcccggcatc aacgtaaggt aaggtggtaa ggtaatcaac
     4141 gacaatgctg aagtctttta ctcgcattgt tggatcttcc agataacgcg gttctccacc
     4201 gctgcttccc tgaaaactgg cattaaaagc aatgacgata aagccagctt ttgccagggc
     4261 ggcaccatac acactacccg atgtctgttc tttgcagctt ccaattggat gggcactgat
     4321 aatggcagga tacttttttt cactattaaa atcgtcaggg aaatagatat cagcagctat
     4381 atcccagtaa gtgtgtttta ttgaaacagt tttcatttca agctccaggg atttgcctaa
     4441 acagatttaa atatcatttc tattatccgc aactggcatt cgtgttcata tcgcgaacgg
     4501 cgtaatagta tgacttgtat tggttatcat caatggtcta atatctatca cagtgttaag
     4561 ttaaggttta caatgatgaa aatagagcct tcaattttgc cttcccttgc ctggtttgcg
     4621 ctgattgttc gtgccggcag tttttccaga gcagcctctg aaatgggtat tacgcgggcc
     4681 gcattgtccc agaatttaaa atctcttgag gaacgtctta acaccaagct gatataccgt
     4741 acaacccgca atatgtcgct tactgaggaa ggacagcatc tgtatgaagt gctggtgtcg
     4801 gctttggggc aaattgatga tgcgttgaaa gatgtcggtg atacccaact tgaacctaca
     4861 ggactgttga gaataaattc ctcccgtgtt gcagcaagga tgcttgttga gcctcatatt
     4921 ggcgagtttc ttactcgtta ccccaaaaca aagatagaac tcattatgga tgacggttta
     4981 tctaacatta ttgcggacgg ctgtgatgtg ggcatacgtc ttgagcaagg actggatgag
     5041 catatgactg ccattcctgt ttctccgctt attaaactgg ttactgtggc atcgccagat
     5101 tatttaaaag aacacggtat tcctgaaact cctcaggaat tgagtaacca taattgtctt
     5161 cggttgcggc ataaaagtag cggtgcactc tcagcatggg agttttcgaa tgttgtgggg
     5221 ggtaatgaag agttcgaaat agaggtgtca ggtaagtata tttctaatga tgacgaaagc
     5281 atgatacgaa tggcgctgaa tggaacgggt atcattcaac atctggattt tgcaatcgct
     5341 gaacatatca atgcgggcaa gttacagccg attcttgagg attgggccgt ttcatttcct
     5401 ggattttata tatatgtttc atctcgggtg agaatgccct ctaaagttcg tgcttttatt
     5461 gattttatgg tggagaaaag agtaaaaata gaaagttaat gatgtgtgtc agaatatcgg
     5521 taagaagaat ggcgcaatcg tgagaatacg tttattcata ataaatctcc tgaaagttta
     5581 gaattatttt cgatacagcc agattatcat tgttactaat aatgtggtta aaataatagc
     5641 atctatgccc cccttcatga gtgtctgtga agaggatgct tctacaagga aatcgccaat
     5701 gctcaaagaa aacttcaacg aactgcaaat ctttcttgtg gtggcaagag agcgaagttt
     5761 taccaaagca gcgggcaaac tcggcgtctc tcagtctgca cttagccatg caatgaaggc
     5821 tctggaggaa aggctcaata tccgcctcct gacacggact acccgcagtg tggctcccac
     5881 agaagcgggg gagagaatca ttgcctgcct tgaaccgcgt attgacgagc ttgaacagga
     5941 actggaatca cttattcaat tgaacggcac gccctccggg aatattcggt tatctgccgg
     6001 ggaacatgcc gcgcgaagtc tggtctggcc gaagctaaaa ccttttctca gagagtatcc
     6061 cgaaatcaat gtcgaactgg tggtggataa cggttttgtc gatattgttg aaggccgttt
     6121 tgatgccggg atacgactgg gtgaaaatgt tgataaagat atggttgcag tcaggattgg
     6181 accagatatg cggatggctg tggtgggagc tccggcgtat tttgctgcaa accctgcgcc
     6241 tgaaacgcct catgagctac aaaatcatcg ctgcatcaac atgcgtttgc caactgccgg
     6301 tgggctttac cactgggagt tcgagcgaga agggaaaccg cttcgcgtta aggttgatgg
     6361 gcaactgacg tgtagtccat tgccagaaag aattgatgcc gcgttatcag ggtttgggat
     6421 cgcttgtgtc cctgaagaca tggttcagga gtatataaag tcaggcaagc ttattcaggt
     6481 gttacaggag tggtgtccaa cttttcctgg gtattatctt tactacccca gccgcaagca
     6541 gcatccgcca gcttttgcgc tgttgatcga tgcgcttcgc tacaccgaat aacgggtcct
     6601 ttatcctgga cccgtttggg tattagcggc ctacgcgtgc ctgatgttca ggcgagtaac
     6661 gttcaccgac gattttaatt gtttccagcg cctcggttat ctgctgcgta tctttctgcg
     6721 aaagaacaat gtcagcagcg gccaggtttt cttccagccg gttcagttta gtggtgccag
     6781 ggatgggaac aatccacggc ttttgtgcta atagccatgc cagtgcgatt tgtgcagacg
     6841 ttaccccttt atctgcagcc agttcaccta acaaggtgac cagtttttca ttggcttcaa
     6901 tggcttgtgc tgcgaaacgc ggtacggtgc tgcggtaatc atctttgccg aaagtggttc
     6961 ccggcttaat cgcccctgtc aggaaacctt tacctagtgg gctgaagggg acaaaaccaa
     7021 ttcccagttc ctccagcaac ggcagaattt cctgttcagg ctcacgccac cacatggaat
     7081 attcgctttg cagggcggtg acaggttgta ccgcatgtgc acgacgaatg gtttgtgctc
     7141 ctgcttcaga caggccgaaa tgtttgacct taccttctgc gatgaggtct ttcaccgttc
     7201 ctgcaacatc ttcaatagga acatctggat caacacggtg ttgatacagc aggtcaataa
     7261 catctgtttt cagacgacgt aatgatcctt caacggcttc acggatatgt tccggacggc
     7321 tgtttaaaat ctgctgctta ttatcatcgc cgaaggtaaa accgaattta gtggcaatta
     7381 ccacgcggtc acgaaacggt tttaaggctt cgccgaccac ttcttcattc agatacggac
     7441 catacacttc ggcggtatcg aagaaggtga caccacgttc aaccgcagca cgaataagtt
     7501 cgatagcctg acgggtatcg gtcgccgggc cgtagccgtg gcttaagccc atgcaaccga
     7561 gcccaagggc ggagacttcg agtccggatt tacccagata acgtttttgc attgaatgaa
     7621 tacctctttt atcgcggctt aaacatcaag tttgcggcca gtcagccatt ccaccattgc
     7681 gggatcgcgg tgagagaaga acgcgctggt tgcggtatcc agggcggtaa tttgcagcat
     7741 atcttcaggg ctgagttcaa aatcgagaat gttgatgttc tcttccatgc gttcttttcg
     7801 cactgatttt gccagtgaaa caatgcctcg ttggtagatc cagcgcagaa caacctggcc
     7861 cacgcttttg ccatacttct cgccaattgc cgtgagaaca ggatgctgga acagaccatt
     7921 tttcccttcc gcaaacggtg cccaggcttc tggctgaatg ccacgacttt gcatccaggg
     7981 aacggcctgt agctgctgat tgaaagggtt aacttcaacc tggtttaccg ccggaacgac
     8041 gttattaaaa gcgataaggt ctgccagtcg gtcaggatgg aagttactga cgccaatagc
     8101 gcgaatttta ccggcctgtt gcagctcttc catggcacgc caggctccgt ggacatcgcc
     8161 atatggctgg tgaatcaagt acaggtcaac gtaatcaagt tgcagtcgat tcagagagcg
     8221 ttcgaactgg gctttggccc cttcgtaact ggtatcctgc aaccagagtt tcgtggtgac
     8281 aaagagttcg ttacgggcga taccgctttg tttcagtgcg ttcccgacct ggatttcatt
     8341 ttgataagag gcggcggtgt caatcagtcg ataaccgctg ttaatagcgt caatgaccgc
     8401 tctttcgcat tcggcggcat cggtcatctg aaatacacca aagcccaaca ggggcatttc
     8461 aataccgttg ttcagtttta ctttttgcat ggtgttatcc ttccgttatc gttcatgaga
     8521 agcataacgt aaagggaaga gctcgattag acggcaggat ttgtcagggg ttatgaacaa
     8581 aattcataaa tctgtttgag ggttgagatt agtcgtgcaa gttcgatatc cccggaattt
     8641 acagtccgat gaataaaaat gaatgtccat aaaaaatata ttggtttatc ccggcgtata
     8701 tacttacttc gacgtactcc caatagcagt taattaaaga cgggtcatta ttattcactc
     8761 tggataatga attattcact gcccgcagag taagaaatat aacttaagta tctatttaat
     8821 gacttgcaca aaaagctaaa tttttaccca taaataaaaa tataatcccg cgcccaacca
     8881 cctgatgagt ggctacagac actggatata ttaggtggcg gtgtactttc ttacataaag
     8941 gtatttcctt ttctgtggaa aaggaaaccg ggaaatcccc ggtttttctg acaagcagac
     9001 gccattattt gtgtctgcct atgttcgtta attcgttcat caggaaatta tctcaatgtc
     9061 acgttataaa acagacaata aacagccacg atttcgttat tcagttctgg cccgctgcgt
     9121 ggcgtgggca aatatctctg ttcaggttct ttttccactc gcagtcacct ttacgccagt
     9181 aatggcagca cgtgcgcagc atgcggttca gccacggttg agcatggaaa atactacggt
     9241 aactgctaat aataacgtgg agaaaaatgt cgcgtcgctt gccgctaatg ccgggacatt
     9301 tttaagcagt cagccagata gcgatgcgac acgtaacttt attaccggaa tggccaccgc
     9361 taaagctaac caggaaattc aggagtggct cgggaaatac ggtactgcgc gcgtcaaact
     9421 gaatgtcgat aaaaatttct cgctgaagga ctcttcgctg gaaatgcttt atccgattta
     9481 tgatacaccg acaaatatgt tgttcactca gggggcaata catcgtaccg acgatcgtac
     9541 tcagtcaaat attggttttg gctggcgtca tttttcagaa aatgactgga tggcgggggt
     9601 gaatactttt atcgatcatg atttatcccg tagtcatacc cgcattggtg ttggtgcgga
     9661 atactggcgt gattatttga aactgagcgc caatggttat atccgggctt ctggctggaa
     9721 aaaatcgccg gatgttgagg attatcagga acgcccggcg aatggctggg atattcgtgc
     9781 tgagggctat ttacctgcct ggccgcagct tggcgcaagc ctcatgtatg aacagtatta
     9841 tggcgatgaa gtcgggctgt ttggtaaaga taaacgccag aaagatccac atgcgattac
     9901 cgctgaagtg aattacacgc cagtgcctct tctgaccctg agtgccgggc ataagcaggg
     9961 caagagtggt gagaatgaca ctcgctttgg cctggaagtt aattatcgga ttggcgaacc
    10021 tctggaaaaa caactcgata cagacagcat tcgcgagcgt cgaatgctgg caggcagccg
    10081 ctatgacctg gttgagcgta ataacaatat cgttcttgag tatcgcaaat ctgaagtgat
    10141 ccgtattgct ctgcctgagc gtattgaagg caagggcggc cagacggttt ccctggggct
    10201 tgtggtcagc aaagcaactc acggtctgaa aaatgtgcaa tgggaagcgc cgtctttgct
    10261 ggccgcaggc ggaaaaatta cggggcaggg caatcagtgg caagtgacgc tcccggctta
    10321 tcaggcaggc aaagacaatt attatgcgat ttcagcgatt gcctacgata acaaaggcaa
    10381 tgcctcgaaa cgtgtgcaga cagaagtggt tattagcgga gctggtatga gcgccgatcg
    10441 tacggcgtta acgcttgacg gtcagagccg tattcaaatg cttgctaacg gtaatgagca
    10501 aaagccgctg gtgctgtctc tgcgcgacgc cgagggtcag ccagtcacgg gcatgaaaga
    10561 tcagatcaag actgaactaa ccttcaaacc ggctggaaat attgtgactc gtaccctgaa
    10621 ggccactaaa tcacaggcaa agccaacact gggtgagttc accgaaactg aatcaggggt
    10681 gtatcagtct gtctttacta ccggaacgca gtcaggtgag gcaacgatta ctgttagcgt
    10741 tgatgacatg agcaaaactg tcactgcaga actgcgggcc acgatgatgg atgtggcaaa
    10801 ctccaccctg agcgctaacg agccgtcagg tgatgtggtt gctgatggtc agcaagccta
    10861 cacgctgaca ctgacagcgg tggactccga gggtaatccg gtgacgggag aagccagccg
    10921 cctgcgactt gttccgcaag acactaatgg tgtaaccgtt ggtgccattt cggaaataaa
    10981 accaggggtt tacagcgcca cggtttcttc gacccgtgcc gggaacgttg ttgtgcgtgc
    11041 cttcagcgag cagtatcagc tgggcacgtt acaacaaacg ctgaagtttg ttgccgggcc
    11101 gcttgatgca gcacattcgt ccatcaccct gaatcctgat aaaccggtgg ttggcggtac
    11161 agttacggca atctggacgg caaaagatgc taatgacaac cctgtaactg gcctcaatcc
    11221 ggatgcaccg tcattatcgg gcgcagctgc tgctggttct acggcatcag gctggacgga
    11281 taatggcgac gggacctgga ttgcgcagat ttctctcggc actacggcgg gtgaattaga
    11341 cgttatgccg aagctcaatg ggcaggacgc ggcagcgaat gcggcaaaag taaccgtggt
    11401 ggctgatgca ttatcttcaa accagtcgaa agtctctgtc gcagaagatc acgtaaaagc
    11461 cggtgaaagc acaaccgtaa cgctggtggc gaaagatgcg catggcaacg ctatcagtgg
    11521 tctttcgttg tcggcaagtt tgacggggac cgcctctgaa ggggcgaccg tttccagttg
    11581 gaccgaaaaa ggtgacggtt cctatgttgc tacgttaact acaggcggaa agacgggcga
    11641 gcttcgtgtc atgccgctct tcaacggcca gcctgcagcc accgaagccg cgcagctgac
    11701 tgttattgcc ggagagatgt catcagcgaa ctctacgctt gttgcggaca ataaaactcc
    11761 aacggttaaa acgacgacgg aactcacctt caccgtgaag gatgcgtacg ggaatccggt
    11821 caccgggctg aagccagatg caccagtgtt tagtggtgcc gccagcacgg ggagtgagcg
    11881 tccttcagca ggaaactgga cagagaaagg taatggggtc tacgtgtcga ccttaacgct
    11941 gggatctgcc gcgggtcagt tgtctgtgat gccgcgagtg aacggccaaa atgccgttgc
    12001 tcagccactg gtgctgaatg ttgcaggtga cgcatctaag gctgagattc gtgatatgac
    12061 agtgaaggtt aataaccaac tggctaatgg acagtctgct aaccagataa ccctgaccgt
    12121 cgtggacagc tatggtaacc cgttgcaggg gcaagaagtt acgctgactt taccgcaggg
    12181 tgtgaccagc aagacgggga atacagtaac aaccaatgcg gcagggaaag tggacattga
    12241 gcttatgtca acggttgcgg gagaacacaa tatttccgct tcggtgaatg gtgctcagaa
    12301 gacggtcacg gtgaaattca acgcggatgc cagcaccggt caggcaaacc tgcaggtaga
    12361 caccgccgtt caaaaagtgg caaacggcaa agatgccttt acgctgacgg cgaacgttga
    12421 ggataaaaat ggtaaccctg ttccagggag cctggtgacc tttaatctgc cccggggtgt
    12481 caagccgctt acaggcgata atgtgtgggt gaaagccaac gatgagggga aagcggagtt
    12541 gcaggtggtt tccgtgactg ccggaaccta tgagatcacg gcgtcagcag gaaatgacca
    12601 gccttcgaat gcgcagtctg taacgtttgt ggccgataag actacggcga ccatctccag
    12661 tattgaggtg attggcaacc gtgcagtggc ggacggcaaa accaaacaga cgtataaagt
    12721 tacggtgact gatgccaata acaacctgct gaaagatagc gaagtgacgc tgactgccag
    12781 cccggaaaat ttagttctga ctcccaatgg gacggcgaca acgaatgagc aagggcaggc
    12841 tattttcacc gccacgacca ctgtcgcagc gacatataca ctcacggcga aagtggaaca
    12901 ggccgacggt caggaatcga cgaaaactgc cgaatctaaa ttcgtcgcgg atgataaaaa
    12961 cgcggagctc gccgcaacat ctgatgtgca ttctctggtg gcggatgggg taacgacagc
    13021 aacactgacg gtaaccctgt tctcggcaaa caacccggta ggaggaacca tgtgggtcga
    13081 cattgaggct ccggaagggg tgacagaggc ggattatcag ttcctgccgt cgaaaaatga
    13141 ccatttcgcg agcgggaaaa tcacgcgtac atttagtacc aacaagccag gtacatacac
    13201 attcacattc aactctttga catatggagg gtatgaaatg aaacccgtga ctgtgacaat
    13261 taacgccgtt cctgcagata ctgaaggtgc tgaggagaaa taaaaacgac gatgtaataa
    13321 ataataatgg cgttgacatg cgcagcgcca ttatttactg aatacctacc ctggcaccga
    13381 ttagacggtg gcagggtagg gtaaatctta tgtgatggag ttacaggcta aaccgggcga
    13441 acggggataa aaatttcgca aacaatgtta ttgctatcaa tttcgacgaa gttttcattg
    13501 taataaaatc gctcaatatc actgccgttc actctggcta accccctggc aggtaattcc
    13561 atcagataga ggtttcgcgc ccattcaggg tagtgctccc actcaccttc atagcggaaa
    13621 gaggcataca gtcctcggtt aattgtccac tctttcggca tctctgaatc ggtttgtttg
    13681 cataccgtac cggcaaaagt ttcaactgtg agcaaatcga ccgattttgt tgatggttcg
    13741 aacgtggaga cgaaatagat atccgtctta aaattcttca tacatctgac taaatgatga
    13801 cgtcgcagtt tgacttcttc atccggtaat ttattcgaca cttcaatatc atatttaaat
    13861 gaattgccaa aaataggtgt ctcaggaaag ttgactaatc tacactccgt cttttgctgt
    13921 tgacgtatta aaaaagaagg gaagatattt gcgagatccc aataatcacg gtggcggtat
    13981 tcacggggag agcagccgaa taacttttta aattcgcggc tgaatgactg ctgtgaatca
    14041 aaatgcaaag agagtgcaat atcaagcata gatttcgcgg agagccggac aagaatggcg
    14101 gcacgacaaa gccttcgttt gcgaatgtat tctcccaaag gcacatgcat gaaatttcgg
    14161 aacagaagct ggatgttgcg tctgctgtag ccagatttct gtgcgatatc ttcgattgaa
    14221 atagggtgct caagattgca ctcaatccac tccaggagct gctgtagaat cttctgcctg
    14281 atcatcacat actccgttaa ttctttgtca tatcgcacat tttcgttatg tcctgggccc
    14341 taagtgtatc aaaaacagca agtcccaagg caaaagcact gatagcgtct gcttcattgc
    14401 cccaaaaata gagaggtttc agtcctacat tattaatgaa ttttttgcat aagtgatatc
    14461 aaaatccaca tactaatttg aggttacgtt ttaacgtaga ctcattgttc atacctaatg
    14521 gagggactga cagtggaatt ttccgtatta agtaacaatc tgaaaatgcc gatgatggga
    14581 tttggtgttt ttcaggttac cgataaagac gtgtgcaaac agtcagtgtt gaatgctatc
    14641 cgcacgggtt atcgactcat cgacactgca gcggtatacg gtaatgaaga tgccgtcggt
    14701 gaagccgttc gtgaagccat atctgaaggt ttatgtaccc gagaagagtt atttataacg
    14761 tctaaattgt gggtgcagga tatgttgaat caggatattg cagcagcagg tattgaagca
    14821 tcattaaaaa aatcggggct agaatacttc gatctctatt tattgcacca ggccatgcgc
    14881 gattatttta gtgcgtggcg tgcactcgaa gatgcctatg aagagggcaa attaaaagcg
    14941 attggggttt ccaatttcta ccctcatgtt ctggcgaact tttgtgaaac ggtaagagtt
    15001 aaaccgatgg tcaaccaggt cgagttgcat ccctattttg cccaaccaga ggcgctggca
    15061 accatgaagt attataacgt gcagcctgaa gcatgggctc cgttaggtgg tggacgacat
    15121 aaaccctttg aaaataatct gcttcagagt attgcagatg cccatcaaaa atcgatttct
    15181 caggtcattc tgcgttggaa tattcaacgg ggagtggtcg ttattccgaa atcgacacat
    15241 caacagcgta tcgaagaaaa ttttgctatc tgggatttct cactgacaga gaaagaaatg
    15301 gcgcaaatta gttcgctaga tttgggttat gttggggaat cggtaaaaca ttttaatcct
    15361 gagtttgttc gtggttgtct tgctgtaaaa atacatgatt gatattaatc acttatttta
    15421 cctgagacga caaaaatttt ttaacagggg agtgatattg atcgtcactc tgtcatatct
    15481 ccggtaatat ggcgtcaggc ttcatcaaca gaaagggggc ctgacgcctg aaaaagtgaa
    15541 caacagacag tgttcggatt atcaatattc agtttttaac gttgaactgg attcattact
    15601 gcgttgttta agaatatccc gtgccgaatc tgccattatc atgacagcac ctgccagcat
    15661 cagagtatct ttcaatacca gacgaccagc accggataaa taagggaaac catgatgagc
    15721 atcacccaat gcgggtaccc atgcctccgg agtggtgatt aaaaatgaga gtgttaccag
    15781 cggcgtggta aatgccatca gcccacccaa taaacctaac cagcgattga caggattagc
    15841 caaaaccagc agagcaataa tcacctccac gacgccaaga ccgttggaaa aaccataggt
    15901 attattagcc gtttgccatg ctcttgcttc tggtttgtat tcgccttcgt gagtcagata
    15961 ctgtttatag tcttccgggt gttcataaaa gaacgacatt agtggactgt ttgcgacgaa
    16021 tggtgtaatg ctgtctgcct cgtaagggac aaactttaat aacccaatcc acataaaaac
    16081 aatcgcaatg ctcagacgaa tcaatgtcag gccaatttta tctccccgac ttaacaggtg
    16141 caggtatctt tccattgtaa acatccttat ttatacaata ctgctgttgc ggttgaatta
    16201 ttatcaattc gcatcgatgt aactttccag gatgaagcat tatattttct ggccatatca
    16261 gcaatggcat tctcaagaac tgtcggtgat gctgatactg atgagacgct gatatgtttc
    16321 agaattattt tatcatctgc attggtggaa aatgccataa cgccagataa tagtgttgca
    16381 aataaaacag attttttaaa catataaaat accatcaatg aagtgattaa gaatttataa
    16441 agtaacaggg aattaataag attcttttct ctgagacgcc agaatatttg ttctggcgtc
    16501 tgattttgag tttatttgac taatgaaaat agatcattga gtgattcgct catcgacgga
    16561 tgagtaaata tctgatcgcg taatatgcta taaggcagcc cggcatccat caccattttc
    16621 actatattga tcatctcgtg ggagtcaaca cacagcagtg atgcccctaa tatacgttgg
    16681 gttttattat caacaatcgc ttttaatacc ccacgagtat cattcatcac tctggcacgc
    16741 ggaattgcag ctacaggcaa tgtcaccacc tgaatatcag caccactctc tctggcctgt
    16801 tcttctgtca taccaaccct ggacagtggc ggtgtcatga atacggaata aggcacattt
    16861 ttccgatcat cagtactacg tctgccttct cccagcaact catcacgcac aatgcggtaa
    16921 tcatccagtg aaatataagt aaattgcagc ccgccggtaa catctcccat cgcccaaata
    16981 ttgtctgcgg tggtatgtaa ttgcttgtca acgacaattg ccccgcgttc gtttactgcg
    17041 atacctgcat tttctggatg taacgaagcg gtagccggtt gacgaccgga agctattaac
    17101 agtgcatcca ccgccagttg ggcgtgttcg ctatgcactt gcacttgatt ttcatggtga
    17161 ctgattcgct ccacatgggc attgaggatt atatcgacgc cctgatcgcg taaaatcgtc
    17221 gcgatattat cagcaatatc ccgatcttcc cgaggcaaaa acagcgaagc tgcctctaaa
    17281 atggttactt tgctgccaaa attagcgaac atagaggcga actcaacgcc aatatatccg
    17341 ccgcccaaaa tacctaaatg cccaggcaat tcttttagat taagtaatcc ggtgctgtca
    17401 tatactcctg gcgtggtggt aattccagga attggcggaa ccacggtttg tgcaccggta
    17461 ttaataaaaa ttttctcgcc atgaatttcc agatttccct caggccgatg aacacgcagg
    17521 ctatgattat tgataaactc cgcctggccg tcgatcacgt cgatattggg catatccgca
    17581 agattatgaa aattcttatt acgtaaaaaa ttaaccactt catttttacg ctgtatggca
    17641 cggacaaaat ctgtgtgctg ctgtgcgtca tgaaccaatg ttttggttgg gatacagccg
    17701 atattaatac aggtcccgcc atacattgca tttgattgtt cgatgagagc cacacgccaa
    17761 cctgcttttg ccagcgtgac ggctaatgtt tttccagcct tgccaaaacc aataataact
    17821 gcctgatatt tattcatgat gatttcctgt cgaaacgcgt tcatttgaca tcatgactat
    17881 agacgcaaaa gagcaaataa catttcttca caacgcttga tattttgtct tatcgtctgg
    17941 tattttcttt ttcttaatca gaatcacaaa acaaaaatca tgattaacta tttgatggta
    18001 ttagattaat tattgactaa gattgttggt gtttgtaatc caaaaaccac tcaggagtct
    18061 gatatggatg ctcttagccg tttgttgatg cttaacgctc cacaaggaac gatcgataag
    18121 aattgcgtgt taggaagtga ctggcaactt ccacatggtg ccggggagtt gtcggttatt
    18181 cgttggcatg cgttaacgca aggagcggcg aagctggaaa tgccgacggg agagattttt
    18241 acattacgcc cgggaaatgt ggtcctgcta ccacaaaatt cagctcatcg cctgagtcat
    18301 gtcgataatg aatcgacctg tattgtctgt ggaactcttc ggctgcaaca ttcggcgcgt
    18361 tattttttaa cgtctttgcc ggaaacgctg tttgtagcac cagtgaacca tagcgtggaa
    18421 tataactggc tgagggaggc gatcccgttt ttacaacagg aatccagatc ggcaatgccg
    18481 ggagtggatg ctctgtgtag ccagatctgc gctacattct ttaccctcgc ggtgcgtgag
    18541 tggattgcac aggttaatac agagaaaaac attctcagtt tgcttctgca tccacgtctt
    18601 ggtgcggtaa tacagcaaat gatggaaatg cctggacacg cctggaccgt cgaatcgctg
    18661 gccagcatcg cccacatgtc ccgggcaagt tttgcccagc ttttccgtga tgtttccgga
    18721 accacgccgc tggctgtatt aacaaagttg cgtctacaaa tagcggccca gatgttttcc
    18781 cgggaaatgc tccctgttgt ggtgatcgct gagtcagtag gctatgccag tgaatcatct
    18841 tttcacaagg cgtttgtccg cgagtttggt tgtactccgg gagaatatcg ggaaagggtg
    18901 agacagcttg caccctgaat aaaaccgcca gaaatcaggg caaagataat ccgcattccg
    18961 ggagttgtga gcctttcaac tatttctatt tctaacggtg gttttgggtt ttatatattt
    19021 ttttgatgga ctctagctca gtttttaaat aaaaatgcaa actaaattgc ttcaattaaa
    19081 taaaatcccg actattactt gatgcgtgat tattgtcggt gatttttttg tacaccatca
    19141 gtgtatatct caataacccc tgaataagta gctctgaata ggtataaggg atgtagcctt
    19201 tttaaatgga tttcttatgc caaaaatgat cgtcgatttc cctataaaat gtgagcgatg
    19261 ccgaaagaaa taaaattagt tattgcattt gaagtttaga tgaaagatta tcatttgtca
    19321 tacaaatgag aggtggtatg ttgctagcca attaaaaaag aacgccatat ttattgatga
    19381 ttgatccccc ggaaggaggg aaccatcggg cataaatggg catgaagtaa tggagtatta
    19441 gttgtgaatg tcaatttctt tgtcacctgt attggtgacg ccctgaaatc aagaatggca
    19501 cgagactccg tgctgctact ggaaaaactc ggctgtcgcg taaatttccc ggagaaacag
    19561 ggatgctgcg gtcagcctgc gatcaatagt ggttatatca aagaagcgat tccagggatg
    19621 aaaaatctga tcgccgcact ggaggataac gacgatccca ttatttcacc ggctggctct
    19681 tgcacctatg ccgtaaaaag ttacccgacg tatctggcgg atgaacctga atgggcatca
    19741 cgtgccgaaa aggttgccgc gcgtatgcag gatctcacct cttttattgt taatacatta
    19801 ggggtagtcg atgtaggtgc cagtttgcaa gggagagcgg tgtatcaccc atcttgtagc
    19861 ctggcccgta agctgggggt gaaggacgaa ccacttacgc tgctgaaaaa tgtgcgtgga
    19921 ctggagctgt tgacctttgc tgaacaggat acctgctgcg gatttggcgg cacgttctcg
    19981 gtcaaaatgg ccgaaatatc cggcgagatg gtgaaagaaa aggttgcgca cctgatggaa
    20041 gtccgccctg agtatttaat tggtgctgac gtgagttgcc tgctgaacat cagtggacga
    20101 ttacaacggg aagggcagaa agtcaaagtg atgcatattg ctgaagtgct gatgagccgc
    20161 tgaggatata aagatgtcga tcaaaaccag taatacagat tttaagacac gcatccgtca
    20221 gcaaattgaa gatccgatca tgcgcaaagc ggtggcaaac gcgcagcagc gtattggggc
    20281 aaatcggcaa aaaatggtcg atgaattggg gcactgggag gagtggcgcg atcgggccgc
    20341 ccagatacgt gatcatgttc tgagtaatct cgacgcttat ctgtaccagc tctcagaaaa
    20401 agtgacacaa aacggcggtc acgtctattt tgcaaaaacc aaagaagacg ccacccgcta
    20461 cattttacag gttgcccaac gcaaaaatgc ccggaaggta gtgaaatcta aatcgatggt
    20521 gaccgaagag attggtgtca atcatgtgtt gcaggatgcc gggattcagg tgattgaaac
    20581 cgatctgggt gaatatattc tccagctgga tcaagatccg ccctctcatg ttgtggtccc
    20641 ggcaattcat aaagatcgcc atcagatccg tcgagtgcta cacgaacgtc tgggctatga
    20701 ggggccggaa acgcctgaag cgatgacctt attcattcgg caaaaaatcc gcgaagattt
    20761 cctcagtgct gaaataggta ttaccggctg taatttcgcg gtggcagaga ccggttcggt
    20821 atgcctggtg accaatgaag gtaatgcgcg aatgtgtacc acgctgccta aaacgcatat
    20881 tgcagtgatg ggaatggagc gtattgctcc cacgtttgca gaggtagatg tattgatcac
    20941 catgctggcg cgcagtgccg ttggtgcacg tttgacggga tacaacacct ggctgacagg
    21001 accacgcgaa gcggggcacg ttgatggtcc tgaagagttt catctggtta ttgtcgataa
    21061 cgggcgttct gaggtgctgg cctctgaatt tcgggatgtg ctgcgctgta ttcgttgcgg
    21121 ggcttgtatg aatacttgtc cggcatatcg ccatattggc ggtcatggat atggctctat
    21181 ttatccaggg ccaattggtg cggtgatttc cccgttactt ggcggctata aagattttaa
    21241 agatttaccc tacgcctgct ctttatgcac cgcttgtgac agcgtgtgtc cggtgcgtat
    21301 tccgctgtca aaactgattt tgcgtcatcg tcgggtgatg gctgaaaaag ggatcaccgc
    21361 aaaagcagag caacgggcga taaaaatgtt cgcttatgcc aatagtcatc caggattgtg
    21421 gaaagttggg atgatggctg gtgctcatgc ggcaagctgg tttatcaatg gcggcaaaac
    21481 accactcaaa tttggcgcga ttagcgactg gatggaagca cgcgatcttc ctgaagctga
    21541 cggagagagt ttccgtagtt ggtttaagaa acatcaggcg caggagaata agaatggata
    21601 atcggagcga atttttgaat aacgttgctc aggcactggg tcgcccgctg cgacttgaac
    21661 cgcaagcaga agatgcgccg cttaacaact atgctaacga gcggcttacc caacttaccc
    21721 aacaacagcg ctgtgacgcg tttatccagt ttgccagcga tgttatgttg acgcgctgtg
    21781 aactgaccag cgaggcgaag gcggcagaag ctgcaatacg tctgtgtaaa gagctgggag
    21841 atcagtcggt cgtgattagc ggtgacacga ggctggagga attggggatt agcgaacgtt
    21901 tgcagcagga atgcaatgcc gttgtttggg atccggcgaa aggtattgag aacatatcac
    21961 aagcagagca ggctatagtg ggcgtcgtat atgctgaata tggtttaacc gaatcgggag
    22021 gcgtggttct tttttccgcc gccgggcgcg ggcgttcatt gagcctgctc ccggaatctt
    22081 ctctttttat cctgcgtaaa agcacaatcc tgccgcgtgt agcgcaactt gcagaaaaat
    22141 tgcatcagaa agcgcaggcc ggtgaacgaa tgccgtcatg tattaacatc atcagtggtc
    22201 ccagttcaac ggcggacatt gagcttatca aagtcgtcgg ggttcatggt ccggtgaaag
    22261 cggtgtatct gattattgag gattgctgag agagatatgt agtctggaca taaacctgaa
    22321 ggcggtatac gaggttgtga atagcgttaa ggacaacctg acttaacccc gttccgtcat
    22381 ggttatgctg ctcttctgta aatatcctga cattaataat gccaggatat ttacagttaa
    22441 aaagacagga atccattcct gaagacgggc tcccttcccg gtcactgtca ctatagtttt
    22501 atacaggcac tctctgtcag aatgctgttt attactgccc agagttttgt tggtattcat
    22561 ctaccatttt t
//
LOCUS       DAPOXO010000081        22350 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPOXO010000081 DAPOXO010000000
VERSION     DAPOXO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22350
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.081"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            159..374
                     /gene="bdm"
                     /locus_tag="ROH59_003797"
     CDS             159..374
                     /gene="bdm"
                     /locus_tag="ROH59_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310112.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HDX4806229.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAEHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            476..613
                     /gene="sra"
                     /locus_tag="ROH59_003798"
     CDS             476..613
                     /gene="sra"
                     /locus_tag="ROH59_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HDX4806230.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            769..2466
                     /gene="maeA"
                     /locus_tag="ROH59_003799"
     CDS             769..2466
                     /gene="maeA"
                     /locus_tag="ROH59_003799"
                     /EC_number="1.1.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDX4806231.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLV
                     LPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWHAEYRDYRRTSI"
     gene            2600..3610
                     /gene="adhP"
                     /locus_tag="ROH59_003800"
     CDS             2600..3610
                     /gene="adhP"
                     /locus_tag="ROH59_003800"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HDX4806232.1"
                     /translation="MKAAVVTKDHHVDVTDKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATKMGADLAINSRTEDA
                     AKIVQEKAGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLEDINTIFTEMEEGKIRGRMVIDF
                     RR"
     gene            3796..4073
                     /locus_tag="ROH59_003801"
                     /pseudo
     CDS             3796..4073
                     /locus_tag="ROH59_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011039853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            4073..4357
                     /locus_tag="ROH59_003802"
     CDS             4073..4357
                     /locus_tag="ROH59_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDX4806233.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
     gene            complement(4407..5060)
                     /gene="fdnI"
                     /locus_tag="ROH59_003803"
     CDS             complement(4407..5060)
                     /gene="fdnI"
                     /locus_tag="ROH59_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HDX4806234.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPIQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI"
     gene            complement(5053..5937)
                     /gene="fdnH"
                     /locus_tag="ROH59_003804"
     CDS             complement(5053..5937)
                     /gene="fdnH"
                     /locus_tag="ROH59_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase N subunit beta"
                     /protein_id="HDX4806235.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDEEEGNHE"
     gene            complement(5950..8997)
                     /gene="fdnG"
                     /locus_tag="ROH59_003805"
     CDS             complement(5950..8997)
                     /gene="fdnG"
                     /locus_tag="ROH59_003805"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(8410..8412),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDX4806236.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDDTLTHPRCVWNLLKAHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQAEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGIANGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            9229..10110
                     /gene="yddG"
                     /locus_tag="ROH59_003806"
     CDS             9229..10110
                     /gene="yddG"
                     /locus_tag="ROH59_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HDX4806237.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAVYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
     gene            10383..11771
                     /gene="narU"
                     /locus_tag="ROH59_003807"
     CDS             10383..11771
                     /gene="narU"
                     /locus_tag="ROH59_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter NarU"
                     /protein_id="HDX4806238.1"
                     /translation="MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLL
                     LAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRW
                     TVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK
                     QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWV
                     PLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLF
                     LTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQA
                     QREAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLT
                     WLVYGRRKFSQK"
     gene            11866..15606
                     /gene="narZ"
                     /locus_tag="ROH59_003808"
     CDS             11866..15606
                     /gene="narZ"
                     /locus_tag="ROH59_003808"
                     /EC_number="1.7.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase Z subunit alpha"
                     /protein_id="HDX4806239.1"
                     /translation="MSKLLDRFRYFKQKGEIFADGHGQVMHSNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIR
                     SNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFY
                     DWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRY
                     SDMPMLVMLEPRDDGSYVPGRMVRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSI
                     GFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPV
                     LVRQLPVKNLTLADGSTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGE
                     QITGVPRQYIETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGC
                     VGQSGGGWAHYVGQEKLRPQTGWLPLAFAFDWNRPPRQMNSTSFFYNHSSQWRYEKVT
                     AQELLSPLADASKYSGHLIDFNVRAERMGWLPSAPQLGRNPLSLKAEADKAGLSPTEF
                     TAQALKSGDLRMACEQPDSGSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQG
                     EELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMN
                     TSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVCVGHLGKETDVVLQPLLHDS
                     PAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGK
                     GISWNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQ
                     ALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVH
                     ELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNF
                     LTPHQKWGIHSTYSENLLMLTLSRGGPIVWISETDARELTIVDNDWVEVFNANGALTA
                     RAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQL
                     AWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK"
     gene            15603..17147
                     /gene="narH"
                     /locus_tag="ROH59_003809"
     CDS             15603..17147
                     /gene="narH"
                     /locus_tag="ROH59_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDX4806240.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQDEWQGGWVRDVNGKIRPRLGSKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            17147..17842
                     /gene="narW"
                     /locus_tag="ROH59_003810"
     CDS             17147..17842
                     /gene="narW"
                     /locus_tag="ROH59_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDX4806241.1"
                     /translation="MQILKVLGLLMEYPDELLWECKDDALALIRRDAPMLTDFALDLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLNCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILTLLGGRLKQREAPWYALFDALLQLAGS
                     PLSSDSVTKQIRSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            17839..18519
                     /gene="narI"
                     /locus_tag="ROH59_003811"
     CDS             17839..18519
                     /gene="narI"
                     /locus_tag="ROH59_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDX4806242.1"
                     /translation="MIQYLNVFFYDIYPYLCGTVFILGSWLRYDYGQYTWRAASSQML
                     DKRGMVLWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAVKQQMAMILGGICGVLT
                     LIGGAGLLVRRLTNPRIRATSSGADILILAILLIQCILGLTTIPFSAQHPDGSEMMKL
                     VGWAQSIVTFQGGASTHLDGVAFIFRVHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            18599..19492
                     /locus_tag="ROH59_003812"
     CDS             18599..19492
                     /locus_tag="ROH59_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HDX4806243.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRSKVLGLGNCTVWQTSLAGK
                     HRVTIEKQNDDYRISLEQGTPGFEPPLTGETRAAIINALHLTEDDILPGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLAALTAISKQIGCNGFFPFQIRPGKSETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGNVLRVKGHQGRALGRDGVIDVTVTIRDNQP
                     EKVTISGTAVILFHAEWAIDF"
     gene            complement(19588..20433)
                     /gene="nhoA"
                     /locus_tag="ROH59_003813"
     CDS             complement(19588..20433)
                     /gene="nhoA"
                     /locus_tag="ROH59_003813"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HDX4806244.1"
                     /translation="MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVL
                     QFNHHQHWQSMYRFDLCEQQQSDYVIGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTHYENGHAVEQRNLPDVASLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            20608..21177
                     /locus_tag="ROH59_003814"
     CDS             20608..21177
                     /locus_tag="ROH59_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDX4806245.1"
                     /translation="MSQFIPVELHHASCLLNHGPTVMITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIEGNGKFGIVIPGVAATNWTWAVGSVSGREEDKFNCY
                     GIPVVRGPVLGLPLVEEKCLAWMECRLLPATSAQEKYDTLFGEVVSAAADARVFVEGR
                     WQFDDDKLNTLHHLGAGMFVTSGKRVTAG"
     gene            complement(21248..>22350)
                     /locus_tag="ROH59_003815"
     CDS             complement(21248..>22350)
                     /locus_tag="ROH59_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HDX4806246.1"
                     /translation="IPDYRQAWKVEHKLSDILLLTICAVISGAEGWEDIEDFGETHLD
                     FLKQYGDFDNGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDDKDVIAIDGKTLR
                     HSYDKSRRKGAIHVISAFSTMHSLVIGQIRTDEKSNEITPIPELLNMLDIKGKIITTD
                     AMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNPEHDSYAISEKSH
                     GREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSA
                     DLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTN
                     DKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS"
BASE COUNT         5324 a         5829 c         5694 g         5503 t
ORIGIN      
        1 caataataat acctatcaat atcatggagt taaaatataa aatcatcaac caggactaat
       61 cttaacaacg aagcagcaaa tatttgccat gctgaatgtg ctttataaat ctgcgatccg
      121 tagcagacac cataaataca cagacacgga gaatcactat gtttacttat tatcaggcag
      181 aaaattcaac agcagaaccc gctctggtta atgccattga gcaaggcctt cgggcagagc
      241 acggtgttgt cactgaagat gacattctca tggagctgac caaatgggtg gaagcttctg
      301 ataacgacat cctcagtgat atctaccagc aaacgatcaa ttatgtggtc agtggtcagc
      361 accctacgct ttaaggtgct atgcttgatc ggcaacctaa tttaggggtt tagcacgtgt
      421 ttcttcgcta cggcgatgtt gtccttaaaa ctagcaacag gattgaggag ttaaaatgaa
      481 atcgaaccgt caggcacgtc atattcttgg actggaccat aaaatttcta accagcgcaa
      541 aatagttacc gaaggtgaca aatccagcgt ggtaaataat cccaccggca gaaaacgccc
      601 cgctgaaaag taattcataa ccatcagtcc tcaatgacga ttaaacacca ttgcctgcgc
      661 aatggtgttt ttgtttttat ctgctttata cttggtgccg acgccctggc ggtaatgcaa
      721 agacgataaa agcccccagg gatggatatt caaaaaagag tgagtgacat ggaaccaaaa
      781 acaaaaaaac agcgttcgct ttatatccct tacgctggcc ctgtattgct ggaatttccg
      841 ttgttgaata aaggcagcgc cttcagcatg gaagaacgcc gtaacttcaa cctgctgggg
      901 ttactgccgg aagtggtcga aaccatcgaa gaacaagcgg aacgagcatg gatccagtat
      961 cagggattca aaaccgaaat cgacaaacac atctacctgc gtaacatcca ggacactaac
     1021 gaaaccctct tctaccgtct ggtaaacaat catcttgatg agatgatgcc agtcatttac
     1081 accccaaccg tcggcgcagc ctgtgagcgt ttttctgaga tctaccgccg ttcacgcggt
     1141 gtgtttatct cttaccagaa ccgccacaat atggacgata ttctgcaaaa cgtaccaaac
     1201 cataatatca aagtgattgt ggtgactgac ggcgaacgta ttctggggct tggtgaccag
     1261 ggcatcggcg ggatgggcat tccgatcggt aaactgtcgc tctataccgc ctgtggcggc
     1321 atcagtccgg cctataccct tccggtggtg ctggatgtcg gcaccaacaa ccaacagctg
     1381 cttaacgatc cgctgtatat gggctggcgt aatccgcgta tcactgacga tgaatactat
     1441 gaattcgttg atgaatttat ccaggctgtg aaacaacgct ggccggacgt actgttgcag
     1501 tttgaagact tcgcacaaaa aaatgcgatg ccgttactta accgctatcg caatgaaatt
     1561 tgttctttta acgatgacat tcagggcacc gcggcggtaa cagtcggcac actgatcgca
     1621 gccagccgcg cggcaggcgg tcagttaagc gagaaaaaaa tcgtcttcct tggcgcaggt
     1681 tcagcgggat gcggcattgc cgaaatgatc atcgcccaga cccagcgcga aggattaagc
     1741 gaggaagcgg cgcggcagaa agtctttatg gtcgatcgct ttggcctgct gaccgacaag
     1801 atgccgaacc tgctgccttt ccagaccaaa ctggtgcaga agcgcgaaaa tctcagtgac
     1861 tgggataccg acagcgatgt gttgtcactg ctggatgtgg tgcgtaatgt aaaaccagat
     1921 attctgattg gcgtctcagg acagaccggg ctgtttacgg aagagatcat ccgtgagatg
     1981 cataaacact gtccgcgtcc gatcgtgatg ccgctgtcta acccgacttc acgcgtggaa
     2041 gccacaccgc aggacattat cgcctggact gaaggtaacg cgctggtcgc cactggcagt
     2101 ccgtttaatc cagtggtatg gaaagataaa atctacccta tcgcccagtg taacaacgcc
     2161 tttattttcc cgggcatcgg gctgggtgtt attgcttccg gcgcgtcacg tatcaccgat
     2221 gagatgctga tgtcggcaag tgaaacactt gctcagtatt cgccgctggt cctgaacggc
     2281 gaaggtctgg tactaccgga actgaaagat attcagaaag tctcccgcgc aattgccttt
     2341 gcggttggca aaatggcgca gcagcaaggc gtggcggtga aaacgtctgc cgaagctctg
     2401 caacaggcca ttgatgataa tttctggcac gccgaatacc gcgactaccg ccgtacctcc
     2461 atctaagcct gcgcccggta gtgagggcta ccgggcaatt ttcctctccc tttttcagat
     2521 ctcatccata ctgggtagtg gcgaataaat ctcatttgcc tcacctgcta tgcagaacat
     2581 catccgaaaa ggaggaacta tgaaggctgc agttgttacg aaggatcatc atgttgacgt
     2641 tacggataaa acactgcgct cactgaaaca tggcgaagcc ctgctgaaaa tggagtgttg
     2701 tggtgtatgt cataccgatc ttcatgttaa gaatggcgat tttggtgaca aaaccggcgt
     2761 gattctggga cacgaaggta ttggtgtggt ggcagaagtt ggccctggtg ttacttcatt
     2821 aaaaccaggc gatcgtgcca gcgtggcgtg gttctatgaa ggatgcggtc attgcgaata
     2881 ctgtaacagt ggtaacgaaa cgctctgccg ttcagttaaa aatgccggat acagcgttga
     2941 tggcgggatg gcggaagagt gcatcgtggt cgccgattac gcggtaaaag tgccagatgg
     3001 tctggactcg gcggcggcca gcagcattac ctgtgcgggg gtcactacct acaaagccgt
     3061 taagctgtca aaaattcgtc caggacagtg gattgctatc tacggtcttg gcggtctggg
     3121 taacctcgcc ctgcaatacg cgaagaatgt ctttaacgcc aaagtgatcg ccattgatgt
     3181 caatgatgaa cagttaaaac tggcaaccaa aatgggtgca gatttagcga ttaactcacg
     3241 caccgaagac gccgccaaaa ttgtgcagga gaaagccggt ggcgctcacg cagcggtggt
     3301 gacagcggta gctaaagctg cgtttaactc ggcggtggat gctgtccgtg caggtggtcg
     3361 tgtcgtggct gtcggtctgc cgccggagtc tatgagcctg gacatcccac ggctggtgct
     3421 ggatggtatt gaagtggtcg gttcgctggt cggcacgcgt caggatctaa ccgaagcctt
     3481 ccagtttgcc gccgaaggca aagtggtgcc gaaagtcgcc ctgcgtccgt tagaggacat
     3541 caacaccatc tttaccgaga tggaagaagg caaaatccgt ggccgtatgg tgattgattt
     3601 ccgtcgctaa gaggtctttg ctgcgactgc catgttcggg tcgcagcctg tttcgcgaga
     3661 cgctttccgt aatttcactc ttcttctttt cctcccccat atttcccctc acaattcgcg
     3721 aaaacgtagc gaaatttgtt gcgctgcacg gaacaatagt gatagtgttc cttttgaggg
     3781 aacaaggatg aagagatgat aatgaatttc agacacaagg gattgcgtga cttgtttctt
     3841 ctcggcaaaa cctccggcgt tataccgacg caagtcaaac gattacgcca ccactcgctg
     3901 tgattgatgc agcatgctgt cttgctgata tcgatatgcc cggttaccga ctacatccgt
     3961 taagcggcga tcgcgatgga atttgggcga tatctgtctc gggcaactgg cgaatcacat
     4021 ttgaattcgt caatggcgat gcatacatac tggattacga ggactatcac tgatgaaaat
     4081 ggccaatcat ccccgcccgg gggacattat tcaggaatca ctggacgaac ttaatgtcag
     4141 cctgcgcgag tttgccagag caatggaaat tgcgccctca acggcaagcc gattgctgac
     4201 cggaaaagca gctttgacgc cagaaatggc aataaaactt tccgtggtga tcggcagttc
     4261 gccgcaaatg tggctgaatc tgcaaaatgc ctggagtctg gcagaggcgg aaaaaacggt
     4321 ggatgtgtcg cgactgcgcc gtctggttac gcaataaaaa atggcgcttc ttaaagcgcc
     4381 attttcagct taaagttcaa aagagattat atcccttctt cactctcttt tttcgcttct
     4441 gccttctcga tttcacgata ccagcgcgga tggtgtttct tcgcccagcg acggctcacc
     4501 ttcccttcga tcatcccttt aatcgatcct ttcacccaga atgccatata catatggatc
     4561 aggatggcgt ggatcaggat gatacccgca gccgcatgga tcagcaggct ataacggaca
     4621 acctgtatcg ggaagtactg cgcaaagtac ggacgccaga taatcactcc ggtcaccagc
     4681 agcacgaaaa tcatgctcat gattgaccag aacatcatct tttgcccggc gttgtactta
     4741 ccgacatccg ccactttgtg ctcattgcct tttaatactt cgacaatgtt caacagccac
     4801 ggaatatctt tcttatccgg gatgttgtga tgcacaaaac gcacaaacat aaacatcagc
     4861 gcgacgaaaa tcgcaatgcc gaagaacggg tgcaaaatgc gtcccatctg cggcgtaccg
     4921 aaggtttgcg tcagccattg cagcgtcggg aagaagaacg aaatcccgga cagcgccacc
     4981 aggaagaagc aaatcaccac ggtccagtga caggcgcgat caataaattt ggtgcgcaca
     5041 atcattttcg acttactcat gatttccctc ctcctcatcg tccacttcct tattcgggcc
     5101 aataccgatg tagtggaaaa tcaacccggc aaaagtggca ataaagccag ccgctgccag
     5161 cggtttcaac gcgcctttcc acaggcttac cgaggtatcg atcttcggat ctttcggcag
     5221 accatgatac agctccggct gatcggcgtg atgcagcacg tacataacgt gcgtaccacc
     5281 gaccccttcc gggttgtaga cgccagcatg ttcgtaacca cgcgctttca gtttcgccac
     5341 gcgctgttcc gccagctcca gcatctcctt cttggtgccg aagtggatag ccccggtcgg
     5401 acaggttttc acacaagccg gttcctggcc gacgctgacg cgatcgacac agagcgtgca
     5461 tttatatacc cggttatcct ctttgttgag gcgcggaata ttaaacggac acccggcaat
     5521 gcagtaacca cagccgatgc agttttccga ctggaaatcg acaatcccgt tagcgtactg
     5581 aatgattgca ccagcagacg ggcatgcctt caggcagccc ggatcttcac agtgcataca
     5641 gccgtcttta cggatcagcc actccagctt gccgttctgt tcggtttcgc taaagcgcat
     5701 caccgtccag gacttggcgc tcagatcggc ggggttatcg taaaccccga cgcagtgccc
     5761 cacttcatca cggatgtcgt tccactccga acacgccacc tgacaggctt tacagccgat
     5821 acaagtggaa acgtcgataa gtttcgcgac ttctgctttg taatcacgca cctgagaagg
     5881 cggcgtgatg gagttagttg cggacctttt gataatgtcc tgcgtttcca tagccatctg
     5941 ttcgccccct tacgccttct cgatgtttac taagaacgct ttatattccg gcgtttgcga
     6001 gtttgcatca ccgacattcg gcgtcagagt gttagcgata taacctttac gcgcgacacc
     6061 ttcaaagccc cagtggattg gaatacccac cgtttcaacc tgctgaccgt ttacattcag
     6121 cggtttcaga cggcgcgtta ccacagccac cgcgcggata aagccacgct tgctggagac
     6181 agtgacacga tcgccattgg caatgccttt cgccgccgcc agcgtttcgc tgatttccac
     6241 aaactgttcc ggctgagcaa ttgcgttgag caatgcgtgc ttggtccagg tgtggaagtg
     6301 ctccgtcaga cgataggtcg tacccacata cgggaactgc tcttttttac ccatccgcag
     6361 cgcgtcttgt tcatacagac gaacaaccgg gttagacacc acgttcggat gcaacgggtt
     6421 agtgcccagc ggcgtttcaa ttggctcgta gtgttccggg aacggacctt ccgccatttt
     6481 gttgatggca aacaggcgtc ccatcccttc cggttgcatg ataaacggcc cggttggcgt
     6541 acccggcgcg gcattgccga agtccggaat atcgttaccc gtccacttgc taccgttcca
     6601 ctggatcagc atccgtttcg gatcccacgg tttaccgttg atatccgccg aagcacggtt
     6661 gtagagtacg cgacggttga gcggccacgc ccaggcccat cccagcgtat tccccagacc
     6721 ggacgggtcg gagttatcgc ggttagccat ctggttgccc tgctcggtcc agctaccggt
     6781 gtagatccag caagaagatg cggttgtacc gtcatcacgc agatgtgcaa agctactcag
     6841 caactgacct ttcttcgcaa tcagcacgcc attagcgtca tagagatctt ccagcgcata
     6901 gccgttattc tctttcgcca cttcatcaga ctgcggttcg tgcggctgct tgtagttcca
     6961 gctcatcttc atcagcggtt ctacgccttt accaccttcg gcctggtaca gctcgcgcag
     7021 atgatggtag atacccgcca gaatttcgcc gtcgttacgt gcttcgcccg gcgcgtcctg
     7081 acctttccag tgccactgca accagcgacc ggagttagcg atagaaccat cttcttcagc
     7141 aaagcaggtc gaaggcagac ggaatacttc agtctgaata gatgccggat cgacatcgtt
     7201 cgactcgccg tggttctgcc agaaggtaga ggtttcagtc accagcggat cgataaccac
     7261 catgtacttc agcttgctca ggcagctcac cactttgttt ttgtccggga aggacgcaac
     7321 cgggttaaag ccctggcaga aataaccggt gactttacct tcatccatca tgttgaaata
     7381 cttgatgacg tcgtaggtct ggtcccactt cggcagccag tcgtagcccc agttgttctc
     7441 tttctgcgcg gcatcgccgt agaaagattt catcaggcta acgaaaaact tcggatagtt
     7501 gctccagtag ttcacctgat cagccagcgt cgctttcggc gtgttcgctt ccagatacga
     7561 ctgcaaatca acctgttttt ctgacggcag cgtcagataa cctggcaggc tggtagagag
     7621 caggcctaag tcagtcaggc cctgaatgtt ggagtgacca cgcaatgcgt tcacgccgcc
     7681 accggccata cccatgttac cgagcagcaa ctggatcatc gccatcgtac ggatgttctg
     7741 cgcacccacg gtgtgctgcg tccagcccag cgcgtacagg aaggtggttg tgcgatccgg
     7801 tgcgctggtg gaggccagca cttcacacac tttcaggaag tcggcttttg gcgtaccgca
     7861 aatgttttct actacgtccg gcgtgtagcg ggaaacgtgc gctttcagca gattccatac
     7921 acagcgcgga tgagtcagcg tgtcatcgcg tttcgcatag ccgttttcat cgaactgata
     7981 gttccaggac gacttatcgt attgacgttt ttcagcgtcg tagccgctga acagaccgtc
     8041 ttcgaaagca aaatcatcac gcaccagcag gctggcgttg gtgtaatgct taacgtattc
     8101 ggcgttgatt ttgttgtttt cgatcaggta gcgcaaaacg ccagacagga acgtaatgtc
     8161 cgtaccggaa cgaataggtg cgtaaatatc cgccacagaa gcggtacgcg taaaacgggg
     8221 atcgacaacg atcaaggttg catcgttgtt gtttttcgct tccatcgccc agcggaaacc
     8281 gacgggatgc gcttcagcag cgttaccgcc catcaccatt acgacgttag cgtttttgat
     8341 atccacccag tggttggtca tcgcaccgcg accaaatgtt ggagcaagac ttgctaccgt
     8401 tggtccgtgt cagacgcgcg cctggttgtc taccgccagc atcccgaggg agcgggcaaa
     8461 tttttgagtc agcatcccgg tttcgttgct ggcaccggaa gcacacagca taccggtaga
     8521 aagccaacgg tttaccgtta cgccctgctc gttcttttca ataaagttag cgtcacggtc
     8581 ggctttcatc agcttcgcaa tacgggagaa tgcttcttcc cagctaatgc gctgccattt
     8641 gtcagaacct ggcgcacgat attccgggta gcgcagacgg ttttcgctgt tgacataatc
     8701 cagcaaaccg gcccctttcg ggcacagcgc accacgactt accggatgat ccgggtcacc
     8761 ttcaatgtga taaatcgctt ctctggcgtt tttcgcgcca tcacccaggc tatacatcaa
     8821 tagcccgcaa cctacggaac agtatgtgca ggtgttacgg atctctttcg cgcgtaataa
     8881 tttgtagttt cgcgcctgag ccagtgcttg cttcggggca aagcccaatg ctgctactgt
     8941 tgttcccgcc ataccgcccg cgcagatttt aaaaaattgt ctgcgactga cgtccattgc
     9001 tttcctcttt tttcaggggt attactgcgc gaggaaacta acagtaaaat tctgaatctt
     9061 tttgcgcgaa atcaaaaaga acacgtgttt gccacaaaat aatccgcctg cgcaaattga
     9121 cctacctcaa tagcggtaga aaaacgcacc actgcctgac aggccagtta aaaaaatgct
     9181 ataaaattca gcttaatttt taacggcaag agagacaaaa cagcgagcat gacacgtcaa
     9241 aaagcaacgc tcatagggct aatagcgatc gtcctgtgga gcacgatggt aggattgatt
     9301 cgcggtgtca gtgagggact cggcccggtc ggcggcgcag ctgctatcta ttcattaagc
     9361 gggctgctgt taatcttcac ggttggattt ccgcgtattc ggcagatccc gaaaggctat
     9421 ttactcgccg ggagtctgtt attcgtcagc tatgaaatct gtctggcgct ttccttaggg
     9481 tatgcggcga cccgtcatca ggcgattgaa gtggggatgg tgaactatct atggcccagc
     9541 ctgacaattc tctttgccat tctgtttaat ggtcagaaaa ccaactggct gattgtacca
     9601 ggattattat tagccctggt cggcgtctgc tgggtgttag gcggtgacaa tgggttacat
     9661 tatgatgaaa ttatcaataa tatcaccacc agcccattga gttatttcct ggcgttcatt
     9721 ggggcgttta tctgggcagt ctactgcaca gtaacgaata aatacgcacg cggatttaac
     9781 ggaattaccg tttttgtcct gctaacggga gcaagtctgt gggtttacta ttttcttacg
     9841 ccacaaccag aaatggtatt tagcacgccc gtcatgatta aactcatctc tgcggcattt
     9901 accttaggat ttgcttatgc tgcatggaat gtcggtatat tacatggcaa cgtcaccata
     9961 atggcggtag gttcgtattt tacgcccgtc ctttcctcag cgcttgcagc cgtgctgctc
    10021 agcgccccgc tgtcgttctc gttctggcaa ggcgcgctaa tggtctgcgg cggttccctg
    10081 ctctgctggc tggcgacacg tcgtggctaa aataattgtc gggtctacgg cccggcagtt
    10141 aatcagataa attctgacaa tattaaaaaa taaatttcaa ataccagaaa gtcattttag
    10201 ttacatttag taacacatat ctgtctgttt aatccacatt ctgcccccgc agttacgctt
    10261 tcttatctat tcttctaatc agcacttcac ctgattcatc cttaattcta ataactggct
    10321 attgcgcctt acctcctgtt ttgtcttttt ttcattacca atgtgtgcat gtgaggaaca
    10381 atatggcact gcaaaatgag aaaaatagtc gttatctttt acgcgactgg aaaccagaaa
    10441 atccggcctt ctgggaaaat aaaggaaagc atattgcacg aagaaacctc tggatatcag
    10501 tcagttgtct acttcttgcc ttctgtgtct ggatgctatt tagcgcagtt actgttaatc
    10561 tcaataaaat cggttttaat tttactaccg atcaactctt tttattaacc gcattaccct
    10621 ccgtttctgg cgcattattg cgtgtcccct actcctttat ggtgcctata ttcggtggac
    10681 gccgatggac ggtttttagt actgcaatcc tgattattcc ttgcgtctgg ctcggaattg
    10741 ccgtgcagaa tccgaatact ccttttggga tatttatcgt tatcgctttg ctatgcggtt
    10801 ttgcaggtgc gaactttgct tcgagcatgg gcaatatcag tttcttcttt ccaaaagcca
    10861 aacaagggag cgctcttggg attaatggcg gattaggaaa cttaggtgta agtgtaatgc
    10921 agctggttgc accgctggtc atttttgtcc ccgtatttgc ctttctcggc gtcaatggcg
    10981 taccgcaggc cgacggttcg gtgatgtcgc tggcgaatgc cgcatggatt tgggtgccat
    11041 tactggcgat tgccacgatc gccgcctggt cagggatgaa tgatatcgcc agttcacgcg
    11101 cctcaattgc cgaccagctc cctgtcttac aacgcctgca tctctggctg ctgagcctgc
    11161 tttaccttgc caccttcggt tcgtttatcg gtttttctgc gggttttgcc atgctggcaa
    11221 aaacccagtt cccggatgtg aatattctgc gcctggcgtt ctttggccca tttatcggtg
    11281 ccatcgcgcg atcggttggt ggtgctattt ccgataaatt cggcggcgtg cgggtgacgt
    11341 tgatcaactt catttttatg gcgattttca gcgccctgct gttccttacc ttaccgggca
    11401 caggctccgg taatttcatc gcattttacg ccgtatttat ggggctgttt ctgaccgcgg
    11461 gtctgggaag tggttctact ttccagatga tcgccgtcat ctttcgccag ataacaattt
    11521 atcgggtgaa gatgaaaggc ggtagtgatg agcaagctca aagagaagcc gtcaccgaaa
    11581 cggcagccgc tctgggcttt atctcagcca ttggcgcagt gggcggcttt tttattccgc
    11641 aggcgtttgg catgtcgctc aatatgaccg gctctccggt gggcgcgatg aaagtgtttt
    11701 taatcttcta catcgtttgt gtgctactga cctggctggt ttatggtcgg cggaagttca
    11761 gccaaaaata agagatcgat gcctgacacg tcttatcagg ctacaaccgt gtcgcatccg
    11821 acaaggcatc agatcccaat tcattcctgg agcaggagtt atgtcatgag taaacttttg
    11881 gatcgctttc gctacttcaa acaaaagggc gaaatctttg ccgatggtca cggacaggtg
    11941 atgcatagca accgcgactg ggaggacagc tatcgccagc gttggcagtt cgacaaaatc
    12001 gtgcgttcca cccacggtgt taactgtaca ggctcctgta gctggaaaat ctacgttaaa
    12061 aatggtctgg tgacctggga aatccaacag accgattacc cgcgcactcg ccctgacctg
    12121 ccgaatcacg aacctcgcgg ctgcccgcgt ggcgcaagtt actcctggta tctctacagc
    12181 gcgaaccgcc tgaaataccc gctcattcgt aaacgactga ttgaactgtg gcgcgaagcc
    12241 ctcaagcaac acagcgatcc ggtactggcg tgggcatcga ttatgaacga tccgcaaaag
    12301 tgcctgagct acaaacaagt gcgtggacgc ggtggtttta tccgctccaa ctggcaggag
    12361 ctaaatcagc tgattgccgc cgctaacgtc tggaccatca aaacttacgg cccggatcgc
    12421 gttgccggtt tctcgccgat tccggcgatg tcgatggttt cttacgctgc cggaacacgc
    12481 tatctgtcgc tgttaggtgg cacctgttta agcttctacg actggtattg cgacctgccg
    12541 cccgcctcgc cgatgacctg gggcgagcaa accgacgtac cggaatctgc cgactggtat
    12601 aactccagtt acatcatcgc ctgggggtct aacgtaccgc agacacgtac gccggacgcc
    12661 catttcttta ccgaagtacg ctacaaaggc actaaaacca tcgccattac ccctgactac
    12721 tctgaagtgg ccaaattgtg cgaccagtgg ctggcaccga aacaaggcac tgatagtgcc
    12781 ctggcaatgg caatgggcca tgtcatttta aaagagtttc atctcgataa tcccagcgat
    12841 tattttatca actactgccg ccgctacagc gacatgccga tgctggtaat gctggaacct
    12901 cgcgacgacg gcagctacgt tcccgggcgc atggtccgcg catctgacct ggtggatgga
    12961 ctgggcgaaa gcaataatcc gcagtggaaa accgtggcag ttaataccgc aggtgaattg
    13021 gtagtgccga acggttcgat tggttttcgt tggggagaaa aaggcaaatg gaacctggaa
    13081 tccattgccg ccggtacgga aaccgaattg tcgttaaccc tgctcggtca acatgacgcc
    13141 gttgcaggcg tggccttccc ctactttgga ggcattgaaa atccgcattt tcgcagcgta
    13201 aaacacaatc ctgtcctggt gcgccaattg cccgttaaaa atctgacatt agccgatggt
    13261 agcacctgtc cggtggtcag cgtttatgat ctggtactgg caaattacgg cctcgatcgc
    13321 gggctggaag atgaaaacag cgcgaaagat tacgctgaaa tcaaacctta cacccctgcc
    13381 tggggcgagc aaattaccgg cgtaccgcgc cagtatattg aaaccatcgc ccgtgaattt
    13441 gccgataccg ctcataaaac gcatgggcgc tcgatgatta ttctcggcgc aggtgttaac
    13501 cactggtatc acatggacat gaactaccgc gggatgatca atatgctgat cttctgcggt
    13561 tgtgtcgggc aaagcggcgg cggctgggcg cactatgtcg gtcaggaaaa actgcgccca
    13621 caaaccggct ggttgccgct ggcctttgcg ttcgactgga accgtccacc gcgccagatg
    13681 aacagcacct cgtttttcta caatcactcc agccagtggc gctatgaaaa agtcaccgcg
    13741 caggaattgc tctcaccgct cgccgatgcc agtaaataca gcggtcacct gattgatttc
    13801 aacgttcgcg ccgaacgtat gggctggctc ccttctgcgc cgcagctggg gcgtaacccg
    13861 ctctccctga aagctgaagc cgacaaggcc ggattatccc ccacagaatt taccgcccag
    13921 gcgctgaaat cgggcgattt acgtatggcc tgcgaacaac cagatagcgg cagcaatcat
    13981 ccgcgtaatt tgtttgtctg gcgttctaac ctgcttggct cctccggcaa aggccacgag
    14041 tatatgcaga agtatctgct ggggaccgaa agcgggattc agggagagga actcggtgcc
    14101 agcgacggga tcaaaccaga agaagtcgag tggcaaactg cggcgattga aggcaagctc
    14161 gacctgctgg tgacgctcga tttccgcatg tccagtacct gcctgttctc cgatatcgtt
    14221 ctgcccaccg ccacctggta cgaaaaagac gatatgaata cctcggatat gcatccgttt
    14281 attcatccgc tttctgcggc ggtcgatccg gcgtgggaat cacgcagcga ctgggaaatc
    14341 tacaaaggta tcgctaaagc cttttcgcaa gtgtgcgtgg ggcatctcgg caaagaaacc
    14401 gacgtggtat tacaaccact gctgcatgac tccccggcag agctttcaca gccgtgtgaa
    14461 gtgctcgact ggcgcaaagg cgagtgcgat ctgattccag gcaaaaccgc gccgaatatt
    14521 gtggcggtgg agcgcgacta ccctgctacc tatgaacgct ttacctcgct cgggccattg
    14581 atggacaaac ttggcaacgg aggtaaaggg atttcgtgga atacccagga tgaaattgat
    14641 ttcctcggta aactcaatta caccaagcgt gatggcccgg cacaggggcg tccgctgatt
    14701 gataccgcga ttgatgcctc agaagtgatt ctggcgctgg caccggaaac caacggccat
    14761 gttgcagtca aagcgtggca agcgctgggc gagatcaccg gacgcgaaca tacccatctg
    14821 gcgctgcaca aagaggacga gaagattcgc tttcgcgata ttcaggcgca gccgcgtaaa
    14881 attatctcca gccccacatg gtctggtctg gaaagcgatc acgtctccta taatgcggga
    14941 tacaccaacg ttcatgagct aattccgtgg cgcacactgt cgggccgtca acagctttat
    15001 caggatcatc cgtggatgcg tgcctttggt gaaagcctgg tggcttatcg cccgcctatc
    15061 gacacccgca gtgtcagtga aatgcgccaa atcccgccaa acggcttccc ggaaaaagcc
    15121 cttaacttcc tgacaccgca ccagaaatgg ggcattcact caacctacag tgaaaacctg
    15181 ctaatgctga cgctctctcg cggtggaccg attgtctgga tcagcgaaac cgatgcccgt
    15241 gaactgacca ttgtcgataa cgactgggtg gaagtgttta acgccaatgg cgcgctgacg
    15301 gcccgcgcgg tggtcagcca gcgtgtaccg ccgggcatga ccatgatgta tcacgctcag
    15361 gaacgcatta tgaatattcc tggttcggaa gtaaccggca tgcgcggcgg cattcataac
    15421 tcggtcaccc gcgtttgtcc gaaaccaaca catatgattg gcggttacgc gcagctggcc
    15481 tggggcttta actactacgg cactgtcggc tctaaccgcg acgaattcat catgatccgc
    15541 aagatgaaga acgttaactg gctggatgat gaaggtcgcg atcaggttca ggaggcgaaa
    15601 aaatgaaaat acgttcgcaa gtcggcatgg tgcttaacct cgataaatgt atcggctgcc
    15661 atacctgttc ggtgacctgt aaaaacgtct ggaccggtcg cgaaggcatg gagtacgcat
    15721 ggtttaacaa cgtcgaaacc aaaccgggca ttggttatcc gaaaaactgg gaagatcagg
    15781 atgagtggca aggtggctgg gtgcgtgatg tgaatggcaa gatacgcccg cgtctgggca
    15841 gcaagatggg cgtaataacc aaaattttcg ccaacccggt agtgccgcag attgacgatt
    15901 actacgaacc tttcaccttc gactacgaac atttgcatag cgcgccggaa ggcaaacata
    15961 ttcccaccgc ccgtccgcgt tcactgattg acggcaaacg gatggacaaa gtgatctggg
    16021 gcccaaactg ggaagaactg ctgggcggcg aatttgaaaa acgagcccgc gaccgcaact
    16081 tcgaggccat gcaaaaggag atgtacgggc agtttgaaaa caccttcatg atgtacctgc
    16141 cgcgcctgtg cgaacactgc ctcaatccca gctgcgtggc gacctgcccc agcggcgcta
    16201 tctacaaacg cgaagaagac ggcattgtgc tgattgatca ggataaatgc cgtggctggc
    16261 gtttgtgcat tagcggttgt ccgtacaaaa aaatctactt caactggaaa agcggcaagt
    16321 cagaaaaatg tatcttctgt tatccgcgaa ttgagtccgg tcagccaaca gtctgctccg
    16381 aaacctgcgt gggtcgcatc cggtatctgg gcgtgctgct ctacgacgcc gaccgcatcg
    16441 aagaagcagc gagtaccgaa cgagaggtcg atctctatga acgccagtgc gaagtgttcc
    16501 tcgatccgca cgatccctca gtgatcgaag aagccctgaa acaaggtatt ccacaaaacg
    16561 tgattgacgc tgcccagcgt tcgcctgtct acaaaatggc gatggactgg aaactggcgc
    16621 taccgctgca ccctgaatac cgcaccctgc cgatggtctg gtacgttcct ccgctgtcac
    16681 cgattcagtc ctacgctgat gcgggaggtt tgccgaaaag cgaaggcgtg ctgcccgcca
    16741 tcgaaagcct gcgtattccg gtgcaatatc tcgccaatat gttgagtgcc ggtgataccg
    16801 gtccggtact gcgggcgctg aaacggatga tggcgatgcg ccactatatg cgttcacaaa
    16861 ccgtggaagg cgttactgat actcgtgcca tcgacgaagt aggtctgagc gtcgcccagg
    16921 tcgaagagat gtatcgttac ctcgccattg ccaactatga agatcgtttc gtcatcccga
    16981 caagccatcg ggaaatggcg ggcgatgcct tcgcagaacg caacggctgc ggttttacct
    17041 ttggcgacgg ttgccacggt tcggacagca aattcaacct gttcaacagt agccgtatcg
    17101 atgccatcaa catcaccgaa gtgcgcgaca aagcggaggg cgaataatgc agatcctcaa
    17161 agtgctcggc ctgttgatgg agtacccaga cgagttgttg tgggagtgta aggacgacgc
    17221 gctggcgctt atccgccgcg acgcgccgat gctcaccgat tttgcactcg acctgctcaa
    17281 cgccccgctg ctggataaac aggccgaatg gtgtgaagtg tttgaccgcg ggcgcaccac
    17341 gtcgctgctg ctgtttgaac atgttcatgc cgagtcccgc gatcgcggcc aggcaatggt
    17401 ggacctgctg gcggagtatg aaaaggtcgg tctgcaactg aattgtaggg aactgcccga
    17461 ttatctaccg ctgtatctgg agtatttaag cgtacttccg gacgatcagg cgaaagaagg
    17521 attactcaac gttgcgccga tcctcaccct gcttggcgga cgcttaaaac aacgcgaggc
    17581 accgtggtac gcgttatttg acgccctgtt gcaactggca ggaagccctc tgtcaagtga
    17641 cagtgtcaca aaacagattc gcagtgaaga gcgtgacgac acccgccagg cgctggatgc
    17701 ggtgtgggaa gaagaacagg tgaagtttat tgaagataac gccacggcgt gtgacagctc
    17761 gccgcttaat caatatcagc gacgctttag ccaggatgtc gcgccgcagt atgtcgacat
    17821 cagtgcggga ggtgggaaat gattcagtat ctgaacgtct ttttttacga tatctacccg
    17881 tacttgtgtg gcacggtttt tatccttgga agctggctgc gctacgacta cgggcagtac
    17941 acctggcgcg ccgcctccag ccagatgctg gataaacgcg ggatggtgct gtggtcaaac
    18001 ttgttccata tcggcatttt ggggattttc ttcgggcacc tgttcggcat gttaacgcca
    18061 cactggatgt acgcgtggtt tctgccggtg gcggtaaaac agcagatggc gatgatcctc
    18121 ggcggaatat gcggggtatt gacgctgatt ggcggtgcgg ggctactggt gcgtcgttta
    18181 acaaatccgc gtatcagggc gacgtcttct ggtgcggata tcctgatcct cgccattttg
    18241 ttaattcagt gcattctcgg gttaaccacc attccttttt cagcacaaca tccggacggc
    18301 agtgaaatga tgaagctggt gggctgggcg caaagcattg tcactttcca gggcggtgca
    18361 tctacgcatc ttgatggtgt cgcctttata ttccgcgttc atctggtgct tggaatgacc
    18421 atcttcctgc tcttcccgtt cacccgactg gtgcatgtct ggagcgcgcc gtttgagtac
    18481 tttactcgtc ggtatcagat tgtgcgttcg cggcgttaat tctcacgcgg gccggatagc
    18541 ccttcgctct ccggccactt gcaggctatg atagttctcc agccacagga gaacgttaat
    18601 gaaaccgcaa gtgtaccacg tcgatgcttt tacctctcaa ccgtttcgcg gcaattctgc
    18661 cggtgttgtt ttccccgccg ataatctcag tgaagcgcaa atgcagctta tcgcccgcga
    18721 gttaggtcat tcggaaactg cttttctgct gcacagcgac gacagcgatg tgcgcatccg
    18781 ctactttacg ccaacggttg aagtgccaat ttgcggtcac gcgacggtgg ctgcgcacta
    18841 tgtacgttca aaggtattag gtttgggaaa ttgcacggtc tggcaaacgt cgctggcagg
    18901 aaaacatcgt gtgactatcg aaaagcaaaa tgatgattat cgtatttcgc tggaacaagg
    18961 tacgccaggc tttgagccac cactgacagg tgaaacacgt gcagcgatta tcaacgcgct
    19021 tcatctcact gaggacgata ttctgccagg cttgccaatt caggtggcaa caacaggaca
    19081 ctcaaaagtg atgatcccgt tgaaaccaga agtggatatc gacgcccttt cgcctgatct
    19141 tgctgcgttg accgctatca gcaaacagat tggctgcaat ggtttcttcc cgttccagat
    19201 ccgcccaggc aaaagcgaaa ccgacggtcg catgttctcg cctgcgattg gtattgtgga
    19261 agatccggtg accgggaatg ccaatggtcc gatgggcgca tggttagtac atcacaacgt
    19321 attgccccac gatggcaacg tgttgcgtgt taaaggccat caggggcgcg cattggggcg
    19381 tgatggtgta attgatgtga cggtgacaat tcgcgataac caaccggaga aagttaccat
    19441 ttccggcacg gcggtgattc tattccatgc tgaatgggcc attgattttt gatgccgttg
    19501 cctgatgcgc ttcgcttatc aggcctacaa ccggactaat gtaggccgga taaggcattt
    19561 acgccacatc cggcaacctg acataaatta ttttcccgcc tccgggtgcg tatcaaacgc
    19621 cgccatcacc agcgctaact catccacagt aaagccatgt ttcgcatcat ctacgcccag
    19681 accaaactgt tcctgcatca cggcatataa cgacgccaca tctggtagat ttcgctgctc
    19741 aactgcgtgc ccattttcat aatgggtaaa atgaaaattg gtcagcgtta gcttgccacc
    19801 gtccggcaaa tggcgacaca tcagcaaatg atggcgaaaa tgcgactgcg gccagtgcgc
    19861 cgaccagaaa ttgcctatca cataatcgct ttgttgctgc tcgcagagat caaaacggta
    19921 catcgactgc cagtgctgat gatgattaaa ctgcaatacc caatcatcac cctcttgcaa
    19981 caaccgatac tctccgtgtg gcgtggtttg catgatatcc ggcattaaac gaatcggcgc
    20041 ggttagcgtc tgcccaccga aaccgacatc agcaatccat ttttcccctt ccagttccac
    20101 caacagcaaa cgatgggtgc gcggcggtaa tgctggcgga tttgataaca ctacgcgacc
    20161 taacaagctg cgaacgttaa accccagctc gcgtaacacc cgctcaaaca cgccattctg
    20221 ctcaaaacag taaccgccac gacgggctat caccagtttc tcttccagcg attgatcatc
    20281 aagctgtatt tccctcggca gcaaaacgtc gagattttca aacggaatgg tgcaattgtg
    20341 tttcaggtgc aatgcacgca gcgtatcaat attggccgca gcagctccca accagttaat
    20401 acgggcaaaa taatgattca gaatgggcgt catcaggcgt ttcccttagt ggttttctca
    20461 acttataacc tggaatagac gccgcactgg ctattttgtg cgatcgcgga catgcatcac
    20521 gttcgcaaat cgccaatccc gttaatttcg ttacttattg cgttacgagc tacgctttta
    20581 aaacaccctt catagcgagg cgatatcgtg agccaattca ttcccgtcga attacaccat
    20641 gccagctgtc tgttaaatca tggcccaact gtcatgatca ccagtttcga tgagcaatcc
    20701 cagcggcgta acattatggc agcagcctgg tcgatgcccg tagagtttga accgccacgc
    20761 gtggcgattg tggtagataa atcgacatgg accagggagt tgattgaagg taacggtaaa
    20821 tttggcatcg ttatcccggg cgttgcggcg actaactgga cgtgggcggt gggaagtgtg
    20881 tcgggtcgtg aagaagataa gtttaattgc tacggcattc cggtagtgag aggcccggtg
    20941 cttggtttgc cgctggtcga ggaaaaatgt ctggcgtgga tggagtgtcg cctgctacct
    21001 gcgacttccg cgcaagaaaa atacgatacg ctatttggcg aagtggtatc tgcagcggca
    21061 gacgcacgag tatttgtcga aggccgctgg cagtttgatg atgataagct caatacgttg
    21121 catcatttag gtgctggcat gtttgttacc agtggtaagc gagttacggc aggttaagca
    21181 ttacatgctg taaccgggtt tctttatcaa agcctccatt tggggcgcga tttcggccag
    21241 ggcaagatta cgaaagcccg ctccccgcaa ggactgacgc gagatagttt ctgtccatgg
    21301 ctgcttttcg catcttacgt cttaaccctg ccttgaatac cttatcattc gttaaaatat
    21361 taatagcgat gtgccgtatc cctgaaaata attctgcggc gtttcctctt cttattttgc
    21421 agtcgtcttc attcattacc acgtccagac gccagtgcag cttattctcc acgtgccagt
    21481 ggtttcggat tgctgtggcg aacttctctg cggttaaatc agcagaactg atataatatc
    21541 tgaccgtcat ttctggctct ttcttttgtt ctgctattat ggaccgaaag gagactgcca
    21601 cgcataattt cttcagtcct ttccattcga acgtgaaatc aataagttca tcagggacat
    21661 cgcaaacaat atgaagacgg atttcttctc tgccgtgact cttttcacta atggcgtaac
    21721 tgtcatgttc tggattattt aattctttca gtggaaattt ttcctcaaag gctttattaa
    21781 gccgcccctg atttcctttt acagcgaata aataatcacc gccctgtttt tgtatcttct
    21841 ctgcaatatc tttctggcaa cccatcgcat cagttgtgat gatttttcct ttaatatcca
    21901 gcatgttaag aagttcaggg ataggtgtaa tttcattgga tttctcatcc gtcctgatct
    21961 gtccgatgac cagactgtgc attgttgaga acgcactaat gacatgaatc gctcccttgc
    22021 ggcgactctt gtcataagaa tgccggagtg tttttccatc aattgcgatg acgtctttat
    22081 catctgaaga atggcagtca cgcatccagt taataaagca ctcgtgaaat tttgcaggac
    22141 tgatacagga tacaactctg gcaatggtat cgtgaacagg aataccatta tcaaaatcac
    22201 catattgctt caaaaaatcg agatgtgttt ccccaaaatc ctctatatct tcccagcctt
    22261 ctgcacccga aataacggca caaatagtca acagtagaat atccgataat ttatgttcca
    22321 ctttccaggc ttgtctgtaa tcggggataa
//
LOCUS       DAPOXO010000082        21964 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPOXO010000082 DAPOXO010000000
VERSION     DAPOXO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21964
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.082"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(37..2466)
                     /gene="torZ"
                     /locus_tag="ROH59_003816"
     CDS             complement(37..2466)
                     /gene="torZ"
                     /locus_tag="ROH59_003816"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310609.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine N-oxide reductase TorZ"
                     /protein_id="HDX4806247.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRW
                     GAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDHIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKNDNTPKSAAWAAEITGVPEAQ
                     IVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYS
                     NGGNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQ
                     TYPNIKMIWWAGGGNFTHHQDTNRLIKAWQKPEMIVVSECYWTAAAKHADIVLPITTS
                     FERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKPGGKEIYTEGKDE
                     MAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYIRYGDFRADPVK
                     NALGTPSGKIEIYSRTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLH
                     SQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLVRVWNKRGQILTGAVVTDGIK
                     KGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNALK
                     LTAFDQPAIQA"
     gene            complement(2491..3591)
                     /locus_tag="ROH59_003817"
     CDS             complement(2491..3591)
                     /locus_tag="ROH59_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HDX4806248.1"
                     /translation="MRGKKRIGLLFLLIAVVVGGGGLLLAQKALHKTSDTAFCLSCHS
                     MSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDS
                     DDKFEAHRQEMAETVWKELKATDSATCRSCHSFDAMDISSQSESAQKMHNKAQKDGET
                     CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKTSRIGDLATVTPGTD
                     LTVVDVSGKQPIVRLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADE
                     YGNQWRQASLQGALTDSALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIA
                     KGMGARTSMSENELDILTRYFQYNAKDITEKQ"
     gene            complement(3979..4725)
                     /gene="cutC"
                     /locus_tag="ROH59_003818"
     CDS             complement(3979..4725)
                     /gene="cutC"
                     /locus_tag="ROH59_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDX4806249.1"
                     /translation="MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLNTLNNLTELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DAHADEYSRYVVDGAAVAEMKGIIERHQAK"
     gene            complement(4739..5305)
                     /locus_tag="ROH59_003819"
     CDS             complement(4739..5305)
                     /locus_tag="ROH59_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDX4806250.1"
                     /translation="MANWQSIDELQDIASDLPRFTHALDELSRRLGLDITPLTADHIS
                     LRCHQNVTAERWRRGFEQCGELLSENMINGRPICLFKLHEPLQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            5521..7254
                     /gene="argS"
                     /locus_tag="ROH59_003820"
     CDS             5521..7254
                     /gene="argS"
                     /locus_tag="ROH59_003820"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDX4806251.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEINEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            complement(7307..7699)
                     /gene="flhe"
                     /locus_tag="ROH59_003821"
     CDS             complement(7307..7699)
                     /gene="flhe"
                     /locus_tag="ROH59_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HDX4806252.1"
                     /translation="MRALLAILLFPLLVQAAGEGMWQASSVGVTLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPAGLRVRLCSQSRCVELEGQSGTTMAFSGIPAAEPL
                     RFIWEVPGGGRLTPPLKIQRNEVIVNYR"
     gene            complement(7699..9777)
                     /gene="flhA"
                     /locus_tag="ROH59_003822"
     CDS             complement(7699..9777)
                     /gene="flhA"
                     /locus_tag="ROH59_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDX4806253.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NVVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PAEPKPVKMAENNSVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPARYRILMKGVEMGSGDAYPGRWLAINPGTAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(9770..10918)
                     /gene="flhB"
                     /locus_tag="ROH59_003823"
     CDS             complement(9770..10918)
                     /gene="flhB"
                     /locus_tag="ROH59_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HDX4806254.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIINDPNLILGQIILLIREAMLALLPLISGVVLV
                     AIISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRTFSAQTGAELLKAILKTILVGSVTG
                     FFLWYHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(11107..11751)
                     /gene="cheZ"
                     /locus_tag="ROH59_003824"
     CDS             complement(11107..11751)
                     /gene="cheZ"
                     /locus_tag="ROH59_003824"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HDX4806255.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVIDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQGQVDDLLDSLGF"
     gene            complement(11762..12151)
                     /gene="cheY"
                     /locus_tag="ROH59_003825"
     CDS             complement(11762..12151)
                     /gene="cheY"
                     /locus_tag="ROH59_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HDX4806256.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(12166..13215)
                     /gene="cheB"
                     /locus_tag="ROH59_003826"
     CDS             complement(12166..13215)
                     /gene="cheB"
                     /locus_tag="ROH59_003826"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HDX4806257.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELARSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(13218..14078)
                     /gene="cheR"
                     /locus_tag="ROH59_003827"
     CDS             complement(13218..14078)
                     /gene="cheR"
                     /locus_tag="ROH59_003827"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDX4806258.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRALGLADFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLAKQY
                     TVPGPFDAIFCRNVMIYFDQTTQQEILRRFVSLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(14193..14323)
                     /locus_tag="ROH59_003828"
                     /pseudo
     CDS             complement(14193..14323)
                     /locus_tag="ROH59_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310622.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tar ligand binding domain-containing protein"
     gene            complement(14369..16030)
                     /gene="tar"
                     /locus_tag="ROH59_003829"
     CDS             complement(14369..16030)
                     /gene="tar"
                     /locus_tag="ROH59_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HDX4806259.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQSELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYHTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLAAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLAATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF"
     gene            complement(16175..16678)
                     /gene="cheW"
                     /locus_tag="ROH59_003830"
     CDS             complement(16175..16678)
                     /gene="cheW"
                     /locus_tag="ROH59_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDX4806260.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(16699..18663)
                     /gene="cheA"
                     /locus_tag="ROH59_003831"
     CDS             complement(16699..18663)
                     /gene="cheA"
                     /locus_tag="ROH59_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDX4806261.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEA
                     DQITFETVDVSPKISTSPMLKLAAEQAPTGRVEREKTTRSSESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSMQGTGTTIRILLPLT
                     LAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(18668..19594)
                     /gene="motB"
                     /locus_tag="ROH59_003832"
     CDS             complement(18668..19594)
                     /gene="motB"
                     /locus_tag="ROH59_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HDX4806262.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKRPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLNGGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(19591..20478)
                     /gene="motA"
                     /locus_tag="ROH59_003833"
     CDS             complement(19591..20478)
                     /gene="motA"
                     /locus_tag="ROH59_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HDX4806263.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLEFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLASVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(20605..21183)
                     /gene="flhC"
                     /locus_tag="ROH59_003834"
     CDS             complement(20605..21183)
                     /gene="flhC"
                     /locus_tag="ROH59_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HDX4806264.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(21186..21536)
                     /gene="flhD"
                     /locus_tag="ROH59_003835"
     CDS             complement(21186..21536)
                     /gene="flhD"
                     /locus_tag="ROH59_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HDX4806265.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAT
                     TLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLN
                     DVNQPEEALRKKRA"
BASE COUNT         5239 a         6036 c         5307 g         5382 t
ORIGIN      
        1 aaaatttagc gcccgtttcc gggcgctttt tacgtcttat gcctgaatag ctggctgatc
       61 aaacgccgtt aacttcagcg cattgcccgt atatttttcg atatacacca gcgcagagtt
      121 accggcacag gcattcgcca gctgcgagct ggggatatcc gccgttaaca cgttcgcact
      181 accgttttta cacaagccat tttccagatc tggccatgca ccttcatgca cgcataccac
      241 gccttttttg atcccgtcag tcaccaccgc gcctgtcaga atctgaccac gtttgttcca
      301 gacacgcacc agatcgccat tcgcaatacc aaagcgagca gcatcttcgg tgtgaatagt
      361 gattggttca cgatcggcaa ccgcatattt tttacgcagt tccgcatagt taagctgact
      421 gtgtaaacgg tgtgccggat gtgcggtcag aagctgcaac tgcttctcgt cggcggtacc
      481 cttccactca tcaggcgcaa gccaggttgg gtgtgccggg caatccttat agccaaattt
      541 ttccagcgtt ctggagtaaa tctcaatttt gccgcttggc gtacccagcg catttttcac
      601 cggatcggcg cggaaatcac cataacgaat gtactgttcg ttcttctcgc tgcggcgcat
      661 ttcgatcagt ttattttgct gccagaaggc attaaacatc ggcatcgtca cgcgttgcgc
      721 acgggcacct ttctgagcgg catcatagaa aaatttcagc cacgccattt catctttacc
      781 ttcggtatag atctcttttc cgccaggttt gagtaattca gcaagatcgg caaacacgtc
      841 aaaatcgttg cgcgcttcaa attgcggagc gacagcctgc ttcatcggca caatatgctg
      901 gttgctgtaa tcaccggtca tcgtcaggtc attgcgctca aacgatgtgg tgatcggtaa
      961 tacgatatct gcgtgtttgg ctgctgcggt ccagtagcat tcagaaacga cgatcatctc
     1021 cggtttctgc catgctttaa tcagacgatt agtatcctgg tgatgggtaa agttaccgcc
     1081 acccgcccac cagatcattt tgatattcgg atacgtttgt tctttaccgt tatgctgata
     1141 tttgccgcca ggattttcca gcgcatcgac gatacgggca acaggaatcg ccgtcattcc
     1201 gccatcatca gcggcctcgc tggcctgtcc ggcaatcgcc gcagacattt ctggtagcac
     1261 gccgccaaca cgcgtcgggt tgccaccgtt ggagtaatga taagagaaac caaacccgcc
     1321 gcccggtgta ccaatttgcc ctaacatcgc cgccagcgtc accagcatcc agtgtttctg
     1381 ttcaccgtat tgctggcgct gaattcccca gcctgccatc agcattgtgc gatttgccgc
     1441 catcagttct gcaagtttca caatctgcgc ttccggcacg ccagtaattt ccgccgccca
     1501 ggccgcactc ttcggcgtat tatcgttctt gcctgtcaga tactcttcaa actgcggata
     1561 cccggtagtg tatttttcaa ggaacacttt atcgtgtttg ccttgtgtca tcagggtatg
     1621 cgcaatccct aacatcagtg ccacgtcggt gcccatattc ggtgcgatcc aggtggcatt
     1681 atcgccaaag aattcgatgg tttcggagcg gataggatca atggcaatca ctggtttgcc
     1741 agattttttc agctgatgga agtattccag cccttgttca tcggtactgc tccaggcaat
     1801 ttttaaggta ttcagcgggt tcatgcccca caacaccacc acctgactgt tttccagaat
     1861 cagcggccag gaagtctgct gttcatagac ctccacagaa ccgaccacat gcggcatgat
     1921 cacctgtgcc gctccggttg aataatcgcc gctatgcccg gaataaccgc ccgccaggtt
     1981 catataacgt tgcagtaagg tttgcgcttt atgcaacacg ccagaagaac gccagccgta
     2041 agatccggca aaaatggccg atggtccgtt agctttacga atatgatcgt gttgctcatg
     2101 aatcagtttt aatgcttgtt cccagctcac ctgtacatag gtatcttcgc cacgaccttt
     2161 cgccggttgc agtggattat cgagatagct ttttctcacc atcggatgct gaatacgcgc
     2221 cgtggtgtgt acctgatccg ccgccgtaga ctgtaaggag ttcggtatgg tcttcgccag
     2281 cgcgcctgtc gaagaaacaa tcttgccgtc cttcacttct acgttcatcg ctccccaacg
     2341 tcccgcggtg agaattttgc cgcccttctc ttctgcccat gcaggtaacg gtgcagccga
     2401 tgtcaccacc agcgccccag cggcaatacc gctatgttta ataaattcgc gtcttgttaa
     2461 tgtcataact tcctccctga tcaacgagga tcactgtttc tcggtaatat ctttggcgtt
     2521 gtactggaag taccgcgtca aaatgtccag ttcgttttcg ctcatgctgg ttcgcgcacc
     2581 cattcctttg gcaatggacg gccatgcatt gacggtgtaa tggtcggcgg caataggggc
     2641 atggcagcca gcgcaatagg tatcgtcaag tttttcagcg tattgccata gtggtttacg
     2701 gtccgctaat gcggaatcgg ttagcgcacc ctgtaaagac gcctgacgcc attgattgcc
     2761 gtattcgtca gcctgccatt ccccgtttac cgttagcgcc ttgatacctt cttcacttaa
     2821 tgtggcgagc gccagccgtt gacctgccgc caggtagagc gtgttttcac tgccctgcat
     2881 ttgataaccc tgcaaccgaa caattggctg tttaccactg acatcaacga cggtgagatc
     2941 ggtaccagga gtcacggtag ccaggtcgcc tatgcgagaa gttttgaaag gataaatatg
     3001 tgcgccatta gtaactgaag tagcggcctg actttccagc tcatgcgccg cgttgtcatc
     3061 catttttatt tctggcggga aatgggcaat gcctttatgg caatcgatac aagtttcgcc
     3121 gtccttttgc gctttattat gcattttctg cgcagattca ctttgcgagg aaatatccat
     3181 ggcatcaaaa gaatggcaac tacggcaggt tgcagagtca gttgctttta attctttcca
     3241 tactgtttcg gccatttcct ggcgatgagc ttcgaactta tcgtcactgt ctattttgcc
     3301 gctaacaaat tcatgataaa tatctttaga tgcttttaat ttagcaaata aataatccat
     3361 ccctgacttt ggaatatggc aatcggcaca ttccgcgcgt ataccttttt ggttcgaaaa
     3421 gtggacagtt ccctgatatt cctcaaaagg tttactcatc gagtggcagg aaaggcaaaa
     3481 tgcagtatcc gacgttttat gtaaggcttt ttgcgccagc aataacccgc cgccaccaac
     3541 cacaaccgct atcagcaaaa acaataaccc aatgcgtttt ttccctcgca tagattcctc
     3601 taattaaatt ccaggacacc gataccattg tataaataaa tatacaacga attgactact
     3661 tgcttaattc ggcacaacac tgcctgaaat aatcgataaa gaatatgatt tattacaatg
     3721 taatcattaa ttgctaagga ataacccagt tgttatttag aatatatatt tgtcagtttt
     3781 ggcaatttaa atcacataat gaatgtgaat atatagaata tttctagcac aatgctatgc
     3841 gcactgtcac ccgctcaaca gatcacggca atcgttcgtt ttttatacta ctcagggata
     3901 aaaaaaggcc cctgttgaaa ttgcaggggc ctggtacgag caagcatcat attgggcgac
     3961 atgatgcaac ggtaaaaatc atttggcctg atggcgttca atgattcctt tcatttcagc
     4021 aaccgccgcc ccgtctacga cataacgcga atactcgtcc gcgtgtgcat ctgatgacat
     4081 ggacaatcct tgattacgat aacgcatcgg tgaggcttgc cacgctcccg cggagctatg
     4141 gacttccagc actccggcat cgaggaagtg gtgcaggttt tccgcacgga ctcctgctcc
     4201 ggccataatg attggagcat cacgatgggc aataagttcc ataatttttg ataaaccttg
     4261 cagtgcgtct gatttttgcc ctgatgtcag tacccgggca atgcccaatt ccgtaagatt
     4321 attgagtgta tttaaagggt tagcgcacat atcgaaggcg cgatgaaaag tcactgccag
     4381 cggaccggca gcagccatta ttttttccat tcgtggcata tcgacattcc cgtcaacatc
     4441 gagaacgccc gtcaccagtc caggaaaacc taattcgcgg actgtgcgca catcttcaag
     4501 aatggcggca aactcaccgt cgctgtagca aaaatcacca ccgcgtgggc ggataatcgg
     4561 atgcactggg atcgtcaccc gctggcgcac ggatttcagt acccccaacg acggcgttag
     4621 gcccccctct tttggagctg cgcataattc aactctgtca gcgccgtttt gctgcgccgt
     4681 tagcgcgcat tccatgctgt aacagcaaat ttccagtaat gccatttttg ctccttagtt
     4741 acgccgactg ctcgctggca acgatctctt caatggacca cggatgaaac ttaatggttg
     4801 ttttaccatc ggtgaccgcc agcgtcggat tcggtaatcg ttcatgctca ccttttggcg
     4861 aactggtttt aactgagatc cccggcaggc tgagtccttc atcagaaagc aatgccagcg
     4921 cacgggcatt cagcgtttct ggatcacccg gtagaacgat ttcaatatgt tcccaacctt
     4981 cgtgcgggta acgtttttcc ccgggccacg gtagctccac aatggaaaac tgccagtgcg
     5041 caacctgtag cggttcatgc aatttaaaca aacaaatcgg tctgccattg atcatatttt
     5101 ctgacaaaag ctcgccgcac tgttcaaacc cgcgacgcca gcgttcagcg gtgacgtttt
     5161 gatggcaacg caaagaaatg tgatcggcag tcagcggagt gatatccaac cccagacggc
     5221 gggaaagttc atctaatgcg tgggtaaatc gcggtaaatc cgatgcaata tcctgcagct
     5281 cgtcgataga ttgccagttc gccataatca ttcttcgtct ttcattaaaa gcgttaattt
     5341 accctgttgc cctgcgccaa ccaaccgctg atttcacgcc gcttctgatg caatagtgaa
     5401 aacggcaata cgccacgcgc acgttgctga cgaaaacagc catttgcagt atactcccgc
     5461 cctaatttct ttaactggtg cgggtaattt ttgctcgctt catcaatgta aggtattccg
     5521 gtgaatattc aggctcttct ctcagaaaaa gtccgtcagg ccatgattgc ggcaggcgcg
     5581 cctgcggatt gcgaaccgca ggttcgtcag tcagcaaaag ttcagttcgg cgactatcag
     5641 gctaacggca tgatggcagt tgctaaaaaa ctgggtatgg caccgcgaca attagcagag
     5701 caggtgctga ctcatctgga tcttaacggt atcgccagca aagttgagat cgccggtcca
     5761 ggctttatca acattttcct tgatccggca ttcctggctg aacatgttca gcaggcgctg
     5821 gcgtccgatc gtctcggtgt tgctacgcca gaaaaacaga ccattgtggt tgactactct
     5881 gcgccaaacg tggcgaaaga gatgcatgtc ggtcacctgc gctctaccat tattggtgac
     5941 gcagcagttc gtactctgga gttcctcggt cacaaagtga ttcgcgcaaa ccacgtcggc
     6001 gactggggca ctcagttcgg tatgctgatt gcatggctgg aaaagcagca gcaggaaaac
     6061 gccggtgaaa tggagctggc tgaccttgaa ggtttctacc gcgatgcgaa aaagcattac
     6121 gacgaggatg aagagtttgc cgagcgtgca cgtaactacg tggtaaaact gcaaagcggt
     6181 gacgaatatt tccgcgagat gtggcgcaaa ctggtcgaca tcaccatgac gcagaaccag
     6241 atcacctacg atcgtctgaa cgtgacgttg acccgcgatg acgtcatggg tgaaagtctc
     6301 tacaacccaa tgctgccggg tatcgtggcg gacctgaaag ccaaaggtct ggcagtagaa
     6361 agtgaaggcg cgaccgttgt attccttgat gagttcaaaa acaaggaagg cgaaccgatg
     6421 ggcgttatca ttcagaagaa agatggcggc tatctctaca ccaccactga tatcgcctgc
     6481 gcgaaatatc gttatgaaac actgcatgcc gatcgcgtgc tgtattacat cgattcccgt
     6541 cagcatcaac acctgatgca ggcatgggcg atcgtccgta aagcgggcta tgtaccggaa
     6601 tccgtaccgc tggaacacca catgttcggc atgatgctgg gcaaagatgg taaaccgttc
     6661 aaaacccgcg ctggcggtac ggtgaaactg gccgatctgc tggatgaagc cctggagcgt
     6721 gcacgtcgtc tggtggcaga aaagaacccg gatatgccag ccgacgagct ggaaaaactg
     6781 gctaacgcgg ttggtattgg tgcggtgaaa tatgcggatc tctccaaaaa ccgcaccacg
     6841 gactacatct tcgactggga caacatgctg gcgtttgagg gtaataccgc gccatacatg
     6901 cagtatgctt acacgcgtgt attgtccgtg ttccgtaaag cagaaattaa cgaagagcaa
     6961 ctggctgcag ctccggtaat catccgtgaa gatcgtgaag cgcaactggc agctcgcctg
     7021 ctgcagtttg aagaaaccct cactgtggtt gcccgtgaag gcacgccgca tgtgatgtgt
     7081 gcttacctgt acgatctggc cggtctgttc tctggcttct atgagcactg cccgatcctc
     7141 agcgcagaaa acgaagaagt gcgtaacagc cgtctgaaac tggcacaact gacggcgaag
     7201 acgctgaagc tgggtctgga tacgctgggt attgagacag tagagcgtat gtaatcgcgt
     7261 tatacggcaa cagccgatgt cattgcagac atcggctttt ttatcattaa cgataattta
     7321 caatcacttc attccgttga atctttagcg gcggagttag ccgcccaccg ccaggcactt
     7381 cccagataaa gcgcaacggt tctgccgccg gtataccgga aaaggccatg gtggttccac
     7441 tctgcccctc caattcgaca caacgagatt gtgaacacaa gcgaacccgc agtcctgcag
     7501 gtgtcggacc gataagctga taacgccacg ccaccagcgt catcaatcct gaagcaggtt
     7561 gtcgcgtaga aagaggcgct gacgacatcg attcaccgcg atgatttagc gtaacgccca
     7621 cgctactcgc ctgccacatc ccctccccgg cggcttgcac cagcagcgga aacaataata
     7681 ttgctaataa ggctctcatt atttgccgcc aatcgtcgcc gtcatacgga tatgtcggtt
     7741 atctgatagt tccagattcg acagcaccac taactgcggc aagctgcggc gcaggaagcg
     7801 agacaataat ggtcgtagcg cgtggttcac caacaatacc ggcggcgcac ccaacatctc
     7861 ctgacgggat agcgcttcct gagtttgcgc cagtaaacga tccgccagcc ctggctccag
     7921 tccaccaccg ccttgcaacg cctgtagcaa caaacgttcc agcggtgtat cgaggccaat
     7981 aacatggact tcatctttgc caggaaacca ctgctgggta atcgcccgtc ccaacgctac
     8041 gcgcacgaca gcggttaatt catgcggatc gctttggatg ggcgcatgtt ccgccagcgt
     8101 ttcgagaatg gtgcgcatat cgcgaatcgg cactttttca tcgagcagat tttgcagcac
     8161 tttatgcagt gtggtaagcg tgacgacgcc aggaacgaga tcttccgtca gctttggcat
     8221 ctcctgggcg acgcgatcca gcagctgttg tgcctcctga cgaccaaaca gctctgcggc
     8281 atgctggcta atgaggtggt taagatgcgt tgccaccacc gtgctggcct caaccacggt
     8341 gtacccctga atctgcgcct gttctttaag cgcactttca atccagatag cattcaggcc
     8401 aaatgccgga tcaacggtcg cttcaccagg taatgttccg gcggcagtgc ctggattaat
     8461 tgccagccag cgccccggat aagcatcacc actccccatt tcgacacctt tcatcaagat
     8521 acgatagcgg gctggttgca aatccatgtt atcgcggatg tgcaccactg ggggtaggaa
     8581 gcccatctcc tgggcaaatt tcttgcggat actgcgtata cggcccaaca actcaccatc
     8641 ctgctgaaaa tcaaccatcg ggatcaaccg ataccccact tccattccca gagaatcttc
     8701 cagttgtaca tcgttccacg ttgcttcgac taccgaatta ttctctgcca tttttaccgg
     8761 ttttggttcg gcaggcgctt tttgttcacg tccgcggatc caccaggcca gccccagcaa
     8821 tccggcagtg aacagcaaaa ataccaggtt tggcattcca ggcaccaggc cgagtaaacc
     8881 gagcacggcg gcgcttaata acataacgct tgggttactg aaaagctgat tcaccatctg
     8941 ctcgccaaca tcctgatcgg tgctgacacg cgtaacgatg acccccgcgg cggtagaaat
     9001 caccaacgcc ggaatttgtg ccaccagacc gtcgccaatg gtcaatagcg tataactttc
     9061 cgccgcgtgc cccatgctca tgccatgttg cagcacaccg accagcaatc cgccgacaac
     9121 gttaatgacc atgatgagga tcccggcgat ggcatcgccg cgaacaaact tacttgcccc
     9181 gtccatcgag ccgtaaaaat cggcttcctg agtcacttcg gagcggcgtt ttttcgcttc
     9241 atcttcacca atcaatccgg cgttaaggtc ggcgtcaatc gccatctgct tacccggcat
     9301 accatcgaga acaaagcgcg cgcccacttc cgcaatacgc ccggcacctt tggtgataac
     9361 cataaagttg atgatcacga gaatgacgaa caccacgata ccgatagcga aattgccacc
     9421 gacgaggaag tgaccgaacg cttcgaccac ctttccagcc gccgccgcgc cggtatgccc
     9481 ttccatcaaa atgatacggg ttgaagccac gttaagtgcc agacgcaaca gcgtggtaaa
     9541 caacagaatg gtcggaaacg cagcaaactc gagcgtgcgc tgggtaaaca tcgccaccag
     9601 caacaccatg atcgacaagg caatattgaa ggtaaacagc aggtcgagta tgaatgcggg
     9661 cagtggcagc accatcatcg acaagatcaa caggatcaaa atcggtccgg caaggatctg
     9721 ccattgtgtc gatttcaggt ttgcgggcag gcgcagcatc gcggccagat tactcatggg
     9781 tcggtttctc gttaataaaa tccagggctt ccggcaccgg aagatgagta ggttgtacag
     9841 ggcgctgtcc accagccaga cgccagcgtt tcagttgcca gacccaggcc agcacttccg
     9901 ccaccgcggc gtacagttga cccgggattt gttgaccgat ctccgcatgt cgatacagcg
     9961 cacgcgccag cggcggcgct tcaagcgtcg ggacgttatt ttcagcgcca atttcacgaa
    10021 tgcgcagcgc gaccagccct gcacctttag cgaccacttt cggtgcgctc attttgtttt
    10081 cgtcatactg caacgctacc gaatagtggg tcgggttatt gacaatgaca tccgctttcg
    10141 gcacatcggc catcatccga cgccgtgcgg ccgctcgctg catctgacgg atccgccctt
    10201 taacatgggg gtcgccttcg ctttgtttga actcatcacg aatatcctgc cgtgacattc
    10261 gcagcttttt caggtggctg aagatttgga aaaagacgtc aaatcccacc attggaatga
    10321 caccaagcac caccagcagc gcgcatagcc ctaccagatc cattgcatta cccatggcgg
    10381 taatcggaga ctcggccatt aagcgcatca tctgcggcca gtgataccag agaaaaaacc
    10441 ccgtcacgct gccaaccagg atggttttca aaattgcctt aagcaactcc gcgccagtct
    10501 gtgccgagaa cgtccgttta atgcccggta gcgggttgag tttggaaaac ttcggctgca
    10561 aggattttcc gctaaatacc agccccccca gcataaccgg agaaataatc gccaccagca
    10621 ccacgccgct aatcagcggt agcagcgcca gcatggcttc tctgatcagc agaataatct
    10681 gcccgaggat cagattcggg tcattgataa tactgtgatc aaaatgtagc cctgcggaga
    10741 gcatgcccga caatcgacgg gccagcgaca caccgccaaa ccagataaca ctaacgccca
    10801 ccagcaaaat cagcagtgaa gtcagttcac gggaacgcgg gatttgcccc tcttcccgcg
    10861 ctttttctag tcggtgaggt gtgggggcct ctgttttgtc gtcgctctcg tcagacacgt
    10921 cgccaatcct ggaaagagta ttaagcgtaa atgatgccag agcgcaaagc gttcaatggt
    10981 ttgagtaagg ggcaaaacag gcgggattta gggcttttac tgccacacat caagcatagt
    11041 atgcgtttgt cggatgcggc gtcatcgcct gatatgacgt ggtcacgtca catcaggcaa
    11101 tacaaatcaa aatccaagac tatccaacaa atcgtccacc tgaccctgac tggctaccac
    11161 accggctttg ctggtatcga cctgaggtcc attaagcaaa ctctggtttt cacgttttgg
    11221 acgcgactcc tgttccggga tgttttccaa caacaccatc agcaactgac gttcgatctc
    11281 ctgaatgaca tccatcatcc gcttaatgac ctgcccggtg agatcctgaa aatcctgcgc
    11341 catcatgatt tccagcagtt gcgcgttagt aaagctggta tgcgcgggga catctgccag
    11401 aaattgccgt gtatcgatca ccagttcacg ggcgtcggca aggtcaatcg gatcggcaaa
    11461 ccagtcatcc caacgttggg ttaacgcttt tgctgatttc tccatttgat cctgatgcgg
    11521 ttgtgacgcc tcaacactgt tcagcgcccg ctccgcagcc tgggcggtca tctgcacaac
    11581 atagtacaaa cgatcgcgcg catcggggat ggcttccgct gcttcggcaa tggcctgatc
    11641 cagccccagt tcccgcaaac tgtcgcgcag catacgcgtc aggctgccga tgcgcgcaat
    11701 gatatcgcca gctgaatgct cgtcagcagg tttgattgat ggttgcatca tagtcgcatc
    11761 ctcacatgcc cagtttctca aagattttgt tgagtttttc ctccagcgtc gcggcggtaa
    11821 atggcttcac cacatagcca ctggcccccg cttgcgccgc agcaatgatg ttctctttct
    11881 tcgcttctgc agtcaccatt aacactggca atgccgacat cgcgccatcc gcacgaatcg
    11941 ttttcagcaa ctccaggcca tccatattgg gcatgttcca gtcggagata acaaatccat
    12001 aaccgcctgc ctgcaactta ttgagagcgt cgacgccatc ttccgcttcc tcaacattat
    12061 tgaatcccag ctctttcagc aggttacgca ctatgcgtcg catggtggaa aagtcatcca
    12121 caaccaaaaa tttaagttct ttatccgcca tttcacactc ctgatttaaa tacgtatcgc
    12181 ctgtccggca ctaatttttg ccagcatttg ctgacttacc tggctaagat cgaccacttc
    12241 gcagacacca cccatattga tggcctcgcg cggcatgccg aacaccacgc aacttgcttc
    12301 gttttgcgca agggtccatg cccccgcctg acgcatcgcc aacattcccg ccgcgccgtc
    12361 gttgcccata ccggttagga ttaccccaac cgcattacgc cccgcctgtt tggccacaga
    12421 atggaacaac acatctaccg atggccgatg gcgattaacc gccgggccat cgtgaatttt
    12481 gatttgataa tttgcgccac tacgcgccag ctccatatgc cgatcgcccg gcgcgatata
    12541 ggcatgtccc ggcaagacgc gctctccatc ttcggcttct ttaaccccga tctggcaaag
    12601 cttattaagt ctgtcggcaa aagagcgggt gaaaccgggc ggcatatgct gggtaattaa
    12661 cagtgccgga ctggaaagcg gcaacggttg cagtacgtga cgaattgcct cagttccccc
    12721 cgttgaagca ccaatcgcaa tcagtttttc agaactcaac aacggccccg ccttcagcgt
    12781 tgtcggtgcc gacaatggct tatgtgctgc aaggctcgcc tttgctgccg tacgcacctt
    12841 ttcagcaatc atttcgctat acgccagcat tccttcgcga atacccagtt gcggtttggt
    12901 gacaaaatct atcgccccca actccagcgc gcgcagcgtg acttctgacc ctttgccggt
    12961 cagggaagaa accatcacaa cgggcattgg acgcaaacgc attaattttt cgaggaaatc
    13021 cagtccgtcc atccgcggca tttcaacatc cagcgtcaat acatcgggat tgaatttctt
    13081 aatcaaatca cgcgcaacca gcggatcagg ggcggtcgcc accatttcca tgtcgctatg
    13141 gctgttgatg atttctgtca tgatctggcg catcagtgcc gaatcatcga cagataacac
    13201 cctgattttg ctcatcgtta atccttactt agcgcataca ccgtctgacc acgcagcgtg
    13261 aagcggcgct caaggtggct aaagttttca gagtgacccg caaacagcaa tccgtcgggt
    13321 ttaaggagcg aaacaaagcg gcgcaaaatc tcctgctggg tagtttgatc gaagtagatc
    13381 atgacgttac gacagaagat cgcatcaaac ggccccggca cggtgtactg tttcgccagc
    13441 aaattcagcg gggcaaaatc aacatagttc gccagctcct gacgcacgcg taccagccct
    13501 tcatgcggtc ccgtccctcg catgaaatac cgttgcagtt gctgcggcgt caggtttttc
    13561 aactcttcat ggcgataaat accgcttctg gctttttcca gcacttcggt gtcgatatcg
    13621 ctggcaaaca ctttccagcg tccgggcgcg gtgcccaatg tatcagccag cgtcatcgct
    13681 atgctgtacg gctcttcgcc ggttgaagcc gccgcgctcc atacgcgata ctcgccagaa
    13741 cggcgacgtg cgtgatccgc gagcagagga aaatggtgtg cctcacggaa aaatgccgtc
    13801 agattcgtgg tcagcgaatt gataaacgcc tgccactcac cgctgtgctg attagattcc
    13861 agcaagttca ggtaatgacc gaaatccgcc agtcccagcg cacgcaaacg acgaaccagt
    13921 cggttgtaaa ccatgtcgcg tttatggtca gccagaacga tcccggcgcg ttgatagatc
    13981 aattgactta tccgccgaaa atgcgcgtcg gaaagcgcca ggcgctcggt catctgtaac
    14041 aataaagacg tttgcccaca gggcagagat gaagtcatag cgccttctca atcacttcag
    14101 gataccactg gcgcaatttg taactgcgcc gactcatgtc gtgctacttc atgttcttca
    14161 agggtaaata ccgccacacg cgacgaaaga tggtcggcct gattcagtcg ttgcaaatcg
    14221 tcgcgaaatg cccaaaagac atgccgttac tgccaatctg caagatcccg cagagaatca
    14281 aaattaaaaa cagcgtggtc gaaattcgaa tacgattaaa catcaacgct ccccatcagg
    14341 cggcaatgac cgctttagta aatactcgtc aaaatgtttc ccagtttgga tcttgttcag
    14401 caattcgcag tcgtggctgt gccggtggtt gctcactggc aggacgggat ggtgtttgcg
    14461 gtttattggt gagtgggctg gctgccagac ggaacgcgga aaccgcttgc gttaaacgac
    14521 tcgcctgttc ttccagcgca gctgcggcgg cagctgattc ctgcaccagc gatgcgttct
    14581 gttgcgtgac gcgatccatt tccgaaaccg ccaatgcgac ttgatcgatg ccacgactct
    14641 gttcatccga tgctgatgca atctcgccca taatgtcagt cacgcgagtg acagcattga
    14701 cgatattgtt cattgtttcc cctgcgcttt cgaccagcac cgaaccggta tcaacgcgcg
    14761 agacggagtc ttcaatgagg gctttgatct cttttgccgc ctgggcgctg cgactggcaa
    14821 gattacgcac ttcgcccgcc accacggcaa aaccacggcc ttgttcaccc gctcgcgcgg
    14881 cttcaacagc ggcattcagc gcgaggatat tagtctggaa ggcaatacca tcgataacgc
    14941 tgataatgtc ggcaattttc ttcgaactat cggcgatctc atgcatcgtt ttcactacgc
    15001 catccaccac tttgccgccg tgctgggcgg tgtcggaggc actttgcgcc agttgcgagg
    15061 cctggcgggc gttatcggcg ttttgcttca ctgtcgcggc gagctgctcc atgctggcgg
    15121 cagtttcttc cagcgcggat gcctgctgtt cagtacggga ggaaagatcg gtgttgcccg
    15181 ccgcaatttc acgggtaccg gcatagatgg catctgaacc ttcgcgcaca tgagtgacgg
    15241 tgtcagtcaa agagcgttgc atatgtgaaa cgctctgcgc caggtcgccc atttcactgc
    15301 gcccgtcaat ggtcagggta ttcgccaggt taccaccggc aatttcgcga atatgcgcaa
    15361 taatttttgc cagcggtgta agcaacatac ggcgaatgcc gtaccacgcc gccagcagaa
    15421 tcaataccac caccagcgcg ataaccgcca gttgccactg ggcaaatcgg taatcatctg
    15481 cgttgtcagt gacgatatcg cgatacagtt tttcactgct gagggcgtac tgagcaaacg
    15541 cttctcccat tgcattttgc attccctggg ttggctgagc gaaataagct ccagtattgc
    15601 cataatcaag ataatcaatc agttcagtta acgctgtgtg atagttttta tatttttcat
    15661 caatattacg actggtagcg accatttcag gtaacggtgc catgcttttg aattttttat
    15721 aatgagtcgc ggcctgggcc aatgttttcc tggcgctatc gagcaattca actttggcat
    15781 tactttgctg attggatgaa tccatcatca tccgcaccgc tgaacgactc aggttaatgc
    15841 gcgtttgtag cattaaatcc catgttgacg tcagctcgct ctgctgttcc cgtaattgat
    15901 tggaaaccac aaagctcttc tggctatggt gaagggaaga aaaaaacaga ctgccggaaa
    15961 taagctgtaa cagtgcgaat acccccagca ccattaccaa cagcgtgact acgcggatac
    16021 ggttaatcat aaggcacctt cctgaaaaca agttgatctc gttatcggca aggagggggg
    16081 aaactttatt gctgatgcca cccgccgcga aattgaaata aaaaacccga tgcgcagatc
    16141 atcgggttca tttcaattga ggacatcggg agaattacgc cacttctgac gccgcgctat
    16201 ctaacagcgc catctcttcg ctgttcagca gtttttcgat gttcaccaga atcaacatgc
    16261 ggtcgcccag tgcgcccagt cctgtgagat attcggttga aagcgtcacg gcaaattccg
    16321 gtgccggacg aatttgctcc gccgtcaatg aaagcacgtc tgagacgccg tcaaccacga
    16381 tgccgaccac ccgctgtccg agattcagga cgataactac cgtgttgtcg ttatagtcca
    16441 catccacctg gctgaactta attcgtaagt caacaatcgg cacaataacg ccgcgcagat
    16501 tcgtgacgcc tttgataaac gctggcgtgt tcgcaatccg tgtcacctga tcgtagccac
    16561 ggatctcctg cactttcaga atatcaatac cgtactcttc atcaccaagg gtaaatacca
    16621 gaaattcctg gcctgacggc tcgctggcca gctttgttac attcgtcata ccggtcatat
    16681 tgttaccttt ttactcattc aggcggcggt gttcgccata cgttgttcgc ggtttatcgc
    16741 ctgcaaggcg gagacatcaa caatcagtgc cacgctgccg tcgccaagaa tggtcgcagc
    16801 agaaatgccg gggactttgc gatagttact ttcaaggttt ttaaccacaa cctggtgttg
    16861 accaattaat tgatccacta gcaaggcgta gcggcgaccg ccactttgta agatcaccac
    16921 aattccctgg gtggcttcgg ttttcgcgcc cgcgacgttg aacactttcc acagttcgac
    16981 gataggcaga tattcacccc gcacttccag cacccgctcg ccgccagcca gtggatgcag
    17041 atcggcttca cggggttgca gtgattccat gacagcattc agcggcagaa tgaaaacttc
    17101 atccgcaacg cgtacggaca tgccgtcaag aattgccagc gtcagcggca gtaaaatgcg
    17161 gatcgtagtg ccagtaccct gcatcgactg gatctcgaca tgaccgccca tctcctggat
    17221 attacgttta acgacgtcca tgccgacgcc acgcccggag acgtcggtga cctgctccgc
    17281 cgtggagaag ccaggtgcaa atatcagcat tgcaacttcg tcgtcgctca tgttttcgct
    17341 gacggtcaga ccttgcgagg ccgcttttgc cagaattcgt tcacggttta gccccgcccc
    17401 atcgtcggtc acttcaatgc aaatgttgcc gccctgatgt tcggcagaca gaattaaatt
    17461 tccgacgctg tttttacctg cagcgagccg tttttctggc agttcaatac cgtgatcgag
    17521 gctattgcgt accaggtggg tcagcgggtc gataatgcgt tcaatcaggc tcttgtcgag
    17581 ttcagtagaa ctgcccacca gcgtcagttc tacctgcttg ccgagttttc ccgccagatc
    17641 acgcaccagc cggggatagc gactaaagac atattccatc ggcatcatgc gaatcgacat
    17701 cactgattcc tgcaaatcac gggcgttacg ttgtaactgc cccatgctgg taatcaaatc
    17761 accatgatta accgggtcca gttcgctgga acgctgggca agcatggact gggtgatgac
    17821 cagctcaccg acgaggttaa ttaattgatc aaccttttct accgctacac ggatgctggt
    17881 ggattcactg ctgcgcgtcg ttttttcccg ctccacgcga ccggttggcg cttgttcggc
    17941 tgccagttta agcattggtg aggtggatat ttttggcgag acgtctactg tttcaaaggt
    18001 aatctgatcg gcttcaatca caaaacagag taccgctgtg atgtcatctt cggcgatgtc
    18061 gcccggtaat attgccgaga gggaatcagc ccctttcacc acgtcagtta acgttgtcag
    18121 atgccccagc tcttcttcca gcaggtcgac ttcgccggcc ttcaggcgcg aaaggataat
    18181 tcgtcgcggt gactgactac gactctgctc atcttgtggt tcacttttgg caaccacact
    18241 taatcgggtc actgcggatg gcgtttcgcc tttcgcttct aatgccagtt gacgcaaggc
    18301 ctggcagata taatcgaagc tggcggcatc cggctcttgc gactgtttat aagcgtcgag
    18361 ctgttcttgc atgatgtcct tcgtttccaa aaacagattg ataatgtcgg tgttgagttg
    18421 catctcacct cgtctggctt catcgagcag gttttccatc agatgcgtgg tttcctgcaa
    18481 aacgctgaag ccaaaggttc ctgcccctcc tttgatcgag tgggcagccc gaaagatggc
    18541 attcaattgt tcggcatctg gcgcttccgg ctgcaaaacc agcagatgct gctccatatc
    18601 agccaacagt tcgtccgctt catcaaaaaa tgtctgataa aaatcgctta tatccatgct
    18661 cacgctgtca cctcggttcg gctgatggca ttgtgggaac actgacctgt ggtgcaacct
    18721 caggtttttc cagggcgctt actggctcat tctggctttc ggcgttttca tgcaaaatgg
    18781 cctgttcggc ttgtttgttc agtaccagca ggctgatgcg acggttgacg gcatcatcag
    18841 gtccgcgatc gcttaagcgc atcgttgccg ccatgccgac gacacgtaac actttgccgc
    18901 cattcaaccc gccaaccatc agttcgcggc gggatgcatt ggcacgatcg gcagaaagct
    18961 cccagttgct gtaacctttc tcaccgctgg cgtagggaaa atcatcggta tgacccgaga
    19021 ggctaattcg gttgggaata ccgttcagta cgggcgcgat ggcgcgcaga atgtcgcgca
    19081 tatagggttc gacgtcggca ctgccagttc taaacatcgg gcgattctgg ctatcgatga
    19141 tctgaatacg tagaccttcc tggaccagat cgattttgag atgtggacgt aacgcccgca
    19201 gtttcggatc ggactcaatc aactggtcga gatcgccacg caatttccgc aatcgacttt
    19261 gctccatgcg ttttttcagc tcttcgatgt tcggccgctt attcacttcc ccctggcttt
    19321 gggtgtaatc atcaccaccg ccgggaattg ggctttcact attagaaatg cgatcgccgc
    19381 ccgtaaccgc tgtcgccagc ggagtccgga agtactccgc aatctgaatc agctcttttg
    19441 gactggagat agagatcagc cacatcacca gaaaaaaggc catcattgcg gtcataaagt
    19501 cggcataagc aatcttccac gatccatgtg ctgccccgtg gcttttggct ttacgtcgtt
    19561 tgacgacaat aatcggatgc gcttgattct tcatgcttcc tcggttgtcg tctgttgttg
    19621 cggatttttc accgcacgca catgctcttc cagctcaata aacgacggac gttcgctgga
    19681 atagagcgtt ttgcgaccaa actcaacggc gataggcggt gcgtaaccgt tcagatttga
    19741 aagcagagtg actttgacgc actgcatcat tttgctggtt tcggcgcttt tctgacgtaa
    19801 aacactcgct aatggggaaa taaatccgta agccaataaa ataccgagga aagtccccac
    19861 catcgcatga gcgataagcg cccccagctc ggcggcagga cgatcggctg aacctaacgc
    19921 gtgaactacc cccattacag ccgcaacaat accaaaagcc ggaagtgagt ccccgaccag
    19981 cgccagactg ttcgccggga cttctgcctc gctttcgtgc gtctcaattt cttcatccat
    20041 cagggcttcg atttcgaagg tgttcatgtg accgctgata atcaggcgca gataatcgac
    20101 gataaattca agcatgacgc tatccgcaag gatgcgtggg tagctggcga agatctcgct
    20161 ctcacgggga ttttcaatat cgcgttccag cgaaaacatc cccatctgcc gcgatttcgc
    20221 catcaaccga taaagcagag ccagcagatc catatacatt gctttggtgt atttggagcg
    20281 acgaaacagc aacggcagcg ccttcagcgt gcctttaatc gctttgccat tattgccgac
    20341 gataaacgac ccaatccctg caccggcaat aatcaccagt tcagcgggtt gatagagtgc
    20401 tccaaggctt ccaccggtca tcaaataacc gccgaaaact gtaccgagaa caaccaggta
    20461 acctaataag ataagcacga catcatcctt ccactgttga ccatgacagg atgttcagtc
    20521 gtcaggcgtt aacacgcgat aggggcaaaa aaaagcagcg gtacgtcgtt accgctgctg
    20581 gaatgtttcg ccacaccgta tcagttaaac agcctgtact ctctgttcat ccagcagttg
    20641 tgggataata tcggcaggat tctgggaaag tttacgtctt tttactgccc gggatggcgg
    20701 ctgacataag ctgcaggcaa agctgccaac aggctggtga gcatgggtaa taaaattgcc
    20761 gccgcagcag ttgcagctgg aaagttgcag taatccactt tcaacaaacc gcaccaatgt
    20821 ccaggcacgg gttaatgcca gcagcggtcc ttcttctgct tgcgggcact gttcaaggta
    20881 taaacggtag gctttgatca ccgcatcgac gccattacac aagccagttt tcagtaaaaa
    20941 ctgccatgca ttacagaaca tcgaagcatg aacattttgt tcccaggtca taaaccagtc
    21001 ggttgaaaat ggcagcatgc ctttcggcgg tgggcttccg cgcagttctt tatagagttt
    21061 tatcagacgt ccgcgactta actgtgtttc gctttccagc atctgcaaac gagcgcccag
    21121 ggtgatcaat tccattgcca gctgaatatc ccgcgcttcc tgaacaatgc ttttttcact
    21181 catgatcagg cccttttctt gcgcagcgct tcttcaggct gattaacatc attcagcaag
    21241 cgtgttgaga gcatgatgcc ggtatgaatt tgctggagat cgtcaacgcg ggaatcttgc
    21301 gtcaactgag taatcgtctg gtggctgtca aaacggaagt gacaaaccag ttgattggtt
    21361 tctgccagct taaccatttg cggaagagtc agtgccgcta acgttgtcgc catttcttca
    21421 tttatgccga gacgaaacat agcggacgct ttgtcctgaa caatcagacg ctgtgcaagt
    21481 agtaaatatg acaagttgat gtcataaatg tgtttcagca actcggaggt atgcattatt
    21541 cccacccaga ataaccaact ttatttttat gcggtctcac cgcaccccgt gatgtcgccg
    21601 ggaagccccg gtaaaaaata attagcatta gaatagttgc gataagctgc aataagcaga
    21661 cccacctttt tggtttaata agtccttaca aatagaaggg ggtctttaca cttatctaag
    21721 atttttccta aatcgacgca actgtactcg tcactacacg cacatacaac ggaggggggc
    21781 tgcgattttc aataatgtgt gatgcagatc acacaaaacg ctcaattact taacataaat
    21841 gtataagtca tacttttgtt ttgggtgtat ttcaatctgt taaaaaattt ttcgctacac
    21901 tggcaagcaa aaatgaaaca ggaataatcg aaatgggatg ttgcgtacag ttaaaataac
    21961 tcac
//
LOCUS       DAPOXO010000083        21719 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPOXO010000083 DAPOXO010000000
VERSION     DAPOXO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21719
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.083"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            214..549
                     /locus_tag="ROH59_003836"
     CDS             214..549
                     /locus_tag="ROH59_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HDX4806266.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
     gene            709..1152
                     /gene="yjdN"
                     /locus_tag="ROH59_003837"
     CDS             709..1152
                     /gene="yjdN"
                     /locus_tag="ROH59_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HDX4806267.1"
                     /translation="MPLSPYLSFAGNCSDAIAYYQRTLGAELLYKISFGEMPKSTQDS
                     AENCPSGMQFPDTAIAHANVRIAGSDIMMSDAIPSGKASYSGFTLVLDSQQVEEGKRW
                     FDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVIKQQPTQ"
     gene            1285..2073
                     /gene="phnC"
                     /locus_tag="ROH59_003838"
     CDS             1285..2073
                     /gene="phnC"
                     /locus_tag="ROH59_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HDX4806268.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSVGSHIELLGRTVQREGRLARDIRKSRANTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSYFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGCSQQFDNERFDHLYRSINRVEENAKAA"
     gene            2098..3114
                     /gene="phnD"
                     /locus_tag="ROH59_003839"
     CDS             2098..3114
                     /gene="phnD"
                     /locus_tag="ROH59_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4806269.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLNPAYAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIWKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQSVKDNKGLNEQDKLAKTTAIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            3219..3998
                     /gene="phnE"
                     /locus_tag="ROH59_003840"
     CDS             3219..3998
                     /gene="phnE"
                     /locus_tag="ROH59_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDX4806270.1"
                     /translation="MQTITIAPPKRSWFSLLSWAVVIAVLVVSWQGAEMAPLTLIKDG
                     GNMATFAADFFPPDFSQWQDYLTEMAVTLQIAVWGTALAVVLSIPFGLMSAENLVPWW
                     VYQPVRRLMDACRAINEMVFAMLFVVAVGLGPFAGVLALFIHTTGVLSKLLSEAVEAI
                     EPGPVEGIRATGANKLEEILYGVLPQVMPLLISYSLYRFESNVRSATVVGMVGAGGIG
                     VTLWEAIRGFQFQQTCALMVLIIVTVSLLDFLSQRLRKHFI"
     gene            4019..4744
                     /gene="phnF"
                     /locus_tag="ROH59_003841"
     CDS             4019..4744
                     /gene="phnF"
                     /locus_tag="ROH59_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HDX4806271.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDSGSLHDFLREQTGITLRRSQTRISARRAQAKECQRLEIPNLSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            4745..5197
                     /gene="phnG"
                     /locus_tag="ROH59_003842"
     CDS             4745..5197
                     /gene="phnG"
                     /locus_tag="ROH59_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDX4806272.1"
                     /translation="MHADTATRQHWMSVLAHSQPAELAARLNALNINADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVLGRDKQHAERCALIDALM
                     QQNRHFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            5194..5778
                     /gene="phnH"
                     /locus_tag="ROH59_003843"
     CDS             5194..5778
                     /gene="phnH"
                     /locus_tag="ROH59_003843"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDX4806273.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLAAPLSNDIVNQSLRFHTNASLVNQPEQATFAVTDEAIS
                     SEQLNALSTGTAVAPEAGATLILQVTSLSGGRMLRLTGAGIAEERMIAPQLPKCILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            5778..6842
                     /gene="phnI"
                     /locus_tag="ROH59_003844"
     CDS             5778..6842
                     /gene="phnI"
                     /locus_tag="ROH59_003844"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HDX4806274.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTGMRLE
                     RRISAIYKDIPGGQLLGPTYDYTHRLLDFTLLANGETPTLTTADSEQQPSPHVFSLLA
                     RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDIFIVPEELGFAVNVGELLMTECEMVNGFIDPPDEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEQNHG"
     gene            6835..7680
                     /gene="phnJ"
                     /locus_tag="ROH59_003845"
     CDS             6835..7680
                     /gene="phnJ"
                     /locus_tag="ROH59_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDX4806275.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     LIQTRHRIPETPLTEDQIVIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKSQ"
     gene            7677..8435
                     /gene="phnK"
                     /locus_tag="ROH59_003846"
     CDS             7677..8435
                     /gene="phnK"
                     /locus_tag="ROH59_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HDX4806276.1"
                     /translation="MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIRYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVMELNLAVVIVTHDLGVARLLADRLLV
                     MKQGKVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            8546..9226
                     /gene="phnL"
                     /locus_tag="ROH59_003847"
     CDS             8546..9226
                     /gene="phnL"
                     /locus_tag="ROH59_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HDX4806277.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLQGASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKARGAAIVGIFHDETVREQVADR
                     LHPMGVSS"
     gene            9223..10359
                     /gene="phnM"
                     /locus_tag="ROH59_003848"
     CDS             9223..10359
                     /gene="phnM"
                     /locus_tag="ROH59_003848"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDX4806278.1"
                     /translation="MIINNVKLVLENEVVHGSLEMQDGKIRAFAESQSHLSEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVEREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAAM
                     CRARHIALASHDDATHAHVAQSHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDQSNRFTLPQAVRLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRKGNHIHIDHVWRQGKRVF"
     gene            10359..10916
                     /gene="phnN"
                     /locus_tag="ROH59_003849"
     CDS             10359..10916
                     /gene="phnN"
                     /locus_tag="ROH59_003849"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HDX4806279.1"
                     /translation="MTGKLIWLMGPSGSGKDSLLAELRQREQTQLLVAHRYITRDASA
                     GSENHIALSEREFFTRAGQNLLALSWHANGLYYGVGIEIDLWLHAGFDVVVNGSRAHL
                     PQARARYQSALLPICLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCLTLNN
                     DGSLRQSVDKLLTLIHQKEKHHACL"
     gene            10903..11337
                     /gene="phnO"
                     /locus_tag="ROH59_003850"
     CDS             10903..11337
                     /gene="phnO"
                     /locus_tag="ROH59_003850"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HDX4806280.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            11339..12097
                     /gene="phnP"
                     /locus_tag="ROH59_003851"
     CDS             11339..12097
                     /gene="phnP"
                     /locus_tag="ROH59_003851"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HDX4806281.1"
                     /translation="MSLILTLTGTGGAQGVPAWGCECAACARARRSPQYRRQPCSGVV
                     KFNDAITLIDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDTIPVYGPP
                     DEQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTLKFLRNNQPQVMVIDCSHPPREDAPRNHCDLNTVLALNQVIRSPRV
                     ILTHISHQFDAWLMENALPSGFEAGFDGMEIEVE"
     gene            complement(12125..12463)
                     /locus_tag="ROH59_003852"
     CDS             complement(12125..12463)
                     /locus_tag="ROH59_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806282.1"
                     /translation="MKRFPLFLLFTLFTLFTLFTVPAQADIIDDTIGNIQQAINDAYN
                     PDRGRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDERQRQLDQERQQLEDE
                     ERRMEDEYGR"
     gene            complement(12532..12981)
                     /gene="rpiB"
                     /locus_tag="ROH59_003853"
     CDS             complement(12532..12981)
                     /gene="rpiB"
                     /locus_tag="ROH59_003853"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional allose-6-phosphate
                     isomerase/ribose-5-phosphate isomerase RpiB"
                     /protein_id="HDX4806283.1"
                     /translation="MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYP
                     HYASQVALAVAGGEADGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDT
                     NVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQRRN"
     gene            13340..14230
                     /gene="alsR"
                     /locus_tag="ROH59_003854"
                     /gene_synonym="rpiR"
     CDS             13340..14230
                     /gene="alsR"
                     /locus_tag="ROH59_003854"
                     /gene_synonym="rpiR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418513.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="als operon DNA-binding transcriptional repressor
                     AlsR"
                     /protein_id="HDX4806284.1"
                     /translation="MSQSEFDSALPNGIGLAPYLRMKQEGMTENESRIVEWLLKPGNL
                     SCAPAIKDVAEALAVSEAMIVKVSKLLGFSGFRNLRSALEDYFSQSEQVLPSELAFDE
                     APQDVVNKVFNITLRTIMEGQSIVNVDEIHRAARFFYQARQRDLYGAGGSNAICADVQ
                     HKFLRIGVRCQAYPDAHIMMMSASLLQEGDVVLVVTHSGRTSDVKAAVELAKKNGAKI
                     ICITHSYHSPIAKLADYIICSPAPETPLLGRNASARILQLTLLDAFFVSVAQLNIEQA
                     NINMQKTGAIVDFFSPGALK"
     gene            14289..15224
                     /gene="alsB"
                     /locus_tag="ROH59_003855"
     CDS             14289..15224
                     /gene="alsB"
                     /locus_tag="ROH59_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose transporter substrate-binding protein"
                     /protein_id="HDX4806285.1"
                     /translation="MNKYLKYFSGTLVGLMLSTSAFAAAEYAVVLKTLSNPFWVDMKK
                     GIEDEAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVAR
                     AWKKGIYLVNLDEKIDMDNLKKAGGNVEGFVTTDNVAVGAKGASFIIDKLGAEGGEVA
                     IIEGKAGNASGEARRNGATETFKKASQIKLVASQPADWDRIKALDVATNVLQRNPNIK
                     AIYCANDTMAMGVAQAVANAGKTGKVLVVGTDGIPEARKMVEAGQMTATVAQNPADIG
                     ATGLKLMVDAEKSGKVIPLDKAPEFKLVDSILVTQ"
     gene            15352..16884
                     /gene="alsA"
                     /locus_tag="ROH59_003856"
     CDS             15352..16884
                     /gene="alsA"
                     /locus_tag="ROH59_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter ATP-binding protein
                     AlsA"
                     /protein_id="HDX4806286.1"
                     /translation="MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGK
                     STLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLY
                     IGRHLTKKICGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL
                     MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVM
                     KDGSSVCSGMVSDVSNDDIVRLMVGRELQNRFNAMKENVSNLAHDTVFEVRNVTSRDR
                     KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLD
                     AVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQ
                     RELLALKCHSVNQNITELSGGNQQKVLISKWLCCRPEVIIFDEPTRGIDVGAKAEIYK
                     VMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALP
                     QE"
     gene            16863..17843
                     /gene="alsC"
                     /locus_tag="ROH59_003857"
     CDS             16863..17843
                     /gene="alsC"
                     /locus_tag="ROH59_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter permease"
                     /protein_id="HDX4806287.1"
                     /translation="MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSS
                     EYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGI
                     DPFLAALIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYG
                     FSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGI
                     DVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGK
                     GRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK"
     gene            17854..18549
                     /gene="alsE"
                     /locus_tag="ROH59_003858"
     CDS             17854..18549
                     /gene="alsE"
                     /locus_tag="ROH59_003858"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allulose-6-phosphate 3-epimerase"
                     /protein_id="HDX4806288.1"
                     /translation="MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTL
                     SPFFVSQVKKLASKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEI
                     RRHGMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKVAELKAW
                     RERKDLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQIL
                     AAKSEVQPHAKTA"
     gene            18533..19462
                     /gene="alsK"
                     /locus_tag="ROH59_003859"
     CDS             18533..19462
                     /gene="alsK"
                     /locus_tag="ROH59_003859"
                     /EC_number="2.7.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allose kinase"
                     /protein_id="HDX4806289.1"
                     /translation="MQKQHNVVAGVDMGATHIRFCLRTAEGETLHCEKKRTAEVIAPD
                     LVSGIGEMIDEQLRRFNARCHGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKL
                     ENTLNCPVEFSRDVNLQLSWDVVENRLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGV
                     AGELGHIPLGDMTQHCACGNSGCLETNCSGMALRRWYEQQPRNYPLSDLFVHAENAPF
                     VQSLLENAARAIATSINLFDPDAVILGGGVMDMPAFPRETLIAMTQKYLRRPLPYQVV
                     RFIAASSSDFNGAQGAAILAHQRFLPQSCAKVP"
     gene            19735..>21719
                     /locus_tag="ROH59_003860"
     CDS             19735..>21719
                     /locus_tag="ROH59_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl/aryl-sulfatase"
                     /protein_id="HDX4806290.1"
                     /translation="MNNSRLFRLSRIVIAFTAASGMMINTAYATDEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKIYYRANDYKFDINAAAPETV
                     NPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
                     LDLYFQHRPQKPIVAVIYTHSHADHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISE
                     NVLAGNIMSRRALYSYGLLLPHNAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMI
                     IDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFYTLRGAKTRDTSKWT
                     EYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGDMIKLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMG
                     KRYVQALGGSARVINLAQEANKQGDYRWSAELLKQVIAANPGDQVAKNLQANNFEQLG
                     YQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMSVRLDSAKA
                     AGKNISLNFNMNNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
BASE COUNT         5212 a         5983 c         5780 g         4744 t
ORIGIN      
        1 aaaagaacga gtagagcatt aaccttatct taaataataa atggaggcaa aaagattatt
       61 ttctttttgc gtttcctttc aaatgaaaac gatcgtcatc taaaatcagc agtacccccg
      121 acaaactcag ggattttgtg tataattgcg gcctttttcg gcaatctgcc gttttttggc
      181 gcttttgccc tgctgacttt tgaggaaatc cacatgtcat taccacactg cccaaaatgc
      241 aactccgaat acacctacga agataacggc atgtacatct gcccggaatg tgcctacgaa
      301 tggaacgacg cagaacctgc acaggaaagc gacgagctga tcgttaaaga tgctaacggc
      361 aatctgctgg ctgacggcga cagcgttacc atcattaaag atctgaaagt gaaaggtagc
      421 tcttcgatgc tgaaaattgg caccaaagta aaaaacatcc gcctggttga aggcgaccat
      481 aacatcgatt gcaaaatcga cggttttggt ccgatgaaac tgaagtctga gtttgtgaaa
      541 aagaactgat tgtattgtga tcggtaggcc ggataaggcg ctcgcgccgc atccggcaac
      601 ggtggcgact gcctgatgcg acgctgaccg cgtcttatca ggcttccctc tcatctgtat
      661 aaatttcgaa ctacacttaa ctggcttctc ttaactgagg tcaccatcat gccgttaagt
      721 ccctacctct cttttgccgg taactgttcc gacgcgattg cctattatca acgtacgttg
      781 ggcgcggaac tgctctataa aatcagcttc ggcgaaatgc caaaatcaac gcaggacagc
      841 gccgagaact gcccttccgg aatgcaattt cccgataccg ccatcgccca cgccaatgtg
      901 cgcattgcag gaagcgacat catgatgagc gatgctatac cgtcaggaaa agccagctac
      961 tccggcttta cgctggtgct cgattctcaa caggtggaag aaggaaaacg ctggtttgat
     1021 aaccttgccg ccaacggaaa aatcgaaatg gcctggcagg aaacgttctg ggcgcatggc
     1081 tttggcaaag tcaccgataa atttggcgta ccgtggatga ttaatgtcat caaacaacag
     1141 ccaacgcaat aacccgccgg gaggcccgcc ctcccgcact gtcatcgaat tcccgttaac
     1201 tcttcatctg ttagtcactt ttaattaacc aaatcgtcac aataatccgc cacgatggag
     1261 ccactttttt agggaggctg catcatgcaa acgattatcc gtgtcgagaa gctcgccaaa
     1321 accttcaatc agcatcaggc gctgcacgcg gttgatctga acattcatca tggtgaaatg
     1381 gtggctctgc ttgggccgtc gggttccgga aaatccaccc ttttacgtca cttaagcggt
     1441 ttgattaccg gcgataaatc tgtcggtagc catatcgagc tgctgggccg cacagtccag
     1501 cgcgaaggcc gcctggcccg cgatatccgc aaaagccgcg ccaacaccgg ctacatcttt
     1561 caacaattca acctggtgaa tcgcctgagc gtactggaga acgtgctgat tggcgcgctc
     1621 ggcagcacgc cattctggcg aacctgtttt agctacttca cccgcgagca gaaacagcgc
     1681 gcgttacagg cgctgacccg cgttggcatg gtgcactttg cccatcaacg cgtttccaca
     1741 ctctccggcg gccagcaaca gcgtgtggcg attgcccgcg cgctgatgca gcaggcgaag
     1801 gtcattctcg ctgacgaacc catcgcctcg ctggacccgg aatcggcacg catcgtgatg
     1861 gacaccctgc gcgacatcaa ccagaacgac ggcattaccg tggtcgtcac gctgcatcag
     1921 gtggattacg ccctgcgcta ctgcgaacgc atcgtcgccc tgcgccaggg gcacgtcttc
     1981 tacgacggct gcagccaaca gtttgataac gaacgttttg accatctcta ccgcagcatt
     2041 aaccgcgtcg aagagaacgc gaaagctgcc tgacatcccc atcattgagg aaaacgaatg
     2101 aacgctaaga taattgcctc gctggccttc accagcatgt tcagcctcag caccctgtta
     2161 aatccggcat acgccgaaga gcaggaaaag gcgctgaatt tcggcattat ttcaacggaa
     2221 tcacagcaaa acctgaaacc gcaatggacg ccgttcttac aggatatgga gaagaagctg
     2281 ggcgtaaagg tcaacgcctt ctttgccccg gactacgcgg gcattatcca ggggatgcgc
     2341 ttcaataaag tggatatcgc ctggtacggc aacctgtcgg cgatggaagc ggtggatcgc
     2401 gccaacggtc aggtcttcgc ccagacggtc gcggcggatg gatcgccggg ttactggagc
     2461 gtgttgatcg tcaacaaaga tagcccgatc aacaacctga acgatctgct ggcgaagcgg
     2521 aaagatctca ccttcggcaa tggcgatcct aactctacct ccggcttcct cgtccccggt
     2581 tactacgtct tcgctaaaaa caatatctcc gccagcgact ttaagcgcac cgtcaacgcc
     2641 gggcatgaaa ccaacgccct cgccgtcgct aacaagcaag tggatgtcgc caccaacaac
     2701 accgaaaacc tcgacaagct gaaaacctcc gcgccggaga agctgaaaga actgaaggtg
     2761 atctggaaat caccgctgat ccctggcgat ccgatcgtct ggcgcaaaaa tctttccgaa
     2821 accactaaag acaagatcta cgacttcttt atgaattacg gcaaaacgcc ggaagagaaa
     2881 gcggtgctgg agcgcctggg ctgggcgccg ttccgcgcct ccagcgactt gcaactggtg
     2941 ccgattcgcc agctcgcact gtttaaagag atgcaaagcg tgaaggacaa caaagggctg
     3001 aacgaacagg acaagctggc aaaaaccacc gccattcagg cgcaactgga tgatttggac
     3061 cgcctgaaca acgcgttaag cgcaatgagt tcggtgagta aagcggtgca gtaaatcgta
     3121 ggtcggataa gacgcccggc gtcgcatccg acaatgtgca gacgttgatg ccggatgcgg
     3181 tgcaagcacc ttatccggcc tacagaccgg agccaaacat gcaaaccatc accatcgccc
     3241 cacccaagcg cagctggttc tcgcttctga gctgggccgt tgttatcgcc gtgctggtcg
     3301 tctcgtggca gggcgcggaa atggccccgc ttacgctgat taaagatggc ggcaacatgg
     3361 cgacgttcgc cgccgacttc ttcccgcccg atttcagcca gtggcaggat tacctcaccg
     3421 aaatggccgt cacgctgcaa atcgccgtct ggggcaccgc gctggcggtg gttctctcca
     3481 tccccttcgg cctgatgagc gctgaaaacc tggtaccgtg gtgggtctac caacctgtac
     3541 gccgcctgat ggacgcctgc cgcgccatta acgaaatggt cttcgccatg ctgttcgtgg
     3601 tcgccgtcgg cctcggcccg ttcgctggcg tgctggcgct gtttatccac accaccggcg
     3661 tgctctccaa gctgctttcc gaagcggtgg aagcgatcga acccggcccg gtggagggca
     3721 ttcgcgccac cggtgccaac aagctggaag agatccttta cggcgtacta ccgcaggtca
     3781 tgccgctgct gatttcctac tctctctatc gcttcgaatc caacgtccgc tcggcgaccg
     3841 tcgtcggtat ggttggcgcg ggcgggatcg gcgtcacgct gtgggaagcg attcgcggtt
     3901 tccagttcca gcaaacctgc gccctgatgg tgctcatcat cgtcacggtc agcctgctgg
     3961 atttcctctc tcaacggttg cgtaagcact ttatctgata agcgaggcat tgatatctat
     4021 gcacttgtct acacatccga ccagctaccc aacacgctat caggagatag ccgcaaaact
     4081 tgagcaggag cttcgtcaac actaccgctg cggcgactat cttcccgccg agcagcaact
     4141 ggcggcgcgc tttgaggtga accgccacac cctgcgccgc gccatcgacc aactggtgga
     4201 aaaaggctgg gtacagcgcc gtcagggcgt cggcgtactg gtgctgatgc gcccgttcga
     4261 ttacccgctc aacgcccagg cgcgttttag ccagaacctg ctggaccagg gcagccatcc
     4321 caccagcgaa aaattgctat cggtgctgcg ccccgcctcc ggtcacgtcg ctgacgcgct
     4381 ggggataacc gagggggaga acgtcatcca cctgcgcacc ctgcgtcggg tcaacggcgt
     4441 cgcgctctgt ttaatcgacc actactttgc ggacctcacc ctctggccga cgctgcaacg
     4501 tttcgacagc ggttcgctgc acgattttct gcgcgagcaa acggggatta cgctacgacg
     4561 cagtcagacg cggatcagcg cccgtcgcgc ccaggccaaa gagtgccagc gtcttgaaat
     4621 cccgaatctg tcgccgctgc tgtgcgtgcg cacccttaac caccgtgacg gtgaaagcag
     4681 cccggcggag tactccgtca gcctgacgcg cgccgacatg attgaattca ctatggagca
     4741 ctgaatgcac gcagataccg cgacccgcca gcactggatg tccgtgctgg cgcacagcca
     4801 accggctgaa ctggcagccc gcctgaacgc gctgaacatc aacgccgatt atgaggtgat
     4861 ccgcgccgct gaaactggcc tggtgcagat tcaggcgcga atgggcggca ccggcgaacg
     4921 cttttttgct ggcgacgcca cgctcacccg cgccgccgtg cgtctgactg acggcacgct
     4981 cggctatagc tgggtgctgg ggcgcgacaa acagcacgcc gaacgttgtg cgctgattga
     5041 tgcgctgatg cagcaaaacc gccactttca aaacttatca gaaaccctta tcgccccgct
     5101 ggacgctgac cgtatggcac gcattgccgc gcgccaggcc gaagtgaacg ccagccgggt
     5161 cgacttcttt acgatggttc gcggagacaa cgcatgaccc tggaaaccgc ttttatgctt
     5221 cccgtgcagg atgcccagca cagttttcgt cgcctgttaa aggccatgag cgagccgggc
     5281 gtgattgtcg ccctgcatca gctcaagcgc ggctggcagc cgctgaatat cgccaccacc
     5341 agcgtgctgc tgacgctggc cgataacgac acgccggtgt ggcttgccgc gccattgagc
     5401 aacgatatcg tcaatcagag cctgcgtttt cataccaacg cgtcgctggt taatcagccg
     5461 gaacaggcga ccttcgcggt aacagatgag gcgatctcca gcgagcagct caacgccctt
     5521 tccaccggca ctgccgttgc accagaagcg ggcgcaacgc tgattttaca ggtcaccagc
     5581 ctgagcggcg ggcgtatgtt gcgcctcacc ggcgcaggta ttgccgaaga acggatgatc
     5641 gccccgcaac tgccaaagtg cattcttcat gaacttaccg agcgcccgca cccgttcccg
     5701 ctcggcatcg acctgatcct gacctgcggc gagcgcctgc tggctattcc gcgaaccact
     5761 catgtggagg tgtgctgatg tacgttgccg tgaaaggggg cgaaaaggcg atcgacgccg
     5821 cccacgccct gcaagagagc cgacgccggg gcgatactga tttgcctgaa ctgagcgtcg
     5881 cccagattga acagcagctt aacctcgcgg tagatcgcgt gatgaccgaa ggcggtattg
     5941 ccgaccgcga gctggccgcg ctggcgctga aacaggccag cggcgataac gtcgaagcga
     6001 tttttctgtt gcgcgcctac cgcaccacgc tggcgaagct ggcggtcagt gagccgctcg
     6061 acaccaccgg gatgcgtctc gaacggcgta tttcagcaat ttataaagac attcccggcg
     6121 gccaactgct tggccccacc tacgactaca cccatcgcct gctcgatttc accctgctgg
     6181 caaacggcga aacgccaacg ctgaccaccg ctgacagcga acagcaaccg tcgccacacg
     6241 tcttcagcct gctggcgcgt caggggctgg cgaagtttga agaagatagc ggcgcacaac
     6301 cggacgacat cacccgcacg ccgccggttt atccctgttc gcgttcttcc cgtctacaac
     6361 aattaatgcg cggtgacgaa ggctatttgt tggcgctggc ctactccacc caacgcggtt
     6421 acgggcgcaa tcacccgttc gcaggcgaaa ttcgcagtgg ctatatcgat atatttattg
     6481 tgccggaaga gctgggattt gcggtgaacg tcggcgaatt gttgatgacc gagtgtgaaa
     6541 tggtcaacgg ttttatcgac ccgccggatg aaccaccgca ttttacacgc ggctatgggc
     6601 tggtgttcgg catgagcgag cgcaaagcaa tggcgatggc gctggttgac cgtgcgttgc
     6661 aggcaccgga atacggcgag cacgcaacag gtccggcaca ggatgaagag ttcgtgctgg
     6721 cccatgccga caacgtcgaa gccgcaggct ttgtttcgca tctcaaactc ccgcactacg
     6781 tcgatttcca ggccgaactg gagctactca aacgtctgca acaggagcag aaccatggct
     6841 aatctgagcg gctacaactt tgcttacctc gacgagcaga ccaaacgcat gatccgccgc
     6901 gctatcttaa aagcggtggc aatccccggt tatcaggtgc cgtttggcgg acgcgagatg
     6961 ccgatgccct acggctgggg aaccggcggc attcagctca ccgccagcgt gattggcgaa
     7021 agcgacgtgt tgaaggtgat tgaccagggc gcagacgaca ccaccaacgc cgtgtcgatt
     7081 cgtaacttct ttaagcgcgt gaccggggtg aacaccaccg agcgcacgga cgatgcgaca
     7141 cttatccaga cgcgtcaccg catacccgaa acgccgctga ccgaagatca gatagttatc
     7201 ttccaggtgc cgatccccga accgctgcgc tttattgagc cgcgtgagac ggaaacgcgc
     7261 accatgcacg cgctggagga gtacggcgtg atgcaggtga agctgtatga agatatcgcc
     7321 cgcttcggtc atatcgccac cacctacgcc tatccggtga aggtgaacgg gcgctacgtg
     7381 atggacccgt cgccgatccc gaaattcgat aacccgaaaa tggacatgat gcccgccctg
     7441 caactgtttg gcgcggggcg cgagaagcgc atctatgccg tgccaccgtt tacccgcgtg
     7501 gaaagcctcg atttcgatga tcatccgttc accgtccagc agtgggatga accatgcgcc
     7561 atctgcggat cgacccacag ctatcttgat gaagtggtgc tggatgacgc cggaaaccgc
     7621 atgtttgtct gctccgatac cgattattgc cgccaacaga gcgaggccaa aagccaatga
     7681 atcaaccgtt actttcggtc aataacctga cccaccttta tgccccgggc aaaggcttca
     7741 gcgatgtctc ttttgattta tggccgggag aagttctggg cattgttggg gagtccggtt
     7801 ccgggaagac cacgctactg aaatcaattt ccgcccgcct gacaccacag caaggggaaa
     7861 ttcgctacga gaaccgttcg ctgtacgcga tgagcgaggc cgaccgccgt cgcctgctgc
     7921 gcaccgaatg gggtgtggtg catcagcatc cgcttgacgg cctgcgccgc caggtgtcgg
     7981 caggcggcaa tatcggcgaa cggttgatgg caaccggagc gcgtcattac ggcgatattc
     8041 gcgccaccgc gcagaaatgg ctggaagagg tggagattcc cgccaaccgg atcgacgacc
     8101 tgccgaccac cttttccggc ggcatgcagc aacgtttgca gattgcccgc aacctggtga
     8161 cgcatccgaa gctggtgttt atggatgaac ccactggcgg gctggatgtg tcggtacagg
     8221 cgcgcctgct ggacctgctc cgcggtctgg tgatggagct taacctggcg gtagtgattg
     8281 tcacccacga tttaggcgtc gcccgtctgc tggcggaccg tttgctggta atgaagcaag
     8341 ggaaagtggt ggagagtggg ttaaccgacc gcgtgctcga cgacccgcac catccgtata
     8401 cccagttgct ggtgtcatcg gttttgcaga attgagctgg tgccggatgc ggcgtaaacg
     8461 ccttatccgg cctacaaatg cgctccccgt aggtcggata agacgcatca gcgtcgcatc
     8521 cgacacccga accacgaggc gaaaaatgat taacgtacaa aacgtcagta aaaccttcat
     8581 cctgcaccag caaaacggcg tgcgcctgcc tgtattacaa ggcgcctcac tcaccgtcaa
     8641 cgccggcgaa tgcgtggtac tccacggcca ttccggcagt ggaaaatcaa ctctgctacg
     8701 ctcgctgtat gccaactatc tacccgacga agggcaaatc cagatcaaac acggtgatga
     8761 atgggtcgac ctggtcaccg cgccagcgcg caaagtggtg gagatccgca aaaccactgt
     8821 cggctgggta agccagtttc tgcgcgtcat cccacgtatt tcggcactgg aagtggtgat
     8881 gcagccgctg ctcgataccg gcgtaccgcg tgaagcctgc gccgctaaag ccgcgcgtct
     8941 cctcacccgc ctgaacgtgc ctgaacgcct gtggcacctt gcgccatcga ccttctccgg
     9001 tggcgaacag cagcgtgtca acatcgcccg tggctttatc gtcgactacc ccattctgct
     9061 gctcgacgaa cctaccgcct cgctggacgc taaaaacagc gccgccgtag tggaactgat
     9121 ccgcgaagcc aaagcccgcg gcgcggccat cgtcggtatc ttccatgacg aaaccgtacg
     9181 cgagcaagtc gccgaccgcc tgcacccaat gggagtctct tcatgattat caataacgtc
     9241 aaactggtgc tggaaaacga ggtggtacac ggttctctgg agatgcagga cggcaaaatc
     9301 cgcgcctttg ccgaaagcca gagtcacctg tcagaagcaa tggacggcga aggcggctgg
     9361 ctgctaccgg ggctgattga gctgcatacc gataatctgg ataaattctt caccccgcgc
     9421 ccgaaagttg actggcctgc ccactcggcg atgagcagcc acgacgcgct gatggtggcg
     9481 agcggcatca ccaccgtgct ggacgccgtg gcgattggtg atgtacgcga cggcggcgat
     9541 cggctggaga atctggagaa gatgatcaac gccatcgaag agacgcagaa acgcggcgtc
     9601 aaccgtgccg agcaccgtct gcacctacgc tgcgaactgc cgcatcacac cacgctgccg
     9661 ctgtttgaaa aactggtcga gcgagaaccc gtgacgctgg tgtcgctgat ggatcactca
     9721 ccgggccagc gccagttcgc caaccgcgaa aaatatcgtg aatattatca gggcaaatac
     9781 tcgctcaccg atgcgcagat gcaacagtac gaagaggagc aactggcgct cgccgcacgc
     9841 tggtcacagc cgaatcgcga atccatcgcc gcaatgtgcc gcgcgcgaca cattgcgctc
     9901 gccagccacg atgacgccac gcacgcccac gtagcccaat cccatcagct tggcagcgtg
     9961 atcgccgaat ttcctaccac attcgaagcg gcagaagcct cgcgcaagca cggcatgaac
    10021 gtactgatgg gcgcgccgaa tatcgtgcgc ggcggttcgc actccggcaa cgtggcggcc
    10081 agtgaactgg cgcagcttgg cctgctggat atcctctctt ccgactacta ccccgccagc
    10141 ctgctggatg cggcgtttcg cgtggccgat gaccagagca accgctttac gctaccgcag
    10201 gcggtgaggc tggtgaccaa aaacccggcc caggcactga atctccagga tcgcggggtg
    10261 attggcgagg gcaaacgcgc cgacctggtg ctggcgcatc gcaagggcaa tcacattcat
    10321 attgaccacg tctggcgtca gggtaaaagg gtgttctgat gacgggaaaa ctgatttggt
    10381 taatgggtcc gtccggctcc gggaaagaca gcctgctggc ggaactccgc cagcgggaac
    10441 aaacccagct actggtagcg catcgctaca tcacgcgtga tgccagcgcc ggaagtgaaa
    10501 atcatatcgc cttaagcgag cgggagtttt ttacccgcgc ggggcaaaat ctgttggcct
    10561 tgagctggca tgctaatggt ttgtattacg gtgtcggcat tgagatcgac ctctggctgc
    10621 acgccggatt cgacgtcgtg gttaacggct cacgcgccca cctgccgcag gcgcgggcac
    10681 gttatcaatc ggcactgctg cccatctgtt tacaggtttc gccggagatc ctgcgccagc
    10741 gcctggaaaa ccgtggccgc gaaaacgcca gtgaaattaa cgcccggctg gcgcgcgccg
    10801 cccgctatac tcctcaggat tgtcttacgc tcaataatga cggcagcctg cgccagtcgg
    10861 tcgacaagct gctgacgctg attcatcaga aggagaaaca ccatgcctgc ttgtgagctt
    10921 cgcccggcta cgcagtacga caccgacgca gtttacgcgc tgatttgtga gctaaaacag
    10981 gcggagtttg accaccacgc gtttcgcgtg gggtttaacg ccaatctgcg cgatccgaac
    11041 atgcgctacc atctggcgct gctggatggc gaagttgtcg gcatgatcgg cctgcatttg
    11101 cagtttcatc tgcatcatgt caactggatc ggcgaaattc aggagttggt ggtgatgccg
    11161 caggcgcgcg gcctgaacgt cggtagcaag ttgctggcgt gggcagaaga agaagcccgc
    11221 caggccgggg ccgaaatgac cgagctttcg accaacgtga agcgccacga cgcgcaccgt
    11281 ttctatctgc gcgaaggcta cgagcagagc catttccgct tcaccaaagc gctgtaacat
    11341 gagcctgatc ctcacgctca ccggcactgg cggcgcacag ggcgttcccg catggggctg
    11401 tgagtgcgcg gcctgcgcca gagcgcggcg ctcaccgcag tatcgccgcc agccatgcag
    11461 cggcgtcgtg aagtttaacg acgcgatcac cctgatcgac gccgggctgc acgatctcgc
    11521 cgatcgctgg tcgcccggat cgttccagca gtttttgctg acgcactacc atatggatca
    11581 cgtgcagggg ctgtttccgc tgcgctgggg cgtgggcgac acaatcccgg tctacggtcc
    11641 accggatgag cagggctgcg acgatctgtt taaacatccg ggcctgcttg atttcagcca
    11701 cacggtggag ccgtttgtgg tgtttgattt gcaggggttg caggtcacgc cgctgccgct
    11761 taaccattcg aaactcactt tcggctattt actggaaacg gcgcacagcc gggtggcgtg
    11821 gctatctgac accgcaggcc tgccggaaaa aacgctgaaa tttttacgca ataatcagcc
    11881 gcaggtaatg gtgattgatt gcagccaccc gccgcgcgag gatgcaccgc gtaatcactg
    11941 tgatttaaat accgtgcttg cgctgaatca ggttatccgc tcgccacggg tgattctgac
    12001 ccatatcagc caccagtttg atgcgtggct gatggaaaat gcactgccgt cggggtttga
    12061 ggcggggttt gatgggatgg agattgaggt ggagtgaggg aaaatacccg cgccggcccc
    12121 tacctcaacg cccatactca tcttccattc tccgctcttc atcttccagt tgctgacgct
    12181 cctgatcaag ctggcgctgg cgttcgtcca gctgcctgcg gcgatcttca aactggcggc
    12241 ggcggtcatc atattgtctg cgccgatcgt cgctcacttc acgctgccag ccgtcgtcgc
    12301 gcgaatcttc atagtctcgc ccacggtcag ggttataagc gtcgttaatc gcctgctgaa
    12361 tattgccaat ggtgtcatcg ataatatcgg cctgggccgg aacggtgaac agcgtgaaca
    12421 gcgtgaacag cgtgaataaa agaaatagcg gaaagcgttt cattagccaa cctcaaaaag
    12481 aaactctatc cacattagtc attactcatc catgcaagta gtggatgaat ctcaatttct
    12541 ccgctgctct attgccgtaa tcgcctccac gcgttgttga tgacgaccgc cttcgtactg
    12601 tgcgcccagc cacgcatcga caatcatttt tgccagttcg aggccaacta ctcgtgaacc
    12661 aaaagccagc acgttggtgt cgttatgctg ccgcgaaagt tgcgcggaat aaggttcgct
    12721 acaaacgacc gcgcgaattc cggcaaactt gttcgccgct atcgaaatac cgacgccagt
    12781 gccacaaatc aaaatcccgc catcagcctc tccgccagca acggccagtg cgacttgact
    12841 ggcgtaatgc ggataatcag tacgctctga cgaccaggtt cctttatcaa tcacttcaac
    12901 gccacgctca actaaatgtg ccactatttc atgttttaaa atgaaaccga catgatcaca
    12961 gccaaatgca atctttttca ttcatcttcc ccgctcgcgc aaaacttcac aataaaaaaa
    13021 catttgtgat ttaaatgaat taaaaacacc caaaatcgat gaaatcagcc ttcccgatct
    13081 gttttacaga gttacatctg gcagcgcaat agcgttaaag acactcacta tccggcaaca
    13141 tctatcatct aataaaccag aaaaacaaat aacatcatgt ttttaaagtg attaaatgaa
    13201 ataaaatttt aagccactct ccattattca caataaaaca aactttataa attttatttt
    13261 tttgtgaagt tgccagcatc ttttctgttc ttgctgtggt gatatagtgg cgtcttcaat
    13321 tcaaggacaa gagaacgtga tgagccagtc agagtttgat tcagcgcttc cgaacggtat
    13381 cgggttagcg ccttacctgc gaatgaagca ggaaggaatg acagaaaacg aaagccgcat
    13441 cgtggagtgg ttactcaaac ccggtaacct gagttgtgca cccgcaatta aagatgtcgc
    13501 agaagctctg gcggtatctg aagcgatgat cgttaaggta tcaaagctgc tggggtttag
    13561 cggctttcgt aacttacgca gtgcgctgga agattatttt tctcagtcag aacaagtatt
    13621 gccgtccgag ttggcttttg atgaagcgcc gcaggatgtg gtgaataagg tatttaacat
    13681 cactttacgc accattatgg aaggtcagtc gatcgtcaac gttgatgaga tccaccgtgc
    13741 cgcccgcttt ttctatcagg ccagacagcg ggatttgtac ggtgccggag gatcaaatgc
    13801 aatctgtgct gatgtacagc acaagttttt acgcattggc gtacgctgcc aggcctatcc
    13861 ggacgctcac atcatgatga tgtctgcttc gttgttacag gaaggagatg tggtgctggt
    13921 ggtgacccat tccgggcgaa ccagtgatgt aaaagcagct gtagaactgg caaaaaagaa
    13981 cggggcaaag attatttgta taacgcatag ctaccattca ccgatagcga agctggccga
    14041 ttatattatt tgctcaccgg ccccggaaac accgttatta ggtcgtaatg cctcggcaag
    14101 aatattacaa ctaactttgc tggacgcgtt ttttgtctct gtcgcccagc tcaacattga
    14161 acaagctaat attaatatgc aaaaaaccgg cgcaattgtt gatttcttct caccaggcgc
    14221 gctgaaataa gaaaaaggta attccgccat cgcggagtta cctatcccct taccgtgaga
    14281 acatgattat gaataaatat ctgaaatatt tcagcggcac actcgtgggc ttaatgttgt
    14341 caaccagcgc ttttgctgcc gccgaatatg ccgtcgtatt gaaaacactc tccaacccat
    14401 tttgggtaga tatgaaaaaa ggcattgaag atgaagcaaa aacgctgggc gtcagcgttg
    14461 atatttttgc ctctccttca gaaggcgatt ttcaatctca attgcagtta tttgaagatc
    14521 tcagtaataa aaattacaaa ggtatcgcct tcgcaccatt atcctcagtg aacctggtca
    14581 tgcctgtcgc ccgcgcatgg aaaaaaggca tttatctggt caatctcgat gaaaaaatcg
    14641 acatggataa tctgaaaaaa gcaggcggta atgtggaagg ttttgtcacc accgataacg
    14701 ttgccgtcgg ggcgaaaggc gcgtcattca ttattgacaa gctgggtgcc gaagggggtg
    14761 aagttgcaat tattgaaggt aaagccggta acgcctccgg tgaagcgcgt cgtaatggtg
    14821 ccaccgaaac cttcaaaaaa gcaagccaga tcaagcttgt cgccagccag cctgccgact
    14881 gggaccgcat taaagcactg gatgtcgcca ctaacgtgtt gcaacgtaat ccgaatatta
    14941 aagcgatcta ttgcgcgaat gacacgatgg caatgggtgt tgctcaggct gtcgcaaacg
    15001 ccggaaaaac gggaaaagtg ctggtcgtcg gtacagatgg cattccggaa gcccgcaaaa
    15061 tggtggaagc cggacaaatg accgcgacgg ttgcccagaa cccggcggat atcggcgcta
    15121 cgggtctaaa gctgatggtt gacgctgaaa aatccggcaa ggttatcccg ctggataaag
    15181 caccggaatt taaactggtc gattcaatcc tggtcactca ataaaactaa atgatgccgg
    15241 atagtgatgc taatgaagtg tcttatccgg ccaacaaaat aacctgaacg tagacctgat
    15301 aagtgtagcc catcaggcaa taatacgata tttcgtgcag agaggttatt tatggccacg
    15361 ccatatatat cgatggcggg gatcggcaag tcctttggtc cggttcacgc attaaagtcg
    15421 gttaatttaa cggtttatcc tggtgaaata catgcattac taggagaaaa tggcgcgggt
    15481 aaatccacgc taatgaaagt gttatccgga atacatgagc caaccaaagg caccattacc
    15541 attaataaca ttaactataa caaactggat cataaattag cggcacaact cggtatcggg
    15601 attatttatc aggaactcag cgttattgat gaattaaccg tactggaaaa tttatatatt
    15661 ggtcgtcatc tgacgaaaaa aatctgcggt gtcaatatta tcgactggcg agaaatgcgt
    15721 gtccgcgccg caatgatgtt attacgcgtg ggcttgaaag ttgatttaga tgagaaagtg
    15781 gcgaacttat ctatcagcca caagcagatg ctggaaattg ccaaaacgct gatgctcgac
    15841 gccaaagtca tcatcatgga tgaacccacc tcctcactca ccaataaaga ggtggactat
    15901 ctgtttctga tcatgaatca gttgcgtaag gagggtacgg ctatcgtcta tatctcgcat
    15961 aaattggcgg aaattcgccg tatttgcgac cgctatacgg tgatgaaaga cggcagcagc
    16021 gtttgcagcg gcatggtgag cgatgtgtca aatgacgata tcgtccgtct gatggtaggc
    16081 cgcgaactgc aaaaccgttt taacgcgatg aaggagaatg tcagcaacct tgcgcacgat
    16141 acggtttttg aggtgcgcaa cgtcaccagc cgtgacagaa aaaaggtccg ggatatctca
    16201 tttagcgtct gccggggaga aatattaggc tttgccggac tggtcggttc cggacgtact
    16261 gaactgatga actgcctgtt tggcgttgat aaacgcgctg gcggagaaat ccgtcttaat
    16321 ggcaaagata tctctccacg ttctcccctg gatgccgtga aaaaagggat ggcttacatc
    16381 actgaaagcc gccgggataa cggctttttc cccaactttt ctatcgctca gaacatggct
    16441 atcagccgca gtctgaaaga cggcggctat aaaggcgcga tggggttgtt tcatgaagtt
    16501 gacgagcaac gtaccgctga aaatcaacgc gaactgctgg cgctgaaatg tcattcggta
    16561 aaccagaaca tcactgaact ctccggcggt aaccagcaga aagtcctgat ctccaaatgg
    16621 ctgtgctgtc gcccggaagt gatcattttc gatgaaccta cccgtggcat cgacgttggc
    16681 gcgaaagccg aaatttacaa agtgatgcgc caactggcgg acgacggaaa agtcatcctg
    16741 atggtgtcat ctgaactacc tgaaattatc accgtctgcg accgcatcgc cgtgttctgc
    16801 gaaggacgac tgacgcaaat cctgacgaat cgcgatgaca tgagcgaaga ggagattatg
    16861 gcatgggctt taccacaaga gtaaaaagcg aagcgagcga gaagaaaccg ttcaactttg
    16921 cgctgttctg ggataaatac ggtacttttt ttatcctggc gatcatcgtc gccatttttg
    16981 gttcgctgtc gtcagaatat tttctgacca ccaataatat tacccagatt tttgtgcaaa
    17041 gctccgtgac ggtactgatc ggcatggggg aattcttcgc tatcctggtc gccggtatcg
    17101 acctttcggt tggcgcgatt ctggcgcttt ccggtatggt gaccgctaaa ctgatgttgg
    17161 caggtattga tccgtttctc gcggcgctaa ttggcggtgt actggttggc ggcgcactgg
    17221 gggcgatcaa cggctgcctg gtcaactgga cgggactaca cccgttcatt atcacccttg
    17281 gcaccaacgc tattttccgt gggatcacgc tggtgatctc cgatgccaac tcggtatacg
    17341 gcttctcatt tgacttcgtg aacttctttg ccgccagcgt aattgggata cctgtccccg
    17401 ttatcttctc gctaattgtc gcgctcatcc tttggtttct gacaacgcgt atgcggctcg
    17461 ggcgcaacat ctacgcactg ggcggcaaca aaaactcggc gttctattcc gggattgacg
    17521 tgaaattcca catcctggtg gtgtttatca tctccggtgt ttgtgcaggt ctggcaggcg
    17581 tcgtctcaac tgcacgactc ggtgccgcag aaccgcttgc cggtatgggt tttgaaacct
    17641 atgccattgc cagcgccatc attggcggca ccagtttctt cggcggcaag gggcgcattt
    17701 tctctgtggt gattggcggg ttgatcatcg gcaccatcaa caacggtctg aatattttgc
    17761 aggtacaaac ctattaccaa ctggtggtga tgggcggatt aattatcgcg gctgtcgccc
    17821 ttgaccgtct tatcagtaag taaggaattg aacatgaaaa tctccccctc gttaatgtgt
    17881 atggatctgc tgaaatttaa agaacagatc gaatttatcg acagccatgc cgattacttt
    17941 cacatcgata tcatggacgg ccactttgtg ccgaatctga cgctctcacc gttcttcgta
    18001 agccaggtaa aaaaactggc gagtaaaccg ctcgactgcc atctgatggt aacgcgtccg
    18061 caggattaca ttgctcaact ggcacgtgcg ggagctgatt tcatcacttt gcatccggaa
    18121 actatcaacg gtcaggcatt ccgcctgatt gatgaaatcc gccgtcatgg catgaaagtg
    18181 gggctgattc ttaatccgga aacgccggtt gaggccatga aatactatat ccataaggct
    18241 gataaaatta cggtcatgac tgtcgatccc ggttttgccg gacaaccctt cattcctgaa
    18301 atgctggata aagttgccga actgaaggca tggcgtgaac gaaaagatct ggagtacgaa
    18361 attgaggtgg acggttcctg caaccaggca acttacgaaa aactaatggc ggcaggggcg
    18421 gatgtcttta tcgtcggcac ttccggcctg tttaatcatg cggaaaatat cgacgaagca
    18481 tggagaatta tgaccgcgca gattctggct gcaaaaagcg aggtacagcc tcatgcaaaa
    18541 acagcataac gtcgtagcgg gcgtggatat gggggcaacg catatccgct tttgtctgcg
    18601 gacagcagaa ggtgaaacgc tacactgcga aaaaaagcgg accgcagaag ttattgctcc
    18661 cgacctggtg tcgggtatcg gcgaaatgat tgacgagcaa ctcaggcgct ttaacgctcg
    18721 ctgtcatggt ctggtgatgg gatttccggc gctggtcagt aaagataaac gcaccattat
    18781 ttctacgcct aacctgccgt taacagcggc agatttatat gatctcgccg ataagctcga
    18841 aaatacgctg aattgtccgg ttgagttttc ccgcgacgtt aacctgcaac tttcctggga
    18901 cgtagtagaa aaccgcctta cgcaacaact ggttctggcg gcctatctcg gtacggggat
    18961 ggggttcgca gtgtggatga acggtgcgcc gtggacgggt gcacacggtg tggcaggcga
    19021 actgggccat atccccctgg gagatatgac ccaacactgc gcgtgtggca attctgggtg
    19081 cctggaaacc aattgctctg gaatggcgct aagacgctgg tacgaacaac agccccgaaa
    19141 ttacccattg agcgatcttt tcgtccatgc ggaaaacgcc cctttcgtcc agagtctgct
    19201 tgaaaacgcg gcacgagcca ttgccaccag cattaatctg ttcgatcccg atgcggtgat
    19261 tctgggcggt ggcgtgatgg atatgcccgc cttcccacgc gagactctca ttgccatgac
    19321 ccaaaagtac ctgcgccgtc cactgccgta tcaggtcgtg cgctttattg ccgcctcatc
    19381 ttctgacttt aatggcgctc agggtgcagc aatattggcg catcaacgtt ttttgccaca
    19441 gtcctgtgct aaagtcccat gagtaaagcg ttggcacagt agcgcaatgt cccgctgtgc
    19501 caacgacagg tacaatatat ataataatta cataaaacag cccatattat tcccagcaat
    19561 gatagttcta ctgtaatttt ccctcttcag cacaaatgcc taataaaatg gctcgttccg
    19621 ctcacacttc cacttattaa agtcgcaaat tcccaattat gataacgcca gctttaaatg
    19681 acgtattttg catggattac atatttacga cataaatgat aaatggagat ttatatgaat
    19741 aactctcggt tattccgttt gagcaggatt gttattgcgt tcactgccgc cagcggcatg
    19801 atgataaata ccgcttacgc aacagatgag gcgaaagccg ccactcaata tacccaacag
    19861 gttaatcaga attacgccaa atcattaccg tttagcgatc gccaggattt tgacgatgct
    19921 cagcgtggat ttatcgctcc gctgctggat gaaggtattc tgcgtgatgc gaacggtaaa
    19981 atttactacc gcgcgaatga ttacaaattt gatattaatg ccgctgcgcc ggaaaccgta
    20041 aaccccagcc tgtggcgtca gtcgcagatc aacggcattt caggcctgtt caaagtcacc
    20101 gataaaatgt atcaggtgcg cggccaggat atctctaaca ttacgttcgt tgagggcgag
    20161 aaaggcatta ttgttattga cccactggtg acgccacctg ccgcaaaagc cgcacttgac
    20221 ctttacttcc agcatcgtcc gcaaaaaccg attgttgccg ttatctacac tcacagccac
    20281 gccgaccact acggcggcgt gaaaggtatt atctctgaag ccgatgttaa atccggcaaa
    20341 gttcaggtga ttgctccagc tggctttatg gacgaagcca tcagcgaaaa cgtgctggcg
    20401 ggtaacatca tgagccgccg tgcgctctac tcttacggtc tgttactgcc gcacaacgcg
    20461 caaggcaacg tgggcaacgg cctcggcgtg acgctggcaa cgggcgaccc gagcattatt
    20521 gcaccgacta aaactatcgt cagaactggc gagaagatga ttatcgacgg cctggagttt
    20581 gacttcctga tgaccccagg tagcgaagcg ccagcggaaa tgcacttcta tattccggcc
    20641 ctgaaagccc tgtgtaccgc cgagaatgcc acgcataccc tgcacaactt ctacaccctg
    20701 cgcggcgcga aaacccgcga caccagcaag tggaccgagt atctgaacga aacattggat
    20761 atgtggggta acgacgcgga agtactgttt atgccgcaca cctggccggt ctggggcaat
    20821 aagcatatca atgattatat tggtaaatat cgcgatacta tcaagtacat tcacgaccag
    20881 accctgcacc tggcgaacca gggctacacc atgaatgaaa tcggcgacat gattaagctg
    20941 ccgcctgcgc ttgccaataa ctgggccagc cgcggctatt acggttctgt cagccacaac
    21001 gcccgcgcgg tatataactt ctatcttggc tattacgacg gtaacccggc taacctgcat
    21061 ccgtatggtc aggtggagat gggtaaacgt tacgtgcagg cgctgggcgg ttctgcccgc
    21121 gtcatcaacc tggcgcaaga agcgaacaag caaggtgatt atcgctggtc ggcagaactg
    21181 ctgaaacagg tgattgccgc caacccgggt gaccaggtcg cgaagaatct gcaagcgaat
    21241 aactttgaac agctgggcta tcaggccgag tccgccacat ggcgcggttt ctacctgacc
    21301 ggcgcgaaag agctgcgcga aggggtgcat aagttcagcc acggcaccac cggttccccg
    21361 gacaccattc gtgggatgtc ggtcgaaatg ctgttcgact ttatgtccgt tcgcctcgat
    21421 agcgcgaaag ccgcgggtaa aaatatcagc ctgaacttca atatgaacaa cggcgataac
    21481 ctcaacctga cgctgaacga tagcgtgctt aactaccgta aaacactgca accgcaagct
    21541 gacgcctctt tctacatcag ccgtgaagat ctgcacgccg tgctgaccgg acaggcaaaa
    21601 atggctgatc tggtgaaagc gaagaaagcc aaaattattg gcaatggtgc gaaactggaa
    21661 gaaattatcg cctgtctgga taatttcgat ttgtgggtga atatcgtaac cccaaatta
//
LOCUS       DAPOXO010000084        21710 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.084, whole genome shotgun sequence.
ACCESSION   DAPOXO010000084 DAPOXO010000000
VERSION     DAPOXO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21710
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.084"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            320..1177
                     /gene="focA"
                     /locus_tag="ROH59_003861"
     CDS             320..1177
                     /gene="focA"
                     /locus_tag="ROH59_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HDX4806291.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLIGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
     gene            1232..3514
                     /gene="pflB"
                     /locus_tag="ROH59_003862"
     CDS             1232..3514
                     /gene="pflB"
                     /locus_tag="ROH59_003862"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDX4806292.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            3706..4446
                     /gene="pflA"
                     /locus_tag="ROH59_003863"
     CDS             3706..4446
                     /gene="pflA"
                     /locus_tag="ROH59_003863"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HDX4806293.1"
                     /translation="MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWD
                     THGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHT
                     CLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
                     NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYK
                     LDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(4543..5691)
                     /locus_tag="ROH59_003864"
     CDS             complement(4543..5691)
                     /locus_tag="ROH59_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806294.1"
                     /translation="MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGIGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQTENHDSTSITSMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            6005..6631
                     /locus_tag="ROH59_003865"
     CDS             6005..6631
                     /locus_tag="ROH59_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDX4806295.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDAPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRMSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            complement(6667..7530)
                     /gene="dmsC"
                     /locus_tag="ROH59_003866"
     CDS             complement(6667..7530)
                     /gene="dmsC"
                     /locus_tag="ROH59_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     DmsC"
                     /protein_id="HDX4806296.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMLGLWVLMGIGFISSMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLVVTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVMSVMQGAELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCVWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAN"
     gene            complement(7532..8149)
                     /gene="dmsB"
                     /locus_tag="ROH59_003867"
     CDS             complement(7532..8149)
                     /gene="dmsB"
                     /locus_tag="ROH59_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDX4806297.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            complement(8160..10604)
                     /gene="dmsA"
                     /locus_tag="ROH59_003868"
     CDS             complement(8160..10604)
                     /gene="dmsA"
                     /locus_tag="ROH59_003868"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HDX4806298.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGINNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDTKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            complement(10904..11896)
                     /locus_tag="ROH59_003869"
     CDS             complement(10904..11896)
                     /locus_tag="ROH59_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX4806299.1"
                     /translation="MSIKQLKDGRYQVDVRPQGAEGKRIRKIFALKSKAQEFEKYVLQ
                     NFHDKPWQAKPADQRRLSELLDAWWMLDGRNQAYGDSYRVRLGKVVREMGDPRASQMT
                     RKFMLEYRSEKLQAGLMPSSINRDLCVLSTMFTVLIEAEVFHNANPVRGIRKLKVQNT
                     EMAFLSDDEIERLLERLEGDVRRVAILCLSTGARWSEASELRGEHIVGNRVTFFNTKN
                     GKSRSVPVADSVVPLIKTRRTGLLYQVDYLKFREILQEVKPDLPKGQATHVMRHTFAT
                     HFMMNGGNIVTLQRILGHATIQQTMTYAHFSPDFLLDAINFNPLAESVHKLSID"
     gene            complement(11966..12307)
                     /locus_tag="ROH59_003870"
     CDS             complement(11966..12307)
                     /locus_tag="ROH59_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4806300.1"
                     /translation="MVILSIDYAKKLRQIRKAEGLTQKQFADITGLSLATIRNYESGQ
                     KNARAKIVEAVLQVDRFEKYMLWLIKDKTLPVAGQIAPALSLDGSIQSEGDQVSIGIT
                     QKSPRSGRNVG"
     gene            12412..12933
                     /locus_tag="ROH59_003871"
     CDS             12412..12933
                     /locus_tag="ROH59_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX4806301.1"
                     /translation="MRDFIADKELSDHQPLQESDALSGSIDAANDDEHEENKKKRSYK
                     KGATLRLDGPIAGLCSLEKGAAYIGLTKSALRVAIHRGQMPGHKTRTNPEDENSDGVW
                     WFNAKEWDKLADELPEHEPPEWHNWKSYWTYDRQKRKFSPANKEDCQTINGKRVYTGR
                     SSKLDQLRNNRGN"
     gene            12938..13360
                     /locus_tag="ROH59_003872"
     CDS             12938..13360
                     /locus_tag="ROH59_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806302.1"
                     /translation="MKTNTSDFTITISKNDQALIDNLKYLAEKHNNGRIAINLRHITG
                     VTIVTSYWHLYLIAKSVLENKDSVVNGRDIDTLPAQIKPIAYQLRNRFKNEGGIIFDF
                     PAAVAVSFSRGDILHSFRFALSGDETLWQLEDAGSSPA"
     gene            complement(13367..13558)
                     /locus_tag="ROH59_003873"
     CDS             complement(13367..13558)
                     /locus_tag="ROH59_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806303.1"
                     /translation="MSEDKKVVNLLSELSAALDNINPPRVKTTGDKDALNTEIHILLA
                     LVTDKIQRKYPPVTQLVDF"
     gene            13696..14046
                     /locus_tag="ROH59_003874"
     CDS             13696..14046
                     /locus_tag="ROH59_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4761 family protein"
                     /protein_id="HDX4806304.1"
                     /translation="MKLQRNSSQQRFRNGAERHANRFATSASRSNSRYSLSETHATPD
                     GYPVKQIGEHTWLIEKAGIVVHRCQRNPFTGNRIFALSNGDNQFGQDFTLYEALRTVD
                     RLLHGQSFIKQADL"
     gene            14057..14335
                     /locus_tag="ROH59_003875"
     CDS             14057..14335
                     /locus_tag="ROH59_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806305.1"
                     /translation="MTKEHAQGVFIRFIDFRGELLLRASAIDGVVPSEKNAATYVYLN
                     GTRLTVELPYQTVHEIISEAEKARKTNGDEPYIEIICMDSEAEIQKAD"
     gene            14347..14589
                     /locus_tag="ROH59_003876"
     CDS             14347..14589
                     /locus_tag="ROH59_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4754 family protein"
                     /protein_id="HDX4806306.1"
                     /translation="MGKEYKTLINKALERFYFRLSASGAHAERAARDSLTRAIRSLYD
                     VAFYADDLDALNELSELICAAECGEHIEPYKLGNIA"
     gene            14586..14699
                     /locus_tag="ROH59_003877"
     CDS             14586..14699
                     /locus_tag="ROH59_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806307.1"
                     /translation="MSIFMSWIVLIISVVCAIGIVRIIHSVKKIERFFTGE"
     gene            14793..15203
                     /locus_tag="ROH59_003878"
     CDS             14793..15203
                     /locus_tag="ROH59_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001376666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806308.1"
                     /translation="MHAKEEGIIRALKEISKTENEVAKKAIANNHMDVATHTLIVARV
                     TAEAAEIIAKQDAELAVLRTQPVTGLDLSNTGRLIYTIGSELQRYTIIAGLQDKYLIT
                     PHPIRESEILTNLRLIERSQVAFIDDAQCTVFNA"
     gene            15227..15430
                     /locus_tag="ROH59_003879"
     CDS             15227..15430
                     /locus_tag="ROH59_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806309.1"
                     /translation="MAIKHFPVVRFTSRGREYEVDERLITTIDKHRSEKDAHHIYLTD
                     GTYFCATNVARVNLIRQVQEPRR"
     gene            15427..15693
                     /locus_tag="ROH59_003880"
     CDS             15427..15693
                     /locus_tag="ROH59_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDX4806310.1"
                     /translation="MTILDYIATHPGCSGGEIAAALNTPTTAINAELRQLWRGGLVIR
                     TNRSTGGRARKTGGQASYHVNPMPFGCSNPLTHMFNQLLKEART"
     gene            15690..15989
                     /locus_tag="ROH59_003881"
     CDS             15690..15989
                     /locus_tag="ROH59_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806311.1"
                     /translation="MSTINHQKLRELAFALQRMATPQKLLAFRAMLSPSAALALLDEL
                     EHARTTAPAIRLTLHHEIADFCATLEVPGEPETPEAIQQELLQRIDKVFDFFLNQ"
     gene            16001..16618
                     /locus_tag="ROH59_003882"
     CDS             16001..16618
                     /locus_tag="ROH59_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HDX4806312.1"
                     /translation="MHTQKNRLPCRNQSGYISAAPHKTGAGFRSLLTTQAHNRASGFF
                     VRTVLPRFFRVRIMAGRTGPTSVGPGSCVAGTANLVRLATHSFAALDGEFSQLTTQGA
                     TPWQTANSTALSRSVVTSRLKSTADFPAHHASRKSCTSICCMSAATHYQTFIPPLFSA
                     IWRMICTSFNSSSSSKTNSINSCSGPFLHLAAGGLRTSVTRGLPQ"
     gene            16615..16980
                     /locus_tag="ROH59_003883"
     CDS             16615..16980
                     /locus_tag="ROH59_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806313.1"
                     /translation="MILANDFLEYLLNTERDLAARVRDRYDMYLKSLPVPQLADGKIV
                     IDGRYMIDSHEGNYRLYRIEGGTPSVIGIYQRPSSAIVDVIADSIRITHRHADTEDTV
                     LEIQRLATVCRDTLNGMTK"
     gene            16987..19809
                     /locus_tag="ROH59_003884"
     CDS             16987..19809
                     /locus_tag="ROH59_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HDX4806314.1"
                     /translation="MTAEYLRDWQQPRHAVGREGTGIPAPESALSSWLDAYRAENERR
                     QEMADAAFSATPLGNLINKSLDAQEKQDKTITLAGDARKQARGAVDEAMASLRLLPSY
                     LRDPLIRHLSFLRKKQEADRRKGKKSWQAERYARGTLRKIFERLDSTDGRWLTPGYRS
                     LAGRERLDDLLYLPQLNKHQIQTLATMTAAMFSSTFEKLCDGFGATDGELTMDVTLKA
                     YQMLARMALHLHAMPPHYDALTTDKDRRNEPDTELLPGAILRLTCAEWWKRKLWLLRC
                     EWREEQLRAACLVSRKTSPYLSQDALSEFRAQREKTRDFLKSFMLENEDGFTIDLETV
                     YYAGVSNPVHRKAEMMATMKGLELLAEARGDKAVFLTVTCPSKYHATTENGHPNPKWN
                     GATMRDSSDYLVNTFFAAVRKKLNRDGLRWYGIRTVEPHHDGTVHWHMMVFAHPEEID
                     TIVSHTRDIAIQEDRHELGNDITPRFKVEYVDGSKGTPTSYIATYIGKNLDSRAVDGI
                     DPKTGKPRVDHETGKSMAESVERAIGWARLHRVRQFQFFGIPSRQVWRELRRLASQMA
                     RNPEGPQRLKDDAMDAVLAAADAGCFATYIEKQGGVLVPRKDYLIRTAYDLADELNDY
                     GEQSVQIYGIWSPLIGESSRVCTHPDNWKLVRRKPEAEDSARENGFDLQGGPAAPWTR
                     GNNCPRVQETDNNGTEQPEERPAPWPQLPDGVEVNEWMRSLKRHERRALMRSLRDKQA
                     KNSSDEMQSWTQSRKQQRPLPDNHELLAKEWRESAESLGLHIGEQQMQHLLRGGSLYV
                     DGSIIAPQGFEIVRKPDTRPDSRITQLWQRLSRNHGVSSTEIRHNPVASYLAQLGASD
                     PEAAARLASTLQQGQNTMKTPVTVLSDMLRAIRDAEHAQRISETTERASRKADLLRGG
                     LTSGNKKQTETGLTNPVNEQKTRSDI"
     gene            19886..20845
                     /locus_tag="ROH59_003885"
     CDS             19886..20845
                     /locus_tag="ROH59_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HDX4806315.1"
                     /translation="MKICIDDGSTNIKLAWTENGERRNAISPNSFKSEWSAPFGGMQP
                     ANYMLDGVRYGFDPVSDRFVQTTDTQYQYSDVNVIAIHHALVKSGITPQEVDVVVTLP
                     LSEYFDTNAQPDMANINRKKANVMRPVEYQNGEAFTIRNVRVMPESIPAGFKALADMS
                     PFESLLIVDLGGTTLDVAKVQGQLAGISQVFCDPHVGVSLMADAVLSVMATNGMRTSH
                     HIANTIIEHRHDEAWLRQHIHNDAHYASLMAVIREKEETLKQRVIRALAVFSGYGRVM
                     VVGGGAEIVAPAIREVCGVNATFIADGVPQFALVNGLYAMDKE"
     gene            20850..21164
                     /locus_tag="ROH59_003886"
     CDS             20850..21164
                     /locus_tag="ROH59_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HDX4806316.1"
                     /translation="MTTPTRRISFYLKPAAVKSEQEACNYLDSLPASERSRAQRAAFL
                     AGLALIKRNPAFAYWMAEWPEDNLPFNTVSIKETYQDNQPSGVECNFYKIKKNIQTLF
                     PE"
BASE COUNT         5888 a         5648 c         5182 g         4992 t
ORIGIN      
        1 ttgcattaat aaaataattg taattataag gttaaatatc ggtaattcgt atttaataaa
       61 tacgatcgat attgttactt tattcgccag gtgctccctt ttaattaact gttttagcgg
      121 aggatgcgga aaaaattcaa ctcatttgtt aatttttaaa atttattttt atttggataa
      181 tcaaatattt actccgtatt tgcataaaaa ccatgcgagt tacgggccta taagccaggc
      241 gagatatgat ctatatcaat ttctcatcta taatgctttg ttagtatctc gtcgccgact
      301 taataaagag agagttagtg tgaaagctga caaccctttt gatcttttac ttcctgctgc
      361 aatggccaaa gtggccgaag aggcaggtgt ctataaagca acgaaacatc cgcttaagac
      421 tttctatctg gcgattaccg ccggtgtttt catctcaatc gcattcgtct tctatatcac
      481 agcaaccact ggcacaggta caatgccctt cggcatggca aaactgattg gcggcatttg
      541 cttctctctg gggttgattc tttgtgttgt ctgcggagcc gatctcttta cttccacagt
      601 gttgattgtt gttgccaagg cgagtgggcg catcacctgg ggtcagttgg cgaaaaactg
      661 gctaaatgtt tattttggca acctggtcgg cgcactgctg tttgtacttt taatgtggct
      721 ttccggcgag tatatgaccg caaatggtca atggggacta aacgtcctac aaaccgccga
      781 ccacaaagtg caccatactt ttattgaggc cgtctgtctt ggtatcctgg caaacctgat
      841 ggtatgtctg gcagtatgga tgagttattc tggccgcagc ctgatggaca aagcgttcat
      901 tatggtgctg ccggtcgcga tgtttgttgc cagcggtttt gagcacagta tcgcaaacat
      961 gtttatgatc ccgatgggta ttgtaatccg cgacttcgca tctccggaat tctggaccgc
     1021 tgtcggttct gcaccggaaa atttttctca cctgaccgtg atgaacttca tcactgataa
     1081 cctgattccg gttacgatcg gtaatattat cggcggtggt ttgttggttg ggttgacata
     1141 ctgggtcatt tacctgcgtg aaaacgatca ccattaatgg ttgtcgaagt acgcagtaaa
     1201 taaaaaatcc acttaagaag gtaggtgtta catgtccgag cttaatgaaa agttagccac
     1261 agcctgggaa ggttttacca aaggtgactg gcagaatgaa gtaaacgtcc gtgacttcat
     1321 tcagaaaaac tacactccgt acgagggtga cgagtccttc ctggctggcg ctactgaagc
     1381 gaccaccacc ctgtgggaca aagtaatgga aggcgttaaa ctggaaaacc gcactcacgc
     1441 gccagttgac tttgacaccg ctgttgcttc caccatcacc tctcacgacg ctggttacat
     1501 caacaagcag cttgagaaaa tcgttggtct gcagactgaa gctccgctga aacgtgctct
     1561 tatcccgttc ggtggtatca aaatgatcga aggttcctgc aaagcgtaca accgcgaact
     1621 ggacccgatg atcaaaaaaa tcttcactga ataccgtaaa actcacaacc agggcgtgtt
     1681 cgacgtttac actccggaca tcctgcgttg ccgtaaatcc ggtgttctga ccggtctgcc
     1741 agatgcttat ggccgtggtc gtatcatcgg tgactaccgt cgcgttgcac tgtacggtat
     1801 cgactacctg atgaaagaca aacttgcaca gttcacctct ctgcaggctg atctggaaaa
     1861 cggcgtaaac ctggaacaga ctatccgtct gcgcgaagaa atcgctgaac agcaccgcgc
     1921 tctgggtcag atgaaagaaa tggctgcgaa atacggctac gacatctctg gtccggctac
     1981 taacgctcag gaagctatcc agtggactta cttcggctac ctggctgctg ttaagtctca
     2041 gaacggtgct gcaatgtcct tcggtcgtac ctccaccttc ctggatgtgt acatcgaacg
     2101 tgacctgaaa gctggcaaga tcaccgaaca agaagcgcag gaaatggttg accacctggt
     2161 catgaaactg cgtatggttc gcttcctgcg tactccggaa tacgatgaac tgttctctgg
     2221 cgacccgatc tgggcaaccg aatctatcgg tggtatgggc ctcgacggtc gtaccctggt
     2281 taccaaaaac agcttccgtt tcctgaacac cctgtacacc atgggtccgt ctccggaacc
     2341 gaacatgacc attctgtggt ctgaaaaact gccgctgaac ttcaagaaat tcgccgctaa
     2401 agtgtccatc gacacctctt ctctgcagta tgagaacgat gacctgatgc gtccggactt
     2461 caacaacgat gactacgcta ttgcttgctg cgtaagcccg atgatcgttg gtaaacaaat
     2521 gcagttcttc ggtgcgcgtg caaacctggc gaaaaccatg ctgtacgcaa tcaacggtgg
     2581 cgttgacgaa aaactgaaaa tgcaggttgg tccgaaatct gagccgatca aaggcgatgt
     2641 cctgaactat gatgaagtga tggagcgcat ggatcacttc atggactggc tggctaaaca
     2701 gtacatcact gcactgaaca tcatccacta catgcacgac aagtacagct acgaagcctc
     2761 tctgatggcg ctgcacgacc gtgacgttat ccgcaccatg gcgtgtggta tcgctggtct
     2821 gtccgttgct gctgactccc tgtctgcaat caaatatgcg aaagttaaac cgattcgtga
     2881 tgaagacggt ctggctatcg acttcgaaat cgaaggcgaa tacccgcagt ttggtaacaa
     2941 cgatccgcgt gtagatgacc tggctgttga cctggtagaa cgtttcatga agaaaattca
     3001 gaaactgcac acctaccgtg acgctatccc gactcagtct gttctgacca tcacttctaa
     3061 cgttgtgtat ggtaagaaaa ctggtaacac cccagacggt cgtcgtgctg gcgcgccgtt
     3121 cggaccgggt gctaacccga tgcacggtcg tgaccagaaa ggtgctgtag cgtctctgac
     3181 ttccgttgct aaactgccgt ttgcttacgc taaagatggt atctcctaca ccttctctat
     3241 cgttccgaac gcactgggta aagacgacga agttcgtaag accaacctgg ctggtctgat
     3301 ggatggttac ttccaccacg aagcatccat cgaaggtggt cagcacctga acgttaacgt
     3361 gatgaaccgt gaaatgctgc tcgacgcgat ggaaaacccg gaaaaatatc cgcagctgac
     3421 catccgtgta tctggctacg cagtacgttt caactcgctg actaaagaac agcagcagga
     3481 cgttattact cgtaccttca ctcaatctat gtaattagat ttgactgaaa tcgtacagta
     3541 aaaagcgtac aataaaggct ccacgaaagt ggggcctttt ttagcacgag agcctttttt
     3601 gtcagctatc tatactttaa ggtgactgcc aaaacagact cgacgtagcc ttcgagctgc
     3661 gcaccaacac ggcctcagat gggccacatc tggagaaaca ccgcaatgtc agttattggt
     3721 cgcattcact cctttgaatc ctgtggaacc gtagacggcc cgggtattcg ctttatcacc
     3781 tttttccagg gctgcctgat gcgctgcctg tattgtcata accgcgacac ctgggatacg
     3841 catggcggta aagaagttac cgttgaagat ttgatgaagg aagtggtgac ctatcgccac
     3901 tttatgaacg cttccggcgg cggcgttacc gcatccggcg gtgaggcaat cctacaagct
     3961 gagtttgttc gtgactggtt ccgcgcctgc aaaaaagaag gcattcatac ctgtctggac
     4021 accaacggtt ttgttcgtcg ttacgatccg gtgattgatg aactgctgga ggtaaccgac
     4081 ctggtaatgc tcgatctcaa acagatgaac gacgagatcc accaaaatct ggttggagtt
     4141 tccaaccacc gcacgctgga gttcgctaaa tatctggcga acaaaaatgt gaaggtgtgg
     4201 atccgctatg ttgttgtccc aggctggtct gacgatgacg attcagcgca tcgccttggt
     4261 gaatttaccc gtgatatggg caacgttgag aaaatcgagc tcctccccta ccacgaactg
     4321 ggcaaacaca aatgggtggc aatgggtgaa gaatacaaac tcgatggtgt taaaccaccg
     4381 aagaaagaga ccatggaacg cgtgaaaggc attcttgagc agtacggtca taaggtcatg
     4441 ttctaatttc cccgtaaagc ggcaacttta ttgagttgcc gcttttttgt gcacagaaaa
     4501 gcagagtgtg aaacagtaag ttcacactct gcttgaattc atttacacgt gagccacggg
     4561 tttcggcgta tggccggcgt tgcgaagcag catcagcaaa tagataaacg atacgctggc
     4621 gatcatgata aacaataaat tatcggagaa attctgcatt agcatagcgg taaatgacgg
     4681 gccaagcagg cttcccacgg tatagctcaa cagtaaggcc tggttcatcg ccaccagttg
     4741 atgatgttca actttctcac aagcccaggc catcgccacc ggatatagcg taaagccagc
     4801 ggcaccgagg atgaataacg ctggggccat cgccgcctgg ctaagcatcg caatactgcc
     4861 gagaatgacg acaaagacct gaacacgcaa caccagcagt cgaccaaact tatccgccag
     4921 acgtccaatc ggccattgtc cgaggatacc cgcactgacc agtaccgcca tccagaaacc
     4981 aatgctggca ttgctcaccc ctttgtgatt gaggtacagc ggcatcaggc catatagaga
     5041 tcccagcacg attcctgaga taatgcagcc attcacgcca agccgcgcct gacggagttt
     5101 tagcattgac gtaattgacg tcgaatcatg gttttcagtc tgctgattca ggacacgcgt
     5161 aaacaacagc ggtaagattc ctgccaacgt caaacctgta acccacggca atacactcat
     5221 caactcggtt gagactttgc tgaccagtaa ctggcctaaa aacgttccga cgtaataaac
     5281 catcatatac gcagcaagca accgcccgcg gttacgcgac gtcccactgc acatcagcgc
     5341 actctcaaca accacccaaa tcatggcaca gccgatgcca gcgacaaaac gccacgccaa
     5401 ccaactccag aatccaatca tcaggccaag gccggcacag ccagcggcaa aaatgaagga
     5461 ggccagataa tagctgcggt taaagccaat gcgtttaatg acataccctg tcagcaatgt
     5521 accgacaagg ttgccggtaa aataggatga gctgacaacg cctacctgcc atgtagacat
     5581 gtgttcctgg gcgagccaaa gcggcacgag tgtatttaac accgcgatcg ccagagtcaa
     5641 caaaagcagg ccagacagca aaagcatgac aggccgggta tacgtggaca tgaattaaaa
     5701 ccgtgaggaa gttcaaattt catgcgcatc atgccaccgc caaaaacatt gtcaatgggt
     5761 gaaaatacgc gcatatcgca gcggcggtat tatcgattta tattactcat tcataacgct
     5821 aatgctgaag agacgattaa tctcatctga ttgtttttat tgatctaaca caaatttcat
     5881 acgcttcgtt cagtcgaaaa atttcatggt cacagcaaac tcatatttcc cgtctatgct
     5941 ttcagagcaa tgcatcgcgt ctgaccgatt tagacgtacc actgactctc gaaaggagaa
     6001 gaggatgacc aaaccgtatg ttcgtcttga taaaaatgat gctgccgttt tgcttgttga
     6061 tcaccaggct ggtttacttt cccttgtacg ggatatcgaa cccgataagt ttaaaaataa
     6121 cgtgctggcg ctgggtgacc tggctaagta tttcaactta ccaactattc ttaccaccag
     6181 ttttgaaacc ggtcctaacg gcccattagt tccagaactg aaagcacaat tccccgatgc
     6241 accttacatt gctcgcccgg gaaatattaa cgcctgggat aacgaagatt ttgtaaaagc
     6301 tgtcaaagcg acaggtaaaa aacagttaat tattgccggt gtggtaaccg aagtttgcgt
     6361 ggcattcccg gcgctttcag ccattgaaga agggtttgac gtctttgtcg tgactgacgc
     6421 gtcagggacc tttaatgaaa ttacccggca ttcggcatgg gatcgcatgt cgcaagctgg
     6481 tgcgcaattg atgacatggt tcggcgtggc gtgcgagctg catcgcgact ggcgtaatga
     6541 tattgaagga ctggcgacgt tgttctctaa ccacattcct gattatcgta acttgatgac
     6601 cagttatgac acgttaacga agcagaaata aaagcgaacc ggggccgaaa ccccggttgt
     6661 tactgattaa tttgcgacag ccatccccac ggtcatatgc aaaccataga atacgccacg
     6721 accgattaat tcccctgcca gaagcagaat gaatgataca gaaagtagcg gaaccgcagg
     6781 ctgataacct tttagctgtg gtgcaatcca cacgcacagg gcaacggcca aaagcacgat
     6841 ccgccaggac atcagcgcac catagtccgg caccagcgct gcggcctgct gcacagagct
     6901 atgaatagtc gccagctctg cgccctgcat cactgacatc acgccactca ctaccagtgc
     6961 cagaacagaa atggctggca gcagacgcat cgcccagcca tcgacgccag ccagactcag
     7021 caacaggtaa cccagtaacg ggccgcccat aaacatcgtc aggaagaagc ccatcggtgt
     7081 ccagatgctg taccaggtgg gtactgtatc gatgctgtta tacacacgca ccatcatcca
     7141 gacaaagact acgccaagaa ccatcgtcac caccagccaa agcgtacgca atgccggtga
     7201 aagctttttc agcattgcca gcaaccagcc gatgccgcct acagcaaaaa agatcgaacc
     7261 gctggcgatt tcgttactga gtgctgaagc ccctacccga ttgagcgagt taaaagcgcg
     7321 catcggtgaa ccaagatgaa gcatagagga gataaagcca atgcccatca gcacccataa
     7381 acccaacatg caggcgataa cacgctgctg ggcttctgct cgcaggtcgc ctttgagcag
     7441 cgccaaagcc agaacgataa aaccacccgc gacacattgc ccgaagaccg tgaagatcat
     7501 cagcggccat tcatgccatc cacttcccat ctcacacctc cttcgggttt gccagatagc
     7561 cagtggtatc cccggttggg cggctgttgg cattgggttt gatcacaata ttcggtttgg
     7621 taaagtgagc tcgcggcaac ggcgcaacgg ccgccagatc gccatgtttt ttacgcagct
     7681 cgtcgatagg gccgaaatcc agcgcccgta gcgggcagga ctctacgcag atcggttttt
     7741 ttccctccgc aacacggtca taacaaccat cgcatttggt catatggcct ttcgtttcgt
     7801 tatattgcgg tgcgccatac gggcaagcca tatgacagta acggcagcca atgcatacat
     7861 cttcatcgac cacaacaaaa ccatcttcac gtttatgcat cgcaccgctc gggcagactt
     7921 tagtacaagc cggatcttcg cagtggttac atgaaatcga cagatagtag gcaaacacgt
     7981 tctggtgcca gacaccgtta tcttcctgcc agtcgccacc agcatattca taaatgcggc
     8041 ggaagctgac ttctggcgtc aaatctttgt agtctttaca agccagctcg caggttttgc
     8101 aaccggtgca acggctggaa tcaataaaaa atccatactg ggttgtcatc ggttactcct
     8161 tacacctttt caacctgaac aaggtttgta tgtgacggat tccccttagc gagaggagac
     8221 ggacgttgag tggtcagtac gttaatacaa ccgcccttat cgacacgttt tgtatccggg
     8281 tcataccagg caccttcacc cagtgcgacc acacccggca tcattcgtgg cgtcactttc
     8341 gcctcaatat gaacctcacc acgatcgtta aagatcctga ctttatcgcc gttgttgata
     8401 ccgcgttttt gcgcatcaag cgggttgatc cacatttcct gacggcaagc tgctttcagc
     8461 acatcaacgt tgccgtaagt tgagtgaacg cgagatttat agtggaaacc cgtaagctgc
     8521 agcggatact gtttgttcag cggatcctga taactttcaa aacccggcgt atagatcggc
     8581 agtggatcga tcacatcacc ttctggcaat tcccaggtag cggcaatgtc agccagcgcc
     8641 tgcgaataaa tctcaatttt ccccgatggc gtggtcagtg gatttgcctg cggatcttca
     8701 cggaaagctt tataagcaac gtgatgccct tgtgggtcgc gctttttaaa aatcccctgc
     8761 ttacggaact cttcaaacgt tggcagttca ggaatcgctt cccgcgactg ggcatacaga
     8821 tgccgcatcc actcttcctg ggtacggccc tcagtaaact gttgctcaac gccaagacgt
     8881 tttgccagtt cgctggtcat ttcatagatg gtcttacatt caaagcgcgg tttaatcacc
     8941 tgatcgttga aaatcacgta agacatattc ccgcaggatg catccagtgc aaagtccatc
     9001 tgttctgaag cggtgcagtc aggcagcagg atgtcagcat atttcgccga tgaggtcatg
     9061 tggcagtcga taaccacaat cagctcgcac ttcttatcat cctgaaggat ttcatgggta
     9121 cggttgattt cagaatgctg gttaatcagg cagttaccgg catagttcca gatcattttg
     9181 atcggcacat ccagcttatc tttcccgcgc acaccatcac gcagcgctgt catttccggg
     9241 ccacgttcaa tggcatcggt ccacataaac atcgaaatgc tggtctggat cgggttttcg
     9301 agggtcggca tacggacaaa cggtaagctg tatgaacctt cacgcgcgcc gctgttgcct
     9361 ccgttaatac caacgttacc ggtcagaatc gccagcatcg agatagcacg ggttgcgatt
     9421 tcaccgttag cgtgacgctg cgggccccat ccctggctga taaacgccgg tttggtacta
     9481 ccgatttcac gagccaattt gatgattttg tctgccggaa caccagtgat ttgcgaggcc
     9541 cattccggcg ttttagccac gccatctggc ccttcaccca gaatataagc tttatagtga
     9601 ccatttttcg gcgcactggc tggcagtgtt ttctcgtcgt agccaacgca atatttatcg
     9661 aggaatgcct gatccaccag gttttcggtg atcatgacat acgccagacc gttaaccagt
     9721 gcggcatctg ttcccggacg aatagggatc cactcatctt cgcgcccggc accggtgtcg
     9781 gtatagcgcg gatcgatgat gatcatgcga gcattagatt tctggcgcgc ctgttcaaga
     9841 tagtaagtca ccccaccgcc actcattcgc gtttcgccag ggttattacc aaacagcact
     9901 accagtttac tgttttcgat atccgacggg ctgttaccat ctgcccagcc gccgtaggta
     9961 tagttcaaac cttccgcaat ttgcgcggaa gagtagtcac cgtaatggtt cagataaccg
    10021 ccgcagcagt tcatcaggcg cgcgaccagg gtatttcccg gcggccagga gcgggtcatg
    10081 gtgccaccca gcgtaccggt gccatagttc agatagatgg attcgttgcc gtactctttg
    10141 atcaggcgct gcatattggt cgcgatgatg tcgtaggctt cttcccagct aatgcgctcg
    10201 aatttgcctt caccgcgcgc cccgactcgt ttcatcggat atttcaggcg gtcgggattg
    10261 taaacgcggc gacgcatgga acgaccacgc agacaggcgc gcacctggtg caggccgtca
    10321 tagttgtcat cgccagtatt atccgtttca acatatttga tttcaccgtc cacgacgtgc
    10381 atacgtagcg ggcagcgact accacagtta actgtacagg cgctccagat aaccttttcg
    10441 tctgattttg ttggaatggc gctatcgaca gcgtgcgcaa tccgactaaa aggtaatgtt
    10501 aatgcgctgc tggccattgc caggccgccg atcgctgtcg tttttaccaa accacggcga
    10561 ctcacctcag cagccaatac cgcatcaggg attttcgttt tcataatggc tcactcaagc
    10621 ttgctcacga ttgattccag taacaaaccg tattgtgtaa ttatttctat agcagatcgc
    10681 tatataggct tgtatacatc gaataatttg aaaatcaaag agataggtgg attttcactc
    10741 gaaagtagta ttacttgtaa gtgaggagta attattgttc ggtatcaaag ggagacaaaa
    10801 aaagcgcccg caggcgcttt aacgtttctt gcccctcctg atgatttact tatttttcaa
    10861 cgaataagcc aaaacagggg gaacaaatta acacaaatta taactaatcg atggacagtt
    10921 tatggacact ttcagccagc ggattaaagt tgatcgcgtc cagtaaaaag tccggcgaaa
    10981 aatgagcgta cgtcattgtt tgctgaatcg ttgcgtgccc caggattcgt tgcaacgtaa
    11041 caatatttcc gccattcatc ataaagtgtg tggcaaatgt atgacgcatg acatgcgtag
    11101 cctgcccctt cggcaaatcc ggtttcacct cctgaagaat ctcccggaac ttcagataat
    11161 caacctgata caataacccc gttcgacggg ttttaatcag aggcacgacc gaatccgcca
    11221 caggaaccga acgggatttt ccgtttttgg tgttaaagaa cgtcacccgg ttgccaacga
    11281 tatgctctcc acgtagttcc gatgcttcac tccatcgggc accagtagaa agacacagaa
    11341 tggcaacacg acgcacatca ccctccagtc gctcaagaag ccgttcaatc tcatcatcag
    11401 aaagaaaggc catctctgtg ttctgaactt tcagttttcg tataccgcgt acagggttcg
    11461 cgttgtgaaa gacctcagct tcaatcagca ccgtgaacat ggtagacagt acgcataagt
    11521 cacgattaat actggacggc attaatccgg cctgtaattt ctctgaccga tattcaagca
    11581 taaattttcg cgtcatctga ctggcgcgag gatctcccat ttcacgaaca accttcccta
    11641 gcctaaccct gtagctatcc ccgtaagcct gattacgccc atcaagcatc caccacgcat
    11701 caagcagctc tgataatcgc cgctgatcag ctggcttagc ctgccatggc ttgtcatgaa
    11761 agttctgtaa cacatacttc tcaaactcct gagcctttga tttcagggca aagatttttc
    11821 gaatccgctt tccttccgcc ccctgcggtc tgacatcgac ctgataacgt ccgtctttga
    11881 gttgcttaat cgacatgatt agcccctcca acggataaat taactaaaca ctccttgcga
    11941 tatgtaattc gctcaatgtg tagagtcagc caacattgcg gcctgatcgg ggtgattttt
    12001 gggtaatacc gattgaaacc tgatcgccct ccgactgaat agatccatca agagagagag
    12061 ccggagcaat ctgcccggcg acaggtagcg tcttatcttt tattagccac agcatgtatt
    12121 tttcaaagcg atcgacttgc agaaccgcct caacgatttt tgctctagcg ttcttttgcc
    12181 ccgattcgta attccttatg gttgccaaag acaacccagt aatatccgca aactgctttt
    12241 gtgttaaccc ttccgcctta cgtatctgac gtaacttttt tgcgtagtct attgacaaga
    12301 taaccatttg agtattaacc tctcgcacaa agataacctt ttggttatct ttacaagcca
    12361 aaacaaacca tcacaaggcg cgacaagcgc accaacgcaa gaggataaca aatgcgggac
    12421 ttcattgccg ataaagagtt atctgaccac caaccacttc aggaaagtga cgcactcagc
    12481 ggatccattg atgccgccaa cgacgacgag cacgaagaaa acaagaaaaa gcgttcctac
    12541 aaaaaaggag cgactttgcg gctggatggt ccgatcgccg ggctttgctc tctggaaaaa
    12601 ggcgcggcat atattgggct aacaaaatct gcactgcgcg tagccattca tcgcggtcaa
    12661 atgccgggac acaagacgcg cacaaacccg gaagatgaaa actcagacgg agtatggtgg
    12721 tttaacgcca aagagtggga caagttggct gatgagctac cagagcacga gcccccagaa
    12781 tggcacaact ggaaaagtta ctggacgtat gaccgccaga aaaggaagtt ctctccagct
    12841 aataaagaag actgccagac cattaacggt aagcgagttt atacaggcag aagctcaaaa
    12901 ctggaccaac tcagaaacaa cagaggcaac taatcgtatg aaaacaaaca cgtcagattt
    12961 cacaataact atttcaaaaa atgaccaagc attaattgat aacctgaaat accttgcgga
    13021 aaaacataat aacggacgaa ttgcaattaa tttacgacac atcacaggag taacaattgt
    13081 aaccagttac tggcatctat atctaatcgc taaatcagta cttgaaaaca aagattctgt
    13141 tgtcaatgga agagatatag atactcttcc tgcacaaatc aaaccgatag cctatcaatt
    13201 gcgtaatcgt tttaaaaatg aaggtgggat tatatttgac tttcccgcag ctgtagccgt
    13261 gagcttctct cggggggata tacttcactc atttcgtttt gctctatcag gtgacgagac
    13321 attatggcag ctagaagatg ccgggagcag cccggcataa atcaaattaa aaatcaacca
    13381 gttgtgtgac aggtgggtat ttacgctgaa ttttgtcagt tactaacgcc agtaatatat
    13441 gaatctctgt gtttaatgcg tctttatcac ccgtcgtttt taccctggga gggttaatgt
    13501 tatccagagc agcactaagt tcactcaaca aattaacaac ttttttatct tctgacatga
    13561 aaacctctta acaatttaat taaacataag ccaggacctg aaccggccag tccaagtcct
    13621 agacacacaa aaaaaatacc acaaatcaat acaaggtgac acgagtacac cttaccgaag
    13681 gtacagagtt ttaatatgaa actacagcgc aattcttcac agcagcgctt ccgcaacggt
    13741 gcggaacgcc atgctaaccg tttcgctacc agtgcatcac gtagcaactc tcgctacagc
    13801 ctgagcgaaa cacacgcaac gccggatggc tacccagtaa aacaaattgg tgaacacact
    13861 tggctgattg aaaaagcagg aatcgtggtt cacagatgcc agcgcaaccc atttaccgga
    13921 aaccgcattt ttgcactgag caacggcgac aatcagttcg ggcaggattt cacattatac
    13981 gaagcacttc gcacggttga tcgtctgctt cacgggcaaa gttttattaa acaggctgat
    14041 ttataacagg tgctttatga ccaaagagca tgcacaaggt gtatttatcc gttttattga
    14101 ttttcgcggt gaactgttat tacgcgcatc agccattgac ggagttgttc catccgaaaa
    14161 aaatgcagct acttacgttt atctgaacgg cacgcgcctg accgtagaac ttccgtacca
    14221 gactgtacac gaaatcatta gcgaagcgga aaaagcacgt aagactaatg gcgatgaacc
    14281 ctatatcgaa attatttgta tggattcaga agcagaaatt cagaaagcag attaaagggc
    14341 gttgcgatgg gcaaagaata taaaactctc attaacaaag cacttgagcg tttttatttt
    14401 cgcttaagtg catcaggcgc tcatgctgaa cgtgcagccc gtgactcatt gaccagggca
    14461 atccggagtc tgtatgacgt ggctttttac gctgatgatc tggatgcact taacgaactt
    14521 tccgagctga tctgtgccgc agaatgcggg gaacatattg aaccgtataa gctggggaat
    14581 atcgcatgag tatatttatg tcatggattg ttctgattat ttcagtggtc tgcgcaattg
    14641 gcattgtgcg aattattcat tcagtaaaaa agattgaacg ttttttcact ggtgaataac
    14701 gatacaaata aaacatcaaa ttaaataaga aaacgtgaaa accatccgta ttaacggagg
    14761 tattcgcaca cgcaaataac ggagatacaa aaatgcacgc aaaagaagaa ggtatcatca
    14821 gagcactgaa agaaatttca aagacagaaa acgaagtagc gaaaaaagcc atagcaaata
    14881 atcatatgga cgtcgcaacc cacacactga tagtcgcaag agtcacggca gaagcagccg
    14941 aaattatcgc aaaacaggat gctgaactgg cggttctcag aacacaacca gtcaccggac
    15001 tggatttgtc taacaccgga cgccttattt acacaattgg ctcggagcta cagcgataca
    15061 ccattatcgc cgggttacag gataaatacc tgatcactcc tcaccccata agggaatcag
    15121 aaattctgac aaatctccgc ctgatagagc gctctcaagt cgcattcatt gatgacgcac
    15181 agtgcaccgt atttaacgca tagagttact ggacaaaggg ggcgcaatgg caattaagca
    15241 ttttcccgtc gttcgcttta cctccagagg gcgcgaatac gaggtcgacg aacgcctgat
    15301 taccactatc gacaaacatc gttcggaaaa ggatgcacac cacatctacc tcactgacgg
    15361 cacttacttc tgcgccacta atgtggcgcg ggtaaacctt atccgacagg tacaggagcc
    15421 acgcagatga ccattctgga ctacatcgct actcatccgg ggtgtagcgg cggagagatc
    15481 gccgcagcac tgaatactcc aaccacagcc attaatgctg agttacgcca actttggcgc
    15541 ggcggcttag tcatcagaac aaaccgcagc acaggtggtc gcgctcgcaa aactggaggc
    15601 caggcttctt accacgtaaa cccgatgccg ttcgggtgta gcaatccact tactcacatg
    15661 tttaaccagc tactgaagga agccagaaca tgagcaccat caaccaccag aagctacgcg
    15721 aactggcatt tgccctgcaa cgaatggcaa cacctcaaaa attactggca tttcgcgcaa
    15781 tgctctcgcc gtctgctgcg ctggcattgc tggatgagct ggagcacgcc agaaccacgg
    15841 ctcctgccat tcgcctgacg ctccatcatg aaatcgctga tttctgcgcg acattggagg
    15901 tgccaggcga accggaaacg ccggaagcaa tacagcaaga gctgctgcaa cgtattgaca
    15961 aggtttttga tttttttctg aaccagtaag aaaccagagc atgcacacac aaaaaaaccg
    16021 cttgccatgc cgcaatcagt caggttacat ttccgctgca cctcataaaa cgggtgccgg
    16081 gtttcgcagc ctgctgacta cacaagcgca caaccgcgcc agcggttttt ttgtgcgtac
    16141 tgtattgcca cgtttttttc gcgtcagaat tatggcgggg cgtacggggc cgacttcggt
    16201 cgggccgggt tcttgtgtag ccggtactgc gaacctcgta cgtctcgcca cccacagttt
    16261 cgcagctctg gatggtgagt tttcacaact tactacacaa ggggccacac catggcaaac
    16321 cgcaaacagc accgcgctat cgcggagcgt cgtcacatcc agactgaaat caaccgcaga
    16381 ctttcccgcg catcacgcgt cgcgcaaatc atgcacatca atatgctgca tgagcgcagc
    16441 cacgcactat caaacattta ttccgcctct gttttcagct atctggcgga tgatctgcac
    16501 gagcttcaac agctcatcca gcagcaaaac aaactccatt aattcctgtt ccgggccttt
    16561 cctgcacctt gcggcgggag gccttcgcac atctgtaaca agaggattgc cgcaatgatt
    16621 ctcgccaacg actttcttga atacctgctc aatacagaac gtgatcttgc cgctcgcgtg
    16681 cgtgatcgtt atgacatgta cctgaaatcc ctgcctgtac cgcagctcgc tgacggaaag
    16741 attgttattg atggtcgcta catgattgac agccacgagg gaaattacag gctttaccgc
    16801 attgaaggtg gcaccccgtc cgttattggc atttaccagc gcccatcctc tgcaatcgtc
    16861 gatgtgattg ccgacagcat ccgcatcaca catcgccatg ccgacacaga agacaccgtg
    16921 ctggaaattc agcggctggc tacagtctgc cgcgacaccc tgaatggcat gacgaagtaa
    16981 atcactatga cggcagagta cctcagggac tggcaacaac cgcgccacgc agtggggcgt
    17041 gaaggaacgg ggatccccgc tcctgaatcc gcgctttcct cctggctgga tgcctaccgg
    17101 gcagagaacg agcgccgcca ggaaatggct gatgcggcgt tctcagccac gccgctgggc
    17161 aacctgatta ataaaagcct ggacgcacag gaaaaacagg acaaaaccat cacactggca
    17221 ggagacgcca gaaaacaggc acgtggcgcg gtggatgaag ccatggcctc gctgcgcctg
    17281 ctgccgtcct atctgcgcga tccgcttatt cgccacctct ccttcctgcg caaaaaacag
    17341 gaagccgatc gccggaaagg caaaaagagc tggcaggcgg aacgctatgc acgcggaacc
    17401 ctgcgcaaaa tattcgaacg tctggatagc actgacggac gctggctgac accgggttat
    17461 cgctcccttg ccggacgcga acgcctggac gatttgcttt acctgccgca gctcaacaaa
    17521 caccagatac agacgctggc caccatgacg gcggcgatgt tcagcagcac cttcgaaaaa
    17581 ctctgcgatg gctttggcgc gaccgatggc gagctgacca tggatgtaac cctgaaggcg
    17641 tatcagatgc tggcccgcat ggcgttacac ctgcacgcca tgcctccaca ttatgacgca
    17701 ctgacaacag acaaagaccg gaggaacgaa ccggacacgg agctgctgcc gggcgcaatc
    17761 cttcgcctga cctgtgcgga atggtggaaa cgcaaactgt ggctgttacg ttgcgagtgg
    17821 agagaagaac aactccgcgc cgcctgtctg gtttccagaa aaacatcacc ctatctgagc
    17881 caggacgcgt taagcgagtt tcgcgcacag cgcgagaaaa cacgcgattt cctgaaaagt
    17941 ttcatgctgg aaaatgaaga cgggttcacg attgatctcg agacagtgta ttacgcggga
    18001 gtaagtaacc cggttcaccg taaggcagaa atgatggcca ccatgaaggg actggaactt
    18061 ctggccgaag cccgtggcga caaagcggtg tttctgactg tcacctgccc gtcaaaatac
    18121 cacgccacaa cggagaacgg tcatccgaat cccaaatgga acggggccac aatgcgcgac
    18181 tccagcgatt acctggttaa cacgtttttt gcggcggtcc gcaaaaaact gaaccgcgac
    18241 ggcctgcgct ggtatggcat ccgcacggtg gagcctcatc atgacggcac cgtgcactgg
    18301 catatgatgg tctttgcaca tccggaagaa atcgacacca ttgtgtccca tacccgcgat
    18361 attgccattc aggaagaccg ccacgagctg ggcaatgata ttactccgcg ctttaaggtg
    18421 gagtatgtcg acggctcaaa aggcacgcca accagctaca tcgccaccta catcggaaag
    18481 aacctggaca gccgcgccgt ggatggcatc gacccgaaaa cgggcaagcc acgcgtggac
    18541 cacgaaaccg gaaaatcaat ggccgagagc gtggagcgcg ccatcggctg ggcgcgcctt
    18601 caccgggtcc gtcagttcca gttctttggc atcccctccc gtcaggtgtg gcgtgaactg
    18661 cgccgccttg ccagccagat ggcacgcaat ccggaaggcc cgcaacggct gaaagatgat
    18721 gcaatggatg cggtactcgc tgccgccgat gccgggtgtt ttgccaccta cattgaaaaa
    18781 cagggtggcg tgcttgttcc acgcaaggac tacctgattc gcaccgccta cgacctcgca
    18841 gatgagctga acgattacgg cgaacagagc gtacagattt acgggatctg gtcaccactc
    18901 atcggggaat cctcccgtgt gtgcacgcat ccggataact ggaagctggt aagacgtaaa
    18961 ccggaagcgg aagacagcgc ccgcgaaaat ggttttgacc ttcagggcgg ccctgccgcc
    19021 ccttggactc gtggcaataa ctgtccccgt gtacaggaaa cggacaacaa cgggacagaa
    19081 cagccggaag aacggccagc accgtggccg cagctccctg acggcgttga agtgaacgaa
    19141 tggatgcgct cactgaaacg acacgaacgc cgggcgctga tgcgttcgct tcgtgacaaa
    19201 caggcaaaaa acagcagcga tgaaatgcag agctggacac agagccgcaa acagcagcgg
    19261 cctttgcctg ataaccacga attactcgct aaagaatggc gggagtctgc tgaatctctc
    19321 ggcctgcata tcggtgaaca acagatgcag cacctgttac ggggcggcag tctgtacgtt
    19381 gacggcagca tcattgcacc gcagggattt gaaattgtac gcaaaccgga tacccgcccg
    19441 gacagccgaa tcacgcagct ctggcagcgc ctgagccgta atcatggcgt aagcagcacg
    19501 gagatccgcc ataacccggt cgccagctat ctggcacagc tgggggcatc agaccctgaa
    19561 gccgccgcac gcctggcatc cacacttcag cagggccaga acaccatgaa aacacccgtt
    19621 accgtgcttt ctgacatgct gcgcgccatc cgcgacgcag agcacgcaca gagaatcagt
    19681 gaaaccactg aacgcgccag ccgcaaagca gacctgctgc ggggtggcct gaccagtgga
    19741 aacaaaaaac agacagaaac gggacttacg aatcccgtaa atgagcaaaa aacgcgcagc
    19801 gatatatgaa gcgcgcacaa aacaggcaaa aacgggattt cagaatcccg taaacgatta
    19861 attaatcaac ataaggaaaa gcgacatgaa aatttgtatc gacgacggct ccaccaacat
    19921 caagctggca tggactgaga atggcgaacg ccgcaacgcc atcagcccga acagcttcaa
    19981 gtcggaatgg tctgcgccgt tcggtggcat gcagcccgcg aactacatgc ttgatggcgt
    20041 gcgctatggt tttgatccgg ttagcgatcg ctttgtccag acgaccgaca cgcaatacca
    20101 gtacagcgat gtgaatgtaa tcgccattca tcacgcgctg gtcaaatcag gcatcacgcc
    20161 acaggaggtg gatgtggttg tcaccctgcc actgagcgag tatttcgaca caaacgcaca
    20221 gccggacatg gccaacatca accgcaaaaa agcgaacgtt atgcgcccgg tggaatacca
    20281 gaacggcgaa gcattcacta tccgtaacgt gcgggttatg cctgaatcca ttccggctgg
    20341 ctttaaagca ctggctgaca tgagtccgtt tgaatccctg ctgattgtgg atttaggcgg
    20401 aaccacgctg gatgtggcaa aggttcaagg gcaactggca ggtatcagcc aggtgttttg
    20461 cgatccacac gtaggcgttt ccctgatggc cgatgccgta ctgtcggtga tggccactaa
    20521 cggtatgcgc accagtcacc acatcgccaa taccattatc gaacatcgcc atgatgaagc
    20581 ctggctgcgc cagcacatcc acaatgacgc gcattacgcc agcctgatgg cggttattcg
    20641 tgaaaaggaa gaaacactga aacaacgcgt gatccgcgcg ctggcggttt tttcgggtta
    20701 cgggcgggtg atggttgtcg gtggaggggc ggagattgtg gcacccgcta tccgcgaagt
    20761 ctgcggagtt aatgcgactt tcatcgcgga cggggtgcca cagtttgctc tggttaatgg
    20821 gctgtacgca atggacaagg agtaaaccaa tgacgacacc aaccagacgg ataagtttct
    20881 atctgaagcc cgccgccgtc aagagtgaac aggaggcgtg caattacctc gatagcctgc
    20941 cagcctccga acgcagccgc gcgcaacgcg cggcctttct ggctgggcta gcgctcataa
    21001 agcgcaaccc agcatttgcc tactggatgg ccgaatggcc agaggacaac ctccccttca
    21061 ataccgttag catcaaggaa acataccagg ataatcagcc tagcggagtt gaatgcaatt
    21121 tttataaaat aaaaaagaat attcagacct tattcccaga ataatctgat aattgtatgt
    21181 gaactaataa aatacagacc aacacatcat tctggcaccc ttgctaacag ggtgccaatg
    21241 tttcaaatca tgatgaaatt gccgaagttt ttttatcgtg ctgaagtacc gcaaatgcca
    21301 ttaaaacctc aagagaatag cggcgataat acttaacaaa accataataa aatactcggg
    21361 atgcagcaat acaaaacaag agaagaaaac aaaaaggtaa cagtctgata tttatatcta
    21421 ttaaaaagga tagaaggagc aggaacataa gcaaccagac tgaagcgaga aaaacaaatg
    21481 taatgtttct acaaaaacca tacaaagcaa catagttttg cattttcacc tgatgatttt
    21541 tagaatgttc atacacataa tgataagcaa ggcgaaaaag atcgcccctc aagcccttac
    21601 gtcgatatag cgtagataca gaaaaaacat ttatataacc atctcgtatt tgcggccaaa
    21661 agactttaat aagtatagaa tgcagtgtgg ttttatgatg ttctgcttta
//
LOCUS       DAPOXO010000085        21443 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPOXO010000085 DAPOXO010000000
VERSION     DAPOXO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21443
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.085"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..412
                     /locus_tag="ROH59_003887"
     CDS             <1..412
                     /locus_tag="ROH59_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDX4806317.1"
                     /translation="NGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIPFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG"
     gene            472..1833
                     /gene="allB"
                     /locus_tag="ROH59_003888"
     CDS             472..1833
                     /gene="allB"
                     /locus_tag="ROH59_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HDX4806318.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGG
                     IAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQ
                     PNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILK
                     HQQ"
     gene            1889..3190
                     /locus_tag="ROH59_003889"
     CDS             1889..3190
                     /locus_tag="ROH59_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HDX4806319.1"
                     /translation="MFNFAVGRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IAAPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYSRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            3212..4357
                     /gene="glxK"
                     /locus_tag="ROH59_003890"
     CDS             3212..4357
                     /gene="glxK"
                     /locus_tag="ROH59_003890"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HDX4806320.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTIFPDAHYICLPIADG
                     GEGTVEAMVAATDGNIVKLEVCGPMGEKVNAFYGITGDGKTAVIEMAAASGLMLVVPE
                     KRNPLLASSFGTGELILHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQP
                     LAANGGNLARVASIEMNECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQLTEINVCQMAGGGAAGGMGIAAAVFLNEDIKPGIEIVLNAV
                     NLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(4486..5271)
                     /gene="allE"
                     /locus_tag="ROH59_003891"
     CDS             complement(4486..5271)
                     /gene="allE"
                     /locus_tag="ROH59_003891"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HDX4806321.1"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFVN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFA
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYIPVEGHAPWLVYGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(5282..6517)
                     /gene="allC"
                     /locus_tag="ROH59_003892"
     CDS             complement(5282..6517)
                     /gene="allC"
                     /locus_tag="ROH59_003892"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HDX4806322.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKKMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDATVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL
                     VATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            complement(6539..7588)
                     /gene="allD"
                     /locus_tag="ROH59_003893"
     CDS             complement(6539..7588)
                     /gene="allD"
                     /locus_tag="ROH59_003893"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HDX4806323.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QKGVAVVGISRMGHSGAISYFVQQAARAGLIGISLCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSS
                     ELFRQHLSQTMRELNTITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     gene            7905..9572
                     /locus_tag="ROH59_003894"
     CDS             7905..9572
                     /locus_tag="ROH59_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDX4806324.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAVMQQLEKALKQLAQGSGSSQAL
                     TQVRRWDSASQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLK
                     TRAREKGLLVMGPDCGTSMIAATPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAETVRLKIVNAMK
                     ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADGHQILDLGDDFYTVGRPHPMI
                     DPTLRNLLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPATQQHTPSLL
                     ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     gene            9582..10841
                     /locus_tag="ROH59_003895"
     CDS             9582..10841
                     /locus_tag="ROH59_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDX4806325.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNKGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRTLAPQIACLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            10852..11667
                     /locus_tag="ROH59_003896"
     CDS             10852..11667
                     /locus_tag="ROH59_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDX4806326.1"
                     /translation="MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPP
                     AHPQPLAVAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAAAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     gene            11664..12557
                     /locus_tag="ROH59_003897"
     CDS             11664..12557
                     /locus_tag="ROH59_003897"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDX4806327.1"
                     /translation="MKTLVVALGGNALLQRGEALTAKNQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     gene            complement(13091..14158)
                     /gene="purK"
                     /locus_tag="ROH59_003898"
     CDS             complement(13091..14158)
                     /gene="purK"
                     /locus_tag="ROH59_003898"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDX4806328.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARQPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAE
                     RSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRAAETEQLPAECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQLQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NNPSVMINLIGSDLNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSHLTATLEA
                     LIPLLPPEYASGVMWAQSKFS"
     gene            complement(14155..14664)
                     /gene="purE"
                     /locus_tag="ROH59_003899"
     CDS             complement(14155..14664)
                     /gene="purE"
                     /locus_tag="ROH59_003899"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDX4806329.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     gene            complement(14760..15089)
                     /locus_tag="ROH59_003900"
     CDS             complement(14760..15089)
                     /locus_tag="ROH59_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806330.1"
                     /translation="MQRCNGFLISGIALTAGAPLCISWFGLVGFYFGALSLVAAAVIS
                     WIVYFWLIYLVLTRPHNQRFVERYILIVGICFLPWSIVLIWAFFASSARAHNQHAEQI
                     KNSTTDG"
     gene            complement(15200..15922)
                     /gene="lpxH"
                     /locus_tag="ROH59_003901"
     CDS             complement(15200..15922)
                     /gene="lpxH"
                     /locus_tag="ROH59_003901"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HDX4806331.1"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            complement(15925..16419)
                     /gene="ppiB"
                     /locus_tag="ROH59_003902"
     CDS             complement(15925..16419)
                     /gene="ppiB"
                     /locus_tag="ROH59_003902"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HDX4806332.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKDPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            16593..17978
                     /gene="cysS"
                     /locus_tag="ROH59_003903"
     CDS             16593..17978
                     /gene="cysS"
                     /locus_tag="ROH59_003903"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDX4806333.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMNDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            complement(18014..18535)
                     /locus_tag="ROH59_003904"
     CDS             complement(18014..18535)
                     /locus_tag="ROH59_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX4806334.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKAIPPRLLFAGIILAMLPDADVLS
                     FKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKWVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLP
                     GMLLMGMLWWRRR"
     gene            complement(18643..18855)
                     /gene="ybcJ"
                     /locus_tag="ROH59_003905"
     CDS             complement(18643..18855)
                     /gene="ybcJ"
                     /locus_tag="ROH59_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HDX4806335.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGLVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            complement(18857..19723)
                     /gene="folD"
                     /locus_tag="ROH59_003906"
     CDS             complement(18857..19723)
                     /gene="folD"
                     /locus_tag="ROH59_003906"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HDX4806336.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQGE"
     gene            19994..20070
                     /locus_tag="ROH59_003907"
     tRNA            19994..20070
                     /locus_tag="ROH59_003907"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20028..20030,aa:Arg,seq:tct)
     gene            complement(20086..20687)
                     /locus_tag="ROH59_003908"
                     /pseudo
     CDS             complement(20086..20687)
                     /locus_tag="ROH59_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415069.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            20694..21068
                     /locus_tag="ROH59_003909"
                     /pseudo
     CDS             20694..21068
                     /locus_tag="ROH59_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885581.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(21123..>21443)
                     /locus_tag="ROH59_003910"
     CDS             complement(21123..>21443)
                     /locus_tag="ROH59_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDX4806337.1"
                     /translation="GQFDSISMFYLLHCLPGNISTKSCVIRNAAQALTDDGTLYGATI
                     LGDGVVHNSFGQKLMRIYNQKGIFSNTKDSEEGLTHILSEHFENVKTKVKGTVVMFSA
                     SGKK"
BASE COUNT         4960 a         5434 c         5839 g         5210 t
ORIGIN      
        1 aaacggcgta ctgattgcca gtattatcag cctgctgatc tgtccgtgga aattaatgga
       61 aaatcaggac agtatttatc tgttcctcga tattatcggc ggaatgcttg gtccggtaat
      121 tggtgtgatg atggcgcatt attttgtggt gatgcgtggg caaattaatc ttgatgaact
      181 gtacaccgca cctggcgatt ataaatatta cgataacggt tttaacctca ccgcgttttc
      241 agtaactctg gtggccgtta ttttatctct tggcggtaag tttattccct ttatggaacc
      301 gttatcacgt gtttcatggt ttgtcggcgt catcgtcgcc tttgcggcct acgccttatt
      361 aaagaaacgt acaacagcag aaaaaacagg agaacaaaaa accataggtt aattaatcac
      421 gatattgaac attgagttaa aaaccaatct gtattttaca aggagtttgt tatgtctttt
      481 gatttaatca ttaaaaacgg caccgttatt ttagaaaacg aagctcgcgt tgtagatatc
      541 gccgttaaag acggaaaaat tgctgctatc ggccaggatc tgggcgatgc aaaagacgtt
      601 atggatgcgt ctggtctggt ggtttcgccg ggcatggttg atgcgcacac ccatatttct
      661 gaaccgggtc gcagccactg ggaaggttat gaaaccggta ctcgcgcagc agcaaaaggt
      721 ggtatcacca ccatgatcga aatgccgctc aaccagctgc ctgcaacggt tgaccgcgcc
      781 tcaattgaac tgaagttcga tgccgctaaa ggaaagctga ctatcgatgc ggcacaactc
      841 ggtggcctgg tgtcttacaa cattgaccgt ctgcatgagt tggatgaagt gggtgttgtc
      901 ggtttcaaat gcttcgttgc gacctgtggc gatcgcggta tcgacaacga cttccgtgac
      961 gtcaatgact ggcaattctt caaaggcgcg cagaagctgg gcgaactggg ccagccagtg
     1021 ctggtgcact gcgaaaacgc gctgatctgt gacgcactgg gcgaagaagc gaagcgtgaa
     1081 ggtcgcgtaa ctgcccatga ctatgtggct tcgcgtccgg tatttaccga agtggaagcg
     1141 attcgccgcg tactgtacct ggcgaaagtc gctggttgcc gtctgcacgt ttgccacgtc
     1201 agcagcccgg aaggtgttga ggaagtgact cgtgcacgtc aggaaggtca ggatgttact
     1261 tgtgaatcct gcccgcatta ctttgtgctg gataccgatc agttcgaaga aatcggtact
     1321 ctggcgaagt gttcaccgcc gatccgcgat ctggaaaacc agaaaggcat gtgggaaaaa
     1381 ctgtttaacg gtgaaataga ctgcctggtt tccgaccact ctccatgccc gccggaaatg
     1441 aaagccggta acatcatgaa agcgtggggc ggtatcgctg gtctgcaaag ctgcatggac
     1501 gtgatgttcg atgaagcggt acagaaacgc ggaatgtctc tgccaatgtt cggcaaatta
     1561 atggcgacta acgcagcaga tattttcggt ctgcagcaaa aaggccgtat cgccccagga
     1621 aaagatgccg acttcgtctt cattcagccg aatagcagct atgttcttac caatgacgat
     1681 ctggaatatc gccacaaagt cagcccgtat gttggccgta ctattggcgc gcgtatcacg
     1741 aaaaccatct tacgtggtga tgtgatttac gacatcgaac agggcttccc tgttgcgccg
     1801 aaaggtcaat ttatccttaa acatcagcag taatctggcc ctgcaatgcc cgtccttgtg
     1861 gcgggcattc tccggttaag gtgtgtttat gttcaatttt gcagtgggcc gcgaaagcct
     1921 gttatcagga ttccagtggt ttttctttat tttttgcaac acggttgtgg ttcctcctac
     1981 gctactttct gcttttcagt tgccgcaaag tagcctgctt acgctcacgc aatatgcttt
     2041 tcttgctacc gcactggcct gcttcgctca ggcgttctgc ggtcatcgtc gcgctattat
     2101 ggaagggccg ggcggcctgt ggtggggaac catcctgact atcacccttg gcgaagcatc
     2161 gcgcgggaca ccgatcaacg atatcgctac cagtctggcg gtggggattg cgctctccgg
     2221 cgtgctgacg atgttgattg gttttagcgg attaggccat cgcctggcac ggttatttac
     2281 gccgtcggtg atggtcttgt ttatgttgat gctgggtgcg caactgacca ctatcttttt
     2341 caaaggtatg ctcgggctgc cgtttggcat agccgccccg aattttaaaa ttcaattacc
     2401 gccgttcgcg ctctcggtgg cggtgatgtg cctggtactg gcgatgatta ttttcctgcc
     2461 acaacgtttt gcccgttacg gcctgctggt cggcacgata actggctggt tgttgtggta
     2521 cttttgcttt ccttcttcgc attcgctctc cggtgagttg cactggcagt ggttcccgct
     2581 cggcagtggc ggtgctttgt cgccggggat tattctgacg gcggtgatta caggtctggt
     2641 aaatatcagc aatacctacg gtgcgattcg gggcacggat gttttttatc cgcagcaggg
     2701 cgcggggaat acgcgttatc gtcgcagctt tgtggcgacc ggatttatga cactgataac
     2761 cgtgccgctg gcagtaattc cattttcacc gtttgtttca tccattggtt tattaaccca
     2821 gacaggcgat tactcgcggc gttcgtttat ttatggcagc gttatttgcc tgctggtggc
     2881 actggttccg gcactcacgc gactgttttg cagtatccct ttaccagtga gtagtgcggt
     2941 catgctggtt tcttatctgc ctttactctt ttccgcgctg gtgtttagcc agcaaataac
     3001 gtttaccgct cgcaatattt atcgactcgc attgccgtta tttgtcggca tatttttaat
     3061 ggcattaccg cctgtgtatc tgcaagacct tccattaacg cttcgtcctc tgctcagtaa
     3121 cggcttactg gtcggaattt tactggctgt tcttatggat aatcttattc cgtgggaacg
     3181 catcgaataa tttgttgaaa aaggattgat aatgaagatt gtcattgcgc cagactcttt
     3241 taaagagagc ttaagtgcag aaaaatgttg tcaggcaatt aaagccgggt tttcgaccat
     3301 atttcccgat gcgcactata tctgtttgcc gatagcggat ggcggcgaag ggacggtgga
     3361 ggcgatggtc gccgcgacgg acggtaacat cgtgaagctt gaagtctgcg ggccgatggg
     3421 cgaaaaagtg aatgcttttt atggcattac cggcgacggg aaaacggcgg tgattgagat
     3481 ggcagcagca agtggcctga tgctggtcgt gcctgaaaag cgtaatccgt tgctggcctc
     3541 cagttttggt acgggggagt taattctcca tgcgctggat aatggcattc gccatattat
     3601 tctcggcatt ggcggcagtg cgacggtcga cggcggtatg ggcatggcgc aggcgctcgg
     3661 tgtgcgtttc cttgatgccg acggtcagcc gctggcggct aacggcggca atttagcgcg
     3721 cgtggcaagt attgagatga atgaatgcga tccgcgtctg gcgaactgtc atattgaagt
     3781 agcatgtgac gttgataacc cgctggtagg ggcacgcggc gcggcggcgg tgtttggccc
     3841 gcaaaaaggg gcaacgccgg agatggtcga agagctggaa caggggctgc aaaattacgc
     3901 ccgtgtttta caacagctaa ctgaaatcaa cgtctgccag atggcgggtg gtggcgcggc
     3961 gggcggtatg ggcattgcgg cggcggtatt cctcaatgag gatattaaac cgggtattga
     4021 gattgtgttg aatgcggtca atcttgcgca ggcagtgcag ggtgcagcac tggtgatcac
     4081 cggggaaggg cgcatcgact cgcaaacggc aggcggtaaa gcgccgctgg gtgtggcatc
     4141 ggtggcgaag cagtttaatg tcccggtgat tgggattgct ggcgtattgg gtgatggcgt
     4201 ggaagtggtg caccagtacg gcattgatgc ggtattcagc attttgccac gtctggctcc
     4261 tttagccgaa gtgctcgcca gcggtgaaac caatctcttc aacagtgcgc gaaatattgc
     4321 ctgcgccatt aaaataggtc agggaattaa aaactgacta ttacctttaa agcggatgcg
     4381 atttatatcg catctttttt tacctgaatt gactacaaaa aaagccacgg aataaaccgt
     4441 ggcaaaatcc aacatagcta aaaataatca ggcgagtggt atgacttaaa tctctacgtc
     4501 gcggttgcaa tctttcgagt aaatatagct gaacgcttca ccacgcccta cgccataacc
     4561 agcctgtaaa gaataagcgc ccataaagat gtaatcgcct tttttcaccg ggatccagtt
     4621 attgtcgagg ttataaaccc cctgaccgga aagaatatag gcaccgtgtt cctgaacgtg
     4681 ggtttcgata taaccgtggc tggcacctgg tgcaaaagag aggatatgca tgttcatatc
     4741 aaaacctaac tctttgggca gaaaatccag cagaataaca tcgtccatgc cttcataatg
     4801 aatgcgttcc agttcgctgg cattgccata aaccagccac ggcgcatgac cttctaccgg
     4861 aatatagcga cgcttatata aaaagatttg gctgtcttcg gcctgggcgt taacaaacgt
     4921 cattaaggag cctggcgggc aataaagata gccaccttcg cttaaggcaa atgttttccc
     4981 ttcggctttg gcagtgatat ttccagagat cacatacagg aacgtttcaa tgccttcgcc
     5041 accgaagccc tgttggttgc cgccgttttg atgcagtgtg accagataat caacaaaaga
     5101 ggcacccagc tttggcgtgg agaggattgt cgcgtcacaa tttacaaagc ccggaataat
     5161 attttttacc agaccgtctg gtgttaacag tgcgaaatta ccgtgtttaa caatcgcacg
     5221 gttagccagt aaatcatcgc ggtaaccggt gacgttattt aaatatccca tttataactc
     5281 cttatttctg ccaggcaagt tgataaagca tgagtgccaa cgttttgacc ccttcggcaa
     5341 ggtcggtaat attggtgcgt tccgccgggt tatggctgat cccgttgatg ctgggaatga
     5401 aaatcatgca ggtcggcacg cgaggcgcga aaatttgcgc gtcgtgcccg gcaccactgt
     5461 gcatcacccg gtaattcagt ttttcgcttt cacacaattc tgtcagggtg gcgaccagct
     5521 ccttattcat cggcacgggt tcttcgtcca tccataaatc gatatcaata ccaatatcca
     5581 tttcatcgca aatcgcccgc atgtcgtttt ctaactgttg ggtgaaatcg cgcagcacgg
     5641 tagcatcggt atgacgacaa tcaatggtga acgtggtttt acccggcact acattcaccg
     5701 tattcgggcg cggctctact ttgccaaaag tcagaaccag cgggtcgccc atctttttcg
     5761 ctttttcgac agactgatgg caaatgcgac tgaaagcgta aaccgtatca cgacgataac
     5821 ccatcggcgt ggtgcctgca tggtttgatt caccgttcag cgtcaccgta tagcgacgtt
     5881 gcccgacaat tgcattcacc acgccaattg actgcccatt actttccagc acacagccct
     5941 gttcgatatg cagttcgaca aaggctttaa tatcctgacg cggagttagt ggggcgttcg
     6001 gcagagtaaa tccgcaagcc ttcatcgcat cgacaaaact atttcctttg gcatcacaga
     6061 tattccgcac gtcgtcagga ttcgccagcc caaaaatatt tttactgccc cagaaaacat
     6121 acgggaagcg gctgccttct tcttctgcca tcgccaccac ttcgaccgta cgtaacggcg
     6181 cgccgtattg cgttttcagc cagtcaattg ccagccacgc cgccagcgca ccgaattgcc
     6241 cgtcgaggtt accgccgtta accacggtat cgatatgcga accgctcaga accacttcct
     6301 gtggatattc ggtgccattc aggcgaccgt ataaattccc cacttcatcg aaacgtgttt
     6361 ccagcccgct tgctgccatt ctttttttaa actgctgctg ggtttccagc cattccggcg
     6421 aataaagtaa acgggtcatc ccacccgctg ggtcagcgcc aaaagaggaa agccagggca
     6481 gcgtttcttc tatagcttga cggaaatgtg taatcataag aaagtcctgt ctcaataatt
     6541 attgcgcaaa gggatttttc gtttcgtatg acgtgttata aagcgcgtcg gaaattaaat
     6601 actggtaaat atcatcaaca atttcgatgc cttcgacggc ggctttgcgt tgtttaatat
     6661 cctgatcctg tccgggataa taaacctgat taaaaccggg cgcgggggta atggtattta
     6721 attcgcgcat ggtctggcta agatgttgac ggaataattc gctggaggag aaaaagttcg
     6781 ggttaataac tatatgtaat tgccccaaat tacgcccggc gtgtaaatcg tcatacatcg
     6841 aactaacctg tcgcccgaac ggtaagccga gtaagacgcc tgagaggacg tcaatcatca
     6901 tcatcaggcc ataccctttt ggcccagcgg cggggagcag agcatgtacc gcgaacggat
     6961 cggttgttgg tgcaccgttt ttatcgactg cccaggtatc cgggatagac atattgcgcg
     7021 agcgggcgtc gagtactttt ccccatgcct gtacggtagt cgccatatca aaggtaagga
     7081 tctcgtcgcc ttctcccggc gcggcaaagg ccagtgggtt agtgccgtag taaatttccg
     7141 cgccgccaaa cggcaccacc attggatcgg actggcacag cgaaatgcca atcaatccgg
     7201 cgcgggcagc ctgctgcaca aaataagaga ttgcgccgct gtgacccatc cggctgatac
     7261 cgaccaccgc aacgcctttt tgctgggcgg ttttgatggc atgttccata cccattttcg
     7321 ccgcgacctg tccggcggca ttgtcggcat gtaaaattgc cgagcacggt ccggtttcct
     7381 caagacgaaa ctccggttcg cggttggtgc cgccttttga aatgcgttcg gcgtagtatt
     7441 caacgcgcac cgcgccatga gagtggatcc ctctggcatc ggcgtaaacc aatacttcag
     7501 ccacggttgc agcgtgctca cgttttaacc cagcctggca gagtttattc tcgattagct
     7561 ggtggagtgt ttcccgactg attttcatct gtcttccttt ttaacgacgg tgtgaagcat
     7621 gactgcaatt aacatacagg gaaaatatct ggattatgtg atccagacag gcaaaaaaat
     7681 atagttagaa tttatttgat aatcttcgtg cttttaacct ggtttttaaa acaaccatgc
     7741 ttattaaaaa ataacgcgta atagtctggc ggttatttga attcttttgt taataatccc
     7801 cgtgtgatat tcatcacctt atttactcgt tgtcatcgat accgtaatcg ccacattaac
     7861 actgctcgtg caattgccat gggtgcaatt tttaaggagt tgttatgatc cacgccttta
     7921 ttaaaaaagg gtgttttcag gattcggtca gtttaatgat tatttcacga aaactcagcg
     7981 aatcagaaaa tgttgatgat gtttccgtaa tgatgggtac gcccgccaat aaagcgttat
     8041 tagatactac aggtttctgg catgacgatt ttaataacgc cacgccgaac gatatttgcg
     8101 tggcaattcg tagcgaagcg gcggatgcgg ggatcgcgca ggcggttatg cagcagcttg
     8161 aaaaggcgct aaaacaactg gcgcagggtt caggcagcag ccaggcgttg acgcaggtgc
     8221 gtcgctggga cagtgccagt cagaaattac ccgatgccaa tctggcgctg atttcagtgg
     8281 ctggtgagta tgcggcggag ttggcgaacc aggcgctgga tcgcaacctc aacgtgatga
     8341 tgttctccga taacgtcacg ctggaagatg aaatccaact taaaacccgc gcgcgggaaa
     8401 aaggcttgct ggtgatgggg ccagactgcg gtacgtcgat gattgctgcc acgccgctgg
     8461 cttttgctaa tgtgatgccg gaaggcaaca ttggcgtcat aggcgcttcc ggtaccggga
     8521 ttcaggagct gtgctcacag attgcgctgg caggggaggg aattactcac gcgattggtc
     8581 ttggcgggcg cgatctcagc cgtgaagtgg gcggcatcag tgcgctaacg gcgctggaaa
     8641 tgctcagtgc agacgagaaa agcgaagtgc tggcatttgt ttcaaaacca cctgccgaaa
     8701 ctgtgcgtct gaaaattgtt aatgccatga aagcaactgg caaaccgacg gtggcgctgt
     8761 ttttaggtta taccccggcg gtggcccgcg acgagaatgt ctggtttgcc tcctcgctgg
     8821 atgaggccgc tcgtctggct tgtctgcttt cacgcgtcac tgcgcgacgt aacgcgatag
     8881 cgcctgtcag cagcggattt atttgcggtt tgtataccgg cggtacgctg gctgctgaag
     8941 cggcgggatt acttgccgga caccttggcg tggaagccga cgatacccat caacatggca
     9001 tgatgctgga cgccgacgga catcagatcc tcgacctggg cgatgatttt tacaccgtcg
     9061 ggcgtcccca tccgatgatc gacccgacct tacgcaacct gttaattgcc gatctcggcg
     9121 ctaaaccgca agtgcgagtg ttgctgcttg atgtcgtgat tggcttcggc gcgaccgccg
     9181 atcctgccgc ctcgctggtg agcgcctggc aaaaagcctg tgccgcgcgt tcagacaatc
     9241 aaccactgta tgccattgcc acggtgacag gcactgaacg tgacccgcaa tgccgctcgc
     9301 agcaaatcgc cacgctggaa gatgcgggga tcgcggtagt gagttcgcta ccggaagcca
     9361 ccttgctggc tgcggcgtta attcatccgc tctcgcctgc cacacagcaa cacacaccgt
     9421 cattactgga aaacgtcgcc gtgattaaca tcggattacg cagctttgcg ctggagctac
     9481 aaagcgccag caaaccggtt gtgcattacc aatggtcgcc agtcgccggc ggcaataaaa
     9541 aactggctcg tttattagaa cgtttgcaat aaggggttcc catgtttaca tcagtggcgc
     9601 aagccaatgc tgcggttatc gaacaaattc gtcgtgctcg tccacactgg ctggatgtgc
     9661 aaccggcttc ttcacttatc agcgaactaa acaagggcaa aacactgctt cacgccgggc
     9721 cgccaatgcg ctggcaggag atgaccggac ccatgaaagg ggcgtgcgtg ggcgcatgtc
     9781 tgttcgaagg ctgggcgaaa gatgaagcgc aggcgctggc aatactggag cagggggaag
     9841 tgaacttcat tccttgtcac catgtgaatg ccgtcgggcc aatgggcggc attacttctg
     9901 ccagtatgcc gatgctggtg gtcgagaacg tgaccgacgg caaccgggcg tactgcaacc
     9961 tcaacgaagg tatcggcaaa gtgatgcgtt ttggcgctta cggcgaagat gtcctgactc
    10021 gccatcgctg gatgcgcgat gtgttaatgc cagtattaag cgcggcgctg gggcgcatgg
    10081 agcgcggtat cgatctcacg gcaatgatgg cgcagggcat taccatgggc gatgagttcc
    10141 atcaacgcaa tattgcttcc tcagcactgt taatgcgtac gctggcccca caaattgctt
    10201 gcctcgatca tgataaacag cacattgcgg aagtgatgga ttttctcagc gtgaccgatc
    10261 agttcttcct caacctcgcg atggcctact gcaaggcggc gatggatgca ggcgcgatga
    10321 tccgcgcagg cagcatcgtt acggctatga cccgcaacgg caatatgttc gggattcggg
    10381 taagcgggct gggtgaacgc tggtttactg cgcctgtaaa cactccgcaa ggtctgtttt
    10441 tcaccggctt ctcgcaggag caggcgaacc cggatatggg cgatagcgcg attaccgaaa
    10501 cctttggtat cggaggtgcg gcaatgatcg cagcgcctgg cgtaacgcgc tttgtcggtg
    10561 cgggtggcat ggaagcggcc agagcggtat ctgaagagat ggcggaaatt taccttgaac
    10621 gcaatatgca gttgcagatc cccggctggg atttccaggg ggcgtgcctg gggctggaca
    10681 ttcgtcgcgt ggtagaaacc ggcattacgc cactcatcaa taccggtatc gcccataaag
    10741 aggcggggat cgggcagatt ggcgcaggca ccgtgcgggc accgctggcg tgctttgaac
    10801 aggcgctgga agcactggct gaaagcatgg ggattggttg aggaacgcac aatgacgatc
    10861 atccatcctc tgcttgccag ccgtagcgca ccgaattatc gccagtcctg gcggttagcg
    10921 ggagtgtggc ggcgggcgat taacctgatg acggaaagcg gcgaactgtt aacgctgcat
    10981 cgtcagggga gtggtttcgg ccccggcgga tgggtgcttc gccgcgcgca attcgatgcg
    11041 ttatgcggtg gattatgcgg caatgaacga ccacaggttg tggcacaagg tattcgtctc
    11101 gggcgtttca cggttaaaca gccacagcgt tattgtttgc tacgtattac gccgcctgcg
    11161 catcctcaac cgcttgccgt tgcatggatg caacgcgcgg aggaaaccgg gcttttcggg
    11221 ccactggcat tggcggcaag cgatccgctg cctgctgaat tacgccagtt tcgtcactgt
    11281 tttcaggccg cgctcaatgg cgttaagacc gactggcggc actggctggg taaaggcccc
    11341 ggattaacgc caagtcatga tgacacgctg agcggaatgc tgctggcggc ctggtattat
    11401 ggcgctttag atgcgcgctc cggtcgcccg ttttttgcct gttccgacaa tcttcaactc
    11461 gttaccactg cggtgagcgt cagttattta cgttatgccg cgcaaggata tttcgcctcg
    11521 ccactcctgc actttgttca tgcgctgagt tgcccgaaac gtaccgcagc ggcgatcgat
    11581 tcgctgctgg cgctggggca tacgtcaggg gcagatacgc tgctggggtt ctggcttggc
    11641 caacaattat tacaagggaa accatgaaaa cactggttgt ggctcttggg ggcaacgcct
    11701 tactccagcg cggtgaggcg ctgacggcaa aaaatcaata tcgcaatatt gccagtgctg
    11761 tacccgcgct ggcgcgcctg gcccgttctt atcggctggc aattgttcac ggcaacggac
    11821 cgcaggtggg gctgctggcg ttacagaatc tggcgtggaa agaggtagaa ccgtatccgc
    11881 tggatgtact ggtggcggaa agccagggga tgattggcta tatgctggcg cagagcttga
    11941 gcgcacagcc gcagatgccg cctgtcacga cggtgctgac gcgcattgag gtttcgcctg
    12001 atgatccggc gtttttacag ccagagaagt ttatcggtcc ggtttatcag ccagaagaac
    12061 aagaggcact ggaagcggct tacggctggc agatgaaacg tgatggtaaa tatttacgtc
    12121 gggtggtggc gtctccgcaa ccgcgtaaaa ttctcgacag cgaagccatc gagttgttgc
    12181 tcaaagaggg gcatgtggtg atttgcagtg gcggcggtgg tgtgcctgtg acggaagacg
    12241 gggcagggag tgaagcggtg attgataaag atctcgccgc tgcgttgctc gccgagcaga
    12301 ttaatgccga tggactggtg atcctcaccg atgctgatgc ggtatatgaa aactggggaa
    12361 cgccgcagca acgtgccatt cgccatgcca caccggatga gttagcgcca tttgccaaag
    12421 ccgatggttc gatggggccg aaggtaacgg cggtgagtgg ctatgtcaga agccgtggta
    12481 aacccgcgtg gattggggcg ttatcgcgga ttgaagagac gctggcgggc gaagcgggga
    12541 cttgtatttc gctgtagtga tgggcaccag gcaattggca catctagcct gatgcgatgc
    12601 tggcgcgtct tatcaggtct acaggcggtg tcggaacggt aggccggata aggcgttcac
    12661 gccgcatccg gcaatcggca caccatgcct gatgcgatgc tggcgcgtct tatcaggcct
    12721 acagtcggtg tcggaacggt aggccggata aggcgttcac gccgcatccg gcaatcggca
    12781 caccatgcct gatgcgatgc tggcgcatct tatcaggtct acaggcggtg ttggaacggt
    12841 aggccggata aggcgttcac gccgcatccg gcaatcggca caccatgcct gatgcgatgc
    12901 tggtgcgtct tatcaggtct acaggcggtg tcggaacggt aggccggata aggcgttcac
    12961 gccgcatccg gcaatcggca caccatgcct gatgcgatgc tggtgcgtct tatcaggtct
    13021 acaggcggtg ttggaacggt aggccggata aggcgttcac gccgcatccg gcaatcaaat
    13081 gagcaccagg ttaactgaac ttactctgcg cccacatcac gccgctggca tactccggtg
    13141 gcagcagcgg gattaaggct tccagcgtcg cggtcagatg cgatgtgtcg ctgtcggtca
    13201 aatttaaatg ccccacttta cggcccggac ggacttcttt gtcgtaccag tgcagatgca
    13261 caagcggcag tttcagccag tcataattca gatcgctacc aatcagattg atcatcaccg
    13321 acggattatt cactactggt tgcggtaacg gcagatcggt aattgcccgc agatgtagct
    13381 caaactggct gatgctggca ccgttttgcg tccagtgccc actgttatgc acacgcggag
    13441 ccagttcgtt gatcagcaga ccttgcggcg tgacaaaaca ctccatcgcc atcacgccca
    13501 catagcccag ctcctgcata atcgccgaca acatctcttc agcttgcgcc tgcagctgtg
    13561 cgttggcctg cgggaaagcg acgctggtgc gcaaaatgcc gtcctgatgc aggttatgcg
    13621 tcagcggata aaacacggtg ctgccatcaa aaccgcgcgc gccaaccagc gacacttcac
    13681 ctgagaagtt tatgccctgc tcgacaatac attcgccgta gcattcagcc ggtaactgtt
    13741 cggtttcagc ggcgcgtaaa cgccattgac cgcgtccgtc atagccacca gtgcggcgct
    13801 taacaatcgc cagctcacct aaacgatcaa acaccgcagg ccactcgctg cgttcggcaa
    13861 gtaactgcca cggtgcggtc ggcaggtgga gcttatcgaa aagctgcttc tgagtcagac
    13921 ggtcggcaat aatcgggaac acatcgcggt tcacaaaggc cggctggcgc gccagctcgc
    13981 gggttaatgc agtttccggc cagcgttcga tctcagcggt aatcacgctt tgttgaaaag
    14041 gcaccgccgc cggttcagcg tccagcccga ccggccagac agcaatgcct aacggttcgc
    14101 ctgcctgacg cagcatacgg cctaactgcc cgttaccgag gacgcaaacc tgtttcatgc
    14161 cgcacctcgc gggtccgggt tttccagcac ttcatcagtt tgtgctttgc gccagtcatt
    14221 cagacgctgg tgcagttctt tatcatgagt cgcaagaatt tgtgctgcca gtaacgccgc
    14281 gtttgccgcg ccagctttac caatcgccag cgtacccacc ggaatgccgc gcggcatttg
    14341 tacgatggag tagaggctat cgacaccgct cagtgcggcg ctctgtactg gcacgcccag
    14401 caccggcacc agcgttttgg cggcaatcat gccaggcagg tgcgctgcgc cgcctgcgcc
    14461 cgcaataatc acctgataac cgttctcttc ggcgctttcg gcgaagctga acagtttatc
    14521 gggggtgcgg tgagcagaaa ccacttcaac gtggtgcggg acattcagga tttcgaagat
    14581 ttcggcggcg aactgcatgg tagcccagtc gcttttggac cccatcacga tggcgacacg
    14641 cgccggatta ttgcgggaag acatgcgtct taaaactcct gtggtgcaca actctcggct
    14701 ttagagggca cagagaatag cacggaaaga gtgctaggaa aacggttgcg taggcggaat
    14761 taaccgtcag ttgttgagtt tttaatttgt tctgcgtgtt gattatgcgc tctggctgaa
    14821 ctggcaaaga atgcccatat cagcacaatg ctccacggta aaaagcatat accgacaatc
    14881 aatatatatc tttctacaaa gcgttggtta tgggggcggg tgagtactaa ataaatgagc
    14941 cagaaataga ctatccagga aatgaccgcc gcagctacca gtgacaatgc gccaaaatag
    15001 aagccgacaa gaccgaacca gctaatacac agtggcgctc ctgccgtaag ggcgatgcca
    15061 gaaatcaaaa atccgttgca gcgttgcata ataatattcc ctgttgttat ttcactcaga
    15121 gattattacc ttgctgattt taaaaaagat atacaggttg cgttagttcg gtgctttttc
    15181 agaatctgtc cattcgtggt cagaaaggaa aatggattag ctcaacgtca tccgccgtga
    15241 ctttcaccat cgaaccttct gtatgccagg cacccagtac cacgcgaaaa gcaggttgct
    15301 gattggcgat aagttcatgc accgccgggc gatgggtatg cccgtggatc agccattgca
    15361 cttgatgttt ttccatcgca ctgaccaccg cgttttggtt aacgtccatg atcgccagcg
    15421 atttactgct gttggcttct ttactgttcg cgcgcattcg cgcggcaatg cgtttgcgca
    15481 caaacaacgg cagggcgagg aatagcgttt gcagccaggg tttgtggact ttggcgcgaa
    15541 aagcctgata acccgcgtca tcggtgcaca gcgtgtcgcc atgcataatc aacacccgac
    15601 gaccataaag ttcgagcacc ttttcttccg gcaataacgt catgccgctt tcacgggcaa
    15661 agcgtttgcc gagcagaaaa tcacggttgc catgaatgaa ataacaggga acgccggaat
    15721 cggataccgc tttgatcgct gcggccatct ggtgatgaag tgggttggga tcgtcgtcgc
    15781 cgatccaggc ttcaaacaga tcgccaagaa tatacagcgc atcggccttg cgggcctccc
    15841 ctgctaaaaa acgcagaaaa ccggcggtga tcgccggttc ttccacgcag agatgaagat
    15901 ctgcaataaa gagtgtcgcc acgattactc gctaacggtc acgctttcaa tgataacgtc
    15961 ttcttttggc acgtcctggt gcataccgct acgaccggtt gccacacctt tgattttgtc
    16021 taccacgtcc atgccttcaa ccacttcagc aaatacgcag tagccccaac cttgcaggct
    16081 ttcgccagag aagttcagga agtcgttatc aaccacgttg atgaagaact gggcagttgc
    16141 agagtgcggt gcctgagtac gggccattgc cagcgtacca cgggtatttt tcagaccgtt
    16201 gttcgcttcg tttttgatcg ggtctttggt ggctttttgt ttcatgcccg gttcaaaacc
    16261 gccgccctga atcataaagc cgttgataac acggtggaaa atggtgttgt tgtaaaaacc
    16321 ttcgcggcag tagtccagga agtttttaac tgtttcaggt gctttatcgt caaaagtttt
    16381 gatgacaata tcgccgtgat tggtgtggaa agtaaccatt tttgcatcct gttccgtttg
    16441 attggtgctt caacccggtt cgggtcatat atagggtggt gttatagcat aaccgcacga
    16501 tcggatcatc tcgcaatgta tgctgattcg cgcgggaaat atgggtatta tacgcaactc
    16561 aattacccac acatgtctaa acggaatctt cgatgctaaa aatcttcaat actctgacac
    16621 gccaaaaaga ggaatttaag cctattcacg ccggggaagt cggcatgtac gtgtgtggaa
    16681 tcaccgttta cgatctctgt catatcggtc acgggcgtac ctttgttgcc tttgacgtgg
    16741 ttgcgcgcta tctgcgtttc ctcggctata agctgaagta tgtgcgcaac attactgata
    16801 tcgacgacaa aatcatcaaa cgcgccaatg aaaatggcga aagctttgtg gcgctggtgg
    16861 atcgcatgat cgccgaaatg cacaaagatt ttgatgcttt gaacattctg cgcccggata
    16921 tggagccgcg cgcgacgcac catatcgccg aaattattga actcactgaa caactgatcg
    16981 ctaaaggtca cgcttatgtg gctgacaacg gcgacgtgat gttcgacgtc ccgaccgatc
    17041 cgacatatgg cgtgctgtcg cgtcaggatc tcgatcagct gcaggcaggc gcgcgcgttg
    17101 acgtggtcga cgacaaacgc aacccgatgg acttcgttct gtggaaaatg tcgaaagagg
    17161 gcgaacctag ctggccgtct ccgtggggcg cgggccgtcc tggctggcac attgaatgtt
    17221 cggcaatgaa ctgcaagcag ctgggtaacc actttgatat ccacggcggc ggttctgacc
    17281 tgatgttccc gcaccacgag aacgaaattg cccagtccac ctgtgcgcac gatggccagt
    17341 atgtgaatta ctggatgcac tccggtatgg tgatggttga ccgcgagaag atgtctaaat
    17401 cgctgggtaa cttcttcacc gtgcgtgatg tgctgaaata ctacgatgcg gaaactgtgc
    17461 gttacttcct gatgtcgggt cactatcgca gtcagttgaa ctacagcgaa gagaacctga
    17521 aacaggcgcg tgcggcgctg gaacgtctct acactgcgct gcgcggcaca gacaaaaccg
    17581 ttgcgcctgc cggtggcgaa gcgtttgaag cgcgctttat cgaggcgatg aacgacgatt
    17641 tcaacactcc ggaagcctat tccgtactgt ttgatatggc gcgtgaagtg aaccgtctga
    17701 aagcagaaga tatggcagcg gcgaatgcaa tggcgtctca cctgcgtaaa ctttctgccg
    17761 tattgggcct gctggagcaa gaaccggaag cgttcctgca aagcggtgcg caggcagacg
    17821 acagcgaagt ggctgagatt gaagcgttaa ttcaacagcg tctggatgcc cgtaaagcga
    17881 aagactgggc ggcggcagat gcggcgcgtg accgtcttaa cgagatgggg atcgtgctgg
    17941 aagatggccc gcaagggacc acctggcgtc gtaagtaatt gcgctattgc cggatgcgag
    18001 ttttcgcatc cggttatcgt ctgcgccacc acaacattcc catcagtaac atccccggca
    18061 accacaccca catcaattca gaaataatca cctgatgccc gtacggcgtg gtgtaacgag
    18121 acaatgcaaa cggcgcgact ttaatcacct gccagggagc gaaaaagcgt tcatctgacc
    18181 acggccacag ccagccaacc catttaccgc cagtggttac cgaatccagc aagctgtgcg
    18241 atagcaacga gacggttaaa aacagccagc agcgaatcag cccagccctg aaccatcgac
    18301 gtccaatcag cacacataac agcgggacaa caaacgcaaa caccagcgaa tgggtaaacc
    18361 cgcgatgacc aaaaacattt ccgtaagcaa cgccaaattt aaacgacaat acatcggcat
    18421 cgggcagcat cgccaggatg attccggcaa ataacagacg cggagggatg gctttcgaac
    18481 ccaaccctaa accaatgcat aggggaacgg cggcgtgcgt aataacggtt ggcatgatgg
    18541 tcgcttcggc aaaatgtcga tgctatcagc atggatgaac ggggcgtaga gggcaaaagt
    18601 ctgaaaagag aaccggcctg ttgatacagg ccgggaaagg gatcaggcaa caacctgtac
    18661 gctgtgacct gcaaaactca ctgtctgacc ggcgacgatt ttgcagcgtt tgcgcgtttc
    18721 aaccgcaccg tcgactttca ccaggccttc ggctatcgcg attttcgcct gcgcgccgct
    18781 ttcgctccag ccttccagtt tcagcaagtc gcacagctca acgtgcggat gtttacctaa
    18841 agaaaatgtc gccatgttac tcaccctgtg gatcatgata ttcaacgcac gcctgtagcg
    18901 tgttttcaat cagcgtggca accgtcatcg ggccaacgcc gcccggaaca ggcgtaatgt
    18961 atgaggcgcg tttagccgcg tcttcaaaca cgacgtcgcc cacaactttg ccattttcca
    19021 gacggttgat gccgacatca atcacaattg cgccttcttt gatccagtca ccaggaataa
    19081 agcccggctt gccgacggca acgatcaaca aatcggcatt ttctacgtgg tgacgcagat
    19141 ttttagtgaa acggtgagtc acggtggtgg tgcaacctgc cagcagcagt tccatgctca
    19201 ttgggcgacc gacgatattc gatgcgccaa tcaccacggc gttaaggccg aaggtatcaa
    19261 tgttgtaacg ctcaagcagc gtgacgatac cgcgcggggt gcagggacgc agacgtggcg
    19321 cgcgctggca cagacgaccg acgttgtaag gatggaaacc gtccacgtct ttgtccggat
    19381 gaatacgttc cagcactttg acgttatcaa tacccgccgg taacggcagt tgaaccagaa
    19441 tgccatcaat ggtgttgtcg gcattcagcg catcgataag ctccagcagc tccgcttcgc
    19501 tggtggtttc cgggaggtca taagagcggg agacgaaccc gacttcttca caagccttgc
    19561 gtttgcttgc gacataaatt tgcgatgcag ggttgctacc caccagcaca acggccagtc
    19621 ctggcgcccg cagtccggct gcaatacgcg cctgaacttt ttgagcaact tcagagcgca
    19681 cctgctgcgc aatcgtttta ccgtcaataa tctttgctgc catcagagag aggattccat
    19741 ctgttacgta ggtcgaaggg gatgcgccta ttttgtcaga agcgtggcgc gctgtcagtt
    19801 ttcgttttct gaaaagtaaa accttctgta cctggctgat tcacacctat catgataacc
    19861 gtcgttggtt tgccgccata gtgagctaca tctgatgcgg tcgtacactt gttcagcaac
    19921 tggttcaaaa gccattgact cagcaagggt tgaccgtata attcacgcga ttacagcaca
    19981 ccgtggtatc aatgcgccct tagctcagtt ggatagagca acgaccttct aagtcgtggg
    20041 ccgcaggttc gaatcctgca gggcgcgcca ttaaaattca atcagttacg ccttctttat
    20101 ttcttctata attccagagt gggacattat caccaaaaat gtcgtctatt ttcctcgcgt
    20161 gctcagtcaa atgattaggc gcaaggtgag catatctacg aaccatttct ctggactccc
    20221 atccgcccat ttcctgaagc actgataatg ggacgcctga cggaatcaac ctgcttgccc
    20281 gggtatgcca gaggtcatgg aaacggaaat tttcaactcc tgcacgacga caagctgata
    20341 gccatgctgt cttgctgtca atgcgcatct tcctgagcgc aggcattgat gttccatctg
    20401 ctcgcttagc cgccctggta tgtacaccca catttgtgat gcttgcctgt ttgatcacgc
    20461 aacactttag aggcggtatc gttcagcgcc acaccaatgg cgcgatttga tttgctatct
    20521 tctggatcca ccctggcaac ttgtcgctgc atgtcaatct gttgccactc cagatttatg
    20581 atgttcgact ttctcagaac agttaccagc gcaaatttga cgacagattt cagtagttcg
    20641 gggctctcat caatcaggcg ttttgcctga ttcttttgta agtctcttgt gccattccac
    20701 ctcatacagg tttgcctgca aacagtaccg atattgcacc gccagatatt ccggctggct
    20761 tcgtggttgt tttcaacagt gatgaggcat cgtggcatct cgttgaagac catctgggta
    20821 aaacggttta tgacgtggca tcaggggacg cgttatttat ttctgaactc ggtccgttac
    20881 cggaaaatgt cacctggtta tccccggcag gggagtttca gaagtggaac ggcacatcat
    20941 ggataaagga tacggaggaa gaaacctcgt tgctggaagc ctggaagatg tatcgggtgt
    21001 tgctgaaccg agttgataca tcaactgccc ctgatattga gtggcctgtg aaccctgtca
    21061 gagagtaatc attgggatta tgccgcagca cgtcgtgcgc aagaacgtgc tgcgtctgga
    21121 tgctattttt tccctgaagc ggaaaacatt actacagtac ctttaacctt ggttttaaca
    21181 ttctcgaaat gctctgagag tatatgtgtt aagccttctt cggaatcttt tgtgtttgaa
    21241 aagatgcctt tctgattgta aatgcgcatc agtttttgac cgaagctatt gtgcacaact
    21301 ccatcgccaa gaattgtggc tccgtataga gttccatcgt cagttaaggc ctgcgccgca
    21361 ttgcgtatta cacagctttt tgtagatata tttccaggca ggcagtgaag aaggtaaaac
    21421 atggaaatgg aatcaaattg acc
//
LOCUS       DAPOXO010000086        21252 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPOXO010000086 DAPOXO010000000
VERSION     DAPOXO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21252
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.086"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            175..1149
                     /gene="hemB"
                     /locus_tag="ROH59_003911"
     CDS             175..1149
                     /gene="hemB"
                     /locus_tag="ROH59_003911"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDX4806338.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     gene            complement(1189..2040)
                     /gene="tauD"
                     /locus_tag="ROH59_003912"
     CDS             complement(1189..2040)
                     /gene="tauD"
                     /locus_tag="ROH59_003912"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HDX4806339.1"
                     /translation="MSERLSITPLGPYIGAQITGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIQTPPAGAILAAKELPSTGGDTLWASGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEAEHQRWREAVAKNPPLLHPVVRTHPVTGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     IPFYRAG"
     gene            complement(2037..2864)
                     /gene="tauC"
                     /locus_tag="ROH59_003913"
     CDS             complement(2037..2864)
                     /gene="tauC"
                     /locus_tag="ROH59_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HDX4806340.1"
                     /translation="MSVLINEILHSHRLKWRWPLSRQVTLSIGTLAVLLTVWWAVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRILLALLAAVLIGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            complement(2861..3628)
                     /gene="tauB"
                     /locus_tag="ROH59_003914"
     CDS             complement(2861..3628)
                     /gene="tauB"
                     /locus_tag="ROH59_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding subunit"
                     /protein_id="HDX4806341.1"
                     /translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKGIQGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEK
                     MQRLEIAHQMVKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     gene            complement(3641..4603)
                     /gene="tauA"
                     /locus_tag="ROH59_003915"
     CDS             complement(3641..4603)
                     /gene="tauA"
                     /locus_tag="ROH59_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4806342.1"
                     /translation="MAISSRNTFLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVATSQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDAWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
     gene            4909..5184
                     /gene="frmR"
                     /locus_tag="ROH59_003916"
     CDS             4909..5184
                     /gene="frmR"
                     /locus_tag="ROH59_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HDX4806343.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            5219..6328
                     /gene="frmA"
                     /locus_tag="ROH59_003917"
     CDS             5219..6328
                     /gene="frmA"
                     /locus_tag="ROH59_003917"
                     /EC_number="1.1.1.284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="HDX4806344.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFELARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            6421..7254
                     /gene="fghA"
                     /locus_tag="ROH59_003918"
     CDS             6421..7254
                     /gene="fghA"
                     /locus_tag="ROH59_003918"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDX4806345.1"
                     /translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAENEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPNLVMHHFPATARKSIAGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(7379..7918)
                     /locus_tag="ROH59_003919"
     CDS             complement(7379..7918)
                     /locus_tag="ROH59_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HDX4806346.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDSNLIKKI
                     FVDKLTQTQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(8020..9231)
                     /gene="mhpT"
                     /locus_tag="ROH59_003920"
     CDS             complement(8020..9231)
                     /gene="mhpT"
                     /locus_tag="ROH59_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter MhpT"
                     /protein_id="HDX4806347.1"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESTVFAGEKQAAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNSMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRMQPCADA"
     gene            complement(9407..10420)
                     /gene="dmpG"
                     /locus_tag="ROH59_003921"
     CDS             complement(9407..10420)
                     /gene="dmpG"
                     /locus_tag="ROH59_003921"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HDX4806348.1"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAVLKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGGDLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     gene            complement(10417..11367)
                     /gene="mhpF"
                     /locus_tag="ROH59_003922"
     CDS             complement(10417..11367)
                     /gene="mhpF"
                     /locus_tag="ROH59_003922"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="HDX4806349.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEENVAQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            complement(11364..12173)
                     /gene="mhpD"
                     /locus_tag="ROH59_003923"
     CDS             complement(11364..12173)
                     /gene="mhpD"
                     /locus_tag="ROH59_003923"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HDX4806350.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQHDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNETIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            complement(12183..13049)
                     /gene="mhpC"
                     /locus_tag="ROH59_003924"
     CDS             complement(12183..13049)
                     /gene="mhpC"
                     /locus_tag="ROH59_003924"
                     /EC_number="3.7.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /protein_id="HDX4806351.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARP"
     gene            complement(13067..14011)
                     /gene="mhpB"
                     /locus_tag="ROH59_003925"
     CDS             complement(13067..14011)
                     /gene="mhpB"
                     /locus_tag="ROH59_003925"
                     /EC_number="1.13.11.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxyethylcatechol 2,3-dioxygenase"
                     /protein_id="HDX4806352.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            complement(14013..15677)
                     /locus_tag="ROH59_003926"
     CDS             complement(14013..15677)
                     /locus_tag="ROH59_003926"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HDX4806353.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGLSRFPNVRCLFSRELEAFSQQDDEVTLHLKTEEG
                     QRETVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     gene            15868..16701
                     /gene="mhpR"
                     /locus_tag="ROH59_003927"
     CDS             15868..16701
                     /gene="mhpR"
                     /locus_tag="ROH59_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator MhpR"
                     /protein_id="HDX4806354.1"
                     /translation="MQNNEQTEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLH
                     RTTVRRLLETLLEEGYVRRSTSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLR
                     EVVWPTDVSTLDVDAMVVRETTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQE
                     RKELIEMLASRPGDDYQLAREPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLR
                     SEQRVIGCLNLVYMASAMTIEQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHL
                     R"
     gene            16778..17860
                     /gene="lacI"
                     /locus_tag="ROH59_003928"
     CDS             16778..17860
                     /gene="lacI"
                     /locus_tag="ROH59_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor LacI"
                     /protein_id="HDX4806355.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQACHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACANVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPITEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLPPNT
                     QTASPRALADSLMQLARQVSRLESGQ"
     gene            17983..21057
                     /gene="lacZ"
                     /locus_tag="ROH59_003929"
     CDS             17983..21057
                     /gene="lacZ"
                     /locus_tag="ROH59_003929"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HDX4806356.1"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPDADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPAENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFQVTTRFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPELWSAEIPNLYRAVVKLHTADGTLIEAEACDVGFL
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTSATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQYFQFRLSGRTIEVTSEYLFRHSDNEFLHWMVALDGKPLASGEVPLDVGPQGKQLIE
                     LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPSASHAIPQ
                     LTTSETDFCIELGNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGHGEMVVSVGVEVASDTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFNRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            21109..>21252
                     /locus_tag="ROH59_003930"
     CDS             21109..>21252
                     /locus_tag="ROH59_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806357.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGII"
BASE COUNT         4931 a         6039 c         5576 g         4706 t
ORIGIN      
        1 aataaaaatt aaaaatattt tcagtgaata tgaaattatt gctatttcta ttacaaagat
       61 gtcctgacct ctttttcatt ctcttcttgt caacatcgcg acaactttcg taaaacacac
      121 ccagcctgct tcaggtatac tatgcccctc gattccacaa acatcaggca gaccatgaca
      181 gacttaatcc aacgccctcg tcgcctgcgc aaatctcctg cgctgcgcgc tatgtttgaa
      241 gagacaacac ttagccttaa cgacctggtg ttgccgatct ttgttgaaga agaaattgac
      301 gactataaag ccgttgaagc catgccaggc gtgatgcgca ttccagagaa acatctggca
      361 cgcgaaattg aacgcatcgc caacgccggt attcgttccg tgatgacttt cggcatctct
      421 caccataccg atgaaaccgg cagcgatgcc tggcgggaag atggactggt ggcgcgtatg
      481 tcgcgcatct gcaagcagac cgtgccagaa atgatcgtta tgtcagacac ctgcttctgt
      541 gaatacacat ctcacggtca ctgcggtgtt ctgtgcgagc atggcgtcga caacgacgcg
      601 actctggaaa atttaggcaa gcaagccgtg gttgcagctg ctgcaggcgc agacttcatc
      661 gccccttctg ccgcgatgga tggtcaggta caggcgattc gccaggcgct ggacgctgcg
      721 ggctttaaag atacggcgat tatgtcgtat tcgaccaagt tcgcctcctc cttttatggc
      781 ccgttccgtg aagctgccgg aagcgcatta aaaggcgacc gcaaaagcta tcagatgaac
      841 ccaatgaacc gtcgtgaggc gattcgtgag tcactgctgg atgaagccca gggcgcagac
      901 tgcctgatgg ttaaacctgc cggagcatac ctcgacatcg tgcgtgagct gcgtgaacgt
      961 actgaattgc cgattggcgc gtatcaggtg agcggtgagt acgcgatgat taagttcgcc
     1021 gcgctggcgg gtgctataga tgaagagaaa gtcgtgctcg aaagcttagg ttcgattaag
     1081 cgtgcgggtg cggatctgat tttcagctac tttgcgctgg atttggctga gaagaagatt
     1141 ctgcgttaat gatcattatg ccgggttatc caacccggca tttccccctt accccgcccg
     1201 ataaaacgga atatccccaa gaatcgtcgc ccgatgcata atccgccgct gtggcaggta
     1261 atccgcattg gcatagtgct gagtcactcg gttatcccaa atcgcaatat cattcggttg
     1321 ccagcgccag cgcacctgaa actccggttt agtgatatgg gcaaacaaaa aacctaacaa
     1381 ggcttcgctc tctttctcgc tgacatcaac aattcgtgtg gtaaaacctt cgttcacaaa
     1441 cagtgcctgt ttaccggtca ccggatgcgt tcgcaccacc ggatgtagca acggtggatt
     1501 tttcgcgacc gcctcacgcc agcgttgatg ctcagcctcg gttttgcggt acttgtattc
     1561 cgggaacgat ttacggaaat catgctccgc acgcaacccg ctcaacagct ggcggaaggg
     1621 aacagagagc gcctcatatg cggcaatacc actggcccag agcgtatcgc cgccggtcga
     1681 gggtaactct ttcgccgcca gaatcgcccc tgcgggtggc gtttgaataa atgtcacatc
     1741 ggtgtgccag ttgtcgttat ccggcggatt atcattatgg gtatccagga cgatgatctc
     1801 gtcaacccct tcagcatgag ggtaaacagg gtgaatatgc agctcgccaa aacgctgggc
     1861 cagcgcgcgt tgctgctgcg gcgtgatagc ttgatcgcgc agaaacacca cctgatggcg
     1921 cagcaccgca tggtaaagct gttcaaactg attatcgctt aacgggcgcg ttaagtcggc
     1981 ccccgtaatt tgtgcgccaa tatacggccc cagcggggta atgctcagac gttcactcat
     2041 tgtacttctc catgccaggg cgtcaggcgg cgctgtaacg cgcgcagacc cagttctaaa
     2101 agaaaggcga taatcgcaat caccgcgatc cccgccagca ccacgtcagt cgcgagaaat
     2161 tcacccgctg actgaaccat aaatcctaaa ccgcgcgttg cggcaatcag ctccgccgcc
     2221 accagcgtag accagcccac acccagacca atgcgtaatc cggtgaggat ttccggcagc
     2281 gcgccgggca aaatgacaaa ccacagcacc tgcgcacggc tggcacccag cgactgggcg
     2341 gcacgaatgc gaacctgctg cgcgcttttc acccccgcca gcgccgacat cgccaccggc
     2401 gcaaaaatcg ctaaatagat cagcaagatc ttcgaggttt cgccaatacc aaaccagatc
     2461 accatcagcg gcaaataagc cagcggcggc accggacgat aaagctcgat tatcggatcc
     2521 agaatgccgc gcaccgtcgg gcttagcccc atggcgatcc cgaccggaat accgatcaac
     2581 accgccgcga gtagcgccag caaaatgcgc gtcaggctgg ctgccagatg ctgccacagc
     2641 gtggcgtcca taaatccctg cggcccggca atggtgagca gttttgccag tacctgttgc
     2701 ggtggcggca aaaacagcgg gctaatcagt tgcagcgccg cgactgccca ccatacagtg
     2761 agcaaaaccg ctaacgtacc aatgcttaag gtcacctgac gcgagagcgg ccagcgccat
     2821 ttcagccgat gcgaatgcag tatttcatta atgagcacac tcatgagaac gcctcccgtt
     2881 gctcaaatac gcggcttaaa acatattcgc gcatggcgat gaattgtgga tcggacttga
     2941 tgctgcggct cgactctccc gcaacaaagc ggcgagcaaa gttgagcggc agccgctcca
     3001 gcacacggcc tgggccgggt gaaagcaaaa ccagttcagt cgccataaac accgcttctt
     3061 ctatatcgtg ggtaatcaac agcacctgct ttcccgtctc ctgccaaagt ttcagcagca
     3121 gggtttgcat ctggtcgcgg gtgaaggcgt ccagcgcacc aaacggttcg tcgagtaata
     3181 acagctgggg atttgccgcc aacgcgcggg caatccccac ccgctgacgt tgaccaccgg
     3241 aaagctgcca gatgtagcgt ttttctgcgc cttccagccc gacttttttc accatctggt
     3301 gtgcgatttc cagtcgctgc attttctcta cacctgccag ttgcaggccg aacgccacgt
     3361 tgtcctgtac attgcgccac ggtaacaacc cttcattctg aaaaactacg ccacgctctg
     3421 ctcccggtcc ctgaataccc ttacccgcca gttgaatgct gccatgctga taaggcacaa
     3481 aaccagcaat caaattcagc aacgtagttt tgccgcagcc agacggcccc agaactacca
     3541 gaagctcgcc gctttccagc gtcaggttga tatcttccag tgccggtttg ccgccataat
     3601 cggcgtaaag atgagaaatt tgcagcatct gcgcctcctt ttattgcacg aagcgcgagg
     3661 taacgtactg gctgtaatca ttcgctacag ccgggacttt gccctgctct ttcaaaaact
     3721 gcgcggtgtc gatgatcgct ttgttcaccg gtccggtcag ttctgccgtt tgttgctgcg
     3781 gcgtcagata ggtattcccc ttcaccagcc ccggaacgtc accttccggc acgccgctta
     3841 accgcgccag tttgctgatg ttttccggct gtttcagcca cgcgtctggg ttagcaatgt
     3901 acggttgctg agcatcgatg gcgcttttag cgaacgcttt cacgacctca ggatgtttct
     3961 cggcaaaatc tttccgcacg acccagacgt ccagtgtcgg cgcgccccac tgcccgacct
     4021 gttcagaatc ggtcagcacc ttgccatctt tttccagggc gttaaccgcc ggtgcccata
     4081 cataagcacc atcaatatct ccccgctgcc atgcggcgat aattgcgggc ggctgcaggt
     4141 tcacaatctc aacttgccca ggtttaatac cccagtgttt cagcgccgcc agcaggctgt
     4201 agtgggtggt ggagataaac ggtacggcga tgcgtttacc aatcaagtct tccggtttac
     4261 tgatagtttt ctttaccacc agcgcttcgg agttacccag ttttgacgcc agcaagaaga
     4321 cttcaatcgg cacctgttgg ctggttgcaa ccgctaacgg gctggaaccg aggttgccga
     4381 tttgcacatc gcccgaagcc agcgcccgca cgatgctggc tccactgtca aacttacgcc
     4441 agtccacggt tgctccgctt tctttagcaa aggtgttgtc ggcctgagcc actttcgccg
     4501 gttcggcgga ggtttgatac gccacggtga cgttcaccgc ttgcgcctga aaagcgatga
     4561 atgccagtgc ggcaagaaat gtgttacgcg atgaaattgc catgattgtc tgctcccccg
     4621 tcttgttatg ggagcagtat ttcgttgcgg gtaagtttga taaaggaatt aaaacgtctt
     4681 gttaataaca aagcgttttt agaaaaaaat cggcaatggt tagcgagttt gcgcattttg
     4741 ctacttttaa caaacatcgc ctgatgtgac gctcacgcct cttatcatgc ctacaaatac
     4801 tggggccgga taaattttat tctccagtgt tatatactat aggggggtat gcattgacat
     4861 atagcatacc cccctatagt atattgcgtg cagatgatga ggtgcgaaat gcccagtact
     4921 ccggaagaga agaaaaaggt ccttactcga gttcgtcgta ttcgggggca gattgatgct
     4981 ctggaacggt cgctggaggg tgatgccgaa tgccgtgcca tactccaaca gatcgctgcc
     5041 gttcggggcg cggctaacgg actgatggca gaagtgcttg aaagccatat ccgggaaacg
     5101 tttgaccgaa atgactgcta cagccgtgaa gtcagccaat ccgttgacga cactattgaa
     5161 ctggttcgtg cctatcttaa atagctgaat ctattaccat attgaggaag agcgagagat
     5221 gaaatcacgt gctgccgttg catttgctcc cggtaaaccg ctggaaatcg ttgaaattga
     5281 cgttgcacca ccgaaaaaag gtgaagtgct gattaaagtc acccataccg gtgtttgcca
     5341 taccgacgca tttaccctct ccggcgatga cccggaaggt gtcttcccag tggttctcgg
     5401 tcacgaaggg gccggggttg tagttgaagt cggtgaaggc gtaaccagcg tcaaacctgg
     5461 cgaccatgtg atcccacttt acaccgcaga gtgcggcgag tgtgagtttt gtcgttctgg
     5521 caaaaccaac ctgtgtgtcg cggttcgcga aacgcagggc aaaggcttga tgccagacgg
     5581 caccacccgt ttttcttaca acgggcagcc gctttatcac tacatgggat gctcaacatt
     5641 cagtgaatac accgtggtag cggaagtgtc tctggccaaa attaatccag aagcaaacca
     5701 tgaacacgtc tgcctgctgg gctgtggcgt gaccaccggt attggcgcgg tacacaacac
     5761 agctaaagtc cagccaggtg attctgttgc cgtgtttggt cttggcgcga ttggtctggc
     5821 agtggttcag ggcgcgcgtc aggcaaaagc gggacggatt atcgctatcg ataccaaccc
     5881 gaagaaattc gaactggcgc gtcgcttcgg tgccaccgac tgcattaacc cgaatgacta
     5941 cgacaaaccg attaaagatg tcctgctgga tatcaacaaa tggggtatcg accatacctt
     6001 tgaatgcatc ggtaacgtca acgtgatgcg tgcagcgctg gaaagcgcgc accgcggctg
     6061 gggtcagtcg gtgatcatcg gggtagcagg ctccggtcag gaaatctcca cccgtccatt
     6121 ccagttggtc accggtcgcg tatggaaagg ttccgcgttt ggcggcgtga aaggtcgttc
     6181 ccagttaccg ggtatggttg aagatgcgat gaaaggtgat atcgatctgg aaccgtttgt
     6241 cacgcatacc atgagcctgg atgaaattaa tgacgccttc gacctgatgc atgaaggtaa
     6301 atccattcga accgtaattc gttactgatt tcccgctggt ttaccccgtc cagttcagat
     6361 ggggttctta atactctccc cgggcagccg tccgggggat taaccgtgag ataatgactg
     6421 atggaactca ttgaaaaaca tgccagcttt ggcggctggc aaaatgtgta tcggcattat
     6481 tcccaatcac tgaaatgtga aatgaatgtc ggcgtctatc tccccccaaa agccgagaat
     6541 gaaaaattgc cggtgttgta ctggctttca ggcctgacct gcaacgagca aaatttcatt
     6601 actaaatcgg ggatgcagcg ttacgcggct gagcacaaca ttattgttgt tgcgccggac
     6661 accagtccgc gaggcagtca tgtcgcagat gctgaccgtt acgatctcgg gcaaggtgcc
     6721 gggttttacc tgaacgcgac gcaagcgccg tggaatgaac attacaaaat gtatgactat
     6781 atccgcaacg agctgccgaa tttagtgatg catcattttc cggcaacggc cagaaagtca
     6841 atcgcaggtc attctatggg cgggctgggc gcgctggtgc tggcgttacg taacccagat
     6901 gaatatgtca gcgtctcggc gttttcgccc attgtctccc catcgcaagt accgtgggga
     6961 cagcaagcct ttgccgcata tcttggtgaa aataaagatg cctggttgga ttacgatccg
     7021 gtgagtctta tttcacaagg tcaacgcgtt gcggaaatca tggttgatca ggggttgagt
     7081 gatgattttt acgcggaaca actgcggact ccaaatcttg aaaagatctg ccaggagatg
     7141 aatatcaaga cgttaatccg ttatcacgag ggttatgatc acagctatta ttttgtctcc
     7201 agttttattg gcgagcatat tgcctaccac gccaataaac tgaatatgcg ttgagcatcc
     7261 gcgcacgcat gccggatgcg gcgtaaacct tatccggccc acatttcgct cgtaaaccgt
     7321 aggcctgata agacgcgaaa agcgtcgcat caggcatctg cacacgattt atcaatgttt
     7381 accacatcaa atcatcaggc actttgaagt cggcatacgg atcgtcttca tcctgctctt
     7441 cggcgctgag cgcgctgtgc aacacaatac tgctggcatc acgctgagca attttatcgg
     7501 caacgctggc gggaataatg gcgtattcac cttcgctatt gttatcgacc aacaagcggg
     7561 caatcgccag acgaccatta atcaactgcg tttgcgtgag cttatcgaca aaaatcttct
     7621 taatcagatt gctgtcagtg aagttaaaac caatatcgcc attggcaatg gtaattcggt
     7681 tcatttcaat gagctgcttc acctgggctt tatattcttt cgccaacgcc gcttgttttt
     7741 gttgctcgct aagctgttta tcacgctcaa gctgtgcctt tttattttct tctaccgccg
     7801 cccgtgcttc acgcgcctga acacgcgatt ttttcgccgt tctctcgacc ttcgccgctt
     7861 ttttgctggt gactagtccc gctttgagca actgctcttg taaggtaagt tttgccatct
     7921 ttgtttccaa acccgctgaa taatttttag cgagtatacc tgtaaacgcc gtaggtgtat
     7981 tgggggcaag tccctttcgc ccctgcttaa taaggcgcgt caggcatcgg cacacggctg
     8041 cattcttgat ctccgactca tcaaaataaa caccgccaac ccagcaacaa gaatacccgg
     8101 tgcagaagcg gccattacgc cgaccgtgcc agtgcctaat gccagcattt tcccggccag
     8161 taacggaccg ctcatagccc ccagacgccc taccgccacg gctgttccca cacctgttgc
     8221 gcggatctgc gaactgtaaa acaacggtgc cagagcatac aaaacgcttt gcccacctgt
     8281 cgcaaacaac cccgcgacaa atcccgccag caacatactg ttaaatgacg acaccgttcc
     8341 cagcgccagc agcgaagcta acatgccgct ataaatcagt agcgacatgg ttactggacg
     8401 cagtttatcc atcaatgcgc ccaacattaa cgtcccgctt gccgccccca tttgcagtgc
     8461 aaacatcacc cctgccgcct gcgatggctg gaatccttgc tccaccaaaa gcagcggcag
     8521 ccagttgatc aacatgtaga ccaccagcag agtgaaaaaa taacacaacc acagcagcag
     8581 cgtcgcggtt gccgtttctg gcgcaaataa cgcacgcagt ggtggcgcag cctgtttttc
     8641 gccagcgaaa accgtcgact ccggcagcca gcgcattaat agcggcacca gaatcaacgg
     8701 caccacacca cctacccaaa acaccgtttg ccatgctaag tttgcccccg cgaaacccag
     8761 cgtcgccgcc agcgccgcgc caatgggaac accgcaatac atcaggctca ctgccgtccc
     8821 acgaaaacgt ggtcccgcgg cttcagacgt cagggcgata agattcggca acgccgcccc
     8881 cagcccgaca ccggtcatca gccgcgcaaa gaccagtgag gggaaatccc atgcaatcgc
     8941 cgttgccagc gagaacaaac caaacagcgc aactgagcca atcaaaatac gcttacgccc
     9001 ataacggtct gccagcatcc cgccaaccag cgcgccgggt agcaaaccga gtattccggc
     9061 gctaaatatc cagcccattt gcattttatc gagtgcgaaa gcctgggcga tgccacccgc
     9121 cgcaatgcca gccgcctgaa gatccagccc ttccatcaga gcgaccaaaa aacaaagccc
     9181 gatggtcagc atcaggcggg atgaagatga tgaaggggta cgagtcgaca taagatgaac
     9241 ctcattgcga gtgcaggtga atcgcgactg atacattgcc agccgcgtaa tcagaactat
     9301 ttaatgactg cctacgggcg aaatgtaggc cggataaggc gttcacgccg catccggcag
     9361 tcgtgctggg atgggcatac aaaatgcacg ttctcggcag tcaatattat ttgttgttgc
     9421 gcagatccag cgccacgtcg acgatcatat cctcctggcc gccaaccatc cggcgtttgc
     9481 ccagctcaac gagaatatcc accgcgctta agccataacg cgccgccgcc gtttcacagt
     9541 gacgcaggaa gctggagtaa acaccagcgt atcccagcgc cagcgtttcg cgatcgactc
     9601 gtaccggtcg atcctgcaac ggacgcacca ggtcgtcagc ggcatccatt aacgcataga
     9661 gatcgccccc atgctgccaa cccagtttat ccgcggcggc aataaatact tccagcggcg
     9721 cgttacctgc gcccgcgccc attcccgcga ggctggcgtc gattcggtcg cagccctctt
     9781 ccaccgccgc gatagaattc gccacgccaa gactcaggtt atggtgagcg tgcatgccgg
     9841 tttgcgtttc tggtttcagc actgctttca gggcgcggaa acggtcacgg atatcgctca
     9901 tgttcatcgc accgccagaa tccaccacat aaatacaggt cgcaccgtag ccttccatca
     9961 gctttgcctg ctttgcgaga ttctccggcg tggtcatatg gctcatcatc agaaaaccaa
    10021 cggtgtccat tccgagctcg cgggcatact gaatatgctg ggcggaaaca tcagcctcgg
    10081 tacagtgcgt tgccacacga accacccgcg cgccagcctg ccaggcattt ttcagatcgt
    10141 gaatagtgcc gattcctggc agcaacaacg tcgcgatttt ggcgtgcttc accacatccg
    10201 ccgccgcttc aatccattca aggtcgctat gtgcgccgaa accatagtta aagctggaac
    10261 cctgcaaacc gtcgccgtgg gccacttcaa tcgaatccac gcgggcatca tccagtgctt
    10321 tggcaatctg gcggacattt tccagcgaat actgatgacg aatggcgtgc ataccgtcac
    10381 gcaacgtgac gtccgaaata taaagttttt taccgttcat gccgcttctc ctgccttgcg
    10441 cgccagtgac tgggccattt tttccgctgt cgccagcgca ctggaagtca taatgtcgag
    10501 gttgcccgca taggcaggca gataatgcgc tgcgccttcg acttccagcc agaccgccgt
    10561 tttcagcccg gagaactgcc ccacgcccgg taaattgacc ggtttatcct gcgggatgac
    10621 ttcaaactgc acgcgctgtt tcaggcgata acccggtacg taagcctgca ccgcctcagc
    10681 catttcattg attgaggctt cgatatcatc ttgtgaagct tcgtcgctca atacatacac
    10741 cgtgtcacgc atcatcaacg gtggctctgc tgggttaagc acaataatcg ccttcccttt
    10801 tgccgcgcca cccaccactt caatggcgcg cgaagtggtt tccgtaaatt catcgatgtt
    10861 ggcacgcgtg ccgggtccgg cagatttact ggcaatagaa gcgataattt cggcgtaatg
    10921 aacacgcgcc acgcgtgaaa ctgccgctac cattggaatg gtggcctggc cgccgcaggt
    10981 gaccatgttg acgttcagtt gagcgacgtt ctcctcgagg ttaaccaccg gcacgcagta
    11041 agggccgatg gcagcaggcg tcaggtcaat taagcgaata tccggtttcg cttcgcgcaa
    11101 agcggcatcg tttttcacat gcgcgcccgc gctggtcgca tcaaatacaa tgtcgatatc
    11161 agcaaattca ggcatgttca tcagcccgat caccccttca tgggtggtgg cgacgcccat
    11221 acgtctggca cgcgccagac cgtcggactg aggatcaatg ccgaccatca ccgccatctc
    11281 cagatgctga ccgtgacgca aaattttaat catcagatcg gtgccaatgt tgcctgaacc
    11341 gataatggcg actttacgct tactcatgac agacttcctt ttggggctgc gcttgaaaat
    11401 gtcgcagcaa ctgaacctat gccttcgata tgggcttcaa aacgatcgcc cgcattcacc
    11461 gccaccatcg gacctaatgc cccggtaaga atgatatctc cggcgcgcag cggttcaccc
    11521 agactggcca ttttgcgtgc cagccagacg gcggcattaa gcggatgtcc caggcattcg
    11581 ctgccgcgcc cgctggaaac ctcttcgtta ttacgcgtca tcttcatggc gcagtttttc
    11641 aggtctaacc ccgccgggcg ttgcgccgga ccgccgatga catacacccc gcaggaagcg
    11701 ttatctgcca cggtatcgac aaactgaatc gaccagtcgc gaatgcggct ccccaccacc
    11761 tccagcgccg gaagtaccca ttcaatggcg ttatacaatt cgtcgaaggt gatatcggtt
    11821 gcgggtagat cgcggttcaa caccagtgca atctccgctt caatgcgggg ttgcagaaca
    11881 cgggaaaaag gaatggtttc attatcgcca taacacatgt cggcaaataa tgtcccgaaa
    11941 tccggttgat caacgcccag ttgttgctgc actttcggat gcgtcagccc cactttgcgc
    12001 cccaccacgc gacgcccctg cgcaacgtca tgttgcacat tgatgtgctg aatggcgtag
    12061 gccgcttcag cgttatcgat accaatcaga tcgcgcagcg gcgcaatcgc ttcgccctgc
    12121 tctgcggcgc ggcgtaaatc cgccgccagt tgctcaagag tatgcttcgt catgaccgtt
    12181 ccttaagggc gtgcgaggaa attcagcacc agttgattga aagcgtcggc atgttcccac
    12241 tgcgcccagt gaccacagtc gcggaagata tgcagttcag aaccggcaat gccggacagc
    12301 agacgcagac ccgcatccat cggcacaaag cggtcgttgc gcccccagac aatcagggtt
    12361 tgcgctttga tttccgccag acgtgggcca aaatccggga actgtttcgg attggcttcc
    12421 aggctcttaa cgaagttttc caggtgatcg cggcgcgaca gcatattatt caggcgcgct
    12481 tcaaacaggg cgtcggtcaa atcgctggta tcaaaaacga agatatccat catcagcttc
    12541 aggttttcga tagtcggctg acgataaagc tgattcagtc gcttaatacc ttcggttggc
    12601 atcggcgtaa acaaactcat gccgcccgta ccgccgccca tcagcaccag tttgccgacg
    12661 cgctccggcc agttaagagt gaacgccaca gaactgtggc cacccatcga gttgcccagc
    12721 aggtggattt tggcgatatc cagttgatcc accacgcttt tcaggattcg cgcattaaga
    12781 tccgatcgcg aaccactatt aacgatcgaa tcgctcttac cccaacccgg acaatccagc
    12841 aggatcaccc gatagcccgc ctctaccagc ggatcgatat tgcggctgaa gttcgcccag
    12901 ccagtagcac ccgggccgga accatgcagc aggacaacgg tttcgtcgcc ttgtccgcag
    12961 tcattaaaat ggatgcgcag cgttttaccc gcttcttcta cattcagaaa acggctggtg
    13021 gcggcttcgg tttgtggctg ataactcatc atcttctcct gcatattcag ttctctgttc
    13081 tggcgcttaa cgagccaaat ccggcaatcc actccgggat tgggcggtaa taacgccctt
    13141 cgctacgcca gttgccaaac gcagaaatag cggcaaaagc ggcgacccag gttttgattt
    13201 catgtgtcga ctttccggca atggcggaaa gctcttcgtt actgacggca tccagttcct
    13261 gtatgcgtcc ctgctccagc aaagtcatga actggttatc ccaaatcggg ttgagcggat
    13321 gcagcgttct ctgatcctca acaaacttct cagcggcgct aatcacccgt tgctgacgca
    13381 attcgcgctc actggcgggt aaatctttcc cgctccccaa cagacggtcg cgcatatggg
    13441 catcggcttt cgccagttcg ggcaccggcg gctgatggga aagcccaccg gaacccagga
    13501 acagcacgcg tttattgaga gtactggtga aacgtccaat ggcttccccc aacatgcggg
    13561 tacgctggaa accgggcagc ggcgtggcga caccgttgat gaacaccggc agtactggca
    13621 ccttatccag cccaccgagc aggaactcca gcggctgggc gaacccgtgg tccacctgca
    13681 tacagtaaga aacggcaaga tcgatcccgc tcttcatgac ggcatgcgca caggcctccg
    13741 ccagctccac aggcacgggc agctctcctg ccgcactgcc gaaatcacca attgccgtcg
    13801 ctccaacgcc taaacagaac ggtggcatca cgtcatagaa aaagccgttg tagtgatctg
    13861 gcgcaaacag caccaccagt tcaggggaga aagccgcaat acgctcgcgg gcgctggcaa
    13921 tcacgccatt gacctcatcg agtacctctt gtgccgggtc gacatacccc accagcggcg
    13981 agtgggaaag acagtgaaga taagcgtgca tatcaggcta ccttttcgac agaaacgtcg
    14041 gcatcagggc gggtcagcgt catcaccgac gccagtttat tcagggtctt gcccagggtt
    14101 tgcggaatgg cggtggcggc aacaaagcga tccgggcgca tcaccaccag cgaagcattg
    14161 tgttgcgcga accagctacg caggcgacct tgcgtatccc ccacgcgtag tacgccgtcg
    14221 tggttatcct gtgcggtatg aatttgcact tccggcacca cctgaatgaa gcgtgtgccc
    14281 aacgcgcgcc actgctggat ttgctcgtcg ctcatccccc acagtggatt gcatccccag
    14341 ccaattaccg cgaagttcgc gccgatcgcg ttatcgagta gcgtcacgtc gccgttttcc
    14401 agcgtgactt tcggctgaat aaacatcttg ccgaccggag agtgcttcgc ttcgccctca
    14461 cgcaccagcg caccgccgta atattgcggc atcggcttga agcgcatttc gaggaagtag
    14521 cgttttactg gcggcagata attcagcagc caggaaacgc cgtcacgtaa cgtaccctgc
    14581 cagcgtttcg gcggagccag cacgttgccc gccgtcacgg acaggtcaat catcgctttg
    14641 gcgtgatcgc gacgttcttg ttgataggta tcgagcagcg catcgcgggc tttcccctgg
    14701 ataaccaacg ccagtttcca tgcgaggtta aaggcgtcgc gcataccact gttatagccc
    14761 tgcccctgcc acaccggcat gatgtgcgcg gcatcgcccg ccagcagtac gcgatcaata
    14821 cgaaaacgtt gcgccagtcg cgcgttgtgg gtgtagacac gctggcgaat caattcaaca
    14881 ttgtccggat taggcagcac tttgcttaac agcttgcgca tattttgcgg ctcacgcagc
    14941 tgttcttcgg tttctcccgg catcaccata aattcaaagc gacgtaccgc atgaggcagc
    15001 gcggcagaaa catacgggcg caccggatca caacacaaat agatatgcgg cgtacttaac
    15061 ggatcgttgg cgatatctac cacaatccac tgatttggcg cagttttacc ttcaaacggc
    15121 acattcaggg tgcgacggac aaaacttgcc ccaccatcac aggccaccag ccactgggct
    15181 ttgaccgttt cccgctgccc ttcttccgtt ttcaggtgca aggtcacttc gtcatcttgc
    15241 tggctgaagg cctccagctc gcgggaaaac aggcagcgca cattcggaaa acgcgacaat
    15301 ccttccagca tcaccgcatc gacctgaggc tgaataaagg cgttacggcg cggccagcca
    15361 aattcatcgg tcattggctg aatatcagca aaacagcgac cttttggggt gagaaaacgc
    15421 atcgcgtgcc acggcgtagt gtgcggcaga acattatcga ccaggccaac cgactgcatg
    15481 gtgcgcagcg cctcgtcatc aataccaatc gcacgcgggt agtcgatcaa cttatcgagt
    15541 ttctccacca ccagcacgtc aatgcccatc tggccgagat agttcgccat catcagcccg
    15601 accggaccgg caccagcgat cgccacctga acgctatggt taacagcagg ctggatgtca
    15661 gggtgttgta ttgccatttc agtacctcac gactcggaca aaatgccgtt gcgcgcacag
    15721 tacagcgcaa cttattttgt taaaaacatg taaatgattt tttattgtgc gctcagtata
    15781 ggaagggtgt tttcggctac aatcaaaaca tgcccgaatg tgcaccaggt gcacaacgtt
    15841 gttttaacta tataaatgtc aattaatatg cagaacaatg agcagacgga atacaaaacc
    15901 gtgcgcggct taacccgcgg tctaatgtta ttaaatatgt taaataaact tgatggcggt
    15961 gccagcgtcg ggctgctggc ggaactcagc ggcctgcatc gcaccactgt gcggcgactg
    16021 ctggagacgt tactggaaga gggatatgtc cggcgcagta cctccgatga cagttttcgt
    16081 ctgaccatca aagtgcggca attaagcgaa ggatttcgtg acgaacagtg gatttctgca
    16141 ctggcggccc cgctgctggg cgatctgttg cgcgaagtgg tatggccgac agatgtgtcc
    16201 acgctggatg ttgatgcaat ggtggtacgc gaaaccaccc atcgtttcag ccgcttatct
    16261 tttcaccggg caatggtcgg gcgacggtta ccgcttctga aaaccgcctc gggcctgacc
    16321 tggctggcct tttgcccgga acaagaacgc aaggaattaa tcgagatgtt agcctcccgc
    16381 cccggtgatg actatcaact ggcacgagaa ccgttaaagc tggaagccat tctggcgcgc
    16441 gcgcgcaaag aggggtacgg acagaactac cgcggctggg atcaggagga gaagatcgcc
    16501 tctatcgccg taccgctgcg cagtgaacaa cgggtgattg gctgtctgaa tctggtgtat
    16561 atggcgagcg caatgaccat cgaacaggca gcggaaaagc atcttccggc gctgcaacgg
    16621 gtggcaaaac agatcgaaga aggggttgaa tcgcaggcta ttctggtagc gggaaggcga
    16681 agcggcgtgc atttacgctg acaccatcga atggcgcaaa acctttcgtg gtatggcatg
    16741 atagcgcccg gaagagagtc aattcagggt ggtgaatgtg aaaccagtaa cgctatacga
    16801 tgtcgcagag tatgccggtg tctcttatca gaccgtttcc cgcgtggtga accaggcctg
    16861 ccacgtttca gcgaaaacgc gggaaaaagt ggaagcggcg atggcggagc tgaattacat
    16921 tcccaaccgc gtggcacaac aactggcggg caaacagtcg ttgctgattg gcgttgccac
    16981 ttccagtctg gccctgcacg cgccgtcgca aattgttgcg gcgataaaat ctcgcgccga
    17041 tcaactgggt gccagcgtgg tggtgtcgat ggtagaacga agcggcgtcg aagcctgtaa
    17101 agcggcggtg cacaatcttc tcgcgcaacg cgtcagtggg ctgatcatta actatccgct
    17161 ggatgaccag gatgccattg ctgtggaagc tgcctgcgct aatgttccgg cgttatttct
    17221 tgatgtctct gaccagactc ccatcaacag tattattttc tcccatgaag acggtacgcg
    17281 actgggcgtg gagcacctgg tcgcattggg tcaccagcaa atcgcgctgt tagcaggccc
    17341 attaagttct gtctcggcgc gtctgcgtct ggcgggctgg cataaatatc tcacacgcaa
    17401 tcaaattcag ccgataacag aacgggaagg cgactggagt gccatgtccg gttttcaaca
    17461 aaccatgcaa atgctaaatg agggcatcgt tcccactgcg atgctggttg ccaacgatca
    17521 gatggcgctg ggcgcaatgc gcgccattac cgagtccggg ctgcgcgttg gtgcggatat
    17581 ctcggtagtg ggatacgacg ataccgaaga cagctcgtgt tatatcccgc cgttaaccac
    17641 catcaaacag gattttcgcc tgctggggca aaccagcgtg gaccgcttgc tgcaactctc
    17701 tcagggccag gcggtgaagg gcaatcagct gttgcccgtc tcactggtga aaagaaaaac
    17761 cacccttccg cccaatacgc aaaccgcctc tccccgcgcg ttggccgatt cattaatgca
    17821 gctggcacga caagtttccc gactggaaag cgggcagtga gcgcaacaca attaatgtga
    17881 gtcagctcac tcattaggca ccccagtctt tacactctat gtgtccggct cgtatgttgt
    17941 gtgaaattgt gagcggataa caatttcaca caggatacag ctatgactat gattacggat
    18001 tctctggccg tcgtattaca acgtcgtgac tgggaaaacc ctggcgttac acaacttaat
    18061 cgccttgcgg cacatccccc tttcgccagc tggcgaaata gcgaagaggc ccgcaccgat
    18121 cgcccttccc aacagttgcg cagcctgaat ggcgaatggc gctttgcctg gtttccggca
    18181 ccagaagcgg tgccggaaag ctggctggag tgcgatcttc ctgacgccga tactgtcgtc
    18241 gtcccctcaa actggcagat gcacggttac gacgcgccca tctacaccaa cgtaacctat
    18301 cccattacgg tcaatccgcc gtttgttccc gcggagaatc cgacaggttg ttactcgctc
    18361 acatttaatg ttgatgaaag ctggctacag gaaggccaga cgcgaattat ttttgatggc
    18421 gttaactcgg cgtttcatct gtggtgcaac gggcgctggg tcggttacgg ccaggacagc
    18481 cgtttgccgt ctgaatttga cctgagcgca tttttacgcg ccggagaaaa ccgcctcgcg
    18541 gtgatggtgc tgcgctggag tgacggcagt tatctggaag atcaggatat gtggcggatg
    18601 agcggcattt tccgtgacgt ctcgttgctg cataaaccga ccacgcaaat cagcgatttc
    18661 caagttacca ctcgctttaa tgatgatttc agccgcgcgg tactggaggc agaagttcag
    18721 atgtacggcg agctgcgcga tgaactgcgg gtgacggttt ctttgtggca gggtgaaacg
    18781 caggtcgcca gcggcaccgc gcctttcggc ggtgaaatta tcgatgagcg tggcggttat
    18841 gccgatcgcg tcacgctacg cctgaacgtt gaaaatccgg aactgtggag cgccgaaatc
    18901 ccgaatctct atcgtgcggt ggttaaactg cacaccgccg acggcacgct gattgaagca
    18961 gaagcctgcg atgtcggttt cctcgaggtg cggattgaaa atggtctgct gctgctgaac
    19021 ggcaagccgt tgctgattcg cggcgttaac cgtcacgagc atcatcctct gcatggtcag
    19081 gtcatggatg agcagacgat ggtgcaggat atcctgctga tgaagcagaa caactttaat
    19141 gccgtgcgct gttcgcatta tccgaaccat ccgctgtggt acacgctgtg cgaccgttac
    19201 ggcctgtatg tggtggatga agccaatatt gaaacccacg gcatggtgcc aatgaatcgt
    19261 ctgaccgatg atccgcgctg gctacccgcg atgagcgaac gcgtaacgcg gatggtgcag
    19321 cgcgatcgta atcacccgag tgtgatcatc tggtcgctgg ggaatgagtc aggccacggc
    19381 gctaatcacg acgcactcta tcgctggatc aaatctgtcg atccttcccg cccggtacag
    19441 tatgaaggcg gcggagccga cacctccgca accgatatta tttgcccgat gtacgcgcgc
    19501 gtggatgaag accagccctt cccggcggtg ccgaaatggt ccatcaaaaa atggctttcg
    19561 ctgcctggag aaatgcgccc gctgatcctt tgcgaatatg cccacgcgat gggtaacagt
    19621 cttggcggct tcgctaaata ctggcaggcg tttcgtcagt acccccgttt acagggcggc
    19681 ttcgtctggg actgggtgga tcagtcgctg attaaatatg atgaaaacgg caacccgtgg
    19741 tcggcttacg gcggtgattt tggcgatacg ccgaacgatc gccagttctg tatgaacggt
    19801 ctggtctttg ccgaccgcac gccgcatccg gcgctgacgg aagcaaaaca ccaacagcag
    19861 tatttccagt tccgtttatc cgggcgaacc atcgaagtga ccagcgaata cctgttccgt
    19921 catagcgata acgagttcct gcactggatg gtggcgctgg atggcaagcc gctggcaagc
    19981 ggtgaagtgc ctctggatgt tggcccgcaa ggtaagcagt tgattgaact gcctgaactg
    20041 ccgcagccgg agagcgccgg acaactctgg ctaacggtac gcgtagtgca accaaacgcg
    20101 accgcatggt cagaagccgg acacatcagc gcctggcagc aatggcgtct ggcggaaaac
    20161 ctcagcgtga cactcccctc cgcgtcccac gccatccctc aactgaccac cagcgaaacg
    20221 gatttttgca tcgagctggg taataagcgt tggcaattta accgccagtc aggctttctt
    20281 tcacagatgt ggattggcga tgaaaaacaa ctgctgaccc cgctgcgcga tcagttcacc
    20341 cgtgcgccgc tggataacga cattggcgta agtgaagcga cccgcattga ccctaacgcc
    20401 tgggtcgaac gctggaaggc ggctggccat taccaggccg aagcggcgtt gttgcagtgc
    20461 acggcagata cacttgccga cgcggtgctg attacgaccg cccacgcgtg gcagcatcag
    20521 gggaaaacct tatttatcag ccggaaaacc taccggattg atggacacgg cgagatggtc
    20581 gtcagtgtag gtgttgaagt agcgagcgat acaccgcatc cggcgcggat tggcctgacc
    20641 tgccagctgg cgcaggtcgc agagcgggta aactggctcg gcctggggcc gcaagaaaac
    20701 tatcccgacc gccttactgc agcctgtttt aaccgctggg atctgccatt gtcagacatg
    20761 tataccccgt acgtcttccc gagcgaaaac ggtctgcgct gcgggacgcg cgaattgaat
    20821 tatggcccac accagtggcg cggcgacttc cagttcaaca tcagccgcta cagccaacaa
    20881 caactgatgg aaaccagcca tcgccatctg ctgcacgcgg aagaaggcac atggctgaat
    20941 atcgacggtt tccatatggg gattggtggc gacgactcct ggagcccgtc agtatcggcg
    21001 gaattccagc tgagcgccgg tcgctaccat taccagttgg tctggtgtca aaaataataa
    21061 taaccgggca ggccatgtct gcccgtattt cgcgtaagga aatccattat gtactattta
    21121 aaaaacacaa acttttggat gttcggttta ttctttttct tttacttttt tatcatggga
    21181 gcctacttcc cgtttttccc gatttggcta catgacatca accatatcag caaaagtgat
    21241 acgggtatta tt
//
LOCUS       DAPOXO010000087        21145 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPOXO010000087 DAPOXO010000000
VERSION     DAPOXO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21145
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.087"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            126..728
                     /locus_tag="ROH59_003931"
     CDS             126..728
                     /locus_tag="ROH59_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDX4806358.1"
                     /translation="MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNK
                     TLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFD
                     LYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNEIYSAIKDLQRKAPDKNIVIFTHNH
                     CLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH"
     gene            complement(767..1192)
                     /gene="nudI"
                     /locus_tag="ROH59_003932"
     CDS             complement(767..1192)
                     /gene="nudI"
                     /locus_tag="ROH59_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HDX4806359.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGE
                     RIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSAN
                     RDVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL"
     gene            1471..2013
                     /locus_tag="ROH59_003933"
     CDS             1471..2013
                     /locus_tag="ROH59_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806360.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTEST
                     GLALSGNWTHNDDDGDAAGVGLGLNLPLGPLMATVGGKGVYTNPNDGDEGYAAAVGGG
                     LQWQIGDSFRLFGEYYYSPDSLSSGIKSYEEANAGARYTIMRPVSIEAGYRYLNLAGK
                     NGNRDNAIADGPYVGVNASF"
     gene            2113..3315
                     /locus_tag="ROH59_003934"
     CDS             2113..3315
                     /locus_tag="ROH59_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HDX4806361.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAIQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEEQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQSRQFSLTLSEQF
                     TGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGLEDEH
                     LNFALATPDGTFALRVHFSATRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     VESMTLSV"
     gene            3535..4317
                     /locus_tag="ROH59_003935"
     CDS             3535..4317
                     /locus_tag="ROH59_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDX4806362.1"
                     /translation="MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYL
                     LLNELRRQRFLSLDHQENFCLWTRLVELSGHALSKMDLRELARPRLTQLMDTTGLLCH
                     LGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
                     VWERATPTTITHPQRLYEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAIS
                     VVGTRLQINEEYRDYLAGKAIACARDISRLLGWKSPFDLQAS"
     gene            4332..5537
                     /gene="rhmD"
                     /locus_tag="ROH59_003936"
     CDS             4332..5537
                     /gene="rhmD"
                     /locus_tag="ROH59_003936"
                     /EC_number="4.2.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HDX4806363.1"
                     /translation="MTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATP
                     MSKYREYEQSRQSFGINVLGTLIVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEG
                     KCVSDIKLIHDQMLNATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAV
                     RDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFW
                     LMLDCWMSQDVNYATKLAHACAPYNLKWIEECLPPQQYEGYRELKHNAPAGMMVTSGE
                     HHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHA
                     VITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRD
                     CNLKRPYSH"
     gene            5594..6883
                     /locus_tag="ROH59_003937"
     CDS             5594..6883
                     /locus_tag="ROH59_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416749.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806364.1"
                     /translation="MSTALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQI
                     DTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWAD
                     TEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
                     GALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPGQARFLSKQEKTLLINQ
                     LASEEQQKVTSRLSDALRNGRVWQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFT
                     ASVVTAIPWVAALFGTWLIPRYSDKTGERRNVAALTLLAAGIGIGLSGLLSPVLAIVA
                     LCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFS
                     SDAAGLLTLAAVAVIGSLIIFTLRVNRTVAQTDVAHH"
     gene            6901..7704
                     /gene="yfaU"
                     /locus_tag="ROH59_003938"
     CDS             6901..7704
                     /gene="yfaU"
                     /locus_tag="ROH59_003938"
                     /EC_number="4.1.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-L-rhamnonate aldolase"
                     /protein_id="HDX4806365.1"
                     /translation="MNALLTNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLL
                     IDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTA
                     DQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDN
                     LDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAV
                     APDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRVKGSY"
     gene            complement(7745..7978)
                     /locus_tag="ROH59_003939"
                     /pseudo
     CDS             complement(7745..7978)
                     /locus_tag="ROH59_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7979..8974)
                     /locus_tag="ROH59_003940"
     CDS             complement(7979..8974)
                     /locus_tag="ROH59_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HDX4806366.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSEGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGEASPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRDFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIQEIAERSPLQKERLMTIAERLRQEGHQIGWQEGKIEGWQEGKLEGLQ
                     QGKLEGLQKGKLEGLQEGMHEQAIKIALRMLEQGFEREIVLAATQLTDADIPNCH"
     gene            complement(9167..10357)
                     /gene="glpC"
                     /locus_tag="ROH59_003941"
     CDS             complement(9167..10357)
                     /gene="glpC"
                     /locus_tag="ROH59_003941"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HDX4806367.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMDTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            complement(10354..11613)
                     /gene="glpB"
                     /locus_tag="ROH59_003942"
     CDS             complement(10354..11613)
                     /gene="glpB"
                     /locus_tag="ROH59_003942"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HDX4806368.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELDLKVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWHWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERDGIREPILGLD
                     VLQTATRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAGQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            complement(11603..13231)
                     /gene="glpA"
                     /locus_tag="ROH59_003943"
     CDS             complement(11603..13231)
                     /gene="glpA"
                     /locus_tag="ROH59_003943"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HDX4806369.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGAAVCGVRVRNHLTGEIQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYN
                     EIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            13504..14862
                     /gene="glpT"
                     /locus_tag="ROH59_003944"
     CDS             13504..14862
                     /gene="glpT"
                     /locus_tag="ROH59_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HDX4806370.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRN
                     GG"
     gene            14867..15943
                     /gene="glpQ"
                     /locus_tag="ROH59_003945"
     CDS             14867..15943
                     /gene="glpQ"
                     /locus_tag="ROH59_003945"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDX4806371.1"
                     /translation="MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRI
                     KNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDVL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            16146..16796
                     /gene="inaA"
                     /locus_tag="ROH59_003946"
     CDS             16146..16796
                     /gene="inaA"
                     /locus_tag="ROH59_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HDX4806372.1"
                     /translation="MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYARHAVSPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIY
                     VKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(16850..17104)
                     /gene="yfaE"
                     /locus_tag="ROH59_003947"
     CDS             complement(16850..17104)
                     /gene="yfaE"
                     /locus_tag="ROH59_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HDX4806373.1"
                     /translation="MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(17104..18234)
                     /gene="nrdB"
                     /locus_tag="ROH59_003948"
     CDS             complement(17104..18234)
                     /gene="nrdB"
                     /locus_tag="ROH59_003948"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HDX4806374.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL"
     gene            complement(18323..20608)
                     /gene="nrdA"
                     /locus_tag="ROH59_003949"
     CDS             complement(18323..20608)
                     /gene="nrdA"
                     /locus_tag="ROH59_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HDX4806375.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
BASE COUNT         4944 a         5174 c         5641 g         5386 t
ORIGIN      
        1 aattttgagg cattttgccg gcatcatagg atttttaata ttacaccaac tgctaattat
       61 cgccagaaaa gtcgctcaat ttcacggtaa ttgtctggtt gcgcttgtct acaggtggag
      121 tttacgtgtt agctttttgc cgatcttcgt tgaagtcaaa aaaatatttc atcattttac
      181 tggcgctcgc tgcaattgcc ggactgggga ctcatgccgc ctggagtagc aatggtttgc
      241 cacgcatcga caataaaaca ctggccagac tggcacagca gcacccggtt gtcgttttgt
      301 ttcgccatgc tgaacgttgc gatcgttcaa ccaatcaatg cttgtcagat aaaacaggta
      361 ttacggtcaa aggtacccag gatgcccgtg aactgggcaa cgcttttagt gctgatatcc
      421 ctgattttga tctctattcc agtaataccg tccggactat tcagtcggcg acctggtttt
      481 cggcgggtaa aaagctgacg gtagataaac gatttcttca atgcggtaat gagatttata
      541 gtgcaattaa agacttacaa cgcaaagcac ctgataaaaa tatcgttatt tttacccata
      601 atcattgcct gacatatatt gctaaagata agcgtgatgc gacatttaaa cctgattatc
      661 tggatggttt agtcatgcat gtggaaaaag gcaaagttta tctggatggg gaattcgtta
      721 accactaaat tttcaatctg acagccagtg atggctgtca tcattgttaa agaagacctt
      781 tcaaacgtaa cgtttttcgg gtggcaacat tcaaatcata atgcaccaga tcttcaggtt
      841 ttacccacgc gtagtcctga aactcttcgt ttattttcac atctcggttg gcagaaacgc
      901 agtcaaaaat caggtaaatc atataaatct cttccttgcg accatctgca tacgtcttgg
      961 tgcgaatatc atcgctgaag gtccacggcg tgatttctgt caaaagcagc tgttctccca
     1021 gttcttcgcg aatttcgcgg cgtagtgcct cttcaattcg ttcgccaggc tccacgccgc
     1081 cacccgaaag cgcccattga ccggggaaaa cgccgcgatc gtcggccatt ttacacagca
     1141 aataagcacc atcattttga atcaaagggc atacaatagt ccgttgtcgc acaggggtat
     1201 tccttataaa taaaaagaaa ccatgagaat acggtaactc agaaatatgt gaaagtgaca
     1261 gtaatctctt ttgcgatgat aactacattt attattattt ttgtgtgtat cgataaagtg
     1321 tgtttatttt ttcggcgttt aattatttaa gaagtattta gttacaataa gtgactagat
     1381 cccttttttc gctcattgaa tcctctgcgc caggcagtac aatcccgcag ctttgggaat
     1441 tttgattaat tgcttgtggg aaagaggata atgaaaaaaa ttgcgctagc aggtctggcc
     1501 ggaatgctgt tggtttctgc atcggtcaat gcaatgagca tcagcggcca ggcgggtaaa
     1561 gaatacacca atattggtgt cggttttggg actgaatcga cgggcctggc gttaagcggt
     1621 aactggacac ataacgacga cgacggtgat gccgcgggcg tggggctggg gttgaatctg
     1681 cctctcgggc cattaatggc gaccgttggc ggaaaaggcg tttacaccaa cccgaacgat
     1741 ggtgatgaag gttatgcagc ggcagttggc ggtggtttgc agtggcaaat tggtgacagc
     1801 ttccgcttgt ttggtgagta ttactactct ccggattcgc tctccagcgg aattaaaagt
     1861 tatgaagaag cgaatgctgg cgcgcgttac accattatgc gtccagtcag cattgaggct
     1921 ggctaccgtt acctgaacct ggcaggtaaa aatggcaatc gtgataacgc cattgctgat
     1981 ggtccgtatg ttggggtaaa tgccagcttc tgacgccttc cggcgcggcg ttctgtcgcg
     2041 ccattcagtt tcttactacg ccctgtctcc ctttgcgtta tagtgattcg ataacaaaag
     2101 caggagataa ccatgttaaa agtggaaatg ttatccaccg gggatgaagt gttacacggg
     2161 caaatcgttg acactaacgc tgcctggctg gccgattttt tctttcatca ggggctgcca
     2221 ttatctcgcc gcaatacggt gggggataac cttgatgact tagtcaccat tcttcgcgaa
     2281 cgtagtcagc acgccgatgt gttgatcgtt aacggcgggc tgggaccgac cagtgatgat
     2341 ttaagcgcac tcgccgctgc gacagcaaaa ggtgaaggcc tggtgctgca tgaagcctgg
     2401 ctcaaagaga tggaacgcta tttccatgaa cggggacgag taatggcacc gagcaaccgt
     2461 aaacaagcgg agctgcctgc cagtgctgaa tttatcaata acccggtagg cactgcctgt
     2521 ggttttgcca tacagcttaa tcgttgcctg atgttcttta cccccggcgt accgtcagaa
     2581 tttaaggtga tggtcgagca cgaaatcctg ccgcgcctgc gcgagcgttt ttctttacca
     2641 cagccgccgg tttgcctgcg tttgactacc tttggtcgtt cggaaagcga tctggcacaa
     2701 agcctggaca ctctacaact gccgccgggc gtaacaatgg gctatcgctc ctcaatgccg
     2761 attatcgaac tgaaactcac cggaccggca agcgaggaac aggcgatgga aaaactgtgg
     2821 ctggacgtta aacgtgttgc cggacagagc gtgattttcg aaggcaccga aggactgccc
     2881 gcgcagatca gtcgcgaatt gcagagccgc cagttcagcc tgacgctgag cgagcaattc
     2941 accggtggtt tattggcttt gcaactttct cgcgcaggtg ctccattgct ggcgtgtgaa
     3001 gtggttcctt cacaggagga aaccctggcg caaactgcgc actggattac agaacggcgg
     3061 gcgaaccatt ttgctgggtt ggcactggct gtttctggtc tggaagatga gcatctcaac
     3121 tttgcactag ccacgccaga cggcactttc gctttgcgtg tacatttcag tgccacacgc
     3181 tacagtctgg ctattcgcca ggaagtgtgc gcaatgatgg cgcttaatat gctacgccgt
     3241 tggttaaacg gccaggacat cgccagcgag catggctgga ttgaggttgt tgagtccatg
     3301 accttatctg tctgattccg ccactctgtg ccggtttact gcaccggcac attccccctc
     3361 cggcaaaatt tgtccaacct gttgtactca ataagaaaaa atccgtgcgc tgattcacaa
     3421 atttgtgcgt aatttctcca gtccgctgga cgagaaacgg gatttgatgc gcttcacaat
     3481 tttactcccc ctgaacaacg agactgattc cagtatctaa gactggagtc cagtatgttg
     3541 gaatcaagca aagttcccgc cctgacacgg gctattgata ttctcaattt gattgcccgg
     3601 attggcccct gtagtgctgc gacgatcatt gacacattgg ggatccctaa aagcacagcc
     3661 tatttgctgc ttaatgaact caggcgtcag cgttttctta gccttgatca ccaggaaaat
     3721 ttttgtttgt ggaccaggct ggtggagctt tccggtcatg cgttaagcaa gatggatctc
     3781 cgggaactgg ctcgaccgcg tttgacgcaa ctgatggata ccaccgggct gttatgtcac
     3841 ctggggatta ttgataacgg cagcgcttat tacattttga aagtggagtc atcagccact
     3901 atcagcgtgc gttcccatga aggaaaaagc ctttcgcttt atcgctccgg aataggtaaa
     3961 tgcctgcttg cctggcaacc tgcagctgta cagcaaagta ttatcgaagg gctggtctgg
     4021 gaacgggcga cacccacaac gattactcat ccacaacggc tctacgaaga actggcgcgt
     4081 attcgccgcc agggctggag ctatgacaac ggcgaagatt acgccgatgt ccgttgtgtc
     4141 gctgcgccgg tgtttaacgc caataacgag cttaccgctg cgatttcggt ggtcggtacc
     4201 cgcttacaaa tcaatgaaga ataccgtgat tatctggcgg gcaaggccat tgcctgtgcc
     4261 agggatattt cacgtttgtt gggatggaaa agtccctttg acttacaggc ctcataacaa
     4321 tggagaacat catgacccta ccaaaaatca aacaggttcg cgcctggttt actggcggtg
     4381 cgacagcaga aaaaggcgct ggcggcggtg attatcacga ccagggggcg aatcactgga
     4441 ttgatgatca tattgccacc ccgatgagta aataccgcga atacgagcag tcccgccagt
     4501 catttggcat taacgttctt ggcacgttga ttgttgaagt tgaagcagaa aacggccaga
     4561 ccggattcgc tgtttcgaca gccggtgaaa tgggctgttt tattgtcgaa aaacatctta
     4621 accgtttcat tgagggtaaa tgcgtcagtg atatcaaact gatccacgat caaatgctca
     4681 atgccaccct gtattactcc ggctctggtg gcctggtgat gaatacgatt tcctgtgtcg
     4741 atctggctct gtgggatctg ttcggcaaag tggtcgggct tccggtttat aaacttttag
     4801 gcggcgctgt tcgtgatgag attcagttct acgccacagg tgcgcgtccg gatctggcaa
     4861 aagagatggg ctttatcggt ggcaaaatgc cgacgcactg ggggccacat gatggcgatg
     4921 cggggatccg caaagatgcc gctatggtcg cggatatgcg tgaaaaatgc ggtgaggatt
     4981 tctggttaat gctcgactgc tggatgagtc aggacgtgaa ttatgccacc aaactggccc
     5041 acgcttgcgc gccctataac ctgaaatgga tcgaagagtg cctgccgcca cagcagtatg
     5101 aaggttatcg cgaactgaaa cacaacgcac cagcggggat gatggtcacc agcggtgagc
     5161 accacggcac actgcaatct ttccgtacgc tttcagaaac cggtatcgac attatgcagc
     5221 cggatgttgg ctggtgcggt ggcttaacca cgctggtgga aattgccgca atcgccaaat
     5281 ccagggggca actggtggtg ccacacggtt cgtctgttta ctcccaccat gcggtgatca
     5341 ccttcaccaa tacgccattc agcgaattcc tgatgaccag cccggattgt tcaacgatgc
     5401 gtccgcaatt tgatccgatt ctgcttaatg agccagtacc ggtgaatggt cgtattcata
     5461 aatcagtgct tgataaaccc ggtttcggcg tcgaactcaa tcgtgactgc aatttgaaac
     5521 gcccctacag ccactaatca ctccgggcgt tgctgtgaca acggtaacgc ccacatattc
     5581 taaggagctt tttatgagca ccgctttgct tgacgccgtg gtgaagaaaa accgcgcgcg
     5641 tttaattccg tttatgttgg cgctgtatgt gctggcgttt ctcgaccgtt cgaatattgg
     5701 ttttgccaaa cagacctacc agattgatac cgggctgagt aatgaagctt atgcgctggg
     5761 agcaggcatt ttctttgtgg tatacgcgtt tctgggggtt ccggcgaatc ttttgatgcg
     5821 caaactgggg gccagaacct ggattggtac gacaacactg ctgtggggat ttctttcggc
     5881 tgccatggca tgggccgata ctgaagcgaa atttctgatc gttcgcactc tgcttggtgc
     5941 tgcggaggcc gggtttttcc ctggtatgat ttatctcact tcgcaatggt ttccgcagcg
     6001 taatcgcgcc agcattatgg ggctgttcta tatgggcgca ccgctggcgt taacactggg
     6061 atcaccgctt tccggcgcgc tgctggagat gcatggattt atggggcatc ccggctggtt
     6121 ctggatgttt gtgattgaag gattgctggc agtcggcgct ggggtattca cattcttttg
     6181 gcttgatgac acaccggggc aggcacgttt tctgagtaaa caagaaaaaa cgttgcttat
     6241 caatcaactg gcaagtgaag aacaacagaa agtgacttct cgattgagcg atgcgctgcg
     6301 taatgggcga gtctggcaac tggcgattat ctacctgacc attcaagtgg cggtttacgg
     6361 attaattttc ttcctgccga cccaggttgc tgcattgctg gggacaaaag tgggctttac
     6421 ggcgtcggtg gtcaccgcca ttccgtgggt tgcggccttg tttgggacct ggcttattcc
     6481 gcgctactcc gataaaaccg gcgaacggcg taatgtcgca gcgctgacat tactggcggc
     6541 gggcattggt attggtctct ccgggctgct ttctccagta ctggcgatcg tagcactgtg
     6601 tgttgcagcc atcgggttta ttgccgtgca accggtgttc tggacgatgc cgacacaact
     6661 tctttccggt acggcgctgg ctgcggggat tggttttgta aacctgtttg gtgcagtggg
     6721 cgggtttatt gccccgatcc tgcgcgtgaa agcagaaacg ttattttcca gtgatgcggc
     6781 gggattactg acgctggcag cggtggcggt catcggttcg ctgattattt tcactctgcg
     6841 tgtaaatcgc actgttgcgc agaccgacgt ggcacatcat taaatagttt aaggaacacg
     6901 atgaacgcat tattaaccaa tccctttaaa gaacgtttac gcaagggcga agtgcaaatt
     6961 ggtctgtggt taagctcaac gactgcctat atggcagaaa ttgccgccac ttccggttat
     7021 gactggttgc tgattgacgg ggagcatgcg ccaaacacca ttcaggatct ttatcaccag
     7081 ctacaggcgg tagcgcccta tgccagccaa cccgtgatcc gtccggtgga aggcagtaag
     7141 ccgctgatta aacaagtcct ggatattggc gcgcaaactc tactgatccc gatggtcgat
     7201 actgccgatc aggcacgtca ggtggtgtct gccacgcgct atcctcccta cggtgagcgt
     7261 ggtgttgggg ccagtgtggc acgggctgcg cgatggggac gcattgagaa ttacatggcg
     7321 caagtcaacg attcgctttg tctgttggtg caggtggaaa gtaaaacggc actggataac
     7381 ctggacgaaa tcctcgatgt cgaagggatt gatggcgtgt ttattggacc tgcggatctt
     7441 tctgcgtcgt tgggctaccc ggataacgcc gggcacccgg aagtgcagcg aattattgaa
     7501 accagcattc ggcggatccg tgctgcgggt aaagcggctg gttttctggc tgtggctcct
     7561 gatatggcgc agcaatgcct ggcgtgggga gcgaactttg tcgctgttgg cgttgacacg
     7621 atgctctaca gcgatgccct ggatcaacga ctggcgatgt ttaaatcagg caaaaatggg
     7681 ccacgcgtaa aaggtagtta ttgatatcaa aggcccatgg ggatcggctg tgggcctgtg
     7741 ttaattagtg gttattcgct gccagatcgg cttcgcttag ctgagtggcc gcgagcacct
     7801 gatcacgatc aatgccctgt tccagcatgc gcaaagcaat tttaatggct tgttcatgca
     7861 tgccttcctg caaaccttct aatttacctt cttgccagcc ttcaatctta ccctcctgcc
     7921 agccaatttg atgtccttcc tgccgtagcc gttcagcaat agtcatcaat ctctcctttt
     7981 aatgacagtt cggaatatca gcatcagtga gttgggttgc cgccagcaca atctcacgtt
     8041 caaagccctg ctccagcatg cgcaaggcaa ttttaatggc ttgctcatgc atgccttcct
     8101 gcaaaccttc taatttacct ttctgcaaac cctccaattt accttgctgc aaaccttcta
     8161 atttaccttc ttgccagcct tcaattttac cttcttgcca gccaatttga tgtccttcct
     8221 gccgtagccg ttcagcaata gtcattaatc tctccttttg tagtggtgaa cgttcggcaa
     8281 tctcctgaat aaagcgggtg aaacgggagg tatcgccgca ttgcagcaga taattaaaca
     8341 gtgtttgtag ctggctgtca ttagtgaagt ctctaaccaa aagcgtggtg atcctgtcga
     8401 ccataccgat taaatcgcgg tcgcgaatat gcttttgaat cagttccagc agagctatac
     8461 gccgatgttg catgatctca tcgtcaggta cgatggtgat atccaccaac ggaaaagctt
     8521 cggtgtacaa ctgccgggca agttgcggat cgtcaaactc atccagccag ttgagtgagt
     8581 acgggtaggg cgaggcttcg ccatgataaa acagcaatgg caccaccagc ggaactctgt
     8641 catagccttt atccaggtga cgctgcatgg cggcagtggc atagcgcatt agccgaaaag
     8701 ccatattctt ttctgcagag ctttgatgtt caatcacgca gtagatatag ccgtcaccct
     8761 cgctggtttc cacggaccac aaaacatccg agtagtaagc gcgtaaactt ttttcaataa
     8821 aactggtggg ttccaggcgt aaggtttgca ggttgcaaag cttgcgcagc ggctctggta
     8881 gatgtatttc cagaaaatcc cgtgcggttt cgggtgtgaa cataaaggtt ttaaacaccg
     8941 catcatgcgg ggaggaggtt gttgattcgg tcatggttgt ccgtcacctg atatttatga
     9001 tgacgcgaca ttacggttat cccaggcctt tgatatctgc cagtttcagc ctttgcgaga
     9061 cgttttcaga ggaattttca ctgcgttgca acgcatacat tgggcacgga atcgtgtacg
     9121 caaaaatgcc cggtaacaac atgcttaccg ggcatcagaa aggagtttaa gccaacgcct
     9181 gtgccagcag cgtaatcgga tgttcgcagc gaagacttgt ggacatctca atctgccatt
     9241 tgcaggtttc gcagtcggtg accaccagat ctgcgccgct ctcttctatc tggcggaaca
     9301 gtggtgcgcc gatggcttgt gaagtggggt agttctcttt tttgaaaccg taagttcccg
     9361 caataccgca gcactgggaa tccagcaccg ttaactcaag ccccgggatt ttacgcaaca
     9421 gctccagggt gtagagcgtc cagcccattt tttccatatg gcacggagtg tgataaacca
     9481 ctttcagcgg cagcggtttc agcggtaacg ttttgccttc gtccagcttg cgccacagcc
     9541 agcgggtcgc cagttcgata tgatcgcgca agcctttgtt gtcgacattc agcacttctg
     9601 ggtattcgtc gcgcagggca aatgtacacg ttgaggaggt ggcaatcacc ggaatgcctt
     9661 ttactcccac agcttcgcgg atcgactcta cattcgtaat tgcctgtttg cgtgctttat
     9721 cggtaaaacc gttggcgatc agcggtacgc cgcagcattt ttctttactg agcagttgta
     9781 cgccggtatc catcgcgttg agcactttaa ttaaatcttt gcctagttgc ggatggttgt
     9841 agttaacgaa gcagccgtga aagaaagcga cctggtcttt atactgcgct tgctgagccg
     9901 ccacgctgcg ataccagcga cggaacgtgc cgaaggagta tttcggtagc gtgcggcgat
     9961 gatcgatttt taacgccgca tcaagcagct gacgcaccgg tttcagcgag gtagcggtgt
    10021 tgacgatggg tgcgaacggc gtggatacgc tacccatcag gtcggtatga ctcaacacaa
    10081 aattacgcag cgacgggcgc gtggtgtcat atttcgcccg cgcgcgctgg ataatatcgc
    10141 caatcttcac atcggacggg caggcgactt cacaacgttt gcagttgatg caatatttca
    10201 gcgcctcgtc atacagtgcg ccatctttca aacgcagacg ctcgccatcc ggcccggctt
    10261 gttttggccc cggataaccc ggattcaccc ggctcaccgg gcaggcggtg gtgcagacgg
    10321 tgcacttaat gcagttttcg aagctggtgt cgttcattgt tggcctcctg cgcgttgggc
    10381 aatctgttga gcggcatgta aagcactgac ggcacaaaca ccgccgccgc atccctgggc
    10441 gatgggatca aatccgccca gcaccgaacc gatggcaaac aggttctcaa tggtttgccc
    10501 tgcctgcgac gggcgtagtg cctcatcagt ggttacaccg aactgctgcc acggctgcgg
    10561 cgcaaaaaaa tcgcccttat accattcacc ccgcgtagcg gtttgtagca catcaaggcc
    10621 gagaatcggc tcgcgaatgc cgtcacgttc cgctaccagt ccgccgctaa agaaactgcc
    10681 gctcgcaagc accgcaaatc gtgggcgcag cgggatatcg gcgtgattgc gcgtccagat
    10741 ttcattcact acaccatttt tacaggtcac ttttttcact tcatcgcccg gcatccacac
    10801 gccgccctgg cgcacaaact ggcgctgtaa ctggttttgc agacgaatgc ccagcacgga
    10861 aggcggcagc gttggcaaaa gcatcaatga acaaggtagt ttttcattca accaatgcca
    10921 cagtttgtca tcggccaggc cgaagcaggc gggcatcagg atcatttcgc aggtattggc
    10981 gaccggaata agcgcatcaa gtaacaacgg ccagttttct tcattatcaa ggaagcgggc
    11041 aatattcacc gcccggaact cggtggcgtt attgcgcagc acatccagtt ccggcagttc
    11101 aatttcagcg gtttcaactt taagatccaa ttcgcgcaat gaagccgccg caagatgcgc
    11161 ctgaaaatcc atcaggccgc taattcccac tacacatatt ttcttcgcgg gcagcggcca
    11221 gacagggact tctggcgaac ttagccaggt tgagcgcaga gtgccgagcg gcgtaatccg
    11281 ctggtgagcc agttctacgc tgccctgcaa ttgcgcaccg ctttcagcga ttaatgcctg
    11341 cgcctggcaa gcgagatcga gcacgcgttg aggcccgaga agagtgtaag gatgggcagg
    11401 tgcctgctga cgcaaagatt ccagtccact gtgaatgtct gtcaccggtt gaccatccgg
    11461 cagatggctc agcaaatcca gcgatccaga tgagaaatgg agcgcgcttt gaccacgagt
    11521 gacaatggca cagcgcaggc cgtgtttttg cagttgcagg ccacagagta atccggcgag
    11581 gccgccgccc ataatgacag tatcaaagcg catctttctg ctccttctcc agaccacaca
    11641 atccctgata aacccagcgg gtaaattcgc tttcgcgcag tgcatctccc caggcgatgg
    11701 gttgcacgcc tttccagcgt tcgtttagga aggtggaaag ttgctcaata gattgcgcgg
    11761 acgtcgtgac gttaaaacgt tgcagcagtc cggcagcgcg gcaggcgcag agctcgccct
    11821 ggcaggtgcc catccccaca cgggtacgac ggcgtaaatc cagcaggcta ttaacgttta
    11881 aattttctac cgcgtactgc acttcacccg cagttaccgc ttcgcactca cataccaggc
    11941 tacggtgcag acggccttcg ctcagccagg caggcgtgcg atcgccatga cgataaaccg
    12001 cagaaccgcg cagcggggca ggtagggaga tgactttacg caaggtaact tcagcgggtt
    12061 cctgtgaacc aggaagtgcc agatcggcgg tcgtacaggg gcgcgtgttg cccagtttgc
    12121 ggcatacggc atcggtagcc cattccgcca tcagccgata ggtcatcagt ttgccaccgg
    12181 tgatggtgat aaacccgtcc agaccatcgc gttcagcatg gtcgagcagc acgatgccac
    12241 ggctgacgtt acgtccgctc ggatcgtcat cgctggcaac cagcgggcgt acgccagagt
    12301 aggcccgcaa aatgcgcgtt ttcgccatca cgggggccag tttttcccct tcacgcagca
    12361 gaatatcaac ttcttctgcc gttactcgat tatcgtcaat ctcgttgtaa tcaatacgta
    12421 aagaggtggt gccaatcagc gaaatggtat cgccaggcac cagaatatcg gcgtcggaag
    12481 gtttgcggca gcggttgatc acatgctgat taatgcggtg atccatgatc agcagcgatc
    12541 ctttcgccgg gaacatgcga atgcgcagat cggcatattc ggcaatgtgt tgcccccaga
    12601 tcccggcggc attaactacg acaggtgcat gaagtgcctg aatttcgccg gtgagatggt
    12661 tacgtacacg aacgccgcac accgccgcgc cttcacgaat cagccccgtg acttcatgag
    12721 cggtaaggat aacggcaccg tgttctttgg catccagcat gtttgctgct gtcagacgaa
    12781 atggatcaac ggtgccatcc ggaactttca ccgcgccaat cagtgccggg ttaacggcag
    12841 gttcgataat gcgcgcttgc tgcggatcaa tggcttctgc gctgatccct gcttcttcgc
    12901 aggcgcggat aaaagtggcc tggaaggaga ggtcatcttc cggcagggtg ataaacaggc
    12961 cgttggttgg ttctacgcag tgacgtgcaa tgcgtttcag gatctggttt tcactaatac
    13021 attcgcgggc cgattccgca tcggttaccg catagcgcgc accgctgtgc agcaggccgt
    13081 ggttacgccc ggtggcaccg gttgcgatgt cgtggcgctc aaccaaaatc acgcgcagcc
    13141 cgcgcagggc acagtcgcgg gcaatcccgg ctcccgttgc gccaccgcca atgataatca
    13201 cgtcacttga ttgcgagtcg cgagttttca ttgttatccc tcagaagttc gttttttacc
    13261 atttagccat agtaaaaaca tgaattgttt gatttcgcgc atattcgctc ataattcgaa
    13321 agtgaaacgt gatttcatgc gtcattctga acatttcaac catcgtattt aataatgtgt
    13381 gcggtaattc acatttaatt tatgaatgtt ttcttaacat cgcggcaact caagaaacgg
    13441 caggttctcc cactgaatca ggctgttaat cataaataag accacgggcc acggaggcta
    13501 tcaatgttga gtatttttaa accagcgcca cacaaagcgc gcttacctgc cgcggagatc
    13561 gatccgactt atcgtcgatt gcgctggcaa attttcctgg ggatattctt tggctatgct
    13621 gcttactatt tggttcgtaa gaactttgcg ctcgctatgc cttatctggt tgagcaggga
    13681 ttctcacgcg gtgatttagg ttttgccctt tcggggatct cgattgctta tggattttcg
    13741 aaattcatca tgggttcggt atcggatcgc tcgaatccgc gcgttttcct gcccgcaggt
    13801 ttgattctgg cggcggcagt gatgttgttt atgggctttg tgccatgggc gacgtcgagc
    13861 attgcggtga tgtttgtact gttgttcctc tgcggttggt tccaggggat ggggtggccg
    13921 ccgtgtggtc gtactatggt gcactggtgg tcgcagaaag aacgtggcgg tattgtgtca
    13981 gtgtggaact gtgcgcacaa cgtcggtggt ggtattccgc cgctgctgtt cctgctgggg
    14041 atggcctggt tcaatgactg gcacgcggcg ctctatatgc ccgctttctg cgccattctg
    14101 gtggcactgt tcgcctttgc gatgatgcgc gataccccgc aatcctgtgg cctgccgccg
    14161 attgaagagt acaaaaatga ttatccggac gactataacg aaaaagcgga acaggagctg
    14221 accgcgaagc agatcttcat gcagtacgtg ctgccgaaca aactgctgtg gtatatcgcc
    14281 atcgccaacg tgttcgttta tctgctgcgt tacggcatcc tcgactggtc accgacttat
    14341 ctgaaagagg ttaagcattt cgcgctggat aaatcctcct gggcctactt tctttatgaa
    14401 tatgcaggta ttccgggcac cctgctgtgc ggctggatgt cggataaagt ctttcgtggt
    14461 aaccgtgggg caaccggcgt cttctttatg acactggtga ccatcgcgac tatcgtttac
    14521 tggatgaacc cggcaggtaa cccaaccgtc gatatgattt gtatgattgt tatcggcttc
    14581 ctgatctatg gccctgtgat gctgatcggt ctacatgcgc tggaactggc accgaaaaaa
    14641 gcggcaggta cggcagcggg ttttaccggg ctgtttggtt acctgggcgg ttcggtggcg
    14701 gcgagcgcga ttgttggcta caccgtggac ttcttcggct gggatggcgg ctttatggta
    14761 atgattggcg gcagcattct ggcggttatc ttgttgattg ttgtgatgat tggcgaaaaa
    14821 cgtcgccatg aacaattact gcaaaaacgc aacggaggct aatggcatga aattgacgct
    14881 gaaaaacctt agcatggcga tcatgatgag cactatagtc atgggaagca gtgcaatggc
    14941 ggcggacagc aacgaaaaaa tagtcatcgc ccatcgcggt gccagtggat atttgccgga
    15001 gcatacgctg ccagcaaaag cgatggcgta tgcgcaggga gcggattatc tggaacagga
    15061 tttggtgatg accaaagacg accatctggt tgttctgcat gaccattatc tcgatcgtgt
    15121 tactgatgtt gccgatcgtt tcccggatcg ggcgcgcaaa gacggtcgtt actacgcgat
    15181 agatttcacg ctggatgaaa ttaagtcgct gaaatttacc gaaggtttcg atattgaaaa
    15241 cggtaaaaaa gtgcagactt atccggggcg tttcccaatg ggtaaatctg acttccgggt
    15301 gcacaccttt gaagaagaga ttgaatttgt tcaggggtta aaccactcta ccgggaaaaa
    15361 tatcggtatc tatccagaaa ttaaagcgcc gtggttccat catcaggaag ggaaggatat
    15421 tgcggcaaaa acgctggaag tgctgaagaa atatggttac accggtaagg acgacaaagt
    15481 ttatttgcaa tgttttgatg ctgatgagct gaagcgtatt aagaatgagc tggaacctaa
    15541 aatgggtatg gatctcaatc tggtacagct gattgcctat accgactgga atgaaacgca
    15601 gcagaaacag ccggacggaa gctgggttaa ttacaattac gactggatgt ttaagccggg
    15661 tgccatgaaa caggtggcgg aatatgctga tggtattggt ccggattacc atatgttgat
    15721 tgaggagaca tcgcagccgg gtaatatcaa actcactggc atggtgcaag atgctcagca
    15781 gaataaactg gtagtgcatc cttataccgt gcggtcagat aaactgcctg aatacactac
    15841 tgatgtgaat cagttatatg atgttctgta taacaaagcg ggtgtaaatg ggctatttac
    15901 tgacttccct gataaggcag taaaattcct taataaagag taaattaact accggatggc
    15961 acttatgtgc tatccgatac cactcttcat taaagtctgt gggttatcct taattgcaat
    16021 tatttagagc gagatgactt gttcccggca taagatactc gtcaatacaa cacgtattat
    16081 taagattttc ctcagctaaa catctatagt cattgtcgtt aataaaaaac gacaggcgat
    16141 agggtatggc agtttcagca aaacacgacg aatttaatca ctggtgggca acagagggcg
    16201 actgggttga agagcctaac tatcgccgta atggtatgag cggggtgcaa tgcgtcgagc
    16261 gcaacggcaa aaagctgtat gtaaagcgca tgacgcatca tctgtttcat tccgtacgtt
    16321 atccgttcgg ccgaccaacg attgtccgtg aggttgcggt aattaaagaa ctggaacggg
    16381 ccggtgtcat cgtgccgaag attgtttttg gtgaagcggt gaaaattgag ggtgaatggc
    16441 gcgcgttgct ggtgactgaa gatatggcgg ggttcatcag cattgctgac tggtatgccc
    16501 ggcatgcagt atcgccttat tctgacgaag tacggcaagc catgttgaaa gcagtggcgc
    16561 tggcgtttaa gaaaatgcat agcgttaatc gtcagcatgg ctgttgttat gttcgccata
    16621 tctatgtgaa aacagaaggt aaggcagaag ctggatttct tgacctggag aaaagtcgtc
    16681 gccgcttgcg tcgtgataaa gcgattaatc atgacttccg ccagctggaa aaatatctgg
    16741 agccgatccc caaagcggac tgggagcagg tgaaagcata ttactacgct atgtaatcgt
    16801 tgtaggccag ataagacgta taagcgtcgt atctggcgtt aaaaccaatt cacatctcga
    16861 tttcaatatc gccttttgcc cggcaacaac agggcaaaat ttcccccggc tgaataaaag
    16921 ctaacggttc ggcaatccag tccacctggc ctgcgaccag tcgggtgcga caggagccgc
    16981 agtaaccttc gcggcactgg tactcaaccg ccacattgtg ggattccagc gccgccagaa
    17041 gggaagggtg ttcatcctgg cacagcagtt gtgtgccagt aatgcgcagg gtaacgcggg
    17101 ccatcagagc tggaagttac tcaaatcgtc ggtgtccact tccgcgtcaa tctgcccgac
    17161 cagataagaa ctgacttcca cttcctgcgg agcaacctgc acgttatcag acaccagcca
    17221 ggtgttgatc cacgggatcg ggttggagcg cgtctggaac ggcagatcca aaccgactgc
    17281 ctgcatacgg atattggtga tgtattcaac gtactggcag agaatgtctt tattcagacc
    17341 aatcatcgaa ccatcacgga acagataatc cgcccagtct ttctcttgct gtgccgcctg
    17401 gacaaacagg tcatagcact cctgcttaca ttcttcggca atttccgcca tctccggatc
    17461 atccgcgccg ctgcgcagca gattcagcat atgctgggtg ccggtcaggt gcagggcttc
    17521 gtcgcgggca atcaggcgaa taattttggc gttaccttcc atcagctcac gttcagcgaa
    17581 tgcgaaagag caggcaaagc tgacgtagaa gcggatcgct tccagcgcgt taacgctcat
    17641 caggcagaga tacagttttt tcttcagctc gcgcaggcta acggttacgg ttttaccgtt
    17701 aacggtgtgg gtgccttcgc ccagcagatg ccagtagctg gtcatttcga tcagttcatc
    17761 gtaatagctg gagatcccct ccgcacgttt ctggatctgc tcgttggtaa cgatatcgtc
    17821 aaagacaaca gacggatcgt taacgatatt acggatgata tgggtatagg agcgggaatg
    17881 aatcgtttct gagaacgccc aggtttctac ccaggtttcc agttccggga tcgagatcag
    17941 cggcagcagt gccacgttcg gactgcgacc ctgaatggaa tccagcagcg tctgatattt
    18001 caggttgctg ataaagatgt gtttttcgtg ttcaggcagt gcctggtaat cgatacggtc
    18061 gcgggagacg tcaacttctt ccggacgcca gaagaaagag agctgctttt cgatcagctt
    18121 ttcgaagatg tcatattttt gctgatcgta gcgagccacg ttgaccggct gaccaaagaa
    18181 cattggttct ttgagctgat catttttcgt ctgtgaaaag gtggtatatg ccatgaatgt
    18241 gtcctgtggt tttattaccc ctcacccgtc ccctctcccg caaggggaga ggggacggtt
    18301 tggtgcaaag actgggggat tatcagatct tacatgcgcc gctttcgcag ccatcgtcct
    18361 ggattgacgg caccagatcg tcctgcgcgt cttctgcgcc gtcacgggtg ttctgataat
    18421 acagcgtttt gaccccgaat ttgtaggcag tgagcaggtc tttcagcaac tgctgcatcg
    18481 gcacttttcc tgacgggaaa cgtgacggat cgtagttggt gttagcagag atcgactgat
    18541 cgataaattt ctgcatgata cccaccagtt gcaggtagcc atcgttaccc ggcatttccc
    18601 acaacagctc ataggcgtcg tgcagatgct cgtagtccgg caccacctgg cgcagaatac
    18661 cgtctttcga cgctttgatg ctgacgtaac cgcgcggcgg ttcaataccg ttagtggcgt
    18721 tagagatctg cgaagaagtc tcggacggca tcagggcaga aagcgtggag ttacgcaggc
    18781 cgtgcgtttt gattgactca cgcagtgctt cccagtcgta atgcagcggc tcattagcga
    18841 tggcatccag atctttctta taggtatcga tcggcaggat ccctttcgcg tatgtggttt
    18901 cgttaaacca cgggcacgcg ccttgctctt tcgccagctc attagacgct ttcagcaggt
    18961 aatactgaat ggcttcgaag gttttatgcg tcaggttgtt ggcgctgccg tcggagtagc
    19021 gtttaccgtg cttcgccagg tagtaagcga agttgatcac accaataccc agcgtacgac
    19081 gacccatcgc tccacgtttg gcggccggga tcgggtaatc ctgataatcc agcagcgcgt
    19141 cgagtgcgcg tactgccaga attgccagct cttccagttc atccaggctg ttaattgcgc
    19201 ccaggttgaa agcagacagc gtacacagtg cgatttcacc gttctcgtcg ttgacgtcgt
    19261 tcagcggttt ggtcggcagg gcgatttcca ggcacaggtt agactggcgc actggcgcga
    19321 tggccggatc aaacgggcta tgggtattgc agtggtcaac gttctgaata tagatacgac
    19381 cggtagacgc acgttcctgc atcatcagcg agaacagctc aacggctttc acacgctgct
    19441 tgcggatgct gtcgtctttc tcatatttgg tatacagacg ttcaaactct tcctgatcgg
    19501 cgaagaacgc gtcgtacagc cccggtacgt cggacgggct gaacagagtg atatcttcac
    19561 ctttcagcag acgggtatac atcagtttgt tgatttgaac cccgtagtcc atatgacgca
    19621 cgcggttgcc ttccacacca cggttgtttt tcaacaccag caggctttcc acttccagat
    19681 gccacatcgg gtagaacagc gttgccgcac cgccgcgcac accgccctga gagcaggatt
    19741 tcaccgctgt ctggaaatgt ttgtagaacg gaatacaacc ggtatggaac gcttcgccac
    19801 cgcgaatcgg gctacccagc gcacgaatac gcccggcgtt gatgccgatc ccggcacgct
    19861 gggaaacgta tttaacaatc gcgctggagg tggcgttaat ggaatccagg ctgtcgccgc
    19921 actcgatcag cacgcatgag ctgaactgac gagtcggggt acgcacgccg gacatgattg
    19981 gcgtcggcag cgaaatttta aatgtggaaa ccgcgtcgta aaaacgcttc acgtattgca
    20041 ggcgcgtttc acgcgggtag ttcgagaaca ggcacgcggc aaccagaata taaaggaact
    20101 gggcgctttc gtagatttcg ccggtcacgc ggttctgtac cagatatttg ccttccagct
    20161 gcttaacggc agcataagag aaggtcatat cacggtcgtg atcgataaac gtgtccatct
    20221 gcttgaactc ttcttccgtg tagtcttcca gcagatgatt atcgtatttg cccatctcga
    20281 ccattttcac cacatggtcg tacagcgcag gcggctcaaa ctgaccgtag gcttttttac
    20341 gcaggtggaa gatcgccaga cgtgcggcga gatactgata atccggcgca tcacgggaga
    20401 tcaggtctgc ggcagccttg ataatggttt cgtggatgtc agaggtcttg ataccgtcat
    20461 aaaactgaat gtgggagcgc agctcgacct gggaaatcga aacgttatgc agtccttctg
    20521 ccgcccaatc cagaacgcga tggattttgt cgagattgat gcgctctgtg ctaccgtcgc
    20581 gctttgtcac cagcagattc tgattcatgt atgtcgtacc tgtttttcaa tagcttcatg
    20641 cagactacct gtagtgaggg aagctgctaa gaacactata tatagggggt atgtttggga
    20701 ttcactgcaa gatagtgtga aactggccct cttgcaagtg cataactttg tggataactc
    20761 aggaaggaaa aagtggcttc cgcgcacctt aggtcagaca aggtgtccgg gaaagtcaat
    20821 gggaagagaa aaatttgtta aaaataaccg ttcggtgaat tcttgaacgg taaaatagga
    20881 taggtaaatt gatatagatg gtttattaat cttgttgcta atgattgcca aaattgatct
    20941 aggcacaagt cgtcacataa tctgatgtat ctgttgtggt caatatataa gcgaatgtaa
    21001 gcgattgttg agtcggaaat ggttgtttta tattcggtta ttgttaaata ctaagccaat
    21061 ttgttacttt tgcatatatt ataagaatat tatttattgc tttaattcag tttaaatata
    21121 accgacttac cttaaagtta ttaat
//
LOCUS       DAPOXO010000088        20491 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPOXO010000088 DAPOXO010000000
VERSION     DAPOXO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20491
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.088"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            192..344
                     /gene="hokA"
                     /locus_tag="ROH59_003950"
     CDS             192..344
                     /gene="hokA"
                     /locus_tag="ROH59_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HDX4806376.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQENYELAAFL
                     ACKLKE"
     gene            complement(532..744)
                     /gene="cspA"
                     /locus_tag="ROH59_003951"
     CDS             complement(532..744)
                     /gene="cspA"
                     /locus_tag="ROH59_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HDX4806377.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(1025..1315)
                     /locus_tag="ROH59_003952"
     CDS             complement(1025..1315)
                     /locus_tag="ROH59_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HDX4806378.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            1749..2459
                     /locus_tag="ROH59_003953"
     CDS             1749..2459
                     /locus_tag="ROH59_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HDX4806379.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(2509..3483)
                     /gene="ghrB"
                     /locus_tag="ROH59_003954"
     CDS             complement(2509..3483)
                     /gene="ghrB"
                     /locus_tag="ROH59_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HDX4806380.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVALPHIGSATHETRYGMAACAVDNLINALQGKVEKNCVNPHVVD"
     gene            complement(3587..4246)
                     /locus_tag="ROH59_003955"
     CDS             complement(3587..4246)
                     /locus_tag="ROH59_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HDX4806381.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGSHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            4399..6732
                     /gene="bisC"
                     /locus_tag="ROH59_003956"
     CDS             4399..6732
                     /gene="bisC"
                     /locus_tag="ROH59_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin sulfoxide reductase"
                     /protein_id="HDX4806382.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSRGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALELIHHQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLARCTTGYA
                     VFASYLLGESDGIAKNAEWAAEICGVGAAKIRELAAIFHQNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRAAVLSSMQGSLPGGTDAVDK
                     IPVARIVEALENPGGAYQHNGMDRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRDEARNDF
                     DVFAELSERWEKGGYARFTEGKSELQWLETFYNVARQRGASQQVELPPFAEFWQANQL
                     IEMPENPDSERFIRFADFRRDPQAHPLKTASGKIEIFSQRIADYAYPDCPGHPMWLAP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQTRGIQD
                     GDTVRLWNSRGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTVTAFEPPASS"
     gene            complement(6701..7141)
                     /locus_tag="ROH59_003957"
     CDS             complement(6701..7141)
                     /locus_tag="ROH59_003957"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX4806383.1"
                     /translation="MIREAQRSELPALLELWLESTTWGHPFIKSSYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRHPHLML
                     EVYQKNQPAIDFYHAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(7138..7701)
                     /gene="tag"
                     /locus_tag="ROH59_003958"
     CDS             complement(7138..7701)
                     /gene="tag"
                     /locus_tag="ROH59_003958"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDX4806384.1"
                     /translation="MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFADFVWSFVNHQPQVTQATTLSEIPTSTPASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCHPGNKP"
     gene            7859..8557
                     /locus_tag="ROH59_003959"
     CDS             7859..8557
                     /locus_tag="ROH59_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312460.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX4806385.1"
                     /translation="MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGHS
                     TERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYEQ
                     VTTGPVAALHYDGTTTSMYNEFGDSTTTLADPLWHASVSTLGWRVDSRLGDLRPWAQI
                     SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALSQAENTTN
                     NSDYLYTMGVSARF"
     gene            8786..9994
                     /locus_tag="ROH59_003960"
     CDS             8786..9994
                     /locus_tag="ROH59_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806386.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLGAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSNNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTHLLE
                     TVGLEKTFVIWGAIVLVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDAISAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVIALVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KMLREAHGSL"
     gene            10318..12009
                     /gene="eptB"
                     /locus_tag="ROH59_003961"
     CDS             10318..12009
                     /gene="eptB"
                     /locus_tag="ROH59_003961"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HDX4806387.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPVNAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAREAAAN"
     gene            12101..12177
                     /locus_tag="ROH59_003962"
     tRNA            12101..12177
                     /locus_tag="ROH59_003962"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12135..12137,aa:Pro,seq:cgg)
     gene            12921..14528
                     /gene="dppA"
                     /locus_tag="ROH59_003963"
     CDS             12921..14528
                     /gene="dppA"
                     /locus_tag="ROH59_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HDX4806388.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPKIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
     gene            14835..15854
                     /gene="dppB"
                     /locus_tag="ROH59_003964"
     CDS             14835..15854
                     /gene="dppB"
                     /locus_tag="ROH59_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HDX4806389.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            15864..16766
                     /gene="dppC"
                     /locus_tag="ROH59_003965"
     CDS             15864..16766
                     /gene="dppC"
                     /locus_tag="ROH59_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HDX4806390.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            16777..17760
                     /gene="dppD"
                     /locus_tag="ROH59_003966"
     CDS             16777..17760
                     /gene="dppD"
                     /locus_tag="ROH59_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDX4806391.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDKCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            17757..18761
                     /gene="dppF"
                     /locus_tag="ROH59_003967"
     CDS             17757..18761
                     /gene="dppF"
                     /locus_tag="ROH59_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HDX4806392.1"
                     /translation="MSTHEATPQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIETPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLTGELPSPLNPPPGCAFNARCRRRFGPCIQLQPQLKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(18791..20062)
                     /locus_tag="ROH59_003968"
     CDS             complement(18791..20062)
                     /locus_tag="ROH59_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HDX4806393.1"
                     /translation="MQHNTLPKHDQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLFYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASDFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYVTLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTRKINSRVLTLAICTFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     SQLEKLRGFKAWMILLYGILLCLSPLLKLIE"
BASE COUNT         4923 a         5034 c         5378 g         5156 t
ORIGIN      
        1 atatcaagga gaagaaacga acttattaag ctggaatagc cacgggtgct tgaggctgtt
       61 tgtctcaggt attcaccgaa aggcagacag agaaaagccc cacctgacta taaatcaaag
      121 tgaggctacc ctatgcctga acaccataag gttagcctct tactcgttgg aaatcaacac
      181 aggaggctgg gatgccgcag aaatatagat tactttcttt aatagtgatt tgtttcacgc
      241 ttttattttt cacctggatg ataagagatt cactgtgtga attgcatatt aaacaggaga
      301 attatgagct ggccgcgttt ttagcctgca aattgaaaga gtaagaatct tcggcgggaa
      361 gttattcccg cctttcttac ggcgttacgc attctcatta cacccaaatt tattcttcac
      421 aaaaataata atagatttta ttacgtgacc gattatttat ttcctgaaaa acaaataaaa
      481 aaatccccgc caaatggcag ggatcttaga ttctgtgctt ttaagcagag attacaggct
      541 ggttacgtta ccagctgccg ggcctttagc gccgctttcg atggtgaagg acactttctg
      601 accttcgtcc agagatttgt aaccatcgtt ctggatagca gagaagtgta cgaacacgtc
      661 tttagagcca tcgtcaggag tgatgaagcc gaagcctttg tcagcgttga accattttac
      721 gataccagtc attttaccgg acatagtgta ttacctttaa taattaattg tgcctttcgg
      781 cgatatggcg tgctttacag attttgaagc gttaaaggaa tgtgcactac gaggggtatc
      841 aacgataact cttgaaggga cttgccttac tacactgctt taatggtctg tacgtcaaac
      901 cgttgatgtg cattaagcca cgcattggtg ggtgatgcaa caattatttt tcatatttat
      961 gattaatcgg ttggaaaacg gtcctgttat caggaccgta aacagaaata aagtggataa
     1021 aagcctattc catcaactgc ttacttaatg ccgggttggc ttgaatcaaa cgcatcaatt
     1081 ttagttcggc acttgaaggc ttcacgcgtc tggattccca ttcctttacc atggcgactg
     1141 atacgcccaa aacccgggcg aaatcatcga tttttaatcc tgtccctttt cgtaactgct
     1201 caatttcggt acaggacgtt gttctgtgcg tcagggtaat tttctgcgtt tcatctttaa
     1261 aaacaatctg ttccaggctg ctcaacagct catgcattgg atctttatat tccattgaaa
     1321 actcctcaaa tcacactgcg ggatcgtgaa ttgcatcgaa gctcattaag aatagtcggg
     1381 aaaaacagac acagcggggt gtagtcaggg catactctga ctatgattcg attcagccag
     1441 tcatttagcg tgacttatag ccacctaacg atctgataaa tgccgatata tctcttacca
     1501 ctcccggttt gtaaagattt cgaaaatcta acgttctgcg aaggcgtaaa tctctggcta
     1561 caaaaaaggc aacggcaata tcatttttta acaatgaaac aacaaattaa ccttgtttca
     1621 ttttctccat gattttacca ggaagattat gtagaaaggg tatcctgcaa gcctgtcctg
     1681 gactatcctt gtcacgtcag acacgcgtgt gtcgttgtgc gctttttttg ggtgaaagga
     1741 gtaagaaaat ggcgacagga aagtcctgct ctcgctggtt tgcgcctctt gcggcgttat
     1801 taatggtagt tagcctgagt gggtgttttg ataaagaagg cgatcagcgt aaagcgttta
     1861 tcgacttcct gcagaataca gtgatgcgta gcggtgaacg tctaccaacc ctgactgccg
     1921 atcagaaaaa acagtttggt ccttttgtct ctgattacgc gattctgtat ggttattctc
     1981 agcaggtgaa tcaggcgatg gattccggtc tgcgcccggt tgtagacagc gttaacgcaa
     2041 ttcgcgtacc gcaggattac gttacgcaaa gcggtccgct gcgtgaaatg aacggttcgc
     2101 tgggtgtgct ggcgcaacag ctgcaaaatg cgaagttgca ggccgatgct gcgcactctg
     2161 cgttaaaaca gagtgatgac ctgaaaccgg tctttgatca ggcattcacc aaagtggtaa
     2221 cgacgccagc tgatgcattg caaccgttga ttccggcggc acaaactttc acgcaacaac
     2281 tggtgatggt tggagactac attgctcagc aaggtactca ggtgagcttt gtcgcaaatg
     2341 gcatccagtt cccgacttca cagcaggcaa gtgaatataa caaactgatt gcgccattac
     2401 cggcacaaca tcaggcgttt aatcaggcct ggactacagc agttactgca acccaataaa
     2461 gagtaaaagc ccgagcgatt atcgggcttt actcctcgca gtcgcggctt agtccacgac
     2521 gtgcggattc acacagttct tctcaacctt tccttgtaac gcattaatca aattatccac
     2581 ggcacaggcg gccatgccat aacgcgtctc atgggtggca gatccaatat gcggtaatgc
     2641 gacgacgttg gccattgaga gcaacggcga atctacggac agtggctctt gttcgaagac
     2701 atccagcccg gcggcgtgaa tttccccttt ctgcaatgca gcaatcagtg cattttcatc
     2761 aaccaccggg ccacgtccgg cattaatgaa aatggcggag gatttcattt tggcgaattg
     2821 ttctgcgcca aacagatgat gcgtctcatc cgttaacggc aggatcaggc aaacgaaatc
     2881 tgactcttgt aacagagtat ccaaatcgca gtagcgggcg ttgaagcgtt cttctgcttc
     2941 tttatggtgg cgacgcgcgt tatagaggat gggcatgttg aagccaaagt gcgcacgttg
     3001 tgccagcgcc atgccgatcc gtcccatccc gacaatgccc agtgttttat ggtgaacgtc
     3061 agtgccgtac cagtccgggc ctatactcgc ggtccattcg cctgctttta cccgttctgc
     3121 tacctccaca acccgacgag cggtagacaa caccagcgcc atcagcgtat cggcgacggt
     3181 ttctgttaat acggttggtg tgtgcatcag cagaattttt cgggcggtaa gcgcatcgac
     3241 atcaaaattg tcatagccga cggagatcgt tgatgtggca cgcagtttcg gcattttttc
     3301 cagcaatgcg gcatcaacat tctcatttga acccagcaag ccttcagctt cggcaaaaat
     3361 tgctgcattt tgttcgacgg tttgtgggct gaggtttgct acctggtgaa cggtgaaatg
     3421 ttcttgcagg cgttgcagta aatcatcagg taaggctttg tagaggataa cggacggctt
     3481 catgcttctc tccattcact gataaggcga tcaccttagc ctgaaatatg atgaaggaaa
     3541 actgaagaat gccaggtgat ttctgcatca cctgacatga aagggattac agtgggctta
     3601 aggtaatttc tacacggcgg ttttgcgcct taccttctgc ggtgctgttg ctggcgattg
     3661 ggttagccgg gccaaggccc tgagtacgga tgcggctggc gtccacgccc tgggtgatca
     3721 acgcgctggc aacggaatcc gcacgctgct gggagagacg catgttcagg tcgtgactcc
     3781 ccgtgctgtc ggtataacca atcacgttaa ccgccgtttt cggatactct ttcagtacca
     3841 ttgccacgcc ggtcagggtg ttagcgcccg ccggtttcag ggttgcgctg ctgctgtcga
     3901 aggtcacatt gttcggcata ttgaggataa tgttatcccc gctgcgggtt acgctaacac
     3961 cagtgccgcg cattttgtca cgcagcttcg cttcctgcac atccatgtaa taaccaacgc
     4021 cgccgcccag agctgcgcct gctgctgcgc caatgagcgc gcctttaccg cgatctttct
     4081 tcgaagaaga gagcgcacca atacccgcgc caacgagaga gcccagacct gcgccgatag
     4141 cagatttacc tgcttcgcgt tcgccggtgt aagggttagt tgtacagcca gataccgcca
     4201 gagcgccact cactacggcg gcaataagat aaacacgttt cttcattgtt aatccttaat
     4261 aaccttttta ttctttgcca cgggttccgt ggcgggagat tatgccgcgt gagcatgaag
     4321 attattcctg ggaatactcg gaaatttgta agtaatattt aactgctcaa tacatctaac
     4381 ctttcaggag tcttcggttt ggccaactca tcctcacgat attccgttct gactgccgcc
     4441 cactgggggc ctatgctggt tgaaaccgac ggcgaaaccg tgtttagctc gcgtggcgcg
     4501 ttagccacag gaatggaaaa ctccttgcag agcgcggttc gcgaccaggt tcacagcaat
     4561 acgcgggtgc gatttccaat ggtgcgcaaa ggctttcttg cgtcaccgga aaatccgcaa
     4621 ggcattcgtg ggcaggatga atttgttcgc gtgagttggg atgaggcgct ggagcttatt
     4681 caccatcaac ataaacgcat tcgtgaggct tatggtccgg catcgatttt tgctggttcc
     4741 tacggctggc gttcaaacgg cgtgctgcat aaggcctcga cattattaca acgctatatg
     4801 gcgttggcag gcggttatac tgggcatctg ggggattatt cgaccggcgc ggcacaggcg
     4861 atcatgccgt atgtcgtggg tggcagcgaa gtttatcaac agcaaaccag ttggccgctg
     4921 gtgctggaac atagcgatgt cgtggtgctg tggagtgcta acccactcaa tacgctgaaa
     4981 attgcgtgga atgcatccga tgagcagggg ctttcttact tttccgcact gcgtgacagc
     5041 gggaaaaagc tgatctgcat tgatccaatg cgatcggaaa ccgtcgattt ctttggcgat
     5101 aaaatggagt gggtggcacc gcacatgggc accgatgttg cgttgatgct ggggatcgcc
     5161 catacgctgg tggaaaatgg ttggcacgac gaagcgtttc tggcgcgttg caccacaggt
     5221 tatgctgtct tcgcctctta tttgctgggc gagagtgacg gaatagcgaa aaacgccgaa
     5281 tgggcggcag agatttgtgg tgttggcgca gcgaaaatcc gcgagctggc ggctattttc
     5341 caccaaaata caaccatgct gatggcaggc tggggaatgc agcgccaaca gtttggtgag
     5401 caaaaacact ggatgatcgt cacgctggcg gcaatgttgg ggcaaatcgg cacacccggc
     5461 ggcggttttg gtctttctta ccattttgcc aatggtggta accccacgcg ccgcgctgcg
     5521 gtgctctctt ccatgcaggg cagcttgccg ggtggcaccg atgcggtaga taaaatccct
     5581 gtcgcccgca ttgttgaagc actggaaaac cctggtggcg catatcaaca taacggtatg
     5641 gaccgacatt tcccggatat tcgttttatc tggtgggcgg gtggtgccaa ctttactcat
     5701 catcaggata ccaatcgcct gatccgtgcc tggcaaaaac cggagctggt ggtgatctcc
     5761 gaatgcttct ggacggctgc ggcgaaacac gcggatatcg ttctgcctgc gaccacctct
     5821 tttgagcgta atgatctcac catgaccggt gattacagta atcagcatct ggtgccgatg
     5881 aagcaagtgg tgccgccacg cgatgaagcg cgtaatgatt ttgatgtttt tgccgagttg
     5941 agtgaacgtt gggagaaggg cggttatgca cgttttacgg aaggaaaaag tgagctgcaa
     6001 tggctggaaa cgttttataa cgttgcccgg cagcgcgggg caagccagca ggttgaattg
     6061 ccgccatttg ctgagttctg gcaagccaac cagttaattg agatgccgga aaacccggac
     6121 agtgagcggt ttattcgctt cgccgatttt cgccgcgatc cgcaggcgca tccattaaaa
     6181 accgccagcg gtaagattga aatcttctcg cagcgtattg ccgattacgc ttatccggat
     6241 tgcccggggc atccaatgtg gctggcgccg gacgaatggc agggtaatgc cgaaccggaa
     6301 cagttgcagg tactttctgc tcatccggcg catcgtctgc acagccagct gaattacagt
     6361 tctctgcgcg aattgtacgc ggtggcaaat cgtgagcctg tcaccattca tcctgacgat
     6421 gcccagacgc gcggcataca agatggcgat actgttcggc tgtggaactc acgcgggcaa
     6481 attcttgccg gcgcggtcat tagcgaggga attaaacctg gcgtgatttg tattcacgaa
     6541 ggcgcatggc cggatttgga tttaaccgct gacggcattt gtaaaaacgg cgcagtgaac
     6601 gtgctgacca aagatctccc cagctcgcgg ctggggaatg gctgtgcggg taatacggcg
     6661 ctggcatggc tggaaaaata caacggtccg gaactgacag ttacagcgtt tgaaccaccg
     6721 gccagctcat aatccaggtg ggtagttggg tttcatcctg ccatgcgcaa tcgacaatgt
     6781 gaaaaccctg cgcatggtag aaatctatcg ccggttgatt tttttgataa acctccagca
     6841 tcagatgggg atggcgctgc tgcacatact gcatcagcgc cttaccaata ccgcgcctga
     6901 cggccttcgg tgcgacaaac attgctgcca gaaatcggcc ttccataatg ctgacaaaac
     6961 cgagaagctt accgtcttct tcccagaccc agttttgcgc gttggcaaga tacgcatccc
     7021 gcaccagcgg aatgcagtca cgccagtaac tcgattttat aaagggatgc ccccaggttg
     7081 tactttccag ccacagttcg aggagcgcgg ggagttctga acgttgcgct tcccgaatca
     7141 tggtttattt cccggatggc aacagcagcc aaccacatga tcattcacca gcccacatgc
     7201 ctgcataaag gagtaacaga ttgtggtacc gacaaactta aaaccacgtt tttttagtgc
     7261 cttagatagg gcgtcggagg cgggtgtaga tgtggggatt tcgctcaacg ttgtggcttg
     7321 tgtcacctgt ggttgatgat tgacaaacga ccagacaaag tcggcaaacg gttcgccgtt
     7381 ctgttccatt tgcaggtacg cccgcgcatt accaataatt gcctgaattt tcccacgatg
     7441 gcggataatc ccggcgtcct gtaccagtct ttcgacatcc tcttcctgca ttgcggcaac
     7501 tttcaccgga tcgaactgat gaaagcatgc gcgatagttt tcgcgttttt tgaggacggt
     7561 gatccacgat aacccagcct gctgcccttc caggcagatc atttcgaaca gttttttact
     7621 gtcagtttca ggcacgcccc attcattatc atggtaggca atataaagcg ggtcctgact
     7681 cacccagccg caacgttcca tactttccct cgctatgtac ccgatcgtaa aaatttcagc
     7741 cgcttttctt gacgcatcgg tgaaaaagtc aatatttaat acagggctac tatgcccgat
     7801 atccttcata caatgacaat aatattgccg aattcggctc ttccctggag tcgtgttaat
     7861 gatcataaaa aaaagcggtg gtcgctggca gctaagcctg cttgcgagcg tggtaatcag
     7921 tgcctttttt ctcaacacag cttacgcctg gcaacaagaa tatatcgttg atacgcaacc
     7981 cggacattcc acagagcgtt acacctggga tagcgatcat caacctgatt acaacgatat
     8041 tttgtcgcaa cgtattcaaa gtagccaaag ggcgctggga ctggaagtca atctggcgga
     8101 agaaacccct gtggatgtga ccagcagtat gagtatgggc tggaattttc ctttatatga
     8161 gcaggttaca accggcccgg tcgcggcatt acattacgat ggcacaacca cctcgatgta
     8221 taacgagttt ggcgacagta ctaccacgct ggccgatccg ttatggcatg ccagcgtgag
     8281 taccttaggc tggcgtgttg actcccggct tggcgatctc cgaccctggg cgcaaatcag
     8341 ctataaccag caatttggcg agaatatctg gaaggcgcaa tcaggcctga gccggatgac
     8401 ggcgacaaac cagaacggca actggctgga tgtcaccgta ggcgctgata tgttgctcaa
     8461 tcaaaatatt gctgcctatg ctgcgctatc tcaggcagaa aataccacta acaatagcga
     8521 ctatctgtat acgatggggg ttagtgccag attttaacgt tatagataca attgaaaccc
     8581 ataaataaca actaatgtgg cgatagtggg gactaactta ctaaataata aatttggcga
     8641 ataattgtcg agtcattcat tcctgaacta atgcatttca ttccgttctg atggcatttc
     8701 atgccgtttt tccccaggca taaagcgcac ttcgttatgg ttgtcagcag agatttttcc
     8761 tttttattac tgcaggaata ctgccatgac accttcaaat tatcagcgta ctcgctggct
     8821 gacactcatc ggtactatca ttacccagtt tgctctgggg tcggtttata cctggagtct
     8881 gtttaacggt gcgctttctg ccaagctggg ggctcctgta agccaggttg ctttctcttt
     8941 cggcttgtta agtctggggc tggcaatttc gtcttctgtt gcgggcaaat tgcaggaacg
     9001 ttttggtgtt aaacgcgtca ctatggcttc cggcattttg ctgggattag gtttcttcct
     9061 gacagcacat tccaacaacc tgatgatgct gtggttaagc gccggtgtgt tggttggtct
     9121 ggcggatggt gcgggttacc tgttgacgct ctctaactgc gtgaagtggt ttccggagcg
     9181 taagggactt atctctgctt ttgctatcgg ttcttatggt ctgggcagcc tgggttttaa
     9241 atttatcgac acgcacctgc tcgaaacggt gggtctggaa aaaacctttg ttatttgggg
     9301 cgcgattgta ctggtgatga ttgtctttgg cgcaacgtta atgaaagatg cgccgaagca
     9361 ggaagtgaaa accagcaatg gtgtggtgga gaaggactac accctggcag agtcgatgcg
     9421 taaaccgcag tactggatgt tagcggttat gttcctgact gcgtgcatga gtggtctgta
     9481 tgtgattggt gtagcgaaag atatcgctca aagtctggcg catcttgatg caatttccgc
     9541 agccaatgct gtgacggtta tttccatcgc caacctttct ggtcgtctgg tgctgggcat
     9601 tctgtctgac aaaatcgccc gtatccgtgt tatcaccatt ggtcaggtga ttgcgctggt
     9661 gggtatggcg gccctgctgt ttgcaccatt gaatgcagtg acgttctttg cagcgattgc
     9721 ctgtgtggca tttaactttg gtggcacgat tacggtgttc ccgtcactgg tcagtgagtt
     9781 cttcggcctc aataacctgg cgaaaaacta cggcgtcatt tacctcggtt tcggtatcgg
     9841 cagcatttgt ggttcgatta tcgcttcact gtttggcgga ttctatgtga ctttctacgt
     9901 gattttcgcc ctgctgattc tgtcactggc gctttctacg accattcgcc agccagagca
     9961 gaaaatgttg cgtgaggcgc atggctccct ttaatgctca gccgtgagct actgggcttc
    10021 agcttcagtg tgcatcaaac gcatcaacga aatgtataaa caataacgcg taaaatttgg
    10081 gccagttaac tggccctttt tactgctttt tgtaacgcta aagtctcttt tcaaacttgc
    10141 atttttgtaa atttgtgctt cgtgcacact ctttccccac actttttccc tttgctgtgg
    10201 tctacttatt cgcgcgtgta gattttactt atctgactac ctccgcactt ttcccctgcc
    10261 tggcctgaaa agccactaag cagggtgtta tcacctgttt gtccagggtt tgtttgcatg
    10321 agatacatca aatcgattac acagcagaag ctgagctttt tgcttgcaat ctatattggc
    10381 ctttttatga atggcgcggt tttttaccgc cgctttggca gctatgcgca cgattttacc
    10441 gtctggaaag gcatttctgc tgttgttgaa ctggccgcca ccgtactggt gaccttcttt
    10501 ttactgcgtc tgctttcgct gtttggccgc cgcagctggc gtattctggc atcgctggtg
    10561 gtgctctttt ctgcaggtgc cagctattac atgaccttcc ttaatgtagt cattggttat
    10621 ggcatcatcg catccgtcat gaccaccgat atcgacctgt caaaagaagt tgttggtctg
    10681 aactttattc tctggttaat cgccgtaagc gcgttgcctc ttatccttat ctggaataac
    10741 cgctgtcgtt acaccttgct ccgacaactg cgaaccccag ggcaacgtat tcgcagcctg
    10801 gcggtcgtcg tactggcagg tattatggtt tgggcaccga ttcgtttgct ggatatccag
    10861 cagaagaaag tggagagggc gacaggtgtt gatttgccga gttatggcgg cgtcgtcgcg
    10921 aactcttatc tgccatcaaa ctggctttcg gcattaggtc tttatgcctg ggcgcgggtc
    10981 gatgaatctt ccgataacaa ttctctcctt aaccctgcga agaagtttac gtaccaggct
    11041 ccacaaaacg ttgatgatac atatgtcgtt ttcattattg gtgaaaccac gcgctgggat
    11101 catatgggca ttttcggcta tgaacgcaat accacaccga aactggctca ggagaaaaat
    11161 ctggcggcgt tccgtggtta ctcctgtgat actgcaacca aactctcact gcgttgcatg
    11221 tttgtacgtc agggtggagc agaagataat ccgcagcgca cattaaaaga acagaacatt
    11281 ttcgcggtat tgaagcagtt aggattcagt tctgatctct acgctatgca aagcgaaatg
    11341 tggttctaca gcaatacgat ggcggacaac attgcttatc gtgagcagat tggtgcggag
    11401 ccacgtaacc gtggcaaacc ggtagatgat atgttgctgg tagacgaaat gcagcaatcg
    11461 ctggggcgca acccggatgg taagcatctg atcattctgc ataccaaagg ctcacacttt
    11521 aactacaccc agcgttaccc gcgcagcttt gcgcagtgga agccggaatg tattggtgtt
    11581 gatagcggct gtaccaaagc gcagatgatc aactcatacg acaactcggt gacctatgtg
    11641 gatcacttta tttccagcgt gattgatcag gttcgcgata agaaagcgat tgtgttctat
    11701 gcagctgacc acggtgagtc aattaatgaa cgcgagcacc tgcacggcac gccgcgtgaa
    11761 ctggcaccgc cggaacagtt ccgtgtgccg atgatggtct ggatgtcgga taaatatctg
    11821 gaaaatccgg tcaatgcgca ggcatttgcg cagctgaaaa aagaagccga catgaaagtg
    11881 ccacgccgtc atgtagagct gtacgacacc atcatgggtt gtcttggcta tacttcaccg
    11941 gatggtggaa ttaacgaaaa caacaactgg tgccacatcc cgcaggcaag agaggcggcg
    12001 gctaactaag aggcctgctg actttctcgc cgatcaaaag gcattttgct attaagggat
    12061 tgacgagggc gtatctgcgc agtaagatgc gccccgcatt cggtgattgg cgcagcctgg
    12121 tagcgcactt cgttcgggac gaaggggtcg gaggttcgaa tcctctatca ccgaccaaat
    12181 tcgaaaagcc tgctcaacga gcaggctttt ttgcatctgt aactcatgag gaagagaacc
    12241 cccgggggcg gggaggttcg actcgacgta ggcctgataa gacgcaccag cgtcgcatca
    12301 ggcaaatgta ccggcccatt gtcggatgcg gcgcgaccgc cttatccgat ctacacacca
    12361 cacatttccc tgtcaaattt gcgccccata tctcactatc cattaacgga tttgtgacag
    12421 aaaccattgt ctttttttat atttgcttaa atcttttttt gcgttactta tggctggcgc
    12481 tggcattttc cgctgtgcgt tttagcgttc atggtattaa tcgctcagat atccaccttt
    12541 acctcagatt tttttcatta aatgcataaa acttaatcac caaatgttgc taaatattaa
    12601 gctgattgtt ctggttgtgt tggcgtagca caaatttctc tgctgcaaat agctgtttga
    12661 agttttttta atctttgttt gtggattctc accgttggtg taaatcccgg ttggctgtat
    12721 tgacgttttc acattctgtt gacagattgt aggtcacgag gggcatttta tggaggatcc
    12781 gcactgttac actgatgtta attagtacgg catccccacc tcataacgtt gacccgaccg
    12841 ggcaaaaaac aaaaaaggtc aggcagcgac aacccactgc aaagggttaa aacaacaaac
    12901 atcacaattg gagcagaata atgcgtattt ccttgaaaaa gtcagggatg ctgaagcttg
    12961 gtctcagcct ggtggctatg accgtcgcag caagtgttca ggctaaaact ctggtttatt
    13021 gctcagaagg atctccggaa gggtttaacc cgcagctgtt tacctccggc accacctatg
    13081 acgcctcttc cgtaccgctt tataaccgtc tggttgaatt taaaatcggc accactgaag
    13141 tcatcccggg cctcgctgaa aagtgggaag tcagtgaaga cggtaaaacc tataccttcc
    13201 atctgcgtaa aggtgtgaag tggcacgaca ataaagaatt caaaccgacg cgcgaactga
    13261 atgccgatga tgtagtgttc tcgttcgatc gtcagaaaaa cgcgcaaaac ccgtaccata
    13321 aagtctctgg cggcagctac gaatacttcg aaggcatggg cttgccagag ctgatcagcg
    13381 aagtgaaaaa ggtggacgat aacaccgttc agtttgtgct gactcgcccg gaagcgccgt
    13441 tcctcgctga cctggcaatg gacttcgcct ctattctgtc aaaagaatat gctgacgcga
    13501 tgatgaaagc cggtacaccg gaaaaactgg acctcaaccc aatcggtacc ggcccgttcc
    13561 agttacagca gtaccagaaa gattcccgta ttcgctataa agcgtttgat ggctactggg
    13621 gcaccaaacc gaagatcgat acgctggtct tctctattac tcctgacgct tccgtgcgtt
    13681 acgcgaaatt gcagaagaac gaatgccagg tgatgccgta cccgaacccg gcagatatcg
    13741 cccgcatgaa gcaggataaa tccatcaacc tgatggaaat gccggggctg aacgtcggtt
    13801 atctctcgta taacgtgcag aaaaaaccac tggatgacgt gaaagttcgc caggctctga
    13861 cctacgcggt gaacaaagac gccatcatca aagcggttta tcagggcgcg ggcgtatcag
    13921 cgaaaaacct gatcccgcca accatgtggg gctataacga cgacgttcag gactacactt
    13981 acgatcctga aaaagcgaaa gccttgctga aagaagcggg tctggaaaaa ggtttctcca
    14041 tcgacctgtg ggcaatgccg gtacaacgtc cgtataaccc gaatgctcgc cgcatggcgg
    14101 agatgattca ggcagactgg gcgaaagtgg gcgtgcaggc caaaatcgtc acctacgaat
    14161 ggggtgagta cctcaagcgt gcgaaagatg gcgagcatca gacggtaatg atgggctgga
    14221 ctggcgataa cggggatccg gataacttct tcgccaccct gttcagctgc gccgcctctg
    14281 aacaaggctc caactactca aaatggtgct acaaaccgtt tgaagatctg attcaaccgg
    14341 cgcgtgctac cgacgaccac aataaacgtg ttgaactgta caaacaagca caggtcgtga
    14401 tgcacgatca ggctccggca ctgatcatcg ctcactccac cgtgtttgaa ccggtacgca
    14461 aagaagttaa aggctatgtg gttgatccat taggcaaaca tcacttcgaa aatgtctcta
    14521 tcgaataatt aaagccatac aagactgatg gcaaaggcaa aactgcctga tgcgctccgc
    14581 ttatcaggcc tacgaaaact ctgcaatgta ttgagtttgc acgattttgt aggtcggata
    14641 aggcgtttgc gccgcatccg gcataaacaa agcgctcttt gtcaacaatc tgcatacccg
    14701 gtggcgctgt gcctctgcgt gcagcgccat ccggcagcaa tacttcattc cctgtcccac
    14761 aagggcggga attgatttgt gagcaataca gacacgcagt tccaggctgc gggtcactat
    14821 agagaatccg ggttatgttg cagtttattc tccgacgttt gggactcgtc atccccacgt
    14881 ttatcggtat tacccttctc acatttgcct ttgtccacat gatcccgggc gatccggtga
    14941 tgatcatggc gggcgaacgt gggatctccc cagagcgtca cgcgcaattg ctggctgaac
    15001 tcggcttaga taaaccgatg tggcagcagt atctccatta catttggggc gtaatgcacg
    15061 gtgatttagg catttccatg aaaagccgaa ttccggtatg ggaagagttc gtgccgcgct
    15121 ttcaggccac gctggaactt ggcgtctgcg cgatgatttt tgcgaccgca gtcgggattc
    15181 cggttggtgt gctggctgcg gttaaacgtg gttccatttt cgatcacaca gcggttggcc
    15241 tggcgctgac cggctactcg atgccaattt tctggtgggg catgatgttg atcatgctgg
    15301 tttcggtgca ctggaacctg acgcctgtct ccggtcgcgt gagcgacatg gtgttcctcg
    15361 atgattccaa tccgttaacc ggttttatgc tgatcgacac cgccatctgg ggtgaagacg
    15421 gtaactttat cgatgccgtc gcccatatga tcctgcccgc cattgtgctg ggtactattc
    15481 cgctggcggt cattgtgcgt atgacgcgct cctcgatgct ggaagtgctg ggcgaagatt
    15541 atatccgcac cgcgcgtgcc aaaggtctta cccggatgcg ggtgattatc gtccatgcgc
    15601 tgcgtaacgc gatgctgccg gtggtgaccg ttatcggcct gcaggtggga acattgctgg
    15661 cgggggcgat tctgactgaa accatcttct cgtggccggg tctggggcgc tggttgattg
    15721 acgcactgca acgccgcgat tatccggtag tgcagggcgg cgtattgctg gtggcgacga
    15781 tgattatcct cgtcaacctg ctggtcgatc tgctgtacgg cgtggtgaac ccgcgtattc
    15841 gtcataagaa gtaagggggc atcatgtcac aggttactga aaataaagtg attagcgcac
    15901 cggtgccgat gaccccgtta caggagttct ggcactattt taaacgcaac aaaggcgcgg
    15961 ttgtcgggct ggtttacgtc gtcatcgtgc tgtttatcgc gatctttgcc aactggattg
    16021 caccctataa cccagcggaa cagttccgcg atgcactgct tgccccgcct gcctggcagg
    16081 aaggcggcag catggcgcac ttgctgggca ctgatgacgt ggggcgtgat gtgctgtcgc
    16141 ggctgatgta cggcgcgcgc ttgtcgctgc tggttggctg tctggtagtg gtgttatcgc
    16201 tgattatggg cgttattctc ggcctgatcg ctggttactt tggcggtctg gtcgataaca
    16261 tcatcatgcg cgtggtcgat atcatgctgg cgctgccaag tctactgctg gcactggtgc
    16321 tggtggcgat tttcggcccg tcgattggta acgccgcgct ggcgctaacc ttcgttgcgc
    16381 tgccgcatta tgtgcgctta acccgcgccg ccgtgctggt ggaagttaac cgcgattacg
    16441 tcaccgcgtc tcgcgtggcg ggtgccgggg caatgcgcca gatgtttatt aacatcttcc
    16501 cgaactgcct tgcgccgctg attgttcagg cgtcgctcgg tttctctaac gccattctcg
    16561 atatggctgc tcttggtttc ctcggcatgg gcgcgcagcc gccaacgccg gagtggggca
    16621 ccatgctctc tgacgtgttg cagttcgcgc aaagcgcctg gtgggtcgtg accttcccgg
    16681 gtctggcgat cctgctgacg gtgctggcat ttaacctgat gggtgacggt ctgcgtgacg
    16741 cgctcgatcc caaactgaag cagtaagagg ttcgagatgg cgttattaaa tgtagataaa
    16801 ttatcggtgc atttcggcga cgaaagcgca ccgttccgcg ctgtagaccg catcagctac
    16861 agcgtaaaac agggtgaagt ggtcgggatt gtgggtgagt ccggctctgg taaatcggtc
    16921 agttcgctgg cgattatggg gctgattgat tatccgggcc gcgtaatggc ggaaaagctg
    16981 gagtttaacg gtcaggattt gcagcgtatc tcagaaaaag agcgccgcaa cctggtgggt
    17041 gccgaagtgg caatgatctt ccaggacccg atgaccagcc ttaacccgtg ctacaccgtg
    17101 ggtttccaga ttatggaagc gattaaggtg catcaaggcg gcaacaaaag tacccgccgt
    17161 cagcgagcga ttgacctgct gaatctggtc ggtattcccg atccggcatc gcgtctggat
    17221 gtttacccgc atcagctttc cggcggcatg agccagcgcg tgatgatcgc catggcgatt
    17281 gcctgtcggc caaaactgct gattgccgat gaaccaacca ctgcgctgga cgtgaccatt
    17341 caggcgcaaa ttatcgaact gctgctggag ctacagcaga aagagaacat ggcgctggtg
    17401 ttaattaccc atgacctggc gctggtggcg gaagcggcac ataaaattat cgtgatgtat
    17461 gcaggccagg tagtagaaac gggcgatgcg cacgctatct tccatgcgcc gcgtcacccg
    17521 tatactcagg cattgctgcg tgcgctgccg gaatttgctc aggacaaaga acgtctggcg
    17581 tcgttgccag gtgtcgttcc cggcaagtac gaccgcccga acggctgcct gcttaacccg
    17641 cgctgcccct acgccactga caaatgccgt gctgaagaac cggcgctgaa tatgctcgct
    17701 gacgggcgtc agtccaaatg ccattaccca cttgatgatg ccgggaggcc gacactatga
    17761 gtacgcatga ggccaccccg caacaaccgc tgttgcaggc tatcgacctg aaaaaacatt
    17821 atccggtgaa gaaaggcatg ttcgcgccgg aacgtctggt gaaggcgctg gatggcgttt
    17881 cgtttaacct tgaacgtggc aaaacgctgg cagtagtagg tgaatctggc tgcggtaaat
    17941 cgaccctagg tcggttgctg acgatgattg aaacgcccac cggcggcgaa ctgtattacc
    18001 aggggcagga tctgctcaag cacgatccgc aggcgcagaa gctacgtcgg cagaaaatcc
    18061 agattgtctt ccagaaccct tacggttcgc tgaatccgcg taaaaaagtt gggcagattc
    18121 tcgaagagcc gctgctgatc aacaccagct taagcaaaga acagcgtcgg gaaaaagccc
    18181 tgtcgatgat ggcgaaagtc ggcctgaaaa ccgagcatta tgaccgctat ccgcatatgt
    18241 tctccggcgg tcagcgtcag cgtatcgcca ttgcccgagg tctgatgctc gacccggatg
    18301 tggtgattgc cgatgagccg gtttccgcgc tggacgtctc agtgcgtgcg caggtgctga
    18361 atctgatgat ggatttgcag caggaactgg ggctatctta tgtctttatc tcgcacgatc
    18421 tgtcggtggt ggagcacatt gctgatgaag tgatggtgat gtacctgggc cgctgcgtgg
    18481 agaaggggac gaaggaccaa atcttcaata acccgcgcca cccgtacact caggcgctgc
    18541 tctccgcgac accacgcctg aacccggacg atcgtcgcga acgcatcaaa cttaccggtg
    18601 aactgccaag cccgctgaat ccaccgccag gctgcgcctt caacgcccgc tgtcgtcggc
    18661 gcttcggccc ctgcatccag ttgcagccgc agctaaaaga ctacggcggt caactggtag
    18721 cttgttttgc cgttgatcag gatgaaaatc cgcagcgtta actcacaaaa ccggggccat
    18781 gcgctccggt ttactcaatc aacttcaaca gtggcgacaa gcataacaaa atgccgtaca
    18841 gcagaatcat ccaggcttta aacccgcgaa gtttttccag ttgtgagact ttatagatca
    18901 ggaaaaacgg aatgaggcac gacacaatgc catataacgg gcttcccaac tgaaagaaca
    18961 ccagtaccga tacacgaaac gaaacccaaa tcgtcaacgt aatgacgata aaagtgcaga
    19021 tcgccagagt cagcacgcgt gagttaattt tcctggtatc aataattcgg cttaacagat
    19081 tgagaataat gcctttaatg gcctcgtgga aaccgagata aatgccaaag aatgcagtca
    19141 gtacggcaaa gatattcagc accgtagagg tgatatgaat gatatgccca gggatcacct
    19201 gcgcggccag tgccagtgcc gagatatttt gttcaaaggc agaaacggct tcttcgtggc
    19261 taattgagaa ggtaaacgaa aaggcaaaaa acaggatcac cgcgatgagc gtgacataac
    19321 taattcggtg ggtacgcagc gcgagccggg ttgccagtac tttatccgct tcccgtttac
    19381 gataggcaat attcattggg ttaagtacct gaataaatac cgcggaaaag aagcaaaatg
    19441 gaatagtaag caggacatcg cggaaaaagt cggaggcttg cgggaaggcg gttatattgg
    19501 cgaaattcca gtgcgggatc atcgcaaaac cgaacacgac aataatccct actttgacca
    19561 ccaccattgg tccggaaatc ttaaacagta atcgttcacc accagacgca atcgccacca
    19621 gtacggcgaa aatggcgact ttataaaata gagattgaga aagatcggca tcggttaaac
    19681 cgaaggtttt caggtacgag gcgctgtcga aaaccacgga gagagagtag ataaaaatcc
    19741 cgtggataat catcaaaaag tagataaccc cgaggaaaat tccccagttc ttccccaggt
    19801 aatgactgat aatatcggtg tagtcattac aggaatcgct ttcagaaagg gtttttaaat
    19861 aaatgtcctg tactacccag gtggcaggat aagcaatgat cgctgcggta ataaataccc
    19921 aaattccctt caagccaatt tgtactggca tcagcacggt tccggcacca atcgccatgc
    19981 ctatgcataa taaaacccag ccgaagtcgt agcgtgtaaa cggcaatttc tgatcgtgtt
    20041 tcggtagtgt gttgtgctgc ataaagtcct gtccagaaag aagtcggcct cgcaaaaatg
    20101 aataaaccca gtttctcttg cgcaacaggt ggagaagtcg aatacgcagt atgtaaaaaa
    20161 tgaggcaaca gattcactgg ggaggtcgcg aggaggcgca attctacaaa attgcgcatt
    20221 tcactactag tctggagtca gcccggatat gagctgcaac tattgcaaat aaagaaatta
    20281 agctggaagg catcacgcaa tgaggaagat tgccgggtgc tgacggcaaa aagcaatcgt
    20341 aaaatcagcg gcaagccgga agggttccgg tgaggcgcaa tgttgcgggg gctttatccc
    20401 tggtggcatt ggttgctgga gagagaaaac ccccgcacgt tgcaggtatg cacctgacaa
    20461 catcacgggg gccattcttg catctagacc a
//
LOCUS       DAPOXO010000089        20401 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.089, whole genome shotgun sequence.
ACCESSION   DAPOXO010000089 DAPOXO010000000
VERSION     DAPOXO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20401
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.089"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(1..759)
                     /gene="aroD"
                     /locus_tag="ROH59_003969"
     CDS             complement(1..759)
                     /gene="aroD"
                     /locus_tag="ROH59_003969"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDX4806394.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDI
                     LEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(790..1656)
                     /gene="ydiB"
                     /locus_tag="ROH59_003970"
     CDS             complement(790..1656)
                     /gene="ydiB"
                     /locus_tag="ROH59_003970"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HDX4806395.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEV
                     DNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMEPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(1668..2933)
                     /locus_tag="ROH59_003971"
     CDS             complement(1668..2933)
                     /locus_tag="ROH59_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806396.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMTSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYCLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVANELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGEHKFSTRLNTIKHRG"
     gene            complement(3160..4374)
                     /locus_tag="ROH59_003972"
     CDS             complement(3160..4374)
                     /locus_tag="ROH59_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806397.1"
                     /translation="MKNPYYPTALGLYFNYLVHGMGVILMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILHTNNIIIAYVFG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGRHLPVIKKTTSSTEHRCSIIDLASYSLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFISFIALLTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFILALFIGLRSRKETR
                     HHTLKENIAPGG"
     gene            complement(4474..4830)
                     /locus_tag="ROH59_003973"
     CDS             complement(4474..4830)
                     /locus_tag="ROH59_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707588.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HDX4806398.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGNSESWRQWENGKCAIP
                     DYVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQQVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
     gene            complement(4966..5073)
                     /gene="rprA"
                     /locus_tag="ROH59_003974"
     ncRNA           complement(4966..5073)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="ROH59_003974"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(5259..6371)
                     /gene="ydiK"
                     /locus_tag="ROH59_003975"
     CDS             complement(5259..6371)
                     /gene="ydiK"
                     /locus_tag="ROH59_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HDX4806399.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKSNK"
     gene            6585..9641
                     /locus_tag="ROH59_003976"
     CDS             6585..9641
                     /locus_tag="ROH59_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDX4806400.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDKEMLGLNIVEFAGDDEALIDERVNALCVRLDELIASQQAGVIGWQVCREL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTFDRQIPI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLEALNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLALGEERGEFNVLLANEWLASALESQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEAKNHKNSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            9638..10048
                     /gene="menI"
                     /locus_tag="ROH59_003977"
     CDS             9638..10048
                     /gene="menI"
                     /locus_tag="ROH59_003977"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HDX4806401.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGLLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSVREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            10148..10336
                     /locus_tag="ROH59_003978"
     CDS             10148..10336
                     /locus_tag="ROH59_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HDX4806402.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            10885..11253
                     /gene="sufA"
                     /locus_tag="ROH59_003979"
     CDS             10885..11253
                     /gene="sufA"
                     /locus_tag="ROH59_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HDX4806403.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMIGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            11262..12749
                     /gene="sufB"
                     /locus_tag="ROH59_003980"
     CDS             11262..12749
                     /gene="sufB"
                     /locus_tag="ROH59_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDX4806404.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYHAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDN
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTVISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            12759..13505
                     /gene="sufC"
                     /locus_tag="ROH59_003981"
     CDS             12759..13505
                     /gene="sufC"
                     /locus_tag="ROH59_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDX4806405.1"
                     /translation="MLSIKDLHVSVEDKAILRGLSLDVRPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTSGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ"
     gene            13480..14751
                     /gene="sufD"
                     /locus_tag="ROH59_003982"
     CDS             13480..14751
                     /gene="sufD"
                     /locus_tag="ROH59_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDX4806406.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGAKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLDGLTNSQFVCIAGEISPQQRDALALTLDAVRLVFVDGRYVPALSDATE
                     GSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPTKPLLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPLSHHFAHNDLLLADDATAFSHSFLLGGAVLRHNTSTQLNGENSTVRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQMFYLRSRGINQQDAQQMIIYA
                     FAAELTEALCDEGLKQQVMARIGQRLPGGAR"
     gene            14748..15968
                     /gene="sufS"
                     /locus_tag="ROH59_003983"
                     /pseudo
     CDS             14748..15968
                     /gene="sufS"
                     /locus_tag="ROH59_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310414.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
     gene            15981..16397
                     /gene="sufE"
                     /locus_tag="ROH59_003984"
     CDS             15981..16397
                     /gene="sufE"
                     /locus_tag="ROH59_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HDX4806407.1"
                     /translation="MAVLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDKSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            16545..17549
                     /gene="ldtE"
                     /locus_tag="ROH59_003985"
     CDS             16545..17549
                     /gene="ldtE"
                     /locus_tag="ROH59_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HDX4806408.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVAVSSGATPAASNAPSVESAQNGEPEQGNMLRATQ
                     "
     gene            complement(17612..17848)
                     /gene="lpp"
                     /locus_tag="ROH59_003986"
     CDS             complement(17612..17848)
                     /gene="lpp"
                     /locus_tag="ROH59_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HDX4806409.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
     gene            complement(18159..19571)
                     /gene="pykF"
                     /locus_tag="ROH59_003987"
     CDS             complement(18159..19571)
                     /gene="pykF"
                     /locus_tag="ROH59_003987"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HDX4806410.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVV
                     MVSGALVPSGTTNTASVHVL"
     gene            20128..20337
                     /gene="fumD"
                     /locus_tag="ROH59_003988"
     CDS             20128..20337
                     /gene="fumD"
                     /locus_tag="ROH59_003988"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase FumD"
                     /protein_id="HDX4806411.1"
                     /translation="MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTA
                     LANKRIQRSELEKQAMETVINALVK"
BASE COUNT         5347 a         4846 c         5227 g         4981 t
ORIGIN      
        1 ttatgcctga tgtaaaatag ttaataccgt acgcaaatca tttaccgaga tttgccctgg
       61 cgcagaggct ttttttaccg caccaaaagt tgccgccgac ccaaatactt caccagccag
      121 acgagaaatt acgccagttt ttgccatcga catcgtgatg attggacgat cggcatactg
      181 ctcctgcatc tccagggtcg cggcaagcaa cgtcagcaca tcgctggtac tttgcggcat
      241 cagcgcaatc ttaggaatat cggcgtcgaa ggactgcatt ttgcgcagac gggcaatgat
      301 ttcttcggct tccggcgttt tatggaagtc atggttggac atgacaactt tcacatcatg
      361 cgcgtgggcg taggcgacgg tttctttaac ctgatcatcg ccggtaaata actccagatc
      421 gatcatatca accaggccgc tgtcgatggc tgcacgattg agtgcaatat aagcctcggt
      481 ggaaatcgcc tgctcgccgc cttctttggc actgcggaag gtaaacagca gcggtttttc
      541 tggcatggtt tcacggagaa tttttgctgc cgccatgaca gactccacat tggagaggtc
      601 ggcatagtgg tccacacgcc attccagaat atcaaagtcc gcttcacgat aggcgagagc
      661 ttcggatttc acgctggcga tatctttcgc catcagcgag acgatgattt taggtgcgcc
      721 cgtaccaatg acgagatctt ttacagttac ggttttcatt ttttaccctt tctgcacgcg
      781 gtcagcctgt caggcaccga accccatgac ctgtttaaca tattccagag ggaaatcttt
      841 gccagtccat aacgtgaact gttcagcccc ttgccacaac aacatgccgt atccatcaat
      901 cgttttgcaa cccgcttgtt gcgcctgctg caataacttc gtcatatgag ggttatacac
      961 gcattcagtg accagaagtc ccgggtgtaa cagactgata tcattaacca atgattcatt
     1021 ctcaaggggt tccataccca ctttggtgcc attggttaaa atgtcggcgg aagccagggc
     1081 ttctgcaaag gcttgctgat cggcgagatc ggtgactgtc acgacgcaat cggtgttttc
     1141 gttaacccgc tgcgcgaagg cgagagcttt atcgaagaac tcatcccgac ggttaaagag
     1201 tttaatttct tttaaacctt caattgcccc ctgcgcgcca attgccgttg aggcaccacc
     1261 ggcccctaat agcaccatcg ttttgccttt gatatcaaaa ccgctctctt taatggcgcg
     1321 aatatgaccc gtgccgtcgg tgttatagcc acgcagatag ccatcatcat ttacgatggt
     1381 gttgatggca cccaccagtt tggccgctgg cgttaattca tcaacatatt cacacgccag
     1441 ttgtttgttc ggcattgata caccagttcc gcgcattttg agggctttta atccttcaat
     1501 tgctccggga aaactatcgt tatccacttc aaaggccata taggtaaatg gcaatcccgc
     1561 tttttctaag gctttattct gcatttcggg cgataaactg tggcggatgg gataggccat
     1621 caacccaatc aattcgtatt ttgcggtaac atccataatt aactccttta acctctatgc
     1681 ttaattgtgt ttaaccgggt gctaaattta tgctcgccaa accgcacatc attttcagga
     1741 ataatgaaaa cgcggtaata gcggataaaa acaataattg cggtaatcag ggccagcagc
     1801 gcgaaagtaa aatcgagaac aatgatatat tgcaggccga tgttcgacag ataaccggta
     1861 atcagcggaa taacaaagtt agccagtcca cccatcatca tatatatact ggtgactttg
     1921 gctttgcttt ttgggaaaaa ctctgacatg accgaaacgc cgagctgtaa aatgccgcca
     1981 gctgctgaga aaccgataac aaaggctccg gcattacaca ccaatggaga tgggtacagg
     2041 tagataatgg cagctgttat tgttgccagt gcagagttaa atacattagc ccagatgggc
     2101 cggaccattt ttttcagcag tgcggcaaaa ataaagacac agaccagcga acccatactg
     2161 taataagaga tggtttttaa tgcctcagct tctgacatac cagcaaaagc catcgcatat
     2221 ttgggcatcc acaccacaat cacataaaag gtcgagaatg cggctacacc gaacagtact
     2281 gatgaaacac cttccagcca gactaacggt ttgctgttca tttgcggtaa ttcattagct
     2341 acgctggcgt ccaccaactg gctggggaat ttgcttttca acagcatcag cgtgatcagt
     2401 acaaacagaa tacccggaat aatcagccca tagccgtacc agatgttatt gagcaacata
     2461 tagctcacca gcattggata gaacatttgc ccgaatgaca ccatcgcttt aaccagtatg
     2521 accgccgaac cagaggcttt cggaaagcat tccatgagcg cggggtagcc acccgtatcc
     2581 agcgctgagt tagcgatacc tacgcacact gccagacagt aggcgagagt taaattcggg
     2641 caagcaggaa taccaaagaa gaatagcaga tacattatta ctgccattaa tatcaccgcc
     2701 cgacgaccaa acttatcgga gatcactccg aagaataaaa tactgatcaa tcgccccaat
     2761 ccgataccgg aaattaaata ggcaatgccc gcgttgtcag tggaaaactt ttctgccaaa
     2821 gatgtcatgt tttgggcaag cgtaataaca ctaatgccgt gcaggaaata gctgaagtaa
     2881 atacaaagaa cagccaggat aaatggcgtg ctgaaagcct tattttgaga catgttcaca
     2941 gctccttgct gaaagataat ttcgttaccg tacgtattgt tctccgacgg tttacataat
     3001 tactatactg aagatgattt tccctgggta catggcataa agtttatgtt tccaggaata
     3061 ttgcatgtca tagtttgttt ttgatcgcta ttttccttag ttagcgcaga aagagttatt
     3121 tatccgtaag atcttgcata acctgaaaag aatattgcat tacccacccg gagcgatatt
     3181 ttcctttagc gtgtgatgcc gcgtttcttt gcgactgcgt aagccaataa acagtgccag
     3241 tataaagccg atagcagcga tggcggtatc gaaccacata atatcggcaa tacttctttg
     3301 cgaaagatga gccgtaatca acggaatggt aaatgttgca atgctgcccg cactgtaata
     3361 gatccccgta gctttacctt tagcgtaggg aaaacgttcc gccattaacg tcaggccaat
     3421 ttgtacaaca ccgcctgcgg aggtaaaacc gatgacgaaa gcaaatatta tcaccacata
     3481 aaatgtggga tgcaggcaga cggtgagcag ggcgataaat gagataaagg tgtacagcat
     3541 cagtaatgtt gttgggcgaa cggtattacg aatgagtgga gcagtaataa atacacacag
     3601 cagcgaaccc acggtgtaga tactgagtaa tttgatcgac atggtgtatg acatgccagc
     3661 gacaaattgt ccgtattgtg ccagccactg gctaaccaga taaaacgttg ccattgagat
     3721 atagccatat agggaataac tggctaaatc gataattgaa cagcgatgtt ccgtagagct
     3781 ggtggttttc tttatgacag gtaagtgacg acccggatgg ggtgggaacg tacaacggta
     3841 taaaaacaga gcgttaataa acataatgcc tgcggcaatc ataaaggacc aaccgaacca
     3901 cagttcagcc cacactaaca ggctgataat tagcggtaat aaaaattgtc cgctggaaac
     3961 aaatgcttta attaaaatat tggctgtacc cggtgagcgt ggaaaagctt ccatcaaact
     4021 gggataggtg cctgcatcga gaaaactgtt tgccattccc gccagaaagc caaaaacata
     4081 agcgataatg atgttattgg tgtgcaggat gccaaaaaag aaggccatat agcagcacat
     4141 cccgagcatg ataaaagggc ggcgaccaaa gcgatcggat aataatcctg caaaaagcaa
     4201 gacacttaat cgaccaatgc ccagtgatga gataactatc gagacgcccg cggcattagt
     4261 ctgccaaagc gtctccagcg aggccatatt caggctcatc aaaatgacgc ccataccatg
     4321 caccaggtaa ttaaaataca acccaagtgc ggtagggtaa tagggatttt tcataggttc
     4381 tacttagcaa aggtgcttta aaaagtgtag cgatgttgtg tcagtatccg ttcattattg
     4441 ttgtaacaac gacaattcct ttctgtggag aaattaacaa agccgctcca gatcgtgtgc
     4501 atataattca gcggctaccg attgatagat cttccagtca ataaaattgc catcagggta
     4561 gacttgttga aacgcggtta agtcggggaa aaaacgcatg gtgttgttgc cgatgcggtt
     4621 atttattttc tctatgattg catgaagatg tttttttcgt tgctgacgca tagccaacag
     4681 ttgctcgact acataatcag gaatggcgca tttgccattt tcccactgac gccagctttc
     4741 actgttaccg gtctgggcaa tccaggtcgc gcattcatca atagtcatgg caaaaatatg
     4801 gcgaagtgcc tggagttcat aagcgttcat cgtgtaatgg ctgcatgaaa taaacaataa
     4861 aatataaata acattatcag cctgctgacg gcttgaagag agtcacagta tcttgtgcaa
     4921 cattattgga aagagtgagg ggcgaggtag cgaagcagaa aaatgttaaa aaaaagccca
     4981 tcgtgggaga tgggcaaaga ctacacacag caattcgttg tttcactcag gggatttcca
     5041 tgcttataaa tcaatatgtt gatttataac cgtgagctaa tagtaggcat acggactttt
     5101 tgcgtcgatc agattcgtct cattagttta aaaactgtaa agaatttgcg acaggtacta
     5161 ccagctgaat agcggtaagc aggaaaatat ggggaagagc aagcaaatat caattagcag
     5221 gggttaacaa tcaggcggca gagccgcctg atgagaaatt acttattcga tttctcgatt
     5281 tcgccaagtt cttcgagaat ttcttccggt tggtccgtcg gcggtgggac ttcttccacc
     5341 cacgcggcaa acagacgcca ggaaacggct aacagaaccg gaccaataaa cagaccgatc
     5401 atcccgaaag caatcaaacc accaataacg ccagagagga tcaggatcag cggtaaatcg
     5461 gcacccatgc gaattaacat tgggcggatg acgttatcga gcgtgccaac cacaccgctc
     5521 caaactaaca ataccgttcc ccaggtggta tcgccagtcc agtagagcca gataatcgcc
     5581 ggaatcagta ccggcaacgg tccaagctgg acaaggcagg agaggatcat taacaccgtt
     5641 agcaaagttg cataaggtac gccggatacg gcgaggccga taccgccaag cactgcctgt
     5701 actaacgccg tcaccaccac acccagcgcc accgcgcgga tagcctgtgc cgccagcagc
     5761 acggcggcat ctccgcgaac gcctgccaga cgggttgcaa aatggcgaat gccttgtgcc
     5821 acctgttcac cgcgccagta cagcagggcg ctgaagagaa gcatcagcgc acaatgcacc
     5881 ataaagcgcc cgatatgcgc cgcctgccca acgaaccagg tggtggtggt gccaatataa
     5941 ggacggactt tcgccatgat cgccgtcccc cccatatcca gcaaattgtg ccagcctgca
     6001 tatagcttcg cgccaatcac cggaatggta ttaagccacg ccagatcggg taacgtcatg
     6061 tcaccactgg aaatggcttt aattagcggg ccgctgccgt cgacgatact gttaaccagc
     6121 aaagcaatag ggatgataaa caccatcact aataacagcg tcatcaccag aacggcgaga
     6181 gagcggcgac caaacatgat cttttgcaaa cgtaacaata ccggccaggt ggcgataacc
     6241 actgtaccgg cccatgcaaa gccgagaata aagggttgta caatccacag acatgccaca
     6301 atcatgatgg ctaaaaacag caccgaaagc agaatttgtg cgacatccct gggctgacga
     6361 acatttacca taactacttt tcaccttttt tgtgcgtcaa atcgtcgacg cgacgtgaac
     6421 acgcgaaact cacctgcata atgatgagca atttcagcgg tttttaacag gtcgattctg
     6481 cccttaattc tgatgggcgt gttagaaaaa aatgtggtac aacaactcag gcaacacgca
     6541 aacgattaat ctctcatcac agaccgcagg aaagggtcaa tataatgatt ccacagattt
     6601 cccaggcacc cggcgtcgtt caactggtgc ttaatttttt gcaagagctg gagcaacagg
     6661 gttttaccgg cgatacggcg acaagttatg ccgatcgtct gacaatgtcg actgacaaca
     6721 gtatttacca acttctcccc gatgcggtgg tatttccgcg ttcaaccgca gatgtagcgc
     6781 tgatcgcccg tcttgccgcg caggaacgct attcatcgtt gatctttacc ccccgcggcg
     6841 gcggcaccgg cactaacggt caggcgctca accaggggat tattgttgat atgtcccgcc
     6901 atatgaaccg catcatcgaa attaaccctg aagagggctg ggtgcgcgtt gaggccgggg
     6961 tgattaaaga ccaactcaat cagtacctga aaccctttgg ctactttttt gcgccagaac
     7021 tttcgaccag caaccgggca acgctcggcg ggatgatcaa taccgatgca tccggtcagg
     7081 gatcgctggt ctatggcaaa acgtcagatc acgtacttgg cgtacgcgcg gtgttgttgg
     7141 ggggcgatat tctcgatacg caacctttac ccgtcgaact ggcggaaacg ctgggtaaat
     7201 ccaataccac aatcgggcga atttataaca cggtttatca acgttgccgt cagcaacgcc
     7261 agttaatcat cgacaacttc cccaagctta accgctttct taccggttac gatctgcgtc
     7321 atgtctttaa cgatgagatg accgagttcg acctgacgcg cattctgacg ggttcagaag
     7381 ggacgctggc ctttattacc gaagcgcgac tggatattac gcgcttgcct aaagtacgcc
     7441 gtctggtgaa cgtcaaatat gactcttttg actccgcgct gcgtaacgcg ccgtttatgg
     7501 ttgaggcgcg cgcgctttcg gtagagacgg tggactcaaa agtgctcaac cttgcacggg
     7561 aagatattgt ctggcattcc gtcagcgagt tgattaccga tgtgcctgat aaagagatgc
     7621 ttgggctgaa cattgtggaa tttgccggtg atgatgaggc actgattgac gagcgagtta
     7681 atgcactctg tgtgcggctt gatgagctga ttgccagcca acaggcagga gtgatcggct
     7741 ggcaggtgtg ccgcgagctg gcgggtgttg aacgtatcta tgcgatgcgc aaaaaagccg
     7801 ttggtctgct tggcaatgcc aaaggtgctg ctaagccaat tccgtttgct gaggatacct
     7861 gcgtaccgcc ggaacacctg gcggattata ttgctgaatt tcgcgcgctg ctcgacagcc
     7921 acggcttaag ctacggtatg ttcggtcacg tcgacgcagg tgtcttgcac gtccgtccgg
     7981 cgctggatat gtgcgatccg caacaagaga ttttgatgaa gcaaatctct gatgatgtag
     8041 tggcgcttac cgcgaaatac ggtggtttgt tgtggggcga acacggcaaa ggttttcgcg
     8101 ccgaatacag cccggcgttt ttcggtgagg aactttttgc agaactgcgt aaagtgaaag
     8161 cggcatttga cccgcataac cgactcaacc ccgggaagat ttgcccgcca gaaggtctcg
     8221 atgcgccgat gatgaaagtg gacgcggtga agcgcggtac attcgatcga cagatcccca
     8281 ttgcggtacg ccagcagtgg cgtggtgcaa tggagtgtaa cggcaacggt ttatgcttca
     8341 actttgatgc tcgtagtccg atgtgtccgt cgatgaagat cacccagaac cggattcatt
     8401 caccgaaagg gcgcgctacg ctggtacgtg aatggctgcg tttgttggcg gatcgcggcg
     8461 ttgacccact caaactggaa caagaacttc ctgaatccgg agtcagtttg cggacgttaa
     8521 ttgcccgcac gcgcaatagt tggcatgcga ataaaggcga atatgacttc tcacacgaag
     8581 tcaaagaggc gatgtcgggc tgtctggcct gtaaagcgtg ttcgactcag tgccccatca
     8641 aaattgatgt gccggagttt cgctctcgtt tcctgcaact ctatcacacc cgttatttac
     8701 gcccgctgcg cgaccacctc gtcgctacgg ttgagagtta cgcaccgctg atggcacgcg
     8761 cgccgaaaac ctttaatttc ttcattaacc agccgctggt gcgcaaactc tcggaaaaac
     8821 atatcggcat ggttgatttg ccgctgctgt cggtcccctc gctacaacaa caaatggtgg
     8881 ggcatcgctc ggcaaacatg acgctggaac agcttgaagc tctcaatgca gagcagaaag
     8941 cgcgcacggt gcttgtggtg caggacccct ttaccagcta ttacgatgct caagtggtgg
     9001 cggattttgt ccgtctggtc gaaaaattag gtttccagcc cgtgttactg ccattttcgc
     9061 caaatggcaa agcccagcat atcaaaggtt ttcttaatcg ttttgcgaag acggcgaaaa
     9121 agacggcgga tttcctcaac cgtatggcga agctgggtat gccaatggta ggcgtcgacc
     9181 cggcgctggt actttgttat cgcgatgaat ataaactggc tctgggcgag gagcgtggcg
     9241 agtttaacgt cttactggcg aatgaatggc tggcaagcgc acttgagtca cagccagtgg
     9301 ctacagtcag cggtgaatca tggtatttct ttggtcactg taccgaagtt accgccttgc
     9361 cgggcgcgcc agcacaatgg gcggcaatat ttgcccgttt tggcgcgaaa ctggaaaatg
     9421 tcagcgtggg gtgctgcggc atggcaggga cttacggaca tgaagcgaaa aatcataaaa
     9481 attcgctcgg gatctatgag ttatcctggc atcaggcgat gcagcgactg ccgcgtaatc
     9541 gctgtctggc gaccggatat tcctgccgta gtcaggtaaa acgggttgaa ggcacggggg
     9601 tacgccatcc tgtgcaggct ttactggaga ttattaaatg atatggaaac gaaaaatcac
     9661 cctggaagca ctgaatgcta tgggggaagg aaacatggtg gggttgctgg atattcgctt
     9721 tgaacatatt ggtgatgaca cccttgaagc gacaatgcca gtagactcgc ggacaaagca
     9781 gcctttcggg ttgctgcatg gaggtgcatc cgtggtactg gccgaaagta tcggttccgt
     9841 tgccggttat ttatgtaccg agggtgagca aaaagtggtt ggtctggaaa tcaatgctaa
     9901 ccacgtccgc tcagtacgag aagggcgggt gcgcggcgta tgtaaaccgt tgcatctcgg
     9961 ttcgcgtcac caggtctggc agattgaaat cttcgatgag aaagggcgtt tgtgctgttc
    10021 gtcacgattg acgaccgcta ttttgtgacg ttgtcaccag aaaagtgtga cgcatattgc
    10081 ttttggttat tatctgcaca gtaaacggtg gtatactgtg caggtcttgt ctaaaagcga
    10141 ggatgctatg tctactcaac ttgatcccac ccaactggcc attgaatttt tacgccgtga
    10201 ccaaagcaat ctttcacctg cccaatatct caagcgtctg aaacaattag aacttgaatt
    10261 tgctgacctg cttactctct cttctgctga attaaaagaa gaaatctatt tcgcctggcg
    10321 tctgggcgtg cattgatcct gatttaatgt cgcgagttcg ccaaatcggc ctggattaat
    10381 cttcgtccag gttcgagggc cttcttaata ctgcctatct acccgcctga taacgttcaa
    10441 aaataataca aatcgcagtt tgtgttaaaa cagtgggtta gctttatgag attatcctta
    10501 tcgccccttc aagagctaag ccactgtgag tgccggagat aagcgccgga tggggtagaa
    10561 acccttaagc ctgtgtcgca cagacttaag ggttttctta tttctgaacg ctgcactttt
    10621 ttacctatcc cttaaatagt cattttcaat gcaacttttt ctttttcatc acagccttaa
    10681 tgctccttag ataataatca ttatctaaca atgagatacc taattcttag cgtgcctgtt
    10741 aacccacaaa tcagggtcta tgcttattaa aagcaggtaa aaagcatgtt ttacgctaaa
    10801 gcccctgcgt ttgctgggtt gaactgataa tcattatcac taacatgctg ttatacgctg
    10861 aaagcgatga agtgaggtaa atcgatggac atgcattcag gaacctttaa tccacaggat
    10921 ttcgcctggc aaggcttaac gctgacaccc gcagcggcga tacacatccg cgaactggtg
    10981 gcaaagcagc cgggtatgat cggcgtgcgc ttaggcgtga agcaaacggg ctgcgcgggc
    11041 tttggctatg tgctcgacag tgttagcgag ccggacaaag acgatctgct gtttgaacac
    11101 gacggcgcga agctgtttgt cccgctgcaa gcgatgcctt ttattgatgg cacggaagtc
    11161 gatttcgttc gtgaaggact taatcagata ttcaaatttc acaaccctaa agcccagaat
    11221 gaatgtggct gtggcgaaag ctttggggta taggcggtac tatgtctcgt aatactgaag
    11281 caactgacga tgtcaaaacc tggaccggcg gcccgctgaa ttataaagaa ggattcttca
    11341 cccagttagc caccgatgag ctggcaaagg ggataaacga agaggtggtg cgcgcaattt
    11401 cggcgaagcg taatgagccg gagtggatgc tggagtttcg tctcaacgcc tatcacgcat
    11461 ggctggagat ggaagaaccg cactggttga aagcgcacta cgacaagctg aattatcagg
    11521 attacagcta ctactcggca ccatcgtgcg gtaattgtga cgacaactgc gcgtctgaac
    11581 ccggcgcggt gcagcaaact ggcgcgaacg cctttttaag taaagaggtg gaggcggcgt
    11641 ttgagcagtt gggcgttccc gtgcgggaag gcaaagaggt ggcggtggat gccattttcg
    11701 actctgtttc ggttgccact acttatcgcg aaaaactggc ggagcaggga attatttttt
    11761 gttcctttgg cgaggcgatc cacgatcacc cggaactggt gcgtaaatat ctcggcaccg
    11821 tggtgccggg gaatgacaac ttctttgccg cacttaatgc ggcggtagcc tctgacggta
    11881 cgtttattta tgtgcctaaa ggcgtgcgtt gcccgatgga actttccacc tattttcgca
    11941 ttaacgcgga aaaaaccggg cagtttgagc gcaccattct ggtggccgac gaagacagct
    12001 acgttagcta cattgaaggc tgttccgctc cggtgcgtga cagctatcag ttacacgcgg
    12061 cggtggtgga agtcatcatc cataaaaacg ccgaggtgaa atattctacg gtacaaaact
    12121 ggttccctgg cgataacaac accggcggta ttctcaactt cgtcaccaag cgtgctttgt
    12181 gcgaaggcga aaacagcaaa atgtcatgga cgcaatcaga aaccgggtca gcgattacgt
    12241 ggaaatatcc cagctgcatt ttgcgcggcg ataactccat tggtgagttt tactcagtgg
    12301 cgctgaccag cggtcatcaa caagcggata ccggcaccaa gatgatccac atcggtaaaa
    12361 acaccaaatc gaccgttatc tcgaaaggga tctctgccgg acatagtcag aacagttatc
    12421 gcggcttagt gaaaatcatg ccgacggcaa ccaatgcgcg caatttcact cagtgcgact
    12481 caatgctgat tggcgctaat tgtggggcgc ataccttccc gtatgtcgaa tgtcgcaata
    12541 acagcgctca gctggagcac gaggcaacga catcacgtat tggtgaagat caactgtttt
    12601 actgcctgca acgcgggatc agcgaagaag atgccatctc gatgattgtt aacggttttt
    12661 gcaaagacgt gttctcggaa ctgccgctgg aatttgccgt tgaagcacaa aaactcctcg
    12721 ccatcagcct tgagcatagc gtcggataag gaataaacat gttaagtatt aaagatttac
    12781 acgtcagcgt ggaagataaa gctatcctgc gtggattaag cctcgatgtt cgtcccggcg
    12841 aagttcacgc cattatgggg ccaaacggtt cgggcaaaag taccttatcg gcaacgcttg
    12901 ccgggcgaga agattatgaa gtgacgagcg gcacggttga gtttaaaggc aaagatttgc
    12961 ttgcgctgtc gccggaagat cgtgcaggtg aaggcatctt tatggccttc cagtatccgg
    13021 tggaaattcc cggcgtcagt aaccagtttt tcctgcaaac ggcacttaat gcggtgcgca
    13081 gctatcgcgg ccaggaaacg ctcgaccgct ttgattttca ggatttgatg gaagagaaaa
    13141 tcgctctcct gaagatgccg gaagatttat taacccgttc ggtaaacgtt ggtttttccg
    13201 gcggcgagaa aaagcgcaac gatattttgc aaatggcggt gctggaaccg gagttatgca
    13261 ttcttgatga gtcagactcc gggctggata ttgacgcatt aaaagtggtt gccgatggcg
    13321 tgaactcgct gcgtgacggc aagcgttcat tcatcattgt tacgcactat caacgcattc
    13381 tcgactacat caagcctgat tacgtccatg tgctgtatca gggacgaatt gtgaaatccg
    13441 gcgatttcac gttggtcaaa caactggagg agcagggtta tggctggctt accgaacagc
    13501 agtaacgcac tgcaacagtg gcatcatttg tttgaagctg aaggggcgaa acgctccccg
    13561 caagcacagc agcatttaca acaattgctg cgtaccggac tgccgacacg taaacatgaa
    13621 aactggaaat atacgccgct ggacgggctg accaatagcc agtttgtctg cattgcgggg
    13681 gagatatccc cacagcagcg tgatgcctta gcgttaacgt tagacgccgt gcggctggtg
    13741 tttgtcgatg gacgttacgt gcccgcactg agcgatgcaa ctgaaggcag cggatatgaa
    13801 gtgagcatta acgacgaccg tcaggggtta cccgacgcta ttcaggcgga agtgtttctg
    13861 catttgacgg aaagcctggc acaaagcgtg acgcatatcg ccgtgaagcg cggtcaacgg
    13921 ccgacaaagc cattgctgtt aatgcatatc acccagggcg tggcaggtga agaggtgaat
    13981 actgcccatt accggcatca tctggatctg gcggaaggtg ccgaagcaac ggtgatcgaa
    14041 cattttgtca gccttaatga tgctcgtcac ttcaccggcg cacggttcac tatcaacgtc
    14101 gcagcgaacg cccatttgca gcatatcaag ctggcgtttg aaaacccgct cagtcaccac
    14161 tttgctcata acgatttgtt gctggctgat gatgccaccg catttagcca cagtttcctg
    14221 ctgggtggcg cagtgttacg acacaacacc agtacgcaac tcaatggcga aaacagcacg
    14281 gtgcggatca atagcctggc gatgccggtg aaaaacgagg tgtgtgatac tcgtacctgg
    14341 ctggaacaca ataaaggttt ttgtaacagc cgacagttgc acaaaactat cgtcagcgac
    14401 aaaggccgcg cggtatttaa cggtttgatc aacgtcgcgc agcacgccat caaaacggat
    14461 ggtcagatga ccaacaataa tctgctgatg ggcaaactgg cggaagtgga tactaaaccg
    14521 cagctggaaa tctatgcaga tgatgtgaaa tgcagccacg gcgcgacggt ggggcgtatt
    14581 gatgacgaac agatgtttta tctgcgctcg cgcgggatca atcagcaaga tgcccagcag
    14641 atgatcatct acgcctttgc tgccgaactg acggaagcac tgtgtgatga ggggcttaaa
    14701 cagcaggtga tggcccgaat cggtcaacga ctgccaggag gtgcaagatg actttttccg
    14761 tcgacaaagt gcgggccgac tttccggtgc tttctcgtga ggtaaacggt ttgccgctgg
    14821 cttatctcga cagtgccgcc agtgcgcaga aaccaagcca ggtgattgac gccgaggctg
    14881 agttttatcg tcacggctac gcggcggtgc atcgcggtat tcatacctta agcgcccagg
    14941 cgaccgagaa aatggagaac gtgcgcaagc gggcatcgct gtttattaat gcccgttcgg
    15001 cggaagagct ggtgttcgtc cgcggcacga cggaagggat caatctggtc gccaatagct
    15061 ggggcaacag caatgtgcga gcgggcgata acatcatcat cagtcagatg gagcaccacg
    15121 ctaacattgt cccctggcag atgctttgcg cacgcgttgg cgcagagctg cgtgtgatcc
    15181 cgctcaaccc cgacggtact ctgcaactgg agacgctgcc tacgctgttt gatgagaaaa
    15241 ctcgcctgct ggcaattact catgtctcca acgtgcttgg gacagaaaat ccgctggcgg
    15301 agatgatcac acttgcgcat caacatggcg caaaagtgct ggtggatggc gctcaggcgg
    15361 tgatgcatca tccggtggat gttcaggcgc tggattgcga tttctacgtg ttttccgggc
    15421 ataaactgta tggtcccacc ggcattggcg tgctgtatgt caaagaagcc ttgttgcagg
    15481 agatgccgcc gtgggaaggg ggcggttcta tgattgccac cgttagcctg agtgaaggca
    15541 ctacctggac caaagcgccg tggcggtttg aagccggtac gcccaatacc ggaggtatta
    15601 ttggccttgg cgcggcgctg gagtatgttt cggcgctggg gcttaataac atagccgagt
    15661 atgaacagaa tctgatgcac tacgcgctag cacagctgga atctgtaccg gatctcactc
    15721 tctatggccc atagaacagg cttggcgtta ttgcttttaa tctcggtaaa caccacgcct
    15781 atgatgttgg cagttttctc gataattacg gcattgctgt gcgtaccgga catcactgcg
    15841 ctatgccatt aatggcctat tacaacgtcc ccgcgatgtg tcgggcgtcg ctggcaatgt
    15901 acaacaccca tgaagaagtg gatcgtctgg taactggatt gcaacgtatt catcgtctac
    15961 tggggtaaaa gggaggctct atggctgtat tgccggataa agaaaaattg ctgcgtaact
    16021 ttttacgctg cgccaactgg gaagagaaat atctctacat tattgaactg ggacagcgtc
    16081 tgccagaatt acgtgacgaa gacaaaagcc cgcaaaatag catccagggc tgccagagtc
    16141 aggtgtggat tgtaatgcgc cagaatgcgc agggaattat tgaattgcag ggcgacagcg
    16201 atgcggccat tgtaaaaggg cttattgcgg tcgtctttat tctttacgat caaatgacgc
    16261 cgcaggatat tgtcaatttc gatgtgcgcc cgtggtttga aaaaatggcg ctcacccaac
    16321 atctcacccc atcacgctca caaggtctgg aagcgatgat tcgcgcaatt cgcgccaaag
    16381 ccgctgcact tagctaaact aaagggacag ctttcatccg gttggctcac attgtcgggt
    16441 ggtcaatgtt tacactggcc tgcacaggag tgttttggtt tcaggtgaac taagcgccat
    16501 ccgacgtttc agcgtgagtc tccggcaaat acaggaggtt tacaatgaaa cgcgcgtctt
    16561 tgcttacact cacgcttatc ggcgctttta gcgccatcca ggctgcctgg gcggttgatt
    16621 atccgctacc accaaccggc agccgactgg ttgggcaaaa tcaaacgtat acggtgcaag
    16681 aaggggataa aaaccttcag gccatcgccc gacgttttga tactgcggca atgttgatcc
    16741 ttgaagccaa taacactatc gccccggtgc caaaacccgg tacgacgata actattcctt
    16801 cacaactgtt attacctgat gcaccgcgcc aggggataat tgtgaacctt gcagaactgc
    16861 gcctttatta ttatccgccg ggagaaaata tcgtgcaggt ttatccgata ggtattggtt
    16921 tgcaggggct ggaaacgccg gtgatggaaa cgcgtgtggg gcagaaaatc cctaacccaa
    16981 cctggacgcc tacggcgggc attcgtcaac gttcgctgga gcgtggcatt aaattaccgc
    17041 cggtcgttcc tgccgggcca aataacccgc taggacgtta cgcactgcgc ctcgcgcatg
    17101 gtaatggcga atacctcatt catggcacca gtgcgccgga cagcgtcggt ttgcgcgtca
    17161 gttcgggctg tattcgcatg aatgcaccgg atattaaagc tttattctcc agcgtgcgga
    17221 cgggaacgcc ggtgaaagtg atcaacgaac cggtgaaata ttccgtggaa cctaacggga
    17281 tgcgttatgt tgaagtacat cgaccactat cggcagaaga acagcagaac gttcagacaa
    17341 tgccgtacac gctgccagca ggctttacgc aatttaaaga caataaggct gtagatcaga
    17401 agttagtcga taaagcgttg tatcgtcggg cagggtatcc ggttgcggtg agcagtggag
    17461 caactcccgc agccagcaat gcgccttcag tagagtcagc gcagaatggg gaaccagagc
    17521 aagggaatat gttacgcgcg acgcagtagc ggtaaatagc aggcaaaaaa atggcgcaca
    17581 atgtgcgcca tttttcactt cacaggtact attacttgcg gtatttagta gccatgttgt
    17641 ccagacgctg gttagcacga gctgcgtcat ctttagcagc ctgaacgtcg gaacgcattg
    17701 cgttcacgtc gttgctcagc tggtcaactt tagcgttcag agtctgaacg tcagaagaca
    17761 gctgatcgat tttagcgttg ctggagcaac ctgccagcag agtagaaccc aggattaccg
    17821 cgcccagtac cagtttagta gctttcatta ttaataccct ctagattgag ttaatctcca
    17881 tgtagcgtta caagtattac acaaagtttt ttatgttgag aatatttttt tgatgggaag
    17941 gcacttattt ttgatcgttc gctcaaagaa gcatcgaacg ctgggtttta gataaaaaaa
    18001 ttgagagaaa acaggatgct tccatcggat tcatcttaga taaagtgaga ttatatagtg
    18061 aaatccgatt tgatttttta ttgcttctgg ttatcgatta aataaaaaaa gcgcccatca
    18121 ggacgcttcg atatacaaat taattcacaa aagcaatatt acaggacgtg aacagatgcg
    18181 gtgttagtag tgccgctcgg taccagtgca ccagaaacca taactacgac atcacctttg
    18241 tgtgccagac cgctctgcag agccagttct ttacccagac ggtagaagtc atcagtagaa
    18301 gtgatctctt taaccagctg cggcacaacg cctttgctca gtactaactg gtgagccgtt
    18361 ttttcgttgg tggtcagtgc caggatggtg gcatccggga agtatttacg tactgcgcga
    18421 gcagatttac cgccctgagt agcaaccacg atcagcggag catccagttt ttcagcagtt
    18481 tcaacggcac cacggcatac cgcttcggtt atacgcagtt tacggttgtc attgttgaac
    18541 tcgagacggc tgttcatcac gcggtcggta cgttcgcaga tggtcgccat gatagaaacc
    18601 gcttccagcg ggtatttacc ttttgcggat tcaccagaca gcatcactgc gtcagtaccg
    18661 tcgaggatgg cgtttgcaac gtcaccggct tctgcgcgag tcgggcgtgg gtttttgatc
    18721 atggaatcca gcatctgggt cgcagtgata acgactttac gtgcacggat acatttttcg
    18781 atcatcatct tctgggcgaa gataacttct tctaccggga tttctacacc caggtcgcca
    18841 cgcgcaacca tgatgccgtc agaggcttcg aggatttcgt cgaagttgtt gaggccttcc
    18901 tggttttcga ttttggagat gatgtggatg ttttcgccgc cgtgcgcttt caggtgctca
    18961 cggatttcga taacgtcaga acgcttacga ataaaggaag cagcaacaaa gtctacgcct
    19021 tgttcgcaac caaagatcag gtcctgtttg tctttttcag ccagtgctgg cagggcaatg
    19081 gaaacgccag gcaggttcac acctttgttt tcgcccaggt cgccgttgtt cagcacttta
    19141 cagataactt tgttaccttc aatggcggta acttccatac cgatcagacc gtcgtcaacc
    19201 agtacggtgt tgccaacaga caggtcagta gtgaaacctt catacgttac cgcaaccatt
    19261 tcgctgttgc cgataacaga tttatcagta gtgaaagtaa aggtctgacc cgctttcaga
    19321 gaaacgtcgt taccgccttc cagtttcatg gtgcggattt ccggaccttt ggtatcaagc
    19381 aggatagcgg cggttttacc agttttgctc atcacgttgc gcagattctg aatgcgctga
    19441 ccgtgttctg catagtcacc atgagagaag ttcagacgca taacgttcat gccagcgtcc
    19501 agcattttag ctaacatctc ttcagattcg gttttcggtc cgatggtgca aacaattttg
    19561 gtctttttca tgacagtctt agtctttaag ttgagaagga tgggagaaac ttgctttctg
    19621 ggcgcactgc cggaaagcga atccggtatt acgaaagtgg ttgtgcctcg ctctaaggat
    19681 aggtgacatc gaaaaagcgt gcagaggaat gtgtgcttgt gtctcagccc aacgtgagtg
    19741 cctgtttttg agtcgttgag ttctacagtc caaagtgctg aaaccattca agagtcaatt
    19801 ggcgcgcatt atacgctgaa attaatccaa aaggaaaaca aaaacagcgt ttcaaaaaat
    19861 atacaacttg ttagacaata aattgttatc aaagattcag cgttccaggg aaaaggttac
    19921 gcaaaaactt cgttgtttgc gcaacgtctg gtgccggggt tgtcagtgtg aggataagtg
    19981 aaagttcatc cggtgtataa atacatcatc gctcaattgc tacagttaaa ataatttatc
    20041 acgttatttg tctgattttg tttgattttt gtttaattgg ttagattgat atatgctgat
    20101 agttggcatg ataaataggt ataaagaatg ggaaaccgga caaaagagga tgaactgtac
    20161 cgagaaatgt gcagagttgt cggtaaagtt gtgctggaaa tgcgcgatct ggggcaggaa
    20221 ccaaagcata ttgttatcgc aggcgtatta cgtacagcat tagccaataa acgcattcag
    20281 cgcagtgagc tggaaaagca ggcgatggaa acagtcatta acgcactagt aaaatgacca
    20341 ttcaggatga ggcggtaagc ttcatcctga tattgttagt tcagttgcgg tccagttaat
    20401 c
//
LOCUS       DAPOXO010000090        20394 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPOXO010000090 DAPOXO010000000
VERSION     DAPOXO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20394
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.090"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            19..420
                     /locus_tag="ROH59_003989"
     CDS             19..420
                     /locus_tag="ROH59_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HDX4806412.1"
                     /translation="MTWNPLALATALQTVPEQNIDVTNNESALIIKLNDYGDLQINIL
                     FTSRQMIIETFICPVSSISNPDEFNTFLLRNQKMMPLSSVGISSVQQEEYYIVFGALS
                     LKSSLEDILLEITSLVDNALDLAEITEEYSH"
     gene            439..1137
                     /locus_tag="ROH59_003990"
     CDS             439..1137
                     /locus_tag="ROH59_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
                     /protein_id="HDX4806413.1"
                     /translation="MGILKSLFTLGKSFISQAEESIEETQGVRMLEQHIRDAKAELDK
                     AGKSRVDLLARVKLSHDKLKDLRERKASLEARALEALSKNVNPSLINEVAEEIARLEN
                     LITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKATEAMQRAQQAVTTSTV
                     GASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDEKLAEAGIGGSNKSS
                     AQDVLARLQRQQGE"
     gene            1187..1846
                     /locus_tag="ROH59_003991"
     CDS             1187..1846
                     /locus_tag="ROH59_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HDX4806414.1"
                     /translation="MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLSFRLLEDEL
                     LIALPGEEFTVAAVSHIDLGGGSQIFRYYTSGDEFLQINTTGGEDIDDIDDIKLFVYE
                     ESYGISKESHWREAINAKAMGAMTLNWQEKRWQRFFNSEEPGNIEPVYMLEKVENQNH
                     AKWEVHNFSMGYQRQVTGDTYEYLLLNGEESFNDLGEPEWLFSRALGIDIPLTSLHII
                     G"
     gene            1864..2262
                     /locus_tag="ROH59_003992"
     CDS             1864..2262
                     /locus_tag="ROH59_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HDX4806415.1"
                     /translation="MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNN
                     TAAALAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSE
                     KIINHNTAAGMFMGTAALAGGIFNAACMTW"
     gene            2272..2910
                     /locus_tag="ROH59_003993"
     CDS             2272..2910
                     /locus_tag="ROH59_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HDX4806416.1"
                     /translation="MARKRKSRNNKNIGHGAISRIGRPHNPFEPRRNRYAQKYLTLAL
                     MGGAAFFVLKGCGDSGDVDNDGDGTFYATVQDCIDDGNNSDICAHGWNNAKAAFYADV
                     PKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASR
                     PVWRNTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            2913..4076
                     /locus_tag="ROH59_003994"
     CDS             2913..4076
                     /locus_tag="ROH59_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDX4806417.1"
                     /translation="MLRHNVPVRRDLDRIAADNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWRARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGVIPRDADQYNAIQERLI
                     SRFSELYSREPFYFCCCQDTDEDRSTVLYLQDCAEQAGQESRFIYIEELGLGVGGVLT
                     DLDDNVIQRAFKLYPLEWMMRDDNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFDGEKPQIAAGESYVRKPIYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            4160..5785
                     /locus_tag="ROH59_003995"
     CDS             4160..5785
                     /locus_tag="ROH59_003995"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HDX4806418.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLDDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGIPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     TWCKVMLDTRGGVRLSEQIQNDLLLRATGGVCL"
     gene            complement(5902..6177)
                     /gene="yjfN"
                     /locus_tag="ROH59_003996"
     CDS             complement(5902..6177)
                     /gene="yjfN"
                     /locus_tag="ROH59_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease activator YjfN"
                     /protein_id="HDX4806419.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(6326..6655)
                     /gene="bsmA"
                     /locus_tag="ROH59_003997"
     CDS             complement(6326..6655)
                     /gene="bsmA"
                     /locus_tag="ROH59_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313192.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HDX4806420.1"
                     /translation="MVSRKRNSIIYRFASLLLVLMLSACSALQGTPQPAPPVTDHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIRAKAVAAKADYYVVVMVDETIVTGQWYS
                     QAILYRK"
     gene            6837..7586
                     /gene="yjfP"
                     /locus_tag="ROH59_003998"
     CDS             6837..7586
                     /gene="yjfP"
                     /locus_tag="ROH59_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDX4806421.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCVIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQFWQILLQSMQEFTTLRAAIAEEN
                     WLRDDRLAVGGASMGAMTALGITARHPTVKCTASMMGSGYFTSLARSLFPPLIPETAA
                     QQNEFNNIVAPLAEWEATNHLTELGNRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            complement(7583..8338)
                     /gene="ulaR"
                     /locus_tag="ROH59_003999"
     CDS             complement(7583..8338)
                     /gene="ulaR"
                     /locus_tag="ROH59_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HDX4806422.1"
                     /translation="MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLF
                     SRADQIDMLITGKNANPEILQQLEAQGVSILRV"
     gene            complement(8446..9510)
                     /gene="ulaG"
                     /locus_tag="ROH59_004000"
     CDS             complement(8446..9510)
                     /gene="ulaG"
                     /locus_tag="ROH59_004000"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDX4806423.1"
                     /translation="MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGANVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPG
                     GSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMGEALNAKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            9865..11262
                     /gene="ulaA"
                     /locus_tag="ROH59_004001"
     CDS             9865..11262
                     /gene="ulaA"
                     /locus_tag="ROH59_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDX4806424.1"
                     /translation="MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIERMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
                     CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVNWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFASRAL
                     RAEEDAEKQLAEQSA"
     gene            11278..11583
                     /gene="ulaB"
                     /locus_tag="ROH59_004002"
     CDS             11278..11583
                     /gene="ulaB"
                     /locus_tag="ROH59_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HDX4806425.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            11593..12057
                     /gene="ulaC"
                     /locus_tag="ROH59_004003"
     CDS             11593..12057
                     /gene="ulaC"
                     /locus_tag="ROH59_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HDX4806426.1"
                     /translation="MKLRDSLAENKSIRLQAEAETWQDAVKIGVDLLVAADVVEPRYY
                     QAILDAVEQHGPYFVLAPGLAMPHGRPEEGVKKTGFALVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            12071..12721
                     /gene="ulaD"
                     /locus_tag="ROH59_004004"
     CDS             12071..12721
                     /gene="ulaD"
                     /locus_tag="ROH59_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDX4806427.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIGQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            12731..13585
                     /gene="ulaE"
                     /locus_tag="ROH59_004005"
     CDS             12731..13585
                     /gene="ulaE"
                     /locus_tag="ROH59_004005"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HDX4806428.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETD
                     DRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMT
                     KAGMVEAV"
     gene            13585..14271
                     /gene="ulaF"
                     /locus_tag="ROH59_004006"
     CDS             13585..14271
                     /gene="ulaF"
                     /locus_tag="ROH59_004006"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase UlaF"
                     /protein_id="HDX4806429.1"
                     /translation="MQKLKQQVFEANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKADDMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGDAEPLHTP
                     GIVVYQHGPFVWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(14400..14675)
                     /locus_tag="ROH59_004007"
     CDS             complement(14400..14675)
                     /locus_tag="ROH59_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX4806430.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            15003..15398
                     /gene="rpsF"
                     /locus_tag="ROH59_004008"
     CDS             15003..15398
                     /gene="rpsF"
                     /locus_tag="ROH59_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDX4806431.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            15405..15719
                     /gene="priB"
                     /locus_tag="ROH59_004009"
     CDS             15405..15719
                     /gene="priB"
                     /locus_tag="ROH59_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HDX4806432.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            15724..15951
                     /gene="rpsR"
                     /locus_tag="ROH59_004010"
     CDS             15724..15951
                     /gene="rpsR"
                     /locus_tag="ROH59_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDX4806433.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            15993..16442
                     /gene="rplI"
                     /locus_tag="ROH59_004011"
     CDS             15993..16442
                     /gene="rplI"
                     /locus_tag="ROH59_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDX4806434.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
     gene            16844..17335
                     /locus_tag="ROH59_004012"
     CDS             16844..17335
                     /locus_tag="ROH59_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4806435.1"
                     /translation="MGKKTAPLLPYTNQMLSEFGERLKLARLRRRLTAKQVAERAGMS
                     PITLRSLESGSAGVTIGAYLSVMQVLGLETDLNKLAAEDDLGRQLQDSRLIKKRGLSR
                     VSSKNEEGSQTASLQMRHEKEGHLTTDLTALAEGSTPSITGETSTSLAALLKPIKKPL
                     KGN"
     gene            17338..18605
                     /locus_tag="ROH59_004013"
                     /pseudo
     CDS             17338..18605
                     /locus_tag="ROH59_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606689.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HipA domain-containing protein"
     gene            complement(18748..20025)
                     /locus_tag="ROH59_004014"
     CDS             complement(18748..20025)
                     /locus_tag="ROH59_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806436.1"
                     /translation="MNKIKNYRWHMIALVCFITVINYLDRTALGIAAPTIMETTGITK
                     EQYSWIVSAFQLAYTLGQPIMGFFIDTVGLKLSFAICAAIWGLATMGHALTGTWSGLA
                     FMRALMGFSEASAIPAGVKTASTWFPAKERGVATGVFNMGTSLGAMLAPPLIAWCIMF
                     HSWQFAFIVSGSLALLAALFWFFCYKDPKDAKRLSDEERHYIESGQEQHLKTDKKEKT
                     SIKHILSQRNFWGIGIARFLADPAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLLG
                     DLGCLASGFVAKFFHDRGVSLINSRRITFTIAAVIMMTIGLVSIVENPYIAVLLISIG
                     AFSHQCLSTVAATLGGDLFKKDEVATAVGMAGACAWSGQLIFNLFIGAFVHIIGFAPF
                     FIALAFFDIIGAIALWTLIKVKDEEPQVQLATS"
     gene            complement(20263..>20394)
                     /locus_tag="ROH59_004015"
     CDS             complement(20263..>20394)
                     /locus_tag="ROH59_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDX4806437.1"
                     /translation="IERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ"
BASE COUNT         5068 a         4751 c         5321 g         5254 t
ORIGIN      
        1 atctatatgg aataatatat gacatggaat ccgttggcgc tggcgacggc gctgcaaact
       61 gtacctgaac aaaatattga tgtaacaaat aacgaaagtg cattaattat taaactgaat
      121 gattatggcg atttgcaaat caatattctt tttacttccc gccaaatgat catcgaaacc
      181 tttatttgtc cggtaagtag tatcagcaat ccagatgaat ttaatacctt cttattaaga
      241 aatcagaaga tgatgccgtt gtcatcggta gggatctcca gcgtgcaaca ggaagagtat
      301 tacattgttt tcggtgcgtt atcgcttaaa tcttctcttg aagatatcct gcttgagata
      361 acctcgctgg tagataacgc attggatctg gctgaaatta cagaagaata ttcacactaa
      421 ttacaaggac gggtatttat gggaatttta aaaagtttat ttacgctggg gaaatcgttt
      481 atctcccagg cggaagagtc cattgaagaa acccagggcg tgcgcatgct ggaacagcat
      541 attcgtgacg ctaaagctga actcgataaa gccggaaaat ctcgcgttga tctgctggca
      601 cgggtgaaat taagtcacga taagctgaaa gatttacgtg agcgcaaagc cagtctggaa
      661 gcgcgtgcgc tggaagcgtt aagcaagaac gttaatccgt cgttgattaa cgaagttgct
      721 gaagaaatcg cgcgccttga gaatctcatt accgctgaag agcaagtgtt gtcgaatctg
      781 gaagtctctc gtgatggcgt ggaaaaagca gttacagcga cagcgcagcg tatcgctcag
      841 tttgagcagc aaatggaagt cgttaaagcc actgaagcca tgcagcgtgc acaacaggct
      901 gtaacgacct ctaccgttgg cgcatcttcc agcgtttcga cagcggcaga atccttaaaa
      961 cgcctgcaaa cgcgtcaggc cgaacgtcag gctcgcctgg atgctgccgc acagttggaa
     1021 aaagtcgcgg acggtcgcga tctcgatgaa aagctggcgg aagctggaat tggcggtagc
     1081 aataaaagta gcgcccagga tgtattagca agactgcaac gccaacaggg cgagtaattt
     1141 tttgccagcc tcactgcaag gctggtaact attttaagga taaaatatgt ctggtttttt
     1201 ccagcgtctg tttggcaagg ataataagcc tgctatcgct cgcggtccgc tgggtctgca
     1261 tctcaatagt ggctttacgc tcgacacatt atcgtttcgt ttgctggaag atgaattgct
     1321 gattgcgctg ccgggtgagg aatttacggt agccgctgtc agccacatcg atctgggcgg
     1381 gggtagccag attttccgtt actacacttc gggcgatgag ttcctgcaaa tcaataccac
     1441 tggcggcgaa gatattgatg acattgatga tatcaagctc tttgtctatg aagagagcta
     1501 cggtatcagt aaagagagtc actggcgcga ggcgatcaac gccaaagcga tgggggcaat
     1561 gaccttaaac tggcaggaaa aacgctggca gcgatttttt aacagcgaag aaccgggaaa
     1621 tatcgaaccc gtctacatgc tggaaaaagt agaaaatcaa aaccatgcca aatgggaagt
     1681 gcataatttt agcatgggct accaacggca ggtgaccgga gatacttacg aatatttgct
     1741 gttaaatggt gaggaatctt ttaacgatct cggcgagccg gagtggttat tttcgcgcgc
     1801 gctgggtatc gatatcccgc tgacatcact tcatattatt ggttaattac aaggacgttt
     1861 acaatgcata tactggattc acttcttgct tttagtgcct atttttttat tggcgtggcg
     1921 atggtgatta ttttcctgtt tatctactcc aaaattacac cgcacaacga atggcagtta
     1981 atcaaaaaca ataacaccgc ggcggcactg gcgttcagcg gaacattgtt ggggtacgtg
     2041 atccccttat ccagtgcggc aatcaatgcg gtgagtattc cagactattt cgcatggggc
     2101 gggattgctc tggtgattca attactcgtt tttgctggcg tcaggcttta tatgcccgca
     2161 ttaagcgaaa aaattattaa tcacaatacc gcagccggaa tgtttatggg aaccgccgcg
     2221 ctggctggcg gtatttttaa cgcagcttgt atgacatggt aatggacgat catggccaga
     2281 aaacgcaaat ccagaaataa caaaaatatc ggacatgggg caatcagtcg cattggtaga
     2341 ccgcataatc cttttgagcc gcgccgcaat cgctacgcac aaaaatactt aacgttggcg
     2401 ctaatgggcg gtgccgcttt tttcgtattg aaaggttgtg gcgatagtgg cgatgtcgat
     2461 aacgacggcg acggaacgtt ttacgcgact gtgcaggatt gtattgatga tggtaataat
     2521 tcagatatct gtgctcatgg ctggaacaac gccaaagcgg cattttatgc cgatgttccg
     2581 aagaatatga ctcagcagaa ttgtcagtct aagtatgaaa attgttacta cgacaatgtt
     2641 gaacagagtt ggatcccggt cgtttctgga tttttgttaa gccgggttat tcgtaaagat
     2701 cgcgatgagc cgttcgtcta taacagcggc ggatcctcat ttgcttcccg ccccgtctgg
     2761 cgcaacactt ccggtgatta ctcctggcgc tccggttctg gcaaaaaaga gtcttactct
     2821 tcgggcggct ttaccaccaa aaaagcgtca accgtttctc gcggcggcta tggtcgttct
     2881 tccagcgccc gtgggcattg gggaggctaa tcatgctgag acacaacgtt cctgtgcggc
     2941 gggatctgga ccggattgcc gccgataacg gatttgactt tcatatcatc gacaatgaaa
     3001 tctattggga tgagagtcgg gcttaccgct ttactctgcg ccagattgaa gagcagatcg
     3061 aaaaaccgac tgcggaactg catcagatgt gcctggaggt ggtggatcgt gcggttaaag
     3121 atgaagagat cctgacgcaa ctggcgatcc cgccgttgta ctgggatgtg atcgccgaaa
     3181 gctggcgcgc acgcgatcct tcgttgtatg gccgtatgga ttttgcctgg tgtggtaatg
     3241 caccggttaa gttgctggag tacaacgccg atacgccaac ttcattgtac gagtcggctt
     3301 atttccagtg gttgtggctg gaagatgccc ggcgcagcgg cgttattccg cgcgatgccg
     3361 atcagtacaa tgccattcag gagcgcctga tttcacgctt tagcgagctt tatagccggg
     3421 agccgtttta tttttgctgc tgtcaggata ccgatgaaga caggagtacc gtgctgtact
     3481 tgcaggactg cgccgagcag gcagggcagg agtctcggtt tatctacatt gaagagctcg
     3541 gtttgggcgt cggcggcgta ctgaccgatc ttgatgataa tgtcatccag cgtgcattta
     3601 agctgtatcc gctggagtgg atgatgcgtg acgataacgg tccgctgctg cgcaagcgtc
     3661 gtgagcaatg ggtggagccg ttatggaaaa gtatcttgag taataaaggg ctaatgccgc
     3721 tgctttggcg cttcttccct ggtcatccta accttcttgc atcctggttc gatggtgaaa
     3781 aaccgcagat tgccgctggc gaaagctatg tgcgtaaacc gatttactcg cgcgaaggcg
     3841 gaaacgtcac cattttcgac ggtcagaata acgttgttga ccacgctgat ggtgattacg
     3901 ccgatgaacc gatgatctac caggcgtttc aacctctgcc gcgatttggc gatagctaca
     3961 cactcatcgg tagctggatt gtcgatgatg aagcgtgcgg aatggggatc cgtgaagata
     4021 acacgctgat caccaaagac acctcacgtt tcgttccgca ttacattgct ggataagaat
     4081 gttttagcaa tctctttctg tcatgaatcc atggcagtga ccatactaat ggtgactgcc
     4141 attgatggag ggagacacag tgcactggca aactcacacc gtttttaatc aacctatacc
     4201 attaaataac agcaacttat acctgtctga tggcgcgctt tgcgaagcgg taacgcgtga
     4261 aggtgctggc tgggatagcg attttctcgc cagtattggt cagcagttag gaacggctga
     4321 atcccttgaa ctggggcggc tggcgaatgt gaatccgcct gaattattgc gctacgatgc
     4381 gcaaggacgc cgtctggacg atgtgcgttt tcaccccgcc tggcacctgc tgatgcaggc
     4441 gctatgtacc aatcgggtgc acaatcttgc ctgggaagaa gacgctcgct ccggcgcatt
     4501 tgtggcgcgc gcggcgcgtt ttatgttaca tgcgcaggtt gaggctgggt cgttatgtcc
     4561 gataacgatg acctttgccg ccacgccatt gttgttacag atgttacccg cgccgtttca
     4621 ggactggacc acgccgctgt tgagcgatcg ctacgattct cacttattgc caggtgggca
     4681 aaaacgtggc ttgttgatcg gcatgggaat gacggaaaag cagggcggtt ccgatgtcat
     4741 gagcaacacc acccgcgcag agcgtctgga cgatggttct tatcggctgg tggggcataa
     4801 atggtttttc tcggtgccgc aaagcgatgc gcatctggtg ctggcacaga ccgcgggcgg
     4861 tttgtcctgc ttttttgtgc cgcgcttttt gcctgacggg caacgcaacg cgattcgcct
     4921 cgagcggctg aaagataagc tgggtaatcg ctctaacgcc agctgcgaag tggaatttca
     4981 ggatgccatt ggctggttgt tggggcagga aggggaagga attcgtctga tcctgaaaat
     5041 gggtgggatg acgcgttttg attgcgccct gggtagccat gccatgatgc gccgtgcatt
     5101 ttcgctggcg atttatcatg cacatcaacg ccatgttttt ggtaatccat tgatccaaca
     5161 gccccttatg cgtcatgtct taagtcgcat ggcacttcag cttgaagggc aaacggcgtt
     5221 gctgtttcgt cttgcgcgag cgtgggaccg gcgcgccgat gccaaagaag ctctgtgggc
     5281 gcgtttattt acgcctgcgg cgaaatttgt gatctgcaaa cgtggcattc cgtttgtggc
     5341 cgaagcgatg gaggtgctgg gcggcattgg ttattgcgag gagagcgagc tgccgcggct
     5401 ttaccgggag atgccggtaa acagtatttg ggaaggttcc ggcaatatta tgtgcctgga
     5461 tgtgctgcgc gttctcaata agcaagcggg cgtatacgac ttattgtcgg aagcatttgt
     5521 ggaagtgaaa gggcaggatc gctattttga tcgcgcggtt cgtcgtttac agcagcagct
     5581 gcgtaagcca gctgaagaat tggggcgaga gattactcat cagctattcc tgctgggctg
     5641 cggtgcgcaa atgttgaaat atgcctctcc gccaatggcg cagacgtggt gtaaggtgat
     5701 gttagatacg cgcggcggcg tacggttgtc agagcagatc cagaatgatt tattgctgcg
     5761 ggcgacggga ggagtgtgtt tgtaagcgta tacgactgat gcgacgctgg tttcgatgaa
     5821 ctaaatgaaa tattttaaaa ttgtaggccg gacaaggcgc tcgcgccgca tccggcattg
     5881 ttcatttgct gtagatgaca ctcacgcata cagtatcgcc tgtacgcgcc agttatcagg
     5941 ctgctggtct tcgtacatgg taataatgcg gtaccatgac gcaccttgtt catcggcctt
     6001 taacgccacg atacgttcca cgtcctgcgg atcccctgaa atattgctaa ctgagatctg
     6061 acctatttca ttcaggcccg tcacgcagtc agcactggcg aattctgcag actgtgccgt
     6121 ggcgctcgca ggataagtca ctaattgcag cgagggtgag gcaagtaatt gtttcatcgt
     6181 cagctccatt tttcgtttcc ccacatgttg cagggcattc catcgcggta ataaacgccc
     6241 gagcttccag ccggtaattt attgtgcaca ggtaaacgca tagggacgca aagcaatgta
     6301 aagctgacta tgttagttgt ctgatttatt tacggtacaa aatggcttgt gaataccact
     6361 gtcctgtcac gatggtttcg tccaccatga cgacaacgta ataatcagct tttgcagcga
     6421 cagctttcgc tctgatttct gctaatgcgt catccggaga acctcgaacc atcgtgctta
     6481 cgctacctat tcgctgtaac ccttgcgtct ggtcacggcg aatctcttgc ggatggtccg
     6541 ttactggcgg tgctggctgt ggcgtacctt gcagtgcgct acaggcactt aacatcaaca
     6601 ccaataataa actggcaaac cggtaaataa tgctattacg tttcctgcta accatagtgt
     6661 agtgccttat taatttaact ttgggggaat gttcccgaat tgttacctgg tacgcgattt
     6721 tcgaatgaaa acgtgacgaa agcgtaaccc acatctcaac attatgaact aataccgcca
     6781 gcagaaactt gtgctaagga tttcttcatg tcataccaga caaaaaggag agacagatga
     6841 ttgaaataga atcacgcgag ctggcagata ttcccgttct tcatgcttat cctgtcgggc
     6901 aaaaagatac cccgttaccg tgtgtgattt tttatcacgg ctttacttcg tccagtctgg
     6961 tgtatagcta ttttgccgtt gcgctggcgc aggctggttt gcgggtgatc atgccggatg
     7021 cgcccgatca cggtagccgt tttagtggcg acgcagcgcg gcggttaaat caattctggc
     7081 aaatcttgct acaaagtatg caggaattca ctaccttacg tgcggcaata gccgaagaaa
     7141 actggctgcg tgatgaccgt ctggcagtcg gtggcgcgtc gatgggcgcg atgacggcac
     7201 tgggaattac cgctcgccac cccacggtaa aatgtaccgc cagcatgatg ggatcgggct
     7261 attttacatc gctcgcccgt tcactgtttc caccgctgat acctgaaacg gcagcacagc
     7321 agaatgaatt caataacatt gtcgcgccgc tggcagagtg ggaagcgaca aaccatctga
     7381 cagagttggg gaacagaccg ctgctcttat ggcatggcct tgacgatgac gtcgtgcctg
     7441 ccgacgaatc actacgtttg cagcaggcct taagcgagac gggacgggat aaactgctaa
     7501 cctgttcatg gcagccaggc gtgcgtcacc gcattacgcc tgaggcgtta gatgctgccg
     7561 tgacattttt ccgccagcat ctttaaacac gcagaatgct gaccccttgc gcttccagtt
     7621 gttgcaggat ttccgggtta gcatttttgc cggtgatcag catatcgatt tgatcggcac
     7681 ggctaaaaag cattcccgcg cgttcgccaa tcttactgct atcaaccagt accaccagtt
     7741 tccctaccac gctcagcatc ttctgctctg ccattgccgt cagcatatcg gttttataca
     7801 acccttctgc tgtcagtcct ttgccgctgg taaacatcca gtgcccggca tagagactgt
     7861 tttcgctgcc ttgcgggctt aaagtgatgg actgactttt gttgtactgt ccgcccataa
     7921 tgatcacgct gtcatgctcc tgatcgatca ggtaatttgc cagcggtaga taattagtga
     7981 tgatttgcac tggcttgcca cacatttccc gcccaagcag aaacgcggtg gagccgcagt
     8041 tgatgactac gctttcgccc ggattaacca gctgcgaggc cgctttagca atacgtactt
     8101 tttcatcgtg attctgcgct tgatgcagat tcatcggcgt ccagcgcggg cgctgttggg
     8161 taatagcttc tgcgccattg cgcacttttt tcagtttgcc gctttcgtca agtttattga
     8221 tatcgcgtcg tgcagtggca ggcgaaattc ccagacgctc aacgactttc tcaacggtca
     8281 caaagcccaa ttgtgcgagc atttccagga ggatttgatg tctttgtgct tcagtcatga
     8341 gctattccga taaaatttga tttttttaga tgatatttga aatagccagg aaatactatg
     8401 ccggatagcg cgagcatctc cacgctatcc ggtacaagcg acagattaca ggaacgactt
     8461 gaacggcaga tctggttcaa tagtgaagca atcatcgaaa ccacgcggat agtggtactc
     8521 gaagttgtct ttatccagcg gccaggtaaa tttgccgccg acctgccaga taaacggctt
     8581 gaagccatac ttcaggcgat cttttttcat ctcccacagc acgcggatct cttgcggatc
     8641 ggcctggaag tttgaccaga tatcgtggtg gaacgggatc actactttcg cattcagcgc
     8701 ttcgcccata cgcaggatat cagcactggt cattttgtcg gtgataccac gtgggttctc
     8761 tccgtacgat cctaaagcca cgtcgatctg atgctcgtta ccatgttttg cataatagtt
     8821 ggagtagtgg gaatcgccgc tgtgatacag ggaaccgccc ggcgttttga acaggtagtt
     8881 taccgcgcga tcgtccatgc cgtccggcag tacgccagcc gctttttgat cggctggcag
     8941 cgtgatcagt gccgtgcggt cgaaagcatc aagtgcatga atttcaatgt cttttacctt
     9001 cactacgtcg cccggtttaa cgacgatgca acgctctttc ggtacgcccc agccaatcca
     9061 caaatcaacg caggttttcg gtccaatgaa cggtacgtca tcagcacagt tctgcatcac
     9121 ggcagcagcg acgttaacgt cgatatgatc gttgtgatcg tgagtcgcca gtaccgcgtc
     9181 gatctggcga atcgcaaacg gatcaagaac aaacggggtg gtgcgcaggt ttggctgcag
     9241 ttttttcacg ccagccatgc gctgcatctg gtgaccctgt ttcattaacg ggttaccgtg
     9301 gctttgtttg ccagtaccgc accaaaaatc aacacaaacg ttggcaccgc cttctgattt
     9361 caaccagatt ccggtacagc cgagccacca cattgcgaaa gtgcctggtg cgacctgctc
     9421 ttgctcaatt tcttcattca gccagctacc ccactccggg aaagtgctca ggatccagga
     9481 ctcacgggtg atacttttca ctttactcat cgccatttac cttcgtgata gttcaattcg
     9541 aatcaatatg tgattggttt tgattaatcc tgacactatt ttttcaggaa ggcaatgacc
     9601 attttttgac tttttagcag gagagttatt gtggattttg agtgtagaaa gattaaattg
     9661 aatgtgtaat gcaattaact aaatgaattt aaatgaataa atatttcatt ccgtgaatcc
     9721 cattctgttt atgtggaatt atttgcgtgc gacgtcacat ttaatcataa ataatcttgt
     9781 tgtgattact tttgaaaatt agagtgagag cacaacattc cgggtgtgcg aaatacccgg
     9841 ttacctcttc ttcaggagat cgttatggag atcctctaca acatctttac cgtgtttttt
     9901 aaccaggtca tgaccaatgc cccgttgttg ctgggtattg tgacctgtct gggttacatc
     9961 ctactgcgca aaagtgtcag cgttattatt aaaggtacga ttaaaaccat aattggtttc
    10021 atgttgttgc aggcagggtc cggcatcctg accagcacct tcaaaccggt ggtggcgaaa
    10081 atgtccgaag tctacggcat taacggcgca atttccgata cttacgcgtc gatgatggca
    10141 accattgaac gcatgggcga tgcctatagc tgggtgggtt acgcggtgtt gttagcgctg
    10201 gcgctgaaca tctgttacgt gctgctgcgt cgcattaccg gtattcgaac catcatgctg
    10261 actggtcaca tcatgttcca gcaggcgggg ctgattgccg ttacgctgtt tatcttcggc
    10321 tactccatgt ggacgaccat tatctgcacc gcgattctgg tttcgctcta ctggggcatt
    10381 acctccaaca tgatgtacaa gccgacacag gaagtcaccg acggctgtgg tttctccatt
    10441 ggtcaccagc agcagttcgc atcatggatt gcttataaag tcgcaccgtt ccttggcaaa
    10501 aaagaggaaa gcgttgaaga cctcaaactg cctggctggc tgaatatttt ccacgacaac
    10561 atcgtctcca cggcgattgt catgactatc ttctttggtg ccattctgct ctcctttggt
    10621 atcgacaccg tgcaggcgat ggcaggcaaa gtgaactgga cggtgtacat cctgcaaacc
    10681 ggtttctcct ttgcggtggc gatcttcatc atcactcagg gcgtgcgcat gtttgtggcg
    10741 gaactctctg aagcatttaa cggtatctcc cagcgtctga tcccaggtgc ggttctggcg
    10801 attgactgtg cggctattta tagcttcgcg ccgaacgccg tggtctgggg ttttatgtgg
    10861 ggcaccatcg ggcaactgat tgcggttggt atcctggtcg cctgtggctc ttcaatcctg
    10921 attattcccg gctttatccc gatgttcttc tccaacgcca ctatcggcgt gttcgctaac
    10981 cacttcggcg gctggcgtgc ggcgctgaaa atttgtctgg tgatggggat gatcgaaatc
    11041 tttggttgcg tctgggcagt gaaactcacc ggtatgagtg cctggatggg tatggcggac
    11101 tggtcgattc tggcaccgcc gatgatgcag ggcttcttct ccatcggtat cgcctttatg
    11161 gccgtcatca ttgtaattgc actggcttat atgttcttcg ctagccgcgc gctgcgcgca
    11221 gaagaagatg cagaaaaaca actggcagaa caatctgctt aataaggagt tttgattatg
    11281 accgttcgta ttctggctgt gtgtggtaac ggacaaggca gttccatgat catgaaaatg
    11341 aaagtggacc agtttttaac ccagtcgaac attgaccaca cggtaaacag ctgcgcggtt
    11401 ggcgaataca aaagcgagtt gagcggcgcg gatatcatca tcgcttctac ccatattgcg
    11461 ggcgaaatca ccgtgaccgg caacaaatat gtggttggcg tgcgcaacat gctctctcct
    11521 gctgattttg gcccgaaact gctggaagtg atcaaagagc atttcccgca ggacgtgaag
    11581 taaggacgcg ccatgaaatt acgtgattcg ctggctgaaa ataaatctat ccgcctgcaa
    11641 gcggaagcag agacatggca ggacgcagtg aaaatcggcg ttgatctgct ggtagcggca
    11701 gatgtggtag agccgcgtta ctaccaggcg attctggatg cggttgaaca gcacggcccg
    11761 tactttgtgc tcgcccccgg cctggcaatg ccgcacggac gcccggaaga gggcgttaag
    11821 aaaaccggtt ttgcgctggt gacgctgaaa aagccgctgg agttcaacca cgaagataac
    11881 gatccggtgg atatcctcat caccatggcg gcggttgatg ccaacactca ccaggaagtg
    11941 ggcatcatgc agatcgtcaa cctgtttgaa gatgaagaga atttcgaccg tttacgtgcc
    12001 tgccgtaccg agcaggaagt actggatctc attgaccgca ccaacgcggc agcttaagaa
    12061 ggaattgaac atgtcattac cgatgttgca agtcgcgctg gacaaccaga ctatggatag
    12121 cgcctacgaa accactcgcc tgattgccga agaagtcgac attatcgaag tgggcaccat
    12181 tctttgcgta ggcgaaggcg tgcgtgcggt tcgtgacctg aaagcgctgt acccgcacaa
    12241 aatcgtactg gctgacgcca aaattgccga tgcaggcaaa atcctttctc gcatgtgctt
    12301 cgaagccaac gctgactggg tgaccgtaat ttgttgtgcg gatatcaaca ccgccaaagg
    12361 cgcgctggac gtggcaaaag agtttaatgg cgacgtgcag atcgaactga ccggctactg
    12421 gacctgggaa caggcgcagc agtggcgcga cgcaggcatt gggcaggtgg tttatcaccg
    12481 cagccgtgac gcgcaggccg caggcgtggc gtggggcgaa gcggacatta ccgcgatcaa
    12541 acgtctttcc gatatgggct tcaaagtcac cgtcaccggt ggtctggcgc tggaagatct
    12601 gccgttgttt aaaggcattc cgattcatgt gtttatcgct ggtcgcagca tccgtgatgc
    12661 agcctctccg gttgaagccg cgcgtcagtt caaacgttcc atcgccgaac tgtggggcta
    12721 aggagcggat atgttgtcca aacaaatccc gcttggcatc tacgaaaaag cgctccccgc
    12781 tggggagtgc tggctggaac gactgcaact ggcaaaaacg ttaggcttcg attttgtcga
    12841 gatgtcagta gatgaaacgg acgatcgcct ttcgcgcctc gactggagcc gcgagcagcg
    12901 tctggcactg gtgaacgcga ttgttgaaac cggcgtgcgc gtaccgtcca tgtgcctttc
    12961 tgctcatcgt cgtttcccgc tgggaagcga agatgacgcg gtgcgggcgc aggggctgga
    13021 gattatgcgt aaagctatcc agttcgccca ggacgtcggc attcgcgtga tccaactggc
    13081 gggctatgac gtttactatc aggaagccaa taacgaaacg cgtcgtcgtt ttcgtgacgg
    13141 cctgaaagag agcgttgaga tggcaagccg cgcgcaggtc acgctggcga tggagatcat
    13201 ggattaccca ttgatgaact ccatcagcaa ggcgctgggc tacgcacact atctcaacaa
    13261 tccgtggttc cagctctacc cggatatcgg caacctgtcg gcgtgggaca acgacgtgca
    13321 gatggagttg caggccggaa tcgggcatat cgtcgcggta catgtgaaag acaccaaacc
    13381 aggcgtcttc aaaaacgtgc cttttggcga aggtgttgtg gattttgaac gttgcttcga
    13441 aacgctcaaa cagagtggct attgcgggcc gtacctgatt gagatgtgga gcgaaacggc
    13501 ggaagatccg gcggcagaag tggcgaaagc gcgcgattgg gtgaaagcgc gcatgaccaa
    13561 agcaggcatg gtggaggcgg tataatgcaa aagctgaaac agcaggtgtt tgaggccaac
    13621 atggatctgc cgcgttacgg gctggtgacc tttacctggg gcaacgtcag cgccattgac
    13681 cgcgaacgcg ggctggtggt gatcaagccc agcggcgtcg cctacgaaac catgaaagca
    13741 gacgatatgg tggtggtcga tatgagcggt aaggtggtgg aaggggagta tcgtccgtct
    13801 tccgacactg cgacgcatct cgaactctac cgtcgttatc cgtcgcttgg tggtattgtc
    13861 catacccact ccactcatgc caccgcatgg gcgcaggcgg ggctggcgat cccggcgtta
    13921 ggcaccacgc acgccgatta cttctttggc gacatcccgt gcacgcgcgg attaagcgaa
    13981 gaagaggtgc agggtgagta cgaactgaat accggcaaag tgattatcga aacgctgggt
    14041 gacgccgagc cgctgcatac gccgggaatt gtggtgtatc agcacggacc gttcgtctgg
    14101 gggaaagatg cccacgatgc ggtgcataac gcggtggtga tggaagaagt ggcgaaaatg
    14161 gcgtggattg cgcgcagtat taacccacaa ctgaatcaca tcgacagctt tctgatgaat
    14221 aaacacttca tgcgtaagca cggtcccaac gcctattacg ggcagaagta aaacacgcgc
    14281 tgcggaaatt tccttcttcg ggagataact ggtctaattc cgcagccgtt tttcaaaaaa
    14341 agccccctgc gaagggggca aagcaaacta tggcaatgtt tcgttggtta tacctggtgc
    14401 tagcgataaa tatccgcgct ggcgtgcata ttgccgttac tccccggttc ccgcatcaga
    14461 atcacatggt agtacgttgc gccttgcgca tctgtctctt catttaatgc ctgacgtgct
    14521 tcactttcag tggcgaagtt atggttgata taaatcacac ctaagctttg cacatcatcc
    14581 atatttctgg cctggtggtt attaatttca atggctgccc atgtatttgc acttagcaaa
    14641 agcacagcca gaagggctaa aacacgactg aacatagata cctcctcgac ggctgacttt
    14701 gtgtgctctc ctcttgtggt gatcttctga tttaatttta atcaatgata aagaagttga
    14761 tggtgaccat ttctgatgca gttgttcaaa aaaacaccat gacgaagtgt gatgaactcc
    14821 aaatcagcga tttagaggtt atttgcgaaa ggggcgattt atttctgctc agcccttgag
    14881 tttagcgggg tatgtcagta ctataacgcg tcatttttca gccgaccttt aacacgttcc
    14941 ttgcctcccc gggattcggc tgacccagac aggaggctga ataatccgta aggagcaatt
    15001 cgatgcgtca ttacgaaatc gtttttatgg tccatcctga ccagagcgaa caggttccgg
    15061 gcatgatcga gcgctacact gctgccatca ctggtgcaga aggcaagatc caccgtctgg
    15121 aagactgggg ccgccgtcag ctggcttacc cgatcaacaa actgcacaaa gcacactacg
    15181 ttctgatgaa cgttgaagct ccgcaggaag tgatcgatga gctggaaact accttccgct
    15241 tcaacgatgc cgttatccgc agcatggtta tgcgtaccaa gcacgctgtt accgaagcat
    15301 ctccgatggt taaagcgaaa gacgagcgcc gtgagcgtcg cgatgatttc gcaaacgaaa
    15361 ccgctgatga tgctgaagct ggggattctg aagagtaatt tctgatgacc aaccgtctgg
    15421 tgttgtccgg caccgtgtgc aggactcccc ttcgaaaggt cagtccatca ggaattcctc
    15481 actgccagtt cgtgcttgag catcgttctg tgcaggagga agccggcttt caccggcagg
    15541 cgtggtgcca aatgcccgtt attgttagcg gacacgaaaa ccaggccatt actcacagta
    15601 taacggtcgg cagtcgcata accgttcagg ggttcatttc atgccataag gcaaagaacg
    15661 gactgagcaa aatggttttg catgccgagc agattgaatt gatagattct ggagactagc
    15721 catatggcac gttatttccg tcgtcgcaag ttctgccgtt tcaccgcgga aggcgttcaa
    15781 gagatcgact ataaagatat cgctacgctg aaaaactaca tcaccgaaag cggtaagatt
    15841 gtcccaagcc gtatcaccgg tacccgtgca aaataccagc gtcagctggc tcgcgctatc
    15901 aaacgcgctc gctacctgtc cctgctgccg tacactgatc gccatcagta atcggtcacg
    15961 gtccattaat acgactttga gaggataagg taatgcaagt tattctgctt gataaagtag
    16021 caaacctggg tagcctgggt gatcaggtaa acgttaaagc gggctatgct cgtaacttcc
    16081 tggtaccgca gggtaaagct gttccagcta ccaagaaaaa cattgaattc ttcgaagcac
    16141 gtcgcgctga actggaagct aaactggctg aagttctggc agcagctaat gctcgcgctg
    16201 agaaaatcaa tgcactggaa actgttacca tcgcgtctaa agctggcgac gaaggtaaac
    16261 tgttcggttc catcggtact cgcgacatcg ctgacgctgt aactgcagct ggcgttgaag
    16321 tggctaagag cgaagttcgt ctgccgaacg gcgttctgcg taccactggt gaacacgaag
    16381 tgagcttcca ggttcacagc gaagtattcg cgaaagtgat cgtaaacgta gtagctgaat
    16441 aattcgttat tcaacgagac gtaaaaacgc cgaccagtgg tcggcgtttt gcttttaagt
    16501 gataaaaacc gcagaaacag acgttccctc cataaatctc ttgctattcc ttttataaaa
    16561 agttcgcagt acccatacct ggcccccagc ctcgccgctg gtagttcgtg tcatgttttt
    16621 tacgcgtaaa acacgacaaa agcatcaata cagcgatcgt ctcacttgta tgataataaa
    16681 aacaatatgt tatatatgaa tgtgctgtta ttttattgtt tttatatata aaaagataaa
    16741 atatcatcac tttcgtaatc ttgaacgctt tgcaggtgcg ttcaatccaa taaatgctaa
    16801 tattatggct atcatagcca taaaaagata aaatattatc actatgggta aaaaaacagc
    16861 accgttactc ccttatacga atcagatgct tagtgaattt ggtgagcggc tgaaacttgc
    16921 tcgtttacga cgcaggctta ccgcaaagca agttgctgaa cgtgctggga tgtcgccaat
    16981 aacattgcgc tctctggagt caggaagtgc aggggtcacg ataggggcat atttgtctgt
    17041 gatgcaggtt ttgggcctgg aaacggattt aaataagctt gcagctgaag acgacttagg
    17101 gcgtcagctc caggattccc gtttgattaa aaaaagaggg ctgtctcgtg tatcaagtaa
    17161 gaatgaagaa ggttctcaga cagcctcatt gcagatgagg cacgagaaag aaggtcatct
    17221 caccacggat ttaacagcac tggcagaagg ctcgacgcca tctattacag gagaaacatc
    17281 aacctctctt gctgcactat taaaaccgat aaaaaaaccg ttaaaaggaa attaattatg
    17341 gcattaatcg gagtgtatgc ggattgggaa ggcctggatg gtcctgcgcg tattggttat
    17401 ttacacagtc gtcgcactcg ggcgcgtgag atatttgagt ttgagtacga taaaaaggcg
    17461 cttgcagatc cttcacttaa tttcattcag ttagatcctg aaataatgtt gtatgaggga
    17521 gcacagtacc caattcctcc aaaggataaa tttggtgcat ttagtgattc ctgcccggat
    17581 cgttgggggc gtatgctaat gaagcgtcgt tttgagaggg atattcgaga cgggttatgt
    17641 gataaagact cccaccttta tgagtctgat tatctactag gtgttcatga tctttatcgg
    17701 gttggggctc ttcgatacaa acgtgaagac gctggagagt ttcttgataa tcgcattgat
    17761 gttgcagccc caccatttac cgaaatagcg agtctggaaa gggttagccg ggcaattgaa
    17821 gaagatcctg ataataaaga gtaatggggc aaaaatggtt aagaatgcta atcgctccgg
    17881 ggggatcatt agggggggca cgtccgaaag ccagtgttgt tgatgaagct gggcatctct
    17941 acatcgctaa atttcccagt gtaaaagatg agtatgatgt tggtggatgg gaaatggtcg
    18001 ttaatgcact tgctgttggc tgtggactga atgttgcacc tgctcaggcg cataaatttg
    18061 ccagcaatta ccattgtttt atggttcgtc gttttgaccg cactaatgcg ggaaggcgtc
    18121 tgcattttgc ttcggctatg acactaacca ggcatcagga tggtgaagat gcctctacag
    18181 gtgtgagtta tctggaatta gcagatgttc ttatcagaca tggcgcgcag actaatactg
    18241 accttaagga actctggtcc aggattgttt ttaatattct tgttactaat accgatgatc
    18301 atttacgcaa tcatggattt atcttgatac caggaaaagg ttggcggctt tctgaggcat
    18361 atgatttgaa tcctgtggtc aggtctgatg gtctaaaact caatattacg gaaaatgaca
    18421 atgcacttga tttggaatta gctagagaag ttgcagagta ttttcgactt agtttgacgg
    18481 aagctgatga cattattgct aattttagag ggattgtcag tcagtggcga atcattgccg
    18541 agcgtcttcg attacctggt cgtgagcaag agttaatggc agaggcgttc aggggggcaa
    18601 tttagaatag ttatttcgat atattcgcta aatcataaat ttgcgaagca atgccagtag
    18661 atactgaacg ttttggaaga gacgtttaat ttatgagaaa aatagaaacg ctacaaagct
    18721 aaattatagc gtttctatgt aaaataatta gcttgtcgct aactgtactt gtggttcttc
    18781 gtctttaact ttgataagcg tccacagcgc aatggcgcca ataatgtcaa agaaagccag
    18841 ggcaataaag aacggcgcga agccgataat gtgaacgaat gccccgataa acaggttgaa
    18901 aatcaactga ccgctccatg cacaggctcc tgccataccc acagcggtag ctacttcgtc
    18961 ttttttgaat aggtcaccgc ccagagttgc tgcaacagta gaaagacatt gatgcgagaa
    19021 tgcgccaatg ctaatcagta atacggcgat gtagggattt tcgacaatac tcaccagacc
    19081 aatcgtcatc ataatgacgg ctgcaatagt gaaggtaatt cttcgtgagt taattaaact
    19141 cacgccgcga tcgtggaaga acttcgcgac aaaaccactg gctaaacagc cgagatcgcc
    19201 cagcaggaaa ggtagccaga cgaacatggc aatttctttc aggctaaaat gcagcgtttc
    19261 gacgaagaaa atcggtaccc agaagttaat ggttccccat gccgggtcag cgagaaaacg
    19321 cgcgatgcca atcccccaga aattacgttg gctgaggata tgcttgattg acgttttttc
    19381 tttcttatct gttttaagat gctgttcttg cccagactca atatagtggc gctcttcatc
    19441 agaaaggcgt ttagcatctt ttggatcttt ataacaaaag aaccaaaata aagccgcgag
    19501 taaagcaagg ctacctgaga caataaacgc aaattgccag ctatgaaaca taatgcacca
    19561 ggcaatcaac ggtggagcaa gcatcgcgcc gagtgaggtg cccatattga aaacacctgt
    19621 cgccacgcca cgctcttttg ccgggaacca tgttgatgcg gtttttacac ccgcaggaat
    19681 tgccgatgct tcgctgaaac ccatcagggc gcgcataaat gccagacctg accatgttcc
    19741 tgtcaaggca tgccccattg tcgccaggcc ccagattgcg gcacatatcg caaaacttaa
    19801 cttcagaccc acggtatcaa taaagaagcc cattatcggt tgccccaatg tataggccaa
    19861 ctggaatgca ctgacaatcc atgaatattg ttctttggtt attccggttg tctccataat
    19921 cgttggagcc gcaataccta acgccgttct gtccagataa ttgattacag tgataaagca
    19981 tacgagggca atcatatgcc atcgataatt ctttatttta ttcattttta aaccttttaa
    20041 ttatattaat aaaccctggt tgttggtatt tccatgtaat aggcaataaa aatcaggtac
    20101 agaggaaata ttggaaatta ttgtgtgtaa atgtctccct ttaaaaagtc tggccagttt
    20161 ttttcaaagt aaataccgtt aatacacggt tgcatacgta aagactttac ttcggtaata
    20221 aaagaacctt gcgaatattg aattgttggt aatgactcca acttactgat agtgttttat
    20281 gttcagataa tgcccgatga ctttgtcatg cagctccacc gattttgaga acgacagtga
    20341 cttccgtccc agccttgcca gatgttgtct cagattcagg ttatgtcgct caat
//
LOCUS       DAPOXO010000091        20174 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPOXO010000091 DAPOXO010000000
VERSION     DAPOXO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20174
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.091"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..164
                     /locus_tag="ROH59_004016"
     CDS             <1..164
                     /locus_tag="ROH59_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX4806438.1"
                     /translation="TRQGYAIEAITATIDWIKENGFSLIKAGVNPENTLSKKLLIRIG
                     FNFSSIEDG"
     gene            541..798
                     /locus_tag="ROH59_004017"
     CDS             541..798
                     /locus_tag="ROH59_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjhX family toxin"
                     /protein_id="HDX4806439.1"
                     /translation="MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLT
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQLDNR"
     gene            810..1361
                     /locus_tag="ROH59_004018"
     CDS             810..1361
                     /locus_tag="ROH59_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX4806440.1"
                     /translation="MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDES
                     ARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMHILAPLAVIPEYQGMGVGGRLIR
                     TGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
                     QPMNVTGHIQCAQALMKPEHWRE"
     gene            1413..2159
                     /locus_tag="ROH59_004019"
     CDS             1413..2159
                     /locus_tag="ROH59_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDX4806441.1"
                     /translation="MDIPRIFTISESEHRIHNPFTEEKYATLGRVLRMKPETRILDLG
                     SGSGEMLCTWARDHGITGTGIDMSSLFTAQARRRAEELGVSERVHFIHNDAAGYVANE
                     KCDVAACVGATWIAGGFAGTVELLAQSLKPGGIMLIGEPYWRQLPATDEIAQACGVSS
                     TTDFLTLPGLVSAFDDLGYDVVEMVLADQEGWDRYEAAKWLTMRRWLEANPDDDFAAE
                     VRAELNISPKRHVTYAREYFGWGVFALIAR"
     gene            2287..2547
                     /locus_tag="ROH59_004020"
     CDS             2287..2547
                     /locus_tag="ROH59_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806442.1"
                     /translation="MSQHEQFCQACGMPMSAPDAHSASDQYCAYCSDSNGNLKPWEEA
                     VSGLASFLDSWQKVGPEEAHKRAKRYLTAMPAWAHKAESDLS"
     gene            2585..2701
                     /locus_tag="ROH59_004021"
                     /pseudo
     CDS             2585..2701
                     /locus_tag="ROH59_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227376.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            2946..4067
                     /locus_tag="ROH59_004022"
     CDS             2946..4067
                     /locus_tag="ROH59_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418725.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDX4806443.1"
                     /translation="MSFSVQETLFSLLQHNAISGHENAVADVMLCEFRRQAKEVWRDR
                     LGNVVARYGSDKPDALRLMIFAHMDEVGFMVRKIEPSGFLRFERVGGPAQVTMAGSIV
                     TLTGDKGPVMGCIGIKSYHFAKGDERTQSPSVDKLWIDIGAKDKDDAIRMGIQVGTPV
                     TLYNPPQLLANDLVCSKALDDRLGCTALLGVADAISTTELDIAVYLVASVQEEFNIRG
                     IVPVLRRVKPDLAIGIDITPSCDTPDLHDYSEVRINQGVGITCLNYHGRGTLAGLITP
                     PRLIRMLEQTALEHNIPVQREVAPGVITETGYIQVEQDGIPCASLSIPCRYTHSPAEV
                     ASLRDLTDCIRLLTALAGMSAAHFPVEPDSGTTQEAHPL"
     gene            4064..4342
                     /locus_tag="ROH59_004023"
     CDS             4064..4342
                     /locus_tag="ROH59_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDX4806444.1"
                     /translation="MKKILVACGTGMSTSTMIAHKLQEFLTEQGISATTAQCCLNEIP
                     LNCNGMDLIVTSMRTNSDYGIPTLNGAALLTGINDDALKQQIKALLTQ"
     gene            4354..5667
                     /locus_tag="ROH59_004024"
     CDS             4354..5667
                     /locus_tag="ROH59_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDX4806445.1"
                     /translation="MFDYILSLGGTVFVPIIMIVIGLIFRIPWLQAIKAGVTVGIGFV
                     GMGLVIVMAIDSLSPPIKVMIERFGLALHVFDVGAGPASGVGYATAIGAMIIPVIFLL
                     NVAMLVTRLTKTMNVDIYNYWHYAITGTVVQLMTGSLIYGVLGAICHAALSLKMADWT
                     AKRVQNIVGLEGISIPQGYGSSSVPLFVLLDAIYEKIPFMKGRNIDAQEIQKRYGMVG
                     DPVIIGVVLGLIFGLAAGEGFKGCASLMITVAAIMVLFPRMIRLIVEGLMPISDGARK
                     FFQKYFKGREVYIGLDTAVTLGHPTTIAVGLLLIPIMLILASILPGNKVLPLADLPVA
                     PFFICMATVIHRGDLVRTLISGVIVMITVLLIATQFAPYFTEMALKGGFSFAGESAQI
                     SALSVGNMFGWSISELMSLGIIGVVVAVGIVASVVLFLRKRELSE"
     gene            5680..6486
                     /gene="sgcQ"
                     /locus_tag="ROH59_004025"
     CDS             5680..6486
                     /gene="sgcQ"
                     /locus_tag="ROH59_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA family protein SgcQ"
                     /protein_id="HDX4806446.1"
                     /translation="MSWLKEVIGTEKAVIAMCHLRALPGDPSFDAQLGMNWVIDKAWD
                     DLMALQNGGVDAVMFSNEFSLPYLTKVRPETTAAMARIIGQLMSDIRIPFGVNVLWDP
                     VASFDLAMATGAKFIREIFTGAYASDFGVWDTNVGETIRHQHRIGAGEVKTLFNIVPE
                     AAVYLGNRDICSIAKSTVFNNHPDALCVSGLTAGTRTDSALLKRVKETVPDTVVLANT
                     GVCLENVEEQLSIADGCVTATTFKKDGVFANFVDQARVSQFMEKVHHIRR"
     gene            6617..7048
                     /locus_tag="ROH59_004026"
     CDS             6617..7048
                     /locus_tag="ROH59_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX4806447.1"
                     /translation="MINDIKWVQAQREATDWRQAVEIATRPLVAYGAAQPCYVNGIIE
                     NTLNWGPYYLIAPGIALPHARPEQGANYNQVSITTLRTPVAFGNEECDPVWLLLCVSA
                     TDANAHILTIQRISQFIDSPQRLAAVGNASTDDALFALVSG"
     gene            7060..7692
                     /locus_tag="ROH59_004027"
     CDS             7060..7692
                     /locus_tag="ROH59_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3 epimerase family protein"
                     /protein_id="HDX4806448.1"
                     /translation="MILHPSLASANPLHYGRELTALDNLDFGSLHLDIEDSSFINNIT
                     FGMKTVQAVARQTPHPLSFHFMVARPQRWFNALAEIRPAWIFVHAETLDYPSETLTEI
                     RHTGARAGLVFNPATPIDAWRYLASELDGVMVMTSEPDGQGQRFIPSMCEKIQKVRTA
                     FPQTECWADGGITLAAAQQLAAAGAQHMVIGRALFSSSDYRATLAQFATL"
     gene            7709..8491
                     /locus_tag="ROH59_004028"
     CDS             7709..8491
                     /locus_tag="ROH59_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4806449.1"
                     /translation="MSQQRPDRIKQMLHYLWQHRHLSTQQAMELFGYAEATVRRDFQY
                     IANQYPGMIRGHGCLDFDDSTDDKEYVFDVKRTLQSVAKREIAALARTMIKDGDCFFL
                     DSGSTCLELAKCLADARVKVICNDIKIANELGCFPHVESYIIGGLIRPGYFSVGESLA
                     LEMINAFSVERAFISCDALSLETGITNATMFEVGVKTRIIQRSREVILMADHSKFDAV
                     EPHAVATLSCIKTIISDSGLPETIAQRYQRAGCQLFLPHSIK"
     gene            8794..9582
                     /locus_tag="ROH59_004029"
     CDS             8794..9582
                     /locus_tag="ROH59_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDX4806450.1"
                     /translation="MVRKGCNSLVRAEKILTHIAWVGMASYMELLNKFQYPKSSLLNL
                     LNVMVECGFLIKNKNGYYSLGIKNYELGCQALHRQNIFEVTKRPMQELSLKSGLVCHL
                     GAMESISAIYLDKIESPDSVPTSKSWIGKKIELHITALGKALLAWKTREELDYFLEAL
                     TLTPHTRNTFTDKKLFLEELQKTRLRGWAIDNEESTYGAVCLSMPVFNMYNRVNYAIS
                     LSGDPVVYSGNKIDSYLELLRKCAEQISYGLGYRNENEHLRKGN"
     gene            9587..10492
                     /locus_tag="ROH59_004030"
     CDS             9587..10492
                     /locus_tag="ROH59_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418718.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDX4806451.1"
                     /translation="MKKFSGIIPPVSSTFHRDGTLDKKAMREVADFLINKGVDGLFYL
                     GTGGEFSQMNTAQRMALAEEAVTIVDGRVPVLIGVGSPSTDEAVKLAQHAQAYGADGI
                     VAINPYYWKVAPRNLDDYYQQIARSVTLPVILYNFPDLTGQDLTPETVTRLALQNENI
                     VGIKDTIDSVGHLRTMINTVKSVRPSFSVFCGYDDHLLNTMLLGGDGAITASANFAPE
                     LSVGIYRAWREGDLATAATLNKKLLQLPAIYALETPFVSLIKYSMQCVGLPVETYCLP
                     PILEASEEAKDKVHVLLTAQGILPV"
     gene            10503..12470
                     /gene="yjhG"
                     /locus_tag="ROH59_004031"
     CDS             10503..12470
                     /gene="yjhG"
                     /locus_tag="ROH59_004031"
                     /EC_number="4.2.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylonate dehydratase YjhG"
                     /protein_id="HDX4806452.1"
                     /translation="MSVRNIFADESHDIYTVRTHADGPDGELPLTAEMLINRPSGDLF
                     GMTMNAGMGWSPDELDRDGILLLSTLGGLRGADGKPVALALHQGHYELDIQIKAAAEV
                     IKANHALPYAVYVSDPCDGRTQGTTGMFDSLPYRNDASMVMRRLIRSLPDAKAVIGVA
                     SCDKGLPATMMALAAQHNIATVLVPGGATLPAKDGEDNGKVQTIGARFANGELSLQDA
                     RRAGCKACASSGGGCQFLGTAGTSQVVAEGLGLAIPHSALAPSGEPVWREIARASARA
                     ALNLSQKGITTREILTDKAIENAMTVHAAFGGSTNLLLHIPAIAHQAGCHIPTVDDWI
                     RINKRVPRLVSVLPNGPVYHPTVNAFMAGGVPEVMLHLRSLGLLHEDVMTVTGSTLKE
                     NLDWWEHSERRQRFKQLLLDQEQINADEVIMSPQQAKARGLTSTITFPVGNIAPEGSV
                     IKSTAIDPSMIDEQGIYYHKGVAKVYLSEKSAIYDIKHDKIKAGDILVIIGVGPSGTG
                     MEETYQVTSALKHLSYGKHVSLITDARFSGVSTGACIGHVGPEALAGGPIGKLRTGDV
                     IEIKIDCRELHGEVNFLGTRSDEQLPSQEEATAILNARPSHQDLLPDPELPDDTQLWA
                     MLQAVSGGTWTGCIYDVNKIGAALRDFMNKN"
     gene            12577..13926
                     /locus_tag="ROH59_004032"
     CDS             12577..13926
                     /locus_tag="ROH59_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDX4806453.1"
                     /translation="MPLIIVVAGIALLLLLTIKIKLNTFVSLIIVSIAVAIASGMDLS
                     KVVTSVESGLGGTLGHIGLIFGFGVMLGRLLADAGGAQRIALTMLNYFGKNKLDWAVV
                     CSAFIVGIALFFEVGLILLVPILFAIAREAKISPMFMCVPMLSGLLVAHGFLPPHPGP
                     TVIAREYGADVGLVLIYGIIVGIPTFILCGPVLNKFCQRIIPDAFKKEGNIASLGATR
                     RFSESEMPGFGISFLTAMLPVILMAVVTIIQMTHAKSAADSGLFYNVILFLGNSTIAM
                     LISLLFAIYTMGLGRGKTIPDLMDSCGKAIAGIAGLLLIIGGGGAFKQVLIDSGVGQY
                     ISTLVSGMDINPILMAWGVAAFLRICLGSATVAAISTAGLVIPLLAVHPNTNLALITL
                     ATGAGSCICSHVNDASFWMIKDFFGLTTKETLLSWTLMSTLLSISGLIFILLASLVL"
     gene            14273..15259
                     /locus_tag="ROH59_004033"
     CDS             14273..15259
                     /locus_tag="ROH59_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDX4806454.1"
                     /translation="MDRDQTNSSLFNDDPVLHATWLYYQEGKSQTEVAAIMGVSRVTV
                     VKYLQTARENGLVHINLDVNVFGSIDAALQIRDKFNLQRVIIVPDGEHAGKRDDTKLM
                     RTRLSRAGGMYLNQVIENGDVLGVAWGRTIHQMSKTMTPKSCKNVTVIQMLGSMPSQP
                     DLTIIESSSQIAYKLSGRVASLHVPAVVSSARLAMELQAEPIIRSNFDVLTRCTKAFF
                     VVGNALDENPLIRVGVLNKKEMQTYRDLGAVGVICGRFYDKEGMPVVADVDQRILGIS
                     LAQLRQIERKIFLAGGERGYDATLGALLGGYVTDLIVDEGTAEFLLACELPH"
     gene            complement(15300..16304)
                     /locus_tag="ROH59_004034"
     CDS             complement(15300..16304)
                     /locus_tag="ROH59_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug DMT transporter permease"
                     /protein_id="HDX4806455.1"
                     /translation="MFIVESYAVAIIMCFITMICWGSWANTTKLVSNKKWEFPLFYWD
                     YSIGLLLCSLLFAFTLGSMGEAGRSFIPDIQQASSSSLMSAILAGIIFNISNILLVAS
                     INLAGMAVAFPVGVGLALALGVITTYIGNPQGDPLILFLGVACVVSAIIFTAIAYGRV
                     TQEADKSRRNKGLITAILAGIIMGWFFRFLADSMSDNFSQPASGLMTPYSALVLFAVG
                     LFLSNFVLNTLVMKKPISGEPVNGKMYFSGSLRDHVCGWLGGMIWCVGLAFSLIASGQ
                     AGYAISYGLGQGATMIAVIWGVFIWREFASAPAGTNKLLLTMFISYIVGIVLIIAANQ
                     "
     gene            complement(16408..17049)
                     /locus_tag="ROH59_004035"
     CDS             complement(16408..17049)
                     /locus_tag="ROH59_004035"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HDX4806456.1"
                     /translation="MERIKLAEKIISTCREMNASGLNQGTSGNVSARYTGGMLITPSG
                     IAYSKMTPDMIVFVDDKGIPEAGKIPSSEWLFHLACYKARPELNAVIHTHAVNSTAVA
                     IHNHSIPAIHYMVAVSGTDHIPCIPYYTFGSPELADGVSKGIRESKSLLMQHHGMLAM
                     DVTLEKTLWLAGETETLADLYIKCGGLHHDVPVLSEAEMTIVLEKFKTYGLKA"
     gene            complement(17080..18195)
                     /gene="mtnA"
                     /locus_tag="ROH59_004036"
     CDS             complement(17080..18195)
                     /gene="mtnA"
                     /locus_tag="ROH59_004036"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HDX4806457.1"
                     /translation="MNIKGKHYRTVWVSGDGKAVEIIDQTKLPFKFEVVALTSAEMAA
                     TAIQEMWVRGAPLIGVVAAYGIALGMNHDASDMGLQRYYDLLIKTRPTAINLKWALDR
                     MIDTLKDLCVSERKDVAWALAAEIAEEDVALCEQIGLHGTEVIREIAQKKPAGSVVNI
                     LTHCNAGWLATVDWGTALSPIYKAHENGIPVHVWVDETRPRNQGGLTAFELGSHGIPH
                     TLIADNAGGHLMQHGDVDLCIVGTDRTTARGDVCNKIGTYLKALAAHDNHVPFYVALP
                     SPTIDWTIEDGKSIPIEQRDGKEQSHVYGINPQGELSWVNTAPEGTRCGNYAFDVTPA
                     RYITGFITERGVCAASKSALADMFADLKSKALQGEQH"
     gene            complement(18205..19464)
                     /locus_tag="ROH59_004037"
     CDS             complement(18205..19464)
                     /locus_tag="ROH59_004037"
                     /EC_number="2.7.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000132329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose kinase"
                     /protein_id="HDX4806458.1"
                     /translation="MTDSIPSGYKPLTCDTLPGYLSSRLTPSCEPGGLPEEWKVSEVG
                     DGNLNMVFIVEGTHKTIIVKQALPWLRAGGEGWPLSLSRAGFEYNVLCQEAKYAGHTL
                     IPQVYFYDPEMALFAMEYLTPHVILRKELINGKKFPKLAEDIGRFLAQTLFNTSDIGM
                     SAEQKKALTAEFALNHELCKITEDLIFTEPYYNAERNNWTSPELDDAVHKAWADVEMI
                     QVAMRYKYKFMTEAQALLHGDLHSGSIMVTDTDTKVIDPEFGFMGPMAFDIGNYIGNL
                     LLAYFSRPGWDANEQRRADYQEWLLQQIVQTWSVFTREFRQLWDNKTQGDAWPTEMYQ
                     QNRAALEDAQDQFFATLLEDSLVNAGMEMNRRIIGFAGVAELKQIENTELRAGCERRA
                     LTMARDLIVNARQFKNMDSVIQSAKVK"
BASE COUNT         5035 a         5051 c         5051 g         5037 t
ORIGIN      
        1 atactcgcca gggatatgca attgaagcaa ttaccgccac gattgactgg ataaaagaga
       61 acggtttttc actcatcaaa gccggtgtga atccggaaaa taccctttca aaaaaattac
      121 ttatcaggat tggcttcaat ttttcgagca tcgaagatgg gtgagcatat ttatgttctg
      181 gattaaacaa aaggagaata atctcccgaa gggaaaagcc gatgaggcca tttcaggcgt
      241 acttcaacat gcattcgtca gtgtcatctg ccttttccag taaatgggtt ggcattcaat
      301 ttccaaagta catcacactt tttctactga aacatatccc tcctataact acgtgttaat
      361 attcgctccg taaatacctt tcaactcaac ccgaggcttt gatgctggag aatgtaatca
      421 tccgataatc agttccccga ccttttcagg ccggactgat tatcaatgcg ccgaaatcga
      481 atgcggacac cgcggtgtgt ttgcacgttt tgcacatgat gattaaacag gttcttcagt
      541 atgaatttat cccgtcagga acaacgtacg ttacacgttc tcgctaaagg tggacgtatt
      601 gcgcacgtcc gcgattcttc aggccgcgtc acttccgttg aatgctacag ccgcgaaggg
      661 ctgttgctga ccgactgcac gctcgccgtc ttcaaaaaac tcaaaaccaa aaaacttatc
      721 aagtccgtca atggtcagcc ctatcgaatc aacactaccg ggctgaataa cgttcgcgct
      781 cagctcgata atcgctaagg agagtttcga tgacagcaca ccacttcact tttcaaatca
      841 cagatgaaag tgatgccagt gatatccggg aagtcgaaac ccgcgcattt ggcttcagca
      901 aagaagccga tttaacggcc tctttacttg aggatgaaag cgcgcgccct gcgttatcgc
      961 tgctggcccg acatgaaggc aaagccgtcg ggcatatttt atttacccgg gcaaccttca
     1021 aaggggaaat ggattcaccg ctgatgcata tcctcgctcc cctggcagtc ataccggaat
     1081 accaggggat gggcgtggga ggacggttga tacgcactgg catcgagcac ctgaggttga
     1141 tgggctgcca gacggttttt gttctcggcc acgccaccta ttacccccga catgggttcg
     1201 aaccctgtgc cggagacaaa ggctatccgg caccttatcc catcccggag gagcacaaag
     1261 cctgctggat gatgcaagca ctcaccgctc agcccatgaa cgtgaccggc cacatccagt
     1321 gcgcgcaggc cctgatgaaa ccggagcact ggcgtgaata acaatcttgt tgtgcccttt
     1381 ttaatgctta acccaataac aggaattaac taatggatat tccacgtatt tttaccatca
     1441 gtgaaagcga acaccgcatc cacaacccgt tcaccgaaga gaagtacgcc acgctgggtc
     1501 gcgtgctgcg catgaaacca gaaacccgaa ttctggacct cggcagcggc tcgggcgaga
     1561 tgctctgcac ctgggcccgg gatcatggca ttacggggac tggaatcgac atgagttcgc
     1621 tcttcaccgc gcaggccaga cgccgcgcgg aagaactcgg cgtcagcgaa cgcgtacatt
     1681 ttattcataa tgatgcggcg ggttacgtcg ccaatgaaaa atgtgacgta gcagcctgcg
     1741 ttggcgcgac ctggattgcc ggaggctttg ccgggacagt cgaactgctg gcgcagagcc
     1801 ttaaaccggg cgggatcatg ctcatcggtg aaccttactg gcgtcagctt ccggcaacgg
     1861 acgagatagc ccaggcctgt ggcgtcagct cgacgaccga ttttctgacg ctaccagggc
     1921 ttgtcagcgc gtttgacgac ctcggctacg acgtggtgga aatggtactg gcggaccagg
     1981 aaggctggga ccgatatgag gccgcgaaat ggctgaccat gcgccgctgg ctggaggcca
     2041 atcctgacga tgacttcgcc gccgaagtca gggccgagct aaacatctcg ccgaaacgcc
     2101 acgtaacgta cgcgcgggaa tactttggct ggggcgtgtt cgcactcatc gctaggtaac
     2161 aacaggttcc cggtatttct gactggagat accgggggct tagcctttgc tttaatctga
     2221 tgcatcacct gcacaataca tattcagtat gtttattaat caagatgtca ccataaggag
     2281 catcatatgt cacaacatga acagttctgt caggcttgcg gaatgccgat gtcggcacca
     2341 gatgcacaca gtgccagtga tcaatattgt gcgtactgca gcgacagcaa cggcaatctc
     2401 aaaccctggg aagaagcggt atcaggttta gccagcttcc ttgattcctg gcaaaaagtc
     2461 ggcccggagg aagcacataa gcgtgcaaaa cgttatctga cggcaatgcc agcctgggct
     2521 cataaagcgg agagtgattt gagctgatta tctatactcc ctctgaatct attcaggaga
     2581 tccgatgttt tcttacatta tgctgggaac caacgacctg ccacgcgcca ttacattcta
     2641 agatccgctg atggagatgc tggggtatcc acgtgcagga cgtaatgaag agggagcgtc
     2701 ctgcaacaaa gtggtgcgat aacagttacc gcgttttatt cattctcatt atttcaacca
     2761 taatcactgg tctctctagc ccgtaacttt cacaaacgtt gagcgctttt attccactcg
     2821 gctcacataa ttttttattt gttcagcttt gcgcgttttc acgtgaacgt tctcacaatt
     2881 attcgaccag tctgcgccta taaaacgctc aacgagtgat tgttttacgg tctacggaga
     2941 tagctatgtc attttctgtg caggaaaccc tgttctcgct tttgcagcac aatgcgattt
     3001 caggacacga aaacgctgtc gctgacgtca tgctgtgcga attcaggcgt caggcaaaag
     3061 aggtctggcg agacaggctt gggaatgtcg tcgcgcgcta cggtagtgat aaacccgatg
     3121 cgctgcgact gatgattttt gcgcatatgg atgaagtcgg ttttatggtg cgcaaaatag
     3181 agccttctgg atttttacgc tttgaacgcg taggcggtcc tgcgcaggtc actatggctg
     3241 gatccatcgt caccctcacc ggggacaaag ggccagtcat ggggtgtatc ggcattaagt
     3301 cctaccactt tgccaaaggc gacgagcgca cgcagtcacc ttctgtcgac aaactgtgga
     3361 ttgatattgg tgccaaagac aaagacgacg ctatacgaat gggcattcag gtcggtacgc
     3421 ctgtcactct gtataacccg ccgcaactcc tggcaaacga tctggtgtgc agtaaagcac
     3481 tagacgatcg tctgggctgt actgccctgc tcggtgtagc ggatgctatc agtactacgg
     3541 agcttgatat cgccgtttat ctggtggctt cggtacagga agaatttaat atccgcggca
     3601 ttgttcccgt attacgccgt gtaaaacctg acctggcgat tggtattgat atcactccat
     3661 cgtgtgacac ccctgattta cacgattatt ccgaggtcag gattaatcag ggcgttggga
     3721 tcacctgcct gaactaccat ggtcggggaa cgctggccgg attaatcacg cctcctcgcc
     3781 tgatacggat gttggaacag acggctcttg aacacaacat tccggtgcag cgagaagtgg
     3841 ctcccggcgt gataacagaa accggttata tccaggttga gcaggatggt attccctgcg
     3901 ccagtctctc tattccttgt cgctataccc attctccggc ggaggttgcc agcctgcgtg
     3961 atttgactga ttgcatccgc ctattgaccg ctctggcagg tatgtcagca gcacatttcc
     4021 ccgttgagcc tgattcaggc actacacaag aggcacatcc attatgaaaa agatccttgt
     4081 ggcatgcggt accggcatgt cgacttcaac catgattgca cacaagctgc aagagttcct
     4141 gactgaacag ggcatttcag ccactaccgc ccaatgctgt ctgaatgaga tccctcttaa
     4201 ctgtaacggt atggacctta ttgtaacctc catgcgaacc aacagtgatt acggcatccc
     4261 tacgcttaat ggcgccgccc tgctcacagg gatcaacgac gacgcgttaa aacaacaaat
     4321 caaggctctg ttaactcaat aaaaggaggc attatgtttg attacatcct gtctctcggc
     4381 ggtaccgttt tcgtccctat catcatgatc gtgattggcc ttatcttccg catcccctgg
     4441 ctgcaggcga ttaaggcagg ggtaacggtt gggattggtt ttgtcggtat gggactggtg
     4501 atcgtcatgg cgatcgacag cctcagtccc cctatcaaag tgatgattga gcgtttcggc
     4561 ctggccctgc atgtctttga cgttggcgca ggccctgcct ccggcgttgg ttatgcgaca
     4621 gccattggcg ccatgattat cccagttatt tttcttctca atgtcgccat gctggtcacc
     4681 cgtctgacca aaacgatgaa cgtcgatatt tacaattact ggcactacgc cattacgggt
     4741 acggtggtcc agcttatgac cggtagcctg atttatggtg tgctgggggc aatctgccat
     4801 gcggcgctat cgttaaaaat ggccgactgg acggcaaaac gggtacagaa catcgtcggg
     4861 ctggaaggta tttcgatacc gcaaggctac ggttccagtt cagtaccgct tttcgttcta
     4921 cttgatgcta tctatgaaaa aatccctttc atgaagggac gcaatatcga tgctcaggag
     4981 atccagaaac gctacggcat ggtcggcgat ccggtgatta tcggcgtagt gctcggtctg
     5041 atttttggcc tggcggctgg tgaaggcttt aaaggttgcg ccagtctgat gattaccgtt
     5101 gcggcaatca tggtgctgtt cccgcgcatg atccgcctga ttgttgaggg cctgatgccc
     5161 atctccgacg gtgcaagaaa gttcttccag aaatatttca aaggacgtga agtgtatatc
     5221 ggtctggata ctgctgtgac gctggggcat ccaaccacca ttgctgtcgg tctgctactg
     5281 atacccatta tgttaattct ggccagcatt ttaccgggca acaaagtgtt acccctcgca
     5341 gacctgccgg tagcaccgtt ctttatctgt atggctacgg ttatccaccg cggagacctg
     5401 gtcaggacgt tgataagcgg ggtcatcgtg atgattaccg tcctgctgat cgccacccag
     5461 ttcgcgcctt acttcactga aatggcgctc aaaggcggtt tcagttttgc cggtgaaagt
     5521 gcgcaaatct cagcgttgtc cgtgggcaat atgttcggtt ggtcgatttc tgaattgatg
     5581 tcgcttggga ttattggcgt tgtcgtggcg gtcggtattg tcgccagcgt cgtgctgttc
     5641 ttacgtaaac gtgaattatc ggaataagga gtactttcaa tgagttggct gaaagaggtt
     5701 attgggacgg aaaaagcggt catcgccatg tgccatctac gtgcattgcc cggcgacccg
     5761 agttttgatg cgcagttggg gatgaactgg gttatcgaca aagcctggga cgatctgatg
     5821 gcgctccaaa atggtggggt ggatgcagtc atgttctcca acgagtttag tcttccctat
     5881 ctcacgaagg tgcgtccgga aaccactgcg gcaatggcac gaatcatcgg gcaattaatg
     5941 agcgatatcc gcatcccgtt tggcgtgaat gttctgtggg atccggtcgc ctcattcgac
     6001 ctggcgatgg ctaccggcgc taagtttatc cgcgagatat ttaccggtgc ctatgccagc
     6061 gactttggcg tctgggacac taacgtcggt gagaccatcc gtcatcaaca ccggattggt
     6121 gcaggcgaag tgaaaacctt gttcaatatc gtcccagagg ccgccgtgta tctgggcaat
     6181 cgcgatatct gttctattgc taaatcgaca gtatttaaca accatcctga tgcgctctgt
     6241 gtttctggcc tgaccgccgg gacgcgtaca gacagcgcgc tgttaaaacg ggtcaaagaa
     6301 acggtgcctg acaccgtcgt gttggccaac acgggcgtct gcctggaaaa cgtggaggaa
     6361 caactcagta tcgccgatgg ctgtgtgacc gcaaccacct ttaaaaagga cggcgttttt
     6421 gccaatttcg ttgaccaggc gcgagtcagt cagtttatgg agaaagtgca tcatatacgc
     6481 cgataagata gggataagca gagcgcttat ccccggcaaa gagcaataac ccttctgcga
     6541 tccctgccgc cttcgtcaaa agtatcgacg gggatcgcta ccagattaac ccgaatcggc
     6601 atggagtcaa cgacggatga ttaacgatat taaatgggta caggcacaac gtgaagccac
     6661 cgactggcgt caggccgtgg aaatcgccac ccgcccgctg gtagcctatg gtgccgcgca
     6721 gccatgctac gttaatggga tcatcgaaaa tacccttaac tgggggcctt attatctgat
     6781 agccccagga atcgccttgc ctcacgcccg accagagcaa ggcgcaaact ataatcaggt
     6841 cagtatcacc acgctacgca ccccggtcgc ctttggtaac gaggagtgcg accccgtctg
     6901 gctgcttctc tgcgtcagcg ccacagatgc caacgcacat attttgacca ttcagcgcat
     6961 cagccagttt attgattcgc cacaacgctt agcggcagtg ggaaatgcca gcacagacga
     7021 tgcactgttt gcgctggtat caggttaacg gaggcgctta tgatcctgca cccttctctc
     7081 gccagcgcaa atcctctgca ctatggtcgt gagctgacgg cattggacaa tctggatttt
     7141 gggagcctgc atctggatat tgaggacagc agcttcatta acaacattac gtttgggatg
     7201 aaaacggtgc aggccgtcgc cagacagacg cctcatccct tgtcctttca tttcatggtt
     7261 gcccggccac agcgctggtt taacgcgctg gctgaaatca gacccgcgtg gatcttcgtt
     7321 catgcagaaa cgctggacta tccttcggaa acgttaactg agatccgcca taccggcgca
     7381 cgagccggac tggtatttaa tccggcaacc ccgatcgacg cctggcgata tctggcgtct
     7441 gagctggacg gagtgatggt gatgaccagt gagcccgatg ggcagggaca gcggtttatt
     7501 ccctccatgt gcgagaaaat ccaaaaagta cgcacggctt ttcctcagac cgagtgctgg
     7561 gccgacggtg gaattacgct ggcagctgca cagcaactgg cagcagccgg ggcgcaacat
     7621 atggtgattg ggcgcgccct gttctcttca tctgactatc gcgcgacctt agctcaattc
     7681 gccaccctgt aagaggagat tgtttctgat gagccaacag agacctgacc gtatcaaaca
     7741 gatgctgcac tacctgtggc aacatcgtca cctctccaca cagcaggcca tggagctttt
     7801 tggctatgcg gaagcgactg tccgtcgtga tttccagtat attgccaacc agtatccagg
     7861 catgatccgc ggtcacggtt gcctggactt cgacgacagt acagacgaca aagagtacgt
     7921 cttcgacgtg aaacgtacat tgcaatctgt ggcgaaaaga gaaatagctg cccttgcccg
     7981 aacaatgatc aaagatggcg actgcttttt tctcgactcc ggctcaacct gcctcgaact
     8041 ggcgaaatgc ctggccgatg cgcgggtaaa ggtcatctgc aacgacatta aaatcgccaa
     8101 tgaactgggc tgttttcccc atgtggaaag ttacattatc ggaggactga ttcgcccagg
     8161 ttatttttcg gtaggagaga gtctggcgct ggagatgatc aatgcctttt ccgtagaacg
     8221 tgcgtttatc tcctgcgatg cgctgtcgct ggagacgggg atcaccaatg ccaccatgtt
     8281 tgaggtcggg gtgaaaacac ggattattca acgctcgcgt gaagttattc tcatggccga
     8341 tcactcaaaa tttgatgccg ttgagccgca tgctgtagca acactatcat gtattaaaac
     8401 gatcatcagt gacagcgggt tacctgagac tattgcacag cgttatcagc gagccggatg
     8461 tcagttgttt ttacctcatt caataaagtg ataagtaagt tcgttcgaga gggatttcaa
     8521 gcaaaaataa tcaatggcac ccaatagaaa atattggcga tgcgctcgaa cgaataaaga
     8581 agccctatgc gcaatccaca cgctacgatg ttgcaacaac acgccatcta ctttttattc
     8641 tcattcacta aatgtggttg ttctggattc attattcaaa gtgtgtacaa gatcacattt
     8701 aatcacttca ttacagttca gcatgctgaa caaagcatat tttccactat gtaatgccga
     8761 taccatttat tccatgagca agaaggagcc attatggttc gcaaagggtg taattcatta
     8821 gtccgtgctg aaaaaatatt aacccacatt gcatgggttg gtatggcaag ttatatggag
     8881 ttattaaata aattccagta ccccaaaagc agcctgctta atttattgaa tgtaatggtg
     8941 gagtgtggtt tcttaattaa aaacaaaaac ggctactatt cactgggaat aaaaaactac
     9001 gaattgggtt gtcaggcgtt acaccgtcaa aatatatttg aggtgactaa gcggccaatg
     9061 caggagttgt cgctgaaaag tggactggtt tgtcatcttg gggcgatgga gagcatttcg
     9121 gctatctatc tcgacaagat cgaaagtccg gactctgtac cgacgagcaa aagctggatt
     9181 ggcaaaaaaa ttgagttgca tattaccgcg ttgggtaagg cattattagc ctggaagaca
     9241 cgagaagaac tggattattt tttagaagca ctcacgttaa ctccacatac gcgcaataca
     9301 tttaccgata aaaaattgtt tctggaagaa ttacaaaaaa cacgccttcg gggatgggcc
     9361 atagacaacg aagaatcaac ctatggggcg gtatgtttaa gtatgccggt attcaatatg
     9421 tataacagag ttaactatgc aatctcactt tctggcgatc cggtagttta ttcaggaaat
     9481 aagatagaca gctatctgga attgctccgg aaatgcgctg agcaaatatc atatgggctg
     9541 ggatacagaa acgaaaatga gcatttacga aaaggaaact gaggtaatga aaaaattcag
     9601 cggcattatt ccaccggtat ccagcacgtt tcatcgtgac ggaacccttg ataaaaaggc
     9661 aatgcgcgaa gttgccgact tcctgattaa taaaggggtc gacgggctgt tttatctggg
     9721 taccggtggt gaatttagcc aaatgaatac agcccagcgc atggcgctcg ccgaagaagc
     9781 tgtaaccatt gtcgacgggc gagtgccggt attgattggc gtcggttccc cttccactga
     9841 cgaagcggtc aaactggcgc agcatgcgca agcctacggc gctgatggta tcgtcgccat
     9901 caacccctac tactggaaag tcgcaccacg aaatcttgac gactattacc agcagatcgc
     9961 ccgtagcgtc accctaccgg tgatcctgta caactttccg gatctgacgg gtcaggactt
    10021 aaccccggaa accgtgacgc gtctggctct gcaaaacgag aatatcgttg gcatcaaaga
    10081 caccatcgac agcgttggtc acttgcgtac gatgatcaac acagttaagt cggtacgccc
    10141 gtcgttttcg gtattctgcg gttacgatga tcatttgctg aatacgatgc tgctgggcgg
    10201 cgacggtgcg ataaccgcca gcgctaactt tgctccggaa ctctccgtcg gcatctaccg
    10261 cgcctggcgt gaaggcgatc tggcgaccgc tgcgacgctg aataaaaaac tactacaact
    10321 gcccgctatt tacgccctcg aaacaccgtt tgtctcactg atcaaataca gcatgcagtg
    10381 tgtcgggctg cctgtagaga catattgctt accaccgatt cttgaagcat cagaagaagc
    10441 aaaagataaa gtccacgtgc tgcttaccgc gcagggcatt ttaccagtct gaggagaaac
    10501 tcatgtctgt tcgcaatatt tttgctgacg agagccacga tatttacacc gtcagaacgc
    10561 acgccgatgg cccggacggc gaactcccat taaccgcaga gatgcttatc aaccgcccga
    10621 gcggggatct gttcggtatg accatgaatg ccggaatggg ttggtctccg gacgagctgg
    10681 atcgggacgg tattttactg ctcagtacac tcggtggctt acgcggcgca gacggtaaac
    10741 ccgtggcgct ggcgctgcac caggggcatt acgaactgga catccagata aaagcggcgg
    10801 ccgaggttat taaagccaac catgccctgc cctatgccgt gtacgtctcc gatccttgtg
    10861 acgggcgtac tcagggtaca acggggatgt ttgattcgct accataccga aatgacgcat
    10921 cgatggtaat gcgccgcctt attcgctctc tgcccgacgc gaaagcagtt attggtgtgg
    10981 cgagttgcga taaggggctt ccggccacca tgatggcact cgccgcgcag cacaacatcg
    11041 caaccgtgct ggtccccggc ggcgcgacgc tgcccgcaaa ggatggagaa gacaacggca
    11101 aggtgcaaac cattggcgca cgcttcgcca atggcgaatt atctctacag gacgcacgcc
    11161 gtgcgggctg taaagcctgt gcctcttccg gcggcggctg tcaatttttg ggcactgccg
    11221 ggacatctca ggtggtggcc gaaggattgg ggctggcaat cccacattca gcccttgccc
    11281 cttccggtga gcctgtgtgg cgggagatcg ccagagcttc cgcgcgagct gcgctgaacc
    11341 tgagtcaaaa aggcatcacc acccgggaaa ttctcaccga taaagcgata gagaatgcga
    11401 tgacggtcca tgccgcgttc ggtggttcaa caaacctgct gttacacatc ccggcaattg
    11461 ctcaccaggc aggttgccat atcccgaccg ttgatgactg gatccgcatc aacaagcgcg
    11521 tgccccgact ggtgagcgta ctgcctaatg gcccggttta tcatccaacg gtcaatgcct
    11581 ttatggcagg tggtgtgccg gaagtcatgt tgcatctgcg cagcctcgga ttattgcatg
    11641 aagacgttat gacggttacc ggcagcacgc tgaaagaaaa cctcgactgg tgggagcact
    11701 ccgaacggcg tcagcggttc aagcaactcc tgctcgatca ggaacaaatc aacgctgacg
    11761 aagtgatcat gtctccgcag caagcaaaag cgcgcggatt aacctcaact atcaccttcc
    11821 cggtgggtaa tattgcgcca gaaggttcgg tgatcaaatc caccgccatt gacccctcga
    11881 tgattgatga gcaaggtatc tattaccata aaggtgtggc gaaggtttat ctgtccgaga
    11941 aaagtgcgat ttacgatatc aaacatgaca agatcaaggc gggcgatatt ctggtcatta
    12001 ttggcgttgg accttcaggt acagggatgg aagaaaccta ccaggttacc agtgccctga
    12061 agcatctgtc atacggtaag catgtttcgt taatcaccga tgcacgtttc tcgggcgttt
    12121 ctactggcgc gtgcatcggc catgtggggc cagaagcgct ggccggaggc cccatcggta
    12181 aattacgcac cggggatgta attgaaatta aaattgattg tcgcgagctt cacggcgaag
    12241 tcaatttcct cggaacccgt agcgatgaac aattaccttc acaggaggag gcaactgcaa
    12301 tattaaatgc cagacccagc catcaggatt tacttcccga tcctgaattg ccagatgata
    12361 cccagctatg ggcaatgctt caggccgtga gtggcgggac atggaccggt tgtatttatg
    12421 atgtaaacaa aattggcgcg gctttgcgcg attttatgaa taaaaactga aagcataaat
    12481 aaaaacatcc agacacctga attatccgac tctgcatcat tcgttatttg ctcagtcgga
    12541 taatgatggg tcgctaccct gttatgagag gacgttatgc cactaattat cgttgtggca
    12601 gggattgctt tactcctgct tttaaccata aaaattaagc ttaatacgtt tgtttcgtta
    12661 attattgtct cgattgctgt cgccatcgcc agtggtatgg atttgagtaa agtcgtcacc
    12721 tcagtcgaat ccgggcttgg cggtacgctg ggccatattg gtttgatatt tggcttcggt
    12781 gttatgctcg gtcgcttgct ggccgatgcg ggtggtgcgc agcgaatagc gctgaccatg
    12841 ctgaattatt tcgggaaaaa taaacttgac tgggcagtgg tctgttcggc gtttattgtc
    12901 ggtatcgcac tttttttcga agtcggttta attcttctgg tacctatttt attcgctatt
    12961 gcccgtgaag caaaaatatc accgatgttt atgtgtgtgc cgatgctttc tggtttgctg
    13021 gtcgcacacg gttttttgcc gccgcacccc ggcccgactg ttatcgccag ggaatatggc
    13081 gctgatgtag gattggtact gatatacggt atcattgtcg gcattccaac ctttattctt
    13141 tgcggcccgg tattgaataa attctgccag cgcattattc cggacgcctt taaaaaagag
    13201 gggaatatag cctctctcgg cgcgacccgc cgattcagcg aaagcgaaat gccaggcttt
    13261 gggatcagtt ttctcacggc aatgctgccg gtgatcctga tggcggttgt caccatcatc
    13321 cagatgactc atgccaaaag tgccgcggat tctggcttat tttacaacgt gatactgttc
    13381 ttaggtaatt cgacgatcgc catgctgatt tcactgctgt tcgcgatcta taccatgggc
    13441 ctggggcgcg ggaaaacaat ccctgacctg atggattctt gcggaaaagc tatcgcgggt
    13501 attgccggtc tgctgctgat tatcggtggt ggtggtgcat tcaagcaagt tctcatcgac
    13561 tctggcgttg gtcagtatat ttccaccctg gtttcgggta tggatattaa cccgatcttg
    13621 atggcctggg gcgtggccgc attcctgcgt atttgtctgg gttcagccac cgtcgcggcg
    13681 atctctaccg ccggtctggt catcccattg ttggcagtac atcccaatac caacctggcc
    13741 ttgattacgc tggctaccgg tgccggatcc tgtatttgtt ctcacgttaa cgatgccagt
    13801 ttctggatga ttaaagactt ttttggcctg accaccaaag aaacgctgtt atcctggacg
    13861 ttgatgtcca cactcttatc catcagtggg ctgattttta ttctgctcgc cagcttagtt
    13921 ttataatcgg gttcttgcca gtgagccaac ctgttgttca ctgtccccca taatttagtg
    13981 agtgacggca accgtctgca cggtgacgaa tcgctggcga tcaaaaaggg gcgatattga
    14041 accgtcgatt atgcttgatg ggtgtactct cagtaatact gtaaagccgg agcatgtctc
    14101 cgactttaca gtatggggga acagcaggcg atcgctcaaa tggtatgctg gtttatttca
    14161 tgtaaaagaa taaaatatct gtataaaatc atgccactgg caatctgcat caactctccg
    14221 ggtaaacagg gttaagatga gcatttcccc ggtttaatac aggtatacaa aagtggatag
    14281 agatcaaaca aacagcagcc tgttcaatga tgatcccgta cttcatgcaa catggctgta
    14341 ctatcaggaa ggcaaaagcc agactgaagt tgcagctatc atgggggtgt cccgcgtcac
    14401 ggttgtcaaa tacctgcaaa cagcccggga aaatggactg gttcatatca acctggatgt
    14461 gaatgtcttt ggctctatcg acgctgcttt gcaaattcgc gataaattca atctccagag
    14521 agtgatcatc gtgccggatg gcgaacatgc cggaaaacgt gatgatacaa agctgatgcg
    14581 gactcgcctt tcacgtgccg gtggcatgta tctgaatcag gtgattgaga atggtgatgt
    14641 gctgggggtt gcctggggaa gaacaatcca tcagatgagc aaaaccatga cgccgaagtc
    14701 atgtaaaaat gtcaccgtta tacagatgct cggttccatg ccatctcagc cagacctgac
    14761 gatcattgaa tcctcatcgc aaatcgccta caagctttca ggccgtgtcg cctcgctgca
    14821 cgtgcccgcc gtggtatcaa gcgccagact ggccatggag ttacaggcag agcctattat
    14881 tcgatcgaat tttgacgttc tgactcgctg tacgaaagcc ttttttgtcg tgggtaacgc
    14941 gcttgatgaa aatcccctga ttcgggtggg cgtgctgaat aagaaggaaa tgcagacgta
    15001 tcgggattta ggcgcagtag gtgtcatttg tggtcgcttc tatgacaagg aagggatgcc
    15061 cgtcgtggct gatgttgacc agcgtattct gggaatcagt ctggctcagc taaggcagat
    15121 tgaacggaag atcttccttg ctggtgggga aagaggctat gacgcaacgt tgggtgccct
    15181 gctgggagga tatgtcacgg acctgattgt tgatgaagga acggcagagt ttttgctggc
    15241 gtgtgaatta ccacactaaa agaatgaaca actgccccat gtggatatgg ggcaggattt
    15301 tattgattag cggcgataat aagaacaata cccacaatgt atgaaataaa catggtcagc
    15361 agcagtttat tggttccggc tggcgcactg gcaaattctc tccagatgaa gactccccag
    15421 atcacggcaa tcattgtggc cccctgtccc agaccgtagg aaatggcata ccccgcctga
    15481 ccagacgcaa tcagactgaa tgccagaccg acacaccaaa tcataccgcc cagccagccg
    15541 caaacatgat cccgtaagct cccggaaaaa tacattttcc cgttgaccgg ttctcctgaa
    15601 ataggttttt tcatgaccag cgtgttaagg acaaagttcg acaagaacag ccccacggca
    15661 aacagaacaa gtgctgagta aggcgtcatc agaccgctgg caggctggct gaaattgtca
    15721 gacatggagt ccgccaagaa gcggaaaaac catcccatga tgatacccgc cagaatggca
    15781 gtaatgagac ctttattacg gcgagattta tccgcctcct gcgtgacacg accataggct
    15841 atcgcggtaa aaataatggc gctcacaacg caggcgacac cgaggaacag aatgagcgga
    15901 tcgccctgcg gattgccgat ataggtggtg atcacaccca gagccagtgc cagccccaca
    15961 cccacaggaa aagctaccgc cataccggca agattaatag aagcgaccag aagaatattg
    16021 gaaatattga agataatccc tgccagtatt gccgacatca gactactgct gctcgcctgc
    16081 tgaatatcag gtataaaact gcgaccggct tcgcccatag aacccagcgt gaaggcaaat
    16141 aacaaagaac acagcaataa tccaattgaa taatcccaat agaatagagg gaactcccat
    16201 tttttattgc tgacaagttt agttgtattc gcccatgaac cccagcaaat catggtaata
    16261 aaacacatta ttatggcgac agcatacgat tccacgataa acataaataa ctccttgtgg
    16321 tagttataat caatcgttgt ggacagaggg aatagcagcc attctgcgaa tggctgtcat
    16381 atgttattaa ttaaaataaa gctgtaatta cgctttcaaa ccatacgttt tgaatttttc
    16441 aaggacgatg gtcatttcgg cttcagacag cacgggaaca tcgtgatgta atccgccaca
    16501 tttgatgtat aaatcagcca gcgtctcggt ttcacccgcc agccacaacg tcttttccag
    16561 cgtgacgtcc atggccagca taccgtggtg ctgcatcagc aaggacttac tttctctgat
    16621 tcctttagat acaccgtcgg ccagttcagg actgccaaag gtataatagg gaatacaggg
    16681 aatatgatcc gtccccgata ccgccaccat ataatgaatg gccggaattg aatgattatg
    16741 tattgccacc gccgtggaat tcaccgcatg cgtatgtatg acagcattca attctggtct
    16801 ggctttataa cacgccagat gaaataacca ttcacttgat ggtattttac ccgcttcagg
    16861 tattccctta tcgtctacaa agacaatcat gtccggcgtc atctttgaat aagcgatccc
    16921 actcggcgta atcaacatgc caccggtata cctggcactc acattacctg atgttccttg
    16981 attaagacct gacgcattca tttcccgaca agtggaaatg attttttctg ctaacttaat
    17041 ccgttccatt cctgatcctt aatagcaatg gccgccgttt taatgctgtt ccccctggag
    17101 tgctttactc ttcaggtcag caaacatatc cgccagcgct gacttactgg cagcacagac
    17161 tccccgctca gtaatgaagc cggtaatgta tcgggcaggc gtgacgtcga aagcgtagtt
    17221 cccacaacgg gttccttcag gggcggtatt gacccagctc aattctccct gagggtttat
    17281 cccatagaca tgggactgct cttttccgtc acgttgctca atcggaatgc tttttccgtc
    17341 ctcgatagtc cagtcaatag tgggagaagg taacgcgacg tagaagggaa catggttatc
    17401 atgggccgcc agcgccttaa gataggtacc aattttatta cagacatccc ctctggccgt
    17461 ggttcgatcg gtcccaacaa tgcagagatc aacgtcaccg tgttgcatca ggtggccacc
    17521 cgcgttgtcg gcgatcaggg tgtgaggaat accgtgtgag cccagttcaa atgccgtgag
    17581 tccgccctga ttacgtggcc gcgtttcatc cacccagacg tgaacaggga ttccgttttc
    17641 atgcgctttg tagatgggag aaagcgcggt tccccagtct acagtcgcca gccagcctgc
    17701 gttacaatgt gtcaggatat tgaccacact cccggccggt tttttctggg ctatttcgcg
    17761 gatgacttct gtaccatgta atccaatttg ttcacacaac gcgacatctt cctcggcaat
    17821 ttctgccgcc agcgcccagg ccacatcctt gcgctctgat acacagagat ccttcagtgt
    17881 gtctatcatc ctgtcgaggg cccatttgag attaattgcc gttggtcggg ttttgataag
    17941 aaggtcatag taacgctgca gacccatgtc actggcatcg tgattcattc ccagcgcgat
    18001 gccataggct gcaacgacac caataagcgg agcgccacga acccacatct cctgaatagc
    18061 cgtagcggcc atttccgcag aggtaagcgc caccacctcg aacttaaaag gcaacttagt
    18121 ctgatcgatg atttctaccg cttttccatc cccggaaacc cagaccgtac gatagtgttt
    18181 acctttaata ttcataatga cctcttactt aaccttcgca gactggatga cggaatccat
    18241 atttttaaac tggcgggcat tgacgataag atcgcgcgcc atggtcaatg cacgtcgttc
    18301 acatcctgcg cgaagctctg tattttcaat ctgtttcagc tcggcaacgc cagcaaaacc
    18361 aatgatccgg cgattcattt ccatgccggc attcaccagg gaatcttcaa gcagcgtggc
    18421 aaaaaactga tcctgtgcgt cctcaagagc ggccctgttc tgttgataca tttctgtcgg
    18481 ccacgcgtcg ccctgtgttt tgttgtccca gagctggcgg aactcccggg tgaaaacgga
    18541 ccaggtttgg acaatctgct gaagcagcca ttcctgatag tcagcgcgac gttgctcatt
    18601 cgcatcccac ccagggcgtg agaagtacgc cagcaggagg ttgccaatat agttgccgat
    18661 atcaaacgcc attggcccca tgaaaccgaa ctccggatca atcactttgg tatccgtgtc
    18721 ggtcaccatg attgagcctg aatgaaggtc gccatgtaac aatgcctgcg cttctgtcat
    18781 aaatttgtac ttataacgca tggcaacctg gatcatctct acatcagccc aggccttatg
    18841 gacggcatcg tccagctcag gagaagtcca gttattccgt tcagcgttgt aatagggctc
    18901 tgtgaagatc agatcttccg taattttgca cagctcatga ttcaacgcga actcggcagt
    18961 aagcgctttt ttctgttctg ctgacatgcc aatgtcagac gtattgaaga gagtctgtgc
    19021 taaaaatctg ccgatatctt cagctagttt agggaatttt ttaccgttaa tcagttcctt
    19081 acgcagaatc acgtgaggag tcagatactc catggcaaac agcgccattt ccgggtcgta
    19141 aaaatagacc tgcggaatca gtgtgtgacc cgcgtacttg gcttcctgac ataagacgtt
    19201 gtactcaaag cccgcacggc tcagagataa aggccatcct tcgccccctg cacgaagcca
    19261 gggcagagct tgttttacaa tgatggtttt atgtgtcccc tcaacgataa acaccatgtt
    19321 caggtttccg tcccccactt ctgaaacttt ccactcttca ggtaaccctc ccggttcgca
    19381 tgaaggggtc agtctggacg agagataacc cggcagcgtg tcacatgtca gcggcttgta
    19441 acctgatgga attgaatccg tcataacagt tctccttgtc tacacagaat gataatcaac
    19501 ttgtcatgtg acaactatac attatcaaat gtaaaattat ttgtgacaca tgtagatttt
    19561 ttgaactgta taatattaaa aatgatgtcg tatggagtca tgatctttac aggaatcagc
    19621 agaggaaaac atctattatt accatgtaat tcatgttgtt atgtcgcaac aatagtactg
    19681 cacggggaat tattacgggc aaacttaggc gaaaggaagt actgaagtga cagaataaat
    19741 cacacttttt gtacatatgt acttttctat tgtcttttgt tgtggaaaca aatagtgttt
    19801 gtcatgccga tgctaataga cagatagatt cgagggccaa cagccccatc atcatgatgg
    19861 agcaacagag gtgagtctaa cgtttccgca cttcttatcg atcggcacta acgatcaata
    19921 tcgataaact gatctatcaa aacgattatc tttcttgcaa cctgcctggt tatccttctc
    19981 ttacattgct cgcagaaaag cccttttatt acggttagtt atctagctga gacttgctac
    20041 gcccattttc catgtacccc aaatcacgag gtcacaaagg cgcggaaaga tgaagagatg
    20101 tgcacgttgc aacaaaaaaa gaagcgtcct tgaacagagg ctctcactcg ataaagaatt
    20161 ctgcgacgag tgct
//
LOCUS       DAPOXO010000092        19740 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.092, whole genome shotgun sequence.
ACCESSION   DAPOXO010000092 DAPOXO010000000
VERSION     DAPOXO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19740
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.092"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1211)
                     /locus_tag="ROH59_004038"
     CDS             complement(<1..1211)
                     /locus_tag="ROH59_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HDX4806459.1"
                     /translation="MLRYLYVITHEVTMRLFSIPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQELT
                     LNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLAWLAAKAVAPRYAVIAAMIIGIVIVTAQGDVVTTDIVFKPVLPTYITPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALFFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLIAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLFGIGSAFWGLIAGGVCY
                     VVLNLIANRNR"
     gene            1264..1800
                     /gene="sutR"
                     /locus_tag="ROH59_004039"
     CDS             1264..1800
                     /gene="sutR"
                     /locus_tag="ROH59_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SutR"
                     /protein_id="HDX4806460.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQSATPSVYDPQRQAMVITSLFPYDPQLCFEHF
                     SIQMAPGAISESMPHEKGVIEHVVVIDGQLDLCVDGEWQSLNCGEGVRFAADVTHVYR
                     NGGEQTVHFHSLIHYPRS"
     gene            1873..3834
                     /gene="rlhA"
                     /locus_tag="ROH59_004040"
     CDS             1873..3834
                     /gene="rlhA"
                     /locus_tag="ROH59_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HDX4806461.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLEQIRAIHQATNATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVLKVAKDHIDV
                     AVTEPLANGDGLNVMIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWHQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSVTHTLDGQFDEANNA
                     EKAMNNLKDGLTKLGQTIYYARNVQINLPGALFVPNSLLNQFRREAADMLDAARLASY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDDLLKTLPKRKG"
     gene            complement(3926..4156)
                     /locus_tag="ROH59_004041"
     CDS             complement(3926..4156)
                     /locus_tag="ROH59_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2554 family protein"
                     /protein_id="HDX4806462.1"
                     /translation="MFSKALSVVLLTCALFSGQLMAGHKGHEFMWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            4335..4571
                     /gene="hicB"
                     /locus_tag="ROH59_004042"
                     /pseudo
     CDS             4335..4571
                     /gene="hicB"
                     /locus_tag="ROH59_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
     gene            4650..6056
                     /locus_tag="ROH59_004043"
     CDS             4650..6056
                     /locus_tag="ROH59_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDX4806463.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESQGYIIARPQSGYYVAPQAIKMPKATVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDIKEGIDLQALELALQEYPVKACWLMTNSQNPLGFTLTPQKKVRLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHNDSGYFLWLELPEPLDAGELSLVALTHHISIAPGNMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGKLIQERL"
     gene            6301..7446
                     /locus_tag="ROH59_004044"
     CDS             6301..7446
                     /locus_tag="ROH59_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX4806464.1"
                     /translation="MSKTFARSSLCALSMTIMTAHAAEPPTNLENPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMAKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKTLDPRVVKGDWFNVSGKVYGTPYQWGPNLLMYNTKTFPTPP
                     DSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRDQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPQGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPVAEGGKFVPYSRWTQDYIAIMGGR"
     gene            7464..8477
                     /locus_tag="ROH59_004045"
     CDS             7464..8477
                     /locus_tag="ROH59_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4806465.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGTPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVNKKQRHAMAQEALEKVALGFVQQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDPLMAEKLCGMTGSFALRPEHIRLNTHGEMQANGT
                     IQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVALV
                     EER"
     gene            8478..9419
                     /locus_tag="ROH59_004046"
     CDS             8478..9419
                     /locus_tag="ROH59_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4806466.1"
                     /translation="MAMNVLQSPSRPGLGKVSGFFWRNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIIVRTLTMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIVLIALYLAFVKRLGAFDAL"
     gene            9409..10203
                     /locus_tag="ROH59_004047"
     CDS             9409..10203
                     /locus_tag="ROH59_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4806467.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            10225..11649
                     /gene="patD"
                     /locus_tag="ROH59_004048"
     CDS             10225..11649
                     /gene="patD"
                     /locus_tag="ROH59_004048"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HDX4806468.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVNAA
                     VRAADAAFAEWGQTTPKARAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTAPSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGSPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDSE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
     gene            complement(11746..11841)
                     /gene="yncL"
                     /locus_tag="ROH59_004049"
     CDS             complement(11746..11841)
                     /gene="yncL"
                     /locus_tag="ROH59_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HDX4806469.1"
                     /translation="MNVSSRTVVLINVFAAVGLFTLISMRFGWFI"
     gene            12037..12210
                     /gene="ortT"
                     /locus_tag="ROH59_004050"
     CDS             12037..12210
                     /gene="ortT"
                     /locus_tag="ROH59_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orphan toxin OrtT"
                     /protein_id="HDX4806470.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRLLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            12296..12529
                     /locus_tag="ROH59_004051"
     CDS             12296..12529
                     /locus_tag="ROH59_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcY family protein"
                     /protein_id="HDX4806471.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTL
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(12530..12979)
                     /locus_tag="ROH59_004052"
     CDS             complement(12530..12979)
                     /locus_tag="ROH59_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX4806472.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLVLDIFRSHGVPLRALIGPICGAILLVVGAWLVARRSF"
     gene            complement(12976..13494)
                     /gene="mddA"
                     /locus_tag="ROH59_004053"
     CDS             complement(12976..13494)
                     /gene="mddA"
                     /locus_tag="ROH59_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HDX4806473.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTIAGYPVLVSEEDGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVTAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            13743..13898
                     /locus_tag="ROH59_004054"
                     /pseudo
     CDS             13743..13898
                     /locus_tag="ROH59_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310081.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(13975..16077)
                     /locus_tag="ROH59_004055"
     CDS             complement(13975..16077)
                     /locus_tag="ROH59_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDX4806474.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTP
                     AAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVATTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDDASKLSLIFNSVDIKADDPGGLTEAEWKANPQQAPRAEQYDMRKTI
                     KQTQAGLRYERSLSAQDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNRGVPEYGQKGELRRDERN
                     LMWNVDPYLQTQWQLTDKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNVYLAAGRGFETPTINELSYRADGQSGMNFGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVKA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYIPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PAPGRNYGVGINIAWRFE"
     gene            16319..17380
                     /locus_tag="ROH59_004056"
     CDS             16319..17380
                     /locus_tag="ROH59_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDX4806475.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVASSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWIATSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDTTNTVYISGI
                     GKESVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNADGELITIDTTDNKI
                     LSRKKLLDDGKEHFFINISLDTTNQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            complement(17493..18992)
                     /gene="ansP"
                     /locus_tag="ROH59_004057"
     CDS             complement(17493..18992)
                     /gene="ansP"
                     /locus_tag="ROH59_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HDX4806476.1"
                     /translation="MSKHNTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQDIVFKPETAS"
BASE COUNT         5009 a         4925 c         5045 g         4761 t
ORIGIN      
        1 tatcggtttc tgttagcgat taaattcaac accacgtaac aaacgcctcc ggcaattaat
       61 ccccaaaacg cagaaccaat cccgaacagc gtcaatccac ttgccgttac cagaaatgcc
      121 accaccgccg cgtcgcgctc acgctcatta tgcagcgcct gatacaaact gccgccaatg
      181 gtactcaaca gcgcaagacc tgccagcatc tggatccaac ttacgggcag ggcagccatc
      241 atcccggtaa tggcactacc aaacagacct gcgatcaaat aaaaaatgcc ggcaacggca
      301 gcggccagcc aacgttgatc tttatccgga tgcgcttccg ggctttggca aatagccgcg
      361 gtgattgccg caataccgac ggaataaacg ccgaaagggg aaaaaaacag tgccagcaat
      421 ccagtaaaca caatcaacgg cgaaacagga gccgaatacc cggctgcttt cattgctgcg
      481 atacccggtg cgttttgcga tgccatcgtc accagaaaaa gggggagtgc aacgctcaga
      541 ctgtgagcaa acgaaaaatc aggggtaata taagtgggga gaacgggttt aaagacaata
      601 tcagttgtaa caacgtcacc ttgcgcggta acgatgacga tcccaataat catcgcggca
      661 attaccgcat agcgcggcgc aacggccttg gctgccagcc atgccagcaa catactgcca
      721 cacaacgtaa attgaccatc cagactggca aacgcctgta aaccaaaacg taataaaatc
      781 ccggcaagca ttgccgccgc aagcgagtgc ggaataatgc gcatcagacg agcaaagagt
      841 cccgttatgc cgcagaggac tattaacgcg ttggtgacaa taaaaacgcc gatggcttcg
      901 ttaagtgtta gttcctgcaa tccggtgacc aacaaagccg cgccaggcgt tgaccatgcg
      961 gtgagaacag gtacgcgata ccataatgtc agagtcagcg tactgacgcc cattgccagc
     1021 cccagcgccg tcatccagcc agagatttgt gcagtggtgg ctccggcgac aatcgctgct
     1081 tgccagatta ttgccgctga actggcgtag ccaattaata ccgccagaaa ccccgccagt
     1141 agcgtgggtg gaggaataga aaacagacgc atagtcacct cgtgcgttat aacgtacagg
     1201 taccgtagca tttgtccgtt ataacgcaca agtgataaac ttccgttttg ccggaggagt
     1261 cgcatggaaa atctcgctcg ttttttatcc accacactta aacaactacg tcagcagcgc
     1321 ggctggagtc tttcgcgact ggcagaagcg acgggcgttt ctaaagcgat gttagggcag
     1381 attgagcgta atgaatccag cccgacggtc gcgacattat ggaaaattgc caccgggttg
     1441 aacgtgccat tttcaacatt tatttctccg ccgcagtccg ctacgccttc agtttatgat
     1501 ccacaacggc aggcgatggt gatcacttcg ctgtttcctt atgatccaca actctgcttt
     1561 gaacacttct cgattcagat ggcacccggt gcaataagcg aatcgatgcc ccatgaaaag
     1621 ggggtaatcg aacatgtcgt cgtcattgat ggacaacttg atctgtgtgt tgatggtgaa
     1681 tggcagagcc ttaattgtgg ggaaggcgtt cgatttgctg cagacgtcac gcatgtctat
     1741 cgtaatggtg gggagcaaac cgtacatttt cattccctca tccattaccc gcgcagttaa
     1801 gcgggaaaac tatttcgcaa cgtcgcgctt gtggctaaaa tagccgccat ttttcagcta
     1861 ctggataaga aagtgaccgt atcttctcat cgtcttgaac tgttaagccc ggcacgcgat
     1921 gccgccattg cccgcgaagc tattttgcac ggtgccgatg ctgtttatat cggcggccct
     1981 ggttttggtg cccgtcataa tgccagtaat agcctgaaag atattgccga gttggtgccg
     2041 tttgcccatc gttatggtgc aaaaattttc gtcacgctta acaccatttt gcatgatgat
     2101 gagctggaac ccgcgcaacg gctgattact gacctctacc agaccggtgt cgatgcgctg
     2161 attgttcagg atatggggat tctggaactt gatattccgc cgattgaact gcacgccagt
     2221 acgcagtgcg atattcgtac agtagaaaaa gcgaagttcc tctctgatgt tggcttcacg
     2281 cagattgtgc tggcgcgaga actgaatctt gagcagatcc gcgcgattca ccaggccacg
     2341 aacgcgacca ttgaattctt tattcatggc gcattgtgcg tggcctattc gggtcagtgc
     2401 tacatttctc atgcgcaaac agggcgtagc gccaaccgtg gcgattgctc gcaggcgtgc
     2461 cgtttgccat acacattgaa agacgatcag gggcgggtgg tttcctatga aaaacatctg
     2521 ctgtcgatga aagataacga tcagactgcc aacctcggcg cgctgattga tgctggcgta
     2581 cgctccttca agattgaagg gcgttacaaa gatatgagct acgtgaagaa tatcaccgcc
     2641 cattatcgcc agatgctgga tgccattatt gaagaacgtg gcgatctggc gcgcgcttca
     2701 tcaggtcgta ctgaacattt ctttgttcca tcgacggaaa agactttcca ccgtggtagc
     2761 acagattatt ttgtgaatgc ccgtaaaggc gatattggcg cgttcgattc gccgaaattt
     2821 atcggcctgc cggtgggcga agtattgaaa gtagcgaaag atcatattga tgttgccgtt
     2881 accgagccac tggcaaatgg cgatggcctg aacgtgatga ttaaacgtga agtcgtcggt
     2941 tttcgtgcca atacggtaga gaaaaccgga gaaaatcagt accgcgtctg gccaaatgaa
     3001 atgccagcag atttgcacaa aattcgcccg catcacccac taaaccgtaa tcttgatcat
     3061 aactggcacc aggcactgac aaaaacctcc agcgaacgtc gggtggcggt agacattgaa
     3121 ctgggcggct ggcaggaaca actgattctg accctgacca gtgaagaggg cgtcagcgtc
     3181 acgcatacgc tggacgggca gttcgacgaa gccaataacg ccgaaaaagc aatgaacaat
     3241 ctgaaggatg gtctgacaaa actggggcaa accatctatt acgcccgcaa tgtgcaaatt
     3301 aatttgccgg gggcgctgtt tgtaccaaac agtctgttaa accagttccg ccgtgaagcc
     3361 gccgatatgc ttgatgctgc gcgtcttgcc agttaccagc gcggcagccg taaaccggtt
     3421 gctgatcctg cgccggttta tccgcaaacg catctgagtt tcctcgcgaa cgtatacaac
     3481 cagaaagcgc gtgaatttta tcatcgctat ggtgtgcaac tgattgacgc ggcgtatgag
     3541 gcacatgaag agaagggcga agtcccggtg atgatcacca agcattgtct gcgctttgcc
     3601 ttcaatctgt gcccgaaaca ggcgaaaggc aatatcaaaa gctggaaggc gacgccaatg
     3661 caactggtta acggcgatga agtattaacg ctaaagtttg attgccgccc atgcgagatg
     3721 cacgtcattg gcaaaatcaa aaatcacata ctgaaaatgc cgttaccggg aagcgtagtg
     3781 gcatccgtaa gtccggatga tctgctgaaa acattgccga agcgaaaagg gtaaaacgcc
     3841 agttttcggg ttactcacca ctcatcaaat ctgcatgata ttgcctgccg ggtaaggcgt
     3901 catgccgcat ccggcaacaa atgactcaac gctgtcccgc ttctggtttg cgcgattttt
     3961 gccagtaaaa atgctcgcgc aaaccttccg ccgactcttc cgccacagca cgcaattcat
     4021 cgctgtccgc ttcatgacgc agctgatgat ccacattctt tacccacata aattcatgtc
     4081 ctttgtgccc tgccatgagt tgtcctgaga acagtgcaca cgttaataag acaaccgata
     4141 acgccttcga aaacatcccg ccaccttttt ctaacctttt gccgctatga tgccgatcgt
     4201 ttcttgaggt tattattcag ttttgcaaat tagagcaaag aaattctgga atcttccttc
     4261 ctgattttgc attgaattct gccgttgcgg cgatttagtg ctattttcga gcacattaca
     4321 cacggaggta aacttcgcca ttaaatagtc acgatcactt tattgaagtg cctttgagcg
     4381 tcgcctctaa tgtattgctg ttaaatgctt ttttacagtc agaaatcact cagcaagagt
     4441 tagccaggcg aattggcaaa cataaacagg agattactcg cctatttaat ttgcaccatg
     4501 cgacaaaaat cgacgccgtc cagctcgcgg ctaaggcgct tggcaaagag ttatcgctgg
     4561 tgatggttta attacagtta acgaaaagtt gtcattttta acaactgata tagactgccg
     4621 aatcatctgc acataattac gattcgataa tgaaaaaata ccagcagctt gcagaacaat
     4681 tacgcgagca gattgcgtcg ggtatctggc aacccggcga tcgtttgcct tcgttgcgtg
     4741 accaggtggc gctttctggc atgagcttta tgactgtcag ccatgcctat cagttgctcg
     4801 aaagtcaggg atatattatc gcgcgaccgc aatcgggtta ttacgttgcg ccacaggcaa
     4861 taaaaatgcc gaaagcgaca gtcattccag tcacacgaga tgaagcagtc gatatcaaca
     4921 cctatatttt tgatatgttg caggccagtc gcgatccgtc ggtagttccg tttgcctcgg
     4981 cctttcccga cccgcgactt ttccccctcc aacaactaaa ccgctcgctg gcgcaggtaa
     5041 gcaaaaccgc cacggcgatg agcgtgattg aaaacttacc gccaggaaac gcagaactgc
     5101 gtcaggctat tgctcgtcgc tatgccttac agggcatcac catttctcct gatgaaattg
     5161 tcattaccgc cggggcgtta gaggcattaa acctcagttt gcaagcggta actgaaccgg
     5221 gcgattgggt gatagtagag aatccttgtt tctacggcgc gttgcaggcg ctggagcggt
     5281 tacggctgaa ggcgttatcg gtagcgacgg atattaaaga agggatcgat cttcaggcgc
     5341 tggaactggc gttgcaggag tatccggtga aagcgtgctg gctgatgact aatagccaga
     5401 acccacttgg atttacctta acgccgcaga aaaaagtgcg gctggtagcg ttgctcaatc
     5461 agtacaacgt aacgctgatt gaagatgacg tttatagcga actttatttt ggacgggaaa
     5521 aaccgctgcc tgcgaaagcg tgggatcgcc acgatggtgt tttgcattgc tcttcgtttt
     5581 cgaaatgtct ggtgcctggt tttcgtattg gttgggtcgc cgccggaaaa catgcacgta
     5641 aaattcaacg cttgcagttg atgagtacgc tttccaccag ctcaccgatg cagcttgcgc
     5701 tggtggatta cctttctact cgccgatacg atgctcatct tcgtcgcctg cgtcgccagc
     5761 ttgcggaacg taaacaacgc gcctggcagg ctttgctgcg ttatctgcct gcggaagtca
     5821 aaattcatca caatgacagc ggttattttc tctggctgga gctccccgag ccgttagatg
     5881 caggagaatt aagcctggtg gcactgacgc atcatatcag tattgcgccg ggtaatatgt
     5941 tttctaccgg tgaaaactgg tcacgttttt ttcgttttaa taccgcgtgg cagtggggag
     6001 aacgtgaaga acaggcggta aaacaattag gcaaacttat tcaagaacgg ctgtaatagc
     6061 gtttaattta attcctctca ggttgggtaa tatgaatttc gaatagcagt catatatcct
     6121 aactccttgt ctatactcca gaagataacc ttacagacgg cataatgcgc ggtagctcac
     6181 aacctgatta aattttctca gggccgaagg tgtgcctgca agccgccgtc tatggttaaa
     6241 caaggagata tttttacggc acggcggctg aacaattaat tacgacagga gtaagacctt
     6301 atgagcaaga catttgcccg cagcagcctg tgtgcgctca gcatgacaat aatgaccgct
     6361 cacgccgccg aaccgcctac caatttagag aatccggaag ggcgactgga tattatcgcc
     6421 tggccgggat acatcgaacg cggacaaact gataaacagt acgactgggt aacgcaattc
     6481 gaaaaagaga caggctgcgc ggtgaatgtt aaaaccgccg cgacttccga tgaaatggtc
     6541 agtctgatgg ccaaaggggg ttacgatctg gttacggcat ccggcgatgc ctcgctgcgt
     6601 ttgattatgg gcaaacgcgt gcagccaatt aataccgcct tgattcccaa ctggaaaacg
     6661 ctcgatccgc gcgtggttaa aggcgactgg tttaacgtta gtggcaaagt ttatggcaca
     6721 ccttaccaat ggggtccgaa cctgttgatg tacaacacta aaaccttccc gacgccgccg
     6781 gatagctggc aagtggtttt tgttgagcag aatctgccgg acggcaagag caataaaggc
     6841 cgcgttcagg cttatgatgg ccctatctac attgcggacg ctgcgttgtt cgttaaagcc
     6901 actcagccgc agttgggcat cagtgatccg tatcaactca ccgaagaaca gtaccaggcg
     6961 gtgctgaaag tgctgcgcga tcaacatagt ttgatccatc gctactggca tgacactacc
     7021 gtgcaaatga gcgatttcaa aaacgagggt gtggttgctt ccagtgcatg gccctatcag
     7081 gccaacgccc tgaaagccga aggccagcct gtcgctaccg ttttcccgaa ggagggcgtt
     7141 accggttggg ctgacaccac catgctacat agcgaagcga aacatccggt ttgcgcctac
     7201 aaatggatga actggtcatt aaccccaaaa gtgcagggcg atgtggcggc ctggtttggc
     7261 tcgttaccag tagtgccgca agggtgtaaa gccagtccgt tattaggcga gaaaggttgt
     7321 gaaacaaacg gttttaacta tttcgataaa atcgccttct ggaaaacgcc tgtagcagaa
     7381 gggggcaagt ttgttcccta cagtcgctgg acgcaggatt acattgccat tatgggcggt
     7441 cgctaacttc gctggggtgt tttatgacgt acgcagtgga gtttgacaac gtctcacggt
     7501 tgtacggtga cgtgcgcgca gtagatggcg tcagtattgc gataaaagat ggtgagttct
     7561 tctctatgct ggggccgtcc ggctccggca aaaccacttg cctgcgcctg attgctggat
     7621 tcgaacagct ttccggcggg gctatctcta tttttggtac gcccgccagc aatctgccac
     7681 cgtgggagcg ggacgtgaat actgtcttcc aggactacgc gctatttccg catatgtcga
     7741 ttcttgacaa cgtagcctac gggctgatgg tcaaaggcgt gaataaaaag cagcggcatg
     7801 caatggcgca agaggcgctt gagaaagtgg cgttggggtt tgtacagcaa cgtaaaccgt
     7861 cacaactttc tggtggtcag cgccagcggg ttgctatcgc cagagcactg gtgaacgaac
     7921 cgcgtgtgtt gttgctggat gaaccgctcg gcgcgctgga tctcaaattg cgagagcaaa
     7981 tgcagcttga gctgaaaaag ctgcaacagt ctctcggtat cacttttatc ttcgttaccc
     8041 acgatcaggg cgaagcgtta tcgatgtccg atcgggtggc ggttttcaat aatggacgca
     8101 ttgaacaggt cgattctccg cgcgatctct atatgcgccc gcgcacgccg tttgttgcgg
     8161 gattcgtcgg gacatccaac gtttttgatc cgctaatggc cgagaaactt tgtggcatga
     8221 cgggaagctt cgcactacga ccggaacata tccgcctcaa cacccatggc gaaatgcagg
     8281 ctaatggcac gatccaggcg gtgcaatatc agggcgcagc gacccgtttt gaactgaaat
     8341 tgaacggcgg tgaaaaactg ctggtgagtc aggccaatat gacaggcgaa gagctacctg
     8401 ccacgctcac gcccggacaa caggtgatgg tttcctggtc acgtgatgtg atggtggcgc
     8461 tggttgagga gaggtgaatg gcgatgaacg tattgcaatc accttcacgt ccaggtctgg
     8521 gtaaggtgtc cggtttcttc tggcgtaatc cggggctggg gctgtttttg ctgctgcttg
     8581 gcccgctaat gtggtttggc attgtctatt tcggctcgct gctgacgctg ttatggcagg
     8641 gcttttatac ctttgacgat ttcaccatgt cggtaacgcc ggaactgacg ctggcgaata
     8701 tccgcgcgct gtttaatccg gcgaattacg acatcattgt ccgcacgctg accatggctg
     8761 tggcagtcac tatcgccagc gccattctgg cttttccaat ggcgtggtat atggcgcgct
     8821 ataccagcgg gaaaatgaaa gcgttttttt atatcgcggt aatgttgccg atgtgggcga
     8881 gctacattgt taaagcctat gcctggacgt tattgctggc aaaagatggc gtggcgcagt
     8941 ggtttttaca acatctgggg ctggaaccac tgctgactgc gttcctcacg ctaccggcgg
     9001 tgggaggtaa tacgctgtca acttccgggc tggggcgctt tctggtgttt ctctatatct
     9061 ggttgccgtt catgatcctc ccggtgcagg cggcgcttga gcgtttgccg ccgtcattgt
     9121 tgcaggcgtc ggctgatctt ggcgcacgtc cacgacaaac ctttcgctat gtggtgctgc
     9181 cgctggcaat cccgggtatt gccgctggct ctatctttac cttctcactc acgctgggcg
     9241 attttattgt cccgcagctg gttggccctc caggatattt tatcggcaat atggtttatt
     9301 cccagcaggg ggcgattggc aatatgccga tggcggcggc attcaccctg gtgccgattg
     9361 ttctcatcgc actttacctg gcgttcgtga aacgtctggg agcgttcgat gcactctgaa
     9421 cgcgcaccgt ttttcctcaa actggcggcc tggggcggcg tggttttcct acattttccc
     9481 atcctgatta tcgctgccta tgcgtttaac actgaagatg cggcgtttag ttttccaccg
     9541 caaggcctga cgctgcgctg gtttagcgtg gcagcacagc gtagtgatat ccttgatgcc
     9601 gtgacactgt cacttaaagt ggcggcgctg gcgacattaa tcgcgctggt gttagggacg
     9661 ctggcagctg ccgcgctgtg gcgacgagac tttttcggca aaaacgccat ttcgctgtta
     9721 ctgttgctgc ccattgcgct gccgggcatt gtcactggtc tggcgctatt aaccgccttt
     9781 aaaaccatca atctggagcc aggatttttc accatcgtgg tcggtcatgc gactttttgc
     9841 gtagtggtgg tgtttaacaa tgtcatcgcc cgttttcgcc gcacctcgtg gagtctggtt
     9901 gaggcgtcaa tggatcttgg ggccaatggc tggcaaacct tccgctacgt agtgttgccg
     9961 aatctcagtt cggcgttact ggctggagga atgctggcgt ttgccttgtc gttcgatgaa
    10021 atcatcgtga cgacttttac ggcaggtcat gaacgaacgt taccgttgtg gttgctcaat
    10081 cagcttgggc gaccgcgtga tgtaccggta accaacgtgg tggcactgct ggttatgttg
    10141 gtaacaacct tgccgatcct gggggcctgg tggctaaccc gcgaaggcga caatggtcaa
    10201 taaccactga tacaggaata tgctatgcaa cataagttac tgattaacgg agaactggtt
    10261 agcggcgaag gggaaaaaca gcctgtctat aatccggcaa cgggggacgt tttactggag
    10321 attgccgagg catccgcaga gcaggtcaat gctgctgtgc gcgcggcaga tgcagcattt
    10381 gccgaatggg ggcaaaccac gccaaaagcg cgtgcggaat gcctgctgaa actggctgat
    10441 gttatcgaag aaaatggtca ggtttttgcc gaactggagt cccgtaattg tggcaaaccg
    10501 ctgcatagtg cgttcaatga tgaaattccg gcgattgtcg atgtctttcg ctttttcgcc
    10561 ggtgcggcgc gctgcctgaa tggtctggcg gcaggtgaat atcttgaagg tcatacttcg
    10621 atgatccgtc gcgatccgtt gggggtcgtg gcttctatcg caccgtggaa ttatccgctg
    10681 atgatggctg cgtggaaact ggctccggcg ctggcggcag ggaactgcgt agtgcttaaa
    10741 ccatcagaaa ttaccccgct gaccgcgttg aagttggcag agctggcgaa agatatcttc
    10801 ccggctggcg tgattaacgt gctgtttggc agaggcaaaa cggtgggcga tccgctgacc
    10861 ggacatccca aagtgcggat ggtgtcgctg acgggttcta tcgccactgg ggaacacatc
    10921 atcagccata ccgcgccgtc cattaagcgt actcatatgg aacttggtgg caaagcgcca
    10981 gtgattgttt ttgatgatgc ggatattgaa gctgtggtcg aaggtgtacg tacttttggc
    11041 tattacaatg ccggacagga ttgtactgcg gcttgtcgga tctacgcgca aaaaggcatt
    11101 tacgatacgc tggtggaaaa actcggtgct gcggtggcaa cgttaaaatc gggttcgccg
    11161 gatgacgagt ctacggagct tggaccttta agctcgctgg cgcatctcga acgcgtcagc
    11221 aaggcggtag aagaggcgaa agcgacaggg cacatcaaag tgatcactgg cggtgaaaag
    11281 cgcaagggta atggctatta ctatgcgccg acgctgctgg ctggcgcatt acaggatgat
    11341 gccatcgtgc aaaaagaggt atttggtccg gtagtgagtg ttacgctctt cgacagcgaa
    11401 gaacaggtgg tgaactgggc gaatgacagt cagtacggac ttgcatcttc ggtatggacg
    11461 aaagatgtgg gcagggcgca tcgcgtcagc gcgcggctgc aatatggttg tacctgggtc
    11521 aatacccatt tcatgctggt aagtgaaatg ccgcacggtg ggcagaaact ttctggttac
    11581 ggcaaggata tgtcacttta tgggctggag gattacaccg tcgtccgcca cgtcatggtt
    11641 aaacattaag gataatattg cagatcgtaa gagtatgaga tgatcttgcg tactgtcaga
    11701 gcactgattt ctctgacagt acgtgctgcg tgcaaaatca ctacatcaaa taaaccagcc
    11761 aaatctcata gagataagag taaacaaacc aacagcagca aagacattta tcagtactac
    11821 agttctactg gaaacattca tttttgccac cttttatcat tgcccctatg tgtatagtac
    11881 gggttaagaa aatccgcaat aatactcatt ctgaagatgg ataagggcaa gttgctgttt
    11941 gatgattttt tctcaaactg gtgaaaaaaa cttgatgcac gtcaaaaaat gacgcatatt
    12001 tgcgcgcgtt ttattcatct ggctggacgc ccgtacatgt ctctctatca acacatgctt
    12061 gttttctatg cggttatggc agcaatcgca tttcttatca cctggtttct ttctcatgat
    12121 aagaaacgca tccgtctctt aagcgccttt ctggtggggg caacatggcc gatgagtttc
    12181 ccggtggcgc tgttgttttc tctgttttaa atcttatgca ctggcttgac ggcaccacgc
    12241 agacttatat catttggatg aatcgataaa tttcacaagt ggctaaggag aaagtatgtc
    12301 gcatctggat gaagtcatcg cgcgcgtgga tgccgcgatt gaagagagcg tcattgccca
    12361 tatgaacgaa ttattaatcg ccctgagcga tgacgcggag ttaagtcggg aagatcgcta
    12421 caccctgcag cagcgtttgc gcaccgctat tgctcatcac ggtcgcaaac ataaagaaga
    12481 tatggaagcg cgccacgaac agttaaccaa aggcggtacc atcctctgat taaaatgagc
    12541 gtctggccac cagccaggcg ccaaccacaa gtaaaattgc gccacaaatt gggccgatca
    12601 acgcccgaag tggtacgcca tggctgcgga agatatccag caccagaccg ccaatcagct
    12661 ggctggcgac cagtactgca atagttgtcg ccgctcccac attctgatat ccgctgatac
    12721 tggcgaagac aaaaaacgat cccagcaagc caggtataag tgtccaccag cgcacgctgg
    12781 acaccagttc gccaaacccc gccatgcctt gtttaaacca taaaatagaa acaaagagca
    12841 caatccccac cagtgagttc agcaacatgg cgatgagaat ggtagaggag gtctgggtga
    12901 tgcgcaccat cagcgtgttc tggactacca gaccaatccc ggctgcaatc aaaaaggcaa
    12961 gggtaagtga ctgattcatc caatcgcgtc cggttcagtg cgctcgtcga gttgcaactg
    13021 cataaatgtc agatccagcc agcgcccaaa tttagtgcct acctgcggca tttgcgcggt
    13081 gacgacaaat cccagcgact ggtgcagatg cagcgaggcc tgattttgcg attcgatccc
    13141 ggcgaccatg acatgcttcc cgcaatcccg cgcttcatca attaatcggc ttaacaattt
    13201 acgccccaga cctttcccct gatgatcggg atggacataa accgaatgtt ccacggtatg
    13261 gcgaaaacca tcaaaactac gccagtcgcc aaacgaggca tatcccgtca ctacgccatc
    13321 ttcttcactc accagcaccg gataacctgc tatggtccgc gcttcaaacc aggcaatgcg
    13381 gttatccgca tccaccgttt ggtcattcca gatagccgcc gtatacaaca cggcgtggtt
    13441 ataaatttcc gcaattgcag cacagtcggc tttgcgggca aaacggatgg acatgtctgg
    13501 cctcgataaa ataatgatga tgatgttatc aatactatcg aaaacagccc gaagcaacgg
    13561 attcctctat gaaattattg cgtgttgcag aggggatgtg acggctgcaa acaaaaccaa
    13621 tcctgtgagc ctgctactat tgatggattc atgccaaaag cacaggagag cattatgggg
    13681 caacaaacgc agcgtaaccg atgttgggtt ctgtcctcgc gtccgcatgg cgcgccggtt
    13741 ccttacgtct ggtttcggta aatgcgctct ttgtcgcacc agcgcaagca tttacagttc
    13801 cggaagtggg aaaacgtcaa ttaaatgaaa tcaatcggat ccgctacgaa ctggagttaa
    13861 tggcagttgc tctggctgtc gaaaacctca ctatgcaaaa aaacgttgct atgttgtgcc
    13921 agcaatacag ccgataaata aaatacgccc ggcaaatacc gggcttaaag ataattactc
    13981 aaatcgccac gcaatattta tgccgacacc ataatttcgt ccgggcgcag gttcgtaata
    14041 tcgcccgttt gactcattga caatgacaga accaacgtat tctttatcga ataaattatc
    14101 gacacgacca aataaatcca cggttaaatt gtggtaattg tatttatacc cggtgaataa
    14161 gccgacgagt gtataagaag gcgctttggc cgtattttca tcatctgcca taatatcgcc
    14221 catataacgc gcttccgtgc ctgcatacca accatcttcc ggtatataac ctatcgacgc
    14281 aaagcccata ttacgggcga tccctggcat ccggttaccg ttacaatcct gttcattgca
    14341 gacattgctg cgataggtcg catcaagcca ggtccaggac gcttttacgc gaaaatctcc
    14401 cgcgaaacgt tgatcccatg ccagttcagc gccttgacga cgggtctttc cggcattttt
    14461 gtaagtcgta cgcccaccgc tactgctatc gacaacaatt tcatcatcgg tgtcggtctg
    14521 gaacaatgcg agactaagca gtccatcacc aatacgcgtt ttactgccga tctcaattgt
    14581 atcgttggtg gagggtttta aaccaaagtt cataccgctt tgtccatcag cgcgataaga
    14641 cagttcatta atcgtcggcg tttcaaaacc gcgcccggct gccagataga cattccaggc
    14701 atcggtcatt gcatatttta acgatccggc aggtagccat ttgtgataac tggcatcacc
    14761 gctgtcatcg ccgttacccg gagtaacgta atgatcgttg gaatcaaacc acacggagct
    14821 gtagcgcacg ccagcatcca gcgaaagttt gtcggtcagt tgccactggg tttgtaaata
    14881 gggatcgacg ttccacatca aattgcgttc gtcgcggcgc aactcacctt tttgcccgta
    14941 ttccggcacg ccgcgattca ggcggaagtt attgtaaccc ttgcggtttt cactcatgtt
    15001 ttcgtagttc aggccggttg tgaacgtgac tggaacgccc agttcaccac ggtgtgtcca
    15061 gcggctgtct atcccctggt aatggcgttg cagggtaatc acgccgcccg catgtgacgg
    15121 gttaagttgc ggggccatgg ggattgactg gtactgggtc gtttctcgct ctccggcata
    15181 catcatcaca ctcatatcat cttgtgcgct caggctacgc tcatagcgca acccagcctg
    15241 agtttgcttg atggtttttc gcatgtcgta ctgttctgca cgaggcgctt gttgtggatt
    15301 cgccttccat tctgcttcgg ttagcccacc tgggtcatct gctttgatat ccacactatt
    15361 gaaaatcagg cttaatttgc tggcgtcatc aatgcgtacg cccagtttgg cattggctaa
    15421 atttttctgt gcgccactat ggtcacgata gccgtgggtc gtaaaacgtg tggttgcgac
    15481 ggtgtaatcg acatcgccgg gttgtgtgcc gtcgcccgtt gcgcccgttg ctttcagccc
    15541 atagcgccag ctgccaaaac tgccgtagta actactggct tcaatggttg gtggctgttg
    15601 tccggtctgg gtggtgacat tcattacacc gccagacgcg ttgccataca gagcagagaa
    15661 ggggccacgc agcacttcca cattttgcac actgcttaaa tcgatgttag atgtctgccc
    15721 ttgtccgtcg ggcatggtag cgggaatacc gtccacatac aggcgaatac cgcgaattcc
    15781 gtaagtggag cgggagccaa atccgcgaat cgacagctgt aaatcttgcg catagttctg
    15841 tcggttttgt acctgtaaac caggcactcc ggtcagtgat tcagacaagt taatgcgcgg
    15901 tgttgccagg cgcatctcct cgccatccac cacgctcacg gctgctgggg tatccagttc
    15961 tgaaaccacc tgcggtgcgg cactgacaat catggtctgt tcatcagcgg caaaaacaac
    16021 gggggaaagg acaagcagtg cgggcaaaac ggtctgtcgg acggaaaaaa tcttcatgaa
    16081 aaaagccagg ttaagaatgg gaaaacaccg tcatggtaat aaaattgtaa atttatggaa
    16141 aacaaaacgg cacaatacgt taagtaattg agaaaattgt agtcataacg gtaagaaatg
    16201 ctccacattt gagaaaataa tgattaccat tcccatttat aacaagggcg taacgatgat
    16261 tacgcttagc gaagcattgt gaagcagcaa aaatatcggt tcatcaaagg gagtcgtcat
    16321 gcatttacgt catctgtttt catcgcgcct gcgtggttca ttactgttag gttcattgct
    16381 cgttgcttca tcattcagta cgcaggccgc agaagaaatg ctgcgtaaag cggtaggtaa
    16441 aggtgcctac gaaatggctt atagccagca agaaaacgcg ctgtggattg ccacttcgca
    16501 aagccgcaaa ctggataaag gcggcgtggt ttatcgtctt gatccggtta ctctggaagt
    16561 gacgcaggcg atccataacg atctcaagcc gtttggtgcc accatcaata acacgactca
    16621 gacgttgtgg tttggtaaca ccgtaaatag tgcggtcacg gcgatagatg ccaaaacggg
    16681 cgaagtgaaa ggacgtctgg tgctggatga tcgtaagcgc acggaagagg tacgcccgtt
    16741 gcaaccacgt gagctggtag ctgacgatac cacgaacacc gtttacatca gtggtattgg
    16801 taaagagagc gtgatttggg tcgttgatgg cgagaatatc aaactgaaaa ccgccatcca
    16861 gaacaccggt aaaatgagta ccggtctggc gctggatagc aaaggcaaac gtctttacac
    16921 cactaacgct gacggcgaat tgattaccat cgacaccacc gacaataaaa tcctcagccg
    16981 taaaaagctg ctggatgacg gcaaagagca cttctttatc aacatcagcc ttgataccac
    17041 caatcagcgt gcatttatca ccgattctaa agcggcagaa gtgttagtgg tcgatacccg
    17101 taatggcaat attctggcga aggttgcggc accggaatca ctggctgtgc tgtttaaccc
    17161 agcgcgtaat gaagcctacg tgacgcatcg tcaggcaggt aaagtcagtg tgattgacgc
    17221 gaaaagctat aaagtggtga aaacgttcga tacgccgact catccgaaca gtctggcgct
    17281 gtctgccgat ggcaaaacgc tgtatgtcag tgtgaaacaa aaatccacta aacagcagga
    17341 agctacccag ccggacgatg tgattcgtat tgcgctgtaa tagatatggc gagggtgaaa
    17401 acggaaagaa ttgcctgact tttatcacgc cgcatccggc accttcgtca gtagtctgaa
    17461 tttgcccggc acgtagccgg gcaattttgc aattaactcg ccgtttcagg cttaaacaca
    17521 atgtcctgtt tttcttcatc ttcctcgacg actggcgcag tgctgtgaat ttcagcaacg
    17581 cgtttgcgca caccaaacca gcctataacc agcagaatac cgataatcgg cagcgccgcg
    17641 atggtataag tcccgttcgg gtaatcgaac gccatcagca ccaggacact cagtaaaaac
    17701 agtaatgtca gccaggaagt gaagggcgcg ccaggcagtt taaaactgac atccgctgct
    17761 ttgccttctt taatcgcttt acgcaggcgc atctggcaaa cgatgataaa cgcccatgaa
    17821 gcgatgattc ccagcgacgc gaagttcaac acaatctcaa atacgcgtga cggcaccaga
    17881 tagttgagga atacgccgac gacatacaca accagtgtcg ccagaatccc ggcatacggc
    17941 acatgctgac gactcatttt cgccataaaa ctcggtgcgg aaccgcccat cgccatcgag
    18001 cgcagaatac gcccggtgca gtacagacct gaattcaggc tggagagggc agcggtcagc
    18061 accacaatgt tcataatgct gcctatatat ggcacaccca gtttagagaa aaacgtcacg
    18121 aacggacttt gccccgcctg atatgcgctc cacggcaata acataaccag caacaccacg
    18181 gagccgacgt aaaacagacc aatacgccaa atcacactgt taatcgcttt aggtaccatg
    18241 gtctgcggat ctttacattc tccggccgct gtacccacca tttcaatgga ggcaaaagca
    18301 aacactacgc cctgaatcaa caccagcgca ggcagcaaac cgtgggggaa gaagccgcca
    18361 ttatcggtga ttaaatgaaa gccagtggtg ttgccatcca gcggctgacc gctaccgagg
    18421 aacactgtac ccacgaccaa aaaggttaca atggcgagca ctttaataag cgcaaaccag
    18481 aactccatct ccgcaaacca tttcacaccg atcatattca tggtgccaac gatggtcagt
    18541 gcagcgagcg caaagaccca ctgcggcacg ccgccaaacg cgccccagta atgcatatac
    18601 agagcgacgg cggtaatatc aacaatcccc gtcatcgccc agttgatgaa gtacatccag
    18661 ccagcaacat aagcggcctt ctcacccaaa aactcacggg cataagagac aaaactgcca
    18721 ctggaagggc ggtgtaacac cagctcaccc aatgcacgca aaataaaaaa cgaaaacagg
    18781 ccgcagatca aatagaccag tgccagtgcg ggccccgcca tttgcagtcg cgcccccgcg
    18841 cctaaaaaca aacccgtacc aatcgcgccg ccaatggcga tcatctgtac ctggcgattg
    18901 cccatcgctt tgtgataccc ctcttcgtgg gcattaagcc agcggcgttt cgcggcgtgt
    18961 tgatctgaag tgtcggtgtt gtgtttactc attgctctcc ctgattgctt taatgaaaaa
    19021 gtcatataag ttgccatgaa caatgtttat tcatcctggc gatgacaaga ttcaccatta
    19081 ttctttatgg gtataactgt cggcgcagaa tcctaccttt tatcatgtaa cgatgcaaaa
    19141 taatcccgct ataaatatgt ggggataaag tcggctggcg acaaaatagc aacctgatga
    19201 aattatgacg gaaacaacca ctattggttt gatgatacct gactgcagtc ctactcttgc
    19261 gccactcgtt cgtcgctctg aacgccagtg gttgcagtgg acactggcgt ggttggctca
    19321 atgaatagtg aggggctagc acatgatggg tttcaggggt aatacgccaa ataccaatac
    19381 aattgctgat taaatgagcc aattgccgac attacagaaa aggctaaaaa atgtaagagg
    19441 catgtagggt gataaacgcg ctattgccca acaggagttt ctggaattag tcctgttcca
    19501 tgggcattac aactcttaaa acattacttc aatataatta atgtgtatat cattctcaat
    19561 attaatttat gaagtgaatt taatatattc cgaattctta atttacatta ctaatgtatg
    19621 gggcataacg ttaagatggc tatgtgcaga ttaagatatc agggaaagat cacgtaacgc
    19681 tgcttttttg tactaaataa ttcgcatttt atgtttaaaa attgagatat tcctcattac
//
LOCUS       DAPOXO010000093        19445 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPOXO010000093 DAPOXO010000000
VERSION     DAPOXO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19445
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.093"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(47..1401)
                     /locus_tag="ROH59_004058"
                     /pseudo
     CDS             complement(47..1401)
                     /locus_tag="ROH59_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
     gene            complement(1405..1689)
                     /gene="gatB"
                     /locus_tag="ROH59_004059"
     CDS             complement(1405..1689)
                     /gene="gatB"
                     /locus_tag="ROH59_004059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HDX4806477.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQSHNIPVELIQCRVNEI
                     ETYMDGVHLICTTAKVERSFGDIPLVHGMPFVSGVGIEALQNKILTILQG"
     gene            complement(1720..2172)
                     /gene="gatA"
                     /locus_tag="ROH59_004060"
     CDS             complement(1720..2172)
                     /gene="gatA"
                     /locus_tag="ROH59_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HDX4806478.1"
                     /translation="MTNLFVRGGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVLFQQADDDNDVAVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPEPQLKEYFTKYVLDSDE"
     gene            complement(2182..3444)
                     /gene="gatZ"
                     /locus_tag="ROH59_004061"
     CDS             complement(2182..3444)
                     /gene="gatZ"
                     /locus_tag="ROH59_004061"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HDX4806479.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGMTPADFREFVFAIADKVGFARERIILGGDHLGPNCWQQENADAA
                     MEKSVELVKAYVRAGFSKIHLDASMSCADDSIPLAPETVAERAAVLCLAAESVATDCQ
                     REQLNYVIGTEVPVPGGEASAIQSVHITQVEDAANTLRTHQKAFIARGLAEALTRVIA
                     IVVQPGVEFDHSNIIHYQAQEAQALAQWIEKTKMVYEAHSTDYQTQAAYRELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQELIAPENSSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQS
                     GELSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            complement(3473..4327)
                     /gene="gatY"
                     /locus_tag="ROH59_004062"
     CDS             complement(3473..4327)
                     /gene="gatY"
                     /locus_tag="ROH59_004062"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDX4806480.1"
                     /translation="MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAASMHAP
                     VIIAGTPGTFTHAGTENLMALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVM
                     IDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPVQA
                     REFAEATGIDSLAVAIGTAHGMYARAPALDFSRLENIRQWVNLPLVLHGASGLSTKDI
                     QQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIA
                     DCGCEGRA"
     gene            complement(4554..5606)
                     /gene="fbaB"
                     /locus_tag="ROH59_004063"
     CDS             complement(4554..5606)
                     /gene="fbaB"
                     /locus_tag="ROH59_004063"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HDX4806481.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEESSAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            5863..7140
                     /locus_tag="ROH59_004064"
     CDS             5863..7140
                     /locus_tag="ROH59_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806482.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGAVLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVNGLTFNWAGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKVDDRDIALTQGEVK"
     gene            7137..8141
                     /locus_tag="ROH59_004065"
     CDS             7137..8141
                     /locus_tag="ROH59_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HDX4806483.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPDLIGRNILGWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAI
                     "
     gene            8138..9103
                     /locus_tag="ROH59_004066"
     CDS             8138..9103
                     /locus_tag="ROH59_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX4806484.1"
                     /translation="MSGARLHTLLPELTTRQPVMVVGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNREWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEELQDVTPFIDFGPRIGDIPDALLARIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGKQWQEKFAAPLIVRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(9077..9823)
                     /locus_tag="ROH59_004067"
     CDS             complement(9077..9823)
                     /locus_tag="ROH59_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDX4806485.1"
                     /translation="MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQSLEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEDVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(9875..10693)
                     /locus_tag="ROH59_004068"
     CDS             complement(9875..10693)
                     /locus_tag="ROH59_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HDX4806486.1"
                     /translation="MQLRITSRKKFTVLLCALGLISIVAIYPRQTVNFFYSTAIQIKD
                     YIHFYGYRPVKSFAIRIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKAT
                     EGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVSASVQARLFLQTVDFSQGDFPAVL
                     DVEERGKLSAKELRKRVSQWLKMVEKRTGKKPIIYSGAVFYHTNLAGYFNEYPWWVAH
                     YYQRRPDNDGMAWRFWQHSDRGQVDGINGPVDFNVFNGTEEELQGFVDGIKETP"
     gene            complement(10758..11558)
                     /gene="thiD"
                     /locus_tag="ROH59_004069"
     CDS             complement(10758..11558)
                     /gene="thiD"
                     /locus_tag="ROH59_004069"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDX4806487.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAQRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(11555..12343)
                     /gene="thiM"
                     /locus_tag="ROH59_004070"
     CDS             complement(11555..12343)
                     /gene="thiM"
                     /locus_tag="ROH59_004070"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDX4806488.1"
                     /translation="MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTRPRAQAMSAAVEQATRSQTPWTLDPVA
                     VGALDYRRRFCLELLSHKPTAIRGNASEIMASAGVANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEVDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTL
                     ENIASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(12378..12474)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12566..12838)
                     /gene="rcnR"
                     /locus_tag="ROH59_004071"
     CDS             complement(12566..12838)
                     /gene="rcnR"
                     /locus_tag="ROH59_004071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HDX4806489.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            12959..13783
                     /gene="rcnA"
                     /locus_tag="ROH59_004072"
     CDS             12959..13783
                     /gene="rcnA"
                     /locus_tag="ROH59_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HDX4806490.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTA
                     FWMFWRTWRGERNWLENMHEHDHEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHAND
                     IKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGTTLVVSFSLGLA
                     LTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            14002..14340
                     /gene="rcnB"
                     /locus_tag="ROH59_004073"
     CDS             14002..14340
                     /gene="rcnB"
                     /locus_tag="ROH59_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HDX4806491.1"
                     /translation="MTIKNKMLLGALLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAGTHWTYMGGAYVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(14422..15456)
                     /locus_tag="ROH59_004074"
     CDS             complement(14422..15456)
                     /locus_tag="ROH59_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HDX4806492.1"
                     /translation="MEIRIMLFILMMMVMPVSYAACYSELSVQHNLVVQGDFALTQTQ
                     MATYEHNFNDSSCVSTNTITPMSPSDIIVGLYNDTIKLNLHFEWTNKNNITLSNNQTS
                     FTSGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSASSSTRGSAAVQFLLCLLGG
                     KSWDACVNSYRNALAQNAGVYSFNLTLSYNPITTTCKPDDLLITLESIPVSQLPATGN
                     KTTINSKKGDIILRCKNLLGQQNQTSRKMQVYLSSSDLLTNSNTILKGAEDNGVGFIL
                     ESNGTPVTLLNITNSSKGYTNLKEIAAKSKLTDTTVSIPITASYYVYDTNKVKSGALE
                     ATALINVKYD"
     gene            complement(15472..17952)
                     /locus_tag="ROH59_004075"
     CDS             complement(15472..17952)
                     /locus_tag="ROH59_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX4806493.1"
                     /translation="MLRMTPLASAIVALLIGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREMIKRLGINTDNFASGK
                     QCLTFKQLIQGGSYTWDIGVFRLDFSVPQAWVEELEIGYVPPENWERGINAFYTSYYM
                     SQYYSDYKASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFSGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDFAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGTGW
                     NTRFGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDNYRRDENDIYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNLRRISYTLAASHAYDENHHEEKRFNIFISIPFDWGDDV
                     TTPRRQIYMSNSTTFDDQGVASNNTGLSGTVGSRDQFNYGVNLSYQYQGNETTAGANL
                     TWNAPVATVNGSYSQSSAYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVVYDGMTPYRENYLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQPLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVN
                     VAIDKQQGLSCTITFGKEIDESKNYICQ"
     gene            complement(17968..18642)
                     /locus_tag="ROH59_004076"
     CDS             complement(17968..18642)
                     /locus_tag="ROH59_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDX4806494.1"
                     /translation="MKGLLALLISSMVLPAHAGIVIYGTRIIYPAEHKEVMVQLMNQG
                     NRSSLMQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGN
                     YISDKI"
     gene            complement(18723..19265)
                     /locus_tag="ROH59_004077"
     CDS             complement(18723..19265)
                     /locus_tag="ROH59_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX4806495.1"
                     /translation="MKRSIIAAAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFE
                     AGGDSVSINMPTVPTTVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNDK
                     ITGNDKAIASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKIADGQYAIPFKAKYLKLT
                     DNSVNSGDVLSSLVMRVAQD"
BASE COUNT         4910 a         4940 c         4472 g         5123 t
ORIGIN      
        1 aaaactcctg attgttaagg gggataacct ccccctcagg taaaaattat tctgcgagaa
       61 cggctttctc ttgtttaata aaaccacgcg ctctacgcca ggtcatgaaa ataccggtaa
      121 gataaattgc gccgataaca atgaaaccgg gaatattttg cggggagaaa acctgaatca
      181 gtaaccaggt aatgggagaa ccgccctgat ccattgaagc caccataccc ccggctttta
      241 acgcgcccgc attagccgcc agttgggtgt gcaaaccaat agtttgcgtc gcgatccaca
      301 gggtgatgct cataatgatg acacccgaga ttaaggtgcg gaacagattt ccacgatgca
      361 ccgcgaccgc catcgccaca aagaagccga tggtggcaag gtcgccaaac ggcagcacct
      421 gattacccgg cacacaaaca gcaattaaaa tggtgagtgg aataaaaatc aggcttgccg
      481 ataccaccgc cgtatgtccc agcagcaacg ccggatcaag gccaatcagg aactcctgac
      541 cgccgaactt cgcctgtaaa cgactacggg cctgcttagc gatgggcgtt aaaccatcca
      601 tgatgggttt aatcacccgt ggcatcagca gcataactgc cgccgttttt accgccagct
      661 gcaatacacc tttgacatcg taacccgcga ggatgccgat aatcagcccc atcacaaaac
      721 ccacggtgac cggttcgcca aaagggccaa atttgcgctg aatatcatcg gcgctaaatt
      781 taattcggtt aacgcctggg atttctcgat gatagcatcg accagcacag caattggccc
      841 catatacgcc gacgtaccgt gcggaatagc aatgccttcc agctcaaaga aatcacgggt
      901 atcgcgggca aaccagtcgc cgagcttata aacaaacgcc gcgtgaatta ccacacccgc
      961 catccctatc atccatgaac cggttgccag atgcagcaac gcgccggtga aggtcatatg
     1021 ccagatattc cagatatcaa catttaccac ccgcgtcata cgggtcagta acatcgccac
     1081 gttaaccaga atcgcaatcg gaatcgccac cagcgcaatt tgcgacgccc aggtcatggg
     1141 tgaagagccc ggccagccga catcgaccac atgcagattc aggtcgaaat tttccgccat
     1201 cgctttcgcc gccgggccaa tggaatccag cattaagcca atcacaaggc caatgccaac
     1261 aaagccaatc ccgatatgca gacccgcttt aaagcaatcg cctgccttca tgcctaatat
     1321 tttagaaaaa ataatgatga caatcggcag catcaccgta gggccgaggt cgagaatata
     1381 acgcatgact tctgaaaaca taggtcaccc ctgtaagata gtcagaattt tattttgtaa
     1441 tgcttcgata ccgacaccag aaacaaaagg catgccgtga actaacggaa tatcgccaaa
     1501 actgcgttca actttggcgg tagtacatat caaatgcacg ccatccatat aggtttctat
     1561 ttcattaacc cgacactgga ttaattcaac aggaatatta tgactctgac acaactcttt
     1621 aatttcttcc gccgccatcg tagaggtcgc taccgcgcct ccgcaagcga caataatttt
     1681 gcgtttcata aatagtcctt tttattgtta cagagggatt tattcgtctg aatctaaaac
     1741 atactttgtg aagtattcct ttaactgggg ttcaggaaga gtgattagtg tctcgacgat
     1801 atcgggctgt tgtaacttgc caaataaaca gcgtaaaagt ttcaattgct gctgcggatt
     1861 ttccacaatc aacgcaataa ccaacgatac cgccacgtcg ttatcatcat ccgcttgctg
     1921 aaaaagaact ttatttgttg gccttaacag ataaatggct gacgacttag catgaatcgc
     1981 ctcacaatgc ggtattgcaa tggcgtgctg ctcaagcatt atcccggtag ggaattctgc
     2041 ttctctggca attaatgcct gtggccaggt atcatgaacc acacctttcg cgagcatctc
     2101 attaccgata tgggttaaaa cttcgctacg atcgacaaaa gaaattccgc cacgaacaaa
     2161 caggttagtc atataccgtc cttattccgc acagccgtag cgataggcgc gcaaaacatc
     2221 ataaatttta tccataataa gctgatgcgg tattgctgat aattccccgg actgaatgcg
     2281 ttcaaattgt ttcggaagat actgactaat catgcccagt gggatgtcta cgccttccag
     2341 attcaccatc atcgtttcga cgctattttt aatccggcta tgcggccagt aataacgaat
     2401 acgatccgac aggctgtaac gaatatccag taatgaatcg ttaaaacccg tgcgataata
     2461 tttcttccag tactgcggtt cgtcgagcat cacttcttca attaccgcca ggcaaccact
     2521 gctattttcg ggggcgataa gttcctgctc aatttgcgcc agcgcaaata tcgcctcgcg
     2581 taacgcaaag gttaatgccg gaccgacttt caaaattgca aaatgatcgc gaactaattc
     2641 ccgataggcc gcctgagtct ggtaatcggt ggaatgcgct tcataaacca ttttggtttt
     2701 ttctatccat tgcgccaacg cctgagcttc ttgcgcctga taatgaataa tattgctatg
     2761 gtcaaattcc acaccaggct gcaccacgat ggcaatcacg cgtgttaacg cctctgccag
     2821 accgcgggca ataaacgctt tttgatgcgt gcgtaaagta ttggcggcat cttcaacctg
     2881 ggtgatgtgt actgactgaa tggcgctggc ctcaccgccc gggaccggaa cttcagtgcc
     2941 aatgacatag ttcagttgct cacgctggca atcagtcgcc acactttccg ccgccagaca
     3001 aagcacagcg gcacgttcag caaccgtttc tggcgctaac ggtatggaat cgtcagcgca
     3061 ggacattgac gcatcaagat gaattttact gaagccggca cgaacatatg cctttaccag
     3121 ctcgacggat ttttccatcg ccgcatccgc attttcttgc tgccagcagt ttggtcccag
     3181 atggtcgccg ccgagaataa tacgctcacg agcaaatccg actttatcgg caatagcaaa
     3241 aacaaattcg cgaaagtctg ccggtgtcat tccggtataa ccgccaaatt gattgacctg
     3301 gtttgacgtt gcttcaatca gcactttacg cgtgctgttg cgatcaaatg ccagcgccgc
     3361 ttcgataacc aacggatgtg cagaacagac tgaacatatg ccaatatgtt caccagcttt
     3421 atgccgggca attaacgttt tcatgttttt tccttgttaa atggcaggtg cgttatgccc
     3481 tgccctcgca gccacaatcg gcaatcactt tgctcaccac atcgcgcatt gcagatttag
     3541 ccgactgcaa ataatcacgg ggatcggtcg cttcggggtg ctcggtcagg taatttttta
     3601 acgcctgcga gaaggcattt ttcagctccg ttgcaacgtt gattttgcat atccccagtt
     3661 tgatggtttg ctgaatatcc ttagtcgata atcctgacgc gccatgcagc accagcggta
     3721 aattcaccca ctggcgaatg ttctccagtc gagaaaaatc aagcgccggt gctctggcat
     3781 acataccgtg agccgtgccg atggcgaccg ccagggaatc aatcccggtt gcctcggcaa
     3841 attcacgcgc ctgaacgggg ttggtgtaca acgcatctgc ttcattgact tgcacatcat
     3901 cttcctggcc gccaagttgc cccagctccg cttcgacgct gacatcaaag cgatggcaaa
     3961 aatccaccac ctctttgacc cgtgaaatat tttgcgcaaa aggcaaatgc gaggcgtcaa
     4021 tcatgactga gcgcacgcca gaacgaacct tctgagcgat atcgtcaaat tttgtgtgat
     4081 ggtcgagatg aatcgccagt ggatggtgat attgcttcgc catcgcgctg accagcgcca
     4141 tcagattttc tgtaccggca tgagtaaatg tgccgggcgt tccggcgatg atgaccggcg
     4201 catgcatgct ggcagcggtt tccaccacca cttgcatcgt ttcgagattg tgaatattga
     4261 atgccggaac cgcataaccg ccgcgctgcg cgttgttcag catctgcttt gtcgatacca
     4321 cgtacatttt cacatcctgt catttgtttt cgatttcaaa atataatgaa attatttgtt
     4381 ttcaaatgtc gagataacga tcacaaaaac gacaatgtga aaattaatca gaatgacagg
     4441 caaaaaaaac ggcctcccgg gggaagccgt aacgaagtgc gcgtgttttt atgccggatg
     4501 caacgtaaac gccttttccg tcctacgggg tggttctgtt cgtatgaggc gcatcaggcg
     4561 atagtaattt tactatcgag ataaacgtcc tgtacggcgt taatcagttt cacgccgtca
     4621 gccatcgatt tcttgaacgc cttacgtcca agaatcagcc ccattccgcc tgcgcgtttg
     4681 ttgataaccg cagtacgcac tgcatcgctg aggtcagttt caccgcctgc agcaccgccg
     4741 gagtttatca acccggcccg gcccatatag cagttagcta actgataacg caccaggtca
     4801 atcgggtttt cactggtcag tttgctgtag actcgatcgt cggtataacc gtaattaatc
     4861 gctttatagc cgccgttatt ttccgccatt ttttgtttga cgatatctgc acctatggtt
     4921 gccgccagat ggttcgcctg accggtcagg tcggcggaaa catggtaatc aacgccatct
     4981 ttcttaaagg cggagttacg caaataggcc cacagcactg tcaccatgcc cagctcgtgc
     5041 gcacgttcaa aagccgcaga actttcttca atctggcgac gtgactcttc cgagccaaaa
     5101 tagatagtcg caccaaccgc caccgcgccc atgttgaacg cctgctccac gctggcatac
     5161 agcgtttgat cgtaggtatt cgggtaactt agcgtctcgt tgtgattaag tttgacgagg
     5221 aatggaatgc gatgcgcgta acgccgcgat accgatgcca gcacgccgta agttgacgcc
     5281 acacagttac agcccgcttc gatcgccagt tcaacaatgt ttttcgggtc aaagtagagc
     5341 gggttagcgg caaatgaagc tccggcagag tgctcaacgc cctggtcaac cggcagaata
     5401 gaaagatatc ctgtgccagc cagacgcccg gtgttgtaca acgtctgcat attacgtaac
     5461 accgctggcg ggcgattatt gtcaatcatc acgcggtcta cgtagtcatg tccggggaga
     5521 taaagctggt cagaaggaat agtcatacaa cggtgctgta aaaggttgtc ggcgtctttg
     5581 ccaagcaact gcgcaatatc tgtcattact atgctcccgt aaattccgat tggatatcgg
     5641 ctatggattg tcctggcccg ccttttgcgg gcaatcataa tcctggtcgt tacgggcgag
     5701 tttttccatc ttttggatgt tttttcagcg ttttctgttg gctcgattca tcagaaaaaa
     5761 tgttaccgcg gtcaagtttt caccgcaaag gtatttaaaa ggtattacta agtggtattg
     5821 tcatcgcgta ccttacatta cctgtcatga aggaattaaa agatgaaaac aacagcaaag
     5881 ctgtcgttca tgatgtttgt tgaatggttt atctggggcg cgtggtttgt gccattgtgg
     5941 ttgtggttaa gtaaaagcgg ttttagtgcc ggagaaattg gctggtcgta tgcctgtacc
     6001 gccattgcgg cgatcctgtc gccaattctg gttggctcca tcactgaccg ctttttctcg
     6061 gcgcagaaag tgctggcggt attgatgttc gctggcgcgg tactgatgta tttcgctgcg
     6121 caacagacca cttttgccgg gttcttcccg ttactgctgg cctactcgct aacctatatg
     6181 ccgaccattg cgctgactaa cagtatcgct tttgccaacg tgccggatgt ggagcgtgat
     6241 ttcccacgca ttcgtgtgat gggcactatc ggctggattg cctctggtct ggcatgtgga
     6301 ttcttgccgc aaatgctggg ttatgccgat atctcaccga ctaacatccc gctactgatt
     6361 accgccggaa gttctgctct gctcggtgtg tttgcgtttt tcctgcccga cacgccgcca
     6421 aaaagcaccg gcaaaatgga tattaaagtc atgctcggcc tggatgcgct gatcctgctg
     6481 cgcgataaaa acttcctcgt ctttttcttc tgttcattcc tgtttgcgat gccactggcg
     6541 ttctattaca tctttgccaa cggttatctg accgaagttg gcatgaaaaa cgccactggc
     6601 tggatgacgc tcggccagtt ctctgaaatc ttctttatgc tggcattgcc gtttttcact
     6661 aaacgctttg gtatcaaaaa ggtattgttg cttggtctgg tcaccgctgc gatccgctat
     6721 ggcttcttta tttacggtag tgcggatgaa tatttcacct acgcgttact gttcctcggt
     6781 attttgctgc acggcgtaag ttacgatttt tactacgtta ccgcttacat ctatgtcgat
     6841 aaaaaagctc ccgtgcatat gcgtaccgcc gcgcaggggc tgatcacgct ctgctgccag
     6901 ggcttcggca gtttgctcgg ctatcgtctt ggcggtgtga tgatggaaaa gatgttcgct
     6961 tatcaggaac cggtaaacgg actgactttc aactgggccg ggatgtggac tttcggcgcg
     7021 gtgatgattg ccattatcgc cgtgctgttc atgatttttt tccgcgaatc cgacaacgaa
     7081 attacggcta tcaaggtcga tgatcgcgat attgcgttga cacaagggga agttaaatga
     7141 aaacagaacg tattctcggt gctctttatg ggcaggcgtt aggggatgcg atggggatgc
     7201 cctccgagct ttggccgcgc agtcgcgtca aagcacactt tggctggatt gaccgttttc
     7261 tgcctgggcc aaaggagaat aacgcggcct gttattttaa ccgcgccgaa ttcaccgacg
     7321 atacctcgat ggcgctgtgt ctggcggatg cgttactgga acgtgaaggc aagatcgatc
     7381 cggatctgat tgggcgtaat attctcggct gggcgctgcg tttcgacgcc tttaacaaaa
     7441 acgtactagg tccgacctcg aagattgcgc ttaacgccat tcgcgacggt aaacccgttg
     7501 ctgaactgga aaataacggc gtgaccaacg gcgcagcgat gcgcgtctcg ccattaggtt
     7561 gtttgcttcc ggcgcgcgat gttgattcct ttattgatga tgtggcgctg gcctccagcc
     7621 cgacccataa atccgatctg gcggttgcgg gggcggtagt catcgcatgg gcgatttctc
     7681 gtgccattga cggagaaagc tggtcagcga ttgttgattc actgccttca attgcgcgac
     7741 atgctcaaca aaaacgcatc actaccttca gcgcctcact ggcagcacgt ctggagattg
     7801 cgctgaaaat tgtgcgcaat gccgatggca ccgaatccgc cagcgaacag ctttaccagg
     7861 tcgttggcgc aggtaccagt actattgagt ccgttccgtg cgccattgcg ctggttgaac
     7921 tggcacaaac cgacccgaac cgttgcgccg tcctgtgcgc taaccttggc ggcgacacag
     7981 acaccatcgg tgctatggcg acggcaattt gcggcgcgtt gcatggcgtt aacgctatcg
     8041 atcctgcgtt aaaggcggaa ctggatgcag taaatcagct tgatttcaac cgctatgcca
     8101 cagcgctggc gaaatatcgt caacaacggg aggcgatatg agcggcgctc gattacacac
     8161 gctgctgcct gaattaacca cgcgtcagcc agtgatggtc gtcggcgcgg cggtcattga
     8221 tgtgatcgcc gacgcttacg ctctgccctg gcgtgggtgc gatatcgaac tgaaacagca
     8281 gagcgttaac gttggcggct gcgcactgaa tattgccgtg gcgttaaagc gcctcggcat
     8341 cgaagcgggt aatgccctgc cgctcggtca gggcgtgtgg gcggagatta ttcgcaaccg
     8401 gatggcgaaa gaggggttaa tcagcctgat cgataacgct gaaggcgata acggctggtg
     8461 tctggcgctg gttgagccgg atggcgaacg cacttttatg tcattcagtg gtgtggaaaa
     8521 tcagtggaat cgcgaatggc tggcgcgatt aaccgttgcg cctggcagcc tgctctattt
     8581 ttccggttat caactggcct cgccctgcgg cgaattgtta gtggaatggc tggaagagct
     8641 gcaagacgtg acgccattta tcgattttgg cccacgtatt ggcgatatcc cggatgcatt
     8701 actggcgcgg atcatggcct gtcgaccttt agtgtcactc aatcgtcaag aggctgagat
     8761 tgccgccgaa cgttttgctt tatccgcaga gataacaaca cttggcaagc aatggcagga
     8821 gaaatttgcc gcgccgttga tcgttcgtct cgataaagag ggcgcatggt atttcagcaa
     8881 cgacgcttct ggctgcattc cggcatttcc aacgcaagtt gtagacacca ttggggcggg
     8941 cgacagtcat gccggcggcg tacttgccgg gctggcctct ggtctgccac tggcggatgc
     9001 cgtattactg ggcaatgcag tggcgtcgtg ggttgtcggg catcggggcg gtgattgtgc
     9061 gccaacgcgc gaggaactac tcctcgcaca caaaaacgta tagatcgctg cgacagtggc
     9121 tgatgctgta ctcaataggc cgttgctgtt ggtcaagcgc cacttgcttg atcaccagca
     9181 ccggtatttt gctatctaac tgaatatgtg actgaaactc ggcatccggc atccgggcgc
     9241 taacgcggga acgcgtacgt tgtgggtaaa tgtgctggct gcggaagtag tcataaagag
     9301 aaatcccgat ggcatcaaca tcatgaatta aatgtgccgg aacccacgat tcctcaatcg
     9361 ataccgcctc ttcatcgaca tagcgaatac gcttaagcaa aaaaacatca cttcctgcct
     9421 cgaccgccag ctgctgcgcg acgtcttcgg gacatttcac gacacgcttg ttaacccata
     9481 gcgtatcggg ctttttcccg cgcaacacca cctgctgaga aaaacctcgc gcttctttca
     9541 acgagtattc gaagatgttg ttgatctgcg tgccgtaacc acgcgaacgc gtcaccacgc
     9601 cctcttcttc cagcgactgc atcgccttgc gcaccgtaat gcgcgaaacg ccggttaact
     9661 gacttaaatc acgctcaccg ggcaaaatat tgccatgctc cagcaccccg ctgcgcacgg
     9721 cattttttac cgtttcggca aacttaatat aaagcggcgt gttatccgcc gctaaaatac
     9781 gctcgttcag ttgggcaatc agctgggtat gcgcttgttc catttgtctt tttcctgccg
     9841 gggaatctgg tgggagtata tcactgcttc ttatttaagg cgtttcttta atcccatcaa
     9901 cgaatccctg caactcctcc tctgtgccat taaacacatt aaaatccacc ggaccattaa
     9961 tgccatcgac ctgtccacgg tcggaatgct gccagaagcg ccaggccatg ccgtcattgt
    10021 ccgggcgacg ttgataatag tgagccaccc accacggata ttcattgaaa tagcccgcca
    10081 gattggtgtg ataaaaaacg gctcctgagt aaataatcgg cttttttccc gtacgttttt
    10141 cgaccatttt tagccactga cttacccgct tgcgtaattc ttttgccgat aattttcctc
    10201 gctcttctac gtccagtacc gcagggaaat cgccttgtga gaaatccacc gtttgcagaa
    10261 ataatcgcgc ctgaactgaa gcggatactg acggggagaa ataatgatac gccccgcgca
    10321 gcaggccatt ttcccggctt agttgccagt tacgcgaaaa ataggggtcc accagctttt
    10381 cgccttccgt cgccttaata aaagcaaact gtaagcggat accgttgtcg cgcatttttg
    10441 ccacccgctg ccagtcgatc cgctcctgcc agcgcgaaac atctattccg tgaatggtgt
    10501 aactggcagg aatgcgaata gcgaaagatt taaccgggcg ataaccgtag aagtggatgt
    10561 agtctttaat ctgaattgct gtcgaataga aaaaattcac cgtctgacgc ggataaattg
    10621 caacgatgga aattagccca agagcgcata ataaaacggt gaattttttt cgactggtga
    10681 ttctcaactg cattggtttc atccctgaat gtcagcacca aaggctgaca ataaccaaag
    10741 cagctatagt acggtgctca ccaccaggcg tggaagtggt gaaccggacc aataccgtga
    10801 ccaacttcca gcgtgtcggc ctgggctaat gccgatgaaa gccagctttt tgcctcctgt
    10861 acggtgtcag cccagtttgt atggcgcggg cgcagtgcag ccaacgccgc agagagcgta
    10921 caaccagtgc cgtgagtgtt tttggtcata atgcgctgtg cggtaaaccg ttgttcaccc
    10981 tcgcgggtaa acagccagtc cgggctttgc tcatcatcca gatgaccacc tttcattagc
    11041 actgcgccac agcccatcgc caacagcgat cgcccttgtt ccagcatttc ctgttcggtg
    11101 cgcgcgtgtg gcgcgtcgag caaggcggct gcttcgggca agtttggcgt tattaatgaa
    11161 acctgtggca ataatcgact gcgtagcgtg gcaactgccg aaggtgaaag cagcgggtcg
    11221 ccgctttttg ccagcataac ggtgtcgagt accacgtttt ggatctgata acgttgcaac
    11281 cgttctgcca ccgcttcaac aatatcggtt tccgccaaca taccgatttt agtggtgtcg
    11341 attcgcacat cgctgaacac cgaatcgagc tgggcggcga caaaatcagg ctcaatgcga
    11401 tacaccgact gtacaccacg ggtattttgc gccaccagtg cagtaataac tgagcaacca
    11461 taagcgccaa gtgccgagaa ggttttaaga tcggcctgaa tccccgcacc accactcgga
    11521 tcagtaccgg caatcgtcag agcgttaatt cgtttcatgc ctgcacctcc tgcgtcaatt
    11581 gccagagcgc atcaaggaaa tgtggaacaa aactgcctgg cccctcgctt ctggcgactg
    11641 cgcgttctcc ggcttgtttc atccagtgac aggcagatgc gatattttcc agcgtatcgc
    11701 ctggtagcgc acaacaggca gcgacaaccg ccgatagtgc acagccagtt cctaccactt
    11761 tggtcattaa cggatcgcca ccgtgaatgc caatgatacg atgtccatcg gtaacataat
    11821 ccacctcgcc agtgaccacg acgattgcgc cagtttcccg tgccagtgtt tgtgcagcag
    11881 gtatcgcgtt agctgcggca tcagtggtat ccactccccg tccaccatta gcaacgccag
    11941 ctgatgccat gatttccgaa gcattaccac gtatggcggt tggcttatgg gacagaagtt
    12001 ccagacaaaa acggcggcga taatcgagcg caccaaccgc aaccggatca agcgtccagg
    12061 gcgtttgtga tcgtgttgct tgctcaacgg cagcactcat cgcttgcgct cgtggccgcg
    12121 tcagcgtgcc aacgttaatc aacaaggcac tggcgatagc cgcaaactga ctggcctctt
    12181 cggtttcgat aaccatcgct ggcgatgcgc cgagcgccag caaggtattg gcagtaaaag
    12241 tttgcaccac atcgttggtc atgcagtgca caagagggga atgttggtga aaaaggtgta
    12301 acgcgtgcgc agattgcgct gaactcagca ggtcgacttg catagtttgc tcctgccata
    12361 acgtgaagaa gcaatgacct ggtggtccgt gacttcccta cgctggcatt atccagatca
    12421 ggtgatacgg gtatttctca gccttcacaa agaagggcac cccgagtcgt ttggttgcga
    12481 taataaatcg cagaggagga tggtaatgtc cagcgcacgc gttgtaaacg gggaaaaacg
    12541 gcggtattac aataacgttg tgaaattatt tgatataaga atccagcacc ttcagaacga
    12601 catccagatc ttcttcacgt tttagctcat ccccctggtg aacgatgtgt tccgtcagat
    12661 ggcctttaat cacttcccgc atcagaccgt ttaccgcgcc acggatagca gcaatctgtt
    12721 gtaaaactgc agcgcattca tgcggttcgt cgagcatttt cttgagcgcc acgacctggc
    12781 cctgaatctt actggcacgc gctttcagtt tctgtttatc acggattgta tgagacatgg
    12841 caacacctgg ttaacaagaa tatgaaaaat catagcacta ttaatctact ggggggtagt
    12901 atcaggtact gggggggagt agaatcagat tgccgaatta atactaagaa ttattatcat
    12961 gaccgaattt acaacacttc ttcagcaagg aaacgcctgg ttcttcatcc ccagcgccat
    13021 cttacttggt gcgcttcatg gtctggaacc ggggcactca aaaacgatga tggcggcgtt
    13081 tatcatcgcc atcaaaggca ccattaaaca ggcggtgatg ctcggactgg cagcaactat
    13141 ttcgcatacc gcagtggtct ggttaattgc ctttggcggg atggtgatca gcaaacgctt
    13201 tactgctcaa tcagcagaac cgtggctcca gttgatttcc gcagtgatca ttattagcac
    13261 cgcgttctgg atgttctggc gtacctggcg cggcgaacgc aactggctgg agaatatgca
    13321 cgagcatgat catgagcatc atcaccacga tcacgaagat caccacgacc atggacatca
    13381 tcaccatcac gaacatggcg agtatcagga tgcccatgca cgagcccatg ccaatgacat
    13441 taaacgacgc tttgatggta gagaggtcac caactggcaa attttgctat ttggcttaac
    13501 cggtggcctt atcccctgcc cggcagcaat taccgtgctg ttgatttgca ttcagttgaa
    13561 agccctgaca ctgggcacaa cactggtcgt cagtttcagc ctcggcctgg cgttaacgct
    13621 tgtcaccgta ggcgttggcg cagcaatcag cgttcagcag gtcgcaaaac gctggagcgg
    13681 atttaacact ctcgctaaac gcgctcccta tttttccagt ctgttgattg gcttagttgg
    13741 tgtgtatatg ggcgtacatg gcttcatggg cataatgcga taactcaatc ctttaggctt
    13801 gcatgttatc ttcagcccag gatgattctt aaatcagcta tttccgctga ctctctgctc
    13861 gctaaggatg cttttagggc atcctttcat ttacactttt tacgaaatca tgggatcact
    13921 aacaaaatat cgcttgtcag ttatattgta tggcaggaaa gatatgcgac tgatattaca
    13981 gatccccaaa gtggagagtt tatgaccatt aaaaataaga tgttgctggg tgcgcttttg
    14041 ctggttacca gtgccgcctg ggccgcacca gccaccgcgg gttcgaccaa tacctcggga
    14101 atttctaagt atgagttaag cagtttcatt gctgacttta agcatttcaa accaggtgac
    14161 accgtcccag agatgtaccg caccgatgag tacaacatta agcagtggca gttacgtaac
    14221 ctgcccgcgc ctgatgccgg gacgcactgg acctatatgg gtggcgcgta cgtgttgatc
    14281 agcgacaccg acggtaaaat cattaaagcc tacgacggtg agatttttta tcatcgctaa
    14341 aaaaaagccc cctcggagag aggggggaat gcagacacct taatattttt attattagcc
    14401 acttgctcgt cttgcttgtt attagtcgta tttcacgttg attaatgcgg ttgcctccag
    14461 tgcgccagat ttaactttgt ttgtatcgta gacgtagtaa ctggccgtta tcggaattga
    14521 aaccgttgta tctgtaagtt ttgactttgc cgcaatttct tttaaatttg tatatccttt
    14581 actgctgtta gtgatattta aaagtgtgac tggcgtacca ttactttcaa gaataaatcc
    14641 tacgccatta tcttccgcac ctttcaggat cgtgttgctg ttggttaaca agtcagaact
    14701 tgataaatac acctgcattt tccgtgatgt ttgattttgt tgacctaata aatttttaca
    14761 acgcagaata atatcccctt ttttactatt tattgttgtt ttgttacctg tggctggtaa
    14821 ttgtgaaacg ggaatactct ctaacgtaat taataaatcg tccggtttgc aggttgtggt
    14881 tatcgggttg tatgacaatg tcagattaaa ggaatagaca cctgcatttt gtgccaatgc
    14941 atttctgtag ctatttacac atgcatccca tgacttacca cctaataaac acagtagaaa
    15001 ttgtactgcg gcactcccac gtgtcgatga tgaagcactg gataatgtcg caactccatt
    15061 aatcatcact gaaccaccgc cccccgcaga aacattcact tttgcattac tggccgcagg
    15121 tgtcaccgtt accgaataac cactggtgaa actggtctga ttatttgaca atgtaatgtt
    15181 gtttttattt gtccattcaa aatgtaaatt taatttaatg gtatcgttat aaagtccaac
    15241 aataatatcc gacgggctca taggggtgat agtatttgta ctcacgcatg acgaatcatt
    15301 aaaattatgc tcatatgtcg ccatttgtgt ttgagtaagt gcaaaatccc cctgaacaac
    15361 caaattgtgc tgaacagata actcactata acatgccgca tagctcacag gcataaccat
    15421 catcattaat ataaatagca ttatgcgaat ttccatagaa ccacctgact attactggca
    15481 aatataattt ttactttcat caatctcttt accgaaggtg attgtgcatg aaagcccttg
    15541 ttgcttatca attgccacat taaccgatgg cggtacttca ttggtgcgaa taaataactg
    15601 gcttccctgg ccgacaacac caatattatg accatggata tcattgactt cataaccaaa
    15661 cgttaatggt tgcccatccg ctcttaatgc ttttataaac catggcttgc gctgatcggt
    15721 atcaaaatta accagtacaa ccgcgccgcg ataaggggcg gcaattttcc ggttgccacg
    15781 taattctgct tcgctatcgc tttgtgacac atccaacatc aggtaatttt cccgataagg
    15841 tgtcattccg tcgtatacca ccactccatt acggtttgtt gtgcgatatt tttgcccatt
    15901 gacataagca tctttaattc ctggcgcatt catcacagca aacgtttcag aaagacggtt
    15961 tgccagatta acgccacccg accaggcgac aatgccccct gaaacactgg ctccagcctg
    16021 tcgataagca ctcgactgac tataactgcc attcactgtc gcaaccggcg cgttccaggt
    16081 taaattcgcc ccagctgtcg tttcatttcc ctgatactga taactcaggt tgaccccata
    16141 gttaaactga tcccggcttc caacggttcc tgataatccc gtattatttg aggcaacccc
    16201 ctgatcatca aacgtcgttg agttagacat atatatttgc cgacgaggcg tcgtaacgtc
    16261 atcaccccaa tcaaagggaa tcgatataaa aatattaaaa cgtttctctt catgatgatt
    16321 ctcgtcataa gcatggcttg ccgcgagggt atagcttatc cttcgcaggt tgttggaata
    16381 actcaactga taatccttac tgctgccgct acgcccccag taatctcgcc ataacgtact
    16441 taaggacaca gaaccccagc cttctggcaa tgactgactc atattggcag aaaagctatt
    16501 tttacggcca aaatcgttct ggtaataatc ggcaatgtca tagatatcgt tttcatcacg
    16561 gcgataatta tctttattgt ttgcccatac gtgatcatta aatgtccgat aatcacgcga
    16621 cgaataacgc caggccgcca gaccaaaacg tgtcgacgtt tggctcacaa atttgttgta
    16681 ggcaatttga taactttgcc cgtcaaacac atcgccgttg tcttgtttac tatgcgactt
    16741 tgtggcatcg acggaaatgg caccaaagcg tgtattccag ccagtcccca aagtgaacgc
    16801 gtaataatta ttcgcgacca tcgagccacc atacagcgtt aataagttat taaaaccata
    16861 ctgataaccc gcctggacaa aatcactttg tttgctcgcc ccttcaatat ggctacgacc
    16921 cgccgcaaaa tcatatttcg acacgccggg ttgcagcata tttggtaccg ctgcataagg
    16981 caccagatag gtggttaccg aaccgtccgc ctctttcacg ctaacatcaa gatccgctcc
    17041 accaccggcc aactgcaaat ctgtaatcgc aaacgggcct ggaggaacct ctttctgata
    17101 aaccacaaaa ccattctgtt caatagttac cagcgcgtta ctctgagcaa tcccctgcac
    17161 tcgtggcgta aaattttgtt tcgagttagg caacatctgc atatcacgaa acaaccgcac
    17221 accgctgaag cgaacagaat caaaaatatc gcttgatgtg tacatatcac ccacacgaag
    17281 cgtgccgaga agttgggcaa atccacgttc cagatacagg gtattgctct tccacacccc
    17341 tggattgtta tttgttttac tgaaactggc atcagaatgc agttgccacc ccaataaatt
    17401 taacccgctg ttaaaacgta catatgtact cttgctatta ccggacgctt tataatcgct
    17461 gtaatactga ctcatataat aagaggtata aaacgcatta ataccccgct cccagttttc
    17521 aggtggtaca tagccaattt ccagttcttc cacccaggct tgcgggacac tgaaatcgag
    17581 acgaaaaact ccgatatccc aggtatagct cccgccctga ataagttgct taaatgttaa
    17641 acattgctta ccgctggcaa agttatcggt attaatgcct aaccgcttga tcatttccct
    17701 tgataaacat gtttcttgcg ggttgtcttt aacaatgatc tcatatttcc cacgccattg
    17761 cttattgaca taaatatcga tgtcatactg ccccggcaag ggttgattat catcaagacg
    17821 aatatttgca acctgctggt ctttcattcc acctatcatg aaatgggtat caaaggtttc
    17881 ttcagctgca taagcttcaa tgccgatcaa taacgctacg attgctgatg caagtggggt
    17941 cattctcaac ataggcagct cctgcaatta aattttgtca ctaatatagt tgccatggtc
    18001 atcgataatg gtcagatgcc agttatttgc attattactt ttgacattaa cactctgact
    18061 ttctaagggg gcaatcataa tagtttcata attgactttg acattattag ctttgacatc
    18121 cgaaatcgtc acccaattag ctgagtcatt ttttatcacc aatccattgc cactgcgatt
    18181 taccagtaac tttttaaagg tcgctttatt taccggagca atacccgctg gccggtaaaa
    18241 caacttaatt ctgttttgca tcgcaaactt cagtgcattc ttaccttctt gttctggact
    18301 atttggtgga atatccagaa cattcagata aaaaatactc tctttattag tgggtagttt
    18361 attcggcata attttaattt ttacttgctg cccggaattt gcccctattt ttgccactgg
    18421 tggcgttaac atgaaaggaa cctgaatttt ttctggtggt aatgacgtat cgccatcatc
    18481 aatccacgcc tgcatcagcg aagaacgatt tccctggttc atcagctgca ccatcacttc
    18541 tttgtgctct gccgggtaaa taatacgcgt cccgtagata acaataccgg catgtgcagg
    18601 aaggaccata gaagaaatga gtaaagctaa taatcctttc atcttaatgc ctcttaaatt
    18661 aaaaggccgc catggggata gcggccatgt taattacctg aagaatcttg caattttatt
    18721 tattaatcct gcgccacacg cataaccagg gaagataaca catcacctga attcactgag
    18781 ttatctgtca gtttcaggta ttttgcttta aacggaatgg catattgacc gtccgctatt
    18841 ttataactct cgatgttgaa aggtgcagaa acatccagga catcgctgtt atcacctaaa
    18901 tagagataat aacccacggt atcgttgcta ctggctatcg ccttatcgtt tccggttatt
    18961 ttatcgttgg taatcaacga gagttttaca ccagcaactt ctttcggaca gctaattttt
    19021 aacatgctgc tggttacacc gactgcatca tcataggtcg agtatttagc tttaccttca
    19081 aagacagtgg ttggtacagt tggcatatta atacttactg aatcgccacc cgcttcgaat
    19141 ttacacggag attctgcaat attcccttta atggttaatg ttccggtatc aacgtctgcg
    19201 gcaaataccc cagcgctcat aaaaaaagaa gaaaaaacag cggcagcaat aattgaacgt
    19261 ttcataatat gctccttaat aaaatctatt tttggttgtt aagagtctgt atctcttgga
    19321 aacaaatttc tcacaccaaa aaagttgccg caatgtaaac acattgtttt attgatttaa
    19381 agcaaattaa ctattgcaat ataaatacaa caaatactta agcacattaa atatttatca
    19441 aatct
//
LOCUS       DAPOXO010000094        19387 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.094, whole genome shotgun sequence.
ACCESSION   DAPOXO010000094 DAPOXO010000000
VERSION     DAPOXO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19387
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.094"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            12..320
                     /locus_tag="ROH59_004078"
     CDS             12..320
                     /locus_tag="ROH59_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806496.1"
                     /translation="MNDVQNRRILALLNMLYYALGNRTTCDICHKYFILVLSVMNNLT
                     INYGSQTSPELTGISYEDANDLITELILFIEDVNADNDMEYPAHLNKIQALLNFAVAN
                     "
     gene            complement(377..967)
                     /gene="cobO"
                     /locus_tag="ROH59_004079"
     CDS             complement(377..967)
                     /gene="cobO"
                     /locus_tag="ROH59_004079"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HDX4806497.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEDVIQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPIKHAFDAGVKAQIGIDY"
     gene            complement(964..1722)
                     /locus_tag="ROH59_004080"
     CDS             complement(964..1722)
                     /locus_tag="ROH59_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HDX4806498.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSEDCQQLAQRIAVNYPRLDGVLHNAGL
                     LGDVCPMSEQDPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
     gene            1942..2991
                     /gene="sohB"
                     /locus_tag="ROH59_004081"
     CDS             1942..2991
                     /gene="sohB"
                     /locus_tag="ROH59_004081"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HDX4806499.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDTHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVVTDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            complement(3027..3278)
                     /locus_tag="ROH59_004082"
     CDS             complement(3027..3278)
                     /locus_tag="ROH59_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HDX4806500.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            3658..6255
                     /gene="topA"
                     /locus_tag="ROH59_004083"
     CDS             3658..6255
                     /gene="topA"
                     /locus_tag="ROH59_004083"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDX4806501.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSTA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
     gene            6465..7439
                     /gene="cysB"
                     /locus_tag="ROH59_004084"
     CDS             6465..7439
                     /gene="cysB"
                     /locus_tag="ROH59_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HDX4806502.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK"
     gene            7734..7898
                     /locus_tag="ROH59_004085"
     CDS             7734..7898
                     /locus_tag="ROH59_004085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HDX4806503.1"
                     /translation="MLISDGDYMRLAMPSGNQEPRRNPELKRKAWLAVFLGSALFWVV
                     VALLIWKLWG"
     gene            7901..8068
                     /locus_tag="ROH59_004086"
     CDS             7901..8068
                     /locus_tag="ROH59_004086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_304581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806504.1"
                     /translation="MVGQEQLESSPLCQHSDNEPEAKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            8182..8277
                     /locus_tag="ROH59_004087"
     CDS             8182..8277
                     /locus_tag="ROH59_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806505.1"
                     /translation="MINTNMKYWSWMGAFSLSMLFWAELLWIITH"
     gene            8427..11102
                     /gene="acnA"
                     /locus_tag="ROH59_004088"
     CDS             8427..11102
                     /gene="acnA"
                     /locus_tag="ROH59_004088"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HDX4806506.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSFKV
                     LLENLLRWQDGKSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSE
                     DQVELVEKYAKAQGMWRNPGDEPIFTSVLELDMNDVEASLAGPKRPQDRVALPDVPKA
                     FAASSELEVNATHKDRLPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNI
                     NLASEPIGHDRKGEPVFLKDIWPSAQEIARAVDQVSTEMFRKEYAEVFEGTAEWKEIN
                     VTRSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTR
                     HLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSNLIGMGILPLEFPQGVTRKTLELTGEEKIDIGDLQNLQPGATVPVTLTRADG
                     SQEVVPCHCRIDTATELTYYQNDGILHYVIRNMLK"
     gene            complement(11166..11756)
                     /gene="ribA"
                     /locus_tag="ROH59_004089"
     CDS             complement(11166..11756)
                     /gene="ribA"
                     /locus_tag="ROH59_004089"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HDX4806507.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIIERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            11926..12690
                     /gene="pgpB"
                     /locus_tag="ROH59_004090"
     CDS             11926..12690
                     /gene="pgpB"
                     /locus_tag="ROH59_004090"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HDX4806508.1"
                     /translation="MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAIMLFAILAAAILMGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            12839..13147
                     /gene="lapA"
                     /locus_tag="ROH59_004091"
     CDS             12839..13147
                     /gene="lapA"
                     /locus_tag="ROH59_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HDX4806509.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVAPHSSAAKE
                     "
     gene            13154..14323
                     /gene="lapB"
                     /locus_tag="ROH59_004092"
     CDS             13154..14323
                     /gene="lapB"
                     /locus_tag="ROH59_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HDX4806510.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
                     IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSI
                     MMGRVFMAKAEYAKAVESLQRVISQDRELVSETLEMLQTCYQLLGKTAEWAEFLQRAV
                     EENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
     gene            14515..15252
                     /gene="pyrF"
                     /locus_tag="ROH59_004093"
     CDS             14515..15252
                     /gene="pyrF"
                     /locus_tag="ROH59_004093"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDX4806511.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDAALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQFVRELQQRDFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMAAAREALVPFGKDAPLLIAVTVLTSMEACDLADLGVTLSPADYAERLAALTQK
                     CGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSDAGDQRRIMTPEQALAAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            15252..15578
                     /gene="yciH"
                     /locus_tag="ROH59_004094"
     CDS             15252..15578
                     /gene="yciH"
                     /locus_tag="ROH59_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HDX4806512.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGIIEIQGDKRDLLKSMLEAKGMK
                     VKLAGG"
     gene            complement(15704..15922)
                     /gene="osmB"
                     /locus_tag="ROH59_004095"
     CDS             complement(15704..15922)
                     /gene="osmB"
                     /locus_tag="ROH59_004095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HDX4806513.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(16191..16940)
                     /locus_tag="ROH59_004096"
     CDS             complement(16191..16940)
                     /locus_tag="ROH59_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4806514.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEQSKLTVHVVDI"
     gene            complement(17029..17202)
                     /locus_tag="ROH59_004097"
     CDS             complement(17029..17202)
                     /locus_tag="ROH59_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806515.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            complement(17350..19335)
                     /gene="pdeR"
                     /locus_tag="ROH59_004098"
     CDS             complement(17350..19335)
                     /gene="pdeR"
                     /locus_tag="ROH59_004098"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDX4806516.1"
                     /translation="MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTEITEPDRIL
                     QLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWGGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPTRKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQELIDHAINQADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGISLSPEHGSDSAAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSRLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
BASE COUNT         4956 a         4552 c         4958 g         4921 t
ORIGIN      
        1 aggaggtcat tatgaacgat gtgcaaaatc gacgaatact ggcattgctc aatatgctgt
       61 actatgcctt aggaaaccga acaacctgcg atatatgtca caaatatttt attctggttt
      121 tgtcagtaat gaataatctg acaattaatt atggctcgca aacgtcacca gaactgacgg
      181 gtattagtta tgaagatgct aatgatttga tcactgaatt aatactgttt attgaagacg
      241 tcaatgcgga taatgatatg gaatatcccg cacacttgaa taaaattcaa gctcttctta
      301 attttgccgt ggctaattaa gccattcagt atctaaaatt agcacctcaa gaggcgaact
      361 tttgaggtgc tttcacttag taatcaatcc ctatctgcgc ttttacaccg gcatcaaacg
      421 catgtttgat ggggcgcagc tcacttaccg tatccgccag ttcaagaata tcccgatgac
      481 agcctcgacc cgtgataatc accgtctgtt gatgtggacg ttcatttaac gcctgaatca
      541 cgtcttccag tggcaaatag tcatacgcta ccatatatgt cagttcatcg agcaaaacca
      601 tatccagtga ggaatcagcc agcatccgct ttgcatgttg ccagacttcg cggcaggcgg
      661 cggtatcgga ctctcggttt tgtgtatccc aggtaaagcc cgttgccatt acctgaaact
      721 caacgccgtg tggctccagc agatttcgtt caccattagg ccaggtgcct ttaataaact
      781 gcacgacgcc cacttttttt ccgtgaccaa ctgcgcgtgt tgccgtacca aatgccgcgg
      841 tggttttgcc ttttccattg ccggtaaaga cgatgataat accgcgttca tcctgggcct
      901 gggccacacg agcatctact ttttctttca ctcgctgctg acgctgttgg tagcgttcat
      961 cactcattgg gaaattcctg gtttacggcc cggttgggcg tcaaaggtca tgccggtttt
     1021 acggcggctg tcatcgccca tcagccagag gtagagcggc atgatatcag cgggggtttt
     1081 aagtttctgt ggatcttcgg tcgggaaggc actggcccgc attgcggtgc gcgtaccgcc
     1141 tgggttaatg cagttgacac gcaggcgctg ctgatattca tcggccagta cctgcatcat
     1201 cccttcggtg gcaaatttcg acgctgcata tgcgccccag tttgcacgcc cctgacgtcc
     1261 aacgcttgat gaggtaaaga ccagtgaacc ggcgtcggat ttgagtaata aaggaagcag
     1321 tgcctgggtg agcataaagg tggcattaac gttgacctgc atgacgtcct gccagacttg
     1381 cggatcttgt tcgctcattg ggcaaacatc gccgagcaat ccggcattat gcaaaacacc
     1441 atccagacgc ggataattaa cggcaatgcg ctgtgccagt tgttggcaat cttcggacgt
     1501 gcaggttagc aaatcgagaa taaaccactg tggctgacgt ccagtttctt cgtttatgtg
     1561 gctggctacc tgacgtaatt tttcttcatt acggcccaaa agaatcactg tcgcaccata
     1621 gcgtgcatac gtcatcgctg cttcacgacc aattccatcg ctggctcccg tcaccagaat
     1681 aatgcgatca ttgagtaaat cttgttttgg ctggtaatgc atggctactc ctcaacgacg
     1741 ttgtctgtcg cgctgccagt gtactttatg actttggggc tttatgcctg aaacagaagg
     1801 gcatttcaat cagcctgggg cgataacacc gcaaaatgga tactttgtca tactttcgct
     1861 gcaataacat ctctgcgaga cggctaaaca tgcctgttgt aaactgtgag ccaaagcgtt
     1921 gtttaaccaa ggtggggact cgtggaattg ttgtctgaat atggtttgtt tttggcgaaa
     1981 atcgttaccg ttgtgctagc gattgcggcg attgccgcca ttattgtcaa tgttgctcaa
     2041 cgtaataaac gccagcgtgg cgagttacga gtcaacaatc tcagcgaaca gtataaggag
     2101 atgaaagaag aactggccgc ggcgctgatg gacactcatc agcaaaaaca gtggcacaaa
     2161 gcgcagaaga aaaagcacaa gcaagaagcg aaagccgcaa aagcgaaagc taaactgggc
     2221 gaggtggtaa ctgacagtaa accccgcgtc tgggtgctgg attttaaagg cagcatggac
     2281 gcccatgaag tgaactctct acgtgaagag ataacggcgg tactcgcagc attcaaaccg
     2341 caggatcagg ttgtgctccg tctggaaagc ccaggtggca tggtgcatgg ttacgggttg
     2401 gcggcttcgc agttgcagcg tctgcgtgat aaaaacattc ctttaactgt tacggtagac
     2461 aaagtcgctg ccagcggcgg ttacatgatg gcctgtgtgg cggacaaaat tgtttccgca
     2521 ccgtttgcta ttgtgggttc cattggggtg gtggcgcaaa tgcccaactt taaccgcttc
     2581 ctgaaaagca aagatattga tatcgaactg cacaccgccg ggcagtataa gcgcacgctg
     2641 acgttgctgg gtgaaaatac cgaagaaggg cgggagaaat tccgcgaaga gttgaacgaa
     2701 acgcatcagt tatttaaaga ttttgtgaag cgtatgcgtc cgtctctgga tattgaacag
     2761 gtggcaacgg gtgaacactg gtacggacaa caggcagtag agaaaggcct ggttgatgaa
     2821 atcaacacca gtgatgaagt tattcttagc ctgatggaag gccgggaagt ggtcaatgta
     2881 cgctatatgc agcgtaaacg actcattgac cgattcaccg gcagcgcggc agagagcgcc
     2941 gatcgattgt tgttacgctg gtggcagcgt gggcaaaagc cgttgatgta aaagacaaac
     3001 gcgaggataa gacctcgcgt tttgctttaa tcaaccaggt gatatttttc tgaaagcaca
     3061 tgggccaggt gtttgaacat attaaacacc gcggtgcttt tggcagttgg taatccttgt
     3121 tcatctaaaa agtagtcgcc ggtaaatacc agcacgccat tacgctgcgt gacgccggtg
     3181 gcttcaatcc ctgcgagcgt atcctcatgc tcacgaatga ttttgttggc ctctttcaac
     3241 agcgtttcgc ggtcgatggg ttgagtctct ttgttcatta tttactcctt aaacaaggac
     3301 attagtctac gccaggcatg gcttgcagac aaatatacca cgctggtggc aagagcgcct
     3361 tactggcaac tttggatttt gcatgctaat aaagttgcgt atcggatttt atcaggtaca
     3421 gtgtgacgct ttcgtcaatc tggcaataga tttgcttgac attcgaccaa aattccgtcg
     3481 tgctatagcg cctgtaggcc aagacctgtt aactcagtca cctgaatttt cgtgagcaga
     3541 gtcacgacaa ggggttgata tccgcagaga gcgagtccat atcggtaact cgttgccagt
     3601 ggaaggttta tcaacgtgcg acgcattcct ggaagaatca aattaggtaa ggtgaatatg
     3661 ggtaaagctc ttgtcatcgt tgagtccccg gcaaaagcca aaacgatcaa caagtatctg
     3721 ggtagtgact acgtggtgaa atccagcgtc ggtcacatcc gcgatttgcc gaccagtggc
     3781 tcaactgcca aaaagagtgc cgactctacc tccaccaaga cggctaaaaa gcctaaaaag
     3841 gatgaacgtg gcgctctcgt caaccgtatg ggggttgacc cgtggcacaa ttgggaggcg
     3901 cactatgaag tgttgcctgg taaagagaag gtcgtctctg aactgaaaca actggctgaa
     3961 aaagccgacc acatctatct cgcaaccgac cttgaccgcg aaggggaagc cattgcatgg
     4021 cacctgcggg aagtgattgg tggtgatgat gcgcgctata gccgagtggt gtttaacgaa
     4081 attactaaaa acgcgatccg ccaggcattt aacaaaccgg gtgagctgaa tattgatcgt
     4141 gttaatgccc agcaggcgcg tcgctttatg gaccgcgtgg tggggtatat ggtttcgccg
     4201 cttctatgga aaaagatcgc tcgtggtctg tctgccggtc gtgtgcagtc ggtggcggtc
     4261 cgcctggtgg tcgagcgtga gcgtgaaatt aaagcgttcg taccggaaga gttctgggaa
     4321 gtcgatgcca gcacgaccac gccatctggt gaagcgttgg cgttgcaggt gactcatcag
     4381 aacgacaaac cgttccgtcc ggtcaacaaa gaacaaactc aggctgcggt aagtctgctg
     4441 gaaaaagcgc gctacagcgt gctggaacgt gaagacaaac cgacaaccag taaacctggc
     4501 gctcctttta ttacctctac gctgcaacaa gctgccagca cccgtcttgg ttttggcgtg
     4561 aaaaaaacca tgatgatggc gcagcgtttg tatgaagcag gctatatcac ttacatgcgt
     4621 accgactcca ccaacctgag tcaggacgcg gtaaatatgg ttcgcggtta tatcagcgat
     4681 aattttggta agaaatatct gccggaaagt ccgaatcagt acgccagcaa agaaaactca
     4741 caggaagcgc acgaagcgat tcgtccttct gacgtcaatg tgatggcgga atcgttgaag
     4801 gatatggaag cagatgcgca gaaactgtac cagttaatct ggcgtcagtt cgtagcctgc
     4861 cagatgaccc cagcgaaata tgactccacg acgctgaccg ttggtgcggg cgatttccgc
     4921 ctgaaagcac gcggtcgtat tttgcgcttt gatggctgga cgaaagtgat gcctgcactg
     4981 cgtaaaggcg atgaagatcg tatcttaccg gcagtcgata aaggcgatgc tctgacgctc
     5041 gttgaactga caccagccca gcactttacc aagcctccag cccgtttcag tgaagcatcg
     5101 ctggtcaaag agctggaaaa acgcggtatc ggtcgtcctt ctacctatgc gtcgatcatt
     5161 tcgaccattc aggatcgtgg ctatgtgcga gtagaaaatc gtcgtttcta tgcggaaaaa
     5221 atgggcgaaa tcgtcaccga tcgcctggaa gagaatttcc gcgagttaat gaactacgac
     5281 ttcaccgcgc agatggaaaa cagcctcgac caggtggcaa atcacgaagc agagtggaaa
     5341 gctgtactgg atcacttctt ctcggatttc acccagcagt tagataaagc tgaaaaagat
     5401 ccggaagagg gtggtatgcg cccgaaccag atggttctga ccagcattga ctgcccgact
     5461 tgtggtcgca aaatggggat tcgcacagcg agcaccgggg tattccttgg ctgttctggc
     5521 tatgcgctgc cgccgaaaga gcgttgcaaa accaccatta acctggtgcc ggaaaacgaa
     5581 gtgctgaacg tgctggaagg tgaagacgct gaaaccaatg cgttgcgcgc aaaacgtcgt
     5641 tgcccgaaat gtggcacggc gatggacagc tatctcatcg atccgaaacg taagttgcat
     5701 gtctgtggta ataacccaac ctgcgacggt tacgagatcg aagagggtga attccgcatt
     5761 aaaggttatg acggcccgat cgttgagtgt gaaaaatgtg gctctgaaat gcacctgaaa
     5821 atggggcgtt tcggtaaata catggcctgc accaacgaag agtgtaaaaa cacacgtaag
     5881 attttacgta acggcgaagt ggcaccaccg aaagaagatc cggtgccatt accggagctg
     5941 ccgtgcgaaa aatcagatgc ctatttcgtg ttgcgtgacg gtgctgccgg tgtgttcctg
     6001 gcggccaata ccttcccgaa atcgcgtgaa acgcgtgcgc ctctggtgga ggagctttat
     6061 cgcttccgcg accgtctgcc ggaaaaactg cgttatctgg ccgatgcgcc acagcaggat
     6121 ccggaaggta ataagaccat ggttcgcttt agccgtaaaa ccaaacagca atatgtctct
     6181 tcggaaaaag acggaaaggc gactggttgg tcagcatttt atgttgatgg caaatgggtt
     6241 gaagggaaaa aataaccttt aattccgtct ggtttttata aacaaagggt cgcgaaagcg
     6301 gccctttttt attgcatatt attttttctt cacacctata cactaaggct ataaatgata
     6361 tagtggttat agttagcacc ttttttatta ttaaatcgta ttagtcaccc gcctggtgtg
     6421 gcgaaaaaac gatgttctga tggcgtctaa gtggatggtt taacatgaaa ttacaacaac
     6481 ttcgctatat tgttgaggtg gtcaatcata acctgaatgt ctcatcaacg gcggaaggac
     6541 tttacacatc acaacccggg atcagtaaac aagtcagaat gctggaagac gagctgggca
     6601 ttcaaatttt ttcccgaagc ggcaagcacc tgacgcaggt aacgccagca ggacaagaaa
     6661 taattcgtat cgctcgtgaa gttctgtcga aagtcgatgc cataaaatcg gtcgccggag
     6721 agcacacctg gccggataaa ggctcgctgt atatcgccac cacgcatact caggcacgct
     6781 atgcgttacc aaacgttatc aaaggcttta ttgagcgtta tcctcgcgtt tctttgcata
     6841 tgcaccaggg ctcgccgaca caaattgctg atgccgtctc taaaggcaat gccgatttcg
     6901 ctatcgccac ggaagcgctg catctgtatg aagatttagt gatgctaccg tgctaccact
     6961 ggaatcgggc tatagtagtc actccggatc acccgctggc aggtaaaaaa gccattacca
     7021 ttgaagaact ggcgcaatat ccgttggtga catatacctt cggctttacc ggacgttcag
     7081 aactggatac tgcctttaac cgcgcagggt taacgccgcg tatcgtcttc acggcaacgg
     7141 atgctgacgt cattaaaact tacgtccggt tagggctggg ggtaggggtc attgccagca
     7201 tggcggtgga tccggtcgcc gatcccgacc ttgtgcgtgt tgatgctcac gacatcttca
     7261 gccacagtac aaccaaaatt ggttttcgcc gtagtacttt tttgcgtagt tatatgtatg
     7321 atttcattca gcgttttgca ccgcatttaa cgcgtgatgt cgttgatgcg gctgtcgcat
     7381 tgcgctctaa tgaagaaatt gaggtcatgt ttaaagatat aaaactgccg gaaaaataat
     7441 ttcttgcgtt attttcggca ccttttatgt agcgaaggtg ccggaatata ttctcctttg
     7501 ttacttattt gtatccggtg cacaatattt ttatccctca tatttatagg gtaaattacc
     7561 tgtaaagtag tgtctaatta cacacctcgc aaactccagt tttcaaatat ctatttcagg
     7621 tcaaaagatt gaattattca ctggagacga ttcgtaaatt cgctggattt ttgactaaag
     7681 tttctttagg atttgtctca tcgtatgatt aattacacca atcgttcaac gtcttgctga
     7741 taagtgatgg cgattatatg aggttagcaa tgccttctgg aaatcaggaa ccccgccgca
     7801 atcctgaatt aaaacgtaaa gcctggctgg cggtttttct tggttctgca cttttctggg
     7861 tggttgtcgc actgcttatt tggaaattgt ggggataacc atggtcggtc aggagcaact
     7921 ggagtcgtca ccattatgtc agcatagtga caatgaacca gaagcaaaac gggaatgttc
     7981 cgtcgttatt ccagacgact ggcaactaac atcgcagcaa caagccttta tagaactgtt
     8041 tgctgaagat gatcagccga aacaataatt atcatcattc ttattaccca tttttaatga
     8101 attacagggc ttttaataca ccgcagcaat aacaggttga gttatctcaa cacaaagtaa
     8161 taaccgttaa gggtgtagcc tatgatcaac acaaatatga aatattggtc ctggatgggc
     8221 gcattttctc tgtcgatgct cttctgggcc gaactcctct ggatcattac tcactgatcc
     8281 ctgatcccgc tgtttgcttt gcctcaaggt ttctcctctt ttatcaattt gggttgttat
     8341 caaatcgtta cgcgatgttt gtgttatctt taatattcac cctgaagaga atcagggctt
     8401 cgcaaccctg tcattaagga ggagctatgt cgtcaaccct acgagaagcc agtaaggaca
     8461 cgttgcaggc caaagataaa acttaccact actacagctt gccgcttgct gccaaatcac
     8521 tgggcgatat cacccgtcta cccaagtcat tcaaagtttt gctcgaaaac ctgctgcgtt
     8581 ggcaggatgg taaatcggtt accgaagagg atatccacgc gctggcggga tggctgaaaa
     8641 atgcccatgc tgaccgtgaa attgcctacc gcccggcaag agtgctgatg caggacttta
     8701 ccggcgtacc tgccgttgtt gatctggcgg caatgcgcga agcggttaaa cgcctcggcg
     8761 gcgatactgc aaaggttaat ccgctctcac cggtcgacct ggtcattgac cactcggtga
     8821 ccgtcgatcg ttttggtgat gatgaggcat ttgaagaaaa cgtacgcctg gaaatggagc
     8881 gcaaccacga acgttatgtg ttcctgaaat ggggaaagca ggcgttcagt cggtttagcg
     8941 tcgtgccgcc aggcacaggc atttgccatc aggttaacct cgaatatctc ggcaaagcag
     9001 tgtggagcga attgcaggac ggtgaatgga ttgcttatcc ggatacactc gttggtactg
     9061 actcgcacac caccatgatc aacggccttg gcgtgctggg gtggggcgtt ggtggcatcg
     9121 aagcagaagc cgcaatgtta ggccagccgg tttccatgct tatcccggac gtagtgggct
     9181 ttaaacttac cggaaaatta cgtgaaggta ttaccgccac agacctggtt ctcactgtta
     9241 cccaaatgtt gcgcaaacat ggcgtggtgg ggaaattcgt cgaattttat ggtgatgggc
     9301 tggattcact accgctggcg gatcgcgcca ccattgccaa tatgtcgcca gaatatggtg
     9361 ccacctgtgg cttcttccca atcgatgctg tcaccctcga ttacatgcgt ttaagcgggc
     9421 gcagtgaaga tcaggtcgag ttggtcgaaa aatatgccaa agcgcagggc atgtggcgta
     9481 atccgggcga tgaaccaatt tttaccagtg tgttagaact ggatatgaat gacgttgaag
     9541 cgagcctggc agggccaaaa cgcccgcagg atcgcgttgc actgcccgat gtaccaaaag
     9601 catttgctgc cagtagcgaa ctggaagtga atgccacgca taaagatcgc ctgccggtcg
     9661 attatgttat gaacggacat cagtatcagt tacctgatgg cgctgtggtc attgctgcga
     9721 taacgtcgtg caccaacacc tctaacccaa gtgtgctgat ggccgcaggc ttgctggcga
     9781 aaaaagccgt aactctgggc ctcaagcggc aaccatgggt caaagcgtcg ctggcaccgg
     9841 gttcgaaagt cgtttctgat tatctggcaa aagcgaaact gacaccgtat ctcgatgaac
     9901 tgggatttaa ccttgtggga tacggttgta ccacctgtat tggtaactcg ggaccgttgc
     9961 ccgatcctat cgaaacggca atcaaaaaag gcgatttaac cgtcggtgca gtgctgtccg
    10021 gcaaccgtaa ctttgaaggc cgtatccatc cgctggttaa aaccaactgg ctggcctcgc
    10081 cgccgctggt ggttgcctat gcgctggcgg gaaatatgaa tatcaatctg gcttctgagc
    10141 ctatcggcca tgatcgcaaa ggcgagccgg tatttctgaa agatatctgg ccatcggcac
    10201 aagaaattgc ccgtgcggta gaccaagtct ccacagaaat gttccgcaaa gagtacgcag
    10261 aagtttttga aggcacagcc gagtggaagg aaattaacgt cacacgatcc gatacctacg
    10321 gttggcagga ggattcaacc tatattcgct tatcgccttt ctttgatgaa atgcaggcaa
    10381 caccagcacc tgtggaagat attcacggtg cgcggatcct cgcaatgctg ggggattcag
    10441 tcaccactga ccatatctct ccggcgggca gtattaagcc cgacagcccg gcgggtcgat
    10501 atctacaagg tcggggtgtt gagcggaaag actttaactc ctatggttcg cggcgtggta
    10561 accatgaagt gatgatgcgc ggcaccttcg ccaatattcg catccgtaat gaaatggtgc
    10621 ctggcgttga aggggggatg acgcgccatt tacctgacag cgatgtcgtc tctatttatg
    10681 atgccgcaat gcgctataag caggagcaaa cgccgctggc ggtgattgcc gggaaagagt
    10741 atggatcagg ctccagccgt gactgggcgg caaaaggtcc gcgtctgctt ggtattcgtg
    10801 ttgtgattgc cgaatcgttt gaacgaattc accgttcgaa tttaataggc atgggcatcc
    10861 tgccgctgga atttccacaa ggtgtgacgc gtaaaacgtt agagcttacc ggggaagaga
    10921 agattgatat tggtgatctg caaaatctac aacccggcgc gacggttccg gtgacgctta
    10981 cgcgcgcgga tggtagccag gaagtcgtac cctgccattg tcgtatcgac accgcgacgg
    11041 agttgaccta ctaccagaac gacggcattt tgcattatgt cattcgtaat atgttgaagt
    11101 aacgagtatt tgcttgccgg ttattttgct tccggcaagc aaattaatta cacaatgcaa
    11161 gagggttatt tgttcagcaa atgacccatt ttctcggctt tggtatcgag ataatgttcg
    11221 ttattggggt tgcgacctac aatcaacggt acgcgttcaa taatattaat ccctgcttcg
    11281 gtcagaattt cgactttttt cgggttattg gttaacaagc ggacttcatt gacgccaagg
    11341 agtttgaaca tatcagcgca aagagtgaag tcgcgctcat cagcggcgaa gcctaactgg
    11401 tggttagcct ctacagtatc gtaaccttga tcctgcagtg cgtaagcgcg gattttattc
    11461 agcagaccaa tgttacgacc ttcctgacgg tgatacagca aaataccacg gccttcctcg
    11521 gcaatttgcg tcaatgccgc ttcgagctgg aagccacaat cgcagcgcaa gctgaacagg
    11581 gcgtcaccgg tcagacattc ggaatggacg cgcgcaagta ccggggtatg cccggaaata
    11641 tcgccataga ctagcgcgac atgatcgtgt ccggttgcca gttcttcaaa tcccaccatc
    11701 aggaaatcgc cccatggggt tggcagtttg gcttctgcca cacgtttaag ctgcatgaaa
    11761 ttctccagat aatgctggtt ctgtattggc ttattttgcc ataacgagaa ggggttcacc
    11821 taatcacgac gcgtcgatcg ttcacggaat ggcacaaatc tgtcaatttt tcctggaact
    11881 ggcattttca gttatgattg tgggacttat caaaaaggag aggccatgcg ttcgattgcc
    11941 agacgtaccg cagtgggagc tgcactattg cttgtcatgc cagtagccgt atggatttct
    12001 ggctggcgtt ggcaacctgg agaacaaagt tggttactaa aagcggcttt ttgggttact
    12061 gaaactgtca cccagccctg gggcgtcatt acacatttga ttttattcgg ctggtttctc
    12121 tggtgtctgc gttttcgcat taaggctgcc attatgttat ttgccattct ggcggcagca
    12181 atccttatgg gacaaggcgt taaatcctgg atcaaagaca aagtccagga accacgacct
    12241 tttgttatct ggctggaaaa aacacatcat attccggttg atgagttcta cactttaaag
    12301 cgagcagaac gcggaaatct ggtgaaagaa cagttggctg aagagaaaaa tatcccacaa
    12361 tatttgcgtt cacactggca gaaagagacg gggtttgcct ttccttccgg tcacacgatg
    12421 tttgctgcca gttgggcact gctggccgtt ggtttgctgt ggccgcgtcg gcgaacgtta
    12481 accattgcta tcttgttggt ctgggcaacg ggagtcatgg gaagccgcct gctgctcggg
    12541 atgcattggc cacgcgatct ggttgtagct acgttgattt cgtgggcgct ggtggcggtg
    12601 gcaacgtggc ttgcgcaacg aatttgtggg ccattaacac cacctgcgga agaaaatcgc
    12661 gaaatagcgc aacgagaaca agaaagttaa cgctggttga ttttccgaat ttagccctta
    12721 aatcatcaac aatgcgcgtg gatgccattt cgcagacggc gcgaaaatgg tactttaaag
    12781 ggctattgcg gtaagttgac cataatttat tcgctctaac cacataacgg gaagtaatgt
    12841 gaaatattta ctcattttct tactggtgtt agcgatcttc gtgatttcgg tcacgttggg
    12901 tgcgcagaac gatcaacagg tgacgtttaa ttatctgtta gcgcaagggg agtaccgtat
    12961 ttccacattg ctggcggtat tgtttgctgc ggggtttgct atcggttggt tgatttgcgg
    13021 cctgttctgg ctgcgagttc gtgtttccct ggcgcgcgct gaacgtaaaa taaagcgact
    13081 ggaaaaccag ctttcacccg cgactgacgt ggctgtagcg ccgcactcgt ctgcggcgaa
    13141 ggaataactt tctatgctgg agttgttgtt tctgcttttg cctgtagccg ctgcctatgg
    13201 ctggtatatg ggccgcagaa gtgcgcaaca aaacaagcaa gatgaagcca accgcttgtc
    13261 gcgtgattac gtagcggggg ttaacttcct gcttagtaat caacaggata aagcggtaga
    13321 cctgtttctc gatatgctta aagaggatac aggtaccgtt gaagcccacc ttacgctcgg
    13381 aaacctgttc cgttcgcgtg gcgaagttga tcgcgctatt cgcatccatc agaccctaat
    13441 ggaaagcgcc tcgctgacct atgaacagcg gcttttggcg attcaacaac tggggcgtga
    13501 ttacatggct gccgggttat acgaccgcgc ggaagacatg ttcaatcagc tgacagatga
    13561 aactgacttc cgcatcggcg cgctgcaaca actgctacaa atttaccagg ctaccagcga
    13621 gtggcagaaa gcaattgatg ttgccgaacg cctggtgaag ctgggtaaag ataaacagcg
    13681 cgtcgaaatt gcccatttct actgtgagtt agctctgcag catatggcca gcgacgatct
    13741 cgatcgtgcc atgactttgc taaaaaaagg tgcggcggca gataaaaaca gcgcccgcgt
    13801 atccatcatg atgggacgcg tgtttatggc gaaagcagaa tacgccaaag ccgtcgaaag
    13861 tttgcaacgt gtcatatccc aggacagaga actggtcagc gaaacgctgg aaatgctgca
    13921 aacatgctat cagctgttgg gtaaaactgc cgaatgggca gaattcctgc agcgcgcggt
    13981 ggaagagaac accggtgccg atgctgaatt gatgcttgcg gatatcatcg aagcgcgcga
    14041 cggtagtgag gctgcacagg tctatattac gcgccagctt cagcgtcatc cgaccatgcg
    14101 tgtgttccat aaattaatgg attaccactt aaatgaagca gaagaagggc gtgccaaaga
    14161 gagtctgatg gtgctgcgtg acatggttgg cgagaaggta cgtagtaagc ctcgttatcg
    14221 ctgccagaaa tgtggtttta ccgcatacac cctctactgg cattgtccgt cttgtcgggc
    14281 ctggtcaacc attaaaccaa ttcgcggtct tgatggcctg taatttttaa aaaaatccga
    14341 ctttagttac aacatactaa ttattgatct tctattgtgt tccggtaccg acggcgcgga
    14401 aaagcctgcc agaggagaaa tcgcaactgt taatttttta tttccacggg tagaatgctc
    14461 gccgtttacc tgtttcgcgc cacttccggt gcccatcatc aagaaggtct ggtcatgacg
    14521 ttaactgctt catcttcttc ccgcgctgtt acgaattctc ctgtagttgt tgcccttgat
    14581 tatcataatc gcgatgccgc gctggccttt gtcgacaaga tcgacccacg cgattgtcgt
    14641 ctgaaggtcg gcaaagagat gtttacattg tttgggccac agtttgtgcg cgaacttcaa
    14701 cagcgtgatt ttgatatctt tcttgacctg aaattccacg atattcccaa cactgcagcg
    14761 cacgctgtcg ctgctgcggc tgacttaggc gtgtggatgg tgaatgttca tgcctccggt
    14821 ggggcgcgta tgatggccgc agcgcgtgag gcactggttc cgtttggcaa agatgcaccg
    14881 cttttgattg ctgtgacagt gttgaccagc atggaagcct gcgacctggc cgatcttggc
    14941 gtgacactgt cacctgcaga ttatgcagaa cgtctggcgg cactgacgca aaaatgtggc
    15001 cttgatggtg tggtgtgttc tgctcaggaa gctgtgcgct ttaaacaggt attcggtcag
    15061 gagttcaaac tggttacgcc gggcattcgt ccgcagggga gtgatgctgg cgaccagcgc
    15121 cgcattatga cgccagaaca ggcgttggcg gctggtgttg attatatggt gattggtcgc
    15181 ccggtaacgc aatcggtaga tccagcgcag acgctgaaag cgatcaacgc ctctttacag
    15241 cggagtgcat gatgagtgat tccaacagcc gtctggtcta ctcaacggaa accggacgta
    15301 ttgatgagcc aaaagcggcc cctgtacgcc ctaaaggcga cggtgtggtg cgtattcagc
    15361 gtcagaccag tggacgcaaa ggtaagggcg tttgcctgat taccggtgtc gatctcgatg
    15421 atgccgaact gacgaaactg gcagctgaac tgaagaaaaa atgcggctgc ggcggagcag
    15481 taaaagatgg aattattgaa atccagggcg ataagcgtga tttattaaaa tcaatgcttg
    15541 aagcgaaagg gatgaaggta aaacttgcag gcggctaaca taaaaagcca cggatatatc
    15601 cgtggctttc gaatatttta ctgtgtgtat tattcagtta tttcgtactg aacagaatca
    15661 agcgtattat aattgcgagt cgataatcga catttattta cgattattta ccgacctggt
    15721 gaccaataac accaccgacg gctgcaccac ctaatgtacc caacgtactg ccatcggtca
    15781 gtactgcacc gcctaatgcc cctgcacctg cgccgattgc ggtgttgcgg tcccgtttag
    15841 accagttaga acaggcactc agagacattg ccagggtaat tgccagaaca gccgcggtca
    15901 tttttttgct cgttacaaac ataatactct ctcctgaatt tatgattcac ggaagtaagc
    15961 tctctataac tataatagct aagaataagc caggtgaaat tattccgtga aatccgctcg
    16021 cgcgcagggt tatatcacgc aggtgataat gacttcctgt tatatcgctg ataataattt
    16081 tatatcttga gagtgttaat aacaggtaaa tagtcttaat tatcaaccag gaatcatctt
    16141 agagcggatg atttgccaaa ctgcaaatca tccgtagaga agggaaatgg ttaaatgtca
    16201 acgacgtgaa cggtgagttt actttgttca agatgcatca gatcgctggc gcgtattttc
    16261 gaatcggtaa tcacgcgatt gaatcgctca acggggccga tggagtatga atgtacagca
    16321 ccaaatttcg agctgtcggt caggactatc gcctcgcact ctttttccag cacggcattg
    16381 accacatcgg tacgcatcat atcgcgaccg gtaaacccag tttcaggttg ccagccatca
    16441 ataccaataa atgctttgct gaaatgcacc tgttggatgc actggcgtgt caaagggcca
    16501 accatacttt cgcttttttt ctggtacacg ccaccgagca aaatgacttc acaaggcgcg
    16561 tctttcagca aatgcgcgat gtagctgctg accgtgatga tagtgacatt tttcttctgc
    16621 tcgcccagag tccgggcgag cagggcattg ctgctaccat tttcgataaa gatggtttcg
    16681 cccggttgaa ccagtgacgc ggcaaactcg gcgagttcac gcttcagcgt atagttgctc
    16741 atcatacggg tttcgacgtc atcactatca agcgaaactg caaaaccatg tgcacgtcgg
    16801 aggtaactca gtttttcgag ggtgttgaga tcctggcgaa tggtaacttc agaaactcca
    16861 gtggcttttg ccagatcggt tacgctaacc tgaccctggt caatgaccat ctgtagaata
    16921 gtttgttgtc gggaattcat cgctgtaatt cttataacgt tataatacta aataaaaaaa
    16981 tactgacgcg ccggcatcct caaataggaa aacctgaagg cacgattgtt aaatctccca
    17041 cggtgccttc gggatgtctg gcgtagattc agcaacctgg cgcaagagtt ctgctttaag
    17101 tatctcgaga ttatggatcg cagagtggta atcgcctgcc acaaggatat ctaacacaat
    17161 atcaatacgt tcggcaacgc gctgggcatc aaattcagac atcaaggaca tccttatagc
    17221 aaaaggggga aaatgaataa tgcaaaaatt gccgctaaaa gagaagggtt taacagcaac
    17281 ggctaattat catccgggaa tacgatatat aatgacggaa tatagcgcta agtatatata
    17341 ttcatctact tatgcgcgct tcagatagcg tttataccag cgttcgaagg cgacggcggg
    17401 catcggtttg gcaaacaaaa atccttgtcg ctcattgatc ccgttcttgg ttaaaaaagc
    17461 atcttccttt gcactttcta caccttcggc gatcacctga agattcaatg cctgggccac
    17521 agcgacgatc gcccggacca gtgattgcga gacaggctgt ttgtgaatat cccgaacaaa
    17581 aacctggtca agtttgatgg catcgatcgg aaagcgcgcc agttgcgaaa gtgaagagta
    17641 gccggtacca aaatcgtcca gatgaacttg cgcacctaat cggctaaatt gttgaataac
    17701 agacagtgcc agttcatcat tctcaatcag gcagctctcc gtcagttcaa catctatagg
    17761 gcagtattca aaattgagtt cctggagaac ctgtttcagg gcggtgaaaa tggtttgatc
    17821 ggcgagctga cgtgcagaaa tatttaccgc tactcgcagg ttaatgcctt tatcccgcca
    17881 cttcgctacc tggcgtacga catcgagaat cacccaacgg cctaaaggca caattagccc
    17941 tgattcttcg gcgtaggaaa tgaagtccaa cggtggaatc aacccacgtt caggtgactg
    18001 ccaacgtact agtgcttcca gactgcgcac ttcaccacgc caggtgattt tcggttgata
    18061 gtgaataacc aactgatcgt tttccagtgc tttacgcaag ttggtatcca gccagagata
    18121 ttcaaatacc ctctgattca tttctggggt aaaaacgcaa aattgtcctc gtccgccttc
    18181 cttcgctgtg tacattgctg tgtcggcgtg acgaataata gccgcgctgt ccgaaccatg
    18241 ttcgggagag agtgaaatac ctactgaaca gctggtataa acttcaatta aaccaatgcg
    18301 aaaggggagc cgtaagcggg tcaaaattcg tgatgccatt gcttccagcg cgctttgtga
    18361 ggtattggat gccagtacca gaaactcatc gccacctgga cgcgccaata cctggtcatg
    18421 ttcgagacag cttaaaatag ccaatgacac gtcgcgtaat aactggtcac caaacaaatg
    18481 cccataggcg tcgttgacct ttttaaaatt atccaaatca agatacacaa ccccaacttt
    18541 attgttatct gcctgattaa tagcgtgatc gattaactcc tgcattgcgt tacgattcgg
    18601 cagtccggtg atactgtcgg tatttgccag aatacgcagt cgctcctgag cgcggcgctc
    18661 ttcggtaatg tcggtgccgg aacagattaa aaaaatctcg tttttgccac tgccgctgtg
    18721 gacaaattta ttgcgaaaca gaaacagccg ctggccttta cgtgttggta tccacagttc
    18781 gacttcatat gcattgccgc ttcgaaaaaa tacacggtta ttgcgcctgg atgccgcagc
    18841 ttcacgacga ctcataaaca gtttaaacac gctttgccca atgacgtcgt gttctttcaa
    18901 gcctgtgtaa tcttcacata accgattaaa gcgctggata ttcccccggc tgtcgagaat
    18961 cactattgcg gaatgtgctt cagaaactac ctgctcagca aaggaaagcc catgtgataa
    19021 atcacgagca accgccggtg tgtcatgcca tgcagacgcg ttgcctcccc attctcgttt
    19081 attgattttt cgtcctacca gatgcacaga aagatcgctt tcatcgacgg tcagactcat
    19141 catcaggctg gaggtgatga ccgtcatttc cctgatgcga gcagcctgtt cggcagatag
    19201 ttgcaaaata cgatcgggtt ctgtgatttc ggtggtagaa aagcgcaaaa catcgctgct
    19261 ttccgtcaac cgccagtatg gattgtgcga tccgagaaag ttgtacaacg ttgtggactc
    19321 cctaacggtt ttcatgatgc atatcctccg gttaacagcg gagtccgcag ttaaataaaa
    19381 ggaacaa
//
LOCUS       DAPOXO010000095        18430 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.095, whole genome shotgun sequence.
ACCESSION   DAPOXO010000095 DAPOXO010000000
VERSION     DAPOXO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18430
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.095"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            78..152
                     /gene="tnaC"
                     /locus_tag="ROH59_004099"
     CDS             78..152
                     /gene="tnaC"
                     /locus_tag="ROH59_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HDX4806517.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            373..1788
                     /gene="tnaA"
                     /locus_tag="ROH59_004100"
     CDS             373..1788
                     /gene="tnaA"
                     /locus_tag="ROH59_004100"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HDX4806518.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDNSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            1880..3127
                     /gene="tnaB"
                     /locus_tag="ROH59_004101"
     CDS             1880..3127
                     /gene="tnaB"
                     /locus_tag="ROH59_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HDX4806519.1"
                     /translation="MTDQSEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWISSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDSTSTTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHAGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            3259..4434
                     /gene="mdtL"
                     /locus_tag="ROH59_004102"
     CDS             3259..4434
                     /gene="mdtL"
                     /locus_tag="ROH59_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HDX4806520.1"
                     /translation="MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSALFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WTMATMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHNA"
     gene            4409..5368
                     /gene="yidZ"
                     /locus_tag="ROH59_004103"
     CDS             4409..5368
                     /gene="yidZ"
                     /locus_tag="ROH59_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HDX4806521.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSSVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNQLLDKPLHETPRGLKFELA
                     AESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLSIDYEVLFSDVPCVWLRKDHPALHEAWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSRNPKIVWLRETIKNLYASMA"
     gene            5525..6274
                     /locus_tag="ROH59_004104"
     CDS             5525..6274
                     /locus_tag="ROH59_004104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HDX4806522.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWELDGKHGWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKAFSPN"
     gene            6296..6862
                     /gene="yieF"
                     /locus_tag="ROH59_004105"
                     /gene_synonym="chrR"
     CDS             6296..6862
                     /gene="yieF"
                     /locus_tag="ROH59_004105"
                     /gene_synonym="chrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I chromate reductase YieF"
                     /protein_id="HDX4806523.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEDGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(6915..8252)
                     /gene="adeP"
                     /locus_tag="ROH59_004106"
     CDS             complement(6915..8252)
                     /gene="adeP"
                     /locus_tag="ROH59_004106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HDX4806524.1"
                     /translation="MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMSVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            8419..9084
                     /gene="yieH"
                     /locus_tag="ROH59_004107"
     CDS             8419..9084
                     /gene="yieH"
                     /locus_tag="ROH59_004107"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HDX4806525.1"
                     /translation="MSQIEAVFFDCDGTLVDSEVICSRAYVTMFREFGIHVDLEEIFT
                     RFKGVKLYEIINIISKEQGVTMIQADAEHVYRAEVARLFDSELEVIAGANELLASVKV
                     PMCVVSNGPVSKMQHSLGKLNMLHYFPEKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSSAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTHLSQLPELWKARGWD
                     ITA"
     gene            9151..9618
                     /locus_tag="ROH59_004108"
     CDS             9151..9618
                     /locus_tag="ROH59_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806526.1"
                     /translation="MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLWVIIH
                     PIFLLLSITTGAIPALLTGVMVACLPEKIGSQKRYRCLAGGIGGVVITEIYCAVIIHI
                     KVMASSVLFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS"
     gene            9667..10254
                     /locus_tag="ROH59_004109"
     CDS             9667..10254
                     /locus_tag="ROH59_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbrC family protein"
                     /protein_id="HDX4806527.1"
                     /translation="MTQNIRPLPLFKYHPKPLETGAFEQDKTVECDCCEQQTSVYYSG
                     PFYCVDEVEHLCPWCIANGSAAEKFAGSFQDDASIEGVEFEYDEEDDFAGIKNTYPDE
                     MLKELVERTPGYHGWQQEFWLAHCGDFCAFIGYVGWNDIKDRLDEFANLEEDCENFGI
                     RNSDLAKCLQKGGDCQGYLFRCLHCGKLRLWGDFS"
     gene            complement(10315..11037)
                     /locus_tag="ROH59_004110"
     CDS             complement(10315..11037)
                     /locus_tag="ROH59_004110"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDX4806528.1"
                     /translation="MKLIITEDYQEMSRVAAHHLLGYMSKMRRVNLAITAGSTPKGMY
                     EYLITLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLT
                     IDNYREHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
                     HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASV
                     LQLHPSLMVIADKAAAAELALG"
     gene            complement(11052..12221)
                     /locus_tag="ROH59_004111"
     CDS             complement(11052..12221)
                     /locus_tag="ROH59_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDX4806529.1"
                     /translation="MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVN
                     TDNSVTFRYFAPGAKNVSVVVGVPVPDNIHPMTKDEAGVWSWRTPVLKGNLYEYFFNV
                     DGVRSIDTGTAMTKPQRQVNSSMILVPGSYLDTRSVVHGDLIAITYHSNALQSERQMY
                     VWTPPGYTGIGEPLPVLYFYHGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPD
                     TETDAKGIIPEDFVPQERRKVFYPLNAKAADRELMNDIIPLISKRFNVRKDADGRALA
                     GLSQGGYQALVSGINHLESFGWLATFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTV
                     VVGDKDVVTGKDIAGLKTELEQKKIKFDYQEYPGLNHEMDVWRPAYAAFVQKLFK"
     gene            complement(12248..13864)
                     /gene="bglH"
                     /locus_tag="ROH59_004112"
     CDS             complement(12248..13864)
                     /gene="bglH"
                     /locus_tag="ROH59_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-specific porin BglH"
                     /protein_id="HDX4806530.1"
                     /translation="MFRRNIITSAILLMAPLAFSAQSLAESLTVEQRLELLEKALRET
                     QSELKKYKDEEKKKYTPATVNRSVSANDQGYAANPFPTSRAAKPDAVLVKNEEKNASE
                     TGSIYSSMTLKDFSKFVKDEIGFSYNGYYRSGWGTASHGSPKSWAIGSLGRFGNEYSG
                     WFDLQLKQRVYNENGKRVDAIVMMDGNVGQQYSTGWFGDNAGGENFMQFSDMYVTTKG
                     FLPFAPEADFWVGKHGAPKIEIQMLDWKTQRTDAAAGVGLENWKVGPGKIDIALVRED
                     VDDYDRSLQNKQQINTNTIDLRYKDIPLWDKATLMVSGRYVSANESASEKDNQDNNGY
                     YDWKDTWMFGTSLTQKFDKGGFNEFSFLVANNSIASNFGRYAGASPFTTFNGRYYGDH
                     TGGTAVRLTSQGEAYIGDHFIVANAIVYSFGNDIYSYETGAHSDFESIRAVVRPAYIW
                     DQYNQTGVELGYFTQQNKDANSNKYNESGYKTTLFHTFKVNTSMLTSRPEIRFYATYI
                     KALENELDGFTFEDNKDDQFAVGAQAEIWW"
     gene            complement(13950..15344)
                     /gene="bglB"
                     /locus_tag="ROH59_004113"
     CDS             complement(13950..15344)
                     /gene="bglB"
                     /locus_tag="ROH59_004113"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglB"
                     /protein_id="HDX4806531.1"
                     /translation="MKAFPETFLWGGATAANQVEGAWQEDGKGITTSDLQPHGVMGKM
                     EPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEAEPNEAG
                     LAFYERLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
                     QHKVVLWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIP
                     EAKIGNMLLGGLVYPLTCQPQDMLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNI
                     TIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWG
                     WQIDPVGLRILLNTLWDRYQKPLFIVENGLGAKDSVEVDGSIQDDYRIAYLNDHLVQV
                     NEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGW
                     YAEVIKTRGLSLKK"
     gene            complement(15363..17237)
                     /gene="bglF"
                     /locus_tag="ROH59_004114"
     CDS             complement(15363..17237)
                     /gene="bglF"
                     /locus_tag="ROH59_004114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIABC"
                     /protein_id="HDX4806532.1"
                     /translation="MTELARTIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLK
                     KTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLGEKAQQAPENDDKGNLLNRFVY
                     VISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILG
                     YTAGKRFSGNPFTAMVIGGALVHPLILTAFENGQKVDALGLDFLGIPVTLLNYSSSVI
                     PIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPITFLLVGPLSTWISELIAA
                     GYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLIPLIINNFTVLGYDTMIPLLMPAIM
                     AQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGAL
                     GATIIGYAQTKVYSFGLPGIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLH
                     FITAKRQPAQVAQQEKTPEIITPEQGGICSPMTGDIVPLIHVADTTFASGLLGKGIAI
                     LPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNVG
                     DKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTVQINAGEPLLSIIR
                     "
     gene            complement(17370..18206)
                     /gene="bglG"
                     /locus_tag="ROH59_004115"
                     /pseudo
     CDS             complement(17370..18206)
                     /gene="bglG"
                     /locus_tag="ROH59_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418179.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator BglG"
BASE COUNT         4691 a         4559 c         4309 g         4871 t
ORIGIN      
        1 catttaaaca atttcagaat agacaaattt cttgagtatt atactgtagc ctcgtgtctt
       61 tcgaggataa gtgcattatg aatatcttac atatatgtgt gacctcaaaa tggtttaata
      121 ttgacaacaa gattgtcgat caccgccctt gatttgccct tctgtagcca tcaccagagc
      181 caaaccgatt agattcaatg tgatcgatta gtttgctata tcttaatttt gccttttaca
      241 aaggccattt ctcgtttatt tacttgtttt agtaaatgat ggtgcttgca tatatatctg
      301 gcgaattaat ggatattgca aatgtaatat tcacagggat cactgtaatt aaaataaatg
      361 aaggattatg taatggaaaa ctttaaacat ctccctgaac cgttccgcat tcgtgttatt
      421 gagccagtaa aacgtaccac tcgcgcttat cgtgaagagg caattattaa atccggtatg
      481 aacccgttcc tgctggatag cgaagatgtg tttatcgatt tactgaccga cagcggcacc
      541 ggggcggtga cgcagagtat gcaggccgcg atgatgcgtg gcgacgaagc ctacagcggc
      601 agccgcagct actacgcgtt agccgagtca gtgaaaaata tctttggtta tcaatacact
      661 attccgactc accagggccg tggtgcagag caaatctata ttccggtact gattaaaaaa
      721 cgcgagcagg aaaaaggcct ggatcgcagc aaaatggtgg cgttctctaa ctatttcttt
      781 gataccacgc agggccatag ccagattaac ggctgtaccg tgcgtaacgt ctatatcaaa
      841 gaagccttcg atactggcgt gcgttacgac tttaaaggca actttgacct tgagggatta
      901 gaacgcggta ttgaagaagt tggcccgaat aacgtgccgt atattgttgc aaccatcacc
      961 agtaactccg caggtggtca gccggtttca ctggcaaact taaaagcgat gtacagcatc
     1021 gcgaagaaat acgatattcc ggtggtcatg gactccgcac gctttgccga aaacgcctat
     1081 ttcatcaagc agcgtgaagc agaatacaaa gactggacca tcgagcagat cacccgcgaa
     1141 acctacaaat atgccgatat gctggcgatg tccgccaaga aagatgcgat ggtgccgatg
     1201 ggcggcctgc tgtgcatgaa agacaacagc ttctttgatg tgtataccga atgcagaacc
     1261 ctttgcgtgg tgcaggaagg cttcccgaca tatggcggcc tggaaggcgg cgctatggag
     1321 cgtctggcgg taggtctgta tgacggcatg aatctggact ggctggctta tcgtatcgcg
     1381 caggtgcagt atctggtcga tggtctggaa gagattggcg ttgtctgtca gcaggcgggc
     1441 ggtcacgcgg cattcgttga tgcaggtaaa ctgttgccgc atatcccggc agatcagttc
     1501 ccggcacagg cgctggcctg cgagctgtat aaagtcgccg gtatccgtgc ggtagaaatt
     1561 ggctctttcc tgttaggccg cgatccgaaa accggtaaac aactgccatg cccggctgaa
     1621 ctgctgcgtt taaccattcc gcgcgcaaca tatactcaaa cacatatgga cttcattatt
     1681 gaagccttta aacatgtgaa agagaacgcg gcgaatatta aagggttaac ctttacctac
     1741 gaaccgaaag tattgcgtca cttcaccgca aaactgaaag aagtttaatt aaaacactca
     1801 gagtggctat aaggatgtta gccactctat taccctacat cctcaataac aaaaatagcc
     1861 ttcctctaaa ggtggcatca tgactgatca atcagaaaaa aaacactctg cattttgggg
     1921 tgttatggtt atagccggta cagtaattgg cggtgggatg tttgctttac ctgttgacct
     1981 tgccggagcc tggttttttt ggggcgcttt tattcttatt atcgcctggt tttcaatgtt
     2041 acattcaggg ctattattat tagaagcaaa cttaaattat cccgtcggtt ccagttttaa
     2101 caccatcacc aaagatttaa tcggtaacac ctggaacata atcagcggta ttaccgttgc
     2161 cttcgttctc tatatcctca cttatgccta tatctctgct aatggtgcga tcattagtga
     2221 aacgatatca atgaatttgg gctatcacgc taatccacgt attgtcggga tctgcactgc
     2281 cattttcgtt gccagcgtat tgtggataag ttcattagcc gccagtcgta ttacctcatt
     2341 gttccttggg ctgaagatta tctcctttgt aattgttttt ggttctttct tcttccaggt
     2401 cgattactcc attctgcgcg attccaccag caccactgcg gggacgtctt acttcccgta
     2461 tatctttatg gctttgccgg tgtgtctggc gtcatttggt ttccacggca atattcccag
     2521 cctgattatt tgctatggca aacgcaaaga taagctcatc aaaagcgtgg tcttcggttc
     2581 gctgctggcg ctggtgattt atctcttctg gctctattgc acgatgggga atatcccgcg
     2641 agaaagcttt aaggcgataa tctcctcagg cggcaacgtt gattcgctgg tgaaatcgtt
     2701 cctcggcacc aaacagcacg gcattatcga attttgcctg ctggtgttct ctaacttagc
     2761 tgttgccagc tcgttttttg gtgtcacgct gggattgttc gattatctgg cggatctgtt
     2821 taagattgat aactcccacg ccgggcgttt caaaaccgtg ctgttaacct tcctgccacc
     2881 cgcgttgttg tatctgatct tcccgaacgg ctttatttac gggatcggcg gtgccggact
     2941 gtgcgccacc atctgggcgg taataattcc tgctgtactg gcaatcaaag cccgcaagaa
     3001 gtttcccaat cagatgttca cggtctgggg cggcaatctt attccggcga ttgtcattct
     3061 ctttggcata accgtaattt tatgctggtt cggtaacgtc tttaacgtgt tacctaaatt
     3121 tggctaaatc tttcaggaag ccagccattc gctggcttct tgcctgtcag gaaatctctt
     3181 ttgtccaaat ggcaactcgc ctgattatcc ttcaccacgt atgctttgcg tcaccttact
     3241 atcaggacgc tttagcccat gtcccgcttt ttgatttgta gttttgccct ggttttactt
     3301 tatcccgcag ggattgatat gtacctcgtt ggtttaccgc gcatcgccgc cgatctcaat
     3361 gccagcgaag cgcagttgca tattgcgttc tccgtttatc tggcggggat ggcggctgcg
     3421 atgttatttg ccggtaaagt ggccgatcgt tcagggagaa agcctgtcgc catacccggc
     3481 gcggcgctat ttattatcgc ctcggtgttc tgttcactgg ctgaaaccag cgcgttattt
     3541 cttgcagggc gatttctaca gggactgggc gcgggctgtt gttacgtagt ggcgttcgcc
     3601 attttgcgcg acacgctgga tgatcgacgt cgggctaaag tgctgtcgtt actcaacggc
     3661 attacctgca tcattccggt gttagcgccg gtgctcggac acctgattat gcttaaattc
     3721 ccttggcaga gtctgttctg gacgatggca acgatgggca tcgcggtact gatgttgtct
     3781 ttgtttattt taaaagaaac gcgccctgcg gcccccgcag cttcggacaa accacgagaa
     3841 aatagcgagt cactgcttaa ccggtttttc ctcagccgtg ttgttatcac caccctcagc
     3901 gtttcggtga tcctcacctt cgtcaacacg tcgccagtat tgctgatgga aatcatgggt
     3961 tttgagcgcg gagaatacgc caccattatg gcgttgaccg ctggcgtcag catgaccgtt
     4021 tcattctcca cgccgtttgc gctgggaatt tttaagccac gtacgttgat gatcacctca
     4081 caggtgttat tcctggcggc ggggatcacc cttgccgttt caccttccca tgcggtttcg
     4141 ctgtttggta tcacgctgat ttgcgccggt ttctcggtag gttttggcgt agcgatgagt
     4201 caggcgttgg ggccgttttc attacgcgcg ggcgtagcca gctcgacctt aggtattgcg
     4261 caagtttgcg gttcgtcact gtggatttgg ctggcggcgg tggttggtat cggtgcatgg
     4321 aatatgctga tcgggattct gattgcctgt agcatagtga gcctgttgct gattatgttc
     4381 gtcgcgcctg gacgcccggt tgccgctcat gaagaaatcc atcacaacgc ttgatctcaa
     4441 tctgctgctc tgtctgcaac tgctgatgca ggagcgcagc gtgaccaaag cggcgaagcg
     4501 gatgaacgtg accccttcgt cggtgagtaa gtcgctggca aagttaagag cgtggtttga
     4561 cgacccgctc tttgtgaact caccgctggg gctgtcgccc acaccgctaa tggtcagcat
     4621 ggagcaaaat ctggcggagt ggatgcaaat gagcaatcag ttgctggaca aaccactcca
     4681 cgaaacgccg cgcggtctta agttcgaact ggcggcggaa tcgccgctga tgatgatcat
     4741 gcttaatgcg ctgtcgaaac ggatctacca acgatacccg caggcgacca tcaaattacg
     4801 taactgggat tacgattcct tagatgccat tactcgtggt gaagtggata ttggtttttc
     4861 cggtcgcgaa agtcatcccc gttcgcggga gctgttaagc tcgctaccgt tatccattga
     4921 ttatgaagtg ctgtttagtg atgtgccctg cgtctggtta cgcaaagatc atccggcact
     4981 gcatgaagca tggaatctgg acaccttttt acgttatccg catatcagca tttgctggga
     5041 acagagcgat acctgggcgc tggacaatgt gttacaggag ctggggcgcg aacgcacgat
     5101 tgctatgagc ctgccggaat tcgagcagtc actgtttatg gcagcacagc ccgacaatct
     5161 gctactggcg accgcgccgc gctactgcca gtactacaat caactccacc aactgccgtt
     5221 ggttgctctt cctctcccgt ttgatgaaag ccagcaaaaa aagctggaag tcccttttac
     5281 ccttctgtgg cataaacgga acagccgtaa tccgaagatc gtctggttac gggaaaccat
     5341 taaaaatctt tacgcgtcga tggcataacc gaatcgtatg aaacgcgacc caatttcaca
     5401 atgaaatgta aaaaagttgt aataaattta tctgaatcga acttttagcc gctttagtct
     5461 gtccatcatt ccagtaaatg attactcttg tattcataat ggaccattaa gcatggagcg
     5521 aaaaatggcg actcactttg cccgagggat tttaacggaa ggacatctga tttctgttcg
     5581 tctcccctcc cagtgtcatc aagaagcccg aaacattccc cctcatcgtc aaagccgttt
     5641 tctggcgtcc agaggtttac tcgcagaact gatgttcatg ctgtatggca ttggcgaatt
     5701 gccggaaatc gtcaccctgc cgaaaggaaa accggttttc agcgataaaa atttgccttc
     5761 gttttctatt tcctatgccg ggaatatggt cggcgtggcg ttaacaaccg aaggtgaatg
     5821 tggcctcgat atggaactac agcgtgcgac acgcgggttt catagcccac acgcgcccga
     5881 taaccacacc ttttccagca atgaatcgct atggatcagt aaacaaaacg atcctaacga
     5941 agcgcgggcg cagctcatca cgctgcgccg gagcgtgcta aaactaaccg gtgatgtttt
     6001 gaatgacgat ccgcgcgatc tgcaactact gcccattgcc ggacgcctga aatgtgctca
     6061 tgtaaatcat gtagaagcgt tatgcgacgc ggaggacgtg ctggtgtggt ccgtggcggt
     6121 cacgcccacg attgaaaagc tcagtgtctg ggagttagat ggcaaacacg gctggaaaag
     6181 cctgcccgat attcacagcc gcgccaacaa tcctaccagc cggatgatgc gttttgccca
     6241 gctctctacc gtgaaggctt tttcgccaaa ttgatagaca accacaggag tcatcatgtc
     6301 tgaaaaattg caggtggtta cgttactggg gagcctgcgc aaaggctcat ttaatggcat
     6361 ggttgcacgt accctgccga aaattgctcc ggcgagtatg gaagtcaatg cgttgccttc
     6421 cattgccgac attcccctgt atgacgctga cgtacagcag gaagacggtt ttccagcaac
     6481 ggttgaagct ctggcggaac agatccgtca ggctgacggt gtggtgatcg tcacgccgga
     6541 atataactac tcggtaccgg gtgggctgaa aaatgccatc gactggcttt cccgcctgcc
     6601 ggatcaaccg ctggctggta aaccggtatt gattcagacc agctcaatgg gcgtgattgg
     6661 cggcgcgcgc tgtcagtatc acctgcgcca gattctggtt ttcctcgatg caatggtgat
     6721 gaacaagcca gaatttatgg gcggcgtgat tcagaacaaa gttgatccgc aaaccgggga
     6781 agtgattgat cagggtacgc tggaccacct gaccgggcaa ttgaccgcat ttggtgagtt
     6841 tattcagcga gttaagatct aaataaaaac ccgccagcaa tcatgcatgg cgggttttta
     6901 acgcgctatc gattttagtg agcgtcgata aagacaatct tcaggataaa cagcagcgca
     6961 acgatgatta cgcacgggct aaggtcacgc agacgtccgg taccaatctt catcacgcag
     7021 taggagataa agcccagcgc gataccttca gtaatcgaga agctgaacgg catcatcaca
     7081 gcggtaataa acgccggaac agattcagta agatcctgcc agttcacgcg agcaagactt
     7141 gaggtcatca acacgccaac gtaaatcagc gcaccagctg cagcgtagcc tggcaccatc
     7201 cccgccagcg gcgacaggaa gataaccagc aggaacagca gaccaacaac cactgccgtc
     7261 agaccggtac gaccgccaac ggaaacgccg gaagaagatt caatatacgc cgtaacagaa
     7321 gaagtaccga taaacgaacc ggtcaccgaa gagatactgt cgacatacag cgcctgcttc
     7381 atgcgcggga atttaccttt ctcatcagcc agacctgctt tatcggtcac gccaatcagc
     7441 gtaccggagg agtcaaacaa gttgaccagc atgaaagaga aaatcacccc tgccagccca
     7501 aggttaaacg acccggctaa atctacatga cccacgacac tcattacgct cggcggcgca
     7561 gaaacgatgc cattatagtg gacatcaccc agcatccagc ccagcagcgt tgtcaccacg
     7621 atggaaacca gcaccgccgc gtgaatattg cgcgaggcca gaatggcgat gatgaagaag
     7681 ccgaggatcc ccagcagcac gctgtgagaa gtcagattac cgatgctcac cagcgtttcc
     7741 gggttagcga caatcacacc tgcgtttttc agccccatca tgccaataaa cagaccgata
     7801 ccactggtga tgcccacacg tagacttacc gggatgttgg ctatcatcca gtagcgaacg
     7861 cggaaaatcg tcagtaacag cagaccaatc gcgccccaga agattgcgcc catcccgact
     7921 tgccacggca agcccatcgc ctgtacaacg acaaaagcga agaacgcatt caggcccatt
     7981 gccggtgcca gtgcaactgg caggttagca aacagcccca tcataatact gccgaatgca
     8041 gcaatcagac aggtcgtgac gaagacggcg ctggtatcca tgccagcaac gccaagaatt
     8101 tgcgggttaa caaaaacgat gtaaaccatc gtcaggaagg tggtaaaacc ggcgatcact
     8161 tcggtccgtg ccgtcgtgcc atgttcgcgc agtttaaaca cgcgttccag catcccctgg
     8221 ccagaagcct gggttgtgtg ttgttgactc attatctatt tccgaacaag gagggaaaat
     8281 ccgtcgctat cgtataccaa aatgagacaa tatggacggc tgaagataac tttttttcat
     8341 tgtatttgct tatacggcaa cgattgcgtc atgcgaattg gcatgacgaa aacgttaaac
     8401 taacgataaa ggaaagacat gtcccagata gaagcggtat ttttcgactg cgacggtacg
     8461 ctggtcgata gcgaggtcat ttgctctcgc gcctatgtca cgatgttcag ggaatttggc
     8521 attcacgttg acctggaaga gatttttacc cgttttaaag gcgtaaaact ctacgaaatc
     8581 atcaacatca tcagtaaaga acagggcgtg acgatgatcc aggccgatgc cgagcacgtt
     8641 taccgtgcgg aagtggcgcg cctgtttgat agcgagcttg aggtgattgc aggagcgaac
     8701 gaattgctgg ctagtgtgaa agtgccgatg tgcgtcgtct ctaacggccc ggtcagcaag
     8761 atgcagcatt cgcttggtaa gctcaacatg ctgcactact tcccggaaaa actgttcagc
     8821 ggctatgata tccagcgttg gaagcccgat ccggcattaa tgttccatgc ggcaaaagcg
     8881 atgaatgtga acgttgaaaa ctgcattctg gtcgatgact ccagtgccgg tgcgcaatca
     8941 gggatagatg ccggaatgga agtgttttac ttctgcgctg acccgcacaa taaaccgatc
     9001 gttcacccga aagtcaccac ctttacccat ctttcgcaat taccggaact gtggaaggcg
     9061 cgtggttggg atattacggc atagttattc acactccctt cacttactcc acttaaattg
     9121 gcacgcaaag gtaagtaaag ggagtttgat atgtctgttt cacgtcgggt aattcatcac
     9181 ggactgtatt ttgcggtttt agggccgtta attggtgttc tgtttcttgt cctctacata
     9241 ttcttcgcaa aagaaccgct ggttctttgg gtgataatac atccaatttt tctcttattg
     9301 tcgataacta cgggagctat tcctgcgttg ttaaccggtg taatggttgc ctgtctgccg
     9361 gaaaagatcg ggtcacagaa acgttatcgt tgtctggctg gtggcatagg tggagttgtt
     9421 atcaccgaga tctattgcgc tgttatcata catattaagg tcatggcttc ctcagtgttg
     9481 tttgaaaaca ttctttctgg tgacagtctc gttgtccgca tcattcctgc attgctggca
     9541 ggtgtggtga tgagcagaat cattacacgt ctacccggac tggatatttc atgtcctgaa
     9601 acagactctt taagttaagc gggatgtttt atcttttggc tactcaaaag cagacaggat
     9661 gtttctatga ctcaaaatat caggccgtta cccctattca aatatcatcc caagccactg
     9721 gaaacaggcg catttgaaca ggataaaacc gtagagtgcg attgctgtga acaacagacg
     9781 tcagtttatt actcgggtcc cttttattgc gttgatgaag ttgaacatct ctgtccgtgg
     9841 tgtattgcga acggttctgc tgctgaaaag tttgcaggta gttttcagga tgatgccagc
     9901 atcgaaggtg ttgaatttga gtatgatgaa gaggacgatt ttgccggtat taagaacaca
     9961 tatcctgatg aaatgctgaa agagttggtt gaacgcacgc caggttatca tggatggcaa
    10021 caggaattct ggctcgcgca ttgtggcgat ttctgtgctt ttatcggcta tgtgggctgg
    10081 aatgatataa aagatcgcct cgatgaattt gccaaccttg aagaagattg tgagaatttc
    10141 ggtattagaa attctgatct agctaaatgc ctgcaaaagg gtggtgattg tcagggttat
    10201 ctcttccgct gtctccactg cggcaagctg agactgtggg gcgatttttc atagttattt
    10261 atatgatgag aacaggccgg cgcgtaattc acacatccgg ccttattttt aagcttaacc
    10321 gagcgctaat tctgcggcag cggctttatc agcgattacc atcagcgaag gatgcagctg
    10381 caacacggaa gcaggaacat cttcggtaac cggaccttgc agaacatttt tcagtgcctg
    10441 cgctttaccc gcgccactga caattatcag caagtttttc gccgccatga tgcttttcgg
    10501 ccccatcgtc acgtagctgt caggcactaa tgaaaagtcg ccacccaact cgccatgcgc
    10561 cacaatatca accatctctc cctggatcgg gaactccacg gtttgctcat ggaaatgggt
    10621 cgtatttggc aaattgccac aaaaatgacc atctacacct aatcccaaca ccaccaaatc
    10681 caggccacct tcacgcgcca gtttctgatc atgctcgcgg tagttatcaa tagtgagctt
    10741 ctggatattc tcttctttga tccctgcagg ggtgaaaaac agattacgca gattggtaat
    10801 cgttacgcct tccccttctt tgccacgaaa tggaatttca tcgaaattgt agaaatagca
    10861 gttatcgtac cagggcttac ctttaaccag agtgatgaga tattcgtaca tgcctttggg
    10921 cgtgctaccg gcggtaattg ccaggttaac gcgacgcatc tttgacatat aaccaagcag
    10981 atgatgtgcg gcgacacggc tcatttcctg gtaatcttcg gtaatgatca atttcatctt
    11041 aatgccttat tttatttaaa taatttctgt acaaaggctg cataggctgg tcgccagaca
    11101 tccatttcat ggttcagacc gggatattcc tggtaatcaa actttatttt tttctgctca
    11161 agctcagttt tcagcccggc gatatccttg ccggttacga catctttatc gcccacgacc
    11221 acagtaaaat tacgtagttg ctggttaata gctgccggat cgttcagccg ggcagcgacc
    11281 ccttcatctg gtacggtcgt cgtggtaaca ccactgaatg tggccagcca gccaaagctt
    11341 tccagatgat taattcccga taccagtgcc tgatacccac cttgtgaaag ccctgccagt
    11401 gcgcgaccat cggcatcttt acggacatta aaacgcttgc taatcagcgg gataatatcg
    11461 ttcatcagtt cgcgatctgc cgctttagca tttaacggat aaaagacttt acgtctctcc
    11521 tgaggaacga aatcttcggg aataatgccc ttcgcatcgg tttcggtatc cgggatcacc
    11581 accagcatcg gtttaatttt cccttcagcc agcaggttat ccatgatttg cgggatacgc
    11641 ccctgatcaa tagcggaacg tccggtatca ccaaagccgt gatagaaata gagcactggc
    11701 aaaggctcgc ctatgccggt gtatcctggc ggggtccaga catacatctg acgttcggat
    11761 tgcaatgcgt tggagtggta agttatggcg atcaaatcac catgcacaac agaacgtgta
    11821 tccagataac tgcccggtac cagaatcata ctggagttaa cctgacgctg aggcttagtc
    11881 attgccgtgc ctgtatcaat gctgcgtaca ccatcaacat tgaaaaaata ctcgtacaga
    11941 ttgcctttca ggacaggcgt gcgccacgac cagactcccg cttcatcttt ggtcatcggg
    12001 tgaatattgt ccggaaccgg aacacccacc actacggaga cattttttgc cccaggggca
    12061 aagtagcgaa aggtcacgct gttatcggta ttgacctgag tcacatactg tttcaccgga
    12121 atagtgggtg ccgggctggc tggcatatcc gctgctatgg cccattgagc agaaataccg
    12181 ctggcaatag ccagcgttaa agcagcaatt tttatattca tcgtaatatt ccttttatta
    12241 agttccatta ccaccagatt tcagcctggg caccgacagc aaactggtcg tctttattgt
    12301 cttcaaaggt gaagccatcc agttcgtttt ccagagcttt gatatatgta gcgtagaaac
    12361 gaatttccgg gcgcgaggtc aacatactgg tattgacttt aaaggtatgg aagagcgtgg
    12421 ttttataacc agactcatta tatttattgc tattcgcatc tttgttttgc tgggtgaaat
    12481 agcccagttc aacacctgtc tggttatatt ggtcccaaat ataggccggg cgaacaaccg
    12541 cacgaataga ttcgaaatca gaatgtgcgc ctgtttcgta gctataaata tcgttaccga
    12601 aggagtaaac aatcgcgtta gccacaatga aatgatcgcc gatataagct tcgccctgcg
    12661 aagtcagacg aactgcagtt ccgcctgtgt gatcaccata ataacgacca ttaaaggtag
    12721 taaatggact tgcaccagca taacgaccaa agttactggc gatagagtta ttcgcaacca
    12781 ggaaggagaa ttcgttgaag ccacccttat caaatttctg cgttaaagat gtaccaaaca
    12841 tccaggtatc tttccagtca taatacccgt tattatcctg attatctttt tccgatgcgc
    12901 tttcatttgc tgagacataa cgaccgctca ccattaaggt ggctttatcc cataacggga
    12961 tatctttata gcgtaaatca atggtattgg tattaatctg ctgtttgttt tgcaggctgc
    13021 gatcgtaatc atcgacatct tcacgaacca gcgcgatatc aattttaccc ggaccgactt
    13081 tccagttttc cagacctaca cctgcggcag catcggtacg ctgcgttttc cagtcaagca
    13141 tctggatttc aattttcggc gcaccgtgtt tacccaccca gaaatcagcc tctggcgcaa
    13201 agggcaggaa acctttggtg gtaacgtaca tatcagagaa ctgcataaag ttctcgccac
    13261 cggcgttatc gccaaaccag ccagtagagt actgctgacc cacgttacca tccatcatca
    13321 cgatggcatc aacccgtttg ccgttttcgt tgtagacacg ttgttttaac tgcaaatcaa
    13381 accagccgga gtattcgtta ccaaagcggc ccagagaacc aattgcccat gatttaggtg
    13441 aaccatggga ggctgtgccc caaccagaac ggtagtagcc gttgtaacta aagccgattt
    13501 catctttcac aaatttactg aaatctttca gagtcatgga agaataaatc gagcctgtct
    13561 cactggcatt tttctcttca tttttaacca gtacagcatc aggctttgcg gcacgactgg
    13621 tcgggaatgg attggcggca tacccttgat cattcgcact tacgctacga ttcaccgtcg
    13681 ctggcgtata ctttttcttc tcttcatctt tatatttttt cagttcgctt tgcgtttctc
    13741 ttaacgcctt ttctaatagc tcaaggcgtt gttccacggt taatgattca gccaatgatt
    13801 gtgcggaaaa ggctaacggt gccattaata aaatggcaga ggtaataata tttcgtctaa
    13861 acataatatc cctttatggt gcaaagaaag aattaacgca tcgcatccag actgttctga
    13921 atgcgacgat atttaaggtg ctttattggt tattttttta atgatagccc ccgagttttg
    13981 atcacttctg cataccatcc gaagcttttc ttgcgcgttc ttgtgaggct tccttcacca
    14041 ttatcatcac gatccacata aataaagccg tagcgcttag acatttgtga atgagatgca
    14101 ctgactaaat caattggccc ccaactggtg taccccataa tatccacacc atcggcaatc
    14161 gcttcattta cctgtaccag gtgatcattt aaataggcaa ttcgataatc gtcctgtatc
    14221 gaaccatcca cttcaacgct gtcttttgcg cctaatccgt tctcgacaat aaataacggt
    14281 ttttgataac gatcccaaag cgtatttaac agaatccgta atccaaccgg atcaatttgc
    14341 cacccccact ctgaactttt cagatgcgga tttgggatca tattcagtat gttgccctgc
    14401 gcatttttat taatgctttc gtcgtgggaa acacaaccgg tcatgtaata actaaaagag
    14461 atgaaatcta cggtatgttt taaatcttct gcgtcacttt cagtcatctc aatggtgata
    14521 ttgtggtcgc ggaagaaacg ctgcatatag ccgggatact gaccacgcgc ctgaacatca
    14581 ccaaagaaca tccagcgccg gttctcttcc atggcctgca acatatcctg tggctggcag
    14641 gtgagggggt aaaccagccc accgagaagc atattgccaa ttttcgcttc ggggatcagg
    14701 ctatgacagg ctttaactgc ccgcgcactg gcaaccagtt gatgatggat cgcctgataa
    14761 acttccgcct cgccactctc ttctgccagc cccacgcccg tgaatggcgc gtgtaatgac
    14821 atgttgattt cattaaatgt cagccataac acaactttat gttggtagcg ggtaaagacc
    14881 gtgcgtgcgt aatgctcgaa gtgatcgatg accgcccgat tagcccaacc gccgtagttt
    14941 ttcaccagcc catatggcat ttcgtaatgg gataacgtta ccagcggctt gatccccgcc
    15001 tgcgccattt catcaaacag ccgctcgtaa aacgctaacc ccgcttcatt cggttcggct
    15061 tcgtcgccct gagggaaaat tcgcgcccag gcaatggaaa tacgcagaca ggtgaagccc
    15121 atctcggcaa ataacgcgat atcttccggg taacggtgat aaaaatcgat ggcgacatct
    15181 ttgatattct ctttccccag gatgcgcggt tccatttttc ccattacgcc atgaggctgt
    15241 aaatctgagg tcgtgatccc tttgccatct tcctgccatg cgccttccac ctgattggca
    15301 gctgttgcac caccccaaag aaatgtttct ggaaatgctt tcataattaa ctccttttat
    15361 cgttagcgaa tgatggataa cagcggctca ccagcgttta tctgcaccgt gccgtggggt
    15421 aatacgtccg taaaatcatc gctattactg attaataccg gcgtcgtcag atcaaatccg
    15481 gcctcgcgaa tagcagggat atcaaaagaa atcagccgat cgcctgtatt gaccttgtca
    15541 cccacgttga cgtgagcgga aaagaatttg ccgtccagtt ttacggtgtc gataccgaca
    15601 tgaatcagga tctccacgcc atcatctgac tcaatgccaa tggcgtgtaa tgtggcgaac
    15661 aacgaagcaa ttcgacccgc caccggagaa cgcacttcac caacagaggg cagaatggca
    15721 atacctttac ccaacaggcc actggcaaac gtggtatcag cgacgtgaat gagcggcaca
    15781 atatctcccg tcatcggtga acagataccg ccctgctcag gtgtaataat ctctggtgtt
    15841 ttctcttgct gggcaacttg cgctggctga cgtttagcgg tgatgaaatg aagcatcacc
    15901 gtaccgacaa atgcgcaacc gatggcaatg acaccaccaa taacgctggc ccatacggtg
    15961 aaatcaatcc ccgttgacgg gatggtttgc atgaaggtga aaatacctgg caaaccaaag
    16021 gagtaaactt tcgtttgcgc gtagccaatg atggtggccc ccaatgcccc acttatgcag
    16081 gcgataacga aggggtactt acgcggcagg ttgacgccat atactgccgg ttcggtgata
    16141 ccaaacagcc ccgtcaacgc cgccgatccc gctaccactt ttttctgcgc atcgcgttcg
    16201 cagaggaaga cgccgagcgc cgccccgact tgcgccataa tggcgggcat taacagcggg
    16261 atcatggtgt cgtagcccag cacggtgaag ttattgataa ttaaaggtat caaaccccaa
    16321 tgcagaccaa acatcacaaa gatttgccag aagccgccca ttaccgcgcc tgcaaatgca
    16381 ggaaccgcct gataaagcca gagataaccg gcagcaatca gttcacttat ccaggttgat
    16441 agcggcccca ccagcagaaa tgtgatgggc gtgatgacca tcagacatag caagggtgtg
    16501 aagaaatttt tgattgccga aggtaaccac gcattaagtc ggcgttccag aatgctgcac
    16561 aaccaggcag aaaaaataat gggaataacc gatgacgagt aattcaacaa tgtgaccgga
    16621 atacccagga aatccaggcc cagcgcatcc actttttgcc cgttctcgaa ggcagtcaga
    16681 attaatggat gcactaacgc tccgccaatc accatggcag taaatggatt gccgctgaag
    16741 cgtttccctg cggtgtagcc caggattatc gggaagaacc aaaacaaggc atcactggcg
    16801 ctaaataaaa ttaaataagt accactttgt tcggtcgtcc actgaaaagt gagtgccaga
    16861 gccaacatac ctttcaggat cccggttgcc gccatcaaac cgatcagagg cgtaaaaata
    16921 cctgaaataa cataaacaaa gcggtttaac agattacctt tatcatcatt ttccggtgcc
    16981 tgttgcgctt tttcgccaag gcctgccacg ctgttaaccg ccaggaagac atcggccaca
    17041 tggttaccta tgacaacctg aaactggcca ccgctttcca ccaccataat aataccgggg
    17101 gtctttttca gtacctcagc ttgcgctttg ctttcatcct ttaacttaaa acgtaatcgc
    17161 gttgcacaat gcatcagact cacaatgtta tctgcgcccc cgactcctgc gactattgtt
    17221 ctggctaact ccgtcataac ttgccctcta ccgctttgcg gcaaaactca aaaaaaaacc
    17281 tgaaaaaaac ggcctgacgt gaatcaagca atttttttca ggttttgccc gcttagtgcg
    17341 gtaacaatcc tttattcagt aataatattt cagtgttctt tgcgcacgcg ctctatattt
    17401 atggctaaaa acataatctc tgcaggtgag attttacgtt gatactgcaa accaataaaa
    17461 atggcgatcc gctccgcaca ttgccatgct tgcgggtaat tttgctttac tgcttattgt
    17521 aatgattcat cactatcgtt aatcgatgca tgttcaataa tacgccagga taaaaatttc
    17581 agatgcgtaa ccagtcgctg ataactcaag ctttcttcct ggtaattaag gctgaactga
    17641 aattttatta attgcagcat ttctcgcatt aattgcgtga cacctgcaac atcctccata
    17701 tttccgctca tttgggcact gaccagatgc atggcaataa agcccacttc atctttcggt
    17761 aactgcacgc ccaaccgttt atcaataatg gttaacgctt cttcccctag ctggaactct
    17821 ttcgggtaaa gtcgctggat atcccacagc agcgggttgg gcagtagcac gttttgctga
    17881 aagcgtttaa tcgcaaactg gcaatggtca gttagcgaga tataaatact gtcctgcaac
    17941 tttcccagac gctcctgcgc cagagagata atacgatcac aggttgccat cacctcaaga
    18001 ggcatatgac ttaagagttc gcttaatcgc ccgttcagtt catgactgct caaggcatac
    18061 tctttttcta ttccacttga gttaattctt tcgcctgggc gtttttgaaa gccaattccg
    18121 cgccccatga cgactttttc ccgctgttga tcatcaataa ccaccacaac attattgttg
    18181 agaattttgg tgatttgcat gttcatagca aggacctttt ttataaacaa aaaaacccga
    18241 cttcaccagt attctctggt tatgtcaggt tttgcctgcg aatgcagtaa caatccagtc
    18301 attaattaat ggtttttata acgaacatcc aggttcgaaa attaatttag ttgcgtgcag
    18361 aaaaaatagc aatgctctat ttataaaagt atgaccatgc tcgcagttat taattttgtg
    18421 taattttagg
//
LOCUS       DAPOXO010000096        17585 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPOXO010000096 DAPOXO010000000
VERSION     DAPOXO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17585
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.096"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..353
                     /gene="wcaE"
                     /locus_tag="ROH59_004116"
     CDS             <1..353
                     /gene="wcaE"
                     /locus_tag="ROH59_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaE"
                     /protein_id="HDX4806533.1"
                     /translation="AKPGWYIYHSLPASHQAIFFPVSGLKKWRYDLEYKVSSDYALAA
                     KMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQILHVPGFWAELSWHLR
                     QRTTSKTKALYNKS"
     gene            369..917
                     /gene="wcaF"
                     /locus_tag="ROH59_004117"
     CDS             369..917
                     /gene="wcaF"
                     /locus_tag="ROH59_004117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaF"
                     /protein_id="HDX4806534.1"
                     /translation="MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRA
                     FLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDEVNLYTLGEITIGAHSVISQ
                     KSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKS
                     LPANVVCRGHPAVVIRKRVETE"
     gene            944..2065
                     /gene="gmd"
                     /locus_tag="ROH59_004118"
     CDS             944..2065
                     /gene="gmd"
                     /locus_tag="ROH59_004118"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HDX4806535.1"
                     /translation="MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRF
                     EGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWK
                     PEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES"
     gene            2068..3033
                     /gene="fcl"
                     /locus_tag="ROH59_004119"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
     CDS             2068..3033
                     /gene="fcl"
                     /locus_tag="ROH59_004119"
                     /gene_synonym="wcaG"
                     /gene_synonym="yefB"
                     /EC_number="1.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HDX4806536.1"
                     /translation="MSKQRIFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDS
                     RAVHDFFASESIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKL
                     LFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMA
                     AASIHVMELAHEVWQENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG"
     gene            3036..3515
                     /gene="gmm"
                     /locus_tag="ROH59_004120"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
     CDS             3036..3515
                     /gene="gmm"
                     /locus_tag="ROH59_004120"
                     /gene_synonym="nudD"
                     /gene_synonym="wcaH"
                     /gene_synonym="yefC"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HDX4806537.1"
                     /translation="MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGY
                     WFVPGGRVQKDETLEAAFERLTMAELGLRLPITAGQFYGVWQHFYDDNFSGSDFTTHY
                     VVLGFRFRVAEEELLLPDEQHDDYRWLTPDALLASDNVHANSRAYFLAEKRAGVPGL"
     gene            3512..4735
                     /gene="wcaI"
                     /locus_tag="ROH59_004121"
     CDS             3512..4735
                     /gene="wcaI"
                     /locus_tag="ROH59_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis fucosyltransferase
                     WcaI"
                     /protein_id="HDX4806538.1"
                     /translation="MKILVYGINYSPELTGIGKYTGEMVEWLAAQGHEVRVITAPPYY
                     PQWQVGENYSAWRYKREEGAAMVWRCPLYVPKQPSTLKRLLHLGSFAVSSFFPLMAQR
                     RWKPDRIIGVVPTLFCTPGMRLLAKLSGARTVLHIQDYEVDAMLGLGLAGKGKGGKVA
                     QLATAFERSGLHNVDNVSTISRSMMNKAIEKGVAAENVIFFPNWSEIARFQHVADADV
                     DALRNQLGLPDNKKIILYSGNIGEKQGLENVIEAADRLRDEPLIFAIVGQGGGKARLE
                     KMAQQRGLRNMQFFPLQSYDALPALLKMGDCHLVVQKRGAADAVLPSKLTNILAVGGN
                     AVITAEAHTELGQLCETFPGIAVCVEPESVEALVAGIRQALLLPKHNTVAREYAERTL
                     DKENVLRQFINDIRG"
     gene            4738..6174
                     /gene="cpsB"
                     /locus_tag="ROH59_004122"
     CDS             4738..6174
                     /gene="cpsB"
                     /locus_tag="ROH59_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="HDX4806539.1"
                     /translation="MAQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTT
                     ICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAA
                     KRHSPENDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGY
                     IRRGEVSAGEQDTVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELK
                     KYRPDILDACEKAMSAVDPDLDFIRVDEEAFLACPEESVDYAVMERTADAVVVPMDAG
                     WSDVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTK
                     DAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITV
                     KPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKI
                     PLDLIEVRSGSYLEEDDVVRFADRYGRV"
     gene            6279..7649
                     /gene="cpsG"
                     /locus_tag="ROH59_004123"
                     /gene_synonym="manB"
     CDS             6279..7649
                     /gene="cpsG"
                     /locus_tag="ROH59_004123"
                     /gene_synonym="manB"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis phosphomannomutase
                     CpsG"
                     /protein_id="HDX4806540.1"
                     /translation="MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLF
                     GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINR
                     VEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEARTRTL
                     LTLLNE"
     gene            7705..9099
                     /gene="wcaJ"
                     /locus_tag="ROH59_004124"
     CDS             7705..9099
                     /gene="wcaJ"
                     /locus_tag="ROH59_004124"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HDX4806541.1"
                     /translation="MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSF
                     LYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSVIFSAGLVAFN
                     NDFDTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLM
                     ESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGA
                     RVKKLVHQLADTTCSVLLIPDVFTFNILHSRIEEMNGVPVVPLYDTPLSGVNRLIKRA
                     EDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVME
                     NDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYR
                     QLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIV
                     FLTVFKGFVNKAAY"
     gene            9101..10579
                     /gene="wzxC"
                     /locus_tag="ROH59_004125"
     CDS             9101..10579
                     /gene="wzxC"
                     /locus_tag="ROH59_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid undecaprenyl disphosphate flippase
                     WzxC"
                     /protein_id="HDX4806542.1"
                     /translation="MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLL
                     TVSLVIIALADTLSDFGIANSIIQRKEISHLELTTLYWLNVGLGIVVCVAVFLLSDLI
                     GDLLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTFTV
                     VSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTA
                     DSIINYLNTNLSTLVLARILGAGVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQ
                     DDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKWSSIIPVLQLLCIVG
                     LLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIIIGGQMAGAIGVTLGFLLVQI
                     INTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTLVVSYALGIVLKGQLALGMLLA
                     VQIATGVLAFVVMIVLSRHPLVVEVKRQFCRSEKMKMLLRAG"
     gene            11048..12328
                     /gene="wcaK"
                     /locus_tag="ROH59_004126"
     CDS             11048..12328
                     /gene="wcaK"
                     /locus_tag="ROH59_004126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis pyruvyl transferase
                     WcaK"
                     /protein_id="HDX4806543.1"
                     /translation="MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPV
                     SSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNI
                     AIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGP
                     FQDKQFNQLANYVFGHCDALILRESVSLDLMKRSNITTAKVEHGVDTAWLVDHHTEDF
                     TASYAVQHWLDVAAQQKAVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQV
                     IALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGT
                     RLHSAIISMNFATPAIAINYEHKSAGIMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQ
                     LPALNARLNEAVSRERQTGMQMVQSVLERIGEVK"
     gene            12325..13545
                     /gene="wcaL"
                     /locus_tag="ROH59_004127"
     CDS             12325..13545
                     /gene="wcaL"
                     /locus_tag="ROH59_004127"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaL"
                     /protein_id="HDX4806544.1"
                     /translation="MKVGFFLLKFPLSSETFVLNQITAFIDMGFEVEIVALQKGDTQN
                     THAAWTKYNLAARTRWLQDEPTGKVAKLRHRASQTLRGIHRKNTWQALNLKRYGAESR
                     NLILSAICGQVATSLHADVFIAHFGPAGVTAAKLRELGVIRGKIATIFHGIDISSREV
                     LNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTRFSPRPVKA
                     PATPLEIISVARLTEKKGLHVAIEACRQLKEQGVAFRYRILGIGPWERRLRTLIEQYQ
                     LEDVVEMPGFKPSHEVKEMLDDADVFLLPSVTGADGDMEGIPVALMEAMAVGIPVVST
                     LHSGIPELVEADKSGWLVPENDARALAQRLAAFSQLDSDELAPVVKRAREKVEHDFNQ
                     QVINRELASLLQAL"
     gene            13556..14950
                     /gene="wcaM"
                     /locus_tag="ROH59_004128"
     CDS             13556..14950
                     /gene="wcaM"
                     /locus_tag="ROH59_004128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HDX4806545.1"
                     /translation="MPFKKLSRRTFLTASSVLAFLHTPFARALPAQQSVNINDYNPHD
                     WIASFKQAFSEGQTVVVPAGLVCDNINTGIFIPPGKTLHILGSLRGNGKGRFVLQDGS
                     QVTGEGGGSMHNITLDVRGSDCTIKGLAMSGFGPVTQIYIGGKNKRVMHNLTIDNLTV
                     SHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHVIERINCT
                     NGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIK
                     ARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNF
                     RVNDIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFMRNINV
                     MQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRINHHIV
                     NVEKINFRLPERRE"
     gene            15125..16018
                     /gene="galF"
                     /locus_tag="ROH59_004129"
     CDS             15125..16018
                     /gene="galF"
                     /locus_tag="ROH59_004129"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalF"
                     /protein_id="HDX4806546.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLELRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDNASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQAVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     gene            16391..17476
                     /gene="rfbB"
                     /locus_tag="ROH59_004130"
     CDS             16391..17476
                     /gene="rfbB"
                     /locus_tag="ROH59_004130"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDX4806547.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYFFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSGLDDEKKKNFRFHHISTDEVYGDLPHPDEVNSNETLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNSLEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVFTICDL
                     LDEIVPKEKSYREQITYVTDRPGHDRRYAIDAEKIGRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            17476..>17585
                     /locus_tag="ROH59_004131"
     CDS             17476..>17585
                     /locus_tag="ROH59_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar nucleotide-binding protein"
                     /protein_id="HDX4806548.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDY"
BASE COUNT         4261 a         4313 c         4881 g         4130 t
ORIGIN      
        1 gcgccaaacc gggttggtat atttaccaca gcctgcccgc cagtcatcag gcgatatttt
       61 tcccggtgtc cggcttgaag aaatggcgtt atgacctgga gtataaagtt tcttccgatt
      121 acgcgctggc ggccaaaatg tataaagccg gttatgcatt taaaaaactc aatggcctgg
      181 tgtctgaatt ttctatgggt ggggtatcta ccaccaataa tatggaattg tgtgctgacg
      241 ccaaaaaagt ccaacggcaa atattgcacg tgcctggctt ttgggctgaa ttatcctggc
      301 atttacgcca acgtacgacc tcaaagacga aagccttata taacaaaagc tgaatataag
      361 ggaaaacgat gcaggattta agtggattct cggtgccgaa agggttccgg ggtggcaacg
      421 ctattaaagt gcaattgtgg tgggcagtac aggcaacaat atttgcctgg tcgccacaag
      481 tattgtatcg ctggcgggca tttttattac gtttattcgg cgcaaaaata ggaaaaaacg
      541 tagtcattcg tccgtcagta aaaattacct atccgtggaa attaacgtta ggtgattacg
      601 cgtgggtcgg cgatgaggtc aatttatata ccctcggtga aataaccatt ggcgcacatt
      661 cggtgatatc gcaaaaaagt tatttatgca ctggtagcca cgaccatgca agtcaacatt
      721 tcaccattaa cgccacgcct attgtgattg gcgagaaatg ctggctggca accgatgtct
      781 ttgttgcccc tggcgtcacg atcggcgacg gcaccgtcgt gggtgcgcga agcagtgttt
      841 ttaaatcgct tccggcaaat gtggtttgtc gggggcaccc cgcagtggtg atacgcaaac
      901 gcgttgaaac tgaataaatt caaaaaatac agaggaataa gacatgtcaa aagtcgctct
      961 catcaccggt gtaaccggac aagacggttc ttacctggca gagtttctgc tggaaaaagg
     1021 ttacgaggtg catggtatta agcgtcgtgc atcgtcattc aacaccgagc gcgtggatca
     1081 catttatcag gatccgcaca cctgcaaccc gaaattccat ctgcattatg gcgacctgag
     1141 tgatacctcc aacctgacgc gcattttgcg tgaagtgcag ccggatgaag tgtacaacct
     1201 gggggcaatg agccacgttg cggtttcttt tgagtcaccg gaatataccg cagacgtcga
     1261 tgcgatgggt acgctgcgcc tgctcgaggc gatccgcttc ctcggtctgg aaaagaaaac
     1321 ccgtttctat caggcttcta cttctgaact gtacggtctg gtgcaggaaa ttccgcagaa
     1381 agagaccacg ccgttctacc cgcgatctcc gtatgcggtt gccaaactgt acgcctactg
     1441 gatcaccgtt aactaccgcg aatcctacgg catgtacgcc tgtaacggta ttctcttcaa
     1501 ccatgaatcc ccgcgccgtg gcgagacttt cgttacccgc aaaatcaccc gcgcaatcgc
     1561 caacatcgcc caggggctgg agtcgtgcct gtatctcggc aatatggatt ccctgcgtga
     1621 ctggggccac gccaaagact acgtaaaaat gcagtggatg atgctgcaac aggaacaacc
     1681 ggaagatttc gttattgcca ccggcgttca gtactccgtg cgtcagttcg tggaaatggc
     1741 ggcggcacaa ctgggcatca aactgcgctt tgaaggcacg ggtgttgaag agaagggcat
     1801 tgtggtttcc gtcaccgggc atgacgcgcc gggcgttaaa ccgggtgatg tgattatcgc
     1861 cgttgacccg cgctacttcc gtccggcaga agttgaaacg ctgctcggtg acccgaccaa
     1921 agcgcacgaa aaactgggct ggaaaccgga aatcaccctc agagagatgg tgtctgaaat
     1981 ggtggctaat gaccttgaag cggcgaaaaa acactctctg ctgaaatctc acggctacga
     2041 cgtggcgatc gcgctggagt cataagcatg agtaaacaac gcatttttat tgctggccat
     2101 cgcgggatgg tcggttccgc catcaggcgg cagctcgaac agcgcggtga tgtggagctg
     2161 gtattacgca cccgcgatga actgaacctg ctggacagcc gcgcggtgca tgatttcttt
     2221 gccagcgaaa gcattgacca ggtctatctg gcggcggcga aagtgggtgg tattgttgcc
     2281 aacaacacgt atccggcaga tttcatctac cagaacatga tgattgagag caacatcatt
     2341 cacgccgcgc atcagaacga cgtgaacaaa ctgctgtttc tcggatcgtc ctgcatctac
     2401 ccgaaactgg caaaacagcc gatggcagaa agcgagttgt tgcagggcac gctggagccg
     2461 accaacgagc cttacgccat tgccaaaatc gccgggatca aactgtgtga atcttacaat
     2521 cgccagtacg gacgggatta ccgctcagtc atgccaacca acctgtacgg gccacacgac
     2581 aacttccacc cgagtaattc gcatgtgatc ccagcattgc tgcgtcgctt ccatgaggcg
     2641 acggcacaga atgcgccgga cgtggtggtg tggggcagcg gtacgccgat gcgcgaattt
     2701 ctacacgttg atgatatggc agcggcgagc attcatgtca tggagctggc acacgaagtc
     2761 tggcaggaga acacccagcc gatgctgtcg cacattaacg tcggcacggg cgttgactgc
     2821 actatccgtg agctggcgca aaccatcgcc aaagtggtgg gttacaaagg tcgggtggtt
     2881 tttgatgcca gcaaaccgga tggcacgccg cgcaaactgc tggatgtgac gcggctgcat
     2941 cagcttggct ggtatcacga aatctcactg gaagcggggc ttgccagcac ttaccagtgg
     3001 ttccttgaga atcaagaccg ctttcggggg taatgatgtt tttacgtcag gaagactttg
     3061 ccacggtagt gcgctccact ccgcttgtct ctctcgactt tattgtcgag aacagtcgcg
     3121 gcgagtttct gcttggcaaa agaaccaacc gcccggcgca gggttactgg tttgtgccgg
     3181 gagggcgcgt gcagaaagac gaaacgctgg aagccgcatt tgagcggctg acgatggcgg
     3241 aactggggtt gcgtctgccg ataacagcag gccagtttta cggtgtctgg cagcactttt
     3301 atgacgataa cttctccggc tcggatttta ccactcacta tgtggtgctc ggttttcgct
     3361 tcagagtagc ggaggaagag ctgttactgc cggatgagca gcatgacgat taccgctggc
     3421 tgacgccgga cgcgttgctc gccagtgaca atgttcacgc taacagccgc gcctattttc
     3481 tcgctgagaa gcgtgccgga gtacccggat tatgaaaata ctggtctacg gcattaacta
     3541 ctcgccggag ttaaccggca tcggcaaata caccggcgag atggtggaat ggctggcggc
     3601 acaaggtcat gaggtgcggg tcattaccgc gccgccttac tacccgcagt ggcaggtggg
     3661 cgagaactat tccgcctggc ggtacaaacg ggaagagggg gccgccatgg tgtggcgctg
     3721 cccgctgtac gtgccaaaac agccgagcac tctgaaacgc ctgttgcatc tcggcagttt
     3781 tgccgtcagc agtttctttc cactgatggc gcaacgtcgc tggaagccgg atcgcattat
     3841 cggcgtagtg ccaacgctgt tttgcacgcc gggaatgcgc ctgctggcga aactctctgg
     3901 tgcgcgtacc gtgctgcata ttcaggatta cgaagtggac gccatgctgg ggctgggcct
     3961 tgccggaaaa ggcaaaggcg gcaaagtggc acagctggcg acggcgttcg aacgtagcgg
     4021 actgcataac gtcgataacg tctccacgat ttcgcgttcg atgatgaata aagccatcga
     4081 aaaaggcgtg gcggcggaaa acgtcatttt cttcccaaac tggtcggaaa tcgcccgttt
     4141 tcagcatgtc gcagacgccg atgttgatgc ccttcgtaac cagcttggcc tgccggataa
     4201 caaaaaaatc attctttact ccggcaatat tggtgaaaag caggggctgg aaaacgttat
     4261 tgaagctgcc gatcgcctgc gcgatgaacc gcttattttt gccattgtcg ggcagggcgg
     4321 cggcaaagcg cggctggaaa aaatggcgca gcagcgtgga ctgcgcaaca tgcaattttt
     4381 tccgctgcaa tcgtatgacg ctttacccgc actgctgaag atgggggatt gccatctggt
     4441 ggtgcaaaaa cgcggcgcgg cagatgccgt attgccgtcg aaactgacca atattctggc
     4501 ggtaggcggt aacgcggtga ttaccgcaga agcccacacc gaactggggc agctttgcga
     4561 aacctttccg ggcattgcgg tttgcgtgga accggaatcg gtcgaggcgc tggtggcggg
     4621 gattcgtcag gcgctcctgc tgcccaaaca caacacggtg gcacgtgaat atgccgaacg
     4681 cacgctcgat aaagagaacg tgttacgtca atttataaat gatattcggg gataattatg
     4741 gcgcagtcga aactctatcc agttgtgatg gcaggtggct ccggtagccg cttatggccg
     4801 ctttcccgcg tactttaccc caagcagttt ttatgcctga aaggcgatct caccatgctg
     4861 caaaccacca tctgccgcct gaacggcgtg gagtgcgaaa gcccggtggt gatttgcaat
     4921 gagcagcacc gctttattgt cgcggaacag ctgcgtcaac taaataaact caccgagaac
     4981 attattctcg aaccggcggg gcgtaacacc gcacctgcca ttgcgctggc ggcgctggcg
     5041 gcaaaacgtc atagcccgga gaacgaccca ttaatgctgg tgctggcggc ggatcatgtg
     5101 attgccgatg aagacgcgtt ccgtgccgcc gtgcgtaatg ccatgccgta tgccgaagcg
     5161 ggcaagctgg tgaccttcgg cattgtgccg gatctacctg aaaccggata tggctatatt
     5221 cgtcgcggtg aagtgtcggc gggtgagcag gatacggtgg cctttgaagt ggcgcagttt
     5281 gtcgaaaaac cgaatctgga aaccgcgcag gcctatgtgg caagtggcga atattactgg
     5341 aacagcggta tgttcctgtt ccgtgccgga cgttatctcg aagaactgaa aaagtatcgt
     5401 ccggatattc tcgatgcctg tgaaaaagcg atgagcgccg tcgatccgga tctcgatttt
     5461 attcgtgtgg atgaagaggc gtttctcgcc tgtccggaag agtcggtaga ttacgcggtc
     5521 atggaacgca cggcagatgc cgttgtggtg ccgatggatg cgggctggag tgatgtcggt
     5581 tcctggtcct ctttatggga gatcagtgcc cacaccgccg agggcaacgt ttgccatggc
     5641 gatgtgatta atcacaaaac tgaaaacagc tatgtgtatg ccgaatctgg cctggtcacc
     5701 accgtcgggg tgaaagattt ggtggtagtg cagaccaaag atgcagtgct gattgctgac
     5761 cgtaacgcgg tgcaggatgt gaaaaaagtg gtcgagcaga tcaaagctga tggtcgccat
     5821 gagcatcggg tgcatcgcga agtgtatcgt ccgtggggca aatatgactc tatcgacgcg
     5881 ggcgaccgct accaggtgaa acgcatcacc gtgaaaccgg gcgaagggtt gtcggtacag
     5941 atgcatcatc accgcgcgga acactgggtg gttgtcgcgg gaacggcaaa agtcactatc
     6001 gacggtgata tcaaactgct tggtgaaaac gagtccattt atattccgct gggggcgacg
     6061 cattgcctgg aaaacccggg gaaaattccg ctcgatttaa ttgaagtgcg ctccggctct
     6121 tatctcgaag aggatgatgt ggtgcgcttc gcggatcgct acggacgggt gtaaacgtcg
     6181 catcaggcaa tgaatgcgaa accgcgatgt aaataacgac aaaaacaaaa ttggccgttt
     6241 cggtcagggc caactattgc ctgaaaaagg gtaacgatat gaaaaaatta acctgcttta
     6301 aagcctatga tattcgcggg aaattaggcg aagaactgaa tgaagatatc gcctggcgca
     6361 ttggtcgcgc ctatggcgaa tttctcaaac cgaaaaccat tgtgttaggc ggtgatgtcc
     6421 gcctcaccag cgaaacctta aaactggcgc tggcgaaagg tttacaggat gcgggcgtcg
     6481 acgtgctgga tatcggcatg tccggcaccg aagaaatcta tttcgccacg ttccatctcg
     6541 gcgtggatgg cggcattgaa gttaccgcca gccataaccc gatggattac aacggcatga
     6601 agctggtgcg cgaaggggct cgcccgatca gcggcgatac cggactgcgc gacgtccagc
     6661 gtctggcaga agccaacgac tttcctcccg tcgatgaaac caaacgcggt cgctatcagc
     6721 aaatcaatct gcgtgacgct tacgttgatc acctgttcgg ttatatcaac gtcaaaaacc
     6781 tcacgccgct caagctggtg attaactccg ggaacggcgc ggcgggtccg gtggtggacg
     6841 ccattgaagc ccgctttaaa gccctcggcg caccggtgga gttaatcaaa gtgcataaca
     6901 cgccggacgg caatttcccc aacggtattc ctaacccgct actgccggaa tgtcgcgacg
     6961 acacccgcaa tgcggtcatt aaacacggcg cggatatggg cattgctttt gatggcgatt
     7021 ttgaccgctg tttcctgttt gacgaaaaag ggcagtttat cgagggttac tacattgtcg
     7081 gtttgctggc agaagcgttc ctcgaaaaaa atcccggcgc gaagatcatc cacgatccac
     7141 gtctctcctg gaacaccgtt gatgtggtga ctgccgcagg cggcaccccg gtaatgtcga
     7201 aaaccggaca cgcctttatt aaagaacgta tgcgcaagga agacgccatc tacggtggcg
     7261 aaatgagcgc ccaccattac ttccgtgatt tcgcttactg cgacagcggc atgatcccgt
     7321 ggctgctggt cgccgaactg gtgtgtctga aaggaaaaac gctgggcgaa ctggtgcgcg
     7381 accggatggc ggcattcccg gcaagcggtg agatcaacag caaactggcg caacccgttg
     7441 aggcgattaa ccgcgtggaa cagcatttta gccgtgaggc actggcggtg gatcgtaccg
     7501 atggcatcag catgaccttt gccgactggc gctttaatct gcgctcctcc aacaccgaac
     7561 cggtggtgcg gttgaatgtg gaatcacgcg gtgatgtgcc gctgatggaa gcgcgaacgc
     7621 gaactctgct gacgttgctg aacgagtaat gtcggatctt cccttacccc cactgcgggt
     7681 aaggggctaa aaacaggaac aacgatgaca aatctaaaaa agcgcgagcg agcgaaaacc
     7741 aatgcatcgt taatctctat ggtgcaacgc ttttcagata tcaccatcat gtttgccggg
     7801 ctatggctgg tttgcgaagt gagcggactg tcattcctct acatgcacct gttggtggcg
     7861 ctgattacgc tggtggtgtt ccagatgctg ggcggcatca ccgattttta tcgctcatgg
     7921 cgcggtgttc gggcagcgac agaatttgcc ctgttgctac aaaactggac gttaagcgtg
     7981 attttcagcg ccggactggt ggcgttcaac aatgatttcg acacgcaatt gaaaatctgg
     8041 ctggcgtggt atgggctgac cagcatcgga ctggtggttt gccgttcatg tattcgtatt
     8101 ggggcgggct ggctgcgtaa tcatggctat aacaagcgca tggtcgcggt ggcgggggat
     8161 ttagccgccg gacaaatgct gatggagagc ttccgtaatc agccgtggtt agggtttgaa
     8221 gtggtgggcg tttaccacga cccgaaaccg ggtggcgttt ctaacgactg ggcgggtaat
     8281 ctgcaacagc tggtcgagga tgcgaaagcg ggcaagattc ataacgtcta tatcgcgatg
     8341 cagatgtgcg acggcgcgcg agtgaaaaaa ctggtccatc aactggcgga caccacctgt
     8401 tcggtgctgc tgatccccga tgtctttacc ttcaacattc tccattcccg tatcgaagag
     8461 atgaacggcg taccggtggt gccgctgtat gacacgccgc tttccggggt taaccgcctg
     8521 ataaaacgtg cggaagatat tgtgctggcg acgcttatcc tgctgctgat ctccccggtg
     8581 ctgtgctgca ttgcgctggc ggtgaaactg agctcaccgg ggccggttat tttccgccag
     8641 actcgctacg gcatggatgg caagccgatc aaagtgtgga agttccgttc catgaaagtg
     8701 atggagaacg acaaagtggt gacccaggcg acgcagaacg atccgcgcgt caccaaagtg
     8761 gggaactttc tgcgccgcac ctcgctggac gaattgccgc agtttatcaa tgtgctgact
     8821 ggcgggatgt cgattgtcgg tccgcgtccg cacgcggtgg cgcataacga acagtatcgc
     8881 cagctcattg aaggctacat gctgcgccat aaagtgaaac cgggcattac cggctgggcg
     8941 cagattaacg gctggcgcgg cgaaaccgac acgctggaga aaatggaaaa acgcgtcgag
     9001 ttcgaccttg agtacatccg cgaatggagc gtctggttcg atatcaaaat cgttttcctg
     9061 acggtattca agggcttcgt taacaaagcg gcatattgat atgagcttac gtgaaaaaac
     9121 catcagcggc gcgaagtggt cggcgattgc cacggtgatc atcatcggcc tcggtctggt
     9181 gcaaatgact gtgctggcgc ggattataga taaccaccag ttcggtttgc ttaccgtgtc
     9241 gctggtgatc atcgcgctgg cagatacgct ttctgacttc ggtatcgcta actccattat
     9301 tcagcgaaaa gaaatcagcc accttgaact caccacgctg tactggctga acgtcgggct
     9361 ggggatcgtg gtgtgcgtgg cggtgttttt gttgagtgat ctcatcggcg acttgctgaa
     9421 taacccggac ctggcaccgt tgattaaaac attgtcgctg gcgtttgtgg tgatccccca
     9481 cgggcaacag ttccgcgcgt tgatgcaaaa ggagctggag ttcaacaaaa tcggcatgat
     9541 cgaaaccagc gcggtgctgg cgggctttac ttttacggtg gttagcgccc atttctggcc
     9601 gctggcgatg accgcgattc tcggttatct ggtcaatagt gcggtgagaa cgctgctgtt
     9661 tggctacttt ggccgcaaaa tttatcgccc cggtctgcat ttctcgctgg cgtcggtggc
     9721 accgaactta cgctttggtg cctggctgac ggcggacagc atcatcaact atctcaacac
     9781 caacctttca acgctggtgc tggcgcgtat tctcggcgcg ggcgtggctg ggggatacaa
     9841 cctggcgtac aacgtggccg ttgtgccacc gatgaagctg aacccgatca tcacccgcgt
     9901 gttgtttccg gcgttcgcca aaattcagga cgatacagaa aagctgcgcg tcaacttcta
     9961 caagctgctg tcggtggtgg ggattatcaa ctttccggcg ctgctggggc taatggtggt
    10021 gtcgaataac tttgtaccgc tggtatttgg cgaaaagtgg agcagcatta ttccggtgct
    10081 gcaattgctg tgtattgtgg ggctactgcg ctccgtgggt aacccgattg gttcgctgct
    10141 gatggcgaaa gcgcgggtcg atatcagctt taaattcaac gtattcaaaa cctttctgtt
    10201 tattccggca atcatcattg gtgggcagat ggcgggcgca atcggcgtca cgcttggctt
    10261 cctgctggtg cagattatca acaccattct gagctatttc gtgatgatta aaccggtgct
    10321 cggttccagt tatcgccagt acatcctgag tttgtggctg ccgttttatc tctcgctgcc
    10381 gacgctggtg gtcagttatg cgctgggcat tgtgctgaaa gggcaactgg cgctggggat
    10441 gctgctggcg gtgcaaatag ccacgggcgt gctggcgttt gtggtgatga ttgtgctgtc
    10501 gcgccatccg ctggtggtgg aagtgaagcg tcagttttgt cgcagcgaaa aaatgaaaat
    10561 gcttttacgg gcggggtgaa tggttgtttt cggttccggc aacggttgcc ggatgcggcg
    10621 taaaacgcct tatccgtcct ggggggctgg gcttggatct tgtaggtctg ataagacgcg
    10681 ttagcgtagc atcaggcact gaatgccgga tgcggcgtga acgccttatc cggcctacgg
    10741 ttctgtgctc ggatcttgta ggcctgataa gacgcgtcag cgtcgcatca ggcactgaat
    10801 gccggatgcg gcgtaaaacg ccttatccgt cctacggctc tgtgctcggg tcttgtaggc
    10861 ctgataagac gcgtcagcgt cgcatcaggc actgaatgcc ggatgcggcg tgaacgcctt
    10921 atccgtccta cggttctgtg ctcggatctt gtaggcctga taagacgcgt cagcgtcgca
    10981 tcaggcaaaa aacagcaatg aaaacaacaa acacagcctc acctggcatc aaatttatga
    11041 ggaaaaaatg aaattactta ttctgggcaa ccacacttgc ggcaatcgcg gcgacagcgc
    11101 catcctgcgc ggcttacttg atgccatcaa tatcctcaat ccacatgccg aagtggacgt
    11161 gatgagtcgc tatccggtca gttcttcctg gctgctcaac cgcccggtaa tgggcgatcc
    11221 gctgttcctg caaatgaaac aacacaacag tgcagcgggc gttgtcgggc gcgttaaaaa
    11281 agtcctccgt cgccgttacc aacatcaggt actgctctca cgcgtcaccg acactggcaa
    11341 gttgcgtaat atcgccatcg cccagggatt cactgacttc gtgcgcctgc tgtcaggtta
    11401 cgacgccatt attcaggtcg gcggatcgtt ttttgtcgat ctctatggcg tgccgcagtt
    11461 tgaacatgcg ctttgcacgt ttatggcgaa aaagccgctg tttatgattg gtcacagcgt
    11521 cggcccgttc caggataagc aatttaacca actggcgaac tacgtttttg gtcactgcga
    11581 cgcgctgatc ctgcgcgaat cggtcagcct tgatttgatg aaacgcagca atatcactac
    11641 cgcaaaagtt gaacatggcg tcgataccgc gtggctggtc gatcaccaca cagaagactt
    11701 caccgccagc tatgctgttc aacactggct ggacgttgcc gcacaacaga aagcggtggc
    11761 cattaccctg cgtgaactgg caccgttcga caaacgcctc ggcaccactc aacaagcgta
    11821 tgaaaaagcc tttgccgggg tggtcaatcg cattctcgac gaaggctatc aggtgattgc
    11881 gctctccacc tgtacgggca tcgacagcta taacaaagac gaccgcatgg tggcgctcaa
    11941 tctgcgccag cacatcagcg atcctgcccg ttaccacgtg gtgatggatg aactcaacga
    12001 tctggaaatg ggcaaaattc tgggggcctg tgaactcacc gtcggtacgc gcctgcactc
    12061 cgccattatc tcaatgaact ttgccacccc ggcgattgcc atcaactatg aacataaatc
    12121 cgccgggatc atgcagcagc tgggactacc ggagatggcg attgatatcc gtcatttatt
    12181 agacggcagc ctgcaagcga tggttgcgga taccttaggc caacttccgg cgctgaacgc
    12241 acgacttaac gaagccgtca gtcgcgaacg tcagacagga atgcagatgg tgcagtctgt
    12301 gcttgagcgc atcggggagg tgaaatgaag gtcggcttct ttttattgaa atttccgctg
    12361 tcgtcggaaa ccttcgtcct caaccaaatc actgcgttta ttgatatggg ctttgaggtg
    12421 gagattgtcg cgttgcaaaa aggcgacaca caaaacaccc acgcggcatg gacgaaatac
    12481 aaccttgccg ccagaacccg ctggttacag gacgaaccta cgggcaaagt ggcgaagctg
    12541 cgccaccgag ccagccagac cttacgcggc attcatcgta aaaatacctg gcaggcgctc
    12601 aacctcaaac gctatggcgc agagtcgcgg aacctgattt tgtctgccat ttgtggtcag
    12661 gtcgcaacat cgttacatgc cgatgtcttt atcgcacatt ttggccctgc gggggtaacc
    12721 gcagcaaaac tccgcgaact gggtgtcatt cgcggcaaaa ttgccactat cttccacggc
    12781 attgatatct ccagtcggga ggtgctcaac cattacactc ccgaatatca gcaactgttt
    12841 cgccgtggcg acctgatgct accaataagc gatctgtggg ccggaaggct gcaaaaaatg
    12901 ggctgcccga gggaaaaaat cgccgtatcg cgcatgggcg tggacatgac gcgctttagc
    12961 ccgcgtccgg tgaaagcgcc tgcaacgccg ctggaaatca tttccgtcgc acgcttaacc
    13021 gagaaaaaag gcctgcatgt ggcgattgaa gcctgccgtc agttgaaaga gcagggcgtg
    13081 gcatttcgct atcgcatcct cggcattggc ccgtgggaac gacgcctgcg caccctcatc
    13141 gaacaatatc aactggaaga tgtggtggag atgccgggct ttaaaccgag ccatgaagtg
    13201 aaagagatgc tcgatgacgc ggatgtcttc ctgttgccat cggttacggg tgcggatggc
    13261 gatatggaag gtattccggt ggcgctaatg gaagcgatgg cggtcggtat tccggtggtt
    13321 tctactctgc atagcggaat tcctgaactg gtggaggctg acaaatccgg ctggctggtg
    13381 cctgagaacg atgctcgcgc actggcgcaa cgactggcgg cgtttagcca actggacagc
    13441 gacgaactgg ctcctgtcgt caaacgtgct cgcgaaaaag tcgaacacga ttttaaccag
    13501 caggtgatca atcgagaact cgccagcttg ctgcaggctt tatagaggag aacgcatgcc
    13561 atttaaaaaa ctctcccgac gcaccttcct gacggcaagt tctgtgcttg ccttcctcca
    13621 tacgcctttc gcccgcgcac ttcccgctca acaaagcgtt aacattaacg actacaaccc
    13681 tcacgactgg atcgcctcat ttaaacaagc cttcagcgaa gggcaaacgg tcgtcgtgcc
    13741 cgccggattg gtttgtgaca atatcaacac cggcatcttc attcctcctg gcaaaacgtt
    13801 acacatcctt ggaagcctgc gcggcaacgg caaagggcga tttgtcttac aggacggcag
    13861 ccaggtgaca ggggaggggg gcggcagtat gcataacatc accctggatg tgcgcggctc
    13921 tgactgcacc atcaaagggc tggcgatgag cggctttggt ccggtaacgc agatttatat
    13981 cggcggcaaa aacaaacggg tcatgcacaa cctgaccatc gataacctga ccgttagcca
    14041 cgctaattac gccatcttac gccagggatt tcataaccag ataatcggtg ccaacatcac
    14101 caactgtaag ttcagcgact tacagggcga cgctattgaa tggaacgtgg cgattaacga
    14161 cagtgatatt ttgatatccg accatgtcat cgagcgcatc aactgtacta atggcaaaat
    14221 caactggggc attggcatag gccttgcggg aagcacttat gataataatt acccagaaga
    14281 tcaggcagtg aaaaactttg tcgtggcgaa tatcacggga tcggattgtc ggcaactgat
    14341 ccatgttgaa aatggtaaac attttgttat ccgtaatatc aaagctcgta atatcacgcc
    14401 ggatttcagt aagaaagcag gtattgataa cgccacagtt gctatttatg gttgtgacaa
    14461 ctttgtgatt gataatattg aaatgattaa tagtgccggg atgttaatcg gctatggggt
    14521 aattaaaggc aaatatctct cgataccgca gaatttccga gtgaatgata ttcaattgga
    14581 taatactcat cttgcttata aattgcgcgg catccaaatc tccgccggga atgctgtctc
    14641 ctttgtggcg ctgactaaca ttgagatgaa gcgtgcgtcg ctggagttac acaacaaacc
    14701 gcaacatctt tttatgcgta atatcaatgt gatgcaggaa tcctcagttg gaccagcatt
    14761 gagcatgaac tttgacatgc gcaaagacgt tcgaggcgtg tttatggcga aaaaagaaac
    14821 actgctgtct cttgcaaatg ttcatgcggt gaatgaaaaa gggcaaagct ccgtcgatat
    14881 cgacaggatt aatcaccata ttgttaatgt ggaaaagatt aactttagat tgccggaacg
    14941 gagagagtag atttgcgacc attcctggaa aaatggagtc atacttagga acaatgctac
    15001 tgcaatccac aacgaagcgg cgtaacatca caagtaattc agtaatcaat tcagggtaat
    15061 tgatgctggc gaaaaaaatc gaacaagcta taattcagca accattttac aggtggatga
    15121 aataatgacg aatttaaaag cagttattcc tgtagcgggt ctagggatgc atatgttgcc
    15181 tgccactaag gcgattccca aagagatgct accgatcgtc gacaagccaa tgattcagta
    15241 cattgttgac gagattgtgg ctgcagggat caaagaaatc ctcctggtaa ctcatgcgtc
    15301 caagaacgcg gtcgaaaacc acttcgatac atcttatgaa ttagaatctc tccttgaact
    15361 gcgcgtgaag cgtcaactgc tggcggaagt acagtccatc tgtccgccgg gcgtgaccat
    15421 tatgaacgtg cgtcagggcg aacctttagg tttaggccac tccattttgt gtgcgcgacc
    15481 tgccattggt gacaacccat ttgtcgtggt actgccagac gttgtgatcg acaatgccag
    15541 cgccgacccg ctacgttaca accttgctgc catgattgca cgtttcaacg aaacgggccg
    15601 cagccaggtg ctggcaaaac gtatgccggg tgacctctct gaatactccg tcattcagac
    15661 taaagagccg ctggatcgtg aaggtaaagt cagccgcatt gttgaattta tcgaaaaacc
    15721 ggatcagccg cagacgctgg actcagacat catggccgta ggtcgctatg tgctttctgc
    15781 cgatatttgg ccggaactgg aacgtactca gcctggtgca tggggacgta ttcagctgac
    15841 tgatgccatt gctgagttgg caaaaaaaca agcagttgac gcaatgctga tgactgggga
    15901 cagttacgac tgcggaaaga aaatgggtta tatgcaagcg tttgtgaagt atgggctgcg
    15961 taacctgaag gaaggggcga agttccgtaa aggtattgag aagctgttaa gcgagtaaca
    16021 aattcctgac tggaagtgtc ggtcagtaag taattaaaaa cggcagtgaa gattcatagc
    16081 ataagttttg ctcattgaat ctcactgccg ttgtcttttt tataagtaca ataaaaacag
    16141 catgttagct tgcaatcata gttcaaattt ttccaggatt ttccttgttt ctacagctgt
    16201 ttggtaagac aattagcgtt tgaatttttc ggatttggca cgagtgggtt acgctcgtca
    16261 catcgtggaa atgtacgcag tgctctggta gcggttaagc caggggcggt agcgtgcatt
    16321 aatgcatcta ttaatcaaat ctggagcagt ctatttcaca gcatgctctc tggctatatg
    16381 gaataaaaaa gtgaagatac ttgttactgg tggcgcagga tttattggtt ctgctgttgt
    16441 tcgtcacata ataaataata cgcaagatag tgttgttaat gtcgataaat taacatacgc
    16501 cggaaacctg gaatcacttg cagatgtttc tgattctgaa cgctatttct ttgaacatgc
    16561 ggatatttgt gatgcagctg caatggcacg gatttttgct cagcatcagc cggatgcagt
    16621 gatgcacctg gcagctgaaa gccatgttga ccgttcaatt acaggccctg cggcatttat
    16681 tgaaaccaat attgtgggta cttatgtcct tttagaagcg gctcggaatt attggtctgg
    16741 tctggatgat gaaaagaaaa aaaacttccg ttttcatcat atttctactg atgaggtgta
    16801 tggtgactta ccccatccgg atgaagtaaa tagcaatgaa acgttgccgc tatttacgga
    16861 aacgacagca tacgcgccaa gtagtccata ttctgcttct aaagcttcca gcgatcattt
    16921 ggttcgcgca tggaaacgta cttatggttt accgaccatt gtgactaatt gctcgaacaa
    16981 ctatggtcct tatcatttcc cggaaaagct tattccactg gttattctta attcactgga
    17041 aggtaaggca ttacctattt atggcaaagg agatcagatc cgcgactggt tgtatgtaga
    17101 ggatcatgct cgagcgttat ataccgtcgt aaccgaaggt aaagcgggcg aaacttataa
    17161 cattggtgga cacaacgaaa agaaaaacat cgacgtagtg ttcactattt gtgatttgtt
    17221 ggatgagata gtcccgaaag agaaatctta ccgcgagcaa attacttatg ttaccgatcg
    17281 tccgggacac gatcgccgtt atgcgattga tgctgagaag attggtcgcg aattgggatg
    17341 gaaaccacag gaaacgtttg agagtgggat tcgtaaaacg gtggaatggt acctgtccaa
    17401 tacaaaatgg gttgataatg tgaaaagtgg tgcctatcaa tcgtggattg aacagaacta
    17461 tgagggccgc cagtaatgaa tatcctcctt tttggcaaaa cagggcaggt aggttgggaa
    17521 ctacagcgtg ctctggcacc tctgggtaat ttgattgctc ttgatgttca ctccactgat
    17581 tactg
//
LOCUS       DAPOXO010000097        17491 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPOXO010000097 DAPOXO010000000
VERSION     DAPOXO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17491
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.097"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            363..1187
                     /gene="gadX"
                     /locus_tag="ROH59_004132"
     CDS             363..1187
                     /gene="gadX"
                     /locus_tag="ROH59_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HDX4806549.1"
                     /translation="MQPLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIQV
                     DKCVENFVLVSRDTLSLFLPMLKEEALKLHVHKKVPSLLVHHCTRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDTQFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEGTSYSQLLTECRMQRALQLIVIYGVSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQELPNCGSAASMAAQGIFYGTDRSAEGIRL"
     gene            1556..2284
                     /gene="gadW"
                     /locus_tag="ROH59_004133"
     CDS             1556..2284
                     /gene="gadW"
                     /locus_tag="ROH59_004133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HDX4806550.1"
                     /translation="MAHVCSVILVRRSFDIHHEQQKISLHNESILLLDKNLADDFAFC
                     SLDTRRLDIEELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPIQLVTAIFDSFNDPR
                     VNSPILSKMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFSQHSPGTFS"
     gene            complement(2647..5760)
                     /locus_tag="ROH59_004134"
     CDS             complement(2647..5760)
                     /locus_tag="ROH59_004134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HDX4806551.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIK
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKNNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPNQVIGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPVEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(5785..6942)
                     /gene="mdtE"
                     /locus_tag="ROH59_004135"
     CDS             complement(5785..6942)
                     /gene="mdtE"
                     /locus_tag="ROH59_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HDX4806552.1"
                     /translation="MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPG
                     SVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELN
                     SAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
                     EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQD
                     FLRMKEEVASGQIKQVQGSTPVQLNLENGKRYGQTGTLKFSDPTVDETTGSVTLRAIF
                     PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIE
                     ASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            7002..7331
                     /locus_tag="ROH59_004136"
     CDS             7002..7331
                     /locus_tag="ROH59_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806553.1"
                     /translation="MRDLQTSGIVGLSASKMGCKHSDRHGEVNDKKNVAVLPTVSASI
                     RATKGSTGGYTYQGNKVVFVSPSIITGGIEISICIPRHASHQFQLLMSLLKIRCDTQG
                     DDVAHTS"
     gene            complement(7281..7808)
                     /gene="gadE"
                     /locus_tag="ROH59_004137"
     CDS             complement(7281..7808)
                     /gene="gadE"
                     /locus_tag="ROH59_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HDX4806554.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
                     RRMSDIVTLGITSYF"
     gene            complement(8607..9179)
                     /gene="hdeD"
                     /locus_tag="ROH59_004138"
     CDS             complement(8607..9179)
                     /gene="hdeD"
                     /locus_tag="ROH59_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HDX4806555.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKKQ"
     gene            9434..9766
                     /gene="hdeA"
                     /locus_tag="ROH59_004139"
     CDS             9434..9766
                     /gene="hdeA"
                     /locus_tag="ROH59_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HDX4806556.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKKASFKDKVKGE
                     WDKIKKDM"
     gene            9882..10208
                     /gene="hdeB"
                     /locus_tag="ROH59_004140"
     CDS             9882..10208
                     /gene="hdeB"
                     /locus_tag="ROH59_004140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HDX4806557.1"
                     /translation="MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            10272..10919
                     /locus_tag="ROH59_004141"
     CDS             10272..10919
                     /locus_tag="ROH59_004141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDX4806558.1"
                     /translation="MTAEFIIRLILAVIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLGHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(10971..11741)
                     /locus_tag="ROH59_004142"
     CDS             complement(10971..11741)
                     /locus_tag="ROH59_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter ATP-binding protein"
                     /protein_id="HDX4806559.1"
                     /translation="MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLL
                     RQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHP
                     HRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLF
                     LDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCVLHDLNLAARYADRVVLMQKGKVIA
                     NGKPQDVLTQQALTMLYGADITVLKDPANHSPLIVLDH"
     gene            complement(11738..12694)
                     /gene="chuU"
                     /locus_tag="ROH59_004143"
     CDS             complement(11738..12694)
                     /gene="chuU"
                     /locus_tag="ROH59_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease ChuU"
                     /protein_id="HDX4806560.1"
                     /translation="MGLSLLLLALVLFGASQGALKISFDALFDEEYRDIWLNIRLPRV
                     LLAVLVGAALATAGVIMQGLFRNPMADPGLLGVSSGSALMVGVAIVLPFSFPVVLVLY
                     EQMVFAIAGSLVVCTIIFLITQRHRDGSMMQLLLAGIAINALCGAAIGILSYIGDEQQ
                     LRQLTLWMMGNLGQAQWPTLLVASSFILPAIIATTCLAGTLNLLQLGDEEAHYLGVNV
                     KRKRQQLLLVSSLLVGAAVSVSGIIGFIGLVIPHLIRMTTGANHRWLIPCSALAGACL
                     LLMADTLARTLVQPAEMPVGLLTSLLGGPYFMWLILRNRRIT"
     gene            complement(12779..13402)
                     /gene="chuY"
                     /locus_tag="ROH59_004144"
     CDS             complement(12779..13402)
                     /gene="chuY"
                     /locus_tag="ROH59_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobilin reductase"
                     /protein_id="HDX4806561.1"
                     /translation="MTPWLLFGAGGKGVGARTLELALAEQRPVVAVIRHADAATKLAQ
                     QGVQVFTGDACDASVVAAACRAAGPDALIISTMGGAQDYLAHRTVIDEAEKAGISRMI
                     LVTSLGCGDSWPFLSERAKAAFGQAVREKTLAESWLQTSQLDYAILRPGGLLDGAATG
                     KAQRIQNQECHGFVNRADVAAHIHELANAPALNQQVYSLIEPDLKPA"
     gene            complement(13402..13896)
                     /gene="hutX"
                     /locus_tag="ROH59_004145"
     CDS             complement(13402..13896)
                     /gene="hutX"
                     /locus_tag="ROH59_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme utilization cystosolic carrier protein
                     HutX"
                     /protein_id="HDX4806562.1"
                     /translation="MSHVSLQEFLKTEPDGTLEAIAEQYNTTLLEVVKNLPSPTVVSG
                     DKFDTVWDTVCEWGNVTTLVHTTDVILEFSGELPSGFHRHGYFNLRGKHGMSGHIKAE
                     NCTHIALIERKFMGMDTASILFFNKEGSAMLKIFLGRDDHRQLLSEQVSAFHALAASL
                     KEHA"
     gene            complement(13909..15246)
                     /locus_tag="ROH59_004146"
     CDS             complement(13909..15246)
                     /locus_tag="ROH59_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme anaerobic degradation radical SAM
                     methyltransferase ChuW/HutW"
                     /protein_id="HDX4806563.1"
                     /translation="MNTNNTLDLTPHFALDGDQPFKDRRAMMPFRGAIPVAKEQLVQT
                     WQEMINQTVSPRKRLVYLHIPFCATHCTFCGFYQNRFNEDVCAHYTDALIREIELEAD
                     SVLHQSGPIHAVYFGGGTPSALSAHDLARIITTLREKLPLAPDCEITIEGRVLNFDAE
                     RIDACLDAGANRFSIGIQSFNSKIRKKMARTSDGPTAIAFMESLVKRDRAAVVCDLLF
                     GLPGQDAQTWGEDLAIARDIGLDGVDLYALNVLPNTPLGKAVENGRTTVPSPAERRDL
                     YLQGCDFMDDAGWRCISNSHWGRTTRERNLYNLLIKQGADCLAFGSGAGGSINGYSWM
                     NERNLQTWHESVAAGKKPLMMIMRNAERNAQWRHTLQSGIETARVPLDELTPHAEKLA
                     PLLAQWHQKGLSRDASTCLRLTNEGRFWASNILQSLNELIQVLNAPAIALEKP"
     gene            complement(15266..16180)
                     /gene="chuT"
                     /locus_tag="ROH59_004147"
     CDS             complement(15266..16180)
                     /gene="chuT"
                     /locus_tag="ROH59_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312409.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     ChuT"
                     /protein_id="HDX4806564.1"
                     /translation="MPRIITRPFLFSPLTLCISAVVSAAKTMVKRKKLFTALLALSWT
                     FSVTAAERIVVAGGSLTELIYAMGAGKRVVGVDETTSYPPETAKLPHIGYWKQLSSEG
                     ILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVPATLEQMYANIRQLAKTLQVP
                     EQGEALVTQINQRLERVQQNVAAKKAPVKAMFILSAGGSAPQVAGKGSVADAILSLAG
                     AENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRSIAGITHTAAWKNQRII
                     TVDQNLILGMGPRIADVVESLHQQLWPQ"
     gene            16864..>17491
                     /gene="chuA"
                     /locus_tag="ROH59_004148"
                     /gene_synonym="shuA"
     CDS             16864..>17491
                     /gene="chuA"
                     /locus_tag="ROH59_004148"
                     /gene_synonym="shuA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent heme/hemoglobin receptor
                     ChuA/ShuA"
                     /protein_id="HDX4806565.1"
                     /translation="MSRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSF
                     EAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTGRTNGQDVNMRGYDHRGVLVL
                     VDGVRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQ
                     EGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQ"
BASE COUNT         4591 a         4089 c         4177 g         4634 t
ORIGIN      
        1 tcacgttgta aaaaccgaat gcccaacctt taaaaacagg tgggtattcg gctacttatt
       61 aattgcaata atatattacc tgtctattca tcgtgttgat aagatatatg ttatatgaat
      121 gttatggagc atagcgatac tgcttaatat tacgatgatg aattatttgc ttactattaa
      181 ttcctctgcg ttcttaagtc ccctttttat ataataaatc cagtcatcca gcccgagtat
      241 catcgctcat tatcatcctg ttttcccgct tcgtttaaat ttatttatca atcaatttga
      301 cttaagaggg cggcgtgcta cattaataaa cagtaatatg tttatgtaat attaagtcaa
      361 ctatgcaacc actacatggt aattgtctaa ttgcgtacgc aagacataaa tatattctca
      421 ccatggttaa tggtgaatat cgctatttta atggcggtga tctggttttt gcggatgcaa
      481 gccaaattca agtagataag tgtgttgaga atttcgtatt agtttcaaga gacacgcttt
      541 cattatttct cccgatgctc aaggaggagg cattaaaact tcatgtacat aaaaaagttc
      601 cttcattact cgttcatcac tgtaccagag atattcctgt ttttcaggaa gttgcgcaac
      661 tatcgcagaa taagaatctt cgctatgcag aaatgctacg taaaagggca ttaatctttg
      721 cgttgttatc tgtttttctt gaggatacgc agtttatacc gttacttctg aacgtgttgc
      781 aaccgaatat gcgaacacga gtttgtacgg tcatcaataa taatatcgcc catgagtgga
      841 cattagcccg aattgctagc gaattgttga tgagtccaag cctgttaaag aaaaaattgc
      901 gcgaagaagg tacgtcatat tcacagttgc ttactgagtg taggatgcag cgtgctttac
      961 aacttattgt tatatatggg gtttcaatta agcgagttgc agtatcctgt ggatatcaca
     1021 gcgtgtcgta tttcatttac gtttttcgaa attattatgg gatgacgccc acagagtatc
     1081 aggagcgatc ggcgcaggaa ttaccgaact gtggctcggc ggcaagtatg gctgcgcaag
     1141 ggatttttta cggcactgac cgttctgcgg aaggaataag attatagagt tttactcaga
     1201 cataaaaaaa acccggcata ggggaccggg aagaggatag tctgccgtct ccagactaat
     1261 aaaccgttat aacactccct gttggcacgg gaaactttgt gctctcagta agttaaatat
     1321 aacttttact ggaaataaga tcagccattt ttttataaac ataagctata cgctgtgtga
     1381 aaatataatc gtgttgcatt tacttattat caattaactg ttatgcaaaa ctactttgtg
     1441 gataaaattt ggtcctacca aatatggcag tttttgcaca cagaaacagt ctggcgtcat
     1501 ttcattagta tactgacatt gaaataatcg cagtaatgaa atataaggga tagtcatggc
     1561 tcatgtctgc tcggtgatcc tcgttcgtcg ttcattcgat attcatcatg aacagcaaaa
     1621 aatatcgttg cataacgaga gtatcctgct gctggataaa aatttggcag acgattttgc
     1681 gttttgttca ctggatacgc gacggctgga tatcgaagag ctgacagttt gccattactt
     1741 acaaaatatt cgtcagttgc cacgcaattt aggattgcat agcaaagacc gtttgttaat
     1801 taaccagtca ccccccatac agctggtgac ggcgattttt gatagtttca atgacccccg
     1861 ggtcaattcg ccgatactga gcaaaatgct ctatctttcc tgtttatcaa tgttttctca
     1921 taagaaagaa ctgatcccct tacttttcaa tagtatcagt actgtttcag gaaaagttga
     1981 acgccttatt agctttgata tcgctaaacg ttggtatcta cgcgatatcg cagaaagaat
     2041 gtacaccagc gagagtctca tcaaaaaaaa gttgcaggat gaaaatacct gtttcagtaa
     2101 aatattactc gcctccagga tgtcgatggc cagacgatta ctcgagttac gtcaaatacc
     2161 tctgcatact attgcggaaa aatgtggcta tagcagtacg tcatacttta taaatacatt
     2221 tagacaatat tatggtgtaa cgccacatca gttttcgcaa cattcgccgg gtaccttttc
     2281 ctgacatatt tcgcatttga atattggtca ggatctcacg tctgcttcat gtgaaactct
     2341 ttcctgatga tttctgccgg gctaccggct agttctcttt cgcagtttgc caggcggtat
     2401 aggtattttc aggaggaaaa gactcggcat gtttgggatt attaagctaa caattcatac
     2461 gattacggga atgtgggtca gtattgtgct gttcaaattg atgacgaatg gctggagtgg
     2521 tttctacttt cagtgctgtg tactaagcct ggtattcctg acggttagct ggttgttgag
     2581 tggtgaatgg ttagcaggaa agagtaaggc tgaaccctca cgttcaacct tactctcatt
     2641 tacacgttac gcttttttaa agcgggcaaa gagatgttcc actacaacga aaaagaccgg
     2701 aacgaagtaa attgccagca ctgttgcggc aaacatcccg cccattacgc cggtacctac
     2761 cgcgttttgc gcgccagagc cggcaccatg actgataacc agcggcagca cgccgagaat
     2821 aaaggccaga gaagtcatca ggattgggcg taaacgcata cgcgctgctt cgatgattgc
     2881 ctctaccggt gttttccctt ctttctgcat catctcaacg gcaaattcga caatcaggat
     2941 ggcgttcttg gcggaaagcc cgatggtggt cagcaaacca acctggaagt aaacgtcatt
     3001 acttaagccg cgcagatcgg tggccagtaa tgcgccaacg acgcctaacg gaacaaccaa
     3061 catcaccgag aacggaattg accagctttc ataaagtgcg gcgagggcga ggaacaccac
     3121 gaccagtgaa atggcatata gcgcgggagc ctgatttgag gataacgctt cctgatacga
     3181 cagtccggtc catgagtagc cgacgcctgc cggaagtttt gcgaccaggt ctgccataaa
     3241 tttcatggcg tcaccggtac ttttcccggc agccgcttca cctaaaatct ccattgacgg
     3301 gatgccgttg tagcgttcca gtcgcggtga accataggtc cattcggtag acgaataggc
     3361 agaaagcggt gccatcgtgc cagaggcgtt gcgtacatac cattggttga tgttatccgg
     3421 caacatacgg aacggcgtgc ctgcctggac atacactttt ttcacccgcc cctggttgag
     3481 gaagtcgttc acgtagctgc tgccgaaggc ggtggaaatt gtctggttga tatcagacag
     3541 cgccacaccc atagcctcgg ctttcgcagc gttgacgttc actttgaaca tcggcgtatc
     3601 ttccaggccg ttcgggcgta ccccgatgac ctgattcggt gattgcgctg ccagtgataa
     3661 cagctcgttt cgcgcctggg tcagtttttc gtgccccaga ttgccgttgt ccagcagttc
     3721 catatcaaaa cctgacgcgg tacccagttc agccaccgcg ggtaagttga acgggaagac
     3781 gacggcttta ttgatactgc ttagcgcaat cattgcccgc tgaataatcg cggtaaccga
     3841 gttttcctcg ccgacacgtt cagaccacgg cttgaggctg ataaacgcca gaccgttgtt
     3901 ttgcccctga ccactgaagc caaagccacc aacggtaaac accgactgaa cattattttt
     3961 ctcttttgtc agataataat ccgtcacctg ttgtagcact ttcgtggtgt taaccatggt
     4021 tgcaccggaa ggtaactgcg cggtggtcat aaataccccc tgatcctctt ctggtaagaa
     4081 agaggtcggc gtacgcagga acagcaccgc catcccggcg caaatcagta ggtagaccac
     4141 catgtagcga ccggtacaac gcaacagcga gcgggtgctg tcggtatagt gctgagttga
     4201 tttttcaaac agcgtgttga agcgtgcgaa cagggcgtta ggtttgtgac cgccctccgg
     4261 cgcggctttc agaatggtgg cgcacagggc aggggtcagg ctcattgcta caaatactga
     4321 aagcagcatg gaggagatca gcgtgatgga gaactggcgg tagatctccc cggtcgcacc
     4381 gctcataaag gccatcggca taaacactgc ggaaagaaca acggcaatcc cgaccagcgc
     4441 acgttggatc tgccccatcg atttatgcgt cgcttccttc ggcggtagct tatcttccgc
     4501 aatgacacgc tcgacgttct ccaccaccac gatggcgtca tccaccagta accctatcgc
     4561 cagcaccatc ccgaacatag ttaacgtgtt gatggtgaaa ccaactgccg acaagatcgc
     4621 aaacgtcccg agaataacca ccggtacggc aatcgtcggg atgattgtgg cgcggaaatt
     4681 ctgcaaaaac agatacatga ccaggaagac gaggatgata gcctcaacca gcgttttgaa
     4741 aacttcctga atagaaattt tgataaacgg tgtggtgtcg taaggataaa ccgtcttcag
     4801 gcttgcaggg aaataagccg ataaacggtt cagctcctct ttcaccgctc gcgaggtatc
     4861 cagggcgttt gctccggtag ccagtttgat ggcgatcccg gcggcaggtt tgccgttata
     4921 gcgcgccacg gtggaataat cttccgcccc aagttcgacg cgggcgacat cacgcagcag
     4981 cacttgcgaa ccatcttgct gaactttcaa caggattttg ccaaattctt ccggcgtttg
     5041 cagacgcgtc tgcacaatga tcgaggcgtt cagttgctgg tctgccgcct gtggcatgcc
     5101 acccagttga ccaccagaaa tctggttgtt ttgcacctta atctgggaaa taacatcgga
     5161 aggtaccagg ttatatttat tgagtttttg cgggtccagc cagatacgca tggcgtactc
     5221 ggaaccaaag agctgtacgc taccaacgcc cgcggtacgg cttagcgggt ctttgatatt
     5281 agacgctaca tagtccgcga tatcgtactg gttgaggctg ccgttatcag aaataaatgc
     5341 cgctaccatc aggatattac tgctcgactt atcgacgcta atcccctgct gctgcaccgc
     5401 ttcaggtaat gaaggcatag cgagttgcag tttattttgc acctgaacct gtgcgatatc
     5461 aggcgatgtc cccgtctcga aggtcagagt gatggaggca ttacctgccg catcgctggt
     5521 tgaagacatg tacatcaggc catcaagccc attcatattt tgctcaatca cctgagtgac
     5581 cgagtcttct accgtttgcg catcggcacc cggataggtt gcgctgacgg taatggtcgg
     5641 tggcgcaatc tgcggatact gcgcaaccgg taagttcatg atcgccagac cgcctgcaag
     5701 catcataata atggcaagta cccaggcaaa aaccgggcga tcaataaaat agttagccat
     5761 gaaagtcccc ttaagcctgc aacgttattg tttcgattcg gtgctggcgt tttcctggct
     5821 ggaggaaatt gctcgtgctt tgatacccgg acgaatgcgt tgcaagccgg aaacgatcac
     5881 ccgatcgcca gcctgcaagc cagaggtgac aacccactgg tcgccgatgg ctttgctggc
     5941 ttcgatttcg cgtagctgca cgacatcgtc tttatccaga atgagtgccg ttgctttacc
     6001 ctgggcgttg tgggtgacgc cttcctgcgg caccagtaat acattctggc ggctaccttc
     6061 atccactaat gccgtaacat acatgccagg cagcaagtca ccatttgggt tggggaaaat
     6121 cgcccgtaac gtcacggagc ccgtggtttc atccaccgtc gggtcggaga atttcagcgt
     6181 gccggtctgg ccgtaacgtt taccattttc cagattgagc tgtactggcg tactgccctg
     6241 aacctgtttg atttgcccac tggcgacctc ttctttcatg cgcaagaaat cctgcaccga
     6301 ctgcgtgaga tcgacataaa tcgggtccag acgttgtacg gtaaccagcg aatctgcctg
     6361 attagcggta acgagtgcgc cgacggtcac cgacgatttc ccgctgacgc ccgtaatcgg
     6421 cgaggtgaca ttcgcgtatt gcagattgat cgtcgcctgt tcaacagccg ctttggcgac
     6481 ggtgacattg gcttctgctt cattcaactg ggtgcgcgcg gtgtcgtaat cctgacggct
     6541 aacatagttg gtcttcagca acgatgcctg gcggttaaag gtgatgcggg cattgctggc
     6601 ggtagagagc gctttcgcca gcgagccttt ggcggagttc agctctgcct gtaaaggcgc
     6661 aggatcaatc tgatacagcg aatcgccctg gttcacttta tcgccttcga taaagttgcg
     6721 tttaatgata attccgccca cctggggacg tatctcggca acttcataag gaacggttct
     6781 accgggcaat tcgctcaaca cattgaccga accgggggag agtgtgacga caccgacctc
     6841 aggcgtcatg gcggcggcgt tttccgccga tttgtcatcg caggcggtga gcatcgcgcc
     6901 gcagaataac aacggtatta acagttttct tcttctgttc attttagtcc ctgaaaattc
     6961 ttgagaaata acggttcttt aaattgcgcg cgaggagaga tatgagggat ttacagacca
     7021 gcggcatagt ggggttgtca gccagtaaga tgggatgcaa gcacagtgat cgacatggtg
     7081 aggtcaacga caaaaaaaat gttgccgttc tgccaacagt ttctgccagc attcgggcaa
     7141 cgaagggttc tactggtgga tacacatacc aggggaataa agtcgttttc gtctctcctt
     7201 caataatcac cgggggtatt gaaatcagca tctgcatccc tcgtcatgcc agccatcaat
     7261 ttcagttgct tatgtcctta ctaaaaataa gatgtgatac ccagggtgac gatgtcgctc
     7321 atacgtctta atttcagctt gtacataatg ttgaatttct gaatctttaa tgtttgttgc
     7381 gaaatgttga gcgttgacgt gatattgctt tcatttttgt ttttcagaat cagttgcata
     7441 attttgaact gattatgtga aaaacatagt tgtgaattct tatggggcaa gtgtttacca
     7501 taagtaatct caagaagatt tttgatactt tctttacggc tgacaaaata aataggcgct
     7561 ttagctttta gtttactgat gtgataaggt gccaaaacaa taattctctc ggcatctaat
     7621 ttctccagga atttaatcgc ttcttcatca aggatatggt tgtgataggt gtcaatgatc
     7681 accttgaagg gtttattgcc tacttttttg atctctgaca gggaattgat ttttatcatt
     7741 tcgtgattat ctttcaactg ccaaaagccc tgtaaaagaa aagaatcttt cgtcatgaga
     7801 aaaatcataa cttgctcctt agccgttatc gtttcgaaca tgtcatcctt ttcattattt
     7861 acatccttgt ccgaatcgtt gttcaatata gtaaacgcct ataagaactt tgcccttcgt
     7921 gaactaatac gtctattaac actaatcaat acttcagatt tatccatcac gcactccata
     7981 tattggtcct aagtaagatt cctggttgtt atcagtttgt aactagtaaa caaaaggtta
     8041 acttttgcgg attactgccc aagaataagt tatcaataac cagtttgtga tctctgaaga
     8101 atattactaa agttaaaatg taatccgatt taaatatcga gtctccttgt ttcgacttag
     8161 gctggcaatt ggattgccag ctttctttta acgcattgaa attacctgat taaataactc
     8221 attcatgtct tcaggttttt atatagcgtc tggagacacg gatatttatg caatgtaatc
     8281 aacgccagtt gcaaaaaaat gaacccggat tacttattta accgcccata gcatcaacgc
     8341 ttacggaact ctttgttcac tttcccacag cacttttaaa acattaaacc tgaccacgga
     8401 aaatatcagc catgataatg tttgaaatgg ctaatttgcc atggaacgaa aaaaatcaga
     8461 ttaaattcag taggttgaaa taatcaacag caggcaattg tttcaatgat agtgcgtaat
     8521 tgaactgaaa cactgtatag ctaagagagt attaactgga tcatagtcac ttaatgtgac
     8581 tatgatccag gtggaaatag ggataattat tgctttttaa cgaacaaact ggcgaagctg
     8641 aacagactgg cggcgctaaa tatcagttca attcccacca gtgtggaaac cagcgttacc
     8701 gacaccatcg gcgtagcacc aaggaatatc caggcaatga cgatatccag cacaccaata
     8761 acgagctgta gccaactgcc tttcattgaa cgctgacgat accaactcat caggcgaata
     8821 acccctgcca cacagaacaa accggcaata aatgccgcaa tggcaaaaat gcccagctct
     8881 ggtgcgcgga tgaagaaata gccgatcaat aaataggcga ctgcgacgag gaaaccggat
     8941 aataccggcc agaaattatg actgcggttg ctgaatagcc cgacaataag cgcaatgccc
     9001 gagcagatta ataatgcacc cactactgtg cttaaaatgt cgccagagac gaacggaaaa
     9061 ctgatacaca gcaacccgac gataaacagc agcacggcaa taaactggat tgctctgcga
     9121 tgttttttaa gcatctccag atcaaacttc aaaattgttg ccttatctat atataacata
     9181 gaaccaccct ataaaattaa gaagaaaatc ccctgctatc aatctatgcc aaaaacgcgt
     9241 ctaagaatgc agtcgattta ataaaaattt cctaattaca gtatctgatg catctgtaac
     9301 tcattgtatt gaaataaaaa tatctgattt tgatattttc catcaacatg acatatacag
     9361 aaaaccaggt tataacctca gtgtcgaaat tgattcgtga cggctctttc actttatagt
     9421 tgaggatatt acgatgaaaa aagtattagg cgttattctt ggtggtctgc ttcttctgcc
     9481 agtagtgagc aatgcagcgg atgcacaaaa agcagctgat aacaaaaaac cggtcaactc
     9541 ctggacctgt gaagatttcc tggctgtgga cgaatccttc cagccaactg cagttggttt
     9601 tgctgaagca ctgaacaaca aagataaacc agaagatgcg gttttagatg ttcagggtat
     9661 tgcaaccgta accccagcta tcgttcaggc ttgtactcag gataaaaaag ccagctttaa
     9721 agataaagtt aaaggcgaat gggacaaaat taagaaagat atgtaattcc gggaatgcgt
     9781 tacatcgtat ttccttgcat attgaacagg ccggaatatc ttctttaaaa gcagctattc
     9841 ctcctgtttg tatataatct ctatattgaa tgggttacaa aatgaacatt tcatctctcc
     9901 gtaaagcgtt tatttttatg ggcgctgtag cggctttgtc actggtgaac gcacaatctg
     9961 cgctggcagc caatgaatcc gctaaagata tgacctgcca ggaatttatt gatctgaatc
    10021 caaaagcaat gacaccagtt gcgtggtgga tgctgcatga agaaacagta tataaaggtg
    10081 gcgataccgt tactttaaat gaaaccgatc tcactcaaat tcctaaagtg atcgaatact
    10141 gcaagaaaaa cccgcagaaa aatttgtata ccttcaaaaa tcaagcatct aatgacttgc
    10201 cgaattaatg aggtacaagt aaaaaggagt agcaagttga gccatcttgc tgctcctttt
    10261 tgcattttta tatgacagca gaatttatta tacgacttat acttgcggta attgcctgtg
    10321 gcgctattgg catggaaaga caaatgcgcg gcaaaggagc agggttacgc acacatgtat
    10381 taattggcat gggaagcgcc ctgtttatga ttgtttcgaa atatggtttt gctgacgtgc
    10441 tgtctttagg tcacgtcgga ctagacccca gccgtattgc tgctcaggtt gtgacgggcg
    10501 tcgggtttat cggtgcaggt aacattctcg ttcgtaacca aaatattgta ggtctgacga
    10561 cggcagcgga tatctgggtg accgccgcca ttggtatggt tattggcagc ggtatgtacg
    10621 aactgggtat ttatggttca gtgatgacct tgctggtgct ggaagtcttc catcaattaa
    10681 ccttccgcct gatgaacaaa aattaccatt tacagctgac attagtgaac ggtaatacgg
    10741 tatcaatgct cgactggttt aagcagcaaa aaataaaaac ggatttagtt tcgttgcagg
    10801 aaaatgaaga tcatgaagtg gtcgccattg atatccagct tcatgccacg acgtcgatag
    10861 aagatctgtt gcgattatta aaaggtatgg caggggtgaa aggcgtttca attagctaat
    10921 ctgtatagtt atttattcgc aggagtacca gtgcggtact cctgttggtt ttaatgatcg
    10981 aggacgatca gtggtgaatg gttggcagga tctttaagta cggtaatatc cgcgccgtag
    11041 agcattgtca gcgcctgctg tgtcaatacg tcctgcggct taccatttgc gataaccttt
    11101 cctttttgca ttaatacaac acggtctgca taacgcgcgg caagatttag atcgtgcaat
    11161 acgcagcaaa cattgaactg ccgttcgtga actaactggc gtaataaacg aaacaagtgc
    11221 tgctgatggt gaatatccag cgccgaagtt ggttcatcaa gaaataacca tttcggtgag
    11281 ggagtaggtt cccagagttg caccagcagg cgcgctaatt gcacgcgctg ttgttcacca
    11341 ccggataatt gccgatagtc gcggtttgct aacgcctgac agtcacataa cgccattatt
    11401 tgtgctgttt cattatcctg attaccagta cgatgcggat gccgccccat ctggataact
    11461 tcttgtacgc tgaatggaaa cgccatgtgg ctattttgac gcatcacggc ccggtgtttc
    11521 gccagttcag taatcgacca ttcatttaat ggcttattaa acaaccgaca ttcgccgcta
    11581 tcaggttgaa gatagccggt tagctggcga agcagcgtag attttcccgc accattaggg
    11641 ccgaggatgg caacaatttc cccaccggga aaagtcagcg agacattatc agtcagacgc
    11701 cgcccctgaa ggctataaac cagattctgg gcgctgatca tgtgatcctc cggttgcgca
    11761 gaatcaacca cataaaataa gggccaccaa gcaggctggt taataatccc acgggcattt
    11821 ctgctggctg taccagcgtg cgggcaagcg tgtctgccat cagcaataaa caggctccgg
    11881 cgagggcgga acaagggatt agccagcggt gatttgcccc ggtagtcatg cgaatcagat
    11941 gcgggatcac caggccaata aagccgataa taccgcttac cgatacggca gcaccaacga
    12001 gcagtgagct cactaacagt aattgctggc gtttacgctt aacgttcacg ccgaggtagt
    12061 gggcttcttc atcaccgagc tgcagtaaat tcagcgttcc ggcgagacaa gttgttgcga
    12121 taatggccgg taggatgaat gaactggcaa ccaataacgt cggccattgc gcctgtccaa
    12181 gattgcccat catccacaat gtgagttgtc gtagctgctg ctcatcgccg atatagctca
    12241 ggatgccgat cgctgcgccg cacagggcat tgatggcgat accggcgagt aataattgca
    12301 tcatgctgcc atcgcgatgg cgctgcgtga tgagaaaaat gatggtgcag accactaaac
    12361 ttccggcaat ggcaaacacc atttgctcat agagcaccag caccactggg aaggagaagg
    12421 gcagcacaat agcaacgcca accattaatg cagaaccgct actgacgcca agtaatccag
    12481 ggtcagccat tgggttgcga aaaagccctt gcataattac ccctgcggtt gccaacgctg
    12541 cacctaccag caccgccagc aaaacccgtg gtagacgaat attgagccag atatcgcggt
    12601 attcctcatc aaaaagggca tcaaaactga tctttaacgc tccctgactg gcaccaaaca
    12661 gcaccagagc tagcaataat agtgatagcc ccataaagac cctggcggaa gagagtgaat
    12721 ccttgagcac gcaaaactcc gttacgacat tacggcgcgg acatgccgcg ccgggggatc
    12781 acgccggttt caggtccggt tcaatcagac tgtagacctg ctggttaagt gctggcgcat
    12841 ttgccagttc atggatatgt gcggcgacat cagcacggtt aacaaaacca tgacactcct
    12901 gattttgtat ccgttgtgct ttgcccgttg ccgcaccatc aagcagaccg ccagggcgga
    12961 gaatggcata atcaagctgg ctggtttgca accagctttc cgccagcgtt ttttcccgta
    13021 ccgcctgacc aaacgcagcc tttgcccgct ctgataaaaa cggccagcta tcgccgcatc
    13081 ccaaagaggt caccagaatc atgcgactga tgccagcctt ctcggcctca tcaatcactg
    13141 ttctgtgcgc cagataatcc tgagctccgc ccattgttga gatgataagc gcatccgggc
    13201 cagctgcgcg gcaagcagcc gcgactacgc tggcatcaca ggcgtcgcct gtaaaaacct
    13261 gtacgccttg ttgcgccagt ttcgtggcgg catcggcatg acgaatgaca gcaacgaccg
    13321 gacgttgttc cgccagcgcc agttcaagcg ttctggcacc cacacctttt ccgcccgcac
    13381 caaagagtag ccacggtgtc atcaggcgtg ttcctttaac gatgctgcca gagcatggaa
    13441 ggcgctgact tgttcgctca ggagctgacg atgatcatcc ctaccgagga agattttcag
    13501 cattgcgctg ccttccttat tgaaaaagag aatagaggcg gtgtccatgc ccataaattt
    13561 acgttcgatc aaggcaatat gcgtgcagtt ttctgctttg atatgcccgg acatgccgtg
    13621 ctttccgcgt aggttgaaat agccgtggcg atggaaaccc gaaggcagtt cgccgctaaa
    13681 ttcgagtatt acatcggtag tatgtactaa cgtggtgacg ttgccccatt cgcagacggt
    13741 atcccagaca gtatcgaatt tatcacctga cacaacagtc ggagagggca gatttttcac
    13801 tacctccagc agcgtggtgt tgtattgttc ggcgatcgcc tccagcgtac cgtctggctc
    13861 cgttttcaaa aattcctgta acgagacatg gctcataaat cactcctgtt atggtttttc
    13921 aagcgcaatt gctggcgcat taagtacctg aatcagttca ttaagagact gcaaaatgtt
    13981 gcttgcccag aaacgacctt cattggtcaa ccgcagacac gttgacgcat cgcggcttaa
    14041 gcctttttgg tgccactggg ccagtaacgg cgcgagtttt tcggcatgtg gcgtaagttc
    14101 gtccagcggt acacgcgccg tttcaatgcc cgactgcaag gtatgacgcc actgcgcgtt
    14161 acgttcggcg ttacgcatga tcatcatcag cggttttttg cctgctgcga cggattcatg
    14221 ccaggtctga agattgcgtt cgttcatcca ggagtaacca ttaatcgaac cgccggctcc
    14281 ggaaccaaag gccagacaat cggcaccttg tttaatcagc aggttataga gattgcgttc
    14341 gcgtgtggta cggccccagt ggctgttact gatgcagcgc caaccggcat cgtccataaa
    14401 atcacaccct tgcaggtaaa gatcgcgacg ttctgccgga gagggcacgg tagtacgccc
    14461 attttccacg gctttgccca gcggtgtatt gggcaggaca ttgagcgcat agagatcgac
    14521 gccgtcgaga ccgatatcgc gggcaatagc cagatcttct ccccaggttt gcgcatcctg
    14581 acccggcaga ccaaacagca ggtcacagac caccgcggca cggtcgcgtt tgaccaggct
    14641 ttccataaac gcaatagcgg ttgggccatc cgaggtgcgg gccattttct tgcggatttt
    14701 gctgttaaac gactgaatac caattgagaa gcggtttgct ccagcatcaa ggcaagcatc
    14761 gattcgctca gcgtcaaaat tcagtacccg gccttcgata gtgatttcac aatcaggggc
    14821 cagtggcaac ttttctcgta atgtggtgat gattctggcc aaatcgtgtg ctgaaagcgc
    14881 ggaaggcgta ccgccaccga aatagaccgc gtggatgggg cccgactgat gcaatacgct
    14941 gtctgcttcc agttctattt cacgaatcag ggcgtcggta taatgagcac acacatcttc
    15001 attaaaacgg ttctgataaa aaccacaaaa tgtgcagtgt gtcgcacaaa aaggaatgtg
    15061 taggtaaacc agtcgcttac gtggtgatac cgtttgattg atcatctctt gccaggtctg
    15121 taccagttgc tctttggcaa ccggaatggc cccacgaaac ggcatcatgg cgcgcctgtc
    15181 tttaaagggc tgatcaccgt ctaaagcaaa atgtggcgtg agatccaggg tgttatttgt
    15241 gttcattcgt ctgatttaaa tccatttatt gcggccaaag ctgctggtgt aaagactcaa
    15301 cgacatcagc aatacgcgga cccattccca gaatcaggtt ttgatcaacg gtgataatgc
    15361 gctggttttt ccatgcggca gtgtgggtaa ttccggcaat agaacgtagc cgattaatat
    15421 cgccatcgac catttgtgag gtgacgacaa tcacttcagg gttagccgca atcagcgatt
    15481 ccgcgctgta gcttttgtac tgctggtggg tagcgacgtt ttctgctccg gcaagcgaaa
    15541 gaatggcgtc cgcgacgctg cctttaccgg caacctgtgg cgcacttccg cctgcggaga
    15601 gaataaacat ggctttaacc ggggcttttt tggccgccac gttttgctgt actcgctcca
    15661 ggcgttggtt gatctgtgtc accagcgcct cgccttgttc aggaacctgt aacgtttttg
    15721 ccagttggcg aatgttggcg tacatctgct caagggtggc tggtacacgc ggcagagtga
    15781 cgacgttgac tttttgcgcc cgcagttggt cgagcacaat ttgcggtcct gcatcctgcc
    15841 aggtaattac gctatccggg cgaagtgaca aaatgccttc gctgctgagt tgtttccagt
    15901 aaccaatatg cggcagtttg gcggtttctg gtggatagga tgtcgtttca tcgacaccaa
    15961 ccacgcgttt gccagcgccc atcgcgtaga ttagctccgt cagcgatcct cctgcgacca
    16021 cgatacgttc ggcagccgtt acgctaaaag tccagctaag agccagtaat gccgtaaaca
    16081 atttttttcg ttttaccatg gtcttcgcgg cagagaccac ggctgaaata cataacgtta
    16141 gtggggaaaa aagaaacggc ctggtgatga tccttggcat aatgtgagaa ctcttatcaa
    16201 attgagaatg atcatgatta tcatttgagt tatatatgaa atacaaccgt cgattcaata
    16261 cgcacggcgt tacaagcgta tttatttttg atttttatca agatgcttcg tcagctaatg
    16321 ttcttgttac cgattaaatt tcagcgcggg aaaaagctga gaacccggag atatcgcggc
    16381 ttgcagagca aagagaagag aaaattatca ctgttaacga caacgttttg tgatgaggtt
    16441 gtggggggat agccataaac acaggatggt tttctggatg ctggatagat ttcataaccc
    16501 cctgtttatt gtgttaatgg cggttaaaaa aagcttgatc ataaaaaatt gatcgataat
    16561 aattctcatt atcacgtttg agtttaacaa aatatgacat catggataac aaaatcatat
    16621 cttttgtaag ggaaaacgca cagcactctt cacttcagac gtggcgtact actttgcctg
    16681 acaaagaggg cgtgcttttg ctgaattatc agaaatattc ggcaatttta cgggatatat
    16741 acgctaatag cttcccgtgg tgatatctaa tcatttgaat tgtaaataaa tttatttttc
    16801 gccagccacc ccggtattaa cccaggcagc cagcattttt tattttcctc atggagaatc
    16861 gctatgtcac gtccgcaatt tacttcgttg cgtttgagtt tgttggcttt ggctgtttct
    16921 gccaccttgc caacgtttgc ttttgctact gaaaccatga ccgttacggc aacggggaat
    16981 gcacgtagtt ccttcgaagc gcctatgatg gtcagcgtta tcgacacttc cgctcctgaa
    17041 aatcaaactg ctacttcagc cactgatttg ctgcgtcatg ttcctggaat tactcttgat
    17101 ggtaccggac gaaccaacgg tcaggatgta aatatgcgtg gctatgatca tcgcggcgtg
    17161 ctggttcttg tcgatggtgt tcgccaggga acggataccg gacacctgaa tggcactttt
    17221 ctcgatccgg cgctgatcaa gcgtgttgag attgttcgcg gaccttcagc attactgtat
    17281 ggcagtggcg cgctgggtgg agtgatctcc tacgatacgg tcgatgcaaa agatttattg
    17341 caggaaggac aaagcagtgg ttttcgtgtc tttggtactg gcggcacggg ggaccatagc
    17401 ctgggattag gcgcgagcgc gtttgggcga actgaaaatc tggatggtat tgtggcctgg
    17461 tccagtcgcg atcggggtga tttacgccag a
//
LOCUS       DAPOXO010000098        17431 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.098, whole genome shotgun sequence.
ACCESSION   DAPOXO010000098 DAPOXO010000000
VERSION     DAPOXO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17431
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.098"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(28..759)
                     /gene="rlmB"
                     /locus_tag="ROH59_004149"
     CDS             complement(28..759)
                     /gene="rlmB"
                     /locus_tag="ROH59_004149"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDX4806566.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(850..3291)
                     /gene="rnr"
                     /locus_tag="ROH59_004150"
     CDS             complement(850..3291)
                     /gene="rnr"
                     /locus_tag="ROH59_004150"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313182.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDX4806567.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVSDWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKPKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(3330..3755)
                     /gene="nsrR"
                     /locus_tag="ROH59_004151"
     CDS             complement(3330..3755)
                     /gene="nsrR"
                     /locus_tag="ROH59_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HDX4806568.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(3960..5258)
                     /gene="purA"
                     /locus_tag="ROH59_004152"
     CDS             complement(3960..5258)
                     /gene="purA"
                     /locus_tag="ROH59_004152"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDX4806569.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGLEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(5362..5559)
                     /locus_tag="ROH59_004153"
     CDS             complement(5362..5559)
                     /locus_tag="ROH59_004153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HDX4806570.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(5641..6645)
                     /gene="hflC"
                     /locus_tag="ROH59_004154"
     CDS             complement(5641..6645)
                     /gene="hflC"
                     /locus_tag="ROH59_004154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HDX4806571.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(6648..7907)
                     /gene="hflK"
                     /locus_tag="ROH59_004155"
     CDS             complement(6648..7907)
                     /gene="hflK"
                     /locus_tag="ROH59_004155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HDX4806572.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTDPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(7993..9273)
                     /gene="hflX"
                     /locus_tag="ROH59_004156"
     CDS             complement(7993..9273)
                     /gene="hflX"
                     /locus_tag="ROH59_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDX4806573.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLDDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(9349..9657)
                     /gene="hfq"
                     /locus_tag="ROH59_004157"
     CDS             complement(9349..9657)
                     /gene="hfq"
                     /locus_tag="ROH59_004157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDX4806574.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(9743..10693)
                     /gene="miaA"
                     /locus_tag="ROH59_004158"
     CDS             complement(9743..10693)
                     /gene="miaA"
                     /locus_tag="ROH59_004158"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDX4806575.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLNIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(10686..12533)
                     /gene="mutL"
                     /locus_tag="ROH59_004159"
     CDS             complement(10686..12533)
                     /gene="mutL"
                     /locus_tag="ROH59_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710035.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDX4806576.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRNMDVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAVREPVAPRYTPAPSSGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLSLPVAERWLRQAQLTPGEVPVCAQPLLIPLRLKVSGEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(12543..13874)
                     /gene="amiB"
                     /locus_tag="ROH59_004160"
     CDS             complement(12543..13874)
                     /gene="amiB"
                     /locus_tag="ROH59_004160"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HDX4806577.1"
                     /translation="MMYRIRNWLVATLLLLCAQAGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADAPPSPPPMVAKRVETPAVVAPRVSEPARNPFK
                     TESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNVTI
                     AIARKLRTLLNNDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRSA
                     TGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQADPYLSQAVLDLQFGH
                     SQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEERL
                     LASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(13893..14354)
                     /gene="tsaE"
                     /locus_tag="ROH59_004161"
     CDS             complement(13893..14354)
                     /gene="tsaE"
                     /locus_tag="ROH59_004161"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDX4806578.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(14326..15873)
                     /gene="nnr"
                     /locus_tag="ROH59_004162"
     CDS             complement(14326..15873)
                     /gene="nnr"
                     /locus_tag="ROH59_004162"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDX4806579.1"
                     /translation="MTDHTMKKNPVSIPHTVWYADDIRRGEREAADALGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAIGIDVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLQQAPRESISQLIDHANSH
                     PAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLR
                     LDRWLAGQETKIQRFSAEQLSQWLIPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMGSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLHCAQRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKMSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            15872..17011
                     /gene="queG"
                     /locus_tag="ROH59_004163"
     CDS             15872..17011
                     /gene="queG"
                     /locus_tag="ROH59_004163"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDX4806580.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSESEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGEIPEELRPLMGNRIYGCDDCQLICPWNRYSQLTTEDDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILTALESRKGEH
                     PLLDEHIAWAIAQQIERRNACVVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(16994..17047)
                     /locus_tag="ROH59_004164"
     CDS             complement(16994..17047)
                     /locus_tag="ROH59_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806581.1"
                     /translation="MRFYFYSQAVDESGVTR"
     gene            complement(17281..17356)
                     /locus_tag="ROH59_004165"
     tRNA            complement(17281..17356)
                     /locus_tag="ROH59_004165"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17321..17323),aa:Gly,seq:gcc)
BASE COUNT         3956 a         4962 c         4369 g         4144 t
ORIGIN      
        1 tggatggctt ttcataattc agaggaacta gctgcgctga cgaaccgctt caaataagca
       61 aattccggtt gcaaccgaaa cgttcaggga agaaacactt cctgccattg ggatgctgat
      121 caactcatcg caatgttcac gggtcaggcg acgcatacct tcaccttccg cgcccatcac
      181 cagcgccagg cgtccggtca ttttgctctg atagagtgta tgatccgcct cgcctgccgt
      241 accgacgatc cagatattct cttcctgcaa catacgcatg gtgcgcgcca gattagtcac
      301 ccgaatcagc ggaacgcttt ctgccgcacc acaggccact tttttcgccg tggcgttgag
      361 ctgtgcggag cgatctttcg gcacaatcac cgcatgaaca ccagcggcgt ccgcgctacg
      421 caggcacgcg ccgaggttgt gcggatcggt tacgccgtcg aggatcagca ggaacggttg
      481 atcgagcgaa gcgatcagat ccggcagatc gttttcctga tactgccgtc ctggcttcac
      541 acgagcgata atgccctgat gcacggcacc gtcgcttttc tcgtcgagat attggcggtt
      601 tgccaactgg ataaccacgc cctgagactc aagggcgtga atcagcggta acagacgttt
      661 atcttcacgg ccttttaaaa taaagacttc ctgaaaacgt tcaggggcgc gctccagcag
      721 ggcctgcact gcatggatgc cgtaaatcat ttcgctcatt aatgtactcg ttgtttacgt
      781 tttgccggga gcgccacgct tgcccggcct acggataatt caccctcttc tgtttgaaga
      841 gggtaatgat cactctgcca cttttttctt cgccgcacgc ttcgctttgg tcgctgcggc
      901 tattttctgc gttttcgccg atggcttttt cgcttttctc gcgtctttct tcgctgcttt
      961 cggcttcggt tttttctcgc cacggaaggc gctgtctggc tcaaagttga cctttttgcc
     1021 gacctgacgc cgcttgccgc cttttttgcc tgcatcgcct tttttcgctt tctcgcgcgc
     1081 cgttttaccg acgttgcgcg gtgcgcgttc gctggagatc aggctaaagt cgattttgcg
     1141 ctcgtccata ttaaccgctt cgacgcgaac ttccacgcga tcgcccaggc gataagtctg
     1201 accgctggat tcacccatca ggcgttgccc tacctggtca aagcgatagt agtcattgtc
     1261 cagcgaagag acatggacca gaccatcaat gaacaagtcg tccagacgga cgaagaagcc
     1321 aaagccagtg acgctggaaa ttacgccttt aaagacgtta cctacctggt cgagcatgaa
     1381 gtcacacttc agccagtcag acacatcgcg cgttgcttca tcggcacgac gttccgccat
     1441 cgaacagtgc tgacccagtt gcagcatctc ttccatcgaa taatggtagc cgccggtttc
     1501 agtggtgttg ccctgatgcc cctgctcttt cgccagcaga tatttaatgg cgcggtgcaa
     1561 cgtcaggtca ggataacgac gaatcggcga agtaaagtgc gcataggact gcaatgccag
     1621 accgaagtga ccacggtttt ccggatcgta aatcgcctgt ttcatcgagc gcaaaagcat
     1681 ggtttgcagc atttctgcat caggacgatc ggcaaccgat tccagtaact ctgcatagtc
     1741 gcgcggttcc ggcttgttac cgcccggcaa ttccagcccc agctccgcca gcactgaacg
     1801 gaaagaggta atcgcttcgg tgctcggctt gtcgtgaata cggaacagtg ccggttcttt
     1861 ggctttctca acgaaacgcg ccgccgagat attcgccaga atcatgcact cttcaattaa
     1921 cttgtgggcg tcgttacgct gagtctgttc gatacgttca atacggcgtt cagcgttgaa
     1981 aatgaacttc gcttcttcgc tctcaaatga gatcccaccg cgttcttcac gggctttatc
     2041 cagcacttta tagaggttat gtaactcttc gagatgctta accagcggcg catactgctc
     2101 gcgcagatcc tgatcgcctt gcagtatatg ccagactttg gtgtaggtca gacgcgcgtg
     2161 agaactcatc accgcttcgt agaatttgta gccagtcagg cggcctttcg acgaaaccgt
     2221 catctcgcac accatacaca ggcggtctac ctgcgggttg agcgagcaca ggccgttaga
     2281 gagcacttcc ggcagcatcg ggataacctg cgaagggaag tacaccgacg taccacggtt
     2341 acgcgcttct ctgtccagcg gtgttggcgg acggacatag taactgacgt cggcaattgc
     2401 gacccacaaa cgccagccac cgccgcgttt tttctcacag taaactgcat cgtcaaagtc
     2461 acgggcgtct tcgccatcaa tggtgaccag cggtaaatcg cgcagatcga cacggcccgc
     2521 ttttgcttct tccggcactt cttctttcag cccggcaacc tgttgctcaa cagcctgcgg
     2581 ccagatgtac ggaatttcat gggtacgcag agcaatatca accgccatgc cggtgcccat
     2641 attatcgccc agcacttcga cgattttacc caccgctttg gtacggcgag tcgggcgttg
     2701 agtcagttca accaccacca caaagcccat ccgcgcgccc atgatctgat cgggcgggat
     2761 taagatatcg aagctcagac ggctatcgtc aggaaccaca aagccgacgc ccgcttcggt
     2821 gaagtagcga ccaacaatct ggctggtttt tggcaccagt acgcggacaa tacgcgcttc
     2881 acgacgacct ttacggtcag cgcccagcgg ctgagccagc acctgatcgc catgaatgca
     2941 ggttttcatc tgctcgctgg agagatacaa atcatcttta cgcccttcaa ctcgcagaaa
     3001 gccgtagcca tcacggtggc caataacggt acctttcacc aggtcgaggc gttccggcag
     3061 cgcatagcac tgacggcgag tgaagaccag ttgaccatcg cgctccatcg cgcgcaggcg
     3121 tcgacgcagg ccttcaagct gctcttcgcc ttcaatgtgc agttctaccg ccagctcatc
     3181 acggctggcc ggtttttcac gtttggttaa atgttcgagg ataaattccc gactagggat
     3241 gggattcgcg tatttttcag cttcgcgttc ctggaaagga tcttgtgaca tctcggttcc
     3301 tccgttgtca tctctgatga agattttcgt cactccacca gcaataattt ataaagcggt
     3361 tgattctctt caaccaaatc ggcaagcgtg tagttatcca gttccgtcag aaaactttgc
     3421 acggccttag aaagcgcctg tttcaaccga caggcaggtg taatgtggca aaactcactg
     3481 ctgcaattca ccagcgataa gggctccagc tcgcgcacca catcaccaat acgtatcgca
     3541 ctcgccggtt tacccaagcg aatgccgcca ttttttccac gaacagcagt cacgtagccg
     3601 gcacgactaa gttgattgat tattttgacc atatgattac gggagacgcc gtagacgtca
     3661 gtcacttcag aaatactggt catccgccct tctggcaatg acgccatgta gatcagcgca
     3721 cgtaatccgt aatcagtgaa actcgttaac tgcacatcaa cctcaaaagg gaaatcgggg
     3781 aaaaatacat ttatattgat gataaaccag ccacaagctg tgtcgctaat ttatttcagt
     3841 tcggggaagg aaaaaaacga ggatttaaca ctgtgtcgga tagcgtaatg gcttaaccga
     3901 cacagcaatg tatcacactg ttagcccggc aggcaaaata tctgccatgc gtaccagaat
     3961 tacgcgtcga acgggtcgcg cagaatcatg gtttcagtac gatccggacc ggtagagatg
     4021 atatcgatcg gcacaccggt cagctcttca atgcgcttga tgtagttcag tgccgcctgc
     4081 ggcaggccac tacgatcttt cacgccgaag gtggattcag accagcccgg catggtttcg
     4141 taaatcggct ctagaccttt ccagtcgtca gctgccagcg gagtggtagt cacttcacga
     4201 ccatccggca tacggtaagc cacgcagagt ttaacctctt tcaggccatc cagaacgtcc
     4261 agtttagtca ggcagaagcc agacagggag ttcaactgta ccgcacgacg aacggcaacg
     4321 gtgtccagcc agccggtacg acgacgacga cccgtagttg cgccgaattc gttaccctgc
     4381 ttgcagagga actcgccagt ttcatcaaac agttcggtcg ggaacggacc tgcccccaca
     4441 cgagtggagt aagctttgag gatacccaga acgtaatcaa cataacgcgg gcccaggccg
     4501 gaaccggtcg ccacgccacc agcagtggtg ttggaagaag ttacgtacgg atatgtaccg
     4561 tggtcgatat ccagcagcgt accctgcgca ccttcaaaca tgacgaaatc gccacgctga
     4621 cgcgcctggt cgagcaggtc agaaacgtca acaaccatag aagtcaggat gtcggcaaca
     4681 gccatcgtat catccagaac tttctggtaa tcaaccgctt cagctttgta gtagttaacc
     4741 aactggaagt tgtgatattc catcacttct ttcagttttt cagcgaaggt ttctttgtcg
     4801 aaaaggtcgc caacacgcag accgcgacgt gctactttat cttcataagc aggcccgata
     4861 ccacgaccgg tggtgccgat cgctttcgcg ccacgcgctt tctcacgcgc gttatccagc
     4921 gcaacgtgat aatcaaggat cagcggacat gcttcggaca gcagcagacg ctcacgaacg
     4981 gggatgccac ggtcttccag ttctttcatc tctttcatca gcgcagccgg agacagcaca
     5041 acaccgttac cgatgatgct ggttacattc tcgcggagaa tacctgatgg aataagatgg
     5101 agaacggttt tttcaccgtt gattacgaga gtatggcctg cgttgtgacc gccctggtag
     5161 cgtacaacat atttagcccg ttcagtcaga agatcgacga tcttaccttt accttcgtca
     5221 ccccattggg tgcccagtac gacgacgttg ttacccattt ttcaaaatca ccgtttgctt
     5281 aaaaatggat tctaccatcg ctttttcaga gttacagcac tttttgcact caaaaatgac
     5341 ctcgatcagt ctgttttttg ttcagccaat cgttttcctc aacatgtagt agaccacaac
     5401 gcccgcaacc acaagtccac cgccaaaacg acgtaaaata ttatcgggca aattggtcat
     5461 cgcagagatc atcttcttcc atgccttcgg gtaaagcatc ggccctaaac cttccagtac
     5521 caaaaccagg gcaagcgcca gccagattgt cgaattcatt cattatcctt atagaaaaag
     5581 aaaaccaccg acatccctga ggatgcggtg gctttattga cctgtaccgc agtcgttata
     5641 ttaacgcgtt gcggaagtcg gcgtcttcat gtagcggaag aaatcgctgt ccgggctcat
     5701 gaccatcacg tcctgattgc cagagaagct gttctcataa gcacgcaggc tacggatgaa
     5761 tgcgtagaag tccggatctt tactgaatgc atcagcaaac agtttggctg cttctgcatc
     5821 gccttcacca cgcatgatgc ggccctgacg ctcagcttct gccagcgttc tggtcacttc
     5881 atagtcggca gtcgcgcgca gtttttccgc ttcttcctga ccttgtgaac ggtgacgacg
     5941 tgctaccgct tcacgctcgg cgcgcatacg gttgtagatc gcttcagaca cttcggtcgg
     6001 caggttgatc tgcttaattc gcacatcgac aacttcaata cccagcgccg ccatactgtt
     6061 cgggttgatg accggaactt tgcccttcgt ctcagccgtt acgcgctctg ccgcttcggc
     6121 aatggcgtta tctgctgcag gggtagtaac ttcatcttct gtacccgcag aaccggagtt
     6181 cagcgcgtca cgtacttcga gggtcagacg accacgggaa tcggtgacga tatctttcac
     6241 gtccaggcga ccaatttcag aacgcagacg gtcagagaac ttacgtttca acagcacttc
     6301 cgcttgcgaa atgtcgccac cacccgttgc cagatagtaa cggctgaaat cgctgatgcg
     6361 ccatttgatg taagagtcga cgatcaggtc tttcttctct ttggtcacaa agcggtcggc
     6421 ctggttgtcc atggtctgaa tacgtgcgtc gagcattttc accgtttcaa tgaacggtat
     6481 cttgaaatgc agacccggct cataaaccag aggtttgttg tcatcgtcac gcagtacctt
     6541 accaaaacgc agcgtaatac cgcgctcacc ttctttgacg acaaagacag acatgtaaag
     6601 cactaccagc acgatgatga taatcgcgat aactgactta cgcatcgtta ttccccctga
     6661 cgctggtagt cgttacgctg cgcgttggcg cggcgttggt ccataatatc gccctgactg
     6721 gtggacgacg tgttgcttgc tccactggtt gtggaggaag aggctggcgg cagacgcagc
     6781 agattgctgg caccgttatc gctcttcgcc gcaggggcgt taccaccttt cagcatctgg
     6841 tctaatggca gaaccatcag gttgccacct ttatcgttaa ccagcacttt gcgggtgttg
     6901 cccaacactt tttccatcgt ctcgatatac agacgctcgc gagtaatttc cggcgcggct
     6961 ttatattccg gcagaagttt agcaaagcgc gccacttcac cctgagcttc caggatggtc
     7021 tgggccttgt acgcacgcgc ctcttcgagg atacgttgcg cctgaccgtt cgcacgcggc
     7081 tgaacttcgt tggtatacgc ttctgcttca cgaatgtatt gctgttcgtt ttcacgcgcg
     7141 gcaatcgcat cgtcaaacgc cgcttttact tcttccggcg gacgagcagc ctggaagttg
     7201 acgtccagca gcgtgatacc catgtcatac ggacgaatcg tctcttccag ttcgcgctga
     7261 gtatcgctac gaatcacggt acgaccttcc gtcagaatgc ggtccatggt gtatttaccg
     7321 ataaccccgc gtagggcgct gtcggtagcc tgacgcaggc tgtcatccgg gctggtcacg
     7381 ctatacagat atttttccgg atcggtgacg cggtactgca cgttcatctc aacgcgcact
     7441 acgttctcgt ccgacgtcag catcacacca gaagctgcca gttcacgcac ggcttccacg
     7501 ttcaccggtt tgacttcgtc aataaacgtc ggtttccagt tcagacccgg ctcaaccaga
     7561 tggctgaatt taccaaagcg tgttaccacg ccgcgttcgg cttctttaat ggtatagaaa
     7621 ccactggccg cccagataat gacaatcgct gccgctgcga tggtaacgac gcgaccgcca
     7681 agctgcgggc gcgggccttg cgatgaactg ccaccgccag atccggtgcc tttaccgcca
     7741 cccagaccac cgagcttttt gctcagtttg cggaagatat catctaaatc aggtggccct
     7801 tgatcgcgac cgcctttgtt tccatttccc tcagagttgc cgccaggttt gctgcttccc
     7861 cacgggtcgc ggtcttgtcc gttattaccg ggctgattcc acgccatgtt tgtgctccat
     7921 atttgttatg cggtgatccc tgttgtcttt cgacgccaga ggatatgact ccacgcttca
     7981 gacgctacgc cgttagatca ggtaatcgat caacgccggt tcttgtttac agaggcgacg
     8041 ccagtcaacg atcggcatac gaacttgcag acttacgctg ccgtcctcct ccatccactc
     8101 tttttctatt gcctgaagct gataaaaacg acttctcaga cgcccttcct gcggcggcag
     8161 acgcaatgta tgctgcgcca cctcgccgga aagacgctcc gtcaaagcct gaaaaagctg
     8221 tggtatcccc gctccggtct gcgcagaaag ccagacacgg atcggtttgt tctcttcatc
     8281 tctgtcaata cgcggttcga aatcgtccag catatcgatc ttgttcatca ccagcagggt
     8341 tgggatctcg tgagcatcaa tctcttcaag aaccgtattc accgcttcga tgttttcttg
     8401 tacacgcaca tccgccgcgt caatgacgtg cagcagcaat gtggcttgcc gcgtctcttg
     8461 taacgtggct ttaaatgccg ccaccagatc gtgcggcagg tggcgaataa accctacggt
     8521 atctgccaac acggtttcac cgacatccgc aacgtcaata cgccgcaacg tcgggtcgag
     8581 ggtggcaaac aactggtctg ccgcgtagac ccgcgcttcg gtgatgcgat tgaaaagggt
     8641 agatttaccg gcgttggtat atcccaccag cgaaacagta ggaacatcgg ctttgatacg
     8701 cgattgccgc ccctgctcac gctgcttttc aactctttcc aggcgcgact gtatctgcac
     8761 gatgcgatta cgcaacaaac gacggtcggt ttcgagctgg gtttcacccg gaccacgcaa
     8821 accgatcccg cctttctgtc tttcaaggtg ggtccagcca cgcaccaggc gcgtagccag
     8881 atggcgcaac tgcgccagct caacctgcaa cttaccctca tgggtacgcg cacgttgggc
     8941 gaaaatatct aaaataaggc cggtgcggtc gatgacacga cactcgcaca aacgctccag
     9001 gttacgctct tgcgccgggc tcagggcatg gtcaaaaaga acgaccgaag cacccgtcgc
     9061 ttttacggct tccgcaattt caactgcttt accttcacct acaaaatact ttgggtgcgg
     9121 cgctttacgg ctaccggtaa tcacctgcaa tgcttcgaca ccggcggaag agaccagaga
     9181 ttcaaactcc tggaggtctt ccatatcttt gtcttgcgta aaatagatgt gtaccagtac
     9241 cgcctgctca ccagcatcat aacggtcaaa caagcgtata accctctaaa tagatcagcg
     9301 gggaacgcag gatcgctggc tccccgtgta aaaaaacagc ccgaaacctt attcggtttc
     9361 ttcgctgtcc tgttgcgcgg aagtattctg cgcgctgcta ccatgatgat agttactgct
     9421 ggtaccgcca ccggcgttgt tactgtgatg agaaaccggg cgagacggga caacagtaga
     9481 aatcgcgtgc ttgtaaacca tctggctgac cgtgtttttc aacaggatca cgaactgatc
     9541 aaaagactcg atttgtcctt gcagcttaat accattcacc aaataaatag aaactggaac
     9601 acgttcccga cgcagtgcgt tcaggaacgg atcttgtaaa gattgcccct tagccattct
     9661 ctcttttcct tatatgctta tttgtacttt gaacctttcg attctgaaaa aattgcgcac
     9721 gatacgtctc aattgtacac attcagcctg cgatagcacc aacaacctgt aatacttcgt
     9781 cacgcgcctg ttctggtttt tcactgtcaa gccagtgaac cccttcccaa ccacgcagcc
     9841 aggttatctg ccgcttcgcc aactgtctcg tggcgcaaac acctcgataa accatttcat
     9901 cgtatgagat ttcgccttca aggtaagacc acatctggcg ataacccacg caacgaatgg
     9961 aaggcaaatc cgtatgcaaa tctcctcggg caaaaagcgc ccggacttct gcttcaaaac
    10021 ctgaagccaa catctgatga aaacgctgct caattcgttg atggagcagt tcacggctcg
    10081 ccggggcgat ggcgaactga tgcacctgat acggtagagc gtctcctgac gtttgcgtca
    10141 gttccgttaa agttttaccc gaaatgaaaa aaacttccag tgcccgggaa agcctttgtg
    10201 gatcatttgg atgaatcctt gctgccgcaa ccggatctac ctcctgaagt tgacgatgca
    10261 atgactccca accttgctct gccgcctgtt gctcaattct ggcccgtact tccgggtccg
    10321 ccgacggtag cggcgacaac ccttccagca atgccttgaa atacaacatc gtaccgccca
    10381 ctaatagtgg gatccgcccc gccgcggtga tatcggccat ttccgccagc gcatcgcggc
    10441 gaaaatcagc agccgagtaa gcctgcgacg gatcgcgaat attcagcaat cggtgcggcg
    10501 cggcgagtaa ctcttcagcg ttcggcttcg ccgtcccgat atccatccct ttgtaaataa
    10561 gggcagaatc aacgcttatc aactctactg gtaaaatttt acgcagctca atggctaacg
    10621 ctgttttacc ggaggccgtc ggccccatca aaaaaatcgc cttaggcagg ctcgccttac
    10681 tgatatcact catctttcag ggcttttatc gccggatgta aatcaacaga ttgtaacaga
    10741 ccacccggcg gcgttttcac aagttgcgga cataaccgtt ccacgtccgc cagcagggtt
    10801 atggcctgtg ccattgacca ctgcgcatgt tcgctcatca gatttcgtgc aatccactgc
    10861 gcaatattgc caggttcgaa tacggactgc ttcgccaggt agcctatcag ttcaggaatc
    10921 aagatttgta aattttgttg gcgtaagggt aaaggcacgg ccctgatggt cacatgctgc
    10981 gcatcggact ggaaatcaat acccaattcc gccagggcag actgcgcttt ttctaatgcc
    11041 gatttttctt cgccagaaac ttttagccgc aacggaataa gcagcggttg ggcgcaaact
    11101 ggcacttcac ccggcgtcaa ttgtgcctga cgcagccaac gttctgccac tggcaaggat
    11161 aaaagtgaaa tgttgccatc gcgctcaagc aacgcacagt cggaatggac gatagtcagt
    11221 acccgaccaa aactctgact gttcgccgca agtgcaggtt cctgcggttc tggcgctttt
    11281 ggtttttgca tcggcgcggg cgtttgcaaa agctggcgat acacttcacc ttgctgtttc
    11341 tggtaacctg gctgcgcatt cggccagggg gcagccggac gactgcctga ggagggcgca
    11401 ggagtgtaac gcggagctac tggctcacga actgccggtt cagcaaaatg attgcgcccc
    11461 gccgccacgc gattttccgg aatggcacgc ggtgcaggtt gtggttcatc gtccagcggt
    11521 agcggcgttt ccagttgctg ttgtagcacg ctcagcacgc cctgatagat aaagtcatgc
    11581 accagacgcg actgatggaa acgcacttcg tgtttggcag ggtgcacgtt gacgtccacc
    11641 tgatgcgggt cgatctccag atacaacaca aatgccggtt gctgatcggc ccccagtttg
    11701 tcttcgcagg cctggcggat cgcgtgattg atcaggcgat cgcgcatcat gcgaccgttc
    11761 acgtagcaat actgaatttc tgccagtgcg ggcgtggtgt gatttggatc ggccacccag
    11821 ccgcgcagcg tgagatcgcc gtgttgccat tcaatcgcca gcgcttgttc gagaaaagcg
    11881 gtgccgcaaa tcgcgcctaa gcgccgttct ttttgcccgc cttccggcac tgcgcggtac
    11941 tggcgtacaa ttttgccgtt atgcgacagg ttgatagtga cgtcgaaacg cgccagcgca
    12001 atgcggcgga tgatttcatc gatatggtta aattcggttt tctcggtgcg caggaatttg
    12061 cgccgcgccg gggtgttgta gaacaggtcc agcacctcca gcgtcgttcc caccggatgc
    12121 gccgccggtt taaccgtcac gtccatattg cgcccttcgg cataagcctg ccaggcttcc
    12181 tgctgttctg cggtgcgtga agtgagcgtc aggcgggaaa ccgaactgat actcgccagt
    12241 gcctcaccgc gaaagcccag gctgataatg gcttcgagat cgtccagaga ggcgatttta
    12301 ctggtggcat gacgcgccag cgccagtgcc agctcatctt ttttgatacc gcagccgtta
    12361 tcacgaatgc ggataagttt cgccccaccg cgttcgatat caatatcgat acgcgtcgca
    12421 cctgcatcga ggctgttttc caccagttct ttgactaccg acgcaggtcg ctcgaccacc
    12481 tcacctgcgg caatctggtt cgccagttgt ggcggtaaga cctgaattgg catcaatcgt
    12541 ccttagtttg gcagcgtgcg atctggcgtc gtcaccgtac tggccgtttg tgccgttgca
    12601 ccctgcggcg cagattgcat cggatgcgca aggaagtaat tgcgcaggcc tttgtaaatg
    12661 gcttctgcca gctgttgttg gtaatcgtcg ctcgccagca aacgttcttc gctgttgtta
    12721 ctgataaaac cggtttcgac cagtactgac ggaatatccg gcgaacgcag aacgccgaga
    12781 ctcgcgtgtt ctggtcggcg tttatgtatt tcgccaatgc gttgcaactg actgatcata
    12841 ctggtcgcta catcataccc tacccgctgg gaatgaccga actgtaaatc cagcaccgcc
    12901 tggcttaaat aggggtcggc ctgactgttc gccagcacat cacccgcccc gcccagcagc
    12961 tccgactgct tctcatgctg ttccagccag ctggccattt cgctgttggc gcgacggttt
    13021 gagagcaccc atacagaggc accggtggca ctacggtttg gtgcggcatc ggcatgaatc
    13081 gacacaagga aattggcgtt ttgcttacgt gccacatcac tgcgccccat caccgagata
    13141 aagtaatccc cgtcacgggt taaaacgccc ttaaacatcg gatcgttatt gagcaaggta
    13201 cgtaatttac gcgcaatggc gatggtgaca tttttctccc gtgtaccacc agggccgata
    13261 gcgccagggt cctgaccgcc gtgtccggca tcaatagcga tgataatttt atcgcctgtg
    13321 ttagccgtcg cgcgcgctgc cggacgcgtt accgtattac tgctgataac acccgtagtg
    13381 cggttacttt ccgttttaaa cggattgcgc gccggttcgc tgacgcgcgg tgcgacaacc
    13441 gcaggcgttt caacgcgttt cgcaaccatt ggcggaggcg atggcggcgc atcggcgtta
    13501 atcgtaaaga caacagtgta attgctgcca ttctgccgct tcaccgcttc ggttttaccg
    13561 ttttcggtga gatcgaccac cagccgtagc gtttgtgcat ctttaggcgt tccggagcga
    13621 atcgctttca ccaggttatt accgctaaac aacaacggca gcccctgaat tacccccgtt
    13681 tgtttgatat cgagcgccac ggtgcgtttg ctttgatggc taaacgcata atcaggatcg
    13741 ccaataaaac tcaacgttat ccgcgcctgt tgattaccgt tagaaacctg aatatcagag
    13801 agcgtcgcgg cccccgcctg cgcgcacagc agcagcaacg tcgctactaa ccaatttctg
    13861 atgcgataca tcatcccgcc acctttcaaa ggttaaccgg ctaaacgcgc cagcaacaat
    13921 tcacccgcag aggaaaccgc actcacgcgc gcctcacggc cttgtgcctg ataatcaatg
    13981 tgtatttcga catccgggtc aggaagaaca cctgtacctt gttgtggcca ctccaccagg
    14041 cagatggcat cgttggcaaa ataatcgcgg atccccataa actccagctc ctcgggatcg
    14101 gcaaggcggt acaaatcaaa gtgataaacc attaaattgt cgagcgtata gggttcgacc
    14161 agcgtataag tggggctttt gacattaccc tgatgaccca gagcctgtaa aaagccccgg
    14221 ctaaaggtgg ttttacctgc gcctaaatcg ccatacagat agattacggt tgcgccatcg
    14281 caggctttcg ctacccgctc gcccaggtct aatgttgcct gctcatcagg gagcggaatt
    14341 actcgattca tcatggtttt tatcagtcac ttccgggtta acaatacgct gtagcgtgga
    14401 aaagagatcg gttgccagca tcccgcgcgt tccaaaacgc gccgccagta cgtcagctgc
    14461 cgcaccgtgc gcgacacagc ccgcacaggc tgcatcataa gggctcattt tttgcccaag
    14521 caatgcgcca ataataccag agagcacatc gcccatgccg ccgctcgcca tgcctgcatt
    14581 tccggcatca ataatgccta aagcgtcagg atgggcggcg accacggttc cggcaccttt
    14641 cagcaccgct acgccgccat aacgttgtac cagacgttgg gcgcaatgta agcggtcact
    14701 ttcaatttca gcgacggaac atcctaacaa ccgtgcggcc tcaccaggat gcggcgtgat
    14761 cacgcgattg tgacgcttat cgggattgat tgccagcagg ttcaatgcat cggcatccca
    14821 caacatcggt ttgcgaaaat tctcaacttt ttgcagggct tttttccccc actcttgctg
    14881 gcccagaccg ggaccaatca ccaccacatc ggcccattcc aggctttcgg taagagagcc
    14941 catagtcagt tcatgcacca tcaattccgg tcgtgcagtc agcagcggcg caatgttctc
    15001 actgcgggtc agtactcgga ctaaaccagc accagcacgc agcgccgctt cccccgtcat
    15061 acgaatagcc cccgccgtgc cgtgatcgcc accaataatc accagccgcc cgtgatcgcc
    15121 tttatgcgaa gtcgggcgac gcggtatcag ccactgagaa agttgttctg ccgaaaaccg
    15181 ctgaattttc gtctcctgac ctgccagcca tctatccagc cgcagtgagt caaaatgcag
    15241 ttgtccggta acatcccgcg cttttccagt gagcaaacct ggtttcagcg caataaaagt
    15301 gatggtgtga tcggcgttga ttaccgcgcc tggcgtagcg ccggtttcag ccagaaggcc
    15361 ggaagggata tcaaccgcca caatcggcgc aggatgggaa ttagcgtggt cgattaactg
    15421 gctaatggat tcgcggggcg cttgctgcaa accggtgccg agcagcgcat cgacaatcag
    15481 atctaccgat tcgggccaga caatattcga agcatggatc tcgcctcccg cgtttaacca
    15541 tgcttcgcgt gccagcgcgg cctcttccgg caacggtttg tcactttcct gggccagcag
    15601 cgtgacatca ataccgatcg ctttggccag ccgcgcgacc acgtagccat cgccgccgtt
    15661 attaccatga ccgcacagca ccagccagtg gcgggcgtca ggataagccg aacgacacac
    15721 ctggaatgcg gcttcgccag cgcgaagcat cagctcatag agtgtgagcc ccagcgcatc
    15781 tgccgcctcg cgttctccgc ggcggatatc gtcggcgtac cagacggtgt gtggtatact
    15841 tacggggttt ttcttcattg tatggtccgt catgtcagag cccctcgatc tcaatcagtt
    15901 agcgcaaaaa attaaacagt gggggctgga actgggcttt cagcaggtag gtattaccga
    15961 taccgatctc agcgagtccg agcccaaact gcaagcatgg ctggacaaac aataccacgg
    16021 cgaaatggac tggatggcgc gtcacggtat gctgcgtgct cgtcctcacg aattattgcc
    16081 cggtacgctg cgcgtgatca gcgtgcggat gaattacctt cctgctaacg ccgcatttgc
    16141 cagcacgctg aaaaatccca aactcggcta tgttagccgt tatgcgctgg gccgtgacta
    16201 tcacaagctt ctgcgcaacc gactcaaaaa gctgggcgag atgattcagc aacattgtgt
    16261 ttcgctgaat tttagaccgt ttgtcgattc tgcgcctatt ctcgagcgcc cgttagctga
    16321 aaaagcaggt cttggctgga caggtaagca ctcacttatc ctcaatcgcg aggccggttc
    16381 gttcttcttt ttaggcgaat tgctggtcga tattccgctg cccgtggatc aaccagtcga
    16441 ggaaggatgc ggtaaatgcg tggcctgtat gacgatttgc ccgaccggtg ccatcgtcga
    16501 gccatatacc gtcgatgctc gccgctgtat ctcttatctc accatcgaac tggaagggga
    16561 gatcccggaa gagttgcgac cgttaatggg aaaccgtatt tacggttgcg atgactgcca
    16621 gcttatctgc ccgtggaatc gctattcgca actcactaca gaagacgatt tcagcccgcg
    16681 taagccgcta cacgcaccgg aactcattga gttattcgcc tggagtgaag agaagttttt
    16741 aaaagtcacg gaaggttcgg cgattcgccg tataggtcac ctgcgttggc tgcgtaatat
    16801 cgccgtagca ttaggcaatg ccccctggga tgaaacgatt ttgacagcgc tggaaagtcg
    16861 taaaggtgag cacccacttc ttgatgagca catagcgtgg gcgattgcgc agcaaatcga
    16921 gagacgaaat gcgtgcgtgg tcgaagtgca attaccgaaa aaacagcgtc tggttcgggt
    16981 gattgaaaaa gggttaccgc gtgacgcctg attcatccac agcttgtgaa taaaaataaa
    17041 aacgcattgc aattcaagcc ggaaaaaatc gtcaagtgat cgatacgaca aaacgaaatc
    17101 ttaattttta acttatctat caataggtta aaaaaatact attcaccgtg cgaagtttct
    17161 ttgaaattaa gattacggcc tgaggctgtg gataactctg tttacaagag tttgtcagag
    17221 acaacaaaaa ccagcaataa cgcatcgcgt cgctgtggat attttattga gagaagaatt
    17281 tggagcggga aacgagactc gaactcgcga ccccgacctt ggcaaggtcg tgctctacca
    17341 actgagctat tcccgcttgg gtggtctgtg ctttacagca ctttcaaatt ttggagcggg
    17401 aaacgagact cgaactcgcg accccgacct t
//
LOCUS       DAPOXO010000099        17236 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.099, whole genome shotgun sequence.
ACCESSION   DAPOXO010000099 DAPOXO010000000
VERSION     DAPOXO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17236
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.099"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(722..1258)
                     /gene="yghD"
                     /locus_tag="ROH59_004166"
     CDS             complement(722..1258)
                     /gene="yghD"
                     /locus_tag="ROH59_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspM family type II secretion system protein
                     YghD"
                     /protein_id="HDX4806582.1"
                     /translation="MLRDKFIHYFQQWRERQLSRGEHWLAQHLAGRSPREKGMLLAAA
                     VFLFCAVYYVLIWQPLSERIEQQETMLQQLVAMNARLKSTAPDIIAARKSGTTTQAQV
                     SRVISDSASAHSVVIKRIAERGENIQVWIEPVVFNDLLKWLNALDEKYALRVTQIDVS
                     AAEKPGMVNVLRLEFGRG"
     gene            complement(1260..2438)
                     /gene="gspL"
                     /locus_tag="ROH59_004167"
     CDS             complement(1260..2438)
                     /gene="gspL"
                     /locus_tag="ROH59_004167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HDX4806583.1"
                     /translation="MSSILEIFFPLCDSDTVRWQRRTPDVEHGIWPDVADERLQQWLQ
                     TDAIRLYIPGEWISVWQVELPDVARKQIPTILPALLEEELNQDIDELHFAPLKIDQQL
                     ATVAVIHQQHMRNIAQWLQANGITRATVAPDWMSIPCGYMAGDAQRVICRIDECRGWS
                     AGRALAPVMFRAQLNEQDLPFSLTVVGIAPEELSAWAGADAERLTVTALPAITTYGEP
                     EGNLLTGPWQPRVSYRKQWARWRVMILPILLILVALAVERGVTLWSVSEQVAQSRTQA
                     EKQFLTLFPEQKRIVNLRSQVTMALKKYRPQADDTRLLAELSAIASTLKSASLTDIEM
                     RGFTFDQKRQTLHLQLRAANFASFDKLRSALAADYVVQQDALQKEGDAVSGGVTLRRK
                     "
     gene            complement(2435..3412)
                     /gene="gspK"
                     /locus_tag="ROH59_004168"
     CDS             complement(2435..3412)
                     /gene="gspK"
                     /locus_tag="ROH59_004168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HDX4806584.1"
                     /translation="MITSPPKRGMALVVVLVLLAVMMLVTITLSGRMQQQLGRTRSQQ
                     EYQQALWYSASAESLALSALSLSLKNEKRVHQAQPWASGPRFFPLPQGQIAVTLRDAQ
                     ACFNLNALAQPTTASRPLAVQQLIALISRLDVPAYRAELIAESLWEFIDEDRSVQTRL
                     GREDSEYLARSVPFYAANQPLADISEMRVVQGMDAGLYQKLKPLVCALPMTRQQININ
                     TLDVTQSVILEALFDPWLSPVQARALLQQRPAKGWEDVDQFLAQPLLADVDERTKKQL
                     KTVLSVDSNYFWLRSDITVNEIELTMNSLIVRMGPQHFSVLWHQTGESE"
     gene            complement(3409..4014)
                     /gene="gspJ"
                     /locus_tag="ROH59_004169"
     CDS             complement(3409..4014)
                     /gene="gspJ"
                     /locus_tag="ROH59_004169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HDX4806585.1"
                     /translation="MRRTCAGFTLLEMLVAIAIFASLALMALQVTNGVTRVNSAVAGH
                     DQKLNLMQQTMSFLNHDLTQMMPRPVRGDQGQREPALLAGAGVLASESEGMRFVRGGV
                     VNPLMRLPRSNLLTVGYRIHGGYLERLAWPLTDAAGSVKPTTQKLIPADSLRLQFYDG
                     TRWQESWSSVQAIPVAVRITLHSPQWGEIERIWLLRGPQLS"
     gene            complement(4011..4382)
                     /gene="gspI"
                     /locus_tag="ROH59_004170"
     CDS             complement(4011..4382)
                     /gene="gspI"
                     /locus_tag="ROH59_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HDX4806586.1"
                     /translation="MKRGFTLLEVMLALAIFALAAMAVLQIASGALSNQQILEEKTVA
                     GWVAENQTALLYLMTREQRAVRHQGESDMAGSRWYWRTTPLSTGNALLQAVDIEVSRH
                     EDFSSVIQSRRAWFSAVGGQQ"
     gene            complement(4379..4942)
                     /gene="gspH"
                     /locus_tag="ROH59_004171"
     CDS             complement(4379..4942)
                     /gene="gspH"
                     /locus_tag="ROH59_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001394829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HDX4806587.1"
                     /translation="MPERGFTLLEIMLVIFLIGLASAGVVQTFATASEPPAKKAAQDF
                     LTRFAQFKDRAVIEGQTLGVLIDPPGYQFMQRRHGQWLPVSATRLSAQVTVPKQVQML
                     LQPGSDIWQKEYALELQRRRLTLHDIELELQKEAKKKTPQIRFSPFEPATPFTLRFYA
                     SAQNACWAVKLAHDGVLSLNQCDEGMP"
     gene            complement(4946..5401)
                     /gene="gspG"
                     /locus_tag="ROH59_004172"
     CDS             complement(4946..5401)
                     /gene="gspG"
                     /locus_tag="ROH59_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003912123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HDX4806588.1"
                     /translation="MNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKA
                     DRQKAISDIVALENALDMYRLDNGRYPTTEQGLEALIQQPANMADSRNYRTGGYIKRL
                     PKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ"
     gene            complement(5418..6641)
                     /gene="gspF"
                     /locus_tag="ROH59_004173"
     CDS             complement(5418..6641)
                     /gene="gspF"
                     /locus_tag="ROH59_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HDX4806589.1"
                     /translation="MALFYYQALERNGRKTKGMIEADSARHARQLLRGKELIPVHIEA
                     RLNASTGGMLQRRRHAHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHV
                     KSLGMALRSRIQEGYTLSDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQ
                     RQHLKSRLLQAMLYPLVLLVVATGVVTILLTAVVPKIIEQFDHLGHALPASTRMLIAM
                     SDTLQTSGVYWLAGLLGLLVLGQRLLKNPAMRLRWDKTLLRLPVTGRVARGLNTARFS
                     RTLSILTASSVPLLEGIQTAAAVSANRYVEQQLLLAADRVREGSSLRAALAELRLFPP
                     MMLYMIASGEQSGELETMLEQAAVNQEREFDTQVGLALGLFEPALVVMMAGVVLFIVI
                     AILEPMLQLNNMVGM"
     gene            complement(6641..8134)
                     /gene="gspE"
                     /locus_tag="ROH59_004174"
     CDS             complement(6641..8134)
                     /gene="gspE"
                     /locus_tag="ROH59_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HDX4806590.1"
                     /translation="MVPVAQETTANTVRLPYSFSRRFSLVAWCEASLEILHVHPLSLS
                     VLQELQRGLNASFTLRQIDEAEFEQRLNAVWQRDSSEARQLMEDLGSAEDFFTLAEEL
                     PETEDLLESDDDAPIIKLINAMLAEAIKEGASDIHIETFEKSLVIRFRVDGTLHEMLR
                     PGRKLASLLVSRIKVMARLDIAEKRVPQDGRIALLLGGRAIDVRVSTMPSAWGERVVL
                     RLLDKNQARLTLERLGLSLELTAQLRQLLHKPHGIFLVTGPTGSGKSTTLYAGLQELN
                     NHSRNILTVEDPIEYMIEGIGQTQVNTRVGMTFARGLRAILRQDPDVVMVGEIRDTET
                     AEIAVQASLTGHLVLSTLHTNTAVGAITRLQDMGVEPFLLSSSLTGVMAQRLVRTLCP
                     DCRQSAPATDEEKRLLGITDARTVTLYHPQGCPACNHKGFRGRTAIHELIVVDATLRD
                     LIHRQAGELELERYVRQHSAGIRSNGIEKVLAGETSLDEVLRVTMEA"
     gene            complement(8134..10194)
                     /gene="gspD"
                     /locus_tag="ROH59_004175"
     CDS             complement(8134..10194)
                     /gene="gspD"
                     /locus_tag="ROH59_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HDX4806591.1"
                     /translation="MFWRDMTLSVWRKKTTGLKTKKRLLALVLAAALCSSPVWAEEAT
                     FTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRTMTPLNERQYYQLFLNLLEA
                     QGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEMVTKVVPVRNVSVRELAP
                     ILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVDHAGNRTEEVIPLDNA
                     SASEIARVLESLTKNSGENQPATLKSQIVADERTNSVIVSGDPATRDKMRRLIRRLDS
                     EMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSGREVVSIAASKHS
                     NALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGVQWASKDAGLM
                     QFANGTQIPIGTLGAAISQAKPQKGSTVISENGATTINPDTNGDLSTLAQLLSGFSGT
                     AVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTGSTVGSNN
                     SNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTSLDVVFGERKLKTTV
                     LANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNLMVFIRPTI
                     LRDGMAADGVSQRKYNYMRAEQIYRDEQGLSLMPHTAQPVLPAQNQALPPEVRAFLNA
                     GRTR"
     gene            complement(10224..11183)
                     /gene="gspC"
                     /locus_tag="ROH59_004176"
     CDS             complement(10224..11183)
                     /gene="gspC"
                     /locus_tag="ROH59_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HDX4806592.1"
                     /translation="MARVVFRDARIYLIQLLTKIRHTLSQRQSLNTDKEHLRKMVRGM
                     FWLMLLIISAKMAYSLWRYFSFSAEYTAVSSSANKPLRADAKPFDKNDVQLVSQQNWF
                     GKYQPVAAPVKQPEPAPVAETRLNVVLRGIAFGARPGAVIKEGGKQQVYLQGERLGSH
                     NAVIEEINRDHVMLRYQGKMERLSLAEEKRPTKAVTSKKAVSDEAKQAVAEPAASAPV
                     EIPAAVRQALAKDPQKIFNYIQLTPVRKEGIVGYAVKPGADRSLFDASGFKEGDIAIA
                     LNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARYDISIALR"
     gene            complement(11201..11611)
                     /gene="gspS2"
                     /locus_tag="ROH59_004177"
     CDS             complement(11201..11611)
                     /gene="gspS2"
                     /locus_tag="ROH59_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system pilot lipoprotein
                     GspS-beta"
                     /protein_id="HDX4806593.1"
                     /translation="MSIKQMPGRVLISLLLSVTGLLSGCAGHNENASLLAKKQAQNIS
                     QNLPIKSAGYTLVLAQSSGTTVKMTIISEAGAQTTQTPDAFLTSYQRQMCADPTVKLM
                     ITEGINYSITINDTRTGNQYQRKLDRTTCGIVKA"
     gene            complement(11677..12486)
                     /gene="pppA"
                     /locus_tag="ROH59_004178"
     CDS             complement(11677..12486)
                     /gene="pppA"
                     /locus_tag="ROH59_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417446.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase PppA"
                     /protein_id="HDX4806594.1"
                     /translation="MLFDVFQQYSAGMPILATVGGLIIGSFLNVVIWRYPIMLRQQMA
                     EFHGEMPSTQSKINLALPRSHCPHCQQTIRVRDNIPLLSWLMLKGRCRDCQAKISKRY
                     PLVELLTALAFLLASLVWPESGWGLAVMILSAWLIAASVIDLDNQWLPDVFTQGVLWT
                     GLIAAWAQQSPLTLQDAVTGVLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGGW
                     VGPLSLPNVALIASCCGLIYAVITKRGSTTLPFGPCLSLGGIATLYLQALF"
     gene            complement(12616..17172)
                     /gene="sslE"
                     /locus_tag="ROH59_004179"
     CDS             complement(12616..17172)
                     /gene="sslE"
                     /locus_tag="ROH59_004179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein metalloprotease SslE"
                     /protein_id="HDX4806595.1"
                     /translation="MNKKFKYKKSLLAAILSATLLAGCDGGGSGSSSDTPPVDSGTGS
                     LPEVKPDPTPNPEPTPEPTPDPEPTPEPTPDPEPEPEPEPVPTKTGYLTLGGSQRVTG
                     ATCNGESSDGFTFTPGEDVTCVAGNTTIATFDTQSEAARSLRAVEKVSFSLEDAQELA
                     ASDDKKSNAVSLVTSSNSCPANTEQVCLTFSSVIESKRFDSLYKQIDLAPEEFKKLVN
                     EEVENNAATDKAPSTHTSPVVPVTTPGTKPDLNASFVSANAEQFYQYQPTEIILSEGR
                     LVDSMGNGVVGVNYYTSSGRGVTGENGKFNFSWGETISFGIDTFELGSVRGNKSTIAL
                     TELGDEVRGANIDQLIHRYSQAGKNDEREVPDVVRKVFAEYPNVINEIINLSLSNGEA
                     LSEGDQTFERTNEFLEQFESGQAKEIDTAICDSLGGCNSQRWFSLTARNVNEGQIQGV
                     INKLWGVDKDYKSVTKFHVFHDSTNFYGSTGNARGQAVVNISNAAFPILMARNDKNYW
                     LAFGEKRAWDKNELAYITEAPSLVEPENVTRDTATFNLPFISLGQVGEGKLMVIGNPH
                     YNSILRCPNGYSWEGGVDKNGQCTRNSDSNDMKHFMQNVLRYLSDDKWTPDAKASMTV
                     GTNLDTVYFKRHGQVTGNSAEFGFHPDFAGISVEHLSSYGDLDPQEMPLLILNGFEYV
                     TQVGNDPYAIPLRADTSKPKLTQQDVTDLIAYLNKGGSVLIMENVMSNLKEESASGFV
                     RLLDAAGLSMALNKSVVNNDPQGYPNRVRQQRATGIWVYERYPAVDGALPYTIDSKTG
                     EVKWKYQVENKPDDKPKLEVASWLEDVDGKQETRYAFIDEADHKTEDSLKAAKAKIFE
                     KFPGLKECKDPTYHYEVNCLEYRPGTGVPVTGGMYVPQYTQLSLNADTAKAMVQAADL
                     GTNIQRLYQHELYFRTNGRKGERLSSVDLERLYQNVSVWLWNKIEYRYENDKDDELGF
                     KTFTEFLNCYANDAYTGGTQCSDELKKSLVDNNMIYGEKSVNKAGMMNPSYPLNYMEK
                     PLTRLMLGRSWWDLNIKVDVEKYPGAVSAEGEKVTETISLYSNPTKWFAGNMQSTGLW
                     APAQKEVTIESSASVPVTVTVALADDLTGREKHEVALNRPPKVTKTYDLKANDKVTFK
                     VPYGGLIYIKGNSPKNESAEFTFTGVVKAPFYKDGEWKNALNSPAPLGELESDAFVYT
                     TPKKNLEASNFTGGVAEFAKDLDTFASSMNDFYGRNDEDGKHRMFTYKNLTGHKHRFT
                     NDVQISIGDAHSGYPVMNSSFSTNSTTLPTTPLNDWLIWHEVGHNAAETPLTVPGATE
                     VANNVLALYMQDRYLGKMNRVADDITVAPEYLEESNGQAWARGGAGDRLLMYAQLKEW
                     AEKNFDIKQWYPEGDLPEFYSDREGMKGWNLFQLMHRKARGDDVGKTKFGERNYCAES
                     NGNAADKLMLCASWVAQTDLSEFFKKWNPGANAYQLPGASEMNFEGGVSQSAYETLAA
                     LNLPKPQQGPETINQVTEHKMSAE"
BASE COUNT         3857 a         4880 c         4271 g         4228 t
ORIGIN      
        1 tttatgcgta acaatacctg caatccgttt caaaccagaa cgcacgcgat tgattaccaa
       61 taaattgttc accaagaaac tatttcccta tttaaaattc actcgtgtac ttcttattta
      121 tatctacagc cccctcttta cagccatatt tgtgatttat atcacattta aatggtgtta
      181 tttaagtcgc accaataatc ccgaaggtaa ttattttcgt cgattaaaat atacatcttg
      241 attattttgt gtatttattt taaccagtgt tacaaccaac accatccctc agtagatata
      301 cctgagcaga catttcttaa aatcgacgaa tagtttcact ggaaattatt atgcttattt
      361 gaaattccct ttctgattat ctccaggaat tttactaatt tccaagcaac acaaaataca
      421 gatcacacaa gaattatcct atatgttttg acctatcaat tgttactcaa tgatttatta
      481 caactattaa taatcataat gtgtcaaaac acttaagcat ctttacagtc ttagaaaggt
      541 gtcgattaac gaaggctaca tggtgaaaaa caggttcctt cagtgttacc gaacattccg
      601 tggtggtctg gagggagata aatcttgcta catcggaact cagcccggtg agctggtttg
      661 acagttccgc actcaccatt gggctaaggg ttatcaggtg gggttaagga aatggcaata
      721 cctacccccg tccaaactcc agtcgcagca catttaccat ccctggcttc tcagcagcac
      781 tgacatcaat ttgtgtcacc cgcagcgcat atttttcatc cagtgcgttt aaccatttca
      841 gaaggtcatt aaacaccaca ggttctatcc agacctgaat attctcccca cgctcggcta
      901 tccgcttgat gaccaccgag tgcgcggaag cgctgtcact gatgacccgc gatacctgtg
      961 cttgcgttgt cgtgccggat tttcgcgccg caataatatc cggcgcagtg ctcttcagtc
     1021 gcgcgttcat cgccaccagc tgctgcaaca tcgtctcctg ttgttctatc cgctcgctca
     1081 acggctgcca gatgaggacg taatatacgg cgcaaaacag gaacacggcc gcggccagta
     1141 acatgccttt ttcacgcggc gaacgccccg ccaggtgctg tgccagccag tgttcgccac
     1201 ggcttaactg gcgttcacgc cattgctgaa aatagtgaat aaatttatcg cgtaacatgt
     1261 tatttcctcc gcaacgttac gccgccggaa accgcatcac cctctttctg taacgcgtcc
     1321 tgttgcacaa cataatctgc cgccagtgcg ctacgcagtt tatcgaagct ggcaaagttc
     1381 gcagcccgta gctggaggtg aagcgtctgg cgtttttgat caaaggtgaa accacgcatt
     1441 tcgatgtcgg taagtgacgc tgatttcagg gtactggcga tcgctgacaa ttctgcgagc
     1501 agccgggtat cgtcggcctg tgggcgatat tttttcagcg ccatcgtcac ctgagagcgt
     1561 aaattcacaa tccgcttctg ctccgggaat agcgttaaga actgtttctc cgcctgggtg
     1621 cggctttgcg ccacctgttc gctgacgctc cataacgtca cgccccgttc cactgccagc
     1681 gcaaccagaa tcagcaatat cggcagaatc atcacccgcc agcgcgccca ctgttttcgg
     1741 tagctgacgc gaggctgcca cggtccagtc agcaggttcc cttccggttc gccataagtg
     1801 gtaatggcgg gcagagccgt cactgtcagg cgttcggcgt ctgcaccagc ccatgcagac
     1861 agttcttccg gtgcaatgcc gaccacggtt agtgaaaacg gtaaatcctg ctcattgagc
     1921 tgtgcgcgga acatgaccgg agccagcgcc cgcccggcgc tccatccccg gcattcatcg
     1981 atgcggcaga taacccgttg cgcatcgcca gccatatagc cacaaggaat ggacatccag
     2041 tctggcgcga cggtagcgcg ggtgatgccg tttgcctgca accattgcgc aatgttacgc
     2101 atatgctgtt ggtgaatcac tgctacggtt gccagttgct ggtcgatttt caacggggcg
     2161 aaatgcagtt catcgatatc ctgattcagc tcttcttcca gcaaggcggg cagaatagtc
     2221 ggtatctgct tgcgggcgac atcaggcagt tcaacctgcc agacgctgat ccattcgccg
     2281 ggaatgtaga gtcgaatcgc atcggtttgc agccattgct ggagacgttc gtcagcaacg
     2341 tcaggccaga taccgtgttc cacatcgggt gtacggcgct gccagcggac ggtgtcggag
     2401 tcgcaaagcg ggaaaaaaat ctcaaggatg gaactcactc actttctcct gtctgatgcc
     2461 agagaacaga aaagtgttgt gggcccatgc ggacaattaa cgagttcatc gtcagttcaa
     2521 tctcattcac ggtgatatct gaacgcagcc agaagtaatt gctgtccacg ctcaggacgg
     2581 tttttagctg ttttttagta cgctcatcga cgtctgcgag tagcggctgt gcaagaaact
     2641 gatcgacatc ttcccagccc ttcgccggac gttgttgtaa taacgcccgc gcctgtacag
     2701 ggcttaacca cgggtcaaac agcgcctcaa gaatcacact ttgcgtgaca tccagggtgt
     2761 tgatgttgat ttgctggcgg gtcatcggca gcgcacagac cagcggtttc agtttttgat
     2821 aaagtccggc gtccattccc tgcaccacgc gcatctcact gatatcggcc agcggttgat
     2881 tagcggcgta aaacggcacc gaacgggcga gatactcgct gtcttcacga cccagacgcg
     2941 tctgcacgct gcggtcttcg tcaataaact cccacaggct ttcggctatc agttcggcac
     3001 gataagcagg cacatcgagg cgcgagatca gggcaatcag ttgttgtacc gcgagcggac
     3061 gcgacgccgt cgtcggctga gcgagggcat tcaggttaaa gcaggcctgt gcgtcacgca
     3121 gagtgacggc gatttgcccc tgcggcagtg ggaaaaaacg agggccagaa gcccacggct
     3181 gtgcctgatg cacacgcttt tcatttttca ggctcagact gagtgcgctc aacgccaggc
     3241 tttccgcact ggcgctgtac cacagcgcct gctggtactc ctgctggctg cgcgttcgcc
     3301 caagttgttg ctgcatccgc ccggaaagcg tgatggtcac cagcatcata accgccagca
     3361 ataccagcac cacgaccagt gccattccgc gttttggtgg tgaggtgatc atgataattg
     3421 cggcccgcgt aacaaccaga tgcgttcaat ttcgccccat tgcggcgaat gcagggttat
     3481 gcgtactgcc acaggaatcg cctgcactga tgaccagctc tcctgccagc gcgtgccgtc
     3541 gtagaactgc aaacggagcg aatccgccgg gattaatttt tgcgttgttg gcttcacgct
     3601 gcctgccgca tcggtcagtg gccaggctaa ccgttcgaga taaccaccat gaatgcggta
     3661 accgacggtg agcagattac tgcgcggcag acgcatcaac ggattaacca cgccgccgcg
     3721 cacaaaacgc atcccttcac tctcagacgc cagcacgcca gcgcccgcca gtaacgctgg
     3781 ttcacgctgg ccctgatcgc ctcttaccgg acgcggcatc atttgtgtca gatcgtggtt
     3841 caaaaaactc atcgtttgct gcatgaggtt tagtttttga tcgtgtccgg cgacggcgct
     3901 attcacgcgt gtaacgccgt ttgtcacctg cagcgccatc agtgccagtg aggcaaaaat
     3961 ggcaattgcc accagcattt ccagtaacgt gaaaccagcg caagtccttc tcactgttgg
     4021 cctcccacgg cgctaaacca ggcgcgtcgt gactgaatca ccgacgaaaa gtcttcgtga
     4081 cggctgactt caatatccac tgcctggagc agcgcgttgc ctgtactcag cggtgtggtt
     4141 cgccagtacc agcggcttcc tgccatatca ctctcgccct ggtgcctgac cgctcgttgt
     4201 tcacgggtca tcaggtaaag cagtgcggtc tggttttcag ctacccagcc cgctaccgtt
     4261 ttttcttcaa ggatttgctg attactcagc gcgccgctgg cgatctgtaa caccgccatg
     4321 gcggccaacg caaaaatcgc cagcgcgagc attacttcca gcaaggtaaa tccacgcttc
     4381 atggcatccc ctcatcacat tgattgaggg ataacacgcc atcgtgcgcc agctttaccg
     4441 cccaacacgc gttttgtgcc gacgcgtaaa aacgcagtgt aaacggcgtg gcgggttcaa
     4501 aaggcgaaaa acggatctgc ggtgtcttct ttttcgcctc tttttgcagc tccagttcaa
     4561 tatcgtgcag cgtcaggcga cgacgctgca gctccagcgc atattccttc tgccagatat
     4621 cacttccggg ttgtaacagc atctgcacct gtttcggcac cgtaacctgt gccgataacc
     4681 gggtcgcaga aacgggcaac cattgcccgt gacgacgctg cataaactgg taacctggcg
     4741 ggtcgattag cacaccgagt gtttgccctt cgatcactgc cctgtcctta aactgcgcaa
     4801 agcgagtcag aaaatcctgc gccgcttttt tcgcaggcgg ctctgaagcg gtcgcaaacg
     4861 tctgtaccac gcccgcactg gcaaggccga taaggaaaat caccagcatg atttccagaa
     4921 gtgtgaatcc gcgttcaggc actgattact gaaactcctg caaattccag ttaccgatat
     4981 ctgcgccagc gccctccccg ttttcctgac catctgctcc cagggtataa acatcaaaca
     5041 gccctttttc acccgggctg agatactgat aatcattgcc ccacggatcc tttggcagtc
     5101 gtttaatgta tccaccggta cggtagttac gggaatccgc catattggcc ggttgctgga
     5161 tcagcgcctc cagcccctgt tcggtagtcg gataacgccc gttatccagt cggtacatat
     5221 ccagcgcatt ctccagcgcc acgatatcgc tgatggcttt ttgccgatcg gctttctctt
     5281 tgttgcccaa caggttaggc accaccagac ttgctaggac gccaagaata acaatcacca
     5341 ccatcacttc cagcagggta aaacctgccc gtggtttttg tgtgcgggat aacgaattca
     5401 tgtgataact ccgtaaatta cattccaacc atattgttca gttgcagcat cggttcgagg
     5461 atggcgatga cgataaacag caccacgccc gccatcatca ccaccagcgc cggctcaaac
     5521 agccctaacg ccagccccac ctgggtatca aattcccgtt cctggttgac cgcggcctgt
     5581 tcaagcatgg tttccagttc accgctctgt tcgccggagg cgatcatgta cagcatcatc
     5641 ggcgggaaca ggcgcaactc cgccagcgcg gcgcgcaggc tgcttccttc gcggacgcga
     5701 tctgccgcca gcagcagttg ttgctcgaca taacgatttg ccgacacggc ggcggcggtc
     5761 tgaatgcctt ccagcagcgg aacactgctg gcggtgagga tgcttaatgt gcgggaaaaa
     5821 cgcgccgtat tcagtccgcg cgcaacacgc cccgtcacgg gcaaacgcag caaggtttta
     5881 tcccagcgca ggcgcatcgc aggatttttg agtagccgtt gccccagcac cagaagcccc
     5941 agcaaacccg ccagccagta cacgccgctg gtctgtaacg tgtcgctcat ggcgatgagc
     6001 attcgggtgg aggcaggcag cgcgtgtccg agatgatcaa actgttcgat aattttcggc
     6061 actactgccg tcagcaaaat agtgaccacg cccgttgcca ccaccagcag taccagcggg
     6121 tagagcatgg cctgcagcag gcgtgatttc agatgctgcc gctgttcggt gtaatccgcc
     6181 aggcgattga gcaccacgtc gagatgtccg gatttttctc cggcagcgac catcgaacaa
     6241 aacagggagt caaagacgcg gggatgttcg cgcaggctgt ccgacagggt ataaccttcc
     6301 tgaatccggc tgcgcagcgc cattccgagg ctttttacat gcagtttttc actttgctca
     6361 ctgaccgcct gtaagcaggt ttccagcggc attgctgcct gcaccagcgt tgccagttgg
     6421 cgtgtgaaca gcgccaaatc tgccgccgcc acgcgacgat gtgcatgccg ccgacgctgc
     6481 aacattcccc ctgtcgaagc attcagccgg gcttcaatgt gcacggggat aagctcttta
     6541 ccacgcaaca attgacgggc atgacgcgcg gaatccgcct caatcattcc tttggttttg
     6601 cgaccattac gctccagcgc ctgatagtaa aacagtgcca ttacgcctcc atggttaccc
     6661 gcagaacttc atcgagagag gtttctccgg cgagcacttt ctcaatgccg ttgctgcgga
     6721 tacccgcaga gtgttgccgg acataacgtt ccagctccag ttccccggcc tgacggtgga
     6781 tcaaatcacg taatgtggcg tccaccacga tcagctcatg gatggcagta cgtccgcgaa
     6841 aacctttgtg attacaggcg ggacagccct gcggatggta cagcgtgacg gttcgcgcat
     6901 cggtaatccc cagcaggcgt ttttcttcgt cggtggcagg cgcggactgg cggcaatcgg
     6961 gacacagcgt gcgaaccagt cgctgcgcca tcacgcccgt cagactggaa gagagcagga
     7021 aaggctcaac gcccatatcc tgcaaacgcg tgatcgcccc caccgccgtg ttggtatgca
     7081 gcgtggaaag taccaggtgt ccggtcagtg aagcctgaac agcgatttct gcggtttcgg
     7141 tatcgcggat ttcaccgacc atcaccacat ccgggtcctg acgcaaaatc gcgcgcaggc
     7201 cacgggcgaa ggtcatgccg acgcgggtgt taacctgcgt ctgaccgatc ccttcaatca
     7261 tgtattcgat agggtcttca accgtgagaa tgttacgcga gtggttgttc agctcctgca
     7321 atccagcgta cagcgtggtg cttttgccgg aaccggtcgg ccccgtcacc agaaaaatgc
     7381 cgtgcggttt gtgtaacagc tggcgcaact gcgcagtcag ttcgagactt aaacccagac
     7441 gctccagcgt caggcgagcc tggtttttgt ccagcagtcg cagcaccacc cgttcccccc
     7501 aggcggaagg catggtggag acacgcacgt caatcgcccg accgcccagc agcagcgcaa
     7561 tgcgcccatc ctgcggtacg cgtttttcgg cgatatccag ccgtgccatc accttaatac
     7621 gcgataccag cagcgaggcc agtttgcgcc ccggacgcag catttcatgt agtgtgccgt
     7681 caacacgaaa acggatcacc agactctttt caaacgtctc gatgtggata tccgaagcgc
     7741 cttctttaat cgcctctgcc aacatggcgt tgatcagttt gatgattggc gcatcgtcgt
     7801 cactttccag cagatcttcc gtttccggta gttcttctgc gagagtaaaa aagtcctcag
     7861 cagaaccgag atcttccatc agctggcggg cctcggaaga gtcccgctgc cagaccgcat
     7921 tcagccgctg ttcaaattcg gcctcgtcga tttgcctcag cgtaaaagac gcgttcagcc
     7981 cccgctgcag ctcctgcaaa acagagagcg acaacggatg aacatggagg atctccagcg
     8041 acgcttcgca ccatgccacc aggctaaacc gacggctgaa actgtagggc agacgcacgg
     8101 tgttagcggt ggtttcctgt gctacaggca ccattaacgc gttctcccgg cattaaggaa
     8161 cgcgcgaact tctggcggta gagcctgatt ttgcgctggc agtaccggct gcgcggtgtg
     8221 cggcatcagg ctcaagcctt gctcatcgcg atagatctgt tcggcgcgca tatagttata
     8281 tttgcgctgc gacacgccgt ctgccgccat accgtcacgc agaatggtcg ggcggataaa
     8341 taccatcagg ttacgttttt cttttttatc cgccgtcgat ttaaacaggt taccaatcaa
     8401 tgggatatcg ccaagcagcg gcactttcgc cacgctttct cccgcctgat cgtccatcag
     8461 accgccaagc acgatcagct caccatcgtt tgccagcacg gtggttttca gtttgcgctc
     8521 gccaaacacg acgtcgagac tggtctgtcc ttccaccttc gacacttcct gctcaatcac
     8581 catctgtacc gcgtttcctt cgttaatctg cggcgtgact ttcagcatga tgccgacttt
     8641 tttcctctct accgtattga aaggattgct gttattagag ccaacagtag agccggttaa
     8701 taccggaacg tcctggccca ccatgaagaa ggcttcctgg ttgtccagcg tggtgatact
     8761 cggcgtggag agcacgttcg agctggagtc gtttttgacc gcctgtacca gcgccatcca
     8821 gtcgcctttc accacgccaa ccgccgtacc gctaaagcca gaaagaagct gagcgagcgt
     8881 ggagagatcg ccgttagtat ccgggttaat ggtggtagcg ccgttttcac tgatcaccgt
     8941 ggagcctttc tgcggttttg cctgagaaat ggctgcaccc agcgtgccaa tagggatctg
     9001 cgtaccgtta gcaaactgca ttaatccggc atctttcgac gcccactgca cgccgaaatt
     9061 gatattgcta ccttcggcaa cttccacgat caacgcctcg acgtgcacct gagcacggcg
     9121 aatatccagt tgttcaatca cgctttgcag cgactgcatg atgtcctgcg gcgcggtaac
     9181 aatcagggca ttactgtgtt tgctggcggc gatggagaca acctcacgcc cgctaccgac
     9241 ggtgccttcc gcctcttctt tagccgccgt gagcgtgccg ctgacctgct tcagtacatc
     9301 gaccagatct tcggctttgc tgtatttgag atagaaaacc tggctgttgc cgctgcgttc
     9361 catttctgag tccagccgac ggatcaggcg gcgcattttg tcccgcgtgg ccgggtcacc
     9421 actgacaatc acactgttgg tgcgttcgtc ggcgacaatt tgagatttca gcgtcgcagg
     9481 ctggttctcg ccgctgtttt tcgtcaggct ttccagcacg cgggcgattt ccgaagccga
     9541 ggcgttatcc agcgggatca cctcttcggt gcgattaccc gcatgatcca cgcgctggat
     9601 cacttccgtc aggcgctcca caactgaggc gcgtccggta agcataatca cgttggaggg
     9661 atcgtaatta acaacgttgc ctgagcctgc gctgtcgatc atctggcgca gaatcggtgc
     9721 cagctcgcgt accgacacat tacgtaccgg cacgactttg gtgaccattt catcgcccgc
     9781 gtagttgtcg ctgccttcac caaccagcgg cagcggctcg actttcgcgg cactggattt
     9841 caccaccttc agcacgtcgt tttccatcgg tacgacggca tacccctgtg cttccagcag
     9901 gttaaggaat agctggtaat actggcgttc attgagcggg gtcatggtgc gaatactcac
     9961 tttcccctga acgcccggcc ccataatgat ggttttatta aggttagcgc cgacggtttc
    10021 gatgaacgat ttcaggtcgg tatctttaaa attagcggtg aaagtggctt cttccgccca
    10081 gaccggtgaa ctgcataatg ccgctgccag caccagcgcc agtaaacgct tttttgtttt
    10141 gaggccagtt gtcttcttac gccagaccga caacgtcata tcacgccaaa acacgatgaa
    10201 tgattctcct ggattaaatg cggttagcgc agcgcgatgg aaatgtcgta gcgcgcaccc
    10261 ttgcgtaaaa ccgtaagttg aatggaatcc attgaaggta actgccgcat cagagcaatc
    10321 attgctcgtg gatcagtgaa atcctgctga tttagcgcaa tggcgatatc gccttcctta
    10381 aaaccgctgg catcgaacag agaacgatct gcccccggtt tcactgcata accgacaatc
    10441 ccttccttac gcacaggcgt aagctggata tagttaaaaa ttttctgcgg atctttcgcc
    10501 agtgcctgac gcacggcagc cgggatctca actggcgcac tggcagcagg ctcagcaaca
    10561 gcttgctttg cttcgtcgct gacggctttt ttgctggtca cggctttggt gggacgcttc
    10621 tcttctgcca gactcagacg ttccattttc ccctgatagc gcagcatcac atggtcacga
    10681 ttaatttcct caatcaccgc gttgtgagag ccaagccgtt cgccctgtaa atagacctgc
    10741 tgtttgccgc cttctttaat caccgcgccg ggtctggcac caaaggcgat cccgcgcagc
    10801 accacattaa gacgcgtttc tgccacaggc gcaggttcgg gttgttttac cggtgcggcg
    10861 acgggttgat atttgccaaa ccagttttgt tggctgacta attgcacgtc atttttatcg
    10921 aacggttttg catccgcacg gagcggttta ttcgccgatg aggaaaccgc cgtatattcc
    10981 gcagaaaagg agaaatagcg ccagagtgaa tacgccattt ttgcagaaat aataagcagc
    11041 atgagccaga acatcccgcg caccattttt cgcagatgct ctttgtctgt attaagagat
    11101 tgtctctggc taagagtgtg acgaattttt gtcagcaact gaatgagata aattcgtgcg
    11161 tcacgaaaaa caacccgcgc caatttatat ctacccgacg ttatgctttg actattccac
    11221 aggtggtacg atccagtttc cgctgatact ggtttcctgt acgtgtatca ttaatcgtta
    11281 tgctgtaatt aattccctcg gtaatcatta atttcaccgt cgggtcagcg cacatttgtc
    11341 gttgatagct ggttaaaaag gcatcaggtg tctgcgtggt ctgagcaccc gcttcgctga
    11401 taatggtcat ttttaccgtc gtgccgctac tttgcgccag cactaaggta tatcccgcag
    11461 atttaatcgg caggttttgg ctgatatttt gcgcctgttt tttcgccagt aaactggcat
    11521 tttcattatg gccggcacag ccacttaata atcctgtaac gctcaacaat agcgatatta
    11581 ataccctccc tggcatttgt tttatcgaca tggtaaataa tctctaaggt tattaataag
    11641 agttaaaatg tcactttgat aatgacgtgg ttatcattaa aacaatgcct gtagataaag
    11701 tgttgctata ccgcccagac ttaaacacgg tccaaaaggc agtgtggttg atcctctttt
    11761 tgtaataacg gcatatatca ggccgcagca tgatgcgatt aaagcaacat tgggtagcga
    11821 caacggcccc acccagccac ctaacgcagc gaaaagtaat acatcgccca tgcctaatgc
    11881 ttctttacgc agaactattc cggctatcca gcgcagggag taaaaagtga taaaccccac
    11941 caggacgccg gtaactgcgt cttgtagcgt taacggactc tgttgcgccc atgccgcaat
    12001 cagcccggtc cacaatacgc cctgagtaaa aacatcgggc agccattggt tatcgaggtc
    12061 aatgacgctc gcggcaatca gccaggcgga taatatcatc accgccagcc cccatccact
    12121 ttctggccac accagactcg ccagcaaaaa agcgagtgcc gtcaataact ccaccagcgg
    12181 ataacgcttg ctgattttcg cctgacagtc gcggcagcgc cctttgagca tcaaccatga
    12241 gagcagcgga atattgtcac gaacgcggat ggtctgctgg caatgcggac agtgcgagcg
    12301 tggcagcgcc aggtttattt ttgactgcgt actcggcatt tcaccgtgaa actccgccat
    12361 ttgttggcgc agcatgatgg ggtaacgcca aatcaccaca ttcaaaaaac tgccgatgat
    12421 caatcctccg acggttgcca gtatgggcat ccccgcggag tattgctgaa aaacatcaaa
    12481 aagcatggtt aaaggttgtt tgttgtaact tgccggatgc gggcctgcgg gtgtatgcca
    12541 tatggctttc ctccaggccc gatgcgcctt atttcatgcc ggatgcggcg cgagcgcctt
    12601 atccggcata caggcttact cagctgacat cttatgctcg gtaacctgat taatggtttc
    12661 cggcccttgc tgcggtttcg gcagattaag cgccgccagc gtctcgtaag ccgactggct
    12721 cacaccgccc tcgaagttca tctcgctcgc tcccggtaac tggtaagcat tcgcgcccgg
    12781 attccatttc ttaaagaact ccgaaagatc cgtctgagcg acccaggagg cacacagcat
    12841 cagcttgtcg gcagcgttac cgttggattc ggcacagtaa tttctttcgc caaacttggt
    12901 tttgccaaca tcatcgccgc gtgctttacg gtgcatcaac tggaacaggt tccagccttt
    12961 catcccttca cgatcgctgt agaactcagg caggtcacct tctggatacc actgtttgat
    13021 atcaaagttt ttctctgccc actccttcag ctgcgcgtac atcagcagac ggtcgcccgc
    13081 accgccgcgc gcccatgcct gaccgttgct ctcctccaga tattccggcg cgacagtaat
    13141 atcgtcagcg acacggttca tcttgccgag atagcgatcc tgcatgtaca gcgccagaac
    13201 gttgttcgct acttcagttg cgccaggaac agtcagcggc gtttcggcgg cgttgtgccc
    13261 tacttcgtgc cagatcaacc agtcgttcag cggcgtcgtc ggcagcgtgg tgctgttcgt
    13321 cgagaagctg ctgttcatta ccggataacc cgagtgcgca tcaccgatgg agatctgcac
    13381 atcgttggtg aaacgatgct tgtgccccgt caagttttta taggtaaaca tccggtgctt
    13441 accgtcttca tcattacgac cgtagaagtc attcatcgag ctggcaaagg tatccagatc
    13501 tttagcgaat tctgctacac caccagtgaa attgctggcc tcaaggttct tcttcggcgt
    13561 ggtataaacg aaagcgtctg attccagctc gcccagcggc gcaggggagt tcagagcgtt
    13621 tttccattcg ccgtctttat agaacggcgc ttttaccaca ccagtaaagg tgaattcggc
    13681 tgactcattc tttgggctgt tgcccttgat ataaatcaga ccaccgtaag gcaccttgaa
    13741 ggtcacctta tcattggctt tcagatcata ggttttcgtc acttttggcg gacggttcag
    13801 cgcgacttca tgcttctcgc gtccggtcag atcgtcggcc agcgccacgg tgacagtcac
    13861 aggaactgat gcagaagact caatggtgac ctctttctga gccggagccc acaggccagt
    13921 agactgcatg ttacccgcaa accatttggt cggattggag tacaggctga tggtttcagt
    13981 aaccttctca ccttctgccg ataccgctcc cggatacttc tcgacatcaa ctttgatgtt
    14041 cagatcccac caggaacgac ccagcatcag gcgcgtcagc ggtttttcca tatagttgag
    14101 cggatagctc gggttcatca tgcccgcttt attaacgctc ttctcgccgt agatcatgtt
    14161 gttatcgacc agcgattttt tcagctcatc agaacactgc gtgccgccag tataggcatc
    14221 gttggcgtag cagttcagga actcggtgaa cgttttaaag cccagctcgt catccttgtc
    14281 gttttcatag cgatattcaa ttttattcca cagccagacc gacacgttct ggtacagacg
    14341 ttccagatcg acgctgctca gacgctcacc tttgcgacca ttggtccgga agtagagctc
    14401 atgctgatac agacgctgaa tgttggtgcc taaatccgca gcctgcacca tcgcttttgc
    14461 cgtgtcggcg ttaaggctta gttgcgtata ctgtggaaca tacatgccac cagtaaccgg
    14521 aacccccgtg ccaggacgat attccagaca gttgacctcg tagtggtaag ttgggtcctt
    14581 acactccttt aatccaggaa acttctcaaa gatttttgcc ttcgcagcct tcagagaatc
    14641 ctctgtttta tgatcggcct catcaataaa ggcataacgc gtttcctgtt tgccatctac
    14701 atcttccagc cagctggcaa cttccagctt cggtttgtca tcaggtttgt tttctacctg
    14761 atatttccac ttaacttccc ctgtcttact atcgatggtg tacggcagcg caccatctac
    14821 ggcaggataa cgttcataga cccaaatgcc cgttgcgcgc tgctgacgaa cgcggttcgg
    14881 atacccttgc ggatcgttat ttactaccga cttgttcagt gccatcgaca gacctgcggc
    14941 atcaagcaga cgtacaaagc cagacgcgct ctcttcctta agattgctca tcacgttttc
    15001 catgatcagc accgatccac ctttgttcag ataggcgatc agatcggtca catcctgctg
    15061 agtcagcttc ggtttgctgg tatctgctcg cagcgggatt gcataaggat cgttaccaac
    15121 ctgagtcaca tactcaaagc cgttgaggat cagcagcggc atttcctgcg ggtcgagatc
    15181 gccatagcta cttaaatgct caacagagat acccgcaaaa tccggatgaa agccgaactc
    15241 agcgctgttt cctgtaacct gaccatgacg tttgaaatag acagtatcca ggttggtgcc
    15301 tacggtcatg ctggctttcg cgtccggcgt ccatttatcg tcggacagat agcgcaacac
    15361 gttctgcata aagtgcttca tatcattaga atcactgtta cgcgtacact gaccgttttt
    15421 atcaacaccg ccttcccagc tgtaaccgtt cggacaacgc aaaatgctgt tgtagtgcgg
    15481 gttaccgata accatcagtt tgccctcacc gacttgcccc agcgaaataa acggcaggtt
    15541 aaaggtggcg gtatcgcgcg taacgttttc cggctcaacg agagaaggcg cttccgtaat
    15601 gtacgccagc tcgtttttat cccaggcgcg tttttcgcca aacgccagcc agtagttttt
    15661 atcattacgc gccatcagaa tcgggaaggc cgcgttggag atattcacca ctgcctgacc
    15721 gcgcgcatta ccggtactgc catagaagtt ggtagagtca tggaagacgt ggaatttcgt
    15781 cactgatttg taatctttat ccacacccca cagcttgttg ataacgccct gaatctgacc
    15841 ttcgttaaca ttgcgtgctg tcaacgagaa ccaacgctga gagttgcagc ccccaaggga
    15901 gtcacaaatc gccgtatcaa tctctttagc ctgcccggat tcaaactgct caagaaattc
    15961 gtttgtccgc tcaaaggttt gatcaccttc gctcaacgcc tcgccattgg ataacgagag
    16021 attgataatc tcgttgatta cgttgggata ctcggcaaag accttgcgca ctacgtccgg
    16081 cacttcacgc tcatcatttt ttccggcctg ggagtaacga tgaataagct gatcaatatt
    16141 cgcgccgcga acttcgtcac ccagttcagt caacgcaatg gtcgacttat tgccgcgcac
    16201 tgagcccagt tcaaaggtgt cgataccaaa ggagatggtt tcgccccagc tgaagttgaa
    16261 tttgccgttt tcgccagtta cgccacggcc tgagctggtg tagtaattta cgccaaccac
    16321 accattgccc atgctatcta ccagtcggcc ttcggagaga atgatttcag tgggttgata
    16381 ctgataaaac tgttccgcgt tagccgacac gaaggaagcg ttcagatccg gttttgttcc
    16441 cggcgtggtg acgggcacaa ccggtgaagt atgagtggat ggcgctttat cggtcgcggc
    16501 attgttttcc acctcttcat tgaccagctt tttgaactct tccggtgcca gatcgatttg
    16561 cttatacagc gagtcgaaac gtttactctc gatcactgag gagaacgtca ggcaaacctg
    16621 ttctgtattc gccggacagc tgttactgga cgttaccagc gaaaccgcat tgcttttctt
    16681 gtcatcggaa gctgccagtt cttgcgcgtc ctcaagacta aacgacactt tttcaaccgc
    16741 acgcaggcta cgcgcagctt ctgactgggt gtcgaaggta gcaattgtcg tgttacccgc
    16801 cacgcaagta acgtcctcac caggtgtaaa tgtaaagcca tcgctggatt caccattaca
    16861 agtagcacca gttacccgct ggcttccgcc cagggtcaga taacccgttt tcgtaggaac
    16921 aggttctggc tccggttctg gctcaggatc aggtgtcggt tccggcgtag gttctgggtc
    16981 cggcgttggc tcaggcgtcg gctccgggtt tggtgttgga tcaggtttca cttccggcaa
    17041 agaccctgtt ccagaatcta caggcggcgt atcggaggaa gatccggagc caccgccatc
    17101 acaaccggct aacagggttg cactcaaaat agccgctaaa agcgatttct tatatttaaa
    17161 tttcttattc attaataacg caagtgacaa aacaaagtta aaagattcgt aaccggggaa
    17221 atagttttat gcttta
//
LOCUS       DAPOXO010000100        17233 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPOXO010000100 DAPOXO010000000
VERSION     DAPOXO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17233
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.100"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            254..532
                     /locus_tag="ROH59_004180"
                     /pseudo
     CDS             254..532
                     /locus_tag="ROH59_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(583..828)
                     /locus_tag="ROH59_004181"
                     /pseudo
     CDS             complement(583..828)
                     /locus_tag="ROH59_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            complement(1201..1431)
                     /locus_tag="ROH59_004182"
                     /pseudo
     CDS             complement(1201..1431)
                     /locus_tag="ROH59_004182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546148.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            2018..2173
                     /locus_tag="ROH59_004183"
                     /pseudo
     CDS             2018..2173
                     /locus_tag="ROH59_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608786.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
     gene            complement(2170..2616)
                     /locus_tag="ROH59_004184"
                     /pseudo
     CDS             complement(2170..2616)
                     /locus_tag="ROH59_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001218945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
     gene            complement(2803..2887)
                     /locus_tag="ROH59_004185"
     tRNA            complement(2803..2887)
                     /locus_tag="ROH59_004185"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2851..2853),aa:Leu,seq:caa)
     gene            3083..4102
                     /gene="ahr"
                     /locus_tag="ROH59_004186"
     CDS             3083..4102
                     /gene="ahr"
                     /locus_tag="ROH59_004186"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HDX4806596.1"
                     /translation="MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVI
                     LKADF"
     gene            4232..5734
                     /locus_tag="ROH59_004187"
     CDS             4232..5734
                     /locus_tag="ROH59_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HDX4806597.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIGVNDWQPHANPVVVWDIFG
                     EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLDIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRTFTPKDQKAV
                     KAAAQTMRVNPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPMTE
                     DERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASAEQQNNPAVKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR"
     gene            complement(5895..6977)
                     /gene="lptG"
                     /locus_tag="ROH59_004188"
     CDS             complement(5895..6977)
                     /gene="lptG"
                     /locus_tag="ROH59_004188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDX4806598.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQIDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(6977..8077)
                     /gene="lptF"
                     /locus_tag="ROH59_004189"
     CDS             complement(6977..8077)
                     /gene="lptF"
                     /locus_tag="ROH59_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDX4806599.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVTDSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            8344..9855
                     /gene="pepA"
                     /locus_tag="ROH59_004190"
     CDS             8344..9855
                     /gene="pepA"
                     /locus_tag="ROH59_004190"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDX4806600.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            10211..10654
                     /gene="holC"
                     /locus_tag="ROH59_004191"
     CDS             10211..10654
                     /gene="holC"
                     /locus_tag="ROH59_004191"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HDX4806601.1"
                     /translation="MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            10654..13509
                     /gene="valS"
                     /locus_tag="ROH59_004192"
     CDS             10654..13509
                     /gene="valS"
                     /locus_tag="ROH59_004192"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDX4806602.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(13563..14759)
                     /locus_tag="ROH59_004193"
     CDS             complement(13563..14759)
                     /locus_tag="ROH59_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709944.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 domain-containing protein"
                     /protein_id="HDX4806603.1"
                     /translation="MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLP
                     WALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFFYFAILMTVSADMPLVDCV
                     LTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSLKGFWWVTFFLPILMAIGMGTV
                     FFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFK
                     VKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQ
                     RKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCAL
                     VVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIM
                     PSLPFL"
     gene            14952..15455
                     /locus_tag="ROH59_004194"
     CDS             14952..15455
                     /locus_tag="ROH59_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX4806604.1"
                     /translation="MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGK
                     GLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCE
                     VRMLREL"
     gene            complement(15501..15917)
                     /gene="rraB"
                     /locus_tag="ROH59_004195"
     CDS             complement(15501..15917)
                     /gene="rraB"
                     /locus_tag="ROH59_004195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HDX4806605.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH"
     gene            16079..17083
                     /gene="argF"
                     /locus_tag="ROH59_004196"
     CDS             16079..17083
                     /gene="argF"
                     /locus_tag="ROH59_004196"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDX4806606.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNTLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKTFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNNKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
                     "
BASE COUNT         4370 a         4364 c         4461 g         4038 t
ORIGIN      
        1 ttgatggtag ctaacttagt aattatataa aaaactttta caatatccga gagtatgtat
       61 gcataatgta tgcgcccccc tatcaggctg tctcttatac acaaatcccc acccggggat
      121 ttgtgatgtc tgtcagtctg ctttaggggg gactctttcc attcggtagt ttccttcctc
      181 cccggcagcg attttttgaa ctttttcttc acccgttgat cttctcttat atttcatttt
      241 cttcgggtct gttatggtac tttctgattg ttattcatgg gataacgagc agtttggaca
      301 tgcccgtctc ggtgatccgc gtcgtacacg acgccttgtg tcactggcct cttctctcgc
      361 tcagcatgca ggtctttcta ttgtgaaatc atcccactcc actgctcagg ttgaaagtgc
      421 gtaccgcctg atacgtaacc cgtctgtgtc cccggaagcc attgcctaag ccggatttac
      481 cgccactgca agggcatgtg aggctcatcc gctgctcctc gcactggaag acaccaccac
      541 taatcgtaag cgtacagcga gggccgtatt gacggggatg tgttattcag ctggcagtgc
      601 tatacgccac ggaagcagtt cgctgacccg gttgaccggc cagtctgcta tgacgccaag
      661 cacatggcga aggtagcttt ctggatccac gtcattcagt ttgcacgtcc cgatcaggct
      721 gtacagtagc gctccccgct caccaccatg gtcagagccg aagaacagga agtttttacg
      781 acccagactg accgtcaacg ccacaatctt tgactgtttg acattgtcat gcccgcaggc
      841 cagcgaatct aaagacatca gactgcttgc atcagccagt tgcgtatctg gctatgtccc
      901 ttaattggta agggttcgag gaactcaaca ttaacgcatt tttccgccca tcaccggcag
      961 tgtatatgaa cgattgcact cttacgatgg ttgatttatt tggttgcgta ggggctagct
     1021 agtctggtac cggaggctgg atctgaagta ctgaccccaa gaataacgcc gggcagactc
     1081 atattctgac ccattgtcag cccgcgtgtt tactgctcta gctcatttcc tgttgtcagg
     1141 cgttcaattc ccaactgcag gttatggccc ggtgcacaaa cacctgacgg caggtatcac
     1201 ttacccaaag aagataaagc cctcaagagg cagtaactct gccaacctct cctccggcca
     1261 ctccgggcag acgcgttagg acgtccgtca gccaagcatg tggctccaga ctgctgtttc
     1321 cagaaggctc attatctgtg ccgctcggtt cccggccatc agtgaaccag cgaacaacca
     1381 ggcctttcgt cccataacga ccggacggat agcacgctcg cagatattgt tgtgtgtgcc
     1441 ttgaaatgca cgatctttcc gtcggtgaaa gtccgccccg actaactctc gctccaactg
     1501 gaaggacagg aagcggtcca ggaggtaaca aaagggctga atctctccct gaaacgactt
     1561 cttcaggaag tcaatgggtt atgcgggccg taacgtgagt gaacactgag cagccatcga
     1621 aatgccgtcg atggtgccga tacgccacaa taacggggaa ggccgacgat gaccgggaag
     1681 agagtgagaa aggcatcggt catacccacc ggggtagtgg tgtcagcatg cataacaatt
     1741 gatcgatcgt gcaacaagag aagtccataa cgatgcctgt ccgggtgacg ggcaacaacg
     1801 cctcccgagg gggtgaatcg gttgttatgg atggcagatg gggtgtagta gtgaaaatac
     1861 tgagtaatgt cataggagcg aaggccccct gttgcagtac cagtgtaaca tgcaggaaga
     1921 gcccggggat tgccatcagc ctcacaaccc cgctcgaacc ggttcagaac ctacagaaaa
     1981 tactacagga gaaagcaaag tgaacctccc cgtgtttcct gtttatcatt ttctggtcag
     2041 tgccgcgatt ctggtattcg tggtgatttt ctggcggaca caccatcgcg accaccgtaa
     2101 ctggctggct ctacggctat tcgtattatg ctctgtaaac cgttggccat tgcggatggt
     2161 taaaggaaca ataggtgcta ataaatctcg agtttttaac tcagcgatat tacgttcacc
     2221 aagcgctgca aaaagattat cttcaagact ttttagcaca cgatgggcgt gatcttcaga
     2281 ccacttttta ttggtgccat gccactcaat cgcgacttct ttaaaggttc gtgctttact
     2341 ctgttcaacc ttatcatttt tctttttgtc tcccggatcg acgccattcg caagcagctt
     2401 acgcgcctcg tcacgacgta ctctggcatc cgctagtgtg atttcaggat aaaccccaag
     2461 tgccagcatt ttttgctttc cctcataacg gtactgcaaa cgccagtact tagaaccatt
     2521 tggatggaca agcagatgca taccgccacc atcagtcagc ttatattgct tatccgttgg
     2581 cttggctgct ctgactttga tatctgttaa tgccatgcgt attccctccc tgttggtaca
     2641 agcattatcg aaccggaaat accatcatct gtaccaacat atgttggtag atgtacgttg
     2701 atatcggttg accttgagag agttaatata gcgggaaaga tagataaaca ctggatttca
     2761 ggcataaaaa aagacctcag ttgaggtcta tttacatact tttggtgccg aaggccggac
     2821 tcgaaccggc acgtatttct acggttgatt ttgaatcaac tgcgtctacc gatttcgcca
     2881 cttcggcact gaagaggtat gcggaaaacg ttgtggatta tacctgtcgc acgccaccat
     2941 gcaagcgcca gcttgctcgc acctcgctaa gtgctgaaat tttcagcatt gcatacagcg
     3001 atgtgtaacc tttgtcacac tccaggcacc ccgccctgcc atgctctaca cttcccagac
     3061 aacaccagag aaggaccaaa aaatgtcgat gataaaaagc tatgccgcaa aagaagcagg
     3121 cggcgaactg gaagtttatg agtacgatcc cggtgaactg aagccacaag atgttgaagt
     3181 gcaggtggat tactgcggga tctgccattc cgatctgtcg atgatcgata acgaatgggg
     3241 attttcacaa tatccgctgg ttgccgggca tgaggtgatt ggtcgcgtgg tggcgctcgg
     3301 gagcgccgcg caggataaag gtttgcaggt cggtcagcgt gtcgggattg gctggacggc
     3361 gcgtagctgc gggcattgcg atgcctgtat tagcggtaat cagatcaact gtgagcaagg
     3421 tgcggtgccg acgattatga atcgcggtgg ctttgccgag aagttgcgtg cggactggca
     3481 atgggtgatt ccactgccag aaaatattga tatcgagtcc gccgggccgc tgttgtgcgg
     3541 tggtatcacg gtcttcaaac cactgttaat gcaccatatc actgccacca gccgcgttgg
     3601 ggtaattggt attggcgggc tggggcatat cgctataaaa cttctgcacg caatgggatg
     3661 cgaggtgaca gcctttagtt cgaatccggc gaaagagcag gaagtactgg cgatgggtgc
     3721 cgataaagtg gtgaatagcc gcgatccgca ggcactgaaa gcactggcgg ggcagtttga
     3781 tctcattatc aacaccgtca acgtcagcct cgactggcag ccttattttg aagcgctgac
     3841 gtacggcggt aatttccata cggtcggtgc ggttctcacg ccgctgtctg ttccggcctt
     3901 tacgttaatt gcgggcgacc gcagcgtctc tggttctgct accggcacgc cttatgagtt
     3961 gcgtaagctg atgcgctttg ccgcccgcag caaggttgcg ccgactaccg aattgttccc
     4021 gatgtcgaaa attaacgacg ccattcagca tgtacgcgat ggtaaagcgc gctaccgagt
     4081 gatcctgaaa gccgacttct gatccctttg ccgggtgcct gtcgcccggc acttaaatct
     4141 ctttggaagg cgtctcgcaa tctgctgaat ttagcggtga agagtgcgca gccgttgcct
     4201 atactccagg caggaaactg gaggaaatct catgagcgaa cccctgttaa ttgcccgcac
     4261 gccggacaca gaactatttt tactgccggg aatggctaac cgtcacgggc tgattactgg
     4321 cgcaacgggg acgggtaaaa ctgtcacgct gcaaaaactg gcggagtctc tatcggaaat
     4381 cggtgttccg gtgtttatgg ccgatgtgaa aggcgatctg accggcatcg cgcaggcagg
     4441 aacggcgtcg gaaaaactgc tcgcaaggct taaaaatatc ggcgtcaatg actggcaacc
     4501 gcatgccaat ccggtggtgg tgtgggatat ctttggcgag aaaggccatc cggtgcgggc
     4561 gacggtttcg gatctggggc cgctgttgtt ggcgcggctg ttgaatctca acgatgtgca
     4621 gtctggcgtg ctggatatca tcttccgcat tgctgacgat caggggctgt tactgctcga
     4681 ctttaaagat ttgcgggcga ttacccagta catcggcgat aacgccaaat ctttccagaa
     4741 tcagtacgga aatatcagta gcgcatcggt tggtgccatc cagcgcgggc tgttgtcgct
     4801 ggaacagcaa ggcgcagcac acttctttgg tgagccgatg ctggatatca aagactggat
     4861 gcgcaccgat gccaacggta aaggcgttat caatatcctc agcgccgaga agctttatca
     4921 gatgccgaaa ctgtatgccg ccagcctgtt gtggatgctc tcggagttgt atgaacaatt
     4981 gccggaagcg ggcgatctgg agaaaccaaa actggtgttt ttcttcgacg aggcacatct
     5041 gctgtttaac gatgcaccgc aggtactgct ggataagatt gagcaggtga taaggcttat
     5101 tcgctcaaaa ggcgtgggcg tctggttcgt ttcgcaaaat ccgtccgata ttccggataa
     5161 cgtgctcggc cagctcggta atcgcgttca acacgctttg cggactttta cgcccaaaga
     5221 tcagaaagcg gtaaaagctg cggcgcaaac catgcgggtc aatccggcat ttgataccga
     5281 aaaggcgatt caggaactgg gcaccggcga ggcgttgatc tcttttctgg atgcgaaagg
     5341 aagcccttct gtggtggaac gggcgatggt gattgcgcct tgttcgcgga tgggaccgat
     5401 gacggaagat gagcgtaatg gcttgattaa tcactctccg gtgtatggca agtacgagga
     5461 tgacgtggac cgggaatccg cctatgagat gttgcaaaaa ggcgtacagg caagcgccga
     5521 gcagcaaaat aatcctgccg tgaaagggaa agaggtggcg gtggatgacg gcattcttgg
     5581 tggattgaag gatattttgt ttggcactac cggaccacgc ggcgggaaga aagatggtgt
     5641 ggtgcaaaca atggcgaaaa gcgccgcccg ccaggtgacg aatcagattg tacgtgggat
     5701 gttggggagt ttgctggggg gaagaagaag gtaagtcagg cgcgatttgt ctttgcctga
     5761 tgcgacgctg gcgcgtctta tcatgcctac accactgcaa tatattggat tttcatgatt
     5821 tttcaggcat gaacgaagca cactttgcta acaataataa agggagcttt cgctcccttt
     5881 attcgttcat tcggttacga ttttctcatt aacagccaca ggctgattaa gaagaagctg
     5941 gcgcttggca acagtgcgcc gatgatcggc gggatgccat aaaccaacgt cagcgggccg
     6001 aagatctggt ccagtacata gaagacaaaa ccgaagctga taccggtgac cacacgcaca
     6061 cccatcggta cgctacgcag tgggccaaag atgaacgaca gcgccatcag catcatcacc
     6121 gccacggata gcggctggaa gattttgctc cacatgttga gctgataacg tccggcatcc
     6181 tgaccgctcg atttcagata cttcacatag ttgtgcaaac cgctgataga gagtgcatcc
     6241 ggatccagcg ccaccacgcc cagtttgtca ggcgtgaggt tggttttcca ggtgccgctc
     6301 accgtctgcg aaccggtgat ctgtttcgga ttggtcagat cagattcatc aatctgcgac
     6361 agacgccaga ctttatgttc cgggtcaaac ttcgcggtag cggcatagcg tacggattgc
     6421 agacgacgat tctcgttaaa ggcataaata ctgatgccac ctaactcttc gtcaccttta
     6481 acccgctcaa tgtagacgaa gttgttgcca tctttcgccc ataaaccttg ctgggtagag
     6541 agcaacgagc cgccgtacat cgcctgcgca cggtagttac gcgccatctg ctcgccctgc
     6601 ggcgcgaccc attcgccaat cgccatcgtc agcaagacca gcggaatggc ggttttcatc
     6661 accgacagcg ccacctgcat acgggtaaaa ccagaagcct gcatcaccac cagttcgctg
     6721 cgctgcgcca gcatcccaag accaagcaac gccccaagca aagccgccat cgggaagaat
     6781 atttgcacat ctttcggcac gctcagcaag gtatacattc ctgcgcctaa cgcgtcgtag
     6841 ctcccctgcc cggctttttt caactgatcg acaaatttga taatgcccga cagcgacacc
     6901 agcatgaaca gcgtcatcat gatggtggtg aaaatagttt taccgatata gcggtcaagt
     6961 acgccaaaag gttgcatcac accgctcctt tacgcgaaaa actggcgcgc aggcggcgga
     7021 ccggcacagt gtcccaaagg ttgagaacaa tcgccaaagc cagataaatc aggttaacgg
     7081 tccacatcca cagcgtcggg tccagcttac ctttaccgcc gttcgatttc agggaggtct
     7141 ggatcaggaa gaaaagtaga tacagcagca tggctggcag catcgacagt acgcgtccct
     7201 gacgcgggtt aaccacgctc aacggtacaa ccataagtgc catcataaac acggtgaata
     7261 ccaacgtgat acgccagttc agttctgcgc gggcacgatc ggtgtcagtg ttccacaatg
     7321 tgcgcatgtc catctggtcg gtatcgttcg ggtcgagcgc caccgcctgg tgaccaatga
     7381 tcgcctgata atcctggaaa tccgtaatgc ggaaatcacg taacagtgca gtgccttcga
     7441 agcgcgttcc ctggttgaga gtgacgacct gggagccgtc gcgcagctgg gttaaatgtc
     7501 cggaatcggt caccaccaca gaaggtcgtg cattaccttt tggtcgaatt tgtgcgagga
     7561 acacatcttt gaaatcgctg ccgtcaacgc tttcgatgaa cagcaccgag ctgccattag
     7621 tcgcttgctg gaattgccct tgcgccagcg ccgccatgcc agggttcgct ttcgcttctg
     7681 ctaacacttc atcctgatga cgcgatgacc acggtcccgc ccacatcacg ttaaccgccg
     7741 cgacgattgc cgtgaatacc gcaaggatca ttgccgcttt caccagaacc gctttgctca
     7801 ggccgcaggc atgcattacc gtaatttcac tttcggtata cagtttgccc agcgtcatca
     7861 gcagcccgag gaacaggctt aatggcagga taagctgcgc catttccggc acgcccaacc
     7921 cgagaaggga gagcaccaga ttcgccggaa tatcgccgtc aaccgctgcg ccgaggatcc
     7981 tcactaactt ttgacagaag aagatcaaaa gcaagatgaa gagtatcgcc agctggcttt
     8041 tgagcgtctc ccgcaccaga tatcttatga ttatcacttt aaatacgccc gtaaaaactc
     8101 gtcttttgca ggattttagc ttgtttcatg gcttaaacgt catttattct cttgagtcgt
     8161 cgaaatcgtc gctaagataa ttatactcaa cggattcacc tctcagattt tgttctgacg
     8221 tgccaatgcc gtaataacgt taagattaac acgaagtcat cgcaacagcg gacatgagtt
     8281 acgaaagctt gcaattctat ctgtagccac cgccgttgtc tttaagattc aggagcgtag
     8341 tgcatggagt ttagtgtaaa aagcggtagc ccggagaaac agcggagtgc ctgcatcgtc
     8401 gtgggcgtct tcgaaccacg tcgcctttct ccgattgcag aacagctcga taaaatcagc
     8461 gatgggtaca tcagcgccct gctacgtcgg ggcgaactgg aaggaaaacc ggggcagaca
     8521 ttgttgctgc accatgtacc aaacgtgctt tctgaacgca tcctccttat tggttgcggc
     8581 aaagaacgtg agctggatga gcgtcagtac aagcaggtta ttcagaaaac cattaatacg
     8641 ctgaatgata ctggctcaat ggaagcggtc tgctttctga ctgaactgca cgttaaaggc
     8701 cgtaacaact actggaaagt gcgtcaggct gtcgagacgg caaaagagac gctctacagt
     8761 ttcgatcagc tgaaaacgaa caagagcgaa ccgcgtcgtc cgctgcgtaa aatggtgttc
     8821 aacgtgccga cccgccgtga actgaccagc ggtgagcgcg cgatccagca cggtctggcg
     8881 attgccgccg ggattaaagc agcaaaggat cttggcaata tgccgccgaa tatctgtaac
     8941 gccgcttacc tcgcttcaca agcgcgccag ctggctgaca gctacagcaa gaatgttatc
     9001 acccgcgtta tcggcgaaca gcagatgaaa gagctgggga tgcattccta tctggcggtc
     9061 ggtcagggtt cgcaaaacga atcgctgatg tcggtgattg agtacaaagg caacgcgtcg
     9121 gaagatgcac gcccaatcgt gctggtgggt aaaggtttaa ccttcgactc cggcggtatc
     9181 tcgatcaagc cttcagaagg catggatgag atgaagtacg atatgtgcgg tgcggcagcg
     9241 gtttacggtg tgatgcgtat ggtcgcggag ctacaactgc cgattaacgt tatcggcgtg
     9301 ttggcaggct gcgaaaacat gcctggcgga cgagcctatc gtccgggcga tgtgttaacc
     9361 accatgtccg gccaaaccgt tgaagtgctg aatactgacg ctgaaggccg cctggtactg
     9421 tgcgacgtgt taacttacgt tgagcgtttt gagccggaag cggtgattga cgtggcgacg
     9481 ctgaccggtg cctgcgtgat cgcgctgggt catcatatta ctggtctgat ggcgaaccat
     9541 aatccgctgg cccatgaact gattgccgcg tctgaacaat ccggtgaccg cgcatggcgc
     9601 ttaccgctgg gtgacgagta tcaggaacaa ctggagtcca attttgccga tatggcgaac
     9661 attggcggtc gtcctggtgg ggcgattacc gcaggttgct tcctgtcacg ctttacccgt
     9721 aagtacaact gggcgcacct ggatatcgcc ggtaccgcct ggcgttctgg taaagcaaaa
     9781 ggcgcaaccg gtcgcccggt ggcgttgctg gcacagttcc tgttaaaccg cgctgggttt
     9841 aacggcgaag agtaattgcg tcaggcaagg ctgttattgc cggatgcggc gtgaacgcct
     9901 tatccgacct acacagcact gaactcgtag gcctgataag acgcgcaagc gtcgcatcag
     9961 gcaatgctgt tattgtcgga tgcggcatga acgccttatc cgacctacac acagcactga
    10021 actcgtaggc ctgataagac acaacagcgt cgcatcaggc aatgctgtta ttgtcggatg
    10081 cggcgtgagc gccttatccg acctacacac agcactgaac tcgtaggcct gataagacac
    10141 aacagcgtcg catcaggcgc tgcggtgtat acctgatgcg tatttaaatc caccacaaga
    10201 agccccattt atgaaaaacg cgacgttcta ccttctggac aatgacacca ccgtcgatgg
    10261 cttaagcgcc gttgagcaac tggtgtgtga aattgccgca gaacgttggc gcagcggtaa
    10321 gcgcgtgctc atcgcctgtg aagatgaaaa gcaggcttac cggctggatg aagccctgtg
    10381 ggcgcgtccg gcagaaagct ttgttccgca taatttagcg ggagaaggac cgcgcggcgg
    10441 tgcgccggtg gagatcgcct ggccgcaaaa acgcagcagc agcccgcgcg atatattgat
    10501 tagtctgcga acaagctttg cagattttgc caccgctttc acagaagtgg tagacttcgt
    10561 tccttatgaa gattctctga aacaactggc gcgcgaacgc tataaagcct accgcgtggc
    10621 tggtttcaac ctgaatacgg caacctggaa ataatggaaa agacatataa cccacaagat
    10681 atcgaacagc cgctttacga gcactgggaa aagcagggct actttaagcc taatggcgat
    10741 gaaagccagg aaagtttctg catcatgatc ccgccgccga acgtcaccgg cagtttgcat
    10801 atgggtcacg ccttccagca aaccatcatg gataccatga tccgctatca gcgcatgcag
    10861 ggcaaaaaca ccctgtggca ggtcggtact gaccacgccg ggatcgctac ccagatggtc
    10921 gttgagcgca agattgccgc agaagaaggt aaaacccgtc acgactacgg ccgcgaagct
    10981 ttcatcgaca aaatctggga atggaaagcg gaatccggcg gcacgattac ccgtcagatg
    11041 cgccgtctcg gcaactccgt cgactgggag cgtgaacgct tcacgatgga cgaaggcctg
    11101 tccaatgcgg tgaaagaagt tttcgttcgt ctgtataaag aagacctgat ttaccgtggc
    11161 aaacgcctgg taaactggga tccgaaactg cgcaccgcta tctctgacct ggaagtggaa
    11221 aaccgcgaat cgaaaggttc gatgtggcac atccgctatc cgctggctga cggcgcgaaa
    11281 accgcagacg gtaaagatta tctggtggtt gcgactaccc gtccggaaac cctgttgggc
    11341 gataccggcg tggccgttaa cccggaagat ccgcgttaca aagacctgat tggcaaatat
    11401 gtcattctac cgctggttaa ccgtcgtatt ccgatcgttg gcgacgaaca cgccgacatg
    11461 gaaaaaggca ccggctgcgt gaaaatcact ccggcgcacg actttaacga ctatgaagtg
    11521 ggtaaacgtc acgcgctgcc gatgatcaac atcctgacct ttgacggcga tatccgtgaa
    11581 agcgcccagg tgttcgatac caaaggtaac gaatctgacg tttattccag cgaaatcccg
    11641 gcagagttcc agaaactcga gcgttttgct gcacgtaaag cagtcgttgc tgcggttgac
    11701 gcactcggcc tgctggaaga aattaaaccg cacgacctga ccgttcctta cggcgaccgt
    11761 ggcggcgtag ttatcgaacc aatgctgacc gaccagtggt acgtgcgtgc cgatgtactg
    11821 gcgaaaccgg cggttgaagc ggttgagaac ggcgacattc agttcgtacc gaagcagtac
    11881 gaaaacatgt acttctcctg gatgcgcgat attcaggact ggtgtatctc tcgtcagctg
    11941 tggtggggtc accgtatccc tgcatggtac gacgaagcag gtaacgttta tgttggccgc
    12001 aacgaagaag aagtgcgcaa ggaaaataac ctcggtgccg acgttgccct gcgtcaggac
    12061 gaagacgttc tcgacacctg gttctcttct gcactgtgga ccttctctac ccttggctgg
    12121 ccggaaaaca ccgacgccct gcgtcagttc cacccaacca gcgtgatggt atccggcttc
    12181 gacatcatct tcttctggat tgcccgcatg atcatgatga ccatgcactt catcaaagat
    12241 gaaaatggca aaccgcaggt gccgttccac actgtttaca tgaccggtct gattcgtgac
    12301 gacgaaggcc agaagatgtc caaatccaag ggtaacgtta tcgacccgct ggatatggtt
    12361 gacggtattt cgctgccaga actgctggaa aaacgtaccg gcaatatgat gcagccgcag
    12421 ctggcggaca aaatccgtaa gcgcaccgag aaacagttcc cgaacggcat tgagccgcac
    12481 ggcaccgatg ccctgcgctt caccctggcg gcgctggcgt ctaccggtcg tgacatcaac
    12541 tgggatatga agcgcctgga aggttaccgt aacttctgta acaagctgtg gaacgccagc
    12601 cgctttgtgc tgatgaacac ggaaggtcag gattgcggct tcaacggtgg tgaaatgacg
    12661 ctgtcgctgg cggaccgctg gattctggca gagttcaacc agaccatcaa agcgtaccgc
    12721 gaagcgctgg acagcttccg cttcgatatc gctgcaggca ttctgtatga gttcacctgg
    12781 aaccagttct gcgactggta tctggagctg accaagccgg taatgaacgg tggaaccgaa
    12841 gccgaactgc gcggtactcg ccatacgctg gtgactgtac tggaaggtct gctgcgcctc
    12901 gcgcatccga tcattccgtt catcaccgaa accatctggc agcgtgtgaa agtactttgc
    12961 ggtatcactg ccgacaccat catgctgcag ccgttcccgc agtacgatgc atctcaggtt
    13021 gatgaagcgg cgctggccga caccgagtgg ctgaagcagg cgatcgttgc ggtacgtaac
    13081 atccgtgcag aaatgaacat cgcgccgggc aaaccgctgg agctgctgct gcgtggttgc
    13141 agcgcggatg cagaacgtcg cgtaaatgaa aaccgtggct tcctgcaaac cctggcgcgt
    13201 ctggaaagca tcaccgtgct gcctgccgat gacaaaggtc cggtttccgt tacgaagatt
    13261 atcgacggcg cagagctgct gatcccgatg gctggcctca tcaacaaaga agatgagctg
    13321 gcgcgtctgg cgaaagaagt ggcgaagatc gaaggcgaaa tcagccgcat cgagaacaag
    13381 ctggcgaatg aaggctttgt cgcccgcgca ccggaagcgg tcatcgcgaa agagcgtgag
    13441 aagctggaag gctatgcgga agcgaaagcg aagctgattg aacagcaggc tgttatcgcc
    13501 gcgctgtaat caacaccgtg atgaaaacga aggccggagc atgctccggc cttttttatc
    13561 tcttacagaa atggtaaaga aggcataatt ccccgtgaaa tactggctaa gaagccttta
    13621 tctggttgtt cttctttatt gattaaagga aggtcatcca aatcgcccag caaatacgta
    13681 ttttttgcct gccagtcaat catccatatt ttcagcagtg gataagccag accgcccgta
    13741 atcccggata tcaccaccaa cgcacacatg cgataaagca taccgtggta tgttaaagtt
    13801 gagcgaaaac gaatacgccc atcattcagt gacaggttgc tcataaaatg atttcgcaac
    13861 gacaccgtta aataactggt gctaacagca atcccaaaat aatagattaa ctgcgcgatt
    13921 atcattttac gttgcatttc cataaattgc tgtaaattct caatatcatc atttgcatac
    13981 acagaactat catacgcatt taatatttga tcgaagataa tataaccagc aacagcgaga
    14041 aaaggtaata aagctaaaaa tgcgagaatg gcatatttta tacaatacgt agtatctaat
    14101 ttcaccttga aacgatgtat accgaaactg gtattgctcc agagaaaact cattaccaga
    14161 ctatataaag taccattaaa aataccaatg gaaacaatac caactattgc catcagaacc
    14221 acagatataa taacactact tgaactattg gcatgtagca tctttgtcga gataaagaaa
    14281 acagtcccca tcccaatggc cattaaaatc ggcaagaaaa aggttaccca ccagaaccct
    14341 ttcaaagagc aattaaaact aaatcttacg ccgttgagac tagtcatcaa ggcctgataa
    14401 cgcagtcctt ttgctgccat aaatataagc aaaaccaaca gtgacaaagt caaaacacag
    14461 tcaacaagcg gcatatctgc tgacactgtc attaagattg cgaaatagaa aaaaacaaaa
    14521 acaagacaac taacaaaaac attcccaccg gtaatcccat aagaaaatcg ttgtccgtta
    14581 acttccatat tagcatagag ataacgctta catttcatta atgcccatgg taaatagata
    14641 cctagcgtta taatcgttaa caacacattc accacacaaa taagaaaata tctctcacct
    14701 gtaccatgaa aaacaaacga atgggacgga acatccattt cattaataac ttgagccata
    14761 aaaattccct gaattaaaaa attcattgat ataatttata gatacagaca gtaaaatgtt
    14821 ctgccacgtt acaatactct tatcagtaat aggctggcaa aaactttatt gctttataag
    14881 acgcttgcgc acgtaagaag agagtggtat taaacaaatg tataattact ttatttttat
    14941 tgggttaaac tatgaataac attgcgccgc aatcacctgt aatgcgtcgc ctgacgttgc
    15001 aggataatcc tgctatcgcc cgcgtcattc gtcaggtatc cgccgaatac ggtcttaccg
    15061 ctgataaagg ctacaccgtc gccgatccga atcttgacga gctgtatcaa gtgtatagtc
    15121 agcctggtca tgcatattgg gtggttgagt acgagggtga agtggtcggc ggcggtggga
    15181 ttgcgccatt agcaggtagt gaatcggaca tttgcgaact gcaaaagatg tattttcttc
    15241 cggctattcg cggtaaaggg ctggcgaaaa aactggcctt aatggcgatg gagcaagcac
    15301 gagagatggg cttcaaacgc tgctatctgg aaacgaccgc ttttttaaag gaagccattg
    15361 cgctttatga gcatttgggc tttgagcata tcgactatgc gcttggctgc acgggccatg
    15421 tcgattgtga agtgcggatg ctacgcgaac tctaaaaaaa tgcccgctag tgtgtgctat
    15481 cgggcatttt aatcaattaa ttagtggcga acaccgtcat cgtcttcatc gacaaaatct
    15541 tcatcgtcgc cgtcttcgcc attgggatct tcaaagtaag tgccccaacc gtcgtactca
    15601 acgtcaaatt tctccgccag cgtcatcagt tgttcaacct gggcatcgat cagatcggca
    15661 ttcaacgcgc actcgctgag gatgtcgcag caaatcacga tatcaccatc ttcaacttcc
    15721 agctcttctg gatcggtcac ttcgtaaccg agtttaaacg cttcaactgc tgctttttcc
    15781 agggtttcca gatcgtctgc ggaaagatgg tgttcgatgg tgtacagcgc gtccggatcg
    15841 ctgccatctt ccagtaattc ttcaataatc aaacgtgttt cttcacgctg ttcttccagt
    15901 tgttccgggt ttgccatggc tcattcctct taatgtcctg ccgatactct tattgtcaca
    15961 caccactgac attgcctcca cctttgtgac aaagatttat gctttagact tgcaaatgaa
    16021 taatcatcca tataaattga attttaattc attgaggcat tagccacagg agggatctat
    16081 gtccgggttt tatcataagc atttcctgaa attactcgat ttcacgccag ctgaactcaa
    16141 caccttgttg cagttagccg cgaagctgaa agccgataag aaaagcggta aagaagaagc
    16201 taaactcact ggtaaaaaca tcgcgctcat cttcgaaaaa gactcgactc gtacccgatg
    16261 ctctttcgaa gttgccgcat atgaccaggg tgctcgtgtt acttatctcg gcccaagcgg
    16321 cagccagatt ggtcataaag agtcgattaa agacactgcc cgcgtgcttg gtcgcatgta
    16381 tgacggtatt cagtatcgcg gctatggtca ggagattgtc gaaacactgg cggaatacgc
    16441 tggcgtgccg gtatggaacg gcctgaccaa tgagtttcac cccacgcagc tgctggcgga
    16501 tctcctcacc atgcaggagc atttgcccgg taaaacattc aacgaaatga cgctggtcta
    16561 tgcaggtgac gcacgtaaca acatgggcaa ttcgatgctc gaagctgcgg cgcttaccgg
    16621 tctggatttg cgtctggtcg cgccacaggc atgctggccg gaagctgcgc tggttacgga
    16681 atgccgcgct ctggcacagc aaaatggcgg gaatattacg ctgacggaag atgtagccaa
    16741 aggagtagaa ggtgctgact ttatctatac cgatgtgtgg gtgtcgatgg gggaagcaaa
    16801 agagaaatgg gcggaacgaa ttgcattgct gcgtgattat caggtgaata acaagatgat
    16861 gcagttgacc ggtaacccgg aggtcaaatt cctccactgc ctgcccgcat ttcatgacga
    16921 ccaaacgacg cttggcaaga aaatggcgga agagtttggc ctacatggcg gaatggaagt
    16981 gactgatgag gtcttcgaat ctgccgccag cattgtattt gatcaggcgg aaaaccgcat
    17041 gcataccatc aaagcggtga tggtcgcgac gctcagtaaa taattgatat cgctataaag
    17101 atgccgggaa atacaaaact atcccggcat cacattattt tatgcagtga taggtctatt
    17161 cttccaccca attttttcta ttgcagaacg taaatcttgc ggtggattta atttttctaa
    17221 ctgtttttca tta
//
LOCUS       DAPOXO010000101        16577 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPOXO010000101 DAPOXO010000000
VERSION     DAPOXO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.101"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..111
                     /locus_tag="ROH59_004197"
     CDS             <1..111
                     /locus_tag="ROH59_004197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708723.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDX4806607.1"
                     /translation="YVYIILPLSGLVMMFYALCFINQSIQQLKQPAQEAS"
     gene            111..1412
                     /locus_tag="ROH59_004198"
     CDS             111..1412
                     /locus_tag="ROH59_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708726.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HDX4806608.1"
                     /translation="MDSYIALTLFGCFFVLVFIGVPISFSIGIATVASMLLMFPWDIA
                     AITVSQRLANGLDNFALLAIPFFIFAGTLMNSGGIAIRLINLAQVMVGRVPGSLGHVN
                     VLANMMFGSISGSAVAAAAAVGGTLNPIQTKEGYDPAFSTAVNVSSCITGLLIPPSNV
                     LIVFSLTAGGVSVASLFMAGYLPGILMGLAVMIVCGIIAKRRGYPLSERATFAQACKA
                     FLDALPSLLLVFIVMGGILGGIFTATEASAIAVVYTFILSVLIYREVKWRDLPKLILE
                     SVVTTSIVLLLIGFSVGMSWAMTNADIPYMISDALMGISDNPLVILLLINIVLLIVGI
                     FMDMTPAVLIFTPIFLPIAQELGMDPVHFGIMMVANLCIGLLTPPVGSALFVGCSISG
                     VKIQHLIKPLLPFYAALLITLMMITYIPQISLFIPQLLGLM"
     gene            complement(1468..2475)
                     /locus_tag="ROH59_004199"
     CDS             complement(1468..2475)
                     /locus_tag="ROH59_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HDX4806609.1"
                     /translation="MKKQWIVGTALLMLMTGNVWADGEPPTENILKDQFKKQYHGILK
                     LDAITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     NQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDEFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVSIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWITLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVI
                     K"
     gene            complement(2592..3638)
                     /gene="ansB"
                     /locus_tag="ROH59_004200"
     CDS             complement(2592..3638)
                     /gene="ansB"
                     /locus_tag="ROH59_004200"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HDX4806610.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKTVF
                     DTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            complement(3814..4533)
                     /locus_tag="ROH59_004201"
     CDS             complement(3814..4533)
                     /locus_tag="ROH59_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HDX4806611.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            complement(4554..4694)
                     /locus_tag="ROH59_004202"
     CDS             complement(4554..4694)
                     /locus_tag="ROH59_004202"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806612.1"
                     /translation="MQNCLMRYAYQAWKDAQSSRPDKAFTPHPAWMTCTLLSIWGQQM
                     LA"
     gene            complement(4717..5043)
                     /locus_tag="ROH59_004203"
     CDS             complement(4717..5043)
                     /locus_tag="ROH59_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HDX4806613.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLGEVRTSEL
                     FDVWWD"
     gene            complement(5043..5762)
                     /gene="trmB"
                     /locus_tag="ROH59_004204"
     CDS             complement(5043..5762)
                     /gene="trmB"
                     /locus_tag="ROH59_004204"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDX4806614.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            5923..6975
                     /gene="mutY"
                     /locus_tag="ROH59_004205"
     CDS             5923..6975
                     /gene="mutY"
                     /locus_tag="ROH59_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDX4806615.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQ
                     VATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIATANNSWSL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEDNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            7003..7278
                     /locus_tag="ROH59_004206"
     CDS             7003..7278
                     /locus_tag="ROH59_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HDX4806616.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK"
     gene            7343..8422
                     /gene="mltC"
                     /locus_tag="ROH59_004207"
     CDS             7343..8422
                     /gene="mltC"
                     /locus_tag="ROH59_004207"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HDX4806617.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            8624..9880
                     /gene="nupG"
                     /locus_tag="ROH59_004208"
     CDS             8624..9880
                     /gene="nupG"
                     /locus_tag="ROH59_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupG"
                     /protein_id="HDX4806618.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAVLVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(9929..12064)
                     /gene="speC"
                     /locus_tag="ROH59_004209"
     CDS             complement(9929..12064)
                     /gene="speC"
                     /locus_tag="ROH59_004209"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HDX4806619.1"
                     /translation="MKSMNIAASSELVSRLSTHRRVVALADTDFTDVAAVVITAADSR
                     SGILALLKRTGFHLPVFLYSEHVVELPAGVTAVINGNEQQWLELESAACQYEENLLPP
                     FYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVALGIEARKAILARCKLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFCVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDANGMKRLYGYVLK"
     gene            12457..13164
                     /locus_tag="ROH59_004210"
     CDS             12457..13164
                     /locus_tag="ROH59_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDX4806620.1"
                     /translation="MVIGPFINASAVLLGGVLGALLSQRLPERIRVSMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEICLLEKGVNTAVTKAQNLFRHSRKKPAHESF
                     IQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            13270..13345
                     /locus_tag="ROH59_004211"
     tRNA            13270..13345
                     /locus_tag="ROH59_004211"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13303..13305,aa:Phe,seq:gaa)
     gene            13543..14808
                     /locus_tag="ROH59_004212"
     CDS             13543..14808
                     /locus_tag="ROH59_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDX4806621.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLISEGVDPCEQKRAKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLSTPDLLIPVRAAEVKQIYEI
                     ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLSRIDG
                     YKGQPVTRLAVMLNLLVFIRSSELRYARWSEIDIDNAMWTIPAEREPLPGVKFSYRGS
                     KMRTPHLVPLSQQAVAILAELQTWAGENGLIFTGAHDPRKPISENTVNKALRVMGYDT
                     TKEVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLML
                     QWWADFLDANREECISPFEYAKVNNPLKR"
     gene            15064..16107
                     /locus_tag="ROH59_004213"
     CDS             15064..16107
                     /locus_tag="ROH59_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDX4806622.1"
                     /translation="MTGKLRFEVNDNQGCFIFPETWFGSLLDEFEELIDAYDADEISE
                     TSYINKLRRLARQENDFIDVHAHLAYVFLEQNAPRKALNAALKGLAIGNRLIPEGFSG
                     RIIWIHPDNRPFLRALYAAILANAHLQRHQDAIMLIEKILDYNPEDNHGARWLLGPEL
                     LRTGAHEQARHILQEHADEFSPYWYELGLLHFLNGELVKAATAFRRGFAANTYIAEIL
                     CGNLHPFPLAVWHNFSGGPDTAEDYYATYHPLWGQYPEALLFVNWLYNHSSVLHERAE
                     IIKCAEMLMQEDDFEICESILRQQEKLRERIDETLSEKIVQKCRNMNGEYIWPWILPF
                     SAAGMKHTGIQYQ"
BASE COUNT         4047 a         4227 c         3956 g         4347 t
ORIGIN      
        1 tacgtatata tcattctgcc attaagtgga ttggtgatga tgttttatgc cttgtgtttt
       61 attaatcaaa gcattcaaca actgaaacaa cctgcgcagg aggccagtta atggatagtt
      121 atatcgcgct tacactgttt ggctgttttt ttgtgctggt ctttattggt gtgcccattt
      181 cgttctcaat cggtattgcc actgtagctt caatgctgtt gatgtttccc tgggatatcg
      241 cggcaatcac tgtttcgcag cgactggcta atggactgga taactttgcc ctattggcaa
      301 tccccttttt catctttgcc ggaacgctga tgaacagcgg cggtattgcg atacgtttga
      361 ttaacctcgc ccaggtaatg gttggccgcg ttcctggttc gcttggtcat gtgaacgtcc
      421 tggcgaatat gatgtttggt tccatttctg gttcagctgt tgcggcagct gctgccgttg
      481 gtggcacact gaatcccatt cagaccaaag aaggttatga tccggcattt tctaccgctg
      541 taaacgtctc atcttgtatt actggattac tgataccgcc ctcaaacgtg ttaattgtgt
      601 tttccctgac agctggcggc gtttctgtag catcgctatt tatggcggga tatttgccag
      661 ggatcttaat gggtctcgcg gtaatgatag tctgcggcat tattgctaaa cgccgtggct
      721 acccactttc agaaagagca acctttgctc aggcatgtaa agcgtttctg gatgccttac
      781 caagtttgct tctggtgttc attgtaatgg gcggcattct gggcggcatt tttaccgcaa
      841 ctgaagcgtc agcaattgcc gttgtctaca catttattct ctcggtgctg atttaccggg
      901 aagtaaaatg gcgcgattta cccaaactga ttctggaatc ggttgttacc acttcgattg
      961 tattactgtt gatcggtttt tccgtgggca tgtcctgggc aatgaccaat gctgatattc
     1021 cttatatgat cagcgacgcg ttgatgggga tttctgataa cccactggtc atattgctgc
     1081 tgattaatat cgtcttatta attgtcggca tctttatgga catgacaccg gctgtactaa
     1141 tcttcacacc aatcttcttg ccgattgcac aagagctggg aatggatccg gtacatttcg
     1201 gtattatgat ggtggccaac ctttgtattg ggctgttaac accgccggtg ggtagtgcgc
     1261 tatttgttgg ttgttctatt tcaggtgtga agattcaaca tttgatcaaa ccattgctgc
     1321 cattttatgc cgcattgtta atcacgttga tgatgatcac ttacatcccg caaatatcct
     1381 tgttcattcc acagctacta gggctaatgt aaaaaataat ttgccggata actttttata
     1441 ttatccggca aaggtactta acatgagtta cttaatcact ccattgcgcc gcaattgttc
     1501 ggtatctttt ttccagcgtt cattagcctg attgatatcg tcaattttca tcaaaatcgc
     1561 gactttttta ctgtttattt ctgaaacttt catcgttaac ggatattgcc ctttctcgag
     1621 cgttatccag tcatcctgca atttacggct aagtttttgt gattgcagaa aagtctgtcg
     1681 ccgttgttcg ttgatatcga aatctcgctt ctgctgaatc gacacttcat aacactcttc
     1741 actctgttta tgacatgccg caatcgccgg ttgataaacc tctttgtcat atttaaccgc
     1801 gaacgcctcg ctatcattct gtttattaaa ctcatcacgc tgttggtgaa tttttttaaa
     1861 ggcgtcttcg cgggtcattt gcttaccgtt tgcatctttt ccccaatatg catccgctgc
     1921 tttctgcgcc gccaccattt gcttatcaag cgctttcact tccttttcca gcgcaggaat
     1981 cgagttcttc tggttattca acgcagactc aagctgacta aagcgataat tgaaatcttc
     2041 gctattcacg atcagatatt tattattcgt tttgatatcg tcgaccaccc gcccacgatc
     2101 gctggctgcc gcctgaaaag agtaaaagtt caccgaccag ccagacgcgg gcgttccttt
     2161 actggttaac atcgccgaga attttaccgg tttatctttc gtccaggtct gttcgagcag
     2221 ttcgtaatct gccaactgac cgacccaggt atagagatcg tcactggaag agacatcgcc
     2281 ttccgctgac caggtggcct gattaccctt agcatcaaga ttttttaagg tgatagcatc
     2341 aagcttgaga atgccgtgat actgcttttt gaattgatct tttaagatat tttcagttgg
     2401 cggttcgcca tctgcccaga cattaccagt catcaacata agcagcgccg tgccaacaat
     2461 ccattgcttt ttcacccgaa aaccctcgcg cggaataatt tattccagtg attatcatca
     2521 gggtaatgaa aattggcaat ggacgtaagt ctgaagtgaa aaagccccgg cacgataccg
     2581 gggcgaggtg attagtactg attgaagatc tgctggatct gctgcggatc tttggtttgc
     2641 gtcagagcca gctgcagcag gacgcgcgct ttttgcgggt tcagcgtgcc agaggcgacg
     2701 aagccgtatt tcgcatcatc cacttcagca tcctgagtgg tagcgcccgt cggtacacgg
     2761 gaagaacgca ctactgcagt gccgtttttc gcggcggttg caagggtgtc aaatacggtt
     2821 ttatacaggt tgccgttacc cacaccagcg ctgacgatgc catcatagcc cgcatctacc
     2881 agtgctttag ccggaagatc ggatgcgtta gcgtagttat aaacgatgcc gactttcggc
     2941 agctcattca gcttagagac atcgaatggc gtatcgctgg tgtgcttacg tgccggggta
     3001 cgttggtagt caatcttacc gttgtgaatg taacccagag gaccgtagtt aacagacttg
     3061 aaggtcgcta cgtcggtggt gttggttttg gtgacatcgc gaccgtccag tacggtgtcg
     3121 ttcatcacca ccagtacgcc acgattagcg gaggctttat cagctgcggt cactaccgcg
     3181 ttatacaggt tgaatggacc gtctgcgctc atagacgtgg acgggcgcat tgcaccgacc
     3241 atcaccaccg gtttgtcgca tttcaccgtc aggtcgagga agtaagcggt ttcttccatc
     3301 gtgtcggtac cgtgagtaat gacgaagccg tcggttttat cgcagtcggt gttaattttt
     3361 ttcgccagtg tcagccagac attatcgttc atgtcctggg agccgatatt cactacctgc
     3421 tcgcctttaa cgttcgcaat gtccttcagt tgcggcaccg cattaaccag attttctacg
     3481 ccaactttac ccgctgtgta gttagatttg gttgcggagt caccaccacc ggcaatggtc
     3541 ccgccggttg ctaaaatggt gatattgggt aatgccaatg ctgcaccact aaaacccata
     3601 accagtgcgg caagtgccgt ctttttgaaa aactccattt cattcctcca gttacgtgaa
     3661 cgctacgcat tatcccttag ctttgtatgg gaaatttgac gttaaacaat ttacaacgtg
     3721 aatatatttt ggagatctac aaagttagag gcaggtaaca aaacgaagaa ttaaacggca
     3781 taaaaaagta ttatgccgtc ttaaaataga ggattatttt aaattcccga ccagggcttt
     3841 gcgactatct tccagagtca caacgcggct acaaacatct ttgccaaact gctggaaatc
     3901 tttttcctgc tttttccatt cggtttggat tgaggattgc agaccgccca ggcttcccag
     3961 cacattctgt aatgggttac caccgctttt cagcaccgct ttcgcgccca tttcattaat
     4021 gctgtcctgt aaaattccgc ccattgcctg attcactaat tgctggcctt cggcgcgaac
     4081 ctgatcaatg gctttatagt gaaacgtcag gccatcgctg cgcgtttcga taatgcggtt
     4141 catctgctct ttcagctgcg catcaagttt ggtcagacgg ctgcgcattt tgctgctttc
     4201 gcccatctcc tgaacgataa ttttatccag cgcaatacgg gctttctcga cgcggctttt
     4261 cgcgccttca tcaatccacg gcagggtgct acgcagttca gcctgataat ccttcgcctg
     4321 ctcgcgctgg gcggcgttca gggaatattg cttaccgtta tacatcacgt tgccgtctgg
     4381 cgtgatcacc agattgccgt tttcgccctt cacctgcacg gtttgcgggc tgacaatcac
     4441 atcgtcacgc ggcgtgacgc tgcactggta gtcggcgtga gcggtcattg ccgtcactga
     4501 aagtgctgcc gccagcagca ttttgcgcat catagtcttc cctcaagaac aaatcaggcc
     4561 agcatttgct ggccccagat tgataacaaa gtacatgtca tccatgccgg atgcggcgta
     4621 aacgccttat ccggcctact cgattgtgca tctttccagg cctgataagc gtagcgcatc
     4681 agacagtttt gcatttgtca tcgcccgtat gttttcttag tcccaccaaa cgtcgaaaag
     4741 ttcgctggtg cgtacctcgc ccagtttgcg ctcttccagc cacttacgca caatcgcctg
     4801 atgttcttcg gtgcatttgc cgatttcctg catgcagatc agaccttccc aggccagata
     4861 accgctgccg tcaaaggcca gtttgttcgg ttcgataacc tcgttaataa agtcatcaac
     4921 ggttttatca atctgttctt ccgatgtacc ttccgggaat cgccatgcca ccgaaaatcc
     4981 taattcctgg aattcgtcga tgtgcatttt tttacgcaga cgacggctac ggttctttgc
     5041 cattatttca ccctctcgaa cattaagtcc catactccgt gaccaagacg atgaccacgt
     5101 tgttcaaatt tcgtcaccgg acgtgatgcc ggacgcggta cgtaatcatt gctctctgac
     5161 aggtttttat aaccgtcaat agaagacatc acttcaagca tatgttccgc ataaggttcc
     5221 cagtcggtcg ccatatggaa tacgcccccc agctgcagtt tgctttttac cagttcggca
     5281 aacggcacct gaacgatacg gcgtttatta tggcgcgctt tgtgccacgg gtcagggaaa
     5341 aagagctgca ccatgcgcaa tgaattgtca ggaatcattt tatgcagcac ttcaaccgca
     5401 tcgtgacaca tcacgcgcag gttgcttaag ccctcttcat gcgcagaagc caggcacgca
     5461 ccaacgcccg gtgaatgcac ttcaatgccg aggaagtcct gctcggggcg atctttagcc
     5521 attgccacca gcgacgcccc catgccgaaa ccaatctcaa gcgtcaccgg cgcttcacgg
     5581 ccaaaaagcg cagggaaatc cagcatatct tcgctgaact caacgcccat caccggccag
     5641 tagttttcca gcgcatgttc ctggcctttg gtcagtcgcc cctggcggcg cacaaaacta
     5701 cggatacggc gcagtgggcg gccgttttca tcaaattccg gtgagatgac gtcgtttttc
     5761 ataaagattt agtcgcttgt gaaagtgttc tgaaaacggg cattatccaa agttagttgc
     5821 cggatgcaag catgataagg ccgtggctgc ggaaagttcc ggtttacacc ctgccgtcgc
     5881 tgtgctgcaa tcttgccccc aacaacagtg aattcggtga ccatgcaagc gtcgcaattt
     5941 tcagcccagg ttctggactg gtacgataaa tacgggcgga aaacgctgcc ctggcaaatt
     6001 gacaagacgc cctacaaagt atggctctca gaagtgatgt tgcaacaaac tcaggttgcg
     6061 accgttatcc cctattttga acgctttatg gcgcgcttcc caacggtgac cgatctcgcc
     6121 aatgcgccgc tcgacgaagt tctccacttg tggaccgggc ttggctatta cgcccgcgcg
     6181 cgcaatctgc ataaagcggc acagcaagtg gcgaccttac acggcggtaa attcccggaa
     6241 acctttgaag aagtcgcggc gttaccgggc gtcgggcgtt ccaccgcagg cgcgattctc
     6301 tcgctttctc tgggtaagca ctttccgatt ctcgacggta acgtcaaacg ggtgctggcg
     6361 cgctgctatg ctgtaagcgg ctggcccggg aaaaaagagg tcgagaataa attatggagt
     6421 ttgagcgagc aggtgacgcc cgctgtcggc gtggaacggt ttaatcaggc gatgatggat
     6481 ttaggcgcga tgatttgtac gcgctcgaag ccgaaatgtt cgctctgtcc gctacaaaac
     6541 ggatgtattg ccaccgccaa caatagctgg tcgctttatc cgggcaaaaa accgaaacag
     6601 acgctgccgg agcgcaccgg ctactttctg ctgttacagc acgaagatga agtattgctg
     6661 gcgcagcgcc cgccgagtgg attgtggggc ggtttatact gtttcccaca gtttgccgac
     6721 gaagaaagtt tgcggcagtg gctggcgcaa cggcagattg ctgccgataa cctgacgcaa
     6781 ctgaccgcgt ttcggcatac cttcagccat ttccacttag atattgtgcc tatgtggctt
     6841 cccgtgtcgt cattcaccgg ctgcatggat gaagacaatg cgctctggta taacttagcg
     6901 caaccgccgt cagttggcct ggcggctccc gtggagcgtt tgttacagca gttacgcact
     6961 ggcgcgccgg tttagcgcgt gagtcgataa agaggatgat ttatgagcag aacgattttt
     7021 tgtactttcc tgcaacgtga agcagaaggt caggattttc agctgtaccc cggcgagctg
     7081 ggaaaacgca tctataacga gatctccaaa gaagcctggg cgcagtggca gcacaaacaa
     7141 accatgctga ttaatgaaaa gaaactcaac atgatgaatg ccgagcaccg caagctgctg
     7201 gagcaggaga tggtcaactt cctgttcgag ggtaaagagg tgcatatcga gggctatacg
     7261 ccggaagata aaaaataaaa acagtgccgg agcacgcctc cggcaacttg cataaaaaca
     7321 aacacaacac gcacccggaa tgatgaaaaa atatctcgcg ctggctttga ttgcgccgtt
     7381 gctcatctcc tgttcgacga ccaaaaaagg cgatacctat aacgaagcct gggtcaaaga
     7441 taccaacggt tttgatattc tgatggggca atttgcccac aatattgaga acatctgggg
     7501 cttcaaagag gtggtgatcg ccggtcctaa ggactacgtg aaatacaccg atcaatatca
     7561 gacccgcagc cacatcaact tcgatgacgg tacgattact atcgaaacca tcgccgggac
     7621 agaacctgcc gcgcatttgc gccgggcaat aatcaaaacg ttgctgatgg gggacgatcc
     7681 gagttcggtc gatctctatt ccgacgttga tgatattacg atttcgaaag aacctttcct
     7741 ttacggtcag gtggtggaca acaccgggca gccgattcgc tgggaaggtc gcgcgagcaa
     7801 cttcgcggat tatctgctga aaaaccgtct gaagagccgc agcaacgggc tgcgtatcat
     7861 ctacagcgtc accattaaca tggtgccgaa ccaccttgat aaacgtgcgc acaaatatct
     7921 cggtatggtc cgccaggcgt cacgcaaata tggcgttgat gagtcgctga ttctggcaat
     7981 tatgcagact gaatcttcct ttaacccgta tgcggtcagc cgttccgatg cgctgggatt
     8041 aatgcaggtg gtacaacata ccgccgggaa agatgtgttc cgctcgcagg ggaaatccgg
     8101 cacgccgagc cgcagtttct tgtttgatcc tgccagcaat attgataccg gcaccgcgta
     8161 tctggcgatg ctgaacaacg tttatctcgg cggaattgat aacccaacat cgcggcgtta
     8221 tgccgtcatc accgcctata acggcggcgc aggcagcgtg ctacgagtct tttcgaatga
     8281 taagattcag gctgccaata ttattaacac catgacgccg ggcgatgttt atcagacgct
     8341 gacgacccgc catccctctg cggaatctcg ccgttatctt tataaagtga ataccgcgca
     8401 aaaatcttac cgccgccgat aattccacta accgcccctg acgatgctca ggggtaaaaa
     8461 tgttatccac atcacaattt cgttttgcaa attgggaatg tttgcaatta tttgccacag
     8521 gtaacaaaaa accagtccgc gaagttgata gaatcgcatc atctcgcacg gtcaaatgtg
     8581 ctttttcaaa cactcatccg catcacgatg tgaggaaatt aacatgaatc ttaagctgca
     8641 gctgaaaatc ctctcttttc tgcagttctg tctgtgggga agttggctga cgaccctcgg
     8701 ctcctatatg tttgttaccc tgaagtttga cggtgcttct atcggcgcag tttatagctc
     8761 actgggtatc gccgcggtct ttatgcctgc gctgctgggg attgtggccg acaaatggtt
     8821 aagtgcgaaa tgggtctatg ccatttgcca caccattggc gctatcacgc tgttcatggc
     8881 ggcagaggtc actacgccgg aggcgatgtt ccttgtgata ttgattaact cgtttgctta
     8941 tatgccaacg cttgggttaa tcaacaccat ctcttactat cgcctgcaaa atgccgggat
     9001 ggatatcgtt actgacttcc cgccaatccg tatctggggc accatcggct ttatcatggc
     9061 aatgtgggtg gtgagcctgt ccggcttcga attaagccac atgcagctgt atattggcgc
     9121 agctctttcc gccgttctgg ttctgtttac cctgactctg ccgcatattc cggttgctaa
     9181 acagcaagcg aatcagagct ggacaaccct gctgggcctc gatgcattcg cgctgtttaa
     9241 aaacaagcgt atggcaatct tcttcatctt ctcaatgctg ctgggcgcgg aactgcagat
     9301 taccaacatg ttcggtaata ccttcctgca cagcttcgac aaagatccga tgtttgccag
     9361 cagcttcatc gtgcagcatg cgtcaatcat catgtcgatt tcgcagatct ctgaaaccct
     9421 gttcattctg accatcccgt tcttcttaag ccgctacggt attaagaacg taatgatgat
     9481 cagtattgta gcgtggatcc tgcgttttgc tctgtttgct tacggcgacc cgactccgtt
     9541 cggtactgta ctgctggtac tgtcgatgat cgtttacggt tgcgcattcg acttcttcaa
     9601 catctctggt tcggtgtttg tcgaaaaaga agttagtccg gcaattcgcg ccagcgcgca
     9661 ggggatgttc ctgatgatga ccaacggctt cggctgtatc ctcggcggca tcgtgagcgg
     9721 taaagtggtt gagatgtaca cccaaaacgg cattaccgac tggcagaccg tatggctgat
     9781 tttcgcaggt tactccgtgg ttctggcctt cgcgttcatg gcgatgttca aatataaaca
     9841 cgttcgtgtc ccgacaggta cacagacggt tagccactaa ttacgcaaag aaaaacgggt
     9901 cgccagaagg tgacccgttt ttttattctt acttcaacac ataaccgtac aaccgtttca
     9961 tgccattcgc atcggtttcg ctatagacac cttgcaactc cggcgaaaat cccggcaaca
    10021 aattcacgcc ttcttccagc gcaaggaaat aacgttgaac cgccccaccc cagacttccc
    10081 cgggtaccac gcaaagcacg ccaggtggat aaggcaacgc cccttctgcc gcaattcgcc
    10141 cttcggcatc acgaatccgc accaactcca cttcaccgcg aatataagcg ctatgcgcat
    10201 cctggggatt catcaccact gacgggaaac tctgctggcg gaacatcgct ttttgtaggt
    10261 ctttgacgtc gaaactgaca tacagatcgt gcatctcctg acacaactga cgcagggtgt
    10321 agtcgcgata gcgcaccgga tatttgttat aaacgctcgg caacacctca gccagcggcg
    10381 agtcatcctc aatatgctgt tcaaactgcg ccagcatcgc caccagttgt gccagcttct
    10441 cgtggctttc cgccggagtt aataagaaca gaatggagtt gagatcgcac ttctccggca
    10501 caatgccgtt ctcacgcagg tagtgcgcca gaatcgtcgc tggaacgcaa aaatcgctat
    10561 attcgccggt ttcggcatcg atacccggcg tggtgagtaa cagcttgcac ggatcaacaa
    10621 aatactgatc cgcggcatat ccttcaaagc cgtgccactt cgcccccggc tcaaaactga
    10681 aaaaacggcg gtcgctggct aacactgacg tcggataatc ctgccacaat ttgccatcaa
    10741 caacgggcgg gataaacggg cggaacagct tacagcgcgc aagaatcgcc ttccgggctt
    10801 caatccccaa cgcaacgcac tccgcccaca gccgacgccc actctcccct tcatgaattt
    10861 tggcgttaac gtccagcgcg gcgaacagcg gatagaacgg gctggtagaa gcatggagca
    10921 taaaggcatt attcaaccgc ttatgcgggc aaaaacgcgc ctgtccacgg atatggttat
    10981 cttttttatg gatctgcgac gtctgtgaga atcccgcctg ctgtttgtgc accgactggg
    11041 tcacaaagat ccccggatcg ttttcgttaa gttctaacag cagcggcgag ctatccgcca
    11101 tcatcgggat aaactgttcg taaccgaccc acgcggaatc aaacagaatg taatcacaca
    11161 gatgcccaac ggtatcgatc acctgacggg cgttatagac agtgccgtca taggttccca
    11221 gctgaataat cgccaggcga aacgggcgcg gcaggtcggc tttttctggc gcaacgtcgc
    11281 gaatttgctg gcgcagatac tcttcattaa aacagtgcgc atcaataccg ccaatgaaac
    11341 caaacgggtt acgtgaagct tccagataga ccggcgtcgc ccccgcctga atcaacgcgc
    11401 cgtgatgatt cgacttatgg ttgttacggt cgaagagcac caaatcgcca cgcgttaaca
    11461 gcgcattcgt caccacttta ttcgctgccg atgtgccgtt cagcacaaaa taggttttat
    11521 cggcatgaaa gactttggct gcgaatttct gcgcatcttt cgccgatcct tcatgaatca
    11581 gcagatcgcc caattttacg tcagcgttac acatatcggc gcgaaagatg ttctcgccaa
    11641 agaaatcgta aaaatggcgt ccggcaggat gctttttaaa gaacgcacca tgttgatgtc
    11701 cagggcaagc aaaggtgcta ttacccatct caacgtactg cgtcagcgtg tcataaaacg
    11761 gtggcagcaa attctcttca tactgacagg ctgcggattc cagctccagc cactgctgct
    11821 cgttgccgtt gattaccgcc gtaacgcccg caggtaattc aacaacatgt tcggaataca
    11881 aaaacaccgg tagatgaaaa ccggtgcgct taagcaacgc aagaatgcca ctgcgactat
    11941 ccgcagcggt aatgacgact gccgcgacgt ccgtaaaatc agtatctgcc aacgccacca
    12001 cgcggcgatg agtagaaagt cgggatacca gttcactact ggcggcaata ttcattgatt
    12061 tcataagcgc aaaacccgtt tcggggaagt aagaataccg gacaaggtga aaaaccctgc
    12121 cccacgagat atgggtcaaa ctggtcacca gctccgaccg ccagacatca gtaaaagcag
    12181 aaacgctctg attttactgt tgtcctgcag tgagcgtgcg ttaacttcac cgcatgagca
    12241 gaaaaaggga ggagtttcgc gcgaaacggc gataagcgag agaatgtaag gaggtggcgt
    12301 gcatcgggca aactccgtac agagaggaga aaattcgcgc aatcatggca cctttcgcta
    12361 aagcgtgcaa gccaggactt tgcgaccaga caagccatca acaaggcaaa aagttcataa
    12421 taagaaaatc aaacaataca gttaacagga actcttgtgg tcatcggccc ttttatcaac
    12481 gctagtgcag tcttactggg tggcgttctc ggcgcactgc tcagccaacg cttaccggaa
    12541 cgtatccgcg tctccatgac atcaattttt ggtctggcat cgctggggat tggtatttta
    12601 ctggtggtga aatgcgccaa ccttccggcg atggttttag caaccttact cggtgcatta
    12661 atcggcgaaa tttgtctgct ggaaaaaggc gtcaataccg cggtcaccaa agcacaaaat
    12721 ctgtttcgcc actcacgtaa gaagccagcg catgaatctt ttattcagaa ttatgtcgcg
    12781 attattgtcc tgttttgcgc cagcggcacc gggatcttcg gggcgatgaa cgaagggatg
    12841 accggcgatc cgagtatttt aatcgccaag tcatttcttg atttctttac ggcgatgatc
    12901 ttcgcctgct cgctgggtat tgcggtatcg gtgattagta tcccattact gatcatccag
    12961 ttaacgctgg cgtgggctgc cgcgctgata ttaccgctga ccacaccgtc gatgatggca
    13021 gacttcagcg ccgtaggcgg tttattgctg ctggcaaccg gattacgcat ctgtggcatt
    13081 aaaatgttcc cggtggtcaa catgcttcca gcactccttc tggcaatgcc cctttccgcc
    13141 gcctggaccg cctggtttgc ctgacaatgc gtgcattagc ggcaaagtga tgatagattg
    13201 tgcagtctgc agtaaattga agaaatttga ttgacgagac gaggcgaatc aggtttaatg
    13261 cgccccgttg cccggatagc tcagtcggta gagcagggga ttgaaaatcc ccgtgtcctt
    13321 ggttcgattc cgagtccggg caccaagttc atatcaacgg acctccacgg aggtccgttt
    13381 ttcgtttcag aacgccacaa tttaagcgtt ctgcctccaa atcaattcta ccgaactcaa
    13441 ccagattccc cccacatcaa ccccattgtg tgggtataat tgcgggtata ccccagttcg
    13501 acagaatttg taccctcttt aacgcattca gaaggctgaa ctatggcact gactgacgca
    13561 aaaatccggg ctgcaaagcc cactgacaag gcttataaac tcactgacgg ggctggcatg
    13621 ttcctgctgg tacatcctaa tggttcccgt tactggcgtc tccgttatcg tattctgggt
    13681 aaggagaaaa ccctggcact tggtgtgtat ccggaagttt ctctctccga agctcgtaca
    13741 aaacgggatg aggcccgaaa actgatttcg gagggggttg acccttgcga acagaaaaga
    13801 gctaaaaaag tagtccctga tttacagctc tcttttgaac atattgcacg acgctggcat
    13861 gccagtaata aacaatgggc acaatcacac agcgataaag tactcaaaag cctcgagact
    13921 cacgttttcc cctttatcgg caaccgggat atcacaacac tcagtacccc ggatctgctt
    13981 atccctgttc gtgctgcaga agttaaacaa atttatgaaa tcgccagtcg tctgcagcaa
    14041 agaatatctg ctgtaatgcg ttatgccgta cagtctggca tcatcagata taacccggct
    14101 ctggatatgg ctggtgcatt gaccacggta aaacgccagc atcgccctgc tctggatctt
    14161 tcacgcctgc ctgaacttct gtcgcgtatt gacggttata aaggccagcc tgtcacccga
    14221 ctggcagtta tgctgaattt actggttttt attcgttcca gtgaactcag atatgcccgc
    14281 tggtctgaaa ttgatattga caatgccatg tggactattc cagccgaacg cgaacctctg
    14341 ccaggcgtaa aattttcata ccggggctcc aagatgcgaa caccacatct tgtgccactc
    14401 agccaacagg ctgtagccat actggcagaa cttcagacat gggcaggtga aaatggtctg
    14461 atctttacgg gagcacacga cccacgtaaa ccaatcagtg aaaataccgt aaataaggcc
    14521 ctcagagtga tggggtatga cacaaccaag gaagtctgtg gccatggatt ccgggcgatg
    14581 gcgtgcagtg cattgattga atccggctta tggtcaagag atgcggttga acgtcagatg
    14641 agtcatcagg agcgcaacgg agtacgtgcc gcgtatattc ataaagcaga acatctggaa
    14701 gaacgtcggc ttatgctgca atggtgggca gattttctgg atgcaaacag ggaggagtgt
    14761 atcagtccgt ttgaatatgc aaaagttaac aatccactga aaaggtgact gaacgccatt
    14821 tacacacatg ctcttcctct taaggggaag agcacccgcc tcaatcaatt tcttttttat
    14881 gccggcggaa ccatcagcca ggctgaggtt ctcattcaat aactcaacgt cttaccacag
    14941 aacagaattc actgtattat catgggcaac gttaatcccg gacaataaaa ggacaccgat
    15001 gccaggcatc acaattttta tagcctgcag gttatggtcc atcctttttt acaggttcag
    15061 aatatgactg gcaaattacg ctttgaagtg aacgataacc agggctgttt catatttccg
    15121 gaaacctggt ttggctcgtt gctggatgag tttgaagaac tgattgatgc atacgatgcg
    15181 gatgaaatca gcgaaacaag ttacatcaac aaactcaggc gccttgcccg acaggagaat
    15241 gactttattg atgtacacgc tcacttggca tacgtatttc tggagcagaa tgccccgcgt
    15301 aaggcgctga atgctgccct taaagggctg gcaattggca atcgtcttat ccctgaaggt
    15361 ttcagtggca gaatcatctg gatacatcct gacaaccgac cttttcttcg tgccctctat
    15421 gcggcaatcc tggcaaatgc acatttacag cgtcatcagg atgccatcat gctcattgaa
    15481 aaaatactgg attacaatcc cgaagataat catggtgcac gctggctact gggaccggaa
    15541 ctgttacgca ctggcgctca tgaacaggca cgccatatac tgcaggaaca tgcagatgaa
    15601 ttttcacctt actggtatga actcggcctt ctgcattttc ttaatgggga actggtaaaa
    15661 gctgcaactg catttcgtcg cggctttgcg gcaaatactt acatcgcaga aatactgtgc
    15721 ggaaatctgc atccatttcc acttgctgta tggcataact tttcaggcgg tccggatact
    15781 gccgaagatt attatgccac ataccacccg ttatgggggc aatatccgga agcattgctg
    15841 tttgtaaact ggctctataa tcattcctct gtgctgcatg aacgggcaga aatcattaaa
    15901 tgcgccgaaa tgctgatgca ggaagatgat ttcgaaatat gcgaaagtat tttaagacag
    15961 caggagaagt tgcgtgaaag aattgatgag acgctttctg agaaaattgt acagaaatgc
    16021 agaaatatga atggtgaata tatctggccc tggatattgc cgttttcagc ggcaggcatg
    16081 aaacatactg gcatacagta tcagtagata ttgcattagt gtatcctgca cacaagtaat
    16141 aatttattca ccaataataa cactgttaat gcccccttcc cctggttgtc agccaggggt
    16201 tatcttctga atatttcttt tgaaaaggat aacacagtaa attattttta tgaattatcc
    16261 catggactca ttaacaccct ttcatgatgc tttattgtca aacacgttat ggctgacatc
    16321 aaaaaaaacc ggatttcctc tgccagcggg taatcacctt cccggtgttt tcggttggtc
    16381 tggttactcc tgtctggtta ttagcaagat aattgctata aacagtggaa aactcatcgt
    16441 acataatctg gtgatgaaca ttacgcttat tttcccttga ccggaagaat cagaggctgt
    16501 ggtttcagac tgtctgccag tacattcctc tctccgttaa aaaccataac gggttcatta
    16561 tcttcgtctg tcagcag
//
LOCUS       DAPOXO010000102        16137 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.102, whole genome shotgun sequence.
ACCESSION   DAPOXO010000102 DAPOXO010000000
VERSION     DAPOXO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16137
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.102"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1961)
                     /gene="speA"
                     /locus_tag="ROH59_004214"
     CDS             complement(<1..1961)
                     /gene="speA"
                     /locus_tag="ROH59_004214"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HDX4806623.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYT"
     gene            complement(1970..2101)
                     /gene="yqgB"
                     /locus_tag="ROH59_004215"
     CDS             complement(1970..2101)
                     /gene="yqgB"
                     /locus_tag="ROH59_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HDX4806624.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            2237..2452
                     /locus_tag="ROH59_004216"
     CDS             2237..2452
                     /locus_tag="ROH59_004216"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806625.1"
                     /translation="MGITSAGMQSRDAECGERIFTRTVRQVKQQTTVHYFVSPPRPPV
                     KTNPQAKTLFSTRLEVATRKKRRVLFI"
     gene            2756..3910
                     /gene="metK"
                     /locus_tag="ROH59_004217"
     CDS             2756..3910
                     /gene="metK"
                     /locus_tag="ROH59_004217"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDX4806626.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
     gene            4346..5740
                     /gene="galP"
                     /locus_tag="ROH59_004218"
     CDS             4346..5740
                     /gene="galP"
                     /locus_tag="ROH59_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HDX4806627.1"
                     /translation="MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            5817..6314
                     /locus_tag="ROH59_004219"
     CDS             5817..6314
                     /locus_tag="ROH59_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HDX4806628.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLIAK"
     gene            6409..7116
                     /gene="endA"
                     /locus_tag="ROH59_004220"
     CDS             6409..7116
                     /gene="endA"
                     /locus_tag="ROH59_004220"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HDX4806629.1"
                     /translation="MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     AAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            7196..7927
                     /gene="rsmE"
                     /locus_tag="ROH59_004221"
     CDS             7196..7927
                     /gene="rsmE"
                     /locus_tag="ROH59_004221"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003853382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDX4806630.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            7940..8890
                     /gene="gshB"
                     /locus_tag="ROH59_004222"
     CDS             7940..8890
                     /gene="gshB"
                     /locus_tag="ROH59_004222"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HDX4806631.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLY
                     LINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQVGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            8999..9562
                     /locus_tag="ROH59_004223"
     CDS             8999..9562
                     /locus_tag="ROH59_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HDX4806632.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLE
                     NLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDN
                     TVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
                     PIADRWREAAKLIGVDILTMPGVAGHA"
     gene            9562..9978
                     /gene="ruvX"
                     /locus_tag="ROH59_004224"
     CDS             9562..9978
                     /gene="ruvX"
                     /locus_tag="ROH59_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDX4806633.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNL
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(10093..11073)
                     /locus_tag="ROH59_004225"
     CDS             complement(10093..11073)
                     /locus_tag="ROH59_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDX4806634.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDAPDV
                     EELLREWLDDDQRTILLENGQLDFAVSLAENQRLRGSAFAQRQGISLALRLLPSHCPQ
                     LEQLGAPPVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMLTFQQSYQQRVGEGRL"
     gene            11091..11795
                     /gene="yggS"
                     /locus_tag="ROH59_004226"
     CDS             11091..11795
                     /gene="yggS"
                     /locus_tag="ROH59_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HDX4806635.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            11813..12379
                     /gene="yggT"
                     /locus_tag="ROH59_004227"
     CDS             11813..12379
                     /gene="yggT"
                     /locus_tag="ROH59_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HDX4806636.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            12376..12666
                     /locus_tag="ROH59_004228"
     CDS             12376..12666
                     /locus_tag="ROH59_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HDX4806637.1"
                     /translation="MSAVTVNDGGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            12674..13267
                     /locus_tag="ROH59_004229"
     CDS             12674..13267
                     /locus_tag="ROH59_004229"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HDX4806638.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTGLPAIADDSGLAVDVLGGAPGIYSARYSGEDATDQKNLQKL
                     LETMKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            13260..14396
                     /gene="hemW"
                     /locus_tag="ROH59_004230"
     CDS             13260..14396
                     /gene="hemW"
                     /locus_tag="ROH59_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HDX4806639.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     NDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEAAPRVEFIQYTGLS
                     EEVIRSQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
     gene            14711..15697
                     /locus_tag="ROH59_004231"
     CDS             14711..15697
                     /locus_tag="ROH59_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HDX4806640.1"
                     /translation="MKMRSFTRSLVCASLLALVSTGVNAAEKVTLKLAHNLERSHVVH
                     QSFEELAKEVKQLSKGNMVIRIYPSSQMGNARETMELLQNGALDMTKGSASDLESFDN
                     IYAIYNLPFLFKDQAHFNKVVFGEVGEEIMDSTKDKGFFALSAYVAGTRSFYAKKPIT
                     KPEDLKGLKIRVQPSPTTIKMIELMGGSPTPISFGEVYTAMQQGVVDGAENNVPSWVQ
                     TRHIEIAKVFSEDEHASIPDFLVISTKTWNKLTPEQQQILETAAKKSEADQQKLWEKI
                     DADTRAQAKAMGGEIVKVDKAPFRAAVQPLFDDFKKDPKQAALLEKFDNAAQ"
     gene            15742..>16137
                     /locus_tag="ROH59_004232"
     CDS             15742..>16137
                     /locus_tag="ROH59_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708723.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDX4806641.1"
                     /translation="MIFNRLKLAVDRVIAAFSVAVMLALVVCVVWQVFSRYVLNQPST
                     LTDELARFLMIWVGLLGAAYTVGAQRHLSIDLFALALNKRKQLLLSIVINVLILGFAG
                     SVIVTGGLKLIDKTLATSQVSAAMQIPMGY"
BASE COUNT         3975 a         4180 c         4080 g         3902 t
ORIGIN      
        1 taggtataac cgtacaaacc tgcctcgaac tcttcaagga actgttgttg cagttcagca
       61 tcaagatcgg ttttcttcac ctgatcgcgg aactgagtta acagcgtttt cggatcgagc
      121 tgcacatatt gcagcatgtc cgccacggta tcgccttcgt cagacagttc tacctctacg
      181 ctaccatcag ggaagacgaa cacgtcaacc gcttcggtat caccgaacag gttgtgcatg
      241 ttgccaagga tctcctgata tgcgccgacc ataaagaaac cgagcatcgg cggattctcc
      301 ggatcgtact ccggcatagg cattgtcgtg gcaataccgt caccatcaat atagtggtcg
      361 atagcaccgt ctgagtcaca ggtaatatcc aacagcacag cgcggcgttc cggcacttga
      421 tccagccctt ccagcggcag aaccgggaac aactggtcga tcccccacgc atccggcatc
      481 gactggaaca gcgagaagtt gacgtacatt ttgtccgcca tacgttcctg cagctcgtcg
      541 ataatcggac gatgagcacg gttttgcgga tccagctgct tttgcacttc atggcacatg
      601 ctcaaataaa gctgctcagc ccatgcgcgt tcttgcaggc taaaggtgcc ggaagagtag
      661 ccgatatgaa tatcgtgcag atccatctgg ctgtcgtgta accattcacg cagagaacgg
      721 cgagttcccg gttcgtgcat ttcctgccag gtttcccaca tgctttgcag ggcgcgcggt
      781 gcgtcttctg caggcgcggt cggcaccgtg tattcgttac gttccacgcc gatgatattc
      841 gacaccagca cggtgtgatg cgcagtcacc gcacgacccg attcggtgat taccgtcgga
      901 tgtggcagac cattttcttc acacgcatca ccaatcgccc agatgatgtt gttggcgtat
      961 tcattgaggc cgtagttcac cgaacagtcg gactgcgaac gggtgccttc atagtccacg
     1021 cccagaccgc cgccgacgtc gaagcactga atattgacgc ccagcttgtg cagctcaaca
     1081 tagaaacgcg cggattcacg aacgcctgtc gcgatatcgc gaatattcgc catctgcgaa
     1141 ccgaggtgga agtgcagcag ttgcaggctg tcgagacgcc cggcttcacg cagggtttca
     1201 accagttgca gtacctgagt cgccgccagg ccgaacttcg atttttcccc gccggaggac
     1261 tgccatttac cggagccctg cgaagccaga cgtgcacgca cgcccagacg aggaacgaca
     1321 ttcagacgtt ctgcttcatc cagcacaatg gcaatttctg acatcttctc aatgaccaga
     1381 tagaccttgt ggcccatctt ctcgccaatt aatgccagac ggatatattc gcggtcctta
     1441 taaccgttgc agacgatgac gctacgggtc atgccagcat gtgccagcac cgccatcaac
     1501 tcagctttgg aaccggcttc caggcccagc ggttcgcccg aatgaatcag ggactcaatc
     1561 acgcggcggt gctggttaac tttgatcgga taaacgagga agtaatcgcc gttatagccg
     1621 taggattccc gcgcacgttt gaacgcggcg ttaatagaac gcaaacggtg ctgcaggatc
     1681 tgcgggaaac agaacagtgc aggcagacgc tggccctgtg cttcacgagt tttcactaac
     1741 tgcgcgagat cgacgcgagc ttccgggacg tccgggtccg ggcacacgct gatgtggccc
     1801 agctcgttaa cgtcatagta gttattgccc caccaggcaa tattgtaagt acgcagcatc
     1861 ttgctggctt cctgggagct cattgcaacc tcctgcatgg agcgtagtac accgtgttcg
     1921 cccgctgacg aaggcaaacc catagacatg tcgtcagaca tagcgaacct caaattattt
     1981 tattaagtgt aaaacagtta acgactatcg cagcctggaa ctgcgataac aacccataag
     2041 cacatggatt ttccagcagt gaatgctgac gctccaactg cgcaaccggt ttctttttca
     2101 taacattatt aagcacataa ccgaacgtaa gtgtgacagt tcggcgaaac cacgagaaaa
     2161 ctcttgtttt tacaagagcg cccttgttca gtcctcagta gctgtaacca gctcttgaat
     2221 cctgagaagc gccgagatgg gtataacatc ggcaggtatg caaagcagag atgcagagtg
     2281 cggggaacga atcttcacca gaacggtgag acaggttaag cagcagacaa cggttcatta
     2341 tttcgtatca cctccacggc cgcctgttaa gacgaaccca caagccaaaa ctctgttttc
     2401 aacccggctg gaagtggcaa cacgaaagaa acgtcgtgtg ctttttattt aagccgcgcg
     2461 ccgcgtttta taccccacaa tggcagaaaa ttgcaaaaga taaatacgca gaatgccagc
     2521 attgtcagga aaaatttcca gccacgtttt taacagaatg agacacgatt caaaaaaaag
     2581 tggaaattgg gtgaagaact gacctaaaat agccatccag atgttaatcc atccataccg
     2641 attaacactc agactgccag tgtttttaac ctgcagagtc gtggtaggat ccgctaccac
     2701 agaaaatcca cacaacagtt tgagctaacc aaattctctt taggtgatat taaatatggc
     2761 aaaacacctt tttacgtccg agtccgtctc tgaagggcat cctgacaaaa ttgctgacca
     2821 aatctctgat gccgttttag acgcgatcct cgaacaggat ccgaaagcac gcgttgcttg
     2881 cgaaacctac gtaaaaaccg gcatggtttt agttggcggc gaaatcacca ccagcgcctg
     2941 ggtagacatc gaagagatca cccgtaacac cgttcgcgaa attggctatg tacattccga
     3001 catgggcttt gacgctaact cctgtgcggt tctgagcgcc atcggcaaac agtctcctga
     3061 catcaaccag ggcgttgacc gtgccgatcc gctggaacag ggcgcgggtg accagggtct
     3121 gatgtttggc tacgcaacca atgaaaccga cgtgctgatg ccagcgccta tcacctatgc
     3181 acaccgtctg gtacagcgtc aggctgaagt gcgtaaaaac ggcactctgc cgtggctgcg
     3241 cccggacgcg aaaagccagg tgactttcca gtatgacgac ggcaaaatcg ttggtatcga
     3301 tgctgtcgtg ctttccactc agcactctga agaaatcgac cagaaatcgc tgcaagaagc
     3361 ggtaatggaa gagatcatca agccgattct gcccgctgaa tggctgactt ctgccaccaa
     3421 attcttcatc aacccgaccg gtcgttttgt tatcggtggc ccgatgggtg actgcggtct
     3481 gactggtcgt aaaatcatcg ttgataccta cggcggcatg gcacgtcacg gtggtggtgc
     3541 attctctggt aaagatccat caaaagtgga ccgttccgca gcgtacgcag cacgttatgt
     3601 cgcgaaaaac atcgttgctg ctggcctggc cgatcgttgt gaaattcagg tttcctacgc
     3661 aatcggcgtg gctgaaccga cctctatcat ggtggaaact ttcggtaccg agaaagtgcc
     3721 ttctgaacaa ctgactctgc tggtacgtga gttctttgac ctgcgtccat acggtctgat
     3781 tcagatgctg gatctgctgc acccaatcta caaagaaacc gcagcatacg gtcactttgg
     3841 tcgcgaacat ttcccgtggg aaaaaaccga caaagcgcag ctgctgcgcg atgctgccgg
     3901 tctgaagtaa tttttcttca cctgctttta aaggccagcc tcgcgctggc ctttttcttt
     3961 tacctcaccg cggtggatag gcgttcatgc cgcatccggc aaaaagctgc ccgcacaata
     4021 acatcattct tcctgaacac gttttaccgc aaattatcat cgctactgaa accgattaca
     4081 ccaaccacgc cagccaaata tttgtaatat tttcatatta ttattcagct ttcacagttg
     4141 ttacatttct tttcagtaaa gtcttaattg cagataacag cgtttaatct atgatgatat
     4201 aactcaatta ttttcatgta cttaaatcat aactaagata aatgttagtg taagcgatta
     4261 cactgatgtg atttgcttca catcttttta cgtcgtactc acctatctta attcacaata
     4321 aaaaataacc atattggagg gcatcatgcc tgacgctaaa aaacaggggc ggtcaaacaa
     4381 ggcaatgacg tttttcgtct gcttccttgc tgctctggcg ggattactct ttggcctgga
     4441 tatcggtgta attgctggcg cactgccgtt tattgcagat gaattccaga ttacttcgca
     4501 cacgcaagaa tgggtcgtaa gctccatgat gttcggtgcg gcagtcggtg cggtgggcag
     4561 cggctggctc tcctttaaac tcgggcgcaa aaagagcctg atgatcggcg caatcctgtt
     4621 tgttgccggt tcactgttct ctgcggctgc gccaaacgtt gaagtactga ttctttcccg
     4681 cgttctgctg gggctggcgg tgggtgtggc ttcttatacc gcaccactgt acctgtcaga
     4741 aattgcgccg gaaaaaattc gcggcagtat gatctcgatg tatcagttga tgatcactat
     4801 tgggatcctc ggtgcttatc tttctgatac cgccttcagc tacaccggtg catggcgctg
     4861 gatgctgggt gtgattatca tcccggcaat tttgctgctg attggtgtct tcttcctgcc
     4921 agacagccca cgttggtttg ctgccaaacg ccgttttgtt gatgccgaac gcgtgctgct
     4981 gcgcctgcgt gacaccagcg cggaagcgaa acgtgaactg gatgaaatcc gtgaaagttt
     5041 gcaggttaaa cagagtggct gggcgctgtt taaagagaac agcaacttcc gccgcgcggt
     5101 gttccttggc gtactgttgc aggtaatgca gcaattcacc gggatgaacg tcatcatgta
     5161 ttacgcgccg aaaatcttcg aactggcggg ttataccaac accaccgagc aaatgtgggg
     5221 gacggtgatt gtcggcctga ccaacgtact tgccaccttt atcgcaatcg gccttgttga
     5281 ccgctgggga cgtaaaccaa cgctaacgct gggcttcctg gtgatggctg ctggcatggg
     5341 cgtactcggt acaatgatgc atatcggtat ccactctccg tcggcgcagt atttcgccat
     5401 cgccatgctg ctgatgttta ttgttggctt tgccatgagt gccggtccgc tgatttgggt
     5461 actgtgctcc gaaattcagc cgctgaaagg ccgcgatttt ggcatcacct gctccaccgc
     5521 caccaactgg attgccaaca tgatcgttgg cgcaaccttc ctgaccatgc tcaacacgct
     5581 gggtaacgcc aacaccttct gggtgtatgc ggctctgaac gtactgttta tcctgctgac
     5641 attgtggctg gtaccggaaa ccaaacacgt ttcgctggaa catattgaac gtaatctgat
     5701 gaaaggtcgt aaactgcgcg aaatcggcgc tcacgattaa tctcctcagg cttcctcccg
     5761 tcgcggagga agccacctct tgcagtcatc ttttcttcgc tctatcctct gccgctatga
     5821 aaacatcccg tctccctatc gccatccaac aggccgttat gcgtcgcctg cgggaaaaac
     5881 tcgcccaggc caacctgaag ctagggcgta actacccgga gccaaaactc tcttacaccc
     5941 agcgcggaac ctccgccgga acagcctggc tggaaagcta tgaaatccgc ctcaatcccg
     6001 ttttgctgtt ggaaaacagt gaagccttta ttgaagaagt ggtgccgcac gaactggcac
     6061 atttgctggt atggaaacat ttcggccgcg tagcgccaca tggcaaagag tggaagtgga
     6121 tgatggaaag cgtgctgggc gttcccgccc gtcgtacgca tcagttcgaa ctgcaatccg
     6181 tgcgtcgcaa caccttcccc taccgctgca agtgccagga gcatcagctt accgtacgcc
     6241 gccataatcg cgtagttcgt ggcgaggccg tctatcgctg tgttcactgc ggtgaacagc
     6301 tgattgcaaa gtaaccacct gaactatcag gaactttcct gatctggctg attgcatacc
     6361 aaaacaactt tcgctacgtt gctggctcgt tttaacacgg agtaagtgat gtaccgttat
     6421 ttgtctattg ctgcggtggt actgagcgca gcattttccg gcccggcgtt ggccgaaggt
     6481 atcaatagtt tttctcaggc gaaagccgcg gcggtaaaag tccacgctga cgcgcccggt
     6541 acgttttatt gcggatgtaa aattaactgg cagggcaaaa aaggcgttgt tgatctgcaa
     6601 tcgtgcggct atcaggtgcg caaaaatgaa aaccgcgcca gccgcgtaga gtgggaacac
     6661 gtcgttcccg cctggcaatt cggtcaccag cgccagtgct ggcaggacgg tggacgtaaa
     6721 aactgcgcta aagatccggt ctatcgcaag atggaaagcg atatgcataa cctgcagccg
     6781 tcagtcggcg aggtgaatgg cgatcgcggc aactttatgt acagccagtg gaatggcggc
     6841 gaaggccagt acggtcaatg cgccatgaag gtcgatttca aagaaaaagc tgccgaacca
     6901 ccagcgcgtg cacgcggtgc cattgcgcgc acctacttct atatgcgtga ccaatacaac
     6961 ctgacactct ctcgccagca aacgcagctg ttcaacgcat ggaacaagat gtatccggtt
     7021 accgactggg agtgcgagcg cgatgaacgc atcgcgaagg tgcagggcaa tcataacccg
     7081 tatgtgcaac gcgcttgcca ggcgcgaaag agctaaccta cactagcggg attctttttg
     7141 ttaaccccta ccccacgcga acaaccgcgt ggggagacga cgcggatttt taactatgcg
     7201 tatcccccgc atttatcatc ctgaaccact gaccagccat tctcatatcg cgctttgcga
     7261 agatgctgcc aaccatatcg ggcgcgtact gcgcatgggg ccggggcagg cgttgcaatt
     7321 gtttgacggc agcaaccagg tctttgacgc cgaaattacc agcgccagca aaaaaagcgt
     7381 ggaagtgaag gtgttggaag gacagatcga cgatcgcgaa tctccgctgc atattcacct
     7441 cggtcaggtg atgtcgcgtg gtgaaaaaat ggaatttact atccagaaat cgatcgaact
     7501 cggtgtaagc ctcattacgc cacttttttc tgagcgctgc ggcgttaaac tggatagtga
     7561 acgtctgaac aagaagctcc agcagtggca gaagattgca attgctgcct gtgagcagtg
     7621 tggtcgtaac cgggtgccgg aaatccgtcc agcgatggat ctggaagcct ggtgtgcaga
     7681 gcaggatgaa ggactgaaac tgaatcttca cccgcgcgcc agtaacagca tcaatacgtt
     7741 gccgttaccg gttgaacgcg tccgcctgct gattggcccg gaaggcggtt tatcggcaga
     7801 tgaaattgcc atgactgccc gctatcaatt tactgatatc ctgttgggac ctcgcgtttt
     7861 gcgtacagag acaactgcgc tcaccgccat taccgcgcta caagtacgat ttggcgattt
     7921 gggctaacgg agaagaataa tgatcaagct cggcatcgtg atggacccca tcgcaaacat
     7981 caacatcaag aaagattcca gtttcgctat gttgctggaa gcacagcgtc gtggttacga
     8041 acttcactat atggagatgg gcgatctgta tctgatcaat ggcgaagccc gcgcccatac
     8101 ccgcacgctg aacgtgaagc agaactacga agagtggttt tcgttcgtcg gtgaacagga
     8161 tctgccgctg gccgatctcg acgtgatcct gatgcgtaaa gacccgccgt ttgataccga
     8221 gtttatctac gcgacctata ttctggaacg tgccgaagag aaagggacgc tgatcgttaa
     8281 caagccgcag agcctgcgcg actgtaacga gaaactgttt actgcctggt tctctgactt
     8341 aacgccagaa acgctggtta cgcgcaataa agcgcagcta aaagcgttct gggagaaaca
     8401 cagcgacatc attcttaagc cactggacgg tatgggcggc gcgtcgattt tccgcgtgaa
     8461 agaaggcgat ccaaacctcg gcgtgattgc cgaaaccctg actgagcatg gcactcgcta
     8521 ctgcatggcg caaaattacc tgccagccat taaagatggc gacaaacgcg tgctggtggt
     8581 agatggcgag ccggtaccgt actgcctggc gcgtattccg caggggggcg aaacccgtgg
     8641 caatctggct gccggtggtc gcggtgaacc tcgtccgctg acggaaagtg actggaaaat
     8701 cgcccgtcag gtcgggccga cgctgaaaga aaaagggctg atttttgttg gtctggatat
     8761 catcggcgac cgtctgactg aaattaacgt caccagccca acctgtattc gtgagattga
     8821 agcagagttt ccggtgtcga tcaccggaat gttaatggat gccatcgaag cacgtttaca
     8881 gcagcagtaa cccaccttag cgagaaggat ctcgttgaga ctctgagtga cagcgccctt
     8941 ctttccacgc atactgggcg ctgttgcttt tttgaaccag gaaacagaac ctctgacaat
     9001 gaatttacag catcactttc ttattgccat gcctgctctc caggatccga ttttccgtcg
     9061 ttccgtggtc tacatttgcg aacataatac caatggtgca atggggatca tcgtcaacaa
     9121 gccgctggaa aatctcaaaa ttgaagggat tctggaaaag ctgaagatca cgccggagcc
     9181 gcgtgatgaa tcaatccgtc tggataaacc ggttatgctc ggcggccctc tggctgaaga
     9241 tcgcgggttt attttgcata ctccgccctc caattttgct tccagcattc gcatttcaga
     9301 caacacggtg atgaccactt cccgcgatgt gctggaaacg ctcggcaccg ataaacaacc
     9361 gtctgacgta ttggtggctc tgggctatgc ctcctgggag aaaggtcaac tggaacaaga
     9421 aattctcgat aacgcgtggc taacggcccc ggcggatctg aatattctgt tcaaaacacc
     9481 gattgccgac cgctggcgcg aggcggcaaa actgattggt gtggatattc tcaccatgcc
     9541 tggtgtggca gggcacgcct gatgagtgga accttactcg ccttcgactt cggtaccaaa
     9601 agcattggtg tagcggtcgg ccaacgcatt accggcaccg ctcgcccatt gcctgcaatt
     9661 aaagcacagg acggtacgcc ggactggaac ctcatcgaac gtttactgaa agagtggcag
     9721 ccggacgaaa tcatcgtcgg tttgccgctg aatatggacg gcaccgagca accattgact
     9781 gccagagcgc gtaaatttgc caaccgtatt catggccgtt tcggtgttga agtaaagctc
     9841 catgacgagc gtcttagcac cgtggaggca cgttccggtc tgtttgaaca gggcggctat
     9901 cgggcgctca acaaaggcaa agttgactct gcctctgcgg ttatcattct cgaaagttat
     9961 ttcgagcagg gatattaagg cgatttacgt catcgctcct tattgccgga tgcggcgtga
    10021 atgactacgt ttgtaggcct gataagcgta gcgcatcagg catatttact aaaataatca
    10081 atcactttag cctcacaaac gcccttcccc cacccgctgc tgataactct gctgaaacgt
    10141 taacatcccc acctgctgcc cggtttgaat aacatgcggt aactggtggg ttttcccttc
    10201 gcgaatcaaa ttccccaccg cgggagtgtt aatcagtaat tcaaacagcg ccacgcgtcc
    10261 ttcctgttta tccacttcca gcttttgtga caacactgcc cgtaaactcc ccgccagttg
    10321 attacgtacg ggatcttttt cctgcgccgg aaatgaatcc accagccgct caactgcctg
    10381 cgccgcacca cgcgtatgta atgttgccag caccaaatgc ccggtttctg ccgccgtcag
    10441 tgccagacgg attgtctcgc tgtcacgcag ctctccgagc aatatcacat cgggatcttc
    10501 ccgcaatgcg gcacgcaatc ccgatgcgaa cgtcatacag tgcaaaccaa tttcccgctg
    10561 ctggatcaaa catcgctggc tggcatagag atattcaaca ggatcttcca gcgtcagaat
    10621 atgcgcatcg gcatgttgat tgagatagcc aaccatcgcc gccagcgtgg tagatttgcc
    10681 gctccccgtc gcccccgtca ccagaatcag gccattctcg ctcttgagta attccggcaa
    10741 taccggtggc gcaccaagct gttcgagctg tggacagtgc gaaggtaaca accgtaatgc
    10801 cagagaaata ccttgccgtt gcgcgaacgc actgccacgc aaccgctggt tttccgccag
    10861 cgacacagca aaatccaact gaccattctc cagcaatatt gtccgctgat cgtcatccag
    10921 ccactcccgc agtagctctt cgacgtccgg cgcatcaaac ggcgcagctt ccattcgccc
    10981 gcgaatacgc catcgtgcgg gccaggcgct gcacaggtgt agatccgaga cgttatgctt
    11041 tacactaagg gccacaattt cttccatatt catactaaga tcctcggaaa atgaacgata
    11101 ttgcgcataa cctggcacag gtccgggaca aaatctcagc ggctgcaacg cgttgcggcc
    11161 gttctccaga agaaattacg ctgcttgcag tcagtaaaac aaaacctgcg agcgccatcg
    11221 cagaagccat tgatgccggg cagcgtcaat ttggtgaaaa ctacgttcag gaaggggtag
    11281 ataaaattcg ccactttcag gaactgggcg taacaggatt agaatggcat tttattggcc
    11341 cgttgcagtc taataaaagc cgcctggtgg cagagcattt cgactggtgt cataccatcg
    11401 accgtttgcg cattgctacc cgcctcaacg atcagcgccc ggcagaactt ccccctctta
    11461 acgtactgat tcaaattaat attagtgacg aaaacagtaa gtccgggatt caactggcag
    11521 aactggacga gctggcagct gcggtcgctg aactaccgcg tttacgtctg cgcgggctga
    11581 tggcaatccc tgcacctgag tcagaatatg taaggcagtt tgaagttgca cgccaaatgg
    11641 ctgtagcatt tgccggactg aaaacgcgct acccgcatat cgacacgctc tctctgggaa
    11701 tgtcggacga tatggaagcc gccattgcgg caggtagcac gatggttcgt atcggcactg
    11761 caatttttgg tgcgcgtgat tactctaaaa aataaggaat taaaggaacg ccatgaatac
    11821 gttgactttc ctgctttcaa cggtcattga gctgtatacc atggtgctgt tattacgcat
    11881 ctggatgcag tgggctcatt gtgattttta caaccccttc tcacagtttg tagtgaaggt
    11941 aacgcagcca attatcgggc cactgcgccg cgttattccg gcaatggggc ccattgacag
    12001 cgcctcactg ctggttgcgt acattctcag tttcatcaaa gccatcgtgc tgtttaaagt
    12061 ggtgaccttc ctgccaatca tctggattgc cggtttactg attctgctga aaaccatcgg
    12121 cctgctgatt ttctgggtcc tgctggtgat ggcgattatg agctgggtaa gccaggggcg
    12181 tagcccgatt gaatacgtgc tgattcagct ggccgatccg ctgctgcgcc cgattcgccg
    12241 cctgctaccg gcaatgggtg ggattgattt ctcgccgatg atcctcgttc tgctgctgta
    12301 tgtcatcaat atgggtgtcg cagaagtctt gcaggcgacc ggaaatatgc tgctgccggg
    12361 gctgtggatg gcgttatgag tgccgtaaca gtgaatgatg gcggtctggt tttacggctc
    12421 tatattcagc cgaaagccag ccgtgattct attgtcggtt tacatggcga cgaggtaaaa
    12481 gtcgccatta ccgcgccgcc ggttgacggc caggccaaca gccatctggt gaagtttctc
    12541 ggtaagcaat tccgggttgc caaaagccag gtggtgattg aaaaaggcga acttggccgc
    12601 cacaaacaaa ttaaaatcat taatccgcaa caaatcccgc cagaaatcgc ggcgttaatt
    12661 aattaggtat cctatgcaaa aagttgtcct cgcaaccggc aatgccggta aagtgcgtga
    12721 gctggcgtcg ctgcttagcg acttcggtct tgatatcgtg gcccaaacag acctcggtgt
    12781 agattccgct gaagaaactg gcctgacctt tatcgaaaac gcgattctga aagcgcgcca
    12841 tgcggcaaaa gtgaccggtt taccggcaat tgccgacgac tccggtctgg cggtagatgt
    12901 acttggcggt gcaccgggga tttactccgc gcgttattcc ggtgaagacg cgaccgatca
    12961 aaagaatctg caaaaactgc tggaaacaat gaaagacgta ccggacgacc aacgtcaggc
    13021 gcgtttccac tgcgtgctgg tatatctgcg tcacgcggaa gatcccactc cgctggtgtg
    13081 ccacggtagc tggccgggcg tgattactcg tgaaccagcg ggcactggtg gctttggtta
    13141 tgatccaatc ttctttgttc cttccgaagg gaaaaccgct gccgaactga cccgcgaaga
    13201 aaagagcgcc atttcccacc gtggtcaggc attgaaactg ctgctggacg ctttacgtaa
    13261 tggttaaatt accgccgctg agtctctaca ttcacatccc gtggtgcgtg cagaaatgcc
    13321 cgtactgcga tttcaactct cacgcgttga aaggagaagt gccgcacgac gattatgttc
    13381 agcatctgct taacgatctg gacaacgatg tggcttacgc tcagggccgt gaagtgcaga
    13441 caatctttat tggcggtggt acgccgagcc tgctttccgg cccggcgatg caaacgctgc
    13501 tggacggcgt gcgtgcgcgt ttgccgctgg cagcggatgc agaaattact atggaagcga
    13561 acccaggcac ggtagaagcg gatcgctttg tcgattatca gcgtgctggt gtgaaccgca
    13621 tctctattgg tgtgcagagt tttagcgaag aaaagctgaa acgactcggg cgtattcatg
    13681 gcccgcaaga agcgaaacga gcggcaaagc tggcgagcgg tttagggtta cgtagtttta
    13741 accttgattt gatgcatggg ctgccggatc aatcactgga agaggcgcta ggcgatctgc
    13801 gccaggctat tgaactgaat ccgccacatc tttcctggta tcaactgacc atcgaaccta
    13861 atacgctgtt tggctcgcgc cctcctgtac tgccggacga tgacgcgctg tgggatattt
    13921 tcgaacaggg gcatcagtta ttaaccgcag cgggctatca gcagtatgaa acatccgctt
    13981 acgccaaacc cggttatcag tgccagcaca atctcaacta ctggcgattt ggcgactaca
    14041 tcggtattgg ctgcggcgcg cacggcaaag tgaccttccc ggatgggcgc attctgcgta
    14101 ccaccaaaac gcgtcatccg cgtggtttta tgcagggaag atatctggaa agccagcgtg
    14161 atgtcgaagc tgcagataaa ccgtttgagt tctttatgaa tcgcttccgt ctgctggaag
    14221 ccgcgccgcg cgtggagttt atccaatata ctggcctttc tgaagaagtt attcgctctc
    14281 agttagacga ggccatcgct caaggttatc tcacagaatg tgcggattac tggcagataa
    14341 ccgagcatgg taaattattc ttaaactcac ttcttgaatt attcctcgct gagtaatcat
    14401 taatgcgcct gcgggcgcat taatcacttc ttttaacccc cccgttaatt aacttcggca
    14461 aaaatatatt tcttactgaa taaatatcga cgatatttat tatatatatt tagtgaatat
    14521 ttactcatca tttattgatt ataaatatgt acaacctggc gcacaaaatt aatatttaat
    14581 ttctgacttt atttcaagtt gtgataaaca tagacaagtt gtcagacagg ttaaccaatt
    14641 tgtcgcacaa agcactgata agcacaatta gatatcaacc aatttccatt cttcaacagg
    14701 gagttttttt atgaaaatga ggtcatttac ccgctcatta gtctgcgcat ccttgctggc
    14761 tctggttagc actggcgtaa acgccgcaga aaaagtgacg ttaaagttag cacacaacct
    14821 ggaaagaagt catgttgtac atcagagttt tgaagagctg gcgaaagagg taaaacagct
    14881 gtcaaaaggt aatatggtga tccgtattta tcccagcagc cagatgggta atgcgcgaga
    14941 aactatggag ttgttgcaaa atggtgcact ggatatgacc aaaggttccg ccagtgatct
    15001 ggagtctttt gataatattt atgctatcta taatttgccg ttcttattta aagatcaggc
    15061 gcacttcaac aaagtggttt ttggtgaagt tggtgaagaa attatggatt caacaaaaga
    15121 taaaggcttt tttgctttat cagcttatgt agcgggtaca cgcagtttct atgcgaaaaa
    15181 accgattact aagccagaag atcttaaagg gctgaaaatt cgtgttcagc caagcccgac
    15241 caccatcaaa atgattgaac tgatgggtgg ctcacccact ccaatttcat ttggcgaagt
    15301 ttatactgcg atgcagcaag gtgtagtaga tggcgcagaa aataacgtgc cttcctgggt
    15361 gcagactaga catatcgaaa ttgccaaagt cttttctgaa gatgaacatg cctcaattcc
    15421 tgactttttg gttatctcca ccaaaacatg gaataaatta accccagaac agcaacaaat
    15481 cctcgaaaca gcggcgaaga aatccgaagc tgatcaacaa aaattgtggg aaaaaattga
    15541 cgctgacaca cgtgctcagg cgaaagctat gggtggtgaa atcgttaagg ttgataaagc
    15601 cccattccgt gccgcagttc aacctctgtt tgacgacttc aaaaaagatc caaaacaagc
    15661 tgctttgtta gagaaattcg acaacgctgc tcaataatat ttcgggccag tctctggccc
    15721 tgattttcca ggatgcttac aatgatattt aaccgcctga aacttgcggt agaccgcgtc
    15781 attgccgcgt tttctgtcgc cgtaatgctt gctctggttg tatgcgtagt ctggcaagta
    15841 tttagccgct acgtacttaa ccagccaagt acattaaccg atgagctggc acgctttttg
    15901 atgatctggg taggattatt aggtgctgca tataccgtcg gcgcgcagag acatctctct
    15961 atcgatttat ttgctctcgc cctgaataag cgcaagcaat tacttcttag tatagtcatt
    16021 aacgttctta ttttaggttt tgccggttcg gttattgtga ctggtggcct gaaattaatt
    16081 gataaaacac tggcaacatc acaggtatct gccgcgatgc aaataccgat gggatac
//
LOCUS       DAPOXO010000103        15788 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPOXO010000103 DAPOXO010000000
VERSION     DAPOXO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15788
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.103"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1358
                     /gene="chuA"
                     /locus_tag="ROH59_004233"
                     /gene_synonym="shuA"
     CDS             <1..1358
                     /gene="chuA"
                     /locus_tag="ROH59_004233"
                     /gene_synonym="shuA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TonB-dependent heme/hemoglobin receptor
                     ChuA/ShuA"
                     /protein_id="HDX4806642.1"
                     /translation="SNGETAPNDESINNMLAKGTWQIDSAQSLSGLVRYYNNDAREPK
                     NPQTVEASDSSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTGS
                     SGEYREQITKGARLENRSTLFADSFASHLLTYGGEYYRQEQHPGGATTGFPQAKIDFS
                     SGWLQDEITLRDLPITLLGGTRYDSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLF
                     GSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLRFDDLM
                     LSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSL
                     DVAYNRTRGKDTDTGEYISSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSSY
                     SKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYWSPQGIPQDGRNGKIFVSYQ
                     W"
     gene            1407..2435
                     /gene="chuS"
                     /locus_tag="ROH59_004234"
     CDS             1407..2435
                     /gene="chuS"
                     /locus_tag="ROH59_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hematinate-forming heme oxygenase ChuS"
                     /protein_id="HDX4806643.1"
                     /translation="MNHYTRWLELKEQNPGKYARDIAGLMNISEAELAFARVTHDAWR
                     MRGDIREILAALESVGETKCICRNEYAVHEQVGAFTNQHLNGHAGLILNPRALDLRLF
                     LNQWASVFHIKENTARGERQSIQFFDHQGDALLKVYATDNTDMAAWSELLARFITDEN
                     TPLELKAVDAPVVQTRADASVVEQEWRAMTDVHQFFTLLKRHNLTRQQAFNLVADDLA
                     CKVSNSALAQILESAQQDGNEIMVFVGNRGCVQIFTGVVEKVVPMKGWLNIFNPTFTL
                     HLLEESIAEAWVTRKPTSDGHVTSLELFAHDGTQIAQLYGQRTEGEQEQAQWRKQIAS
                     LIPEGVTA"
     gene            complement(2492..3022)
                     /locus_tag="ROH59_004235"
     CDS             complement(2492..3022)
                     /locus_tag="ROH59_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4806644.1"
                     /translation="MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVI
                     IDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTIAIIDFVALI
                     NGSYCSVPEADVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNL
                     KRINELVRHQHINYLV"
     gene            complement(3175..3741)
                     /gene="slp"
                     /locus_tag="ROH59_004236"
     CDS             complement(3175..3741)
                     /gene="slp"
                     /locus_tag="ROH59_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HDX4806645.1"
                     /translation="MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQ
                     PGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFL
                     DPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYG
                     YGAFWPEPGWGAPYYTNAVSQVTPELVK"
     gene            complement(3931..4310)
                     /locus_tag="ROH59_004237"
                     /pseudo
     CDS             complement(3931..4310)
                     /locus_tag="ROH59_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709288.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4927..5352)
                     /gene="arsC"
                     /locus_tag="ROH59_004238"
     CDS             complement(4927..5352)
                     /gene="arsC"
                     /locus_tag="ROH59_004238"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HDX4806646.1"
                     /translation="MSNITIYHNPACGTSRNALEMIRNSGTEPTIIYYLETPPTRDEL
                     VKLIADMGITVRALLRKNVEPYEELGLAEDKFTHDQLIDFMLQHPILINRPIVVTPQG
                     TRLCRPSEVVLEILPDAQKGAFTKEDGEKVVDEAGNRLK"
     gene            5687..5770
                     /locus_tag="ROH59_004239"
     CDS             5687..5770
                     /locus_tag="ROH59_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Damage inducible protein"
                     /protein_id="HDX4806647.1"
                     /translation="MIDKAIIVLGALIAQLELIRFLLQLLN"
     gene            complement(5824..7176)
                     /gene="gorA"
                     /locus_tag="ROH59_004240"
     CDS             complement(5824..7176)
                     /gene="gorA"
                     /locus_tag="ROH59_004240"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDX4806648.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTIEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNVEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCIGPEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(7248..8090)
                     /gene="rlmJ"
                     /locus_tag="ROH59_004241"
     CDS             complement(7248..8090)
                     /gene="rlmJ"
                     /locus_tag="ROH59_004241"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase"
                     /protein_id="HDX4806649.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDYPLLRSEFQKDNRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            8293..10335
                     /gene="prlC"
                     /locus_tag="ROH59_004242"
     CDS             8293..10335
                     /gene="prlC"
                     /locus_tag="ROH59_004242"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HDX4806650.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMELFKRFRGREPQLDAMLEHYGIKG"
     gene            10343..11095
                     /gene="rsmJ"
                     /locus_tag="ROH59_004243"
     CDS             10343..11095
                     /gene="rsmJ"
                     /locus_tag="ROH59_004243"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709277.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HDX4806651.1"
                     /translation="MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPAQLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(11144..12613)
                     /gene="dtpB"
                     /locus_tag="ROH59_004244"
     CDS             complement(11144..12613)
                     /gene="dtpB"
                     /locus_tag="ROH59_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HDX4806652.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADKFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     QLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(12930..13364)
                     /gene="uspA"
                     /locus_tag="ROH59_004245"
     CDS             complement(12930..13364)
                     /gene="uspA"
                     /locus_tag="ROH59_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HDX4806653.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            13755..14090
                     /gene="uspB"
                     /locus_tag="ROH59_004246"
     CDS             13755..14090
                     /gene="uspB"
                     /locus_tag="ROH59_004246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HDX4806654.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            complement(14161..15660)
                     /gene="pitA"
                     /locus_tag="ROH59_004247"
     CDS             complement(14161..15660)
                     /gene="pitA"
                     /locus_tag="ROH59_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HDX4806655.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
BASE COUNT         4056 a         3832 c         4035 g         3865 t
ORIGIN      
        1 agagcaatgg tgaaaccgcg ccgaatgacg aatccattaa taacatgctg gcgaaaggga
       61 cctggcaaat tgattcagcc cagtctctga gcggtttagt gcgttactac aacaacgacg
      121 cgcgtgaacc aaaaaatccg cagactgttg aagcttctga tagcagcaac ccgatggtcg
      181 atcgttcaac aattcaacgc gatgcgcagc tttcttataa actcgccccg cagggtaacg
      241 actggttaaa tgcagatgca aaaatatact ggtcggaagt ccgtattaat gcgcaaaaca
      301 cggggagttc aggcgagtat cgtgaacaga taacaaaagg agcaaggctg gagaaccgtt
      361 ccactctatt tgccgacagt ttcgcttctc acttactgac atatggcggt gagtattatc
      421 gtcaggaaca acatccgggt ggcgcgacga cgggcttccc gcaagcaaaa atcgatttta
      481 gctctggctg gctacaagat gagatcacct tacgcgatct gccgattacc ctgcttggcg
      541 gaacccgcta tgacagttat cgcggtagca gcgacggcta caaagatgtt gatgccgaca
      601 aatggtcatc tcgtgcgggg atgactatca acccgaccaa ctggctgatg ttatttggct
      661 catatgctca ggcattccgc gccccgacga tgggcgaaat gtataatgat tctaaacact
      721 tctcgattgg tcgcttctat accaactatt gggtgccaaa cccgaactta cgtccggaaa
      781 ctaacgaaac tcaggagtac ggttttgggc tacgttttga tgacctgatg ttgtccaatg
      841 atgctctgga atttaaagcc agctactttg ataccaaagc gaaagattat atctccacga
      901 ccgtcgattt cgcggcggcg acaactatgt cgtataacgt cccgaacgcc aaaatctggg
      961 gctgggatgt gatgacgaaa tataccactg atctgtttag ccttgatgtg gcctataacc
     1021 gtacccgcgg caaagacacc gataccgggg aatatatctc cagcattaac ccggataccg
     1081 ttaccagtac cctgaatatt ccgatcgctc acagtggctt ctctgttggt tgggtcggta
     1141 cgtttgccga tcgctcaaca catatcagca gcagctacag caaacaacct ggctatggtg
     1201 tgaatgattt ctacgtcagt tatcaaggac aacaggcgct caaaggcatg accactactc
     1261 tggtattggg caacgccttc gataaagagt actggtcgcc gcaaggcatc ccacaggatg
     1321 gtcgtaacgg aaaaattttc gtgagttatc aatggtaatc atctgccccg atatttcggg
     1381 gcatttatct ggaaggaaga gagacaatga accactacac acgctggctt gagttaaaag
     1441 aacaaaatcc cggaaagtac gcgcgtgaca tcgcaggttt aatgaatatc agcgaagcag
     1501 aactggcatt tgcgcgcgtc acgcacgacg cgtggcggat gcgcggcgat attcgtgaaa
     1561 ttctggcggc gctcgaaagt gttggcgaaa ccaaatgtat ttgccgtaat gaatatgcag
     1621 tccatgagca agttggtgcg ttcacaaacc agcatttgaa cggacatgcc ggattgatcc
     1681 tcaatccgcg cgcgctggat ttacgtctgt ttctcaatca atgggccagt gttttccaca
     1741 tcaaagaaaa cacggcccgt ggcgaacgcc agagtattca gttctttgat catcagggcg
     1801 atgcattact aaaagtttat gccaccgaca ataccgatat ggcggcatgg agtgagcttc
     1861 tggcacggtt tatcaccgat gagaatacgc cgcttgagtt aaaagccgtt gatgcgccag
     1921 ttgttcaaac gcgagccgat gccagtgtgg tcgagcaaga gtggcgggcg atgaccgacg
     1981 ttcatcagtt ttttacgttg ctcaagcgtc acaatctgac gcgccaacag gcgttcaatc
     2041 tggtggcaga cgatttggcc tgcaaagtat ccaacagtgc gttggcgcaa attcttgaat
     2101 ctgcacagca ggatggcaat gaaatcatgg tgtttgttgg caaccgtggc tgcgtacaga
     2161 ttttcaccgg tgtggtagaa aaagtggtgc caatgaaagg ttggctgaat attttcaacc
     2221 cgacgtttac tcttcatcta ttagaagaga gcattgctga agcctgggtt acccgtaaac
     2281 cgaccagcga tggtcacgta accagtctgg aattgtttgc ccatgatggt acgcagatag
     2341 cgcaacttta tggtcaacgt acagaaggtg aacaggagca agcgcaatgg cgtaagcaaa
     2401 ttgcttcgtt gataccggaa ggcgttactg cataacgtat aattaacggg aggtctggct
     2461 gttgctgggc ctctttatat tgatcaatcg ttcacaccag ataattaata tgctgatggc
     2521 gtaccagctc attgatccgc ttaagattga ggatcatcat gatattgtgt ttatggcagt
     2581 agaacgtttt tagcgatatt ttcagtttct ccagaatatc ttccgttgtc atttgattcg
     2641 caatacagct cagaacctga tgctgcttgc gcgagaggga cacatccgct tcaggcacag
     2701 agcagtaact gccattgatg agtgcgacaa agtcgatgat ggcgatagtt cgcggaacaa
     2761 aggtcaccgg tactttcccc aggcagcgtt taatattaaa gggggagaaa ataattacat
     2821 ggacaggttt taatcgttca atttgagtga gaaaattaga atgaaataca ttattcatta
     2881 atgtatcaat aatgacgaag gcattctgat gcaacattac gtcgatctct tcttcgttct
     2941 gtatatgaac gacattacct ttactcagaa tgtttttcat cgcggtgaaa aacatcgtat
     3001 ccctggtaat tataagaaac ataaccgact cctggtacgg acattaactt tataatcagt
     3061 ttgccaaagg taattaacag gacagggctt ataataatag ttagcttact gtgtattaat
     3121 ttgatgtaat gcatgatgca gatgctgaga aagcatctgc atctttcggt ggtgttattt
     3181 gaccagctca ggtgttacct gactcaccgc attggtgtag taaggagccc cccagcccgg
     3241 ttccggccag aatgcaccat agccgtaatc ccacaggtta taggtggtat taaccacttc
     3301 tctcaaatgc cacacctgga tgccctgcat attcacttcg aggaagttat acgggacttt
     3361 attgataaag ccaggttgtt caccctgaat ggtaccgagg atggtaacaa agtgattacg
     3421 atagttcact ggatcaagga agccgctttg tctggcgagc agtcggccct gatagttggc
     3481 ttcaatatca ggcttcgcat agctatccaa cggtaataca gcgatttcta acaacgtatc
     3541 cgttttgcca ttgataacgt tgataacctt cccaccaaag cgcgcttgtt gaccaacata
     3601 taaccccggc tggttatgaa cagcaacaaa acttttttga atatcaggtt ggttattgcc
     3661 tttgatattt tgcggaattg aactacatgc ggcaagcaaa aatgaaaggc tgaggatgag
     3721 tgcacctttt gtcatgttca tgttactatc cttatcaaca aatattaaaa ccataataga
     3781 tatttcttta tagttttcat ctgattctga ggcgatatgc ctgatagtaa cgtaaacctg
     3841 tctgatgttt atatctcttc tgtttagttg agctcagtta atttttgggc gtggcatgag
     3901 tatccattgt tccataattt atattaggag gtttttaatc ttttcgtgtc taatgttatt
     3961 tatctgatta agtattgatt gtgtcttttg cggaagtggt gtcgagctta tcgtttcaat
     4021 gttattaata agacttacaa gttgagcctc aactttgagt agtctgcatt tgtatatgtg
     4081 gtgttcgtat ggcacgcatt aatttgttgg cgttgttgtt gcgctaaatc aaattgttta
     4141 gaggtgtatc cttctccaga gaatggggaa ttaatgggtt gttgttcttc ccggttatca
     4201 caaggccact tcggtgtgtc tggcgtttta acattatcgg tatttgttgt gcagttataa
     4261 atatcaccgt tatatgtatt tattacacct ggggtaaagt caattgacat aacattcctt
     4321 attcatcatt tgttttatgc taagatttta aaattggata attagaacag gaatggattt
     4381 tcttctacat acagtaaata taatgcgtca tatcttcctg atataattac ctttgacttc
     4441 tcttttattt ccatctggta atatttgagt gcaaaaaaag gcaataataa tatcgcaaaa
     4501 gaaaacgtta acaactatcg aaaatgctcg ttttaaaaag gtatgatgtt ctctgatagt
     4561 gtgtgaagtg atatttttgt gatgttttag atatgtaata ataaaatggg ttaacgtatg
     4621 ttgaaattat ttattgtgca aaccactgat agatcataat ccagtacatc tttacagtgc
     4681 tgcactgtat cgctgataac taagcagctc actgatacac catgctggac gcgataattg
     4741 gaatctcacg cagggagtac tgtgtaaata gcaaaatcgc ctgatgcgct acgactgtca
     4801 ggcctacaaa taacatacaa ttcatcgaat tatcataacg ttgtaggtcg gataagacgc
     4861 gtcagcgtcg catccgacat aaataaagcg catttttcta acaacctgtg ggggaatata
     4921 gccgctttat ttcaggcgat tacccgcctc atcaaccact ttctcgccat cttccttggt
     4981 gaacgcgcct ttttgcgcat ctggcagaat ttccagcacg acttctgaag ggcggcacag
     5041 gcgagttccc tgtggcgtca ccacaatcgg gcgattaatc agaatcgggt gctgaagcat
     5101 aaagtcgatt aactgatcgt gagtaaattt atcttctgca aggcccagtt cctcatacgg
     5161 ctcgacgttt ttacgcagca acgcgcgtac ggtaatcccc atatcggcaa tgagttttac
     5221 cagctcatcg cgcgtcggtg gtgtttccag ataatagata atggtcggtt ctgtaccgct
     5281 gttgcggatc atctccagcg cattacgcga cgtaccgcag gccgggttgt gataaatggt
     5341 aatgttgctc atatcagtat ctcattacaa tgtgaaagag aggtgtagcg ccagcgccac
     5401 cagcgttaca aaccaaagcg gacaagtcaa aaacacatat ggtttaacga atatgtaagt
     5461 gtagagaaag gtgtaggtgt gaattaagcg ttgggcattc atttgaaagg aggtctgaat
     5521 caggacgtaa aaaaaccgac ttcgcgtcgg tttttttact gttcagccct gagttggtgg
     5581 ctctggctgg agtgagatag cccacatcta acaatgagac atgctccgtg acaggcaatg
     5641 gatgagtaag cggatgcatt ctcactccat cgcatggaga aaacgggtga ttgataaagc
     5701 aatcatcgtt cttggggcgt taattgcgca gctggaactg atccgctttc tgcttcagct
     5761 tctgaactga tagcggaaac gtagctaagg gctaagagca cactactctt agccctttaa
     5821 catttaacgc attgtcacga actcttctgc tgctgtcggg tgaatggcaa ccgtgttgtc
     5881 gaagtctttt ttggttgcac ccatcttcag cgccaccgcg aagccctgca acatttcgtc
     5941 cataccaaaa ccaatgccgt gaataccgac aatcttctct tccggtccaa tgcataccag
     6001 tttcatgcga cacggctggc ggtgagtggt gacggcggta tacatcgcgg tgaaagagga
     6061 tttatacact ttcacctgat cgtcgccgta ctgctcgcgc gcctgcggct ccgttaaacc
     6121 aacagtacca atcggcggat ggctgaagac cacggtcgga atgttgctgt aatccagatg
     6181 ctcatccggc ttgttattaa acaggcgttc agagagacgg cgacctgctg caactgccac
     6241 cggagtcagt tccactgcac ccgtgttatc gcccaccgcg taaatacctt caacgttggt
     6301 gttttgatat ttatcgacga cgatatagcc tttttcgttg gttttaacgc cagcggcttc
     6361 caggttgatg ttgtcattgg caggctcgcg accaatcgcc caaatcaggc aatccaccgt
     6421 ttcactgcga ccatcttcca gctccagcgt caggctgccg tcggcatttt tcaccaccgc
     6481 tttcgggatg gcgttggtat gcaactgtgg gccttcggcg ttcatcactt cgaccagcgt
     6541 ttcagagatc atcgggtcga agctgcgcag cggcgcatgt ttacgcacaa acagatgcgt
     6601 cttcgcaccg aggccgttaa tcacgcccgc cagttcaacg gcgatgtaac ccgcgccaac
     6661 aaccgctacg cgctctggca aagccggaag ggcgaagaag ccatcagaat caataccgta
     6721 ttccacgccc ggaatatccg ggtggctcgg acgaccaccg gtggcgatca gaatatgatc
     6781 ggccgtgatg gtttcgccgt tgacttcaat ggttttggca tcaacgaagc gggcaaagcc
     6841 tttgattaca tcaacgttat ttttaccgag cacgttctca taggaagtat gaatacggtc
     6901 gatataggcg gtacggctgg cgatcaatgt ttcccagttg aatttattga tagtggtatc
     6961 aaagccgtaa tccgggccgt acatatggat cgcttcacgg atttgtgccg cgtgccacat
     7021 cacttttttc ggcacacagc caacatttac gcaggtgccg cccagctctt tggcttcaat
     7081 cagtgcgcat ttctggccgt acatagccgc gcggttgatg gaggcgatac cgccgctgcc
     7141 gccgccgatg gcgatgtaat catagtgttt agtcatgaca tattgtcctt atcgttgatt
     7201 accgcgattg tagcgcgaga cgtaataggt gccagcaatg gctgcaatta ctctggcacg
     7261 atccagctta cggtggcgtg cccggtgcct gctggaacca gtttgctgtg cagccacggc
     7321 agcacgttat tcatctgctg ttccagcttc cacggcgggt taatcacaat catgccggaa
     7381 gcggtcatgc cacggcgatc gctgtctggc agcaccgcca gttcaatttg cagaattttg
     7441 cgaatgccgg tcgcttccag gtcgtggatc atgcgcttaa tctgctggcg cagcaccact
     7501 ggataccaca atgcgtaagt gccagtggcg aaacgtttgt aaccttctgc tatcccgctg
     7561 accaccgcct gatagtcggt tttcatttca tacggcggat cgataaggat taaaccacgg
     7621 cgggaaaccg gcggtagttt ggccttaagc tgctggaaac cgtcggcttt ttcaacgcgc
     7681 gcacgattgt ctttctggaa ttccgaacgt aacaacggat aatcgctcgg gtgcagttca
     7741 gtcagttgca ggctgtcctg ttcacgcagt agctggcgcg caatcaacgg cgaaccgggg
     7801 taataacgca actgcccgct acggttgaag tgttttacca cattgatgta cgcctccagc
     7861 tccgcaggca aatcgtcctg ctgccagata cgggcgatac cttcgagata ttcgccggta
     7921 cgctcggcat gttcgctgcc taactgataa cgcccggccc ctgcgtgggt gtcgagatag
     7981 agaaacggtt tatctttctc tttcagcgac tcgatgatca ggctctgaac ggtatgttta
     8041 aggacgtcgg cgtggttgcc agcgtgaaag ctgtggcgat aactgagcat gggtaaaggt
     8101 gttccggtaa gtaaaaatcg gcccgtattc ggggcgcaca aaagtctatc aggacagtat
     8161 accgaaaaga ggccgccgcc gcgaaagcgt aacgtttctc attgaaattc actacactta
     8221 accccatgct acaaacatta tgtaaagcgc ctgttgagcg cttccttaac ctctttaacc
     8281 aggactgcgc taatgacgaa tccgttactg actccctttg aattgcctcc gttttctaaa
     8341 attctcccgg aacatgtcgt tccagccgtg actaaggcgc tgaacgactg ccgcgaaaat
     8401 gtggagcgcg tagtagcgca aggggcaccg tacacctggg aaaatctctg ccagccgttg
     8461 gcggaagtgg acgatgtgct ggggcgtatc ttctccccgg tcagccatct gaactcggtg
     8521 aaaaatagcc cggaactgcg tgaagcgtac gaacaaaccc tgccgctgct gtcagaatac
     8581 agcacctggg taggacaaca tgaagggctg tataaagcat atcgcgacct gcgcgatggc
     8641 gatcattacg ccacgctgaa cacggcgcag aaaaaagcgg ttgataacgc actgcgcgac
     8701 ttcgaactct ctggcatcgg tctgccgaaa gagaaacagc agcgttacgg cgaaattgcc
     8761 actcgtcttt ctgaactggg caatcagtac agcaacaacg tcctcgatgc gacgatgggc
     8821 tggaccaaac tcgttaccga cgaagcggag ctggcgggga tgccagaaag cgcgctggct
     8881 gcggcaaaag cccaggccga agcgaaagag ctggaaggtt atttgctgac gctggatatc
     8941 ccaagctacc tgccggtaat gacctactgc gacaaccagg ccctgcgtga agagatgtat
     9001 cgtgcttata gcactcgtgc ttccgatcaa ggtccgaacg ccggtaagtg ggataacagc
     9061 aaggtgatgg aagagatcct cgcgctgcgt cacgaactgg cgcaactgct gggctttgaa
     9121 aactacgcct tcaaatcact tgccactaaa atggcagaaa acccgcagca ggtgctggat
     9181 ttcttaaccg atctggcaaa acgcgcgcgc ccgcaaggcg aaaaagagct ggcacaactg
     9241 cgcgccttcg ccaaagccga atttggcgtc gatgagttgc aaccgtggga tatcgcttac
     9301 tacagcgaaa aacagaaaca gcacctctac agcatcagcg atgaacaact gcgtccgtac
     9361 ttcccggaaa acaaagcggt taacggcttg tttgaagtgg tgaaacgtat ttacggcatc
     9421 accgctaaag agcgtaaaga tgttgatgtc tggcatccgg atgtacgttt cttcgaacta
     9481 tatgacgaga acaacgaact gcgcggtagc ttctacctcg acctgtatgc ccgtgaaaac
     9541 aagcgcggcg gggcgtggat ggatgactgc gtaggccaga tgcgtaaagc cgacggttcg
     9601 ctgcaaaaac cggtcgcgta tctgacctgc aacttcaacc gcccggtaaa tggtaaaccg
     9661 gcgctgttta cccatgacga agtgatcacc ctgttccacg agttcggtca cggcctgcac
     9721 catatgctga cccgcattga aaccgctggt gtttccggga tcagtggggt gccgtgggat
     9781 gcggtcgaac tgccgagcca gtttatggaa aactggtgct gggagccgga ggcgctggcg
     9841 tttatctccg gtcactatga aaccggcgag ccgctgccga aagagttgct ggataaaatg
     9901 ttggcagcga aaaattacca ggcggcgctg tttattctgc gccagctgga gttcggcctg
     9961 ttcgatttcc gcctccatgc cgagttccgt ccggatcagg gggcgaaaat cctcgaaact
    10021 ctggcagaaa tcaagaaact ggttgccgtg gtaccgtctc cgtcatgggg ccgtttcccg
    10081 catgctttca gccacatttt tgccggtggt tatgcggcag gttactacag ctacctgtgg
    10141 gccgatgtac tggcggcaga tgccttctcg cgttttgagg aagagggcat tttcaaccgt
    10201 gaaactgggc agtcgttcct cgacaacatt ctgagccgtg gcggttcaga agagccgatg
    10261 gagctgttca aacgcttccg tggtcgtgaa ccacagctgg atgcgatgct ggagcattac
    10321 ggcattaagg gctgatcatt cagtgaaaat ctgcttaatt gatgaaacag gcgccggaga
    10381 cggcgcctta tctgttctgg cggcccgctg ggggctggaa cacgatgaag acaacctgat
    10441 ggcgctggtg ttaacgccgg agcatctgga actgcgcaag cgtgatgagc cgaaacttgg
    10501 cggcatcttt gttgattttg ttggcggagc gatggcgcac cgacgcaaat tcggcggtgg
    10561 tcgcggagag gcggtggcga aagcggtggg cattaaaggc gattatttgc cggatgtggt
    10621 ggacgccacc gcagggctgg ggcgcgatgc ctttgtgctg gcttcggtcg gctgccgcgt
    10681 gcggatgctg gagcgtaatc cagtggttgc cgcgttgctc gacgatggtc tggcgcgtgg
    10741 ttatgcggat gcggaaatcg gcggctggtt acaggaacgt ttgcagttga ttcacgcctc
    10801 cagtctgacg gcgctgagcg atatcacccc gcgtccgcag gtagtttatc ttgacccaat
    10861 gttcccgcat aagcagaaaa gcgcgctggt gaaaaaagag atgcgcgtgt ttcagtcgct
    10921 ggtggggccg gatcttgatg ccgatggatt gctggagcct gcgcagttgc tggcaaccaa
    10981 acgcgtggtg gtaaagcgtc cggactatgc gccgccgctg gcgaatgtcg ccacgccaaa
    11041 cgcggtagtc actaaagggc atcgctttga tatttatgcc ggaacgccgg tgtaaaagta
    11101 aagcggggta gcgataacgc taccccgctt tctgcaagaa taattaatgg ctttccggcg
    11161 tcgcaatcat gcgtttcagc cacggcacca tcaatagcat cactactgca acgcccagcg
    11221 taaccaggcc aatcttacca aacacgttgg tatagacggg caacgtctca agtggatcgg
    11281 taatgttgtc tggtactgcg gtaaatgttg ccacatagcc gcccagcaag aacgcggcag
    11341 cctgcgtcag gaaccacatc ccgagaataa agcccatcaa atgctgcggc accagggcag
    11401 caatcatcgc caggccaagg gcgctaataa acagttcacc taagctctgg aataagtaca
    11461 ccagcacgat aaaccatggc gatgtcagcc cttgggcatc cgcaaaccac attccagccg
    11521 ctgcagccgt caaaaagccc agtgagcaca taaacatgcc gagagtaaac ttcatcggca
    11581 tcgagagatc tttgcctttg ttacccagtt gcgtgtaaat gcctgccagt attgggctgg
    11641 cgagtaccac ccagaacggg ttaagcgcct ggaagctgac cgggttgatg gaaaagccga
    11701 gaatttcatg atgcacgttg ttgatggcaa agaagttcag cgacgttggc atctgggcgt
    11761 agagaatgta aaacaccacc gcttcgagca tcaggacaaa ggcgacaaac attttattgc
    11821 gcccggtttt atccagcttg aatgcctgac gaaagaagat gatggtgacg acgatggaga
    11881 gaacaatcag caccagattg gcgacttcta cgttgtgcat cagccaggcg cagacgaaga
    11941 tcatcaccac gctgccaagt aatacgtaca acagtttact gaagctcatc ggccggaagt
    12001 cgggttcaga accaatatct ttcaccattc cacgacaggc gatgtaaacc agtaatgcga
    12061 taattaaccc tgcaccgcac aggttgtagg tgactgaata gccgaattta tcagcgatca
    12121 caggggccag cgataacgct atcaacgagc cgatattgat cgacatatag aacagggtga
    12181 atgcgccatc aagccgtgga tctttcggcg gatagcattt cgaaagcaag ctggctgggt
    12241 tagctttaaa caggccgtta ccgacagcga tagtccccag ggcgatgaaa atcaggtcag
    12301 gcttaagtag cgacatgccg gtcatgaagt agccaatcgc cagcacaagt gctccgagaa
    12361 caatggtgcg tttggttccc agcaggtggt cgccaacata gccaccaatg gaaatgaggc
    12421 catagaccag cgcagcaaaa gcaccaaaag tgacaaaagc ctgctcttgc gagaacccaa
    12481 gctgtttaac gaagaaaacc gccagtacgc cctgcacgcc gtagtagccg aatcgctccc
    12541 ataactcgac aaaaaagatc atgaaaaatg ggcgaggttg ctgcagcatc cccatgggtg
    12601 ttgttgtatt catatttatt aaccttccaa taccatcctg aaaagtatga acgcgtaagg
    12661 gataacgcgc gaaaaagttt acatctgtca gagattctta atattgatgc ggcgaataga
    12721 ttaatacact attacaacag aaaataacca gctgatcaca ctaatgatag aaaatatgat
    12781 ggtgttaaat gttgtattgg caggggtttt aattgcgtac gcagaccgca ggccagataa
    12841 ggcgtttacg ctgcatcagg taacaaggcg cgccaaaaag caaaacgccc gcatatgcgg
    12901 gcgttcagga acacgtcgtg gagggaagat tattcttctt cgtcgcgcag cggaacaatc
    12961 agcatatcaa cgtgaacggt gttgatcagc tgacgtgcgg aagacatcag tttgctccag
    13021 aagtcctggt ggtgaccaca aaccaccaga tccatatcgt atttcttgat tgcatcgacc
    13081 agtacctggc ccagatcgcc gctgccgctc agggtttcag tgattgggta gcctgcattg
    13141 gttgaaagct cggtcagcgc atgatgtgtc tcttcagaga tgcgtttctg catatcaccc
    13201 agattcacat cgataagccc ggtgtatagg tcagagtagt ttacatctac gtggatcaga
    13261 gaaactttcg cattgtaggg gcgagccata gagactgctt tctctaccag aactttgctt
    13321 tccggggaga ggtcgaccgc gatgagaatg tgtttataag ccatagtgtt actccttcca
    13381 taaagttgtc gatgactggc cagctagcgt ttcttgtgcc gttacgtcac ccgcgtcctg
    13441 cgaactacgt gcgcggggct aacccagccg taaagattca gtgttaagac catccttacc
    13501 ttatagcgac ccggatgatc cgtcaatccg ccttgcttac tcgttagata aacaaatttt
    13561 cgacatgaat atattgatag tggttaacct tctggaaaaa aaacaacctg atctcctaca
    13621 ctatctatag agccgctcgg atgttggtca ccacaaaagc ggtttctcca ggacctggtg
    13681 ttaactgatt ggcagcgtat cgggagcggt agccccgggg tggaactccg cgggcaggtc
    13741 gccggggagg aggtatgata agcaccgtcg cattattttg ggctttatgt gtcgtttgca
    13801 ttgttaacat ggcgcgctat ttctcatcac tacgcgcgtt gttagtggta ctgcgtaact
    13861 gcgatccatt gctctatcaa tatgttgatg gagggggctt ttttacctca catggccaac
    13921 caaacaaaca ggtgcgtctc gtttggtata tctatgccca acgttatcgc gatcatcacg
    13981 atgatgagtt tattcgccgc tgtgagcggg tgcgtcggca gtttattctg accagcgcat
    14041 tgtgtggtct ggtggtggtc agcctgattg cattgatgat ttggcattaa gcacttcagc
    14101 aataatgacg cataaaaaaa gcgggccagt aaactgaccc gctcgttttg gtgcgtacaa
    14161 ttacaggaac tgcaaggaga gccagtacag cccgccggaa agcagtaccg cagccggaag
    14221 ggtaaacacc caggccatca gaatactggt tacggtttta cgctgtaagc cgccgccatc
    14281 taccaccatc gtccccgcga cagaagagga gagtacgtga gtagtggaaa ccggcatccc
    14341 ggtataactt gccaggccga tagacacagc cgccgtcatc tgggcagaca tcccctgagc
    14401 gtaggtcatg cctttcttac cgattttctc accgatagtc gttgccacac gacgccagcc
    14461 aatcatcgta ccgataccta acgccagcgc gaccgccatg atgatccaca ccggcgcata
    14521 ctcgatggtg ctaagcatgt cggacttcag tttcttcaac aggcgctgat cgtcagcact
    14581 cacgccaggc attttcacca ctttatcgat agtgtcagaa acgcacagca taatgcggcg
    14641 catctggcta cgttgatcaa gcgacagctt gtcgtagctt tccacatcgg tagtcaacat
    14701 gcctttcagg cggttgagcg cgttaatggt attcgacgga tggcaatgga actccgcggg
    14761 ttgcgttgcg ccagcttccg gagccggtac taactgatca gcaccggtcg cttgtttcag
    14821 cagtgcagga tgctgctcaa agtaagcttc gacgttgttg atggcatcac gggtacgggt
    14881 gatttcgtag ccagtggcat tcatgttcac cacgaagcct gctggtgcga cgccaatcaa
    14941 taccaacata accagaccaa tgcctttctg accatcgttc gcgccgtgcg aaaacgccac
    15001 gccgatagcg gaaaggatca gcgcaatacg cgtccagaac ggcggctttt tcttgccgtc
    15061 tttcttttca cgctccgctg gggtcaggtg gatacgggcg cgtttcttgg tgccgctcca
    15121 gtagcgacgc agcaagaaaa tcagaccgcc agcaaacacc aggccgacaa taggggaaac
    15181 gatcagagaa ccgaaaatac ttaatacttt cgggatattg agtgcatcca ccactgacgt
    15241 cccggtcatc aacgcattgg ttaaaccaat cccgatgatc gcgccaatca gcgtatgaga
    15301 gctggatgca ggtaaaccaa agtaccaggt acccaggttc cagataatcg ccgccagcaa
    15361 catagagaac accatggcaa ggccatgaga cgatcccata ttaagcagca gatccgtcgg
    15421 cagcatatgc acaatggcat aggcaacact cagaccaccc agcaaaacac ccaaaaagtt
    15481 gaataccgcc gccataacca cggcgagctg agaacgcatc gcgcgggtat agataacggt
    15541 tgccacggcg ttggctgtgt catggaaacc attgatggct tcgtagaaca gcacaaaagc
    15601 cagtgcaagc aataataaca gcccggtatg caaatccagg ccagcaaaca aatgtagcat
    15661 aggacgttac gccattttga ggacatgaac gcggcgcatt atcagtgact ttcgcggcgc
    15721 gggcaaagtg aaatatagac tttttttgat ttgcctcctg tatggattcc actcaaaaaa
    15781 taattatc
//
LOCUS       DAPOXO010000104        15324 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPOXO010000104 DAPOXO010000000
VERSION     DAPOXO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15324
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.104"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1282)
                     /locus_tag="ROH59_004248"
     CDS             complement(<1..1282)
                     /locus_tag="ROH59_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDX4806656.1"
                     /translation="MANENLDIDSKTAEELYEWYLDDKLIINRRYQRKLVWSLEEKTA
                     LISSMTQQYPIPLLLFVSIDNKREILDGMQRLEALMSFIEQRFSLNGKYFNLDAIALT
                     KQLKDSGKLQQKEPVLSRESSTLIARYRFAISEYSSTEDHIDEVFRRINSNGKILSKQ
                     ELRSAGCVSNFSELVRKISTIIRGDTTHSDIMGLNKIHNISICNDGLDYGINIDNHFY
                     IRNHIISRPSIRDSDDEELVANILGYIFLDDKPTSGSTSLDTFYGEGSTSHAIHTRTQ
                     LENYIQTNGADKIVNNYLFVYEMIQKLFDANNLNFRSHILGNASSSQECPRYYQAVFL
                     ALYELIINENMQLDDEQKFIAQLGDSVQRSMVQTEGGRWAASARQKSVEDLCALIRRY
                     FKESENKFINHAWQTLIRTLLNNSRTEQPNYDFKQ"
     gene            complement(1567..1968)
                     /gene="pemK"
                     /locus_tag="ROH59_004249"
     CDS             complement(1567..1968)
                     /gene="pemK"
                     /locus_tag="ROH59_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001398199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin
                     endoribonuclease PemK"
                     /protein_id="HDX4806657.1"
                     /translation="MLKYQLKNENGWMHRRLVRRKSDMERGEIWLVSLDPTAGHEQQG
                     TRPVLIVTPAAFNRVTRLPVVVPVTSGGNFARTAGFAVSLDGVGIRTTGVVRCDQPRT
                     IDMKARGGKRLERVPETIMNEVLGRLSTILT"
     gene            complement(1901..2158)
                     /gene="pemI"
                     /locus_tag="ROH59_004250"
     CDS             complement(1901..2158)
                     /gene="pemI"
                     /locus_tag="ROH59_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PemI"
                     /protein_id="HDX4806658.1"
                     /translation="MHTTRLKRVGGSVMLTVPPALLNALSLGTDNEVGMVIDNGRLIV
                     EPYRRPQYSLAELLAQCDPNAEISAEEREWLDAPATGQEEI"
     gene            complement(2251..2904)
                     /locus_tag="ROH59_004251"
     CDS             complement(2251..2904)
                     /locus_tag="ROH59_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001757010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDX4806659.1"
                     /translation="MIQTRNQYLQFMLVMLAAWGISWGARFVMEQAVLLYGSGKNYLF
                     FSHGTVLMYLLCVFLVYRRWIAPLPVVGQLRNVGVPWLVGAMAVVYVGVFLLGKALAL
                     PAEPFMTKLFADKSIPDVILTLLTIFILAPLNEETLFRGIMLNVFRSRYCWTMWLGAL
                     ITSLLFVAAHSQYQNLLTLAELFLVGLITSVARIRSGGLLLPVLLHMEATTLGLLFG"
     gene            complement(3002..3142)
                     /locus_tag="ROH59_004252"
     CDS             complement(3002..3142)
                     /locus_tag="ROH59_004252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004031751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806660.1"
                     /translation="MAESGYGLAGLGMGKVKSINQYRLTPGFGGFTPVSYETTECRLP
                     CR"
     gene            complement(3842..4699)
                     /gene="repA"
                     /locus_tag="ROH59_004253"
     CDS             complement(3842..4699)
                     /gene="repA"
                     /locus_tag="ROH59_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HDX4806661.1"
                     /translation="MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSR
                     FDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPSDITFTPALFAALDV
                     SEDAVAAARRSRVEWENKQRKKQGLDTLGMDELIAKAWRFVRERFCSYQTELKSRGIK
                     RARARRDANRERQDIVTLVKRQLTREISEGRFSASREAVKREVERRVKERMILSRNRN
                     YSRLATASP"
     gene            complement(4692..4766)
                     /gene="tap"
                     /locus_tag="ROH59_004254"
     CDS             complement(4692..4766)
                     /gene="tap"
                     /locus_tag="ROH59_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HDX4806662.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
     gene            complement(4999..5259)
                     /gene="repA"
                     /locus_tag="ROH59_004255"
     CDS             complement(4999..5259)
                     /gene="repA"
                     /locus_tag="ROH59_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HDX4806663.1"
                     /translation="MSQIENAVTSSPKRIYRKGNPLTGAEKQRISVSRKKGTHKAINV
                     FIQSELKDDLTQLCKDSGLTQKEMIEHWILKEKAAMTDANRK"
     gene            complement(5499..6089)
                     /locus_tag="ROH59_004256"
     CDS             complement(5499..6089)
                     /locus_tag="ROH59_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="HDX4806664.1"
                     /translation="MKLIIFILIVLIIAALLIRIILRSVNQHSPLLMQLHAAGIRTGD
                     AERILSGGEYWQRQKTLLTEREVSFMKGLFRIVDMKRWYLCPQVRVADIVQLNGNIRP
                     RSRQWWQLFRMVSQWHVDVVIVERRSFSIVAAVELDDASHLRPERRRRDILLEEVLRQ
                     AGIPLLRSHDARKLLQMTGEWLNTTGAVQQSPEYRS"
     gene            complement(6127..6336)
                     /gene="hha"
                     /locus_tag="ROH59_004257"
     CDS             complement(6127..6336)
                     /gene="hha"
                     /locus_tag="ROH59_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDX4806665.1"
                     /translation="MAKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAA
                     DHRLAELITGKLYDRIPKEIWKYVR"
     gene            complement(6382..6843)
                     /locus_tag="ROH59_004258"
     CDS             complement(6382..6843)
                     /locus_tag="ROH59_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDX4806666.1"
                     /translation="MRKYIPLVLFIFSWPVLCADIHGRVVRVLDGDTIEVMDSRKAVR
                     IRLINIDAPEKKQDYGRWSTDMMKSLVAGKTVTVTYFQRDRYGRILGQVYAPDGMNVN
                     QFMVRAGAAWVYEQYNTDPVLPVLQNEARQQKRGLWSDADPVPPWIWRHRK"
     gene            complement(7088..7300)
                     /locus_tag="ROH59_004259"
     CDS             complement(7088..7300)
                     /locus_tag="ROH59_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001369432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANR family transcriptional regulator"
                     /protein_id="HDX4806667.1"
                     /translation="MNGTGRDSQNSGVWRYRQVGRRAVRLEVRGDWPGAAEAWLRAAQ
                     SAPRTDWQQFARKRAEHCHRRCRGRV"
     gene            complement(7429..7989)
                     /locus_tag="ROH59_004260"
     CDS             complement(7429..7989)
                     /locus_tag="ROH59_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HDX4806668.1"
                     /translation="MTEQKRPVLTLKRKTEGETPTRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELTAKKAQARQALSIYLNLPSLDEAVNTLKPWWPGLFDGDTPRLLACGIRD
                     VLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEV
                     YAAERLDKIRRQNRIKAELQAVLDEQ"
     gene            complement(8092..8952)
                     /locus_tag="ROH59_004261"
     CDS             complement(8092..8952)
                     /locus_tag="ROH59_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4806669.1"
                     /translation="MKITDHKLSEGIALTFRVPEGNIKHPLIILCHGFCGIRNVLLPC
                     FANAFTEAGFATITFDYRGFGESDGERGRLVPAMQTEDIISVINWAEKQECIDNQRIG
                     LWGTSLGGGHVFSAAAQDQRVKCIVSQLAFADGDVLVTGEMNESERASFLSTLNKMAE
                     KKKNTGKEMFVGVTRVLSDNESKVFFEKVKGQYPEMDIKIPFLTVMETLQYKPAESAA
                     KVQCPVLIVIAGQDSVNPPEQGKALYDAVASGTKELYEEADACHYDIYEGAFFERVAA
                     VQTQWFKKHL"
     gene            complement(9011..9757)
                     /gene="traX"
                     /locus_tag="ROH59_004262"
     CDS             complement(9011..9757)
                     /gene="traX"
                     /locus_tag="ROH59_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="HDX4806670.1"
                     /translation="MTTDNTNTTRNDSLAARTDTWLQSFLVWSPGQRDIIKTVALVLM
                     VLDHINLIFQLKQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQF
                     AYYLAGFPWYEGNILFAFAVAAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAG
                     LLMLAVSYRLYRAEDRAERLALLACLLAVIPALNLASSDAAAVAGLVMTVLTVGLVSC
                     AGKSLPRFWPGDFFPVFYACHLAVLGVLAL"
     gene            complement(9777..15047)
                     /gene="traI"
                     /locus_tag="ROH59_004263"
     CDS             complement(9777..15047)
                     /gene="traI"
                     /locus_tag="ROH59_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HDX4806671.1"
                     /translation="MLSFSVVKSAGSAGNYYTDKDNYYVLGSMGERWAGQGAEQLGLQ
                     GSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSMMAMLGGDKRL
                     IDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHV
                     VVANVTQHNGEWKTLSSDKVGKTGFSENVLANRIAFGKIYQSELRQRVEALGYETEVV
                     GKHGMWEMPGVPVEAFSSRSQAIREAVGEDASLKSRDVAALDTRKSKQHVDPEIRMAE
                     WMQTLKETGFDIRAYRDAADQRAEIRTQAPGPASQDGPDVQQAVTQAIAGLSERKVQF
                     TYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSV
                     RALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVA
                     ELVMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQEGMVFTPGSTVIVD
                     QGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQR
                     PATIISEPDRNVRYDRLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVL
                     GHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLT
                     LRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASV
                     SEDAMTVVVPGRAEPATLPVADSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMD
                     NATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAISLQ
                     KTGLHTPAQQAIHLALPVLESKNLAFSMVDLLTEAKSFAAEGTGFTELGGEINAQIKR
                     GDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMETLTSG
                     QRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPASERPRVVGLGPTHRAV
                     GEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIA
                     AGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELREAVYSLINR
                     DVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGETFPDV
                     PMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMEP
                     VLNTANIRDGELRRLSTWENNPDALALVDSVYHRIAGISKDDGLITLEDAEGNTRLIS
                     PREAVAEGVTLYTPDKIRVGTGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQ
                     QTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVAL
                     SRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAQRLFSTARELRDV
                     AAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGN
                     GLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGE
                     GRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEI
                     VRKMAENKPDLPDGKTELAVRDIAGQERDRSAISERETALPESVLRESQREREAVREV
                     ARENLLQERLQQMERDMVRDLQKEKTLGGD"
     gene            complement(15047..>15324)
                     /locus_tag="ROH59_004264"
     CDS             complement(15047..>15324)
                     /locus_tag="ROH59_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000009331.1"
                     /note="type IV secretion system coupling protein; similar
                     to F plasmid TraD; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein TraD"
                     /protein_id="HDX4806672.1"
                     /translation="SSVINDKKSDAGVSVPAGGIEQELKMKPEEEMEQQLPPGISESG
                     EVVDMAAYEAWQQENHPDIQQHMQRREEVNINVHRERGEDVEPGDDF"
BASE COUNT         3473 a         4403 c         3539 g         3909 t
ORIGIN      
        1 cctgtttaaa atcataattt ggttgttctg ttcttgagtt attaagtaga gttcttatca
       61 gtgtttgcca agcatgattg ataaatttat tttctgattc tttaaaatat cgtctgatta
      121 aagcacataa atcttcgaca cttttctgac gagcgctagc tgcccaacgg cccccttcgg
      181 tttgcaccat tgaacgttgt acactgtctc ctaactgagc gataaatttc tgttcatcgt
      241 caagttgcat gttttcattt atgattaatt catacaaagc aagaaaaaca gcttgatagt
      301 aacgaggaca ttcttgagat gaagatgcat tgcccagaat gtgtgatcta aagttcaaat
      361 tatttgcatc aaataatttt tgaatcatct cataaacgaa gaggtaatta ttgacaattt
      421 tatctgcacc atttgtctga atgtaattct ctaattgagt tcgtgtatgg attgcatgac
      481 tcgtcgaacc ttcaccgtaa aatgtatcga gcgatgttga tcctgatgtt ggcttatcat
      541 ctaaaaatat atagcccaag atatttgcaa ctaactcttc atcgtcagag tctctaatgc
      601 taggcctact aatgatatga tttctaatat agaaatgatt gtctatattt attccataat
      661 cgagtccatc attgcaaatt gatatgttat gtattttatt cagtcccatt atatcgctat
      721 gtgtagtatc tcctcttata attgtcgata ttttccttac taactctgaa aaattactaa
      781 cgcaccccgc acttcgtagt tcttgttttg ataaaatttt accattggaa tttatgcgtc
      841 gaaacacttc gtcaatgtgg tcctctgttg aagagtattc agatatagca aatctatagc
      901 gagcaattaa tgtagaactt tcgcgggata gcactggctc tttttgttga agtttaccac
      961 tgtcttttag ttgttttgtt aatgcaatgg catctaaatt aaagtattta ccatttaatg
     1021 aaaatcgctg ctcaataaaa ctcattaaag cttctagtct ttgcattcca tcaaggattt
     1081 ctcttttgtt gtcaatggaa acaaacaata gcaaagggat agggtattgc tgagtcattg
     1141 atgaaatcag tgctgttttc tcttcgaggg accatactaa ttttctttgg tatcttcgat
     1201 ttataattaa tttatcatcc agataccact cgtataattc ttctgctgtc ttggagtcaa
     1261 tatctaagtt ttcattagcc attagatgta tctcgagtat ttagttaaga aactgatagg
     1321 tcagtatttg catcaatgtt cattgaattt gtatccgaag tcaatctgat gtaggaactt
     1381 caaaactgcg caaaacacgc aaatacgcac aagaaagtag ggctgcgctt ggaattcgga
     1441 aaataaacca catcaaaact actttttagc caaataacgt ttgggaatca ccagaatggt
     1501 gggacaacag cggttttagt gccctaaatc gtacgttttc atccagttgc ccctcaaacc
     1561 ccatgttcaa gtcagaatag tggacaggcg gccaagaact tcgttcatga tagtctccgg
     1621 aacccgttcg agtcgttttc cgccccgtgc tttcatatca attgtccggg gttgatcgca
     1681 acgtacaaca cctgtggtac gtatgccaac accatccaac gacaccgcaa agccggcagt
     1741 gcgggcaaaa ttgcctccgc tggttacggg cacaacaaca ggcaggcggg tcacgcgatt
     1801 aaaggccgcc ggtgtgacaa tcagcaccgg ccgcgttccc tgctgctcat gacctgcggt
     1861 aggatcaagc gagacaagcc agatttcccc tctttccatg tcagatttcc tcctgaccag
     1921 tcgccggtgc atccagccat tctcgttctt cagctgatat ttcagcattc ggatcacact
     1981 gtgccagtag ctcagccagt gaatattgcg ggcgtctgta cggctcaaca atcagccggc
     2041 cattatcaat gaccatgcca acttcattat ctgtgcccag agacagcgca ttcagcagtg
     2101 ccggtgggac ggtcagcata actgagccgc caaccctctt cagtcgggtg gtatgcattc
     2161 ttcacctcca taaaagttat atttaaatat aacatccact aaaaaaacac accaggcttt
     2221 aacgcacaat gtttaataaa aatataactt tcaaccaaac agtaaaccca gcgtggttgc
     2281 ttccatatgc agcaataccg gcagcagcag gccaccactt ctgatcctgg ccactgatgt
     2341 aatcaacccc accaggaaca gttctgccag tgtcagcagg ttctgatact ggctgtgcgc
     2401 ggcgacgaac aacaacgacg ttatcagcgc ccccagccac atcgtccagc agtaccgtga
     2461 acggaagacg ttcagcataa tcccccggaa cagcgtttcc tcattcaacg gggcaaggat
     2521 aaagatggtc agcaacgtca ggatcacgtc aggtatggac ttatcggcaa aaagtttcgt
     2581 cataaatggc tcagcaggca gagccagcgc cttaccgagc agaaatacac cgacatacac
     2641 cacggccatc gcaccgacca gccacggtac gccaacgttg cgcagctgac caacgaccgg
     2701 tagcggagct atccaacggc ggtataccag gaaaacacac agcaggtaca tcagaacagt
     2761 accatgactg aagaacaaat agttttttcc tgatccataa agcagaacgg cctgctccat
     2821 gacaaatctg gctccccaac taatgcccca tgcagccagc ataaccagca taaactgcag
     2881 atattgatta cgtgtttgaa tcattgcatc gcctgtaaat ttttaacttg tcctattttt
     2941 gtcattacca cgtatataca catgtataac aattcagata tcgttaccag gatatgccgc
     3001 atcagcggca tggaaggcgg cactctgttg tttcatatga tacaggagta aaaccgccga
     3061 agcccggcgt aagccggtac tgattgatag atttcacctt acccatcccc agccctgcca
     3121 gaccataccc gctttcagcc atgagagagc ttctgtgcgc ggtcggagtg gtcccgacga
     3181 gggtttaccc gaagtcgggg cgtatctccg cgttagcggg ccgtgagggc cgcttacgag
     3241 cgtgtactga gaacttccag cgagaagact gacagcgatg aagatgtagt tacaacattc
     3301 ataattaaaa gcgactctgt tccggcccga agggccgggg cggggccgct tttcagttat
     3361 gaggaggggc tttgtggttt cagttctgcg ctggactggg gttttcccgg tgcttgtatt
     3421 tgagtgttgt aactaaaatg gctccggttg gggcccgccg cttgcggtgg gaggtgcata
     3481 tctgtctgtc cacaggacag gcagtgaaca ggttttcttt ttaaatgaat gtaattaagt
     3541 agtttaaagg agatataaac aggtgtttaa aagatacatt gcaccctgta acgctggcgg
     3601 atggcgcttt atgacatgaa cggttgtaac cttatgggga agtcccttgc agtttaatgt
     3661 ggataagcaa aattccccgt ctgtgaggcg tgttttgtat caaaaacaga gagaaccgga
     3721 tgcatctgaa agtggatgat gaggttgttt tttgtatgtg gtgctgtttt tttctgtact
     3781 ggcgggcttc agacgtgcgg attcctccgg cgcaggccgg attattctga ggaggtcact
     3841 ttcaggggga agcggtggcc agccggctgt aattgcggtt acgtgacaga atcatgcgct
     3901 ccttcacacg acgctccact tcacgtttta ccgcctcacg actggcagag aagcgccctt
     3961 ccgagatttc acgcgtcagc tgccgtttca ccagggtgac gatatcctga cgttccctgt
     4021 tcgcatcacg acgcgcacgg gcacgtttta ttccacggga cttaagctct gtctggtaac
     4081 tgcagaaacg ctcacgcaca aaacgccagg ctttcgctat cagctcatcc atacccaggg
     4141 tatccagccc ctgctttttg cgctgtttgt tttcccattc aacacgactg cggcgcgcag
     4201 ctgccactgc atcctcagac acatcaaggg cagcaaacag agccggtgtg aacgtgatgt
     4261 cgctcggaat gtagcacccg ataagcgggt catattccgt ctggtaggta atcagtccca
     4321 gctctgacag gaacgtcagg gcccgggtgg cacgggtgat ggagagtttt cctgcaccgg
     4381 actctgtcgc cagtccgcac tcaatggcca gcgtggtgat ggagcactgg acgcggttgg
     4441 ccagcggatc atagtgaaaa cagagtccct gcagcagcgc atcaatagcc cgtcgacgca
     4501 gcaccggtgg catgcgccga cgcaaaccac gggaacgggc atgcgccaca tgaatggcga
     4561 aatcaaaacg ggaggtgaag cccaccgcct tttccatcag tttttcgcag aacttcaacg
     4621 ttccggcacc tttacggggt gtaaacaccg gattcgggtt ctttacctgg cggtaatacg
     4681 tttgttgaag atcagtcaca ccatcctgca cttacaatgc gcagaaggag cgagcacaga
     4741 aagaagtctt gaacttttcc gggcatatga ctatactccc cgcatagctg aattgttggc
     4801 tatacggttt cttgttagcc ccggtaatct tcttcgtcgc caaacataga aagattatcg
     4861 gggtttttgc ttttttggct cctgtaaatc cacatcagaa ccagttccct gccaccttac
     4921 ggcgtggcca gccacaaaat tccttaaacg atcagtaatc tagcatccgc aattcaaatg
     4981 ttcaagaagg taacttagtt actttctatt cgcatcagtc atcgcagctt tttctttcaa
     5041 aatccagtgc tctatcattt ctttttgagt taagcccgaa tccttacaaa gctgtgtcaa
     5101 atcatctttg agttcactct ggatgaaaac attaatcgct ttatgtgtcc cctttttccg
     5161 ggaaacagat atgcgttgtt tctcggctcc ggttaacgga ttaccttttc tgtaaatgcg
     5221 tttcggtgag gaagttactg cattttcgat ctgcgaaatc tcgcctcctc aatactcaaa
     5281 cagggatcgt ttcgcagagg atactacagt tttttgaaat cagcgacttg agaattgtga
     5341 cgaagatctg tgttggcgca caaatcaacg gggattactg tcgtttaatg tgatttaaac
     5401 tgtgaaatag tatggttttc agttatggaa acgccgggag cggggaaaac ttgctttttc
     5461 ccgtttccgg ggttggacaa ctgagcaacg cgaaggcgtc agctacgata ttccggtgac
     5521 tgctgaacag cccctgttgt attcagccat tctccggtca tctgcagcag ttttctggca
     5581 tcgtggcttc tgagcaacgg aataccagcc tgcctcagaa cctcttccag aagaatatcc
     5641 cggcgtctgc gttccggtcg taaatggctg gcatcatcca gctctactgc tgcaacaata
     5701 ctgaacgaac gccgctcaac gataaccaca tcaacatgcc actgagacac catcctgaat
     5761 aactgccacc actggcgtga tcgtggccgg atattcccgt tcagctggac gatatccgcg
     5821 acccgtacct gcggacacag ataccaccgc ttcatatcca caattctgaa cagtcctttc
     5881 ataaaactga cttccctttc tgtcagcagc gtcttctgac gttgccagta ttcaccgccg
     5941 gacagtattc gctctgcatc accggtccgt atacctgccg catgcaattg catcagcaaa
     6001 ggagaatgct gatttacact tctgaggata atccggataa gtaacgctgc aataatcaga
     6061 acaataagaa taaaaataat cagcttcatt gtttatctgc tcctggtaat taattatgct
     6121 gaattattac cttacatatt tccatatctc ttttggtatc ctgtcatata actttccggt
     6181 gattaattcc gctaaccggt ggtctgctgc tgaattaaat gattcacgtt cactgtttaa
     6241 taaactgtct ctgtttttat gaataatttt ttccagcgta ttgactgatg aacatcgccg
     6301 taactgatac agccattcct gttttgtttt cgccattttt attcccgctg agaacagatg
     6361 aatgataaga ttgccatcgc tttatttacg gtgtctccat atccaggggg gaaccggatc
     6421 agcatctgac cagagcccac gtttttgttg tctggcttcg ttctgaagga caggcagcac
     6481 gggatctgtg ttgtactgct catataccca ggcagccccg gcccggacca taaactgatt
     6541 aacattcatt ccgtctggtg cataaacctg cccgagaata cgaccataac gatctcgctg
     6601 aaaatatgtg acggtaaccg tttttcctgc aaccagtgat ttcatcatgt ccgttgacca
     6661 ccggccataa tcctgtttct tttccggtgc atcaatattt atcagcctga tccgcactgc
     6721 cttccgtgag tccatgacct cgatggtatc accgtccagt acacgaacaa cccgtccatg
     6781 aatatctgca cacaataccg gccatgaaaa gataaataat accagtggaa tatatttcct
     6841 catgttattc tccatatcag ataaatggca cctgtatttc aggtaatcct gaatatcgca
     6901 gcacacactg aataacacct tattttgtga aattaatcac aaaatataaa atcacgactt
     6961 aatatggaaa aaactctgtg ctactcagaa ctgtccggtc atactttccg accggatatt
     7021 aaaaaaagca aatctcatgc attattcagc cttctgaatc cctggagtaa tgaaggctgc
     7081 tttttcgtta cacccttccc cggcagcgcc ggtggcagtg ttcagccctt tttcgggcaa
     7141 actgctgcca gtctgtccgg ggagcagact gcgcagcccg tagccatgcc tcagcggctc
     7201 ccggccagtc ccccctgact tccagccgga cagcccggcg tccgacctgc cggtagcgcc
     7261 ataccccgga gttttgcgaa tcacgccctg ttccgttcat tttccttccc cctttaatcc
     7321 aggccggtga atgtgttata aatttttata accttcttct gccgggtatg gaagaaggtt
     7381 tcagagaagc cttatttttc cgcctccttt agtgtgaagg aggctttttt attgttcatc
     7441 aagcacggcc tgaagttctg cctttatccg gttctggcgg cggattttat ccagacgctc
     7501 tgccgcatac acttcttcct cctgagaaat atgctccgtc acataccctt ccgtgtcata
     7561 ccggcaggca ccggctttca tggcacacag atagctttct gaacgggtga tggccttcag
     7621 cgccctgcgc agttttttat gcgagagcgg gatattccgc tgcgccacgt cttccagtaa
     7681 cacgtcccgg ataccgcagg ccagaagtcg gggtgtgtca ccgtcaaata atcccggcca
     7741 ccagggtttc agggtgttca cggcctcatc cagcgagggc aggttcagat aaatggacag
     7801 cgcctgtctg gcctgcgctt tttttgctgt cagctctgct tcccgggcag ccttctccgc
     7861 cagtttctgc tttttcacct tccattttgg tggcgtggtg acattgatga tggttttccg
     7921 gctccgggtc ggtgtttccc cttccgtttt ccgtttcagt gtcagtaccg gtcgtttctg
     7981 ctctgtcatg attgccctga cctttgtgaa aatatgtcct ccaggtcgtt gaaactactc
     8041 actatgatat taagctgacc tcaacgacct ctgacatatt aataccgaca attaaagatg
     8101 ttttttaaac cattgcgtct gtactgccgc cacacgttca aaaaacgcgc cttcataaat
     8161 atcataatgg catgcgtcag cttcctcgta taattcctta gtaccagaag caacagcatc
     8221 atataaggct tttccctgtt ctggtggatt aacactatcc tggccggcaa taacaatcaa
     8281 aactgggcac tgtactttgg ctgcgctctc tgccggttta tattgcaacg tctccataac
     8341 cgtaaggaaa ggtattttta tatccatttc aggatactga ccttttacct tctcgaagaa
     8401 tacctttgat tcattatcac tcagtacccg ggtaaccccc acaaacatct ctttcccggt
     8461 gtttttcttc ttctctgcca ttttattcag cgtggacaga aaagacgctc tctccgattc
     8521 attcatctct ccggtaacca gaacatcacc gtcagcaaaa gccagctggc tgacaataca
     8581 ttttacgcgt tggtcctgcg cagctgcact gaagacatgc ccccctccca gcgatgttcc
     8641 ccataaccca atacgctgat tatcaataca ttcctgcttt tctgcccaat tgataactga
     8701 aataatatct tcggtctgca ttgcaggaac cagacgccct cgttctccat cactctcacc
     8761 gaatcctcga taatcaaaag taatcgttgc gaatcctgct tctgtgaagg cattcgcaaa
     8821 gcaagggagc agaacattcc tgataccgca aaacccatgg cataagataa tcaaaggatg
     8881 ttttatattt ccttcaggaa cacgaaatgt cagggcaata ccttcagaga gtttgtgatc
     8941 cgtaattttc ataaatatcc tgtgttatgt tgtttattaa taatcagaat cagcgtcagt
     9001 atcataccag tcacaacgcc agaacgccca gcacagccag atgacaggcg tagaataccg
     9061 ggaaaaaatc cccgggccag aaacggggta atgattttcc tgcacacgac accagaccaa
     9121 cggtcagcac cgtcattaca agaccggcca ccgccgctgc atcactggag gcaaggttaa
     9181 gtgccggaat aacggccagc aggcatgcaa gcagcgccag acgttccgct ctgtcttccg
     9241 cccggtacag tcggtaactg accgccagca tcagcagccc ggcaatgccg taactggtgc
     9301 cggacaaagg cccccacagg gccatcagaa gaatggccgc tgctgtacgc cacccactgc
     9361 gcgtttcaca ccacgtcagc acctgtgccg ccactgcaaa ggcaaacagg atattcccct
     9421 cataccaggg aaagccggcc agataatatg cgaactgggc aataattccc catccccaca
     9481 gccggttaat ggccggttgc cggatatgcg catgacggga cagattcagc ccccacacca
     9541 gggcaaacag cggaaaggct cctcgcccgg ccagaaacat ccattcctgc ttcagctgga
     9601 atatcagatt gatgtggtcc agtaccatca gcaccagcgc caccgttttg atgatatccc
     9661 gctgtccggg tgaccagacc agaaacgact gcaaccaggt atcggtccgt gcagccagtg
     9721 aatcgttacg tgtcgtgttc gtgttatccg ttgtcatcag tgtttgtctt cctgtatcag
     9781 tctccgccca gggttttctc tttctgcagg tcacgaacca tatcccgctc catctgctgc
     9841 agacgctcct gcagcagatt ttcccgggca acctcccgga ccgcttcccg ctcccgttgt
     9901 gattcacgca gcacactctc cggcagtgcg gtttcccgtt cagatatggc agaccggtca
     9961 cgctcctgtc cggcaatatc cctgacagcc agctctgttt tgccatccgg caggtcaggt
    10021 ttgttctctg ccattttcct gacaatttca tctgcgcggc gttccgtttc acggcggatg
    10081 gcctcttcag cctgccgctg tgccagtacc tctgccgtga ccggttcgcc atttccggcc
    10141 cccggctgga cgctgttatc cgggatatcc ccccacacgc ggccaccggt gatggcaccg
    10201 ggattccacg gacgaccttc accggcaatt ctcaccacca caccgctgtc aggattatca
    10261 cgggcaatcc ggacgccatc ctgcatatta tcagccagca ggctctctcc gttacggctg
    10321 ccctgcaggg ccacgaactg cgcatccccg ctgcctttca cccgtccttc accactgaat
    10381 ccccgcagcc cgtttccgtc atccgtggtc agtgggttca gccagatacc agctgacttg
    10441 ccgttacggt caaacgccgg cagtgccaca tacggctgcg gatatttacg tcccggtgca
    10501 ataaaccgtg cagggctgtc tcccccggcc agccctgcct gacggagaac ggcacggcct
    10561 gccgccacgt cccgcagttc ccgtgccgta ctgaacagcc gctgcgcatt catgacctcc
    10621 cggtccggtt tcggctccag cacatcgtgg gcagttcctt tctgtacggc attgttaatg
    10681 gcatccgtcc agccctgacg gttatcggtg tacacctgca catgctgctt catacgcgac
    10741 agggccacgt aggctgactc aaagccggcc atcagtttcc ggttaccttc cgtgccttca
    10801 agcgcgatgg caaaggtttc actcgccccc tgcgcaccgt gggcggtgat ggcataagcc
    10861 aggtcaatat gttgctctgc ccgctcctgg ccggggcgaa tcacccgggt ctgctgtccg
    10921 tctgacagcg tgacactgtc accggaaacc gctgtcaccg tccagacgct gttggccaca
    10981 taaccgcgct cccggtcact cttcgtgaag cgcatccggt cgccggtccc cacccggatt
    11041 ttgtccgggg tgtacagtgt gacaccttca gccaccgcct cccggggcga aatcagccgc
    11101 gtgttacctt ccgcatcctc cagggttatc agcccgtcat ccttgctgat accggcaatc
    11161 cggtgataca cactatccac cagggcaagg gcatccgggt tattctccca ggtggagaga
    11221 cgacgcagct ccccgtcacg tatattcgct gtgttcagga caggctccat gacctgctct
    11281 ttccccagct caccggcctt ttcccgtgca tcatgaatca tgctgttcag tacgcgccgg
    11341 tcctcattca ggtgcgtgac aatcagcgtc tgctcccgtg cttccggtgt cctgccggta
    11401 tagtcgcgga caatggcttc atacagtgtc atggggacat ccggaaaagt ctcacctttc
    11461 agcatcgcct tctgctgcgc ttctgccagt ttcgcttcct ggctgtgact gaactccgtc
    11521 acggagtgct ccggtgccca tgcgccctcc tgacggggaa cctgagacgg tttcacactc
    11581 tcaagcccgg acagtgccct ttccacatcc cggttaatca ggctgtatac cgcctcccgc
    11641 agttccggcg tctgacgcac aatctccttc atgatgacca catcggcagc actgcgcgtc
    11701 tgctggagac ggaaaggctg accgggcgcg atggcctgca gctggtccgt gtcaccactg
    11761 gccacggcac gaccgccacc ggccgcaatc agggcgtatg cccgtgccat gtcggtattg
    11821 cccaccattg agctctcatc gagcaggaac agcgtgttgc tgaaatccgg cgtttctccg
    11881 ctgcgctgct gcagctgcgt gtcatgcaga aaggacgcca gcgtctgtgc atccacgccg
    11941 gcgctgcgca tctcaccgac cgcacggtgc gtgggcccca gccccacaac tcggggacgc
    12001 tcactcgccg gcagcatgtt cacggctgac atcaccgccc ggaactgtgt ggtcttaccc
    12061 acaccggcat aaccctgtac caccgtgaaa cggtcggacg tttccagtat catacgggtg
    12121 gcggcacgct gtcccgacgt taacgtctcc atgagttcgc cgggtactct ctccatcagc
    12181 ggcgtgaccg cctccttacc ttcgagaata tggcgaagaa tacttttttc tgcctcatac
    12241 gacgcacggg aaaccagcag gcctgtgcca tagccttttg ccacatccac atacagtaag
    12301 tcaccgcgtt ttatctgcgc attgatttcc cctcccagtt cagtaaaacc ggttccttct
    12361 gcagcaaacg acttcgcctc tgtcagcagg tccaccatgc tgaaggccag gtttttactt
    12421 tccagcacag gaagggccag atgaatggcc tgctgtgccg gcgtgtgcag cccggttttc
    12481 tgcagactga tagcggtttc cagcgatgtc tcaccggccc gcgcctttat ctgctcagaa
    12541 accaccgtaa aggagggatg gcgggcaagt ttttccgcag tacgggtttc atccagtgag
    12601 gaatacagcc ggacatcacg accgctgcgg gccagaccgt tcagggtggc gttgtccatt
    12661 gccatctgtg tgacggaggc aaacaccgtc gcactgtcac tgacggaatg cccgggcgtt
    12721 tccacccagc cgttctccag cttcagtgcc gtgaacggtg aatcagccac aggcagggtg
    12781 gccggttcag cccgccccgg cacaacaacc gtcatcgcat cttcactgac ggatgccacc
    12841 tgcaggcggt caccgccgga gacgcggagt ccgggaattt tccctgtcac cctcagtcgc
    12901 tcgccgtctg ccaccggcat tttttccggc cggaacagcg accagctgct gtccagggag
    12961 gaaatacgca ccacctgcgt ttcgccctgc gcatcccgca gggtcaggct gtgactctgc
    13021 gccgtcaccc ggtcgataac atagcggtca tgactgcgtg tctccgggtt ccactgctcc
    13081 atcaccatcc ccggtcggta catatcccgc agataacggc tccggctgtc cagccagacc
    13141 ggtgacaggg cggtcatggt cacctccggg tgtccgagca cgccctgtgt tttcagctca
    13201 ctgcgaatgg cctgtgtcag tatggcctgt tcccgtaccc cgctgacctg tgccacgctc
    13261 tcttctccgg ctttcacgct ggccgcaaaa tctccggcca gccggtcata gcggacattc
    13321 cggtccggtt cactgatgat ggttgccggt cgctgttctc cgccctgcca gcgatacgtg
    13381 ttcaccccgg catccttcat ggccatcagc gcactgcctg taccggttcg ctgcccgctg
    13441 tcggttatca ggacctgtac gttatgacgt gcggcaccgt ccagcagggt taacgtctct
    13501 ttcagggaga gtttttcgcc ctggtcgacg ataacagtac tgcccggcgt gaagaccatg
    13561 ccctcctgca gctgacgacg tccggttatc agctcaccgg acagccgttc atcctgcttc
    13621 aggttcatct gcgagcgacg gtcagcagcg ataatctgca cctcccgccc ctgctcccgg
    13681 gccatcatga ccagttcagc cacccgctca cgctgcccgg ctgcaccgcc ctgcccggac
    13741 acaatggcca gcgacggacg gtcctgtgcc agaacactga ccgcatcgct gtaaccagcc
    13801 gtccggggga cacttttctc cggatgtacg gtcacccggt tctgtttcat gatgtcacga
    13861 ctgagtgccc ggacggacag ctcatcgagc acatgaattc ctgatgtgaa cagccccttc
    13921 tcacggtcga gggggataag ctgctcacgg ctgatggcct catcgatacc ggcgcgtgcc
    13981 cgttcaatca caccattttc cggcggcagt atgccgaccg tcctggccag cacgtccgta
    14041 tacgtgaact gcacttttcg ttcacttaat ccggcaatcg cctgtgtcac cgcctgctgc
    14101 acatccggcc cgtcctgtga agcaggcccg ggcgcctgcg tgcggatctc cgcacgctga
    14161 tccgccgcgt cacgatatgc ccggatgtcg aacccggttt ccttcagcgt ctgcatccat
    14221 tcagccattc tgatttccgg atcgacgtgc tgtttggatt ttcgcgtatc cagtgccgcc
    14281 acatcccggg atttcagcga ggcgtcttca ccgacggcct ccctgatagc ctgtgaacga
    14341 ctggaaaagg cctccaccgg tacgcccggc atctcccaca taccgtgctt accgaccact
    14401 tcggtttcat aacccagcgc ctcaacgcgc tgacgtaact cactctgata tattttcccg
    14461 aacgcaatcc ggttcgctag cacgttctcg gaaaatccgg ttttccccac tttgtcactg
    14521 ctcagtgtct tccactcgcc gttatgctgc gtgacattag ccaccactac atgcgtgtgt
    14581 aactgtgggt cctgatcgcg actggtgtca tggttaaaca gtgccatcac cagattaccg
    14641 gtcagcaccg tttctgactg tccgtccgtc atcacccgtg tggaagccag cgcctccacc
    14701 tgacggacag caaaatccac ggcctggtta tgtgcatcaa taagacgttt atcccccccg
    14761 agcatggcca tcatggagac acttttgggg gcggagaagg tcaggtcgta gccgggacga
    14821 tgcttattac tgccatcctg catgcggctt aaatccgccc cgtccggcag cctgccctcc
    14881 agaagacggg taaaaacatc cttatcgacg ctgccctgca gcccaagctg ttcagccccc
    14941 tgaccagccc agcgttctcc catgctgccc agcacatagt aattatcctt gtcggtgtaa
    15001 tagtttccgg cactgcctgc cgatttaaca acgctgaaac tcaacatcag aaatcatctc
    15061 ccggctcaac atcctccccg cgctcccggt gcacattaat gttcacctct tcacgacgct
    15121 gcatatgctg ctggatgtcc ggatgatttt cctgttgcca tgcctcataa gcggccatat
    15181 ccaccacttc accggattca ctgatcccgg gtggcagttg ctgttccatc tcttcttccg
    15241 gtttcatttt cagctcctgc tcgatccccc ctgccggaac actcacacct gcatctgact
    15301 tcttatcatt gatgacagaa gaca
//
LOCUS       DAPOXO010000105        15139 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.105, whole genome shotgun sequence.
ACCESSION   DAPOXO010000105 DAPOXO010000000
VERSION     DAPOXO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15139
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.105"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(210..845)
                     /gene="nth"
                     /locus_tag="ROH59_004265"
     CDS             complement(210..845)
                     /gene="nth"
                     /locus_tag="ROH59_004265"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDX4806673.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAYGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(845..1540)
                     /gene="rsxE"
                     /locus_tag="ROH59_004266"
     CDS             complement(845..1540)
                     /gene="rsxE"
                     /locus_tag="ROH59_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxE"
                     /protein_id="HDX4806674.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDEKMKKRRTEAA
                     AERALPNGETGNV"
     gene            complement(1544..2164)
                     /gene="rsxG"
                     /locus_tag="ROH59_004267"
     CDS             complement(1544..2164)
                     /gene="rsxG"
                     /locus_tag="ROH59_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HDX4806675.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDANWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE"
     gene            complement(2168..3226)
                     /gene="rsxD"
                     /locus_tag="ROH59_004268"
     CDS             complement(2168..3226)
                     /gene="rsxD"
                     /locus_tag="ROH59_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HDX4806676.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMMLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTTSGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEEIMQYPIYSGILAGA
                     GWQWVNLAWLTGGVWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPDTLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(3227..5647)
                     /gene="rsxC"
                     /locus_tag="ROH59_004269"
     CDS             complement(3227..5647)
                     /gene="rsxC"
                     /locus_tag="ROH59_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDX4806677.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWADYRSRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSHDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKTARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEQQVDPRKAAVE
                     AAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQQANAEPEEQVD
                     PRKAAVEAAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQQANA
                     EPEEQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQIDPRKAAVAAAIARVQAKKAA
                     QQKVVNED"
     gene            complement(5640..6218)
                     /gene="rsxB"
                     /locus_tag="ROH59_004270"
     CDS             complement(5640..6218)
                     /gene="rsxB"
                     /locus_tag="ROH59_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HDX4806678.1"
                     /translation="MNAIWIAVAAVSLLALAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     LTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            complement(6218..6799)
                     /gene="rsxA"
                     /locus_tag="ROH59_004271"
     CDS             complement(6218..6799)
                     /gene="rsxA"
                     /locus_tag="ROH59_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDX4806679.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(6876..7316)
                     /locus_tag="ROH59_004272"
     CDS             complement(6876..7316)
                     /locus_tag="ROH59_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707526.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HDX4806680.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            complement(7402..7617)
                     /gene="ydgT"
                     /locus_tag="ROH59_004273"
     CDS             complement(7402..7617)
                     /gene="ydgT"
                     /locus_tag="ROH59_004273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HDX4806681.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
     gene            complement(7889..8014)
                     /gene="blr"
                     /locus_tag="ROH59_004274"
     CDS             complement(7889..8014)
                     /gene="blr"
                     /locus_tag="ROH59_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HDX4806682.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSTTVQHK"
     gene            8257..9297
                     /locus_tag="ROH59_004275"
     CDS             8257..9297
                     /locus_tag="ROH59_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDX4806683.1"
                     /translation="MSDNIRVGVIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVK
                     ADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALAKTLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIELGI
                     ESAKHRATLCLA"
     gene            complement(9333..10334)
                     /gene="add"
                     /locus_tag="ROH59_004276"
     CDS             complement(9333..10334)
                     /gene="add"
                     /locus_tag="ROH59_004276"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDX4806684.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLT
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(10438..11610)
                     /gene="malY"
                     /locus_tag="ROH59_004277"
     CDS             complement(10438..11610)
                     /gene="malY"
                     /locus_tag="ROH59_004277"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000459377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HDX4806685.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLIHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDPQSVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRVYLKDNLTYIADKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKIAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVG"
     gene            complement(11620..13212)
                     /gene="malX"
                     /locus_tag="ROH59_004278"
     CDS             complement(11620..13212)
                     /gene="malX"
                     /locus_tag="ROH59_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HDX4806686.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     VGYAVMNLAVNFWLTNKGILPTMDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYIIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMVGLMRTVQA"
     gene            13387..14415
                     /gene="malI"
                     /locus_tag="ROH59_004279"
     CDS             13387..14415
                     /gene="malI"
                     /locus_tag="ROH59_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mal regulon transcriptional regulator MalI"
                     /protein_id="HDX4806687.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRIAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVIWASTPARELGTTLADRMMQKITHEETHSRNLII
                     PARLIAAK"
     gene            14527..>15139
                     /gene="hdhA"
                     /locus_tag="ROH59_004280"
     CDS             14527..>15139
                     /gene="hdhA"
                     /locus_tag="ROH59_004280"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HDX4806688.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAVSKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLIAPEMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTNALKSVITPE"
BASE COUNT         3808 a         3854 c         3916 g         3561 t
ORIGIN      
        1 tgtttttaca ttgccacagc atcgtgatct tgatcacgaa tgaatagaaa atttcgctat
       61 taaaaaaaca attaacctgc atttttggtt atctgcaaac ggattacctg atgataacgc
      121 taagcaatgg catcattgac gttaaaaaga tgttttaaaa gaggataaag aaaggttatg
      181 aatggggtaa tcggtgttac ccctgatctt tagatgtcaa ctttctcttt gtattcacaa
      241 agatcttcaa taatacaaga gccacagcga ggcttgcggg caatgcaggt ataacgcccg
      301 tgcaggatca accaatggtg gcagtcgact ttaaactctg ccggaaccac tttcagtagc
      361 ttttcttcta cctgttcgac gtttttcccc ggcgcaaatt gagtacgatt gcaaacgcgg
      421 aaaatgtgcg tgtcgacagc aatagtcggc cagccgtatg cagtgtttaa tacgacgttg
      481 gctgttttac gacctacacc aggcagggct tcaagcgcag cacgatcttc cggaacctcg
      541 ccattatgtt gttccagtaa tatacggcag gttttgatga tattttctgc tttgctgtta
      601 taaaggccaa tcgttttgat ataggttttc accccttcaa cgcccagttc aagcatcgct
      661 gcaggcgtat tagccaccgg gtagagtttc gccgtcgcct tattaacact gacatcggtc
      721 gcctgagcgg aaagcagtac ggcaatcagc aattcaaaag gcgaactgaa attaagctcg
      781 gtggtgggat gaggattgtt ctcacgcagg cgagtgagga tctccaggcg ttttgctttg
      841 ttcatcagac attccctgtt tcaccgtttg gcaatgcacg ttcggcagct gcttcagtac
      901 ggcgcttttt cattttttca tcaatcaggt attttcctgc cagcatcagt cccaggccaa
      961 taaatgcacc tggtggcagc atcgccagca ggaaagggga gtcggtgtgg aaaatctcca
     1021 cgcgtaatac ttttgcccag ctacctaaca gcgcatctgc accgtcaaac aacgtgccat
     1081 tgccgataat ttcgcgtagt gaacccagca cgaacatggc gcaggttgcg cccataccaa
     1141 ttgaaaagcc gtccagtgcc gaaagcgccg gacctttttt ggcggcgaag gcttcagcgc
     1201 ggcccacaac gatacagtta gtgacaatca gcggaataaa aatccctaat gattgataca
     1261 ggccaaaggc gtaggcgttg atcagcatct gtacagcgct gaccaccgag gcgatgatca
     1321 tcacgtaaat gggaatgcgg atctcggcgg gcgtccagtg acgcagcgtc gaaatggtca
     1381 ggttggttag cgtcagtacc agcgtagtcg caagtcctaa acccagagcg ttagtggcag
     1441 tggacgtgac cgccaacaga ggacaaaggc cgagcagctg gaccagcgca gagttgtttt
     1501 tccacaaccc ctgaacaata acgtctttaa tttcgctcac gttttattct ccacaggcag
     1561 gaagttgaga aagttgtgcc ggtaacgtct gagcgtacaa tccggcgcgt tttaccgcat
     1621 taaccaccgc gcggggagta atcgtcgcgc cagtgaactg gtcgaaatca ccaccatctt
     1681 tcttcaccgc ccagttcgca tcatccgcac cactgatttt tttacccgca aaatgggtga
     1741 tccagtcaga aaggcgcagt tcgattttat cgccaagccc tggcgtttcg tggtgctcag
     1801 tcacgcgcgt gccaagtacc gtgccgttaa aatcggctcc caccagcagc tgaatcgcac
     1861 cggaatagcc atctggcgcg gttgcttcca gaacggcagc taccggtttg tcatcctgtt
     1921 tggcgatgta aacccgatgc tcacctttac ctaactctgg cgcagttacc agatagcaac
     1981 tctgtgccag cgcattgtta tagcgttcag ctggcagcac ctgatcaaat aacgcctttt
     2041 gttgcagact ggcctgctca gcaattgtcg ttttggtcat ctggttgatg gccgcagtta
     2101 accctgttga acccgctgca aagagcgcca acgtaatgcc gtgttttcgg atagttttca
     2161 gcatggttta ccctttgcga tggccgtaga cgcgcggacg cgtgtagtaa tcgatcagag
     2221 gaaccgtgat gttcgccagc aggacggcaa aagccacgcc gtcaggatag ccgccgaaac
     2281 tgcggatcaa ccagactaat aagcccgcca gcgcgccgaa aataagacga ccacgattgg
     2341 tcgtagaagc ggtaaccggg tcagtcaaaa taaagaatgc gccgagcatg gtcgcaccag
     2401 acagcagatg aatttgcggt gctgccagag tatctggtga gaacaaccaa cccaacgttg
     2461 cgcataacgc cagcgttact aagaagctga ggggaatatg ccagcgaatc gctttctgcc
     2521 atagcaacca cacgccgcca gtcagccagg cgagatttac ccattgccaa ccagcgcccg
     2581 ccagaatacc gctgtagatc ggatattgca taatctcttc aaccgaatga ccggcacgga
     2641 cagaggtttt aaatgtatcc agcggtgtcg cctgactaat gccatcaata cctaagcgta
     2701 gcgtgttcat atcaccacca ctggtggtat gtccgctgaa aataacctgt atggcgtcga
     2761 taaaaccagg gatgttgacc gcaatttcat gtggcggtaa ccagctggtc atctgcaccg
     2821 ggaaggagat cagtaagacc acataaccaa tcattgccgg attaaacggg ttttgcccca
     2881 gaccgccata caactgttta gcgatgatca ccgcaaacac cgtacccagc acgaccatcc
     2941 accatggcgc gaggggggga atacttaccg ccagcaataa gcctgtcagc aatgctgagt
     3001 tatctttcaa cgttgcagct accgactgct tgcgtagttt gaggacgaga gcttcggcca
     3061 gaagagcact gaccgacgcc aacaggatct gaacgagagt accccaacca aaaaaccaca
     3121 gttgcgctgc gattcctggc acggctgcga gcaataccaa catcataatg cgcgatgtct
     3181 ggcgctggtt atgggtataa ggggagctag ctattctgaa taccatttag tcctcgttta
     3241 caaccttttg ctgggcggct tttttggcct gaacgcgggc aatagccgca gcaactgccg
     3301 ctttgcgcgg atcaatctgt tcttctggct ctgcattagc ctgttgctgt tccagcttgc
     3361 gtgctttggc acgggcaata gcagcttcga cggcggcttt gcgtggatca acctgttctt
     3421 ctggttccgc attagcctgt tgttgctgtt ccagcttgcg cgctttggcg cgtgcaatag
     3481 ccgcttcgac ggcagctttg cgcggatcga cctgttgttc tggctccgca ttggcctgtt
     3541 gctgttccag cttgcgtgct ttggcgcggg cgatagcggc ttcgacggcg gctttgcgtg
     3601 gatcaacctg ttcttctggt tccgcattag cctgttgttg ctgttccagc ttgcgtgctt
     3661 tggcacgggc aatagcagct tcgacggcgg ctttgcgtgg atcaacctgt tcttctggtt
     3721 ccgcattggc ctgttgctgt tccagcttgc gcgctttggc gcgtgcaata gccgcttcga
     3781 cggcagcttt gcgcggatcg acctgttgtt ctggttcggc attagcctgt tgctgttcca
     3841 gcttgcgtgc tttggcacgg gcaatagcgg cttcgacggc ggctttgcgc ggatcaacct
     3901 gttgttctgg ctccgcattg gcctgttgct gctccagctt gcgtgctttg gcgcgggcaa
     3961 tagccgcttc aacggcagtt ttacgtggat cagcaacggt tgcagcgtcg ttagtttgct
     4021 gcagttctgc ctgtttcgct ctggcttgcg ctttacgggc ttcccgtgct gcaataattg
     4081 cactgttatc cgggcgttcg cccgctttaa tcacaatagg ctgtgtagcc tgggcctgtt
     4141 tctctttcac ccgcgccaga gcggcagcaa tcgcatcttt atctttggct gcaggttgaa
     4201 cggctgcgct cttatgtcgt tcaaggcgag ccgttttttc gcgctccaga cgagcctggc
     4261 gcgcttcgaa acgcgctttg gcttctgcgg cgcgcttttc ttcctgacga atagccgcaa
     4321 tttcagcttt ttcctgacgg aaatattgca ccagggggat attgctcggg caaacccacg
     4381 cgcaagcccc acattcaatg cagtcggcaa tgttatgcgt ggtggcttta tcgtgttgct
     4441 gacctttgct gaaccagtac agctgttgcg gcaaaagatc cgcagggcag gcgtcagcac
     4501 aggcgctaca acggatgcaa ctttgttctt cctgtggttc gccaagttca ttggcagagg
     4561 gagccaaaag acagttggta atctttacga ccgggacatc cagccacggt aaggtaaagc
     4621 ccattagcgg gccgcccata atcaccattt gatcggcaga ggggcagaat ccggcatcat
     4681 tcaataaatg acgcactggc gtacccagcc gtgcccagac gttgcccggg cgagcgattg
     4741 cttcgccagt cagggtcacg acacgctcgg taatcggctc gccatcaata acggcacgtt
     4801 tcactgcata agcggtgccg acgttttgca ttaatacgcc gatatcggat gaacgcccgc
     4861 catgtggaac ctgcttcccg gtcagaatgt aggttaattg tttagcaccg ccagaaggat
     4921 atttggtggg aatcacccgc agagaaatat cgtgggagtc cgccagcacc gcgcgtagca
     4981 tggaaatcgc ctgcggtttg ttatcttcaa tgccgataag aatttcgcgc ggctgcagaa
     5041 tatgcgcaag gatgcggata ccctctacga cctgagccgc gcaatcctgc atcaaacggt
     5101 catcggcggt aatgtacggc tcgcactcag cagcgttgat aatcaacgtt tcaatcttat
     5161 ctccgccgcc ctgcaattta acgcctgtcg gaaatcccgc accacccagc ccggcaacac
     5221 caaactgatg aatgcgctcg attaactctt cgcgactgcg agagcgataa tcggcccagc
     5281 cgtcgcgcgg gatccagcag tcttcgccat cggcatcaat aatcacactt aattcagcta
     5341 aagctgaagg atgagccgta gagtggggcg caatagccgt aacggtaccc gaggtgggcg
     5401 cgtgaaccgg cagcattttg ccgcgaccac gggtaagcgg ctggccgcgc aatactttat
     5461 cgccgacgct aacgcacaac tcaccttcag cgccaatatg ttgttttagt ggaatgacaa
     5521 aacgctgcgc cagtggtacc tggcgcaggg gcgtaccgtt ggactgggtt ttcatctccg
     5581 gtggatggat gccgccgttg aaatcccaga ttttattttt tctgaatgca gagaataact
     5641 taagcatggt gttccacggg aatgatacgc acgggaatgg tgttcagatc ccatttccag
     5701 gagtcaggag tttctgcgac cggttgcaac gagatgcagt gcgtcgggca cggatcaaca
     5761 cataaattgc agcccgtaca gagatcactc attaccgtat gcatggcgcg ggtagcgcca
     5821 acgatggcgt ctaccggaca cgcctgaata catttagtgc agccaataca gttattttca
     5881 tcaataaccg ccaccatccg cgctggcgtt agctcttgcg cttcgccatc cagcggctgc
     5941 ggctcgacat taagcaactc ggcaattttt agcatcacag cttcgccacc tggggcgcaa
     6001 cggttgattt tttcaccgtt acagctgatg gcttccgcgt aggggcgaca gccgggataa
     6061 ccgcactgac cacactggct ctgcggtaag atttcgtcaa ttttctcaac gaccggatcg
     6121 tcttccaccg caaaacggcg ggaggcataa cccagaatgg cgccaaacgc cagggccagc
     6181 aggctcacgg cggcaacggc aatccagata gcattcatta caacttcacc aaaccactaa
     6241 agcccataaa ggccagagac ataagacctg cggtaattaa cgcaatggca ttaccgcgaa
     6301 aaggtgccgg gacatcagcc acagcaaggc gttcgcggat ggcggcgaag agcaccatca
     6361 ccagcgagaa accgacagcg gcggaaaaac cgtacagcgc tgactgcaag aaattgtgcc
     6421 cgagattgat attcagcaac gccacgccga gcacggcaca gttggtggtg ataagcggca
     6481 aaaaaatccc cagcagacgg taaagtaccg ggctggtttt gcgcaccacc atttcggtga
     6541 actgcacaac cacagcaatc accagaataa acgccagggt gcgcagataa atcagattaa
     6601 gtgggatcaa aatccacgta tcgataagcc aggcgcaaat agacgccagc gtcattacaa
     6661 acgttgttgc cagccccatg cccatcgcgg tttccagctt tttggaaacc cccataaacg
     6721 gacagagacc gagaaacttg accagtacaa agttattgac cagtacagtt ccgacaaaca
     6781 gtaacaggta gtcagtcatt tttcggcctg aaataaaaaa gccgcctatt atccgttaat
     6841 ccagagcagg cgacaacagg ttaactgtaa ggttattacg gattcacaaa cgtcgctttc
     6901 acccgcgacg agcgtttgaa ataggggacg atcaatgcgg ttgccaacaa agtaaacagc
     6961 aactggcgaa cggctatgcc atcttctacg ggtgaaaaag cgaacgcttt tactgccagc
     7021 aatacggaaa taagcagcca gataatatag tgtttaggaa cacaacgccg acgtttaaag
     7081 aaagcgatgg tcaaccacag tgtgtaatac cacatggcga tagcggtaat aaaagaaacg
     7141 ccccataaga tttgtgtcgt cagtgcttgt ccgccgagcg tttgaaatgt ttgcggagaa
     7201 gataacgcag cggtatacag caacaacgcc agcgtcgtac tcaacagagc gactaaaagc
     7261 caggccaacg ggccaagcaa ccagcctcca atacgttgtg gcgttgtggt ggtcataggt
     7321 tctccagaat agcgacgcaa acagacaaat ctaattttag gggcgttatt ataaggcttt
     7381 tataaccgat cgctactttc tttactggac atagtgccag acggacttcg gtacctggcc
     7441 gaggtcaaac aaacgcccgc cagaaaccag ctctgcgcga cggtgatcgg cagcacgata
     7501 catattgatc agttcctgat cgtccgtcag ggtgtaatta agatggtcgt agagtttttc
     7561 cagactttcg agtgaactga ttttgcgaaa ttttaataag tagtcctgaa cagtcataaa
     7621 aggtccataa ataattaata ccaaaggggt aggtattatt agtgatgata aaatttcacc
     7681 aaaagtgaac gcttgtgtta ttacaataat aagaatgcgc tgatggcaaa tattcaggga
     7741 tgaaaaactg ctctgaaaag agtaacgcgc tttactatcc ctgacaatca tcaacaacat
     7801 cgaacaagat aataaattcc tggtttaata tccgacaagt gaaaacatgc acccggacgg
     7861 gcagcatgtc gctcaacaag tgcagagctt acttgtgttg taccgtagta ctctgttcag
     7921 gtggctgata gttgtcaatg tgactcgcca cgccaagaag aatgactgaa acgacaagaa
     7981 cgatccaacc tgttaattca ataagacgat tcattacagc ccacatctct gttgattgat
     8041 ccattaactt cagggggtaa atgttactta gcaataatag ctccagcaag atttttactg
     8101 aggtttttgc gatatttagc ttttgtcgtt ggaaaaatcg ctattttttt gacttaagtt
     8161 aaacaacatc ccttattgct ggcaggttat taaactgttg agcgagggta aaggatagtg
     8221 tcaaatagcc atcatacttc aatgagaggc aatgacatga gcgacaacat ccgtgttggg
     8281 gtgattgggt atggttatgc gagcaaaacc ttccatgcgc ccctgattgc gggcacgccc
     8341 gggctggaac tggcggtaat ctccagcagc gatgaaacaa aagtaaaagc cgactggcca
     8401 acggttacgg ttgtctctga gccgaagcat ctgtttaacg atcccaacat agacctgatt
     8461 gtcattccta cacccaacga tacccatttt ccgttagcta aagcggcgct tgaggcgggt
     8521 aaacatgtgg tcgttgataa accctttacc gtgacactgt cacaagcacg agagctggat
     8581 gcgctggcaa aaaccctggg gcgtgtgttg tctgtattcc ataaccgtcg ctgggatagc
     8641 gattttctga ccctaaaagg tttgctcgcg gaaggcgtgc tgggggaagt tgcttacttt
     8701 gagtctcatt ttgaccgctt ccgtccgcag gtacgcgatc gttggcgtga acagggcggc
     8761 ccaggcagcg gtatctggta cgatttagca ccgcaccttc ttgatcaggc cattacgcta
     8821 tttggtttac cggttagcat gacggtagat ttggcacagt tacggcccgg agcgcagtcg
     8881 accgattatt tccacgctat cttgtcctat ccgcagcggc gagtgatttt acacggcacc
     8941 atgctggcag ccgctgagtc agcacggtat atcgtgcatg gatcccgagg cagttatgtg
     9001 aaatatggcc tcgatccaca ggaagaacgt ctgaaaaatg gcgagcgtct gccgcaggaa
     9061 gactggggct acgatatgcg tgatggcgta cttacccgcg tggaaggtga ggaacgtgtc
     9121 gaagaaacgc tgttgacagt gccggggaat tatccggctt actatgcggc tattcgtgat
     9181 gcgttaaatg gcgatggtga aaatccggtt ccggcaagtc aggcaatcca ggtaatggag
     9241 ttgattgagc tgggcatcga atccgccaaa catcgcgcga ctttgtgcct tgcgtgaaaa
     9301 ggggatggtg caattagcac catccatttt tgttacttcg cggcgacttt ttctcgcagt
     9361 gcgcgttttt cctctgcgct gaggaaagcc atttccagac cattaatctg tgcctggcgg
     9421 atttgctcgc gggataaccc agcagctggc gcggcaacgg tatattcgtg aatgatatcc
     9481 actccctgca cgccgggatc gtcagtgtta atgctggcac gaatgccatg ctcaaggaac
     9541 gttttcagcg gatgtgcagc cagatccgcc acggtgctgg tctgaatatt ggaggtcaga
     9601 caggattcaa taccaatttg ttgctcggcg agaaaatcca tcagcgcccg atcttcaatg
     9661 gcttttacgc catgtccaat acgctccgcc cccagttcac gaatcgcctg ccagatgctt
     9721 tccggtccgg cagcttcgcc tgcatggacg gtaatatgcc agcccgcatc acgcgcgcgg
     9781 ttgaaatgag aaaggaacag acttcccggg aaaccaagtt catcaccggc taaatcaagt
     9841 gcggtaatct ggtcacggtg ggctaaaaag gcctccagct cttgctgaca ggcggcttcg
     9901 ccgaaggtcc ggctcataat accgataagc ttcgcctgca caccaaaggt gcggcaacct
     9961 tcacgtacgc catcgatcac cgcttcgaca acacccgcta caggcagctg atgtgccatt
    10021 gccatgtagc ctggtgaaaa acgcagttcg acatagtgca ggccgttacg ggctgcatct
    10081 tcaatgtttt caaatgccac gcggcggcag gcatcaagag aggcgagaac tttaacgccc
    10141 cagtcaagtt tagtcagaaa gctcaccaga tcgggttcgt tggcaatgac ctgaacgtgg
    10201 ggagtcagtg tttccaggga ttgtgcagga agcgagatat tatactggcg gccaagttca
    10261 agaatggtct ggggacgaat gttgccatca aggtggcgat ggatatcagt taatggcagg
    10321 gtggtatcaa tcatggtcgc actctttttc tggatataaa agtgcgcacc attataaaaa
    10381 caaagcaggg taaaaatcca cgattgcgca acgatttttt acgttgcgca attggggtta
    10441 accaacagcg cggatggcgt taattaatcc agccacacct ttttccagtt tcgaacgtgg
    10501 gcagccggca ttgagtcgga caaaaccacg accttcttca ccgtaggtat atcccggcat
    10561 gatcgcgatc ttttcttgct cgataagcgc tttttgcaac gcgttgtcgt caatattcaa
    10621 cggacgtaga tcaagccagg ccagataagt ggattgcggg atctgccagt tgagttcagg
    10681 aaacgcagcg ttcattttat ctgcgatata cgtcaggtta tctttcagat agacgcgtaa
    10741 ggcatccagc catggcgcgc cttgctgata ggcggcgata tgagcagtta acgccagtac
    10801 cgaaggggaa gaaagcccat cacgtccttt cagtgccgat aaataggcat cgcggctact
    10861 gctattttct ataatcccgt aagcaccggt cagggcggga atattgaaac tttttgatcc
    10921 cgacgttagc aacgcccagt ctccgcgcgc cacattactc cagggaatat gcggctgctc
    10981 gccccaaacc atatccatat ggatttcatc ggaaataacc cgcacaccat gacgctcgca
    11041 caggtcagcc atgatctcca gctcatcgca cgtccacact ttcccggtag gattctgtgg
    11101 gctacacagg agcataattt tacattctgg tttcgccagc acggcttcca gcttgcccat
    11161 atcgcaaaac cagccgtcag cctgcttctc taaagcaacg ggcattactg tgcgctggtt
    11221 accttcaatg gccttgtaaa atgcgtcata ggcgggtgtg tggatcacca cgccttcacc
    11281 tgtttcagac cactgacgaa tcagttctga aaccatatag ataacagaag ggccatacac
    11341 caccgactga ggatcgatgg cggtgtaatg ctgggtggaa aaccagtggg caatagccgc
    11401 gagaaactca tcgtttttcc agcggctgta gccaaacacg ccgtgtatca ggcgctgatt
    11461 cagcgcctcg ataatgcagg gggcagtggc aaaatccatg tctgaaatcg tgaacggtaa
    11521 caggtcagca gtgccgaaac ggtcagcgac ataatcccac tgcgtacacc atgtgccatg
    11581 acgatccacg acctttgaaa aatcgaacat atcttatcct tatgcctgga cagtacgcat
    11641 cagaccgacc atttcatctt ttactgactg aacttgtggc ccgataacaa cctgcaggtt
    11701 atgttgatta agttgtacta cgccaattgc ccgattgtcc ttcagtgcct gcacattaac
    11761 aagcgacata tcttttacag acaaacgcag acgcgtaatg cagttatcga gactgacaat
    11821 attgtcggca ccgcctaagg cttcgaggat tgccggaacg ttgtaacctg atttacccgg
    11881 cgcaccggca acggcttttt cgattgaact ggcaacttca ctatcgcgcc ccggggtttt
    11941 gagattgaag cgggtgatag cgaaacggaa gatgatgtag taaacgacaa accagattgc
    12001 cgccactact ggcaccatgt accacttggt tgacagacca tgcaaaatac cgaacaccac
    12061 aaagtcgatg atattgccgt cggtattacc gatggtgacg ccgagcacag acatgacagt
    12121 gaagccgagg ccggttaaca gcgcgtggat gacatacaga actggcgcta cgaacaggaa
    12181 caggaattcc agaggttcgg tcgtgccgcc aacgacacag gcgatcaggc cagaaatcag
    12241 cagaccttta attttatggc gattttccgg gcgcgcacag tgatacatag ctaacgctgc
    12301 acctggcaga ccgccgagaa acgcaggcat tttaccttgc gaaaggaaac gcgtggcgct
    12361 ttcagaaaaa ccgtgagtgg tcgggcaact caattgcgcc tggaagatgg tcagtgcacc
    12421 gctgacggtt tgaccgcaga cttcctgcgt gccgcctgcg tcggtaaagc gaattaatgc
    12481 caccagaatg tgatgcagac caaacggcaa cagcagacgt tcaccggtac caaacagcat
    12541 cggtccgaaa tcacccgcgc tgttgatcat atggcctaag ccgctaatac ccatggcgaa
    12601 aatcggccag actaatggaa tcaccaggcc gacaagaccc atcaccagcg aggagatgat
    12661 tggtacgaag cgcgtaccgc cgaagaatgc cagcgcatcc ggcaggcgga tattatggaa
    12721 tcgctcatgc agcatccaga cgataatacc ggcgatcacc gcaccgagga tcccggtgtc
    12781 gatcgactgg atcccaagaa tgctctggat gttattggct ttcagaacgg cggcgtccat
    12841 ggttggcaga atgcctttat tggtcaacca gaagtttacc gcgaggttca ttaccgcata
    12901 accgacgaag ccagcgaatg ccgctacgcc tttgttttcg cgtgccagac ccagcgggat
    12961 ggcgatacag aacatgactg gcaggaaact aaaagcaaac gagccaatct tactcatcca
    13021 ggtaaagata gcctgcaaca cggggttgcc caggaccggg atcagggtga tgacatcatg
    13081 gctgctaaga gaactaccaa tgccgagcat aatgccgcag aacgacaata atgccacggg
    13141 taacatgaag gttttgccta actgctggaa gaactcccac agcgtgactt tcggtgctgt
    13201 tttcgccgtc ataaaacgac tcctcgtaga gaacaatctg gattcagtaa attgcgcgag
    13261 aagataaaac gttttatcaa attttagtga ggcataaatc acattacgca acgataatag
    13321 cgggtataag ataaataaaa ggtaaaacgt tttatctgtc acataatcag ggagtaggtc
    13381 atctgcatgg ctaccgccaa aaaaataacc attcatgatg ttgcgctggc tgcgggcgtg
    13441 tcggtaagta ccgtttcgct ggtgcttagt ggcaaagggc gaatctctac cgccacagga
    13501 gaacgcgtta acgccgccat tgaagagctg ggatttgtgc gcaatcggca ggcgtcggcg
    13561 ctgcgcggcg ggcaaagtgg cgtcattggt ttgatcgtcc gtgatttatc tgcgccgttt
    13621 tacgccgaat tgacggccgg attgacggaa gctctggaag cgcagggacg gatggttttt
    13681 ttgcttcacg gcggtaaaga cggcgagcag ctggcacagc ggttttcact attactgaat
    13741 cagggtgtcg atggtgtggt aattgccggg gctgcaggaa gcagcgatga cctgcgacgg
    13801 atagcagaag aaaaagctat cccggtgatt ttcgcttccc gtgccagtta tcttgatgac
    13861 gttgatacgg ttcgcccgga caacatgcag gctgcacagt tgttgacgga gcatctcatt
    13921 cgcaatgggc atcagcgtat cgcctggctg ggagggcaaa gttcctcatt aacccgggca
    13981 gaacgggtgg ggggctattg tgcgactcta ctaaaatttg gcctgccgtt tcacagcgat
    14041 tgggtgctgg agtgcacttc cagccagaag caagccgcgg aagctatcac ggcgctttta
    14101 cgtcataacc cgaccatcag cgccgtggtt tgctataacg aaactattgc gatgggggca
    14161 tggtttggtt tgctgaaagc aggaaggcaa agcggggaaa gcggagtcga tcgttacttt
    14221 gagcaacagg tttcgctggc ggcatttacc gatgcaacgc ctaccacact tgatgatata
    14281 cccgttatct gggccagcac gccagcgcgg gaacttggta ccacacttgc ggatcgcatg
    14341 atgcaaaaaa tcacccatga agagacgcat tcacgcaatc ttattattcc cgcccggctc
    14401 attgcggcga aataatcctc tctttatctg ctatacctgg tagtgtcctt tcctcaaggt
    14461 taatgataaa aaatgtggca cacaggcggt gccttttatt tttactgaag ttcacaggag
    14521 gtttatgtgt ttaattctga caacctgaga ctcgacggaa aatgcgccat cattacaggt
    14581 gcgggtgcag gtattggtaa agaaatcgcc attacattcg cgacagctgg cgcatctgtg
    14641 gtggtcagtg atattaacgc cgatgcagct aatcatgttg tagatgaaat tcaacaactg
    14701 ggtggtcagg catttgcctg ccgctgcgat attacttccg aacaggaact ctctgcactg
    14761 gcagactttg ccgtcagtaa gttgggtaaa gttgatatcc tggttaacaa cgccggtggc
    14821 ggtgggccta aaccgtttga tatgccaatg gcagattttc gccgcgctta tgaactgaat
    14881 gtattttctt ttttccatct gtcacaactt attgcgccag aaatggaaaa aaatggcggt
    14941 ggcgttattc tgaccattac ttctatggcg gcagaaaata aaaatataaa catgacctcc
    15001 tatgcatcat ctaaagctgc ggccagtcat ctggtcagaa atatggcgtt tgacctgggt
    15061 gaaaaaaata ttcgggtgaa tggcattgcg ccgggggcaa tattaaccaa tgccctgaaa
    15121 tccgttatta ccccagaaa
//
LOCUS       DAPOXO010000106        14736 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.106, whole genome shotgun sequence.
ACCESSION   DAPOXO010000106 DAPOXO010000000
VERSION     DAPOXO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14736
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.106"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(344..1537)
                     /locus_tag="ROH59_004281"
     CDS             complement(344..1537)
                     /locus_tag="ROH59_004281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4806689.1"
                     /translation="MSPGIEDTPQKPLSCWPLAFSAGLLGIGQNGLLVVLPVLVIQTN
                     LSLSVWAALLMLGSMLFLPSSPCWGKQISRTGSKPVVLWALGGYGISFTLLGLGSVLM
                     ATSAITTAVGLGILIIARIAYGLTVSAMVPACQVWALQRAGEGNRMAALATISSGLSC
                     GRLFGPLCAAAMLAIHPLAPLGLLMAAPVLALLMLLRLPGTPPQPTPECKSVSLKRDC
                     LPYLLCAILLAAAVSMMQLGLSPALTRQFATDTTAISQQVAWLLGLSAVAALIAQFGV
                     LRPQRLTPVALLLSAGVLMSGGLAIMLSEQLWLFYPGCAVLSFGAALATPAYQLLLND
                     KLADGAGAGWLATSHTLGYGLCALLVPLVSKTGVAIALIMAALFATILFTIVSVFIWH
                     YRTIK"
     gene            1673..3397
                     /gene="iucA"
                     /locus_tag="ROH59_004282"
     CDS             1673..3397
                     /gene="iucA"
                     /locus_tag="ROH59_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucA"
                     /protein_id="HDX4806690.1"
                     /translation="MTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDE
                     QKSLHFRVAYFSPTQHHRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLC
                     ETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFN
                     RREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDN
                     QWLFPLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIK
                     FSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTFRVMQEDGWAGLRDL
                     NGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITV
                     QQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSA
                     FMPHATDWLDSIGEAQAENIFTHEQLLRYFPYYLLVNSTFAVTAALGAAGLDSESNLM
                     ARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFA
                     NPLQAQEV"
     gene            3398..4345
                     /gene="iucB"
                     /locus_tag="ROH59_004283"
     CDS             3398..4345
                     /gene="iucB"
                     /locus_tag="ROH59_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(6)-hydroxylysine O-acetyltransferase"
                     /protein_id="HDX4806691.1"
                     /translation="MSEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGW
                     LCDALDQIFIAAPQLSAVALPWAEWREEPQALTLFGQVKSDIIHRTAFWQLPLWLSSP
                     ANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
                     MNDPRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIG
                     RHYSWQPFDRGLHLLVGEQQWRGAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNLR
                     LFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL"
     gene            4345..6087
                     /gene="iucC"
                     /locus_tag="ROH59_004284"
     CDS             4345..6087
                     /gene="iucC"
                     /locus_tag="ROH59_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucC"
                     /protein_id="HDX4806692.1"
                     /translation="MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGA
                     QWRFIAERGIWGWLWIDAQTLRCTDEPVLAQTLLMQLKPVLSMSDATVAEHMQDLYAT
                     LLGDLQLLKARRGLSASDLINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
                     TNTFRLHWLAVKREHMIWRCDNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPL
                     PVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPL
                     TIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYA
                     ALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLD
                     AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLV
                     KEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQ
                     LLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLED
                     LQNPLWLVTQEYES"
     gene            6084..7361
                     /gene="iucD"
                     /locus_tag="ROH59_004285"
     CDS             6084..7361
                     /gene="iucD"
                     /locus_tag="ROH59_004285"
                     /EC_number="1.14.13.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent L-lysine N(6)-monooxygenase"
                     /protein_id="HDX4806693.1"
                     /translation="MKKSVDFIGVGTGPFNLSIAALSHQIEELDCLFFDEHPHFSWHP
                     GMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKHKKFYRFLTSRLRTVSREEFSDY
                     LRWAAEDMNNLYFSHTVENIDFDKKRRLFLVQTSQGEYFARNICLGTGKQPYLPPCVK
                     HMTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRN
                     NFNALDEAAFADEYFTPEYISGFSGLEEDIRHQLLDEQKMTSDGITADSLLTIYRELY
                     HRFEVLRKPRNIRLLPSRSVTTLESSGPGWKLLMEHHLDQGRESLESDVVIFATGYRS
                     ALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFVVNASMQTHGIAEPQLSL
                     MAWRSARILNRVMGRDLFDLSMPPALIQWRSGT"
     gene            7443..9644
                     /gene="iutA"
                     /locus_tag="ROH59_004286"
     CDS             7443..9644
                     /gene="iutA"
                     /locus_tag="ROH59_004286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric aerobactin receptor IutA"
                     /protein_id="HDX4806694.1"
                     /translation="MMISKKYTLWALNPLLLTMMAPAVAQQTDDETFVVSANRSNRTV
                     AEMAQTTWVIENAELEQQIQGGKELKDALAQLIPGLDVSSRSRTNYGMNVRGRPLVVL
                     VDGVRLNSSRTDSRQLDSIDPFNIDHIEVISGATSLYGGGSTGGLINIVTKKGQPETM
                     MEFEAGTKSGFSSSKDHDERIAGAVSGGNEHISGRLSVAYQKFGGWFDGNGDATLLDN
                     TQTGLQYSDRLDIMGTGTLNIDESRQLQLITQYYKSQGDDDYGLNLGKGFSAIRGTST
                     PFVSNGLNSDRIPGTERHLISLQYSDSAFLGQELVGQVYYRDESLRFYPFPTVNANKQ
                     VTAFSSSQQDTDQYGMKLTLNSKPMDGWQITWGLDADHERFTSNQMFFDLAQASASGG
                     LNNKKIYTTGRYPSYDITNLAAFLQSDYDINNLFTLNGGVRYQYTENKIDDFIGYAQQ
                     RQIAAGKATSADAIPGGSVDYDNFLFNAGLLMHITERQQAWLNFSQGVELPDPGKYYG
                     RGIYGAAVNGHLPLTKSVNVSDSKLEGVKVDSYELGWRFTGNNLRTQIAAYYSISDKS
                     VVANKDLTISVVDDKRRIYGVEGAVDYLIPDTDWSTGVNFNVLKTESKVNGTWQKYDV
                     KTASPSKATAYIGWAPDPWSLRVQSTTSFDVSDAQGYKVDGYTTVDLLGSYQLPVGTL
                     SFSIENLFDRDYTTVWGQRAPLYYSPGYGPASLYDYKGRGRTFGLNYSVLF"
     gene            complement(10195..10338)
                     /locus_tag="ROH59_004287"
     CDS             complement(10195..10338)
                     /locus_tag="ROH59_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001421454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806695.1"
                     /translation="MEHRSVIHDELAIDHDAILQCAEEVLHRCVIQTVSFVRHILCYS
                     MGL"
     gene            10588..14475
                     /gene="sat"
                     /locus_tag="ROH59_004288"
     CDS             10588..14475
                     /gene="sat"
                     /locus_tag="ROH59_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease autotransporter toxin Sat"
                     /protein_id="HDX4806696.1"
                     /translation="MNKIYSLKYSAATGGLIAVSELAKRVSGKTNRKLVATMLSLAVA
                     GTVNAANIDISNVWARDYLDLAQNKGIFQPGATDVTITLKNGDKFSFHNLSIPDFSGA
                     AASGAATAIGGSYSVTVAHNKKNPQAAETQVYAQSSYKVVDRRNSNDFEIQRLNKFVV
                     ETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFINGESKISTNSAY
                     SHDLLSASLFEVTQWDSYGMMIYKNDKTFRNLEIFGDSGSGAYLYDNKLEKWVLVGTT
                     HGIASVNGDQLTWITKYNDKLVSELKDTYSHKINLNGNNVTIKNTDITLHQNNADTTG
                     TQEKITKDKDIVFTNGGNVLFKDNLDFGSGGIIFDEGHEYNINGQGFTFKGAGIDIGK
                     ESIVNWNALYSSDDVLHKIGPGTLNVQKKQGANIKIGEGNVILNEEGTFNNIYLASGN
                     GKVILNKDNSLGNDQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTTKEA
                     VLAINNEDSYIYHGNINGNIKLTHNINSQDKKTNAKLILDGSVNTKNDVEVSNASLTM
                     QGHATEHAIFRSTANHCSLVFLCGTDWVTVLKETESSYNKKFNSDHKSNNQQTSFDQP
                     DWKTGVFKFDTLHLNNADFSISRNANVEGNISANKSAITIGDKNAYIDNLAGKNITNN
                     GFDFKQTISTNLSIGETKFTGGITAHNSQIAIGDQAVVTLNGATFLNNTPISIDKGAK
                     VIAQNSMFTTKGIDISGELTMMGIPEQNSKTVTPGLHYAADGFRLSGGNANFIARNMA
                     SVTGNIYADDAATITLGQPETETPTISSAYQAWAETLLYGFDTAYRGAITAPKATVSM
                     NNAIWHLNSQSSINRLETKDSMVRFTGDNGKFTTLTVDNLTIDDSAFVLRANLAQADQ
                     LVVNKSLSGKNNLLLVDFIEKNGNSNGLNIDLVSAPKGTAVDVFKATTRSIGFSDVTP
                     VIEQKNDTDKATWTLIGYKSVANADAAKKATLLMSGGYKAFLAEVNNLNKRMGDLRDI
                     NGESGAWARIMSGTGSAGGGFSDNYTHVQVGADNKHELDGLDLFTGVTMTYTDSHAGS
                     DAFSGETKSVGAGLYASAMFESGAYIDLIGKYVHHDNEYTATFAGLGTRDYSSHSWYA
                     GAEVGYRYHVTDSAWIEPQAELVYGAVSGKQFSWKDQGMNLTMKDKDFNPLIGRTGVD
                     VGKSFSGKDWKVTARAGLGYQFDLFANGETVLRDASGEKRIKGEKDGRMLMNVGLNAE
                     IRDNLRFGLEFEKSAFGKYNVDNAINANFRYSF"
BASE COUNT         3898 a         3602 c         3668 g         3568 t
ORIGIN      
        1 aaccactgaa gcaccacagc agaaattcgg gtcccctaca ctgattacag cgccccctct
       61 gctgcctatt aactcaagca cctcccaaca acttacggaa acttaattct aatacagctg
      121 taattcagtt gtgtcgtggt cggccgcggt tacttttttc gggaagtctg ctacgcatca
      181 gaataatacc gtgttctttc tgatcctgtt tagccaggta gctaagggcg taacgtaaac
      241 caggcggggg cagcaagcca gaacactgcc tgacatgttt tcatcagacg caggtcctct
      301 ctcatatcct ctgatttact ccagtaaggt gatgatcata tctttatttg atagtacggt
      361 aatgccagat aaatacagac acaatggtaa ataatatagt tgcaaataat gctgccataa
      421 tcagcgcgat tgcgacacct gttttcgata ccagcggcac cagcaaagcg cacagtccat
      481 agccaagtgt gtgactggta gcgagccagc ccgcgcctgc gccatcagcc agcttatcat
      541 tcagtagaag ttgataagcg ggtgttgcca gagctgctcc aaatgacagc actgcacagc
      601 ccgggtaaaa caaccatagc tgttcggaga gcatgatagc cagaccacca ctcatcaaca
      661 ctccggcact caggagcagg gccaccggag tcaggcgctg cggacggagt accccgaact
      721 gcgcgataag cgcagctact gcggacagac ccaacagcca ggccacctgt tggctaatgg
      781 cggtggtatc cgtggcgaac tggcgagtaa gggcaggcga aagtccaagc tgcatcatgc
      841 tcaccgccgc agccagtaat attgcgcaaa gcagataagg cagacaatcc cgcttcagac
      901 tgacgctctt gcactccggt gtgggctgtg gtggtgtgcc gggcaaccgc agcagcatca
      961 gcagcgccag cactggggct gccatcagca gccccagtgg cgccagagga tgaatggcca
     1021 gcattgctgc cgcgcacagc ggcccgaata gcctgccgca actcaggccg gagctgatgg
     1081 ttgccagagc ggccatgcga ttcccttctc cagctctctg caatgcccag acctgacagg
     1141 ctggcaccat tgccgacacg gtcagcccgt aggcgatccg ggcgatgatt aatattccca
     1201 gtcccaccgc tgttgttatg gcgctggtag ccatcagcac gcttcccagc cctagcaggg
     1261 taaagcttat gccatatcct cccagagccc acaacaccac aggtttactg ccagtacggg
     1321 aaatttgctt tccccagcac ggggacgatg gcagaaacag cattgagcca agcatcagca
     1381 gggcagccca tacagacaga ctcagatttg tctgtatgac cagaacaggg agcacaacca
     1441 gcagaccgtt ctgtccgata ccgagaagcc cggcactgaa cgcaagtggc cagcaggaca
     1501 gtggtttttg gggcgtatct tcgatccctg gtgacattat aatgtttcaa ctccatgtat
     1561 taattgtgtt tatttgtaaa attaatttat ctgacaataa catttattat tgataatgag
     1621 aatcattatt gacataattg ttattatttt gctgtgtggg agctgtttga ctatgaccct
     1681 gccctctgaa aaaccagcca cagatgtggc tgcgcagtgc ttcctgaatg cactgattcg
     1741 tgaaaccaca gactggaaac tgacagaata cccgccagac gaattgctca tcccgctgga
     1801 tgagcagaaa tcgctccatt tcagagtggc ttatttctcc ccaacccagc atcaccgctt
     1861 tgcatttcct gcacgtctgg tcacggcatc aggcagttat cctgtcgact ttaccactct
     1921 ctcccggctt attattgata agctacgcca tcaactgttt ctgcccgttc ccctctgcga
     1981 aactttccac cagcgcgtgc tggaaagcca tgtccatacg caacaggcaa ttgatgcccg
     2041 tcatgactgg gccgctctgc gtgaaaaagc gttgaatttt ggcgaggctg agcaggcgct
     2101 gctgacagga cacgctttcc accctgcgcc taagtctcat gaaccgttta accggcggga
     2161 ggctgaacgc tacctgcctg atatggcacc ccacttccca ctgcggtggt tttcggtgga
     2221 taaaacgcaa atcgccggtg aaagtttgca tctcaacctt caacagcggc tgacgcgatt
     2281 tgccgcagag aatgcgcctc agttactcaa cgaattaagt gacaaccaat ggctgttccc
     2341 gttgcacccg tggcaggggg aatatctttt gcagcagggg tggtgccagg cacttgttgc
     2401 taaagggctg attaaagact taggtgaggc cggcacgtcg tggctgccga ccacctcttc
     2461 ccgttccctc tactgtgcca ccagccgcga tatgatcaag ttctccctga gcgtacggct
     2521 gaccaactcc atccgtactc tgtccgtgaa agaagtgaag cgtgggatgc gcctggcacg
     2581 cctggctcaa accgacggct ggcagatgct acaggtccgc ttcccgactt tccgggtaat
     2641 gcaggaggat ggctgggccg ggctgcgcga tcttaacggc aacatcatgc aggaaagtct
     2701 gtttgccctg cgtgaaaatc tgctggtgga tcagccgaaa agccagacta acgtactggt
     2761 ctccctgact caggccgcac ctgatggcgg tgattcgctg ctggtttcgg cggtaaaacg
     2821 cctgagcgat cgcctcggta tcactgtgca acaggccgcc catgcatggg tcgatgcata
     2881 ctgtcagcaa gtgctaaagc cgctgtttac ggctgaagcg gattacggcc tggtgctgct
     2941 ggcgcatcag caaaatattc ttgtccagat gcttggggat ctgccggtcg gatttattta
     3001 ccgtgactgt cagggcagcg cttttatgcc tcacgcgaca gactggctcg attctattgg
     3061 cgaggcgcag gcggaaaata ttttcaccca tgagcagttg ctgcgctatt tcccttatta
     3121 cctgctggtt aactccactt ttgctgtgac cgctgcgctg ggggctgccg ggctggacag
     3181 cgaatcgaat ctgatggctc gtgtacgagc atcgctggct gaagtgcgtg atcaggtgac
     3241 tcataaaacc tgtctcaact acgtgctgga aagtccgtac tggaacgtaa aaggtaactt
     3301 tttctgttat ctgaacgatc ataacgagaa caccattgtt gacccttcgg tgatctattt
     3361 cgatttcgct aacccgctgc aggctcagga ggtctgaatg tctgaggcaa acattattca
     3421 cagcagatat ggactgcgct gtgaaaaact cgacaagccc ctgaatcttg gctggggact
     3481 ggacaatagc gcggtgttgc actgtcccgg ggagctgccg acagggtggc tgtgcgatgc
     3541 gctggatcag atatttatcg ccgctccaca actgtcagca gtggctctcc cctgggccga
     3601 atggcgtgag gagccacagg cgctgacgct ttttgggcag gtaaaaagcg acattatcca
     3661 tcgtactgcc ttctggcagt taccgttatg gttgagttca ccggcaaacc gggcctccgg
     3721 tgaaatggtt tttgatgcag agcgtgagat ttatttcccg cagcgcccac cccgtccaca
     3781 gggtgaggtt taccgccgtt acgatccacg tattcgcagg atgctgagtt tccgcattgc
     3841 cgatcccgtt tctgatgcag aacgtttcac ccgctggatg aatgatccgc gcgttgagta
     3901 tttctgggag caaagtggct cactggaggt acagaccgcc tatctggagc gccagctcac
     3961 cggtaaacat gcattcccgc tgattgggtg cttcgacgat cggccattca gctatttcga
     4021 aatctactgg gcggcggaag accgcattgg tcgtcactat tcgtggcagc cctttgaccg
     4081 tggcctgcat ctgctggttg gtgaacagca atggcgcggg gcccactatg tgcaaagctg
     4141 gctgcgcggg ctgacacatt acctgctgct ggatgagccc cgtacgcagc gcacagtact
     4201 ggagccacgc accgataacc tgcgcctgtt ccgccatctt gagcctgcgg gataccggac
     4261 aattaaagag ttcgacttcc cacataagcg ctcgcgcatg gtgatggcgg atcgtcatca
     4321 cttcttcacg gaggtcggtc tgtaatgaat cacaaggact gggattttgt taaccgtcgg
     4381 ctggtggcaa aaatgttgtc tgagatggag tatgagcagg ttttccacgc ggaatctcag
     4441 ggcgatgacc actactgcat taacctgccg ggagcacaat ggcgcttcat cgctgaacgt
     4501 ggtatctggg gctggctgtg gattgatgcc caaacgttgc gctgcacgga cgaaccagta
     4561 ctggcgcaga cgctgctgat gcagctaaag ccggtgctgt caatgagtga tgccactgtt
     4621 gcagagcata tgcaggattt gtatgccacg ctactgggcg acctgcaact gctgaaggcc
     4681 cgtcgcggac tgagtgccag tgacctgatt aatcttgatg ccgatcgtct gcaatgcctg
     4741 ctgagcggtc atcctaaatt cgtttttaat aaaggtcgcc gtggctgggg caaagaggcg
     4801 ctggaacgat atgcgccaga gtataccaac accttcagac tgcactggct ggcggtaaaa
     4861 cgtgaacata tgatctggcg ctgcgataac gatctggata ttcagcagtt gttgactgcc
     4921 gcaatggatc cgcaggagtt tacacgcttc agtcaggtct ggcaggaaaa cggactggat
     4981 cacaactggc tgccgctgcc ggtacatccg tggcagtggc agcaaaaaat cgctaccgac
     5041 ttcatcgctg attttgccga aggcaggatg gtgtctctcg gcgagtttgg cgaccagtgg
     5101 ctcgcccagc agtcgctgcg taccctgacc aacgccagtc gccggggcgg gctggatatc
     5161 aagctgccgc tgaccatcta caacacctca tgctaccggg ggatccctgg cagatacatc
     5221 gctgccggac cactggcttc acgctggcta caacaggttt ttgcgaccga cgccaccctg
     5281 gtgcaaagcg gcgcagtgat acttggtgaa ccggctgcag gctatgtctc ccatgaaggc
     5341 tatgccgcgc ttgcccgggc tccctatcgc taccaggaaa tgcttggtgt tatctggcgg
     5401 gagaatccgt gccgctggct gaaaccggat gaaagtccgg ttctgatggc aacactgatg
     5461 gagtgcgacg aaaacaatca gccgctggca ggcgcatata tagaccgctc cgggctggac
     5521 gctgaaacct ggcttacgca actgttccgg gtggtcgtgg ttcctctgta tcacctgctt
     5581 tgccgctacg gtgtcgcgct tattgcacat ggacaaaata taactctcgc catgaaagag
     5641 ggggttccac agcgtgttct gctgaaagac ttccagggcg atatgcgact ggtgaaagaa
     5701 gagttccccg aaatggactc tttgcctcag gaggttcgtg atgttacatc ccgcctgagt
     5761 gcggactact taatccatga tttgcagacg ggtcacttcg tgacagtact gcgttttatt
     5821 tcgccactga tggttcgtct tggcgtacct gaaaggcgat tttatcaact gctggcagca
     5881 gtgttgagtg attacatgaa aaaacatcca caaatgtcag agcgttttgc gcttttctca
     5941 cttttcaggc cacaaatcat tcgcgtggtg ctgaacccgg taaaactgac ctggcctgat
     6001 ctggatggcg gcagccgcat gctgccgaat taccttgagg atctgcaaaa tccgctgtgg
     6061 ctggtaactc aggaatatga atcatgaaaa aaagtgtcga ttttattggt gtagggacag
     6121 ggccatttaa tctcagcatt gctgcgttgt cacatcagat cgaagaactg gactgtctct
     6181 tctttgatga acatcctcat ttttcctggc atccgggtat gctggtaccg gattgtcata
     6241 tgcagaccgt ctttctgaaa gatctggtca gtgctgttgc acctacaaat ccctacagtt
     6301 ttgttaacta tctggtgaag cacaaaaagt tctatcgctt ccttacaagc agactacgta
     6361 cagtatcccg tgaagagttt tctgactacc tccgctgggc tgctgaagat atgaataacc
     6421 tgtatttcag tcataccgtt gaaaacattg atttcgataa aaaacgtcga ttgtttctgg
     6481 tgcaaaccag ccagggagaa tattttgccc gcaatatctg ccttggtaca ggaaaacaac
     6541 cttatttacc accctgtgtg aagcatatga cacaatcctg tttccatgcc agtgaaatga
     6601 atcttcgtcg gccggacctt agtggaaaac ggataaccgt ggttggtgga ggacagagtg
     6661 gtgcagacct gttccttaat gcattacgcg gggaatgggg agaagcggcg gaaataaact
     6721 gggtctcccg gcgtaataat tttaacgcac tggatgaggc tgcttttgct gatgagtatt
     6781 ttacacctga atatatttca ggcttctccg gactggagga agatattcgc catcagttac
     6841 tggatgagca gaaaatgaca tcggatggca tcactgccga ttctttactg accatttatc
     6901 gtgagttgta ccaccgtttt gaagttctga gaaaaccaag aaatatccgt ctgctaccca
     6961 gccgctcggt aacaactctg gaaagtagtg gtcctggctg gaagttgctg atggagcatc
     7021 atctggatca gggcagggag agcctggaaa gtgatgtggt gattttcgcc acaggttacc
     7081 gttctgcgtt gccacaaata cttccctcac tgatgcccct gatcaccatg cacgataaga
     7141 acacctttaa agtgcgtgat gacttcactc tggaatggag tggcccgaaa gagaacaaca
     7201 tcttcgtggt caacgccagt atgcaaaccc atggcatcgc cgaaccccag ctcagcctga
     7261 tggcatggag atctgcacgt attcttaatc gcgtaatggg acgtgattta ttcgatctca
     7321 gtatgccgcc cgccctgatt cagtggcgca gcggcaccta gggaaaacgc agccggaggc
     7381 tgcttcttta actcgctaca cagcatcttt gggctgattt tttccgcccg tatggaggaa
     7441 taatgatgat aagcaaaaag tatacgcttt gggctctcaa cccactgctt cttaccatga
     7501 tggcgccagc agtcgctcaa caaaccgatg atgaaacgtt cgtggtgtct gccaaccgca
     7561 gcaatcgcac cgtagcggag atggcgcaaa ccacctgggt tatcgaaaac gccgaactgg
     7621 aacagcagat tcagggcggc aaagagctta aagacgcact ggctcagctg atccctggcc
     7681 ttgacgtcag cagccggagc cgcaccaact acggtatgaa tgtgcgtggc cgcccgctgg
     7741 tcgtgctggt tgacggcgtg cgtctcaact cttcacgtac cgacagccga caactggact
     7801 ctatagatcc ttttaatatc gaccatattg aagtgatctc cggtgcgacg tccctgtacg
     7861 gcggcggcag taccggtggc ctgatcaaca tcgtgaccaa aaaaggccag ccggaaacca
     7921 tgatggagtt tgaggctggc accaaaagtg gctttagcag cagtaaagat cacgatgaac
     7981 gcattgccgg agctgtctcc ggcggaaatg agcatatctc cggacgtctt tccgtggcat
     8041 atcagaaatt tggcggctgg tttgacggta acggcgatgc caccttgctt gataacaccc
     8101 agaccggcct gcagtactcc gatcggctgg acatcatggg aaccggtacg ctgaacatcg
     8161 atgaatcccg gcagcttcag ttgatcacac agtactataa aagccagggc gacgacgatt
     8221 acgggcttaa tctcgggaaa ggcttctctg ccatcagagg gaccagcacg ccattcgtca
     8281 gtaacgggct gaattccgac cgtattcccg gcactgagcg gcatttgatc agcctgcagt
     8341 actctgacag cgcttttctg ggacaggagc tggtcggtca ggtttactac cgcgatgagt
     8401 cgttgcgatt ctacccgttc ccgacggtaa atgcgaacaa acaggtgacg gctttctctt
     8461 cgtcacagca ggacaccgac cagtacggca tgaaactgac tctgaacagc aaaccgatgg
     8521 acggctggca aatcacctgg gggctggatg ctgatcatga gcgctttacc tccaaccaga
     8581 tgttcttcga cctggctcag gcaagcgctt ccggagggct gaacaacaag aagatttaca
     8641 ccaccgggcg ctatccgtcg tatgacatca ccaacctggc ggccttcctg caatcagact
     8701 atgacatcaa taatctcttt accctcaacg gtggcgtacg ctatcagtac actgaaaaca
     8761 agattgatga tttcatcggc tacgcgcagc aacggcagat tgccgccggg aaggctacat
     8821 ccgccgacgc cattcctggc ggctcagtcg attacgacaa cttcctgttc aacgccggtc
     8881 tgctgatgca catcaccgaa cgccagcagg catggctcaa cttctcccag ggcgtggagc
     8941 tgccggaccc gggtaaatac tatggtcgcg gcatctatgg tgctgcagtg aacggccatc
     9001 ttcctctaac aaagagtgtg aacgtcagcg acagcaagct ggaaggcgtg aaagtcgatt
     9061 cttatgagct gggctggcgc tttactggca ataatctgcg cacccaaatc gcggcctact
     9121 attcgatttc tgataagagc gtggtggcga ataaagatct gaccatcagc gtggtggacg
     9181 acaaacgccg tatttacggc gtggaaggtg cggtggacta cctgattcct gatactgact
     9241 ggagtaccgg agtgaacttc aacgtgctga aaactgagtc gaaagtgaac ggtacctggc
     9301 agaaatacga tgtgaagaca gcaagcccat caaaagcgac agcctacatt ggctgggcac
     9361 cggacccgtg gagtctgcgc gtgcagagca ccacctcctt tgacgtgagc gacgcgcagg
     9421 gctacaaggt cgatggctat accaccgtgg atctgctcgg cagttatcag cttccggtgg
     9481 gtacactcag cttcagcatt gaaaacctct tcgaccgtga ctacaccact gtctgggggc
     9541 agcgtgcacc actgtactac agcccgggtt acggcccagc gtcactgtac gactacaaag
     9601 gcaggggccg aacctttggt ctgaactact ctgtgctgtt ctgacgggga tgcttttgca
     9661 acaagggtat gctgtaaaca acatggtcct tggtggccat gttgtttaca gccagtataa
     9721 tatacagcct taacaagata ttccgtctcc ggaatggact gttcaccact gaataacatt
     9781 atgtctgttt tatggatctt tgactgaaat ttatcgcata tcctcatttc attgtccgtc
     9841 tgaaaactaa ccttacaagt aagcgtcgtc tcagcaccgt ctggcagatc ctgaaattcc
     9901 tgggaggatg atctgcgccc aatatcctga gccggaactt tgctgcaatg aaggccaacg
     9961 aaaaatgggg gagtatgtta tagagtactt gctacagggt aaaaagaggt acctgtcgct
    10021 ggttctccgt tcagtttaac cgggagattt tctcctgcgc ctgtcataaa gtccggtaat
    10081 ggagattgtt aatacgatgg tgcacgatgc attgtcagtg cccggcccgg aggatgcccc
    10141 gtagctacat acggatcagg gttggcaata tcgaatggca ggctataggc aaagttaaag
    10201 ccccatggag tagcacaaaa tatgccgcac aaaggaaacg gtctgaataa cgcagcgatg
    10261 gagaacttct tcggcacact gcaaaatcgc atcgtggtcg atcgctaatt cgtcgtgaat
    10321 cactgaacga tgttccatgc gaacagatat tcgatcatat cgaaatatta aacattaccc
    10381 ctccccacat tgggcaaaaa aaaacaaaaa acgatcaatt aacgatcaat tagtattgat
    10441 tcacataatc tctcatcatt aatgagaaca ttgtcacata tttacaatat agaactgtta
    10501 cttttagcaa gctgttagta accaaccgtt actaataatt ttaattctta atactttgtt
    10561 cattcaataa atgagttgag agaatatatg aataaaatat actcccttaa atatagtgct
    10621 gccactggcg gactcattgc tgtttctgaa ttagcgaaaa gagtttctgg taaaacaaac
    10681 cgaaaacttg tagcaacaat gttgtctctg gctgttgccg gtacagtaaa tgcagcaaat
    10741 attgatatat caaatgtatg ggcgagagac tatcttgatc ttgcacaaaa taaaggtatt
    10801 ttccagcccg gagcaacaga cgtaacaatc actttaaaaa acggagataa attctctttc
    10861 cataatctct caattccgga tttttctggt gcagcagcga gtggcgcagc taccgcaata
    10921 ggaggttctt atagtgttac tgttgcacat aacaaaaaga accctcaggc cgcagaaact
    10981 caggtttacg ctcagtcttc ttacaaggtt gttgacagaa gaaattccaa tgattttgag
    11041 attcagaggt taaataaatt tgttgtggaa acagtaggtg ccaccccggc agagaccaac
    11101 cctacaacat attctgatgc attagaacgc tacggtatag tcacttctga cggttcaaaa
    11161 aaaatcatag gttttcgtgc tggctctgga ggaacatcat ttattaatgg tgaatccaaa
    11221 atctcaacaa attcagcata tagccatgat ctgttaagtg ctagtctatt tgaggtcacc
    11281 caatgggact catacggcat gatgatttat aaaaatgata aaacatttcg taatcttgaa
    11341 atattcggag acagcggctc tggagcatac ttatatgata acaaactaga aaaatgggta
    11401 ttagtcggaa caacccatgg tattgccagc gttaatggtg accaactgac atggataaca
    11461 aaatacaatg ataaactggt tagtgagtta aaagatacct atagtcataa aataaatctg
    11521 aatggcaata atgtaaccat aaaaaacaca gatataacat tacaccaaaa caatgcagat
    11581 accactggta ctcaagaaaa aataactaaa gacaaagata ttgtgttcac aaatggggga
    11641 aatgtcctgt ttaaggataa tttggatttt ggtagcggtg gtattatctt tgacgaaggc
    11701 catgaatata acataaacgg tcagggattt acatttaaag gagcaggaat tgatatcgga
    11761 aaagaaagca ttgtaaactg gaatgcattg tattccagtg atgatgtttt acacaaaata
    11821 ggccccggta ctctgaatgt tcaaaaaaaa cagggggcaa atataaagat aggtgaagga
    11881 aatgttattc ttaatgaaga aggaacattt aacaatatat accttgcaag cggaaatggt
    11941 aaggtaatac taaataaaga taattccctt ggcaatgatc aatatgcggg gatatttttt
    12001 actaaacgtg gtggcacgct agatttaaat ggacacaatc agacttttac tagaattgcc
    12061 gccactgacg atggaacaac aataactaac tcagatacaa cgaaagaagc cgttctggca
    12121 atcaataacg aagactccta catatatcat gggaacataa atggcaatat aaaactaacg
    12181 cacaatatta attctcagga taagaaaact aatgcaaaat taattctgga tggtagtgtc
    12241 aacacaaaaa atgatgttga agtcagtaat gccagtctta ccatgcaagg ccatgcaaca
    12301 gagcatgcaa tattcagaag cacagcgaat cattgctccc tggtatttct ttgtggaacg
    12361 gactgggtca ccgttttgaa agaaacagag agttcatata ataaaaagtt caattctgat
    12421 cacaaaagta ataatcagca gacctcattt gatcagccag actggaaaac cggggtgttt
    12481 aaatttgata cattacacct gaacaatgct gacttttcaa tatcacgcaa tgccaatgtt
    12541 gaaggaaata tatcagcaaa taaatcagct atcacaatcg gcgataaaaa tgcttacatt
    12601 gataatcttg cagggaaaaa tattactaat aatggttttg acttcaaaca aactatcagt
    12661 actaatctat ccataggaga aactaaattt acaggtggca tcactgcaca taacagccaa
    12721 atagccatag gtgatcaagc tgtagttaca cttaatggtg caacctttct gaataatact
    12781 cctataagta tagataaagg agcaaaagtt atagcacaaa attccatgtt cacaacaaaa
    12841 ggtattgata tctccggtga gctgactatg atgggaatcc ctgaacagaa tagtaaaact
    12901 gtaacgccgg gtctccacta cgctgctgat ggattcaggc tgagtggtgg aaatgcaaat
    12961 ttcattgcca gaaatatggc atctgtcacc ggaaatattt atgctgatga tgcagcaacc
    13021 attactctgg gacagcctga aactgaaaca ccgactatat cgtctgctta tcaggcatgg
    13081 gcagagactc ttttgtatgg ctttgatacc gcctatcgag gcgcaataac agcccccaaa
    13141 gctacagtta gcatgaataa tgcgatctgg catctaaata gccagtcatc aattaatcgt
    13201 ctagaaacaa aagacagtat ggtgcgtttt actggtgata atgggaagtt tacaaccctt
    13261 acagtggaca accttactat agatgacagt gcatttgtgc tgcgtgcaaa tctggcccaa
    13321 gcagatcagc ttgttgtcaa taaatcgttg tctggtaaaa acaaccttct gttagtcgac
    13381 ttcattgaga aaaatggaaa cagcaacgga ctgaatatcg atctggtcag cgcaccaaaa
    13441 ggaactgcag tagatgtctt taaagctacg actcggagta ttggcttcag tgatgtaaca
    13501 ccggttatcg agcaaaagaa cgatacagac aaagcaacat ggactctgat cggctataaa
    13561 tctgtggcca acgccgatgc ggctaaaaag gcaacattac tgatgtcagg cggctataaa
    13621 gccttccttg ctgaggtcaa caaccttaac aaacgtatgg gtgatctgcg tgacattaac
    13681 ggtgagtccg gtgcatgggc ccgaatcatg agcggaaccg ggtctgccgg cggtggattc
    13741 agtgacaact acacccacgt tcaggtcggt gcggataaca aacatgaact cgatggcctt
    13801 gacctcttca ccggggtgac catgacctat accgacagcc atgcaggcag tgatgccttc
    13861 agtggtgaaa cgaagtctgt gggtgccggt ctctatgcct ctgccatgtt tgagtccgga
    13921 gcatatatcg acctcatcgg taagtacgtt caccatgaca acgagtatac cgcaactttc
    13981 gccggccttg gcaccagaga ctacagctcc cactcctggt atgccggtgc ggaagtcggt
    14041 taccgttacc atgtaactga ctctgcatgg attgagccgc aggcggaact tgtttacggt
    14101 gctgtatccg ggaaacagtt ctcctggaag gaccagggaa tgaacctcac catgaaggat
    14161 aaggacttta atccgctgat tgggcgtacc ggtgttgatg tgggtaaatc cttctcgggt
    14221 aaggactgga aagtcacagc ccgcgccggc cttggctacc agtttgacct gtttgccaac
    14281 ggtgaaaccg tactgcgtga tgcgtccggt gagaaacgta tcaaaggtga aaaagacggt
    14341 cgtatgctca tgaatgttgg tctcaacgct gaaattcgcg ataatcttcg cttcggtctt
    14401 gagtttgaga aatcggcatt tggtaaatac aacgtggata acgcgatcaa cgccaacttc
    14461 cgttactctt tctgataaca gcccgggccg cgtttgcggc ccttcttcta ccggagagaa
    14521 tatgtattac cctgtgacag actatatcgc tcttgctctc attattagct ttctttttct
    14581 gacattattt atctgcctgt tatgccttaa acatgagcga ataaaaaaag aaactatcag
    14641 gcaaaaaaat gcacatattc tggatcatgg ctggaatgca actgaggtag cctgagttta
    14701 acggacactc cttcctgaaa tagaatggca tcagaa
//
LOCUS       DAPOXO010000107        14634 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPOXO010000107 DAPOXO010000000
VERSION     DAPOXO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14634
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.107"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(71..1435)
                     /gene="tdcG"
                     /locus_tag="ROH59_004289"
     CDS             complement(71..1435)
                     /gene="tdcG"
                     /locus_tag="ROH59_004289"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDX4806697.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEELLSKTYYSVGGGFIVEEEHFGLS
                     HDVETPVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(1507..1896)
                     /locus_tag="ROH59_004290"
     CDS             complement(1507..1896)
                     /locus_tag="ROH59_004290"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HDX4806698.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            complement(1910..4204)
                     /gene="tdcE"
                     /locus_tag="ROH59_004291"
     CDS             complement(1910..4204)
                     /gene="tdcE"
                     /locus_tag="ROH59_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HDX4806699.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPLDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIRSSFHAYGREMDSEFEYIFTDLRKTHNQGVFDTYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRRALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEALPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGMDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            complement(4238..5446)
                     /gene="tdcD"
                     /locus_tag="ROH59_004292"
     CDS             complement(4238..5446)
                     /gene="tdcD"
                     /locus_tag="ROH59_004292"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312022.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HDX4806700.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGVEIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHL
                     GKVNAPAEFA"
     gene            complement(5472..6803)
                     /gene="tdcC"
                     /locus_tag="ROH59_004293"
     CDS             complement(5472..6803)
                     /gene="tdcC"
                     /locus_tag="ROH59_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HDX4806701.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            complement(6825..7814)
                     /gene="tdcB"
                     /locus_tag="ROH59_004294"
     CDS             complement(6825..7814)
                     /gene="tdcB"
                     /locus_tag="ROH59_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HDX4806702.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
     gene            complement(7913..8851)
                     /gene="tdcA"
                     /locus_tag="ROH59_004295"
     CDS             complement(7913..8851)
                     /gene="tdcA"
                     /locus_tag="ROH59_004295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HDX4806703.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTATLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVD"
     gene            9166..9384
                     /gene="tdcR"
                     /locus_tag="ROH59_004296"
                     /pseudo
     CDS             9166..9384
                     /gene="tdcR"
                     /locus_tag="ROH59_004296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417589.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TdcR"
     gene            complement(9950..10326)
                     /gene="rnpB"
                     /locus_tag="ROH59_004297"
     ncRNA           complement(9950..10326)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ROH59_004297"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(10359..11504)
                     /gene="garK"
                     /locus_tag="ROH59_004298"
     CDS             complement(10359..11504)
                     /gene="garK"
                     /locus_tag="ROH59_004298"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417593.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HDX4806704.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGAERHARVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDSGASRIFGPQKGASEAM
                     IVELDNNLSHYADVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTNDVGVVH
                     QHGIDAVFSVLTSIGTLDEALRGAYDNICRASRNIAATLAIGMRNAG"
     gene            complement(11601..12491)
                     /gene="garR"
                     /locus_tag="ROH59_004299"
     CDS             complement(11601..12491)
                     /gene="garR"
                     /locus_tag="ROH59_004299"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDX4806705.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETAATAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            complement(12521..13291)
                     /gene="garL"
                     /locus_tag="ROH59_004300"
     CDS             complement(12521..13291)
                     /gene="garL"
                     /locus_tag="ROH59_004300"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HDX4806706.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            complement(13307..14605)
                     /gene="garP"
                     /locus_tag="ROH59_004301"
     CDS             complement(13307..14605)
                     /gene="garP"
                     /locus_tag="ROH59_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GarP"
                     /protein_id="HDX4806707.1"
                     /translation="MHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMG
                     YIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGIS
                     MFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLT
                     FAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKP
                     GSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKV
                     GLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNN
                     TTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGY
                     LVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
BASE COUNT         3801 a         3870 c         3382 g         3581 t
ORIGIN      
        1 tatttgcggc agatcacaat aaaaaagggt gcacattttg tgcacccaag gatgatagct
       61 gacagcaatg tcagccgcag accactttaa tagccagtcc tccgcgtgat gtttcgcggt
      121 atttatcgtt catatctttg ccggtttcat acatcgtctc gatcacttta tcgagtgaaa
      181 cacgcggtgc cgaggtgcgg cgcatcgcca tccgcgcggc gtttactgct ttcacggcat
      241 taatggcatt acgttcaatg cacgggattt gtacctgtcc ggcaaccgga tcgcaggtca
      301 gcccaaggtt atgctccatc gcgatttccg ccgcattgca tacctgcgcc ggactgccac
      361 ccagtagttc agttaaccct gccgctgcca ttgaacaggc cacgccaatc tccccctgac
      421 agccgacttc cgcgccagag atggaggcgt tcattttata cagcgcgcca attgcccccg
      481 ctgccagaaa atagcgggca attgaccgct cgtttaccgg acgacggaac ttatcgtaat
      541 aagccagcac tgccggaata atgccgcacg caccgttagt cggtgccgtt accacgcgcc
      601 cgccagctgc gttttcttca ctaaccgcca gcgcgtacat gttgatccag tcgatgacat
      661 tcatcggatc gttagagatg ttatcgctgg aaaccagttg acgacgcagc gctacggcac
      721 ggcgcggcac attgagcgga ccaggcagca cgccttcagt attcattcca cgttcaatac
      781 cgtcatgcat cacttgccag atacgggcaa accctgcgtc aatttccgct ttactgcgca
      841 gcgccagctc gttgtgcatc atcaggccag atatagacag gccgttgtaa tcacacattt
      901 tcagcagttc acctgctgag tggaaatcgt aaggtacggg tgtttcgaca tcgtgcgaca
      961 ggccgaagtg ttcttcttcg acaataaacc cgccgccgac agagtaatag gttttgctta
     1021 atagctcttc ctgtcccttc caggcagtga tccgcattcc gttctcatgg cgaggcaaca
     1081 tttcgggatg gaagataatg ttctttgcta caggaaaatc aacaatatgc gcgccagaag
     1141 ccaccggcaa ccgcccgctg cgcgtcacta actctataaa tgcagggatc tcatcaatga
     1201 caacatcctg cggactgttt cctgccagtc ccatgatgat ggcgacatcc gtggcatggc
     1261 ctttgcccgt cagtgacaac gacccgtaca gatcgaccac aatatggctc gtcgcggtta
     1321 ataagccgct actttccagc cgatcaataa aactttttcc ggcattcatt ggccccacag
     1381 tatgcgaact ggagggacca atcccaattt tgaaaatatc gaatgcacta atcatatcca
     1441 caccctcgga ttgccgttca gtgaagtgga gcggaacgac cttgcgaccg tcccgctcac
     1501 gaggctttac gcactacgta ctgcgatggc ttcaatttcc agcttcacat ctttcggcaa
     1561 acgcgcgacc tgcacacagc tccgggtcgg gtaggtcgcc tgatgttcat cgaagaactg
     1621 cttatagact tcattgatgg tggcaaaatc attcagatcg gtgatgaaca cggtcatctt
     1681 gatgatatcg cccacactca gcccggcagc aaccacgatc gctttgacgt tttcgaggct
     1741 taaacgcgcc tgatcttgca catcagccgg gatctcaccg gtctgtgggc aaaccggaat
     1801 ttgcccggag gtgaagacca tgctgcctaa atcaacgccc tgaacataag ggccgattgc
     1861 gcctggggca cgttgcgttt cgataatctt tttcatacat cctccggcgt cagagcgcct
     1921 gggtaaaggt acgtgaaata acatcctgtt gctgttcacg ggtcagtgcg ttgaagcgca
     1981 cggcgtagcc agagacacgg attgtcaggt taggatattt ttccgggtgc tcgatggcat
     2041 ccagcagcat ttcccgattc attacgttga cgttgaggtg ttgaccgcct tcgacatccg
     2101 cttcgtggtg gaaataccca tccagcaggc cgacaaggtt ggttttacgt actggatctt
     2161 ctttgcccag cgccgcaggg acgatggaga aggtgtacga gatcccatct ttggcgtagg
     2221 tgaacggcag tttcgccacc gacgtcaatg aggccacggc acctttgcga tcacgaccgt
     2281 gcatcgggtt agcgcccggc gcgaacggtg ttccggcgcg gcgaccgtcc ggcgtgttcc
     2341 cggttttctg accgtacacc acgttagagg tgatagtcag aatcgattgg gtcggcacag
     2401 cattgcgata ggttggcaaa gctttaattt tcttcataaa gcgttcaacc agatcgcagg
     2461 caatgctgtc tacgcgctcg tcgttgttgc catactgcgg atattcgccg tcaatctcga
     2521 aatccaccgc caggccgttt tcatcacgga ttggtttcac acgagcatat ttgatggcag
     2581 acagggagtc cgttgccacc gacaggcccg cgatgccgca cgccatggtg cgatagacat
     2641 cacgatcatg tagcgccatc agcgaagctt cgtagctgta cttgtcgtgc atgtagtgaa
     2701 tgatattcag cgcgctgatg tactgtaccg ccagccagtc catgaagtgg tcgaggctat
     2761 ccatcacttt gtcgtagtcc agcacgtcat ccatcaacgg agccgttttc gggccaacct
     2821 gaatcttcag cttctcgtcc attccgccgt tgattgcgta cagtagcgtt ttcgccaggt
     2881 tagcgcgcgc accgaagaac tgcatctgct taccaatcac cattgggctg acgcaacagg
     2941 caatcgcgta atcgtcgcta ttgaagtcag tacgcatcag atcgtcgttt tcatactgca
     3001 aagaggatgt gacgatagac acctgcgcgg catatttttt gaaggcaatc ggcaaggctt
     3061 ccgaccacag aatagtcagg ttaggttccg gtgcaggccc catagtgtgc agggtgtgta
     3121 aatagcggaa ggagtttttg gtcaccaggg ttcgaccgtc caaccccatc ccgccgatca
     3181 cttccgtcgc ccagatcggg tcgccggaga acagcgaatc aaattccggc gtacgcaaga
     3241 agcgcaccat acggatcttc atgatgaagt ggtcgatcag ttcctgtgcc tgctgctcat
     3301 tgagtacgcc tgctttaaag tcgcgctcaa tgtagatatc gaggaacgat gccgtgcgcc
     3361 ccagcgacat cgcgccgcca ttttgcgatt tcactgccgc caggtaagcg aagtagagcc
     3421 actgcacggc ttcttgtgca ttctgcgctg gacgagagat atcaaagcca tatttcgccg
     3481 ccatttcctg aatctgtaac agcgcacggc gatgttctgc cagttcctca cgcagacgaa
     3541 tggtggcttc gagatcttcg cctttttcca gacgggactg gagatcggca aactgcagtt
     3601 cgcgttcacg taccagataa ctgatgccgt acagtgccac acggcgatag tcaccgatga
     3661 tacgcccacg accataacca tctggtaaac cggtcagtac accagattta cggcagcgca
     3721 gcatatccgg tgagtaagta tcaaatacgc cctgattatg ggttttacgc agatcggtaa
     3781 agatgtattc aaattcgcta tccatttcac gaccatacgc gtggaatgaa cttctaatca
     3841 tattaatgcc gccgaacgga tgcagcgcac gctttaatgg cgcatccgtt tgcagaccca
     3901 ctattttttc cagcggctgg ttaatatatc ccgcgtcatg agcggtaatt gtggtggcaa
     3961 tattggtatc gaaatccaat ggcgcgtgag tcgcattttc gatacggatg ccttccatga
     4021 ctttttccca caattccgtg gtggcaggcg tcgcttcggc gagaaaagat tcatcgcctt
     4081 cataaggtgt atagttatgt tgaataaaat cgcggacatt aatttcgttt ttccagtccg
     4141 tacctttaaa gccaagccat gcgtcggcgt acagcttatc gctggtatca atatctacct
     4201 tcatgaaaaa taatctctct acaatacttc aactaaatta tgcaaattct gcgggcgcgt
     4261 tcactttgcc taaatgaatg gcatccaaag caatcatttt ttcttcgtta gtcggaatta
     4321 cggcgcaaat gacacgcgca ttttcactgg aaacaattcg ctctccaaaa gagttagagc
     4381 gattattcat ttctgtatca atttctacgc ctaatacagc taaatgttcc atgaccagac
     4441 gacgaattaa acttgaattc tctcctattc cgccggtgaa tataattcca tccaggcgat
     4501 gtaatgaagc agcgtgtccg gcaatatgac gggcaattcg gtgaacaaag gttttaattg
     4561 ccagttgcgc gcgttcgtga ccttcatgcc aggctttttc cagaacacgt aaatccgaag
     4621 aaaggccgga aatacctaat aatcccgact ctttattcac tacgcgttcc aggtccccca
     4681 ggctctggtt ggtttggctg gcgacccagg acatcgcccc gaagtcgaca tcaccactgc
     4741 gggtacccat catcaagcct tccagcggcg tcattcccat tgaagtgtca acactctgac
     4801 cgttgcgaac cgcgcagatt gatgcgccat tgccaagatg cgccacaacc aggccggagt
     4861 catcttccgc cagattcagc agcgaatgtg cgcgctggga aacatagcgg tgcgacgtgc
     4921 cgtggaaacc ataacggcgt acacctaact cttcataata tttccacggc aggccgtata
     4981 aataagcttc cggagccatc gtctggtgga aactggtatc aaataccgcc acctgagtta
     5041 cgcccgggaa taattgctgc gccgattcaa taccacttaa attggcgtaa ttatgcaggg
     5101 gtgccagtgg agaaacgcga cggatattat caatgacttc atcggtaata atggcggact
     5161 cggtaaaaat actgccgccg tgagcgatgc ggtggccaat taaagccaca ctgtcattta
     5221 aattccgttt ttccagttca aatgcaattg ccttcaatgc accttcgtag ctgtggtgag
     5281 ccagcggtgc tggctctccc ccatttacgg ataagaatgc attttccgag ttaataccgt
     5341 cggcaatacc tgacattaat acttcacagt cgctggcatt gagtacggaa aacttaatcg
     5401 aagacgaacc acagttaata accaaaacaa ccggaaattc attcatctct tttctcatcc
     5461 tgagttacgg attaaaacag tttgtatacg atgttcagga tggtcagcag accaatcacg
     5521 gtaacaaaca cgttatccag acgaccacgg tatttcgcca gagacggcgc tttacggatg
     5581 gcatacatcg gcaacaggca cagcagtgat gcgataatcg gtgcgcccat ggcttcaatc
     5641 aagtcgagga tgttcgggtt ggcgtaggca acaacccagg tggagcccat aatgaaaatc
     5701 atgctgatag tattcagttt acccagcgac actttggttt tgtcaccttt ataaccgaac
     5761 ttcagaatca aaccattcag cccttccagc gtccccagat agtgaccgaa gaaagatttg
     5821 aaaatagcca cgagtgcgat gatggaagcg gcatattcca gtgtaatcgc aaacgttgtt
     5881 ttggtaccgg tcatggacgc aaagtggtta gccagataag aaagcactgg aatattctgc
     5941 gctttcgctt cagccatatt cgccggagac agcgtaaaca ggcagctaaa ggcaaagaac
     6001 atcaccactg caaccatcag catactggcg cgagagatga tttgtgaaca tttacgctcg
     6061 gtgaagtcgc gaccaaaatc tttctcgtac tcttcacgtt tagaaaccac gaaggaagag
     6121 acgattggcg agaagttaaa ggagaaaacc atgatggaaa tccccagcca gacggtgatc
     6181 aggataccgt catgaccagt taacgacagc gaaccgaggt caacctggtc gataactgca
     6241 gagttccagt aagggatcag cgaaagagaa atcagcacca ggctggcgat aaacggccat
     6301 accagatagc tcatcacttt aaccatcaga tccttaccaa accagatgac gaaagccatc
     6361 agcagcaaca ggaacagcgc cacaaagccg cgattcagcg gtgcaaagcc gagctggttt
     6421 tcccagaacg tcataaaggt gttggtaatg gtaacgccat aaatccacaa cagtgggcaa
     6481 atcgcgaaga agtacaggaa cgtgataacc acgccgccag ttttaccaaa atgctcttcc
     6541 accgtttccg taatgttgcc ggaagggtta gagccagaaa gacacagacg cgccagtgcc
     6601 cggtggcaat aaaacgcgat ggggtatgct aataccaaca tcagaagaat cgggatcagt
     6661 ccgccaaaac ctgcgcggat agggaagaac agcaccccgg cgccgattgc cgtaccaaac
     6721 aagcctaacg tccatgtggt atctgattta cgccaggacg attgttttgt ctggctggat
     6781 acaatgctat ctgaagtact catatcctat cctcaacgaa ttaattaagc gtcaacgaaa
     6841 ccggtgattt gagagacgcg agaaagatcg atattgccgc cggaaataat actgacggtt
     6901 tttctgtttt gaatatattg gtctaattta ccgcttaata atgcagcaca tgccagagcg
     6961 cctgcgcctt cggtgacgac tttattgcgc tgaattaagg caatcatact gtttctgatt
     7021 tcgtcttcgc tgaccagcac gatgtcatcg actaattcac gaacgatttc gtaagttaaa
     7081 ttacccgggc gggagacatc acaaccatcc gccagggtgc cggtagttcg gtgcgtagtt
     7141 atttctccgg agtggaaaga agccgccatg ccgtgaacgt tttcagactg tacgccaata
     7201 acacggatgg tcgggttgat agatttaatt gccaccgcaa taccagcaat taaaccgccg
     7261 ccgccaattg gcacaatcac gttatcgaca tcatagagat cttccataat ttccagacca
     7321 atcgttccct ggccagcaat cactttcgga tcatcgtaag gtgggataaa aatacggcct
     7381 tccatttcga caatttcgct cactttagca atagtgtcgt tgaagttatc accatgcaaa
     7441 acgacttctg cggagtagtc gcacgttgcc gcgactttgg atttcggcgc accttttggc
     7501 atcaccactt taccgtcaat acccagcatc gcgcaggaga gcgaaacccc ttgcgcatgg
     7561 ttgcccgcag agcaggccac tactccttta cgtttttccg catcagtcag tgaacttaat
     7621 ttattaaatg cgccacgaat tttaaatgaa ccagtacgct gcatgttttc gaatttgagg
     7681 aatatttcac ctttgcaacg ttcactaaaa tagttggagc gaggcatacc tgttttataa
     7741 attcgcccag ccagtcgttg ttttgcttca atgatgtcat caatagcaac cgggagatcg
     7801 tatgtaatat gcattataaa acctcttagc ctgaattaaa tatgtaggta accgtaaccg
     7861 acacctgcaa aacagacagg tggattattt atgtttaaat taaaacaaat aactaatcaa
     7921 cttcaattaa ttgccttcgt ctacacccat tataagatga atactctttg gctaattcca
     7981 ccaaaaccga tgctgctttt ttaatacgat aatttttcga ccataccgcg gcatattgtg
     8041 ccacaggtaa tgtttcttca accggaatag taataaattg attagaacca aaaggtgatg
     8101 tcatatcaca aggaattaca gttaagaaat cagcattgag aacaagatta taaattgtca
     8161 cgactgagtc ggttttaacg atgttttcaa tactgatgcc atttctttgt aacgtagtaa
     8221 gtagttcgct gtagtacccc atattggttt gtggcaacac ccactgttcg ttcttcaacg
     8281 actccagcgt ggcggtgccg gtgcatgttc gggacttact ggctaccagc acaaactcgg
     8341 actcgaacag cggctcaaca tgtaaatcct gaagcttcat ttctgcgctt aacgtaccaa
     8401 tcgcaaaatc cagtcgaccg tcgcggattg ccggtaagaa cgaagacagt tgcgcttcat
     8461 acatagaaac ctgcgctttc gggaacacct ctttgaactt gttgatcatc cctgacataa
     8521 aagtaaaacc aatcaatgaa ggaaaaccaa atgagacttc caccaccgcc tcagaagaca
     8581 taccgcttat ctcattaacc atatttttca tttcacgggt aatggattcg gaacgggaga
     8641 gtaacaattg accggcaggt gttaatgtta caccggtatt tttccgcacc actaactcca
     8701 ccccaaaata atcttcaata tcgttaatga ttttactgac ggccggttga gttaacccta
     8761 actcttttgc agccgagccg atagaaccac ttctaataac ttcctgaaag actaccaggt
     8821 gctgcgtttt cggaagaaga atagtgctca taacgaccta cgttaattac ctcattgacg
     8881 gtatgaagtg tatcaaaatg aaatgaacag gatatgtgcg accactcaca aattaacttt
     8941 caatactttc catagcatcg ttaccccaat taaatacctt taagtatcaa caagttaaag
     9001 tatgaaaatc agcataaacc ctgatttttg tcaaaaaaaa tgacggggat aaccatattt
     9061 tatggcgata acatcattct ttatgtggtt aatacaaaaa aggggctgag actatatttc
     9121 aagcaattac cggataatta ccaggcaaaa tttgagttaa atttaatgag taagttctca
     9181 aattttatta taaacaaacc attttcagcg ataaataatg cggcacgtca cattttttaa
     9241 cgctatttgt tggagaacaa acatttattt tatcaatatt ttaaaatttc gaatacaggt
     9301 attgatcatc tcgaacaatt gattaacgtc aacgttttct cttctgacag gatgtcattt
     9361 tgtgaatgca atcgttttcc ataaattctt ctcccatcat aggcaacgaa gagcattttg
     9421 tgttgaggat cacaaaacga ataattgctg gtcgccgcga taaggtcaga cgaagacaac
     9481 aagggggatt ctcactgtgc tttacatcag cgtaggccat agaatgttgc ttcgttgact
     9541 gtaatgccgg gtaaatgagc gttttttgat agtgcgaaag aaccgtgcaa ggagaataag
     9601 catctattat tgtttgtcat gatgacaagg caggcatcaa tgaaaggctt ctcaattgca
     9661 catattcttc acccttcaat cccgtcaatg cacgcagtgg ttaacaatca caatagaaat
     9721 attgattatt ggacggtaaa aatttaggtt ataacgccca aattattcaa cgatcggaca
     9781 atacctgcga acttacaatt aatgagagaa atatacgtat aattacgacc ttttaaatgc
     9841 aatatagact taataacttc ttacaaagtc tgttattaat accgtagata ttcatcttac
     9901 cctgggcaca caaagcaaaa acccgccgaa gcgggttttt acgtaaatca ggtgaaactg
     9961 accgataagc cgggttctgt cgtggacagt cattcatcta ggccagcaat cgctcactgg
    10021 ctcaagcagc ctacccgggt tcagtacggg ccgtacctta tgaaccccta tttggccttg
    10081 ctccgggtgg agtttaccgt gccacggact gttaccagcc gcgcggtgcg ctcttaccgc
    10141 accctttcac ccttacctga tcccgcttac gcgggccatc ggcggtttgc tctctgttgc
    10201 actggtcgtg ggtttccccc ccaggcgtta cctggcaccc tgccctatgg agcccggact
    10261 ttcctcccct ccgcccgtct cccccgaaga ggacgacgac gaagcggcga ctgtctggtc
    10321 agcttcggcg cgcagtatag agggtttgcg cgcccttgtc accccgcgtt gcgcattcca
    10381 atcgccagtg tcgcggcgat attacgtgaa gcacggcaga tattgtcata agctccgcgg
    10441 agtgcttcgt ctaacgtacc aatgctggtc agtacgctga agaccgcatc aatgccatgc
    10501 tgatgtacaa cgccaacatc attggtcagg ctacccgcaa tgccaatcac cggtttatgg
    10561 tacttcttcg ccacgtttgc gacaccaatc ggtaccttgc cgtgaatact ctggctatca
    10621 atacgccctt caccagtgat caccagcgta caatcgtgaa tatgttcctc cagattcagc
    10681 gccgtagtga cgatttcaat accacttttc agttctgcac caagaaacgc catcagcgcc
    10741 gcgcccatac ctcccgcagc tcctgcgccg gggacatctt tcacatcaac atgcagcgct
    10801 tttttaataa catcggcata gtgagagagg ttattgtcca gctcgacaat catcgcctca
    10861 ctggctccct tttgtgggcc aaagatgcgc gaagcaccac tgtcgccgac taacgggttg
    10921 gtgacatcac aagcgacgcg gatgacacaa tcttttaagc gcggatcgag accggaaata
    10981 tcaatatcat tcagagtatt aagactaccg ccgccaaaac caatttcatt gccgttggca
    11041 tcgcataatt tcgcccccag cgcctgtacc atgcctgcgc cgccgtcgtt ggtggcgctg
    11101 ccgccaatgc cgataataat gtttgtcgca ccgctctcca gcgcctgcag gattaactca
    11161 ccagtaccgc gtgaagtggt cacgagtgga tcgcgttttt ccgcaggtac cagttccagc
    11221 ccactggccg ccgccatttc gataaacgcg gttttgccat cgccggagat cccccaactg
    11281 gcattcactt tctcgcccag cggccctgta accctggcgt gacgttcagc cccctgggtg
    11341 gctgcaatca tcgcttccac cgttccttca ccaccgtcgg caaccggaac agaaacatac
    11401 tgtgcatcag gaaaaatttc ccgaaatcct ttttctatcg cctgcgcaac ctcgctggca
    11461 gataaacttt ctttataaga gtctggggcg attacgattt tcatacctat gcctgttacc
    11521 acatgacgcc ggagggcgtt tctcttattc ggcctggatt ccaggcccgg attgcaatac
    11581 gccatccggg cacgacgtca ttagcgagta acttcgactt tcgccagttt ttcgtagtag
    11641 cacgccaggg cgctatgatc cgccgttcct aaaccatctg cacgcagtgc ctgcatcatc
    11701 tccataaccg cagcagtgag cggcagttgc gcgccgacgc cgtgagaagt atccagcgca
    11761 ttcgccagat ccttaatatg cagatcaata cggaagcccg gtttgaagtt gcggtccatc
    11821 accatcggcg ctttggcatc cagcacggta ctgcccgcca gcccaccgcg aattgcctga
    11881 tacaccagat ccgggttaac gcccgctttg gttgccagcg ttaacgcttc tgacatcgcg
    11941 gcaatattca gcgccacaat gacctgattt gccagtttgg tgacgttacc tgcaccgatt
    12001 tccccggtat gcaccacgga acccgccatc gctttcatca aatcatagta tttgtcgaaa
    12061 atagccttgt cgccgcccac catcactgac agcgtaccgt cgatggcttt cggttcaccg
    12121 ccgctcaccg gagcatccag catatcaatg cctttcgctt tcagcgcttc gctgatttca
    12181 cggcttgcca gcggtgcgat agaactcata tcgatcaata ccgtacctgg cttcgcgcct
    12241 tcaataatgc cattctcacc cagcgccacc tctttcacat gaggggagtt tggcagcatg
    12301 gttatgatga cgtcgcactg ttcagcgatc gctttagccg tagcggctgt ttctgcaccg
    12361 gcagcaatca cgtcagcaat agcttctggg ttacggtcag caaccaccag cgagtaacct
    12421 gctttcagaa ggtttttact cattggttta cccataatcc ccaggccaat aaaaccaact
    12481 ttcatagtca tatcaatcat ctctcttgtt gcggtggtgg ttatttttta aaggtatcag
    12541 ccagtttctg agtggcagag cggaagacgc cgagatcgct gccgacggcc acaaacgtcg
    12601 cgccccattc cagataacga cgcgcatcag cctcgaccgg tgcgaggatg ccgctgggtt
    12661 tgccgtgcgc gctggcacgg ttaaaaatgt gctgaattgc tttttgtaca tccgggtgcg
    12721 aggcattgcc gagatggcct aatgccgcag ccagatcgct ggggccgacg aagatgccgt
    12781 ctacaccttc ggtagcggca atagcatcga cgttatctac gccctgctga ctttctatct
    12841 ggaccagaat agtgatgttc ttgttcgact gagcgaaata atccgccacg gtgccaaaca
    12901 tattggcgcg gtgagaaacg gagacgccgc gaatgccttc cggtgggtaa cgagttgatg
    12961 ccaccgcctg ctctgcttcc tcttttgttt ctacaaaagg aatcaggaag ttatagaaac
    13021 cgatatccag aagacgctta ataattaccg gctcgttggt cggcactcgc actactggcg
    13081 cgctggcgct gcctttcagg gccattaact gcggaataaa cgtggagata tcgtttggcg
    13141 catgttcacc atccagcacc agccagtcaa acccagccaa accaagaact tcagtgctaa
    13201 tcgggttaga gagagctgac cagcaaccaa tttgtacctg tttcgcagcc agtgcggctt
    13261 tgaatttatt cgggaaaaca tcgttattca tcgcttatac ctttgcttat ttctgcaatt
    13321 ccatacgttt aatgtcgccg actacgaaga ggtagcagac catcgccatc agcgctgaac
    13381 atcccacgaa aaccagtgct gcattgaagg agtgcagttc acttaccaga tagccaatca
    13441 ccagtggagt gacaatggag gcaacattgc caaagacgtt aaagacgccg ccgcagaggc
    13501 caacaatctc tttcggcgcg gtgtcagaaa tcactggcca gcccagcgca ccaaatcctt
    13561 tgccaaagaa agccagcgcc atcagcatga ccaccagcgt ggtgttgttg gtgtagttac
    13621 ataagatgat ggtggaagcc agcaacattc ccagcacaat tggtagctta cgtgccaggg
    13681 tcagggacaa accgcgtttg atcagataat ccgagaagac acctcccagc acgccgcccg
    13741 caaagccaca cagtgccgga atcgaggcga ccagacccac tttcagaatc gacatgcctt
    13801 tttcctgcac cagataaatt gggaaccagg tgaggaagaa ccaggtgatg gtgttgataa
    13861 aatattgtcc gaaaaatacg cccagcatca tgcggttaga gagcaattgc ttgatgtaat
    13921 gcagtttggg tccgcttgct gccgcactac ccggcttttt gtggtccata tcgaccaccg
    13981 cgccattttc cgagataaac ttcagctctt ctgcagacat acgtgggtga tctgtcgggt
    14041 tatgaatcaa cttgatccac agcgccgtca acacaaaacc aatcaccccc ataacggtaa
    14101 agacatgctc ccagccccag gcgaaagtca gccagccaag cagcggcgaa aagagcgcca
    14161 acgagaaata ttgcgccgag ttaaagatgg cggaggcagt accacgttct ttcgtcggga
    14221 accaggcggc gacaatacgg gcgttcgccg ggaatgatgg cgcttccgag aaccccagca
    14281 taaatcgcat aaagaacatg gagatcccag cccaggccag cggaaacata tcgacaaagc
    14341 cttgcaggaa ggtgaacagc gaccagaaaa agaggctgta agtgtaaact ttcttcgagc
    14401 caaacttatc aagcagccag ccgccgggaa tttgcatcag caagtaggcc cagccaaaag
    14461 cagagaagat gtaacccatc gaaaccgcac ttaactgcaa ctcttttgcc acttcggtac
    14521 cagcaataga cagcgttgca cgatcggcgt agttaacggc ggtaacaata aaaataatca
    14581 gtaatattaa atagcgggta tgcacgcctt tcttttttac gtcaacggtg tcca
//
LOCUS       DAPOXO010000108        14120 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.108, whole genome shotgun sequence.
ACCESSION   DAPOXO010000108 DAPOXO010000000
VERSION     DAPOXO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14120
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.108"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(221..1870)
                     /gene="pgi"
                     /locus_tag="ROH59_004302"
     CDS             complement(221..1870)
                     /gene="pgi"
                     /locus_tag="ROH59_004302"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDX4806708.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            2395..3744
                     /gene="lysC"
                     /locus_tag="ROH59_004303"
     CDS             2395..3744
                     /gene="lysC"
                     /locus_tag="ROH59_004303"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HDX4806709.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDVA
                     ALAELAALQLLPRLNEGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHFNLFE"
     gene            3997..4269
                     /locus_tag="ROH59_004304"
     CDS             3997..4269
                     /locus_tag="ROH59_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HDX4806710.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKK
                     EYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSWSANTSTRGRR"
     gene            complement(4270..5142)
                     /gene="rluF"
                     /locus_tag="ROH59_004305"
     CDS             complement(4270..5142)
                     /gene="rluF"
                     /locus_tag="ROH59_004305"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HDX4806711.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKSGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEAKPKAKAKPKTVGIKRPVVKMEKTAEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            5490..6437
                     /locus_tag="ROH59_004306"
     CDS             5490..6437
                     /locus_tag="ROH59_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDX4806712.1"
                     /translation="MENSDDIRLIVKIAQLYYEQDMTQAQIARELGIYRTTISRLLKR
                     GRDQGIVTIAINYDYNENLWLEQQVKQKFGLKDVVVVSGNDEDEDTQLAMMGLHGAQL
                     LDRLLEPGDIVGFSWGRAVSALVENLPQAGQSRQLICVPIIGGPSGKLESRYHVNTLT
                     YSAAAKLKGESHLADFPALLDNPLIRNGIMQSQHFKTISAYWDNLDVALVGIGSPAIR
                     DGANWHAFYGGEESDDLNARQVAGDICSRFFDIHGAMVETNMSEKTLSIEMNKLKQAR
                     YSIGIAMSEEKYSGIVGALRGKYINCLVTNSSTAELLLK"
     gene            6507..7313
                     /locus_tag="ROH59_004307"
     CDS             6507..7313
                     /locus_tag="ROH59_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX4806713.1"
                     /translation="MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGG
                     DGQYESHKGYQFWPTDISSAKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAP
                     AGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC
                     YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQ
                     LREGYTKNAIPIGRAGRLAEVADFVCYLLSERASYITGVTTNIAGGKTRG"
     gene            7323..7730
                     /locus_tag="ROH59_004308"
     CDS             7323..7730
                     /locus_tag="ROH59_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIA"
                     /protein_id="HDX4806714.1"
                     /translation="MVNAIFCAHGKLACAMLESVQMVYGDARVEAVEFVPGENAGDIV
                     AKLEKLVSIHNQDEWLIAVDLQCGSPWNAAAMLAMRNPRLRVISGLSLPLALELVDNQ
                     DSMNVDELCEHLTQIAKQTCVVWRQVATAEEDF"
     gene            7730..8224
                     /locus_tag="ROH59_004309"
     CDS             7730..8224
                     /locus_tag="ROH59_004309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HDX4806715.1"
                     /translation="MNITLARIDDRLIHGQVTTVWSKVANAQRIIICNDEVYNDEVRR
                     TLLRQAAPPGMKVNVVNIEKAVAVYHNPQYQDETVFYLFTRPQDALAMVRQGVKIGTL
                     NIGGMAWRPGKKQLTKAVSLDDDDINAFHELNNLGVILDLRVVASDPSINIIDKINEQ
                     LIAN"
     gene            8290..9087
                     /locus_tag="ROH59_004310"
     CDS             8290..9087
                     /locus_tag="ROH59_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HDX4806716.1"
                     /translation="MEISTLQIIAIFLFSCIAGMGSVLDEFQTHRPLIACTVIGLILG
                     DLKTGIMLGGTLELIALGWMNVGAAQSPDSALASIISAILVIVGQQSIATGIAIALPV
                     AAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDILHVSALGVQALRVAIPALIVSL
                     FVSADMVSNMLSAIPEFVTRGLQIAGGFIVVVGYAMVLRMMGVKYLMPFFFLGFLAGG
                     YLDLSLLAFGGVGVIMALLYIQLNPQWRKAEPHPQTTTITALDQLDD"
     gene            9098..9922
                     /locus_tag="ROH59_004311"
     CDS             9098..9922
                     /locus_tag="ROH59_004311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDX4806717.1"
                     /translation="MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIK
                     RLYPLKEDQVAALRRHLVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVG
                     LMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNVVRLAMKWYGLQL
                     GFRKGVNIVSDMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGAT
                     VTITVQNILDQLCPGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS"
     gene            9974..11203
                     /gene="sorE"
                     /locus_tag="ROH59_004312"
     CDS             9974..11203
                     /gene="sorE"
                     /locus_tag="ROH59_004312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-sorbose 1-phosphate reductase"
                     /protein_id="HDX4806718.1"
                     /translation="MKTTALRLYGKRDLRLETFDLPEMQEDEILATVVTDSLCLSSWK
                     EANLGENHKKVPDDVATNPIIIGHEFCGDILAVGKKWQHKFQPGQRYVIQANLQLPDR
                     PDCPGYSFPWVGGEATHVVIPNEVMEQDCLLAYDGETYFEGSLVEPLSCVIGAFNANY
                     HLQEGSYNHTMGIRPQGRTLILGGTGPMGLLAIDYALHGPVNPSLLVITDTDNDKLSY
                     ARKHYPSEPQTLIHYLNAADAAFDTLMALSGGHGFDDIFVFVPNEGLVTLASSLLATD
                     GCLNFFAGPQDKHFSAPINFYDVHYAFTHYVGTSGGNTDDMRAAVKLIEEKKVQAAKV
                     VTHILGLNAAGETTLELPAVGGGKKLVYTGKYLPLTSLTQIQDQALAAILARHQGIWS
                     GEAEQYLLAHAEAISHD"
     gene            11585..12274
                     /gene="pepE"
                     /locus_tag="ROH59_004313"
     CDS             11585..12274
                     /gene="pepE"
                     /locus_tag="ROH59_004313"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HDX4806719.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIIDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(12364..13995)
                     /locus_tag="ROH59_004314"
     CDS             complement(12364..13995)
                     /locus_tag="ROH59_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDX4806720.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLPLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
BASE COUNT         3405 a         3569 c         3714 g         3432 t
ORIGIN      
        1 ttaaatgaca gacaagagga tttatctgat aaaacaatgc cgacttatag tcggcattgt
       61 ttttaaggct atttaatcaa tcgtactatg tattaattgc cgaatacgat gtacatatcg
      121 gcatcgacct gtaggcctga taagacgcga ccgcgtcgca tcaggcatcg gttgccggat
      181 gcggcgtgaa cgccttatcc ggcctacata tcgacaatga ttaaccgcgc cacgctttat
      241 agcggttaat cagaccattg gtcgagctat cgtggctgct gatttctttg tcatctttca
      301 gctctggcag aatacggttc gccagttgtt tacccagctc cacgccccat tggtcgaagg
      361 tgaagatgtt caggatcacg ccctgagtaa agattttgtg ctcatacagc gcaatcaacg
      421 cccccaggct gaacggagtg atttcacgca gcaggatgga gttggtcggg cggttacctt
      481 cgaacacttt gaacggcacc acgtagtcaa gcgttgccgg atctttaccc tgatcgcgat
      541 attcctgctc aaccacttcg cgggatttac caaacgccag cgcttcggtc tgagcaaaga
      601 agttagacag cagtttctgg tgatgatcag agagcgggtt atgggtgata gccggagcga
      661 tgaaatcgca cggtaccatt ttggttccct ggtggatcag ctgatagaac gcgtgctgac
      721 cgttcgtgcc aggttcaccc cagataatcg ggccagtctg gtaatccaca accttaccgt
      781 tacggtcaac atacttaccg ttggattcca tattgccctg ctggaagtac gccgcgaaac
      841 ggtgcatata ctggtcatac ggcagaatcg cttcagtttc cgcgccaaag aaattgttgt
      901 accagatgcc aatcagcgcc agcagtacag gcaggttttt ctcggcaggc gtggtggaga
      961 aatgcttgtc catcgcgtgt gcgccagaaa gcagttcaac gaagttatca aagccgatgg
     1021 agagaacaat cgacaggcca atcgctgacc acaaagaata acgaccgccg acccagtccc
     1081 agaattcgaa catgttggca gtatcaatac caaactcgcc aacggctttg gcgttggtgg
     1141 aaagcgccgc aaagtgtttc gcaacgtgct tctcatcacc tgccgctttc aggaaccagt
     1201 cacgcgcgct atgggcgttg gtcatggttt cctgagtggt gaaggtttta gatgctacca
     1261 ggaacagcgt ggtttccggg tttacttttt tcagcacttc cgcgatgtga gtcccatcga
     1321 cgttagaaac aaagtgcatg ttcaggtggt ttttgtatgg acgcagtgct tcagtcacca
     1381 tgtacgggcc gaggtcagaa ccgccgatcc cgatgttcac tacgtcagtg attgccttgc
     1441 cggtatagcc tttccactca ccggaaataa tcgcttccga gaaggttttc atcttctcca
     1501 gcaccgcgtt gacttccggc ataacatctt tgccatcaac cagaatcggg gtattgctac
     1561 ggttacgcag cgctacgtgc agtacggcgc ggttttcagt gcggttgatc ttctcgccag
     1621 agaacatcga cttaatcgcg cccgccagat cgcactcttt cgccagatct tgtaatttcg
     1681 ccagcgtctc ttcagtgatg cggtttttgg agtaatccac cagcatctga tcgtcgaagg
     1741 ttgcggagaa cttagaaaaa cgatcgccgt ctttagcaaa aagatcggcg atcgtaacgt
     1801 ctttcatttc atcgaagtgt ttctgtagtg cctgccaggc agcggtctgc gttggattga
     1861 tgtttttcat tagcaatact cttctgattt tgagaattgt gactttggaa gattgtagcg
     1921 ccagtcacag aaaaatgtga tggttttagt gccgttagcg taatgttgag tgtaaaccct
     1981 tagcgcagcg aagcatttat tagctgaact actgaccgcc aggtgtggat gaaaaatccg
     2041 catgacccca ccgttgacaa ccgccccgct caccctttat ttataaatgt actacctgcg
     2101 ctagcgcagg ccagaagagg cgcgttgccc aagtaacggt gttggaggag ccagtcctgt
     2161 gataacacct gagggggtgc atcgccgagg tgattgaacg gctggctacg ttcatcatcg
     2221 gctacagggg ctgaatcccc tgggttgtca ccagaagcgt tcgcagtcgg gcgtttcgca
     2281 agtggtggag cacttctggg tgaaaatagt agcgaagtat cgctctgcgc ccacccgtct
     2341 tccgctcttc ccttgtgcca aggctgaaaa tggatcccct gacacgaggt agttatgtct
     2401 gaaattgttg tctccaaatt tggcggtacc agcgtagctg attttgacgc catgaaccgc
     2461 agcgctgata ttgtgctttc tgatgccaac gtacgtttag ttgtcctctc ggcttctgct
     2521 ggtatcacta atctactggt cgctttagct gaaggactgg aacctggcga gcgattcgaa
     2581 aaactcgacg caatccgcaa tatccagttt gccattctgg aacgtctgcg ttacccgaac
     2641 gttatccgtg aagagattga acgcctgctg gagaacatta ccgttctggc agaagcggcg
     2701 gcgctggcaa cgtctccggc cctgacagat gaactggtca gccacggcga gctgatgtcg
     2761 accctgctgt ttgtcgagat cctgcgcgaa cgcgatgttc aggcacagtg gtttgatgta
     2821 cgtaaagtga tgcgtaccaa cgaccgattt ggtcgtgcag agccagatgt agccgcgctg
     2881 gcggaactgg ccgcgctgca gctgctccca cgcctcaatg aaggcttagt gatcacccag
     2941 ggatttatcg gcagcgaaaa taaaggtcgt acaacgacgc ttggccgtgg aggcagcgat
     3001 tatacggcag ccttgctggc ggaggcttta cacgcatctc gtgttgatat ctggaccgac
     3061 gtcccgggca tctacaccac cgatccacgc gtggtttctg cagcaaaacg cattgatgaa
     3121 atcgcgtttg ccgaagcggc agagatggca acttttggtg caaaagtact gcatccggca
     3181 acgttgctac ccgcagtacg cagcgatatc ccggtctttg tcggctccag caaagaccca
     3241 cgcgcaggtg gtacgctggt gtgcaataaa actgaaaatc cgccgctgtt ccgcgcgctg
     3301 gcgcttcgtc gcaatcagac tctgctcact ttgcacagcc tgaatatgct gcattctcgc
     3361 ggtttcctcg cggaagtttt cggcatcctc gcgcggcata atatttcggt agacttaatc
     3421 accacatcag aagtgagcgt ggcattaacc cttgatacca ccggttcaac ctccactggc
     3481 gatacgttgc tgacgcaatc cctgctgatg gagctttccg cactgtgccg ggtggaagtg
     3541 gaagagggtc tggcgctggt cgcgttgatt ggcaatgacc tgtcaaaagc ctgcggcgtt
     3601 ggcaaagagg tattcggcgt actggaaccg ttcaacattc gcatgatttg ttacggcgca
     3661 tccagccata acctgtgctt cctggtgccc ggcgaagatg ccgagcaggt ggtgcagaag
     3721 ctacatttta atttgtttga gtaaacacag tatggcccgg aagacattat ttcgggccgt
     3781 attgtttttc ttgtcattat gcccataaat aaacgagcct gtactctgtt aaccagcgtc
     3841 tttatcggag aataattgcc tttaattttt tatccgcatc tctaactaat tatcgaaaga
     3901 gataaatagt taagagaagg caaaatgaat attatcagtt ctgctcgcaa acgaattccc
     3961 gtacactgaa ctctctggct cactgagggc accatcatgg cactcccccg tattacccaa
     4021 aaagagatga ctgaacgcga gcagcgtgaa cttaaaacac tgctggatcg ggcgcggatt
     4081 gcgcatggtc gcgtactgac caactccgaa accaacagca ttaagaaaga gtacatcgat
     4141 aaattaatgg tcgagcgtga ggctgaagcg aaaaaagccc gccaattgaa gaaaaagcag
     4201 gcttataaac cggatcctga ggcgtcattt agctggtcag caaatacgtc gacgcgcggc
     4261 aggcgctgat taacgcccct tctttttgcg ccccggcgag gtaaaacgct taccgttgga
     4321 cgccgggcga ccgccttttt ccgccgtttt ttccatctta acgactggac gtttgatgcc
     4381 taccgttttc ggtttggcct tcgctttagg ttttgcctcg gaagaggaat tttcaatgag
     4441 cttaaagaga tcgattaact catcgtcggt taaatcgcgc cactcaccca gcggaatgcc
     4501 gcttaagctg acgttcataa tgcgcgtacg ttccagcttt ttcacttcgt aaccaaagtg
     4561 ctcgcacatg cgacgaatct gacggttcag cccctgcacc agggtaatgc ggaagacaaa
     4621 cggtgcttct tttttgactt tgcacttttt agttaccgtc ccgaggatcg gcactcccgc
     4681 ccccatacca cgaataaatt catcggtaat cggtttatca accgtcacca gatactcttt
     4741 ctcatgatcg ttacccgcac ggaggatctt attcactaga tcgccgtgat tggtgaggaa
     4801 aatcagcccc tgggaatctt tatccaggcg gccaatcggg aacacgcgtt tgctgtggtt
     4861 aacgaaatcg acaatgttat cgcgctcgcc atcttcggtg gtgctgacaa tgcctacggg
     4921 cttgttcagg gcgataagta ccaaatcttc ggcttcccga ggctcaatca actgaccgtt
     4981 tactttcaca acgtcgccgg atttcacctg atcgccaatg gtggctcgct tgccattaag
     5041 gaacacattg ccttgctcga tatagcgatc cgcttcgcgg cgtgagcaaa ttccgctttc
     5101 gctgatgtat ttatttaaac ggactgatga gtcgggcagc ataaattctc ctgtaaaacg
     5161 cggaatatac cgtacctctt agcggggaaa aacagggtta tgcggcaacg tcgaaattaa
     5221 atgtgatctg ccacgccttt tatcacaaaa gtgtctccgg aagtacgatg caaatttgcc
     5281 tggcaaaata aggataatca acaaattacg aatcgctgca cacctgtgct gatgactact
     5341 acgcagagaa acaaatgtgc aagagaaagc gctatttccc cccatgcaaa gagtgaaaaa
     5401 tcgctttgaa aggccatcat gatggggtta tatcagatca agcggtgaga aagcgtattt
     5461 gcacaaatgt gcagaaccag gaggcggcaa tggaaaacag tgacgatatc cgtttgattg
     5521 tgaagattgc ccaactctat tacgaacagg atatgacgca ggcgcaaatt gcgcgcgaac
     5581 tgggtattta ccgcaccacc atcagccgct tgcttaaacg aggccgcgat cagggaattg
     5641 tcaccatcgc catcaactat gactacaacg aaaatctctg gctggagcag caagtgaagc
     5701 aaaagtttgg cctgaaagac gttgtggtgg tgtcaggaaa tgatgaggat gaagatactc
     5761 aactggcgat gatggggtta cacggcgcgc aactgctgga tcgcttgctg gaacctggtg
     5821 atattgttgg tttttcctgg ggtcgcgcgg tgagcgcact ggttgaaaac ttgccgcagg
     5881 cggggcaatc gcggcagtta atttgcgtgc cgattattgg cggcccgtcc ggtaaactcg
     5941 aaagccgcta tcacgtaaac acattaacct acagcgcggc agcgaagctg aaaggggaat
     6001 cgcatctcgc ggattttccg gctctgctgg ataacccatt aattcgtaat gggatcatgc
     6061 agtctcagca ctttaaaacc atctctgcct actgggataa tctggatgtc gccctggtgg
     6121 gaattggctc accggccatt cgcgacggcg ctaactggca tgcgttttat ggtggtgaag
     6181 agagtgacga cctgaatgcc cgccaggttg ctggcgatat ttgctcgcgc ttttttgata
     6241 ttcacggcgc aatggttgaa acgaatatga gcgaaaaaac actctctatc gaaatgaata
     6301 aattaaagca ggcacggtat tccattggca ttgccatgag cgaagaaaaa tacagcggaa
     6361 ttgttggtgc actgcgtgga aaatatatta attgtctggt aacgaatagc agcacagctg
     6421 aactattact gaaataaaaa tcttcccgat gtttaccgta ataaaaatta cggcgggtcc
     6481 ttattatcta aaatcaggag tctgttatgc aaacgtggtt aaatttgcag gataaaatca
     6541 ttattgtcac cggtggcgca tccggcattg gtctggcgat tgtggatgaa ttattagcac
     6601 aaggcgcgaa tgtacagatg gtcgatattc acggtggcga tggtcagtat gaaagccata
     6661 aaggttatca gttctggccg accgatattt ccagcgccaa agaggtaaat catacggtag
     6721 cagaaattat ccagcgtttt ggtcgcatcg acggtctggt taacaacgcc ggggtcaatt
     6781 tcccgcgtct gctggtcgat gagaaagcgc ctgccgggca gtatgaactc aacgaagctg
     6841 cattcgaaaa aatggtcaat atcaaccaga aaggcgtttt tctgatgtcg caggcggtgg
     6901 cgcgacagat ggtcaaacaa catgatggcg tgattgtgaa tgtttcctca gaaagtgggc
     6961 tggaaggctc agaaggccaa agctgttacg ccgcgaccaa agccgcgctc aatagcttca
     7021 cgcgctcctg gtcgaaagag ctgggtaagc acggtatccg tgtggtcggt atcgcgccgg
     7081 ggattctgga aaaaacaggg ctgcgcacgc cggaatatga agaggcgctg gcgtggacgc
     7141 gcaatatcac cgtcgagcag ctgcgtgaag gctataccaa aaacgccatt cctattgggc
     7201 gcgccggaag attagcagaa gtggctgatt ttgtttgtta tctgctgtct gaacgcgcca
     7261 gctatatcac cggagtaacc actaacattg cgggcggcaa aacgcgcggc taaggaggct
     7321 ttatggtcaa tgccattttt tgtgcgcatg gcaaattagc ttgcgccatg ctggaatcgg
     7381 ttcagatggt ttacggcgat gccagggtcg aggcagttga atttgtgccc ggcgagaacg
     7441 ccggagacat cgtagcaaag ctggaaaagt tagtaagcat tcacaatcaa gatgagtggc
     7501 tgattgccgt ggatttacag tgcggcagcc cgtggaatgc ggcagcgatg cttgcgatgc
     7561 gcaatcctcg tctgcgggta atcagcggcc tttctctgcc gctagcgctc gaactggttg
     7621 ataaccagga cagcatgaat gttgatgaac tgtgtgaaca cctgacgcaa atcgcaaagc
     7681 aaacctgcgt cgtctggaga caggtggcaa cagcggagga ggatttctga tgaacattac
     7741 gctcgcccgc attgatgacc gcctgatcca cggccaggtc actaccgtct ggtctaaagt
     7801 ggctaacgcc cagcgcatta ttatctgcaa tgacgaagtt tataacgatg aagttcgccg
     7861 gacattattg cgtcaggctg cgccaccggg aatgaaggtt aacgtggtca atattgaaaa
     7921 agccgtcgcg gtgtatcaca acccgcaata tcaggacgaa accgtttttt atcttttcac
     7981 tcgcccacag gatgccttag caatggttcg ccagggggta aaaataggta ccctgaatat
     8041 tggcggcatg gcctggcgtc ctggtaaaaa acagttaacc aaagcagttt cattagatga
     8101 cgatgatatt aacgcatttc atgagttaaa taatcttggc gtcatactgg atttacgcgt
     8161 cgtagcgtca gatccctcaa tcaatattat cgacaaaata aatgaacagt taatcgcgaa
     8221 ttaaataata gcgcctgtgt acatatgctt taacaggcag ggatgacgac acttaaaagg
     8281 tgacaaatca tggaaataag tactctacaa atcattgcta tatttctttt ttcctgtatt
     8341 gccggaatgg gcagcgtgct ggatgaattt cagactcatc gtccgttaat tgcctgtacg
     8401 gtgattggtt taattctcgg tgatttaaaa accggaatta tgctcggtgg tacgctggaa
     8461 ttgatagctc tcggctggat gaacgtcggc gcggcgcaat ctccggattc tgcgctcgcc
     8521 agcataatct ccgccattct ggttatcgtt ggtcagcaaa gcatcgccac cggaatcgcc
     8581 atcgcgttgc ctgtggctgc ggcaggccag gtgctgacgg tgtttgcccg taccatcacc
     8641 gtagtgttcc agcacgcggc ggataaagca gcggaagaag cacggtttcg cactctcgat
     8701 attctgcatg tctccgcgct tggcgtgcag gcactgcgcg ttgctattcc ggcactgatt
     8761 gtctcgctgt tcgtcagcgc tgatatggtg agcaatatgc tgagcgccat tcccgaattt
     8821 gtgacccgtg gactgcagat tgctggcggt tttatcgtgg tggtcggtta cgccatggtg
     8881 cttcgcatga tgggcgtgaa atatttgatg cctttctttt tcctcggttt cctcgcaggt
     8941 ggctacctcg atctcagtct gctggcgttc ggtggcgtcg gcgtgatcat ggccctgctc
     9001 tacatccagt taaatccaca gtggcgtaaa gctgaaccac atccccagac caccactatc
     9061 accgcccttg accaacttga tgattaacgg agccatcatg gaacagagaa aaattacacg
     9121 cagcgatctg gtgagcatgt ttctgcgctc caacctgcaa caggcatcct ttaactttga
     9181 acgtattcac gggctgggtt tttgctacga catgatcccc gccatcaaac gactttaccc
     9241 attaaaagag gatcaggttg cggcgctcag gcgacacctg gtgttcttca ataccacgcc
     9301 agccgtatgt ggcccggtca tcggcgtcac tgccgccatg gaagaggcgc gagccaacgg
     9361 cgcggaaatt gatgacggta ccattaacgg catcaaagtc ggtctgatgg gaccattggc
     9421 aggagttggc gatccactgg tctggggaac gctgcgcccg attaccgccg cgctcggcgc
     9481 atctctggca ctttcgggca acattctcgg ccccctgctg ttcttcttta ttttcaacgt
     9541 ggtgcgcctg gcgatgaagt ggtatggcct acagctcggc tttcgcaaag gggtgaatat
     9601 cgtcagcgat atgggcggta atttgctgca aaaactcacc gaaggcgcgt cgattctcgg
     9661 gctgtttgtg atgggcgtgc tggtgaccaa atggacgtca atcaacgtac cgttggtggt
     9721 ttcacaaacg cctgccgccg atggtgccac cgtcaccata accgtgcaga acatcctcga
     9781 ccaactttgc cctggtttgc tggcgctcgg tctgacgctg ctgatggttc gtctgctcaa
     9841 caaaaaaatt aacccggtat ggctgatttt cgccctgttt ggtttaggga ttatcggtaa
     9901 tgcgctgggc ttcctgtcct gattcttcgc cccggcgcaa ccgtcggggc catcgttcaa
     9961 cacgaggtgg tttatgaaaa caacagctct gcgtctttat ggtaaacgtg atttacgcct
    10021 ggaaaccttt gaccttcctg aaatgcagga ggatgaaatc ctcgcaacgg tggtcactga
    10081 cagcctgtgc ctctcttcct ggaaagaggc caatctgggt gaaaatcata aaaaagtacc
    10141 cgacgatgtg gcgaccaatc ccatcatcat cggccacgaa ttttgcggcg atattctggc
    10201 cgtgggtaaa aagtggcagc acaaattcca gccgggtcag cgttatgtga ttcaggccaa
    10261 cctgcaactc cccgaccgcc cggattgccc cggctactcc ttcccgtggg taggcggcga
    10321 agcgacgcat gtggttattc ccaacgaggt catggaacaa gattgcctgc tggcatacga
    10381 cggcgaaacc tattttgaag gctcgctggt tgaaccgctt tcctgcgtga ttggcgcgtt
    10441 caacgccaac tatcatcttc aggaaggtag ttataaccac acgatgggga ttcgcccgca
    10501 agggcgcacg ctgatcctcg gcggcaccgg accaatggga ctgttggcga ttgattatgc
    10561 gctacatgga cccgttaacc cttcgctgct cgtcattacc gataccgaca acgacaaatt
    10621 gagttatgcg cgcaagcact atccatcaga accgcaaaca ctgattcatt atctcaatgc
    10681 cgccgatgca gcatttgata cgttaatggc actgagtggc ggtcacggct tcgatgatat
    10741 tttcgtcttt gtgcctaatg aaggactggt gactctcgcc tcttccttgc tggcgacaga
    10801 tggttgtctg aatttcttcg ccggaccgca ggataagcac ttcagcgcgc caattaattt
    10861 ctacgatgtg cattatgcat ttacccacta cgtgggcacg tcaggcggca ataccgacga
    10921 catgcgcgca gcggtcaaat taattgaaga gaaaaaagtg caggccgcaa aagtggtaac
    10981 acatattctt gggctgaatg ccgcgggcga aaccacgctt gaattgcctg ccgtcggcgg
    11041 cggcaaaaag ctggtgtata ccgggaaata cctgccgctg acgtcactca cgcagattca
    11101 ggatcaagca ctggcggcga ttctggcgcg tcatcagggg atctggtccg gtgaggcgga
    11161 gcaatacctg ctcgcccatg cagaggcaat ttcccatgat taatcgcgct acttaactct
    11221 gcatgtcgct ggctggtcgc cgcggcaact tcgcgacctg atgtgcggct gattgctgaa
    11281 gcggcacaat gtgcacgaga aggataaaaa aacatcagcg ccttaagggg cgctcaaatt
    11341 ggtggcaaag tgcacattgt ttatgccgga tgcggaatga agccttattc ggcctacata
    11401 atcttgaaaa ttcaatatat tgcagttatc tggtaggcca ggtaagcgta gcgcatcagg
    11461 caatcctgtg tttgtcatca gtctcagcgc ctgtgcaata tgtgacatcg tgagccatgt
    11521 cagtaagtgg ttaaattcgc agtggtagca ttccttccgt gttttcttac taaccggaga
    11581 agtaatggaa ctgcttttat tgagtaactc gacgctgccg ggtaaagcct ggctggaaca
    11641 cgcgctgccg ctgattgctg aacagttgca gggtcgccgt tctgcggtat ttattccttt
    11701 cgctggcgta acgcagacct gggatgatta cacagcgaaa acggctgcgg ttctcgctcc
    11761 gctgggtgtt tctgtcaccg gtattcatag cgttgtcgat cccgttgccg cgattgaaaa
    11821 tgcggaaatt gtgattgtcg gcggcggtaa tactttccag ttgctgaaac agtgccgcga
    11881 gcgcgggctg ctggcaccca ttactgacgt ggtgaaacgt ggcgcgctgt atattggctg
    11941 gagcgcaggc gctaaccttg cttgcccaac cattcgtacc accaacgata tgccgattat
    12001 cgatccgcaa ggtttcgatg cgctaaatct gttcccgcta caaatcaacc cgcacttcac
    12061 caacgcgctg ccggaaggcc ataaaggtga aacccgtgag cagcgtattc gcgaactgct
    12121 ggtcgtcgcg ccagaactga cgattattgg tctgccggaa ggtaactgga tcacagtaag
    12181 taaaggtcac gctacgctgg gtggcccgaa caccacttat gtatttaagg ctggtgaaga
    12241 agcggtgccg ctggaagcgg gtcaccgttt ttaagtgaat tgccggatgc atgatccggc
    12301 atcttgttca tagtgcctga tgcaacgctt tacgcgtctt atcaggcctt cagggtcacg
    12361 gtattaatac tcgtcccgtc cttcatcttc atccggctgt tccagcacac tgtaagccac
    12421 cgaacaaaac agcgagttca gacgctgcat atctcccagt aagcctaaat gtagcgaact
    12481 ggtttcaata ctctgcacgt tttgctggtg caggcgatcg acgtgggcgt gggaatagcg
    12541 gcgattaaga atgcgaaaac gatgtttgct gcggcgcaaa cgacgggcgc tggtaacatc
    12601 gccagagaag aaaaccgaca ttgccagttt taaattactg agcaattgct catagagcgc
    12661 atccagttcc ttcaagccat caagcgaaaa tgctcgcctt gctgccagcg atttgtcggc
    12721 aatttcgctg cccatgcgct cgacgatatc ggaggcctgt tcaaggttga gcgacatttc
    12781 gatgatctcc gcccagcggc gcgactcttc ttctgccagt tcctcttttg gcatccgcgc
    12841 cagatacagc ttaatggcgg tatagagaac gttgatgtca tcagccagct tacgcagctc
    12901 tttctcctgc cgtggctcgc cgtgcatcac tttattcagc ccttccatca tctgttccat
    12961 ggcgtcgcca atgcgcaggg tttcgcgggc agcgttcgcc agagcaagcg tgggcgtatc
    13021 cagcgcgctg acatccagat gtttaggccg tagctgggta tccagttccg gttcatcgcg
    13081 aataatcgtt ttgcaaaacc gtgccatcgg gtcaacgaat ggcaacatga ccaggcagcg
    13141 tacaaggttg tagaagacgt ggaaatagat caccaattcc gcttttggca atggcaactt
    13201 ccccattgtc tctgccagca aatgaacaaa cggcaggata atcaggctac ccaccagctt
    13261 aaacagcagg ctacccagcg cgacacggcg ggctgcggca ttggcggcac tgttgttgag
    13321 catcgccagc aggccggaac cgaggtttgc accaatcacc agacaaagcg ccactgggaa
    13381 agagataatg cctgcggcgg tcagagtcgc ggtcagcagt accgcggcaa ggctggagta
    13441 gctgataatg gcgaacatcg caccaatcag cgcatccagc aaaatgtcgc cagtcagcga
    13501 ggcaaagatc acctgaacgc cgtttgcctg agtgatcggc gttacggcct gcacaatcaa
    13561 ctccagcgcc agtaaaatca gcccaagacc aataccgacg cggcccagtt gcccggcgcg
    13621 tgactgtttg cgtccgagga aaaaaatcac gccgataaaa ataagtaacg gtgacagcca
    13681 ggataaatcg aaggtgagaa tacgcgccat cagcgccgtc ccgacatctg cacccagcac
    13741 aatcaccagc gcaggcgcga gagcaaccag atcctgagcg acgaacgagg tcaccagcat
    13801 ggtggtggca ttactgctct gcaccagtgc ggtaacgccg atccccgcgc aaaaggcgag
    13861 cggctttttt tcgacgctcc ggctaaggac agtacgcaga cgcgcgccga agacgcgcat
    13921 tacgcctgtt cgaacaatat gggtccccca gaccagcagg gcgacggcag aaagcaggtg
    13981 aagcaaagtt agcacggaat caggttctcc tttttgttat gcattttcct gttaagattt
    14041 ttctaatcac gttgttttta tccaggcatt tctcttgtat gtactttcag tataagagat
    14101 ttatacaaga aagcatttaa
//
LOCUS       DAPOXO010000109        13946 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPOXO010000109 DAPOXO010000000
VERSION     DAPOXO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13946
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.109"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..195)
                     /locus_tag="ROH59_004315"
     CDS             complement(<1..195)
                     /locus_tag="ROH59_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001599750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806721.1"
                     /translation="MIRYSGIFLSLLMLSGCATEALKNEQAETVITAGNKAVAANASF
                     FKQYYASRENFLVNFYATNPD"
     gene            complement(365..1240)
                     /gene="rluB"
                     /locus_tag="ROH59_004316"
     CDS             complement(365..1240)
                     /gene="rluB"
                     /locus_tag="ROH59_004316"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HDX4806722.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEI
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QVSGGRRSGGRNNNG"
     gene            complement(1453..3348)
                     /locus_tag="ROH59_004317"
     CDS             complement(1453..3348)
                     /locus_tag="ROH59_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HDX4806723.1"
                     /translation="MAGIYRCILLLIVGLFFSSLSYAKNTEIPSYEEGISLFDVEATL
                     QPNGVLDIKENIHFQARNQQIKHGFYRDLPRLWMQPDGDAALLNYHIVGVTRDGISEP
                     WHLDWHIGLMSIVVGDKQRFLPQGDYHYQIHYQVKNAFLREGDSDLLIWNVTGNHWPF
                     EIYKTLFSLKLPDIAGNPFSEIDLFTGDEGDTYRNGRILEDGRIESRDPFYREDFTVL
                     YRWPHALLGNAPAPQTTNIFSHLLLPSTSSLLIWFPCLFLACGWLYLWKRRPQFTPVD
                     VIETDVIPPDYTPGMLRLDAKLVYDDKGFCADIVNLIVKGKIHLEAHYDKNQQILIRV
                     NEGATRNNAVLLPAEQLLLEALFRKGDKVVLTGRRNRVLRKAFLRMQKFYLPRKKSSF
                     YRPDAFLQWGGMAILAVILYGNLSPVGWAGMSLVGDMFIMICWLLPFLFCSLELLFAR
                     DDDKPCVNRVIITLFLPLICSGVAFYSLYINVGDVFFYWYMPAGYFSAVFLTGYLTGM
                     GYIFLPKFTQTGQQRYAHGEAIVNYLARKEAATHSGRRRKGEARKLDYALLGWAVSAN
                     LGREWAARITPSLTAAVRAPEIARSGVLFSLQMHLSLGANTSLLGRSYSGGGAGGGAG
                     GGGGGGW"
     gene            complement(3376..3996)
                     /locus_tag="ROH59_004318"
     CDS             complement(3376..3996)
                     /locus_tag="ROH59_004318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDX4806724.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            complement(3993..4874)
                     /gene="yciV"
                     /locus_tag="ROH59_004319"
     CDS             complement(3993..4874)
                     /gene="yciV"
                     /locus_tag="ROH59_004319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HDX4806725.1"
                     /translation="MSDTNYSVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQQLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLATLARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            5012..5056
                     /gene="trpL"
                     /locus_tag="ROH59_004320"
     CDS             5012..5056
                     /gene="trpL"
                     /locus_tag="ROH59_004320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HDX4806726.1"
                     /translation="MKAIFVLKGWWRTS"
     misc_feature    5033..5126
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            5148..6710
                     /gene="trpE"
                     /locus_tag="ROH59_004321"
     CDS             5148..6710
                     /gene="trpE"
                     /locus_tag="ROH59_004321"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HDX4806727.1"
                     /translation="MQTQKPTLELLTCVGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLALLDNALPAGVENEQSPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNELRQQ
                     LTEAAPPLPVVSVPHMRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGVATVQAGAGVVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     gene            6710..8305
                     /gene="trpD"
                     /locus_tag="ROH59_004322"
     CDS             6710..8305
                     /gene="trpD"
                     /locus_tag="ROH59_004322"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HDX4806728.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEQTNTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRCVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            8309..9667
                     /gene="trpCF"
                     /locus_tag="ROH59_004323"
     CDS             8309..9667
                     /gene="trpCF"
                     /locus_tag="ROH59_004323"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HDX4806729.1"
                     /translation="MQTVLAKIVADKAIWVEARKQQQPLASFQNEIQPSTRHFYDALQ
                     GARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFDFLPI
                     VSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV
                     LTEVSNEEELERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGIN
                     TYAQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVCGLTRGQDAKAAYDAGA
                     IYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLH
                     GNEDQLYIDTLREALPAHVAIWKALSVGETLPARDFQHIDKYVFDNGQGGSGQRFDWS
                     LLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLR
                     AY"
     gene            9679..10872
                     /gene="trpB"
                     /locus_tag="ROH59_004324"
     CDS             9679..10872
                     /gene="trpB"
                     /locus_tag="ROH59_004324"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HDX4806730.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETDVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            10872..11678
                     /gene="trpA"
                     /locus_tag="ROH59_004325"
     CDS             10872..11678
                     /gene="trpA"
                     /locus_tag="ROH59_004325"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HDX4806731.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPVGLLMY
                     ANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKAFVQPMKATTRR"
     gene            complement(11729..11869)
                     /locus_tag="ROH59_004326"
                     /pseudo
     CDS             complement(11729..11869)
                     /locus_tag="ROH59_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309783.1"
                     /note="receptor for colicin S4; incomplete; partial in the
                     middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
     gene            12054..12329
                     /locus_tag="ROH59_004327"
     CDS             12054..12329
                     /locus_tag="ROH59_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HDX4806732.1"
                     /translation="MTVFVLRGYIPHTTAKSVVGIGVSDNITTHSRVCGFFCVKHCHI
                     RIMVGRAGAEKSAPGFVMTGYANPVRLTTSLIGVRGGDHPINWSHHI"
     gene            12326..12883
                     /locus_tag="ROH59_004328"
     CDS             12326..12883
                     /locus_tag="ROH59_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDX4806733.1"
                     /translation="MNTAITFSNESPKVFFKDGRLVTTSQAVADYFDKQHKHVLAKID
                     TLDCSPEFTSANFSADVQTVEIGNGAERESRCYLITKDGFMFLVMGFTGKKAARLKEA
                     YIEKFNAMEEELHKRPPAAQNSPAPNNGCALLIHFDKHGQVEFTEKVPADAMVCTLER
                     FKFYLEQHGWIVARKEQLVERLMRF"
     gene            complement(13010..13180)
                     /locus_tag="ROH59_004329"
     CDS             complement(13010..13180)
                     /locus_tag="ROH59_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001710241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806734.1"
                     /translation="MVRLPPVVMSAKSATARTTIAREDAEDHQVKLSAQKLEELLASM
                     VKDEVDRNDGIY"
     gene            complement(13295..13564)
                     /locus_tag="ROH59_004330"
     CDS             complement(13295..13564)
                     /locus_tag="ROH59_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX4806735.1"
                     /translation="MLPQHSDIEIAWYASIQQEPNGWKTVTTQFYIQEFSEYIAPLQD
                     AVDLEIATEEERSLLEAWNKYRVLLNRVDTSTAPDIEWPANPVRE"
     gene            13621..>13946
                     /locus_tag="ROH59_004331"
     CDS             13621..>13946
                     /locus_tag="ROH59_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDX4806736.1"
                     /translation="MVKSMKKNTDDGAKIYTPLTLKLYDWWVLGVSNRLAWGCPTKEH
                     LLPHFLEHVGNNHLDIGVGTGFYLTHVPESSLISLMDLNEASLNAASTRAGESKIKHK
                     ISHDVF"
BASE COUNT         3502 a         3623 c         3432 g         3389 t
ORIGIN      
        1 atccggatta gtcgcataaa aattaacaag aaagttttca cgagaagcat agtattgttt
       61 aaagaaactt gcattcgccg caaccgcctt gttacccgca gtaataacag tttcagcttg
      121 ttcattcttc aatgcttcgg ttgcacaacc tgaaagcatt aacagcgata gaaatattcc
      181 actatatcta atcataaccc acctcttgac gttgagttta tctcagataa ttaaatagta
      241 atgtggctat tccctggcat tattcataag caagtatgaa attaaattaa aatactgcga
      301 ctatttatca tacttcaaat gaagaaaagg ccccgcaggg cctttattta atacttaact
      361 taaattaacc gttattatta cgtccgccag aacgacgacc gccgctcacc tgactgtgac
      421 gtttcaccgc acgacgaatc tgattcgcct tcatacgacg acggtctttt tctacagcga
      481 ctttagagct ggtttctggc ggtagttcca ccagttcgcg cagatagtta gtctgggcga
      541 ggtccagctc cgtccagcca ccgcgtggca gaccttttgg cagtgggata tcaccgtaac
      601 gaacgcgaat caggcggctc acctgcacac caaccgcttc ccacagacga cgaacttcac
      661 ggttacggcc ttcggtcaga gtaacgttgt accactggtt gatcccttcg ccgccgctga
      721 acttgatggt tttaaaggct gccggaccat cttccagctg cacgccacga ctcaaatcac
      781 gcagtttcgc gtcgtcaacc tgaccaaata cacgcacggc atattcacgt tcaacttcac
      841 ggcttggatg cattaaacgg tttgccagtt caccgtcggt ggtgaacaac aacagaccac
      901 aggtgttaac gtccagacga cctacggcaa tccagcgtgc gccacgcagc tttggcagac
      961 ggtcaaacac cgttggacgc ccttccggat cgttacgggt acacaactca ccttccggtt
     1021 tgtaataggc cagaacgcga caaatttgtt cagcggactc acgtaccgaa atcaggtgac
     1081 catcgatacg gattttcagt ccaggggtaa tttcaacgcg atcgccgagt ttagcaattt
     1141 tgccatcaac actcacacga ccggcttcaa taatagattc gatttcacgg cgagaaccgt
     1201 ggccggcacg cgccagcact ttctgtagct tttcgctcat agagcttcct tttggtgtcg
     1261 ccttcccagg cgtctgatat gcttttgtgc aacaatgagt cagaacttac atctgactca
     1321 ctgatagtaa agtctgtttg aactcttcag gccttaagta aacgactcga cgttttaact
     1381 ggcctggctt tgaggcgcaa catactacac tatctttatg gttaaagctt gtttcgatta
     1441 acatcagctt tattaccagc caccaccgcc tccgccaccc gcaccgccgc cagcaccacc
     1501 accggaataa cttcgcccca acaaactggt attggccccc agactcagat gcatctgtaa
     1561 tgagaacaaa acgccactac gggcaatttc cggggcgcgg acagccgctg tgagtgatgg
     1621 ggtgatacgt gcagcccatt ctctgccaag gtttgccgag accgcccaac ctaacaaagc
     1681 gtaatccagt ttccgtgctt cccctttcct ccgccgccca ctgtgtgttg ctgcctcttt
     1741 acgcgcaaga tagttaacga tagcttcacc gtgggcataa cgttgctgcc cagtttgggt
     1801 aaactttggc agaaaaatat accccatgcc agtgagataa ccggtcagga aaacagcgct
     1861 aaaataaccc gctggcatat accagtaaaa gaatacatct ccgacattga tgtagagaga
     1921 atagaaggcc acgcctgaac aaatcagtgg taaaaacaaa gtgatgatta cacgattaac
     1981 gcaaggcttg tcatcatcgc gggcaaacaa aagctcaagg gaacaaaata agaaaggaag
     2041 aagccagcag atcataataa acatatcgcc taccagactc attcctgccc aacctacggg
     2101 actcaggtta ccgtagagaa tgaccgccaa tatcgccatc ccgccccatt gcaaaaacgc
     2161 atcaggtcgg taaaacgaag actttttacg cggcagataa aatttctgca tccgtaaaaa
     2221 tgccttgcgt aagactctgt tgcgtctccc cgtaagaacg accttatcgc ctttacgaaa
     2281 taacgcttcc agtaataact gctctgcggg cagtaatacc gcattatttc tggtcgcgcc
     2341 ttcattaaca cgaatcagga tttgctggtt cttgtcataa tgagcttcca gatgaatttt
     2401 tcctttcaca atcagattta cgatatcggc gcaaaaacct ttatcgtcat aaaccagctt
     2461 cgcatcgaga cgtaacatgc cgggcgtgta atctggcgga atgacatcgg tttcaatcac
     2521 atctaccggc gtaaattgcg gcctgcgctt ccagagatat aaccatccac acgccaggaa
     2581 caggcacgga aaccaaatta acaacgatga cgtagagggt aaaagaagat ggctgaaaat
     2641 attcgtcgtt tgtggtgccg gggcattacc aagtaaagcg tgaggccagc ggtagaggac
     2701 cgtgaaatct tcacgataaa acggatcgcg agattcaatt cttccgtcct caaggatgcg
     2761 gccatttcga tatgtgtcgc cctcatctcc ggtaaagaga tcgatttcgc taaatggatt
     2821 acccgcaata tcaggcaact tgagtgaaaa tagggtctta tatatttcaa acggccagtg
     2881 gttaccggtc acgttccaga ttagcagatc agaatccccc tcacgcagga aagcattttt
     2941 aacctgataa tgaatttgat aatgatagtc gccttgaggc aagaaacgtt gtttatcgcc
     3001 cacgacaata ctcattaacc cgatatgcca gtcaagatgc cagggttcag aaataccatc
     3061 acgggtgacg ccaacaatat gatagttcag cagtgcagcg tccccatcag gctgcatcca
     3121 gagtcgcggt aaatcacgat aaaatccgtg cttaatctgc tgatttcgcg cctgaaaatg
     3181 aatgttctct ttgatgtcga gcaccccatt cggttgcaga gtggcttcaa catcaaagag
     3241 cgagatccct tcttcataag aagggatctc cgtgtttttc gcataactca acgaagagaa
     3301 aaaaagccca actatcaata gcaaaatgca gcgatatatc cctgccataa tcttccatcc
     3361 gtggaacgca atttgttata agaaaggctt cacatcacct acgccttcac gcaccacgac
     3421 cggcgtatca tcggtgagat caataaccgt tgttggtttc tgcccgagat agccgccgtg
     3481 aataatcaaa tccacctgtt tttccagacg gtctttaatt tcttccggat cggattcggt
     3541 aaattcactg cctggcagca ttagcgaagt ggaaagcatc ggttcgccca atgcttcaag
     3601 cagcgcctgc gcaatcgggt tagacggcac gcgcataccg atggttttgc gtttttcctg
     3661 caacagacgg cgtggcacct ccttagtccc cttcaggatg aaggtatagt tgcctggcgt
     3721 gttgtttttc atcaaacgaa acgcaacgtt atcgacaaat gaataggtcg agagttcaga
     3781 aagatcgcga cacatcaggg taaagttgtg accgtccggc agctggcgaa tacgacaaat
     3841 acgctccatc gcgtttttat cttcaatttt acagccgagc gcatagccgg aatcagttgg
     3901 ataaacaatc accccgcctt tacgcacgat ctccaccgcc tggttgatca ggcgttgctg
     3961 cgggttatca ggatgaatat aaaaaaactg gctcataatt ccctctctgt ggtgttctgc
     4021 ggctgttccc atagctgcca gacgccttca acgcctgcgg gcagccagag tttacgaccc
     4081 agttcgatcc acgggcatgg ttgatgaaaa tcagatcctt gtgatgccca taaatgatgc
     4141 tgacgcgcaa gtgtcgccag ctgggtgcgt tcattgggcg attgctggca ctgcgcgact
     4201 tccatcgcgt cgccgtggtg ttcggcaaaa tgcgcaacca atcttttcag ccatttagca
     4261 ctaagattgt accgccctgg atgagctagc accgccttac cgccagaatg atgaatgaca
     4321 tcaatagctt gttctattgt acaccactgt ggcggaacgt atccggtttt cccgcgcgcc
     4381 agatactttt taaagacatc cgccattgaa ctggcttttc cgcactccac aaggaaacgc
     4441 gcaaaatgac cgcgcgtcac cgcaccgccc tgcgccagtt gttgcgcgcc ttccagtgcc
     4501 ccaggtattt gtgctttttc aagtctttcg gcaatcagct gcgcccgctg attgcgccgt
     4561 tctgtctgct gcgcgaggaa ctcacacatt agcggatgag taatatcaat attcagcccg
     4621 acaatatgaa tttcatgatt ttcccagacc gtggaaattt ccacaccagg aataagattc
     4681 agcgccagtc ccgaacgtga aatttcctct cttgctggtg caattgcagc tgtggtgtca
     4741 tggtcggtga tcgccagggt gccgacgcgc atctcgactg cacggtgcac caatgcttct
     4801 ggcgtcaggc agccatcgga agctgtggta tggctgtgca ggtcgtaaat cactgagtaa
     4861 ttcgtgtcgc tcaaggcgca ctcccgttct ggataatgtt ttttgcgccg acatcataac
     4921 ggttctggca aatattctga aatgagctgt tgacaattaa tcatcgaact agttaactag
     4981 tacgcaagtt cacgtaaaaa gggtatcgac aatgaaagca attttcgtac tgaaaggttg
     5041 gtggcgcact tcctgaaacg ggcagtgtat tcaccatgcg taaagcaatc agatacccag
     5101 cccgcctaat gagcgggctt ttttttgaac aaaattagag aataacaatg caaacacaaa
     5161 aaccgactct cgaactgcta acctgcgtag gcgcttatcg cgacaaccca accgcgcttt
     5221 ttcaccagtt gtgtggggat cgtccggcaa cgctgctgct ggaatccgca gatatcgaca
     5281 gcaaagatga tttaaaaagc ctgctactgg tagacagtgc gctgcgcatt acagcattag
     5341 gtgacaccgt cacaatccag gcactttccg gcaatggcga agccctgctg gcactactgg
     5401 ataacgccct gcctgcgggt gtggaaaatg aacaatcacc aaactgccgc gtactgcgct
     5461 tcccgcctgt cagtccactg ctggatgaag acgcccgctt atgctccctt tcggtttttg
     5521 acgcattccg cttattacag aatctgttga atgtaccgaa ggaagaacga gaagcaatgt
     5581 tcttcggcgg cctgttctct tatgaccttg tggcgggatt tgaagattta ccgcaactgt
     5641 cagcggaaaa taactgccct gatttctgtt tttatctcgc tgaaacgctg atggtgattg
     5701 accatcagaa aaaaagcacc cgtattcagg ccagcctgtt tgctccgaat gaagaagaaa
     5761 aacaacgtct cactgctcgc cttaacgaac tacgtcagca actgaccgaa gccgcgccgc
     5821 cgctgccggt ggtttccgtg ccgcatatgc gttgtgaatg taaccagagc gatgaagagt
     5881 tcggtggcgt agtgcgtttg ttgcaaaaag cgattcgcgc cggagaaatt ttccaggtgg
     5941 tgccatctcg ccgtttctct ctgccctgcc cgtcaccgct ggcggcctat tacgtgctga
     6001 aaaagagtaa tcccagcccg tacatgtttt ttatgcagga taatgatttc accctgtttg
     6061 gcgcgtcgcc ggaaagttcg ctcaagtatg acgccaccag ccgccagatt gagatttacc
     6121 cgattgccgg aacacgtcca cgcggtcgtc gtgccgatgg ttcactggat agagacctcg
     6181 acagccgcat cgaactggag atgcgtaccg atcataaaga gctttctgaa catctgatgc
     6241 tggtggatct cgcccgtaat gacctggcgc gtatttgcac ccccggcagc cgctacgtcg
     6301 ccgatctcac caaagttgac cgttactctt acgtgatgca cctggtctcc cgcgttgttg
     6361 gtgagctgcg ccacgatctc gacgccctgc acgcttaccg cgcctgtatg aatatgggga
     6421 cgttaagcgg tgcgccgaaa gtacgcgcta tgcagttaat tgccgaagca gaaggtcgtc
     6481 gccgcggcag ctacggcggc gcggtaggtt attttaccgc gcatggcgat ctcgacacct
     6541 gcattgtgat ccgctcggcg ctggtagaga acggagtcgc caccgtgcaa gccggtgctg
     6601 gcgtggtact tgattctgtt ccgcagtcgg aagccgacga aacccgtaat aaagcccgcg
     6661 ctgtactgcg cgctattgcc accgcgcatc atgcacagga gacgttctaa tggctgacat
     6721 tctgctgctc gataatatcg actcttttac ttacaacctg gcagatcagt tgcgcagcaa
     6781 tggtcataac gtggtgattt accgcaacca tattccggcg cagaccttaa ttgaacgcct
     6841 ggcgacgatg agcaatccgg tgctgatgct ttctcctggc cccggtgtgc cgagcgaagc
     6901 cggttgtatg ccggaactcc tcacccgctt gcgtggcaag ctgccaatta ttggcatttg
     6961 cctcggacat caggcgattg tcgaagctta cgggggctat gtcggtcagg cgggcgaaat
     7021 tcttcacggt aaagcgtcga gcattgaaca tgacggtcag gcgatgtttg ccggattaac
     7081 aaacccgctg ccagtggcgc gttatcactc gctggttggc agtaatattc cggccggttt
     7141 aaccatcaac gcccatttta atggcatggt gatggcggtg cgccacgatg cggatcgcgt
     7201 ttgtggattc cagttccatc cggaatccat tcttactacc cagggcgctc gcctgctgga
     7261 acaaacgctg gcctgggcgc agcagaaact agagcaaacc aacacgctgc aaccgattct
     7321 ggaaaaactg tatcaggcac agacgcttag ccaacaagaa agccaccagc tgttttcagc
     7381 ggtggtacgt ggcgagctga agccggaaca actggcggcg gcgctggtga gcatgaaaat
     7441 tcgcggtgag cacccgaacg agatcgccgg ggcagcaacc gcgctactgg aaaacgccgc
     7501 gccgttcccg cgcccggatt atctgtttgc cgatatcgtc ggtactggcg gtgacggcag
     7561 caacagcatc aatatttcta ccgccagtgc gtttgtcgcc gcggcctgcg ggctgaaagt
     7621 ggcgaaacac ggcaaccgtt gcgtctccag taaatccggc tcgtcggatc tgctggcggc
     7681 gttcggtatt aatcttgata tgaacgccga taaatcgcgc caggcgctgg atgaattagg
     7741 cgtctgtttc ctctttgcac cgaaatatca caccggattc cgccatgcaa tgccggttcg
     7801 ccagcaactg aaaacccgca cactgttcaa tgtgctgggg ccattaatta acccggcgca
     7861 tcctccgctg gcgttaattg gtgtctacag cccggagctg gtgctgccga ttgccgaaac
     7921 cttgcgcgtg ctggggtatc aacgcgcggc agtggtgcac agcggcggga tggatgaagt
     7981 ttcattacac gcgccgacaa tcgttgccga actgcatgac ggcgaaatta agagctatca
     8041 attgaccgct gaagattttg gcctgacacc ctaccaccag gagcaactgg caggcggaac
     8101 accggaagaa aaccgtgaca ttttaacacg cttgttacaa ggtaaaggcg acgccgctca
     8161 cgaagcagcc gtcgcggcga atgtcgccat gttaatgcgc ctgcatggcc atgaagatct
     8221 gcaagccaat gcgcaaaccg ttcttgaggt actgcgcagt ggttccgctt acgacagagt
     8281 caccgcactg gcggcacgag ggtaaataat gcaaaccgtt ttagcgaaaa tcgtcgcaga
     8341 caaggcgatt tgggtagaag cccgcaaaca gcagcaaccg ctggccagtt ttcagaatga
     8401 gattcagccg agcacgcgac atttttatga tgcgctacag ggtgcacgca cggcgtttat
     8461 tctggagtgc aaaaaagcgt cgccgtcaaa aggcgtgatc cgtgatgatt tcgatccggc
     8521 acgcattgct gccatttata aacattacgc ttcggcaatt tcagtgctga ctgatgagaa
     8581 atattttcag gggagctttg atttcctccc catcgtcagc caaatcgccc cgcagccgat
     8641 tttatgtaaa gacttcatta tcgatcctta ccagatctat ctggcgcgct attaccaggc
     8701 cgatgcctgc ttattaatgc tttcagtact ggatgacgaa caatatcgcc agcttgcagc
     8761 cgtcgcccac agtctggaga tgggtgtgct gaccgaagtc agtaatgaag aggaactgga
     8821 gcgcgccatt gcattggggg caaaggtcgt tggcatcaac aaccgcgatc tgcgcgattt
     8881 gtcgattgat ctcaaccgta cccgcgagct tgcaccgaaa ctggggcaca acgtgacggt
     8941 aatcagcgaa tccggcatca atacttacgc tcaggtgcgc gagttaagcc acttcgctaa
     9001 cggctttctg attggttcgg cgttgatggc ccatgacgat ttgaacgccg ctgtgcgtcg
     9061 ggtgttgctg ggtgagaata aagtatgtgg cctgacacgt gggcaagatg ctaaagcagc
     9121 ttatgacgcg ggcgcgattt acggtgggtt gatttttgtt gcgacatcac cgcgttgcgt
     9181 caacgttgaa caggcgcagg aagtgatggc tgcggcaccg ttgcagtatg ttggcgtgtt
     9241 ccgcaatcac gatattgccg atgtggtgga caaagctaag gtgttatcgc tggcggcagt
     9301 gcaactgcat ggtaatgaag atcagctgta tatcgacact ctgcgtgagg ctctgccagc
     9361 acacgtcgcc atctggaagg ctttaagtgt cggtgaaact cttcccgcgc gcgattttca
     9421 gcacatcgat aaatatgtat tcgacaacgg tcagggcggg agcggacaac gtttcgactg
     9481 gtcactatta aatggtcaat cgcttggcaa cgttctgctg gcggggggct taggcgcaga
     9541 taactgcgtg gaagcggcac aaaccggctg cgccgggctt gattttaatt ctgctgtaga
     9601 gtcgcaaccg ggtatcaaag acgcacgtct tttggcctcg gttttccaga cgctgcgcgc
     9661 atattaagga aaggaacaat gacaacatta cttaacccct attttggtga gtttggcggc
     9721 atgtacgtgc cacaaatcct gatgcccgct ctgcgccagc tggaagaagc ttttgtcagc
     9781 gcgcaaaaag atcctgaatt tcaggctcag ttcaacgacc tgctgaaaaa ctatgccggg
     9841 cgtccaaccg cgctgaccaa atgccagaac attacagccg ggacgaacac cacgctgtat
     9901 ctgaagcgcg aagatttgct gcacggcggc gcgcataaaa ctaaccaggt actcggtcag
     9961 gctttactgg cgaagcggat gggtaaaact gaaattattg ccgaaaccgg tgccggtcag
    10021 catggcgtgg cgtcggccct tgccagcgcc ctgctcggcc tgaaatgccg tatttatatg
    10081 ggtgccaaag acgttgaacg ccagtcgcct aacgttttcc ggatgcgctt aatgggtgcg
    10141 gaagtgatcc cggtgcatag cggttccgcg accctgaaag atgcctgtaa tgaggcgcta
    10201 cgcgactggt ccggcagtta tgaaaccgcg cactatatgc tgggtaccgc agctggcccg
    10261 catccttacc cgaccattgt gcgtgagttt cagcggatga ttggcgaaga aacgaaagcg
    10321 cagattctgg aaagagaagg tcgcctgccg gatgccgtta tcgcctgtgt tggcggtggt
    10381 tcgaatgcca tcggtatgtt tgcagatttc atcaacgaaa ccgacgtcgg cctgattggt
    10441 gtggagcctg gcggtcacgg tatcgaaact ggcgagcacg gcgcaccgtt aaaacatggt
    10501 cgcgtgggca tctatttcgg tatgaaagcg ccgatgatgc aaaccgaaga cgggcaaatt
    10561 gaagagtctt actccatttc tgccgggctg gatttcccgt ccgtcggccc gcaacatgcg
    10621 tatctcaaca gcactggacg cgctgattac gtgtctatta ccgacgatga agccctggaa
    10681 gcctttaaaa cgctttgcct gcatgaaggg atcatcccgg cgctggaatc ctcccacgcc
    10741 ctggcccatg cgctgaaaat gatgcgcgaa aatccggaaa aagagcagct actggtggtt
    10801 aacctttccg gtcgcggcga taaagacatc ttcaccgttc acgatatttt gaaagcacga
    10861 ggggaaatct gatggaacgc tacgaatctc tgtttgccca gttgaaggag cgcaaagaag
    10921 gcgcattcgt tcctttcgtc accctcggtg atccgggcat tgagcagtcg ctgaaaatta
    10981 tcgatacgct aattgaagcc ggtgctgacg cgctggagtt aggcatcccc ttctccgacc
    11041 cactggcgga tggcccgacg attcaaaacg ccacactgcg tgcctttgcg gcgggtgtga
    11101 ccccggcgca gtgctttgag atgctggcac tgattcgtca aaaacatccg accattcctg
    11161 ttggcctgct gatgtacgcc aacctggtgt ttaacaaagg cattgatgag ttttacgccc
    11221 agtgcgagaa agtcggcgtc gattcggtgc tggttgccga tgtgccagtt gaagagtccg
    11281 cgcccttccg ccaggccgcg ttgcgtcata atgtcgcacc tatctttatt tgcccgccga
    11341 atgccgacga tgatttgctg cgccagatag cctcctacgg tcgtggatac acctatttat
    11401 tgtcacgtgc gggcgtgacc ggcgcagaaa accgcgccgc gttacccctc aatcatctgg
    11461 ttgcgaagct gaaagagtac aacgctgcac ctccattgca gggatttggt atttccgccc
    11521 ctgatcaggt aaaagcagcg attgatgcag gagctgcggg cgcgatttct ggttcggcca
    11581 tcgttaaaat catcgagcaa catattaatg agccagagaa aatgctggcg gcactgaaag
    11641 cttttgtaca accgatgaaa gccactacac gacgttaatt tgagacaaac cgccagaaaa
    11701 catctggcgg tttattgatg gtaaaaaatt agaagcggta acctgcagag aacataaata
    11761 cccacgggtc aaggcgtacg ttgtcagaat aacgccctgc aggcagcact gcgccgttgg
    11821 atttatattt cacttcggta tcgatatcca tgtaccagac cgacatgttt taaaaaatgc
    11881 aataagacat tgtatctgaa agaaaaaaca ggatttgagg cgctttttta taccgttttt
    11941 ccgtgttttt aactgcctga ttttattgaa atctttttta gttttgcaga aaggattttt
    12001 tgctcgatcg ctttaatttt atacattcct gataacggaa atttttttgc ccgttgacag
    12061 tttttgttct ccggggctat attcctcaca caaccgcaaa atcggttgtc gggattggcg
    12121 tctcggataa catcacaacg catagccgcg tttgcggttt tttttgcgtt aagcattgcc
    12181 acattcgcat tatggtgggg cgtgcagggg cggagaaatc cgcgccgggt tttgtgatga
    12241 ccggttacgc caaccctgta cgtctcacca cctccctgat tggcgtcaga ggtggtgatc
    12301 atccaattaa ttggagtcat cacatatgaa tacagctata actttttcta acgagtcacc
    12361 aaaagtcttt ttcaaagatg gtcgcctggt taccacctct caagctgttg ccgactactt
    12421 cgataaacaa cataaacacg ttttagctaa gattgacaca ctcgactgct ctcccgaatt
    12481 tacatcagcc aacttttcgg ccgatgttca gactgtcgaa attggcaacg gcgcagaacg
    12541 tgaatcacga tgctacctga tcacaaaaga cggcttcatg ttcctcgtaa tgggatttac
    12601 tggcaaaaaa gcagccagac taaaagaagc ttacattgaa aaatttaacg caatggaaga
    12661 agaactccac aaacgtcctc ctgcagcaca aaactccccc gccccaaata atggatgcgc
    12721 attactgatc cacttcgata aacacggtca ggtcgagttc acagaaaaag tccccgccga
    12781 tgcgatggta tgcacgctgg aacggtttaa attttatctg gagcaacatg ggtggatcgt
    12841 tgcccgtaaa gaacaattgg tggaaaggtt gatgcggttt taatgaatgc aaaaccccgg
    12901 atgatcaccg gggttaattt tatcgagcgt gattgccgct aatcgccatc gctctgattg
    12961 agcgtaaatc attcaggtta ttcagttctt ccttctgctc tcgctgacgt caataaatcc
    13021 catcattgcg atcaacctca tccttaacca ttgatgcgag cagttcttcc agtttctgcg
    13081 ctgacagctt tacctggtga tcttcagcat cttcccgggc tattgtggtt cgcgcagtgg
    13141 ctgattttgc tgacatcacc acagggggca gacggaccat tgaaccatgg cctccggaac
    13201 aaataagggc aaaaataaca accactatcg aaagctcaca aactaaccgc agcacgttcc
    13261 tgcatacgac gtgtctgcgg cataatccca atgattactc cctgacagga tttgcaggcc
    13321 actcaatatc aggtgcagtt gatgtatcaa cacgattcaa caatacccga tatttattcc
    13381 atgcctccag caacgatctt tcttcctccg ttgcgatttc cagatctaca gcatcctgca
    13441 gtggcgcaat atactcactg aattcctgga tgtagaactg tgtggtgacg gtcttccagc
    13501 cattcggctc ctgctgtatc gaagcatacc aggctatttc aatatcgcta tgctgcggca
    13561 gcatttaacc ccttgtaatt catcgccata attgatttaa ttcacaaata aaactataac
    13621 atggtgaaat caatgaaaaa aaacacagat gatggggcta aaatttacac accacttacc
    13681 ctaaagcttt atgactggtg ggttttggga gtatcaaatc ggcttgcatg gggatgtcct
    13741 acaaaggaac accttcttcc acactttctg gaacatgtag gtaacaacca tctggatatt
    13801 ggtgttggaa ctgggtttta ccttactcac gtacctgaga gtagtctgat atctttaatg
    13861 gatttgaacg aagctagcct gaacgcggca tctacaaggg ctggggaatc aaaaattaaa
    13921 cataaaatta gccatgatgt ttttga
//
LOCUS       DAPOXO010000110        13806 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.110, whole genome shotgun sequence.
ACCESSION   DAPOXO010000110 DAPOXO010000000
VERSION     DAPOXO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13806
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.110"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(93..866)
                     /locus_tag="ROH59_004332"
     CDS             complement(93..866)
                     /locus_tag="ROH59_004332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HDX4806737.1"
                     /translation="MIKHTLLVPFFFSALPAYAGLTSITAGYDFTDYSGEHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVNAWQGGVSLYTGPVITSYRYTH
                     YDSSDAGSSYSNMISVRLKDPRGAGYTQLWLSRGTGAYTYDWTPETRYGSMKSISLQR
                     IQPLTEQLNLGLTAGKVWFNTPTDDYNGLQLAAHLIWKF"
     gene            complement(868..1392)
                     /locus_tag="ROH59_004333"
     CDS             complement(868..1392)
                     /locus_tag="ROH59_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDX4806738.1"
                     /translation="MIIDESAGEVVIGANTRICHGAVIQGPVVIGANCLIGNYAFIRP
                     GTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVANQAYLGAQVRTSNHRLDEQ
                     PVSVRTPEGIIATGCDKLGCYIGKRSRLGVQVIILPGRIISPNTQLGPRVIVERNLPS
                     GTYSLRQELIRTGD"
     gene            complement(1427..2623)
                     /locus_tag="ROH59_004334"
     CDS             complement(1427..2623)
                     /locus_tag="ROH59_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX4806739.1"
                     /translation="MKTLLFIFMTIAMLLWFLSTLRRKPCQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     HGLKYATCDQVFLSDADTFVPPDNDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQFLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVLYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWVGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGT
                     EKLSEA"
     gene            complement(2637..3299)
                     /locus_tag="ROH59_004335"
     CDS             complement(2637..3299)
                     /locus_tag="ROH59_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDX4806740.1"
                     /translation="MDYMLNSTTSSGKRTGILAIGAHPDDIELGCGASLSYYSNEKVY
                     IISVVMTPGCCGAEYIDRHKESQEALNMLGCNKLIPLNFEDTRLYLQIKEMISSLEYI
                     IENETPQDVEITRVYTMNNTDRHQDHIAVYQASMVACRYIPQILGYETPSTCLSFLPQ
                     VFESVDEVHFNKKILALQKHKSQIHRRYIQPEYIIAQAKFRGQQVSHSMCEGFVVHKM
                     VL"
     gene            4338..5561
                     /locus_tag="ROH59_004336"
     CDS             4338..5561
                     /locus_tag="ROH59_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDX4806741.1"
                     /translation="MGTIQKIRTDVNVLYAAIHRIEWLFETFSSVCLSFSGGKDSTVL
                     LHLTADVARRKKRRFSVLFIDWEAQYQCTIAHILKMREMYRDVTETFYWVALPLTTVN
                     GVSQFQPEWICWEPGVEWVRQPPDDAITDMSYFPFYRYAMTFEEFVPAFSSWFAGNRC
                     GVAILTGVRADESLNRFMGLVSQRKLRYADDKPWTTASPEGFYYTLYPLYDWKARDIW
                     IYNARTRAIYNPLYDLMYRAGVPLRNMRVCEPFGPEQRKGLWLYHVLEPETWARMCER
                     VSGAASGALYANESGAYFALRKRITKPPHHTWRSYAMFLLDVMPERTAEHYRNKIAVY
                     LRWYQTRGFPDDIPDEQENDLGSRDIPSWRRICKTLIKNDFWCRTLSFSPNKPRHYER
                     YLQRMKERRKEWGIL"
     gene            5546..6190
                     /locus_tag="ROH59_004337"
     CDS             5546..6190
                     /locus_tag="ROH59_004337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HDX4806742.1"
                     /translation="MGDSVTPEVEVLSNMIRQYFSQERSEEETIRALNHLRRVLHEVS
                     PFAQEPVDCVLWVKADEVVANDYNPNVMSSSEKKLLKHSLEQDGFTQPVVVSEEKEHY
                     LVVDGFHRQLLGRKADTRKRLKGWLPVTCINPERKGQASRIAATIRHNRARGKHQITS
                     MSDIVRDLSRLGWTDERIGTELGMDQDEVLRLKQISGLTELFQEENFSPSWTVR"
     gene            complement(6561..8708)
                     /locus_tag="ROH59_004338"
     CDS             complement(6561..8708)
                     /locus_tag="ROH59_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDX4806743.1"
                     /translation="MLYNIPCRIYILSTLSLCISGIVSTATATSSETKISNEETLVVT
                     TNRSASNLWESPATIQVIDQQTLQNSTNASIADNLQDIPGVEITDNSLAGRKQIRIRG
                     EASSRVLILIDGQEVTYQRAGDNYGVGLLIDESALERVEVVKGPYSVLYGSQAIGGIV
                     NFITKKGGDKLASGVVKAVYNSATAGWEESIAVQGSIGGFDYRINGSYSDQGNRDTPD
                     GRLPNTNYRNNSQGVWLGYNSGNHRFGLSLDRYRLATQTYYEDPDGSYEAFSVKIPKL
                     EREKVGVFYDTDVDGDYLKKIHFDAYEQTIQRQFANEVKTTQPVPSPMIQALTVHNKT
                     DTHDKQYTQAVTLQSHFSLPANNELVTGAQYKQDRVSQRSGGMTSSKSLTGFINKETR
                     TRSYYESEQSTVSLFAQNDWRFADHWTWTMGVRQYWLSSKLTRGDGVSYTAGIISDTS
                     LARESASDHEMVTSTSLRYSGFDNLELRAAFAQGYVFPTLSQLFMQTSAGGSVTYGNP
                     DLKAEHSNNFELGARYNGNQWLIDSAVYYSEAKDYIASLICDGSIVCNGNTNSSRSSY
                     YYYDNIDRAKTWGLEISAEYNGWVFSPYISGNLIRRQYETSTLKTTNTGEPAINGRIG
                     LKHTLVMGQANIISDVFIRAASSAKDDSNGTETNVPGWATLNFAVNTEFGNEDQYRIN
                     LALNNLTDKRYRTAHETIPAAGFNAAIGFVWNF"
     gene            10380..10925
                     /gene="cobU"
                     /locus_tag="ROH59_004339"
     CDS             10380..10925
                     /gene="cobU"
                     /locus_tag="ROH59_004339"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDX4806744.1"
                     /translation="MMILVTGGARSGKSRHAEVLIGDSSQVLYIATSQILDDEMAARI
                     EHHRQSRPEHWRTVERWQHLDELIHADINPNEAVLLECVTTMVTNLLFDYGGDKDPDE
                     WDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
     gene            10922..11665
                     /gene="cobS"
                     /locus_tag="ROH59_004340"
     CDS             10922..11665
                     /gene="cobS"
                     /locus_tag="ROH59_004340"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDX4806745.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLVFMVLQAWCGVPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIEFGELVFLLALL"
     gene            11677..12756
                     /gene="cobT"
                     /locus_tag="ROH59_004341"
     CDS             11677..12756
                     /gene="cobT"
                     /locus_tag="ROH59_004341"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDX4806746.1"
                     /translation="MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAI
                     QLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
                     RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVV
                     RRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGSGAALAMSIIEAACA
                     IYNNMGELAASNIVLPGNTTSDLNS"
     gene            12818..13753
                     /gene="ldtA"
                     /locus_tag="ROH59_004342"
     CDS             12818..13753
                     /gene="ldtA"
                     /locus_tag="ROH59_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDX4806747.1"
                     /translation="MMRRVNILCSFALLFASQNSLAVTYPLPPEGSRLVGQSLTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKPGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGKLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSKWLEVHEPLSRNRAEYESDRKVPLPVTPSLR
                     AFINGQEVDVNRANAALQHRSGMPVQISSGSRQMF"
BASE COUNT         3683 a         2927 c         3314 g         3882 t
ORIGIN      
        1 attgcccgaa attaattata ttgtttatta tcaaaccgag ttatagcttt tctctgaaaa
       61 ctaccgaata aaatatactg atagactgct gcctagaatt tccagatcag gtgggctgca
      121 agttgcagac cgttataatc atcggttggg gtgttgaacc acactttacc tgccgtcaac
      181 ccgagattaa gttgctcagt cagcggttga attcgttgca aactgatgct cttcatgctg
      241 ccgtagcgtg tttctggcgt ccagtcgtag gtgtaagcac ctgttccgcg gcttagccat
      301 agttgcgtat aaccagcacc gcgcgggtcc ttcagacgca cggaaatcat attgctataa
      361 ctactacctg catcgctgga gtcataatgg gtatagcggt aactggtgat caccgggcca
      421 gtatagagtg atacgccgcc ttgccaggca ttgacttcga catcatcgta atatttagtg
      481 tagcgataac cggtcgtgaa aagcgttttt ggcaacaggg ctaggttaat atcctgtcga
      541 aaatcctggc gggcaaagac cggcgtatta tccgcaaagg caatacccgt tcgggttgtc
      601 agccagttat tccatttgta ccagactgca ccctggccgc gagtggcatt gaaatgttca
      661 gtttcataat cacgacgccc ctgggaaaga ttaaaaagca gcgttgcgtt ttcaactttt
      721 gctaccagtt cagcatacgc taaattacgg ttgccatgtt cgccagaata atcggtaaaa
      781 tcgtagcccg cggtaatgga agttaacccg gcataagcgg gcaatgcact aaaaaaaaac
      841 ggcactaata acgtatgctt tatcatttta atctcctgta cggataagtt cttgtcggag
      901 tgagtaagtt ccactaggta aattacgttc tacaatcacg cgcgggccaa gttgtgtgtt
      961 cggagaaata attcgcccag gcaaaataat aacttgtacg ccaaggcgtg aacgcttccc
     1021 gatataacaa cctaatttat cgcatccggt agcgataatt ccctctggag ttcgaacaga
     1081 cacgggttgt tcatccagac gatgattact ggtacgtact tgtgcgccca aatatgcctg
     1141 gtttgcaact accgagtcgg caataaagca ttgcggacca atcgttgctt ccgcttcaat
     1201 aaccgcattt ttaatttcgg tggcaaaacc aatttttacg ccattgctga ttattgtgcc
     1261 aggacgaata aacgcataat tacctatcag gcagtttgcg ccaatcacta ccggcccctg
     1321 aataacggca ccgtggcaaa tacgggtatt cgcgccgata acaacctcac cggcactttc
     1381 atcaataatc acctggtctg caatctgaac atttttctct ttagcattaa gcttcagata
     1441 gtttttcagt tcctgtgaca gaaggttggg aataagcggt tgacgcttcc accagtgcgg
     1501 aatagcgggt gggtttgtcg cgctgaggtt cgcgtccagt aaaaaaggca ataagtccat
     1561 aaataatcca gatggcataa gctaataata catacacaac ggaaagcggt gctaaaggca
     1621 ccaacaacca gcaacgatga aaccaggcgc taaatgcacc aataacacaa actacgccga
     1681 cccagataag cgggaacatt gccaacacca caccatgtgg cccggtggtg atgaattcat
     1741 taaaccaggt agtgagataa ataccaacgc cataaagcac aaccaacagc ataggaaata
     1801 tactgaagat accgaagcgg ctaaataaaa gtcttttatg caggcgcata cagaccgcgt
     1861 agcccacaat ccaacgccgc cagcggcgcc actcctcacg cggactgtta cattcctgtg
     1921 ggtatacgat gcagcgattc gcctgccgaa tacggtagcc gtttgccacc aacgtccagg
     1981 tgagatcaag gtcttcgact ttagtacgat cagagaaacc gaacttacgc aatacatcag
     2041 tacggaacat cccgcaggca ccgctgataa taaacggtgc accgcccaga aactgctgta
     2101 gcgtgcgctt cataacaatc atcggcaact ttacggtggc gcggatatgt ggcagcagac
     2161 ctgccccttt taacgcggtg gagggaattc cgccaacggc atcagcgccg cgctcaattt
     2221 ctgccagcat atagcccatt ccatcattat caggtggaac gaaagtatct gcatcactta
     2281 aaaatacttg atcacacgtg gcgtatttta gtccatgcat tagtgcgcca cctttaccgg
     2341 tgtttttttg cgtgacggca acaaagcggt cgccccattt gcgtttgact tccgccatga
     2401 ccgcttcggt attgtccgtg gatccgtcgt taacgcaaat tacccggcaa aaataagggt
     2461 tacgcagcag attatccagt gactgcgcca gacacgggcc ttcgttataa gctggtataa
     2521 tggcgtcaat acagcctttc ttttgacagg gtttacgtct tagcgtactt aaaaaccata
     2581 gcaacattgc tatggtcatg aagataaata acaaagtttt catttctatt actccgttac
     2641 aacaccatct tatggacaac aaaaccttca cacatagaat gactaacctg ttgtcctcgg
     2701 aatttggctt gagcaattat gtattctggc tgtatgtatc ttcgatggat ctggctttta
     2761 tgcttttgta atgctaatat ttttttatta aaatggacct catctacaga ttcaaaaact
     2821 tgaggtaaaa atgacagaca tgtacttggt gtttcgtatc ctagtatttg aggaatataa
     2881 cgacaggcaa ccattgatgc ctgataaaca gcaatgtgat cctgatgcct gtcagtatta
     2941 ttcatggtgt aaactcgagt aatttccaca tcctggggcg tttcattctc aattatgtat
     3001 tccagagatg atatcatctc ttttatttgc aaatataatc tggtatcttc aaaatttaga
     3061 gggattagtt tattgcatcc taacatattt aatgcttctt gtgattcctt gtgacgatca
     3121 atatactctg cgccacagca accaggtgtc atgacaacag atataatata tactttttca
     3181 ttagaataat atgaaagaga tgcaccacat cctaattcta tatcatcagg atgggcacca
     3241 attgctaaaa tgccggttct ttttcccgaa gatgttgtag aattcaacat gtaatctatc
     3301 cttttagata tgccatatga atccccatca taaattatca ctatcataaa aattaatctt
     3361 attaaatata ctttatattt actttttcag aggcagagaa gcatcattta tgcaacaaga
     3421 agatcttcat ttctgttaaa aaaacagagt ttatatgcta ttacggattt cagtcgtagc
     3481 aagttgaact gtgatcgcat taagactaat cttctggctt gtaaaggcct tagttccgtc
     3541 atgactctcc catcaggcca tagttgagca aaatcctgaa agaattatca cctattgtat
     3601 cttcagatac gggagttttt gtccagtatt gttggaataa tcatgtgact atattgttct
     3661 tgtagttgga acgtcttata aataaaacga aaaggcagta agtttgttgt atttattgat
     3721 atttttcatt cagttagttg gcaataatca gttatggttg tattcaaaag tacagctaga
     3781 acgaaattaa aataacggga gcatcgtaca tgacttgata tttcagaggg ctaagtatta
     3841 atatattact acgatctgtc atcattgact atcaatatat tagttagtta aatatctctt
     3901 tgtgtcattc tggctagtat atactcatta tcatgaatgc tgccatgcat agctaggtca
     3961 tcaccaatta atgatattct ctggataatg attcaagagt ttaagttcat tgtatatata
     4021 agtttgtatt caaaggtaat aaattccttg tttattattt ctcatgaaaa tagttaagaa
     4081 ggagtgaaga gtctgttttt ttggtaggag agtctttatt tatgtgtttg ctattaatga
     4141 atttttgtta aggtagcctc atttgtcata attttgctaa tatatgtatc gtcatatgtc
     4201 gtgttttact aaaaacttaa ctatcatgaa ctcgtgatag taacaatata cccttaaggt
     4261 agaacttttt cttgatgaga aggtttaagt ttgtagttca gaatattact gccaagatag
     4321 tttatactag gatatgtatg ggaaccatac agaagataag aacagatgtt aatgtattat
     4381 atgcggccat tcaccgtatt gagtggttgt ttgagacatt ttcatctgtt tgtttgtctt
     4441 tttctggagg aaaagactct actgtgctgc tccatcttac ggccgatgtg gctcgcagga
     4501 agaaacgtcg tttctctgta ttattcattg actgggaagc tcagtaccag tgcacaattg
     4561 cacacattct gaagatgagg gagatgtatc gggatgtgac ggagactttt tactgggtgg
     4621 cactccccct gactacggta aacggtgtct ctcagtttca gccggaatgg atatgctggg
     4681 aaccaggtgt ggagtgggtt cgtcagccac cagatgacgc tattacagat atgtcgtatt
     4741 tcccatttta tcggtatgcc atgacgtttg aagaatttgt tccggcattt tcttcctggt
     4801 ttgccggtaa ccggtgtgga gtggcaatac tgactggtgt tcgtgctgat gaatcgctca
     4861 atcgctttat gggactggtg tctcagcgca aactgagata tgcagatgat aaaccctgga
     4921 ccacagcgtc acctgaaggg ttttattaca ccttgtatcc gttgtatgac tggaaagccc
     4981 gtgatatatg gatatataac gccagaaccc gagctatcta caatcccctg tatgacctga
     5041 tgtaccgtgc cggcgtgccg ttacgcaaca tgcgggtctg tgagcctttt ggcccggaac
     5101 agcgtaaggg actgtggctt taccatgttc tggagccgga aacttgggcc aggatgtgtg
     5161 agcgggtgtc gggtgctgcc agcggggcgc tttatgccaa tgagagcggt gcctattttg
     5221 ccctgcgtaa gcgtatcacg aagccacctc atcatacctg gcgtagctat gcgatgttcc
     5281 tgctggatgt gatgccggaa agaacggcag aacattaccg taataaaatt gctgtctacc
     5341 tgcgctggta tcagacgcgg ggcttcccgg atgacatccc ggatgaacag gagaatgacc
     5401 tggggagccg ggatatcccg tcttggcgac gtatctgtaa gacactcata aagaatgatt
     5461 tctggtgccg gaccctctcc ttcagtccga acaaaccccg gcactatgaa cgttatctgc
     5521 agcgtatgaa agaaaggagg aaggaatggg ggattctgtg acacctgagg tggaagtatt
     5581 gagcaacatg attcgacagt acttcagtca ggaacgatct gaagaagaga ccatacgagc
     5641 ccttaatcat ctgcgcaggg tgttgcatga ggtcagccct tttgcacagg agcctgtgga
     5701 ctgtgtgttg tgggtgaaag cggatgaggt ggtggccaac gattacaatc ccaatgtcat
     5761 gtcttccagt gaaaaaaaac tgcttaaaca ttcactggag caggatggat tcacgcagcc
     5821 tgtggtggtt tcggaagaga aggagcatta tctggtcgtg gatggttttc atcgtcagtt
     5881 gctgggcagg aaagcggata cgagaaaacg tctgaagggt tggctgccag tgacctgtat
     5941 taatccggaa agaaagggac aggcatcacg tattgccgca accatacggc ataaccgtgc
     6001 caggggaaaa caccagataa cgtcaatgtc tgacattgtc agggaccttt cgcgtctggg
     6061 ctggacagat gagcgtattg gcacagagtt gggcatggac caggatgaag tgctgaggct
     6121 gaaacagatt agcgggctga cagagctgtt tcaggaagag aatttcagcc cttcatggac
     6181 ggttcgttga tattgtaaaa tatgatagtt ggagtaaggg gcaatagaag gagaatattt
     6241 atcccacctt cttccgagtc gggataaatc aaaaggtatt atccattgat tcagtatctg
     6301 ggtgagagta aataatctaa aaatagtatt gcgttgtgaa ctgatatcac ttttgaatta
     6361 caaaggtata ggctcagtaa ccagctttat aagtcattgt cgtagcaatg actatagagt
     6421 catgctggcg ggaagaataa atattcaccc ccagatggaa aacaacgtcg aaaaaccttc
     6481 aacaaacaca atacgttcgt tagcctgccc gcaaagcggg cagatcagga caaagaattc
     6541 cataacgatt gtttttgtca tcagaaattc catacaaaac ctatagctgc attaaaacct
     6601 gctgcaggaa tagtttcatg tgctgtacgg tagcgtttgt ctgtcaggtt attgagtgct
     6661 aggttaatcc ggtactgatc ctcgttaccg aattctgtat ttactgcaaa gttgagagtg
     6721 gcccagcccg gaacatttgt ttcggtaccg ttactgtcat cttttgcact agaggcagca
     6781 cgaataaaaa catcagagat tatgttggcc tgacccatca caagagtatg tttcagccct
     6841 atacgtccgt ttatcgctgg ttctcctgta ttagttgttt ttaatgttga agtttcatat
     6901 tgccgacgaa ttaaattgcc actgatatat ggcgagaaaa cccagccatt atattccgcg
     6961 cttatttcca gtccccatgt ttttgcccga tcaatattgt cataataata gtagctacta
     7021 cgggaggagt tggtgttacc attgcaaact atactgccat cacagatcag acttgcaata
     7081 taatctttag cttctgagta gtaaactgcg ctgtcaatca gccactgatt accattatat
     7141 cgtgcaccta attcaaagtt attggagtgt tcagccttaa gatcaggatt tccgtatgtg
     7201 acactgccgc ccgcagatgt ctgcataaaa agctgggaga gtgtgggaaa tacgtagcct
     7261 tgcgcgaacg cagcgcgtaa ctccaagtta tcgaaacctg aatagcgcag gcttgtagat
     7321 gttaccattt cgtgatcact cgcagactct ctggcaagag aggtatcgct tataatgcct
     7381 gcggtatatg atactccgtc accacgcgtc aactttgaag aaagccagta ttggcgaact
     7441 cccattgtcc atgtccagtg atcggcgaat cgccagtcat tttgtgcgaa tagtgagact
     7501 gtactttgct ctgactcata ataggagcga gttcgtgttt ccttattaat gaagccggtc
     7561 agagatttgc ttgaggtcat gccaccggac ctttggctga ccctgtcttg tttgtactgt
     7621 gcaccggtaa caagttcatt attagcaggc agcgaaaagt gactctgcaa tgtgaccgcc
     7681 tgagtgtatt gcttatcatg ggtgtcagtc ttgttatgaa cggtcagagc ctgaatcatc
     7741 ggactgggaa caggctgtgt cgtttttact tcgttggcaa attggcgctg gatggtctgc
     7801 tcatacgcgt cgaaatgaat tttttttaga tagtcaccgt ccacgtctgt gtcatagaat
     7861 accccaactt tctctcgttc aagtttaggt attttgacac taaatgcctc atagcttccg
     7921 tctggatcct catagtaagt ttgcgtcgcg agtctgtagc gatcaagcga gaggccaaaa
     7981 cgatggtttc cggagttata acccaaccat acaccctgac tattgttacg atagttggta
     8041 ttcggcagac gtccatccgg cgtatcacga ttgccctgat cagaataact accgttgatg
     8101 cgataatcaa atccaccgat gctcccctgg accgcgattg attcttccca gcctgctgtt
     8161 gcggaattat aaacagcttt cacaactcca gatgcaagtt tgtcacctcc ctttttggtt
     8221 atgaagttaa caataccgcc aattgcctgt gaaccgtaca gtacggaata tggacctttc
     8281 actacctcaa cacgctccag cgcagactca tctatcaaca gtcccacacc ataattatct
     8341 ccggcgcgct gataagttac ctcctgacca tcaatgagaa ttaaaacacg ggaggatgct
     8401 tcgccacgaa tgcggatttg tttacggcct gccaaggagt tgtctgttat ctctactccg
     8461 gggatgtcct gcaaattatc ggctatggag gcattggtgg agttctgcaa tgtttgttgg
     8521 tcaataacct gtatagtcgc cgggctttcc caaaggttgc ttgccgaacg attcgtggtc
     8581 acgacgagcg tctcttcgtt gctgattttt gtttctgaag aagttgcggt tgcagtagaa
     8641 actatcccag aaatgcataa tgacagagtg gaaaggatat aaattcgaca aggtatatta
     8701 tataacattt catccctcat taatacaaag tacaaatgat tgctgtaatg ataattatta
     8761 tcatttatgt tctcatgtat ctgtgattat tgtcatcttc ataaattgta aatatcaaac
     8821 atttttgacc ttaatcatgt tttttgatag atattttacg actgaacata tccgtcgttt
     8881 cctctgactc gtgtcagtcg gtctctggtt gtatccacgg accgtactct tgacataaga
     8941 gtgcggtccg tggaaaacgg agttgaaaaa atggtgtctg aaagaaggta ccatcattgc
     9001 gatgacaaac actttggcgt ggataatgta attaattgct gaaattgacc gtatatgcgg
     9061 taagactcat atcagtatca ggtccggtta attgctgata ctgacataaa ctttttacaa
     9121 aaggatgaat gcagaaggtt actctaatgg ccagagtgat gacaatgatg gtcagacgtt
     9181 gacctgcaga aactgcattt taattggtct ataaagtctg caagaggaat cagggtcaga
     9241 tcagtgagtc ttatcgcggc ccgaagctat gactgaaaga aggctggata cagaattgca
     9301 acaatttggc aatgtcagaa cacagaagct ttgcaagcag gtgaaaggtt atgtctagaa
     9361 aaaggagtat atcagaatac atctactgat gtacaaaaca caacaatagc ttcatgatat
     9421 ataaatacgt gatgacgagt tgtactccgc atggttattt aacttctcag caccactaat
     9481 gatcctgagc aacttcgtat ttgggccatt gccatggagt agaaagctgt gtctgagaat
     9541 gcagaatttg agaaaagaat tcgctttctt ggagagcttc tgaaaatggc acgctaacaa
     9601 cgctttgtta aaaaatgtga atcacttgcc gaggctgcat tttctattcg aggagaatgt
     9661 tgacgtagat attacagaaa tctcagcgca tcaggataaa ctgctacctt aggtcaacca
     9721 ccaaaagaaa atacaatacg tccagtttgt atgcctttaa taacacatct tttaaatgtt
     9781 gaagaattat cccgcctgct gaagaacgtt gctctgagtg tgataaacct ttttattctt
     9841 gatgatgtca gcgagaagat ggaatatatc cccgactggg tcgtggttac ccggttaaac
     9901 atctggtggc gctaataaat ctggcaagtc acattctgtt gaatgctgtg acagtgcctt
     9961 accgagagag cgaaattgtg gtgttctagt gcatagtcgc caccattccg gataatttta
    10021 ttgcgttgtt ttacaacttc ttttacagcg cagatctgtc gctgacgttg aatcaatagc
    10081 ctggatttca gaacacaatg cccgtttgct ggttggtccg gcagtagcat taattcatta
    10141 tctgaatgaa atgtgtcaat ccacagaaac cgctgtcaat gacgcatttt gtcggacgtt
    10201 aacacgagaa agtctggcta ttccgtaatg ccatcttatt tcgtaatgga ttgagaatgc
    10261 tggattttta attatattac gcgcagtatt aatcgcgtaa atgttttgcg gtcagcaacg
    10321 gtgggggatc cattgctctg ttcaatgaat accatcatac atttgaatca ggagtcggta
    10381 tgatgatttt ggtgacggga ggcgcacgga gcgggaagag tcgccacgca gaggtgctta
    10441 ttggggactc ttcacaggtt ctgtatatcg ctacctcgca aatccttgat gatgagatgg
    10501 ctgcacggat agaacatcat cggcaaagcc gcccggagca ctggcgcaca gtggagcgct
    10561 ggcaacatct tgatgaatta attcatgcag acattaaccc gaatgaggct gtgttgctgg
    10621 aatgcgttac cacaatggtg actaatctgt tgtttgatta tggcggcgat aaagaccctg
    10681 atgaatggga ttatcaggcg atggaacagg cgattaatgc tgagattcag tcgttgattg
    10741 ctgcctgcca acgttgcccc gcaaaggttg tattagtgac taacgaagtg ggaatgggga
    10801 ttgtgccgga gagtcgtctg gcacgacatt ttcgtgatat tgccgggcgg gtaaatcagc
    10861 agttggccgc tgcggcaaat gaagtatggc tggtggtttc gggtattgga gtaaaaatca
    10921 aatgagtaaa ttattttggg cgatgctctc atttattacg cgtctgcctg taccgcgtcg
    10981 ctggtcccag ggactggatt tcgagcatta ttctcgcggt attattactt ttcctttgat
    11041 tggattattg cttggcgcga ttagcgggct ggtcttcatg gtgctgcagg catggtgtgg
    11101 cgtaccactg gcggcactgt ttagcgtact tgtgctggcg ctgatgaccg ggggattcca
    11161 tctggacggc ctcgctgata cctgtgatgg cgtattttct gcacgtagcc gcgatcgcat
    11221 gttggaaatc atgcgtgata gccgtttagg cacccacggc ggtctggcat tgatttttgt
    11281 ggtactggca aagattctgg tgttaagcga gttggctctg cgtggcgaac cgatccttgc
    11341 atcgctggcg gcagcatgtg cggtcagccg cgggactgcc gcattattga tgtatcgtca
    11401 tcgttatgcg cgggaagaag ggcttggcaa tgtgttcatt ggcaaaattg atgggcgaca
    11461 aacctgcgtc acactcggct tagccgctat ttttgctgcc gtattattgc cgggtatgca
    11521 tggtgtggct gctatggtgg tgacgatggt ggcgattttc atcctcggtc agcttctcaa
    11581 acgtacgctg ggcgggcaaa cgggcgatac gctgggagca gccatagagt ttggtgaact
    11641 ggttttcctg ctggcactgc tataaagaga cgtgacatgc aaatacttgc cgatttactg
    11701 aatacgatcc cagccatcaa ttctgccgct atgtcgcgtg cacaacggca tgttgacggg
    11761 ttactcaaac ctgttggtag cctgggaaag ctggaggcgc ttgccataca actggcagga
    11821 atgccggggt tgaatggcat accgcatgtg ggcaaaaaag cagtactggt tatgtgtgcc
    11881 gatcacggcg tctgggagga aggggtcgct atttctccaa aagaagtgac agccatacag
    11941 gctgaaaata tgacccgtgg aacaaccggc gtgtgtgtgc tggcagcaca agcgggcgct
    12001 aacgtccacg taattgatgt tggtattgat actgctgagc ctatccccgg gcttatcaac
    12061 atgcgtgtcg cacgaggtag cggcaatatt gcttcagctc cggcaatgag tcgccgtcag
    12121 gctgaaaagt tgcttttgga cgtcatatgt tatacgcggg agctggcaaa aaacggtgtc
    12181 acgctgtttg gtgtaggtga actggggatg gcaaacacga caccggcagc ggcaatagtc
    12241 agcacaatca ctggccggga tcctgaagaa gtggttggga ttggcgcaaa cctgccgaca
    12301 gataaactgg ctaataaaat tgatgttgtg cgtcgggcga ttacgttgaa tcaaccaaat
    12361 cctcaggatg gtgttgatgt cctggcaaaa gtgggtggat ttgatttggt cggaatagct
    12421 ggagtgatgt taggtgctgc ttcctgcggt ttacccgtgt tgctggatgg atttctttct
    12481 tatgctgctg cgctcgcagc ctgccagatg tctcctgcaa tcaaaccgta tctcattcct
    12541 tctcacttgt cggcagaaaa aggcgcgcgt atagcgctct cgcatttggg gctggagcct
    12601 tatctcaata tggatatgcg tttaggtgag gggagtggtg cagctctggc gatgtccatc
    12661 atcgaagctg cttgtgcgat atacaacaac atgggcgaac ttgctgccag taatattgtt
    12721 ctaccgggga atacgacttc tgatttgaac agctaaaaac gaaaagtctg ataaaagcta
    12781 tacttatcgg atagtattcg cgacttagga aagggacatg atgcgtcgtg taaatattct
    12841 ttgctcattt gctctgcttt ttgccagcca aaatagcctg gcggtaactt atccattacc
    12901 tccagagggt agccgtttag tggggcagtc gcttactgta actgttcctg atcacaatac
    12961 tcagccgctg gagacttttg ccgcacaata cgggcaaggg ttaagtaata tgctggaagc
    13021 gaatccgggc gctgatgttt ttttgccgaa gcctggctca caactcacca ttccgcagca
    13081 actgattttg cccgccactg ttcgtaaagg gattgtggtt aacgtcgctg aaatgcgtct
    13141 ttattactat ccgccagaca gtaatacagt ggaagtcttt cctattggta tcggccaggc
    13201 tgggcgagaa accccgcgta actgggtgac taccgttgaa cgtaaacaag aagcaccaac
    13261 ctggacgcca acgccgaaca cccggcgcga atatgcgaaa cgaggggaga gtttgcccgc
    13321 atttgttcct gcggggcccg ataaccccat ggggctgtac gcgatttata ttggcaagtt
    13381 gtatgccatc cacggtacca atgccaattt tggtattggg ctccgcgtaa gtcagggctg
    13441 tattcgtctg cgtaatgacg atatcaaata tctgtttgat aatgttcctg taggcactcg
    13501 tgtacaaatt attgatcagc cagtgaaata cacaacggaa ccggatggtt caaagtggct
    13561 ggaagttcat gagccgctgt cgcgcaatcg tgcagaatat gagtctgacc gaaaagtgcc
    13621 attgccggta accccatctt tgcgggcgtt tatcaacggg caagaagttg atgtaaatcg
    13681 cgcaaatgct gcgttgcaac atcgatcggg aatgcctgtg caaattagtt ctggttcaag
    13741 acagatgttt taagagcgtt ggtaattaga aagtaaaaag cctgctcgaa agcaggcttt
    13801 tttgaa
//
LOCUS       DAPOXO010000111        13765 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.111, whole genome shotgun sequence.
ACCESSION   DAPOXO010000111 DAPOXO010000000
VERSION     DAPOXO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13765
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.111"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            252..1038
                     /locus_tag="ROH59_004343"
                     /pseudo
     CDS             252..1038
                     /locus_tag="ROH59_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313311.3"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
     gene            complement(1179..1952)
                     /gene="uxuR"
                     /locus_tag="ROH59_004344"
     CDS             complement(1179..1952)
                     /gene="uxuR"
                     /locus_tag="ROH59_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HDX4806748.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNTDSPDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(2167..3627)
                     /locus_tag="ROH59_004345"
     CDS             complement(2167..3627)
                     /locus_tag="ROH59_004345"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HDX4806749.1"
                     /translation="MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPDYRKAAFALMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL"
     gene            complement(3708..4892)
                     /gene="uxuA"
                     /locus_tag="ROH59_004346"
     CDS             complement(3708..4892)
                     /gene="uxuA"
                     /locus_tag="ROH59_004346"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDX4806750.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAE
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            5232..6575
                     /gene="gntP"
                     /locus_tag="ROH59_004347"
     CDS             5232..6575
                     /gene="gntP"
                     /locus_tag="ROH59_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HDX4806751.1"
                     /translation="MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(6749..7651)
                     /gene="fimH"
                     /locus_tag="ROH59_004348"
     CDS             complement(6749..7651)
                     /gene="fimH"
                     /locus_tag="ROH59_004348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria D-mannose specific adhesin FimH"
                     /protein_id="HDX4806752.1"
                     /translation="MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVN
                     LAPAVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSS
                     YPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNS
                     DDFQFVWNIYANNDVVVPTGGCDVSAHDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYL
                     SGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTAN
                     YARTGGQVTAGNVQSIIGVTFVYQ"
     gene            complement(7671..8174)
                     /gene="fimG"
                     /locus_tag="ROH59_004349"
     CDS             complement(7671..8174)
                     /gene="fimG"
                     /locus_tag="ROH59_004349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimG"
                     /protein_id="HDX4806753.1"
                     /translation="MKWRKRGYLLAAILALASATIQAADVTITVNGKVVAKPCTVSTT
                     NATFDLGDLYSFSLMSAGAASAWHDVALELTNCPVGTSRVTASFSGAADSTGYYKNQG
                     TAQNIQLELQDDSGNTLNTGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQAVI
                     SITYTYS"
     gene            complement(8187..8717)
                     /gene="fimF"
                     /locus_tag="ROH59_004350"
     CDS             complement(8187..8717)
                     /gene="fimF"
                     /locus_tag="ROH59_004350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimF"
                     /protein_id="HDX4806754.1"
                     /translation="MRNKPFYLLCAFLWLAVSRVLAADSTITIRGYVRDNGCSVAAES
                     TNFTVDLMENAAKQFNDIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLA
                     LENTVSAASGLGIQLLNEQQNQIPLNAPSSALSWTTLTPGKPNTLNFYARLMATQVPV
                     TAGHINATATFTLEYQ"
     gene            complement(8727..11363)
                     /gene="fimD"
                     /locus_tag="ROH59_004351"
     CDS             complement(8727..11363)
                     /gene="fimD"
                     /locus_tag="ROH59_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher FimD"
                     /protein_id="HDX4806755.1"
                     /translation="MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSS
                     AELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSE
                     QGIVPCLTRAQLASMGLNMASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTI
                     PQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIG
                     AWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGI
                     NFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIND
                     IYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEK
                     PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD
                     DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV
                     IQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRSSTLYLSGSHQTYWGTSNVDEQFQAGL
                     NTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMS
                     HDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI
                     GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTD
                     WRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL
                     LMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCI
                     ANYQLPPESQQQLLTQLSAECR"
     gene            complement(11430..12155)
                     /gene="fimC"
                     /locus_tag="ROH59_004352"
     CDS             complement(11430..12155)
                     /gene="fimC"
                     /locus_tag="ROH59_004352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418736.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HDX4806756.1"
                     /translation="MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATR
                     VIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLR
                     ILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPP
                     DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAG
                     SNITYRTINDYGALTPKMTGVME"
     gene            complement(12192..12731)
                     /locus_tag="ROH59_004353"
     CDS             complement(12192..12731)
                     /locus_tag="ROH59_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418735.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX4806757.1"
                     /translation="MKRKRLFLLASLLPMFALAGNKWNTTLPGGNMQFQGVIIAETCR
                     IEAGDKQMTVNMGQISSNRFHAVGEDSAPVPFVIHLRECSTVVSERVGVAFHGVADGK
                     NPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATG
                     RRVTGGIANAQAWFSLTYQ"
     gene            complement(12796..13344)
                     /gene="fimA"
                     /locus_tag="ROH59_004354"
     CDS             complement(12796..13344)
                     /gene="fimA"
                     /locus_tag="ROH59_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HDX4806758.1"
                     /translation="MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAAC
                     AVDAGSVDQTVQLGQVRTASLKQAGATSSAVGFNIQLNDCDTTVATKAAVAFLGTAID
                     ATHTDVLALQSSAAGSATNVGVQILDRTGAALALDGATFSSETTLNNGTNTIPFQARY
                     FATGAATPGAANADATFKVQYQ"
BASE COUNT         3403 a         3535 c         3257 g         3570 t
ORIGIN      
        1 attaatatag acatcaatat agcaacatca aattccaatt agtaataaga tatgctttta
       61 aattgcatgc aaataatttt aaatgagcgt tttttgatac tttagagtgt ttcccaccat
      121 ttaatatcac tgtgtagagt tgatatcact acaacagaaa catgcatgtc atttgtttac
      181 ttctcttttt actacagaaa aatttatcta tttttctaag catcagtgaa atactcataa
      241 aggtaactat tatgtctatg ccattaagca atgcccttca gagttaaatt attacagata
      301 atcacttcct tcatcatcca aaagtcgaca gtgagttaac acgtaaacat gaacgtgcac
      361 gcatggatac ggaaaatatc tatcttccgc ctcttgctcg tggcaataac cataattacg
      421 atggaaaaag cgttgtcgaa attagaaaac ttgatattag taaagagtcc tggccattta
      481 attatgtgac agaaacatgc agagaattca atggtattac aacaacagga cgtatgctct
      541 atcgaaactt gaaaatcacc tcagctttag acgaaatata tggtggtata tgtaaaaagg
      601 cgcatgctgc cacagagtta gcaaaaggat tacggctaaa tttatttatg aaaggccctt
      661 tcgatcctgt tgaggactat acagttcatg aaataacatt aggccctggt tgcaatgttc
      721 ctggttatgc cggaaccacg ataggatata tttcaaccct tccagcttct caggcaaaaa
      781 gatggaccaa tgagcagcca aggattgata tctatattga tcagataatg acggtaacag
      841 gggtagcaaa ttcttccgga ttcgcccttg ccgcatcact taatgctaat attgagttgg
      901 gtaatgaccc aataattggt atagaagcct atcccgggtg atgaaaatgc accactcaaa
      961 cgtatgactc tgcaaccgtc atctcttcca gaactgtttg aattaaaaaa tggtgaatgg
     1021 aattatattg gtaaataact accaggaaga atgagtacta acattcaggt tatacagata
     1081 gctaaacaat cccctgcaat ttacaaagta atactcattg cgacttctta atttaagaaa
     1141 gcgcaaggaa cgtttaccct tgcgcttatt ataataagtc aggcgtcgac tttatccagc
     1201 ggccatgaat caaacagata gccatcaaaa taaatatcgt caacgttcga gaattccagc
     1261 agacgttgct taacgttttc cagatgctgc cacattgcca gcttcgccgc tcgggcatct
     1321 tttttgatta acgcggcgag gatctgtttg tgatcgccca accactcttt gcgatacagg
     1381 ctgtcatcca gatggctgtg caactggatc cacattggat tgttttcccg ccactgccag
     1441 gactgacgga acagctccac cagcatgctg ttatgcgttg cttcggcaat agcgagatgg
     1501 aactgcatgt caccgctttc gctgctgccc ggcgcactgg aagccagttc acgctcttcc
     1561 agttgcaatg cctgacgcat tttgacgata tcttcgcggg tagcctgcag ggcggcaaac
     1621 tcggcgatgt tgctctcaag aagctgtcgc gcctgcaaca gctcaaaagg acccgcatca
     1681 ttgcaaacgt tggcatccgg actgtctgtg ttgtggctgc ctgagctatc aagaacatag
     1741 ataccggcac cccggcgcac ttccaccagc cctttgatct ccagcatgat cagcgcttca
     1801 cgtaccaccg tccgcgtgac atcaagcatt tctgcaattt cacgctccgg cggcaaccgt
     1861 tcgccaggat tgtacggcgt ctttatgatc agatcgcgga tcatcgcccc gacttcctgg
     1921 taaggtcttt gcgcagaggt ggcagatttc atggtgttgt gtccgttagg tgcggttaat
     1981 caaatttttg ccggatgcgg cgtgaacgcc ttatccggcc tacaacgggc aattttacgg
     2041 cacccgttaa tctcaaacta taccattagc actggaagtt ggcacgtaca ggtgggcaaa
     2101 aaaacgaaaa ctggtcaacc aaatatcagt ttgattgacc agtaagtctg tagggtaatc
     2161 agttagttac agcgcagcca cacactcgcg cgcaccgcgt tcgcacagct gctgatatgc
     2221 cgccgtcacc gcgccaacaa agtcggcatt ctgcggcaga tcatcggcaa aaataccgct
     2281 caggcccagc agcgctttca cgcggtctgc gccctgatac tgcgcgttaa tcttctggaa
     2341 ctcggccagc atcgggtcga ccacgtcaat ggcattaccc tgctcatcca cgccctgggt
     2401 gtaacgcatc cagccagcca cgcccagcgc caggtgacgc cagctgccgc cgttttgcag
     2461 gtgcagacgc accggatcca gcagacgctg cggtaacttc tggctgccgt ccatcgcaat
     2521 ctgccaggta cggtgacgca gagacgggtt gctgaaacgc tcgatcagca gcgtcgcata
     2581 ggcgttcagg tccgtacctt ccggcatcga cagcgttggc gcttgttcct gcatcatcag
     2641 ggcaaaggcc gctttgcgat aatccgggtt agtcatggtg tcggcaatag tttcatagcc
     2701 gccgaggtaa ccgaggtatg ccaggaaaga gtggctgccg ttcagcatac gcagcttcat
     2761 catttcgaac ggcacaacgt ctgcaacgaa ctgtgcgcct actttatccc agtccggacg
     2821 accattaacg aagttatctt caatcaccca ctgacggaac ggttcgcagg caatggcgca
     2881 cgggtcataa acacccagtt ggtcagcaat ttcctgtaag gtttctggcg tcgccgccgg
     2941 aacgatgcgg tcaaccatgg tgcacgggaa ggtgacgttc tcttcaatcc atgccgccag
     3001 ctgcgggtca cgcgcctgag ccagccccag taccgcgacc ttcgccacat gaccgttttc
     3061 acgcacgtta tcgcaggaca tcaccgtaaa cgctttcagc cctttttcac gacgcagacg
     3121 cagggcttcg acgatgtaac caatcgcgga cttcggcgca gtcgggtttt ccagatcgtg
     3181 cttgatcagc gggttattga gatccagttg accgcttgcc gcatcagcgc agtagccttt
     3241 ttccgtgacc gtcagagaga caatcgccgt ttgcggacgc gccatcgcgt tgagaatacc
     3301 ttcgcagccg tcgatttccg ggtgcagcgc ttctttcatc gaaccgataa ttttcagctc
     3361 ggtgctttcc gcgccttttt ccgccacggt gtacagcagt tgctgttttt tcaggttttc
     3421 gatcagcacg cggtcgttgc ctggcatcag gttaacttcg cagatacccc agtcgctgtc
     3481 ggtgctttcc agcagatgat gggtgtacag cgcctggtgc gcacggtgaa acgccccgca
     3541 accgagatgc acaatgcgtg attccagacg agaatgatcc catgacgggc gggcaaccgg
     3601 cagattgctg tcaacaatag tagtcatcgt aaactccaga atccgtcttc agagagtgac
     3661 ggcaaggaag aaggaaccgg cacggcgcgc agccatgccg gtggatatta acggctaaag
     3721 aaagcgcgct ggatcgccag ttcgacaccg cgaacttcgg ccaggccttt cagacgacca
     3781 attgcggagt aacctgggtt ggttttcttc ttcaggtcgt ccagcatctg atgaccgtgg
     3841 tccggacgca tcgggatcag gtcttctttg ccttccgctt tacgacggtg ttcttcttca
     3901 acaatcgctt tcaccacttc gtacatatca acgtcaccgt tcaggtgcgc cgcttcgtgg
     3961 aaggttttcg ggttatcttc acgcatggtg gagcgcagat gggtgaagta aatacgcgga
     4021 ccgaactgct tgatcatatc aaccagatcg ttgtcagcac gcacgccgta ggaaccggtg
     4081 cacatggtga aaccgttcgc catgctattt acggtatcaa ccatccactg catatcttca
     4141 atggtagaaa caatgcgcgg caggccgagg attgggcgcg gcggatcgtc cgggtgaaca
     4201 gccatacgca cgccaacttc ttcggcaacc ggaataatcg ccttcaggaa gacggcaaag
     4261 ttttcgcgca gtttggcttt gtcgatatct ttgtacagct ccaggtgctt acggaactgg
     4321 tcgagggtgt acccttcttc cgcgcccggc agaccggcaa tgatgttacg ggtcagacgc
     4381 gctttgtctt cgtcgctcat agtggcgaag cgttcagctg cctgagcaat ttcttcttcg
     4441 gtgtaatccg cttccgcacc tgggcgtttc aggatatgca tttcgaatgc agcgaattcg
     4501 atctggtcga agcgcagagc tttggagccg tctggcagca cgtattcgag gtcagtacgg
     4561 gtccagtcga gcaccggcat gaagttgtag cacacggtgc gaataccgca ctgcgccagg
     4621 ttgcgcagag tctgctgata gttagcgatc cactgctcat agttgccagt gtgggttttg
     4681 atatcttcgt gaattggcac gctttctacg acagaccaca ccaggcctgc atcttcaacg
     4741 atagccttgc gtttgaggat ctcttcaacg gaccatactt cgccgttcgg gatatggtgc
     4801 agcgcggtaa ccacgccagt tgcgcccgcc tgacggacat cagctaaaga aaccggatcg
     4861 tttgggccgt accagcgcca ggtctgttcc atgatttttc ctctttcaca tagtgggttc
     4921 cacagcaaag agacgcggaa ccctggagtt gtttaggtat ccggatgaac aaccagaccg
     4981 cagccgtggc gttgcatcgg atgagatggc gtataagttc taccttttgg taatacatgt
     5041 caacccgaat tctaaaattg gttaaccaca tcacaagaat ttcactctcc tggttgttgc
     5101 tgcaaattgc agcaaagggt aatcgatggt tattgatcag aggatgtgac attcatcgca
     5161 acaatggttg accaatttac ataacatgtc gcccaaaata acaacggttc aaccaggtaa
     5221 ggtaaaacgt tatgcatgtg cttaacattc tctgggtggt attcggcatt ggtctgatgc
     5281 tggtactgaa tttgaagttc aaaatcaatt caatggtggc tttgttggtg gcggcgctgt
     5341 ccgtcgggat gctggcgggc atggatttga tgtcgctgct gcacaccatg aaagcgggct
     5401 tcggcaacac gctgggggaa ctggctatca tcgtggtgtt cggtgcggtc atcggtaaat
     5461 tgatggtcga ctccggcgcg gctcaccaga tagcacatac gctgctggcg cgtctcggtc
     5521 tgcgctatgt acagctgtcg gtgattatca tcggcctgat ttttggtctg gcgatgttct
     5581 atgaagtggc ctttatcatg ttagcgccgc tggttattgt cattgccgcc gaagctaaaa
     5641 ttccgttcct gaaactggcg atcccggcag tagcagctgc cactaccgca cattcactgt
     5701 tcccaccgca gccgggtcct gtggcgctgg tgaatgctta tggcgcagat atggggatgg
     5761 tttatatcta tggcgtactg gtgacgatcc caagtgtaat ctgcgcaggt ctgatcctgc
     5821 cgaagttcct cggcaatctt gagcgcccaa cgccatcatt cctgaaagca gatcaaccgg
     5881 tagatatgaa caatctgccc tctttcggcg tttcgattct ggtgccgctg atcccggcga
     5941 tcattatgat ctctaccacc atcgccaata tctggctggt aaaagatacc cctgcctggg
     6001 aagtggttaa ctttatcggt tcctcgccga ttgcaatgtt tattgcgatg gtggttgcat
     6061 tcgtactctt tggcaccgca cgtggtcatg acatgcagtg ggtgatgaac gcttttgaaa
     6121 gtgcggtgaa aagcattgca atggtgattc tgatcatcgg tgcgggtggc gtgttgaagc
     6181 aaactatcat cgacaccggc attggcgaca ccatcggcat gttgatgtcc cacggcaata
     6241 tctcgcccta cattatggca tggctgatca ctgtgctaat tcgtctggcg acgggtcagg
     6301 gtgtcgtttc ggcgatgacc gccgccggga ttatcagtgc tgcaatcctt gatccagcaa
     6361 ctggtcagct ggttggcgtg aatccggcgc tgctggtact ggcgacggct gcgggttcca
     6421 acaccctcac ccacattaac gatgcatctt tctggttgtt caaaggttac tttgacctgt
     6481 cagtaaaaga cacgttgaaa acctggggtc tgctggagct ggtcaactcc gtggttgggc
     6541 tgattattgt gttgattatc agcatggtag cgtaaaagag cacctgagcc tgccattggc
     6601 aggctctgtt cggattgtcg gcaaagtgca ctttgtttat gccagatgcg acgctggcgc
     6661 gtcttatctg gcctacaaag ggctaacgtg cagtttttta gcttcaggca atattgcgta
     6721 cctgcattag caatgttctg tgatttcttt attgataaac aaaagtcacg ccaataatcg
     6781 attgcacatt ccctgcagtc acctgccctc cggtacgtgc gtaatttgcc gttaatccca
     6841 gacttaccgc cgaagtccct actgctccta acgataccgt gttattcgct ggaataatcg
     6901 taccgttgcg cgtcaactgt acgccgacgc cctgcgctgg tgaaaacgac gcggtattgg
     6961 tgaaaatcga gttgcccgca tctgcggttg tgccggagag gtaatacccc aggttttggc
     7021 ttttcgcaca ataaacggta agaggaattg gcactgaacc agggtagtcc ggcagagtaa
     7081 cggtgacatc atgagcagaa acatcgcagc cgccagtagg caccaccaca tcattattgg
     7141 cgtaaatatt ccacacaaac tggaaatcat cgctgttata gttgttggtc tgtcgcaaaa
     7201 taagcacggc aattaatgag ccagctttaa tcgccacccc acccgcactg ctcacaggcg
     7261 tcaaataaag cgccaccggc cacggcttat ccgttctcga attataaaca acccgcggcg
     7321 tttcgctggt agtcggaaat ggatagctac tgccactata ttttacggtc ccggaaaaat
     7381 tagataacac gccgccataa gccgagcctc gttgcagtgt gacatagtct gtaatggttt
     7441 ccggataatc gttatggcaa aagatttgcg tcgaaagatc tacgaccagg ttttgcccca
     7501 cattcacggc aggcgcaagg tttacataaa cattagcgct gccaccgcca ataggaatag
     7561 cggtaccatt ggcggtttta caggcgaatg accaggcatt taccgaccag cccatcagca
     7621 gtacagcaaa cagggtaata actcgtttca tgacaattat ctcttcgggt tcagctgtag
     7681 gtataggtga tgctaatcac tgcctgaatg gttccctgag tggctccgcc atttaccgtc
     7741 aatgctctga cctgtaacgg gaagtgcgct gattgtgagg aatcatccac ctgaactgtt
     7801 ttggttgcgc cagtattcaa tgtgttgcca ctgtcatcct gtagctctaa ctggatgttt
     7861 tgcgcggtcc cctggttttt ataatatccg gtactgtcgg ctgccccgct gaagctggca
     7921 gtgaccctcg acgttcccac cggacaatta gtcaactcaa gcgcaacatc atgccaggcc
     7981 gatgccgccc cggcagacat cagactgaaa gaataaagat cgccgagatc aaacgtggca
     8041 ttggtggtgg aaaccgtgca cggtttggcg acgaccttac cgttcaccgt gatggtgaca
     8101 tcggctgcct gtatcgtcgc acttgcgagc gccaatattg ccgccaataa atacccacgt
     8161 ttgcgccatt tcatgagcat ctccagttac tgatattcaa gagtgaaggt agccgtggca
     8221 ttgatatgcc ccgcagtgac aggcacctgt gtcgccatta gccgggcgta aaaattcagc
     8281 gtatttggtt tacccggcgt cagggtcgtc cacgaaagcg cggacgatgg agcattaagg
     8341 ggtatttgat tttgctgctc attcagaagc tgtattccca gtcccgaagc cgctgacacc
     8401 gtattttcaa gtgcaagcag gttggcattg tggctatctg caacaccggt aaacccaact
     8461 tttacggcag aaacggcatt accacagggt gacagcaaaa tacgaaatgg aacgacagga
     8521 gtcgtcgcgc caatgtcgtt aaattgcttc gccgcgtttt ccatcaaatc aacagtaaaa
     8581 ttggttgatt cagcggccac actacagccg ttatctctga catagccgcg gatagtaatc
     8641 gtgctatccg cagccaaaac gcgacttacc gccagccaca aaaaagcgca cagaagataa
     8701 aaaggtttgt ttctcatcac gcccccttaa cgacattcag ctgatagctg ggttaataac
     8761 tgctgctgac tctctggtgg cagttgataa ttggcgatac agtgagcatt ttcctcttct
     8821 ccccatttca cctgaacttt tcccgctaaa ggcattccgc tgaggtaaac ctgaccatta
     8881 tccgcaacaa tgccgctact ctggctactc tctgatgtca ccatcgcccc aaacggcagc
     8941 ggcttattat tgtgggttag cgtcatgagc agttttatcc caacgcgcgc tttaaactct
     9001 gctcgcacga tcgccccacg agtgggaaca acgttagcga ccgcgttatc taaatcgacg
     9061 ttatcagcca gggtattggt atccagcgcc actctgtttt cccgatattc ggtggcataa
     9121 ggcagcacgg cataaccgcg ccagtcggta cgcacccccg tctggttttc gacttttgca
     9181 tcttttgcgc caggcgcttt aacaagtacc accgtatcgt ttaacggctg ccccagcgtt
     9241 acgccattgg catgagccag taccccaccg ctgactccgt aatagagctg cttaatatca
     9301 tcgctatggc tgtaaccgat attggcattg ccgtaaccac cgcgataatt cagcgtggcg
     9361 tagcctgtac ttccgctatt tccatcgcct cccccggcat agccggtttg cacgctatag
     9421 ctgaggttgt tgtcttccag caacgtaccg tatacaccag ccagattggt catccgaccg
     9481 ttgagatcgt gtgacatgct gtagctggca ctggcatgtc gccactgaga tttactgtca
     9541 gaacgcagcc agtggctgaa aggaatattg acgttaagcg ctaacatctg atcccgtcct
     9601 ttttgccagg cgtttttcgt caggctatag ctgagcgtcc agttgatatc ttcgaacgca
     9661 gtatttaatc cagcctggaa ttgctcatcg acattactcg ttccccaata agtttgatgg
     9721 ctaccactca aatacagtgt tgatgagcgc ccgagttgct gagtaacggt gagttgtaat
     9781 ttcccgcgtt tgttataagc gaggttgtaa tagtcggtga atttcggctt aacctgaata
     9841 acaccatcct gtgtttcgat gttgtagcca ttcattcgac tgtatgttgt atcagcgaaa
     9901 ttaaaatatc cgctggtcga ataacggtaa cccactaact gaatattcgt gcctgactca
     9961 ttgagcgatt tgttatagag aaaacgcacc gattgtccgt catgctgact gtcatcggga
    10021 agtgtggaat tagcctgcgt catatccaca gacagagcac ccagcgcccc catgtttttc
    10081 ccgataccga aattaaaagc acgataacga tccgccagtt gcgttccacc atatattgtc
    10141 cagccagccg gaaggccgtg gagtaatgta ctctggaaaa agcggggttt ttcctgttgc
    10201 gcatttccac tacggtattc tcctgccgta atggaataac gagtatgccc ttcacgttgc
    10261 aaaagcggga ctgacgaata gggtacggta aaaatctgcg tgctgccgtc agcctctttg
    10321 atcgttacct gcaagtcacc actattacct gcggcataga tatcgttgat ggtaaaaggc
    10381 cccggtggca ccgtactatt ataaatgtca tacccatttt gtttaatagt gacctgtgca
    10441 gtaccacgag caataccgtg gatcaccggg gcaaatcctc tttgactatc gggtaacata
    10501 ttgtcatctg aggccaattg tgcgccgcga aagttaatac catcgaaaat atcgccctga
    10561 gtataaccat cacccagcgt cagccgggaa cgtaacggta ttatgtctcg ctcaagccag
    10621 gtattgatat gctgccattt atttttgcta cctgatgatc tgtcgctact gttataactc
    10681 caggtggtat tgtcgcgtaa acgccacgca ccaatattta acccactctg taggtttaaa
    10741 tatgcataat ggctgttacc cccaatccga ttctgtacac tatttccgct gaaattataa
    10801 ttgagcaatc cggcattaat accgggatcc cataactcag gaggaatata accacgcgcg
    10861 cgattactca taaatgcctg agggatcgtc aggttgagtc gctgctgacc aacatctaaa
    10921 tgcgcagtag cgtcctggac cattgtggtt aatggcacac aggcatcatc cgccagcaga
    10981 ttcataccgg cgacagaagc catattcagc cccatactgg cgagttgcgc gcgtgtcagg
    11041 cagggaacaa tcccttgttc actgtcgccc gtattaaatg tgacatcacg cgttgccata
    11101 taaccattat tcaaatagat atcgacgcga tacgtccctg gcggtaattc ttgtccattt
    11161 tcaaaacgcg ataaatcagc cacagcctgg ggatcatccg ctaaaaagcg cgggttaaaa
    11221 tagagttcgg cagatgacaa aggtgcctgt gcggcaaaag cacaggcaac aaagagccgg
    11281 acaaaaaaac cagccaaacg atgcttacga atatgcaagc attgtgtgtt tcgctggtaa
    11341 agtcttaaat tcagatatga cattattcct ccggtttaaa atcacccggc agtcaattct
    11401 ttttattcag gcgaaaaatt ccccctgcgt tattccatta cgcccgtcat tttgggggta
    11461 agtgcgccat aatcatttat tgttcggtaa gtaatattgc ttcctgcatc agaaggcaat
    11521 ttaaccgtgc tttcgcccat tggaggcacc aatgcatttt caagaacccg ggttccggca
    11581 ttcaactctg ttaccgtcag gtaatagggt gtcgggttaa tcagcgtcag agaattcgcg
    11641 ctacgacgaa atcttaattt ttctgcggcc tgatcgggtg gcaacgctaa tttagccgga
    11701 cgatagtaca gtttaatgcg gctgataatt gcgagctgta gcgtattctc agtcaatttt
    11761 gatttatcca ttgacggaat cgctttaacg ttcatccaga ataaactttc ccggtcctgt
    11821 ggcaattggt tatttgttgc atcaagaata cgcaaggtat tctctttttt tcccttcatc
    11881 gcaaacagag gaggcgtcac gataaaacga ccatccttta caccatcggc attttccacc
    11941 catgattgaa ttaaataggt gctattttca tcattatttg tcacggcaag ttgcacttgt
    12001 ttttgccctg ccggataaat tacgcgagtc gcacctaagg ccactcccgc ttcagcgcgt
    12061 ccggcaacca tcattgccat gaacatcagg atacctgcca gcaagcagaa tgttatttcc
    12121 tgcgatttcc ttacattgac gtttttatta ctcactgtcc tgttcctgtt atcacattat
    12181 ctgctgaaca attactgata ggttaaagag aaccaggcct gtgcattggc gatgccgcca
    12241 gtaacccgac gcccggtagc acgatatttg gcgatgaaat gtagcgaagt agagcctgag
    12301 taaagccgtt tccagtttgc tggaggacga ttaatcggta cgaggtttcc ttcatcatca
    12361 aacaacgcta cgccaatatt ggtggctatc cctggcccct ctcccacgga aagcacatcc
    12421 ggatttttac catccgcgac accgtgaaac gccacaccca cacgttcact caccaccgtg
    12481 ctacattccc gtaaatgaat aacaaaaggc accggtgcgc tatcttcccc taccgcgtga
    12541 aaccggttac tgctgatttg ccccatattg accgtcattt gtttatcacc agcttcaatc
    12601 cggcaagttt ccgcaataat gacgccctga aattgcatat ttccgccggg cagcgtggta
    12661 ttccatttat ttccggccag agcaaacatt ggcagcaacg acgctaatag aaataatctc
    12721 ttccttttca tcgttatttt tatcacacaa gggtgggcat ccctgcccgt aatgacgtcc
    12781 ctgaacctgg gtaggttatt gatactgaac cttgaaggtc gcatccgcat tagcagcacc
    12841 cggggttgcg gcaccggttg caaaataacg cgcctggaac ggaatggtgt tggttccgtt
    12901 attcagggtt gtttctgaac taaatgtcgc accgtccagc gccagcgcag cacccgttct
    12961 gtccaggatc tgcacaccaa cgtttgttgc gctacccgca gctgaactct gcagagccag
    13021 tacatcagta tgcgtagcat caattgccgt acctaagaag gcaacagcgg cttttgtggc
    13081 aacagtggta tcgcaatcat tcagctgaat gttaaaacca acggcagagc tggttgctcc
    13141 agcctgcttc aggctagcgg tacgaacctg gcctaactga acggtttgat caacagagcc
    13201 tgcatcaact gcgcaagcgg cgttaacaac ttccccttta aagtgaacgg tcccaccatt
    13261 taccgtcgta gtatcggcca gagccgctgc ggaactgagg gacagagccg acagaacaac
    13321 gattgccaga gttttaattt tcatgctgct ttcctttaaa aaactatttc taaatcgaca
    13381 tgggcagtcg ttctgtacac tttgttttgt caacgagttt gactgccaac actgcacagt
    13441 tttcccccaa aagatgaaac atttggggcc aaactgtcca tatcataaat aagttacgta
    13501 tttttctcaa gcataaaaat attaaaaaac gacaaaaagc atctaactgt ttgatatgta
    13561 aattatttct attgtaaatt aatttcacat cacctccgct atatgtaaag ctaacgtttc
    13621 tgtggctcga cgcatcttcc tcattcttct ctccaaaaac cacctcatgc aatataaaca
    13681 tctataaata aagataacaa tagaatatta agccaacaaa taaactgaaa aagtttgtcc
    13741 gcgatgcttt cctctatgag tcaaa
//
LOCUS       DAPOXO010000112        13695 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPOXO010000112 DAPOXO010000000
VERSION     DAPOXO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13695
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.112"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..866)
                     /locus_tag="ROH59_004355"
     CDS             complement(<1..866)
                     /locus_tag="ROH59_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDX4806759.1"
                     /translation="MSDSFTTSELITATQQVFKFNPLFLKLFFRETYTFTSEEVFLDK
                     IPGKVNMAVYCAPMITGKVDRTRGYSTNHFKPGYTKPKHTINPNMSIKRAAGEQIGQP
                     ETPVERRAKIIMQNLLDEELSISQLEEFQAVQAVLYGKYTVSGSNIETYEIDMSRSAT
                     NNVTQSGSTAWSTQDAETYDPSDDIESYADLASGAVNVIIMDGKAWKQLKRFKKFWTA
                     LDTRRGSNSQLEVALKNLGDVVSFKGYYGDTALFVYKGQYLDPVTDTETRYMPDNTMI
                     LGNTKNRGLRTYG"
     gene            complement(925..1254)
                     /locus_tag="ROH59_004356"
     CDS             complement(925..1254)
                     /locus_tag="ROH59_004356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HDX4806760.1"
                     /translation="MTTETYSPDDFILGPDLVVTTVGHFQGGINVPRLTPIMLDATVG
                     TFKVWDGSVGKAIGLTATAVNTGSSSADCSYYKSGSFRYTAINWGTVTDVAKRKSAFA
                     GTPISVG"
     gene            complement(1254..2561)
                     /locus_tag="ROH59_004357"
     CDS             complement(1254..2561)
                     /locus_tag="ROH59_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HDX4806761.1"
                     /translation="MPWNNFPHLAARAFNQPLLLEPTYARVFFSALSDRFGTGRLIDT
                     ASGEVMNSDEMNALAMGWDSSERTRQKSYRVERGIAVLPVTGTLVHKLGYINPVSGMS
                     GYNGIAKRLQQAISDPDVRGVLLDIDSPGGEVAGAFDTADLIARAREQKPVWALASDT
                     ACSAAYLLASACSRRLITQTGTVGSIGVLMAHRCVEKALEIAGVDVTLIYAGAHKVDG
                     NPYSQLPGDVRDEFQLSINSTREQFAQKVSDYTGLKKSRVLATEAAVFIGADAIKSGL
                     ADQLVNYADAIAVMADALKPKMERFMSGTETTAETTTTEQTATTTTIAQVEFNTEQIR
                     ADAASSELARVMAIINCPEAVGREAQAKALAGVPGMTVGQAQVVLAAAPKTAQARTET
                     ALDTLMSTESPATIQDAGSTTATGTTANVSMLVAAGRSILGDE"
     gene            complement(2561..4135)
                     /locus_tag="ROH59_004358"
     CDS             complement(2561..4135)
                     /locus_tag="ROH59_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDX4806762.1"
                     /translation="MTAPQQLLGPDGKTPLRRYAGYNGGGPGFGGQLIDWNAPQQSAD
                     AALLPNFYRGNARADDLVRNNGVASNAVQLHQDHIVGNLFKLSYRPNWRYLGISREDA
                     RALARDVEVAWTEYAEDPHCTIDIERKRTFTMMIREGVATHAFNGETCVQPVWESSAG
                     SVFRTRFKMVSPKRIRNPGYAADTQFRRAGVDIDKNGAAVGYWIAEDTYPLGGVGKCR
                     RIPAQLSSGRHAFIHIFEPLEDGQTRGDNIFYSVMERLKMLDTLQQTQLQSAIVKAMY
                     AATIESELDSQQAFEYIAGAGTDIDSNPLNSFIQSYVTYYNGANIKLGGVKVPHLHPG
                     DKLSLQTAQNADAGFSSLEKSLLRYVAAGVGASYEELSRDYSQVSYSSARASANVSWR
                     FFMGRRRFIAARQASLMFCCWFEEALARGIITLPRSAVRSFYEARNSWTNALWIGAGR
                     MAIDGLKEVQESAMRITTGLSTYQNELALQGQDYEEVMEQQEYEIQRRREMGLSEPSW
                     SVSHPSNTNDNGWGGN"
     gene            complement(4132..4365)
                     /locus_tag="ROH59_004359"
     CDS             complement(4132..4365)
                     /locus_tag="ROH59_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806763.1"
                     /translation="MTSREVLTERLLEAEIALHKLLTGKSTVSLSHGDSAGNNRSYQY
                     SQASIEQLRTYIIELKSQLGLSTGRRRPVGVRL"
     gene            complement(4365..6227)
                     /locus_tag="ROH59_004360"
     CDS             complement(4365..6227)
                     /locus_tag="ROH59_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDX4806764.1"
                     /translation="MTGVEWADKYFYLPEGSSHIAGHWTTQPVQVVMLNMMTNDAIKI
                     VSVRKSARLGYTKILVAALLYFAEHKKRSAVVYQPIDDESDGFVADEVDPAIAEMPVI
                     QKIFPDWDKSNERNNLQRKEMSGAILDFRGASAPGNFRRLTKQVVEGDEVDGWPLEVA
                     KKGKGEGSPIELALVRIKGAAYPKAIFGSTPTVTGKSHIEMLEDAADLTFRFYLTCPH
                     CGEEQVLVFGFDGIEYGLKWDNSLQTNEAKSSSAYYQCCHCPEHFYYRDLEKMEFGGR
                     WIAEDCTWTRDGIHFFDHDGGVVRAPKHAAIVINALYSLNLDGWGEIVSEWLKAKGDP
                     LKEKTFHNTTLGELWSDVASEQLEHDILVNRREKYASQVPDGVVYITGGIDSQTSGRY
                     ECYVWGWGAEEECWLIDKTIVLGRYDEEDTLQRVDGVIRKQYRRSDGTTIGVSRWAWD
                     TGGIDAQVVYNRSLKLGPLWVIPIKGASSYGQPVVNMPRTRNANKVYLSLIGTDTAKD
                     LLAMRLQLEPDSKSATPGAIHFPNDDEIFSTTEAKQLVSEVLIPKLINGRVVYRWDNQ
                     GRRNEALDCWVYGLAALRISKIRFQLNLETLAEQRKKSQNKLSLEEMARMLGGS"
     gene            complement(6214..6780)
                     /locus_tag="ROH59_004361"
     CDS             complement(6214..6780)
                     /locus_tag="ROH59_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806765.1"
                     /translation="MASQAEVAAHLLLSDRRLRDLAKLPGAPVPQGRGDWELDAWRHF
                     YIRYLRSNRRDTTSNDEPEAGDNSPEKNREQWLKNEERQERILMARVKRRILAKRYAP
                     IELISVAVSRVAVELRTRVESWPPRLKKVWPEMPQEASSVLREELAIALNELSDIRID
                     FSDYDVSDIERDLDRVESLARDDTDDGC"
     gene            7149..7394
                     /locus_tag="ROH59_004362"
     CDS             7149..7394
                     /locus_tag="ROH59_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806766.1"
                     /translation="MNREKIEALMSVILKEADPKKFPEKLSEDAIVSFYRANSSYLNC
                     STLREWLSGEAEPSDEILQKIMVQNNWRATKWSNQLP"
     gene            complement(7454..7648)
                     /locus_tag="ROH59_004363"
     CDS             complement(7454..7648)
                     /locus_tag="ROH59_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001727234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806767.1"
                     /translation="MKKLLLAVAFFTLAGCTHSTYTEATRADGSSIKHVMIAPGTKIT
                     TANGGCIDSTGAEASCLGGK"
     gene            complement(7656..8135)
                     /locus_tag="ROH59_004364"
     CDS             complement(7656..8135)
                     /locus_tag="ROH59_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02594 family protein"
                     /protein_id="HDX4806768.1"
                     /translation="MTDPKWLIEARKNLGIREMKGKQHAAEIVQYWKDIKRGGIKDDE
                     TPWCAAFTGAMLERAGIRSTRFESANSYLDWGNELKEPAYGCIAILSRSGGGHVGFVV
                     GKNAAGDLMILGGNQADEVNIKAFPRSRVTGYRWPAGQTDVPQSLPLVNAEKSISEA"
     gene            complement(8135..8407)
                     /locus_tag="ROH59_004365"
     CDS             complement(8135..8407)
                     /locus_tag="ROH59_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000172496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDX4806769.1"
                     /translation="MTLHSVLINANAIICLMLALRLMFFQKTGRYRFFISLTAYLAIL
                     SAAWIALRIFYGKYTQVDPAEFFLNLTICIAVWRARGNISKITGDR"
     gene            complement(8407..8790)
                     /locus_tag="ROH59_004366"
     CDS             complement(8407..8790)
                     /locus_tag="ROH59_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806770.1"
                     /translation="MSEPLTAGVAAGSAGVTFAALFPEATPAVMICALAGAALYVLSS
                     GQHRFWKQVIFALISFVGGVYCAETASAIITGILNAVLSHLNPPVTVKVSPAIGALVA
                     SVISVTSLLRIMSQARLWKSDKGMK"
     gene            complement(8903..9574)
                     /locus_tag="ROH59_004367"
     CDS             complement(8903..9574)
                     /locus_tag="ROH59_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDX4806771.1"
                     /translation="MSNEYLLEYTRIKLRAALRDLSGGSKGQLEALCEHPPADKNAYP
                     RKHIHRVQLEDRTVDALVTPVYALESFSRRRPAPPMSDFEFADSSWRRSVNSLDASQQ
                     AWLRYCYGGNLAFKHQTAICEAVWSRYKGNIPASTQRKVVKRLLSLVWLSVQAVAAAN
                     KREDFKEMAGSTLAGMLSVSRSTWCETYSLHWVGMKEAVRALDEVALLATLHHYQNHL
                     DDVCV"
     gene            complement(9574..9867)
                     /locus_tag="ROH59_004368"
     CDS             complement(9574..9867)
                     /locus_tag="ROH59_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HDX4806772.1"
                     /translation="MKKIDLRKAARSRACTVRIPGVCNHNPETSVLAHYRLAGTCGTA
                     IKPHDMQGAIACSACHDAIDGRTKTDYEHDSLLLMHAEGVFRTLAIWRDEEFI"
     gene            complement(9864..10460)
                     /locus_tag="ROH59_004369"
     CDS             complement(9864..10460)
                     /locus_tag="ROH59_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1367 family protein"
                     /protein_id="HDX4806773.1"
                     /translation="MAQHSFIRVSGGSLIPATPDTQRWLTERVKPGAVVYADFKQARN
                     PAFHRKFFSLLNLGFDYWHPSGGAISPAERELVHGYVKLLAYYGGHGDVMAELADQYL
                     LDESEKRAGSISAVKSFEAFRAWAIMEAGFYDVHQMPDGSLMRVPRSISFAAMDDLEF
                     GQLYSAVLDVLWNYILFRTFASQEAAENAAAQLLDYTS"
     gene            complement(10538..10717)
                     /locus_tag="ROH59_004370"
     CDS             complement(10538..10717)
                     /locus_tag="ROH59_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806774.1"
                     /translation="MNIQESIGELPETCRAVIKRKDGHIVGVRVLTDDERIASLMAFL
                     ELAEIAGYTITPPDA"
     gene            complement(10869..11510)
                     /locus_tag="ROH59_004371"
     CDS             complement(10869..11510)
                     /locus_tag="ROH59_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806775.1"
                     /translation="MKTFYEDWPETFVSRLDMLRALDDRGSTRRLYLERTGAIFDALA
                     EEIRTVVAGHPEIDVSELDIGPLYRYYKRGEKGNPLADLLIELAPPTCERVRISPEVY
                     IIPYLFFALLIAQGADNDARDFFNMMMRPLIIAYRFKQLARYLGTKGGGRPQHRLKSE
                     AIELADRFFTENPTAPLSRGVQYISGIFVAKYSDPPAASTIRKWLIPIYRSDK"
     gene            11754..11987
                     /locus_tag="ROH59_004372"
     CDS             11754..11987
                     /locus_tag="ROH59_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806776.1"
                     /translation="MGTLGNQPCRSRYEFDDFNLANRAAALTKLAKETGVSVDTLIKL
                     EIAMQLNRLNSILIENGDKMDENLAGIGEILQK"
     gene            12386..12874
                     /locus_tag="ROH59_004373"
     CDS             12386..12874
                     /locus_tag="ROH59_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDX4806777.1"
                     /translation="MATNPREHARRVLDTFWCGRGFPVDPAKIAHDMGLDVFITDLPG
                     KVSGALIKQKDQDPAIFLNSDDNKVRQRFSCGHELGHYIARQASHSDEYEYVDLRGET
                     ASAGTHPDEIFANKFAAELLMPVDEVRKLHADGQPSYIMAHYFGVSDDAMTYRLKNLR
                     LG"
     gene            12884..13489
                     /locus_tag="ROH59_004374"
     CDS             12884..13489
                     /locus_tag="ROH59_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806778.1"
                     /translation="MPSDDDFNSRFKQEVARRLKDSLNLHRQLAEEVEPEDDETPVQS
                     PDEASPQPKVSHAPKKTAVRIRGIARKRAAEARKMAVAASSKRIPTATPSQQVTRTES
                     KILTEFTSVKQVNSLDTEHERKQLNNKDFEAEIALKKRYGKWFLIILAFQLLIMNGVF
                     IADGAGKLEFEDLTLQLYMGGTLTEVFGLVLVVTKYLFKRK"
BASE COUNT         3361 a         3612 c         3299 g         3423 t
ORIGIN      
        1 ccataagtgc ggagcccgcg gttttttgtg ttgccaagga tcatcgtgtt atccggcata
       61 taacgcgttt cagtgtctgt taccgggtcg aggtattgcc ctttgtagac aaacagcgca
      121 gtgtcgccgt agtagccttt aaagctgaca acgtcgccca ggtttttcag cgcgacctcg
      181 agctggctgt ttgagccacg gcgcgtatcc agtgccgtcc agaatttttt aaaacgcttc
      241 aactgcttcc aggctttacc atccatgatg atcacgttaa ccgcaccgga ggcgaggtcc
      301 gcgtaggatt caatatcgtc gctcgggtca tacgtttccg cgtcctgagt cgaccaggct
      361 gtcgaaccgg actgagtgac gttattcgtc gcgctgcggc tcatgtcgat ctcataggtc
      421 tcgatattgc tgccggaaac agtgtattta ccgtacagaa cagcctgtac cgcctggaac
      481 tcttcgagct ggctgatgct cagttcctca tcaagcaggt tctgcatgat gatttttgca
      541 cgacgttcga ccggcgtttc cggctggcca atctgctcac cggctgcgcg cttgatgctc
      601 atattcggat tgatcgtgtg cttgggtttc gtgtaacccg gtttgaaatg gttcgttgaa
      661 tagccgcgag tgcggtcaac tttgccggtg atcatcggcg cgcagtacac ggccatgttc
      721 acttttcccg ggattttatc cagaaaaacc tcttcgctcg taaacgtgta ggtctcacgg
      781 aaaaacagct ttaaaaacaa cggattgaac ttaaatacct gctgtgtcgc ggtaatcagt
      841 tctgacgtag taaacgaatc gctcatttat atatcctgtt ataaaaaaac cgcccggagg
      901 cggcttgttt tgagtttttt gctatcagcc gacgctgatc ggcgtacccg caaatgctga
      961 tttgcgttta gctacgtcgg taaccgtacc ccagttaatc gccgtgtaac ggaacgagcc
     1021 tgatttatag tacgagcagt ctgcagaact ggagccagta ttaactgcgg tggcagtgag
     1081 gccaatagct ttaccgactg agccgtccca aaccttaaac gtcccgacag tagcgtcgag
     1141 cataatcggt gtcagccggg gtacgttgat cccgccctga aaatgaccga cggtcgtgac
     1201 aacaaggtca ggcccaagaa taaaatcgtc cgggctatac gtttctgtag tcattattca
     1261 tcccctaaaa ttgaacgccc tgcagcaacc agcatcgaga cgtttgcggt tgttcctgtt
     1321 gccgtagtac tgccagcatc ctgaatagtc gctggtgatt cagtgctcat tagtgtatcg
     1381 agcgccgttt ctgtccgcgc ctgcgccgtt ttaggtgctg cagcgaggac tacctgcgcc
     1441 tgcccgaccg tcatcccggg gacgccagcg agcgcttttg cctgcgcctc gcgcccaaca
     1501 gcttcgggac aattgatgat ggccatcaca cgcgccagtt cgcttgatgc ggcgtccgcg
     1561 cgaatctgct ccgtgttaaa ctcaacctgc gcgatagtag tcgtggtcgc ggtttgttct
     1621 gtggtcgtgg tctccgccgt ggtttctgta ccagacataa agcgctccat ttttggtttc
     1681 agtgcgtcgg ccatcactgc gatagcgtcc gcgtaattaa cgagttgatc agcgagacca
     1741 gatttaatcg cgtccgcgcc gataaatact gcagcttccg tggccagcac cctggatttt
     1801 ttcagcccgg tataatccga gactttttgc gcgaactgct cgcgcgtgct gttaatactc
     1861 agctggaatt cgtcgcgaac gtcgcctggc agctgggaat acgggttccc gtcaactttg
     1921 tgcgcgccgg cgtaaatcag cgtcacgtcg acgccagcaa tctccagcgc tttttcgacg
     1981 cagcggtgag ccatcaggac accgattgaa ccaactgtgc ctgtctgcgt tatcagccgg
     2041 cgcgaacacg ctgacgccag caaataggca gcgctgcagg ccgtatcgct ggccagcgcc
     2101 cacacaggtt tttgctctcg cgcccgggcg attaaatcag cagtatcaaa cgcgccggcg
     2161 acttcaccgc caggggagtc aatatcaagc aggacccctc ttacatcggg atcagaaatc
     2221 gcctgctgca ggcgttttgc gattccgttg taaccgctca tcccgctaac tgggttgata
     2281 taacccaatt tatgaaccag cgtcccggta accggcagaa cggctatacc acgctccacg
     2341 cgatacgatt tctggcgtgt tcgctcgctg ctgtcccacc ccatcgcgag cgcgttcatt
     2401 tcgtcgctgt tcattacctc tccagacgct gtatcaatca gtcgcccggt accgaaccgg
     2461 tcgctcagcg ccgaaaaaaa tacccgcgcg taggtgggct ccagcaaaag cggttgattg
     2521 aacgccctgg cggcgaggtg cggaaaattg ttccacggca tcagttacct ccccagccgt
     2581 tatcgttggt atttgagggg tgagatacag accatgacgg ttcgctcagc cccatttcac
     2641 gccggcgctg aatttcgtat tcctgctgct ccataacctc ctcgtaatcc tgtccctgca
     2701 gcgccagttc gttctgatac gtgctgaggc cagttgtgat gcgcatggcg ctctcctgaa
     2761 cctctttcag cccatcaatc gccatgcgac cagcgccgat ccagagcgcg ttcgtccagg
     2821 agttccgcgc ctcataaaac gaccggacag ctgagcgtgg cagggtgata attccgcgtg
     2881 ccagcgcctc ttcaaaccag cagcagaaca tcagcgacgc ctgtcgcgcg gcgataaaac
     2941 gtcgacgccc catgaaaaat cgccagctga cgttagcact ggcccgggcg ctggagtaac
     3001 tgacctggct gtagtcccgg ctaagttctt cgtatgacgc gccaacgcca gctgcaacgt
     3061 aacgcaggag tgatttttcc agtgaactaa aaccagcatc agcattctga gcggtctgta
     3121 aactgagttt gtcgccggga tgcaggtggg gaactttcac accaccgagc ttgatatttg
     3181 cgccgttgta gtacgtcacg taactctgaa taaacgaatt cagcgggttc gagtcgatat
     3241 cagtacccgc gccggcgata tattcaaacg cctgctggct gtcgagctct gattcgattg
     3301 tcgcggcata catcgccttc acaatggcgc tctgcagttg tgtttgctgc agtgtgtcga
     3361 gcattttcag gcgctccatg acgctgtaaa aaatattgtc cccgcgggtc tgtccgtcct
     3421 cgagcggctc gaatatgtgg atgaatgcgt gtctgccgct gctgagctgt gctgggatac
     3481 gccggcattt accgactccg ccgagagggt aagtatcctc ggctatccag tacccgaccg
     3541 cggccccgtt tttatcgata tcaacaccgg cgcggcgaaa ttgagtgtca gctgcgtaac
     3601 ccggatttcg aatccgtttc ggtgagacca ttttgaatcg cgtccgaaaa acgctgccgg
     3661 cactactctc ccagactggt tgtacgcagg tttcaccgtt gaaagcgtga gtagccacgc
     3721 cctcgcggat catcattgtg aacgtccgtt tccgctcgat atcaatcgtg cagtgagggt
     3781 cctcggcgta ttcagtccac gctacctcga cgtcacgcgc cagcgccctg gcgtcctcgc
     3841 gagatatgcc gaggtaacgc cagttagggc gataactcaa cttaaacaga ttgccgacga
     3901 tatgatcctg gtgcagctgc acggcgttcg acgcgacgcc gttattgcga acgagatcgt
     3961 ctgctcgcgc gttaccgcga taaaaattcg gcaacagtgc tgcgtcggcg ctctgctgtg
     4021 gtgcgttcca gtcaatcagc tggccaccga aaccgggacc gccgccgtta taccccgcgt
     4081 aacggcgtag tggcgtttta ccgtcaggcc cgagcagctg ctgcggagca gtcataatcg
     4141 aactcccacg ggccgacggc gtcccgtact cagaccgagc tgtgatttca gctcgataat
     4201 gtacgttcgg agctgctcaa tactcgcctg cgagtattga tagctccggt tatttcctgc
     4261 tgaatcgccg tgagacagcg acacggtcga tttacccgtt aataatttgt gcagagcgat
     4321 ttccgcttcc agcagtcgtt ctgttaaaac ctcgcgcgac gtcattagct ccctccgagc
     4381 attctggcca tctcctcgag agacagtttg ttttgtgatt ttttccgttg ctcagcgagc
     4441 gtctcgagat tgagctggaa acgaatttta ctgatacgca gcgctgccag tccgtacacc
     4501 cagcagtcga gcgcctcatt tcgccggccc tggttgtccc aacgataaac gacgcgaccg
     4561 ttaatgagtt tcgggatcag aacctcggag acgagctgtt ttgcctctgt cgtgctgaat
     4621 atttcgtcgt cgttgggaaa atgaatcgca cctggtgtcg ccgatttgga gtcgggttcc
     4681 agctgcaggc gcattgcgag caggtctttc gctgtatctg tcccaatcaa cgacaaatac
     4741 actttattcg cgttacgggt acgaggcata tttacgaccg gctggccgta tgagctcgcg
     4801 cccttgattg gaatgaccca cagcggaccg agtttcagcg agcggttata aacgacctgc
     4861 gcatctatac caccggtatc ccacgcccag cgactgacgc cgattgtggt cccgtcgctg
     4921 cgccggtatt gtttgcgaat cactccgtcg acgcgctgca gcgtgtcctc ctcgtcgtag
     4981 cgaccgagga cgattgtttt atcaatcagc cagcactcct cctcggctcc ccagccccac
     5041 acataacact cgtagcgccc ggacgtctga gagtcgatgc cgccggttat ataaacaaca
     5101 ccgtcaggaa cctggctggc gtatttttcc cggcgattaa ccagaatatc gtgctccagc
     5161 tgctcgctgg ccacgtcgct ccagagttcg ccgagcgtcg tgttatgaaa cgtcttttcc
     5221 ttgagcgggt cgcctttcgc tttcagccac tcgctgacaa tctcgcccca tccatcgagg
     5281 tttagtgaat acagggcgtt tatcacgatc gcagcgtgtt tcggcgcgcg aacgacgcca
     5341 ccgtcatgat caaaaaaatg aatgccgtct cgggtccagg tgcagtcctc ggctatccag
     5401 cgccccccga actccatttt ttcgagatcg cgatagtaaa aatgttccgg gcagtggcag
     5461 cactggtaat acgcggacga cgatttcgcc tcattggtct gcaggctgtt atcccatttg
     5521 aggccgtatt cgataccgtc gaaaccaaat accaggacct gctcctcgcc acaatgcgga
     5581 catgtcaggt aaaaacgaaa cgtcagatcg gcagcgtctt cgagcatttc gatatgactt
     5641 ttgccggtaa cggtcggcgt cgaaccaaaa atcgccttcg ggtacgctgc ccctttaatt
     5701 cgaacgagcg ccagttcgat gggcgagccc tcgcctttgc cttttttggc aacttccagc
     5761 ggccagccgt caacttcgtc accctcgaca acctgtttcg ttagtcgccg gaaatttcct
     5821 ggtgcactcg cgccgcgaaa atcaagaatc gcgccgctca tttctttacg ctggagattg
     5881 ttacgctcgt tgcttttatc ccagtcgggg aaaattttct gaatcactgg catttcggcg
     5941 atagcggggt caacctcgtc ggcgacaaat ccatccgatt cgtcatcgat aggctgatag
     6001 accacggcac tacgtttttt gtgctcagcg aaatagagca gcgccgcgac gagtattttt
     6061 gtataaccga gacgagctga tttgcgaaca gacacgattt ttatcgcgtc gttcgtcatc
     6121 atattgagca tcactacctg gaccggctga gtcgtccagt gcccagcgat gtggctggag
     6181 ccctcaggga gataaaaata tttatcagcc cactcaacac ccgtcatcgg tatcgtcacg
     6241 cgcaagggat tcaaccctgt cgagatcgcg ttcgatatcg ctgacatcgt aatcgctgaa
     6301 gtcgattcgt atgtctgaca actcatttaa ggctatcgcc agctcctctc gtaatacact
     6361 gctcgcctct tgcggcatct ccggccagac ctttttcagg cgtggtggcc acgactcgac
     6421 gcgggtacgt aattcaacgg cgacgcgaga tacagcgacg ctaattaatt caattggcgc
     6481 gtagcgttta gcgagaatgc ggcgttttac tcgtgccatc aggattcgct cctgtcgttc
     6541 ctcatttttc agccactgct cgcgattttt ttcgggagaa ttgtcccccg cttccggttc
     6601 gtcattacta gttgtgtcgc gtctattgct ccggagataa cgaatataaa aatggcgcca
     6661 tgcgtctagc tcccaatcac cacgtccttg tgggactggt gctcccggaa gttttgcgag
     6721 atcgcgcaga cgacgatcag atagcagtaa atgtgctgca acctcagcct gacttgccat
     6781 taaaaatcct caccggaacc ggaaataccc aaaatgaaaa aatactaaaa acgagcgagt
     6841 ttttgcgcgt ctaccgaccc tcggtgtttt ggatttcgga aaggacccgc gaccaggggg
     6901 ctatctccct ttcaggacag gaattagggg ctcgcatcag gttcatcaaa ctcaactgta
     6961 gcctcgcggc gtacttgttt gcatacatca gctttgtgta tctgattatc agcgtaagct
     7021 ttcactttgg cagcgagcca tccttttgtg ctgtatcgat agactaccga acaagttttc
     7081 catatatgta tatatcttga acttattgat atcattacag aaaaacaaca accatgagaa
     7141 cgcaaaaaat gaacagagaa aaaattgaag ccttaatgag cgtaatatta aaagaagctg
     7201 acccaaaaaa gtttcctgag aagttatcag aggacgccat cgtatctttt tatcgtgcga
     7261 actcctctta tctaaattgt tcaactttaa gagaatggct aagcggcgaa gcagagcctt
     7321 cagatgagat acttcagaag attatggttc agaacaactg gcgcgcaaca aaatggtcaa
     7381 atcagttacc ttaatctgtt gaatgtgtgc cgccttaaaa caaaaaggcg gcctctcgtt
     7441 aaagtaaatt accctatttt ccaccaaggc atgaagcctc tgccccggtt gaatcaatac
     7501 aaccaccgtt cgcagtagta atcttcgtac ccggcgcgat catcacgtgt ttaatactgc
     7561 tgccgtcagc gcgagtcgct tcggtgtatg tcgaatgtgt gcagcctgcc agcgtgaaga
     7621 acgcgacagc taagagaagt tttttcacgt tttacctacg cttctgagat agatttctca
     7681 gcattcacca atggaagtga ttgtggaaca tccgtttgac ctgctggcca gcggtagcct
     7741 gttacgcggg aacgaggaaa agctttgata tttacttcat ctgcctggtt gccccccaaa
     7801 atcattaaat ccccggcggc atttttcccg acaacaaagc cgacgtgacc accgccagac
     7861 cgagacagaa tagcaatgca tccataggcg ggttccttca gttcattacc ccaatcgaga
     7921 taagaattcg cagactcaaa acgcgttgag cgaatacccg cacgttccag cattgccccg
     7981 gtgaaagcag cgcaccacgg tgtttcgtca tccttaatgc cgccgcgttt gatatctttc
     8041 cagtactgca caatttctgc agcatgttgc ttccctttca tttcccgaat gccgaggttt
     8101 tttcgagcct cgattagcca tttaggatcc gtcattacct gtctcctgtt atttttgaaa
     8161 tattccctcg tgcccgccag acagcaatac agatggtgag gttgagaaag aactctgcgg
     8221 gatcaacctg cgtatatttc ccgtaaaaaa ttcgtagggc tatccacgca gcagacagaa
     8281 tcgcgaggta agcagttagt gagatgaaaa aacgatagcg gcctgttttt tgaaaaaaca
     8341 tcaaccgtag tgccaacatc agacaaataa ttgcattggc attgatgagg acagagtgca
     8401 gggtcattat ttcatcccct tatctgattt ccataaacga gcttgtgaca tgatccgcaa
     8461 cagtgatgta acgctgatta ctgatgcaac cagtgcacca atggcgggag agacttttac
     8521 tgttacggga gggttcaggt gactcagcac cgcgttcaga ataccggtaa tgatggctga
     8581 cgctgtctca gcgcaataca caccgccaac aaacgaaatg agtgcgaaaa taacctgctt
     8641 ccagaatcga tgctgcccgg acgacaacac atagagagct gcgcctgcca gcgcacagat
     8701 catcactgca ggtgttgcct caggaaataa cgcagcaaac gtcacccccg ccgagccagc
     8761 agcaacgcca gcggttagag gttcagacat gatttttcct gattcagaaa cgacaaaacc
     8821 ccgccgtggc gaggttctta gaaatttggc aacataccaa attagcgtca aatatggcct
     8881 attttgttcg tttttgcaag cattatacgc aaacgtcgtc taaatggttc tgataatgat
     8941 gcaaagttgc aagaagtgcc acttcatcaa gtgctctcac cgcctctttc attcctaccc
     9001 agtgcaggga gtatgtttcg caccaggtgg aacgagaaac cgacagcatt cctgctaggg
     9061 tagatccggc catctcctta aaatcctcgc gtttatttgc tgctgcgacc gcctgcacgg
     9121 acaaccacac caacgaaagc aggcgcttaa ctacttttct ctgagttgac gcggggatgt
     9181 ttcctttata gcgactccag acagcctcac aaatagctgt ttggtgtttg aatgccaggt
     9241 taccaccgta gcaataacgc aaccacgctt gctgacttgc atccagcgag ttcacagaac
     9301 gccgccagga tgaatcagca aattcaaaat cactcatcgg cggcgcgggg cgacgtctgc
     9361 tgaaactttc cagagcgtaa actggcgtaa ccagagcatc aacggtccgg tcctccagct
     9421 gcacacggtg aatatgtttg cgtgggtatg cgtttttgtc tgccggtggg tgctcacaca
     9481 atgcttccag ttgcccctta gaaccaccag acaaatcccg caatgcagcg cgcagtttta
     9541 tgcgggtata ttccaataaa tactcgttac tcatcagata aactcctcat cgcgccagat
     9601 agccagtgtt ctgaaaactc cctcagcgtg catcaacaac aatgagtcgt gctcgtaatc
     9661 cgtttttgta cgtccgtcga tggcatcgtg acacgcactg caggcgatag cgccctgcat
     9721 atcgtgaggt ttgatggctg tgccgcacgt tccggcgaga cgataatgag ccagtacgct
     9781 ggtttcagga ttgtgattgc acacaccggg gatacgcaca gtacaagcgc gactgcgtgc
     9841 agcttttctc aggtcgattt ttttcatgat gtgtaatcca gcagctgcgc ggcggcattt
     9901 tcagcggcct cctgagaggc aaatgtgcgg aacaaaatat aattccacag cacatctaaa
     9961 acggctgaat acagttgacc gaactcaaga tcgtccatcg ctgcaaacga gattgaacga
    10021 ggtacgcgca tcaaactgcc gtctggcatc tgatgaacgt cataaaaccc agcttccata
    10081 atcgcccatg cgcgaaacgc ctcgaacgac ttcaccgcac tgatactccc cgcgcgcttt
    10141 tccgactcat cgagaagata ctgatcagcc agctctgcca tgacatcacc gtgtccaccg
    10201 taatacgcca gtaacttaac gtagccgtga accagttcgc gctccgcagg agaaatagcc
    10261 cctccggacg gatgccagta atcaaagccc aggttgagaa gtgagaaaaa tttacgatga
    10321 aacgcgggat tacgcgcctg tttgaaatct gcatacacaa cagcacctgg tttgactcgt
    10381 tcagtcaacc agcgttgcgt gtctggtgtc gcgggtatta gcgaaccgcc ggataccctg
    10441 ataaatgaat gctgcgccat ggttaactcc aggtggcgcg gcagtgttca gaaaatggtg
    10501 ccgggtgttc aatccagcac cgatattata ccgtgtttta cgcgtcaggg ggtgtaatag
    10561 tatatccagc tatttctgcc aactcgagaa acgccatcag gctggcaatc cgctcatcat
    10621 cggtcagaac acgcacacca acgatgtgtc cgtccttacg cttgataaca gcccggcatg
    10681 tttccggtag ttcgcctata gattcttgaa tattcatgtc ttccccccaa tgccacaacc
    10741 tgtatattta tacagtattt tatggcattt gtcataacgc caaatacaat gagggaataa
    10801 tgaacaatta tattcacgtc gtgaatttta ttaaacggtt ttatagggga ttaaaccgtt
    10861 tatggtcatt atttatcact cctgtaaatt ggaattaacc attttctaat cgtcgacgct
    10921 gcaggtgggt cagagtattt cgccacaaaa ataccggata tgtattgcac gccacgcgat
    10981 aatggcgctg tcgggttttc agtaaaaaaa cgatcagcca gttcaatggc ttcgcttttt
    11041 aatctgtgct gtggtcgtcc tccgcccttt gttcccaggt atcgcgccag ttgtttgaaa
    11101 cggtaggcga tgattaacgg tcgcatcatc atattgaaaa aatcgcgggc atcgttgtca
    11161 gcgccttgcg ctatcaacag tgcaaaaaac agatacggga ttatgtacac ttcaggagat
    11221 atacgaaccc gttcacaagt tggtggagcc aactcaataa gtaagtcagc cagcggattc
    11281 cccttttctc cacgtttgta atagcgatac agcggcccga tatcaagttc actcacgtcg
    11341 atttcaggat gcccggcaac gactgtacgt atctcttctg ccagagcgtc aaatattgcc
    11401 ccggtccgtt caagatagag cctccgggtc gaaccgcgat catccaacgc ccgtaacata
    11461 tctaaccggc taacgaaagt ttcaggccag tcctcataga aggttttcat aattacctcg
    11521 aataataaaa actgcactat ttgcacaatt tattattcgt tttcacgccg ctgagttcta
    11581 taaaaaagaa aaaacctccg aggcagggtt ttgttatggc tcgttaaatc atcatccaac
    11641 tttttagact gaacggtgat acttgcaaat atttgaaaat atgggctgga accctatctt
    11701 atgatgtgcc tggtaattta tattgttggg tctttatatc atgaggaatc actatgggta
    11761 cgttaggcaa ccagccgtgc agaagtcgtt atgagttcga tgattttaat ttagccaatc
    11821 gagctgcggc tcttactaag ttagcaaaag aaactggtgt atcggtggat accttaatca
    11881 aacttgaaat tgctatgcaa ctgaatcggc tcaactccat ccttatcgaa aacggtgaca
    11941 agatggacga gaatctggca ggtattggcg agatactgca gaagtgagag tagcccctct
    12001 tctgaggggt tgcacattta aaatattaag ggcggtcttc ttcacgtaca cagtcacctg
    12061 gtcgaatcgt tcacgcatac tgagtacaaa aaatctcaac gataagatca ggttagacct
    12121 gtattttcca gaaacatata gacgcctaaa aaaacactaa actcatgatt atcatgtatg
    12181 tttttactgg aaacattgaa ccatccacaa tacagcgtaa aaagcaagca attcacaaga
    12241 ttttaaagtg atttatctgg aagactttac tactaacagt taatatcgta ccagaagtgc
    12301 agaatttgca cttttacagg aatgtggtac ggaacatgct gtctatattt caaccaataa
    12361 tcgtaatgca gtaactggag gagctatggc taccaaccca agagagcacg cccggcgagt
    12421 gctggacacg ttctggtgcg ggcgtggttt ccctgttgat ccagcgaaaa ttgctcacga
    12481 catgggatta gatgttttta ttaccgatct tcctgggaaa gtttctggcg cactgattaa
    12541 acaaaaagat caagatccag cgatctttct aaacagtgat gacaacaaag ttcgtcaacg
    12601 tttttcatgt gggcatgagt tggggcatta catcgcccgg caagcatcgc atagcgatga
    12661 atatgagtac gttgatttac gtggcgaaac cgcaagcgcc ggaacgcatc ctgatgaaat
    12721 ttttgcaaac aagttcgcag cagaacttct gatgccggta gatgaggtca gaaaactgca
    12781 cgctgacggt caaccaagtt atataatggc gcattatttt ggcgtatctg acgatgcgat
    12841 gacttatcgt ttaaagaact tgaggttggg gtaacgcttt aaaatgccat cggatgacga
    12901 ttttaacagc cgtttcaaac aggaagtagc acgcagactg aaggattccc tcaacctaca
    12961 ccgtcagtta gcagaagagg ttgagccgga ggacgatgaa actccggttc agtctcctga
    13021 cgaagcttca cctcagccaa aggtttcgca cgcccccaaa aaaacggctg tccgtattcg
    13081 cggaatagcc agaaaaagag ctgccgaagc tcgcaaaatg gctgtagctg cgtctagcaa
    13141 aagaattcca actgctacac cctctcaaca agtcacccgt actgagagta aaatcttgac
    13201 cgagttcaca tctgtgaaac aggtgaattc acttgatacc gagcatgagc gcaaacaact
    13261 caacaacaaa gattttgaag cagaaatcgc tctaaaaaaa cgatacggga aatggttcct
    13321 gattatcctt gctttccaac ttctgataat gaatggtgta tttattgccg acggcgcagg
    13381 taagctggaa tttgaggatt taacactaca gttgtacatg ggcggtactt tgacagaggt
    13441 attcggcctc gtgctggtcg tgacaaaata cctttttaaa cgcaagtaac tctctcggtc
    13501 caacagtctt tcgaaggccc tgatcaaagg gccttgataa attagcagtg cgttgaaaac
    13561 agatagttat tcccatcagt tccaacgtaa tacacatcaa aaaaatcacc attcttttgc
    13621 tctaacgtca acacctaccc ttaaaaaaat aattctccaa gaatgagaaa gttattgtgt
    13681 gtattagata agata
//
LOCUS       DAPOXO010000113        13606 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPOXO010000113 DAPOXO010000000
VERSION     DAPOXO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13606
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.113"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            122..1045
                     /locus_tag="ROH59_004375"
     CDS             122..1045
                     /locus_tag="ROH59_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX4806779.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLIGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISMDSRRRARKINRPARHE"
     gene            complement(1049..1867)
                     /gene="nlpA"
                     /locus_tag="ROH59_004376"
     CDS             complement(1049..1867)
                     /gene="nlpA"
                     /locus_tag="ROH59_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HDX4806780.1"
                     /translation="MKLTTHHLRAGAALLLAGVLLAGCDQSSSDEKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVNDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW"
     gene            2089..2382
                     /locus_tag="ROH59_004377"
     CDS             2089..2382
                     /locus_tag="ROH59_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806781.1"
                     /translation="MKPTMLLMITIFLIFPAISQAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDESNKQHIREAIVAMERNNQSNYWEALGKVECPDM"
     gene            complement(2423..3613)
                     /gene="nepI"
                     /locus_tag="ROH59_004378"
     CDS             complement(2423..3613)
                     /gene="nepI"
                     /locus_tag="ROH59_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HDX4806782.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFVGTSLSSFIL
                     KRSVKLALAGAPFVLALSALVLTLWGSDKIVATGVAIIWGLTFALIPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MKKS"
     gene            3847..4200
                     /locus_tag="ROH59_004379"
     CDS             3847..4200
                     /locus_tag="ROH59_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDX4806783.1"
                     /translation="MFKTKWFAREARSHAITDEELCRAILETEQGKADVLGGGVFKKR
                     LHRNRERAIILAKGGSNWFYTFLYAKQDMSNINSQELAGFRELAKHYAFLTKAQLTAM
                     INTKELTEICYDCKN"
     gene            4184..4507
                     /locus_tag="ROH59_004380"
     CDS             4184..4507
                     /locus_tag="ROH59_004380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HDX4806784.1"
                     /translation="MTAKTKFKSPAFEAIHSAAAGLSRVDAISAETMRTFDKACLTSV
                     QDLQPVEIKALREKLKVSQPVFAHYLNTSVSTVQKWESGAKRPNGISLKLLSIVQKHG
                     LEVLL"
     gene            complement(4623..5075)
                     /locus_tag="ROH59_004381"
     CDS             complement(4623..5075)
                     /locus_tag="ROH59_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HDX4806785.1"
                     /translation="MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            complement(5128..6462)
                     /gene="adeQ"
                     /locus_tag="ROH59_004382"
                     /gene_synonym="yicO"
     CDS             complement(5128..6462)
                     /gene="adeQ"
                     /locus_tag="ROH59_004382"
                     /gene_synonym="yicO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeQ"
                     /protein_id="HDX4806786.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGVFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALSLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDSNGKFPNMNKALYVDSISSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTA
                     VVVGVMFLLVMFFSPLVAMVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITT
                     VMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD"
     gene            6637..8403
                     /gene="adeD"
                     /locus_tag="ROH59_004383"
     CDS             6637..8403
                     /gene="adeD"
                     /locus_tag="ROH59_004383"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDX4806787.1"
                     /translation="MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLIN
                     GGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVT
                     FETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
                     VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGL
                     GGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNS
                     PQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGL
                     LAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIDRQP
                     VSASDFALQFTPGKRYRVIEVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRL
                     APACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNG
                     QVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPAL
                     KLTSQGLFDGEKFAFTTLEVTE"
     gene            complement(8450..9841)
                     /gene="uhpT"
                     /locus_tag="ROH59_004384"
     CDS             complement(8450..9841)
                     /gene="uhpT"
                     /locus_tag="ROH59_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HDX4806788.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNQYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(9979..11298)
                     /gene="uhpC"
                     /locus_tag="ROH59_004385"
     CDS             complement(9979..11298)
                     /gene="uhpC"
                     /locus_tag="ROH59_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HDX4806789.1"
                     /translation="MLPFLKAPADAPLMTDKHEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNSAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAASALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVIAIAAGISALLLLPFLNAQTPREA"
     gene            complement(11308..12810)
                     /gene="uhpB"
                     /locus_tag="ROH59_004386"
     CDS             complement(11308..12810)
                     /gene="uhpB"
                     /locus_tag="ROH59_004386"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HDX4806790.1"
                     /translation="MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLMQAVGLTHFSLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQHDERLMLVIE
                     DDGSGLPPDSGQHGFGLTGMRERVTALGGTLTISCLHGTRVSVSLPQRYV"
     gene            complement(12810..13400)
                     /gene="uhpA"
                     /locus_tag="ROH59_004387"
     CDS             complement(12810..13400)
                     /gene="uhpA"
                     /locus_tag="ROH59_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HDX4806791.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
BASE COUNT         3658 a         3650 c         3297 g         3001 t
ORIGIN      
        1 tatatgtcat tatttcctcc attcactaaa actgattgat tactctactc cctcaccgtc
       61 atcggtagtg gtatccttaa cgtatattga tgaaaagaca aaacagtatg cagagggaaa
      121 aatgggttcc accagaaagg ggatgctgaa cgttctgatt gccgccgtgt tgtggggaag
      181 ttcaggggtc tgcgcgcaat acatcatgga gcaaagccag atgtcgtcgc agtttttgac
      241 tatgacgcgt ttgatattcg ccggattgat tctgctgacg ctatcatttg ttcatggtga
      301 taaaatcttt tctattatta acaatcacaa agatgccatt agcctactga ttttttccgt
      361 ggttggcgcg ctaaccgtac agctcacttt tttgctaacc atcgaaaaat cgaacgcagc
      421 cacggcaacg gtgctgcaat tcctctcacc gactattatc gtcgcctggt tctcactggt
      481 gcgtaaatcc cgccccggca tcctggtttt ttgcgctatt ttgacatcgc tgatcgggac
      541 ttttttattg gtgacacacg gtaatccgac gtcattatcg atctctcctg ccgcgttatt
      601 ctggggcatt gcctcggcat ttgctgctgc attctatacc acctatccct caacgctgat
      661 tgctcgctat ggcacgttac cggtcgtcgg ctggagtatg ctcattggcg gtctgatcct
      721 gctgcccttt tatgccagac aagggacaaa ctttgtcgtt aacggcagtt tgattctggc
      781 gtttttttat ttggtggtca ttggtacgtc cctgacattt agtctgtacc tgaaaggagc
      841 acaattaatt ggtggtccaa aagccagcat tttaagctgt gcagaaccat taagtagcgc
      901 actgctctct ttgctgttgc tggggatcac cttcacattg ccggactggc tgggaacgct
      961 gctgattctg tcatcggtga ttttgatttc aatggattcc cgccgccgcg ccagaaaaat
     1021 aaatcgtccg gcgcggcatg agtgagaatt accagccagg caccgcgcct ccgttaaaga
     1081 tggtttctgc cgctttagcg acttcgggtg attgataaga ttgcagaaat tccttcacgt
     1141 tttctgcatt cttattatct tcccgtgcca ccagaatatt cacatacggc gaatttttat
     1201 cttcaataaa tacgctgtcg ttaaccggag aaagtcctgt ttgctggatg taagtggtgc
     1261 tgataatcgc tacatccact ttcgggtcgt ccagtacacg tggcaactgt gccccttcca
     1321 gctccattat ctgcaaatgg cgtggattat cggttatatc caacgcggta ggtaataacc
     1381 cttttccctc tttcagagta attagcttct ctttttgcag cagtaaaagc gcacgaccaa
     1441 ggttagtcgg gtcgttgggg atcgccactg tcgcgccttc ttttatttgc gccacggttt
     1501 tgattttttt ggaataaccc gccatgggga agacaaacgt atttcccacc gctaccagtt
     1561 tataaccatg cgcctgatta tcttgttcaa gaaagggtcg atgctggaag acgttcgcat
     1621 caagctcgcc atgatttgtc gcatcgttcg gtagcaacga accgctaaat cctaccagtt
     1681 caacatcgag gccatatttc tcttttgcta cctttttagc gacttccgcg acatcttgtt
     1741 ctgcgccatt aataacgcca actttaatat gcttttcatc gctactgctc tggtcgcaac
     1801 ctgccagcag aactcctgcc agtaataatg cggcccccgc ccgtagatga tgtgttgtca
     1861 gtttcatttt tttatccttt tattaatgat tacctgacta tagcggtaag gtcgctgcag
     1921 tttaaaaaac gaaacgctat cgataagaat aaaaaggaat aaaagtggaa tataaagtct
     1981 ggcacttctt actgaccacg caaacacctt tcgtacagca tgatgagagc ggcaaaagca
     2041 aactacactt atgcttcatt cgatgcacat ttgcagaagg ttgccgctat gaagccaacg
     2101 atgctactca tgattaccat attcctgatt tttccagcca tttctcaggc cgagtcgcca
     2161 ttcagttccc tacagtcggc aaaagagaaa accacggtat tgcaagattt acgtaaaatt
     2221 tgtaccccgc aggcatcgtt atcagatgaa gcgtgggaaa agttaatgtt gtctgatgaa
     2281 agcaataaac aacacatacg cgaagccatc gtagcgatgg aacgtaataa tcagagcaat
     2341 tattgggaag cgttgggtaa ggtagaatgc ccggatatgt aagaacggca acaaccactg
     2401 accaacgctt ctttacctga tatcaggatt tcttcatttt cacctttgca gtcaccaaca
     2461 atgcagtcag caacatcaat gtgccggaca acatcagcgg cgaagtcaga ccaatgttat
     2521 ccaacgcata accgccgatt gccgcaccgc aggtattggc aagctgaata acggccacct
     2581 gaatagatcc ggctttttct gcctgatcgg ccagtgagcg agtgatccac gttgaccagc
     2641 caacgggaat taaagcaaag gtcagccccc agataatcgc cacaccagta gcaacaattt
     2701 tatcgcttcc ccacagcgtc agtaccagcg cgctcagggc gagcacaaac ggtgcgcccg
     2761 ctaaggccag tttcaccgaa cgtttgagaa taaacgacga aagcgatgtc ccgacaaagc
     2821 tggcgatacc aaaactcagc agcaccaggg ttaagccatc aacaccgaat cccgccagat
     2881 tcatatacac tgggcgaata taagtgaaaa aagcaaactg tccggcaaag gacataaaga
     2941 tggcgatcat cccggccatc actcccggac gttgtaataa gcggaaagta ttttgtttct
     3001 gatgcgaagg ttcgcctggc agcgaaggca gtgatttgat aatccagaaa atacacagca
     3061 cgcccatcac cgccgccgca ttaaagacat tgcgccaacc gataagctcg cctaaaaaac
     3121 tgcccaacgg cgcggcaatc accagcgcaa tagaaaccgc gccgaagatc accgacagcg
     3181 ccttcggcac cgtacgcggc ggtaccagac gcatggtcag cgacgccgac atcgcccaga
     3241 atccgcccag cgccagcccc agacaggcgc gaccgattaa caacagactg aatgagttgg
     3301 caaaggaaac cagcaaacag gaaagcgtca gcaaaacggc gaacagaatg acaacgtagc
     3361 ggcggtcagt ggcctgaatg gtctgggtaa taaacaaact ggcaaacatc gccacaaaag
     3421 cggttacggt caccgattgc ccggcaaccc cttccgaaat gcctaaatcc tgggccattg
     3481 gcgtcaacaa actgacgggc aaaaactcaa cgataataag acaggcaacg caaaatgcca
     3541 ccgagaaaac ggctgaccag ttcggtcggg tgatggcatc cgcgccgcgg ttttcagcaa
     3601 taaattcact catggtgtta cccgtggcat gtttcagagg gaaagccgac cactttaaca
     3661 ttgaaatgtg tgacgtattt aacgtttttg caacttttac ggtgttgtgg gaaaagttcg
     3721 aggctgctcg aagaaataaa aatcataggg caaggtgata tgcattttcg cgattaggtt
     3781 gggaataagg gataaagtat tgcacttggt gatatacttt aataacagga tctcaacgat
     3841 atgcgcgtgt ttaaaaccaa atggtttgca agggaagcca ggtctcatgc aataacagat
     3901 gaagagttgt gccgggccat tttagaaacg gaacaaggta aagctgatgt acttggtggt
     3961 ggcgttttta aaaagcgcct tcaccgaaat cgtgagcgtg caattattct ggcgaaaggg
     4021 ggaagcaatt ggttttacac gtttttatat gcaaaacagg atatgtcgaa cattaatagt
     4081 caggaactgg ctgggtttcg tgaacttgca aagcattatg ccttcctgac gaaagcccaa
     4141 ctgacagcaa tgattaacac taaagaactg acagagatct gctatgactg caaaaactaa
     4201 atttaaaagt cctgcatttg aagctattca cagcgcagcg gctggattgt ccagagtcga
     4261 tgctatttct gccgaaacga tgcgtacttt tgacaaagcc tgcctgacca gcgtgcaaga
     4321 cttacaacct gttgagataa aagcactgcg ggaaaaatta aaagtgagtc agcccgtctt
     4381 cgctcactat ctcaatacca gcgtttcaac tgtacaaaaa tgggaaagtg gcgctaaacg
     4441 ccccaatggc atttcattaa aactgctcag cattgtgcaa aaacacgggc tggaggtgct
     4501 gctgtaaata gaacgtagat aatgcgttca cctactgtca attccgatac cggatgcgac
     4561 gtacacgcct tatccaccca ccaggtcagg cgcggtctgt aggctgataa gacgaagcgg
     4621 ttttaatgca gccagtgaac gccctcggca ggctgaaaga acgcgttata gcgcatctga
     4681 aaagcattga tatcctgcat ttcaggttcg gtttcgcgca gaaaacccag cgccagtctg
     4741 acctgagcat cggtaatcgg cgcggcaagg cgggcttttt gtaaaatccg atgccattgc
     4801 agcaggttct gttcgctacc atcgacaatg acaatttgcc agatgagcaa cacctgcgcg
     4861 gcgttttgca ggtgcgactc atccgggcga tgcaaataac gtaaaaattc gtcaccggct
     4921 gactttccca tttgatcgac catcgactcc acgggtacga catcgatgtt cagccgatcg
     4981 ctgagacggc gaatcgcttt tctggccccg gatgtcagca cccgaaaacc aaccacaaac
     5041 actaccgcca gcgtggcgag cattatccag atcatgagtt ctcctgcgta atcagaactc
     5101 atgatatctg gaaaccctcg ccagttacta atccaccaga ataatcttca gtgcaaacag
     5161 agctgcgacc accaccacac acaggttcag atcgcgccag cgcccggtgc acactttcat
     5221 gatgcagtac gacataaagc ctagtgcaat cccttcggtg atcgagaacg taaagggcat
     5281 catcaccgtg gtaataaacg caggcaccga ttcggtaaaa tcatcccagt taacgcgtgc
     5341 caggctcgat gtcatcaata cgccaacaaa gattaacgct ccggcggttg cgtaaggagg
     5401 aaccatcgcc accagcggtg agaagaacat aaccagcaga aacataacgc cgacaacaac
     5461 cgcagtcagc cccgtgcgac caccgacagc cacacctgaa gtactttcaa tataggcggt
     5521 aacagacgag gtaccgataa acgcacccgc caccgaactg atgctatcaa catacagcgc
     5581 cttattcata ttggggaatt taccgttact atctattaag ccagctttat cagtcacacc
     5641 aattaatgtc cctgatgaat caaataagtt gatcagcata aaggagaaaa tgataccggc
     5701 gagttcaagt gataacgcac cgctcaaatc cacttcacca atgacgccgc taatatcagg
     5761 cggaatggaa tagacaccgc taaaatgaac atcaccgaaa aataatccac agcaagacgt
     5821 caccacaata gaaacaagca ccgcggcatg aaaatgacgt gatgacaaca cagttataat
     5881 aaaaaaccct aaaataccta acaacacgcc gtgagaactt aaatcgccaa tcatcaccag
     5941 ggtgtcttta ttggcgacaa taacgccagt attttttaat cccattaagg cgataaataa
     6001 tccgattccg ctggtgatac caatacgtaa acttaatgga atgttggaga tcatccagta
     6061 ccggatacga aacagcgtga gcaaaaatag cccaactgcg ccccagaata tcgcgcccat
     6121 cccggtctgc caggagatac ccatcgcccc cacgaccacg aaggcaaaga aggcgttcag
     6181 gcccattgcc ggagccagtg ccacgggtaa gttagcaaat acccccatcg caatactgcc
     6241 gataccggca atcaaacagg tggtaacaaa caccactttt gggtccattt gtgccgcgcc
     6301 gaggatttgc gggttcacaa aaacgatgta caccatggtt aaaaaagtgg tcatccccgc
     6361 aatcaattct gtgcggacgg tggtcccatg ctgaggtagt ttaaataatc gcgaaagcgt
     6421 ccctgattca ttactcacgt aatcggtatt gtcattattc atttttttgt ccattggagg
     6481 agatttaatc ccttgctttt gtaaaacaaa tgacaacaac ggttcagtga taattatcac
     6541 atttcaattg cacattaatg gatattcttt aataatctcg cgacgtttct ttatgataaa
     6601 taataatcaa attgataaaa tcaaaatgag aaaaatatga ataattctat taaccataaa
     6661 tttcatcaca ttagccgggc tgaataccag gaattgttag ccgtttcccg tggagacgct
     6721 gttgccgatt atattattga taatgtctct attctcgacc tgatcaatgg cggagaaatt
     6781 tccggcccaa ttgtgattaa aggacgttac attgccggtg ttggcgcaga atacgctgat
     6841 gctccggctt tgcagcggat tgatgcccgc ggcgcaacgg cggtgccagg gtttattgat
     6901 gctcacctgc atattgaatc cagcatgatg acgccggtca cctttgaaac tgctaccctg
     6961 ccgcgcggcc tgacgaccgt tatttgcgac cctcatgaaa tcgtcaacgt gatgggagaa
     7021 gccggattcg cctggtttgc ccgctgtgcc gaacaggcaa ggcaaaacca gtacttacag
     7081 gtcagctctt gcgtacccgc cctggaaggc tgcgatgtta atggtgccag ttttaccctt
     7141 gaacagatgc tcgcctggcg ggaccatccg caggttaccg gccttgcaga aatgatggac
     7201 taccctggcg taattagcgg gcagaatgcg ctgctcgata aactggacgc atttcgccac
     7261 ctgacactgg acggtcactg cccgggtttg ggtggtaaag aacttaacgc ctatattgct
     7321 gcgggtattg aaaactgcca cgaaagttat cagttggaag aaggacgccg gaaattgcaa
     7381 ctcggcatgt cattgatgat ccgtgaaggg tccgcagccc gcaatctcaa cgcgctggca
     7441 ccgttgatca acgaatttaa cagcccgcaa tgcatgctct gtaccgatga ccgtaacccg
     7501 tgggagatcg cccatgaagg acacatcgat gccttaattc gccgcctgat cgaacaacac
     7561 aatgtaccgc tgcatgtggc atatcgcgta gccagctggt cgacggcgcg ccattttggt
     7621 ctgaatcacc tcggcttact ggcacccggc aagcaggccg atatcgtcct gttgagcgat
     7681 gcgcgtaagg tcacggtgca gcaggtactg gtgaaaggcg agccgatcga tgcacaaacc
     7741 ttacaggcgg aagagtcggc gagactggca caatccgccc cgccatatgg caataccatt
     7801 gatcgccagc cagtttccgc cagtgacttt gccctgcaat ttacccccgg aaaacgctat
     7861 cgcgttattg aggtaatcca taacgaactg atcacgcact cccgctccag cgtctacagc
     7921 gaaaacggtt ttgatcgcga tgatgtgtgc tttattgccg ttcttgagcg ttacggacaa
     7981 cgactggctc cggcctgtgg tttgctcggc ggctttggcc tgaatgaagg tgcgctggcg
     8041 gcgacggtca gccatgacag ccataatatt gtggtgatcg gtcgtagcgc agaagagatg
     8101 gcgctggcgg tcaatcaggt gattcaggat ggcggcgggc tgtgcgtggt ccgtaacggc
     8161 caggtacaaa gtcatctacc gttgcccatt gccgggctaa tgagcaccga cacggcgcag
     8221 tcactggcgg agcaaattga cgccttgaaa gccgccgccc gtgaatgcgg tccgttaccg
     8281 gatgagccgt ttattcagat ggcgtttctt tccctgccag tgatccccgc gctgaaacta
     8341 accagtcagg ggctgtttga tggtgagaag tttgccttca ctacgctgga agtcacggaa
     8401 taataaaaaa aagcccggcg tcatgccggg caaaagtcac cagttacgtt tatgccactg
     8461 tcaactgctg aatttttttc tcgcggcgga ttttgcgttc ttccatcacc gccactatcg
     8521 ccatcaggca gatacaacca atcgcggcga tatccagcgc ggcgaaggtg cctgcccagc
     8581 cggtaaggcc aaataccggc gtcccatcgg caatcattcc cagacctaac ttggcaaagc
     8641 tgtcaccaat caggtaagcg aaggtgcctt taataccatc ggcagcgcca atcgcttttt
     8701 taggtacaaa gccaacagcc gccacgccaa tcaacagttg cgggccaaag accaggaaac
     8761 ccaacgcaaa gagagaagcc aggtagatat attggttgct ggcgtgttga tacacaccga
     8821 gcgtggcgat aatcagcgcc agcgcgatac aggccaccag gccacggcga ccgttcgcca
     8881 ggtcagagag ccagccccac agcagcgtac cgaccagcgc accagcttca aacagcgtaa
     8941 agccctgaat cgccaccgct ttagagagtt tcagttcctg gaacgcatac acagttgacc
     9001 actggtcgat accaatacgc accacataga ggaaaatgtt ggcgaagcac agcagccaga
     9061 tcactttgtt tttcagcaca tactcaacaa agatctgcca cttggtcata tcggtagatt
     9121 ctgtctcttt atcctcttca ctgatctcct cgccaaacag ctcttcagct ttgccgaggc
     9181 cataagattc cggggagtcg ctgccgtaac gcagaccgat aaaaccaaca atcagcgcga
     9241 taatcgacgg gaaaataaac atgccgatga catgaccatc gaacaggtaa tttgcgccga
     9301 acagcgccac acctgctgcg cctgcaccac caaggttgtg agaaatgttc cagaaaccga
     9361 ggaatgtccc gcgtttacga cgcggcgtcc atttggtgat ggtggagtaa ctgcatgaac
     9421 cgccggtact ctggaaaaag ccgctcaagg cgtagaaggc aatcatcagg aacaggctaa
     9481 ccgagccgct gcccatactg gcactgaagc ccagcataca aatggcagac aggatcagca
     9541 tgaacggcag gaattgtttg gtgtttttgc cgtcggcgta gtaagaaacc agcgttttac
     9601 ccacgccata agtgatggag aagcccaggc cgatcatccc cagctgcgtc atgctcaacc
     9661 cgtaggtcga gatcatgtcg ttctgcgcga tgttaaagtt cttgcgaatc aggtacatcg
     9721 taaggtagcc gataaagacc accaggtagg attgcatgaa cggtttgaac cacattttgc
     9781 gccgcacttc gagcggaagg tccagggtcg gcttgcgaac ctggtttaag aaagccagca
     9841 tgggttactc ctgaaatgaa tacctgcgtg aggcatgcat tgtaaaaatc agcagcaaat
     9901 caggcctgag atagcgtcca ggcaaaacct ggaaaatttc ttagttttgc cggatatgaa
     9961 gtgaaaaggt gagatgcatc acgcttctcg cggtgtctgg gcgttcaaaa agggcagtaa
    10021 cagcagtgcg gaaatcccgg cggcgatggc gataaccaca aaaaatccgc tccagtgcca
    10081 ggtatcgagt actttcgcca gcggccaacc agcaagcgac gcaccaagat aagcaaacaa
    10141 gccgacaaac cccgtcgccg cccctgccgc ctctttgtgg gaacactctg ccgccgccat
    10201 gccgattaac atctgcgggc caaagacaaa aaaaccaatg gtgaagaagc aggttgcctg
    10261 catcacgtag ctggcaaatg gcatcagcca cagcgagccg actgaaagca aaattccggc
    10321 ggcgaaaatc aaattcatcg gcccgcggtt gccgttaaac agtttgtccg aaccccaacc
    10381 cgctaccagc gcaccgataa atccgcccag ttcaaacatt gtcactgccg tattcgccgt
    10441 gaccagatcg acgcccagcg tctcggacat atacaaattg ccccagtcgt tgatcgccgc
    10501 ccgaaccaca tagaccagca catagcaaaa cgaaagcagc cagatatacg gattcagcaa
    10561 cacatatttg gtgaggatct ctttacgcgt cagccctgcc ccttcttgtt gttgagcaat
    10621 ctccagtgcg tcgtgccgcc attcaccaac tgccggtaaa cctaacgcct gcgggcgatc
    10681 gcgcagccgc cagcagagaa aaatccccac gacgatcgcc atacaacccg caatcatcat
    10741 cccggcacgc cagccgtaat gcagcgcgct cgctgccatc acaatgggaa tgagtgcgcc
    10801 gccgacgtta tgcgccgtgt tccataatgc ccaccaaccg ccgcgctcgg tacgagaata
    10861 ccaggcggtt aacagacgcg cacacaccgg tgaaccccag ccctggaaaa aggcgttcaa
    10921 cacccagagc acggcaaacg cccatagcga cgtcgagaag ccaaacagaa tgttgataat
    10981 gcccgtggca ataagcccta tccccataaa ataacgggca tttgagcgat cgctgacaat
    11041 gccggagaca aacttcgaca caccgtaggt aatgtaaaac agggtcgcta acaggccaat
    11101 atcgctacgg ctgagcacgc cgttagcaag gatttctggt acggcggagt taaaactttt
    11161 acgcgtgaag taaaacagcg cgtaacccag ccagatggtc agcagaatat gccgacgcca
    11221 gtagcgatag cgggcatcaa tttcatgttt atcagtcatt aatggcgcat cggcaggcgc
    11281 tttcagaaac ggcaacatca tcgaacctta gacataacgt tgaggtagag aaacgctgac
    11341 acgcgtgccg tgcaggcagg agatggtcaa tgtgccaccc agcgccgtta cgcgctcgcg
    11401 cattccggta aggccaaaac cgtgttgccc ggaatctggc ggtaaaccgc tgccatcgtc
    11461 ttcaatcacc agcattaacc gctcatcatg ctgccagcct tgcagcgtga ccgcgctggc
    11521 atcggcatgt ttcacaatgt tgttcaaccc ttcctggcag acgcgaaata gcgtcacgcg
    11581 ctggttttcg cttaacgctg attcatcgat tcgccattcg agatgactga caatgccgcg
    11641 cccttccagc tccatttccc gcatcagtga gcggatggcc tgctccaggg tgagatcatc
    11701 cagctggcgc ggacgtaacc gccctaacaa gcggcgcacc gcgtcgtaaa cgcccaacga
    11761 caactgttcg atgagctgcc cgctctgttt cacgctggcg ttatccgccg cgagccgctg
    11821 gacaatgcca gcctgagtac gaatagcagt gatggtctga ccgatatcat cgtgcagctc
    11881 tcgcgccaca tcgcggcgca cgctctcttc ggtttccagc aaccgttcag cgagatgctg
    11941 attgcgcgcc agttcctttt gcagcgactg gttaagttca cgcaaccgct ggatgccagc
    12001 gcccagtaac aaccctgtca gactttgcac cagcagcgag agcaataaat ccaccggatg
    12061 atcgcgccag gtttgactgg cgatcagcgc gatggcgttc atcaatgtcg caatcagcgc
    12121 tccttgccaa ccatagtgcc aggccagcgc gataatcggc agcgccagac agaatggcgt
    12181 aaagcgcgac agttcgtctg gcaatcccaa ctggagccag agactgataa caaacagcag
    12241 caagtaccag accagatgtc gcccgcgcca gttgattggc tgagaaacca gtgacgggcc
    12301 gagcggcagc caggtgttat tggcgagata gtgccagaac accagacata tcggggccag
    12361 cgtcaggccg ccagttaaag tcagcagcag cgcattccac gactctttgc cgtgccaaag
    12421 ccagggcaac gactgcaaca acgccgccgc cgttaacgcc gcaccctgta acagcaaggt
    12481 gcgccagtca cgttgatggc gatagcgcga gatcagcgcc acgggcaata acgtcagtaa
    12541 actaccgatc atcaataagg agaaatgggt taaaccgacc gcctgcatta gccagtaaat
    12601 cagcagccac tccgcaccca gtagcaccgg ccagtatccg cgcgggcatt gcagcattag
    12661 ccctagccgc aggccaaacg gaaataacag caccgccata tcagggcgct caaccaggtg
    12721 caggctgata ctccacaggc aaaaccatgc ggcagagaag ataaaaaagc aggcaataac
    12781 ggtaattaaa cgggagaaca acgtcttcat caccagccat caaacatgcg gcgcgccagt
    12841 tcaacgtcgt tactgacgcc cagtttttcc atcagattgg cgcgatggac gtgtactgtt
    12901 ttcggcgaca agcccagttc ggcggcaatc tctttcaccg ccattccttg cgccagtttt
    12961 tctgccacct ggcgttcgcg tttggttagc gggtcctggc gaccagatgc cagtttaatg
    13021 gcaatatccg gcgtcagata acagccgcca gtggcaaccg tatgcaccgc agcaatgagt
    13081 tcatccgggc tacagcgttt ggagagaaag ccgcgcgccc ccgcgttaag cgcctgctca
    13141 accagcgccg gactgtcgtg aacggagagc ataattgtcg ccatgccttt cggcagctgg
    13201 cttagaagct ccagaccgga gatatcaggc atggagatat cgcaaataca cacctgcaca
    13261 ccgcgccccg gcagccccgc cagcgcctcg cgccccgaac caaactcggc aactacctgc
    13321 aaatcaggtt ccagccccag cagctgcgca aagccggagc ggacgataag gtgatcgtct
    13381 ataagggcaa cggtgatcat ggtcttgtcc tggcgggtaa taaaacgcgc ttaccttaac
    13441 gataagcgcg atgttgttca agccttgagc ggttactgcc aaaagctgcg ctcttgttgc
    13501 ttgtggaaag aagtgatgcc ttcaaggact tgtatatcga ctaaccatta aaaatgctgg
    13561 cggcattaat accttgttag tatccatttt gaataagtaa aatgta
//
LOCUS       DAPOXO010000114        13548 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.114, whole genome shotgun sequence.
ACCESSION   DAPOXO010000114 DAPOXO010000000
VERSION     DAPOXO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13548
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.114"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..688
                     /locus_tag="ROH59_004388"
     CDS             <1..688
                     /locus_tag="ROH59_004388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HDX4806792.1"
                     /translation="HIPVPRDGRDYDPDVLQKAVNDAVANIPQPADGKSLTPDDVRPM
                     LEQMVKEAVSHIHVPRDGRDYDPDVLQKAVLDAVSALPAPQDGRDATALEILPAIDDQ
                     KSFPRGTYATHQGGLWRAYEKTHGMRGWECLVDGVADIDVSMTGERLFSVVVRQSSGQ
                     RTEKTFSLPVMLYRGVFRAGETYHPGDTVTWGGSLWHCNSMTEDKPGEAHSSAWTLAA
                     KRGRDAGGGK"
     gene            685..1011
                     /locus_tag="ROH59_004389"
     CDS             685..1011
                     /locus_tag="ROH59_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDX4806793.1"
                     /translation="MTALLTLEEIKAHLRVDHDADDDMLMDKVRQATAVLLAYIQGSR
                     DKVIREDGELIPGEALTRMKGAAMRLTGMLYRNPDLAEREELLQGELPFSVSVLIYDL
                     RCPTVL"
     gene            1021..1371
                     /locus_tag="ROH59_004390"
     CDS             1021..1371
                     /locus_tag="ROH59_004390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDX4806794.1"
                     /translation="MAISAGRLTQMISVLNPVLTRNAAGEMTEEWVSCGKIHADIRGR
                     SSRERMQSGAEMAQAEIRIWVRGQSGREITAASRLHVLSGPWRDRILNVVGLPVPDAT
                     GGRLEILCRLGGEK"
     gene            1368..1814
                     /locus_tag="ROH59_004391"
     CDS             1368..1814
                     /locus_tag="ROH59_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDX4806795.1"
                     /translation="MIETLLDFSGLEDISRDLQLLSGAENNRVLREATRAGANVLKEE
                     VVSRAPVRRGKLRRNVVVLSRRSRDGGMESGVHIRGVNPDTGNSDNTMKADNPRNAFY
                     WRFVEMGTVNMPPHPFVRPAFDVRSEQAAQVAIARMNRAIDEVLRR"
     gene            1811..2155
                     /locus_tag="ROH59_004392"
     CDS             1811..2155
                     /locus_tag="ROH59_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3168 domain-containing protein"
                     /protein_id="HDX4806796.1"
                     /translation="MTEADLYPHLAHLAGGQVYPYVVPLLDGRPSVALPWVVFSLISS
                     VSADVMGGQAESSVSVQIDVYAGTVTQARQIRQDAREAIMLLAPGSVSEMQDYIPENR
                     CYRATLEFQVTV"
     gene            2222..2938
                     /locus_tag="ROH59_004393"
     CDS             2222..2938
                     /locus_tag="ROH59_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin domain-containing protein"
                     /protein_id="HDX4806797.1"
                     /translation="MSALYERSQLTQVMISSAPATAETMDKAEYLRLDCTIKEVQFTA
                     GQKQDIDVTTLCSTEQENINGLGASSEISMSGNFYLNQAQNALRDAYDNDALYAFKVL
                     FPSGKGFKFLAEVRQHTWSSGTNGVVAATFSLRMKGKPVSFVVPLAFVKNLDKTLTVN
                     TGALLTMSVSANGGTPPYKYAWKKDGQPVDGQTTDTFSKPGAQSADAGKYTCVVTDSA
                     EKAQSVTSVECTVTVSAAAG"
     gene            2953..3327
                     /locus_tag="ROH59_004394"
     CDS             2953..3327
                     /locus_tag="ROH59_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HDX4806798.1"
                     /translation="MKKDLKTLALARLSGFRHKTVKVPEWGNVSVVLREPSAEAWYLW
                     QEVLNGDGEDDDTLSVVAKTRRNLEADVTLFCDVLCDTDLQRVFAPDDREQVLAVYGP
                     VHARLLRQALELIADAESARKK"
     gene            3423..3632
                     /locus_tag="ROH59_004395"
     CDS             3423..3632
                     /locus_tag="ROH59_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4035 domain-containing protein"
                     /protein_id="HDX4806799.1"
                     /translation="MWMEFDRVSPLGDERGDIRNAQIVKAVFGAQGMNVALKDAMLCW
                     GEDEDKPEVDPFAALEDALSFAAQS"
     gene            3680..6922
                     /locus_tag="ROH59_004396"
     CDS             3680..6922
                     /locus_tag="ROH59_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDX4806800.1"
                     /translation="MATLRELIIKISANSQSFQSEIQRASRMGSEYYRTLQNGGRQAA
                     AVARVQRRALAELNSQLTEIRASAAGTAGAFAGAFATGHLISLADEWSSVNARLKQAS
                     QSSDEFSSSQKVLMDISQRTGTAFSDNAALFARSAASMREYGYSADDVLKVTEAISTG
                     LKISGASTAEAGSVITQFSQALAQGVLRGEEFNSVNESGDRIVRALAAGMGVARKDLK
                     AMADDGKLTADKVVPALISQLGVLRDEYAAMPETVSDGITKVENAFMAWVGGANEASG
                     ATKTLSGVLNGVAGNIDNVATAAGALVAVGVARYFGNMASGAVSATAGLVTAARNEVA
                     LAEAQLRGTQIATARARAAVYRAQQAVAAARGTEMQIAAEARLAATQERLNRNIAART
                     AAQNELNSTTAVGSRLMTGALGLVGGVPGLVMLGAAAWYTLYQNQEQARESARQYALT
                     IDEIAHKTPSMSLPEASDNEGRTRAALAEQNRLIDEQASRVKSLQEKIAGYQYVLANP
                     GWTTGDGFMINHLTSVKTVTEGLSQATEQLAVEQSRLAQMQEKAQSIQDVLAGLEDRR
                     VALIRQQAAEQNKVYQSMLVMNGQHTEFNRLLGLGNELLQQRQGLVNVPLRLPQATLD
                     DKQQSALTKTERELALSRLKGEEKERARLGYAADDLGFVGDSYQEARQRYISNALEAW
                     RNNEANKPKSRGGKSETEKAEDSFSRLLKQQKEQLALAGQNTELAKLKYQTAQGELKT
                     LTEMQKQELLRNAALIDQQKIREQLRSREETLKNDNVAARASNEAELLGYGQGERARE
                     RMRELQQIRDSFRQKDADLQSQYQTGDISEDFYRQARAQNAQYLSERLKDQAAFYAES
                     DAQRADWQKGLQEGLSNWVDNASDYASQAAQLATEGISGMVNNITEMLNGNKVEWRNW
                     ASSVLQEISKVLMNAAIVNGIKTAANGMSGAGGFIGSIGDWLGGAVANAKGGVYTSAN
                     LSAYSNSIVDTPTYFAFAKGAGLMGEAGPEAIMPLTRAADGSLGVRAVGSMNGSAGLV
                     YSPVYHIAIQNDGANGQIGAEAAGSLVQLIDQRVQAVMLSMRRDGGMLSG"
     gene            6915..7256
                     /locus_tag="ROH59_004397"
     CDS             6915..7256
                     /locus_tag="ROH59_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4806801.1"
                     /translation="MAEIKTLHLVPREGMQVSEKPSVVRVRFGDGYEQRRPTGLNARL
                     KTFQAVFRVTDEPTRRWLDEFLSWHGGYRAFLWRPPKHNLTVRVVCREWSVTDNARHS
                     DFSCTIEQVVN"
     gene            7256..7954
                     /locus_tag="ROH59_004398"
     CDS             7256..7954
                     /locus_tag="ROH59_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDX4806802.1"
                     /translation="MQDIREESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNE
                     KGEPVTWQGRQYQAYPIDGSGFEMSGKGSSARPSLTVSNLFGLVTGMAEDLQSLVGAT
                     VVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSQLTAMTASFVLATPTETDG
                     ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCELRRNV
                     GNFGGFLSINKLSQ"
     gene            7965..8708
                     /locus_tag="ROH59_004399"
     CDS             7965..8708
                     /locus_tag="ROH59_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4806803.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVISTSEGEWYIPCVNISAEPE
                     AYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGDIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGTEMPDFHREDDWWRNGQNLYLDNMAVT
                     GFYRVPLSSAQAGDILLCCFGASVPNHAAIYCGNGELLHHLPEQLSKRERYSEKWQRR
                     THSVWRHRHWHASAFTGIYNDLAAASACM"
     gene            8654..9286
                     /locus_tag="ROH59_004400"
     CDS             8654..9286
                     /locus_tag="ROH59_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDX4806804.1"
                     /translation="MCLHGDLQRFGRRLSLYVNTAAEAIRALSLQVPGFRRQMNEGWY
                     QIRIAGYDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVGSFFTA
                     GASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTY
                     FSSLDNMIAQGNPMPVPYGEMLVGSRRISQDISTRDEGGGGTVVVIGRQG"
     gene            9629..13102
                     /locus_tag="ROH59_004401"
     CDS             9629..13102
                     /locus_tag="ROH59_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDX4806805.1"
                     /translation="MGKGGGKAHTPREAKDNLKSTQMMSVIDAIGEGPIEGPVKGLQS
                     ILVNKTPLTDTDGNPVIHGVTAVWRAGEQEQTPPEGFESSGAETGLGVEVTKAKPVTR
                     TITSANIDRLRVTFGVQSLVETTSKGDRNPASVRLLIQLQRNGNWVTEKDVTINGKTT
                     SQFLASVILDNLPPRPFNIRMVRETADSTTDQLQNKTLWSSYTEIIDVKQCYPNTAIV
                     GLQVDAEQFGGQQMTVNYHIRGRIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYAIGQYCDQTVPDGFGGTEPRMTFNAYLAQQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDVVWPYTNSDVVVDDNGVGFRYSFSAL
                     KDRHTAVEVNYTDPQNGWQTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLW
                     VIKTELLETQTVDFTLGSQGLRHTPGDIIEICDNDYAGTLTGGRVLSIDAATRTLTLD
                     REVTLPETGTSAVNLINGSGKPVSVDITAHPAPDRIQVSTLPDGVETYGVWGLSLPSL
                     RRRLFRCVSIRENTDGTFAITAVQHVPEKEAIVDNGARFEPQSGSLNSVIPPAVQHLT
                     VEVSAADGQYLAQAKWDTPRVVKGVRFSLRLTSGKGTDARLVTTAITADTEHRFSGLP
                     LGEYTLTVRAINSYGQQGEPATTTFRIAAPAAPSRIELTPGYFQITATPHLAVYDPTV
                     QFEFWFSEKRIADIRQVETAARYLGSALYWIAASINIKPGHDYYFYIRSVNTVGKSAF
                     VEAVGRASDDAEGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITNVSNEI
                     TQTVNKKLENQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIENTP
                     AGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITSGGNPPA
                     FSLTPDGRLTAKNADISGNVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVGKA
                     FPRDSRAPERWPSGTITVRVYDDQPFDRQIVIPAVAFSGAKHEKEHTDIYSSCRLIVR
                     KNGAEIYNRTALDNTLIYSGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLVVV
                     MKKATAGITIS"
     gene            13170..>13548
                     /locus_tag="ROH59_004402"
     CDS             13170..>13548
                     /locus_tag="ROH59_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HDX4806806.1"
                     /translation="MRKLCAVILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPG
                     SDDLNGINVKYRYEFTDALGLITSFSYANAEDEQKTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVST"
BASE COUNT         3063 a         3316 c         4400 g         2769 t
ORIGIN      
        1 ccatatccct gttccgcgcg acggtcgtga ctatgatccc gatgttctgc agaaggcggt
       61 gaatgatgcg gtcgcaaata ttccgcagcc ggcagacggt aaaagtctca ccccggatga
      121 tgtgcgtccg atgcttgaac agatggtgaa ggaggcggta agccatattc atgttccgcg
      181 tgatggtcgt gactacgatc cggatgttct gcagaaggcg gttctggatg cggtgagtgc
      241 cctgccggct ccgcaggacg ggcgtgatgc cacggctctg gaaatactcc ccgccattga
      301 cgatcaaaaa tcctttcccc ggggcacgta tgccacacac cagggcggac tctggcgggc
      361 gtatgaaaaa acgcacggga tgcggggatg ggaatgcctg gttgacgggg tggcggatat
      421 tgacgtcagc atgacgggtg agcggttgtt ctctgtggtg gtccggcaga gcagtggcca
      481 gcgtacggaa aaaacatttt ccctgccggt gatgctctac cgcggtgtgt tcagagccgg
      541 tgaaacctac caccccggcg atacggtgac gtgggggggc tcgctgtggc actgcaacag
      601 tatgaccgaa gataaacccg gagaagctca ttcatcagcc tggaccctgg ctgcaaaacg
      661 tgggcgggat gcaggaggcg gaaaatgacg gcattactga cactggaaga gatcaaggca
      721 catctgcgtg tcgaccatga cgcggatgat gacatgctga tggacaaggt tcgtcaggct
      781 accgccgtgc tgctggccta cattcagggc agccgggata aagtgatccg tgaggacggt
      841 gaactgatcc cgggcgaggc attaacccgg atgaaggggg ctgccatgcg actgaccggg
      901 atgctgtacc ggaatccgga tcttgcggag cgggaagaac tgcttcaggg ggagctgccg
      961 ttttctgttt ccgtgctgat ttacgatttg cgttgtccga cggtgttatg aggaggggga
     1021 atggcaatat ctgcaggtcg tctgacacag atgataagtg ttctgaaccc ggtgttaacc
     1081 cgtaacgctg ccggagaaat gacggaagaa tgggtgtcat gcgggaaaat tcatgcggat
     1141 atccgaggca ggagcagccg ggagcggatg cagtccggtg cggaaatggc gcaggcggaa
     1201 atccgcatct gggtgcgcgg tcagtccggt cgggaaatca cggcagcgtc acgacttcat
     1261 gtgctgagtg gtccatggcg tgaccggatc ctgaacgttg tcgggctgcc cgtgccggat
     1321 gcgaccggcg ggcgtctgga aattctctgt cggctgggag gggaaaaatg atcgaaaccc
     1381 tgctggattt ttcggggctg gaggacatca gccgcgattt gcagcttctg agtggtgcgg
     1441 aaaataaccg ggtgctgcgt gaggcaaccc gtgcgggtgc gaatgtgctg aaagaagaag
     1501 tggtgtcacg ggcaccggta cgcaggggaa aactgcgccg caatgtggtg gtcctttccc
     1561 ggcgctcccg cgatggcggg atggaatccg gtgtccatat ccgtggtgtt aatccggaca
     1621 ccggtaacag cgataacacc atgaaggcgg ataacccgcg caatgctttc tactggcggt
     1681 ttgtggaaat ggggaccgtg aatatgccac cgcacccgtt tgtgcgcccg gcgtttgatg
     1741 tgcgcagtga acaggcagct caggtggcga ttgcgcggat gaaccgggcc attgatgagg
     1801 tactgagacg atgacggagg cggatttgta tcctcatctg gcgcatcttg ccggcgggca
     1861 ggtgtacccg tatgtggtcc ccctgctgga tggcaggccg tcggtggcgc ttccgtgggt
     1921 ggttttcagc ctgatttcat cggtgtctgc ggacgtgatg ggcgggcagg cggagtcctc
     1981 agtgtcggtg cagatagacg tttatgccgg gactgtgacg caggcgcgtc agatacgtca
     2041 ggacgcccgt gaagccataa tgctgctggc cccgggatcc gtcagtgaaa tgcaggacta
     2101 tattccggaa aaccgctgtt accgtgcaac cctggagttt caggtcacgg tgtgactttt
     2161 tctttttttc tacaaaaccc ataccccgcc gcgtgcgggt tttttattat caggaggcag
     2221 aatgtctgct ttgtatgaac gctcacagct gacgcaggtg atgatttcat ctgccccggc
     2281 gactgctgaa actatggata aggcggaata tctgcgcctg gactgcacca tcaaggaagt
     2341 ccagttcacc gctggtcaga aacaggatat tgatgtgacc acgctctgct ccaccgagca
     2401 ggagaacatc aacggtctgg gggcgtcgtc tgagatttcc atgtcgggta atttttatct
     2461 gaatcaggcc cagaacgccc tgcgtgatgc ctatgacaat gacgcgttgt atgcgtttaa
     2521 ggtgctgttt ccgtccggta agggctttaa gttcctggcg gaagtgcgtc agcacacctg
     2581 gtcatccggt accaacggcg tggtggcagc aacgttttca ctgcgtatga aaggcaaacc
     2641 ggtgtccttt gtggtaccgc tggcgtttgt gaaaaatctg gataaaacac ttaccgtgaa
     2701 tacaggtgcg ctgctgacaa tgtcagtcag tgccaacggg ggaacgccgc cgtataaata
     2761 cgcctggaag aaggatggtc agccggttga cgggcagacg acagacacct tcagtaagcc
     2821 aggtgcgcag tccgctgatg cggggaaata tacctgcgtg gtgaccgatt cggcagagaa
     2881 agcacagagt gtgacgtctg ttgaatgcac cgtgacagtg agcgcagccg ccggataagg
     2941 ggatgggtca tcatgaaaaa ggatctgaaa acgctggcgc tggccagact gtcagggttt
     3001 cgtcataaaa cggtgaaggt gccggaatgg ggtaatgtca gcgtggtgct gcgggagcct
     3061 tcggcagagg cctggtatct gtggcaggaa gtgctcaatg gtgatggaga ggatgacgat
     3121 accctgtcgg tggtggcgaa aacccgccgt aacctagaag cggatgtgac gctgttctgc
     3181 gatgtcctgt gtgatacgga tctgcagcgg gtgttcgctc cggacgaccg tgagcaggtg
     3241 ctggccgtct atggtccggt acatgcccgg ttgctgcgtc aggcactgga actgatcgct
     3301 gatgcagagt cggccagaaa aaagtagccc gcccggaaat tcgctttctg atgcgacttg
     3361 cgctccgtct ggggcgcacc ttatccgaac tgcggcacag cctgagtgtg agcgaggcga
     3421 tgatgtggat ggagttcgac agggtatccc cgctgggtga tgagcgcggg gatatccgta
     3481 atgcacagat cgtgaaagcg gtttttgggg cacaggggat gaatgttgca ctgaaggacg
     3541 ccatgctctg ctggggcgag gatgaggata agccggaggt ggatccgttt gcggcgctgg
     3601 aagacgcgct gagcttcgca gcacagtcat gaatgatgag aaccgctgag gcggtttttt
     3661 tacgcccgga gaaaggtgaa tggcgacgtt acgtgaactg attatcaaaa tttcggcaaa
     3721 ttcgcagtca ttccagtcgg agatccagcg ggcttcccgc atgggcagtg aatattaccg
     3781 gaccctgcag aatggcgggc gtcaggctgc cgcagtcgcc cgggtgcagc gacgcgccct
     3841 ggctgagctg aacagccagt tgacggaaat ccgcgcttca gctgccggaa cggcgggggc
     3901 atttgcaggt gcctttgcca ccggacacct gatttctctg gccgatgaat ggagttccgt
     3961 gaatgcccga ctgaaacagg cgtcgcagtc atccgatgaa ttttcgtcat cacagaaagt
     4021 gctgatggat atcagccagc ggacgggcac ggcattttca gataatgcgg ccctgtttgc
     4081 ccgctcggca gcctcaatgc gtgaatatgg ttacagtgct gatgatgtgc tgaaggtgac
     4141 ggaggccatt tccacggggc tgaaaatctc cggtgccagt acggcagagg cgggctcggt
     4201 gatcacccag ttcagccagg cgctggcaca gggtgtgtta cgcggtgagg aatttaattc
     4261 ggtcaatgaa agcggagacc ggatcgtacg tgcactggct gcgggtatgg gcgtggcccg
     4321 taaagacctt aaggcgatgg cggacgacgg caaactgacg gcggataaag tcgttcctgc
     4381 gttaatcagc cagctggggg tattgcgtga tgaatatgcc gccatgccgg aaacggtctc
     4441 tgacgggatc acaaaggtgg aaaacgcctt tatggcctgg gtgggtggcg cgaatgaagc
     4501 cagcggagcg acgaaaacgc tctccggcgt gctgaacggt gttgccggta atattgataa
     4561 tgtggcaaca gccgcggggg cgctggttgc cgtcggggtt gcccggtact ttggcaatat
     4621 ggcctccgga gcggtgtctg ccacggcagg acttgtgacg gcagcacgta atgaagtggc
     4681 actggcggaa gcacagctca gggggacgca gattgccacg gcgcgggcaa gggcagccgt
     4741 gtaccgtgca cagcaggctg tggcggcagc ccgcgggacg gagatgcaga ttgctgcaga
     4801 agcccgtctg gcggccacac aggaacgcct gaacagaaat attgctgcca gaaccgcagc
     4861 ccagaatgag ctgaacagta caacggcggt gggctcacgt ctgatgactg gtgcgttggg
     4921 actggttggt ggcgtacccg gactggtgat gctgggggca gcagcatggt atacgctgta
     4981 ccagaatcag gagcaggcca gggagtcagc gcgccagtat gcactgacga tagatgaaat
     5041 cgcgcataaa acgccgtcaa tgtctttgcc tgaagcctca gataatgaag gacgaacacg
     5101 ggcggcgctg gcagagcaga accggctgat tgatgaacag gccagccggg tgaaatccct
     5161 gcaggaaaaa atcgctggat atcagtatgt tctggctaac cctggctgga caaccggtga
     5221 cggattcatg ataaaccatc tgacatcggt gaagaccgtg acggaagggc tttctcaggc
     5281 aacagagcag cttgccgttg agcagtcccg tctggcacag atgcaggaaa aagcgcagtc
     5341 cattcaggat gtgcttgccg ggctggaaga ccgtcgtgtg gcgttaattc gtcagcaggc
     5401 ggcagagcag aataaggtgt accagtccat gctggttatg aacggtcagc atacggaatt
     5461 caaccgtctg ctggggctgg ggaatgaact gcttcagcag cgtcagggac tggtgaatgt
     5521 accgttacgg ctgccgcagg ccaccctgga tgataaacag cagagcgccc tgacaaaaac
     5581 agaacgtgag ctggccctgt cccgactgaa gggggaggaa aaagagcgtg cccggctggg
     5641 gtatgcggcg gatgaccttg gttttgtggg ggattcgtat caggaggcga gacagcgtta
     5701 tatcagtaat gctctggaag cctggcgtaa taacgaggcg aacaaaccta aatcccgggg
     5761 tggaaaatca gagacggaaa aagcggaaga cagtttttcc cggctactga agcagcagaa
     5821 agagcaactg gcactggcgg gtcagaatac agagctggcg aagctgaagt accagactgc
     5881 gcagggcgaa ctgaaaaccc tgacggagat gcagaagcag gaactgctgc gtaacgcggc
     5941 cctgattgac cagcaaaaaa tccgggaaca gttgcgatcc cgggaagaga ccctgaagaa
     6001 tgataatgtg gctgcgcgtg catcaaatga agccgaactg ctgggatacg ggcagggaga
     6061 acgagccagg gaacgcatgc gggagttgca gcagatccgt gacagcttcc gccagaagga
     6121 tgcggacctt cagtctcagt atcagaccgg ggatatcagt gaggattttt acagacaggc
     6181 acgggcacag aacgcgcagt atctgagcga acgccttaag gaccaggcag ccttttatgc
     6241 cgaatcggat gcgcagcgtg cggactggca gaaaggcttg caggaggggc tcagtaactg
     6301 ggtggacaat gcatccgatt acgcctcaca ggcagcacag cttgcgacgg agggtatctc
     6361 agggatggtg aataacatca cggagatgct gaacggaaac aaagtggaat ggcgcaactg
     6421 ggcctcatcc gtactgcagg aaatctcaaa agttcttatg aatgctgcga ttgtcaacgg
     6481 aattaagacg gcggcaaacg gtatgtccgg tgcgggagga tttattggca gcattggtga
     6541 ctggctgggc ggtgcggtgg ccaatgcaaa aggcggcgtg tatacctcgg caaacctgag
     6601 tgcgtacagc aacagcattg tggacacgcc cacgtacttt gcgtttgcaa aaggggccgg
     6661 gctgatgggg gaagccggac ctgaagccat tatgcccctg acccgggcgg cggatggctc
     6721 gctgggcgta cgcgcggtgg gcagtatgaa cggcagtgcc ggtctggtgt attccccggt
     6781 ctaccacatc gccattcaga atgacggggc taacggacag ataggggcgg aggcggcagg
     6841 cagtcttgtg cagctgattg accagcgggt gcaggcggtg atgctgtcca tgcgacgtga
     6901 cggaggaatg ctgagtggct gagataaaaa cgctgcatct ggtcccgcgt gaagggatgc
     6961 aggtgagtga gaaaccgtcg gtggtgaggg ttcggtttgg tgacggttat gaacagcgcc
     7021 gaccgacggg acttaatgcc agactgaaga cgtttcaggc ggtgttccgg gtgacggatg
     7081 aaccaacccg gcgctggctg gatgaatttt tatcgtggca tggtggttac cgtgcctttt
     7141 tgtggcgacc gccgaaacat aacctgacgg tgagggtggt gtgccgggag tggagcgtca
     7201 cagataacgc caggcacagt gatttcagtt gtacgattga gcaggtggtg aactgatgca
     7261 ggatattcgc gaagaaagtc tgaacgagtc ggttaagtca gagcagtcac cgcgggtggt
     7321 actctgggaa atcgacctga cggtacaggg cggtgagcgg tattttttct gtaatgagct
     7381 gaatgaaaaa ggggagccgg tcacctggca ggggcggcaa tatcaggcat acccgattga
     7441 cggcagcggt tttgagatga gcgggaaggg cagcagtgcc agaccgtcgc tgacggtgtc
     7501 caatctgttc ggtctggtca ccgggatggc ggaagacctg cagagtctgg tgggggccac
     7561 ggtggtccgc cgccgggtgt atgcccgttt tctggatgcg gtgaatttcg ttgcgggcaa
     7621 tccggaggcg gacccggagc aggagctgag tgaccgctgg gtggtggagc agatgtcgca
     7681 gctgacagcc atgacggcct cgtttgtgct ggctacaccg accgagacgg atggggcgct
     7741 gtttcccggt cgcatcatgc tggcgaacac ctgtatgtgg gattaccggg gagatgaatg
     7801 cgggtataac ggtcctgcgg tggcggatga gttcgacaac cccaccacgg atatccgtaa
     7861 ggacagatgc agcaagtgca tgcgcgggtg tgaactgcgc aggaatgtcg gcaattttgg
     7921 cggtttcctt tccattaata aactttcgca gtaaatcccg gtttatgaca cagactgaat
     7981 cagcgattct ggcgcatgcc cggcggtgtg cgcctgcgga gtcgtgcggc ttcgtgataa
     8041 gcacgtcgga gggggagtgg tatatccctt gtgtgaatat ttctgcagag ccggaggcgt
     8101 attttcgtat cgcaccggaa gactggctgc gggcagagat gcagggggag attgtggcac
     8161 tggtccacag tcatcccggt gggctgccct ggctgagcga ggctgaccgg cggctgcaga
     8221 taaaaagcgc actgccctgg tggctggtct gccggggtga cattcacaaa ttccgctgtg
     8281 tgccacatct gacaggacgg cgctttgagc acggggtgac ggactgttac acgctgttcc
     8341 gggatgctta tcatctggcg gggactgaaa tgccggattt tcatcgcgag gatgactggt
     8401 ggcgcaacgg tcagaacctt tacctggaca atatggcggt caccggcttt taccgggtgc
     8461 ccctgtcctc tgcacaggcg ggcgatattc tgctgtgctg ctttggtgct tcggtaccga
     8521 accatgccgc catttactgc ggcaacggtg agctgcttca ccatctgcct gaacaactga
     8581 gtaaacggga gaggtattcc gaaaaatggc aacgacgaac gcattctgtc tggcgtcacc
     8641 gccactggca cgcatctgcc ttcacgggga tttacaacga tttggccgcc gcctcagcct
     8701 gtatgtgaac acggcagcgg aagccatccg ggcgctgtcg ttacaggtgc cgggctttcg
     8761 ccgtcagatg aacgaaggct ggtaccagat acgtattgcc ggttatgaca cggcaccgga
     8821 ggcggtgtac gcccgtcttc acgaacagct gggtgaggga acggtcatcc atattgtgcc
     8881 gcgactggcc ggggccggaa agggtggact gcagattgtg ctgggggcgg cagccatcgt
     8941 gggctctttc ttcactgccg gggcatcaat ggcgttatgg ggttcagccc tggcagccgg
     9001 tggtttttct gccaccacga tgctgttttc acttggagcc agcatgattc tgggcggtgt
     9061 ggcccagatg ctggccccga aggcaaaaac accggattac cgcgcaacgg ataacggcag
     9121 acagaacacg tacttttcct cgctggataa catgattgcc caggggaacc cgatgccggt
     9181 gccttacggg gaaatgctgg ttggctcccg ccgtatatcc caggacatca gcacccgtga
     9241 tgaaggcggg ggcggaacgg tcgtggttat cgggcgacag ggataaaaca taaaaaaatc
     9301 ccgcagtgat cgcggagctg cggggacaga caaatgaaga tcaatgttaa ggagttgttt
     9361 ttgttactcg ggcaaaaaaa cactaacgca gcgaaattat aagcgccaca gtcagtgtgt
     9421 gaaaatgtga agatattcag aatttttatg ccattaccgg ttttaaccaa caggattatc
     9481 ggtgggcatg aaagaaaacc ccggtatctg ctgataccgg ggtttctctt tagcatggca
     9541 gaaatgtgtt tcatgctttt cgggcgaagg atatccgact tctgtacgga atggcaagtg
     9601 gcggttaatt tattcagggg aaggctgtat gggaaaaggt ggcggtaagg cacacacgcc
     9661 tcgtgaggcg aaggataatc tcaaatccac gcagatgatg agcgtgattg atgcgattgg
     9721 tgagggaccg atagaaggtc cggtgaaggg actgcagagt attctggtga acaaaacccc
     9781 actgacggac acggacggca atcccgtgat acacggtgtg acggcggtct ggcgcgccgg
     9841 ggagcaggag cagacaccac cggaaggctt tgagtcctcc ggagctgaaa ccggactggg
     9901 cgtggaagtg acgaaggcaa aaccggtgac gcgcaccatt acgtccgcga acattgaccg
     9961 cctgcgggtt accttcgggg tgcagtcact ggtggagacc acctcaaagg gtgaccgtaa
    10021 cccggcatcc gtccgcctgc tgattcagtt acagcgtaac ggtaactggg tgacagaaaa
    10081 ggacgtcacc attaacggca agaccacctc acagttcctg gcctcggtga ttctggataa
    10141 tctgcctccc cggcccttta acatccggat ggtcagggag acggcggaca gcaccacgga
    10201 ccagctgcag aataagacgc tgtggtcgtc atacaccgaa atcatcgatg tgaaacagtg
    10261 ctacccgaac acggccattg tggggctgca ggtggatgcg gagcagttcg gcggccagca
    10321 gatgacggtg aactaccata tccgcggtcg catcatccag gtgccgtcaa actatgaccc
    10381 ggaaaaacgc acgtatagtg gtatctggga cggcagtctg aaaccggcat acagcaacaa
    10441 cccggcctgg tgtctgtggg acatgctgac tcacccgcgc tacggcatgg gaaaacgtct
    10501 gggggcggcg gatgtggaca agtgggcgct gtatgccatc gggcagtact gcgaccagac
    10561 ggtcccggat ggtttcgggg ggaccgagcc gcggatgacc tttaatgcgt acctggcaca
    10621 acagcgtaag gcgtgggacg ttctcagtga tttctgctct gcgatgcgct gtatgccggt
    10681 atggaacggt cagacgctga cgttcgttca ggaccgcccg tcggatgtgg tgtggccgta
    10741 caccaacagc gatgtggtgg tggatgataa cggcgtggga ttccgctaca gcttcagtgc
    10801 cctgaaggac cggcacacgg cggtggaggt gaattacacc gacccgcaga acggctggca
    10861 gacctccacg gaactggtgg aagacccgga agccatactg cgctacggac gcaacctgct
    10921 gaagatggac gcgttcggct gtaccagccg cggtcaggcc caccgtgccg gactgtgggt
    10981 gataaagacc gaactgctgg aaacgcagac ggtggatttc acgctcgggt ctcaggggct
    11041 gcggcacaca cccggtgaca ttattgaaat ctgtgataat gactatgccg ggaccctgac
    11101 cggcggacgt gtcctgtcca ttgatgctgc cacccgcacc ctgacgctgg accgtgaggt
    11161 taccctgccg gagacaggta catcggcggt gaacctgatt aacggcagcg gtaagccggt
    11221 gagtgtggac atcaccgcac accccgcgcc ggaccggata caggtcagta ccctgcctga
    11281 tggtgtggag acatacgggg tgtggggact ctccctgccg tcactgcgcc gtcgcctgtt
    11341 ccgctgtgtc tccatccggg aaaacacgga cggcaccttt gccatcacgg cggtgcagca
    11401 cgtaccggaa aaagaagcca tcgtggataa cggtgcccgc tttgagccgc agtcaggttc
    11461 cctgaacagc gtcatcccac cggcagtgca gcacctgacg gtggaggtga gcgcagctga
    11521 cggccagtat ctggcgcagg cgaaatggga cacgccgcgg gtggtgaagg gtgtgcgctt
    11581 cagtctgcgc ctgaccagtg gtaagggaac ggatgccaga ctggtgacca ccgccatcac
    11641 cgcagacacg gagcaccgtt tcagcggcct gccgctcggg gaatacaccc tgacggtgcg
    11701 ggcgataaac agctatggcc agcagggtga acctgccacc accaccttcc ggattgccgc
    11761 accggcagca ccgtcgcgga ttgagctgac gccgggctat tttcagataa ccgcaacgcc
    11821 acatcttgcc gtttatgacc cgacggtaca gtttgagttc tggttctcgg aaaagcggat
    11881 tgcggatatc aggcaggttg aaaccgcagc ccgctatctt ggctcggcgc tgtactggat
    11941 agctgccagt atcaatatca aaccgggcca tgattattat ttttatatcc gcagtgtgaa
    12001 tactgttggc aaatcggcat tcgtggaggc tgtcggtcgg gcgagcgatg atgcggaagg
    12061 ttacctggat tttttcaaag gagaaatcgg gaaaacacat ctggcccagg agctgtggac
    12121 gcagattgat aacggtcagc ttgcgccgga cctggctgaa atcaggacgt ccattacgaa
    12181 tgtcagcaat gaaatcacgc agaccgtcaa taaaaaactg gaaaatcaga gtgcggcaat
    12241 ccagcagata cagaaagttc aggttgatac aaataataac ctgaacagca tgtgggccgt
    12301 gaaactgcag cagatgcagg acggacgcct ttatattgcg ggtatcggtg ccggtattga
    12361 gaatacgcca gcaggaatgc agagtcaggt gctgctggcg gcagacagga ttgcgatgat
    12421 taatcctgcg aatggcaaca caaagccgat gtttgttggt cagggcgatc agatatttat
    12481 gaatgaagtg ttcctgaaat atctgacggc tcccaccatt accagcggcg gtaatcctcc
    12541 ggcattttcc ctgacaccgg acgggcggct gacggcgaaa aatgccgata tcagcggtaa
    12601 cgtgaatgcg aactccggga cgctcaacaa cgtcacgatt aacgagaact gtcgggttct
    12661 gggaaaattg tccgcgaacc agattgaagg cgatctcgtt aaaacagtgg gcaaagcttt
    12721 cccccgggac tcccgtgcac cggagcggtg gccatcagga accattaccg tcagggttta
    12781 tgacgatcag ccgtttgacc ggcagattgt tattccggcg gtggcattca gcggcgctaa
    12841 acatgagaaa gagcatactg atatttactc ctcatgccgt ctgatagtgc ggaaaaacgg
    12901 tgctgaaatt tataaccgta ccgcgctgga taatacgctg atttacagtg gtgttattga
    12961 tatgcctgcc ggtcacggtc acatgacact ggagttttcg gtgtcagcat ggctggtaaa
    13021 taactggtat cccacagcaa gtatcagcga tttgctggtt gtggtgatga agaaagccac
    13081 tgcaggcatc acgattagct gaattttata acccagatac gggcgccaga aatggcgcct
    13141 tttttattgc agaaaagcga gaggtaatta tgcgtaaatt atgtgctgtt attttgtccg
    13201 cagtagtctg gcaggtcgcc gctgctacgc cagcgagtgc agcagaacat cagtccacgc
    13261 tgagcgcggg gtatctccat gcctcgacga acgttcccgg tagtgatgat ctgaacggga
    13321 ttaacgtgaa ataccgttat gagtttacgg acgcgctggg gctgattacg tccttcagtt
    13381 atgccaatgc tgaggatgag caaaaaacgc gctacagcga tacccgctgg catgaagatt
    13441 ccgtgcgtaa ccgctggttc agcgtgatgg cggggccgtc tgtacgcgtg aatgaatggt
    13501 tcagcgcgta tgcgatggcg ggtgtggctt acagccgtgt gtcgactt
//
LOCUS       DAPOXO010000115        13489 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPOXO010000115 DAPOXO010000000
VERSION     DAPOXO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13489
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.115"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            100..633
                     /gene="ymdB"
                     /locus_tag="ROH59_004403"
     CDS             100..633
                     /gene="ymdB"
                     /locus_tag="ROH59_004403"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HDX4806807.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAHLYERLLTQQGDE"
     gene            575..2056
                     /gene="clsC"
                     /locus_tag="ROH59_004404"
     CDS             575..2056
                     /gene="clsC"
                     /locus_tag="ROH59_004404"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsC"
                     /protein_id="HDX4806808.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADHIELPASWHNDVMTHRYLRKMESSPFIHHLVDGTLPLIWAKTCLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVKLASILPVEWLL"
     gene            complement(2064..3221)
                     /gene="mdoC"
                     /locus_tag="ROH59_004405"
     CDS             complement(2064..3221)
                     /gene="mdoC"
                     /locus_tag="ROH59_004405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706958.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HDX4806809.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEP
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNLRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            3615..5150
                     /gene="mdoG"
                     /locus_tag="ROH59_004406"
     CDS             3615..5150
                     /gene="mdoG"
                     /locus_tag="ROH59_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HDX4806810.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            5143..7686
                     /gene="mdoH"
                     /locus_tag="ROH59_004407"
     CDS             5143..7686
                     /gene="mdoH"
                     /locus_tag="ROH59_004407"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HDX4806811.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDVWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHL
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            7858..8085
                     /locus_tag="ROH59_004408"
     CDS             7858..8085
                     /locus_tag="ROH59_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDX4806812.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDIHHGPYE"
     gene            complement(8086..8460)
                     /locus_tag="ROH59_004409"
     CDS             complement(8086..8460)
                     /locus_tag="ROH59_004409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secY/secA suppressor protein"
                     /protein_id="HDX4806813.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAENANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQDENTLHEWDEGE
                     FQLEPPLDTEEGRTAADEWDER"
     gene            complement(8543..9769)
                     /gene="mdtG"
                     /locus_tag="ROH59_004410"
     CDS             complement(8543..9769)
                     /gene="mdtG"
                     /locus_tag="ROH59_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HDX4806814.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQISN"
     gene            complement(9941..10861)
                     /gene="lpxL"
                     /locus_tag="ROH59_004411"
     CDS             complement(9941..10861)
                     /gene="lpxL"
                     /locus_tag="ROH59_004411"
                     /EC_number="2.3.1.241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) lauroyltransferase"
                     /protein_id="HDX4806815.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLARMSGACLVPFVPRRKPDGKGYQLIILPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            11086..12138
                     /locus_tag="ROH59_004412"
     CDS             11086..12138
                     /locus_tag="ROH59_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706977.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDX4806816.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKVTRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLGIPDPTE"
     gene            complement(12180..12755)
                     /locus_tag="ROH59_004413"
     CDS             complement(12180..12755)
                     /locus_tag="ROH59_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HDX4806817.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGNLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(12759..13325)
                     /locus_tag="ROH59_004414"
     CDS             complement(12759..13325)
                     /locus_tag="ROH59_004414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HDX4806818.1"
                     /translation="MSFTNTPERYGVISAALHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLPSYSPMTRLAAKAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLSDAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
BASE COUNT         3411 a         3240 c         3499 g         3339 t
ORIGIN      
        1 actaagtttc tgaacaactc acgttgctaa gcagaaaaat gcgatttaac taaaaagcct
       61 gctgtacact taggaaacaa gaaggtgtaa ggaggcgtta tgaaaacgcg tattcatgtt
      121 gtgcagggtg atattaccaa actggccgtt gatgtgattg tgaatgcggc taatccgtca
      181 ttaatgggag gcggcggcgt cgatggggcc attcatcgcg cagcgggtcc ggccctgctg
      241 gatgcctgtt taaaagtcag gcagcagcag ggcgattgcc ctacggggca tgccgttatt
      301 acgcttgcag gcgatcttcc cgctaaagcc gtagtgcaca ccgtcgggcc agtctggcgt
      361 ggtggtgaac aaaacgaaga ccagcttttg caggatgcct atctcaatag cctacgactg
      421 gtggcggcaa acagctatac gtcagtggct tttcctgcaa tcagtactgg ggtttatggt
      481 tatccccgtg cggcagcggc tgaaatcgca gtaaaaaccg tttcagaatt tattacccgt
      541 cacgctttac ccgaacaggt atactttgtc tgttatgatg aagaaaacgc ccacctctac
      601 gaaagactcc ttacccaaca aggagatgaa tgatttgcct cggctggcga gcgcggtgct
      661 gccactgtgt tcgcaacatc ccggtcagtg tggacttttt cctctggaga aaagtctgga
      721 tgcgtttgcc gcccggtatc gtctggctga aatggcagag catacgctgg atgttcagta
      781 ttacatctgg caggacgata tgtcgggtcg gttactgttt tccgccctgt tagccgcagc
      841 aaagcgtggc gttcgcgtcc gtttgttgct ggacgacaac aatacgcccg gacttgatga
      901 cattttacgc ttgcttgaca gccatccacg cattgaagtc cggcttttta atcctttctc
      961 gtttcgtttg ctacgtccgc ttggttatat caccgacttt tcccgtctca atcgccgtat
     1021 gcacaataaa agtttcactg tcgatggcgt ggtgacgctg gtgggaggac gaaatattgg
     1081 tgatgcctat tttggggcag gggaagagcc acttttttcg gatttagatg tcatggcaat
     1141 aggacccgtg gtagaggacg ttgccgatga tttcgcccgc tactggtatt gcaaatcggt
     1201 ttccccctta cagcaggtgc tggatgtccc ggaaggtgaa atggcggatc acatcgagtt
     1261 acccgcctcc tggcataacg atgtcatgac gcatcgttac ttacgcaaaa tggaatccag
     1321 tccgtttata catcatctgg ttgatggaac gttgccgctt atctgggcga aaacatgttt
     1381 attaagtgat gatccggcga aaggggaggg caaggcaaaa cggcattcac tgttaccgca
     1441 gcgcctgttc gatatcatgg gctcacccag tgaacgcatc gatattatct cttcctattt
     1501 tgtaccgaca cgtgcaggtg tggcgcaact cttacggatg gtgagaaaag gggtaaagat
     1561 tgcgatccta accaattctc ttgccgctaa cgatgttgct gtcgtccatg ccggatacgc
     1621 gcgctggcgc aaaaaattgc ttcgctatgg ggtggaatta tatgaactca agccgacgcg
     1681 tgaacaaagt agtacattac acgatcgcgg tataaccggt aattccggtg ccagcctgca
     1741 tgctaaaacc tttagcatcg atggtaaaac ggtgtttatt ggctctttca atttcgatcc
     1801 gcgttcaaca ttgctcaata ctgaaatggg cttcgtgata gagagcgaaa cgctggcaca
     1861 gttaattgat aaacgcttta ttcagagcca gtatgatgcg gcctggcagc tccgtctgga
     1921 caggtgggga cggatcaact gggttgatcg tcatgcaaag aaagagatta ttctcaaaaa
     1981 agaacccgcc accagtttct ggaagcgggt tatggtcaaa ctggcgtcga tattgcccgt
     2041 ggaatggtta ttgtaaacgc ggcttaacgg gcaggtgctt tatcgttctc acgcttaaca
     2101 accggtttac cagagaacaa aaacttcaat aatgggatgc gtaaatgaat ttcatacaga
     2161 attatcgcaa tccctactac gaatatcagg ccacagagaa aaccaagcca gttggaggtg
     2221 atgtgtggtg taatgtatgc gccgaaaaac agcgttaacg ggtggtgaac cagatagata
     2281 aacagcgatg cgttaacaaa ataagtcacc cgcgctgact ggaagttaag caaacggtgg
     2341 ccaaaggaga agaccacatt caccatccac agaccgagga ccatggtgat caccgactcg
     2401 gtttcataca tccaggcatc gccactgcca tagcgcaggt tgagtaaata agcgacaaac
     2461 gccaatgctg ctgcaagggt acagccacga gaaggcgtgg taaacaaggc tttaagatga
     2521 gggaaaatga aagccagtgc gccgaggata aagaacggca aataaaataa cgtttgcatg
     2581 acaataaaat tgaacatgcc gttactcaga atgggtggat acacaataaa aatcgttctt
     2641 cttattaccg cataaccgat gccgaggcac aaaaaaatca ccgataattt taccatcgag
     2701 aattttttat tcgttttatc agaattttct aaattatttc tgatgcgttt aaatatccat
     2761 acgcacagcg tcgtcatgac cactaacacc agtaaaaacc acaggtgtga tattaattcc
     2821 caggccaacg tattatattt gtcatacaat gacagcccag gccaactttc cgctttgcct
     2881 ttgacgtatt gcagcataat aaattgcggc aatgtcagta aggggatggc tgttaacatc
     2941 gggataccta cacgttcgac acgtactttc caccattttt tcaagggata gcgtaaaaaa
     3001 agcatgtagg aaaagtaccc ggatataacg aaaaacacct gcatgcggaa cgagtggatg
     3061 aagtcattaa aaagggtcag ccacaatgac ggctcggcgc tattcacatg ccatgtatgg
     3121 ctcgaataga ttaaagaaat atgaaaaggg atccctaaca acatcagcca ggcgcggatg
     3181 gagtcgagga aatattcacg ttgcgcgggt actggattca tatatggtta actgatctca
     3241 gatttttcgt cttatccctg tcgggttatg cctttaggct tgttgccata gtgacaccga
     3301 cctgaccgcg ccaggcgcag gcttcaaggt ttttatgcat agcatcatcg ctaccactaa
     3361 ccagaatgga agcgtctgta agacggttga taaataaatt tgctggcaaa ccctacacga
     3421 agtcgatgct tctgtcttta ggagaagcac ggaaagtgaa aacggttgca atcaggtgct
     3481 taatccatga gccagtgtgc tgaacgatac cgggattctg ttgtcggaat ggcaggttat
     3541 ccattaaaat agatcggatc gatataagca cacaaagggg gaagtgctta ctaattatga
     3601 aacataaact acaaatgatg aaaatgcgtt ggttgagtgc tgcagtaatg ttaaccctgt
     3661 atacatcttc aagctgggct ttcagtattg atgatgtcgc aaagcaagct caatccttag
     3721 ccgggaaagg ctatgaggcg cccaaaagca acttgccctc cgttttccgc gatatgaaat
     3781 acgcggacta tcagcagatc cagtttaatc atgacaaagc gtactggaac aatctgaaga
     3841 ccccattcaa actcgagttc taccatcagg gtatgtactt cgataccccg gtcaaaataa
     3901 atgaagtgac tgccaccgca gtcaaacgaa tcaaatacag cccggattat ttcactttcg
     3961 gcgatgttca gcatgacaaa gacacggtaa aagaccttgg ttttgccggt ttcaaagtgc
     4021 tttacccgat caacagcaaa gataaaaacg atgaaatcgt cagcatgctc ggggccagct
     4081 atttccgcgt gattggtgca ggtcaggttt atggcctttc tgcacgcggc ctggcaattg
     4141 ataccgcctt gccatcgggt gaagaatttc cacgcttcaa agagttctgg atcgagcgtc
     4201 caaaaccgac tgataaacgt ttaaccattt atgcattgct tgactcgccg cgcgcgacag
     4261 gtgcttacaa attcgtagtt atgccaggac gtgacacggt tgtggatgtg cagtcgaaaa
     4321 tctatctgcg cgataaagtc ggcaaactgg gggttgcacc gttaaccagt atgttcctgt
     4381 ttgggccgaa ccaaccgtcg cctgcaaata actatcgtcc ggagttgcac gactctaacg
     4441 gtctgtctat ccatgctggt aatggcgaat ggatctggcg tccgttgaat aacccgaaac
     4501 atttagctgt cagcagcttc tcgatggaaa acccgcaagg cttcggtctg ttgcagcgcg
     4561 gtcgtgattt ctcccgcttt gaagatctcg atgatcgtta cgatcttcgt ccaagcgcat
     4621 gggtgactcc gaaaggggag tggggcaaag gcagcgttga gctggtggaa attccaacta
     4681 acgatgaaac caacgataac atcgtcgctt actggacgcc ggatcagctg ccggagccgg
     4741 gtaaagagat gaactttaaa tacaccatca ccttcagccg tgatgaagac aaactgcatg
     4801 cgccagataa cgcatgggtg caacaaacgc gtcgttcaac gggggatgtg aagcagtcga
     4861 acctgattcg ccagcctgac ggtactatcg cctttgtggt cgattttacc ggcgctgaga
     4921 tgaaaaaact gccagaggat accccggtca cagcgcaaac cagcattggt gataatggtg
     4981 agatagttga aagcacggtg cgctataacc cggttaccaa aggttggcgt ctggtgatgc
     5041 gtgtgaaagt gaaagatgcc aagaaaacca ctgaaatgcg tgctgcgctg gtgaatgccg
     5101 atcagacgtt gagtgaaacc tggagctacc agttacctgc caatgaataa gacaactgag
     5161 tacattgacg caatgcccat cgccgcaagc gagaaagcgg cattgccgaa gactgatatc
     5221 cgcgccgttc atcaggcgct ggatgccgaa caccgcacct gggcgcggga ggatgactcc
     5281 ccgcaaggct cggtaaaggc gcgtctggaa caagcctggc cagattcact tgctgatgga
     5341 cagttaatta aagacgacga agggcgcgat cagctaaagg cgatgccaga agcaaaacgc
     5401 tcctcgatgt ttcccgaccc gtggcgtacc aacccggtag gccgtttctg ggatcgcctg
     5461 cgtggacgcg atgtgacgcc gcgctatctg gctcgtttga ccaaagaaga gcaggagagt
     5521 gagcaaaagt ggcgtaccgt cggtaccatc cgccgttaca ttctgttgat cctgacgctc
     5581 gcgcaaactg ttgtcgcgac ctggtatatg aagaccattc ttccttatca ggggtgggcg
     5641 ctgattaatc ctatggatat ggttggtcag gatgtgtggg tttcctttat gcagcttctg
     5701 ccttatatgc tgcaaaccgg tatcctgatc ctctttgcgg tactgttctg ttgggtgtcc
     5761 gccgggttct ggacggcgtt gatgggcttc ctgcaactgc ttattggtcg cgataaatac
     5821 agtatatctg cgtcaacagt tggcgatgaa ccattaaacc cggagcatcg cacggcgttg
     5881 atcatgccta tctgtaacga agacgtgaac cgtgtttttg ctggcttgcg tgcaacgtgg
     5941 gaatcagtaa aagccaccgg gaatgccaaa cactttgatg tctacattct gagtgacagt
     6001 tataacccgg atatctgcgt cgcagagcaa aaagcctgga tggagcttat cgctgaagtc
     6061 ggtggcgaag gtcagatttt ctatcgccgc cgccgccgtc gcgtgaagcg taaaagcggt
     6121 aatatcgatg acttctgccg tcgctggggc agccagtaca gctacatggt ggtgctggat
     6181 gctgactcgg taatgaccgg tgattgtttg tgcggcctgg tgcgcctgat ggaagccaac
     6241 ccgaacgccg ggatcattca gtcgtcgccg aaagcgtccg gcatggatac gctgtatgcg
     6301 cgctgtcagc agttcgcgac ccgcgtgtat gggccactgt ttacagccgg tttgcacttc
     6361 tggcaacttg gcgagtcgca ctactggggg cataacgcga ttatccgcgt gaaaccgttt
     6421 atcgagcact gtgcactggc tccgctgccg ggcgaaggtt cttttgccgg ttcaatcctg
     6481 tcacatgact tcgtggaagc ggcgttgatg cgccgtgcag gttggggggt ctggattgct
     6541 tacgatctcc cgggttctta tgaagaattg ccgcctaact tgcttgatga gctaaaacgt
     6601 gaccgccgct ggtgccacgg taacctgatg aacttccgtc tgttcctggt gaagggtatg
     6661 cacctggttc accgtgcggt gttcctgacg ggcgtgatgt cttatctctc cgctccgctg
     6721 tggtttatgt tcctcgcgct ctctactgca ttgcaggtag tacatgcgtt gaccgaaccg
     6781 caatacttcc tgcaaccacg gcagttgttc ccggtatggc cgcagtggcg tcctgagctg
     6841 gcgattgcac tttttgcttc gaccatggtg ctgttgttcc tgccgaagct attgagcatt
     6901 ttgcttatct ggtgcaaagg aacgaaagaa tacggcggct tctggcgcgt tacattatcg
     6961 ttgctgctgg aagtgctgtt ttccgtgctg ctggctccgg tacgcatgct gttccatacg
     7021 gtcttcgtcg tcagcgcgtt ccttggctgg gaagtagtgt ggaattcgcc gcagcgtgat
     7081 gatgactcca cttcctgggg ggaagcgttc aaacgccacg gctcacagct gctgttaggg
     7141 ttagtgtggg ctgttgggat ggcgtggctg gatctgcgtt ttctgttctg gctggcaccg
     7201 attgtcttct cgttgatcct gtcaccgttt gtttcggtga tttccagccg tgccaccgtt
     7261 ggtctgcgaa ccaaacgctg gaaactgttc ctgatcccgg aagagtattc accgccgcag
     7321 gtgctggttg ataccgatcg gttccttgag atgaatcgtc aacgctccct tgatgatggt
     7381 tttatgcacg cggtgtttaa cccgtcattt aacgctctgg caaccgcaat ggcgaccgcg
     7441 cgtcaccgcg ccagcaaggt gctggaaatc gcccgtgacc gccacgttga acaggcgctg
     7501 aacgagacgc cagagaagct gaatcgcgat cgtcgcctgg tgctgctaag cgatccggtg
     7561 acgatggccc gtctgcattt ccgcgtctgg aattccccgg agagatattc ttcatgggtg
     7621 agttattacg aagggataaa gctcaatcca ctggcattgc gtaaaccgga tgcggcttcg
     7681 caataaaaac gtagttgcct gatgcgctac gcttatcagg cctacatcgt tcctgcaatt
     7741 tattgatttt gcaagatttt gtgggtctgg caaggcgttc acgccgcatc cggcaaaaac
     7801 aacgagccaa taaaaatacc ggcgttatgc cggtattttt tacggaagag gtatcaaatg
     7861 cgtttaattg tggtgagcat aatggtgacc ttgctgagtg gctgtggcag catcattagt
     7921 cgcactatac cggggcaggg gcatggcaac caatattatc ccggtgtgca atgggacgtg
     7981 cgtgactccg cctggcgtta cgtcacgatc cttgatctgc cattctccct ggttttcgat
     8041 accttactgc tgccgatcga cattcatcat ggcccgtatg agtgattaac gttcatccca
     8101 ctcatcagct gctgtgcgtc cttcctcggt atccagcggt ggctcaagct gaaattcccc
     8161 ctcgtcccat tcatgtaatg tattctcatc ttgccactcc tggcggatct ctatctcatc
     8221 atagtcgccg tcaaagacac tttgcgcagc ttcaccgcta agcatgggta aacattcacc
     8281 ttcttcccct tcgtcggcaa aaaactcaac ttgccacatg atgtcgccgt cctgcaaaac
     8341 gtatttttgg gcattgaact gttgcacatt cgcgttttcg gcgtcgatgc cggggttgtc
     8401 tgcaagaaat tcttcgcgtg cagcgtcaat ggcttcttca agcgttgcgt acatggtcat
     8461 cacgattctc cctttgagtt gatgaggttt cagggaaaag gatagctgat tctccgcttt
     8521 tgcaagtatg aaaggcgaaa aatcagttcg atatctgggg gattcgacga cgacgtagac
     8581 tgttccatga atagactgcg ttgaataaca ctacgccagc ggtgacgaga aataccgccc
     8641 taaaaccgta gttcgctgaa atcgctgctc ccatcaatgg tccggtaacg ttgccaatat
     8701 cacgaaacga ttggttatag ctgaagatac gcccggcgat ctggttgctc gagttataaa
     8761 ctaatagtgt ctgtacggcg gggagtagtg caccatcggc ggcaccgagc aaaaaacgta
     8821 aaatcccaag ttgcaatggc gtctgaacgt aagacattgg gatcaacagc agtacagaaa
     8881 agatcagcgc cgtaatcagg atcttttcgg gtccgattcg atcgccaagt ttgccgagtc
     8941 gtggtgcact tagcagagcc gccacgcctg gcaccgaggc gatcatgcca ctgataaagg
     9001 cgacgttact gacgttaccc gccagttcgc ggacatacag cgtcagaatg ggggcaattg
     9061 agcccgtcgc cacctggatg attaacgtgg tgacaaacag gctgagtacc agtttcgggt
     9121 ttttaagtga tgtcaccact tcccgcatgt gcagcatctc ttttttgctg accggctgga
     9181 atttttctct gatgcaaaac agggtgacga aaaagcagag tatgagcaca ctggcggtaa
     9241 taaagaatac cggacgtaag ccgtagctat cggcgagcaa accgccagcc attgggccga
     9301 gcaacgcgcc gctaacgccg cctgtggaga gcgtacccag cgcccagccg cttttattac
     9361 gcggtacttg tgtggcgata agagcattag cgttggggac aaatccgcca agtaaaccaa
     9421 gaagcgcccg caggatcaaa aactgccaga tattttgtgc cagtcccatc aacaccatca
     9481 cgatgcccat gccgagagca gagcgtaata gcatgagttt tcggccttta cgatcggcga
     9541 gtccacccca aaacggtgag gcgatggccg aaaataaaaa tgtaatgctg aagacaatac
     9601 cggaccacat attcagggcg gagtggccgg taacgccaag ctgctcaacg tagaggggta
     9661 agaagggcat taccaggctg aaggcggcac cggtaagaaa acagcctagc caggcgacga
     9721 tcaggtttcg tttccagttt ataggggtgt cattttcaca gggtgacata gcaatccgct
     9781 gttggtgcgc caggcgcggt gaacataaga agaaaagata agcacactaa ttatgcgccc
     9841 gacttccagg gggcgcaatc cagagagctt ttatcgctaa atcaggggga ttttctgtgg
     9901 taatgccgga tgccattctg aagcatccag catggaagat ttaatagcgt gaaggaacgc
     9961 cttccgggcg tgttttaaag cgacggtgta accacatata ctgctctggt gccatcatga
    10021 tgcatttttc gaccactttg ttcatccacg cggcggtagt ttcggcatca tccagcggcg
    10081 gagaacactc tggcggcagt ataatcaact gatacccttt gccatctggc ttacggcgtg
    10141 gaacgaaggg caccagacat gcgccggaca tccgtgccag catccaggtt ccggtcgtgg
    10201 tcgcagcctg ctcaacggca aacaacggga cgaaaacgct tgagcgcggg ccgtaatcat
    10261 gatccggtgc gtaccagacc acttcgcctt ttttcagggc tttaatcatg ccttttaaat
    10321 ctttgcggtc gagcatcgat ttatttgagc gcaaacggcc ccaggtttgt agccagtcaa
    10381 tcagtggatt atcgttcggg cggtaaacgc caatccccgg ttcctgcata ccaaactgcc
    10441 gcgcacccag ctccagtgtc agaaaatgga tgccaactaa caggatgccg cgtttttgcg
    10501 cctgcacgtc acgaatgtgt tccatgccga tcacttccgt ccagcgggcg attcggcggt
    10561 ccggccagaa ccacgccatg ccggtttcca tcaggcccat gccaacggat tcgaaattct
    10621 tcaccaccat tttacggcgt tcttgttcgc tcatttccgg gaagcacagt tccaggttgc
    10681 gatgcacaat ttttgcgcgt cgtttcataa aacgtaacgc cagttttcct aatccacaac
    10741 cgaggcggta gataaccggg tagggcaatt gcacgaccaa ccaaagtacg ccaataccca
    10801 accaggttaa ccaataacgc ggatgaagca gtgcggtgga gaacttgggt agattcgtca
    10861 tatcaatcct gtttttcaac ctatacgggc aattgtatgt attgtcgcat tttttcgtcc
    10921 gcaaccaaaa tttgtgactg aagactgggc gaaattgccg cgcttgtaaa taacaaataa
    10981 tttttaatgc taaaatgtag cgtaaaatgt gtggatgtta attatcgata attgctatat
    11041 catgccgcgg atttttactt tcccatctcg caggaaccgt acaccatgcc agtgttacac
    11101 aaccgcattt ccaacgacgc gttaaaagcc aaaatgttgg ctgagagcga accgcgaacc
    11161 accatttcgt tttataagta tttccacatt gccgatccta aggtgacccg tgacgcttta
    11221 tatcaactgt ttaccgcgct gaatgttttt gggcgagtgt atctggcgca tgagggcatt
    11281 aacgcgcaaa tcagcgtacc tgcgagcaat gttgaaacat ttcgcgcaca gctctatgcc
    11341 ttcgatccgg ctttagaggg tttacgcctg aatatcgcgt tggatgatga cgggaaatcc
    11401 ttctgggtac tgcgtatgaa ggtacgcgat cgcattgttg ccgacggtat tgacgatcct
    11461 cactttgatg ccagcaatgt tggtgagtat ctgcaagcgg cggaagtgaa cgccatgctt
    11521 gacgatcccg atgcattgtt tatcgacatg cgtaaccact atgagtatga agtggggcac
    11581 tttgaaaacg cgctggaaat accggcagat accttccgtg agcagctgcc aaaagcagtt
    11641 gagatgatgc aggcacataa agataaaaaa atcgtcatgt actgcaccgg cggcattcgt
    11701 tgtgaaaagg ccagtgcctg gatgaaacat aacggattca acaaagtctg gcatatcgag
    11761 ggcggaatta ttgaatacgc ccgtaaggcg cgcgagcagg gcttgccggt gcgttttatt
    11821 ggcaaaaatt ttgtttttga cgagcggatg ggcgaacgta tatctgatga gattatcgcg
    11881 cactgccacc agtgcggtgc gccgtgcgac agccatacca actgtaaaaa tgatggctgc
    11941 catctgctgt ttattcagtg tccagtatgt gcggaaaaat acaaaggttg ttgtagtgag
    12001 atttgctgcg aagaaagcgc gttaccgcca gaggaacagc gacgccgtcg ggcaggacgt
    12061 gaaaatggca ataagatctt taataagtct cgtggacgtc tgaatacaac actgggcatt
    12121 cctgatccaa cagaataaat atcattgccg gatgcgtgcc atccggcaac atttcactct
    12181 tacttctgct gtacgccttc cactgaaata atcagatcca cttcctgaga cgctggacct
    12241 aaatctgtct tgatattgaa gtctttgagc ttaattttgc cttcggcctc aaagcctgca
    12301 cgtttaccgc cccacgggtc gtcaccctga ccaattaatt tcgcttccag tgtgacgggc
    12361 ttggttacac cattcagcgt cagattgccg gtaatatcca gttcgtcacc gtctttcttc
    12421 acgctggtgg aggtgaatgt tgcctgtgga tattttgcgg tattgaggaa atccgcactg
    12481 cgaagatgtt tatcgcgttc ggcgtgatta gtatcgacgc tggtggtgtt aattgtcaca
    12541 ttcactttat cggcagctgg atttttttca tcaaaggtaa aagtaccgtc gaaatctttg
    12601 aaggtgccat ataaccagct atagccaaga tgctggattc ggaagttaac aaaggcgtgc
    12661 tgaccttctt tgtcaatttt gtaatcggcg gcaaccgctg aaccggcaga gaacatcaag
    12721 gaagcgaagg ttaaaccaag caggcttttt ttcatttttt atactccata gtcagatgac
    12781 gactttccca gcatgcgctt cagagtgtcg tctttatcga tgaaatgatg cttcagggcc
    12841 ataaatccgt gcataacgga cagtactaca acgctccacg cgagccaaaa atgcagggca
    12901 ccggcaaagt cagcctgtgc gccagcgtcg gagagggtcg cggggacgtc aaaccagcca
    12961 aaaacgctga tcggtttacc atcggcagtt gagatcagat agccgctgat gccgatggcg
    13021 aacagcaata ggtacaatgc gagatgtcca gcttttgctg caagacgagt catgggcgaa
    13081 taactcggca gcggacccgg cggtggagat atgacacgcc acagaacgcg aataaccagc
    13141 cccatcatta acaaaatacc gatgctttta tgcagttcgg gtgctttgtg ataccagcca
    13201 tcgtaataac tgagcgtgac catccacaga cctaaagcaa acatgccgta gacaataatt
    13261 gcgcttagcc aatgtaaggc cgcagatata acaccatagc gttcaggggt atttgtgaat
    13321 gacataagta catccaaaac gaatttgcga gagaaagaaa atggcgtgtc ggagaatgaa
    13381 ttgcaacaca aaaataacaa attgaatgat atttattttt atttcaataa ttttgaatta
    13441 ataatgaaag aatcttcata agtttagtgg gttaagcatc tggaaggtc
//
LOCUS       DAPOXO010000116        13455 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.116, whole genome shotgun sequence.
ACCESSION   DAPOXO010000116 DAPOXO010000000
VERSION     DAPOXO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13455
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.116"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            49..2277
                     /gene="crfC"
                     /locus_tag="ROH59_004415"
     CDS             49..2277
                     /gene="crfC"
                     /locus_tag="ROH59_004415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
                     /protein_id="HDX4806819.1"
                     /translation="MYTQTLYELSQEAERLLQLSRQQLQLLEKIPLSVPGDDAPQLAL
                     PWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPM
                     TALPTLIRHTPGQKEPVLHFSHVAPIDHLIQQLQQRLRDCDIKHLTDVLEIDKDMRAL
                     MQRIENGIAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVE
                     FVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISD
                     EEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVS
                     SMWGYLANRARHELANNGKLPAPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQ
                     LWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQ
                     LRQNIHQVEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDAVNAQLAALFQD
                     NSESLSEMRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELS
                     ESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTRLGVVREIFSRWLNQPD
                     WGRGNEKFPTETVDYSVLQRALSAEVDLYCQQMAKVMAEQVDESVTAGMNTFFAEFAS
                     CLTELQTRLRESMALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAE
                     RY"
     gene            2274..3152
                     /locus_tag="ROH59_004416"
     CDS             2274..3152
                     /locus_tag="ROH59_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcZ-like family protein"
                     /protein_id="HDX4806820.1"
                     /translation="MTKTLLDGPGRVLESVHPRFLVDLAQGDDARLPQAHQQQFRERL
                     MQELLARVQLQTWTNGGMLNAPLSLRLTLVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRQHSAFPELPQQIVALYEWFSARCRWKEKALTQRGLLVQAGEQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLRVKATQHLAESINAAPTTR
                     HYYHQWFASSTVSTGGDHADFLSWLGKWSTADKQPVCWSVTQRWRTVALGMPRLCSAQ
                     RLAGAMVEEIFSVNLV"
     gene            3416..4918
                     /gene="proP"
                     /locus_tag="ROH59_004417"
     CDS             3416..4918
                     /gene="proP"
                     /locus_tag="ROH59_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HDX4806821.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE"
     gene            5030..5119
                     /gene="pmrR"
                     /locus_tag="ROH59_004418"
     CDS             5030..5119
                     /gene="pmrR"
                     /locus_tag="ROH59_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HDX4806822.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFATY"
     gene            complement(5095..6195)
                     /gene="pmrB"
                     /locus_tag="ROH59_004419"
     CDS             complement(5095..6195)
                     /gene="pmrB"
                     /locus_tag="ROH59_004419"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HDX4806823.1"
                     /translation="MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIDAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWIRLKKDQYVANQI"
     gene            complement(6196..6864)
                     /gene="basR"
                     /locus_tag="ROH59_004420"
     CDS             complement(6196..6864)
                     /gene="basR"
                     /locus_tag="ROH59_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HDX4806824.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            complement(6861..8504)
                     /gene="eptA"
                     /locus_tag="ROH59_004421"
     CDS             complement(6861..8504)
                     /gene="eptA"
                     /locus_tag="ROH59_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HDX4806825.1"
                     /translation="MLKRLLKRPSLNLFSWLLLATFYISVCLNIAFFKQVLQVLPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLGSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMITNIIDTTPAESYALMTPRMLLTLGLSGVLAAIIACWIKIKPTTSRLRSVLFRGAN
                     ILISVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRSANLPLIR
                     IGEDAHRNPLMQNGKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGVCD
                     RVPHQNVTALNLPGQCINGECYDEVLFHGLEDYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCTQEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            complement(8608..9945)
                     /gene="adiC"
                     /locus_tag="ROH59_004422"
     CDS             complement(8608..9945)
                     /gene="adiC"
                     /locus_tag="ROH59_004422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HDX4806826.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            complement(10082..10843)
                     /gene="adiY"
                     /locus_tag="ROH59_004423"
     CDS             complement(10082..10843)
                     /gene="adiY"
                     /locus_tag="ROH59_004423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AdiY"
                     /protein_id="HDX4806827.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFLSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
     gene            complement(11179..13446)
                     /gene="adiA"
                     /locus_tag="ROH59_004424"
     CDS             complement(11179..13446)
                     /gene="adiA"
                     /locus_tag="ROH59_004424"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HDX4806828.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKINESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEITPREAYNAIVDNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
BASE COUNT         3259 a         3268 c         3541 g         3387 t
ORIGIN      
        1 atctggctaa ataaaagtaa taaaatttgc tttaaggaag aatattctat gtacacacag
       61 accctgtatg agttaagtca ggaggctgaa cgcctgttac agctttcccg acaacagttg
      121 cagttactgg aaaaaatacc tctctctgta cccggagacg atgcgccaca actggcttta
      181 ccctggagtc agcctaatat cgccgaacgt cacgcgatgc tgaataatga gttgcgtaaa
      241 atttcccggc tggaaatggt gctggcgatt gtcggtacca tgaaagcagg gaaatcaacc
      301 accattaatg ccattgttgg tacggaggtt ctgcctaatc gcaatcgccc aatgactgcg
      361 ctgccaacgc ttattcgcca tacgcccggg caaaaagaac cggtactgca tttttcacat
      421 gtcgcgccaa tcgaccattt aattcaacaa ttacaacagc gcctgcgtga ttgcgatatt
      481 aagcatctga ccgatgtgct ggaaatagat aaagatatgc gtgcgcttat gcagcggatc
      541 gaaaatggca tcgctttcga aaaatattat ctgggtgctc aacctatttt tcattgtctg
      601 aaaagtttga atgatttggt gcgactggcg aaggcgctgg acgtcgattt tcctttttct
      661 gcttacgccg ccattgagca tattcccgtg attgaagtgg agtttgtcca tctggcgggg
      721 ctggagagtt atcccggtca gttgacgtta ctggataccc ccgggccaaa tgaagccggg
      781 caaccgcatc tgcaaaaaat gcttaaccag cagctggcac gcgcctcggc ggtactggcg
      841 gtgctggatt atacgcaact gaaatcgatc tccgatgaag aggtccgtga ggcaattttg
      901 gcggtggggc aatcggtgcc gttgtatgtg ctggtcaata agttcgatca acaggatcgt
      961 aacagtgacg acgccgacca ggtgcgggca ctgatttccg gaacgctgat gaaaggctgt
     1021 attacgccac agcagatatt tccggtgtcg tcgatgtggg gctacctggc gaatcgggcg
     1081 cgccatgagt tagccaacaa cggtaagtta cccgcgccag agcaacaacg ctgggtggaa
     1141 gattttgccc atgccgcgct cggcaggcgc tggcgtcatg ccgatctggc ggacctcgaa
     1201 catattcgcc atgctgccga tcagttgtgg gaagattcgc tgttcgccca gccaattcag
     1261 gcgttgcttc atgccgctta cgctaacgcc tcgttgtatg ctctgcgatc tgccgcgcat
     1321 aaactgttga attacgcgca gcaggcgcgg gaatacctgg attttcgtgc gcacgggtta
     1381 aacgtcgctt gtgaacaatt gcggcaaaat atccatcagg tcgaagaaag tttgcagcta
     1441 ttgcaactca atcaggcgca ggtgagcggc gagattaaac atgaaatcga gttggccctg
     1501 acctccgcca accactttct gcgtcaacag caagatgcgg tgaatgcgca gttagccgcg
     1561 ttgtttcagg ataattcgga gtcgttaagt gagatgcgta cccgctgtga gacactgtta
     1621 cagacggcgc agaacaccat cagtcgcgac tttacgctgc gctttgccga gcttgagtcc
     1681 accctttgcc gggtgttaac cgatgttatt cgccccattg agcaacaagt caaaatggaa
     1741 ttgagtgagt ctgggtttcg tcctgggttt cattttcctg tttttcacgg cgtagttccc
     1801 cacttcaaca cccgccagct gttcagtgaa gtcatttcgc gccaggaagc aacggacgag
     1861 cagagcacgc gtttaggcgt tgtgcgtgag attttttcgc gctggttgaa tcagcccgac
     1921 tggggacggg gaaatgagaa attcccgaca gagacggttg attacagtgt gttgcaacga
     1981 gcattaagcg cagaagtcga tctttattgc caacaaatgg ctaaagttat ggcagagcag
     2041 gtcgatgaat ctgttacggc aggcatgaat acttttttcg ctgagttcgc ttcatgtttg
     2101 acggaattac agacgcgttt acgcgaaagt atggctctgc gtcaacaaaa tgaatcggtg
     2161 gtcaggctga tgcaacagca attgcagcag actgtgatga ctcacggctg gatttacacc
     2221 gacgctcagc tgttacgcga tgatattcaa acacttttca cggcagaacg atattgacca
     2281 agacgttact ggacggcccc ggtcgcgtgc tggagtcggt tcatccgcgc tttttagtgg
     2341 atctggcgca gggcgatgat gcccgccttc cacaagccca tcagcagcag tttcgtgaac
     2401 gactgatgca ggaacttctt gcgcgcgtgc agcttcagac atggacgaac ggcggcatgt
     2461 taaatgcgcc gcttagcctg cgtctgacat tggtggaaaa actggcgtcg atgctggatc
     2521 ccggtcatct ggcgctgacg cagatcgcgc agcatctggc gctgctgcaa aaaatggatc
     2581 accgccagca ctctgctttc ccggagctcc cccagcaaat tgtcgccttg tatgagtggt
     2641 tttcagcccg ttgtcgctgg aaggaaaagg cgttaacgca acgaggccta ttggtgcagg
     2701 cgggtgaaca gagcgagcaa atttttaccc gctggcgtgc tggggcgtat aacgcctggt
     2761 cgttgcctgg gcgctgtttt atcgttctcg aagagttgcg ctggggtgca tttggcgatg
     2821 cctgccgtct gggaagcccg caagcggtgg cgttgttgct aggtgatttg cgcgtgaaag
     2881 cgacacaaca tttggcagag agtatcaatg cggccccgac cacgcgtcac tattaccatc
     2941 agtggtttgc ctcttcgacc gtttcgacgg gcggggatca tgctgatttt ttaagttggc
     3001 tgggaaagtg gtctacggca gataaacaac ccgtttgctg gtcagtgacc caacgctggc
     3061 gaactgtcgc actggggatg ccacgactct gttcagcgca gcgtctggcg ggggcaatgg
     3121 tcgaggaaat cttctctgta aatttggtgt aaataatcag ttacaccaat gagtcctaaa
     3181 cgaaatgcat gtgtgaagtt gatcacaaat ttaaacactg gtagggtaaa aaggtcatta
     3241 actgcccaat tcaggcgtca actggtttga ttgtacattc cttaaccgga gggtgtaagc
     3301 aaacccgcta cgcttgttac agagattgca tcctgcaatt cccgctcccc ttttgcggcc
     3361 gtcgcgctga tttttctggc gtttgcggaa atgggccaac tctgcgagga aagctatgct
     3421 gaaaaggaaa aaagtaaaac cgattaccct tcgtgatgtc accattattg atgatggtaa
     3481 actgcgtaaa gccattaccg cagcatcact gggtaatgca atggaatggt tcgattttgg
     3541 tgtttatggt tttgttgctt acgcattagg taaagttttt ttcccggggg ctgaccccag
     3601 cgtgcagatg gttgctgcac tcgccacttt ctccgttccc tttctgattc gaccgcttgg
     3661 cgggctcttc tttggtatgt tgggcgataa atatggtcgc cagaagatcc tcgctatcac
     3721 tattgtgatt atgtcgatca gtacgttctg tattggctta ataccgtcct acgacacgat
     3781 tggtatttgg gcaccgattc tgctgttgat ctgtaagatg gcacaaggtt tctcggtcgg
     3841 cggtgaatat accggggcgt caatatttgt tgcggaatac tcccctgacc gtaaacgtgg
     3901 ctttatgggc agctggctgg actttggttc tattgccggg tttgtgctgg gagctggcgt
     3961 agtggtgtta atttcgacca ttgtcggcga agagaacttc ctcgattggg gctggcgtat
     4021 tccgttcttt atcgctctgc cgttagggat tatcgggctt tacctgcgcc atgcgctgga
     4081 agagactccg gcgttccagc agcatgtcga taaactggaa cagggcgacc gcgaaggttt
     4141 gcaggatggc ccgaaagtct cgtttaaaga gattgccacc aaacactggc gcagcctgtt
     4201 gacatgtatt ggtctggtaa ttgccaccaa cgtgacttac tacatgttgc tgacctatat
     4261 gccgagttat ttgtcgcata acctgcatta ctccgaagac cacggggtgc tgattattat
     4321 cgccattatg atcggtatgc tgtttgtcca gccggtgatg ggcttgctga gtgaccgttt
     4381 tggccgtcgt ccgtttgtgc tacttggtag tgttgcactg tttgtgttgg cgatcccggc
     4441 gtttattctg attaacagta acgtcatcgg cctgattttt gccgggttac tgatgctggc
     4501 ggtgatcctt aactgcttta cgggcgttat ggcttctacc ttgccagcga tgttcccgac
     4561 gcatatccga tacagcgcgc tggcggcggc atttaatatt tcggtgctgg ttgccggtct
     4621 gacgccaaca ctggcggcct ggctggtcga aagctcgcag aatctgatga tgcctgccta
     4681 ttacctgatg gtagtggcgg tggttggttt aatcaccggc gtaaccatga aagagacggc
     4741 aaatcgtccg ttgaaaggtg cgacaccggc ggcgtcagat atacaggaag cgaaggaaat
     4801 tctcgtcgag cattacgata atatcgagca gaaaatcgat gatattgacc acgagattgc
     4861 cgatttgcag gcgaaacgta cccgcctggt gcagcaacat ccgcgaattg atgaataagc
     4921 tgaaacggat ggcctgatgt gatgctgtct tatcaggtca attgaactct taaggttcac
     4981 ttaatctctg acgcgcatac tctcctccag gttaacggag gagagtgcaa tgaaaaaccg
     5041 tgtttatgaa agtttaacta ccgtgttcag cgtgctggtg gtcagcagct ttctttatat
     5101 ctggtttgcc acgtactgat cttttttcag ccgtatccag gcccgcgtgc cggaagtctc
     5161 ttgtcggttt tgcaggaaaa actgcccgtg atgcaactgt gtaatgcggc tgacaatact
     5221 taaccccaga ccaattccgc cataacggct gtccattcgt acaaatgctt tactcaactc
     5281 cccgcattta ctctcatcaa tacccggtcc ttcatcttca acggccatga ccgctccgcc
     5341 atcttcttgc agcttaatca taatgttgct gccttgcggg ctataacgat gggcgttttc
     5401 taccaggttt cgcaataaca tccgcagcag ggttgcatca ccctgaacgg tgatgtcggc
     5461 ggcgctctct ggcaatagca gggtttgctg gcgctggtcg agcatggtac tgagttcgtc
     5521 atacgagggg agaatgacat cttccagcag ttttacatgt tgataattac cggaagaaaa
     5581 tgactgtccg gcacgcgcca gttgcagcaa ctgggagacg ctctccatca tctgatcaag
     5641 tcgtgccact aacggtgcta catcaatgtg atgcgttttc gccagcagtt ccagatgcaa
     5701 acgcaccccc gccagtggcg ttcgcagttc gtgcgcgacg tcagcggtaa acaacctttc
     5761 attatcgagc gtgctggtca ggcgactgac cagatcgttt aacgccgaaa ccaccgcatc
     5821 gatttcgagg gtggcgctat gaatggcaat gggcgttaag ttgtcggcgg tgcgcgcttc
     5881 cagctctttt tgcagctccg ccagcggtcg ggtgatgcgg cgtaccgcct gatagcagat
     5941 aaatagcgtc aggctaacca taaagacgcc ggggacaatc aggctggcga ccgcctcgcg
     6001 gatctcacgc atgatgtggc gatcgttgtt gcgattgtcg cgtagcgcct gctcaaacag
     6061 ctgaatctgc tcggtacttt catgccatag ccagaagacg ctgatcagct caaacaccaa
     6121 caaaatggcc ccgatggtca atatcagccg ttggcgcagc gatattggtc ggcgcagaaa
     6181 acgcatcaga ttcaattagt tttcctcatt tgcgaccagc atatagccaa atccgcgcac
     6241 ggtgcggata cgggctttgc ccactttgtc gcgcaggtta tggatatgca cttccagggt
     6301 gttggtcgag ggctcgttgt cccagttgta gatatcgttg tagagaattt cccgatgcac
     6361 cgggctgcct gctttaagca tcaggcgcga cagcagagca tattctttgg gcgtcagaat
     6421 caactcttca ccgcccatcc agacctgacg gcgacccata ttcagcgtca ggttgccaac
     6481 aatcagctca ctttcgccct gattattatg gcgtcgtagc agggcgcgga tacgggcgtg
     6541 caactcttcc agcgcaaaag gcttcaccag ataatcgtcg gccccgacat ccagcccggc
     6601 gattttgtcg gtaagggtat cgcgggcggt gagaattaac accggcagag tgtatttttt
     6661 ctgccggata cgggcaagaa aatgcagccc atcttcatcg ggtaagccta aatccagtac
     6721 caccaggctg taatgaccgg cttcaaggct ttgttccgcc atccgcgcgg tgctcacgcc
     6781 atcgcacgcg tagccttcgg tttgcgccgc cagaatcaat ccctgcaata acagcgtatc
     6841 gtcttcaaca atcagaattt tcattcactc actctcctgc aagtttgcag aatatcatcc
     6901 gcagcctggt aatacttcgt ctcaacgcca gtcaggccca ataaggttga gaataaattg
     6961 tcttgtgaat agtgttgcgt ttgcgcctgt ttttgcaggc agttctggtc aacctgatac
     7021 cgtttttgat aatcctccga tagccacagc agcatcggca cctgtttttg gctatccggg
     7081 gcgatggcat aaggcagacc gtgcagatag atgccatttt cacctaacga ttcaccgtgg
     7141 tcagaaagat aaaccaggct ggtggtaaat ttatcctgat gttctttcag cagattaatc
     7201 gctttatcaa caatatagtc gacgtaaacc agcgtgttgt cgtaagtgtt caccagttgc
     7261 tcttgggtac aggtctggat ctcgttagtg tcgcaggttg gggtaaattt cctgaactgc
     7321 ggcggatagc ggttgtaata ggtcgggccg tggctgccga tggtgtgtaa gacaatcacg
     7381 ccatcaccct gcaggttatt gatgtaatct tccagcccgt ggaacagcac ttcatcatag
     7441 cattcgccgt tgatgcactg accaggcagg ttcagcgcgg tgacgttctg gtgaggtacg
     7501 cgatcgcaaa cgcctttaca gccgccatcg ttgtcattcc acagcacgtt gatgcccgct
     7561 cgctgaatga tatccagcac gccttcctgg tgctgtgcca gctcttcttt gtagtgctca
     7621 cgcggcatat ccgagaacat gcatggtact gaaactgccg ttgccgtgcc gcaagaggcg
     7681 gtattaggga aatagaccac gttatctttt gccagacgag gattggtttc gcgtggataa
     7741 ccattcagcg agaaattctc tgcgcgcgac gtttctccga cgatcaaaat ggtcaggttt
     7801 ttacgtttcc cattttgcat taatgggttg cggtgagcat cttcaccaat gcgtatcagt
     7861 ggcaggttgg ctgaccgctg gtgagagtac cacgaccagc tagcaacaat gctgttggac
     7921 gggcttaagg atttcaccag ttctttgttg ttgcgaaaca gcgaggcata gtctttgtag
     7981 aacagtgcgg caaccagcag aatcagcagt acagaaatca ggatgttggc cccgcggaaa
     8041 agaacgctgc gcaggcgtga ggtggtgggt ttgattttga tccagcaggc aataatcgcg
     8101 gctaatacgc cacttaaccc cagcgttaat aacattcgtg gcgtcatcag ggcataactt
     8161 tccgccggcg tagtatcaat gatattggtg atcattgaac ggtcgatgac gatgccatag
     8221 gtcatgatga aatattgcgc agccgcaccg accagaataa acaggcaggc gagtggacga
     8281 ttaagccata agaaagagcc tagtgtcagg acaatattaa tcacgctgaa tgcgacgacc
     8341 ggcatcgaca agaaaaccag cacgttatgc agtgaatcca gcggtaacac ctgtagcacc
     8401 tgtttaaaaa aggcgatatt caggcagact gagatataaa aagtagcaag taataaccag
     8461 gagaataaat tcaaagaggg tctttttagt aggcgcttca acatcacggt gtttccatcg
     8521 aacaaagtgc gcatatgctc gcaaagcaaa attaagccaa ccttaagttc ttaaggttgg
     8581 cttttatgtt tgctggatta aggggaatta atctttgctt attggtgcat ctaagggata
     8641 cgggttttta tgcagccggt tgtaattcag cgcatacatg gcggtgatta ccatcagagt
     8701 gacaaatgac cacataacct ctttcgcgcc ggaccctact acggcccaga tgcagtagag
     8761 gaaggcaatg gtagtaactg ccaggtatgc cgggcgcgct ttaccaaagt gaccgtggcc
     8821 gagcagcagt aacgccgcac aggtgtaaag atatggcacc agtgtaaaga tgaccgacac
     8881 ggaagaaacc agaccgaatt ctttggtcgc gtttggcgaa atgctactga gctggaagat
     8941 ggtcatcaaa ataccgacga taatcagccc cgccactggc gtgcccgctt tatttacacg
     9001 ggcaaaaatc ggtgggaaca gtccgtcatc ggcagcggct ttcgccgttt gacctgccag
     9061 caacgtccag ccgcccagtg aacctaagca acccgcagct gcgcagaagg aaacaatggc
     9121 cccggcggtg tcacccaacg ccatccgtgc ggcatcaccg aatggcgaag cagaaacgcg
     9181 cagtgcggca ttagggatca tccccataat cgcggtggta gaaagtacat agcaaacggc
     9241 agcaatcaat accccgccaa tggtggcgat agggacgttg cgtttcgggt ttttcaccac
     9301 acctgcggca acggaggcac tttccacacc gatgaacgac cacagcgtaa cgttaagggt
     9361 actttgaatc gcaccgaagg tgcccaggcc gctgacgttc catgccgcca tataggtttc
     9421 accacggaac cagaaccagc caaatacggc aatcccgacg atggggatca gcgccagcac
     9481 ggtagcaacg gcctgtacgc gggtgatcat tttcggaccg acaatgttca gcaggacgaa
     9541 gatccacagc accacgacgc aggtgatggt taataccaat ggatctttca gaatcgggaa
     9601 gaagtaactt aaatatccta cgccaatgac caccatggcg atattgccga tccagcaggc
     9661 cagccagtag aggacgttgg tttgataacc gagaaacggc ccaaagcagc ggcgggcgta
     9721 agcgtaagaa ccaccaggac ttgggtcgag gaacgacatt ttggcgtata ccatcgagag
     9781 ccccagcgca ccgataatcg tcaccaacca tccataaatg gcaatcccgc cagtggaggc
     9841 caggtttgca ggtaacagaa aaacacctga ccccataata ttccccgaca ccatcagggt
     9901 gacggggatt aagcccactt tgtgagcatc agcatccgaa gacataatta aactcctgcg
     9961 aaggcgagct tcgtgacaat aaattacgtc atatcatacg cctgcattcg atagttgaat
    10021 tattatcgac cgggttatcg ctgatgccgt tattaatata gctcttcgtt aaggttaaaa
    10081 atcaggcgac agtgcgttct ctgtgctgac taacataatg cagaggcgtc ataccgtaga
    10141 agtctttaaa gacagaaata aagtacgacg tactgttgta gccgcaggac tgtgatacct
    10201 gagagatatt tttaccgtcc atcattaatt catttacggc atagcgcatg cggcaggtgg
    10261 tgattatttg gctataactg gtgttttcgc ttttcagctt tttctttaac agacttgggc
    10321 taagacataa acaactggct accatactaa gattccagtc tttgtggata tcgctttcaa
    10381 taatttgata aacgctgtca cttacacaat tacgtaacat atacatcatt agtgaaagga
    10441 attttttact gtcgagaaaa cgggatagca cagtgaataa taatgcacgt gttcgttcct
    10501 tttctgactc agtttcagcg ggcatcatgc tatgttgcgc ggcaacgcga aagacgtctg
    10561 gcgtcaggca tggaagggtg aggatgggcg tagcgctacg ttgccatact ggtatttgcg
    10621 agagatcttt attcagaaac cggaggtaat ctttgatgat gtcgtgacta atatgagcaa
    10681 ccaaagtgtt attaagagag gagacgtcga taatattatt ttcacaattt aataacgcca
    10741 tatggttagc tttaaggcta ataggttctt tcccattcac ccttatccag acatcttttt
    10801 cagtcaataa aacaatacaa ggttggtcgc tgcaaatcct catacatgta ctcctgagtg
    10861 cgaataaaag accagttctc gctaaagcga agcgataccg ggaaatggtt atataattgt
    10921 atgatgaata taaacatgca taaaaataac gagttttact aatattacaa atttttatag
    10981 taatttctca tgtacatatt tttttacagg ctaagaaaag gataaataac aggcaaaaaa
    11041 aagcgcgggg tgggaccgcg caaaaagcat gacatttttt gtttgcagca atttttatga
    11101 aaacgttgcc atacttaaaa ggcctcaagc caggcggcgt aatgttattt aacaattacg
    11161 ccttcagcgg aatagtggtt acgctttcac acacataacg tggtaaatac cgtcaataat
    11221 ttctgtccct tctgtttcgt gttcaaatcc agggaaatga tgatcccagg attgcagcga
    11281 gcgtaaataa cttacttgcg gactgttttt atcgccgaag ttttcaccag acagcagcat
    11341 cgggattcct ggcggatacg ggataactga gtttgccgcg atacgtcctg gcagattttc
    11401 aatggatacc agttcgacat tgttgtcgac aatcgcgttg tacgcttcac gcggggtgat
    11461 ttccgccacc ggtaggccgg aataggcttc attcaaccgt gcgccagggt tgttttcttt
    11521 cagccaggca aacatggtgt cacccagatc gtgaatcccc atgttcgcgt aagtgtcagg
    11581 atattgttca acaagttccg gcatcacctg cgccagcggt gtgttggcgt catagtggcg
    11641 tttgaaggag caaagggtgt taaccagagt tccccatttc ccacgggtca cgcccataga
    11701 gaacaggaac ataatctgga agtcagtggt acgggtaggc acaatgccgt ggcgaccaag
    11761 ccaggctgtg accagcgccg ccggaacacc ggtttcttcc agttcaccat cttcacccat
    11821 tcccggagca aggatgctga ctttaatcgg gtcgagcata ctccagttat ccggaatatc
    11881 tttgaagccg tgccagcttt cgcccggatg catgacccag cagtcctgaa cggtggtcag
    11941 cagtttggtt ggtgcgtcag caaagtcata ggttttgccg gtttgtgggt cggtgacgac
    12001 ttctttgttc cacggtttga agaaccagct accgtcagcg gtgaactctt tatatagccg
    12061 cgccatcgcc tgacggaaat caaccgcttc gtcgatcact tcctgggtca gtgacaggcc
    12121 gctgttgccg tccatcatcg acaccgccac gtcgttggat gcgcagatgg catacagcgg
    12181 ggaggtggtg gcatgcatca tgtaggcctg gttgaagcgg gagaagttaa tcgccccacg
    12241 accttcacgt acatgaatat aagaggcctg tgacagcgca ttcagcagtt tgtgggtgga
    12301 gtgggtggcg aaaacggtag gaccgttgtg atcgccaggt tcgccgcgca tggcatagtg
    12361 atcggcatag atcgggttga aacgtgcata gccgtaccag gcttcgtcaa agtgcagacg
    12421 atcggaggtt ttttccagca gatcctgcgc ttctttagcg ttataacaca cgccgtcata
    12481 ggtacagttg gtcaccacgc agtaagacgg tttttgcccg gctttgtctt tagtcagcgg
    12541 gctttcattg attttcttct gcaaggtttc aggttgcatt tcctgcggat agattggccc
    12601 gataatgccg tagcggttgc ggcttggcac catgtagacc ggtttcgcac ctgtcagcat
    12661 caagccttgt tcgatggatt tatggcagtt acggtcaacg accacgacat cgttatcggt
    12721 catgcaagcc tgcatgatgg tgcggttaga gccggaagta ccgacgacta ccgaccagga
    12781 gcgatcggca ccaaatacgc gtgcggcata tttttcgctt tcgccaaatg cgccagtatg
    12841 gtcaagcaaa gaaccgaggg aagtgcgttc gatgcccatg tcggtgcgga acagattttc
    12901 accatagtag tcatggtaga aacgtccggc gggtgttttg gtaaaaccaa cgccgccctg
    12961 gtggcctggc gctgcccagg aatattcatg gatgtcgcta tatttcatca gcgcgctgaa
    13021 cagtggcggc aatagctgct ggcggtagcg ggtcatcgcg gcaacggcgc gtccggcgat
    13081 aaagtcggcg gtatcttcca gaatccaggc gaattcatcg acaagctcca gcaggtcgcg
    13141 atccattgcg gcgagggctt tttcccgatc gcccaacagg aagaccggca cgttttgttg
    13201 gcgctcatga agcttaccga tcaattgtct gacgttttga tgttcgtccg gatgttccat
    13261 ttgatagctg aacatcaggc agtcaatggc ttcgtttgaa gagagaatgg caaaaccatc
    13321 atcaaaggag gtggatttaa tcacggtaac attttgctgg cttaaagcat ctgccagacg
    13381 ctcaacggcg ttaccgaccc aggtgtcttg atggagaaac tcgctttcaa caattaatac
    13441 tttcatcatt gctta
//
LOCUS       DAPOXO010000117        12791 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPOXO010000117 DAPOXO010000000
VERSION     DAPOXO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12791
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.117"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            143..1273
                     /gene="fruB"
                     /locus_tag="ROH59_004425"
     CDS             143..1273
                     /gene="fruB"
                     /locus_tag="ROH59_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HDX4806829.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            1273..2211
                     /gene="fruK"
                     /locus_tag="ROH59_004426"
     CDS             1273..2211
                     /gene="fruK"
                     /locus_tag="ROH59_004426"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDX4806830.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            2228..3919
                     /gene="fruA"
                     /locus_tag="ROH59_004427"
     CDS             2228..3919
                     /gene="fruA"
                     /locus_tag="ROH59_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HDX4806831.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDFIPNDSALNGKNVWLGDISRAVAHPELFLSEAKGHAKPYTAPVAATAPVAASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATTE
                     GKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILDGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPETQIVEKNA"
     gene            4375..5316
                     /locus_tag="ROH59_004428"
     CDS             4375..5316
                     /locus_tag="ROH59_004428"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HDX4806832.1"
                     /translation="MREKDYIVIIGSANIDVAGYSHHPLNYVDSNPGKIKFTPGGVGR
                     NIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMSISDCISAEFLAQHQEFIRGAKVIVADCNLSEEALVWVLENSGETP
                     VFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFIDSV
                     RFAQGCSSMALACEYTNNPELSIANVTSLVENTECLN"
     gene            5304..6242
                     /gene="psuG"
                     /locus_tag="ROH59_004429"
     CDS             5304..6242
                     /gene="psuG"
                     /locus_tag="ROH59_004429"
                     /EC_number="4.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HDX4806833.1"
                     /translation="MSELTLSPELLQISAEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSAREIARA
                     MAVKWQTGLNGGLVVANPIPEQFAMPEETINAAIDQAVAEAEEQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLVG"
     gene            6336..7586
                     /locus_tag="ROH59_004430"
     CDS             6336..7586
                     /locus_tag="ROH59_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDX4806834.1"
                     /translation="MDIMRSVVGMVVLLAIAFVLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSIIEAAANGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFANVSLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTSGTLDVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(7653..8351)
                     /gene="yeiL"
                     /locus_tag="ROH59_004431"
     CDS             complement(7653..8351)
                     /gene="yeiL"
                     /locus_tag="ROH59_004431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HDX4806835.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            8481..9422
                     /gene="rihB"
                     /locus_tag="ROH59_004432"
     CDS             8481..9422
                     /gene="rihB"
                     /locus_tag="ROH59_004432"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HDX4806836.1"
                     /translation="MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAENT
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            complement(9690..10778)
                     /locus_tag="ROH59_004433"
     CDS             complement(9690..10778)
                     /locus_tag="ROH59_004433"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX4806837.1"
                     /translation="MNDREKQILKILRRNPLIQQNEIADILQISRSRVAAHIMDLMRK
                     GLIKGKGYILTEQDYCVVVGAINMDIRGMADIRYPQAASHPGSVHCSAGGVGRNIAHN
                     LALLGRDVHLISAIGNDFYGETLLEETRRAGVNVSNCIRLHGHSTATYLAIANKQEET
                     ILAINDTHILQQLTPQLLNTSRDLIRHAGVVLADCNLTPEALEWVFTIADEIPMFVDT
                     VSEFKANKVKNWYSRIHTLKPTQNELEILWGQPIKDDNDRIRAVNSLHQQGVKRIFVY
                     LKDESVFCSDKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGYSFRDSARFAIA
                     CAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(10782..11639)
                     /gene="nfo"
                     /locus_tag="ROH59_004434"
     CDS             complement(10782..11639)
                     /gene="nfo"
                     /locus_tag="ROH59_004434"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDX4806838.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            complement(11713..12762)
                     /locus_tag="ROH59_004435"
     CDS             complement(11713..12762)
                     /locus_tag="ROH59_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HDX4806839.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGTNSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
BASE COUNT         3133 a         3014 c         3411 g         3233 t
ORIGIN      
        1 acggctttcc ttgcgcgctg aaacagaagt attatgcttc cttgaaacgt ttcagcgcga
       61 tcttgtcttt aaccctaagc caggttggcg ctttttttct catagaagct gaatcgtttc
      121 aattcagcaa gagaggagaa ctatgttcca gttatctgta caggacatcc atccgggcga
      181 aaaggccgga gacaaagaag aggcgattcg ccaggtcgct gcggcgctgg tgcaggccgg
      241 taatgtagct gaaggctacg tcaatggcat gctggcgcgc gaacagcaaa cctcaacgtt
      301 cctcggcaat ggtattgcta ttccacacgg cactaccgac acccgcgatc aggtgctgaa
      361 aaccggcgtt caggtatttc agttcccgga aggcgtcacc tggggggacg gccaggtagc
      421 gtacgtggcg atcggtattg ctgccagctc ggatgaacat ctgggcctgc tacgccagct
      481 gacccacgta ctgagcgatg attccgttgc tgaacaactg aagtcagcaa caacagcaga
      541 agaacttcgc gcattgctga tgggcgaaaa gcagagtgag cagctgaagc tcgacaacga
      601 aatgctgacg ctggatatcg tcgccagcga tctgctgact cttcaggcgc tgaacgctgc
      661 gcgtctgaaa gaagcggggg cagttgacgc cactttcgtc accaaagcca tcaatgaaca
      721 accgctgaac ctcggacagg gtatctggct gagcgatagc gccgaaggca atctgcgtag
      781 cgcgattgcg gtaagccgtg cggcaaatgc ttttgatgtg gacggcgaaa cggcagccat
      841 gctggtgagt gtggcaatga atgacgatca gcccatcgcg gttcttaagc gtctcgctga
      901 tttgttgctc gataataaag ctgaccgctt gctgaaagcg gatgcggcaa cgttgctggc
      961 gctgctgacc agcgatgatg cgccgaccga cgacgtgtta agcgcggagt ttgtggtgcg
     1021 caatgaacac ggcctgcatg ctcgtccagg taccatgctg gtcaatacca ttaaacaatt
     1081 taacagtgat attaccgtga caaaccttga tggcaccggc aaaccggcaa acggacgtag
     1141 tctgatgaaa gttgtggcac ttggcgttaa gaaaggtcat cgcctacgct ttaccgccca
     1201 gggtgcagat gctgaacagg cgctgaaagc cattggcgac gctatcgctg ctggtcttgg
     1261 ggagggcgca taatgagcag acgtgttgct acgatcaccc ttaatccggc ttatgacctt
     1321 gttggtttct gcccggaaat tgaacgcggc gaagtgaacc tggtgaaaac caccggtctg
     1381 catgcggcgg gtaaaggcat caacgtggcc aaagtattaa aagacctggg aattgatgtc
     1441 accgttggcg gcttcctggg taaagacaat caggatggtt ttcagcaact gttcagcgag
     1501 ctgggcattg ccaaccgttt ccaggttgta caggggcgca cccgaattaa cgttaagctg
     1561 acggaaaaag acggcgaagt gaccgacttc aacttctcgg gttttgaagt tacccccgcc
     1621 gactgggaac gctttgtgac tgattctctg agctggctcg gtcagttcga tatggtctgt
     1681 gtcagcggaa gcttaccgtc aggcgtcagc ccggaagcgt tcaccgactg gatgactcgc
     1741 ctgcgtagtc agtgtccttg cattatcttt gatagtagcc gtgaagcgtt agtagcaggt
     1801 ttgaaagcgg caccgtggct ggtgaaacct aaccgccgcg agctggaaat ctgggcaggc
     1861 cgtaaactgc ctgaaatgaa agatgtgatt gaagctgcac atgcgctacg tgaacaaggt
     1921 attgcgcatg ttgttatttc actgggtgcc gaaggcgcgc tttgggttaa tgcctccggc
     1981 gaatggatcg ccaaaccacc gtcagtcgat gtcgtaagca ccgttggcgc aggggattct
     2041 atggttggtg gcctgattta tggcttgctg atgcgtgaat ccagtgaaca cacactgcgt
     2101 ctggcgacag ctgttgcagc cctggcggta agtcaaagca atgtgggtat taccgatcgt
     2161 ccgcagttgg ccgcaatgat ggcgcgcgtc gacttacaac cttttaactg acagcaggag
     2221 aggcataatg aaaacgctgc tgattattga cgctaatctc ggtcaggcac gcgcctatat
     2281 ggcgaagacc ctgctgggcg cggcggcgcg aaaagcaaaa ctggaaatca tcgacaatcc
     2341 gaacgacgca gaaatggcga ttgttctcgg tgatttcatc ccgaatgaca gcgcgctgaa
     2401 cggtaaaaat gtctggctgg gcgatatttc ccgggcagtt gcgcaccctg agctgttcct
     2461 gagtgaagcc aaaggccatg cgaaacctta cactgcgccg gtcgctgcga cagcaccggt
     2521 tgctgctagc ggtccgaaac gcgtagttgc ggtgactgct tgcccgactg gtgtagcaca
     2581 cacctttatg gcggctgaag ccattgaaac cgaagcgaaa aaacgtggct ggtgggtgaa
     2641 agttgaaacc cgtggttctg ttggcgcggg taatgcaatc acacctgaag aagtcgcagc
     2701 agcggatctg gtgattgtgg cggcagatat cgaagtggat ctggcgaaat ttgctggtaa
     2761 accgatgtat cgcacctcta ccggtctggc gctgaagaaa actgcgcagg aactggataa
     2821 agcggttgct gaagcaacgc cgtatgaacc agcgggcaaa gctcaaacag cgaccactga
     2881 aggtaagaaa gagagtgcag gcgcttaccg tcacttgctg acgggcgtct cttacatgct
     2941 gccgatggtt gttgcaggtg gtctgtgtat cgcgctttct tttgcttttg gtatcgaagc
     3001 gtttaaagag ccgggtacgt tggcagcggc gctgatgcag attggtggtg gttcagcctt
     3061 tgcgctgatg gtgccggtac tggcaggtta tattgccttc tccattgccg atcgtccggg
     3121 tctcacgccg ggtctgattg gcggtatgct ggcggttagc accggttctg gcttcattgg
     3181 cggtattatt gcgggcttcc tggcgggtta cattgcgaag ttaatcagta cgcaactgaa
     3241 actgccacag agtatggagg cactgaaacc gatcctgatc attccgctaa tttccagtct
     3301 ggtggtcggt ctggcgatga tctacctaat cggtaaaccg gttgctggca ttctcgatgg
     3361 gttgactcac tggctgcaga ccatggggac tgcgaatgcg gttctgctgg gggcgatcct
     3421 cggtggcatg atgtgtactg acatgggcgg tccggtaaac aaagcagcgt acgcattcgg
     3481 tgtgggtctg ctgagtactc aaacctatgg cccgatggcg gcgattatgg cggcaggtat
     3541 ggtgccaccg ctggcaatgg gtctggcaac aatggtggcg cgtcgtaaat tcgataaagc
     3601 gcagcaggaa ggtggcaaag ccgctctggt acttggtctg tgctttattt cggaaggtgc
     3661 aattccgttt gctgctcgtg atccgatgcg tgtgctaccg tgctgtatcg ttggtggggc
     3721 gctgactggc gcaatctcaa tggcgattgg tgcgaaactg atggctccgc acggtggtct
     3781 gtttgttctg ctgatccctg gcgctattac gccggtattg ggttacctgg tagcaattat
     3841 tgccggtacg ctggtggcgg gtttggccta tgccttcctc aaacgcccgg aaacacaaat
     3901 agtagaaaaa aacgcataat ttctcttcat catcggggat gagacatctc tgccccgatg
     3961 atgacaaacg caaaattgcc tgatgcgcta tgcttatcag acctacatga accctgcaat
     4021 atattgaatt tttgcgcttt tgtaggtcgg ataaggcgtt tacgccacat ccagcatgaa
     4081 caaagcgcgc attgtcaaca atctgagggc agaaacatct ctgccctttt tcttgcctgc
     4141 catattgtgt gttacacatc acaactttct cttttgttgc tgcataaata gacaaatttt
     4201 gtgaccgcct tcatatctgg ccgatttcgt tttttctgat cgatttacat tacgttaaac
     4261 atgcttatta tgaacatgtg tttaaatctg aacacatgct ctaatagtct tattgactgt
     4321 aatgactatt ttacccaatt tcttcgttgg caatttattg ccagggggcg tgctatgcgc
     4381 gaaaaggact acatagtaat tattggctcg gcgaatattg atgtggctgg gtattcacat
     4441 catccattga attatgtgga ttcgaatccc ggaaaaatta aatttacccc aggtggcgtg
     4501 ggaaggaata tcgctcataa tctggcgtta ctggggaaaa atgcctggct tttaagtgca
     4561 gtaggtggtg atttttatgg gcaatcatta ctggcgcaaa ctaatcaatc cggtgtttat
     4621 gtcgataaat gcttaattgt tccgggtgag aatacatcca gctatttatc actgctcgat
     4681 aatacaggag aaatgcttgt cgcgataaat gatatgagta ttagtgactg tatttctgca
     4741 gaatttcttg cccagcatca ggagtttatt cgcggtgcaa aggttattgt cgcggattgc
     4801 aaccttagtg aagaggcgct ggtctgggtt ctggaaaata gcggggaaac gcctgtattt
     4861 attgatccgg tatcggcatg gaaatgcgtc aaaatccgcg atcatctgag caaaatccat
     4921 acgttaaaac ctaaccgtct tgaagccgaa acgttgagcg gaattgcact ttccggacgt
     4981 gaagatgtcg caaaggtcgc cgcctggttt catcaacacg gcctgaaccg cctggtgctg
     5041 agcatgggag gggatggcgt ttactacagt gatatcaacg gtgaaagtgg gtggtcggcc
     5101 cctattaaaa cgaatgtcat caatgttact ggggcaggcg acgccatgat ggcggggctg
     5161 gcctcctgtt gggtagacgg tatgccgttt atcgattctg ttcgatttgc gcagggatgt
     5221 tcgtcaatgg cacttgcctg tgaatatacc aacaaccctg aattatcaat tgccaatgtt
     5281 acatcgttag tggagaacac agaatgtctg aattaactct gtcccctgaa ttattacaaa
     5341 tatccgctga agtacaggat gctttaaaaa ataaaaaacc ggttgttgcg ctggaatcga
     5401 ccataatttc tcacggaatg ccattcccac aaaatgccca aaccgcaatt gaagtagaag
     5461 aaacaattcg taaacagggc gcagtaccag ccactatcgc cattattggc ggtgtgatga
     5521 aagtgggctt aagtaaagaa gaaatcgaat tgctgggccg tgaaggacat aacgtgacga
     5581 aagttagtcg tcgtgattta ccttttgtcg ttgctgcagg gaaaaatggc gcgactaccg
     5641 ttgcatcaac catgattatt gcagcactgg ctgggattaa agtttttgca accggaggta
     5701 ttggtggtgt gcatcgcgga gcggaacata ccttcgatat ttctgccgat ttacaggaac
     5761 tggcaaatac caatgtcact gttgtttgtg cgggggcaaa atctattctc gatttaggat
     5821 taacaacaga atatttagaa accttcggtg taccgttaat tggttatcag acaaaagcgc
     5881 tgcctgcgtt tttctgccga accagcccat ttgatgtcag cattcgtctc gacagtgccc
     5941 gcgaaattgc tcgcgcgatg gcagtgaagt ggcaaaccgg tttgaacggc ggcctggtgg
     6001 tagcgaaccc gatcccggaa cagtttgcga tgccagaaga aaccatcaat gcagcaattg
     6061 atcaagccgt tgctgaagcc gaagaacagg gtgttattgg gaaagagagt acaccgttcc
     6121 tgctggcgcg tgttgcggag ctaaccggcg gtgatagcct gaaatccaat attcaactgg
     6181 tctttaataa cgccattctg gcgagcgaaa ttgccaaaga atatcagcgt ctcgtgggtt
     6241 aatttctggt gggcagaaag ccgtcgcccg tactcatcaa acataccaaa acctggcgct
     6301 gacgccgggt ttactggcat gaagggaaaa tcattatgga tataatgaga agtgttgtgg
     6361 ggatggtggt attgctggca attgcctttg tgttgtcggt aaataaaaag agcatcagct
     6421 tgcgcacggt tggggctgcg ctgctgctgc aaattgccat tggtggcatc atgctctatt
     6481 ttcccccggg aaaatgggca gtagagcagg cggcattagg cgtccataaa gtgatgtcct
     6541 acagtgacgc aggaagtgcc tttatttttg gttcgctggt cggtcccaaa atggatgttc
     6601 tgtttgacgg tgcgggcttt atcttcgcct ttcgcgtact cccggcgatt attttcgtta
     6661 ccgcgcttat cagcttgctg tactacattg gcgtaatggg gctgctgatt cgtattcttg
     6721 gcagtatttt tcagaaagcc ctcaacatca gcaaaatcga atcttttgtc gcagtcacca
     6781 ctatcttcct cgggcaaaat gagatcccgg cgatcgttaa accttttatt gatcgcatga
     6841 atcgcaacga gctatttacg gctatttgta gcggcatggc gtctattgcg ggttcgatga
     6901 tgattggcta tgccggaatg ggcgtgccga ttgactattt gttagccgct tcgctgatgg
     6961 ctattcctgg cggtatcctg tttgcacgta ttcttagtcc ggcgacggaa ccttcgcaag
     7021 ttacgtttga aaatctgtcg tttagcgaaa caccgccaaa aagcattatt gaagctgcgg
     7081 cgaacggtgc aatgaccggg ctgaaaatcg ccgccggtgt ggcgacggtg gtaatggcat
     7141 ttgtggcgat cattgcgctg atcaacggca ttattggtgg agttggcggc tggtttggtt
     7201 ttgccaatgt ctctctggaa agcattttcg gctatgtgct ggccccgttg gcatggatta
     7261 tgggggtgga ctggagtgat gcaaatcttg ccggaagttt gattgggcag aaattggcga
     7321 ttaatgagtt tgttgcttat ctcaatttct cgccctatct gcaaacgagc ggcacgctgg
     7381 atgtcaagac cattgccatt atctcgttcg ccctctgtgg gtttgctaac tttggttcta
     7441 tcggtgttgt cgttggagcg ttttcggcta tttcgccaaa acgcgcgccg gaaatcgccc
     7501 agcttggttt acgggcgctg gcggcggcga cgctttccaa cctgatgagc gcgaccattg
     7561 ccgggttctt tattggttta gcttgagttt cattgccgga tgtacgcctt attaagcgtt
     7621 gcatccggca atcgcactat tgccaataat ttttactgca tcatcccgga gaatttattc
     7681 tccgggtcca tctccagcgc cagtcctgac aactgctttc tgtttttaat gagataccct
     7741 ttcttgcttt taattaataa accgtcatta atgaattgcg cgagaacata taaaagatgt
     7801 cgataagaaa cgcctaaata ctctgccgct tgcgtatgct tttcgtgata aagatcacct
     7861 tcctgcgaga gtaatataaa agctgccagg cgattcacta acggaaatga ttgattctga
     7921 gttaaagaaa caatattacg ataattttta tgacttaagg tgacgcagag ttttcgtaaa
     7981 aatagcgtgt cgtttaataa cagcgggcgg taatgcttca tagggagcgc aaggcaccaa
     8041 cactcttcaa tagcctgcac tgcacgcggt tcatggtctt tgtcgattaa ctcaatctcg
     8101 ccaataaaac agggcgcggc aaagaaatcg atcagcgaca cgcgaccatt agcaagcgtg
     8161 acgtaaagcc tggcgcggcc tcgcgtcagg taaaacagcc aggacggctg ttgcccttcc
     8221 tgcacaatgt agtcacgcgc taaaaaatga aacagccgcg tatcggctga aacatccgtt
     8281 gaaaagcaat ccttaaacgc agattcactc atcaattgct gcttaagatc attattgtgg
     8341 atttctttca cgatgtttat ccgctatgag atttctcata tttagcatac gtacgctgtt
     8401 gttaagattc aatcatcggc caggtcgaat tttctttgct gtagaaacaa taacgcaact
     8461 ggaaacagag gaaataaaca atggaaaaga gaaaaattat tctggattgt gatccgggtc
     8521 atgatgatgc tattgctata atgatggcgg cgaaacatcc tgcgattgat ttattaggta
     8581 tcaccattgt agcgggtaat caaaccctcg ataaaacatt aattaatggc ctgaatgttt
     8641 gccagaaact ggagattaat gttccggttt atgcggggat gccgcagccc attatgcgtc
     8701 aacaaattgt tgccgataat attcacggtg aaaccggact ggatggcccg gtattcgagc
     8761 cgctgacccg ccaggcagaa aacactcatg cggtgaaata tatcatcgat acccttatgg
     8821 caagcgatgg cgatatcact ctggtgccgg ttggtccgtt gtcaaacatc gcggtggcaa
     8881 tgcgtatgca acccgcgatc ctgccgaaaa tccgtgaaat tgttctgatg ggcggcgctt
     8941 atggtactgg caacttcacc ccatctgctg agttcaatat ctttgctgac ccggaagccg
     9001 cacgcgtggt gttcacctcc ggcgttccat tagtgatgat gggcctcgat cttaccaacc
     9061 agaccgtttg caccccggac gtgattgctc ggatggaaag ggctggcggc cctgcgggag
     9121 agctgttcag cgacatcatg aacttcactc tcaaaacgca gttcgaaaac tacggcctgg
     9181 ctggcggccc ggtgcacgac gccacctgca tcggttattt gattaaccct gatggcatta
     9241 aaacccagga gatgtacgtc gaagtggacg ttaacagtgg cccttgctat gggcgtaccg
     9301 tctgcgacga gttgggcgtt cttggcaagc ccgccaatac caaagtcggc atcactattg
     9361 atacagactg gttctgggga ttagtcgaag agtgcgtacg cggctacatc aaaacccatt
     9421 aagtgttgat aacaagccgg gtcagtatcg caagatgcag gcccggctat ttatgatggg
     9481 cagagagccg tcgcccaaaa tgacatgaag agataataac tatggatgtc atgagaagtg
     9541 ttctgggaat ggtggtattg ctggctattg cgtttttgct gtcagtaacc tgatgagtgc
     9601 tactattgca ggattcttta ttggtttagc gtagtgcgca atttatgagc cggataagat
     9661 gcggtcaagc gtcgaatccg gcaacattgt tacaccattg gcactaatga aagcgcgtta
     9721 tcggcagaca gggtagggtt gtttaagctg ccgctggcac gcgaaattgc cgcgcaggct
     9781 atcgcaaaac gggcgctgtc gcggaaactg tatccttcaa gaaagctata taccaggccc
     9841 gccataaaac catcgtcagc accaaaactg tctactgtcg tatgcgctgg tgcggtcagc
     9901 aaaaattgtt ctccatcctt atcgctgcaa aatacagatt catctttcag ataaacaaaa
     9961 atgcgtttaa caccttgttg atgcagcgaa tttacagctc tgatgcgatc gttgtcgtct
    10021 ttaatcggtt gcccccacaa aatttccagt tcattttgtg ttggtttcag agtgtggatc
    10081 cggctgtacc agttttttac tttgttcgct ttaaattcgg aaacggtatc gacaaacatc
    10141 ggaatttcat cagcaatggt aaagacccac tccagggctt caggtgtgag attacaatca
    10201 gccagcacca caccagcatg gcgaatcaag tcccgtgaag tattgagcag ttgaggcgtt
    10261 agctgttgca gaatgtgtgt gtcattgatt gccaggatag tttcttcctg cttattagcg
    10321 atagcgagat aagttgcagt gctgtgtcca tgcagacgaa tgcagtttga aacgttcacg
    10381 cccgcgcggc gcgtttcttc cagtaatgtc tcgccgtaaa aatcgttgcc aatagctgaa
    10441 attaaatgca catcccgacc aagcagagcc aggttatgcg cgatattacg tccgacgccg
    10501 cctgcggaac agtgaacaga acctggatga gaggctgctt gcgggtaacg gatatccgcc
    10561 attccgcgaa tatccatatt gattgcaccc acaaccacac agtaatcctg ctcggtaagg
    10621 atatatcctt tgcctttaat caaacccttg cgcatcaaat ccataatatg agcggcaaca
    10681 cgtgagcggc tgatttgcag aatatcggcg atttcattct gttgaatcag cgggttacgc
    10741 cgtaaaattt taagaatctg tttttccctg tcgttcatcg atcaggccac cgctttttca
    10801 gtttgttgcg ctttcagcca ggcgatctct tctgcccaga tatccgggtt gatggtttca
    10861 aggatcagcg gaatgccgtc gaaacggtcg tcctgcatga tccagcggaa cgcatcatga
    10921 ccgatattgc cttcgccgag gctatgatga cggtcaacgc ggctgccaaa ggtgcttttc
    10981 gcatcgttga ggtgcatccc gcgcagatac ttaaagccta caatacgggc aaaatcagcg
    11041 aacgttttct cgcattcggc aggagtacgc aaatcatacc cggcagcgaa agcatggcag
    11101 gtatcaatgc agacgccgac gcgggattta tcttccacgc cgtcgataat cgccgcgaga
    11161 tgttcgaatt taaaccctaa gttactgccc tgaccggcgg tgttttcaat caccgcggtg
    11221 acaccttgag ttttatccag cgcaatgttg atggattcgg caatacgcgc aaggcaatcc
    11281 tcttctgaaa tctgcatcag atggctgcca gggtggaagt tgagcaaaga aagccccagc
    11341 tgttcgcaac gctgcatttc atctataaag gcatcgcgcg atttttccag agcttcagca
    11401 accggatgtc cgaggttaat cagataactg tcgtggggaa gaatttgcgc cgatgtgtag
    11461 tgatattttt cacaggcggc tttgaattca tcgatggttt gcgtcgtgag cggtgcggca
    11521 cgccactgac gttggttttt ggtgaacaag gcaaacgcgg ttgcgtcgat ttcggcggcg
    11581 cgaattgcgg catttgccag accgccagca gcactaacgt gcgctccaat gtatttcatg
    11641 cgaggactcc tgttaaaccc gctggaggaa aacggtaatg atagcgggtt aacaggagca
    11701 agatgtagtg gtttatgcga tgacgctttg aatcacatag ttaatcgcac caccaccaac
    11761 aatcagccag gcaaacagta ccagtgccat cagcagaggt ttcgccccgg cttttttcag
    11821 cgcgctgacg tgagtggtca gacccagcgc cgccatcgcc attgccagca ggaaggtatc
    11881 cagcgttacc agcatgttca ccacgctctg cggtaacagg tggaacgagt taaagatggc
    11941 aacgacgatg aacaagatgg caaaccacgg aatagtgatt ttgcttttct cgccgctgtt
    12001 cgtcccagac agctgtttaa cacgcgccgc cagcaggatg aggaacggag ccagcatcat
    12061 cacgcgcagc attttggaaa taactgctgc gttttctgca tccgggctga tggcatgacc
    12121 tgccgccacc acctgcgcca cttcgtgcac agtagaacca atgtagatac cgaaagtttc
    12181 cggactaaac cattgagaca tcagcggata tatcgccggg tagaggaaaa tcgcgacggt
    12241 cccgaagata acaacggttg caacagccac ggttacttta ctggcttctg ctttcactac
    12301 cggctcagtc gccagtaccg cggcagcacc acagatactg ctaccggcac cgatcaacca
    12361 gctggtgtgc ttatccagac caaacacttt ctgccccagg aagcaagcca gcaggaaggt
    12421 actggacagc gtcaacacgt caatgatgat cccactgata ccgacatcgg caatttgcga
    12481 gaacgtcaga cggaagccat aaagaatgat acccagacgt aataaatatt gcttggcaaa
    12541 cagcacacca ccgtcacagc ttttccagat gtgcgggtaa atggtgttgc ctaaaaccat
    12601 ccccaacaag attgcgaggg tgagggcact aaacccggca cccgcaaccg cgggaatgga
    12661 accaccccac agggcgaccc cggtgataac tgcactcagg gctaaccccg gaataaaatg
    12721 ccacagtgta cgatgttgtt tctgtaaggt gatattcgtc ataaccctct cctttaaccg
    12781 ggcataaggt t
//
LOCUS       DAPOXO010000118        12747 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.118, whole genome shotgun sequence.
ACCESSION   DAPOXO010000118 DAPOXO010000000
VERSION     DAPOXO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12747
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.118"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(37..534)
                     /locus_tag="ROH59_004436"
     CDS             complement(37..534)
                     /locus_tag="ROH59_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000334561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDX4806840.1"
                     /translation="MCGRFAQSQTREDYLAFLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSHMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQAVFIAAIGSTPFERGDEAGRSFCKPAQGLSVTVAMA
                     VRANL"
     gene            complement(643..876)
                     /gene="yedF"
                     /locus_tag="ROH59_004437"
     CDS             complement(643..876)
                     /gene="yedF"
                     /locus_tag="ROH59_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDX4806841.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            complement(873..2078)
                     /gene="yedE"
                     /locus_tag="ROH59_004438"
     CDS             complement(873..2078)
                     /gene="yedE"
                     /locus_tag="ROH59_004438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HDX4806842.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            2265..2678
                     /locus_tag="ROH59_004439"
     CDS             2265..2678
                     /locus_tag="ROH59_004439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX4806843.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLTGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            complement(2712..4199)
                     /gene="amyA"
                     /locus_tag="ROH59_004440"
     CDS             complement(2712..4199)
                     /gene="amyA"
                     /locus_tag="ROH59_004440"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDX4806844.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTIHLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(4277..4642)
                     /gene="fliT"
                     /locus_tag="ROH59_004441"
     CDS             complement(4277..4642)
                     /gene="fliT"
                     /locus_tag="ROH59_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HDX4806845.1"
                     /translation="MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKIKQLLQIRMDELAKLVGQSSVQKSV
                     LSAYGDQGGFVLAPQDNLF"
     gene            complement(4642..5052)
                     /gene="fliS"
                     /locus_tag="ROH59_004442"
     CDS             complement(4642..5052)
                     /gene="fliS"
                     /locus_tag="ROH59_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDX4806846.1"
                     /translation="MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV"
     gene            complement(5068..6483)
                     /gene="fliD"
                     /locus_tag="ROH59_004443"
     CDS             complement(5068..6483)
                     /gene="fliD"
                     /locus_tag="ROH59_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDX4806847.1"
                     /translation="MASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKL
                     SAYGTLKSALESFQTANTALNKADLFTATSTTSSSSAFSATTTGSAIAGKYTISVSQL
                     AQAQTLTTKNSQKDSKAAIATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNA
                     KAGVSASIINVGNGEYRLSITANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGM
                     IESVTAQNAKLTVNNVEIENSSNTISDSLEDITLNLNDVTTGNQTLTISKDTSKAENA
                     VKAWVDAYNTLQDTFSSLTKYTAVDAGAESQDSSNGALLGDSTLRTIQTQLKTLLANT
                     HSSSNYKTLAQIGITSDASTGKLEIATDKLQTALKNDAAGIGEMFIGDGKSTGVTTGI
                     SSNLTSWLSSTGIIQAAKDGVSKTLNNLTDQYNAASERIDTLMTRYKAQFTQLDVLMN
                     SLNSTSSYLTQQFDTSNSNSK"
     gene            6731..7780
                     /locus_tag="ROH59_004444"
     CDS             6731..7780
                     /locus_tag="ROH59_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079755.1"
                     /note="structural flagella protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin FliC"
                     /protein_id="HDX4806848.1"
                     /translation="MAQVINTNSLSLITQNNINKNQSALSTSIERLSSGLRINSAKDD
                     AAGQAIANRFTSNIKGLTQAARNANDGISLAQTAEGALSEINNNLQRIRELTVQASTG
                     TNSDSDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKNDSMKIQIGANDNQTISIGL
                     QQIDSTTLNLKGFTVSGMADFSAAKLTAADGTAIAAADVKDAGGKQVNLLSYTDTASN
                     STKYAVVDSATGKYMEATVVITGTAAAVTVGAAEVAGAATADPLKALDAAIAKVDKFR
                     SSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLS
                     KANQVPQQVLSLLQG"
     gene            7944..8663
                     /gene="fliA"
                     /locus_tag="ROH59_004445"
     CDS             7944..8663
                     /gene="fliA"
                     /locus_tag="ROH59_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HDX4806849.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDNNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            8709..9260
                     /gene="fliZ"
                     /locus_tag="ROH59_004446"
     CDS             8709..9260
                     /gene="fliZ"
                     /locus_tag="ROH59_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HDX4806850.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIV
                     NKIEISRLDTLLDENGWQVEQQSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGTVREYVVRLRRLGNHLHEQNISLDQLQDGFLDEILAPWLPSTSTNNYRIALRKYQ
                     HYQRQTCTGLVQKSSSLPASDIY"
     gene            9348..10148
                     /gene="tcyJ"
                     /locus_tag="ROH59_004447"
     CDS             9348..10148
                     /gene="tcyJ"
                     /locus_tag="ROH59_004447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4806851.1"
                     /translation="MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTADDLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
     gene            10253..11239
                     /gene="dcyD"
                     /locus_tag="ROH59_004448"
     CDS             10253..11239
                     /gene="dcyD"
                     /locus_tag="ROH59_004448"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HDX4806852.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEVAVNISSVVVASGSAGTHAGLAVGLEQLMPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            11254..11922
                     /gene="tcyL"
                     /locus_tag="ROH59_004449"
     CDS             11254..11922
                     /gene="tcyL"
                     /locus_tag="ROH59_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HDX4806853.1"
                     /translation="MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            11919..12671
                     /gene="yecC"
                     /locus_tag="ROH59_004450"
     CDS             11919..12671
                     /gene="yecC"
                     /locus_tag="ROH59_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HDX4806854.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGVAKALFADPQQPRTRQFLEKFLLQ"
BASE COUNT         3134 a         3198 c         3312 g         3103 t
ORIGIN      
        1 tggttgagtg gaaaaatgcc actgaaacgc aatggcttaa agattcgccc tcacagccat
       61 tgcaacagtc actgaaagac cctgagcggg cttacaaaaa cttcttccgg cttcgtcacc
      121 acgctcaaac ggtgtgctac ctatcgcggc tataaaaaca gcttgtccat cagcacgata
      181 gataaaataa ggctgctttt tgtcgccttc ttttttccac tcaaaccagc catcggcaaa
      241 acagattgcc cgaccatgtt gccagagcgg tttaaacatg tgactggttg cggcagtttc
      301 tacgcgggcg ttaatcagcg gcggtttatc ccaccatccg ggagcatatc cccagaaaac
      361 cggatccaga tgaaggtgtt catcacgttc actgagcaga aggactttgg ttcccggcgc
      421 gacgttgtat ctgccaatag gttcgggatc gtagggaata tcgcgttcaa tatcttccgc
      481 gagaaacgcg aggtaatctt cacgcgtttg ggattgggca aagcgtccac acatagaaac
      541 ctcctgagag cacactgaaa agaataggag agagggcggg taaaatctat gtgatagaga
      601 ggtaacgatg ttcccgctgt gggccacagc gggaatgagg gattacttct gaattaaata
      661 acgaatggtc ggcccgtctt gctgaatatc cagcaccgta tagccgtgat tacgcgcatc
      721 cagtggaata ttattgatcg actgcggaca gtcgctcacc acttccagga tctccccttt
      781 ttttaactgc ggcatcgcct caagggttgc gactgccgga taagggcagg gttcacccac
      841 catatcaaga cggtaatcag gaacgatatt tttcatgcga tctccttagc agtctgcggt
      901 gccgcacggc ggaagaagcg tttttcccag ccaataatca acattagagc agcaaacaac
      961 agcaaatatg tcaccagcag gccgcccatc gggccaaagg ttttcagcag gttgattttg
     1021 tcccagtcgg tggccagcgc cggagcgaaa tcatcccagt agtacgccag aatcgttgag
     1081 ccgatcacgt tgcccagacc gacccaccag tagtgcacct ggccttctac cgcgcggtac
     1141 atccagccgg tttcgcagcc gcctgccagc acgatgccaa aaccaaacag taaaccacca
     1201 attaccgcgt ttggtcccgc ccacatgatt ttgggttcaa cgcctaactg tacgtaactg
     1261 aagatcccga tggcacttac cgccataccg ataatgattg ctttcgccat atgggtacgt
     1321 ccggtgatcc acatatcgcg gaacgccgaa gtaaagcaga tttgcgcacg ttcaatcagt
     1381 aaaccaaagc cgacgccaaa cagcattgcc agccccagtt tgggctggtt catcgccgtc
     1441 agcagcgccc agcccagcat gccgaaaaag accagcatcc cgagacgaaa acgacgccgc
     1501 gcctgatccg gtttttgcgt caacggtgag gcagcagaaa ctttctgcat tttcacggga
     1561 atacggaaga tgggcagaag ggtaaagcgc gcgccaaacc atgaaccaat ggcagtggcg
     1621 atggcaaaga accaggcgtg cagcgagaac tgtggaattc cggtaaagaa cgccgccagg
     1681 ttacagccca ttgccagacg tgcgccaaaa ccggcgataa taccgccaat gatggcctgc
     1741 ataatgcgga tacggctgcg cggcatgcgc agtttgacat tgttggccca cagcgctgcg
     1801 gcaaaacagc cgccaaacat accgaggatc atcattccgt cgatgcgggt taatggcgat
     1861 ccttccagat ggataatttt aaaataaccc cactcttcag catggacgcc gaacaactgc
     1921 aggagctgac cgccccaacg ggtaaattca cccgtgactg cccaaaaggt gccagtgatg
     1981 ccaaaatagt aagtggagag aatacccgcc gcgatgaccg cggggatggg cgcccagaat
     2041 ttaatcaacc aggcgtgttt gaattgctgc catgacatga atgtagcctc tgaactcaga
     2101 aggtttgaaa caagagtcgc gaatcataca ccatgcaaat ttattttcgg ggtaataatt
     2161 cacaaaaata atggttagat caaatttctc tctgaacctg gaaaggctgg cgacatcagg
     2221 gctttaatgc cacaatcctc ttttcttctc atgcaggacg aatgatgaaa aaactcgcaa
     2281 ttgcaggtgc gctcatgttg ctggcgggct gtgccgaagt cgaaaactat aacaatgtcg
     2341 tgaaaacccc cgcgccggac tggctgacgg gttactggca gaccaaaggg ccgcaacgtg
     2401 cgttggtcag tccggaagcg ataggcagcc tcattgtcac taaagagggc gataccctgg
     2461 attgccgtca gtggcagcgg gtgattgccg tgccgggtaa gttgacattg atgtctgatg
     2521 atctcactaa cgttaccgta aaacgtgagc tgtacgaggt tgagcgtgac ggtaacacca
     2581 ttgagtacga tggtatgacg atggagcgtg tggatcgccc gacggcagag tgtgccgccg
     2641 cgctggataa agcgccgtta ccgacgccac tgccgtaatg aaatctcccc ggcttgccgc
     2701 cggggatgga tttaaatcac ctcttcgata acccacacgc tgacgctgcc gccgttgcaa
     2761 aagaaggtcg cttcgccgtt ttcgtctgtc actacgctct cttgccggtt ccccagaaaa
     2821 tcgcgccagg ttttattgcc gtaattctct cccagatgaa tggttttttc gccatcatct
     2881 ccgttcgaca tgaccaccac gcagccggga tattcgtcgg tgccactgcg gctaaaggca
     2941 atgcagttcg gatggtcgaa aaataacgtc tgtacaccgt gggcgaaacg ctgacgggcg
     3001 agaattaact catcaagctg ttcgattatt ggcatatcta tcggataggt ttgcccgtca
     3061 ccaccgacat cttcgtaatg tgcaccgtag aggtccggat agaacaccga aggaacgcca
     3121 ttttcccgca acaaaattaa ggcatacgcc agcggtttaa accacggttc gacgggggct
     3181 tcgagggctt gcaacggttg ggtgtcgtgg ttggcaacga gggttacggc gtgaaaagga
     3241 tcggcttcca ccagcgtccc agtgaagatc tgcgtcatgt cgtagtcgcg acccatgcgc
     3301 gatgcttcat ggaatttcat ctgcagcggc gcatcaaaca gcatggtttt gccttccacc
     3361 tgatcaatat acgtttgcag tttatcgact tcatgcgacc agtattcagc cacaataaac
     3421 aacggctttg gcgcaacttc ctgtacgtgt tcgatccact ctttataaaa ccatgccgga
     3481 atatgtttga ccgcatcaag acgaaagccg tcgcattgcg tttgttccat cacccagcgc
     3541 gcccagtatt taatctcttc cgtcacggca tgattgcgaa aatcgatatt ctcccccatc
     3601 agataatcga aattaccgag ttcatcatca acctgatcgt tccagccttc tccggtatag
     3661 tcgttaacaa ttttaaaaat gccatcttca tcagggtttt cgatatggtc gataccgcta
     3721 aaacatttga aatcccagat aaactgcgag tattgcccgg cacgagcggg gaaggtgtaa
     3781 cgcgtccagc cttcacactc aatgatttct tcgtcaattt gcgtacggtc atcagcattt
     3841 acacgctgca cgcgaatagc ttctttttca tccgcgccca ttttgtggtt gactaccacg
     3901 tccagcagca ccgcaatgtc attacgtttc agggcgtcaa tggcggccag cagttgtgct
     3961 ttatcaccat atttagtagg gatgctgcct ttctgatcaa actcacctag atcaaataaa
     4021 tcataggagt cgtagccgac cgaatagccg cccgatgcgc ctttataggc gggcggcaac
     4081 cagaccatat tgataccaat atcattaaaa ccgtctgcgc gctcggccag ttcaggccag
     4141 agcttaccgc cttccgggta ataccagtga aaacattgta acagcgtggg attacgcatt
     4201 cttcgactcc attcaagggg aatattagaa gcgtagccgt aatcggatta ttcgcgagcc
     4261 atcggctcat taagattcaa aagaggttat cctgcggagc cagcacaaag ccgccctgat
     4321 cgccataggc acttaacacc gatttttgca ccgatgactg accgaccagt ttcgccagtt
     4381 catccatccg aatctgtaat aactgcttta tcttgctttc gttgtcgaga atcaggcgca
     4441 gcatcgggcg gagctgctcc tgcatcgtag tggacggggc aacctcttca gtcaggtgtg
     4501 cgatctcctg caccgcattc acatacgcca tttcgctggc gatgagttcg tcccattgtt
     4561 cttccgttgc caggcgtaac atgagctggc ttttttcgac gagttgttgc caggcgaaat
     4621 acaaatgcgg tgcattgttc atcagactgg gtcctgaatc aaagaagggg agagtaaaga
     4681 ctctttccag gcatcggcaa tattgcgcat taatgcttcc acttcttcga ctgcggagac
     4741 atcgttgcgt aaattggctt gcagcaaacg cctgaccata tagctataaa gagcaatcaa
     4801 gttttgggtt agttcgtctt tgctctcttc atcaagactc acccgcagtc cgttctcaat
     4861 gatgttgatc gcttttgaca aagagacgcc tttgccttgc tgattgttgt cctgcataaa
     4921 caggcgcgct ctaaccagtg cgctcaacac tccatcaaat agcatggtga ccaactgctg
     4981 ttggctggcg ctcattacgg cgctttcgac gccaatttgt gcataggcct gggtgccttt
     5041 tgccgcgtac atagtctctc ctgaagatta tttcgagttg ctatttgagg tgtcgaactg
     5101 ctgtgtcaga tagctactag tggagttcag cgagttcatt aacacatcta attgggtgaa
     5161 ctgggcttta tagcgcgtca ttaaggtatc gatacgttca ctggctgcgt tgtactggtc
     5221 ggtcaaatta ttcagcgttt tgctgacgcc atcttttgct gcctggatta tcccggtgga
     5281 agagagccaa ctggtcaggt tgctactaat gccggtggtt accccagtac ttttgccgtc
     5341 acctataaac atttcaccga taccagcggc atcatttttt agcgccgttt gcagtttgtc
     5401 ggtcgcgatt tccagcttgc cggtactggc atcgctggta atgccaatct gtgccagcgt
     5461 tttatagttt gaactgctgt gagtattggc gagcaaggtt ttaagctgag tctggatggt
     5521 acgcagtgtg gagtcaccga gtaatgcgcc attactggag tcctgacttt cagctccggc
     5581 atcgacagcg gtgtatttgg ttaagctgct gaatgtatcc tgcaatgtgt tataggcatc
     5641 cacccacgct ttaaccgcat tttcagcttt ggatgtgtct ttactgatgg tcagtgtctg
     5701 attaccggtg gtgacgtcat tcaggttgag ggtgatatct tccagtgagt cgctgatagt
     5761 gttactgctg ttttcaatct caacgttatt gactgtcagt ttggcgtttt gcgcggtgac
     5821 gctttcaatc atgccattgc tgctatcacc cggcgttccg ttgtaaccca taaaactttc
     5881 cagggcgctg tcgccgctga cgctaagttt catagcgtta ttgctgcccg tatcgttagc
     5941 ggtgatggac agacgatatt cgccgtttcc cacattgatg atactggcgc tgacaccagc
     6001 tttggcgttg ttaatggcat cgcgaatgcc ggaaagtgac gagttacccg cgctgatatc
     6061 aatcgtgacc ggatctttac cgccgccttg ttggatggtc agtacgctat cgctggtggc
     6121 gatggcggct ttactgtctt tttgactatt ttttgttgtc agcgtctgtg cctgcgccag
     6181 ttggctaacg ctaatggtgt atttcccagc aatcgcgctg cccgtggtgg tggcgctgaa
     6241 agccgatgaa ctgctggtgg ttgaggtggc ggtaaataaa tcggctttat tcagtgctgt
     6301 gttggctgtc tggaaactct ctagtgcact tttcagcgtc ccgtaggcgc tcagtttcgc
     6361 ggtgtaagag ctttgctgtt ttgatatcgg cgtcagggta gatttttctg ccgcctccag
     6421 actgtcaagg atgctgctta agtccagccc cgacccaacc ccaagcgttg aaatactagc
     6481 catatagttt ccttaatcat gcgacgtgta tagaacgaat accggggtta tcggcgtaag
     6541 cggggtaaag tttacgattt attttttgcc ttaatggcac gaacagcaac gaggaagggg
     6601 agtatttcga ccgctagaaa aaaattctaa aggttgtgag tgaccagacg ataacagggt
     6661 tgacggcgac gaagccgaag ggtggaagcc caatacttaa accgtagact tgaaaacagg
     6721 aaaatgaatt atggcacaag tcattaatac caacagcctc tcgctgatca ctcagaacaa
     6781 catcaacaaa aaccagtctg cgctgtcgac ttctatcgag cgcctctctt ctggtctgcg
     6841 tattaacagc gctaaagatg acgccgcggg ccaggcgatt gctaaccgct ttacttctaa
     6901 catcaaaggt ctgactcagg ccgcacgtaa cgccaacgac ggtatttctc tggcgcagac
     6961 ggctgaaggc gcgctgtcag agattaacaa caacttgcag cgtattcgtg aactgaccgt
     7021 tcaggcctct accggcacga actctgattc cgacctgtct tctattcagg acgaaatcaa
     7081 atcccgtctt gatgaaattg accgtgtatc tggtcagacc cagttcaacg gtgtgaacgt
     7141 gctgtcgaaa aacgattcga tgaagattca gattggtgcc aatgataacc agacgatcag
     7201 cattggcttg caacaaatcg acagtaccac tttgaatctg aaaggattta ccgtgtccgg
     7261 catggcggat ttcagcgcgg cgaaactgac ggctgctgat ggtacagcaa ttgctgctgc
     7321 ggatgtcaag gatgctgggg gtaaacaagt caatttactg tcttacactg acaccgcgtc
     7381 taacagtact aaatatgcgg tcgttgattc tgcaaccggt aaatacatgg aagccactgt
     7441 agtcattacc ggtacggcgg cggcggtaac tgttggtgca gcggaagtgg cgggagccgc
     7501 tacagccgat ccgttaaaag cactggatgc cgcaatcgct aaagtcgaca aattccgctc
     7561 ctccctcggt gccgttcaaa accgtctgga ttctgcggtc accaacctga acaacaccac
     7621 caccaacctg tctgaagcgc agtcccgtat tcaggacgcc gactatgcga ccgaagtgtc
     7681 caacatgtcg aaagcgcaga ttatccagca ggcgggcaac tccgtgctgt ctaaagccaa
     7741 ccaggtaccg cagcaagttc tgtctctgtt acaaggctaa tggccttaac ctgcctgacc
     7801 ccgccaacgg cggggttttt tctgcccgca atttaccggt aacccccaaa taacccctca
     7861 tttcacccac taatcgtccg attaaaaacc ctgcagaaac ggataatcat gccgataact
     7921 catataacgc agggctgttt atcgtgaatt cactctatac cgctgaaggt gtaatggata
     7981 aacactcgct gtggcagcgt tatgtcccgc tggtgcgtca cgaagcattg cgcctgcagg
     8041 ttcgactgcc cgcgagcgtg gaacttgacg atctgctaca ggcgggcggc attgggttac
     8101 ttaatgccgt cgaacgctat gacgccctac aaggaacggc atttacaact tacgcagtgc
     8161 agcgtatccg tggcgctatg ctggatgaac ttcgcagccg tgactgggtg ccgcgcagcg
     8221 tgcgacgcaa cgcgcgtgaa gtggcacagg caatagggca actggagcag gaacttggcc
     8281 gcaacgccac ggaaactgag gtagcggaac gtttagggat cgatattgcc gattatcgcc
     8341 aaatgttgct cgacaccaat aacagccagc tcttctccta cgatgagtgg cgcgaagagc
     8401 acggcgatag catcgaactg gttactgatg atcatcagcg agaaaacccg ctacaacaac
     8461 tgctggacaa taatctgcgc cagcgggtga tggaagccat cgaaacgttg ccggagcgcg
     8521 aaaaactggt attaaccctc tattatcagg aagagctgaa tctcaaagag attggtgcgg
     8581 tgctggaggt cggggaatcg cgggtcagtc agttacacag ccaggctatt aaacggttac
     8641 gcactaaact gggtaagtta taacgtcagt aaatgccgca ctttaatttt gactaccagg
     8701 agttcttaat gatggtgcag cacctgaaaa gacggccatt aagccgctat cttaaagact
     8761 ttaaacacag ccagacccat tgcgcgcatt gccgtaaatt actcgatcgc attaccctcg
     8821 ttcgcgacgg caaaatagtg aataaaatcg agatttcccg cctggacacg ctgcttgatg
     8881 aaaatggctg gcaagtggaa caacaatcat gggcggcatt gtgccgattt tgcggtgatt
     8941 tacattgcaa aacgcagagt gattttttcg atattatcgg ctttaagcaa tttctttttg
     9001 agcaaactga aatgagccct ggtacggtgc gtgaatatgt cgttcgtctg cgccgtttgg
     9061 ggaatcatct acacgagcaa aatatttccc tcgatcagct gcaggacggt ttcctcgatg
     9121 aaatcctcgc cccgtggctg ccctccacca gcaccaacaa ttaccgcatc gcgttacgga
     9181 agtatcaaca ctatcagcgt caaacgtgta ccggacttgt gcagaaatcc tccagcctgc
     9241 ctgcttctga tatatattaa ataagaataa gatgtagcgg agttgttttt gtgtttacaa
     9301 acaatggctc tacactgcaa acagacataa caacattcgg ggtgaatatg aaattagcac
     9361 atctgggacg tcaggcattg atgggtgtga tggccgtggc gctggttgcg ggtatgagcg
     9421 ttaaaagttt tgcagatgaa ggtctgctta ataaagtcaa agagcgcggc acgctgctgg
     9481 tagggctgga aggaacttat ccgccgttca gttttcaggg ggatgacggc aaattaaccg
     9541 gttttgaagt ggaatttgcc caacaactgg caaaacatct tggcgttgag gcgtcactaa
     9601 aaccgaccaa atgggacggt atgctggcgt cgctggactc taaacgcatt gatgtggtga
     9661 ttaaccaggt caccatttct gacgagcgca agaaaaaata cgatttctct accccgtaca
     9721 ccatttctgg tattcaggcg ctggtgaaaa aaggcaacga aggcaccatt aaaacggctg
     9781 atgatctgaa aggcaaaaaa gtgggtgtcg gtctgggcac caactatgaa gagtggctgc
     9841 gtcagaatgt tcagggcgtc gatgtgcgta cctatgatga tgacccgacc aaatatcagg
     9901 atctgcgcgt aggccgtatc gatgcgatcc tcgttgatcg tctggcggcg ctggatctgg
     9961 tgaagaaaac caacgatacg ctggcagtaa ccggtgaagc attctctcgt caggagtctg
    10021 gcgtggcgct gcgtaaagga aatgaagacc tgctgaaagc ggtgaatgat gcaattgcgg
    10081 aaatgcaaaa agatggcact ttgcaagccc tttccgaaaa atggtttggt gctgatgtga
    10141 ccaaataatc agcataatga caaaaaaggg cgctttcact agcgcctttt ttatttacgc
    10201 gttttcagcg tgcataataa gaaaatcaca acaacacaca tcggaggctg ttatgccact
    10261 gcataattta acccgttttc cacggctgga gtttattggc gcgccaacgc cgctcgaata
    10321 tctgccgcgc ttttctgatt atcttggacg ggaaattttc atcaaacggg atgacgtcac
    10381 tcccatggca atgggcggca ataaattacg taagctggaa tttctcgcgg cagatgctct
    10441 gcgtgaaggt gccgatacgc tgattactgc cggggcgatc cagtctaacc atgtgcgcca
    10501 gactgccgca gtcgctgcga aactcggtct gcactgcgtg gcgctgctgg aaaatcctat
    10561 tggtacaacc gcggaaaact atttaaccaa cggcaatcgt ttgttgctgg atctgttcaa
    10621 tacccagatt gaaatgtgcg acgcactgac cgatcccaat gcccaactgg aagagctggc
    10681 gacgcgagtc gaagcacaag gctttcgccc gtatgtcatt ccggttggcg gttctaatgc
    10741 tttgggcgcg ctgggttatg tggagagtgc gctggaaatc gcgcaacagt gtgaagtggc
    10801 ggttaatatt tcgtcggtgg tggtcgcatc gggcagtgcc ggaactcacg ccggactggc
    10861 tgttgggctg gaacagctga tgcctgaaag cgaactgatt ggcgtgactg tgtcgcgttc
    10921 agttgccgat caattgccga aagtggttaa cctccaacag gcgattgcga aagaactgga
    10981 gctgaccgca tcagcggaaa ttttactctg ggatgactat tttgcacctg gctacggcgt
    11041 gccgaacgac gaaggcatgg aagcagtgaa attgctggcg aggctggaag gcattctgct
    11101 tgatcctgtg tataccggaa aagcgatggc ggggctgatt gacggtatca gtcagaaacg
    11161 cttcaaagat gaagggccga ttttgtttat tcataccggc ggtgcgcctg cgctgttcgc
    11221 ctatcatccc cacgtttagc tccgggaacg ctcatgcaag aaagtataca actggttatt
    11281 gattccttgc cgttcctgct gaaaggggct gggtatacgc tgcaactcag tatcggaggc
    11341 atgttttttg gcttactgct cgggtttatt ctcgcgctga tgcgcctgtc gccaatctgg
    11401 cccgtgcgct ggctggcgcg tttttatatc tctatttttc gtggtacgcc gctcatcgca
    11461 caactgttta tgatctatta cggactgcca cagtttggta tcgaattaga tcccattccg
    11521 tcagcaatga ttggtctgtc gctgaacact gccgcctatg ctgctgaaac gctgcgcgcc
    11581 gccatttctt ctattgataa aggtcagtgg gaagctgcag ccagtattgg tatgacgcca
    11641 tggcagacca tgcgtcgcgc gattttgcca caggcggcgc gggtggcgtt gccgccgctg
    11701 tcgaacagct ttatcagcct ggtaaaagat acgtcgctgg ccgcgacaat ccaggtgccg
    11761 gagctgttcc gtcaggcgca gttgattacc tcgcgcacgc tggaggtgtt caccatgtac
    11821 ctggcggctt cgctcatcta ctggatcatg gcgactgtgt tatcgacgtt gcagaaccat
    11881 tttgagaatc aacttaatcg ccaggagaga gaacccaaat gagtgccatt gaagttaaga
    11941 acctggtgaa aaaattccac ggtcagacgg tgctgcatgg tatcgacctt gaggtgaagc
    12001 caggcgaagt agtggcaatt atcggtccga gtggttccgg caaaaccacg ttgctacgca
    12061 gcataaatct gctggaacaa ccggaagcgg gaaccatcac cgttggcgat atcactattg
    12121 atactgcacg ttcattaagt cagcaaaaat cgctgattcg ccagttgcgt cagcacgtcg
    12181 ggtttgtctt ccagaacttt aatctgtttc cgcatcgtac ggtgctggaa aacattattg
    12241 aagggccggt gatcgtcaaa ggcgaaccga aagaagaggc cacggcgcgc gctcgcgagc
    12301 tgctggcgaa agttgggctg gccggtaaag aaaccagtta tccacgtcgt ttgtctggcg
    12361 gtcaacagca gcgcgttgcg attgcgcgtg ctctggcaat gcgtcctgaa gtgattttgt
    12421 ttgacgagcc aacgtcggcg ctggatccag agctggtggg cgaagtcctg aacaccattc
    12481 gtcagctggc gcaggaaaag cgcacgatgg tgattgtgac gcacgaaatg agctttgccc
    12541 gggatgttgc ggaccgggcg atttttatgg accaggggcg gatagtcgag cagggggtag
    12601 caaaagcgtt atttgctgat cctcagcagc ctcgcacccg ccagttcctg gagaagtttc
    12661 tgctgcaata ataagaaaaa atcagccccg acgattcacc agtcggggcg ggacgccatt
    12721 tcaaacgtga taaaactgct taacaaa
//
LOCUS       DAPOXO010000119        11896 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.119, whole genome shotgun sequence.
ACCESSION   DAPOXO010000119 DAPOXO010000000
VERSION     DAPOXO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11896
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.119"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(208..975)
                     /gene="fecE"
                     /locus_tag="ROH59_004451"
     CDS             complement(208..975)
                     /gene="fecE"
                     /locus_tag="ROH59_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="HDX4806855.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(976..1932)
                     /gene="fecD"
                     /locus_tag="ROH59_004452"
     CDS             complement(976..1932)
                     /gene="fecD"
                     /locus_tag="ROH59_004452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease
                     subunit FecD"
                     /protein_id="HDX4806856.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            complement(1929..2927)
                     /gene="fecC"
                     /locus_tag="ROH59_004453"
     CDS             complement(1929..2927)
                     /gene="fecC"
                     /locus_tag="ROH59_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="HDX4806857.1"
                     /translation="MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            complement(2924..3826)
                     /gene="fecB"
                     /locus_tag="ROH59_004454"
     CDS             complement(2924..3826)
                     /gene="fecB"
                     /locus_tag="ROH59_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="HDX4806858.1"
                     /translation="MLAFIRFVFAGLLLVISHAFAATVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            complement(3871..6195)
                     /gene="fecA"
                     /locus_tag="ROH59_004455"
     CDS             complement(3871..6195)
                     /gene="fecA"
                     /locus_tag="ROH59_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate transport protein FecA"
                     /protein_id="HDX4806859.1"
                     /translation="MTPLRVFRKTTPLVNAIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLTSRSTVLMDGIPVPFAPYGQPQLSLAPVS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYVNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHKEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            complement(6282..7235)
                     /gene="fecR"
                     /locus_tag="ROH59_004456"
     CDS             complement(6282..7235)
                     /gene="fecR"
                     /locus_tag="ROH59_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fec operon regulator FecR"
                     /protein_id="HDX4806860.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSE
                     TGEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRILTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            complement(7232..7753)
                     /gene="fecI"
                     /locus_tag="ROH59_004457"
     CDS             complement(7232..7753)
                     /gene="fecI"
                     /locus_tag="ROH59_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="HDX4806861.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
     gene            8045..8742
                     /locus_tag="ROH59_004458"
                     /pseudo
     CDS             8045..8742
                     /locus_tag="ROH59_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558153.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(8902..9033)
                     /locus_tag="ROH59_004459"
                     /pseudo
     CDS             complement(8902..9033)
                     /locus_tag="ROH59_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            9315..10673
                     /locus_tag="ROH59_004460"
     CDS             9315..10673
                     /locus_tag="ROH59_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase-like activity of phytase family
                     protein"
                     /protein_id="HDX4806862.1"
                     /translation="MKRKIIPVLIGCTLSFSALAAQPTAERYVVSFPEGTHVNYAGAF
                     ASAFPNGLPVGIGSGLLFTGKQGDALTFATITDRGPNADSPKEGKNETKIFVTPDFAP
                     LLMTIRVQNGKAEAIDPRPLHDDKGAINGLPLASDVIGSTNEVAFSDTLHRLKGDNRG
                     LDTEGITPDGKGGYWLCDEYGPFLINIDSKGKILAIHGPQAAEGEKAIAGGLPNILKW
                     RQANRGFEGLTRMPDGRIIVAVQSTLDIDAKSKKKALFTRLVSFDPASGKTAMYGYPI
                     DSAAYSKNSDAKIGDIVALDNQHILLIEQGRDKNNRMRNLIYEVDLNKASDLSGFDKP
                     GEYPEFDDEKTLSQRGITLAQKTQVVDLRSLGWQQEKAEGLALIDSKTLAVANDNDFG
                     VKVAMQHPVEGKTFKDYRVNAEGKLTLDDKQVETTLRVKPLEKPESDSELWIVTLPEA
                     LK"
     gene            complement(10912..>11896)
                     /locus_tag="ROH59_004461"
     CDS             complement(10912..>11896)
                     /locus_tag="ROH59_004461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDX4806863.1"
                     /translation="AEQLELMRSAFRVIRTVREKHACTQCDAIVQAPAPSRPIERGIA
                     GPGLLARVLTSKYAEHTPLYCQSEIYGRQGVELSRSLLSGWVDACCRLLSPLEEALHG
                     YVMTDGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKG
                     IHPQTHLACFSGVLQADAYAGFNELYRNGGITEAACWAHARRKIHDVHVRIPSALTEE
                     ALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKTLFFGSGHGGE
                     RGALLYSLIGTCKLNDVDPESYLRHVPGVIADWPVNRVSELLPWRIALPAE"
BASE COUNT         2662 a         3276 c         3368 g         2590 t
ORIGIN      
        1 tgatcacgac tggtttgaaa gccgcgccca agcctgtaca gctctggttt gcgttgatta
       61 tgaacctgtc agcctaaagc aagcggatgg acgatgagta ttggtaatct ttcagagtcc
      121 ggaaaagttc agccccagtc tgaacaggct tgctggcgcc agtccagttt cattcagtcg
      181 tggtttggtt cttacggcct gtgcaatcta cctcattagg cacatcggcc tgccagatac
      241 cggctcgggg tgtatttccg cttccacgct gaatactgtt ctcagcaatc ctggggtcat
      301 cacctcttct ggtgtgcctt gcgccataac atgtccgttt gccattacca ccagttgatc
      361 gcagtaccgg ctagcctgat taaggtcgtg cagcacagcg accaccgttt tcccctgagt
      421 ccggagttcg cccatcaacc gcatcaggtc cacctggtga ttgatatcaa gataggtggt
      481 tggctcatca agtaatacaa cgggcgtatt ctgggccagg accattgcca gaaatgcgcg
      541 ctggcgctga ccgccggaaa gctcggttaa ccgacgaacg gcaagatgat tgatccgggt
      601 ctggttcatg gcgacattaa ctcgtgcatt gtcttcagcg gagagacgcc cccagagtga
      661 cagccaggga ttacgaccat acgaaaccag ctcctggact gtgatcccct ctggcgttaa
      721 atggtgctga ggcagcagcg aaagcctgcg ggccaactgg cgcgatgaga gcatatttat
      781 gggattatcg ccgagaaata cggtgccaga ctgcggcatt aaaagccgcg aaaaacagtt
      841 taacagcgtc gatttcccgc aaccgttagg accgatcagg gcggtgatct tccccgttgg
      901 cagtgagagt gaaacgtcgt taagtacctt gtctgtcccg taactgaccg tcagattttc
      961 agttcgtaaa gtcatttatc gcattctcac aagcaaccag acaaaccacg gcgcaccgat
     1021 aatggcggtc agcacgccaa ccgggagctc cagtggggga tgaataattc tcgccagcag
     1081 atcggcaacc accaacagca acgcacctgt cagggccgaa acaggcagca gtctgcggtg
     1141 acgtccaccg gtgatgctac gcatcatatg cggcaccacg agaccaataa agctaatcgg
     1201 gccgcaggcg gccacgccgg tagatgtcat ggcgacagct agtaacaaag cccagaatcg
     1261 ggtatggggc accgacacac cgagcgtggt ggcgcgcgca tcgccgagtg caaggaggtc
     1321 gagatcgcgg caaaaactca ggctcagcgg cagaaataaa atcatcagcg ggatggcaat
     1381 cttcacaaag ctccagtcac ggccccataa gctgccggtc agccacagca gggcgttgtt
     1441 cacatcctgc gggcgcgaga gcatcagata atccgtcagg ctggcccagc atgcagaaag
     1501 cgccacgccg gtgagcgcca gcttcatcgg ctggtgggtc tttgccagca tcttcagcaa
     1561 tatcaacccc gccatgccgc ccgcaaaggc cagcagcggc agcaccatca cgggcagtga
     1621 cggcataaga agtagagccc ccacagaggc caggctggcg gcatggttaa caccgagaat
     1681 atccggtgat gccagagggt tgcgcacaat cccctgtatc agcacgcccg ccacggcgag
     1741 ggctgcaccg acaaacagtg ccagcagcaa gcgcggcagt cggtactcca tcaatacata
     1801 ataatgctcg cgtccggcct gccagtcggt cagcagcgcg cgccacggca cggggatcac
     1861 tcccatatgg agtgataaca gcgcacagcc cgccagggca agggtgatga aaataaccag
     1921 cgcaattttc atcctcgcct cctcacaagc cagacaaagc aagggctgcc aatcagcgcc
     1981 agcactgcgc ctgcgggcag atctccgggg aaggccagtg cgcgtgcgag tacatctgcc
     2041 agcagcatca gcgtggcccc cagcagcatg ctcactggca gtacgttgcg ctgatcgaag
     2101 cctgcccaga agcgcgccag atgtggcacc agcagaccga taaacgccac cggacctgcc
     2161 acgctgacgc acgcaccaac cagaagcagc actaacatat tgatgaccaa acgtagcctc
     2221 gtcaggttca ctcccagcgt atgggcggtg ctgtcgctga ggttgagcag gttcagttga
     2281 ttcgccagca gcaacacgac agggactgca gtgaccacca ccggcaagag ctgccagaca
     2341 tcctgccagc gggcgtggga cactccgcct gccagccagt aaaagatgcc gtaagcatga
     2401 tcttcggcca gcagcagggt gatgcgggta aggcccatac aaaaggccga cagcgcgata
     2461 cccgcgagga tcagtttgtt tctgtcatgg gtatgacgaa atccgcctcc tgcggtcatg
     2521 accagcagcc agctcacgcc gcccccgcat gccgcgatga acgacagaga atagcctgca
     2581 atcggcgtcg gactcagcgc gctggtaagc gccatagcca gcgccgcgcc gctgttaatg
     2641 ccgagcagtg aaggagaggc cattgggttg tgggtcaggg tttgcagcag cgtgcccgcg
     2701 agcgccaggc ttgcgccgat cagaacggcg accaggcttc gtggcaaacg aaggttttgc
     2761 accagcgctt ctggtagcgt tggcgtgtgt ccaggcagca gggcgcgggt tgcatctgct
     2821 ccggaaacag gaatggccga gtagcaaaac agactcagcc agaaaataat aataagtgct
     2881 gcaacgggaa gcccccacag cagcaccggg tgttttatcg cggtcatttc acaacggtaa
     2941 gcggctgatg gtggaagatt tttaccgtgt cagcggcaat acgctctgca gcaaaaatac
     3001 cgcgcatccg cgcccaggtg ttactgtcga ccgaagcaac ctgctgcttc tgcgcggcgg
     3061 ttaacatctg ccagagcgga tcttgttgcc agcgtttaac aatgctctct tcgcgatagt
     3121 gggcaaccag cagccaggca ggattgaccg ccagcagttg ctccaggccg atggacggca
     3181 tggacgcacc cgccatcgca gcgggaacgt tcagccccag agaggccagc acgctgccgg
     3241 tccaggtctc ctgagtatgc aggttgaatt gctgttcgcg tgatgtgcca aaggccacgc
     3301 gtgtcccttt gggaagctgg ctggcccact gcgccatcct ctctttatgt tgttccaggc
     3361 gtgcctgcat ctctcgcttt ttacccacca tttcgccgat gatagccgca gattgcaaat
     3421 tttcagcgta ggtttcgttg cgggacttaa gcagcagtac cggcgcgatt tgctgcaagg
     3481 cgatgtaaac ccccgcatgg cgactgctgt cggcaatgat caggtctggt ttcagagcgg
     3541 caatggcttc caggctcggc tgcgcgcgcg ttccgacgga ctgccacggt ttcaggtgcg
     3601 cacgcacttc gggcaggatg cgttttgcat cgttatcgtc ggcaataccg atcgggctga
     3661 cgtccacggc ggccagcgca tcggcgaacg agagttccag caccacaatc cgttgtggcg
     3721 ttttttcgag tgtaaacgtg ccgtgttcgt cctgaaccgt ggcggcaaag gcgtggctga
     3781 tcaccagcag caggcctgca aaaacaaaac ggataaatgc caacataatc acattccagc
     3841 taaaagcccg gcaagccggg cgttaacaca tcagaacttc aacgacccct gcatatacag
     3901 cgtgcgcggc tggcctgcat agatgccttt gttgttgtcg tcataagagc ggatgaagta
     3961 gtcctggtcg aagatgtttt tcacaccgaa tgccaggttc agatctgcca tctgcgggcc
     4021 aaagtcatac gccacgcgtg cgccccagag catgaagccg ggaatgcggc cggtactgcc
     4081 gtcggcgctc tctttcaccg tattggcgtt atccgcaaac tggctggact ggaaatcgct
     4141 gttcagattg aacgtccagt ttcctggctt gtagtccacg cccagcgtgc ctttatgttt
     4201 cggggagaat ggtaccagat tgccgtaggt gtcgcctttc tcgcggattt ccgcgttcac
     4261 atacgcatag ctggcgtaga tggaaacgtt atcaagcgtt ggcgttagcg tacccagatc
     4321 gtaacgtgcc tgcgtttcca gcccggtatg gcgcgttttg ccacgtgcag tgacggtgtc
     4381 gttggtctgg ttggagtcgt actgattgtt aaagttaatc aggaacagcc ccatttccgc
     4441 cgtcagcgcg ccgtcgtcgt agcgggtacc gagttcccag gttcgcgctt tttccggttc
     4501 cacattgccg ctttgcacag ccttgccaat ctggctgtac tgtacggtgc cgaacgagcc
     4561 ttcagtgttt gcataaagat tccagctgtc agtcaggtga tagagcacgt tcaacgccgg
     4621 aagcggtgcg ttatagctca cttctttgtg cgtgcctgtg atggcgttgt tctggtatga
     4681 ctcgatatgt tcgaaacgca tacccggcgt gatggtccag ttgccgatgt cgattttgtc
     4741 atccagatac caggcgtgcg cctcggtgcc ggaacgcgta tcgcggtcgt aagggcttga
     4801 gccggacggc aactgcccgc tgctggtggc ggtgtagtaa cgcatttcat gcgttgattc
     4861 attcacatag cgatagccca cgcccacttc gtgcgcggaa gggccgatca taaagatctg
     4921 gctgtagcgt ggctcaatac cgcgcaccca gtagttacgc ggcgagaggg tgatgcgttt
     4981 gccttgctcc aggtagccgc tgcgcagggt ttgggtgtag aacccctgaa tgttgaattt
     5041 atgctggctg tctggctgga actggtagcc caggctcgcc agcttgcgac gaccccagaa
     5101 gcggtcatac gggcgggtgg attgccagcg atcggcgtcg taatccgcgc gagacaggcc
     5161 accgggcatg tcggcttcac cgtcgtaata ttgcagcagg ctgttgaagg tgtgcacctc
     5221 atccggcgca tatttgcttt tcagcatcag gtcgtcgatg cgggtggcgc tgtgctcgcg
     5281 ccagtcactg ccgcgcgtgc cggagtagag cagcgcggtg ccaaaaccgt tgtccgctgt
     5341 gccgcccacc atcaggttgt gcgtctcttt cgggttgttt tgtgaagagg ttgggctgag
     5401 ctgaccttcc acgcccgcct cgataccaaa gtcctgcgga atggcacggg taacaaagtt
     5461 caccacgccg cccacgctct gcggtccgta acgcaccgca ccaccaccgc gtaccacgtc
     5521 aatggcatcc atgttgccga gcgaaacggg agccagtgaa agctgcggct gaccgtaagg
     5581 ggcgaagggg acggggatgc cgtccatcag gacggtcgag cggctggtga ggcgcgggtt
     5641 caggccccgg atgccaaagt tcatcgccag gtcgtggctg ccggtgccgt tgttttccgg
     5701 cgcgctgacg ccagggatgc ggttaagtac ctcacgcatg gtggttgcgc cggttttggc
     5761 gaaatcctca cggcggatca cgtcacgcgc gccagcatgt tcaaatacgt cgttttcacg
     5821 cgcatcaccc agccagtcgc cgaccacggt cagggcatct tcttttggtg cgggcgcggg
     5881 ctccagcgtc cagctattat ttcccagcgg ttttacctgc agtccgctgc cgtccagcag
     5941 ttgttgcagg ccgctctcga cgtcgtaatc gccgtgcagg ccgttgctct gcttgccgcg
     6001 cgtcaggctg gcgtcaaccg agagggtaaa tccgctgtgt gcggcatact gattgagcgc
     6061 tttatcgagc gatcccggtg cgatattaac ctgtgcagca aaagcggaaa acgagagacc
     6121 ggccagcggc agcaggctca ggcgaatggc gttaaccaaa ggtgttgttt tacgaaaaac
     6181 gcgtaacggc gtcatacctt ccccatcatc atttttgttg tgttcagcta tgagtcgaac
     6241 gagaagggta aaaaggacaa tcgaaataag aattattttc cttacagtgg tgaaatgttt
     6301 atccagtacc gcgtaataga ctgaatttta acgggaagcg tttgcgcgat aacgttcagg
     6361 atcgcatcgg tatttttcag cgggaacgtc ccgctcaggc gcagcccggc aacggcggga
     6421 tcgcagcgca gcacgccgtt gcggtaacgg gttagcgtgg ctatcacctc acccagtggt
     6481 ttatcgctga agctcaggat gtccttcgtc cagcttgtac tctcgtcatc cagcggtttc
     6541 actgcgccaa actcagaggc gctgaactgc aggctttcac cagcgttcac gatgcgtttt
     6601 tgcgcggggg cactggcgag aagcacttcc acagcgtgct gctgaacgtc aagctgcgtg
     6661 aaattatcct gctggcggac ggtaaattct gtccctaaag cagtgagctg gccctgacgg
     6721 gtcaggatac ggaaggggcg ttgcagggca tctttcgcgg tagtaatggc gatttcaccg
     6781 taccagagcc ggacggtgcg ctgatgcgca tcaaaacgca catccgccgc gctttgggta
     6841 ttcagcgtga gcagggagcc atcttccagt tgctgacggc tgactgtgcc tttggcggtg
     6901 cggtaatctg cccgcagacc ttcgccggtt tccgactgcc agagctgcca gcctccgcca
     6961 gcgccgagca acagcagtaa tcctttcatc acgtgacggc gggtgaggcg ggtatcgtgc
     7021 aacgcccggc tggcaacgtc gccaggcaca ccgccaagct ggttgcgcag gttttcaacc
     7081 tgctgccagg cccactggtt atcctgatcc tgttcatacc actgttgcca gcgcgcttcc
     7141 tgttgtgggc tgacgcgctc gccgcttagc acggcatacc agtgggaagc tgaacgcagc
     7201 gcctgacggc gggaatcggt taacaaagga ttcataaccc atactccaga cggaacagca
     7261 ggcagtgctc gacggctttc gccacgtatt ttttcacgga gctgatggaa acaccgagtt
     7321 tgtgcgcaat ctcgctgtat gtcagaccat ccagttgcga aagcagaaac gcttcacgtg
     7381 ttttgccgtt tagcccgtcc agcatgctgt cgaggagttg tagggtctcg agttggcttt
     7441 cgcgttcctc aggtgaaggc gctcccccct ccggcataag cgccagcatc tccagatacg
     7501 ctttttccag cgcgtttcgg cgaaacaggt ccaccatcac gcgtttggcg atagtgcaga
     7561 ggaaggagcg aggatcgcgg atcgtcgaga gcgtttcgct gaccattacc cgcaaaaaag
     7621 tgtcctgggc aatgtcatct gcatcaaaag cagactggag tttgcgcgtc agccagcttt
     7681 tcaaccagcc gtgatgtgtg ccataaagcg actcgaacgt taaggaagct gtggtagtgg
     7741 cgcggtcaga catgcggagt gcatcaaaag ttaattatca cgtagtcata ttaatatgag
     7801 aatggttatc attacaattg gaaataaaat tgtttccaat agacattttt aacatgttgt
     7861 ttttctaagt gttataaggt aggtataaaa tgggatggag cctctgcttc tggcatgtgt
     7921 cggtcagaat gactcatgat gtggtctgct attattgaca tcctcactgc cctaaaggat
     7981 ggggatttcg gtaatgctgc caacttactg atttagtgta tgatggtgat tttaaggtgc
     8041 ttgcgtggct tccatttcca tcagatgtcc ttcctgctcc gctactgaag gcgtggtgcg
     8101 taacggcaaa agcactgccg gacatcagcg ctatctctgc tctcattgcc gtaaaacatg
     8161 gcaactacag ttcacttaca ccgcctctca gcccggtacg caccagaaaa tcattgatat
     8221 ggccatgaat ggcgtcggat gtcgcgccag tgcacgcatt atgggcgttg gcctcaacac
     8281 ggttttacgt cacttaaaaa actcaggccg tagtcggtaa cctcgcgcat acaaccgggc
     8341 agtgatgtga ttgtctgcgc tgaaatggac gaacagtggg gctacgtcgg tgctaaatca
     8401 cgtcagcgct ggctgtttta cgcgtatgac aggatacgga ggacggttgt ggcgcacgtc
     8461 ttcggtgaac gcactctggc cacactggag cgtcttctga gcctgctgtc ggcctttgag
     8521 gtcgtggtat agatgacgga tggctggccg ctgtatgaat cacgcctgaa gagaaagctg
     8581 cacgttatca gcaagcgtta cactcagcgc attgagcgac ataatctgaa tctgagacaa
     8641 catctggcaa ggctgggacg gaagttactg tcgttctcaa aatcggtgga gctgcatgac
     8701 aaggtcatcg ggcattatct gaacataaaa cactatcagt aagttggagt cattacctcc
     8761 tcccgaactc aaagctatca tacagataat tactggttaa ccctatatag ggcattttaa
     8821 agtgtgatct tatccagcaa taatggacac gcggctaagt gaaccgcccc gggtttcctg
     8881 gagagtgttt tatctgtgaa ctcaggctgc cagatcatcg tttccgatgg aagcataata
     8941 agctttttct gcttctgccg gtgggatatg gccctgcctt tccagcaatc gtcgattgtt
     9001 ataccagtcc acccacgtga gtgtggtcag ctcatcatac tgacacgtgc attaccccta
     9061 ccgcgataat gcaaccgtac aatatagggc gtttcctaaa cgcagccctc atcactccaa
     9121 tccaacaaga cacagcattt ttgatcacga agaaagacaa ataatttccg taaatgtttc
     9181 cgttgttaca aataacaaca gtgttttaca tttctttggc ctcaggcccg cgcatgttgc
     9241 cattcgatgt cattttcctg actcgtttct tctttatggt gtagtgtgat cttcacttta
     9301 tggatgctaa caatatgaaa agaaaaatta ttcccgtgct aatcggttgt acgctctctt
     9361 tctctgccct ggcggcacaa cctacggctg agcgctatgt cgtcagtttt ccagaaggca
     9421 cgcacgtgaa ctacgccggc gcatttgcca gtgcattccc gaacggcctt ccggttggga
     9481 taggttctgg cctgctgttc accggtaaac agggcgatgc cctgacattc gcaaccatta
     9541 ccgatcgcgg tccgaacgcg gattcaccga aagaggggaa aaacgaaact aaaattttcg
     9601 ttacgccaga tttcgcgccg ctgctgatga cgattcgtgt acaaaacggc aaagcggagg
     9661 ccatcgatcc ccgtcctctg catgacgata aaggcgcgat caacggtctg ccgctggcaa
     9721 gcgacgtgat tggctccacc aatgaagtgg ccttcagcga cacgttacat agactgaagg
     9781 gggataatcg cgggctggat acggaaggga tcactccgga tggtaaagga ggttactggc
     9841 tgtgcgatga gtatggcccg ttcctgatta acatcgacag taaagggaaa atcctggcaa
     9901 tccacggtcc gcaggcggcg gaaggggaaa aagcgattgc gggcggtttg ccaaatatcc
     9961 tcaaatggcg tcaggcgaac cgcggctttg aaggcctcac ccgtatgccg gacgggcgta
    10021 ttattgtcgc cgtgcaaagt acgctggata tcgacgctaa gagcaagaaa aaggcgctgt
    10081 ttacgcgtct ggtgagcttc gatccggcaa gcggaaaaac cgcgatgtac ggttatccta
    10141 tcgacagcgc ggcctacagc aaaaacagcg acgctaaaat cggagacatc gtggcgctcg
    10201 ataaccagca catcctgctg atcgaacagg gaagagataa aaacaacaga atgcgtaacc
    10261 tgatttacga ggtcgatctc aataaggcga gcgacctgtc aggcttcgac aagccgggtg
    10321 agtatccgga gtttgatgat gagaaaaccc tgtcacagcg cggcattacc cttgcgcaga
    10381 aaacgcaggt tgttgatctg cgctccttgg gctggcagca ggagaaggct gaagggttgg
    10441 cgctgatcga cagcaaaacg ctggcggtgg cgaacgataa cgactttggc gtgaaggtgg
    10501 cgatgcaaca tccggtcgag ggcaagacat tcaaggatta tcgggtgaac gcggaaggaa
    10561 agctgacgct tgacgacaag caggttgaaa cgaccctcag agtgaagcca ctggagaaac
    10621 cggagtctga cagtgaactg tggattgtga cgctgccgga agcgttgaaa taagtttata
    10681 aggtacggac agcagtatcg cttagttttt caaattcatg tatgtgaaca atattggggt
    10741 tccggcgtag acccccaatg aaagcgtcac cacgtgaaaa catgcctgca cggtttacac
    10801 gtcatctcat ggtggcagcc ggttaacttt cctgctacac cagtggaaaa aggccataag
    10861 cagtccgaac aaaagtaagc gtacagcgag ggccgtattg acggggatgt gttattcagc
    10921 tggcagtgct atgcgccacg gaagcagttc gctgacccgg ttgaccggcc agtctgctat
    10981 gacgccaggc acatggcgaa ggtagctttc tggatccacg tcattcagtt tgcacgtccc
    11041 gatcaggctg tacagtagcg ctccccgctc accaccatgg ccagagccga agaacagggt
    11101 cttcatcttt tcacgcaacc agctttccag ggatttcaac agcggtttcg tttttcgctg
    11161 acgttcagca agccgctgct ctgccggcat tccccttata tccgcctcta tggcgtacaa
    11221 ctgaccgatc tgctctaggg cttcttccgt cagtgctgac gggatgcgga cgtgcacatc
    11281 gtggatcttt cggcgggcat gagcccagca ggcagcttcc gttatcccac cattgcgata
    11341 cagctcgttg aacccggcgt acgcatccgc ttgcagcaca ccgctgaagc aagcaagatg
    11401 agtctgcgga tggatgcctt ttctgtccgg gctgtaagcg aaccacactg caggtgccaa
    11461 cgctgacccg gcattgcggt catcacgaac atacgcccac aaccgcccgg tcttcgtctt
    11521 cttattaccc ggcagcagta cctggaccgg ggtatcatcg gcatggagtt tgccgtcagt
    11581 catgacatag ccatgaagcg cctcttccag cggagacagc agccggcagc atgcatccac
    11641 ccagcccgac agcagtgaac ggctcagctc cacaccttgc cggccgtata tttctgactg
    11701 gcaatacagc ggggtgtgct ctgcatactt cgaggtcagc acgcgggcca gcagccccgg
    11761 tccggcgata ccccgctcga tgggccgcga aggtgcaggt gcctgcacga tggcatcgca
    11821 ctgagtacag gcatgttttt cccgtaccgt ccggataacc cggaaggcgc tacgcatcaa
    11881 ctccagctgt tcggcg
//
LOCUS       DAPOXO010000120        11845 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPOXO010000120 DAPOXO010000000
VERSION     DAPOXO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11845
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.120"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1201
                     /locus_tag="ROH59_004462"
     CDS             <1..1201
                     /locus_tag="ROH59_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX4806864.1"
                     /translation="LDLGKRAKVRQIIEHMWFQRKALLNGRNGNLSNTAWAALQSYTV
                     PESLTVDYKNRREPAVFNKTDNSEWLLVDSQLEQVEDLVELYAELKRGPKSAEAIQRF
                     AVVTFHQSYGYEEFIEGIRARSDESGNISYPIEPGIFMRLSQRANADPGHRYAIFIDE
                     INRGNISKIFGELISLIEVDKRAGMPNAMSLQLAYSGDHFSVPANVDIIGAMNTADRS
                     LALMDTALRRRFDFVEMMPDLSLLSGAKVKGIELESLLEKLNSRIEALYDREHTLGHA
                     FFMPVKNALDAGDEEAAFKQLKIAFQKKIIPLLQEYFFDDWNKIRLVLADNQKQDDNL
                     QFVIEKTDDLDTLFGNNHGLRHHDQQSTAYELKDFDQEIWNIPQAYRSIYQPQQTPLD
                     EQAVNHG"
     gene            1194..2480
                     /locus_tag="ROH59_004463"
     CDS             1194..2480
                     /locus_tag="ROH59_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDX4806865.1"
                     /translation="MGEVISVFEYDLLGSDKAASVGAKLVPPLVFNYLEALSLASNQG
                     SQFLKLTSRSGFKLLQVQNYAGMLSTPHGFQLEILPKVGKNLTAANARQTLLTMLSHL
                     PGFRHIETQQATLQAQRMPLLEIFIHQFLHSVSQLLKQGLRSDYVSEQGNLAFMKGKL
                     MLSAQLRHNAVNRHKFCVDYDDYMPDCAANRLLHSALDKLLSLKLSSENQRWLYELRF
                     AFDGIPLSRDIERDINNLRLERGMAHYNEPMAWAQLILRGMSPSALQGNTKAISLLFP
                     MEAVFESFVAQTLPYELPSHLKVIPQAATYSLVKHGSNDCFKLRPDLLIQSRRPVQTK
                     LVMDTKWKLINSNSQKTTQYGLAQADFYQMFAYGQKYLNGIGEMYLIYPAHDQFNQPI
                     QQHFAFSKTLKLWVVPYQITANRGERMMWVKDVSSI"
     gene            2590..4329
                     /locus_tag="ROH59_004464"
     CDS             2590..4329
                     /locus_tag="ROH59_004464"
                     /EC_number="3.1.21.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Alw26I/Eco31I/Esp3I family type II restriction
                     endonuclease"
                     /protein_id="HDX4806866.1"
                     /translation="MKMGKIAVTPNNDKAASHSKDENLATNTIKKNVKPKYGDAAFLE
                     YTRLIVNHPNYFGMPDPFGEKGEIQWEAPSNRASGKFKHTHQRRYEWWKNKARSIGID
                     PDTEKAWISKTAKLIHPLGVKPCKKCGKEMELSYSYPNEHFFSRVRKLNYIDETFELS
                     QNEHIVDLLTRLDDRFGERIYLDLPHLFSTKSITIPDISSNLEAWIEYLKEQYIPQES
                     RMLSPGAMANPPDRFDGFHSFNRCCRSIADKGRTKENLKSYVTDRRVFEYWVDGDWVA
                     ADRLMGQVRTNNIFINEECLNAGNGGLHPTPCQADHIGPISLGFSHRPQFQLLCKSCN
                     SAKNNRMYLSDIISLLEAENEGHTVISWFAEEVWNRLKHSVDDSEKALRLSKILRDNR
                     HTYMNLLKKIMDEGYYTFLASLLHLEVANYNPIFEGLCISNHLTHYKSLKKIKRESKY
                     AAVQKTRRIRIAFTSLNDYHRKENRNAFIVSNELSEKFFSEAMDNLKSLSEITSCLDE
                     KISGIISENSDSKNEFRTIITDLREIVTNNKEKFNLILKYLISGMSEIGKELESYWEN
                     DRYVRSIPEEFIE"
     gene            complement(4342..5532)
                     /locus_tag="ROH59_004465"
     CDS             complement(4342..5532)
                     /locus_tag="ROH59_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDX4806867.1"
                     /translation="MTKSETFMIPNHKAAKLSELDMMIVNSVPPGGNWKNIPLDVPSK
                     RIEQIRDSYAQGKGSRSTYYGRLLPDMPAYTINTYFNRPGNGCHIHYEQDRVLSQREA
                     ARLQSFPDDFIFFGGQTAINTQIGNAVPPFLAFLIAKEIEKAIGNTGYYIDLFSGAGG
                     LGLGFKWAGWTPLLANDIEEKYLQTYSNNVHKEVLCGSISDNETFSKIADKISGFKKL
                     YFDKQLWILGGPPCQGFSTAGNARTMDDPRNSLFMHYKSLLNEIKPNGFIFENVAGLL
                     NMEKGKVFERVKEEFSSTMKTMNGWILNSEHYAIPQRRKRVILVGSNDPLFSIEPPQK
                     LTEDKESWVSVKDALSDLPPLQHGEDGSGKYYIHHPENDYQLFMRGNITPSEYYERNI
                     KPSL"
     gene            complement(5525..7165)
                     /locus_tag="ROH59_004466"
     CDS             complement(5525..7165)
                     /locus_tag="ROH59_004466"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Alw26I/Eco31I/Esp3I family type II restriction
                     adenine-specific DNA-methyltransferase"
                     /protein_id="HDX4806868.1"
                     /translation="MEEIFYMKHIHLINSLSLDETTKFTKKATGKYYTDPKIALLMIE
                     KLLPLINSCDKKSYNVADPFSGDGRLITLLIKQWMINGFPDVEWNVYLFDIENTGLTY
                     AKNALSELKLAGANINITIKNSDVFYEFKKYVDYFDCVITNPPWENIKPDSRELDFFE
                     PSMKSMYIDSLREFDDYLSRVLPYSQPKRKFAGWGTNLSRVGAELSLEICNKNGLVAI
                     VMPASFFADEQSYILREKFFNSGRIDCINYYPAEAKLFGGADVSSCSFIFNKGESLND
                     NIQLSVYDKNLNIKSLGFFDLSSIDSQYLSIPVSQGVHAVHLLRKLQEGYPTWGSLEK
                     NGEIWAGREIDETGSSDWTQKSGGGLLFIKGKMIGRYNFHNEKSLRITKKIDKVLSNS
                     NFVRIAWRDISRPSQKRRMIATIIPPNSLAGNSLGVVYYKSGSQDSLFSLLGIINSLC
                     FEFQLRSFLATGHVSLSALRKTAIPSEKILLQHSELKQLVISCIEGCCDAELKIEAYV
                     AKNIYKLDLNEFNKLLSSFDKIELAEKESLLRIFQHYD"
     gene            complement(7938..8114)
                     /locus_tag="ROH59_004467"
                     /pseudo
     CDS             complement(7938..8114)
                     /locus_tag="ROH59_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(8478..8636)
                     /locus_tag="ROH59_004468"
     CDS             complement(8478..8636)
                     /locus_tag="ROH59_004468"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806869.1"
                     /translation="MMMSDTTLSRPEVVSGHTDVIYSTSVCHILAVRKSTLLPIDTII
                     RHQVSDIS"
     gene            complement(8736..8912)
                     /locus_tag="ROH59_004469"
     CDS             complement(8736..8912)
                     /locus_tag="ROH59_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDX4806870.1"
                     /translation="MKSLTTETALDILITWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IAQAREGIRTLRQQ"
     gene            complement(8929..9417)
                     /locus_tag="ROH59_004470"
     CDS             complement(8929..9417)
                     /locus_tag="ROH59_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806871.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDIDGVNLAELINMVCDNGYS
                     LRVVDESDRTSADCTPPFVALTGIRCSTAHITETDNAWLYSLSHQTSDFGESEWIHFT
                     GTGYLLRTDTWSYPVLRLKRLGLSKTFRRLVVTLIRCYGVSLIHLDASAGYLPGLPTF
                     DW"
     gene            complement(9414..9791)
                     /locus_tag="ROH59_004471"
     CDS             complement(9414..9791)
                     /locus_tag="ROH59_004471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDX4806872.1"
                     /translation="MKTLPDTHVREVSCCPSPVTIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDLPGFSACTHSQLINSIDILRARRATG
                     LMIRDNYRTVNNITLGKHPEAKR"
     gene            complement(9881..10249)
                     /locus_tag="ROH59_004472"
     CDS             complement(9881..10249)
                     /locus_tag="ROH59_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDX4806873.1"
                     /translation="MSDTLSGTTHPDDNDDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFRDADAYPLDQAFPLLMKQLKLMLTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPETKK"
     gene            complement(10412..10633)
                     /locus_tag="ROH59_004473"
     CDS             complement(10412..10633)
                     /locus_tag="ROH59_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDX4806874.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            complement(10696..11172)
                     /locus_tag="ROH59_004474"
     CDS             complement(10696..11172)
                     /locus_tag="ROH59_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HDX4806875.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEYGLL"
     gene            complement(11188..11661)
                     /locus_tag="ROH59_004475"
     CDS             complement(11188..11661)
                     /locus_tag="ROH59_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX4806876.1"
                     /translation="MKTLSQNTTSSACAPETDLQKLVATPVPDERRISFWPQHFGLIP
                     QWVTLEPRIFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRIID"
BASE COUNT         3450 a         2575 c         2501 g         3319 t
ORIGIN      
        1 gctcgatctt gggaaacgag ccaaagttcg ccaaattatt gaacatatgt ggtttcaacg
       61 taaggcatta ttaaacggtc gtaatggcaa cctatcgaat acagcctggg cagctttgca
      121 atcctataca gttcccgagt cgttaaccgt tgattataag aatcggcgtg agcctgccgt
      181 atttaacaaa acagataaca gcgaatggtt gctagttgat tcacagctcg agcaagtgga
      241 ggatttggta gagctctacg ccgaacttaa acgaggccct aaatctgccg aagccatcca
      301 gcgttttgcg gtggttacgt tccaccaatc ttacggctat gaagaattta ttgaaggtat
      361 acgcgctcgc tctgacgaga gtggcaatat ctcttatccc attgagccgg gtatctttat
      421 gcgcctttcc caacgtgcca atgccgatcc aggacatcgc tacgccattt tcattgatga
      481 gatcaatcgc ggtaacatat ccaagatctt tggtgaacta atctcactca ttgaagtaga
      541 caagcgtgca ggcatgccca atgcaatgag cctacaactg gcttatagcg gtgatcactt
      601 cagcgtaccc gccaatgtcg atatcatcgg agccatgaat acagcggacc gttctttagc
      661 tctgatggac acggctttgc gccgtcgctt tgactttgtc gaaatgatgc ccgatctctc
      721 tttactgagt ggagctaagg tgaaaggcat agagctcgag tcgttgttag agaaactcaa
      781 tagccgcatc gaggctcttt acgatcgtga acatacgctg gggcatgcgt tctttatgcc
      841 ggtaaaaaat gcactcgatg ccggtgatga agaagctgcg tttaaacaat tgaagatcgc
      901 attccagaaa aagatcattc cgcttttaca ggaatacttt ttcgatgact ggaacaagat
      961 ccggttggtg ctggcagaca atcaaaagca agacgacaac ctgcaattcg tgattgagaa
     1021 aaccgacgat ctcgatacgc tttttggtaa caaccatggt ttacgacacc atgatcagca
     1081 atcaacagct tacgaactca aagatttcga tcaagagatc tggaatattc cacaggctta
     1141 tcgttcaatt tatcagcccc agcagactcc ccttgatgag caggctgtaa atcatgggtg
     1201 aagttatctc cgtttttgaa tatgacctat tggggagtga caaagcggct tcagttggcg
     1261 caaaactggt gcctccactg gtctttaatt atttagaagc gcttagcttg gcaagtaatc
     1321 aagggagcca gttcctcaaa ctcacctctc gctcaggctt caaattgctt caggttcaaa
     1381 actacgcggg gatgctttca acacctcacg gtttccagct tgagatactg cccaaggttg
     1441 gtaaaaacct cacagcggct aatgcacgtc aaacattact gacgatgcta agccatttgc
     1501 ctgggtttcg acatattgaa actcagcaag ccactcttca ggctcagcgt atgcctttgc
     1561 ttgagatttt tattcaccag tttttgcata gcgttagcca attacttaaa caaggtttac
     1621 gctccgacta tgtgagcgag caaggtaatc tggcttttat gaagggcaag ctgatgcttt
     1681 ctgcacagct gcgacataac gcggtgaatc gccataagtt ttgtgtcgat tatgatgact
     1741 acatgcctga ttgtgcagcc aatcggctct tacactccgc gctagataag cttcttagtc
     1801 taaagctgtc atcagagaat caacgctggc tttacgaact gcgctttgcg tttgacggta
     1861 ttccacttag ccgggatatt gaacgtgata taaacaactt acgcctcgag cgtggtatgg
     1921 ctcattacaa cgagccaatg gcgtgggcgc aattgatcct gagaggaatg agtccgagtg
     1981 ctttgcaggg aaacaccaaa gcgatatcac ttttgttccc tatggaagcg gtatttgaat
     2041 cctttgtggc acagacccta ccctacgaat taccttctca tctcaaagta ataccacaag
     2101 cggctactta ttctcttgtg aagcacgggt ctaacgattg ctttaaactt cggccggatt
     2161 tgttgattca gtcacgtcga ccggtacaaa ccaaattggt gatggacaca aaatggaagc
     2221 taataaatag caactcccaa aaaacaacac agtatgggct agcgcaagcc gacttctatc
     2281 aaatgtttgc ctacggtcaa aaatacctaa atgggattgg cgaaatgtac ttaatctatc
     2341 ctgcgcatga tcaatttaac caaccgatac agcagcattt tgctttctct aaaacattaa
     2401 aactatgggt tgttccgtac cagataacag caaaccgcgg ggagaggatg atgtgggtga
     2461 aggatgtgtc cagtatataa atttctagcc aagctggcga tgaaccagtc ctctaaaaaa
     2521 tgggtataat catagtttat ttactaatta aattaatata aagtaattac tttattatat
     2581 ggagaattta tgaaaatggg aaaaattgca gttactccta ataatgataa agcagccagc
     2641 cactctaaag atgaaaattt agccacaaat acaattaaga aaaacgtaaa acctaaatat
     2701 ggcgatgcgg catttttaga gtacactcga ctaatagtta accacccgaa ttattttgga
     2761 atgccagatc cctttgggga aaaaggtgag attcaatggg aagctccatc aaatagggca
     2821 tcggggaaat ttaaacacac tcatcaacgg cgctatgaat ggtggaaaaa taaagccaga
     2881 agtattggga tagaccctga cactgaaaaa gcatggatta gtaaaacagc taaactaatt
     2941 catccacttg gagttaaacc atgcaagaaa tgcggtaaag aaatggaatt atcttactcc
     3001 tacccaaatg agcatttctt ttctcgggtt aggaaactta attatataga tgagactttt
     3061 gagctatctc aaaatgaaca catagttgat ttgttgactc gtttagatga tagatttggt
     3121 gaaagaatat atttagattt accacattta ttttctacaa aatccatcac gattccagat
     3181 atttcaagca atctcgaagc atggattgag tatctaaaag aacaatacat acctcaagaa
     3241 tcacgtatgc ttagccctgg agccatggca aatcctccag atcgttttga tggatttcat
     3301 tcatttaacc gctgttgtcg ctctattgct gataaaggaa ggaccaaaga aaatcttaaa
     3361 tcttatgtta ctgacagaag agttttcgaa tattgggtgg atggtgattg ggtagctgca
     3421 gacaggctaa tgggccaagt tagaacaaat aatatattta ttaacgagga atgtttgaat
     3481 gccggaaatg gtggtttaca tccaactcct tgccaagcag atcacattgg cccaatctca
     3541 ctagggtttt cccatcgccc acaatttcaa ctactttgca aatcatgtaa tagtgccaaa
     3601 aacaatcgta tgtatttaag tgatataatc tctttattag aagctgagaa tgaaggtcat
     3661 acggttattt catggttcgc agaagaagta tggaatcgac taaaacactc tgtagatgat
     3721 agtgaaaaag ccttaagact aagtaaaata ctacgtgata atagacatac atatatgaat
     3781 cttcttaaaa aaataatgga tgaaggttat tatactttcc ttgcaagtct tttacatctt
     3841 gaggtagcca attataaccc aatatttgag ggattatgca tttcaaatca tttaactcat
     3901 tataaatcat taaaaaaaat aaaacgtgaa tcaaaatatg ctgctgtgca aaaaacaaga
     3961 cgaatcagaa tagcatttac ttcattgaat gattatcata gaaaagaaaa tcggaacgca
     4021 tttattgtat caaatgaatt atctgagaag tttttctctg aagctatgga taatttaaaa
     4081 tcattaagtg aaattacatc ttgcttagat gaaaaaatat ccggaataat atctgagaat
     4141 tcagattcaa aaaatgaatt tcgaacaatc attacagatc tacgagaaat agtgacaaac
     4201 aataaagaaa aattcaactt gatattaaaa tatctaatat cagggatgag cgaaatagga
     4261 aaagaactgg aatcatattg ggaaaatgat cgttatgttc gctcaatccc agaagaattt
     4321 atagagtaag acatagccct cttataaaga gggctttata ttcctttcat aatattctga
     4381 aggagtaata ttacctctca tgaataattg atagtcattt tcggggtgat ggatataata
     4441 tttaccactt ccatcttcac catgttgcaa aggaggcaga tcagataatg catcctttac
     4501 agatacccaa gattccttat cttctgttaa tttttgtgga ggttcaattg aaaataaagg
     4561 gtcgtttgaa ccaaccaata taaccctttt tcggcgctga gggattgcat aatgttcaga
     4621 gtttaatatc catccattca tagttttcat ggttgatgag aattcttctt tgactctttc
     4681 aaagacctta cctttttcca tattcaacaa accagcaaca ttttcaaaaa taaaaccgtt
     4741 tggttttatc tcatttaaga gagatttata atgcataaaa agtgaatttc ttggatcatc
     4801 cattgttctg gcatttcctg ccgtagaaaa tccctggcat gggggtccac caagtatcca
     4861 taattgttta tcaaaatata atttcttaaa tcctgatatt ttatctgcta tttttgaaaa
     4921 agtttcatta tcagaaatgc tgccacataa aacttctttg tgaacattgt ttgaatatgt
     4981 ttgtagatat ttttcttcaa tatcattcgc caataatgga gtccatccag cccatttgaa
     5041 tcctagtccc agccctccag ctccggaaaa taaatcgata taataaccag tattacctat
     5101 cgccttctct atttctttcg caatcagaaa agctaaaaat gggggcactg cattaccgat
     5161 ttgggtatta attgctgttt gacctccgaa gaaaataaaa tcatccggga acgattgtag
     5221 tcttgcagct tctctctggg atagaacacg atcttgctca tagtgaatat ggcaaccatt
     5281 cccaggtcgg ttaaaatatg tattgatagt atatgcaggc atatctggaa gtaatctacc
     5341 gtagtatgtt gaacggcttc cttttccttg tgcataacta tccctaattt gctctattct
     5401 tttagacggt acatctaaag gaatattttt ccagttgcca cctggcggta ctgagttaac
     5461 aatcatcata tccaattcac ttagctttgc tgccttgtga ttgggaatca taaatgtttc
     5521 acttttagtc ataatgttga aaaatcctca ataaactttc tttttcagct aactcaatct
     5581 tatcaaatga agacagaagc ttattaaatt cattcaaatc caatttgtaa atatttttgg
     5641 caacataagc ctcaattttc aactcagcat cacaacatcc ctctatgcaa gaaatcacaa
     5701 gttgttttaa ttcagaatgt tgtaataata ttttttcaga cggtattgca gtttttcgta
     5761 aggctgacaa tgatacatga ccagtagcta aaaagcttct taattgaaat tcaaaacaaa
     5821 gggagtttat aataccaagc aaactaaaga gcgaatcttg cgaaccactt ttataataga
     5881 ccacccctaa tgaattccct gccaaagagt taggaggtat tatcgttgca atcattcgcc
     5941 ttttttgact cgggcgtgaa atgtcacgcc atgcaatcct tacgaaatta gaattggata
     6001 gaaccttatc aatttttttc gttattctta agctcttctc attatgaaaa ttatacctcc
     6061 caatcatttt tcctttaatg aataataatc cgccgccact tttttgtgtc cagtcactac
     6121 taccagtttc atctatttct cttcctgccc atatctctcc atttttttcc agactacccc
     6181 atgttgggta tccctcttgc agctttctta acaaatgaac ggcatgaaca ccttgagata
     6241 ccggaatgct aagatattga gaatctatac tagacaaatc aaaaaaacct agtgatttaa
     6301 tatttaagtt tttatcatac acactaagtt gaatattatc attaagggat tcacctttat
     6361 taaaaataaa agaacatgaa gaaacatcag caccgccgaa taatttagcc tcagctggat
     6421 aataatttat gcaatcaatc ctccctgaat taaaaaactt ttcacgtaat atgtacgatt
     6481 gttcatctgc gaaaaaagat gcaggcataa ctatagctac caatccattt ttattacata
     6541 tttctaagct aagttctgca ccaacacgtg aaagattagt cccccaccca gcaaatttac
     6601 gcttcggctg agaatatggc aatactcttg acaaataatc atcaaactca cgaagagagt
     6661 ctatatacat cgatttcata gatggttcaa aaaaatcgag ctctctagaa tctggtttta
     6721 tattctccca aggcggattg gttataacac aatcaaaata atcaacatat tttttaaatt
     6781 cataaaaaac atcactattt tttatagtaa tgttaatatt tgcacctgct aacttaagtt
     6841 cagacaacgc atttttagca taagtgaggc ctgtattttc tatatcgaac agataaacat
     6901 tccactctac atctggaaaa ccatttatca tccattgttt aataagcaat gtaataagtc
     6961 gaccatcccc tgaaaatgga tctgcgacat tataactttt tttatcacag gaatttatca
     7021 atggtaataa cttctctatc atcaaaagag ctatttttgg atctgtatag tatttacctg
     7081 tcgctttttt agtgaatttt gttgtctcgt ccaaggacag tgaattaatt aaatggatat
     7141 gtttcatgta aaatatctct tccattaata atatggatta tatcatttaa cttgtgaaca
     7201 ctcaacaata actgtacata aaaacagtca ttaaagattt cccctagagt gagcatcgct
     7261 ataaaaattt aaattaattt tatcctgctc cgaaagaaac agttatcatt tattccataa
     7321 agaataactt gctttataat cactttaaat atcgatatca attttaatac tatggttact
     7381 taccatatca ataaatagct taacccgtta tctcgatacc ccttaagaac cccttccgca
     7441 actgcaacat aatctacgct catccacatg cctggtgcgt attaccgtga aggagatcgg
     7501 tgagttattg agtgatctcc tttcatgaaa atacgcacct ggctttaact gttcctgata
     7561 taagttgaca gttttctgtc cgtaaaacgg ttgatgaact tcatcgggcg ttttgtattt
     7621 caatgccaaa tgtgaccgct catggttata aattgccacg aattctttta ccatttaccg
     7681 gccctacgtc agctctgcag gacgcgagag taaaaactca ttttcaggat tccgtttatc
     7741 cactcagcct gcgcattctg gtggcagtta taaccattag tcattgaaca ggttattgat
     7801 aaataattaa aaaactcagt tttctggctc gcctgctcaa gctgttcttc aagttccctg
     7861 attctttgct cgggtgtcag cgggacagtc gccagagcca caggcagtct cctctttacc
     7921 tggtcaggaa gtccggggct ccagtcaagc cggccatatt tacgcaacca gacaagaacg
     7981 gtggagcgcc cctgaatgcc ataactgcag ccggcctgtt tataagtcat ctcgcctttt
     8041 tcaaccttct caacaacggc tattttaaag gatagaggat aatcacgttg agtgcgtttg
     8101 aacccagaca tcatcacgtt ctccgggttt aagtcaggaa cgtgtcatag ctattcagga
     8161 cgggtcaccg acacaaaaaa agtcgccctt gagcgactcg atttgcatac ggtatggtgc
     8221 gaaggccgga ctcaaacatg cgatttaacc tcatgattta aaattgttaa taataaacaa
     8281 caccatccta taccaacaca gataccaaca cgaaaaatca ctggttttcg gcatcgaacc
     8341 aggacaatca ggtcctgatt gagataccga gctctgttac tcgtcatctt cctcgacagg
     8401 ctccattgca tcaagtggta ctcgcaccat cgcgatagaa ccaatccgga taaaagcatc
     8461 ttccccatct atatcggtta actgatatcg cttacttgat gccggataat tgtgtcgatt
     8521 ggcaacagtg tactctttcg tacagccaga atgtggcaga ctgaggtgga atagataacg
     8581 tccgtatgcc cgctgaccac ctccgggcgg gagagtgtgg tatctgacat catcattttt
     8641 cctttctgtt tataaatgaa aatgccagcc gtgttcaggc tgacgtcagg gaagtgaaat
     8701 cgggtgagtg atcttcactg gttctggtac aaaagttact gttggcgcag ggtacggata
     8761 ccctccctgg cctgtgcgat acagggcaac agtgctgccg aatctgtttt atcctcatcg
     8821 ttgtcgaaga taattcccga ttcgcagtcg atattgtcct gcagccacgt aatcagaata
     8881 tccagcgctg tttccgtggt taatgatttc atgttgtgaa tttccggatt accagtcgaa
     8941 agtgggtaaa cccggcagat atccggcact ggcatccaga tgaatgagac tgacaccata
     9001 acaccggatg agtgtgacga ccagacgacg gaacgttttt gacagcccca ggcgcttaag
     9061 ccgcagaacc gggtatgacc acgtatcggt acgtaacaga taaccggtac cggtaaaatg
     9121 aatccattct gattcaccga agtcactggt ctggtgtgac agcgagtaca gccaggcgtt
     9181 gtccgtttcc gtgatatgtg cggtactgca gcgtatgccg gtaagggcaa caaatggtgg
     9241 cgtgcagtct gctgaggtcc ggtcagattc atcaacaaca cgaagggagt agccgttatc
     9301 gcagaccatg ttaatcagtt cagcgagatt aacaccatca atgtcaacga caatgcgccc
     9361 catgttcagc gcctgcacgt taacgctgtc ggcttccagc gtcagggcca gtttcatcgt
     9421 ttcgcctccg gatgcttccc cagggtaatg ttatttaccg ttctgtaatt gtcgcggatc
     9481 atcaggcctg ttgcccggcg agcccggagg atatcgatgc tgtttattaa ctgagagtgg
     9541 gtacaggcgc tgaatcccgg caggtcggta cgtaccagtg cgtatttttc cacgagaaag
     9601 ttcactgcat cacacagtga aatgcctgcc tcaatatgct gctcaatcac acgttcatca
     9661 gcgaacggtg tgtcattcag cgtaaggccg tagtgctggt ccagcagtcg ggtgagcagt
     9721 gtctgccaga tggtgactgg agacgggcag cacgatacct cccgtacatg cgtgtcgggt
     9781 aatgttttca tactgaagat tttcctgata tgcagagata aaaaatggga cagtggcgtg
     9841 gtgaaaacac caggccggag cagaaggtta ttctggtggt ttactttttc gtttcaggtg
     9901 tcggataaac agccagataa acgtaaccac aggagccgag ggtgtcggct tcacaggtca
     9961 gccccttcgc atacagtgtc acggtatgct gatggcgggg attcagttca ccactggtga
    10021 gcattaattt cagttgtttc atcagcagcg gaaaggcctg gtccagaggg tacgcatccg
    10081 catctctgaa ccggcctctg ataccggcac ggtcggcaag gtaatgcaac cggttaccct
    10141 cctgcaccag acgggcgccg aaacagggcg tcactgtgca gggtagtccc caccagggat
    10201 ggtcgtcatt gtcatcggga tgcgttgtcc cggaaagtgt gtctgacacg ataaaatcct
    10261 cacagaaaat cggtgaatga tagtttaacg atgacgggtc agccggcgcg cagaccggct
    10321 tcggtaaagg tgtattcgtt gatgagcagg acctcatcca cagcggcgtc tgagctctgc
    10381 cagtcgtact cgttttccgg gtgacggaac atcagttcag ggtgacgctc atcagccgga
    10441 catacggacc aaaactgtcc ttacggcgtt ctgcaaacac ggccagcaca ccgggaatat
    10501 cctgcacttc acgaccggta tacgcttcag cactgccgtg ccagcggtat ttgccggtac
    10561 agaacggaaa aagacgggat gccggatgct gacggtgaat acgcatggct tcgccacggg
    10621 tgatgatttt catagtggga tacctctgaa gacagaagat aaaagtgaaa acaggtgtga
    10681 tgtggttgtg acgggttaaa gcagaccata ttcggcaaag gagaaaacct ggctgccacc
    10741 gactatcaga tggtccggca cccggatatc caccaggccc agtgcctgta ccagacgttc
    10801 cgtgataagg cggtctgcct tgctgggtgt gacttcaccg gacgggtgat tgtgtgccag
    10861 caccacagca gcggcattgt gatacagggc gcgtttaatc acttcccggg gatggacttc
    10921 cgtgcggttg atggtgccgg tgaagagggt ttcaccggca atcagctgat tctggttgtt
    10981 cagatacagc acccggaact cttcacgctc cagtcccgcc atgttcagaa tcagccattc
    11041 tcgtgccgca cgggtggagg tgaaggccac gccgggttca tgaagatggc ggtccagggt
    11101 tttcagggcc cgttgaatga ggctgcgctc gccgggcgtc atctctccgg gcagaaagga
    11161 aagctgttgc attgtacttc tctccattca gtcgatgatg cgcataatgg cgctgcattc
    11221 cggatgctgc agggcgtaat cccgcagccg gtaataatgg accgtcatgg cataacactc
    11281 cgtacgacag gcatgatgac tgtacgtcat cagacaggca gcaatgccgg cggcttccgg
    11341 gctcatttca gcgcggttac cgttcatggc attgaacagt acccatgttt cgtcatcatc
    11401 gtcatccggt tcgggtgcca taaatgcccc gccgttgttc agggtgtaca gattccagat
    11461 accaccgcag tagtcttcac acagacggtc catccagccg aagatacggg gctccagggt
    11521 cacccactgt ggaatgaggc caaagtgctg cggccagaag ctgatgcgcc gttcatcagg
    11581 gacgggagtg gctaccagtt tttgcaggtc agtctccggt gcacaggccg aagaggtggt
    11641 gttctgagac aatgttttca tgtatgaaat ccttgtaatg tgaataaatg agagggagta
    11701 aaggtcggga gctggcaaca tcacgttcat cactgaccgt gatgacccgg taatatcagg
    11761 gatgaatgat attcggctga aattccggac agccgtacgc gtaaccgttc cggtcacaga
    11821 cggatggcca gatgccattg cctgt
//
LOCUS       DAPOXO010000121        11791 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPOXO010000121 DAPOXO010000000
VERSION     DAPOXO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11791
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.121"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(1..298)
                     /locus_tag="ROH59_004476"
                     /pseudo
     CDS             complement(1..298)
                     /locus_tag="ROH59_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="involved in the synthesis of a cofactor required
                     for carnitine dehydratase and carnitine racemase
                     activities; frameshifted; incomplete; partial in the
                     middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
     gene            306..548
                     /locus_tag="ROH59_004477"
                     /pseudo
     CDS             306..548
                     /locus_tag="ROH59_004477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067515.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(720..1046)
                     /locus_tag="ROH59_004478"
     CDS             complement(720..1046)
                     /locus_tag="ROH59_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HDX4806877.1"
                     /translation="MKRTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVAL
                     KTDAETEKLVTDINAERKASYQQLAKQNNVSVDDIAKLAGQKLVERAKPGEYVQGING
                     KWVRKF"
     gene            complement(1054..1239)
                     /locus_tag="ROH59_004479"
     CDS             complement(1054..1239)
                     /locus_tag="ROH59_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HDX4806878.1"
                     /translation="MKILLAALTSSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            complement(1236..3875)
                     /locus_tag="ROH59_004480"
     CDS             complement(1236..3875)
                     /locus_tag="ROH59_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HDX4806879.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKL
                     PQTEQSPAAPKTLAQWQAMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFTMPLVPDGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTG
                     EAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPVVWGRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLAPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEDKQ"
     gene            4083..5072
                     /gene="ldhA"
                     /locus_tag="ROH59_004481"
     CDS             4083..5072
                     /gene="ldhA"
                     /locus_tag="ROH59_004481"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDX4806880.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
                     RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEA
                     AFDQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            5183..5605
                     /gene="hslJ"
                     /locus_tag="ROH59_004482"
     CDS             5183..5605
                     /gene="hslJ"
                     /locus_tag="ROH59_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HDX4806881.1"
                     /translation="MKKVAALVALSLLMAGCVSSDKIAVTPEQLQHHRFVLESVNGKP
                     VTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(5602..5868)
                     /locus_tag="ROH59_004483"
     CDS             complement(5602..5868)
                     /locus_tag="ROH59_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HDX4806882.1"
                     /translation="MRAAFWVGCAALLLSACSREPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            6142..9666
                     /gene="nifJ"
                     /locus_tag="ROH59_004484"
     CDS             6142..9666
                     /gene="nifJ"
                     /locus_tag="ROH59_004484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDX4806883.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISHIATLKSR
                     VPFIHFFDGFRTSHEINKIVPLADDTILELMPQAEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEQAMNDFAAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTSEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRNVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARF
                     TVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSAAEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPTELLT
                     ALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSEALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
     gene            10032..11165
                     /gene="ompN"
                     /locus_tag="ROH59_004485"
     CDS             10032..11165
                     /gene="ompN"
                     /locus_tag="ROH59_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HDX4806884.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSTNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADVGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            11306..11740
                     /gene="uspF"
                     /locus_tag="ROH59_004486"
     CDS             11306..11740
                     /gene="uspF"
                     /locus_tag="ROH59_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HDX4806885.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEAEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEL
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
BASE COUNT         2992 a         3003 c         2842 g         2954 t
ORIGIN      
        1 accaggcgtt tcctgccagg ttcaacttcc cgcaatggct cgacttgatg caacgtctgc
       61 ttacaacgag tcaccagcac ctgatgccct gctttctcaa tgccagctcc tgctcgctga
      121 gttcacgaat cgctttcgcc gggctgctga caatcaagta attagtcggc atttctgctt
      181 tggctttcac aaatgcggaa acaccaacaa tactgttctc accaatcacc acaccgtcca
      241 tcactaccgc gttaattccc actaatgtat ggcggtggtt aatgcagccg tgaagaatag
      301 tcggagatac aggtatgtca gtacgtagtt tgtaccgaat gtttgccgat aaaggtttgg
      361 tggtcgcgca atatattcgt aaccgtcgtc tcgatttttg tgcagatgcg attcgccatg
      421 ccgcagatga tgaaaaactg gcaggcattg gctttcattg gggattttcc gaccagagtc
      481 atttttcaac ggtatttaaa caacgctttg ggatgacgcc aggcgagaat cggcgtaaat
      541 tccgctaact aattcgcgtt gcatgtacag caacgcgaat tagttaaaac agatatttga
      601 ctatgcattt ttcagggcga aaggcaattt gacaggcgtt tttgaataat catcttgttt
      661 ccggaaaata gattaatcgc cttctcctgt agcgttatcc cgatattgcg gctttactat
      721 taaaattttc gcacccattt accgtttatc ccttgtacat attccccggg tttggcccgt
      781 tctacgagct tttgcccggc gagtttcgcg atatcatcta ccgacacatt attttgcttt
      841 gccagttgtt gatagctcgc tttacgttcg gcattaatgt cggttactaa tttctcagtt
      901 tcagcatctg ttttcagcgc aaccagataa ccataaaatg tttcgcctac ccgcccctga
      961 gttctggctt catccagagt caatgccatt acattgctgc ttaccaagcc aacaagaaat
     1021 gcacaaagaa gtaatgttct tttcatcatc acctcaaaaa agatcgctac gggtctcaag
     1081 cagctcttcg acatctttgt ctgccttgat gatgatctca tgctcaattt taacgttcat
     1141 attgatagtg atcggttcct taggtgcagc gacttcaata cgaggcgtac agccaaccag
     1201 cataaaagat gacgtcaacg cagccagtaa aattttcatt gtttatcctc acactctttt
     1261 ccttgcggac agtcatttcc cggcagacgc gcgttctgct ccagccatgc ctggagatta
     1321 tcgccaaagc gtaaactgcg ccacagcgta aaaatattct cttcatgatg gtaattaaga
     1381 tttaccgtac cgcttttacc atcaacgcga ctggtacctg taatattggc ctgcatggtt
     1441 aataaaccga gattatctaa attaattttt gtcgatgaac ggctaatttc catatagcgc
     1501 aaccagttaa ttgctgaacc cgcggtcata ttgtctttca ccaccgcatc tgcggtgtct
     1561 ttatccagcc gcaaggtcat tggtccgcta tttgccagcc agccgtcttt cactatccat
     1621 ttttcattgt ttaaccataa cggcagtgca ccactaaatg ccccggacat ggcgaattgt
     1681 ttcggattaa cggcgctaac cagttcgctg gatgagagat tattcagtcg caacagtgcc
     1741 gggtcatgtt gcggcatacg taattgtttc atcagcacgt taccgcctaa cacatcgaca
     1801 ctaacatcag tcaacagcaa tggttcttct tcagtccacg gataacgccc ttgcaaatca
     1861 gccgtaatat ttttcgctgt caccagatta atcacttcgg caattcgcaa cgtaacgggg
     1921 ccgcgagtcc ccagatgcca ggctccatcg gcaaaacgga aaggcaggac aaaatcgaca
     1981 ccgttaacct gattatctgg catccaggca ctaccgcctt tcaatacgcc gtgccccccc
     2041 gcgcggaatc cttgttcggg cgctgctgaa aatgcgacct gagcatacag ttcaccatcg
     2101 cgtaagttca tcttccagtc gggtggcgcc aacggctgga atacagtcag tgattgttta
     2161 ggccaccagg cgttaccgcg cagacgaata ccgtcccagc gaccatttac ccgaaccggg
     2221 ccaatctcac cagcatgtaa atcgccttta aagaggaaat acgtcggatc gcgcccatcg
     2281 acactaaatt ttaaggttga tggcggtaac acactgccgc cagtgaacag cgtttgcccg
     2341 gcgtccagtg acagagcgcc gctgaaggag ggatgctgtg cgtcacgtcc ccagacgacg
     2401 ggcttgtcga gaattaatcg cggcttttct accgtcatcg taccgtattg taactggtcg
     2461 aaaccggtgg agagatcggt cagcgtaatc gtgctgtcat gccactcacc ttttcctgcg
     2521 acatcccagg tggcattcat cggtgtaaaa ctcccttttc cccagtagcg ccactgccag
     2581 cggccagcgt cagggagaaa atcattcgcc agcccatcca tatgcagcac gaaatcgccc
     2641 agttcatttt catgcgcctg caaaatggcc tgcaaacgtc cgtcaacacc acgttgggtg
     2701 acttttacac ccgctaaagg ccagcggatt tcatcgatgt ccagcgaatc aatgactctt
     2761 ccctttgaac gaagtaacgc gccaggctca aaggtcagcg ttgggtcaga cagacttcca
     2821 cttagctgcg caggtaaacg ggcatataaa atgaggtccg cctgtttcgc ttcaccggtc
     2881 agctgcagag gcagctggct gttatccatg cttaattttc ctgggccaaa atttaacacc
     2941 gcgttgcctt tacccgcttg cccctgggtc agcacactca gtcgcccgct gaccagagcg
     3001 ttctcgagcc ctgcctgcca gttgtcgact ttgacaccca gtcggccact caaaggaaaa
     3061 cctgcatacg gccagctcca gcgaccatcg cttacggtca attgttgacg agtaatttgc
     3121 cacggcaaat cgagcaacgg atcgccgtta tcccgtgcca gcacaatcaa ttgcccgcta
     3181 ttttcctgcc agtccagctc ggcatccacc agtgaaggct cctgcggtaa gtttaacgtc
     3241 gcagtagcat gaccacttac aggaagtcca tccggcacga gcggcatagt aaattccccc
     3301 accagtttta ccggcggctg attttcaaac gcgacgacat ccagttcgct gactgtaagt
     3361 tgttgccctt taagctggcc ttgaaattta actttttcgc cctgataacg cagttgctgg
     3421 atatcggagg ttaatgcgag agagagtttt ccctgccatt cctgccaggg agaaaaaatc
     3481 agtttatcga tattgatcca ggtgttaggc aacatggcct gccactgcgc gagggttttg
     3541 ggagcggctg gcgattgctc cgtctgcggc aatttcgcca gacaagcaga atcaagttct
     3601 accgtgccga cgttcaataa ccagcggctg ggatgtgaaa ggctggcgtt ggtgatatgc
     3661 gcaagctgac aatctcccac cagataacgg agatcgggga tgattaaacc tttacgcgta
     3721 atgcgtgggc tttcatctaa tgcaatacgt gtcccgagcg gtagccagat gcccgccagc
     3781 gtgggaaccc acagcccgag cgtcatcagc agcgtcaacg gcacaagaat aatcagtaat
     3841 aacagcgcga gaacggcttt atatttaccc agcatgggta gttaatatcc tgatttagcg
     3901 aaaaattaag cattcaatac gggtattgtg gcatgtttaa ccgttcagtt gaaggttgca
     3961 cctacactaa gcatagttgt tgatgaattt ttcaatatcg ccataacttt caattatatt
     4021 tgaaattttg taaaatattt ttagtagctt aaatgtgatt caacatcact ggagaaagtc
     4081 ttatgaaact cgccgtttat agcacaaaac agtacgacaa gaagtacctg caacaggtga
     4141 acgagtcctt tggctttgag ctggaatttt ttgactttct gctgacggaa aaaaccgcta
     4201 aaactgccaa tggctgcgaa gcggtatgta ttttcgtaaa cgatgacggc agccgcccgg
     4261 tgctggaaga gctgaaaaag cacggcgtta aatatatcgc cctgcgctgt gccggtttca
     4321 ataacgtcga ccttgacgcg gcaaaagaac tggggctcaa agtagtccgt gttccagcct
     4381 atgatccaga ggccgtagct gaacacgcca tcggtatgat gatgacgctg aaccgccgta
     4441 ttcaccgcgc gtatcagcgt acccgtgacg ctaacttctc tctggaaggt ctgaccggct
     4501 ttactatgta tggcaaaacg gcaggcgtga tcggtaccgg taaaatcggt gtggcgatgc
     4561 tgcgcattct gaaaggtttt ggtatgcgtc tgctggcgtt cgatccgtat ccaagtgcgg
     4621 cggcgctgga actcggtgtg gagtatgtcg atctgccaac cctgttctct gaatcagacg
     4681 ttatctctct gcactgcccg ctgacaccgg aaaactacca tctgttgaac gaagccgcct
     4741 tcgatcagat gaaaaatggc gtgatgatcg tcaataccag tcgcggtgca ttgattgatt
     4801 ctcaggcggc aattgaagcg ctgaaaaatc agaaaattgg ttcgttgggt atggacgtgt
     4861 atgagaacga acgcgatctg ttctttgaag ataaatccaa cgacgtgatc caggatgacg
     4921 tattccgtcg cttgtctgcc tgccacaacg tgctgtttac cgggcaccag gcattcctga
     4981 cagcagaagc tctgaccagt atttctcaga ctacgctgca aaacttaagc aatctggaaa
     5041 aaggcgaaac ctgcccgaac gaactggttt aatcttgccg ctcccctgca ttccagggga
     5101 gcttattcag ataatcccca aagacctttc atcctctatt cttaaaatag tcctgaatca
     5161 gaaacagtaa ttgagaacca caatgaagaa agtagccgcg cttgttgcgc taagcctgct
     5221 gatggcggga tgtgtaagta gtgacaaaat tgctgtaacg ccagaacagc tacagcatca
     5281 tcgctttgtg ctggaaagcg taaacggtaa gcccgtgacc agcgataaaa atccgccaga
     5341 aatcagcttt ggtgaaaaga tgatgatttc cggcagcatg tgtaaccgct ttagcggtga
     5401 aggcaaactg tctaatggtg aactgaccgc caaagggctg gcaatgaccc gtatgatgtg
     5461 cgctaacccg cagcttaatg aactcgataa caccattagc gaaatgctga aagaaggtgc
     5521 acaagtggat ctgaccgcga accagttaac gctggcgacc gcgaaacaga cattaactta
     5581 taagctggcg gatttaatga attaatagct gccacagctc ccggcggcaa gtgactgttc
     5641 gctacagcgt ttgccgttgg gtaatgcaca catcccaatc gccgtaccat ccagttgacg
     5701 ggcaacagaa agcgaaccgc cgatcattgc acaatttgct tctccactac tggacatcga
     5761 cgcttttaaa cctggcgcta cgtgcgccgc agtcgcctgc tgaacaggtt cacgactaca
     5821 cgccgacaac aataaagcgg cacaccctac ccaaaacgct gctcgcatct tttcttcctc
     5881 tgatcttcaa gccaaacgac accgccataa ataataggca gcacagaggg cggcgtcgag
     5941 agctgtcctg cgcgttgccc cgcattttta cttttttatg gctatttttt tgccctctgt
     6001 ttgatcaaaa cattcattac gctgatgtgg gggacacaaa agcgaaaatg cagaagaaag
     6061 ccatttgcta aaattgaacg attactactg ggcgcgcagc aatttcgtgc gcccctcatt
     6121 tgcgcaatgt aagggtgtca tatgattact attgacggta atggcgcggt tgcttcggtg
     6181 gcgtttcgca ccagtgaagt tatcgccatc taccctatta cccccagttc cacgatggca
     6241 gaacaggctg atgcatgggc cggaaacggc ttgaaaaacg tttggggaga cacaccacgc
     6301 gtggttgaaa tgcagtcgga agcgggtgct atcgctaccg tgcatggtgc tttgcaaact
     6361 ggtgccctct caacatcgtt tacgtcatcg cagggtttgc tgctgatgat cccaacgctg
     6421 tacaaactgg caggcgaact cacaccgttt gtcctgcatg ttgcggcacg taccgttgcc
     6481 acacatgcac tctctatttt tggcgatcat tccgacgtta tggcagtgcg ccaaacgggt
     6541 tgcgcgatgt tgtgtgcagc aaacgtccag gaagcgcaag actttgctct catttcgcac
     6601 attgcgacgc tgaaaagtcg cgtgccattt attcatttct ttgatggttt ccgcacatct
     6661 cacgaaatca ataaaattgt cccgctggcc gatgacacga ttcttgaact gatgccgcag
     6721 gcagaaattg atgctcatcg cgcccgggca ctcaacccgg aacatccggt gatccgcggt
     6781 acgtccgcca atcctgacac ttatttccag tctcgcgaag ccaccaaccc atggtacaac
     6841 gcggtctatg accatgttga acaggcgatg aatgatttcg ctgccgcgac aggtcgtcag
     6901 tatcagccgt ttgagtatta cgggcatccg caagcggaac gggtgattat cctgatgggc
     6961 tctgccattg gcaccagtga agaagtggtt gatgaattgc tgacccgtgg cgaaaaagtc
     7021 ggcgtgctga aagttcgcct gtaccgcccc ttctccgcca aacacttgct gcaagctctg
     7081 ccgggatccg tgcgcaacgt ggcggtactg gacagaacca aagaacccgg tgcccaggca
     7141 gaaccgctct atctggatgt gatgactgca ctggcagaag cctttaataa tggcgagcgc
     7201 gaaaccctgc cccgtgtcat tggtgggcgc tatggtcttt catccaaaga atttggcccg
     7261 gactgtgtac tggcggtatt tgccgagctc aacgcggcta aaccgaaagc gcgctttacg
     7321 gttggtattt acgatgatgt aaccaatctg tcactgccgt tgccggaaaa caccctacca
     7381 aactcggcga aactggaagc cttgttttat ggccttggta gtgatggcag cgtttccgcg
     7441 accaaaaaca atatcaagat tatcggaaat tccacgccgt ggtacgcaca gggctatttt
     7501 gtttacgact ccaaaaaggc gggcggcctg acggtttctc accttcgcgt gagcgaacag
     7561 ccgattcgtt ccgcttatct catttcccag gctgattttg ttggctgcca ccagttgcag
     7621 tttatcgata aatatcagat ggctgagcgt ttaaaacctg gcggcatttt cctgctcaac
     7681 acgccgtaca gcgcagctga agtgtggtcg cgcttgccgc aggaagttca ggccgtgcta
     7741 aaccagaaaa aagcgcgctt ctatgtgatt aacgcggcga aaatcgcccg cgaatgtggc
     7801 ctggcggccc gtattaatac cgtcatgcag atggcttttt tccatctgac gcagattctg
     7861 cctggcgata gtgccctcgc agaattgcag ggtgcgattg ccaaaagtta cagtagcaaa
     7921 ggccaggatc tggtggaacg caactggcag gctctggcgc tggcacgtga atccgtagaa
     7981 gaagttccac tgcagccagt taatccgcat agcgccaatc gaccgccggt ggtttccgat
     8041 gccgctcctg atttcgtgaa aaccgtaacc gctgcgatgc tcgccgggct tggcgacgcc
     8101 ctccccgttt cggcgctgcc gccagacggc acctggccga tgggcaccac gcgctgggaa
     8161 aaacgcaata tcgccgaaga gatccccatc tggaaagagg aactctgtac ccaatgtaac
     8221 cactgtgtcg ccgcttgccc acactcagct attcgcgcaa aagtggtacc gcctgaagcg
     8281 atggaaaacg cccctgccag cctgcattcg ctggatgtga aatcgcgtga tatgcgcggg
     8341 cagaaatatg tcttgcaggt ggctccggaa gattgcaccg gttgtaacct gtgcgtcgaa
     8401 gtttgcccgg cgaaagaccg tcagaatcca gagattaaag ccatcaatat gatgtcgcgc
     8461 ctggaacatg tcgaagaaga gaaaatcaat tacgatttct tcctcaacct gccagaaatc
     8521 gatcgtagca aactggaacg tattgatatt cgtacatcgc agctaatcac gccgctgttt
     8581 gaatattccg gtgcttgctc cggttgtggc gagacgccgt atattaaatt gctgactcag
     8641 ctctatggcg accggatgtt gatcgctaat gccactggct gttcttcaat atacggcggt
     8701 aacctgcctt caacaccata taccaccgat gccaacggtc gtggaccggc atgggcgaac
     8761 tcgctgtttg aagataacgc cgaatttggc cttggtttcc gcctgacggt cgatcaacac
     8821 cgtgtccgcg tgctgcgtct gctcgatcaa tttgccgata aaatcccgac ggaattactg
     8881 actgcgttga aatcagacgc cacgccagag gttcgtcgtg aacaggtagc agctttacgc
     8941 cagcaactca acgatgttgc cgaagcacat gaactgctgc gtgacgcaga tgcactggtg
     9001 gaaaaatcaa tctggctgat tggtggcgat ggctgggctt acgatatcgg ctttggcggt
     9061 ctggatcatg tattgagttt gacggaaaac gtcaacattc tggtgctgga tacgcaatgc
     9121 tattccaaca ccggaggtca ggcatcgaaa gcgacaccgc tgggtgcagt aactaagttt
     9181 ggcgagcatg gcaaacgtaa agcgcgtaaa gatcttggcg tcagtatgat gatgtacggt
     9241 catgtttatg tggcgcagat ttctctcggc gcgcagctga accagacggt gaaagcgatt
     9301 caggaagcgg aagcgtatcc ggggccatcg ctgatcatcg cttatagccc gtgtgaagag
     9361 catggttacg atctggcact cagccacgat cagatgcgcc aactcactgc taccggcttc
     9421 tggccgttat atcgcttcga tcctcgtcgt gccgatgaag gcaaactgcc gctggcgctg
     9481 gattcacgcc cgccgtcaga agcacttgaa gaaacgttac ttcacgagca gcgtttccgt
     9541 cgtctgaatt cgcagcagcc agaagtggca gaacagttat ggaaagatgc tgcagctgat
     9601 ttgcaaaaac gctatgactt cctggcacaa atggccggaa aagcggaaaa aagcaacacc
     9661 gattaaatgc tctggataag gattatccaa ttcaaaaaaa aagcccggac gactgttcgg
     9721 gcttgtcttc ttatgtgttg gaaaatcagt agcaatgcaa tggcccaaca gaaaataaaa
     9781 tctgtgacaa taaaggcata taacccgcgc agaataacgt atagaaaatt aaaagtataa
     9841 tttttatttt gtatgtgtta tctccaatac attcaccaga cttattatca tttcagaaga
     9901 attatttaat taaggtttta cttaaggcgt aacaaatgat atttatcggc taactgaact
     9961 tctcctttag gatgttttca ctccccgaaa tggggatgaa aggcaaataa aataactaaa
    10021 ggatttattc aatgaaaagc aaagtactgg cactcttaat tcctgccctg ctcgctgcag
    10081 gtgctgcaca tgcagccgaa gtttataata aagacggcaa caaattggat ctgtatggca
    10141 aagttgatgg cctgcattat ttttctgata attcagcgaa agatggcgac cagagctatg
    10201 ctcgtctggg ttttaaaggc gaaacccaaa ttaacgatca actcactggc tacggtcaat
    10261 gggaatacaa tattcaggca aacaacaccg aatcttcaac aaaccagtca tggacccgtc
    10321 tggcatttgc cggactgaaa tttgcagatt acggttcttt cgattacgga cgtaattatg
    10381 gcgtaatgta cgacatcgaa ggctggactg atatgctacc tgaatttggc ggtgactctt
    10441 ataccaatgc agacaacttt atgactggtc gtgccaatgg cgtcgcgact tatcgtaata
    10501 ctgatttctt cggtctggta aatggtctga acttcgcggt gcagtatcaa ggtaacaacg
    10561 aaggtgccag taatggtcag gaaggcacca acaacggacg tgatgttcgc catgaaaacg
    10621 gtgacggctg gggtctttcc acaacatatg atttaggcat gggctttagc gctggtgcgg
    10681 catacacctc ttctgaccgc accaatgacc aggttaacca tactgcggcg ggtggtgata
    10741 aagcagacgc gtggactgct gggctaaaat acgatgctaa caatatttac ctggcaacca
    10801 tgtattcaga aacgcgtaat atgaccccgt ttggcgacag cgattatgct gttgcaaaca
    10861 aaacccagaa ctttgaagtc actgcacagt accagtttga ttttggtctg cgtccggcag
    10921 tctctttcct gatgtctaaa ggccgtgacc tgcacgctgc cggtggtgca gacaatccgg
    10981 caggtgttga tgataaagat ctggttaaat acgccgatgt tggcgcgact tactatttca
    11041 ataaaaacat gtccacctat gttgactata aaatcaacct gttggatgaa gatgacagtt
    11101 tctacgctgc caacggcatc tctaccgatg atattgtcgc tttaggtctg gtttatcagt
    11161 tctaaatccc cctgcccgct gttttggcgg gctttttctg cttattcttc ctcctttgat
    11221 ctaaattaaa aatgtgaact ccgtcattac acaaaaagtg tcatctggcg ttacacttta
    11281 tgcggatact aaaacaggag gttttatgaa cagaacgatt cttgtcccta tcgatatttc
    11341 cgattcagaa ttaactcaac gcgtgattag ccacgttgag gcagaggcaa agattgatga
    11401 tgcagaggtt catttcctga cggtaatacc ttcgctgccc tactatgcct ctctgggttt
    11461 agcgtattcc gcagaattac cggcaatgga tgacctgaaa gcggaagcca aatcgcaact
    11521 ggaagagatc attaaaaaat ttaaactgcc aaccgacaga gtgcatgtcc atgttgagga
    11581 aggctcgccc aaagaccgca ttctggaatt ggcgaagaag atccccgctc atatgatcat
    11641 cattgcttcc catcgaccgg atatcaccac ttatctgctc ggttctaacg ccgcagctgt
    11701 agtgcgtcac gcagagtgct ccgtgctggt tgtgcgctga cactaacgcc cgcacattgc
    11761 tgcgggcttt ttgattcatt tcgcaaatgt g
//
LOCUS       DAPOXO010000122        11598 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPOXO010000122 DAPOXO010000000
VERSION     DAPOXO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11598
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.122"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(378..635)
                     /locus_tag="ROH59_004487"
     CDS             complement(378..635)
                     /locus_tag="ROH59_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001163787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806886.1"
                     /translation="MQHIDRLNVIKALVLLEDEQIVRFNIAANDNASQIHMLVDGLGV
                     GLTHEPVAAGMISHRTACHRSRQHDRPAHSYFYYLSAYQVA"
     gene            complement(689..1456)
                     /locus_tag="ROH59_004488"
     CDS             complement(689..1456)
                     /locus_tag="ROH59_004488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4806887.1"
                     /translation="MSGLTINALCAGYGKRRIIEHLSISTLPRGEVTVLLGPNGCGKS
                     TLLRALAGLNRASGEAWLNEENLLSLPFARRAEKVVFLPQSLPQGVHLQVLESVVVAQ
                     RASGAGQNQAQAIALLEELGIAHLAMNYLDSLSGGQKQLVGLAQSLIRRPELLLLDEP
                     LSALDLNYQFHVMDVVSRETRRRNMVTLVVLHDINIALRHAAQVIMLKEGKLIDSGDP
                     QTVIHAESLAQVYGVRGRVERCAQGRSMVIVDGAIEK"
     gene            complement(1453..2511)
                     /locus_tag="ROH59_004489"
     CDS             complement(1453..2511)
                     /locus_tag="ROH59_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDX4806888.1"
                     /translation="MTVLESTLSVENRYRQLFRQRLVILAVIFIAIIASLLLDFTLGP
                     SGLPLHSLIKTLMHPSGATNGMRVIVWDIRLPYALMALLVGMALGLAGAEMQTILNNS
                     LASPFTLGVSSAAAFGAALAIVLGIGIPGVPESGFIPANAFLFALLSALLLDSLTRWT
                     RVPTSGVVLFGIALVFTFNALVSIMQFVADEDTLQGLVFWTMGSLARASWEKLAVLAA
                     AMAIVLPWSLRRAWQLTALRLGEERAMSFGIDVRRLRLGSLLRISLLAALSVAFVGPI
                     GFIGLVAPHISRLLLGEDHRFYLPGSILIGGLVLSLASVASKNIIPGVILPVGIVTSL
                     VGVPFFLSIVMRHRGSMS"
     gene            complement(2530..3519)
                     /locus_tag="ROH59_004490"
     CDS             complement(2530..3519)
                     /locus_tag="ROH59_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX4806889.1"
                     /translation="MKLSRLFPLLALLLAASLHAENTHKEVRIASPWPAQNTIIAMLG
                     YGDNIVGTSMIAKRIPLFRQSLPRIEKVAAVSVNSGHEINPEQIIALGVDMLFVPQNM
                     VVPQQALLKQAGVQVLAFEANSLRALTQRVQQTAAVLGPDAQQKALAYQRYFDRNVAL
                     VTGRLKDLPASQRVSLYHSMGNPLTTTGRPSLNQDWIDLAGGKNIAENWFGEHQQNRS
                     GEVALEKIVTANPAVIIAMNKRDADAILSSPQWASVDAVIHHRVYVNPKGMFWWCRET
                     SEEALQFLWLAKTLYPARFADVDIRKETREFYRQFFGLTLSDAQMSDVLNPPR"
     gene            complement(3530..5695)
                     /locus_tag="ROH59_004491"
     CDS             complement(3530..5695)
                     /locus_tag="ROH59_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDX4806890.1"
                     /translation="MKTQITFAALLPALASFIPLHAHASSTSEDEMIVTGNTAADTTD
                     SAAGAGFKTNDIDVGPLGTKSWIETPYSSTTVTKEMIENQQAQSVSEMLKYSPSTQMQ
                     ARGGMDVGRPQSRGMQGSVVANSRLDGLNIVSTTAFPVEMLERMDVLNSLTGALYGPA
                     SPAGQFNFVAKRPTEETLRKVTLGYQSRSAFTGHADLGGHFDENKRFGYRVNLLDQEG
                     EGNVHDSTLRRKLVSVALDWNIQPGTQLQLDASHYEFIQKGYVGSFNYGPNVKLPSAP
                     NPKDKNLALSTAGNDLTTDTISTRLIHYFNDDWSMNAGVGWQQADRAMRSVSSKILNN
                     QGDISRSMKDSTAAGRFRVLSNTAGLNGHIDTGSICHDLSLSTTGYVWSLYSAKGTGS
                     SYSWGTTNMYHPDAIDEQGDGKIRTGGPRYRSSVNTQQSVTLGDTVTFTPQWSAMFYL
                     SQSWLQTKNYDKHGNQTNQVDENGLSPNAALMYKITPNTMAYVSYADSLEQGGTAPTD
                     ESVKNAGQTLNPYRSKQYEVGLKSDIGEMNLGAALFRLERPFAYLDTDNVYKEQGNQV
                     NNGLELTAAGNVWQGLNIYSGVTFLDPKLKDTANASTSNKQVVGVPKVQANLLAEYSL
                     PSIPEWVYSANVHYTGKRAANDTNTSYASSYTTWDLGTRYTTKVSNVPTTFRVVVNNV
                     FDKHYWASIFPSGTDGDNGSPSAFIGGGREVRASVTFDF"
     gene            6124..6558
                     /locus_tag="ROH59_004492"
     CDS             6124..6558
                     /locus_tag="ROH59_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806891.1"
                     /translation="MNPSDAIEAIEKPLSSLPYPISRHILEHLRKLTRHEPVPGIMGK
                     SGAGKSSLCNALFQGEVTPVSALMTVLPGHAAIPLMTRLQDELRTESVRTQTREQFTG
                     AVDRIFDTAESVCIASVARTVLRAVRDSVVSVARAVWNWIFF"
     gene            6776..9160
                     /locus_tag="ROH59_004493"
     CDS             6776..9160
                     /locus_tag="ROH59_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HDX4806892.1"
                     /translation="MHEKNIALLCDEADRLLQLNINLLRQMVEEPDVLSDSKNEKRLL
                     FDKQKALKRIEELEGEQIKTARREMVLAVVGTMKAGKSTTINAIVGQEILPNRNRPMT
                     SVPTLIRHVPGKTEPVLHLEHIQPVRNLLITLQEKLATPAGQQVAQTLQQTGDTRELL
                     DILTDDGWLKNEYHGEEEIFTGLASLNDLVRLAAAMGSEFPFDEYAEVQKLPVIDVEF
                     SHLVGMDECQGTLTLLDTPGPNEAGQPQMEVMMRDQLQKASAVLAVMDYTQMNSKADE
                     EVRKELNAIADVSVGRLFVLVNKFDEKDRNGDGADAVCQKVPAMLNSDVLPASRVYPG
                     SSRQAYLANRALHELRKNGTLPVDEAWVDDFVREAFGRMKKDYVCKDSELATEGATDL
                     WEGSLIDQLITEVILSSHSRAAALAVDSAAAKLMQNAENISEYLSLRHQGLMQSIQSL
                     QAHITSLLEDIREIADCQEQVTADVRMAMEEIDARTRELLTGVCTSLEEELNDYFRSG
                     KRKEQQMLEEENSAQPRERNAFAFFLDIFGTGNQHDRMRDFDPDSPEIKFSDRREALE
                     LMTQIESTVTSLHREAEAQFRPELEKIVSGIETGFRGTALYATENIAGRINTRLEDEG
                     FTVKISFPAVSQLQTRLAVKTNLSALMEERTETVTRRRRQSGLWGKICGAFGTSDWGW
                     ETYKEDVSRSVININTVRKEVMSLTRAYFGELQASIEQDINQPVRQEIDAFFCAFREK
                     VEQLRNTLIQSSEDHKRDQQAQERLTRRLQALNERVPELITDSKALREELETML"
     gene            9157..10062
                     /locus_tag="ROH59_004494"
     CDS             9157..10062
                     /locus_tag="ROH59_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HDX4806893.1"
                     /translation="MTSPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAG
                     ERTFFRRLKEGLTGEGAARQNAINASVAQGLEASLRWLTELTTSLATTNYAITRVNDR
                     VSSLVSDTARLAHYSADTREQLLILADQVHHKLNHLEEKLHRVDQVQRAQLHLEQIFS
                     WWSAGRYASFSPAGRCYVALEELRWGAFGDVIRQGETGQVNQLLDILRHKALTQMAQE
                     SGGSATVRLNTLDWLGGQGREQADNEWHDAINWLGDWCSEEQHPVIWSTTQAAEHLPV
                     RMPRLCSAERLSESMVDEIFQKGAG"
     gene            10059..11129
                     /locus_tag="ROH59_004495"
     CDS             10059..11129
                     /locus_tag="ROH59_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDX4806894.1"
                     /translation="MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGTQISMVSGASIG
                     AFNGAIIAASPDLSEAAVRLEALWDHLGNNQVLSVNRLVYFSLLKKLFQAMNLCQIPG
                     RAGALLTTLLRHISILNGFDNLMAQPLLSDEPLTALLDHYLDTDALADGLPLYVSLYP
                     TEGGMQDIIDCIRAELGAGTTKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQG
                     TMFGDGGMGGWRNMQGNTPVTPLVDAGCNMVIVTHLSDGSLWDRQAFPVTTILEIRPR
                     KRLKYAGDGDNSGGLLSFTLAHTDAWRQQGYEDTMLTMEHIRKPLAARQVLSRSETVL
                     QKSLEITEEADLALRNAMARIK"
     gene            11265..>11598
                     /locus_tag="ROH59_004496"
     CDS             11265..>11598
                     /locus_tag="ROH59_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806895.1"
                     /translation="MQLPVKLLMSLISLVSVIARAGKYKNYIRDEIKYWRYTSYKGGE
                     FPEGFTDEKFSSAIYNGRIFTMKRLHTLMLFLAVLFTGFNVEAASVKQALSCDPNARA
                     EQPGACPTT"
BASE COUNT         2840 a         3029 c         3089 g         2640 t
ORIGIN      
        1 gacatatcat tcagtctctc tgaattcttc atttcagtgg ccccggctac agtcgtttaa
       61 tctcctccac gaaccggggc cgcaacttgt tgtgtcaata ccaaattgtt ggtcattact
      121 gtcttgtgtc actggcgctg acaagtgaac tgaaatccgc accttaatat tctgactggc
      181 tgcgtacatt catggcatga agcggccgga gcggctgaac tgaaggtccg ttgtgagcga
      241 acagcggaca ttcactacac atggttcaaa catgaaccgg agctttattg tctagctgtc
      301 agtgtactgc gatttacccg ctcggctgtc cagaaaatcg gtctgaaatc cagtcattaa
      361 agggccttag cctgacatta agcaacttgg taggcggata gataatagaa ataggaatgc
      421 gcaggtctgt catgttgcct agaacggtga caagctgtcc ggtgcgaaat cattccggca
      481 gcgacaggct catgtgtcag cccgacgccc agaccgtcaa cgagcatgtg gatctgcgag
      541 gcgttatcgt tcgcagcgat gttaaaacga acaatctgct catcttctag aagcacaagt
      601 gctttaatga cattaaggcg gtctatatgt tgcattacag acttcctatt gatctttacc
      661 tgaggctgaa gcaaccacgt taatccgact atttttcgat tgcaccatcc actatcacca
      721 tcgatcttcc ctgagcacaa cgttcaactc tcccgcgtac gccgtatacc tgcgcaaggc
      781 tctctgcatg gatcaccgtt tgcgggtcgc cgctgtcgat aagtttcccc tctttcagca
      841 tgatgacctg ggcggcatgc cgcagtgcga tattgatatc gtgtaagacg accagcgtaa
      901 ccatattgcg tcttcgcgtt tcgcgcgata caacatccat cacatggaac tgataattga
      961 gatccagcgc gctcagtggt tcatccagca ataataattc ggggcggcga ataagcgact
     1021 gtgcaagccc caccagctgc ttctgaccgc cggacaggct atcgaggtag ttcattgcca
     1081 gatgtgcgat gcctagctct tcgagcagcg ctatagcctg cgcctgattt tgcccggcgc
     1141 cggaggcgcg ctgggcgaca accaccgact ccagcacctg taaatgcacg ccctgcggca
     1201 gggactgcgg caggaacaca actttttcag cccgacgagc aaacggcagc gataagagat
     1261 tctcttcatt cagccaggct tcgccactgg cgcgatttag cccggccagg gcgcgcagta
     1321 gcgttgattt accgcagcca ttaggcccca gcagtacagt gacttcgccg cgcggcagcg
     1381 tagaaatcga cagatgctca ataatccgcc gtttgccgta accggcgcac agcgcattaa
     1441 tcgtaagccc gctcatgaca tactccctcg atgacgcatt acaatgctca gaaagaacgg
     1501 aacgcctacc agcgaggtaa caattcctac cggtaaaatg acaccgggaa tgatgttctt
     1561 cgacgctacc gaggccagcg atagcaccag cccaccgata aggatgcttc cgggcaaata
     1621 aaagcgatga tcttctccca gcaacaggcg ggaaatatgc ggtgcaacca ggccaataaa
     1681 gccaattggc cccacaaacg caaccgaaag ggccgccagc aggctgatgc gcagcaggga
     1741 acccaggcgc aaacggcgaa catcaatgcc aaaactcatc gcccgctctt cgccgaggcg
     1801 tagcgcggta agctgccagg cacgacgcag cgaccagggt aaaacaatcg ccatcgccgc
     1861 cgccagcacc gccagtttct cccatgatgc gcgagccagg ctgcccatcg tccagaacac
     1921 caggccctgc aaagtatctt catcggcgac aaactgcata atggacacca gcgcattgaa
     1981 ggtaaacacc agcgcaatcc caaacagcac aacgcccgac gtcggcacgc gcgtccagcg
     2041 ggtcagacta tcgagcagca gggcggacag gagcgcaaaa agaaaagcgt ttgccggtat
     2101 aaacccgctt tcgggaacgc cgggaatacc gatgcccaga acaatcgcca gcgctgcgcc
     2161 aaaggccgcc gccgacgaaa cgccaagcgt aaacgggctg gcgagggagt tattcagaat
     2221 agtttgcatc tctgccccgg ccaaacccag cgccattcct accaggagcg ccatcagcgc
     2281 atagggcaaa cggatgtccc aaacgataac ccgcatgccg ttagtcgccc cggacggatg
     2341 catcaaagtc tttatcagcg aatgtaaagg gagccctgag gggccgaggg tgaaatcgag
     2401 cagcagcgaa gcaatgatag cgataaaaat aaccgccagt attaccagac gctggcgaaa
     2461 aagctggcga tagcggttct cgaccgacag cgtactttcc aatacagtca tggtttttca
     2521 cagcctccgt tagcgcggcg gattgagcac atcgctcatc tgcgcatcgc ttaacgtcag
     2581 gccaaagaac tgccgataaa actcacgcgt ctctttgcgt atatccacat cagcaaatcg
     2641 cgcaggataa agcgttttcg ccagccacaa aaattgcagc gcctcttcgc tggtttcacg
     2701 gcaccaccag aacattcctt tcggattaac gtaaacgcga tgatgaatga ccgcgtccac
     2761 gcttgcccac tgcggagaac tcagaatggc atccgcgtcg cgcttgttca tcgcgatgat
     2821 aaccgccgga ttggcagtga caattttctc cagcgcgact tcacccgaac ggttttgttg
     2881 atgctcgcca aaccaatttt cagcgatatt tttgccgccg gccaggtcaa tccagtcctg
     2941 gtttagcgag ggtctaccgg tggtggtcag cggattgccc atactgtgat agagcgacac
     3001 gcgctgtgac gcaggaagat ctttcaggcg cccggtgacc agggccacgt tgcgatcgaa
     3061 gtagcgttga taggcgagcg ctttttgctg cgcatcgggc cccagcaccg ctgccgtttg
     3121 ctgtacgcgc tgcgttaacg cccgcagtga attcgcctca aacgccagca cctgcacccc
     3181 agcctgtttc agcaacgcct gttgaggcac taccatattc tgcggtacaa aaagcatatc
     3241 gacccccagc gcgataatct gttcgggatt gatttcatgc ccgctgttta cgctaactgc
     3301 tgcgactttc tctatgcgcg gcaggctctg gcgaaacagg gggatccttt ttgcaatcat
     3361 cgaggttccg acaatgttat cgccgtaccc cagcatggca ataatggtat tttgcgccgg
     3421 ccacggtgac gcgatacgca cctccttgtg cgtattttct gcgtgcaggc tggccgccag
     3481 cagcagcgcc agcagcggaa ataaacggga gagtttcatc atttatccat cagaaatcga
     3541 aggtgacgga tgcacgcact tcgcggccgc cgccgataaa cgcacttggg gaaccgttat
     3601 cgccatcggt acccgatggg aagatagaag cccagtaatg tttatcaaac acgttgttta
     3661 ccaccacgcg gaaagtggtt gggacgttgc tcactttcgt ggtgtaacgc gttcccaaat
     3721 cccatgtggt atagctgctg gcgtaagagg tgttggtatc gttcgccgcg cgtttgcccg
     3781 tataatggac gttagcgctg taaacccatt ccggtatgga cggcaaactg tattccgcca
     3841 acagattggc ctgcactttc ggcacgccga caacctgttt attgctggtt gaggcattcg
     3901 ccgtatcttt cagtttcggg tcgaggaagg tcacgccgct gtaaatattc agcccctgcc
     3961 acacattccc ggcagcggtt aactcaaggc cgttgttaac ctggttaccc tgctctttat
     4021 acacgttatc cgtatcaaga taggcaaacg gacgttccag tcggaacagc gcggcgccta
     4081 gattcatctc gccgatgtcc gattttagcc ccacttcata ctgcttgctg cgatacgggt
     4141 ttagcgtttg accggcattt tttacgctct catccgtcgg tgcggtaccg ccctgctcca
     4201 gcgaatcggc atagctaacg taggccattg tgttaggggt aattttatac atcagcgcgg
     4261 cgttcggact taaaccattt tcatcaacct ggttcgtttg attaccgtgc ttatcgtagt
     4321 ttttagtctg cagccagctc tggctgagat agaacattgc cgaccactgc ggcgtaaatg
     4381 tcaccgtatc gccgagcgta acgctctgct gagtatttac gctggagcgg tatcgcggcc
     4441 cgccggtgcg gattttgcca tcgccctgct catctatcgc atccgggtga tacatatttg
     4501 ttgtacccca gctatagctg gaacctgttc ctttggcact ataaagcgac cagacatatc
     4561 ccgtggtaga aagtgacaga tcgtggcaga tagagccggt atcaatatga ccattcagcc
     4621 cggcggtgtt gctcaggacg cgaaaacgtc cggcagcggt ggaatccttc atcgaacgag
     4681 agatatcgcc ctgattgttg agtattttac tggaaacact acgcatcgcg cggtcagcct
     4741 gctgccagcc cacgccagcg ttcatggacc agtcgtcgtt aaagtagtgg atcaggcgag
     4801 tgctgatggt atcggtagtg aggtcgttgc ccgcagtgct gagcgccaga tttttgtcct
     4861 tcggattcgg cgcagacggc agtttgacgt tcggcccata gttaaagcta ccgacatagc
     4921 ctttctggat aaattcgtaa tggctggcgt cgagctgtag ctgagtgccc ggctgaatat
     4981 tccagtcgag cgcaacggaa acgagtttgc gacgcagcgt gctgtcatgc acattgcctt
     5041 ccccttcctg atcaagcagg ttcacgcgat agccaaaccg tttgttttca tcaaaatggc
     5101 cacccagatc ggcatggccg gtaaacgcac tgcggctttg atagcccagc gtcactttac
     5161 gcagcgtctc ttcggttggg cgcttcgcca cgaaattaaa ctgccctgct gggctcgccg
     5221 ggccgtacag cgcgccggtc aaactgttaa gcacatccat gcgctcaagc atttccaccg
     5281 gaaacgcggt tgttgaaacg atattcagcc cgtccagacg gctgttggcc accacgctgc
     5341 cctgcatccc ccgactttgc ggacgcccga catccattcc accgcgcgcc tgcatttgcg
     5401 tactgggaga gtatttcagc atctcgctga cgctttgcgc ctgctgattt tcaatcatct
     5461 ctttagtaac agtggtgctg gaatatggtg tttcgatcca ggatttcgtt cccagcgggc
     5521 cgacatctat atcgttcgtt ttgaaaccgg caccggcggc agaatcggtg gtgtcggcgg
     5581 cggtgttgcc cgtgacaatc atttcatctt cagaagtaga cgaggcatga gcatgaagcg
     5641 gtatgaaaga cgctaatgct ggcaaaagcg cagcgaaagt tatttgagtt ttcatgaatc
     5701 actgatcgtt atgtaaatat ttatattacg atcggtgcat aggcaaaatt atgatccaga
     5761 tcacacgtga atgtaagtta tttacaaatt acgctaacct tctgtctccg ctctttgcag
     5821 cataaaagta tggcggcgcg ttgttgaaag caggagcggc cgggttgtca gaaagctggt
     5881 ttggacgcaa gtaatatata acaactctga ttaccgcata ctgtcaggac agtatctact
     5941 tgagcgtccg cctttggcac aaagcggact gtcagattag attcagacct gtactcatta
     6001 gctgatacaa atcagccaca tatacctgca ttcaaaataa tttcagaaag atattatctc
     6061 cgtgaatccc ccgccacctt tccggtgcac ggggttttgt cttttttcac tgggaataca
     6121 tgtatgaatc cgtctgatgc cattgaggca attgaaaaac cgctctcctc cctgccttac
     6181 ccgatttccc gtcacatcct ggaacatctg cgcaaactca cccgtcacga acccgtgcct
     6241 ggcattatgg gtaaaagcgg ggccggtaaa tcctcactct gtaatgcact gtttcagggg
     6301 gaggtcaccc cggtcagtgc actcatgaca gtgcttcccg gacatgccgc catccctctg
     6361 atgacacgcc tgcaggacga actgcgcacg gagtctgtcc gcactcagac ccgtgaacag
     6421 tttaccggtg cggtggaccg gatatttgac acggcggaga gtgtctgcat tgcctctgtt
     6481 gcacgcacgg ttctgcgcgc cgtccgtgac tcggtggtct ctgttgcccg cgcggtatgg
     6541 aactggattt tcttctgaac ccggtggtga tgtaccaggc tgttgttaca gatttttaac
     6601 tccatgaaaa cactatgcaa acgcagccat acccggggtg tccccttgcg ttgtgttttt
     6661 caagttaata gaatacatcg atcgttacta tcatatcgat cgttataaac gatcgtttgt
     6721 ggtaaatgac ctcctccgtg gttgtcatga aaatgcgtct caggaaggtt aaataatgca
     6781 cgaaaagaac atcgccctgc tttgtgatga agccgaccga cttttgcaac tgaacattaa
     6841 tctgctccgg caaatggttg aggagccaga tgtgttatct gacagtaaga acgaaaaaag
     6901 actgcttttt gataaacaga aagcactgaa aagaattgag gagctggagg gcgaacaaat
     6961 caaaaccgcc cgcagggaga tggtgctggc tgttgtcggc acgatgaaag caggtaaatc
     7021 aaccaccatc aacgccattg tggggcagga aattctgcct aaccgtaacc gccccatgac
     7081 ctctgtaccg acgctcatcc gccacgttcc cggaaaaact gagccggttc tccatctgga
     7141 acatattcag cctgtccgca atttattaat cacactgcag gaaaaactcg ccaccccggc
     7201 aggacagcag gtcgcacaga ccctgcagca aaccggggat acccgcgaac tgctggatat
     7261 tctgacggat gatggctggc tcaaaaatga ataccacggg gaggaggaaa tctttaccgg
     7321 actggcatcg ttaaacgatc tggttcgtct tgctgcggca atggggagtg aatttccttt
     7381 tgatgaatac gcagaagtgc agaaactgcc ggtgatcgac gtggaattca gccatctggt
     7441 ggggatggat gaatgccagg gaacactcac actgctggat acccccggcc ctaatgaagc
     7501 cggacaaccg cagatggaag tgatgatgcg ggatcaactg cagaaagcct ctgcggtgct
     7561 ggcggtgatg gactacaccc agatgaactc gaaagccgat gaggaggttc gtaaagagct
     7621 taatgccatt gctgatgtgt ctgtcggccg cctgtttgtg ctggtcaata aatttgatga
     7681 aaaagaccgt aatggcgatg gggctgatgc agtctgtcag aaggtaccgg caatgctgaa
     7741 cagcgatgtg ctgcccgcct cccgcgttta tcccggatcc tcacgccagg catacctggc
     7801 taaccgtgcg cttcatgagt tacggaaaaa cggaaccctt cctgttgatg aagcctgggt
     7861 cgatgatttt gtcagggaag ccttcggtcg catgaaaaaa gattacgtct gtaaagacag
     7921 cgaactggca actgaagggg cgacagacct gtgggaaggc tcacttatcg atcaactgat
     7981 aacggaagtc atactgagtt cacactccag agctgcggca ctggcggttg attctgccgc
     8041 cgcaaaactg atgcagaatg cagaaaatat cagtgaatac ctgtcgttac gccatcaggg
     8101 gctgatgcaa agtattcagt cactgcaggc gcatatcacc agcctgcttg aggatatccg
     8161 ggaaatagca gactgtcagg agcaggtgac cgctgatgtc agaatggcca tggaggagat
     8221 cgatgccaga acccgggaat tactgacggg ggtctgcacc tcactggaag aggagctgaa
     8281 tgactatttc agaagcggta aacgcaaaga acagcaaatg ctggaggaag aaaattcagc
     8341 gcagccccgg gagagaaacg cattcgcttt ctttctcgat attttcggaa ccggaaatca
     8401 gcatgacagg atgcgggact ttgatcccga cagccccgaa ataaaattca gtgatcgcag
     8461 ggaagccctt gaactgatga cgcaaatcga atcgaccgtg accagcctgc accgtgaggc
     8521 tgaagcacag ttccggcctg agctggagaa aatcgtcagc gggattgaaa caggttttcg
     8581 tggcacggcc ctgtacgcca cagaaaacat tgccggtcgc atcaataccc gcctggagga
     8641 tgagggcttt accgtaaaaa tcagttttcc ggcagtcagt cagttacaaa cccggctcgc
     8701 ggtaaaaaca aatctgagtg cgcttatgga ggaaagaacg gagaccgtca cccgtcgccg
     8761 tcggcagagt ggtttatggg gaaagatttg tggagcgttt ggcaccagtg actggggctg
     8821 ggaaacctat aaagaggatg tgagccgcag tgttatcaat atcaacaccg tcaggaagga
     8881 agttatgtca ctgacccggg catatttcgg ggagctgcag gcatccattg agcaggatat
     8941 taaccagccc gtccgccagg aaatcgatgc ctttttctgc gcattcaggg agaaagttga
     9001 acaactgcgt aacacgctga ttcagagctc tgaagatcat aaacgcgatc agcaggcaca
     9061 ggaacggctt accaggagac ttcaggcatt aaatgaaagg gttcctgagc tcattactga
     9121 cagtaaggcg ctgagggaag agctggagac aatgctgtga cttcaccatt tattcaacaa
     9181 attgctgata accgggtatg tcaggtactc acctgtcttc ctgaaaaatt tgtggttgat
     9241 ttcgcaaacg gaatcgatgt tgcacaggag catatccgca cggccggaga gcgcacgttc
     9301 ttccggcgtt taaaagaggg actgaccggc gaaggcgctg cacggcagaa tgccatcaat
     9361 gcttcggttg cacagggcct tgaggcgtcc ctgcgctggc tgacggagct gacaacgtca
     9421 cttgccacca caaactacgc gattacccgg gtaaacgaca gggtcagttc actggtcagt
     9481 gatactgcca ggctggcgca ttattccgca gatacacggg agcagttact catcctggcc
     9541 gatcaggttc accataaact gaatcatctt gaagaaaaac tccaccgtgt tgaccaggtt
     9601 cagcgggcgc agttacatct tgagcagata ttctcatggt ggagcgccgg gcgatatgcg
     9661 tcattttccc ctgccggacg ttgttatgtg gcgcttgaag agcttcgctg gggcgcgttt
     9721 ggtgatgtga tacgtcaggg cgaaacaggc caggttaacc agctactgga tattctcaga
     9781 cataaagcat taacgcagat ggcacaggag agtggcggta gtgcaaccgt gcgtctgaac
     9841 actctggact ggcttggtgg tcagggccgg gagcaggcag ataacgagtg gcatgacgcg
     9901 attaactggc tgggagactg gtgcagtgaa gagcagcatc cggtgatctg gtcaaccacg
     9961 caggctgcag aacacttacc ggttcgcatg cctcgcctct gctctgcaga acgcctctct
    10021 gaaagtatgg tcgatgaaat atttcagaag ggggctggat gagtacagaa atgaaaacgg
    10081 ggctggtgct gtccggtggc ggggcggtgg gcgcttatca ggcgggagtg gttaaggcac
    10141 tggcagagtg tggtacacag atcagcatgg tttcaggggc cagcattggc gcattcaatg
    10201 gtgccattat cgcggcctct cccgatctgt cagaagctgc cgtacgcctg gaggcgctct
    10261 gggatcatct ggggaataat caggtgctgt cggtaaaccg attggtttac ttttcattgc
    10321 tgaaaaaatt gttccaggca atgaacctct gccagatccc cggacgtgca ggagcactgc
    10381 ttacgacgct tcttcgccat atatcgatac tcaacgggtt tgacaatctg atggctcagc
    10441 cgttgttgtc agatgagccc ctgacagcgc tgttggatca ttatcttgat actgatgctc
    10501 tggcagacgg gctaccgctg tatgtgtcgc tgtaccccac agaagggggc atgcaggata
    10561 ttattgactg cattcgtgct gaactgggtg ccggaaccac gaaaaacgcc gtttttcagc
    10621 atatccagag cctgccccgc ggacagcaga aagaggctct gcttgcgtca gccgcgctgc
    10681 ccctgctgtt ccgtccccgt gaggttcagg ggacaatgtt cggtgatggt ggtatgggag
    10741 gatggcgaaa tatgcaggga aatacccctg tgacgcctct ggtcgatgcc ggatgcaata
    10801 tggtgattgt gacgcatctg agtgacggtt ctttatggga tcgccaggct tttccggtca
    10861 ccacaatcct tgagatccgt ccccggaaaa ggctgaaata tgcaggtgat ggtgacaaca
    10921 gcggcggtct gctcagtttc acgttggcac ataccgacgc ctggcgtcag cagggctatg
    10981 aagacacgat gctgacgatg gagcatatcc ggaaaccgct ggcagcacgt caggtactgt
    11041 cccggtcaga aacggtgttg cagaaaagtc tggagataac ggaagaggca gatttggcac
    11101 tgagaaacgc gatggcccgg attaaataaa gacgccccaa agaaacgcca ccgcctgtgg
    11161 tggtgttttt cctggctggt gttattgaaa atattttcag atatatatta cctgagagaa
    11221 agttttaccc ctcacctgtc aattcactca ctggaaattt aattatgcaa ttacctgtaa
    11281 agttattaat gagccttata tctctggtca gcgttattgc acgtgccggg aaatataaaa
    11341 attacatccg ggatgaaata aaatactggc gatatacatc atacaagggg ggggaatttc
    11401 cggaaggttt cactgatgag aaattttcca gcgccattta caacggaaga atatttacaa
    11461 tgaaacgttt acataccctg atgttatttc tggcggttct gtttactggc tttaacgtgg
    11521 aagcagcgag cgtgaaacaa gcgctcagct gcgacccaaa cgcccgggct gaacaacctg
    11581 gagcgtgtcc aacaacgt
//
LOCUS       DAPOXO010000123        11590 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.123, whole genome shotgun sequence.
ACCESSION   DAPOXO010000123 DAPOXO010000000
VERSION     DAPOXO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11590
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.123"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            76..891
                     /gene="gspC"
                     /locus_tag="ROH59_004497"
     CDS             76..891
                     /gene="gspC"
                     /locus_tag="ROH59_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HDX4806896.1"
                     /translation="MPTLPFPFHLANHNKDAAINILITFISIGLIIFNVNYFHTTIVK
                     NEQIINQPTNAFQSEFSLAALWRNENHTGVKDANPVAVNQETPKLSIALNGIVLTSND
                     ETSFVLINEGNEQKRYSLNEALESAPGTFIRKINKTSVVFETHGHYEKVTLHPGLPDI
                     IKQPDSENQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNL
                     SLTHPDEISQALSLLLTQQSAQFTIRRNGVPRLINVSVAELTGMNGQRNEGTQ"
     gene            875..2827
                     /gene="gspD"
                     /locus_tag="ROH59_004498"
     CDS             875..2827
                     /gene="gspD"
                     /locus_tag="ROH59_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HDX4806897.1"
                     /translation="MKGLNKITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIV
                     GQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVR
                     SANVKTSPGMIADSSRPGVGDELVTRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYE
                     PSNVLILTGRASTINKLIEVIKRVDVIGTEKQQIIHLEYASAEDLAEILNQLISESHG
                     KSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNTRVYYLKYA
                     KATNLVEVLTGVSEKLKDEKGNSRKPSSTSAMDNVAITADEQTNSLVITADQSVQEKL
                     ATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPVFNAAQG
                     VADYKKNGGITSANPAWDMFSAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVT
                     LDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERKTVGTKLKVTPQVNEGDAVLLEIE
                     QEVSSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI
                     PLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLSKEKYTRYRQEQQLRIDGKSK
                     ALVGSEDLPVLNENTFNSHAPAPSSR"
     gene            2837..4318
                     /gene="gspE"
                     /locus_tag="ROH59_004499"
     CDS             2837..4318
                     /gene="gspE"
                     /locus_tag="ROH59_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HDX4806898.1"
                     /translation="MRIHSPYPASWALAQRIGYLYSEGEIIYLADTPFERLLDIQRQV
                     GQCQTMTSLSQADFEARLEAVFHQNTGESQQIAQDIDQSVDLLSLSEEMPANEDLLNE
                     DSAAPVIRLINAILSEAIKETASDIHIETYEKTMSIRFRIDGVLRTILQPNKKLAALL
                     ISRIKVMARLDIAEKRIPQDGRISLRIGRRNIDVRVSTLPSIYGERAVLRLLDKNSLQ
                     LSLNNLGMTAADKQDLENLIQLPHGIILVTGPTGSGKSTTLYAILSALNIPGRNILTV
                     EDPVEYELEGIGQTQVNTRVDMSFARGLRAILRQDPDVVMVGEIRDTETAQIAVQASL
                     TGHLVLSTLHTNSASGAVTRLRDMGVESFLLSSSLAGIIAQRLVRRLCPQCRQFTPVS
                     PQQAQMFKYHQLAVTTIGTPVGCPHCHQSGYQGRMAIHEMMVVTPELRAAIHENVDEQ
                     ALERLVRQQHNALIKNGLQTVIRGDTSWDEVMRVASATLENKA"
     gene            4315..5511
                     /gene="gspF"
                     /locus_tag="ROH59_004500"
     CDS             4315..5511
                     /gene="gspF"
                     /locus_tag="ROH59_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HDX4806899.1"
                     /translation="MNYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQ
                     KSSGVKTRRPRISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLADVLNQVR
                     SAILEGHPLSDALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKL
                     IQSLIYPCMLTTVAIVVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRTG
                     PTLLATVFIVAVGFWLWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQS
                     SGVPLLDGMNLSTESLNNLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVAS
                     GEKSGQLGTLMVRAADNQETLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQ
                     LNSMIN"
     gene            5521..5958
                     /gene="gspG"
                     /locus_tag="ROH59_004501"
     CDS             5521..5958
                     /gene="gspG"
                     /locus_tag="ROH59_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HDX4806900.1"
                     /translation="MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQK
                     AVSDIVALENALDMYKLDNHRYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADP
                     WGNDYVLVNPGEHGAYDLLSAGPDGEMGTEDDITNWGLSKKKK"
     gene            5966..6475
                     /gene="gspH"
                     /locus_tag="ROH59_004502"
     CDS             5966..6475
                     /gene="gspH"
                     /locus_tag="ROH59_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HDX4806901.1"
                     /translation="MNQQRGFTLLEMMLVLALVAITASVVLFTYGREDAASTRARETA
                     ARFTAALELAIDRATLSGQPVGIHFSDSAWRIMVPGKTPSAWRWVPLQEDAADESKND
                     WGEELSIQLQPFKPDDSNQPQVVILADGQITPFSLLMANTGTGEPLLTLVSSGSWPLD
                     QTLARDTRP"
     gene            6472..6849
                     /gene="gspI"
                     /locus_tag="ROH59_004503"
     CDS             6472..6849
                     /gene="gspI"
                     /locus_tag="ROH59_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417789.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HDX4806902.1"
                     /translation="MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQRTAIERMRNET
                     LALWIADNQLQSQDSFDEENTSSSGKELINGEEWNWRSDIHSSKDGTLLERTITVTLP
                     SGQTTSLTRYQSINNKSGQAQDD"
     gene            6842..7429
                     /gene="gspJ"
                     /locus_tag="ROH59_004504"
     CDS             6842..7429
                     /gene="gspJ"
                     /locus_tag="ROH59_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HDX4806903.1"
                     /translation="MINRQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKE
                     IQQFNQLQRTITILDNDLLQLVARRNRSTDKIMVLGEEAIFTTQSRDPLAPLSEAQTL
                     LTVHWYLRNHTLYRAVRTSVDGRKDQPAQAMLEHVESFLLESNSGESQELPLSVTLHL
                     KTQQYGALQRRFALPEQLAREESPAQTQAGNNNHE"
     gene            7422..8405
                     /gene="gspK"
                     /locus_tag="ROH59_004505"
     CDS             7422..8405
                     /gene="gspK"
                     /locus_tag="ROH59_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HDX4806904.1"
                     /translation="MNNEQRGVALLIVLMLLALMAALAADMTISFHGQLHRTRQVNHH
                     LQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLENGNTVKWQLRDAQH
                     CFNLNALAKISDAPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDADDSPRF
                     HGAEDNFYQSQTPPRHSANQMLFLTGELRQIKGITENIYQRLIPYVCVLPTSELSINL
                     NMLTENDIPLFRALFLNNITDADARVLLQKRPREGWLTTDAFLYWAQQDFSGVKPLVA
                     QVKGHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQSAQIYRRTLQLY"
     gene            8420..9583
                     /gene="gspL"
                     /locus_tag="ROH59_004506"
     CDS             8420..9583
                     /gene="gspL"
                     /locus_tag="ROH59_004506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HDX4806905.1"
                     /translation="MPESLMVIRSFSTLRKHWEWMTFSADSVSSVHTLTDDLPLGSLA
                     DQPGAGNVHLLIPPEGLLYRSLTLPNAKYKLTAQTLQWLAEETLPDASQNWHWTVVDK
                     QNESVEVIGIQSEKLSRYLERLHTAGLNVTRVLPDGCYLPWEVDSWTLVNQQTSWLIR
                     SAAHAFNELDEHWLQHLANQFPPENMRCYGVAPHGVAAANPLIQHPEIPSLSLYSADI
                     AFQRYDMLHGVFRKQKTVGKSGKWLTRLAVSCLVLAILSFVGSRGIALWQTLKIEDQL
                     QQQQQETWQRYFPQIKHTHNFRFYFKQQLAQQYPEAVPLLYHLQTLLLEHSELQLMEA
                     NYSQRQKSLTLKMSAKSEANIDRFCELTQSWLPMEKTEKDPVSGVWTVRNSGK"
     gene            9580..10041
                     /gene="gspM"
                     /locus_tag="ROH59_004507"
     CDS             9580..10041
                     /gene="gspM"
                     /locus_tag="ROH59_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspM"
                     /protein_id="HDX4806906.1"
                     /translation="MIKSWWAEKSTSEKQIIAALAVLSLGVFCWLAVIKPIDTYIEEH
                     QSHAQKIKKDIKWMQDQASTHGLLGHPALTQPIKNILLEEAKRENLTITLENGPDNTL
                     TINPVTAPLENVSRWLTTAQITYGIVIEDLQFTLAGNEEITLKHLSFREQQ"
     gene            10041..10713
                     /gene="gspO"
                     /locus_tag="ROH59_004508"
                     /pseudo
     CDS             10041..10713
                     /gene="gspO"
                     /locus_tag="ROH59_004508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase GspO"
     gene            complement(10742..11218)
                     /gene="bfr"
                     /locus_tag="ROH59_004509"
     CDS             complement(10742..11218)
                     /gene="bfr"
                     /locus_tag="ROH59_004509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HDX4806907.1"
                     /translation="MKGDTKVINYLNKLLGNELVAINQYFLHARMFKNWGLKRLNDVE
                     YHESIDEMKHADRYIERILFLEGLPNLQDLGKLNIGEDVEEMLRSDLALELDGAKNLR
                     EAIGYADSVHDYVSRDMMIEILRDEEGHIDWLETELDLIQKMGLQNYLQAQIREEG"
     gene            complement(11290..11484)
                     /gene="bfd"
                     /locus_tag="ROH59_004510"
     CDS             complement(11290..11484)
                     /gene="bfd"
                     /locus_tag="ROH59_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HDX4806908.1"
                     /translation="MYVCLCNGISDKKIRQAVRQFSPHSFQQLKKFIPVGNQCGKCVR
                     AAREVMEDELMQLPEFKESA"
BASE COUNT         3065 a         2956 c         2722 g         2847 t
ORIGIN      
        1 tgcaagcggc attaatacta tttatactaa cgtcaatata caacccaccc aatctatttt
       61 attagaacat acatcgtgcc cacactacct ttccccttcc atctggcgaa tcataataaa
      121 gatgctgcca tcaatatatt gattacattt ataagcatag ggctgattat ttttaatgtg
      181 aattatttcc atacaactat agttaaaaat gaacagatca ttaatcaacc aacaaatgca
      241 tttcagtctg aattcagcct tgccgcttta tggcgcaacg aaaatcatac tggggtaaaa
      301 gatgcaaatc ccgtggcagt taatcaggaa acacctaagc tctctatagc gcttaatggc
      361 attgtactca catcgaatga tgagacttct tttgtcttaa ttaatgaggg gaacgaacaa
      421 aagcgatact ccctcaacga agcccttgag tcagcgccgg gaacgtttat tagaaaaata
      481 aataaaacca gcgttgtgtt tgaaactcac gggcattacg aaaaagtaac tctccatcca
      541 gggctacctg acatcatcaa gcagcctgat tcggaaaatc aaaatgtact cgccgattat
      601 attatcgcca cacctatacg tgatggagaa cagatatacg gtcttcgatt gaatcctcgt
      661 aagggtctca atgcatttac caccagtttg ctgcaacctg gggatatcgc cctcaggatc
      721 aataatcttt cgctgaccca ccctgatgag atttcacagg cattaagttt actgctaact
      781 caacaaagtg ctcagtttac aattcgtcgc aacggcgtac cccgcttgat aaatgtttcc
      841 gtcgcggaac ttacaggaat gaatggacag cgcaatgaag ggactcaata aaatcacctg
      901 ctgcttgctg gcagcattac tcatgccttg tgcaggacac gctgagaacg aacaatacgg
      961 cgctaacttc aataacgccg atatccgcca gttcgtggaa atagtgggtc agcatcttgg
     1021 caaaacgatc ctgatcgacc cttcggtaca gggaaccatt tccgtacgca gtaatgatac
     1081 gtttagccaa caggagtact accagttctt tttaagtatt cttgatcttt acggttattc
     1141 cgtgatcacg ctggacaatg gttttctgaa agtggtgcgc tcagctaatg taaaaacatc
     1201 gccagggatg attgctgaca gttctcgtcc aggcgtaggt gatgagttgg tcacccgaat
     1261 cgtaccgctt gagaacgttc ctgctcgtga cctggctccc ctgctccgcc agatgatgga
     1321 tgcgggtagc gtcggtaatg ttgtgcatta tgaaccctcc aacgttctta ttctgaccgg
     1381 tcgtgcctcc accattaata aactgattga agtcataaag cgcgttgatg tcatcggcac
     1441 agagaagcag caaattattc atctggaata tgcatcagcg gaagatctcg ccgagattct
     1501 taatcaatta atcagcgaaa gccacggtaa aagccagatg cctgccctcc tttccgcgaa
     1561 gattgtggcg gataagcgaa ccaactctct tatcatcagc ggaccggaaa aagcacgcca
     1621 gcgcataact tcattactga aaagccttga tgtagaagag agcgaggaag gaaatacccg
     1681 ggtctattac ctgaaatatg ctaaagccac gaatctggtg gaagtgctaa ccggtgtttc
     1741 cgaaaagctg aaagatgaaa aagggaattc gcgtaagcct tcttctactt ctgcgatgga
     1801 taatgtggcc attaccgccg atgaacagac caactcgttg gtcattaccg ctgaccagtc
     1861 cgtccaggag aaactcgcca cggtaattgc gcgtctggat attcgccgtg cacaggtgct
     1921 ggttgaggca atcatcgtcg aagttcagga tggaaatgga ctcaacctcg gcgtgcaatg
     1981 ggcgaataaa aacgttggcg cacagcaatt taccaatacg ggattaccgg tttttaacgc
     2041 tgcgcaaggt gtagctgatt ataaaaagaa tggcgggatc accagcgcga atcctgcctg
     2101 ggatatgttt agcgcctaca atggcatggc tgcaggcttc ttcaatggcg actggggcgt
     2161 attgttgact gcgctggcca gtaacaataa aaatgacatc ctcgccaccc cgagcatcgt
     2221 aacgctggat aataaactcg cgtccttcaa cgttggtcag gatgtgccgg tgctatccgg
     2281 ctctcagacc acttctgggg ataacgtctt taatactgtc gaacgcaaaa cggtgggcac
     2341 aaaactcaaa gtcactccgc aggtcaatga aggcgacgcg gtactgctcg aaatagaaca
     2401 ggaggtttcc agcgttgact cttcgtctaa ttcgacgctc ggcccgacat ttaacacccg
     2461 tactattcaa aacgccgtgc tggttaaaac cggtgaaacg gtggtcctgg gcggattgct
     2521 ggatgatttt tctaaagagc aagtgtcaaa ggttcctctg cttggcgata ttcctttagt
     2581 gggacaactc ttccgctata cctcgaccga gcgcgctaaa cgcaacctga tggtattcat
     2641 ccgcccgacg attatccgtg acgatgatgt ttatcgctca ctgtcaaaag agaaatacac
     2701 ccgctaccgt caggagcaac agctgcgaat cgacgggaaa tcaaaagcgc tggttggctc
     2761 ggaagatttg ccggtgctga atgagaacac gttcaacagt cacgcccctg cgccatcgtc
     2821 acggtgaggc attcttatga gaattcactc accgtacccc gccagttggg cgctggcaca
     2881 acgaattggt tatctctatt cagagggcga gattatttat ctcgccgata cgccattcga
     2941 acggttactc gatattcaac gtcaagttgg tcagtgccag accatgacca gcttgtcaca
     3001 ggctgatttt gaagcccgac tggaagcggt gttccatcag aataccggtg agtcgcaaca
     3061 gattgcgcag gatatcgatc aatccgtcga tcttctctcg ctttcggaag agatgcccgc
     3121 aaatgaagat ctcctgaatg aagattcagc ggcaccggtt atccgcttga tcaatgctat
     3181 tttgagtgag gccatcaaag aaaccgcctc cgatatccac attgaaacct atgaaaaaac
     3241 aatgtcgatc cgttttcgca tcgacggcgt tttgcggaca attttacagc ccaacaaaaa
     3301 actggcggca ctgcttatct cccgaattaa ggtcatggct cgtcttgata tcgccgaaaa
     3361 acgtattcca caggatggaa ggatcagttt gcgtatcggg cgacgtaaca tagatgtccg
     3421 cgtatccaca ctgccatcca tctatggtga acgcgctgtg ctccgtctgc tggataaaaa
     3481 cagcctccag ctttcattga acaacctggg gatgacggca gcggataaac aggatttaga
     3541 aaatctcatt cagcttccgc acggtattat cctggtgaca gggccgacag gctccggtaa
     3601 aagcaccacg ctctacgcca tcctttcggc gcttaatatc cctggccgta atattctgac
     3661 ggtagaagat cccgtggaat atgagctgga aggcattgga caaacgcagg tgaatacccg
     3721 tgtggatatg tctttcgctc gcggcctgcg cgccatactt cgccaggacc cggatgtcgt
     3781 catggtgggg gaaattcgtg atacagaaac cgcgcaaatt gcggttcagg cctcgctcac
     3841 aggccatctg gtactctcaa cactccacac taacagtgca tcaggcgcag tcacccggct
     3901 acgcgacatg ggcgtcgaat cattcctgct ttcatcttca ctggcaggga ttatcgcgca
     3961 acgtctggtt cgtcgtctgt gtccgcaatg ccgacaattc acgcccgtat cgccccagca
     4021 agcgcagatg tttaaatatc atcagctcgc ggtgacaaca attggcactc ccgtaggttg
     4081 ccctcattgc catcaatccg gttatcaggg gcgcatggcg atccacgaaa tgatggtggt
     4141 gacgccggaa ttgcgggccg ctattcatga aaatgtggat gaacaagcac tggagcgact
     4201 ggtccggcaa caacacaatg ccttaatcaa aaatggcctg caaacagtga tacgcggtga
     4261 cacctcctgg gatgaggtta tgcgcgtcgc cagtgctacg ctggagaaca aagcatgaat
     4321 tatcgctatc gcgccatgac ccaggatggt caaaaattgc aggggatcat tgatgctaac
     4381 gatgaacgtc aggcacgact gcggctgcgt gaagaagggc ttttcctgtt ggatattcgc
     4441 ccccaaaaaa gttcgggagt aaaaacacgt cgcccgagga tcagccatag tgaactgacg
     4501 cttttcaccc ggcagttggc aaccttaagc gcagcggcat tacccctgga agagagcctt
     4561 gccgtaattg gtcaacaaag cagtaataaa cgactggctg acgtgttaaa tcaggtacgc
     4621 agcgccatcc ttgaagggca tcccctttca gatgcattac agcatttccc cacgcttttc
     4681 gattcgctct accgtaccct ggtaaaagcg ggcgaaaaga gcggtctgct ggccccggtg
     4741 ttggaaaagc tggctgatta caatgaaaac cggcagaaaa tccgcagcaa gctcattcag
     4801 tcactgatct acccctgcat gctcactacg gtggcgattg tggtcgtgat tattctcctc
     4861 actgctgtcg tgcccaaaat taccgaacag ttcgtgcata tgaagcagca actgccactg
     4921 agtacacgca ttcttttagg tctgagcgac acgttgcaac gtaccggccc gacattatta
     4981 gcgacagtat ttattgtcgc tgtgggtttc tggctctggt taaaacgcgg caataaccgc
     5041 caccgttttc atgccatgtt actgcgcgtt gcgctcatcg gcccgctgat ttgcgccatt
     5101 aacagcgcac gctatctccg cactttaagt attttgcaat ccagcggcgt ccctctgctg
     5161 gatgggatga atttgtccac cgaaagcctc aacaacctcg aaattcgcca gcgcctggca
     5221 aatgcggcag aaaacgttcg ccagggtaac agcattcatc tttcactgga acaaaccgca
     5281 attttcccgc cgatgatgct ctacatggtg gcctctggcg aaaaaagcgg gcaactcggc
     5341 acgttaatgg tcagagccgc agataaccag gagacactcc aacaaaatcg gatcgcctta
     5401 acgctctcca tcttcgagcc agcactcatt attacgatgg cactgatcgt cctgtttatt
     5461 gtcgtgtcgg tactccaacc tcttcttcaa cttaactcaa tgattaatta aggaaatcat
     5521 atgcgcgcaa cggataagca acgcggtttt acattactgg aaattatggt ggtaattgtc
     5581 atcattggcg tactcgccag cctggtggtt cccaacctga tgggcaataa agaaaaggcg
     5641 gataaacaaa aagccgtcag cgatattgtg gcgctggaaa acgccctgga tatgtacaag
     5701 ctcgacaatc atcgctatcc aaccacaaat caggggcttg aatccttagt agaagcgccg
     5761 acactgccac cgctggccgc aaactataac aaggaaggtt atatcaagcg tctgcctgcc
     5821 gatccctggg gcaatgatta tgtcctcgtt aatcctggtg aacatggtgc atacgatctg
     5881 ctttcagcag gacccgatgg tgaaatggga accgaggacg acatcaccaa ctggggtttg
     5941 agcaagaaga aaaagtaagt cagcgatgaa tcagcaacgc gggtttaccc tgctggagat
     6001 gatgctggtg ctggcgctgg tcgctatcac ggcaagtgtg gtgctcttca catatggtcg
     6061 ggaggatgcc gccagcactc gtgcgcgcga aacagcggcg cggtttaccg ctgcacttga
     6121 attagccatc gaccgcgcca cgctcagtgg tcagcctgtc ggtatccatt tctctgattc
     6181 agcatggcgc attatggtac cgggcaaaac accatcagcc tggcgctggg ttccattaca
     6241 agaagatgcc gcagacgaga gcaaaaatga ctggggtgaa gaactctcaa ttcaacttca
     6301 gccatttaaa cctgatgaca gcaaccaacc gcaggtggtg attctggccg acggacaaat
     6361 cacgcccttc tctttgttga tggctaatac cgggaccggt gagccgctcc tgacgttagt
     6421 cagttcaggc tcatggcccc tggatcaaac gctcgccaga gatacccgcc catgaacaaa
     6481 caatcaggga tgacactgct tgaagtctta ctggcgatga gtattttcac cgctgttgcg
     6541 ctgactttaa tgagcagtat gcaagggcaa cgaactgcca tcgagcggat gcgtaacgag
     6601 acgctggcat tgtggatagc ggataaccag cttcagtcac aagattcatt cgacgaggaa
     6661 aacacgtcca gttctggcaa agagttaata aatggcgaag agtggaactg gcgcagcgat
     6721 atccactcaa gcaaagacgg cacgcttctg gaacgcacca taacggtgac attacccagc
     6781 ggccagacaa cctcgcttac gcgctatcaa agcatcaata ataaatccgg gcaggcacaa
     6841 gatgattaat cgccagcagg gtttcacatt gctggaagtc atggcggcgc tggcgatttt
     6901 ctcaatgctt agcgtgctgg cgtttatgat tttttctcaa gcttccgagt tgcatcaacg
     6961 ttcacagaaa gaaatccagc agttcaatca gctacagcgc accatcacca ttcttgataa
     7021 cgatctcctg caactggtcg cccggcggaa tcggagtacg gacaaaatca tggtgttggg
     7081 tgaagaagcg atttttacca cgcaaagtcg cgatccgctg gcccctctca gtgaagcaca
     7141 aaccttactc actgttcact ggtatctgcg aaatcatacg ctctaccgtg ctgttcgtac
     7201 ttctgtggat ggcaggaagg atcaacccgc ccaggcgatg ctggaacatg tcgagagctt
     7261 tcttctggaa agtaacagcg gagaaagcca ggagcttcct ctctcagtca cgttacatct
     7321 gaagactcag caatatgggg cgttacagcg ccgttttgca ttacctgagc agttagcgag
     7381 agaagagtcg ccagctcaga cgcaggccgg gaataataac catgaataat gaacaacgcg
     7441 gcgtagcact gctcattgta ctcatgttac tggcgctcat ggctgctctg gctgcagaca
     7501 tgacgatcag ttttcacggc cagcttcatc gaacccgcca ggtaaaccat catttgcaac
     7561 ggcaatatga tattgagctg gcggagaaac ttgcgcttgc cagcctcacc caggacgtta
     7621 aagataacga cagacaaacc acgttgcagc agtactgggc acaaccgcaa cagttgcagc
     7681 tggaaaatgg caatacagtg aagtggcagt tacgcgatgc ccagcactgt tttaatctca
     7741 atgccttagc aaaaatctct gacgccccgc tggcttcccc tgatttcccc gcccaggtat
     7801 tcagtgccct gctgattaac gccggtatcg atcgcggaaa caccgatgag atcgtgcaat
     7861 caatcgctga ctatattgat gccgatgatt cgccacgctt tcacggcgca gaagataact
     7921 tttaccaaag ccaaacgccg cctcgccata gcgccaatca aatgcttttt ctgaccggtg
     7981 aattgcgtca gataaaaggc ataaccgaaa acatctatca gcggcttatc ccgtatgtct
     8041 gcgttctccc gacctcggaa cttagcatca atcttaatat gctaacggag aacgatattc
     8101 cgctcttcag agcattattc ctcaataaca tcacggatgc tgacgctcgg gtcttattac
     8161 aaaaaaggcc cagggaaggc tggctaacca cagatgcatt tctttactgg gcgcagcagg
     8221 atttctccgg cgtgaagccc ctggttgctc aggtgaaagg gcatctcttt ccctatagcc
     8281 gctattttac gctgagtacg gaaagtatca gcgacgaaca atcccaggga tggcaaagcc
     8341 atattttttt caaccgtaaa cagcagagcg cccaaatcta tcggcgtacg ctgcaactct
     8401 actaatcata aggatcgtga tgcctgaatc gttgatggta atacgttctt tctcgacgct
     8461 gcgtaagcat tgggaatgga tgacgttctc cgcagatagc gtatcttcgg tacatacgct
     8521 cacagacgat cttccgctgg ggtcgctggc cgatcagccc ggtgccggaa atgttcacct
     8581 tttgatccca cctgagggtc ttttatatcg ttccctcacg ctgcccaacg ccaaatacaa
     8641 actcaccgcg caaacattac agtggttggc ggaggagaca ttacccgacg ccagccaaaa
     8701 ttggcactgg acggttgtcg ataaacaaaa cgaaagtgtc gaggtgatag gcattcagtc
     8761 ggagaaactc agtcgttatc ttgagcgttt acatactgcc ggactcaacg tgacgcgggt
     8821 tttgccagat ggctgctatc ttccctggga agtagatagc tggactctgg ttaaccagca
     8881 aacaagctgg cttattcgca gtgccgcaca tgccttcaac gaactggatg aacactggtt
     8941 acagcatctt gctaaccagt ttccgcctga gaatatgcgt tgttatggtg tagcgcctca
     9001 cggcgttgca gcggccaatc cacttatcca gcatcctgaa ataccatcac tgagtttgta
     9061 ttctgccgat attgcattcc agcgctatga catgctgcat ggtgtttttc gtaaacagaa
     9121 aactgtaggc aaatcgggaa aatggctcac ccgcctggca gtaagctgtc tcgttctcgc
     9181 cattctttct tttgttggca gccggggcat cgcgctctgg caaacgctta agattgaaga
     9241 tcaacttcag caacaacagc aagaaacctg gcaacgttat ttcccgcaga tcaaacacac
     9301 ccacaacttt cgtttttact ttaagcagca actcgctcag caatatcctg aagctgtacc
     9361 gttgctctat catttacaaa cacttctgct tgaacactct gaactgcagt taatggaggc
     9421 gaactatagc cagaggcaaa agtcgctgac cttaaaaatg agtgctaaga gtgaagccaa
     9481 tatcgatcgt ttctgtgagt taacacagtc ctggcttccg atggaaaaaa cagaaaaaga
     9541 tccggtcagt ggtgtatgga cagtaaggaa ctcagggaaa tgattaaatc atggtgggca
     9601 gaaaaatcca catcggaaaa acagatcatt gcggcactgg cggttctctc gctcggcgtt
     9661 ttttgttggc ttgcggtgat aaaaccgata gatacctaca ttgaagagca tcagtcccac
     9721 gcgcaaaaaa ttaagaagga catcaaatgg atgcaggatc aagcgagcac ccatggttta
     9781 ctcggtcatc cagcgcttac gcagcccatc aaaaatatcc ttctcgaaga agcaaaacgt
     9841 gagaatttga ctatcacgct ggaaaacggt ccggacaata ctctgacaat taatcctgtc
     9901 acagctcccc tcgaaaacgt ctcccgctgg ctcactacgg cacagataac atacggtatt
     9961 gttattgaag accttcagtt tactcttgcc ggaaacgaag agatcaccct caagcatttg
    10021 tccttcaggg agcaacaata atgacaatgt tactgccgct cttcattctg gttggtttta
    10081 ttgcaggtta ttttgttaat gccatggcct atcacctctc gcctttggag gataaaacgg
    10141 cgttaacgtt tcgccaggta ttggttcatt tctggcaaaa aaaatatgcc tggcatgata
    10201 cagtgcccct gatactttgc gttgctgctg ctatcgcctg cgccctggca cctttcacgc
    10261 ccatcgtgac tggcgcactc tttctctatt tctgtttcgc actcacgctc agtgttattg
    10321 attttcgcac tcagctcctg cccgacaaac tcaccttacc gctgctctgg cttggtattt
    10381 aatgcgcagt ctggattaat tgatttacat gatgcggttt acggcgcggt cgctggctat
    10441 ggggtgctgt ggtgtgttta ctggggcgtc tggttagttt gtcacaaaga gggattgggc
    10501 tacggtgatt tcaagctact ggccgctgca ggcgcgtggt gtggctggca aacgttgcca
    10561 atgatactgc tgattgcctc gctgggtggc attggttacg ccatcgtttc acaacttctg
    10621 caacgccgga ctataaccac tatcgcattc ggcccgtggc ttgcgctcgg cagcatgata
    10681 aacctgggat atctggcctg gatctcttat taaccgggag ggttctccct cccgacacgg
    10741 ctcaaccttc ttcgcgaatc tgtgcttgca gataattttg cagtcccatc ttctgaatca
    10801 gatcaagttc cgtttccagc cagtcgatat ggccttcttc atcgcgcaaa atttctatca
    10861 tcatatcgcg gctgacgtaa tcatgaacgc tatcggcata accaattgcc tcacgcaaat
    10921 tcttcgcgcc atccagctca agtgccagat cagaacgcag catttcctca acatcttcac
    10981 caatgttcag tttgcccagg tcctgtaagt ttggaagacc ttccagaaaa agaatgcgct
    11041 ctatataacg atcggcgtgt ttcatctcat caatggattc atgatactcc acatcattga
    11101 gacgtttgag accccagttt ttaaacatcc gggcatgaag aaagtactga ttgattgcga
    11161 caagctcatt tcccaacagt ttgttgagat aatttataac tttagtatca cctttcattt
    11221 tttgactcct tcgcttccac tctttgaagc gtagaacggc ttacgagtaa gtcaaaaaac
    11281 acactccgtt tatgcggact ccttaaactc cggcagttgc attaattcat cctccatcac
    11341 ttcacgcgcg gcccggacac atttaccgca ctgattgccg accggaatga atttttttaa
    11401 ttgctggaac gagtgggggg aaaactggcg cacagcctga cgaatttttt tatcgctgat
    11461 accattacaa agacaaacgt acatagagac tcccgtatac tttcttcaaa agtaaatgaa
    11521 aatagttctt atttcaattg caggaagact cttttttaag caaagaatag aaatatgaat
    11581 aaaaataatg
//
LOCUS       DAPOXO010000124        11375 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.124, whole genome shotgun sequence.
ACCESSION   DAPOXO010000124 DAPOXO010000000
VERSION     DAPOXO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11375
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.124"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            204..563
                     /locus_tag="ROH59_004511"
     CDS             204..563
                     /locus_tag="ROH59_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1889 family protein"
                     /protein_id="HDX4806909.1"
                     /translation="MQIKVIYSLIDNMVNFKDKNMPAVIDKALDFIGAMDVSAPTPSS
                     MNESTAKGIFKYLKELGVPASAADITARADQEGWNPGFTEKMVGWAKKMESGERSVIK
                     NPEYFSTYMQEELKALV"
     gene            complement(683..862)
                     /locus_tag="ROH59_004512"
     CDS             complement(683..862)
                     /locus_tag="ROH59_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HDX4806910.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            936..2297
                     /gene="pabB"
                     /locus_tag="ROH59_004513"
     CDS             936..2297
                     /gene="pabB"
                     /locus_tag="ROH59_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HDX4806911.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSHLSHLPWAMLLHSGYADHPYS
                     RFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPAHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALVVDHQRQTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQAAILSLSPERFILCDNGEIQTRPIKGT
                     LPRLPDLLEDSKQAEKLANSTKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTTINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQ
                     LEK"
     gene            2301..2879
                     /locus_tag="ROH59_004514"
     CDS             2301..2879
                     /locus_tag="ROH59_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDX4806912.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEGEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            3063..4427
                     /gene="sdaA"
                     /locus_tag="ROH59_004515"
     CDS             3063..4427
                     /gene="sdaA"
                     /locus_tag="ROH59_004515"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDX4806913.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPFKSATELLAYCNETGFSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            4558..6156
                     /locus_tag="ROH59_004516"
     CDS             4558..6156
                     /locus_tag="ROH59_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDX4806914.1"
                     /translation="MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQ
                     RVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCSVAHLPLRKQAAKLQTVRSIGLV
                     QDGTLYCSSIFGYRNVPVVDILAELPAPQPLLRLTTDRALIKGSPVLIQWTPAAGSSN
                     AGVMEMINIDLLTAMLLEPQLPQISSASLTVDSRHLLYGNGLVDSLPQPENNENYQVS
                     SQRFPFTINVNGPGATALAWHYLPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLG
                     LAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFIPIAEEHHLIVPLTR
                     YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITE
                     RDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSD
                     AVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRSHGVHILQGYLYAQPMPLRDFP
                     KWLAGSQPPPARHNGHITPVMPLR"
     gene            complement(6160..7716)
                     /gene="yoaE"
                     /locus_tag="ROH59_004517"
     CDS             complement(6160..7716)
                     /gene="yoaE"
                     /locus_tag="ROH59_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HDX4806915.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            8180..9151
                     /gene="manX"
                     /locus_tag="ROH59_004518"
     CDS             8180..9151
                     /gene="manX"
                     /locus_tag="ROH59_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDX4806916.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPIEKAAPAPAAAAPKVAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            9214..10014
                     /gene="manY"
                     /locus_tag="ROH59_004519"
     CDS             9214..10014
                     /gene="manY"
                     /locus_tag="ROH59_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDX4806917.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            10027..10878
                     /gene="manZ"
                     /locus_tag="ROH59_004520"
     CDS             10027..10878
                     /gene="manZ"
                     /locus_tag="ROH59_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HDX4806918.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            10933..>11375
                     /locus_tag="ROH59_004521"
     CDS             10933..>11375
                     /locus_tag="ROH59_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HDX4806919.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLL"
BASE COUNT         2785 a         2877 c         2853 g         2860 t
ORIGIN      
        1 taaacataat catgccgtta tgttcgccct tcgattagca tctctggttt tctttcttac
       61 ctgaacaatc tggttatagc gtgaggactg accattaatt ttctccatct tactggataa
      121 cacaccatga gctgctacct ttaaaacacc tgaatgtcaa taggttaact cgtgccatat
      181 cgttataatc cctttgatat tagatacaaa ttaaggtcat atatagcctt atcgataaca
      241 tggttaattt taaggataag aatatgcctg ctgtaataga taaagccctg gatttcattg
      301 gtgccatgga tgtatcagcg ccaacaccaa gttcgatgaa tgaaagtacg gcgaagggaa
      361 tctttaaata tttaaaagaa ctgggagtac ccgcgagtgc cgctgatatt acggcgcgag
      421 ctgaccagga aggctggaac cctggtttca cggaaaaaat ggttggatgg gcaaaaaaaa
      481 tggagtctgg tgaacgctct gtgattaaaa atcctgaata cttttcaaca tatatgcagg
      541 aagaactaaa agcactggtt tgagttaaat tcacatcagc ataaatgggt caggacgctt
      601 ttaatcacat ataaaaagcg tcctttttct cacaatcaaa taatcatcgg cttctataac
      661 gaaagcgata cggattagtg tgttactcgt cttcatcctc aaaacgcgcc acgattcgct
      721 cgccggaatg gttggcacgc agctcttctg ccaccagcgc gattgcctgg ccgctgctca
      781 tcccttgtgc catcagttcc tggatccgct cgacggcttt ttgctgctgt tcatgggtga
      841 gtgaaggtaa acctgcaaac attgttaact cctgctaaat tgttggcgct aattatttca
      901 tgctacccgg cacatagcca gtagagtcag gactgatgaa gacgttatct cccgctgtga
      961 ttactttacc ctggcgtcag gacgccgctg aattttattt ctcccactta agccacctgc
     1021 cgtgggcgat gcttttacac tccggctatg ccgatcatcc gtatagccgc tttgatattg
     1081 tggtcgccga gccaatttgc actttaacca ctttcggtaa agaaaccgtt gttagtgaaa
     1141 gcgaaaaacg cacaacgacc actgatgacc cgctacaggt gctccagcag gtgctggatc
     1201 gtgcagacat tcgcccagcg cataacgaag atttgccatt tcagggcggc gcgctggggt
     1261 tgtttggcta cgatctgggc cgccgttttg agtcactgcc agaaattgcg gaacaagata
     1321 tcgttctgcc ggatatggca gtgggtatct acgactgggc gctggttgtc gaccaccagc
     1381 gtcaaacagt ttctttgctg agtcataatg atgtcaatgc ccgtcgggcc tggctggaaa
     1441 gccagcaatt ctccccgcag gaagatttca cactcacttc cgactggcaa tccaatatga
     1501 cccgcgaaca gtacggcgaa aaatttcgcc aggtacagga atatctgcac agcggtgatt
     1561 gctatcaggt gaatctcgcc cagcgttttc atgcgaccta ttctggcgat gaatggcagg
     1621 cattccttca gcttaatcag gccaaccgcg cgccgtttag cgctttttta cgtcttgaac
     1681 aggctgctat tttaagcctt tcaccagagc ggtttattct ttgtgataat ggtgaaatcc
     1741 agacccgccc gattaaaggc acgctaccac gcctgcccga tcttctggaa gatagcaaac
     1801 aagcagaaaa actggcgaac tcaacgaaag atcgtgccga aaatctgatg attgtcgatt
     1861 taatgcgtaa tgatatcggt cgtgttgccg tagcaggttc ggtaaaagta ccagagctgt
     1921 tcgtggtgga acccttccct gccgtgcatc atctggtcag caccataacg gcgcaactac
     1981 cagaacagtt acacgccagc gatctgctgc gcgcggcttt tcctggtggc tcaataaccg
     2041 gggctccgaa agtacgggct atggaaatta tcgacgaact ggaaccgcag cgacgcaatg
     2101 cctggtgcgg cagcattggc tatttgagct tttgcggcaa catggacacc agcattacta
     2161 tccgcacgct gactaccatt aacggacaaa tttactgctc tgcgggcggt ggaattgttg
     2221 ccgatagcca ggaagaagcg gaatatcagg aaacttttga taaagttaat aagatattac
     2281 gccaactgga gaagtaagac gtggaatacc gtagcctgac gcttgatgat tttttatcgc
     2341 gctttcaact tttgcgcccg caaattaacc gggaaacctt aaatcatcgt caggctgccg
     2401 tgttaatccc catcgtccgc cgaccgcaac cggggttgtt gctgactcag cgttcgattc
     2461 atctgcgtaa acacgctgga caagtggcat tccctggagg cgcagtcgat gacacggacg
     2521 catcagttat cgccgctgcg ctgcgcgaag ctgaagaaga ggtcgctata ccgccttccg
     2581 ccgttgaggt tatcggcgtg ctgccgcccg tcgatagcgt cactggctac caggtaaccc
     2641 cagtggtcgg cattatcccg cccgatctgc cgtatcgcgc cagtgaaggt gaagtctccg
     2701 ccgtctttga aatgccgctc gcccaggcat tacatctggg tcgttatcat cctttagata
     2761 tctaccgccg tggcgattca catcgggtat ggctgtcctg gtacgaacag tattttgtat
     2821 ggggaatgac cgcaggcata attcgtgagc tggcgctgca aattggtgtg aaaccctgac
     2881 tatacttatc tttacatcta caaaacacta cttgagacaa tcatcgcaat attagttaaa
     2941 tcgcggtttt tgattagttt aattcatgtg aatagttaag ccagtcgccg cgttccctct
     3001 tacactatgc gctgttatta gttcgttact ggaagtccag tcaccttgtc aggagtatta
     3061 tcgtgattag tctattcgac atgtttaagg tggggattgg tccctcatct tcccataccg
     3121 tagggcctat gaaggcgggt aaacagttcg tcgatgatct ggtcgaaaaa ggcttactgg
     3181 atagcgttac tcgcgttgcc gtggacgttt atggttcact gtcgctgacg ggtaaaggcc
     3241 accacaccga tatcgccatt attatgggtc ttgcaggtaa cgaacctgcc accgtggata
     3301 tcgacagtat tcccggtttt attcgcgacg tagaagagcg cgaacgtctg ctgctggcac
     3361 agggacggca tgaagtggat ttcccgcgcg acaacgggat gcgttttcat aacggtaacc
     3421 tgccgctgca tgaaaacggt atgcaaatcc acgcctataa cggcgatgaa gtcgtctaca
     3481 gcaaaactta ttattccatc ggcggcggtt ttatcgtcga tgaagaacac tttggtcagg
     3541 atgctgccaa cgaagtgagc gtgccgtatc cgttcaaatc tgccaccgaa ctgctcgcgt
     3601 actgtaatga aaccggcttt tcgctgtctg gtctcgctat gcaaaacgaa ctggcgctgc
     3661 acagcaagaa agagatcgac gagtatttcg cgcatgtctg gcaaaccatg caggcatgta
     3721 tcgatcgcgg gatgaatacc gaaggcgtac tgccaggccc gttgcgcgtg ccacgtcgtg
     3781 cgtcggccct gcgccggatg ctggtttcca gcgataaact gtctaacgat ccgatgaatg
     3841 tcattgactg ggtaaacatg tttgcgctgg cagttaacga agaaaacgcc gccggtggcc
     3901 gtgtggtaac tgcgccaact aacggtgcct gcggtatcgt tccggcagtg ctggcttact
     3961 atgaccactt tattgaatca gttagcccag acatctatac ccgttacttt atggcagcgg
     4021 gcgcgattgg tgcactgtat aaaatgaacg cgtctatttc cggtgcggaa gtcggttgcc
     4081 agggcgaagt aggtgttgcc tgttcaatgg ctgctgcggg ccttgccgag ctgttgggcg
     4141 gtagcccgga acaggtttgt gtggcagcgg aaattggcat ggaacacaac ctcggtctga
     4201 cctgcgaccc cgttgcaggg caagttcagg tgccgtgcat tgaacgtaat gccattgcct
     4261 ctgtgaaggc gattaacgcc gcacggatgg ctctgcgccg caccagtgca ccgcgcgtct
     4321 cgctggataa ggtcatcgaa acgatgtacg aaaccggtaa ggacatgaac gctaaatacc
     4381 gcgaaacctc acgcggtggt ctggcaatca aagtccagtg tgactaatac ttcttattcg
     4441 cccatctgca acggatgggc gaatttattc ccgctttctc gtctgctgta attttcccca
     4501 ctacacttcc actgttgcgt caggcgtttg tcgccatacg cttacagggt ggcccgcatg
     4561 caaaaagcac aacggatcat taaaacctat cgccgtaatc gaatgattgt ttgtacgatt
     4621 tgcgcactcg ttacgctcgc ttcgaccctg agcgtgcgat ttatttcaca gcgtaactta
     4681 aatcaacaac gggtagtaca attcgccaat cacgctgtag aggaattaga taaagtactg
     4741 cttcccctac aggcaggtag cgaagtcttg cttccgctga ttggtctgcc ctgctctgtc
     4801 gcccatttgc cattacgtaa acaggcggca aaactccaaa ctgtgcgatc cattggcctg
     4861 gtgcaagacg gcacacttta ttgctccagc atttttggtt atcgcaatgt gcccgtcgtg
     4921 gacattctgg ctgaacttcc tgcaccgcaa ccacttttac gactgacgac cgaccgtgcc
     4981 ctgataaaag gcagtccggt tttgattcaa tggacgcctg cagcgggcag tagcaatgct
     5041 ggggtcatgg agatgattaa catcgactta ctgacggcaa tgctccttga accacaactg
     5101 ccgcaaatca gtagcgccag cctgacggtg gacagtcggc atttgctcta tggtaatggg
     5161 ctggtagatt cccttccgca acctgaaaac aatgaaaact atcaggtttc ttcgcaacgc
     5221 tttcctttta ccattaacgt taatggcccg ggggctacgg cgctggcatg gcactatctt
     5281 ccaacacaat taccgctggc ggtgctgcta agtttactgg tgggctacat cgcctggctg
     5341 gcgaccgctt accgaatgag cttttcccgc gagatcaatc tgggcctggc gcaacatgag
     5401 ttcgaattgt tctgtcagcc tttgcttaat gcgcgcagcc agcaatgtat tggtgtagag
     5461 attttgctgc gctggaacaa tccgcgtcag ggctggattt caccggatgt gtttattcct
     5521 atcgcggaag aacatcattt aattgtgcca ctgacccgct atgtgatggc agaaaccatt
     5581 cgtcagcgcc atgttttccc aatgagtagt cagtttcatg ttggcattaa cgtcgcaccc
     5641 agccattttc gccgtggtgt gctgataaaa gatctcaatc agtactggtt tagcgctcac
     5701 ccgattcagc aactgatcct cgaaatcacc gaacgcgatg ccttactgga tgttgattac
     5761 cggattgccc gcgagctgca tcgtaaaaac gtcaaactgg cgattgatga cttcggcacc
     5821 ggcaacagtt cattttcctg gcttgaaaca ttacgtcctg acgtgctgaa aattgataag
     5881 tcatttaccg cagctatagg ttctgacgcg gttaactcga cggtgaccga tatcatcatc
     5941 gcactggggc aaagactgaa tattgaactg gtggcggagg gcgtagaaac gcaagaacag
     6001 gcgaagtatt tgcgcagtca tggcgtgcat attttgcaag ggtatttgta cgcacagccg
     6061 atgccgctac gtgattttcc caaatggctg gcgggcagcc aaccgccgcc cgcccggcat
     6121 aatggacata tcacgcccgt tatgccgtta cgttaacgct tactcatctt catcgtgcgc
     6181 cggttgctct ttaacaatgc gaaccagatc aacacgataa tcattggctt caatgatggt
     6241 gatatgcagt ggacctacat caatcacatc gcccacacgg ggaatgtgac catttgccga
     6301 gatcacgagg cccgcgaccg tcgcgatatc atcgtcatcg gcaaggtgct caacatcaag
     6361 cgcctgctgc aaggcatgca aatctgtacc gccttttacc agccagccgt caccgtcggt
     6421 aatgatttcc ggcgtttcgt cagcgtccgg gaattcaccc gcaatggctt ccagcacatc
     6481 cagcggcgtg accagacctt gtaccacacc aaactcgttg gtcacgataa caaagctccc
     6541 gcgagcacga cgcagcacgc ccagcaggtt gatcggatcg agggtttccg ggacgataat
     6601 cgccggagac gccgaagcta tcgccgccac atcaactccc tcttccagcg ccaccagcag
     6661 ttctttagca cgtacgatgc cgataatttc atccagttca ccgcgacata ccgggaacaa
     6721 actgtgcggt gaggagagca gttgctcgcg gatttcatcg accccgagat tagcatcaac
     6781 ccagcttatt tcaccgcgcg gcgtcatgat cccgcgcaga gaacgcgacg ccagcgtcag
     6841 tacgccgtta atcatgtaac gttcttcttc ggcaaacgca ccttccggga tcggcatcgg
     6901 catcgggtta tcggcatcgt gctgaacatt ggcctgacgt ttcccgccca tcaaacgcag
     6961 gatggcatcg gcagtacgcg ctcgcagcgg caaagtcgac tggtgacgaa taaagttgcg
     7021 acgcgcaatc tggttaaaca cttcgatgat gatcgagaag ccaatcgcgg catacaggta
     7081 acctttcgga atgtggaaac cgaaaccttc tgccaccaga ctcagaccaa tcattaacag
     7141 gaagctcaga cagagcacca ccaccgtggg gtgctggtta acaaatcgcg tcagcggttt
     7201 cgatgccagc agcataaccg ccatcgcaat cactaccgcc gccatcatca ccggcaaatg
     7261 gttaaccatc cctactgcag taattaccgc atccaacgaa aagacggcgt caaggatgac
     7321 aatctgtgtg acgaccaccc agaaactggc gtagccttta ccgtggccgg aatcatgatc
     7381 gcggttttcc agccgttcat gcagttcggt tgttgctttg aacagcaaga atatgccccc
     7441 gaacaacata atcaggtcgc gtccggagaa ggagaaatcc atgacggtaa atagcggttt
     7501 ggtcagcgtg accatccatg aaatcagcga cagcagcccc agacgcataa tcagcgccag
     7561 tgataatccc agcaaacgcg ctttatcgcg ttgttttggc ggcagtttgt cagcaagaat
     7621 ggcgatgaag accaggttat cgatacccag cacaatttcg agaacaacaa gcgtgagtag
     7681 ccccgcccaa atcgaggggt ccattaagaa ttccatgaca agctcctgct taaggaatag
     7741 ctattcgacg ccagaaataa tgcaggcgta acgacaaaat gcaaacgaaa ggtgcggcat
     7801 aaagtgccag aaagacaggc gttaaaaggc ctgatgctga aatgacgtcg gtgacgatcc
     7861 atactgcggg ctactgccct atactccatg gttgttaaac aggagttaaa catatcagag
     7921 acgcctctga tttggcaaag atttaccttc ctttgcaaac gaatgtgaca aggatatttt
     7981 acctttcgaa atttctgcta atcgaaagtt aaattacgga tcttcatcac ataaaataat
     8041 tttttcgata tctaaaataa atcgcgaaac gcagggggtt tttggttgta gcccttatct
     8101 gaatcgattc gattgtggac gacgattcaa aaatacatct ggcacgttga ggtgttaacg
     8161 ataataaagg aggtagcaag tgaccattgc tattgttata ggcacacatg gttgggctgc
     8221 agagcagttg cttaaaacgg cagaaatgct gttaggcgag caggaaaacg tcggctggat
     8281 cgatttcgtt ccaggtgaaa atgccgaaac gctgattgaa aagtacaacg ctcagttggc
     8341 aaaactcgac accactaaag gcgtgctgtt tctcgttgat acatggggag gcagcccatt
     8401 caatgctgcc agccgcattg tcgtcgacaa agagcattat gaagtcattg caggcgttaa
     8461 cattccaatg ctcgtggaaa cgttaatggc ccgagatgat gaccctagct ttgatgaact
     8521 ggtggcactg gcagtagaaa caggccgtga aggcgtgaaa gcactgaaag ccaaaccgat
     8581 tgaaaaagcc gcgccagcac ccgctgccgc agcacccaaa gtggctccaa ctccggcaaa
     8641 accaatggga ccgaacgact acatggttat tggccttgcg cgtatcgacg accgtctgat
     8701 tcacggtcag gtcgccaccc gctggaccaa agaaaccaat gtctcccgta ttattgttgt
     8761 tagtgatgaa gtggctgcgg ataccgttcg taagacactg ctcacccagg ttgcacctcc
     8821 gggcgtaaca gcacacgtag ttgatgttgc caaaatgatt cgcgtctaca acaacccgaa
     8881 atatgctggc gaacgcgtaa tgctgttatt taccaaccca acagatgtag agcgtctcgt
     8941 tgaaggcggc gtgaaaatca cctctgttaa cgtcggtggt atggcattcc gtcagggtaa
     9001 aacccaggtg aataacgcgg tttcggttga tgaaaaagat atcgaggcgt tcaagaaact
     9061 gaatgcgcgc ggtattgagc tggaagtccg taaggtttcc accgatccga aactgaaaat
     9121 gatggatctg atcagcaaaa tcgataagta acgtattgtg ttgattatca ctcagttttc
     9181 acacttaagt cttacgtaaa caggagaagt acaatggaga ttaccactct tcaaattgtg
     9241 ctggtattta tcgtagcctg tatcgcaggt atgggatcaa tcctcgatga atttcagttt
     9301 caccgtccgc taatcgcgtg taccctggtg ggtatcgttc ttggcgatat gaaaaccggt
     9361 attattatcg gtggtacgct ggaaatgatc gcgctgggct ggatgaacat cggtgctgcc
     9421 gttgcgcctg acgccgctct ggcttccatc atttctacta ttctggttat cgcaggtcat
     9481 cagagcattg gtgcaggtat cgcactggca atccctctgg ccgctgcggg ccaggtactg
     9541 accatcatcg ttcgtactat caccgttgct ttccagcacg ctgcggataa ggctgctgat
     9601 aacggcaacc tgacagcgat ttcctggatc cacgtttctt ctctgttcct gcaagcaatg
     9661 cgtgtggcta ttccggccgt catcgttgcg ctgtctgttg gtaccagcga agtccagaac
     9721 atgctgaatg cgattccgga agtggtgacc aatggtctga atatcgccgg tggcatgatc
     9781 gtggtggttg gttatgcgat ggttatcaac atgatgcgtg ctggctacct gatgccgttc
     9841 ttctacctcg gcttcgtaac cgcagcattc accaacttta acctggttgc tctgggtgtg
     9901 attggtactg ttatggcagt gctctacatc caacttagcc cgaaatacaa ccgcgtagcc
     9961 ggtgcgcctg ctcaggctgc tggtaacaac gatctcgata acgaactgga ctaacaggtg
    10021 agcgaaatgg ttgatacaac tcaaactacc accgagaaaa aactcactca aagtgatatt
    10081 cgtggcgtct tcctgcgttc taacctcttt cagggttcat ggaacttcga acgtatgcag
    10141 gcactgggtt tctgcttctc tatggtaccg gcaattcgtc gcctctaccc tgagaacaac
    10201 gaagctcgta aacaagctat tcgccgtcac ctggagttct ttaacaccca gccattcgtg
    10261 gctgcgccga ttctcggcgt aaccctggca ctggaagaac agcgtgctaa tggcgcagag
    10321 atcgatgacg gtgctatcaa cggtatcaaa gtcggtttga tggggccgct ggctggtgta
    10381 ggcgacccga tcttctgggg aacggtacgt ccggtatttg cagcgctggg ggctggtatc
    10441 gcgatgagcg gcagcctgtt aggtccgctg ctgttcttca tcctgtttaa cctggtgcgt
    10501 ctggcaaccc gttactacgg cgtagcgtat ggttactcca aaggtatcga tatcgttaaa
    10561 gatatgggtg gtggcttcct gcaaaaactg acggaagggg cgtctatcct cggcctgttt
    10621 gtcatggggg cattggttaa taagtggaca catgtcaaca tcccgctggt ggtctctcgc
    10681 attactgacc agacgggcaa agaacacgtt accactgtcc agactattct ggaccagtta
    10741 atgccaggcc tggtaccact gctgctgacc tttgcttgta tgtggctgtt gcgcaaaaaa
    10801 gttaacccgc tgtggatcat cgttggcttc ttcgtcatcg gtatcgctgg ttacgcttgc
    10861 ggcctgctgg gactgtaaga ctgttgtaca ctaccggggc cttttggccc cgttttttta
    10921 tctggaggat taatgacaat cacggacctg gtactgattc ttttcatcgc cgcacttctg
    10981 gccttcgcga tctacgatca gttcatcatg ccccgccgta acggccccac cctgctggca
    11041 attcctttgc tccggcgtgg tcgcatcgat agcgttatct tcgtcggatt gattgtcatt
    11101 cttatctata acaacgtcac gaatcatggc gcgcttataa caacatggtt attaagtgca
    11161 ctggctctga tgggttttta tatattctgg attcgcgttc cgaagatcat ctttaaacaa
    11221 aaaggttttt tcttcgccaa tgtctggatt gaatatagcc gaatcaaagc gatgaacttg
    11281 tcggaagatg gcgtgttggt gatgcaatta gaacagcgtc ggctgttaat ccgcgttcga
    11341 aatatcgacg atttggaaaa aatttataag cttct
//
LOCUS       DAPOXO010000125        11357 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.125, whole genome shotgun sequence.
ACCESSION   DAPOXO010000125 DAPOXO010000000
VERSION     DAPOXO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11357
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.125"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(414..899)
                     /gene="sixA"
                     /locus_tag="ROH59_004522"
     CDS             complement(414..899)
                     /gene="sixA"
                     /locus_tag="ROH59_004522"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HDX4806920.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTHGCDESRLMANWLKGQKVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVGAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGKGQFNWQMSPCNLKMAKA
                     I"
     gene            complement(1102..3246)
                     /gene="fadJ"
                     /locus_tag="ROH59_004523"
     CDS             complement(1102..3246)
                     /gene="fadJ"
                     /locus_tag="ROH59_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HDX4806921.1"
                     /translation="MEMASAFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEVLARQGQQLMAEIHALPI
                     PVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQAVKLGLVDDVVPHSILLEAAVELAKQDRPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRNIFFASTDVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLP
                     VRIKDINPQGINHALKFSWDQLEGKVRRRHLKASERDKQLALISGTTDYCGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNCATHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSP
                     VEKMPLVEIIPHASTSAQTIATTVKLAKKQGKMPIVVRDKAGFYVNRILAPYINEAIR
                     MLTEGERIEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIMPVLEAAYGERFSASANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGVQGQGRLSAPQVAERCVM
                     LMLNEAVRCLDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCDRLVEMSERGESFWKTTATDLQ"
     gene            complement(3246..4556)
                     /gene="fadI"
                     /locus_tag="ROH59_004524"
     CDS             complement(3246..4556)
                     /gene="fadI"
                     /locus_tag="ROH59_004524"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HDX4806922.1"
                     /translation="MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARTEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     EGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     GDLTLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDESKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            complement(4737..5021)
                     /locus_tag="ROH59_004525"
     CDS             complement(4737..5021)
                     /locus_tag="ROH59_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HDX4806923.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTL
                     AALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            5393..6733
                     /gene="fadL"
                     /locus_tag="ROH59_004526"
     CDS             5393..6733
                     /gene="fadL"
                     /locus_tag="ROH59_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416846.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HDX4806924.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVDITGHSNLTGQSANAKNIAPT
                     AWVPNLHFVAPINDQFGWGASITSNYGLATEFTDNYAAGIYGGKTDLQTINLNLSGAY
                     RLNNSWSFGLGFDAVYAKAKIERYAGSLGPLLSQQLIAQGVPASLTNGINTPDSQIAH
                     LKGDEWGFGWNAGILYELDKDNRWGLTYRSEVKIDFDGDYKSSINPNLNNILGNMGLP
                     YGTMGATQNGSLTLNLPEMWEISGYNRVAPQWAIHYSMAYTSWSQFQELKAKGDSGQT
                     LFYKDEGFRDAYRIALGTTYYYDKNWTFRTGIAYDDSPVPADKRSISIPDQDRLWLSA
                     GLTYAFNEDASIDVGASYMHGQKVKFTEGEGAAAYSFESEGKAWLFGTNFNYAF"
     gene            complement(6795..7550)
                     /gene="mlaA"
                     /locus_tag="ROH59_004527"
     CDS             complement(6795..7550)
                     /gene="mlaA"
                     /locus_tag="ROH59_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HDX4806925.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
                     DGGDMADSLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
     gene            7844..8776
                     /locus_tag="ROH59_004528"
     CDS             7844..8776
                     /locus_tag="ROH59_004528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDX4806926.1"
                     /translation="MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGIVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA"
     gene            8852..8926
                     /locus_tag="ROH59_004529"
     tRNA            8852..8926
                     /locus_tag="ROH59_004529"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8885..8887,aa:Arg,seq:cct)
     gene            9087..10262
                     /locus_tag="ROH59_004530"
     CDS             9087..10262
                     /locus_tag="ROH59_004530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX4806927.1"
                     /translation="MLLSDIQIKRAKPKDKPYTLNDGMGLSLLIDTAGSKGWRFRYRF
                     AGKPKMISFGVYGDVSLAQARTKRDEARSMLANGINPSEARKADKIALQFAHENSFES
                     VAREWHSSKKATWSEGYAKEVLNCMEKDIFPFIGQRPIEQIEPLELLTVLQKIEKRGA
                     LEQTSKIRRRCGEVLRYAVATGRAKYNFAPDLAIALNKPKTQHFPFLTESELPEFVNA
                     LDNYQGSLVTKYATQLLMLTGVRTIELRAAEWAEFDLDNALWEIPKERMKKRRPHLVP
                     LSTQAINILKKLQEITGNYSLVFPGRNDVSKPMSEASINKVIKLLGYHGRLTGHGFRH
                     TMSTILHEHGFESAWIEMQLAHVDKNSIRGTYNHAQYIKDRQVMMEWYASLLNTTCY"
     gene            complement(10242..11192)
                     /locus_tag="ROH59_004531"
     CDS             complement(10242..11192)
                     /locus_tag="ROH59_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HDX4806928.1"
                     /translation="MYSPYLYARSTELLCLRDLVAKGVSLNGLLPILEPINVNTRNLL
                     TCLNVWNSDIIVILNPYQEDFSSHNNVLTLNQNLSSVLTNKNNIISGYLIQPNTTIND
                     INNWLNANLNRRVALLYDNPSLSNSDIQLLATNQLISYHVVLNNKMLPNQCALLPLSK
                     LIIISDNFRKLAKNADYNGPELFTHAHQFVGQNYLGFGDYTITGQVLDLGGGQPSAVA
                     AHLVFKNLQANTVWIRHFVSSNTQRGSSNVTAKFLDVSDQITNLVPQHPTQFGSNIGL
                     NYYYYNSQPTVRHFPGLPKNKQYQITHHICFMLDLIAGRI"
BASE COUNT         3108 a         2763 c         2582 g         2904 t
ORIGIN      
        1 ttatgttggt cttatctata aaaaaactca atttagtaat acttaaagac tttatgtaga
       61 ttttattaat taatacatcg gcaaaatact ttcaccactt tccaacaaaa aaacatgcga
      121 attatcaaca aaaaacaaac tatcataatc aacaaaaatg aattgcttat aaagcacact
      181 aaaaaattat aatgacctta ccattattta ttgctaaaat ttaatattaa ttaaatcaat
      241 aaatatatat tcaagacaca aaaccattat cttctttatt ttattacggg attcaataat
      301 gggaaaataa ctatcgagag ttgttaaata ttaacaacat ttagacaaaa aaagaatgat
      361 tgtatgacgg agaaactgcc cggtgtacgc gcacgtaacc gggcattgat tgcttaaatt
      421 gcttttgcca tcttcaaatt acaagggctc atctgccagt tgaattggcc ttttccgctt
      481 tcatcaagcg ttacgctggc aatcgctgac gtggtaaaca taggcggcgt ttcgcccgga
      541 cataactcgg caaccagata cccaactaac ggtaagtggg agatcaccag taccgaagca
      601 acaccttcat tggtcaacgc ctgcaaatag gcaccgacca gaccaacatc gccgcagggc
      661 gttaactccg gcagaacttc tgcactggaa ggcaggttca gacaatcccc tacttcttca
      721 agtgtttgct cggctcgcag gaacgggctc accagaacgc gttcgatttc cactttttga
      781 cctttcagcc agttcgccat caggcgagat tcgtcacaac catgagtggt cagaggacga
      841 accgaatcac tggcggcatc gagggctgcg tcgccgtgac gcatgataaa aacttgcata
      901 ttgcaccgct tttgttaacc agattcgccc gttttctttc atctgaaacc agagaaagaa
      961 aacggtggcc ggcattgtgc cttatccatt caccgaatga aacgctgttt tttacctcaa
     1021 tggcgtaagt atagtcaata tgcgtttaca ttttgagcaa cactccgcca ttcagcgcgg
     1081 attcatataa ctttgacctt cttattgcag gtcagttgca gttgttttcc aaaaactttc
     1141 cccacgctcg ctcatctcaa ctaaacgatc gcaaggggta aaacgggaac catactgcgt
     1201 ggccagtcgt tgcattattg caaccacttc gcctgcgccg agagaatcga tatagcggaa
     1261 cggtccaccg agaaatggcg gaaaaccaat gccaaatacc gcaccaatat ccccgtcacg
     1321 cacgctacgg ataacctgct cgtccagaca acgtactgct tcattcagca tcaacatcac
     1381 acaccgttca gcaacctgcg gtgcggagag tcgcccctgc ccttgtacgc caatgagcgg
     1441 gtaaatggcg ggatcgacct gttttttgct tttacgccct ttctgaccat aaagatagaa
     1501 accccgacca ttttttctgc ctttgcgatc gtcgttcaaa attgaagaaa caacatttgc
     1561 agacgcgcta aaacgttctc cataagcggc ttccagtaca ggcataattt tagtccctgt
     1621 gtcgattcct acctcatcca aaagttggat tgggcctacc ggaaaaccaa atttcactag
     1681 cgcggcatcg atatgctcaa tacgctcgcc ttcggtcaac atgcggatag cttcattgat
     1741 gtaaggcgct aagatgcgat tgacgtaaaa cccagctttg tcacgcacga caattggcat
     1801 tttgccctgt tttttcgcca gttttaccgt ggtggcgatg gtttgcgccg atgtactcgc
     1861 atgaggaata atctccacca gcggcatttt ttccaccgga ctgaagaaat gcaggccaat
     1921 aacttgctca ggtcgcgtgg cgtgagcggc gatatcgcca atcggtaaag atgacgtgtt
     1981 cgaagcaaag atggtatgag tagcgcaatt ttgctccact tccgccacca tctgttgttt
     2041 taattcgaga ttttcaaaca ccgcttcaat aatcagatcg cgatgggcaa agccgcaata
     2101 gtccgtcgtt ccggagatta atgccagctg tttgtcacgt tcgctggctt tgagatgacg
     2161 acggcgaact ttgccctcaa gctgatccca actgaacttc agcgcatgat ttatgccctg
     2221 cgggttgata tctttaattc tgaccggaag ccccgcttta caagcagtga cataagcaat
     2281 accgccgccc atcaagccac cacctagaat ccccacgctg tttaatggcg caggcggcgc
     2341 atcactgccg ggatcttttt tcacgtccgt actggcaaaa aagatattgc gcagcgcctg
     2401 cgattgcggc gtcatcgcca gttcaccaaa cgcccgagct tcggcgtcat agccactgct
     2461 ggtcccctgc gctaatcccg tttcgacaac ctccaggatg cgttctgtcg ccggatagtt
     2521 accttgcgtt ttgtgttctg ttttcttgcc gaccattttg aacagcagcg cacgacctaa
     2581 cggccccgcc agaatacgct cgcgaacagg tagagggcgt gaagatgggc gatcctgctt
     2641 tgccagctca acagcggctt ccagcaatat ggagtgcgga acgacgtcat ccaccaaccc
     2701 cagctttacc gcctgtttcg cccgaagttg ttttccggtg aggatcatct ctaatgctgt
     2761 gctgacacct atcaggcgcg gtaaacgctg ggtacctcct gaaccgggta acaatccaag
     2821 ttgtacttca ggcaaaccga gcaccgtttt aggatcgtca gtacaaacac gaccgtggca
     2881 cgccagcgcc aactccagcc cgccgcccag gcaagcgcca tgaatagccg cgataaccgg
     2941 aatgggcaaa gcatgaatct ccgccattaa ctgttgcccc tgccgcgcca gtacttccgc
     3001 ttcttgcgcc gttttgcagt tgccgatcat gttgatgtct gcgccagcaa tgaagttgtc
     3061 tggtttcgcg gagacaaaca ccacgccacg caactctttg ttttcacgga gttgcttaat
     3121 aatggcgcgt acctgcgagg caaattccgc cttcagggta ttcattttct cacccggtac
     3181 gtcgatggtg atgatagcaa tgttgtccag acgaacatta agagtaaacg ctgatgccat
     3241 ttccattatt ccgcctccag aaccattgct gcgccaagcc cacccgcagc acaggcggtc
     3301 actaaaccaa atccaccgcc acgacggcga agttcatgca atgtctgggt aatcatccgc
     3361 gcgccggtcg ctgcgaaggg atgcccgtaa gcaatcgaac cgccaagcac gttaaatttg
     3421 ctctcgtcca cttcgccagt ggcatgtgca cgccccagta cgtcgcgagc aaaacgttcg
     3481 ctacccagca actgaatatt ggccagcgtc tgggcggcaa aggcttcgtg catatcgatc
     3541 aatgtcagat cgcccatcgt caatccggca cgttccagcg ccagcggtgt tgaccaggct
     3601 ggaccgagca acatgtcctg ccagacatct atcgcagtaa atgcgtagct gcgcagatag
     3661 cccagcggta ccagccctaa ttctttcgcc cgggattcag tcatcaggat caccgctgcc
     3721 gcgccatcgg tcagcggcgt actgttcgcc gccgttaccg tcccgtgttt acgatcaaac
     3781 gccggacgca actttgcgta atcagcaaga gaggaattac cgcgaatatt gttgtcttcg
     3841 acaagcggtt gtttataagg agggataaag gcagtcatca cctcttcttt gagtttacct
     3901 tctgaccacg cctgagcggc acgctgatgc gaacggtgcg ccagtgcatc ttgctgttct
     3961 cgggtgatgc cgtaggtttt cgccatttgc tctgcggtgt cccccatccg caagccggta
     4021 gaatattctg ctaccgcagg cggtacgggc attaagtcgc gcaaacgcag gcgagagaag
     4081 agtttcaggc gctggctcat tgtgcgggct ttgttgacat caaccagtac gcgcgccagt
     4141 tttttactga cgccaattgg caatacggaa gaggaatctg ccccaccggc aatccccgct
     4201 cgaatagttc ccgccatcag gctttcggca acgttcgcaa ccgcctgaaa actggtggcg
     4261 caagcgcggc tgacgctgta agcatcagta tgcacattca ttccagtgcc aagaacaatt
     4321 tcacgggcaa tgttgggcgc ttccggcatt tgcacaacct gaccgaagac caattgttca
     4381 atcacttcag cggggatctc ggtgcgtgcc agcagttcgc ctaccaccat cttccctaaa
     4441 tcaaccgcgg gaatgccatg aaaagccgtc gcctgtcggg caaaaggcgt acgtaaaccg
     4501 ctaacaatgg cgatacgatc gccctggcgg gtaaccagcg gtaaaacctg acccataaca
     4561 ctcccctgta aaaaaataaa taaagtggtc tgacctgatc atagtcttaa ccattttttt
     4621 acatttagcc aagtggagaa aagggaaagt gggagctatg acacagagag aaaagaggag
     4681 gagaaaataa aacgcccctg tcagcagctg acaggggcgt atgtacccga gaggaattaa
     4741 cgcagaccca gctggaagat cagcatttca gcttcgcagg caaaagtgaa atcgatatcc
     4801 aggcgcacac cgtcagactc ttcagtgaaa gtcggggtga ttttgcacgg ttcggattcc
     4861 acgctacggg ctttttcagt cagcgccgcc agcgtttgtt ctgcttctgc gcggtttgca
     4921 aacacacggc tgtaagacgc ggtgcagtcg gagttgtcca taatggtgcc aacatccata
     4981 cagcagcaaa ccggggtttc atcagcacta catttactca tcgttgattt cctctgtatg
     5041 tgcacccaag gtgccagata aacgttgtgg atattttacg cttccggaaa gtgctgctcc
     5101 agttgttaat tctgcaaaat cggataagtg accgaaatca cacttaaaaa tgatctaaaa
     5161 caaaattcac ccgaatccat gagtgcgcca cctcccaatt ttgccagctg gatcgcgttt
     5221 cttagatcat atctgaaaaa agatagaaac atacttgcaa catcccagct ggtccgacct
     5281 atactctcgc cactggtctg atttctaaga tgtacctcag accctacact tcgcgctcct
     5341 gttacagcac gtaacatagt ttgtataaaa ataaatcatt gaggttatgg tcatgagcca
     5401 gaaaaccctg tttacaaagt ctgctctcgc agtcgcagtg gcacttatct ccacccaggc
     5461 ctggtcggca ggctttcagt taaacgaatt ttcttcctct ggcctgggcc gggcttattc
     5521 aggggaaggt gcaattgccg atgatgcagg taacgttagc cgtaaccccg cattgattac
     5581 catgtttgac cgcccgacat tttctgcggg tgcggtttat attgatccgg atgtagatat
     5641 taccggacat tctaatttaa ccggtcagag tgcaaatgct aaaaatatcg cgccgacagc
     5701 gtgggtacct aacctgcact ttgtcgcgcc tattaacgat cagtttggtt ggggagcgtc
     5761 aataacttcc aactatggcc tggctacgga atttaccgac aactacgctg ctggtatcta
     5821 tggcggtaaa accgatctgc aaacaatcaa ccttaacctt agcggggctt atcgccttaa
     5881 caatagctgg agttttggtc ttggttttga tgcagtttat gccaaggcaa aaattgagcg
     5941 ttacgccggt tcgctggggc cattgttgtc tcaacagttg attgcccagg gtgtacccgc
     6001 ttcattaacc aatggtatta atactccgga ctctcaaatt gctcatttga aaggtgacga
     6061 atggggcttt ggctggaacg cgggtattct ttatgaactg gataaagata accgttgggg
     6121 gctgacatat cgttcagaag ttaaaatcga cttcgatggg gattacaaaa gctccattaa
     6181 cccaaatctg aacaatattt tgggtaacat gggcttaccg tatggcacga tgggggcaac
     6241 ccaaaatgga tccttaacgc tgaacctgcc tgagatgtgg gagatttctg gttataaccg
     6301 tgttgcgccg cagtgggcaa ttcactacag catggcctat accagttgga gccagttcca
     6361 ggaattgaaa gcgaaaggcg atagtggtca gactctgttc tataaagatg aaggattccg
     6421 ggacgcgtat cgtatcgcgt tgggtacaac ctactattat gataaaaact ggaccttccg
     6481 taccggtatc gcttatgacg acagcccggt tccggcagat aaacgttcta tttccattcc
     6541 tgaccaggat cgtttgtggt taagtgctgg gttaacctac gcatttaatg aagatgcatc
     6601 cattgatgtt ggcgcatctt atatgcatgg tcagaaagtg aaattcaccg aaggtgaagg
     6661 agcggcagct tattccttcg agtctgaagg taaagcctgg ctgttcggta ctaactttaa
     6721 ctacgcgttc tgataacgcg ttagcttaat aagaaaaaag gtgagttttg cgactcacct
     6781 tttttgtttg tttcttattc agaatcgata tcttttaaat catcctgaat cgcttgcgcg
     6841 ttcggatttt cctgcggttt gagttcaccg ccattagcga tgaaatcatg acgctggaag
     6901 tacgcttcac gcaccataat ataaggatcg gaggactgac gcagcagacc gtcggaatcc
     6961 aacaactgcg cacgagtttc tatcccttca agcgtccatt tacccacaga catcggccag
     7021 gtcagccagg aaagaaccgg gtaaagacta tccgccatat caccaccgtc atcacgcagc
     7081 gtgaagctac cgtagaacgg taactgaacg tacggcccat aacccacacc ataatgacca
     7141 agcgtactac cgaagcggtg aggttcagtc cgttgcagtt tcgggttcgc catccctgca
     7201 acatcaataa agccgcccat tcccaaaatg gtattcagga aaaagcgggt aaagtggacc
     7261 atcccctgat aagggtcgcc ctgcaagaag tagttaacca tcaccgcagg ttcttcaagg
     7321 ttgccggtaa agttgctcaa accgttacgc gcaggttgcg gaacataatc acgccaggcg
     7381 acagcgaccg gtcgaacaat atacgggtct aatacattga agttgaagtt gtacatagtg
     7441 cggttaaacc cttctaacgg gtcagaacgc ccttgctgat ctgtaccgga actcgcacac
     7501 cccaccagaa gcgtagttcc cagagcaagc gccgacaggc gaagcttcat aaatgtctcc
     7561 ctgttttttt atggcttatg cagtttgcca tccatgacgg aacgataccg tatccgcctg
     7621 tttaggtgtg ggcgattgta acagcacgtc aactgatgtc cagacgccct gatttgctga
     7681 tttgatcata gcctggtaat cgccgccctg taggctactt gattcaatag aaacagaaaa
     7741 aggcaaacgc ggccttttct acattttcag agtaactccc gccagttgcg agcaaaaaag
     7801 ccgctacgct ttagctatac gtgctaattc aagagaagag accatggaca acgacaaaat
     7861 tgatcaacac agcgacgaaa ttgaagttga gagcgaagaa aaagagcgcg gtaaaaaaat
     7921 agaaatagat gaagaccgac tcccctcccg ggcgatggca attcatgagc atatccgcca
     7981 ggatggtgaa aaagagctgg aacgcgacgc aatggcgcta ctgtggtcag ccattgcggc
     8041 gggcctgtcg atgggcgctt cgttactggc aaaagggata tttcatgtcg aactggaagg
     8101 cgtgccgggc agcttcttgc tggagaatct cggttatacc tttggtttta ttatcgtcat
     8161 aatggcccgc cagcaattat ttaccgaaaa caccgtaact gcggtactac ccgtcatgca
     8221 aaaaccgaca atgagcaacg tcggcttact tatgcggtta tggggcatcg tgctgctggg
     8281 taatattctc gggacaggta ttgctgcgtg ggcatttgaa tatatgccta tcttcaatga
     8341 agaaactcgc gatgcatttg tcaaaatcgg catggatgtg atgaagaaca cccccagcga
     8401 gatgtttgcc aacgcgatta tttccggctg gctgatcgcc actatggtat ggatgtttcc
     8461 tgcagcgggt gcggcaaaga ttgtggtgat tatattgatg acctggctta ttgccctggg
     8521 tgacaccacc cacatcgttg tcggttctgt tgaaatcctc tatctggtgt ttaacggcac
     8581 gctgcactgg agcgatttca tctggccctt cgcactacct actttagcgg ggaacatctg
     8641 cggcggcacc tttatcttcg cgttaatgag tcatgcacag attcgtaacg acatgagcaa
     8701 caagcgcaaa gcagaagcac gtcaaaaagc agaacgtgcg gaaaacatta agaaaaatga
     8761 taaaaacccg gcataaatgg cgagggttta agcaatcgag cggctgtgta cttaccccgt
     8821 agtccattag cgggtatact catgccgcat tgtcctctta gttaaatgga tataacgagc
     8881 ccctcctaag ggctaattgc aggttcgatt cctgcagggg acaccatgaa cacttctcac
     8941 taagttcaat taattccata actcactgtt ttaactgata tcatctcctt atactcgtcc
     9001 agcaaagtac cattatttct aatggaatct atacatcttt gcgtataaca ttgtgtataa
     9061 ctgagttcga tcttttttct atacacatgc tgctatctga catccaaata aaaagagcaa
     9121 aaccgaagga caaaccctat acgcttaacg atggtatggg gctatcactc ctgatcgaca
     9181 cagcgggcag taaaggctgg cgttttcgct atcgctttgc aggtaagcct aagatgattt
     9241 cctttggcgt atatggcgat gtgtcgttgg cacaggcacg taccaaacgt gatgaagcgc
     9301 gttcgatgtt agccaacggg ataaacccaa gtgaagccag aaaagcagat aagattgctt
     9361 tgcagttcgc gcatgagaac agctttgagt ctgtggccag agaatggcac tcatcgaaaa
     9421 aagccacctg gtcagagggt tatgcaaaag aggttctcaa ttgtatggaa aaggatattt
     9481 ttccttttat cggccagcgc ccaattgagc agattgaacc attagaactg ctaaccgtcc
     9541 tgcaaaaaat agagaaaaga ggtgcgctag agcaaaccag taagatccgc cgccgctgtg
     9601 gtgaagtgct tcgttatgct gttgccactg gtagagcaaa gtataatttt gcacccgatt
     9661 tagctatcgc actcaacaaa cctaaaaccc aacacttccc gttcctgact gaaagcgagt
     9721 tgcccgagtt cgttaatgct ctggataact atcagggcag tttagttacc aaatacgcca
     9781 cgcagctgtt gatgctaaca ggcgtgcgaa caattgaact acgtgcagcg gaatgggctg
     9841 agtttgattt agataatgcc ttatgggaga tccccaaaga acggatgaag aaacgccgcc
     9901 cccatctggt tccgttatca actcaggcga tcaatatcct gaaaaagctg caagaaataa
     9961 cagggaatta cagcctcgtt ttccctggcc ggaatgacgt cagtaaacca atgagcgaag
    10021 ccagcatcaa caaagtgata aaactactgg gttatcacgg tcggttaacg ggtcacggtt
    10081 tcaggcatac catgagcacc atcttgcatg agcatgggtt tgaaagtgcc tggattgaaa
    10141 tgcagcttgc gcatgttgat aagaactcta ttcgaggtac ttacaatcat gcgcaatata
    10201 ttaaagatcg acaagtaatg atggaatggt acgctagctt attaaatacg acctgctatt
    10261 aaatccagca tgaaacaaat atggtgagta atttgatact gtttgttttt tggcaaccca
    10321 gggaaatgcc ttacagttgg ttgactattg taataataat agttaagacc aatgttgctg
    10381 ccaaactggg ttggatgttg gggaacaaga tttgtaattt gatctgaaac atctaaaaat
    10441 tttgcagtaa catttgaact tcctcgttgc gtgttgcttg atacaaaatg acgaatccaa
    10501 actgtattcg cttgtaaatt cttgaacacc aaatgtgcgg caacagcaga aggttgacca
    10561 cctccaagat ctagtacctg gccagtaatt gtataatcgc caaatcctaa gtaattttgt
    10621 cccacgaatt gatgtgcgtg cgtgaaaagt tccggcccat tataatcagc attttttgct
    10681 aactttctaa agttatcgct aataataatt aacttcgaca aaggaagaag agcgcactga
    10741 ttaggaagca ttttattatt taaaacaaca tgataactaa tcaattgatt tgtcgccaac
    10801 aactgaatat cagagttgga taatgatgga ttatcatata gaagtgcaac tcgtctattt
    10861 aagttagcat tcaaccaatt attaatatca ttaatcgttg tattgggctg aataagatat
    10921 ccagagatga tattattttt atttgttaat acacttgata aattttgatt taaagttaag
    10981 acgttattgt gtgaagaaaa atcttcctga taaggattaa ggataacaat tatatcagaa
    11041 ttccaaacat ttaaacatgt taataaattt ctcgtattga cgttaattgg ttctaaaatt
    11101 ggtagcagac catttaggct aactcccttc gcaacgaggt ccctaaggca taataactct
    11161 gtacttctcg catacaaata tgggctatac ataacttaca actcctgagg atatcaacaa
    11221 attttaattt ttacatccat caaattcatg atgaattctt tttgctttct tgataatggt
    11281 gttgcataac ctaaaacacg taaacatgct ggaagagaat aaatataatc caaaaaaact
    11341 ttatcgttac atctttt
//
LOCUS       DAPOXO010000126        11192 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPOXO010000126 DAPOXO010000000
VERSION     DAPOXO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11192
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.126"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(619..873)
                     /locus_tag="ROH59_004532"
     CDS             complement(619..873)
                     /locus_tag="ROH59_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="HDX4806929.1"
                     /translation="MPQQHPGRLQILVVDAHCKRRLFSTKTPTDPDELARRFCTPDNC
                     LVVVLRDNRFLFRLERAPGSHCRWHKGSSSRHQHLQDWLS"
     gene            complement(1045..1728)
                     /locus_tag="ROH59_004533"
     CDS             complement(1045..1728)
                     /locus_tag="ROH59_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraC"
                     /protein_id="HDX4806930.1"
                     /translation="MTTTEHPVRQLLWCALNALKTAQENHNITSETGLRHYLLEWLSG
                     ASRHPEFSSLPGEIMALKALTEKDRNIPIIGTLNTLFLSSATVGECPLFRFRAALGKL
                     QKAGWRIYVCPWPEMVFNESIERACSGKRHLLQLSRTEECFLPTGDMRAPVTLQLITP
                     LHRKTMQLLETAELIFSDEGFQVVRGYEHQFGIERRETLFHTLFIGLPSLPEDVWGAT
                     QEQTTITLH"
     gene            complement(1982..2515)
                     /locus_tag="ROH59_004534"
     CDS             complement(1982..2515)
                     /locus_tag="ROH59_004534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001303319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusG"
                     /protein_id="HDX4806931.1"
                     /translation="MNIEHLNNRNWYLAQYNTAGKNRESLFSWLNEQNVVPWTPLITR
                     KIRRADSRCCHRERIFAIFPGYFFILANFDIQPVSALRRHSAFIDFVKFGGEIKPVNK
                     DIVDGLMKIYPDPVLNPGAREELNAASSIWLTKAQYQYLLRMENTLQPESRISLLLEL
                     VSNAEHHGFMERLVNIP"
     gene            complement(2957..3244)
                     /locus_tag="ROH59_004535"
     CDS             complement(2957..3244)
                     /locus_tag="ROH59_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HDX4806932.1"
                     /translation="MSPQMIQKLPAITLLEGMFPELSTNQLKVCVFYAMGVPYDAIAQ
                     NCRLSPETVRTYLKRSLKNLNLEGYDALRSAVLMRTFVFMISNTAKENEKM"
     gene            complement(3162..3425)
                     /locus_tag="ROH59_004536"
     CDS             complement(3162..3425)
                     /locus_tag="ROH59_004536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HDX4806933.1"
                     /translation="MPYHKDRNLYFLSSSMVAQAGQALAWPVSDDAGIPTPVWAITNE
                     RRNSVIAFFVVIGDLCYVTSNDTETPGHHSVGRHVSRAINKPA"
     gene            4397..5428
                     /locus_tag="ROH59_004537"
     CDS             4397..5428
                     /locus_tag="ROH59_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDX4806934.1"
                     /translation="MAGLKNTPYNAVHWSQLAPEEQIRFWEDYEAGRATTFLVEPERK
                     RTKRRRGEHSTKPKCENPSWYRPELYKALSGQLGHAYNRLVKKDPVTGEQSLRMHMSL
                     HPFYVQKRTYAGRKYAFRPEKQRLLDAIWPVLVSFSDAGTHTVGMSVSRLAREISPKD
                     SKGKVIPELEVTVSRLSRLLAEQVRFGVLGVSEETLWDRETRQRLPRYVWITPAGWQM
                     LGVDMVKLHEQQQKRLRESEIRQQLIREGVLREDEDISVHAARKRWYLQRSQDALKHR
                     RAKAAASKRARRLKKLPADQQIHEMAEYLRKRLPPDEAYFCSDDHLKRLAIRELRQLE
                     LTLAAPPPH"
     gene            6124..6264
                     /locus_tag="ROH59_004538"
     CDS             6124..6264
                     /locus_tag="ROH59_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004031751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806935.1"
                     /translation="MAENGYGLAGLGMGKVKSISPYRLTPGFGGFTPVSYATTECRLP
                     CR"
     gene            complement(6497..7006)
                     /locus_tag="ROH59_004539"
     CDS             complement(6497..7006)
                     /locus_tag="ROH59_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806936.1"
                     /translation="MSKSGAEKIQFILNNHEQAYRRLKPVYTFLELASWISVVLLIIY
                     LSGKNHVLTAAFLCFAWTAFWVLFLLHYFPKVFSILDRQSLLNLMEATKDSPDVKQEL
                     LNRLFSGKRMTGRDEMDICRLLRKNEEEKIRQSELNIIRNFIDEQQLTNSDIPKKSTV
                     PNEDKKGIR"
     gene            complement(7062..7664)
                     /locus_tag="ROH59_004540"
     CDS             complement(7062..7664)
                     /locus_tag="ROH59_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proQ/FINO family protein"
                     /protein_id="HDX4806937.1"
                     /translation="MEKNQEERKIPVIVVKKRRTFSLPSLSEKTDIIESAFTEQAAES
                     APVGINSSAVETHIPEAPARKKKKKKRRFPRPSHWTREYTHECVEKIKILFPHLRAEG
                     GGFIPLKIGINNDISAFLAEHPETELTMDEWLCAVSCITSRRVYLQRTAVAGVPRYGL
                     DGHPKGQVSESEAQSAGRRLVTLEQKLLRMQAQQENISGQ"
     gene            8018..9364
                     /locus_tag="ROH59_004541"
     CDS             8018..9364
                     /locus_tag="ROH59_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806938.1"
                     /translation="MPMILVKKNPRGKVIRELSSEEETAVKTVCGLKKPATMAQHNLA
                     NDLLREMREYDAWLQCDCIPGDSPAMNFAALKNNTGTLYLSSFNHEHAPECPMYRQLS
                     GNEEETSFGASRHPVSTRINYRNFLPPDDSNSVIRLQTRSAYHNGERSSVRKKRPRLG
                     RLLLSLIEDAGLNKLDSLANPRIRTNYRECLDAIRQVTLQQEYIRGRSLSEIIHFRPG
                     MSERSQERLMETLENSERHWPARRKHMFFQIFMAQHICRDAVEIHWANGNIQVFRPVR
                     GISINGEAQGGIRPPYWVILAFCRSADGRIICSEGYAHALYQLTCPVPVDSKLERNTL
                     TALLNVASWLKRKPGTPELSLERPLFDTEVYVNGEKKYVLPDFIVTARAPDGKTARVV
                     IETMGYEDSDYCARKSRQHTGMKQIGVLHTDPPKWLDNDHPPFEKHMYGVFMHLRY"
     gene            complement(9863..10165)
                     /locus_tag="ROH59_004542"
     CDS             complement(9863..10165)
                     /locus_tag="ROH59_004542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806939.1"
                     /translation="MRNRANTSPRDEAAFINGGTAGLDNTKKSSDKSSVVSKAKPVSI
                     SFFEENLKDIDALITAEMVSGKGRVNRSDVVRAAVEALKTLSKTEVSRLIAEVKQR"
     gene            complement(10162..10788)
                     /locus_tag="ROH59_004543"
     CDS             complement(10162..10788)
                     /locus_tag="ROH59_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010260829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family plasmid-partitioning AAA ATPase"
                     /protein_id="HDX4806940.1"
                     /translation="MIIVLGSQKGGVGKSTLAVSIAAYLMSLGNRVIIVDADDQKSVL
                     TWYNNRPEDLPHIPVTGATGNIKAMLKEHEKSYDFVIADCAGRDSAEMRSGLMAADVF
                     ISPLRPSQMDLDVVPHTCSVFTAAKDFNEDVRGYLVLNMTPTNMFVNEANEAAEVLKD
                     YPEMHLANSRVCDRKAHRDAWAESMTIFETQNDKAQQEIEALVKEVIL"
     gene            complement(10992..>11192)
                     /locus_tag="ROH59_004544"
     CDS             complement(10992..>11192)
                     /locus_tag="ROH59_004544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
                     /protein_id="HDX4806941.1"
                     /translation="QPGLFDEIQPRKNSEKLMKTLDELNQSGKGTVWFAGRGTAPEWQ
                     MKREMLSPAYTTRWTDLPVAQL"
BASE COUNT         3032 a         2531 c         2587 g         3042 t
ORIGIN      
        1 attgataatt tttcgtacag acttgttttc cgtgggtatg taataactga aaaactcaaa
       61 tcataagatt ccagtctctt tataagttta tttattcttg ctggagtaaa gagatgtgaa
      121 tgcatgacaa tgatttcatc attattaatt gcttttgata tcagagaaag caatacatcc
      181 cagtgtttcc tcattgactt cgggcaacgt gtgtcagcat aggggctaag atgtatagtt
      241 gatttcttgc ttcccttttt cttcttcaca aagaatgtga agtcgtattt agatgcagac
      301 cttacaataa gaagtacaca tctgaaaagt agtgggaaaa tgcaaatcac aaccaccaca
      361 cagaaatata acatataagg caatgataag ttgtcagtgt atggataacg taagtattgc
      421 catggggtag tgatgtacag acaaagcgta caccaaagca accagagata taatggtgcg
      481 ttattatttt tcatgttggc tgaggcaggc gactaaaata acagactaag gaggattaac
      541 tgtttaattc tttggaacaa aaaaatgcag ttcctgatca tcacacacca ttgaataaac
      601 attttgcttc ggttgcgttc atgatagcca gtcctgtaga tgctgatggc gggagctgct
      661 gcccttgtgc cagcggcagt ggctgccggg agcacgctcc agtcggaaca gaaatcggtt
      721 gtcgcgtagt accaccacga gacagttatc cggcgtgcag aaacgtcggg caagctcatc
      781 ggggtctgtc ggtgttttcg ttgaaaacag cctgcgtttg cagtgtgcgt cgacgaccag
      841 tatttgcagt cgtccgggat gttgctgtgg catcaaagac tccttccgga acgggaaaag
      901 aagcagctgt accgtcataa ctgcacgtac cggttgcgaa aaaacggcac aagcgagtag
      961 tgacagaaag aatgtcggaa acggcaggaa gggcggtaca ggctgcgaag actggaaacg
     1021 gggtatgccg gggattacac atcctcagtg taatgtgata gtcgtctgct cctgtgttgc
     1081 accccagaca tcttctggca agctgggcag cccgataaat agggtgtgaa agagggtttc
     1141 tctgcgttcg atcccgaatt gatgttcgta tcctctcacc acctgaaatc cttcgtcgga
     1201 gaatattaac tctgccgttt ccagaagctg catagttttg cggtgtagtg gagtgatcag
     1261 ctgcaacgta actggtgccc tcatatcgcc tgtcggtaga aaacactctt cggtgcgact
     1321 tagttgtagc agatggcgtt tcccggaaca ggcccgttca atggattcat tgaacaccat
     1381 ctcaggccat gggcagacat aaatgcgcca gcctgctttc tgtaatttac ccagcgcagc
     1441 ccgaaaacga aacaacggac attccccgac agtggcagag ctgagaaaga gcgtattcag
     1501 cgttccgatg atgggaatat tgcgatcttt ttcggtcaat gcttttaacg ccatgatttc
     1561 gccagggaga ctactgaact caggatgtct gctggcacca gaaagccatt caagcaggta
     1621 atgccgtaat ccggtttcac tggttatatt gtggttttcc tgtgccgttt tcagggcatt
     1681 cagtgcacac cagagcaact ggcgcacggg atgttctgtc gtggtcatgc gaatgtccta
     1741 ctgtgagatg aaaagaagac cggtatccgt tctctccgcc acacgtgatg gcacgggccg
     1801 gcctttgata aaacgaatca atactctggg gtgaagcctt ttatttcttt cgccattaag
     1861 aaatacacgg ttccatcaaa agacaggggg agtccatggt ggggatggct tcgtgcaggc
     1921 ttcactccgg aatattctct tgaattgaaa aaagcccggc ccgaaggccg ggaaatactg
     1981 gctatgggat gtttacaagg cgctccataa agccgtgatg ttcggcattt gataccagtt
     2041 ccaggagcag ggatatcctc gactcaggct ggagagtatt ttccattctg aggagatact
     2101 gatattgtgc ttttgtcagc catatgctgg aagccgcatt cagctcttcc ctggctcccg
     2161 gatttagcac agggtccggg taaatcttca ttaatccatc aacaatatct ttattgacgg
     2221 gttttatttc accgccaaac ttcacgaaat caatgaaggc gctatggcga cgtaatgccg
     2281 atactggttg aatgtcaaaa ttagccagaa taaaaaagta ccctggaaaa atagcgaata
     2341 ttctttcacg gtgacagcac ctggagtctg cccgtcttat ctttcttgtt attaatggag
     2401 tccatggtac gacgttttgc tcattcagcc atgagaataa agattctctg tttttgccgg
     2461 ctgtattata ttgcgcaaga taccagttcc ggttattcag gtgttctata ttcacgaagt
     2521 tcaacgctcc gcgcaaaacc gatccatgat ggacgatttt gcgatgtcag gcgaatatgc
     2581 taaatcatat gtctgaagca gtgtccagcc catatctgga taaactgcag ttctgacagg
     2641 catataacca gcagactcta gtacgttctg tatcggtgat ttggcgaact cacagataaa
     2701 gaacggctaa gcactaatat cagcaataca gtggcacagt atcgtgatac gcgaaataaa
     2761 acatcagcac gtcagttcag agtaaggtcg ccatatatcg ggcatgagcc agatacaaat
     2821 aattgggaca ccgtctgaag tgatttgctt tattaaagta acttgtgctt ggtgtttatg
     2881 tttatcaatt tgggagcgcc tgtaaagtgc aaaatgcaat ttccatgaaa gtgtcccctt
     2941 taatggggac acctgttcac attttttcgt tttctttagc tgtattgcta atcatgaaaa
     3001 cgaacgttcg catcagcaca gcagagcgaa gtgcatcata tccttccaga tttaagttct
     3061 tcaggcttcg cttcaggtag gttcgtaccg tttcgggaga aagccgacag ttctgagcaa
     3121 tggcgtcgta aggaacaccc attgcgtaaa aaacgcagac tttaagctgg tttgttgata
     3181 gctcgggaaa catgccttcc aacagagtga tggccgggag tttctgtatc atttgaggtg
     3241 acatagcaaa ggtctccgat gacaacaaaa aacgctatca ccgagttcct acgctcattg
     3301 gtgatagccc agacgggggt aggaataccg gcgtcatcgg aaaccggcca ggctaatgcc
     3361 tgccccgcct gagctaccat agatgacgac aagaaataca agttcctgtc tttatggtat
     3421 ggcaaaaaac gacgccaaat gaagaaatta acttctgcgc cgacgatgac tacgcgggtt
     3481 cctacgcccg atcacagttt tgcctgtgac cagtaaaggg tacttagtat aacgtaccga
     3541 gtcaactaac cgcttaaaaa acatacaaaa aagcgtcaaa acttaacgct ccgcgccgaa
     3601 gcgatccagg catgatgctt ctgctttgtg gcgttcgaac atgctggtcc atatgcacga
     3661 aacggtgtct gaccctcgtc cagacaatcc gcagttctga cgaacatatg aacaaatatg
     3721 ctcttgtaga ggctgttgtt acacaattgg cgggctgtgt aacaaatggt tttattatct
     3781 aagaatcatt ctatttacga tcgaatgatc tacaaaatga ttttttaaag gttttttaga
     3841 tcgtttaatt gtcttaaaac agaatattat tctgttaggt tgatcggttg taagataaat
     3901 gatcgtgagt agaacaaaag tcgatctttt aatccaaaag aaggatctaa agcagaaaaa
     3961 tctgctttta aaaatagatt ttattttttt gacgcaggtc aagattaact cattagaggt
     4021 atcggtgagg aggcactgga agagaagaga tcgttgtaat gcttttcaaa ttaacgtaaa
     4081 gcgggtatat ttcggttgtt attagctgcg cagagggtgg cactctgtgg agcaaagcgg
     4141 cgaaagccgg acggcagaat gcgccataag gcattcagga gagatggcat ttacgggcag
     4201 taagtcagaa gaccgaagat gttccggaag ccataaaagg aaaaccccca caatctttcg
     4261 acgaacttgg cgggacggag aaagattatg ggggcctcac agaatacggg taaagtataa
     4321 tgaaaccgta ccagagattc aaccctgtgc agtgtataaa tacacggcac aatcgctccg
     4381 ccataagcga cagcttgtgg caggtctgaa gaatactcca tataacgcag tacactggag
     4441 tcagttagca cccgaagagc agatccgttt ctgggaagac tatgaagcgg gaagggcgac
     4501 cactttcctg gttgaaccgg aaaggaagcg cacgaagcgc cgtcgcggtg agcactccac
     4561 caaacccaaa tgcgaaaatc cgtcctggta tcgtcctgag ctctataagg cgctgagcgg
     4621 gcagctcggg cacgcctaca accgtctggt gaaaaaggac ccagtgaccg gcgagcagag
     4681 cctgcgcatg cacatgtctc tgcatccttt ttacgtgcag aaacgaacgt atgccggtcg
     4741 caaatatgct ttccgtccgg aaaaacaacg cctcctcgat gccatctggc cggttctggt
     4801 cagcttcagt gatgcgggca cacataccgt aggcatgagt gtttcccgtc tggccagaga
     4861 aatcagcccg aaagacagca aggggaaggt tattccggaa ctggaagtga cggtctcccg
     4921 cctttcccgt ttgctggccg aacaggtacg ttttggtgtg ctgggtgttt cagaggaaac
     4981 cctgtgggac cgtgaaaccc gccagcgtct gccacgttac gtctggataa caccggcagg
     5041 ctggcagatg ctgggcgtcg acatggtgaa acttcacgaa cagcagcaga agcggttgcg
     5101 tgaaagtgaa atccgccagc aactcatccg ggaaggcgta ctgcgtgagg atgaagatat
     5161 ctccgtacat gcggccagaa aacgctggta tctgcagcgc agccaggatg cactgaaaca
     5221 ccgtcgtgca aaagcggcag ccagtaagcg cgccagacgt ctgaagaaac tgcctgccga
     5281 ccagcagatt catgagatgg cagagtatct caggaagcgt ctgccgccgg atgaagccta
     5341 tttttgttcc gatgaccatc tgaagcgact ggccatcagg gagttgcgtc agcttgaact
     5401 gacgctggct gcgccaccgc cgcactagac agcaccattc cttcagcact gaatcatcgc
     5461 cagcccctcc ggggctttcg gcgctggttc cgctcagccc aaaatctgca gtaatcacct
     5521 taaatcccct cagaggggca tatctgtcca taaaaccacg tatcagtcat cagaacatgg
     5581 ccacgttgtt tcagttatcc acataaatcc gcaaacaaag aactttaaaa agctgcaaac
     5641 ctgaaacagc aaacctgcaa tatagtccta cccccattat ttaatcccct gcgttgcttc
     5701 gccgcaggga aagtctttat ctctgaaacc actgtgaaca aatacagaga ggccttcgct
     5761 tgcagcggcc aaggccgcgc cgctcagaat ctaaaagcac ctcccacgct gacgcgcggg
     5821 ccccgaacct caccgttctg aaaccacaac aaaaagacat caggaataaa aacaccgcac
     5881 aaacgcagca ccgtgcctac ccctcataac tgaaaagcga ggccgccccc gcccaaaggg
     5941 cgggaacaac atcgctttta attatgaatg ttgtaactac attatcatcg ctgccagtct
     6001 tctggctgga agtcctccgt acacgctcgt aagcggccct gacggcccgc taacgcggag
     6061 atacgccccg acttcgggta aaccctcgtc gggaccactc cgaccgcgca cagaagctct
     6121 ctcatggctg aaaacgggta tggtctggca gggctgggga tgggtaaggt gaaatctatc
     6181 agtccgtacc ggcttacgcc gggcttcggc ggttttactc ctgtgtcata tgcaacaaca
     6241 gagtgccgcc ttccatgccg ctgacgcggc atatcctggt gacgatatct gaatcgttat
     6301 atactgtgta taatatatgg tgcgttaatt tttaaaccct tatttaattt cctcgtcagt
     6361 tagatattgt ccgtttccca aacgaagccc ttcagagacg tcgtgtaaac acggtccttt
     6421 tatcttacag gttaacccct atcaatctta ggatgaaacc acgccatcct ctgcttgcct
     6481 ggttattaat ttcatatcat cttatgcctt ttttatcttc atttgggacc gtacttttct
     6541 tcggaatatc actattcgtt aactgctgtt catcaataaa attcctgatg atattcagtt
     6601 cactctgacg gattttttct tcttcatttt ttctcagaag acggcagata tccatttcat
     6661 cccgcccggt cattcttttt ccggaaaaaa ggcggttaag cagctcctgc tttacatctg
     6721 gtgagtcttt ggtggcctcc atgaggttga gcagactctg acgatcgaga atagagaaaa
     6781 cttttgggaa ataatgtaaa aggaaaagaa cccagaatgc tgtccatgca aagcagagaa
     6841 aagctgctgt aagcacgtga ttcttgcctg ataggtatat aatcagcaga acaaccgaaa
     6901 tccaagatgc cagttctaaa aaagtatata caggcttcag gcgtctgtat gcctgttcat
     6961 gattattcag gatgaattga attttttctg cacctgattt actcataata attctcttcc
     7021 catttttctg atacgtaatg tccagctgtt atcaggagtg tttattgccc agaaatattc
     7081 tcctgctgtg cctgcatcct gagcaacttt tgttctaatg tcaccagtct gcgaccggca
     7141 ctctgtgctt cagattctga gacctgccct ttggggtgac catccagacc ataacgtggg
     7201 acgccggcga cagctgtccg ctgcagatat acacggcgtg aggtgatgca ggacactgca
     7261 cagagccatt cgtccatggt cagttctgtc tccgggtgtt ctgccagaaa tgctgaaata
     7321 tcattgttta tgccaatttt caggggaata aatccaccac cttcagcacg aagatgagga
     7381 aacaggatct ttattttttc cacgcactcg tgagtatact ctctggtcca gtgggaggga
     7441 cgtgggaaac ggcgtttttt ctttttcttc ttcctggctg gtgcttcggg gatatgtgtt
     7501 tcgacggcag atgaatttat tccgacgggg gctgattctg ctgcctgttc agtaaatgca
     7561 gattcgataa tatctgtttt ttcggataag gaaggtaacg aaaaggtacg acgttttttc
     7621 actacaatga cggggatttt cctttcttcc tgattttttt ccataaatac ctcggctggc
     7681 tggttttact ctttaataat atcacaatcc ataaattagt aaattttccg tcaggtgatt
     7741 tttcatggtt tataagtccg ttctctgaat atttatactc gaggcggtaa cagttatggc
     7801 gtgacagtcg aattgatatt cgactgaacc ctgaccgaaa catggttgat atattctcta
     7861 acgttaatgt tgtcatgata taaataaaaa aaattcattt gaaaggatgt cagaagaaga
     7921 tatcggggcg cacagttcat ctctgccttt gtttcatggt gtgttctttg tatattttac
     7981 ttactgttta agcatgtaca taaggagtgc tttcattatg ccaatgatac ttgtaaagaa
     8041 gaatccccgg ggcaaagtga ttcgggagct tagcagtgag gaagagactg cagtaaagac
     8101 ggtctgtgga ctgaaaaagc cagcaaccat ggcacaacat aacctggcca atgatcttct
     8161 ccgggaaatg cgtgagtatg atgcatggtt acagtgtgac tgtattccgg gagattcgcc
     8221 ggccatgaat tttgctgctc ttaaaaacaa tacgggtact ctttatctgt ccagttttaa
     8281 tcatgagcat gcacctgaat gccccatgta tcgtcagtta tcaggaaatg aagaggaaac
     8341 atccttcgga gcaagccggc atcccgttag cacccgtata aattacagaa actttttacc
     8401 acctgatgac agtaattctg ttatcagact gcagacccgc tctgcttacc ataatggtga
     8461 gcgctcctcc gttcgcaaga aacgtccgcg ccttggccgt ttactcctgt cgcttattga
     8521 agatgcaggg ctgaataaac tggattccct ggctaatccc cgtatccgga ctaattatcg
     8581 tgagtgtctt gatgccatac ggcaggttac actacagcag gagtatattc ggggaagatc
     8641 cttatctgaa attatccatt tccggccagg aatgtctgaa aggtctcagg agcggttaat
     8701 ggaaacgctg gagaattcag aacgacactg gcctgccaga agaaaacata tgttctttca
     8761 gatttttatg gcgcagcaca tctgtcgtga tgctgtggaa attcactggg cgaacggtaa
     8821 tattcaggtc ttcagacctg tgcgggggat cagtattaat ggtgaagcgc agggcggaat
     8881 acgtccccct tactgggtta ttcttgcttt ttgccggagt gccgatggca gaatcatctg
     8941 cagtgaaggg tatgctcatg ctctttatca actgacatgt ccggttcctg tggacagcaa
     9001 actggaacga aacacgctca ctgctcttct gaatgtggcc agctggctta aaagaaagcc
     9061 aggtacgccg gaattaagtc tggaaaggcc cctgtttgat acagaagttt atgttaatgg
     9121 tgaaaagaaa tatgtactgc cggatttcat tgtcacagca agggctcctg acggaaagac
     9181 ggccagagtg gtcatcgaaa cgatgggata tgaagacagt gattactgcg cgagaaaatc
     9241 caggcagcat accggcatga agcagattgg tgttctgcat accgatccac cgaaatggct
     9301 ggataacgat catccccctt ttgagaaaca tatgtacggt gtttttatgc atctcaggta
     9361 ctgagatatt ttgtggctca gttctgtaac ttttcccgta acattgtctg ttgttacggg
     9421 aaagtccggt ttttgtattg caccagagaa tactcagact gtgatgctgc cacagcgtca
     9481 gcaggctttc tgaacggtgt aacatcactt catgttaatg ataatcacta tcattaaatc
     9541 ttgacatgcc attttctcct taataaatta atactgtata tgtatccata tacgtaagca
     9601 gttaattcat ttgttttcct cagaggatga aggagatacc gaatgtctga tcctgtacgg
     9661 ggttcagtga gttagctggc ctggatgtaa ccactcgttc aactcaattc tcttagcgtg
     9721 ggaaaatttc cgcttttcca agcggacccc tattaatatt tgttttgttt taggttctat
     9781 tcaacatagg tcatcctaaa atacattgaa gataacaaga taacaagata acaagataac
     9841 aagataacaa gatagtaagg tgttatcttt gttttacttc tgctatcaat cgtgatacct
     9901 ctgtttttga tagtgtttta agtgcttcta ccgccgccct gacaacatca gaacgattca
     9961 ctctgccttt acctgaaacc atctcagccg ttataagggc atcaatgtct tttaggtttt
    10021 cttcaaaaaa agaaatactc actggttttg ctttgcttac aaccgatgat ttatctgatg
    10081 actttttggt attatcaagg ccagccgtgc caccgttaat aaatgctgcc tcgtcacgag
    10141 gtgaagtgtt tgctctattt ctcacagaat aacctctttc actaacgctt cgatttcttg
    10201 ctgggcttta tcattttgcg tttcaaaaat tgtcattgat tcggcccaag catctcgatg
    10261 tgctttacga tcacataccc gggagtttgc cagatgcatt tcagggtaat ccttaagtac
    10321 ttcagctgcc tcattggctt cattaacaaa catatttgtg ggcgtcatgt ttaaaacgag
    10381 atatccccga acatcctcat taaaatcttt tgctgctgta aaaacggagc atgtatgagg
    10441 cacaacatcc aggtccatct gagatgggcg caaaggagaa atgaatacat ctgcggccat
    10501 caatccacta cgcatttctg cgctatcacg gccagcacag tctgcaataa caaaatcata
    10561 ggatttttcg tgttccttta acatggcttt gatgttacct gtcgcgcctg taaccggaat
    10621 atgagggaga tcttcagggc gattgttgta ccaggttaat actgatttct ggtcatctgc
    10681 gtcgacaata atcactctat tgcctagtga catcagatac gcagctatag ataccgccag
    10741 tgtactttta cctaccccac ccttttgact acctaatact attatcatta tagcctcata
    10801 ttaagctgtt aagttaacaa cttaatattg ccatctgaac gcgaaccatg caattatttt
    10861 tgttatgtta acaacttaac aagctgttaa gtatttgatt tatagattaa ttaagataac
    10921 aagataacaa gataacaaga taacaagata acaagataac aagataacaa tattatgggt
    10981 ggattacata ttcataactg ggctactggc aaatctgtcc atctggtggt atacgcagga
    11041 gaaagcattt cccgtttcat ttgccactca ggggcggttc ctcgccccgc aaaccacact
    11101 gtcccttttc ccgactggtt cagttcatcg agtgttttca ttaacttttc actgttttta
    11161 cggggctgga tttcatcaaa taatcccggc tg
//
LOCUS       DAPOXO010000127        11125 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPOXO010000127 DAPOXO010000000
VERSION     DAPOXO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11125
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.127"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1339)
                     /locus_tag="ROH59_004545"
     CDS             complement(<1..1339)
                     /locus_tag="ROH59_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HDX4806942.1"
                     /translation="MTSKNFALITAMTQAELTQKVNEHLAKGWHLQGETRVAYEPGTP
                     WYLMQAMVADGTTDISPDSPQHGSVPEWYYVVVLAGQSNAMSYGEGMPLPDSYDAPHP
                     RIKQLARRNTVTPGGKACAFNDIIPADHCLHDVQDMSALNHPNADLSKGQYGCVGQGL
                     HIAKRLLPYIPQNAGILLVPCCRGGSAFTQGAEGTFSESTGASQDSARWGVGKPLYQD
                     LILRTKAALQKNPKNMLLAVCWMQGEFDMSAATYSQQPPLFTAMLKQFRADITEFNTQ
                     CHGGRAASVPWICGDTTYYWKNTYGTQYDTIYGAYKNRESDNVFFVPFLTDGSGNNTS
                     TNAPTEDPDAASEGYYGSASRTNKNWVSSNRQTHFSSWARRGIIPDRMATAILNVAGR
                     TLAFISGKAPEIKPSPGGDTPSGPSEDASVRTISLLPTAGDAAAQGWSIKNGGI"
     gene            complement(1478..1873)
                     /locus_tag="ROH59_004546"
     CDS             complement(1478..1873)
                     /locus_tag="ROH59_004546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2570 domain-containing protein"
                     /protein_id="HDX4806943.1"
                     /translation="MKLWPTLGVAFLLITSMRLSWSLGRENARNEAQASTLKSTVDTL
                     NIISAGVQDMQQVLAQLRAENQQRNQDGEVRREQLRNDIAKDECAHALPDARFTDRLR
                     RHAERARASAVSPAYTADADHAGNASPLP"
     gene            complement(1870..2262)
                     /locus_tag="ROH59_004547"
     CDS             complement(1870..2262)
                     /locus_tag="ROH59_004547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDX4806944.1"
                     /translation="MSNTFKFSSRSEKNLQGVNPDLVKVTRRALEISEVDFGITEGLR
                     SRYRQKQLVTTGKSQTMNSRHLTGHAVDVVAYVGNQVSWEWPLYEKIAAAFRQASQEL
                     NIPVEWGGDWKTLKDGPHFQLPHGAYPA"
     gene            complement(2259..2582)
                     /locus_tag="ROH59_004548"
     CDS             complement(2259..2582)
                     /locus_tag="ROH59_004548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDX4806945.1"
                     /translation="MSTIQTGITEQVIAWLFDHLPTVYAVGAAVSISALMSLYDGRTL
                     VQTVTGSLACGVLAMAVAGSLRFFGIPEDAVTFFGASIGFMGAEKARDKVIAIFDRRV
                     KERNE"
     gene            complement(2585..2785)
                     /locus_tag="ROH59_004549"
     CDS             complement(2585..2785)
                     /locus_tag="ROH59_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HDX4806946.1"
                     /translation="MKVKALEGDTVDSLCFRYYGTTQGVTEKVLDANPGLCQQVFLDA
                     GQEVEMPEPEKKKREMIQLWGE"
     gene            complement(2785..3279)
                     /locus_tag="ROH59_004550"
     CDS             complement(2785..3279)
                     /locus_tag="ROH59_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HDX4806947.1"
                     /translation="MSMVARTNPGPAEDDITDTDDGDTRISAGAFWPDIVLRELRLAV
                     RLPGRVTTSRLLHTATGAIAHVTRELEAWQQEQQAAGYQTLADVPAPVINGESVNLWH
                     WRNAVYTATRALILERYRDADTTDKGDRRADALDIQTSDLWRDVSWAISDILGRPRMF
                     AELC"
     gene            complement(3381..4181)
                     /locus_tag="ROH59_004551"
     CDS             complement(3381..4181)
                     /locus_tag="ROH59_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDX4806948.1"
                     /translation="MITPAQQHWQNVMAQRAGRANEGVDHAACTAHEEVLYRLRLAQA
                     RLKAIQARSAKAAIKKELLPDFSGWIEGTLEADGGQQDEVIATLMVWAIDCGDLPLAL
                     RIGAYVVRHNLIMPDNFGRTAATVLTEEICNPVLTQAGTDADADLSAFIEPLDTLWEI
                     IANQDMPDEVRAKLCKACAFARRGLTDADNMASSLKLLREAMHLNPNAGVKREIATLS
                     RALKKADSAAEPEDASAQQAQDESSKSKKTTRKPATRKTTATQKAKRG"
     gene            complement(4227..5279)
                     /locus_tag="ROH59_004552"
     CDS             complement(4227..5279)
                     /locus_tag="ROH59_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HDX4806949.1"
                     /translation="MNLVMSDITRNKLGCYMAQQASLNNIPVSALVSRFTVEPAVQQR
                     FENASKESTEFTKRINVIGVTDQKGEKILLDTTGPIARTNSSYDGIKRRNPNNVIDMK
                     SRQYQCEQVNYDTFISYPQLDTWAAHSDFQSRISTQIARQVALDRIMIGFNGTSHAYE
                     SDFHTNKLLQDVNVGWLEHIRTDASERVMNDVTLTSRNMDNTVAHAGKYANADALVQD
                     ARSSLLDEWHKEADDLAVIMGRNLFNSLRLPVLNSISGQNPNAELLAGQLILSSRTIG
                     GLGVFLAPFFPDATMLITSFNNLSIYWQKGSMRRLMKDEPEYNRIATYQSINDAYVVE
                     DYGKCAMVTGLKFADS"
     gene            complement(5303..6139)
                     /locus_tag="ROH59_004553"
     CDS             complement(5303..6139)
                     /locus_tag="ROH59_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HDX4806950.1"
                     /translation="MANEKKTSRKKFRVAVSGSTVDGREISPVHLREAAENFNPDVYA
                     ARVNVEHYLSPCPSSEFSAMGDVTALSTEDITEGPLAGRTALYAEIEPTERMKQLVAD
                     GKKIYSSIELHPQFSVNGRAYLVGLAMTDTPASLGTERLKFTAQQRQAVMTFNSIQGE
                     APLISEAIESEIIEMAEQRQEEGTQWFNRVMGIIGRGRKADDASFSRIQEAVEGVATS
                     QADIIDRFNVLETRHQQDRQKITSLTTELTALKEKLRTQDGDPQNRFTATGAASDQLA
                     DF"
     gene            6294..8045
                     /locus_tag="ROH59_004554"
     CDS             6294..8045
                     /locus_tag="ROH59_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase family protein"
                     /protein_id="HDX4806951.1"
                     /translation="MIQDAFVRQRARQLYWQGYPPAEISRLMGINPNTIYAWKKRDQW
                     DETPPVQRVTQSIDARLIQLTEKQNKTGGDFKEIDLLTRQLKKLHDGQPDVMAAGKKG
                     RAKKLKNHFTPEQIAALREKIISRLEWHQRGWFDSLTLCREAGIRNRMILKSRQIGAT
                     WYFAQEALLMALRDDVAQPYQRNQIFLSASRRQAFQFKSIIQKAAAEVDVELKGGDKI
                     ILSNGAELHFLGTSAASAQSYTGNFYFDEFFWVSRFAELRKVAGAMATLSGLRRTYFS
                     TPSTETHEAYAYWNGDRWNEKKASHKRQRFSVDWKTLHNGLICPDRTWRQIVTLEDVV
                     NHGWKHTDIDEIRDENTEDEFLNLYMCEFVREGESAFNLNILIGCGVDGYDDWKDWKP
                     FAPRPMGNRPVWIGYDANGSSGNGDSGAVSVVVPPAVPGGRFRTVETRRVQGLEFEEQ
                     ARVIEEFTCRYNVEHIGIDVTGGNGEAVYQIVKRFFPAAIPYTFTLSSKRSLVLKMLQ
                     IMRAGRWEYDRAERELVAAFNAVRKVKTPGGFITYETDRARGISHGDLAWATMLAVIN
                     EPIGGEGENERFMVMEF"
     gene            8045..9091
                     /locus_tag="ROH59_004555"
     CDS             8045..9091
                     /locus_tag="ROH59_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDX4806952.1"
                     /translation="MSRKNKKVRMSSRIDLADALRKESSLSAFTFDGPYRLTGHDLLD
                     NMYCADNGRWYETPVDWYGLARAARQTSWHQSALYFKRNVLLGCYIPHPLLSRQDFSA
                     LALDWFVFGNAFLELRSNMLGEPLKLRHALAKYMRRGSDLESWWYVQDGKDAFQFRPG
                     KVCHLMNPDINQEIYGMPEYLGALLSASLSHSADMFRKLYYDNGSHAGCIIYIGAAQV
                     NRESMDSLKETLQGARGGGAFKNVLIHAPNGGKEGVQILPFQQITAKDEFMNVKAASR
                     DDVLAAHRVPPQLMGAMPGEKSAFGDVEKAARVYAINELMPVMEAMKHINDWLGEEVI
                     RFNSYALLDEKTAP"
     gene            complement(9106..9630)
                     /locus_tag="ROH59_004556"
     CDS             complement(9106..9630)
                     /locus_tag="ROH59_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806953.1"
                     /translation="MVINYKQLREKREQVKESFRRNEDLTPLVRLAQGIVDAYEISLE
                     LPSQTWTDSDGNRQHYVSCGLEAAEGFRRMPLSQIPAATPKARGSNDERKLTFSIETV
                     VDDTPGEVAFVHTPVSIAMYNDEIQVRVNNNIVPLKEGNSPYTTVCEAIQYYVLSEID
                     NLKPDGTQKMVQLW"
     gene            10354..10851
                     /locus_tag="ROH59_004557"
     CDS             10354..10851
                     /locus_tag="ROH59_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4760 domain-containing protein"
                     /protein_id="HDX4806954.1"
                     /translation="MNPITLQIISNAIVLLGVLVAIGTIIYNVRTAKKTQTANFLFES
                     RQDMQYIESLHTLKQVHRSGKSFRSYVFPCDGCIITDEEMAERRKFQYILNFYERVAV
                     SIREGIYDEKMIKRTSYTTVVETYDIAEPLIKAIRESINSDTTYQEFEWLVRRWKANP
                     LRKNK"
BASE COUNT         2455 a         2896 c         2967 g         2807 t
ORIGIN      
        1 gaattccgcc attcttaatg ctccagccct gcgcagcagc atctccggct gtcggcaaca
       61 gggagattgt gcgtacggat gcatcttcag acggccccga tggcgtgtcg ccgccgggcg
      121 agggtttgat ttccggtgcc ttaccactga tgaaggctaa ggtgcgaccg gctacgttca
      181 gaatagcggt tgccatacga tcgggaataa tgccacgacg cgcccatgag ctgaaatgcg
      241 tctggcgatt tgatgatacc cagtttttgt tcgttcggga tgccgaaccg taatatccct
      301 cacttgcagc atccggatct tccgttggtg cgttggtgga ggtattgttg ccactaccat
      361 cggtcaggaa cggcacaaag aaaacgttgt cgctctccct gtttttgtac gccccgtaaa
      421 tggtgtcgta ctgcgtgccg taggtgtttt tccagtaata cgtcgtgtca ccacaaatcc
      481 atggcacact tgccgctctg cctccatgac actgcgtgtt aaactcggta atgtccgcac
      541 gaaactgttt cagcatggcc gtaaacagcg gaggttgctg tgagtacgta gcggcgctca
      601 tgtcaaattc gccctgcatc cagcatacgg ccagcagcat gttttttggg tttttctgca
      661 atgcggcctt cgtgcgcaaa atcaggtcct gatataaagg tttacccaca ccccagcgag
      721 ccgaatcctg actggctcct gtggactcgc tgaatgtccc ctccgcgccc tgggtgaatg
      781 ccgaaccacc acgacagcat ggaaccagta aaatcccggc attctgtgga atgtaaggca
      841 acaggcgttt ggcaatatgc aagccctgtc cgacacagcc atactgccct ttgctcaggt
      901 ctgcattcgg gtgattcagt gcgctcatat cctgaacatc atgcaggcag tggtctgccg
      961 gaatgatgtc gttaaatgcg catgctttac caccgggagt cactgtgttg cgacgggcca
     1021 gttgcttaat gcgtgggtgg ggcgcatcgt aagaatccgg cagcggcatt ccctcaccat
     1081 atgacatggc attggattga ccagcaagta ccaccacgta ataccactcc ggcacgctgc
     1141 cgtgctgggg ggaatcaggt gagatgtctg tagtgccatc ggccaccatt gcctgcatta
     1201 gataccacgg ggtgccgggt tcgtaggcaa cccgcgtctc cccctgaaga tgccaccctt
     1261 tcgcaagatg ttcattcacc ttttgagtca gttcagcctg tgtcatggct gtaatcagtg
     1321 caaagttctt actggtcatt gtgttactcc cgtctggtgt gtcagttcgg ctattctctt
     1381 atccagttca gcaatggccc gtttatccgc gttacaggtt tccagtgcat ccagaaggcg
     1441 gtcgccccat attccgaggt ttccccatgt gggtgggtca gggaaggggg gaggcgttac
     1501 cggcatggtc agcgtctgcg gtataagccg gactgacggc gctggccctg gcgcgttctg
     1561 cgtgcctgcg caacctgtca gtaaaacgag cgtcaggcaa agcgtgggcg cattcatctt
     1621 ttgcaatatc gttgcgtagc tgttcacgtc ttacctctcc gtcctgattg cgttgctgat
     1681 tttccgcgcg gagctgagcc agcacctgct gcatatcctg taccccggcg ctgatgatat
     1741 tcagtgtgtc gacggtactt ttcagggtgc tggcctgcgc ttcgtttctg gcgttctccc
     1801 ggcccagcga ccacgacaga cgcatggatg taatcagaag gaaagcgacg ccaagcgtgg
     1861 gccagagctt catgccggat aggctccgtg tggtaactga aaatgcggtc cgtctttcag
     1921 ggtcttccag tcgccgcccc attccaccgg aatattcagt tcctggctgg cctgtctgaa
     1981 tgctgctgcg attttttcgt acagcggcca ttcccatgac acctggttgc cgacataagc
     2041 cacaacatcc acggcatgcc ctgtgagatg gcgactgttc atggtctggc tcttgcctgt
     2101 ggtcacgagc tgcttctgac gataacgact gcgcaatcct tcggtgatac caaaatccac
     2161 ttccgagatt tccagcgccc gtcgggtcac tttcaccaga tcaggattta caccctgcaa
     2221 attcttttcg ctccggctgc tgaatttaaa tgtgttgctc attcgttcct ctccttcacc
     2281 ctgcgatcaa atattgcaat aaccttgtcg cgtgctttct ctgcgcccat aaaaccgatt
     2341 gaggcaccaa aaaacgtcac tgcatcctca gggatcccga agaagcgcag cgacccggcc
     2401 acggccatgg caagaacgcc gcacgccagc gatcccgtta cggtctgaac cagtgttcgt
     2461 ccgtcataaa gactcatcag cgcggaaatg ctgaccgccg cgcctactgc atacaccgtt
     2521 ggcaggtggt caaagagcca cgcaataacc tgctctgtga tccctgtttg aatggtgctc
     2581 actgctactc cccccacaac tgaatcattt ctcgtttctt cttctccggc tccggcatct
     2641 ccacttcctg cccggcgtcc agaaatacct gctgacagag tccggggttg gcatccagca
     2701 ccttttcggt gacgccctgt gtcgtgccgt agtaccggaa acagagcgaa tccacggtgt
     2761 cgccttccag tgccttcact ttcatcagca cagctccgca aacattcgcg gtcgtcccag
     2821 aatgtcagag atggcccagc tcacatcgcg ccacaaatcc gatgtctgta tatccagtgc
     2881 gtccgcccgg cggtcgccct tgtccgttgt gtccgcatcg cggtaacgct ccagaatcag
     2941 ggcgcgtgtg gcggtataaa cagcattgcg ccagtgccag agattgacgc tttctccgtt
     3001 aattacaggg gccggaacat cggccagcgt ctgatagcca gccgcctgtt gttcctgctg
     3061 ccatgcttcc agctcgcggg taacgtgtgc tatggccccg gtggcggtat gcagcaggcg
     3121 ggaggtggtc acgcggcccg gcagtcgtac cgccagacgc agctcgcgca gcacaatatc
     3181 cggccagaat gcacccgctg aaatacgggt atcgccatca tcggtgtcgg tgatgtcgtc
     3241 ctctgcgggg ccggggttag ttctggcaac catactcatg gggttcactc ctgaaaaaat
     3301 cgggcggtgg gtgcgcggtg taaacggtca cggagtcaaa ccggaacacc gcgcacgccg
     3361 cccgctgacg gggtcagtcg ttaaccgcgc tttgccttct gcgtcgcggt ggtttttcgt
     3421 gttgcaggct tccgcgttgt ctttttactt ttgctgcttt cgtcctgcgc ctgctgtgcg
     3481 ctggcgtctt ctggttcggc tgcggaatcg gcttttttca gggcgcggga aagggttgca
     3541 atctcgcgtt tcacacctgc gttcgggttc aggtgcatcg cttcgcgcag cagcttcagt
     3601 gatgaggcca tgttgtctgc atcggtcagg ccacgacggg caaaggcaca cgccttgcat
     3661 aatttggcgc gcacttcgtc cggcatgtcc tggttggcga taatttccca aagtgtgtcc
     3721 agtggttcga taaaggcgga taaatccgcg tcggcatccg tcccagcctg cgtcagtacc
     3781 gggttgcaga tttcttcggt cagtaccgtg gcagcagtac ggccaaagtt atccggcatg
     3841 atgaggttgt gacggaccac atatgcacca atacgcagcg ccagcggaag atcgccgcag
     3901 tcaatcgccc acaccatcag cgtggcaatt acttcgtcct gttgcccgcc gtcagcctcc
     3961 agcgttccct caatccagcc ggaaaagtcc ggcaacaact cttttttgat ggcggctttc
     4021 gcgcttctgg cctgtatggc ctttagcctg gcctgtgcca gacgcagacg atacagcacc
     4081 tcttcatgcg cggtacacgc ggcgtggtcc acaccttcat tcgcccggcc tgcgcgctgt
     4141 gccatcacgt tctgccagtg ttgttgtgca ggagtaatca ttttttctct ccgttacagg
     4201 cgggcatgat gcccgccgtg agttgattag ctgtcggcga acttcaggcc agtgaccatc
     4261 gcgcacttgc catagtcttc aacgacataa gcgtcattga tggactggta ggtggcgatg
     4321 cggttgtatt ccggctcgtc tttcatcagg cgacgcattg aacctttctg ccagtaaatc
     4381 gacaggttgt tgaacgaggt gataagcatc gttgcatccg ggaagaacgg cgcaaggaac
     4441 acgcccagcc cgccaatggt gcgcgatgac aggatgagct gcccggcaag taattccgca
     4501 ttgggattct ggccgctgat gctgttcagc acgggcagac gcagcgagtt aaacaggttg
     4561 cgccccataa tcaccgcgag gtcgtcagct tccttgtgcc attcatccag cagggatgag
     4621 cgcgcatcct gtaccagagc atcggcattc gcatacttac ccgcgtgcgc cacagtgttg
     4681 tccatgttgc gggaggtcag cgtcacgtca ttcattacgc gctcgctggc atcggttctg
     4741 atgtgctcca gccagcccac gttaacgtcc tgaagcagct tgttggtgtg aaaatcagac
     4801 tcgtaggcgt gggatgtgcc gttaaagcca atcatgatgc gatcaagcgc tacctgccgg
     4861 gcgatctgtg tactgatacg ggactgaaaa tcgctgtggg ccgcccaggt atcaagctgt
     4921 gggtacgaaa taaaggtatc gtagttcacc tgttcgcact ggtactgacg agacttcata
     4981 tcgatcacgt tattcgggtt acggcgtttg atgccgtcat aactgctatt cgtgcgcgca
     5041 attggcccgg tggtgtccag gaggattttt tcgcctttct ggtcggtcac gccgatcacg
     5101 ttaattcttt tcgtaaattc ggtactttcc tttgaggcgt tttcaaaacg ctgctgcacc
     5161 gcgggttcca cggtaaatcg cgataccagt gcagataccg ggatattgtt aagcgacgcc
     5221 tgctgcgcca tatagcaacc cagcttgttg cgggtaatat ctgacatcac cagattcata
     5281 aaaaatttgc tcctttgtct tatcagaagt cagccagctg gtcggaggct gcgcccgttg
     5341 cggtgaagcg gttctgcgga tcgccgtcct gcgtgcgcag tttttccttc aatgctgtca
     5401 gctctgtggt cagtgacgtg attttctggc ggtcctgctg atggcgggtt tccagcacat
     5461 taaaacggtc gataatgtcg gcctgtgacg ttgcaacgcc ttccaccgct tcctgaattc
     5521 gggagaaact ggcgtcatcc gctttgcggc cacgaccaat aatccccatt acgcggttaa
     5581 accactgggt gccttcttcc tggcgttgtt ctgccatttc gatgatttca gactcgatgg
     5641 cttcggagat aagcggtgct tcaccctgga tactgttgaa cgtcatcacc gcctgacgtt
     5701 gctgtgccgt gaatttcagg cgctcagtgc ccaggcttgc cggggtgtcg gtcatcgcca
     5761 gcccgaccag ataggcgcgc ccgttaacgg agaactgcgg gtgcagttcg atactggaat
     5821 agattttctt gccgtcagcg acaagctgct tcatgcgctc ggtcggttcg atttctgcat
     5881 acagcgcagt acgtccggcc agcggacctt ccgtaatgtc ttccgtactc agtgcggtga
     5941 catcgcccat tgcggaaaat tcgcttgacg gacatggcga gagatagtgc tcaacgttca
     6001 cgcgggcagc gtaaacatcc gggttgaagt tctcggcggc ttcacgcaga tgcaccggac
     6061 tgatttcacg gccatcaaca gttgatccgg agacagccac gcgaaacttt ttgcgggatg
     6121 tctttttttc attagccata gtttttgccc ctctgactgg ttcttcagtc atgatggcaa
     6181 agcgtaacag gctgatacaa agggcttttg ttgtaagaaa acagtcagaa cagagggtta
     6241 aggagaacag tttcgcgcgc gggtaatctt cctgtaatta ctcaggggga gcaatgattc
     6301 aggacgcttt tgtgcgccag cgtgcgcggc aactttactg gcagggttat ccgcccgcag
     6361 aaatatcacg tctgatggga ataaacccga acacgattta tgcgtggaaa aaacgtgacc
     6421 agtgggatga aacgccaccc gtgcagcgtg tcacgcagtc catcgatgcg cgcctcatcc
     6481 agcttactga aaaacagaat aaaacaggcg gtgactttaa ggaaatagac ctgctgaccc
     6541 ggcagcttaa aaagctgcat gatggccagc cggatgtgat ggccgcagga aagaaaggcc
     6601 gggcgaaaaa actcaaaaat catttcacgc cggaacagat tgccgcactg cgggaaaaaa
     6661 tcatcagcag gctggagtgg catcagcggg gctggtttga ctccctgacc ctttgcaggg
     6721 aagccgggat acgtaacagg atgatcctga aatcccgaca gattggggcg acctggtatt
     6781 ttgcacagga agcactgctg atggcgctgc gtgacgatgt ggcgcaacct taccagcgta
     6841 accagatttt tttgtctgcg tcgcgtcgtc aggcgttcca gtttaaaagc attattcaga
     6901 aggccgcggc tgaagttgat gtggagctga aagggggcga taaaatcatc ctctccaacg
     6961 gcgcagagct gcattttctc ggcacttctg ctgcgtcggc acagtcctat acgggcaatt
     7021 tttattttga tgaatttttc tgggtcagtc gctttgctga actgcgcaag gtggctggcg
     7081 ctatggcaac cctcagcgga ctgcggcgca cctacttctc cacgccatcc accgaaacgc
     7141 acgaggcata cgcctactgg aacggcgacc gctggaacga gaaaaaggcc tcgcataaac
     7201 gccagcgttt ttctgtggac tggaaaacgc tgcataatgg gcttatctgc cctgaccgga
     7261 cgtggcggca aattgtcacg ctggaagatg tggttaatca cggctggaaa cacaccgata
     7321 tcgacgaaat tcgtgatgaa aacaccgaag acgagttcct caatctctat atgtgtgagt
     7381 ttgtccgcga aggggaatcg gcatttaacc tgaatatcct gattggctgc ggtgttgacg
     7441 gatacgacga ctggaaagac tggaaacctt ttgctccccg cccgatgggg aatcgtccgg
     7501 tatggattgg gtatgacgca aacggcagta gtggcaacgg cgacagcggc gctgtgtccg
     7561 tggtggttcc tccggctgtt cctggcggcc gttttcgaac ggtggagacg cgacgcgttc
     7621 aggggctgga gtttgaagaa caggccagag tcattgaaga gttcacgtgt cgctacaacg
     7681 tggaacacat cggcattgat gtgacgggcg ggaacgggga ggctgtttat cagatagtga
     7741 agcggttttt ccctgctgct attccgtaca ccttcacgct gtcatcaaaa cggtcgctgg
     7801 tactgaaaat gctgcaaata atgcgtgccg ggcggtggga atacgatcgc gccgaacgcg
     7861 agctggtcgc ggcctttaac gccgtgcgta aggtgaaaac accgggcggc tttatcactt
     7921 acgaaacgga ccgcgcgagg gggatcagcc acggcgacct tgcgtgggca accatgcttg
     7981 ctgtcattaa cgaaccaatt ggcggcgaag gagaaaacga gcgtttcatg gttatggagt
     8041 tctgatgagc agaaaaaata aaaaagtgcg catgagttca cgcattgatc tcgctgatgc
     8101 gctcaggaaa gaatcatcgc tcagtgcatt cacatttgat ggtccttatc gcctgaccgg
     8161 gcatgacctg ctggacaata tgtactgtgc tgataacggg cggtggtatg aaaccccggt
     8221 ggactggtac ggtctggcaa gagcagcccg gcaaacgtcc tggcatcagt ctgcgcttta
     8281 ctttaagcgc aatgtattac tcggttgcta catcccgcac ccgctgcttt cccggcagga
     8341 tttctcggcg ctggcgctgg actggtttgt gttcggtaac gcattccttg agcttcgaag
     8401 caatatgctc ggcgaaccgc ttaaattacg gcacgccctg gcgaaataca tgcgacgcgg
     8461 aagcgatctt gaatcatggt ggtatgtgca ggatggcaag gacgcgtttc agtttcgtcc
     8521 tggcaaagtg tgccacctga tgaatccgga tattaaccag gaaatctacg gcatgccgga
     8581 atatcttggc gcattactct cggccagcct ttctcattcg gcggacatgt tcagaaaact
     8641 gtactacgac aacggatccc acgccgggtg catcatctac atcggtgcag cgcaggtaaa
     8701 ccgcgaaagc atggactccc tgaaagaaac gctacagggg gcacgtggtg gtggtgcgtt
     8761 taaaaacgtg ctcattcatg cgcccaacgg gggcaaagag ggggtgcaaa ttttgccgtt
     8821 ccagcagatc accgcaaaag atgaattcat gaatgttaag gcggcatccc gtgatgatgt
     8881 gctggctgcg caccgcgttc cgccgcaact gatgggggcg atgccgggcg aaaaaagtgc
     8941 gtttggcgat gtggagaagg cagcgcgggt ttacgcaatt aacgagctga tgcccgttat
     9001 ggaggctatg aagcacatca atgactggct tggcgaagag gtgatccgtt ttaactctta
     9061 tgctcttctt gatgaaaaaa cagccccgtg atggggctgt cctttttacc agagttgaac
     9121 cattttctgg gtgccgtcag gcttgagatt atcaatttca gagagaacgt aatattgaat
     9181 ggcttcacaa acggtggtgt agggtgaatt accttcttta agtggcacga tattattatt
     9241 aacgcgaacc tgtatttcat cgttatacat tgcgatcgaa acaggagtgt gcacgaacgc
     9301 gacttcgcca ggtgtgtcgt caaccaccgt ttcaatacta aaagtcagtt ttcgctcatc
     9361 attgctgccc cgtgctttgg gggtagcggc agggatctgg gataaaggca ttctgcgaaa
     9421 tccttcggct gcttccagtc cgcatgaaac gtaatgctgg cgattaccgt cgctatctgt
     9481 ccaggtctgt gatggcagct ccagcgagat ttcataagca tcaacaatgc cctgggcaag
     9541 gcgtacaagc ggggtcagat cttcattgcg gcgaaagctc tcctttacct gctcccgttt
     9601 ttctcttaac tgcttgtaat taatgaccat aagacagcct ccattgattt ctttgctcgt
     9661 attttgcact tatgaagtat ggtcggcaag gtgccgtatc gctgacgcgc ttcgcttgtc
     9721 tgctgcttcg ccggggcata aaaaatttat gccccggctc tccagctcct gtatcaatca
     9781 gataatttca cgacgccttc cagtttatcg ccaccatcga cggtcagact cttacgcaat
     9841 tccaccgcgt tgactgcatg ttctcgctgc ctcagtgcga ttttgacggc cttacctttc
     9901 accccatcaa atcaaaagcc ctcacgcctt tttcatgctc agcgtgagaa atatggccat
     9961 tctgttgtgt ctctgcgaca tcgttcaggg aatgctattt accccctgaa acgcgggctg
    10021 ttcccccgtc acctgcgcgc agaaaaagcg cgtttttttg tgcacgcacg gatccttgac
    10081 ggatccagcc gccatgcggg ccggaagggt aaaaagtcgt tcaaaaaaat tgtgcaaatt
    10141 tgtgcacttt tgtgcaggta agcatgccta tatatttgac cgtggcttgc ctttgatgta
    10201 gtttatacgt cacaaaaacc acaaaacgtg gttatgattt ctatgagggg gttgatatga
    10261 aaaaaatgta tgatgaattt gatggtttct aagctacgtt gacctctaat gaggcgggga
    10321 tttgctcccc gcctttttta tggatgaaat aggatgaacc caataacact acaaatcatc
    10381 agcaatgcta ttgttctgct tggcgttttg gttgccattg gaaccattat ctacaatgtg
    10441 cgtaccgcaa aaaaaactca aacggccaac tttctttttg agagtcggca agatatgcaa
    10501 tatatagagt cattgcatac cctgaaacaa gtgcatcgtt caggcaaatc atttcgttct
    10561 tatgtttttc cttgtgatgg ttgcataata acagatgaag aaatggccga gcgtcgaaaa
    10621 tttcaatata ttttaaattt ttacgagcga gttgctgtaa gtattcgtga aggtatttat
    10681 gatgaaaaaa tgataaaaag aacatcttac acaacagttg tagagacata tgatattgcc
    10741 gagccattaa ttaaagcaat cagagaaagc attaattcgg atactacata tcaagaattc
    10801 gaatggttag taagaagatg gaaagctaat cctttacgga aaaacaaata atgttttacc
    10861 ctttaattta caagtaacac agggggaagt gtgacacaga atccgttttc attttatgac
    10921 tttttgggct atctaattcc aggtgggtta ttcctgttta tccttttttt gttttctatt
    10981 gaaattaacc ctgtttatat agaaggtatt cttaaccata tcctgaaata taaagaaata
    11041 ataagtgtat ttatatatgt ggtattaatc gttctatcat atatttcagg tcacttcata
    11101 tctattctat catcctgttt aattg
//
LOCUS       DAPOXO010000128        11036 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.128, whole genome shotgun sequence.
ACCESSION   DAPOXO010000128 DAPOXO010000000
VERSION     DAPOXO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11036
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.128"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            23..853
                     /locus_tag="ROH59_004558"
     CDS             23..853
                     /locus_tag="ROH59_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX4806955.1"
                     /translation="MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGV
                     TIRGDLSYLEQQGYLKRSFGGAIATPLSSEPEAIQPIAPLSLAQQMEIARHCARLIRD
                     RDTLFLGHGTICRKIIPLLSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDT
                     ALAGKQLEQALQHFTITHSILEISHLDADGTLNINVPRLAAAWQLCFDHAQNKTVIVA
                     ADPAPSTAAIGHLHQAENVIVSRSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE
                     "
     gene            885..1820
                     /locus_tag="ROH59_004559"
     CDS             885..1820
                     /locus_tag="ROH59_004559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX4806956.1"
                     /translation="MGELLAEFLSRNPHQKFTQPGEFIGPFPSGAPAIFAAQVAKLSH
                     RAIFFGCVGNDDFARLIIERLRHEGVITDGIHVMNNAVTGTAFVSYQNPQLRDFVFNI
                     PNSACGLFTAEHIDKDLLKQCNHLHIVGSSLFSFRMIDVMRKAITTIKSAGGTVSFDP
                     NIRKEMLSIPEMAQALDYLIEYTDIFIPSESELPFFARHKNLSEEQIVSDLLHGGVKH
                     VAIKRAQRGASYYKLKNGTLHAQHVAGHDIEIIDPTGAGDCFGATFITLFLSGFPAHK
                     ALQYANASGALAVMRQGPMEGISSLADIEDFLQQH"
     gene            1913..2155
                     /locus_tag="ROH59_004560"
     CDS             1913..2155
                     /locus_tag="ROH59_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HDX4806957.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLPGVAPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVRFIYRDIPLEDDDAA"
     gene            2145..3596
                     /gene="panF"
                     /locus_tag="ROH59_004561"
     CDS             2145..3596
                     /gene="panF"
                     /locus_tag="ROH59_004561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HDX4806958.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVDTLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLAKLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            3608..4489
                     /gene="prmA"
                     /locus_tag="ROH59_004562"
     CDS             3608..4489
                     /gene="prmA"
                     /locus_tag="ROH59_004562"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDX4806959.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            4818..5783
                     /gene="dusB"
                     /locus_tag="ROH59_004563"
     CDS             4818..5783
                     /gene="dusB"
                     /locus_tag="ROH59_004563"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDX4806960.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            5809..6105
                     /gene="fis"
                     /locus_tag="ROH59_004564"
     CDS             5809..6105
                     /gene="fis"
                     /locus_tag="ROH59_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HDX4806961.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            6190..7074
                     /gene="yhdJ"
                     /locus_tag="ROH59_004565"
     CDS             6190..7074
                     /gene="yhdJ"
                     /locus_tag="ROH59_004565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDX4806962.1"
                     /translation="MRTGCEPTRFGNEAKTIIQGDALTELKKLPAESVDLIFADPPYN
                     IGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLF
                     TIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
                     NYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIV
                     LDPFAGSFTTGAVAVASGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTG
                     NLSKRSRLSEVDPDLIAK"
     gene            7158..7337
                     /locus_tag="ROH59_004566"
     CDS             7158..7337
                     /locus_tag="ROH59_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HDX4806963.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNP
                     LKLVNCDELNFQDRM"
     gene            complement(7340..8002)
                     /gene="acrS"
                     /locus_tag="ROH59_004567"
     CDS             complement(7340..8002)
                     /gene="acrS"
                     /locus_tag="ROH59_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HDX4806964.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQDHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
                     VVMIIIDGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHKTNELS
                     VI"
     gene            8401..9558
                     /gene="acrE"
                     /locus_tag="ROH59_004568"
     CDS             8401..9558
                     /gene="acrE"
                     /locus_tag="ROH59_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HDX4806965.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQA
                     SYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
                     ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQS
                     SNDFMRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLR
                     AVFPNPQHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNNKSQVEAR
                     PVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
     gene            9570..>11036
                     /gene="acrF"
                     /locus_tag="ROH59_004569"
     CDS             9570..>11036
                     /gene="acrF"
                     /locus_tag="ROH59_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HDX4806966.1"
                     /translation="MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVS
                     VSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDI
                     AQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVAS
                     NVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ
                     LGGTPALPGQQLNASIIAQTRLKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN
                     VIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ
                     LSIQEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPREATEKSMSQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILT"
BASE COUNT         2729 a         2683 c         2790 g         2834 t
ORIGIN      
        1 tagtgttacg cattaaaggc caatgaagag tgttaacgtg ccgagaaaat cgtctaactt
       61 actgaaacgt agattaaaaa ttgcagaaat tgttgccgcc cagggtgaaa tcaaagttga
      121 tgacttatct gcgcaacttg gtgtctctgg cgtgacgatc cgcggcgatc tcagttatct
      181 ggagcaacag ggatatttaa agcgatcatt tggcggtgct attgcgacac cactctcctc
      241 tgaaccagaa gcgatacaac cgatcgcgcc attgtctctg gcacaacaaa tggaaatagc
      301 acgacattgc gcacggttaa ttcgcgatcg tgacacgcta tttcttggac atgggacaat
      361 ctgccgtaag atcattccat tgctcagcga agtgaaaaaa ctgcgtctga tcaccaacga
      421 tcccgaacat gcgctgctgg caaatcagtt tattgatggc gaaataatac tggctggcag
      481 tgaaatgctg cgccccgaca ccgcactggc cggaaaacag cttgaacagg cacttcagca
      541 tttcaccatt acacatagca ttctggaaat cagccatctg gatgctgatg gtactttaaa
      601 tatcaacgtt cccagactcg ccgctgcctg gcagctctgt ttcgatcatg cccagaataa
      661 gacggttatc gttgccgccg atcctgcgcc atcaacggct gctatcgggc atttgcatca
      721 ggcagaaaat gtgatcgtca gccgcagcat taacgaacaa tatcagcaac aattgcagtc
      781 ggctgatttc gttatccttt ataccagtaa tgagtgcttt acctggtcca atcgcgaaag
      841 gcttcaggaa tgagaggggt tttgtgacaa taactatctg cgctatgggc gaattgctgg
      901 ccgagttttt gtcccgcaac ccacatcaaa aattcactca gcctggggag tttatcgggc
      961 catttcccag cggtgcgcca gcaatttttg ctgctcaggt ggcaaaactg tcccatcggg
     1021 ccatcttctt tggatgtgtt ggtaatgatg attttgcccg actcattata gagcgtctcc
     1081 gtcatgaagg tgtcattacc gatgggatcc atgttatgaa caatgccgtc acaggtacgg
     1141 cgttcgtgag ttatcaaaat ccccagctgc gggatttcgt ctttaatatc cctaacagcg
     1201 cctgcggttt gtttactgcc gagcacattg ataaggatct gcttaaacag tgtaaccatc
     1261 tgcatattgt gggctcatcg ttgttctcat ttcgcatgat cgatgtcatg cgtaaagcaa
     1321 taacgacgat caaatcggct ggcggcaccg tttctttcga tcccaatatt cgcaaagaga
     1381 tgctgagcat tcctgaaatg gcgcaggctc tcgattattt gattgaatat acggatattt
     1441 ttatccccag cgaaagcgaa ctccctttct tcgcgcgtca caaaaatctg tcagaggaac
     1501 agattgttag cgatcttctc cacggcggcg taaaacatgt ggcgataaaa cgcgcccagc
     1561 gtggggctag ctattacaag cttaaaaacg gtacattaca cgcccagcat gttgcaggtc
     1621 acgatatcga aattatcgat ccaacgggtg caggcgactg ctttggcgca acgtttatca
     1681 ctcttttctt atccggtttc ccggcacaca aggcgctgca atatgcaaat gccagcggcg
     1741 cgctcgccgt aatgcggcaa ggtccgatgg aagggatatc ctcactggca gacattgaag
     1801 actttttgca gcagcactga acggcaattt tctgtcagat tattttccct gcctgaagac
     1861 ttgccgtaga attgcccgtt tctcgtatcc ccccatgagg aggacccctt ccgtggacac
     1921 tcgttttgtt caggcccata aagaggcgcg ctgggcgctg gggctgaccc ttttgtatct
     1981 ggcggtatgg ttagtagccg cttacttacc tggcgttgcc cccggtttta ccggttttcc
     2041 gcgctggttt gagatggcct gcatcctgac gccgctgctg tttattggac tgtgctgggc
     2101 gatggtgaga tttatctatc gcgatatccc actggaggat gacgatgcag cttgaagtaa
     2161 ttctaccgct ggtcgcctat ctggtggtgg tgttcggtat ctctgtttat gcgatgcgta
     2221 aacggagcac tggcaccttc cttaatgagt atttcctcgg cagccgctct atgggcggta
     2281 ttgtgctggc gatgacgctc accgcgacct atatcagtgc cagttcgttt atcggcgggc
     2341 ctggagctgc ttataaatac ggcctgggct gggtattgct ggcgatgatt cagcttcctg
     2401 cagtctggct ttcgctcggt attctcggca agaagttcgc aattcttgcg cgccgctaca
     2461 atgcggtgac gctgaacgat atgctgtttg cccgctacca gagtcgtctt ctggtgtggc
     2521 tggcgagttt gagtttgctg gttgcgttcg ttggtgcgat gaccgtgcag tttatcggcg
     2581 gtgcgcgcct gctggaaacc gcggcgggta ttccttatga aaccgggctg ctgattttcg
     2641 gtatcagcat tgcgttgtat accgcctttg gcggctttcg cgccagcgtg ctgaacgaca
     2701 ccatgcaagg gctggtgatg ctgattggca ccgttgtgct gcttattggc gtggtacatg
     2761 ccgcaggtgg tttaagtaat gcggtagaca cgctgcaaac catcgatccg caactggtta
     2821 cgccacaagg cgctgacgat attctgtcgc ctgcctttat gacgtcgttc tgggtactgg
     2881 tgtgctttgg cgttataggc ctgccgcata ctgcggtgcg ctgtatctct tataaagaca
     2941 gcaaagcagt acatcggggg atcatcatcg gtacgattgt agtcgcaatc ctgatgttcg
     3001 gtatgcatct ggccggagcg ttaggtcggg cggtgatccc cgatctcacc gtaccggatc
     3061 tggtgatccc gacgttaatg gtaaaagtgc tgccaccgtt tgccgccggg atcttcctgg
     3121 ctgcaccgat ggctgcgatc atgtcgacaa ttaacgccca actgctgcaa agttccgcta
     3181 cgatcattaa agatctctat ctgaatatcc gtccggatca aatgcaaaac gagacgcgtc
     3241 tgaagcggat gtcggcggtg atcacgttgg ttctcggtgc gttgctgctg cttgccgcct
     3301 ggaagccgcc agaaatgatc atctggctga atttgctggc cttcggtggg ctggaagccg
     3361 ttttcctgtg gccgctggtg ctgggtcttt actgggaacg cgccaacgcc aaaggcgcgc
     3421 taagtgcgat gatcgttggc ggcgtgctgt atgccgtact cgcgaagctg aatattcagt
     3481 acctgggctt ccaccctatc gtgccctcgt tactactaag tttgctggct ttcctggtcg
     3541 gaaaccgttt cggtacatcc gtcccgcaag ctaccgtttt gactactgat aaataaagag
     3601 ttttgccatg ccttggatcc aactgaaact gaacaccacc ggcgcaaacg cggaagatct
     3661 tagcgatgcg ctgatggaag cgggtgccgt ttctatcact tttcaggata cccacgatac
     3721 gccagtattt gagccgctgc cgggcgaaac gcgcctgtgg ggcgacaccg atgtgattgg
     3781 tctgttcgac gctgaaaccg atatgaacga cgtggtggcg attctggaaa accatccgct
     3841 gctcggcgcg ggcttcgcgc ataaaatcga acaactggaa gataaagact gggagcgcga
     3901 atggatggat aatttccacc cgatgcgctt tggtgaacga ctgtggatct gcccaagctg
     3961 gcgtgatgtg ccggacgaaa acgccgtcaa cgtgatgtta gacccagggc tggcgtttgg
     4021 tacgggtacc catccaacta cctctctgtg cctgcaatgg ctcgacagcc tcgatttaac
     4081 cggtaaaaca gtcatcgact ttggctgcgg ttccggcatt ctggctatcg cggcgctgaa
     4141 actgggtgca gcaaaagcca ttggtattga tatcgatccg caggcgatcc aggccagccg
     4201 cgataacgcc gaacgtaatg gcgtttctga tcgtctggaa ctctacttac cgaaagatca
     4261 gccagaagaa atgaaagccg acgtggtggt cgctaacatc cttgcaggcc cattacgtga
     4321 actggcaccg ttaatcagcg tcctgccagt ttcaggcggt ttgctgggcc tttccggtat
     4381 tctggcaagc caggcagaga gcgtttgcga agcttatgcc gacagcttcg ctctggaccc
     4441 ggtcgtggaa aaagaagagt ggtgccgcat taccggtcgt aagaattaac cttcgcatcg
     4501 ccgtatggcg acgcagagcg aagtgcgagc gatgtcacaa aaggcacgtt aatttgccga
     4561 ttatttacgc aaatttgcgt gccaaaattt tcattcataa agaaaaattg agaacttact
     4621 caaatttctt tgagtgtaaa ttttagtcac tattttctaa tatgatgatt tttatgagta
     4681 attatcgcgc tacgctcatt ttaaatgcaa ttctttgatc catctcagag gattggtcaa
     4741 agtttggcct ttcatctcgt gcaaaaaatg cgtaatatac gccgccttgc agtcacagta
     4801 tggtcatttc ttaactcatg cgcatcggac aatatcagct cagaaatcgc ctgatcgcag
     4861 cgcccatggc tggcattaca gacagacctt ttcggacgtt gtgctacgag atgggagccg
     4921 gattgacagt atccgagatg atgtcttcta acccacaggt ttgggaaagc gacaaatctc
     4981 gtttacggat ggtgcacatt gatgaacccg gtattcgcac cgtgcaaatt gctggtagcg
     5041 atccgaaaga aatggcagat gcagcacgta ttaacgtgga aagcggtgcc cagattattg
     5101 atatcaatat gggttgcccg gctaaaaaag tgaatcgcaa gctcgcaggt tcagccctct
     5161 tgcagtaccc ggatgtcgtt aaatcgatcc ttaccgaggt cgtcaatgca gtggacgttc
     5221 ctgttaccct gaaaattcgc actggctggg caccggaaca ccgtaactgc gaagagattg
     5281 cccaactggc tgaagactgt ggcattcagg ctctgaccat tcatggccgt acacgcgcct
     5341 gtttgttcaa tggagaagct gagtacgaca gtattcgggc agttaagcag aaagtttcca
     5401 ttccggttat cgcgaatggt gacattactg acccgcttaa agccagagct gtgctcgact
     5461 atacaggggc ggatgccctg atgataggcc gcgcagctca gggaagaccc tggatctttc
     5521 gggaaatcca gcattatctg gacactgggg agttgctgcc cccgctgcct ttggcagagg
     5581 ttaagcgctt gctttgcgcg cacgttcggg aactgcatga cttttatggt ccggcaaaag
     5641 ggtaccgaat tgcacgtaaa cacgtttcct ggtatctcca ggaacacgct ccaaatgacc
     5701 agtttcggcg cacattcaac gccattgagg atgccagcga acagctggag gcgttggagg
     5761 catacttcga aaattttgcg taaacagaaa taaagagctg acagaactat gttcgaacaa
     5821 cgcgtaaatt ctgacgtact gaccgtttct accgttaact ctcaggatca ggtaacccaa
     5881 aaacccctgc gtgactcggt taaacaggca ctgaagaact attttgctca actgaatggt
     5941 caggatgtga atgacctcta tgagctggta ctggctgaag tagaacagcc cctgttggac
     6001 atggtgatgc aatacacccg tggtaaccag acccgtgctg ctctgatgat gggcatcaac
     6061 cgtggtacgc tgcgtaaaaa attgaaaaaa tacggcatga actaattcag gttagctaat
     6121 tgcttgatta aaaggcgcta ctcggcatgg ggaagcgcct tttttatagg tgtcacaaag
     6181 ggagtgacca tgagaacagg atgtgaaccg acccgatttg gtaatgaagc aaagaccatc
     6241 atccagggtg atgcattaac cgaacttaaa aagctccccg ccgaaagtgt cgatctgatc
     6301 tttgccgacc caccgtataa catcggtaaa aattttgatg gtctgatcga agcctggaaa
     6361 gaagatctgt ttatcgactg gctgtttgaa gtgattgcag agtgccatcg cgttctgaaa
     6421 aagcagggca gcatgtacat catgaatagc acggaaaaca tgccctttat cgatctccag
     6481 tgccgcaagc tttttaccat caaaagtcgc atcgtctggt catatgacag ttctggagtg
     6541 caggcgaaaa aacactacgg ctccatgtac gaacccatcc tgatgatggt gaaagacgca
     6601 aagaactaca cgttcaacgg tgatgctatt ctggtagaag ccaaaaccgg atcgcagcgc
     6661 gcgttgatca attatcgcaa aaatcctcca cagccttaca atcatcaaaa agtaccgggt
     6721 aacgtctggg attttccgcg cgtgcgttat ttgatggatg aatatgaaaa ccacccgacg
     6781 caaaaaccgg aagccttgct gaaacgcatt attctcgcct cttccaaccc aggcgatatc
     6841 gttctcgacc cgtttgccgg tagctttact accggtgccg tagccgtcgc cagcgggcga
     6901 aaattcattg gtattgagat caacagcgag tacatcaaaa tggggcttcg acggctggat
     6961 gtcgcgtcgc attactctgc ggaagaactg gcgaaagtga aaaaaagaaa gaccggcaac
     7021 ctgtcaaaac gaagccggtt aagcgaagtt gaccccgatc tcattgcaaa gtaaaggaag
     7081 tgtaagcctg gttttcagat tattcatttc gtgtatattt cctgccagac ttggttaaac
     7141 atgcacaggc tcaggtaatg attcgcaagt attggtggct cgtcgttttc gctgtcttcg
     7201 tttttctgtt tgatacttta ctgatgcagt ggattgaact gctggcaaca gaaacagaca
     7261 aatgccgcaa tatgaactca gttaatccac taaaactggt taactgtgac gaactgaatt
     7321 ttcaggacag aatgtgaatt tatatgacac ttaattcatt cgttttatga attaatttcg
     7381 ttatgttttc atctggcatg aacattctta atacgttatc gaccagagcg ggggcttgtt
     7441 tataaagatc ataacccgcc atattcatta accagttttg aacaattccg ctgaaggcac
     7501 catcaataat aatcatcaca acatctaaat cgagattatt tgctacacaa ccttgttgct
     7561 gacacgcctg caatacttcg cggagagtct gcggattaaa gcccatcttt tcgcgtatca
     7621 ctccctcggc cagcatctca tcattaaatt cacatttgtg atataagatt ttcagcaacg
     7681 cctgctggcg gggaattttg gcaatatatt gcaaaccgac aatcaatttt tcacgcaatt
     7741 gctgaaacgg gtcatgctct aacccagcgg tcaagtgatc ctggattaac tcccgcaatg
     7801 aaggctgttg caaccacatc tcattaaaca gttgagtctt gttttcgaag tgccagtaga
     7861 tagcgccacg cgtaacgtta gcagcgtcgg caatgtcgtt gagcgtcgtc ttgcttacgc
     7921 catgctgcgc aaactgggcg atggcagttt caatcagttc ttgccgggtc ttcagggctt
     7981 cagctttggt tctttttgcc atgattaatt attcaggaaa taaatatatt cgacacagga
     8041 tgagaaaata gcgaaggtta atctatcacc taatgtgtat ttatacgaga ggctaatatt
     8101 gcgttgctat aaatcgtcaa ataaatgata tgtattattt acataaaata cattcacttg
     8161 acctatacat atttcaattt acgagatttt aattctattt ctttcattcc gcgtcaaaac
     8221 aaaacagtag aatattaatc tttttttgtg tttatgtgcc ttgagttgcc agtattcata
     8281 actattcctt acatcgacga atgataattt gtaggatagc gaactgtatt tttctttctg
     8341 cgagttaacg cattgccttt ttgggcaaat aacgcgcttt tggttttttg aggaatagta
     8401 atgacgaaac atgccaggtt tttcctcctg ccctccttta ttctgatctc cgcggcttta
     8461 atcgccggtt gtaacgataa gggagaagag aaagctcacg tcggtgaacc gcaggttacc
     8521 gttcatattg tgaaaacggc cccgttagaa gttaagactg aattaccagg ccgcaccaat
     8581 gcttaccgta tagccgaagt tcgcccacag gttagcggga tcgtactgaa tcgcaatttc
     8641 actgaaggca gcgatgtgca agcaggccag tccctgtacc agatcgatcc cgcgacctat
     8701 caggcaagtt atgacagcgc gaaaggcgaa ctggcgaaaa gtgaagccgc cgccgccatc
     8761 gcgcatttga cggtaaaacg ttacgttccg ctcgtgggta cgaaatacat cagtcagcag
     8821 gagtacgacc aggccattgc tgatgctcgc caggccgatg ccgccgtgat tgccgcaaaa
     8881 gccacagtcg aaagcgctcg catcaatctc gcttatacca aagtgactgc gccaattagc
     8941 ggacgtatcg gcaaatcgac cgtgaccgaa ggcgctcttg tcactaatgg gcaaacgact
     9001 gaactggcga ctgtccagca gctcgatcct atctacgttg atgtgaccca atccagcaac
     9061 gattttatga ggctgaagca atccgtagag caaggaaatt tgcataagga aaacgccacc
     9121 agcaacgtag agttggtcat ggagaacggt caaacctatc ccctgaaagg tacgctgcaa
     9181 ttctccgatg tgaccgttga tgaaagcacc ggctccataa ccctacgtgc tgtcttccct
     9241 aacccgcaac atacgctttt gccgggtatg tttgtgcgcg cacggattga tgaaggcgtc
     9301 caacctgacg ccattcttat cccgcaacaa ggcgttagcc gcacaccacg tggtgatgca
     9361 accgtgctga ttgttaacaa taaaagtcag gttgaagcgc gccctgtcgt tgccagtcag
     9421 gcgattggcg ataaatggtt gattagcgaa ggtctgaaat ctggcgatca agtcattgtc
     9481 agcggcctgc aaaaagcgcg tccgggagag caggttaaag ccactaccga tacccccgca
     9541 gatactgcat cgaagtaagg caatctgaca tggcaaactt ttttattcga cgaccgatat
     9601 ttgcatgggt gctggccatt attctgatga tggcgggcgc actggcgatc ctacaattgc
     9661 ccgtcgccca gtatccaacc attgcgccgc ctgcggtttc tgtttcggca aactatccgg
     9721 gtgctgatgc gcagaccgtg caggatacag tgacgcaggt tatcgaacag aatatgaacg
     9781 gtatcgataa cctgatgtat atgtcctcca ccagcgattc cgccggtagc gtgacaatta
     9841 cccttacctt ccagtccggg accgatcctg atatcgcgca agtacaggtg cagaacaaac
     9901 tccagctcgc cacgccgttg ctgccgcagg aggttcagca gcaggggatc agtgttgaaa
     9961 agtccagtag cagctatttg atggtggcgg gctttgtctc tgataaccct ggcaccacac
    10021 aggacgatat ctcggactat gtggcctcta acgttaaaga tacgcttagc cgtctgaatg
    10081 gcgtcggtga cgtacagctt ttcggcgcac agtatgcgat gcgtatctgg ctggacgccg
    10141 atctgctaaa caaatataaa ctgacaccgg ttgatgtgat taaccagttg aaggtacaga
    10201 acgatcagat cgctgccgga cagttgggcg gaacgccagc gttaccaggg caacagttga
    10261 acgcctcgat tattgctcag acgcggttaa aaaatccgga agaattcggc aaagtgaccc
    10321 tgcgcgtaaa cagtgacggc tcggtggtgc gtctgaaaga tgtcgcacgg gttgaacttg
    10381 gcggtgaaaa ctataacgtt atcgctcgca tcaacggaaa accggcggcg ggcctgggga
    10441 ttaagctggc aaccggcgcg aatgctctcg ataccgcgaa agccattaag gcaaaactgg
    10501 cggaattaca gccattcttc ccgcagggaa tgaaggttct ttacccttat gacaccacgc
    10561 ctttcgtcca gctttctatc caggaagtgg tgaaaacgct gttcgaagcc attatgctgg
    10621 tgttcctggt gatgtatctg ttcttgcaga acatgcgggc aacattgata cccaccattg
    10681 ctgtacctgt cgtgttgtta gggacatttg ccatactcgc cgcttttggt tactccatca
    10741 atacgctaac gatgtttggg atggtacttg ccatcggact tcttgttgat gatgcgatag
    10801 tcgttgtgga gaacgtcgag cgcgtaatga tggaggataa actccccccc agagaagcga
    10861 cggaaaaatc gatgtcgcaa atccagggcg cgctggtagg tatcgcgatg gtactgtcgg
    10921 cggtatttat tccgatggca ttcttcggtg gctcaacagg ggcaatttat cgccagttct
    10981 ctatcactat tgtttcagca atggcgcttt cagtactggt tgcgctgatt ctcacc
//
LOCUS       DAPOXO010000129        10935 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.129, whole genome shotgun sequence.
ACCESSION   DAPOXO010000129 DAPOXO010000000
VERSION     DAPOXO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10935
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.129"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1569)
                     /locus_tag="ROH59_004570"
     CDS             complement(<1..1569)
                     /locus_tag="ROH59_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein VasK"
                     /protein_id="HDX4806967.1"
                     /translation="MTVAVVVALCTFIHRKPALLGVEPGSSQQMYWMAGVIAAGVVFL
                     IIMGVYHLLNRHAAVQNFELRRQLAAGDDYRAVTTKKADSRHPAMVELAAFLRDRYGP
                     FWRRKIRLLLVTGEPEQAEAIAPGLTGQHWLEGDHTVLIYGGRPSAEPDVALLTALKK
                     LRRSRPLDGIIWPLTEEQSRQTAQLDKGWRELINGGKRLGFQAPFYLWQVCDNGDYQS
                     GRVLQSVGCLLPEGCTPEQLAAMLEAQTLPLTEQGMSQLLTDNRHDFLLRLAHTLAER
                     GITHWQTVLKPLLAGGAFSSLRLRGLMFSPPLAAVPEAAPHAWLPSPVWAGITGDNAR
                     GRAVGFPWLRTALMSAVCVLAIGGAGMTTSFFANRALVQETSIQTARALDTRLPLAEQ
                     LVALHTLQGELERLQYRIREGAPWYQRFGPERNQQLLAAAFPGYAQAANRLVRDVAVD
                     HLQQQLNAFVALPPNSPQRTATGEQRYKQLKALLMTSRPEKADAAFFSTTLMADGLRY
                     ENIPEGVRQSVLPSL"
     gene            complement(1626..2840)
                     /locus_tag="ROH59_004571"
     CDS             complement(1626..2840)
                     /locus_tag="ROH59_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806968.1"
                     /translation="MPVRLNTIPDAEPYPVPPARIKWLTALLLMLSVGVALTSLFASD
                     ELAKNGPYFWGLACGVPAFIWSLVASVRWLFFITQYIRTDAWNKRREEVILQETRRGR
                     RALQILSFSVQTALNGDSVAETITAFLARQQVLNTYADLRGEDTVRRSVIPVLTNKPV
                     TGRLSEVFSRLFSDIRLQLTRLPDDFHINVLLEIDAPLSGASVRTIWQDEWQKAGLPE
                     ARLFSAPEPGLAAVDDWLDNHIQEKAVLLVISVRLEPKNPERTAESATALLLANRLTQ
                     TALTPLALLHRPECITDTEMMASGIAQALDWMPVQPDAISGMWTAELDREQRAALLSL
                     NQPFAQEALMYELDAFLGRSGPAAPWLSVAVATLAAIQSQHPQLTLSGVQGGHYSWAT
                     VVSPFVSPQEAS"
     gene            complement(2918..3367)
                     /locus_tag="ROH59_004572"
     CDS             complement(2918..3367)
                     /locus_tag="ROH59_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001378343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806969.1"
                     /translation="MQLLSLRTIDGDTLYLKFRNVITGAFLDTPTKSYDFFGDVVLSQ
                     CINGSLIFALEYGSPYIKGCLVTGWENGFKGKNSPEGFCFAERNIPEAVWFGKNNILI
                     IIRNQMDVGTWKGKYIIYDNAKKSGERAYSSDNLPSKDGYIIFALNK"
     gene            complement(3470..4072)
                     /locus_tag="ROH59_004573"
     CDS             complement(3470..4072)
                     /locus_tag="ROH59_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDX4806970.1"
                     /translation="MADKSEKKKETTNKSAKKTLTKKSEKLTPAKDTAPKQVNVDPAI
                     RLKQIRQLVRNNNKSIMGEDYIICQIYKESRFKQFAGKNKHNAKGLMQMQRNAVRQVF
                     KYRQQKIKGRMTTDKETNEAFANADTFYKSDKIFDEKENIKIGTEYLQYWIDKEATIE
                     EAYRTYRGTDEAYYSVIKPCAEKLAKDPDNIQILMEGIGR"
     gene            complement(4094..6607)
                     /gene="vgrG"
                     /locus_tag="ROH59_004574"
     CDS             complement(4094..6607)
                     /gene="vgrG"
                     /locus_tag="ROH59_004574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX4806971.1"
                     /translation="MDIPTLNFDHSHHKLKIRGLKSPADVLTFTGHEQLSSPFRYDIE
                     FTSTNKAITPESVLMQDGAFSLTAPPVQGMPVQTALRTLHGVITSFKHLSSSQDEARY
                     EVRLEPRMALLTRSRQNAIYQNQTVPQIVEKILRERHQMRGQDFVFNLKNEYPAREQV
                     MQYGEDDLTFVSRLLSEVGIWFRFATDARLKIEVVEFYDDQSGYERGLTLPLRHPSGL
                     FDGETEAVWGLNSAYSVVEKSVSTRDYNYREATAEMTTGQHDATGGDNTTYGEAYHYA
                     DNFLQKGDKEAAESGAFYARIRHERYLNEQAILQGQSTSSLLMPGLEIKVQGDDAPAV
                     FRKGVLITGVTASAARDRSYELTFTAIPYSERYGYRPALIPCPVMAGTLPARVTSTVK
                     NDIYAHIDKDGRYRVNLDFDRDTWKPGYESLWVRQSRPYAGDTYGLHLPLLAGTEVSI
                     AFEEGNPDRPYIAGVKHDSAHTDHVTIQNYKRNVLRTPANNKIRLDDERGKEHIKVST
                     EYGGKSQLNLGHLVDAGKQQRGEGFELRTDLWGTVRAKKGIFISSDAQDKAQGKVREM
                     APAMAILDGAQSQMKSLSTDAQTANADPADLSSQIALLQQSVKDLTQAAILLSAPKGV
                     AIASGEHLQLAASKNLIANAGNHADIGVVKNMFIGVGQALSVFVRKAGIKLFANKGAI
                     SVQAQNDLMELLAQKSIEITSTEDEIKITAKKKITLNGGGSYIRLDACGIEAGTPGEY
                     NVKAGYYGRKPKAKLTPELMAFPVIKSEDFNQSFILLDENTGQPLINWPYELELESGL
                     KMSGITDENGNTELISSDKEEVVNISVFEPDEFLDDEIN"
     gene            complement(6713..8581)
                     /locus_tag="ROH59_004575"
     CDS             complement(6713..8581)
                     /locus_tag="ROH59_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2235 domain-containing protein"
                     /protein_id="HDX4806972.1"
                     /translation="MISESVISAAVRAQQSEDGKVGNCGRIWHVAFFFDGVGRNIDRD
                     ATDCRLSNIARLFRAYPDEQKNTGDTCYNKFYFSGMGTAYHDDSVDNIHALMDIGLDN
                     FLEDMKSLPEDTISDAGESVIKGEKKWTDVLGNLLEDLNNPVEWVKGIGKMAAKSVGK
                     AGIESTPWLRDSEAMSAYFMTGEPVRLEAAKRLFKKFYTENMKGDVPIKKISVSLYGF
                     DLGATLARKFLDNFLKEVCLKNKEKKHQYKNALVDIAFIGLFDCSRHSPTSSNNGLDY
                     FFMWLGLPGKMIGSVLGEKAIDQDSPLPDVVNNALHLVAAHERRPWRGLYLLGKKTDT
                     ANKKYREELLPGCSEDIGGGLKPDEQKPSAELCRVALYNMYHAACQAGVPFPDFDTLD
                     QYDTKVASYFIMNDAVQGGSVNYWVSRYQREEVKDKVFSEAMQEKYLDNYFLWLGEQY
                     YMYQYERERLDKELTSAHRGKISDYGPLAGTGINPNTNADDIKSQISELDSLWGWLND
                     VKSVAIGLRNDFIVNPRKNDSRIKLKPQVYNAAVNRAVKFLEFSRAVYNDKNLPSSSS
                     LTANTLYSFFVHDIQKVDHTPSISEDFFLRRSSEIPDADEPPGNKDDGKKHTRRDD"
     gene            complement(8578..9105)
                     /locus_tag="ROH59_004576"
     CDS             complement(8578..9105)
                     /locus_tag="ROH59_004576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3304 domain-containing protein"
                     /protein_id="HDX4806973.1"
                     /translation="MGLFTRLEKFDQKLTRGYARWGRWVWRMLIAIPVAYFLLCVGIS
                     IWGAPTGGVILVIHSELDRPILGFSVNGMAGANAFAHGGGSTTCCGDIRGKEAEVVWT
                     LSTTRAQYNTGLREEVRRITLPLPERKHGQDFLHVHFLPGDKVFLGWSEGAGSPYEKR
                     KEPSYPSRKNQEAQP"
     gene            complement(9149..9970)
                     /locus_tag="ROH59_004577"
     CDS             complement(9149..9970)
                     /locus_tag="ROH59_004577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4123 domain-containing protein"
                     /protein_id="HDX4806974.1"
                     /translation="MSSEQQLADHWLKRNETLNAFILFEGGALSQEMLQIMMEHYKYR
                     RISLYQLPDLKKVAAYGPWLVRIESEKDLAMVLVGKLPVAGITFSELQLEPLASRLAV
                     GCMAKTPDGREVLLRYYTPRVLKQLAARPDMDWHPVMFSQIESWWMLEDTRWQRLNMP
                     LTVANNSDETVEIITLDEPLWQKIADRGDVSALLREWRTMKTSEHFPPCIQRNMVEKA
                     LNKAQVVGLTKPLDQKIYALSYLNGKKAYLESAEFQVMLEKVKRNEISLSDLGRQ"
     gene            complement(9973..10929)
                     /locus_tag="ROH59_004578"
     CDS             complement(9973..10929)
                     /locus_tag="ROH59_004578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020235731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2345 domain-containing protein"
                     /protein_id="HDX4806975.1"
                     /translation="MTIQNYKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQLNL
                     GHLVDAGKQQRGEGFELRTDLWGAVRAKKGIFISADAQDKAQGQVREMADIISELNSL
                     SDKIQKLSDDAATANADPADMAAQIALITSRINDLTASVILMHAPKGVAVASGEHLQL
                     AAVKNLQINAGNNADIGVVKNMFIGVGRALSVFVRKAGIRLIANKGAVSVQAQHDLME
                     LLAKKSIEIVSTEDEIKITAKKKITINGGGSYIRIEGSGIEPGTPGDYNVKAVHYGRQ
                     PKASEKVPMPEFPILSAVDSSDFCLECLLNAIKNDDAVVEGV"
BASE COUNT         2514 a         2958 c         2524 g         2939 t
ORIGIN      
        1 cagtgacggc aacacgctct gccgcacgcc ttccgggata ttttcatagc gcaggccgtc
       61 tgccatcagc gtggtactga aaaaggcagc gtcggccttt tccgggcggg aagtcatcag
      121 caatgcctta agctgcttat agcgttgttc accggtggcg gtacgctgag gactgttggg
      181 cggcagggcg acaaaggcgt tcagttgctg ttgcagatgg tcaacggcca cgtcgcgcac
      241 cagccggttt gccgcctgcg catagccggg aaaggcggcg gcgagcagtt gctggttacg
      301 ttcagggcca aaacgctgat accacggcgc accttcgcgg atacggtatt gcaggcgttc
      361 cagttcgccc tgcagggtat gcagcgccac cagttgttct gccagcggca ggcgggtatc
      421 gagcgcccgc gccgtctgga tgctggtttc ctgaacaagt gcgcggttgg cgaagaacga
      481 ggtcgtcatt ccggcccccc ctatcgccag cacgcagaca gcggacatca gtgcggtacg
      541 cagccacgga aagcccaccg cgcggccccg cgcgttatcg ccggtgatgc ctgcccagac
      601 cggcgacggc agccacgcat gaggtgcggc ctccggtacg gcggcaagcg gcgggctgaa
      661 catcaggccg cgcaggcgca gggaagaaaa tgcgccgcct gccagcagcg gtttcaggac
      721 ggtctgccag tgggtgatac cccgctctgc aagggtatgg gccagacgca gcagaaaatc
      781 atggcggtta tcggtcagca gctgcgacat gccctgttcc gtcagcggta gggtctgtgc
      841 ttccagcatt gcagccagtt gttccggggt acagccttcc ggcagcaggc agccgacgct
      901 ttgcaggacg cgcccggact gataatcacc gttgtcacag acctgccaca aatagaatgg
      961 ggcctgaaaa ccgagtcgct taccgccgtt tatcagttcg cgccagcctt tgtcgagttg
     1021 cgctgtctgg cggctctgtt cttctgtcag cggccagatg atgccgtcca gcggacggct
     1081 gcggcgcagt ttttttaagg cggtcagtag cgcgacatca ggctccgctg atggcctgcc
     1141 gccgtatatc agcaccgtgt ggtcgccctc cagccagtgt tgcccggtca gccccggcgc
     1201 gatggcctct gcctgttcag gctcgccggt caccagcagc aggcggattt tacgccgcca
     1261 gaatgggccg tagcggtcgc gcaggaaggc ggcgagttcc accattgccg gatgacggct
     1321 gtcggctttc tttgtcgtca ccgcacgata gtcatctccg gcggcaagct gtctgcggag
     1381 ttcaaagttc tgcacggcag cgtggcggtt cagcagatga taaaccccca tgataatcag
     1441 aaagaccacg cctgcggcaa tcacgccagc catccagtac atttgctgtg agctacccgg
     1501 ttcaacgccc agcaatgccg gtttacggtg aataaacgtg caaagcgcaa ccacaacagc
     1561 cacggtcatg acgatggcag gccctgaaac cgaacggggc cggagacggt ttaatcccgg
     1621 aaccactatg atgcctcctg aggggaaacg aatggcgaca ccacggtcgc ccatgaataa
     1681 tgcccgccct gaacgccgct gagcgtcagt tgggggtgtt gtgattgtat tgccgccagc
     1741 gttgccacag cgacggacag ccacggcgca gccggtccgg agcgccccag aaaggcatcc
     1801 agctcgtaca tcagggcttc ctgagcaaac ggctggttca ggcttaacaa cgcggcacgc
     1861 tgttccctgt ccagttcggc agtccacata ccggatatgg catctggctg caccggcatc
     1921 cagtccagcg cctgtgcaat gcctgacgcc atcatctctg tatcagtgat acattcagga
     1981 cgatgcagca gggccagcgg cgtcagcgcg gtttgcgtca accggtttgc cagcaacagc
     2041 gcggtggcgg attctgccgt ccgttccggg ttcttcggtt ccagacgcac ggaaatcacc
     2101 agcagtacgg ccttttcctg aatgtggttg tccagccagt cgtccacggc ggccagcccc
     2161 ggctccgggg ctgaaaacag acgggcttcc gggagtccgg ctttttgcca ttcgtcctgc
     2221 cagatagttc tcacggaggc ccctgaaagc ggcgcatcaa tttccagtag tacgttgata
     2281 tgaaaatcat cgggtagccg cgtcagttgc agcctgatat cgctgaacag acgggaaaaa
     2341 acttcggata gacgtccggt aaccggttta ttggttaata cagggatgac gctgcgacgc
     2401 acagtatctt ctccgcgcaa gtcagcgtag gtattcaaca cctgctgacg tgccagaaat
     2461 gctgttatag tttctgcaac ggaatcacca ttcagcgcgg tttgtacgga aaaactgagt
     2521 atctgcaacg cccgtcgtcc ccggcgcgtt tcctgcaaaa tcacctcttc ccggcgctta
     2581 ttccaggcat cagtccgaat gtactgcgtg ataaaaaaca gccagcgaac tgaagcaacc
     2641 agtgaccaga taaaggcagg cacaccacag gccagccccc agaaatacgg gccgtttttt
     2701 gccagttcat cgctggcgaa taatgaagtc agggccacac cgacagacag catcagtaat
     2761 aaagctgtca gccacttaat tcgggctggc ggtacgggat agggttctgc gtcgggaatg
     2821 gtattaagtc ggactggcat cagtacatcc ctttattttg cattatcgac cagaagttaa
     2881 taaccaagtg aaatttaaag ttatgtatag agtcatttta tttatttaat gcaaaaatta
     2941 tgtaaccatc ttttgatggt agattatctg atgagtatgc tctttctcct gactttttcg
     3001 cattatcata gataatatat ttccctttcc atgtcccaac atccatttgg tttcggatga
     3061 taattaaaat attgtttttt ccaaaccata ccgcttcggg aatatttctc tctgcgaaac
     3121 aaaagccttc aggagagttc ttacctttaa acccattttc ccaaccagtt accagacaac
     3181 cttttatata tggagaacca tattccagcg caaagataag agaaccattt atgcactgag
     3241 aaagaaccac atctccaaaa aaatcataac ttttagttgg agtatctaaa aaggccccgg
     3301 tgataacatt tctgaatttt agatataatg tatcaccgtc aatggttcta agggaaagca
     3361 actgcacact ttcatttttt tcaattgaca ggttttcacg attttaatct tatcgcctga
     3421 aaaacagggg aaagaaaaaa aacaaagtaa tattaacata atgcgcatac tatcttccta
     3481 ttccctccat tagtatttgt atgttatcag gatctttagc cagtttttca gcgcaaggtt
     3541 ttataacaga atagtatgct tcatctgttc cacgatatgt ccgatatgcc tcctcaattg
     3601 ttgcttcttt atctatccag tattgcaaat actctgtgcc aatcttaata ttttcttttt
     3661 catcaaatat tttatcagat ttataaaatg tatcagcatt agcgaaagct tcatttgtct
     3721 ctttatcagt agtcattctt ccttttattt tttgttgtcg atatttaaaa acctgcctca
     3781 ctgcatttcg ttgcatttgc attaagcctt tcgcattatg tttattctta cctgcaaatt
     3841 gcttaaatct agattcttta tagatttgac aaataatata atcctctccc atgatggatt
     3901 tattattatt acggacaagt tgacgaattt gtttcaatct tatagctgga tctacattca
     3961 cttgttttgg tgcggtgtct tttgctggag ttaatttttc gctcttcttc gttagtgttt
     4021 tttttgctga tttatttgtg gtttcttttt tcttttcgga tttatctgcc atgttatatt
     4081 ctcgctatat gtcttaatta atttcatcgt ctaaaaactc atcgggttca aacacactaa
     4141 tattaacgac ctcctcctta tcagaggata ttagttctgt atttccattt tcatcagtaa
     4201 tcccactcat ttttagccca ctttccagtt ctagttcata gggccaatta ataagtggtt
     4261 gcccagtatt ttcatccagc aaaataaagc tctgattaaa atcctcagac ttaatcaccg
     4321 gaaatgccat cagctccggc gtcagcttcg ccttcggctt acgcccgtaa tatcccgcct
     4381 taacgttata ttctcccggc gtaccggcct ctatcccaca ggcatccagc cggatgtagc
     4441 tgccaccgcc gttaagggtg attttcttct tcgcggtgat tttaatctca tcttccgtac
     4501 tggtgatctc tatcgatttc tgcgccaaca gttccatcag atcgttctgt gcctgtaccg
     4561 agatcgcccc tttattggca aacagtttga tacccgcttt gcgtacaaac acgctcagcg
     4621 cctgacccac gccgataaac atattcttca cgacaccgat atcagcgtga tttcctgcgt
     4681 tcgcgatcag gtttttcgac gccgccagtt gcaggtgctc tccgctggcg atcgccacgc
     4741 ctttgggtgc gcttagcagg atcgcagcct gcgtcagatc ttttacactc tgctgcaaca
     4801 gcgctatctg tgatgacaga tctgccggat cggcattcgc cgtctgcgca tcagtggaca
     4861 gcgacttcat ctgtgactgt gcgccatcca gtattgccat cgccggagcc atttcgcgca
     4921 ccttaccctg cgccttgtcc tgcgcgtcgg agctgataaa gatgcctttc tttgcccgta
     4981 ctgtacccca cagatcggta cgcagttcaa agccttcccc gcgctgctgt tttccggcat
     5041 ccaccagatg gccgaggttg agctggctct tgccgccata ctcggtactg accttgatat
     5101 gctctttgcc gcgctcgtca tcgaggcgga ttttgttgtt cgccggggtg cgcagtacgt
     5161 tgcgcttgta gttctgaatg gtcacatggt cggtgtgtgc cgagtcgtgt tttacgcctg
     5221 caatataagg tcggtccggg ttgccttcct caaacgcgat gctgacttcc gttcccgcca
     5281 gcagcggcag atgcaggccg taggtgtctc ccgcatacgg gcgcgactgg cgtacccaca
     5341 ggctttcata acccggtttc cacgtatcgc ggtcaaagtc gaggttgacc cggtagcgcc
     5401 cgtccttgtc gatatgggcg tagatgtcgt tcttcaccgt gctggtgacc cgtgccggga
     5461 gcgtgccggc catcacgggg caggggataa gcgccgggcg gtagccatag cgttctgagt
     5521 acgggatggc ggtaaacgtc agttcatagc tgcggtcacg cgccgcgctg gccgtcacgc
     5581 cggtaatcag tacgcccttg cggaacaccg ctggcgcgtc gtcaccctga acttttatct
     5641 ccagccccgg catcagcagt gaactggtgc tctggccctg tagaatggcc tgttcattca
     5701 aatagcgttc gtggcggata cgggcataaa acgcgccgct ttccgctgcc tctttatcgc
     5761 ctttttgcag gaagttgtca gcgtagtggt aggcttcgcc gtaggtggtg ttatcgcccc
     5821 cggtggcgtc atgctggcct gtggtcattt ccgccgtggc ttcacggtag ttgtagtccc
     5881 gcgtggagac gcttttttcc accacgctgt acgcgctgtt caacccccat acggcttccg
     5941 tttcaccatc aaacagccct gaaggatgac gaagcggcag cgtcagtccg cgctcatagc
     6001 cgctctggtc gtcataaaac tcgacaactt cgattttcag ccgggcgtcg gtggcaaagc
     6061 ggaaccagat acccacctcc gacagcaggc gtgagacaaa cgtcaggtcg tcctcaccgt
     6121 actgcatcac ctgttcacgg gccgggtatt cgtttttgag gttaaacacg aagtcctgac
     6181 cgcgcatttg atggcgctcg cgcaggattt tttcgacgat ttgcggcacc gtctggttct
     6241 ggtagatggc gttctggcgg ctgcgggtaa gcagcgccat acggggttca aggcgcactt
     6301 cgtaacgggc ttcgtcctgt gacgatgaga ggtgtttaaa gctggtaatg acgccgtgca
     6361 gggtgcgcag ggcagtctgc accggcattc cctgcacggg cggtgccgtc aggctgaatg
     6421 cgccgtcctg catcagcacc gactccggcg ttattgcttt attggtactg gtaaactcaa
     6481 tgtcgtagcg gaagggtgag ctgagctgtt cgtggcccgt aaacgtcagc acatccgccg
     6541 ggcttttcag gccgcgaatt ttgagcttgt ggtgtgagtg gtcgaaattc agagtcggga
     6601 tatccatctc tgtactcctt tatatttatg aaaaataaat ccaagtatga ttctctttaa
     6661 aaagggaaaa atgcaaaaaa tataactaat taaagtaagc tacttataat ttctaatcat
     6721 ccctgcgagt atgtttcttt ccatcatctt tatttcctgg aggttcatcc gcatctggaa
     6781 tttcagatga gcgacgtaag aagaaatctt cagatataga aggtgtgtga tcaacctttt
     6841 gtatatcatg cacaaaaaag gaatatagtg tatttgccgt caaagatgat gatgatggca
     6901 gatttttatc attataaact gcgcgagaaa actcaaggaa tttcacagcc cgattgacag
     6961 cagcattata aacctgaggt ttaagtttta ttcggctatc atttttcctc gggttgacta
     7021 taaagtcatt tcgtaatcca atagctacac tttttacatc attcaaccat ccccatagtg
     7081 agtcaagttc tgaaatctgc gattttatat catcagcgtt agtatttgga ttaattcccg
     7141 tacctgcaag tggcccatag tcacttattt tcccacgatg agccgatgtc aactccttat
     7201 ccagacgttc ccgttcatac tgatacatat aatattgctc acccaaccag agaaaatagt
     7261 tatctagata cttctcctgc attgcctcac taaatacttt atccttcact tcctctcttt
     7321 gataacgact aacccagtaa tttacagatc ctccctgaac agcatcattc ataataaaat
     7381 agctggcaac tttcgtatca tattgatcca aagtgtcaaa atcaggaaat ggcacaccag
     7441 cttgacatgc tgcatgatac atattgtata gtgcaaccct gcacagttct gcactgggtt
     7501 tctgttcatc cggtttcaag ccaccaccaa tatcttcact acaaccggga agcagttctt
     7561 ccctgtattt tttattcgct gtatccgttt ttttccccaa cagatacaga ccacgccatg
     7621 gacgccgttc atgagctgct acaaggtgaa gtgcgttatt tactacgtcc ggcagtggtg
     7681 agtcctgatc aatagctttt tcacctaata ctgaaccaat cattttccct ggtaaaccca
     7741 accacataaa aaaatagtcc aacccattat tactactagt cggtgaatgc cgagaacagt
     7801 caaaaagacc aataaaagca atatctacca acgcgttttt atattggtgt tttttttctt
     7861 tatttttcag gcaaacttcc ttaagaaaat tatccaaaaa tttacgtgcc agtgtagctc
     7921 caaggtcaaa accgtataat gaaacagaaa tttttttgat gggaacatct cccttcatat
     7981 tttccgtata aaacttctta aacaatcgct ttgcagcttc aaggcgtacg ggttctcccg
     8041 tcataaaata ggcgctcatg gcttcgctat cacgcaacca aggtgtggac tcaattcctg
     8101 ctttgcctac cgacttagcc gccatcttgc caatcccttt aacccactct accggattat
     8161 tgagatcctc aaggagatta ccaagcacat ccgtccattt cttttctcct ttaataacag
     8221 actcccctgc atccgatata gtatcctctg gcagactttt catatcctcc agaaagttat
     8281 ctaaaccaat atccataaga gcgtgaatat tgtcgacaga atcgtcatgg taggcagtgc
     8341 ccattccgga gaaataaaat ttattataac aagtatcacc tgtatttttt tgttcatcag
     8401 gatatgcccg gaacaggcgg gcaatattac tcaaacggca gtctgtcgca tcccggtcga
     8461 tatttcgtcc cactccatca aaaaagaaag cgacatgcca gatccggcca caatttccca
     8521 ctttaccatc ttctgactgt tgtgctcgta cagctgcgga aatcactgat tcacttatca
     8581 cggctgcgcc tcctgatttt ttcgactcgg ataagaaggt tcttttcgtt tctcataggg
     8641 cgaaccagct ccttcactcc aacccaaaaa aaccttatca ccaggcaaga aatgtacatg
     8701 caaaaaatcc tgcccatgtt tcctttcagg caaaggcaga gtgatacgtc gaacttcttc
     8761 acgcagtccc gtattatact gagcgcgagt cgtactcaat gtccagacga cctcagcttc
     8821 tttccctctg atgtcaccgc agcaagtcgt tgaacctcca ccatgtgcaa acgcatttgc
     8881 cccagccatg ccgttcacgc tgaatcctaa tattggccta tccagttcac tatggatcac
     8941 caatatgact cctccagttg gagctcccca gattgatatt cctacacaca gtaaaaaata
     9001 agccacgggg atcgctatta gcatccgcca cacccaacgc ccccagcggg cataaccacg
     9061 cgtaagcttt tggtcaaatt tttccagtcg ggtaaatagc cccatcagat tttattccct
     9121 tttatcaatt ggttggcaaa gatgtatgtc actggcgacc aaggtcagac agcgatattt
     9181 catttcgttt caccttttcc agcatgacct gaaattcggc tgactcaaga tacgctttct
     9241 ttccattcag atagctcaac gcataaattt tctgatccag tggctttgtc aatccgacca
     9301 cctgagcctt attcaaggcc ttctccacca tatttcgctg aatacagggc gggaagtgct
     9361 cactcgtttt catggtgcgc cactctctta aaagcgcaga tacatctccc cgatccgcta
     9421 ttttctgcca gagcggttca tcaagcgtta tgatttccac tgtctcatcg ctgttatttg
     9481 ccacagtaag cggcatgttc agcctttgcc accgcgtatc ttccagcatc caccatgatt
     9541 ctatctgaga aaacattacc ggatgccagt ccatatcagg ccgggcagcc agttgtttca
     9601 gcactcgggg cgtgtagtac ctcagcagaa cttcacgacc atccggcgtt tttgccatac
     9661 atcccacagc aagccgagac gccagtggct ccagctgcaa ttcggagaaa gtaatgcctg
     9721 cgacaggtag tttcccgaca agcaccatcg ccagatcctt ttcactttca atacgaacca
     9781 accagggacc gtaagctgct acctttttaa gatcgggcag ttgatacagg gaaattcgtc
     9841 ggtatttata atgctccatc atgatctgaa gcatttcctg agagagcgct ccaccttcaa
     9901 ataaaataaa ggcgtttaac gtttcgtttc gcttaagcca gtggtctgcc agttgttgtt
     9961 ctgaagacat gattacactc cttcaacaac agcgtcatcg tttttgatgg cattcagcag
    10021 gcattcaaga caaaaatcgg atgagtccac ggctgaaagg atgggaaatt ctggcatagg
    10081 aaccttctcc gaggctttag gctgacgccc gtaatgtacc gctttgacgt tataatcccc
    10141 cggcgttccc ggctcaatgc cgctaccctc tatccggata taactcccac caccattaat
    10201 cgttattttt ttcttcgcgg tgattttaat ctcatcttcg gtactgacga tctctatcga
    10261 ttttttcgcc agtaactcca tcagatcgtg ctgcgcctgt accgatactg cgcctttatt
    10321 ggcaatcagc ctgatacccg ccttgcgtac aaacacgctc agcgcccgtc ccacgccgat
    10381 aaacatattc ttcactacgc cgatatcggc gttgtttccc gcatttatct ggaggttttt
    10441 caccgcggcc agttgcaggt gctcgccgct ggcgaccgcc acgcctttcg gtgcgtgcat
    10501 caaaatcacc gaggcggtca ggtcatttat ccggctggtt atcaatgcta tctgcgcggc
    10561 catatccgcc ggatcggcgt tcgccgtggc cgcatcgtca gacagtttct ggattttatc
    10621 gctcaggctg ttcagttcgc tgataatgtc ggccatttcg cgcacctgac cctgcgcctt
    10681 gtcctgcgcg tcggcgctga taaagatgcc tttctttgcc cgtactgcac cccacagatc
    10741 ggtacgcagt tcaaaacctt ccccgcgctg ctgtttcccg gcatccacca gatgaccgag
    10801 gttgagctgg ctcttgccgc cgtactcggt actgaccttg atatgctctt tgccgcgctc
    10861 atcgtcgagg cggattttgt tgttcgccgg ggtgcgtagc acgttgcgct tgtagttctg
    10921 aatggtcaca tggtc
//
LOCUS       DAPOXO010000130        10881 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPOXO010000130 DAPOXO010000000
VERSION     DAPOXO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10881
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.130"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            397..1464
                     /gene="pilL"
                     /locus_tag="ROH59_004579"
     CDS             397..1464
                     /gene="pilL"
                     /locus_tag="ROH59_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001360287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis lipoprotein PilL"
                     /protein_id="HDX4806976.1"
                     /translation="MKKNYLTLILPSLLSGCAGISGGNNVAPSDTPALVFVDGQISES
                     AGVLALTQQRLSPPKITPPPRVSVPETVKTAQPVSESRPLPSPTISQNFSRLIITGKP
                     GSTPVTLSPTARNRTVSQWIKTLLPEGWKFRQENAATPKLNTKLVSWSANDQWTRSLN
                     RLLEEQHLWGHLDWDNKTLTVTTSAAAPAQDTATTISPAAMVTTSTSPESSTTANSQN
                     KPRNPFRGNSVSPSTPAAIPTPTGSTVKSIPLMTGTPVKPVSQGKEWRAPAGTTLREN
                     IIKWAEETKCESMASTHWMVIWPLSVTDYRLDAPLMFRGSFESAMEQVFELYRTAQKP
                     LYAQASRMQCIITVSDTRDGR"
     gene            1464..1901
                     /gene="pilM"
                     /locus_tag="ROH59_004580"
     CDS             1464..1901
                     /gene="pilM"
                     /locus_tag="ROH59_004580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="HDX4806977.1"
                     /translation="MGWLVMAVGLTILIITGSYQNQKMSETTNAQQYASASVWASQIL
                     MIANRINDIRYVSGQQDGVISSDKLALPVTPDSRIKHQLQQGRLWVWMPEQPGLVETL
                     RLKSRGSALIGIFQNGQLTWLSGTATGLTPPAGITAGSVVYVN"
     gene            1915..3597
                     /locus_tag="ROH59_004581"
     CDS             1915..3597
                     /locus_tag="ROH59_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN family type IVB pilus formation outer
                     membrane protein"
                     /protein_id="HDX4806978.1"
                     /translation="MKKSHQRSMKLAVLPCMIAVALSISGCTFSEINKMQKKAQEDSA
                     HAREKVSALSARKSQALTWLDNQWINPVPVAQVSREKKQTAPACYITQARKGEITLQE
                     LGQRITAVCGIPVIITPDAANSTLEGGATRQMTGTLPAPDENGRLPLSSLGSTTMTTS
                     TQPLTLNNLMWQGDINGLLDLMASRSGLYWRMDNGRIVFYLTETRTYPLHMLNTKTSS
                     SSSVSSGSTSTMGATGGQDNSASGDATSSQSTTVGQEYDLYEDIRKTIEAMLTPEKGR
                     YWLSASSSTLTVTDTPAVQEAVARYVDEQNSIMNRQVALNVQVLSVSNTRNEQFGLDW
                     NLVYKSLHSAGATLNNASGDFTGATSAGVSILDTATGNAAKFSGSSLLIKALSEQGDV
                     SVVTSQESTVTNLTPVPIQMADQTVYVAQSATTTTTDVGATTTLTPGMITTGFNMTLL
                     PLIQKTGNLQLQMNFNLSDPPTIRSFTSKDGNSYIEMPYTKLRSLSQKVNLKEGQSLV
                     VTGFDQNNTTTSKAGTFTPANPLFGGSQTGKNERSTLVIIITPTFPSGGNNG"
     gene            3590..4885
                     /gene="pilO2"
                     /locus_tag="ROH59_004582"
     CDS             3590..4885
                     /gene="pilO2"
                     /locus_tag="ROH59_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001682966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4b pilus protein PilO2"
                     /protein_id="HDX4806979.1"
                     /translation="MADEDINPVVLLADPKVNHRVWAACLKWTPVVKKQRVPSHHKHK
                     YHVKPRRLTSLKVTVGSRNSRGKISRLTGTGILTRPERNHYFSLALAFCSWVRNGYGV
                     FRYSDKELLFLASINGQPAVMADLSGNDADVAQKVSLFLAMNEEPPEKWQVVSSLEHP
                     DNWESIITRLSSADLRHCKLTVGNRSKFTLPAVLFLVAAGAGTVFWMTQPEPDVGPTA
                     EEIAARARLQFKKPEPPPELPHPWASQPVISDFLKACADLRKPSPVALEGWKLTGGTC
                     TPETFTLIYERQPGGTIEGFLARSKEIFNVIPDFNLKDGARLASVTRLLPSLPRRDEA
                     VPAPSEQLMRVFTWFQKKQLTPAINEIAIPEPLPGNNGEPAPVQKWKEYQFSLSTPVN
                     PDELFPLFQDTGVRLSNIHFELNGGTFSYSSEGHIYASR"
     gene            4872..5324
                     /gene="pilP"
                     /locus_tag="ROH59_004583"
     CDS             4872..5324
                     /gene="pilP"
                     /locus_tag="ROH59_004583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilP"
                     /protein_id="HDX4806980.1"
                     /translation="MRPGKSLIIPSIFFFSGFSFATTQPLVTIGELEAQQNRNILLQA
                     KVQGAQLQKQLEESDVNLSSETVSGFSGMTASLPSVSEQPTSKNRKELPVIMEINGKD
                     KRLHAVLRMADGRQTSVTTGSQLPGTSVTVKSISLSGVTLSDGTTLTF"
     gene            5335..6888
                     /gene="tadA"
                     /locus_tag="ROH59_004584"
     CDS             5335..6888
                     /gene="tadA"
                     /locus_tag="ROH59_004584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDX4806981.1"
                     /translation="MDKYNLKDALLFISRGDTHEILIETNQRTRPDVQSNLQELLNLY
                     PDIIPKVVSLSELQEAGQDDENKGPKERIIHLKDLADVSESEKKVLSYFETARKLGAS
                     DIHFLISESIFKVRMRIFGELQTVDEDQPALGYSLCATAILSMADVTETSFFPQREQD
                     ARLSPQLMRKIGIFGARYSHRPTGDGLIAVMRLIPDDGDKVPTFKQLGFIPEQIRLLN
                     VMLRRPEGKIVLSGPTGSGKSTTLRSACRVYLDDNQGRHLLTIEDPLEGQILGATQTP
                     IICDKSDEEAVKLAWSRAISSAMRLDPDAIMEGEMRDLVSMMSTTYAAQTGHIVLTTL
                     HTNSALGIPERMITMGMNADLICDAQLLIGMISQRLVPTLCPSCRIPWEKRVPELSED
                     DRAYLERHCNKDSLCSTDNIWFRNPHGCSDCNHDVIINGRKRGEIGKGLTGRTVIAEV
                     IEPDNRLFQILKTRGKVAARKYWLENMHGISRVEHLLRRINDGLVDPLEADRIIPLDE
                     DERLSIDDA"
     gene            6901..7986
                     /locus_tag="ROH59_004585"
     CDS             6901..7986
                     /locus_tag="ROH59_004585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDX4806982.1"
                     /translation="MREMNFSQRLRRFIVRKTFSAPYRVQFYEALRFLLENKQPLKTA
                     LEQMRDAWTDFGRKWHPFAELATDCIESLRENSGENSLEYTLGLWVPQEEAAVISAGI
                     RSGSIVDALQFATTLTDAKKQLHQAIWQMAIYPVGLLIMMTGTLYVLNTELIPVLSKI
                     SSPDSWSGALGFLYGLSLFVDNYGAICAVLFAVVTGVISWSLKNWKSRSLADNIMPWS
                     IYKDIQGAAFLLNMAALLKAKMTTLNSLNVLQDFASPWLSTRLDSIIYRVRQGDHLGL
                     ALRQCGYQFPSREAANFLSLLQGDGATELIGNYGQRWLVQTLERVKKRAAVVRLIMLI
                     FLVMSLLLLVMAVVDIQSIGDNSMGNL"
     gene            8003..8617
                     /locus_tag="ROH59_004586"
     CDS             8003..8617
                     /locus_tag="ROH59_004586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilX"
                     /protein_id="HDX4806983.1"
                     /translation="MLIQNIDVNALKKNEKETSHDKGWGIMEQGAIALVVIIVLALVF
                     GGLYMLRSRTGVANESSNIQTIITSTQGLLKGSDGYTFTSGTKMTGALIQMGGVPKTM
                     TVRGTPSSGTATLYNSWGGAVTVAPASTSGFNNGFTVTYEKVPQDACIQIATQISRTG
                     LTNGITLNSTTHNDGKVTTEEASAQCTADNGSTGTNKLIFTING"
     gene            8627..9187
                     /locus_tag="ROH59_004587"
     CDS             8627..9187
                     /locus_tag="ROH59_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDX4806984.1"
                     /translation="MSGGKVPLRLISLILLCSLIYPARASYIAPKQIWTNKWDNCFAA
                     AGARYQIEPLLLKAISAGESSLKPGAININKDRKTGKASSTDYGLMQINSTHIPKLIK
                     MGVIKKSEDLITKPCLNIHIGSWILARHFQICGVSWNCLGSYNAGFRKDRHETREQYA
                     NKVWRIYRDMKGICLPGQGGRQCRQS"
     gene            9172..9828
                     /locus_tag="ROH59_004588"
     CDS             9172..9828
                     /locus_tag="ROH59_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDX4806985.1"
                     /translation="MQTIVGISLSPVYILPLMFIFSIIGRTLLFRVRYFLSDTEHLWY
                     KTHTAVLSGIWLYSIAVALIILSSSPLLYRIHAVLILSFMLQMAVTDALTGLLPGTFT
                     RRFLIAGILSQITTDIWWLRATEIVSAAIVLFCLHKLVNRHRLNIGTGDLWLIAGITA
                     WSGLYNAIWSVLLGAGGFVLWHSTWCIKGHKEGPLGPWLCLGHVLLLLDNLYQPLWVI
                     "
     gene            9816..>10881
                     /gene="pilV"
                     /locus_tag="ROH59_004589"
     CDS             9816..>10881
                     /gene="pilV"
                     /locus_tag="ROH59_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="HDX4806986.1"
                     /translation="MGNLMKKYDRGWASLEIGAALLIVMIIVAWGAGIWQDYLKTKGW
                     QAEARLVSNWASAARSYIGKNYTTLQASSTTTTPAVITTTMLKNTGFLSSGFTETNSE
                     GQRLQAYVVRNTQNPELLQAMVVSSGGTPYPVKALIQMAKDITTGLGGYIQDGKTATG
                     ALRSWSVALSNYGAKSGNGHIAVLLSTDELSGAAEDTDRLYRFQVNGRPDLNKMHTAI
                     DMGSNNLNNVGAVNAQTGNFSGNVNGVNGTFSGQVKGNSGNFDVNVTAGGDIRSNNGW
                     LITRNSKGWLNETHGGGFYMSDGSWVRSVNNKGIYTGGQVKGGTVRADGRLYTGEYLQ
                     LERTAVAGASCSPNGLVGRDN"
BASE COUNT         3147 a         2593 c         2475 g         2666 t
ORIGIN      
        1 tcccgcattt gcattcggac ggaatgacag tcgtcattcg tcctctccag acccaccaca
       61 ccaattaaaa aatacattta gatataaaaa gaatgctcat aagcaggatt tttattttca
      121 caaaaaatcc caaaacactg gcttaattgg ctatccacaa cctcaccttt aaaataacat
      181 gcaacattaa aattcaaaaa atagaataat gaaaatacta atcaacaata ttaaagaccc
      241 aagcagactt ctgaatgcga ctaaaacggg acattcagga gtaattctct caataccggt
      301 atacattacc catccaattg cacataaaat aatgaaccct tacttaaagt ccgcattaac
      361 taacaaacac gtatatacga acacggagtc tccgttatga aaaaaaacta tctgacactt
      421 atactgccgt cattattgtc cggctgtgcc ggaatttccg gcggcaataa cgtggcacca
      481 tcagatacgc ctgctctggt ttttgttgac ggacaaatca gtgagagtgc tggcgtcctg
      541 gcacttacgc aacaacgact ttctccacct aaaataactc cgcccccgag agtcagcgtg
      601 ccagagacag taaaaacagc acagccagta agcgaatccc gaccgttacc ttcaccaaca
      661 ataagtcaga atttctcccg gttaatcatt acaggcaagc ctggtagcac ccctgtaaca
      721 ctatcgccga cggcccgtaa ccggaccgtc agtcagtgga taaaaacatt actaccggaa
      781 ggatggaaat tcagacaaga gaatgcagcc acgcccaaac tgaataccaa actggtttca
      841 tggtctgcca atgatcagtg gacccgttct ctgaaccggt tgctggaaga acaacacctc
      901 tggggccatc tggactggga taataaaacg ttgaccgtca caacatcggc tgctgcaccg
      961 gcacaggaca cggcaaccac tatctcgcca gcagccatgg taaccacatc cacttccccg
     1021 gagtcttcaa cgacagcaaa tagccagaac aaaccacgaa acccattcag gggaaacagc
     1081 gtatctccgt ctacgcccgc agcaatcccg actccgaccg gctctacagt caagtctatc
     1141 ccactcatga ccgggacacc tgtcaaaccg gtatctcagg gtaaagagtg gcgtgcgccg
     1201 gcaggcacta cattaaggga aaacattatt aagtgggcag aagaaacaaa atgcgaaagc
     1261 atggcatcaa cgcactggat ggtcatatgg ccactttctg taaccgatta ccgtcttgat
     1321 gcgcctttga tgttccgggg atcatttgaa tcagccatgg agcaggtatt tgagttatat
     1381 cggactgcgc aaaaaccttt atacgcacag gcttctcgca tgcagtgcat cattacagtt
     1441 tctgatacaa gggatggtcg ctaatgggat ggctggtcat ggccgtcggc ctgaccattc
     1501 tgattatcac tggtagctac cagaatcaga agatgtctga aaccacaaac gcccagcaat
     1561 atgcaagtgc gtctgtatgg gcaagtcaga tactaatgat tgctaacaga atcaatgata
     1621 tcagatacgt atcaggccag caggacggag taatttcctc agataaactg gctctccctg
     1681 tcactccgga ctcccgaatt aaacatcagt tacaacaggg gcgtctgtgg gtatggatgc
     1741 ctgaacaacc aggacttgtt gaaactttgc gtttaaaaag tcgtggttct gcactaatag
     1801 ggatcttcca aaacgggcaa ctcacctggc tatcaggaac tgcaaccggt ctgacacccc
     1861 cggcaggcat tactgctggt tctgtcgtct acgttaacta atctggatat attcatgaaa
     1921 aaatcacacc agcgttcaat gaagctggcg gtgctcccct gcatgatcgc cgtcgctctt
     1981 tccatctccg gatgtacttt cagcgaaatc aacaaaatgc agaaaaaagc acaggaagac
     2041 tcagcacatg cacgggaaaa ggtatcagcc ctttcggccc gtaaatcgca ggctcttacc
     2101 tggctcgata atcaatggat aaaccctgtt ccggtcgctc aggtatcaag agagaaaaaa
     2161 caaacagctc cagcctgcta catcacgcag gcaagaaaag gagagatcac tctgcaggaa
     2221 ctggggcaac gtattactgc cgtatgcggc atccctgtga tcatcacgcc tgacgcagcc
     2281 aattcaactc ttgaaggagg cgctacccgc cagatgacag gaacactacc agcaccagat
     2341 gaaaatggac gtctaccgtt aagcagcctg ggcagcacaa caatgactac ctccactcag
     2401 ccattaacgc tgaataacct catgtggcag ggagatatca atggtcttct ggatctgatg
     2461 gccagccgga gtggtctgta ctggcgcatg gataatggtc ggattgtatt ctatctgact
     2521 gaaaccagaa cgtatccact tcatatgctg aacaccaaaa ccagcagcag ttccagtgtc
     2581 agctctggct caacaagcac aatgggggca acaggaggcc aggataactc agcatccggt
     2641 gatgcaacgt cctctcagag cacaaccgtt ggtcaggaat acgatctgta tgaagatatc
     2701 cggaaaacta ttgaagcaat gctgacacca gaaaaaggcc gttactggtt atctgcatcg
     2761 agctcaacgc tgacagtcac tgatactcca gctgtccagg aagccgtcgc acgatatgta
     2821 gacgaacaaa acagtattat gaaccgccag gtagccctga acgtacaggt tctgagcgtc
     2881 agcaatacca gaaacgaaca gttcggtctg gactggaacc ttgtttataa atcgctacat
     2941 tccgccggag caacgttgaa caatgcaagc ggagatttta caggcgctac atctgcaggc
     3001 gtatcaattc tggatacggc aacagggaat gccgccaaat tcagcggttc cagccttctg
     3061 attaaagcac tgagtgaaca aggcgatgtc agcgttgtaa cttcacaaga aagcactgtc
     3121 acaaacctga cgccggtacc tatccagatg gcagatcaga cagtttacgt cgcccagtca
     3181 gcaacaacta cgactacgga tgtaggagca acaacaacat taacaccggg catgatcacc
     3241 actggattca atatgaccct gctgccttta attcagaaaa caggcaatct ccagttgcag
     3301 atgaacttta atctgtctga tcccccaact atccgtagct ttacgtcaaa agacggaaac
     3361 agttacatcg aaatgccata taccaaactg cgttcactga gccagaaggt caatctgaaa
     3421 gaagggcaat cacttgtcgt tactggtttc gatcagaaca atacgacgac aagtaaagcc
     3481 ggtacattta cgccagcaaa tccattattt ggtggttcac aaaccgggaa aaatgaacgc
     3541 agcacgcttg tgatcatcat taccccgact ttcccgtcag gaggcaataa tggctgatga
     3601 agatatcaac ccggtagtgc ttctcgcaga tcctaaagta aatcatcgcg tgtgggctgc
     3661 ctgtcttaaa tggactcctg tcgtaaaaaa acagcgcgtc ccctcacatc ataaacacaa
     3721 gtatcatgta aaacccagac ggcttacctc cctgaaagtg actgtaggca gcagaaattc
     3781 ccgtggaaag atcagccgcc ttaccggcac aggaatactg accaggccag aacgcaatca
     3841 ttatttttcc ctggcactgg ctttctgctc atgggtcaga aatggatacg gtgtcttccg
     3901 gtacagcgat aaggagctct tattccttgc ttccattaat ggccagcctg ccgttatggc
     3961 tgacttatca ggaaatgatg ccgatgttgc ccaaaaggtc agcctttttc tggcgatgaa
     4021 cgaagagccc cccgaaaaat ggcaggttgt atcgtctctg gaacatcctg ataactggga
     4081 aagtattatt acccggttat catcagcaga cctccgccat tgcaaactta ctgtcggcaa
     4141 tcgcagcaaa ttcacactgc ctgccgtact gtttttagta gcagccggcg caggcacagt
     4201 attctggatg actcagccag agcctgatgt cggaccgacc gccgaggaga tagctgcacg
     4261 ggcaagatta cagtttaaaa agcccgaacc accaccggag ctcccgcatc catgggcgtc
     4321 acaacctgta atcagtgatt ttctgaaagc ctgcgcggac cttcgaaaac catcaccggt
     4381 cgcgctagaa ggctggaaac ttaccggtgg aacatgtact cccgagacat tcacactgat
     4441 ttacgaacga cagccaggag gaactattga aggctttctg gcaagaagca aagaaatctt
     4501 taatgttatt cctgacttta accttaaaga tggtgcacgc ctggcttctg taacccggct
     4561 actgccttcc ctgcctcgca gggatgaggc agtccctgcc ccctcagaac aactgatgcg
     4621 ggtgttcacg tggtttcaga aaaaacagtt aacgccggcc attaatgaaa tagccatacc
     4681 ggaaccatta ccaggtaaca atggtgaacc agcccctgtt cagaaatgga aagaatatca
     4741 gttcagttta tcaacgcctg taaatcctga tgagttgttc cctttatttc aggataccgg
     4801 cgttcgtctg agcaatatcc attttgaatt aaacggcggt actttcagtt attcctcaga
     4861 aggtcatatt tatgcgtcca ggtaaatcac tcattattcc atccatattt ttcttctccg
     4921 gtttttcatt tgcaacaaca caacctcttg tcacaatagg agaacttgaa gcacaacaaa
     4981 accggaatat tcttttacag gcaaaagttc agggcgcaca gctacagaaa caactcgaag
     5041 aatcagatgt taatctgtca tctgaaactg tttcaggttt ctctggtatg actgcctctt
     5101 tgccatcagt ttcagagcag ccgacatcta aaaacagaaa ggaattgccc gttattatgg
     5161 aaataaacgg caaagataaa cgtcttcatg ccgttcttcg catggctgat ggacgtcaga
     5221 caagcgtcac cactggtagc cagcttccgg gtacatccgt cacggtgaag tcgatctcat
     5281 tgtctggcgt cacgttaagt gatggcacca cccttacttt ctgagtgatg tgatatggac
     5341 aaatataatt tgaaggatgc tctccttttt atatcccggg gagacaccca tgaaattctc
     5401 atcgaaacaa atcagcgaac aagacctgac gtacagagta atctccagga actgctaaac
     5461 ttataccctg acatcatccc aaaagtagtc tcgctgtctg agttacagga agccggtcag
     5521 gatgatgaaa ataaaggtcc gaaagaacgg attattcatc tgaaagatct tgcagatgtc
     5581 agtgaaagtg agaagaaagt tctctcctat tttgaaacgg ccagaaaact tggtgcttca
     5641 gatattcatt ttttaatttc agagtctatt ttcaaagttc gcatgagaat attcggtgaa
     5701 ctgcaaactg tagatgaaga tcaacctgcg ttgggttatt cactttgcgc aacagccatt
     5761 ctgtcaatgg ctgatgtgac tgaaaccagt ttcttccctc aaagggaaca ggatgcgcgc
     5821 ctgtccccac aattaatgcg aaaaatagga atatttggtg cacgatacag tcacagacct
     5881 acgggagatg gtctgattgc agttatgcgc ctgatacccg atgacggaga caaagttccc
     5941 acgtttaagc aactgggctt tataccggag caaatccggt tgctgaacgt catgctgcgc
     6001 cgcccggaag ggaaaatagt tctgtctggt ccaacaggtt caggtaaatc aacaacgtta
     6061 cgcagtgcct gccgtgtata tcttgacgat aatcaggggc gacacctgct gacgatcgaa
     6121 gatccgctgg aaggacagat tctgggggca acacaaaccc cgattatctg tgacaaatcc
     6181 gacgaagagg ccgtcaaact ggcatggagt cgtgctattt catcggcaat gcgacttgac
     6241 cccgatgcca tcatggaagg ggaaatgcgc gatcttgtct cgatgatgtc aacaacctac
     6301 gcggctcaga ccggtcacat cgttctgacg acattacata caaactcagc tctgggtata
     6361 ccggagcgga tgattacgat gggtatgaat gccgatctta tttgcgatgc gcaattactg
     6421 attgggatga tcagccagcg tcttgtacca actctgtgtc cctcctgccg tattccatgg
     6481 gaaaagcgag tacctgaact tagcgaagac gaccgcgctt accttgagcg gcactgcaat
     6541 aaagattcac tctgcagtac agataatatc tggttccgaa atcctcacgg atgctccgac
     6601 tgtaatcacg acgtaattat taacggcaga aagcgcggtg aaataggtaa aggcctcacc
     6661 ggcaggaccg taattgctga agtgatagaa cctgataatc gcttatttca gattctgaaa
     6721 acacgcggca aagttgcagc acgtaaatac tggcttgaaa acatgcatgg catcagtcgt
     6781 gtagagcatc ttcttcgccg tatcaatgac ggcctggtgg accctcttga agccgacaga
     6841 atcatccctc tggacgaaga cgaacgcctc agcatcgatg atgcctaaca ggagaacaac
     6901 atgcgtgaaa tgaatttcag tcaacggctg agacgtttca ttgtcagaaa aacgttcagc
     6961 gccccctaca gggtgcagtt ttacgaagct ctgcgttttc tgctggaaaa taaacagcca
     7021 ttaaagaccg cactggaaca gatgcgggat gcctggacag actttggacg aaaatggcat
     7081 ccctttgctg aactggccac agactgtatt gagtctcttc gtgaaaacag tggcgaaaac
     7141 tctctggaat atactcttgg tttatgggtt ccccaggaag aggctgcagt aatcagtgcc
     7201 ggaataagaa gtggttccat tgtggatgca ttacaatttg ccaccacact tacagatgcc
     7261 aaaaagcaac tccatcaggc catatggcaa atggctattt acccggtggg gttgttaatc
     7321 atgatgacgg ggacattata tgttcttaat acagagctaa tacctgtact gagcaaaata
     7381 agctcccctg attcatggag tggtgctctt ggttttctct atggattatc tttgtttgtc
     7441 gataattacg gcgctatatg tgccgttctt tttgcagtgg tcacaggtgt aatatcatgg
     7501 tctctgaaaa actggaaaag ccgctctttg gctgacaata taatgccatg gagtatttat
     7561 aaggatatac agggggcagc attcctcctg aatatggctg cacttctgaa agccaaaatg
     7621 acaacgctca actcactgaa cgttcttcag gactttgcat caccatggtt aagcacacgc
     7681 cttgacagca ttatttaccg cgtacgccag ggggatcacc ttgggctggc tttgcgtcag
     7741 tgcggttatc agttcccatc cagggaagca gccaacttcc tgtctttatt acagggagat
     7801 ggcgcaacgg agctaatcgg caattatggc caacggtggc ttgtacaaac gctggagcga
     7861 gtaaaaaaac gagcagctgt tgtgcgttta attatgctga tatttcttgt catgtcactc
     7921 ctgttactgg tcatggccgt tgtagacatt cagtctattg gcgacaacag tatgggtaat
     7981 ctttaaataa aacgaggtat ttatgttaat ccaaaatatt gatgttaacg ctctgaagaa
     8041 aaatgagaaa gaaacgtctc atgacaaagg ctggggtatt atggaacagg gtgcaatagc
     8101 acttgttgta attatcgtac ttgcccttgt ttttggtgga ttgtatatgt tgcgttcacg
     8161 aaccggtgtg gcaaatgaaa gttcgaacat acagacaatc atcacaagta ctcaggggct
     8221 gctaaaaggt agcgatggat atacgtttac cagtggaacc aaaatgacgg gtgctctcat
     8281 tcagatgggt ggcgtaccca agactatgac agtgcgtggt actccatcat caggtacagc
     8341 aacgctctat aactcatggg gcggtgccgt aactgttgct ccggcttcaa catcaggttt
     8401 caacaatggt tttaccgtca cctatgaaaa agtcccacag gatgcctgta tccagattgc
     8461 cacacaaatc agtcgtactg gtttaactaa cggtattacc ctgaacagta cgactcacaa
     8521 tgatggaaaa gtcactactg aagaagccag tgcgcaatgc acagctgata atggcagcac
     8581 cggtacaaac aaactaatct tcaccatcaa tggctaagga gttttaatgt ccgggggtaa
     8641 agtgcccctc agacttattt cattaatcct gctttgttct cttatttatc ccgcccgagc
     8701 ttcatacatc gcccccaaac aaatctggac taacaagtgg gacaattgct ttgccgccgc
     8761 cggcgcacgc tatcaaattg aaccattatt gttgaaggcc atttctgccg gggaatcttc
     8821 attgaagccg ggcgcaatta acataaataa ggacagaaaa acaggcaaag ccagtagtac
     8881 ggattatggg ttgatgcaaa taaactcaac ccatattcca aagcttataa agatgggcgt
     8941 aatcaaaaag tctgaggatt taattaccaa accatgtctt aatatccata taggaagctg
     9001 gatactggca agacattttc agatatgtgg cgtcagctgg aattgccttg ggtcatacaa
     9061 tgccggattc cgtaaggaca gacatgaaac aagagagcaa tatgctaata aagtatggag
     9121 aatttatcgt gacatgaaag ggatatgcct tcccgggcag ggaggcagac aatgcagaca
     9181 atcgtaggca taagtctctc ccctgtttat atcctcccat tgatgttcat attttccatt
     9241 attggacgga ctctgttatt cagagttcgt tattttttat ctgatacaga acatctctgg
     9301 tataagacac acactgcagt tctgtcagga atatggctat atagtatagc tgtggcatta
     9361 attattttat cgtcatcccc acttctctac cgtattcatg ctgttcttat tctttcgttc
     9421 atgctgcaaa tggcagtaac ggatgcacta acaggcctct taccgggtac attcaccagg
     9481 cgttttttaa tcgctgggat attatcacaa atcacaactg atatatggtg gctccgtgca
     9541 acagaaattg tctctgccgc aattgtctta ttctgtctgc ataaactggt taaccgccat
     9601 cgtcttaata ttggcacagg agacctgtgg cttattgcag gtattaccgc atggtcaggg
     9661 ctatataacg ccatatggag tgtgttgctg ggcgcaggag gatttgtctt atggcattca
     9721 acatggtgca taaaaggaca taaagaaggc ccactgggtc catggctgtg tcttggccat
     9781 gtccttttgc tactggataa tctttatcaa ccactatggg taatctgatg aaaaaatatg
     9841 accgaggctg ggcatcgctg gaaattggcg cggctttatt gattgttatg atcatagttg
     9901 cctggggtgc aggcatatgg caggactatt taaaaaccaa aggttggcag gctgaagctc
     9961 gtcttgtcag caactgggcc agtgcagccc gctcttatat agggaaaaac tacacaactc
    10021 tccaggccag tagtaccaca acaacccctg ccgttatcac gacaaccatg ctgaaaaata
    10081 ccggcttttt gtccagcggc tttactgaga caaacagcga ggggcagcgg ttacaggcat
    10141 atgtagttcg aaacacccaa aacccggaat tactacaggc aatggtcgta tccagtggtg
    10201 gcacacctta tccagtgaaa gcacttatac agatggctaa ggatattacc actggtcttg
    10261 gtggatacat ccaggacggc aaaacagcca caggtgcatt acgttcctgg tcagtagctt
    10321 taagtaatta tggtgccaaa agtggtaatg gacatattgc cgtattgtta tcgacagatg
    10381 aacttagtgg cgcagctgaa gacaccgatc gtctttacag attccaggtc aatggtcgcc
    10441 ctgacttaaa caaaatgcac acggccattg atatgggatc aaataacctg aataacgttg
    10501 gggcagtaaa tgcccagact ggtaatttca gcggcaatgt gaatggtgta aatggcactt
    10561 tcagcggtca ggtaaaaggc aatagcggaa actttgacgt aaatgtcacc gctggcggtg
    10621 atatcagaag taataatggt tggttaatta ctcgtaacag caaaggctgg ctcaatgaaa
    10681 ctcacggtgg cggattttat atgtccgatg gatcatgggt tcgaagtgta aacaacaagg
    10741 gcatctatac cggcggtcaa gtgaaaggcg gtactgttcg ggctgatggt cgcctttata
    10801 ctggtgaata cttacaactg gaaagaactg ccgttgctgg cgcatcatgt tcgcctaacg
    10861 gccttgtagg ccgcgataat a
//
LOCUS       DAPOXO010000131        10795 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.131, whole genome shotgun sequence.
ACCESSION   DAPOXO010000131 DAPOXO010000000
VERSION     DAPOXO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10795
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.131"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            6..992
                     /locus_tag="ROH59_004590"
     CDS             6..992
                     /locus_tag="ROH59_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806987.1"
                     /translation="MYHHDFNEKIGFWYVIALAGQSNGMAYGEGIPLPDTLDKPESRV
                     KQLARRKTITPGGKECKFNEIIPADHCLHDVQDMSGYHHPAADLHKGEYGCVGQGLHI
                     AKKLLPYIPEQAGILLVPCCRGGAAFTVGAEGMYVPDTGATADAMRWGTGTALYEDLV
                     ARVKVALEYNRKNKLLSVCWMQGEFDLMSPDYEKHPDLFYQMVTSFRSELSEYSSQCV
                     GNSSERVPWLCGDTTWYWKESYQKEYDFIYGHYRQRTDDEIHFLSFQDSNRHELTNEP
                     EEDADDLSVGYLGSSWRTELSWTTSQRSTHFNSMARRGVIAECYAQKIRNYL"
     gene            1144..2372
                     /locus_tag="ROH59_004591"
     CDS             join(1144..1459,1459..2372)
                     /locus_tag="ROH59_004591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX4806988.1"
                     /translation="MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAAS
                     QLFLWRKQYQEGSLTAVAAGEQVIPASELAAAMKQIKELQRLLGKKTMENELLKEAVE
                     YGRGKKVDSARALIARGWGVSFVSRCLRVSRAQLHVILRRADDWKDGRRSRHTDDTDV
                     LRRIHHVIGELPTYGYRRVWALLRRQTELDGMPAINAKRVYRTMRQNALLLERKPAVP
                     PSKRAHTGRVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHWAVTTGGFD
                     SETVQDVMLGAVERRFGSELPASPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRS
                     PESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREY
                     LRQWASDGLSDNRCLEI"
     gene            2872..4962
                     /gene="iha"
                     /locus_tag="ROH59_004592"
     CDS             2872..4962
                     /gene="iha"
                     /locus_tag="ROH59_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional siderophore receptor/adhesin Iha"
                     /protein_id="HDX4806989.1"
                     /translation="MRITTLASVVIPCLGFSASSIAAAEDVMIVSASGYEKKLTNAAA
                     SVSVISQEELQSSQYHDLAEALRSVEGVDVESGTGKTGGLEISIRGMPASYTLILIDG
                     VRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
                     ADKWLSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSVSLQVRGSTQQRQGSSVTSL
                     SDTAATRIPYPTESQNYNLGARLDWKASAQDVLWFDMDTTRQRYDNRDGQLGSLTGGY
                     DRTLRYERNKISAGYDHTFTFGTWKSYLNWNETENKGRELVRSVLKRDKWGLAGQPRE
                     LKESNLILNSLLLTPLGESHLVTVGGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDE
                     WHLTDALALTVGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLH
                     KGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAGLNANVTGFMTDFSNKIVSY
                     SINDNTNSYVNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNKGAPLSY
                     TPEHMVNAKLNWQITEEVASWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAW
                     TVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYV
                     IPERNYWMSLNYQF"
     gene            complement(5180..5339)
                     /locus_tag="ROH59_004593"
                     /pseudo
     CDS             complement(5180..5339)
                     /locus_tag="ROH59_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066419.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            5824..6066
                     /locus_tag="ROH59_004594"
     CDS             5824..6066
                     /locus_tag="ROH59_004594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806990.1"
                     /translation="MKDEIHSTSINPDVVEQFLALMNTHCKSSEEALAMLSTLCYNLM
                     VTCGIHSMDSQMLNGHGISMQLQGIDIAERPGKNIH"
     gene            6357..6716
                     /locus_tag="ROH59_004595"
     CDS             6357..6716
                     /locus_tag="ROH59_004595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806991.1"
                     /translation="MKDNSTTATPEAWKMRFLANGTSGTWFYTDDITVTDAWLRAHPD
                     DVEVIPLCRIPPRQHSHEQHIEELRAALARMLHMHHMMLETTHYRENITDARCIREMH
                     EAPLQALNILARYPHEV"
     gene            6720..6935
                     /locus_tag="ROH59_004596"
     CDS             6720..6935
                     /locus_tag="ROH59_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806992.1"
                     /translation="MWLLIFWLSSPFNVSSGDARQPTLAVHSQAFHTERACRDALHAI
                     KKENVGEFSLRGVCVSDGNTKEEAESS"
     gene            complement(7513..7835)
                     /locus_tag="ROH59_004597"
                     /pseudo
     CDS             complement(7513..7835)
                     /locus_tag="ROH59_004597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000555401.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7855..8364
                     /locus_tag="ROH59_004598"
                     /pseudo
     CDS             7855..8364
                     /locus_tag="ROH59_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
     gene            complement(8398..9930)
                     /locus_tag="ROH59_004599"
                     /pseudo
     CDS             complement(8398..9930)
                     /locus_tag="ROH59_004599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013317439.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(10346..>10795)
                     /locus_tag="ROH59_004600"
     CDS             complement(10346..>10795)
                     /locus_tag="ROH59_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806993.1"
                     /translation="VSAIASTPQTEFSWFRYGQYNETGIYISIEKTIIITITVSGGCF
                     KKEYSIVSHMLVTDTITEATLYENGLYTRHIRLSRPVSDSKYPLPPGSQLIKNMTLRL
                     RLQDQQEETSVTLFQGKISTDGNNYSIIKGKVSSVLLLLKMLQINHA"
BASE COUNT         2800 a         2495 c         2728 g         2772 t
ORIGIN      
        1 gaatgatgta tcatcatgat tttaatgaaa aaataggttt ctggtatgtg atagccctcg
       61 caggacagtc taatggtatg gcctacggtg aaggtattcc cctgccagat acactcgaca
      121 aacccgagtc ccgtgtaaaa caactggctc gtcgaaaaac aatcacacca ggaggaaaag
      181 agtgtaaatt caatgagatt attccggcag atcactgcct gcatgatgtt caggatatga
      241 gtggatatca ccatccggct gctgatttgc ataaagggga atatggttgt gtcggacagg
      301 gattgcatat agctaaaaag ttactgccat acatacctga gcaagcaggg atattactgg
      361 ttccttgttg cagaggaggt gccgccttta ctgttggagc tgaaggtatg tatgtacctg
      421 atacaggggc aacagctgat gcaatgcggt ggggcaccgg aacagcactc tatgaggact
      481 tagtagcccg ggttaaggta gctctggaat ataacagaaa gaataaactg ctatctgtct
      541 gctggatgca gggggagttt gatcttatgt caccagatta tgaaaagcat cctgacttgt
      601 tttatcagat ggtaacttct ttcaggtctg agttatctga atactcatct cagtgtgttg
      661 gtaattcgtc agaaagagtt ccatggttgt gtggtgatac aacctggtac tggaaggaat
      721 cttatcaaaa agaatatgat tttatatatg gacattacag acaacggact gatgatgaaa
      781 tacattttct cagctttcag gatagtaacc gacatgaatt aactaatgag ccagaagaag
      841 atgccgatga tttatctgtc gggtatctgg ggtcatcatg gaggacagaa ttaagctgga
      901 caacgtcaca gagaagtaca cattttaatt caatggccag aaggggagtt attgctgaat
      961 gttatgcgca aaaaataaga aattatttgt agacaagttc aggatatatc tacagctctg
     1021 acatgattct ctgagagaca tgacggagtg gttagactgg ccccctgaat ctccagacaa
     1081 ccaatatcac ttaaataagt gatagtctta atactagttt ttagactagt cattggagaa
     1141 cagatgattg atgtcttagg gccggagaaa cgcagacggc gtactacaca ggaaaagatc
     1201 gctatcgttc agcagagctt tgaaccggga atgacggtct cccttgttgc ccggcaacat
     1261 ggtgtggcag ccagccagct atttctctgg cgtaagcaat accaggaggg aagtcttact
     1321 gctgtggctg ccggagaaca ggtcattcct gcctctgaac ttgctgccgc catgaagcag
     1381 attaaagaac tccagcgtct gctcggcaaa aaaacgatgg aaaatgaact ccttaaagaa
     1441 gccgttgaat atgggcgagc aaaaaagtgg atagcgcacg cgcccttatt gcccggggat
     1501 ggggagtaag cttcgtcagc cgttgtctcc gggtgtcgcg tgcgcagttg cacgtcattc
     1561 tcagacgagc cgatgactgg aaggacggcc gccgcagccg tcacacggat gatacggatg
     1621 tgcttcgccg tatacaccat gttatcggag agctacccac atatggttat cgtcgggtat
     1681 gggcgctgct tcgcagacaa acagaacttg atggtatgcc tgcgatcaat gccaaacgtg
     1741 tttaccggac catgcgccag aatgcgctgt tgcttgagcg aaaacccgct gtaccgccat
     1801 cgaaacgggc acataccggc agagtggctg tgaaagaaag taatcagcga tggtgctctg
     1861 acgggtttga gttccgctgt gataacggag aaaaactgcg ggtcacgttc gcgctggact
     1921 gctgtgaccg tgaggcactg cactgggcgg tcacaacggg tggcttcgac agtgaaacag
     1981 tacaggacgt catgctggga gcagtggaac gccgctttgg cagcgagctt ccggcgtctc
     2041 cagtggagtg gctgacggat aatggttcat gctaccgggc gaatgaaaca cgtcagttcg
     2101 ccaggatgtt gggacttgaa ccgaagaaca cggcagtgcg gagtccggag agtaacggaa
     2161 tagcagagag cttcgtgaaa acgataaagc gtgactacat aagtatcatg cccaaaccag
     2221 acgggttaac ggcagcaaag aaccttgcag aggcgttcga gcattataac gaatggcatc
     2281 cgcatagtgc gctgggttat cgctcgccac gggaatatct gcggcagtgg gccagtgatg
     2341 ggttaagtga taacaggtgt ctggaaatat aggggcaaat ccattgtcag cgccaacaat
     2401 gtgggctgac atgataaagc tgtctaggaa atcgttcgcc tcctcagcgg acaatccaaa
     2461 tggtgattgt ctctgttaaa cgtttatttt gaaggtcgac tgaataaggt gatgacgctg
     2521 tagaattttt cacgtgccac agaattttga acgctttctc ttacaatatt tcaatgtttc
     2581 tatcagtatt cgccggaaga agtcatcgac caaatcatcc cagtcgtctc gcaccactga
     2641 ccattcatgg ttgacatgtg gtggaaatcc gcttctacag taaccatttt ttattcgcaa
     2701 aaccgaacac gccatacgga tagctgttaa ctggcatgcc gaggcagtcg ttatttatat
     2761 ttagttttgt caataatctt tattttttgt aaaaggcaaa tataaattat tctcattatt
     2821 gtttgtattt atgtattgtc ttgccggtta acatgatcgg agattagtaa tatgcgaata
     2881 accactctgg cttccgtagt cattccctgt ctcggatttt cagccagcag catagctgct
     2941 gcagaggatg tgatgattgt ctctgcatcc ggctatgaga aaaagctgac taacgcagcc
     3001 gccagtgttt ctgtgattag ccaggaggaa ttgcagtcca gccagtacca cgatctggcg
     3061 gaggctctga gatcagtaga gggtgtggat gttgaaagtg gtacgggtaa aaccggtggg
     3121 ctggaaatca gcatccgagg aatgccagcc agttacacgc tgatactgat tgatggtgtt
     3181 cgtcagggcg gaagcagtga cgtgactccc aacggttttt ctgccatgaa taccgggttc
     3241 atgccccctc tggccgccat tgagcgtatt gaggttatca gggggccgat gtccacactg
     3301 tatggctctg atgcgatggg cggtgtggtg aatatcatta ccagaaagaa tgcagacaaa
     3361 tggctctctt ccgtcaatgc agggctgaat ctgcaggaaa gcaacaaatg gggtaacagc
     3421 agccagttta atttctggag cagtggtccc cttgtggatg attctgtcag cctgcaggta
     3481 cgcggtagca cacaacagcg tcagggctca tcggtcacat cactgagcga tacagcagcc
     3541 acgcgtattc cttatcccac ggagtcacag aattataatc ttggtgcacg tcttgactgg
     3601 aaggcgtcgg cgcaggatgt gctctggttt gatatggata ccacccggca gcgttatgat
     3661 aaccgggatg ggcaactggg gagtctgacg gggggatatg accggaccct gcgctatgag
     3721 cgaaacaaaa tttcagctgg ctatgatcat actttcacct tcggaacatg gaaatcgtat
     3781 ctgaactgga acgagacaga aaataaaggt cgtgagctcg tacgcagtgt actgaagcgc
     3841 gacaaatggg ggcttgccgg tcagccgcgg gagcttaagg aatcgaacct tatcctgaat
     3901 tcattactgc ttacccctct gggagaatct catctggtta cggtgggggg cgagtttcag
     3961 agctcgtcca tgaaagacgg agttgtcctt gccagcacag gtgaaacttt ccggcagaaa
     4021 agctggtcgg tatttgctga ggatgagtgg catctcacgg atgcacttgc gctgactgtg
     4081 ggcagccgct atgaacatca tgagcaattc gggggacact tcagtccgcg tgcatatctg
     4141 gtctgggatg tggcagatgc ctggacgctg aaaggcggtg tgaccacggg atataaggca
     4201 cccagaatgg ggcagctaca taaagggatt agtggtgtat ccgggcaggg aaaaacaaat
     4261 ctacttggta accccgacct gaagccggaa gagagcgtca gttatgaggc tggggtgtat
     4321 tacgataacc ccgccggtct gaatgccaat gtcacaggtt ttatgactga cttctccaac
     4381 aagattgtct cttattccat aaatgataac accaatagct atgtaaacag cggaaaggcc
     4441 cggttgcatg gtgtggaatt tgccggcaca ttgccgctgt ggtcagagga tgtcacgctg
     4501 tcactgaatt acacctggac ccgaagtgaa caacgtgatg gtgataacaa aggtgcgccg
     4561 ctgagttata cccctgaaca catggtgaat gcgaaactga actggcagat caccgaagag
     4621 gtggcatcat ggctgggtgc ccgttatcgc gggaaaacac cacgtttcac ccagaattat
     4681 tcgtcactga gcgctgtaca gaagaaagtg tatgatgaga aaggagaata cctgaaagcc
     4741 tggacggtgg tggatgcagg tctgtcgtgg aagatgacgg atgccctgac gctgaatgct
     4801 gcggtgaata acctgctcaa caaggattac agtgacgtga gcctgtacag tgccggtaag
     4861 agtacgctgt atgccggtga ttacttccag acgggatcat caacaacagg atatgtgata
     4921 cctgagcgaa attactggat gtcgctgaac tatcagttct gataataaca aaacgctatc
     4981 actgacggta gaatacgttg ccactgtaac tcctggcgga acagtggcaa cgtattaggt
     5041 taagtgcatt tccgatccgc taatgagatt tcgttaccaa caactaatat cgtcacagga
     5101 aatgcacgga ttatttttaa cttatcattt acatacttgt ccagagtgta agcgcaccgt
     5161 gaaggacgtg gggtaaaaat tagtgtacag agagagtgac gttccagggc aacaactctt
     5221 tcatgcggtt ggcaggccag gtgttgatta cactgatcac gtggcgtagc cacgtttccg
     5281 gctcgattcc gttaagtttt gcagctaccg atcaggctgt acatcactgc cgcactatcg
     5341 ctcgtcatct caaagtccgg tctcgtcagc aggaaggtat cattctctcc cgccattttt
     5401 ccgggggccc ggtcagataa gtccctttgt ctatcgctga ctcctggctc ataacccggt
     5461 tagcagaatg cagggtcacc acctcgccac gaccgaatcc ggataagtca attgcacctt
     5521 ctcaatcgcc attttgtcac aattaagttt gataaatcat gtcacctctg cactgaatct
     5581 gctccagtgc ctcattggtc tccgtccacc cctttaaact gccggataag actgctgcac
     5641 agcgccttcc ccggaatcaa atcactttcc ctgtccgcca caatccgctt catgccacct
     5701 cgtattttgt ttcagagacc ggaatctgcc agaaagtgac tacgcgtgca catatcggtt
     5761 ttctgggtta catgcatcgt gttattttct gaaatgcaaa ataataaaaa acaaggacac
     5821 ataatgaagg atgaaataca cagtaccagc atcaacccgg atgttgttga gcagtttctg
     5881 gcccttatga acacacattg taaatcctca gaagaggcgc tcgccatgct gagtacgctt
     5941 tgttacaacc tgatggtgac atgcggtatc cattccatgg acagccagat gctcaatggg
     6001 catgggatat ccatgcaact tcaggggatt gatattgccg aaaggccagg taagaatatt
     6061 cactaacctg aacagggtct gaaaacgctg tcttttcagg cctctgcagg caaaaactga
     6121 tgacaacaaa atttctgcgt ttgtacccca ccgatgaaaa agacaaaaac tcacaccggg
     6181 cttctagcca gtaaagataa aacccgacgt gtcagcctct acgaaacgcc aacggcatgg
     6241 tgtatcaggg ggcaggagtg ctacagcaaa agtacaggac gccgctgtgg cagccacgac
     6301 agtctgagca gactgcgcct ggacagcatt aagcctgttg aatgagtggt ggcaccatga
     6361 aagataacag cacaaccgcc accccagaag cctggaaaat gcgttttctg gccaacggga
     6421 catccggcac atggttttac actgacgaca ttacagtcac tgacgcgtgg cttcgcgcgc
     6481 acccggatga tgtggaggtt atccctctct gccggatacc accccgtcag cattcccatg
     6541 aacaacatat tgaagaactc cgtgcagccc tggcccggat gctgcatatg catcatatga
     6601 tgctggaaac cacgcattac agggaaaaca tcaccgatgc ccgttgtatc cgtgaaatgc
     6661 atgaagctcc attacaggcg ctcaatattc tggccagata cccgcacgag gtgtgacgca
     6721 tgtggctact gattttctgg ctttcatctc cctttaatgt ctcttccggt gatgcccggc
     6781 agcccacact ggcggtgcac agccaggcat ttcataccga acgggcctgt cgcgatgcat
     6841 tgcacgccat taaaaaggag aatgttggcg aattttctct gcggggcgtt tgtgtttctg
     6901 acggaaatac gaaggaggaa gctgagagct catgacggat attactgaca gacatacact
     6961 tcgccgtatg tcctggtcgg aactcttcac ggcagcacag gaagcggaat ttcagcgtga
     7021 ttacgagcgt gccagaatag tgtggtcatt cgccttacat gttgcaacaa ccacgattaa
     7081 caaaaatctg gccatagctc atattcgacg ctgcaatact ttgttgcata aatcaaaaac
     7141 agtacccgga aacaacacgg ggggccggtc agtgtgcctg agaccccaac atccccggag
     7201 atgactgaca ttccggactg acgcagttgc tgcatatctg tggcaatacg ttgtatccag
     7261 ccagacaggt tatcccgcgt agtgacaatt aacccgcttt cctgcaccag cttcagccgg
     7321 gccgtcgggg attttaccag ccggaaatat cagtaaaaca acatatcatt atgccatggt
     7381 gtacgcggcc agtgtacgct tacttaagga atgagggata aattggatat tattacttca
     7441 ctttgctttt ttatgagatt catcacataa gtggggtttt actgttaaat aatctgaatt
     7501 tatttgatat ccgtaaagca gatgtctcag ttcgctgttt ccaacttttg ttattcctct
     7561 ggggcgaatg ctgtttccgc tggaatattc acctggcacc agtcccagaa aagccatgag
     7621 ctgttcagga ttggaaaatc gcgaaaaatc acccagttca gcaaccaggg ttattgcgat
     7681 tagttgacca acacctttaa gagcctgcaa ctggcagacc agattgcaca gagatcactc
     7741 aggtaacagg cgagatattt cctgatcgag ttgaagtatg cgatcttcaa tctgctccag
     7801 attctgacaa taatgttgaa agcaatctgt tgagatagca gaccaaatga ttgagcgagt
     7861 gttagtgatg acaaacgtat ccaggtactt cttatctcat ggtgttttgg tggatttctt
     7921 gaggcggcag ccggatacgg tacagcggta gcaatcccca ttggtatact gattgctctg
     7981 ggctttaacc cactaaaagc agcgattgca tcactggttg ctaatacagt ccctacagcg
     8041 tttggggcag taggtatacc tgtctctgta cttgctgaac aagttaattt acctgtaacc
     8101 acactcagcg ggacaattat tcttcaactg gcactgttca acattctgct tcctttcgtc
     8161 atcgtcgcga ttatcggtgg tggtatgaag actatacgag gcgttggact aattaccctg
     8221 atgtgtggtg tcagtacatt aattccccag tatctggtgg ctgttaatct tggcgcggaa
     8281 ctcccggctt tcgcgggtag tcttgtcagt ctgatagtaa tagtctttat ggcgaaaaac
     8341 cgtaaagaaa aaaccgcccc tgaattgggg atgcggacga tttcctagac tgctttatta
     8401 tgccagccca cattgttggc ggtacatttc agggctgact gcacccagcg ataattttat
     8461 acgccgctcg ttataccatc tgatgtaagc atctacatgc tgcatgagct tttctggcgt
     8521 gatgcccgac catttacgcc cataatacat ttccgttttc agtctgccga aaaaaccttc
     8581 gcatgcggca ttatcaggtg aacatccttt acgggacatt gagcgaataa gacctgctgc
     8641 attcactctt tccagccagc ctggccagcg ataatgccca cctctgtcac tgtgtatcac
     8701 cggtcgttcg ccagcattta acgtttcgac agcgctatcc agcatagtgt tgaccagctc
     8761 agcatcgggg cgtgtactga gagaccagct aataactttt ccatcgaagc agtccaccac
     8821 cggtgacagc cagactttac ctgcagggag ttggaactcc gtgatatctg tcagccattt
     8881 ctgattaggt tgctacgcct taaaatctct ggcgataagg ttatccggag ccggtccgat
     8941 ttctccgcaa tatgagctgt agcgacgacg acggttacgg ctgacgacaa gctgttcctc
     9001 caccataagt ctgcgtacaa ccttttctga tagccgcccc ccctcatgcc tgagcatcgc
     9061 atgcaggcga cgatagccat aacactggta attactgtta aatatatctg tcagcatcgt
     9121 acgtatcgtg gcgtatttat caccggcttt cagtgcagcc cggtgataaa aataactgct
     9181 acgggtaagg cccagaacat gaagtaattc tgtcagggga tatgtttgcc tcagggcatc
     9241 agcgatcttt gttttttctc tgttgttcag gtgactgata ctgatgcccg ggtctttttt
     9301 tatgatttcc tccgcctttt tcagaatatc cagctccatc tgccggcggc gtatttcctg
     9361 attcagtcgg gcgacttcct cccgcaacgc atcgcgttct gcctccaggg aaggttcgtt
     9421 atgtttacgc atagtctggt aagcactgtt gccgataatt tcatctttct atttatacaa
     9481 taccgcacga ctgacaccaa tacgcctggc gatctcactg gctgatactt gtcgtgtaca
     9541 gagtgccatg acagcctgac gtttgacttc tggttcaaag ggcgcaaccg ggttggcctt
     9601 actggtaaat atacgtcgtc tgtcgggata aagttcatta acccagcgag cgagtacatc
     9661 agtgcaggga taacccaggg ctctgctggt aaacgccagg cagcagccgt ggttaagata
     9721 atgttcaacg gcaacctgtt tttgctcatc ggagtaacgg tgcttatgac gaatggattc
     9781 ttttgcgcca ccacctgctt cccatgagcg gatccaacgc cgcagatttc ttttcgaagg
     9841 gtagcccagt tcgcgtacga cgggagccag cttcttacca tatttgaaat aaagctcaat
     9901 ggcgcggatt ttttcttctt cagtaaacat gttttatctc ctgagagtcc aggaaatcgt
     9961 ccgcatcccc caacgagctg ctgtttaaat tcgggaggat aattagggca gccttttcgc
    10021 ctgccgggag tcacattttt ctgcatatct gacactttgg ttcccactac ttatttggtg
    10081 gacaccactt tgtctaattc gtcagattct gaccagacgg ttcaggctgt acgcttacag
    10141 ttgttcagga gtaatagtcc aaagtatcgg gaattttcca gacaatcctg ataatacgct
    10201 tatgaacatt acaacacgct catgcggaac ctggatgggg gaaggaacgg tgaagctgtt
    10261 agcgaatgac tggcgtttgt ataaacgccg gtcatgatga atgatatttc agaatatacc
    10321 tcgggctaaa ataccgggac agagatcagg catgattaat ctgcagcatt tttaataaca
    10381 gaagtactga gcttacttta cctttgatga tggaatagtt atttccgtcg gtacttattt
    10441 ttccctgaaa taatgtcacg gatgtttctt cctgctgatc ctgcaggcgc agtcgtaagg
    10501 tcatattttt aatgagctga gatccgggtg gcaaggggta tttgctgtca gatactgggc
    10561 gactgagtct gatgtggcgc gtatacagcc cgttttcgta cagggtggcc tctgttatgg
    10621 tgtcagtgac cagcatgtgg gagacaatgc tgtattcttt tttaaagcac ccaccagaaa
    10681 cggtgattgt aatgataatg gtcttctcga tcgagatgta aatacccgtt tcgttatact
    10741 gtccgtatcg gaaccatgag aactcagttt gaggtgtact ggcaatagcg gacac
//
LOCUS       DAPOXO010000132        10558 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.132, whole genome shotgun sequence.
ACCESSION   DAPOXO010000132 DAPOXO010000000
VERSION     DAPOXO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10558
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.132"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(53..502)
                     /locus_tag="ROH59_004601"
     CDS             complement(53..502)
                     /locus_tag="ROH59_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4806994.1"
                     /translation="MQRQYKKYILLFWGVMDVIAIATYLFYSLGNGRIPFYSDIVHSL
                     SLLKDIGVEGGFYAYAVATVTLQIVLLFSLFFSAQCFLRQKLFSFSFLAIQEFMRFAT
                     VSCSISVIPLLLNYFYSQDLVLNISLFIFSEVTKVTTIIWCKRQGKV"
     gene            complement(923..4606)
                     /gene="metH"
                     /locus_tag="ROH59_004602"
     CDS             complement(923..4606)
                     /gene="metH"
                     /locus_tag="ROH59_004602"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDX4806995.1"
                     /translation="MSSKVEQLCAQLNERILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVISAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPAEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPTELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANTQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKMLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKVSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     HRKGMSVTEVERWLAPNLGYDAE"
     gene            4807..5631
                     /gene="iclR"
                     /locus_tag="ROH59_004603"
     CDS             4807..5631
                     /gene="iclR"
                     /locus_tag="ROH59_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HDX4806996.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSNHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDRVTEFGAMVIKAAKEVTLAYGGIR"
     gene            complement(5648..7372)
                     /gene="aceK"
                     /locus_tag="ROH59_004604"
     CDS             complement(5648..7372)
                     /gene="aceK"
                     /locus_tag="ROH59_004604"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HDX4806997.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMAL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRR
                     QRFSVRFV"
     gene            complement(7497..8801)
                     /gene="aceA"
                     /locus_tag="ROH59_004605"
     CDS             complement(7497..8801)
                     /gene="aceA"
                     /locus_tag="ROH59_004605"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HDX4806998.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(8831..10432)
                     /gene="aceB"
                     /locus_tag="ROH59_004606"
     CDS             complement(8831..10432)
                     /gene="aceB"
                     /locus_tag="ROH59_004606"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HDX4806999.1"
                     /translation="MTEQATTIDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGRLPDFISETASIRDADWKIRGIPADLEDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEERNNQVLDKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
BASE COUNT         2489 a         2887 c         2617 g         2565 t
ORIGIN      
        1 catttaaaaa ggcatttata taaaaatcca cctgtatctg ttgctatttc tgtcacactt
       61 tcccctgtcg tttacaccag ataatcgttg tcacttttgt gacctctgag aagataaaca
      121 acgaaatatt taagaccaga tcctgtgaat aaaaataatt aagtaacaac ggtattacgg
      181 agattgaaca gcttacggta gcaaaacgca taaactcctg aatcgccaaa aaagagaaac
      241 taaataattt ttgtcttaaa aaacattgcg cagaaaagaa taaagagaac aataatacta
      301 tttgtagcgt aacagtggcg actgcataag cgtaaaaacc gccttcaaca ccgatatcct
      361 taagtaaaga aagtgaatga acgatatcgg aataaaaagg gatacgacca ttaccaagcg
      421 agtagaacag atatgtggct atcgcgataa catccataac accccaaaaa agaagaatgt
      481 attttttata ttgacgttgc ataaagtaaa tcctttttac gaaaacaaat attaccagga
      541 attattataa ttgcgggcgt ttttggatta acactccacc cgtatttttt aaacctctgt
      601 cagctatacc ttcactaaat aagacatcga tacgcccttt acttttatcg tgatacagaa
      661 tactgcatga gatacacctt ataccctctt tggatttacg aaaatctaac caataacgac
      721 catcataaaa tacccactcc acacctgttt tatattaatt atccaatcat tataacctgt
      781 tggttttttc ctaatagttc agtaacttcg gactctgaac atccttcgaa agcgaaaaaa
      841 tctatttcat caatttttat catattcaat aatccattat ttatgacatt aaaaaccggg
      901 gcaaataccc cggtgttatc acttactcgg catcataccc cagattcggt gccaaccaac
      961 gctcaacttc ggtaacgctc attcctttac ggtgggcata gtcttcaacc tgatcgcgct
     1021 gaatttgcgc caccgcgtaa tacttgctgt ctggatgact gaagtaccaa cccgaaaccg
     1081 atgcacccgg ccacatggcg aaagattccg tgagtttcat accggtatgt ttttccactt
     1141 ccagcagctc ccagattgtg gctttttccg tatgttccgg gcaggcaggg tagcccggtg
     1201 ccggacggat gccctggtag ttttcgcgga tcagctcttc gttgctgagg ttctcgttcg
     1261 gcgcatagcc ccagtagact ttacgcacac gctcatggag atactccgca aaggcttccg
     1321 ccagacggtc ggcaagcgct ttcaccatga ttttgttgta atcatcatgc tgtgcttcaa
     1381 aggcatcagc cagtgcgtcc tcttccagcc cgccagtcac ggcaaatgcg ccgatgtaat
     1441 ccgctttgcc ggaaaccttc ggcgcaacga agtcagcgag acagtagtta gcgaagccgg
     1501 ttttttcggt ctgttggcgc agatggtggc tgacattaat cacatgggta cgcgtttcgt
     1561 cacggtagat ttcaatgtca tcgcccacac ggtttgccgg gaacaggccc accacaccac
     1621 gcgggttcag cattttttcg gcgcttaatt tatccagcat gtcgttggcg tctttaaaca
     1681 gccgctgcgc ctcaacacct accacttcat cttccagaat gcgcggatac ttcccggcca
     1741 gcgaccaggt cataaagaac ggcgtccagt cgatgtaatt acgcagcgtt tcgatgctgg
     1801 cttcgacttc ctgcacaccg agacggtgcg ccaccggcgg cgtgtaagcc tgccagtcaa
     1861 aagcgaagtc gttatcacgc gccgcttcca gcgtgaccgg tggtgtgcgt ggtttctttc
     1921 gtccgtgctg aatacgcacg gtttcgtact ccttgcgggt acgagcaacg aaatcatcgc
     1981 gctgagtgtc ggaaagcagc gccgccacca caccaacggt gcgcgatgcg ttctgcacat
     2041 acaccgtcgg gccgctgtag ttctgctcga ttttcaccgc cgtgtgcgct tttgaggtgg
     2101 tcgcgccgcc aatcaatagc ggaatggtga agccctggcg ctccatctct ttcgccacgt
     2161 taaccatctc gtccagcgac ggcgtgatca gccccgaaag gccaatcaaa tcagcattca
     2221 cttctttagc ggtacggaga attttttccg caggcaccat cacgccgaga tcgacaattt
     2281 cgtagttgtt acattgcagc accacgccaa cgatattttt accgatgtcg tggacatcgc
     2341 ccttcactgt ggcgatcacc atcttgccgt tggttttacc ctgctctttg ctggcttcaa
     2401 taaacggctc gagatacgcc accgcctgct tcattacgcg cgccgatttc accacctgcg
     2461 gcaggaacat tttgccctcg ccaaacaggt cgccgaccac gttcatgccg tccatcaacg
     2521 ggccttcaat cacttcaatc gggcgcgtag cctgctggcg ggcttcttcg gtatcctgct
     2581 cgataaactc ggtaatgcct ttgaccagcg agtattccag acgtttattc acttcccacg
     2641 agcgccactc cgcctgctgg gtgttagcgg tgtcgtcggt tttgctgccg cgatatttct
     2701 cggcaagctc gagtaaacgc tcggtgccat cgtcgcggcg gttgaggatc acatcctcca
     2761 ccgcgtcgcg tagctcggta ggcaggtcgt cgtaaatcgc cagttgcccg gcgttgacga
     2821 tccccatatc catgccattg cgaatagcgt agtagaggaa caccgcgtga atggcttcgc
     2881 gcacaggatc gttaccacga aacgagaacg acacgttaga aacgccgccg gaaatcagtg
     2941 cgtgcggcag ttcacgtttg atgtcttcac acgcgccgat aaagtcctgt gcgtaattgt
     3001 tgtgctcttc aatgccagtt gcgaccgcga agatgttcgg gtcgaagatg atatcttcag
     3061 ccgggaagcc aacctcttcg gtgaggattt tgtacgcccg acggcaaatc tcgattttcc
     3121 gtgcgcgggt atcggcctgg ccctgttcgt caaaagccat taccactact gccgcaccgt
     3181 agcgacgcaa cagtttcgcg tgatggataa aggcgtcgac gccctctttc atcgagatag
     3241 agttaacaat gcctttgccc tggatacact tcagaccttt ttcaataacg tcccatttcg
     3301 aggagtcgat cattatcggc acacgagcga tatccggttc accggcaatc agattgagaa
     3361 aacgcaccat cgccgcttcg gcatcgagca tcccttcatc catgttgata tcgataatct
     3421 gcgcaccgtt ttccacctgc tgacgcgcca catccagcgc ctcgctgtat ttctcttctt
     3481 tgatcaggcg cttgaactta gcggaaccgg tgacgttggt gcgttcaccc acgttcacaa
     3541 acaggctatc ttcgccaatg ttcagcggct ccaggccgga caaacggcag gctacgggaa
     3601 tttccggtag tttgcgcggc gctaatcctt ctactgcacg actcatcgct gcaatatgtt
     3661 gtggcgtggt gccgcagcag ccgccgacga tattgagaaa gcccgcttct gcccattcac
     3721 gtatctgttt tgccatcgtg tcggcgtcga gatcgtattc accaaaggcg ttgggcagcc
     3781 cggcgttcgg gtgggcggtg acatagcatt ccgcaatacg cgacagttcc tgtacgtact
     3841 ggcgcagttc gtctggcccc agcgcacagt tcaggccaaa ggtcagcgct tcggcgtggc
     3901 gcagggagtt gtaaaacgct tcagtggtct gcccggagag cgtgcgcccg gaggcgtcgg
     3961 tgatggtgcc ggagatcata atcggcagtt caacgcccag cgcttcaaac tccgttttca
     4021 ccgcaaagac cgccgctttg gcgttaaggg tgtcgaaaac ggtttcaatc aggatcaggt
     4081 ccgcgccacc ttccaccagc gctttggtgg attctcgata agccgccacc agctggtcaa
     4141 aagtgatgtt gcggaatgcc ggatcgttga cgtccggaga aatagacgcc gtgcggttgg
     4201 tcgggccgag aacaccggca acgtagcgcg gtttctccgg cgtgcgggca gtccactcgt
     4261 cggcacaggc gcgcgccagt ttcgccgccg caaagttgat ttccgccgac agggattcca
     4321 tctggtaatc cgccatcgca atagtcgtgg agttgaaggt gttggtttcg atgatatccg
     4381 cacccgcttc aaagtaagcg ttgtggatgg cggagatcac ttccggtttg ctgagcacca
     4441 gcaggtcgtt gttgcctttg agatcgcatg gccagtcggc aaagcgttca ccacgaaaat
     4501 cggcttcgtt cagtcgatag ctctggatca tggtgcccat accgccgtcc agcaccagaa
     4561 tacgttcatt taactgcgca cacagttgtt ccactttgct gctcacactt gctcccgaca
     4621 cgcttaaccc agatttaata aaaattcaac aaaccatact ggcataaaca catctgtggt
     4681 aaaagcgacc accacgcaac atgagatttg ttcaacatta actcatcgga tctgttcagc
     4741 aactattgca ttcgctgata ataaaaatga aaatgatttc cacgatacag aaaaaaggag
     4801 actgtcatgg tcgcacccat tcccgcaaaa cgcggcagaa aacccgccgt tgccaccgca
     4861 ccagcgactg gacaggttca gtctttaacg cgtggcctga aattactgga gtggattgcc
     4921 gaatccaatg gcagtgtggc actcacggaa ctggcacagc aagccgggtt acccaattcc
     4981 acgacccacc gcctgctaac cacgatgcag caacagggct ttgtccgtca ggtcggcgaa
     5041 ctgggtcact gggcgatcgg cgcacacgcc tttatggtcg gcagcagctt tctccagagc
     5101 cgtaatttgt tagcgattgt tcaccctatc ctgcgcaatc taatggaaga gtctggcgaa
     5161 acggtcaata tggcggtgct tgatcaaagc aatcacgaag cgattattat cgaccaggta
     5221 cagtgtactc acctgatgcg aatgtccgcg cctatcggcg gtaaattgcc gatgcacgct
     5281 tccggtgcgg gtaaagcctt tctggcccaa ctgagcgaag aacaggtgac gaagttactg
     5341 caccgcaaag ggttacatgc ctatacccac gcaacgctgg tgtctcctgt gcatttaaaa
     5401 gaagatctcg cccaaacgcg caaacggggt tattcatttg acgatgagga acatgcgctg
     5461 gggctgcgtt gccttgcagc gtgtattttc gatgagcacc gcgaaccgtt tgccgcaatt
     5521 tcaatttccg gaccgatttc acgtattacc gatgaccgcg tgaccgagtt tggcgcgatg
     5581 gtgattaaag cggcgaagga agtgacgctg gcatacggtg gaatacgctg actttttcgc
     5641 ctctgattta tacgaatcga acgctaaacc gctgcctgcg ccgatacgca taaacatctt
     5701 ccacatgccc ttcacgtata cggttttgta gtgcgcgcca gtaatcagcg cggaacaagt
     5761 cggcgtgcat ctcttcaaat agcggaccaa tacgcgggtc ggcacataac cagtgacgga
     5821 actcttccgg gaaaacatcg cccggcgaga cgctgtacca cggttcgctg gcaagttcgt
     5881 cctccgggta gcgcggcggc gggatgtcgc ggaagttcac ttccgtcatg tagcaaattt
     5941 catcgtaatc ataaaacacc acacgcccgt gacgggtgac accgaagttt ttaaacagca
     6001 tgtcgccagg gaaaatgtta gcagcggcaa gctggcgaat agcgttaccg tattcttcaa
     6061 tggcatcgcg caactgctga ccttccactt gttccagcca gatattgagc ggcaccatcc
     6121 gccgctcaat ataaagatgg cgaatcacaa tttgttcgcc gagatcggtg attttttccg
     6181 ctgcttcctg gagcagtaat gccattaatg ccggggaaat atgccgcttc tccagcacaa
     6241 agttttcaaa ctcctgggtg tccgccattc ggcccacgcg atcgtgctct ttcaccagtt
     6301 ggtagcaggc gcgaacgtga gcggcagaca tctctttctg cggcgcgaac ttgtctttga
     6361 tcactttaaa tacccggtca aagcccggca gcgtgaacac caacatcacc attccacgaa
     6421 tacccggcgc ttcaatgaac tgctcattac agccctgtag ataaacgaga tattcgcggt
     6481 agctttcggt tttggcgtgc ttctggcagc cgatagccat atacaattca gcggtggttt
     6541 tacctggcag aatttcccgt agccactcga ccagcgctgc gggcagcggc gcgtaaacca
     6601 taaaataaga acgcgcaaag ccaaagacga tgctcgcttc ggcggtcgtc gtcagacagg
     6661 tatcaataaa taactcgccg tcgtccgtct ggtggatcgg cagcaaaaat ggcaatgtgc
     6721 cggaaggcgt gatcagtttg cccaccagcc aggcggcttt attgcggtaa aacagttcgt
     6781 tcgccacctg taaatgactt tccgcgaggt tgtctgtccc cagcgtttcc gttagatggc
     6841 gaacgatgta atgaatgtca cggcttttat tctgccagcg cagacgcaac ggcaggtcgc
     6901 tgataacgcg catcagcaga gattcccagc cgtgatcggg gtgaaagtct ttcgccagcg
     6961 ggcggggaat ggtacgaaaa cggcgctctg gctgggagct aaagataaaa agccgctcgg
     7021 gagtaagcga gcggtggtca aataaccgac agtacacgga gttaaaaaag ctctccgcaa
     7081 tctcgaagcg cgggtaatcc ggcaacagtc gggtgtaatg ctctttaacg cgcagtaaaa
     7141 atgccgcgtc cgtgctttgg ccgttagtaa tgcagcgcag ttgctccaca accagaccca
     7201 cgtgatgatc gtaaagatgg atacggtttt tcatcgcttg ctggacagcg tgccagtcgg
     7261 cttgttcgaa acgctgctgc gccccggaag tcacttcgag gaatcgacca tactgagcgt
     7321 cgaagccttg cagaatggtt tgtgcaatca gtaattccag gccacgcggc atttagcgcc
     7381 ctcatcagga gcagagaatt gccggataag acgcgcaaat cgtcgcatca ggcgttgatt
     7441 gccggatgcg gcgtgaacgc cttatccggc ctacaatcat caactttatc agttgcttag
     7501 aactgcgatt cttcggtgga gccggtcagc gcggtgactg aagacgtgcc gccctgaata
     7561 atggtcgtca ctttatcgaa ataacctgtc cccacttcct gctggtgaga tacgaaggta
     7621 tagccatctt tcgcggcggc aaattccggc tgctgcactt tctcaacata gtgcttcata
     7681 ccctcaccct gggcataggc gtttgccagg tcaaacatgt tgaaccacat gctgtggata
     7741 cctgccaggg tgatgaactg gaacttgtag cccatatccg acagctgctg ctggaagctg
     7801 gcaatagttt tgtcgtcgag gtttttctgc cagttgaacg acggcgagca gttataagcc
     7861 agcagtttgc ccggatattt cgcgtggatg gcttgtgcaa agcgacgcgc cagttccaga
     7921 tccggcgtgg aggtttcaca ccataccagg tcagcatatg gcgcatacgc caggccacgg
     7981 ctgatcgctt gctcaatacc cgcatgagta cggaagaagc cttcactggt acgctcgcca
     8041 gtaataaatt cgctgtcata tgggtcgcaa tcggaggtaa tcagatccgc cgcatcggca
     8101 tcggtacgag caaccagcag ggttggaacg cccgtcacat cagctgccag acgcgccgcg
     8161 accagtttct gaatagcttc ctgagttggc accaaaactt tgccgcccat gtgaccacat
     8221 ttcttcactg atgccagctg atcttcgaag tgaactgccg ctgcaccggc ttcaatcatc
     8281 gctttcatca gttcaaaggc attcagtaca ccgccaaaac cggcctccgc atcggcgacg
     8341 atcggcagga agtaatcgac atagcgcgga tcgcccggct caatgcccgc ggaccattgg
     8401 atctgatccg cacggcggaa agtattgttg atccgctcta ccacagctgg caccgagttt
     8461 gccggataga gcgactgatc cggatacatg ctggccgcca ggttagcgtc cgccgctacc
     8521 tgccatcccg acagatagac tgcttcaata cccgctttcg cctgttgcaa cgcctgaccg
     8581 ccagtcagtg caccgaggct gttgatgtag ccttttttcg actcgccgtg cagcagacgc
     8641 cacattttcg ccgcgcccag ttgcgccagg gtgcattccg gattgactga accgcgtaat
     8701 ttcaccacat cttccgcgct gtacgggcga gtaatgcctt cccaacgcgg ttgagtccac
     8761 tctttctgta attcttcaat ttgttgtgta cgggttttca tgtgcagatg ctccatagtt
     8821 atgtggtggt ttacgctaac aggcggtagc ctggcagggt caggaaatca attaactcat
     8881 cggaagtggt gatctgttcc atcaagcgtg cggcatcgtc aaaacgcccc tgggagaaac
     8941 gttcttcgcc cagttcgctg gcaatgactt tcatctcttc gcccagcatc tggcggaaca
     9001 aggctttagt caccggtttg ccattgctca acgttttttg atgatggatc cactgccaga
     9061 ttgaggtacg ggaaatttca gccgtcgccg catcttccat caggccataa atcggcacac
     9121 agccattgcc agagatccac gcttcgatgt actgcacagc cacgcgaatg ttggcacgca
     9181 taccttcttc ggtgcgttca ccatcacaag gtgccagcag ctgatcggca gtaatcggcg
     9241 cgtcttgttc gcgcatcacc tcaagctggt ttttgcggga gccgagaata tcgttgaata
     9301 ccgccattgc cgtatcagca aggcccgggt gagcgatcca tgtgccatcg tgaccgttat
     9361 tggcttccag cgatttatcc gcttttactt tgtcgagcac ctggttattg cgctcttcat
     9421 ctttgctcgg aataaacgcc gccatgccgc ccatcgcaaa agcaccgcgt ttatggcagg
     9481 ttttaatcaa caggcgtgag taagcattca ggaagggttt atccatcgtc actgcctgtc
     9541 tgtctggcag gacgcgatcg ggatagtttt tcaatgtttt gatataactg aagatgtaat
     9601 cccaacgacc gcagttcaga ccaacaatat ggtcacgcag cgcgtgaagg atttcatcca
     9661 tctggaacac ggcgggcagc gtttcaatca gcaacgtcgc cttgatggtg ccgcgcggca
     9721 gattaaagcg atcttctgca tagctgaaga cttcgctcca ccaggccgct tcctgccagg
     9781 actgggtttt cggcagatag aaatagggac cgctgccctt tgccaacagt gcctgatagt
     9841 tgtggaagaa atagagcgca aaatcaaaca ggctaccggg gattgcctca ccacgccagg
     9901 tgacatgttt ttccggcaag tgcagaccgc gtacccgaca aatcaaaacc gctggattgg
     9961 gcttgagctg ataaattttg cctgcttcat tggtatagct gatggtgccg ttaactgcat
    10021 cgcgcaggtt aatttgccca tcgatcactt tgttccagtc tggtgccagt gaatcttcga
    10081 aatcggccat aaagactttc acattggcgt tgagcgcgtt gatcaccatc ttgcgctcta
    10141 caggtccggt aatctctacg cgacgatctt ctaagtccgc aggaatcccg cgaattttcc
    10201 agtcagcatc acgaatggaa gctgtttccg aaatgaaatc aggcaacctt ccgttatcga
    10261 tatcctgctg ctgctgaatg cgcgctgcca gaagtttatt gcgttgtggc gtaaaatgcg
    10321 tcaccagctc agtcagaaat tctaccgctt cggcagtaag aatttgcttc tcctgctcgc
    10381 catacggcct tgtgaaagcc agttcatcga ttgttgttgc ctgttcagtc atcgtgcagc
    10441 tcctcgtcat ggatccgaaa acttccccac tgtgaacgaa ggatcgttgt gcgcttttcg
    10501 ttcagcacaa ctaagactac tcatttaaaa tgcaaaatca aaaacaattt ccatttta
//
LOCUS       DAPOXO010000133        10481 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPOXO010000133 DAPOXO010000000
VERSION     DAPOXO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10481
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.133"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..127)
                     /locus_tag="ROH59_004607"
     CDS             complement(<1..127)
                     /locus_tag="ROH59_004607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein RepA"
                     /protein_id="HDX4807000.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKK"
     gene            complement(1302..1943)
                     /locus_tag="ROH59_004608"
     CDS             complement(1302..1943)
                     /locus_tag="ROH59_004608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807001.1"
                     /translation="MNADTWTRLQAFRHALELTSCEASLTAGYDHLKDFPAGCSELAS
                     QTLTDYLTEDGSNLYSCIVGMQWDNGPGRYGHVIADPARDYIDLTLDQFPGYHNRIVA
                     EPVESGGQLAADLNREPAISTADGIVASPSDKVNYITEQKNRQPMVIITECYKLIRMT
                     ARFIPMCQSSQLFQHQVFPRLFIISDVGSCSLFRNTLDRLATDWKVTLSILSL"
     gene            4265..4483
                     /gene="ccdA"
                     /locus_tag="ROH59_004609"
     CDS             4265..4483
                     /gene="ccdA"
                     /locus_tag="ROH59_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HDX4807002.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTMQNEARRLRAERW
                     KAENQEGMAEVARFIEMNGSFADENRDW"
     gene            4485..4790
                     /gene="ccdB"
                     /locus_tag="ROH59_004610"
     CDS             4485..4790
                     /gene="ccdB"
                     /locus_tag="ROH59_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HDX4807003.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            4791..5597
                     /locus_tag="ROH59_004611"
     CDS             4791..5597
                     /locus_tag="ROH59_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HDX4807004.1"
                     /translation="MSGSVIHSQSAVMVPAVYSAGQPASLPVAIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLAPPYPF
                     VQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVAMLKQLS"
     gene            6371..7126
                     /gene="repE"
                     /locus_tag="ROH59_004612"
     CDS             6371..7126
                     /gene="repE"
                     /locus_tag="ROH59_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="HDX4807005.1"
                     /translation="MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVD
                     QIRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEED
                     AGDEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNP
                     YAMRLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINS
                     RTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG"
     gene            7714..8880
                     /gene="sopA"
                     /locus_tag="ROH59_004613"
     CDS             7714..8880
                     /gene="sopA"
                     /locus_tag="ROH59_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="HDX4807006.1"
                     /translation="MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGE
                     AADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAE
                     DVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDL
                     HIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPT
                     DPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQ
                     FFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRE
                     TDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
     gene            8880..9851
                     /locus_tag="ROH59_004614"
     CDS             8880..9851
                     /locus_tag="ROH59_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition
                     protein"
                     /protein_id="HDX4807007.1"
                     /translation="MKRAPVIPKHTLNTQPVGDTSLSTPAAPMVDSLIARVGVMARGN
                     AITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDSLDDLIPSFLLTGQQ
                     TPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSA
                     YERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSA
                     RSGDALQKAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLS
                     SRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEKPAP"
BASE COUNT         2636 a         2317 c         2577 g         2951 t
ORIGIN      
        1 tttttttact gttcttcagt gacttaaggg taggtacaaa gacgcccaga cgcatcagcg
       61 ccacaggttg tacggtgttg ttattgtttg gtgtcagtgt caccagctca ccggacgact
      121 tatccacctc gccgaacagt tttttgatgt ctgaattttc gttttccaga aagcctcctg
      181 cctgtggaca gtaaaagaat aaacagaaaa tcgtgtgtca gaaccccgtc aactgactga
      241 agaaaaacct gcagtctgta tttaacaact gagtctggcg tactgaccat agtttatgtc
      301 attaacttac ttcagtatat gcattactga atacagctta tcatgaacct gttacagttt
      361 atccataaca tgccacagct tatgtgaacg tggtcccggc ccatgagtga caaggtttgc
      421 agcgatatgg ggatctttaa tggatccttt gttgatcatt catggatctg tttactggat
      481 cgggcctctg gatatgtgga taaatcattc cggaaaaaca acatacacta ccgattatga
      541 aggcttcagg gcgtacctgc tcactgtaac tacagatata ttgcgcttcc tcgccggttc
      601 gcgggcttcg cccggtcacc ggtctgcggc gagcactgtt ttttctgaag tctgtcttta
      661 caggtaattt ttgacggaat ctgccgtact tcctgagcgt acagtcatat ccgaaataca
      721 cttcatatgt ttgtctcaac gccagaggcg catgcagact ggctccatga atatcctgac
      781 aactggcatc acttaattta ccgacagtct taagactaat cgtcagaatc ctgataattg
      841 acgtttcagg tccagagaag tgcagacgtt gcaaccagtc agctgtgcct gtgtcggagc
      901 tgatatccgt gatgaagcaa accaaagagc tgtagcatca gttgggcaaa acgagctact
      961 gtaaaaagcc gttggaccga caaaataagt gaatatcgta tatgcctttg ctgccggagg
     1021 atgacagaat aaaccctgtc agttattgac tctggatctt acgagcccaa ctgtatgcca
     1081 taatctgtcg gtcgaaagag tgacaggatc ctgatgacag gcactgctgc gcagacaccg
     1141 gtcatggatg taatggaaat accagctgaa ccgcaggtct tccagtcggg gacacagagt
     1201 acagggctgg agcttgtgga tacgtatctc tggatcttca aacactttat tgaaggaaag
     1261 gagttaacca gatcccttgc ctgccaggtt tatatcaagc cctatagcga caggatggac
     1321 agtgtcacct tccagtcagt agctaaacga tctaaggtgt tcctgaacaa actgcaggag
     1381 ccaacgtctg aaatgataaa taagcgaggg aatacctggt gctggaagag ttgagatgac
     1441 tggcacattg gtataaatct tgccgtcatt ctgatcagct tgtaacattc tgtaatgatc
     1501 accattggct ggcgattttt ctgttcagta atgtaattaa ccttatctga tgggctggcc
     1561 actattccat cagctgtact gatggcaggc tccctgttga ggtctgccgc gagctgtccg
     1621 ccggactcaa cgggctctgc cacaatccgg ttatgatagc ctggaaactg atcaagggtt
     1681 aggtcgatat agtccctggc agggtcggca atgacgtggc cgtatctgcc aggaccatta
     1741 tcccactgca taccgacaat acaggagtac aggttgctgc cgtcttccgt cagataatca
     1801 gtcagcgtct ggctggccag ctcgctgcaa ccggccggga aatccttcag gtgatcatac
     1861 ccggcggtga gagaagcctc acaggaagtc agctccagag catgtcggaa ggcctgcagg
     1921 cgggtccagg tgtccgcatt cactttttcg ccttcccgtc atgacgggcc agggactgaa
     1981 gtttacggac gtcctcccgg gatcctttca gctcagcttt cgtatccagc aggtgcgccg
     2041 ccagcggtct ttttcccggg agccgacttt cctggcacat attcttttcg cagttatccc
     2101 cagaatctgt ggataactgt tgctcctctt ttgagagaga aggctttact caccgcctga
     2161 atgcggcaga tatgtctgga cgatatatct gcatacgccg gtactgcttc gtcagattgc
     2221 acggcaggtg aattgccggg ctggtaccat accatatttg cgccgaaccc gtccggggcg
     2281 gtgccgataa cagatgttaa atgattggtc gtttttacat ctgtaaaagc aacagggccc
     2341 catgattata tcatggggcc ctgttactct gattcttcgc aatagattgc tctgaattaa
     2401 ttggtgttta tctgtatttt ttgttttcgg aacgtttttg taagaattat cttttatatt
     2461 tgaggtgata tcttattgtg gttgttgtaa tagtttagag tcgtaataaa tatgattgat
     2521 cgccacttta aatgaagtta atctactgga gatgaagtaa cttcattaat gcgtcataaa
     2581 aataaaaatt cctgttttgg gaaatatgaa tgtgtctgtc ccctccttcg ggagggtgtt
     2641 ttttatctgg aaactggttt ctggttctga tttttctttt tgtattatag cgagttacgc
     2701 atatttacca atcgatgtct ggcaaacaga gtatggcgat ggtgtgattt gtgtttattg
     2761 gtaaaaaaaa cacccccgta gtgggggtgt tgagacttca acctatgaac tcattatcct
     2821 gggatggatg agtagcgtgc gatattgaat catattcagc aggaataata atattcgcaa
     2881 aaaaatggat gtgcaaggaa attttttata tgcttttgtg tgtggtggtt aggtaatcaa
     2941 gaagataaat gatgaagtgt gccagttcag gatcaatgtt tccatgggaa agtcatttat
     3001 taataatatc aattaagttc gaaagctcag ggaagatttg ttcaatgttt tcctctgtct
     3061 cccgcacagt catatagcga cgtctccttg gggattgaaa acaaaaacaa taatacaaca
     3121 agtatgtaac agaaggtagg tggcaggggc ggaacaggaa aacgcatgag ggcgcttcct
     3181 gggggagatg cctggtatct ttagggttca gttttgagat cgggaatttt tgtacattaa
     3241 gtgcattatt taatcaattg aaacgcgtaa tggattgatt ttatcagcaa ctatcgcgtt
     3301 taagttgtcg atcatatttg agttgtctca ttaaggtcga atcccctgaa agcggcgtat
     3361 aacgtaggag ttcccctcta tagcaatagg taaggctgtt caaaaaaggc ttaccgtaca
     3421 ataattcgct aggcccccct tgtcatacaa gctcgtaagc ggccctgacg gcctgtcaat
     3481 gcggtactgc cctgtcggga ctgctctacc cacataagtt tctacatagc ttgaagctgg
     3541 atggggaggt attacggctt tagccgtaat actttcttcg tcctcgcagc gctgacagtt
     3601 ttcagggatc aaatttaggt ccgccataca ctccgtaaag actctgtcag ttcacaggta
     3661 ttacctagtg aagacgtatc ataaaatgaa aactgtagtt gggtagttgc tccccctcac
     3721 ggcatgcagg ggctgagggg gaaaatttcc ttatcttgtt gttgctattt ctggcttagt
     3781 cagttttgaa ttttgcttcc taagcaataa tcccctcacc gcaacaatcg ttcttctaca
     3841 ctaataagat ccgaaaaaag gtagttacgg atcttcctct ccctccgcac agcgttacat
     3901 cccgtcagca cagcatgtag tgcctcatac agttgccaat ggcactatat gttgtgttgt
     3961 atctctggac tgtgatgcgc cgcgcagggg cggaaaacag cgatatgatg attttctcag
     4021 cgttgtacac ttccggaaag tcgtttattc aaataaagtc ggatccatac gaaacgggaa
     4081 tgcggtaatt acgctttgtt tttataagtc agattttaat ttttattggt taacataacg
     4141 aaaggtaaaa tacataaggc ttactaaaag ccagataaca gtatgcgtat ttgcgcgctg
     4201 atttttgcgg cataagaata tatactgata tgtatacccg aagtatgtca aaaagaggtg
     4261 tgctatgaag cagcgtatta cagtgacagt tgacagcgac agctatcagt tgctcaaggc
     4321 atatgatgtc aatatctccg gtctggtaag cacaaccatg cagaatgaag cccgtcgtct
     4381 gcgtgccgaa cgctggaaag cggaaaatca ggaagggatg gctgaggtcg cccggtttat
     4441 tgaaatgaac ggctcttttg ctgacgagaa cagggactgg tgaaatgcag tttaaggttt
     4501 acacctataa aagagagagc cgttatcgtc tgtttgtgga tgtacagagt gatattattg
     4561 acacgcccgg gcgacggatg gtgatccccc tggccagtgc acgtctgctg tcagataaag
     4621 tctcccgtga actttacccg gtggtgcata tcggggatga aagctggcgc atgatgacca
     4681 ccgatatggc cagtgtgccg gtctccgtta tcggggaaga agtggctgat ctcagccacc
     4741 gcgaaaatga catcaaaaac gccattaacc tgatgttctg gggaatataa atgtcaggct
     4801 ccgttataca cagccagtct gcagtcatgg taccggcagt gtattctgcc gggcagcctg
     4861 catcgctgcc tgttgccatt gattatccgg cagctctggc acttcgccag atgtcgatgg
     4921 tccatgatga actgccaaaa tatctgctgg ctccggaagt gagtgccctg ctccattacg
     4981 tcccggatct gcaccgcaag atgctgctgg ccacactgtg gaacaccgga gcacgcatta
     5041 atgaagcact ggcgctgacg cggggggatt tttcgcttgc gcctccgtat ccgtttgtgc
     5101 agcttgcgac cctgaaacaa cggaccgaaa aagctgccag gacggcgggg agaatgcccg
     5161 ccggtcagca gactcaccgg ctggttccgc tctctgactc ctggtacgtc agccagctgc
     5221 agacgatggt ggcaacactg aaaataccca tggagcggcg taaccgtcgc acaggaagga
     5281 cagagaaagc gcggatctgg gaagtgacgg acagaacggt caggacctgg attggggagg
     5341 cggttgccgc cgctgctgct gacggtgtga cgttctctgt tccggtcaca ccacatacgt
     5401 tccgccattc ctatgcgatg cacatgctgt atgccggtat accgctgaaa gttctgcaaa
     5461 gcctgatggg acataagtcc atcagttcaa cggaagtcta cacgaaggtt tttgcgctgg
     5521 atgtggctgc ccggcaccgg gtgcagtttg cgatgccgga gtctgatgcg gttgcgatgc
     5581 tgaaacaatt atcctgagaa taaatgcctt ggcctttata tggaaatgtg gaactgagtg
     5641 gatatgctgt ttttgtctgt taaacagaga agctggctgt tatccactga gaagcgaacg
     5701 aaacagtcgg gaaaatctcc cattatcgta gagatccgca ttattaatct caggagcctg
     5761 tgtagcgttt ataggaagta gtgttctgtc atgatgcctg caagcggtaa cgaaaacgat
     5821 ttgaatatgc cttcaggaac aatagaaatc ttcgtgtggt gttacgttga agtggagcgg
     5881 attatgtcag caatggacag aacaacctaa tgaacacaga accatgatgt ggtctgtcct
     5941 tttacagcca gtagtgctcg ccgcagtcga gcgacagggc gaagccctcg agtgagcgag
     6001 gaagcaccag ggaacagcac ttatatattc tgcttacaca cgatgcctga aaaaacttcc
     6061 cttggggtta tccacttatc cacggggata tttttataat tatttttttt atagttttta
     6121 gatcttcttt tttagagcgc cttgtaggcc tttatccatg ctggttctag agaaggtgtt
     6181 gtgacaaatt gccctttcag tgtgacaaat caccctcaaa tgacagtcct gtctgtgaca
     6241 aattgccctt aaccctgtga caaattgccc tcagaagaag ctgttttttc acaaagttat
     6301 ccctgcttat tgactctttt ttatttagtg tgacaatcta aaaacttgtc acacttcaca
     6361 tggatctgtc atggcggaaa cagcggttat caatcacaag aaacgtaaaa atagcccgcg
     6421 aatcgtccag tcaaacgacc tcactgaggc ggcatatagt ctctcccggg atcaaaaacg
     6481 tatgctgtat ctgttcgttg accagatcag aaaatctgat ggcaccctac aggaacatga
     6541 cggtatctgc gagatccatg ttgctaaata tgctgaaata ttcggattga cctctgcgga
     6601 agccagtaag gatatacggc aggcattgaa gagtttcgcg gggaaggaag tggtttttta
     6661 tcgccctgaa gaggatgccg gcgatgaaaa aggctatgaa tcttttccct ggtttatcaa
     6721 acgtgcgcac agtccatcca gagggcttta cagtgtacat atcaacccat atctcattcc
     6781 cttctttatc gggttacaga accggtttac gcagtttcgg cttagtgaaa caaaagaaat
     6841 caccaatccg tatgccatgc gtttatacga atccctgtgt cagtatcgta agccggatgg
     6901 ctcaggcatc gtctctctga aaatcgactg gatcatagag cgttaccagc tgcctcaaag
     6961 ttaccagcgt atgcctgact tccgccgccg cttcctgcag gtctgtgtta atgagatcaa
     7021 cagcagaact ccaatgcgcc tctcatacat tgagaaaaag aaaggccgcc agacgactca
     7081 tatcgtattt tccttccgcg atatcacttc catgacgaca ggatagtctg agggttatct
     7141 gtcacagatt tgagggtggt tcgtcacatt tgttctgacc tactgagggt aatttgtcac
     7201 agttttgctg tttccttcag cctgcatgga ttttctcata ctttttgaac tgtaattttt
     7261 aaggaagcca aatttgaggg cagtttgtca cagttgattt ccttctcttt cccttcgtca
     7321 tgtgacctga tatcgggggt tagttcgtca tcattgatga gggttgatta tcacagttta
     7381 ttactctgaa ttggctatcc gcgtgtgtac ctctacctgg agtttttccc acggtggata
     7441 tttcttcttg cgctgagcgt aagagctatc tgacagaaca gttcttcttt gcttcctcgc
     7501 cagttcgctc gctatgctcg gttacacggc tgcggcgagc gctagtgata ataagtgact
     7561 gaggtatgtg ctcttcttat ctccttttgt agtgttgctc ttattttaaa caactttgcg
     7621 gttttttgat gactttgcga ttttgttgtt gctttgcagt aaattgcaag atttaataaa
     7681 aaaacgcaaa gcaatgatta aaggatgttc agaatgaaac tcatggaaac acttaaccag
     7741 tgcataaacg ctggtcatga aatgacgaag gctatcgcca ttgcacagtt taatgatgac
     7801 agcccggaag cgaggaaaat aacccggcgc tggagaatag gtgaagcagc ggatttagtt
     7861 ggggtttctt ctcaggctat cagagatgcc gagaaagcag ggcgactacc gcacccggat
     7921 atggaaattc gaggacgggt tgagcaacgt gttggttata caattgaaca aattaatcat
     7981 atgcgtgatg tgtttggtac gcgattgcga cgtgctgaag acgtatttcc accggtgatc
     8041 ggggttgctg cccataaagg tggcgtttac aaaacctcag tttctgttca tcttgctcag
     8101 gatctggctc tgaaggggct acgtgttttg ctcgtggaag gtaacgaccc ccagggaaca
     8161 gcctcaatgt atcacggatg ggtaccagat cttcatattc atgcagaaga cactctcctg
     8221 cctttctatc ttggggaaaa ggacgatgtc acttatgcaa taaagcccac ttgctggcct
     8281 gggcttgaca ttattccttc ctgtctggct ctgcaccgta ttgaaactga gttaatgggc
     8341 aaatttgatg aaggtaaact gcccaccgat ccacacctga tgctccgact ggccattgaa
     8401 actgttgctc atgactatga tgtcatagtt attgacagcg cgcctaacct gggtatcggc
     8461 acgattaatg tcgtatgtgc tgctgatgtg ctgattgttc ccacgcctgc tgagttgttt
     8521 gactacacct ccgcactgca gtttttcgat atgcttcgtg atctgctcaa gaacgttgat
     8581 cttaaagggt tcgagcctga tgtacgtatt ttgcttacca aatacagcaa tagtaatggc
     8641 tctcagtccc cgtggatgga ggagcaaatt cgggatgcct ggggaagcat ggttctaaaa
     8701 aatgttgtac gtgaaacgga tgaagttggt aaaggtcaga tccggatgag aactgttttt
     8761 gaacaggcca ttgatcaacg ctcttcaact ggtgcctgga gaaatgctct ttctatttgg
     8821 gaacctgtct gcaatgaaat tttcgatcgt ctgattaaac cacgctggga gattagataa
     8881 tgaagcgtgc gcctgttatt ccaaaacata cgctcaatac tcaaccggtt ggagatactt
     8941 cgttatcgac accagctgcc ccgatggtgg attcgttaat tgcgcgcgta ggagtaatgg
     9001 ctcgcggtaa tgccattact ttgcctgtat gtggtcggga tgtgaagttt actcttgaag
     9061 tgctccgggg tgatagtgtt gagaagacct ctcgggtatg gtcaggtaat gaacgtgacc
     9121 aggagctgct tactgaggac tcactggatg atctcatccc ttcttttcta ctgactggtc
     9181 aacagacacc ggcgttcggt cgaagagtat ctggtgtcat agaaattgcc gatgggagtc
     9241 gccgtcgtaa agctgctgca cttaccgaaa gtgattatcg tgttctggtt ggcgagctgg
     9301 atgatgagca gatggctgca ttatccagat tgggtaacga ttatcgccca acaagtgctt
     9361 atgaacgtgg tcagcgttat gcaagccgat tgcagaatga atttgctgga aatatttctg
     9421 cgctggctga tgcggaaaat atttcacgta agattattac ccgctgtatc aacacagcca
     9481 aattgcctaa atcagttgtt gctctttttt ctcaccccgg tgaactatct gcccggtcag
     9541 gtgatgcact tcaaaaagcc tttacagata aagaggaatt acttaagcag caggcatcta
     9601 accttcatga gcagaaaaaa gctggggtga tatttgaagc tgaagaagtt atcactcttt
     9661 taacttctgt gcttaaaacg tcatctgcat caagaactag tttaagctca cgacatcagt
     9721 ttgctcctgg agcgacagta ttgtataagg gcgataaaat ggtgcttaac ctggacaggt
     9781 ctcgtgttcc aactgagtgt atagagaaaa ttgaggccat tcttaaggaa cttgaaaagc
     9841 cagcaccctg atgcgaccac gttttagtct acgtttatct gtctttactt aatgtccttt
     9901 gttacaggcc agaaagcata actggcctga atattctctc tgggcccact gttccacttg
     9961 tatcgtcggt ctgataatca gactgggacc acggtcccac tcgtatcgtc ggtctgatta
    10021 ttagtctggg accacggtcc cactcgtatc gtcggtctga ttattagtct gggaccatgg
    10081 tcccactcgt atcgtcggtc tgattattag tctgggacca tggtcccact cgtatcgtcg
    10141 gtctgattat tagtctggga ccacggtccc actcgtatcg tcggtctgat tattagtctg
    10201 ggaccacggt cccactcgta tcgtcggtct gattattagt ctgggaccac gatcccactc
    10261 gtgttgtcgg tctgattatc ggtctgggac cacggtccca cttgtattgt cgatcagact
    10321 atcagcgtga gactacgatt ccatcaatgc ctgtcaaggg caagtattga catgtcgtcg
    10381 taacctgtag aacggagtaa cctcggtgtg cggttgtatg cctgctgtgg attgctgctg
    10441 tgtcctgctt atccacaaca ttttgcgcac ggttatgtgg a
//
LOCUS       DAPOXO010000134        10452 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.134, whole genome shotgun sequence.
ACCESSION   DAPOXO010000134 DAPOXO010000000
VERSION     DAPOXO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10452
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.134"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            43..777
                     /gene="nanR"
                     /locus_tag="ROH59_004615"
     CDS             43..777
                     /gene="nanR"
                     /locus_tag="ROH59_004615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HDX4807008.1"
                     /translation="MSDNKKTVLPGLTTTRKPIVTKKLSEIVAEELERMIRQEEIREG
                     EYLPSERELMAFFGVGRPSVREALSSLRHKGLIRYNKGEKASVCRPSPETIINGLSGI
                     VKDFLSTADGIKDFERLRIFFETNLVRYAAKNATPEDIHRLEKVLSIHHNSLRTPEVY
                     AQYDIEFHSILADIPDNKVLKTIHSAFSEWLIMAKPLEKNKMTYENNKKTHQQHIEIL
                     TAIKEHDCDKAEQLMYNHLYKRIEAS"
     gene            complement(813..1748)
                     /locus_tag="ROH59_004616"
     CDS             complement(813..1748)
                     /locus_tag="ROH59_004616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001305022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4807009.1"
                     /translation="MGFIMNKDRSLNEMMLSLFNKSTIVDLSSETISESKSLSGRIYQ
                     DPEHNGEFELDRVLTDIYAPQLIIFLPDKPNGTGILIIPGGGYQAVMLDKEGTALAPE
                     FLSQGYTLFVLSYRLPSPVEGENINKTFIDAISAMLYIRKNADKWHLQRHRIGVLGFS
                     AGGHIASTFVNQICDFKRSSDSKEQEIFAIPDFVGLIYPVISMKDDVTHPGSRKQLLG
                     DNSTSENIIQYSADLNVTSCFPPVFLLHCCDDDLVSIENSLLMYRGLIEKGVSAEMHL
                     YEKGGHGFSIQWATDLSVGGWIKLFMDWMYSHGFK"
     gene            complement(1798..2907)
                     /locus_tag="ROH59_004617"
     CDS             complement(1798..2907)
                     /locus_tag="ROH59_004617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HDX4807010.1"
                     /translation="MKVKNFIYLPFCLFIGTSVAGALPEIPEPFKYGVGGIENGKIYI
                     GLGSLGNNWYMIDTNQSEKKWTKIAQWPTVPREQATATIIDGKIYVFGGIGKDKSGVI
                     TLQKDVYSYDIAKDKWEKLMTRPPVSLAGHVSFIHNGHAVSTGGVNENIFNGYFSDVE
                     LSKGNSALTEKVNRDYFSKPADDYFLNNHIISYDPSKNQWKNLGTTPFPGTAGSSVIF
                     AEQQIYILGGERKPGLRSVRSWTGELSHDRIKWSELPPVASPEGVSGAYASVIDGNIF
                     LAGGAYFPGAAEKYSNGEYWSHKGLDKAYSKEIYQLIKNDWKKVGSLPEGLAYGVSLP
                     WQGGMLILGGEKKDGKAVSDVIYLKKNDKQIKIVK"
     gene            complement(2920..3630)
                     /locus_tag="ROH59_004618"
     CDS             complement(2920..3630)
                     /locus_tag="ROH59_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002431274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid channel protein"
                     /protein_id="HDX4807011.1"
                     /translation="MKKYYPLLTVILLGLPLCSQALTLNLRGGYRSASHAYETLIQVS
                     QGWNNGWWASFESNTWNTIHNNENELFALNYNKIDINKTYKIDDKWALIPGIQTQWMS
                     AGSQYNPYLKISYQATPDLNLALRYRYDWKAFRQTDLDGNRARNDQHQFDGYVTYKIN
                     DSWLFAWQTTVYTKVNNFKYGNHKKTATENAFVLQYKMSPVFTPYIEYDYLDKQGVYK
                     GKDNKHENSYRVGVLINF"
     gene            complement(3676..4506)
                     /locus_tag="ROH59_004619"
     CDS             complement(3676..4506)
                     /locus_tag="ROH59_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000948499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4807012.1"
                     /translation="MLSGNKKMIHYRENIYSLDNYERYITDSSLFENTGDGIIYTGIV
                     PLITVVEPVVSNQHSVLIIPGGGYRRIVYEREGLDVGRWIAGQGYTAFILSYRMPSVN
                     GYYSFADAKNALNFISYWAGMSERTFKSVGCMGFSAGGHLAGYITHLHYEEETSVRPD
                     WMALIYPVISLDRSIAHQGCRKRLLDAGESEYSASLENSVTEYMPPVFIVHATDDKDV
                     PVIHSLRYFNSIRDKGHHAEAHFFDKGGHGFGVSGKNGYPIEKWQSLLLEWLAEHKFH
                     "
     gene            complement(4510..5982)
                     /locus_tag="ROH59_004620"
     CDS             complement(4510..5982)
                     /locus_tag="ROH59_004620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4807013.1"
                     /translation="MDSCIQKKQVWYKHLSPRQWKIFGAAWTGYLLDGFDFVLISLVL
                     TEVQHEFGLTTIEAASLISAAFISRWFGGLAIGALSDKMGRRMAMVLSIVLFSLGTLA
                     CGLAPGYAVMFIARIVIGLGMAGEYGSSVTYVIESWPVHLRNKASGFLISGFSIGGGL
                     AAQVYSIVVPLWGWRSLFFVGMLPILFAFYLRKNLPESDDWQKRQQENKPVRTMVDIL
                     YREKNKYINILLSCIAFACLYVCFSGVTANAALITVMALCCAAVFISFIYQGMGKRWP
                     TGIMLMLVVMFCFLYGWPLQAFLPTWLKVDMQYSPETVALIFMLAGFGSAAGSCIGGF
                     MGDWLGTRKAYVISLLIGQLVIIPVFLVDRDYVWLLGLLIFTQQVFGQGIGALVPKII
                     SGYFNVEQRAAGLGFIYNVGSLGGACAPILGAVVASHTSLGTAMCSLAFILTFVVLVL
                     IGFDMPSRVQRWIHPEAALEYDTVDGKPFYGARKKNVAEE"
     gene            complement(6031..6906)
                     /locus_tag="ROH59_004621"
     CDS             complement(6031..6906)
                     /locus_tag="ROH59_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000629094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HDX4807014.1"
                     /translation="MITLAVDIGGTKISAALISDDGSFLLKKQISTPHERCPDEMTGA
                     LRLLVSEMKGTAERFAVASTGIINNGVLTALNPDNLGGLKEYPLKNIMEDITGLNGSV
                     INDAQAAAWAEYTVLPKEICDMVFITVSTGVGGGIVVNRKLLTGVSGLAGHVGHILSG
                     VTDTECGCGRRGCVEAVSSGRAIMGAAKNKLAGYSTKYIFELARQGYKEAEFLTERSA
                     STIAELIVSLKLLLDCQVVVVGGSVGLADGYVQKVSKHLSIYSEICNVMLFPAYFRSD
                     SGLIGATLWDRDCIT"
     gene            complement(6940..7857)
                     /locus_tag="ROH59_004622"
     CDS             complement(6940..7857)
                     /locus_tag="ROH59_004622"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDX4807015.1"
                     /translation="MQCEFKGVISALPTPYDQSQQIDMESLRKLIRFNIEQNIKGLYV
                     GGSTGEAFLQNVAEREKILETVADESDGRLTLIAHVGGISTAESEVLAKAAKKYGYHA
                     ISAVTPFYYPFSFEEHCIHYRKIIDSADGLPMVVYNIPALSGVRFSLDQINELVTIPR
                     VCALKQTSGDLFQMEQIKRNHPELVLYNGYDEIFASGLIAGADGGIGSTYNIMGWRYL
                     EIFEAVKNNDVIKAKEMQVACNQVIDTLIQSGVLAGIKTLLYYMGIINTPVCRSPFSP
                     VKEKNLDVLSKLAERLFEEHDRNKKMKII"
     gene            8009..8146
                     /locus_tag="ROH59_004623"
     CDS             8009..8146
                     /locus_tag="ROH59_004623"
                     /inference="COORDINATES: protein motif:HMM:NF024407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HDX4807016.1"
                     /translation="MQCPVTILCVTLCDYLAPELITHSPEESDTVTLRKRRLPLEMMA
                     W"
     gene            8518..8943
                     /locus_tag="ROH59_004624"
     CDS             8518..8943
                     /locus_tag="ROH59_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX4807017.1"
                     /translation="MEQKILSAEPRRTFSNEFKLQMVKLASQLGASVARIAREHDIND
                     NLLFKWLRLWQNEGRISRRLPVTTSSDAGVELLPVEITPDEQKEPMAALTPLLSTPSQ
                     STVSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
     gene            8940..9290
                     /gene="tnpB"
                     /locus_tag="ROH59_004625"
     CDS             8940..9290
                     /gene="tnpB"
                     /locus_tag="ROH59_004625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX4807018.1"
                     /translation="MISLPSDTRISLVAGVTDMRKSFNGLGEQVQHVLDENPFSGHLF
                     IFRGRRSDMIKILWADADGLCLFTKRLEEGLFIWPAVRDGKVSITRSQLAMLLDKLDW
                     RQPKTSRLNALTML"
     gene            9321..10418
                     /locus_tag="ROH59_004626"
                     /pseudo
     CDS             9321..10418
                     /locus_tag="ROH59_004626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT         3165 a         2508 c         1925 g         2854 t
ORIGIN      
        1 taaattaaaa actcatttgc tctaatccat ataaatcaat atatgtccga caacaaaaaa
       61 accgtgttac ccgggctaac aacgaccaga aagcccattg ttacaaaaaa actttcagaa
      121 atcgttgccg aagagcttga aagaatgatc cgccaggagg agataaggga aggtgaatac
      181 ctgccttctg aacgtgaact tatggcattc tttggcgttg gaagaccatc tgtcagagag
      241 gctttatcat ctctcagaca taaagggcta atccggtata acaagggaga aaaagccagt
      301 gtctgccgtc catcaccaga aaccatcatt aatgggttat caggcattgt taaagatttt
      361 ttatctacag ctgatggcat caaggatttt gaaagactac gcatcttttt tgaaaccaac
      421 cttgtaagat atgcagcaaa aaatgcaacg cctgaggata ttcacaggct tgagaaggtg
      481 ctcagtatcc atcataactc actgagaacc cccgaagtgt atgctcaata tgatattgaa
      541 tttcatagta tacttgctga tatacctgac aataaagtat taaaaacaat acactcagca
      601 ttttctgaat ggctgataat ggccaaacct ctggaaaaga ataaaatgac atatgaaaat
      661 aacaaaaaaa cccatcagca gcatattgaa atacttacgg ccataaaaga gcatgattgt
      721 gataaagctg aacagctaat gtataatcac ctttataaac gaattgaagc atcatagtta
      781 ctcgacgctt caccaggtag tcaccataaa tattatttaa atccatgaga atacatccag
      841 tccataaaca gttttatcca tcctccaaca gaaagatctg tggcccactg aatactaaaa
      901 ccatgccctc ctttctcata gagatgcatt tcagcagaaa cgcctttctc tattaggcca
      961 cggtacatga gcagactgtt ttcaattgac acaagatcat catcacaaca atggagtaaa
     1021 aacacaggag gaaaacatga tgtgacatta agatccgcac tatattgtat tatattttct
     1081 gaggtactat tgtcccccag taattgcttc ctggagcctg gatgtgtcac atcatctttc
     1141 attgatatta caggataaat taacccgaca aaatcgggaa tagcgaaaat ctcttgttct
     1201 ttactgtcag aagaacgttt gaaatcacaa atctgattca caaacgttga ggcgatatgc
     1261 cccccagcag aaaatcctaa tacaccaata cgatgacgct gtagatgcca tttatcagca
     1321 ttcttacgaa tataaagcat tgcagatatt gcatcaataa aagttttgtt tatattttct
     1381 ccctcaactg gcgatggtaa tctgtaacta agaacaaata atgtatagcc ctgagataaa
     1441 aactctggag caagagctgt accttcctta tctaacataa cagcctggta gccccccccg
     1501 ggaataatca atattcctgt tccatttggt ttatctggta aaaaaataat taactgagga
     1561 gcataaatat ctgtcaatac acgatcaagt tcaaattccc cgttatgttc aggatcctga
     1621 taaatacggc ctgaaagaga tttactctca gatattgtct cacttgacaa gtcaacaata
     1681 gttgatttat taaacaagct taacatcatt tcatttaaag atctatcttt attcattata
     1741 aaccccatta aaataactca ggtgactgaa caactaatac agtcacctgc attacagtta
     1801 tttaacaatc tttatttgtt tgtcattttt tttcagataa ataacatctg aaacagcttt
     1861 accatctttt ttctcccccc ccagaatgag catccccccc tgccagggca ggcttacacc
     1921 ataagcaagt ccttccggca aagaaccaac ttttttccag tcatttttta ttagctgata
     1981 tatctctttt gaataggctt tatccagtcc tttatgagac cagtattcac cattgctata
     2041 cttttctgcc gcccccggga aatatgcacc accggccaga aagatatttc catcaataac
     2101 agaggcatat gctcctgaca ccccctcggg tgaagctact ggtggaagtt cagaccattt
     2161 aattcgatca tgcgaaagct cccccgtcca ggatctaaca gaacgaagcc ccggttttct
     2221 ctcccctccc agtatataaa tttgctgttc tgcaaaaatc accgatgaac cagcagttcc
     2281 cggaaatgga gtcgttccca ggttcttcca ctggtttttt gacgggtcat aagaaattat
     2341 atgattattt aaaaaataat catcagcagg tttactaaaa taatccctgt tgactttctc
     2401 tgtcagcgcg gaattccctt ttgataactc gacatctgaa aagtatccat taaaaatatt
     2461 ctcatttaca ccaccagtag ataccgcatg accattatgg ataaaagaaa catgaccggc
     2521 aagagataca gggggacggg tcatcaattt ttcccattta tctttagcaa tatcatagga
     2581 atagacatct ttttgtaagg ttatgactcc acttttatct tttccaattc ctccaaatac
     2641 atagatctta ccatcaataa tagtagctgt tgcctgctct ctgggaactg tcggccattg
     2701 cgctatctta gtccattttt tttcactctg gtttgtatct atcatatacc agttatttcc
     2761 cagacttcct agtcctatat atattttacc attctcgatc cctcctacac catatttaaa
     2821 tggttcagga atttccggta aagctccggc taccgacgtt ccaataaaca agcagaaggg
     2881 aagatatata aagtttttca ctttcattgt aatcaccttt taaaaattaa tcagaacacc
     2941 gacacggtaa ctattttcat gtttattatc tttcccctta tacacccctt gtttatccaa
     3001 gtaatcatat tctatatatg gggtgaacac cggtgacatt ttatattgca gaacaaatgc
     3061 attttcagtt gctgtttttt tatgattccc atatttgaaa ttattaacct tcgtatatac
     3121 cgtggtctgc catgcaaaca accatgaatc attaattttg tatgtcacat aaccatcaaa
     3181 ctgatgctga tcattacgcg ccctgttgcc atctaaatcc gtctgtcgga aagctttcca
     3241 gtcatagcga tagcgtaagg ccagattaag atctggcgtt gcctgatacg aaattttcag
     3301 ataagggtta tactgacttc ctgctgacat ccattgtgtc tgaatccctg ggattagagc
     3361 ccatttgtca tctattttat atgttttatt tatatctatt ttattataat tgagtgcaaa
     3421 caattcattt tcattgttgt gaattgtatt ccaggtgttt gactcaaaac ttgcccacca
     3481 accattattc cacccctgac taacctgaat caacgtttca taagcgtgac tggcgcttct
     3541 gtatccccca cgtagattaa gagttaatgc ctgagagcac aaaggtaaac caagaagaat
     3601 tacagttaat agtggataat attttttcat aaatgcctca tcattaaata tatttatcac
     3661 ttgtaatttg atttctcaat gaaacttatg ttccgcaagc cattccagaa gcaggctttg
     3721 ccatttttct atcggatatc cattttttcc ggatacacca aatccatgac ctcccttatc
     3781 aaaaaaatga gcttctgcat gatgtccctt atcccgaata gagttaaaat atctcagaga
     3841 atgaataact ggaacatcct tatcatctgt tgcatgcaca ataaagactg gtggcatata
     3901 ctctgtaaca ctattttcaa gactggctga atattcactt tcacctgcat ccagaagacg
     3961 tttccggcat ccctgatgag caatactcct gtcaagagat ataactggat atatcagagc
     4021 catccagtca ggacgcacag aagtctcttc ctcataatgg agatgagtaa tatatccagc
     4081 aagatgacca cctgccgaaa accccataca tccaacactc ttaaatgttc tctccgacat
     4141 tccggcccag taagaaataa agttcagggc attcttcgca tctgcaaagg aataataacc
     4201 attaacggag ggcattctgt aagaaagaat aaatgccgta tatccctgac ctgctatcca
     4261 tctgccaaca tcaagtccct ctctttcata aacaatcctc ctgtatccac ctccaggtat
     4321 aatcagcaca ctatgttgat tagatacaac aggctcaaca actgtaataa ggggcacaat
     4381 acctgtatat attatgccat cgccagtatt ctcaaatagc gaactgtcag ttatgtaacg
     4441 ctcataatta tcaagagaat atatattctc cctgtaatga atcatttttt tattccctga
     4501 tagcatccgt tattcttctg caacattctt ttttcttgct ccataaaaag gttttccatc
     4561 gacagtatca tattcaagcg cagcttctgg atggatccat ctctgtacac gtgatggcat
     4621 atcaaaacca ataaggacaa gaacaacaaa tgttaagata aaagcaagag aacacattgc
     4681 tgtaccaaga cttgtatgag acgcaacaac tgcaccaaga ataggcgcac atgctccacc
     4741 aagtgaacct acattataaa taaaccccag tcctgccgca cgctgctcca cattaaaata
     4801 accactgatt attttcggca ccagagcacc aatcccctga ccaaaaacct gctgagtaaa
     4861 gattagaagg ccaagtaacc atacatagtc ccggtccaca agaaaaacgg ggataataac
     4921 aagctgaccg ataagaagtg atataacata tgcttttcgg gttccaagcc agtcccccat
     4981 aaaaccacct atacaacttc cagctgcaga gccaaaacct gccagcataa atatgagagc
     5041 aacagtttct ggtgaatact gcatatcaac cttaagccat gtaggaagaa aagcctgcag
     5101 tggccatccg tagaggaaac agaacataac cacaagcatc aacataatgc ctgttggcca
     5161 tcttttcccc ataccctgat atataaaact gataaaaaca gccgcacagc acaatgccat
     5221 aactgtgatt aaagcagcgt ttgcagtgac gcctgaaaaa caaacatata gacatgcaaa
     5281 tgcaatacaa gacagaagaa tatttatgta tttattcttt tctctgtaca gaatatccac
     5341 cattgttctg acgggtttat tctcttgttg ccttttttgc cagtcatcag actccggaag
     5401 attcttgcga agataaaaag caaataatat tggaagcatg ccgacaaaga aaagagaacg
     5461 ccagccccat agtggtacta caatgctata aacctgtgca gctaaacctc ccccaataga
     5521 aaatccagaa attaaaaaac cacttgcctt gtttctgaga tgaacaggcc agctttcgat
     5581 aacatatgtt acacttgagc catattcacc tgccatacca agcccaataa caatgcgagc
     5641 aataaacatc actgcatatc caggagccag accacaggca agggttccga gagagaatag
     5701 cactatactt aaaaccattg ccatcctgcg ccccatcttg tccgataaag cgccaatagc
     5761 aagcccccca aaccatcgag aaataaaagc agcggaaata aggcttgccg cttctattgt
     5821 cgtcaagccg aattcatgct gaacctctgt aagaaccaga gatatcagaa cgaaatcaaa
     5881 accatcaagt aaataacctg tccatgccgc accgaatatc ttccactgtc tgggtgaaag
     5941 atgcttatac caaacctgct ttttctgaat acaggagtcc atattaaacc tcacaataat
     6001 agcggattta taatacactg gagtattact ttaagtaata caatcccggt cccaaagagt
     6061 tgcaccaata agaccagagt cacttctgaa atatgcagga aacagcatta cattacaaat
     6121 ttcagaatat atggaaagat gtttcgacac tttctgaaca tacccatcag caagtccaac
     6181 acttcctccg acaacaacaa cctgacaatc aagcagtaat tttaaactta ctattaattc
     6241 agcaatagta ctggcagaac gctctgtcaa aaattctgct tccttatatc cctgtctcgc
     6301 taattcaaaa atatatttgg tgctatatcc tgcaagttta ttttttgctg cccccatgat
     6361 ggcccgacca gatgaaaccg cttcaacgca tccccgacga ccacatccac attctgtatc
     6421 cgttactccg gacaatatat gcccaacatg tccggctaat ccagaaacac ctgttaataa
     6481 ttttctgtta actacaattc cccctccaac ccccgtagaa acggttataa aaaccatatc
     6541 acaaatttct ttcggcaaaa ctgtatattc tgcccatgcg gctgcctggg catcatttat
     6601 cacacttcca tttaaaccag ttatatcttc cattatattt ttcagaggat actctttcag
     6661 ccctccaaga ttgtctggat tcagagctgt caatactcca ttattaataa tccctgttga
     6721 tgctactgca aatcgctccg ctgttccctt catttcagaa accagtagac gtaaagcccc
     6781 tgtcatttcg tcaggacatc tttcatgagg tgttgatatc tgttttttca gcaaaaatga
     6841 accgtcatca gatatcaacg ccgctgaaat tttcgttcct cctatatcaa cagccagtgt
     6901 tatcattcat tttcacctat ataacaatct tgcaattatt cagattattt tcattttttt
     6961 gtttctgtca tgttcttcga acagtcgctc tgcaagtttt gataatacat ccagattctt
     7021 ttcctttacc ggagaaaaag gacttctgca tacaggagta tttataatcc ccatatagta
     7081 aagaagagtt tttatacctg ccaggacacc actctgaata agagtgtcaa taacctggtt
     7141 acaggctact tgcatttcct tcgccttaat cacatcattg tttttgactg cttcaaatat
     7201 ttcaagataa cgccacccca ttatattata tgtactaccg attcccccat ctgcacctgc
     7261 aattaaccct gatgcaaata tttcatcgta accattatat aacacaagct ctggatgatt
     7321 ccttttgatt tgttccatct ggaataaatc accggatgtc tgttttaatg cacaaaccct
     7381 gggtattgtg acaagctcat ttatctgatc taaagaaaaa cgcactccgc taagagccgg
     7441 tatattataa actaccatcg gaagtccatc tgcagaatca ataatcttcc tgtaatggat
     7501 acaatgctct tcaaatgaaa aaggataata aaatggagta acagcagata tagcatgata
     7561 tccgtatttt tttgcagctt ttgcaagtac ctcgctttct gccgtactga ttccgcccac
     7621 atgcgctata agtgtcagtc ttccatctga ttcatcggct actgtttcaa gaattttttc
     7681 tcgctctgca acattctgaa gaaatgcttc tccagtagag cctccaacat acaatccctt
     7741 aatattttgt tcgatattaa aacggatcag ttttcgaaga ctctccatat cgatttgctg
     7801 ggattggtca taaggagtgg gtaatgctga tatgacccct ttaaattcac attgcatttt
     7861 taatcacctt cacttaactg cataatggga tacctagtac accatcaagt acaaagatta
     7921 tccaacagaa aagaagcaca atgtgaagat tatcaaaaaa aaaccatcag aaagctgtca
     7981 tgccgctcag ttaaggatcg gttgatcgat ccagtgtcca gttactattc tctgcgtaac
     8041 cctctgcgac tatcttgccc cggaactgat tacccacagc cctgaagagt ccgacactgt
     8101 cacgctacgc aaacggcgtc ttcctctgga aatgatggcc tggtgaatta tcagtatggc
     8161 ccatgagcgt aaggaacctt caccagattg tgaaccggct ggacacatgc tgccaggtag
     8221 tcgccccttt gtcgcgccgt gatccatgcc cagcagggcc aggaagcggg gccgtacgcc
     8281 acgtgttcac gtaaacagcg cagccctgac ataacaccac gctgtatccg ctctggtgca
     8341 atatgaacct gctgaccatc gatggcgtgt tctaactaac acaggacacg ccagaacacg
     8401 acataaagct tcactcgcca gatacatggt aagcgtaaac tgaccgccgt atgtagccat
     8461 taagccagta ttggtaacgt aggtgcccac cttttcatca actagtggac acctgttatg
     8521 gaacagaaaa tattatccgc agaaccccgc agaacatttt caaatgagtt taaacttcaa
     8581 atggttaaac tggcttcaca actaggagcc tctgttgccc gtattgccag ggaacacgat
     8641 atcaatgata acctcctgtt caaatggctc aggctctggc agaacgaagg gcgtatatcg
     8701 cggcgtcttc cggtaacaac ctcttctgac gctggcgttg aattattacc tgttgagata
     8761 acgcctgatg agcagaaaga gcctatggcg gctcttactc cgcttttatc cactccttca
     8821 caaagcacag tcagtgccag ttcctgtaaa gttgagttcc gccacggtaa catgacgctg
     8881 gaaaatcctt caccagagct gctcacggtg ttgatccgtg aactgaccgg gagggggcga
     8941 tgatctcgct cccatcagac actcgaatct cgctggttgc cggcgttact gatatgcgta
     9001 aatccttcaa cggtctgggt gaacaggtac aacatgtgct ggatgagaac cccttctccg
     9061 gtcacctgtt catcttccgt ggccgacgga gtgacatgat taaaatcctc tgggctgatg
     9121 ctgatggtct gtgcctgttc accaaacgcc tggaggaagg cctgtttatc tggcctgcgg
     9181 tgcgtgacgg taaggtatcc attacccgct cgcagctggc aatgctcctc gataagctgg
     9241 actggcgtca gccaaaaaca tcccgtctta acgcactgac aatgttgtaa aaatgtcatg
     9301 gccggattat aaaaacggtc atgagtcgga aatacctcat tcgtatcact gagctggaaa
     9361 ggctgctctc tgagcaggct gaagccctcc gtcagagaga tctgcaactg agtctggttg
     9421 aagagacgga ggccttcctg cgctctgcac tggcacgtgc cgaagaaaag atcgaagagg
     9481 aggagcggga aatagaatat ctgagggccc agatagaaaa actgcgccgg atgctgttcg
     9541 gtacccgttc tgaaaaactg cagcgtgagg ttgaacaggc tgaggcccaa ctgaaacaac
     9601 gcgaacagga aagcgatcgt tacagtgggc gtgaggatga cccgcaggtt ccccgccagt
     9661 tgcgacagtc acgtcatcgt cgtccgttac cagcacatct tccccgtgaa atacaccgcc
     9721 tggagcctga agaaagttgt tgcccggagt gtggcagtga gctggattat ctgggtgaag
     9781 tcagtgctga gcagctggaa ctggtgagta gcgccctgaa agtgatccgc actgttcggg
     9841 taaaaaaagc ctgtacaaaa tgtgactgta tagttgaagc gccagcgccg tcccgcccga
     9901 tagcgcgcgg catcgcgggc tccggattac ttgcccgcgt gttaacggga aaatactgcg
     9961 aacacctgcc actgtatcgt cagagtgaaa tctttgcccg acagggtgcc gaactgagcc
    10021 gtgcattaat ctccaactgg gttgacgcgt gctgccagtt aatgactccg ctaaatgatg
    10081 ccctgtaccg ttacgtgatg aacacccgca aggttcacac tgacgacaca ccggtaaaag
    10141 tgctgacacc gggcagaaaa aaggcaaaaa caggacgcat ctggacgtat gtccgggatg
    10201 accggaatgc gggctcatca gagccaccgg cggtctggtt cgcctactca ccagacaggc
    10261 agggaaaaca tccggtacaa caccttcgtc ccttccgggg tatcctgcag gcggatgcat
    10321 tcagcggtta cgatcggctg ttcagtgcca aacgtgaagg tgatgcacag acagaagttg
    10381 cgtgctgggt ccatgcccgg cgaaaaatac acgatgtatg aacgacatct cttctgacga
    10441 cattttcctg ct
//
LOCUS       DAPOXO010000135        10197 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPOXO010000135 DAPOXO010000000
VERSION     DAPOXO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10197
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.135"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1643)
                     /locus_tag="ROH59_004627"
     CDS             complement(<1..1643)
                     /locus_tag="ROH59_004627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDX4807019.1"
                     /translation="MWNLLRRTRKNQKSGRDVREAGWTSLFQAVAEPFSGAWQQGVKA
                     DPEAVLSFHAVFACISLISQDIAKMRLRLMQTDAHGIRRETRRGDIARLCRRPNAQQN
                     RIQFFELWLNAKLRHGNTVVLKIRNARGQIKELRILDWSRVEPLVADDGEVFYRITPD
                     RNCGITEAVTVPAREVIHDRFNCFFHPLIGLPPVYAAGLAATQGHHIQENSTSFFRNG
                     GRPSGVIEIPGSITEENAKKLKSNWDSGYTGENAGKTAILSNGAKYNPTTFSPVDAQT
                     VEQLKMTAEIVCSVFRVPAYKIGVGQPPSSDNVEALEQQYYSQCLQTLIESIELLLDE
                     ALETGENESTEFDVTTLLRMDSERRMKTLGDAVKNTLLTPNEARKRENLPPLAGGDAL
                     YLQQQNYSLEALSRRDAREDPFASAGKTVSSQLPDGASDGNKAISETEHDAVKAMFRG
                     DTEKMTERELSIIRALGEEFSTVLADLQRTFEGKMASQAQAFEEKLTSLSAVLQKHVT
                     VDEVRPVLQAMVDDAVGAIPVPRDGRDYDPDVLQQAVNDA"
     gene            complement(1589..1810)
                     /locus_tag="ROH59_004628"
     CDS             complement(1589..1810)
                     /locus_tag="ROH59_004628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807020.1"
                     /translation="MAKIRYLQGTHDARAGDIRDVAQPCAEVLVRLGKAEYITVRRPA
                     GQKKKRDAEHGECGTFYGEPEKTRNQDVT"
     gene            complement(1855..3792)
                     /locus_tag="ROH59_004629"
     CDS             complement(1855..3792)
                     /locus_tag="ROH59_004629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDX4807021.1"
                     /translation="MTLKRACSLLTVKSFSEDERVITGIASTPSPDRDGDILEPEGAE
                     FGSAIPFLWQHDHSRPVGQCTVRRVSEGLEITATLVKPVPDMPSQLAARLDEVWAAIK
                     TGLVRGLSVGFRPHEYTFLDGGGLHFLRWELMEVSAVTVPANAECTIRTIKSYDRPFS
                     AASGNRKPVVKIASSAGAAAQSTTVFHKEKTIMNIGEQIKSFENKRAALAASLEEVMT
                     KAAEEGRTLDVEEEEHYDNTAAEIRQVDAHLKRLRELEAGKAATAQPVKQAGNGNVAA
                     VASAPVIRVEQKLDKGIGFARFAKSLAAAKGVRSEALEVARRQYPDDSRLHHVLKSAV
                     GAGTTTDPQWAGSLSEYQEYAQDFIDYLRPQTIIGRFGQGGIPALRQVPFNIRVHAQV
                     SGGAAGWVGEGKAKPLTKFDFESITFSHAKVSAIAVLTEELIRFSSPAADALVRNALA
                     EAVVARLDTDFVDPKKAAVADVSPASITHDVKGTASTGNPDADAEAAFGQFVAANLQP
                     TGAVWLMSSTNALALSMRKNALGQKEYPDMTLLGGSFQGLPVIVSQYVGDQLVLVNAP
                     DIYLADDGGVAVDMSREASLEMQSEPTGDSTTPSPVELVSMFQTGSVAIRAERWINWR
                     RRRTAAVAVITGVNYGSASGG"
     gene            complement(3856..5517)
                     /locus_tag="ROH59_004630"
     CDS             complement(3856..5517)
                     /locus_tag="ROH59_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDX4807022.1"
                     /translation="MIPVWSTACPDWAERLKKGLSIIPDPIYPDEAAHALAIFKQLRI
                     VDAPGSPTFGESCAPWVFDLVAALFGSYDAQTGVRHIKEVFILIPKKNSKSTLAAGIM
                     MTALLLNWRQAAGYTILAPTVEVAANAFNPARDMVRRDDDLDDLCQVQTHIRTITHRV
                     TDTTLKVVAADPNTVSGIKSVGTLIDELWLFGKQCKAEDMLREAIGGLASRPEGFVVY
                     TTTQSNEPPAGVFRQKLQYARDVRDGKIHDPHFLPVIFEHPPEMVESGTNLLMENLAM
                     VNPNLGYSVDEAFLYREYRKAREAGEETFRGFMSKHANVEIGLALRSDRWAGADFWEE
                     QGRCISLDDILRRADVVTVGIDGGGLDDLLGMYVIGRDRETREWLGWGHAWAHETAVV
                     RRKSEASRFQDLVACGDMTIVRRVGDDTAEVAEYVRRIHEAELLDHIGIDPSGVGQIL
                     DSLAEAGIPDGIVVGISQGWKLGGAIKTTERKLAEGVLVHGDQPLMAWCVGNARVEPK
                     GNAILITKQASGRGKIDPLMALFNAVSLMSLNPEPKKKEYAVFFI"
     gene            complement(5514..6077)
                     /locus_tag="ROH59_004631"
     CDS             complement(5514..6077)
                     /locus_tag="ROH59_004631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDX4807023.1"
                     /translation="MLTTQKRKFALALMSGKNKTASAIAAGYSAKTARVKGSQLAKDP
                     EVLAFIARKQCETVEVDEVPVYRQKKSEQEDKPRRREAAAIPQPDENNLEMPPSAVMS
                     PGIEYMEDGLPDPVKAMGRILVENLCIDPKLALDAAWRLAQFTHHKKGDTGKKSAKGD
                     AAKKAANRFAVPPPPRLVVNNDNEGNG"
     gene            complement(6368..6733)
                     /locus_tag="ROH59_004632"
     CDS             complement(6368..6733)
                     /locus_tag="ROH59_004632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDX4807024.1"
                     /translation="MAELRTLQSRIKTLNTRRVNILKGEQRRVSGSARVSLKRHIWLR
                     DAGQCCICGRVVDLCDSELDHRIALQFGGGNEETNLWTLCAECHRQKSAREAASGMPD
                     PTLPEVSGGSGREDDIIGL"
     gene            6775..6975
                     /locus_tag="ROH59_004633"
     CDS             6775..6975
                     /locus_tag="ROH59_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HDX4807025.1"
                     /translation="MSSKNRTRRTTTRNIRFPNHIIEQINIALEHKGSGNFSAWVIEA
                     CRRRLATDATHLRPASMTNNEK"
     gene            complement(7174..7389)
                     /locus_tag="ROH59_004634"
     CDS             complement(7174..7389)
                     /locus_tag="ROH59_004634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807026.1"
                     /translation="MKKLRVTVEPFQGTIPFRILQRGRVLVEGSFSGKCTQLHSRTFQ
                     VNATNEELTVECTMNAAKCRMVLQPVC"
     gene            complement(7386..7478)
                     /locus_tag="ROH59_004635"
     CDS             complement(7386..7478)
                     /locus_tag="ROH59_004635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001443905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HDX4807027.1"
                     /translation="MMTMQKQLEGAQEYIRTQCTKLAFYYPEDT"
     gene            complement(7475..7660)
                     /locus_tag="ROH59_004636"
     CDS             complement(7475..7660)
                     /locus_tag="ROH59_004636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rz1 family lipoprotein"
                     /protein_id="HDX4807028.1"
                     /translation="MRELKMKLCALMLPLVVSACGSTPPAPVPCVKPPAPPAWIMQPA
                     PDWQTPLNGIISSSENG"
     gene            complement(7882..7968)
                     /locus_tag="ROH59_004637"
     CDS             complement(7882..7968)
                     /locus_tag="ROH59_004637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807029.1"
                     /translation="MSAELIRAIAFAIRIVAIAVLVWAIRWW"
     gene            complement(8523..9056)
                     /locus_tag="ROH59_004638"
     CDS             complement(8523..9056)
                     /locus_tag="ROH59_004638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HDX4807030.1"
                     /translation="MNAKIRYGLSAAVLALIAAGAPAPDILDQFLDEKEGNHTTAYRD
                     GAGIWTICRGAILVDGKPVVPGMKLSKEKCDRVNAIERDKALAWVEKNIKVPLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYRRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VFRRDQESALACWGIDR"
     gene            9162..9434
                     /locus_tag="ROH59_004639"
     CDS             9162..9434
                     /locus_tag="ROH59_004639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807031.1"
                     /translation="MDNNTISLQELLDSISRLREDVNTLTVAFSYLAFSIPREQMQST
                     LASIQFESCNPKWSQEQQDSFRRLAVLLDEKYAGKITISADSSENP"
     gene            complement(9400..9744)
                     /locus_tag="ROH59_004640"
     CDS             complement(9400..9744)
                     /locus_tag="ROH59_004640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdfR family protein"
                     /protein_id="HDX4807032.1"
                     /translation="MTQNYELIVKGIRNFENKVTVTLALRDKKRFDGEIFDLDISLDR
                     VEGAALEFYEAAARRSIRQVFLDVAAGLCEGDEQSPEKRPVILEAQDVLITYRGKLPG
                     IITGSLKSPPKW"
     gene            complement(9749..9964)
                     /locus_tag="ROH59_004641"
     CDS             complement(9749..9964)
                     /locus_tag="ROH59_004641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HDX4807033.1"
                     /translation="MYQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGS
                     LLFGLLTYLTNLYFKIREDRRKAARGE"
BASE COUNT         2282 a         3141 c         2432 g         2342 t
ORIGIN      
        1 gcatcattca ccgcctgctg cagtacatcc ggatcataat cacgaccatc acgcggtacc
       61 ggaatggccc ccacagcgtc atccaccatc gcctgcagaa ccggacgcac ctcatccacc
      121 gtcacatgct tctgtaatac cgccgacagg gaagtcagtt tctcttcaaa cgcttgtgcc
      181 tgcgaggcca tcttcccctc aaatgtgcgc tgtaaatccg ccagcactgt ggagaattct
      241 tctcccagtg cacgaataat ggacagttcc cgttccgtca ttttctcagt atcccccctg
      301 aacatcgctt tcaccgcatc atgctctgtt tcactgattg ccttattacc gtcagatgcg
      361 ccgtcaggca gctgtgatga aactgttttc ccggcagacg cgaacggatc ctcacgggca
      421 tcacgacggg acagcgcctc cagactgtag ttctgctgct gaagatacag tgcatcaccg
      481 ccggccaggg gcggcaggtt ctcccgttta cgggcctcat tgggcgtgag aagcgtattt
      541 ttcaccgcat cccccagcgt tttcatgcgc cgctcactgt ccattctcag cagcgtggtg
      601 acatcaaatt ctgtactctc gttttccccc gtttccagcg cctcatccag taacagttca
      661 atggactcaa tcagcgtctg caggcactgg gaataatact gctgctccag cgcctccacg
      721 ttgtcactgg aaggcggttg tcccacgcca atcttgtagg ccgggacacg gaacaccgaa
      781 cagacaattt cagcggtcat cttcagttgt tccaccgtct gcgcatccac aggtgaaaac
      841 gtcgtggggt tgtattttgc cccgttgctc agaatggccg ttttccccgc attttcgcct
      901 gtatacccgc tgtcccagtt gctcttcagt tttttcgcat tttcttccgt aatactgccg
      961 gggatctcaa tcaccccgga cggcctgccg ccatttctga aaaaagacgt cgaattttcc
     1021 tgaatatgat gcccctgcgt ggccgccagc ccggcggcat acaccggcgg caatcctata
     1081 agcggatgaa aaaaacagtt aaaccggtcg tggatcactt cccgggcagg caccgtcacc
     1141 gcctccgtga tcccgcagtt ccggtccggc gtgatgcggt agaacacctc gccgtcatcc
     1201 gccaccagag gttcaacccg gctccagtcc agaatacgca gttctttgat ctgcccccgg
     1261 gcattacgga ttttcagcac caccgtattg ccatgacgca gtttggcgtt cagccacagt
     1321 tcaaaaaact ggatgcggtt ctgctgggcg ttgggacgac gacagaggcg ggcaatatcc
     1381 ccccggcgcg tttccctgcg tatcccatgc gcatccgtct gcataagacg cagccgcatt
     1441 ttggcgatat cctgggatat cagcgaaata catgcaaaca ccgcatgaaa ggagaggacg
     1501 gcttcaggat cggctttcac gccctgctgc caggcgccgg aaaagggctc agccaccgcc
     1561 tgaaacaggc tggtccagcc cgcctctctt acgtcacgtc ctgatttctg gttttttcgg
     1621 gttcgccgta aaaggttcca cattcgccat gctccgcatc acgtttcttt ttctgacctg
     1681 ccggacgtcg caccgtgatg tactccgcct ttcccaggcg aaccagcacc tccgcacacg
     1741 gctgtgccac atcacggata tccccggccc gggcatcatg cgtgccctgc agatatcgga
     1801 tctttgccat aacctgttac gggaggcgca cgcctcccgt cctccttatc agactcagcc
     1861 gccggacgca ctgccgtagt tcactccggt gatcaccgcc accgccgcag tacggcgacg
     1921 acgccagttg atccagcgct ccgcacggat ggccacgctg cctgtctgga acatggaaac
     1981 cagctccacc ggggacggcg tggtactgtc gccggtcggc tcagactgca tttccagtga
     2041 tgcctcgcgg gacatatcca ctgccacgcc gccgtcatcc gccagataaa tatccggggc
     2101 attcaccagc accagctggt cacccacgta ctgggagaca atcaccggca gcccctggaa
     2161 ggagccaccc agcagggtca tgtccgggta ttccttctga cccagcgcat ttttacgcat
     2221 ggacagtgcc agggcattgg tgctggacat cagccagacc gcaccggtgg gctgcaggtt
     2281 tgctgccaca aactgtccaa acgcagcctc tgcatccgca tccgggttac cggttgatgc
     2341 cgtgcccttc acatcatggg tgatggacgc cggggagaca tctgccactg cggctttttt
     2401 cgggtccaca aagtctgtat ccagacgcgc caccaccgct tccgccagcg cattacggac
     2461 cagtgcatca gcagccggac tggaaaaacg gatcaattct tccgtcagta ccgcaatggc
     2521 cgacaccttc gcatgactga aggtgatgga ttcaaaatca aacttcgtca ggggttttgc
     2581 cttaccctca cccacccagc cggcagcacc gccggacacc tgggcgtgca cacggatatt
     2641 gaatggcacc tgacgaagtg cagggatccc gccctgacca aatcgcccga taatggtctg
     2701 cggacgcagg taatcaataa agtcctgtgc gtattcctga tattcagaca ggctgcctgc
     2761 ccactgcgga tccgtggtgg tccccgcgcc cactgccgat ttcaggacat gatgcagacg
     2821 actgtcatcc ggatactgac gacgggccac ttccagggct tcagatcgga cgcctttagc
     2881 cgcagccagc gatttggcaa agcgggcgaa gccaatcccc ttatccagtt tctgctccac
     2941 acggatcacc ggcgcagaag ccaccgcggc cacattcccg ttaccggcct gtttcaccgg
     3001 ctgcgccgtg gcggccttac cggcttccag ttcacgcagg cgcttcaggt gcgcatccac
     3061 ctgacggatt tccgctgcgg tgttgtcgta atgctcttcc tcctccacat ccagcgtgcg
     3121 cccttcctct gcggctttgg tcatgacctc ctcaagggag gctgccagcg ctgcacgctt
     3181 gttttcaaaa cttttaatct gttcgccaat attcattatg gtcttttcct tatgaaaaac
     3241 ggttgttgac tgtgccgcag cgccggcaga agatgcgatt ttcaccaccg gtttccggtt
     3301 gccggacgcg gcagaaaacg ggcggtcgta agatttaatg gtccggatgg tgcattccgc
     3361 attcgcgggc acggtgacgg cagacacctc catcagttcc cagcgcagaa aatgcagtcc
     3421 gcctccgtcc agaaaggtgt attcatgggg acggaagccc acggacagcc ccctgaccag
     3481 cccggtctta atggccgccc agacctcatc cagccgggca gccagttgcg acggcatatc
     3541 cggtacgggc ttcaccagtg ttgccgtgat ttccagccct tcgctgaccc ggcgcaccgt
     3601 acactgcccc accgggcggg aatggtcatg ctgccagaga aacgggatcg cactgccaaa
     3661 ctccgcgccc tccggctcca ggatgtcacc atcccgatcc ggagaaggcg ttgacgcaat
     3721 cccggtgatc acccgttcat cctcactgaa ggatttcacc gtcagcaggg aacaggcccg
     3781 tttaagagtc acatcagcct cctgaaaata aaaaaaccgc cggagcggtt cgtgatggtt
     3841 acagtgtgaa cagggttata tgaaaaaaac cgcatattct ttctttttcg gttccgggtt
     3901 aagggacatc agggagaccg cattgaacag cgccatcagc gggtcaattt ttccccgtcc
     3961 actggcctgt ttggtgataa gaatggcgtt acctttaggc tccacccggg cattgccgac
     4021 acaccaggcc atcaggggct ggtcaccatg caccagcacc ccttcagcca gtttgcgctc
     4081 ggtggtttta atggccccgc ccagtttcca gccctggctt atccccacca caattccgtc
     4141 ggggatcccg gcttccgcca gtgaatccag aatctgcccc acccctgacg ggtcaatacc
     4201 gatatggtcc agtaactcag cctcatgaat gcgacgcaca tattccgcca cttccgccgt
     4261 gtcatccccg acacgccgga caatggtcat atctccacag gcaacaagat cctgaaaccg
     4321 ggacgcctcg ctcttccgtc ggaccaccgc ggtttcatgc gcccaggcat ggccccagcc
     4381 cagccattcg cgggtctccc ggtcacgccc aatcacatac atccccagca gatcatccag
     4441 ccctccgccg tcaatcccca ccgtcaccac atcagcacga cgcaggatat cgtccaggct
     4501 gatacaacgg ccctgctctt cccagaaatc agcccccgcc cagcggtcag agcgcagggc
     4561 aagaccaatt tccacattgg cgtgttttga catgaacccc cggaatgtct cttcaccggc
     4621 ttcccgggct ttacggtact cccggtacag aaaggcctca tccactgaat agccgagatt
     4681 cggattgacc atggcgaggt tttccatcag caggttagtc ccgctttcca ccatttcagg
     4741 agggtgttca aatatcaccg gcagaaagtg cggatcatga attttgccgt cgcgcacatc
     4801 ccgggcgtac tgcagtttct gtctgaacac cccggcgggc ggttcattcg actgggtggt
     4861 cgtatacacc acaaaccctt ccgggcggga ggcaaggccg cctatggctt cacgtaacat
     4921 gtcctccgcc ttgcactgct tgccaaacag ccacaactca tcaatcagcg tacccacgga
     4981 cttgataccg gacaccgtat tcggatcggc tgccaccacc ttcagggtgg tgtccgtcac
     5041 tcggtgggtg atggtccgga tatgggtctg tacctggcag aggtcatcca gatcatcgtc
     5101 acgtcgtacc atatcccggg cagggttgaa ggcgttggcc gccacctcca cagtcggggc
     5161 cagaatcgtg taacccgccg cctgccgcca gttcagtaac agtgcagtca tcatgatccc
     5221 cgcggccagc gtggacttcg agtttttctt ggggataagg ataaaaactt ccttgatatg
     5281 gcgtacaccg gtctgcgcat cgtaggagcc aaacagggcc gccaccaggt caaacaccca
     5341 cggtgcacag gactccccga acgtagggct accaggtgca tccacaatcc gcagttgttt
     5401 aaaaatcgcc agggcatgtg cggcctcgtc cggataaatc ggatccggaa taatcgacag
     5461 cccctttttc aggcgctctg cccagtccgg gcaggctgtg ctccatacag gtatcatccg
     5521 ttgccctcat tatcgttatt caccaccagt cgggggggcg gtggcaccgc aaaacggtta
     5581 gccgcttttt tcgcggcatc accttttgcc gattttttcc cggtatcccc ttttttatgg
     5641 tgcgtgaact gcgccagacg ccaggccgca tccagtgcca gtttcggatc aatgcagagg
     5701 ttttccacca ggatccgccc catggctttc accggatcgg gaagaccatc ctccatatat
     5761 tcaataccag gagacatcac cgcggacggt ggcatctcca gattgttttc gtccggctgt
     5821 ggtattgcag ccgcctcacg gcgacggggt ttatcctcct gctctgattt tttctgccgg
     5881 taaacaggaa cctcatccac ctccaccgtc tcgcattgtt tacgggctat aaacgcaagc
     5941 acctcaggat cttttgccag ctgcgagcct ttaaccctgg cggtcttcgc cgaataaccg
     6001 gcggcaatgg ctgacgctgt tttgtttttc ccggacatga gcgccagcgc aaattttcgt
     6061 ttttgcgttg tcagcacagc ctcctcccgg gtccagaacg cactcagccg ggtatggttc
     6121 agcccatttt tcccggcgtc tcatgccgca aatgttaact gctgcctggt taacatttgc
     6181 tgaaaaagcc tgttaacatt ttttccgcac aacaaactga ataataaaga taaaaaccgc
     6241 aaaaatgccc gggcagccag ttaacatgtt aactgccctg aaacgggaat tttttctctg
     6301 cgtgagaggg ggcgcggtgt ccaaagcgat cgttttttac gccggatgat accccccccg
     6361 ggttgggtta cagtccgatg atgtcgtcct ctctgccact acctccggac acctccggca
     6421 gcgtcgggtc cggcatacca ctcgccgctt cacgagcaga cttttgtcga tggcattcgg
     6481 cacagagcgt ccaaagattc gtctcctcat taccaccacc gaactgaagt gcaattcggt
     6541 gatcgagttc actgtcacag aggtcaacca cacgaccaca gatacagcac tgcccggcgt
     6601 ccctcagcca gatatgacgc ttgagggaaa cacgtgcact gccactgaca cgacgctgct
     6661 cccccttcag aatattcacc cgtcgggtat tcagtgtttt gattctgctc tggagtgtac
     6721 gaagctcagc catgtaaaat ccccgtcata tggcaatcag taaaggaaat aaatatgtca
     6781 tcgaaaaacc ggacccgcag aaccacaacc cgcaatatcc gtttccccaa tcacataatt
     6841 gaacagatca acatcgccct tgagcataaa gggtccggta acttttcagc gtgggttatt
     6901 gaagcctgca ggagaaggct ggcaacagat gcaacgcatc tgcgcccggc cagcatgaca
     6961 aataacgaga aatgaacgtt cggtttcttc caccatcgca ccggacaggc gactatgagg
     7021 ggacaacgcc gcgctccgtt aacgcggtaa accccggtgt gtatcgtttt tgattatccc
     7081 cgcacactcg cgcagaggag tctccctgtc gggctgcggt ctctgttaat gcaggaatac
     7141 ggcgacaata ccgcgcatgg ataataaggt cgctcaacac actggctgta ataccatgcg
     7201 gcatttagcg gcattcatcg tacactccac ggttagctct tcattcgtgg cattcacctg
     7261 aaaggtccgg gagtgtaatt gcgtacattt accactgaac gaaccttcaa caagaacacg
     7321 accacgctgc aaaatacgga acggaattgt tccctgaaaa ggttctacgg ttacccgtaa
     7381 tttcttcatg tatcctccgg ataataaaaa gccagcttag tgcactgagt gcggatatat
     7441 tcctgcgccc cttccagctg cttctgcatt gtcatcaacc gttctctgag gatgaaataa
     7501 tcccgttcag cggtgtctgc cagtcggggg ccggttgcat tatccacgct ggaggtgccg
     7561 gtggcttcac gcacggtacc ggggcaggtg gcgttgaccc gcaggcgctt acgaccagcg
     7621 gcaacatcag cgcgcagagt ttcattttca gctctcgcat cggctaattc cttcgtgtat
     7681 ctggcatcaa gcgcagcgac atctcgctgg cgctgctgca tgtcagtaat agtggcattc
     7741 gccagtttca gctcactgac ttttttatcg cgctgcgctt tgtaggtgat ggcgttatcg
     7801 cggtaatgat tcagccccag actaagcaca ccacaggcta ccagcatgac aataatcacc
     7861 acacacagaa cacggttcat atcaccacca acggattgcc cagaccagaa cagcaatggc
     7921 cacaatacga atggcaaatg ctattgcccg aataagttca gcactcatct ttttaaagtt
     7981 cacgatttca gcgcaatgac cagttttgcc agcccataca gcatcggaga cacagcaata
     8041 ccaacagcca cccacttaat agcaaaagcc agcgctctgc tgatgtcatc agtcactgtc
     8101 accccagcag ccccgacgaa gacaacatca cccaggcgag ggacagaaaa agagcaacca
     8161 gcattagtga aaatgaaata ccgacaatca cacacaggac ctttgccggc gttatgagtt
     8221 tgtctgacat agctacccct taattgccac aattaactgg gatactaccc ataaaaaagg
     8281 gatgctccag accagcaaaa atttccagtt tggtaattga ctaatcatga gtcgcaactc
     8341 cctaatcagt ttgctaaaat caatcaaggc agcctcccat agcttactgc cataaaaaca
     8401 aaaccccgct tgctgccaac aaacggggtt tttactttta ttcacttagg ttttgccagt
     8461 tcacaggact tcgtgttatc cgcccgcgtt ggccaacctc atttttcagc aaaatattct
     8521 gcttatctgt cgattcccca gcacgccagc gcgctctcct ggtcacgacg gaatacctga
     8581 ccgtaacagt tatttgagcg aatacggcag tctctgccac cgtccttaat ccaccagcga
     8641 atcgcttcgc atgctcccct gcgatcacct gcattaattc gtctgtaaaa cgtcgacggg
     8701 aaacacttac cgggaccaat gttgtacgga cagaatgacg cgatccccgc tttctggggt
     8761 tcggtcaatg gcactttgat gtttttctcc acccatgcca gcgccttatc acgctcaatg
     8821 gcgttaaccc ggtcgcattt ttccttcgac aacttcatgc ccggaacgac aggtttgcca
     8881 tccaccagga tggcaccgcg gcagatggtc cagatacccg cgccatcacg gtatgccgtg
     8941 gtgtggttac cttccttttc atccagaaac tggtcgagaa tgtcaggcgc aggcgcacca
     9001 gcggcaatca gcgccagaac ggcagccgac aggccgtatc tgatttttgc gttcatggat
     9061 atttatcagg atttatcggt ttctgagccc tggatatgtt tatcagttcc agcctgttgc
     9121 ctcaggctgc taacaggtca atacaatcat gaggattatt tatggacaat aacaccattt
     9181 ctctacagga gttgctcgac agcatttcca ggcttcggga agacgtgaat acccttaccg
     9241 tcgccttctc atatctggca ttctcaattc caagggaaca gatgcaatca acgctggcat
     9301 caatccagtt tgaatcatgc aatcccaaat ggtctcagga acaacaagac tctttcaggc
     9361 ggcttgctgt attactggat gaaaaatatg ctggtaaaat taccatttcg gcggactctt
     9421 cagagaaccc gtaattattc ccggtagttt tcctctgtag gttatcaaca catcctgcgc
     9481 ctctaaaatt acggggcgct tttccggcga ctgctcatcc ccttcacata acccggcagc
     9541 aacatccagg aagacctgtc tgatgctcct tctggctgct gcctcataaa actccagcgc
     9601 ggcaccttca acacggtcca gcgagatgtc caggtcaaaa atttcaccgt caaagcgttt
     9661 tttgtcccgt aacgctaaag ttaccgtaac tttattctca aaattgcgga tccctttcac
     9721 aatcagttca tagttttgag tcattgaatt actctccccg tgccgcctta cgacggtcct
     9781 ctctgatttt gaaatacagg ttagtcagat atgtcagcag cccaaacagc agactcccca
     9841 gcacgcctat tgccgcccac tgagacgggg aaaccctgtc cagcaactgc aggaaccagt
     9901 agcccgttcc caccgctgac gtggtgtatg acacacctgt tgtgattttt tccatctggt
     9961 acataccccg tctcccgtta tccggaagct gacaacaata aaaaaagcca ccagttaagt
    10021 actgatggct ctgataactc atgcaggcat ctcagacgac ccactgacac taccggtgag
    10081 tttaacgata ccttccattt gactggctca ctttttatga tgatgccggt gcatttatct
    10141 ccagcaccag actttctatc tcaacgccat acgttgcatt tttggtaata tccgtca
//
LOCUS       DAPOXO010000136         9981 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPOXO010000136 DAPOXO010000000
VERSION     DAPOXO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9981
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.136"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            364..864
                     /gene="tssB"
                     /locus_tag="ROH59_004642"
     CDS             364..864
                     /gene="tssB"
                     /locus_tag="ROH59_004642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HDX4807034.1"
                     /translation="MADSFQNEVPAARVNIKLDLHTGNAKKKVELPLKLLAVGDYSNG
                     KEQRPLSERDKIDINKNNFNSVMAEFSPAVNLTVEDTLNGNGNEQNIALEFKSLKDFE
                     PEQVAKNIPQLRVLLAMRNLLRDLKSNLLDNATFRRELENILKDPTLSSELRDELAKI
                     APQENV"
     gene            923..2461
                     /gene="tssC"
                     /locus_tag="ROH59_004643"
     CDS             923..2461
                     /gene="tssC"
                     /locus_tag="ROH59_004643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HDX4807035.1"
                     /translation="MSVQQEHATSETATLTTTESGGVYQSLFDKINLTPVSSIQEIDS
                     WQNSETLADASPDERVTAAIHVLLSCLAKSGEDVVKLDKSLLDFHIDDLDQKISKQLD
                     AVMHHPEFQKVESLWRGTWFVVQRTDFRKNVRIELLDVSKEHLRQDFDDSPEIIQSGL
                     YRHTYIQEYDTPGGEPVASLISSYEFDNSPQDIALLRNISRVSAASHMPFIGSVGPKF
                     FLKNSMEEVAAIKDIGNYFDRAEYIKWKSFRDTDDSRYVGLVMPRVLGRLPYGPDTVP
                     VRSFNYVEEVKGPDHEKYLWTNASFAFAANMVKSFVNNGWCVQIRGPQAGGAVADLPI
                     HLYDLGTGNQVKIPSEVMIPETREFEFANLGFIPLSYYKNRDYACFFSANSAQKPALY
                     DTADATANSRINARLPYIFLLSRIAHYLKIIQRENIGTTKDRRVLELELNTWIRTLVT
                     EMTDPGDELQASHPLRDGKVIVEDIEDNPGFFRVRLFAVPHFQIEGMDINLSLVSQMP
                     KAKA"
     gene            2479..3816
                     /gene="tssK"
                     /locus_tag="ROH59_004644"
     CDS             2479..3816
                     /gene="tssK"
                     /locus_tag="ROH59_004644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HDX4807036.1"
                     /translation="MKIHRPLWAEGTFLSSQQFQQQARWEAFSNDSIAQLCIRHPWGI
                     ANVLFDRDALTSGKLKTQAVRLRFADGTLIDSDVSDVLPLACDLRALKNDSAIVLLAL
                     PLAHGNGGNLGQGEQTERPLRYRQEWQKVQDIYGSDSEDMAVERHALSLRFAHDNNQD
                     YITCPLARLVRDVQGNWTQDESYIPPLLAFNAHDGLVQRLDTLLLQLRAKCQRLMAMR
                     RESNQRMADFAVADVSLFWLLNALNSAEPVLSDFLRYPAVHPELVWRELARLAGALLT
                     FSLEHNVSAVPPYVHESPSIVFPPLFSLLSELLEASLPSRVIALDLASLPGNRWKADL
                     HDPRLREEADFYLSVRSSLPAHQVLHQLPLVCKIGAPDDVTLLINVALNGVPLVPLTS
                     VPAALPLRLENQYFALDMHSDAAKSMLESGCCMIYAPGTMGDLKPELFAVLRT"
     gene            3813..4478
                     /gene="tssL"
                     /locus_tag="ROH59_004645"
     CDS             3813..4478
                     /gene="tssL"
                     /locus_tag="ROH59_004645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssL, short
                     form"
                     /protein_id="HDX4807037.1"
                     /translation="MKKETDINIDALLRDTFLTVVELRQGTTVRHGMELYRHCQRQVE
                     LVRERLKDAGFSRESVEHITYAQCALLDETVLSRGGMDDGQAIWMKDPLQSHFFNTLQ
                     AGELLYERMKQVLQEPAPAQAVLTCFHRVLLLGFRGRYQDPAAPERDQLISTLNGQVA
                     PFGVLPETAVLNVPLSPRQHPLLHSPFFWLVTLTLVLAGVWWGLHYWLNVLVDELLPQ
                     SLR"
     gene            4491..6143
                     /locus_tag="ROH59_004646"
     CDS             4491..6143
                     /locus_tag="ROH59_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDX4807038.1"
                     /translation="MRNALKQTVLLWTLLLLLTTWLGFFAVSAVVKYAVVVILVAVTA
                     AVMAYWHKKKGQVVADDVWPSSLPPETYRQPVVLVCGDMSAHLFTDSPVRQVSEGLYL
                     PVSDEEQLVAQVERLLTLRPAWASQFAVAYTVMPGMYRDAAVLTGQLRRFAHSMATVR
                     RRAGVNVPWLLWSGLSGSPLPERANSPWFICTGGEVQVATSAETTMPAQWIAQSGAQE
                     RSQRLCYLLKAESLMQWLDLNVLAELNGPEAKCPPLAMTVGLVPSLPAVDNNLWQLWI
                     TARTGLTPDIADTGTDDALPFPDALLRRLPRQSGFTPLRRACVTMLGVTTVAGIAALC
                     LSATANRQLLRQVGDDLHRFYAVPAEEFITKARHLSVLKDDAVMLDGYYREGEPLRLG
                     LGLYPGERIRQPVLRAIRDWRPPEQKMDVTASLPVQTVRLDSMSLFDVGQARLKDGST
                     KVLVDALVNIRAKPGWLILVAGYTDATGDEKSNQQLSLRRAEAVRNWMLQTSDIPATC
                     FAVQGLGESQPAATNDTPQGRAVNRRVEISLVPRSDACQDVK"
     gene            6201..6692
                     /locus_tag="ROH59_004647"
     CDS             6201..6692
                     /locus_tag="ROH59_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HDX4807039.1"
                     /translation="MAIPAYLWLKDDGGADIKGSVDVQGREGSIEVVALDHDVYIPTD
                     NNTGKLTGTRTHKPFTFTKEIDASSPYLYKAVTTGQTLKTAEFKFYRINDAGQEVEYF
                     NITLDNVKLVRVAPLMHDIKDPSREKHNHLERIEFRYEKITWTYKDGNIIHSDSWNER
                     PSA"
     gene            6883..9519
                     /gene="tssH"
                     /locus_tag="ROH59_004648"
     CDS             6883..9519
                     /gene="tssH"
                     /locus_tag="ROH59_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HDX4807040.1"
                     /translation="MTGNHPAALLRRLNPYCARALDAAASLCQTRAHAEITIEHWLLK
                     LLEQGEGDITVIARRYEWDIDTLWQSLLAHLDTLPRPVRERPQLSEPLAALIRQAWLI
                     ASLEGDDPQIRSQHLLMALTEKPMLPACNDLWVLLSLSRVQLERLRPLLDAQSDECPA
                     RQPQVTEPLTSAQPGAATTDAPAKTLTGKQDDALLAVLNRFTEDVTEKARSGRIDPVF
                     GRDTEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALRITEGNVPDSLKTVHIRT
                     LDLGLLQAGAGVKGEFEQRLKNVIDAVQKSPEPVLLFIDEAHTIIGAGNQAGGADAAN
                     LLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKA
                     RYAQHHGVHMLDSAIQTAVRLSRRYLTGRQLPDKAVDLLDTAGARVRMSLDTLPEPLT
                     QLHARLAALDIEREAIEQDSVFYPETSPERLAELTDLRDELQAEAGHLEAQYQQEKAL
                     AQQIMTLRQEGTDSSELQQQLRTHQGFAPLLALDVDARAVATVVADWTGIPLSSLLRD
                     EQSDLLSMEQSLENRVVGQSPALCAIAQRLRAAKTGLTPENGPQGVFLLTGPSGTGKT
                     ETALTLADTLFGGEKSLITINLSEYQEPHTVSQLKGSPPGYVGYGQGGVLTEAVRKRP
                     YSVVLLDEVEKAHRDVMNLFYQVFDRGFMRDGEGRVIDFRNTVILMTANLGSDHIMQL
                     LEEKPDATDADLHELLYPLLRDHFQPALMARFQTVIYRPLGQEAMRTIVEMKLAQVVR
                     RLHQHYGLETEINDSLYDQLTAACLLPDTGARNIDSLLNQQILPVLSQQLLAQQAVHH
                     KPARLRLGWDEEDGIVLEFDEK"
     gene            9531..>9981
                     /locus_tag="ROH59_004649"
     CDS             9531..>9981
                     /locus_tag="ROH59_004649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX4807041.1"
                     /translation="MNVQFFDHAHHKLKIRGLKSPVDVLTFTGHEQLSSPFRYDIEFT
                     STDKAIEPESVLMQDGAFSLSAPPVQGMPVQVPLRTLHGVITGFKHLSSSQDEARYEV
                     RLEPRMALLTRSRQNAIYQNQTVPQIVEKILRERHQMRGQDFVFNLKS"
BASE COUNT         2273 a         2779 c         2827 g         2102 t
ORIGIN      
        1 aaccttttaa ttagtagaaa aattaataat tttttgtgga agcccggaca ataagtttca
       61 tgaatatctt aataggctct catactaccc aatttcttaa aagtgcaaat ttgtgaagct
      121 tatcctgtta ttattttaag tttcatgcca aattctctca ccagataatg ccgccctctc
      181 ccgaaaaata atcaagaggc caaacaatat ctaaaatgat acaactgtat ctattcccct
      241 gaaaaataca ttattcattt gtatattttc ctcatcattg ctttttattt aaatcatccg
      301 ataatcccct gaatataatt atgtcaataa ccatcagaaa aagtggatga tgaggaaaag
      361 gatatggccg acagtttcca gaatgaagtt cccgccgctc gtgtaaatat caagcttgac
      421 ctgcatacag gcaatgctaa aaagaaagtt gaactccccc tcaagcttct tgccgtaggc
      481 gattacagta acggaaaaga gcagcgtccg ctgtccgaac gggacaagat tgatatcaat
      541 aaaaacaact tcaacagcgt catggctgag ttttcgcctg cggttaattt aacagtagaa
      601 gatacgctaa acggaaacgg taatgaacaa aatatcgcgc ttgaatttaa aagcctgaag
      661 gattttgagc ccgaacaggt agcaaaaaat attccacaac ttcgtgtatt actcgctatg
      721 cgcaatttac tacgtgacct gaaatccaat ctgctggata acgcaacgtt tcgccgtgaa
      781 ctggaaaata tcctgaaaga cccgacgctc agttcagaac tgcgtgatga actggcgaaa
      841 attgcgccgc aggagaacgt ttaacccgaa cgcgtattca ggttaaaccg gagaagaaag
      901 gatcactgaa aaggaaatgc tgatgtctgt acaacaagaa catgccacct ctgaaactgc
      961 aacactcacc accactgagt ccggcggcgt ttatcagtcc ctgtttgata aaattaattt
     1021 aaccccggtc tcttccattc aggaaatcga ttcatggcaa aacagcgaaa cgctggccga
     1081 tgcctcaccc gatgagcgcg tgacggcggc tatccacgtt ctgctttcct gtctggcgaa
     1141 gtctggcgag gacgtggtta aactcgacaa aagcctgctg gattttcata tcgacgatct
     1201 ggatcagaaa atcagtaaac agcttgatgc agtcatgcac catccggaat tccagaaagt
     1261 cgagtcgctc tggcgcggca catggttcgt cgtacagcgc actgattttc gcaaaaatgt
     1321 cagaattgaa ctgctggatg tcagtaaaga acatctgcgg caggactttg atgattctcc
     1381 ggaaatcatt caaagtggtt tatatcgcca tacatacatt caggagtacg atacgccggg
     1441 tggcgaacct gtagcctcat taatatccag ctatgaattc gataacagcc cgcaggatat
     1501 tgccctgctg cgtaatattt ccagagtctc tgctgcatca catatgccct ttatcggttc
     1561 cgtcggaccg aagttcttcc ttaaaaactc gatggaagaa gtcgccgcaa ttaaagatat
     1621 cggcaactat tttgaccgcg cggaatatat caaatggaag tcgttccgcg ataccgacga
     1681 cagtcgctac gtgggattag tgatgccgcg cgtgctgggc cgtctgccct atgggccgga
     1741 cacagtgccg gtacgcagct ttaactatgt ggaagaagtc aaaggcccgg atcacgaaaa
     1801 atacctctgg acaaacgcct cgttcgcctt tgccgccaat atggtgaaga gctttgtgaa
     1861 taatggctgg tgcgtgcaga tccgtggtcc gcaggcgggt ggcgcagtgg ccgatctgcc
     1921 gatccatctt tacgatctcg gcaccggcaa tcaggtcaaa attccgtccg aagtgatgat
     1981 cccggaaacc cgcgaatttg aatttgccaa ccttggcttt attccgctct cttattataa
     2041 gaatcgcgat tacgcctgct tcttctcagc gaactctgcc cagaaaccgg cgttgtatga
     2101 taccgctgac gccaccgcca acagtcgtat taacgcccgt ttgccctata ttttcctgct
     2161 gtcccgcatt gcgcattacc tgaaaatcat ccagcgcgag aatatcggta ccaccaaaga
     2221 ccgccgcgta ctggaactgg agcttaacac ctggatccgc acactggtga cggagatgac
     2281 cgatccgggt gatgaactgc aggcgtctca cccgctgcgc gacggcaagg ttatcgtgga
     2341 agatattgag gacaatccgg gcttcttccg cgtcagactc tttgccgtgc cgcatttcca
     2401 gattgaaggg atggatatca acctgtcact ggtttcccag atgccgaaag cgaaagcctg
     2461 accgggccgt ggtgtgatat gaaaattcat cgaccactgt gggctgaggg gacattcctg
     2521 tcctctcagc agtttcagca gcaggcccgc tgggaagcgt tcagcaatga cagcattgcg
     2581 caactttgta ttcgtcatcc gtgggggatc gcgaatgtgc tctttgaccg cgatgccctg
     2641 acgtccggaa agctgaaaac gcaggctgta cgtctgcgtt ttgctgatgg cacgctgatc
     2701 gattcagacg tgagtgacgt tctgccgctc gcctgcgatc tgcgcgcgct gaagaacgac
     2761 agcgcgattg tcctgctggc gctgccgctt gcgcatggta acggcggtaa tctcggtcag
     2821 ggtgagcaga ctgaaagacc gctgcgctat cgtcaggaat ggcaaaaggt gcaggatatc
     2881 tacggcagtg acagtgaaga tatggccgtt gagcgtcatg cgctgtccct gcgctttgct
     2941 catgataaca atcaggatta catcacctgc ccactggcgc gtctggtgcg ggatgttcag
     3001 ggcaactgga cacaggatga gagctatatt ccgccgttac tggcgtttaa cgcccatgac
     3061 gggctggtac agcgtctgga cacgctgctg ttgcagctac gggcgaagtg ccagcgtctg
     3121 atggcgatgc gccgggaaag caaccagcgt atggcggact tcgctgtcgc cgatgtctcc
     3181 ctgttctggc tgcttaacgc gctgaactcc gccgagccgg tactgagtga tttcctgcgc
     3241 tacccggcgg ttcatcccga actggtctgg cgggagctgg cgaggcttgc cggtgcgctg
     3301 ctgacgtttt cccttgaaca taacgtcagc gccgttccgc cctatgtcca cgaatcgccg
     3361 tccatcgtct ttccgccact tttctccctg ctcagcgaac tgctggaagc cagcctgccg
     3421 tcacgggtga tcgcgctgga tctggcgtcc ctgccgggca accgctggaa agcagacctg
     3481 cacgatccgc gcctgcggga agaggccgac ttttacctgt ccgttcgttc ctctctgcct
     3541 gcgcatcagg tactgcacca gctaccgctg gtctgcaaaa tcggtgcgcc tgatgacgtc
     3601 acgctgctta tcaatgtggc gctgaatggt gttccactgg tgccgcttac ctcagttccg
     3661 gcagcgctgc cactgcggct ggagaaccag tattttgcgc tggatatgca cagtgacgcg
     3721 gctaaatcga tgctggagtc cgggtgctgc atgatttatg cgccgggaac aatgggcgac
     3781 ctgaaacctg aactgtttgc ggtgctgcgc acatgaaaaa agagacggat atcaatatcg
     3841 acgcgctgct gcgcgacacg tttctgacgg tggtggaact gcgtcaggga accaccgtgc
     3901 gtcacggtat ggagctgtat cgccactgcc agcggcaggt ggaactggtc cgcgaacgcc
     3961 tgaaagatgc cgggttcagc cgggagagcg tggagcacat tacttacgcg cagtgcgccc
     4021 tgctggacga aacggtcctg agccgtggcg gcatggacga cggtcaggcc atctggatga
     4081 aggatccact ccagtcgcat ttcttcaaca ctctgcaggc cggtgagctg ctgtacgagc
     4141 ggatgaagca ggtgctacag gagcccgccc ccgcgcaggc cgtgctgacc tgctttcacc
     4201 gtgtcctgct gctgggattt cgcgggcgtt atcaggatcc ggcagccccg gagcgcgacc
     4261 agcttatttc gacgctcaac gggcaggtcg cgccatttgg tgtgctgccg gaaacggcgg
     4321 tactgaacgt gccgttatcc ccccgtcagc accctttgct gcattcgcca tttttctggc
     4381 tggtgacgct cacactggta ctggccggtg tctggtgggg gctacattac tggctgaacg
     4441 tgctggtgga tgaactgctg ccgcaaagtc tgcgttaaag ggagtcgtga gtgaggaatg
     4501 cgctgaaaca gacggttttg ttatggactc tgttgttgct gctgactacc tggctgggtt
     4561 tctttgctgt atctgcggtc gtgaagtatg ccgtggtagt gattcttgtc gccgtcacag
     4621 cggcggtgat ggcgtactgg cataagaaaa agggacaggt cgtagcggac gacgtatggc
     4681 cgtcatcgct accgccggaa acctaccgac agccggtagt gctggtctgt ggcgatatgt
     4741 cggcgcacct gttcactgac agcccggtcc ggcaggtttc agaagggctg tatctgcctg
     4801 tttctgatga agaacagctt gtggcgcagg tggagcgatt actgaccctt cgcccggcgt
     4861 gggcatcgca gtttgccgtg gcgtataccg tcatgcccgg catgtaccgg gatgcggcgg
     4921 ttctgaccgg acaactgcgc cggttcgctc acagtatggc gacggtgcgt cgccgggcgg
     4981 gcgtaaacgt accctggctt ctctggagcg ggctgtccgg ctcgccgttg ccggagagag
     5041 cgaattcacc gtggtttatc tgtaccggcg gcgaagttca ggtagcaaca tccgcagaga
     5101 ccaccatgcc cgcgcagtgg attgcacaat ccggcgcaca ggaacgcagt cagcgactct
     5161 gttacctgct gaaagccgaa agcctgatgc agtggctgga tctgaatgtg ctggcggaac
     5221 tgaacggccc ggaggcgaaa tgtccaccac tggcgatgac cgttgggctg gtcccctcgt
     5281 tgcctgcggt ggataacaac ctgtggcagt tgtggatcac cgccagaacc ggcctgacgc
     5341 cggatatcgc ggacaccggc acagacgatg cgctgccatt cccggatgcc ctgttacggc
     5401 ggttgccgcg tcagtcgggc tttaccccgc tgcgacgggc ctgcgtgacc atgctgggcg
     5461 tcaccaccgt ggcgggtatc gccgcgctgt gcctgtcagc cacggcaaat cgccagttat
     5521 tacggcaggt cggtgacgat ctgcaccggt tttatgccgt cccggcggaa gaatttatca
     5581 ccaaagcccg tcacctgtcg gtgctgaaag acgatgcggt catgctcgat gggtattacc
     5641 gggaaggaga accactacgt ctcggtctgg ggttataccc cggtgaacgc atccgccagc
     5701 cggtattacg cgccattcgc gactggcgtc cgcctgagca aaaaatggac gtgacggctt
     5761 cgcttccggt tcagaccgtg cgtcttgaca gtatgtcgct gtttgacgtc ggacaggccc
     5821 gcctgaaaga cggctcgaca aaagtgctgg tggatgcgct ggtgaacatc cgggcaaaac
     5881 cgggctggct gatcctcgtg gccggatata ccgatgccac cggcgatgaa aaaagcaatc
     5941 agcagttatc gctgcggcgt gccgaagcgg tgcgcaactg gatgctgcag accagcgaca
     6001 tcccggccac ctgttttgcc gtacagggac tgggcgagag ccagcctgcg gcgaccaacg
     6061 acacgccaca gggccgggca gtcaaccggc gtgtcgaaat cagtcttgtt ccgcgttctg
     6121 acgcctgtca ggacgtgaaa taaaacatac cgccggaaga aggcggtgct tcaatcacac
     6181 taacaaggag agtaattctc atggctattc ctgcttatct ctggctgaaa gatgacggcg
     6241 gcgcggatat caaaggttcc gtggacgttc aggggcgcga aggtagcatc gaagtggtgg
     6301 cgctggatca cgatgtgtac atcccgaccg acaacaacac cggcaaactg accggtaccc
     6361 gtactcacaa gccctttacg tttaccaaag aaatcgatgc ctccagcccg tatctctaca
     6421 aagctgtgac caccggccag actctgaaaa cggcagaatt taagttttac cgcatcaacg
     6481 atgccggtca ggaagtggag tacttcaaca tcacgcttga taacgtcaag ctggtcagag
     6541 tcgctccgct tatgcacgac atcaaggatc cttccagaga gaagcataac cacctggaac
     6601 gtattgagtt ccgctacgag aaaatcacct ggacttacaa agacggcaac atcattcatt
     6661 ccgactcgtg gaatgagcgt ccttccgcct gataactgcg gcagacagga aactgtctgc
     6721 ctttttgttg tgtgctttgt ccagtgccgc aggcaccggt actgagcaaa gcatacccac
     6781 aatctggtga aacctgatgg gcctgagtga ggtaacggct atgggcggta gcgtgcctga
     6841 acgcggatcg caggaataca gaacacgata aggaaacctt ctatgaccgg aaatcacccc
     6901 gccgcgctgc tgcgtcgcct taacccatac tgtgcacggg cgctggacgc tgccgcctca
     6961 ctgtgtcaga cccgcgccca tgcggaaata accattgaac actggctgct gaaactgctg
     7021 gagcagggag aaggcgatat cacggtgatt gcccgccgct atgaatggga tatcgacacg
     7081 ctctggcagt ctctgctggc acatctggac accttacccc gcccggtccg cgaacgtcct
     7141 caactttctg aaccgctggc agcgcttatc cgacaggcgt ggctgatagc gtcactggaa
     7201 ggcgacgatc cacaaatccg cagccagcat ctgctgatgg cgctgacaga aaaaccgatg
     7261 ctgcccgcct gtaatgacct gtgggtattg ctgagcctga gccgtgtgca gcttgagcgg
     7321 ctgcgtcccc tgctggatgc gcagtcggat gaatgtccgg cacgtcagcc acaggtcacc
     7381 gaaccgctga catccgcgca acccggggcg gcaacgacgg acgcaccggc aaaaacgctg
     7441 acggggaaac aggatgacgc cctgctggcg gtgcttaacc gctttaccga agacgtgacg
     7501 gaaaaagccc gcagcgggcg aatcgacccg gtattcgggc gcgacacgga aattcgccag
     7561 atggtcgata tcctctcccg tcgccgcaaa aacaacccga ttctggtggg agaaccgggg
     7621 gtgggcaaaa ccgcgctggt ggaagggctg gcgctgcgta tcaccgaagg caacgtgccg
     7681 gacagcctga aaacggtgca tatccgcaca ctggacctcg gtctgttaca ggctggcgcg
     7741 ggcgttaaag gtgaatttga acagcggctg aaaaatgtca tcgatgcagt gcagaaatca
     7801 ccggagccgg tactgctgtt tattgatgaa gcccatacca ttatcggtgc gggtaatcag
     7861 gcaggcggcg cggatgcggc gaacctgctg aaaccggcgc tggcaagggg cgaactgcgc
     7921 accatcgcgg cgaccacgtg gagcgaatac aaacagtatt ttgagcgcga cgccgcgctg
     7981 gaacgccgct tccagatggt gaaagtcgac gagccggatg atgacaccgc ctgcctgatg
     8041 ctgcggggac tcaaggcccg ctatgcacag caccacggcg tacatatgct ggacagcgcc
     8101 attcagaccg ccgtgcgcct gtcgcgccgc tatctgaccg gacgccagtt gccggacaaa
     8161 gcggttgatt tgctggatac cgccggggca agagtccgca tgagccttga cactctgccg
     8221 gagccgttga cgcagcttca tgcgcgactg gcggcgctgg atatcgagcg ggaggcgatt
     8281 gagcaggaca gcgtgtttta tcccgaaacc agcccggagc ggctggcgga actgaccgat
     8341 ttgcgtgatg agctacaggc agaagccggg catctggaag cgcagtatca gcaggaaaag
     8401 gcactggcgc agcagattat gacgttgcgt caggaaggaa cagacagctc tgaactgcaa
     8461 cagcaactgc ggacgcatca gggctttgca ccgctgctgg cgctggatgt ggacgcccgc
     8521 gccgtcgcca cggtggtggc ggactggacc ggcatcccgc tctcttccct gctcagggac
     8581 gagcagagcg acctgctcag tatggaacag agtcttgaaa accgcgttgt cgggcaaagc
     8641 ccggcgctct gcgccatcgc acagcggctg cgggcggcta aaaccggcct cacgccggag
     8701 aacggcccac agggggtatt cctgctgacc ggccccagcg gcaccggcaa aaccgaaact
     8761 gcgctcacac tggccgacac cctgtttggt ggtgaaaaat cccttatcac cattaatctt
     8821 tcggaatacc aggaaccgca taccgtttcc cagttgaaag gctcgcctcc aggctacgtt
     8881 ggttacggtc agggtggcgt acttaccgaa gccgttcgca aacgccctta cagcgtggtg
     8941 ctgctcgacg aagtggaaaa ggcgcatcgc gacgtgatga acctgttcta tcaggtgttc
     9001 gaccggggct ttatgcgcga cggcgaaggg cgggtaatcg acttccgcaa caccgtcatt
     9061 ctgatgaccg ccaatctggg cagcgaccac atcatgcaac tgctggagga aaaaccggac
     9121 gccacggacg cagacctgca tgaactgctg tatccccttc tgcgagacca ttttcagcct
     9181 gcactgatgg cgcgttttca gacggtgatt taccgcccgc tgggacagga ggcgatgcgc
     9241 accattgtgg aaatgaaact ggcgcaggtg gtccgccgtc ttcaccagca ctacggactg
     9301 gaaacggaaa tcaacgacag cctgtatgac cagcttaccg ccgcctgcct gctgccggat
     9361 accggggcgc gcaatatcga cagcctcctg aaccagcaaa tcctgccggt cttaagccag
     9421 cagttgctgg cacagcaggc cgtgcatcat aagcctgccc gactgcggct tggctgggat
     9481 gaggaggacg ggattgtact ggaatttgat gagaaataat ggaggctctt atgaacgtac
     9541 agttcttcga ccacgcacac cacaagctca aaattcgcgg cctgaaaagc ccggtggacg
     9601 tgctgacttt tacaggccac gaacagctca gctcaccctt ccgctacgac attgagttta
     9661 ccagtaccga taaagccatc gagccggagt cggtactgat gcaggacggc gcattcagcc
     9721 tgagcgcccc gccggtacag gggatgccgg tgcaggtccc cctgcgcacc ctgcacggcg
     9781 tcattaccgg ctttaaacac ctctcctcgt cacaggacga agcccgttac gaagtgcgcc
     9841 ttgaaccccg tatggcgctg cttacccgca gccgccagaa cgccatctac cagaaccaga
     9901 cggtgccgca aatcgtcgaa aaaatcctgc gcgagcggca ccagatgcgc ggtcaggact
     9961 tcgtgtttaa cctcaaaagc g
//
LOCUS       DAPOXO010000137         9919 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPOXO010000137 DAPOXO010000000
VERSION     DAPOXO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9919
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.137"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            218..1312
                     /gene="ddlA"
                     /locus_tag="ROH59_004650"
     CDS             218..1312
                     /gene="ddlA"
                     /locus_tag="ROH59_004650"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDX4807042.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYTIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNNNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            complement(1336..1548)
                     /locus_tag="ROH59_004651"
     CDS             complement(1336..1548)
                     /locus_tag="ROH59_004651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HDX4807043.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            1808..2116
                     /locus_tag="ROH59_004652"
     CDS             1808..2116
                     /locus_tag="ROH59_004652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HDX4807044.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            complement(2175..3269)
                     /gene="yaiW"
                     /locus_tag="ROH59_004653"
     CDS             complement(2175..3269)
                     /gene="yaiW"
                     /locus_tag="ROH59_004653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HDX4807045.1"
                     /translation="MSRVNPLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAGKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(3282..4502)
                     /gene="sbmA"
                     /locus_tag="ROH59_004654"
     CDS             complement(3282..4502)
                     /gene="sbmA"
                     /locus_tag="ROH59_004654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HDX4807046.1"
                     /translation="MFKSFFPKPGMFFLSAFVWALIAVIFWQVGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIVGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            4854..6011
                     /gene="ampH"
                     /locus_tag="ROH59_004655"
     CDS             4854..6011
                     /gene="ampH"
                     /locus_tag="ROH59_004655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HDX4807047.1"
                     /translation="MKRSLLFSAVLYSASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            complement(6012..6635)
                     /gene="iprA"
                     /locus_tag="ROH59_004656"
     CDS             complement(6012..6635)
                     /gene="iprA"
                     /locus_tag="ROH59_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HDX4807048.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNSEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     gene            complement(6721..9708)
                     /locus_tag="ROH59_004657"
     CDS             complement(6721..9708)
                     /locus_tag="ROH59_004657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000556401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX4807049.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANAANYDTWGYHDNTTTDLV
                     WPYDTDNDGIADAGGMDPMGSDGNYVTYNGFVYYNNANGDFDTVFKGDTVNGTISTYY
                     LNHDYASGSVNQLDISNSVIHGSITSELPFGYYSITPAEVNAKGEVVTPQTYSGYNFY
                     NGITTDLDYNWYDGDVFTLNVSNSTIDDDYEALYFTDTYLDGDKSKSTNETFYTALGV
                     AVNLDVESNINITNNSRVAGIALSEGNTSNTTYTSEYHQWDNNINVSNSTVTSGSQTP
                     LEESNGFFGKSAEPSDYAGNGGENDVALSFSDNAGSNYSMKNNVNFDHSTLLGDVEFT
                     SHWNNDGVFFYSTGHDSNGDGVLDTNGGWVDDAQNVDELNITLNNGSKWVGSANMSAE
                     VIAPADMYDVAPNSLTPGATIEANDWGRIIDNKVFQSGVFNVALNNGSEWNTVNSSVI
                     DTLAVNNGSQVNVTDSSLVSDTIGLTNGSSLNIGEDGLVATDHLTVDSYSTVNLTEST
                     GWNNYSNLYANTITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSGVFD
                     INSSDYVLNADLVNDRTWDTSKSNYGYGIVAMNSDGHLTINGNGDVDNGTELDNSSVD
                     NVVAATGNYKVRIDNATGAGAIADYKDKEIIYVNDKNSNATFSAANKADLGAYTYQAE
                     QRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVS
                     YFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVD
                     QDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKA
                     GYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNNMKVDGQSYDSMRYELGVDAGYTFTY
                     SEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTD
                     ANYLGGGDVDQDWSANVGVKYTW"
BASE COUNT         2587 a         2459 c         2313 g         2560 t
ORIGIN      
        1 aaaaactcac cacatggtca tttaagccag gaataaatta gcttcccgtt catcattttt
       61 gtgatcttgc acacatcttt gagataacgc actttcttca ccagtacgtt gctcgctttg
      121 tcagcagaag attgcaacat tctgtcagaa ggccgcgaat cccccgtttt gtcgtggtaa
      181 tgtatgcact ttgtgttaga cgggataggt ttttaagatg gaaaaactgc gggtaggaat
      241 cgtttttggt ggtaaatcag cggaacatga agtgtctctg caatcggcaa aaaacattgt
      301 cgatgccatt gataaaagtc gcttcgatgt tgtgctgctg ggcattgata aacaagggca
      361 atggcacgtc agcgatgcca gcaattatct gctaaatgca gacgatcctg cccatattgc
      421 gttgcgtcct tcggcgacca gccttgcgca ggtgccaggt aaacatgagc atcagcttat
      481 cgacgcacaa aacggtcagc cgttgccgac ggtggatgtc attttcccga ttgtccacgg
      541 tacgctgggc gaagatggtt ccttgcaggg aatgctgcgg gtcgccaatt taccgtttgt
      601 aggttctgat gttctggctt cagcggcctg tatggataaa gatgtcacca aacgtctgct
      661 gcgcgatgcc gggctgaaca ttgcgccatt tattaccctg acgcgcgcta atcgtcacaa
      721 catcagtttt gccgaagtgg agtctaaact ggggttaccg ctgtttgtaa aaccggctaa
      781 tcagggctct tctgttggtg tcagcaaagt aaccagtgaa gaacagtaca caattgccgt
      841 cgatctggcg ttcgagttcg atcataaagt gatcgttgag caagggatca aaggtcgtga
      901 aatcgaatgc gcagttcttg gcaacaataa cccgcaagca agcacctgtg gcgagatcgt
      961 actcaccagc gatttctatg cctacgacac caagtacatt gacgaagatg gcgcgaaagt
     1021 ggtagttccg gcagccattg cgccagaaat caacgataag atccgggcga ttgccgttca
     1081 ggcttatcag acgttgggat gcgcaggcat ggcgcgtgta gacgtgtttt taaccccaga
     1141 gaacgaagtg gtgatcaacg agatcaacac cctgcctggc ttcaccaaca tcagtatgta
     1201 tccgaagctg tggcaagcca gcggtctggg ttacaccgac ctgatcacgc gtttgattga
     1261 gctggcgctg gagcgtcacg ctgcggataa cgcactgaaa accacaatgt aatattcaaa
     1321 cgcccggtaa tattcttatt gggcgttttc agtttcttca tcgcgacgac gaataatcaa
     1381 tcccgccagc cagaaactaa tcacccacgt caccagaccg acggcatagg tctgccaacc
     1441 ttttgcttca aatcccagta accccaccac gccattaaga atgaatataa ggccaatggc
     1501 gaacgcatag tagtgccagt cacggcggat ttttacaggc agattcatgg cagctccgtt
     1561 aacgaaaaac aacatctttt catattctgt aacaactgtc tgtggtgtag acaacacttt
     1621 cgcaattgtt aataaattta acttaaggtt gctattttgt gactcgcaac gaagattcac
     1681 gcttcgggaa tattcccaac atcaatttac catgattctg atattgacaa tctaaatgac
     1741 ctgtcagact tgccataagc cgctggtatc acaccagaag agaagcagat gacttccgga
     1801 ggtttttatg gctgatttca ccctgtcaaa atcgctgttt agcggaaaat atcgcaatgc
     1861 ctcttcaacg cctggcaata ttgcctatgc gttgtttgtg ctgttttgct tttgggctgg
     1921 ggcacaattg ctgaacctgc tagtgcatgc gcccggcgtc tatgagcgtt taatgcaggt
     1981 ccaggaaaca ggtcgcccac gggtggaaat tggtttaggt gtcggcacca tttttgggct
     2041 gatcccgttt ttagtaggct gcctcatttt tgcagtagtg gcgctatggc tgcactggcg
     2101 acatcgccgc cagtaagatt tacgttgcca gatgcggcct aaaacgcctt atctggcgtg
     2161 acattcctgt ttgatcactg tttcatacaa cgcgcccgcc gttcgtctac gcgcttcgca
     2221 aaccaggccg tagtcagatt gcgggtgatt ttcgggcttt ccagttgaat gccaggcaac
     2281 atttcgcggg gtagtgattt accggttttc gcttcggcaa gttgataaac tttcttgtac
     2341 agcgccgtct cctcaaaaga gaagctgtcc cctttctcta actgacggcg aatttcgctg
     2401 tcactcatcc ccagttttcc cgccagtttg cgcgttgcca gttcggtttt cccgggctct
     2461 ttactgtcgt aacgaattaa atcaccgtcc agtgccagct tcacgccgct ggccttactg
     2521 accgcgttct gaaacgcggc attacggctg gcgtaccagc cagcgttaaa atcagcaaaa
     2581 cggtatatcg gcgcgctata gctggcggga taattcagta aatggtaagt accaaaccac
     2641 aacccgccgc ggcgactgaa gacttcctga cggactgtac cgtccatttt ccacggatac
     2701 cctttggtat gctgttcggc aaaagcaata ctgacctgca tcggcccacc ggtgcgcacc
     2761 ggattgagcg aaccaaacag cgtctgcccc attggcacca tgctgatcag atcgtcaaaa
     2821 atcgcgctca attgcttttc tgtacgcacc gaatctaacc gttcgctata gcttttgccg
     2881 tttggcgatt tgatttttag cgcggtatgc accagaaaag caggaatgtg catccgttca
     2941 gcacgacggt caatctcttg ccaggcgatc ttgcttaagc ccggaacggc cggatctgcc
     3001 tgataatttg actcctgctg cgccaccgcc agcaccgagc agacgttttc cagcgtcggt
     3061 gccagcccct gactttcaaa ggtggtggcg agatctttcg cccaggcatc gcggtctttc
     3121 acgctcgcag gcatcttctg ccgcacgacg ctcgccacat ctatcgcttt ttcgcccttt
     3181 ttcaacggtt gcggagcctg actactacac cccgctaaaa ccagaaccgc caacaatgac
     3241 agcgaagata gaggattgac gcgcgacatt acttctcctt tttagctcaa ggtatgggtt
     3301 acttcctgaa ttttgtcacc atccagctca tgttcaaagc tgcgcagacg tttgtagata
     3361 gacatcaact caaccagtgt ggtccatgag ttaatcaggt actggaaagc accgcgaacc
     3421 tgaccaaaaa cgttagtaat ctgcgtcatc aggccgagtg taatcgtacc ggcaacaatt
     3481 gacggaaaca gcaagaacaa accgaaaacg ttatcgacct gcaaatagag aatgcgggcg
     3541 atattgaaat acatatagtg aaaatagagg cggaaatagt ttttccgtac ggcgctaaaa
     3601 agctcgcgta ccgtaggcgg cgtcgcgcgc gtggcatcgt cttcaccata aaccagttct
     3661 ttacggtagg cagcctctac acgctggttt ttaaactcca gccccggcag tttgatccct
     3721 accactgcca gtaatccggt ccccatcagc gaccagacga tagcggcaat caccagacca
     3781 tacggaatgt gcccgacaat cggcagctcc ggcacatgtg cggagagcgt taccagcacc
     3841 ggcaggaagg cgatcaacgt catgatagcg ttgataaagc tgacgcccat attctccagc
     3901 gttgaagcaa aacgcatggt gtcttcctgc acacgctgcg cggccccttc gatatgacgc
     3961 agttgttgcc agttcgccat gtaatattcg ttcatcgccg tacgccagcg gaacacgtag
     4021 tgactgacaa agaagttgtt cagcacactg atcaccaccg cgatcagcgc aatccccaga
     4081 aagacgccca cttcgcggta aaattgttcg atggtgactt tatgcggcga acttagcgcc
     4141 gtttgaatca gatcatagaa cggcgcatac caggcgttga cggcaacccc gacttccacc
     4201 aaaaaccagg tgacgaagat aatcagcgca gtaccgagta ttgaccagta ttgccaacgg
     4261 tgcgggctat agataaacca gaacaatgca aaaagtccta cgcaaacaat gtagtaagcg
     4321 taaaaaatca ggaaatccaa cgaccagaaa cgcgcggcgc taatcgggat ctgcccggaa
     4381 gcgccggtga tacgcgccac ccaatcaccc ccaccgactt gccagaagat aacggcaatc
     4441 aatgcccaaa caaaggccga gagaaaaaac attcccggct ttgggaaaaa agacttaaac
     4501 atatgcactc ctgctaactt cttatcgttt taacaactgc tgtgtattaa ccgcatgacc
     4561 gctacaaagc gtcagccaaa tgaaaccgcc cattgtgacc catagcaagg cgcttagttc
     4621 gccagcctga ccataagaat tgtttcgacg ggtttcacaa accaaagatt gtttacataa
     4681 gcggattaac acgcgcagga tcacaaatgc aggcattggt gagcaggaaa aagatcgtgt
     4741 ttacgcgccg ttacgttttt aacactatta ttgcactaat tcgccctttg caatccatca
     4801 atgagtagta taaatacgct cagttacctt cattcaatct atggacacca ccgttgaaac
     4861 gtagtctgct tttttctgcc gtgctgtatt cggcgtcatt gacctccgtc catgcggctc
     4921 agccgatcac tgaaccggag tttgcctctg atattgtcga tcgttatgcc gatcatattt
     4981 tttacggcag cggtgccacg gggatggcgc tggttgttat cgacggtaac cagcgcgtct
     5041 ttcgcagtta tggcgaaacg cgacctggta ataacgttcg cccgcagctg gattccgtca
     5101 tacgtattgc ttccctcacc aagttaatga ccagtgagat gctggtaaaa ttgctcgacc
     5161 aggggaccgt gaagttaaac gatccgctaa gtaaatatgc tccgccaggc gcacgcgtac
     5221 cgacctacaa tgggacgccc attacgctgg tgaatctggc aacccatacc agcgccctgc
     5281 cccgtgaaca gcccggtggc gcggcacatc gtccggtatt tgtctggcca acgcgcgagc
     5341 aacgctggaa atacctttcc actgccaaac taaaagccgc gccgggcagc caggccgcgt
     5401 actccaacct cgcattcgat ctgctggcag atgcactggc gaatgcgtcc ggcaagcctt
     5461 atacccagtt gtttgaagag cagattaccc gtccgttggg gatgaaagac accacctaca
     5521 ccccctcacc ggatcagtgc cgccgtttaa tggttgctga gcgcggtgcc agtccgtgca
     5581 ataacacgct ggcggcaatt ggcagcggcg gcgtctattc cacgccaggc gatatgatgc
     5641 gctggatgca gcagtatttg tcatctgatt tttatcaacg cagtaaccag gctgatcgca
     5701 tgcagacgtt gatttatcag cgcgcgcagt ttacaaaagt gattggcatg gatgtccccg
     5761 gcaaagcgga tgcgcttggt ttaggctggg tatatatggc cccgaaagag ggtcgtccgg
     5821 ggattattca gaagacaggt ggtggtggcg gtttcattac ctatatggcg atgatcccgc
     5881 agaagaatat tggtgcgttt gtggtggtca ctcgttcgcc gttgacgcgc tttaaaaata
     5941 tgagcgatgg catcaatgac ctggtgaccg agctaagcgg gaataaaccg ttggttatcc
     6001 ccgcatcctg attaatactc tgaaggcaaa cggttgatag cgaccagttt gcctttattc
     6061 atttcgatat agccgccttt acgcaaagca gcgagaactt ccgcaacgac agaacgcgat
     6121 atacgtgtac gttgatggat ataattcatc acgccaatac gtgatcgcaa ttcttcattc
     6181 cagtcaatca ttgataataa cgtcgcgcgg atttgttcgt aggaattatg cccaatgagc
     6241 tgaacgtcgc gtaattccag aattctattt tgccaggcta accagtaaaa agcgtctcgc
     6301 cagagttgat tttgttcaat aagagtaatg gtttgtttgg ctggcaaatg atatcccgta
     6361 cagtttcctt ctgatattaa tttgtatggt atatcgtttt tcattaaacc atcagccagc
     6421 cccataatat aaggagcctg tgtaataccg ataagtacgt tttcttctct acgcagagag
     6481 ataacacctt ctaaaataac gaaagtatct tcgctattga catcactgga aaatataact
     6541 tgcttttcat tattaaactc gaagcgcgta ccgtatctgg acaaacattt atcgagctta
     6601 ccaaattcct gaagaggttt aactacagat aacatttgcg cgtcctttgc agtaatgccc
     6661 gtcaaatcct tgacgggcat tatttagatt aaattaccta tttcttcgga gtgaagaata
     6721 ttaccaggta tatttaacac ccacattcgc ggaccagtct tgatctacgt caccaccacc
     6781 gaggtagtta gcatcggtat aggcgctgaa gttcttggtg aagctgaact gagtacccag
     6841 accaacacgt accgcagacc cttcagtacc gttatcgatg gaatcaccgt tcacatcgtt
     6901 atcgttgtta gagtcgtcgt agacgtaagc cagtttgaag tacggagtca gagcctggtc
     6961 ttcgctgtag gtgaaggtat aacctgcatc tacacccagt tcataacgca tgctgtcgta
     7021 agactgacca tcaactttca tgttgttgct cagctggtaa tcatcaccag actggaacag
     7081 accagaaacg ctgccgtaag gagttacgta acctgcatca cccagtttga agtcgtaacc
     7141 ggctttcaaa ccaaagcccc aagcgtcgga gttggtgctg ccgtcaacgt aagtaccgtt
     7201 gctcatggtt gcagacaggt cgttgttgaa gtgagagtag ctcaagctac cgtcaacaaa
     7261 gacgttgttc gcgaagtgag cagaagagta gatgtaggca gtctggctgt cttgatccac
     7321 ctgaccagaa cggtcattca tatcaccttt agcgaagcct gcagccgcac cgacgatcca
     7381 cttagcgttg ttaccgtcaa ttttggtatc aacaccgacc atgatgccgt taacatcctg
     7441 atcatagttg atggtgccgt tgtcgccgtt gaagttacca ccgaagtagc ttacccatgc
     7501 gccgccgtta tcagccagac catgacgaga gttggtcaga cgagtaccaa cggtgtcttg
     7561 ttccaggttc cagatattgg tgttcgcaga cgggatgctc agcgccatgt tagcgtagtc
     7621 ggtcagctcc atctgttgca gaacaacggt gttaccacgc tgctcagcct gataggtgta
     7681 tgcacccagg tcagctttgt tagcagcaga gaaagtcgcg ttgctgtttt tgtcgttgac
     7741 gtagataatt tctttatctt tgtaatcagc gattgcgcca gcgccagttg cgttgtcgat
     7801 acgaactttg tagttaccgg ttgcagcaac aacgttgtct acagaactgt tatccagttc
     7861 agtaccgttg tctacgtcgc cgttgccatt gatagtcagg tgaccatcag agttcatagc
     7921 aacaataccg taaccgtagt tagacttgga agtatcccac gtacggtcgt tcaccaaatc
     7981 cgcgttcaga acgtaatcgc tgctgttgat gtcgaacaca ccagaaacta cgttgccgtt
     8041 atggtcagcg atgttgccgc tagtcagttc cagtttgtca gtacggaaag cttcagtatc
     8101 aaactgatca acgttcacat ccagtacacc accgttagtt acggtgatgg tattggcata
     8161 caggttagaa tagttattcc agccagtaga ttcggttaaa ttaacggtac tgtagctatc
     8221 aacagtcagg tggtctgtag caaccaaacc atcttcacca atattcagtg aggagccgtt
     8281 ggttaaacca atggtatctg agaccagaga ggaatcagta acatttacct gagagccatt
     8341 atttacagct aatgtatcaa ttactgaact attaacggta ttccattctg aaccattgtt
     8401 cagtgctacg ttaaatacgc cgctctggaa taccttgttg tcaataatac gaccccaatc
     8461 gttagcttcg atagtggcac caggggtcag gctgttcggc gcaacatcat acatatctgc
     8521 cggagcaatt acttcagcac tcatgtttgc tgagccaacc cacttactac cgttgttcag
     8581 agtaatgttc agttcatcaa cgttctgagc atcatctacc caaccaccgt tggtatcaag
     8641 gacaccgtca ccattgctgt catggccggt tgaatagaag aatacgccat cgttattcca
     8701 gtggcttgtg aactcgacat cacccaacag ggttgaatgg tcaaagttta cattgttttt
     8761 catggaataa tttgagccag cattgtcaga gaatgacaga gctacgtcat tttcgccacc
     8821 attaccagcg taatcacttg gttcagcaga tttaccgaag aagccattgc tttcttccag
     8881 cggagtctgt gaccctgaag ttacagtgga gttagacaca ttaatgttgt tgtcccactg
     8941 atgatattcg ctagtataag tcgtgttgct tgtattgcct tcagacagcg caataccagc
     9001 tacacgggag ttgttagtaa tattgatatt gctttcaaca tcaagattta ctgcaacacc
     9061 cagagcggta tagaacgttt cattggttga cttagattta tcaccatcaa gatatgtgtc
     9121 agtgaagtaa agagcttcat agtcatcatc aatggtggaa ttggatacgt tcagagtgaa
     9181 tacgtcacca tcgtaccaat tgtagtcaag gtcagtagtg attccgttat agaaattata
     9241 gccactatag gtctgtggag ttacaacttc acctttagca ttaacttctg caggagtaat
     9301 gctgtaataa ccaaatggca gttcagaagt gattgaccca tgaattactg aattgctgat
     9361 atctaactgg ttaacagaac cgctagcgta atcatgattc aagtaataag tagaaatggt
     9421 accgttaaca gtatcgcctt taaagacggt gtcgaaatca ccattggcat tgttatagta
     9481 aacaaaacca ttgtaagtta cgtagttacc gtctgaaccc atcgggtcca tgccgccagc
     9541 atcggcaatt ccatcattgt cagtgtcata cggccaaact aaatcggtcg tggtgttgtc
     9601 atgatacccc caggtatcat agtttgctgc attagcctga gaggtgatag ccagagtgca
     9661 agccaatgct aattgtgata ctacaagttt ctttttccag gagtgcattt gtcatccctc
     9721 ctcagggacg taataagttg atccatcaat tatcaatgca tagaaaacat attatgtttc
     9781 gcgtttacga ttatgcggcg ttatagagga atggttcaat tattctttcc cctaagtccg
     9841 attgcggaca tatataaagc acgtgaacac acacacagaa ataaataaca aaaacacaat
     9901 atttcaatac gttaatgaa
//
LOCUS       DAPOXO010000138         9862 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPOXO010000138 DAPOXO010000000
VERSION     DAPOXO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9862
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.138"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..125)
                     /locus_tag="ROH59_004658"
     CDS             complement(<1..125)
                     /locus_tag="ROH59_004658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX4807050.1"
                     /translation="MEIREGHNKFYINDEQGKQIAEIVFVPTGENLAIIEHTDVD"
     gene            complement(137..367)
                     /locus_tag="ROH59_004659"
     CDS             complement(137..367)
                     /locus_tag="ROH59_004659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDX4807051.1"
                     /translation="MDQALLDGGYRCYTGENIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVTTVVKVIDTCPSGALKYRHK"
     gene            548..2179
                     /gene="dcuS"
                     /locus_tag="ROH59_004660"
     CDS             548..2179
                     /gene="dcuS"
                     /locus_tag="ROH59_004660"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HDX4807052.1"
                     /translation="MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAVARTLADSPEIRQGLQKKAQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            2176..2895
                     /gene="dcuR"
                     /locus_tag="ROH59_004661"
     CDS             2176..2895
                     /gene="dcuR"
                     /locus_tag="ROH59_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HDX4807053.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            3466..4806
                     /gene="dcuB"
                     /locus_tag="ROH59_004662"
     CDS             3466..4806
                     /gene="dcuB"
                     /locus_tag="ROH59_004662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HDX4807054.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     RTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            4884..6530
                     /gene="fumB"
                     /locus_tag="ROH59_004663"
     CDS             4884..6530
                     /gene="fumB"
                     /locus_tag="ROH59_004663"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDX4807055.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDIQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            6653..7303
                     /locus_tag="ROH59_004664"
     CDS             6653..7303
                     /locus_tag="ROH59_004664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HDX4807056.1"
                     /translation="MTRTLKPLILNTGALALTLILIYTGISAHDKLTWLMEVTPVIIV
                     VPLLLATAKRYPLTPLLYTLIFFHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWLAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITRAPEAITP"
     gene            complement(7300..8655)
                     /gene="melA"
                     /locus_tag="ROH59_004665"
     CDS             complement(7300..8655)
                     /gene="melA"
                     /locus_tag="ROH59_004665"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDX4807057.1"
                     /translation="MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALQDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEDYKNASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKAGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            8938..9846
                     /gene="melR"
                     /locus_tag="ROH59_004666"
     CDS             8938..9846
                     /gene="melR"
                     /locus_tag="ROH59_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HDX4807058.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAILNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQTFPG"
BASE COUNT         2488 a         2577 c         2400 g         2397 t
ORIGIN      
        1 tcatcgacat cggtatgttc gataatcgct aaattctctc cggtcggcac aaagacaatt
       61 tcagcgattt gcttgccctg ttcgtcatta atgtaaaatt tattgtggcc ttcgcgtatt
      121 tccattttac cctcgcttat ttatgacggt atttcagcgc gccgcttggg cacgtatcaa
      181 tcactttcac cacagtggtg acgtcgactt catccggcat gatccacggc tttcgtttga
      241 gattaaataa cttgccgttg ccacgtacgc aattgccaga atgctgacat atcgcagtgt
      301 taaaatagac atcgatattt tcgccggtat aacagcgata acccccgtcc agtagcgcct
      361 gatccatgac cttccctctc tcatcagtat ggttttcact ataagcatag ccccggaatc
      421 ttcatacagc actggcagtt tccgttgcca gagtctcttc ccctatatag ccaatcattc
      481 ttactccctt tgaattaccc gcctcatcag agataatgct taagaaattt gtcacacaag
      541 gaagctgatg agacattcat tgccctaccg tatgttacgc aaacgtccga tgaaattgag
      601 taccacagtg atcttaatgg tcagcgcggt actgttctcg gtgctattgg tggtgcatct
      661 gatttacttc tcgcaaatca gtgatatgac gcgagacggg ctagctaaca aggcactggc
      721 agtagcgcgt accctcgccg actcgccgga aatccgtcag ggcttgcaga aaaaagcgca
      781 ggagagtgga atccaggcca tcgcggaagc cgtgcgcaaa cgcaacgatc tgctgtttat
      841 tgtcgttacc gatatgcaaa gtcttcgcta ctcgcatcct gaagcccagc gtattggtca
      901 gccatttaaa ggtgatgaca tccttaaagc gctgaatggc gaagaaaatg tcgctatcaa
      961 tcgcggtttt ctggcgcagg ctttacgcgt atttaccccc atctacgatg aaaatcataa
     1021 acaaattggc gtagtggcga tcggccttga gttaagccgc gtgacccaac agatcaatga
     1081 cagtcgctgg agcattatct ggtcggtact atttggcatg ctggtcggac tgatcggcac
     1141 atgcattctg gttaaagtac tgaaaaaaat ccttttcggc ctggaaccct acgaaatctc
     1201 cacactgttt gagcaacgcc aggccatgtt gcagtccatc aaagaaggcg tcgttgccgt
     1261 ggacgatcgc ggcgaggtca ccctgatcaa cgatgccgca caagaattgc tgaattaccg
     1321 taagtcgcag gacgatgaga aactgtcgac gctaagccac tcgtggtcac aagtggtaga
     1381 tgtctcggaa gtgttacgcg acggaacccc acgccgcgac gaagagatta cgattaaaga
     1441 ccgactatta ctgatcaaca ccgttccggt gcgcagtaat ggcgttatca tcggtgccat
     1501 ttcaaccttc agggacaaaa ctgaagtacg taaactgatg cagcgactcg acggtctggt
     1561 caactatgct gacgcacttc gtgaacgatc ccacgaattt atgaataaat tgcatgtgat
     1621 tctcggatta ttgcatctga agagttataa gcagttggaa gattacattc tcaaaacagc
     1681 caataactat caggaagaga ttggctctct gctgggtaag atcaaatctc cggttatcgc
     1741 tggtttttta atcagcaaga ttaaccgcgc gaccgattta ggccatacgc tgattttaaa
     1801 cagtgaaagc cagctgccag acagcggtag tgaggatcag gtcgcgacgc tgattaccac
     1861 gttgggaaat ctgatagaaa acgcgctgga ggcattagga ccggaacccg gtggcgaaat
     1921 tagcgtaaca ttgcactacc gtcacggctg gctgcactgc gaagttaacg atgatggacc
     1981 ggggatcgca cccgacaaaa tcgatcacat ttttgacaaa ggtgtctcga caaaaggaag
     2041 cgagcgaggc gtcggtttag cacttgtcaa acaacaggta gaaaatctcg gcggcagcat
     2101 cgccgtggaa tcggaacccg ggattttcac acaatttttt gtccagatac cctgggacgg
     2161 ggagaggtcg aacagatgat caatgtatta attatcgatg acgacgcaat ggtcgcggag
     2221 ctgaatcgcc gatacgtggc acaaatcccg ggctttcaat gctgtggaac ggcttcgacg
     2281 ctggagaaag ccaaagagat tatcttcaat agcgatacgc ctatcgacct gatattgcta
     2341 gatatctata tgcaaaaaga gaacgggctc gatttactgc ctgtcctgca taacgcgcgt
     2401 tgcaaaagtg atgtgattgt catctcctcc gctgccgatg cagcaaccat caaagattcg
     2461 ctgcattacg gtgttgtgga ttacctgatc aaacccttcc aggcttcccg ctttgaagag
     2521 gcgctcaccg gctggcggca aaagaaaatg gcgctggaaa aacatcagta ttatgaccag
     2581 gccgagcttg atcagctaat ccacggcagc agctccaacg agcaggatcc tcgtcgcttg
     2641 ccaaaaggct taacgccgca gacgttacgc acgctgtgcc agtggattga cgcgcatcag
     2701 gactatgagt tttcaaccga cgagctggct aacgaggtta acatctcgcg tgtttcctgc
     2761 cgtaaatacc ttatctggct ggtcaactgc cacatcttgt tcaccagtat ccattatggc
     2821 gtcacggggc gtccggttta ccgttaccgt attcaggcag aacactactc actactgaaa
     2881 caatattgcc aataacggat cgctggttat ctgtaagtaa taattattac cgtaatgcaa
     2941 aatacccctg gcacaagtta catcgttcat cagtaaaact tgtgccagat caaatataat
     3001 tatccctcca tcatcgctaa aaattaatat ctcttcagat gaacggtgtt tttaatttca
     3061 aaacgctaac aaaagttaat taactattat gtcacccaca ttatgtgtat ttttacccac
     3121 aaatgggtag atcagattaa tctataaacc taataatacc tgccctgaga acaaaaaaca
     3181 gaccgataaa tatcaataag ataacagcaa acaaaacatt aacatctgcg ctgtacaaac
     3241 tataaaccca tcgccagaga gtctttctct ctgaaaaagc cgcttatcac agtgcataaa
     3301 tttgccgctg ctttaatcag ccaatattca ctgtgaggta tttgctcaag ccggtaacga
     3361 ccaaacggat atttagtcag gctctgaaaa cagttcatac aaaacagaac gtgactgtga
     3421 tctattcagc aaaaatttaa ataggattat cgcgagggtt cacacatgtt atttactatc
     3481 caacttatca taatactgat atgtctgttt tatggtgcca gaaagggtgg tatcgcgctg
     3541 ggtttattag gcggtatcgg tctggtcatt ctggtcttcg tcttccacct tcagccaggt
     3601 aaaccaccgg ttgatgtcat gctggttatc attgcggtgg tggcggcatc ggcgaccttg
     3661 caagcttcgg gcggtcttga tgtcatgctg caaattgccg agaagctgct gcgtcgcaac
     3721 ccgaaatatg tctcaattgt cgcgccgttt gtgacctgta cgctgaccat tctttgcggt
     3781 acgggtcatg tggtttacac cattctgccg atcatctacg acgttgctat taagaacaac
     3841 atccgtccgg aacgtccgat ggcggcaagt tctatcggtg cacagatggg gattatcgcc
     3901 agtccggtgt cggttgcggt cgtatctctg gttgcgatgc tgggtaatgt cacctttgat
     3961 ggtcgccatc ttgagttcct cgacctgctg gcaatcacca ttccatcgac gttaatcggt
     4021 atcctggcga tcggtatctt cagctggttc cgcggtaaag atctggataa agacgaagag
     4081 ttccagaaat tcatctccgt accggaaaac cgtgagtatg tttacggtga taccgcgacg
     4141 ctgctggata aaaaactgcc gaaaagcaac tggctggcaa tgtggatctt cctcggggca
     4201 atcgctgtag tcgcccttct tggtgctgat tcggacctgc gtccatcctt cggcggcaaa
     4261 ccgctgtcga tggtactggt tattcagatg tttatgctgc tgaccggggc gctgattatt
     4321 atcctgacca aaaccaatcc cgcgtctatc tcaaaaaacg aagtcttccg ttccggtatg
     4381 atcgccatcg tggcggtgta cggtatcgca tggatggctg aaaccatgtt cggtgcgcat
     4441 atgtctgaaa ttcagggcgt actgggtgaa atggtgaaag agtatccgtg ggcctatgcc
     4501 attgttctgc tgctggtttc caagtttgta aactctcagg ctgcggcgct ggcggcgatt
     4561 gttccggtcg cgctggcgat cggcgttgat ccggcataca tcgtggcttc agcaccggct
     4621 tgctacggtt attacatcct gcggacttat ccgagcgatc tggcagcgat tcagtttgac
     4681 cgttccggca ccacccacat cggtcgcttc gtcatcaacc acagctttat tctgccgggg
     4741 ttgattggtg tgagcgtatc gtgcgtcttc ggctggatct tcgccgcgat gtacgggttc
     4801 ttataaatgc actttgcgtg ccgcccgtaa ctacgcggca cgccattttc gaataacaaa
     4861 tacagagtta caggctggaa gctatgtcaa acaaaccctt tatctaccag gcacctttcc
     4921 cgatggggaa agacaatacc gaatattatc tactcacttc cgattacgtt agcgttgccg
     4981 acttcgacgg cgaaaccatc ctgaaagtgg aaccagaagc cctgaccctg ctggcgcagc
     5041 aagcctttca cgatgcttct ttcatgctcc gcccggcaca ccagaaacag gttgcggcta
     5101 ttcttcacga tccagaagcc agcgaaaacg acaagtacgt ggcgctgcaa ttcttaagaa
     5161 actccgaaat cgccgccaaa ggcgtgctgc cgacctgcca ggataccggc accgcgatca
     5221 tcgtcggtaa aaaaggtcag cgcgtgtgga ccggtggcgg tgatgaagaa gcactgtcga
     5281 aaggcgtcta taacacctat atcgaagata acctgcgcta ttcacagaac gcgccgctgg
     5341 acatgtataa agaggtcaac accggcacga acctgcctgc gcaaatcgac ctgtacgcgg
     5401 tagatggcga tgagtacaaa ttcctctgtg tcgctaaagg cggcggctct gccaacaaaa
     5461 cgtatctcta ccaggaaacc aaagccctgc tgacgcccgg caaactgaaa aacttcctcg
     5521 tcgagaaaat gcgtaccctc ggtactgcag cctgcccgcc gtaccatatc gcgtttgtga
     5581 ttggcggtac gtctgcggaa accaacctga aaaccgtcaa gttagcaagc gctcactatt
     5641 acgatgaact gccgacggaa gggaacgaac atggtcaggc gttccgcgat atccagctgg
     5701 aacaggaact gctggaagag gcacagaaac tcggtcttgg cgcgcagttt ggcggtaaat
     5761 acttcgcgca cgacatccgc gttatccgtc tgccacgtca cggcgcatcc tgcccggtag
     5821 gcatgggagt ctcctgctcc gctgaccgta acattaaagc gaaaatcaac cgcgaaggta
     5881 tctggatcga aaaactggaa cacaacccag gccagtacat tccacaagaa ctgcgtcagg
     5941 caggtgaagg cgaagcagtg aaagtcgacc ttaaccgccc gatgaaagag atccttgccc
     6001 agctttcgca atacccggta tccacccgct tgtcgctcac cggcaccatt atcgtgggtc
     6061 gcgatattgc acacgccaag ctgaaagagc tgattgacgc cggtaaagaa ctgccgcagt
     6121 acatcaaaga tcacccgatc tactacgcgg gtccggcgaa aacgcctgcc ggttatccat
     6181 caggttcact tggcccaacc accgcaggtc gtatggactc ctacgtggat ctgctgcaat
     6241 cccacggcgg cagcatgatc atgctggcga aaggtaaccg cagtcagcag gttaccgacg
     6301 cgtgccataa acacggcggc ttctacctcg gtagtatcgg cggtccggcg gcagtactgg
     6361 cgcagcagag catcaagcat ctggaatgcg tcgcttatcc ggagctgggt atggaagcta
     6421 tctggaaaat cgaagtagaa gatttcccgg cgtttatcct ggtcgatgac aaaggtaacg
     6481 acttcttcca gcagatcgtc aacaaacagt gcgcgaactg cactaagtaa cctcttcggc
     6541 ccagcgcctg gcagcatgct gccaggtgat ccccctgggc cacctctttt gcgattgtaa
     6601 tttcacgctt gctggtgaat agtcagtatt ttccctgact tgcgaactca ccatgacccg
     6661 cacactcaag ccgttaattc ttaacactgg cgcactggcg ctaacgttaa tcctgattta
     6721 taccggcatt tcggcccatg acaaactcac ctggctgatg gaagtgacac cggtgattat
     6781 tgtcgtgccg ctactgcttg ccaccgctaa acgttatccg ttaacgccgc tgctttatac
     6841 gctcattttc tttcacgcca tcatcctgat ggtcggcggg caatacacct acgcgaaagt
     6901 ccccgttggt tttgaggtgc aggaatggct ggggttgagc cgtaatccgt atgacaaact
     6961 gggacatttt ttccaggggc tggtgcctgc actggtggca cgagagatcc ttgtacgcgg
     7021 gatgtacgtt cgcggacgta agatggtggc gtttctggtc tgctgcgtgg cgctggcgat
     7081 aagcgcgatg tatgaattaa tcgagtggtt ggcagcgctg gcaatgggcc agggagctga
     7141 tgattttctc ggcacccagg gcgaccagtg ggacacgcaa tccgatatgt tctgcgcgct
     7201 gcttggcgca ttaacgacgg tgatattcct cgctcgcttt cattgccgcc agctacggcg
     7261 ctttggctta atcaccagag cgccggaagc gattacccct taacggtgca accagcctgg
     7321 cagccagtcg ccgtgggcgg caatcaggtc gtcaacaaga gcatatattt cgtcaatgcc
     7381 cagcacggcg gcagtatgcg ggtccatcat cgcggcgtgg taaacacggt cgcgattttc
     7441 cgtaagaata gcttctgtca gcagcgtctg tacgttgatg ttggtttgca tcagggcggc
     7501 cagatgcgaa ggtagcgtac cggctttggt cggctgaatg ccattagcat caaccagaca
     7561 ggccacttcc acgcaacatc cttgtggcag gttatcaatc aaaccatcgt tacggacatt
     7621 gccataaatc acactcggct cgccagtcca gatagcgttc atgattgtgc tggcatattc
     7681 ccgtgacggt ttaatatcaa tccgggaggc gtttttataa tcctccagct ctttatgcca
     7741 gttcgccagc tgctcgacgc agcgtttcgg gtactcatcc agcggtactt tataacgctc
     7801 aatcaaatcc tcacgacctg gcttaataaa ccacggtgtg tactcagcaa aatgttctga
     7861 cgattctgtg acgaagtagc ccagcttttt gaacatttcg taacgcacaa tattctggca
     7921 gcgagtatta ccatgaatat ttggcttcgg tgcctgccct gcttcataag ccgccagcaa
     7981 ttcaggatag agattcacgt agctaccgtc tgcggtttta cgctccagtt ccaggtaaaa
     8041 cgccatatgg ttgatacctg cgcaacggta acgcagcgta gccggatcga tattgaggtc
     8101 acgcgccagc tcttccgccg ttccctgcac cgaatggcac agccctacct gcttgatatg
     8161 cggatagcgt gcatacatcg cccaggtatt catcgccatt gggttaacgt agttgagcat
     8221 ggtggcatcg gggcagactt ccgtcatgtc ctcgcaaatc tgccacaggt gcggaatggt
     8281 acgtagcgca cgcataatgc cgcccggccc cagcgtatcg gcaatggttt gttccagacc
     8341 atgccgctta cagacctcga aatcagtcac cgtgcaaggt tcataaccgc caatctgaaa
     8401 tgccaccacc acaaaatcag catcctgtaa ggcttctttc tgttgggtgt ggcaggtgat
     8461 tttgccgctg gcccctgctg aatccatcaa cttgcgcacc acaatgtgtg actcttccag
     8521 gcgggtggga tcgatatcca tcagggcaat atgcgccgtt ttcagcgcct cacgatggaa
     8581 cacatcacca agaatatttt taacgaaaat cgtcgaacca gcgccgataa atgtaatttt
     8641 aggtgcagac atcatgcaga tctcctggct tgcttgaatg acttcatcat ggcaggcgaa
     8701 tctgcagaaa acctccggct tccaggttga gcattcccat aaactcatat cctaagtggc
     8761 acatcaatag atctgagttt atgggaataa attacctgaa aagctgaata atcgacccca
     8821 atcttctcat ccgctctcct cgcacctcca gggagaggaa taaaaccgtg cgcctattcg
     8881 cagtcatcct ccctcactcc tgccataatt ctgatattcc aggaaagaga gtcatccatg
     8941 aatacagata cgtttatgtg cagcagcgac gaaaagcaga cccgtagccc actgtcgctg
     9001 tattcagaat accagcggat ggaaattgag tttcgcgcac cgcatatcat gcccaccagc
     9061 cactggcatg gtcaggtcga agtgaatgtg cctttcgatg gcgatgtgga atacctgatc
     9121 aacaatgaaa aagtgaatat caatcagggt catatcacgc tgttctgggc ctgtacaccg
     9181 caccaactaa cagataccgg aacctgtcag agcatggcga ttcttaatct gccgatgcat
     9241 ctgtttctct cctggccgct ggataaagac ctgattaacc acgttactca cggcatggtg
     9301 atcaaatcac tggcgacaca gcaacttagc ccgtttgaag tgcgccgctg gcagcaggaa
     9361 ttaaacagtc cgaacgagca aattcgccag ctcgccattg atgaaattgg cctgatgctc
     9421 aagcgattta gcctctctgg ctgggaaccg attctggtca ataaaacctc gcgcacacac
     9481 aaaaacagtg tctcgcgcca tgcgcaattt tatgtcagcc agatgctggg ctttattgcc
     9541 gaaaactatg atcaggcgct gaccatcaac gatgtggctg agcacgtcaa acttaacgcc
     9601 aactatgcaa tggggatatt ccagcgggtc atgcaattga cgatgaaaca gtacataacc
     9661 gcgatgcgca tcaaccacgt tcgcgcatta ctgagcgata ccgataaaag tattctcgat
     9721 attgccctga cggcaggctt tcgttcgagt agccgttttt acagcacgtt cggcaaatat
     9781 gtcggcatgt cgccgcaaca ataccgcaaa cttagccaac agcgccgcca gacgtttccc
     9841 ggctaaagac gatatcagta tc
//
LOCUS       DAPOXO010000139         9841 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPOXO010000139 DAPOXO010000000
VERSION     DAPOXO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9841
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.139"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..404)
                     /gene="folK"
                     /locus_tag="ROH59_004667"
     CDS             complement(<1..404)
                     /gene="folK"
                     /locus_tag="ROH59_004667"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDX4807059.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESRILAVSSFYRTP
                     PLGPQDQPDYLNAAVALKTTLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAP"
     gene            complement(401..1819)
                     /gene="pcnB"
                     /locus_tag="ROH59_004668"
     CDS             complement(401..1819)
                     /gene="pcnB"
                     /locus_tag="ROH59_004668"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HDX4807060.1"
                     /translation="MTLPRCTIFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQH
                     AISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEY
                     HLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLL
                     ETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDE
                     EPSPRRRTRRPRKRAPRREGTT"
     gene            complement(1858..2784)
                     /gene="gluQRS"
                     /locus_tag="ROH59_004669"
     CDS             complement(1858..2784)
                     /gene="gluQRS"
                     /locus_tag="ROH59_004669"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001432381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HDX4807061.1"
                     /translation="MLPPYFLFKEMTDTHYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWL
                     HEQGLSYYCTCTRARIQNIGGIYDGHCRDLHHGPDNAAVRIRQQHPVTQFTDLLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALHFLGQQVETHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     gene            complement(2821..3276)
                     /gene="dksA"
                     /locus_tag="ROH59_004670"
     CDS             complement(2821..3276)
                     /gene="dksA"
                     /locus_tag="ROH59_004670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HDX4807062.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3454..4158)
                     /gene="sfsA"
                     /locus_tag="ROH59_004671"
     CDS             complement(3454..4158)
                     /gene="sfsA"
                     /locus_tag="ROH59_004671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDX4807063.1"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAIICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     LSAEGMALKKSLPVTL"
     gene            complement(4173..4703)
                     /gene="thpR"
                     /locus_tag="ROH59_004672"
     CDS             complement(4173..4703)
                     /gene="thpR"
                     /locus_tag="ROH59_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HDX4807064.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYTVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            4777..7206
                     /gene="hrpB"
                     /locus_tag="ROH59_004673"
     CDS             4777..7206
                     /gene="hrpB"
                     /locus_tag="ROH59_004673"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HDX4807065.1"
                     /translation="MSSLPVAAVLPELLAALDGASQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDEAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLTSRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLVTQRVSQASMTQRAGRAGRLEPGICLH
                     LIAKEQAERAAAQSEPEILQSDLSCLLMELLQWGCSDPAQMSWLDQPPTVNLLAAKRL
                     LRMLGALDGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFLRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPRLAGAYADRIARRRGQEG
                     RYQLANGMGAMLDADDALSRHEWLIAPLLLQGSSSPDARILLALPVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLATLETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWVMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEASN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            7300..9825
                     /gene="mrcB"
                     /locus_tag="ROH59_004674"
     CDS             7300..9825
                     /gene="mrcB"
                     /locus_tag="ROH59_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HDX4807066.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQQPAQQEQKDSDGVAGWIKEMFGSN"
BASE COUNT         2255 a         2511 c         2814 g         2261 t
ORIGIN      
        1 tccggcgcaa tttcaaacag tggccacagc ataaagccac gatttttcat atcgtagtgc
       61 ggaacggtca gacgttcggt atttattact tcattaccaa acagcatgat gtcgagatcc
      121 agcgtgcgcg gtccccagcg ttcagcttta cggacgcgac cttgctgcaa ttcgatacgc
      181 tgtgtgtgat tgagtagctc ttcaggggca agagtggttt tcagcgcgac ggcggcattt
      241 aagtaatcgg gttgatcttg cggccccaga ggtggggtgc ggtaaaacga agaaacggca
      301 agaatgcggc tttctggaat atcgcctaat gctttcaggg cagcattgac ctgctccagc
      361 ggagaggcca gattgctgcc tatggcaata tacgccactg tcatgtagta ccctcacgac
      421 gcggtgcgcg tttgcgtgga cgacgagtac gacgacgcgg tgacggttct tcatccagtt
      481 cgttaagcat ccctttttgg tctggcggcg cggaaacctg gaactcaccc caccatttca
      541 ccagacgttg cagttcagcg ttacgctcaa cttcggctcg taaggccaac aggtcgtatg
      601 ccgcacggaa cttaggatgc tccagcagtt tccatgcgcg tttaccctga cgacgggaca
      661 tacgcaactg caactgccag atatcgcgag ttagcgtagt cagacgtttc gggatcgcca
      721 gtgaacggca ggcttcgtcc agcacgtcgt tcatcgccag tgcgaaagcg tcgtgatagg
      781 tcaggccgct ctcctgagca attttctgtg ccgtctccag caatgggtac cagaacatgg
      841 cggcaaacag gaacgccggg ttcacgcgca tatcgttatg gatacgcgta tcggtattct
      901 tcagtacctg ctcaataatg cgttccatcg ggctgtcgcc attttccgtg aagtagcggg
      961 taatggtcgg gaacagcggc tggaacagat gatattcaca cagcagctta taggtttcgt
     1021 aaccgtagcc cgcttgcaac agtttcagcg attcttcaaa cagacgtgcc ggtgggatat
     1081 cgttcagtaa ggttgccagg cgtgggatcg gctcggcggt ttccgggctg atgcgcatgc
     1141 ccaatttggc ggcaaaacga accgcgcgga gcatacgtac cggatcttca cggtagcgcg
     1201 tttccgggtt accaatcaga cggataacgc cgtctttcag atccttcatg ccgccaacgt
     1261 aatcacggac ggtaaaatct gccacgctgt aatacaggct gttgatagtg aaatcgcggc
     1321 gctgggcgtc ttcttcgatg gagccgaaaa tgttgtcgcg cagcaacata ccgttttgcc
     1381 cgcgttggga ggtcgtgcgg tcgctgacgt taccttcgtg atgtccacgg aaggtcgcaa
     1441 cttcgataat ctccgggcca aacatcacat gagccagacg gaaacggcga cccaccagac
     1501 ggcagttacg gaacagttta cgtacctgtt caggcgtggc gttagtggtt acgtcaaaat
     1561 ctttcggctt tttgccaagt aacaggtcgc gcacgccgcc gccaaccagc caggcttcgt
     1621 atcccgcttt attgagcctg tacattacct tcagggcatt ttcactgata tctttgcggg
     1681 aaatagcatg ctgctcacgc gggatcaccg tcacctgtgg acgggcgact gcctgttcag
     1741 cctcgctttc ctcgcggctt agcaccttgc ggcaaaaatt agcgactcgg gtaaaaatag
     1801 tacacctcgg tagtgtcaaa catcattcag gacaaaaaaa tagcggctaa tcatagctca
     1861 gcatgacgca tttgagaatg ttgaatttac aattgccgac tcaggcactg cggtgagccg
     1921 ccagtttttg acggctgact gaaggatttg ctcgacgctg aaatcctgcc agtgtgtttc
     1981 tacctgctga cccagaaaat gaagtgccgc gattaacacc gggcgcggat cgcctttcgg
     2041 caacgcaggc gcatgattct gcttggaaag tttagcgcct tgtggattaa gcgccagcgg
     2101 taaatggatg taatctggca ctttccagcc aaaaagctgg tacagcgaga tttgccgcac
     2161 agtcggttcg atcaaatctg ccccgcggac aatttcgctc acgccctgga agtgatcatc
     2221 caccaccacc gccaggttat aggcaaacaa accatcacgg cgatgaataa taaaatcttc
     2281 ccgtgccagt ttttcgtcgg cgtgaataat gcctcgcagc aggtcagtaa actgggtgac
     2341 tggatgctgc tggcggatac gtactgcggc gttgtctggt ccatgatgca aatcccggca
     2401 atgaccgtcg taaataccgc caatgttttg aatacgcgca cgcgtgcagg tgcagtaata
     2461 acttagtcct tgctcatgta accaggcgag tgcttcgcga taggcgtggt gacgttgcga
     2521 ttgccagaga acgtcgccgt cccagtgtag gccgtaatgt tccagctggc gcaggatagt
     2581 ctctgcggca ccgggaactt cacgaggcgg gtcgatatct tcaatgcgta ccagccagcg
     2641 accttgccgg gcgcgagcct gcaaatagct gccaagcgca gcaatcagag aaccaaaatg
     2701 aagctcgccg gaaggagagg gggcgaagcg accaatatag tgtgtgtctg tcatctcttt
     2761 gaacaaaaaa taaggcggga gcatttcccg cctgtggtaa acatgatgga acggctgtaa
     2821 ttagccagcc atctgttttt cgcgaatttc agccagcgtc ttgcagtcga tgcatagatc
     2881 ggctgtcggg cgcgcttcca gacggcgaat accaatttca acaccgcagg attcgcagta
     2941 gccgaaatct tcgtcttcca cttttttcag cgtcttctcg atctttttga tcagcttacg
     3001 ctcgcgatcg cggttacgca gttcgaggct gaactcttct tcctgggctg cacggtctac
     3061 cgggtccggg aagttggctg cttcatcctg catatgtgta acggtgcgat cgacttcatc
     3121 cctgagttga ttacgccatg cttccagaat acgacggaag tgcgccagct gggcttcatt
     3181 catatactct tcgcccggct tctcctgata tggttccacc ccagcgatgg cgagaatact
     3241 cagggacgat gttttacggt tttgcccttc ttgcatgttg cttctcctta acacgcacta
     3301 tcgatcccca tgttcggggg aaaaatgagg ccgctataaa tagcagatgc ttttccggat
     3361 agcaattatc taaacgtaac acttgacaac tgtgtgagga aaagcgtatt tgcgcacgcg
     3421 accagaatgt aaattaacca gttacttact ctactacaat gtaaccggta gtgatttttt
     3481 aagagccatg ccttcggcag aaagttccgc tttgtaagcc agaatttcta cccccctctg
     3541 ttgagcttct gacaatagtt gtgcgtattt ctcatcgatg tggcgcgcgg gtgaaaaccg
     3601 tgtaatggct gaatgcagca cggcgaaaaa gataaccgca cgctggcctt cagccgctac
     3661 gctcatcaac tcccgaaggt gtttctgacc tcgttcagtg accgcatcgg gaaaatatcc
     3721 ctgttcgttc tccgctaacg taaccgattt cacttcaata tagcagtctg gacgcgaatc
     3781 cgcctgcaac ataaagtcaa tacggctgcg ttcggcgccg tattttactt cgcttttcag
     3841 cgagctatag cctgacagct ctgaaattga ttcattaagg atagcctctt tcgtcaacct
     3901 gttagcccaa agcgtattga cgcaaataat tgcgccgctt tggctttgag ttaattccca
     3961 ggtgtgtggg tatttccgtt tggtgttgtc tgaagtcgaa taccagacgg tatcgccagg
     4021 cgttgcacaa ccggtcatcg cacccgtatt cgggcagtgt agcgttaatt cgcgaccatc
     4081 gggtgtgatc acatcggcta aaaaacgttt gtaacgctga attagcgtcg cgcgctgtag
     4141 agggggagaa aattccattg cgacaatcct tgttattgcg ttagcgccca gcgttttagc
     4201 ggcgtgtagc gtgtgcgtcc acgggcaaac gaggaggcgt aaagggtgaa ctccgtcacc
     4261 gtatacgacc agttaaaacc tggcggcggg attgtcaccg cctcgctggc gtcgcgcaat
     4321 aaggtaatat gtggatgaaa cggacgattg ctttgaaaac aaccgctgcg ggcagcctgt
     4381 gaacggagca tattcgccag ctggattaag ccgcgtggcg gctgtcgcat ccctaaccac
     4441 accacacgcg aacgcagcca ttgaccggcg tcatcaagcg tgagtgtgaa accaggttga
     4501 cgaatccgtc cggctaaaag agaaagcgcc ttctctttct ctgcgctcac ttcgcctaaa
     4561 aatgccagag tcagatgcaa attatcggcg gcgaccggac gtcccgcctc aggtgggaag
     4621 tgtgtggcgc gccagtggat aatctgttcg cggatttctg caggtaagtc gatagcaaag
     4681 aacagccgtt gcggttcaga catgtgaggc actcggttat gaattaccgc gatgctacaa
     4741 tgtggcgcga agaatgttaa ccctctggag cgttttgtgt cgtcgttgcc cgttgctgcc
     4801 gtcttacctg agttacttgc tgccctcgat ggtgcatcgc aggtgttatt aagtgcgccg
     4861 accggggccg ggaaatcaac ctggctgccg ctgcaactgc tggcgcatcc cggcattaac
     4921 gggaaaatta tcctgctgga gccgcgtcgt ctggcggcgc gtaacgttgc gcaacgactg
     4981 gcggagctgc ttaacgaaaa gccaggcgat accgttggct accggatgcg tgcgcaaaac
     5041 tgcgtcgggc cgaatacccg cctggaagtg gttaccgaag gcgtgctgac gcggatgatc
     5101 cagcgtgacc cggaactgag cggtgttgga ttggtgatcc ttgatgaatt tcatgagcgc
     5161 agcttgcagg cggatttggc gttggcgctg ttactcgatg tgcaacaagg tctgcgtgat
     5221 gaccttaaac tgctgattat gtcggctacg ctggacaacg accgcttgca gcaaatgctg
     5281 ccagaagcgc ccgtcgtcat ctcagaaggg cgctcgtttc cagttgaacg ccgttatttg
     5341 ccgctgcccg ctcatcagcg ttttgacgaa gccgtcgcgg ttgccaccgc cgaaatgctg
     5401 cgtcaggaaa gtggatcatt actgttattt ttacctggcg tcggagaaat tcagcgtgtg
     5461 caggaacaac tgacttcacg catcggcagt gatgtgttgc tctgcccgct gtatggcgcg
     5521 ttgtcgctga acgatcagcg aaaagcgatc ctcccggcac cgcaagggat gcgtaaagtg
     5581 gtgctggcga ccaatattgc tgaaaccagt ttaaccatcg aaggtattcg tctggtggtg
     5641 gattgtgccc aggagcgtgt ggcgcgtttt gatccgcgta cagggcttac gcggctggtt
     5701 actcaacgtg ttagtcaggc gtcgatgacg caacgtgccg ggcgtgccgg gcgtctggag
     5761 ccgggtatct gcctgcattt aatcgccaaa gaacaagcag aacgcgctgc cgcgcaaagt
     5821 gaaccggaaa tattacaaag cgatctttcc tgtttgctga tggaattact gcaatgggga
     5881 tgcagcgatc cggcgcagat gagctggctg gatcaaccgc caacggtgaa tctactggcc
     5941 gcgaaacgcc tgttacggat gctgggggcg ctggacggtg aacggcttag tgcgcaaggg
     6001 caaaaaatgg cagcgctggg taacgatccg cgtttagcgg caatgctggt tagcgcgaag
     6061 aacgacgacg aagctgctac cgcggcaaaa attgccgcca ttctcgaaga gccgccacgg
     6121 atgggcaata gtgacctggg cgtggcgttt ttgcgcaatc aacccgcctg gcagcaacgt
     6181 agtcagcaac tgttaaaacg tttaaacgta cgcggcggtg aggcagacag ttcgcttatc
     6241 gcgccgcgac ttgccggagc gtatgccgat cgtattgctc gccgccgtgg gcaagaggga
     6301 cgctatcaac tggcgaacgg catgggggcg atgctcgatg ccgacgatgc gcttagccgc
     6361 cacgaatggt tgatcgcgcc gttattattg cagggcagtt cttcgccgga tgcgcggatt
     6421 ttactggcgc tgccggtcga tattgatgag ttagtacaac gctgcccgca gctggtacag
     6481 cagtctgaca ccgtggagtg ggatgacgcg caaggtacgc tgaaagcctg gcgtcggctg
     6541 caaatcggtc agttgacggt aaaagtgcaa ccgctggcga aaccctcgga agacgagttg
     6601 catcaggcga tgcttaacgg cattcgtgat aaaggtttaa gcgtgctcaa ctggacggcg
     6661 gaagcggaac agctacgctt gcgtttgtta tgtgccgcaa agtggttgcc ggaatatgac
     6721 tggccagcgg ttgatgatga aagtttgttg gcgacgctgg aaacgtggct actgccgcat
     6781 atgacaggcg tacattcgct acgcggcctg aaatcactcg atatttatca ggcactgcgt
     6841 ggattacttg attgggtaat gcagcaacgt ctggatagtg aattgcctgc gcattacact
     6901 gtgccgacgg gaagccggat cgccattcgt taccatgaag ataacccgcc cgcgctggcg
     6961 gtgagaatgc aggagatgtt tggtgaggcc tctaatccga ctatcgccca ggggcgcgta
     7021 ccgttggtgc tggagttgct ttcccctgcc caaaggccgc tgcaaatcac gcgtgatttg
     7081 agcgccttct ggaaaggagc gtaccgtgag gtgcaaaaag agatgaaagg gcgttatccc
     7141 aaacatgtct ggccggacga cccggcaaac accgcaccga cgcgacgaac gaaaaagtat
     7201 tcgtgaagac caaagcaaat ttgagagata tcttcttctg tcttgcaaca gaagaacaga
     7261 aaatcgggct tttgcgcctg aatattgcgg agaaaaagca tggccgggaa tgaccgcgag
     7321 ccaattggac gcaaagggaa accgacgcgt ccggtcaaac aaaaggtaag ccgtcgtcgt
     7381 tacgaagatg acgatgatta cgacgattat gatgactatg aggatgaaga accgatgccg
     7441 cgcaaaggta agggcaaagg caaagggcgt aagcctcgtg gcaaacgcgg ctggctatgg
     7501 ctgctgctaa aactggctat cgtttttgcc gtgctgatcg ccatttacgg cgtttatctc
     7561 gatcaaaaaa ttcgcagccg tattgatggc aaggtctggc aattgcccgc ggcagtttat
     7621 ggtcgaatgg tcaaccttga gccagacatg accatcagca agaacgagat ggtgaagctg
     7681 ctggaggcga cccagtatcg ccaggtgtcg aaaatgaccc gtcctggtga gtttaccgta
     7741 caggccaaca gcattgagat gatccgccgt ccgtttgatt tcccggacag caaagaaggg
     7801 caggtgcgcg cgcgtctgac ctttgatggc gatcatctgg cgacgatagt caatatggag
     7861 aacaaccgtc agttcggttt cttccgtctt gatccgcgcc tgatcaccat gatctcttcg
     7921 ccaaacggtg agcagcgtct gtttgtgccg cgcagtggtt tcccggattt gctggtggat
     7981 actttgctgg cgacagaaga ccgtcatttc tacgagcatg atgggatcag tctctactca
     8041 atcggacgtg cggtgctggc aaacctgact gccggacgca cggtgcaggg ggcgagtacg
     8101 ctgacgcaac agttggttaa aaacctgttt ctctccagcg agcgttctta ctggcgtaaa
     8161 gcgaacgaag cctacatggc gctgatcatg gacgcgcgtt acagcaaaga ccgtattctt
     8221 gagctgtata tgaacgaggt gtatctcggt cagagcggcg acaacgaaat ccgcggcttc
     8281 ccgctggcga gcttgtatta ctttggtcgc ccggtagaag aattgagcct cgatcagcag
     8341 gcgctgttgg tgggtatggt gaaaggggcg tccatctaca acccgtggcg taacccgaaa
     8401 ctggcgctgg agcgacgtaa cctggtacta cgtttgctgc aacagcaaca aattattgat
     8461 caagaactct atgacatgtt gagtgcacgt ccgctgggtg ttcagccgcg cggtggggtg
     8521 atctctcctc agccagcctt tatgcagctg gtgcgtcagg agctgcaggc gaaattaggc
     8581 gataaggtaa aagatctctc cggcgtgaag atcttcacta cctttgactc ggtggcccag
     8641 gacgcggcag aaaaagccgc cgtggaaggc attccggcac tgaagaaaca gcgtaagttg
     8701 agcgatcttg aaaccgcgat tgtggttgtt gaccgcttta gcggtgaagt tcgtgcgatg
     8761 gtcggtggct ctgagccgca gtttgcgggc tacaaccgtg cgatgcaggc gcgtcgttcg
     8821 attggttccc ttgcaaaacc agcgacttat ctaacggcct taagccagcc gaaaatctat
     8881 cgtttgaata cgtggattgc cgatgcgcca atcgcgctgc gtcagccgaa tggccaggtc
     8941 tggtcaccgc agaacgatga tcgtcgttat agcgaaagtg gcagggtgat gctggtagat
     9001 gcgttgaccc gttcgatgaa cgtgccaacg gtgaatctgg gcatggcgtt ggggctgcct
     9061 gcggttacgg atacctggat caaactgggt gtgccgaaag atcaactgaa tccagttcca
     9121 gcaatgttgt tgggggcgtt gaacttaacg ccaatcgaag tggcgcaggc cttccagact
     9181 atcgccagcg gtggtaatcg tgctccgctt tccgcgctac gttcagtcat cgcagaagac
     9241 ggcaaggtgt tgtatcagag cttcccgcag gcagaacgcg ctgttccggc gcaggcggcg
     9301 tatctgacac tatggaccat gcagcaggtt gtacaacgcg gtacgggacg tcagcttggg
     9361 gcaaaatacc cgaacctgca tctggcaggg aaaacaggga ctaccaacaa taacgtagat
     9421 acctggtttg cgggcattga tgggagcacg gtgaccatca cctgggtcgg ccgtgataac
     9481 aaccagccga ccaaactgta tggtgccagc ggggcaatgt cgatttatca gcgttatctg
     9541 gctaaccaga cgccaacacc gctgaatctt gttccgccgg aagatattgc agatatgggc
     9601 gtggactacg acggcaactt tgtttgcagc ggtggtatgc gtgtcttgcc agtctggacc
     9661 agcgatccgc aatcgctgtg ccagcagagt gagatgcagc agcaaccgtc aggcaatccg
     9721 tttgatcagt cttctcagcc gcagcaacag caacctgctc aacaggagca aaaagacagc
     9781 gacggcgtgg ctggctggat caaggagatg tttggtagta attaatatcg taatcgctct
     9841 c
//
LOCUS       DAPOXO010000140         9775 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.140, whole genome shotgun sequence.
ACCESSION   DAPOXO010000140 DAPOXO010000000
VERSION     DAPOXO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9775
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.140"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(61..996)
                     /gene="dsdC"
                     /locus_tag="ROH59_004675"
     CDS             complement(61..996)
                     /gene="dsdC"
                     /locus_tag="ROH59_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DsdC"
                     /protein_id="HDX4807067.1"
                     /translation="MEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPS
                     AVSHRINQLEEELGIQLFVRSHRKVELTHEGKRVYWALKSSLDTLNQEILDIKNQELS
                     GTLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDDAP
                     SAQLTHNFLMDEEILPVCSPEYAHRHDLTNTVINLRHCTLLHDRQAWSNDSGTDEWHS
                     WAQHYAVNLPTSSGIGFDRSDLAVIAAMNHVGVAMGRKRLVQKRLASGELVAPFGDMT
                     VKCHQHYYITTLPGRQWPKIEAFITWLREQVKTTS"
     gene            1214..2551
                     /gene="dsdX"
                     /locus_tag="ROH59_004676"
     CDS             1214..2551
                     /gene="dsdX"
                     /locus_tag="ROH59_004676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
                     /protein_id="HDX4807068.1"
                     /translation="MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMM
                     GMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSAD
                     VIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
                     HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLK
                     VRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAV
                     FVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVI
                     LSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGS
                     GAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTFLLSFII"
     gene            2569..3897
                     /gene="dsdA"
                     /locus_tag="ROH59_004677"
     CDS             2569..3897
                     /gene="dsdA"
                     /locus_tag="ROH59_004677"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HDX4807069.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKASQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR"
     gene            complement(4005..5543)
                     /gene="emrY"
                     /locus_tag="ROH59_004678"
     CDS             complement(4005..5543)
                     /gene="emrY"
                     /locus_tag="ROH59_004678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HDX4807070.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDLDWFNSSTIILLTVVSVISLISLVIWESTSENPILDLSLFKSRNFTI
                     GIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNK
                     IDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFS
                     GLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSS
                     SQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTA
                     KGVG"
     gene            complement(5543..6706)
                     /gene="emrK"
                     /locus_tag="ROH59_004679"
     CDS             complement(5543..6706)
                     /gene="emrK"
                     /locus_tag="ROH59_004679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HDX4807071.1"
                     /translation="MEQINSNKKHSDRRKYFALLAVVLFIALSGAYAYWSMELKDMIS
                     TDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKAKNNLA
                     NIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKEALEHTKDTL
                     ISSKAALNAAIQAYKANKALVMNTPLNRQPQVIEAADATKEAWLALKRTDIKSPVTGY
                     IAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGENV
                     VFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEHPLRIGLSM
                     TATIDTKNEDIAEMPDLASTVTSMPAYTSKALVIDTSPIEKEISNIISHNGQL"
     gene            7122..7736
                     /gene="evgA"
                     /locus_tag="ROH59_004680"
     CDS             7122..7736
                     /gene="evgA"
                     /locus_tag="ROH59_004680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HDX4807072.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            7741..>9775
                     /gene="evgS"
                     /locus_tag="ROH59_004681"
     CDS             7741..>9775
                     /gene="evgS"
                     /locus_tag="ROH59_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HDX4807073.1"
                     /translation="MKFLPYIFLLCCGLWSTISFADGDYIEYRGISSNNRVTLDPLRL
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRIRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALEDGEVDIVLSHLVASPPLNDDIAATNPLIITFPALVTTLHDSMRPLT
                     SSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFLLTRKDSIVLNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDETGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLNPGGWDILPAAIYSEDRENNVSFAEVFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIKVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVQNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     ESPFKDVFSNTHEVTAETKENRKIYTQVFEIDNGIEKRCINHWHTLCNLPASEH"
BASE COUNT         2746 a         2152 c         2109 g         2768 t
ORIGIN      
        1 ttattaaatt cgcactagca gtgccgaata aggcacacca ggaactcgtg gtcttattca
       61 ttatgaagtg gtttttacct gttctcttaa ccaagtaata aatgcctcaa tttttggcca
      121 ctgcctgccc ggtaatgtgg tgatgtaata atgctgatgg catttcaccg tcatatcgcc
      181 aaacggcgcg acgagctcac cactggcaag ccttttttgt accaggcgtt tccttcccat
      241 cgccacccca acatgattca tcgcggcgat aacggctaaa tcagaacgat caaagccaat
      301 tccagaagat gtcggcaaat taaccgcata atgttgcgcc caactatgcc attcatccgt
      361 accggagtcg ttgctccatg cctgtctgtc atggagcaac gtacagtgac gcaggttaat
      421 taccgtgttg gttaaatcat gtctatgagc gtactccggg ctacaaactg gcaagatttc
      481 ttcatccatc agaaagttat gggtcagttg cgctgacggc gcatcatcaa agtagatcgc
      541 caaatcgatt ccggcacgtt gcaaattgac attgtcatta ccagtgagca cggtgagcga
      601 aatagacgga tatcggcgtg taaagtcacc taatgcgggc accaaccagc attgggcgat
      661 agagggccgg gaatacagag ttaacgttcc cgataactcc tgatttttga tatccagaat
      721 ttcctgattc agggtatcca gcgacgattt tagcgcccaa taaacgcgtt tcccctcgtg
      781 cgttaattcc actttgcgat gggaacgaac aaacaactga atacctaatt cttcttccag
      841 ctgattgata cggtgactta ccgcactggg gctcagcgac aattcctctg ccgccagggc
      901 gaaagactga tgcctggcag ccacttcaaa agtatgcagt tttgatagtt gccagccgtt
      961 aagcagtcga tttcttattt cacgaagggg ttccataatc acctcatttt tctattaagt
     1021 gtaaaaaaat agcggcaaaa tttcagctgt aaggtgagct aaagtgaacc atatctcaat
     1081 tcaccttcat ttttagatgt aaatcactcc cttgatgcaa tttagctcat gtgaaaggca
     1141 aattttatcg tttgtcagcc tgcgttgttt ttttgtccaa tatcatcagg ttaatcacag
     1201 gggaaggtga gatatgcact ctcaaatctg ggttgtgagc acgctgctta tcagcatcgt
     1261 gttaattgta ctgaccatcg tgaagttcaa attccacccg tttctggcgc tgttgctggc
     1321 cagcttcttc gtgggaacga tgatgggtat ggggccactg gatatggtaa atgctattga
     1381 aagtggaatt ggcggaacgc tggggttcct cgctgcggtt atcggccttg gcacgatact
     1441 gggaaaaatg atggaagtat ccggggccgc agaaagaatt ggtctgacac ttcaacgctg
     1501 ccggtggctt tcggctgatg tcattatggt gctggttggc ctgatttgcg gcatcacgct
     1561 gtttgttgaa gtgggcgtcg tgctattgat tcctctggct ttttcaattg ccaaaaaaac
     1621 caatacctca ttgttaaagc tggccattcc gctgtgtacc gcattgatgg ctgtgcactg
     1681 cgtggttccc ccacatccgg ctgctttata tgttgccaat aagctgggcg cagatatcgg
     1741 ttcggtgatc gtctacggtt tgctggttgg gctgatggca tcactgatcg gtggcccact
     1801 tttccttaaa tttctggggc aacgactgcc ctttaaacct gtacccacag agtttgccga
     1861 tctcaaagtt cgcgatgaaa aaacactacc ttcattaggc gcaacgttat tcaccatact
     1921 gctacccatt gcgctgatgt tggttaaaac gattgccgaa ttgaatatgg cgcgtgagag
     1981 tggtttgtat accttgcttg agtttattgg caaccctatc actgccatgt ttatcgccgt
     2041 gtttgtcgcc tattatgtgt tgggtatacg tcagcatatg agcatgggga cgatgctcac
     2101 acatacggaa aatggtttcg gttctattgc taatattttg ctgattatcg gggccggagg
     2161 cgcattcaac gccattttaa aaagcagcag tctcgctgat acgctggcag ttattctctc
     2221 caatatgcat atgcacccga ttcttctggc ctggttggtg gcacttattc tgcatgctgc
     2281 agtgggctcc gctacggtgg caatgatggg ggcaacggca attgttgccc ccatgctgcc
     2341 gctgtatccc gacatcagcc cggaaattat tgcgattgct atcggttccg gtgcgattgg
     2401 ctgcacgatc gttacggact cgcttttctg gctggtgaag caatattgcg gcgctacgct
     2461 caatgaaaca tttaaatact atacgacagc gacatttatc gcttcggtca tcgctctggc
     2521 gggcacattc ctgctgtcat ttatcatcta agcgcaaaga gacgtactat ggaaaacgct
     2581 aaaatgaatt cgctcatcgc ccagtatccg ttggtaaagg atctggttgc tcttaaagaa
     2641 accacttggt tcaatcctgg cacgacctca ttggctgaag gtttacctta tgttggcctg
     2701 accgaacagg atgttcagga cgcccatgcg cgcttatctc gttttgcccc ctatctggca
     2761 aaagcatttc ctgaaactgc tgccactggg gggattattg aatcagaact ggttgccatt
     2821 ccggctatgc aaaaacggct ggaaaaggaa tatcagcaac cgatcagcgg gcaactgtta
     2881 ctgaaaaaag atagccattt gcctatttcc ggctccataa aagcacgcgg cgggatttat
     2941 gaagtcctgg cacatgcaga aaaactggct ctggaagcag ggttgctgac gcttgaagat
     3001 gactacagca aactgctttc tccggagttt aaacagttct ttagccaata cagcattgct
     3061 gtgggctcaa ccggaaatct ggggttatca atcggtatta tgagcgcccg cattggcttt
     3121 aaggtgacag tgcatatgtc tgctgatgcc cgggcatgga aaaaagcgaa actgcgcagc
     3181 catggcgtta cggtcgtgga atatgagcaa gattatggtg ttgctgtcga ggaaggacgt
     3241 aaagcatcgc agtctgaccc gaactgtttc tttattgatg acgagaattc ccgcacgttg
     3301 ttccttgggt attccgtcgc tggccagcgt cttaaagcgc aatttgccca gcaaggccgt
     3361 atcgtcgatg ctgataaccc tctatttgtc tatctgccgt gtggtgttgg cggtggtcct
     3421 ggtggcgtcg cattcggact taaactggcg tttggcgatc atgttcactg cttttttgcc
     3481 gaaccaacac actccccgtg tatgttatta ggcgtccata ccggattaca cgatcagatt
     3541 tctgttcagg atattggcat cgacaacctt accgctgccg atggccttgc ggttggtcgc
     3601 gcatcgggct ttgtcgggcg ggcgatggag cgtctgctgg atggcttcta tacccttagc
     3661 gatcaaacca tgtatgacat gcttggctgg ctggcgcagg aagaaggtat tcgtcttgaa
     3721 ccttcggcac tggcgggtat ggccggacct cagcgcgtgt gcgcatcagt aagttaccaa
     3781 cagatgcacg gtttcagcgc agaacaactg cgtaatgcca ctcatctggt gtgggcgacg
     3841 ggaggtggaa tggtgccgga agaagagatg aatcaatatc tggcaaaagg ccgttaataa
     3901 cgtttcaacg cagcatcacc atcctttccc tgggtgagcg atgctgccga tgacgcagac
     3961 ttaagattct gccgttttac ctgctatagc ctcctctttt tccatcaccc aacgcctttc
     4021 gctgtaaacg gcggtttcgc aaaccaaacc aaaaccgtaa gtaagataaa agcaatagcc
     4081 gccatacgga aaatctcatt tgcagaaata gaaagtgact gctgagttat ttcattatta
     4141 atttcattaa gaactcctga aagcgaacca tagtatttat ccataatttg tgacgatgaa
     4201 ttaaacacgg ggttaaattg atcgatggtt gctgtcaact gactatggtg taacgattcg
     4261 cggcgtcccc acagtgtcat tgtcaacgac gtaccaactg atcctgacaa ggtgcgaaaa
     4321 aaattactca tactcgaggc attggcaaat ttattatctg gcaagcctga aaacgaaatc
     4381 gttgttaagg gtaaaaagaa acaggcaacg gcgaatccct gaaaaaactg tggcaaaatg
     4441 atgcctgtaa aatcaatcgt tggcataaat gtcacagaac gccagtaata gcaaaccgca
     4501 tacatcaaaa aactaaatgt caccaacaac cgcatatcaa ttttgttgcc ataacgtcct
     4561 atcaaaggtg atattaatag cggcatgata ccgatgggcg cataggcaag tccggcccat
     4621 atcgcattat accccatcgt ttcctggagt aactgcggca taagaactat cgctccagag
     4681 taaaataaat acgcgcatgt gatactcaca ataccaatgg tgaaattacg ggacttaaac
     4741 aaactgaggt caagaatcgg attctctgag gtcgactccc aaatgactaa agagatcaga
     4801 gaaataactg atactactgt tagtagtatt attgtactcg agttgaacca atccagatcg
     4861 cgccctttat caagcataat ttgcaagcca ccaacaccga gcactaacag ggtcagtcct
     4921 ggtagattca ttttgaccgg tgaagtctca gtttctcgtc ctttaagtaa ggttaagcat
     4981 aatgtcagga cgataatccc catagggaca ttgattaaaa atatccaacc ccagctaaag
     5041 ttatcgcaaa tatagccgcc caatatcggc ccacatatcg gagcgataat cacggtcatt
     5101 gaccataatg ccagagcaaa tgttcttttt tctggtggat aattccttaa taataaactc
     5161 tgtgacagtg gaattaacgg ccccgccatt aacccctgaa cgactctaaa aaatatcagc
     5221 acatcaagat tggtcgataa actacacatt aatgaagaca gcgaaaaaaa ggttactgaa
     5281 agtaaaaata accttaattc gcctattctt tgtgccagcc tgccggtaac agggatcgca
     5341 atggcatttg ctacgccaaa cgaggtgata acccaggtac cttcgtctgt tgatgctccc
     5401 agaaagccag atattgtcgg tattgcgacg ttagaaatag tggaatccaa catttgcata
     5461 aacgtcgcta atgacaatgc aatagtgacg caccataacg tcccaccggt taatggtgca
     5521 ggagttgatt tagtgattgc cattaaagtt gtccattatg cgaaataatg ttgctaattt
     5581 ctttttctat cggactggta tcgataacta aagccttact ggtataagca ggcatggacg
     5641 tcacggttga agccagatcg ggcatctcgg caatgtcttc attcttcgta tcaatagttg
     5701 cagtcatcga taaaccaatg cgcaaagggt gttccatgag ttcttttgga tccagagaaa
     5761 cttcaaccgg tacacgctga acgattttga tccagttccc tgtcgcattt tgtgcaggta
     5821 ataaggagaa cgcattgccg gttcccatat tgatccctgt cacccgacca tgaaacacaa
     5881 cattttcacc ataaagatcg ctgataatat tgaccgattg accaatccgt acatccgtga
     5941 gttgtgtttc tttaaagttg gcattaaccc acatttgacg cgccggtacg acagccatta
     6001 acgattgtcc gggactcact gtttcgccga cctgaacact tctctgggca atataaccgg
     6061 taaccggact cttaatatcc gtacgtttaa gcgccaacca ggcttctttg gttgcatctg
     6121 cagcttcaat gacttgtggc tgacggttta atggtgtgtt cattactaaa gctttattcg
     6181 ctttataagc ctggatagca gcattcaatg ccgctttgct acttattaac gtatctttgg
     6241 tatgctccag cgcttctttt gaaataaccc cttgcttcgc taaaggcaca cgacggttat
     6301 aatcttctaa agattgttga tactgaatac gtgctgaagc gacttcggca ctgtattgtt
     6361 tatcctgtaa gtatagttta ttcgtttgcc gaacaatatt tgccagatta tttttagctt
     6421 tattgagtgc gatagtggca tcagttttat ccagtgaaac taaaatgtca ccttgtcgaa
     6481 cgtagttcgt atctttatga ttaacgacag tgacactgcc tgagacttgt gcagaaattg
     6541 gatctgcatt tcccgtgaca taggcgtcat ctgtactaat catgtctttt aattccattg
     6601 accaataggc ataggcacct gaaagcgcaa taaataaaac taccgctaac aaagcaaaat
     6661 attttcttct gtcagaatgt tttttatttg aattaatctg ttccactatt atctctcatt
     6721 tcgcatagat gaaatttatg aattgaatga aaagagtatt cattcctcat atcaaacaca
     6781 gtgcatgttt tgcacattat cccaggaacg ttggagggct aatttaaatg aggtgcaaaa
     6841 aaaacaacag aggactaaac cgcggctttt gcaatacaat tcttacgcct gtaggattag
     6901 tgagaaaact tatagtgctc atttgaaact ataaatcatc ggtatcatcc ctgattttat
     6961 tgttgacatt ttatttatgc cgactattta tatggtatac ttgtcgaatt atcttaaagg
     7021 aagctcaaat tttcttattt ttattgagaa aatgagatga taccttatgt ctgtattact
     7081 acagggagaa gggaaatgct tcattgcaaa gggaataatc tatgaacgca ataattattg
     7141 atgaccatcc tcttgctatc gcagcaattc gtaatttatt gatcaaaaac gatattgaaa
     7201 tcttagcaga gttgactgaa ggcggaagcg ccgttcagcg ggtggaaaca cttaagcctg
     7261 atatcgtcat cattgatgtc gatatccccg gagttaacgg tatccaggtg ttagaaacgc
     7321 tgagaaagcg ccaatatagc ggaattatta ttattgtctc cgctaaaaat gaccattttt
     7381 acgggaaaca ttgtgctgat gctggcgcta atggtttcgt gagtaaaaaa gaaggcatga
     7441 acaatatcat tgcagctatt gaagctgcaa aaaatggcta ctgctatttc cccttctctc
     7501 tcaaccggtt tgttggaagt ttaacgtccg accagcaaaa actcgactcc ttatcgaaac
     7561 aagaaattag tgtcatgcgg tatattcttg atggcaagga taataatgac attgctgaaa
     7621 aaatgttcat cagcaacaaa actgtcagca cttataaaag tcgcttgatg gaaaaattag
     7681 aatgcaaatc actgatggat ctttacacat tcgcacaacg taacaaaatc ggctaaccac
     7741 atgaagtttt taccctatat ttttcttctc tgttgtggtc tttggtcgac cataagtttc
     7801 gcagacggag attacatcga atatcgtggc atcagtagta acaaccgtgt cacacttgat
     7861 ccactacgtc tgagcaacaa ggaattacgt tggctagcga gcaaaaaaaa tcttgtgatt
     7921 gcagtacaca agtcccaaac agctacgttg ttgcataccg attcgcagca acggattcgt
     7981 ggtattaatg ctgattattt aaatctttta aaaagagcgt taaatatcaa attaacactc
     8041 cgggaatacg cagatcatca aaaagcaatg gacgcgctgg aagacggtga agttgatata
     8101 gtgttatcac atttagttgc ttcgccgcct cttaatgatg acattgctgc aactaatcct
     8161 ctgataatta cctttccggc gctggtcact acccttcacg attcaatgcg accgcttacc
     8221 tcatcaaaac cagtaaatat tgctcgagta gcaaattatc ccccagacga ggtaattcat
     8281 caatcatttc caaaagcaac aattatctct tttacaaatt tatatcaggc attagcatcc
     8341 gtctcagccg gacagaatga ttactttatt ggtagtaaca tcattaccag cagtatgatt
     8401 tcccgttatt ttactcactc cttaaatgta gtgaagtatt ataactcacc gcgtcaatat
     8461 aactttttat taaccagaaa agattcaatc gttcttaatg aagtactcaa tcgatttgtt
     8521 gatgctttaa caaatgaagt tcgctatgaa gtatcacaaa attggcttga tacaggaaac
     8581 ctggcctttc tgaacaaacc attagaactc actgaacatg aaaaacagtg gattaagcag
     8641 catcccgatt taaaggtgct ggaaaatcct tactcgccac cctattctat gacagatgaa
     8701 actggctcag ttcggggcgt gatgggtgat attcttaata ttattacctt gcaaacaggt
     8761 ttaaattttt ctccgatcac cgtttcacac aatattcatg ctgggacaca gcttaacccc
     8821 ggtggatggg atatattgcc cgccgctatt tatagtgaag atcgagaaaa taatgtttca
     8881 tttgctgaag tcttcataac aacgccttac gtttttgtca tgcaaaaagc gcctgacagt
     8941 gaacaaacat taaaaaaagg aatgaaagtt gccattccat attattatga gcttcattcg
     9001 caattaaaag agatgtatcc ggaggtagag tggataaaag tcgataacgc cagcgctgca
     9061 tttcacaagg tcaaggaagg tgaacttgat gctctggtcg cgacacagtt aaattcgcgt
     9121 tacatgatcg accattacta tcctaatgaa ctttatcatt ttcttattcc cggcgttcag
     9181 aatgcatcac tttcgttcgc ttttcctcgc ggagaaccgg aacttaagga tattattaat
     9241 aaagcactga atgcaattcc cccaagcgaa gttctgcgcc tgaccgaaaa atggattaaa
     9301 atgcccaatg tgaccattga cacatgggac ctctatagcg agcaatttta tattgttacg
     9361 acattatccg ttttattagt tggcagtagc cttttatggg gattctacct gttacgctca
     9421 gttcgtcgtc gtaaagttat tcagggtgat ttagaaaacc aaatatcatt ccggaaagcg
     9481 ctctcggatt ccttacctaa tccaacttat gttgtaaact ggcaaggtaa tgtcattagt
     9541 cacaatagtg catttgaaca ttatttcact gctgattact ataaaaatgc aatgttacca
     9601 ttagaaaaca gtgaatcccc ctttaaagat gttttttcta atacgcatga agtcacagca
     9661 gaaacgaaag aaaaccgaaa aatatacaca caggtatttg aaattgataa tggcatcgag
     9721 aaaagatgca ttaatcactg gcatacctta tgtaatctgc cagcaagcga acatg
//
LOCUS       DAPOXO010000141         9175 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.141, whole genome shotgun sequence.
ACCESSION   DAPOXO010000141 DAPOXO010000000
VERSION     DAPOXO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9175
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.141"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(1..105)
                     /locus_tag="ROH59_004682"
                     /pseudo
     CDS             complement(1..105)
                     /locus_tag="ROH59_004682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453335.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
     gene            849..1055
                     /locus_tag="ROH59_004683"
     CDS             849..1055
                     /locus_tag="ROH59_004683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4807074.1"
                     /translation="MTTPVSLMDDQMVDMAFITQLNGLTDKWFYRLIRDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARIAQPRP"
     gene            1151..1753
                     /locus_tag="ROH59_004684"
     CDS             1151..1753
                     /locus_tag="ROH59_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807075.1"
                     /translation="MKQQYQTRYELLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRATPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLEDWKENLKRK
                     SEKELEEWIINRQRQSAALTDLMDQYVLLAYRTTVDDNRN"
     gene            2954..3871
                     /locus_tag="ROH59_004685"
     CDS             2954..3871
                     /locus_tag="ROH59_004685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807076.1"
                     /translation="MVQKILSDKVMNERTNAYYSYYLGERNISVLPLNVYDPPERFIA
                     YIKKNRENLNITLSDFELEQIISGMRLKALAFLVPLEKISWIAGSERACLFSWYLLMQ
                     FIQNNRAKISADLLQKNKLYLKEEYLEGNAFPSDSSTQFRQILRVLDILSDKNLRDEW
                     IIQTKDRWIRAFKSKSPFSYLLPENEHECIWTWNYLKGKNIALEKLASFPGSADIYHA
                     IHLSFDIWVTCPLTSPDDIKNFRNSFNKAKAQRKYKKMQEDKVNVQFFLDAETRAQLK
                     ELSRVRRLSTGEMLHDLIVEEYKRYRHSR"
     gene            3956..4828
                     /locus_tag="ROH59_004686"
     CDS             3956..4828
                     /locus_tag="ROH59_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDX4807077.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMVITDLPGVGESRNRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCIASVARTVLRAVRDT
                     VVSVARAVWNWIFF"
     gene            5201..8047
                     /gene="ag43"
                     /locus_tag="ROH59_004687"
     CDS             5201..8047
                     /gene="ag43"
                     /locus_tag="ROH59_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDX4807078.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAA
                     VTSVPALAADTVVQAGETVNDGTLTNHDNQIVLGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATGTVINEKGWQAVKSGAMATDTVVNTGAEGGPDADNGDTGQFVRGNAVRTTINK
                     NGRQIVAAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQ
                     IVKEGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAATVTGSNRLGNFTVE
                     NGNADGVVLESGGRLDVLEGHSAQNTLVDDGGILAVSAGGKATDVTMTSGGALIADSG
                     ATVEGTNASGKFSIDGISGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGN
                     LSGRTQLSKGASMVLNGDVVSTGDIVNAGEIRFDNQTTPDAALSRAVAKGDSPVTFHK
                     LTTSNLTGQGGTINMRVRLDGSNTSDQLVINGGQATGKTWLAFTNVGNSNLGVATSGQ
                     GIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTS
                     MLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSY
                     GFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNL
                     VHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQL
                     QYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMSFGEGTSSRDTLRDSAK
                     HSVSELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARI
                     RENITLGVQGGYAHSVSGSSAEGYNGQATLNVTF"
     gene            8118..8276
                     /locus_tag="ROH59_004688"
     CDS             8118..8276
                     /locus_tag="ROH59_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDX4807079.1"
                     /translation="MPGCTSRLLPEGPFSREQAVAVKTAYRNVFTEDDQGTYSRLVIR
                     NAEGQLRW"
     gene            8431..>9175
                     /locus_tag="ROH59_004689"
     CDS             8431..>9175
                     /locus_tag="ROH59_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDX4807080.1"
                     /translation="MRLASRFGYTNQIRRDRPLTHEELMHYVPSIFGEDRHTSRSKRY
                     AYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSPGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPTRQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIH"
BASE COUNT         2239 a         2384 c         2393 g         2159 t
ORIGIN      
        1 gtcaacggca gagttaaagg cttccagctc cgcaggggta agtttataac gcgtgtggga
       61 aatcactttt tccagcgtct cccgggatga acaacgacgg aactgctgtg gttttaactt
      121 ccattagcct ctcattactt tatgctgcgg ttaacaggat gctgtcagca taccgcacca
      181 gcctggcatt ctggtaccct ccccaaactc attactcccg tgccaccact taaccggtct
      241 ctcagactgt cactcaccag gtcggatacg tttaccgctc agacggatgc ttaatgcact
      301 ctgttcacgt gtgttgcagg tacgttttat atacgcaggt tatacgccag ctatcagaga
      361 tagccctgtg ggtacaacgc aatctgctgc tactgcgttc tcatgcccac tgatcgcact
      421 cacagtgttt atttcacata tatgaactca tgtatttgat ctcatgtgtt tgatctctct
      481 tatatattta taataccaat cagacagtct tatcccacca gtgataactg tcgcctgccc
      541 acaggtcaca ggctgatata ccacaaccgc cttcaaaaac aactctgcaa ttatcagaac
      601 gctagttttc cccttgtctc acgaaagtcc tccctccttt atcgcgtgcg cgtgcggaag
      661 catcgtttcg caacaaccac ccgacatacc ggtacggctc agccaccgca atccccccgt
      721 ttatctcctg acggtcacat tcccgattat tttttacgtt tctccccggt tgttatgccg
      781 gtgaaggtgg tgcgttgttt tcatcaccaa cgccggttga gattaacaac atccggagga
      841 acattctcat gaccacccca gtttcactga tggatgacca gatggtcgac atggcattta
      901 tcactcaact gaacggcctg acagataagt ggttttacag gctcatcagg gatggggcct
      961 ttccggctcc catcaagctg ggccgcagct cccgctggct gaaaagtgaa gtggaagcct
     1021 ggctacaggc gcgtattgca cagccccgcc cgtaatttct gaccgttatc cgttcacccg
     1081 cagcagacgt aatccccggc ctgccggcgg cattctgctg cctgttatat cccccgtgag
     1141 gaatatgaaa atgaaacaac agtatcagac ccgttacgaa ctgctccacg aaagctacca
     1201 gaaatggctg accggcttca cccggcacgc cgtatcctgg ggcgtgtgtc atccgaatat
     1261 ctactacttc cataatctga cgcccgggtg ggtgtcattc aatggtgaaa aaccggagat
     1321 tgccatcgta ccccagagcc tgcaccggct gatttatggc cctgacaaac gggccacgcc
     1381 gcccctggat gatgatctga tagtgaattt atgcaccagt gaacatctgc tggttcatca
     1441 tccgatgctg gaaggcattc tcctgtctga atgtgaacgt ctgaggcagc gttctctggc
     1501 aaataaactg attagcctct tccgtcagtt tggtggcacg gagttgcgcc tcaaactggt
     1561 ctggctttgc tggcttgatt taatgaccgg aaacagcctt gaagactgga aagagaacct
     1621 gaaacggaaa tcagaaaaag agctggagga atggatcatc aaccgtcaga ggcagagcgc
     1681 agcactgacg gatctgatgg atcagtacgt gctcctggca taccgcacaa cggttgacga
     1741 taaccgcaac tgatgccggt tgcttccgga aggtgtgaca aaatacggaa atgatgatgc
     1801 tcccggcccc gcatgctcac ctgcagagcg tgttcgtcgt catcatactg agccatgacg
     1861 ggcgtcttaa gggcatcctg tcattgctga gcaggcaaca ccaccagagg agccacggac
     1921 agggatgttc tttacagccc gatgcacgcc aggttctcag cagactgaat gtgcaggtgc
     1981 ggttattcac cagaaatggc atgctgcggt acatacccat cctggtgaca atatgtacgt
     2041 ggcgacagcg atcccggcac tgtggaagag actcactcag cctgcaggat attctttccg
     2101 gcatccggga atgtccgcct gaatgcaaac aggatgatat ttgaatccgt aatactgttc
     2161 tttcatcata aataatttat gcagatacag ttaaccgtca cagtagcagg tttgttttcc
     2221 cgggaaataa tatccgtcag actgatgccg gaacatatct gaaacacgtt atgatgtttt
     2281 gttatcagaa atgttgtata ttcttatccg tggcgacagt ttaatgccct ctggtatcac
     2341 ctgataatgc atatcctgcg atgattcgtt atatttacgg gacacgcctc ttttcattgt
     2401 gctccttttc agacttcatt ttccgtaagt gttccccggc ataaaggagg tacctttctg
     2461 gcgtttataa ctctctttat cggtgacgcc ggtaatacag ggaataccac accgacaaac
     2521 gaggtattaa cagacgatat ttcagtgtcc ataatttttc tgtccggtta aataacgtca
     2581 gtctgctgcc ctctgactgt aatcatcaaa gccggaatgc ataccgggtt acaacgtaaa
     2641 aaaagtgatg ctggcccccg gtgcagctgg cgggcgaaac atgtttacct ttcaataccc
     2701 cctgtctgca gtctccactc ttccatcctc ttaagctacg tcggccacat gagtgcactt
     2761 ccatgataac aggtattcct gtcagcataa cgaagccggt taccttccct tcctcctgca
     2821 tttcctgtca gaatgactgt acagcgcgca gattgccttt ttattgacca ccttaatata
     2881 ctattataaa cttcttttta tcatgttatt atcaccttat tatgtttaat ttttaagcaa
     2941 ccggagaaag aggatggttc agaaaatttt gtcggataag gttatgaatg aaagaacaaa
     3001 tgcgtattac tcttattatc ttggagagcg taatatctcc gtactgcccc ttaatgttta
     3061 tgatcccccg gaacgtttta tcgcttacat aaaaaaaaac agagaaaatc tgaacatcac
     3121 actttcagat tttgaacttg aacaaataat ttctggtatg cgtctgaagg ccctggcctt
     3181 cctggtcccc ctggaaaaaa tatcctggat cgcgggcagt gaacgcgcat gcttattttc
     3241 ctggtatctg ttgatgcagt ttatccagaa taacagggca aaaataagcg cagacttgct
     3301 tcaaaagaat aaactgtatc ttaaagaaga gtatctggaa gggaatgcct tcccgtcgga
     3361 ctcatcgaca cagttcagac aaatactcag agttctcgat attctttctg ataagaattt
     3421 gcgggatgag tggataatcc agaccaaaga cagatggata cgggcattta aatcaaagag
     3481 tcctttcagt tacctcctcc cggagaacga acatgaatgc atatggacat ggaattattt
     3541 gaagggaaaa aatattgcac tggaaaaact ggccagtttt cctggttctg ctgatattta
     3601 ccacgcaatc cacctttcat ttgacatatg ggttacctgt ccactcacct cacctgacga
     3661 tataaaaaat ttcagaaaca gtttcaataa ggccaaggcg cagcgcaagt acaaaaaaat
     3721 gcaggaagat aaagtcaatg tacagttttt tcttgacgca gaaaccaggg cgcagctcaa
     3781 agaattatcg agggtcagaa gactcagtac cggcgaaatg ctgcatgacc tgattgttga
     3841 agagtataaa aggtaccgac attccagata atttcagaca tatattatct ccgtgagtcc
     3901 cccgccacct ttccggtgtg cgggggtttt gtcttttttc accgggaata catgtatgaa
     3961 tccgtctgat gccattgagg caattgaaaa accgctctcc tccctgcctt actcgctttc
     4021 ccgtcacatc ctggaacatc tgcgcaaact caccagtcac gaacccgtga ttggcattat
     4081 gggtaaaagc ggggccggta aatcctcact ctgtaatgca ctgtttcagg gggaggtcac
     4141 cccggtcagt gatgttcacg ccggcacccg ggaagtacgg cgcttccgtc tgagtggcca
     4201 tggtcacagc atggttatca ctgacctgcc cggggtgggc gagagccgga acagggatgc
     4261 agagtatgaa gccctgtacc gtgacattct gcctgaactt gacctggtac tgtggctgat
     4321 taaagccgat gaccgtgccc tgtctgtgga tgagtatttc tggcgacaca tcctgcaccg
     4381 gggacatcag caggtgctgt ttgtggtgac gcaggccgac aaaacggagc cctgccatga
     4441 atgggatatg gccggcattc agccttctcc cgcacaggca cagaacattc gggagaaaac
     4501 ggaggcggta ttccgtctgt tccggcccgt acatccggtt gtggccgtat cggcccgcac
     4561 cggctgggaa ctggatacgc tggtcagtgc gctcatgaca gcacttcccg accatgccgc
     4621 cagtcccctg atgacccgcc tgcaggacga gctgcgcacg gaatctgtcc ggtctcaggc
     4681 ccgtgaacag tttaccggtg cggtggaccg gatatttgac acggcggaga gcgtctgtat
     4741 tgcctctgtt gcacgcacgg ttctgcgtgc cgtccgtgac acggtggtct ctgttgcccg
     4801 cgctgtatgg aactggattt tcttctgaac actctgccag gggaaatgcc tgattacatt
     4861 gcgttaacca actgaaaaca tgatacaaac actccatccc cctcctgttt ctcttgcgtg
     4921 actgctctgc tgttaataga ataaaacgat cgataaaaca ggtatcgatc gttaccatcg
     4981 atcgtttata gtggttaatg gtctgcgaaa aggcagctga atctcttcat catgcagaac
     5041 ggaattgcac acaacggact gatacttctc tggcggatga gagaggggaa gcatttatgt
     5101 ccgggaaaaa ccactttatc tgaccatgct gttttgtacc tgccggtatc cacttttgtg
     5161 ggtaccggct tttttattca ccctctgtaa ggaaaagctg atgaaacgac atctgaacac
     5221 cagctacagg ctggtatgga atcacattac gggcaccctg gtggtggcct ccgaactggc
     5281 ccgctcacgg ggaaaacgcg ccggtgtggc ggttgcactg tctcttgctg ctgtcacatc
     5341 agtcccggca ctggctgctg acacggttgt acaggcggga gaaaccgtga acgacggaac
     5401 actgacaaat catgacaacc agattgtcct cggtacggcc aacggaatga ccatcagtac
     5461 cgggctggag tatgggccgg ataacgaggc caataccggc ggacaatgga tacaaaatgg
     5521 cggtatcgcc aacaacacta ctgtcaccgg tggtggtctt cagagagtga atgccggagg
     5581 aagcgtttca gacacggtta tcagtgccgg aggaggacag agccttcagg ggcaggcagt
     5641 gaataccact ctgaacggcg gtgagcagtg ggtacatgaa ggcgggattg caacgggtac
     5701 cgtcattaat gagaagggct ggcaggccgt caaatccggc gcaatggcaa ccgacacggt
     5761 tgtgaatacc ggcgcggaag ggggaccaga tgcagacaat ggtgataccg ggcagtttgt
     5821 tcgcggaaat gccgtacgta ccaccatcaa taaaaatggt cgtcagattg tggctgctga
     5881 aggaacagca aataccactg tggtttatgc cggcggcgac cagacggtac acgggcatgc
     5941 gctggatacc acactgaatg gcggttacca gtatgtgcac aacggaggca cagcctctga
     6001 cacggttgta aacagtgacg gctggcagat tgtcaaggaa ggtggtctgg cggatttcac
     6061 caccgttaac cagaaaggca aactgcaggt gaacgccggt ggtacagcca cgaatgtcac
     6121 cctgaagcag ggaggcgcac tggtcaccag tacggcggca accgtcaccg gcagcaaccg
     6181 tctgggcaat ttcactgtgg aaaacggtaa tgctgacggt gttgttctgg agtccggtgg
     6241 tcgcctggat gtactggaag gccattcagc gcagaatacc ctggtggatg acggcggtat
     6301 cctggcagtg tctgccggtg gtaaggcaac agatgtcacc atgacatccg gtggtgccct
     6361 gatagcagac agtggtgcca ctgttgaggg gaccaatgcc agcggtaagt tcagtattga
     6421 tggtatctcc ggtcaggcca gcggcctgct gctggaaaat ggcggcagct ttacggttaa
     6481 tgccggagga caggctggca acaccactgt cggacatcgt ggaacactga cgctggctgc
     6541 cgggggaaat ctgagtggca gaacacagct cagtaaaggt gccagcatgg tactgaatgg
     6601 tgatgtggtc agtaccggcg atattgttaa cgcaggggag attcgctttg ataatcagac
     6661 gacaccggat gccgcgctga gccgtgctgt tgcaaaaggc gactccccgg taacgttcca
     6721 taaactgacc accagtaacc tcaccggtca gggtggcacc atcaatatgc gtgttcgcct
     6781 tgatggcagc aatacctctg accagctggt gattaatggt ggtcaggcaa ccggcaaaac
     6841 ctggcttgcg tttacaaatg tcggaaacag taaccttggg gtggcaacct ccggacaggg
     6901 tatccgggtt gtggatgcac agaatggcgc caccacagaa gaaggtgcgt ttgccctgag
     6961 tcgcccgctt caggccggcg cctttaacta caccctgaac cgtgacagcg atgaagactg
     7021 gtacctgcgc agtgaaaatg cttatcgtgc tgaagtcccc ctgtatacat ccatgctgac
     7081 acaggcaatg gactatgacc ggattctggc aggctcccgc agccatcaga ccggtgtaaa
     7141 cggtgaaaat aacagcgtcc gtctcagcat tcagggcggt catctcggtc acgataacaa
     7201 cggcggtatt gcccgtggag ccacgccgga aagcagcggc agctatggct tcgtccgtct
     7261 ggagggtgac ctgctcagaa cagaggttgc cggtatgtct ctgacgacag gggtgtatgg
     7321 tgccgcaggc cattcttccg ttgatgttaa ggatgatgac ggctcccgcg ccggcacggt
     7381 ccgggatgat gccggcagtc tgggcggata cctgaatctg gtacacacat cctccggcct
     7441 gtgggctgac attgtggccc agggaacccg tcacagcatg aaagcgtcat cggacaataa
     7501 cgacttccgc gcccggggct ggggctggct gggctcactg gaaaccggtc tgcccttcag
     7561 tatcactgac aatctgatgc tggagccaca actgcagtac acctggcagg gactctccct
     7621 ggatgacggc caggataacg ccggttatgt gaagttcggg catggcagtg cacaacatgt
     7681 gcgtgccggt ttccgtctgg gcagccacaa cgatatgagc tttggtgaag gcacctcatc
     7741 ccgtgacacc ctgcgcgaca gtgcaaaaca cagtgtgagt gaactgccgg tgaactggtg
     7801 ggtacagcct tctgttatcc gcaccttcag ctcccggggt gacatgagca tggggacagc
     7861 cgcagccggc agtaacatga cgttctcacc gtcccggaat ggcacgtcac tggacctgca
     7921 ggccggactg gaagcccgta tccgggaaaa tatcaccctg ggcgttcagg gcggttatgc
     7981 ccacagcgtc agcggcagca gcgctgaagg ttataacggt caggccacgc tgaatgtgac
     8041 tttctgataa tcaggtcact ctccttcagg ccccggtcat catgaccggg gctttttact
     8101 ttcagggagc aacagatatg ccgggttgta catcacgttt attgcccgaa ggccctttct
     8161 cacgcgaaca ggctgttgcc gtcaaaacag cttaccgcaa tgtgtttact gaagatgacc
     8221 agggaacata ttcccggctg gttatccgta atgctgaagg tcagttgcgc tggtgatgcc
     8281 ggaacacagc ttaatactca gctcgccagt taagggcttc tcagacaata aacgtcattc
     8341 atttcatctg tcaggccgcg tcttctccgg gagacgtggc tttttcattt attacaccag
     8401 taaatcttaa ccaccgataa ggagcaaatt atgcgactag ccagtcgttt tggttatacg
     8461 aaccagatac gccgtgaccg tccgctgaca cacgaagaac tgatgcacta tgttcccagt
     8521 attttcggtg aagaccggca tacttcccgc agtaaacgat atgcgtacat tcccaccatc
     8581 accgtactgg aaagcctgca gcgggaaggc tttcagccat tcttcgcctg ccagacccgt
     8641 gtgcgcgacc cgggccgccg gggatacaca aaacacatgc tgcgtctgcg gcgggccgga
     8701 gagataaacg gagaacatgt ccctgaaatc attctgctca actcccatga cggtacctcc
     8761 agctaccaga tgctgccggg ttacttcagg ttcgtctgtc agaacggatg cgtctgtggt
     8821 cagtctccgg gggaagtgcg tgttccgcat cggggaaatg tggtggacag agtcattgaa
     8881 ggggcttacg aggtggtggg cgtgtttgac cggattgagg aaaagcgtga tgccatgcag
     8941 tcgctggtcc tgccgccacc gacacgccag gcgctggcac aggcggcact gacttaccgt
     9001 tatggtgacg aacatcagcc agtcaccacc gctgacattc tgacaccacg acgccgggag
     9061 gattacggta aagacctgtg gagcgcatat cagaccatcc aggagaatat gctgaaaggc
     9121 ggaatttccg gccgcagtgc aaaaggaaaa cgtatccaca cccgtgccat tcaca
//
LOCUS       DAPOXO010000142         8967 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPOXO010000142 DAPOXO010000000
VERSION     DAPOXO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8967
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.142"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1428)
                     /gene="fadK"
                     /locus_tag="ROH59_004690"
     CDS             complement(<1..1428)
                     /gene="fadK"
                     /locus_tag="ROH59_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HDX4807081.1"
                     /translation="MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVV
                     DNHGATYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKTGAVS
                     VPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
                     APATSSLSLSQILADNTPLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASER
                     AYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQ
                     RCTCMLGATPFVYDLLNLLEKQPADLSALRFFLCGGTTIPKKVARECQQRGIKLLSVY
                     GSTESSPHAVVNLDDPLPRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNV
                     FMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVE
                     DILLQHPKIHDACVVAMPDERLGERS"
     gene            complement(1485..1778)
                     /locus_tag="ROH59_004691"
     CDS             complement(1485..1778)
                     /locus_tag="ROH59_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HDX4807082.1"
                     /translation="MSQNATVNVDIKLGVDKFHVDEGHPHIILAANPDINEFRKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWQYPAGTFGIEFRYG"
     gene            complement(1775..3064)
                     /locus_tag="ROH59_004692"
     CDS             complement(1775..3064)
                     /locus_tag="ROH59_004692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDX4807083.1"
                     /translation="MSDDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAASAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVSASNPHHYAVGVKEVIGLTPEQINDRFNVTGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSVSLGLVCGLGDIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SAHMVPEGGLAMVPQLVNDGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KERADFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNDMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(3119..4057)
                     /locus_tag="ROH59_004693"
     CDS             complement(3119..4057)
                     /locus_tag="ROH59_004693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HDX4807084.1"
                     /translation="MSQLNSVWVFSDNPERYAELFGSAQQWGQQVYAIVQNTEQAQAV
                     MPYGPKCIYVLEQNDALQRTENYAESIAALLKDKHPAMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIVDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTRDISH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLNR"
     gene            complement(4077..4841)
                     /locus_tag="ROH59_004694"
     CDS             complement(4077..4841)
                     /locus_tag="ROH59_004694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HDX4807085.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHSLYMVQDAQLEHALPLDTAKALA
                     TAVEKIGFDLLIFGEGSGDLYAQQVGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIGWSQSAPLAEL
                     TGIRVPPQTERKHIILDNDSPEAIAELAEHLKKALN"
     gene            5157..6068
                     /locus_tag="ROH59_004695"
     CDS             5157..6068
                     /locus_tag="ROH59_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDX4807086.1"
                     /translation="MYQRCFDNASETLFVAGKTPRLSRFAFSDDPKWESGHHVHDNET
                     ELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHAVASDVNDPATTCTCALYGFQFQ
                     GAEENQLLQPHSCPVIAAGQGKEVIKTLFNELSVILPQSKNSQTSSLWDAFAYTLAIL
                     YYENFKNAYRSEQGYIKKDVLIKDILFYLNNNYREKITLEQLSKKFRASVSYICHEFT
                     KEYRISPINYVIQRRMTEAKWSLTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPS
                     DYRRQFKNCFAEQEILSEFPQPVSLAG"
     gene            complement(6111..7262)
                     /locus_tag="ROH59_004696"
     CDS             complement(6111..7262)
                     /locus_tag="ROH59_004696"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDX4807087.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(7276..8871)
                     /locus_tag="ROH59_004697"
     CDS             complement(7276..8871)
                     /locus_tag="ROH59_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDX4807088.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SDLAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIVFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
BASE COUNT         2186 a         2318 c         2169 g         2294 t
ORIGIN      
        1 tgaacgttca cctaaacgtt catcgggcat cgcaaccaca caggcatcgt gaattttagg
       61 atgctgcaat aaaatatctt ctacttcacg gctgctaata ttttcgccgc cgcggacaat
      121 aatatctttc ttgcgcccgg ttatttttat atagccagcc tcatccatgc ggcagagatc
      181 gccgctgtaa taccagcctt cttcatccag cgcacgggcg gttaattcag gttcatcaaa
      241 ataccccata aacacattgg ggccacgcga ggcttcttca ccttcgcaac ctggcggtaa
      301 agtcttgcgt gcgtcatcga ccactttaat ctctacacct gcggcagcgt aaccgtcggt
      361 gtgcataaag cgcggcaaag gatcgtcgag attcaccacc gcatgcggcg aactttctgt
      421 ggaaccataa acacttaata atttaatgcc gcgctgctgg cattctcgcg ccactttttt
      481 ggggattgtg gtacctccgc aaagaaagaa gcgcagcgct gaaaggtctg cgggttgttt
      541 ctctagtaaa ttcaaaagat catagacaaa cggcgttgcg ccgagcatac aggtgcaacg
      601 ctgctgctca agcagcgcga gacacgcatc aggagtgaaa atatctaaca acacgctgcg
      661 agcaccaatc aaaaaaggtg ctgttacgcc atgcagaaag cccgttgcgt gaccaagtgg
      721 cgcaggcatc ataaagacat cctgccaggt cagatttagc cgcgcgcaat aagcccgctc
      781 actggcgaga atattgttat gcgttagcat cacacccttt ggcagaccct cggttccgga
      841 ggtaaatagc acagcggcta attcatcgcc gtgggtcgtt atcgccgtgg tcagaggagt
      901 attgtcggcg agaatctgac ttaatgagag ggaagaggtg gcgggagcca gtttgtccac
      961 gccgacaatt tgttgtagtt gtggaagctg attttgcagc ggcaggatta aatctaccgg
     1021 acgcgtttgt ttaaacaacg tcggtgcaaa gaacattttt gcctgacact tattgagcac
     1081 ccacaccagt tctgcttccc gccaggaagg taacagcggc acggaaaccg caccggtttt
     1141 caggcaggca agatagataa cggtaaattc acaccagcct ggcagttgaa atgcgatgcg
     1201 atcgcctgat tcaataccct tcgctaacat ccagtttgcc agacagctcg cggcgtgatc
     1261 gagcgcgcta taggtgtacg ttgcaccatg attatcgacc acggcaattt tgtctggcat
     1321 cgcacgagcg gtctgctgcc agtaatcggc cagcgaagca tcgccccata acccttgctg
     1381 acgatacgcc gcacgacgtt gttcgttgaa cgttaatgtc actttcattt tggactctcg
     1441 aaacagaaca tcaggcccga gatgcgggcc tgtgggatgc atgattagcc gtagcgaaat
     1501 tcaataccga aggtgcctgc gggatattgc cactgttcga gaatagtgtt gccgcacagc
     1561 acccgacagg tgccgcactc cagacaaccg gcggaatcga aatgaatgtt tcctgcgtca
     1621 tcctgcttat aaagtccggc agggcaagct ttcattaatt tacggaattc attgatatcg
     1681 ggatttgccg ccaaaatgat atgcgggtgg ccctcatcaa catggaattt atcgacgcct
     1741 aatttgatgt cgacgttaac cgtagcgttc tggctcatag cgcggttgct cccttaatgc
     1801 catctttcag caagttgatc agcccaattt tcttcgcgtg tcccatgatc attttgcgta
     1861 ccggctggtt tggtttgccg tcaatggtga acatatcgtt catgatgtcg gcgaccattc
     1921 gtgggtattg gctaaacagg cgcgggtttt ccatcagcgc cgggatcttg cggaaatgct
     1981 gcatatcgcg cataacacaa ctttgttcca gctcacgttt gtattgcgcc agactgctgg
     2041 cggagaaatc cgcgcgttct ttggcggcga tcaccgttgt ggcggcagcc tgagctgatg
     2101 caatggctaa atccatgccg cgaactgtaa aacccaaatt caggcagaag cctgcggcgt
     2161 caccaacgat catcacgcca tcgttaacca gctgcggcac cattgccaga ccgccctccg
     2221 gcaccatatg cgcggaatat tcaagcagtt tgccgccgct aatcagcggg cgaatagcgg
     2281 ggtgttgttt aaaatcttcc agcatttgcg gcacgctttt ttgcgcatgg gcgatatcac
     2341 ccaatccaca aaccagcccc aacgatacgg aatccttgtt ggtatagagg aatccgccgc
     2401 ccatcaggcc gtcagaaggg gaaccggcaa acagccaggc ggcaccttcc tcgcccgtaa
     2461 cattaaagcg atcgttgatc tgttctggtg tcaggcctat aacctcttta acaccaacag
     2521 cgtaatgatg cggattggaa gcggaaacca ttcccagcga gcggccaagc atcgagttaa
     2581 cgccatcagc cagaatcacc acattcgctt cgagaatatc atccccggcc tggacgccag
     2641 tgaccttgtt tccttcacga accagcgcat cgacgcgtac gcccgggata aactgcgcgc
     2701 ccgcctgctc ggcttgttcc atcaaccacg ggtccagacg attacgcaat acggtataag
     2761 acgcgtgttg cggaacatct ggttgctcgc ggtgaaaatc gagggtaacg gcgctttctt
     2821 cggttaagaa ggagattttc tcgcgtgtga ccttgcgttc taccggcgct gatgctgcaa
     2881 agcctggaat aattgcttca agtgtgtggg cataaagacg cccgccggtc atgtttttac
     2941 atccggcact gtcgccgcgt tctatcacca ggacatccag cccggctcgc gccatgacca
     3001 gtgcggcaac gctaccggca acgcccgcac cgaccacaat ggcatcaaat ttgtcatccg
     3061 acatgcgtta tgctcccttc ccgctgcgtt tacagcggga gatgtggttg aaagggaatt
     3121 agcgattcaa ctggctaatc agggcaggga cgactttgta gatatcgccc accagaccgt
     3181 agtcggcata gttgaagatt ggcgcatttt tatctttatt aatggcgaca atcacttttg
     3241 cgccgttgcc gccaaccata tgctggatct gcccggagat ccccagcgtc aggtagagat
     3301 cggatttcag caacacgccg gagacaccga tataacgttc acgctccatc cagttctcgc
     3361 cttcggcaat tggacgtgaa cagccgactt cagcattcag cactgccgcc agttcgtgga
     3421 ccattttcag gtcatcctgc gccgccagac cacgaccgac gccaaccaca cgttttgctt
     3481 tgctcaggtc cacgctgctt gccgctttcg cacggcgttc gcgacagaga atttcatgac
     3541 gcggggcaac ataaggtacc gtttctgtcg ggcactgatg agagatatca cgggtgcacg
     3601 gttcctgaac accgggtgca agggtaatga tcgccagcgg gctgttgatc ttttcctgag
     3661 cgaacgctaa cccgccatac atccggtgtt cggcgcaaat gtgaccatcg acaatatcca
     3721 ccgccgtggc atcgttcacc agcgccgcat tcagttgcac acttaaccgt gcggccagag
     3781 ctttaccacg tttcgtcgcg gccaacagca acatagcggg gtgtttatct ttcagcaggg
     3841 cagcaatgct ttcggcgtaa ttttcagtac gttgcagcgc gtcgttttgc tcaagaacat
     3901 aaatgcattt tggcccataa ggcataactg cctgcgcctg ctcggtattt tgtacaatgg
     3961 catacacctg ttggccccat tgctgagcgc tgccaaacag ttcagcataa cgttcaggat
     4021 tatcgctaaa gacccagacg ctgtttaatt gactcatcgt ttcttctccg taggcttcag
     4081 ttcagggctt tcttcagatg ttccgccagc tcggcaatgg cctccggcga atcgttatcg
     4141 agaatgatgt gcttacgttc tgtttgcggc ggtacgcgaa tgccggtcag ttcagcaagt
     4201 ggtgcgctct ggctccagcc aatatcactt gcctgccact gatttaccgg ttttttaccc
     4261 gcgccgagaa tggctttcat cgaaggaata cgtggcacgt taatatcgga ggtgacgcag
     4321 agcacggctg gaacagagag ttcaataact tcaacatcat cttcaagcgt gcgttcaatc
     4381 accagtgtat tgccctgacg ctgaatagca ctcactgcat taatcaccgg aagttgcaga
     4441 atttctccga ccagcaagcc aacctgctgg gcataaaggt cgccggaacc ttcaccaaag
     4501 atcagtaaat cgaagccgat cttttcaact gctgtcgcca gcgcctttgc ggtatcgaga
     4561 ggcagtgcat gctcaagttg tgcatcctgc accatataca ggctgtgcgg cccgcgggat
     4621 agcacgtctt tgcgcacttt cgagttctgc aacaaagagc cgccgacggt cagcgcggct
     4681 atctcatcgt catctgttgc aagctggctt gcagcttcaa tggcattgag atcgaactgg
     4741 ctgattttgg cgtcggcatt gtcgaaattc agggtgtatt ctggagtgac aacaatgtcc
     4801 tgttcttcag gcaccagctt aaagcaggtt attattttca tgatttctcc tgtgagtcgc
     4861 atacggaacc atctccgatg gaaagtaaaa atggcctgaa aatagtgtgc gatagcggtg
     4921 cggggttttc gacggagcaa gctgttttcc ttgccaacaa tcttgcaaaa aaaatgcgat
     4981 cgctaaaaca aaagtgcaat ttgcggcaat atagttattc catgaccgta ctatcttgca
     5041 ttcagtgtaa ataatcttgt ttagctctcg ctaaacgcgg ttgtataacc gcaatacacg
     5101 ccgtatttta tccggcatat attgtttttg cttgctcatg gaatagggag gttgtcatgt
     5161 atcaacgctg ttttgataat gccagtgaaa cgctgtttgt cgccggtaaa acgccacggc
     5221 tttcacgttt cgcatttagc gatgatccaa aatgggagtc tggacatcac gttcatgaca
     5281 atgaaaccga gctgatttac gtcaagaaag gggtagcaag gtttaccatc gattcttcgt
     5341 tatatgtcgc gcatgccgat gacattgtgg tgatagaacg tggcaggttg catgcggtgg
     5401 cctctgacgt taacgatccg gcaacgacgt gtacctgtgc gctgtacggc tttcagtttc
     5461 agggggctga ggaaaatcag ctactgcaac cgcattcttg cccggtaatt gccgcaggac
     5521 agggaaaaga agtcattaaa accttattta atgagctaag tgtgattttg ccgcaaagta
     5581 aaaatagcca aacatcttcg ttatgggacg catttgccta tacgttagca attctttact
     5641 acgaaaactt taaaaatgct tatcgttcgg agcagggata tattaaaaaa gatgttctga
     5701 taaaagatat tcttttctat ctgaataata actatcgcga aaaaatcact ttagagcagt
     5761 tatcgaaaaa atttcgtgcc agcgttagtt atatctgcca tgaatttacc aaagagtatc
     5821 gtatttcccc tattaactat gttattcaac ggcgtatgac ggaagcgaaa tggtcactca
     5881 ctaatactga attatcacag gcagagatct cctggcgtgt gggttatgaa aatgtcgatc
     5941 actttgccaa actgtttttg cgccatgtcg gctgttcgcc cagcgattac cgcaggcaat
     6001 ttaaaaactg ttttgcggaa caagaaatcc tatctgaatt tcctcaacca gtaagtcttg
     6061 ccggataaat ctggcggcgc agtttgttaa gaagctgcgc cgcctgcaga ttatttgttc
     6121 tgataatctt tcaggatctg ccgacctgct acgtaaatca taatttcgtc tgtaccgccg
     6181 ccgatacgtt cacaacggac atcacgccag aagcgggaga cgcgcgcctc atcggtatag
     6241 cccagaccgc ccatgatttg aatcgcatca tcaatgactt ccattgcggt acgtgcgcag
     6301 tacagttttg ccagcgccgc gctggtgcgc agtgactgat gctgatcggc ttgccatgcc
     6361 actttcaaca ccatgttgcg catgttgtcg atcttaatcg ccatcagcgc cagtttttcc
     6421 tggatcatct ggttatgacc aatgggctta ccaaaagcga tacgctggtt ggcatagcgg
     6481 gcggcatctt cgaatgcgca ttcggcaaag ccggtgctgc gcgcggcgtt gatcaggcgc
     6541 tccatctcaa agttgtacat cacattgagg aaacccattc cttcttcgcc caccatgtcg
     6601 ctctcttcaa cttccacgtt gtcgagatag acttcgcagg tgctgagcat atgccagccg
     6661 attttatgca gtggattgat tttaatgccg ggcttactgg agtcgaccca ccacagagta
     6721 aaggcctttt tcggatcttt cggttgcgga tcgcgcgcca acaccagcat atatggatac
     6781 tctttcgcac cggtaataaa ggttttctgt ccgttgatgt aaaccttgcc gtttttacgc
     6841 gtgtaagtgg tagtggcact gttgttgtct gagcctgcgc ctggctccgt caatgccagg
     6901 gcataggcgg gatcacccgt ttccagggtg ctctctgccg ttttacgtag ctgctctgca
     6961 gaaccgaaac ggcgcatact gtgaatacat tgaccgttgg taatcaaaaa tgccggagca
     7021 ccgcattttg acacttccat cagcgccagc atttgggtga cgtaatccgc agggatacca
     7081 ccaaattctt ccggcacgcc aagcatggaa ataccgttat ccgccagtgc ccgcataaac
     7141 tcacgcgggt atgtcccgtt ttgatcgcag gtgcggaaat actcttccgg aaagttagtc
     7201 gtaatcagtt cgcgaatact ggccagcagc agttcttgtt cttcagttaa agagaaatcc
     7261 atcattatac tcctgttaat gagccgcttc aggcaggaca aaacccatcg ccgcatcgat
     7321 aaataatctt tcgtccatca gtttgagttc tggcgaaatc actggggtga aatccatttt
     7381 gtcgagaata tctttttgta aatcgacgcc aggagcgatt tcgattaaat gcaggccgtc
     7441 ttcttttagc gtgaatacgg cgcgctcagt gatataacga acatccagcc ctcgctcgag
     7501 agcgattttt ccgctgaaag ttatttccgg tagttcccga ataaatttct tcacccgtcc
     7561 ttcctggacg atatttaatt tgccgtcggt aatttctgtt tttaaactgc ccgcagttaa
     7621 tgtgccgcag aaaacgattt tcttcgaagt ggcactgata tcaataaatc caccggtgcc
     7681 catgatttta ccattgaatt tatgcacgcc gacgttaccg tgctggtcga cttcagcaaa
     7741 actcaaataa caaacatcca gaccaccacc gtgataaaaa tcaaactggg acgtcatatc
     7801 cagaatggcg cgggtattca cgttcgcgcc aaaggcgatc ccctgtgaag taataccgcc
     7861 aatcggacct gtttctaccg tcagaataaa gtcatcagca caaccttctt cccgggcgac
     7921 caggccaatg ccgtcagcaa taccgacgcc gacattcccc actgcgcctt tgcgcatttc
     7981 gaataatgca cgccgtgcaa ctaatttacg ttggtttagg ggcaggctaa gtttggtgct
     8041 gtcatcaagg gtgaagtcac cagaaataaa gcggttaacc ggcgcaccgc catacagttg
     8101 ggtttgatcc ggatcgacca ccacaatatc caccagataa cccggaatac ggacagattt
     8161 aggatgcagc gtggctttct taaccatttt ctgcacctgc atcatcacaa taccgccgtt
     8221 attgtgcacc gcctgggcaa taaccaatgc gtcgagatac atcacctcat cttcaaaagt
     8281 ggcgtagcct tcgctgtcgc aggtggtagc gcgaatgaag gcgatatctg gcgcaatcgc
     8341 tttgtaatag agatattctt tgttatcaaa ctcgaccagt ttaatcaggt cttctttagt
     8401 gacttcattc agtttgccgc cttgctggcg tggatcgaca aatgttccga tgccaatatc
     8461 actaataata ccaggctggt gggctgcggc ggcgcgtaag gtttgtgtaa gtacaccttg
     8521 tggatagtta taagcaataa ttttattttg ttctgcgaga tcagaaatac gcggtgattg
     8581 tccccagtga ccgcataatg cccatttcac caggccttct tgcgccagcg gactaatacc
     8641 acggtcggcg cgatcgccaa gccctgttgg actaataatc gataaattac gtggtgtttg
     8701 agtctgttta tatttatcag caagagcagt aattaacgtg gtggcttcca gaataccgcc
     8761 gccagcgcct aacacacaaa gtgttgcttc gtcgggaata taattcaccg cttcctgtgc
     8821 cgataggacc ggcactcgtc cattaatacg aggtggtttt acaggtttca ttgttaattc
     8881 ctgattcagg tgtgattttc cctacgccag atggagaatt agcgcacaga gactcacgaa
     8941 atatttttat taaatacggt taaaaat
//
LOCUS       DAPOXO010000143         8621 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPOXO010000143 DAPOXO010000000
VERSION     DAPOXO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8621
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.143"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1047)
                     /locus_tag="ROH59_004698"
     CDS             complement(<1..1047)
                     /locus_tag="ROH59_004698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HDX4807089.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGIGPIFDYIPGG
                     IQKAENSGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKN"
     gene            complement(1217..2095)
                     /gene="glxR"
                     /locus_tag="ROH59_004699"
     CDS             complement(1217..2095)
                     /gene="glxR"
                     /locus_tag="ROH59_004699"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDX4807090.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTDASDIIFIMVPDTPQVEDVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     gene            complement(2195..2971)
                     /gene="hyi"
                     /locus_tag="ROH59_004700"
     CDS             complement(2195..2971)
                     /gene="hyi"
                     /locus_tag="ROH59_004700"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HDX4807091.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKQVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPTGFSSEQIHTTLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYEYLFTVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     gene            complement(2984..4765)
                     /gene="gcl"
                     /locus_tag="ROH59_004701"
     CDS             complement(2984..4765)
                     /gene="gcl"
                     /locus_tag="ROH59_004701"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HDX4807092.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAVLLQQFAELTSIPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPERNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKILMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAADAPTETCFMHYE"
     gene            complement(4855..5670)
                     /gene="allR"
                     /locus_tag="ROH59_004702"
     CDS             complement(4855..5670)
                     /gene="allR"
                     /locus_tag="ROH59_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HDX4807093.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDNQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHL"
     gene            complement(5748..6230)
                     /gene="allA"
                     /locus_tag="ROH59_004703"
     CDS             complement(5748..6230)
                     /gene="allA"
                     /locus_tag="ROH59_004703"
                     /EC_number="4.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HDX4807094.1"
                     /translation="MKLQVLPLSQKAFSAYGDVIETQKRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     gene            6460..7386
                     /gene="allS"
                     /locus_tag="ROH59_004704"
     CDS             6460..7386
                     /gene="allS"
                     /locus_tag="ROH59_004704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HDX4807095.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLCQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVARLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMLDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            7455..8561
                     /gene="mnmH"
                     /locus_tag="ROH59_004705"
     CDS             7455..8561
                     /gene="mnmH"
                     /locus_tag="ROH59_004705"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDX4807096.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMN
                     NDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQ
                     RSHIVQSWLHDAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENMLAAEMLKTDAHQDLRLWVLEDES
                     RMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKTYACGY"
BASE COUNT         2252 a         2268 c         2036 g         2065 t
ORIGIN      
        1 gtttttatag gtcagtttcg tcggtgcaat ggcggcaatc tgataaccag ccggaataat
       61 attaccggtg gcgttagtag agatagtcgt catcagaata accagtaccg caaagaacga
      121 ggcgaacagg ctgtcccaac gctgaacaat atccagcacg ttccaggtgt cagcgccgta
      181 atgaatactg gctccggcaa taatacatac cccggcgacc gcaaacagaa tataggccac
      241 aactaaaccc agcgtttgcc ccagcgcctg ctcacgaaac gagtgggcgt tttgcgtaaa
      301 gtcggatgcg ctcaccgccg gtgccgccca gaccgcaacc accgcgttta tcaccaccag
      361 aaacaggaag ccactgtttt ctgctttctg aataccgccc ggaatgtagt caaagattgg
      421 accgatcccg accagcgaaa tcgcccaaat cgccataccg ccgaaaacga tatagatgca
      481 cgggttaaga atggcagtga atttatttaa aacttttccg ccgccaaaac caataccaac
      541 gttaaccagc cagaagagta agaaagtaat taatcccggt agagaaaggc ctaacagcgt
      601 gaaatcgcca ccgagagtca aaaatcccgg ccagattttg ccaatcagaa tcaagcaggc
      661 cagtgacccc gcgtaacatt gcaggccaaa ccacataatg gcagcaatac cgcctcttaa
      721 taatccggga aacagtgcac cacgtacgcc gtaagaagca cgcaggatca tggcaaacgg
      781 tacgccgtat ttactgcccg cagcaccgtt taataccatt accgcggcaa tgaaaaaggc
      841 actgaggata attgccagca taatactaaa ggtagacaag ccgagaataa aaaagccgcc
      901 aaccatcaca taattgggaa cgttatgaac cgaacccatc cataaggtaa aatagttaaa
      961 tgttttccag gtccgctgac tttgcgtttt cggcagtaga tcttcgctat agccgcgttg
     1021 ctggaatagt tttctctgat gttccataaa tccctcttaa tttcacgtat cgaataacgt
     1081 tgttttaatc tagctatgag gaacaaataa aataaaaata ttatttttaa tactgaagca
     1141 acatctttgg ctgctttctt tttttaatat tgctggccga ttcattttct gatatcggcc
     1201 atttttattg cgggtatcag gccagtttat ggttagccat taattccagc gcctgcacta
     1261 atgcagagtg atccaactgg ctgccaccgt ttgccgcaca ggtattaaac aattcctggc
     1321 aggtcgcggt gtttggcagg ttcagcgcca gtgctttcgc actttgcagt gccaggttga
     1381 gatctttctg gtgcagcgca attttgaaac ctggattaaa ggtgcgttta atcatgcgct
     1441 caccgtgaac ttccagaata cgtgaggaag caaagccgcc catcagcgcc tggcgcacac
     1501 gtaccgggtc cgcaccggct tttgaagcaa acaacaaggc ttcagaaacc gcttcaatat
     1561 tgagcgccac gataatctga tttgccactt tgcaggtttg accgtcgccg ttaccgccca
     1621 cgagagtgat atttttaccg agcagttcaa acagcggttt tacacgttca aatactgctt
     1681 catcaccgcc aaccataatc gataacgtcc cttcacgcgc gccgatttca ccgccggaga
     1741 ctggcgcatc gagataatcg ccgcccagtt cattcacctg acgagcgaaa cgtttagttt
     1801 caatcgggga aatggagctc atatcaacaa tggttttgcc cttcagcgag gctttggtac
     1861 aaccattttc accaaacaga acgtcttcaa cctgtggcgt atccggcacc ataataaaaa
     1921 tgatgtccga tgcatctgtt acctggcgcg cagtttcaac actaacggcg cccagtgaca
     1981 gtaattcatc agcaaccgga ccaatggttg tgacatgcag ttgatgaccg gcacgcgcca
     2041 gattaatggc catcggtgta cccataatgc ctaagccaat aaatcccagt ttcataatta
     2101 acctctttta aatttcgctt ttcctgaatt cagacaacac gatcccctgc caacttagcg
     2161 gcctaaaaaa gcattgtctg aatagcgtta cgttttaacg gtacgggtcc atccagcgta
     2221 aaccggcttc cgtggtggtt tggggtttat attcacagcc aacccaaccg ttgtagtcag
     2281 aattttcaat taccgtaaag agatattcgt aattaatttc tccggttccc ggttcgccgc
     2341 gatgcggatt atcagcaatt tgcaggtgac caattttatc ggcccactga gtcatggtat
     2401 tggttaattc accttccatc cgctgcatgt gataaatgtc atactgaatt ttcaaattgc
     2461 agcaaccaac atcgtcaatc agtttcagtg cctgccgggt tccggtgaga tgaaaaccag
     2521 gaatatcaaa atggttaata ggttcaatca gtaataaaat atcttctttc atcagcatat
     2581 tcgcagcata acgcaggttt tctacaagcg ttgtgtgaat ctgttcactg ctgaaaccag
     2641 tcggtgtttt accgaccaga cagttaattt ttttattacc cagcgcacga gcataacgaa
     2701 tcgctgctgc tacgccatcc cgaaactctt cttcacggcc aggaatacag gcaatacccc
     2761 gctcgcccgc cgcccagtca cctgccggta aattgtgcag cgtatgttca agtttattac
     2821 tcgccagcac ctgttttaat tcttcaatgt cgtagtcata agggaacata aattcaacgc
     2881 cgcgaaaacc acactgcgca gctttctcaa aacgggcgag aaaatcatat tcaccaaata
     2941 acatcgataa attagcagag aaacgtaaca ttatttatct cccttattca tagtgcatga
     3001 aacaggtttc agtcggtgca tccgctgcgt tatcggcgat atcttcaaat tccatgacgt
     3061 tatccagttc actgcccatc gaaatattag tcacacgctc gagaataact tccacgacta
     3121 ccggtacccg atattgcgcc attaagattt tcgcctgttc aaaggctggt gcaatatctt
     3181 ccggtttgaa aacgcgaatt gctttacaac ctaaaccttc cgctactttt acgtggtcga
     3241 cgccataacc gttcacttcg ctggagttaa tattttcgaa cgcgagctgt acgcagtaat
     3301 ccatatcaaa ggcacgttgc gactggcgaa tcagacccag ataggcgtta ttgaccagta
     3361 catggatgta cggaatgttg aactgtgcgc caacggctaa ttcttcaatc aggaactgga
     3421 agtcgaagtc accggaaatc gccaccacat tgcgctctgg atcagcggca caaaccccca
     3481 gcgccgccgg aatcgtccag cccagcgggc ctgcctgccc acagttgatc cagtggcggt
     3541 ctttaaagac atgcagcatt tgtgccgcag cgatttgtga caggccaatg gtggtgacat
     3601 aacaaacatc gcggccaaag gctttgttca tctcttcata cacgcgctgc ggtttcaccg
     3661 gcacgttgtc gaagtgggtt ttgcgcagca aagtgcgttt gcgctgctgg cagtcggcga
     3721 cccactcttt acgacacggc agacgaccgg ctttttgcat ctcctgcgcc acttcaacca
     3781 gcagcgtcag cgccgcttta gcatcagaga caatgccaag atccggacac agcacgcggc
     3841 caatttgcgt cggctcaata tcgatatgaa cgattttgcg cccttcggtg tatttctcta
     3901 ccgaaccggt atgacggtta gcaaaacggt taccgatacc aaacaccatg tcggacgcca
     3961 gcaacgttgc attaccgtaa cgatgcgcgg tttgcaggcc caccatcccg gccatcagtt
     4021 catgatcgtc cgggatacag ccccagccca tcagcgttgg gatcaccgga atgctggtca
     4081 gttcagcaaa ctgttgtaac agtacagctg cgtcagcatt aattaccccg cctccggcaa
     4141 caatcaccgg acgttcggcc tggattaaca tttctacagc tttttcgatc tgcatacggc
     4201 tggcagcagg tttgtagacc ggcagcggtt cgtacatatc aggatcaaac tcgatttccg
     4261 caacctgtac gtcgaacggt aaatccacca gtaccggacc cggtcgacca gaacgcatca
     4321 ggtgaaacgc ctgttgcagc acacgaggca ccagcgccgc ttcacgaact gtaaccgcca
     4381 ttttgctgac cggtttagca attgcttcaa tatcaacggc ctggaaatct tctttatgca
     4441 gacgggcgcg cggagcctgg ccggtaatac acagaatagg aatggaatca gcagatgcgg
     4501 aatagagcgc ggtgatcatg tccgtgcccg caggaccgga agtccccaga catacgccga
     4561 tattccctgc cgttgcgcgg gtataacctt ccgccatgtg cgaagcacct tccacatgac
     4621 gcgccagaat gtgacgaata ccgccgtgct tacgcatcgc tgagtagaac ggattgattg
     4681 cagctcccgg aacgccgaag gcggtggtga taccttcttt ctccagcaca tacattgccg
     4741 cgtcaacggc tctcattttt gccattttat tcctacctct attaattgga aaaattttcc
     4801 aactttcaaa ttttgtcaaa aaaacccgct ccgcagagcg ggatacgaca gacactatag
     4861 atgtgctttc agtcccaacg ccgtgctgat atcgcgggcg gtgtctctga ccagctcacc
     4921 ctgactgaca aaacgatctt ctgtcagtct tgatgaaggc ccggagatgg agatagcggc
     4981 aacaacacta cctacatcat cgtaaattgc tgaagctatg caattcaggc cgacaacatg
     5041 ctcttcttta tctacggtat agcccagttc acgcgcttgt tccaggtcct tcagcaaggt
     5101 gggcatatcc acaagtgtcg ttggcgtaaa ctgctgcaaa ccggtttgca gaatgatgct
     5161 catcaactct tcttccgcca gcggataaag cagcgccttg cccgctccgg aagcatgcag
     5221 cggcagacga ctgcccagcg gcgcacacat cctgaccatc gatttacact ctaactgacc
     5281 aattaatacc gcttcattgc cgttacggat cgcgacattg accgtttcgc cggaaagtaa
     5341 catcaggcgg cgcataaacg gcccggcgac ggagaggaca tcgcggttat ggatgtacgc
     5401 tgcaccgacg ttaaagacac ctaatcctat atgccaccag cctaactgat tgtcctgata
     5461 gacaaaatcc gctgcctgta aaaccttcag caagcgaaag gtcgtggaga gcggcaaatc
     5521 cagattgaga gagatatcgc taaccgacga acttccccca cttttttcca gatattgcag
     5581 aatcgcaatt ccccgctcta acgcctgtgc gcccttctgt gctacaggct ccgcctgtcc
     5641 tggcctgccg cgccgtctaa cttccgtcat acctacgtta actccgacct acaaatgagc
     5701 ataaacaatg aacaattcgt ttatcttatg caagtcggtt gcaggcgtca cgcaaaacag
     5761 agttcctgtt caggaatact ttcaacatca cagttgtcac tgccgccgcg atcgatggtc
     5821 agaaaatcgg tgacgcgctg ccaggcgaaa agtgggtgat gccagacgtt acgatggtaa
     5881 ttcactccct gttcgccatt ggtaataaac gcccgcaggg ttgacaggtc tggtttgtcg
     5941 tcacctaacg ccaccaccac cacaaacact tcacctttca tcgggataaa cgcctgtgta
     6001 cccagcggat gacgttcgag ttcgtgaatg gtcagcggca gattcgccgg ttgcgcgcgg
     6061 ttaatgctga taagcgtacg gtcttgctca agaatctcaa ccagcgccaa atcgtggtaa
     6121 cgctccacca gtccattgtt aatatggaaa aaatcccgtt tctgcgtttc gattacgtcg
     6181 ccataagcac taaaggcttt ctgacttaac ggtaatacct gaagtttcat ctttttgtcc
     6241 ttgtaacata attccgttca accaccgccg accggtcagc ttggtttcaa taacaggcaa
     6301 tctaaaacct taagagaaca acatcaacac aaaagttgga atatttttcc aaaactagat
     6361 ttagtccaca aattgaacag ggttatcatg taaaaatact gataaatcag aggataagaa
     6421 aatcacgcaa cttgcggatt taaaagggga tacctgaaga tgttcgatcc agaaaccttg
     6481 cggactttca ttgcggttgc tgaaacaggt agtttttcaa aagcggcaga acgattatgt
     6541 aaaaccacgg cgacgatcag ttatcgcatt aaacttctgg aagagaatac cggagtggcg
     6601 ctgtttttcc gcacgactcg cagcgtgacg ttgacggcgg ctggcgagca tctactttgt
     6661 caggccagag actggctgag ctggctggaa agtatgccca gcgagttaca acaggtgaat
     6721 gatggcgtgg aacgccaggt gaatatcgtc atcaacaacc tgctctataa cccccaggcc
     6781 gttgccaggc tgctggcgtg gctaaatgaa cgttacccgt ttacccaatt tcacatctcc
     6841 cgacaaatct atatgggcgt ctgggactcg ctattgtacg aaggtttttc actggctatc
     6901 ggcgtcacgg gaaccgaggc gctggcaaat acctttagtc ttgatccctt aggatcggtg
     6961 caatggcgct ttgtcatggc ggcggatcat ccgctggcga acgttgaaga gccgctaaca
     7021 gaagcacagt tgcggcgctt tccggcggtc aatattgaag acagcgcccg caccttaacc
     7081 aaacgcgtcg cctggcgatt gccggggcaa aaagagatta ttgttcccga tatggaaacg
     7141 aaaatcgccg cccatctggc gggcgttggc attggttttt tgccaaaatc actttgccag
     7201 tcaatgctcg ataatcaaca actggtcagc cgggtaatcc caacgatgcg ccctccttcg
     7261 ccattgagtc tggcatggcg caaatttggc agcggcaaag cggtagaaga tattgtgacc
     7321 ttgtttaccc agcgcaggcc ggaaatcagc ggatttttag aaattttcgg caacccacgc
     7381 agttaaaaat caagtttcct tgcgcgttgg cgcgtaaaat agcgcgcaag ctgatttgag
     7441 gttcactttt tactatgcaa gagagacaca cggaacagga ctatcgtgcc ctgctgattg
     7501 ctgatacgcc cattattgat gttcgcgccc ccatcgagtt tgagcaaggc gcaatgcccg
     7561 ccgctatcaa cctgccgtta atgaataacg atgaacgcgc cgccgttggc atctgctata
     7621 aacagcaagg gtcagacgcg gcgctggcac tggggcataa actggtggcg ggtgaaattc
     7681 gtcagcagcg catggacgcc tggcgggcag cgtgcctgca aaatccgcac ggtattctct
     7741 gctgcgcccg tggcggtcag cgctcacata ttgtgcaaag ctggttgcat gacgcgggga
     7801 ttgattatcc gctggtggaa ggcggttata aggcactgcg ccagaccgcg attcaggcga
     7861 ctattgaact ggcacaaaaa ccgatagtgc tgattggcgg ttgtaccggc agcggtaaaa
     7921 cgctgttagt gcagcaacag ccgaacggtg ttgatctgga agggttggcg cgtcatcgcg
     7981 gttcggcgtt tggtcgcacc ttacaaccac aacttagcca ggcgagtttt gaaaacatgc
     8041 tggctgccga aatgctaaaa accgacgccc atcaggattt gcgcctgtgg gtgctggaag
     8101 atgaaagccg gatgatcggt tcgaatcacc tgccggaatg tctgcgcgaa cgaatgactc
     8161 aggcgacgat tgcggtggta gaagatccgt ttgagatccg tcttgaacgc ctgaacgaag
     8221 aatatttctt gcgtatgcat catgatttta cccacgctta tggcgacgaa cagggctggc
     8281 aggagtattg cgaatacctg catcacgggc tttcggcgat taaacgtcgg ctgggactac
     8341 aacgctataa cgaactggct gcaaggctgg atgcggcgct gacaacgcaa ctcaccaccg
     8401 gcagcaccga cggtcatctg gcctggctgg tgccgttact tgaagaatat tacgacccga
     8461 tgtatcgcta tcagcttgag aaaaaagcgg aaaaagttgt ctttcgcggt gagtgggcgg
     8521 aagtggcgga atgggttaag acttatgcct gtggttatta acccacaaaa atgcttttcc
     8581 gttcctcttt aataaattgt gcaactggtt aactaccagt t
//
LOCUS       DAPOXO010000144         8437 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.144, whole genome shotgun sequence.
ACCESSION   DAPOXO010000144 DAPOXO010000000
VERSION     DAPOXO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8437
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.144"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..341)
                     /locus_tag="ROH59_004706"
     CDS             complement(<1..341)
                     /locus_tag="ROH59_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDX4807097.1"
                     /translation="MLLSIITVAFRNLEGIVKTHASLAHLAQADDISFEWIVVDGGSN
                     DGTREYLENLNGIYNLHFVSEPDNGIYDAMNKGIEMAQGKFALFLNSGDIFHQDAAYF
                     VRKLKVQKDNV"
     gene            complement(422..1642)
                     /gene="wcaD"
                     /locus_tag="ROH59_004707"
     CDS             complement(422..1642)
                     /gene="wcaD"
                     /locus_tag="ROH59_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative colanic acid polymerase WcaD"
                     /protein_id="HDX4807098.1"
                     /translation="MSTSIRICSYLLLPLIYLLVNVKIAQLGESFPITIVTFLPVLLL
                     LFLERISVKKLMIALGIGAGLTAFNYLFGQSLDASKYVTSTMLFVYIVIIIGMVWSIR
                     FKTISPHNYRKILRFFYLVVGLVVVLAAVEMAQIILTGGSSIMESISKYLIYSNSYVL
                     NFIKFGGKRTTALYFEPAFFALALISIWLSIKQFGIKTPKTDAMILAGIILSGSFSGV
                     MTFILFYLLEWAFQYLNKEAIKKKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGS
                     SSYYRIVGPLVMVGYSLTHIDGVVRFGSLYEYVASFGIFNGADVGKTIDNGLYLLIIY
                     FSWFAVFLSLWYMGKVIKMMINAFGDNRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIV
                     CPFILRKALNIHPK"
     gene            complement(1617..2834)
                     /gene="wcaC"
                     /locus_tag="ROH59_004708"
     CDS             complement(1617..2834)
                     /gene="wcaC"
                     /locus_tag="ROH59_004708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaC"
                     /protein_id="HDX4807099.1"
                     /translation="MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGK
                     ESVSHQNYPQVIKHTPRMTAMANIALFRLLNRDLFGNFNELYRTITRTPGPVVLHFHV
                     LHSYWLNLKSVVRFCEKVKNHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP
                     TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIIN
                     NGIDMATEAILADLPPVRETQGKPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHT
                     FGKFSPFTAGNVVNHGFETDKRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVI
                     ATHSDAAREVLQKSGGKTVSEEDVLQLVQLSKPEIAQAIFGTTLAEFSQRSRAAYSGQ
                     QMLEEYVNFYQNL"
     gene            complement(2831..3319)
                     /gene="wcaB"
                     /locus_tag="ROH59_004709"
     CDS             complement(2831..3319)
                     /gene="wcaB"
                     /locus_tag="ROH59_004709"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaB"
                     /protein_id="HDX4807100.1"
                     /translation="MLEDLRANSWSLRPCCMVLAYRAAHFCSVWRKKNVLNNLWAAPL
                     LVLYRIITECFFGYEIQAAATIGRRFTIHHGYAVVINKNVVAGDDFTIRHGVTIGNRG
                     ADNMACPHIGNGVELGANVIILGDITIGNNVTVGAGSVVLDSVPDNALVVGEKARVKV
                     IK"
     gene            complement(3322..4161)
                     /gene="wcaA"
                     /locus_tag="ROH59_004710"
     CDS             complement(3322..4161)
                     /gene="wcaA"
                     /locus_tag="ROH59_004710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaA"
                     /protein_id="HDX4807101.1"
                     /translation="MKDNPLISIYMPTWNRQQLAIRAIKSVLRQDYNNWEMIIVDDCS
                     TSWEQLQQYVTALNDPRITYIHNDINSGACAVRNQAIMLAQGEYITGIDDDDEWTPNR
                     LSVFLAHKQQLVTHAFLYANDYVCQGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQV
                     FTWAWRFKECLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSSP
                     KKFSGYFHFYRKHKDKFDRASKKYQLFTLYQIRNKRMTWRTLLTLLSVRNGKRLADGI
                     RGR"
     gene            complement(4290..6452)
                     /gene="wzc"
                     /locus_tag="ROH59_004711"
     CDS             complement(4290..6452)
                     /gene="wzc"
                     /locus_tag="ROH59_004711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416564.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="HDX4807102.1"
                     /translation="MTEKVKQHAAPVTGSDEIDIGRLVGTIIEARWWVIGITAVFALC
                     AVVYTFFATPIYSADALVQIEQSSGNSLVQDIGSALANKPPASDAEIQLIRSRLVLGK
                     TVDDLDLDIAVSKNTFPIFGAGWERLTGRQNETVKVTTFNRPKEMADQVFTLNVLDNK
                     NYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHASPGSEFTVTKYSTLGMINQLQNSL
                     TVTENGKDAGVLSLTYTGEDREQIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQL
                     PEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLY
                     TKVHPAYRTLLEKRQALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNK
                     EQELKITEASTVGDVRIVDPAITQPGVLKPKKVLIILGAIILGLMLSIVGVLLRSLFN
                     RGIESPQVLEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIE
                     AIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLIDCDMR
                     KGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSER
                     FAELVKWASKNYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSR
                     FEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK"
     gene            complement(6455..6898)
                     /gene="wzb"
                     /locus_tag="ROH59_004712"
     CDS             complement(6455..6898)
                     /gene="wzb"
                     /locus_tag="ROH59_004712"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase Wzb"
                     /protein_id="HDX4807103.1"
                     /translation="MFNNILVVCVGNICRSPTAERLLQRYHPELKVESAGLGALVGKG
                     ADPTAISVAAEHQLSLEGHCARQISRRLCRNYDLILTMEKRHIERLCEMAPEMRGKVM
                     LFGHWDNECEIPDPYRKSRETFAAVYALLERSAHQWAQALNAEQV"
     gene            complement(6904..8043)
                     /gene="wza"
                     /locus_tag="ROH59_004713"
     CDS             complement(6904..8043)
                     /gene="wza"
                     /locus_tag="ROH59_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein Wza"
                     /protein_id="HDX4807104.1"
                     /translation="MMKSKMKLMPLLVSVTLISGCTVLPGSNMSTLGKDVIKQQDADF
                     DLDKMVNVYPLTPRLIDQLRPRPNVARPNMTLESEIANYQYRVGPGDVLNVTVWDHPE
                     LTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKVHVVGKTLAEIRSDITGRLATYIADPQ
                     VDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTILDAINAAGGLTDTADWRNVVLTHN
                     GREERISLQALMQNGDLNQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSGM
                     TLTEALGNAEGIDMTTSNASGIFVIRPLKGESGRNGKIANIYQLDMSDATSLVMATEF
                     RLQPYDVVYVTTAPVSRWNRLINQLLPTISGVRYMTDTASDIHNW"
BASE COUNT         2014 a         2194 c         2087 g         2142 t
ORIGIN      
        1 atcacgttat ctttttgcac ttttaactta cggacaaaat atgcggcatc ctgatgaaaa
       61 atatcgcccg agttgagaaa caacgcgaac ttgccttgcg ccatttcaat acctttgttc
      121 atggcgtcgt agataccgtt atctggttcg ctgacaaagt gtaagttata gataccattg
      181 agattttcca gatactcacg ggtgccgtcg ttggaaccgc catcaacaac aatccattcg
      241 aagctgatat cgtccgcctg cgccagatgc gccagcgagg cgtgtgtttt gactattcct
      301 tcgaggttac gaaacgcgac agtgattatg ctaagcaaca tgttttacct cgtaataccc
      361 gtcatacttc aagctgcatg tgcgttggtt ttcctcgctc acccacttcc tgcaactcga
      421 attatttagg gtgtatattt aacgcttttc gcaaaataaa cgggcagacg attaaaaacg
      481 catattctgg gctaaatatc gaaccggtaa aaaacagcga taccggagta aaaagatata
      541 attgcacgcg aaaattgcgg ttatcaccaa aagcgttgat catcattttt atcacttttc
      601 ccatgtacca cagcgataaa aacactgcga accaggaaaa ataaataatc agcagataca
      661 aaccattgtc tatggttttt ccgacatccg caccgttaaa tattccgaat gatgcgacat
      721 attcataaag tgagccaaat ctgactacac cgtcaatatg ggttaaagaa taaccgacca
      781 tcaccagcgg accgacaata cgataatacg atgacgatcc ttctgtacct aaatcgccca
      841 gacgggtgga aatataaggg aacgcgatta ccacaccaac caggaataca gccagagaaa
      901 tcaatgctaa cggtaacttt ttcttaatcg cctctttatt cagatattga aatgcccact
      961 ccagcaaata aaaaaggata aaggtcataa cccctgaaaa tgaaccggat aatattatcc
     1021 ctgcgagaat catagcatct gttttaggcg ttttgatacc aaactgtttg atgctgagcc
     1081 aaattgagat taatgccaga gcgaaaaatg ccggttcgaa ataaagtgct gtcgtgcgct
     1141 tgccgccgaa tttaatgaaa ttcagcacat agctgttgct gtaaatcaga tatttcgaaa
     1201 tcgactccat aatactgcta ccgccggtga ggataatttg cgccatctcc accgccgcca
     1261 gcaccaccac cagcccgacc accagataaa agaaacgtaa tatcttgcga tagttgtgtg
     1321 gcgaaatcgt tttaaagcga atactccaca ccatgccaat aatgatcaca atatagacaa
     1381 acagcatggt tgaagtgacg tatttactgg catccagcga ctgaccaaac aggtagttaa
     1441 acgccgtaag tcccgcgcca atccccaagg caatcatcaa ttttttaacg ctgatgcgct
     1501 ctaaaaacag cagtaacagg acaggtaaaa aagtgacgat ggtgatgggg aaactttcgc
     1561 caagctgggc gattttgacg ttaaccagca ggtagatcag cggcagcagc aggtagctac
     1621 agattctgat agaagttgac atactcctcc agcatctgtt gtccactgta ggcggcgcgg
     1681 ctgcgctggc tgaattcagc cagcgtggta ccaaatatcg cctgtgcgat ttccggtttg
     1741 cttaactgca ccagttgcag cacatcttct tcgctgacgg ttttaccacc ggatttttgc
     1801 agcacttccc gcgccgcatc gctatgggtg gcgatcaccg gcacgccaat cgataacgcc
     1861 tcacacaaaa tcagcgggta gttatcgacg cgagaactga acaccagcgc atccatctga
     1921 ttgagcacgc tcattaactt gcgcttgtca gtttcaaagc cgtgattgac aacgttacca
     1981 gcggtgaacg gcgagaactt accaaaggta tgcagttcga ttttgtcacc cagcgccatc
     2041 atctcgcgta ccagttgctg gttagttttg ccgtcgtaac gcaggtcatg cgccaccacc
     2101 gcgattttcg gcttgccctg ggtttcgcgt accggaggca agtccgccag aatcgcttcg
     2161 gttgccatat caatgccatt attgataatc cggcaacgcc ctggaccgta cagactattg
     2221 aaagcatcag ccacatgctg gctgggggaa ataaactgac agcccagtgc cagcatctcg
     2281 cggaataact ggcgtttacc cgccaccagc tggtgcgcgc gatcaatctt caccggtgga
     2341 tagttattta aggtcgggca tttctggcag cccgttttcc agccttcgca accgtcggta
     2401 aaggcgcagc gtccggtaac gctccagtgg tcgtgtagcg tccagaccag agtgacatcc
     2461 ggtttatggt ttttcacttt ttcgcaaaag cgcaccacgc tcttaagatt caaccagtag
     2521 ctgtgcagca catgaaaatg cagaaccacc gggcccggtg tgcgagtaat ggtgcgatat
     2581 aactcattga aattgccgaa cagatcgcga ttaagcagac gaaacaacgc aatgttcgcc
     2641 atcgcggtca tccgtggcgt atgtttgatg acctgcggat agttctgatg gctgacgctc
     2701 tctttgccgc ctttgccgta gccgtagaca aaatgtgacg ccagcccctg ttgcagcgcg
     2761 cgctggtgga gatctaatgc cacacctgct gccccgcctt ccgccagtcg cacattaaat
     2821 tgcagaatat tcatttaatt accttcactc gcgctttttc tcccaccacc agcgcgttgt
     2881 ccgggacaga gtcgagcacc acgctgcccg cgcccacggt gacgttgtta ccaatcgtga
     2941 tatcaccaag aataatgacg ttggcaccga gttcgacgcc gttgccaatg tgtggacatg
     3001 ccatgttatc ggcgccacga ttgccgatag tgacgccgtg acgaatggtg aaatcatccc
     3061 ccgcgaccac gtttttattg atcactacgg cgtaaccgtg atggatagta aagcgtcggc
     3121 ctatggtcgc ggcggcctgg atttcataac cgaaaaagca ttcggtgata atgcgataca
     3181 gcaccagcag cggggccgcc caaagattgt tgaggacgtt ctttttgcgc cacaccgaac
     3241 aaaaatgagc ggcacgatag gcaagaacca tgcagcacgg gcgtaaactc cagctgttgg
     3301 cgcgcagatc ttccagcatc tttagcgccc ccgaatacca tcagccagac gtttgccgtt
     3361 acgcaccgac agcagcgtca gcaaagtgcg ccaggtcatg cgtttattgc ggatctggta
     3421 gagggtaaac agctgatatt ttttgctggc gcggtcgaat ttgtctttgt gcttgcggta
     3481 aaagtggaag tatccggaga attttttcgg tgacgaggtg atctgcattt cgccgtgatt
     3541 gatatgcagg atctgcgtcg cctcttccac tttccacggt tcgccgtact ccaccaccat
     3601 ccgcaggaag atgtcgtaat cctgtgccgc tttcagttcg gtatcgaaca agcactcttt
     3661 gaaacgccac gcccaggtaa agacctgatt gccaatgata ttgcgtttgt aaaacaggcg
     3721 gcgtgaatac ggcgatttgg gatacagcgg caagcttgcc ggttgggaat aaacttcgcc
     3781 ctggcaaacg tagtcgttag cgtacaaaaa ggcgtgtgtg accagttgct gtttatgggc
     3841 gaggaagacg ctcaggcggt tgggtgtcca ttcatcatcg tcatcgatcc cggtgatgta
     3901 ttccccttgc gccagcataa tcgcctggtt acgtaccgcg cacgccccgc tgttaatgtc
     3961 gttgtgaatg taagtgatac gcggatcgtt gagggcggtg acgtactgtt gtagttgttc
     4021 ccaggaggtg gagcaatcat ccacgatgat catctcccag ttgttgtagt cctggcgcag
     4081 gaccgatttt atcgcccgaa tcgccagttg ttggcggttc caggtcggca tatagattga
     4141 aatcagcgga ttgtctttca taggttgttc tcccggagta tcgagatgtt ctgccggttt
     4201 ataagctggt ttacaggttc tgttgccgga tgcggcgtga acgtaggtcg gataagatgc
     4261 gtcagcatcg catccgacag cggatctcgt tatttcgcat ccgacttata ttcgtattcg
     4321 taatagccat aatcctgata cgcgctggcg cggcggaaga tggagttcag aatcacccct
     4381 ttcaccggaa taccgttttg ctcaaagcgg ctcagactgg tttccacttc tttcaatgtg
     4441 ttgaccgcat aacgcgccac catcaacgtg gttccgacat gacgaccaac aattgccgca
     4501 tcggtcactg ccagaatcgg cggcgtatca atcaacacca ggtcgtagtt tttactcgcc
     4561 cacttcacca gttcggcaaa gcgttcgctc attaacagtt cagaaggatt tggcggtacc
     4621 tgaccgcgcg ggatcaggtc aaatttggca atagaggtcg gtttagcagc ggtagtaata
     4681 tcgccctgtc caatcagaat ttccgacagg ccattaacgt tattagtgcc caacagctcg
     4741 tgggtgtagc ctttgcgcat atcgcagtcg atcaacaaca cccgtttatt ggtctggcta
     4801 atcaccgccg ccaggttggc gcagacaaag gttttaccga ttgacgggct aaccccggtc
     4861 atcatcaaca cattgttctg tgcctgcatc atcgcgaagt gcagactggt acgcagacta
     4921 cggatggctt caatcgccag atcggttgga ttccccaccg ccagtagctg gctctgttta
     4981 tagcgtttaa tccctttgat ggttttgacg ctatcgcgcg ctttctgcca ctccgacagc
     5041 gggatgctgg cataaacgct gataccgtgt tcttccagca cctgcgggct ttcgataccg
     5101 cgattaaaca acgagcgcag cagcacaccc acgatagaga gcatcaggcc aaggataatc
     5161 gccccaagga taatcagcac tttcttcggt ttcagtacac ctggctgggt gattgccggg
     5221 tcgacaatgc gcacatcgcc gacggtgctg gcttcggtga ttttcagctc ctgctcttta
     5281 ttcagcagtt gcatatagac ctgctgacca gactcgacat cgcgggtcag acgcacaatt
     5341 tcctgctggg ttttcggcat cgccgttacg cgaccattaa gtttggcttt ttcgtcttcc
     5401 agcgcctgcc gtttctccag cagcgtgcgg tacgccgggt gaactttggt gtacagcttg
     5461 gagatttccg cctctttaaa ggtcagttcg ttcaactgcg cgtcgatgtt caccatcgaa
     5521 tcgagcaccg ctttcgcttc cagcggcaga tcaactgaat ctttatcctg acggaaggca
     5581 ttcagtttgt tttcggcaac atcaaggcgg ctacgtactt ccggtaactg ttgcgcgagg
     5641 aaagcgaggc ttttcgacgc ttccgccgat ttgcgctcaa tattttgttc ctgatagtta
     5701 cgggcgatgc tgttaagaat gtcgcggatc tgttcgcgat cttcaccggt gtaagtcagg
     5761 ctcagaacac ctgcgtcttt gccgttctcc gttaccgtca ggctgttttg cagttggttg
     5821 atcatcccca gcgtggagta tttggtgacg gtaaactcac tgcccgggct ggcgtgaatg
     5881 gcttcaacca tcagcgtgac gccttctttt ttcagcatct ggcccgcttg cccacgggcg
     5941 ctaaagccgc catcgctgct cagggtgtag tttttgttgt ccagcacatt aagcgtaaac
     6001 acctgatccg ccatctcctt cggtcggtta aaggtggtca ctttcaccgt ctcgttctgg
     6061 cgtcccgtca ggcgctccca gcccgcaccg aaaatcggga acgtgttttt gctcaccgca
     6121 atatcaaggt cgagatcgtc caccgtttta ccaagcacca gacgcgaacg aatcaactgg
     6181 atctcggcgt ccgatgcagg cggtttgttg gctaatgccg atccgatatc ctgcactaac
     6241 gaattgccgc tgctttgttc gatttgtacc agtgcgtcgg cgctgtatat cggcgtagcg
     6301 aagaaggtgt aaaccacggc acagagggcg aatacggcgg taatgccaat cacccaccag
     6361 cgtgcttcaa tgatggtgcc aaccaggcga ccaatatcga tttcatcact gcccgttacc
     6421 ggagcggcat gttgttttac tttttctgtc attcttatac ctgctctgcg ttcaatgcct
     6481 gcgcccactg gtgggcagac cgttcaagta atgcgtacac cgctgcaaac gtttcccggc
     6541 ttttgcgata tggatcgggg atttcacatt cgttatccca gtgaccaaac agcatcactt
     6601 tgccgcgcat ctcgggtgcc atctcgcata agcgttcgat atggcgcttt tccatggtca
     6661 gaatcaggtc gtagttgcga cacaggcggc ggctgatttg ccgtgcacag tgaccttcca
     6721 gggacagttg atgttctgcg gcgacgctga tagcggtagg atcagcgccc ttaccgacca
     6781 acgcgccgag tccagcggac tccactttta gctccgggtg ataacgttgc agtaagcgtt
     6841 ccgccgtcgg ggaacggcaa atattgccga cacagacaac taagatgttg ttaaacatga
     6901 cgattaccag ttatgaatgt cgctggctgt atccgtcatg taacggacac cgctaatagt
     6961 tggcagcaac tgattgatca gacggttcca gcgggatacc ggggcggtgg tgacatacac
     7021 cacgtcataa ggttgcaggc ggaattctgt cgccattacc agcgacgtcg catcggacat
     7081 atccagctgg tagatattgg caatcttgcc gttacgcccg ctctcgcctt tcagcggacg
     7141 aatgacaaag atgccgctgg cgttggaggt ggtcatgtcg atgccttcag cattgcccag
     7201 ggcttcagtc agggtcatgc cgctaaagtc cattttcagg gtgctctgtt tcttcacttc
     7261 acccatcaca aacactttca gatcatcatt acgtggcacg taaagaatat cgccggggta
     7321 aagcagtcgg ttctgattga ggtcgccgtt ttgcatcagc gcctgcaaag aaatgcgctc
     7381 ttcacgacca ttgtgtgtta gcaccacgtt gcgccagtca gcggtgtcgg tcaggccacc
     7441 tgcggcgttg atggcgtcga gaatggtcag tggcacgttg gtaatggcct gttgaccgga
     7501 tttattcacc tgaccggaga tataggcttt ttgcgagcgg aaggcggcga tattaacgtc
     7561 cacctgcggg tcagcgatgt acgtcgctaa gcgcccggta atatcactgc ggatttcagc
     7621 gagcgttttc cccaccacgt gaactttgcc gatatacggg tagaacatgg tgccgtcagg
     7681 ctgtacccag ttgccggtgt cgctggagct gcggtactga ccggctggcg tggtgagttc
     7741 cgggtgatcc cagacggtga cattaagaac gtcccccggc ccgacgcgat actggtaatt
     7801 cgcgatctcg ctttccagcg tcatattggg gcgcgctaca ttcgggcgtg ggcgtaattg
     7861 atcaatcagg cgcggggtca gcggataaac attcaccatt ttgtcgagat cgaaatcagc
     7921 gtcctgctgt ttgatgacgt ctttccccag cgtcgacata ttgctgcccg gaagtactgt
     7981 gcaaccgctt atcaaggtta ctgacaccaa taatggcatc aatttcattt tggatttcat
     8041 cattgtttat ttatcacttt ggcagagtaa ttatcctgtg cactattaat agcaatgtcg
     8101 ccatgcacat ttaccttgca gttaattgaa taaaaattta actggcatca gtcctaaaaa
     8161 aaattgattt catccgcagg ctattgacag aataattcag actggtcttt caggcatcca
     8221 gacacgctac cgcccctggc tttttagcta ccaacacact gatttagctt aatttttcac
     8281 accctctctg catacagtcg ttgatgagaa agggttattg cggaaattaa cttccgaata
     8341 taaggtgaca ttatggtaat tgaatattgg ctctccaata atgcaggagg aagtgttaca
     8401 gctaacggaa tagcaggcaa ggtaacaatt cggcaat
//
LOCUS       DAPOXO010000145         8386 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPOXO010000145 DAPOXO010000000
VERSION     DAPOXO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8386
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.145"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            183..1364
                     /gene="setB"
                     /locus_tag="ROH59_004714"
     CDS             183..1364
                     /gene="setB"
                     /locus_tag="ROH59_004714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HDX4807105.1"
                     /translation="MHNSPTVTSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTVEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKD
                     V"
     gene            complement(1361..1615)
                     /locus_tag="ROH59_004715"
     CDS             complement(1361..1615)
                     /locus_tag="ROH59_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDX4807106.1"
                     /translation="MECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMIWLIDLEMLTAP"
     gene            1770..2342
                     /gene="yeiP"
                     /locus_tag="ROH59_004716"
     CDS             1770..2342
                     /gene="yeiP"
                     /locus_tag="ROH59_004716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HDX4807107.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            2565..4031
                     /locus_tag="ROH59_004717"
     CDS             2565..4031
                     /locus_tag="ROH59_004717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDX4807108.1"
                     /translation="MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLT
                     DRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHECLN
                     AKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHS
                     APGILVEALKRRRERGHTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHV
                     SFPGTMVDRIVPAATNESLAEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVA
                     GVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDE
                     QAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRE
                     TDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLRE
                     IFGDDLPDNPHFVQVIEQAWQQIAQFGAHQALLNTLKI"
     gene            4149..5135
                     /gene="yeiR"
                     /locus_tag="ROH59_004718"
     CDS             4149..5135
                     /gene="yeiR"
                     /locus_tag="ROH59_004718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding GTPase YeiR"
                     /protein_id="HDX4807109.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRATPE
                     SEQALERWWQQNGGDRQLIHSEHGKIDGHLLDLPRRNLAELPASAAHSHQHSVKKGLA
                     ALSLPEHQRWRRSLNSGQGHQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            5174..5887
                     /gene="lpxT"
                     /locus_tag="ROH59_004719"
     CDS             5174..5887
                     /gene="lpxT"
                     /locus_tag="ROH59_004719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HDX4807110.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPINHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIIGLVMLLTA
                     VVLNQLGQALIPVKRASPTLTFTNINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            6299..6865
                     /gene="mepS"
                     /locus_tag="ROH59_004720"
     CDS             6299..6865
                     /gene="mepS"
                     /locus_tag="ROH59_004720"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HDX4807111.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            7046..>8386
                     /locus_tag="ROH59_004721"
     CDS             7046..>8386
                     /locus_tag="ROH59_004721"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDX4807112.1"
                     /translation="MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGLALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVVYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAEAQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPAHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEREATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIG"
BASE COUNT         2008 a         2045 c         2071 g         2262 t
ORIGIN      
        1 atttttccta attgctgatg ggaaaatccg ttatcagcaa tttcatttca gcagtgtcag
       61 cagccaatca gcaacagtga aatggcattt tgattattcg tggcgctttt gatttcgctg
      121 tctgtttatt ttctgacaag cagcgtaaac tccgcgtctt cctcttccag tgatcgacca
      181 gcatgcataa ctcccccaca gtcaccagcg cgaaatcgtt tgacctgacc tcgacggcgt
      241 ttttaatcgt tgcctttctc accggtattg cgggcgctct gcaaaccccg acactcagta
      301 tttttcttac tgatgaagta catgcccgtc cggcgatggt gggattcttc tttaccggca
      361 gcgctgtcat tgggattctg gtgagtcagt ttctcgccgg gcgctctgat aagcgcggcg
      421 atcgcaaatc gctgattgtc ttttgctgcc tgttaggcgt gctggcctgc accctttttg
      481 cctggaatcg caactacttt gttttgctat tcgttggcgt ctttcttagc agctttggct
      541 cgaccgctaa cccgcaaatg tttgcccttg cccgtgaaca tgctgacaaa accggacgtg
      601 aggcggtgat gttcagctct tttttacgcg ctcaggtttc actggcatgg gtcattggcc
      661 caccgctggc ttatgcctta gcgatgggtt tcagctttac ggtaatgtat ctgagcgcag
      721 cggtagcgtt tattgtttgc ggcgtgatgg tgtggctgtt tttgccgtcg atgcaaaaag
      781 agcttccgct ggcgaccggc acggttgaag cgccgcgccg taaccgtcgc gatacgttgc
      841 tgctgtttgt catttgtaca ttgatgtggg gctcgaacag cctgtacatc atcaacatgc
      901 cgctatttat tatcaacgaa ctgcatcttc ccgagaaact ggccggtgtg atgatgggga
      961 ccgccgccgg gctggaaatc ccgaccatgt tgatcgccgg atattttgcc aaacgtctgg
     1021 gtaagcgctt cttaatgcgc gttgctgccg tgggtggcgt ctgtttttac gcaggaatgc
     1081 tgatggcgca ttcacctgtc attctgttgg gcttgcagct gctaaatgct atttttattg
     1141 gcattcttgg cggcatcggg atgctctatt ttcaggattt gatgcccggt caggcaggtt
     1201 cagccaccac gctctatacc aacacttcgc gcgtgggctg gatcatcgca ggatcagtgg
     1261 cgggcatcgt cgccgagatc tggaattatc acgctgtgtt ctggtttgcg atggtgatga
     1321 ttatcgccac tctgttttgc ttactgcgaa ttaaagatgt ttaaggcgcg gtcaacattt
     1381 ccagatcgat aagccagatc atggcctgct gacgcgagtt accgcacatt tcagcgctgg
     1441 cttgtaagcc tgcacagact ttcggtcgca gtggcgaggt gaaaatttta cagcgttgct
     1501 gttcatcaag ctgaatgcag ggagtattgg cgggcttgcc atctggcata ccgggaatag
     1561 ggctggaaat tgaaggggca gtgcaacacg ccccgcaacc cggacggcat tccatacgtt
     1621 gttctcttaa ggttaaccac cggattgatg agcgcgcaca gtaccacctt ttttgcacca
     1681 gcaaaagtgc gaataccact tgcccgaaag gcccgtcgcg agtactttgt cgcgatattt
     1741 ttgacatttt tgactacagg aatttttcga tgccaagagc gaacgaaatt aaaaaaggta
     1801 tggtactgaa ttacaacggc aaactgctgc tggttaagga cattgatatt cagtcgccca
     1861 ctgcccgcgg tgccgctacg ctgtacaaaa tgcgtttttc tgatgtccgt accgggctga
     1921 aagtagaaga gcgtttcaaa ggtgatgata tcgttgacac cgtgacgctg acccgccgtt
     1981 acgttgactt ctcctatgtc gatggcaacg aatatgtctt tatggataaa gaagactata
     2041 ccccgtatac cttcaccaaa gatcagattg aagaagagtt gctgtttatg cctgagggcg
     2101 gcatgccgga catgcaggtg ctgacctggg acggtcagtt gctggcgctt gagctgccgc
     2161 agaccgttga tctggaaatc gttgaaactg caccaggtat caaaggggca tctgccagcg
     2221 cccgtaacaa accggcgaca ttgagcactg gtctggtgat tcaggtacca gaatacttaa
     2281 gcccgggcga aaaaattcgt atccatatcg aagaacgccg ttatatgggt cgtgctgact
     2341 aacttcagcc gcatgcagaa aagggatagc tcaggctgtc ccttttttaa tttattatac
     2401 caatcttcta ttttgcgctt cctgaacacc ttacgcccgc aattttcact cgttgattga
     2461 tcgccctcac acttcatcgc attaacaatc cagaccaatt tcaattgctg tcatataact
     2521 ttacactgtc attgttaatt aatcgttact aagacgtgac tcctatgaat acaatcgcct
     2581 ccgttacgct cccgcatcat gtacacgctc cacgctacga tcgacagcag ttgcaatcac
     2641 gtatcgttca ttttggcttt ggagcctttc accgcgcaca tcaggcatta ctgaccgatc
     2701 gtgtgctgaa tgcccagggc ggcgactggg ggatctgtga aatcagcttg ttcagcggcg
     2761 atcaactgat gagccagctc cgcgcacaga accatttata taccgtgctg gagaaaggtg
     2821 cggacggcaa tcaggcgata attgtcggtg ccgttcacga atgtctgaat gcaaaactgg
     2881 attccttagc ggcaattatt gagaaatttt gcgagccaca ggtggcaatt gtttccctga
     2941 caattaccga aaaaggctat tgtattgacc cggccaccgg tgcactcgac accagcaatc
     3001 cgcgtattat tcacgatcta caaaaccctg aagaacctca ctccgcgcca ggtattctcg
     3061 tcgaagcact gaaacgccgc cgtgagcgcg gccatacacc gtttaccgtg ctctcctgcg
     3121 acaatattcc cgacaatggc catgtggtga aaaacgcggt gctgggaatg gcagaaaaac
     3181 gttcgccaga actcgccggg tggataaaag aacacgtcag ttttccggga accatggtcg
     3241 accgcattgt tccggctgca acaaacgaat cactggcgga aataagccag catctggggg
     3301 tgaatgatcc ctgcgcgatt agctgcgaac cgtttatcca gtgggtggtt gaagataact
     3361 tcgtcgctgg gcgtcctgcc tgggaagtcg caggtgtaca aatggtgaat gatgtcctgc
     3421 catgggaaga gatgaaactg cggatgctta atggcagcca ctcttttctc gcttatctgg
     3481 gttacctctc aggattcgcc catatcagtg attgcatgca ggatcgcgca tttcgccatg
     3541 ccgccagaac attaatgctg gatgagcaag cgccgacact gcggattaaa gatgtcgatt
     3601 taacacaata tgcggataag ttaattgcac gttttgctaa tccggcactg aaacataaga
     3661 cctggcaaat cgcgatggat ggcagccaga aattaccgca acgcatgttg gcaggtattc
     3721 gcatacatct ggggcgcgaa acggactggt cgttgctggc attaggcgtt gcaggctgga
     3781 tgcgttacgt cagcggcgtt gatgatgccg gaaatgccat tgatgttcgc gatccgctta
     3841 gcgataaaat tcgtgaactt gttgcaggca gcagcagtga acaacgcgta accgccctgc
     3901 tttccctgcg tgaaattttc ggtgatgatc tgccagataa cccgcatttt gtgcaggtca
     3961 tcgaacaagc ctggcaacaa atcgcacaat tcggcgcgca tcaggcgcta ttaaacaccc
     4021 tcaaaattta acgatttctg cggttaaagc ggatgaagct cgccttcgtc cgctctcccc
     4081 ttctcttttc tgcctttttt agccaggatt aacgctcagt taacttacca gagtattgcg
     4141 gagccgttgt gaccagaacc aacctcatca ccggttttct cggcagcggg aaaactacgt
     4201 cgattcttca tctgttagcc cataaagatc ccaacgaaaa atgggcggta ctggttaatg
     4261 aatttgggga agtcggaatt gatggtgctt tgctcgccga tagcggcgca ctgctgaaag
     4321 agatccccgg cggttgcatg tgctgcgtta atggtttacc catgcaggta gggttgaata
     4381 ccttactgcg tcagggaaaa ccagaccgct tgttgataga gccgaccggg ctgggccatc
     4441 cgaaacagat cctcgatctc ttaaccgcgc cagtctatga accgtggata gatctgcgcg
     4501 ccacgttgtg cattctcgat ccacgcctgc tgctggacga aaaaagcgcc agcaatgaaa
     4561 acttccgtga ccagctggct gccgcagaca ttattgtcgc caataaatcc gaccgtgcga
     4621 cgcccgaaag tgagcaagcg ctagagcgct ggtggcagca aaatggtggc gatcggcaat
     4681 taattcacag cgagcatgga aaaattgacg gtcatcttct ggatttgccg cgtcgcaatt
     4741 tagccgagtt gcccgccagc gccgcgcatt ctcatcagca tagcgtgaaa aaagggttag
     4801 cagcgttaag cctgccagag catcaacgct ggcgtcgcag tctgaacagc ggacaagggc
     4861 atcaggcctg tggctggata ttcgacgctg atacggtatt cgacaccatt ggtattctgg
     4921 aatgggcgcg acttgcaccg gtggaacgcg tcaaaggcgt gctgcgtatt cccgaagggc
     4981 tggtgcgaat caaccgtcag ggcgatgacc tgcacattga aacgcaaaac gttgcgccac
     5041 cggacagtcg tattgagctg atttccagca gcgaagctga ctggaatgcc ttgcagagcg
     5101 cgctgttgaa gcttcgttta gcgactaccg cgtaaggttg cctgcgtttt tcagtaagat
     5161 aattagagaa aatatgatta aaaatttgcc gcaaatagtg ttgttgaata ttgtcggcct
     5221 cgcgctgttt ctttcctggt atattcccat taatcatgga ttctggttgc cgattgatgc
     5281 ggatattttt tatttcttta atcagaaact ggtcgaaagt aaggcctttt tgtggctggt
     5341 tgcattgacc aacaatcgcg ctttcgacgg ttgttcactg ctggcgatgg gaatgttgat
     5401 gctgagtttc tggctgaaag aaaacgcccc aggcagacga cgtatcgtga ttattggtct
     5461 ggtcatgcta ttaactgcag tggtattaaa ccagctgggt caggcattaa ttcctgtaaa
     5521 acgggccagt ccaacgttga cttttaccaa tattaaccgc gtcagcgaac tgctctctgt
     5581 tcccacgaaa gatgcctcac gagatagctt tcccggcgat cacggtatga tgctgcttat
     5641 tttttcggca ttcatgtggc gttatttcgg caaagttgct ggccttatcg cccttattat
     5701 ttttgtggtt tttgcgtttc ccagagtaat gattggcgca cactggttta ctgacatcat
     5761 cgtcggttcc atgaccgtga tattgatcgg tttgccctgg gtgttgctga cgccattaag
     5821 tgatcgatta atcacctttt ttgacaaatc actacctgga aaaaacaaac atttccaaaa
     5881 caaataactc acagtaatta acatcatcag gtttattttt atagtgagga taatcctgat
     5941 gatgcgcctc ctgctttcat ccatcgagcg caaaaatcat tctctaagta aatgaatgga
     6001 ttgcatgcgt ttcactcaat cgtactttaa ttgaccaatc ccgctgatta actttctgta
     6061 tcactttttc ttataaaaaa tcatgtaaaa ccgctcgcca agaccgcacc aatcgggtaa
     6121 tctcgaactc gttttgcctc ggcggtagat tatcctcaca gcatataatt ttgtgcgtta
     6181 gtccacagat ttggccttaa ggaattgttt caacatgccc aggtaattag tctcgtgtcg
     6241 cttggcattt ttttataacg atatttgtcg ttaaggactt caagggaaaa caaacaacat
     6301 ggtcaaatct caaccgattt tgagatatat cttgcgcggg atccccgcga ttgcagtagc
     6361 ggttctgctt tctgcatgta gtgcaaataa caccgcaaag aatatgcatc ctgagacacg
     6421 tgcagtgggt agtgaaacat catcactgca agcttctcag gatgaatttg aaaacctggt
     6481 tcgtaatgtc gacgtaaaat cgcgaattat ggatcagtat gctgactgga aaggcgtacg
     6541 ctatcgtctg ggcggcagca ctaaaaaagg tatcgattgt tctggtttcg tacagcgtac
     6601 attccgtgag caatttggct tagaacttcc gcgttcgact tatgaacagc aggaaatggg
     6661 taaatctgtt tcccgcagta atttgcgtac gggtgattta gttctgttcc gtgccggttc
     6721 aacgggacgc catgtcggta tttatatcgg caacaaccag tttgtccatg cttccaccag
     6781 cagtggtgtt attatttcca gcatgaatga accatactgg aagaagcgtt acaacgaagc
     6841 acgccgggtt ctcagccgca gctaataaac cgtttggatg caatcccttg gctatcctga
     6901 cgagttaact gaaagcactg cttaggcagt gcttttttgt tttcattcat cagagaaaat
     6961 gatgtttccg cgtcttgatc caggctatag tccggtcatt gttatctttt aaatgttgtc
     7021 gtaatttcag gaaattaacg gaatcatgtt tatacgcgct cccaattctg gacgtaagct
     7081 cctgcttacc tgcattgttg caggcgtgat gattgcgata ctggtgagct gccttcagtt
     7141 tttagtggcc tggcataagc acgaagtcaa atacgacaca ctgattaccg acgtacaaaa
     7201 gtatctcgat acctattttg ccgaccttaa atccactact gaccggctcc agccgctgac
     7261 cttagatacc tgccagcagg ctaaccccga actgaccgcc cgcgcggcgt ttagcatgaa
     7321 tgttcgtacg tttgtgctgg taaaagataa aaaaacattc tgttcatctg caactggtga
     7381 gatggacatt ccactcaatg aattgattcc ggcgctcgac attaataaaa acgtcgatat
     7441 ggcgatctta cccggcacgc cgatggtgcc gaacaaaccc gcaatcgtca tctggtatcg
     7501 caaccctttg ctgaaaaata gcggcgtgtt tgccgctctg aatctcaacc tgacgccttc
     7561 actcttttat agttcacggc aggaagatta cgatggcctc gccctcatta ttggtaatac
     7621 tgcgctatct accttttctt cacgtttgat gaacgttaat gaattaaccg acatgccggt
     7681 ccgtgaaact aaaattgcgg gcattcctct gaccgttcgg ctttatgcag atgactggac
     7741 atggaacgat gtgtggtacg catttttact gggtggcatg agtggaactt tcgttggact
     7801 tctctgctat tacctgatga gtgtgcgtat gcgcccaggc agagaaatca tgaccgccat
     7861 caagcgcgaa caattttacg tggtatatca accggtggtt gatacacaag ctttgcgggt
     7921 aacgggcctg gaagtactgc tacgctggcg gcatcctgta gcaggagaaa tacccccgga
     7981 tgccttcatt aactttgccg aagcgcaaaa gatgattgtg ccactgactc agcacctgtt
     8041 tgagttgatt gcccgcgatg ccgcagaatt agaaaaagta ctgccggtag gcgtcaaatt
     8101 tggcattaac attgcgccgg cccacttgca cagcgaaagc tttaaagcgg atatccagaa
     8161 actgctcact tccctgcccg cacaccattt ccagattgtg ctggaaatta ccgagcgcga
     8221 tatgctgaaa gagcgagaag ccacacaact cttcgcctgg ctgcattcgg tcggcgtaga
     8281 aatcgctatt gatgacttcg gcaccgggca cagcgcgctt atctatcttg agcgttttac
     8341 gctcgattat ctgaaaattg atcgtggatt tatcaacgcc atcggt
//
LOCUS       DAPOXO010000146         8333 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.146, whole genome shotgun sequence.
ACCESSION   DAPOXO010000146 DAPOXO010000000
VERSION     DAPOXO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8333
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.146"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(123..887)
                     /locus_tag="ROH59_004722"
     CDS             complement(123..887)
                     /locus_tag="ROH59_004722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDX4807113.1"
                     /translation="MNNQTIRTSVPALDKTVRVCNYLFSSPGATFSQIQQDLDLPKSS
                     TSSLLNALVEHHLLRQERGRFFLGLKLYEWGNRSLEQFDISKVARPVLEKLRDSTDLI
                     CHLGILDEVAPIYILKLESTQPIGIRTWVGKKLPLHSSGVGKALCAWLPQDVIDTLLP
                     EETLPRFTQTTITRKSDLIQEFARIRERGWAFDNAEDSPGIYCIAAPVFNQTREVIAA
                     ISISGVEIQIPKEKIEYYSTLVLDACQELSEKLKYI"
     gene            1127..2026
                     /locus_tag="ROH59_004723"
     CDS             1127..2026
                     /locus_tag="ROH59_004723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDX4807114.1"
                     /translation="MLTAFRGIFPPVPTIVDAQGKLDKAGMARMIDHVLENGANGMLI
                     LGSGGEFSQFSSQQRKEIAAFCLSHVDGKVPVLVGIACAGTAETIDLGHHAQEHGADG
                     VMVVNPYYAKLSDDARFMHYKSIADSLKIPVFLYNFPDLTGQDIGLEVITRLAREVPN
                     IVGIKDTIDNISHTREVINRVHAFRPDFIIFSGYDEYMLDTLLLGGHGGIPATFNFAP
                     NITRGIYQAVMENDLDKARYFQQQLAKLSPLYTLEQPFFGVIKTAIKLSGLDISTAVM
                     APALPLSDDKVARVKAILEHIHQ"
     gene            2043..3560
                     /locus_tag="ROH59_004724"
     CDS             2043..3560
                     /locus_tag="ROH59_004724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDX4807115.1"
                     /translation="MNKTPILKLNNSDDVVIARTELPAGSWLESESMETRDLIPAGHK
                     IALRDIPAGSAVKRYGQIIGFATRDIRQGEHIHVHNLGMGSFERDYAWGIDSHLPEKD
                     VHQDTFMGIRRKDGRVATRNYIGVLSSVNCSATVVRAIEDHFRTRGLSDYPNVDGIVA
                     LPQSFGCAFGSDSEMMKVMRRTMAGYATHANFAGIVIVGLGCESFQIKDMMNAHGLHE
                     SPVFHTMTIQESGGTRNAIEKGISFILDMLPEANNVKREPVPVSEIILALECGGSDSY
                     SGISANPALGYAVDRLVRQGGTAILSETSEIYGAEHLLTRRAISREVGEKLIRRIKWW
                     EEYCKRTGSEMNNNPSAGNKAGGLTTVLEKSLGGIAKAGTTSLMDVYEYAEPVTAKGL
                     VFMDTPGYDPMAVTGQIAGGANLLCFTTGRGSAFGAKPTPCLKLSTNNALWQRQRDDM
                     DLNCGTIVDGEETIEQVGERIYQRIIELASGHRSRSEELGYGSQEFVPWIMNSIM"
     gene            3638..4651
                     /locus_tag="ROH59_004725"
     CDS             3638..4651
                     /locus_tag="ROH59_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HDX4807116.1"
                     /translation="MERKPVLGIFLGEAAGIGPELVAKVVADGTVYKYCRPVLIGDAR
                     VLALGQKIAGVHFQWNVISDPTEADWTTGNVPLLDLKNFNPEKLTMGTIDTDSGYATG
                     ESLVTCMSLLKSGKIDGFVFAPLNKEAFKKGGWDIEDEHYLFAEQLGYLDKPRGLLNV
                     LGDLWVFRVTGHIPFKDIASHITPENVSRSIQLCYDTLRMAAVENPRIAVAALNPHAG
                     DGGTCGKEEIDVLIPVIEGFREKGMDMYGPVPGDTVFIHAFNHEYDAVVTLFHDQGQI
                     ATKLHSFDVGITVAAGLPFAITTPEHGTAFDIAGKGIAKTLATERAIAVAARMASTVH
                     KDN"
     gene            4912..6156
                     /locus_tag="ROH59_004726"
     CDS             4912..6156
                     /locus_tag="ROH59_004726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX4807117.1"
                     /translation="MLQIKARTKILALFCAMSFLMYVDRVNLSATAGLIKDELGLSNT
                     ELGVIFSAFAYTYAVFQIIGGWFVDRLGSRRMIIFCGIIWVIATMATGFVGGFISLFL
                     ARLLLGVGEGAALPSQARAITYWFKPQQRGFVQGVTHSFSRLGNAITPPIIVALVAFW
                     SWRGAFISLAIVTFIWLISWIISYKDDPRDHSGMTEEELEGVPIFEKKDLKVKAEPTP
                     WRALIKRMGPTMGVYFCYGWTSWLFFTWLPTFFMHGRGMDLKSSALFTAGVFLSGVVG
                     NTVGGVISDKVLKMTGNLVAARRNVILFSFISVLFLLVPVINTDSLLIMTICLSVAFF
                     CLELTIGPIWAVPMDITPKYVGIASGLMNAGSAVAGIISPIVFGIIIDKTGNWSLPFY
                     GSVALLIIGIFLTFFMRPDKSL"
     gene            6244..6494
                     /locus_tag="ROH59_004727"
                     /pseudo
     CDS             6244..6494
                     /locus_tag="ROH59_004727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            6773..7648
                     /locus_tag="ROH59_004728"
                     /pseudo
     CDS             6773..7648
                     /locus_tag="ROH59_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011815933.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            complement(7848..8084)
                     /locus_tag="ROH59_004729"
     CDS             complement(7848..8084)
                     /locus_tag="ROH59_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX4807118.1"
                     /translation="MVKLALQPRDSVACIAREHDINDNLLFKWLRLWLIKGRISRRLP
                     VTNSSGIGVELLPVEMTLDERPYPVFTRGNYEDQ"
BASE COUNT         2226 a         1745 c         1967 g         2395 t
ORIGIN      
        1 gcttaaaaag aaaaacactc tctttgttat atacgtactc tgataaatgc cagataaaac
       61 tattaatttt cataaaaata taataccata tattatgatg ctatacatct tacatattca
      121 attcagatat attttaattt ttccgatagt tcttgacacg catcaagaac caaagttgaa
      181 taatattcaa ttttttcttt aggtatctga atttccacgc cactaatgct gatagctgca
      241 attacttcac gagtctgatt aaataccgga gcagcaatac aataaattcc cggtgaatcc
      301 tctgcgttat caaaagccca tccacgttca cgaatacgtg caaattcctg tattagatca
      361 gatttacgag tgatagttgt ttgcgtaaat cgtggcaacg tttcctcagg caacaatgtg
      421 tcaatgacgt cttgaggtaa ccacgcacat aaagccttac caactccaga actatggagt
      481 ggcaacttct tgcctaccca cgttctgatg ccaattggtt gtgtactctc gagtttcaaa
      541 atatagattg gagcgacttc atcgagaatg cccagatggc agataagatc agtactgtct
      601 ctcagttttt ctagaaccgg cctcgctacc ttactgatgt caaactgctc cagagatcga
      661 ttcccccatt catacaattt cagcccaaga aaaaaacgcc ctctttcctg acgtaacaga
      721 tgatgttcga caagggcatt cagtaaagat gatgtgctgc tttttggcag atccagatcc
      781 tgctggatct ggctgaaggt ggcgcctgga gagctaaaaa ggtaattgca gactctgaca
      841 gttttatcga gtgctggtac cgatgttctg atggtttgat tattcataaa aaaatatgat
      901 tccttacaat actgaatagt ataccccatt cccccttgat gcgcagcggc gcttagcaca
      961 catattatac atggcctccg cgtaccggca tgcctctata aacctgactt atttcacact
     1021 tttcatatcg cattgtaaaa acatttgaca tgcaaaacct gaatttgatt cactttattc
     1081 agcataaaga acttgtgttc catatacaga acttagtgag agtgatatgt tgacagcgtt
     1141 tagaggtatt ttcccgccag ttcctacaat tgttgacgca caagggaaac tagataaggc
     1201 tggcatggcc aggatgatcg accatgtttt agaaaatggt gcaaacggga tgttgatcct
     1261 tggcagtggg ggagaattct cacaattttc ttcccagcaa cgaaaagaga tagctgcatt
     1321 ttgcttaagt catgtagatg gcaaagtgcc tgttctggtg gggatcgcct gcgcgggaac
     1381 tgcagaaact attgatttag gacatcatgc acaggagcac ggagctgatg gtgtgatggt
     1441 ggtgaatccg tattatgcaa aactcagcga tgatgcccgg tttatgcatt acaaatctat
     1501 tgccgattca cttaaaattc cagtgtttct ctataacttt cctgatctga ccggtcagga
     1561 tattgggctt gaggtcatta cccggctggc ccgggaagtt ccaaatatcg tgggtatcaa
     1621 ggataccatc gataatatca gccatacccg ggaagtcatc aaccgtgtac atgcttttcg
     1681 tccggatttc attatattca gcggatatga cgaatatatg ctggataccc tgttactggg
     1741 cggccatggt ggtattccgg cgacattcaa ttttgctcca aatatcacac gtggtattta
     1801 tcaggccgtt atggaaaatg atcttgataa agcgcgttat tttcagcaac aactggcaaa
     1861 actgtctccg ttatacacac tggagcagcc tttctttggc gtgataaaaa ctgccatcaa
     1921 actgagtgga ctggacatat ctactgcagt tatggcaccg gctcttccgc tcagtgatga
     1981 caaggtcgcc agggtgaaag ccattctgga acacattcac cagtgattac gaggatcgta
     2041 agatgaataa gactccgata ctcaaattaa ataactcgga tgatgtcgtt attgccagga
     2101 cagaacttcc tgccggaagc tggctggaat ctgaaagtat ggaaacacgt gaccttattc
     2161 cggcagggca caaaattgct cttcgggata ttccggccgg cagtgccgtt aaacgctatg
     2221 gacagataat cggttttgcg acccgtgaca tccgacaggg cgaacatatt catgtgcata
     2281 atctcggtat ggggagtttt gagcgtgatt atgcctgggg gatagacagt catcttccgg
     2341 aaaaggatgt tcatcaggat acctttatgg ggatccgcag aaaagacgga cgggtggcaa
     2401 cccgtaatta tattggtgta ctgagttctg taaactgtag tgcaaccgta gtaagggcaa
     2461 ttgaagatca tttccgtacc cgtggtctca gtgattaccc taatgtggat ggtattgttg
     2521 ccctcccaca aagttttggt tgtgcctttg gctctgacag cgaaatgatg aaagtcatgc
     2581 ggaggacaat ggcaggctat gccacgcacg cgaactttgc cgggatcgtg atcgtgggac
     2641 tgggatgtga atcattccag attaaggaca tgatgaatgc ccacggatta catgaaagtc
     2701 ctgtattcca tacaatgact attcaggaaa gcggcggaac acgtaacgct atagaaaaag
     2761 gtatttcctt cattctcgac atgctcccgg aagccaacaa tgtcaaacga gaaccagttc
     2821 cggtatcaga aatcattctg gctcttgagt gtggcggctc tgatagctat tcaggaattt
     2881 ccgctaatcc ggctctcggg tacgcagttg atcgcctggt tcgccaggga ggaacggcta
     2941 ttctgtcgga aacatcggaa atttatggag cagaacacct tctgacacgc cgtgccatta
     3001 gtcgcgaagt tggcgagaaa ctaatccgca gaattaagtg gtgggaagag tactgtaaac
     3061 gtacagggag tgaaatgaat aacaaccctt ctgcaggtaa taaagcgggg ggactgacca
     3121 ctgttctgga gaaatcgctg ggagggatag caaaagctgg tacaaccagc ttaatggatg
     3181 tgtatgaata tgctgaaccg gtgacagcaa aagggcttgt ctttatggat acccccggat
     3241 atgacccgat ggcagtaacc ggacaaatcg ccggaggagc caacctgctg tgttttacca
     3301 cgggcagggg atctgccttt ggcgcaaaac ccactccttg tctgaaactg tcaaccaata
     3361 acgcactatg gcaacggcag cgcgacgaca tggatttaaa ctgtggcacg attgttgatg
     3421 gcgaagaaac aatagaacag gttggagaac gtatttatca gagaattatt gagctggctt
     3481 caggtcatcg tagtcgaagt gaagagctgg gttatgggag ccaggaattc gttccttgga
     3541 taatgaactc aatcatgtaa taactacggg cataatttgt tttgcccgga aataaggaaa
     3601 caaactgaat cctgtttttg ataattagag gtgaataatg gaacgtaaac cagtactggg
     3661 cattttttta ggtgaagctg ccggcattgg acctgaactg gttgccaaag tcgtagctga
     3721 tggtactgtc tataaatatt gcagacctgt tctgattggc gatgcccggg tacttgctct
     3781 tggacaaaag attgctggtg tgcattttca gtggaatgtc atcagtgatc ccactgaagc
     3841 tgactggact acgggaaatg taccattact tgatttgaaa aattttaatc ccgaaaaact
     3901 aactatgggc accattgata ccgactcagg ttatgcaaca ggagaatcac tggtaacctg
     3961 tatgtcatta cttaaatcag gtaaaattga cggttttgtc ttcgctccac tcaataaaga
     4021 agctttcaag aaggggggct gggatattga ggacgaacat tatctctttg ctgagcagtt
     4081 aggatatttg gataaacctc gtggcctgtt gaatgtcctt ggtgacctct gggtttttcg
     4141 cgtgacggga catattccat tcaaagatat tgccagccat attacaccag aaaatgtcag
     4201 tcgttcgatt cagttatgct atgacacatt acgtatggcg gccgttgaaa atccacgaat
     4261 agcggttgca gcacttaatc ctcatgccgg tgatggagga acctgtggta aggaagaaat
     4321 tgatgttctc attccggtca ttgaaggctt ccgcgagaaa gggatggata tgtatggccc
     4381 agtaccgggt gatactgttt ttattcatgc atttaatcat gaatatgatg ctgtcgttac
     4441 cctgttccat gaccagggac agattgccac caagcttcat tcctttgatg tgggcataac
     4501 tgtagccgca gggcttccat ttgctattac aacaccggaa catggcactg catttgatat
     4561 tgcaggcaag ggaatagcaa aaactctggc cacagagcgg gctattgcag ttgcagctag
     4621 aatggcatct acagtgcata aagataattg agatctctaa atcttagtgt atttatatat
     4681 tcttttttga ttttattgaa tgaagttatt tttatgttat tccgccttag ccataagcca
     4741 tggttaaagc ggaataacaa gccaaaaagc gtccctcgaa gcacgttgaa ccgtattatt
     4801 tataattatg gtttacagag taaaaaaata gatgaatgtt ggggcgttgc taatatatgt
     4861 aactaattga cattatttac tagcaattta acgctagttt aggagacaaa aatgttacaa
     4921 ataaaagcca gaaccaagat acttgcgcta ttttgcgcaa tgtcattcct aatgtatgtg
     4981 gaccgagtaa acttatcagc tactgcgggg ttgattaaag atgaactcgg actgagtaat
     5041 acagaactcg gcgttatttt ttctgctttt gcttatacct atgcagtttt tcaaatcatc
     5101 ggtggctggt tcgttgatcg acttggctca cgccgcatga tcattttttg tggcattatt
     5161 tgggttatag caaccatggc gactggtttc gtcggtggct ttatatcact attcctcgcc
     5221 agattgctat taggtgtagg ggaaggtgcg gcgctgcctt ctcaggcgcg agcgatcacc
     5281 tactggttca agccgcagca gcgtggcttt gttcagggcg ttacgcactc attctctcgt
     5341 ttgggaaatg cgattactcc ccccattatt gttgcattag tggcattttg gtcttggcgt
     5401 ggcgcattta tcagtttggc tattgtcaca tttatctggt taatatcttg gatcatatcg
     5461 tataaagatg acccacgaga ccacagcggt atgaccgaag aagaactaga aggcgtacca
     5521 attttcgaga aaaaagatct aaaagttaaa gctgagccta ctccatggag agccctgata
     5581 aaacgaatgg gaccgacaat gggagtttat ttctgttacg gatggacaag ttggttgttt
     5641 tttacttggt taccaacttt ctttatgcat ggtcgcggca tggatcttaa gtcatcggcg
     5701 ctctttactg ccggcgtatt tctgtccggt gtagtaggta atacggttgg tggcgtaatc
     5761 agcgacaaag tgctgaagat gactggcaat ctagtagcag cccggcgtaa cgtcattctt
     5821 ttcagcttta tctccgtact atttctgctc gtcccggtta taaatactga ctcgttgctc
     5881 attatgacta tatgtctgag tgtggcgttc ttctgtcttg agttgaccat agggcctatc
     5941 tgggccgtcc cgatggatat tacgccgaag tatgtgggaa ttgccagcgg attgatgaac
     6001 gccggttccg ctgtcgccgg cattatttca cctatcgtct ttggcatcat tatcgacaaa
     6061 acaggcaact ggagtttacc attctacggt tccgtcgcat tgcttattat tggtatattt
     6121 ctgacgttct tcatgcgtcc agataagtca ttgtaaaagt cgaattcagg gctgaagtgg
     6181 tctactgaat ttggccatct gaacagggtg atatgctcac cttagaacaa cacaggtgca
     6241 cctatgaaaa gaagaaattt cagtcctgaa ttcaaacgtg aatccgctca gttggttgtc
     6301 gatcaaaatt acactgtttc tgacgctgct aaggctatgg atgttggtct ttccacgatg
     6361 acggaatggt tcaaacaact gcgtgatgag cgtcagggta aacgccaaaa gcctccctga
     6421 taacaccgga acaaatcaaa ctacgtgagc taaagaaaaa gctacaacga attgaaatgg
     6481 aaaacgaaat attaaaaaac tttccatgtg tgaaaccccg tcccgagtct cagaaactcc
     6541 ccggtaaaac tggcagtcta atatagcgaa ggaagcagcc gtcgaccttt tggtggtatg
     6601 acccttaaaa aacatggttc agggagtgtg gcggatccga cagtggtagc ttgatcccgt
     6661 tcaggaaggt gatttctccg tcgtctcctc cttcgttcat taaaaatgag caaggagatt
     6721 tatatgaaaa aatcctcccg aatgtctatt gtccattctc atgctgcggg cgttgtttat
     6781 gtcgatgatg gtagcggtaa ttctggcaac agcaggcatg accggcatta cgcttatagc
     6841 cgttggctct ttggttgttg gcgtggcaat ggtctttttc ccggctattg ctcatccgta
     6901 catgaagaaa gtgaccggtt ctgatgacgt tgccatcggc cacttctcaa cattatctta
     6961 tgtattggcc ggtttcatcg gcagcaagtt tggtaataaa gagcactcga ctgaagacat
     7021 gaatgtgccg aaaagtctgc tgttcttgcg cgacacgccg gttgctatct cttttaccat
     7081 gatcataatt ttcctgctga cgtgcctgtt tgcgggtgca gatgcggtga aagagcttag
     7141 cggtggtaaa aactggttca tgttctctat catgcaatcc attaccttcg cagctggcgt
     7201 gtacatcatt ctgcagggtg tgcgcatggt gattgcggag attgtcccgg cattcaaagg
     7261 tatttcagac aagctggttc cgaatgccag acctgctctc gattgcccgg tcatcttccc
     7321 ttacgcacct aacgctgtac tggttggttt cctgagtagc tttgctgcag gtttaatcgg
     7381 tatgttcacg ttgtatctgc tgaacatgat cgtgattatt cctggtgtgg tgccgcactt
     7441 cttcgtaggt gcagctgcag gggtattcgg taatgcaacg ggtggacgtc gtggtgcgat
     7501 tttgggtgcc tttgcgcaag gcttgcttat taccttcctg tcagtattct tattgcctgt
     7561 gctgggtgat attggttttg ctaacaccac cttcagtgat gctgactttg gcgcactggg
     7621 tattttgtta gggattatcg ttcgctaata ttttgatgac attaatatcc tccaggattt
     7681 caggaacgtg gaggatatta attcctctta ttttctccat ttttctttct tccagttagg
     7741 actgcatctg attaatcgta agcgctccga gaagtacgta gcgtaaggat tattttacag
     7801 ctgagaagtt tcagtacagc agttcatgca cacggttcga cggctagtca ttgatcttca
     7861 taattacctc gcgtaaaaac ggggtaaggc cgctcatcca gcgtcatctc cacaggtaat
     7921 aattcaacgc caatgccaga agagttcgtt accggaagac gccgtgatat acgccctttg
     7981 atcagccaga gcctgagcca tttgaacaga agattatcat tgatatcgtg ctcccgggca
     8041 atacaggcaa cagaatccct tggttgtaaa gccagtttaa ccatttgaag tttaaactca
     8101 tttgaaaatg acctgcgggg ttctgctgat aatgtttttt gttctataac aggtgtccac
     8161 ttgttgaaaa ggtgggtacc tatgttacca atacaggctt aatggctaca tacagcagtc
     8221 ggtttacgca tacactttta tagtgcactc cggcctcatg aatataacgg tggattaccg
     8281 ccgaacgaat cggaaaatag atactggaaa aaatctgaaa ttgtgaccag ttt
//
LOCUS       DAPOXO010000147         8314 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.147, whole genome shotgun sequence.
ACCESSION   DAPOXO010000147 DAPOXO010000000
VERSION     DAPOXO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8314
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.147"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..677)
                     /locus_tag="ROH59_004730"
     CDS             complement(<1..677)
                     /locus_tag="ROH59_004730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7726 family protein"
                     /protein_id="HDX4807119.1"
                     /translation="MSHNKKEYAKFFRRPIFSSLAKGKDISDLFGSFDSYCYETLFSN
                     NDNNEHEISLRDLFTSLYDFLRLNYRNEYVYKTALVNKIIFGKHSPKTSSSSIELPIK
                     NSIVDVAVFNGTSTAYEIKTEYDSPKRLITQAPDYLDVFDKVYIVTHPEYASKYCALN
                     LPRVGVMVLNKKDQLSVIKEADSNIDYIKSDSLFSVLRKEEFLAIIEDYTSTKINMPN
                     GLVYEYC"
     gene            complement(1357..1629)
                     /locus_tag="ROH59_004731"
     CDS             complement(1357..1629)
                     /locus_tag="ROH59_004731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HDX4807120.1"
                     /translation="MKMMRMYCPTCQAVARIGKTNRKHPQLYDVYCYCSNVECGHSFV
                     MNVAFSHSVSPSALNGQGRVKELIDAIPPEEREKALKLLLAAQKNG"
     gene            complement(1912..4599)
                     /locus_tag="ROH59_004732"
     CDS             complement(1912..4599)
                     /locus_tag="ROH59_004732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HDX4807121.1"
                     /translation="MKTPSVSTISGAAIGRWPYILSALGIKVPSAGHHGACPACGGKD
                     RFRLDDKAGRGTWFCNQCGHGDGLDLVRLVTGRKIKEVAGMVSEALALPEIQEKPALP
                     ARKKAAGKEAGAERYTRLRQQSCNGEPVYLTNKSLHGYSLPLLSQPLNLAGITFSTGS
                     LLLPLTDISGNITGGQLINPDGDKSLLPGSQLSGAFIALTDIPAETPEQVIITEGFAT
                     ALTVSLLTEGWIVAAVAATNLLKVTEQIRKRWPETRIILAGDNDLADGKENTGRIQAE
                     KAAKAVDGWVTLPPVRHKADWDDYRQEVGKERARDAFREEMTLHGKGQTRLPEGFRLT
                     KEYLWYDKLVNKSDGDTEIRNIKICSPLRVTAITSDADGSNYGRLLEWEDTNGNSRKW
                     AMPMEMLGGSGEELRRVLLVNGLSYININGMARAFLMEYISLCKPDRKVTCVNKTGWH
                     GGVYVLQDEVIGREAQSVILQTSSVQGRDFRVSGTSEGWRENIGRYCIKNARLAFAVS
                     LAFAAPLLKLVGIGGGGYHLKGESTDGKTTTMKVAASVCGGTDFWHTWRATGNALEGT
                     ASRRNDATLMLDEIREVDGREAGNIAYMLANGQGKARARTDGSVRETNRWNLLFLSTG
                     ELSLVEHAASAGERTYAGVEVRMIQIPSDSGKYGVFEELHGFSSGKTLAEHLEQHVAH
                     YHGAPFRDWLYCLTADLPELTSQAKALLKEYTRRLTPENAGNQVGRAVTRFALVAMAG
                     ELATKAGITGWPEGEAFRAAQSCLAAWMADRGHTANQEDKAALEQVRDFMTRNQFSRF
                     ADWNDDRNRPVSMMGFRKVDKGDNVTEPVVTFYVLPSGWKEICKGFDSRKVARLCVDA
                     GWLKPGEDGRTQNSIRLPEIGLKRVYQFNTQVLGSAEPE"
     gene            complement(4596..5006)
                     /locus_tag="ROH59_004733"
     CDS             complement(4596..5006)
                     /locus_tag="ROH59_004733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807122.1"
                     /translation="MNNNQNLKAHALRTAVLRYYIADAFISLMVRVHNEPVYIEDGER
                     IELSHEKVVSNIIYHIEMPWVNEFGADAGCILAAEKLEKMLKPGFMSENIRLSVFGVT
                     EMREVYRDIIFGAPDGELPEGFEFVKPEGQEVLL"
     gene            complement(4999..5235)
                     /locus_tag="ROH59_004734"
     CDS             complement(4999..5235)
                     /locus_tag="ROH59_004734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807123.1"
                     /translation="MKSMNFKQGCILSEQGESRLLRAALASEFLAEVLSVPTVNGART
                     VSAEGAAALVACIAEQLDGVVKETSTIKGVMRDE"
     gene            complement(5232..5822)
                     /locus_tag="ROH59_004735"
     CDS             complement(5232..5822)
                     /locus_tag="ROH59_004735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HDX4807124.1"
                     /translation="MPALINPGNDQFSVINFLPHQECAGYSLKVAAKSAAGRRNPCYL
                     KAILHALGVFFCVAALTHLKFMVWWLIVFFYFLRHIIRIMVVQAGQLSGWPVSFRAGI
                     PTPVWATTHERRNSGGSVTRYLKEVAIMATVPALSHPEFTFVFLAVRRTDRDARPRPV
                     RVIAECEHAARLKLATEFILSFAARIPVKRAGEVVA"
     gene            complement(5910..6914)
                     /locus_tag="ROH59_004736"
     CDS             complement(5910..6914)
                     /locus_tag="ROH59_004736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006762596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P2 family phage major capsid protein"
                     /protein_id="HDX4807125.1"
                     /translation="MYAFKTERPDAARRYHNKFVTGTNYQEESNRRFALSEPTENILR
                     TSILESGWLIKNITLRDVNAVSGNAVNIGASELYTGRVDGGRFHKKMAINGTEFFLTE
                     TDTCARISYSDMSHIYHTGVPDEFEKTVESFFAQAYALDMLRVGFNGVSIANTTNPEI
                     NKKGEDVNIGWHALAKAYGNGKQIISEPVTLGETGTWKNIDALANHLITELIAEQFRE
                     DPRLVVLVGAELAAHQRLKLFNAADRPSDVNAAQMATSSVAGRFAFIPPFMPGKRLAV
                     TTLDNLHIYTQAITRWFRAEFDDESSEYVHSYLRNEGYALGEPELYAAVDECTLTFAD
                     "
     gene            complement(6937..7797)
                     /locus_tag="ROH59_004737"
     CDS             complement(6937..7797)
                     /locus_tag="ROH59_004737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807126.1"
                     /translation="MVDNVFKKKLASIKNEHVSVLDSYKVRSFKETHSDTACIVRIIE
                     IYSLNKLRAKGEKLYSLTGLTVPDTETVANEINLLLSRYAQLCRQEEEELSFRQREVT
                     NAEVAWKSTFSKNGVSSIAEAKTNKMGHAERADAERYYHLAVSRLNEQHSRLSTIKLL
                     PGVLADEGNYIGKGIDKRLLNIFPQSGQIPADFISVFNDSDVVRDIKFITDALKSLSD
                     SVSEIISRCSVPTDRYVLNNGGMARAMAYREYYRADNYVLRSVVSDRDYVEHVMKYNL
                     VTEYKNKIFS"
     gene            complement(7815..8042)
                     /locus_tag="ROH59_004738"
     CDS             complement(7815..8042)
                     /locus_tag="ROH59_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDX4807127.1"
                     /translation="MSLLPRENAPQKRYRLLRISEVINLTGLPKSTIYLKIKNDEFPN
                     QVSIGSRSVAWVEHEVNEWIEKNILNRKLNS"
BASE COUNT         2203 a         2142 c         1659 g         2310 t
ORIGIN      
        1 ttacaatatt cataaaccaa tccgttaggc atatttattt tagttgaagt gtaatcttct
       61 attatagcta agaactcttc ctttctaaga actgaaaaca agctgtcact tttaatataa
      121 tcaatatttg aatctgcctc cttaatgaca ctcaattgat cttttttatt caaaaccata
      181 actcccactc tggggagatt taaagcacaa tatttacttg catactctgg atgtgtaact
      241 atatacactt tatcaaaaac atccaaataa tcaggggctt gagtaatcaa cctttttggt
      301 gaatcatact ctgtcttaat ctcgtaagct gtagacgtac cattaaacac cgcaacatcc
      361 actatagagt ttttaattgg taactctatg gacgacgaac ttgtttttgg gctgtgctta
      421 ccgaatatta ttttattgac aagtgctgtc ttataaacat attcatttct ataattcaga
      481 cgcaaaaaat catataatga tgtaaataaa tcccttagtg aaatctcatg ttcattatta
      541 tcattgtttg aaaacagtgt ttcatagcag taagaatcaa aactcccaaa taaatccgaa
      601 atatccttac cttttgctaa ggatgaaaaa atggggcgac ggaaaaattt agcatattcc
      661 tttttattat gactcattac tcatactcta taaacatcat gcaatttgat aagttatgac
      721 gaattctcac catccagtta ctacctgtac atactaatca aaaaaaacga gtacgcaaga
      781 tacgaaagta cttttcttgt tcaccagtta gcttaccttg atcctcacca gcgactggaa
      841 gataggtagc agtatatgtg gaaaccttcc cctagctagg tctacaaacg tagtttgggc
      901 atttaggctc cacgattcac ggtttgacac ggcctgatat ctgcacattc gttttgatat
      961 gcagcaatcg tgaaaaagga aaatatacgc tcgacagacc aaaacggcac tacaccgcac
     1021 ccgcctgcgg ttttcatatc actaaaaatt ttcagcctgg attttttaca aacgataccg
     1081 ccagtccgtg ccagtcctcg agatgtactg cgatacagga actgaaaaga atgaaaagaa
     1141 attcattttt tttcagtttt actgtccgtc gaatctatgg cctgaatacg caactctatg
     1201 atattaaatg gataattaat tttaggtgtg tgattttatg aaggtttgtg aaacatgaag
     1261 aagataacca gttgaaaaat aataatttta tgaccgtata aactgaaatc ctgtgttcag
     1321 gttccgggaa cagatcggcc attcccgacg catactttac ccattctttt gcgcagccag
     1381 cagcaacttt aaagcctttt cccgttcctc gggtggaatt gcatcaatca gctctttaac
     1441 ccttccctgc ccgttcagcg cgcttggact aacggaatgg gagaaagcaa cattcatcac
     1501 aaacgagtga ccgcactcca cattagagca atagcagtac acatcgtaca gttgtgggtg
     1561 tttcctgttt gttttaccta tccgtgctac tgcctgacat gtggggcagt acattctcat
     1621 catcttcatc gttctgtgcc ctatactgtt gcccgccaga agaagggatt tggatcccta
     1681 cctcttgttc tgaacgtgta acactggtaa cacgtgtaac gctattgatt taaaaggatt
     1741 taatctgtta ccagttagca aaatcaagag gtaacgcgtg gtaacacacc attttttgtt
     1801 acctctgtta ccagtcagta tttttgactg gtaacactga agaaccgcat cagtaacggg
     1861 tgttacctct gttaccagtg ttacctcata aaaataagac tcacgcgata atcactcagg
     1921 ttcagcgctt cccagtacct gtgtattgaa ctggtacaca cgtttaagcc ctatttctgg
     1981 caggcgaatg ctgttttgcg tccggccatc ttcaccgggt ttcagccagc ccgcgtccac
     2041 acacaacctg gccaccttac gcgagtcaaa tcccttacag atctccttcc agcctgacgg
     2101 gagaacgtag aacgtcacaa ccggctctgt cacgttgtct cctttatcga cttttctgaa
     2161 tcccatcatt gaaacaggcc ggttcctgtc gtcattccag tcagcaaacc gactgaactg
     2221 attacgcgtc atgaagtccc gaacctgttc aagtgccgct ttatcttcct gattagctgt
     2281 atggccccgg tcagccatcc atgcagccag acagctttga gcggcacgaa aggcctctcc
     2341 ctccggccat cctgtgatgc ccgcttttgt ggccagctcc ccggccatcg caaccagagc
     2401 aaaacgggta acagcccggc caacctgatt cccggcattt tccggcgtca gccttcgggt
     2461 atactctttc aataaggctt tcgcctgact ggtcagttcc ggcagatcag cggtcaggca
     2521 atacagccag tcgcggaatg gtgcaccatg ataatgcgct acgtgctgct caagatgctc
     2581 agccagggtt ttcccgctac tgaagccatg aagttcttca aacacgccat acttgcccga
     2641 atcgcttggg atctggatca ttctgacctc aaccccggca tacgtacgtt ccccggcgct
     2701 tgccgcatgc tctaccagtg acagttcccc ggtagacaga aacaacagat tccagcggtt
     2761 ggtttccctt accgaaccat ctgttctggc tctggctttg ccctgcccgt tagccagcat
     2821 ataagcgata tttcccgcct ccctgccgtc aacctcccgg atttcatcca gcatcagcgt
     2881 ggcatcattg cggcggctcg ccgttccttc taaggcattc cccgtcgccc gccacgtatg
     2941 ccagaaatct gttccaccac atactgatgc agccactttc atcgtcgtgg ttttaccgtc
     3001 tgtggattcc cctttgaggt gataacctcc accgccgata ccaaccagtt tcagaagggg
     3061 ggcagcaaat gccagactca ccgcaaaggc aagacgggca ttctttatgc aataacggcc
     3121 tatattttca cgccagccct ctgatgtgcc gctgacacga aaatcacgcc cctgcacact
     3181 cgatgtttgt aagatgactg actgggcttc gcgccctatc acttcatcct ggagaacgta
     3241 aaccccgccg tgccagccag ttttattcac acaggttact tttctgtccg gtttacacag
     3301 cgagatatat tccatcagga atgctctggc catgccgtta atgttgatgt aagaaagccc
     3361 gttaaccagc agaacgcggc gcagttcttc cccgctaccg cccagcatct ccatcggcat
     3421 tgcccattta cggctgtttc cgttggtatc ttcccattcc agcaaacgcc cgtaattact
     3481 tccatcagca tcactggtga ttgccgtcac ccgcaacgga ctgcaaattt tgatattacg
     3541 tatctctgta tcaccatcag acttattaac cagcttgtcg taccacaaat attcttttgt
     3601 cagccggaac ccttctggta aacgggtctg ccctttgcca tgcagcgtca tttcttcacg
     3661 aaaggcatct ctcgcccgtt ctttccccac ttcctgccga taatcatccc agtcagcctt
     3721 atggcgtacc ggagggagcg ttacccagcc atccaccgct ttggcggctt tctctgcctg
     3781 aatacgcccg gtgttttctt tgccgtcagc cagatcatta tctccggcca gaatgatccg
     3841 ggtttccggc cagcgttttc ggatctgctc cgtcaccttc agtaaattgg tggcagcgac
     3901 agccgccacg atccatcctt cagtcagcag actgacggta agcgccgtgg caaaaccctc
     3961 agtgataatc acctgttcag gtgtttcagc gggtatatcg gtcagggcaa tgaatgcgcc
     4021 agacagctgg ctaccgggca gcagactttt atccccgtca ggattgataa gctggccacc
     4081 agtaatattc ccggaaatat ccgtcaaagg cagcagtaat gaaccggtgg aaaatgttat
     4141 tccggccaga ttcaaaggct gtgacagcaa gggaagtgaa tacccgtgta agctcttatt
     4201 tgtcagatag accggctcac cattgcagga ctgctgtctg agtctggtat atcgctccgc
     4261 gcccgcttct tttcctgcgg cctttttcct ggctggcaat gcgggcttct cctgtatttc
     4321 tggtaatgca agcgcctcag ataccatccc ggcgacttct tttatctttc ttcctgtcac
     4381 cagacgaacc agatcaagac catcgccatg accgcactga ttacaaaacc acgtccctcg
     4441 ccccgcttta tcgtccagtc gaaaacgatc ttttccacca caggcagggc aagccccatg
     4501 atgtcctgcg gacggtactt taatacctaa tgctgacagg atataaggcc agcgcccaat
     4561 tgcagctccg gaaatcgtgg atacagacgg tgttttcaca gcagcacctc ctgaccttcc
     4621 ggcttcacaa attcaaaacc ttcgggtagt tcgccatcag gtgctccgaa aataatatcc
     4681 cggtaaacct cacgcatctc tgtgacacca aaaactgaca ggcgaatatt ttctgacata
     4741 aagcctggtt taagcatttt ttccagtttc tctgcggcca gtatgcaacc agcatcagcc
     4801 ccaaactcat tcacccacgg catttcaata tggtaaataa tattactcac cactttttcg
     4861 tgggagagtt ctattcgttc gccatcttca atataaacag gttcattatg aacacgcacc
     4921 attaaggaaa tgaatgcatc agcaatgtag tagcgtaaga ctgctgttcg taaagcatgc
     4981 gcctttaaat tttgattatt attcatcgcg catcactccc ttaattgtgc tggtttcctt
     5041 aacaacgcca tccagttgtt cggcaataca ggccactaaa gccgcagcgc cttccgctga
     5101 aacagttctc gctccattca ctgtgggcac ggacaagacc tctgcaagaa actcactggc
     5161 cagtgccgcc cgtaacagac gactctcccc ctgttcactc aatatgcagc cttgcttaaa
     5221 attcatggat ttcatgcaac cacctccccg gctcttttca cagggatacg ggcagcaaag
     5281 ctcaggataa attcagtggc aagtttaagg cgtgcagcat gctcgcattc tgcgattaca
     5341 cgcacagggc gtggacgggc atcacggtct gtacggcgga cagccagaaa gacaaaggta
     5401 aattcagggt gagataaagc agggactgta gccataatgg caacctcctt cagatagcgg
     5461 gtaacgctac caccggagtt cctacgctca tgggtggtag cccagacggg ggtaggaata
     5521 ccggctctga aggataccgg ccagcccgaa agctgccccg cctggactac cataattctg
     5581 atgatgtggc gtaaaaaata aaaaaataca atcagccacc acaccataaa ttttaggtga
     5641 gtcaaagctg cgacacaaaa aaacacgcct agcgcgtgta gtatcgcctt cagataacac
     5701 gggttcctac gcccggctgc cgattttgcg gcaaccttta aactatatcc cgcgcattcc
     5761 tggtgaggca agaaatttat aaccgaaaac tgatcattgc ctggattaat taacgctggc
     5821 atgcttaagc ctctgcttaa aaatagttct tcatttttcc tgatgctgta aacgagaccc
     5881 gcctctgagc gggtctttct gtcgctaagt caatccgcaa acgtcagggt gcactcatca
     5941 acagccgcgt acagttcagg ttcaccgagt gcataacctt cattgcgcag gtaggaatgc
     6001 acgtattcac tgctttcatc atcaaactca gcacgaaacc agcgtgttat cgcctgagtg
     6061 taaatatgca gattatccag cgtcgttact gccagacgct tacccggcat aaacggggga
     6121 ataaacgcaa agcggccagc aacagaactt gtagccatct gtgccgcatt cacatcagac
     6181 gggcggtctg cggcattaaa taacttcagg cgttgatgtg ctgccagctc tgccccaacc
     6241 agtacaacca gacgaggatc ttcacgaaac tgctcagcaa taagctctgt aatcagatgg
     6301 ttggccagag catcaatatt tttccaggtg ccagtctctc ccagagtgac aggctcagag
     6361 atgatttgct ttccgttccc gtaggctttc gccagtgcat gccagccaat attgacatcc
     6421 tcgccttttt tattgatttc cgggtttgta gtatttgcaa tcgacacacc gttgaaaccg
     6481 acccgcagca tgtccagcgc atatgcctgg gcaaaaaagc tctcaaccgt tttctcaaac
     6541 tcatccggca cgccggtatg gtaaatatga gacatatcgg aatagctgat ccgggcgcag
     6601 gtatccgtct ctgtcagaaa gaactccgta ccattgattg ccattttttt gtggaaacgg
     6661 ccaccatcca cacgtccggt atacagttca ctggcaccaa tattgacggc attacctgac
     6721 acggcgttaa catcacgtag ggtaatattt ttaataagcc acccggattc cagaattgag
     6781 gtacgcagta tattttcagt aggttcgctt aatgcaaagc gtctgtttga ttcttcctga
     6841 tagttagtgc cagtgacgaa tttattatga taacgacgtg ctgcgtccgg cctttcagtt
     6901 ttgaaggcat acatagtttt tcaccttttt aagtatttaa gaaaagattt tatttttgta
     6961 ctcagtaacc agattgtatt tcattacatg ctcaacataa tcccggtcac ttacgactga
     7021 acgtaataca taattatctg ctcgatagta ctccctgtaa gccatagctc ttgccattcc
     7081 accgttattt aatacataac gatcagttgg aacgctacaa cgactaataa tttcactcac
     7141 ggaatcagat aaagacttga gtgcatcagt aataaattta atatcacgga caacgtcact
     7201 gtcattaaat acagaaataa aatcagcagg gatctggccg gattgaggaa atatattcag
     7261 taaacgctta tcgattccct tcccaatgta gtttccttca tcggccagta ctcccggcaa
     7321 aagcttgatc gtgctcaatc gactatgttg ttcattcaac cgggaaacag ccagatggta
     7381 ataccgttca gcatccgctc gttcagcatg ccccatttta ttcgttttgg cttcagcaat
     7441 gctactgacg ccgttttttg agaatgtgct tttccatgca acttccgcat ttgtcacttc
     7501 acgctgccgg aaagataact cttcctcttc ctgacgacac aactgggcat aacggctcag
     7561 gagcaggttg atctcattcg ccacagtttc cgtatcaggt actgttaacc ccgtaagtga
     7621 atacagcttt tcacctttag ctcgcagctt attcagtgaa tatatttcaa taatacgcac
     7681 aatacaggcc gtgtcgctat gagtctcttt aaatgatctt actttgtaac tatctaacac
     7741 cgacacatgt tcgttcttaa ttgatgccaa tttcttctta aaaacattgt caaccatata
     7801 tttgccacct caatttagga gtttaatttt ctattgagaa tattcttctc tatccattca
     7861 ttaacttcat gctccaccca tgcaacagaa cgagaaccga tagaaacttg gttcggaaat
     7921 tcatcattct ttatctttag ataaattgtt gacttgggta agccagtcaa attaatcact
     7981 tctgatattc tcagaagtct atatcttttt tggggtgcgt tttcccgagg caataagctc
     8041 atggctatgt ccttcacatt agatatttat actaagactt aattagtctc tattgggtgt
     8101 atatatactt gcacagaaga attaatacgt aaagactggc actttcaaac tcattcaaag
     8161 aatttgaata ctaaataatg gtgaataata gttaataatg gtgagtatta ctgagtgaca
     8221 acctttgcca atgcttgtta atctctgata ataatgaaat ttgacgaata atatatgtaa
     8281 caatttgtaa actaaagact gcattaggtt tgtt
//
LOCUS       DAPOXO010000148         8050 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPOXO010000148 DAPOXO010000000
VERSION     DAPOXO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8050
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.148"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..294)
                     /locus_tag="ROH59_004739"
     CDS             complement(<1..294)
                     /locus_tag="ROH59_004739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX4807128.1"
                     /translation="MFRPFLNSLMLGSLFFPFIAIAGSTAQGGVIHFYGQIVEPACDV
                     STQSSPVEMNCPQNGSVPRKTYSSKALMSGNVKNVQIASVKVQYLDKQKKLAVM"
     gene            complement(415..747)
                     /gene="csgC"
                     /locus_tag="ROH59_004740"
     CDS             complement(415..747)
                     /gene="csgC"
                     /locus_tag="ROH59_004740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HDX4807129.1"
                     /translation="MNALLLLAALSSQITFNTTQQGDMYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            complement(807..1265)
                     /gene="csgA"
                     /locus_tag="ROH59_004741"
     CDS             complement(807..1265)
                     /gene="csgA"
                     /locus_tag="ROH59_004741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HDX4807130.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNS
                     ELNIYQYGGGNSALALQADARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSA
                     TLDQWNGKDSTMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            complement(1306..1761)
                     /gene="csgB"
                     /locus_tag="ROH59_004742"
     CDS             complement(1306..1761)
                     /gene="csgB"
                     /locus_tag="ROH59_004742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HDX4807131.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGSANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
     gene            2514..3164
                     /gene="csgD"
                     /locus_tag="ROH59_004743"
     CDS             2514..3164
                     /gene="csgD"
                     /locus_tag="ROH59_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HDX4807132.1"
                     /translation="MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWP
                     HINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
     gene            3169..3558
                     /gene="csgE"
                     /locus_tag="ROH59_004744"
     CDS             3169..3558
                     /gene="csgE"
                     /locus_tag="ROH59_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HDX4807133.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            3583..3999
                     /gene="csgF"
                     /locus_tag="ROH59_004745"
     CDS             3583..3999
                     /gene="csgF"
                     /locus_tag="ROH59_004745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HDX4807134.1"
                     /translation="MRVKHAVVLLMLISPLSWAGSMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            4026..4859
                     /gene="csgG"
                     /locus_tag="ROH59_004746"
     CDS             4026..4859
                     /gene="csgG"
                     /locus_tag="ROH59_004746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HDX4807135.1"
                     /translation="MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGKFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     VGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKTERQNDILVKYRHMSVPPE
                     S"
     gene            complement(4924..5415)
                     /locus_tag="ROH59_004747"
     CDS             complement(4924..5415)
                     /locus_tag="ROH59_004747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDX4807136.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLVFGYAMKNSGLWLAARSTKTAHREQQIK
                     NKA"
     gene            complement(5517..6071)
                     /gene="ycdY"
                     /locus_tag="ROH59_004748"
     CDS             complement(5517..6071)
                     /gene="ycdY"
                     /locus_tag="ROH59_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone YcdY"
                     /protein_id="HDX4807137.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMTQVSADYNALFIGDECAVPPYRSAWVEGATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDSEE"
     gene            complement(6095..6832)
                     /gene="ycdX"
                     /locus_tag="ROH59_004749"
     CDS             complement(6095..6832)
                     /gene="ycdX"
                     /locus_tag="ROH59_004749"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
                     /protein_id="HDX4807138.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKYQVALEINNS
                     SFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPER
                     ILNVSPRRLLNFLESRGMAPIAEFADL"
     gene            complement(6887..7825)
                     /gene="ghrA"
                     /locus_tag="ROH59_004750"
     CDS             complement(6887..7825)
                     /gene="ghrA"
                     /locus_tag="ROH59_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HDX4807139.1"
                     /translation="MDIIFYHPTFDTQWWIEALHKAIPQARVRAWKSGDNESADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRLQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVDYISRTIAQLEKGERVCGQVDRARGY"
BASE COUNT         2208 a         1917 c         1765 g         2160 t
ORIGIN      
        1 cattacagcc agctttttct gtttatcaag atactgcact tttactgagg ctatttgcac
       61 gtttttaaca ttgccgctca ttaaggcttt gctggaatag gttttacgcg gaacagaacc
      121 attctgtggg cagttcattt ctacgggtga tgactgggtg ctgacgtcac atgccggttc
      181 cacaatttgg ccataaaaat ggatcacgcc cccttgcgcg gtgcttcctg caatggcaat
      241 aaaaggaaaa aacaaactgc cgagcataag agagtttaaa aaaggtctga acatttattc
      301 tatttcctca atgattagtc atccttgagg gttgtgttat ccatactttc aggttggctg
      361 attcgcagca gaccattctc tccaggttca tcttatgctc gatatttcaa caaattaaga
      421 cttttctgaa gagggcggcc attgttgtga taaatgaagt gactgtccat cagaaacagt
      481 aacaactatt ttcacccgat cgtccgggga aatatttaaa ctcaacttcg tcaaagcaat
      541 gggttgatta gcaggcaatg agagggtctt ttcttgcttc gtctgacttt gccctgaact
      601 gccttcgcgc agggacaata tttgtactct gcacagacaa gattgagtaa gagtgacttc
      661 aggaataatg gtgtacatat ccccttgctg ggtcgtatta aaggttatct gactggaaag
      721 tgccgcaagg agtaataacg cattcatatt cttctcccga aaaaaaaaca gggcttacgc
      781 cctgtttctt tcatacagat gatgtattag tactgatgag cggtcgcgtt gttaccaaag
      841 ccaacctgag tgacgttaac gctggagtta gatgcagtct ggtcaacagc agcaccgtta
      901 ccgccaccga actgtttaac agtcatagta gaatctttac cattccactg atcaagagta
      961 gcgctgttgc cgaaaccacg ctgagtcaga tcgattgagc tgtcatcaga accttggcca
     1021 acatctgcac cattaccgcc gccgtgctgg gtaatggtca gatcagagtt gcgggcgtca
     1081 gcttgcagag caagagcaga gttaccgcca ccgtactggt aaatattcag ctctgaattc
     1141 gggccgctgt tattaccgcc accaccgtgg ttgccgccac cgccgccgta ctgaggaaca
     1201 acacctgcca gagcgctacc ggagaatacg attgctgcaa ttgctgctac ttttaaaagt
     1261 ttcatgtaaa acccccatcg gattgattta aaagtcgaat ggaaattaac gttgtgtcac
     1321 gcgaatagcc atttgcgact gtctctgcac tacaattgcc gttttttgag taccatactg
     1381 tgtaatattt gctttattac cagaaccttt ctggataatc atcgcagtat taccataagc
     1441 accttgcgaa atactggcat cgttggcact gcccgcctga tcaatatatg caaggttata
     1501 atctcctgtc tggtcaatct ttgcccggtt gctactacct tcttgcgcaa caaccgccaa
     1561 aagttttgag cctccctgcc gtaactgagc actattatta gtcccagctt gaccaattat
     1621 ggctgcctga ttaaatgaag acttactcaa ttcatttacc gcaaagttat attctgaatt
     1681 agctaaatca taacctgctg cggctgcaat cccaggcgca cccagtattg ttaacatcat
     1741 aaataacaat ttgtttttca tgttgtcacc ctggacctgg tcgtacattt aagaaattaa
     1801 atcatttcaa cttggttgtt aacgcaaccc gtattttgtt aacgctgcgt tacgatggaa
     1861 agtatgtctg cggaaatatt tttaataact cacccgcgcg ttgtattttt ctttttttgt
     1921 tcataccaaa gtattaaaac ccacgtaaat acgctgttat ctacgcaaaa aatattttgt
     1981 tttcttttaa atctccgttt tccgctatca aaaatcacca gacagtcatt cttcttgccc
     2041 gtcgctgatt gctgcgatat gtcttgcgca caagccgtga caaacctcgt ctttttgcag
     2101 taaaaaattg tccacggtgg tatggagaaa aaacaagaac gttttacatg acgaaaggac
     2161 tacagcgaaa tattttttat atgcattatt agtaagttag caccatttgt atgatttttt
     2221 aaaattgtgc aataaaaacc aaatgtacaa cttttctatc atttctaaac ttaataaaac
     2281 cttaagatta acattttaat ataacgagtt acatttagtt acatgtttaa cacttgattt
     2341 aagatttgta atggctagat tgaaatcaga tgtaatccat tagttttata ttttacccat
     2401 ttagggctga tttattacta cacacagcag tgcaacatct gtcagtactt ctggtgcttc
     2461 tattttagag gcagctgtca ggtgtgcgaa caataaaaaa gcggggtttc atcatgttta
     2521 atgaagtcca tagtattcat ggtcatacat tattgttgat cactaaacct tctttgcaag
     2581 cgacagctct cttgcagcac cttaaacaat cgctggcgat tacaggaaaa ttacataata
     2641 ttcaacgttc tctggacgat atatcttcag gctctattat tcttctggat atgatggaag
     2701 cggataaaaa gcttatccat tattggcagg atactttgag caggaaaaac aacaatatca
     2761 aaatattgtt gctaaatacg cctgaagatt acccgtaccg cgacattgaa aactggcctc
     2821 atatcaacgg cgttttttat gccatggagg atcaagaacg tgttgtcaat gggttgcaag
     2881 gcgtcctgcg cggcgaatgc tactttacgc aaaagcttgc cagttacctg attacgcatt
     2941 caggtaacta tcgttataac agcacggaat cagccctcct tactcatcgg gaaaaagaga
     3001 tcctgaataa gctgcgtatc ggcgcgtcta ataacgagat cgctcgttcg ttgttcatca
     3061 gcgaaaatac ggttaaaacg catctttata atcttttcaa gaagatagcc gtaaaaaacc
     3121 ggacacaagc ggtttcctgg gcaaacgata acctcaggcg ataaagccat gaaacgttat
     3181 ttacgctgga ttgtggcggc agaatttctg ttcgccgcag ggaatcttca tgccgttgag
     3241 gtagaagtcc cgggattgtt aactgaccat actgtttcat ctattggcca tgatttttac
     3301 cgagccttta gtgataaatg ggaaagtgac tatacgggta acttaacgat taatgaaagg
     3361 cccagtgcac gatggggaag ttggatcact ataacggtca atcaggacgt tattttccag
     3421 acttttttat ttccgttgaa aagagacttc gagaaaactg tcgtctttgc actgattcaa
     3481 actgaagaag cactaaatcg tcgccagata aaccaggcgt tattaagtac gggcgatttg
     3541 gcgcatgatg aattttaaat aataaattgt tcggaggctg caatgcgtgt caaacatgca
     3601 gtagttctac tcatgcttat ttcgccatta agttgggctg gatccatgac tttccagttc
     3661 cgtaatccaa actttggtgg taacccaaat aatggcgctt ttttgttaaa tagcgctcag
     3721 gcacaaaact cttataaaga tccgagctat aacgatgact ttggtattga aacgccatca
     3781 gcgttagata actttactca ggccatccag tcacaaattt tgggtgggct actgtcgaat
     3841 attaataccg gtaaaccggg ccgcatggtg accaacgatt atattgttga tattgctaac
     3901 cgcgatggtc aattgcagtt gaacgtgaca gatcgtaaaa ccggacaaac ctcgaccatc
     3961 caggtttcgg gtttacaaaa taactcaacc gatttttaag ccccagcttc ataaggaaaa
     4021 taatcatgca gcgcttattt cttttggttg ccgtcatgtt actgagcgga tgcttaaccg
     4081 ccccgcctaa agaagccgcc agaccgacat taatgcctcg tgctcagagc tacaaagatt
     4141 tgacccatct gccagcgccg acgggtaaga tctttgtttc ggtatacaac attcaggacg
     4201 aaaccggaaa atttaaaccc tacccggcaa gtaacttctc cactgctgtt ccgcaaagcg
     4261 ccacggcaat gctggtcacg gcactgaaag attctcgctg gtttataccg ctggagcgcc
     4321 agggcttaca aaatctgctt aacgagcgca agattattcg tgcggcacaa gaaaacggca
     4381 cagttgccat taataaccga atcccgctgc aatctttaac ggcggcaaat atcatggttg
     4441 aaggttcgat tatcggttat gaaagcaacg ttaaatcggg cggtgttggg gcaagatatt
     4501 ttgggatcgg tgcagacacg caataccagc ttgatcagat tgccgtgaac ctgcgtgtcg
     4561 tcaatgtgag taccggtgag atcctctcct cggtgaacac cagtaagacg atactttcct
     4621 atgaagttca ggcgggggtc ttccgcttta ttgactacca gcgcttgctg gaaggggaag
     4681 taggttacac ctcgaacgaa cccgttatgc tgtgcctgat gtcggctatc gaaacaggcg
     4741 tcattttcct gattaatgat ggtatcgacc gcggcctttg ggatttgcaa aataaaacag
     4801 aacggcagaa tgacattctg gtgaaatacc gccatatgtc ggttccaccg gaatcctgat
     4861 agataaaaac gccggaatta ataatccggc attttactgt ttaagcgaaa gcgtgagtgc
     4921 ccctcacgct ttatttttga tttgctgctc acggtgagcg gtcttcgtac tacgcgccgc
     4981 cagccacagg ccgctgtttt tcattgcgta accaaatacc agtccaagcg ccagcgaagg
     5041 taacaccagt ttccagtccc cctgcccggc aaacgtcgcg catgcgccta taaacgtccc
     5101 cggaacaaat gaaagcagca gctgtttggc ctgaatacac atcagaaacg cgacaatacc
     5161 ggttattaca taaccgagaa tttccagatg tggtgccagt gcactaccgt aaataatgac
     5221 catcgcccac accacgccac taagcagggt tgcagcggag atcgccagcc ctttcagccc
     5281 accttgcggg caggcaaagt aggccgtaca gcccaggaag cccgcccagc ttagtaagcc
     5341 cagggaaaca gccacccatc cccagatacc ggagagaatg cctgttgtga ttgcaataga
     5401 gagaagtatg ttcatgccgc gcatgatagc agaaaacgcg gccatgaatg agatcgagca
     5461 cacattttat gcaacaacaa attatcagtt gcagttatga gtgatgcaga tcacatttac
     5521 tcttcagaat cttcttccag ctcgtcccac attgcactaa tagcatcgcg ggttagcggt
     5581 gccatggtgc gccagaaagg cgtagttgca tgggcctcca ctttgccaag gaacgcacca
     5641 caccagggta acagatactc actgaacagt gtttccagtg cttcgctctc atcttccgtt
     5701 gactgatctt ccagccagga agccgcaagc agcaatgtgc cgatgtgatc ggctggcgta
     5761 tccgctagtg gcatccctcg ttcggaaaga aaagcgcgca cttccgcttc cgttgcgccc
     5821 tcaacccatg cgctacgata tggcggcaca gcacattcat cgccgataaa caacgcattg
     5881 taatcggcag agacttgcgt catatcacag cttttctgta aacgcgtcag taactcatcc
     5941 tgctccagtg gccagttcgc agccagtttc ccctcacgaa tcagggtaaa caacggcacc
     6001 agtaaaggat cttgcggttg gcggtaatag agcgaaccca gcacacgaca gaggatagaa
     6061 aactcgttca ttaatatatt tccattacta gtaattaaag gtctgcaaat tccgcaatcg
     6121 gtgccatacc gcgagattca aggaagttca gtaagcggcg cggagaaaca ttcaaaatgc
     6181 gttctggcgg aaaatctacc gcgtcgagga ttttaagaca ctcttcaaat tcccccatgg
     6241 taaatgcagt gtgagaatcc gagcctaatg ccacccaacc tccagcgtca cgtaccgctg
     6301 cagctaccgc acgacagttg tcttcactgc ccttacgtga gtgtaaaaat gaggaattat
     6361 tgatttccag cgccacctga tatttcgcgg ctgcttcagc aacggcttta acatctatct
     6421 catatttcgg atttccggga tggcttatta tatgcacatt gccgctggcg atagtggcga
     6481 tcatcgcttg tgtattggtt gctttgtcat gtggcgcaaa aaccggctca tgaaaaccgg
     6541 caataatcag atccagcgaa tcaaacattt tgccgctgca atcaatttca ccatcaacat
     6601 ttttaatgtt agcttcgatg ccgcgcagga tccctacccc atcaaccact cgcggccaga
     6661 tacgcatgtt aatgaagtgc cagtgatgcg gcgcatcttc catatccggg ccatgatcgg
     6721 tgatcgcaaa aagtttaatg cccttttgtt tggcctgggc aatgtaatca ctcaatgtgc
     6781 tatatgcatg cgtgctggca acggtatgca tatgaaggtc gacgggatac ataactctct
     6841 cctgtattca attcccgcca aggatagcag gaaacctgat gctttattag tagccgcgtg
     6901 cgcggtcgac ttgcccgcag accctctccc ctttttcgag ctgggcaatg gtgcgcgaaa
     6961 tgtaatccac agcttcagcg ggacgggtaa tcgcggcgac atgtggtgtt atcgtcacgc
     7021 gtggatgttg ccagagcgga ctttccggcg gtaagggttc acgattaaaa acatccagca
     7081 ttgcgccttt aactttgccg ctatccagcg ccgcgagcag gtcatcttcc acgacatgaa
     7141 caccacgcgc caggttgagg agatacgcgc catccggtaa tttttcgagt aattgttgat
     7201 taataatgcc gacggtttca ggggtattcg gtaacaaatt aatcaatacc cggcattggc
     7261 tcagaaatgc agaaagttct tcccgtccgg caaagctttg cacgccaggc cacgatttac
     7321 gggttcgact ccagcaacgc agcgggaagc gccaggtttg cagactctgt gcaactttac
     7381 tgcccagtac gcctgcgccc aaaatgccga tggtaaaatc ttcccgatga tattcaggca
     7441 gcggttgcca atgcgaacta ttttgctgga ggcggtaatc gtcaaaacgt cgaaaccaat
     7501 gcagcacctg actgacagca tattcctgca tttgctcgcc cataccggta tcttccaggc
     7561 gaaaaagtgg aacagaaggc ttcagcattt cagggtgagc ctgtagcttg ctcaaaatag
     7621 aatcaacacc tgccccaagt gcaaacaccg ctttaagatc gcgccctgcc agcatttcaa
     7681 caggaggatg ccagactaaa gcataatcgg ctgattcatt gtctccgctt ttccatgctc
     7741 tgactcttgc ctgaggaata gctttgtgca gtgcctcaat ccaccattgg gtatcgaacg
     7801 ttgggtgata aaagatgata tccatactga ctcccgaaaa gcgttgcgcg aaatttattc
     7861 gcacttatcg ttatgatcta caaaggccac cagcataaca aatccgtggt cggtgacaaa
     7921 aaaagcaaat ttcgcttatt aaaactacat attgattgaa gtttgaataa tcgagcgatt
     7981 ttttaaaaaa gtttgttgac ctcaggtcat gatttcccta aattagcgcc cgttccagca
     8041 agacaggaac
//
LOCUS       DAPOXO010000149         8034 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.149, whole genome shotgun sequence.
ACCESSION   DAPOXO010000149 DAPOXO010000000
VERSION     DAPOXO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8034
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.149"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            30..632
                     /locus_tag="ROH59_004751"
     CDS             30..632
                     /locus_tag="ROH59_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HDX4807140.1"
                     /translation="MNINYPAEYEIGDIVFTCIGAALFGQISAASNCWNNHVGIIIGH
                     NGEDFLVAESRVPLSTITTLSRFIKRSANQRYAIKRLDAGLTEQQKQRIVEQVPSRLR
                     KLYHTGFKYESSRQFCSKFVFDTYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFL
                     GSIPWERKTVTPASLWHHPGLVLIHAVGVETPQPELTEAV"
     gene            complement(634..1155)
                     /gene="ruvC"
                     /locus_tag="ROH59_004752"
     CDS             complement(634..1155)
                     /gene="ruvC"
                     /locus_tag="ROH59_004752"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDX4807141.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(1190..1930)
                     /locus_tag="ROH59_004753"
     CDS             complement(1190..1930)
                     /locus_tag="ROH59_004753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX4807142.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(1959..2411)
                     /gene="nudB"
                     /locus_tag="ROH59_004754"
     CDS             complement(1959..2411)
                     /gene="nudB"
                     /locus_tag="ROH59_004754"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HDX4807143.1"
                     /translation="MTDMAYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(2404..4176)
                     /gene="aspS"
                     /locus_tag="ROH59_004755"
     CDS             complement(2404..4176)
                     /gene="aspS"
                     /locus_tag="ROH59_004755"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDX4807144.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILERTGAQDGDMI
                     FFGADNKKIVADAMGSLRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            4486..5052
                     /locus_tag="ROH59_004756"
     CDS             4486..5052
                     /locus_tag="ROH59_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDX4807145.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPVALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILHAL"
     gene            5049..5867
                     /locus_tag="ROH59_004757"
     CDS             5049..5867
                     /locus_tag="ROH59_004757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDX4807146.1"
                     /translation="MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKP
                     EVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQL
                     PATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVIL
                     DSRPVHAARPHSEAIRYAQRKKPKVPVHAVLTAKNPLIRFIGSDDMTQNRELFQVWLQ
                     KLAQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            5920..6315
                     /locus_tag="ROH59_004758"
     CDS             5920..6315
                     /locus_tag="ROH59_004758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HDX4807147.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            6356..7099
                     /gene="cmoA"
                     /locus_tag="ROH59_004759"
     CDS             6356..7099
                     /gene="cmoA"
                     /locus_tag="ROH59_004759"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HDX4807148.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HKAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            7096..>8034
                     /gene="cmoB"
                     /locus_tag="ROH59_004760"
     CDS             7096..>8034
                     /gene="cmoB"
                     /locus_tag="ROH59_004760"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HDX4807149.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPTQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVS
                     VTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAP"
BASE COUNT         1844 a         2096 c         2024 g         2070 t
ORIGIN      
        1 attcatatct atttcaatgg aatgacaacg tgaatattaa ttatcctgcg gaatatgaaa
       61 ttggtgatat cgtctttaca tgtataggtg ctgccttatt tggtcaaata tcagctgcat
      121 caaattgctg gaataatcac gtcgggatca ttatcggtca taacggtgaa gactttctgg
      181 ttgcagaaag ccgtgttccc ctctcaacca tcactacgct atcccgtttt attaaacgct
      241 ctgctaatca acgctatgct ataaagcgat tagacgccgg actaacagaa caacaaaaac
      301 aacgaattgt tgaacaggtt ccttcccggc tacgcaaact ttaccacacc ggttttaaat
      361 acgaatcttc gcgacagttc tgttcaaaat ttgtttttga tacttataaa gaggcgctat
      421 gtattccggt gggtgaaata gagacgtttg gagaattatt aaatagcaat ccgaatgcaa
      481 aactcacttt ctggaaattc tggttcttag gttctattcc gtgggagcgt aaaaccgtca
      541 cgccagccag tttgtggcat catccgggtt tggtgttgat tcacgcggtg ggagttgaaa
      601 cgcctcagcc tgaactgacc gaggcggtat aacttaacgc agtcgccctc tcgccaggtt
      661 cagtcgcgat tcactcattt gcatcgcatt ctgactaacg tggcagtggg tgatggcaat
      721 cgccagcgca tcggcggcat ccgcctgtgg attagcgggc agtttcagca aggtgcggac
      781 catatgctgc acctggcttt tttcggcact accaatacct accactgttt gctttacctg
      841 acgtgccgca tattcaaata ccggcaattc ctgattcacc gccgccacaa tcgccacgcc
      901 gcgcgcctgc cccagtttca gggctgagtc agcgttcttc gccataaaga cttgttcaat
      961 ggcgaaataa tcaggctgga attgggtgat gatttccgtc acgcccgcat agatgagctt
     1021 cagacgagac ggtaaatcat ccactttggt gcgtatgcat ccgctaccca ggtaggacag
     1081 ttgcctgcct acctggcgga tgacgccata gccggtcacg cgcgaacccg ggtcaatacc
     1141 gagaataata gccatcacgc gtctccgttt tgctgtttag caggcctcat cagagagtcg
     1201 ctgcaacctc atcagagatt tcaccgttat ggtaaacttc ctgcacgtcg tcgcaatctt
     1261 ccagcatatc gatcagacgc atcagtttcg gtgcggtttc tgcatccata tcagctttgg
     1321 tggacgggat catggaaact tccgcgctgt ctgctttcag acctgccgct tccagagcgt
     1381 cgcgtacttt gcccatttct tcccatgcag tgtagacatc aatcgcgccg tcatcatagg
     1441 tcacaacgtc ttcagcaccg gcttccaggg ctgcttccat gatggtgtct tcatcgcctt
     1501 tctcgaagga gatcacgcct tttttgctga acagataagc tacggaacca tcagtaccga
     1561 ggttaccgcc acatttgctg aatgcatgac gcacttcagc aacggtacgg ttgcggttgt
     1621 cagacagaca ttcaatcatg attgccgtgc cgccaggacc gtaaccttcg tagatgatgg
     1681 tttccatgtt tgcatcatca tcaccgccca cacctcgtgc aattgcgcgg ttcagagtgt
     1741 cacgggtcat gttgttagac agtgctttat caattgctgc acgcagacgc ggattagcgt
     1801 ccggatcacc accgcccagc ttagccgcgg ttaccagctc acgaatgatt ttagtgaaga
     1861 ttttaccgcg cttagcatcc tgcgcagctt tacgatgtct ggtgttggcc catttactat
     1921 gacctgccat aaaaatatct ccagatagcc ctgcctgttc aggcagcgtt aattacaaac
     1981 tgttcaatcg cctgccggtt gctccaggac ttagtgagcg ccgccgcagc aggcgcatca
     2041 agccacttgt aagccagatg ttcagtgaaa acgatctggc gctcgtgcgg gagcgcaaga
     2101 cagaaccatg attccgtatt acgcgtcacg cccggcgcat agcgatgacg taaatgtgaa
     2161 aaaatttcaa actctaccgt gcgctgacag tcaattaagg tcagttgttc agcgacaaca
     2221 tcaatggtga cctcttcctt tacttcgcgc atggcagctt gcggcgcggt ttcaccctct
     2281 tccacgctgc cggttaccga ctgccagaaa tcgggatcgt cacgccgctg caacatcagc
     2341 acccgtttcg tatcttgtgc gtagatgacc actaagatcg aaacgggacg cttataagcc
     2401 atatcagtta ttctcagcct tcttcacaac ctgaatgctc agctcagcca gtgcagtcgg
     2461 gttagcaaag ctcggtgctt cagtcatcag acacgccgcc gccgtggttt tcgggaaggc
     2521 gataacgtca cggatattgt cggtgccggt cagcagcatg gtcagacggt caagaccgaa
     2581 tgccagacct gcgtgcggcg gagtaccgta tttcagggcg tcgagcagga agccgaattt
     2641 ctcgcgctgt tcctcttcgt tgatacccag aataccaaac accgtctgct gcatatcacc
     2701 attatggata cgcacagaac caccgcccac ttcgtaacca ttgatgacca tatcgtaagc
     2761 gttagccacc gcattttccg gtgcagcttt cagttctgct gccgtcatgt ctttcggtga
     2821 ggtgaacgga tggtgcattg ctgtcaggcc gccttcaccg tcgtcttcaa acatcgggaa
     2881 gtcgataacc cacagcggtg cccatttgct ttcgtcggtc agaccaaggt ctttacccac
     2941 tttcaggcgc agtgagccca tcgcgtcggc aacaattttc ttgttgtcgg caccgaagaa
     3001 aatcatatcg ccatcttgcg cgccagtacg ctccaggatg gcttcgatga tttctgcatt
     3061 aaggaacttc gctaccgggc tgttgatacc ttccagacct ttcgcgcgtt cgttaacttt
     3121 gatgtaagcc agacctttcg cgccgtagat tttaacgaag ttaccgtatt cgtcgatctg
     3181 cttacgggtc aacgatgcgc cgcccggaac acgcagagcg gcaacacggc ctttcggatc
     3241 gttcgccgga cctgcaaata ctgcaaactc aacagatttc agcagatcgg caacgtcggt
     3301 cagttccatc gggttacgta gatctggttt atcagaacca taacggcgtt ctgcttctgc
     3361 aaaggtcatt accgggaaat cgcccagatc cacgcccttc acttccagcc acagatgacg
     3421 caccagcgct tccatcactt cacgcacttg cggcgcggtc atgaaagaag tttccacatc
     3481 gatctgagta aattcaggct gacggtcagc acgcaggtct tcgtcacgga agcatttaac
     3541 gatctgatag tagcggtcaa agccggacat catcagcagc tgtttgaaca actgtgggga
     3601 ttgcggcagt gcgtagaatt tacctttgtg cacacgagaa ggcaccaggt agtcacgcgc
     3661 gccttccggc gtggctttgg tcagcatcgg agtttcgatg tcgaggaagc cgtggtcatc
     3721 cataaaacgg cgcaccaggc tggtgatttt agcgcgggtt ttcaggcgct gagccatttc
     3781 cgggcgacgc aggtcgaggt agcggtattt cagacgcgct tcttcggtgt tgacgtggtt
     3841 agagtcaagc ggcagaacat ctgcacggtt gatgatagtc agcgaggacg ccagtacttc
     3901 gatttcgcca gtcgccatat cgcggttaat atttttttcg tcacgcgcac gtacggtgcc
     3961 cgtgacctga atgcagaact cattacgcag ttcagaggcc agctttaacg cgtccgcacg
     4021 atccggatcg aaaaatacct gcacgatacc ttcgcggtcg cgcatatcga tgaagatcag
     4081 gctaccaaga tcacgacgac ggttgaccca accacacaga gtcacctgct gccccacgtg
     4141 ggacaaacgg agctgtccac aatattctgt acgcatgaga tatcccttaa cttagctgcc
     4201 ggcggatgcc ccctgctgcg caggtgacca agtcgcagcg ttagctgtat gtcacaactg
     4261 aatgaaaaaa ggcggctatt atactggaaa ttctgccgca ccgtaagagc ctggcccgcg
     4321 ctggaacgcc tcgttaccac tttatatcgg gcctgaaatc agactctacg ccagtttgct
     4381 ataaaggtgt tgcccgaact cataaaaatt aacaaaattt gtcgttccgc catcggctca
     4441 tcgtattaag gtgagaggca cgattttgtt ttatcaggag tcatcatgct tgaacttaat
     4501 gctaaaacca ccgcgctggt ggtgattgat ttacaagaag gcatcttgcc ttttgccggt
     4561 ggtccacata ctgccgatga ggtggttaat cgcgccggga agctggcggc gaaatttcgc
     4621 gcgagcggtc agcccgtgtt tctggtgcgt gttggctggt ctgccgatta tgctgaagca
     4681 ttaaaacagc cggttgatgc cccttccccc gctaaagtgt tgcccgaaaa ttggtggcaa
     4741 catcctgtag cattaggtgc aaccgacagc gatatcgaaa tcatcaaacg tcaatggggt
     4801 gcgttttacg gtacggatct ggaattgcag ttgcgccgcc ggggtatcga tacaatagtg
     4861 ttatgtggga tctcgaccaa tatcggtgtt gaatccaccg cccgcaatgc ctgggaactc
     4921 ggttttaatc tggtgattgc cgaagatgcc tgtagcgccg ctagcgccga gcagcacaat
     4981 aacagcatta atcatatcta cccgcgcatc gcccgtgtgc gtagcgttga agagatcctc
     5041 cacgcgttat gatttacatc ggtttgccac aatggtcgca tcctaaatgg gtgcggttgg
     5101 ggatcaccag ccttgaagag tatgcccgcc actttaactg tgtggagggt aacaccacgc
     5161 tttatgccct gccgaaaccc gaggttgtcc tgcgctggcg tgagcagacc acagatgact
     5221 tccgcttctg ttttaagttt ccggcgacta tttcgcatca ggcagcatta cggcattgcg
     5281 atgatttagt gactgaattt ttgacccgca tgtcaccgtt ggctccgcgc attggacaat
     5341 actggctgca actgcctgcc acattcggcc cacgggagct gcctgcgctt tggcattttc
     5401 tcgattctct tcccggcgaa tttaattatg gtgtggaagt ccgccatcca cagtttttcg
     5461 ccaaagggga agaggaacaa acgcttaatc gcggtttaca tcagcgcggc gttaatcggg
     5521 tgattttaga cagccgcccg gttcatgcag cacgtccaca cagtgaagct attcgctacg
     5581 ctcaacgaaa aaaacctaaa gttccggtac atgctgtact gacggcgaaa aatccactga
     5641 tccgttttat cggtagtgat gatatgacgc aaaaccggga attatttcag gtctggttac
     5701 aaaaattagc gcagtggcat cagaccacta cgccttatct ttttttacat acgccagata
     5761 ttgcccaggc cccggaactg gtacataccc tgtgggaaga cttacgtaaa acgcttccag
     5821 agatcggagc agttccggct attccacagc aatcttctct tttctgaatt tgccacctat
     5881 catagacagg tgccatcggc cattttaaag ggagtttgta tggtaagcgc gctgtatgcc
     5941 gttttaagtg cgttgttatt aatgaagttc tcttttgatg tcgttcgcct gcgaatgcag
     6001 taccgcgttg cctatggcga cggcggtttt agcgaactgc aaagcgctat tcgcattcat
     6061 ggtaacgcgg tggaatatat tcccatcgcg attgtgttga tgctgtttat ggaaatgaat
     6121 ggcgcagaaa cctggatggt gcatatttgc ggcatcgttt tgcttgctgg tcgtctgatg
     6181 cattattacg gttttcatca ccgtctgttc cgctggcgac gttctggcat gagcgccacc
     6241 tggtgtgcgc tgttgctgat ggtgctggcg aatctttggt atatgccctg ggagttggtt
     6301 ttctccctgc gttagcgcac aatacgccac tttctttttc ccggattttt acgttatgtc
     6361 tcaccgcgac acgctatttt ctgcccctat cgccagactg ggcgactgga cctttgatga
     6421 acgggtagct gaagtcttcc cggatatgat ccagcgttcc gttcccggct attccaatat
     6481 tatttccatg attggtatgt tagccgagcg cttcgttcaa cctggtacgc aggtttacga
     6541 tctgggttgt tctctgggcg cggcgacact ctcggtgcgt cgcaacattc atcatgataa
     6601 ttgcaaaatt attgccatcg ataactcccc ggcgatgatt gaacgctgcc gtcgtcatat
     6661 tgacgcctat aaagctccta cgccagtaga cgttattgaa ggtgatattc gcgatatcgc
     6721 cattgaaaac gcatcgatgg tggtgctgaa ttttaccctg caattcctgg aaccttccga
     6781 gcgccaggcg ttactggata aaatttatca aggactgaac ccgggcggcg cgctggtgct
     6841 ttcggaaaaa ttcagtttcg aagatgccaa agttggtgaa ctgctgttca acatgcacca
     6901 cgactttaaa cgtgccaacg gttacagcga actggagatc agccagaaac gcagcatgct
     6961 ggaaaacgtg atgctgaccg attccgtgga aacccataaa gcacgcctgc ataaagccgg
     7021 ttttgagcat agcgagctgt ggttccagtg ctttaacttt ggttcactgg tggcattaaa
     7081 agcagaggac gctgcatgat cgactttggt aacttttatt ctctgattgc caaaaatcat
     7141 ctttcacact ggctcgaaac gctgcccacg cagattgcta actggcagcg cgagcagcag
     7201 cacgggctgt ttaagcagtg gtccaacgcg gtggaatttc tgcctgaaat taaaccgtat
     7261 cgtctggatt tattgcatag cgtaaccgcc gaaagcgaag agccactgag cgccgggcaa
     7321 attaagcgca ttgaaacgct gatgcgcaac ctgatgccgt ggcgcaaagg gccgttctca
     7381 ctgtatggcg tcaacatcga taccgaatgg cgttccgact ggaaatggga tcgcgttctg
     7441 ccccatcttt ctgatttaac cgggcgcacc attcttgatg tcggctgcgg cagcggttat
     7501 cacatgtggc gcatgattgg cgctggcgcg cacctcgcgg tggggatcga ccctacacaa
     7561 ctgtttctgt gccagtttga agcggtgcgt aaactactgg gtaacgatca gcgcgcacat
     7621 ttgttaccgt taggtattga acaacttccg gcactgaaag cctttgatac cgtcttttcg
     7681 atgggcgtgc tttatcatcg tcgttcaccg ctggagcatc tctggcagtt aaaagaccaa
     7741 ctggtgaatg aaggcgaact ggtgctggaa acgctggtta ttgatggcga tgagaacacg
     7801 gtgctggtgc cgggcgatcg ttacgcacaa atgcgtaatg tctatttcat tccttccgcg
     7861 ctggcgctga aaaactggct gaagaagtgt ggttttgttg atattcgcat tgcggatgtg
     7921 agcgttacca ccacagaaga gcagcgacgc accgaatgga tggtcaccga gtctctggcc
     7981 gattttctcg acccgcatga tccgggtaaa acggtggaag gttatcctgc gcct
//
LOCUS       DAPOXO010000150         7951 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.150, whole genome shotgun sequence.
ACCESSION   DAPOXO010000150 DAPOXO010000000
VERSION     DAPOXO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7951
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.150"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(7..420)
                     /locus_tag="ROH59_004761"
     CDS             complement(7..420)
                     /locus_tag="ROH59_004761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4807150.1"
                     /translation="MNTKTKNMAFASRLQRILKDLGWSQSELARHIGVTAQSVQAWCN
                     GVTPRKDKLDKLAKVTGYPVHFFFMNEGEYLDESTLHPGNYNQELTPQEQALLQLFRG
                     LPESEKNKLINELKEKREHFDLLLKELLEAKNQTK"
     gene            519..749
                     /locus_tag="ROH59_004762"
     CDS             519..749
                     /locus_tag="ROH59_004762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX4807151.1"
                     /translation="MDKQLQDKILSVMSQSELGRRLGKKPQTVSLWFKGRVPGEEVLR
                     TSEALEWRVTPHDLRPDLYPNPDDSLPKTEAA"
     gene            808..1284
                     /locus_tag="ROH59_004763"
     CDS             808..1284
                     /locus_tag="ROH59_004763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000431205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807152.1"
                     /translation="MENQEELQKEILTWAARAGQELVTIEICRAWFSQGRNDELRLHE
                     FEDADGNVDWRAINNNRQKIFRWLRGETTAARRKTQVLASVMKAVLPAERRARLESPG
                     DPVLLATLAAKEGVEAINAVHLHFAPELTIQEIDEAIAALVATRGAVIRTAQDHHA"
     gene            1324..1548
                     /locus_tag="ROH59_004764"
     CDS             1324..1548
                     /locus_tag="ROH59_004764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807153.1"
                     /translation="MLRHIDRITWRNGWHLNGRPAHVAEIRPIFDGRVAAARSVWEKY
                     EEEKAKLREQNLSGAAYEAGCRVLSEALGI"
     gene            1545..2300
                     /locus_tag="ROH59_004765"
     CDS             1545..2300
                     /locus_tag="ROH59_004765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001023813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDX4807154.1"
                     /translation="MNILPLLDRPIAFQRSFIRLEMGVTAALFLSQLTYWTNRTTDDG
                     WVYKTQDEWEEETGLSRYEQEGARKKLRGLGVLLERKQGLPARLYYKIDNDVLCQLLT
                     SAYKDAEKPHTGEGKTTRPVRGKPTNILTENTTEIITDGESADADTQQPADQRINYQV
                     ILDTYHEILPEMPPVKILTDGRKKHLRTFWKKFNFNESRWRAYLEFIGGNCRWMLEDR
                     PNGRGGFWRRKNLDYLITERCYVSVKEERANDK"
     gene            2290..3705
                     /locus_tag="ROH59_004766"
     CDS             2290..3705
                     /locus_tag="ROH59_004766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX4807155.1"
                     /translation="MINNAIALYSVDAEQAVLGCLMLNTDHDRTNAVFALLKPETFYI
                     NAHQVIYREIKGLFQADKPTDLITLTELMESKGLYERVGGFAYLAEMSKAAIPASMVN
                     YAKIVREKAILRYAVEKLNSCLEIMIQPADMTATDRITAVQQVIGQVAEHSRTGHKGG
                     LRPASEVVDDWIDDLERRFNDPAHAAGLTLGIESLDRLMAPKQALRGSLVVIGARPKM
                     GKTAAFNKIAVHFALNHRLPTLVFSLEMTDRSLIERMVAQEAKVNSEIFYLGPNDESE
                     LSLAIAKAGEIAESNMMIDSTAGVTLAHIVAECRKVKRMRGSVGLVAIDYLTLMKTES
                     AERRDIAYGDITTGLKNLAKELDCVVVLLTQLNRKLEERADKRPNPSDSKDTGQIEQD
                     CDVWIGLYRDAVYNENADPNLMEMLLRLNREGPSGTAYALMKNGSVIDISDEEVYRLT
                     NDRSEKNKRYSRSDNSRTNEF"
     gene            3744..4154
                     /locus_tag="ROH59_004767"
     CDS             3744..4154
                     /locus_tag="ROH59_004767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807156.1"
                     /translation="MTTTPGKLEYPSDKGHIDDGKNYLDVILWNMNVGPRARTRAVFV
                     PRPKAGNFSTPAKPARQASVAAAPAVKRKGKTHTGIAIRRNGERQVKLHETATTWCAS
                     PHETYDKITGQRIGAPGRCRLLLSSITPIAKKGA"
     gene            4156..4392
                     /locus_tag="ROH59_004768"
     CDS             4156..4392
                     /locus_tag="ROH59_004768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807157.1"
                     /translation="MAGQSDYLPPGLPHNRAKWPQEYQLKEHYDMRAAALIRQLFEKR
                     IPRGSVIEQIGMTPDTYREFFRERLNYWRGVMEQ"
     gene            4389..4700
                     /locus_tag="ROH59_004769"
     CDS             4389..4700
                     /locus_tag="ROH59_004769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDX4807158.1"
                     /translation="MKYKRWVRAEVVIIKQCAGSMTVERIGQLIGRTGAAVRTKAREL
                     KICMYLRGNYHQSVKYLQEDIELARELHQSGINRQDIAEKLEMPIGAVNQFVYFERRI
                     S"
     gene            4697..4921
                     /locus_tag="ROH59_004770"
     CDS             4697..4921
                     /locus_tag="ROH59_004770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807159.1"
                     /translation="MKELFLAFVPRFINDQIALTDNGEQYEIACSMVDVNPGERYDAM
                     CDLKIFTWLGWAIPCGEPTNIRPFESREAV"
     gene            5603..6391
                     /locus_tag="ROH59_004771"
     CDS             5603..6391
                     /locus_tag="ROH59_004771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HDX4807160.1"
                     /translation="MTVQISAESLSPLHHNQLPVITTELLASLYGTEVNGIQQNFKRN
                     IARFVVGKHFFKLEGNELRDFKNRLTDSQSVAKHTRSLILWTERGAARHAKMLETEQA
                     WEVFEKLEDCYFSQRPERRSTTTDDRTPLRDAVNILVGKKGMMYPDAYTMIHQRFAVS
                     HIEQLSQTQMLEAIEYIHCLLLDENHPTIPDFSFITTIKNGKVTGMRHVAKGEHLMTF
                     DAFKEIAERAGYLVIHSDNLRSMTLDKLMVMGKKSAISVANSAF"
     gene            complement(6566..7489)
                     /locus_tag="ROH59_004772"
     CDS             complement(6566..7489)
                     /locus_tag="ROH59_004772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1311 domain-containing protein"
                     /protein_id="HDX4807161.1"
                     /translation="MRLKYSVLLLAIALTGCDNKKDEIGCSSEITQSALMDLLKKSAY
                     EGLSEQVDKYPDVTNQTKRSTLDKIKLAISEISTTSSDTGSTMKTCEGTVTMTLSANE
                     YVQLSDAYRKNFNRNLDKQMESLFLENNANAFSKRITYTVQATDDQKNVFVKTSTDNP
                     ISVGAALLTSLSIITPIVEQQKIQQAKDAQQSQIEAEQQVQLRAQEQAKYEAEKQIER
                     QAQLQPQKADNLDQSRMAFANADSDLSTVWSKLTPAKKKDLLPSQRQWIKTKDAMCGK
                     VSMQGTDAEVKKMVDCQTQMTLSRIAFLRNQ"
BASE COUNT         2160 a         1758 c         2044 g         1989 t
ORIGIN      
        1 actgaactat tttgtctggt ttttggcttc aagtagttct tttagcagta gatcgaagtg
       61 ctctcttttt tcttttagct cattgattaa tttatttttt tcgctctcag gcagtcctct
      121 gaatagttgc agtagagcct gttcttgcgg ggttagttct tgattgtaat tacccgggtg
      181 tagtgtggat tcatccaaat attccccttc attcatgaag aaaaaatgaa cagggtatcc
      241 ggtcactttt gctagcttgt ctaatttatc ttttcttgga gttaccccat tacaccatgc
      301 ctgaactgat tgagccgtaa ccccaatatg gcgagctaac tcagattgag accagcctaa
      361 gtcttttaga atccgttgta gtcggctagc aaaagccatg tttttcgttt ttgtgttcat
      421 accgtaagga tacaaggttt aattgtaggg agcattgcaa atataatttg taattacagt
      481 tattgtttgt aatgatgacg cggacacaag gagtccatat ggataaacaa ctgcaagaca
      541 aaattctttc cgtaatgagt caatccgagt tagggcggcg attagggaaa aaaccacaaa
      601 cggtaagcct ctggttcaaa ggacgggttc ccggtgaaga ggttttgcgc acatctgaag
      661 ctcttgaatg gcgcgtgacc cctcatgatc ttagaccgga tctttaccca aacccagatg
      721 acagcttgcc taaaacggaa gcagcttaac tgttggtgag ccccaaatct gattaagcgt
      781 aatcaatttt tagcgacagg agacgctatg gaaaaccaag aggaattaca aaaagagatt
      841 ttgacctggg cggcaagggc agggcaggaa ctcgtcacga ttgaaatctg ccgggcctgg
      901 ttcagtcagg gacgcaatga tgagttgaga ctacatgaat ttgaggacgc ggacggcaac
      961 gtggactgga gagccatcaa caacaatcgg cagaaaatct ttcgctggtt acgtggcgag
     1021 acaacggcgg cgcgccgaaa aactcaggtg ctggccagtg tgatgaaagc cgtgctaccc
     1081 gcagaacggc gggcacgtct ggagtcgccg ggcgatcccg ttttgctggc aacgctggcg
     1141 gcaaaagaag gggtggaagc gattaacgct gtacatctcc acttcgcgcc agagttaact
     1201 attcaggaaa ttgacgaagc aatagcggcg ctggtagcga cgcgaggagc agtgatacgc
     1261 actgcgcaag accaccatgc atgagcgcct gaccagcgtt taacttatac cgaggaaaga
     1321 ccgatgttaa gacatattga ccgcattacc tggcgtaacg gctggcacct gaatggacgc
     1381 ccggcacatg ttgcagagat ccgccccata ttcgatggcc gcgtcgcagc tgcacgttct
     1441 gtatgggaaa agtacgaaga agaaaaagcg aaactgcgtg agcaaaatct ctctggcgct
     1501 gcctatgagg ctggctgtcg cgttctctca gaggctttgg gcatatgaac atcctcccgt
     1561 tacttgatag acccatagcc ttccagagaa gttttatccg tcttgaaatg ggcgtgactg
     1621 ccgcattgtt tctgtcgcag ttgacgtact ggacaaacag aacaactgac gacggctggg
     1681 tatataaaac ccaggatgag tgggaagagg aaacagggct ttcacgatac gagcaggagg
     1741 gcgcgcgcaa aaaactacgt ggtctcggcg tcttgctgga acgtaaacag ggcttgcctg
     1801 ccaggctgta ctacaaaatc gataatgatg tgttgtgcca gctacttacg tccgcataca
     1861 aggatgcgga aaaaccacat acaggtgagg ggaaaaccac caggcctgta cgtggaaaac
     1921 caacaaacat tcttacagag aatactacag agattattac tgatggtgaa tcggctgacg
     1981 ccgacaccca acaacctgcc gaccagagaa taaattatca ggtgatactc gatacctatc
     2041 acgagatttt gccagagatg ccaccagtga aaatcctcac tgacggcaga aaaaaacacc
     2101 ttcgcacttt ctggaaaaaa ttcaatttca atgagtcccg ttggcgggcc tatctggaat
     2161 ttatcggtgg caattgtcgc tggatgctgg aggacaggcc aaatggcagg ggaggattct
     2221 ggcggcgtaa aaatcttgat tatctgatta ccgaacgctg ctatgtttcg gtcaaggaag
     2281 aacgcgcaaa tgataaataa cgcgattgca ctgtacagcg ttgacgcaga acaggctgtt
     2341 ctgggctgtc tgatgctgaa taccgaccac gacagaacca atgcggtatt tgcgttactg
     2401 aaaccggaaa cgttttatat caatgcgcat caggttatct accgggagat caaaggatta
     2461 tttcaagctg ataaaccaac tgacctgata acactgaccg aactgatgga atcgaagggg
     2521 ctgtatgagc gcgtgggggg attcgcatac ctggctgaaa tgagtaaggc ggcgattccg
     2581 gcctcaatgg tcaactacgc gaaaattgta cgtgaaaaag ccattcttcg ttatgccgtg
     2641 gaaaagttga attcttgtct ggagattatg atccagcctg cagatatgac tgctactgac
     2701 aggatcaccg ccgttcagca agtgattggg caggtggccg aacattcccg taccgggcat
     2761 aagggcggtt tgcgtccggc aagtgaagtc gtcgatgact ggatagatga ccttgagcgc
     2821 cgtttcaatg atccagcaca tgcagccgga ctaacgctcg gaatcgaaag ccttgatcgc
     2881 ttaatggcac caaagcaggc gttaagaggt tcattggtcg ttattggtgc ccggccaaaa
     2941 atgggcaaga cagccgcgtt taataaaatt gcggtgcatt ttgctctgaa tcatcgtttg
     3001 ccgacgctgg tatttagcct ggaaatgact gacagaagtc tcattgaacg catggttgcg
     3061 caggaagcaa aggtcaattc ggagattttt tatcttggcc ctaacgatga atctgaattg
     3121 agtctcgcaa tagcaaaggc gggggagatt gccgaatcca acatgatgat tgacagcacg
     3181 gcaggtgtaa cccttgcgca tattgtcgct gaatgtcgaa aagttaaacg gatgcgtggc
     3241 tcggttggcc tggtggcaat tgactatttg acgctgatga agaccgaatc ggcagagcgt
     3301 agggatattg cgtatggcga tatcacaacc ggtttgaaga acctggcaaa agagctggat
     3361 tgtgttgtgg tcctgctgac gcaactcaac cgaaagcttg aagaacgtgc cgataagcgg
     3421 cctaacccga gcgacagtaa agataccggg cagatcgaac aagattgcga tgtctggatt
     3481 ggcctctatc gtgatgctgt ttataacgaa aatgccgacc caaatctcat ggaaatgttg
     3541 ctacgtctga accgcgaagg accatcggga acagcctatg ccctgatgaa aaatggctca
     3601 gttattgata tcagcgatga ggaggtttat cgccttacca acgaccgctc agaaaaaaat
     3661 aaacgttatt cccgtagcga taattctcgc acaaatgaat tttaaccacg cctgaccagc
     3721 gtgaaataac cgaggaaaga ccaatgacca ccactccagg caaattagag tacccgtcgg
     3781 acaaaggaca catagacgac ggtaaaaact atctcgacgt cattttgtgg aatatgaacg
     3841 tcgggccacg tgcgcgcact cgcgcggttt ttgtgccaag acctaaagca ggcaattttt
     3901 caacccctgc taagcctgcc cgtcaggcat ccgtagccgc agcgccagca gtgaaacgta
     3961 agggcaaaac gcacaccggg atcgcgattc gcagaaatgg tgagcggcaa gtgaaactcc
     4021 acgaaacagc gacaacctgg tgtgcctcac cgcatgaaac ttacgacaag ataaccgggc
     4081 agcgcattgg cgcgcctggt cgctgccgcc tgctgctgag ttccatcact ccgatagcaa
     4141 agaaaggggc gtgatatggc cgggcaatca gattacctgc cgcccggctt accacacaac
     4201 cgcgccaaat ggccccagga ataccagctt aaagagcact acgacatgcg agcggcggcg
     4261 ctgatccgcc aactctttga gaaacgtatt ccgaggggaa gcgtgattga gcaaatcgga
     4321 atgacgccag atacgtaccg ggaatttttc agagagcgtc tgaactactg gagaggggtg
     4381 atggaacaat gaaatacaaa cggtgggtgc gtgcggaagt cgtaatcatc aaacaatgtg
     4441 cgggcagcat gacagttgaa cgtatagggc agcttattgg cagaaccggt gcagcggtac
     4501 gcacaaaagc gcgcgagctg aaaatctgta tgtatctgcg gggtaattat caccagtcag
     4561 tgaaatacct ccaggaagat atcgagctgg caagggaatt acatcagtcg ggtattaatc
     4621 gccaggatat cgcagaaaaa ctcgaaatgc cgatcggagc ggtgaatcag tttgtttatt
     4681 ttgagcggag aatttcatga aagaactttt tcttgcattt gtgccccggt ttattaatga
     4741 ccagatcgca ctgactgata atggtgaaca atatgaaatt gcctgcagca tggtggatgt
     4801 gaatcctggc gaacggtatg acgcgatgtg tgacctgaaa atatttacct ggctgggttg
     4861 ggctattccg tgtggagaac caaccaatat tcgtccgttt gagagcaggg aggctgtatg
     4921 agtgaattga aaatacgtcg caaggcaata gcacgcgtta aaaatctatt accagtgcct
     4981 gtcaaatatc gtttttgtgg tgggaatgta cggattggta cggatgtatg gtgattgcgg
     5041 agtgacgtaa aacgaatcgt tgtgggtgta atatcgtcaa tatcattggt ttcccggagg
     5101 gaaaggacat gtttggcgat aaactggagt taccacggaa cgggcggata gtgctctata
     5161 tttcagatta caaagtaacc cgggctgagg tgttggaacc ggaaaaacat ctggtcacgt
     5221 taccggacat tattgagttg tataagcggg tcggatatgt ggacttgcat cgcgatgatg
     5281 ttcccgttga gtgtatggaa tgtgaacacc ggaggtttga agttgattga attgacttag
     5341 aaaaagtccg gggctatagt ttccgcgcag ccgcaaaatc ggttgccggg attggcgtcc
     5401 cggatatcta agtgacgcat agccgcgtta gcggtttttt tatgtgttag gcacggccac
     5461 attcgcatta tggtgggctg tgtgggggct tctgtggaag cgccgggttc acttagccgg
     5521 ttacgccaac cctgcacagc tcaccaccag atgattggcg tcgctggtgg tgatgaaaaa
     5581 aacactaagt gaggccactg cgatgacagt ccaaatatct gcggaatccc tttctccgct
     5641 acatcataac caacttcccg tcatcactac tgaattgctt gccagtttgt atggcacgga
     5701 agtaaatggt atccagcaaa acttcaagcg caacatcgcc agatttgtcg taggaaagca
     5761 tttttttaag ctggaaggta atgaattacg cgacttcaaa aacagactga cagatagtca
     5821 gtcagttgct aaacataccc gatccctcat tctctggaca gaacgcggcg cagctcgcca
     5881 tgccaaaatg ctggaaacag aacaggcctg ggaagttttc gaaaagctgg aagattgtta
     5941 ttttagccag cgtccagaga ggcggagtac aactaccgat gaccgtactc ccttgcgtga
     6001 tgccgttaat atactggtcg gcaagaaagg catgatgtat cccgatgcct acaccatgat
     6061 tcatcaacgc ttcgccgtct ctcacataga acaactgtca cagacgcaaa tgttagaggc
     6121 gattgaatac atccactgcc tgctactcga tgaaaatcac ccaaccattc cagatttttc
     6181 ttttatcacc actatcaaaa atggaaaagt gaccgggatg cgccatgttg ccaaaggcga
     6241 acatctgatg acctttgacg ctttcaaaga gatcgctgag cgggcagggt atctggtgat
     6301 ccacagcgac aatctgcgaa gtatgacact ggataaattg atggtaatgg ggaaaaagtc
     6361 ggctatatcc gttgctaatt cagcattttg acaggttgtt tggggcggaa atactctatt
     6421 tgcgcttaaa aaggtatttg accacgacca gcacgagacc gaatacctct gtcaaagtac
     6481 cgcccatata aaacagttac atatgcactt gatgactaag ctggcaccag gttaacacct
     6541 ggcgccagct tgaaggagac ttcagttatt ggtttctgag gaaagcgatt cttgaaaggg
     6601 tcatttgcgt ctggcagtcg accattttct tgacttcagc atctgttccc tgcattgaaa
     6661 ctttaccgca catagcatcc ttagttttga tccactgacg ctgagaaggc agcaaatctt
     6721 ttttcttcgc cggggttaac ttgctccaga cggtactcaa atcagagtcg gcattcgcaa
     6781 atgccattcg ggactgatca aggttgtcag ctttttgcgg ctgaagttgt gcctgtctct
     6841 ctatttgctt ctccgcctca tacttagcct gttcttgcgc cctgagttgc acctgttgtt
     6901 ccgcttcaat ttgactctgt tgggcatcct tagcctgctg gattttctgc tgctcaacga
     6961 tcggggtgat aatggaaagc gatgtcagta aagcggcgcc cactgatatc ggattatcag
     7021 tagaggtttt tacaaaaacg tttttctgat cgtcggtcgc ctgcacggtg taggtgatac
     7081 gttttgaaaa ggcgtttgcg ttgttctcca aaaacaggct ttccatttgc ttatcgagat
     7141 tacgattaaa attctttctg taagcatctg aaagctggac gtactcgttc gcagatagag
     7201 tcatcgtcac ggtcccttca caagttttca ttgtgctgcc cgtgtcactt gatgttgtgg
     7261 agatctcaga gatggctagt ttgatcttgt ccagtgtgct tcgtttggtc tgattagtga
     7321 catcagggta tttatcgacc tgttcagaga gtccttcata agcagatttt tttaataaat
     7381 ccatgagagc tgactgggtt atttccgaag aacaaccgat ctcatctttt ttgttatcac
     7441 agcctgtaag ggcaatggcg agtaagagta ctgagtattt taatctcatg aattcccttt
     7501 agagtaagga ttggttttta agacgcggtc tgtaatcagt cccgagagct acagtaaaca
     7561 acgctgagca ctgaacgcat cacaggtaag gtaaaaggtg atatcggcaa aggctgtgaa
     7621 acctttaatt caacagatgg gaacggtatg cgcaggatcc tgtaacgacg ctcccaaaac
     7681 cggaaacctg taaggcatgt tttcgctgct gaacttaata tacgaacctg cactatcatg
     7741 aacatatttt atatcgttat accccgagtg attgtgcccg gcaatggata gtgtcctgga
     7801 ggaactattt ctactgtaaa aggtagatat ttaatttcag ttttgaatta ttccctgctg
     7861 ttaataacaa tggctgtata tggcaccgag taggcatttt ttcgcttact gaagggcagc
     7921 tgtgagcgag gaacagactt tccctacttc g
//
LOCUS       DAPOXO010000151         7720 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPOXO010000151 DAPOXO010000000
VERSION     DAPOXO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7720
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.151"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            205..918
                     /gene="ydiV"
                     /locus_tag="ROH59_004773"
     CDS             205..918
                     /gene="ydiV"
                     /locus_tag="ROH59_004773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HDX4807162.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQDLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLDRDNFAG
                     ELLKYPFIELLINENYPHFNEGKDNRDLLSLSQMYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTPEILAQIIPFDFHAL
                     QGCLWPAVPINQITTLVQR"
     gene            981..2417
                     /locus_tag="ROH59_004774"
     CDS             981..2417
                     /locus_tag="ROH59_004774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HDX4807163.1"
                     /translation="MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIP
                     SSLFKNGAGVWGGENLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TVEPGAMLMRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWPHLADDEDKYRLW
                     FTDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDGLNEALDSYQQVLLTHYGQRMRQKLG
                     FMTELKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRGRLQQDEITDNERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRDDDYVSRPPDWGKRLEVSCSS"
     gene            complement(2421..2612)
                     /gene="hemP"
                     /locus_tag="ROH59_004775"
     CDS             complement(2421..2612)
                     /gene="hemP"
                     /locus_tag="ROH59_004775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HDX4807164.1"
                     /translation="MRYTDSRKLTPETDANHKTASPQPIRRITSQTLLGPDGKLIIDH
                     DGQEYLLRKTQAGKLLLTK"
     gene            complement(2744..3790)
                     /gene="aroH"
                     /locus_tag="ROH59_004776"
     CDS             complement(2744..3790)
                     /gene="aroH"
                     /locus_tag="ROH59_004776"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HDX4807165.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            complement(3947..4780)
                     /gene="ppsR"
                     /locus_tag="ROH59_004777"
     CDS             complement(3947..4780)
                     /gene="ppsR"
                     /locus_tag="ROH59_004777"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HDX4807166.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     Y"
     gene            5113..7491
                     /gene="ppsA"
                     /locus_tag="ROH59_004778"
     CDS             5113..7491
                     /gene="ppsA"
                     /locus_tag="ROH59_004778"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HDX4807167.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGVDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(7548..>7720)
                     /locus_tag="ROH59_004779"
     CDS             complement(7548..>7720)
                     /locus_tag="ROH59_004779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="acts in anaerobic beta-oxidation of fatty acids;
                     possible ligase/synthase involved in anaerobic growth on
                     fatty acids; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cyclohexanecarboxylate-CoA ligase"
                     /protein_id="HDX4807168.1"
                     /translation="EVVAFFSRKRVAKYKYPEHIVVIEKLPRTVSGKIQKFLLRKDIM
                     RRLTQDVCEEIE"
BASE COUNT         1890 a         1828 c         2021 g         1981 t
ORIGIN      
        1 ctcctgaata cagtagtatt ttgcagacag aaattccgta aatggattat tcgtttataa
       61 tcaggataat ctaaaaaaaa ggacccctga aaaagtggtt aacatggaac aaatgaaagt
      121 tactccttct gtaattgtta tgtcttatgg cctcatccct tttagccgga tactgaaaaa
      181 catccttcga gagggacggt taccatgaag atttttttgg agaatcttta tcattctgat
      241 tgctatttcc tgccgataag agataaccag caagaccttg tcggcgttga gttaattacc
      301 catttctcca gtgaagatgg tacggttcgt atcccgacga gtcgggttat agcgcaactt
      361 accgaggagc aacattggca attattttct gaacagttgg aattactaaa atcatgccaa
      421 cactttttta ttcaacataa actctttgcc tggcttaatt taacgccaca agtggctaca
      481 ttattattag acagggataa tttcgcaggc gaactattaa aatatccgtt tattgaactg
      541 ttgattaatg agaattaccc gcatttcaat gaaggaaaag ataatcgcga tcttttatcc
      601 ttatcgcaaa tgtatcccct tgtgttaggt aatttgggag caggtaatag cacaatgaaa
      661 gcggtgtttg atggtctttt cacccgcgtc atgctggata aaagttttat tcagcaacaa
      721 atcacgcatc gctccttcga accgtttatt cgtgcgatcc aggcgcaaat ttccccttgt
      781 tgcaattgca tcatcgcggg gggcattgat acgccagaaa tattggcaca gattataccc
      841 tttgatttcc atgctctcca gggatgcctg tggcctgcgg ttcctataaa tcagataacg
      901 acgttggttc agcgataacc ctcctgtttg ctggtgttta ggacgagagt aaccgtctac
      961 actatcaaac aggaggatct atgaccctgt cttttattac ccgctggcgc gatgaattgc
     1021 cagaaaccta tacagcactt tcccctacgc ctttaaataa tgcccggctg atttggcata
     1081 ataccgaact ggctaacacg ctgagtattc catcgtcgct gtttaaaaat ggcgcaggtg
     1141 tctggggcgg cgaaaaccta ctgcctggta tgtcaccact ggcgcaggtt tacagtggtc
     1201 atcagtttgg cgtctgggcg ggccaactgg gtgatgggcg cggcatttta ctcggcgaac
     1261 aactgcttgc tgatggcact acaatggact ggcatctgaa aggtgctggc ctgacgcctt
     1321 attcgcgaat gggtgatgga cgggcggttt tacgttcgac gatacgagaa agtctcgcca
     1381 gtgaggcgat gcattatctg ggcattccga cgacccgcgc tttaagtatc gtcaccagcg
     1441 attcgccagt gtatcgggaa acggtggagc caggcgcgat gctgatgcgt gtggcaccaa
     1501 gtcatctgcg ctttggtcat ttcgaacatt tttactatcg ccgcgagccg gaaaaggttc
     1561 gtcagttagc tgactttgcc attcgtcatt actggccaca tcttgcagat gatgaggaca
     1621 aataccgtct ctggtttacc gatgttgtcg cacgtaccgc ctcgttaatt gcccaatggc
     1681 agactgtcgg ctttgctcat ggggtgatga ataccgacaa catgtcgctg ctggggctga
     1741 cgcttgatta cgggccgttt ggttttcttg atgattacga acccggtttt atttgtaatc
     1801 actcggatca tcaagggcgt tacagctttg ataatcaacc tgccgtcgcg ttgtggaatt
     1861 tacagcgtct ggcgcagaca ttgtcaccat ttgttgccgt agatggcctg aatgaggccc
     1921 tggacagcta tcagcaggtt ttgttgacgc attatggaca acggatgcgg cagaaactgg
     1981 gcttcatgac ggagctaaaa gaggataacg cgctactgaa tgaattattc agtctgatgg
     2041 cgcgagagcg cagcgattat acccgcacat tccgcatgct gagtctgacc gagcagcaca
     2101 gcgcggcgtc accgctacgt gatgagttta ttgatcgtgc agcatttgat gactggtttg
     2161 cccgttatcg ggggcgtttg caacaagacg agattaccga taatgagcgt cagcaactga
     2221 tgcaaagcgt taacccggct ctggtgttgc gcaactggtt ggcgcaacgg gcgattgaag
     2281 cggcagaaaa gggtgatatg acggaattgc accgcctgca tgaggcgttg cgaaatcctt
     2341 tcagcgacag agatgatgac tatgtcagtc gtccacctga ctggggtaaa cggctggaag
     2401 tcagctgctc gagttaaagg ctacttggtc aacagcagct tgccagcctg agttttacgg
     2461 agcagatatt cttgtccgtc atgatcgata atcagtttgc catccggacc taacagtgtc
     2521 tggctggtaa ttcgccggat gggctgcggg gaagcggtct tgtgattggc atccgtttca
     2581 ggcgtgagtt ttctgctatc cgtataacgc ataaaaatta ataataattt atataacaat
     2641 gattcttatt atcaatatta tggagggcca gagcaagcag taatttgttg agaagacaac
     2701 aagttgcgca gaaatgccca tcctgtcagg aatgggcacg cattcagaag cgggtatcta
     2761 ccgcagaggc gagtttttcg accaggcgtt cggtatcttc ccagcccaga cacgggtcgg
     2821 taatggattg accgtaagtg agcggctgac cgccgacgat tttttgcgtt ccttcgcgca
     2881 ggaaactttc cgccataatt ccggcaatcg ccgtagagcc attgcggatt tgctgacaaa
     2941 tatcctcaca aacttctaac tggcgacggt gctgcttctg gcagttaccg tggctgaaat
     3001 ccaccaccag atgttcaggc aaatcaaatt cgtgcagcgt atcgcaggct gcggcgatat
     3061 catcggcatg ataattcggt tttttgccgc cacgcataat aatgtggcca tacgggttgc
     3121 cgctggtctg atagatggtc atctgaccgt ttttgtctgg cgagaggaac atatggctag
     3181 cgcgggctgc gcggatagca tccacggcaa tccgcgtgtt gccatcggta ccatttttaa
     3241 aacccaccgg acaggagagt gccgaagcca tttcgcggtg gatctgactt tcggtagtac
     3301 gtgcgccaat cgcgccccaa ctgattaaat cagcaataaa ctgaccggtc accatatcga
     3361 ggaactcagt cgcggtaggg acgcccagct catttacctg taaaagtaat ttgcgcgcca
     3421 gctccagacc gtgatttacc cgatagctac cgtttaaatc tggatcggag atgagtcctt
     3481 tccagccgac aaccgttcgt ggtttttcaa aataggtgcg cattacgatt tccagccgtg
     3541 actggtactg gttgcgcagc gactgcagac gggtggcgta ctccatcgca gcggtgagat
     3601 cgtggatcga gcaggggcca ataatgacca acagtcgctt atcttcacca ttcagtattt
     3661 tttcaattct acggcgggag tcggtgacat gggtggcgac gccaggcgtt acgggatacc
     3721 gtagcgcgag ttcggcgggc gttaccaggc tctcaatacg cgcagtacgg agttcgtcag
     3781 ttctgttcat tacaagtctc agaaatttgt tgcttctacg gcaggactac cgggaagtga
     3841 tgcgcatcac gataaaccaa tcgcagctga tttcaagtgc gaggtgtgtc acacctcgcc
     3901 gggtggttag catgataaca aaaaaacaag ctaatgcact agttctctag tacattcggc
     3961 ggctaaggcc catgatatcg aggatcttgg tggcaatctc ttctaccgaa taattggtac
     4021 tgttaatcca cgggatctga tttttacggt acaacgcttc cacttccgcg acttccatcc
     4081 tgcactgacg aagcgaggca tagcgactgt tctcccgacg ttcctcgcga atcgccgcca
     4141 gacgttccgg gtcgatagtc aggccgaaca atttatgctg aagtggtttg agcgacgcgg
     4201 gtagcaccag attatccata tcatcggcaa taaaggggta gtttgccgcg cggataccaa
     4261 attgcattgc cagatacaga ctggtggggg ttttaccaca gcgagaaaca ccgagcagga
     4321 tcacctgagc ctggtccaga ttgcgcaacg aaataccgtc atcgtgggca agggtgtaat
     4381 caatcgccgc aatgcgcgca tcatatttat tgagattatt agggttaagg ccatgggtac
     4441 gatgagcaat cggcgttgga tccagtttca tctcttgttg tagtggggca accagcgcct
     4501 gaacgatatc ctggcaaaag ccttcacttt gcaagatgat agcgcgaatc tccggcaaca
     4561 cgatggagta gaagaccagc gggcgcacac ctgtctggtg ataaattgcg tcaatctgat
     4621 ccttcactgc ccgtgcacgg ctctcatttt cgacaaacgg cagcgtaatg ctgctgatag
     4681 tgacgggaaa ttgtgacatt actgcgtgtc ctaatacctc cgcagttatt gccgtaccat
     4741 cagaaatata aaaaacgtgg cgatcaacag cattatccat tttgttcttc ccgtgatgca
     4801 gacataattc tatgaaagca taaattaaaa acgcacagaa gcgtagaacg ttatgtctgg
     4861 tttataaaat gaaacttaaa ttttattttt tatgaaaaca gcatttcatt tttatggttt
     4921 cgtttatacc gatggtttat gtggaaattg tcgaagagag cagatttgcg caacgctggg
     4981 atcagtctta aaaagtaaaa aaatatattt gcttgaacga ttcaccgttt ttttcatctg
     5041 gttaaatatg caaagataaa tgcgcagaaa tgtgtttctc aaaccgttca tttatcacaa
     5101 aaggattgtt cgatgtccaa caatggctcg tcaccgctgg tgctttggta taaccaactc
     5161 ggcatgaatg atgtagacag ggttgggggc aaaaatgcct ccctgggtga aatgattact
     5221 aacctttccg gaatgggtgt ttccgttccg aatggtttcg ccacaaccgc cgacgcgttt
     5281 aaccagtttc tggaccaaag cggcgtaaac cagcgcattt atgaactgct ggataaaacg
     5341 gatattgacg atgttaccca gcttgcgaaa gcgggcgcgc aaatccgcca gtggattatc
     5401 gacactccct tccagcctga gctggaaaac gccatccgcg aagcctatgc acagctttcc
     5461 gccgatgacg aaaacgcttc gtttgcggtg cgttcctccg ctactgcaga agatatgccg
     5521 gacgcttctt ttgccggtca gcaggaaact ttcctcaacg ttcagggtgt tgacgccgtt
     5581 ctcgtggcag tgaagcatgt attcgcttct ctgtttaacg atcgcgccat ctcttatcgt
     5641 gtgcaccagg gttacgacca tcgtggcgta gcgctctccg ccggtgttca gcggatggtg
     5701 cgctccgacc tcgcatcttc tggcgtgatg ttctccattg ataccgaatc cggctttgac
     5761 caggtggtgt ttatcacttc cgcatggggc cttggtgaaa tggtcgtgca gggtgcggtt
     5821 aacccggatg agttttacgt ccataaaccg acacttgcgg cgaatcgccc ggctatcgtg
     5881 cgccgcacca tggggtcgaa aaaaatccgc atggtttacg cgccgaccca ggagcacggc
     5941 aagcaggtta aaatcgaaga cgtaccgcag gaacagcgtg acatcttctc gctgaccaac
     6001 gaagaagtgc aggaactggc aaaacaggcc gtacaaattg agaaacacta cggtcgcccg
     6061 atggatattg agtgggcgaa agatggtcac accggcaaac tgttcattgt gcaggcgcgt
     6121 ccggaaaccg tgcgctcacg cggtcaggtc atggagcgtt atacgctgca ttcacagggt
     6181 aagattatcg ccgaaggccg tgctatcggt catcgcatcg gcgcgggtcc ggtgaaagtt
     6241 atccatgaca tcagtgaaat gaaccgcatc gaacctggcg acgtgctggt tactgacatg
     6301 accgacccgg actgggaacc gatcatgaag aaagcatctg ccatcgtcac caatcgtggc
     6361 ggtcgtacct gtcacgcggc gatcatcgct cgtgaactcg gcattccggc ggtagtgggc
     6421 tgtggtgatg caacagaacg gatgaaagac ggcgagaacg tcactgtttc ttgtgccgaa
     6481 ggtgataccg gttacgtcta tgcggagttg ctggaattta gcgttaaaag ctccagcgta
     6541 gaaacgatgc cggacctgcc gttgaaggtg atgatgaacg tcggtaaccc ggaccgtgct
     6601 ttcgacttcg cctgcctgcc gaacgaaggc gtgggccttg cgcgtctgga atttatcatc
     6661 aaccgtatga ttggcgtcca cccacgcgca ctgcttgagt ttgacgatca ggaaccgcag
     6721 ttgcaaaacg aaatccgcga gatgatgaaa ggttttgatt ctccgcgtga attttacgtt
     6781 ggtcgtctga ctgaagggat cgcgacgctg ggtgccgcgt tttatccgaa gcgcgtcatt
     6841 gtccgtctct ctgattttaa atcgaacgaa tatgccaatc tggtcggtgg tgagcgttac
     6901 gagccagatg aagagaaccc gatgctcggc ttccgtggcg cgggccgcta tgtttccgac
     6961 agcttccgcg actgcttcgc gctggagtgt gaagcagtga aacgtgtgcg caacgacatg
     7021 gggctgacta acgttgagat catgatcccg ttcgtgcgta ccgttgatca ggcgaaagcg
     7081 gtggttgagg aactggcgcg tcaggggctg aaacgtggtg agaacgggct gaaaatcatc
     7141 atgatgtgtg aaattccgtc caacgccttg ctggcagagc agttcctgga atatttcgac
     7201 ggcttctcaa ttggctcaaa cgacatgacg cagctggcgc tcggtctgga tcgtgactcc
     7261 ggcgtggtgt ctgaactgtt cgatgagcgc aacgatgcgg tgaaagcact gctgtcgatg
     7321 gcgattcgtg ccgcgaagaa acagggcaaa tatgtcggga tttgcggtca gggtccatcc
     7381 gaccacgaag actttgctgc atggttgatg gaagagggga tcgatagcct gtctctgaac
     7441 ccggacaccg tggtgcaaac ctggttaagc ctggctgaac tgaagaaata aaataaatac
     7501 ccggcggcgt tttgtcgccg ggtttatgtg atccccgaag atgaaactta ttcaatctct
     7561 tcacagacat cctgagttaa tcgccgcata atatctttcc ttaacaaaaa cttttgtatt
     7621 ttacctgaga cagtgcgcgg tagtttttcg attaccacga tatgttcagg atatttatat
     7681 tttgcgaccc gtttacggct aaaaaaagcc accacctctt
//
LOCUS       DAPOXO010000152         7658 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPOXO010000152 DAPOXO010000000
VERSION     DAPOXO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7658
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.152"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            61..471
                     /locus_tag="ROH59_004780"
     CDS             61..471
                     /locus_tag="ROH59_004780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDX4807169.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPSCGTGVYSREGGLQEGNWKDRN"
     gene            755..2374
                     /locus_tag="ROH59_004781"
                     /pseudo
     CDS             755..2374
                     /locus_tag="ROH59_004781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            2454..2746
                     /locus_tag="ROH59_004782"
                     /pseudo
     CDS             2454..2746
                     /locus_tag="ROH59_004782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312320.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
     gene            complement(2786..3820)
                     /locus_tag="ROH59_004783"
     CDS             complement(2786..3820)
                     /locus_tag="ROH59_004783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase"
                     /protein_id="HDX4807170.1"
                     /translation="MKDYLQTVTGPVAREDMGLTLPHEHLFNDLSSVVDAPCYPFSQR
                     LVDKKVTAEIQWALKHDPYCCADNMDRKPIEDVIFEINNFISLGGRTIVDATGSESIG
                     RDAQALREVALKTGLNIVASSGPYLEKFESQRIHKTVDELAATIDKELNQGIGDTDIR
                     AGMIGEIGVSPTFTEAEHNSLRAASLAQINNPHVAMNIHMPGWLRRGDEVLDIVLGEM
                     GVSPNKVSLAHSDPSGKDVAYQRKMLDKGVWLEFDMIGLDITFPKEGIAPGVQETADA
                     VAHLIELGYADQLVLSHDVFLKQMWAKNGGNGWGFVPDVFLAYLAERGVDKTILKKLC
                     IDNPGRLLTA"
     gene            complement(3823..4788)
                     /locus_tag="ROH59_004784"
     CDS             complement(3823..4788)
                     /locus_tag="ROH59_004784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX4807171.1"
                     /translation="MKKNKYSTPLWMLATILAGMLSPMQSAVNGQLGHWLQDGNACAV
                     ISFASGLVVMFFIIMARKETRQQFAAIPSLIKNRKVPLWNWFAGLCGAMVVFSEGASA
                     SALGVATFQTALISALLLSGLLCDRFGIGVDEKKYFTPYRIIGALFAVIATIFVVSPQ
                     WHSTSFILLAILPFLAGLLAGWQPAGNAKVAEATGSMLVSITWNFIVGFCVLGTALAI
                     RVALGHVTVQLPDVWWMYLGGPLGLMSIGLMAILVRGLGLLMLGVASTAGQLLGSVLI
                     DVLIPSLGNTVYLVTIIGTLFALVGAIVTTIPEYRTSKTMKKMEV"
     gene            complement(4842..5600)
                     /locus_tag="ROH59_004785"
     CDS             complement(4842..5600)
                     /locus_tag="ROH59_004785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDX4807172.1"
                     /translation="MNNTKKSLKVLFIGESWHIHMIHSKGYDSFTSSKYEEGATWLLQ
                     CLKNSQVDVTYMPAHTVQIAFPEDVAQLEQYDAIVISDIGSNTFLLQNDTFYQLRIKP
                     NALELIKEYVNNGGGLLMIGGYLSFMGIEAKANYKNTVLADVLPVTMLDGDDRVEKPE
                     GVIAQPSQPEHPVIKGFSEYPFFLGYNRAIAKENAEVVLTINNDPLLVFGNYHNGKIA
                     CFMSDCSPHWGTQQFMSWPFYTALWVNILTHIAR"
     gene            complement(5614..6828)
                     /locus_tag="ROH59_004786"
     CDS             complement(5614..6828)
                     /locus_tag="ROH59_004786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462448.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDX4807173.1"
                     /translation="MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELAR
                     LGYLTRCHGGAFIVLDSLDTIAKNEIAYALENYDTAQGIKKGHSTMKSQVCVIGSFNV
                     DIISYLPRLPTIGESLLASNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYA
                     INFMNSSKIYKSIIYQTKETQTGTATILVNEGTGDNVIAIYPGANMTMSSDEITIQKE
                     AIINSDVILLQLETNYTALQQAITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNE
                     TEAGLLSGIDVHDLESAKRAAEAIHNKGVKNTVITLGSKGSLAFDGKKFIHSPAFPAV
                     VKNTAGAGDAFNGALASGLAKGKSLESALCYASAFASLAVETSNASDMPEHESVIHRI
                     QSIHYQQTIFTH"
     gene            complement(7024..7362)
                     /locus_tag="ROH59_004787"
                     /pseudo
     CDS             complement(7024..7362)
                     /locus_tag="ROH59_004787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2071 a         1733 c         1837 g         2017 t
ORIGIN      
        1 gtactgcaca cactgccaga ccggaggatt cagtattccc cggacaactc aggaggaaat
       61 atgcgaattc tgaactgtta tatggcgaat gacagcaaag gccattttgt tacggcgaaa
      121 gaagcagcga agcacaaccg ccaggacgtt ttgtgctgtg tgtcctgtgg atgcccgtta
      181 acacttcagc ggggcaatga cggacaacca ccgtggtttg aacatgacca gatgactgtc
      241 gctgagaaaa tcctgctgcg atgcacctgg cttgacccgg cagagaaaga ggcccgtcgt
      301 ttgcatctgc agggtatgac ggttccggat tatacggtga aggtgagaaa gtggttttgt
      361 gtgatgtgtg acgaagatta tgaaggagaa aagtgctgcc cgagttgtgg taccggggta
      421 tacagcaggg agggggggct gcaggaaggc aactggaagg ataggaactg agcggttcag
      481 tcgcggaaat cagttgtaga gctgtaatga tatctccggg agtgctgcgt tggtaggggc
      541 atcccgggat agagaaattt tagcactttg ccctgaatga ttgtagacgt cccgggtact
      601 cgtaccggtc tgagttatta cagttagata ttcacttttt ctcccgcata cttcacatct
      661 gtcaacgacg gatgaaaagt ggttcttccg caacctgggt ggaagaaaat ggatgaaact
      721 ttctggcgaa caaggatcta agctgtttta agttatgggc aacgcaatgc actctcttaa
      781 gacacttcta cagttacctt gcggatggcg atgcagtcga caaattatta gctctgacgg
      841 tataaccctc catctccacg gaaaacgcaa aacagcacaa tgtcctgaat gctttaagcg
      901 tagcgactct gttcatagtt gtcgtcggcg ccggatacag catctaccct gctcagggca
      961 gacgctatgg cttgtatttt ccgtccgcca ctggtactgc cgtaacccgg cttgttaacg
     1021 taaaattttt gccgagtcgc ttgctccctt cgccggttca caccagcagt cttcacaggc
     1081 gttacaaaat ttacaacgtc aactgggatt aatagctgga ggtgaggctg gaaaacgggc
     1141 tgcaacggca gcgggtctcc gttgcagtgc tgatactctt cttcgcaggg ttatcaatac
     1201 cccggagacg aaacagtcag gcgcgcctca tgtcggtatt gatgagtggg cgtggcatcg
     1261 gggccactgc tgcggtatgt taatagtcaa tcttgatact caccgtcccc tcgtcctgct
     1321 tcccggccgt gatcagcgta cgctggcgac ctggttcaga aaatatccgg aaatacaggt
     1381 tgtctcgcgt gatcgcagtg gagtctatgc gacagcagca cgtgaaggtg cacctcaggc
     1441 cagacaggtg gccgatcgat ggcacctgct aaaaagtatt ggtgatgagc ctgaacgaat
     1501 gatgtacaga catatgcctc tgatacgtct tgttgtcaga gagttatcac tgaagaaatc
     1561 acctgagcca gaaatatctg tgcctgtagc atcgctccgt cgtccggaac gccttaaaca
     1621 gcaaacccgc aaaaaacggc atcagcattg gacagaggtt atggccctgc ataacaaggg
     1681 atgtagtttc agggaaatat cccgtattac aggcctgtcg cgagtgacag tcagtcgctg
     1741 ggtgcgttca ggaacattcc ctgaaatgtc aacccggcct ccaaagcgag ggcttctgga
     1801 cccatggagg gagtggttaa aagagcaacg agaaagtggt aattataatg ccagccggat
     1861 atggcgggaa atggtggccc agggggggac aggcagtgaa accatcgtca gggatactgt
     1921 tgccaaatgg cgtaaaggct ggaacccacc ggttactact gccgcaagac ttccttcagt
     1981 gtcccgggta agccgctggt tgatgccctg gagaataatc aggggcgaag aaaattatgc
     2041 atcccgattt attagtctga tgtgtgaaaa agaaccggag ttgaaaatag cacagcaact
     2101 ggtactcgag ttctaccgta ttctgaaaac ctaaaataaa tcacagctaa gcagctggtt
     2161 cactcgagtt cacgaaagcg gctcagcaga acttcggtgc gtagctgcgg ggatggaagc
     2221 tgatgctgcg gctatatgtg aggcaatcag cagtcgctgg agtaatggtg ttgtcgaagg
     2281 tcatgtaaat cgcctgaagg tgctgatacg ccagatgtat ggtcgagccg gatttgaact
     2341 acttaggcgg agggtaatga gtccactggc atgaaaatct tcacctaggt tgcggaagag
     2401 ccacttttgc actgttcgtg acagtatggc ctttatgtac tcactttgtt accggtagct
     2461 gaatcatcac taccgtgctg caaatggtgg tgaacagcat caattgtgga atgaatgttg
     2521 ccgaagcgac caatgcgcct cgtttccacc atcagtggtt gccggactag ctgcgtgttg
     2581 aaaagggttt agtccggata cgctcaagct gctggaagca aaaggtcaga aagtggcgct
     2641 gaatgaggcg atgggcagca cgcaaagcat tatggttggg tcggatggtg agttgtacgg
     2701 cgcatccgac tcgcgcttgg tggatgattt aacggcgggg tattaattga catcccccgg
     2761 cgcagtgtgc cgggggataa tggttttatg cggtcaataa tcgtccggga ttatcgatac
     2821 agagtttttt gaggatcgtt ttatcgacgc cgcgctccgc cagataggcc agaaaaacat
     2881 ctggaacaaa tccccagcca ttaccgccat ttttagccca catttgttta aggaagacat
     2941 cgtggctgag aacaagctga tcggcgtatc ccaactcaat gagatgagcg acggcatcgg
     3001 cagtctcctg cacccctggc gctattccct ctttcgggaa ggtaatgtct aggccaatca
     3061 tgtcgaattc cagccagaca cccttatcaa gcattttccg ctgatacgcc acgtcttttc
     3121 ctgacggatc cgagtgtgcg agagagactt tatttggcga gacgcccatt tcacctaaca
     3181 caatgtcgag tacttcatca ccgcgacgaa gccagcccgg catgtgaata ttcatcgcca
     3241 catgaggatt gttaatctgt gccagcgagg cagcccgcaa gctgttatgc tcggcttcgg
     3301 taaatgtcgg tgagacacct atttcaccga tcattccggc acgaatatcc gtatcgccaa
     3361 tcccttgatt caattcttta tcgatcgttg ccgccagttc atcaaccgtt ttatgaattc
     3421 tctggctttc aaatttttcc aggtagggac cggaggaagc aacaatattc agacctgttt
     3481 ttaatgcgac ttctcgtaat gcctgcgcat ctcgtccgat agactcagac cctgtggcat
     3541 caacaatggt gcgaccaccg agcgagataa agttattaat ttcgaagatc acatcttcaa
     3601 taggtttgcg gtccatatta tcagcgcagc aataaggatc gtgttttaat gcccactgga
     3661 tttctgccgt gactttttta tcaacaagcc gttgtgaaaa aggatagcaa ggagcatcca
     3721 caacagagga aagatcgttg aacagatgtt catgaggaag tgttagcccc atatcttcac
     3781 gggcgacggg gcccgtcaca gtttgtagat aatctttcat gattatacct ccattttctt
     3841 cattgttttc gaggttctgt attccggaat agtggtaaca attgcaccga ccagtgcaaa
     3901 cagtgttccg atgatcgtga ccagataaac ggtattgccc agcgatggaa ttaatacgtc
     3961 aatcaatact gatcccagta actggcccgc cgttgaagca acccccagca tcagtaaccc
     4021 cagacctctg accaaaatgg ccattaaacc gatagacatt agtccaagcg ggccgccaag
     4081 atacatccac cagacatctg gtaattgaac agtgacgtgc cctaatgcga cacgaatagc
     4141 tagcgctgtg cctaaaacac aaaatccaac gatgaaattc caggtgattg aaaccagcat
     4201 ggatcccgta gcttcagcta cttttgcatt tccagcgggc tgccatcctg caagcaaacc
     4261 agctaagaac ggaagaatgg caagtaagat gaaagaggta gaatgccact gcggtgacac
     4321 aacaaaaatc gtagcaataa ccgcaaataa tgcaccgatg atgcgataag gggtaaagta
     4381 ttttttctcg tcgacaccga taccaaagcg atcgcaaagt aaaccagaca gcaatagcgc
     4441 ggagatcagt gcggtttgaa acgttgcgac cccgagtgcg ctggctgatg cgccttcaga
     4501 aaataccacc atcgctccac agagaccggc aaaccagttc cagagaggaa cttttcggtt
     4561 tttaatcaga gaaggaattg ccgcaaattg ttgccgggtt tcttttcgcg ccataataat
     4621 aaaaaacatc acgactaaac cactggcaaa ggagataact gcgcatgcat taccatcctg
     4681 taaccagtga cctaattgac cattcaccgc tgattgcata ggggagagca tacccgcaag
     4741 aatcgtggca agcatccata agggagttga gtacttattc tttttcatac atcaatcctt
     4801 ctattatagt aaatggggta actggagtta ccccattatt attatcttgc aatatgagtc
     4861 agtatattta cccacaacgc ggtatagaac ggccaggaca taaactgctg tgtaccccag
     4921 tgcggtgaac agtcactcat aaagcaggct attttcccgt tgtgatagtt accaaagacc
     4981 agtaatggat cgttgtttat tgttaatacc acctcagcat tttctttagc gatcgcccgg
     5041 ttataaccta ggaaaaaagg atattcagag aaccctttaa taactggatg ttcaggttgt
     5101 gatggctgtg caataacacc ctctggtttt tcgacacgat cgtcaccatc taacatcgta
     5161 accgggagca catcagccag aactgtattt ttataattgg cttttgcttc aattcccatg
     5221 aatgagagat agccgccaat catcaataac ccaccaccgt tattcacata ttctttaatc
     5281 agttcgagag cgtttggttt tatgcgaagt tgataaaaag tatcattttg tagcaggaaa
     5341 gtattactac caatatcact aataacgatg gcatcatatt gttctaactg tgccacatct
     5401 tcagggaagg caatttgtac cgtatgtgcc ggcatatagg tgacatctac ctgactattt
     5461 ttcagacatt ggagtaacca ggtcgcacct tcttcatatt tacttgaggt aaaactgtca
     5521 tatccttttg aatgaatcat atgaatatgc caggattccc caataaagag cacttttagt
     5581 gattttttgg tgttattcat tctctgtccc ttcttaatgc gtaaaaatag tttgctgata
     5641 atgtatactc tgaattcgat gtatcacaga ttcatgttca ggcatgtcgg aagcattgct
     5701 tgtctccacc gctagggatg caaaggcgct ggcataacac agtgctgatt ccagtgattt
     5761 tcctttcgca agtcctgatg ccagagcgcc gttaaaagca tccccggctc ctgccgtatt
     5821 tttaacgacc gctggaaacg ctggcgaatg aatgaatttt ttgccatcaa atgcgagcga
     5881 gcccttgcta ccgagcgtga taaccgtgtt ttttacccct ttattgtgga tagcttctgc
     5941 agctcgttta gctgattcaa gatcgtgtac gtctatgccg gacagtaaac cagcttctgt
     6001 ttcattgggg gtgatataat caacatcctg aataagttcg ttgacgatat cattataggg
     6061 tgccgggtta ataatgaccg ggatactgtt tttttgcgcc aatgtgatcg cttgttgcag
     6121 agcggtataa tttgtttcga gctgcagaag tatgacatca gaattaataa tcgcttcttt
     6181 ctgaatagtt atttcatcgg acgacattgt catgttggca ccgggataga tcgcaataac
     6241 attatcgcca gtaccttcat taacaaggat cgtggcagtt ccggtttgcg tttctttcgt
     6301 ttgataaatt atacttttat aaatcttaga cgaattcata aagttgatcg cataatcact
     6361 aaagtgatct gtacctactt ttgttatgaa ataaacatca gtatcggcaa agcttgctgc
     6421 cagcgcttgg ttacagcctt ttccccccgg tgaaaatata aaattacttg ccagaagcga
     6481 ttctccgata gtgggaagcc tcggcaaata actgatgata tcaacattaa acgaaccaat
     6541 aacgcatact tgacttttca tagttgagtg gccttttttt attccctggg ctgtatcata
     6601 attttcaagc gcataagcga tttcattttt cgcaatagta tcaagcgagt ctaggacgat
     6661 aaaagcaccg ccatgacatc gagtcagata gccaagcctg gcaagttcat taagatctga
     6721 tcgaatagtt tctttcgtta cattgaggct attggacaga tcggatactt ttacagaacc
     6781 gaatttactg agtcgtttca atatttcatg atggcgttca aatttcatgc ttcacctcac
     6841 ttcagttacg ttaatatcta tcgatgtata ttgatgtgat aatcaccata aagtggcggg
     6901 gaaaagcaaa aaaaagcaaa aatagcctga gaaaaggtaa gcgttaatgg agaatcatat
     6961 tgatgcttat ttattggtga gaactacgtt ccatggcagg agttcatcaa tacggttgga
     7021 aggttattcc ggcagtacgc tcaggatatg gcgcagatac gcttccggat caatgtcgtt
     7081 cagaaggcaa gtgccgataa gcccatacaa cagtgcactg cgctcgccgc cgaagaacat
     7141 aaagttttta tttccgagac agatggcaca aagggctttt tccgcggcat tatgtctgcc
     7201 tccgcctgac cgtcaacact gtaataacag agtgcgcccc actgattcag tacacagctg
     7261 aaccattcac ccagtctgga tttttggata gcgtggcatt tttctccacc atgcatgcag
     7321 tgagtccagt aacagtttgc tcttcttctg cctgaccaca agatgtgctg gactggtaaa
     7381 cgatggggat acctgcttac gcgagagcaa taagtggctg gccacaattc tcggtacaaa
     7441 actctgctga atagcagcga ttttcccagc gtggtgcgtc gtttgcattt tactggttct
     7501 aagttaacaa ttatctgttc actaatgact actctaaaaa cttgtatcag gactatcact
     7561 tatttaagtg atattggttg tctggagatt cagggggcct gtctagagag atataaagat
     7621 accttcaccc cggtgatgat aaaataaaag tatctcag
//
LOCUS       DAPOXO010000153         7562 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPOXO010000153 DAPOXO010000000
VERSION     DAPOXO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7562
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.153"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            121..1107
                     /locus_tag="ROH59_004788"
     CDS             121..1107
                     /locus_tag="ROH59_004788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDX4807174.1"
                     /translation="MSELIATAASSINAFTLAKRVAAFNVPVLIQGETGAGKECVAKY
                     IHTVAFGENDNAPYIGVNCAAIPENMLEATLFGYDKGAFTGAIASVPGKMELANNGTL
                     LLDEIGDMPLALQAKILRVLQEQQVERLGSNRQIKLNFRLIACTNKNLEQDVAAGRFR
                     EDLYYRLAVIPITMPPLRERLNDIIPLAESFIKKYATVLVKNITLSESTRRALLNYRW
                     PGNVRQLENAIQRGMILNRDGVIYPDALGLPETDIADHSELQWPVQPAVHIAETRDLG
                     QHGRSAQYQYIADLMRKYQGNRSKIADLLGITPRALRYRLASMRKQGIEVFS"
     gene            1122..1463
                     /locus_tag="ROH59_004789"
     CDS             1122..1463
                     /locus_tag="ROH59_004789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDX4807175.1"
                     /translation="MSITTINSTMQAQIMQDVQRMQANAQAPVLPSMTFSSTDPDVSF
                     NRIMYGALGHVDQFQQVAEQQQTAVDTGKSDDLAGAMIASQQASLSFSALVQVRNKIA
                     TGFNDLMSMSI"
     gene            1468..3114
                     /gene="fliF"
                     /locus_tag="ROH59_004790"
     CDS             1468..3114
                     /gene="fliF"
                     /locus_tag="ROH59_004790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001643010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDX4807176.1"
                     /translation="MNAQIKKLTQAFPAFRLHLVDNKRWVLMAGVGLAVAVTAIIVSV
                     LWTGNRGYVSLYGRQENLPVSQIVTVLDGEKLTYRIDPQSGQILVPEDALSKTRMTLA
                     AKGVQAILPSGYELMDKDEVLGSSQFVQNVRYKRSLEGELAQSIMSLDAVESARVHLA
                     LNEESSFVVSDEPQNSASVVVRLHYGAKLNMDQVNAIVHLVSGSIPGLQASKVSVVDQ
                     AGNLLTDGIGAGEAVSAATRKRDQILKDIQDKTRASVANVLDSLVGTGNYRVSVMPDL
                     DLSTIDETQEHYGDAPKINREESVLDSDTNQVAMGVPGSLSNRPPIAANQMTNGTEEN
                     RSPEALSKHSESKRDYSYDRSVQHIQHPGFAVKRLNVAVVLNQNAPALKNWKPEQTTQ
                     LTALLNNAAGIDAQRGDNLSLSLLNFVPQAVPVEPVIPLWKDDSVLAWVRLIGCGLLA
                     LLLLFFVVRPLMKRLTAVRAPVITPEPEAVSEPWIAMPEEERKNVDLPSLPGDDSLPS
                     QSSGLEVKLEFLQKLAMSDTDRVAEVLRQWITSNERIDNK"
     gene            3092..4102
                     /locus_tag="ROH59_004791"
     CDS             3092..4102
                     /locus_tag="ROH59_004791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDX4807177.1"
                     /translation="MSELTTNKSNSYLEQAAILLLCLGEEAAATVMQKLSREEVVRLS
                     ENMARLSGVKTSMARKVINHFFDEFREQSGINGASRSMLQGILNKALGTEIASSVING
                     IYGDEIRSRMARLQWVEPRQLAMLISEEHLQLQAVFLAFLTPEISAAVLSYLNESVQN
                     EILYRVAKLNDVNRDVVDELDRLIERGLSVLSEHGSKVKGIKQAADIVNRFQGNQQVI
                     LDQMRERDEEVLGQIQDEMYDFFILSRQNEEVRRRLLDEVPMEDWAVALKGTEALLRR
                     SIYAVMPKRQAQQLEAITARLGPVPVSRIEQIRREIMGIARELEEAGEIQLQLFAERT
                     AE"
     gene            4106..4816
                     /locus_tag="ROH59_004792"
     CDS             4106..4816
                     /locus_tag="ROH59_004792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein H"
                     /protein_id="HDX4807178.1"
                     /translation="MTIETLRGRYRLHRFPPRQRAVTGEPLTASISAADYQRQLMDGF
                     QEGLQKGFAQGMTEGQEQGFSEGHQQGFAEGRRQGYTEGSLAGQQEGRKQFVEAAQPL
                     EAITGKVNDFLAHIERKQREDLLQLVEKVTRQVIRCELALQPTQLLALVEEALAAFPT
                     MPETLQVMLSTEEFNRLRDAVPEKVSEWGLTPSPDLPPGECRVITDKSELDIGCEHRL
                     EQCMTALQETLTPESQGE"
     gene            4809..6149
                     /gene="fliI"
                     /locus_tag="ROH59_004793"
     CDS             4809..6149
                     /gene="fliI"
                     /locus_tag="ROH59_004793"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HDX4807179.1"
                     /translation="MSDFSAFDNALRSLESIPLARVAGRLVRLNGILLESVGCPLMTG
                     QLCRIESANHTLIDAQAVGFNRDITYLMPFKQPVGLMAGARVFPEEKAHDILIGESWL
                     GRVVNGLGEPLDGKGRLNGNDLLPPLPPSVNPLTRRSVDEPLDVGVKAINGLLTIGKG
                     QRVGLMAGSGVGKSVLLGMITRQTKADIVVVGLIGERGREVKEFIDHSLGADGLAKSI
                     VVVAPADESPLMRLKATELCHSIAAWFRDRGHHVLLLVDSLTRYAMAQREIALSLGEP
                     PATKGYPPSAFGMIPKLVESAGNSESSGSMTAIYTVLAEGDDQQDPIVDCARAVLDGH
                     IVLTRKLAEAGHYPAIDIGQSISRCMNQVTRLEHQQSARALKQNYAAYMEIKPLIPLG
                     GYVAGADASVDKAVKMFPAIERFLRQEMREPASLELVQSRLQILFPIAKKAEGQ"
     gene            6152..6586
                     /gene="fliJ"
                     /locus_tag="ROH59_004794"
     CDS             6152..6586
                     /gene="fliJ"
                     /locus_tag="ROH59_004794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HDX4807180.1"
                     /translation="MRQIIDTLAQLQRLRDKSVKDKTVELAKQKQICAGYDNNIKALG
                     YLVEKTSAGAAASVESLKNVSGYKGTLRKVIAWQEQEKTLANIKATRMQKNLTAAACE
                     EKVVALTLDDKRREQQESATAKAQKAVDDIAVQCWLRHKLAE"
     gene            6589..6984
                     /locus_tag="ROH59_004795"
     CDS             6589..6984
                     /locus_tag="ROH59_004795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HDX4807181.1"
                     /translation="MKTVITFGTFDVFHVGHLRLLQRARTLGEQLLVGVSSDALNIAK
                     KGRAPVYPQDDRMAIIAGLACVDGVFLEESLEQKAEYLRGYSADILVMGDDWAGKFDD
                     FSCVCEVVYFPRTPSVSTTGIIEVIRGHF"
     gene            complement(7004..7351)
                     /locus_tag="ROH59_004796"
     CDS             complement(7004..7351)
                     /locus_tag="ROH59_004796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000758621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807182.1"
                     /translation="MKKVYFVHRDKNAIERQSDGVEFCFIPEFNDGRIYFYCHEYDIF
                     WRSIKDAGDYAWCCNFHLKGIIRPATLIEISNSDLISYIDSIKEYEIENSKLININYI
                     HLNYDFLNIHQNT"
BASE COUNT         1852 a         1998 c         2154 g         1558 t
ORIGIN      
        1 ctaactagtt gtttataaac aaataatatt tttattatcg tttaattcga acttgttaat
       61 cccaccggtg atacgcttca gaacatcctg ttttctgtcg ctacttatat cgttcaccct
      121 atgtctgaac ttattgcaac tgccgcttcc agcattaacg cttttactct ggcaaagcgt
      181 gtcgccgcct ttaacgtacc ggtgctcatt cagggcgaaa ccggcgcggg gaaagagtgc
      241 gtggcgaaat atattcacac cgtagccttt ggtgaaaatg ataacgcgcc ctatatcggc
      301 gtgaactgtg cggcgatccc ggaaaatatg ctggaagcga ccttatttgg ctacgacaaa
      361 ggcgcattta ccggcgcaat tgccagcgtg ccaggaaaaa tggaactggc taataacggc
      421 accttattgc tcgatgaaat tggcgatatg ccgctggcat tacaggccaa aatattacgc
      481 gtattgcagg aacagcaggt tgagcgatta ggcagcaata gacaaatcaa actcaatttt
      541 cgcctgattg cctgcaccaa taaaaatctg gaacaggacg tggctgctgg acgttttcgt
      601 gaagatcttt attatcgtct ggcggttatt cctataacca tgccgccact gcgtgaacgt
      661 ctgaacgata ttattccgct ggcagagtcg tttattaaaa aatatgccac ggtgctggtg
      721 aaaaatatca ccctgtccga atccacacgc cgggcgctac ttaattaccg ctggcccgga
      781 aatgttcgcc aactggaaaa cgccattcag agaggaatga tcttaaaccg cgacggcgtg
      841 atttacccgg atgccttagg cctgccggaa actgacattg ccgaccacag cgaactgcaa
      901 tggcctgttc agcccgccgt ccacattgcc gaaacccgcg atttaggcca gcacggacga
      961 agtgcgcagt atcaatatat cgccgacctg atgcgtaaat atcagggcaa ccgcagcaaa
     1021 atcgccgacc tgttaggcat taccccgcgc gcactgcgct atcggctggc ctccatgcgc
     1081 aagcaaggta tcgaagtttt ctcctgaccc ggaagttaaa aatgagcatt accacaatca
     1141 acagcaccat gcaggcgcaa atcatgcagg acgtgcagcg gatgcaggcc aacgcccagg
     1201 cgccggtgct accctccatg accttcagtt ccacagaccc ggacgtgtcg tttaaccgca
     1261 ttatgtacgg cgcgcttggt cacgttgatc agttccagca ggtggcggag cagcagcaaa
     1321 cggctgtcga cacgggcaaa agtgatgacc tggcaggtgc gatgatcgcc agccagcagg
     1381 cgtcgctctc tttctccgcg ctggtgcagg tgcgcaataa aatcgccacc gggtttaacg
     1441 acctgatgag tatgtcgatc taaccctatg aatgcacaaa taaagaagtt aacccaggcg
     1501 tttccggcgt ttcgactgca tctcgtagat aacaaacgct gggtgttgat ggcgggagtg
     1561 gggcttgccg tggcggtgac ggcgattatc gtcagcgtgc tgtggaccgg taatcgcggc
     1621 tacgtttcgc tctacggacg ccaggaaaat ctgcccgtgt cgcagattgt cacggtgctg
     1681 gacggcgaaa agctcaccta ccgcatcgac ccgcagagcg ggcagattct ggtgccggaa
     1741 gatgcactgt cgaaaacgcg aatgaccctt gccgcgaaag gcgtgcaggc gatattgccc
     1801 agcggctacg agctgatgga taaagacgaa gtgctcggca gcagtcagtt cgtgcagaac
     1861 gtgcgctata aacgcagtct cgaaggggag ctggcgcaga gcatcatgtc gctggacgcg
     1921 gtggaaagcg cgcgggtgca tctggcgctc aacgaagaaa gctcgtttgt ggtcagcgat
     1981 gagccgcaaa acagcgcctc ggtggtggtg cgcttgcatt acggcgcgaa gctgaatatg
     2041 gaccaggtga acgccattgt gcatctggtg tccggcagta ttccggggct acaggccagc
     2101 aaagttagcg tcgtcgatca ggcgggaaat ctgctgaccg acggcattgg cgcaggcgag
     2161 gcggtttctg ccgcgacccg taaacgcgat cagatcctca aagatattca ggacaaaacc
     2221 cgtgccagcg tggcgaacgt gctggattcg ctggttggca cggggaatta ccgcgtcagt
     2281 gtgatgccgg atctcgacct cagcaccatc gacgaaaccc aggaacacta cggtgacgcg
     2341 ccgaaaatca accgcgaaga gagcgtgctg gacagcgaca ccaatcaggt ggcgatgggc
     2401 gtgcctggtt cgctcagtaa ccgtccgccg attgcagcga atcagatgac caacggtacg
     2461 gaagaaaacc gctcgccgga agcgctttcc aaacacagcg aaagtaagcg cgactactct
     2521 tacgaccgca gcgtccagca tattcagcat cccggcttcg cggtgaaacg cctcaacgtg
     2581 gcggtggtac tcaatcaaaa cgctccggcg ctgaaaaact ggaagccgga gcaaaccacg
     2641 caactgaccg cgttgctgaa caatgccgcc gggatcgacg cccagcgtgg tgacaatctc
     2701 tccttatcgt tactcaactt tgtaccgcag gcggtgcctg tcgaaccggt tattccactg
     2761 tggaaagatg acagcgtact ggcctgggtg cggctgattg gctgcggcct gctggcgctg
     2821 ttgctgctgt tcttcgtggt gcgtccgttg atgaaacggc tgacggcggt acgtgcgccg
     2881 gttatcacac cagaaccgga agccgtcagc gaaccgtgga ttgccatgcc ggaagaggag
     2941 cgcaaaaacg tcgacctgcc gtcgctgccc ggcgatgaca gcctgccgtc acaaagttct
     3001 ggcctcgaag tgaaactcga gttcctgcaa aaactggcca tgagcgacac cgatcgcgta
     3061 gccgaagttc tcagacaatg gatcaccagc aatgagcgaa ttgacaacaa ataagagcaa
     3121 cagctacctg gaacaggcgg cgatcctgct gctgtgtctg ggcgaagagg cagcggcgac
     3181 ggtgatgcaa aaactcagcc gcgaagaagt ggtgcgcctg agcgaaaaca tggcgcgact
     3241 ttccggcgtc aaaaccagca tggcgcgtaa agtgatcaac cacttctttg acgagttccg
     3301 cgaacagagc gggatcaacg gcgcatcgcg atccatgttg cagggcattc ttaacaaggc
     3361 gttgggtacc gagatcgcca gcagcgtgat caacggcatc tatggcgatg agattcgctc
     3421 gcggatggcg cgcctgcaat gggtggaacc acgccagttg gcgatgctga tttccgaaga
     3481 acatctgcaa ttgcaggcgg tgttcctcgc gtttctgacg ccggaaatct cggcagcggt
     3541 gctctcttat ctcaacgaat cggtgcaaaa cgaaattctc taccgggtgg cgaaactcaa
     3601 cgacgtcaac cgcgacgtgg tggatgagct ggaccgcctg attgaacgtg gcctgtcggt
     3661 actttcggaa catggctcga aggtaaaagg catcaaacag gcggcggata tcgtcaaccg
     3721 cttccagggc aatcagcagg tgatcctcga ccagatgcgc gaacgcgacg aagaggtgtt
     3781 ggggcagatc caggatgaga tgtacgactt ctttatcctc agccgccaga acgaagaagt
     3841 gcgtcggcgt ctgcttgatg aagtgccgat ggaagactgg gcggtggcgc tgaaaggcac
     3901 cgaagccctg ctgcgccgct cgatttacgc ggtaatgcca aaacgtcagg cgcagcaact
     3961 ggaagcgatc accgcgcgtc tgggtccggt gccggttagc cgtatcgaac agatccgccg
     4021 cgaaatcatg ggcatcgccc gtgagctgga agaagcgggc gaaattcagc tacagctctt
     4081 tgcggaacgg acggcggagt aattcatgac cattgaaaca ctgcgcgggc gctatcgcct
     4141 gcaccgcttc ccgccgcgcc agcgtgcggt gaccggagaa ccgcttactg ccagtatcag
     4201 cgccgccgat taccagcgtc agttgatgga cggttttcag gaagggctgc aaaaagggtt
     4261 tgctcaggga atgaccgaag gtcaggagca gggctttagc gaaggtcatc aacaaggttt
     4321 tgccgagggg cggcgtcagg gctacaccga aggcagcctc gccgggcagc aggaaggacg
     4381 caaacagttt gttgaggcgg cgcagccgct ggaagccatc accggtaaag tgaacgactt
     4441 cctcgcgcat attgaacgta aacagcggga agatttgctg caactggtgg agaaagtcac
     4501 ccgtcaggtg atccgctgcg aactggcgct gcaaccgacg cagttactgg cgctggtgga
     4561 agaggcgctg gcggccttcc cgacgatgcc ggagaccctg caagtgatgc tgagtacaga
     4621 agagtttaac cgcctgcgcg acgcggtgcc ggaaaaagtc agcgaatggg ggctgacgcc
     4681 ttcgccggat ctgccgccag gcgaatgccg ggtgattacc gacaaatctg aactggacat
     4741 cggctgtgag catcgccttg aacagtgcat gaccgcgctg caagagacgc taacgccgga
     4801 gtcgcagggt gagtgatttt tctgctttcg ataacgccct gcgctcgctg gagtcgatcc
     4861 cgctggcccg cgtcgccggg cggctggtgc gcctgaacgg cattctgctg gagagcgtcg
     4921 gctgcccgct aatgaccggg caactgtgcc gcatcgaaag cgccaatcac acactgatcg
     4981 acgcgcaggc agtgggcttt aatcgcgaca tcacctactt aatgccgttt aaacagccgg
     5041 tcggcctgat ggcaggcgca cgcgtcttcc cggaagaaaa agcccacgac atcctgattg
     5101 gcgaaagctg gttaggccgc gtggttaacg gtctcggcga accgctggat ggcaaaggcc
     5161 gcctgaacgg caacgacctt ctgccgccgc tgccaccctc ggtcaatccc ttaacccgcc
     5221 gttcagtgga cgaaccgctg gacgtgggcg tgaaagcgat taacggcctg ctgaccatcg
     5281 gcaaaggcca gcgtgtcggg ctgatggcgg gcagcggcgt cgggaaaagc gtgctgctgg
     5341 ggatgatcac ccgccagact aaagccgaca tcgtggtggt cgggttgatt ggtgaacgcg
     5401 ggcgcgaagt gaaagagttt atcgaccact cgctgggcgc agacgggcta gcaaagtcta
     5461 tcgtcgttgt cgcgcctgcc gatgaatcgc cgctgatgcg cctgaaagcc accgaactgt
     5521 gccactccat cgccgcctgg tttcgtgacc gcgggcatca cgttttactg ctggtggatt
     5581 ccctgacccg ctacgccatg gcgcagcgtg aaattgctct ctcactcggt gaaccacccg
     5641 ccaccaaagg ctatccacca tcggcattcg gcatgatccc caaactggtc gagagcgcag
     5701 gcaacagcga aagctcagga tcgatgaccg ccatctacac ggtgctggcg gaaggcgacg
     5761 accagcaaga tccaatagtc gactgcgccc gcgcagtgct ggacggacat atcgtattaa
     5821 cccgcaaact ggcggaagcg gggcactatc cggctattga tatcggccag tcgatcagcc
     5881 gctgcatgaa ccaggtcacc cgcctggaac atcagcaatc cgcccgcgcg ttaaagcaaa
     5941 actacgccgc ctatatggag atcaaaccgc tgatcccgct cggcggctac gtggcaggcg
     6001 cggacgccag cgtcgacaaa gcggtgaaaa tgttcccggc tatcgagcga tttttgcgcc
     6061 aggagatgcg cgaacccgcc tccctcgaac tggtgcaaag ccgcctgcaa atcctctttc
     6121 ccatcgccaa aaaggcagaa gggcaataac catgcgacaa atcatcgaca ccctggcgca
     6181 gttgcagcgc ctgcgggata aatcggtcaa agacaaaacc gtcgagctgg caaagcaaaa
     6241 acagatttgc gctggctatg ataacaatat caaagcatta ggttaccttg tcgagaaaac
     6301 atctgcgggc gcggcggcgt cggtggagtc gctgaaaaac gtcagcggct acaaaggcac
     6361 actgcgcaag gtgatcgcct ggcaagagca ggaaaaaacg ctggccaaca tcaaagctac
     6421 gcgaatgcag aaaaacctga cggcggcggc gtgcgaagag aaagtggtag ccctgacgct
     6481 ggacgacaaa cgccgcgagc aacaggaaag cgccacggcg aaagcgcaaa aagcggtgga
     6541 tgacatcgcc gtccagtgct ggttgcggca caaattagcg gagtagccat gaaaacggtc
     6601 atcaccttcg gcaccttcga tgtgtttcat gtgggtcatc tgcgcctttt acaacgcgct
     6661 cgcacgctgg gcgagcagct gctggtcggc gtatcatccg atgccttaaa tatcgccaaa
     6721 aagggcaggg ctccggttta ccctcaggat gaccgcatgg cgattatcgc cgggctggcg
     6781 tgcgtggatg gcgtatttct ggaggagtcg ctggagcaga aagcggaata tttgcgcggg
     6841 tacagtgcgg atattttggt gatgggcgat gactgggcag gtaagtttga cgatttctcg
     6901 tgtgtatgtg aggtggtcta ctttccccgc acgccgtcgg tatcgacgac ggggatcatt
     6961 gaggtgatta gggggcattt ctgataatat gagttcctct attttaggta ttttgatgaa
     7021 tatttaaaaa atcataattc aaatgaatat agttaatgtt tatgagttta ctgttctcta
     7081 tttcatattc tttaatagag tcaatataag atattaaatc ggaatttgat atctcaataa
     7141 gagttgccgg acgtataatt ccctttagat ggaaattaca gcaccaggca tagtcaccag
     7201 catccttgat tgaacgccaa aatatatcat attcatgaca atagaaataa attcttccgt
     7261 cattgaactc agggatgaaa caaaattcta caccgtcact ttgacgttca attgcattct
     7321 tatcacgatg aacaaaataa acttttttca tatgaatatt tcctgtcgtt tttgttaata
     7381 aatacgctga gatcgaatgt atactaacaa taatattgat ggatgtctta agtttaattt
     7441 attccgtaag tgtttgtcgg aagtttattt ttaattgatg tcgtgcacac aaagaaacaa
     7501 attcatcgct gacgatgaca atatgattca ttaagacatt ctcttctctg gctattagaa
     7561 at
//
LOCUS       DAPOXO010000154         7223 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPOXO010000154 DAPOXO010000000
VERSION     DAPOXO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7223
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.154"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(1..539)
                     /gene="papA"
                     /locus_tag="ROH59_004797"
                     /pseudo
     CDS             complement(1..539)
                     /gene="papA"
                     /locus_tag="ROH59_004797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_151035091.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="P fimbria major subunit PapA"
     gene            complement(747..1060)
                     /locus_tag="ROH59_004798"
                     /pseudo
     CDS             complement(747..1060)
                     /locus_tag="ROH59_004798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin biosynthesis transcription regulatory
                     family protein"
     gene            1465..1698
                     /gene="papI"
                     /locus_tag="ROH59_004799"
     CDS             1465..1698
                     /gene="papI"
                     /locus_tag="ROH59_004799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major pilus subunit operon transcriptional
                     regulator PapI"
                     /protein_id="HDX4807183.1"
                     /translation="MSEYMKNEILEFLNRHNGGKTAEIAEALAVTDYQARYYLLLLEK
                     EGVVQRSPLRRGMATYWLLKGEKQAGQNCSSTT"
     gene            complement(2262..3475)
                     /locus_tag="ROH59_004800"
                     /pseudo
     CDS             complement(2262..3475)
                     /locus_tag="ROH59_004800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558238.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     misc_feature    complement(3078..3194)
                     /locus_tag="ROH59_004800"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /pseudo
                     /db_xref="RFAM:RF01497"
     gene            complement(3566..3679)
                     /locus_tag="ROH59_004801"
     CDS             complement(3566..3679)
                     /locus_tag="ROH59_004801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HDX4807184.1"
                     /translation="MKMKHLRDDVAAGRRRLYIRAICPSLREAPLLYSYPL"
     gene            complement(4215..4964)
                     /locus_tag="ROH59_004802"
                     /pseudo
     CDS             complement(4215..4964)
                     /locus_tag="ROH59_004802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343760.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            5513..5773
                     /locus_tag="ROH59_004803"
     CDS             5513..5773
                     /locus_tag="ROH59_004803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX4807185.1"
                     /translation="MNYVICTTIVALGLILTGYATAADEINRQDVVGLMPSDYISVGN
                     LYTPEEVATALKDKAEQAGGSHFRITSLGGKNKLDGTAIIYR"
     gene            5815..6375
                     /locus_tag="ROH59_004804"
     CDS             5815..6375
                     /locus_tag="ROH59_004804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000109148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX4807186.1"
                     /translation="MSTYENILRITDTLIQQRGFLGFSYADLEKEIGIRKASIHHHFP
                     RKTDLGIAYCQYKTEVFDRLNITLHNVSSGVQRLRTYLDAFAGCAERGEMCGIYAMLS
                     DSHQFSPELQEAVSQLAHQEIQMIKDIITSGQNSGEFKTVLLPDELAVIVCSTLKGAL
                     MLNRLPPHDIYSGTVNALIKMLDTRT"
     gene            6415..6843
                     /locus_tag="ROH59_004805"
     CDS             6415..6843
                     /locus_tag="ROH59_004805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF417 family protein"
                     /protein_id="HDX4807187.1"
                     /translation="MKKFINVYIKSDYDIVILRLSVIIIFMLFGTYKWFDFEVMALKP
                     LISPTWLNILYIMFGVHGGSYFLGIVETITFLALSIGFFRPAAGILGDIIVIVTGLVT
                     LSLLPQLGKVDSFVIKDVLLLGAGSVLLKYDLKNYLNIKN"
     gene            complement(6986..7199)
                     /locus_tag="ROH59_004806"
                     /pseudo
     CDS             complement(6986..7199)
                     /locus_tag="ROH59_004806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
BASE COUNT         1995 a         1763 c         1461 g         2004 t
ORIGIN      
        1 tgcgactgca gaaaaagcac cctcagtgac ttgggcatta ttggctgacg acttcttaac
       61 aatcgcagta taatgcagca cattatcacc atctttcagg gtattagcat caccttctgt
      121 gccatcgaaa gaaacgtttt tacctgcagc ctgaactaca atcgcagtac ctgtcccccc
      181 gctggtatct aactcctcat tatgaccaga aacccttgga ccactaaaag ccagcttcac
      241 agtccctttt tttgctgccg agactcctcc ccccccttaa atgaagtgat atcacaatta
      301 accaattcaa tatctaaatt cattggtttg gatacgcctc ctgcttgaag gaagcttttt
      361 gaaagctgtc caaaatcaat agactgatca gctgatttct gagaaatgct gcatggagca
      421 tcaacaacag ttccgttaaa ggttactcta ccctgcccct gtggagtagt tagagcagca
      481 tttacaccaa aagacaccac tgccatagct accgcaccgg caataaccga cttaatcata
      541 aataacaacc tctttttcat tactgaacac accagagata tctggcaatt taaaatgacc
      601 cgattacctt taataaccag atcaatacaa ataatattct cgtattttca gggcaggtta
      661 tttatcgaca gaatactgat ataacctgtc tgctttctga caagggcttc tttttttatc
      721 ttccagaaac tccggaatgc cataatttag tcaaatgccg atgactcatc tgtataataa
      781 ggtgcaagcc ttgctgcaag agcattcagc cgtataagtc tccccagtgt tgtactgaaa
      841 tacccattat tcatctggta tttctcgcag acctccttac gggagtgccc acctaccaga
      901 tagtccttca tagccagaat gaccctgtca ctgtgaatag aagaaatacc tatcagtaaa
      961 aaaaatgcat ttcagacata gagccgagca acagcacgct ctcgcgtata ttcagcaaaa
     1021 acgcatttcc tgaccgactg atgacttcat gatgcgccat gtttccccct tctgtcgggc
     1081 ccctggatat atgcttccgg cccggaaata ctcttcacgc aataagttaa atttagtttt
     1141 ttatgttgta aatattgatt taaacgatct tttaacccac aaaacaaaat taaaccagaa
     1201 taaaattcta acaacaagaa tacactcaga taaaaacatc atggtgaatt gaatttacag
     1261 cataaaagat cgtctaaatg catttttacg gactttcttt tcacagaaaa ataacacaca
     1321 aaatgtgata cacatcaaat aaagccaaca aaaagcaaat tcactaaatt gcacaaataa
     1381 agcaaacaca gagaataaaa atacctttcc gttgataaca gagagcatga tttttattat
     1441 tcgaagaaac tttgttacag tgagatgagt gaatatatga agaatgaaat actggaattt
     1501 ctgaacaggc ataatggagg gaaaaccgca gaaattgcgg aggcgctggc ggtaacggat
     1561 tatcaggcac gctattacct gttattactg gaaaaagaag gtgtggttca gcgctctcca
     1621 ttaaggcgag gcatggcaac atactggctt ctgaaaggag agaagcaggc ggggcagaac
     1681 tgttcttcca caacttaata actcaatctg tgggcatgct tcactgaaac agataaaagt
     1741 tacatcagag tgcagattca gttttgcagc attcatcaca aaatagaaat ttagtatttt
     1801 atgtcagaat acttcacatg ataataaaaa cctgtctgga tttactgcat ggccagacat
     1861 tacaaaatac aaacgccata aacttcattc agccttcttg ctgtccggta acggaggctg
     1921 ctttttcgtt acacctttcc ccggcagcat cagtagcagt aatttataga ttctacgaac
     1981 tgagactgtc tgtccgggga gaacgtacac agcccgacac aatgtaccag tcaataatat
     2041 ccggtttctg attccctgcc tgacagacca ctctctggca actttgtatt cagttcatct
     2101 actactggag acagatttat aaaatccaac tccacgatct ttgaccgtcc gcatccccta
     2161 ctctctgtgc tgcggtcatc ggttaattcc agcgtccgtc cgttacgatc agatattact
     2221 gaaccgcccc gggtttcctg gagagtgttt tatctgtgaa ctcaggctgc cagatcattg
     2281 tttccgatgg aagcataata agctttttct gcttctgccg gaggagtatg gcccagcctt
     2341 cccagcaatc atcgattgtt ataccagtcc acccacgtga gtgtggccag ttccacttct
     2401 gcacggtttt tccagctctt acggtgtatt acctccgctt tgtaaagacc attgatgctc
     2461 tccgccatcg cgttgtcata cgagtcgcct gtactccctg ttgatgccag cagttttgct
     2521 tcttttaatc gctccatata ggccagtgac acatactgag agcctttatc gctgtgatgg
     2581 atggtgccgg acggacggcg ggcccacaac gcctgctcca gcgcatccag cacgaatgtc
     2641 gtttccatag acgatgagac ccaccacccc acgatgtatc cggcaaacac atcaatgatg
     2701 aacgccacat agacgaagcc ctgccatgtg ctgacgtaag taaaatcagc cacccacagc
     2761 tggtcaggac gttctgccac gaactgacgg tttacgcggt cacctgcagc aacggttttc
     2821 cggctgacgg tagtgcggac ctttttaccc cggagaacac cggcaagtcc cataaccgcc
     2881 atgaggcgcg ccactgtaca tctggccacc ctgattcctt cccgtaacaa ctgacgccag
     2941 actttacgca caccgtacac ctgatgattt tcatcgtata cgcgctgtat ctctctcttc
     3001 agccagtcat cgcgctgaca acgggcactg cgtttatcag gatgatgccg ctgctgctga
     3061 caatggtaat acgttgacgg ggcaatatgc tgttcactgc ataccggtcc gaccccgtac
     3121 tgctcacgca gcttatccag cagtggcatt attttttcca gaggcggtcg aactccgcct
     3181 tcgcaaaata agcggaagcc tggcgaagga tatcgttact gcggcgcagt tcacgatttt
     3241 cacgttccag ctctttcaga cgctgacgtt cagcggtggt gagcccacca tcaccgcccc
     3301 cggtatcccg ctcatgctgg cgaacccaga cacgcagagt ctctggcgta cagccaatct
     3361 ttggagctat ggaacaaatt gccgcccatt gtgagtcata ttcgtcctga ctttccagaa
     3421 ccatacgaac tgcccgttga cggacttcgg gggaaaaacg tgtattttta gtcatcctgt
     3481 ttacctcttt ctcagggaat ttagtctcca ggattcccgg ggcggttcac agtaatcatg
     3541 ccgggtctgg ctggctaaca ccccattata aggggtacga ataaagtaac ggggcttcac
     3601 gcagggatgg acagattgct ctgatataca gccgacgacg tcccgctgca acatcatcac
     3661 gcagatgctt cattttcaga tttgggacct ccttttgatt tctcgtttaa cttttgctgt
     3721 taccagactt taatctattt taacaattca agaatttttt ataaaatgct caaagatgaa
     3781 agcgttactg aaccaaccag cttggctgat gttttctata gataaaaaga tcatcagcaa
     3841 aaactgatag cctgaatcac ctttactacc aatcatgtat gaagaaaaca cgcacaaaca
     3901 attgacaatg attatcattt gcattaaaag gattatgtag tatttttatt tcatgaggaa
     3961 ctatacccgc cagcaatctg agtagcgaaa gctgttcatc cccaatattt ttgctggcgg
     4021 gttctttttt ctactgccct tctcctcaga gggagcattc cattcttttt ttcattaatg
     4081 gcgagggggc gggacaaaaa gccggttctt tatccctaaa taacagcatg atttcagtcc
     4141 atgcaaaatc tgatttacca gctcacataa taacctgatg atacatgggt tttccctgat
     4201 catggtggga aggctcagaa cgccatattc agtttcccgt agtggaacat cacgcccagc
     4261 ttaaagcgct cccgatttcg gtatcccctg gcttttatcc tcagtagcct gatcttactg
     4321 ttaagcgcct ccgcgtttcc gtttgagaca cggtgtcgca tggcattcag gatcccgtaa
     4381 agcctttttc ctatcgtttt cgcggcgttt ttcatcatag gaacgtcact gttggccgcc
     4441 agagccagcc atctctccca gtcattacgt ctttcctcac tccatggcct gttccagata
     4501 tcctttgcca gctctttcag cgcccagcac tggcttgtca gcttcatctg tgcacgcagc
     4561 catatcagct tttcctgcct ggatttggtc atccatttat cgctgtactg ccacaggaag
     4621 cgggtcccct ttgcctgacg ccaactttca acagggaggt gcggatgttc attctgacgg
     4681 gttttatcaa ccacttcgcc aagttgcttt gctacatgga agcggtcgaa ggcgattttc
     4741 tcaaccgcac agggtaagtg gatacgcgct gctcttatat agcctgcatt catgtccatt
     4801 gagagcgttt tgatagccag caactgcccg tcagtaagcg tgcgaagata gccggcgagg
     4861 ctctctgtgc cacgatcgtc cgttaaggcc agcgcacgac catcgcgatc ggagatcacc
     4921 gttatataac gatgtccttt tttaaaggcg acctcatcca cattgtcagc accagtgata
     4981 taagacggat agcaaagcgc acgcgctgtt tgtcaccgtg aaaaacgacg gtgcgacggc
     5041 aaaagccaat aacaacgaga gcgtcgtgcg cattcctctg cactgacagt tgattcttag
     5101 aacgtagagg cctggattgc tgccaggctt ttattgcact accagctacg gctaaaagat
     5161 aagcgtcccg ggaagtacat agcgcttaca aaatatccga catgaagcat actggaaacg
     5221 aggcgtattg ttattgttgt tcatattggc ttccgtggcg gaaatatcag ggggtagcta
     5281 catatccccc atgcagccaa ggcaacgatg ttaactctcg tcacctgttc ctttcgacag
     5341 agccaacctc gcagagggcc agatcttaca acttcacctc agtgatacaa aacacaaaaa
     5401 tacaaaacaa tttgatacaa atcatccctc ttattttaaa taaatccatc ttgcaagcct
     5461 accaatcaga aggtagcatg tgtagtatcg caaacataaa gagaaattgc tcatgaatta
     5521 tgttatctgc actaccattg tcgcccttgg tctcattctg acaggctacg caactgctgc
     5581 agatgaaatt aatcgtcagg acgttgttgg tttgatgccg tcagactata tttctgttgg
     5641 taatctatat acaccagaag aggtggcaac tgcgcttaaa gacaaagcgg agcaggcagg
     5701 aggttctcat ttccgaatca cttcattggg aggaaaaaat aaacttgatg gaactgccat
     5761 tatctatcgc taaaatatgt ataatagtcc ctttaataca taacaggtaa agccgtgtct
     5821 acttatgaga atatacttcg cataacggat actctgatcc agcaacgcgg atttttgggg
     5881 ttcagttacg cagatctgga aaaagaaatt ggtatcagaa aagccagtat tcatcaccat
     5941 ttcccgagga aaactgatct tggtatagcc tactgccaat acaaaacaga agtatttgat
     6001 agacttaata taactctcca taatgtttct tcaggtgtac aacgtctcag gacatatctt
     6061 gatgcatttg ctggttgtgc tgaaagaggg gaaatgtgcg gtatttatgc catgctatcc
     6121 gacagccatc agttttctcc tgaattacag gaggctgtaa gtcaactggc acatcaggag
     6181 atacagatga ttaaagatat tatcacctcc gggcagaata gtggagagtt caaaacagtt
     6241 cttcttccgg atgagctcgc cgttatagtc tgttctacac taaagggggc actgatgtta
     6301 aatcgacttc caccacatga tatctattca ggaaccgtta acgctttaat taaaatgctt
     6361 gatacccgta cttaatcctt tttagtgcat ataattttcc acccggagaa tgaaatgaaa
     6421 aaatttatta atgtttacat taaatcagat tatgacatag ttattcttcg cctgtctgtt
     6481 attataatat ttatgctctt cgggacctat aaatggtttg attttgaagt gatggccctc
     6541 aagcccctga tttctcccac gtggctgaat atcctgtaca ttatgtttgg tgttcatggg
     6601 gggagctatt tcctcggcat agtagaaact atcacttttc tagcactgag tatcggcttc
     6661 ttcaggcctg ctgctggcat actgggagat attatcgtta ttgttacagg tttagtcaca
     6721 ctaagtctgt taccacaact gggaaaagtt gacagttttg tcatcaaaga tgtgctgctg
     6781 ttaggtgctg gtagtgtcct gctgaaatat gatttgaaaa attatttaaa tatcaaaaac
     6841 tgatttttca cttcggtgat gaacgtttgc gtattttcat ggaaagagat tacctaatcc
     6901 ccctcgttct ccttcatgtt aatacgcaac gttatggaaa acaaaaatac cctgagtaaa
     6961 aaggtccgta ggcaggcgag tacttttatt ttccgctagt tttactttcc catcgaaggc
     7021 cccatacatc actacgccca cgaaacaacc gacgaaataa cgcaactttc tcatccgtgg
     7081 ataatacgga aacgcactgc acaggactct gcggtttacg tcgccattca atcccataag
     7141 cttcaagtga tgtcttccct cagtgctgct aattcatcac tgtcagattt atgaaccata
     7201 ttcgttacct gtatccgaac cac
//
LOCUS       DAPOXO010000155         7040 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPOXO010000155 DAPOXO010000000
VERSION     DAPOXO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.155"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            192..1442
                     /gene="frc"
                     /locus_tag="ROH59_004807"
     CDS             192..1442
                     /gene="frc"
                     /locus_tag="ROH59_004807"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HDX4807188.1"
                     /translation="MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDV
                     TRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAI
                     DHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
                     LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRL
                     DKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQN
                     WENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIP
                     CAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEH
                     TAAVLQELGYSDDEIAAMKQNHAI"
     gene            1496..3190
                     /gene="oxc"
                     /locus_tag="ROH59_004808"
     CDS             1496..3190
                     /gene="oxc"
                     /locus_tag="ROH59_004808"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HDX4807189.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIIL
                     GKGAAYSQSDEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            3260..4204
                     /gene="yfdV"
                     /locus_tag="ROH59_004809"
     CDS             3260..4204
                     /gene="yfdV"
                     /locus_tag="ROH59_004809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HDX4807190.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            4278..5423
                     /gene="yfdE"
                     /locus_tag="ROH59_004810"
     CDS             4278..5423
                     /gene="yfdE"
                     /locus_tag="ROH59_004810"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HDX4807191.1"
                     /translation="MTNNECKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPR
                     FSSNILRVHNQAILKEYIERTLKTQVAEVWLARIHEVGVPVAPLLSVAEAINLPQTQA
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(5479..>7040)
                     /gene="evgS"
                     /locus_tag="ROH59_004811"
     CDS             complement(5479..>7040)
                     /gene="evgS"
                     /locus_tag="ROH59_004811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HDX4807192.1"
                     /translation="AVYICGWQDITETRDLIHALEVERNKAINATVAKSQFLATMSHE
                     IRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQ
                     LQPQWVDIPTLVQNTCHSFAAIAASKSIALSCSSTLPERYLVKIDPQAFKQVLSNLLS
                     NALKFTTEGAVKITTSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQ
                     QTGSGLGLMICKELIKNMQGDLSLESHPGIGTIFTITIPVEITQQVAAVEAKAEQPIT
                     LPEKLSILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKISMQHYDLLITDVNM
                     PNMDGFELTRKLREQNSSLPIWGLTANAQANEREKGLNCGMNLCLFKPLTLDVLKTHL
                     SQLHQVAHIAPQYRHLDIEALKNNTANDLQLMQEILMTFQHETHKDLPAAFHALEAGD
                     NRTFHQCIHRIHGAANILNLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELD
                     QEITVFCQQND"
BASE COUNT         1850 a         1488 c         1676 g         2026 t
ORIGIN      
        1 tcttttcgtc ctcactactt accatgcaga aaggaattgg aagtagcgat gaaatgattt
       61 tcagcacttg atacaggaat ttaaaaatat cgagtgcagc tacgacgata ttttgcagat
      121 tatttataga ggcgttatgc cttaaataaa cgctaaatta acacatattt aattaactaa
      181 taggtattgc tatgtcaact ccacttcaag gaattaaagt tctcgatttc accggtgtgc
      241 aatctggccc atcttgtact caaatgctgg cctggtttgg cgctgacgtc attaaaattg
      301 aacgtcccgg cgttggtgac gtaacgcgcc accagctgcg agatattcct gatatcgatg
      361 cgctttactt caccatgctt aacagtaaca aacgttctat tgaattaaat accaaaacag
      421 cggaaggcaa agaggtaatg gaaaagctga tccgcgaagc tgatatctta gtcgagaact
      481 ttcatccagg ggccattgat catatgggct tcacctggga gcatattcaa gaaatcaatc
      541 cacgtctgat ttttggttcg atcaaagggt ttgatgagtg ttcgccttat gtgaatgtaa
      601 aagcctatga aaacgttgct caggcagcgg gtggcgcggc atctactaca ggtttttggg
      661 acggtccgcc gctggtaagc gctgcagcgt tgggtgacag caacaccgga atgcatttgc
      721 tgatcggttt acttgctgct ttgctgcatc gcgaaaaaac ggggcgtggg caacgagtga
      781 ccatgtcaat gcaggatgcc gtgttgaacc tttgccgcgt gaaattacgc gaccagcagc
      841 gtctcgataa attgggttat ctggaagaat acccgcagta tccgaatggc acatttggtg
      901 atgcagttcc ccgcggtggt aatgcgggtg gtggtggtca gcctggctgg atcctgaaat
      961 gtaaaggctg ggaaaccgat cctaacgcct atatttattt cactattcag gagcaaaact
     1021 gggaaaacac ctgtaaagcc atcggcaaac cagaatggat taccgatccg gcatacagta
     1081 cagcccatgc ccgacagcca catattttcg atatttttgc tgaaatcgaa aaatacactg
     1141 tcactattga taaacatgaa gctgtggcct atttgactca gtttgatatt ccttgcgcac
     1201 cggttttaag tatgaaagaa atttcacttg atccctcttt gcgccaaagt ggcagtgttg
     1261 tcgaagtgga acaaccgttg cgtggaaaat atctgacagt tggttgtcca atgaaattct
     1321 ctgcctttac gccggatatt aaagctgcgc cgctattagg tgaacatacc gctgctgtat
     1381 tgcaggagct gggttatagc gacgatgaaa ttgctgcaat gaagcaaaac cacgccatct
     1441 gatattaacg ggggcttctg gctcccaatt tataaaaatt tcgaggttat taatcatgtc
     1501 agatcaactt caaatgacag atggtatgca tatcatcgtt gaagcattaa aacagaataa
     1561 tattgacact atttatggtg ttgtaggtat tcctgtgacg gatatggcgc gccatgccca
     1621 ggcggaaggc attcgttata ttggttttcg tcatgagcag tcggcaggtt atgccgctgc
     1681 agcaagcggt tttcttaccc aaaaaccagg gatctgcctg acagtgtctg cgccaggatt
     1741 cctcaacggt ttgaccgcat tggccaatgc aacggtaaat ggttttccga tgatcatgat
     1801 tagcggctcc agcgaccgcg cgatcgtcga tctccagcaa ggtgattatg aagagctgga
     1861 ccaaatgaat gcggcaaaac cgtatgccaa agcagcattt cgcgttaatc agccgcagga
     1921 tcttggcatt gcattggcac gcgctatccg ggtctcagta tcgggtcgtc ctggcggtgt
     1981 ttatcttgat ttgccagcaa atgtcctggc cgcgacgatg gaaaaagacg aagcgttaac
     2041 cacgattgtt aaagttgaaa atccgtcgcc agcattattg ccatgcccga agtcagtcac
     2101 tagcgcaatt tcgcttttag caaaagctga acgaccatta attattcttg gcaaaggcgc
     2161 ggcgtattca caatctgatg aacagcttcg tgaatttatt gaaagtgccc agattccatt
     2221 cctgccaatg tctatggcga aagggatcct cgaagatacg catccactct ctgcggcagc
     2281 tgcgcgttcg tttgccctgg caaatgctga cgttgtcatg cttgttggtg cacgactgaa
     2341 ttggttactg gcacacggta aaaaaggatg ggcggcagat acacagttta ttcaactgga
     2401 tattgaaccg caggaaattg acagcaaccg ccccattgct gtgccagtcg ttggcgatat
     2461 tgcatccagt atgcaaggta tgctggcaga attgaaacaa aacacattta cgactccact
     2521 ggtgtggcgt gatattttaa atatccacaa gcagcaaaat gcacaaaaaa tgcatgaaaa
     2581 gttaagtaca gatacccaac cattaaatta ctttaatgca ttgagtgccg tgcgcgatgt
     2641 tttgcgcgag aaccaggata tttatttagt taatgaaggg gcaaataccc tggataatgc
     2701 acgaaatatt attgatatgt ataaaccacg tcgtcgtctg gattgtggca cctggggtgt
     2761 catgggcatc ggtatgggct atgccatcgg tgctagcgtg acctctggtt ctccggttgt
     2821 cgctattgaa ggtgatagtg cttttggttt cagtgggatg gagattgaaa cgatttgtcg
     2881 atataacctg ccggtgacga tcgttatttt taataatggc ggcatctaca gaggagacgg
     2941 tgttgacctc agcggcgctg gtgcaccatc gccaacggat ctgttgcacc atgcaaggta
     3001 tgacaaatta atggatgcgt ttcgtggcgt tggctataac gtcaccacga cagatgaact
     3061 tcgtcatgct ttaaccaccg gaattcagtc gcgcaaaccg accattatta atgtggtcat
     3121 cgacccagca gcaggaactg aaagtggcca tattaccaaa cttaacccaa aacaagtcgc
     3181 tggtaattaa atactgacat cgtctcctct tgccaactta ttatgcgatg gtgaggggac
     3241 ccttatcgga aatactatta tgctaacatt ttttattggc gatttattgc ctattatcgt
     3301 aatcatgctg ttgggttatt ttagcggcag acgagaaact ttttcagaag atcaagcccg
     3361 ggcatttaat aaactggtat taaactacgc tcttcctgcg gctctatttg tttctattac
     3421 cagggcaaac agggaaatga tttttgcgga cactcgcctg acccttgtat cacttgtggt
     3481 tattgtcgga tgtttctttt tctcctggtt cggttgctac aaatttttta aacgtaccca
     3541 tgcagaagca gcagtatgtg cattaattgc aggttcacct accattggat tcctggggtt
     3601 tgcagttctc gatcctattt atggtgattc cgtatcaaca ggtttagtgg tagcaattat
     3661 ttctattatt gttaacgcaa ttactattcc tattggtctg tatttgctga atccttcctc
     3721 aggagcggat ggtaagaaga atagtaatct gagcgcatta atttctgcgg caaaggagcc
     3781 agtagtatgg gcacctgttc tggcaacgat cctggtgctg gttggggtaa aaattccggc
     3841 agcatgggac ccaaccttta atctgattgc gaaggctaac tcaggggtag cggtattcgc
     3901 tgcggggttg actctggctg cacataaatt cgagttcagt gccgaaattg cttataacac
     3961 tttcctgaag ctgattctga tgccactggc gctgcttctc gtcggtatgg catgtcattt
     4021 gaatagcgaa catttgcaga tgatggtact ggcaggcgca ttaccgccgg cattctccgg
     4081 aatcattatt gccagccggt ttaatgtcta cacccgtact ggtacagcgt cattggctgt
     4141 gagcgtactg ggttttgtcg tcacggctcc tttgtggatt tatgtcagtc gactggtttc
     4201 ataatttatc atgttattga ttttacataa atgccgaagt gtcttttcac cttcggcttt
     4261 tttcaaggca taagcaaatg acaaataatg aatgcaaagg gccgtttgaa ggcttattag
     4321 ttatcgatat gacgcatgtc cttaatgggc ctttcggaac tcaacttctt tgtaatatgg
     4381 gcgcaagggt aattaaagtt gagccaccgg gtcatggtga tgatacccgc acatttggtc
     4441 cctatgtgga tggacagtca ctctattaca gttttattaa tcatggcaaa gagagtgtgg
     4501 ttcttgattt aaagaatgat cacgataaaa gtatatttat aaatatgctt aaacaagctg
     4561 atgtattagc tgagaatttt cgcccaggta caatggaaaa actcgggttt tcatgggaaa
     4621 ggttacaaga aatcaacccg cgccttatat atgcttcatc gtcaggtttc ggacataccg
     4681 gtccgctaaa agatgctcct gcctacgata ccatcattca ggcaatgagc gggataatga
     4741 tggaaacagg ataccctgat gctccgccag tgcgcgttgg tacctctctt gcggatctct
     4801 gtggcggtgt ttatttattc agtggaatag tgagtgcact ttatggccgc gaaaagagcc
     4861 agagaggggc gcatgtcgat atagcgatgt ttgatgccac tctgagtttt ctggagcatg
     4921 gactgatggc atatatcgcg actgggaagt caccacaacg cctgggaaat cgccatccct
     4981 acatggcacc ttttgatgtt ttcgatactc aggataagcc gattacgatt tgttgtggta
     5041 atgacaagct tttttctgcg ttatgccagg cactggagct tacggaactg gttaatgatc
     5101 cccgatttag cagcaatatt ttacgcgtac ataaccaggc tattcttaaa gaatatattg
     5161 agcggacgtt aaaaacgcag gtagctgaag tttggttagc cagaatacat gaagttggtg
     5221 tgcccgtcgc gccgttatta agtgtggctg aggccattaa tttaccacaa actcaggcga
     5281 gaaatatgtt gattgaagcc gggggaataa tgatgccggg taatccgata aaaatcagcg
     5341 gctgcgcgga cccgcatgtt atgccgggag cggcaacgct cgaccagcat ggggaacaaa
     5401 ttcgccagga gttctcatca taaatgtaag atgtgctggt aaatagctcc cacatttgaa
     5461 cattgtggga gccgctattt agtcattttg ctgacagaaa acagtaatct cctggtccag
     5521 ctctgcaatg tgttctttta cagagttcag caactgaaga atttcaggct tactgtcatc
     5581 tgaaacaggt gttatttcta actggtggct aatattaatc aacttttgca aattcaggat
     5641 gttagccgca ccgtggatgc gatgaataca ctgatggaaa gttctgttat cgccagcttc
     5701 tagtgcatga aacgcagcgg gtagatcttt atgcgtttca tgctggaaag tcatgagaat
     5761 ctcctgcatc agttgtagat cattcgccgt attattcttc agggcctcga tatcaaggtg
     5821 gcgatactga ggtgcaatat gcgcaacctg gtgtaactga cttaaatgtg ttttcagtac
     5881 atccagagtc aacggtttga acaaacataa gttcatgccg caatttaacc ctttttcacg
     5941 ttcgttagcc tgtgcgttgg ctgtaagccc ccagatgggt aaggaagaat tttgctcacg
     6001 gagtttgcga gtcaactcaa aaccatccat attcggcata ttaacgtcag taataagcag
     6061 atcataatgt tgcatactga ttttgtgtag cgcttgcaca ccatcagtgg cttcatcaac
     6121 atcatatcct aatagattta gctggcgttt gagtaatagc ctgttggtcg gatgatcatc
     6181 cgcgattaat atgctcaact tttcaggtag tgttataggt tgttctgctt ttgcctcgac
     6241 agccgccact tgttgggtaa tttctaccgg gattgtgatc gtaaatatcg ttcctatgcc
     6301 tggatgactt tctaatgaca aatcgccctg catgttttta attaattctt tgcagatcat
     6361 taagcctaaa ccagaacctg tttgctgacg acctgcactt gtttggctat agcgtttaaa
     6421 cagttgttgt tgttcttcct gcgataatcc acttccagaa tccataatcg tcattttgat
     6481 aacagcgtgg ttgtcatcaa tgtgacccag ggaggtcgta atttttactg ccccctcggt
     6541 agtaaatttg agagcattac tcagtaaatt agataagacc tgcttaaacg cctgagggtc
     6601 gatcttaacc aggtagcgtt caggaagcgt actgctgcaa cttaatgcga tcgatttgct
     6661 tgcagcaatc gcagcgaaag agtgacaagt gttctggact aaagtaggga tatcgaccca
     6721 ttgtggttga agttgatagt tacccgattc aattttgtcg acatcaagga tttcaccaat
     6781 taagccgagg agtgattgtc cggtggcgta ggcaagtgaa atcgcctcca cccgttgttc
     6841 cttgctaaga ccagaacccg acagaagttc caggaagccc ataatggagc ttattggtgt
     6901 tcttatttcg tgactcattg ttgccagaaa ctggcttttt gcgacagttg cattgatcgc
     6961 tttatttctc tctacttcga gtgcatgaat taaatcacgc gtctcggtaa tatcttgcca
     7021 accacaaata taaacagcat
//
LOCUS       DAPOXO010000156         7033 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPOXO010000156 DAPOXO010000000
VERSION     DAPOXO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7033
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.156"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1107
                     /locus_tag="ROH59_004812"
     CDS             <1..1107
                     /locus_tag="ROH59_004812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004141771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HDX4807193.1"
                     /translation="KVLAMLVPALLVAGAANAAEIYNKNGNKVDFYGKMVGERIWSNT
                     DDNNSENEDTSYARFGVKGETQITSELTGFGQFEYNLDASKPEGENQEKTRLTFAGLK
                     YNELGSFDYGRNYGVAYDAAAYTDMLVEWGGDSWASADNFMNGRTNGVATYRNSDFFG
                     LVDGLDFAIQYQGKNSNRSTKKQNGDGYALSVDYNINGFGIVGAYSKSDRTNDQVADG
                     NGSNAELWSLAAKYDANNVYAAVMYGETRNMTPGSIDTGVADQEGNTIMRDQLINETQ
                     NFEAVVQYQFDFGLRPSLGYVYSKGKDIKGVPGHRYVDADRVNYIEVGTWYYFNKNMN
                     VYTAYKFNMLDKDDAAITGAAADDQFAVGIVYQF"
     gene            1700..2551
                     /gene="hchA"
                     /locus_tag="ROH59_004813"
     CDS             1700..2551
                     /gene="hchA"
                     /locus_tag="ROH59_004813"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HDX4807194.1"
                     /translation="MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKP
                     YRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT
                     KFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIG
                     LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHSDNPLNGYSICAFPDAADKQTP
                     DIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQE
                     MLAAYAS"
     gene            complement(2659..4017)
                     /gene="hprS"
                     /locus_tag="ROH59_004814"
     CDS             complement(2659..4017)
                     /gene="hprS"
                     /locus_tag="ROH59_004814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HprS"
                     /protein_id="HDX4807195.1"
                     /translation="MKRLSITVRLTLLFIFLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDGINKIVNRTNVSDDMLN
                     NIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVVIILCSLLSPLLIRTGLREIKKLSGVTEALNYNDSRVPVEVNALPRELKPL
                     GQALNKMHHALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICF
                     KVKCNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTK
                     INEPEKLFRRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQ
                     RN"
     gene            complement(4017..4688)
                     /gene="hprR"
                     /locus_tag="ROH59_004815"
     CDS             complement(4017..4688)
                     /gene="hprR"
                     /locus_tag="ROH59_004815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HDX4807196.1"
                     /translation="MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDD
                     YALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPF
                     SFSELLARVRAQLRQHHALNSTLEISGLKMDSVSQSVSRDNISITLTRKEFQLLWLLA
                     SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSF
                     VAVKK"
     gene            4821..5234
                     /gene="hiuH"
                     /locus_tag="ROH59_004816"
     CDS             4821..5234
                     /gene="hiuH"
                     /locus_tag="ROH59_004816"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HDX4807197.1"
                     /translation="MLKRYLVLSVATAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            5343..6347
                     /gene="msrP"
                     /locus_tag="ROH59_004817"
     CDS             5343..6347
                     /gene="msrP"
                     /locus_tag="ROH59_004817"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HDX4807198.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAAFSLPHAAHA
                     DLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            6348..6983
                     /gene="msrQ"
                     /locus_tag="ROH59_004818"
     CDS             6348..6983
                     /gene="msrQ"
                     /locus_tag="ROH59_004818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HDX4807199.1"
                     /translation="MRLTAKQVIWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLAALLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQSMQRKLGKHWQQLHNFVYLVAIL
                     TPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL"
BASE COUNT         1952 a         1655 c         1498 g         1928 t
ORIGIN      
        1 aaagttctgg caatgctggt cccggcgtta ttagttgctg gcgcagcaaa tgcggctgaa
       61 atttataata aaaatggcaa taaagttgat ttttacggca agatggttgg cgaacgcatc
      121 tggtcaaata ctgatgataa taacagcgaa aacgaagata cctcctatgc tcgtttcggt
      181 gttaaaggtg aaacccaaat caccagcgaa ctgactggtt tcggtcagtt tgaatacaac
      241 ctcgacgcca gcaagcctga aggtgaaaac caagaaaaaa cccgtttaac cttcgccggt
      301 ttgaaatata acgagttagg atcatttgac tatggccgta actacggtgt tgcttatgat
      361 gccgcagctt ataccgatat gttagttgaa tggggtggcg attcctgggc ttccgctgac
      421 aacttcatga acggtcgtac caacggtgtt gcaacctacc gtaactctga tttctttggc
      481 ctggttgatg gtcttgattt tgcgattcag taccaaggca aaaacagcaa ccgtagcact
      541 aagaaacaaa atggtgacgg ctatgcgttg tctgtagact ataacatcaa tggttttggt
      601 atcgttggtg catatagcaa atctgatcgc accaacgatc aagttgccga tggaaacggt
      661 tcaaatgctg aactgtggtc attggctgca aagtatgacg cgaacaatgt ctacgcagct
      721 gtaatgtacg gtgaaactcg taatatgact ccgggttcta ttgatacagg tgttgccgat
      781 caagaaggca atacaataat gcgtgatcaa cttatcaatg aaacccagaa ctttgaagcg
      841 gttgttcagt accaattcga ctttggtctg cgtccgtcct taggttatgt gtactctaaa
      901 ggtaaagata tcaaaggtgt acctggacat agatatgttg acgctgaccg tgtgaactac
      961 attgaagttg gtacctggta ctacttcaat aagaacatga acgtttatac tgcatacaaa
     1021 ttcaacatgc tggataaaga tgacgccgcc attactggcg cagcagctga tgaccagttt
     1081 gcagttggta tcgtctacca gttctaatca gccaacgcgc cgaggcgtgt tactgtaaaa
     1141 cataacacca gcctgagttc gtccctcatc gaactcaggc ttttttattg gcatttcatc
     1201 tccatctgcg gcacacgcaa ttgccaaagc atatcgatac agcacattac cccgcccctc
     1261 ctggctcaat aaaatctacc agcgtctctt ccagccaaca cccaaatgca tttctttatg
     1321 aattaatccg caacaaaacc gcttcccata tagaaatatt tgcaaaaata gtgcatgaaa
     1381 aaaacttttt ccctaccaat ccgggatata aatattcatc agtaccacaa cattccacag
     1441 cactaaatct ctccccatcg cccccaaacc tctgataatg gtctaaaatc attgaggcca
     1501 cttgcgacga cgttactcaa taaggaaagt ttggcgtgaa taatattcaa caccagtgca
     1561 gcatcatcat tacatactta tgcccgccaa ctaccgcttt cgatatattg actcaatttt
     1621 tcagcctggt taaaaatagc gaccagctca gtcgcaaata tagtgactac cctaactaag
     1681 caacaataag gaatacacta tgactgttca aacaagtaaa aacccgcagg tcgatattgc
     1741 tgaagataat gcgttcttcc cttcagaata ttcgcttagc caatatacga gtcccgtctc
     1801 tgatcttgat ggcgtggact atccaaaacc gtatcgcggt aaacataaaa ttctggtgat
     1861 cgccgcggac gaacgttatt tgccgaccga taacggaaaa ctgttctcga ccggtaacca
     1921 tccgattgaa acgttgctgc cgttgtatca tctccatgct gcaggtttcg aattcgaagt
     1981 ggcgaccatt tccggtctga tgaccaagtt tgaatactgg gctatgccgc acaaagatga
     2041 aaaagtaatg ccattctttg aacagcataa atcgttattc cgtaatccga agaaactcgc
     2101 ggatgttgtc gccagcctca acgctgatag cgaatatgca gcaatctttg ttcctggtgg
     2161 gcatggcgca cttattggtt taccagaaag ccaggacgtg gctgccgctt tacagtgggc
     2221 aatcaaaaat gaccgttttg ttatctccct ttgccacggt ccggcagctt ttctggcact
     2281 tcgccacagc gataacccac tgaatggtta ttctatttgc gcattcccag acgccgcaga
     2341 caaacaaacg ccagatattg gctatatgcc gggtcatctc acctggtact tcggcgaaga
     2401 gttgaagaaa atgggcatga acatcattaa tgacgacatc accgggcgag tacataagga
     2461 ccgtaaactt ctcaccggcg acagtccttt tgcagcgaat gcgttgggta aactggcggc
     2521 gcaggaaatg ctggcagctt acgcgagtta atccctgtta cattgtaatg taagcgcata
     2581 atcaatcgca gccacgttaa tactcacgac gtggctgcgt tttttcacgg ttaacttatg
     2641 gcgtactgaa gcccgatgtt aatttctttg cggtaacgta attcggaaca cgttatgctt
     2701 actgagatag tgatacgtag cacttcctcc atgtaattcg gcaatcgctt tgactaaaga
     2761 aaggccaagt ccctgaccta cggaatgacg cgaattatct ccccgccaaa atctacggaa
     2821 gagtttttca ggctcattaa ttttcgttcc aggactggcg atatcaatat taagagaacc
     2881 gttggcatca agaaaactgg ttatatgaat acgcgatttt tctggtgaat atcgaatggc
     2941 gttaacaata agattcgata acattcgttg cagtaaaatt ttatccgcaa agatttgttg
     3001 attgcacttg accttaaagc aaatctcttt ctcgtctgaa agatattcaa gatagtccaa
     3061 aagattttca acttccttat tgagagaaag cgaatccagt ttcaccaaaa cattgttttt
     3121 gtctgccctg gcaagaaaca gtatattctc tgttaaccgc gaaatatttt ccagctcttc
     3181 gatgtttccg gcaattgttt tttgatattc agcgatactt ctggtttgac tgagcgtaac
     3241 ctgattctga cccagtaatg cattaattgg cgttctaagt tcatgagcga gatcgtcagc
     3301 aaattgacta aggcgctcaa aatctttgac taaagcatga tgcattttat tcaacgcctg
     3361 cccaagaggt tttagttctc tcggtaatgc gttaacctca accggcactc ggctatcgtt
     3421 ataattcagc gcttccgtta cgccactcaa ctttttgatc tctcgcaacc ccgttctgat
     3481 taacaacgga cttaataatg agcacaatat aatgacgaca atgcaaatta taatgctatt
     3541 aattttatac tgttcaagca tattatgtct ggctgaagcc aatttagcca cagtaaccgt
     3601 taatgatggc gaaacttcat caatgttaat tcgtaaagca tctatctctg tatcattaat
     3661 aatgcttctg taaatgcctg ctgcgctgat tgtctcacta gcaggtatgt tatttaacat
     3721 gtcatcactg acatttgtcc ggttaacaat tttattgatg ccatcaccat gaatgatcaa
     3781 gatatcctga ctaacatcca tcatccggtt aaaatagaca ggtaatgtat ctggatttac
     3841 cccatcaatt aacaactgct tgatctgcgc tgtccggtta atgagtgttg tatcatcgcg
     3901 ccatttcaac tcacttgcca ggccattata gagagtccat acaattccag cgccagcaac
     3961 agacagcaga aatataaaaa gcaaggttaa acggacggtt atagataatc ttttcattat
     4021 ttttttaccg ctacgaatga atagcccatc ccccggattg tggcgattag cttttcagga
     4081 aaaggatcat caacttttgc gcggagcctg cgaatggcga catccaccgt attggtatca
     4141 ctatcaaagt tgattcccca aatttcactc gcaataaccg ttctgggtat aatctcgcca
     4201 gctctggagg ccagtagcca aagtaactga aactccttgc gcgtcagtgt aatactgata
     4261 ttgtccctgc tcacactttg actgacagag tccattttta agccactgat ttctaatgtt
     4321 gaattcaaag cgtgatgttg ccttaattgt gcccgaaccc ttgccagcaa ctcagaaaat
     4381 gaaaaaggtt ttaccagata atcatttgct ccactgtcca gccctctgac tctgtcatcg
     4441 acagaatccc ttgctgtaag gcaaataaca ggagtttgct ttgccgttct taacgtttgt
     4501 aagatctgcc agccatccat acccggaagc ataatatcca gaatgatcaa tgcataatca
     4561 tccttcagcg caagataaag cccatctctg ccatcagaaa cggcatcaat gacataaccc
     4621 gcttcggaaa gcccctgcgt tacccattcc tgggtccttt gattatcttc aataagtaga
     4681 atcttcatga aaataatatg ccataaatca tatgttatag aaacaacctg gttcattaca
     4741 aaattgtaat gctgctgtaa ggttaccctg gacgtttttt cgctatcctc aaaactcatt
     4801 cacatgacaa ggatataaac atgttaaagc gttatttagt actctcggta gcaacggcag
     4861 cattttcatt accttctttg gtttatgccg cacaacaaaa cattcttagc gtgcacattt
     4921 tgaaccagca aacaggaaaa cccgctgccg acgtgacagt cactcttgaa aagaaagcgg
     4981 ataacggctg gttacaactt aataccgcca aaacagataa ggatggacga attaaggcac
     5041 tgtggcccga gcaaactgcg actactggcg attaccgtgt cgtatttaaa accggggact
     5101 atttcaagaa acaaaatctt gaaagtttct tccctgagat ccccgttgaa tttcatatta
     5161 ataaagtgaa cgagcattat catgtgcctt tgttactcag ccaatatggg tattcaacct
     5221 atcgtggcag ttaatgcgta aatatgtaaa agctgatctc tgctactgtt agggaggtga
     5281 ctccctgaca gattaacagt aaacggctct tgttggctaa cgacaaaaaa gtgtgatggc
     5341 ttatgaaaaa gaatcaattt ttaaaagaat cagatgttac ggccgagtcg gtattcttta
     5401 tgaagcgtcg gcaggtgtta aaagcactgg gcatcagcgc agctgcattt tctttgcctc
     5461 acgctgcgca tgccgatctg cttagctggt ttaaagggaa cgatcgtccg cccgcccccg
     5521 ccggaaaacc gctggagttc agcaagcctg ccgcctggca aaataacctg ccactgacgc
     5581 cagcagataa agtctccggt tataacaact tctatgaatt cgggctggat aaagccgatc
     5641 ccgctgctaa tgctggtagc ctgaaaaccg atccatggac actgaaaatc agcggcgaag
     5701 tggcaaaacc attgaccctc gatcatgatg atttaacccg tcgcttcccg ctggaagagc
     5761 gtatttatcg tatgcgctgc gtggaagcgt ggtcgatggt ggtgccgtgg attggttttc
     5821 cgctacacaa attgctggcg cttgccgaac ccaccagcaa tgcgaaatat gtcgctttcg
     5881 aaacgattta tgcgccggaa cagatgccag gccagcagga ccgctttatc ggcggcgggc
     5941 tgaaatatcc ttatgtcgaa ggattgcgtc tcgacgaagc aatgcatccg ctcacactga
     6001 tgaccgtagg tgtttatggc aaggcgttac caccgcaaaa tggcgcgccg gtgcgactga
     6061 ttgtgccgtg gaaatatggc tttaaaggga ttaaatcgat cgtcagtatt aagctgaccc
     6121 gcgagcgtcc gccaaccacc tggaatctgg cagcgcctga cgaatacggt ttttacgcca
     6181 acgttaatcc gcatgttgat cacccgcgct ggtcacaggc taccgaacga tttattggtt
     6241 caggcggcat tctcgatgtt cagcgccagc caacactact gtttaatggt tacgccgacc
     6301 aggtggcatc gctgtatcgt ggcctggatt tgcgggagaa tttctaaatg cgcctgacag
     6361 caaaacaggt gatatggctg aaagtttgcc tgcatcttgc cggattgttg ccgtttctct
     6421 ggctggtctg ggcgatcaat cacggtggac taggtgccga tccggtgaaa gatattcagc
     6481 attttaccgg tcgcactgca ctgaaatttt tgcttgcggc cttgttaatc acacctctgg
     6541 cacgctacgc aaaacagccg ttattgatac gcactcgccg cctgttaggc ttatggtgct
     6601 ttgcctgggc gacactgcat ttaaccagtt acgcattgct ggagttgggc gtgaataatc
     6661 tggcgttatt aggtaaggag ttaattaccc ggccttattt aacgttagga attatcagct
     6721 gggttatttt gcttgcttta gcgttcactt caacccagtc gatgcagcga aaactcggca
     6781 aacactggca acagttgcat aacttcgtct atcttgtcgc gatcctgacc ccaatacatt
     6841 atctgtggtc agtgaagatt atttcaccgc agccactcat ctacgctggg ctggctgtac
     6901 tgcttttagc cttacggtat aagaagttgc tttccctttt caaccggtta cgcaagcagg
     6961 cccacaacaa attatctcta taacttcata ttgccgacaa acttcgcgtt atcccggccg
     7021 gatgcggcgc gag
//
LOCUS       DAPOXO010000157         6958 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPOXO010000157 DAPOXO010000000
VERSION     DAPOXO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6958
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.157"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1111)
                     /gene="rnd"
                     /locus_tag="ROH59_004819"
     CDS             complement(<1..1111)
                     /gene="rnd"
                     /locus_tag="ROH59_004819"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310540.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HDX4807200.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQALPEEALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYP"
     gene            complement(1193..2878)
                     /gene="fadD"
                     /locus_tag="ROH59_004820"
     CDS             complement(1193..2878)
                     /gene="fadD"
                     /locus_tag="ROH59_004820"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HDX4807201.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSL
                     TEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            complement(3083..3664)
                     /gene="yeaY"
                     /locus_tag="ROH59_004821"
     CDS             complement(3083..3664)
                     /gene="yeaY"
                     /locus_tag="ROH59_004821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HDX4807202.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVN
                     GFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPI
                     EPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            complement(3704..4399)
                     /gene="tsaB"
                     /locus_tag="ROH59_004822"
     CDS             complement(3704..4399)
                     /gene="tsaB"
                     /locus_tag="ROH59_004822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDX4807203.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPELVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLVLHDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            complement(4457..6367)
                     /locus_tag="ROH59_004823"
     CDS             complement(4457..6367)
                     /locus_tag="ROH59_004823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDX4807204.1"
                     /translation="MTDDFAQDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTIDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKTGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            6499..6843
                     /locus_tag="ROH59_004824"
     CDS             6499..6843
                     /locus_tag="ROH59_004824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDX4807205.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
BASE COUNT         1641 a         1932 c         1740 g         1645 t
ORIGIN      
        1 gtggatattc ctgcaataaa ttgtgtaatg cttccgccat cagctcacca cgccagccgg
       61 aaatcagctc cggcaaattg ttctgcggtt tcagtttcca gtgccagttc agcagttggt
      121 tgatttgccg acgcgatgcc agcaattcgg cgctgatctt gtgcgtttcg ctgacgtcag
      181 taatcagcga cttaatcgct ttaaacgctt tacgataacc cggcatgtcc atcaggttaa
      241 gcatcggctg cggtaaggcc tcttccggca atgcctgcgc tttttccacc agcgccagca
      301 acgttttacc gtggaagcgg atttcgctac cggataagcc caggctgtcc agttcgccca
      361 gacttcccgg catataacgc gctaccgacc acaaatgctc ttcacgcacg acaaagttca
      421 ccgccagatc gcgctctcgc gccttgcgca atcgccagtc ggctaacagt tgcagacagg
      481 ccagttggcg tgtgcgtaac tgccaggcat tggtgatatc acgccaggcg tcttccggcg
      541 caacgacttc ctgacgacgc atttgcatca ggcggcattc atccagcgcc gcaggtagcc
      601 agccggaggc ctccgtttct accataagct ttgcggtgat cggtaacaga taccagacat
      661 ccgccgctgc gtattcacac tgacgttcgg tcagcggtct ggccagccag tcggtgcgcg
      721 attcactctt gtccagcgta acgccggaat actcttccac catggaagcg aaaccccatg
      781 acatcgggcg tccgcagaag gcagcaagga tttgcgtgtc aatcaagggt tgtggtaatt
      841 cgccaaagac attgaggaac acttccagat cttcactgcc tgcatggaga aattttgtga
      901 tggacggatc gcgcaggatc gctttcagcg gtgaccagtc ggtgatcccg agtggatcga
      961 ttagcgccag atgctcacca tcaaaaagtt gaattaaacc cagctgcggg taataagtgc
     1021 gcgtacgaac aaattcagta tccagggcta tcgccggaaa ggcacggacg gcttcacaca
     1081 aagaagccag cgcatcgtcc gtggtaatca tttggtaatt caaattgtat tctctttagt
     1141 gggcgtcaaa aaaaacgccg gattaaccgg cgtctgacga ctgacttaac gctcaggctt
     1201 tattgtccac tttgccgcgc gcttcgtcac gtaattctcg tcgcaaaatt tttccgacgt
     1261 tagatttcgg taactcatca cgaaactcca ccagcttcgg tactttgtag cccgtgagct
     1321 gacggcggca aaaggtcacc agtgactctt cggtaagcga tggatctttt ttcactacga
     1381 agattttcac cgcttcacca ctggagccgg aaggtacgcc aacagccgcg acttcctgta
     1441 cgccaggatg ctgcatgacg acatcttcaa tctcgttggg atagacgtta aaaccggaaa
     1501 ccagaatcat atctttttta cgatcgacaa tgcgcaggaa tccttcttca tccatcaccg
     1561 cgatgtcgcc ggtgtgtaac cagccatttt tgatgatttc atcggtagca tccggacgct
     1621 gccagtaacc cagcatcacc tgcggtcctt tgacacaaag ctcacctggt tgaccaggtg
     1681 gtacttcatt atcatcatca tccaccagtt tggcttccgt cgacggcacc ggcaaaccga
     1741 tgctaccact atgataatca atatcatacg ggttaacgct gaccagcggc gcgcactcgg
     1801 tcaggccata accttccagc agatactgtc cagtcagttt aacccaacgt tctgcaacca
     1861 cttgctgaac aggcatccca ccgcctgcgg aaagatgcag actggagaaa tccagctgct
     1921 ggaactcttt attgttcagc aacgcattga acaaggtgtt aacgccagtg atagcggtaa
     1981 acggatattt cgctaactct tttaccagcc ctggaatatc gcgcgggtta gtgataagca
     2041 ggttctgccc tcccagttcg ataaacagca ggcagttaat ggtcagtgca aaaatgtgat
     2101 acagcggcag cgccgtcacc accagctctt tgcccggatg caacagcgga ccataggtcg
     2161 cgttaacctg ttccaggttc gccagcatat tgcggtgagt cagcatcgcg cctttcgcca
     2221 caccagtggt gccgccggtg tattgcagga aagctaaatc ttccggcacc aattctggtt
     2281 tgacgtactg catccggtag ccgttgtgca gggcgctacg aaatgaaatg gcatctggca
     2341 gatggtattt cggcaccaga cgcttgatgt atttaacaac gaaattgact accgtgcctt
     2401 ttgccgtaga tagctgatcg cccatacggg tcagaataac gtgctgaacg gcggttttat
     2461 caaccacttt ttccagagtg tgggcaaagt tagacacgat aacaatcgcc gatgcgccgc
     2521 tatcgttaag ctgatgctca agctcacgcg gggtatacaa cgggttaacg tttacgacga
     2581 tcatcccggc acgcaaaatg ccaaacagcg ccaccggata ttgcaataag ttaggcatca
     2641 tcaacgcaac gcgatcgcct ttcttcagcc ccaacccttg ttgcaaataa gcggcaaacg
     2701 cgcgactgcg ttcttccagt ttgcggaagg tcatcacctc ccccatattc acaaacgcgg
     2761 gttgatcggc atagcgtgcg accgactgct caaacatatc taccagagat tgataacggt
     2821 cagggttgat ctccgtcgga acgtccgcgg gataacggtt aagccaaacc ttcttcaatt
     2881 cttcacctct aaaatgcgtg ttcgtcgtca tcgcaacccc aagtgataaa catgctatta
     2941 acataatatt aactcatctt accagcttga taattaccca aggaaaaggt tgcgaagcgc
     3001 gtcactattt atttttatct ttaccgtaag aatgcagaaa cagcggaccg gccgctgttt
     3061 ctttttcttt aaaaacaagc aattattcag ttacaactgt ttgtactctc gcggggccgg
     3121 gattatacca gccccatccg ccgtagccat agggccagcc acgaccgcca taaaaccatg
     3181 gttcaatcgg ctgaggcggc ataatcacct gctgggttaa atgccaacgt ttgtaacccg
     3241 ttacttgcat caccataaat ttatagggcg tattaccgat tttgccgtca accgcaccgg
     3301 tgattggccc gactaccgtc accagttgtc cgcggaaatc caccgggtcc agaaaaccgt
     3361 tcacatcggc ataaatgcga ccgcgagaag gttctcccag cgtcggtctg gctccgctgt
     3421 ccagtggtac ggtggcaatt tccaggcggg ttttcccttg ctggttttgt acagcaacca
     3481 ctttgccgcc aaagcgagcc tcctgaccaa cgtacagctg cggcgcactc atcacccgaa
     3541 ctaaatcttg ttgcggcgtg ggactactgc ctttaatggc gtccggcaca gtaacacaac
     3601 cgctcagcat tagcgcaaac gtacctgcca gtatgccttt gataacattc ttttgaaccg
     3661 ccatgatgcg actccttttt ttctcagggc atactcttaa gattcattct ttgcccggaa
     3721 gtttcttcca tgcgacattg ttacgtaaat aaactggttc ggcatgttcc accgccaccg
     3781 ttttaccctc ggcaaacatc tggcacgcaa tcggcagcat atcttctgca gcgggcagta
     3841 acacttcgcc atcgtgcaaa accagcccgc tctctttacc gagatccggc caggcttgcc
     3901 agcccgtccc taccgtcacc cattcgccgg aaagctgttg cattcgttca tgaaccagtt
     3961 cgggtttgag tacggcttcg gtttcttcac cgtgccagat accgttttca tcacgctgat
     4021 attcggccca gtaaacttcg cccattcgcg cgtcaatagc tgccagcacg cgggttgcgc
     4081 cgtttttgcg ccacgcccct tgcgccatcg tcattagcgt ggagacgcca atcatcggca
     4141 gctctgcgcc aagtgccagc ccttgcgcaa taccaatacc aatgcgcacg ccggtaaagc
     4201 taccggggcc gcgcccgtaa gccagagcgt ttatgtcagt cagggaagtt ccgctggtgg
     4261 tcaggatatc ctgcaccatc ggtaagattc gttgagtatg ttcacgaggg caaagctcaa
     4321 aatgagcgtt gacagtaccg tcgttccaca gggcgacaga gcaggcctct gtcgcggtat
     4381 cgatagccag aattcgcatg ggtcttcgtg cttagatcaa taaaaaggcg cgcatcatac
     4441 catactccgt aacaaattac ctggaggatg gtatcgcaag gaaacgaacc gcacgggcaa
     4501 tgtcacgggt gcgcggcgct ggcggcagac tggcgagaaa cgtcgcgccg taagggcgca
     4561 tcaccagccg attgtcgcaa atcaccagca cgccgcgatc gtcggcgtcg cgaatcaatc
     4621 gccctacccc ctgcttgaga gtaatgaccg catccggcag ttgtacttca tcgaacggat
     4681 caccaccgcg caaacggcaa tcttccatgc gtgcttttaa tagtggatca tccggcgagg
     4741 taaacggcaa tttgtcgata atcaccaatg acaatgtatc gccacgcacg tccacccctt
     4801 cccagaaact gctggttgcc acaagaagcg cgttaccggc gctgacaaat tgctgcaaca
     4861 gttgcccttt gctggtttcc ccctgcaaca aaacgggaag cgtcatggta gcgcggaact
     4921 gctcggccag atcgcgcatc atggcgtgcg aggtacaaag cataaaacaa cgaccgttgt
     4981 tagcttcgat gatcggtcgc agcattgccg ccagttgccg tgcggaaccc ggttgattgg
     5041 tttgcggcag gttgcgcggc acacagagta acgcctggcg gctgtaatca aaggggctgg
     5101 gtaacagcaa tgactctgcc tgttcaatgc caagccgcga ggtgaaatga tgcagatcgt
     5161 cgttcaccga cagcgttgct gaggtaaaga tccagctacc ggttttttgc gccattaact
     5221 ctttgaattt atccgccacg ctgagcggcg tgagagccag agtaaaatgg cgcgaagtgc
     5281 attcgtacca gtagctgtag cccggctgat tgatctcttt tagccgtttc agccgtgtgc
     5341 gatataacgt ggcgcgctca aatgccgcat ccagcaaggc ggaacgcccc agcgacagtt
     5401 tcgccacgtc ataacaaagt tccagagtgt catcgagcag taaaaatgcc cgctgaattt
     5461 gcggattagc taacagctca cgcaggttac cgcgataacc aggctcaccg agttgcaggc
     5521 gaaaatcctg cgcactctgg gcaagacgat ccgcgcactt ttgtaactgc tgggtgtctt
     5581 ttaattcggt gcggtaggcg atggtgatgt cttttgccag gtcgagcagt tgtcgactgg
     5641 agagtgactg accaaaatac tggctggcaa tgtcgggcag ctggtgggct tcgtcgaaga
     5701 tcatgacgtc cgcctccggg atcagttcgc caaaaccgct ctctttcacc accatatccg
     5761 ccagaaagag atgatggttt accaccacca catcggcgtc catcgctttt ttgcgtgctt
     5821 tgaccacaaa gcaatcttta tacatcgggc agtcgctgcc gaggcagtta tcgttggtgc
     5881 tggtgaccag cggccacgcc tgtgaatctt ccgccacgct gacgcaggtg ctgatatcac
     5941 catcgattgt ttgattagac caggagcgca gcaggatcac atcgcttaag atttgtaccg
     6001 gcagatcgcc ccccgccaaa gcctgctgtt cgagacgttc gaggcagagg tagtttgagc
     6061 gccctttcag cagcgccaca ttgcccgtgt atttcaatgc ctttgagacc gttggcaaat
     6121 cgcggctgta gagctgatcc tgcaacgctt ttgagccggt cgagattatg actttctttt
     6181 tcgcccgcag cgcaggggcc aggtaagcgt aggttttgcc cgtaccggtt ccggcttcca
     6241 ccaccagcgg ctggcctttt tctatcgcct gggtgacggc taccgccatc tgtcgctgtg
     6301 gttctcgcgg cttaaagcct ggtatcgctt tcgccagctg accgtcttgt gcaaaatcgt
     6361 ccgtcacact accccctgtt gatttgaaca gggattatgt caggatgagg gcgctttcgc
     6421 cagttgaagt ggtgacggcg acctcacatt gtggcagtct ttgcagcacg aaaatggaag
     6481 tataatgagg acaaaatgat gactatcgtt cgtatcgatg ccgaagcccg ctggtctgat
     6541 gtggtaatcc acaacaacac gctctactac actggtgtac cggaaaacct cgacgccgat
     6601 gcctttgagc aaaccgccaa cacgctggcg cagattgacg ccgtgctgga aaaacagggc
     6661 agcaataaat cgagcattct ggatgccacc attttcctgg ccgataaaaa cgacttcgcg
     6721 gcgatgaata aagcgtggga tgcctgggtt gtcgcgggtc atgcgccggt gcgctgcacg
     6781 gtacaagcag gtttgatgaa cccgaagtat aaagttgaaa ttaagattgt ggctgcggtg
     6841 taagctttat cgaagcaaaa taagtcagac gataatttat cgacaatact ggtcggtttt
     6901 gcaaaaatcg accagagatt aagatattac agttgatgct cctgctaatt cattattt
//
LOCUS       DAPOXO010000158         6874 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPOXO010000158 DAPOXO010000000
VERSION     DAPOXO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6874
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.158"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            153..584
                     /gene="osmC"
                     /locus_tag="ROH59_004825"
     CDS             153..584
                     /gene="osmC"
                     /locus_tag="ROH59_004825"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HDX4807206.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
     gene            complement(774..3173)
                     /gene="dosP"
                     /locus_tag="ROH59_004826"
                     /gene_synonym="pdeO"
     CDS             complement(774..3173)
                     /gene="dosP"
                     /locus_tag="ROH59_004826"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase"
                     /protein_id="HDX4807207.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPQYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCINEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEVQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGASFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNRDYL
                     LSTAHNAMDFIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWYDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGIGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            complement(3198..3361)
                     /locus_tag="ROH59_004827"
                     /pseudo
     CDS             complement(3198..3361)
                     /locus_tag="ROH59_004827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            complement(3739..5058)
                     /locus_tag="ROH59_004828"
     CDS             complement(3739..5058)
                     /locus_tag="ROH59_004828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HDX4807208.1"
                     /translation="MDICSRNEKLAIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPVSSVNNSNPTSRARVQQQAMIDKLDHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPGSRLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPEVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
     gene            complement(5189..6724)
                     /gene="gadC"
                     /locus_tag="ROH59_004829"
     CDS             complement(5189..6724)
                     /gene="gadC"
                     /locus_tag="ROH59_004829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HDX4807209.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDAKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKSKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
BASE COUNT         1775 a         1664 c         1696 g         1739 t
ORIGIN      
        1 ttgggttata tatttccggt tatctattgt ggaaatttaa tttaagtgca gaaattatat
       61 tttcgccgga ttttattcgg attatcctgc ttatcctcgt gctgtttctc acgtagtcta
      121 taatttcctt ttaagcccac aggagagcaa caatgacaat ccataagaaa ggtcaggcac
      181 attgggaagg cgatatcaaa cgcgggaagg gaacagtatc tactgagagc ggcgtgctga
      241 accaacagcc gtatggattt aacacgcgtt ttgaaggcga aaaaggaacc aaccctgaag
      301 aactgattgg cgcagcgcat gccgcatgtt tctcaatggc gctttcatta atgctggggg
      361 aagcgggatt cacgccaaca tcgattgata ccaccgccga tgtctcgctg gataaagtgg
      421 atgccggttt tgcgattact aaaatcgcac tgaagagcga agttgcggtg ccgggtattg
      481 atgcctccac ctttgacggc attatccaga aagcaaaagc aggatgcccg gtttctcagg
      541 tactgaaagc ggaaattacg ctggattacc agttgaaatc gtaaagcgtt gccggatgac
      601 gcgtcaggcg cgtgaatgcc tgatgcgtca gcacaatcac atcaggctga gaagggattg
      661 ttctgacatg gctatgcgtt gtcgttgtcc aactaaacgt agcggaaatc acagcattta
      721 agtgacagtg tcacgttaaa taaaaacccg cgagtgcggg cgagaggaat ttatcagatt
      781 ttcagcggta acacgctgct catccagcct ggaatttctt cggcgggcag ggggcgggaa
      841 aagaaatatc cctgaataac gcgacagtgg atcttgcgta gcatctcaaa ttgctctttg
      901 gtttcgacgc cttccgccac gacggttaaa ttgaggcttt gcccaatgct ggtaatggct
      961 tcgagtaagg caaggatgcg tttttcagtc agacaacgat cgacaaaact tttgtcaatt
     1021 ttgatttccg ttaccggaag actgactaag cgggataatc cggaaaagcc cgtaccaaaa
     1081 tcatctaccg ataaaccgat gcccatatcg cgcaggatct gaatgcgctt aaagatttcg
     1141 gtatcgtgtt ccatcatcat gctttccgtg atttccaccg tcagctggtg gccgtcaata
     1201 ccccaggcgt gcattgcatc agatacctga ttaggcagct gattactgcg aaagtgcagc
     1261 gcagacaagt taacggataa cgccgggata tgaatattct ggctacgcca ttctgctaac
     1321 tgacggcaag cttccgcgat gacccagcgc ccaatatttt cgatttcacc aatctcttct
     1381 gcgagaggaa taaaccgtga agggggcaca tgaccatgca ggggatcgta ccagcgagca
     1441 agggcttcga tgccgtacag ttcacccgtt tctgcgaaga tttgcggctg ataaaccagt
     1501 ttaagttggt tattgctaat cgcttctttt agcgctgcgc ctaaaaccaa acgctctttt
     1561 accatttcgt tcatcgccgg gctgaagaac tgccagccgt taccgccatt tttgcgaata
     1621 aaatccattg cattgtgagc agtggagagc aggtaatcgc ggtttttacc cacgtcgtag
     1681 ctgatgccaa tgctcaaggt gagcgggaat ggtttatcgt caatcattat cggcttgctg
     1741 accacattcc gtagctcatc ggcgatctgg gtaatgttac tgacatcgtt ttccaggctc
     1801 acgaggacaa aagacgcacc ttcaatacga cagagatact gatccggttt gagtttttca
     1861 cgaaagcgat tgaccacttc cagcaatgcc tgatcggccc acgcatagcc aaggctatca
     1921 atcacatcct gaatatggtc aacaccgatg agatacacca ccggagagac ggctttgtcg
     1981 accaggtcat cgaggtaatt gtgcaggtta ttgcgatttg gcagaccggt catcggatca
     2041 aattggatga gttgttcaat atgctgacgg cttttttcct gttccagcgc cagcgcggcc
     2101 atatgctggc tgatatctgc cacgcgttcg ataaaggcgc tggtttctgc tcctgacgag
     2161 gttttaattt gcaggatccc cgcaggcgcg ccatcgcgct gacgaatggt cgctgaccag
     2221 ctttgcgcat tttgaacttc tgcaccgtgc gaagatgacg cccagtgtat cggcatcccg
     2281 ttgcgcagcg cgaacagaga aacatgcgat tcgttgagaa cagattcgat attacgacaa
     2341 atgatttccc ccatttcatg aaatggtggg ctgctgcaca tggcggcgag aatattgcct
     2401 tcaagctggc ggatttgcct ttcttcggtg atatccgaga atgtcattac caggttctgc
     2461 agatgcgcga gcacgtcata aaccgggctg atagaggctt taatccagat tttttcaccg
     2521 gtgcgcgtca acagcagaaa ttcgtcctga tcgcgggcgg ttttccatag caactgctgt
     2581 aaacgaatac ggttatcagc agggaattct ggaatgttca ggagtgtatc gggctgcata
     2641 ccgctggctt cgttaatgca gtaaccaaac atttcggtaa atgcgcgatt gcactgcaca
     2701 atatggcgtt ccggatcgag gacaatcacc ggtcggtcga gatggtcaac ggcaataatc
     2761 aattgtcggg tctgttcttt ttgcgccatt tctacgctgg catcccgtac cagcgccagg
     2821 taataaactt tcccctcggc gctcactttc gatagcgcaa aacgggtcca gattttactg
     2881 ccgtcttttt tctccagctg cagctcccga ctcatcccct cgacgcgcgc tttaccacct
     2941 tcacggttgt gacgaatgta ttgaggatgc gcaggacgca aatcccgcgg aatcagcata
     3001 tcaatgttat tgccaatgac ttcttcacgt ttgtaccccc agagcttctc tgcggcgggg
     3061 ttgaaaaaca tcacttcatc attttcgtta attaacaccg cgcccatcat attttgctca
     3121 agggcgggga aaaaaatgcc atcggcggca ttatccgcat cggttagctt catgattacc
     3181 tctgcatcct ggcgcatcta aagactggct ttacagagtt caacacggtt tctacctcgt
     3241 cttttgcgat atacagagct tcatcggcta tttgaatgag gcgctcatag tcaggatgac
     3301 cattaaacat ggcggcaccg atggaaagtg agagggcaat atcctcgccg tttgcggctt
     3361 taaaataatg tcgaccttta tggttaaacc gcaggccaaa atcaaccaaa cacaacgtgc
     3421 gggattggct aactgcacca tattctcctg aaatatgaag atatactgaa aagaaataag
     3481 cgacttagga cagtttcaat ctacgctact gttcttcaga agagtatagc ccatcgtaat
     3541 tatttttcgg tgacagcgaa tatcgtatgt tttttcatat tcatacattt ttattagggg
     3601 gattatggct gtttaactaa gtgtggttaa ttgcgtggtt aatttgacgt atttaagcat
     3661 gattgctagt gggatagttc aagagggtaa caagccagtg ggtaaagcac cggcttgtta
     3721 caaagtaaga atgggagttt aactgcccca acgactttgc agatagctga ccgcttgttg
     3781 agtctgcggt ttattcagat agtcctcacg gaacaagatt gtgccgctaa tttccggcac
     3841 agcatcgtta agatcgagct gctttttcag ttccggtacg ccgccgttaa tcatccagtc
     3901 tggctctatc tttgacggtt ctcctacttt atagaaggcg ataccgatat acaggcgggt
     3961 cctggtcggt ttaacgacat ccgcccacca ttttgccaac acgtcataac gcgcggcact
     4021 ccgtgagaat ggccagtaaa tttggggagc aatgtaatcc agcaaccctt gttccaccca
     4081 tcgacgggta tcagcgtagg attcgtcata ggctgccgcg cctcgggtat cggaaccgag
     4141 cggatcgtgt gatcggttac gccacacgcc tgccgggcta acgccaaatt cgacttccgg
     4201 cttaatgctt ttaatggtgt gcgaaacctt cgcaattaac tgctgggtat tgttgcgccg
     4261 ccagtctgct tttgacgcaa atgcgcctcc gtatttgcgg tacgtttcgt tatcatttag
     4321 ccgtgaacct ggtgactcag tatagaaata gtcatcaaac tgcacgccat ctaccggata
     4381 gcgggaaacc acttccgcaa ctattgatgt gatccagtcc tgaacctcag ggatgcccgg
     4441 gtcgaggaca aagcgatcgc cggacgttct gatccagtcg cggtgttgca catagacgct
     4501 ggccggttgt tgagacaggg tgctattcag ttccctgata gtaccgggct tcgtattaac
     4561 cgatacgcga taggggttaa accaggcgtg tactttcatc ccacgcttgt gggcttcgtc
     4621 gagcataaat tgcagcggat cgtaacccgg attttcacca atcttaccgg tcataagatc
     4681 ggaccacggc aaaattttcg atggccacag ggcggtacca tccggcttga cctgaaaaaa
     4741 gaccgtgttt atgccgagac gttgcagatg atccagtttg tcgatcatcg cctgttgttg
     4801 tacacgtgcc cggctggtgg ggttactatt gttaaccgag gaaaccggtg gccagtcgag
     4861 gcgagacacc gtggccagcc agatgccacg catcggttgt gacgattgtt gcgtcgtggc
     4921 tggtggcttt gagcccgctg gtggtgtcac catggactct ggaggcgtgc ttttacaact
     4981 acacagtaaa agtgccagtg caaccagtat cgctggtctt ctaatcgcta atttctcgtt
     5041 tcgggagcag atatccatat gtgctggttt ccggtaaaca gatgtgcgct cattctcgta
     5101 cttatcccgg ttaagtcaat acgacaacaa gcacgaaaaa gggagcgatg aattatcgct
     5161 cccttgtctt ataagcattc agacatggtt agtgtttctt gtcattcatc acaatatagt
     5221 gtggtgaacg tgcacgcggg tgcaggaaga agtgaccttt tggtgcgttc tgactgttga
     5281 ttggctccag agtgacgccg gtattcgctt tgcttttacg atcatgaaca gcatagagaa
     5341 taaagggcag ggcaagtacc accaggaaac taacgaccag taattcaaca tacatatcgg
     5401 tagagtcacc ctggatgtta tccggcggca ggaaggaaac aataaacgcc ataattgaag
     5461 tcagcagacc gacaatagcc acgaccagtt tcaccccttt accaccaggg atattaaatg
     5521 tgcgttttaa gtcaggatgt ttaagcacca acacaatgta gccaataaac agcatgaaat
     5581 aagcacacag ataaatcacc accgtcagcg ccagtgcgat caggaaggac atgttgttac
     5641 cgccaccggt attggtgagg atgatcaacg cgatagaagt aatcaccaac tgcgaaatga
     5701 ccagcgttac cggtacgcca tttttgttca ttttagcgaa tgccgctggc agcaggtttt
     5761 tctgcgctgt gacatacatc ccgcgagaag gaccaacaat ccaggaagcg atttccgcca
     5821 gaacacccag caacagcagt gcggagatca cgcgaaccgt ccactcaatt tccggtgcca
     5881 catgtgacat cagaacggta aaggtttgca ttacccctgc ggagaggttg atttcattac
     5941 ccggaatgac catcgcaata gacaaaccgc caacagagct taggcagatt gccgccacca
     6001 tcagcagtaa catagccagt ggatagtcgc gcccggggtt gctcatttca ttgacgtggg
     6061 ttgcggaagc ttcaacgccc atataactca aaatgaaggc aacaaataca accagggtgc
     6121 ccactttaga gaagtcaggg aagaaggtct tcgcatccat ttcgatagca acgggggcac
     6181 cggagtgcag ataaatagcc gctaatgcga tcaaaataaa tgcaggtaac aggataccgg
     6241 cgaagaagcc aactttagca attcgcgccg tgtatttcgt gccaccaaac tgcgttaatg
     6301 ccagcgccca aagaatgatg agtgctgcaa tagttttggt aatggggtct tcattcagcg
     6361 ctggccattt caggatgtag gagagtgccc ctaacacgaa atagagcatc ggaataaaac
     6421 caatggcgat ttgcagatag ccaaatgaga tcgctgcaaa tccccatctc ggccccagag
     6481 tatttgatac ccaggcgaag acgccacctt cttcccagcc gtcgacggta gccatttccg
     6541 cagcacaaag tcccacggga ataaaccata aaatcccgcc taatagcagg aagaagacta
     6601 atgaaaagcc cgatgttgcg aaggtagggt attcataaac agccattacc atcgatgccg
     6661 ttatggcaaa aaatccgagt aatgtgagct gcttagcttt acctgtctgt actgatgtag
     6721 ccatattatc cccctaaaac ggtattcctg tcggaaccgc acctgttttg ttctgaagcg
     6781 tattcagaac aatattttcc gttgctaatg ccagtgaaca gactttggaa attgtcccga
     6841 aacggcttcg tttcgggaca ccgttaccgt taaa
//
LOCUS       DAPOXO010000159         6683 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPOXO010000159 DAPOXO010000000
VERSION     DAPOXO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6683
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.159"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..951
                     /gene="araF"
                     /locus_tag="ROH59_004830"
     CDS             <1..951
                     /gene="araF"
                     /locus_tag="ROH59_004830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein AraF"
                     /protein_id="HDX4807210.1"
                     /translation="AAVMSQSAMAENLKLGFLVKQPEEPWFQTEWKFADKAGKDLGFE
                     VIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQF
                     VNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAVMAITSNELDTARR
                     RTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPEVKHWLIVGMNDST
                     VLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLLPSPDVHGYKSSEM
                     LYNWVAKGVEPTKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            1021..2535
                     /gene="araG"
                     /locus_tag="ROH59_004831"
     CDS             1021..2535
                     /gene="araG"
                     /locus_tag="ROH59_004831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP binding protein
                     AraG"
                     /protein_id="HDX4807211.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTNMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     LCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPG
                     AEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGV
                     AVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA"
     gene            2550..3536
                     /gene="araH"
                     /locus_tag="ROH59_004832"
     CDS             2550..3536
                     /gene="araH"
                     /locus_tag="ROH59_004832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter permease AraH"
                     /protein_id="HDX4807212.1"
                     /translation="MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPN
                     FATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESL
                     WIGVAAGLLLGILCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
                     SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVV
                     RTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKI
                     SYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            3703..4503
                     /gene="otsB"
                     /locus_tag="ROH59_004833"
     CDS             3703..4503
                     /gene="otsB"
                     /locus_tag="ROH59_004833"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HDX4807213.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDTILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     ARDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPKGTSKGEAITAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            4478..5902
                     /gene="otsA"
                     /locus_tag="ROH59_004834"
     CDS             4478..5902
                     /gene="otsA"
                     /locus_tag="ROH59_004834"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HDX4807214.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNKFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTACGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(5909..6337)
                     /gene="uspC"
                     /locus_tag="ROH59_004835"
     CDS             complement(5909..6337)
                     /gene="uspC"
                     /locus_tag="ROH59_004835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HDX4807215.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRNVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCRKHH
                     FDLVICGNHNHSFFSRASCSAKRVITSSEVDVLLVPLTGG"
BASE COUNT         1661 a         1549 c         1772 g         1701 t
ORIGIN      
        1 gcagccgtta tgtcacaatc cgctatggcg gagaacctga agctcggttt cctggtgaag
       61 caaccggaag agccgtggtt ccagaccgaa tggaagtttg ccgataaagc cgggaaggat
      121 ttagggtttg aagttattaa gattgccgtg ccggatggcg aaaaaacatt gaacgctatc
      181 gacagcctgg ccgccagtgg cgcgaaaggt ttcgttattt gtactccgga cccgaaactc
      241 ggctctgcca tcgtggcgaa agcgcgtggc tacgatatga aagtcattgc cgtggatgac
      301 cagtttgtta acgccaaagg taagccaatg gataccgttc cgttggtgat gatggctgcg
      361 accaaaattg gcgaacgtca gggccaggaa ctgtataaag agatgcagaa acgtggctgg
      421 gatgtcaaag aaagcgcggt gatggcgatt acctccaacg aactggatac ggctcgtcgc
      481 cgtactacgg ggtctatgga tgcgctgaaa gctgcaggat tcccggaaaa acaaatttat
      541 caggtaccga ccaaatctaa cgacatcccg ggggcatttg acgctgccaa ctcaatgctg
      601 gttcaacatc cggaagttaa acattggctg attgtcggta tgaacgacag caccgtgctg
      661 ggcggcgtac gcgcgacgga aggtcagggc tttaaagcgg ccgatatcat cggtatcggt
      721 attaacggtg tggatgcggt gagtgaactg tctaaggcgc aggcaaccgg cttctacggt
      781 tccctgctgc caagcccgga cgtacatggt tataagtcca gcgaaatgct ttacaactgg
      841 gttgcaaaag gtgttgaacc gaccaaattc accgaagtta ccgacgtggt gctgatcacg
      901 cgtgacaact ttaaagaaga actggagaaa aaaggtttag gcggtaagta atttgccgga
      961 aaaattcccc tctgcatgat gcagaggggg tgtgaacgac cagtgattca cggagacgtt
     1021 atgcaacagt ctaccccgta tctctcattt cgcggcatcg gtaaaacgtt tcccggcgtt
     1081 aaggcgctga cggatattag ttttgactgc tatgccggtc aggttcatgc gttgatgggt
     1141 gaaaatggcg caggaaaatc aactctctta aaaatcctca gcggaaacta tgcgccaacc
     1201 acgggttctg tagtgattaa tgggcaggaa atgtcctttt ccgacacgac cgcagcactt
     1261 aacgcgggtg tggcgattat ttatcaggaa ctgcatctcg tgccggaaat gaccgtcgcg
     1321 gaaaatatct atctcggcca gctgccgcat aaaggcggca ttgtgaatcg ttcattgctg
     1381 aattatgagg caggtttaca acttaaacat cttggtatgg atattgaccc ggacacgccg
     1441 ctgaaatatc tctccattgg tcagtggcag atggttgaaa tcgccaaagc gctggcgcgt
     1501 aacgccaaaa ttatcgcctt tgatgagcca accagctccc tctctgcccg cgaaatcgac
     1561 aatcttttcc gcgttattcg tgaattgcga aaagaggggc gggtgatctt atacgtttct
     1621 caccgtatgg aagaaatatt tgccctcagc gatgccatca ccgtctttaa agatgggcgt
     1681 tatgtcaaaa cttttaccaa tatgcagcag gttgaccacg acgcactggt gcaggcgatg
     1741 gtcgggcgag acattggcga tatctacggc tggcaaccgc gtagttatgg cgaggagcgg
     1801 ctgcgtcttg atgctgtgaa agcaccaggc gtgcgtacgc caataagtct ggcggttcgc
     1861 agtggagaaa ttgtcggtct gtttggtctg gtcggggcag ggcgtagcga attaatgaaa
     1921 ggcatgtttg gcgggacgca aatcaccgcc ggtcaggttt atatcgacca acagccgatc
     1981 gatattcgta aaccgagcca cgccattgcc gcaggcatga tgctctgccc ggaagatcgc
     2041 aaagcggaag gcattattcc cgtgcactcc gttcgcgaca atatcaacat cagtgccaga
     2101 cgtaaacatg tgcttggcgg ttgtgtaatc aacaacggtt gggaagaaaa caatgccgat
     2161 caccacattc gttcgctcaa catcaaaacg ccgggcgctg agcaactgat catgaatctc
     2221 tcaggcggaa atcagcaaaa agccattctg ggccgctggt tatcggaaga gatgaaggtc
     2281 attttgctgg atgaacctac gcgtggcatt gatgttggtg ctaagcatga aatttacaac
     2341 gtgatttatg cgctggcggc gcagggtgtg gcggtgctgt ttgcctccag cgacttacct
     2401 gaagtcctcg gcgttgccga ccggattgtg gtgatgcggg aaggcgaaat cgccggtgaa
     2461 ttgttacacg agcaggcaga tgagcgtcag gcactgagcc ttgcgatgcc taaagtcagc
     2521 caggcagttg cctgagtaag gagagtatga tgtcttctgt ttctacatcg ggttctggcg
     2581 cacctaagtc gtcattcagc ttcgggcgta tctgggatca gtacggcatg ctggtggtgt
     2641 ttgcggtgct ttttatcgcc tgtgccattt ttgtcccaaa ttttgccacc ttcattaata
     2701 tgaaagggtt gggcctggca atttccatgt cggggatggt ggcttgtggc atgttgttct
     2761 gccttgcttc cggtgacttt gacctttctg tcgcctccgt aattgcctgt gcgggtgtca
     2821 ccacggcggt ggttattaat ctgactgaaa gcctgtggat tggcgtggca gcggggttgc
     2881 tgctgggcat tctctgtggt ctggtcaatg gctttgttat cgccaaactc aaaataaatg
     2941 ccctgatcac gacactggca acgatgcaga ttgttcgagg tctggcgtac atcatttcag
     3001 acggtaaagc ggtcggtatc gaagatgaaa gcttctttgc ccttggttac gccaactggt
     3061 tcggtctgcc tgcgccaatc tggctcaccg tcgcgtgttt gatcatcttt ggcttgctgc
     3121 tgaataaaac cacctttggt cgtaataccc tggcgattgg cgggaacgaa gaggctgcgc
     3181 gtctggcggg tgtaccggtt gttcgcacca aaattattat ctttgttctc tctggcctgg
     3241 tatcagcgat agccggaatt attctggctt cacgtatgac cagtgggcag ccaatgacgt
     3301 cgattggtta tgagctgatt gtgatctccg cctgcgtttt aggtggcgtt tctctgaaag
     3361 gcggcatcgg aaaaatctca tatgtggtgg cgggtatctt aattttaggc accgtggaga
     3421 acgccatgaa cctgcttaat atttctcctt tcgcgcagta cgtggttcgc ggcttaatcc
     3481 tgctggcagc ggtgatcttc gaccgttaca agcaaaaagc gaaacgcact gtctgatgct
     3541 tttttctgca acaatttagc gcttttttcc tccacagcca gccgccacaa cggttggctg
     3601 ttcttcgtta caaatggcga cccccgtcac actgtctata cttacatgtc tgtaaagcgc
     3661 gttctgcgca acacaataag aaaagagaag gaggagaacc gggtgacaga accgttaacc
     3721 gaaacccctg aactatccgc gaaatatgcc tggttttttg atctcgatgg aacgctggcg
     3781 gaaatcaaac cgcatcccga tcaggtcgtc gtgcctgaca ctattctgca aggacttcag
     3841 ctactggcaa ccgcaagtga tggtgcattg gcattgattt cagggcgctc aatggtggag
     3901 cttgacgcac tggcaaaacc ttatcgcttc ccattagcgg gcgtgcatgg ggcggagcgc
     3961 cgtgacatca atggtaaaac gcatatcgtt catctgccgg atgcgattgc gcgtgatatt
     4021 agcgtgcaac tgcatacggt catcgcccag tatcccggcg cggagctgga ggcgaaaggg
     4081 atggcttttg cgctgcatta tcgccaggct ccgcagcatg aagacgcatt aatgacatta
     4141 gcgcaacgta ttactcagat ctggccacaa atggcgttac agcagggaaa gtgtgttgtc
     4201 gagatcaaac cgaaaggtac cagtaaaggt gaggcgatta ctgcctttat gcaggaagct
     4261 ccctttatcg ggcgaacgcc cgtatttctt ggcgatgatc taaccgatga atctggcttc
     4321 gcagtcgtta accggctggg cggaatgtca gtaaaaattg gcacaggtgc aactcaggca
     4381 tcatggcgac tggcgggcgt gccggatgtc tggagctggc ttgaaatgat aaccaccgca
     4441 ttacaacaaa aaagagaaaa taacaggagt gatgactatg agtcgtttag tcgtagtatc
     4501 taaccggatt gcaccaccag acgagcacgc cgccagtgcc ggtggccttg ccgttggcat
     4561 actgggggca ctgaaagccg caggtggact gtggtttggc tggagcggtg aaacagggaa
     4621 tgaggatcag ccgctaaaaa aggtgaaaaa gggtaacatt acgtgggcct cttttaacct
     4681 cagcgaacag gaccttgacg aatactacaa caaattctcc aatgccgttc tctggcccgc
     4741 ttttcattat cggctcgatc tggtgcaatt tcagcgtcct gcctgggatg gctatctacg
     4801 cgtaaatgcg ttgctggcag ataaattact gccgctgttg caagacgatg acattatctg
     4861 gatccacgat tatcacctgt tgccctttgc gcatgaatta cgcaaacggg gagtgaataa
     4921 tcgcattggt ttctttctgc atattccttt cccgacgccg gaaatcttca acgcgctgcc
     4981 gacatatgac accttgcttg aacagctttg tgattatgat ttgctgggtt tccagacgga
     5041 gaacgatcgt ctggcgttcc tggattgcct ttctaacctg acccgcgtca cgacacgtag
     5101 cgcaaaaagc catacggcct gcggcaaagc gtttcgaacg gaagtttacc cgatcggcat
     5161 tgagccgaaa gaaatagcga aacaggctgc cggtccactg ccgccaaaac tggcgcaact
     5221 caaagcagaa ctgaaaaacg tacaaaatat cttttctgtc gaacgactgg attattccaa
     5281 aggtttgccg gagcgttttc tcgcctatga agcgttactg gaaaaatatc cgcaacatca
     5341 cggtaaaatt cgttataccc agatcgcgcc aacgtctcgt ggtgatgtgc aagcctatca
     5401 ggatattcgt catcagctcg aaaatgaagc cggacgaatt aatggtaaat atgggcaatt
     5461 aggctggacg ccgctttatt atttgaatca gcattttgac cgtaaattac tgatgaaaat
     5521 attccgctac tctgacgtgg gcttagtgac gccactgcgt gacgggatga acctggtggc
     5581 aaaagagtat gttgccgctc aggacccagc caacccgggc gttcttgttc tttcgcaatt
     5641 tgcgggagcg gcaaacgagt taacgtcggc gttaattgtt aatccctacg atcgtgacga
     5701 agttgcagct gcgctggatc gtgcattgac tatgtcgctg gcggaacgta tttcccgtca
     5761 tgcagaaatg ctggacgtta tcgtgaaaaa cgatattaac cactggcagg agtgcttcat
     5821 tagcgaccta aagcagatag ttccgcgaag cgcggaaagc cagcagcgcg ataaagttgc
     5881 tacctttcct aagcttgcgt aggtgcggtt aacctcccgt aagtggaact aacagcacat
     5941 cgacctcact tgaggtaatc actcttttcg ccgagcagga tgctcgcgaa aagaaactgt
     6001 gattgtgatt accgcaaatc accaaatcga aatgatgttt gcgacaaact tccagaatat
     6061 gttcgcttaa ctcaccgtag gcaataaacg tcttgtcaac gggatacccc gcatcctgaa
     6121 ttaacttatc aagaaagctt tgcgtttctt cctgcatcac gttgcgtaaa tcttcaagca
     6181 tcggcgcagc taattgattg tacatttccg ggtcggaagc gagagtaatt aaactgatgt
     6241 gtccctttac tggcctggcg atagataccg cttttgccag cagttgctga ctttccggtg
     6301 taaccgcaac ggcgacaaga atattgctat agctcataac ctgttcctta ttctgtgaac
     6361 ttcaggtgac attaaagctt tactcctaat ggagaaacga cgcaatccca actcagttaa
     6421 acaggtaaat attagtctgg tcattagtaa atacaattaa tcaattgctc ttggttatca
     6481 tatgatttca actgtattta taagaaaata atgtactgat ttcccatatt gaacaagtgg
     6541 ttaatatatg taaagcattt tattaacatt aggttgattg ttgcctttct ttgtagttaa
     6601 ttagtttgtt gtgcggtaag tgtttgttta aaaatggctt acctggtatt gcattaaagc
     6661 gattatttat agcagatgat tat
//
LOCUS       DAPOXO010000160         6599 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPOXO010000160 DAPOXO010000000
VERSION     DAPOXO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6599
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.160"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            229..576
                     /locus_tag="ROH59_004836"
     CDS             229..576
                     /locus_tag="ROH59_004836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807216.1"
                     /translation="MTFEQKKARAIALMDSKKMWRSNYAPPLLRILWRLGIRLPPLPF
                     MPFWQVTVLTGGLWGISWGCAMWFIYWGPSGMVAGEAIIISITGGFLFGLCMASFHWW
                     RRKVNRLPPWDDV"
     gene            complement(596..1186)
                     /locus_tag="ROH59_004837"
     CDS             complement(596..1186)
                     /locus_tag="ROH59_004837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807217.1"
                     /translation="MTQSRRPSPLQRRVLIVLAALDEKRPGPVLTRDLERVLERSGEA
                     PVYGPNLRASCRRLEDAGWLRTLRAPNLQLAVELTDAGRAVAQPLLLAEQDRLRAEQR
                     AAEVVVLPLVPATGLPADGTSATDLAVELNGMTYQACRGDFVVRLDGSTCLQLWNKEG
                     RVVRLEGDPLEVAQWLQACHNAGMEVRVQVNESVTP"
     gene            complement(1186..1443)
                     /locus_tag="ROH59_004838"
     CDS             complement(1186..1443)
                     /locus_tag="ROH59_004838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807218.1"
                     /translation="MDEERVFSLSYEQLTRFAEKRIRECNLDSQGAIYLCESAKAGAV
                     LIFWHELAINGYASMNAIKRQELIDADFQRLRNLIWPEDDR"
     gene            2039..2257
                     /gene="ccdA"
                     /locus_tag="ROH59_004839"
     CDS             2039..2257
                     /gene="ccdA"
                     /locus_tag="ROH59_004839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HDX4807219.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTMQNEARRLRAERW
                     KAENQEGMVEVARFIEMNGSFADENRDW"
     gene            2259..2564
                     /gene="ccdB"
                     /locus_tag="ROH59_004840"
     CDS             2259..2564
                     /gene="ccdB"
                     /locus_tag="ROH59_004840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HDX4807220.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHVGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            2565..3372
                     /locus_tag="ROH59_004841"
                     /pseudo
     CDS             2565..3372
                     /locus_tag="ROH59_004841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016961.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
     gene            3552..4196
                     /locus_tag="ROH59_004842"
     CDS             3552..4196
                     /locus_tag="ROH59_004842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDX4807221.1"
                     /translation="MPVIANTHPKGGVGKTTSSVNIVGEMKSDTVDLDTHTGLSIILG
                     LRPEGKEISVKVPKTVDELIEIMTPYKNSDKTLLIDCGGFDSDLTRTAIAFADCVIVP
                     SKDSLTERIGLMHFDGVLDEISSIMGTDITAHLYLCKVNPNKKKFPKLDAILPSFKHL
                     KLMKSRISARAEFEDVIETGMGITESVHGRYSAGGKEVIALIEEINHLIENNKQ"
     gene            4283..4591
                     /locus_tag="ROH59_004843"
     CDS             4283..4591
                     /locus_tag="ROH59_004843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone GroEL"
                     /protein_id="HDX4807222.1"
                     /translation="MSKAKFSAQAEKLKNLVDSARLQTSSSAVTATAPSQPNEGAEEV
                     SGRPVAARTKAKNLKAIPLSYFEAHAELKATSKTSLDFSSYIIEAIREKLERDGAIGQ
                     "
     gene            5005..5985
                     /locus_tag="ROH59_004844"
     CDS             5005..5985
                     /locus_tag="ROH59_004844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HDX4807223.1"
                     /translation="MKIFIDDGSTNIKLAWLEDGDVKTLISPNSFKPEWSFSLLDDAA
                     PANYEIDGEKFSFDPLSADAVVTTETRYQYSDVNVVAIQHALQQTGLKAQPVDVIVTL
                     PISEYLDANNQKNKQNIERKKKNVMREVRVQGSDAFVIRSVSVLPESIPAGFSVLAGL
                     EDDESLLIVDLGGTTLDVSHVRSKMTGITKTWCDPNIGVSLITSGVKEQMAVHANTRV
                     SSFQADNIIVHRNEPDYLSRRIYNAEQRESIINVINERQKLLIKRVNDVISRFTDYTH
                     VMCVGGGAEIVAEAVKNLTKVPDERFYLSSSPQFDLVMGMIKMKGGVTNE"
     gene            5978..6394
                     /locus_tag="ROH59_004845"
     CDS             5978..6394
                     /locus_tag="ROH59_004845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HDX4807224.1"
                     /translation="MSDENKSRRCSFELFPDERTGDKIADELIANEKLKERGRFMRAM
                     LVTGAAFAAIDKRLPLLISELLTENTTLDDINKVISSVIPGAFSVEKKLLELLEKQSG
                     LHTSVDCSTPLTEQSLSRNDGEDQTRRNAENMFGDD"
     gene            complement(6396..>6599)
                     /locus_tag="ROH59_004846"
     CDS             complement(6396..>6599)
                     /locus_tag="ROH59_004846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
                     /protein_id="HDX4807225.1"
                     /translation="QPGLFDEIQPRKNSEKLMKTLDELNQSGKGKVWFAGRGTAPEWQ
                     MKREMLSQCYTTKWRDIPLARLG"
BASE COUNT         1660 a         1474 c         1635 g         1830 t
ORIGIN      
        1 ataccaatgg tttatattgt tatatatcag atatatgaaa ctttataata aaataattca
       61 tccgaaggat ggcttttcag aaaataattt acagatatat ccggtttcat ctggtttctc
      121 ctttattgtt atcgtgtacc ggtgcgtgat aacataacca catcatgata ataataatca
      181 ataacaataa gctgtgtcac gtttacatca tggaacggag gtgctcctgt gacctttgag
      241 cagaaaaaag cccgggccat tgccctgatg gacagcaaaa agatgtggcg gagcaattat
      301 gcccctcctc ttctgcgtat tctctggcgg ctgggtatcc ggcttccgcc attacccttt
      361 atgccgttct ggcaggtcac ggtgctgacg gggggtttat ggggcatttc ctggggatgt
      421 gcaatgtggt ttatctactg ggggccgtca ggaatggtcg caggtgaggc cattattata
      481 agtatcacgg gtggtttttt gttcggactg tgcatggcct ctttccactg gtggcgcagg
      541 aaagttaacc ggctgccacc atgggatgat gtgtaaaccg tgcacaggcg tgtttttacg
      601 gagtgacgct ttcattaacc tgtacacgaa cctccattcc ggcattgtga caggcctgca
      661 gccactgcgc cacttccagc ggatcgccct ccaggcgtac caccctgcct tctttattcc
      721 ataactgcag acaggtgctg ccgtcgagac gtaccacaaa atccccacgg caggcctgat
      781 acgtcatgcc gttcagctcc accgccagat cagtggcaga agtgccgtct gcgggcagac
      841 ctgtggccgg gaccagcggc agtacgacga cttctgccgc acgctgttct gcccggaggc
      901 ggtcctgttc tgccagcagc agaggctgtg ccacggcccg gccggcgtcc gtcagctcga
      961 cagccagctg tagattcggg gcgcgcaggg tgcgcagcca gccggcatcc tccaggcgac
     1021 ggcaggaggc gcgcaggttt ggcccgtaga ccggggcttc cccgcttcgc tccagcaccc
     1081 gttccaggtc ccgtgtcagc acggggcccg gccgtttttc atcaagggca gccagcacaa
     1141 tcagcactct ccgctgcagt ggcgacggtc ggcggctctg ggtcattacc tgtcatcctc
     1201 cggccagatg aggtttctga ggcgctgaaa gtcggcgtca atgagctcct gtctctttat
     1261 ggcattcatt gaggcatagc catttatggc cagttcatgc cagaagatca gcacggctcc
     1321 ggctttggct gactcgcaga gataaatcgc gccctggctg tccagattgc attcccggat
     1381 gcgtttttcc gcaaaccggg tcagttgttc atagctgagt gaaaacaccc tttcttcatc
     1441 catcctgcac gctccatctg ataatgttct gacaggtaaa aatcatatcc tgtatgattt
     1501 gtgtgttatt gattattgat aatatcagat attatttcat aattaatgat aaaaatcata
     1561 tctgatatga ttatatgtgt attgattatt atcatatttc ctgcccgttc cccgccgcgc
     1621 agatccggtt tccggctgtc acggatcttc ctctcccgcc gcacagcgcc atctcccgtc
     1681 agcacaacat gtagtgctga atttagctgc taatgacact atatgttgtg tcatctccct
     1741 gacctgtgat gcgccgcgca ggggcggaaa acagtgatat gatgattttc tcagcgtggt
     1801 acacttccgg aaagttgtga tattcatgaa agtcggatct gacggaaacg ggaatgcgat
     1861 aattacggtt tgtttttata agtcagattt tgatttttat tggttaacat aacgcaaggt
     1921 aaaataaata aggcttacta aaagtaagat aacagtatgt gtatttacgc gctgattttt
     1981 gcatcataat aatatatact tatatgcata cccgaagtat gtcaaaaaga ggtgtgctat
     2041 gaagcagcgt attacagtga cagttgacag cgacagctat caattgctca aggcatatga
     2101 tgtcaatatc tccggtctgg taagcacaac catgcagaat gaagcccgtc gtctgcgtgc
     2161 cgaacgctgg aaagcggaaa atcaggaagg gatggttgag gtcgcccggt ttattgaaat
     2221 gaacggctct tttgccgatg agaacaggga ctggtgaaat gcagtttaag gtttacacct
     2281 ataaaagaga gagccgttat cgtctgtttg tggatgttca gagtgacatt attgacacgc
     2341 ccgggcgacg gatggtgatc cccctggcca gtgcccgcct gctgtcagac aaagtctccc
     2401 gtgagcttta cccggtggtg catgtcgggg atgaaagctg gcgcatgatg accaccgata
     2461 tggccagtgt gccggtctcc gttatcgggg aagaagtggc tgatctcagt caccgcgaaa
     2521 atgacatcaa aaacgccatt aacctgatgt tctggggaat ataaatgtca ggctccgtta
     2581 tacacagcca gtctgcagcc agggtaccgg cagtgtattc tgccggacag tctccacaac
     2641 ttcctgttgt cattgattat ccggcagctc tggcacttcg ccagatgtcg atggttcatg
     2701 atgaactgcc gaaatatctg ctggctccgg aagtgagtgc cctgctccat tacgtcccgg
     2761 atctgcgccg caagatgctg ctggccacac tgtggaacac cgtgtgcgcg cattaatgaa
     2821 gcactggcgc tgacgcgggg ggatttttcg ctcgcgcctc cgtatccgtt tgtgcagctg
     2881 gccactctga agcagcggac cgaaaaagcc gccaggacgg caggaagaac gcctgccgga
     2941 cagcagactc accggctggt tccgctctcc gactccaggt acgtcagtca gctgcagacg
     3001 atggtggcaa cgctgaaaat tcctctggaa cggcgtaata aacgaacagg caggacagag
     3061 aaagcgcgga tctgggaagt gacggacaga acggtcagga cctggattgg ggaggcggtt
     3121 gccgccgctg ctgctgatgg tgtgacgttc tctgttccgg tcacgccaca tacgttccgc
     3181 cattcctatg cgatgcacat gctgtatgcc ggtataccac tgaaggttct gcagagcctg
     3241 atggggcata agtccatcag ctcaacggag gtctacacga aggtttttgc gctggatgtg
     3301 gctgcacggc accgggtgca gtttttgatg cctgagtccg atgcggtgtc tatgctcaaa
     3361 agaattccat aagctctgac ttttttaaat ccctttcgga tatctcatgg atatataatc
     3421 ggtatttcat attctgttga catgcaggac cggtatagag taaaaaaaca tctattgagt
     3481 acctcttgga tatccgaaag gtgtcttagg gggtctttat gggtattaca tgtggattct
     3541 ggagatacac tatgcctgtt attgctaata cgcatcccaa aggtggtgtg ggtaagacaa
     3601 cttcatccgt aaacattgtt ggtgaaatga agtctgatac agttgatctg gatactcata
     3661 ccgggctttc tatcattctg gggctgagac ctgaaggaaa agaaatttcc gtgaaagtac
     3721 ccaaaacagt ggatgagtta atcgaaatta tgactcccta caagaacagc gataagacgt
     3781 tacttattga ctgtggggga tttgactcag atcttacccg tactgcgatt gcctttgcag
     3841 actgcgttat tgttccttca aaagactccc tgactgaacg tattggtttg atgcattttg
     3901 atggagtact ggacgaaatc agctctatca tggggaccga tataactgct cacctgtatc
     3961 tctgtaaagt taatcctaac aagaagaaat tccctaagct tgatgcaatc ctgccatcgt
     4021 tcaaacatct gaagctgatg aagagccgca tttctgctcg tgcagaattt gaggatgtca
     4081 ttgagactgg gatgggaatc actgagtctg ttcatgggcg ctattcggca ggaggtaagg
     4141 aagttattgc cctgatcgaa gaaatcaatc atctgattga aaataacaaa cagtaaggtg
     4201 tgtctattgg gtatccatat agtatccttt gggcttttaa tggatatctt ttaagtatct
     4261 aacaaacatc ctgggttatc tcatgagcaa agcgaaattt agtgcacagg ctgaaaaact
     4321 gaaaaacctg gtggattctg ccagattaca aacttcttct tctgccgtaa cagcaacagc
     4381 cccgtctcag ccaaatgaag gtgcagagga agtttcaggt cgtcccgtgg ctgccaggac
     4441 gaaggctaag aatcttaagg ccataccgct gtcgtatttt gaagctcatg cggaacttaa
     4501 agcgaccagt aaaacatctc tggattttag ctcatatatt attgaggcta taagagagaa
     4561 gcttgaacgt gatggtgcaa taggtcaata aactatcgga taccttaagg gtatctgatg
     4621 tgtgtctttt aaatgcgtta tggggattct tcacgtacct aaagagtccc cattagacat
     4681 ctttctgttt atggtgacat gattcgtcac cgctttcctt tcctctcagt ttcaccattt
     4741 cattcctttt cccttaacct gaaccatgat gtccacgatg tttttatatt gcatttatgt
     4801 atcacatata accttcataa tgtttttgta tctatgattt cctctggtct taaagttgtg
     4861 tgtacaatgt acatgtaatt tatcgtgttt ttatgttgca tttgtccttt cggaaagacc
     4921 gttttttcat tataattgaa tatacattgc atgtatgagg catgtttgtt ttttctattt
     4981 gtttatgagc aacggagact ggttatgaaa atctttattg atgatggttc taccaacatt
     5041 aaacttgcct ggttggagga tggtgacgtg aaaacgttaa tcagccctaa cagctttaaa
     5101 ccggaatggt cttttagttt actggatgat gctgctccgg ctaattacga gatcgacggc
     5161 gagaagtttt catttgatcc attaagtgct gatgctgtcg taacgactga aacacgctat
     5221 cagtacagtg atgtgaatgt tgtggccatt cagcatgcgc tacagcagac cggcctgaaa
     5281 gcgcagcctg ttgatgtcat cgtcacattg ccgatctctg aataccttga cgccaacaat
     5341 cagaaaaata agcaaaacat tgaaagaaag aaaaaaaatg tgatgcgtga agtacgggtg
     5401 caggggagtg atgcatttgt tattcgcagt gtttctgttc ttcctgaaag tattcccgct
     5461 ggtttcagtg ttcttgcggg gcttgaggat gatgaatccc ttttgatcgt agatctcgga
     5521 ggtacaactc ttgatgtgtc gcatgttcgt agcaaaatga cagggattac aaaaacctgg
     5581 tgtgatccga atatcggcgt gtccctgatt acatccgggg ttaaggaaca gatggctgta
     5641 catgctaata caagagtgag ctcattccag gctgacaata tcattgtgca ccgtaatgaa
     5701 cctgactacc tttcccgtcg catttataat gctgaacagc gtgagtctat cattaatgtt
     5761 atcaatgaac ggcagaagtt gcttattaaa cgagttaatg atgtcatcag ccgtttcacc
     5821 gactatacac atgtaatgtg tgttggtggt ggggctgaaa ttgtggccga ggctgtgaag
     5881 aacctgacta aggttcctga tgagcgcttt tatctgagct catccccgca gtttgattta
     5941 gtcatgggaa tgataaaaat gaaaggtggt gtgactaatg agtgatgaaa ataaatccag
     6001 acgctgctca tttgaacttt tcccggatga acggacagga gataagatag cagatgagct
     6061 cattgcaaat gaaaaactga aggagcgggg acgtttcatg cgcgcgatgt tagttactgg
     6121 tgcggcgttt gcagctatag ataaacgtct tcctttgctg atatcggagt tactgacaga
     6181 aaatacgact ctggatgata ttaataaggt gatttccagc gtaataccag gtgctttttc
     6241 ggttgaaaag aaattgcttg aattactgga aaaacaatct ggtctccata cgtctgtgga
     6301 ttgcagtact cctcttacag agcagagtct gtcgagaaat gacggtgaag accagaccag
     6361 aagaaacgct gaaaatatgt tcggagatga ctgaactaac ccagcctggc caggggaata
     6421 tctcgccatt tagttgtata acactgactc aacatttccc gtttcatttg ccattcaggg
     6481 gcggttcctc gccccgcaaa ccacactttc ccttttcccg actggttcag ttcatcgagt
     6541 gttttcatta acttttcact gtttttacgg ggctggattt catcaaataa tcccggctg
//
LOCUS       DAPOXO010000161         6519 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.161, whole genome shotgun sequence.
ACCESSION   DAPOXO010000161 DAPOXO010000000
VERSION     DAPOXO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6519
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.161"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            209..1117
                     /locus_tag="ROH59_004847"
     CDS             209..1117
                     /locus_tag="ROH59_004847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HDX4807226.1"
                     /translation="MKAPVSITSFRPQKSIAIAIGVLAVVVLPFLSYYTVNEGERGIL
                     LRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFH
                     IKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDLQNA
                     MRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVT
                     QAQAEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVAL
                     TTAERWDGKLPDTMIPGSTVPFISTK"
     gene            complement(1324..3315)
                     /gene="tkt"
                     /locus_tag="ROH59_004848"
     CDS             complement(1324..3315)
                     /gene="tkt"
                     /locus_tag="ROH59_004848"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708699.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDX4807227.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIVGMTTFGESAPAEQLFEEFGFTVDNVVAKAKALL"
     gene            3593..4351
                     /gene="loiP"
                     /locus_tag="ROH59_004849"
                     /gene_synonym="yggG"
     CDS             3593..4351
                     /gene="loiP"
                     /locus_tag="ROH59_004849"
                     /gene_synonym="yggG"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HDX4807228.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSSGLLSSGAEAFQAYSLSDAQ
                     VKTLSDQACQDMDSKATIAPANSEYAKRLTTISRALGDNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVLGHEMGHVALGHVKKGMQVALGTNAIRVAAASA
                     GGIVGSLSQSQLGDLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGVK"
     gene            complement(4668..5588)
                     /gene="speB"
                     /locus_tag="ROH59_004850"
     CDS             complement(4668..5588)
                     /gene="speB"
                     /locus_tag="ROH59_004850"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDX4807229.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDIIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(5724..6455)
                     /locus_tag="ROH59_004851"
     CDS             complement(5724..6455)
                     /locus_tag="ROH59_004851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807230.1"
                     /translation="MKKWKLRSALIALAVLLAGCSSNAQYNSSASGNVGTAWGGDVHS
                     TVQGVSAERAWRDPAEMIVISYSTNVPSGYDRVYSIRINELEYAIRDGNFNSLPITRV
                     YDSSNNEPRYIVHARIGMNYQLYIRNYSRNTNYEIVATVDGLDVLNGKQGSLNNNGYI
                     VNAGDSLAIKGFRKDKHTEAAFQFANVADSYAANSAQGDVHNTGVIGFAAFELQGPAQ
                     NALPPCSGQAFPADNNGYAPPPCRK"
BASE COUNT         1586 a         1713 c         1686 g         1534 t
ORIGIN      
        1 ttgttatgtt tatcacaaaa taaatatttt gtttgttatt gtatttgtga tgcatatctc
       61 tatttattta ttgaatgtcc gaaagcatac ttttctaatg caatgttttt tcgctatacc
      121 cctttataga ttctgaattc tcacctgcca gctgttttct cctcccccca tgtgacatat
      181 tcccatactt tactcaagga agattcatat gaaagcacct gtttcaataa cctcatttcg
      241 cccacaaaaa tctattgcta tcgccattgg cgtgcttgcc gtggttgtgc tgccatttct
      301 ctcgtattac accgttaatg aaggtgaacg cggcattttg ctgcgctacg gaaaaatcgt
      361 aaaagttgcc gagccggggc tgggttttaa gatccctttt atggaaagtg tagagaaaat
      421 ttccacgcgt aatcaggctg tggtctatca gggattacag gcctacagcc gcgaccagca
      481 accggcacaa atgacggtat cagtcagctt ccacattaaa ccttcagaag caggcgcggt
      541 ttataccacc tacaacacca ttgaagcatt aaaagatcgt ctgattgtcc gtcagttgcc
      601 aactcaactg gagaacgttt tcggccaata taccgccatc agcgcggtac aggatcgtac
      661 aaaactggtt caggatctgc aaaatgcaat gcgtaaagcc gttgttggcc cggtggtgat
      721 tgatggtgtc cagattgaaa atattgattt ttctgacgct tatgaaaagt cgattgaaga
      781 ccgaatgaaa gcagaagtcg ccattgccac acgtaagcaa aatctggaaa cagagaaaat
      841 ccaagcgcaa atagcagtaa ctcaggccca ggcagaagca gacagtaaac tggcggcagc
      901 caaagcagaa gctgagacca ttcgcgtaag aggcgcggca gaggctgaaa ctattcgttt
      961 aaaaagtgcg gctgaagcag aagctatccg cctgcgcggt gaagctctgc gggagaatcc
     1021 cggacttgtt gccctcacca ctgctgagcg ttgggacggt aaactgcccg ataccatgat
     1081 ccccggcagc acagttccgt ttatctctac taagtaaaaa aaggccgctt tcgcggccct
     1141 tgagactgat agcaaagaca aaactgcctg atgcgctacg cttatcaggc tgcaatatgt
     1201 tgaatttgca aaatcttgta ggacggataa ggcgttcacg ccgcatccgg cataaacaac
     1261 gcgcactttg ccaacaatct gaagggccgc atttgcggcc cttctcacaa agcatcttac
     1321 cgattacagc agcgcttttg ctttcgcaac aacgttgtca acggtgaagc cgaactcttc
     1381 aaacagctgc tctgccggag cagattcacc gaaggtggtc atgccgacga tagcaccgtt
     1441 caggccaaca tacttgtacc agtagtcagc aatgccagct tccaccgcaa cacgagcggt
     1501 aaccgctttc ggcagtacgg attcacggta agccgcgtcc tgcttgtcga atgcgtcggt
     1561 agacggcatg gaaaccacgc gcgctttcac gccttcggca gtcaattttt cgtatgccgc
     1621 tacagccagt tcaacttcag aaccggtcgc gatgaagatc agttccggct gaccagcaca
     1681 gtctttcagc acataaccac cgcgcgcgat gtttgccagc tgctcttcag tacgttcctg
     1741 ctgcgccagg ttctgacggg agaggataag cgcagtcggg ccgtcctgac gttcaacgcc
     1801 gtatttccac gctaccgcgg attcaacctg gtcacacgga cgccatgtag acatgttcgg
     1861 ggtcacgcgc agagaagcga cctgctctac cggctggtga gtcgggccat cttcgcccag
     1921 accgatggag tcgtgggtgt aaaccatcac ctgacgctgt ttcatcagcg cagccatacg
     1981 tacggcgtta cgtgcgtatt ccacgaacat caggaaggtg gaggtgtacg gcaggaaacc
     2041 accgtgcagg gagataccgt tggcaatcgc agtcataccg aattcacgta caccgtagtg
     2101 gatgtagtta cccgcagcat cttcgttgat tgctttagaa ccagaccaca gggtcaggtt
     2161 agacggcgcc aggtctgcag aaccgccgag gaattccggc aacagcggcc cgaacgcttc
     2221 gatagcattc tgagacgctt tacggctggc gatcttcgcc gggttagcct gcagtttagc
     2281 aatgaactct ttcgctttcg cgtcgaagtc agacggcatt tcgcctttca tacggcgggt
     2341 aaattcagcg gcttcctgcg gataagcttt cgcgtaagca gcgaatttct cgttccatgc
     2401 ggactctttc gcctggcctg cttctttcgc atcccactga gcatagattt cagacgggat
     2461 ttcgaacggc gcgtatttcc agcccagctg ttcgcgggtc agggcaattt cagcgtcgcc
     2521 cagcggcgca ccgtgggagt cgtgggtacc ggctttgttc ggggaaccga aaccgatgat
     2581 ggttttgcac atcagcaggg acggtttgtc agtcactgcg cgcgcttctt ctactgcgcg
     2641 tttgatggat gccgcgtcat gaccgtcgat gtcgcgaata acgtgccagc cgtaagcttc
     2701 gaaacgcatt gcggtgtcgt cggtaaacca gccttcaacg tgaccatcga tagaaatacc
     2761 gttgtcatcg tagaacgcaa tcagtttacc cagcttcagc gtacccgcca gagagcaaac
     2821 ttcgtgggag atgccttcca tcatgcagcc gtcgcccatg aaggcgtagg tgtagtggtc
     2881 gacgatgtcg tggcccggac ggttaaactg cgccgccagc gttttttctg caatcgccat
     2941 accgactgcg ttggcaatac cctgacccag cggaccggtg gtggtttcta cacctgcggt
     3001 gtaacccact tccgggtggc ccggagtttt agagtgcagc tgacggaagt ttttcagttc
     3061 ttccatcggc agatcgtaac cggtgaggtg cagcaggctg tagatcagca tggagccgtg
     3121 gccgttggac agcacgaagc ggtcacggtc agcccaggac ggattctgcg ggttgtgttt
     3181 caggaaatca cgccacagga cttcggcaat gtcagccata cccatagggg cacccgggtg
     3241 accggatttg gctttctgta ctgcgtccat gctcagcgca cgaatagcat tggcaagctc
     3301 tttacgtgag gacattttga ctccagatcg gatgatgaag ggcacgccct taacgacttg
     3361 acgacagcgc gttttgggct acgccggaaa atttgccaac aatttaccgc aagccgcgcg
     3421 tcatgtacat ggaacatcct tttgccgctt cagaaatctc tggatcatgc tcgcatgttg
     3481 cgcaatctac tcgccggtcc actgcacttt tccttatact tcgattgagc gtcaattcac
     3541 ctgcagatgg cgcattttta gaataatcct gaccttgtgc ggaagagaaa acatgaaaat
     3601 tcgcgcctta ttggtagcaa tgagcgtggc aacggtactg actggttgcc agaatatgga
     3661 ctccagtgga ctgctctcat caggagcgga agcttttcag gcttacagtt tgagtgatgc
     3721 gcaggtgaaa accctgagcg atcaggcatg tcaggatatg gacagcaagg cgacgattgc
     3781 gccagccaat agcgaatacg ctaaacgtct gacgacaatt tctcgcgcgt taggcgataa
     3841 catcaatggt cagccggtga attacaaagt gtatatggcg aaggatgtga acgcctttgc
     3901 aatggctaac ggctgtatcc gcgtctatag cgggctgatg gatatgatga cggataacga
     3961 agtcgaagcg gtgctcggtc acgaaatggg gcacgtggca ttaggccatg tgaagaaagg
     4021 aatgcaggta gcacttggta caaacgcaat tcgcgttgcg gcggcctctg caggcggaat
     4081 tgtcggcagt ttgtcacaat cacaactagg agacctgggc gaaaagctag tcaattcgca
     4141 attctcccag cgccaggaag cagaggccga tgattactcc tacgatttgc tgcgccaacg
     4201 cggcatcagt ccggctggcc ttgccaccag ctttgaaaaa ctggctaaac tggaagaagg
     4261 tcgccaaagt tcaatgtttg acgaccaccc agcatccgcc gaacgcgccc aacatattcg
     4321 cgatcgtatg agcgcggatg gagttaagta aggcatggtg gtgccaaacg taggtcagat
     4381 aaggcgttta cgccgcatct gacatgaatg gcacatttgt tatcctgtgc gcgttgccgg
     4441 atgcgatgct ggcgcatctt atccagccta cgggtgccga acgtaggtcg gataaggcgc
     4501 tcacgccgca tccgacatta atggcacatt tgttatcctg tgcgcgttgc cggatgcgat
     4561 gctgacgcat cttatccggc ctacgggtgc cgagtgtagg tcggataagg cgttcacgcc
     4621 gcatccgaca ttaatgacac atcacccgtg cgcctcttat ctggcgctta ctcgcccttt
     4681 ttcgccgcct gaatatacag catctccagc gccagcgtcg ccgcagccag agcggtgatt
     4741 tccgactgat cgtatgccgg agccacttcc actacgtcca tcccaacgat gttgagatct
     4801 ttcaggccgc gtaccagttt aatggcgcga tcggaggtca ggccgccaat taccggcgta
     4861 ccggtgcctg gtgcaaaagc aggatccagg cagtcgatat caaaggtcag gtaaaccggc
     4921 atatcaccca caatctgttt cacctgggcg ataatgtcat ccacgctgcg atcgttcacc
     4981 tggcaggcgt ccagcacggt aaagccgttg tctttatcaa actcggtacg aataccaatc
     5041 tgcacggaat gattcgggtc gatcagacct tctttcggcg cggtatagaa catggtgccg
     5101 tggtcaaatt cacaaccgtt cgcataggta tcggtgtggg cgtcaaagtg taccaacgcc
     5161 attttgccga aatgcttcgc atgagcgcgc agcagcggca gcgtaacaaa gtggtcacca
     5221 ccgaaggaga gcatacgctt accggcagcc agcagcttct cggcgtgcgc ctgcagcttc
     5281 tcgctcatct cacgggcatc gccgaaggca tataccagat caccgcagtc cacgacgttc
     5341 aggcgctcac gcatgtcgaa attccacggg aagcggttgt gttcccaggc cagattcgtc
     5401 gaaacctgac ggatcgctgc cggaccgtga cgaccacccg cacgaccaga agtggccata
     5461 tcgaacggca cgccagtaat cacccagtca gcatcgctgt catacggctg gaagttcatc
     5521 ggcaggcgta aaaaaccaaa ggcgttggaa accagtgagt tatcgtattg atgacctaag
     5581 gtgctcatgg atggactcct tttacaaagt cgatataaaa aaacccttcc gcgtcgttag
     5641 gcccgacgag gaagggttgg atttgcgaaa cacaagtttg tgctaattat cgccttaaat
     5701 gggcgaggca tcaagcgagg ttgctatttc cgacacggtg gtggcgcata gccattgtta
     5761 tctgccggaa acgcttgtcc agagcacggc ggcagcgcgt tttgcgccgg gccttgtaat
     5821 tcaaaggcgg caaagccgat tacaccggta ttatgcacat cgccttgcgc cgaattggct
     5881 gcgtaggaat cagcaacgtt ggcgaactga aaagccgctt cggtatgttt atctttgcgg
     5941 aatcctttaa tcgctaacga atctccggca ttcacaatat aaccgttgtt attcagcgaa
     6001 ccttgcttgc cgttcagcac atccaggcca tcaaccgtag caacgatctc gtagttggtg
     6061 ttacgactgt aattacggat atataattga taattcattc cgattctggc atggacaata
     6121 tagcgtggtt cattattgga tgaatcataa acccgcgtaa taggtagaga attaaaatta
     6181 ccatcgcgaa tagcatattc cagttcgtta atacgaatac tataaacgcg gtcgtagccg
     6241 gaaggaacat tagtcgaata actaataacg atcatctctg ccggatcgcg ccaggctcgt
     6301 tcagcagata cgccctgaac cgttgagtgc acatccccac cccaggcggt gccgacatta
     6361 cccgatgcac tgctattata ctgcgcatta ctggaacaac cggccagcag cacggctaat
     6421 gctatcaacg cgctacgtaa tttccatttt ttcataaccg ttccctctgc atttaattaa
     6481 tgcagcgatt gtagggagat tatttaataa gaaaagcag
//
LOCUS       DAPOXO010000162         6254 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPOXO010000162 DAPOXO010000000
VERSION     DAPOXO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6254
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.162"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..559
                     /locus_tag="ROH59_004852"
     CDS             <1..559
                     /locus_tag="ROH59_004852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDX4807231.1"
                     /translation="LLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQ
                     LQSLRSLSFIERNENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLST
                     AQRQGRYKTTLQRGVMAPRLLIIDEIGYLPFGQWDQTFAGDAALTSAMLDRILHHSHV
                     VQIKGESYRLRQKRKAGVIAEANPE"
     gene            complement(626..754)
                     /locus_tag="ROH59_004853"
                     /pseudo
     CDS             complement(626..754)
                     /locus_tag="ROH59_004853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1585..2187)
                     /locus_tag="ROH59_004854"
     CDS             complement(1585..2187)
                     /locus_tag="ROH59_004854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807232.1"
                     /translation="MKQQYQTRYELLHENYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRSSPSLDDDLVVNLCTSEHLLVHHPMLEG
                     ILLSECERLKQHSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLDDWTKNLKHK
                     SEKDLEQWIIARQGQSEPLTNLMDQYVLMAYRTSVDAAHS"
     gene            complement(2281..2487)
                     /locus_tag="ROH59_004855"
     CDS             complement(2281..2487)
                     /locus_tag="ROH59_004855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HDX4807233.1"
                     /translation="MATPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKVGGFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            complement(2683..3879)
                     /locus_tag="ROH59_004856"
     CDS             complement(2683..3879)
                     /locus_tag="ROH59_004856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element ISEc20 family transposase"
                     /protein_id="HDX4807234.1"
                     /translation="MTESSDYESVQVFIGVDVGKDTHHAVAINRSGKRLFDKALPNDE
                     NKLRSLISDLKQHGQILLVVDQPATIGALPVAVARSEGVLVGYLPGLAMRRIADLHAG
                     EAKTDARDAAIIAEAARTLPHALRTLKLADEQIAELSMLCGFDDDLAAQTTQASNRIR
                     GLLTQIHPALERVLGPRLDHPAVLDLLQRYPSPEKLASLGEKKLAAQLCKLAPRLGKR
                     LAADIAQALAEQTVVVPGTNAAAVVLPRLALQLITLRKQRDEVALAVEQRVLAHPLYP
                     VLTSMPGVGVRTAARLLTEVACRAFASVAHLAAYAGLAPVTRRSGSSIRGEHPSRRGN
                     KALKRALFLSAFAALRDPLSRAYYTRKMSQGKRHNQALIALARRRCDVLFAMMRDGTF
                     YTPQAS"
     gene            4679..4819
                     /locus_tag="ROH59_004857"
     CDS             4679..4819
                     /locus_tag="ROH59_004857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001418354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulating family protein"
                     /protein_id="HDX4807235.1"
                     /translation="MNSHTRYKLTLAELEAFNSAVDNRLAELTANFTSACWLQSCHLS
                     VR"
     gene            5459..6028
                     /locus_tag="ROH59_004858"
     CDS             5459..6028
                     /locus_tag="ROH59_004858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDX4807236.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRFPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGECKGKKHYHLMLLVN
                     RDTWCRAGDYRAPGSLAGMIEQAWCSALGVDAGCHATLVHFPAWPAVWLARNDDTGFQ
                     QVLERADYLAKEHTKAHCTGERNFGCSRG"
BASE COUNT         1484 a         1564 c         1734 g         1472 t
ORIGIN      
        1 tctgcttcat gaagaaaaac tggcacgtca tcaacgtaaa caggcgatgt atacccgaat
       61 ggcagccttc ccggcggtga aaacgttcga agagtatgac ttcacattcg ccaccggagc
      121 accgcagaag caactccagt cgttacgctc actcagcttc atagaacgta atgaaaatat
      181 cgtattactg gggccatcag gtgtggggaa aacccatctg gcaatagcga tgggctatga
      241 agccgtccgt gcaggtatca aagttcgctt cacaacagca gcagatctgt tacttcagtt
      301 atctacggca caacgtcagg gccgttataa aacgacgctt cagcgtggag taatggcccc
      361 ccgcctgctc atcattgatg aaataggcta tctgccgttc gggcagtggg atcaaacgtt
      421 cgccggtgat gcagcactga cctcagcgat gctggaccgt atcttacacc actcacatgt
      481 cgttcaaatc aaaggagaaa gctatcgact cagacagaaa cgaaaagccg gggttatagc
      541 agaagctaat cctgagtaaa acggtggatc aatattgggc cgttggtgga gatataagtg
      601 gatcactttt catccgtcgt tgacacattg ccttaatctc cgcaaagata acctcgtcat
      661 tccggacatt ctctgccagg catatgtcga tgtaatccat aaacgatttc agcttaaccc
      721 ttttgtggcc ggtctttctg gctggcggtt caggggatgt tttctggtta tcgtgtacca
      781 caaaactggg atattgcccc gatagtcaca tttcagattg atcgcggtct gaagatgtgg
      841 cactgaggta acgtgctggt gtcactggta ttgctgaagt tatggttttt cggggtcagg
      901 tgagcctgtt gtgtgtatgc tttttgttca gatcagaggg gggctgtgcg gacagcggct
      961 tttgtctccg ggcattcacg cctgaacgat gaatgcgatt ttcagcaata tttgtctttg
     1021 tgacactctc tggttgagaa gctaatgcgc gcccctgttt ccacagagaa tgaggcttgc
     1081 catcagccga aacatcagta ttccacgcca tacagacggc gcctgaccat gtgctgatgc
     1141 aggtaaaatg tttcaactac aactgttcgg gttgctatgc aacgaaacag cgattctcac
     1201 gatctttaac tgcaacgttt ttccgcctga aagctgactg cctcctgctg aggtgggagg
     1261 ctatgattca gtgcgtttat agtctccggg gtatgcatgt accggagcat accatttctg
     1321 gtggataaca agccggcaca ttcagcctgc agtgaagatg gaggcacctg gttgtgaaga
     1381 acgtttctgc ccgtggctgc ttcgcatcat caatggtatt catacccgct cagaaatgac
     1441 cgggtgctga agccctccgt tatcgcgcag tataatgacg tatatgatct gtggacgagt
     1501 gagcggcgtg cctgatgtac gccgctatta ctgtatttta ccacagggct ggttttctgc
     1561 tgccagccct gtggttatca gacatcaact gtgagcggca tcaaccgatg tacggtatgc
     1621 cataagcacg tactgatcca tcagatttgt cagtggttca ctctgaccct gacgtgcaat
     1681 gatccattgc tccagatctt tttctgattt gtgtttcagg tttttcgtcc agtcgtcaag
     1741 gctgtttccg gtcattaagt caagccagca gagccagacc agtttgagac gtaactccgt
     1801 gccgccaaac tgacggaaga ggctgatcag tttgtttgcc agagaatgtt gcttcaggcg
     1861 ctcacattca gacagcagga tcccttccag catcggatga tgaaccagca ggtgttcgct
     1921 ggtgcataaa ttcaccacca gatcatcatc cagggacggg gagctccgtt tgtccggacc
     1981 ataaatcagc cggtgcagac tctggggaac gatggcaatc tccggttttt cgccattgaa
     2041 tgacacccac ccgggcgtca gattatggaa atagtagata ttcggatgac acacgcccca
     2101 tgatacggcg tgccgggtga agccggtcag ccatttctgg tagttttcat ggagcagctc
     2161 gtaacgggtc tgatactgtt gtttcatttt catattcctc acgggggata acaggcagca
     2221 gagcgccgcc ggcaggccgg agattgcgtc tgctttgggc gaagggttag tggttaaaaa
     2281 ttacggacgg gactgtgcaa tacgcgcctg cagccaggct tccacttcac ttttcagcca
     2341 gcgggagctg cgccccattt tgatgggggc aggaaagccc ccaactttga tgagtttgta
     2401 aaaccactta tcggttaagc cggtcagttg agtgataaac gccatgtcga ccatctggtc
     2461 atccatcagc gaaactgggg tagccatgag aatgttcctc cggatgttgt taaaccagcc
     2521 ggtgtggtca tgaaaacagc gcgccacctt caccggcata acaaccgggg agaaacgtaa
     2581 aaaataatcg ggaatctggc tgtccggaga taaacggggg gattgcgatg gcagagccgt
     2641 agcggaatcc cggggggtgc ccctattaag ttgtcaagca tgttatgacg cctgcggggt
     2701 ataaaaagtc ccgtcgcgca tcatggcgaa cagaacgtcg cagcgtcgtc tcgccagggc
     2761 gataagcgcc tgattgtgtc gttttccctg actcattttg cgggtgtagt aagccctgga
     2821 gagcggatcc ctgagcgcgg cgaaggccga caggaacaac gcccgtttga gagctttatt
     2881 accccgtcgc gagggatgct caccgcgtat tgacgagccg gatcgccgag ttaccggcgc
     2941 aaggccagca taagcagcga gatgtgcgac agaggcgaag gcgcggcagg cgacctcggt
     3001 gaggagtctg gctgcggtcc tgacaccgac tccgggcata ctggtcagga ccgggtaaag
     3061 agggtgagca agaactcgct gttctaccgc aagcgccacc tcgtctcttt gcttacgcag
     3121 cgtgatgagc tggagtgcca gacgtggcag tactacggca gcggcattcg tgccgggaac
     3181 gacgacggtt tgttcggcca gtgcctgagc tatgtctgct gcaaggcgtt tacccagacg
     3241 aggcgcaagt ttgcagagct gggctgccag cttcttctca cccagcgaag cgagtttttc
     3301 tggtgaggga tatcgctgga gaagatcgag taccgccggg tgatcaagtc tcggaccgag
     3361 aacgcgctcc agtgccggat gtatctgggt cagaaggccg cggatacggt tgctggcctg
     3421 cgttgtctgt gcggcaagat catcatcgaa gccgcagagc atggagagtt cggcgatttg
     3481 ctcgtcagcc agtttcagcg tgcgtagcgc gtgaggcagg gtacgggcag cttcggcaat
     3541 gatggcagcg tcacgagcat cagttttagc ttcaccggcg tgtaagtcgg ctatgcggcg
     3601 catggccagt ccagggaggt atccgacaag gactccttct gagcgggcaa cggcgacagg
     3661 taacgcaccg atggtagctg gctgatcaac aaccagcagt atctgaccat gttgtttcag
     3721 gtcagatatt agcgacctga gtttgttttc gtcgttgggt aatgctttat cgaacaggcg
     3781 tttacctgaa cgattaatgg ctacagcgtg atgcgtatct ttaccgacat caacgccgat
     3841 aaagacctgg acggattcgt aatcgctgga ttcggtcatt ctgtctccct tgtatatggg
     3901 ttaagcagat aaccacgggg agcaggtacc ggcatccacg ttacagacgg tcccggcaaa
     3961 agtgcctgac ctgaccccta ttagcggtta ccagcgcccc accagacccg gtgacatcac
     4021 cccccggatc atggacgact gggggcagta atcatgccgg gtctggctgg ctaacacccc
     4081 attataaggg gtacgaataa agtaacgggg gtgcgaaaag atgcttccgc acgcacgcgc
     4141 gataaagagg ggatagtttt cgtgaggaca gggagagaag caggcgttct gataattgca
     4201 gagttgtttt cggaggtggt tacagtgagt cagcccgttc ctggcgagca ggagactgat
     4261 atcaccgatg ggataaggtt gtctgattgg tattataaat ataagaagtc atcagagagt
     4321 aacgtaaagg atttgccaga ataacctaag agagtaaatc tctccggtaa cagagcgctg
     4381 tgaagcattc tgtatcagag tgcaaataca tgaacgctga tgcgtaaaat cagcagtgac
     4441 acgccagctc cccctatgcc cattcctgta taagacatga actgagcgta ttaatgctcc
     4501 tgccctgaga ctgagccggt gagtgagggg ctgagaaatc cctcttgaca ctgctctaac
     4561 cagaaatact tccccggttg ttgcggtgcg tccggatccc cgataacgga acactaaggc
     4621 tgtattgcgg gacaccaggt aagtggcagc ccgtaatacg tcaggagacg cgggaaaagt
     4681 gaattcccac acgcgttata aacttaccct tgcggagctg gaagccttta actctgccgt
     4741 tgacaaccgg ctggcagaac tgaccgcaaa ttttacgagt gcgtgctggc ttcagtcttg
     4801 tcacctgagc gttcggtaac ggaggcgcgg gcggtaatag actgattttc aggtattacc
     4861 ggcttacggc gtgtggttga tattgagggg ctgtgagttt cgcgtatttg tcagaaaccc
     4921 agacgagttt tcctgtatgg gacgaaataa ggcagcggca atacctggaa aaatttaata
     4981 tggtatgaag gagaacctgt cggttacgct taatataccc ggtacactgt cagctcaggg
     5041 gatacatgaa ccgttatctc accagctaca cagtatatac acactgacgc tgacagtagt
     5101 cagcaggacc acaataatca gtgccagcag tatggtaacg atacggtctg tattccggta
     5161 atagccgaag gggtcgacag aaccacaata cgggcaacac actgtattat gagtaatcgc
     5221 gtttccacag tccctgcact tctttttgcg tatcaccatc actccctcct cacagcctta
     5281 cccgtaaccg gttttttaca ttaaaaaaac aacgctgaaa attcaaccgt cagtccggag
     5341 acgaccgttc gggttatcac agagtgcctg agacagtgcc ctgccggagg tcacttcagg
     5401 gactctgcgc attttttacg acgtggctat tccgtatgaa ccatacggag atttaaccat
     5461 gacctacaaa tacaacccct tctggcagca acgtattcgt gagacagtgc ggcacgcact
     5521 gaatgttcat ccccgcctga cggcattgcg ggttgacctg cgtttcccgg atgtaccggc
     5581 agcaacggac gcagctgtga tatcccgctt catcaatgcc ctgaaagccc gaatcgacgc
     5641 ttaccagaaa cgtaagcatc gggaaggtaa acgcgtgcat cccaccactc tgcattacgt
     5701 ctgggcccgg gagtttgggg agtgcaaagg taaaaaacac tatcatctga tgctgctggt
     5761 caaccgggat acctggtgtc gtgccggtga ttaccgcgct ccgggatcac tggccggaat
     5821 gattgaacag gcctggtgca gtgccctggg ggtggatgcc ggatgccatg ccacgctggt
     5881 gcattttccg gcctggccgg cggtgtggct ggcgcgtaat gatgacaccg gctttcagca
     5941 agtgctggaa cgtgctgact atctggcgaa ggagcatacc aaagctcact gcaccggtga
     6001 gcgcaacttt ggctgcagtc gtggctgagc cagacagacg agttatctga cttcagtgtg
     6061 atgacgtgtt catggccacc acactgattt tcccttatga gactgaactg aaaccgccat
     6121 tcacacctga ccacgctgcc cgtaccggga cggctgttgc ctgcgtgtcg tctgacggta
     6181 aggaacatat actatgtacg caaaatcctt tctcgctctt gatagcaacg gacgtctgac
     6241 gggcgcccgt actg
//
LOCUS       DAPOXO010000163         6213 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.163, whole genome shotgun sequence.
ACCESSION   DAPOXO010000163 DAPOXO010000000
VERSION     DAPOXO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6213
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.163"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..62)
                     /locus_tag="ROH59_004859"
     CDS             complement(<1..62)
                     /locus_tag="ROH59_004859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4807237.1"
                     /translation="MNVGLGEGSALPVGVPVPWPT"
     gene            122..694
                     /locus_tag="ROH59_004860"
     CDS             122..694
                     /locus_tag="ROH59_004860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDX4807238.1"
                     /translation="MLIGYIRVSTNDQNTDLQRNALMCAGCEQIFEDKMSGTKSERPG
                     LKRALKCLKRGDTLVVWKLDRLGRRMKHLIALTEELRAKGVNFRSLTDSIDTSTPMGR
                     FFFHMMGALAEMERELIVERTLAGLAAARAQGRVGGRRPKLTKEQHEQIARLLQKGYD
                     RKRLAIIYDIGLSTIYRYHPVGTVITQPEM"
     gene            complement(950..2233)
                     /gene="aroA"
                     /locus_tag="ROH59_004861"
     CDS             complement(950..2233)
                     /gene="aroA"
                     /locus_tag="ROH59_004861"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDX4807239.1"
                     /translation="MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAESARELFLGNAGTAMRPL
                     AAALCLGSNDIVLSGEPRMKERPIGHLVDALRQGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIRGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPEKLKFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQPG"
     gene            complement(2304..3392)
                     /gene="serC"
                     /locus_tag="ROH59_004862"
     CDS             complement(2304..3392)
                     /gene="serC"
                     /locus_tag="ROH59_004862"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HDX4807240.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMSEWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNDSMFNTPPTFAWYLSGLVFKWLKANGGVAAMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            complement(3591..4283)
                     /locus_tag="ROH59_004863"
     CDS             complement(3591..4283)
                     /locus_tag="ROH59_004863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDX4807241.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMNAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            4413..6173
                     /locus_tag="ROH59_004864"
     CDS             4413..6173
                     /locus_tag="ROH59_004864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     accessory protein YcaO"
                     /protein_id="HDX4807242.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTIYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWSFSGTTEEEFATLMAIFKKEDKEVYIADYEHLGVYSCRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
BASE COUNT         1640 a         1562 c         1465 g         1546 t
ORIGIN      
        1 gtgggccacg gaacaggtac accaacgggc agcgccgagc cttcccccaa accaacgttt
       61 atctctcaaa tcctccccac attatctcag tactttaacc actcaaaagg gagtattttt
      121 aatgctgatt ggctacatac gtgtgtcaac aaatgaccaa aacacagatt tgcaacgcaa
      181 tgcattaatg tgcgcaggat gtgaacagat ttttgaggac aaaatgagcg gaaccaagtc
      241 ggaacgacca ggcctgaaac gcgctttaaa gtgccttaaa agaggggata cattggtggt
      301 ctggaagctg gatcggttgg gtagaagaat gaaacacctc attgctctca cagaagagct
      361 acgcgcaaaa ggtgtcaatt ttcgcagtct gacggattca atcgatacca gcactccgat
      421 gggaaggttc ttttttcata tgatgggtgc actggcagaa atggagcgtg aactgatagt
      481 tgagcgcacg ctggctggac tggctgctgc gcgagcacaa ggaagagttg gaggacgtcg
      541 cccgaaactg acgaaggagc agcatgagca gatcgcaaga ttgctccaga aagggtatga
      601 cagaaagcgg ctggcaatta tctatgatat tggactgtca acgatctacc gctatcaccc
      661 tgttgggact gtcataacgc aacctgaaat gtaattcttt ttcaaataat gaaacgccgc
      721 gtggatgcca tttatcgcac aagatagagt gcatttatcg cgcggcgcat cattcttcat
      781 gtgaatcatc cgttgattaa ttatatataa acattatgta tcaacaagtt acattgataa
      841 ttaacgctac cattaataaa aataccccac aaggtccgaa aaaaaacgcc ggcaatgtgc
      901 cgacgtcttt gaaaagaaag gattgtctat gttatcgccc gttattcatt cagccgggtt
      961 gacttatccg cgccaattgc tcgaaatagt ctggaaaagt tttagcggta cattttggat
     1021 caagaatcgt cacaggcgta tctgataatg cgaccagcga gaaacacatc gccatccggt
     1081 gatcattata agtggcgatc tcagcaaatt tcagtttttc cggtggcgta atgcgaatga
     1141 aatcatgccc ctcttcgact tccgcaccga ctttacgcag ttctgttgcc atcgcaaaca
     1201 ggcgatcggt ctctttaaca cgccagttat agatattgcg cagcgtggtg gtgccttttg
     1261 caaataacgc cgcggtggca atggtcatcg ccgcatcggg aatatggttc atatccatat
     1321 caatggcgtt cagttcacca cgcgtgcagg aaatataatc atcgccccag caaatggtcg
     1381 cgcccatttt ttccagaaca tcagcaaagc gaatatcacc ctgcatactg ttgcgtccaa
     1441 tgccggtcac ttttacagtg ccgcctctga ttgctgctgc tgccaggaaa taagaagccg
     1501 aagatgcatc gccttcaacc aaataagtgc ccggagactg gtaagactgc ccccctttta
     1561 cgacaaattg ttgatagtgc tgattttcaa tttcaacacc aaacgtcttc atcagattga
     1621 gggtgatatc gatataaggt ttagaaacca gatcgccttt aatacgaatc accgtatctt
     1681 ccggcgcaag aggcgcagtc attaacagtg cggtgaggaa ctggctggaa acggagccat
     1741 caacatcaac gttgccgcca gtaaagccgc cctgtaaacg caatggcgga taattttctt
     1801 gttccaggta agtgatcttc gccccgccct ggcgcagcgc atccaccaga tgaccaatcg
     1861 ggcgttcttt cattcgcggt tcaccgctca gtacaatatc attgctaccc aggcaaagtg
     1921 ctgccgccag cggacgcatt gccgttccgg cgttaccgag gaacaactcc cgggcacttt
     1981 ctgcgtgtaa tggaccaccg ttaccgataa tttcgcaacg cgtacgatcg gctgaaagcg
     2041 tatagcttac ccctaacgct gttaatgcat tcagcatatg gcgcacgtca tcgctatcca
     2101 gcagattggt taatactgtt ttgccgtgtg ctaatgccgc cagcaataaa gcgcggttag
     2161 aaacgctctt ggaaccgggc agattaatag tgccatcgac acgagcgatg ggttgtaacg
     2221 ttagggattc catgaactca actctctaca acagaaataa aaaccccaca ggctggctgt
     2281 ggggattatg caaaatttcg acattagccg tgacgacgtt cgaactcaac catgaagtct
     2341 gtcagtgctt taacaccttc cagcggcatg gcgttataaa tagacgcacg cattccgccg
     2401 accactcggt gacctttcag cgcatgtaag cccgcagcga aagactcttc gaggaacaat
     2461 ttatcaagcg cgctatccgc caactggaac ggcacgttca tccgcgaacg gttagctttc
     2521 gccacatcat tgcggtagaa atcgctgtta tcaatcaccc catacagcag ttctgctttt
     2581 tgctgattga tcttatccat tgcagccaca ccgccgttcg ctttcagcca tttgaagacc
     2641 aggccagata agtaccaggc aaatgtcggc ggcgtgttga acatggaatc gttatcgttg
     2701 aggatggagt aatccagaat cgatgggcag gcgatattcg ctttgcccag caaatcttca
     2761 cgaacgatga cgattgtcag gccagccggg ccgatatttt tctgcgcgcc agcgtaaatt
     2821 acaccataac ggctgacatc aatcggacgg gaaagaatgg ttgaagagaa gtcagcggcg
     2881 accaccacgt ctttaccgaa gtctggtgtt tcatcgatag cgataccatc gatggtttcg
     2941 ttcgggcagt aatgcatata agcagcatta tcagagagtt gccattcact cattggctta
     3001 actgcgcgaa gaccatcaac ggtcactttc gcatcaaaca catttggtgt gcagtatttt
     3061 ttcgcttctt tgatagcact tgctgcccag taacccgcat caacataatc tgcagtggtt
     3121 ttatcaccaa gaatattcaa cggtactgca gcaaattgac cgcgaccacc gccatggcag
     3181 aacaatactt tgtagttgga ggggacgtta agaagatcgc gaaaatcctt ctcggcttcc
     3241 tctgcaacct gaatgaactc tttgccacgg tgactcactt ccatcaccga cgtaccaaga
     3301 ccgttccagt cgcgcagttc ctgttgagcc tgtttaagca cctctgccgg tagcattgcc
     3361 ggaccagaac taaaattgaa gatttgagcc atttcccctc accacgttgc gttgctatta
     3421 acccgcggtc aatcgattgc gaccacaggt aatacattat tccagtggct atcggtttta
     3481 tcattcagtg acacacatcg caatgagtaa aaccgttgag ggcaaaaatg tggcttgcat
     3541 cacacaaaag aatctctcgg attattagca aaaagccgat gtttttgctg tcaggtcacc
     3601 cgtttagctc gacttgcctt cgtccattct ggatttgcac agcgcggaca taattgtttt
     3661 tcccccgcgt tcatatgaat gatttcactg caacggatgc aggcatagtc cgccgactcc
     3721 ggcaccactt tgtaacgctg agtacagtca ctgggtaaaa taagtaaccc cggtttcacc
     3781 ttgtcatctt caaagaaata aacactgatt tgcccgttgg tttcgagaat cgccagacgt
     3841 acctgcccca actgctctac accgcgcaat cgtagctcca taaagaactc aaattccgtc
     3901 atgttggagt tattgagttt cgaccaggcc agctcgccgt cttcaataat gacaaccggc
     3961 ttgccttcca gaagatcttc cagtttttca ctgtgcgcca tcaaccacat taccaggcgg
     4021 tataacaacg ccagagtaat aaagacgata agtaccggga ccatcggcac atcatcataa
     4081 aacgccacat ctcccgccgc tgaacccagt gtcagaatga ttaacacttc aaacagcgac
     4141 atctgccgca caccgcgtct tccggtcatt ttgaggaaca aaaaaaccag tacaaaggta
     4201 taaagactac gtagtgcaac ttcgccaagg aaatcaaaag gcactttatc aaatgccata
     4261 cggtggagat cgaacgcctt catttttatg ctcttatcgt ggtttatccg ctaaaagcat
     4321 agccaacagt tcatcggcat ggcggcggtg atagcgcctt tgagataaaa cccgtattat
     4381 tgcgcgcttt ccgtacgact aaagtgattt tcatgacgca aacatttatc cccggcaaag
     4441 atgccgctct ggaagattcc atcgctcgct tccagcaaaa actttcagac ctcggttttc
     4501 agattgaaga ggcctcctgg ctgaatcccg tgcctaatgt ctggtctgta catattcgcg
     4561 acaaagagtg cgcactgtgt tttaccaacg gtaaaggcgc aaccaaaaaa gcggcgctgg
     4621 cttctgccct cggtgaatat ttcgagcgtc tctcaaccaa ctactttttt gcggacttct
     4681 ggctgggcga aaccatcgcc aacggcccat tcgtgcatta tcccaacgaa aaatggttcc
     4741 cactgaccga aaatgacgat gtaccagaag ggctgctcga tgaccgtctg cgcgcatttt
     4801 acgatccgga gaatgaactg accggtagta tgctgattga cctgcaatcc ggtaacgaag
     4861 atcgtggtat ttgcggtcta ccgtttacgc gccagtccga caatcagacc atttatattc
     4921 cgatgaatat cattggtaac ttgtacgttt ctaacggtat gtctgctggc aatacccgta
     4981 acgaagcacg cgttcagggg ttatccgaag ttttcgaacg ttacgtgaaa aaccgcatta
     5041 ttgctgaaag catcagcttg ccggaaatcc cggcagacgt gctggcacgt tatccagcag
     5101 tagttgaagc gatcgaaacg ctggaagcgg aaggtttccc gatcttcgct tatgacggtt
     5161 cgcttggcgg ccagtatccg gtgatttgcg tggtactgtt caatcctgct aacggtacct
     5221 gctttgcctc attcggtgcg catcctgatt ttggcgttgc actggaacgt accgtgaccg
     5281 agttgctgca aggtcgtggc ctgaaagatc tggatgtgtt tactccacca accttcgatg
     5341 atgaagaagt cgctgaacat accaacctcg aaacgcactt tatcgattcc agcggtttaa
     5401 tctcctggga cctgttcaag caggatgccg attatccgtt tgttgactgg agcttctccg
     5461 gcaccacgga agaagagttc gccacgctga tggctatctt caaaaaggaa gataaagaag
     5521 tttatattgc cgattacgag catctgggtg tctactcttg ccgtattatc gtacctggca
     5581 tgtccgatat ttatccggct gaagatctgt ggttggcgaa taacagtatg ggcagccatt
     5641 tacgtgaaac gattctgtca ctgcccggta gcgagtggga aaaggaagat tacctgaacc
     5701 tcatcgagca actggatgaa gaaggttttg atgactttac ccgcgtgcgt gaactgttgg
     5761 gcctggcgac cgggtcggat aacggctggt acactctgcg tatcggtgaa ttaaaagcca
     5821 tgctggcgct ggctggtggc gatctggaac aggctctggt ctggaccgaa tggacgatgg
     5881 agtttaactc atcagtattc agcccggaac gcgccaatta ttatcgctgc ctgcaaacat
     5941 tgttattact ggcgcaggaa gaagatcgcc agccgctgca atatctgaat gcgtttgttc
     6001 gcatgtacgg cgcagatgcc gtggaagccg ccagtgcagc aatgagcggc gaagcggcgt
     6061 tttatggctt gcaaccagta gatagcgatc tgcacgcgtt tgctgcacat cagtcgttgt
     6121 tgaaggccta cgaaaagctg caacgcgcca aagcagcatt ctgggcaaaa taaaatcaaa
     6181 tagcctacgc aatgtaggct taatgattcg tct
//
LOCUS       DAPOXO010000164         6184 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.164, whole genome shotgun sequence.
ACCESSION   DAPOXO010000164 DAPOXO010000000
VERSION     DAPOXO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6184
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.164"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            859..1494
                     /locus_tag="ROH59_004865"
     CDS             859..1494
                     /locus_tag="ROH59_004865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDX4807243.1"
                     /translation="MNDNIYKYSKDNAIAFLLLVVISTVVIFTPAFTIQYIGLDLAFS
                     FVFITEILISTSFYIFYLRRIPGCKITIKTNAKTLKLLVISFAVIALMQLLIFAYRDN
                     LNNSESTSLNWIEIFILVLIVPYYEEIVYRTCLFGLLCTIYKKELFTPCMCTSLFFCL
                     MHPQYYNVADQIILFIMSMLLLNIRICSKGIFYPMLLHAEINGFVILLNIL"
     gene            1597..2850
                     /locus_tag="ROH59_004866"
     CDS             1597..2850
                     /locus_tag="ROH59_004866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HDX4807244.1"
                     /translation="MNIFRSEAIEHHNDTEYGDIILPTSFSLSVCATVTLFIMLSLTV
                     FIYYGSYTRKAHLTGIVMPSSGLVKIIPQYAGYVTQLTVSEGEHVTAGTQLYHISGEH
                     YNGNGTGTLATMSISLKTQYIMLASQQSFESRDNSQQQEAVRQRMVSLEPQIRSAEQR
                     LQLAERQAELAISVMERYKKLAGTHYVSDIEFQQKQIDVSAAQQNVEDQRQGLLQLHT
                     AMDTAKDELNHLIVQGKSRKAELDRQLQVLKQQQDELAGQEKFTLRAPVSGTIAAVLI
                     KQGQSVKASEPVMTLIPDNAHLQIELYATSKKAGFIRPGQRVSLKFSAFPYQKFGIQY
                     GTIREISHTTLAPSDLLPVSPVTWKENEGHYRVIVEPENTFIFAYGKKEPLRPGMTLE
                     GDVNLDTRHLWEWLTEPLWSMKGNL"
     gene            2850..5045
                     /locus_tag="ROH59_004867"
     CDS             2850..5045
                     /locus_tag="ROH59_004867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HDX4807245.1"
                     /translation="MESINWKVRKQLPVIRQTESAECGLACLAMIACWHGLKTDLSTL
                     RERFNIGIQGMTLQRLIECAASIHLSSRAVRLEPEDLRCLNLPSILHWDMNHFVVLHK
                     VRGNRLYIHDPDRGKITISLLDAGKHFTGVALELTPASDFTPRNERKKIHLRQLTGKT
                     PGLLASMTKIIIFALALEILALGGPLLNQLVIDEVLVAADRSLLYVIIVALLLLSLIQ
                     LLLSLARQWATISLSVNFNMQWTARVFHHLVRLPLAWFDARSKGSINARFEAVDIIQQ
                     ALTTQVLEGILDMLLIVTALCMMLLYSPGMTLIAVIAAIIYGALRALWYPALRQSVED
                     VWDAGTKESGHFLETLNGIQSLRINGVTIHREAAWLNLNVTRRNTQLRQNRLQMSYEL
                     THTLTESVVSAIILWQGAVEVLDGTFTVGMLVAYLSYQIRFSSSISNLTDNFFSWRML
                     DVYNERLADIVLTPQEGHQNQHHWANHNETISASQYREYKYDNTHPPLLIEKITFSHK
                     GADKPILYNASLMLFPREILAITGKSGCGKSTLVKLILGIHTPSEGRINAFGIPHTHS
                     DYFQVRQRIGTVLQDDYLFKGSIADNIMFFSEIRDHEHMRKCASLALIDSDIMAMPMG
                     YQTLLGETGGGLSGGQKQRILLARALYKKPGLLLLDEATSHLDVESEIEISQTLRQLG
                     IPVLLIAHRPETIASADRVLYLRDGHFSEITYRPARTHNINNHPNGGDF"
     gene            complement(5088..5660)
                     /locus_tag="ROH59_004868"
     CDS             complement(5088..5660)
                     /locus_tag="ROH59_004868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807246.1"
                     /translation="MAYVDDFKEAIIRTRRLQLAQPVDLCETHTRIMNDKRIRHLGGI
                     IRPVLDLNSGYEQLVARCMPVHLQARPLVEEWLGCPVYFTLGWIDDGTPKGMFRFDED
                     FITDTLKNGYTGDTVNLHAWLTLPSMEIIDITLSTTISMLQGHKNQLGGVIIKRADDI
                     KGFSYKPMLIGDEFLSKSGILHKFTYLELN"
     gene            complement(5686..>6184)
                     /locus_tag="ROH59_004869"
     CDS             complement(5686..>6184)
                     /locus_tag="ROH59_004869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="relaxase NikB"
                     /protein_id="HDX4807247.1"
                     /translation="SRTTTTDRCVVLCEPGGTPVYGNTGDLETRLQKNGSVRFRDRRT
                     GEFVCTDYGDRVVFRNHHDRNALADKLDLIAPVLFERDPRMSFEPEGNDGQFNQVFAE
                     MVAWHNVTGFSEHGNYVITRPDVDQHREVSERGYRNYMDSNTYRDGTQPVQDSENRWE
                     PPTPV"
BASE COUNT         1907 a         1265 c         1233 g         1779 t
ORIGIN      
        1 tttagagtaa cgttgggttt ttctgctcat tattagctca ttctgatgcc attctatttc
       61 aggaaggagt gtccgttaaa ctcaggctac ctcaggttca gttttatatc ttcacacgat
      121 gatatttttg taattacaca acctcgaaaa cacacaaata ttttcacaca tttacagtta
      181 atcacacaat ttcactttca ttacattttt gttattggct atcttgaacg cacagaataa
      241 caaacaacca ataggggaaa tatgatatgg caagtataag agaattaact ttagatgaga
      301 taacgcttgt cagcggagga aacgcaaaca gcaactttga aggtggcccc cgtaatgacc
      361 gttccagtgg ggctcgtaac tcactgggtc gaaacgcacc aactcatatt tatagtgatc
      421 caagcactgt aaaatgcgct aacgctgtat ttagtggaat gattggtggt gcgatcaaag
      481 gaggtcctat aggaatggca agaggtacca ttggtggagc cgttgttggt caatgtctct
      541 cagatcatgg tagtggaaat ggaggtggta acagaggaag ttccaatagt tgctcaggta
      601 ataatgttgg cggaacatgt aaccgataaa tagatataat ggagggcgct actatgttta
      661 ttaaattact ttcctttata tgtggtttgt tactgggatt tgcactattg agtggctcct
      721 ctgttattga tttatactgg ttttcactac cttccgagtt ttcaaagatt gtagtcatgc
      781 tgatcactct tttttccaca gcaagattca tggactatat catagaaaaa ataagaacaa
      841 tctccgcgaa atagcattat gaatgataac atatataaat acagtaaaga taatgcgata
      901 gcgtttcttc tacttgttgt tatatcaaca gttgtgatat tcacaccggc gttcaccata
      961 caatatattg gtttggatct ggcattttcc tttgtcttta ttactgaaat tttaatatca
     1021 acttcatttt atatttttta cttaagaaga ataccaggtt gtaaaatcac cataaagaca
     1081 aatgcgaaaa cattaaagct attagtaata tcatttgctg taattgctct catgcaactg
     1141 cttatttttg cttatagaga caatttgaac aatagtgaat caacttcact taattggatt
     1201 gaaatattta tactggtcct gatagttccg tattatgaag aaattgttta ccgaacatgt
     1261 ctattcggcc ttctatgtac gatttataaa aaagaattat tcactccctg catgtgtaca
     1321 tctttatttt tctgtctgat gcatccgcag tattataatg tggctgatca aattattctg
     1381 tttattatgt caatgttatt gttgaatata aggatttgca gtaaggggat tttctatcca
     1441 atgctgttac atgcggaaat aaacggcttt gttatattgt taaatatatt atagtataaa
     1501 actttaacat cacacaggta agatgcatat caaatattaa tattattcaa ccaaaacctc
     1561 ttgttgacgg aaaggttact tattgtatta aaaagaatga atatattcag aagtgaagca
     1621 atagaacatc ataatgacac tgaatatggt gacattattt taccaacatc atttagccta
     1681 tcagtatgtg caacagttac attattcatt atgttaagtc tgactgtatt catctattac
     1741 ggtagctata caaggaaagc gcatcttaca ggtatcgtca tgccctcatc aggactggta
     1801 aaaataattc ctcaatatgc aggatatgta acacaactga ctgtatccga aggagaacac
     1861 gtaactgcag ggacacaact ctatcatata agtggagaac attataacgg taacggaact
     1921 ggcacattag caacgatgag tatttccctg aagactcagt atattatgtt ggcctcccag
     1981 caatcctttg agtcgcgaga taatagtcaa caacaggaag ccgtacggca aaggatggta
     2041 tcacttgagc cacaaataag aagtgcagaa caaagacttc agcttgctga acgtcaggca
     2101 gaactggcta tatccgtcat ggaacgctat aaaaaattgg ctggtacgca ttatgtgtca
     2161 gatatcgaat tccaacagaa acaaattgat gtttctgccg ctcaacaaaa cgttgaagat
     2221 cagcgtcagg ggcttctcca gttgcatact gcaatggaca cagccaaaga tgaactaaat
     2281 catcttattg ttcaggggaa aagccgtaaa gcagaactcg acagacaatt gcaggtgcta
     2341 aaacaacaac aggatgaact ggccggacaa gaaaaattta cactgagggc tccagtatcc
     2401 gggactattg ctgctgtact gatcaaacag gggcagtctg tgaaagcatc tgaaccggtc
     2461 atgactctca ttcccgataa tgctcattta caaattgagc tttatgctac cagcaagaaa
     2521 gccggtttta tccgaccagg tcaacgggta tctctgaagt tttcggcctt cccttatcag
     2581 aaatttggta tccagtacgg cacaattcgt gaaatcagtc atacgaccct ggctccttcc
     2641 gacttattac cagtctcacc cgtcacatgg aaagaaaacg aagggcatta tcgcgttatt
     2701 gttgaacctg aaaatacatt tatatttgca tacggaaaaa aagaaccgct aagaccaggc
     2761 atgactctgg aaggagacgt caaccttgat actcgtcatt tatgggaatg gctgacagag
     2821 cccctatgga gtatgaaagg aaatctgtaa tggaatcaat aaactggaaa gtaaggaaac
     2881 aactacccgt tatccgtcaa accgaatcag ctgaatgcgg tctggcgtgt ctggctatga
     2941 ttgcctgctg gcatggactg aaaacagatt tatcgacatt acgggaacgt ttcaatatag
     3001 gtattcaggg aatgacgcta caaaggttga tcgaatgtgc agcgtccatc catttatcat
     3061 cacgtgcagt tcgtctggaa cccgaagatc tgaggtgtct taatcttcca tctattctgc
     3121 actgggatat gaaccatttc gtcgttctcc ataaagttcg gggaaaccgg ttatacatcc
     3181 atgatccgga cagaggaaaa attacaataa gtctgttgga cgcaggtaag cattttacag
     3241 gagtggcact ggaattaact ccagccagtg atttcacccc ccggaacgag agaaaaaaaa
     3301 tccacctgcg tcaactgaca gggaaaaccc cggggctttt agcatcaatg acaaaaatta
     3361 ttatttttgc tctggccctt gagattctgg ctttaggtgg tccacttctt aatcaactgg
     3421 taattgatga agttctggtc gcagcagaca gaagtctatt gtatgtcatt atagtggcac
     3481 tactgttgtt atcactcata caattattac tctccctggc acgacaatgg gcaacgatca
     3541 gtttatccgt caattttaac atgcaatgga ctgccagagt tttccatcat cttgtaagac
     3601 tccctcttgc atggttcgat gcccgaagta aaggaagtat taatgcccgt tttgaagcag
     3661 tagatataat ccagcaggcg ctgacaacgc aggttcttga aggcattctg gatatgctac
     3721 ttattgtgac tgctctttgc atgatgttgt tgtatagccc aggaatgaca ttaatcgcag
     3781 taattgcagc tattatatat ggcgcactga gagcattgtg gtatccggct ttacggcaat
     3841 ctgttgaaga tgtctgggat gcaggaacta aggagtcggg gcattttctc gaaaccctta
     3901 acggcattca gagtctgaga atcaacggtg taactattca cagagaagcg gcctggctga
     3961 acctcaacgt tacccgcaga aacacacagc tacgccagaa tcgtttacaa atgagctatg
     4021 aactgacgca tacactgacg gaaagtgtag tttcagccat tattttgtgg cagggtgcag
     4081 tagaagtgct ggatgggaca tttaccgtgg gtatgttggt tgcttactta tcctatcaga
     4141 tacgtttttc atccagtata agcaatctga ctgataactt tttttcctgg cgcatgcttg
     4201 atgtttataa cgagagactt gccgatattg tgctaacacc acaggaaggt caccagaatc
     4261 agcaccattg ggcaaaccat aatgaaacaa tatctgcaag ccagtacaga gaatataaat
     4321 atgataatac ccatccacca ttacttatcg aaaaaataac atttagccat aagggcgcag
     4381 ataaacccat attgtataac gcgtcactaa tgctctttcc tagagaaata ttagcaataa
     4441 caggtaaatc aggatgtggc aaatcaacat tggtaaagct tattcttgga attcatacac
     4501 ccagtgaagg aagaattaat gcatttggca taccacatac acattctgat tattttcagg
     4561 ttcgtcaacg aattggcact gtattgcaag atgactatct tttcaaaggt tctatagctg
     4621 ataatataat gttttttagc gaaattagag atcatgaaca catgcgtaaa tgcgcaagtc
     4681 tggcacttat agacagtgat attatggcaa tgccaatggg ctatcaaaca ttgcttggag
     4741 aaaccggagg gggactttca ggtggtcaga agcaacgtat tctactggca agagcactgt
     4801 ataaaaaacc cggtctatta ttactggacg aagcaaccag tcatcttgat gtggaaagtg
     4861 aaatagaaat aagccagaca ttacgccaac tcggaattcc tgttctgtta atagctcatc
     4921 gaccagaaac aatagcatcc gcagacagag ttctgtatct gagagatggt cacttttcgg
     4981 aaataacata tcgacctgcc agaactcata atataaataa tcaccccaac ggaggtgatt
     5041 tctgaacaga gataagaacg tcaaaaaacc agtttattta aaaatcacta gttcaattct
     5101 agatatgtaa acttatgcaa tataccagat tttgacagga attcatcacc aataagcatt
     5161 ggcttatatg agaagccttt aatatcatca gctctcttga taataacacc gcctaactga
     5221 ttcttatgcc cctgcaacat agaaattgtt gttgataatg tgatatctat aatttccata
     5281 ctgggtaaag ttagccatgc atgaagattg acagtatctc ctgtataacc atttttcaat
     5341 gtatcagtaa taaagtcctc atcaaacctg aacatacctt ttggggtccc atcatcaatc
     5401 catcccaacg taaaataaac aggacatccc agccattctt caaccaaagg tctggcttga
     5461 agatgaacag gcatacatcg cgcaaccagt tgttcatacc cagaattcag atccagtaca
     5521 ggacgtataa ttcctcccaa atggcggatt cgtttatcgt tcattatgcg agtatgcgtc
     5581 tcacataaat caacgggttg tgcaagttgt aaccgccgag tcctaatgat tgcttcttta
     5641 aaatcatcga cataagccat aacaatctcc cgtttataac attctttaca ccggtgttgg
     5701 aggttcccag cgattctcac tatcctgaac tggctgagtt ccatctctgt aagtgttact
     5761 atccatgtaa ttgcgatagc cccgctcact cacttccctg tgctgatcta cgtccggtcg
     5821 agtaataacg taatttccat gttcagagaa tcccgtcaca ttgtgccatg ccaccatttc
     5881 agcaaagacc tgattaaact gtccatcgtt tccttctggt tcaaagctca ttctgggatc
     5941 acgctcaaac aatacaggtg caatcaaatc cagtttatct gccagcgcat tgcggtcatg
     6001 gtgattacgg aaaacaaccc tgtcaccata atccgtacag acaaactctc ccgtccgacg
     6061 gtcacggaaa cgaacactcc cgttcttctg cagacgggtt tcgagatcac cggtattacc
     6121 gtataccggc gttccgcccg gttcacaaag cacgacacag cggtctgtcg ttgttgtgcg
     6181 tgac
//
LOCUS       DAPOXO010000165         6175 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.165, whole genome shotgun sequence.
ACCESSION   DAPOXO010000165 DAPOXO010000000
VERSION     DAPOXO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6175
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.165"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(13..1197)
                     /locus_tag="ROH59_004870"
     CDS             complement(13..1197)
                     /locus_tag="ROH59_004870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4807248.1"
                     /translation="MAENKIYAVLTDRGAQLEAAALASGVPVVLNKFVIGDANGNDDV
                     TPDPARTALIHETYRGDIKSAENSGNQVIFTLYVPPDTGGYTIREVGILTDKGELYSV
                     ARSPDILKPTDSNGALISITYKYTLAVSSTSTVNVVVYDNYVTPEEADKKYLQISKNL
                     SEIPANGETAQQAARKNIGIDGDVAYRDKGNAFTHPNTFKDDVIFEDVLSSKKQININ
                     KPGTDLTLFSFAGLSDVSGDYLDFSTRGENNQKVFYRLRGVHYDGLVLLCGGQTYKYW
                     NEANLKPVKTINGESPDENGNIDISLSPDPSPEIGVVGAVGTYALVAINHAPQILPGS
                     IWAGGDLYYASINNTGSYNTDIATKPFYDTPLIGSWRAMAYSPGGVGDIGTACFLAIR
                     IA"
     gene            complement(1190..1816)
                     /locus_tag="ROH59_004871"
     CDS             complement(1190..1816)
                     /locus_tag="ROH59_004871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HDX4807249.1"
                     /translation="MTSQSVLPPNAITPERALEVVLSHVGDLPGDIRIIKNPDLCPAN
                     LLPWLAWEYAVTYWNPDWSEQQKREIIKAAAWQNKHRGTRGAVERALLTVGFESKMRE
                     WFEATPRDDPYTFAIKIYLLKSMGLDLELLNTFIAQIFDAKNCRSLLKEINFETGVDG
                     EFFIAGTPYAKIGVNVPADGDGGVKINGGLYISGSPIVSLNVEIGPNG"
     gene            complement(1819..2739)
                     /locus_tag="ROH59_004872"
     CDS             complement(1819..2739)
                     /locus_tag="ROH59_004872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001729001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDX4807250.1"
                     /translation="MITSTVQNSIVKTIDMSLLPPPAFVKTPLFSDVKSNLLSELQIL
                     YPQFNALLESDPAVKLLEIVAYREIIITARVNQGMLAVLLAFAKGSDLDQIGANFDCL
                     RLLITPANPDVIPPTEAVYESDDEYRHRIQLSWYARNTAGSTNAYNYFALSSDPDVLS
                     AQAYGPPVTQPGYVDMYVLSRTGDGTPPQSLLNTVNAALSPDDTRPLTDFVTVKPASN
                     LNYRVEAVIVAGLGPDQNVLLNGAQSDLAIYVDTQHKIGATAALSGIYDAIHRDGTER
                     VILISPTEDVIAGVGQAPYCTEIKLSVQMG"
     gene            complement(2736..3077)
                     /locus_tag="ROH59_004873"
     CDS             complement(2736..3077)
                     /locus_tag="ROH59_004873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HDX4807251.1"
                     /translation="MLGMDRNTGKLLSGTDHIRQSIVDILTTPLGTRVMLPEYGSKLF
                     DLVDNPTDPSLAMRIIMESAGAIARWEPRVRIDRINVLAVDIGKITILIIATDIETQQ
                     RLEFNNMELIF"
     gene            complement(3080..3982)
                     /locus_tag="ROH59_004874"
     CDS             complement(3080..3982)
                     /locus_tag="ROH59_004874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HDX4807252.1"
                     /translation="MAQSDDEYAAAENARRLRDAVKRGTIAAVKMNPPRCRVSFGGEH
                     QSGWLQWFTHATSERVDWSAPSVGDPVTVVSEGGDTRNGVVMLGLHIDDKAPPSNDPH
                     DHVTAYCDGATMTYNTKNHTLTWQGVPDGVVKILGESEIEIFGRADVTINSENVVNIH
                     GGKLINADADIINVTATDTINAHADLVNVIATSSVSVTAANRISLTAQTISAWAPGGI
                     TLAGPTHITETLVVDKLATFRNDISVTGDNGGTGNITTRGSVLAGQEVQDRQGTITEV
                     RTTYNGHTHICPDGETQQPNQPMA"
     gene            complement(3963..4499)
                     /locus_tag="ROH59_004875"
     CDS             complement(3963..4499)
                     /locus_tag="ROH59_004875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807253.1"
                     /translation="MSGLDAFDEYLDRVKGAVLQIPFIKTFGIYPEIPAGFETPALFL
                     EISNWSQSDESVPGSIQSVELSCNLYLLREFAADQYGLKSQNAALYMTSWINGRMFGP
                     GTKPAKFSDAEPCDWIKNGQSVGSHSVQCVSFTQVVGVGPDIFDYPSQGTLKNIYVGI
                     APDIGAEHEGDYYGPIGR"
     gene            complement(4496..5176)
                     /locus_tag="ROH59_004876"
     CDS             complement(4496..5176)
                     /locus_tag="ROH59_004876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807254.1"
                     /translation="MADLRSNAQMFDIDVSALEQLRVEISATQHQMLMVYNRALNRTA
                     KHMHRISAGMILTALAAKNHKAVDKRIKPFIKRRNFTKEGAGDLSSAKLWYGLNDFRV
                     SELKGRLQNPRRQKQPRDLETGLFLKTKKGARGATFTPKSAGLAMMSWPDSFVAKRYG
                     AKSVWIRLDRGGIEEARVPVHDALEDAIDDYIFENIGPVFMGFFEKDLRGRVKGNVHV
                     DPKTGKRL"
     gene            complement(5208..5588)
                     /locus_tag="ROH59_004877"
     CDS             complement(5208..5588)
                     /locus_tag="ROH59_004877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807255.1"
                     /translation="MSYYDDLRAGDEEMIREWGRPVKLRGKTDPIIAIFNEPYARVDV
                     PHAGFITGTVTSLTALSDDVAGVVARDVVQVPKQRSIEPDGSVTWSGWTDYVVKEPQP
                     DGTGLTNIFLEPHTSSENSEYSKY"
     gene            complement(5585..6004)
                     /locus_tag="ROH59_004878"
     CDS             complement(5585..6004)
                     /locus_tag="ROH59_004878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HDX4807256.1"
                     /translation="MSTKTELLARIDDLSAQLGRELPRSGTIAELESIVAGAESELDI
                     LNEQSGDAGGIEITVNTASGTDNELAQSIASAIVSQSQEQELAPATRRVKLRNTLDVY
                     HYVNGRRVREIVAAGREIVVDSPEVADLIAADHVYAL"
     gene            complement(6039..>6175)
                     /locus_tag="ROH59_004879"
     CDS             complement(6039..>6175)
                     /locus_tag="ROH59_004879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="major capsid protein E"
                     /protein_id="HDX4807257.1"
                     /translation="ISEATRYPKVWTTTGDPAVTQTMTQSAPAMVLTDADAFVVVKIA
                     "
BASE COUNT         1479 a         1599 c         1387 g         1710 t
ORIGIN      
        1 caacgcttat cattacgcaa tcctaatagc taaaaaacag gcagtcccaa tatcaccgac
       61 tccaccgggt gaatacgcca tggctcgcca tgagccaata agtggtgtgt cataaaatgg
      121 ttttgtggca atatccgtgt tatatgaacc ggtattattt atactagcgt aatataaatc
      181 ccctccagcc catatggagc ccgggagtat ttgtggtgca tgattaatag cgacaagcgc
      241 ataagtacca accgcgccaa caacacctat ttccggtgat gggtccggtg aaagacttat
      301 atctatgttg ccattttcat ccggcgactc cccgttaatc gttttaaccg gtttaagatt
      361 agcctcattc cagtatttat acgtctgccc gccgcacagt aacaccaggc catcatagtg
      421 aactccgcgt aatctataaa aaaccttctg attgttttct ccacgggtcg aaaaatctaa
      481 ataatcgccc gacacatctg ataaaccagc aaatgaaaac aacgtcaaat cagtgcccgg
      541 tttgtttata tttatttgtt ttttagagga taaaacgtct tcaaaaatca catcatcttt
      601 aaaagtattt ggatgagtaa atgcattacc cttatctcta tatgcaacgt ccccatctat
      661 accaatattt ttccgcgcag cctgctgagc agtttcacca tttgcgggaa tttcagataa
      721 gtttttactt atctgcaaat attttttgtc agcttcctcg ggagttacgt agttgtcata
      781 tactacaaca ttaaccgtag atgtgctgga caccgcgagt gtgtatttat acgtgattga
      841 aatcagcgca ccgttgctgt ccgtaggttt taaaatgtcc ggcgagcgcg ccacagagta
      901 cagctcgcct ttatctgtta atatccccac ctcacggata gtatagcccc cagtgtctgg
      961 cggtacgtaa agtgtaaaga taacctggtt accgctattt tctgcggatt taatatcccc
     1021 acgatacgtc tcgtgaatta atgcagttcg tgccgggtcc ggtgttacgt cgtcgtttcc
     1081 gtttgcgtcg ccaataacga atttattcag caccacgggt acacccgatg ccagcgcagc
     1141 ggcttcaagt tgtgcgccac ggtctgtcag tactgcgtaa attttatttt cagccatttg
     1201 gccctatctc cacatttaaa ctaacaattg gtgagcccga tatatatagc ccgccgttaa
     1261 tttttacacc gccgtcgccg tctgctggga cgtttacgcc tattttcgcg taaggtgtac
     1321 cggctataaa aaactcacca tcgacacccg tttcgaaatt tatttctttt aataaggaac
     1381 gacaattttt tgcatcaaat atttgtgcaa taaatgtatt caatagttct aaatctaacc
     1441 ccatgctttt tagcagatat attttaattg cgaatgtata cgggtcgtcc ctgggcgtgg
     1501 cttcaaacca ctctctcatt ttgctctcaa agccaacagt taataacgct cgttcaacag
     1561 ctccacgcgt tccgcggtgc ttattctgcc acgcagctgc tttaataatt tcgcgttttt
     1621 gctgctcact ccagtcgggg ttccagtagg tgaccgcgta ctcccacgcc agccacggca
     1681 acagatttgc agggcacaaa tcgggatttt taataattcg aatatcgcca ggcagatcgc
     1741 cgacgtgaga taaaacaacc tcaagcgccc tctcaggggt tattgcgttc ggaggcagta
     1801 cgctttgact tgtcatggct accccatttg cacgctgagt ttgatttctg tgcagtacgg
     1861 agcctgcccg acgccagcga tcacatcctc tgttggcgat atcagaatca cacgttcagt
     1921 gccgtcacga tgtatcgcgt cgtaaattcc tgacagagct gccgtcgctc cgattttatg
     1981 ttgcgtatcc acatatatcg ccaaatcgct ctgagcaccg ttaagcaaaa cgttctggtc
     2041 gggtccgagc ccggctacga taacggcctc aacccggtaa ttcaggttcg acgcaggttt
     2101 tacagtcacg aaatcagtca gcggtcgagt atcgtcagga gacagggccg cattcactgt
     2161 attcagtagt gattgaggcg gagtgccgtc gccggttcgc gacaagacat acatatcgac
     2221 gtatccaggc tgggtcaccg gcgggccgta cgcctgagct gacagaacgt cgggatcact
     2281 cgacagcgcg aaatagttat aggcgttcgt actgccggca gtattccgcg cataccatga
     2341 tagctgtatt cggtgtcgat actcgtcgtc actctcgtaa acagcctcag tcgggggaat
     2401 tacatcggga ttagctggcg ttatcaacag ccgcaggcag tcaaaattag cgccaatctg
     2461 gtcgaggtca ctcccctttg caaacgcgag caatacagcg agcatcccct gatttacccg
     2521 agctgtaata atgatttctc tgtatgcaac tatttccagc agtttaacgg ccgggtctga
     2581 ctccaggagt gcgttaaatt gtggatataa tatctgcagc tctgacagta gattagattt
     2641 aacatctgaa aataacgggg ttttaacgaa tgctggcggc ggcagcagac tcatatcaat
     2701 agttttcact atcgaattct gaactgttga tgttatcaaa atatcagctc catattatta
     2761 aactctaatc gctgttgtgt ttcgatatct gttgcgataa ttaatattgt tattttcccg
     2821 atatccactg ctaacacatt tattctgtca attctgacgc gtggttccca tcgtgctatt
     2881 gcgccagcgc tttccatgat tattcgcata gcaagcgacg gatctgtggg attatcaaca
     2941 agatcaaata atttgctgcc atattccggc agcattacac gcgtccccag cggggtcgtt
     3001 aaaatatcaa cgatagactg acgaatgtga tcagtccccg ataaaagttt accggtgtta
     3061 cggtccattc caagcatctt tacgccattg gttggttcgg ttgttgagtt tccccgtccg
     3121 gacatatatg agtgtgtccg ttatacgttg tgcggacttc agttattgtg ccttgtcggt
     3181 cctgcacctc ttgccctgct aacacactac cgcgagttgt gatattacct gttccaccgt
     3241 tatctccagt gacagaaata tcgttacgga atgtcgctaa tttatctact actaatgtct
     3301 cggtaatatg cgttggacca gctagtgtta taccacccgg agcccacgcg ctgattgttt
     3361 gagctgtcag cgatattctg ttcgcagcag taacactaac agaactcgtt gctataacgt
     3421 tcactaaatc agcatgtgcg ttaattgtat ctgtcgctgt gacattaata atatcagcgt
     3481 ctgcgttaat taatttccca ccatggatat taactacatt ttcgctatta atagtaacat
     3541 ctgcgcgtcc aaatatttct atttcagact caccgagtat ttttaccacg ccgtccggta
     3601 cgccctgcca tgtcagagtg tgattttttg tgttatacgt catcgtagcc ccgtcacagt
     3661 atgcagtgac atgatcatgg gggtcattgc ttggcggagc tttgtcgtca atgtgcagcc
     3721 cgagcataac tacaccgttc cgcgtatccc caccctcaga aacaacagta acgggatcgc
     3781 ccactgatgg tgcgctccag tcgacgcgtt ctgaggtggc gtgagtaaac cactgcagcc
     3841 agcctgactg gtgttcgcca ccaaatgaga ctcggcagcg tggaggattc attttaactg
     3901 cagctatcgt gccgcgttta actgcgtcac gcagcctgcg cgcgttctcc gctgcagcat
     3961 attcatcgtc cgattgggcc ataatagtcg ccctcatgtt ctgcgccgat atctggtgct
     4021 attccgacgt atatattttt cagggtcccc tgtgagggat aatcgaaaat atctggacca
     4081 acgcctacaa cctgcgtgaa cgacacgcac tgaactgaat gcgaaccgac tgactgcccg
     4141 tttttaatcc agtcgcacgg ttccgcgtcg ctgaattttg ccggtttagt tccgggaccg
     4201 aacattcgcc cattgatcca gctcgtcata tagagcgctg cattctgcga tttcagtccg
     4261 tactgatcag ctgcaaattc acgcagcaaa tacaaattac acgacagctc gactgactga
     4321 attgagcctg gaaccgattc gtcactctgt gaccagttgc tgatttccag gaacagagct
     4381 ggcgtttcaa atccagccgg aatttccgga taaattccga atgttttgat gaacggtatt
     4441 tgtaaaaccg cgcctttaac gcgatcaaga tattcgtcaa atgcatccag tccgctcata
     4501 atcgtttacc tgtttttggg tctacgtgga cattaccttt cacgcgaccg cgcaaatctt
     4561 tctcaaaaaa gcccataaaa acagggccaa tgttttcaaa aatataatca tcgatagcat
     4621 cctccagcgc gtcgtgcaca ggtacgcgag cctcttcgat tcctccgcga tccagtcgaa
     4681 tccagacact tttcgcaccg tagcgtttcg ctacgaatga atcgggccaa ctcatcatcg
     4741 ccagccctgc acttttgggt gtaaaagttg cccctctagc gccttttttg gttttcaaaa
     4801 acaggccggt ctcaagatcg cgaggctgtt tttgcctccg tggattttgt aatcgcccct
     4861 ttagctcaga tacccggaaa tcattcagac cgtaccagag cttggcgctg ctcaggtctc
     4921 ctgccccttc ttttgtaaaa ttacggcgct taatgaacgg cttgattcgt ttatctacgg
     4981 ccttatgatt tttagctgcc agtgcagtca aaatcattcc tgctgaaatt cggtgcatat
     5041 gttttgcagt tcggttcagc gccctgttgt ataccattaa catttgatgt tgcgtcgcgc
     5101 tgatttcgac tctgagctgc tccagcgccg aaacatcgat atcgaacatc tgcgcgttac
     5161 tacgtaaatc ggccacggtt cccccttaag tgggaccgag gtcccactta gtattttgaa
     5221 tactcgctgt tttcgctgga cgtgtgaggc tctaaaaaaa tattcgtgag ccctgtgcca
     5281 tcaggttgag gctctttaac cacgtaatcg gtccagccag accaggtaac agagccgtca
     5341 ggttcgatgc tgcgctgctt tggaacctgg acgacgtcac gcgcaacaac gccagcgacg
     5401 tcgtccgaga gcgccgtcag gctcgttact gtaccggtaa taaaaccagc gtgaggaacg
     5461 tcaacgcgcg cgtaaggctc gttgaaaata gcgataatgg ggtcggtttt accgcgtaat
     5521 ttaacgggcc gtccccactc acggatcatc tcctcgtcgc cggcccggag gtcatcgtag
     5581 tagctcatag agcgtaaacg tgatcagctg cgataaggtc tgcgacctcc ggtgaatcaa
     5641 caacaatttc acggcctgcg gcaacaatct cgcgaacgcg acgcccgttc acgtagtgat
     5701 aaacgtccag cgtgttacgc aacttgacgc ggcgcgtagc cggtgcgagc tcctgctctt
     5761 gtgactgtga aacgatagcg ctcgcgattg attgagcgag ttcattatcg gtcccggacg
     5821 cagtattcac tgtaatctcg atgcctcccg cgtcaccgga ttgctcgttc agaatatcga
     5881 gctctgactc agcgccggca acgattgatt ccagttccgc aatagtcccg ctgcgcggta
     5941 attcgcgacc gagctgagcg ctcagatcgt caatacgcgc cagcaattct gtttttgtgc
     6001 tcatgttgat tccttaacaa aaaagagcct ttcgactctt acgcgatttt tacgacaacg
     6061 aacgcgtcgg cgtccgtgag gaccattgct ggcgcggatt gcgtcattgt ttgcgtcact
     6121 gccggatcac cggtagtggt ccagactttt ggatagcgcg tcgcttcgga aatac
//
LOCUS       DAPOXO010000166         6048 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.166, whole genome shotgun sequence.
ACCESSION   DAPOXO010000166 DAPOXO010000000
VERSION     DAPOXO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6048
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.166"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            114..872
                     /locus_tag="ROH59_004880"
     CDS             114..872
                     /locus_tag="ROH59_004880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HDX4807258.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGQTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
     gene            complement(925..1032)
                     /locus_tag="ROH59_004881"
     CDS             complement(925..1032)
                     /locus_tag="ROH59_004881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807259.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(1203..2227)
                     /locus_tag="ROH59_004882"
                     /pseudo
     CDS             complement(1203..2227)
                     /locus_tag="ROH59_004882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
     gene            2751..4679
                     /gene="thrS"
                     /locus_tag="ROH59_004883"
     CDS             2751..4679
                     /gene="thrS"
                     /locus_tag="ROH59_004883"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDX4807260.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSDYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            4683..5225
                     /gene="infC"
                     /locus_tag="ROH59_004884"
     CDS             4683..5225
                     /gene="infC"
                     /locus_tag="ROH59_004884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDX4807261.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            5322..5519
                     /gene="rpmI"
                     /locus_tag="ROH59_004885"
     CDS             5322..5519
                     /gene="rpmI"
                     /locus_tag="ROH59_004885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDX4807262.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            5572..5928
                     /gene="rplT"
                     /locus_tag="ROH59_004886"
     CDS             5572..5928
                     /gene="rplT"
                     /locus_tag="ROH59_004886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDX4807263.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
BASE COUNT         1675 a         1292 c         1461 g         1620 t
ORIGIN      
        1 gttattcgcg cctttttata attcgttacc tttccaggga cgctaatctt tatccttaag
       61 aaagtttccg ggaccgcgat ggtctctttt tttgttgtac ggactcttga taaatgaagc
      121 ttttgaagac agttcctgcc atcgttatgt tggcgggggg catgtttgcg tcactgaatg
      181 cagctgccga tgattccgtt tttactgtca tggacgatcc tgccagcgct aaaaaacctt
      241 tcgaaggtaa tctgaacgca ggatatcttg cacaatcagg caatacgaaa agctcctcac
      301 ttacggctga caccactatg acctggtatg gacaaaccac tgcctggtcg ctgtggggga
      361 acgccagtaa tacttcttct aatgatgagc gttcttcaga aaaatatgcg gcgggcgggc
      421 gtagccgttt taatttaact gattatgact atttatttgg tcaggcaagc tggctgacag
      481 accgttataa cggctatcga gagcgcgatg tgttgaccgc gggttatggt cgccagtttt
      541 tgaatggccc ggtacacagt ttccgctttg aattcggccc tggtgtgcgt tacgacaaat
      601 ataccgacaa tgccagtgaa acccagccgc tgggctatgc ctccggggct tatgcatggc
      661 agttgactga caacgctaaa tttacgcagg gtgtttcggt ctttggcgcg gaagacacaa
      721 cgctgaactc cgaaagcgca ttaaatgttg ctattaatga acattttgga ctgaaggtgg
      781 cttacaacgt tacatggaac tctgaacctc cagagtctgc accggaacat accgatcgtc
      841 ggacaacctt atcgttgggt tacagcatgt aaaattatct gccggaccgt gttatgcggt
      901 ctggctgttt tcgtttgtca ctgctcagcc ccaaatcatt gctgcccaac gtagcaacaa
      961 catagcgcca cagattgcca gtagcaccac caccatcttc cagtgttttt tatcaaagcg
     1021 tttagtcggc ataccagtgt cctgcatatc tcttgtgcgt gataacggag tgtaacaaaa
     1081 gggacaggca tcaagggatt ttttgttatt acagtcgtcg ggtggcgttg tacacctggt
     1141 cactgtttct gcattttatg aaaaaaatta tgtatcgata tacaaatatc ataaatagcg
     1201 ggttataaat acgtctttag ttcatcagca ctaaaactca ggctttggct gattacattt
     1261 atagcagcat aatatgtttc tacagtttta tgatgattat gatgaatggc tatatgaaca
     1321 gctgacatgt tgtcatgatt tttagcggcc aacagtgtaa ataactgacg ttggctaaaa
     1381 gaatattttt ttcaaaagta cccaacgttg atatataaga taacacgaca tctttactta
     1441 ctgacaaagt atgattgtct atatataaaa tcgcggacat atgactgaca ttgtttgcca
     1501 tcattcgaca gaagaaaata tctaaagcaa agccaaaatc ctgactcgcg ataacgcgac
     1561 tccttgcaag aggatggcga agtaatgctc tgaattccgc gtcccggact aagggaacat
     1621 gctgctgtat ggattcaatg gaggagtaat gtttaatcag gttgactttg ccttttccat
     1681 ttctcaatga atcaagggcg tattgtaatg acggatggcg acaaaaaata gtgtcagaag
     1741 gagattgcga aaaaatacac tatcattgag atttactgtt ggctgtatgg ttttttctct
     1801 atgaattttt ttggacagtt tcatgcaatg gttacgtttt tcggcagtta actgttcccg
     1861 ttcaatataa tccagtatgc ttcgcaaatg gttagcttta ataggcgtgg tttccagaaa
     1921 taaggaaatg atttattttt tatagtgtaa tgagtgtatt ttctgcatgg atgggtgaag
     1981 tggcaaagtt aatgataaaa agggcagtgg aataacaatt gtgtgatatt tttcgacagc
     2041 ttacggtaaa ttcctgagta acacagtatg acagcatcga acttaaatca gaggtatcaa
     2101 gtagggtgat gagctggcgc gcaaattgac taataggctc tgatgaaggc gttagtatgt
     2161 cgctatcgat gtgcattcta agaggagact cataatgagt tctgataatg atatcgtttt
     2221 cactcataat ctattcgcct tatatatgtc tggagatttt gaggatgatg attaattatt
     2281 atcgccagaa cgaaatgcgc acgaaaaatt gctataagaa ttgtgtcact tttatcattg
     2341 cgatatgacc acttcgtcac tgaatctcat gatcgtttaa ataccaccgc caaataacgc
     2401 aacgaacttt gctggattca gtttatgctg ctgtaaatcc gctcgtagta aacctttcag
     2461 acactctgtg atgatatcag tggttcttta agcgttttgc tggtgtactc actacaaacg
     2521 aattgcgaat cgaatcaatg tgaaacggaa aggtacaatc tccctttttt tagtgttaac
     2581 atcgttcaac cgggtggaag gtgagaggtt aatgtctttc atttgtgtac ctgattgcga
     2641 accaatttag catttgttgg ctagatggtt tcgcaatgaa ctgttaataa acaaattttt
     2701 ctttgtatgt gatctttcgt gtgggtcacc actgcaaata aggatatata atgcctgtta
     2761 taactcttcc tgatggcagc caacgccatt acgaccacgc tgtaagcccc atggatgttg
     2821 cgctggacat tggtccaggt ctggcgaaag cctgtatcgc agggcgcgtt aatggcgaac
     2881 tggttgatgc ttgcgatctg attgaaaacg acgcacaact gtcgatcatt accgccaaag
     2941 acgaagaagg tctggagatc attcgtcact cctgtgcgca cctgttaggg cacgcgatta
     3001 aacaactttg gccgcatacc aaaatggcaa tcggcccggt tattgacaac ggtttttatt
     3061 acgacgttga tcttgaccgc acgttaaccc aggaagatgt cgaagcactc gagaagcgga
     3121 tgcatgagct tgctgagaaa aactacgacg tcattaagaa gaaagtcagc tggcatgaag
     3181 cgcgtgaaac tttcgccaac cgtggggaga gctacaaagt ctccattctt gacgaaaaca
     3241 tcgcccatga tgacaagcca ggtctgtact tccatgaaga atatgtcgat atgtgccgcg
     3301 gtccgcacgt accgaacatg cgtttctgcc atcatttcaa actaatgaaa acggcagggg
     3361 cttactggcg tggcgacagc aacaacaaaa tgttgcaacg tatttacggt acggcgtggg
     3421 cagacaaaaa agcgcttaac gcttacctgc aacgcctgga agaagccgcg aaacgcgacc
     3481 accgtaaaat cggtaaacag ctcgacctgt accatatgca ggaagaagcg ccgggtatgg
     3541 tattctggca caacgacggc tggaccatct tccgtgaact ggaagtgttt gttcgttcta
     3601 aactgaaaga gtaccagtat caggaagtta aaggtccgtt catgatggac cgtgtcctgt
     3661 gggaaaaaac cggtcactgg gacaactaca aagatgcaat gttcaccacg tcttctgaga
     3721 accgtgaata ctgcattaag ccgatgaact gcccggggca cgtacaaatt ttcaaccagg
     3781 ggctgaagtc ttatcgcgat ctgccgctgc gtatggccga gtttggtagc tgccaccgta
     3841 acgagccgtc aggttcgctg catggcctga tgcgcgtgcg tggttttacc caggatgacg
     3901 cgcatatctt ctgtactgaa gaacaaattc gcgatgaagt taacggatgt atccgtttag
     3961 tctatgatat gtacagcact tttggcttcg agaagatcgt cgtcaaactc tccactcgtc
     4021 ctgaaaaacg tattggcagc gacgaaatgt gggatcgtgc tgaggcggac ctggcggttg
     4081 cgctggaaga aaacaacatc ccgtttgaat atcaactggg tgaaggcgct ttctacggtc
     4141 cgaaaattga atttaccctg tatgactgcc tcgatcgtgc atggcagtgc ggtacagtac
     4201 agctggactt ctccttgccg tctcgtctga gcgcctccta tgtgggcgaa gacaacgagc
     4261 gtaaggttcc ggtaatgatt caccgcgcaa ttctggggtc gatggaacgt ttcatcggta
     4321 tcctgaccga agaattcgct ggtttcttcc cgacctggct tgcgccggtt caggttgtta
     4381 tcatgaatat taccgattca cagtctgatt acgttaacga attgacgcaa aaactatcaa
     4441 atgcgggcat tcgtgttaaa gcagacttga gaaatgagaa gattggcttt aaaatccgcg
     4501 agcacacttt gcgtcgcgtc ccatatatgc tggtctgtgg tgataaagag gtggaatcag
     4561 gcaaagttgc cgttcgcacc cgccgtggta aagacctggg aagcatggac gtaaatgaag
     4621 tgatcgagaa gctgcaacaa gagattcgca gccgcagtct taaacaattg gaggaataag
     4681 gtattaaagg cggaaaacga gttcaaacgg cgcgccctaa ccgtatcaat ggcgaaattc
     4741 gcgcccagga agttcgctta acaggtctgg aaggcgagca gcttggtatt gtgagtctga
     4801 gagaagctct ggagaaagca gaagaagccg gagtagactt agtcgagatc agccctaacg
     4861 ccgagccgcc ggtttgtcgt ataatggatt acggcaaatt cctctatgaa aagagtaagt
     4921 cttctaagga acagaagaaa aagcaaaaag ttatccaggt taaggaaatt aaattccgtc
     4981 ctggtacaga tgaaggcgac tatcaggtaa aactccgcag cctgattcgc tttctcgaag
     5041 agggtgataa agccaaaatc acgctgcgtt tccgcggtcg tgagatggcg caccagcaaa
     5101 tcggtatgga agtgcttaat cgcgtgaaag acgatttgca agaactggca gtggtcgaat
     5161 ccttcccaac gaagatcgaa ggccgccaga tgatcatggt gctcgctcct aagaagaaac
     5221 agtaaggcct tcaagtagca ctgtctgtgg agcctttggg cttcacaggc attgttcgcc
     5281 tttgtttcgt ttattaacaa tgcgaagtgg aagttattaa aatgccaaaa attaagaccg
     5341 tacgcggtgc tgctaagcgc ttcaaaaaaa ccggtaaagg tggttttaag cacaagcacg
     5401 ctaacctgcg tcacattctg accaaaaaag cgaccaaacg taaacgtcac ctgcgtccga
     5461 aagccatggt ttccaaaggc gatctgggcc tggtaatcgc gtgcctgccg tacgcataag
     5521 ccgttaacgt ttttaacttt ttaattagaa tatagataca ggagagcaca tatggctcgc
     5581 gtaaaacgtg gtgttattgc acgcgcacgt cacaagaaaa ttttgaaaca agctaaaggc
     5641 tactacggtg cgcgttctcg cgtataccgc gttgccttcc aggctgttat caaagctggt
     5701 cagtatgctt accgcgaccg tcgtcaacgt aagcgtcagt tccgtcaact gtggattgcg
     5761 cgtatcaacg cagcagcacg tcagaatggt atttcttaca gcaaattcat caatggcctg
     5821 aaaaaagcct ctgttgaaat cgaccgtaag atcctggctg atatcgcagt attcgacaaa
     5881 gtagcgttca ccgctctggt tgaaaaagcg aaagcagctc tggcataagc cagttgaaag
     5941 agggagctag tctccctctt ttcgtttcaa cgccatcaaa acattgactt ttatcgccgt
     6001 agccttttca ataaaggtct tttgaagagt accaaaaggt aacgcaag
//
LOCUS       DAPOXO010000167         6030 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.167, whole genome shotgun sequence.
ACCESSION   DAPOXO010000167 DAPOXO010000000
VERSION     DAPOXO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6030
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.167"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..789
                     /locus_tag="ROH59_004887"
     CDS             <1..789
                     /locus_tag="ROH59_004887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807264.1"
                     /translation="NVCVQRGVQLRSEDDATDDADRTEQVQEKASVEAISLPLLTKMS
                     SERTLAVQAALMQQPDKSLALLAWTLCLNVFDSGAYSKPAQISLECKHYSLTSDAPSG
                     KEGAAFLALMAEKARLAALLPEGWSRDMTTFLSLSQEVLLSLLSFCTACSLNGVQTRE
                     CGRTSRSPLDSLDSAIGFHMRDWWQPTKANFFGHLKKPQIIAALNDAGLSGAARDAEK
                     MKKGDAAEHAEFHMKDNRWVPGWMCSPRPQTDATERADNLADAA"
     gene            842..1276
                     /gene="psiB"
                     /locus_tag="ROH59_004888"
     CDS             842..1276
                     /gene="psiB"
                     /locus_tag="ROH59_004888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HDX4807265.1"
                     /translation="MKTELTLNALQSMNAQEYEEIRAAGSDMRRNLTHEVMREVDAPA
                     NWMMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQLWMLVLVNGGGQPFAVV
                     QVQHIFTPVAISHTLALAATLDAQGYSVNDIIHILMVEGGQA"
     gene            1273..1992
                     /locus_tag="ROH59_004889"
     CDS             1273..1992
                     /locus_tag="ROH59_004889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001584594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HDX4807266.1"
                     /translation="MSARSRALIPLSAEQQAAMQAVAVTEQRRRQGRTLSAWPYATAF
                     FRCLNGSRRISLTDLRFFAPALTKEEFHGNRLLWLAAVDKLIESFGEVCVLPLPSDAG
                     HRLFPSVPFREGERRRQKTTLTEQKYSRQREREAERRELEYQTCFAQAQIDLAFHTPA
                     TVGSWLSRWSGVVEEHDLETIFWGWCGRFPSLSSFDRFFWQEEPLWRLIFEAGEAGRG
                     APVQVRALEQWMIPNKLENVI"
     gene            1989..2585
                     /locus_tag="ROH59_004890"
     CDS             1989..2585
                     /locus_tag="ROH59_004890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000978013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807267.1"
                     /translation="MMKSDEKYQVPAWMRPLLPLLCNTGGNDPEELLNDTETTASANV
                     VRYVLIVAVRSQVDLLQLLYRKGLLRTEIPGGFSPEEAQALLDNLVRSHISKALSGER
                     MAARDRNADLAWIGQQLVDAAWFVRATLEAHGMSVGNESPPAPPETMPDIQTRELVML
                     IKRLASSLKAVKPDSCVVREAQDWLRDRKLVDITDILR"
     gene            3047..3547
                     /locus_tag="ROH59_004891"
     CDS             3047..3547
                     /locus_tag="ROH59_004891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDX4807268.1"
                     /translation="MSVVAPAVYVGTWHKYNCGSIAGRWFDLTTFDDERDFFAACRAL
                     HQDEADPELMFQDYEGFPGNMASECHINWAWVEGFRRARDEGCEEAYRLWVDDTGETD
                     FDTFRDAWWGEADSEEAFAVEFASDTGLLADVPETVALYFDYEAYARDLFLDSFTFID
                     GHVFRR"
     gene            4276..4710
                     /locus_tag="ROH59_004892"
     CDS             4276..4710
                     /locus_tag="ROH59_004892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="post-segregation killing protein PndC"
                     /protein_id="HDX4807269.1"
                     /translation="MTVSSTISVFCRDGVFRTVYCHLHGEPTWNGRILHTHYATGQQA
                     EALVEHGDIRCLGPRCDKPAGHTLQNPVDGVTAYYGRDSGFRMDSEAREYRSFMEAIA
                     TESTEEVRFHYVFIDGYWKVMYRTPEGWKMKALALALRRCPK"
     gene            4804..5070
                     /locus_tag="ROH59_004893"
     CDS             4804..5070
                     /locus_tag="ROH59_004893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807270.1"
                     /translation="MKPSIIFATAEYVKRLREECLRENKPLHRHTRFRRQELAQDEIN
                     PDVLAMSGHIARRCSEQKRVRIPAMKVSEWGHLLRALEIERVCH"
     gene            5247..5636
                     /locus_tag="ROH59_004894"
     CDS             5247..5636
                     /locus_tag="ROH59_004894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CbiX"
                     /protein_id="HDX4807271.1"
                     /translation="MKSCFDTDKAFHMSFDEVTFNADRIRSKLELLSEELMPRCGLVY
                     ELYQRRLSAAIDNFVATLPTEQHLLVLELAREEFDYLSAEEIAEEIRRDSERGYCCHG
                     FERNCCPLGCGDLGDDCCDAADLMEEP"
     gene            5633..>6030
                     /locus_tag="ROH59_004895"
     CDS             5633..>6030
                     /locus_tag="ROH59_004895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDX4807272.1"
                     /translation="MSKKKNTTTPTPHDAVFRSFLANPDVARDFLELHLPAEYRQLCD
                     LSTLKLEPATFVEPDLHQYASDILWSVKTTGGKDGYVYTLIEHQSTENLYMPFRMLRY
                     SVAAMQRHLEQHKTLPLVIPVLFYHGERSP"
BASE COUNT         1261 a         1645 c         1791 g         1333 t
ORIGIN      
        1 aacgtgtgtg tccagcgtgg tgtgcagttg cgcagtgaag atgacgcgac tgatgacgct
       61 gaccgcacgg aacaggtgca ggagaaagcg tcagtggagg caatcagtct gccgttgctg
      121 acgaaaatgt cttccgaacg cacgctggca gtccaggcag cactgatgca gcaaccggac
      181 aaatctcttg cactgttggc atggacgctc tgcctgaatg tgtttgacag cggagcgtac
      241 agtaaaccag cacaaatcag cctggaatgt aaacattatt cgctgaccag cgatgcgccg
      301 tcagggaagg aaggtgccgc attcctggcg ctgatggcag aaaaagcccg tcttgcggcc
      361 ctgttaccgg agggatggtc acgggacatg acgacgttcc tgtcactcag tcaggaggtg
      421 ctgttatccc tgctcagttt ctgcaccgca tgcagcctta acggtgtcca gacccgcgag
      481 tgtggtcgca cgtcacgcag tccgcttgac tcactggata gcgccatcgg ttttcacatg
      541 cgcgactggt ggcagccgac gaaagcaaac ttcttcggac acctgaaaaa gccgcagatt
      601 atcgcagccc tgaatgatgc cggactgtcc ggtgccgcac gggacgcaga gaagatgaag
      661 aaaggcgatg ccgctgaaca tgcagagttc catatgaaag acaaccgctg ggtgcctggc
      721 tggatgtgtt caccacgtcc acagacggat gccactgaac gcgccgataa cctggctgat
      781 gccgcctgat gaacaaccac accgccccgc cggagacggg gcggcagagg gagataccgt
      841 gatgaaaact gaactgacac tgaatgccct gcagtccatg aatgcccaag aatatgaaga
      901 aatccgtgct gcgggaagcg atatgcgccg taatctcact cacgaggtga tgcgtgaagt
      961 ggacgcaccg gctaactgga tgatgaacgg agagtatggc agcgagttcg ggggcttttt
     1021 ccccgtccag gttcgtttca cgccagccca cgaacgtttc cacctggcat tatgttcgcc
     1081 gggagacgtc tctcagctct ggatgctggt tctggtgaat ggtggtggac agcctttcgc
     1141 cgtcgttcag gtgcaacata tcttcacgcc tgtcgcgatc agtcacacgc tggcgcttgc
     1201 cgcgacactg gatgcgcagg gatacagtgt taacgacatc atccatatcc tgatggtaga
     1261 aggaggtcag gcatgagcgc acgttcacgg gcactgatcc ccctcagcgc agaacaacag
     1321 gccgccatgc aggcggtggc tgtcacagaa caacgtcgtc gtcagggacg cacactttca
     1381 gcatggcctt atgccaccgc tttctttcgc tgcctgaatg gcagtcgccg gatttcgctg
     1441 accgatctcc gcttttttgc ccctgcgctg acgaaggagg aatttcatgg caaccgtctc
     1501 ctgtggctgg ctgccgtgga taaactgatt gaaagttttg gggaagtctg tgttcttccc
     1561 ctgccatccg atgcggggca ccgtctgttc ccgtccgtgc cttttcgtga aggtgagcgt
     1621 cgtcgtcaga aaaccacgct gacagagcag aaatacagcc gccagcggga acgtgaggca
     1681 gaacgacggg aactggaata ccagacatgt tttgctcagg cgcagattga ccttgcgttt
     1741 catactcccg ccacggtcgg aagctggttg tcccgctggt ctggtgttgt tgaggagcat
     1801 gatctggaaa cgattttctg ggggtggtgc gggcgttttc catcactgtc atcatttgac
     1861 cggtttttct ggcaggagga accactctgg cggctgattt ttgaagccgg tgaggccggt
     1921 cgtggtgcac cggtacaggt acgtgcactt gagcagtgga tgatcccgaa caagctggag
     1981 aacgtaatat gatgaaatca gacgaaaaat accaggttcc cgcgtggatg cgacctctgt
     2041 tgccgttgct ctgcaacacc ggggggaacg atccggaaga actgctgaat gatacagaaa
     2101 ccactgccag tgcgaatgtt gtccgttatg tactgatagt tgctgtgcgg tcgcaggttg
     2161 atctgctgca gcttctgtac aggaaagggc tgttgcgcac agagatacca ggtggctttt
     2221 caccggaaga agcgcaggca ctcctggata atctggtgcg cagccatatc agcaaggcgc
     2281 tgtcgggcga gcgaatggca gcccgtgaca gaaatgccga tctggcctgg attggacagc
     2341 aactggtcga tgccgcctgg tttgtccgtg ccacactgga agcgcatggg atgagcgtcg
     2401 gaaatgagag tccccctgct ccgccggaga caatgccgga catacagaca cgggaactgg
     2461 tgatgttgat caagcgactg gcatcatcgc tgaaagcggt gaaaccggac agttgtgtgg
     2521 tgcgtgaagc gcaggactgg ctgcgcgaca gaaaacttgt ggatatcaca gatattctcc
     2581 ggtgaaccag gcatgtatat tttacgcagg gacacgccga tcatgatcgt ttcatatcag
     2641 gggtggtctg gaggtcatgc ggcgtgtcct ctgcactcgc cggaataagg aagtcgccgg
     2701 cggctccgct tttacccggc catgcggggc atggccttgt gggttttcag ctctgtggcc
     2761 tcagcgtcgt gtgcgggctg tgccgtgcct ccatcttagc cgggctggca gggatgcaag
     2821 ggtacgcttc gccgctgcgg tcacccggtc cctccttccc gtctgccgtg attttccggt
     2881 cgttcgtccg ctcaggtttc gcggcctcac cctgcaactc ccgtcagccg tgtgcgtcag
     2941 gctgcggctt cccttgcgcc cctgcatccc cgccttatcg cccggctttt atggaggcac
     3001 ggcaccgccc ggtgtcgcag aacatgtgac tatggaggat tcgggaatgt ctgttgttgc
     3061 acctgctgta tacgttggaa cctggcacaa atacaactgt ggaagcatcg ccggacgctg
     3121 gtttgacctg accacgtttg atgatgagcg cgactttttc gccgcctgcc gtgctcttca
     3181 ccaggatgaa gccgatcctg aactgatgtt tcaggattat gagggattcc cggggaatat
     3241 ggcctctgaa tgtcatatca actgggcctg ggttgaaggc ttccgccggg cacgggatga
     3301 aggctgcgaa gaggcttatc gtctctgggt ggatgatacc ggtgagacgg attttgacac
     3361 cttccgcgat gcctggtggg gcgaggctga cagtgaggag gcttttgcgg ttgagttcgc
     3421 cagtgatacc ggcctgctgg ctgacgtgcc ggagacggtg gcgctctatt ttgactatga
     3481 ggcgtatgcg cgggatttat tcctggactc cttcaccttt attgacggtc atgtgttccg
     3541 tcggtgattt actcccccgc tccggcgggg gtatggcctg ccaggccgcc ggaaaaccct
     3601 ggcaggctta cgcctgcctg aaatgcagga gggccgcgcc tgcggcgctg cccttcctgc
     3661 ccgtcatggt gtgaggcatt tttctgttat gtcgtttctg ttgttctgat ttccggaggc
     3721 ggggacacct tcggctcccg gctgcctggc ggcatccggt cgtcaggccc gactccgaca
     3781 ggcagctgct ggcgcacccg ccagtctccg ccgaacccgc tggcgcggtt tcgggctgcc
     3841 gctacggtcc gatgtctgaa aaaccaggct tgcagcgacc gttccggtcg cgccgcccct
     3901 gtcgcgccgg aaacggcgct ccctgcacac ctgacggtgt gtaaggcaac tgcgcctgat
     3961 ggcgcagcca acccttccgc cgccacccct gcggcctgtt tcccgctgtg gactttccgg
     4021 gggctggagt aaccacatcc cgtttcagca gtccagggga agatataccg tccacaaaat
     4081 ttttagccat aaacccggca aaaaattttg cgtccgcccc cggacagctg ccccgtgacg
     4141 tggtgacgga cgccccatcg gaaaggtcca ctgcggggag aaaccccgaa gaagtggacg
     4201 gcagaagggg ctttcgcccc tccggggagc aaccggtcgg cccggcgacc tgattcagca
     4261 gaaggagacg ttttcatgac agtcagcagc acgatttccg ttttttgccg cgacggggtg
     4321 ttccgtaccg tttactgcca cctgcacggt gagccgacct ggaacggtcg catcctgcat
     4381 acccactatg ccactggtca gcaggccgaa gccctggttg aacacggtga tatccgttgc
     4441 ctcggtcccc gttgcgacaa acccgccggg catacgcttc agaacccggt ggacggtgtg
     4501 acggcttatt acggacgtga cagtggtttc cggatggaca gtgaggcgcg tgagtaccgt
     4561 tctttcatgg aggctattgc cactgaaagc actgaagagg tgcgcttcca ttatgtgttc
     4621 atcgacggct actggaaggt gatgtatcgc acgccggaag gctggaagat gaaagcgctc
     4681 gcgctggcac tgcgccgctg tccgaaatga aaaaaaggca gggcgataaa ccctgcctct
     4741 ctccgccggc gcttccccgc caggaagccc ggcatctcaa tcactatcta tggagattat
     4801 gccatgaaac catcaattat cttcgcaacc gccgagtatg taaagcgtct gcgtgaagag
     4861 tgcctgcggg agaataaacc cctgcaccgc catacccgct tcagacgtca ggagctggca
     4921 caggatgaga ttaacccgga cgtcctggcg atgagcggtc atatcgccag acgctgcagt
     4981 gagcagaagc gggtacgtat ccccgccatg aaagtcagcg aatggggcca cctgctccgc
     5041 gcgcttgaaa ttgaacgggt ctgtcactga ttaacccctg ccgtctgcct gtgcaggtgg
     5101 caggatgtgt tcaggtactt taccaggagg aaccgtgagc aagatgaaaa acatcacgac
     5161 gtctgtgttg catggtgtct ccacaaaaaa cagaaaaggg aaacagattc tctttcattc
     5221 agggcccggg agggctggag ataacaatga agtcttgttt tgatactgac aaagcttttc
     5281 atatgtcttt tgatgaagtc actttcaacg ctgacagaat tcgctcaaaa ctggaactat
     5341 tatccgaaga actaatgccc cgttgtggtc ttgtttatga gctatatcag cgacgtttga
     5401 gtgctgctat tgataatttt gtggccacat tgccgacaga acaacatcta ctggtcctgg
     5461 aactggcccg tgaggagttt gattaccttt ccgcagaaga gattgctgaa gaaatacgcc
     5521 gtgactcaga acgcggctat tgttgtcatg gctttgaacg caattgctgt cctctcggtt
     5581 gtggggattt gggcgatgat tgctgcgatg ctgctgattt gatggaggaa ccgtgagtaa
     5641 gaagaaaaac accacgacgc ccacgccgca tgatgccgtg ttccggtcgt tcctggcgaa
     5701 tcccgacgtc gccagagatt ttctggaact gcatcttcct gcggagtacc ggcagttgtg
     5761 cgacctgtcc acgctgaagc tggaacccgc cacctttgta gagccggacc tgcatcagta
     5821 cgccagcgat atcctctgga gcgtgaaaac caccgggggt aaagacggct atgtttatac
     5881 gctcatcgag caccagagca ccgaaaatct gtacatgcct ttccgcatgt tacgttacag
     5941 tgtggcggcg atgcagagac atctggagca gcacaaaacg ttgccactgg tgattccggt
     6001 gctgttctat catggtgagc gcagcccgta
//
LOCUS       DAPOXO010000168         5980 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.168, whole genome shotgun sequence.
ACCESSION   DAPOXO010000168 DAPOXO010000000
VERSION     DAPOXO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5980
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.168"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..805
                     /locus_tag="ROH59_004896"
     CDS             <1..805
                     /locus_tag="ROH59_004896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX4807273.1"
                     /translation="TSPDFMDLAVETRKDYTKYSGKVLPVFGKIDPDKIKPEHIRRYM
                     DQRGLSSRTQANREKSFMSRVFRWGYERGYVQRNPCQGVKQFKEKARERYITDEEYQA
                     VYEVSPDVVRVAMEIAYLCVARQSDVLSLQKDQLFDSGIYIRQGKTGVKQIKAWSPRL
                     QKAIALARSLPLKTGISSLFVIHQTTGGKYTRDGFNSRWRDVKAAAQEKYPHLQIDFT
                     FHDLKAKGISDLEGSLEEKQAISGHKNPRQTAAYDRKVKVVPVVGGQRK"
     gene            complement(936..1022)
                     /locus_tag="ROH59_004897"
     tRNA            complement(936..1022)
                     /locus_tag="ROH59_004897"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(986..988),aa:Leu,seq:taa)
     gene            complement(1035..1108)
                     /locus_tag="ROH59_004898"
     tRNA            complement(1035..1108)
                     /locus_tag="ROH59_004898"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1074..1076),aa:Cys,seq:gca)
     gene            complement(1162..1237)
                     /locus_tag="ROH59_004899"
     tRNA            complement(1162..1237)
                     /locus_tag="ROH59_004899"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1202..1204),aa:Gly,seq:gcc)
     gene            complement(1389..1937)
                     /gene="pgsA"
                     /locus_tag="ROH59_004900"
     CDS             complement(1389..1937)
                     /gene="pgsA"
                     /locus_tag="ROH59_004900"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDX4807274.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARADLLDQ"
     gene            complement(1994..3826)
                     /gene="uvrC"
                     /locus_tag="ROH59_004901"
     CDS             complement(1994..3826)
                     /gene="uvrC"
                     /locus_tag="ROH59_004901"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDX4807275.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(3823..4479)
                     /gene="uvrY"
                     /locus_tag="ROH59_004902"
     CDS             complement(3823..4479)
                     /gene="uvrY"
                     /locus_tag="ROH59_004902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HDX4807276.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     ANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            4775..4951
                     /locus_tag="ROH59_004903"
     CDS             4775..4951
                     /locus_tag="ROH59_004903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807277.1"
                     /translation="MIKIFIGHYINVFYSTVDITLKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            4938..5162
                     /locus_tag="ROH59_004904"
     CDS             4938..5162
                     /locus_tag="ROH59_004904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HDX4807278.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAMGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQAYRQ"
     gene            complement(5230..5952)
                     /gene="sdiA"
                     /locus_tag="ROH59_004905"
     CDS             complement(5230..5952)
                     /gene="sdiA"
                     /locus_tag="ROH59_004905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HDX4807279.1"
                     /translation="MQDTDFFSWLRTMLLRFQRMEAAEEVYHEIELQAQQLEYDYYSL
                     CVRHPVPFTRPKVAFYTNYPESWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSE
                     AQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRCSTREIPILSDELQLKMQLLVRE
                     SLMALMRLNDEIVMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNM
                     QKKINAPNKTQVACYAAATGLI"
BASE COUNT         1596 a         1509 c         1382 g         1493 t
ORIGIN      
        1 gacctcccct gattttatgg atttggcagt cgaaacccgg aaagactaca caaaatattc
       61 cggaaaagtt ctgcctgtct tcgggaagat cgacccggat aaaatcaaac ctgaacatat
      121 tcggcgctat atggatcaac gcggtttatc aagccgaact caggcaaaca gggaaaaaag
      181 ctttatgtcc cgggtattcc gttggggtta tgaacgaggt tatgttcaga ggaatccttg
      241 tcagggagtt aaacagttta aagagaaagc tcgcgaacgt tatattacgg atgaagaata
      301 tcaggccgtt tatgaagtgt ctcctgatgt tgttcgcgta gcaatggaga ttgcctactt
      361 atgcgtggcc agacagagtg atgtactttc attgcagaaa gaccagctgt tcgattccgg
      421 gatctacatt cgtcagggaa aaaccggcgt taagcaaatc aaagcctggt cgcctcgtct
      481 gcagaaagcg atagctctgg ctcgttctct gccattaaaa acgggaatca gtagcctgtt
      541 tgtgattcat caaactaccg gtggcaagta tacccgtgat ggttttaact ctcgttggcg
      601 tgatgtcaaa gcggcagcac aggaaaaata tcctcatctg caaatagact tcacatttca
      661 tgatctgaaa gcaaaaggta tctctgatct ggaaggcagc ctggaagaga agcaagcaat
      721 ttccgggcat aagaacccgc gacagacagc agcatatgac cggaaagtta aagtagtgcc
      781 cgtagttggt ggccagagaa aatgaatgat gatgcgtcca gagaaaaatc atcttcggac
      841 gcatcttcgg aaatgagaaa gaagatacaa aaaaaccacc cgaaggtggt ttcacgacac
      901 tgcttattgc tttgatttta ttcttatctt tcccatggta cccggagcgg gacttgaacc
      961 cgcacagcgc gaacgccgag ggattttaaa tcccttgtgt ctaccgattc caccatccgg
     1021 gctcgggaaa aaagtggagg cgcgttccgg agtcgaaccg gactagacgg atttgcaatc
     1081 cgctacataa ccgctttgtt aacgcgccaa attcttcagg cctttcagcc agacatccgc
     1141 tgacgccgat gccttttaaa ctggagcggg aaacgagact cgaactcgcg accccgacct
     1201 tggcaaggtc gtgctctacc aactgagcta ttcccgcatt catcaagcaa tcagttaatc
     1261 acttgatttt attatcgtct ggcaatcagt gccgccgttc gatgcgttgc attctactta
     1321 cctggcgcga tgagtcaacg atatttttca ccacttttga tcgtttgctg aaaattgcgc
     1381 cgaaacgatc actgatcaag caaatctgca cgcgcagcgc tcaaatattg caacattgac
     1441 cacagagtca gtaccgcagc cacaaagaaa agtgcaatac cggcgtactc aacccaaata
     1501 ttcggacgcc acagcagcca tgccaacgcc accatctggg cagtggtttt cacttttcca
     1561 atccaggaga cagccacgct actgcgttta cccaactccg ccatccattc gcgtagcgca
     1621 gaaataataa tttcacgggc gatcatcgtt gctgccggta aggtcaccca ccagctgtgg
     1681 taatgctcgg ttaccagcac catggcgata gccacgagaa ctttatctgc gacagggtca
     1741 aggaaagcac caaaccgggt actctgattc cagcggcgtg ccagaaaacc atcgaaccag
     1801 tcagtcaccg ccgcgacgca gaaaatgagc gcggcggcaa acggcgacca ggtgacaggc
     1861 aaataaaaga ccaatacaaa gaatgggata aggatgacac ggaacagtgt aagcaacgta
     1921 gggatattaa attgcataat gacgggtaac tatctgttgt cagtaagatt acccctatgt
     1981 tgctacagag acatcaatgt ttcaacgacc agaagatctt ttctgccaga ccttgcgaaa
     2041 tacccggcac ttttgcaatt tcctcgacgc tggcgttacg taaaccttgc aaaccgccca
     2101 tatatttcaa caacatttgc cgacgttttg gcccgacgcc ttcaatggtt tccagggaac
     2161 tggtattttt gaccttcgcc cgttttttac ggtgcccgcc aatcgcgtga tcgtgtgatt
     2221 catcgcgaat atgctggata acatgcagcg cgggagaatc tggcggcaaa ctaaatccct
     2281 caccttccgg ctcaaagaac agcgtttcca gcccagcctt acgatctgct cctttggcaa
     2341 cgccaagtag cagcggatga tttttatccc atgagacatc cagttcggcg aaaacatttt
     2401 tcgcctgcgc aagctggcct ttgccgccgt caataaggat cacatccggg atcttactgt
     2461 cgtcgatagc tttaccataa cgccgacgca gcacctgatt catcgccgcg taatcatcgc
     2521 ccggcgtgat gccagtaatg ttatagcgcc gatactccgc acgcagcggg ccgttggcat
     2581 caaacaccac acaggaagcg acggtttgtt cacccatggt atggctgatg tcaaagcact
     2641 ccatccgctt cacttccggc aatttcaaca cgctggcaag cgcggtcagc cgctggtgaa
     2701 cggtagattg ctgcgaaagt ttgctggtta aggccgtcgc cgcattggta cgcgcgagtt
     2761 tcagataacg cgctctatcg ccacgaggtt tggtttgaac attaatcttg cgtcccgcca
     2821 gttctgaaag ggaatcggcg agcagcgttt tatcgctaag attaaaatcg agcaggatct
     2881 cacccggtaa ggtgcgcatc tggctgcctt gtaaatagaa ctgacctacg aaggtttcca
     2941 ccacctcgct cagttccgta ccgccaggca ctttcgggaa atagctgcgg ctgccgagca
     3001 ctttgccctg acgaatgaac aatacgtgga cacaagccat acccgcatcg aacgccactc
     3061 caataacgtc aaggtcgtcg ccggtattgg aaacaaactg tttttcggtg acacgtcgca
     3121 ccgcctgaat ttggtcgcga atccgcgccg cttcttcaaa ctccagattc tggctggcag
     3181 tttccatacg actaatgagt tgcgtaagca cctgatcatc tttgccagac aaaaacaggc
     3241 gcacatactc gacctgctga gcgtattctt cttcactcac cagtccttca acgcacggcc
     3301 ccagacagcg ccctatctga tattgcagac acggacgcga gcggttgcga taaacactgt
     3361 tttcgcactg gcgaatgggg aaaatctttt gcagtagcgc cagtgtttca cgtacggcat
     3421 agccattcgg gaacgggccg aaatattcac ctttggcatg cttcgctcca cgatgcatcg
     3481 ccagacgcgg gtgggtatcg ccactcagga agataaaagg atatgattta tcatcgcgta
     3541 gcaaaacgtt gtaacgcggc tgataaagtt tgatgtagtt gtgttccagt aacagcgctt
     3601 cggtttctgt atgagtaacc gttacatcaa tttgctggat ctgggcgacc agcgcttcgg
     3661 ttttgcgcga agcgaggttg ctacggaaat agctggaaag ccgttttttc aggtctttcg
     3721 ctttgccgac atagataacc gtaccaccag catcatacat gcgataaacg cctggctggc
     3781 tggttacggt ttttaaaaac gcttttgcgt caaactgatc actcactgac ttgataatgt
     3841 ctccgcatta cacagaccat ggcgaattgc caggtgagtc agctcaacat cgccatgaat
     3901 gtttagttta ctgaacatac gatagcggta gctgttcacc gttttcggac tgagattgag
     3961 ctgttctgag atctcattga ccttctggcc cttggtgatc atcagcataa tctgcaattc
     4021 acgttcagac aaactggcaa atgggctttc tgttttttct ggttcgatct ggcttaacgc
     4081 catttgttga gcgatatcag aagcaatgta acgctgccct gaatagacag aacgaatcgc
     4141 actcacgact tcctgcggag ccgcgccttt gctgaggtag cccgcagctc cggcctgcat
     4201 gactttcgct ggtaaagggt tttctgtatg gacggtaagc atgatgattt tgacatcagc
     4261 tgtggaacgc gcgattttac gcgtcgcctc aagaccgcca atgcccggca tactcatgtc
     4321 cattagcacc acgtcaacgg catttgcccg gcaccattta acggcgtctt caccgcacga
     4381 tgcctcaccg acgactttta taccctttat atcttccaga atgcgtcgta tccctgcgcg
     4441 caccagttcg tggtcatcaa caagtagaac gttgatcaaa ggaatatctc cagaaatagg
     4501 gataacgcta ctgatagtta gtcattcgta tattagcggt ttttattgca actttgaaac
     4561 gttaaaaatg gtgggtattc gatttttctc tcgtttttgt caattcgatt gtccacagtt
     4621 atggtcacgc ccgtcaccaa cggcttccgg gatcgtttca cagtaagccc ggcgatgaaa
     4681 tgtgacaaaa attgacttta ttcagcaaaa atgaaaatca gcccgctgaa tatgtaacat
     4741 taattaaccc gaacaatacg ggcaaaaaac attcatgata aaaatattta ttggtcatta
     4801 tattaacgta ttttatagta ctgttgatat cacgctcaaa aaacaaccac tgctattttt
     4861 agcaaagctt atggtatact ccgccgcctt aacatttttc accgcaaatt ttcattgcaa
     4921 catgacgagg aaaataaatg agtacgcctg atttttctac tgccgagaat aatcaagaac
     4981 tggcaaatga agtctcctgc ctgaaagcga tgctgacgct gatgctgcag gcgatgggac
     5041 aagctgacgc gggccgcgtg atgttaaaga tggaaaaaca gcttgcgctg atcgaagacg
     5101 aaacccaggc tgcagtattt tccaaaacgg ttaagcaaat taaacaagcc taccgtcagt
     5161 aatataaaac cggctgagag cgtgcctttc agccggtttt tgcatctggc acgcagaaca
     5221 gaaaagagat caaattaagc cagtagcggc cgcgtaacag gcaacctgcg tcttattcgg
     5281 tgcattgatt tttttctgca tgtttttctg atggaaattg accgtattct cagagattga
     5341 caaaatcatc gctatctctg ctgatgtctt accttccgcc gtccatttca gaatttcttt
     5401 ttcgcgcttg ctgaaattca tctctggcgt catcactatt tcatcattta aacgcatcag
     5461 agccatcaga ctttcgcgca ccagtagctg catttttaat tgcagttcat cactaagaat
     5521 gggtatttcg cgcgtgctgc aacgggaaaa ggacaaaaag cccaacgccc gatttggcag
     5581 cattaaatac tgagtgacac cgcggcgtaa accatgtgcg cgcgcagctt cccataacgg
     5641 ctgtgcttcg ctgaataagt catcattcca cattaaatgg ccctgactaa agttttcagg
     5701 gttcagcacc ggatcaattg cgagaaaatt ttttgcctga taataactaa cccacgactc
     5761 agggtaattg gtgtagaaag ccactttagg tcgcgtgaat ggtaccgggt ggcgaacaca
     5821 taacgaatag taatcgtact ccagctgctg agcctgaagc tctatttcat ggtagacctc
     5881 ttctgcggcc tccatcctct gaaaacgcaa cagcatcgtg cgaagccagc tgaaaaaatc
     5941 cgtatcctgc atagtaaacc gcaacgcccc tgagagtgag
//
LOCUS       DAPOXO010000169         5800 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.169, whole genome shotgun sequence.
ACCESSION   DAPOXO010000169 DAPOXO010000000
VERSION     DAPOXO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5800
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.169"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(91..297)
                     /locus_tag="ROH59_004906"
     CDS             complement(91..297)
                     /locus_tag="ROH59_004906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007877521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDX4807280.1"
                     /translation="MERKAIEQILAKQPVMQVNVKIAAVSKYGDHQVEIRCKDTDRLI
                     WRAWDFEKDFKEDLERELLRLAPL"
     gene            complement(368..727)
                     /locus_tag="ROH59_004907"
     CDS             complement(368..727)
                     /locus_tag="ROH59_004907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019706033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807281.1"
                     /translation="MSKGNKMLINRIAVIGLAVVAAATQAAAPPVKFFYRDTVPVSIT
                     LDEPATGCSMAGVIVHPLDRPAAKVAWFSERICGKKRYPVSFISDEISAPDNVIHKGE
                     TFHVTPAQVNLLDAQSL"
     gene            complement(720..1022)
                     /locus_tag="ROH59_004908"
     CDS             complement(720..1022)
                     /locus_tag="ROH59_004908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020314977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CbiX"
                     /protein_id="HDX4807282.1"
                     /translation="MHFTNFLQRYFDIEIEHTFDPTIQGSNETGKDVTKIWIYEKGED
                     SEPLLILTEAWWYTETKTAGNWLIGNVYSTLEHGREIHESEFRKLVTAGKVISQHE"
     gene            complement(1661..1885)
                     /locus_tag="ROH59_004909"
     CDS             complement(1661..1885)
                     /locus_tag="ROH59_004909"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807283.1"
                     /translation="MKGSTKDKLSLAWLIVCIAISVGAGMVYWHYYQPGEGASIKSAY
                     ITWLSAFAVTGCTATILFCISGIARAFKNL"
     gene            complement(1897..2151)
                     /locus_tag="ROH59_004910"
     CDS             complement(1897..2151)
                     /locus_tag="ROH59_004910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CbiX"
                     /protein_id="HDX4807284.1"
                     /translation="MLNKTENNTNISSFNPCSTEGLIAVKDDKGRTHIIQRELISHTE
                     DRSDIEGQAATSVFLVSGKWIRVFLSSEKLARKLGITVSE"
     gene            complement(2161..2877)
                     /locus_tag="ROH59_004911"
     CDS             complement(2161..2877)
                     /locus_tag="ROH59_004911"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807285.1"
                     /translation="MKKLMVVPLLCGLLFGCDNKAEQFQFEAASKAALSAPDPFLALK
                     QFDKQAGDYGKDCGESLGEVIFGVSAGRRAACEKRLEMQTKIVVASVDKGSMPAFMFL
                     LDSGPKYPPVYLTDMPADYANRQRARLFELARSLPPAKENAELFRRAAEDLQTGNNVM
                     QDSTAAIALYKKAWQAGDKSAADELSDVYAFLGDTPRAYFWKIRAHSNPEYTKDVNKL
                     APEEKVVIQRKAADVTQTDI"
     gene            complement(2881..3240)
                     /locus_tag="ROH59_004912"
     CDS             complement(2881..3240)
                     /locus_tag="ROH59_004912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011867776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdR"
                     /protein_id="HDX4807286.1"
                     /translation="MLLELLMFDYRNSDQERYGQQIYHHYRKQGNHRWDTSVHQDSGG
                     QYAIIFRHSFSKKQADGVKRTMIRDETVIRAGTAQELTEATFPAFQDSDILKASDFFK
                     SLNRSDKNTGPEDNEQG"
     gene            complement(3349..3774)
                     /locus_tag="ROH59_004913"
     CDS             complement(3349..3774)
                     /locus_tag="ROH59_004913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX4807287.1"
                     /translation="METIEITARYISENARMNFMPAAFRGAFFSADHFIQSFLNRYAK
                     DYQGGYWEYLQASNGAFFMEAPQPLWLSLPNYFEGECSAREVGIIVCLYAYSYFCGLA
                     YEEGKAELNETMANRYHLLREYVNTLENESQNRIYRAID"
     gene            complement(3926..5203)
                     /locus_tag="ROH59_004914"
     CDS             complement(3926..5203)
                     /locus_tag="ROH59_004914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DGQHR domain-containing protein"
                     /protein_id="HDX4807288.1"
                     /translation="MHTDNYVFELPATRGVQGGVEQYMLTVPMAVLRRLLAMDDQGDV
                     MARSQREANRTRARKIRNYVAEATGSGKPYILPSITGNIDIDVDFFPSELSPSVGILK
                     IPMEADLKLFDGQHRALGIMDFVRDYANTGDTISLLLTVGLPLEMRQQFFADINNNAS
                     KPAAAISMAYNNNDPVNQLAMYLAQNVTGLAGSVDFEHNAVPAKSSRLISFKALNDAT
                     KKMLSLRASSEPTLQQREAAEKLWSAWSGAMRWLDIAQDDIAAEYRQEALGLHGIMIN
                     AMGMATARMLQTRPIDSIVSLLACAEQGENGFHYRDSFMHENWHDICVDPQTGTIRTD
                     RRALEATAKELQRLVDPFAECAWLRPYLGDEVPDTTLLKFNAGIVKLKEETSLPQIAI
                     IEKLEQLRDGDEQTRSRIVGTLRAFKKYIADGV"
     gene            complement(5256..5633)
                     /locus_tag="ROH59_004915"
     CDS             complement(5256..5633)
                     /locus_tag="ROH59_004915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807289.1"
                     /translation="MRVLTPHQFFNLNWYVSNPELTSLKPAQDNEPALAMGYVWFHVQ
                     DEVNGAEPDEDMMCAVFPWYAEITTTDGTPDIQVFTEQDDCWLSAHQFMFARNAVPSH
                     DEYLVYFDSLNWRADVKKLLLDR"
BASE COUNT         1313 a         1562 c         1474 g         1451 t
ORIGIN      
        1 cgcggccggt tacgggggac accgcaccga cacggccagc cataaaaaaa gcgcccatat
       61 gggcgccatt tttcatacta gggcagtgga ttaaagcggt gcaaggcgca gaagttcacg
      121 ctctaaatct tccttaaaat ccttctcaaa atcccaggca cgccagataa gccggtctgt
      181 atctttgcaa cggatttcaa cctgatgatc gccatatttg gaaactgccg ctattttcac
      241 gttaacctgc attaccggct gcttagccag gatttgctct atagcttttc tttccattcc
      301 catgctcctt taatactgcc gataccggcg attattcggg tggcggtatt gccacccgat
      361 gatttaatta gaggctttgc gcgtccagga gattgacctg agccggggta acgtgaaacg
      421 tttccccttt atggatcacg ttatccgggg cgctaatttc atcactgata aagctaaccg
      481 ggtaacgttt tttaccgcaa atccgctcgc taaaccacgc cacttttgcc gctggccgat
      541 ccagtggatg aacaatcaca ccggccatgc tgcaacccgt tgcgggttcg tccagcgtta
      601 tgcttaccgg gactgtatcc cggtaaaaaa acttaaccgg cggcgcggct gcctgcgttg
      661 cggctgcgac aactgcaagc ccgataaccg ctatccgatt aataagcatt ttattcccct
      721 tactcatgct gacttatcac cttgccagct gttaccagtt tacgaaattc gctttcatga
      781 atttcacgcc catgctcaag cgttgaatac acgttgccga taagccagtt accagccgtt
      841 tttgtctcgg tataccacca tgcttctgtc agaataagca gcggttcgct atcctcgccc
      901 ttctcataga tccagatttt agtgacgtct ttacccgttt cgttgctgcc ctgaatggta
      961 gggtcaaagg tatgttcaat ctctatatcg aagtaacgct gaaggaagtt agtaaagtgc
     1021 atgacgactc ctgtttgcgc cgataccggc aatttagcgg gtggcggtgt tgcctcccga
     1081 tgatttaatt atcggtgatt acgcctttaa agtcaataca agtacggaat atatttacct
     1141 gtttttatgc ccgtcagggc atggaaggcg accgcgccgg actccaccgg acaccggccg
     1201 caaatcgccg gaaactgcgg gactgaccgg agcaacaggc caacccccct ccctgctaag
     1261 ccatagccca gcccgccacc acgcagctgc cgcacgtccc ccacgggggt gcgcagtggg
     1321 cgccgcgcgc ctgcgcgcgg gaacggcggc ccgcctgcgg gtcgcggcgc cgtactgcga
     1381 gttagcggcc gccatgcggc cggttacggg ggacaccgca ccgacacggc cagcgccccg
     1441 ctgagctgcg caatccacgg ataatgcagg agacgaatca ggataggagg ctgaagggga
     1501 aatgagcggc agctggggaa ggggttgcca agcgaagcgc ggaggccgca ggccggaggc
     1561 gtcagtggca gctgcccgcg tgagcggggc gagacgcgta gcggctcgat gcgcagcaca
     1621 gcagaacggc cccggagggg tgacgtccgg ggttccgctt ttaaagattt ttaaacgctc
     1681 tggcgatacc gctgatgcag aataaaattg ttgctgtaca gcctgtcact gcaaaagcgg
     1741 aaagccaggt aatgtatgcg ctcttgatac ttgcgccttc accgggctga taataatgcc
     1801 agtacaccat accggcgccc actgatatag ctatgcagac aatcagccag gctaatgaca
     1861 gcttatcttt tgttgaacct ttcattcttt accccgttat tcagacacgg taatgccgag
     1921 ttttcttgcc agtttttcac tagataaaaa tacccttatc cacttcccgg acactaagaa
     1981 aacggacgtc gctgcttgcc cttcaatatc agatctgtcc tctgtgtggg atattaattc
     2041 acgctggatg atgtgcgtcc ggcctttatc atcctttacg gcgattaaac cctctgtaga
     2101 acagggattg aagctactaa tgttggtgtt gttttcggtt ttgttcagca tggctgaccc
     2161 tcaaatatcg gtttgtgtta cgtctgccgc tttgcgctgg ataactacct tttcctccgg
     2221 cgccagcttg ttcacgtcct tcgtgtattc agggttgctg tgagcgcgaa ttttccagaa
     2281 ataagctcgc ggcgtgtcgc ccagaaacgc atagacatca gacagttcat ctgcggccga
     2341 tttatcgcct gcttgccagg cctttttata aagagcaatg gctgccgtgg aatcctgcat
     2401 cacgttattt cctgtttgca gatcttcagc tgcgcggcgg aaaagctctg cattttcctt
     2461 tgccggtggc aacgatcgag ccagctcaaa caggcgcgcc ctttgccggt tagcatagtc
     2521 agcaggcata tcagtcaggt agacaggcgg atatttaggg ccactatcga gaaggaacat
     2581 gaaagcaggc atggaacctt tatcgaccga agcaacaact attttggtct gcatttctaa
     2641 tcgcttttcg caggcagcac ggcggccagc tgatacgcca aatatcactt ccccgaggga
     2701 ttcgccacaa tctttaccat agtctccggc ctgtttatca aactgcttga gagccagaaa
     2761 cggatcgggc gcgctcagcg ctgctttgct ggccgcttca aactgaaact gttcggcttt
     2821 gttgtcgcaa ccgaaaagca ggccgcaaag tagcgggaca accatcagct ttttcatgtt
     2881 tcatccttgc tcgttatctt ccgggccggt gtttttatcg cttcggttaa gcgacttaaa
     2941 gaaatccgac gccttcagaa tatcgctatc ctggaaggca ggaaatgtcg cttccgtcag
     3001 ctcctgcgcc gtacctgccc gtataacggt ttcatcgcgg atcatcgttc gcttaacgcc
     3061 atcagcctgt tttttgctga aggagtgccg gaaaataatc gcgtactggc cgccactatc
     3121 ctgatgaaca gaagtatccc agcgatgatt accctgttta cgatagtggt gatagatttg
     3181 ctggccgtag cgctcctgat cggaattacg gtaatcgaac attaacagtt ccaaaagcat
     3241 taaccgagct ggcaattgcc aggcggtagg gtgttgaagt gtcgctaaca tagtttctcc
     3301 tgagcgtgac agtcacgata aggcgggctt tgcccgcctg gttatcagtt aatcaatggc
     3361 acgataaata cgattctggc tttcgttctc cagcgtatta acgtactccc gcaacaggtg
     3421 ataccggtta gccatcgttt cgttcagttc ggctttgcct tcttcatatg ccagcccgca
     3481 aaagtaactg taggcataca gacaaacaat aatccctact tcgcgcgcgc tgcattcacc
     3541 ttcaaaatag ttaggcaacg agagccaaag aggttggggc gcttccataa aaaatgcgcc
     3601 attgctggcc tgaaggtatt cccaataccc tccctggtag tctttagcgt aacgattcag
     3661 aaaggactga atgaagtgat cagcgctgaa gaaagcgcca cgaaaggccg ctggcatgaa
     3721 gttcatgcgg gcgttttcag aaatgtagcg ggcggtgatt tcgatagttt ccatgatact
     3781 tcctctttaa gccgataccg gcgatggtta agtggcagac acatcacctg ccacttttta
     3841 attatcgtac aatggggcgt taaagtcaac acaagtacgg attatattta catctattgc
     3901 ttacatcgcc tgcgtggcca tctcgttata caccgtctgc aatgtacttt ttaaaagccc
     3961 gcagcgtccc cacaatacgc gaccgggttt gttcgtcacc gtcgcgcagc tgctccagtt
     4021 tttcaataat tgctatttgc ggcagactcg tttcctcttt cagcttcacg atccccgcat
     4081 tgaacttcag caacgttgta tccgggactt catcgcccag ataaggccgc agccaggcac
     4141 attccgcgaa cgggtcaacc agccgctgta actctttagc cgtcgcttcc agcgcgcggc
     4201 ggtcagttcg gattgtgccg gtttgcggat ctacacagat gtcatgccag ttttcatgca
     4261 taaagctgtc tctgtagtga aaaccgttct cgccttgttc tgcgcaggcc aggaggctga
     4321 cgattgaatc tatcggccgc gtttgcagca tccgggccgt tgccataccc atcgcgttga
     4381 tcataatccc atgaaggccc agcgcttcct ggcggtattc ggcggcaata tcatcctgcg
     4441 ctatatccag ccagcgcatg gcgcctgacc aggcagacca gagcttttcg gccgcctcgc
     4501 gctgctgaag ggtaggctcg ctactggcgc gcaggctgag catcttttta gtcgcgtcat
     4561 taagcgcctt aaagctaata aggcgtgagc tttttgccgg aacggcgtta tgttcgaaat
     4621 cgaccgaccc cgccaggccg gtgacgtttt gcgccaggta catcgccagc tggttaaccg
     4681 ggtcgttgtt gttgtaagcc atgctgatcg ctgctgccgg tttgctggcg ttgttgttaa
     4741 tgtcggcaaa aaactgctgg cgcatttcaa gcggcaggcc aaccgtcaac aacaggctga
     4801 tggtgtcgcc ggtattcgcg tagtcccgga caaaatccat gatgcctagc gccctgtgct
     4861 gtccgtcgaa taacttcaga tctgcttcca ttgggatttt caggataccc acagacggcg
     4921 atagttcgct gggaaagaaa tctacgtcaa tatcaatatt tccggtgatc gagggcagaa
     4981 tatacggctt accgctgccg gtggcctcgg caacatagtt tctgatttta cgcgcgcgcg
     5041 ttctgtttgc ttcgcgctgg ctgcgggcca ttacatcgcc ctgatcatcc atcgccagaa
     5101 ggcgacgtaa aacggccatt ggcacagtca gcatgtactg ttcaacgcca ccctggacgc
     5161 cgcgtgttgc cggtaattcg aaaacatagt tatcagtatg cattttcagg ttccttcaca
     5221 ttcaggtcat gcccggactt atccgggcga aaaggttagc gatcgagaag cagttttttg
     5281 acgtcggcgc gccagttaag cgagtcgaaa taaacgagat attcgtcatg ggaaggaacc
     5341 gcattacgcg caaacataaa ctgatgtgcg gaaagccagc aatcgtcctg ctcggtgaat
     5401 acctgaatgt ccggcgtgcc atcggttgta gtgatctcgg cgtaccaggg gaaaacagca
     5461 cacatcatat cctcgtccgg ctcggcgcca ttcacttcat cctgaacgtg gaaccataca
     5521 taacccattg ccagggcagg ctcgttatct tgcgccggtt tcagtgaggt caattctggg
     5581 ttactgacat accagttgag gttaaaaaat tggtgggggg ttaatacacg cataaatctc
     5641 cttagctgcc gataccggca atttagcggg tggcggtgtt gcctcccgat gatttaatta
     5701 tcggtgatta cgcccttaaa gtcaatacaa gtacggaata tatttacctg tgtttatgcc
     5761 cgtcagggca tggaaggcga ccgcgccgga ctccaccgga
//
LOCUS       DAPOXO010000170         5661 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.170, whole genome shotgun sequence.
ACCESSION   DAPOXO010000170 DAPOXO010000000
VERSION     DAPOXO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5661
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.170"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            185..1981
                     /locus_tag="ROH59_004916"
     CDS             185..1981
                     /locus_tag="ROH59_004916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HDX4807290.1"
                     /translation="MFDKYRKTLVAGTVAITLGLSASGVMAAGFKPAPPAGQLGAIIV
                     DPYGNAPLTALVDLDSHVISDVKVTVHGKGEKGVDISYKVGNESLKTYDGVPIFGLYQ
                     KFANKVTVEWKENGKAMKDDYVVQTSAIVNNYMDNRSISDLQQTKVVKVAPGFEDRLY
                     LVNTHTFTAQGSDLHWHGEKDKNAGILDAGPATGALPFDIAPFTFIVDTEGEYRWWLD
                     QNTFYDGRDRNINKRGYLMGIRETPRGTFTAVQGQHWYEFDMMGQVLEDHKLPRGFAD
                     ATHESIETPNGTVLLRVGKSNYRRDDGVHVTTIRDHILEVDKSGRVVDVWDLTKILDP
                     KRDALLGALDAGAVCVNVDLAHAGQQAKLEPDTPFGDALGVGPGRNWAHVNSIAYDAK
                     DDSIILSSRHQGVVKIGRDKQVKWILAPSKGWEKPLASKLLKPVDANGKPITCNENGL
                     CENSDFDFTYTQHTAWISSKGTLTIFDNGDGRHLEQPALPTMKYSRFVEYKIDEKKGT
                     VQQVWEYGKERGYDFYSPITSIIEYQADRNTMFGFGGSIHLFDVGQPTIGKLNEIDYK
                     TKEVKVEIDVLSDKPNQTHYRALLVRPQQMFK"
     gene            1999..2667
                     /locus_tag="ROH59_004917"
     CDS             1999..2667
                     /locus_tag="ROH59_004917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HDX4807291.1"
                     /translation="MSKLGISSLFKTILLTAALAVSFTASAFTEGTDYMVLEKPIPNA
                     DKTLIKVFSYACPFCYKYDKAVTGPVSEKVKDIVAFTPFHLETKGEYGKQASEVFAVL
                     INKDKAAGISLFDANSQFKKAKFAYYAAYHDKKERWSDGKDPAAFIKTGLDAAGMSQA
                     DFEAALKEPAVQETLEKWKASYDVAKIQGVPAYVVNGKYLIYTKSIKSIDAMADLIRE
                     LASK"
     gene            2682..3353
                     /gene="dsbI"
                     /locus_tag="ROH59_004918"
     CDS             2682..3353
                     /gene="dsbI"
                     /locus_tag="ROH59_004918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide oxidoreductase DsbI"
                     /protein_id="HDX4807292.1"
                     /translation="MGIKGMWKDLRTSPVDTLVRWQEQRLLWLLMAVAMGTLIILAHS
                     FFQIYLYMAPCEQCVYIRYAMFVMVIGGLVAAINPKNIILKLIGCVMAFYGSILGLKF
                     SLKLNDIHHAVHNPDPDSLFGVQGCSTDPTFPFNLPLAQWAPNWFKPTGDCGYDAPIV
                     PDGVTLSSTQQWFVEMYQQSEGWYLLPPWHFMNMAQACMLAFGMCLVLLVIMSGAWAL
                     KIIRG"
     gene            complement(3399..4187)
                     /gene="ygiD"
                     /locus_tag="ROH59_004919"
     CDS             complement(3399..4187)
                     /gene="ygiD"
                     /locus_tag="ROH59_004919"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HDX4807293.1"
                     /translation="MSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVV
                     VSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPALAQHLVELLAPVPVT
                     LDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIML
                     VASGNVVHNLRTVKWHGDSSPYPWAMSFNEYVKANLTWQGPVEQHPLVNYLDHEGGAL
                     SNPTPEHYLPLLYVLGAWDGQEPITIPVDGIEMGSLSMLSVQIG"
     gene            4330..5103
                     /gene="zupT"
                     /locus_tag="ROH59_004920"
     CDS             4330..5103
                     /gene="zupT"
                     /locus_tag="ROH59_004920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDX4807294.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            complement(5165..5335)
                     /locus_tag="ROH59_004921"
     CDS             complement(5165..5335)
                     /locus_tag="ROH59_004921"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807295.1"
                     /translation="MFIAWYWIVLIVLLAGGYFLHLKRYCKAFRHDRDALLAARSKLD
                     KRSDKEVFEKHQ"
BASE COUNT         1518 a         1360 c         1315 g         1468 t
ORIGIN      
        1 ccctactatc cattaaacat aaatatttgt ttcaccgaat aacaacatat ttaaaagaaa
       61 cacaaaaaca ttctcactct ttattgaatt aatatttata ttcacgtaac gaatttatta
      121 gcaccctctc aacagtcgat attcatcatt attatatatt tgcgttatat aaggagatat
      181 atccatgttt gataaatata gaaaaacact cgtagccgga actgtggcga taaccctggg
      241 tttgtcagca tcgggggtga tggctgcggg ttttaaacca gcaccgcctg ccgggcagct
      301 tggggcgatt atcgtcgatc cctacggtaa tgcgccctta accgcgctgg ttgatttaga
      361 cagccatgtt atttctgacg tcaaagttac cgtccacggg aagggcgaaa aaggcgttga
      421 catcagctat aaagtgggca acgagtcact gaaaacttac gatggtgtac cgatttttgg
      481 tctttaccag aagtttgcga acaaagtgac cgttgagtgg aaagaaaacg gtaaggccat
      541 gaaagatgat tacgtggtgc agacttccgc catcgtcaac aattacatgg ataaccgctc
      601 catctccgac ctacagcaaa ccaaagtcgt taaagtcgcg ccaggttttg aagatcgcct
      661 ctatctggtt aatacccaca cctttaccgc ccaaggttcc gatctccact ggcatggtga
      721 gaaagataaa aatgccggta tccttgatgc gggtccggca actggcgcac tcccttttga
      781 tatcgcgcca ttcaccttta tcgtcgatac ggaaggcgaa taccgctggt ggttggatca
      841 aaacaccttc tacgatggtc gtgaccgcaa cattaacaaa cgtggttatc tgatgggtat
      901 ccgtgaaacg ccacgcggca cctttaccgc tgtacaaggt cagcactggt acgagttcga
      961 catgatgggg caggtgctcg aagatcacaa actaccgcgc ggatttgctg acgccactca
     1021 tgagtccatt gagacgccaa atggcacggt actgttgcgc gtaggtaaga gtaactatcg
     1081 tcgcgatgac ggcgtacacg tcaccaccat tcgtgaccat atcctcgaag tcgataaatc
     1141 tggtcgcgtt gtcgatgtat gggatctgac caagatcctc gatccgaaac gcgatgcact
     1201 gctcggcgcg ctggatgcag gtgcagtttg cgttaacgtt gaccttgccc atgcaggaca
     1261 acaggcaaaa ctggaaccag atacaccgtt cggcgacgcg ctgggtgtag ggccaggccg
     1321 caactgggcg cacgtgaact ctatcgccta tgacgcaaaa gatgactcta tcatcctctc
     1381 ctctcgccac cagggtgttg tgaagattgg tcgtgataag caagtgaaat ggatccttgc
     1441 gccctctaaa ggttgggaaa aaccgctggc cagcaagctg ctgaaaccgg ttgatgctaa
     1501 cggtaagcca attacctgta acgaaaatgg cctgtgcgaa aactcagact tcgactttac
     1561 ctacacccag cataccgcct ggatttccag caaaggaacg ctcaccattt ttgataatgg
     1621 cgatgggcgt catctggaac aacctgcctt accaaccatg aaatactccc gctttgtgga
     1681 atataagatt gatgagaaga aaggcaccgt tcagcaagtg tgggaatacg gtaaagaacg
     1741 tggctacgat ttctatagcc cgattacctc catcattgaa tatcaagccg accgtaacac
     1801 catgtttggc ttcggtggtt ctattcattt gttcgatgtc gggcagccaa ccatcggtaa
     1861 gttgaacgaa atcgattaca aaaccaaaga agtgaaagtg gaaatcgacg tgctgtcaga
     1921 taaacccaat cagactcact atcgtgcact gttagtccgt ccacaacaga tgttcaaata
     1981 attaagaagg gaataaaaat gtcgaaatta gggatctcat cactatttaa aaccatactg
     2041 cttaccgcag ctttggctgt ttcatttacc gcttctgcat ttaccgaagg cacggattac
     2101 atggttctgg aaaaacctat tccgaatgcc gacaaaacgc tgattaaggt atttagctac
     2161 gcctgcccgt tctgttacaa gtacgacaaa gcggttaccg gtccggtatc ggaaaaagtg
     2221 aaagatatcg ttgctttcac gccgttccat ctggaaacca aaggtgaata cggcaaacaa
     2281 gcaagcgaag tctttgcggt cttgatcaat aaagataaag cagcaggcat ttccttattt
     2341 gatgctaact ctcagtttaa gaaagccaag tttgcctact acgcggctta tcacgacaaa
     2401 aaagaacgct ggtctgacgg taaagatccc gctgccttta tcaaaactgg tctggatgcc
     2461 gcaggtatga gtcaggcgga ttttgaagcg gcactgaaag aaccagcagt tcaagaaaca
     2521 ctggaaaaat ggaaagcctc ttatgatgtc gccaaaatcc agggggttcc agcctatgtc
     2581 gttaatggta agtacttgat ctacaccaag agcatcaaat ccatcgacgc gatggcagac
     2641 cttatccgtg agttagcaag caaataacag ggaaacaggc tatgggtatt aagggaatgt
     2701 ggaaagatct tcgcacatca ccagttgaca cactggtcag atggcaggag caacgcttgt
     2761 tgtggttgtt aatggccgtt gcgatgggca cgttaattat cctggcgcac tctttcttcc
     2821 agatctatct ctacatggca ccctgtgagc aatgtgtata cattcgctac gccatgtttg
     2881 tgatggtgat tggaggattg gttgcagcga tcaatccaaa gaacatcatc ctcaagctaa
     2941 ttggctgcgt gatggcattt tacggcagca ttttgggact gaagttttcg ctcaaactga
     3001 acgatatcca ccatgcagta cataatccgg atcccgattc actgtttggc gtacagggtt
     3061 gctctaccga tcccactttt ccctttaacc tgccgctggc acagtgggca ccaaattggt
     3121 tcaagcctac cggggattgt ggctatgacg caccaatcgt tcctgatggc gtcacactga
     3181 gcagcacgca acagtggttt gtggaaatgt atcagcaatc tgaaggctgg tatctgctac
     3241 caccatggca ttttatgaat atggctcagg cttgtatgct ggcttttggt atgtgtctgg
     3301 tgctgctggt cattatgagt ggcgcatggg cgcttaaaat catcagaggc taactcagca
     3361 acacccgaag ccagtcattc tggcttcggg ttcttttatt aacctatctg caccgacagc
     3421 atacttaaac tgcccatttc tataccatcg accggaatgg taattggctc ctgcccatcc
     3481 cacgccccta agacatacaa caacggcaga tagtgctctg gcgttgggtt cgataacgcg
     3541 ccaccttcat ggtcgagata attcaccaga ggatgttgtt ccaccggccc ttgccacgtc
     3601 agattcgctt tcacatactc attaaacgac atcgcccacg gatacggtga actatcaccg
     3661 tgccacttca ctgtacgcag gttatgcacc acgttgccac tggcgaccaa cattatccct
     3721 tcatcacgca gcgccgcgag tttgcgcccc atttcgaaat gccaggcggc aggtttgcta
     3781 ctgtcgatac tcaactgcac catcgggata tcggcgtcag gatacatctt aatcagtacg
     3841 ccccacgagc cgtggtcgaa gccccaggct tctttatcca gcgtcacagg gaccggcgct
     3901 aacagctcaa ccagatgctg tgccagcgca ggtgaacccg gagcaggata atgcgtatcg
     3961 tacagcgcct gcgggaagcc accaaagtca tgaatcgtgg gcggcgtctc catcgcggtc
     4021 actcctgttc cacgggtaaa ccaatgagcc gaaaccacca caatcgcttg cgggcgtggc
     4081 aatgtcatcc ccaacttctg ccagctgcgg gtatacaaat tatcttccag cacgttcatc
     4141 ggactaccgt gacctaaaaa caatgctggc atacgtgttg aagacatgat gatatcctta
     4201 actaaaggtg tcattttgat atcctcacaa tacgcttgtt cggcggagta agaacccgga
     4261 taacaatgat gatgatcatc agttattttg acgatctgcc tgaaggtgaa gatttataag
     4321 gagttgtcga tgtcagtacc tctcattctg accatactgg cgggggcagc cacgtttatt
     4381 ggcgcgtttc tcggcgttct cgggcaaaaa ccctcgaacc gcttactggc gttttcgcta
     4441 ggatttgcgg cggggatcat gttgctcatc tcattaatgg aaatgcttcc tgccgcatta
     4501 gccgccgaag gaatgtcacc tgtgttgggt tatggaatgt ttatcttcgg tctgcttggc
     4561 tattttggtc tggaccgcat gttgccacat gcgcatccgc aggatttaat gcaaaaatcg
     4621 gtgcagccgt tgccaaaatc gatcaagcgc acagccattc tgctcactct cggtatcagt
     4681 ctgcataact tcccggaagg gattgccacc tttgtcacgg cgagcagcaa cctggagctg
     4741 ggatttggta tcgccctggc cgtagcgttg cacaatattc ctgaaggtct ggcggttgca
     4801 ggcccggttt acgcggcaac ggggtcaaaa cgtaccgcaa ttctgtgggc ggggatttcc
     4861 ggactggctg aaattctcgg tggtgtgctg gcatggttaa ttcttggcag catgatttct
     4921 ccggtggtca tggcggcaat catggcggcg gttgccggta ttatggtggc gctctcggtt
     4981 gatgaattaa tgccgctcgc caaagagatt gaccccaata ataaccccag ttatggcgtg
     5041 ctatgtggaa tgtcagtgat gggattcagt ttagtgctgc tacaaacggc aggaattggt
     5101 taaagatgat aatgacagat gttgcccatt gctaaaggca acatctgtat cgttattaaa
     5161 ggtattattg atgcttttca aacacttctt tatcggagcg tttatctaat ttacttcggg
     5221 cagctaacag cgcatctctg tcatggcgaa aagctttaca gtaacgttta agatgaagaa
     5281 aatagccacc agctagtaga acaattaata caatccagta ccaggcaata aacatccttt
     5341 tcaccttcaa aatttaacat tactaaacat ttagcgttaa aatttcacat atccaacgtt
     5401 gaatatattc atatactcgc atagttgtgg atcatgtata tgatttcgat catagtaagt
     5461 gttgtattat atctcatgat tgttcaaaaa acaatcgatc gataatattg attatgtatc
     5521 aattctccat aaaacattac tcaggataat aaaatttaat aagtatcact agatatatat
     5581 tatatctttg aagttattcc tccctccgat tttcataaaa aacactccct aatccacttc
     5641 aacacccgtg taaataactg t
//
LOCUS       DAPOXO010000171         5653 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.171, whole genome shotgun sequence.
ACCESSION   DAPOXO010000171 DAPOXO010000000
VERSION     DAPOXO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5653
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.171"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            442..1509
                     /locus_tag="ROH59_004922"
     CDS             442..1509
                     /locus_tag="ROH59_004922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX4807296.1"
                     /translation="MDKSKRHLAWWGVGALAVAAVVAWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRLEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHTRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPDDLVVRLPQ"
     gene            1506..4241
                     /gene="rbbA"
                     /locus_tag="ROH59_004923"
     CDS             1506..4241
                     /gene="rbbA"
                     /locus_tag="ROH59_004923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HDX4807297.1"
                     /translation="MMHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGGVMVLGGDMRDPKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDVLPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVVHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCALSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG"
     gene            4241..5365
                     /locus_tag="ROH59_004924"
     CDS             4241..5365
                     /locus_tag="ROH59_004924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4807298.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKVWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLIAIGGAFFTIALLRFRKTIGTMA"
     gene            complement(5474..>5653)
                     /locus_tag="ROH59_004925"
     CDS             complement(5474..>5653)
                     /locus_tag="ROH59_004925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312382.1"
                     /note="class II aldolase; catalyzes the reversible aldol
                     condensation of dihydroxyacetonephosphate and
                     glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis
                     and gluconeogenesis; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase"
                     /protein_id="HDX4807299.1"
                     /translation="KVNIASDLRKAFITAVGKAYVNNHNEANLARVMASAKNAVEEDV
                     YSKILMMNEGHRSVK"
BASE COUNT         1222 a         1464 c         1642 g         1325 t
ORIGIN      
        1 aaattatttt atattcggta tttattcgca catcagacga taataacgct atgtgatagt
       61 catcaggttt ccctgttacg gaaacctgtg caacagaatc tgtgaacctg tacagaatat
      121 ttttggaaaa aacaccagcg aacggaagaa catcgcgatg tatcacaagt tgatggcaat
      181 caaatagaca acatgaatat aactgttagt atttaattga tttcacttat gagtatgcgt
      241 gtttcattta cggccaggaa tgctgatgat gacaacatta ctacccgttt tcactaagcc
      301 ttccccattg gcgctcaatg ctctgtgcgc tggtcgtatt tgccatttcc ttcttatccc
      361 ggatggaaga atccgctgaa cgtcgttcgg tggcagttgt aacacgtgtc gattgcttac
      421 agggattatg gcgggtcgat tatggataag agtaagcgcc atctggcgtg gtggggtgtc
      481 ggggcactgg cggtggctgc cgtcgtggcg tggtggctgt tgcgcccggc gggtgtgccg
      541 gaaggctttg ctgtcagcaa tgggcgcatt gaagcgacgg aagtggatat cgccagcaaa
      601 attgccgggc gtatcgacac cattctggtg aaagaaggcc agtttgttcg agaaggtgaa
      661 gtgctggcga agatggatac tcgcgtgttg caggaacagc gactggaagc catcgcgcaa
      721 atcaaagaag cacaaagtgc cgttgccgcc gcgcaggctt tgctggagca acgccaaagc
      781 gaaactcgtg ccgcacagtc gctggttaat caacgccagg cagaactgga ctccgtagca
      841 aaacgtcata cgcgttcccg ctcactggca caacgggggg caatttctgc gcaacagttg
      901 gatgacgacc gcgccgccgc tgagagcgcc cgagctgcgc tggaatcggc aaaagctcag
      961 gtttctgctt ctaaagccgc tatagaggcg gcgcgcacca atatcattca ggcgcaaact
     1021 cgcgtcgaag cggcacaagc cactgaacgg cgcattgccg cagatatcga tgacagcgaa
     1081 ctgaaagccc cgcgtgacgg acgcgtgcag tatcgggttg ccgagccagg cgaagtgctg
     1141 gcagcaggcg gtcgggtgct gaatatggtc gatctcagcg acgtctatat gaccttcttt
     1201 ctgccaaccg aacaggcggg cacgctgaaa ctgggcggtg aagcacgttt gattcttgat
     1261 gctgcaccag atctgcgtat tcccgcgacc atcagttttg tcgccagcgt cgcccagttc
     1321 acgccaaaaa ctgtcgaaac cagcgatgag cggctgaaat tgatgttccg tgtcaaagcg
     1381 cgtatcccac cggaattact ccagcagcat ctggaatatg tcaaaaccgg attgccgggc
     1441 gtagcgtggg tgcgggtgaa tgaagaactt ccgtggcctg acgacctggt ggtgaggttg
     1501 ccgcaatgat gcatctggaa ctggttcccg tcccgcctgt cgcgcaactg gcgggcgtga
     1561 gccagcatta tggaaaaacc gttgcgctga acaatatcac actcgatatt ccggcccgtt
     1621 gcatggtcgg gctgattgga ccggatggtg tcggtaaatc gagcttgttg tcgttgattt
     1681 ccggtgctcg cgtcattgag cagggcggcg tgatggtgct gggcggcgat atgcgcgacc
     1741 cgaagcatcg ccgcgacgtc tgcccgcgca tcgcctggat gccgcagggg ctgggcaaaa
     1801 atctctacca caccttgtcg gtgtatgaaa acgtcgattt tttcgcccgc ctgttcggtc
     1861 acgacaaagc ggagcgggaa gtgcgaatta atgagctgct gaccagcacc ggattagcac
     1921 cgtttcgcga tcgtccggca gggaaactct ccggcgggat gaagcaaaaa cttgggctgt
     1981 gctgtgcgtt aatccacgac ccggaattgt tgattcttga tgagccaaca acgggggttg
     2041 acccgctctc tcgcgcccag ttctgggatc tgatcgacag tattcgccag cggcagagca
     2101 atatgagcgt gctggttgcc accgcctaca tggaagaggc cgaacgcttc gactggctgg
     2161 tagcgatgaa tgccggagaa gtgctggcaa ccggtagcgc cgaagagttg cggcagcaaa
     2221 cgcaaagcgc cacgctggaa gaagcattta taaatctgtt accgcaagca caacgccagg
     2281 cgcatcaggc ggtagtgatc ccaccgtatc aacctgaaaa cgcagagatt gccatcgaag
     2341 cgcgcgatct gaccatgcgt tttggttcct tcgttgccgt tgatcacgtc aatttccgca
     2401 ttccacgcgg ggagattttt ggttttcttg gttcgaatgg ctgcggtaaa tccaccacca
     2461 tgaaaatgct taccggattg ctgcccgcca gcgaaggtga ggcgtggctg ttcgggcagc
     2521 cggttgatcc aaaagatatc gatacccgcc gtcgtgtggg ctatatgtcg caggcgtttt
     2581 cgctctataa cgaactcacc gtgcggcaaa acctggagtt acatgctcgt ctgtttcata
     2641 tcccggaagc ggaaattccc gcgcgagtgg ctgaaatgag cgagcgtttt aagctcaacg
     2701 acgtcgaaga tgtattgccg gagtcattgc cgctcggcat tcgccagcgg ctatcgctgg
     2761 cggtggcggt gattcatcgc ccggagatgc taatcctcga tgagccgact tctggcgtcg
     2821 atccggtggc gagggatatg ttctggcagt tgatggtgga tctctcgcgc caggacaaag
     2881 tgactatctt catctccacc cactttatga acgaagcgga acgttgtgac cgtatctcac
     2941 tgatgcacgc cggaaaagtg ctcgccagcg gtacaccgca ggagttggtt gagaaacgcg
     3001 gagccgccag tctcgaagag gcatttatcg cttatttgca ggaagcggca gggcagagca
     3061 acgaagccga agcgccgcct gtggtacatg acactaccca cgcgccacgt cagggattca
     3121 gcctgcgccg tctgtttagc tacagccgcc gcgaagcgct ggaactgcga cgcgatccgg
     3181 tacgttcgac gctggcgctg atgggaacgg tgatcctgat gctgataatg ggttacggca
     3241 tcagtatgga tgtggaaaac ctgcgctttg cggtgcttga ccgcgatcaa accgtcagta
     3301 gccaggcgtg gacgctcaat ctctccggtt cccgttactt tatcgaacag ccaccgctca
     3361 ccagttatga cgagcttgat cgtcggatgc gtgcgggcga tatcacggtg gcaattgaga
     3421 tccctcccaa tttcgggcgc gatatcgcgc gtggtacgcc cgtggaactc ggtgtctgga
     3481 tcgacggtgc gatgccgagc cgcgccgaaa cggtaaaagg ctacgtgcag gccatgcacc
     3541 agagctggct acaggatgtg gcgagccgac agtccacacc cgccagccaa agcgggctga
     3601 tgaatattga gacgcgctat cgctataacc cggacgtaaa aagcctgccg gcgattgttc
     3661 cggcggtgat cccgcttctg ctgatgatga tcccgtcaat gctaagcgcc cttagcgtgg
     3721 tgcgggaaaa agagctaggg tcgattatca acctttacgt gacccccacc acccgtagcg
     3781 aatttttact tggcaaacag ctgccataca tcgcgctggg gatgctgaac tttttcctgc
     3841 tctgcgccct gtcggtgttt gtgtttggcg taccgcataa aggcagtttc ctgacgctca
     3901 ccctggcggc gctgctgtat atcatcatcg ccaccggaat ggggctgctg atctccacct
     3961 ttatgaaaag ccagattgcc gccattttcg gtacggcaat tatcacgttg atcccggcga
     4021 cacagttttc cgggatgatc gatccggtag cttcgctgga aggtccagga cgttggatcg
     4081 gcgaggttta cccgaccagt cattttctga ctatcgcccg cggaacgttc tcgaaagcgc
     4141 tggatctgac tgatttgtgg caacttttta tcccgttgct gatagccata ccgctggtga
     4201 tgggcttaag catcctgctg ctgaaaaaac aggagggatg atgcgccatt tacgtaatat
     4261 ttttaatctg ggtatcaaag agttgcgcag tctgctcggt gataaagcga tgctgacgct
     4321 gattgtcttc tcgtttacgg tgtcggtgta ttcgtcagcg accgttacgc caggatcgtt
     4381 gaacctcgcg ccgatcgcca ttgccgatat ggatcaatcg cagttatcga accggatcgt
     4441 taacagcttc tatcgcccgt ggtttttgcc accggagatg atcaccgccg atgagatgga
     4501 tgccgggctg gacgccggac gttatacctt cgcgataaat attccgccta attttcagcg
     4561 tgatgtcctc gccggacgcc agccggatat tcaggtgaac gttgatgcca cgcgcatgag
     4621 ccaggcattt accggcaatg ggtatatcca gaatattatc aacggtgaag tgaacagctt
     4681 tgtcgcgcgc taccgtgata acagcgaacc gttggtatcg ctggaaacac ggatgcgctt
     4741 taacccgaac cttgatcccg cgtggtttgg cggggtgatg gcgatcatca acaacattac
     4801 catgctggcg attgtattga ccggatcggc gctgatccgc gagcgtgaac acggcacggt
     4861 ggaacactta ctggtgatgc cgataacgcc gtttgagatc atgatggcaa aggtctggtc
     4921 gatggggctg gtggtgctgg tggtgtcggg attatcgctg gtgctgatgg tgaaaggcgt
     4981 gctgggcgta ccgatagaag gctcgatccc gctgtttatg ctgggcgtgg cgctcagtct
     5041 gtttgccacc acgtcaatcg gcatttttat ggggacgata gcgcgttcaa tgccgcaact
     5101 ggggctgctg gtgattctgg tgctgctgcc gctgcaaatg ctttccggtg gttccacgcc
     5161 gcgcgaaagt atgccgcaga tggtgcagga cattatgctg accatgccga cgacacactt
     5221 tgtcagcctc gcgcaggcca tcctctatcg tggtgccgga ttcgaaatcg tctggccgca
     5281 gttcctgacg ctgatagcga ttggcggcgc gttttttacc attgcgctgc tgcgattcag
     5341 gaagacgatt gggacaatgg cgtaaataca gtgcccgata cgcaagctta tcgggcctac
     5401 gcgatggtgc aatttattga attctagtgg ttttgtaggc cggataaggc gtcacgccgc
     5461 atccggcgag gatttatttt accgaccgat gcccctcatt catcatcagg attttgctat
     5521 acacatcttc ctcgacggcg ttttttgctg atgccatcac tcgtgccaga ttcgcctcgt
     5581 tgtgattatt cacatacgct ttgccgactg cggtgataaa cgctttgcgc agatcgctgg
     5641 cgatattcac ttt
//
LOCUS       DAPOXO010000172         5567 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.172, whole genome shotgun sequence.
ACCESSION   DAPOXO010000172 DAPOXO010000000
VERSION     DAPOXO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5567
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.172"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1764
                     /locus_tag="ROH59_004926"
     CDS             <1..1764
                     /locus_tag="ROH59_004926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein VasK"
                     /protein_id="HDX4807300.1"
                     /translation="LTFWMANLPEHPQWKTSPPPELTGAVRKILLRQIGVRNAENTLY
                     QNVLQQVSRNYADMTLADMTGDTLTESLFSTEQTVPGMFTRQAWEGQVREAIEQVVTA
                     RREEIDWVLSDRQQDTSADISPDTLRNRLTSRYFTDFAGSWLAFLNSIRWKKEDSLSG
                     ILDQLTLMADARQSPLIALTDTIAWQVATGRENRGLSDSLAKSAQELFNGKEKTPQQS
                     REGDVPAGPLDKTFAPLLRLLGDKSGGGGGDTQLNLQTYLTRVTRVRLKLQQVTNAPD
                     PQEMTQQLAQTVLQGKTVDLTDTRDYGRLIAASLGEEWSGFGQALFVRPVEQSWRQVL
                     TPAADSLNRQWQRAIVSHWNQDFAGRYPFKASQNDASLPLLAQYLRDDGRINQFIAAN
                     LSGVLKREGRYWVADAMNTQGLTVNPDFIRALNRLRDVADTAFASGDAGIHFELRAKP
                     ARDVMKTHLVIDGQELEYFNQKERWQRFNWPDEQWQPGASLSWTSTQAMERILADYRG
                     SWSLIRLLERAQVTPVDSSTFKVVWKAQDGLPLNYLLRVEQGKGPLALLELKNFRLPG
                     QVFLTGRSMKDAEEYGEDADE"
     gene            1757..3367
                     /gene="tssA"
                     /locus_tag="ROH59_004927"
     CDS             1757..3367
                     /gene="tssA"
                     /locus_tag="ROH59_004927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HDX4807301.1"
                     /translation="MSELLQKLTRSCFADRDALDVARTQAALWQTWLLPVTADTPVGE
                     DPGYHDDFLRIRDEMNKLSGADTGLICQLAESLLLTQAKDVRIATYYIWARLHRDGER
                     GLAEGLALLAGLVERFGTQLLPSRPASRKMALEWLAGEKMLDSLARYPEVAKEDFANI
                     VAALNQLSVSFTAWPEDQHSPSLMPLINALESRLAQSGGMNAVVPQNSSGVPAPSSPV
                     DAPQVQTITSGRDLLDQAKVLARYLNEQPQGWLSAHRLMKTLRWDTVHELPPDVDGKT
                     RLAPPRTESRNQLKRLYAQQNWTELLEQADLMFSTGVSHFWLDIQWYLHQALAKAGAP
                     WDRWTAVIRQDLALLLERLPGLENLAWNDGTPFADEVTRNWIAQQVMMREDGAWLAGK
                     AAVPTDDATNDVLALEPEALEMADSQGVEAALGWIQTRPGITTARQRLLLRLLMARVA
                     EQYGKNEMALLLLEELDTAAQGITLTQWEPELLFEVKARQLKLLRLRAHRYADKALLN
                     RKMEILLGTLVAIDPVRAAVLCDTQHKD"
     gene            3373..4791
                     /locus_tag="ROH59_004928"
     CDS             3373..4791
                     /locus_tag="ROH59_004928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HDX4807302.1"
                     /translation="MGTGYFLVRGDKTTCGGKIIEGADDHTIMGIPQARDMDRVTCGR
                     YPGMFIIVGGVPETDIHGRLMAGTLDSQSSCPCKARFIASMMDDTYETDDGESEAEQH
                     AQSAKKDLTSGSDSSSDDVKLDYRIKLSGNKILTPLNIPDYKEMINGGSTKNTEKIDF
                     TITNKGDEAEGLSLEVLDGNEVIYSERQTGKYFTKGEHAWQWDGYSNQGILDTTKLKS
                     KSLLVRLIALCGDMMIKVDYPLKTSANEEDWVDIEVNKNNKTVNIIWRLAVSDGGIKG
                     SNPKLSPVPYNDLVDLTKNGVEFYWSRNGSRGGGIGESIVTAIGVFKVNVKAEINITP
                     SMRTFSLISSLDPDFQASVSLSGFEKIYYNYGDSYKDIQDELQALLDANNRYKWDSAH
                     EMGHKVLDEYGEGSSPDYSWTHKGTSTLMQKTIPGNVMPAQGEIDVMKYGKYRPDMYT
                     RLVAADEDVQGLIWLSRIKFDD"
     gene            4784..5205
                     /locus_tag="ROH59_004929"
                     /pseudo
     CDS             4784..5205
                     /locus_tag="ROH59_004929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774033.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1459 a         1295 c         1571 g         1242 t
ORIGIN      
        1 ctgaccttct ggatggcgaa cctgccggaa cacccgcagt ggaaaacctc accgccaccg
       61 gaactgaccg gcgcggtgcg taaaatcctg ctgcgccaga ttggtgtgcg taatgccgaa
      121 aacaccctct accagaacgt gctgcaacag gtgtcccgca actacgccga tatgacgctg
      181 gcggacatga ccggggatac cctcactgaa tctcttttca gtacggaaca gacggtgccg
      241 gggatgttca cccgtcaggc atgggaagga caggtcaggg aagctatcga gcaggtggtg
      301 acggcgcggc gcgaggaaat cgactgggta ctcagcgacc gccagcagga tacctctgct
      361 gatatctcgc cggatacgct gcgtaaccgc ctcacctcac gctactttac cgactttgcc
      421 ggaagctggc tggcgtttct caacagcatt cgctggaaaa aggaagactc gctctccggc
      481 attctcgacc agctgacgct gatggccgat gcccgtcagt cgccactgat tgcactgaca
      541 gacactattg cgtggcaggt ggcaacaggc agggaaaatc gtggcctgtc agactcgctg
      601 gcgaaatcgg cacaggaact gtttaacggc aaggagaaaa cgccgcagca atcccgtgaa
      661 ggcgacgtgc ctgccgggcc gctggataaa accttcgcgc cgctgctgcg gttgctgggc
      721 gataagtcag gaggcggtgg tggtgatacg caactcaacc tgcaaacgta tctgacccgc
      781 gtcacccgcg tacgcctcaa actgcaacag gtgaccaacg cccccgaccc gcaggagatg
      841 acccagcaac tggcgcagac ggttttacag ggcaaaaccg ttgacctcac cgacacccgc
      901 gactacgggc ggttaatcgc cgccagtctg ggcgaagaat ggagtggctt cggtcaggcg
      961 ctgttcgtcc gcccggtgga acagtcgtgg cggcaggtgc tgacgcccgc agcggacagc
     1021 ctgaaccgcc agtggcaacg ggcgattgtc agtcactgga atcaggactt cgctggccgc
     1081 tatccgttca aagcctcaca gaacgatgcc tctcttccct tgctggcgca gtacctgcgc
     1141 gatgacggac gcatcaacca gtttatcgcc gccaaccttt ccggtgttct gaaacgtgaa
     1201 ggccgctact gggtggctga cgccatgaac acgcaggggc tgacggtcaa cccggacttt
     1261 atccgcgccc tgaaccgcct gcgcgatgtg gccgataccg cctttgccag cggcgatgcc
     1321 ggaatacatt tcgaactgcg ggcaaaaccg gcgcgtgacg tgatgaaaac gcatctggtg
     1381 attgacgggc aggaactgga gtatttcaac cagaaagaac gctggcagcg ttttaactgg
     1441 ccggatgaac agtggcaacc cggcgcatcg ctgagctgga ccagcacaca ggcgatggaa
     1501 cgcatactgg cggattaccg gggaagctgg agccttattc gcctgctgga acgggcgcag
     1561 gtaacaccgg tcgacagcag cacctttaaa gtggtgtgga aagcgcagga cggcctgcca
     1621 ctgaattacc tgctgcgggt tgaacagggt aaagggccgc tggcgctgct ggaactgaaa
     1681 aacttccgcc tgccgggaca ggtatttctg accggcagga gtatgaagga tgcggaagag
     1741 tatggggaag acgccgatga gtgaactgtt gcaaaagctg acccgtagct gttttgccga
     1801 ccgggatgca ctggatgtgg cgcgaacaca ggcggcgctg tggcagacat ggctgctgcc
     1861 ggtgacggca gacacgccgg tcggggaaga ccccggctac cacgacgatt tcctgcgtat
     1921 ccgcgacgaa atgaacaaac tgtccggtgc cgataccggc cttatctgcc agcttgccga
     1981 atccctgctg ctgacgcagg ccaaagacgt gcgcatcgcc acttactaca tctgggcgcg
     2041 actgcaccgc gacggtgagc gcggactggc tgaaggactg gcgctgttag ccgggctggt
     2101 ggaacgcttc ggtacgcaac tgctgccctc gcgaccggca agccgaaaaa tggcgctgga
     2161 gtggctggcg ggggaaaaga tgctcgacag ccttgcccgc tacccggagg tggcaaaaga
     2221 ggattttgcg aacattgttg ccgctcttaa tcaactgtcg gtttccttca ctgcatggcc
     2281 cgaagaccag cattccccct ccctgatgcc gctgattaac gcgctggaat cacgtctggc
     2341 gcagtcgggc gggatgaacg cggtggtgcc gcaaaacagc agcggcgttc cggcaccgtc
     2401 ttccccggtg gatgcgccgc aggtacagac catcacctcc gggcgcgacc tactcgacca
     2461 ggcgaaagtg ctggcccgtt atctgaacga acagccgcag ggctggcttt cagcacaccg
     2521 gctgatgaaa accctgcgct gggacacggt gcatgaactg ccgccggacg tggacggcaa
     2581 aacccggctg gccccgccgc gcaccgaatc acgcaaccag cttaagcggc tgtatgccca
     2641 gcagaactgg acggaactgc tggagcaggc cgacctgatg ttcagcaccg gtgtcagcca
     2701 tttctggctg gatatccagt ggtatctgca tcaggcgctg gcgaaggcgg gcgcaccgtg
     2761 ggacagatgg acagcggtta tccgtcagga cctggcgctg ctgctggagc gcctgccggg
     2821 gctggaaaat ctggcatgga acgacggcac gccgtttgcc gatgaggtga cgcgcaactg
     2881 gatagcgcag caggtcatga tgcgggaaga cggcgcatgg cttgcgggga aagccgctgt
     2941 gccgacagac gacgccacaa atgacgtact ggcgctggag ccggaagcac tggagatggc
     3001 tgacagtcag ggcgtggaag cggcgctggg ctggatacag acccgtccgg gcatcaccac
     3061 ggcacgacag cgcctgttat tgcgactgct gatggcacgg gtggcggaac agtacggtaa
     3121 aaacgagatg gcgctcctgc tgctggaaga actggatacc gccgcacagg gaataacgct
     3181 gacacagtgg gagccagagc tgctgtttga agtaaaagcc cgacaactga aactgctgcg
     3241 tctgcgggcg caccgctatg cggataaagc cctgctgaac cgaaaaatgg aaatcctgct
     3301 gggaacgctg gtggcaatcg atccggtacg ggcagcggta ttgtgtgata cgcaacataa
     3361 ggactgatgg caatgggaac aggctacttt ctggtcaggg gggataagac cacctgtggt
     3421 ggaaaaatta ttgaaggggc ggacgaccat acgatcatgg gtatcccgca ggcacgggat
     3481 atggaccggg tcacctgcgg cagatatccg ggaatgttta ttattgtggg cggcgttcct
     3541 gaaacagata ttcacggcag gctgatggcg gggacgctgg acagtcagag cagttgcccg
     3601 tgtaaagcac ggtttattgc gtcaatgatg gatgatacgt atgagacgga tgacggggaa
     3661 agtgaagcgg aacaacatgc gcagtcggcg aaaaaggatc tgacttctgg ttctgattca
     3721 tcctctgatg atgtaaaact ggattacaga attaaattat caggtaataa gatactgacg
     3781 ccactgaata tacctgatta taaagaaatg ataaacggtg gtagcacgaa gaatacagaa
     3841 aaaatagatt ttaccatcac aaataaaggc gatgaggctg aaggactttc cctggaagtg
     3901 cttgatggca atgaagtgat ttatagtgaa cggcagaccg gtaaatattt tactaaggga
     3961 gagcatgcct ggcaatggga tggctacagt aatcaaggca tactggatac aactaagcta
     4021 aaaagtaaat cactactcgt aagactgatt gctttatgtg gtgatatgat gataaaagtt
     4081 gattatccat tgaaaacttc tgcgaatgag gaagattggg tagatataga agttaacaaa
     4141 aacaataaga cagtaaatat aatatggcga ctggcagtta gtgatggagg gataaaagga
     4201 agtaatccta agttatcccc agttccttat aacgacttgg ttgacctgac caaaaatgga
     4261 gttgaatttt attggtctcg aaatggaagt cgcggcgggg ggattggtga aagtattgtt
     4321 acagcgattg gtgtttttaa agtaaatgta aaggctgaga taaatattac tccatccatg
     4381 cgaacttttt ctttgatatc atcattagat cctgactttc aggcatccgt tagtctatca
     4441 ggatttgaaa aaatatatta taactacggt gatagttata aggatattca agatgaatta
     4501 caggcacttc ttgacgctaa taacagatat aaatgggata gtgctcatga aatggggcat
     4561 aaagtactgg atgaatatgg agagggttct agccctgatt attcgtggac tcataaagga
     4621 acatctactc ttatgcaaaa aacaatacca gggaatgtta tgcccgctca gggagagatt
     4681 gatgtaatga aatatggaaa atatcgtcct gacatgtata ctcgattggt tgcagcagat
     4741 gaagatgttc aggggttgat ctggttaagc aggataaaat ttgatgacta gagtagttat
     4801 tgctttatta tttcttgccg gatgtacttc gcaaatgaag tattccaatg tcgtcaggat
     4861 taggaatgta tgttcctcag atattaatgt gtttattcct gagtatgttt ttggaggtaa
     4921 tgttattaag caacatcata tttacttacc tgttaatggg attgatgttt tgtcttattt
     4981 ttatactgaa aacatcaatg atggtttcca atatgaagaa gcattcaccg taaataaaga
     5041 tagctcgggt aattttgact atccgtttgt tatcttatca tcaggacgtg aaaaaaattt
     5101 gggaaaaacg atctaattga attatccagg gacatttcaa caaaagacga taagaagcat
     5161 ggggttgtaa agtacatgat agatagtcag aatatttgcc catagtatga ttcatatcat
     5221 aatcaactga aaaattgaca ttattaatca tttgtaattt tttgatacta ccaagtgaaa
     5281 tttgatgatt agattaatat tctctttttt attatgcaca ctgtgtgctg gatgtttatc
     5341 tcaaccattc tattcttgtt ccattgtcat ggtaaataca tgcaaagtat ctattagcat
     5401 ttcgacagtt aataattcaa cacattatga tggtaaagta agagataatt tccatcttga
     5461 tgtcggagaa cgaaagccaa ttgtatactt tatttacaca ggtagagagt cagatgtttt
     5521 taataaaaac cctgtgaata ttgtgtctga acttagtatt ttgatat
//
LOCUS       DAPOXO010000173         5256 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.173, whole genome shotgun sequence.
ACCESSION   DAPOXO010000173 DAPOXO010000000
VERSION     DAPOXO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5256
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.173"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            139..1347
                     /gene="trbA"
                     /locus_tag="ROH59_004930"
     CDS             139..1347
                     /gene="trbA"
                     /locus_tag="ROH59_004930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TrbA"
                     /protein_id="HDX4807303.1"
                     /translation="MSYNRQPVAEDPMQIWGAVGVLLILLLFVIWLFLPEVVYASCLI
                     LHTLWGLVDWGPFHNYAAPRYNLLAMTGNNAANISYSQWVNVMEQTIGILWMYLLPVT
                     LWCLWEWYQHPGQSRFTRRPVDITRLPHIFASLSPAIAPVLEDGDPEKLFHGGKRPER
                     RVALTPEAFVEQHTLITNMQLDVAAARRCFMAQLGKPLTSWKDMAPHEKALFAIFGLQ
                     YFLDDRKAALKLMDTLNLSCRIKSKRDSGKFCTPVYSLAKSAFKRVIKSDGAQQWLKQ
                     HRYVRSGLVWLYAHDLRLTPPNWIWLKGVDRTLFYALHRANTTKGFIEGAGVVAVARA
                     EAEAMRFGLPCPEPCVDEAVEGLRRDMLSLGLIWDEPQPDRDRKRRILTNWSLTDDIL
                     PRTPATDNEF"
     gene            1366..2436
                     /gene="trbB"
                     /locus_tag="ROH59_004931"
     CDS             1366..2436
                     /gene="trbB"
                     /locus_tag="ROH59_004931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TrbB"
                     /protein_id="HDX4807304.1"
                     /translation="MTIEYFATRIAKHISVQAIWPGGRTEIIAVLPQDALSGLVTRNN
                     QLIHIAFDAMGTRNRETVLIDKQEHNADQILTAIDSCLRLEYLMERRFSRTPLFRAII
                     ASVVLFVMAMIAVSLFRYVDRVFWDDTTPEAVQTAGEPRLLPPHLNHTVPLNEGIQLP
                     VPPKKDVQVPEKTLTSKNPEAAAARHNLAAVLKRNADRGMFTVNLSSGHERTLYAFLD
                     PACPNCRLLEPALKRLASDFNVVIYPVSVIGGEESTDRVAPLLCEKDAQKRAAGWHRL
                     YSADNGMMTPSEETTPADETCLKAARAAIDVNNVAFRKFGFAGTPWVLSDTGWHLPTG
                     ILQETGTLNLFLKTTDSESGHE"
     gene            2429..4720
                     /locus_tag="ROH59_004932"
     CDS             2429..4720
                     /locus_tag="ROH59_004932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbC"
                     /protein_id="HDX4807305.1"
                     /translation="MSEHRVNPELLHRTAWGNPVWNALQSLNIYGFCLVASLVASFIW
                     PLALPACLLFTLITMLVFSLQRWRCPLRMPMTLECADPSQDRMIKRSLFSFWPTLFQY
                     EVILESPASGIFYVGYQRVRDIGRELWLSMDDLTRHIMFFATTGGGKTETIFAWAINP
                     LCWARGFTLVDGKAQNDTARTIWYLARRFGREDDVEVINFMNGGKSRSEIILSGEKTR
                     PQSNTWNPFCYSTEAFTAETMQSMLPQNVQGGEWQSRAIAMNKALVFGTKFWCVREGK
                     TMSLQMLREHMTLEGMAKLYCRGLDDQWPEEAIAPLRNYLQDVPGFDLSLVRTPSAWT
                     EEPRKQHAYLSGQFSETFSTFTEAFGDIFAEDSGDIDIRDSIHSDRILMVMIPALDTS
                     AHTTSALGRMFITQKSMILARDLGYRLEGTDSDALEVKKYKGRFPYLCFLDEVGAYYT
                     DRIAVEATQVRSLDFALILMAQDQERIEGQTTATNTATLMQNTGTKFAGRIVSEGSTA
                     RTLKSAAGEEARARMNNLQRQDGIFGESWIDSPQISILMESKINVQELIELHPGEFFS
                     IFRGETVPSASFFIPDDEKSCSSDPVVINRYISVDAPRLDRLRRLVPRTTQRRIPSPE
                     NVSAIIGVLTAKPSRKRRKIRTEPHTIVDTFQQRIAGRQAAMAMLEEYDTDINARESA
                     LWETAVNTLKTTTREERRIRYITLNRPELPETKEENQISVRAERAGINLLTLPQDNNH
                     PTGRPVNGFHHKKNNRPDWDGMY"
     gene            complement(4758..>5256)
                     /locus_tag="ROH59_004933"
     CDS             complement(4758..>5256)
                     /locus_tag="ROH59_004933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="relaxase NikB"
                     /protein_id="HDX4807306.1"
                     /translation="SRTTTTDRCVVLCEPGGTPVYGNTGDLEARLQKNGSVRFRDRRT
                     GEFVCTDYGDRVVFRNHHDRNALADKLDLIAPVLFGRDPRMGFEPEGNDKQFNQVFAE
                     MVAWHNVTGRTGHEDYRITRPDVDHHREGSERYYRDYIAANSNDDASLPPPEQDKRWE
                     PPSPG"
BASE COUNT         1343 a         1362 c         1302 g         1249 t
ORIGIN      
        1 ccgcggctat tctaacgact ttcgtatctg caacaatcct tttatcgcac ggctaactcc
       61 tctggttagc tcttatcacc tgaaaataaa tttttaacct ttccgtttga tttaaattcc
      121 agaaatggag actttgccat gtcttacaat cgacagcctg tcgcagaaga tccgatgcag
      181 atatggggcg ctgttggtgt ccttcttatc ctgctgctat tcgtcatatg gttattcttg
      241 ccggaagtgg tttacgccag ctgcctgatt cttcatacct tatggggact ggttgactgg
      301 ggaccatttc ataactatgc agcaccacga tacaacctgc ttgccatgac cggtaacaac
      361 gccgccaaca taagctatag ccagtgggtt aacgtcatgg agcagaccat aggtattttg
      421 tggatgtacc tcttacctgt gacactctgg tgtttgtggg aatggtatca acatccggga
      481 caaagccgtt tcacccgcag accagtagat attacccgac tgccacacat ctttgcttcg
      541 ttgtcccctg ctatcgcccc tgtactggaa gatggtgatc cggaaaaact ctttcatggt
      601 ggcaaacgac ctgaacggcg ggttgctctc accccggaag catttgtcga acagcatact
      661 ctcatcacca atatgcagct cgatgttgca gctgcaagac gatgtttcat ggcccagttg
      721 ggtaaacctt taacgtcctg gaaagacatg gcaccacatg aaaaagcgct ctttgccata
      781 tttggccttc agtatttcct ggatgatcgt aaggcagcat taaagctcat ggatacactg
      841 aacctctcat gcagaattaa aagcaaacgg gacagtggga aattctgtac ccctgtttat
      901 tcactggcca aatctgcatt caaaagagtg attaaaagcg acggagcaca gcaatggctg
      961 aaacaacatc gctacgtccg cagtgggctg gtctggctgt atgcacatga cttgcggctt
     1021 acgccaccca actggatttg gctgaaaggc gtggacagaa cgctgtttta tgcattacac
     1081 cgcgccaata ccacgaaagg atttattgaa ggcgctggcg tggtggccgt tgcacgtgca
     1141 gaggccgaag ccatgcgttt tggccttccc tgccctgaac cctgtgttga tgaagcggtg
     1201 gaaggcttac ggcgggatat gctcagtctc ggtcttatct gggatgaacc acaaccagat
     1261 cgcgaccgga aacgccgcat tctgaccaac tggtccctca ccgacgacat cctgccccgc
     1321 acacctgcta cagacaacga attctgatta tccggagaac tgaaaatgac aatcgagtac
     1381 tttgcaacac gcattgcaaa acatatttcc gtgcaggcaa tctggccggg tggcaggaca
     1441 gaaattattg ccgtccttcc acaggatgcc ctgtcagggc tggtaacacg aaacaatcaa
     1501 ctgattcata tagcctttga cgccatgggc actcgtaaca gagaaaccgt cctgattgac
     1561 aagcaggagc ataacgctga ccagatactt acagctattg attcctgtct gcgccttgaa
     1621 tacctgatgg aacgccgctt cagcagaacg cctttgttcc gtgcaataat cgccagcgtt
     1681 gtactgttcg taatggcaat gattgccgtc tctctgttcc gctatgttga tcgtgtattc
     1741 tgggatgata caacgcctga agcagtacag acggcaggtg agccacgact gctcccccct
     1801 cacctgaatc acactgtgcc attaaatgaa ggcattcaac tcccggttcc cccgaaaaaa
     1861 gacgtccagg taccggagaa aacactcaca agcaaaaatc cggaagccgc agctgcccga
     1921 cataatctgg ctgctgttct gaagcggaac gccgatcggg gaatgtttac cgtcaacctg
     1981 tcatccggtc atgaacgaac cctttacgca tttctcgatc ctgcctgtcc taactgcaga
     2041 cttctggagc cagccttaaa acgcctggcc agcgacttca atgtcgttat ctacccggtt
     2101 tcagttattg gtggagagga atccaccgac cgtgtggcac cactgctgtg tgaaaaagat
     2161 gctcagaaac gtgctgccgg ctggcaccga ctgtattccg cagataacgg aatgatgacg
     2221 ccatcagaag aaacaacgcc tgcagatgaa acatgcctga aagcggccag agctgcgatt
     2281 gatgttaaca atgtcgcctt ccgtaagttc ggatttgccg gtaccccatg ggtgctgtcc
     2341 gacaccggct ggcatctgcc tactggaatt ctgcaggaaa ctggcacgct taatttattc
     2401 ctgaaaacca ccgacagcga gtctggccat gagtgaacat cgcgttaacc ccgagctttt
     2461 acaccgtaca gcctggggaa atcctgtctg gaatgcactc cagagtctca atatctatgg
     2521 cttttgcctg gtggcaagtc ttgtggccag ttttatctgg ccacttgcat taccggcatg
     2581 tctgttgttc acactgataa cgatgctggt atttagtctg cagcgatggc gctgccctct
     2641 tcgtatgccc atgacgctgg aatgtgctga cccgtcacag gacagaatga ttaaaagaag
     2701 ccttttcagc ttctggccaa ctctgtttca gtatgaggtc atcctggagt caccggccag
     2761 cggcatattt tatgttggtt atcaacgcgt cagggatata ggtcgggagt tgtggctgag
     2821 tatggacgat ctgacccgcc atataatgtt tttcgccacc accggtggcg gtaaaacgga
     2881 aaccatcttt gcctgggcga ttaacccgct ttgctgggca agaggattca cccttgtcga
     2941 tggcaaggca cagaatgata cggcaagaac gatctggtat ctggccagac gctttggccg
     3001 tgaagacgat gtggaagtca tcaacttcat gaacggagga aaatcccgca gtgaaatcat
     3061 tctgagtggt gaaaaaacgc gtcctcagtc aaatacctgg aatcccttct gttacagcac
     3121 cgaggcattc acagcggaga caatgcagtc aatgctgccc cagaacgtcc aggggggcga
     3181 gtggcagtcc cgggccattg ccatgaataa ggcactggta tttggtacta aattctggtg
     3241 tgtgcgcgaa ggcaaaacaa tgtcgctgca gatgctccgt gaacatatga ctctcgaagg
     3301 gatggccaaa ctttactgtc gtggcctcga tgatcagtgg ccggaagaag ctatcgcacc
     3361 gttacgtaac taccttcagg acgttcccgg tttcgacctg tcgctggtca ggacaccatc
     3421 agcctggacg gaagaaccca gaaaacaaca tgcttatctc tccgggcagt tttctgaaac
     3481 tttcagcaca ttcacggaag cattcgggga tatttttgct gaagattccg gtgatatcga
     3541 tatccgtgac agcattcaca gcgacaggat tctgatggta atgatccccg ctctggatac
     3601 atcagcgcat acaacgtctg ctcttgggcg aatgtttatc acccagaaaa gtatgattct
     3661 cgcccgtgat ttgggctacc gcctcgaagg aactgattcc gatgcactgg aagtcaaaaa
     3721 atataagggg cgtttccctt atctgtgttt ccttgatgaa gtgggggcat actatacgga
     3781 ccgtattgct gtggaagcca ctcaggtgcg ttcactggat tttgctctga ttttgatggc
     3841 acaggaccag gaacgtatag aaggacagac aacagccacg aatactgcaa cactgatgca
     3901 gaacacgggg acaaaatttg ccggcaggat tgtcagcgag ggtagtacgg ccagaacgct
     3961 gaaaagcgcc gccggtgaag aagccagggc gagaatgaac aacctgcagc gtcaggacgg
     4021 catatttggt gaatcatgga ttgacagccc acaaatcagc atcctgatgg aaagcaagat
     4081 aaatgttcag gagttgattg aacttcatcc tggcgagttc ttttctattt tccggggaga
     4141 aaccgtacca tcagcatcat tcttcatccc tgacgatgag aaaagctgca gcagcgatcc
     4201 cgttgttata aacaggtata tcagcgtgga tgcgccacgc ctggaccgtc tccgccgtct
     4261 tgttccccgt acgactcaac gtcgaatacc gtcaccggaa aatgtcagtg ccatcattgg
     4321 cgtcctgact gcaaaaccct ccagaaaaag acgaaaaatt cgcacagagc cgcacacgat
     4381 cgtggataca ttccagcaac gcattgcagg acgtcaggcg gctatggcaa tgctggaaga
     4441 gtacgacaca gatatcaacg cacgtgaaag tgccttgtgg gaaacagcgg tgaatacgct
     4501 taaaacgacc acacgggaag agcgacgaat tcgctatatc acgctgaaca gaccagaact
     4561 acctgaaaca aaagaggaaa atcagatttc agtgagagca gaaagagcag gtataaacct
     4621 gttaacgctt ccacaggaca ataaccaccc gacagggcgt cctgtaaacg ggtttcatca
     4681 taaaaaaaac aaccgtccgg actgggacgg aatgtactga acagtggccg cgccggattt
     4741 ctggcgcggc ctttttttta acctggagaa ggcggttccc agcgtttatc ctgctccggc
     4801 ggaggcagtg atgcgtcatc gttgctgttc gccgcgatat aatcgcggta gtagcgttca
     4861 cttccttcac ggtgatgatc cacgtccggt cgcgtaatcc tgtagtcttc gtgaccggta
     4921 cggcctgtca cattatgcca ggcaaccatt tcagcaaaga cctggttaaa ttgtttgtcg
     4981 tttccttctg gttcaaaacc catgcgtgga tcacgcccga ataataccgg tgcaatcaaa
     5041 tccagtttat ctgccagcgc attgcggtca tggtgattac ggaaaacaac cctgtcacca
     5101 taatccgtac agacaaactc tcccgtccga cggtcacgga aacgaacact cccgttcttc
     5161 tgcagacggg cctcgagatc accggtatta ccgtataccg gcgttccgcc cggttcacaa
     5221 agcacgacac agcggtctgt cgtcgttgtg cgtgac
//
LOCUS       DAPOXO010000174         5189 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.174, whole genome shotgun sequence.
ACCESSION   DAPOXO010000174 DAPOXO010000000
VERSION     DAPOXO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5189
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.174"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            149..2146
                     /gene="betT"
                     /locus_tag="ROH59_004934"
     CDS             149..2146
                     /gene="betT"
                     /locus_tag="ROH59_004934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004119118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDX4807307.1"
                     /translation="MSENDTIPKKSTSQINKAVFFTSALLIFLLVAFAAVFPDVADKN
                     FKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAML
                     FSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA
                     LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQ
                     VNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLAL
                     VLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLSWS
                     PFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNQGATGLANTV
                     QQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLASGGVANTPVW
                     QRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGLLKALRRDLTKR
                     ESLSMATIAPTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAMTLVQEELNKQG
                     TISHISDAVDDRIRLEVDLGNELNFIYEVRLRGYISPTFALAAMDNDEQQTEQHRYYR
                     AEVYLKEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR"
     gene            2209..3486
                     /locus_tag="ROH59_004935"
     CDS             2209..3486
                     /locus_tag="ROH59_004935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2254 domain-containing protein"
                     /protein_id="HDX4807308.1"
                     /translation="MISRWKWMLKQTIKKLWFRATLFAIVAIITALLSILFKSMIPES
                     VSVKVGAEAVDNILNILASSMLAVTTFSLSIMVTAYGSATTNVTPRATRLVVEDVTTQ
                     NVLATFIGSFLFSLVGIIALNMGAYGERGRVILFIVTLVVIALILITLLRWIQHLTSL
                     GRVGETTAQVEQAAIETFIARARNPCLGGYPWLENNEQPKGTVAVYPKKIGYVEYIDM
                     VKLSKLLTNDPRHVYLVAQPGSFIHPSMPVLYLSQGQESSINTDLLETIIVSDARSFA
                     QDPRFCLSVMAEIACRALSPAVNDPGTAIDVIGRGVRILSTYAQNKSDEIEVKYPSVH
                     VAPLQNNDLLEDFFSPVARDGASMREIQIRVLKGLSMLSKGWPEIFAEAAHTLAFETL
                     EHATHADHIDSDRYLIKSTYYNLFSGEYSNKKT"
     gene            3734..4390
                     /locus_tag="ROH59_004936"
     CDS             3734..4390
                     /locus_tag="ROH59_004936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX4807309.1"
                     /translation="MTGENRGRGRPRKTESTYADTRNDLIRSGLELLTQNGFLATGVD
                     AIVKNANVPKGSFYYYFKSKEDYAQTVLNAYDSFFEHKLKKHLHESSCTPMVRLENFI
                     NDACEGIKKYNFTRGCLVGNMMQESPGLPQSFIKVLQNILESWQALVAACLSDALSSG
                     EISSNMNNTQLAAIFWSGWEGAVMRSKLYCSTEPVYDFWSYFKTSVRYQSSQEATTGQ
                     "
     gene            complement(4571..4678)
                     /locus_tag="ROH59_004937"
     CDS             complement(4571..4678)
                     /locus_tag="ROH59_004937"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDX4807310.1"
                     /translation="MGNMAPFILRGVTLKGIDSVMFAKEKRAAIWQQAV"
BASE COUNT         1301 a         1196 c         1266 g         1426 t
ORIGIN      
        1 gaacaaatgg tagtgtccgc tattgccagt acacctcaac attccaccat gcattccgat
       61 taacgccgca tagccagttg aactttgcta ctttgtgaga ggtagtacct tctatccagt
      121 gcgaatttaa ttaatggaat aaatgattat gagtgaaaat gatacaatcc caaagaagtc
      181 tacaagtcag attaacaaag cggtattctt tacatctgct ttgctaattt tccttcttgt
      241 cgcctttgcc gccgtattcc cggatgtcgc cgacaaaaat tttaaactac ttcagcaaca
      301 aatcttcacg aatgccagct ggttctacat ccttgctgtg gccctgattt tactgagtgt
      361 cacgttcctt ggactctcac gctacggtga tatcaagctg ggcccggacc atgcgcagcc
      421 tgatttcagc taccactcct ggtttgcgat gcttttttcg gcagggatgg ggatcggcct
      481 gatgttcttt ggcgttgccg aacctgtaat gcattatctt tcgccacccg ttggcactcc
      541 agaaaccgtt gcggcagcta aggaagcaat gcgtctgacc tttttccact ggggactgca
      601 cgcatgggca atttatgcca ttgtggcgct gattctggcg ttcttcagtt accgtcacgg
      661 tctgccttta actctgcgct ccgcactcta tcccattatt ggcgatcgca tatacggacc
      721 tgtaggacat gcggttgata ttttcgctgt tataggcacg gtctttggcg ttgcgacatc
      781 actgggttac ggtgttttgc aggtgaatgc cggtttgaac catcttttcg gggtgcccat
      841 caatgaaacg gtgcaggtaa ttctgatcgt ggtcatcacg gggttagcga cgatttcagt
      901 ggtgtccggt ctggataagg gaatacgtat cctgtctgaa ctcaatctgg gtctggcttt
      961 gttgctcctg gcgctggtcc tgtgtctggg accaaccgtg cttctgctga agtcatttgt
     1021 ggaaaatacg ggcggttatc tttcggaact ggtgagtaaa acgttcaacc tttacgcgta
     1081 tgagcccaag tcgagcaact ggctgggggg ctggacatta ctgtactggg gatggtggct
     1141 ttcatggtcg ccgtttgtgg ggatgttcat cgcacgggtc tcccgcgggc gaaccattcg
     1201 cgagtttgtc accggcgtgc tgtttgttcc cgcgggtttt acgctaatgt ggatgacggt
     1261 gtttggtaac agcgcgatct atctcattat gaaccagggg gccacaggcc tcgccaatac
     1321 tgttcagcag gatgtggcgc tggccctgtt taatttcctg gagcatttcc cgttctcttc
     1381 tgtgctgtca ttcattgcaa tggcgatggt catcgtcttc tttgtaacgt ctgctgattc
     1441 gggggcaatg gttgtggata ctctggcatc aggtggagtg gcaaacacac ccgtctggca
     1501 gcgaatattc tgggcctcgc tcatgggcat tgttgcaatt gcgcttctcc ttgccggagg
     1561 gctaagtgcg ctgcaaacgg tgacaatagc gagtgcattg cccttctcag tgatcttact
     1621 aatatctata tacggacttt taaaagcttt gcgccgggat ttgaccaagc gtgaaagcct
     1681 gagcatggcg acaattgctc ctacggctgc acgtaaccca attccttggc agagaaggtt
     1741 acgcaatatc gcgtatctgc cgaagcgatc tcttgtgaaa cgttttatgg acgacgttat
     1801 ccagcccgcc atgacgctgg ttcaggagga actgaacaag caggggacga taagccacat
     1861 tagtgatgca gtcgacgatc gtattcgtct tgaagtcgat ttgggcaacg agctgaattt
     1921 tatatatgaa gtgaggcttc gcgggtatat ctcaccgacc ttcgcgctcg ccgcaatgga
     1981 taatgatgag cagcagactg aacaacatcg atattatcgc gctgaggttt atctcaaaga
     2041 aggcggtcaa aattatgatg tgatgggctg gaaccaggaa cagctgatta atgacatact
     2101 ggaccagtac gaaaaacacc tgcacttcct gcacctggtt cgttaatagc aacatgccgt
     2161 cctgggggcg gcaattatta tcccggccgc aatatgaggg aatgcagaat gatttcacgc
     2221 tggaaatgga tgctgaagca gacaattaaa aaactatggt tcagggcaac gttattcgca
     2281 attgtcgcga taataacggc ccttttatca attcttttta aatcaatgat acctgagtcg
     2341 gtttccgtga aggttggtgc ggaagcagtc gataacattc tgaacatact ggcatcgagt
     2401 atgctggcag tgaccacatt ttcgctgagt atcatggtca cagcctacgg ttcagccact
     2461 actaatgtga ctcccagagc tacgcgttta gttgttgaag acgtcaccac acaaaatgta
     2521 ctggccacct tcatcggttc ttttctcttc agtctggtag ggattattgc cctcaatatg
     2581 ggagcttatg gagaaagggg gagagtcatt ttattcattg tcacactggt tgtcattgcc
     2641 ttaatcctca tcacattgct tcgctggata cagcatttga cctctctggg gagggttggt
     2701 gagacaacgg cacaagtaga acaggcggcc atcgaaacat ttattgcgag agcaagaaat
     2761 ccctgtctcg gcggatatcc atggcttgag aacaatgaac agccgaaagg aacagttgca
     2821 gtttatccga agaagattgg ctatgttgaa tatattgata tggtgaaact tagcaagctg
     2881 ctgaccaatg atccccgtca tgtatacctc gtggcgcagc caggcagttt catacatccg
     2941 tccatgccag ttttgtacct gagtcagggc caggagtcgt caatcaacac cgatttactt
     3001 gagacgatta ttgtctcgga tgcacgttca tttgctcagg atcctcgatt ttgtcttagc
     3061 gtcatggccg aaatagcctg ccgggccctt tcccctgcag tgaacgatcc tggaaccgcc
     3121 attgatgtca ttggcagagg tgttcgtata ctttccactt acgcgcagaa taaatctgat
     3181 gaaatagaag tgaaatatcc ttcagtacat gttgcaccac ttcagaataa cgatctactg
     3241 gaagactttt tctcacctgt cgcgcgcgat ggtgccagta tgagggagat tcagataaga
     3301 gtccttaaag gactgtcgat gctgagtaaa ggttggcctg agatatttgc tgaagccgca
     3361 cataccctgg catttgaaac attagagcat gcaactcatg ctgaccatat agattctgat
     3421 agatatctaa taaaatcaac ttattataat ttatttagtg gcgaatattc taataaaaaa
     3481 acatagctgc agagcaagca attcggttgt tggcaagtca agggcaaagc attcgcgtga
     3541 gaatgggcgt atgctttgtg ccaaaagcaa acgttgctaa ttctgcactg ttcagcgatg
     3601 gcgcagtagc gacaggcact gccactgtcc agtcggcaaa agcgaacact ttgccactgc
     3661 ggggataaac tgattgaagc tctcgcgcaa aatcacttat tcttttgcgt taataaaatg
     3721 taggagatgg gtcatgacag gcgaaaatcg tggccgggga aggccgcgaa agacagaaag
     3781 tacctatgca gatactcgta atgatctgat ccgcagtggc cttgaactgc tgacgcagaa
     3841 tggttttctt gcgacgggag tcgatgccat tgttaaaaat gccaatgtcc ctaaaggctc
     3901 attttattac tactttaaga gtaaagagga ttatgctcag accgttctga acgcctatga
     3961 cagtttcttc gagcataaac tcaaaaaaca tctacatgaa tcatcctgca caccaatggt
     4021 acgtctggaa aatttcatca atgatgcctg tgaggggatt aaaaaataca attttacccg
     4081 cggctgcctg gttggaaata tgatgcagga gagtccgggg cttccccaat ccttcattaa
     4141 agtactacag aatattcttg agagctggca ggcacttgtt gcggcctgcc tgtccgacgc
     4201 gttatcttca ggcgaaataa gttcaaatat gaataataca caactggcgg ctattttctg
     4261 gagtggctgg gaaggtgcgg taatgcgttc caaactatat tgttctactg agccagtgta
     4321 cgacttctgg agctatttca aaacctcggt acgctatcag tcttctcagg aagcaacaac
     4381 tggccagtaa aaggggccgc agcccctaaa acttattata ctaagcctga gctcggcatc
     4441 catctaatta gctatattga atgactgcac gaccgcgaat tccgccactc agaagttttt
     4501 cagccacagt gatggcgtca ctgagcggat aaacggtagt gagactatcc attctggact
     4561 ctggcaaata ctataccgcc tgttgccaga ttgctgctct tttctctttc gcgaacatga
     4621 cgctatcaat ccctttcagc gtgacaccac gcagaataaa cggagccata ttgcccatca
     4681 aatccatccc ctgagccatg ccgcaggctg caacaatact gccatatcgg accccggcgc
     4741 aggcatttct ccagtaacag ggggttgtat tgtattgtat tttattgtgc cggttcaggt
     4801 gtgcgtttcc cggcgcgtct gcaccggctt aaccaaattc aacagggata aaatagtgca
     4861 aataaccgaa gtattacttg cagtaatcgg gggaagcatc cggggtttta ttcaacaggc
     4921 tgtagatcac tgactgcgtc tgttggccgt ccacttcacg cgtcattcga ccagagtaaa
     4981 tattgatgat tactagattc gtgtatttta tcaggcattt tacttgcgaa taaatcccct
     5041 tgctatccag cgaaaccaca caggtagcta ttaccatatg tggtaataca ctagttacag
     5101 gaaaaatatg caagttccgc aatacgttgt gtgttgctcc ttagccagga tcttttcttc
     5161 catgcgagat atgacaacaa ttttgagga
//
LOCUS       DAPOXO010000175         5064 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.175, whole genome shotgun sequence.
ACCESSION   DAPOXO010000175 DAPOXO010000000
VERSION     DAPOXO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5064
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.175"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..915
                     /locus_tag="ROH59_004938"
     CDS             <1..915
                     /locus_tag="ROH59_004938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2345 domain-containing protein"
                     /protein_id="HDX4807311.1"
                     /translation="DHVTIQNYKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQL
                     NLGHLVDAGKQQRGEGFELRTDLWGAVRAKKGIFISADAQDKAQGQVREMADIISELN
                     SLSDKIQKLSDDAATANADPADMAAQVALITSRINDLTASVILMHAPKGVAVASGEHL
                     QLAAVKNLQINAGNNADIGVVKNMFIGVGRALSVFVRKAGIKLIANKGAVSVQAQHDL
                     MELLAKKSIEIVSTEDEIRISAKKKITINGGGSYIRIEGSGIEPGTPGDYNVKAVHYG
                     RMGKAHEPVELQMLAEKVDEPPVKFFFS"
     gene            927..3290
                     /locus_tag="ROH59_004939"
     CDS             927..3290
                     /locus_tag="ROH59_004939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family peptidase"
                     /protein_id="HDX4807312.1"
                     /translation="MIISPPFIRAKNNNENDAHWIERMMPVEPDRDYPINYGGSWHGG
                     IHVRHTNSDRQPEYVRAIADGVVVSIRNPSDQAACSLPPLNYNGSTDDGYVLLRHETE
                     IGTGEDGNIVYYSLYMHLEKIEEGISEGNKVYRKSSLGMPGHVDGDRGLHFQIFCDDD
                     NLRKITGRTTPEMDVSRHGRTDVVYGDIYFYLPPGTRFYRSAPENNAVDNTGEVFQST
                     EPLVVTMCFDTGHCIMTTRRANPVIPSRYDIVGEVLTDADGTDYEYNLYSAALRLYPQ
                     SPSAGFELLRFGRVINTEHETLIPANAPLWRTVSYPGGQGVINLAADVVTKFSDGDFP
                     HWSGWRLVDDDADSNSQCNSVILRGGGFTDFRQMICHFPLEWCNTGIEARYGWLKEGV
                     IQERQENEANSDLSLGTDYYRPNNVEYNTTGDSHGESPQSAISEMPDLSYEQSNAYEN
                     AVRVLLLGEEDWQTLVKHIKALCFDTSSIAEGRVWHFNPGEFIKHFRKCGWVDKAILK
                     RIFASGTNDRDRAVIEQKVDIYGTAINIVMNKYIMNSPLRRAHFLGQGAVESSRLRSM
                     QEKSQYQTVDENGRPVGGGIVPDSLRDENSDLGHWYGAIETEVDGYFSGVKYNSGGGR
                     IAGSYDWILGNCDTEDAQKFRGRGFKQLTGRSNYAEYWVYRAWIDTNSFTAKWWEDPL
                     WRLHDRRRLTRIPANIEEPHRVTRSEYNCIDTGGFFIVKTVDRRGTRSSITRAMDQDS
                     EVIHLNNTTIDTTDEQTIRSVSRAINGGENGLPDRITFTRAAKKVLI"
     gene            3287..4144
                     /locus_tag="ROH59_004940"
     CDS             3287..4144
                     /locus_tag="ROH59_004940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807313.1"
                     /translation="MKKSFFLFLYFISLSAYPGDENAYIYGNDGTIEGIKYNYLDNVI
                     KFNIGDMSFDVFSKDNFFLKKCLLDNYSDSIDTGISFLTTDHEAIVFQSSGRFVLTKD
                     VIDICNSSEEKHAEVYPPVNIGMIADMNFRKNVALIYHPMGNISGKMVYQAELSKFVK
                     KNYRSSSFLTEVDPEKIQYLITGRFFYNGSYRDLEKKSYSGPFDLVSGVISPDAKYVD
                     PFGLGCDIDKVNHSIPHVYEISTAQRVAFKSDPALSAIINKEQIDKKCRQLLKASASL
                     KDLGGYLSQ"
     gene            4608..>5064
                     /locus_tag="ROH59_004941"
     CDS             4608..>5064
                     /locus_tag="ROH59_004941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX4807314.1"
                     /translation="MDVPVLNFDHSHHKLKIRGLQSPVDVLTFEGREQLSTPFRYDIQ
                     FTSTDKAIAPESVLMQDGAFSLTAPPVQGMPVQTALRTLHGVITSFKHLSSSQDEARY
                     EVRLEPRMALLTRSRQNAIYQNLTVPQIVEKILRERHQMRGQDFVFNLKS"
BASE COUNT         1491 a          981 c         1281 g         1311 t
ORIGIN      
        1 gaccatgtga ccattcagaa ctacaagcgt aacgtgctgc gcaccccggc gaacaacaaa
       61 atccgcctcg acgatgagcg cggcaaagag catatcaagg tcagtaccga gtacggcggc
      121 aagagccagc taaacctcgg ccatctggtg gatgccggaa aacagcagcg cggggaaggt
      181 tttgaactgc gtaccgatct gtggggtgca gtacgggcaa agaaaggcat ctttatcagc
      241 gccgacgcgc aggataaggc gcagggtcag gtacgcgaaa tggccgacat tatcagcgaa
      301 ctgaacagcc tgagcgataa aatccagaaa ctgtctgacg atgcggccac ggcgaacgcc
      361 gatccggcgg atatggccgc gcaggtggcg ctgataacca gccggataaa tgacctgacc
      421 gcctcggtga ttttgatgca cgcgccgaaa ggtgtggcgg tcgccagcgg cgagcacctg
      481 caactggccg cagtgaaaaa cctccagata aatgcgggaa acaacgccga tatcggcgtg
      541 gtgaagaata tgtttatcgg cgtagggcgg gcgctgagcg tgtttgtgcg caaggcgggt
      601 atcaaactga ttgccaataa aggcgcagta tcggtacagg cgcagcacga tctgatggag
      661 ttactggcga agaagtcgat agagatcgtc agtactgagg acgagatcag gatttcagcg
      721 aagaaaaaaa taacgattaa tggtggtgga agttatatcc ggattgaggg tagcggcatt
      781 gagccgggaa cgccggggga ttataacgtc aaagcggtgc attacgggcg tatgggaaaa
      841 gcacatgagc ctgttgagtt acaaatgttg gcagagaaag tagatgagcc acccgtaaaa
      901 tttttctttt cttaaggata taagaaatga ttattagccc gccatttata cgagcgaaaa
      961 ataacaatga aaacgatgct cattggattg aaaggatgat gccagttgaa cctgaccgtg
     1021 actatcccat caactatggg ggatcatggc atggaggcat ccacgttaga catacaaaca
     1081 gtgacaggca accagaatat gtccgtgcca ttgctgatgg tgtcgtggta tctattcgca
     1141 atccctctga ccaggcagca tgtagtcttc cgccgctcaa ttataatgga agcacagacg
     1201 atgggtatgt tctgcttcgt catgaaactg aaataggcac tggtgaggac ggcaatattg
     1261 tttattactc tctttacatg cacctggaaa agattgaaga gggtatcagt gaaggaaata
     1321 aagtctaccg gaaatcgtca ctgggaatgc cggggcatgt cgacggggat cgcggcctgc
     1381 acttccaaat tttctgcgat gatgacaatc tgagaaaaat aaccgggcgc actacacctg
     1441 agatggatgt gagccgtcat gggcgtaccg acgtggttta cggggatatc tatttttacc
     1501 tgccgcccgg tacccgcttt tacaggagtg cgccggaaaa caacgcagta gataacacag
     1561 gtgaagtttt tcagagcacg gaaccgttgg ttgtcaccat gtgttttgat actggccatt
     1621 gtatcatgac tacccgcaga gcaaatccgg tgataccaag ccgttatgac attgtgggag
     1681 aagtgttgac ggatgctgac ggcactgatt atgaatacaa cttgtacagt gctgcactga
     1741 gactttatcc gcaaagtcca agcgcagggt ttgagttact gcgctttggt cgggttatca
     1801 ataccgagca tgaaacactg atacccgcga atgcgccact gtggcgaacc gtgagctatc
     1861 ccggtgggca aggagtgata aatctggcgg cagatgttgt gacaaaattt agcgacggtg
     1921 attttccgca ctggagtggc tggcgactgg tagatgacga cgctgacagc aacagtcagt
     1981 gcaattcagt aatattacgt ggtggtggtt ttacggattt tcgtcagatg atttgccact
     2041 tcccactgga gtggtgtaat acgggaatag aagcgcgtta cggctggttg aaagaagggg
     2101 taatacagga acgtcaggaa aatgaggcta acagcgattt atcattaggt acggattact
     2161 acaggccaaa taatgtcgaa tataatacga ctggagatag ccatggagaa tctcctcagt
     2221 cagctatatc agaaatgcca gatttgtctt atgaacagtc aaatgcttat gaaaatgccg
     2281 tcagagtttt attactggga gaagaagact ggcagacgtt ggtgaagcat attaaggcac
     2341 tgtgttttga taccagtagt attgctgaag gacgggtttg gcattttaat ccgggtgagt
     2401 ttattaagca ttttaggaag tgtgggtggg ttgacaaagc aatattgaag cgaatttttg
     2461 cctctggtac taatgaccgt gatagagcgg ttattgaaca aaaagttgat atatatggta
     2521 cggctataaa tattgttatg aataaatata taatgaattc tcctctgaga cgtgctcact
     2581 ttctggggca aggggcagtg gaatcttccc gtttaagaag tatgcaggaa aaaagccagt
     2641 atcaaactgt tgatgaaaat ggtcggccag tcggcggagg tattgttccg gactcattac
     2701 gtgatgagaa ttcggacttg ggtcattggt atggtgcaat tgagactgag gtcgatggat
     2761 acttctctgg tgttaaatat aattctggtg gaggacgaat tgcaggctca tatgactgga
     2821 tactaggaaa ctgcgacact gaggatgccc agaagtttcg tgggcgaggt tttaagcagt
     2881 taactggtcg atcaaattat gccgaatatt gggtctatcg tgcctggata gatacgaata
     2941 gttttaccgc taagtggtgg gaagaccctc tgtggcgctt acatgatcgt cgtcgtttaa
     3001 ctcgcatacc ggctaatatc gaagagcctc acagggttac cagaagcgaa tataactgta
     3061 tcgatactgg tggattcttt attgttaaga ccgttgatcg tcggggtact cggtcaagta
     3121 ttaccagagc gatggatcaa gacagtgaag ttattcattt gaacaatacc acgatagata
     3181 caacggatga acaaacaata agaagtgtgt cccgtgcaat taatggtggt gaaaatggtt
     3241 tgccagacag gataaccttc acacgcgcag ctaagaaggt tttaatatga aaaagagttt
     3301 ctttttattt ttatatttca tatccctgag tgcatatcct ggagatgaaa atgcatacat
     3361 atatggtaac gatggaacaa ttgaaggaat taaatacaat tatctcgata atgtaataaa
     3421 gttcaatatt ggtgatatgt cttttgatgt tttcagcaaa gataattttt tcttaaagaa
     3481 atgtcttctg gataactaca gtgacagtat agatacaggc atttcatttt taacaacaga
     3541 tcatgaagca attgtttttc agtcatcggg tcggtttgtt ttaacaaaag atgtaatcga
     3601 tatatgtaat tcttctgaag aaaagcatgc ggaagtttat ccacctgtca atattgggat
     3661 gattgctgac atgaacttca ggaaaaatgt tgctcttata tatcacccaa tgggtaatat
     3721 ttcaggaaaa atggtatatc aggctgagtt gtcaaagttt gttaaaaaaa attatagatc
     3781 aagcagcttc ttaacggagg ttgatcctga aaaaatacag tacctgataa cgggtaggtt
     3841 tttttacaat ggtagttaca gagatttaga aaaaaaaagt tattcaggcc catttgatct
     3901 cgtctcaggc gttatctctc ctgatgcaaa atatgtagat cctttcggtc tggggtgtga
     3961 tattgataag gtcaatcata gtataccaca cgtgtatgaa atatccacag cacaacgagt
     4021 tgcatttaaa agcgatccag cgttatctgc gataataaat aaagaacaaa tagataaaaa
     4081 gtgtcggcag ttattaaaag catctgcatc tttgaaagat ttaggtggat atttaagtca
     4141 gtagaatatg tcaccgttac tctactgtgc tataggagat agcgaagaag agttttttca
     4201 atcaaatatt gccagagttt tattattggt tgaagaagac ttgaagacgt tggtgaacaa
     4261 tttcaagagg ctatttttta atgccaatgg tattgctgca ggataagttt ggcattttat
     4321 ctcaggtaac tttataaatt atttccataa atgcggaaaa atcacaaaaa gcttttttat
     4381 ttcttcattc ttttatgata ggtcgtcagg aacaacactg accagcatat ttaggaggag
     4441 agcgtatata tttttcacga agtttcatca aactatacga cagtacagaa gaattgtcat
     4501 attttaaatt ataactctaa tgtaataatt cattatccca gaatgtatcc gaacaagaaa
     4561 taacggctcg ttattctttg ttagataaat gaaggagtac aaagaaaatg gatgttcctg
     4621 ttctgaattt cgaccactca caccacaagc tcaaaattcg cggcctgcaa agtccggtgg
     4681 atgtgctgac cttcgaaggc cgcgaacaac tgagtacccc gttccgctac gacattcagt
     4741 ttaccagtac cgataaagcc atcgcgccgg agtcggtgct gatgcaggac ggcgcattca
     4801 gcctgacggc accaccggta cagggaatgc cggtgcagac tgccctgcgc accctgcacg
     4861 gcgtcattac cagctttaaa cacctctcct cgtcacagga cgaagcccgt tacgaagtgc
     4921 gccttgaacc ccgtatggcg ctgcttaccc gcagccgcca gaacgccatc taccagaatc
     4981 tgacggtgcc gcaaatcgtc gaaaaaatcc tgcgcgagcg gcaccagatg cgcggtcagg
     5041 acttcgtgtt taacctcaaa agcg
//
LOCUS       DAPOXO010000176         4990 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.176, whole genome shotgun sequence.
ACCESSION   DAPOXO010000176 DAPOXO010000000
VERSION     DAPOXO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4990
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.176"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..794)
                     /locus_tag="ROH59_004942"
     CDS             complement(<1..794)
                     /locus_tag="ROH59_004942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1705 domain-containing protein"
                     /protein_id="HDX4807315.1"
                     /translation="MSCIKEKSKYAFERAKQFYFMLWCKESLIYLLFSVLVTWCCGYT
                     VKNPLGNVLILFLMLLLGRQNVISATCVCIFLLLSAFYAPVGMIYGKINNSFIASVMQ
                     TNLNEAGEFITGIPVLYFIVSLIIAAFTFWFWRKRDKSQRGFIFLLFFIVLSVNAWPK
                     RMVTNVMTGIAETRDEMMRYESLKHNQKDSWDIVNVEKKYKTIIIVIGESVRRDYLSV
                     YGYPLPTTPWLNSAPGIFINGYFSAAPNTIGSLSRTLTLDYTETGNP"
     gene            complement(994..1449)
                     /locus_tag="ROH59_004943"
     CDS             complement(994..1449)
                     /locus_tag="ROH59_004943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 family protein"
                     /protein_id="HDX4807316.1"
                     /translation="MRDKSEVLTGAQKNRFGLILYIILLSVIYILITRLNLTTTYYSL
                     YSSLDENSQVTEYFIISIATFLFLAALCLFFIYSFFKRKRVVGKLLLCIYILYISHYA
                     ITFVYCLYVVGAECMTTGKIEHILIDIIIAMLSLLYVCLSGRARHIFVN"
     gene            complement(1538..2161)
                     /locus_tag="ROH59_004944"
     CDS             complement(1538..2161)
                     /locus_tag="ROH59_004944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001466373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDX4807317.1"
                     /translation="MQEHIDYQIEKYQFRARNESPRLMRQWADVMYECRETGAGARER
                     LRTALLNVDYVTSFELPFRLLLTRTPQMIDTLRREWLLSQKKALFNGRQRGCVYSLQN
                     DLSGVPDCFSYSLATRIRRMDCYGMTTRCFTDIAGQVKAPTARLKLALESGLLVTALD
                     GLFWLGTQRIAADVQRLRQSGMVIVTREVEVSDSLTGTTRLVSAYTL"
     gene            2326..2793
                     /locus_tag="ROH59_004945"
     CDS             2326..2793
                     /locus_tag="ROH59_004945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDX4807318.1"
                     /translation="MIKYIFSLAIIFSGSLCAAQIQGNVIRVLDGDTLEILQDKKTVR
                     VRLANIDAPEKKQPFGRWSASQLKDLVAGKPVTVQYLQTDRYNRILGRVYTADGTEAN
                     REQIRKGAAWVYPDYNKDYTLPALQRDARALKRGLWADENPVPPWAWRKQNKK"
     gene            2944..3120
                     /locus_tag="ROH59_004946"
     CDS             2944..3120
                     /locus_tag="ROH59_004946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807319.1"
                     /translation="MNLVDAFVTKVISGPYEEYGKWWVDVEYISWGVPGKSRLMFDSR
                     EQAQEVQEGFRFLT"
     gene            3813..>4990
                     /locus_tag="ROH59_004947"
     CDS             3813..>4990
                     /locus_tag="ROH59_004947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HDX4807320.1"
                     /translation="MNIWYIVGTICLLFALLIWLFLPDIVFATCLILHTMWGMTDWGP
                     FHHFAAPRYNLLANTANNAATITFSQWLDVMSQTVGILWLILLPMTIGFLWMWFQHPA
                     QPRFTRRPLNIHTLPHLFSSLSPAIAPVLADGDSNRLFHGQKRPERRVALTPEVFVAQ
                     NNLIRNMRLDVAATRQCFMAQLGQPLTTWKDMAPHEKALFAVFGLQFFLGDRKSAVSL
                     MNNLNLSCRLKSKRDQGRFSTPVYSLARNAFIRVIKTEDAQQWLRQHRYVRSGLVWLY
                     AHDLRLTPPNWLWLKGVDRTLFYALHRANTTKGFIEGAGVVAVARAENEASRLGLPCP
                     EPCVEEAIEGLRRDMLGLGLIWDEPQPDRDRKRQIRTRWSLTDDVIPRRHDNDEDTDT
                     G"
BASE COUNT         1425 a         1272 c         1032 g         1261 t
ORIGIN      
        1 ggattccctg tttcagtgta atcaagcgtc agtgttctgc tgagtgaacc tatcgtattc
       61 ggcgctgctg agaaataccc attaataaat atacccggag cagaattcag ccatggtgtt
      121 gtcggcaaag gatacccata aacagaaaga taatcccgtc tgacactttc accaattacg
      181 ataattatgg ttttatattt cttctccaca ttcacaatat cccatgagtc tttctgattg
      241 tgtttcagcg attcatatcg catcatttca tctctggttt cagctatccc tgtcattaca
      301 ttcgtaacca tacgttttgg ccatgcattt actgacaata cgataaagaa caacagaaag
      361 ataaatcccc gctggctttt atcacgctta cgccagaacc agaatgtaaa agcagcaatg
      421 atcagtgaaa caataaaata aagaacaggt atgcctgtga taaattcacc tgcctcattt
      481 agatttgtct gcattacaga cgcaataaaa ctgttgttta tttttccgta aatcatccca
      541 accggagcat agaatgcact taacaaaaga aagatacaga cacacgttgc tgaaataaca
      601 ttctgccgcc ccaacaacaa catcaggaac aatataagca cattccccag ggggtttttc
      661 actgtatatc cgcaacacca tgtaacaagc acagaaaaca acagataaat cagtgactct
      721 ttacaccaca acataaaata aaactgtttt gctctctcaa aagcatattt tgatttttct
      781 ttaatacaag acacgccagt cattttcctg tacaaacaca gacgatcatt tcaacgcatg
      841 gatatttata tgaaacagtt cacaaaaata ccctaccctg tccagcaaga tttacatatt
      901 atcaggttct gtgtttacag caactgctcc ccgaaccaga ttattcgcat aacccgatga
      961 aggcctcata accataaaac actcagaata catttagtta acaaaaatat gtcttgccct
     1021 cccggaaagg caaacataca aaagagaaag catggctata ataatatcaa tcaaaatatg
     1081 ctcaatcttt ccggttgtca tacactcagc accgacaaca taaagacaat aaacaaaagt
     1141 gatagcatag tgtgatatat aaagaatata aatgcacaga agtaatttcc cgacaactct
     1201 tttccgttta aagaaagaat aaatgaagaa caaacataaa gccgccagaa aaagaaatgt
     1261 agctatagat attataaaat actccgtcac ctgtgaattc tcatccagag atgaatacag
     1321 cgaataatat gtggttgtga gattaagcct tgttatcaat atataaataa ctgataatag
     1381 tataatataa agaatcagac caaatctgtt tttctgcgct ccggttaata cttctgattt
     1441 atctcgcata aaaatatcct gtctgtaatc tgtcccggta aacaatggta aatttcagaa
     1501 tcagtgcgaa tacggtaaca aagattcctc ctgtgcttta aagtgtgtag gcagaaacca
     1561 gtctggtggt tccggtcagg gagtctgata cctcaacttc ccgggtgact ataaccatac
     1621 ctgactgacg aagtctctgc acatcagctg caattcgctg agttcccagc cagaacaggc
     1681 catccagtgc cgttaccagc aacccgcttt ccagcgccag tttcagccgt gccgtcgggg
     1741 ctttaacctg cccggcgata tcagtaaaac aacgcgtcgt catgccatag cagtccatcc
     1801 gccgtattcg cgtcgcaaga ctgtagctga aacaatccgg cacgccggat aagtcattct
     1861 gcagactgta tacacatccc cgctgccgcc cgttgaacag ggcttttttc tgactgagca
     1921 gccattcccg acgcagagtg tcaatcatct gcggtgtccg ggttaacagc agacgaaacg
     1981 gcagctcaaa actggtcaca taatcaacat tcagtaatgc tgtccgcagt cgctccctgg
     2041 cacctgcccc ggtctcccgg cattcataca tgacatcagc ccactgacgc atcagtcgtg
     2101 gagactcatt cctggccctg aactgatatt tctcaatctg ataatcaata tgttcctgca
     2161 tactgtcacc ggatatctgt tactatatca tcatgaatat tagcctactg gaattcatgc
     2221 gctgcgtgaa gcattacatt accggaaaca taaactcaac ttaacgatat tattccataa
     2281 tataaacgcc gcctgttttt catgaataaa aaaggatgta ataaaatgat aaaatatata
     2341 ttctctctcg ctattatttt ttcaggttcc ctctgcgctg cacagattca gggaaacgtt
     2401 atccgcgttc ttgatggtga tacactggaa atattacagg ataaaaaaac tgtcagggtc
     2461 cgcctggcaa atattgatgc accggaaaag aaacagccct ttggacgctg gtctgcctct
     2521 cagttaaaag acctggtggc cggtaagcct gtaaccgtac aatacttaca gaccgacaga
     2581 tataaccgta ttctcggcag agtctatacc gctgacggca ctgaagcgaa tcgtgagcaa
     2641 atcaggaagg gagcggcctg ggtatacccg gactacaaca aggactatac tctcccggct
     2701 ctccagcgcg atgcccgtgc ccttaaacgg ggattatggg cagatgaaaa tccagtgcca
     2761 ccatgggcct ggaggaaaca gaataaaaaa taatcatttg ctgatatgaa gcaaaaaaac
     2821 atttcaaagc aaataaatgg caaaaataca gtatgggaaa aaattgccat ttttaccgcc
     2881 gcgttatttt taatatttgc tgtctgctgg tcgtaataag caaaataaca gaaaggtgta
     2941 aaaatgaacc tggttgatgc atttgtcact aaagtgatat ccggaccgta tgaagaatac
     3001 ggaaaatggt gggtggatgt agaatatatt tcctggggag ttccggggaa aagccggctc
     3061 atgtttgact cacgggaaca ggcgcaggaa gtgcaggaag gttttcggtt tttaacctga
     3121 gcatatttta ttaaagggca gaaggcggtc cccttctgcc cttaagtacg tttccgggat
     3181 tatctgtcaa ccagttcccg gatcagttcc aggattgcta tcactgcgtt agccacagca
     3241 acaaccgccc tgagaacgat gattaacagg ttaatcatcc gtttctccgt caatggagga
     3301 aatcactgtt gtttactctt acattgcctg tcacaacagc tctttcattg ttagatgtaa
     3361 agtgatttct ctccagccag agcactgaac acagcaccac ctgttcgatc agccaggact
     3421 taaaatctcg cgttcatcgt cccattggag atcacggcag aagcatcacc agacagagct
     3481 aacggagcga ttatagtcat ttttctgatt gcaaaaaaga gaagcgcagc ctactatgat
     3541 ggtgttagat gtagagtgat ttccctttcg gtcagagtca ccaactccgc cccggaatag
     3601 caaaaaaacc gacctcacca gtcggttttt ttgtgcctgt ctctcactgc cttctgctgt
     3661 tcctgtgaaa ataccctggt tatttcatcc ctgcccggtc attaccggcg attgttcgca
     3721 ttaattccac tcagcctcat cccgaaattt atctatttat cgatggagga atcctcgtgt
     3781 cttaccaaca ctcccccaca acagaagacc cgatgaacat atggtatatc gttggcacca
     3841 tatgtctgct ctttgcgctt ctcatctggc tctttttacc tgatatcgtc tttgccacct
     3901 gcctgatcct gcacacaatg tgggggatga ctgactgggg gccttttcac cattttgccg
     3961 ccccccgtta taacctgctg gccaacaccg ccaacaacgc tgcaacgatc actttcagcc
     4021 agtggctgga tgtcatgtca cagaccgtgg ggatcctctg gctgattctg cttcccatga
     4081 cgatcggctt tctgtggatg tggtttcagc atccggccca gccccgcttc acccgcagac
     4141 cactgaatat ccacacgctg ccacacctgt tttcatcact gtcaccggcg atcgcccccg
     4201 ttctggctga cggagacagc aacagactct tccacggaca aaaacgtccc gagcgccgtg
     4261 tcgctctaac cccggaagtc tttgtggcac agaacaacct tatccgcaac atgcggctcg
     4321 atgttgcggc cacgcgccag tgctttatgg cgcaactggg ccagcctctg accacctgga
     4381 aagacatggc tccacatgaa aaagcactct ttgccgtctt tggcctgcag ttcttccttg
     4441 gggaccggaa atcggctgtt tccctgatga ataacctcaa cctctcctgc agactcaaaa
     4501 gcaagcggga ccaggggcgt ttcagcacgc cagtgtattc actggccaga aacgccttta
     4561 tccgggtcat aaaaacagaa gacgcacaac agtggctcag gcaacaccgt tacgttcgca
     4621 gtggtcttgt ctggctttac gcacatgatt tgcgcctgac gccccccaac tggctgtggc
     4681 tcaagggcgt tgaccggacg ctcttctatg cccttcaccg ggcaaacacc acaaaaggct
     4741 tcatcgaagg ggccggcgtg gtggccgttg cccgggcaga aaatgaagcc agccgtctcg
     4801 gcctcccctg cccggaaccc tgtgtggaag aggccattga agggcttcga cgggacatgc
     4861 tggggctggg cctgatatgg gacgaacctc agccagatcg cgatcgtaaa cgtcagatca
     4921 ggacccgctg gtcactcacg gatgacgtga taccccgccg ccatgataac gacgaagaca
     4981 ctgacactgg
//
LOCUS       DAPOXO010000177         4811 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.177, whole genome shotgun sequence.
ACCESSION   DAPOXO010000177 DAPOXO010000000
VERSION     DAPOXO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4811
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.177"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            104..571
                     /locus_tag="ROH59_004948"
     CDS             104..571
                     /locus_tag="ROH59_004948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4807321.1"
                     /translation="MLKTNSLRESMLHGCRWCQANPEKFTIFVESGNIETTGEAPSFV
                     YRYQMVMFVMDYAGELDDLTLPLLAWLSENQPQLLLNPERNQDIKFSAVINDDDSADL
                     LFTLPLRERVRITRNSQGTPQAEHLPEPKPRLPSSEGDWSHVFQDVTWGESDG"
     gene            564..1199
                     /locus_tag="ROH59_004949"
     CDS             564..1199
                     /locus_tag="ROH59_004949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HDX4807322.1"
                     /translation="MDKAFTRVDETFEAIRDSLNQQAINNIARKLAQDLRRAQQARIR
                     SQKAPDGTEWTPRRRRVTRIQERIRFIWNNEARTLKNWHHDTGKYGRTITGWDEDKNN
                     IRTFYRDDIDRFLEIRTRRINQDSTKRVPMFVKLRTARYLKARADASGVTVGYSGVAA
                     RIARVHQFGERDQVAPGIFTDYPVRELLGISQADERLIYNTVLGRIAEAVR"
     gene            1211..1777
                     /locus_tag="ROH59_004950"
     CDS             1211..1777
                     /locus_tag="ROH59_004950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HDX4807323.1"
                     /translation="MRLLSNIIRTGIISEVDEKSWRVRVRSGELETGWLRWNTTRAGA
                     FNVWLPPSPGEQVVIACIGGNPETAMIIGSLWSDASPAPGKSLKEIVVSAPDGAVFRY
                     DADAGALSASGMKTATLQASVSVTLDTPVVECTNLLRTATLDVTKEGKMSGNITHSGG
                     NFTSNGITVHTHKHGGVKGGSDSTGGPQ"
     gene            1795..2124
                     /locus_tag="ROH59_004951"
     CDS             1795..2124
                     /locus_tag="ROH59_004951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001705832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HDX4807324.1"
                     /translation="MNPDGTGNLNDMEHLKQSVRDILITPLASRVMRREYGSLVPDLI
                     DEPMNNTTRLQCMSAAVIALTRWEPRIALDAIDVVWKAGGRAGVTLSGTVMQTMQNVE
                     LTITLRE"
     gene            2128..3024
                     /locus_tag="ROH59_004952"
     CDS             2128..3024
                     /locus_tag="ROH59_004952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDX4807325.1"
                     /translation="MPAVDLSQLPEPAIIAEPDFEAILADTKAMMIASYPAEQREAVS
                     AALELESEPLNVIAQTMSFREMLLRQRVNEGARACMLSHGSGTNLDNLAGNMNTKRLV
                     ITPATDTTDAVMESDTSLRLRAQRAYDGLSVAGPSGAYEYFARSASGLVRDARAISPS
                     PACVTVSILSTEGDGTATEALLNTVRAVLNAEDTRPVADRLTVQSASIVTWRLNAKLY
                     FYPGPESEPILAAAESSFRKWLAEQGLIGQDVALSAIAAALHVHGVQRVEIIEPTQNM
                     AISDIQAARCESFTISEGGRNE"
     gene            3017..3547
                     /locus_tag="ROH59_004953"
     CDS             3017..3547
                     /locus_tag="ROH59_004953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HDX4807326.1"
                     /translation="MSNSLLPPSASNFMRCAEAVGARITDIPVDLNTLWSPDTCPVHL
                     LPYLAWAFSVDRWDRNWPEETKRQVIRDAWLIHRHKGTISALRRAIEPLGYLIRVSEW
                     WEFGGEPGTFTVEVGTLDSGVTEEMYLEMERLIADARPVSRHMTGLNIIQEIQGDIFA
                     AAATYDGEVITIYPDD"
     gene            3550..>4811
                     /locus_tag="ROH59_004954"
     CDS             3550..>4811
                     /locus_tag="ROH59_004954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HDX4807327.1"
                     /translation="MSTTTRKFKTVITDTGAKKLAQAAAPDGKPVRLTHMAVGDGGGT
                     LPTPDSKQTRLVHEVWRHTVNRVILDATHQNRIIAELVIPPETGGFWIREIGVFDEHG
                     DLIAVGNTAESYKPAVAEGSGRAQTFRTILTVSSTATVVLTVDNTMVMATVDYVDDKL
                     KEHEQSRRHPDASLTAKGFVQLSSATNSVSETQAATPKAVKAAYDLANGKYTAQDAST
                     TRKGLVQLSSATNSTSETQAATPKAVKAAYDLANAKYTAQDATTAQKGIVQLSSATNS
                     TSETLAATSKAVKAVMDETNKKAPLNSPALTGTPTTPTARQGTNNTQIASTAFVMAAI
                     AALVDSSPDALNTLNELAAALGNDPNFATTMTNALAGKQPKDATLTALAGLTTAAGKF
                     PYFTGNDVASLATLTKVGRDILAKSTVAA"
BASE COUNT         1178 a         1335 c         1384 g          914 t
ORIGIN      
        1 taactgatat cactaaaaat gccgcgtacg gcgtcgatat cggcagcctg gtgctggaaa
       61 tcaataatcc cgcagcataa ggaagagcag gagagcaaaa cagatgctta agacaaacag
      121 tctgcgagag tccatgcttc atgggtgtcg gtggtgccag gctaatcccg agaaattcac
      181 cattttcgtg gagagcggca acattgaaac gaccggagaa gcgccctcgt ttgtttaccg
      241 ctatcagatg gtgatgtttg tcatggatta cgccggagag ctggacgacc tcacgctgcc
      301 gctgctggcg tggttatccg aaaatcagcc acagttgttg ctcaatccgg agcgtaatca
      361 ggacatcaaa ttttctgccg ttatcaatga cgatgacagc gccgatctcc tgtttacgct
      421 ccccctgcgg gaacgcgttc gcatcacgcg caacagtcag ggcacaccgc aggcagaaca
      481 cctgccggag ccaaaacccc gtctgccttc ttccgaaggc gactggtcgc atgtattcca
      541 ggatgtgacg tggggtgaaa gcgatggata aggcattcac ccgcgtggat gaaacctttg
      601 aggctatccg cgacagcctg aatcagcagg ccatcaataa catcgccaga aagctggcac
      661 aggatttacg tcgcgcccag caggcacgta tccggtcaca aaaagcgccg gacgggaccg
      721 aatggacacc acgcagacgc cgcgtaaccc ggatacagga gcgcattcgc tttatctgga
      781 ataacgaagc acgcacgctg aaaaactggc atcacgacac agggaaatac gggcgaacca
      841 ttaccgggtg ggatgaggat aaaaacaata tccgcacgtt ttaccgggat gacatcgacc
      901 gttttctgga aatacgcacc cggcgcatca accaggacag cacaaagcgc gtccccatgt
      961 tcgtaaaact gcgcaccgcc cgctacctga aagcccgtgc agatgcctcc ggtgtgacgg
     1021 tgggttacag cggcgtggcc gcacgtattg cacgcgttca tcagttcggt gagcgcgatc
     1081 aggttgcgcc gggcattttc accgattacc cggtacgtga gctgttgggt atcagccagg
     1141 cagatgagcg cctgatttat aacacggtgc tgggccggat tgcggaggct gtacggtgag
     1201 cgcagaactc atgcgactgc tgagcaacat catccgcacc gggatcatct ctgaagttga
     1261 tgagaagtcc tggcgcgtgc gcgttcgcag cggcgaactg gaaacaggct ggttgcgctg
     1321 gaacaccacg cgcgcgggag ccttcaatgt gtggctgccg ccatcaccag gcgaacaggt
     1381 ggtaattgcc tgcattggcg gcaacccgga aaccgccatg ataattggca gcctgtggag
     1441 tgatgccagt ccggcccccg gcaaaagcct gaaagaaatc gtggtcagcg cgccggatgg
     1501 cgcggtgttc cgctacgacg cagacgctgg cgcactgagc gccagcggca tgaaaacagc
     1561 caccctgcag gcatccgtca gcgtgacact ggatacgccc gtcgtggaat gcacaaacct
     1621 tctgagaacg gcgacgcttg acgtcacaaa agagggaaag atgagcggca atatcacgca
     1681 cagcggcggc aatttcacct caaacggcat taccgtgcat acgcataagc acggtggcgt
     1741 taaaggtggc agcgattcga caggaggccc gcagtgacaa cccgctacac aggaatgaac
     1801 ccggacggga cgggaaacct gaacgatatg gagcacctga aacagtcagt cagggacatc
     1861 ctgatcaccc cgctggcaag ccgggttatg cgacgggaat atggcagcct tgtgcctgat
     1921 ttgattgacg aacccatgaa taacaccacg cgtctgcaat gcatgagtgc tgccgtgatt
     1981 gcgctgacac gatgggaacc ccgcattgcc ctggacgcca tcgacgttgt ctggaaggca
     2041 ggaggccgcg ccggggtgac gctgtcgggc actgtcatgc agaccatgca gaatgttgaa
     2101 ttaaccatca cgctgagaga gtaaatcatg cctgctgttg atctttccca gttaccggaa
     2161 cccgccatca tcgcggagcc tgattttgag gcaattctgg ctgacacaaa ggccatgatg
     2221 attgcgtcct atcctgccga acagcgtgaa gccgtctccg ccgcgctgga gctggaatca
     2281 gaacccctga acgttatcgc tcaaaccatg tcgtttcgtg aaatgctgtt acgccagcgg
     2341 gttaacgagg gcgcacgcgc ctgcatgtta agccacggtt cagggacaaa cctggacaac
     2401 ctcgcgggca atatgaacac aaagcgcctg gttatcactc cggcaacgga taccaccgac
     2461 gcggtgatgg agagcgacac ctcgctgaga ctgcgggcgc agcgggcgta tgacggcctg
     2521 agtgttgctg gcccgtcagg tgcatacgag tattttgcac gcagcgccag cggtctggtg
     2581 cgtgatgcgc gggccatcag cccgtctccg gcctgtgtga cggtttccat tctgtccact
     2641 gaaggcgacg gcacagcaac ggaggcgttg cttaataccg ttcgcgccgt tctgaatgca
     2701 gaggataccc gcccggtggc cgaccgactg accgtacaga gcgccagcat cgtgacatgg
     2761 cggctgaatg caaaactgta cttttacccc ggcccggaat ccgaacctat tctggctgcg
     2821 gctgaatcgt cgttcaggaa gtggctggct gagcaggggc ttattggtca ggacgtggcg
     2881 ttgtcagcca ttgctgccgc acttcatgtg cacggcgtgc aacgcgtgga gataatcgaa
     2941 cccacacaga atatggccat cagcgacata caggcggcgc gctgtgagtc attcaccatc
     3001 agcgaaggtg ggcgtaatga gtaattcact gttaccgcca tcagccagca atttcatgcg
     3061 ttgcgccgaa gctgtcggag cgcgcattac agacatcccg gtagacctca acacgctgtg
     3121 gtcaccggac acctgcccgg tgcatctgct gccttatctc gcctgggcat tttccgttga
     3181 ccgctgggat cgcaactggc cggaagagac aaagcgacag gtgattcgtg atgcatggct
     3241 gatacaccga cacaaaggga ccatcagcgc actgcgccgg gccattgagc cgctgggata
     3301 cctcattcgc gtgtctgagt ggtgggagtt cggcggagaa ccgggaacat ttaccgttga
     3361 agtcggcacg ctggacagtg gcgtgacgga ggaaatgtat ctggaaatgg agcggttgat
     3421 tgctgatgcc cgcccggtca gccgccacat gacagggctg aatatcattc aggagattca
     3481 gggagatatt ttcgcggcgg cagcaactta cgacggcgaa gtcattacca tttatccgga
     3541 cgattaagca tgagtaccac aacacgtaaa tttaaaaccg ttatcaccga tacgggtgcc
     3601 aaaaaattag ctcaggcagc cgcgccagat ggtaagcctg tccgcctgac tcatatggcc
     3661 gtgggcgacg gtggcggcac gttgcccaca ccagacagta agcagacccg tctggtgcat
     3721 gaggtgtggc gacatactgt taatcgcgtc atcctggacg caacacatca gaaccgcatt
     3781 attgcggagc tggttattcc tcctgaaacg ggcggattct ggatccggga aattggtgta
     3841 tttgatgagc acggcgattt aatcgcggtg ggcaatactg ccgaaagtta caagccagcc
     3901 gttgccgaag ggtccggtcg tgcacaaaca tttcgcacca ttctgaccgt atccagcact
     3961 gccaccgtgg tgcttaccgt ggataacacc atggtgatgg ccacagtgga ttacgtggat
     4021 gacaaactga aagagcatga acagtcacga cgtcacccgg acgcctcgct gaccgcaaaa
     4081 ggctttgttc aactcagtag cgccactaac agcgtgtctg aaacgcaggc tgcaacgccg
     4141 aaagcagtaa aggccgcgta tgaccttgct aacggtaaat atactgcgca ggatgccagc
     4201 acgacgcgaa aaggccttgt ccagctcagt agcgccacca acagcacgtc tgaaacgcag
     4261 gctgcaacgc cgaaagcagt aaaggccgcg tatgaccttg ctaacgcaaa atataccgct
     4321 caggacgcca cgacggcaca aaaagggata gtccagctca gtagtgccac caacagcacg
     4381 tctgaaacac tggccgcgac atcgaaagct gttaaggcgg taatggatga aacgaacaag
     4441 aaagcgccct taaatagtcc tgcactgacc ggaacgccaa caacaccaac tgcgcgacag
     4501 ggaacgaata atacccaaat cgcaagcacg gctttcgtta tggctgcgat tgccgccctt
     4561 gtagattcgt cacctgatgc actgaacacg ctgaacgagc tggctgcggc gctgggcaac
     4621 gacccgaatt ttgcgaccac catgactaac gcgcttgcgg gtaagcaacc gaaagatgcc
     4681 accctgacgg cgctggccgg acttactact gcggcaggca agtttccgta ttttacgggg
     4741 aatgatgtcg ccagcctggc aaccctgaca aaagtcgggc gggatattct tgcgaaatcg
     4801 accgttgctg c
//
LOCUS       DAPOXO010000178         4800 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.178, whole genome shotgun sequence.
ACCESSION   DAPOXO010000178 DAPOXO010000000
VERSION     DAPOXO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4800
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.178"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(63..326)
                     /locus_tag="ROH59_004955"
     CDS             complement(63..326)
                     /locus_tag="ROH59_004955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4224 domain-containing protein"
                     /protein_id="HDX4807328.1"
                     /translation="MKSDHDIITREEMVELTGSPLKSKQCEALRRAGIFFMERADGHP
                     KTTWGHFMNPIKFRNLQEVTTRKDDEPDFGAIFNGRKEKEPSR"
     gene            complement(536..718)
                     /locus_tag="ROH59_004956"
     CDS             complement(536..718)
                     /locus_tag="ROH59_004956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807329.1"
                     /translation="MLKLTLKRGDAVHLVLADGTNGIIEARSRCELGLHLPENIKVTR
                     EKSAFTPQELITPNQK"
     gene            complement(718..1287)
                     /locus_tag="ROH59_004957"
     CDS             complement(718..1287)
                     /locus_tag="ROH59_004957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HDX4807330.1"
                     /translation="MSTAIAIAKEYASLIDLLETADELTPEMIADTLEGMEGELGDKL
                     DAMMVICRNLQGNANTCAEEMSRLATRKTSFEGKEKAIRKHMLTCLQAAGLDKLKTAK
                     NTFTDAQGAIRVIIDSKDKIPDEYEGVSLVDVETVITPNKRAIKEVIESAEAVAAEIL
                     ARGETPPAELLNPVPGAHLERGERSLRIR"
     gene            complement(1284..3500)
                     /locus_tag="ROH59_004958"
     CDS             complement(1284..3500)
                     /locus_tag="ROH59_004958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807331.1"
                     /translation="MTIFNGLLEAKKGALKNGAIPALAIAIAAPNKKVAENIIIGKLW
                     EAYPDHGDNYFKPKIWEDAPGQPRPGVGEFDETFATEHSFDGEKWVVNTPVDSDCSSA
                     DISQVSDLMKLPARERFAAVLLFSHDANEVDSELLVQTREYLEMLDNSDTDSEDEVDA
                     FNRIVLDAMVACKPIEYMHIAGLNNLVHAILASCDTQEQNPTSWTISKFIKKWVENPG
                     KRDEMLPEVKPETASARPYKQTHATLDREIACALLPVAPEKITPSILKAADEIISQDR
                     EDFKRWSMALRTTDQILAYDRASVFGVIQSAPAKDTYHFPQSLRSHIDNWLQANGQRD
                     ANAVEEKPKEAAPKDDVKVTNHGGGRFSIDGMMSETPSNQGEKSEAANAGERSLQQLR
                     EQFVTPRHVYDVPENNAVSQREPAAITLAEETPPQEQLSEQVKDLVQNVDALVERIHA
                     EEHKRQNAISAIETELKDSDDTDNLALWKNVFKTDERFTSAFSQNGGGTSINGTYIAM
                     KATREFGPFGIGWGVEVLEERFDKGAPIVRKKQVGEKIEWDLIQDGVGGYLCEMHHTM
                     KVRVWYILNGVRGESEAYGCTPYIYDTKYGPTSDGEAPKKSWTDAVKKALSPLGFSAD
                     IFMGLYDNPEYRQRNKAEFDIKNASENAEDATRLRKELDEKLINVANTLAAAVTANEV
                     NKVFGLIAREVDVHRKAAETKGDKEYSSYLGSRLRRITDIKTERLAALTAAQEQTA"
     gene            complement(3531..3851)
                     /locus_tag="ROH59_004959"
     CDS             complement(3531..3851)
                     /locus_tag="ROH59_004959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807332.1"
                     /translation="MEARTIPVTLFIHYATSTFSHEKLLVATVDMSKNFPDRYILLES
                     REIEITVNQPEPIDIIGLQVEQLREQKQKTVADAQQRIAAIDDKIQQLLCIEYTPDTD
                     ELPY"
BASE COUNT          975 a         1199 c         1195 g         1431 t
ORIGIN      
        1 tgttatcttt attcctgaat tcgtaggccg ctttgccctg gtaaacacga ggcggcatcc
       61 agttatctgc tgggttcttt ctctttccgg ccattaaata ttgctccaaa atcaggttca
      121 tcatcttttc gcgtcgtcac ctcctgtaaa ttgcgaaatt ttattgggtt catgaaatgg
      181 ccccaggttg tttttgggtg tccgtcagcc ctttccatga agaaaattcc agcccggcga
      241 agagcctcac attgctttga tttaagtggg cttcccgtca gctcgaccat ttcttctctg
      301 gtgattatgt cgtgatcgct tttcatggtc tttcctcatt atgtagctta ttgcgtcatc
      361 tgccttctgg caggcacggg caatatcaga ctcggtcaaa gtctgtttcc tgacgctggc
      421 cgacagtcga ccaattttga tatcaaatgc ggagagcaga gttgctcccg gttgccatcg
      481 cagcattgtg atcctccggt gtctggtgaa tcgcaatgct agcgatggtg agtttttatt
      541 tctgattagg cgtaatcagt tcttgtgggg tgaatgccga tttctcccga gtgaccttaa
      601 tgttttctgg caggtgtagc ccaagttcgc agcggctccg tgcttcaata atgccattgg
      661 taccatcggc aagtaccagg tgaaccgcgt caccacgctt taatgtgagt ttaagcatta
      721 gcgtatcctc agtgaccgtt cgccgcgttc cagatgtgcg cctggtaccg ggtttaataa
      781 ctcggctggt ggtgtttctc cacgcgccag tatttcggcg gcaaccgcct ccgcagattc
      841 aatcacttct ttaatggctc gcttgtttgg tgtaataacc gtttctacat caacaagtga
      901 cacgccctca tactcatccg ggatcttatc tttgctatcg ataattaccc ggatagcccc
      961 ctgtgcatca gtaaatgtgt tttttgcggt tttcagttta tccaggccag cagcttgcag
     1021 gcaggtgagc atatgctttc gaattgcttt ttccttgcct tcaaaggacg tcttacgggt
     1081 tgccaggcga gacatttctt cagcgcaggt attggcattg ccctgtaaat tacggcagat
     1141 gaccatcatg gcgtccagtt tgtctcccag ttctccttcc atgccttcaa gcgtgtcggc
     1201 gatcatctct ggcgtcagtt catcggcggt ttctaacagg tcaatcagac tggcatattc
     1261 ttttgcaata gcgatagcag tgctcatgct gtttgctcct gtgcagcggt aagggcggcg
     1321 aggcgttcag ttttaatgtc ggtgatacgg cgcagacgtg atcccagata cgatgaatat
     1381 tctttatcgc ctttggtttc cgctgctttc ctgtgtacat ccacttcgcg ggcgatgagg
     1441 ccaaatacct tgtttacttc gttggcggtt accgcggcgg ccagcgtatt ggcaacgttg
     1501 ataagcttct catccagttc cttacgcaga cgggtagcat cttccgcatt ctcgctggca
     1561 ttcttgatat caaactcagc tttattcctc tggcggtatt ccggattgtc gtacaggccc
     1621 atgaaaatat cggcgctgaa tccgagaggg gatagcgctt tcttaacagc atccgtccag
     1681 gatttcttcg gtgcttcgcc gtcgcttgtt ggtccgtatt tagtgtcgta gatataaggt
     1741 gtgcatccgt aagcctcgga ctcaccgcgt accccattca atatgtacca gactctcact
     1801 ttcatggtgt ggtgcatttc acataggtac ccgccaacac cgtcttgaat cagatcccat
     1861 tctatttttt caccaacctg ttttttgcga actattggtg cgcctttatc aaagcgctcc
     1921 tccagcacct ctacccccca gccaatacca aatggcccaa attcgcgagt cgctttcatc
     1981 gctatataag tgccgttgat ggatgtgccg ccgccattct gagagaaagc actggtgaag
     2041 cgctcatcgg ttttgaatac gttcttccac aatgccaggt tatccgtgtc atctgagtcc
     2101 tttaactccg tttcgatagc tgagattgca ttctgccgct tgtgctcttc ggcatggatc
     2161 cgctcaacca gcgcgtcaac gttctgcacc agatccttta cctgctcgct aagttgttct
     2221 tgtggaggag tctcttctgc cagggtaata gctgcaggtt ccctctgtga tacggcgtta
     2281 ttttcaggta cgtcatacac atggcgaggc gtgacaaact gctcacgcaa ctgctgcaaa
     2341 ctacgttctc cagcatttgc agcttcgctt ttttcgccct gatttgaggg tgtttctgac
     2401 atcatcccat caattgagaa tcgtccgccg ccgtggttgg tgacttttac atcatccttg
     2461 ggtgctgctt cctttggctt ctcttcaaca gcatttgcat cacgctgccc gttagcttgc
     2521 agccagttgt cgatgtgact gcgcagggat tgtgggaagt ggtacgtgtc ttttgcgggg
     2581 gcgctctgaa taacaccgaa tactgatgcg cggtcatagg caaggatctg atccgttgtg
     2641 cgcaaggcca ttgaccagcg tttaaaatct tccctgtcct gactgattat ttcgtctgcc
     2701 gctttcagga tgctgggggt gattttttcc ggggcaacag gtaacagggc gcaggcaatt
     2761 tcacgatcca gagtggcgtg agtctgtttg taaggacgtg cggatgctgt ttctggtttt
     2821 acctccggca gcatttcatc tcgtttaccg ggattctcta cccatttttt tataaatttg
     2881 gagatagtcc aactggtcgg gttttgttcc tgggtatcgc aacttgccaa aattgcatgt
     2941 accagattat tcaatccagc aatatgcatg tactcgatgg gcttacacgc caccatggca
     3001 tcaagaacga tgcggttaaa cgcgtcaacc tcatcctcac tgtcagtatc actgttatcg
     3061 agcatctcca ggtattcacg cgtctgcaca agcaattcac tgtcgacttc gttggcgtcg
     3121 tggctgaaca gcagaacggc ggcgaatcgt tcacgagccg gcagtttcat caggtcgcta
     3181 acctgtgaga tatctgctga actgcaatct gaatcaacag gagtgttaac tacccatttt
     3241 tcgccatcaa aactgtgttc tgtggcaaac gtctcatcaa actcaccgac gcctgggcgc
     3301 ggttggcccg gggcatcttc ccagatttta ggtttgaaat agttgtcgcc gtggtcaggg
     3361 taggcttccc acaatttgcc gatgatgatg ttctcggcaa cttttttgtt aggggcggcg
     3421 atggcgatgg ccagcgccgg gatcgcgccg tttttgagcg cgcctttttt cgcttctaac
     3481 aagccgttaa aaatggtcat tggtctttcc tcattacagg tcagtggttt ttagtagggg
     3541 agctcatcgg tatctggcgt gtattcgatg caaagtaact gctggatttt gtcatcgata
     3601 gcagcaatac gctgttgggc gtcggcgact gttttctgtt tttgttcacg cagttgctcg
     3661 acctgtaaac cgatgatgtc gattggctcg ggctggttaa cggtaatttc aatttcgcgg
     3721 ctttccagaa ggatgtacct gtctggaaaa ttttttgaca tatcaacagt cgcaacaagc
     3781 agcttttcgt ggctgaaagt tgaagttgca taatgaataa agagtgttac tgggatggtg
     3841 cgcgcttcca tagcgactcc ttggtaatgt atactcagag ccgatcagcg aatattgatc
     3901 agcttccata gcgtcagtgt cgttggtctt tcctcatcac aagtttggtc acttgtgata
     3961 aatccgaatg gtttggtcgc cgttcggggt aactggcccg ccttgtgcgg gtcttttgct
     4021 atctaaaggg tgccggttac gtttccggcg tcgttatgtt tccattacga ccgtacaggg
     4081 ctggtcaggc ccgggctggt ctttcctgtt ttgagctggt caggctcatg gtcaacgctg
     4141 gtcaggcgtg gtacttcctc cggtctttcc ctggtgtcac gctgcgggtt tggcctctcc
     4201 tgttggggac tcaggcacag cgataaaacc tggctgtgtg aaaaaatggc ccatcgtgcg
     4261 gactgggcaa agactaaaca cagcaaattg atgatgggcg cccggaatcg aaccgggtaa
     4321 cgggcaggga gttcccgtta aacacctgtt caccacaacc gggagcgcac tccgccattt
     4381 caaaatttaa cgacaaagct caaagttgag tcgatgaagt gcgctctcgt gttgtagcca
     4441 ggactcttcc ctggtggtca caccgtatcg ccttgatggt gaatcaatcg ctcatacctg
     4501 gctgtggctt gcacattccg gctacctgct atggagacaa cgcgttaagg ctccgcttcc
     4561 atccagaccg cttcgacaca tgtgccatat gccggtgaag tctttccctc tgtcaccgtg
     4621 ttggcgccga cgcgcaaaat ttggtgccgt ctttccggct gtcagaacgt gtttctgaac
     4681 aactgccgct gggtaagcgt tgttgatgaa agtgacttta caatttgtat ttgtaatggt
     4741 caatgtgttt ttaaaaaata atttgtagtg aggggcaaaa aaatattcac tgtgtaaagg
//
LOCUS       DAPOXO010000179         4626 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.179, whole genome shotgun sequence.
ACCESSION   DAPOXO010000179 DAPOXO010000000
VERSION     DAPOXO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4626
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.179"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..570)
                     /locus_tag="ROH59_004960"
     CDS             complement(<1..570)
                     /locus_tag="ROH59_004960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4432 domain-containing protein"
                     /protein_id="HDX4807333.1"
                     /translation="MSTRIYLWRALFGEKPRILLENSDFTVTSFRYDSGVEGLKIANS
                     RGHLIILPWMGQMIWDAQFDGHSLTMCNMFRQPKPATEVIETYGCFAFHSGLLANGCP
                     SAEDTHLLHGEMACAAMDEAWMELEGDMLRLTGRYEYVMGFGHHYLAQPTVVLHRSST
                     LFDIKMAVTNLASVDMPLQYMCHMNYAYIP"
     gene            complement(582..1898)
                     /gene="fucP"
                     /locus_tag="ROH59_004961"
     CDS             complement(582..1898)
                     /gene="fucP"
                     /locus_tag="ROH59_004961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDX4807334.1"
                     /translation="MNDKNIIQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIGGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     ASGILLGKYLVFSEGESLEKQMSGMNAEQIHNFKVLMLENTLEPYKYMIMILVVVMVL
                     FLLTRFPTCKVAQTSHHKRPSAMDTLRYLAKNSRFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASNFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNQHTEMAGAVIVMAIVGAAVVPA
                     IQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRNALAEVTES"
     gene            complement(1926..2846)
                     /gene="rbsK"
                     /locus_tag="ROH59_004962"
     CDS             complement(1926..2846)
                     /gene="rbsK"
                     /locus_tag="ROH59_004962"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDX4807335.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHAIEFGKKNGIEVL
                     LNPAPALRELDMSYACKCDFFIPNETELEILTGMSVDTYDHIRLAARSLVDKGLNNII
                     VTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAA
                     LFAAFSVTGKGTQSSYPSIEQFNEFLTLNE"
     gene            3152..3934
                     /locus_tag="ROH59_004963"
     CDS             3152..3934
                     /locus_tag="ROH59_004963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDX4807336.1"
                     /translation="METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLHQ
                     EDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAAGMVNENDLIFFDN
                     GQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNS
                     SPLDSLNPRKIFISASGVHNHFGVSWFNPEDLATKRKAMNRGLRKILLARHALFDEVA
                     SASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE"
     gene            complement(3936..4162)
                     /locus_tag="ROH59_004964"
                     /pseudo
     CDS             complement(3936..4162)
                     /locus_tag="ROH59_004964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229544.1"
                     /note="with IlvB catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase small
                     subunit; frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
BASE COUNT         1370 a         1096 c          933 g         1227 t
ORIGIN      
        1 tggtatatat gcataattca tgtggcacat atattgtagt ggcatatcta cagaagccag
       61 attggttacg gccatcttaa tatcgaacaa tgtagaggat ctgtgaagga ccactgttgg
      121 ctgagccaga taatgatgcc cgaaccccat tacatactcg taacgcccgg taaggcgtaa
      181 catatctccc tctaattcca tccatgcttc atccatcgcg gcacaggcca tttcaccgtg
      241 tagcagatga gtatcttccg cagatgggca gccattagcc agcaaacctg aatgaaaggc
      301 aaaacagcca taggtttcta tcacctctgt cgccggttta ggctggcgaa acatattgca
      361 catggtgaga ctgtgtccat caaattgcgc atcccaaatc atctgcccca tccagggaag
      421 aataattaaa tgtccacgac tgtttgcaat tttaagcccc tcgacaccac tgtcatagcg
      481 aaaagacgtg acagtaaaat cactattttc cagcaagata cgaggttttt cgccaaaaag
      541 cgcccgccac aaataaatac gcgtactcat aacgattctc ctcaggactc tgtgacttca
      601 gccagtgcat tacgtacttt gctttcacgc cagaagtaga caccgacata gacaaaacag
      661 agcatagaaa ccaggaatga aagctgtagt gagtggaaca tatctgcaat atacccctga
      721 attgccggaa ccaccgctgc gccaacaata gccataacaa tgactgctcc tgccatttct
      781 gtatgttgat tatcaactgt atccagtgtt cctgcataga tcgtcgccca gcaagggcca
      841 aacaaaacac ttaccaggac ggcgacatag accgcgctga aacttggagc cagtgcaaca
      901 tatgccagaa acagcgcccc tataacggaa tagagaatta ggactttttc cggattaaaa
      961 cgtgtcataa ggatgttggc tataaacttg ccaataaaga agcaggcaaa gctgtagacc
     1021 atgaagtttg aagcatcacg ttcgttgata tcgcccaact ccagtgccag acggatggta
     1081 aatgaccata ctgcgacctg catacccaca taaaggaatt gagccacaat accacgacga
     1141 aagcgcgaat ttttagccag atagcgcagc gtatccattg ctgacgggcg tttatggtga
     1201 cttgtctgtg ccactttaca ggttgggaag cgggttaaaa ggaacaacac catgaccaca
     1261 accagaatca taatcatata cttatacggt tcaagggtgt tctctaacat cagcacctta
     1321 aagttgtgaa tttgctcggc gttcattccg gacatctgct tctcaaggct ttccccctcg
     1381 gagaaaacca gatatttgcc caataaaata ccagacgcag caccaatcgg ataaaaggtc
     1441 tggctgatat tgagccgcaa tgtggcatag gcttttggac cgatcattga actgtatgtg
     1501 ttcgctgcag tttcaaggaa actcaggcca atcgcaatcg caaaaatagc tgcaaggaac
     1561 atagtgtagg ttgccatatg cgaggcaggg aaaaaaagtg tacaaccacc aatatacagc
     1621 gtcaggccaa ttaaaattgc caccttataa ctggtctttt taatcacaag ggatgctggt
     1681 attgcaatta aaaaataacc tccataaaat gcgctctgca ccaatgctga agcaaagtta
     1741 cttagcgaaa atacactttt gaattgagtg attaatatgt catttaatgc agctgcgcat
     1801 ccccatagcg ggaataaaca cgataacaaa ataaactgga acaagggagt cttattcaga
     1861 tacccatcag gcatctgaat gatgttttta tcgttcatag tgctaccttt aactgtgcag
     1921 gatgattatt cgtttaaggt taaaaattca ttaaattgtt caatactcgg ataagatgat
     1981 tgcgtacctt tccctgtgac gctgaaagcg gcaaagagag cggctttttt caaagcggct
     2041 tcaacatcac cgctttgaac ataataatgg gaaaagcaac caataaatgc gtcaccagcg
     2101 ccactagtat caacagcatt tactttgaat gcaggaacat ggacttcctg atcgcgggtc
     2161 atccataatg cgcctttttc gctcatggta acaataatat tgttcagccc tttatcaact
     2221 aacgaacgtg cggccaaacg aatatgatca taagtatcaa ccgacatacc ggttaatatt
     2281 tccagttctg tttcattcgg gataaagaaa tcacatttgc aggcataaga catatctaac
     2341 tcacgcaatg ccggagccgg atttaataac acttcaatac catttttctt accaaactca
     2401 atcgcgtggt aaactgtttc cagttgaact tccagttgta aaacgatcaa tttgcatttt
     2461 ttcagatctt ctgcagctcg atcgatatct tccggggaaa gaaatttatt cgctccctta
     2521 attattaata tactattgct cgagttggca ttaacaaaga tcggtgcaac accactgctg
     2581 gtacagggga ccttctcaac ataagtggta ttaattcccc atgattcaag attacgaata
     2641 gtattatccg caaaaatatc atcacctact ttagtcagca tcaggacttt tgaattcaat
     2701 ttagccgccg ccaccgcttg attagcacct ttcccaccac atccgatttt gaaggcaggt
     2761 gcttccagag tttctccttc tttaggcatc tgattagtgt aagtaatgag atccaccata
     2821 ttggaaccaa taactgcaat gtccatttca ctacctctta taaactttcg cataacaatg
     2881 gtatttaaat aacattagca tgttactttt gcatcatttg tgactgagat cgcgattagc
     2941 acatcaaccc gatgtttatt taatagactt ccagtctcat cactcaggcc aacactatct
     3001 aatcataagc aacctaacaa gattagtgcc caaaactcag cagcctatac ccttttcatt
     3061 tcaaaggggc ggtcgtatag tatggtaatg aaaacaatgt ttactaacgc caaaatgtta
     3121 tttttataac attcttacgg agagagagtt gatggaaacg aagcaaaaag agcgtatccg
     3181 acgtttgatg gaactgctta agaaaaccga cagaatccat ttgaaagacg cagcgcgaat
     3241 gctggaagtt tctgtaatga ctattcgtcg cgatctccat caggaagatg aacctctgcc
     3301 actgacccta ctgggtggct atattgtaat ggtgaataaa cccgcgccat ccatgccagt
     3361 aatccatgac gttccaaaaa atcatcgtga tgacttacct attgcaattc tggctgccgg
     3421 aatggttaat gaaaatgatc tgatcttctt tgataatggc caggagatac cactcgttat
     3481 aagcatgatt ccggatgcaa tcaccttcac cggcatctgt tactcacatc gcgtctttgt
     3541 tgcgttgaat gaaaagccta atgtaacagc aatactttgt ggtggtacgt atcgtgccag
     3601 aagtgatgct ttttacgatg ccagtaactc ttcgccatta gactctctca atccgcgaaa
     3661 aatatttatt tccgccagcg gtgtgcataa tcactttggc gtcagctggt ttaaccctga
     3721 agatcttgcc actaagcgta aagcgatgaa ccgtggacta cggaaaattt tgctcgcccg
     3781 ccacgcgttg ttcgatgaag tggcctctgc cagcctcgca ccgatctctg catttgacgt
     3841 tctgattagc gatcgtccgt taccggcaga ttatgttacg cactgccaga atggttctgt
     3901 aaagatcatt acacctgatt cagaagacga atgacttact gaaaaaacac cacaatcttg
     3961 ttaaacatcg tcgggttgga ctgattacgt tgcactttca ccacatattc cagcttatct
     4021 atttggctta tcacctactc cagacgctgg tcatccttga ccagtagcca gatatggctt
     4081 ttgtcgcagt cctgaatcgg caggcagaga atgtcttcaa cgttaagagc gcgacgggca
     4141 aaagcccaca aaggtgagtc attacacccg gatggtaaac aggcacttcc ttgttgtaga
     4201 agccgttata ttgtccataa tgtatgggtt tttaatgcat actgggtaac aaccggacga
     4261 atcttcgaat atcactggcg ctgccagccg gtttgaattc atctcacaac cctgcataga
     4321 gcgaatctcc tgcctgcacg tcactccact ccatggtatc aacttcacac tctttatctg
     4381 cggctagctt cagccaccag ataagcatcg actatgaaag atgagccatg acaacataac
     4441 gttggtaacg ctctgacgcc ttaatggaag atgcctgcca ccatagggaa tgtaaacgac
     4501 tgaagtgtgg cctttaatgc cgtgaacggc tcatggtttc ctggcacggt tgccgcccca
     4561 acctgtaaca acattccaca gtacaatgtc tgtcagagtc agagcctccc atgcttgttg
     4621 tagtaa
//
LOCUS       DAPOXO010000180         4625 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.180, whole genome shotgun sequence.
ACCESSION   DAPOXO010000180 DAPOXO010000000
VERSION     DAPOXO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4625
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.180"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            31..1155
                     /locus_tag="ROH59_004965"
     CDS             31..1155
                     /locus_tag="ROH59_004965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004031782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbC family protein"
                     /protein_id="HDX4807337.1"
                     /translation="MTIHYTATLNNKHLSLTALYPDGNREVIAILPVTELGALINRNN
                     RLMHLSFSSPFREITETVLVDTVDAERPGHHIGRMLSAIDACLDAEYAGKGKHPSRKY
                     GFWRTLMCGFIAGIALPATVAGYHWMKAEPPSTLAYPTSQEWRAEPVTDTETPRPHTE
                     HHVNSIPARPAPTQQEPSSTPAPTAVTEEQHVQAAEARRNLATVLKRNADRGMFTINL
                     STGHERTLYAFLDPACINCRLLEPALKQLAREFSVVIYPVSVIGGESSTKRTAPLLCE
                     PDSQKRATGWHQLYSADSGMAPTGDASAAQDGQCLTAARAAIDVNNQAFRQFGFGGTP
                     WVLSDTGWHLPSGILKDATSVRLFLKATDSEEYHNEPAPR"
     gene            1136..3439
                     /locus_tag="ROH59_004966"
     CDS             1136..3439
                     /locus_tag="ROH59_004966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HDX4807338.1"
                     /translation="MSQHHVNPDLIHRTAWGNPLWNALHNLNITGLCLAGSIITALIW
                     PLALPVCLLFTLVTSVIFMLQRWRCPLRMPMTLSLDDPSQDRKVRRSLFSFWPTLFQY
                     EADETSPARGIFYVGYRRINDIGRELWLSMDDLTRHVMFFATTGGGKTETTFAWLLNP
                     LCWGRGFTFVDGKAQNDTTRTIWYLSRRFGREDDIEVINFMNGGKSRSEIIQSGEKSR
                     PQSNTWNPFAFSTEAFTAETMQSMLPQNVQGGEWQSRAIAMNKALVFGTKFWCVRERK
                     TMSLQMLREHMTLEGMAKLYCRGLDDQWPEEAITPLRNYLQDVPGFDMSLVRTPSAWT
                     EEPRKQHAYLSGQFSETFTTFAETFGDVFAADAGDIDIRDSIHSDRILIVMIPALDTS
                     AHTTSALGRMFITQQSMILARDLGYRLEGTDAQTLEVKKYKGRFPYICILDEVGAYYT
                     DRIAVEATQVRSLEFSLIMTAQDQERIEGQTSATNTATLMQNAGTKFAGRIVSDDKTA
                     RTVKNAAGEEARARMGSLQRHDGVMGESWVDGNQITIQMESKIDVQDLIRLNAGEFFT
                     VFQGDVVPSASVYIPDSEKSCDSDPVVINRYISVEAPRLERLRRLVPRTVQRRLPTPE
                     HVSSIIGVLTAKPSRKRRKNRTEPYRIIDTFQRRLATAQTSLDLLPQYDTDIESRANE
                     LWKKAVHTINNTTREERRVCYITLNRPEEEHSGPEDIPSVKAILNTLLPLEMLLPVPD
                     LTASPPHKKNVAQTPSGGKQESRKKRF"
     gene            3906..4136
                     /locus_tag="ROH59_004967"
     CDS             3906..4136
                     /locus_tag="ROH59_004967"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807339.1"
                     /translation="MKTNMGSTKNGARVPHVLNRFTSMDIDMNSQLLPDMLINFALIN
                     ITDRKNEGTNTIDGNWQADERRRYRDNVRIYF"
     gene            4166..4625
                     /locus_tag="ROH59_004968"
                     /pseudo
     CDS             4166..4625
                     /locus_tag="ROH59_004968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase NikB"
BASE COUNT         1214 a         1273 c         1156 g          982 t
ORIGIN      
        1 acagcatccc gccgacaagg aaaaagaaca atgaccatcc actacactgc aacactgaat
       61 aataaacacc tgtccctgac cgccctgtac cctgacggta atcgggaggt gattgccatc
      121 ctgccggtca cagaactggg cgcactgatt aaccgtaata acaggctgat gcacctgtcc
      181 ttcagttccc cttttcgcga aataaccgaa acggtgcttg ttgataccgt tgatgcagaa
      241 cgtcccggac atcacatcgg cagaatgctc tcagcgattg atgcctgcct ggatgccgaa
      301 tatgccggaa aaggaaaaca tccctcccgg aaatatggct tctggcggac actgatgtgt
      361 ggctttatcg ccggaattgc tctgccggcg acagttgcag gttaccactg gatgaaggca
      421 gagccccctt ccacgctggc ttaccctaca tctcaggaat ggagagctga accagtaacc
      481 gacacagaga caccacgccc acatacggaa catcatgtta acagcatccc ggcccgcccg
      541 gctcccacac agcaggaacc ttcttctacc cccgccccga cggcagtgac ggaagaacaa
      601 cacgttcagg ccgctgaggc ccgccgtaat ctggccacag tacttaaacg caacgcagac
      661 cgggggatgt tcaccattaa cctgtccact ggtcatgaac gcacgctgta cgccttcctt
      721 gaccccgcat gcatcaactg ccgtctgctg gaacccgcgc ttaagcaact ggcccgggaa
      781 ttcagcgtgg tgatttatcc ggtctccgtg attggcgggg agtccagtac aaagcggact
      841 gctccgctgc tgtgtgaacc ggactcacaa aaacgggcga ccggatggca tcagctgtat
      901 tccgctgaca gtggtatggc ccccaccggc gatgcatcgg ccgcacagga tggacagtgt
      961 ctgaccgccg cacgtgctgc catcgatgtc aataaccagg ctttccgcca gttcggtttt
     1021 ggcggaaccc cctgggtgtt atcagatacc ggctggcacc tgccgtccgg catcctgaaa
     1081 gacgccactt ccgttcgcct cttcctgaaa gcaacagata gcgaggagta tcacaatgag
     1141 ccagcaccac gttaatcctg acctcataca ccgcacggcc tggggaaacc cgttgtggaa
     1201 tgcactgcat aacctgaaca tcactggtct gtgtctggcc ggcagtatca ttacggcgct
     1261 gatatggcca ctggcccttc ctgtctgcct gctgttcacc ctggtcacct ccgtgatatt
     1321 catgctgcaa cgctggcgat gccccctgcg tatgcccatg acactcagcc ttgatgaccc
     1381 ctcccaggac agaaaggtca ggcgaagcct cttcagcttc tggcccaccc tgtttcagta
     1441 tgaagcagat gaaacatccc ccgcacgggg gattttttat gtcggttacc gccgtatcaa
     1501 tgatatcggt cgtgagctct ggctgagcat ggatgacctc acccggcatg tcatgttttt
     1561 tgccaccacc ggtggcggta aaacagaaac cacctttgcc tggctgctca acccgctctg
     1621 ctggggaaga ggctttacct ttgttgacgg aaaggcacag aacgatacca cgaggacaat
     1681 ctggtatctc tcccgacgtt ttggccggga ggatgatatc gaggtcatca acttcatgaa
     1741 cggcggaaaa tcccgcagtg aaatcattca gagcggcgaa aaatcccgcc cacagtcaaa
     1801 cacctggaac ccgttcgcat tcagcaccga agccttcacc gccgaaacca tgcagtccat
     1861 gctgccccag aacgttcagg ggggagaatg gcagtcacgg gcgatagcca tgaacaaagc
     1921 cctggtcttt ggcacaaaat tctggtgcgt ccgggaaaga aaaaccatgt ccctgcagat
     1981 gttacgggaa catatgacgc tggaagggat ggcaaaactc tattgccgtg gccttgatga
     2041 ccagtggccg gaagaagcta tcacaccact gcgaaactac ctgcaggatg tcccgggatt
     2101 cgatatgtca ctggtgagaa cgccgtcagc ctggactgag gagccccgta aacagcatgc
     2161 ttatctctcc ggtcagttct cggaaacatt cacaaccttt gccgaaacct tcggggacgt
     2221 ctttgcggca gatgccggcg acatcgatat tcgcgacagt atccacagcg accgaattct
     2281 gattgtgatg atccccgcac tggacacatc agcccatacc acgtcggcac tcggtcgtat
     2341 gttcatcacc cagcagagca tgatcctcgc ccgtgacctg ggctaccgcc tggaaggcac
     2401 agacgcacag accctggaag tcaaaaaata caaaggccgc ttcccctata tctgtatcct
     2461 tgacgaagtc ggtgcctact acacggaccg cattgcagtg gaggccaccc aggtacgttc
     2521 actggagttc tccctgataa tgacggcgca ggatcaggag cgaatcgaag ggcagacttc
     2581 tgccaccaac accgccacgc tgatgcagaa cgccggcacc aaattcgccg gacgcattgt
     2641 cagtgacgac aaaacagcaa ggacggtgaa aaatgccgcc ggtgaagagg cccgcgccag
     2701 aatgggcagc ctgcagcgcc acgatggtgt gatgggtgag tcctgggtgg acggtaacca
     2761 gatcacaatc cagatggaaa gcaaaatcga cgtgcaggat ttgatcagac tgaatgccgg
     2821 tgagttcttt accgttttcc agggggatgt ggtgccgtca gcctctgtgt atattccgga
     2881 cagcgagaaa agttgcgaca gtgatccggt ggtcatcaac cgctatattt ccgttgaagc
     2941 cccccgactg gagcgtctcc gccgtctcgt ccccaggaca gtgcagcgca ggctccccac
     3001 accggagcat gtcagcagca tcatcggtgt actgacagca aaaccatccc gtaaacgtcg
     3061 taaaaaccgt acagagcctt accgtatcat tgatacattc cagcgccggt tggcaacagc
     3121 gcagacatca ctggatctgc ttccgcaata tgatacagat atcgaatccc gggcaaacga
     3181 actgtggaaa aaggctgtgc acactatcaa taacacaacc agggaagaac gccgggtatg
     3241 ttatatcaca ctgaatcgtc cggaagagga acactctggt cctgaagata taccttcagt
     3301 gaaggcgatt ctgaatactc tgctccccct ggagatgctg ttacctgtac cggatctaac
     3361 tgcatccccg ccccataaaa aaaatgtcgc tcagacacca tcaggtggaa aacaagagag
     3421 tcgtaaaaaa agattctgat aacacctgta tggctgattt taataacaac ctttacgcga
     3481 ttattaatct cctccgctca ccatagtaag cggaggattc aggatttcaa tccatcacca
     3541 gaggtacaat aaatgtgtat tagtagcccg gaaacaaact catggtctgt tatttatcgt
     3601 aaaaattccg gagaagatat caatatcact tccctgacgt ttaaaaatag tcttctggca
     3661 gcccggacac tgatggtgcc cgaaaactat atgatatgca tactcagaaa cggggagagg
     3721 gtcagacgat gggacagaga aatacttgca ggctcaaaca gatggtacaa gtgttctccc
     3781 gataatttcg aaatactggg taagctcccc ataataaata aagtcacaac actgataaaa
     3841 tcataatcta cggattttac tcagttaagc taaatcagga tgaacgcttt gattatgaat
     3901 tatacatgaa aacaaatatg ggcagcacaa aaaatggtgc cagggttccc cacgttctta
     3961 atagattcac ttctatggat attgatatga attcccagct cctgccagac atgctgatta
     4021 attttgccct tattaacatc acagacagaa agaacgaggg taccaatacc attgatggta
     4081 actggcaggc cgatgaaaga cgccgttacc gggataatgt aagaatctat ttttgagtat
     4141 gtcaacataa cctgaggcaa agtacctcag ccattgtagc cctcagattg aagaaatgat
     4201 cacacagggt gagtttacct ggcagcgttg tcatgagctg tttgcacaac agggactgat
     4261 gctacagaaa caacatcacg ggcttgttgt cgttgatgcc tttaatcatg agcaaacgtc
     4321 ggtgaaggcc agcagcattc atcctgatct gacactgggg cgtgcagagc cacaggccgg
     4381 accttttgtg agtgccccag cagatttgtt tgacagggtg caacctgaaa atcgctataa
     4441 cccggagctg gctgtcagtg acaggtacgg ggtcagcagt aaacgtgacc caatgctgcg
     4501 ccggcagcga cgtgaagcca gagctgaggc ccgtgctgac ctgcgtgccc gctatctggc
     4561 atggcgtgaa caatggcgta aaccagatct gcgttatggg gaacgttgtc gggaaattca
     4621 tcagg
//
LOCUS       DAPOXO010000181         4559 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.181, whole genome shotgun sequence.
ACCESSION   DAPOXO010000181 DAPOXO010000000
VERSION     DAPOXO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4559
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.181"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            65..394
                     /locus_tag="ROH59_004969"
                     /pseudo
     CDS             65..394
                     /locus_tag="ROH59_004969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414796.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(503..1435)
                     /gene="mmuM"
                     /locus_tag="ROH59_004970"
     CDS             complement(503..1435)
                     /gene="mmuM"
                     /locus_tag="ROH59_004970"
                     /EC_number="2.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase"
                     /protein_id="HDX4807340.1"
                     /translation="MSQNNPLRALLDKQDILLLDGAMATELEARGCNLADSLWSAKVL
                     VENPELIREVHLDYYRAGAQCAITASYQATPAGFAARGLDEAQSKALIGKSVELARKA
                     REAYLAENPQAGTLLVAGSVGPYGAYLADGSEYRGDYHCSVEAFQAFHRPRVEALLDA
                     GADLLACETLPNFSEIEALAELLTAYPRARAWFSFTLRDSEHLSDGTPLRDVVALLAG
                     YPQVVALGINCIALENTTAALQHLHGLTVLPLVVYPNSGEHYDAVSKTWHHHGEHCAQ
                     LADYLPQWQAAGARLIGGCCRTTPADIAALKARS"
     gene            complement(1422..2825)
                     /gene="mmuP"
                     /locus_tag="ROH59_004971"
     CDS             complement(1422..2825)
                     /gene="mmuP"
                     /locus_tag="ROH59_004971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414794.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methylmethionine permease"
                     /protein_id="HDX4807341.1"
                     /translation="MQTTQQNAPLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTG
                     AAGTLLAYLIGALVVWLVMQCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLT
                     WTVALGSSFTAAGFCMQYWFPQVPVWVWCVVFCAIIFGLNVISTRFFAEGEFWFSLVK
                     VVTIIAFIILGGAAIFGFIPMQDGSPAPGLSNITAEGWFPHGGLPILMTMVAVNFAFS
                     GTELIGIAAGETENPRKVIPVAIRTTIARLIIFFIGTVFVLAALIPMQQAGVEKSPFV
                     LVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNERTLPACFARVTKNG
                     VPLTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFVFRRRHL
                     QQGKALSELHYRAPWYPLVPVLGFVLCLVACVGLAFDPAQRIALWCGLPFVALCYGAY
                     FLTQPRNAKQEPEHVAE"
     gene            3033..4049
                     /locus_tag="ROH59_004972"
     CDS             3033..4049
                     /locus_tag="ROH59_004972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS5 family transposase"
                     /protein_id="HDX4807342.1"
                     /translation="MFVIWSHRTGFIMSHQLTFADSEFSSKRRQTRKEIFLSRMEQIL
                     PWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLF
                     ARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTISRWLAEAGVMMTQGTLVDATIIE
                     APSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQL
                     GNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINI
                     EYMKASIRAKVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQW
                     ERSH"
     gene            4277..>4559
                     /locus_tag="ROH59_004973"
     CDS             4277..>4559
                     /locus_tag="ROH59_004973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I deoxyribonuclease HsdR"
                     /protein_id="HDX4807343.1"
                     /translation="MPERENYQQVTLQARLVSALETLNPNVPSDTLIEVAKIVATPQT
                     PVLIKNNKLFHQYLIEGVPVEYSVMEQEQWVTKHTHVRLIDFVLWSTKTG"
BASE COUNT         1200 a         1317 c         1163 g          879 t
ORIGIN      
        1 gcatgacaaa gtcatcgggc attatctgaa cataaaacac tatcaataag ttggagtcat
       61 taccgccaac ctgttcccgg caaccttcag cgacggatac gttgatatct acggctatca
      121 tctgccgcgc ccgctgcact ttggtacaca gggtgaaggg atggtcggtg tgcgcccgga
      181 agcgatcacg ctcagcgatc gcggcgaaga gagccagcgc tgcgtgatcc gccatgtcgc
      241 ctatatgggg ccgcagtatg aagtgacggt ggaatggcac gggcaggaga tattattgca
      301 ggtcaacgct acgcgtctgc aaccggacgt cggcgagcag tattatcttg aaatccatcc
      361 gtacggcatg tttgttctgg cggatgcggc ataacgtttt gtggttttgt aggccggata
      421 aggcgcttgt gccgccatcc ggcaatgcct gatgcgctgc gcttatcagg cctacaatga
      481 acgatgtaga cccgataaac cctcagcttc gcgcttttaa cgcggcgata tccgcaggcg
      541 tggtgcgaca gcacccgcca atcaaccgtg cgccagcggc ctgccactgc ggcagataat
      601 ccgccagctg cgcgcaatgt tcaccgtgat gatgccaggt tttgctcacg gcatcgtaat
      661 gctcgcccga gttcggatac accaccagcg gcagcaccgt taaaccgtgt aaatgctgca
      721 acgcagcggt ggtgttttcc agcgcaatac agttaatgcc tagcgccacc acctgcggat
      781 aacccgccag caacgcaacc acgtcacgca gcggcgtacc gtcgctcagg tgttcgctgt
      841 cgcgcagggt aaatgagaac cacgcccgcg cacgcggata tgcggtcaac agctcggcca
      901 acgcctcaat ctcggaaaaa ttcggcaggg tttcgcaggc cagcagatcg gccccggcat
      961 ccagcaaggc ttccacgcgc gggcgatgaa acgcctgaaa tgcctcaacg ctacaatgat
     1021 aatcgccacg gtattcagag ccatccgcca gatacgcgcc gtaaggcccg acggatcccg
     1081 ccaccagaag cgttcccgcc tgcgggttct ctgccagata cgcttcacgg gctttacgcg
     1141 ccagctccac gcttttgcca atcagcgctt tcgactgcgc ttcatccaga cctcgcgcgg
     1201 cgaagcccgc cggcgtcgcc tgatagctgg cagtgatcgc gcattgcgcc cccgcccggt
     1261 agtaatcaag atgcacttcg cggataagct ccgggttttc taccagcact ttggctgacc
     1321 acaggctgtc ggctaagtta caccctcgcg cttccagctc cgtcgccatc gcgccatcca
     1381 gcagcaggat atcctgttta tcaagaagag cgcgtaacgg attattctgc gacatgttct
     1441 ggctcctgtt ttgcgtttcg gggttgagta aggaaataag caccatagca caacgcaaca
     1501 aacggtaacc cgcaccacaa cgcaattctc tgcgctggat cgaatgccag cccaacacag
     1561 gccaccaggc acagcacaaa acctaatact ggcaccagcg gataccacgg cgcgcgataa
     1621 tgtaattcac tcaatgcctt accttgttgc agatgacggc gacgaaaaac aaaatgcgag
     1681 gcgcagatac tcagccacac cgctaccacc gcaaacccgg agattgccga cagcgcaaca
     1741 aataccgtgt ccggggccac cacgctggaa aacagcgcca gcacaccacc gagcatactg
     1801 accgacagcg ccgtcagtgg cacgccgttt ttcgttactc gcgcaaaaca ggccggtagc
     1861 gtacgttcat tcgacaacga ccacagcatg cgcccggagg catataaccc ggagttcgct
     1921 gcagaaagaa tagccgtcag gatcacgaag ttaaaaatat cagcggcgta cgggatccct
     1981 actttctcaa ataccagcac aaacgggctt ttctccacgc ccgcctgctg catcgggatc
     2041 agcgctgcca gcacaaacac ggtgccgata aagaaaataa tcagtcgcgc gatggtagta
     2101 cgaatcgcta ccgggataac tttgcgcggg ttttccgttt caccggcggc aatgccgata
     2161 agctcggtac ccgaaaaagc aaagttcact gccaccatag tcatcaaaat cggtaagcca
     2221 ccgtgcggga accagccttc tgccgtgata ttactcagcc ccggcgcggg cgagccatcc
     2281 tgcatcggaa taaagccgaa aatcgccgcc ccaccgagga tgataaaggc gatgatagtg
     2341 accactttga ccagcgagaa ccagaactcc ccttcggcaa aaaagcgcgt ggagataaca
     2401 ttcagaccaa aaataatcgc gcagaacacc acgcaccaga cccataccgg cacctgtgga
     2461 aaccagtact gcatacagaa tccagcggcg gtaaagctcg aacccagcgc cacggtccag
     2521 gtcagccagt aaagccaggc cacggtatac ccggtagccg gaccaagata gcgcgcggca
     2581 taaacgtgaa acgctccggt ctccggcatc gcgaccgaca gctcgcccag acactgcata
     2641 accagccaga ccaccagcgc accaatcaga taggccagca gcgttcccgc cgctccagtg
     2701 gtggaaatga tgtacccggt attgaagaat aatcctgtgc caatcacgcc gcccaaggaa
     2761 agcataatca ggtgacgcgt tttcattgtg cgcttcagtg gcgcattttg ttgtgttgtt
     2821 tgcatataac cttctaaacg tatggacatc taaacatcca aagaaggttt gttataccgc
     2881 gtttgttaac agaatgcaaa gtcaaccctg caccagacgc agatgcccgc gccgggcgct
     2941 taatagcggg tggggattaa taatcagata caaaaagggc cgccagctca taacgcctcc
     3001 ggaaggtgcg aacaagtccc tgatatgaga tcatgtttgt catctggagc catagaacag
     3061 ggttcatcat gagtcatcaa cttaccttcg ccgacagtga attcagcagt aagcgccgtc
     3121 agaccagaaa agagattttc ttgtcccgca tggagcagat tctgccatgg caaaacatgg
     3181 tggaagtcat cgagccgttt taccccaagg ctggtaatgg ccggcgacct tatccgctgg
     3241 aaaccatgct acgcattcac tgcatgcagc attggtacaa cctgagcgat ggcgcgatgg
     3301 aagatgctct gtacgaaatc gcctccatgc gtctgtttgc ccggttatcc ctggatagcg
     3361 ccttgccgga ccgcaccacc atcatgaatt tccgccacct gctggagcag catcaactgg
     3421 cccgccaatt gttcaagacc atcagtcgct ggctggccga agcaggcgtc atgatgactc
     3481 aaggcacctt ggtcgatgcc accatcattg aggcacccag ctcgaccaag aacaaagagc
     3541 agcaacgcga tccggagatg catcagacca agaaaggcaa tcagtggcac tttggcatga
     3601 aggcccacat tggtgtcgat gccaagagtg gcctgaccca cagcctggtc accaccgcgg
     3661 ccaacgagca tgacctcaat cagctgggta atctgctgca tggagaggag caatttgtct
     3721 cagccgatgc cggctaccaa ggggcgccac agcgcgagga gctggccgag gtggatgtgg
     3781 actggctgat cgccgagcgc cccggcaagg taagaacctt gaaacagcat ccacgcaaga
     3841 acaaaacggc catcaacatc gaatacatga aagccagcat ccgggccaag gtggagcacc
     3901 catttcgcat catcaagcga cagttcggct tcgtgaaagc cagatacaag gggttgctga
     3961 aaaacgataa ccaactggcg atgttattca cgctggccaa cctgtttcgg gcggaccaaa
     4021 tgatacgtca gtgggagaga tctcactaaa aactggggat aacgccttaa atggcgaaga
     4081 aacggtctaa ataggctgat tcaaggcatt tacgggagaa aaaatcggct caaacatgaa
     4141 gaaatgaaat gactgagtca gccgagaaga atttccccgc ttattcgcac cttccctaga
     4201 acaacaatgc ctcgattggt ttaaagagct aggttaccaa taccaaaatg gctatgacat
     4261 cgcaccagat ggtgatatgc ctgaacgtga aaactatcag caagtcacgc tacaggcgcg
     4321 tttagtctct gccttggaaa ccttaaaccc aaatgtgccc agtgacacct taatcgaagt
     4381 agcgaaaatc gttgccacac cgcaaacgcc tgtactgatt aaaaacaaca aactctttca
     4441 ccaatattta atcgaaggtg tgcctgttga atactcggta atggagcaag aacaatgggt
     4501 gaccaagcat actcatgttc gattaattga ttttgtgttg tggtcaacta aaactggcc
//
LOCUS       DAPOXO010000182         4548 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.182, whole genome shotgun sequence.
ACCESSION   DAPOXO010000182 DAPOXO010000000
VERSION     DAPOXO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4548
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.182"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..153
                     /locus_tag="ROH59_004974"
     CDS             <1..153
                     /locus_tag="ROH59_004974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX4807344.1"
                     /translation="LTSLVINRQLWLYHDSGDAGLTQLYRMRDAQLWRHIEFHPECNA
                     IYAALD"
     gene            200..622
                     /locus_tag="ROH59_004975"
     CDS             200..622
                     /locus_tag="ROH59_004975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDX4807345.1"
                     /translation="MYCTVKEIIREVLDTDVPDSECVFAVVLTRGDVRHIAQDWSLTD
                     DELETVMQRLDDAFEYGADVSVVHGVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGETMS"
     gene            619..810
                     /locus_tag="ROH59_004976"
     CDS             619..810
                     /locus_tag="ROH59_004976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807346.1"
                     /translation="MNISTETREILRNYRAVINARRREMGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(780..1260)
                     /locus_tag="ROH59_004977"
                     /pseudo
     CDS             complement(780..1260)
                     /locus_tag="ROH59_004977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001358895.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1773..2003
                     /locus_tag="ROH59_004978"
     CDS             1773..2003
                     /locus_tag="ROH59_004978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807347.1"
                     /translation="MTISIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            2055..3416
                     /locus_tag="ROH59_004979"
     CDS             2055..3416
                     /locus_tag="ROH59_004979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HDX4807348.1"
                     /translation="MTLAAITMTAPEAASPVQMYRATYSPDDNKLRLYAASRLDPETY
                     KKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDHISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLDESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFREMTKAQWAALPRDCKAVRSVEEAEDHGAYRYRRTMDNNFRLVNVYITDMKITEI
                     PQK"
     gene            3463..4026
                     /locus_tag="ROH59_004980"
     CDS             3463..4026
                     /locus_tag="ROH59_004980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDX4807349.1"
                     /translation="MHSQLRERIRLMRARLDNAAPVAEIRAESQLFVSPAPICDRLVT
                     LAEISNRDHILEPSAGTGAILRAIRDTAPEAMCDAVEINSGLVRYLRENFNGVRVQCG
                     DFMEWQSVQYYSRIIMNPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLP
                     FSDVREELPRGTFAYTDVPTMIIRLRA"
     gene            complement(4112..4548)
                     /locus_tag="ROH59_004981"
                     /pseudo
     CDS             complement(4112..4548)
                     /locus_tag="ROH59_004981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052655.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          979 a         1266 c         1366 g          937 t
ORIGIN      
        1 ctgacctccc ttgtgattaa ccgccagttg tggctgtacc acgacagcgg ggatgcagga
       61 ctgacccagc tttaccggat gcgcgatgcg cagttgtggc gtcacatcga atttcacccc
      121 gaatgcaacg cgatttacgc ggctctggac tgattaacgg acggggcggc aatgccgccc
      181 ctgtaaagga gacgagaaca tgtactgtac tgttaaagaa attatccgcg aagtgctgga
      241 tacagacgtg ccggacagtg aatgcgtttt tgccgtagtg ctgacccgtg gggatgtgcg
      301 tcacatagcc caggactgga gtctgacaga cgatgagctg gaaaccgtca tgcagcggct
      361 ggacgatgcc tttgaatatg gtgcggatgt cagcgttgtt cacggcgttg ttcgtgaact
      421 gatggaagaa aagcgcgcca gccgtcaggt gacagtcccg gcggtgatgc tggaaaaagt
      481 gatggcgctg gcaggcagtg aaatgaagcg cctgtatgcc gtcgggagtg agaacggggg
      541 cgacggtgac gcattcgtca gggaggaacg cgaagcaatg gacgttgtgt tacaggcgct
      601 ggacggggag acgatgtcat gaatatcagc acagaaaccc gcgaaattct gcgtaattac
      661 agggccgtga ttaatgcgcg gcgtcgtgaa atggggcaga aaccgctcac caccgcgcag
      721 attgttgatg aaatctgcga ttttgtggcg aatcagcagg cggttttcct gggcggtcac
      781 tacatcttac agggtagcag aaacaggtga tacaggggca ggcggtggag gccgcctgtc
      841 agcccgcgcg aacccccctg gcaggctggc gcctgccgga agggtaacgg gccacgctgg
      901 cgcgtcgccc gttacccttc ccgtttgtga tgtgtccgga atgttttttc ctgatgttat
      961 gtttctgtgg ttactgttct tcttcttcct cttctttccg ttcctctcct gtttatggct
     1021 ttcccgggcg tcccccaggc ggggcgggct gtcgtgaacg gagccagcgg agctgtctcc
     1081 gccctggcgg gcttccatcc ctgacgcaaa acccccggct tgcagcgacc gttccggtcg
     1141 cgccgcccct gtcgcgccgt ggcctgcgct cctggcatcc cggcaaaacg acgccgggat
     1201 gtaaggcgca acgccgtttc gcgcacgcgc tctccgtcgt tgcggcgggt ccctgctcat
     1261 tgcctgccgg gtgccacaca cccgtatgag tccctgtcgc cgggggcata gacagccaca
     1321 acctgccgca ctgactgtcc agggtaaatg aacagcccac aaaatttttt acccaaaacc
     1381 cggtaaaaaa ttttgcgttc tgcccaggac aggtgcgtca ggccgtggca gtgatgcccc
     1441 ttgcggcgaa ggttctcaaa cgggtgaagt tcataccaca gggaatacag cagcaggttc
     1501 ccgcgaaacg tcaaaaccgc ggctcccaaa actcaacggg tgatgttctt taaaaatcag
     1561 gatttatttc aggctccggc aatacgcatt tatgtgttct gtcagtcatc cggctggcag
     1621 gtaatgagaa cgcaggaaca gaaggaggaa aacaccggaa aacgtcagat gcagatatga
     1681 aaaaagcagg tcagggacct gcttaatcca tgccgcagag actgcacgaa cagtttttgc
     1741 ggctccagtc aatcgtcata agaggctaaa ttatgacaat aagtattgtt tcaccttccg
     1801 cagcggctgt aaagccccgc cgtcatcccc gtttcagacg cgaagacatc cccgcgccgg
     1861 aaattgaccc cgtgctgaaa gccttcgggc gacacatagc ccggagtttt caccgggggc
     1921 gtggtgtaca catccccgcc atgaaaaaca cggctttcgg gcaggtgctc cgcacactcg
     1981 aactgaaacg cgcttttaac tgatgaggtg agccgccccg cgaggggcgg caacagacgg
     2041 aaggagaaca ttttatgaca ttagcagcaa tcaccatgac cgccccggaa gccgccagcc
     2101 ctgtgcagat gtaccgcgcg acctactcac cggatgacaa caaactgcgc ctgtatgccg
     2161 cgtcacgtct tgacccggag acgtataaaa aagtgcatga tgccggtttc cgctgggcac
     2221 ccaaacaggc gctgtttgtc gcgccagcct ggacaccggg ccgggaagac gtgctcctct
     2281 cacttgccgg agagattgag gatgaagaca gcacgctcgc tgaacgtcag gaagcacggg
     2341 cggagcggtt taccggatac agcggaaagc gggccagtga atccgcacag gcacttgatg
     2401 aagtggaaag actggccgcg atgatcccgc ccggtcagcc cattcttgtg gggcatcaca
     2461 gcgaacgccg cgcccgtcgt gatgcgcagc gtattgaaaa cggcatgaaa cgtgccgtga
     2521 tgctctttga acgtgcggaa tactgggaag aacgggcgcg gtcggcactg cttcacgcga
     2581 agtataaaga acgcccggac gttcgctggc gtcgtatcaa aaaaatcgaa gctgatttgc
     2641 gcaaggctga aaagaccatc gcacagtcgc agaaatatct gacgatgtgg cgggctgaat
     2701 cgctggatct gaatatggca aaactcatca gcagtcatga ccatatcagc gcctgtttcc
     2761 cgctggatac gtatccgcgc ccggcagaaa aaagccagta tgaagggagc cggtcgttat
     2821 ggtcggccct ggatgatgac atcatcacca cggagcaggc ccgcgaaatt gcgatccgct
     2881 gtcatgaacg gcagattcag catcagcaac gctgggttaa ccactatcag aaccgcctga
     2941 tctatgagcg tgccatgctg gacgaaagcg gcggcgtggt tacccggaca caggattttg
     3001 agccgggcgg acaggttttc agccggggcg agtggctgac tatcatccgc gtgaacaaaa
     3061 gcaacggggc ggtgagttca gtcacaacgc caaattacag ttttctcggg tacagcggca
     3121 cgatgaaagt gacgcccgat cgcatcacgg actacaaagc accatcggca gaagaggctg
     3181 ccgtcgccag tcaggccgcg aagcgtccgc cggtagtcaa ctatccgggg gaaggtttcc
     3241 gggaaatgac aaaggcgcag tgggccgccc tgccccggga ctgtaaggcc gtgcgcagtg
     3301 tggaagaagc agaagaccac ggggcatacc gctaccgccg cacaatggac aataatttcc
     3361 gtctggtgaa tgtgtatatc accgacatga aaatcacgga aatcccacag aaataaggta
     3421 tatccccccg ggaaatcccc gggggatgac ggagataatg acatgcacag tcagttaaga
     3481 gaacgtatcc ggctgatgcg cgcaaggctg gataacgccg cgccggttgc tgaaatccgg
     3541 gctgaatctc agctttttgt gagtcctgcc ccgatctgtg atcgcctggt gacgctggcg
     3601 gaaatcagca accgtgatca cattctggaa ccctctgccg gcaccggggc catactgcgg
     3661 gcgattcggg ataccgcgcc ggaggccatg tgtgatgcgg tggagattaa cagcgggctg
     3721 gtccggtatc tgcgggaaaa ttttaacggt gtcagggtac agtgtggcga cttcatggaa
     3781 tggcagtcgg tgcagtatta cagccggatc attatgaatc cgccgttcag tcacgggcag
     3841 gatatccggc atatcctgcg ggctttttcc ctgttgcgtc cggggggcgt tctggttgcc
     3901 gtctgtctca acgggccacg ccagcaggag aagctgttac cgttttctga cgtccgcgag
     3961 gagctgccgc gcggcacgtt tgcttatacc gatgtcccga cgatgattat tcgtttgcgt
     4021 gcctgatgac acagggctgg cgggaggata aatgcccgtc tgtccgcgcc gggaaaaaac
     4081 cgcgcgtcgg tggcgctgaa aggggccgcg ctcacgcgcc gcccctttca ttacgcggac
     4141 gttctgatgg gggcttctgt cttttcagac ctgtcatttg tctgttactg atgatgttgt
     4201 tgttcctgct actgctactg ctactgctac tgttcttctt ttttctactg ctctgattac
     4261 tgtctgtttt gttgttctcc tgcttatgcc ttttccgggc gtccccctgg cggggcgggc
     4321 tgtcgtgaac ggagccagcg gagctgtctc cgccctggcg ggcttccatc cctgacgcaa
     4381 aacccccggc ttgcagcgac cgttccggtc gcgccgcctc tgtcgcgccg cctctgtcgc
     4441 gccgcctctg tcgcgccgtg gcctgagctc ctggcatccc ggcaaaaggc cgccgggatg
     4501 taaggcgcaa cgccgtttcg caaaccgcgc ttcacgtcgt tgcggcgg
//
LOCUS       DAPOXO010000183         4466 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.183, whole genome shotgun sequence.
ACCESSION   DAPOXO010000183 DAPOXO010000000
VERSION     DAPOXO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4466
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.183"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..633)
                     /locus_tag="ROH59_004982"
     CDS             complement(<1..633)
                     /locus_tag="ROH59_004982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807350.1"
                     /translation="MNEQIKQDIDLIEILFYLKKKIRVILFIIAICMAMVLLFLYINK
                     DNIKVSYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFQTSPDVKNREIK
                     LEWSGDKRDLPTAEAEISRVQASIIKWYTSEYHNGRQVLDEIQTPSAINSELYTKMIY
                     LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKK"
     gene            complement(817..2010)
                     /locus_tag="ROH59_004983"
     CDS             complement(817..2010)
                     /locus_tag="ROH59_004983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX4807351.1"
                     /translation="MTKATVNTGTFASQNGTLIVDASSENTLDISGKASGDLSVYSAG
                     SLDLINEQTAFISTGKDSTLKATGTTEGGLYQYDLTQGADGNFYFVKNTHKASNASSV
                     IQAMAAAPANVANLQADTLSARQDAVRLSENDKGGVWIQYFGGKQKHTTAGNASYDLD
                     VNGVMLGGDTRFMTEDGSWLAGVAMSSAKGDMTTMQSKGDTEGYSFHAYLSRQYNNGI
                     FIDTAAQFGHYSNTADVRLMNGGGTIKADFNTNGFGAMVKGGYTWKDGNGLFIQPYAK
                     LSALTLEGVDYQLNGVDVHSDSYNSVLGEAGTRVGYDFAVGNATVKPYLNLAALNEFS
                     DGNKVRLGDESVNASIDGAAFRVGAGVQADITKNMGAYASLDYTKGDDIENPLQGVVG
                     INVTW"
     gene            complement(2032..2703)
                     /gene="hyxB"
                     /locus_tag="ROH59_004984"
                     /pseudo
     CDS             complement(2032..2703)
                     /gene="hyxB"
                     /locus_tag="ROH59_004984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane autotransporter HyxB"
     gene            complement(2684..3391)
                     /locus_tag="ROH59_004985"
     CDS             complement(2684..3391)
                     /locus_tag="ROH59_004985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4807352.1"
                     /translation="MKKPLVIISACQFTRLALESLIPTDRYIVRVYSNVTTEVEFVLK
                     TSCGYLLADIPSLPSGELVLLACLARLRSDAGQWQVCLTGDSDWFDNAPAASLYNGFP
                     RIGTMLTASRYQNQIIRWLLRPLPGDMSDFWLLTARELSVLKILMQGMSFSEIARYEQ
                     RSSKTLHAIATRALMKLGLRTLSDFRLLYTGCGDSRVKRNIRLHAKYIGQHSAHRLTQ
                     YVQNMVSGILYQLCCKK"
     gene            complement(3721..4284)
                     /gene="ipbA"
                     /locus_tag="ROH59_004986"
                     /gene_synonym="fimX"
     CDS             complement(3721..4284)
                     /gene="ipbA"
                     /locus_tag="ROH59_004986"
                     /gene_synonym="fimX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060710320.1"
                     /note="IpbA is also known as HbiF and FimX; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase IpbA"
                     /protein_id="HDX4807353.1"
                     /translation="MTRKYLTQDEVYRLMDAAQSMSFPERNRCLIMMAFIHGFRASEL
                     LDLRLSDIDASGKQLNIRRIKNGFSTTHPLLPDEYNLIKLWLKQRKLIENGVEGDWLF
                     LSRKRRPISRQHFFSIIREAGKRAGLAVKAHPHMLRHACGFALADNGVDTRLLQDYLG
                     HRNIQHTVRYTASNAARFKGVWKKKPR"
BASE COUNT         1226 a         1008 c          933 g         1299 t
ORIGIN      
        1 ttttttgaca aggcaaaaca ttacagaaat cacaatactt agaaaaaatc ccagagccag
       61 gcaaatggca gcagggtatt tattttttat ttctggtgag cttatagtga cacagccatc
      121 accgttcgga tacagtgacc agttcctggt cagatatatc atttttgtat aaagctcact
      181 gttaattgct gaaggcgttt gtatctcatc gagaacttgc ctgccattat ggtattctga
      241 cgtataccat ttaatgatag acgcctgcac gcgagatatt tccgcttcag cagttggtaa
      301 atctctctta tctcctgacc attccagctt tatttctctg ttcttgacat ctgggctggt
      361 ctgaaaaaat gtagtaattc gctgaataac atcttcagtc attgtggtct gacaggcaaa
      421 gttattattg ctatcacagc taacaagtat gcctggtgtt gtctgattta tttttaggct
      481 gtaactcact tttatattat ctttattgat atacagaaac aacagcacca ttgccataca
      541 gatagctata ataaaaagga taacacgaat ctttttcttc agataaaata aaatctcaat
      601 cagatcgata tcctgtttga tttgttcatt cataatatat ccagaaaatg aaatctgtcg
      661 cagataaggt tgtattaata gtctgtatca ggaatgttca gggtaaatat cagcaaaaag
      721 ccagcatcat gagtactgga tatttatagc ctgcaggcag catactgctg cctgcagggg
      781 gtataacagt cgacagggga accgactgct ttattcttac caggtcacat tgataccaac
      841 tacaccctgt agcgggttct caatgtcgtc acctttggtg tagtcaaggc ttgcatatgc
      901 tcccatgttt ttggtgatat cagcctgtac acctgcaccc acgcggaatg ctgcaccgtc
      961 aatgctggca ttgacagact catcacccag acggactttg ttgccatcag agaattcgtt
     1021 cagtgcggcc agattcagat aaggtttaac ggtcgcgttg cccacagcga agtcataacc
     1081 cacgcgcgta ccggcctcac ccagcacaga gttatagctg tcagaatgaa cgtccacgcc
     1141 gttgagttga taatccacac cttccagagt cagagcagac agtttggcat atggctgaat
     1201 aaacaggcca ttaccgtctt tccatgtgta accgccttta accatcgcac caaaaccatt
     1261 ggtgttaaag tcagctttga tggtaccgcc accattcatc aggcgaacat ctgccgtgtt
     1321 gctgtagtga ccaaactgtg cagcagtatc aatgaagata ccgttgttat actggcggct
     1381 caggtaagcg tggaagctgt aaccttcagt gtcacctttg ctctgcatgg tagtcatgtc
     1441 acctttcgca gaagacatcg ccacaccggc cagccagcta ccatcttcag tcatgaagcg
     1501 ggtatcacca cccagcatta caccatttac atccaggtca taggatgcat ttcccgcggt
     1561 ggtatgtttc tgtttaccgc caaagtactg aatccatacg ccacccttgt cattttcgct
     1621 cagacggaca gcatcctgac gggcggagag cgtgtcagcc tgcagattag cgacgttagc
     1681 cggagcagct gccattgcct gaatcacgga gctggcgttg gatgctttat gcgtgttttt
     1741 tacgaaataa aagttaccat cagctccctg tgtcaggtca tattgataca gaccaccttc
     1801 cgttgtgcct gtggctttta gagtgctgtc tttgccggta gaaataaatg ccgtttgttc
     1861 attgataaga tccaatgaac ccgcactgta aacactcaag tcaccgctcg cttttccgct
     1921 gatatccaga gtgttttcag aagaggcatc aacaatcaga gtgccgtttt gagaagcaaa
     1981 cgtgccagta ttgactgtag ccttcgtgat attaaccgta ctgtctttta ctgccagagc
     2041 atcaacagtt gaggaacccg taacattcca gacagacccg ttttgcagag atacactggc
     2101 atctcctgcc cctgaaactt tgcctttcca gactgaacta tcggaaagat ttatatccag
     2161 atcactaccc gctttatcgc cgctattgag cgtataagca ttaccttccc agtaagagcg
     2221 ggcaacgttc atatttacat ttgttgtggt accggctgaa ttctcgcttt cagaaagggc
     2281 caggacatca gagtagatgg ttgaatcagc aacagacaaa tttaaatttt gcgttgctga
     2341 acctgcgcct tgtgccgaag cagaggcata aattgtttgt ttattattag ccgccccaat
     2401 tattgagcca tccttaatat tcaggttgac tgtatgaatt cccttattct ccttggcaat
     2461 aactattgtt tcaatcccac cattaataat atttgagtca gcaagggtga tgttgtcggt
     2521 tgcatcaccg tcaaaaccct gcaacaaatt acccttttga gcaaaaattg ccgtagagcc
     2581 gttgctggaa ctcttattac cttgagcatt tatggttgtg ccattgagcg ttaaattatt
     2641 tcccgtggtc gcttccagag atatacctgt cgcactactt ttttcatttt ttgcaacaaa
     2701 gttgataaag gattccggat accatgttct gcacatactg agtgagtcga tgagcggaat
     2761 gttgtccgat atattttgca tgtagccgta tattccgttt cactctgctg tcaccgcatc
     2821 ccgtatagag cagcctgaaa tcgctcagtg ttctcagtcc aagtttcatt aaagcccgtg
     2881 tggcaatcgc atgcagggtc tttgaactgc gttgttcata acgggcaatc tcactgaaac
     2941 tcatgccctg catcagaatc ttaagcacgc tcaactcccg tgcagtcagg agccagaaat
     3001 cgctcatatc gccgggcaaa ggacgcagta accagcggat aatttgattc tgataacgac
     3061 tcgctgtcag catggtgccg atgcgtggga agccgttata cagacttgca gcaggagcat
     3121 tatcgaacca gtcggagtca ccggtcaggc agacctgcca ttgcccggca tcactccgca
     3181 aacgggcgag acaagccaga agaaccaact cccccgaagg aagcgaaggg atatcagcta
     3241 acaggtagcc acaggaggtc tttaaaacga attcaacctc tgtagtgacg ttgctgtaca
     3301 cccgcacgat atacctgtcc gttgggatga gagactccag tgccagcctg gtgaactgac
     3361 aggcactgat aataaccaga ggcttcttca ttcagactcg tccacgccat tgctacaaaa
     3421 cctgacattt tgattcaaaa tgtcaggttt ggtttaatag cctgaatatt taattttctt
     3481 ggaatataaa tctaatttgt ttgattttta ttgtttttaa ttttgtgtta tttaacgata
     3541 tgggcgaaag ttaatcactg gtatgacctt tgtgattaat catttcaaat catagggtta
     3601 ttttacttta gctagaaata tcaacatgtt atgtgtttta tttaattgaa tgggctgttt
     3661 ttttatggaa gaattgagga aaacgtagga atctgacatt ttgaatcaga aggtactgtt
     3721 ttaacgaggc ttttttttcc acaccccttt aaaacgagca gcattactgg ctgtgtatct
     3781 gacagtatgc tgaatatttc gatgacccag ataatcctga agtagtcggg tatcgacacc
     3841 attgtcagcc agagcaaaac cacaggcatg acgtaacata tgaggatgtg cttttacagc
     3901 taatcctgca cgttttccag cctcacgaat gatagaaaaa aaatgttgtc tgctgatagg
     3961 gcggcgtttc cgggagagaa aaagccagtc tccttcaact ccgttttcaa ttaacttcct
     4021 ctgcttaagc cacaacttga tcaaattata ttcatcagga agaagaggat gtgttgtcga
     4081 gaaaccattt ttaatacgcc gaatattaag ttgttttcca gatgcatcaa tatcggataa
     4141 acgtaaatca agaagttcac tggccctaaa accgtgaatg aaagccatca taattagaca
     4201 gcgatttctt tcaggaaagg acatgctctg ggctgcatcc atcagcctgt agacttcatc
     4261 ctgtgtgaga tattttctcg tcatacgcca ccgtgtacag ttgtaaaaaa aagagaggca
     4321 cacccagata agtatgcctg caatcagaac gttatcgatg taatctcatt atctcattaa
     4381 taagattttt tgaatagtag ttctacgcaa cagattaaat atgaactatt tattgtgcag
     4441 cttttctaca agtcattttt aatgcg
//
LOCUS       DAPOXO010000184         4340 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.184, whole genome shotgun sequence.
ACCESSION   DAPOXO010000184 DAPOXO010000000
VERSION     DAPOXO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4340
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.184"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            124..1149
                     /locus_tag="ROH59_004987"
     CDS             124..1149
                     /locus_tag="ROH59_004987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX4807354.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDVCRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPTEWIVL
                     PEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            1217..2398
                     /locus_tag="ROH59_004988"
     CDS             1217..2398
                     /locus_tag="ROH59_004988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDX4807355.1"
                     /translation="MPHRRSTVKGSLSFANPTVRAWLFQILAVVAAVSIVGWLFHNTV
                     TNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRIFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWP
                     FAAVLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSIYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            2408..3511
                     /locus_tag="ROH59_004989"
     CDS             2408..3511
                     /locus_tag="ROH59_004989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDX4807356.1"
                     /translation="MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLVVWWLMYGGFLGLDRVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH"
     gene            3519..4277
                     /locus_tag="ROH59_004990"
     CDS             3519..4277
                     /locus_tag="ROH59_004990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDX4807357.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEALAMHYLERVRIAEHAQKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFAHPKSERTRAFLSQVIH"
BASE COUNT          996 a         1014 c         1137 g         1193 t
ORIGIN      
        1 ttgcgacgcg aaatcgtgcg caaaagctgg cactactttt gcttataaga ggatggccac
       61 agacaggtaa aagacgtttc ccaaacgtcc tataacgata attttcgcct cacaggaagc
      121 attatgaaaa agatgatgat agccacactg gctgccgcca gcgtgctgct tgccgttgca
      181 aatcaggcgc atgctggcgc gacgcttgat gccgttcaga aaaaaggttt tgtgcaatgc
      241 gggatcagtg atggattacc tgggttctct tatgccgatg ctgacggtaa gttttcaggt
      301 attgatgtag atgtttgtcg tggtgttgcc gctgctgtat tcggtgacga tacgaaagtg
      361 aaatataccc cgctcactgc aaaagaacgc ttcaccgctt tacagtcagg ggaggtggat
      421 ttgctctccc gtaatacgac ctggacttca tctcgcgatg ccgggatggg aatggcattt
      481 actggcgtca cttattacga cggcattggc ttcctgacgc acgataaagc ggggctaaaa
      541 agcgcgaaag aactggatgg cgctaccgtc tgtattcagg cggggactga taccgaactc
      601 aacgtcgccg attacttcaa ggcaaataat atgaagtaca cgccagtaac cttcgatcgc
      661 tcagacgaat cagcgaaggc tctggaatct ggccgctgtg atactctggc ctcggatcaa
      721 tcacaactgt atgccctacg catcaaatta agcaacccaa ctgaatggat tgtcttaccg
      781 gaagttatct ctaaagaacc acttgggccg gtagttcgtc gtggcgatga tgaatggttc
      841 tcgattgtac gctggacgct tttcgccatg ctgaatgctg aagagatggg catcaattcc
      901 cagaatgtcg atgaaaaagc ggctaatcca gcaacgcctg atatggcaca tctgctgggt
      961 aaagaaggcg attacggcaa ggatctgaag ctggataata aatgggccta taacatcatc
     1021 aaacaggtgg gtaactactc ggaaattttc gagcgtaacg taggttcaga aagcccgctg
     1081 aaaattaaac gtgggcaaaa taatctctgg aataacggcg gtattcagta cgcgccgccc
     1141 gtgcgttaag tcggtgtgag gtaacgagcg ttgctacggc ggcgctcttt tcagcgttat
     1201 ggttttcgag gtttctatgc cccatcgccg ctcaaccgtt aaaggctcac tctcttttgc
     1261 caaccctacg gttcgcgcct ggttattcca gatccttgcc gttgttgctg ctgtcagcat
     1321 tgttggttgg ttatttcaca acactgtaac gaatctcagt aatcgtggca taacatcagg
     1381 atttgctttt cttgaccgcg gggccggttt tggcatcgtt cagcatttga ttgattatca
     1441 gcaaggcgac acttacggac gcatttttat tgtcggccta ctcaatacgc tactggtttc
     1501 tgcattgtgt attgtgttcg cttctgtttt gggcttcttt atcggtctgg cgagactttc
     1561 ggataactgg ctgctacgaa agctttccac aatttatatt gagatcttcc gtaatattcc
     1621 cccgctgctg caaatcttct tctggtactt tgccgtgttg cgcaatttgc ccggaccacg
     1681 acaggcagtg agcgcgtttg acctggcctt tttgagcaat cgtgggcttt atattccgtc
     1741 gccgcagctg ggagacggat ttattgcgtt tatcctggct gttgttatgg ctatagtcct
     1801 ttctgttggg ctattccgct ttaataaaac ataccagata aagaccggac aactgcgccg
     1861 cacctggcca ttcgccgctg tgttgatcat tggtttgcct ttactggcgc aatggctttt
     1921 tggcgcagca ctacactggg atgtcccagc ccttcgaggc tttaatttcc gcggcgggat
     1981 ggttttaatt cctgaactgg cagccttaac gctagcactt tcgatttata cctctgcatt
     2041 tatcgccgag attatccgcg cagggatcca ggcagtgcct tatggtcaac atgaagcggc
     2101 tcgatcactg ggattaccca acccggttac gctacgccag gtcattattc cccaggcatt
     2161 gcgggtgatt attccaccgt taaccagcca gtatctcaac atcgtcaaga actcctctct
     2221 tgccgccgct attggctatc ccgatatggt ttcgctgttt gctggcaccg tgctgaacca
     2281 aacggggcaa gccatcgaga cgatagccat gaccatgtcg gtctatctga ttatcagcct
     2341 gactatctcg ctgctgatga atatctataa ccgccgcatc gcgatcgttg aacgctaagg
     2401 agtcatgatg acaaaagtat tgctgtctca tcccccgcgc ccggcgagcc ataactcaag
     2461 ccgcgcgatg gtgtgggtgc gaaaaaatct gttctccagc tggagcaata gcctgctgac
     2521 tattggctgc atatggttga tgtgggaact gatcccaccg ttgctgaact gggcattttt
     2581 gcaggctaac tgggttggct caacgcgtgc cgactgcaca aaagccggtg cctgttgggt
     2641 cttcatccac gaacgatttg gtcagtttat gtatggactt tacccacacg accaacgctg
     2701 gcgaattaac ctggcattac tgattggcct tgtgtctatc gcaccaatgt tctggaaaat
     2761 acttccgcat cgcggtcgct atattgcggt ctgggcggtg atttacccac tggttgtctg
     2821 gtggctgatg tatggtgggt ttcttggtct tgatcgggtt gaaacccggc aatggggcgg
     2881 gttgacgcta actttaatta ttgcatcagt tgggattgcg ggggcgctac cgtgggggat
     2941 cttactggcg ttaggtcgcc gctcccatat gccgattgtg cgtatcttat cggtcatttt
     3001 tatcgagttc tggcgcggcg taccgctgat taccgtattg tttatgtctt cggtcatgct
     3061 gccgttgttt atggcagaag gcaccagtat cgataaactg atccgcgcgc tggttggcgt
     3121 gatcctgttt cagtcagcat atgttgcgga agtcgtgcga ggcggattac aggcgctgcc
     3181 taaagggcaa tatgaagcgg cagagtcgct ggcattgggt tattggaaaa ctcaggggct
     3241 tgttattctg ccccaggcgt tgaagctggt aattcctggg ctggtaaata ccatcatcgc
     3301 actcttcaaa gataccagtc tggtgatcat catcgggttg ttcgatcttt tcagtagcgt
     3361 tcagcaggca accgttgatc ccgcgtggtt gggtatgtcg acggaagggt atgttttcgc
     3421 cgcgctgatc tactggatct tctgtttcag catgtcacgt tatagccaac atctggaaaa
     3481 acgttttaac accgggcgta caccgcattg aggacactat gagccaaatt ttactgcaac
     3541 ctgctaacgc gatgattacg ctggaaaacg tcaataaatg gtatggacaa ttccatgttt
     3601 tgaaaaatat aaatttaacc gtgcaaccgg gcgaacggat cgttctatgt ggcccttcag
     3661 gttccggtaa atcaacaacc attcgttgta ttaatcatct ggaagaacat caacagggac
     3721 ggatcgtggt agatggcatc gaacttaatg aagatatccg caatattgag cgcgtcaggc
     3781 aggaagtggg aatggtcttt cagcatttca atctcttccc tcatctgacc gtgttacaga
     3841 actgtaccct ggcaccgatt tgggtacgca agatgccaaa gaaagaggct gaagctctgg
     3901 cgatgcatta ccttgagcgg gtgagaattg ccgaacatgc ccagaagttt cccggacaga
     3961 tttctggtgg tcagcagcaa cgtgttgcca tagcacgttc gctgtgtatg aagccgaaaa
     4021 ttatgttgtt tgatgagcca acgtcggcgc tcgatcctga gatggtgaaa gaggtgctgg
     4081 atacgatgat tgggctggcg cagtcgggta tgacaatgtt gtgtgtaaca catgagatgg
     4141 ggtttgcacg aaccgtcgct gaccgggtga tttttatgga tcgtggggaa atagtggagc
     4201 aagctgcacc tgatgaattt tttgcgcatc ctaaatcaga gcgtacgagg gcatttttat
     4261 cgcaggtaat ccattaattg aatattagtt cgaaaagcaa aaaggccatc ctttcggatg
     4321 gcctttcgcc tgatttgatg
//
LOCUS       DAPOXO010000185         4278 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.185, whole genome shotgun sequence.
ACCESSION   DAPOXO010000185 DAPOXO010000000
VERSION     DAPOXO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4278
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.185"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..299)
                     /gene="tuf"
                     /locus_tag="ROH59_004991"
     CDS             complement(<1..299)
                     /gene="tuf"
                     /locus_tag="ROH59_004991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDX4807358.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQM"
     gene            complement(414..489)
                     /locus_tag="ROH59_004992"
     tRNA            complement(414..489)
                     /locus_tag="ROH59_004992"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(454..456),aa:Thr,seq:ggt)
     gene            complement(496..570)
                     /locus_tag="ROH59_004993"
     tRNA            complement(496..570)
                     /locus_tag="ROH59_004993"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(535..537),aa:Gly,seq:tcc)
     gene            complement(687..771)
                     /locus_tag="ROH59_004994"
     tRNA            complement(687..771)
                     /locus_tag="ROH59_004994"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(735..737),aa:Tyr,seq:gta)
     gene            complement(780..855)
                     /locus_tag="ROH59_004995"
     tRNA            complement(780..855)
                     /locus_tag="ROH59_004995"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(820..822),aa:Thr,seq:tgt)
     gene            1217..2167
                     /gene="coaA"
                     /locus_tag="ROH59_004996"
                     /gene_synonym="panK"
     CDS             1217..2167
                     /gene="coaA"
                     /locus_tag="ROH59_004996"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDX4807359.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2196..3161)
                     /gene="birA"
                     /locus_tag="ROH59_004997"
     CDS             complement(2196..3161)
                     /gene="birA"
                     /locus_tag="ROH59_004997"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HDX4807360.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGESLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAEQILGQLDGGSVTVLPVIDSTNQYLLDRIGELK
                     SGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNSLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(3158..4186)
                     /gene="murB"
                     /locus_tag="ROH59_004998"
     CDS             complement(3158..4186)
                     /gene="murB"
                     /locus_tag="ROH59_004998"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDX4807361.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAEGQPVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRD
                     SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKVLLAQFPTAPNYPQADGSVKLAAGWLIDQCQLKG
                     MQMGRAAVHRQQALVLINEDNAKSEDVVQLALHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
BASE COUNT         1109 a         1053 c          960 g         1156 t
ORIGIN      
        1 tccatctgag cagcaccggt gatcatgttt ttaacatagt cggcgtgccc cgggcagtct
       61 acgtgtgcgt agtgacgggt cggggtgtcg tattcaacgt gagaagtgtt gatggtgata
      121 ccacgagcct tttcttccgg cgcgttatcg atctggtcga atgcgcgagc agcaccgccg
      181 taggttttag ccagtacggt agtgattgca gcggtcagcg ttgttttacc atggtcaacg
      241 tggccgatag taccgacgtt aacgtgcggt tttgtacgtt caaacttttc tttagacatc
      301 gattgtccct ctaagacacg gataaatcgg tgatatcacc acatcaacca ggcaacatgc
      361 ccgacttgtt gaatgcaata aacagaagga aaaaacaggg aggagaaaag aagtggtgct
      421 gataggcaga ttcgaactgc cgacctcacc cttaccaagg gtgcgctcta ccaactgagc
      481 tatatcagca catcttggag cgggcagcgg gaatcgaacc cgcatcatca gcttggaagg
      541 ctgaggtaat agccattata cgatgcccgc atcctggaac tcggctacct gattttcatt
      601 ctgcactgaa tatcgagaga agctctcttt attcgagccg gtaagcgaac ttatcgtctc
      661 gggctacgcc atcgcgtggc cgaaattggt ggtgggggaa ggattcgaac cttcgaagtc
      721 tgtgacggca gatttacagt ctgctccctt tggccgctcg ggaaccccac cggacttgat
      781 ggtgccgact accggaatcg aactggtgac ctactgatta caagtcagtt gctctaccta
      841 ctgagctaag tcggcatcaa gtagcgcgca ttctatggag acatgcgagt tcatgcaact
      901 aaaaaattgc ataatttgtt ttattggtca cattttatgc gacacgatga agaaacagcc
      961 gaacggaggg cagattagca cactttttca acatcattgt gctcaacaat gtgctcctgc
     1021 taaaccataa ttctttttat cagatggaat atctgtcaca ttgcttttca acgatagctt
     1081 cctgggagag attttttctt attattcctc cccatctggt gttaccctcc tgcccattaa
     1141 cccattcaac agaactgtga cgcgccatgg caaatatcgc tttgccgata gagctatgac
     1201 cgccagaaac atgcttatga gtataaaaga gcaaacgtta atgacgcctt acctacagtt
     1261 tgaccgcaac cagtgggcag ctctgcgtga ttccgtacct atgacgttat cggaagatga
     1321 gatcgcccgt ctcaaaggta ttaatgaaga tctctcgtta gaagaagttg ccgagatcta
     1381 tttacctctg tcacgtttgc tgaacttcta tataagctcg aatctgcgcc gtcaggcagt
     1441 tttggaacag tttcttggta ccaacgggca acgcattcct tacattatca gtattgctgg
     1501 tagtgtcgcg gtggggaaaa gtacaaccgc ccgtgtattg caggcgctat taagccgttg
     1561 gccggaacat cgtcgtgttg aactgatcac tacagatggc ttccttcacc ctaatcaggt
     1621 tctgaaagaa cgtggtctga tgaagaagaa aggcttcccg gaatcgtatg atatgcatcg
     1681 cctggtgaag tttgtttccg atctcaaatc cggcgtgcca aacgttacag cccctgttta
     1741 ctcgcatctt atttatgatg tgatcccgga tggagataaa acggttgttc agcctgatat
     1801 tttaattctt gaagggttaa atgtcttaca gagcgggatg gattatccac acgatccaca
     1861 tcatgtattt gtttctgatt ttgtcgattt ttcgatatat gttgatgcac cggaagactt
     1921 acttcagacg tggtatatca accgttttct gaaattccgc gaaggggctt ttacagaccc
     1981 ggattcctat tttcataact acgcgaaatt aactaaagaa gaagctatta agactgccat
     2041 gacattgtgg aaagagatca actggctgaa cttaaagcaa aatattctac ctactcgcga
     2101 gcgtgccagt ttgatcctga cgaaaagtgc taatcatgca gtagaagagg tcagactacg
     2161 caaataattt tcaggggagc taatgctccc ctttcttatt tttctgcact acgcagggat
     2221 atttcaccgc ccatccaggg ttttattatt ccatcctgct caagtaataa agcaccctgt
     2281 ttgtctattc cgcgtgaaat gccaaatatt tctttatcac caatgataag tttcactggg
     2341 cgattaataa aattatccaa cttttcccag cgcgaaagat aaggtgccaa tccttcttgc
     2401 tcgaagagtt ccagcgccgc gcgtaattca cgtatcagca tggccgcaag actattacga
     2461 tcgagattga tcccggcttc ctgcagcgtg atccaccctt gattaacgac actctcttca
     2521 acacgacgca ttgccatgtt gatccctgcg ccaatgacta tttgcgccgc atcgccggtt
     2581 ttgccagtca gctccacaag aatgcctgcc agcttgcgat cctgcagata gaggtcatta
     2641 ggccatttaa cacgaacttt atctgcaccc agcttgcgta atacttccgc catcacgata
     2701 ccgataacca gacttaaacc aatcgccgcc gccgggcctt gttccagacg ccagaacatc
     2761 gacaaatata agtttgcgcc aaaaggcgaa aaccatttcc gaccccggcg accacggcca
     2821 gcctgctggt attctgcaac acaggcatcg cccgatttaa gctctccgat acgatcaaga
     2881 aggtactgat tcgtggagtc aataacgggc agcacagtta cactaccgcc atccagctga
     2941 cccaatatct gttcagcatt aagtaactgg ataggctcag gcaggctgta tcctttaccc
     3001 ggaacggtaa agacatcaac gccccagtca cgcagtgtct gaatgtgttt attaatagcc
     3061 gcccggctca ttcctaacga ttcacccaac tgctcaccag agtgaaattc gccattcgct
     3121 aacagcgcga ttaatttcag cggaacggta ttatccttca tgaaatcgtc tccactgcgc
     3181 taacttcacc tgatgcacca ataaagcgaa cttcaggctc aagccagaca ttaaattttt
     3241 cacccacttt ttgtcttaca tgaagtgcca gttgcaccac atcttcgctt tttgcattgt
     3301 cttcattaat gaggactaac gcctgttgac ggtgcaccgc agccctaccc atttgcatcc
     3361 cttttagctg gcactgatcg ataagccaac ctgctgccag ttttactgaa ccatccgcct
     3421 ggggataatt tggtgctgtt ggaaattgtg ccagtaatac tttagccgtt tcggcagata
     3481 caacagggtt tttgaagaaa ctaccggcat tgccattcac ttttggatca gggagtttgg
     3541 tggtgcgcat atgacacacc gcattaaata cttgctgtgg cgttactgtt gtaggatcca
     3601 gacgagttaa gtcaccatac gtcagtacag gttgccactc ttttggcaga cgcaggccta
     3661 cggctacaat agcgaagcga tcctggtatt catgtttaaa aatactgtcg cgatagccaa
     3721 aacggcactc tttggcagtt aagcgcactt gcttgcctgt cgccagttca acacaatcaa
     3781 cataagcgca aactcgctgt aattctacgc cataagcacc aatattctgg ataggtgatg
     3841 agccgacaca accaggaatt aatgccagat tttccagacc aggcatacct tcctgcaaag
     3901 tgtattttac aaggcgatgc cagttttctc cggctcctac atgtaaatac cacgcatcag
     3961 gttcatcatg aatttcgata cctttgatcc ggttgatgat caccgtgccg cgatagtctt
     4021 ccagaaaaag tacattactt ccttcaccca gaataagaac gggttgtcct tctgcggttg
     4081 catgctgcca ggcattgagt aattgttgtt cgtcttcggc acatacaatg tgctgagcat
     4141 tatgatcaat gccaaatgtg ttccagggtt ttaaggagtg gttcatagct gctttcctga
     4201 tgcaaaaacg aggctagttt accgtatctg tggggggatg gcttgtagat atgacgacag
     4261 gaagagttta tagaaacg
//
LOCUS       DAPOXO010000186         4255 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.186, whole genome shotgun sequence.
ACCESSION   DAPOXO010000186 DAPOXO010000000
VERSION     DAPOXO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4255
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.186"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            187..4026
                     /locus_tag="ROH59_004999"
     CDS             187..4026
                     /locus_tag="ROH59_004999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX4807362.1"
                     /translation="MCSKRNIGDMKITVLNQRYKKHFGYPHILMGDVKVTVSAMIACA
                     VLLHPNKLFASVAGTSLPYQTYRDFAENKGEFRPGAENVPLYDKNGNPVTTLNKAPMI
                     DFSSNDSTGVATLVSPQYVVSVKHNVGYQYVKFGYADDSSYALVDRNNHWRDFHTPRL
                     NKIVTEVTPLDITNAGTAKGTYQNADRFPVFYRVGTGTQYVKDTNGKITYLMGAYSYK
                     TGGIVNTPAISDWSFVTNTTNTPLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSYAG
                     VNGNTNWYTIIPAGDVKNTMKQDADAPVNTKQGEGDIHWSYDEKTGLGSLTQGSTSWE
                     MHGNLGATWPASLNSGKDLTFQGGGTVVLENTVNQGAGTLTFDDDYIVKPVDTQTWKG
                     GGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADD
                     NGLSQAFSSVSIVSGRPTLVLNDDKQINPDNIKWGYHGGKLDINGNSLTFHKLNGADD
                     GAILTNSGSMANVNLDFNSPDTTATIANIWHGHFTGNLNINNEVTAGTQNDFAIDGGV
                     NAQGSITQQNGRLFMQGHPVVHAVSSQDVANKLKALGDNSVLTQPVSFTQNDWENRQF
                     SMAELNLQNAEFNLARNASLNTRINAEHSTVTLGSEDLYIDLNDGNGVATKPTLGKSK
                     ATAEDDQSRFNGHVQLQQGSALTINEHFAGGIDSADSATTITSTDTTLNQLSRFTQSS
                     LSLGEGAKLTATAGLLSDGTVSSNAGASLSLLSDQPGTMYSAQSWELSGQDTSLNVGA
                     GGIITGDINANDAASISFGTTDINQSTNYYGNINAPLASVTMKDTAWQVNKQSVAKSL
                     TLNGSTLSFNRFGQGGLTSDTLEATNSSFIINADGKAADTVTVNQALTGGNNTLVVIP
                     TTNSVKQGGDPVSLVTAPKNTQSNIFTLNPVSINAGFHSFTPQLDVLETDVNKQWRLE
                     GFYIQPDKAALRTGKSFMDLGYKNFITEINNLNDRMGDLRHTHGETGAWARLNSGSGS
                     ATDGFTGSYTHLQIGADRKHIIEGGELFTGVTATFTSSNNRGTGWSGRTKSTGIGVYA
                     SAMFDSGLYVDTIGKYLRHDNHYSSSALGMPEQDYGSHSWYLGAEAGWRFSLPDETYI
                     QPQTELIYGTVSENQFAWQFNGGEIYMQRKQMQPLIGRTGIEFGKTFRGKDWEMTALT
                     GINYQYDLFKPTVTAFKDLAGDTYINNGKDSRVVFNVGVNTKIKENTRISLNVERSEF
                     GSYNIDKLINANIRYTF"
BASE COUNT         1287 a          803 c         1001 g         1164 t
ORIGIN      
        1 ttttgctgaa ttgtcattcc ttaagtacaa aatagcaatt ctaaaaaata gaatattttg
       61 ataataaaca ataaaatata tgcgtgaggg ttgactctga gcaatgcttg gatttattag
      121 ttttaagatc tttcgagtca gaagatatat gaatagatag aatagaaatt caattgtcgg
      181 aatgaaatgt gttcaaaaag aaatataggt gatatgaaaa ttacagtcct taatcagcga
      241 tataaaaaac attttggtta tcctcatatt ctgatgggtg atgtaaaagt aactgtttca
      301 gcaatgattg cttgcgctgt tttattgcac ccaaataaat tgtttgcctc cgtcgctgga
      361 acctcacttc cctatcaaac gtatcgtgat tttgctgaga ataagggaga gttccgtcct
      421 ggcgcagaaa atgttcctct atatgataaa aatggcaatc ccgtcacgac gctgaataag
      481 gcacccatga ttgacttcag ctctaatgac tcgactgggg ttgcaacact ggtttcgcca
      541 cagtatgtcg tcagcgttaa acacaatgtt ggttatcaat atgtgaaatt tggctatgca
      601 gatgattcat cctatgccct tgttgacaga aataaccact ggagagattt ccacactccc
      661 cgtctcaaca aaattgtcac cgaggttaca cctctggata taaccaatgc gggtacagct
      721 aagggaacct atcaaaatgc tgaccgtttc cctgtgttct atcgagtagg tacgggaact
      781 caatatgtaa aagatactaa cggaaaaatc acctatttaa tgggagccta ctcgtataaa
      841 acaggtggaa tagtaaatac gccggctata tctgactgga gttttgtcac gaataccact
      901 aatactccac tctcaaccta cggcactccc ggtgacagtg gctctcctct ttttgcctgg
      961 gatgcagacc aaaataaatg ggttttgtta gccgttctca attcatatgc aggggtcaat
     1021 ggcaatacta actggtacac aataattcct gctggtgatg taaaaaatac gatgaaacaa
     1081 gatgccgatg caccagtaaa tacaaaacaa ggtgaagggg atattcattg gtcatatgac
     1141 gaaaaaacgg gacttggttc attaacccag ggaagcacat catgggaaat gcatggaaat
     1201 ttgggggcaa catggcctgc ttcgcttaat agtggtaaag atctaacttt tcagggcggc
     1261 ggtactgtag tgttagaaaa taccgttaat cagggggctg gcacacttac ttttgatgat
     1321 gattatattg tcaagcccgt tgatactcag acatggaaag gcggcggaat tattgttaat
     1381 ggtgaacatc ttgttgactg gcagattaat ggggttactg gtgatagttt gcataaactg
     1441 ggtacgggta cgttaaaaat taacggtacc ggtgtaaacc caggaagctt aagtgtggga
     1501 gacggaaccg ttatattggc acagcgtgct gatgataacg gactgagcca ggcgttcagt
     1561 tctgtcagta ttgtaagtgg gcgtcctact ctggtgctaa acgacgacaa acaaattaat
     1621 ccggataata tcaaatgggg ctatcatggc ggcaagctcg acattaatgg aaacagtttg
     1681 acttttcata aacttaacgg ggctgatgat ggagctatac tgactaacag tggctccatg
     1741 gctaatgtta atctggattt caacagccca gatacaacag ccacgattgc taatatctgg
     1801 cacggccatt tcaccggtaa tctaaatatc aataatgagg ttaccgcagg aacacagaat
     1861 gatttcgcta ttgatggtgg agtgaatgct caggggagta taacccagca aaatggtcgg
     1921 ctatttatgc aaggacatcc ggttgttcac gccgtcagca gtcaggacgt agcaaataag
     1981 ctaaaggcgc tgggtgacaa ttcagtactg acccaaccag tgtcatttac tcagaacgat
     2041 tgggaaaatc gacagttcag tatggcggag cttaacttac aaaatgctga atttaacctt
     2101 gcaagaaacg ccagccttaa taccagaatt aatgccgagc attctaccgt gacgttaggt
     2161 agtgaggatc tttacattga tctcaatgac gggaatggcg tggcaaccaa accaacattg
     2221 ggtaagtcaa aggcaaccgc tgaagatgat cagagtcgtt tcaatggaca tgtacagttg
     2281 caacaaggat cggcactaac tattaatgaa cattttgccg gcggtattga tagtgcagat
     2341 agtgcgacga cgataacctc tacagatacc acgcttaatc agctcagccg tttcacccaa
     2401 tcttctttgt cattaggtga aggggcaaaa ttgaccgcta cagccggatt actttctgac
     2461 gggacggtaa gcagtaatgc cggggcgagc ctttccttgc tatcagacca gcctggaacg
     2521 atgtattccg cccaaagctg ggagcttagc gggcaagaca cgagcttaaa tgttggcgcg
     2581 ggtgggatca tcactggaga tatcaatgcc aatgatgcgg ccagcattag ctttggcacg
     2641 actgatatta accaatccac aaattactat ggaaatatca acgcgccgtt ggcaagtgta
     2701 acaatgaagg acactgcctg gcaggtaaac aagcagtcgg tggctaagtc gctcactttg
     2761 aatggttcaa cactgagctt taatcgtttc gggcaagggg gactgacgtc agatacgctg
     2821 gaggccacta acagttcgtt cattatcaat gccgatggta aagcagcaga tacggtgacg
     2881 gtaaaccagg cattgacagg ggggaataac acactggttg ttattcctac gacaaattca
     2941 gtaaaacagg gcggtgaccc tgtgtcattg gttactgccc cgaaaaatac acaaagcaat
     3001 atatttacac ttaacccggt ttcaataaat gcagggttcc atagttttac accgcaactt
     3061 gatgtgttgg agaccgacgt taataagcaa tggcgtctgg agggatttta catacagcct
     3121 gataaagccg ctttgcggac aggcaagagt tttatggatc tcggttataa aaactttatt
     3181 acagaaatta ataatctgaa tgatcgtatg ggggacttac gccataccca tggtgaaact
     3241 ggggcatggg ctagacttaa cagtggttcg ggctcagcta ctgatggatt taccggaagt
     3301 tatacgcact tgcaaattgg ggcagacagg aaacatataa ttgaaggcgg agagttattt
     3361 actggagtaa cggcgacatt tacaagcagt aataaccggg gaactggttg gtcgggaaga
     3421 accaaatcaa cgggtattgg tgtgtacgct tcagctatgt ttgactctgg actctatgta
     3481 gatactatcg ggaaatattt gcgtcatgac aatcattact catcaagtgc gttaggaatg
     3541 ccagaacaag attatggctc gcactcctgg tatttgggcg ctgaggccgg ttggcgtttt
     3601 tccttacctg acgaaacata tatacagccg caaacagagt tgatctacgg tactgtatct
     3661 gagaatcagt ttgcctggca attcaatggg ggtgagatct atatgcaacg taagcagatg
     3721 caaccattga ttggtcgcac aggaattgaa tttggcaaaa cattccgcgg caaagactgg
     3781 gaaatgacag cgctgactgg gattaattat cagtacgatt tatttaagcc tactgtgaca
     3841 gcgttcaagg atctggcagg tgatacatat attaataatg gtaaagatag cagagtggta
     3901 ttcaatgtcg gggtaaatac taaaattaaa gaaaacacta ggataagtct gaatgtggag
     3961 cgttctgagt tcggttcata caatattgat aagttaataa atgctaatat tcgttataca
     4021 ttctgagcag gagagtagat aaaaaagaaa acctgaacat attgttcagg ttttcttatt
     4081 gatttattgt tatagctagt caaatatgct tatctattgg atattctgga gtgtaaaatt
     4141 ttatcttatg ctgctatttt ttagagtggc tttattcttt actttagatt atagttggat
     4201 tcagttcagg tttctaatat tttatatgtg ctatgaccgt tgcgctaata atggt
//
LOCUS       DAPOXO010000187         4226 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.187, whole genome shotgun sequence.
ACCESSION   DAPOXO010000187 DAPOXO010000000
VERSION     DAPOXO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4226
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.187"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..326
                     /locus_tag="ROH59_005000"
     CDS             <1..326
                     /locus_tag="ROH59_005000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX4807363.1"
                     /translation="RPPAGLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRKGNCYDNA
                     PMESFWGTLKNESLSHYRFNNRDEAISVIREYIEIFYNRQRRHSRLGNISPAAFREKY
                     HQMAA"
     gene            complement(494..3205)
                     /locus_tag="ROH59_005001"
     CDS             complement(494..3205)
                     /locus_tag="ROH59_005001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDX4807364.1"
                     /translation="MNAIIPHKRRDGRSSFEDLIAYTSVRDDVQENELTEDSEIKSDV
                     PHRNRFRRLVDYATRLRNEKFVSLIDVMKDGSQWVNFYGVTCFHNCNSLETAAEEMQY
                     KADKAVFSRNDTDPVFHYILSWPAHESPRPEQLFDCVRHTLKSLELSKHQYVAAVHTD
                     TDNLHVHVAVNRVHPVSGHINRLSWSQERLSRACRELELKHGFAPDNGCFVHAPGNRI
                     VRKTALVRERRNAWRRGKKQTFREYIAQMSIAGLREEPAQDWLSLHKRLASDGLYITM
                     QEGELVVKDGWDRAREGVALSSFGPSWTAEKLGRKLGEYQPVPTDIFSQVGTPGRYDP
                     EAINVDIRPEKVAETESLKQYACRYFAERLPEMARNGELESCLDVHRTLAKAGLWMGI
                     QHGHLVLHDGFDKQQTPVRADSVWPLMTLDYMQDLDGGWQPVPKDIFTQVIPGERFRG
                     RNLGTQAVSDYEWYRMRMGTGPQGAIKRELFSDKESLWGYTTVQCESLIEDMIAGGNF
                     SWQACHEMFARKGLMLQKQHHGLVIVDAFNHELTPVKASSIHPDLTLSRAELQAGPFE
                     IAGADIFERVKPECRYNPELAASDEVEPGFRRDPVLRRERREARAAAREDLRARYLAW
                     KEHWRKPDLRYGERLREIHAACRRRKAYIRVQFRDPQLRKLHYHIAEVQRMQALIRLK
                     ESVKEERLSLIAEGKWYPLSYRQWVEQQAVQGDRAALSQLRGWDYRDRRKDKRRTTNA
                     DRCVILCEPGGTPLYEDTGVLEARLQKDGSVRFRDRRNGELVCVDYGDRVVFYHHQDR
                     NELVDKLNLIAPVLFDREPGMGFEPEGSYQQFNDVFAEMVAWHNAAGITGNGHFVISR
                     PDVDLHRQRSEQYYHEYIRQQKSISGGHGASYAPVQDNEWTPPSPGM"
     gene            complement(3217..3549)
                     /locus_tag="ROH59_005002"
     CDS             complement(3217..3549)
                     /locus_tag="ROH59_005002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nikA protein"
                     /protein_id="HDX4807365.1"
                     /translation="MSEKKTRTGSENRKRIVKFTARFTEDEAEIVREKAESSGQTVST
                     FIRSSSLDKVVNCRTDDRMIDEIMRLGRLQKHLFVEGKRTGDKEYAEVLVAITEYVNA
                     LRRDLMGR"
     gene            3782..4117
                     /locus_tag="ROH59_005003"
     CDS             3782..4117
                     /locus_tag="ROH59_005003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
                     /protein_id="HDX4807366.1"
                     /translation="MASKKFYSDDDIQLAKAALSELPDLTAQRKTLRDFLDAIRDDII
                     VLVRTKGYTLADVRDTLKNAGYEVGEKALRDIIREAESKKLSRRSSSKTAPKKTDSGS
                     KDGIDMNNN"
BASE COUNT         1067 a         1179 c          900 g         1080 t
ORIGIN      
        1 agcgcccacc tgccgggcta atccaccact ctgatcgagg ttcacagtac tgcgcatacg
       61 attaccgggt catacaggag cagtttggtc tgaaaacatc aatgtcgcgt aaaggtaact
      121 gttacgacaa cgctccgatg gaaagcttct ggggaacgct gaaaaatgag agcctgagcc
      181 actatcgttt taataaccgg gatgaagcca tctcagtaat acgggaatac attgagattt
      241 tctacaatcg tcagcgtcgt cactctcgtc tggggaatat ctccccggca gccttcaggg
      301 aaaaatatca tcagatggct gcttaaaaaa agaacaaatg gtagtgtccg ctattgccag
      361 tacaagcata acgattttct ttacccccat atattgctcc tcaatccata tagatctcag
      421 taccatagct ctgtcagagc aaagaaaatc ttaactaata caagttaaga tttttaatat
      481 ccactcctca tccctacatt ccaggtgatg gtggcgtcca ctcattatcc tgaactggag
      541 cataagatgc gccatgcccc ccggatatgc ttttctgttg cctgatatat tcgtggtagt
      601 actgttcact acgctgacga tgtaaatcca catccgggcg gctgattaca aagtgtccat
      661 ttccggttat tccagctgca ttatgccagg ccaccatttc cgcaaataca tcattaaact
      721 gttgatatga gccttccggt tcaaaaccca ttcctggctc acgatcaaac aatacaggag
      781 caatcagatt cagcttatcc accagttcat ttctgtcctg atgatggtag aacaccacac
      841 ggtccccata atccacacag actaactcgc cattcctccg atcacgaaaa cgcacactgc
      901 catctttctg cagacgggct tcgagaacgc cagtgtcttc ataaagtgga gttcctcccg
      961 gttcacagag aatcacgcag cggtcggcat tcgttgttcg tcgcttgtct ttgcgacgat
     1021 cacgataatc ccagccacgt aactgtgata atgcagctct gtctccctgt accgcctgtt
     1081 gctccaccca ctgccggtag gacaaaggat accacttacc ctccgcaatc agtgacaacc
     1141 gctcttcctt cacactctcc ttcagcctga tcagcgcctg catacgctgc acttccgcaa
     1201 tatggtaatg cagcttacgc aattgtggat cccggaactg cacacggata tacgccttgc
     1261 gccgacggca ggcagcatga atttcccgta accgttctcc gtaacgtaag tcgggtttac
     1321 gccagtgctc cttccatgca agataacgcg cgcgcaaatc ttcccgcgca gctgcacggg
     1381 cttcacggcg ttcacgacgc agtacaggat cgcgccggaa gccgggttcc acttcatcgc
     1441 tggcagcaag ttccggattg tagcgacatt caggcttcac ccgttcaaat atatctgcac
     1501 ctgcaatctc aaatggccct gcctgcagct cagccctgga taacgtcaaa tccgggtgga
     1561 tactgctggc cttcactggt gtgagctcat gattaaacgc atccacaatc acaagaccat
     1621 gatgctgttt ctgcaacata agccctttac gcgcaaacat ctcatggcac gcctgccagc
     1681 tgaaattccc gcccgcgatc atatcttcaa tcaacgactc acactgaaca gtcgtgtacc
     1741 cccacagact ttccttatca gaaaacagtt cgcgctttat tgctccctgt ggacctgtcc
     1801 ccatccgcat acgataccat tcgtaatcac tgacagcctg agtaccaaga ttacgtcccc
     1861 ggaatcgttc tccgggtata acctgagtaa aaatatcctt cggtacaggc tgccatccac
     1921 catccagatc ctgcatataa tccagcgtca ttaacggcca cacactgtct gcacgtactg
     1981 gtgtctgttg tttatcaaat ccatcatgca gtaccagatg cccgtgctgg atccccatcc
     2041 ataatccagc ctttgccaga gttctgtgca catccaggca actttccagc tcaccatttc
     2101 tcgccatttc cggtaagcgt tcggcaaaat aacggcaggc gtactgtttc agactctccg
     2161 tttctgccac tttttccggc cggatatcaa cgtttatggc ttccggatca taacgaccgg
     2221 gtgtccccac ctgactgaaa atatctgtcg gtacaggctg atattccccc agtttccgcc
     2281 ccagtttttc agctgtccat gacggtccga acgaactgag tgcaacacct tcccgcgctc
     2341 tgtcccagcc atccttcacc accagttccc cttcctgcat cgtgatatac agaccatcac
     2401 tggccagccg tttatgcaaa gacaaccagt cctgtgcggg ctcttcacgc agcccggcaa
     2461 tcgacatctg cgcaatatat tccctgaacg tctgcttttt cccgcgtcgc caggcattac
     2521 ggcgctcacg taccagcgct gttttgcgca caatacggtt gccgggtgca tgcacaaagc
     2581 agccattatc aggcgcgaat ccgtgcttaa gttcaagttc acgacatgca cggctgagcc
     2641 tttcctgact ccaggaaaga cgattaatat gaccactaac aggatgaaca cgattcactg
     2701 cgacatgtac atgcaggtta tccgtgtccg tatgaacggc agccacgtac tgatgttttg
     2761 agagttcaag ggatttcagt gtgtgacgca cacagtcaaa aagctgctca ggacgcgggc
     2821 tttcatgcgc aggccaggaa agaatgtagt ggaaaacggg gtctgtatca ttacgggaaa
     2881 aaacagcttt gtccgccttg tactgcatct cttcagcagc tgtttccagt gaattgcagt
     2941 tatggaaaca ggttacgcca tagaaattta cccactgact gccgtctttc atcacatcaa
     3001 tcagggagac aaatttttcg ttacgcaggc gtgttgcata atcaacaagc cgtctgaaac
     3061 ggttgcggtg agggacatca ctcttgattt cgctgtcttc tgtgagctca ttttcctgca
     3121 catcatcccg cacagacgtg tacgcaatca ggtcttcaaa ggaagacctg ccgtcacgtc
     3181 ttttgtgcgg aataatggca ttcatcagca gttatctcag cgtcccatta agtctcttcg
     3241 cagagcattg acatattcag taatggcaac aagaacctct gcatactcct tatcaccagt
     3301 gcgttttccc tccacaaaca gatgcttctg aaggcggcca agacgcataa tctcatcaat
     3361 catacggtcg tcagtacggc agttaaccac cttatccagt gaagaacttc gtataaatgt
     3421 tgaaaccgtc tgtccacttg actccgcttt ttctcttacg atttcagcct catcctccgt
     3481 gaatctcgcc gtgaatttta caattctctt cctgttctca ctgcccgttc gggttttctt
     3541 ctcactcatg gtctgctcct taccggggtg tcggggcaaa gccctgacca ggtggcattt
     3601 gtctgattgc gcgtgcgcgg tccgacaaat gcacatcctg tcctgttttt caggccatta
     3661 tagcctgtta tttttgtgca tcatagtctt atgcagacgg cagaggcagg gcgcagccct
     3721 gccaggagtc agtttttgat gataaaatca ggcttcaaca tgaaacggag agacagtgcc
     3781 aatggcttct aaaaaatttt actcagatga tgacatccag ctggcaaaag ctgccttatc
     3841 ggaattgccg gacctcaccg ctcaacggaa aacattgcgt gattttcttg atgccattcg
     3901 tgatgacatc attgtcctgg taaggacaaa gggttataca ctggcagatg ttcgtgacac
     3961 gctcaaaaat gcagggtatg aagtaggaga gaaggcactt cgtgacatta ttcgggaagc
     4021 agaatcgaaa aaactatccc gccgttcttc ctctaaaaca gcacctaaaa agacagattc
     4081 aggcagtaaa gatggcatcg atatgaacaa caattgatgt gacaatgtca catcgtgttc
     4141 tgagattatg atgattacag aaaaaaaagc cccggcataa ataccagggc ttttctgttt
     4201 aatcagactc gtggcggcaa tgcacc
//
LOCUS       DAPOXO010000188         4132 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.188, whole genome shotgun sequence.
ACCESSION   DAPOXO010000188 DAPOXO010000000
VERSION     DAPOXO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4132
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.188"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            192..1874
                     /locus_tag="ROH59_005004"
     CDS             192..1874
                     /locus_tag="ROH59_005004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310130.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HDX4807367.1"
                     /translation="MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAF
                     SDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAI
                     EAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGI
                     PLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQ
                     NRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPF
                     MLYLAYNAPHLPNDNPAPEQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQ
                     YDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKL
                     ISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQNKKQGEPHKNLTWITSYSHWFDEE
                     NIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTD
                     LQQKDNLAAANPQVVKEMQGVVREFIDNSQPPLSEVNQEKFNNIKKALSEAK"
     gene            1926..3083
                     /locus_tag="ROH59_005005"
     CDS             1926..3083
                     /locus_tag="ROH59_005005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HDX4807368.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQIEFNTLTVI
                     NNINVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRISAKCQQCVYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN"
     gene            3095..4006
                     /locus_tag="ROH59_005006"
                     /pseudo
     CDS             3095..4006
                     /locus_tag="ROH59_005006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416011.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
BASE COUNT         1264 a          889 c          850 g         1129 t
ORIGIN      
        1 caatagatta gttgtttatc ggcgagaaat tacttagtag aacagaaagt aatgtcaacg
       61 cgttatggac tgttatttcc ctttttttag ctaaatctgc tatctcttta tgtgactaac
      121 ttcacttaca ttcacttatt tctcttcgta aaattacttt ggaattaagt acaataagaa
      181 gaggaacatt tatgaagtct gcattaaaga aaagtgtcgt aagtacctcg atatctttga
      241 tactggcatc tggtatggct gcatttgctg ctcatgcggc agatgatgta aagctgaaag
      301 caaccaaaac aaacgttgcg ttctcagact ttacgccgac tgaatacagt accaaaggaa
      361 agccaaatat tatcgtactg accatggatg atcttggtta tggacaactt ccttttgata
      421 agggatcttt tgacccaaaa acaatggaaa atcgtgaagt tgtcgatacc tacaaaatag
      481 ggatagataa agccattgaa gctgcgcaaa aatcaacgcc gacgctcctt tcattaatgg
      541 atgaaggcgt acgttttact aacggctatg tggcgcacgg tgtttccggc ccctcccgcg
      601 ccgcaataat gaccggtcga gcgcccgccc gctttggtgt ctattccaat actgatgctc
      661 aggatggtat tccgctaaca gaaactttct tgcctgaatt attccagaat catggttatt
      721 acactgcagc agtaggtaaa tggcacttat caaaaatcag taatgtgccg gtgccggaag
      781 ataaacaaac gcgtgactat catgacaact tcactacctt ttctgcggaa gaatggcaac
      841 cgcaaaaccg tggctttgat tactttatgg gattccatgc tgcaggaacg gcatattaca
      901 actccccttc actgttcaaa aaccgtgaac gcgtccccgc aaaaggttat atcagcgatc
      961 agttaaccga tgaagcaatt ggcgttgttg atcgtgccaa aacacttgac cagcctttta
     1021 tgctttacct ggcttataat gctccgcacc tgccaaatga taatcctgct ccggagcaat
     1081 atcagaagca atttaatacc ggtagtcaaa cagcagataa ttactacgct tccgtttatt
     1141 ctgttgatca gggtgtaaaa cgcattctcg aacaactgaa gaaaaacgga cagtatgaca
     1201 atacaattat tctctttacc tccgataatg gtgcagttat cgatggtcct ctgccgctga
     1261 acggggcgca aaaaggctat aagagtcaga cctatcctgg cggtactcac accccaatgt
     1321 ttatgtggtg gaaaggaaaa cttcaacccg gtaattatga caagctgatt tccgcaatgg
     1381 atttctaccc gacagctctt gatgcagccg atatcagcat tccaaaagac cttaagctgg
     1441 atggcgtttc cttgctgccc tggttgcaaa ataagaaaca aggcgagcca cataaaaatc
     1501 tgacctggat aacatcttat tctcactggt ttgatgagga aaatattcca ttctgggata
     1561 attaccacaa atttgtccgc catcagtcag acgattaccc gcataacccc aacaccgagg
     1621 acttaagcca attctcttat acggtgagaa ataacgatta ttcgcttgtc tatacagtag
     1681 aaaataatca gttaggtcta tacaaactga cggatctaca gcaaaaagat aaccttgccg
     1741 ccgccaatcc gcaggtcgtt aaagagatgc aaggcgtggt aagagagttt atcgataaca
     1801 gccagccacc gcttagcgag gtaaatcagg agaagtttaa caatatcaag aaagcactaa
     1861 gcgaagcgaa ataactaaac ctttatgcgg cggatttttc cgccgcctta ttgagcgaga
     1921 tagcgatgca cgttacagcc aagccctcca gttttcaatg taatctcaaa tgtgattact
     1981 gtttttacct tgaaaaagag tcgcagttta ctcatgaaaa atggatggat gacagcactc
     2041 tgaaagagtt catcaaacaa tatatcgcag cgtctggcaa tcaggtctat tttacctggc
     2101 aaggcggtga acccactctg gctggcctgg attttttccg taaagttatt cactatcaac
     2161 aacgctatgc aggccaaaaa cgtattttta atgcattaca aacgaatggc attttattga
     2221 ataatgaatg gtgtgccttt ctcaaagaac atgagtttct ggttggtatc tcgatcgatg
     2281 gcccccaaga actacatgac cgttacagac gcagtaattc aggtaacggt acttttgcaa
     2341 aagtgatagc agccatcgag cgtctgaaat catatcaaat agagtttaat acgttaaccg
     2401 ttattaataa cattaatgtc cattaccctc ttgaggttta tcatttttta aaatctatcg
     2461 gcagtaaaca tatgcaattt atcgaattgc tcgaaaccgg gacgccgaat attgatttca
     2521 gtggtcatag tgagaacaca ttccgtatca ttgatttttc tgtgcctccc acggcttatg
     2581 gcaagtttat gtcaaccatt tttatgcaat gggttaaaaa cgatgtgggt gaaattttca
     2641 tccgtcagtt tgaaagcttt gtcagccgtt ttttggggaa tgggcatacc agttgtattt
     2701 tccaggagtc ctgcaaggat aatctggttg ttgaaagtaa tggagacatt tacgaatgcg
     2761 accattttgt ctatccacag tacaaaattg gaaacattaa taaatcggaa ctcaaaacga
     2821 tgaacagtgt acaactgaca gcgcaaaaaa aacggatttc agcgaaatgt cagcaatgtg
     2881 tatataaacc tatctgcaat ggtggttgcc ctaagcatcg tattactaaa gtaaacaatg
     2941 agactgtttc ctatttttgc gaaggttata aaatcctttt ttcaaccatg gtaccttata
     3001 tgaacgccat ggtggagtta gctaagaaca gagtaccgct ttaccacatt atggatgttg
     3061 caaaacaaat ggagaataat taataacgct cccccacagc acgattaacg acaatatttg
     3121 ggcatcgcta caaaatgctc aaattcaggc gttgaaaacg ctcgaccagc gtccagcgga
     3181 gaaattcgcc cagcagatgt atgagacgcg ctatgctgat aaccgcacga aattaccgca
     3241 agcaaatcag attgcacagt ttactgccgc agatgcactg gctgccgatc gccagttgtt
     3301 ttcatctcca gcggatatca cgtttgtcat tgtcggtaat gtcgcagaag acaaactcgt
     3361 ggcgttaatt acgcgttact taggatcaat caaacactct gattcgccat tagccgcagg
     3421 taaaccatta actcgcgcga cggacaacgc atcggttact gtaaaagaac aaaatgaacc
     3481 agtggcacag gtttcacagt ggaagcgtta taattcccgg actcctgtta atctggcgac
     3541 gcgtatggcg ctcgatgctt ttaacgtcgc actggcaaaa gatctacgca ttaatattcg
     3601 tgaacaggca tccggggcat acagcgtttc ttctcgcctc tcggttgatc ctcaggccaa
     3661 agatatcagt catttgctgg cttttacttg tcaaccagaa cgacatgatg aactgttaac
     3721 gttagcgaat gaagtgatgg ttaagcgtct ggccaaaggg atcagtgagc aagaactgaa
     3781 cgaataccag caaaacgttc agcgcagcct cgatatccaa cagcgtagcg ttcaacaatt
     3841 agcgaacacc attgtaaata gtcttattca atatgacgat cctgcagcat ggactgagca
     3901 ggagcaattg ttgaaacaaa tgacggtaga gaatgttaac actgctgtta aacaatatct
     3961 ttctcatccg gtgaatacct ataccggagt attattgcca aaataatcac agccccgtca
     4021 acacatcgtt ggcggggatt tcatcaatat tcgctatttt tatgtaataa ttttataaat
     4081 gtgttcaaag taaataaccg tgtaccaata atgatattat aaggtctgat tt
//
LOCUS       DAPOXO010000189         4130 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.189, whole genome shotgun sequence.
ACCESSION   DAPOXO010000189 DAPOXO010000000
VERSION     DAPOXO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4130
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.189"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..899
                     /locus_tag="ROH59_005007"
     CDS             <1..899
                     /locus_tag="ROH59_005007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HDX4807369.1"
                     /translation="FSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLLQI
                     TENIRSEQCPGVTAAGRGAVSPENIAFTRWLTHLQNGVLLDEQNCLMLHELWLQSGTG
                     QRRWEELPDDVRETITVHFTAKRGDWCDIWGNEDVSVWWNRLCDNVLPEKTMPFDLLT
                     VLPTRLDIEVNGFNGGVLNGVPSAYHWYTERYGVKWPCGYDLNISSQGDNFIQVDFDT
                     PWCQPESDVIAELSRRFSCTLEHWYAEQGCDFCGWQLYERGELVDVLWGELEWSSPTD
                     DDELPEVTGPAWIVDKVAHYGG"
     gene            complement(994..1329)
                     /locus_tag="ROH59_005008"
     CDS             complement(994..1329)
                     /locus_tag="ROH59_005008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807370.1"
                     /translation="MRTITTREQLLVNGKVRERIATHIVTGAHGYETLCTSGYNLQYN
                     KERVLIENCEKVADGELPVTCHTCFSIWQDVHRFKPGDFDTESGKGNFTDTELTKITI
                     GQEKTPNAC"
     gene            1667..2647
                     /locus_tag="ROH59_005009"
     CDS             1667..2647
                     /locus_tag="ROH59_005009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HDX4807371.1"
                     /translation="MRIFVDDGSTNIKLAWVEDGAVKTLISPNSFKPEWSMTLQGLTD
                     ATVPASANYEIDGEKYSFDQLSPDAVRTTETRYQYSDVNVVAIHHALMQSGIAPQPVD
                     IVVTLPLGEYLDENDQPNLANIERKKNNVRRTVTVQGRENFTIRKVSVLPESVPAGFD
                     VLKDLNDLESLLIVDIGGTTLDIAHVRSKMSGFTKTYCDPKTGVSIITEAVKHAMDVN
                     VSTRTSSYFADRLIQGRDDNEFLTRYIPNAEQRERILTVLRDREKKLHYRVADSVGRF
                     AGFTHVMVVGGGASLVAGAVKKATGVGDNRFFVSDNPQFDLVLGMMAMKG"
     gene            2650..3072
                     /locus_tag="ROH59_005010"
     CDS             2650..3072
                     /locus_tag="ROH59_005010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HDX4807372.1"
                     /translation="MADNRKCSFYIYPERNAADRVADRFLEKLPQKERGRAMRAMMLC
                     GAALMKQDERLPFLIAEFLTDSTSMQDIQRIISSTLPQQENGEVVRLLEAFLQSAGNN
                     AKAILPAVDSATQEISAPVDQNLLETRNNIKNLFPDDE"
     gene            3076..3387
                     /locus_tag="ROH59_005011"
     CDS             3076..3387
                     /locus_tag="ROH59_005011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807373.1"
                     /translation="MNSVKGRCCVLFSFPTKDVAGLLFLLRRQTRRGRNAACGQYPAS
                     GRARDGRFYRSRLASVAVYASPSPFSDERPSSRFRGIALPSKRRRLRYSTVGLTRYRT
                     R"
     gene            3463..>4130
                     /locus_tag="ROH59_005012"
     CDS             3463..>4130
                     /locus_tag="ROH59_005012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HDX4807374.1"
                     /translation="MSRFVLGNCIDVMARIPDNAIDFILTDPPYLVGFRDRQGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMSAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPALPQKPLPDVQGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DNWF"
BASE COUNT          939 a          967 c         1116 g         1108 t
ORIGIN      
        1 atttttctgg tgaaccagca cagatcgctg agattaaacg actggccagc ggtgcagtca
       61 caccgcttta tcgccgcgcc acaaatgaag gtattcagct gtttctggcc ggaagtgccg
      121 gacttctgca gatcactgaa aatatccgct ctgagcagtg ccccggagtg acggctgccg
      181 gacgtggtgc tgtatcaccg gaaaatatcg cgttcacccg ctggctgaca cacctgcaga
      241 acggtgtact gctggatgag caaaactgcc tgatgctgca tgaactctgg ctgcagagcg
      301 gtactggaca gcgtcgctgg gaagagttac cggatgatgt cagggaaact atcactgtgc
      361 atttcaccgc aaaaagaggt gactggtgtg acatctgggg taacgaggat gtatcggtgt
      421 ggtggaaccg tctgtgtgac aacgtactgc cggaaaaaac catgccgttt gacctgctga
      481 cggttttgcc gacccgcctg gatattgaag tgaatggctt taacggcggt gttctgaacg
      541 gtgttccttc tgcatatcac tggtatacag aacggtatgg cgtgaagtgg ccttgtgggt
      601 atgacctgaa tatcagtagt cagggagaca acttcattca ggttgatttc gacacgccgt
      661 ggtgtcagcc ggaaagcgac gttattgcag aattaagccg ccgtttcagc tgcacgctgg
      721 agcactggta tgccgaacag ggctgtgatt tctgtggctg gcagttgtat gagcgcggag
      781 agcttgttga tgtgctgtgg ggggagctgg aatggtcttc cccgacagat gatgatgagc
      841 tgccggaagt caccggacct gcgtggatag tcgacaaggt ggcgcattac ggtggatgaa
      901 gtatgacgga gacgggcggg caaccgcccg tttcttttcc ggtaaaggat gtcgccatgc
      961 tcctcttttt actgcgccgg ctgacgcggc acatcaacac gcattcggcg ttttttcttg
     1021 tccaattgtg attttcgtga gctccgtatc agtgaaattt ccctttcctg attctgtgtc
     1081 aaagtcacca ggtttgaacc ggtgtacatc ctgccatata gagaaacaag tgtggcaggt
     1141 gacaggcagt tctccatcag ccaccttttc gcagttttca atcagtaccc gttccttatt
     1201 gtattgtaag ttataaccac ttgtgcaaag cgtttcatac ccgtgagcgc ctgtcacgat
     1261 atgtgtggca atccgttccc tgacttttcc gttcactaat aactgttcac gtgtggtgat
     1321 cgttcgcatt ctcttcctca tcagctttcc tgtagaagcc tcctgactat aaggctccgg
     1381 atatcttacc cgctcatttt ggctggaggt agtggtggcg tcagaggatg aattactgac
     1441 attgtatatg aagctttgag ttttttctgg atttcatcag tgtttatctt tatttgttct
     1501 tgtttgttct cttttgtgct gttggtgtcg gtttttgtct gtgtttttct ttatttttcc
     1561 atttgtggcc gatatcaggt ctttaccgat acgttgtttt aggtgataat cgtttttgat
     1621 ctcgtatttt tctaaaaaaa tccattttat ttatgtgagg ttctagatgc gtatctttgt
     1681 agacgacggc tctaccaaca tcaaactggc ctgggttgaa gacggtgcag tgaaaacgtt
     1741 aattagtccg aatagtttta agccggaatg gtctatgacg ctgcagggac tgactgatgc
     1801 cactgtaccc gcttccgcaa actatgagat tgatggagaa aaatacagct ttgatcaatt
     1861 gagtccggat gcagtgcgca ccacagaaac gcgttatcag tacagcgacg ttaatgtggt
     1921 tgctattcat catgcgttga tgcagtcagg tattgctcca caacctgttg atattgttgt
     1981 gactttacct ttaggtgagt atctggatga gaacgatcag ccaaatctgg ctaatatcga
     2041 acgtaagaaa aataatgtcc ggcgaactgt aacagttcag gggcgtgaaa actttaccat
     2101 tcgtaaagtc agtgtcttgc ctgagtccgt gcctgccggt tttgacgtgc tgaaagatct
     2161 gaatgatctg gagtcgctgt tgattgttga tatcggtgga acgacccttg atattgcaca
     2221 tgtccgcagc aaaatgtcag gtttcacaaa aacctattgt gaccccaaga ctggcgtctc
     2281 catcattact gaagcagtta agcatgcgat ggatgtgaat gtgagtacac gaaccagttc
     2341 ttattttgca gatcgtctaa tccagggccg ggatgacaat gaattcctga cccgttatat
     2401 cccgaatgca gaacagcgtg agcggatcct gacagtatta cgtgaccggg aaaaaaaact
     2461 gcattatcgt gtggcggatt cagtaggacg ctttgctggt tttactcatg ttatggttgt
     2521 tggcggtggt gccagccttg tggctggggc agtaaaaaaa gcgacaggag tgggtgataa
     2581 ccgtttcttt gtcagtgaca atcctcagtt cgatctggtg ttgggaatga tggcaatgaa
     2641 gggatgagta tggctgataa tcgtaagtgc tctttttata tttatccgga acgaaatgca
     2701 gctgatcggg tggctgacag gtttcttgaa aaattgcctc agaaagaacg tggtcgggca
     2761 atgcgggcca tgatgttgtg tggtgctgca ttgatgaagc aggatgaacg attgccgttc
     2821 ctgatagctg aattcctgac agacagcacg tctatgcagg atattcaacg aattatcagt
     2881 agtacgctac cacaacagga aaatggtgaa gtcgttcgtt tgctggaggc atttctgcag
     2941 tctgctggta ataatgcaaa agcgatcctg cctgcggttg attctgctac gcaagaaata
     3001 tctgctccag tcgatcagaa tctcctggaa acaagaaaca acattaagaa cttgtttccg
     3061 gatgatgaat aagaactgaa ctctgttaaa ggacgctgtt gcgtcctttt ttcttttccg
     3121 acaaaggatg tcgccgggct cctcttttta ctgcgccggc agacgcggcg cggcaggaac
     3181 gctgcctgtg gtcagtatcc cgcgtccggc cgggcacggg acgggcgctt ttaccgctcc
     3241 cggctggcgt cggtggcagt gtacgccagc ccgtcgccct tttctgatga acgcccttca
     3301 agccgctttc gcggcatagc cttgccgtca aaaagacgac ggctgcggta ttccacggtc
     3361 ggcctgaccc gttaccggac gcggtgaaca gcccacaggc agcggggaac gggcaccaca
     3421 ggggtgccct cccggtgccc tctgtaagag aaggagtttt gtatgtcccg ttttgtcctc
     3481 ggtaactgca tcgatgttat ggcccgtatc cctgataacg ccattgattt catcctcacc
     3541 gacccgccgt acctcgtcgg ttttcgtgac cgtcaggggc gtaccattgc cggcgataaa
     3601 accgacgaat ggttgcaacc ggcctgtaat gagatgtacc gcgtactcaa aaaagacgcg
     3661 ttaatggtga gcttctatgg ctggaatcgc gtcgatcgct ttatgtctgc ctggaaaaat
     3721 gcgggattca gcgttgttgg tcacctggtc ttcaccaaaa actacacatc gaaggccgca
     3781 tatgtgggct atcgccacga atgcgcctac atcctggcaa aaggacgtcc ggcgctgcct
     3841 cagaagccat tgcccgacgt gcagggctgg aaatattcag gcaatcgtca tcacccgact
     3901 gaaaagcccg ttaccagcct gcaaccgctc attgagagct tcacacaccc gaacgcgatt
     3961 gtgctggacc cgtttgcagg cagcggctca acctgtgtgg ccgccctcca gtccggacgc
     4021 cggtatatcg gtatcgagct gcttgaacag tatcaccgtg ccggacagca acgactggcc
     4081 gccgtgcaac gggccatgca gcagggggcc gcgaatgata actggtttga
//
LOCUS       DAPOXO010000190         4044 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.190, whole genome shotgun sequence.
ACCESSION   DAPOXO010000190 DAPOXO010000000
VERSION     DAPOXO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4044
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.190"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            73..789
                     /gene="nanC"
                     /locus_tag="ROH59_005013"
     CDS             73..789
                     /gene="nanC"
                     /locus_tag="ROH59_005013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HDX4807375.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
     gene            809..1915
                     /gene="nanM"
                     /locus_tag="ROH59_005014"
     CDS             809..1915
                     /gene="nanM"
                     /locus_tag="ROH59_005014"
                     /EC_number="5.1.3.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HDX4807376.1"
                     /translation="MNKTITALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGDLYVFGGIGKNSKGLTQ
                     VFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGDNLKWNRLAPVSSPDGVAGGFAGISNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGESAGGKAVTDSVLISVKDNKVTVQN"
     gene            1979..2959
                     /locus_tag="ROH59_005015"
     CDS             1979..2959
                     /locus_tag="ROH59_005015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HDX4807377.1"
                     /translation="MNAIISPNYYYVLTVAGQSNAMAYGEGLPLPDREDAPHPRIKQL
                     ARFTHTHPGGPPCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGILIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPHNKFLGVCWMQGEFDLMTSDYASHPQHFNHMVEAFRRDLKQFHSQLNNIT
                     AAPWFCGDTTWYWKENFPHAYEAIYGNYQNNVLANIIFVDFQQQGERGLTNAPDEDPD
                     DLSTGYFGSAYRSAENWTTSLRSSHFSAAARRGIISDRFVEAILQFWRER"
     gene            complement(3542..>4044)
                     /locus_tag="ROH59_005016"
     CDS             complement(3542..>4044)
                     /locus_tag="ROH59_005016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA helicase"
                     /protein_id="HDX4807378.1"
                     /translation="LISAHTQISTLHGVEQHDGFLNKTLAGAQKKITIISPWLSWQKV
                     EQTGFLASMALARSRGIDITVVTDKNCNIAHVDDDKRQEKQHLLNDAVEKLNKMGIAT
                     KLVNRVHSKIVIEDEELLCVGSFNWFSAAREDKYQRYDTSLVYRGEGVKNEIKAIYGS
                     LDQRQL"
BASE COUNT         1173 a          889 c          910 g         1072 t
ORIGIN      
        1 tacacaacat aaatgctaat tgtttatgcg ggctttgtat tgctttctgt atcctacaaa
       61 tgagtgaaat ttatgaaaaa ggctaaaata ctttctggcg tattattact gtgcttttcg
      121 tccccattaa tttctcaggc tgcgacactg gacgtacgtg gtggatatcg tagtggaagc
      181 cacgcctatg agactcgact caaagtcagt gagggatggc aaaatggatg gtgggcaagc
      241 atggaaagta atacctggaa taccattcat gataataaaa aggaaaatgc cgcactcaat
      301 gatgttcagg ttgaagttaa ttacgcaatt aaacttgatg atcaatggac ggtacgcccg
      361 ggaatgttaa cgcattttag cagcaacggc acacgttacg gaccctacgt aaaactgtcc
      421 tgggacgcga caaaagatct taattttggc attcgctatc gttacgactg gaaagcttac
      481 cgacaacaag acttatccgg tgatatgtct cgtgataacg ttcatcgttg ggatggatat
      541 gtcacttacc atattaatag tgatttcacc ttcgcatggc aaacgacgct atacagcaaa
      601 cagaacgatt atcgctatgc aaaccataag aaatgggcga cggaaaatgc atttgttcta
      661 caataccata tgacgcccga tattacgcca tacatagaat atgactacct tgaccgtcag
      721 ggtgtttaca acggcagaga taatttatcg gaaaacagtt atcgcattgg tgtgtcattt
      781 aaactgtagt agacaggaga cagtcacaat gaataaaaca ataacggcgc ttgctatcat
      841 gatggcttca tttgccgcaa acgcgtctgt attaccggaa actcctgtgc catttaaaag
      901 tggtaccgga gcaattgata acgacactgt ctacattggt ttaggtagcg caggtacggc
      961 atggtacaag ctggatacac aggccaaaga taaaaaatgg acagcgttag ctgcattccc
     1021 tggtggacca agagatcaag caacctcggc atttattgat ggtgatctgt atgtgtttgg
     1081 cggcattggc aaaaatagca agggcttgac tcaggtattt aatgacgtac acaaatacaa
     1141 ccccaaaacc aatagctggg ttaaattgat gtcgcacgcg ccaatgggca tggcgggcca
     1201 tgtgactttt gtacacaacg gcaaagctta tgttactggc ggtgttaacc agaatatctt
     1261 caatggctat tttgaagatc tcaacgaggc tggaaaagat tcaaccgcta tagataaaat
     1321 caacgctcac tattttgaca aaaaagcaga agattatttc ttcaataagt ttctgttgtc
     1381 ttttgatccc tcaacccagc aatggagtta cgctggcgaa tctccctggt acggaacggc
     1441 tggtgcggcg gttgtgaata aaggtgataa aacctggctt attaatggcg aagccaaacc
     1501 cggattgcga acggatgccg tatttgaact tgatttcacc ggtgataatt taaaatggaa
     1561 taggcttgct cccgtctcat caccagatgg cgtcgctggc ggttttgcgg ggataagcaa
     1621 tgattctctt atatttgccg gaggggccgg attcaaaggt tcacgagaaa attaccagaa
     1681 cggtaagaac tatgcgcatg aaggcctgaa aaaatcatat agcactgata ttcatctttg
     1741 gcataacggg aaatgggata aatcgggtga attatcgcaa ggtcgggcct acggagtatc
     1801 attgccctgg aataatagtc tattgattat tggcggtgaa tctgcaggcg gcaaagcggt
     1861 gacggattca gttttgatct ctgtgaagga taataaagtc acagtacaaa actaacgctt
     1921 cagggccccg gtaaagggcc ctgctatcaa tttgtcattt caattacgcg aaaattatat
     1981 gaacgcaata atatcgccca attattacta tgttcttacc gttgctggtc agtctaatgc
     2041 catggcgtat ggcgaaggac tgccattacc ggacagggaa gatgcgcctc atcccagaat
     2101 caaacaatta gcgagattta cgcatacgca tcccggaggc ccgccatgtc actttaacga
     2161 cattattcca ctgactcact gcccacacga tgttcaggat atgcagggtt atcaccatcc
     2221 tctggcaacg aatcatcaaa cacagtacgg caccgttggc caggcactgc atattgcacg
     2281 gaaattactg cccttcattc ctgataatgc agggattctc atcgtcccgt gttgccgtgg
     2341 cggatcggct tttaccgcgg gcagcgaggg gacatattca gaacggcacg gagccagcca
     2401 tgatgcttgt cgttggggaa cggatacccc gctctaccag gatttagtca gcagaacgcg
     2461 agccgcactg gcaaaaaatc cgcataacaa attcctcggc gtatgctgga tgcaaggcga
     2521 atttgactta atgaccagtg actacgcgtc acaccctcaa cactttaatc atatggttga
     2581 agcctttcgt agggatctaa aacaattcca ttctcagctt aataatatta ctgccgcgcc
     2641 gtggttttgc ggcgatacca cctggtactg gaaagaaaat ttccctcatg cgtatgaagc
     2701 tatttatggc aattatcaaa ataatgtttt agccaatatt attttcgtcg acttccagca
     2761 acaaggtgaa agaggactga cgaacgcgcc tgatgaagat ccggacgatt taagcacggg
     2821 atatttcggt tcagcgtacc ggtcagcgga gaactggacg acgtcactgc gaagcagtca
     2881 tttcagcgcg gcagcccgtc gggggattat ttctgacaga tttgtagaag caattttgca
     2941 gttttggcgc gaaaggtgag cggggagttt attcatgggg gatgtccttg tccattccca
     3001 gagcagacaa caaaaaacaa atgagatcaa ggtaatatct cttcacttgc gggctcgaac
     3061 agcaggcaat tgccaatata ataatctggc acaagggtga aaaacgcgca ccgcataaac
     3121 cgttgttatt gcttacagat tagccggatg ccttaataga catccgcgcc ttttcggtta
     3181 tggctcggaa atctacgaac atctacacag tttactggaa cgttttgggc cacagcgttc
     3241 gcagcaccgt cctgatatgc cgttctggcg attataagtc gacggattct ggcaaataga
     3301 cgatgatgat atgcttaatg atgttcaaag aaattaggcc attattatat tattgcttgc
     3361 attttctttc attcctaaaa gcacccgcca ttaatcccag gcgcattatg caaaggaaaa
     3421 tgattaggta aacaataaga tttataatca ggaaaggcga ctcgcaataa aacggaaagt
     3481 cgccttaaca ttggtaaaat atgcccttta ctactcctgt atcatgaacg gctcatcaca
     3541 tttaaagctg acgttgatcc agactaccat atattgcctt tatttcattt tttacgcctt
     3601 cgccacggta caccaaagac gtatcgtatc gttgatactt atcttcccgt gcagcactga
     3661 accagttaaa agatccgaca cacagcagtt cttcatcctc aatcacaatt ttgctgtgga
     3721 cacgattaac caatttcgta gcgataccca tcttattgag cttttcaaca gcatcattca
     3781 gcagatgttg tttctcctga cgcttatcat catcgacatg cgctatattg cagtttttat
     3841 ccgtcaccac ggtaatatca atgccccggg aacgggccaa agccattgat gccagaaatc
     3901 ccgtttgctc cactttttgc caagataacc aaggggaaat aatcgttatt ttcttttgag
     3961 ctccggcaag agtcttgttc aaaaatccat catgctgctc cacaccatgc agcgttgaaa
     4021 tttgtgtatg tgcggaaatt aaat
//
LOCUS       DAPOXO010000191         4007 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.191, whole genome shotgun sequence.
ACCESSION   DAPOXO010000191 DAPOXO010000000
VERSION     DAPOXO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4007
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.191"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            655..984
                     /locus_tag="ROH59_005017"
     CDS             655..984
                     /locus_tag="ROH59_005017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdK family transcriptional regulator"
                     /protein_id="HDX4807379.1"
                     /translation="MAQKNRITEAEWTQLLPHMATLAHITTDIGYSVLVKGEKASDVA
                     ARVGRSKQNISSTAKRIWDLYQNTTLHTEDGEALQLVQVWIPEKLAKKVLAEAAKYSV
                     NKNTVAE"
     gene            997..1218
                     /locus_tag="ROH59_005018"
     CDS             997..1218
                     /locus_tag="ROH59_005018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007372345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807380.1"
                     /translation="MPQGNVIFNKKGKFFWFEDENRIPGLIRSEKEQEWYIAELYYPP
                     EFDYDTAMHDKQIQYLLSKPEELKRYEPK"
     gene            complement(1234..2019)
                     /locus_tag="ROH59_005019"
     CDS             complement(1234..2019)
                     /locus_tag="ROH59_005019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="HDX4807381.1"
                     /translation="MNLPTPETYDELQRAYDFFNEKLFSNELPPCLITLQREKRTYGY
                     CSFKRFVGRESGDTVDEIAMNPVYFSIRTIKATLSTLVHEMVHQWQFHFGEPGRRGYH
                     NKQWAARMERVGLMPSDTGEQGGRKVGQSMTHYIIAGGPFDMACDELLTGHFRLSWMD
                     RFPPYQPKPGAVLSPTGKGYIDDEEDDSEHELEEGRDPVELDDEIIEAMRFVAPPPEA
                     PVNKTNREKYSCPVCHINLWGKPGIVVYCGGEHCEKAQLVVIK"
     gene            complement(2170..3435)
                     /gene="mucB"
                     /locus_tag="ROH59_005020"
     CDS             complement(2170..3435)
                     /gene="mucB"
                     /locus_tag="ROH59_005020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032488541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V subunit
                     MucB"
                     /protein_id="HDX4807382.1"
                     /translation="MIALIDVNGMYASCEQAFRPDLANRAVAVLSNNDGNIVARNYLA
                     KKAGLKMGDPYFKVRPIIERHNIAIFSSNYTLYASMSARFAAVVESHASHVEQYSIDE
                     LFVDCKGITAAMSLDAFGRQLREEVRRHTTLVCGVGIARTKTLAKLCNHAAKTWPATG
                     GVVALDDGARLKKLMSILPVAEVWGVGHRTEKALATMGIKTVLDLARADTRLIRKTFG
                     VVLERTVRELRGEACFSLEENPPAKQQIVVSRSFGQRVEALADMQQAITGFAARAAEK
                     LRNERQYCRVISVFIRTSPYSVRDTQYANQATEKLTVATQDSRTIIQAAQAALARIWR
                     EDIAYAKAGIMLADFSGKEAQLDLFDSATPSAGSEALMAVLDGINRRGKSQLFFAGQG
                     IDNSFAMRRQMLSPDYTTDWRSIPTATIK"
     gene            complement(3432..3863)
                     /gene="mucA"
                     /locus_tag="ROH59_005021"
     CDS             complement(3432..3863)
                     /gene="mucA"
                     /locus_tag="ROH59_005021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_107685442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit MucA"
                     /protein_id="HDX4807383.1"
                     /translation="MKVDIFENSGASQIHSIPFYLQRISAGFPSPAQGYEKQELNLHE
                     YCVRHPSATYFLRVSGSSMEDGRIHDGDVLVVDRSLTASHGSIVVACIHNEFTVKRLL
                     LRPRPCLMPMNKDFPVYYIDPDNESVEIWGVVTHSLIEHPV"
BASE COUNT          998 a         1069 c          941 g          999 t
ORIGIN      
        1 gcaccgtcac ggccagcgcc ccgctgagct gcgcaatcca cggataacac aaagggcaag
       61 ttattcagcg ttaagctgcg cgcgggattc ataaaggtat cctcagacag tccacaggca
      121 tgaagaaaaa tttatccaca ttctgcgctt tctgtgaata accctgttaa ttcagcaagt
      181 tatccaagat aaatcagacc cccccattga gataaatcag accccccaac cgagataaat
      241 cagacccccc aggctgagat aaatcagacc ccctaaacca ggataaatca gaccccccct
      301 aaacctgtaa ggtgatcctg tagttttttc ctttacgatc tcctatacat atatatcctg
      361 taattagccc gctacgggca gtgaataagt cagattccat ctttgcttac cagcgccgct
      421 acgcggctcg gtcaacccct cagaaccgcg aaaacaagtt tcgcagttct tcacggttca
      481 tggtttaatc cgtgcatggc gccagcacct tcgcggcacc atcgaggccc gcgctgctgc
      541 cgcaccgggc ctcacccaaa cataaaatca agtttacaat aatcgtactt gtattgactt
      601 ttagcattta agccgctagt ctctttgtat cagttttatt cggagacaaa tcagatggca
      661 cagaaaaaca gaattaccga agcagaatgg acacagctat tgccacacat ggctacgctc
      721 gcacacatca caaccgatat tggttattct gttttggtta agggtgaaaa agcgtctgat
      781 gtagcagcgc gagtaggccg ttctaaacag aatatttcca gtacagcaaa acgtatctgg
      841 gatctttatc aaaacaccac gttgcatact gaagatgggg aagcccttca gctcgttcag
      901 gtctggattc ctgaaaaact ggctaaaaag gttttagctg aagccgcgaa gtacagtgtt
      961 aataaaaata ctgtcgctga ataacgaggt tatcttatgc cgcaaggaaa tgtcatattc
     1021 aacaagaaag gtaaattctt ctggtttgaa gatgaaaaca gaataccagg attgatacgt
     1081 agtgaaaaag aacaagaatg gtatatcgct gaattgtatt acccacctga atttgattac
     1141 gacaccgcta tgcacgacaa gcaaatacaa tatttgttat caaagcctga agaattgaaa
     1201 cgttacgaac cgaaataaag cccttacggg cttttatttt ataactacca gctgtgcctt
     1261 ttcgcaatgc tcaccgccgc agtaaactac tatacccggc ttaccccaaa gattgatatg
     1321 gcataccggg cagctgtact tttcccggtt agttttattc actggagcct ccggcggggg
     1381 ggcaacaaat cgcatggcct ctatgatctc gtcgtcgagt tcaaccgggt cgcgcccttc
     1441 ttccagttcg tgttcgctat catcttcctc gtcgtcaata tagccttttc ctgtggggct
     1501 tagcacagca ccaggcttag gctggtaagg cggaaacctg tccatccagg aaagccggaa
     1561 atggcctgtc agcagttcat cacaggccat atcgaaaggg ccaccggcaa taatataatg
     1621 ggtcatgctc tggcccactt tcctgcctcc ctgttcgccg gtatctgaag gcattagtcc
     1681 tacccgttcc atccgggccg cccactgttt gttgtgatag ccacggcggc caggctcgcc
     1741 aaaatggaat tgccactgat gaaccatctc atgcaccagt gttgaaagcg tggcctttat
     1801 ggttctgatc gagaaataca ccggattcat agcgatctcg tctaccgtgt ccccactctc
     1861 acggccaacg aaacgcttaa aggaacaata gccatacgtt cgcttctcac gctgcaacgt
     1921 tatcaggcat ggcggcagct cgttgctgaa tagcttctca ttaaaaaaat cgtaggctct
     1981 ctgaagttca tcgtaggttt cgggcgtagg caaattcact gttaacctca catatatgta
     2041 ttgtgcaata cacataattt agctgatctt ttatacagat gaaacgcctt ttaccgaaaa
     2101 ccgcgaaacc gcgccgaaac tcgtttcggc cggttgaggg gttgaccggc ccgcgtgcgg
     2161 cgccggtaat tatttgatgg ttgctgttgg tatcgagcgc cagtctgtcg tgtaatcagg
     2221 tgacaacatc tgacggcgca tggcaaagga gttatcgatg ccctggcctg caaaaaacag
     2281 ctggctcttg ccacgccggt ttatgccatc gagaacagcc attaacgcct cgctgccagc
     2341 tgaaggcgta gcagagtcga ataaatccag ctgggcctcc tttccgctga aatcggccag
     2401 catgatccct gcttttgcat acgcaatatc ttcccgccag atccgcgcca gcgcggcttg
     2461 tgccgcctga attatcgtgc ggctgtcctg ggttgccacc gtcagttttt cggttgcctg
     2521 attggcatac tgtgtatcac gcactgaata aggactggtg cggataaaga cgcttatgac
     2581 gcggcagtat tgccgctcat tacgcagttt ttcagctgcg cgcgctgcaa atccggtgat
     2641 cgcctgctgc atatccgcca gggcttctac gcgttggccg aatgagcgcg acacaacaat
     2701 ctgctgcttc gcaggagggt tttcttccag gctgaagcaa gcctcgccgc gcagctcccg
     2761 taccgttctt tcaagcacaa cgccgaacgt tttacggatt agccgcgtat ctgccctagc
     2821 taaatccagc accgttttga tccccattgt ggcgagtgct ttctctgtac gatggccgac
     2881 gccccagact tccgcaaccg gcaggatgct cattaatttt ttcagtctgg cgccatcatc
     2941 cagagcaacc accccgccag ttgcgggcca tgtttttgcc gcgtggttac acagtttcgc
     3001 cagcgtctta gtgcgggcaa taccgacccc gcataccagc gtggtgtgtc gcctgacttc
     3061 ctcgcgcagc tggcgcccga aagcgtcaag actcatggcg gccgttatcc ctttgcagtc
     3121 aacaaaaagc tcgtcgattg aatactgttc gacgtggctt gcatgggact caactacggc
     3181 cgcgaaccgg gccgacatgg aggcatagag agtgtaatta gaactaaaaa tagcgatgtt
     3241 gtgacgctca attatgggtc tgactttgaa gtacggatcg cccattttca ggcccgcttt
     3301 cttcgccagg taattacggg ccacaatgtt gccgtcgttg ttggataaaa cggccaccgc
     3361 tcggtttgcc agatcgggcc taaatgcctg ctcacagctg gcgtacatgc catttacatc
     3421 aatcagcgca atcataccgg atgctcgata agggaatgcg taaccacacc ccagatttca
     3481 acgctctcat tatccgggtc aatgtagtag acaggaaaat ctttgttcat cggcatcagg
     3541 cagggtctgg gcctcagcaa tagccgcttc acggtaaatt cattatggat gcaggcgact
     3601 acgattgagc cgtggctggc cgtcagcgag cgatccacaa ccagtacgtc accatcatgg
     3661 atgcggccat cttccatcga cgagccagaa acccgcagga agtaagttgc tgaagggtga
     3721 cgaacacaat actcatgcag atttaactcc tgcttttcat agccctgggc cgggctgggg
     3781 aaccccgcag aaattctttg cagataaaac gggatgctgt gtatctggct ggcgccggaa
     3841 ttttcaaaaa tatcgacctt catagcgatc ttccaaatca ctgtttattt atacagtatc
     3901 gctgttatgg tcaggttggc aagttttacc gctacgctac tatatgtagt gctgtttcag
     3961 ctgccggcga acgctatata tagtgtttgt tggctttctg cttgctc
//
LOCUS       DAPOXO010000192         3984 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.192, whole genome shotgun sequence.
ACCESSION   DAPOXO010000192 DAPOXO010000000
VERSION     DAPOXO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3984
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.192"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..137)
                     /locus_tag="ROH59_005022"
     CDS             complement(<1..137)
                     /locus_tag="ROH59_005022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX4807384.1"
                     /translation="MMMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFL
                     E"
     gene            complement(134..1156)
                     /gene="istA"
                     /locus_tag="ROH59_005023"
     CDS             complement(134..1156)
                     /gene="istA"
                     /locus_tag="ROH59_005023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="HDX4807385.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEP
                     PKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRGFIR
                     SLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMR
                     YDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFS
                     PRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVA
                     NQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHPGENLVNFDKHPLHHPLSIYDS
                     FCRGVA"
     gene            1245..1355
                     /locus_tag="ROH59_005024"
                     /pseudo
     CDS             1245..1355
                     /locus_tag="ROH59_005024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            1399..1554
                     /locus_tag="ROH59_005025"
                     /pseudo
     CDS             1399..1554
                     /locus_tag="ROH59_005025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            2681..3826
                     /locus_tag="ROH59_005026"
     CDS             2681..3826
                     /locus_tag="ROH59_005026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001388349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807386.1"
                     /translation="MGKELDDICTSCPYIDAVKRHKQQLGAIEEYTKWLKKEPRASYF
                     FLFRLYTRIHNTFFPQKQQLPFTPGGTHCPEPDVTLRDLTLSPGYHSDYAPHPIPEMD
                     SSIVVPPTNENTSPPEDTPDNTPAGGNTGQAEKTRNAGLTPIPEKRSGMPPEHLRFAM
                     GFPSQPKIAGPREKPMRTVHPDNIYREIIWFCSSYLLKSGPEATRTIINSVFSEWASI
                     NNDYPSPFSWVDSRDSEQCDWLWNAMQVRCVGTPLNPLTPEQKYWFACATFDNWEGWN
                     EQQVQFLLESNPRRNRAKFTQASFQAPRIQHKAILLDELKSAREQQKRRDERADGSVP
                     LKLSGKIHKQLESIARSRGVLPKKLLNEMIEQAYQDFVANEQHKTLS"
BASE COUNT         1086 a          985 c          997 g          916 t
ORIGIN      
        1 tgctccagga agtccatata actccattcc tggtctactg cctgttgtga cagcgcaggc
       61 gctgcgctta taaggctttc cagttgcaac tgcccggcga gcgccatcag tcgttgatgt
      121 tgcagttcca tcatcacgcc actcctctgc agaatgagtc gtagatggag agtggatgat
      181 gcagggggtg tttgtcgaag ttcaccagat tttcaccagg atgcacgtca tactcttttt
      241 tctccggagg cagtgccagc atggactgct gctcttcgag ccagcgatcg cagggacggg
      301 cctggattgt ttcatgcttt cgttggttag cgacatcgtg cagccagcgc agaccgtggc
      361 ggttggctgt ttcaacatcg acagtgatcc ccatcgggcg caggcgagtc attagtggga
      421 tgtaaaaact gttacgggtg tactgcacca tccgttccac cttaccttta gtctgtgccc
      481 tgaaggggcg acacagtcgg ggagagaagc ccatctcctt gccgaactgc cacagcgaag
      541 gatggaaccg gtgctgaccg gtctgatatg cgtcacgttg cagaaccaca gttttcatat
      601 tgtcatacaa cacttcgcgc ggcacaccac caaagaagcg gaacgcatta cgatggcagg
      661 tttccagcgt gtcataacgc atattgtcag tgaattcgat gtacaacatt cggctgtatc
      721 cgagaacagc aacgaacacg tgaagcggtg agcggccatt acgcatagtg ccccagtcaa
      781 cctgcatctg tcgtccgggt tcagtttcga accgaacggc aggctcctgc tcctgaggaa
      841 ccgagagaga acgaatgaat cccctgagaa tggtcattcc gccacgatat ccctggtctc
      901 tgatctcgcg agcgattacc gttgccggga ttttgtaagg atgagcatcg gcgatgcgtt
      961 gacgaatata atcccggtat tcatccagga gtgaagcaac agcaggtcgc ggcgtatatt
     1021 ttggcggctc agattttgcc tgcaaataac gtttaaccgt attgcgggag atccccagtt
     1081 ctctggcaat cgcccggcta ctcattccct gcttgtgcag gattttaatt tccataactg
     1141 tctcaaaagt gaccataagc tctcctgaat caggagagca gattaccccc tggatctgat
     1201 ttcaggcgtt gggtgtggat cactattgca ccgttcgtga cacaatgggc catacgggcc
     1261 gacgttccat gccgcgttac tacattcagc ccggacgtaa aatgcgcccg tcaaaaagaa
     1321 cggttcgctt cgaaactcag ccaggatacc acctctccgc cacacccggg aagaagttga
     1381 tatggtggtt gccggacaac agagctcttg gattgactgc tgcatcactc aaccacgctg
     1441 aatatcaaag gagagcgtta ccggttaaaa gagaaacgta aagctgtggt gatgacccaa
     1501 aacgcaacgc ctgtcagtga ggatgaaatg gtgaaaagcg gacagcatca gtaacggaag
     1561 tatcttagcg ggtacgaaaa tggcaggatc gtgacattga cagaatatct cctgatcatc
     1621 ctgaatgact gcagttgctg tggaaaagta agctgtctcc acccacggca cgacttaaca
     1681 ggcattccgt aactccccca gacttactat gacgcattat cggtgcactt aaaaccgcag
     1741 accgcattgc gggtgttact gcatgacagt ctgaccgtat tgtgagatgt cggcaggaac
     1801 cgatgtccgc gcagggggga acttcctgca gtacctgacg cttcaaatag tattaaccgt
     1861 agggcgttgt tggttccgga tcgcggaaat gggagcacag gtctgctacg gggtgtacct
     1921 ctgacagtaa atccggctcg ctcatctgac agcctctctc ccggaaaaga ccaaaaatga
     1981 gatcgtctcc tcaacagcag agaagaggtc ttgacagaca ggctacattg catacgattt
     2041 atgaagaaaa agacagcaaa tatggaggtt atagcggaga acaccctacg aaattcctat
     2101 gaaaaacgat tgaaaaaaat atcaaattcg attcgttttt atatgctttt tgggaacgtg
     2161 gcgatgacga actgttgcat gtgcagagga gaatgcaccc ggaagcacca gaatcatcca
     2221 gaaaggcaga acgattacgc atcaaaccag gagacagcaa tatcaaggta atacactgat
     2281 ttaaaatgaa tttacagcaa tacgtgaaaa cattttttac ttaaaggaga cagatgcgct
     2341 gaagagagtg caggtatttt tatataaaaa tgagaagatt acgggatata tatccggcac
     2401 actatgaccg gagaatacca gtcaggctta aaaagacaat aaatacagtg agttaaatac
     2461 acagagaaaa cgaaaacgta gtatcagagg gtacatctta caacagagac tgaatttccg
     2521 gtttttcata accggcgcat tccggaaaat gcaggcggcc cggagctctt ctgacgccag
     2581 tacctgatag attgttctgt acattctgta catcatgtac ggaggttttt gtttgctttc
     2641 ttaaaatctg caaatgtggg aagagcaggt gaggtgtatt gtgggaaagg aactggatga
     2701 tatctgcacc agctgtccgt atatcgatgc tgtaaaacgg cacaaacaac agctcggtgc
     2761 catagaggaa tatacaaagt ggttaaaaaa agaaccacgg gcatcttatt tttttctgtt
     2821 ccggctgtat acccgcattc acaatacatt tttcccccaa aagcaacaac tcccgttcac
     2881 tcccggtggc actcactgcc cggaacctga tgtcaccctt cgggacttaa cgctttcccc
     2941 gggctaccac agtgattatg cccctcaccc cattccggag atggacagtt ctattgttgt
     3001 tccccccact aatgaaaaca cctcgcctcc ggaagatact cccgacaaca ctccggccgg
     3061 aggcaatacc ggacaagcgg aaaagaccag aaacgcagga ctcacaccca ttcctgaaaa
     3121 acgttcagga atgcccccgg aacatctgcg gtttgccatg ggttttccat cgcaaccgaa
     3181 gattgccggt cccagagaaa agccgatgcg caccgtgcat ccggataata tctaccgtga
     3241 aattatatgg ttctgctcca gttacctgct gaaatccgga ccagaggcta cgaggacgat
     3301 tatcaactca gtattctctg aatgggccag cataaacaat gattacccct cccccttttc
     3361 gtgggtggac agcagggaca gtgaacagtg tgactggtta tggaacgcca tgcaggtccg
     3421 gtgtgtggga accccgctga atccccttac cccggagcag aaatactggt tcgcctgcgc
     3481 cacgtttgat aactgggaag gctggaatga gcaacaggta cagtttttac tggaaagtaa
     3541 tcccagacgg aacagagcga agtttacgca ggcctccttc caggccccca ggattcagca
     3601 taaagcgatt cttcttgatg agctgaaaag tgcccgggag caacaaaaaa ggcgtgatga
     3661 acgtgctgat ggttccgtcc cgctgaaact gtccggaaaa atccacaaac agcttgaaag
     3721 tattgcccga agtcgtggtg tcctcccaaa aaaactgctg aatgaaatga ttgagcaggc
     3781 gtaccaggac tttgtggcaa atgagcaaca caagacactg agttaaggac cgcagggcct
     3841 ccggttaccg attctgcagc atacacaacg aatgtgtccg gctcttacct gtgggggccg
     3901 cactaaagtt acgcattgag tatgagtggg taatcccgga tgagaatatc ccagttttta
     3961 cactattcac tgaaggtgcg acat
//
LOCUS       DAPOXO010000193         3908 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.193, whole genome shotgun sequence.
ACCESSION   DAPOXO010000193 DAPOXO010000000
VERSION     DAPOXO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3908
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.193"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..261)
                     /gene="ihfA"
                     /locus_tag="ROH59_005027"
     CDS             complement(<1..261)
                     /gene="ihfA"
                     /locus_tag="ROH59_005027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HDX4807387.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKL"
     gene            complement(266..2653)
                     /gene="pheT"
                     /locus_tag="ROH59_005028"
     CDS             complement(266..2653)
                     /gene="pheT"
                     /locus_tag="ROH59_005028"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDX4807388.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHNGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVEPEIVPVGATIDDTLPIAVEAPDACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGIHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            complement(2668..3651)
                     /gene="pheS"
                     /locus_tag="ROH59_005029"
     CDS             complement(2668..3651)
                     /gene="pheS"
                     /locus_tag="ROH59_005029"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDX4807389.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
BASE COUNT          882 a         1121 c          968 g          937 t
ORIGIN      
        1 taacttctgc ccgggtctga aggtcaccac gcgccgtgct gtaatgggaa tatcctcgcc
       61 cgttttcggg ttacgtcccg ggcgttgatt cttatcacgc agatcgaagt taccaaaacc
      121 agagagtttc acctgttcgc cgttttccag agcgcgacgg atctcttcga aaaacagttc
      181 aaccagttct ttggcatccc gcttgctaag cccaagctta tcaaacagat attctgacat
      241 ttcagctttt gtaagcgcca taggttcaat ccctcaatga tgcctggaat cgctctttta
      301 atgcctctac acatttggcg acggtagcgg caatctcctc ttcttcgagt gtacggctgg
      361 tatcttgcag gatcaggctt atggcgaggc tcttataccc ctccgcaaca cccttaccgc
      421 ggtacacgtc aaataagttt acgccaacta cctgatttac gccaactttc ttacattcgg
      481 ataaaatatc cgctgcggga acgttttctg cgaccaccac cgcgatgtca cgacggttcg
      541 ccgggaagcg agaaatctcg cgcgcctgag gcaccacgcg gtctgcgagc ttgttccact
      601 ccagttcgaa caccagagtg cgaccgttaa gatccagttt acgttccagt tcaggatgaa
      661 caaccccaac aaaaccaata cgttcacctt tcagataaat cgctgcggat tgccccggat
      721 gcagtgccgg attcgcttct gcacggaact caacctcatt cagtttaccg gtcaggtcga
      781 gaacggattc aagatcgcct ttcaaatcat agaaatcaac ggtctctttt gccaggttcc
      841 agtgctcttc gtaacggtta ccgcaaatca caccggctaa catcagatcc tgacgaatac
      901 ccaacggtgc ctgagtatct ggcacgaaac gcagaccgct ttcgaaaatg cgtacacgat
      961 tctgctgacg gttctggttg tacaccacgg ttgccagcag gccggtccac agagaaagac
     1021 gcattgctga catttcaaca gagatcgggc ttggcagcag taaggcttca acgcctggat
     1081 ggatcatctg ctgcactttc ggatcaacga agctgtaggt gatcacttcc tgatagcctt
     1141 tgtcgttgag cagcgttttt acgcgcttga gcgacaggtc agcttcacgg tgaatcccca
     1201 taatcaggct tgcctgtacc ggctcatccg ggatgttgtt gtagccgtaa acacgcgcga
     1261 cttcttcgac cagatcttct tcaatctcca tgtcgaaacg ccagctcggc gcaactgcct
     1321 gccactcgtc tttgccttcg gtcacttcgc agccgagacg acgcagaatg tctgttacct
     1381 gctcatcagc aatatgatgg ccgatcaggc gatccagttt gctacgacgt aaagtgatgg
     1441 ttgcacgctt cggcagcgtt gcttcgttag tgatatcaat taccggaccc gcttcaccac
     1501 cgcagatgtc gatcagcaga cgggtcgcac gttccatcgc tttgtgctgc agtgccggat
     1561 caacgccacg ctcataacgg tgagacgcat cagtatgcag gccatgacga cgagcacgac
     1621 cggtgataga cagcgggctg aagaaagcgc attccagcag aacgttttgc gtttcgtcat
     1681 tcacgccaga gtgttcgcca ccaaatatgc cgcccatcgc cagcgccttg ttgtggtcgg
     1741 cgatgaccag ggtgtcagca ttcagcttcg cttcagtacc gtcgagcaat accagcgttt
     1801 caccctcttt tgccatccgc accacaatgc cgccttcaat gcgatcttta tcgaaagcgt
     1861 gcatcggctg gcccagttcg agcagcacat agttggtgac gtcaacaact gcatcgatag
     1921 aacggatccc gcaacgacgc agtttttctt tcatccacag cggagttggc gctttaacgt
     1981 taatgccttt tacaacacgg ccaagatagc gcgggcaggc atccggcgct tctactgcaa
     2041 tcggcagcgt gtcgtcgatg gtcgcaccaa ccggaacgat ttccggttca accagcggca
     2101 gctggttcaa cacggcaacg tcgcgcgcaa caccaatgat acctaagcag tcggcacggt
     2161 ttggtgtcac gctgatttcg atggtgttgt catcgagttt caggtattcg cggatgtcgg
     2221 tgccaatcgg cgcatccgca ggcagctcga taatgccgtt atgatcgtca gaaattccca
     2281 gctcagagaa ggagcacagc atcccttcag acggttcgcc acgcagtttc gcggctttaa
     2341 ttttgaaatc acccggcaga acagcaccaa tggtcgctac cgccacacgc aggccctgac
     2401 ggcagtttgg cgcaccgcag acgatgtcca gcaggcgatc gccgccgaca ttcacttttg
     2461 tcacacgcag tttgtcagcg ttcggatgct gcgcacactc aaccacttca cccacaacca
     2521 cgccgtggaa gctaccggca accggttcta caccatcaac ttccaggccc gccatcgtga
     2581 tttgatttgc cagcgcgtcg ctatcaatcg ccgggttcac ccattcgcgt aaccacagtt
     2641 cactgaattt cataatctat tcctgcctta tttaaactgt ttgaggaaac gcagatcgtt
     2701 ttcaaagaat gaacgcaggt cggtgacgcc gtagcgcaac atagtcagac gctccatccc
     2761 catcccgaag gcgaaaccag agtaaacttc cgggtcgatg ccaacgttac gcagcacgtt
     2821 cggatgcacc atcccgcagc ccagtacttc cagccatttt ccgtttttac ccatgacgtc
     2881 cacttctgca gaaggttcgg taaacgggaa gtaggaagga cggaagcgga tctgcaaatc
     2941 ttcctcaaag aagttacgca ggaagtcgtg cagcgtgcct ttcaggttag taaagctgat
     3001 gttggtatca acaatcagac cttccatctg atggaacatc ggcgtgtgag tctggtcgta
     3061 gtcgttacga taaacgcggc caggcgcgat gatacgaatc ggtggctgct gggctttcat
     3121 ggtgcggatc tgtacgccag aggtctgggt acgcagcagg cgggtagcgt caaaccagaa
     3181 agtgtcgtgg tcagcgcgcg cagggtggtg accaggaatg ttcagagcat cgaagttatg
     3241 ataatcgtct tcgatttccg gcccggttgc cacggtaaag ccaagctcac cgaagaaact
     3301 ttcgatacgg tcgatggtac gggtaaccgg atgcagcccg ccgttttcaa tgcgacgacc
     3361 aggcagggag acatcaatcg tttccgccgc cagacgcgca ttcagtgctg cgctttccag
     3421 ttccgcttta cgcgcattca gcgcctgctg aacctgctct ttcgcttcat tgataaccgc
     3481 accagctgcc ggacgctctt ctggcggcag ctcacgcagg gtcgtcatct gaagggttaa
     3541 gtgccctttt ttacccaaat attcgacgcg cacattatct aacgcggcaa catctgacgc
     3601 ctggctaatg gccgccttcg cactggcaac cagttctgcg agatgtgaca tgtttttcct
     3661 cattgtgtca gtggtgacac tggttcgttg gacttagagc ccatcccatc aggctatttt
     3721 acttgccatt ttggtcccgg gcagtgctcg aaatcctcac gtacttaagt acggtccggt
     3781 ttctccgcgc tggccgtgtc cagactggct gcgacaatta cgcctgatga gacaggcttt
     3841 ttatttttca aaacgcgcat acaaaaaaag cctccactgg gaggctttca ggcgctgttt
     3901 tccgtttc
//
LOCUS       DAPOXO010000194         3722 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.194, whole genome shotgun sequence.
ACCESSION   DAPOXO010000194 DAPOXO010000000
VERSION     DAPOXO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3722
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.194"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..201)
                     /locus_tag="ROH59_005030"
     CDS             complement(<1..201)
                     /locus_tag="ROH59_005030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HDX4807390.1"
                     /translation="MQNLNPQRKAFLDMLAWSEGTDNGRQPTRNHGYDVIVGGELFTD
                     YSDHPRKLVTLHPKLKSTAAGRY"
     gene            complement(188..493)
                     /locus_tag="ROH59_005031"
     CDS             complement(188..493)
                     /locus_tag="ROH59_005031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDX4807391.1"
                     /translation="MHEKESLAGAFWLVLLIIAGWGGLVRYLIDVKQSKATWSWINAL
                     AQIVVSGFTGVIGGLISIESGFSIYMILATAGISGAMGSVALTYFWERLTGVKNAKS"
     gene            complement(815..1504)
                     /locus_tag="ROH59_005032"
     CDS             complement(815..1504)
                     /locus_tag="ROH59_005032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDX4807392.1"
                     /translation="MNTQYLQYVREQLIVATADLSGATKGQLEAWLEHAQFDTGTYKR
                     KKPRILDEVTGRMITLDNPPISGKQLYAKGSSIALVSQVEFSTSSWRRAVLSLEEHQK
                     AWLLWSYSESVRWEHQVTITQWAWSEFKTLLGTRKIAGKTLERLKKLIWLAAQDVKNE
                     LAGRKTYEYQELASLVGVTSKNWSETFTERWVAMKHIFLQLDSQALLLLTKTRSKQKT
                     IFSQQDIAKLD"
     gene            complement(1501..1641)
                     /locus_tag="ROH59_005033"
     CDS             complement(1501..1641)
                     /locus_tag="ROH59_005033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HDX4807393.1"
                     /translation="MMFESYMAERLRRRWVRLRLYRFPSSVLTDYRILKNYAKTLKGA
                     AA"
     gene            complement(1638..2000)
                     /locus_tag="ROH59_005034"
     CDS             complement(1638..2000)
                     /locus_tag="ROH59_005034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDX4807394.1"
                     /translation="MNTYCITLPWPPSNNRYYRHNRGRTHISAEGQAYRDNVARIIKN
                     AMLDIGLAIPVKISIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKM
                     PVTKGGKLELTITELGDE"
     gene            complement(1997..2287)
                     /locus_tag="ROH59_005035"
     CDS             complement(1997..2287)
                     /locus_tag="ROH59_005035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HDX4807395.1"
                     /translation="MADLRKAARGRECQVRIPGVCNGNPETSVLAHIRLAGLCGTGIK
                     PPDLIATIACSACHDEIDRRTHFVDAGYAKECALEGMARTQVIWLKEGVIKA"
     gene            complement(2280..2450)
                     /locus_tag="ROH59_005036"
     CDS             complement(2280..2450)
                     /locus_tag="ROH59_005036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807396.1"
                     /translation="MATPLIRVMNGHIYRVPNRRKRKPELKPSEIPTLLGYTASLVDK
                     KWLRLAARRNHG"
     gene            complement(2450..2905)
                     /gene="ybcN"
                     /locus_tag="ROH59_005037"
     CDS             complement(2450..2905)
                     /gene="ybcN"
                     /locus_tag="ROH59_005037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA base-flipping protein YbcN"
                     /protein_id="HDX4807397.1"
                     /translation="MNLPQDGIKLHRGNFIAIGQQIQPYLENGKCFRMVLKPWREKRS
                     LSQNALSHMWYSEISEYLISRGKSFATAAWVKDALKHTYLGYETKDLVDVVTGEITTI
                     QSLRHTSDLDTGEMYVFLCKVEAWAVNIGCHLTIPQSCEFQLLRDKQEA"
     gene            complement(2902..3003)
                     /locus_tag="ROH59_005038"
     CDS             complement(2902..3003)
                     /locus_tag="ROH59_005038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807398.1"
                     /translation="MRTHNPNSLLPSQMQKCTCVFLHLASDLCGGEA"
     gene            3353..>3722
                     /locus_tag="ROH59_005039"
     CDS             3353..>3722
                     /locus_tag="ROH59_005039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4807399.1"
                     /translation="MKINKILSSATLLYGMSMAMSVGSCATPVQTNLPGYTPGADIIS
                     VSPTRNQVDLIGDVVYSQIKGTRSVRQLHMSVLVPRTNDLKPAIIYYPGGGFMSSEHD
                     KFIEMRMALAEAGFVVAAVEY"
BASE COUNT          951 a          926 c          852 g          993 t
ORIGIN      
        1 ataacgtccg gcggctgttg atttgagttt ggggtgtagc gtgacaagtt tgcgagggtg
       61 atcggagtaa tcagtaaaca gttcgccgcc aacaataaca tcataaccgt ggttacgtgt
      121 cggttgtcgc ccgttatccg ttccttctga ccacgccaac atatcgagga aggctttacg
      181 ctgaggatta agattttgca tttttcaccc ctgtcagtcg ttcccagaag tacgtcagtg
      241 caaccgaacc catcgcacca ctaatccccg ctgtcgcgag aatcatgtaa atactgaatc
      301 cactttcgat gctgatcagg ccaccaataa caccggtgaa tcctgatacc actatttgag
      361 ccagagcatt tatccaactc cacgttgctt tactctgctt cacatctatc aggtagcgga
      421 ccagaccgcc ccaacctgcg atgatcagca aaacgagcca gaacgctccg gcaaggctct
      481 ctttttcgtg catatgaata gccaatgttt cgccgccgac aaaaggccgg gacgttaaat
      541 gtcagaaatc aggctcacgg ggtaatttaa cgacaaagca cggagttgat gctccccgca
      601 agcctggaat aaaaaagcca gcatgtagct ggcaacagag ggttaagcaa tatcaactca
      661 acagctgaag acaccctggc tggggtaggt tggaaggcta ctcaccgttc agaaacagaa
      721 aagcccaagg ctttaaacct cgggcttgaa tttggattac tgccagtgcg tacaacattg
      781 gcaaaatatc agatttacat aaaatatatg atttttaatc cagttttgca atatcttgct
      841 gtgaaaatat ggtcttttgt tttgaacgtg ttttcgttaa aagcaataaa gcttggctat
      901 caagctgtag aaaaatgtgc ttcattgcaa cccagcgttc agtaaatgtc tcagaccagt
      961 tttttgatgt cactcccacc agtgatgcca gctcctggta ttcataggtc ttacgccctg
     1021 ccagctcgtt cttcacatcc tgtgccgcca gccagatcaa cttcttcaaa cgttccagtg
     1081 ttttacctgc aattttcctg gtacccaaca gagtcttaaa ctcgctccat gcccactgcg
     1141 ttatggtgac ctgatgttcc cagcgaacac tttcgctgta actccacagc aaccacgctt
     1201 tctgatgttc ttcgagagac agaaccgcgc ggcgccatga cgaggttgag aactcaacct
     1261 ggctgaccag tgcaatggat gaaccttttg cgtacaactg cttaccggaa atcggcggat
     1321 tatccagcgt aatcatcctg ccagttacct catccagaat gcgcggcttc tttcgtttgt
     1381 atgtaccagt atcaaattgt gcatgctcca gccaggcttc aagctgtcct ttcgttgctc
     1441 cgctcaaatc agcggtagcc acaatgagtt gctcgcggac atactgtaaa tattgggtat
     1501 tcatgcggca gctcctttca gtgttttggc gtaattcttc agtatccggt aatcggtcaa
     1561 aacagaacta ggaaaacgat ataagcgcag gcgcacccag cggcggcgaa gacgttctgc
     1621 catataagac tcaaacatca ttcatctccc agttcagtga tagtcagctc cagcttccca
     1681 cctttggtaa cgggcatctt cacaacgcgg taatcaacga cctgagcatc atccagccag
     1741 aaacctgctt tggtgagtgc gtcaaaagcg gccttttgca gattatcaag gtcacggcga
     1801 cggcgatccg gcatgtggca ctcaatgctg attttcacag gaatagccag gccgatatcc
     1861 agcattgcgt ttttaatgat tcgggcgaca ttatcgcggt atgcctgccc ctctgcgctg
     1921 atatgcgtgc gtccgcgatt atggcggtaa tagcgattat tgctcggcgg ccagggtagt
     1981 gtgatgcagt aagtattcac gccttaatta ccccctcttt cagccagata acctgtgttc
     2041 tcgccatacc ttccagcgca cattcttttg catatccagc gtcaacaaaa tgcgtgcgac
     2101 ggtcgatttc gtcgtggcag gcagaacatg caatggtggc aatcaggtct ggcggtttga
     2161 taccggtacc gcacaatcca gccagccgga tatgtgccag tactgacgtt tcaggattgc
     2221 cattacatac gccagggatt cttacctggc attcccgacc acgcgctgct tttctcaagt
     2281 cagccatgat tcctccttgc tgccagtcgc aaccattttt tatcaaccag gctggcggta
     2341 tatccgagca gtgttggtat ttcggatggt ttcagctcag gcttacgctt acgacgattt
     2401 ggtactctgt agatgtgtcc gttcatgaca cgaataagcg gtgtagccat tacgcctcct
     2461 gcttgtcgcg cagcagctgg aactcgcagc tctgcggaat agtcaggtgg cagccaatat
     2521 tcaccgccca ggcttcaacc ttacacagga agacatacat ctctccggta tcgagatcgg
     2581 aggtatggcg taacgactgg atagtagtga tttcgccggt tacgacatca accaggtcct
     2641 tggtttcata accgaggtat gtgtgtttga gagcatcttt tacccatgct gcggtagcga
     2701 acgatttccc cctgctgatg aggtattcac tgatttcgct gtaccacatg tggctgagtg
     2761 cattctggga aagactgcgt ttctcacgcc acggtttaag caccatgcga aagcattttc
     2821 cgttctccag ataaggctgg atctgctggc cgatagcgat gaagttaccg cgatgcagtt
     2881 tgatgccatc ttgtggtagg ttcacgcttc acctccacag aggtcagacg ctagatgcaa
     2941 aaaaacgcag gtgcatttct gcatctgtga agggagaaga gagtttggat tgtgtgtgcg
     3001 cataaacgtc cccgtttagc gcagaagtca ccggagttgt tcaggctccg gtgatacaat
     3061 tatggcgaat tgattattca taatcaaaca agataaggtc tcaaacttca tgcaagccaa
     3121 gatttatttc tgacagaatt atacaaagaa gctattggtc agaatctact cggactgtaa
     3181 aacatacgca taaccttaag ctctcacttt aagcattgtt gaaataatag ccgtcaagta
     3241 caaccttaac cacgactggg atatttccct ggctaccacg agttgtacgg ctattaaact
     3301 gccgttaaat ttagtaagag aatttcatcc gataagtcaa ggcatgtaaa acatgaaaat
     3361 taacaagata ttatcatctg caacactatt gtatggtatg tcaatggcca tgtcggtcgg
     3421 gagttgtgca acacctgtcc agactaatct tcctggttac accccgggtg cagatatcat
     3481 tagtgtttca ccgaccagaa accaggtcga tctcattggt gatgttgttt attcccagat
     3541 aaaaggaact cgttctgtca gacagcttca catgtcagtt cttgtcccgc gaacaaatga
     3601 tttaaaacca gccattattt attatcccgg cggcggattc atgtcttctg aacatgacaa
     3661 atttattgaa atgagaatgg ctctggcaga agctggtttt gttgtggccg ctgtagaata
     3721 ca
//
LOCUS       DAPOXO010000195         3581 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.195, whole genome shotgun sequence.
ACCESSION   DAPOXO010000195 DAPOXO010000000
VERSION     DAPOXO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3581
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.195"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            1..182
                     /gene="fimB"
                     /locus_tag="ROH59_005040"
                     /pseudo
     CDS             1..182
                     /gene="fimB"
                     /locus_tag="ROH59_005040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313298.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimB"
     gene            complement(213..1433)
                     /locus_tag="ROH59_005041"
     CDS             complement(213..1433)
                     /locus_tag="ROH59_005041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEc53 family transposase"
                     /protein_id="HDX4807400.1"
                     /translation="MDEKSLYAHILNLTAPWQVKSLTLDENAGSVTVTVGIAENTQLT
                     CPTCRKSCSVHDHRHRKWRHLDTCQFMTLVEADVPRVMCPEHGCQTLPVPWAGSGSRY
                     TLLFESFVLSWLKISTVDAVRKQLKLSWNAVDGIMTRAVKRGLSRIKKPLSVRHMNVD
                     EVAFKKGHRYITVVSDRDGRALALTDDRGTESLASYLRSLTDSQLLAIKTLSMDMNAG
                     YIRAARIHLPNAVEKIAFDRFHVAKQLGEVVDKTRQNEHPHLPVESRRQAKGTRFLWQ
                     YSDKWMTESRQEKLMWLREQMQQTSQCWTLKELAKNIWDRPWSTERRNDWLQWISLAS
                     ECDVPMMKNAAKTIKKRLYGILNAMRHRVSNGNAEALNSKIRLLRIKARGYRNRERFK
                     LGVMFHYGKLNMAY"
     gene            complement(1452..1970)
                     /locus_tag="ROH59_005042"
     CDS             complement(1452..1970)
                     /locus_tag="ROH59_005042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HDX4807401.1"
                     /translation="MSVPQTKAELLLAIDKNFSKLISYLNTIPPEITSDKSMDGHAKG
                     TEMSVRDLVSYLLGWNALVVKWIASDAKGLPVDFPETGYKWNQLGLLAQKFYSDYSEL
                     SYELLVAELQTVKNEIVNLINDRTDDILYGRPWYTKWTMGRMISFNTSSPYANANGRL
                     RKWAKNNNISLK"
     gene            2070..2477
                     /gene="fimB"
                     /locus_tag="ROH59_005043"
                     /pseudo
     CDS             2070..2477
                     /gene="fimB"
                     /locus_tag="ROH59_005043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313298.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimB"
     gene            2955..3551
                     /gene="fimE"
                     /locus_tag="ROH59_005044"
     CDS             2955..3551
                     /gene="fimE"
                     /locus_tag="ROH59_005044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418733.1"
                     /note="upgraded from regulatory protein to switch DNA
                     invertase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimE"
                     /protein_id="HDX4807402.1"
                     /translation="MSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISE
                     LLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDEREAVERWTQERANWKGADRTDAI
                     FISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL
                     GHRNIRHTVRYTASNAARFAGLWERNNLINEKLKREEV"
BASE COUNT          961 a          776 c          767 g         1077 t
ORIGIN      
        1 ataacaaaaa aaggaacttc ctgacccata gtgaaatcga atcactcctt aaagcagcaa
       61 ataccgggcc tcatgcagca cgtaattatt gtctgacttt gctttgtttt attcatggtt
      121 tccgggcgag tgaaatttgt cgattgagga tttcggatat tgatcttaag gcaaagtgta
      181 tatagggtct tccccgatca tggtgggaag actcagtacg ccatattcag tttcccatag
      241 tggaacataa ctcccagttt aaagcgttcc cggtttcggt atcccctggc ctttatcctc
      301 agcagtctga tcttgctgtt cagcgcctcc gcatttccat tcgagacgcg atgacgcatt
      361 gcattcagta ttccgtataa ccgtttttta atggttttcg ctgcgttttt catcatcggc
      421 acatcacatt cagacgccag cgatatccac tgcaaccagt cattcctgcg ttctgtgctc
      481 caggggcgat cccagatatt ttttgccagc tctttcagtg tccagcactg gcttgtctgt
      541 tgcatctgtt cccgcaacca catcagcttt tcctgccggg actcagtcat ccatttgtcg
      601 ctgtactgcc acaggaagcg ggtacctttg gcctgacgac gactttcaac agggaggtgc
      661 ggatgttcat tctggcgggt tttatcaacc acttcgccca gttgcttcgc cacatggaag
      721 cgatcgaagg cgattttctc gaccgcattg ggtaaatgga tacgcgctgc tcttatatag
      781 cccgcattca tgtccatcga cagtgttttg atggccaaca actgactgtc agtaagcgaa
      841 cggagatagc tggcaagact ctctgtgcca cgatcatcgg ttaatgccag tgcccgcccg
      901 tcgcgatcag ataccacggt tatataccta tgcccttttt taaaggcgac ttcgtctaca
      961 ttcatatgac gcactgataa aggcttttta atccgcgaca ggcctcgctt aaccgcgcgg
     1021 gtcatgatgc cgtcaacggc attccagcta agtttaagtt gttttctgac cgcatcaacg
     1081 gtgctgattt taagccatga gagcacgaac gattcgaaca gcagagtgta ccgactgccg
     1141 gaacctgccc acggtacagg cagagtctgg cagccatgct ccgggcacat aacgcgggga
     1201 acatcggctt ctactaatgt catgaactgg caggtatcaa ggtggcgcca tttacgatgt
     1261 cggtgatcgt gaacagaaca ggatttcctg caggtcggac aggttaactg agtattttca
     1321 gcaattccga ctgtaacagt aacggaacct gcattttcat cgagggtaag ggatttaacc
     1381 tgccatggtg cagtcaggtt aaggatatgg gcatagaggg atttttcgtc catataattt
     1441 cattctgaag cttactttaa actgatatta ttattttttg cccactttct taatcttcca
     1501 ttagcgttgg cgtaaggcga agatgtgtta aatgagatca ttctccccat cgtccatttt
     1561 gtgtaccatg gtcttccata caaaatatca tcggtacgat cattaataag gttcacaatc
     1621 tcatttttta cagtctgaag ttcagctact aacaactcat aacttaactc actgtaatct
     1681 gagtaaaatt tttgagcaag aaggccaagc tgattccatt tatagccagt ttccggaaaa
     1741 tcgacaggca gacctttagc atcagaagcg atccacttta caacaagagc attccatcca
     1801 agcagatacg aaacgagatc acgaacactc atctccgttc ctttggcgtg tccgtccatt
     1861 gatttatctg aagtaatttc tggtgggatt gtgttgaggt aactaattaa tttactaaaa
     1921 tttttatcaa tagctaaaag cagttcagct tttgtttgcg gcacactcat aagaattccc
     1981 tctcatgtaa aaagagacac cataaaggta ctgtgtggtg tttgaaaatc actcaattat
     2041 gtaccaccca ccacaacagg ggaagaccca tatatatcca tcgattaaaa aaaggctttt
     2101 caacaacgca tccgctattg aacaaagaag ttcaggcttt aaaaaactgg ttgagtatcc
     2161 gtacttcgta cccgcatgct gagagcgagt gggtattttt atctcgtaag ggaaatccgc
     2221 tttctcggca acagttttac catattatct cgacttccgg tggtaatgcc gggttgtcac
     2281 tggagattca tccgcacatg ttacgccatt cgtgtggttt tgctttggcg aatatgggaa
     2341 tagatacgcg acttatccag gattatcttg ggcatcgcaa tattcgtcat actgtctggt
     2401 ataccgccag caatgcaggg cgtttttacg gcatctggga tagagccaga ggacgacagc
     2461 gtcacgctgt tttatagaga tagttgagat accagggatg gtgtttaaaa ctacattatt
     2521 cttacgatat atcaaaaatg attaaccatt tattaattga tgttattgta agtgtgatta
     2581 ttaattttca taataaacat taagttaacc atatccatac aaaatacaat ggtttatgtt
     2641 cttcaaaata aataaacaaa atcattcata aatttacaca tcacttaaat tctcctgttt
     2701 ccgcactttt ttctttattt tttaagcaac tggaagttaa tccactgcaa tctattgtta
     2761 tattgaatca aatcaatgaa aatagatgtt gtcacatcag tgatatttta tttttgtatg
     2821 atatttaatg taattgactg atagccacat cactccgtgt gtggttatct ttttatctat
     2881 tgggctaatt ttgaccgatt gaggtttcct ataggtattc attcaaatat atctcagtta
     2941 ggagtactac tattgtgagt aaacgtcgtt atcttaccgg taaagaagtt caggccatga
     3001 tgcaggcggt ttgttacggg gcaacgggag ccagagatta ttgtcttatt ctgttggcat
     3061 atcggcatgg gatgcgtatt agtgaactgc ttgatctgca ttatcaggac cttgacctta
     3121 atgaaggtag aataaatatt cgccgactga agaacggatt ttctaccgtt cacccgttac
     3181 gttttgatga gcgtgaagcc gtggaacgct ggacccagga acgtgctaac tggaaaggcg
     3241 ctgaccggac tgacgctata tttatttctc gccgcgggag tcggctttct cgccagcagg
     3301 cctatcgcat tattcgcgat gccggtattg aagctggaac cgtaacgcag actcatcctc
     3361 atatgttaag gcatgcttgc ggttatgaac tggcggagcg tggtgcagat actcgtttaa
     3421 ttcaggatta tctcgggcat cgaaatattc gccatactgt gcgttatacc gccagtaatg
     3481 ctgctcgttt tgccggatta tgggaaagaa ataatctcat aaacgaaaaa ttaaaaagag
     3541 aagaggtttg atttaactta ttgataataa agttaaaaaa c
//
LOCUS       DAPOXO010000196         3457 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.197, whole genome shotgun sequence.
ACCESSION   DAPOXO010000196 DAPOXO010000000
VERSION     DAPOXO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3457
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.197"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            249..1025
                     /locus_tag="ROH59_005045"
     CDS             249..1025
                     /locus_tag="ROH59_005045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX4807403.1"
                     /translation="MARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPSAHLL
                     ILLGIFGYIMHRTMPDISFPVFLLNGLIPFFIFSSISNRSVGAIEANQGLFNYRPVKP
                     IDTIIARALLETLIYDAVYILLMLIVWMAGEYFEITNFLQLVLTWSLLIILSCGIGLI
                     FMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREA
                     VMPGYISEGVSLNYLAMFTLVTLFIGLALYRTREEAMLTS"
     gene            1022..1696
                     /locus_tag="ROH59_005046"
     CDS             1022..1696
                     /locus_tag="ROH59_005046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX4807404.1"
                     /translation="MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGK
                     STLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQGSLTGRENVKFVARLYAKQEELK
                     EKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFK
                     EKCAQLFKERHKESSFLMVSHSLNSLKEFCDVAIVFKNSYIIGYYENVQSGIDEYKMY
                     QALDIE"
     gene            2074..2230
                     /locus_tag="ROH59_005047"
                     /pseudo
     CDS             2074..2230
                     /locus_tag="ROH59_005047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976766.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2681..3397
                     /locus_tag="ROH59_005048"
     CDS             2681..3397
                     /locus_tag="ROH59_005048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000634338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807405.1"
                     /translation="MIVANMSSYPPRKKELVHSIQSLHAQVDKINLCLNEFEEIPEEL
                     DGFSKLNPVIPDKDYKDVGKFIFPCAKNDMIVLTDDDIIYPPDYVEKMLNFYNSFAIF
                     NCIVGIHGCIYIDAFDGDQSKRKVFSFTQGLLRPRVVNQLGTGTVFLKADQLPSLKYM
                     DGSQRFVDVRFSRYMLENEIGMICVPREKNWLREVSSGSMEGLWNTFTKKWPLDIIKE
                     TQAIAGYSKLNLELVYNVEG"
BASE COUNT         1066 a          576 c          706 g         1109 t
ORIGIN      
        1 gttttctgaa attaccagaa gaccgaatcc attcatgcct gaagaatgga ttagaagaaa
       61 cgagacggaa atagatctat ttatccctgc ggaaataatt tctgctgaaa tttttttgcg
      121 actattaaaa aggtcaaacc gtctgagtga attttatcca gttacaaata agcattacct
      181 ccagtgtatt ggtagctgtt aagccaaggg cggtagcgta cctgaagaga ttaggatcac
      241 atcatcaaat ggcaagaagt ggatttgaag tccagaaagt caccgtagag gcattatttc
      301 tacgagaaat acgaacacgc tttggtaagt tccgtctggg atatttgtgg gcgattctcg
      361 aaccctctgc gcatttgctg atactgttgg gcatttttgg ttacattatg caccgcacga
      421 tgccagacat ctcattcccg gtgtttttac ttaatggcct gattcccttt tttatcttta
      481 gcagtatcag caatcgttct gtaggcgcta ttgaagcgaa ccaggggttg tttaattatc
      541 gaccagtaaa acccatcgat acgatcattg cacgcgcact gcttgagacg ctgatttacg
      601 atgctgttta tatattgctc atgcttatcg tctggatggc aggtgaatat ttcgagataa
      661 caaacttttt acaactagtg ctcacctgga gtttgttaat cattctttca tgtggcatcg
      721 gcttaatatt catggtcgtt ggtaaaacct tccctgaaat gcaaaaggtc ctgccgatac
      781 tgcttaagcc gctgtatttc atctcctgca tcatgttccc tctacattcg attccgaagc
      841 aatactggtc atatctactc tggaacccat tagtgcatgt cgtagagtta agccgcgagg
      901 cagttatgcc tggctatatc agcgaaggcg tgagtctgaa ctaccttgca atgttcactc
      961 tggtcaccct gttcatcggt ctggcgttat accgaactcg tgaggaggca atgctgacat
     1021 catgattaag attgagaatt tgacgaagtc atatcgtacg ccaacggggc gacactatgt
     1081 gtttaaggat ttaaacatcg aaatcccttc aggaaaaagc gttgccttta ttggtcgtaa
     1141 tggtgcgggt aaatcaacgt tactgagaat gattggtggc attgaccgcc ccgatagcgg
     1201 aaagatcatc accaataaaa cgatatcatg gccagtcggc ctcgccggtg gattccaggg
     1261 aagtttaacc ggacgcgaaa acgtaaaatt tgttgcgcgg ttatacgcga agcaagaaga
     1321 gctgaaagag aaaattgagt ttgtcgaaga atttgccgaa ctcggtaagt actttgatat
     1381 gccgatcaaa acttactcct caggtatgcg atcgcgttta ggctttggtt taagcatggc
     1441 atttaagttt gattattata tcgtcgatga agtaacagct gtcggtgatg ccaggtttaa
     1501 agagaagtgc gctcaattgt ttaaagaaag gcataaagag tctagctttt tgatggtttc
     1561 acatagtttg aattcattga aagagttttg tgatgtggcg attgttttta aaaatagcta
     1621 tattattggt tattatgaga atgttcaaag tggtatagat gagtataaaa tgtatcaagc
     1681 tttagatatt gaatgataat tatattaaat aattaactct tagttcaggt atttatatgt
     1741 tctgcttgtc attcgttggt gttaataata aaattaatat gacaaatagc atatgtatct
     1801 tatgaaattg aaacgataaa cttaatgaca caggtagaat acaagtgaca taagaaatta
     1861 tgttgctgtg gctgatataa gttctttttg ttcatttatt tttgtcgcca agcatcatga
     1921 atagaaatcc agatctccta aaatcataac aaaattgtta agataccgtt ctctgaataa
     1981 ctagactagc tccctgaatc tctaggcaat caatatcatt taaataactg atagtagtga
     2041 tactagtctt ttagactagt agttggagaa tagataattg gtgtcttaga agcagagaaa
     2101 cgcagacagc gtgccacaca ggaaaatcgc tatttttcag cagagccttg aaccgaaaat
     2161 ggcggtcttc ctcgttgcca gacaacatgg tgtggcaggc tgccagttat tctttcagcg
     2221 taagcaatac taagagggag gcctgattac tgttgcacta acagtgtcat tgccggagat
     2281 tgtaatcaca ctctatataa ttatataaac tctattgtat ttagtgtatg aggaggatgg
     2341 acagtatact ttgaactagg caattatgaa tttgatcgtg atctcgtaat acgttgctgt
     2401 tattctttaa ttaattatct gccaatttat ttttagatag ttacaggaaa tgtttatgca
     2461 aagagtggtt tgatatggta agagtaataa tttagatgaa gataaatata tcaaacgtac
     2521 accctagtag ttatttttaa ttaaacatat cgtccatgag gtgcggagtc attctaatca
     2581 acttaatgtg ttctgtttat taagcatttc ctataaataa acgactatca atacgttgat
     2641 agttttcatt aacatgcaat attaattaaa atattacccc atgattgttg caaatatgtc
     2701 atcataccca cctcgaaaaa aagagttggt gcattctata caaagtttac atgctcaagt
     2761 agataaaatt aatctttgcc tgaatgagtt tgaagaaatt cctgaggaat tagatggttt
     2821 ttcaaaatta aatccagtta ttccagataa agattataag gatgtgggca aatttatatt
     2881 tccttgcgct aaaaatgata tgatcgtact tacagatgat gatattattt accctcccga
     2941 ttatgtagaa aaaatgctca atttttataa ttcctttgca atattcaatt gcattgttgg
     3001 gattcatggc tgtatataca tagatgcatt tgatggagat cagtctaaaa gaaaagtatt
     3061 ttcatttact caagggctat tgcgaccgag agttgtaaat caattaggta cagggactgt
     3121 ttttcttaag gcagatcaat taccatcttt aaaatatatg gatggttctc aacgattcgt
     3181 cgatgttaga ttttctcgct atatgttaga gaatgaaatt ggtatgatat gtgttcccag
     3241 agaaaaaaac tggctaagag aggtctcatc aggttcaatg gaaggacttt ggaacacatt
     3301 tacaaaaaaa tggcctttag acatcataaa agaaacacaa gcaatcgcag gatattcaaa
     3361 acttaacctc gaattagtgt ataatgtgga agggtaaaaa cttacttttt tattcacatt
     3421 cctgtatttt gtgttggttt ctgaagttta tagtata
//
LOCUS       DAPOXO010000197         3336 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.198, whole genome shotgun sequence.
ACCESSION   DAPOXO010000197 DAPOXO010000000
VERSION     DAPOXO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3336
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.198"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..599
                     /locus_tag="ROH59_005049"
     CDS             <1..599
                     /locus_tag="ROH59_005049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribonuclease H"
                     /protein_id="HDX4807406.1"
                     /translation="FLDYPQLVREEKNTKNRVLKVNLFKTNDKKKYFLDLSGGAADYS
                     RFFRRHGLLCKAYEKQPPKNPVIILLDNDTGPSDFINQIIKDYSHLPKKAEDVRKGAF
                     YHLESNLYVLFTPLLPGDNYSSLEDFFEPKVLQMKYNGKSFDKSNNHDSSTTFGKDRF
                     ATYIVRENRKTIDFSLFKPILDSIIEIKKHFINLHPSK"
     gene            846..1973
                     /locus_tag="ROH59_005050"
     CDS             846..1973
                     /locus_tag="ROH59_005050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807407.1"
                     /translation="MVEKMKQNSSSTLGALSAPTTWPGANARLLGLGVGLPIAPLDRL
                     AQFSAAEFERFTLEWASEYLAGQQYVNEVQQRGGAGDKGRDIVVWLDPSDAVPRRWHL
                     YQCKHYDANLGLPKAGIEVAKVIYYTFIKDYTVPTQYHFVTHKGVTSPFQDLLDDPTK
                     LKEKMLSEWATFSKQITSKHSVDLTPELEKYIKEFDFSIFHAKQPIEILAEHSKTSFH
                     LMVFGAPLIERDPPTRPPSSVAPIETVYIEQLFSVISADIKTNVRDLVDFQSSISHVK
                     LFERSRITFYCSEGLKELARDQMANQEFFNSLLVEFDDGLYHYTSDLTGTPLLRLKNT
                     VKAAQTLQLGAHPLAIHVTNKDREGICHQLANTNLINWCNP"
     gene            1970..2485
                     /locus_tag="ROH59_005051"
     CDS             1970..2485
                     /locus_tag="ROH59_005051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807408.1"
                     /translation="MSEMQVFEGNFEQRPFNTPLEYGFRALFILDAADNVAMDLQRIV
                     SYDYLLVHTSDVPRGPKSLHPAVPHRGAELLVKRSAIQAGLHLMLSRELIKVVFAAEG
                     ILYQATNLTGRFVRLLMSQYSKELAERASWVTKQFYEYTDEELASYISQNVGQWGSEF
                     DRLTAIDLLDL"
     gene            2487..>3336
                     /locus_tag="ROH59_005052"
     CDS             2487..>3336
                     /locus_tag="ROH59_005052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807409.1"
                     /translation="MLRIRKILLRGNSVQDAYVDFYKGANILAGESDTGKSYLVSCLD
                     YILGAEKLKKKLKEATDYTHLYVEFENDEGGVLTLKRGLEGGKLEAHDVAIQDIHGEG
                     KIIAPVRKGTSKGPDVTSILFPFAGIKEAKLRKNARGETQRFSIRTLAPIFLVDEVSI
                     IDEYSPVTGRSGYDDTARKRMFSYILTGHDDGGVTVEEKPEIVKARLMAKLEFIQDLI
                     RPLDERFSICSPKFPLTSSADDLSDQLIAQAIDEVERAAAAISDLLEGIKMETALTLK
                     IESQLMG"
BASE COUNT         1018 a          634 c          742 g          942 t
ORIGIN      
        1 tgtttttgga ttaccctcag ttagttagag aggaaaaaaa cacaaagaat agagtgttaa
       61 aagttaattt atttaaaacc aatgacaaga aaaaatattt tctcgatttg tctggtggag
      121 ctgcagacta ttcgaggttt ttcagacgac atggtttact ttgtaaagcg tatgaaaaac
      181 agcctcctaa aaatccagtg ataattttat tagataatga cacagggcca tctgacttca
      241 taaatcaaat aataaaggat tattcgcatc taccaaaaaa agcggaggat gttagaaaag
      301 gggcgtttta tcacttagag agtaatttat atgttctttt tactccgtta ttaccagggg
      361 ataactattc ttcactagag gatttttttg aaccaaaagt tttgcaaatg aagtataatg
      421 gaaaaagctt cgataaaagc aataatcatg acagttctac tacatttgga aaagatagat
      481 ttgctactta tatagtaagg gaaaatagaa aaactatcga tttttcatta ttcaaaccca
      541 tacttgattc aattattgaa atcaaaaaac attttatcaa tctacaccca tcaaagtgat
      601 ggttatgaaa agagataaaa atgctgatgt caaaagaggc ttatgctcgg cacagtggag
      661 tgagctgcca aactgtcgat gactgggtag ccggtggggc ggaagtagtt atgtcccgta
      721 gcaaggttaa gatttgctct tgtgtgtggg gaaccttagt caattacttt cctggcgcac
      781 tgtgttagat tttgtaaaat tttaaaagac taaagattta atatcacttc tccatggagg
      841 ttgtggtggt agagaagatg aaacaaaatt caagttcgac gcttggcgcg ctttctgctc
      901 ctacaacgtg gccgggtgcg aacgctcggc tgcttgggtt aggtgtaggg cttccaatag
      961 cccccttgga tcgtctggca cagtttagcg ccgccgaatt tgaaaggttt acactcgaat
     1021 gggcctctga atacttagct ggtcagcaat atgtcaacga agtacaacaa cgtggcgggg
     1081 caggagataa aggcagagat attgttgtat ggcttgatcc atctgatgct gttcctcgaa
     1141 gatggcactt atatcaatgc aaacattatg atgcgaattt aggccttcct aaggcaggca
     1201 tcgaagttgc aaaagttatc tattatactt tcatcaagga ctacacagta cctacacaat
     1261 accattttgt tacacataaa ggggtaacat cgccattcca agacctccta gatgatccaa
     1321 ctaaactcaa agagaaaatg ctatccgagt gggcaacttt ttcaaagcaa attacatcga
     1381 aacatagtgt tgacctgacg cctgaacttg aaaaatatat taaagagttt gattttagta
     1441 tttttcatgc aaaacagcct attgagatac ttgccgaaca cagtaaaacc tcttttcatc
     1501 ttatggtctt tggcgcacca ttaattgagc gggatccacc aactaggccc ccatcatctg
     1561 tggctcccat tgaaactgta tatattgaac aactcttttc agttatcagc gctgatatca
     1621 aaaccaacgt gcgagattta gttgattttc aatcaagtat cagccatgta aaactctttg
     1681 aacggtcccg aataactttt tattgctcgg aagggctaaa ggaactcgct agggaccaaa
     1741 tggcgaatca agaattcttt aattctttac ttgtagagtt tgatgatggt ctgtatcact
     1801 acacctctga cctgacaggg actccactcc ttcggttaaa aaataccgtc aaggccgctc
     1861 agaccctgca acttggtgcg cacccacttg ccattcacgt aacgaataag gatcgtgaag
     1921 gtatatgcca ccaactagcc aatacaaact tgattaattg gtgcaatcca tgagcgaaat
     1981 gcaagtattt gaaggaaact ttgagcagag accttttaac actccgctgg agtatggatt
     2041 tcgtgctctg ttcatattgg atgcagcgga caatgtagca atggacctac aaaggatagt
     2101 ttcgtatgac tatcttcttg tgcataccag tgacgtacct agggggccta aaagccttca
     2161 tccagcagtt cctcaccggg gagcagagct tcttgttaag cgaagcgcaa ttcaggcagg
     2221 gctgcattta atgctatcaa gagaattgat taaggttgtc tttgctgccg aaggtatttt
     2281 gtatcaggct accaatttaa caggaaggtt tgtgcggctt ttgatgtcac agtattcaaa
     2341 agagctcgca gaacgtgcct cttgggtcac aaagcaattc tatgaatata cggatgaaga
     2401 acttgcttca tatatatctc agaatgtggg gcaatggggt tctgaattcg accgattgac
     2461 cgcaattgat ctactggatt tataacatgc ttcgtataag aaaaatacta ttgcgcggaa
     2521 acagcgttca agacgcttat gttgatttct ataagggtgc gaatattcta gcaggggaat
     2581 ctgatactgg gaaaagttac cttgtgagtt gtcttgacta cattcttggt gccgaaaaac
     2641 tcaaaaaaaa gcttaaagag gccaccgatt acacccatct ttatgttgaa ttcgaaaatg
     2701 atgaaggggg ggtgttaacg ctcaagcgcg gtcttgaggg ggggaaatta gaggcacatg
     2761 atgtcgctat tcaagacatc catggagaag gtaaaataat tgctcctgtg cgtaaaggaa
     2821 cgagtaaggg gccagatgtg acgtccatac ttttcccttt tgcggggatc aaagaggcga
     2881 agcttcgcaa gaatgctcgt ggcgaaacgc aacgtttctc gattcgaacg ctcgctccta
     2941 tatttttggt agatgaagta tccattatcg acgaatactc gccagtaacg ggacgttccg
     3001 gttatgacga cactgctcga aaacgcatgt tttcatacat ccttaccggg cacgatgatg
     3061 gtggtgttac cgtagaggaa aagcctgaaa ttgtaaaagc gaggttgatg gcgaagcttg
     3121 aattcatcca ggatttgatt cgaccacttg atgaacgttt ctcaatttgt tcgcccaagt
     3181 ttccattaac gagctcagca gatgatttat cagatcaatt gattgcacaa gcaattgatg
     3241 aagttgagag ggctgcagcc gctatttctg acttgctcga gggaataaaa atggagacag
     3301 cgttaacgtt aaaaatagaa tctcagttaa tgggag
//
LOCUS       DAPOXO010000198         3268 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.200, whole genome shotgun sequence.
ACCESSION   DAPOXO010000198 DAPOXO010000000
VERSION     DAPOXO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3268
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.200"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..414
                     /gene="ftnA"
                     /locus_tag="ROH59_005053"
     CDS             <1..414
                     /gene="ftnA"
                     /locus_tag="ROH59_005053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HDX4807410.1"
                     /translation="AWCSYHTFEGAAAFLRRHAQEEMTHMQRLFDYLTDTGNLPRINT
                     VESPFAEYSSLDELFQETYKHEQLITQKINELAHAAMTNQDYPTFNFLQWYVSEQHEE
                     EKLFKSIIDKLSLAGKSGEGLYFIDKELSTLDTQN"
     gene            complement(452..691)
                     /locus_tag="ROH59_005054"
     CDS             complement(452..691)
                     /locus_tag="ROH59_005054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HDX4807411.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSEEGFSTDQSKICRH"
     gene            882..2093
                     /gene="tyrP"
                     /locus_tag="ROH59_005055"
     CDS             882..2093
                     /gene="tyrP"
                     /locus_tag="ROH59_005055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HDX4807412.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNIRKLRWVF
                     IIGSAIPLVAYIFWQLATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
     gene            complement(2144..2809)
                     /gene="yecA"
                     /locus_tag="ROH59_005056"
     CDS             complement(2144..2809)
                     /gene="yecA"
                     /locus_tag="ROH59_005056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HDX4807413.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPAQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
BASE COUNT          762 a          804 c          785 g          917 t
ORIGIN      
        1 gcctggtgca gctatcatac cttcgaaggt gctgccgcgt tcctgcgccg tcacgcccag
       61 gaagagatga cgcatatgca gcgtctgttt gattacctga ctgataccgg caacttaccg
      121 cgtattaata ccgttgaatc tccgtttgct gaatattcct cacttgatga attattccag
      181 gaaacctata aacacgaaca attaatcacg cagaaaatta acgaactggc tcatgctgca
      241 atgaccaatc aggactaccc aacatttaat ttcctgcaat ggtatgtttc tgagcagcat
      301 gaagaagaga aactgttcaa atcgattatt gataaattaa gcctggcagg caaaagtggc
      361 gaaggtctgt attttatcga caaagaactc tctaccctcg acacacaaaa ctaatgctct
      421 ccggcggcag gttttctgcc gccgtttcaa atcagtgacg gcaaatctta ctctgatcgg
      481 ttgaaaaacc ttcttctgaa ggtataaatt tgccttttgc tgccagaaac gccaccaact
      541 ctcccgcagt catcccttct gccgagcagg tgtgaaaacg tgcctgttca ccaaaacgcg
      601 ctttaattgc tgcttccaga ctggcatgcg tatattgctc gcctgattca atcatcatat
      661 ttaacacttc atgaccgtga atagagtcca tcgttcctcc tcaaaaaaag cctagcgtag
      721 cgattgctgc ttatgaagac tttgcgccag cgcagaactg aacgcttttt attgtacatt
      781 tatatttaca ctatatgtaa cgtcgatttg acgaatcagc cgttatgcct taacctgcgc
      841 cgcagatatc actcataaag atcgtcagga cagaagaaag cgtgaaaaac agaactctgg
      901 gaagtgtttt tatcgtggcg ggaaccacaa ttggcgcagg catgctggca atgccgctgg
      961 ctgcggcagg tgttggtttt agcgtcacgt taatcttgtt gattgggctt tgggcgttga
     1021 tgtgctacac ggcgctatta ctgctggagg tgtatcagca tgtcccggca gataccggtc
     1081 tgggcacgct ggcaaaacgc tatctgggac gctacggtca gtggctgacg ggcttcagta
     1141 tgatgttctt aatgtatgct ctgactgcgg catacatcag cggtgccggt gaattgttgg
     1201 cctccagcat cagcgactgg acaggtattt caatgtcggc aaccgctggc gtgctgttgt
     1261 tcacttttgt tgccggtggc gtggtttgtg tcggaacttc gctggtcgat ttatttaacc
     1321 gttttctgtt cagcgccaaa attatttttc tggtggtgat gctggtattg ctgctaccgc
     1381 atattcacaa agtgaatctt ttaaccctgc cgttgcaaca gggactggca ctgtctgcaa
     1441 tcccggtgat ttttacgtcg tttggttttc acggtagcgt gccgagtatt gtcagctata
     1501 tggatggcaa cattcgtaag ctacgctggg tgtttataat cggtagtgcg atccccctgg
     1561 tggcatatat tttctggcag ctggcgaccc ttggcagcat tgattcaaca acctttatgg
     1621 gattgctggc taatcatgcc ggattaaacg ggctgttaca ggcgttacgc gaaatggtgg
     1681 cctctccgca tgttgagctg gcagtgcatt tatttgctga tttagccctc gccacgtcct
     1741 tcctcggcgt agcgttaggc ttatttgatt atctggcaga tttgtttcag cgttcaaata
     1801 ccgttggtgg acgattgcaa actggtgcaa ttacctttct gccgccactg gcgtttgcac
     1861 tgttttatcc acgaggattt gtgatggcgc tgggttacgc cggtgtggca ctggcggtac
     1921 tggcattgat tatcccttcg ctgttgacct ggcaaagcag gaagcacaat cctcaggcgg
     1981 gttaccgggt gaaaggtggt cgtccggcgc tggtggtggt gtttctctgt ggtattgctg
     2041 tgattggcgt gcaatttttg attgcggcag gcttgttacc agaagtgggg tgattagatt
     2101 cttattgggt gccagaatta acgctgacac ccaatttgac ctcttaatgc aggcagcact
     2161 gcttaaattt cttaccacta ccgcacgggc aaggatcatt acgccccggt ttctcttctg
     2221 ctttgatcgg ttgctgaaca gctttttcct gcggatgcgc catccagtac gcatgtagat
     2281 caagcgccgc cagtcgaatg gcatctacgc tctcttcaaa cgcttctggc gacatcttct
     2341 ctacccgctc gaagttttcc tcagtaccgt gcagcgcaat cgcctccagc gctggtttta
     2401 acgaatcggg caacgttgac cagtcagaaa gtgccacgcc ccgcatatag ccaaagcacc
     2461 actcctcaac aatcgtcagc tcgctgccat cgacttctcg caagccgaat aatggctcaa
     2521 actgctccgg aaattcgttc agacgctctg cggtatcggc catatgttga aaagccaggt
     2581 tcataaagcg cgtcatctct ttctctgacg cccagcgcgg cacatagtca gccccacccc
     2641 acacggcaac cagccactgt gccggttcaa tctcttgcgg agaactcaac accgccgtca
     2701 ataaaccgtc cagctccgcc acatcaagaa tggcgtggtc agtgttgtat ttggtcagaa
     2761 tatcgtccag ccattccaac tcactttcgt ttaacggtcc cgttttcata cgcttttcct
     2821 tgtggatctc aactcgccag cacctatctt acatgccggt ccgtatcaga gatacttttt
     2881 gagtggcttt gccggtgatt aaaaattaag gagggtgtaa cgacaagttg caggcacaaa
     2941 aaaaccaccc gaaggtggtt tcacgacact gcttattgct ttgattttat tcttatcttt
     3001 cccatggtac ccggagcggg acttgaaccc gcacagcgcg aacgccgagg gattttaaat
     3061 tggtcgcttt gtgcaataaa ttcaaataat tatggcaaat tatccggaca taatggtgtg
     3121 tatgaatatc aaataatcat atagttacga cgcgtcttac tcatcgtctt ctgaaggttt
     3181 ttggcaaaaa tggtgatgtt ctgcgccttt atgtgaccaa actgtcagga gcaaagcgag
     3241 gtaaaggggt atgagaaaaa ctcacata
//
LOCUS       DAPOXO010000199         3226 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.201, whole genome shotgun sequence.
ACCESSION   DAPOXO010000199 DAPOXO010000000
VERSION     DAPOXO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3226
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.201"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..421
                     /locus_tag="ROH59_005057"
     CDS             <1..421
                     /locus_tag="ROH59_005057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX4807414.1"
                     /translation="KLKENFPNDRESIFHINVMAIPPITNDEKDSNNAVQFAINTRIK
                     LIYRPHKINNKNQVSDAYKNLKITSSKETLTVSNPSPYYITMNDVKINGKNITSIKDF
                     MVSPFSTLIIPEKNAKTISYSTINDYGGETPIQNIKL"
     gene            454..2991
                     /locus_tag="ROH59_005058"
     CDS             454..2991
                     /locus_tag="ROH59_005058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX4807415.1"
                     /translation="MKGSLKKSLLLLRITIICPVFSCAAVSPSPDNSHRFSFNPDFLQ
                     LSDGDNAKNIDLNYFANASGAAPGEYTVDVVMNGELVDRQIKIDFFAQDNKLNARLTP
                     QQLERWGIDTNKLSVSSPSAYQQNIAYIIQGATEKFDANNQKLILNIPQSYLKPQDWL
                     STPPHLWDEGMPALMVNYLFNGIKQNNNGYGSRSQFLSLDSSLNLGGWRLRHNGNWST
                     NSYNKESHWQPVSVYLQHDYSFLQGGQFTVGQTSTDGAIFDSFPFEGAQFSSDDGMIA
                     PELSQYSPVVRGIAYSQAQVSVKQNGVVIYQKNVPPGPFELRDFNQIFTGDLEVEIRE
                     ADGTIRHFTQATAVLPILQRQGRLRYNLAFGKYRSSSTLNNSVSEPQFVQSSAAIGLP
                     YEYTFYGGGIKADNYAAVLLGLGKYSDFFGAFSLDVTHARSQFSQNYKSFGKQQGQSY
                     RFMYSRGFGETNTTLNITGYRYATRGYYDFDELQQIQSGFVDEKNINSYHQRSRISTT
                     ISQDLQDWGQLYLSASKDQYWDTADGYNLSASYSLPFRYISAMLSLGYNKSPYYHEAD
                     KSLFLSVSVPLNSLLNGNNLFLTTNTITNNGQVQQQVGLNGSSQDGEFNYAVAQGWQN
                     QNRGESGNINLNYRGPYAQMNGGYAWQKESSQWTYGISGGITLHPHGLTLSQPLSLDS
                     ASALVQARDAASVKVLNGSGIYTDWRGYAVVPYLNPYNRNQISLDVNSVKDNVELLNT
                     DVTVIPSRGALVSAPFKVNVGNKAIITLIQKNGEPVPFGSVVTLDSENSINSSIVADQ
                     GQVYMSGLPEEDTLIAQWGEEASQKCKTNYKLQNKKAKFSELTLQCQ"
     gene            complement(3101..>3226)
                     /locus_tag="ROH59_005059"
     CDS             complement(3101..>3226)
                     /locus_tag="ROH59_005059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX4807416.1"
                     /translation="GKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKIREYDDIRS"
BASE COUNT          987 a          660 c          650 g          929 t
ORIGIN      
        1 caaattaaaa gaaaattttc ctaacgacag ggagagcata ttccatatca atgttatggc
       61 tattcctcca atcacaaatg acgaaaagga tagtaacaat gctgttcaat ttgccatcaa
      121 cacaaggata aaattaatat atcgcccaca taagataaac aacaaaaacc aagtttctga
      181 tgcttataaa aacttaaaaa taacatcttc aaaagaaaca ttaactgtct caaaccctag
      241 cccatactat attaccatga acgatgtaaa gattaatggg aaaaatatta catctataaa
      301 ggattttatg gtttcaccat tttcaacatt aatcatcccg gaaaaaaatg ctaaaacaat
      361 tagttattct acgataaatg attacggcgg agaaacgccg attcaaaaca ttaaacttta
      421 acatttattt aatcatcttt atcgggggac aatttgaaag gttcattaaa aaaatcctta
      481 ttattgttaa ggatcaccat catatgtccg gtattcagtt gcgctgccgt atctccctca
      541 cctgacaata gtcataggtt ctcatttaac cccgattttt tgcaattatc tgatggtgat
      601 aatgccaaaa atatcgatct caattatttt gcaaacgcaa gcggtgcagc tccaggggaa
      661 tatactgttg atgtagttat gaatggggaa ttagttgacc gtcagattaa gatagatttt
      721 ttcgcgcagg acaacaagct gaacgccaga ctgacgcctc aacagttgga acgttgggga
      781 attgatacaa ataagctctc cgtatcttcc ccatcggctt accagcaaaa tattgcatat
      841 attattcagg gcgcaacaga gaaattcgat gcgaacaacc aaaagctaat attgaatata
      901 ccacaaagct acctcaaacc tcaggattgg ttaagtactc cgccccatct ctgggatgaa
      961 ggtatgccag cgctaatggt taactatcta tttaacggaa ttaagcaaaa taataatggc
     1021 tacggtagcc gtagtcagtt tttatctctg gacagttctc tgaaccttgg tggatggcgc
     1081 cttcgccata acggtaactg gtcaacaaac tcatataata aagagagcca ctggcaaccc
     1141 gttagtgttt atctacagca tgattattct ttcctgcagg gagggcaatt tactgtaggg
     1201 caaacctcaa cggatggtgc gatatttgac agttttcctt ttgaaggagc acagttttca
     1261 tctgatgatg gcatgattgc cccagaactc agccaatata gtcctgttgt ccgtggcatt
     1321 gcttattctc aagcacaggt atccgtcaag caaaacggag ttgtcattta tcaaaagaac
     1381 gtcccacctg gaccgtttga attacgcgat tttaaccaaa tattcaccgg tgacctggag
     1441 gtggaaatcc gtgaggcaga tggcactatt cgccatttta ctcaggcgac ggccgtttta
     1501 ccgattctgc aacgtcaggg gcgcttacgc tataacctgg cattcgggaa atatcgctca
     1561 agttctactt tgaataatag tgtgtctgag cctcagtttg ttcagtcttc agcagcaatc
     1621 ggattacctt atgaatatac attttatggt ggtggtatca aagcagacaa ctatgcagca
     1681 gttctgcttg gcctgggtaa atactcagat ttttttggag cgttctccct ggatgtcact
     1741 catgctcgct cacaattttc gcagaattat aagtctttcg gaaaacagca aggacagtct
     1801 taccgcttta tgtattcgcg tggttttggt gagacgaata cgacattgaa tattaccggc
     1861 tatcgttatg ccacacgcgg ttactacgat tttgatgagt tacaacaaat tcagagtgga
     1921 ttcgttgatg agaaaaatat aaacagttat catcaacgtt cgcgtatatc aacaacgata
     1981 agtcaagatc ttcaggattg gggacaactc tacctctcag caagtaaaga tcagtactgg
     2041 gataccgctg atggatataa cttatctgcg agttactcgc tgccattccg ctatatctcg
     2101 gcaatgctat cgctcgggta taataaaagc ccgtattacc acgaggctga taaatcgctg
     2161 tttttatctg tgtctgtacc gctcaactca ttgctgaatg gaaataacct gttcttaacc
     2221 acgaatacca ttacgaataa tggtcaggtg caacagcagg ttggattaaa cggctcctca
     2281 caggatggtg agtttaacta tgccgtggcg caaggctggc agaatcaaaa cagaggagag
     2341 tcaggtaaca ttaaccttaa ctatcgtgga ccttatgcac aaatgaacgg cggctatgcc
     2401 tggcaaaaag aatccagtca atggacatac ggaattagcg gtggtattac gttgcatcca
     2461 catggattaa ccttatccca gccattaagt ctggacagtg ccagtgctct ggttcaggct
     2521 cgtgatgccg ccagcgtaaa agtattgaac gggtcaggta tttatacgga ctggcgtgga
     2581 tatgccgtgg tcccatattt gaatccctat aaccgaaatc aaatttcact tgatgttaat
     2641 agtgttaagg ataatgttga gctgctaaat acagatgtta ctgtcatccc ttctcgagga
     2701 gctttagttt ccgctccatt taaagtcaat gtcggtaata aggcaataat taccttgata
     2761 cagaagaatg gtgagcccgt accgtttggt agtgtggtga cattagattc tgaaaatagc
     2821 attaacagca gtattgttgc tgatcaagga caggtgtata tgtcagggtt acctgaagag
     2881 gatacactta ttgcacaatg gggtgaggag gcttctcaaa agtgtaaaac aaattacaaa
     2941 ttgcaaaata aaaaagcgaa attcagtgaa ttaactttac aatgccaata gtcggtagtt
     3001 cttagattaa taaccctgca tatgcggggt tattttcatc taacatatta acaacatcat
     3061 tccagatttg tattacttcc ggcggacaca aatcatcttt tcaactgcga atatcatcat
     3121 actcccgtat tttatcaaat tcgtgtttcg caaatgggca tagtgggata atttttcgtt
     3181 tttcccgacg cattttttcc acgactttcg caaccagctg tttacc
//
LOCUS       DAPOXO010000200         3013 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.202, whole genome shotgun sequence.
ACCESSION   DAPOXO010000200 DAPOXO010000000
VERSION     DAPOXO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3013
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.202"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(586..744)
                     /locus_tag="ROH59_005060"
     CDS             complement(586..744)
                     /locus_tag="ROH59_005060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDX4807417.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAA
                     FMAYESGK"
     gene            complement(1020..1739)
                     /locus_tag="ROH59_005061"
     CDS             complement(1020..1739)
                     /locus_tag="ROH59_005061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HDX4807418.1"
                     /translation="MSARSQALVPLSTEQQAAWRAVAETEKRRHQGNTLAEYPYAGAF
                     FRCLNGSRRISLSDLRFFMPSLTAEELHGNRLQWLYAIDVLIETQGEVCLLPLPGDAA
                     ERLFPSVRFCVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVAQAEIELAFHSPE
                     TVGSWHARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEASLAAKE
                     AGHAVREMERWMVPNKLREVA"
     gene            complement(1736..2170)
                     /gene="psiB"
                     /locus_tag="ROH59_005062"
     CDS             complement(1736..2170)
                     /gene="psiB"
                     /locus_tag="ROH59_005062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HDX4807419.1"
                     /translation="MKTELTLNVLHTMNAQEYEDIRAAGSDERRELTHAVMRELDAPD
                     NWTMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQVWVLVLVNAGGEPFAVV
                     QVQRRFAPEAVSHSLALAASLDTQGYSVNDIIHILMAEGGQV"
     gene            complement(2225..>3013)
                     /locus_tag="ROH59_005063"
     CDS             complement(2225..>3013)
                     /locus_tag="ROH59_005063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807420.1"
                     /translation="NVCVQRGVQLRSEDDAADDADRTEQVQEKASVEEISLPLLTKMS
                     SERTLAVQAALMQQPDKSLTLLAWTLCLNVFGSGAYSKPAQISLECKHYSLTSDAPSG
                     KEGAAFMALMAEKARLAALLPEGWSRDMTTFLSLSQEVLLSLLSFCTACSLNGVQTRE
                     YGHTSRSPLDTLESAIGFHMRDWWQPTKANFFGHLKKPQIIAALNEAGLSGAARDAEK
                     MKKGDAAEHAEHHMKDNRWVPGWMCAPRPQTDATERTDNLADAA"
BASE COUNT          645 a          914 c          815 g          639 t
ORIGIN      
        1 ccgccgcaac gacgtgaagc acggtttgcg aaacggcgtt gcgccttaca tcccggcggc
       61 cttttgccgg gatgccagga gcgcaggcca cggcgcgaca gaggcggcgc gaccggaacg
      121 gtcgctgcaa gcccggggtt tcgcgtcagg gatggaagcc cgccagggcg gagacagctt
      181 cgctggctcc gttcacgaca gcccgccccg ccagggggac gcccggaaaa ggcataagca
      241 ggagaacaac aaaacagaca ataatcaggg cagcagtaat cagagtcaga gcagtaatca
      301 gagtcagagc aggaggaaaa agagaataat caaagggaag gtgatgtgat ttctggcaag
      361 tcataaacag agaaggcggg ggaaaagaac gggcgccgca ggcgcacgtt catccccgtt
      421 cccggaggga aacggccttc ctggcagtct ggttgttcag cccgtacaat gccagcaagg
      481 agaaagggac caccggcgaa ccagcagccc ctttataaag gcgcttcagt gcagtcagac
      541 cagcatcagc cctgaaaagg cgggcctgcg cccgcctcca ggttgctact taccggattc
      601 gtaagccatg aaagccgcca cctccctgta tccgtctctg taacgaatct cgcacagcga
      661 ttttcgtgtc agataagtga atatcaacag tgtgagacac acgatcaaca cacaccagac
      721 aagagagctg cgtggtagtt tcatggcctt cttctccttg cgcaaagcgc ggtaagaggc
      781 tatcctgatg ttgtctaagc atgcaggggc ctcgtgggtt aatgaaaaat taactacggg
      841 gcttttgtcc ttctgccaca caacacggta acaaaccacc ttcacgtcat gaggcagaaa
      901 acctcaagcg ccgggcacat catagcccat ataccagcac gctgaccaca ttcacttttc
      961 ctgaaaataa ctcgctcatt caggctgttt acgggcaatc cgttgtgatt gttgccgcat
     1021 cacgccacct cccggagttt gttcggcacc atccaccgct ccatctcacg gacagcatga
     1081 ccggcctcct ttgctgccag actggcttcc gcgataacct gccagaatgg catatcctgc
     1141 cactgccagc gttccattcc ggccagtgac ggaaaacgct cgccccactg ccagaacagg
     1201 gtttccaggt catgctctgc cacccgatca ctccagcgtg catgccagct tccgactgtt
     1261 tccggtgaat ggaacgccag ttcgatttca gcctgggcga ccagcgcctg gtacgcacgg
     1321 gctttctgct ctgcctccct cgcctgctgg cggctgtact tctgcatgac cagcgcggat
     1381 ttatggcgac tgcgttccct gacacaaaac cgcaccgacg ggaacaagcg ttctgctgca
     1441 tcaccgggaa ggggaaggag gcagacctcg ccctgtgttt caatcagcac atcgatggca
     1501 tacaaccact gaagacggtt tccgtgcagt tcttctgcgg tcagggatgg catgaaaaat
     1561 cgcaggtcag acagcgatat cctgcggctt ccgttcagac agcggaaaaa cgcccccgca
     1621 tacggatatt ccgccagcgt gtttccctga tggcggcgtt tttccgtctc tgccactgcc
     1681 cgccatgcgg cctgttgctc tgtgctgagg ggaaccagtg cctgtgaacg tgcgctcata
     1741 cctgacctcc ttccgccatc aggatatgga tgatgtcgtt aacgctgtat ccctgcgtat
     1801 ccagtgacgc cgccagtgcc agtgaatggc tgacggcttc cggtgcaaac cgccgctgta
     1861 cctgaaccac cgcaaacggc tcaccaccgg cattcaccag aaccagcacc cagacctggg
     1921 agacatcgcc cggtgaacat aacgccaggt gaaaacgttc gtgggcaggc gtgaaacgga
     1981 cctggacggg gaaaaagccg ccaaactcgc tgccgtactc gccgttcatc gtccagttgt
     2041 ccggcgcatc cagttcccgc atcacggcgt gtgtcagctc acgacgttca tcacttccgg
     2101 cagcccggat atcttcatat tcctgtgcgt tcatggtatg taatacattc agagtcagtt
     2161 cagttttcat cacggtatct cccttgctgc cgccccgtct ccggcggggc gatgtggttg
     2221 ttcatcaggc ggcatcagcc aggttatcgg tgcgttcagt ggcatccgtc tgtgggcgtg
     2281 gtgcacacat ccagccaggc acccagcggt tgtctttcat atggtgctct gcatgttcag
     2341 ccgcatcgcc tttcttcatc ttctccgcgt cccgtgcggc accggatagt cctgcctcat
     2401 tcagggctgc gataatctgc ggctttttca ggtgtccgaa aaagtttgct ttcgtcggct
     2461 gccaccagtc gcgcatgtga aagccgatgg cgctctccag cgtgtccagc ggactgcgtg
     2521 acgtgtgacc atactcacgg gtctggacac cgttaaggct gcatgcggtg cagaaactga
     2581 gcagggataa cagcacctcc tgactgagtg acaggaatgt cgtcatgtcc cgtgaccatc
     2641 cctccggtaa cagggcagca agacgggctt tttctgccat cagcgccatg aatgcggcac
     2701 cttccttccc cgatggcgca tcgctggtca gcgaataatg tttacattcc aggctgattt
     2761 gtgctggttt actgtacgct ccgctgccaa acacattcag gcagagcgtc catgccagca
     2821 gtgtcaggga tttgtccggt tgctgcatca gtgctgcctg gactgccagc gtgcgttcgg
     2881 aagacatttt cgtcagcagt ggcagactga tttcctccac tgacgctttt tcctgcacct
     2941 gttccgtgcg gtcagcgtcg tcagccgcat catcctcact gcgtaactgc acaccacgct
     3001 ggacacatac gtt
//
LOCUS       DAPOXO010000201         2955 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.203, whole genome shotgun sequence.
ACCESSION   DAPOXO010000201 DAPOXO010000000
VERSION     DAPOXO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2955
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.203"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1933)
                     /gene="nikB"
                     /locus_tag="ROH59_005064"
     CDS             complement(<1..1933)
                     /gene="nikB"
                     /locus_tag="ROH59_005064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type relaxase NikB"
                     /protein_id="HDX4807421.1"
                     /translation="MNAVIPKKRRDGKSSFEDLVSYVSVRDDMTDEELNLSSSSQAEQ
                     PHRSRFSRLVDYATRLRNESFVALVDVMKDGCEWVNFYGVTCFHNCTSLETAAADMEY
                     IAQQAHYAKDNTDPVFHYILSWQAHESPRPEQIYDSVRHTLKSLGLGEHQYVSAVHTD
                     TDNLHVHVAVNRVHPVTGYLNCLSWSQEKLSRACRELELKHGFAPDNGCWVHAPGNRI
                     VRKTAVERDRQNAWTRGKKQTFREYVAQTAVAGLRSEPVNDWLSLHRRLAEDGLYLSQ
                     MDGKFLVMDGWDRNREGVQLDSFGPSWCAEKLMKKMGDYTPVPKDIFSQVEAPGRYNP
                     DFIAADVRPEKIAETESLQQYACRHLGERLPEMAREGRLENCQAIHRTLAEAGLWMRV
                     QHGHLVICDGYDHNQTPVRADSVWSLLTLDNVNQLDGGWQPVPTDIFRQVTPTERFRG
                     RRMESCPATDKEWHRMRTGTGPQGAIKRELFSDKESLWGYSISHCSPQIEEMITQGEF
                     TWQRCHELFAQQGLMLQKQHHGLVVVDAFNHEQTPVKASSIHPDLTLGRAEPQAGPFV
                     SAPADLFDRVQPESRYNPELAVSDRYGVSSKRDPMLRRQRREARAEARADLRARYLAW
                     REQWRKPDLRYGERCREIHQ"
     gene            complement(1944..2276)
                     /gene="nikA"
                     /locus_tag="ROH59_005065"
     CDS             complement(1944..2276)
                     /gene="nikA"
                     /locus_tag="ROH59_005065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type relaxosome accessory protein NikA"
                     /protein_id="HDX4807422.1"
                     /translation="MSDSAVRKKSEVRQKTVVRTLRFSPVEDETIRKKAEDSGLTVSA
                     YIRNAALNKRINSRTDDAFLKELMRLGRMQKHLFVQGKRTGDKEYAEVLVAITELTNT
                     LRKQLMEG"
     gene            2510..2845
                     /locus_tag="ROH59_005066"
     CDS             2510..2845
                     /locus_tag="ROH59_005066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
                     /protein_id="HDX4807423.1"
                     /translation="MASKKFYSDDDIQLAKAALSELPDLTAQRKTLRDFLDAIRDDII
                     ILVRTKGYTLADVRDTLKNAGYEVGEKALRDIIREAESKKTSRRSSSKTAPKKTDSGR
                     KDGIDMNNN"
BASE COUNT          737 a          772 c          686 g          760 t
ORIGIN      
        1 cctgatgaat ttcccgacaa cgttccccat aacgcagatc tggtttacgc cattgttcac
       61 gccatgccag atagcgggca cgcaggtcag cacgggcctc agctctggct tcacgtcgct
      121 gccggcgcag cattgggtca cgtttactgc tgaccccgta cctgtcactg acagccagct
      181 ccgggttata gcgactttca ggttgcaccc tgtcaaacaa atctgctggg gcactcacaa
      241 aaggtccggc ctgtggctct gcacgcccca gtgtcagatc aggatgaatg ctgctggcct
      301 tcaccggcgt ttgctcatga ttaaaggcat caacgacaac aagcccgtga tgttgtttct
      361 gtagcatcag tccctgttgt gcaaacagct catgacaacg ctgccaggta aactcacctt
      421 gtgtgatcat ttcttcaatc tgagggctac aatggctgat gctgtatccc cacagacttt
      481 ctttgtcaga aaacagttcg cgtttgatag ccccctgcgg ccccgtgcct gtacgcatac
      541 ggtgccattc tttatcggtc gcaggacagc tctccatacg acgaccacgg aagcgttctg
      601 ttggcgtaac ctggcggaaa atatctgttg gtacaggctg ccagccacca tcgagttgat
      661 tcacattgtc gagcgtcagc agcgaccata cgctgtcagc acgaacggga gtctggttat
      721 gatcataacc gtcacagata accaggtgac catgctgaac acgcatccat aatcccgctt
      781 cagccagtgt gcggtgaata gcctggcagt tttccagccg tccttcccgt gccatttccg
      841 gcagacgttc tccaaggtga cgacaggcat actgctgcag actttctgtt tcagcgattt
      901 tttccgggcg aacatcagcg gcaatgaagt ccggattata gcgtcctggt gcttccacct
      961 ggctgaaaat gtcttttggt actggcgtgt agtcacccat ttttttcatg agtttttctg
     1021 cacaccagga gggaccaaac gagtcaagct gtacaccttc cctgttgcga tcccagccat
     1081 ccatcaccag aaattttccg tccatctgag acaggtacag accatcttcc gcaagacgac
     1141 gatgcaggga taaccagtca tttacaggtt cactgcgtaa accagcgacc gctgtctgcg
     1201 cgacatactc gcgaaaagtt tgtttttttc cgcgtgtcca cgcgttctgg cgatcacgtt
     1261 caacggcagt tttgcgaacg atacgatttc ccggcgcatg gacccagcaa ccgttatccg
     1321 gagcaaaacc atgcttcagt tcaagctcac ggcaggcacg gctgagtttt tcctgactcc
     1381 atgaaaggca attcagataa cctgtaaccg gatgtacccg gttgaccgca acgtgaacat
     1441 gcaggttatc agtatcggta tgtacggcag aaacatactg atgttcaccc agcccgaggg
     1501 atttcagggt atggcgtaca ctgtcataaa tctgttccgg acgcgggctt tcatgggcct
     1561 gccaggaaag aatgtagtga aaaacaggat cagtattatc tttcgcatag tgtgcctgct
     1621 gtgcaatgta ctccatatct gcagcagcag tttcaagcga tgtacagttg tgaaaacagg
     1681 tcacaccgta aaagttaacc cattcgcagc cgtccttcat gacatcaacc agcgccacga
     1741 atgactcatt tcgaaggcgt gtcgcataat caacaaggcg actgaaacgg ctccggtgcg
     1801 gttgttcagc ctgcgaagaa gaagataaat tcagttcctc atcggtcatg tcatcccgga
     1861 ccgagacgta ggacaccagg tcttcgaacg aagacttgcc gtcccttctc tttttcggaa
     1921 tgactgcatt caccggagaa tcctcaacct tccattaact gtttacgcaa tgtatttgta
     1981 agttcggtta tggcaacaag cacttctgcg tattccttgt caccggttct ttttccctga
     2041 acaaacagat gcttctgcat ccttcccagt ctcattaact ccttcagaaa agcatcatct
     2101 gtacgggagt taattcgctt attcagtgct gcatttcgga tgtaagcaga tacagtaagt
     2161 ccggaatctt cagctttttt cctgatggtt tcatcctcaa caggagagaa tctgagtgtc
     2221 ctgacaactg tcttttgccg tacctcactt ttctttctta ccgcactatc actcacttca
     2281 ggctccttac ggggtgtcgg ggcgaagccc tgaccagatg gtaattgtaa tagcgtcgcg
     2341 tgtgacggta ttacaattac acatcctgtc ccgtttttca ggccattata gcctgttatt
     2401 tttgtgcatc atagtcttat gcagacggca gaggcagggc gcagccctgc caggagtcat
     2461 tttttgatga taaaatcaga cttcaacatg aaacggagag aaagtgccaa tggcttctaa
     2521 aaaattttac tcagatgatg acatccagct ggcaaaagct gctttatcgg aattgccgga
     2581 cctcaccgct caacggaaaa cattgcgtga ttttcttgat gccattcgtg atgacatcat
     2641 tatcctggta aggacaaagg gttatacact ggcagatgtt cgtgacacgc tcaaaaatgc
     2701 agggtatgaa gtaggagaga aggcacttcg tgacattatt cgggaagcag aatcgaaaaa
     2761 aacatcccgc cgttcttcct ctaaaacagc acctaaaaag acagattcag gcaggaaaga
     2821 tggcatcgat atgaacaaca attgatgtga caatgtcaca tcgtgttctg agattatgat
     2881 gattacagaa aaaaaaagcc ccggcataaa taccagggct tttctgttta atcagactcg
     2941 tggcggcaat gcacc
//
LOCUS       DAPOXO010000202         2950 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.204, whole genome shotgun sequence.
ACCESSION   DAPOXO010000202 DAPOXO010000000
VERSION     DAPOXO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2950
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.204"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            89..1069
                     /gene="btuC"
                     /locus_tag="ROH59_005067"
     CDS             89..1069
                     /gene="btuC"
                     /locus_tag="ROH59_005067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HDX4807424.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     TPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPVNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR"
     gene            1132..1683
                     /gene="btuE"
                     /locus_tag="ROH59_005068"
     CDS             1132..1683
                     /gene="btuE"
                     /locus_tag="ROH59_005068"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HDX4807425.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKYAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWADRGFVVLGFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGLVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            1683..2432
                     /gene="btuD"
                     /locus_tag="ROH59_005069"
     CDS             1683..2432
                     /gene="btuD"
                     /locus_tag="ROH59_005069"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HDX4807426.1"
                     /translation="MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQNALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPANLAQAYGMNFRRLDIEGHRMLISTI"
     gene            2510..>2950
                     /locus_tag="ROH59_005070"
     CDS             2510..>2950
                     /locus_tag="ROH59_005070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDX4807427.1"
                     /translation="MRFCLILITALFLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKN"
BASE COUNT          664 a          703 c          832 g          751 t
ORIGIN      
        1 aaaaaggccg ctctgcggcc ttttttcttt tcactgtcga agagtcaccg taaaatcaac
       61 gccatgacac ttcagcagaa cggataccat gctgacactt gcccgccaac aacagcgaca
      121 aaatattcgc tggttattat gcctgtcagt tttgatgctg ctggcgcttc tcttaagcct
      181 ttgcgccggt gaacaatgga tctcgccagg tgactggttt actcctcgtg gcgaactgtt
      241 cgtctggcaa attcgcctgc cacgtacgct ggctgtattg ctggttggtg ctgcgttggc
      301 tatatccggc gctgtaatgc aggcgttgtt tgaaaatcct ctggcagaac ctggactact
      361 tggcgtctct aacggcgcag gcgtggggct tatcgccgcg gtattgcttg ggcaagggca
      421 actccccaac tgggcgctgg ggctgtgtgc gattgctggc gcgcttatca tcactttaat
      481 actcttacgt ttcgcccgtc gtcatctttc gaccagtcgg ttattgctgg ctggcgttgc
      541 attagggatt atctgtagtg cactaatgac gtgggctatc tacttttcca cctctgttga
      601 tttacgtcag ctgatgtact ggatgatggg cggttttggc ggcgtagact ggcggcaaag
      661 ctggctgatg ctggcattga tccccgtgtt gttgtggatc tgttgtcagt ccaggccggt
      721 gaatatgtta gcacttggcg agatctcggc gcggcaactg ggtttacccc tgtggttctg
      781 gcgcaatgtg ttggtcgcag cgaccggctg gatggttggc gtcagtgtgg cgctggcggg
      841 tgctatcggc tttattggtc tggtgatccc acatattctc cggctgtgtg gtttaaccga
      901 tcatcgcgta ttacttcccg gctgcgcgct ggcaggggcg agcgcattgc tgctggccga
      961 tattgtagcg cgcctggcat tagctgccgc agagctgcct attggcgtgg tcaccgcaac
     1021 gttgggtgcg ccggtgttta tctggttatt gttaaaagca ggacgttagc cgcaaaaaga
     1081 cggtctatga ttaaaagcta agatttttac tgaccacacc caggagaaac gatgcaagat
     1141 tccattctga cgaccgtagt gaaagatatc gacggtgaag tgaccacgct ggagaagtac
     1201 gccggtaatg tgctgttgat tgtcaatgtc gcctcaaagt gtggcttaac gccgcaatat
     1261 gagcagttgg agaatattca gaaagcctgg gccgatcgtg gttttgtggt gctgggattc
     1321 ccgtgcaacc agtttctgga acaagaaccg ggcagcgatg aagagattaa aacttactgt
     1381 accaccacat ggggggtgac gttcccgatg ttcagtaaga ttgaagttaa tggcgaagga
     1441 cgccatccgc tgtatcaaaa attgattgcc gcagcgccga ccgcagtcgc gccggaagag
     1501 agcggattct atgcccgtat ggtcagcaaa ggtcgtgcac cgctgtaccc tgatgatatt
     1561 ttatggaatt ttgagaaatt tttagttggc agggacggat tggtcatcca gcgtttttcc
     1621 ccggatatga cgccggaaga tcccattgtg atggaaagca ttaaactggc gttggcaaaa
     1681 taatgtctat tgtgatgcag ttacaggatg ttgcggaatc tacccgcctg gggccgcttt
     1741 ctggcgaggt tcgggctggg gagatcctgc acctggtggg gccgaacggc gcgggtaaga
     1801 gtaccttgct tgcacgaatg gccggaatga ccagcggtaa gggaagcatt cagttcgcgg
     1861 ggcaaccact ggaagcatgg tctgcaacaa aactcgcgct gcatcgcgcc tatctttcac
     1921 aacagcagac gccgccgttt gcaatgccgg tctggcacta cctgacactg catcagcacg
     1981 ataaaacgcg taccgaacta ctgaatgatg tcgcaggggc gctggctctt gatgacaaac
     2041 tcggacgtag caccaatcaa ctttccggcg gtgaatggca acgcgtacgt cttgctgcgg
     2101 tggtgcttca aatcacacca caagctaatc ccgcaggcca attgctgctt cttgatgagc
     2161 cgatgaacag tcttgatgtt gcgcaacaaa atgcgttaga caaaattctg agcgcgctgt
     2221 gtcagcaagg actggcgatt gtgatgagca gtcacgatct caaccacaca ttgcgtcatg
     2281 cgcatcgggc gtggttgcta aaaggtggaa aaatgctggc cagtggacgc agagaagagg
     2341 tgctcacgcc ggcaaatctg gcacaggcct atgggatgaa ttttcgccgt ctggatatcg
     2401 aaggtcacag aatgctgatt tcgaccatct gatttcatta gtatcttgaa aatcgggtaa
     2461 ttacgacgct aaattaatgc aagaataaaa aacagaggaa ccgtacggaa tgcgtttctg
     2521 ccttattttg atcacagcac tgtttctggc cgggtgtagc caccataaag caccgccgcc
     2581 aaatgccagg ctttctgatt cgatcaccgt tattgccggt ttgaacgacc agctacaaag
     2641 ctggcatggc acgccgtatc gttatggtgg catgacgcgg cgcggtgtgg actgttcggg
     2701 atttgtggtt gtgacgatgc gcgatcgttt cgatttgcag ctgccccgtg aaaccaaaca
     2761 acaagcctct attggcacgc aaattgataa agacgagttg ctgccaggtg acctggtctt
     2821 tttcaaaacg ggttccggac aaaatggttt gcatgtaggt atttacgata ccaacaacca
     2881 atttatccac gcctctacca gcaagggagt gatgcgttcc tcacttgata atgtctattg
     2941 gcagaaaaat
//
LOCUS       DAPOXO010000203         2943 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.205, whole genome shotgun sequence.
ACCESSION   DAPOXO010000203 DAPOXO010000000
VERSION     DAPOXO010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2943
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.205"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..57
                     /gene="yobI"
                     /locus_tag="ROH59_005071"
     CDS             <1..57
                     /gene="yobI"
                     /locus_tag="ROH59_005071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response small protein YobI"
                     /protein_id="HDX4807428.1"
                     /translation="FITHFFAEYVIFKYLLPI"
     gene            196..807
                     /gene="ruvA"
                     /locus_tag="ROH59_005072"
     CDS             196..807
                     /gene="ruvA"
                     /locus_tag="ROH59_005072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDX4807429.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
     gene            816..1826
                     /gene="ruvB"
                     /locus_tag="ROH59_005073"
     CDS             816..1826
                     /gene="ruvB"
                     /locus_tag="ROH59_005073"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDX4807430.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MS"
     gene            1936..2943
                     /locus_tag="ROH59_005074"
                     /pseudo
     CDS             1936..2943
                     /locus_tag="ROH59_005074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558234.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          741 a          693 c          786 g          723 t
ORIGIN      
        1 tttattacac atttcttcgc tgaatatgta atatttaaat atttgcttcc aatataacct
       61 gtagaataaa ttatactgcg ccatttttca gatcatcgag acacctcgca agttttcttc
      121 atccttcgct ggatatctat ccagcatttt tttatcatac agcattatct ttgattcatt
      181 acgcaggagc gtcatgtgat aggcagactc agaggcatca tcattgaaaa acaacccccg
      241 ctggtgttaa ttgaagtggg cggcgtaggc tatgaagtgc atatgccgat gacctgtttt
      301 tatgaactcc ctgaagcggg tcaggaagcg atcgttttca cccactttgt ggtgcgtgaa
      361 gacgcgcaac tgctgtacgg ttttaacaat aaacaagagc gcacgttgtt caaagagttg
      421 atcaaaacca acggcgtcgg cccgaagttg gcgctggcga tcctctccgg aatgtcagcg
      481 cagcagttcg ttaatgccgt tgagcgtgaa gaagtggggg cactggtgaa actgccgggt
      541 attggcaaaa aaaccgccga acgtttgatt gtcgaaatga aagaccgatt taaaggtttg
      601 catggcgatc tctttacgcc agccgccgac ctggtactca cgtctcctgc cagcccggcg
      661 accgacgatg ctgaacagga agcggttgct gcgctggtgg cactgggcta taaaccacaa
      721 gaagcaagcc gcatggtgag caaaatcgct cgccctgacg ccagcagtga aacattaatt
      781 cgcgaagccc tacgcgccgc gttatgaggt aaaggatgat tgaagcagac cgtctgattt
      841 ctgccggtac cactttgccg gaagatgtgg cagatcgcgc cattcgccct aaattactgg
      901 aagagtatgt tggtcagccg caggttcgtt cgcagatgga gattttcatc aaagcagcga
      961 aactgcgcgg cgatgccctc gatcatctat tgatttttgg tcctccgggg ttgggtaaaa
     1021 ctacgcttgc caatattgtc gccaatgaaa tgggcgttaa tttacgcacg acttctggtc
     1081 cggtgctgga aaaggcgggc gatctggcag caatgctcac taaccttgaa ccacacgatg
     1141 tactgtttat tgatgagatc caccgtcttt caccagtggt ggaagaggtg ttgtatccgg
     1201 caatggaaga ttaccaactg gatatcatga ttggtgaagg tccggcggca cgctccatta
     1261 aaattgattt gccgccgttt accctgattg gtgcaaccac gcgcgcaggt tcgctgacat
     1321 caccgttgcg cgatcgtttt ggtattgtgc aacgtctgga gttttatcag gtgccggatc
     1381 tgcaatatat cgtcagtcgc agcgcacgct ttatggggct tgagatgagt gatgacggcg
     1441 cgctggaagt tgctcgtcgt gcgcgcggta cgccacgtat tgccaaccgt ctgctgcgtc
     1501 gagtgcgtga tttcgccgaa gtgaagcacg atggcaccat ctcggcagat atcgctgctc
     1561 aggcgctgga tatgttgaat gtcgatgctg aaggtttcga ttatatggac cgcaaattgt
     1621 tgctggcggt aatcgataag ttctttggcg ggccggtagg tctggataac ctggcggcag
     1681 ccattggcga agaacgtgaa accattgagg atgtactgga accttatttg attcagcaag
     1741 gctttttgca gcgtacaccg cgtgggcgta tggcgacgac gcgggcgtgg aatcactttg
     1801 gcataacgcc gccagaaatg tcgtaagtcg gattggtcgc tcgtgccgca tccgacactg
     1861 gcagtgtgcc tgatgcgacg ctgttgaact gcaccccaaa tgttggacat aatctgacat
     1921 ctgaaggtgc agtttatgaa acattcattt gaagtaaaac ttgccgctgt aaatcattac
     1981 ctggctggtc atgcaggcat catttctacg gcaaaactct ttcaactttc tcacaccagc
     2041 ctctcacact ggattaatct ttttcttctt cacggtcctc gggcactgga ttgcagacac
     2101 aagcgtagct attctcctga agataaactt tgcgtggttc tttatgctct cgggcattct
     2161 gagtctctac cccgggtagc agcccggttt aacattccca gccacaacac ggttaaaaac
     2221 tggataaaag gctaccgcaa atctggtaat gaggccttta tcaggcgcag gaaggagaaa
     2281 agcatgaccc gttctgatga tacccatgaa aacgaggcaa acatgacgcc ggaagagatg
     2341 aagaatgagc tgcgttatct tcgcgcagaa aatgcatatc tgaaagccat gcaggagcat
     2401 cttctggaaa aaaagcgcca ggagctggag aaaaaacgaa agtcatccag agcctgaggt
     2461 acggacactg ccagtctgac ctgttaaagg ccgcagggct ggccagaagc acgctgtact
     2521 accagctgtc actgcagaag gctaaggaca agtatgctga tgtgaaacag ctcatagcct
     2581 ccatcttcca tgaacaccgg ggatgttatg ggtaccggcg gatccattgt gagcttcaga
     2641 aaagaggtct taagttcagt ggcaaaacgg tgcgaaaact gatgcaacag ctcggcctga
     2701 agtctcctgt gcgtctgaag aaataccggt cttaccgggg aaatatggga ctcgctgcag
     2761 aaaatatcct tcagcgactg ttcaaagcgg cagctccctg tgagaaatgg gtgacagata
     2821 tcaccgaatt cagggctggc ggacaaaaac tgtacctgtc cccgatactt gatttgttta
     2881 acggggaaat cgtggcgtgg gaaacggcct gcaggcctac agaggagctg gtgaagcgga
     2941 tgt
//
LOCUS       DAPOXO010000204         2914 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.206, whole genome shotgun sequence.
ACCESSION   DAPOXO010000204 DAPOXO010000000
VERSION     DAPOXO010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2914
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.206"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(81..1637)
                     /locus_tag="ROH59_005075"
     CDS             complement(81..1637)
                     /locus_tag="ROH59_005075"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDX4807431.1"
                     /translation="MTSIQQRAELHRQIWQIANDVRGSVDGWDFKQYVLGALFYRFIS
                     ENFSSYIEAGDDSICYAKLDDSVITDDIKDDAIKTKGYFIYPSQLFCNVAAKANTNDR
                     LNADLNSIFVAIESSAYGYPSEADIKGLFADFDTTSNRLGNTVKDKNARLAAVLKGVE
                     GLKLGDFNEHQIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSKLIAQLAMHGQTSV
                     NKIYDPAAGSGSLLLQAKKQFDNHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFD
                     IKLGNTLTEPHFRDEKPFDAIVSNPPYSVKWIGSDDPTLINDERFAPAGVLAPKSKAD
                     FAFVLHALNYLSAKGRAAIVCFPGIFYRGGAEQKIRQYLVDNNYVETVISLAPNLFFG
                     TTIAVNILVLSKHKTDTKVQFIDASELFKKETNNNILTDAHIEQIMQVFASKEDVAHL
                     AKSVAFETVVANDYNLSVSCYVEAKDNREIINIAELNAELKTTVSKIDQLRKDIDAIV
                     AEIEGCEVQK"
     gene            1820..2041
                     /locus_tag="ROH59_005076"
     CDS             1820..2041
                     /locus_tag="ROH59_005076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001603498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDX4807432.1"
                     /translation="MQSINFRTARGNLSEVLNNVEAGEEVEITRRGREPAVIVSKATF
                     EAYKKAALDAEFASLFDTLDSTNKELVNR"
     gene            2041..2421
                     /locus_tag="ROH59_005077"
     CDS             2041..2421
                     /locus_tag="ROH59_005077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDX4807433.1"
                     /translation="MRHISPEELIALHDANINRYGGLPGMSDPGRAEAIIGRVQARVA
                     YEEITDLFEVSATYLVATARGHIFNDANKRTALNSALLFLRRNGVQVFDSPELADLTV
                     GAATGEISVSSVADTLRRLYGSAE"
     gene            2426..2605
                     /locus_tag="ROH59_005078"
     CDS             2426..2605
                     /locus_tag="ROH59_005078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PdcA protein"
                     /protein_id="HDX4807434.1"
                     /translation="MARKYNKLSREALKMLLDGVSRREVKQYLAGKQIGARTAIAVLC
                     RQEMVVLKQRMPGSR"
     gene            2633..>2914
                     /locus_tag="ROH59_005079"
     CDS             2633..>2914
                     /locus_tag="ROH59_005079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pdcB"
                     /protein_id="HDX4807435.1"
                     /translation="MKAVITPFVQKELGVATFKVDQEVRKLVEAGRKFIMEPVPRELI
                     EHMDDGLVVSEQTMATNEALQPFFNSDELFRRIGGIDSLVAWLRRKEGQV"
BASE COUNT          763 a          665 c          708 g          778 t
ORIGIN      
        1 tatctttata gaaatatcct caagggtttt ccactcaacc tcaaccccat ccagcaattt
       61 ttccagataa ctcaactcgc tcatttctgc acctcgcagc cttcaatttc agccacaatc
      121 gcatcaatat ctttacgcaa ctggtcgatt ttgctgaccg tagttttaag ctctgcattt
      181 agctcagcaa tattgataat ttcgcggtta tctttcgctt ctacatagca gctcaccgac
      241 aggttatagt cattagcgac aacggtctca aacgcgacag atttcgccag atgagcaaca
      301 tcttccttgc tggcaaatac ctgcataatc tgttcgatat gggcatcggt caggatattg
      361 ttgttggtct cttttttgaa tagttcgctg gcatcaataa actgaacttt ggtatccgtt
      421 ttatgtttag acaacaccag aatattgacg gcaatggtgg tgccaaagaa caggttcggt
      481 gcgagtgaaa tcacggtttc gacatagtta ttgtcaacca gatactgacg gattttctgc
      541 tccgcgccgc cacggtaaaa aatgcccggg aagcagacaa tcgcagcacg acctttggca
      601 gaaagatagt tcagcgcatg taatacaaac gcaaagtcag ctttggattt gggggccaga
      661 acgccagccg gggcaaaacg ttcatcgtta atcagcgtcg ggtcatcgct gccaatccat
      721 ttcaccgaat acggcgggtt agaaacgatg gcatcaaacg gtttttcatc tctgaagtgc
      781 ggttcagtca gcgtattgcc cagcttgata tcaaacttgt cgtagttgat gttgtgcaaa
      841 aacatgttca tacgcgccag gttataggtc gtatggttga tttcctgacc aaaaaaacct
      901 tcttcgatga tatggttatc aaactgtttt ttcgcctgca acaacagtga gccggaaccc
      961 gctgccgggt cgtagatttt gttaacgctg gtctgcccgt gcatagccag ttgtgcaatc
     1021 agcttggaga cgtgctgcgg tgtaaagaac tcaccgcctg acttaccggc atttgccgca
     1081 tagttagaaa tcaggaactc ataggcatca ccgaacaggt caatctgatg ttcgttgaag
     1141 tcaccaagtt ttaacccttc aacccctttc agaaccgcag ccaggcgggc atttttatct
     1201 ttaacggtgt tacccaggcg gttactggtg gtatcgaaat cagcaaacaa acctttgatg
     1261 tcagcttctg aaggataacc gtaagcagaa ctttcgatag caacgaagat gctgtttaaa
     1321 tctgcattca atctgtcatt ggtatttgct ttcgcagcta cgttgcagaa aagctggctt
     1381 gggtagatga agtagccttt ggttttgatg gcatcgtctt taatgtcatc agtaattacg
     1441 ctgtcatcca gtttcgcata acagatactg tcatcaccgg cttcaatata actggaaaaa
     1501 ttttcgctga taaaacggta gaaaagtgcg cccagaacgt attgcttaaa atcccatcca
     1561 tcgaccgaac ccctgacatc gttagcaatt tgccagattt gacgatgaag ctctgcacgt
     1621 tgttgaatac ttgtcatttt catccactta tttcaggctt atgtaattgg cggtgattct
     1681 acagcaactt ggatgcttta gcagttcgga cattaggcta cgaatgacct gcctagaggt
     1741 ttgttaagcc gcaaagtgct ggtgctttat gcctgtgaag tttataattg tgtacacata
     1801 acgagtacac gaggtgttta tgcaatccat taacttccgt accgcgcgcg gcaacctttc
     1861 tgaagtgctc aacaatgttg aggccgggga agaggttgaa atcacccgca gaggccgtga
     1921 gccagcagta attgtcagca aggctacttt cgaagcctac aaaaaagcgg cgctggatgc
     1981 tgaatttgca tccctgtttg acaccctgga ctccaccaac aaggaactgg ttaaccgata
     2041 atgaggcata tatcaccgga agaacttatt gcgcttcatg atgcgaatat aaaccgctac
     2101 ggcggcctgc cgggaatgtc tgatccgggc agggcagagg ccattatcgg gagagttcag
     2161 gccagagttg cctacgaaga gatcaccgac cttttcgaag tctccgccac ctacctggtg
     2221 gctacagcga gagggcatat attcaatgat gccaataagc gtaccgcgct aaacagtgcg
     2281 ctgttatttc tacgccgtaa cggggtgcag gtatttgatt cacctgaact ggcagacctt
     2341 accgtagggg ctgcgaccgg agagatatct gtatcttctg tcgccgacac gttacgtaga
     2401 ttgtatggtt ctgcggagta gattaatggc acgcaaatac aacaaattgt cccgtgaagc
     2461 gttaaagatg cttcttgatg gcgtgagtcg ccgcgaggta aagcaatacc tggctggtaa
     2521 gcaaattggt gccaggaccg ctattgctgt gttatgccgt caggaaatgg ttgtgcttaa
     2581 acagagaatg ccgggcagca gataaagccc aatcagtgat gaaaggtgtg atgtgaaagc
     2641 cgtaattact ccctttgtac aaaaagagct tggcgtcgcc acattcaaag tggatcagga
     2701 agtcagaaag ctggtggagg ctggccgtaa atttattatg gagccggtac cgcgtgagtt
     2761 aatcgagcac atggacgacg gcctcgttgt ttccgagcaa actatggcaa caaatgaggc
     2821 gttgcagccg ttttttaaca gcgatgaact gtttcgccgt attggtggaa ttgactcgct
     2881 ggtagcgtgg ttgcgcagga aagaggggca ggtc
//
LOCUS       DAPOXO010000205         2769 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.207, whole genome shotgun sequence.
ACCESSION   DAPOXO010000205 DAPOXO010000000
VERSION     DAPOXO010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2769
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.207"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            37..2739
                     /gene="chiA"
                     /locus_tag="ROH59_005080"
     CDS             37..2739
                     /gene="chiA"
                     /locus_tag="ROH59_005080"
                     /EC_number="3.2.1.14"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chitinase/lysozyme"
                     /protein_id="HDX4807436.1"
                     /translation="MKLNIFTKSMIGMGLVCSSLPALAMEAWNNQQGGNKYQVIFDGK
                     IYENAWWVSSTNCPGKAKANDATNPWRLKRTATAAEISQFGNTLSCEKSGSSSSSTSN
                     TPASNTPANGGSATPAQGTVPSNSSVVAWNKQQGGQTWYVVFNGAVYKNAWWVASSNC
                     PGDAKGNDASNPWRYVRAATATEISETSNPQSCTSAPQPAPDVKPAPDVKPAPDVQPA
                     PADKSNDNYAVVAWKGQEGSSTWYVIYNGSIYKNAWWVGAANCPGDAKENDASNPWRY
                     VRAATATEITQYGNPGSCSVKPDNNGGAVTPVDPTPETPETPVTPTPDNNEPSTPADS
                     SNDYSLQAWSGQEGSEIYHVIFNGNVYQNAWWVGSEDCPRGTSVENSNNPWRLVRTAT
                     AAEMSQYGNPTTCEIDNGGVIIVDGFQASKAYSANSIVDYNDAHYKTSVDQDAWGFVP
                     GGDNPWKKYEPAKAWSASTVYVKGDRVVVDGQAYEALFWTQSDNPALVANQNATGSNS
                     RPWKPLGKTQSYSNEELNNAPQFNPETLYASDTLIRFNGENYISQSKVQKVSPSDSNP
                     WRVFVDWTGTKERVGTPKKAWPKHVYAPYVDFTLNTIPDLAALAKNHNVNHFTLAFVV
                     SKDANTCLPTWGTAYGMQNYAQYSKIKALREAGGDVMLSIGGANNAPLAASCKNVDDL
                     MQHYYDIVDNLNLRVLDFDIEGTWVADQASIERRNLAVKKVQDKWKSEGKDIAIWYTL
                     PILPTGLTPEGMNVLSDAKAKGVELAGVNVMTMDYGNAICQSANTEGQNIHGKCATSA
                     IANLHAQLKGLYGNKSDAEIDAMMGTTPMVGVNDVQGEVFYLSDARLVMQDAQKRNLG
                     MVGIWSIARDLPGGTNLSPEFHGLTKEQAPKYAFSEIFAPFTKQ"
BASE COUNT          735 a          649 c          730 g          655 t
ORIGIN      
        1 ttttgttttg cagtttttac gttacaaggg attataatga aattaaatat atttactaaa
       61 tctatgattg gtatggggct ggtgtgttcc tctctgccag cattggcaat ggaagcatgg
      121 aataatcaac aaggtggtaa taaatatcag gttattttcg atggcaaaat ttatgaaaat
      181 gcctggtggg tttcttctac aaattgcccg ggaaaagcga aagcaaatga tgcaactaac
      241 ccgtggcgtt taaagcgtac cgcaacagct gctgaaatta gtcagtttgg caatacactt
      301 tcctgcgaaa agagcggaag ctcatcttct tcaacttcaa atacgccagc atctaatacg
      361 cccgctaatg gcggttcggc tacaccagca cagggcactg ttccgtctaa ttcttctgta
      421 gttgcctgga ataaacagca gggcggtcaa acctggtatg tcgtctttaa tggtgcggta
      481 tataaaaatg cctggtgggt agcctcttct aactgcccgg gtgatgcgaa aggcaatgat
      541 gccagcaacc catggcgtta tgttcgtgcc gctacggcaa cggaaatctc agaaaccagt
      601 aatccacagt cttgtacttc agcaccacag cctgcaccgg atgtgaaacc ggcaccggac
      661 gttaaaccgg cccctgatgt tcagccagcc ccagctgata agtcaaacga caactatgct
      721 gttgtagcct ggaaaggtca ggaaggttct tctacatggt acgttatcta caacggcagc
      781 atttataaga acgcctggtg ggtaggcgcg gcaaattgcc caggcgatgc gaaagaaaac
      841 gatgccagca acccatggcg ttatgttcgc gcggcaacgg caacagaaat cactcagtat
      901 ggtaacccag gctcctgttc cgttaagccg gataataatg gcggtgctgt gactccggtt
      961 gatccaactc cggaaacacc ggaaactcca gttactccaa ctccggataa caacgagcca
     1021 tcaacaccag cggatagcag taacgattac tcactgcagg cgtggagtgg ccaggaaggc
     1081 agcgaaattt accatgttat cttcaatggt aatgtttatc agaatgcctg gtgggttggt
     1141 tctgaagatt gcccgcgtgg caccagtgta gaaaactcca ataacccatg gcgtctcgtg
     1201 cgtacagcta ccgctgcgga aatgagtcag tacggtaacc cgactacctg tgaaattgat
     1261 aatggcggcg tcattattgt ggatggtttc caggccagca aagcgtatag cgcgaacagc
     1321 atcgtagatt ataacgatgc acattataaa acctctgtcg atcaagacgc atggggcttt
     1381 gtccccggcg gcgataaccc gtggaagaaa tacgaaccgg cgaaagcatg gtccgcttcc
     1441 accgtgtacg tgaaaggtga tcgcgttgtt gttgatgggc aggcttatga agcgctgttc
     1501 tggacgcaaa gtgacaaccc tgctctggtt gcgaaccaaa acgccaccgg tagcaatagt
     1561 cgcccgtgga agccgttagg taagactcag agctatagca acgaagagct gaataatgcg
     1621 ccgcagttta atccagaaac gctttatgcc agtgatacgc tgattcgctt taacggtgag
     1681 aactacattt ctcagagtaa agtgcagaaa gtttctcctt ctgacagcaa cccgtggcgt
     1741 gtctttgttg actggaccgg aaccaaagag cgcgtaggta cgccgaagaa agcgtggccg
     1801 aaacacgttt atgcaccgta tgtcgacttt acgctgaata cgatcccgga tctggctgcg
     1861 ctggctaaga atcataacgt caaccacttc acgctggcgt ttgtggtgag taaagatgcg
     1921 aacacctgtc tgccgacatg ggggaccgct tacggtatgc agaattacgc tcagtacagc
     1981 aaaatcaaag cgctgcgtga ggctggcggt gatgtgatgc tgtctatcgg tggtgctaat
     2041 aatgccccgc tggcagcttc ctgtaagaac gttgacgatc taatgcagca ttattatgac
     2101 atcgttgata acctgaacct cagagtcctg gacttcgata tcgaaggcac ctgggttgcg
     2161 gatcaggcat ctattgaacg tcgtaacctt gctgtgaaga aagtgcagga taaatggaag
     2221 tcagaaggca aagatattgc tatctggtat accttgccaa ttctgccgac aggcctgacg
     2281 ccggaaggga tgaatgtcct gagcgatgcc aaagcgaaag gtgttgagct ggcgggtgtg
     2341 aacgtgatga caatggacta cggtaacgct atttgtcagt ctgcaaacac cgaaggccaa
     2401 aacatccacg gtaagtgtgc aacgtctgcg attgccaacc tgcatgcgca gctgaaaggc
     2461 ctctatggca ataagagtga tgcagaaatt gacgccatga tgggtaccac gccgatggtt
     2521 ggcgtgaacg acgttcaggg tgaggtgttc tatctctctg atgctcgtct ggtcatgcag
     2581 gatgcgcaga agcgtaatct cggtatggtt ggtatctggt caatcgcgcg cgacctgccg
     2641 ggcggcacta acctgtctcc ggaattccac ggtctgacta aagaacaggc tccgaagtac
     2701 gcatttagcg aaatcttcgc gccgtttact aagcaataaa tgtgttggcg ataccttccg
     2761 gtatcgccg
//
LOCUS       DAPOXO010000206         2685 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.208, whole genome shotgun sequence.
ACCESSION   DAPOXO010000206 DAPOXO010000000
VERSION     DAPOXO010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2685
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.208"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1970
                     /locus_tag="ROH59_005081"
     CDS             <1..1970
                     /locus_tag="ROH59_005081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001773871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HDX4807437.1"
                     /translation="AGSQAGTVRVTAKVQGKTFTLSIKQTATTEPDSEVSAVLTAAPA
                     EQVVGYNINLQLAVKDSQGNAITGDNTLSFYALNQAEGVEFGTVTEKDGVYSATVTSK
                     RAGKITIGVKSDSHDFSGVKKEITFIEDRQQVTFSQFEASQNNALADGKQRNMVTVSL
                     ADRFGNVVPGYAVTLSLPAGITQVGGEHAVSTDENGNAIFALISSTPGSYVITAHAGS
                     QMSTELTVTFASNMTGASLSLTPESSSLISNIPANGKDAAVLDVQLTNTNASVNGQKI
                     QLITSSEGLSVPTNIVTDSTGHVSVPLTTVKAGEYTVTARVTDGSHSVESGSVKLTFV
                     PDVASAELNMSVSKQEIVADGSENATVNIQLVDANNNAFTGEVDLTITPSTGASLTSS
                     NLQLDAHGQATTQFTASKSGQYTIQAEYVLDGKRITASQNIDAVTDVKGAVLEITSSA
                     SSAVVSDTNNLVFTLLLKSKSGEALSGRALNVKTSGPSKYGALVVDKTTVTTDENGQA
                     TVSVHGRTVGSYKLTATLNELGSDVSAVKSFSLYADDANGVLTLTKDPGYETNDGSPV
                     GIYARFVDHFGNPLSGTVEFSAGSEDSPDSQRVKMEPATVTLHWTGNAASEFSTYESG
                     YHWIKAKITNSKNTYEKTIRTYVVKLPEKDS"
     gene            complement(2007..>2685)
                     /locus_tag="ROH59_005082"
     CDS             complement(2007..>2685)
                     /locus_tag="ROH59_005082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX4807438.1"
                     /translation="YRTIPDTFPAPVEDGKAAIRYLREHASNYGIDPQRIGVLGDSAG
                     GWLAQMMGTTNGDKTFDKGDFLQQSSDVQAVATLYGISDLLNIGEGFPESVQEVHRSP
                     AVTEALMINGPAFRNFAGAPITASKEKALNASPIGHMKGVKPPFLIMHGSKDTLVSPE
                     QSAKLFRMLKKNGDNAEYVLVEGAEHGDKTWYQPIIINRVVEWFTKNLGAPIKTAPQQ
                     QNPNANL"
BASE COUNT          751 a          549 c          648 g          737 t
ORIGIN      
        1 ctgctggttc gcaggctggt acggtacgtg taactgcaaa agttcaggga aaaacattta
       61 ctctcagtat taagcaaaca gcaacaacag aacctgattc tgaggtcagt gctgttttaa
      121 ccgctgcacc agcagaacag gtagttggtt acaatatcaa tctacaactg gcagtgaagg
      181 attcacaagg aaatgcaatc actggtgata acactctgag cttttatgct cttaaccagg
      241 cagaaggagt cgagtttggg actgtaacgg aaaaagacgg tgtctatagc gcgacagtaa
      301 cttcaaaacg agctggtaag attactatcg gtgttaaatc tgatagtcat gatttctcag
      361 gtgttaagaa agaaatcacc tttattgagg accggcagca ggttacattc tctcagtttg
      421 aagccagcca aaataatgca ttggctgatg gaaaacagag aaatatggta actgtaagcc
      481 ttgcggaccg tttcggcaat gttgttcctg gttatgctgt cacattgtct ttaccagcag
      541 ggataactca agttggtggt gaacatgctg tttcaactga cgaaaatggt aatgctattt
      601 ttgcgttaat aagctccact ccggggtctt acgtgattac agctcatgct ggttctcaga
      661 tgtctactga gttaacagtg acctttgcat caaatatgac cggagcttca ctgtcactga
      721 cgcctgaaag cagtagttta atttccaata ttcctgctaa tggtaaggat gcagcggtat
      781 tagatgtgca gctgacaaat acgaatgcgt cggtcaatgg gcaaaagatt cagctcatca
      841 cctcatctga aggattatct gtaccaacaa atatcgtgac tgattcaaca gggcatgttt
      901 ctgttccgct tacaacggtg aaagctggtg agtacacggt gactgcacgg gtgactgacg
      961 gttcccatag cgtggaatct ggcagcgtta agttaacttt tgtgcccgat gttgcttctg
     1021 cagaactgaa tatgagtgta tcaaaacagg agattgtggc cgatggcagt gaaaacgcaa
     1081 cagtaaacat tcagttggtt gatgcgaata acaatgcgtt tacaggcgag gtggatttaa
     1141 cgattacacc atcgacggga gcatcattga ccagtagtaa tctgcaactg gatgctcatg
     1201 gacaggcaac aacgcagttc actgcatcga aatcaggcca gtacacaatt caggccgagt
     1261 atgttctgga tgggaaacgc ataaccgcaa gccagaatat tgatgccgtg acggatgtga
     1321 agggggctgt gttggagatc acatcatctg catcttcggc tgtagtgagc gataccaaca
     1381 atctggtatt tacgttactg ttgaaaagta agtcaggcga agcattaagt ggtcgagcat
     1441 tgaatgttaa gacatctggg ccgtctaaat atggtgcgtt ggtggttgat aaaaccacag
     1501 taacgactga tgagaacggt caggctacgg taagcgtaca tggtcgaacg gttggttcgt
     1561 ataaattaac ggcgacctta aacgaacttg gcagtgatgt tagcgcggtg aaatcattct
     1621 ccctgtacgc tgatgacgca aatggagtat tgactctaac aaaagatcct ggttatgaga
     1681 caaacgatgg atctccagta ggtatttatg ctcgatttgt cgatcatttt ggaaacccat
     1741 tatctggtac ggttgagttt tctgctggta gtgaagatag tccagactct caacgggtca
     1801 aaatggagcc tgctacagta acgttacact ggacaggtaa tgcagcttcg gaattcagca
     1861 cctatgaaag tggttatcac tggattaagg ccaaaataac gaatagcaaa aatacatatg
     1921 agaaaacaat aaggacttat gttgtaaaac tacctgaaaa ggatagttaa caaaattgaa
     1981 tggggagggc ttagccctcc ctctttttac aggttagcgt ttgggttttg ttgttgggga
     2041 gctgttttta taggcgctcc caggttttta gtaaaccact caacgactct gtttataata
     2101 attggctgat accatgtctt atcgccatgc tcggcccctt ctaccagcac gtactcagcg
     2161 ttatcaccgt tcttcttcaa catcctgaat agtttggcgc tttgctcagg tgaaaccaga
     2221 gtgtctttgc taccatgcat aataagaaat gggggtttta ctcctttcat atgtccgatt
     2281 ggactggcgt ttagcgcttt ttcttttgac gctgtgatgg gggctcccgc aaaatttctg
     2341 aatgcagggc cattgatcat taaggcttcg gttacggcag gagagcgatg aacctcctgc
     2401 actgattcag ggaacccctc gccaatattc aacaagtcag aaatcccata aagtgtggca
     2461 actgcctgaa catctgagga ttgctgaaga aagtcacctt tatcaaaggt tttgtcacca
     2521 tttgtagttc ccatcatctg ggcaagccat ccaccggcag agtcacccag aactccgatt
     2581 ctttgaggat caatcccata attgctggca tgctctctca ggtaacgtat tgcagctttt
     2641 ccatcctcaa ctggtgctgg aaatgtatca ggaattgttc tgtat
//
LOCUS       DAPOXO010000207         2614 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.209, whole genome shotgun sequence.
ACCESSION   DAPOXO010000207 DAPOXO010000000
VERSION     DAPOXO010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2614
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.209"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            85..642
                     /locus_tag="ROH59_005083"
     CDS             85..642
                     /locus_tag="ROH59_005083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4807439.1"
                     /translation="MAGVGFDGSSDISISAKNVNAFALRQTGNTVNGDTSVGWNWDSG
                     AYNAMIGGASALILHFNINAGSCPAVQFRVNYKNGGISYRSARDGYGFELGWSDFYTT
                     TRKPSAGDVGAYTRTECNSRFITGIRLGGLSSVQTWNGPGWSDRSGYVVTGSVNGNRD
                     ELIDTTQARPIQYCINGTWYNAGSI"
     gene            645..1178
                     /locus_tag="ROH59_005084"
     CDS             645..1178
                     /locus_tag="ROH59_005084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX4807440.1"
                     /translation="MMHLKNITAGNPKTKEQYQLTKQFNIKWLYSADGKNWYEEQKNF
                     QPDTLKMVYDHNGVIICIEKDVSAINPEGASVVELPDITANRRADISGKWMFKDGVVV
                     KRTYTEEEQRQQAENEKQSLLQLVRDKTQLWDSQLRLGIISDENKQKLTEWMLYAQKV
                     ESTDTSSLPVTFPEQPE"
     gene            complement(1207..1734)
                     /locus_tag="ROH59_005085"
     CDS             complement(1207..1734)
                     /locus_tag="ROH59_005085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001762409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX4807441.1"
                     /translation="MMHLKNIKAGNAKTLEQYELTKKHGVIWLYSEDGKNWYEEVKNF
                     QPDTIKIVYDENNIIVAITRDASTLNPEGFSVVEVPDITANRRTDDSGKWMFKDGAVV
                     KRIYTADEQQQQAESQKAALLSEAESVIQPLERAVRLNMATDEERTRLEAWERYSVLV
                     NRVDTANPEWPQKPE"
     gene            complement(1736..2521)
                     /locus_tag="ROH59_005086"
     CDS             complement(1736..2521)
                     /locus_tag="ROH59_005086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001468635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4807442.1"
                     /translation="MAFDGSSDITLKASHVGAFALGKTGSTVANDKAVGWNWSSGAYN
                     ANIGGASTLIIHFYMGDGSCPAAQFRINYKNGGIFYRSARDGYGFEADWSEFYTTTRK
                     PSAGDVGALPLSGGQLNGALGIGTSSALGGNSIVLGDNDTGFKQNGDGNLDVYANYVH
                     VMRFVPGSIQSNKTINITGRVNPSDYGNFDSRYVKDVRLGSQQYYGVNNWRTWNFQCP
                     SGHVLSGINVQDTGSNSADNIAGVYYRPVQKYINGTWYNVASV"
BASE COUNT          746 a          580 c          565 g          723 t
ORIGIN      
        1 aatcgacaaa cattcagcgg tggcctttct ggggaactgt ccggcaatgc cgctactgca
       61 acaaagctga aaacagcacg aaaaattgct ggagttggtt ttgatggttc tagcgatatt
      121 tcaattagtg ccaaaaatgt caatgcattt gcactccgac aaacaggtaa tactgttaat
      181 ggtgatacat ccgttggatg gaattgggat agtggtgcat ataacgccat gattggtggt
      241 gcatctgcat taattcttca ctttaatata aatgctggta gctgtcctgc cgtacaattc
      301 cgtgtgaatt ataaaaatgg tggcatttcc tacaggtcgg ctcgtgatgg ttatgggttt
      361 gaattaggtt ggtcagattt ctataccacg acacgaaaac cttcagcggg agatgttggt
      421 gcatatacgc ggacagaatg taactcaagg tttattacag gtattcgcct tggcggtctg
      481 tcatctgttc agacatggaa tggtcccggc tggtctgaca ggtcaggtta tgtcgttacg
      541 ggttcagtta acggaaaccg tgatgaatta attgatacaa cacaggcaag gccaattcag
      601 tattgcatta atgggacgtg gtataacgcg gggagtattt aacgatgatg cacttaaaaa
      661 acattactgc tggcaaccct aaaacaaaag agcaatacca gctaacaaag caatttaaca
      721 tcaaatggct ttattcagct gatggaaaaa actggtatga ggaacaaaag aatttccagc
      781 cagacacttt gaaaatggtc tatgaccata acggcgttat tatttgtatt gaaaaggatg
      841 tttcagcaat taatccggaa ggcgcaagcg tcgttgaatt acctgatatt acagcaaatc
      901 gccgggctga tatttcgggg aaatggatgt tcaaagatgg cgtagtggta aagcgaactt
      961 ataccgagga agagcagagg caacaagcgg aaaatgaaaa gcagagcctg ttgcaacttg
     1021 tcagggataa aactcagcta tgggactcac agctacggct gggcatcatt tccgacgaga
     1081 ataaacaaaa attaaccgag tggatgctct atgcgcagaa agtcgaatcc acagacacct
     1141 ccagcctgcc agtaacattt cccgaacaac ctgaatgaga caaggcccga taacgggcct
     1201 taatttttat tcaggctttt gtggccattc aggatttgcc gtatccacac ggttgaccag
     1261 aacactgtag cgttcccatg cttccagtcg tgtgcgttcc tcgtctgttg ccatattcag
     1321 cctgacagcg cgttccagcg gctggatgac tgattcagct tcggaaagca atgcggcctt
     1381 ttgtgattcg gcctgttgtt gctgttcgtc agccgtataa atccgtttaa ccacagctcc
     1441 gtccttaaac atccacttac cggaatcatc ggtccgacga ttggccgtta tatcgggaac
     1501 ctcgacgacg ctaaaacctt cgggattaag cgtggaggca tctctggtga tggcgacaat
     1561 aatattattt tcatcgtaaa caatctttat ggtgtctggc tgaaagtttt tcacttcctc
     1621 ataccagttt tttccgtcct cagagtaaag ccagataact ccgtgtttct ttgttaactc
     1681 atactgttcc agtgttttag cattacccgc ttttatgttc tttaagtgca tcatattaaa
     1741 cgctcgctac attataccag gtgccattta tatacttttg aacgggtctg taataaacac
     1801 ccgctatatt atcggcagag ttagaccctg tatcctgaac attaatacca gacaatacat
     1861 gacctgaagg gcactggaaa ttccatgttc gccagttgtt cactccataa tattgctgtg
     1921 aaccaagtcg aacatctttc acataacggg aatcaaagtt accgtaatcc gagggattaa
     1981 cacgccccgt aatatttatg gtcttattac tttgaatgct tccgggaaca aagcgcataa
     2041 catggacgta attagcataa acatccagat taccatcgcc attttgttta aagcccgtgt
     2101 cattatcacc caatacaatc gaattaccgc caagagcact ggatgttccg atacccagtg
     2161 caccattcag ttgaccacca gataacggca gtgcaccaac atctcctgct gaaggttttc
     2221 tggtggtggt gtaaaattcg gaccagtcgg cttcaaaacc ataaccatca cgggctgaac
     2281 gataaaaaat accgccattt ttataattaa tccgaaactg agctgcagga caacttccgt
     2341 ctcccatata aaaatgaata attaacgttg atgcaccacc aatatttgcg ttataggctc
     2401 cgctactcca gttccatcca actgctttat cattcgcaac ggtgcttcct gttttcccta
     2461 aggcaaacgc accaacatga cttgctttta atgtgatatc ggaggaacca tcaaaagcca
     2521 cattgcttat tttcctggca gtttttaatt ttgcagctgt agaagcattg ccggatagtt
     2581 caccagaaag gccaccgctg aatgtttgtc gatt
//
LOCUS       DAPOXO010000208         2599 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.210, whole genome shotgun sequence.
ACCESSION   DAPOXO010000208 DAPOXO010000000
VERSION     DAPOXO010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2599
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.210"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(22..690)
                     /locus_tag="ROH59_005087"
     CDS             complement(22..690)
                     /locus_tag="ROH59_005087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HDX4807443.1"
                     /translation="MRTTSFAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     TSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQGEGKDLNNESTPMAFENIKQVIDDMATDATMFD
                     VNKK"
     gene            complement(993..1586)
                     /gene="tehB"
                     /locus_tag="ROH59_005088"
     CDS             complement(993..1586)
                     /gene="tehB"
                     /locus_tag="ROH59_005088"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HDX4807444.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDGQYDFILST
                     VVLMFLEAKTIPGLIANMQRCAKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWEMVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            complement(1583..2575)
                     /gene="tehA"
                     /locus_tag="ROH59_005089"
     CDS             complement(1583..2575)
                     /gene="tehA"
                     /locus_tag="ROH59_005089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HDX4807445.1"
                     /translation="MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGL
                     VILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFR
                     PLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG
                     YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSV
                     NGGEGDTLAKMLFGYGLLQLLFMLCLMPWYLSQPFNASFWSFSFGVSALATTGLHLGS
                     GSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLVRTERAVLMKAEDKE"
BASE COUNT          717 a          665 c          567 g          650 t
ORIGIN      
        1 ctaacgatgg cgcgtctgga actacttttt gttaacgtca aacatggtgg catcggtcgc
       61 catgtcatca ataacttgtt taatattttc gaaagccatt ggcgtacttt cgttattcag
      121 gtctttacct tcgccctgac gaacgacttt gataaccggt ttattagtcg ctgcatcaat
      181 cagctcacct tcaaaataca agcgagtatc catggtacgg tggcctgtag ccatttgcgt
      241 ccccgcaacc actaatgcaa caggaaccac ttcatagaat tgcagccctt ctttgctggt
      301 atctacaccg gtaatggccc cacggaaaat cagactacgc ggcccagcgg tggtaaccag
      361 tggtttacgc tgcgctatcg cttctttcat ttcggtgttg gtatagttca aaattttatc
      421 cagaactttc tgccctacct gggtagaagg tttcggtacc ggataataag tgattgggtt
      481 ccagacgatg ctgtcatatt tgctttgatc aaaactcggg tctacccaac gtaaaacagg
      541 tttacctgtt gccgaggttg tttcttttaa atcagagtaa ttgtttaaaa aaccagaata
      601 tttatctggc tgggtgattt tagaggcaca accagacaga gccaacaagc cgcataaagc
      661 tgcaactttc gcaaatgatg tggtacgcat gaatagtttc ctgagatgat tatattactt
      721 tttaagttat agcaaaaagc gccgcttcgt gttgtggcaa aaaaagtgtt ggtgaaaata
      781 aattttttag ccccttttca gacgacatag tcaatgccga aaaaggggct aagtcaatca
      841 tcagtagtta aatttcagta cgttaagcgg ctaaaaaact tcgactactg tgattaattt
      901 cacatccctt cgataaaaaa tatgcttacc gaaaagaaga acagtaaacc atctcagcgt
      961 ggggaatttt cacgcgcttt gttcttaccg gatcattttt tacgtgccag catcgtggcg
     1021 aaacgcagtt taatacgatt accgttggcg tcggtgcggt gcagctcgcc gacgtcttca
     1081 ttgtatttca ccatctccca gccttcgtaa tatcgacgta attccccctc tttgaaggca
     1141 aacgggaagc cgacggtaca tggataatca gcggtatcca tcgccgccac aatcaggttg
     1201 taaccgccag gtttagcgca acgttgcata ttggcaatca gccctgggat ggttttagcc
     1261 tcaaggaaca tcagcaccac agtcgaaaga ataaaatcgt actgtccatc aaatgtgagg
     1321 ttattcagat caacgacccg ggtgtgtaaa ttatccagat tttcaatgga cttaatgcgc
     1381 tcgacgttgg cgatactcat ggcattttta tcccatgcgt caacatcata accattggct
     1441 gccaggtaaa gactgttacg accattgcca cagcccagat ccagcgtttt acccggttta
     1501 accactttca ccgcttccag cacttcagag tgtgtgcggg ttaattcata tttatcagta
     1561 aaatagtttt catcacgaat gatcattctt tgtcctctgc tttcattaaa acggcgcgct
     1621 cggttctgac taacaatttt ccctgcatca gaagcgcaaa agtacggatg agcagtattg
     1681 caataataaa attggtaaag ataaacagcg gcaccgccag cgtatggaaa aatccattat
     1741 cgctgccact ccccagatgc aaaccggtgg ttgccagtgc agatacgccg aacgagaaac
     1801 tccagaatga agcattaaat ggctgggaga gataccatgg catcagacat agcataaaca
     1861 gcagttgcag cagtccataa ccgaaaagca ttttcgccag cgtgtcaccc tcgccgccgt
     1921 tgacgctcag ccaggcacta caggccacca gcgcaggagc gagctgaatg ccgagtgatg
     1981 tcctcagtgc cgtgggtaat tctcccgaac tgcgcagacg ctgcaagatc accggttcca
     2041 ggcttagcca tgagaaaacg cctgcgccta aaaacaccag accggcgtcg gtgtagccca
     2101 acgcaccaca ggccattgcg ctgataaagt tgttggcaac tgtcggcaga tacagtccag
     2161 gcgtggtagc ttcttcaggg tgagatccac gccataatcc cgcagtttgc caggcggcat
     2221 aagccaactg aaccacgaca ccaaaactga acaggcacac cgccagtggg cgaaaccacg
     2281 gaacaaaacc aatcgccacc agcatcgtcg ttgccggaaa caaactcaca aaactgctca
     2341 gcactggatg gcgcacttct gccagcacgc tatgcggaaa gcgtatgagt cgggtaataa
     2401 atgcgccagt caataatccc cagatgatca tcgccagaat caccagccca tcccccaacc
     2461 agtggctgac ctgccaaacc tggctggcat agcgccaggc aaatcccatc cctatcgtcc
     2521 ccaacacaat accaaagtag cctgccggca aattgagcac tttatcgctc tgcatcttct
     2581 tactcatttt gtttaattt
//
LOCUS       DAPOXO010000209         2561 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.211, whole genome shotgun sequence.
ACCESSION   DAPOXO010000209 DAPOXO010000000
VERSION     DAPOXO010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2561
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.211"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            58..1251
                     /locus_tag="ROH59_005090"
     CDS             58..1251
                     /locus_tag="ROH59_005090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDX4807446.1"
                     /translation="MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVAFRLRSEVLSVAKDDTGFTLELNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGTVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQTLISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLVAE"
     gene            complement(1338..2390)
                     /locus_tag="ROH59_005091"
     CDS             complement(1338..2390)
                     /locus_tag="ROH59_005091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 family protein"
                     /protein_id="HDX4807447.1"
                     /translation="MNIYIGWLFKLIPLLMGIICIALGEFVLTGSGQSEYFVAGHVLI
                     SLSAICLALFTTAFIIISQLTHGMNKFYNKLFPVIGYAGSATTMIWGWSLLASNNVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNASGSKSDGTPLQAYSSTIGNCLI
                     AVPVLLTLFGFIWSVILLRSADITPHYVAGHVLMGLTAICACLIGLVATIVHQTRNTF
                     SVKEHWLWCYWVILLGSLTIIFGIYVLISSDASARLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLAAFLAEIAQTDMAYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
BASE COUNT          740 a          595 c          626 g          600 t
ORIGIN      
        1 tgcgaccact gaggaatctt tacaattcac gcccgttttt tcttagagga gcgcaacgtg
       61 gaaaggtttg atgccattat tataggcgct ggtgcggcag gtatgttctg ttctgcgctg
      121 gcaggtcagg caggacgccg ggttctgctg atcgataatg gtaaaaaacc agggcgcaaa
      181 atcctcatgt ctggcggtgg gcgctgcaac tttaccaacc tttatgtcga accaggcgct
      241 tatctgagcc agaatccgca tttttgtaag tctgcactcg cgcgttttac ccagtgggat
      301 ttcattgatc tggtcaataa acacggcatc gcctggcacg agaaaacgtt agggcagctc
      361 ttctgcgatg actccgcgca gcagattgtc gacatgctgg tggatgagtg cgagaagggc
      421 aatgtggcct tcagattgcg tagcgaagtg ctgagcgtgg cgaaggatga tacaggcttc
      481 acgcttgaac tgaacggcat gactgtcggt tgcgaaaagc tggtcattgc gaccggtgga
      541 ctgtcaatgc cggggctggg cgcatcgccg tttggttata agattgccga acaattcggc
      601 ctcaacgtgc tgccgacccg tgcgggtctg gtgccattca ctctgcataa accgttgctt
      661 gaagagttac aggtgctggc gggcgtggct gtgccttccg tgattaccgc tgaaaacggt
      721 accgttttcc gtgagaactt actcttcacc caccgcggct tatctggacc ggcggtgttg
      781 cagatttcca gctactggca accgggtgaa tttgtcagca tcaatctgct accggatgtg
      841 gacctcgaaa ccttcctgaa tgagcagcgt aatgcacatc cgaatcaaag cctgaaaaac
      901 acgctggcgg ttcatctgcc gaagcggttg gttgaacggt tacaacaact cgggcaaatc
      961 ccggatgtct cgctaaaaca gctcaacgtg cgtgaccaac agacactgat tagcacattg
     1021 actgactggc gcgtacaacc caacggcact gaaggctatc gcactgccga agtgacgctc
     1081 ggcggcgtgg acaccaacga actctcttca cggacgatgg aagcgcgcaa agtgcctggg
     1141 ctgtacttca tcggcgaagt gatggacgtc accggctggc tggggggcta taacttccag
     1201 tgggcgtggt cgagtgcatg ggcttgtgcg caggatttgg tggcagaata agaagcaaaa
     1261 tgcgctctcg ataccagagg gattaacctg aataaaacca gataaggcgc tcaacgcctt
     1321 atctgaagcc ttttttatta ttttttcgct gaacccgctt ctaatataga aacgatggaa
     1381 aacagtgtaa aacaaactgc acctaagcca accagaactc gcgaaggaat aaagtaagcc
     1441 atatcggttt gcgcaatttc agccaggaac gcagcaagga acagacaaaa cagacaggta
     1501 aataccggaa tcatgggtat tctgttggct aacgaacagg tgcgtcgcca taccagcgct
     1561 aacaaccaca ctttggagaa aatactgtag cagatcatcc ccaggcaaat gagaataatg
     1621 ccgggggcca ggcgggcgct tgcatctgaa ctgattaata cgtagatacc aaaaataatg
     1681 gtaagtgagc caagcaaaat aacccaatag caccacagcc aatgttcttt cactgagaac
     1741 gtattccgcg tttgatggac aatagtggcg acaaggccaa taagacaagc gcaaattgcc
     1801 gttaacccca ttagtacgtg acctgcaaca taatgtggtg tgatatctgc actacgtaac
     1861 agtatgactg accaaatgaa accaaagaga gtaagcagaa cgggaacggc aattaaacaa
     1921 ttaccgattg ttgaagaata ggcctgcaat ggcgtaccgt cactcttact gcccgaggcg
     1981 tttttgggga tcaacagaaa atgtccggaa gatgccgcta cggttgatac acaagcggca
     2041 atcatgccaa cgccgaaaat aacatgaccg gcgacaaatt catctgccat cacattattg
     2101 cttgccaaca gtgaccatcc ccaaatcata gttgtagcag aaccggcata accaataaca
     2161 ggaaataact tgttgtagaa tttattcatg ccgtgagtta actgagatat aataataaat
     2221 gcggtagtga acaatgccag acatatcgca gaaagagaaa tcagaacatg ccctgcaacg
     2281 aaatattcac tttgcccaga accggttaat acaaactcac ctaatgcgat gcatattata
     2341 cccatcagta aaggaattaa tttaaacaac catccgatat atatattcat tttaaacccc
     2401 atatatattt tctgctacac ttcgaaaaac atatgattcg tcttttcagt tagttaaata
     2461 tgtctataag atgccatcaa ttaaaaaaag taacttcact ataatcggat ttagcgttat
     2521 ggggatcaac ttttagcggt gagttaatgc tattaaataa a
//
LOCUS       DAPOXO010000210         2528 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.212, whole genome shotgun sequence.
ACCESSION   DAPOXO010000210 DAPOXO010000000
VERSION     DAPOXO010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2528
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.212"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..854
                     /gene="rfaJ"
                     /locus_tag="ROH59_005092"
     CDS             <1..854
                     /gene="rfaJ"
                     /locus_tag="ROH59_005092"
                     /EC_number="2.4.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase RfaJ"
                     /protein_id="HDX4807448.1"
                     /translation="INLDFYIIADVYNDAFFQKVAKLAEQYQLRITLYRINTDKLQCL
                     PCTQVWSRAMYFRLFAFQLLGLTLDRLLYLDADVVCKGDISQLLHLDLNGAVAAVVKD
                     VDPMQEKAASRLSDPELLGQYFNSGVVYLDLKKWANAKLTEKALSILMSKDNVYKYPD
                     QDVMNVLLKGMTIFLPRGYNTIYTIKSELKDKTHQNYKKLIIENTLLIHYTGATKPWH
                     KWAIYPSTKYYKIALDNSPWKDDSPRDAKSIIEFKKRYKHLLVQHHYISGIIAGVCYL
                     CRKYYPK"
     gene            872..1570
                     /gene="rfaY"
                     /locus_tag="ROH59_005093"
     CDS             872..1570
                     /gene="rfaY"
                     /locus_tag="ROH59_005093"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HDX4807449.1"
                     /translation="MIQKSKIKDLVVFTDEENSKYLNVLNDFLSYNINIIKVFRSIDD
                     TKVMLIDTDYGKLILKVFSPKVKRNERFFKSLLKGDYYERLFVQTQKVRNEGLNTLND
                     FYLLAERKTLRFVHTYIMIIEYIDGIELCDMPDIDDSLKNKIQQSINALHKHGMVSGD
                     PHRGNFIIKNGEVRIIDLSGKRASAQRKAKDRIDLERHYGIKNEIKDLGYYLLVYRKK
                     MRNFMRRLKGKPAR"
     gene            1640..2491
                     /gene="waaZ"
                     /locus_tag="ROH59_005094"
     CDS             1640..2491
                     /gene="waaZ"
                     /locus_tag="ROH59_005094"
                     /EC_number="2.4.99.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-oct-2-ulosonate III transferase
                     WaaZ"
                     /protein_id="HDX4807450.1"
                     /translation="MKNIRYIDKKDVENLIENKTSDDVIIFLSGPTSQKTPLSVLRTK
                     DIIAVNGSVQYLLSHNIVPFIYVLTDVRFLHQRRDDFYKFSQRSRYTIVNVDVYEHAS
                     KEDKLYILQNCLVLRSFYRREKGGFIKKIKFNILSQIHKELLISVPLSKKGRLVGFCK
                     DISFGYCSCHTIAFAAIQIAYSLKYARIICSGLDLTGNCSRFYDENNNPMPSELSKDL
                     FKILPFFRFMRDNVEDINIYNLSDDTAISYDVIPFIKFQDISREESKDKTRKKMQYRT
                     STDSYAN"
BASE COUNT          848 a          401 c          439 g          840 t
ORIGIN      
        1 atattaatct tgatttttat attattgctg atgtttataa tgatgctttt ttccaaaaag
       61 ttgcaaagct tgcagagcaa taccaattaa gaatcacatt atatagaatt aacactgata
      121 agctccagtg cttgccttgt acacaggtct ggtcaagagc aatgtacttc cgtttatttg
      181 catttcaatt attgggttta acacttgatc gtttgcttta tcttgatgca gatgttgttt
      241 gtaaaggcga tattagccaa ctattgcatc tggatttaaa cggcgcggtt gctgctgttg
      301 ttaaagatgt tgacccaatg caggaaaagg cggcatccag gttgtctgat ccagaattac
      361 tcgggcagta ctttaattcc ggtgtcgttt atttagattt aaaaaaatgg gctaacgcaa
      421 aactaacaga aaaagcgttg tctattctta tgagtaaaga taatgtgtat aaataccctg
      481 atcaagatgt tatgaatgtc ttactgaaag ggatgacaat atttttgcct cgtggatata
      541 atacaattta tacaattaaa agtgaattaa aagacaaaac acatcaaaac tataaaaagc
      601 tgattataga aaatactctt cttattcatt atacaggtgc aactaaaccg tggcacaaat
      661 gggcaattta tccatcgaca aaatactata aaatagcttt agacaattcc ccctggaaag
      721 atgactctcc acgagatgcg aaatcaatta ttgaattcaa aaaaagatat aaacatcttt
      781 tagtgcaaca tcactatatc tcaggaatta tagcaggagt ctgttatctt tgccgaaaat
      841 attaccctaa ataacattta actggtttgt tatgattcag aagagcaaga tcaaagactt
      901 ggttgttttt accgatgaag agaattcaaa gtacctcaat gtattaaatg acttcttgtc
      961 ttataatata aatatcatca aggtttttcg ttctattgat gatacaaaag ttatgcttat
     1021 tgataccgat tacggtaaat tgattcttaa ggttttttct ccgaaagtta agcgtaacga
     1081 acgtttcttt aagtctctgt taaaaggtga ttattacgaa cgcctttttg tgcaaactca
     1141 aaaagtacga aatgaagggt taaatacact caatgatttt tatttattgg ctgaacggaa
     1201 aaccttacga tttgtccata cttatatcat gatcatcgag tatattgatg gtatagagtt
     1261 atgtgatatg cccgatattg atgattcgct aaaaaataaa attcaacaat caattaatgc
     1321 cttgcataaa catggcatgg tttctggcga ccctcatcgt ggtaacttca ttataaaaaa
     1381 tggtgaggtc cgaattattg atctctctgg aaaacgtgct tcagcgcagc gtaaagcgaa
     1441 agatcgcatt gacttagagc gtcattacgg tattaaaaat gagattaaag atctaggcta
     1501 ttatctttta gtatatcgta aaaaaatgcg caattttatg cggcgtttga aagggaaacc
     1561 agctcgctaa aaaaatccca caattacatg tcttcaccag gacagtttta agcggagtta
     1621 tttatttcac aggtttatca tgaagaatat tagatatatt gacaaaaaag atgttgaaaa
     1681 cctgattgaa aataaaacat ctgatgatgt tattattttt ctttcgggcc ctacatcgca
     1741 aaaaacacct ttgtcagtat tacgaacaaa ggatattatt gctgtcaatg gttctgtgca
     1801 atatctgtta agtcataata tcgttccttt tatatatgta cttacagatg tccgcttttt
     1861 acatcagcgt cgtgatgatt tttataaatt tagccagaga agccgttata ccatagtaaa
     1921 cgttgacgtt tatgaacatg cttccaaaga agataaactt tatatcctcc agaactgcct
     1981 cgtattacgg tccttttatc gccgggaaaa aggtggtttt ataaagaaga ttaaatttaa
     2041 tatattgagt cagattcaca aagaactgct gatctctgta ccgttgtcta aaaaaggtcg
     2101 tctggttgga ttttgcaagg acattagttt tggttattgt tcatgccata ctattgcctt
     2161 tgctgcaatt caaatagcat attcacttaa gtatgcacgg attatttgtt ctggtcttga
     2221 tttaacgggt aactgctctc gtttctatga cgaaaataat aatcccatgc cctcggaatt
     2281 gagtaaggat ttattcaaaa tcttgccatt tttccgtttt atgcgtgata atgtagaaga
     2341 tattaatatc tataatttat cagatgatac agctatttct tacgatgtaa ttccatttat
     2401 taaatttcaa gatatcagta gagaagaatc aaaagataag acaagaaaaa aaatgcaata
     2461 tagaacttca actgattctt atgctaatta atcatcctga aactaaagta atatggtata
     2521 aaaatgcg
//
LOCUS       DAPOXO010000211         2514 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.213, whole genome shotgun sequence.
ACCESSION   DAPOXO010000211 DAPOXO010000000
VERSION     DAPOXO010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2514
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.213"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            158..1699
                     /gene="istA"
                     /locus_tag="ROH59_005095"
     CDS             158..1699
                     /gene="istA"
                     /locus_tag="ROH59_005095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family transposase"
                     /protein_id="HDX4807451.1"
                     /translation="MPTVPISMRKLKEILRLKYGVGLSHRQIGRSLAISPSVVSRYAN
                     RAAQLGIKQWPLPTGWDDTKLKHAFLQTQVKMKKHSLPDWATVHRELRNKCVTLQLLW
                     EEYCERNPGGFYSYNHYCRMYREWLKTTSPSMRQVHKAGEKLFVDYCGPTVGVTDPET
                     GEIRTAQVIVAVLGASSYTWAEATWSQQLEDWVMSHVRCFQWLGGVPELVVPDNLKSA
                     TSRACKYDPDVNPTYQQMLEHYNVAVLPARPRKPKDKAKAEVGVQVVERWIMARIRHE
                     IFYSLASLNQRIRELLERLNNKIMQKLGYSRAELFIQLDKPALKPLPEASYSYTLVKK
                     VRVHADYHVEIDKHYYSVPCSLLGQQLEAWISGELVRLFNQGQEVAVHPRKRTYGYST
                     RNEHMPEAHRQHATWTPERLLEWAGHIGSETHSYVLHILNSRPHPEQSYRFCLGLLNL
                     HKKYSKARLNAACARALKTKVWRLSGIKSILEKGLDKQPVQDPKPDLLSTMEHENVRG
                     SEYYH"
     gene            1714..2460
                     /gene="istB"
                     /locus_tag="ROH59_005096"
     CDS             1714..2460
                     /gene="istB"
                     /locus_tag="ROH59_005096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family helper ATPase
                     IstB"
                     /protein_id="HDX4807452.1"
                     /translation="MNHLYEQLTALKLTGFRDALKKQLAQPGTYQELGFEERLSLLTA
                     EELTCRENRKAERLIKHARFRLNAELSKLDYRNNRGLDRALIRSLSQGNWLTLKQNIL
                     LTGATGSGKTFLACALGHNACRQGYKVYYYRLKALMEQCYQGHADGRYSKLLTRLNNS
                     DLLLLDDWGLEPLSSEQRSDLLEIVDLMYQRGSIIVVSQLPVENWYKMIGDSTHADAI
                     LDRLVHGSIKIELKGESMRKIQSPLTEGDQ"
BASE COUNT          718 a          590 c          605 g          601 t
ORIGIN      
        1 ccatcgagat cgggtaataa catttgaaca gatcgctgaa taacatcgat ggagatcact
       61 tttgactcat tttgttattc agtgatctcc atcaatgtta ttggaacttc acaggtgtgt
      121 tgatctgtat cttttgccat tccggtaaag gatacctatg ccaacagttc caatttctat
      181 gagaaaactt aaagaaattc ttaggcttaa atacggtgtt ggactcagcc atcgacaaat
      241 tggtcgtagt cttgcaatct ccccttccgt tgtatccaga tatgctaatc gggcggctca
      301 acttggcata aagcagtggc ccttacctac aggatgggat gatacaaaac taaaacatgc
      361 gttccttcag acccaggtta agatgaagaa gcactctctg cctgactggg ctacagtaca
      421 ccgggaactg cgtaataaat gcgtgacgct gcagctactc tgggaagaat actgtgagcg
      481 taatccaggc ggtttttaca gctataacca ttactgccgg atgtaccgtg aatggctcaa
      541 aaccacttca ccatcaatgc gtcaggtaca taaagctggc gaaaaacttt tcgttgatta
      601 ctgtggacct accgttggcg ttaccgaccc tgagaccgga gaaataagaa ctgctcaggt
      661 catcgtagct gttctcgggg catcaagtta cacatgggca gaggccacct ggtctcagca
      721 gcttgaagac tgggtgatga gtcatgttcg ctgcttccag tggttgggtg gcgttcctga
      781 acttgttgtt ccggacaatc tgaaaagcgc cacatccagg gcatgtaagt atgatcctga
      841 cgttaaccct acctaccagc agatgcttga gcattataat gtcgcagttt tgcctgcgcg
      901 gccacgtaaa ccgaaagata aagccaaagc tgaagttggc gttcaggttg ttgaacgctg
      961 gatcatggcc cgaatcaggc atgagatctt ctacagcctt gcatcgctta atcagcgcat
     1021 tcgggagttg ctggaaagac tgaataacaa aataatgcag aagttgggtt attcacgtgc
     1081 agaactcttc atccagcttg ataaacccgc actgaagcct cttcctgaag ccagttacag
     1141 ttacaccctg gtgaagaaag tcagagttca tgccgattac cacgtggaaa tcgacaaaca
     1201 ttactactcg gttccatgtt cgctgttagg ccagcaactg gaagcatgga tctccggaga
     1261 actggtaaga ctcttcaatc aggggcagga ggttgctgtg cacccgcgca agcgtactta
     1321 tggctacagt acccgcaacg agcacatgcc tgaagctcat cgacagcatg ccacctggac
     1381 gccagagcgt cttctggaat gggcggggca cataggcagt gaaactcata gttatgtgct
     1441 tcatatactg aactctcgtc cacatccgga acaaagctat cgcttctgcc ttggactcct
     1501 gaaccttcat aaaaaataca gtaaagccag acttaatgca gcatgtgcaa gagctctgaa
     1561 aacaaaggta tggcgtctgt caggtattaa atcgatcctg gaaaaaggtc tggataaaca
     1621 acctgttcag gatccaaaac cagatctgtt atccacgatg gaacacgaaa acgtacgcgg
     1681 cagtgagtat taccactgat acgggatcca atgatgaatc atctttacga acaactgacc
     1741 gcacttaaac tcaccggctt ccgtgatgcg cttaaaaagc aacttgctca accgggcaca
     1801 taccaggagc tgggcttcga agaacgcctg tcattactga cagcagaaga actaacctgc
     1861 cgtgaaaaca ggaaggcaga gcgtctgatc aaacatgcac ggttcagact taatgctgag
     1921 ttatcaaagc tggattatcg taacaataga gggctggaca gggccctcat ccgttcactc
     1981 agtcagggaa actggttaac cctgaaacaa aatattttac tgaccggggc caccggcagc
     2041 ggtaaaacgt tcctggcatg tgcacttggt cataatgcct gccgacaggg atacaaggtc
     2101 tactattatc gccttaaagc gctgatggaa cagtgctatc aggggcatgc tgatggaaga
     2161 tacagcaaac ttttgaccag gctgaataat agcgatctgc tgcttctgga tgactggggg
     2221 ctggaacctc tctcatcaga acagcgtagc gacctgctgg aaatagtgga tctgatgtac
     2281 caacgaggct caatcatcgt agtgagccag ttgccggtgg aaaactggta caaaatgatc
     2341 ggagactcca cacatgcgga tgccatccta gatcgactgg ttcatggcag tatcaagatc
     2401 gaacttaaag gagaatcaat gcggaaaata caatctccgt tgaccgaagg agatcagtga
     2461 aggtaattta aaaacggttc tgtgaaagtg acacgaaccg atctccatcg atgt
//
LOCUS       DAPOXO010000212         2470 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.214, whole genome shotgun sequence.
ACCESSION   DAPOXO010000212 DAPOXO010000000
VERSION     DAPOXO010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2470
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.214"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            53..478
                     /locus_tag="ROH59_005097"
     CDS             53..478
                     /locus_tag="ROH59_005097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX4807453.1"
                     /translation="MELQDWRKEPRKNYSNEFKLRMVELASQPGACVAQIARENGVND
                     NVIFKWLRLWQNEGRVSRRLPVTTSSDTGVELLPVEITPDEQKEPVAAIAPSLSTSTQ
                     TRVSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
     gene            475..825
                     /gene="tnpB"
                     /locus_tag="ROH59_005098"
     CDS             475..825
                     /gene="tnpB"
                     /locus_tag="ROH59_005098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX4807454.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLF
                     IFRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPAVRDGKVSITRSQLAMLLDKLDW
                     RQPKTSSRNSLTML"
     gene            856..2469
                     /locus_tag="ROH59_005099"
     CDS             856..2469
                     /locus_tag="ROH59_005099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc23 family transposase"
                     /protein_id="HDX4807455.1"
                     /translation="MSQKYLIRIAELERLLSEQAEALRQKDQQLSLVEETEAFLRSAL
                     TRAEEKIEEDEREIEHLRAQIEKLRRMLFGTRSEKLRREVELAEALLKQREQDSDRYS
                     GREDDPQVPRQLRQSRHRRPLPAHLPREIHRLEPEESCCPECGGELDYLGEVSAEQLE
                     LVSSALKVIRTERVKKACTKCDCIVEAPAPSRPIERGIAGPGLLARVLTGKYCEHLPL
                     YRQSEIFARQGVELSRALLSNWVDACCQLMTPVNDALYRYVMNTRKVHTDDTPVKVLA
                     PGQKKAKTGRIWTYVRDDRNVGSSSPPAVWFAYSPNRQGKHPEQHLRPFRGILQADAF
                     TGYDRLFSAEREGGALTEVACWAHARRKIHDVYISSKSATAEEALKRISELYAIEDEI
                     RGLPESERLAVRQQRSKVLLTSLHEWMVEKNGTLSKKSRLGEAFSYVLNQWDALCYYS
                     DDGLAEADNNAAERALRAVCLGKKNFMFFGSDHGGERGALLYGLIGTCRLNGIDPEAY
                     LRHILSVLPEWPSNRVDELLPWNVVLTNK"
BASE COUNT          633 a          615 c          694 g          528 t
ORIGIN      
        1 agacgagaat tggtaactta gacgcccatc tgatatagac ggacatctaa gtatggaatt
       61 acaggactgg cgaaaagaac ctcgtaaaaa ctattcgaat gaattcaaac ttcgtatggt
      121 ggaactggca tcacaacctg gagcttgtgt tgcacagatt gcacgtgaaa atggcgtcaa
      181 tgataatgtt attttcaaat ggctcaggct ctggcagaac gaagggcgtg tttcgcggcg
      241 tcttccggta acgacctctt ctgacactgg cgttgaatta ttacctgtag aaataacgcc
      301 ggatgagcag aaagaacctg tggcggccat tgcgccgtct ttatccactt ccactcagac
      361 cagagtcagt gccagttcct gcaaggtgga attccgtcac ggtaacatga cgctggaaaa
      421 tccatcgcca gagctgctca cagtgttgat ccgtgaactg accgggaggg gaagatgatc
      481 tcactcccat caggtacccg tatctggctc gttgccggcg ttaccgatat gcgtaaatcc
      541 ttcaacggac tgggagaaca ggtacaacat gtgctgaatg ataatccctt ctccggtcac
      601 ctgtttatct tccgtggccg acggggtgac accgtcaaaa ttctttgggc tgatgctgat
      661 ggtctgtgcc tgttcaccaa acgcctggag gaaggccagt ttatctggcc tgcggtacgt
      721 gacggcaagg tatccattac ccgctcgcaa ctggcaatgc tcctcgataa gctggactgg
      781 cgtcagccaa aaacatccag ccgtaactca ctgacaatgt tgtaaaaaac tcctgaccgc
      841 attataaaaa cggtcatgag tcagaaatac ctcattcgca tcgcagagct ggaaaggttg
      901 ctctctgagc aggctgaagc cctccgtcag aaagaccagc aactgagtct ggttgaagag
      961 acggaagcct tcctgcgctc tgcactgaca cgtgccgaag aaaagatcga agaagatgaa
     1021 cgggaaatag aacatctgcg ggctcagata gaaaaactgc gccggatgct gttcggtacc
     1081 cgttctgaaa aactgcgtcg tgaagttgaa ctggctgagg ctctgctgaa acaacgtgaa
     1141 caggacagcg atcgttacag tgggcgggaa gacgatcctc aggttccccg ccagttgcga
     1201 cagtcgcgcc atcgtcgtcc gttaccggca caccttcccc gtgaaataca ccgcctggag
     1261 ccagaagaaa gctgttgccc ggagtgtggc ggtgagctgg attatctggg ggaagtcagc
     1321 gctgaacagc tggaactggt gagcagtgcc ctgaaagtga tccgcacaga acgggtaaaa
     1381 aaagcctgta caaaatgtga ctgtattgtt gaagcaccgg cgccgtcccg cccgatagag
     1441 cgtggtatcg cgggccccgg attacttgcc cgcgtgttaa cgggaaaata ctgcgaacat
     1501 ctgccactgt atcgtcagag tgaaatcttt gcccgccagg gtgtcgaact gagccgggcc
     1561 ttactctcca actgggttga cgcgtgctgc cagttaatga caccggtgaa tgatgccctg
     1621 taccgttatg taatgaacac ccgcaaggtt cacactgatg acacaccggt aaaggtactg
     1681 gcaccgggtc agaaaaaggc gaaaacaggg cgtatctgga cgtatgtccg ggatgatcgc
     1741 aatgtgggtt cgtcatctcc tccagcggtc tggttcgcgt actcgccgaa ccggcagggg
     1801 aaacacccgg agcaacacct ccgccccttc cggggtatcc tgcaggcgga tgcgttcaca
     1861 ggttacgaca ggttgttcag tgcagaacgt gaaggtggtg cactgacaga agttgcgtgc
     1921 tgggcccatg cccggcgaaa aatccacgat gtatacatca gcagcaaaag tgcgacggca
     1981 gaagaagccc tgaagcgaat cagtgaactg tacgccatcg aggatgaaat acggggatta
     2041 ccggagtcag agcgtcttgc cgtcaggcag cagcgaagca aagtgttact gacgtcgctg
     2101 catgaatgga tggtggagaa gaatggtacg ctgtcgaaaa aatccagact gggcgaagcg
     2161 ttcagctatg tactgaatca gtgggatgcc ctctgttatt acagtgatga cggtctggcg
     2221 gaggcggata ataatgctgc ggaaagagcg cttcgtgcag tctgtctcgg aaagaaaaac
     2281 tttatgttct ttggcagcga tcacggcggc gagcgtggag cactgttgta cgggctgatc
     2341 ggcacctgcc gtctgaacgg tatcgatccg gaagcgtatc tgcgccatat cctgagcgta
     2401 ctgccggaat ggccttccaa ccgagttgac gaactcctgc catggaacgt agtactcacc
     2461 aataaataag
//
LOCUS       DAPOXO010000213         2466 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.215, whole genome shotgun sequence.
ACCESSION   DAPOXO010000213 DAPOXO010000000
VERSION     DAPOXO010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2466
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.215"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            788..1291
                     /locus_tag="ROH59_005100"
     CDS             788..1291
                     /locus_tag="ROH59_005100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HDX4807456.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     AQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(1369..1620)
                     /locus_tag="ROH59_005101"
     CDS             complement(1369..1620)
                     /locus_tag="ROH59_005101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 domain-containing protein"
                     /protein_id="HDX4807457.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(1735..1821)
                     /gene="azuC"
                     /locus_tag="ROH59_005102"
     CDS             complement(1735..1821)
                     /gene="azuC"
                     /locus_tag="ROH59_005102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HDX4807458.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            2085..2408
                     /locus_tag="ROH59_005103"
     CDS             2085..2408
                     /locus_tag="ROH59_005103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecR-like lipofamily protein"
                     /protein_id="HDX4807459.1"
                     /translation="MRLLILTLSLITLTGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HARTDRYVSRGIADRACQQAGYTHAIPFGQPVGNCSLFAGSLCLNTEFTLSYQCHHSA
                     FPVFL"
BASE COUNT          698 a          539 c          517 g          712 t
ORIGIN      
        1 tccagcttta gtgtcgtttt gtgtagggca aaaacgaatg acattcgtta aattaatcgg
       61 aaaacaaagc attacctttt aactaaaaga taagtgactg tgttgacata gttttagcga
      121 gaaattaatt ctccatagga gagcaatatc acatcgcaga attacagtga gaacgtgcat
      181 aaatttagcg ggaaaagaca taaggaaaag cgaatttgtc agacaaatta tcgagtgcac
      241 agcagaataa tccataagat tagcctggaa gtccttgttg tctttggtac ccatgcggga
      301 tgtcttcttt ttaaccagtc aataggcctc attacctggc gttgagtttt tgcaatggtg
      361 taataaccgc aacttaaaga tgtggaaaat gcgcgtcatt catttcgcca ttaattatca
      421 ctgtgctcat taattaacag aacacgtata atgagagcca tatcgcaaaa atgaaaaaac
      481 gttttataaa atcattgcct catcatgaat tcaaattcat cgattaatat caataagata
      541 caaaaggcac catcattaaa attcattaca gttacattga tttcatcaat gaaatgtaaa
      601 aatataaact tgatgattta agcattttct tatacccgtt cagacgttat tcttatttca
      661 gatcatcgtc agaattgact ccacgatcac atttcggacc ggcagaaagg aattattctg
      721 caaacagtaa ttatggtgtt ttgatttatc ttgcacctct ccacttctgg atataaggat
      781 attaggtatg gcaaccgctg gaatgcttct caaactcaac tctcaaatga accgcgagtt
      841 ttacgcatcc aatctctacc ttcacctgag taactggtgt tctgaacaga gtctgaacgg
      901 caccgccact ttccttcgcg cccaggcaca gagtaatgtg acccaaatga tgcgcatgtt
      961 taactttatg aagagtgtcg gcgctacccc catcgttaaa gccattgatg ttcccggtga
     1021 aaaactgaac tctctggaag aactgttcca aaaaacgatg gaagaatacg agcaacgttc
     1081 aagcacgctg gcacagttag ccgatgaagc gaaagaactg aatgatgatt caaccgtcaa
     1141 tttcctgcgc gatctggaaa aagaacagca gcatgatggc ctgttactgc aaaccattct
     1201 tgatgaagtg cgcagtgcga aacttgctgg tatgtgtcct gtgcagaccg accaacatgt
     1261 tctgaatgtc gtgtcgcatc agctacattg atcatcatcg gcgctaatgc attgcgccga
     1321 tgaagttttt gagaaaccgc tgcctcattt ttttgaagca gcggtttttt aatgggattc
     1381 gccctgtggg gtaaacttga gttcaatcaa cgcgatggct ttttggattg cccgcatggt
     1441 gaccgggtct gcggcggcgg gatggttagt aaagtcgata ttcttcagct ggctggacat
     1501 tttttcgcga acttcaacgg gcgcgatcac atcgagaaca tccagaattt gtttgataac
     1561 caactggcaa gcaaccacat cagaaaccag ttcctgatcg gcattcagcg gctgggacat
     1621 cgtaaactcc tgatagcatt ttgaaagccg ttatagtagc ggcttcacat cttcagcgat
     1681 agtcacatcc accgtcatca gaacacaaaa aaacctgccg gagcaggttt tttgttatcg
     1741 gaacatattg cctggcggta cgtctttgaa cgtcttgcaa tagttattga acatactttt
     1801 caggatcttg cgcagtttca tcgcggtact ccgaccattt gttatacagg tgttattgtc
     1861 tttgcgttta taatatgaca accatcacaa aaatcaatct ttatgtgatg taaatcacat
     1921 aaatacccct ttaatgttat aaaaatgata atcaaaaaag cagccctcca atttctgaca
     1981 catacagatg gcaagaaata gcgcctgcca ggcgtctttt ccggccattg tcgcagcgct
     2041 gtaacgcgta aaatactgct ttcttttact cttctggctg gaccatgaga cttctgattc
     2101 tgactctttc cttaataacg ctgacggggt gtacggttac tcgccaggcc catgtgagcg
     2161 aagttgacgc ggcaacaggt attgttcggt tggtttatga tcaggctttt ttgcagcatg
     2221 cccgtaccga tcgttatgtc agtcgcggga tcgccgatcg cgcatgccag caggcaggct
     2281 atacccacgc tatccccttt ggtcagccag taggcaactg tagcctcttt gcgggttcct
     2341 tatgtttgaa tacggaattc actttgtcat atcagtgcca tcattccgcc ttccctgtct
     2401 ttctctaaac gttttaatca gcgaggggga tcttcgctga ttaaataaat agcggtaatg
     2461 cgtttt
//
LOCUS       DAPOXO010000214         2464 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.216, whole genome shotgun sequence.
ACCESSION   DAPOXO010000214 DAPOXO010000000
VERSION     DAPOXO010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2464
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.216"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            158..1660
                     /locus_tag="ROH59_005104"
     CDS             158..1660
                     /locus_tag="ROH59_005104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDX4807460.1"
                     /translation="MSVTNFLHGIRTLEYDDGTKEINTVDISVIGIVGTAPDSSYPTC
                     ASLLWGSELADNLVEFSTVMPGADGNNWIVEIVDLGINGNVATPGYSTLPDGSRKLTM
                     ITDGAMTPSKMYDQNQQYKEGLQIGEYINVTFGGDHAGTGTVFALPPTNLSGGKDESF
                     KYNVPTLIAGSQKKAGLLGGSGTLPPAVSEILNQEDAIIVVVRVEEDSDETKMRQNVV
                     NGINALLTSAQINQVTPRILIAPDYSANDYIAEQLEVVTNKLRGVGYIDSPRGATPAD
                     VVNRRQRYGGRMEILRPRVYSTSDVSGLSRPYSAIAAGLRARIDNEKGFWWSKSNQNI
                     YGITGLEQVDDFIIGETNCTANLLNASQVSTIIRYDGFRHWGNYLCSLSPQWSFECVR
                     RTADVIEDSIARAMMTDFIDRPIDLHLGTDVVESINAYLHKLEEQGAINGGRAWLDEE
                     LNTKESLAAGNLYINVDFGPKSPAQTITLMYRINNDYTVEALASLFKETV"
     gene            1678..2190
                     /locus_tag="ROH59_005105"
     CDS             1678..2190
                     /locus_tag="ROH59_005105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HDX4807461.1"
                     /translation="MADSNTYRAFALFVQGERVLNCTEYTPVDMKIIEDDFKTGAMDT
                     AITLDGGMEKMSASFKVSGSDSGVMGYLGLIPGAKTRFEIRSAYTDNYGVNFERIDTY
                     EGLITAITDDAQGTDSKSAVGQSVTIAPSYYKRVQNGKIIYEIHPAKMKRVINGVDVL
                     AGVARILHVY"
     gene            2203..>2464
                     /locus_tag="ROH59_005106"
     CDS             2203..>2464
                     /locus_tag="ROH59_005106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HDX4807462.1"
                     /translation="MESLLDSMTITLSRPFIIKGESRDTITIREPKLRDRIMFSNDKS
                     GLEERTATMLARLANLEREDLYALPACDYDQMEAAFNELVKPP"
BASE COUNT          741 a          487 c          605 g          631 t
ORIGIN      
        1 agactacatt acggactgtt ggcgatctgt caattgaggc attctcaatt cagtgtgcag
       61 tagatgccgg aaccgcatct gacgcgcaaa tcgaaaattt ggccgagctt aaagaagcaa
      121 tagcgacgcg aattggtgaa aatagagaag gaataaaatg agcgtaacta attttttaca
      181 cggtattcgc acgctcgaat acgacgacgg cacaaaagag atcaacacag tagatatttc
      241 cgtgattggg attgttggta ctgctcccga ttccagctac ccaacttgtg catcactatt
      301 atggggatca gagctcgcag acaatcttgt tgagttttcg actgtcatgc caggggccga
      361 cggaaacaac tggattgttg aaattgttga tttgggaatt aacgggaatg tagcaactcc
      421 aggatacagc acactgcccg acggttcgag aaaattaaca atgatcacgg acggtgccat
      481 gaccccgtca aaaatgtacg atcagaacca gcagtataaa gaaggactcc agattggaga
      541 atatattaac gtcacattcg gtggtgatca cgcaggaacg gggactgtat tcgcgctccc
      601 cccaacaaat ttatccggtg gtaaagacga atcgttcaaa tataatgttc cgacgttaat
      661 tgcaggcagt caaaaaaaag ctggattgct cggtgggtct ggaacccttc ctcccgctgt
      721 atctgaaata ctaaatcagg aggatgccat tattgttgtt gtccgcgtcg aagaggacag
      781 cgacgaaaca aaaatgcggc agaacgtcgt taacgggatt aacgcattgt tgacgtctgc
      841 gcaaataaat caagtaacgc cgagaatttt aatcgctcca gattatagtg ctaacgatta
      901 tattgcagaa caacttgaag tggtgacaaa taaattacga ggcgttggat atatcgattc
      961 accgcgaggc gctacgcctg ctgacgttgt aaatcgtcgt cagaggtacg gcggcagaat
     1021 ggaaattctg cgccctcgtg tttattctac gagtgatgtt agtggtttat ctcgtccgta
     1081 ttcagctatc gctgctggtt tacgagccag aattgataac gaaaaagggt tttggtggag
     1141 caaatcgaat caaaatatct acggaattac aggactcgaa caagtcgatg attttataat
     1201 cggtgaaacg aactgcacag caaatctgct gaacgccagc caggtcagca caattattcg
     1261 ctatgatgga ttcagacact ggggtaacta tctgtgtagc ctcagtcccc aatggtcctt
     1321 tgaatgcgtt cgtcggacag ctgacgtaat tgaggattca atagcccggg caatgatgac
     1381 cgattttatt gatcgcccga tagacctgca cctcggaaca gacgttgtag agtcgataaa
     1441 cgcgtatctg cataaattag aggagcaggg cgcgattaac ggaggacggg cgtggttaga
     1501 tgaagagtta aatacaaaag aaagtctggc cgctggtaat ctttatatta atgttgactt
     1561 tggaccgaaa tccccggcac aaacaattac gttaatgtac cgcattaata atgattacac
     1621 agttgaagct ctggcctctc tttttaaaga aacagtctaa taatctggag aattgatatg
     1681 gcagatagta acacctatcg tgcatttgcg ttgttcgtcc agggagaacg agttttaaat
     1741 tgcactgaat acactcccgt cgatatgaaa ataatcgaag atgattttaa gacgggcgct
     1801 atggatacag ctatcactct ggacggggga atggagaaaa tgtcagccag ttttaaagtc
     1861 tctggctccg attctggtgt gatggggtat ttgggattaa taccaggtgc taaaacaagg
     1921 ttcgaaattc gaagtgcata tactgacaat tacggtgtca attttgaacg tattgataca
     1981 tatgaggggc ttattacggc gattactgat gacgcgcagg ggactgattc aaaatcagca
     2041 gttgggcaat cagtaacgat tgcgccgagc tattataaac gagttcaaaa tggaaaaatt
     2101 atttacgaga ttcatcctgc aaaaatgaaa cgagtaatta atggtgttga cgttcttgcg
     2161 ggcgttgctc gtattctcca tgtatattaa aaggcaaata aaatggaatc attattagac
     2221 agtatgacta ttacgctctc tcgcccgttt attattaagg gggagagccg cgatacaatt
     2281 actattcgcg aaccaaaatt acgcgaccgc attatgttca gtaacgataa aagtggtctt
     2341 gaagagcgga cagcgacaat gctggcgcgc ctggcaaatc tggagcgtga ggatttatat
     2401 gcactgcctg cgtgcgatta cgatcaaatg gaggccgcat ttaacgaact ggtaaagcct
     2461 ccga
//
LOCUS       DAPOXO010000215         2443 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.217, whole genome shotgun sequence.
ACCESSION   DAPOXO010000215 DAPOXO010000000
VERSION     DAPOXO010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2443
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.217"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..354
                     /locus_tag="ROH59_005107"
     CDS             <1..354
                     /locus_tag="ROH59_005107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HDX4807463.1"
                     /translation="AITKDASTLNPEGYSVVEIPDITANRRADDSGKWMFKDGAVIKR
                     VYTEEELRLQTENQKKILLQQAREKTQFWQTQLTLGIITDSDRQQLMNWMRYVQQVET
                     TDTSVLPVTFPEPPE"
     gene            complement(385..912)
                     /locus_tag="ROH59_005108"
     CDS             complement(385..912)
                     /locus_tag="ROH59_005108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX4807464.1"
                     /translation="MQHLKNITAGNPKTIEQYQLTKKAGVIWLYTEDGKNWYDELKNF
                     QDDTLKIAYDQKGIIRCIEKDVSTLNPDGLSVVELPNITANRRADISGNWKFLDGKVV
                     KREYTKQELQQQAELQKAALLSEAESVIQPLERAVRLNMATDEERTRLESWERYSVMV
                     SRVDTAKPEWPQKPE"
     gene            complement(928..1896)
                     /locus_tag="ROH59_005109"
     CDS             complement(928..1896)
                     /locus_tag="ROH59_005109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4807465.1"
                     /translation="MTGELKIGTVNALRIFNDAFGLIFRRSEDFLHFIPTAEGQGENG
                     DIGPLRPFAINLRTGAISVSHGAKIDGGLALGTDNALGGNSITLGDNDTGIKQGGDGV
                     LLFYSNGQLAFGLQPASADFYKRVAYIHQGIIPDGSGAFADQLNNATAPFVQTQFAWN
                     PTPGGLYVPIVKGLSIRNGQGYPGAVSFGYLLTEQYGFPVPCIHMRGDGGNDALWQFN
                     PNDKSFISPGALIAGGVRYNTDGNIFGGCWGSNLNDYLNSSFIRNVRLGGRRSDTLYR
                     GGLCEPGNGHVTTGLQIIGEVDGDDWMVSRPLQKYISGNWYNVEQA"
     gene            2022..2204
                     /locus_tag="ROH59_005110"
     CDS             2022..2204
                     /locus_tag="ROH59_005110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDX4807466.1"
                     /translation="MLIGYVRVSTNDQNTDLQRNALVCAGYEQIFEDKLSGTRTGRPG
                     LKRALKRLQKGDALVV"
     gene            2250..2348
                     /locus_tag="ROH59_005111"
                     /pseudo
     CDS             2250..2348
                     /locus_tag="ROH59_005111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885581.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
BASE COUNT          666 a          581 c          532 g          664 t
ORIGIN      
        1 gccataacca aagatgcctc cacacttaac cctgaaggtt atagcgtcgt tgagattcct
       61 gatattaccg ccaaccggcg tgctgacgac tcaggtaaat ggatgtttaa agatggcgca
      121 gtcattaaac gtgtatatac cgaagaagag ttgcgcctac agacggaaaa ccagaaaaaa
      181 atattattac agcaggccag agaaaaaacg cagttctggc aaacacagct tactttgggg
      241 attatcactg attcagacag acagcaactg atgaactgga tgcgatacgt gcaacaggtt
      301 gagacaactg atacctcggt tcttcctgta acattcccgg aaccaccaga ataagaaaag
      361 gcccgtacgg gccttaattt gttgttattc tggtttctgt ggccattcag gctttgcagt
      421 atccacacgg ctgaccataa cgctgtagcg ttcccatgat tccagtcgtg tgcgttcctc
      481 atcagttgcc atattcagtc tgacagcacg ttccagcggt tgaatcacag actccgcttc
      541 ggaaagcaaa gcggcttttt gtaactctgc ctgctgttgc agttcctgtt ttgtatattc
      601 ccgctttact actttaccat ccagaaactt ccagtttccc gagatatcgg cgcgacggtt
      661 ggctgttata ttcggtaact caacaacact taacccgtca gggttaagtg ttgatacgtc
      721 tttctcaata caacgaataa tccccttctg gtcataagct atttttaaag tatcatcctg
      781 aaagtttttt aattcgtcat accagttttt accgtcttct gtatatagcc agataacgcc
      841 agcttttttc gtaagctgat actgctcaat ggttttgggg tttccggcgg taatattttt
      901 cagatgttgc atatattctc ctgatggcta tgcctgttca acgttatacc agttaccaga
      961 aatgtatttt tgtagtggtc gtgacaccat ccagtcatct ccatcaacct caccaataat
     1021 ttgcaatcct gttgtcacat gaccattacc tggttcgcaa agtcctccgc gatataatgt
     1081 gtcagaacgt ctgcctccca gacgcacatt tctgataaaa gaactattca ggtaatcatt
     1141 taagtttgac ccccagcacc caccaaatat atttccatcg gtgttataac ggacgccacc
     1201 cgcaataaga gcacccggtg aaataaagga tttatcgttc gggttaaact gccataaagc
     1261 atcattaccg ccatcgccac gcatatgaat acatggaacc ggaaatccat actgttctgt
     1321 cagtaaatac ccaaagctga ccgcgccggg atagccctgt ccattgcgaa tggacaagcc
     1381 cttaactatc ggcacgtaaa gaccaccagg agtgggattc caggcaaact gcgtctgaac
     1441 aaaaggcgcg gtggcattat tcaactggtc tgcaaatgcg ccacttccat caggaattat
     1501 tccctgatga atatatgcaa cccgcttata aaaatcagca gatgcgggtt gaagcccaaa
     1561 tgccagttgt ccatttgaat agaataaaag gacaccgtcg ccgccctgtt taataccagt
     1621 gtcgttatct ccgagagtaa tggaattacc gcccagtgcg ttatctgtac caagcgccag
     1681 cccaccatca attttggccc cgtggctgac agatatagca cctgttctca gatttatagc
     1741 gaatggcctt aatgggccga tatcaccgtt ttcgccttgt ccttcagccg tcggaatgaa
     1801 atgaagaaaa tcttctgaac gacggaaaat aagaccgaag gcatcattga aaattcgcag
     1861 cgcattcacc gtgccaattt tcagttctcc ggtcatttta tcgccggaac gctgaacggc
     1921 gttaccagcc ttgtttaccg tttcctgtaa accgaggttt tagataatgg cggtttctgg
     1981 cctgcatggc atgatttgtg cttttggacg ggagattcag cgtgctgatt ggctatgtaa
     2041 gggtatcaac aaatgaccag aatacagatc tgcaacgaaa cgctcttgtt tgtgcaggat
     2101 atgaacaaat atttgaagat aaattaagcg gaacaaggac aggccgacct ggattaaaac
     2161 gtgctttaaa gcgccttcaa aaaggtgacg cactggttgt ctgaaaactg gactgactgg
     2221 ttcactgtat gcggcatctt gtcgtgctgg tggtggaagc ctagaaaaag tatcgggtgt
     2281 tactgaaccg tgttgataca tcaactgcac ctgatattga gtggcctacg aaccctgtca
     2341 gggagtaatc attgggatta tgccgcagca cgtcttaagc aagaacgtgc tgcggttgga
     2401 tgctattttt tccctgaagc ggaaaacatt actacagtac ctt
//
LOCUS       DAPOXO010000216         2411 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.218, whole genome shotgun sequence.
ACCESSION   DAPOXO010000216 DAPOXO010000000
VERSION     DAPOXO010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2411
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.218"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..136
                     /locus_tag="ROH59_005112"
     CDS             <1..136
                     /locus_tag="ROH59_005112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDX4807467.1"
                     /translation="IGHDDWDKLEYFINSSVKPMDYDSLYKFSPDKMMSTIVYDFIEK
                     "
     gene            180..1259
                     /gene="waaB"
                     /locus_tag="ROH59_005113"
                     /gene_synonym="rfaB"
     CDS             180..1259
                     /gene="waaB"
                     /locus_tag="ROH59_005113"
                     /gene_synonym="rfaB"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,6-galactosyltransferase"
                     /protein_id="HDX4807468.1"
                     /translation="MKIAFIGEAVSGFGGMETVIRDVITTFRQQHIYSEMFFFCRNDK
                     MDKGWLEGIKYSCSFSNIRLGFLRRAKHIHALSKWLQDYQPDVVICIDVISCLYAAKA
                     RKKSGIDVPVFSWPHFSLDHKKHAEYITCADYHLAISSGIKQQMINRGVPESTINVIF
                     NPVEAKDTVIPGPEEGETATFIYVGRMKFEGQKRVKDLLDGLSQAQGDWKLHVLGDGS
                     DFEKCQAYGRELKIDNRIVWHGWQKHPWEVVRQDIKKVSALLLTSSFEGFPMTLLESM
                     SWGIPCISADCVSGPGDIIQPDVNGHLYQPGDIAGFVTLLNKYIAGEIHIEHEKIPAS
                     IDKFYQSKYYDRLHNIIISAISRRK"
     gene            1259..2278
                     /gene="waaO"
                     /locus_tag="ROH59_005114"
                     /gene_synonym="rfaI"
     CDS             1259..2278
                     /gene="waaO"
                     /locus_tag="ROH59_005114"
                     /gene_synonym="rfaI"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     3-alpha-galactosyltransferase"
                     /protein_id="HDX4807469.1"
                     /translation="MQQVFFQETEYLNSVIDYNHKVETENLCLDIAYGTDKNFLFGCG
                     ISIASILKYNEGSRLCFHIFTDYFGDNDRKYFDALALQYKTRIKIYLINGDRLRSLPS
                     TKNWTHAIYFRFVIADYFISKVAKVLYLDADIICQGTIEPLIKFSFPDDKVAMVVTEG
                     QADWWEKRAHSLGVAGISKGYFNSGFLLINTAKWAAQQVSARAIAMLNEPEVIKKITH
                     PDQDVLNMLLADKLIFADIKYNTQFSLNYQLKESFINPVTNNTIFIHYIGPTKPWHDW
                     AWDYPVSQAFMEAKNASPWKNTALLKPNNSNQLRYSAKHMLKKHRYLKGFSNYLFYFI
                     EKIKH"
BASE COUNT          764 a          381 c          492 g          774 t
ORIGIN      
        1 aataggtcat gatgattggg ataagttaga gtattttatt aattcatctg ttaaaccaat
       61 ggattatgat agtttatata aattcagccc tgataaaatg atgtcaacaa ttgtttatga
      121 ttttatagaa aaataaaacc gttaaaacag tgagttttac tcaattaatg agagtttcaa
      181 tgaaaatagc atttatcggc gaagctgttt ctggatttgg cggcatggaa acggtcattc
      241 gtgatgttat tactaccttc aggcaacaac atatctatag tgaaatgttt ttcttttgtc
      301 gtaatgataa aatggataag ggatggctgg aaggtattaa gtactcgtgt tcattttcca
      361 atattcgctt aggttttttg cgtcgggcga aacatattca tgctttaagc aaatggcttc
      421 aagattatca gccagatgtt gttatttgta ttgacgttat ctcgtgtttg tatgcggcca
      481 aagcacgtaa aaaatcagga attgatgtgc cagtattttc atggccgcat ttttctttag
      541 atcacaaaaa acatgctgaa tatatcacct gtgcagacta tcatttagcc atcagctctg
      601 gcattaaaca gcaaatgatt aatcggggtg taccagaatc gacgataaat gttattttta
      661 atccagtcga agctaaagac acagtcattc ctgggcctga ggaaggtgaa acggcaacgt
      721 tcatttatgt tgggcgtatg aaattcgagg gccagaagag ggttaaagac ctgcttgatg
      781 gtttatcaca agcgcaaggt gactggaaac tccatgtact gggtgatggt tctgattttg
      841 aaaaatgcca ggcatatggt agagaattga agattgataa tcgaattgtc tggcatggtt
      901 ggcaaaaaca tccatgggag gtagtgcgtc aggatattaa gaaagtcagt gcattgttat
      961 taacctcatc ttttgaaggt tttccaatga ccttacttga atcgatgtca tgggggattc
     1021 cgtgtatcag tgccgattgt gtctccggtc ctggtgacat tattcaacct gatgtcaatg
     1081 gccatttgta tcaaccggga gatattgctg gttttgttac tcttctaaat aaatatatag
     1141 caggtgaaat tcatatcgaa catgaaaaaa ttcctgcgtc gatcgataag ttttatcaat
     1201 ctaagtatta tgatagatta cataatataa ttatttctgc tatttcccgg aggaaataat
     1261 gcagcaggta tttttccagg aaactgagta tctaaattca gttattgatt ataatcataa
     1321 agtagaaaca gaaaatcttt gtctggacat cgcttatgga actgacaaaa actttctatt
     1381 tggttgcgga atttcgattg cttcaatatt aaagtataat gaaggaagtc ggttgtgttt
     1441 tcacattttt actgattatt ttggtgataa tgatcgtaag tattttgatg ccctggcgtt
     1501 acagtataaa accagaatta aaatatatct gattaatggt gatcgactgc gctcattgcc
     1561 tagcacaaag aactggactc atgcaatata ttttcgtttt gttattgctg attactttat
     1621 tagtaaggtg gctaaagtcc tttatctgga tgcagatatc atttgtcagg ggactattga
     1681 gccactaatt aaattctcat ttcctgacga taaagtcgca atggttgtta cagaagggca
     1741 agctgactgg tgggaaaaac gcgcccattc gttaggtgtt gcgggaattt ctaaaggtta
     1801 ctttaactcc ggttttttat tgattaatac tgccaaatgg gcagctcagc aggtttctgc
     1861 acgagccatt gcaatgctaa atgagccaga agtaatcaaa aaaataacac atcctgatca
     1921 ggatgtatta aatatgttgc tggcagataa acttattttc gctgatatta aatataacac
     1981 ccagtttagc ttaaattatc aactaaaaga aagctttata aacccagtaa ccaacaatac
     2041 tatttttatc cattatatcg ggccaaccaa gccctggcat gattgggcct gggattatcc
     2101 tgtatcacaa gcctttatgg aggcaaaaaa tgcttcgcca tggaagaata cagcgttgct
     2161 gaaaccgaac aatagcaatc aattaagata tagcgcaaaa catatgctta aaaaacatag
     2221 atatctaaaa ggatttagca actatctttt ttattttatt gaaaagataa agcattaaaa
     2281 ctgggaaaca ataaagtaat gatataaggg tagcattgtg gactcatttc ctgccataga
     2341 gatagataaa gttaaagcct gggattttcg gctggctaat ataaatactt ctgaatgttt
     2401 aaatgttgcc t
//
LOCUS       DAPOXO010000217         2397 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.219, whole genome shotgun sequence.
ACCESSION   DAPOXO010000217 DAPOXO010000000
VERSION     DAPOXO010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.219"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1638
                     /gene="acrF"
                     /locus_tag="ROH59_005115"
     CDS             <1..1638
                     /gene="acrF"
                     /locus_tag="ROH59_005115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HDX4807470.1"
                     /translation="PALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI
                     LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLD
                     QVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHR
                     AKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQ
                     HPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG
                     RVKKVYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS
                     MEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFV
                     VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK
                     NAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSG
                     AQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCFKG"
     gene            1891..2112
                     /locus_tag="ROH59_005116"
     CDS             1891..2112
                     /locus_tag="ROH59_005116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807471.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
BASE COUNT          586 a          546 c          593 g          672 t
ORIGIN      
        1 cccgcgttat gtgcaacatt gctgaaacca gtctctgccg agcatcacga aaataaggga
       61 ggattcttcg gctggtttaa caccactttc gatcatagcg ttaatcacta caccaatagc
      121 gttggcaaaa tcctcggttc cacagggcga tatttactga tctatgcgct gattgttgca
      181 ggaatggtgg tgttgttttt acgtcttccg tcttccttct tacctgaaga ggatcagggt
      241 gtctttctga ccatgattca gttacccgct ggcgcgacgc aagagcggac gcaaaaagtg
      301 ttggatcaag tgacggatta ctatctgaag aacgagaaag cgaacgttga aagtgtcttt
      361 acagttaacg gctttagctt cagcggccag gcacaaaacg ccggtatggc cttcgtcagt
      421 ctgaaaccgt gggaagagcg tagtggtgac gaaaacagtg cggaagcagt aatccatcgt
      481 gccaaaatgg aattgggcaa gatccgcgac ggttttgtca ttccatttaa tatgccagcc
      541 attgttgaac taggcacggc aacgggtttc gactttgagt taattgatca ggctgggctg
      601 ggtcacgatg ccctgaccca ggcccgtaac cagttgcttg gcatggcggc gcaacatcct
      661 gccagcttag tcagcgtgcg ccctaatggc ctggaagaca ccgcgcagtt taaactggaa
      721 gttgaccagg aaaaggcgca ggcattaggt gtttcacttt ctgacatcaa tcagaccatt
      781 tcaacggcgt tgggtgggac ttacgttaac gacttcatcg accgtggtcg cgtgaaaaag
      841 gtgtatgttc aggcggatgc caaattccgt atgctgccag aagatgtcga taaactttat
      901 gtccgcagcg ccaacggcga aatggtgcca ttctctgcct ttaccacttc acattgggtg
      961 tatggctctc cgcgactgga acgctacaac ggtctgccgt caatggagat tcagggggaa
     1021 gccgcgccag gaaccagttc cggcgatgct atggcgttga tggaaaacct tgcgtcaaaa
     1081 ttaccggcgg gcattggtta tgactggacg ggtatgtcat atcaggaacg tttatcggga
     1141 aaccaggctc ccgctctggt agcaatttcc tttgtggttg ttttcctgtg ccttgctgca
     1201 ctctatgaaa gctggtcaat tcctgtctcg gttatgttgg tcgtgccgtt agggattgtc
     1261 ggcgtgctac tggcggcaac actctttaat caaaaaaatg acgtctactt tatggtgggc
     1321 ttgctaacga caattggctt gtcggccaaa aacgctattt tgattgttga gttcgctaaa
     1381 gatctcatgg agaaagaggg taaaggtgtt gttgaagcga cactaatggc agtacgtatg
     1441 cgcctgcgtc ctatcctgat gacctctctc gcctttattc tcggcgtatt accgctagct
     1501 atcagtaacg gtgccggcag tggcgcgcag aacgcagtgg gtatcggggt aatgggcggg
     1561 atggtttctg caacgttgct ggcaatcttc ttcgtgccgg tgttctttgt ggtgatccgc
     1621 cgttgcttta aaggataaat cagaaacata aaggcacttt cgggtgcctt tattatttcc
     1681 agtgaaaccc ataaaaatta ataagatatt cctctactca ctttttaaaa actttctata
     1741 gttcccgctc ccttcactat ttttacaatt cacataattt gtcattattc attccgcaag
     1801 atttataacc tccagtgata aaatggcatt cagctcgtta ataagagagt taacttatta
     1861 agcgttagcg tttattactg aggtaacacc atgaaaagat taattcctgt ggcattgctc
     1921 accgcattgc tggcgggctg tgctcacgat tcgccctgcg ttccggttta tgacgatcag
     1981 ggtcgactgg ttcacactaa tacctgtatg aaaggcacga ctcaggataa ctgggaaacg
     2041 gctggggcta ttgccggcgg ggcagcagct gttgctggcc tgacgatggg gatcatcgct
     2101 ctgtcgaaat aactaaacag ggcgcggagc tccgcgctct ttttaacgat acagtatctt
     2161 tccataagat aaaatattgc tatattctgc tgggtaattc cctgctgatt tagcatgtta
     2221 tatcacgtta tttcgctgct ttcgaaataa cgcatcaatt taactttcac acttcccacc
     2281 agaaatatac tcacgctaac aatcattatt ctgcttagta aaaaacgcgt aaatattttg
     2341 cgccaaaatg tggcgcatgt ttcattttcg caccattacg aggcgctgtt tttatta
//
LOCUS       DAPOXO010000218         2321 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.220, whole genome shotgun sequence.
ACCESSION   DAPOXO010000218 DAPOXO010000000
VERSION     DAPOXO010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2321
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.220"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            89..343
                     /locus_tag="ROH59_005117"
     CDS             89..343
                     /locus_tag="ROH59_005117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000788354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX4807472.1"
                     /translation="MKNGIDVSVIIPAYNAAETSVSLVTKILSEPHLAIELIIVDDGS
                     TDETGNVLRQIHDDRLILIEQANQGVYAARNAALALHQGE"
     gene            1447..>2321
                     /locus_tag="ROH59_005118"
     CDS             1447..>2321
                     /locus_tag="ROH59_005118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HDX4807473.1"
                     /translation="MDLVDSVEAGKLTISELIDALAKDKNYSASKWDQRYREFTTLLQ
                     QTSTFSEPETDGLVKRLWYERDNGIASIRQGVPSLAEYQQSLPLLRELTERIRQQPDE
                     ETYQYVGNALQQAKENGLLKRMYRSLRNRVFAAFSPENYTSTVDENAFSKAAEFLNQH
                     FHLGLALTGNWLQKNYELKQAIHAQSPDTDPYYVNMAIWHLYELLRERDNEQKQEKIA
                     STTFITSNEPIENKIILHSPTNVIFFGPPGTGKTFRLQQKMKEYTSHAVPADRDAWLD
                     SRLESLNWMQVITLVL"
BASE COUNT          710 a          523 c          495 g          593 t
ORIGIN      
        1 attcgatatc gatgaggaaa tcagggaaag aaggattatc acgatcagac gcctcaaaga
       61 tgacaacgaa agaaaatcgt agctcaatat gaaaaatgga atcgatgtca gcgtcattat
      121 ccctgcttac aacgccgctg aaaccagcgt tagtttggtt actaaaatcc tcagtgaacc
      181 ccacttggct attgaactta tcattgtcga tgacggttct actgatgaaa ctggcaacgt
      241 tcttcgtcaa atccacgatg atcggctcat tctcattgag caggccaatc aaggtgtcta
      301 tgccgcccga aatgctgctc tagccttgca ccaaggagaa taggttatat tccttgatgc
      361 ggacgacgat atagcagatg ggttcataga aaaaagatgg caggcagtta gtacgtcgca
      421 agccgacgtc atgatcttta atggctggca ttcctgtgct gaccaacatc gaagagcggt
      481 tcacaaaaag cagccctatg gtacgcctct gtcaggttat taatggatta gacactgtgt
      541 tacacaccgc gaatggccgc attatctgtg gctgcagatg gtcaggccat cctatgtcag
      601 gcagcattca ctgcgcttcc agtccggcag gagccataaa gacatttttt aaacggttca
      661 tcttgcagcg agcaatggtt gattctgtac attggatata aaggactata tctatatcaa
      721 caataaggcc tctatcacac atcggccgga ttactacgtt gttcgtgcta taaactatgt
      781 tgaagtgatc gcgaaaatca tccaagtagc ggaacaagaa caaaacaaaa aataaaggta
      841 tttttgtacc ggcatgcgct ggtagaggca cgtcattttt tgggactcta ccgcaatcgc
      901 gttggggata aatcgggcat gaaggactgc ttcaaagcga acatattcgc agcccattta
      961 ttcagaggta tcagcagttt tagcgatgtg tttttcttta ttaagctgct gggcaagcta
     1021 ttctgataag ttgtgcgttg ctacacgaca ccagcgcaca gcttaatttc acgctttctg
     1081 actaaattgt tcaggccttt tctataggtg caaacacaac tccccgtact ttcctcttcc
     1141 aactcaaaat catcgcacct tgctgaccca agaagggagc ataccctgca ctagtatccg
     1201 cacagctaat actctattga taccaacaac gcttcagcac aacaaagtaa ctcgataatc
     1261 acaactcaaa gtgaagatgc caaaaactcg tttgagagca ataaattcaa taacatgaaa
     1321 aaaatgtatt ttgcattgaa aatcttactt attgcgcttg gctacaattg catgcttggt
     1381 aatatagatt ataaaacacc agactagctg cctggtaagt aatgtaatag cagaggaaat
     1441 atcacgatgg atcttgtaga tagtgtcgaa gcaggtaagc tgacgatcag tgaattgatt
     1501 gatgccctgg cgaaagataa aaattactca gcttccaagt gggatcagcg ataccgtgaa
     1561 tttacgacct tgctacaaca aacctcaact ttttctgaac ctgaaacgga tggtttagtc
     1621 aagaggctct ggtatgaacg cgataacggt attgccagta ttcgccaggg cgttccatcc
     1681 ttagcagaat atcagcaaag cctgccactg cttagagaac taactgaacg aattcggcaa
     1741 cagccggatg aagaaactta ccaatatgtt ggcaatgcac tacaacaagc taaagaaaac
     1801 ggacttctca agcgtatgta taggagtttg agaaatcgcg tctttgccgc gttctcgcca
     1861 gaaaactaca ccagtactgt ggatgagaat gcttttagta aagcagcaga attcctaaat
     1921 cagcacttcc atctcggtct ggcactgacc ggaaattggt tacagaaaaa ctatgaattg
     1981 aaacaagcca tacacgccca atctcctgac acagatcctt attacgtgaa tatggccatc
     2041 tggcatctct atgaattgct ccgtgaacgc gataatgaac aaaagcagga gaaaatagcg
     2101 agcactacat tcataaccag caatgagccc atcgagaaca agatcatcct acattcacca
     2161 actaacgtga tcttctttgg cccccctggc actggcaaaa ccttcaggtt gcagcaaaaa
     2221 atgaaagagt acacttctca tgctgttcca gctgatcgtg atgcctggct ggattctcgc
     2281 cttgaatcgt tgaattggat gcaggttata acgctggtgc t
//
LOCUS       DAPOXO010000219         2321 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.221, whole genome shotgun sequence.
ACCESSION   DAPOXO010000219 DAPOXO010000000
VERSION     DAPOXO010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2321
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.221"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(33..983)
                     /gene="cbl"
                     /locus_tag="ROH59_005119"
     CDS             complement(33..983)
                     /gene="cbl"
                     /locus_tag="ROH59_005119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HDX4807474.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPLDHPLTQITPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLPA
                     DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEKNLIRLDTRHLFDANTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKRQVMENSEEEIDYQI"
     gene            complement(1085..2002)
                     /gene="nac"
                     /locus_tag="ROH59_005120"
     CDS             complement(1085..2002)
                     /gene="nac"
                     /locus_tag="ROH59_005120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="HDX4807475.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN
                     QQLLIRTKRGVTPTGAGKILYTHARAILRQCEQAQLAVHNVGQSLSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEVVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAVRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVISSPVMEKRQWQLVS"
BASE COUNT          620 a          596 c          507 g          598 t
ORIGIN      
        1 ctgaaaagcc cgcttttata gcgggctttt tgctatatct gataatcaat ttcctcttca
       61 ctgttttcca tcacctggcg cttgatatcc tcaactgaca gtcctgcatt acaaagttcc
      121 agaaagcgcc agacatagtt acgctgaagt tgccctcgct tcagtcccaa ccagacagta
      181 ttagcatcga aaagatgccg cgtatccagg cggattaaat tcttttcctc ttgttcgccg
      241 ctggattgtt cggcaactaa tccgatccca agcccaagag caacataggt tttaatgaca
      301 tcagaatcct gtgcacttaa tacaatatct gccggcaaac ctttgcgggc aaatgcgtca
      361 tcaatgcgtg agcgccccgt aatcccctgt cggtaagtaa ttaacggcca cttcgctatt
      421 gattccagcg tcaacggtgt aatttgcgtc aagggatgat cgagtggaac aagcaaacta
      481 tggtgccaac gaaaccacgg gaaggcgacg agctgcgggt cattactcaa acgctcgctg
      541 gcgataccaa tatcagcttc gccattttgc aacaacgtcg caatttcctg tggtgtaccc
      601 tggattagct ccagccgaac ctccgggaaa agttcgcgaa aagctttaat gacctcaggc
      661 aagctataac gtgcctgagt atgcgtcgtt gcaatagtga gaacgccaga cgtatcgttg
      721 gtaaacaggt ctgcgagccg acgaacatta ctggcttcat tcagaatgcg ttctgcaatg
      781 accagtaatg ctttgcccgg ttcagtcatg cccagcagtc gcttacctcg tcgaacaaat
      841 atttcgatgc caagttcatc ctccagttcc cgaatatgac ggctaacgcc tgactgtgag
      901 gtaaaaagca tattcgcaac ctctgtcagg ttgtaatcct gacgtgcagc ctcgcggatt
      961 atctttagtt gttggaaatt cacggtaaac tccgggcagt tcagatatcc cgttattgtt
     1021 aaagtctaat gcccggcata acaaataata aaaacccgca tcttattcca tcccgatata
     1081 acgcttagct caccaattgc cactgccttt tttccatcac tggagaacta atcactgaca
     1141 ttaacaactc tttcactgcc tgtgcctgtg gtgacaagtt tgctctggcg ggtaaattta
     1201 aggacaaaga gagactcatt gaaggagtgg taatgcgtga catccaccca tttactgcgc
     1261 cacataacga acgcgcagcc gattcaggta atactgcaac gcccatgccg ctggcaatcg
     1321 ctgcggtaag cgtggcaata gactcaattt caccaatgac ttttgccgtg agccgccgta
     1381 gggaaaaagc ctcatcaaca cgaagtctaa cagcgctgta atcactgggg agaaaaaggt
     1441 tcatttgcgc aatagcatta acatcaacgc tttgccccgg gcaatcttga gttcctacca
     1501 ggaaaagatc ttctttcagc aaagcctgac tggatacccc agccacaggg gaatgctcat
     1561 aaatcaccgc catatcgagt tggtgattta tcagtttttc gttaagcact gcaccactat
     1621 tttcatgaag atagataacg acctccggga attcagcgcg aaccgcctgt aataagggca
     1681 tggtgatgga tgacgcagcg gttcctggcg caaagccaat cgagacttgc cccgataatg
     1741 actgaccaac gttatgcacc gccagttggg cctgctcaca ctgacgtaaa atggcccgtg
     1801 catgggtata gagaattttt ccggcgcctg ttggcgtaac gccccgtttt gtgcgaatca
     1861 aaagctgttg atttaactca ccttccagtg tggcaacctg ctggctgagc gctggttgtg
     1921 cgatatgcaa tacttcagca gcctgggtca ggctaccaat atctacaatt tttacgaagt
     1981 atttcaggcg tctgaagttc atgttgcctc cggtttttaa gaatcggccc aagtgccgcc
     2041 attacttaca accagaatgc aagatgcttg ccagttctat tttagcgttg atgcgcaagc
     2101 taaccaactg tcaaataaga gattatgata gattcgtcat tggccctttt tatcagcagt
     2161 cgcattcacc tgccctataa aaggggggta tgcaccacga tggttcatta cccaataaga
     2221 ttgaaagctc accactttgt tgaaattgtc agcaaacaaa caaaaaaatg catttcaccc
     2281 tttgacatca ccatgcactg ccattaatat gcgccccgtt c
//
LOCUS       DAPOXO010000220         2311 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.222, whole genome shotgun sequence.
ACCESSION   DAPOXO010000220 DAPOXO010000000
VERSION     DAPOXO010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2311
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.222"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..391)
                     /locus_tag="ROH59_005121"
     CDS             complement(<1..391)
                     /locus_tag="ROH59_005121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2931 family protein"
                     /protein_id="HDX4807476.1"
                     /translation="MEFNIKLLFVITSMVLNFNAAAKEKISLLAPYDEWYFNFFYPNS
                     LPAEVTYVELLDTDGIYYQFRTLASTNASPGSVGQWSEKVSGMSSVFNKAKNPPMSIH
                     FCWDSVIDKKVYETWITLAGDVWKLMLT"
     gene            complement(381..>2311)
                     /gene="hcp"
                     /locus_tag="ROH59_005122"
     CDS             complement(381..>2311)
                     /gene="hcp"
                     /locus_tag="ROH59_005122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HDX4807477.1"
                     /translation="SVGNRYQQGHEDEIFVFSFQGGVSNTGFGINHQAIQFCKILDKS
                     SPLLMNCINNNERCRFEFYFYRINKYGKWERYYYIEVRGATLTQNQIIIKENELDYQY
                     ITIHYEYIYCKHLTANTEFSYLLTPENYNRLFPPTLLPVEEKPEIPPEREIILTIGVF
                     FDGTGNNLTNTNLRMSFCQPETYGLDVQDLASFNKQCMSKQGKTGSGVQSYLNYYTNI
                     HWLNKLYHRQLVLDDDVFNIQEKIYIEGIGTENNKADSLVGMGLGNNDTGVIAKTDRA
                     ISLLRETLAKIIVDLKDAKLVIKRLQFDVFGFSRGAAAARHFTNRVFERDPVLIKTIA
                     TAFQSVEYLGKPSGEVQFLGIFDTVAAIGGLMDGFDPHDGNNFPVKVKLPPGVAKHVF
                     QLTAMNECRYNFCLNSIKESWPELSFPGSHADIGGGYDPLEDEYLFLSRPAIETVLGN
                     VPVEATSAYQKAAQQAELLWRHSTLAPILPSGVLKIESNIDEIASPDHLGNVRKRVAA
                     AVTFRRTITNDWSKIALRVMYEVAKEAGVVFDAISVADKELKVPSHLKVICEKAISQG
                     KAVLLCTAPMPFSDDELKTIGKYLHCSSNWNTVDYRLKNKVSAEVSAFKTFSFVNRPD
                     ENWTRTIYDMQGNKQNGI"
BASE COUNT          666 a          510 c          412 g          723 t
ORIGIN      
        1 gtgtgagcat caatttccag acgtctcccg ccagtgttat ccaggtttca tacacttttt
       61 tatcaatcac tgaatcccag caaaaatgga tagacattgg tgggtttttg gctttattaa
      121 aaactgacga catccctgat actttctcgc tccattgtcc aacacttcct ggactggcat
      181 tagtactcgc cagagttctg aactgataat agatgccatc ggtatctaat aactccacat
      241 aggtaacttc tgctggtagg gaattagggt aaaaaaaatt gaaataccat tcatcatagg
      301 gtgcaagcag tgatattttt tctttcgctg ctgcgttaaa gttaagaacc atagacgtaa
      361 taacaaacag taattttata ttaaattcca ttttgtttat tcccttgcat atcgtatata
      421 gttctggtcc aattttcatc cggccgatta acaaaactaa acgtcttaaa cgctgatact
      481 tcagcagaca ccttattttt taatcgataa tcgacggtat tccagttgga agagcagtgt
      541 aaatatttcc caatggtttt aagctcatca tcagaaaaag gcatcggcgc tgtacacaag
      601 agaacggctt taccctgaga aattgctttt tcacatatta cctttaaatg actgggaact
      661 tttaattcct tatcagcaac agaaatggca tcaaatacta cccctgcctc tttagcgact
      721 tcatacatta ctcttaacgc aatctttgac cagtcattgg tgatcgttct gcgaaatgtc
      781 accgctgcag cgacccgttt tctcacatta cctaagtggt caggcgacgc tatttcatca
      841 atattggatt caatttttag gacaccagaa ggcagaatcg gagccagcgt tgaatggcgc
      901 cacaataact ctgcctgctg tgctgctttt tggtaagcgc ttgtcgcttc caccggcaca
      961 tttcccagta ccgtttcaat cgccgggcga cttaaaaaca ggtactcatc ttccagtggg
     1021 tcatagccgc caccaatatc agcatgtgat ccagggaaac ttaattctgg ccagctttcc
     1081 tttatgctgt tgaggcaaaa gttatagcga cattcgttca ttgctgtgag ctggaataca
     1141 tgtttggcca cacctggcgg taacttcact tttaccggaa agttattacc atcatgaggg
     1201 tcaaaaccat ccatcagccc tccgatggct gcaactgtgt caaaaatacc taaaaattgc
     1261 acttccccgg aaggtttacc taaatattca actgactgaa atgccgtcgc aatggtttta
     1321 atcagtacgg gatcacgttc aaatacgcga ttagtaaagt gccgtgcggc tgccgcccca
     1381 cgactaaagc caaatacgtc aaactgtaga cgcttaatta ctagtttagc atcctttaaa
     1441 tcaacaataa tctttgccag tgtctcacga agcagtgata tcgcacggtc agttttggca
     1501 attaccccag tatcattatt tcctagcccc attcctacca gagagtctgc tttattattt
     1561 tcagtgccaa taccttcaat atatattttt tcctgaatat taaatacatc atcatctaaa
     1621 actaattgcc gatgatacaa cttattcaac caatgaatat tcgtatagta attcaaatag
     1681 ctctgtactc cggatcccgt tttaccctgc ttgctcatac attgtttatt aaacgaggcc
     1741 aaatcctgga catccagacc ataggtttct ggttggcaaa aactcatacg taaattcgta
     1801 ttggttaaat tgtttcctgt gccatcaaag aatacgccaa tggtgaggat aatttctcgt
     1861 tcaggcggta tttctggttt ttcctcgaca ggtaagagcg tcggtgggaa aaggcgatta
     1921 taattttcag gtgtgagtaa ataactaaat tctgtattgg ctgtaagatg cttacagtag
     1981 atatattcgt agtgtattgt tatatactga tagtcgagtt cattttcttt tattataatc
     2041 tgattctgag ttaacgtggc accacggact tcaatataat aatacctttc ccattttcca
     2101 tatttattaa tacgataaaa ataaaactca aaacggcatc gttcgttatt attaatgcaa
     2161 ttcatcagca gcggtgagct tttatcgaga attttacaaa attgtatcgc ttgatgatta
     2221 atgccaaatc ctgtgttact tactcctccc tgaaaactaa aaacaaatat ttcatcctca
     2281 tgtccctgtt gataccgatt cccgacagag a
//
LOCUS       DAPOXO010000221         2234 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.223, whole genome shotgun sequence.
ACCESSION   DAPOXO010000221 DAPOXO010000000
VERSION     DAPOXO010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2234
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.223"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(390..1862)
                     /locus_tag="ROH59_005123"
                     /pseudo
     CDS             complement(390..1862)
                     /locus_tag="ROH59_005123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
     gene            complement(2014..>2234)
                     /locus_tag="ROH59_005124"
     CDS             complement(2014..>2234)
                     /locus_tag="ROH59_005124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HDX4807478.1"
                     /translation="SGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTES
                     VTIDLAYEGSGSGDWRTDAFIVGIGYRF"
BASE COUNT          391 a          649 c          614 g          580 t
ORIGIN      
        1 gcaacggtcg atttcgcaag aatatcccgc ccaacttttg tcagggttgc cagactggca
       61 acatcattcc ccgtaaaata cggaaacctg tctgccgcag tagcaagccc ggccagcgcc
      121 gtcagggtgg catctttcgg ttgcttaccc gcaagcgcgc tagtcatggt ggtcgcaaaa
      181 ttcgggtcgt tgcccaacgc cgcagccagc tcgttcagcg tattcagtgc gtcaggcgac
      241 gagtccacga gggcagcgat cgcagccata acataagccg tgcttgcgat ttgggtatta
      301 ttcgttccct gtcgcgcagt tggtgttgtt ggcgttccgg tcagtgcagg actatttaag
      361 ggcgctttct tgttcgtttc acccattacc gccttaaccg cttttggcgt tgccgccagt
      421 gactcggaag tgctgttggt cgcactgctg agctgtacta tccccttttt cgtcgtgctc
      481 gcatcctcaa gcgccacggc ggatgcaata tcctctgccc gttttgccgc tgtctcggcg
      541 cgcgttgccg cggattccgc cgtacttttg ctctgagctg ccgccgtcgc actgccagct
      601 gcctctgtcg ccttcgtgga tgccgtcgtg gcgctgccct ttgctgctga cgcctgtctg
      661 gtcgcctcat cttttgaagc agacgcagat gatgccgatg acgccgctga actggctgac
      721 gatgcggctg ccgccttaga ggaagcagca ttgtctgctg aagtctttgc atttgtttca
      781 gaggtttttg ctgcagaagc agacctcgct gctgcagtgg cttgctcagt ggctttgcca
      841 gccttcgttg tggctgttga agcggatgat gcggcgcttt ctgccgattt tccggcggcg
      901 gtggcactgg ctgaggcctg cccggcactt gttgacgcgg cactggcaga taatgcagcc
      961 gctgtttttg aacctgccgc agctgaggcg ctctgtcccg ctgctgtttc agaagactta
     1021 gcgttcgtct cggacgtttt tgccgccttc gcggaatttc ctgccgccgt tgccgaggaa
     1081 gctgcactac tggcacttga tgatgcattc gtttctgaag atttcgctgc ctcttttgag
     1141 gccgccgcac cccgtgccga ggtggcagct tctgacgcct tcgtggtcgc tgtggatgca
     1201 gaagtggctg ccgatttttg tgatgctgcg gcattcgttt ctgacgtttt cgcggcactg
     1261 gcgctggtag ctgccgcgct ttttgatgac tctgcagcag cagcactttt tgctgcttca
     1321 cgggcctttg tcgatgccgt tcctgcgctg gaagacgctg actgagccga cgacgcggcc
     1381 tgtccggctg acgtgctggc ggcacgtgat gaggctgcag catcggttgc atgagttgcc
     1441 gcctcgctgg ctgatgcact ggcatcgctg gctgattttt tcgcggctgc cgtattctgt
     1501 gcaaccgcgg aggcgttacg tgacacctct tctaccatct gctcaaagcg gcgcagtgcc
     1561 tccggtcgta catcatcctc cgtcatggca ccgagaaaat cattcagcgt acctggtctg
     1621 gaaccttcat agacggtaat ggtcccggca tgtgaaggcg gaaaaccttc aaccagcagg
     1681 gtgacgctgt actgaccatg ctcaacatcc atgctgtaac gtccggcttc atccggattt
     1741 tcagaggcca ccgtgttcac caccaccgtg ctgctggttc gtctggcctt cagcacaatg
     1801 gtgcagttct gtactggttt tcctgtgcca tctttaagca cgccagaaat ttttactgtc
     1861 atacttttcc accaataaaa aaagcccgca gcagtgacgc cacgggcttc aggacagtgt
     1921 aactttacgt ttcctcaaac gcagttcacc ccataaggtg gatgaacctg cgtatcataa
     1981 caatatttac agaagataaa tcggcgtctg ttgtcagaaa cggtatccga taccaacaat
     2041 aaatgcatcc gttcgccagt cgccactacc ggaaccttca taagcaaggt caatggtcac
     2101 ggattcggtc gggttaaact gcacgccagc cccccacgcc agagacgtgt tgctgtggcg
     2161 accgtcatca cttccggtca gcacatcgtg cgttttcccc ttgttgtcag ttacgcggag
     2221 ataatccccg gaga
//
LOCUS       DAPOXO010000222         2153 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.224, whole genome shotgun sequence.
ACCESSION   DAPOXO010000222 DAPOXO010000000
VERSION     DAPOXO010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2153
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.224"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            67..450
                     /locus_tag="ROH59_005125"
     CDS             67..450
                     /locus_tag="ROH59_005125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807479.1"
                     /translation="MSVLYIQIRRNQITVRDLESKREVSGDAAFSNQRLLIANFFVAE
                     KVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVAGATLMK
                     YRQFHIHAQSVVLSDSAVMAMFKQK"
     gene            complement(514..957)
                     /locus_tag="ROH59_005126"
     CDS             complement(514..957)
                     /locus_tag="ROH59_005126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDX4807480.1"
                     /translation="MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRAELEELVH
                     SFLPEAPLWVAVNERDQPIGFMLLSGQHMDALFIDPDVRGCGVGRMLVKHALSMAPEL
                     TTTVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGV"
     gene            1114..2043
                     /gene="metA"
                     /locus_tag="ROH59_005127"
     CDS             1114..2043
                     /gene="metA"
                     /locus_tag="ROH59_005127"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDX4807481.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLDPEVPYNYFPHNDPQNKPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
BASE COUNT          554 a          560 c          476 g          563 t
ORIGIN      
        1 aaaaaccccg gtcaataagg ccggggtttt ttgcatatca attatttgca tgatgaaggg
       61 aatctcatgt cagttctgta tatccaaatt cgtcgtaatc aaattactgt tcgcgatctt
      121 gaaagcaaac gtgaagtgtc aggagatgct gccttcagta accagcgcct gttaatcgcc
      181 aatttctttg ttgcagaaaa agttctgcaa gatcttgttc tgcaactcca cccacgttca
      241 acctggcatt cttttttgcc agcaaaacgt atggatattg ttgtgagcgc gctggaaatg
      301 aatgagggcg gtttgtcaca ggttgaggaa cgcattcttc atgaagtggt cgcaggggca
      361 acgttaatga aatatcgcca gttccacatc catgcgcaat cagtggtact cagtgatagt
      421 gcggtcatgg caatgtttaa gcagaaataa tcatgtcacc attggtgggt acgaaaccta
      481 aagttcagcc caccgggatg agaaaaaaac cgcctacacc cccacatatg ccagattcag
      541 caacggatac ggtttcccca aatcgtccac ctcagagcgt cccgtaacct taaagcccac
      601 cttcttatag aacccaaccg cctgctcatt ttgctcatta acagtggttg tcagttccgg
      661 ggccattgag agcgcatgct tcaccagcat ccggcccacg ccgcagccgc gcacatcagg
      721 atcgataaac agcgcatcca tatgctgccc acttaacaac ataaatccaa tcggctgatc
      781 ccgctcatta accgcgaccc acaacggtgc ttccggcaga aaggaatgca ccagctcttc
      841 cagctcggcc cgatactctg ctgataaaaa atcgtgagtg gcatcgacag aacgacacca
      901 aatcgcaacg agttcctccc cctcctcatg ccgtgagcgt cgaatactaa taaccatttt
      961 ctctcctttt cgtcattctt atattctaac gtagcctttt ccttgaaact ttctcacctt
     1021 caacatgcag gctcgacatt ggtaaatttt ctggttatct tcagctatct ggatgtctaa
     1081 acgtataagc gtatgtagtg aggtaatcag gttatgccga ttcgtgtgcc ggacgagcta
     1141 cccgccgtca atttcttgcg tgaagaaaac gtctttgtga tgacaacttc tcgcgcgtct
     1201 ggtcaggaaa ttcgtccgct aaaggtgctt atccttaacc tgatgccgaa gaagatcgaa
     1261 actgaaaatc agtttctgcg cctgctttca aactcacctt tgcaggtcga tattcagctg
     1321 ttgcgcatcg attcccgtga atcgcgcaac acgcccgcag agcatctgaa taacttctac
     1381 tgtaactttg aagatattca ggaacaaaac tttgacggtc tgatagttac cggcgcgccg
     1441 ctgggcctgg tggagtttaa tgatgtcgct tactggccgc agatcaaaca ggtgctggag
     1501 tggtcgaaag atcacgtcac ctcgacgctg tttgtctgct gggcggtaca ggccgcgcta
     1561 aatatcctct acggcattcc taagcaaact cgcaccgaca aactctctgg cgtttatgag
     1621 catcatattc tccatcctca tgcgcttctg acgcgtggct ttgatgattc attcctggca
     1681 ccgcattcgc gctatgctga ctttccggca gcgttgattc gtgattacac cgatctggaa
     1741 attctggcag agacggaaga aggggatgca tatctgtttg ccagcaaaga taagcgaatt
     1801 gcctttgtga cgggccatcc cgaatatgat gcgcaaacgc tggcgcagga atatttccgc
     1861 gatgtggaag ccggactaga cccggaagta ccgtataact atttcccgca caatgatccg
     1921 caaaacaaac cgcgagcgag ctggcgtagt cacggtaatt tgctgtttac caactggctc
     1981 aactattacg tctaccagat cacgccatat gatctacggc acatgaatcc aacgctggat
     2041 taatcttctg tgatagtcga tcgttaagcg attcagcacc ttacctcagg caccttcggg
     2101 tgcctttttt atttccgaaa cacacctcag taagtgaata aattttattt ata
//
LOCUS       DAPOXO010000223         2032 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.227, whole genome shotgun sequence.
ACCESSION   DAPOXO010000223 DAPOXO010000000
VERSION     DAPOXO010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2032
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.227"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..927
                     /locus_tag="ROH59_005128"
     CDS             <1..927
                     /locus_tag="ROH59_005128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HDX4807482.1"
                     /translation="NKLGDLIVLSSIYRELYSKGVKITILTNSKGGAFLSNNKNIFEF
                     CIKESTGFLKMLTLCKHLRDLQFDIVLDPFETMPSFKHSLILSSLKDSYILGFDQWYK
                     RYYSFYHPHDECLKEHMSTRATEILKHIYGEGEFSTDYDLHLPVDVEDKIKEFIGDTR
                     IVIINPLGAKKICRLTFEQIKVIYQEMKLHFENYRVIFTGLPQDLLTIPIPEIETLPF
                     NEFIYTVALTKYSDFVISVDTALVHIAAAYHKPTLAFYPNSRTPEYPSHLIWSPNNHK
                     SIQIVSPTFTVKDIDTETLTDSVKRLSCIDKK"
     gene            complement(953..>2032)
                     /gene="waaL"
                     /locus_tag="ROH59_005129"
                     /gene_synonym="rfaL"
     CDS             complement(953..>2032)
                     /gene="waaL"
                     /locus_tag="ROH59_005129"
                     /gene_synonym="rfaL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase"
                     /protein_id="HDX4807483.1"
                     /translation="RQENYNIKNLILPLSIFLIGLLDLIWYSAFKIDNSPFRATYHSY
                     LNTAKIFIFGSFIVFLTLTSQLKSKKESVLYTLYSLSFLIAGYAMYINSIHENDRISF
                     GVGTATGAAYSTMLIGIVSGVAILYTKKNHPFLFLLNSCAVLYVLALTQTRATLLLFP
                     IICVAALIAYYNKSPKKFTSSIVLLIAILASIVIIFNKPIQNRYNEALNDLNSYTNAN
                     SVTSLGARLAMYEIGLNIFIKSPFSFRSAESRAENMNLLVAEHNRLRGALEFSNVHLH
                     NEIIEAGSLKGLMGIISILFLYFSLFYTAYKRRALGLLILTLGIVGIGLSDVIIWARS
                     IPIIVISAIVLLLVINNRNNTINQE"
BASE COUNT          707 a          334 c          337 g          654 t
ORIGIN      
        1 aataagctcg gtgatctaat tgtattaagt tcgatttatc gtgaacttta tagtaaaggg
       61 gttaaaataa ccattcttac aaatagtaag ggtggggcgt ttctctctaa caataaaaat
      121 atatttgagt tctgtattaa agaatcaacc ggtttcctta aaatgcttac tctatgtaag
      181 catctgcggg atttgcagtt cgatattgta ttagacccct ttgaaaccat gccctcattt
      241 aagcatagtt taatattatc aagtttaaaa gattcttaca ttctgggttt tgatcaatgg
      301 tataaacgtt actattcatt ttaccatccc cacgatgaat gtttaaaaga acatatgagt
      361 acacgagcaa cagaaatact gaagcatatt tatggtgagg gtgaattctc caccgactac
      421 gacttgcatt taccagtaga tgttgaagat aaaataaaag aatttattgg agatacaaga
      481 atagtcatta ttaacccatt aggtgcaaaa aaaatatgcc gacttacgtt tgagcaaata
      541 aaagttatat atcaagaaat gaaactacac tttgaaaatt atcgggtgat atttaccggg
      601 ttaccgcaag atttattgac aataccaata cctgaaatcg aaacactacc atttaatgag
      661 tttatttata ccgttgcgtt gaccaagtat agtgattttg tcatttctgt tgatacagct
      721 cttgttcata tcgctgcggc ttatcataaa ccaacgcttg cattttatcc taattcacgt
      781 actccggaat atccctcaca tttaatttgg tccccaaata atcataaatc aatacaaata
      841 gtatccccaa catttacggt gaaagatatc gatactgaaa ctttaactga ttcagtaaag
      901 agattaagtt gtatagataa gaagtgagtt ttaactcact tcttaaactt gtttattctt
      961 gattaatagt attgttacga ttattaataa cgagtaagag gactatagcg gatataacga
     1021 taattggaat gctgcgtgcc catatgatca catcactgag tccaatcccc acaatgccaa
     1081 gcgttaatat caacaaaccc aaagctcgtc ttttatatgc tgtataaaac agtgaaaaat
     1141 agaggaaaag gatggaaata attcccatca gacctttcag tgaccctgct tcaattatct
     1201 cattatgtag atgtacgtta gaaaactcca atgcccctct tagcctgttg tgttctgcaa
     1261 ctaacaaatt catattttca gcgcgtgact ctgctgatct aaatgaaaaa ggtgacttta
     1321 tgaatatatt taaaccaatt tcgtacattg ccagtcttgc acctagggaa gtcacgctat
     1381 tagcattggt ataactgttt aaatcattta atgcttcatt atagcgattc tgtattggtt
     1441 tattaaatat aattactatg ctagctaata tagcaattag tagaacaata gaggaagtga
     1501 atttcttggg tgatttatta taataagcta ttaatgcagc aacacaaatt atagggaaca
     1561 ggagtagggt tgctctggtt tgtgttagcg ccagaacata aagtaccgcg caactattta
     1621 ataaaaataa aaaaggatgg tttttcttag tataaagaat cgcaacgcca ctaactatcc
     1681 ctattagcat agttgaatat gctgctcctg ttgccgttcc tacaccaaaa gaaatgcggt
     1741 cattttcatg aatgctatta atatacattg catatccagc aattagaaat gacagagaat
     1801 ataaagtgta taatacactc tctttttttg attttagctg gctagttagt gtcaagaaaa
     1861 caataaaaga accaaatata aaaattttgg cagtatttaa ataactatgg taagtagcac
     1921 gaaatggcga attatctatt ttaaacgcag aataccaaat taaatcaagt aagcctatta
     1981 aaaatataga aaggggaaga ataaggtttt ttatattata attttcttgt ct
//
LOCUS       DAPOXO010000224         2002 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.228, whole genome shotgun sequence.
ACCESSION   DAPOXO010000224 DAPOXO010000000
VERSION     DAPOXO010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.228"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            61..495
                     /locus_tag="ROH59_005130"
     CDS             61..495
                     /locus_tag="ROH59_005130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDX4807484.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSRAWGRQEVPSEDARADNPLQRL"
     gene            850..1230
                     /locus_tag="ROH59_005131"
     CDS             850..1230
                     /locus_tag="ROH59_005131"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX4807485.1"
                     /translation="MQKNVTPGRRKGCPNYPPEFKQLLVAASCEPGISISKLALENGI
                     NANLLFKWRQQWREGKLLLPSSESPQLLPVTLDAAAEQPESLAEDPETLSISCEVTFR
                     HGTLRFNGNVSEKLLTLLIQELKR"
     gene            1227..1574
                     /gene="tnpB"
                     /locus_tag="ROH59_005132"
     CDS             1227..1574
                     /gene="tnpB"
                     /locus_tag="ROH59_005132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019104956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX4807486.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTQAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            1624..>2002
                     /locus_tag="ROH59_005133"
     CDS             1624..>2002
                     /locus_tag="ROH59_005133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDX4807487.1"
                     /translation="MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTLTGRVYDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPAAPCCPNCGGS"
BASE COUNT          477 a          521 c          566 g          438 t
ORIGIN      
        1 gtactgcaca cactgccaga ccggaggatt cagtattccc cggacaactc aggaggaaat
       61 atgcgaattc tgaactgtta tatggcgaat gacagcaaag gccattttgt tacggcgaaa
      121 gaagctgcga agcacaaccg acaggacgtt ttgtgctgtg tgtcctgtgg atgcccgtta
      181 acacttcagc ggggcaatga cggacaacca ccgtggtttg aacatgacca gatgactgtc
      241 gctgaaaaaa tcctgctgcg atgtacctgg cttgacccgg cagagaaaga ggcccgtcgt
      301 ttgcatctgc agggcatgac ggttccggat tatacggtga aggtgagaaa gtggttttgt
      361 gtgatgtgtg acgaagatta tgagggggaa aagtgctgcc cacgctgcgg taccggggta
      421 tacagcaggg cgtgggggcg gcaggaggtg ccgtcggaag atgccagggc tgataatccg
      481 ttacagaggc tgtaatggtt gcctccggag cagtttgcgg tgatgccttt cccgggaatg
      541 gattgccagt gcggggactg tggagcttaa ttccggtgtt ggtggccttt ccattgattt
      601 tatgccaaca gccccctgtg actgacaggc tgcctcgtca ttccattcgt atctccagta
      661 acagggggtt gtattgtatt ttattgtacc ggttcaggtg tgcgtttccc ggcgcgtctg
      721 caccggctta accaaattca acagggataa aatagtggta agcgtacagc ctgaaccgtc
      781 tggtcagaat ctgacgaatt agacaaagtg gtgtccacca aataagtagt gggaaccaaa
      841 gtgtcagata tgcagaaaaa tgtgactccc ggcaggcgaa aaggctgccc taattatcct
      901 cccgaattta aacagctgct cgttgctgcc tcctgtgaac ccgggatatc catctcaaaa
      961 cttgctcttg aaaatggcat taacgccaat ctgttgttca aatggcgaca acaatggcgc
     1021 gagggaaagc tgctattacc ttcttcagag agcccccagc tacttcctgt gactctcgat
     1081 gcagctgccg aacagccaga atcgctcgca gaggacccgg aaaccctcag tatcagctgt
     1141 gaggtaacgt tccggcacgg gacgctccgc ttcaatggca atgtcagcga aaagctcctg
     1201 actctgctga tacaggaact gaagcgatga tcccgttacc ttccgggacc aaaatttggc
     1261 tggttgccgg tatcaccgat atgagaaatg gcttcaacgg cctggctgcg aaagtacaaa
     1321 cggcgctgaa agacgatccc atgtccggcc atgttttcat tttccggggc cgcagcggca
     1381 gtcaggttaa actgctgtgg tccaccggtg acggactgtg cctcctgacc aaacggctgg
     1441 agcgtgggcg cttcgcctgg ccgtcagccc gtgatggcaa agtgttcctt acgcaggcgc
     1501 agctggcgat gctgctggaa ggtatcgact ggcgacagcc caagcggctg ctgacctccc
     1561 tgaccatgct gtaaatctct ttatcctggt tgtcacagaa taagcccggt aaaatacggg
     1621 cttatgaacg acatctcttc tgacgacatc ttcctgctaa aacagcgcct ggccgaacag
     1681 gaagcgctga tccacgccct gcaggaaaag ctgagcaacc gggagcgcga aatagaccat
     1741 ctgcaggcgc agctggataa actccgccgg atgaacttcg gcagtcgttc cgaaaaagtc
     1801 tcccgccgta tcgcacaaat ggaagccgat ctgaaccggc ttcagaaaga gagcgatacg
     1861 ctgactggta gggtgtatga cccggcagta cagcgtccgt tgcgtcagac ccgcacccgt
     1921 aagccgttcc ctgaatcact accccgtgac gaaaagcgac tgttgcctgc ggcgccgtgc
     1981 tgcccgaact gcggcggttc ac
//
LOCUS       DAPOXO010000225         1951 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.229, whole genome shotgun sequence.
ACCESSION   DAPOXO010000225 DAPOXO010000000
VERSION     DAPOXO010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1951
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.229"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..899
                     /locus_tag="ROH59_005134"
     CDS             <1..899
                     /locus_tag="ROH59_005134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HDX4807488.1"
                     /translation="FSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLLQT
                     TEDVQFEPCPGLTDAGRGVVSPENIAFTRWLTHLQNGVLLDEQNCLMLHELWLQSGTG
                     QRRWEGLPDEVRETITVHFTAKRGDWCGFWSNEDVSVWWNRLCDNVLPEKTMPFDLLT
                     VLPTRLDVEVNGFNGGVLNGVPSAYHWYTEQYGVKWPVGYEVNISRQGENFIQVDFDT
                     PWCQPESNVVAELSRRFGCTLEHWYAEQGCNFCGWQRYERGELVDVLWGELEWSSPTD
                     DDELPEVTAPEWIVDKVAHYGG"
     gene            903..1207
                     /locus_tag="ROH59_005135"
                     /pseudo
     CDS             903..1207
                     /locus_tag="ROH59_005135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052644.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1284..>1951
                     /locus_tag="ROH59_005136"
     CDS             1284..>1951
                     /locus_tag="ROH59_005136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HDX4807489.1"
                     /translation="MSRFVLGNCIDVMTRIPDNAIDFILTDPPYLVGFRDRSGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPRLPQNPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DDWF"
BASE COUNT          407 a          526 c          591 g          427 t
ORIGIN      
        1 atttttctgg tgaaccggca cagattgctg agattaaacg actggccagc ggtgccgtca
       61 caccgcttta tcgccgcgcc acaaatgaag gtattcagct gtttctggcc ggaagtgccg
      121 gacttctgca gaccactgaa gatgtgcagt ttgaaccgtg ccccggactg acggatgccg
      181 gacgtggtgt tgtatcgccg gagaatatcg cgttcacccg ctggctgaca cacctgcaga
      241 acggtgtact gctggatgag caaaactgcc tgatgctgca tgaactctgg ctgcagagtg
      301 gtactggcca gcgtcgctgg gaaggattac cggatgaggt cagggaaacc atcaccgtgc
      361 atttcaccgc aaaaagaggt gactggtgtg gcttctggag taacgaggat gtatcggtgt
      421 ggtggaaccg tctgtgtgac aatgtactgc cggaaaaaac catgccgttt gacctgctga
      481 cggttctgcc cacccgcctg gatgttgaag tgaatggctt taacggtggt gttctgaacg
      541 gtgttccttc tgcgtatcac tggtatacgg aacagtatgg cgtgaagtgg cctgtggggt
      601 atgaggtgaa tatcagccgt cagggagaaa acttcattca agtggatttc gacacgccgt
      661 ggtgtcagcc ggaaagcaac gttgttgcag aattaagccg ccgtttcggc tgcacgctgg
      721 agcactggta cgccgaacag ggctgcaatt tctgtggctg gcagcgatat gagcgtggag
      781 agcttgttga tgtgctgtgg ggggaactgg aatggtcttc cccgacagat gatgatgagc
      841 tgccggaagt caccgcgccg gagtggatag tcgacaaggt ggcgcattac gggggatgaa
      901 gtatgacgga gacgggcggg caaccgcccg tttcttttcc gacaaaggat gtcgccgtgc
      961 tcctcttttt actgcgccgg ctgacgcggc gcggcaggaa cgctgcctgt ggtcagtgtc
     1021 ccgcgtccgg tgggcacggg acgggcgctt ttactgctcc cggctggcac cggtgacagt
     1081 gtacgccagc ctgtcgccct tttctgatga acgcccttca agccgctttc gcggcatatt
     1141 ctcgccgtca aaaagacgac ggctgcgata ttccacggtc ggcctgaccc gttaccggac
     1201 gcggtgaaca gcccacaggc agcggggaac gggcaccaca ggggggccct cccggtgccc
     1261 tctgtaagag aaggagcgtt gttatgtccc gttttgtcct tggtaactgc atcgatgtta
     1321 tgacgcgtat ccctgataac gccattgatt tcatattaac tgacccgcca tatctcgtcg
     1381 gttttcgtga ccgttccggg cgcaccatcg ccggcgataa aaccgatgaa tggctgcaac
     1441 cggcctgtaa tgaaatgtac cgcgtactca aaaaagacgc gctgatggtg agcttctacg
     1501 gctggaaccg cgtcgatcgc tttatggccg cctggaaaaa tgcgggattc agcgttgttg
     1561 gtcacctggt cttcaccaaa aactacacat cgaaggccgc atatgtgggc tatcgccacg
     1621 aatgcgccta catcctggca aaaggccgtc cacgtctgcc acaaaacccg ctgccggacg
     1681 tgctgggctg gaaatattct ggcaatcgtc atcacccgac ggaaaagccc gttaccagcc
     1741 tgcaaccgct gattgagagc ttcacacacc cgaacgcaat tgtgctggac ccgtttgcag
     1801 gcagcggctc aacctgcgtc gccgccctcc agtccggacg ccggtatatc ggtatcgagc
     1861 tgcttgagca gtatcaccgt gccgggcagc aacgccttgc cgccgtgcaa cgggccatgc
     1921 agcagggggc cgcgaatgat gactggttta t
//
LOCUS       DAPOXO010000226         1931 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.230, whole genome shotgun sequence.
ACCESSION   DAPOXO010000226 DAPOXO010000000
VERSION     DAPOXO010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1931
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.230"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            219..473
                     /gene="bssS"
                     /locus_tag="ROH59_005137"
     CDS             219..473
                     /gene="bssS"
                     /locus_tag="ROH59_005137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415578.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HDX4807490.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFQVNEYRRH"
     gene            588..1706
                     /gene="solA"
                     /locus_tag="ROH59_005138"
     CDS             588..1706
                     /gene="solA"
                     /locus_tag="ROH59_005138"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HDX4807491.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHH
                     GDTRLIRHAYGEGEKYVPLVLHAQMLWDELSRHNEDDPIFVRSGVINLGPADSAFLAN
                     VAHSADQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
                     EAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRK
                     VFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERV
                     PFAEVASDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITG
                     LSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            1754..1867
                     /locus_tag="ROH59_005139"
     CDS             1754..1867
                     /locus_tag="ROH59_005139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HDX4807492.1"
                     /translation="MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF"
BASE COUNT          515 a          457 c          447 g          512 t
ORIGIN      
        1 atttctacac ttactcaaaa taattgcaca atatgctaaa aaaatatgaa tgacatgctg
       61 ttttattgtt catataaatc ttaaaagcag aaatttatct gttccccctt taaaaattcg
      121 gtgaataccc ttacttattg gtatactgaa gttgcttcag ataaaaacgc attgaacctc
      181 gaataacgtt gtctagtaac acgaattagg gggccatgat ggaaaaaaat aatgaagtca
      241 ttcagactca tccgctcgta gggtgggaca tcagcaccgt tgatagctat gatgcgctga
      301 tgttgcgttt gcactaccag accccaaata agtccgagca ggaagggact gaagttggtc
      361 agacgctctg gttaaccact gatgttgcca gacaatttat ttcgatatta gaagcaggaa
      421 tcgccaaaat tgaatccggt gatttccagg taaacgagta tcggcgtcat taacatgaca
      481 tgaccatcca cccaaaaggc acctcaccgg tgcctttacc atttctgggt tgtatatctg
      541 cattcagtta attactctgc ttaaaccatg agagcagaga gaaaaaaatg aaatacgatc
      601 tcatcattat tggcagcggt tccgtaggcg ctgccgccgg gtattatgca acccgcgccg
      661 gtttaaacgt gctaatgacc gacgcccata tgccaccgca tcaacacggc agccaccacg
      721 gcgatacgcg attaattcgc catgcttatg gtgaaggcga aaagtatgtc ccgctggtcc
      781 tccacgcgca aatgctgtgg gatgaacttt cccgccacaa cgaagatgat cccatttttg
      841 tacgctctgg tgtcattaac ctcggtccgg ctgactccgc atttctcgcc aacgtcgccc
      901 acagcgccga ccagtggcaa ctcaacgttg aaaagctcga cgcgcaaggg attatggccc
      961 gctggccaga aatacgcgtc ccggacaact acatcggttt atttgaaact gattccggtt
     1021 ttttgcgcag cgaactggcg attaaaacct ggatccaact ggcgaaggaa gcgggctgtg
     1081 cgcagctgtt caactgcccg gtcaccgcaa ttcgtcatga cgatgatggc gtaactattg
     1141 aaacggcaga cggtgagtat caggcgaaaa aagcgattgt ctgcgcggga acatgggtaa
     1201 aagacctact cccggagctg cctgtccagc ccgtacgcaa agtatttgcc tggtatcagg
     1261 ccgatggccg ctatagcgtg aagaataaat tcccggcatt taccggtgag ctgcccaatg
     1321 gcgatcaata ttatggtttt ccggcagaaa acgacgcgtt gaagattggc aaacataacg
     1381 gaggccaggt tatccattca gcggatgaac gtgttccgtt tgcggaagtg gccagcgatg
     1441 gttcggaagc cttcccgttc ttgcgcaatg tgttgccggg tatcggttgc tgcctgtacg
     1501 gcgctgcctg cacctatgat aattcgcctg acgaagattt tattatcgat accctacccg
     1561 gccacgataa tacactgctc attaccggcc tgagtgggca cggttttaaa tttgcgtcag
     1621 ttttagggga aatagctgcc gattttgcgc aagacaaaaa aagcgatttt gatttgacgc
     1681 cattcaggct ttcccgcttc caataatcat cattacggcc tccagaatga ggccgttttt
     1741 acaggagtat ttaatgcgtc gactgttgca ctatctcatc aataatattc gcgagcatct
     1801 gatgctttat ctttttctct ggggattgtt ggcaattatg gatctgatct atgtgtttta
     1861 tttttagttt tccgcactga cataaactga caaatattta atctcccttt catttagcgt
     1921 gaaaaattga a
//
LOCUS       DAPOXO010000227         1892 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.231, whole genome shotgun sequence.
ACCESSION   DAPOXO010000227 DAPOXO010000000
VERSION     DAPOXO010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1892
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.231"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            291..695
                     /locus_tag="ROH59_005140"
     CDS             291..695
                     /locus_tag="ROH59_005140"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX4807493.1"
                     /translation="MKSLTAVRKKSPNYPVEFKIKMVELSHRPEISVAQLAREHGIND
                     NLLFKWRQYWREGKLRPPSTTENNVPELLPITLDAEDVVPTTSPRSQPVAAATPESLN
                     ISCEVTFRHGSLRLNGAISENILNLLIRELKR"
     gene            692..1039
                     /gene="tnpB"
                     /locus_tag="ROH59_005141"
     CDS             692..1039
                     /gene="tnpB"
                     /locus_tag="ROH59_005141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX4807494.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTTLKDDPMSGHVF
                     IFRGRNGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            1088..>1892
                     /locus_tag="ROH59_005142"
     CDS             1088..>1892
                     /locus_tag="ROH59_005142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDX4807495.1"
                     /translation="MSSSLPDDINALKRLLAEQEALNRALLEKLNEREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLKALQKESDTLTGRVDDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPAALCCPECGGSLSYLGEDAAEQLELMHSAFRVIRTVREKHACTQC
                     DAIVQAPAPSRPIERGIAGSGLLARVLISKYAEHTPLYRQSEMYGRQGVELSRSLLSG
                     WVDACCRLLSPLEEALQDYVLTDGKLHADDTPVPVLLPGNKKTKTGRLWT"
BASE COUNT          454 a          517 c          515 g          406 t
ORIGIN      
        1 tccgggtaat aatattgtta cgcttgccag aaaagccggg tatgagacgt ggtggatatc
       61 aaatcagggc tctttagggc aacatgatac gctgatttct gtcatcgccg ccaatgcgga
      121 taaaaaacat tttcttaagg aagggagctc ttcttccctt cgcattgatg atgaggatat
      181 gcttcagtat gtcagggaag ctgttaattg taagcgtcgt ctcagcaccg tctggcagat
      241 cctgaaattc ctgagagaat agtggacacc aaatatggtg gacgctatcc atgaaatcat
      301 taaccgcagt gcgtaaaaaa agccctaatt atcccgttga gttcaaaatc aaaatggttg
      361 aactctcgca tcgaccagag atctccgtag cgcaactcgc tcgtgagcat gggatcaacg
      421 ataatttgct gttcaagtgg cgccagtact ggcgcgaagg aaaactacgt cctccttcaa
      481 caacagaaaa caacgtgcct gagctgctcc cgataacact tgatgccgaa gatgttgtcc
      541 ctacaacctc cccccggtca caacctgtag ctgctgcgac acctgaatca ctcaatatca
      601 gctgtgaagt gacgttccgg cacggatcac tccgtctgaa tggtgccatc agcgaaaata
      661 tcctgaacct gctgatacgg gagctcaaac gttgatccca ttaccatcag ggacaaagat
      721 ctggctggtc gctggcatca ccgatatgag aaacggcttc aacggcctag cggcaaaggt
      781 gcagacgacg ctgaaagacg atccgatgtc aggtcacgtt tttatcttcc gtgggcgtaa
      841 tggcagtcag gtaaagctcc tctggtctac cggcgatgga ctgtgtctgc tgaccaaacg
      901 gctggagcgc ggccgcttcg cctggccgtc agcccgggat ggcaaagtgt tcctcacacc
      961 ggcacagctg gcgatgctcc ttgaaggtat cgactggcgg cagcctaaaa gactgcttac
     1021 gtccctgact atgttgtaag cctctttatc ctggtcgacg ctgaatgagc ctggtaatat
     1081 acccggtatg agcagctcac ttcctgacga tatcaatgca ctgaaacgtc tccttgccga
     1141 acaggaggcg ctgaaccgtg ccctgctgga aaagctgaac gagcgtgaac gcgaaataga
     1201 ccatctgcag gcacagctgg ataagctgcg ccggatgaac ttcggcagcc gctccgaaaa
     1261 agtctcccgt cgtatcgcac agatggaagc tgacctgaag gcacttcaga aagaaagtga
     1321 tacccttacc ggtcgggttg acgacccggc cgtgcagcgc ccgctgcgtc aaacccgcac
     1381 ccgcaaaccg ttccccgaat cactcccccg cgatgaaaaa cggctgctgc cggcagcgtt
     1441 atgctgcccg gaatgtggag gctcactgag ctatctgggt gaggatgccg ccgaacagct
     1501 ggagttgatg cacagcgcct tccgggttat ccggactgta cgtgaaaagc atgcctgtac
     1561 tcagtgcgat gccatcgtgc aggcccccgc gccttcacgg cccatcgagc ggggtatcgc
     1621 aggatcgggg ctgctggccc gcgtgctgat ctcaaagtat gcagagcaca ccccgctgta
     1681 ccgccagtct gaaatgtacg gccgccaggg cgtggagctg agtcgttcat tgctgtcggg
     1741 ctgggtggat gcatgctgcc ggctactgtc accgctggaa gaagcgcttc aggactatgt
     1801 gctgactgac ggtaagctcc atgctgatga cacgcctgtc ccggtgctgt tgccaggcaa
     1861 taagaaaacg aagaccgggc ggttatggac ct
//
LOCUS       DAPOXO010000228         1760 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.232, whole genome shotgun sequence.
ACCESSION   DAPOXO010000228 DAPOXO010000000
VERSION     DAPOXO010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1760
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.232"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..1678)
                     /gene="hcp"
                     /locus_tag="ROH59_005143"
     CDS             complement(<1..1678)
                     /gene="hcp"
                     /locus_tag="ROH59_005143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HDX4807496.1"
                     /translation="MGDIVYLRIIGEKQGDISSGCGTYASVGNRWQVGHEDEIFAFAL
                     TNAITSTGNGVNLQGLQFCKLIDKSSPLLSNAINQNERLFIEIDLYRINKSGRWERYY
                     YIQLRNASLTAIHVNISDNNLPTECVTVDYDYILCKHLIANTEFDWLAFPAGYNSLFI
                     PPKSPPASNLKPEPLPVVNLPLSSPAVNPVYAKSCLKVKGCTDAGTAEEPAENFGQVA
                     IFVQPVVDDCCGYHHPEANVIGEPAEAQTMLLFPSSVLATQIWGKWSLSGVLSATRGS
                     YIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHGK
                     PQVYGVHTGEGTPYENVRVANMQWNEQTQRYEFTPAHDVDGPLITWTPENPEHGNVPG
                     HTGNDRPPLEQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVY
                     LKEDPRKLPGVVTGHGVPLSPGTRWLDMSVSNNGNGAPIPAHIVDKLRGREFKTFDEF
                     REALWLEVSQEPELIAQFSEINQLRISQGFTPFAPDEGHYIGPKETLKKFQ"
BASE COUNT          456 a          444 c          405 g          455 t
ORIGIN      
        1 tctgaaattt tttaagtgtt tctttaggac caatatagtg tccttcgtcg ggggcaaaag
       61 gtgtaaagcc ctgactaata cgtaactgat taatttccga aaactgcgct atcaactccg
      121 gttcctgact cacctccagc cacagcgcct cgcgaaactc atcaaaggtt ttaaactccc
      181 gtccgcgcaa tttatcaaca atatgcgccg ggattggtgc gccgttgccg ttattggata
      241 ccgacatatc cagccagcga gttcctggtg aaagcgggac gccgtgccct gttacaacac
      301 caggcagctt tcgcggatcc tccttcaggt aaacatagat aggcttaata ccggatcccg
      361 ccggaaaaac cagaatataa tcgttgaatt ctttcggatc aggaaccggg aatggcggcg
      421 tggtataggt atcggtgccg tccggaatcg gcgtcaccag aatggtgggc tgctccagcg
      481 gcggcctgtc gttaccggta tggcccggaa cattcccatg ttccggattt tccggcgtcc
      541 aggtaatcag ggggccatcg acatcgtgag cgggggtaaa ttcataacgc tgcgtctgct
      601 cgttccactg catgttcgcc acgcggacgt tttcatacgg cgtaccttca cccgtatgaa
      661 caccatacac ctgaggcttg ccgtgaatgt cagttcccca gaaaaaacgc acccgggtgg
      721 tggcggtact gcctgctagt gctttctgcc gcagttcttc ctcataccag aactcatcac
      781 gtccaggcac acgagcactg ccctcacccg cagagggaat atacagagca gatgccaacg
      841 caccgatgta agagccgcgg gttgcactga gtacgccact gagcgaccat tttccccata
      901 tttgagtcgc caacacacta ctcgggaaca gtagcatggt ttgagcttct gcgggttccc
      961 cgataacgtt agcctcggga tggtggtatc cacagcagtc atcaaccact ggctgaacga
     1021 aaatcgctac ttgaccgaag ttttcagcgg gttcttctgc cgttccggca tctgtacatc
     1081 ccttcacctt cagacaggat ttggcataga ccgggttaac cgctggtgaa gagagtggaa
     1141 ggttaacaac tggtagcggt tcaggcttaa gattactggc aggtggactt ttaggcggaa
     1201 taaataagct attatagcca gcaggaaagg ccaaccagtc aaattccgta ttggctatga
     1261 gatgtttaca taatatgtag tcataatcga cagttacaca ttcggtagga agattattgt
     1321 cagaaatgtt tacatgaata gcagttaatg aagcatttct tagctgaata taataatacc
     1381 gttcccatcg cccgctttta tttatacgat acaaatcgat ttcaataaat aaccgctcat
     1441 tctgattgat ggcattagac agtagcggtg agcttttatc aatgagtttg caaaattgta
     1501 gcccctgtag attaacgcca ttaccagtac tggtaatggc gttggtgagt gcaaaggcaa
     1561 aaatttcatc ttcatggcca acctgccagc gattaccaac cgacgcatac gtcccacagc
     1621 ctgaagaaat atcgccctgc ttctcaccga ttattctcag gtaaacaata tcgcccactt
     1681 tatttcattc ccgtttatcc ttaacttatt tgcattaaat agaaaactta tttctcgatc
     1741 aataagaaac gcttttaatg
//
LOCUS       DAPOXO010000229         1746 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.233, whole genome shotgun sequence.
ACCESSION   DAPOXO010000229 DAPOXO010000000
VERSION     DAPOXO010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1746
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.233"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1655
                     /locus_tag="ROH59_005144"
     rRNA            <1..1655
                     /locus_tag="ROH59_005144"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          447 a          382 c          547 g          370 t
ORIGIN      
        1 gaatgctgac ataagtaacg ataaagcggg tgaaaagccc gctcgccgga agaccaaggg
       61 ttcctgtcca acgttaatcg gggcagggtg agtcgacccc taaggcgagg ccgaaaggcg
      121 tagtcgatgg gaaacaggtt aatattcctg tacttggtgt tactgcgaag gggggacgga
      181 gaaggctatg ttggccgggc gacggttgtc ccggtttaag cgtgtaggct ggttttccag
      241 gcaaatccgg aaaatcaagg ctgaggcgtg atgacgaggc actacggtgc tgaagcgaca
      301 aatgccctgc ttccaggaaa agcctctaag catcaggtaa catcaaatcg taccccaaac
      361 cgacacaggt ggtcaggtag agaataccaa ggcgcttgag agaactcggg tgaaggaact
      421 aggcaaaatg gtgccgtaac ttcgggagaa ggcacgctga tatgtaggtg aagcgacttg
      481 ctcgtggagc tgaaatcagt cgaagatacc agctggctgc aactgtttat taaaaacaca
      541 gcactgtgca aacacgaaag tggacgtata cggtgtgacg cctgcccggt gccggaaggt
      601 taattgatgg ggttagcggt aacgcgaagc tcttgatcga agccccggta aacggcggcc
      661 gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acctgcacga
      721 atggcgtaat gatggccagg ctgtctccac ccgagactca gtgaaattga actcgctgtg
      781 aagatgcagt gtacccgcgg caagacggaa agaccccgtg aacctttact atagcttgac
      841 actgaacatt gagccttgat gtgtaggata ggtgggaggc tttgaagtgt ggacgccagt
      901 ctgcatggag ccgaccttga aataccaccc tttaatgttt gatgttctaa cgtgggcccc
      961 ttaccggggt tgcggacagt gtctggtggg tagtttgact ggggcggtct cctcctaaag
     1021 agtaacggag gagcacgaag gttggctaat cctggtcgga catcaggagg ttagtgcaat
     1081 ggcataagcc agcttgactg cgagcgtgac ggcgcgagca ggtgcgaaag caggtcatag
     1141 tgatccggtg gttctgaatg gaagggccat cgctcaacgg ataaaaggta ctccggggat
     1201 aacaggctga taccgcccaa gagttcatat cgacggcggt gtttggcacc tcgatgtcgg
     1261 ctcatcacat cctggggctg aagtaggtcc caagggtatg gctgttcgcc atttaaagtg
     1321 gtacgcgagc tgggtttaga acgtcgtgag acagttcggt ccctatctgc cgtgggcgct
     1381 ggagaactga ggggggctgc tcctagtacg agaggaccgg agtggacgca tcactggtgt
     1441 tcgggttgtc atgccaatgg cactgcccgg tagctaaatg cggaagagat aagtgctgaa
     1501 agcatctaag cacgaaactt gccccgagat gagttctccc tgactccttg agagtcctga
     1561 aggaacgttg aagacgacga cgttgatagg ccgggtgtgt aagcgcagcg atgcgttgag
     1621 ctaaccggta ctaatgaacc gtgaggctta accttacaac gccgaagatg ttttggcgga
     1681 agagacatcg ataagtaagc ttgatagcag attaaatcga caggtcataa cgggacgtgt
     1741 tgataa
//
LOCUS       DAPOXO010000230         1736 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.234, whole genome shotgun sequence.
ACCESSION   DAPOXO010000230 DAPOXO010000000
VERSION     DAPOXO010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1736
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.234"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..745)
                     /locus_tag="ROH59_005145"
     CDS             complement(<1..745)
                     /locus_tag="ROH59_005145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDX4807497.1"
                     /translation="MRLTSRFGYVNQIRRDRPLTHEELMHHVPGIFGEDRHTSCSERY
                     TYIPTITVLESLQREGFHPFFACQTRVRDPDRREYTKHMLRLRRNGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLILPPPARQALAQAALTYRYGDEHRPVTTADILTPRRREDYGKDLWS
                     TYQTIQENMLKGGISGRSAKGKRIHTRAIH"
     gene            complement(966..1376)
                     /locus_tag="ROH59_005146"
     CDS             complement(966..1376)
                     /locus_tag="ROH59_005146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807498.1"
                     /translation="MKTFIKTLLVAVTILFSVFAAAKQVKLPNNIKYVNTTEAFSCTE
                     IDGMNCQTKNPFNYKDNSYVFVLERGGAWCYDYTVSVLNLKTGKEQMLEYKDNQLCSG
                     SNKPFFEIKNGVPTVGVIDTSGKPVVVALDKLKT"
     gene            complement(1392..>1736)
                     /locus_tag="ROH59_005147"
     CDS             complement(1392..>1736)
                     /locus_tag="ROH59_005147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807499.1"
                     /translation="YELYEGDAAYKAALDKALKPVGLSGMFGKGGYMDGPGGNVTPVT
                     INGTVWLQGDGCKANTCGWDFIVTLYNPKTHEVVGYRYFGLDDPAYLVWFGEIGVHEF
                     AYLVKNYVAAVN"
BASE COUNT          401 a          438 c          439 g          458 t
ORIGIN      
        1 tgtgaatggc acgggtgtgg atacgttttc cttttgcact gcgaccggaa atcccgcctt
       61 tcagcatatt ctcctggatg gtctgataag tactccacag gtccttaccg taatcctccc
      121 ggcgtcgtgg cgtcagaatg tcggcggtgg tgacgggccg atgttcgtca ccataacggt
      181 aagtcagtgc cgcctgtgcc agcgcctggc gtgccggtgg cggcagaatc agcgactgca
      241 tggcatcacg cttctcctct atccggtcaa acacgcccac cacctcgtaa gccccttcaa
      301 tgactctgtc caccacattt ccccggtgcg gaacacgcac ttcccccaga gactgaccac
      361 agacgcatcc gttctggcag acgaacctga agtaacccgg cagcatctgg tagctggagg
      421 taccgtcatg agagttgagc agaataattt cagggacatg ttctccgttt atctctccgt
      481 tacggcgcag acgcagcatg tgtttggtgt attcccggcg gtccgggtca cgtacgcggg
      541 tctggcaggc gaagaatgga tgaaagcctt cccgctgcag gctttccagt acggtgatgg
      601 tggggatgta cgtatagcgt tcactgcagg aggtatgccg gtcttcaccg aaaatacccg
      661 gtacatggtg catcagttct tcgtgtgtca gcggacggtc acggcgtatc tggtttacat
      721 aaccaaaacg actggttaat cgcatgattt gctccttatc ggtggttaag atttactggt
      781 gtaataaatg aaaaaagcca cgtctcccgg agaagacgcg gcctgacggg tgaaatgaat
      841 gaggtttatt gtctgagaag cctttcactg gcgagccacg cattaagcgg ctttccggca
      901 acaatggctg gggctgtatt tacctttgat attaataatg tgcagagaaa cgcatggttt
      961 actcctcagg ttttaagttt gtccagagcc acaacgacag gttttccgga tgtgtcgatg
     1021 actcctaccg tcggtacgcc atttttgatt tcgaagaacg gtttgttgct acctgagcac
     1081 agctggttgt ctttgtattc gagcatctgt tctttcccgg ttttcaggtt aagtaccgag
     1141 acagtgtagt cgtaacacca ggcaccacca cgttcaagca cgaaaacata gctgttatct
     1201 ttatagttga acggattctt cgtctggcaa ttcataccgt caatctcagt acaggaaaac
     1261 gcctctgtag tattaacgta tttgatgttg tttggcagtt ttacttgttt cgccgcagcg
     1321 aagacagaga acagaatagt tacagcaacg agtaaagttt tgataaaagt tttcatgaca
     1381 gactccttaa attagttaac cgcagctacg tagtttttca ccagatacgc gaattcatgc
     1441 acgccaattt cgccgaacca aaccaggtag gccgggtcat ctaaaccaaa gtagcggtag
     1501 ccaacgactt catgggtttt tgggttatag agtgttacga taaagtccca gccgcaggta
     1561 ttggctttgc aaccgtcgcc ctggagccag actgtaccgt taatggttac tggcgttacg
     1621 tttccgccag ggccatccat atacccgcct ttaccgaaca tgccgctcag tccgaccggt
     1681 tttaatgctt tgtcaagcgc agctttgtag gcagcgtcac cttcgtacaa ctcgta
//
LOCUS       DAPOXO010000231         1730 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.235, whole genome shotgun sequence.
ACCESSION   DAPOXO010000231 DAPOXO010000000
VERSION     DAPOXO010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1730
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.235"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(88..1575)
                     /gene="yeeO"
                     /locus_tag="ROH59_005148"
     CDS             complement(88..1575)
                     /gene="yeeO"
                     /locus_tag="ROH59_005148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001323172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
                     /protein_id="HDX4807500.1"
                     /translation="MWFHFLQLRSALNISSALRQVVHGTRWHSKRKSYKVLFWREITP
                     LAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVV
                     VAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTDVKALA
                     LTYLELTVFSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSW
                     AGLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIG
                     IPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITG
                     RRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILI
                     WLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVG
                     VWMGMFADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEKKPVVSE"
BASE COUNT          540 a          473 c          354 g          363 t
ORIGIN      
        1 ggcgaatatt agcgatgccc acccacaatg tcaaagcctg ttttttaaat ttgaaatcgt
       61 ttgctgaaat aatctgcatt ttgtcgttta ttccgacaca actggctttt tttcacactt
      121 ttgcggctcg gatcgagggt atttccatag ccaacgtcca gtaaccattc gccagtaaaa
      181 cagcacggcc cgcacagccc agtcggcaaa cattcccatc cagacaccaa ccacacccca
      241 gccaagcatg attcccagca cataaccgac tacaacccga caaccccaca tgctcaacat
      301 cgaaacccac atggcgtaac gggcatcacg agcaccttta aatccagcgg gtagcaccca
      361 tgaggcggac caaataggca taaataaagc atttagccaa atcagaatca caacgacgtg
      421 tttaacctgt ggatcctggg tgtaaaacga tgccataacc ccggcaaagg gagccgttag
      481 ccaggcgatg gccgttaatc caagagtgga cagccagaac acatgccgca actgaatctc
      541 tgcttgcgct atctgcccta cccccaacct tcggcctgta atgatcgtag aagcagaacc
      601 gagcgcactt ccgggtaagt tgataagagc cgcaattgag aacgcgataa aatttccggc
      661 aataacgctg gtccccatcc cggcaacgaa catttgggtt aataaccgac cactggtaaa
      721 taacactgat tcgacactcg ctggaatacc aatccccatg acttcccaga taatgctaaa
      781 attcagcggt ttaaaatagc tctttaacga aatccttagc gcaggattaa aaccaatcgc
      841 cagcacccac aaaattgcaa ctgcgccaat ataacgagaa atggttaaac ccaacccagc
      901 cccgacaaat cccagtcccg cccaggagaa aaggccgtaa atcaatatgc cgctaataat
      961 aatattaaga atattcaggc taccgttaat cagtagcggt attttcgtat tccctgcacc
     1021 acgaagtgcc ccgctaccaa taagagtgat ggcagctgct ggataactga atacggtcag
     1081 ctccagataa gtcaacgcca gtgctttaac gtctgtcgtg gcatcacccg cgacgaaatc
     1141 aataatttgt tcgccaaaat gatgaattag cgttgccaac agtacggcaa acaacgtcat
     1201 gatcaccaat gactgccgcg tcgccaccct cgctcgtcgt cgatctcgct taccgagact
     1261 aaatgctaca acgacagtag taccaagatc gatagctgca aaaaaagcca taatgaccat
     1321 attgaagctg tccgccaacc ccacgccggc catcgcatct tttcccagcc agctgaccag
     1381 aaaagtgctc aggaccccca tcaacaggac acaggcgttc tccatgaaga taggaacagc
     1441 aagcggggtt atctcgcgcc agaacaacac tttgtagctc ttgcgtttag agtgccagcg
     1501 agtgccgtga acaacctggc gtaaagcaga ggagatattc aaagccgacc ttaattgcag
     1561 aaagtgaaac cacatttcaa atgatgaggg agaatcagca aagctgcaaa gattttcgcc
     1621 aacaaattgt ctgcaaatgc aacaaactgt tgatagaaac ggcaaacagt tgggaaattt
     1681 aaaaatcggg tttgacaaaa tatttttcgc cgttaagatg tgcctcaaca
//
LOCUS       DAPOXO010000232         1713 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.236, whole genome shotgun sequence.
ACCESSION   DAPOXO010000232 DAPOXO010000000
VERSION     DAPOXO010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1713
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.236"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..411
                     /locus_tag="ROH59_005149"
     CDS             <1..411
                     /locus_tag="ROH59_005149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HDX4807501.1"
                     /translation="CRELAAKYPGDAPLMLVIWSPEEIQALADGMEISLTDHEIRTVL
                     ARMEDIPEDQRTESGISSAAVMEIISNVSENRQVTVPAELLASLIQTAEQALWKREWA
                     ARDNGLAVPECVTRRQAVVNQARTLLKNNTHENN"
     gene            462..1238
                     /locus_tag="ROH59_005150"
     CDS             462..1238
                     /locus_tag="ROH59_005150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807502.1"
                     /translation="MNENSTLNALICRHARNLLLAQGWPEETDVDQRNPNYPGWISIY
                     VRLDAPRLATLLINRHGGVLPPLLASAIQRLTGTGAELVLSGSQWQSLPVLPADGTQV
                     SFPYAGEWLTEDEIRAVLDAVHDAVRSICYQVAEDARRIRAALTTTGQTLLTRQTRRF
                     RLVVKESDHPCWLDEDDENLPVVLDAIVNRGARFSSVEMYLVSECIEHILSSGLACDV
                     LRIPDEPPRRWFDRGVLREVVREARTEIRSMADALAKIRK"
BASE COUNT          328 a          510 c          524 g          351 t
ORIGIN      
        1 tgccgggagc tggcagcaaa gtatccggga gacgcgccgc tgatgctggt tatctggtcc
       61 ccggaagaga ttcaggcact ggctgacggt atggaaattt ctctgaccga tcatgaaatc
      121 aggaccgtcc tggcgcgcat ggaggacatc ccggaagacc agcggactga atccggtatt
      181 tcttccgccg cggtgatgga gattatcagc aacgtgagcg aaaaccgcca ggtgaccgtc
      241 cctgctgaac tgctggcgtc cctgattcag accgctgaac aggcactgtg gaaacgtgag
      301 tgggccgccc gtgataacgg cctcgccgtc ccggaatgcg ttacccgccg tcaggcggtg
      361 gttaatcagg cccgcaccct gctgaaaaac aacacacacg aaaacaactg atgttatcgc
      421 cgcctgccct gcgggcggcg atacagggag aacgcttaat catgaacgaa aacagcacgc
      481 tgaacgcact gatttgtcgt cacgcccgta acctgctgct ggcgcagggc tggccggaag
      541 agacggatgt tgaccagcga aatccgaact atccgggctg gatcagcatt tacgtgcggc
      601 tggatgcgcc ccggctggcg acgttactta tcaaccgtca cggcggcgta ctgccgccgc
      661 tcctggcctc cgccattcag agactgaccg gaaccggggc ggaactggta ctgtccggca
      721 gtcagtggca gtcgctgccg gtacttccgg cagacggaac gcaggtgtct ttcccgtatg
      781 ccggagaatg gctgaccgaa gacgaaatca gggctgttct tgatgcggtg cacgatgcgg
      841 tacgaagcat ctgttaccag gtggcagaag atgcgcggcg tatccgtgcg gcgctgacca
      901 ccaccggtca gacgttgctg acccgccaga cgcgccgctt tcgcctggtc gtgaaggaaa
      961 gcgatcaccc ctgctggctc gatgaagatg acgaaaacct gcccgtggtg ctcgatgcca
     1021 tcgtgaaccg gggagcacgt ttttcgtcgg tggaaatgta tctggtcagt gagtgtattg
     1081 agcatatcct gtccagtggg ctggcctgcg atgtgctgcg tataccggat gaaccgcccc
     1141 gccgctggtt tgaccgtggt gttctgcggg aggtggtccg ggaagcccgg accgaaatcc
     1201 gcagcatggc ggatgccctg gcaaaaatcc ggaaatgatg acactggcgg ggtaaatccc
     1261 cgcctttttc ctgccggtcc ccggacagag cacaaaggaa gtcgccgccg gctccgcttt
     1321 acccggccat gcagggcatg gccttgtggt ttttcagtta tgtggcctca gcgtcgtgtg
     1381 cgggctgtgc cgtgcctcca tcttagccgg gctggcgttg atgcaagggt acgcttcgcc
     1441 gctgcggtca cccggtccct ccttcccgtc tgccgtgatt ttccggtcgt tcacccgctc
     1501 agatttcgcg gtctcaccct gcaactcccg tcagccgtgt gcgtcaggct gcggcttccc
     1561 ttgcgcccct gcatccccgc ctgttcgccc ggcttttatg gaggcacggc accgcccggt
     1621 gtcgcggaat atgtgaacaa cggaggaaaa catcatgcaa tatgcgaaac ctgtcactct
     1681 gaatgttgaa gagtgcgacc gtctctcctt tct
//
LOCUS       DAPOXO010000233         1702 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.237, whole genome shotgun sequence.
ACCESSION   DAPOXO010000233 DAPOXO010000000
VERSION     DAPOXO010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1702
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.237"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..411
                     /locus_tag="ROH59_005151"
     CDS             <1..411
                     /locus_tag="ROH59_005151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDX4807503.1"
                     /translation="CRELAAQYPGNTPLMLVVWSPEEIQALADGMDIALTDHEIRTVL
                     ARLEDIPEDQRIESGISSAAVMEIIRNESENRLVTVPAELLASLIQTAEQALWKREWA
                     ARDNGLAVPECVTRRQAVVNQARALLKNNTREND"
     gene            456..1226
                     /locus_tag="ROH59_005152"
     CDS             456..1226
                     /locus_tag="ROH59_005152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807504.1"
                     /translation="MNETLNALICRHARNLLLAQGWPEETDVDQRNPNHPGWISIYVR
                     LDAPRLATLLINRHGGVLPPHLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVSF
                     PYAGEWLAEDEIRAVLAAVRDAVRCVSYQVADDARRIRAALTTTGQTLLTRQTRRFRL
                     VVKESDHPCWLDEDDENLPVVLDAIVNRGARFSAVEMYLVSECVEHILSSGLACDVLR
                     IPDEPPRRWFDRDVLREVVREARAEIRSMADALAKIRK"
BASE COUNT          316 a          511 c          528 g          347 t
ORIGIN      
        1 tgccgtgagc tggcagcgca gtatccggga aacacaccgc tgatgctggt tgtctggtcc
       61 ccggaagaga ttcaggccct cgctgacgga atggatattg cccttaccga tcatgaaatc
      121 agaaccgtcc tggcgcgcct ggaggacatc ccggaagacc agcggattga gtccggtatt
      181 tcttccgctg cggtgatgga gattatccgc aacgagagcg aaaaccgcct ggtgaccgtc
      241 cctgctgaac tgctggcgtc cctgattcag accgctgaac aggcactgtg gaaacgtgag
      301 tgggccgccc gtgataacgg cctcgccgtc ccggaatgcg tcacccgccg acaggcggtg
      361 gttaatcagg cccgcgccct gctgaaaaac aacacacgcg aaaacgactg atgttatcgc
      421 cgcctgcggg cggcgattca gggagaccat gaatcatgaa cgaaacgctg aatgcactga
      481 tttgtcgcca cgcccgtaac ctgctgctgg cgcagggctg gccggaagag acggatgttg
      541 accagcgaaa tccgaaccat ccgggctgga tcagcattta cgtgcggctg gatgcgcccc
      601 ggctggcgac gttacttatc aaccgtcacg gcggcgtact gccgccgcac ctggcctctg
      661 ccattcagaa actgaccgga accggggcgg aacttgttct gtccggcagt cagtggcagt
      721 cgctgccggt acttccggca gacggaacgc aggtgtcttt cccgtatgcc ggtgagtggc
      781 tggcagaaga cgaaatcagg gctgtacttg cggcggtgcg cgatgcagta cgctgtgtca
      841 gttaccaggt ggcagacgat gcgcggcgta tccgggcggc gctgaccacc accggtcaga
      901 cgttgctgac ccgccagacg cgccgctttc gtctggttgt gaaggaaagc gatcacccct
      961 gctggctcga tgaagacgac gaaaatctgc ccgtggtgct cgatgccatc gtgaaccggg
     1021 gagcacgttt ttcggcagtg gaaatgtacc tggtcagtga gtgtgtggag catatcctgt
     1081 ccagtgggct ggcctgcgat gtgctgcgta taccggatga accgccccgc cgctggtttg
     1141 accgtgatgt tctgcgggag gtggtccggg aagcccgggc cgaaatccgc agcatggcgg
     1201 atgccctggc aaaaatccgg aaatgatgac gttggcgggg taaatccccg cctttttcct
     1261 gccggtcccc ggacagagca caaaggaagt cgccgccggc tccgctttac ccggccatgc
     1321 agggcatggc cttgtggttt ttcagttatg tggcctcagc gtcgtgtgcg ggctgtgccg
     1381 tgcctccatc ttagccgggc tggcagggat gcaagggtac gcttcgccgc tgcggtcacc
     1441 cggtccctcc ttcccgtctg ccgtgatttt ccggtcgttc acccgctcag atttcgcggt
     1501 ctcaccctcc aactcccgcc agccgtgtgc gtcaggctgc ggcttccctt gcgccctgtg
     1561 catccccgcc ttatcgcccg gcttttatgg aggcacggca ccgcccggtg tcgcggaata
     1621 tgtgaacaac ggaggaaaac atcatgcaat atgcgaaacc tgtcactctg aacgttgaag
     1681 agtgcgaccg tctctccttt ct
//
LOCUS       DAPOXO010000234         1701 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.238, whole genome shotgun sequence.
ACCESSION   DAPOXO010000234 DAPOXO010000000
VERSION     DAPOXO010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1701
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.238"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..447
                     /locus_tag="ROH59_005153"
     CDS             <1..447
                     /locus_tag="ROH59_005153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kfiB protein"
                     /protein_id="HDX4807505.1"
                     /translation="ISEKEQILKQLHIVQEQLEHYFIENQEIKKKLPPVLYGAAEQIK
                     QELGYRLGYIIVSYSKSLKGIITMPFALIRECVFEKKRKKSYGVDVPLYLYADADKAE
                     RVKKHLSYQLGQAIISSANSIFGFITLPFKLIVLVYKYRRAKIKGC"
     gene            complement(544..1578)
                     /locus_tag="ROH59_005154"
                     /pseudo
     CDS             complement(544..1578)
                     /locus_tag="ROH59_005154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178350.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS481 family transposase"
BASE COUNT          461 a          308 c          358 g          574 t
ORIGIN      
        1 atatcagaaa aagaacagat tttaaaacaa ttgcatatag tgcaagagca gttggaacac
       61 tattttatag aaaatcagga aattaaaaag aaacttccac ctgtgctata tggagcagct
      121 gagcagataa aacaagagtt aggttatcga cttggttata ttatagtctc gtattctaaa
      181 tccctcaagg ggattattac catgccattt gcacttatcc gtgagtgtgt ttttgaaaaa
      241 aaacgtaaga agagttatgg cgttgatgtg ccactctatt tatatgctga tgctgataag
      301 gctgaaagag ttaagaaaca tttatcttat caattagggc aggctattat ctccagtgct
      361 aattcgatat ttggattcat tacccttcca tttaagttaa ttgttcttgt ttataaatat
      421 aggagagcta aaatcaaggg ctgttaaaaa tgtgaaccct aatgagatat attgcaaatt
      481 ttatttttct ctttgtggtg ttttgctttc gttaaaatag ttagttattt tatttatata
      541 atatcacgca ttataatacc aatttatact tttgcaagtg accgtataga ttcgccacat
      601 attgcaaatt ttgttctctc gtaaaatatt ttcttctggt gtcagtaatt cgagcacttc
      661 atgctgtctt ttactgcagt atagtactag gttttcagct agtttctgat taaatatgtt
      721 tagctcttta aagagtctat ttatttaaat tcaatgaact gttctttcgg cgttcgctta
      781 aaacgttcag aggtgcgttc taggcgtaaa ggggtaggtc catagggctt gctagcggat
      841 tcctgcggtg ctttgtcgaa gtttcctggg aactctttcc cgttatctgc gatgccctgg
      901 ttgatatcga tagggaatag ccggtctgca cggcaaaaga agagtttgat gatatcacag
      961 ttaagtgacg gcacggcctg tgccagagcg tagttgctgt gttcgtcgat catggtaatg
     1021 acataacagc gcagctcgcc cattctgagc tcaatagcat ctataccaac gagctcactg
     1081 ctctttaccg ggcgatagcg ttttgatctg cgggttggag gattgtattt tttatgaaca
     1141 gtgtttttcc ttggggaggc agtcacatcg gtatcagtcg cattttatcg tgtgcggccg
     1201 tgaacatcct gccgatggtt gaaatgctcg gacagaccag gcggtgctgt tcactccacg
     1261 gcttcaagca aacaaaaatc tgttcttcta ggttgggaag ctctattctc agtcgacgta
     1321 tttcttacag aattacgaga tgccattgct ttgtgcgatg tactagcgga gctttgctac
     1381 gcgaaatagg tgcctctggg ccataataca gcgttcgtgt ggatacagca aaaacttccg
     1441 caactgtatt gatctcatgt ttctcccaga agtatatttt ttcatcctta attttgtaat
     1501 ctcaggtata acaaagtgtt tcatcacata gatgttggca tggtaatgcc tcaaatatcc
     1561 gccgcagata cgttgcatca acttagcatt tccctcgctt gtccggagat aattgcaata
     1621 tctctgtgag cttacactgt gacattcgtt gagttttagt gatgttttta aagatttata
     1681 tttataatat ttagtaaatg c
//
LOCUS       DAPOXO010000235         1694 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.239, whole genome shotgun sequence.
ACCESSION   DAPOXO010000235 DAPOXO010000000
VERSION     DAPOXO010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1694
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.239"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(82..207)
                     /locus_tag="ROH59_005155"
     CDS             complement(82..207)
                     /locus_tag="ROH59_005155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807506.1"
                     /translation="MEIKVQRPSLWMINTVFLLLPINNHQTNTIKLIFEMCSLDF"
     gene            complement(260..664)
                     /locus_tag="ROH59_005156"
     CDS             complement(260..664)
                     /locus_tag="ROH59_005156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HDX4807507.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHIRGKSTFREYCSTLAGAGVFR
                     WVTDVNHNKRSYYAIDNTLLYIEDVENNKPLI"
     gene            complement(885..1616)
                     /gene="bluR"
                     /locus_tag="ROH59_005157"
     CDS             complement(885..1616)
                     /gene="bluR"
                     /locus_tag="ROH59_005157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor BluR"
                     /protein_id="HDX4807508.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTRQDTQDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
BASE COUNT          459 a          369 c          357 g          509 t
ORIGIN      
        1 tctgcatgtg ttaaaaacgg taacgggcgt ataacacgcc cgttgttgtt ataaatatgt
       61 taaccattat aaaataacgt atcaaaagtc aagtgaacac atttcaaata tcaatttgat
      121 cgtattggtc tggtgattat ttatgggaag caataaaaag acagtattaa tcatccatag
      181 ggatggtctc tgcactttta tttccattat gctaatgcct tactgaatta tgaagcattt
      241 cttaagctcc caactttagc tagattaatg gtttattatt ttctacatct tcaatatata
      301 aaagcgtatt atcaatggcg tagtaactgc gtttgttatg attaacatca gtaacccacc
      361 ggaaaacgcc tgcgcctgcc agtgttgaac agtattcccg aaatgtagat tttccgcgaa
      421 tatgaagcaa tgcggcctct tttattttag ctgggttctt ggtcgtacta acttttaaca
      481 ggttcctggt tcctcttaat aacaaaaccg tgtcatcgtg agtaataatt ctgatgttat
      541 ccgtagccag ataataaatg taatgtgcaa tacggtgatg ttttaattct gaataaaacc
      601 aggagaagtt ttgctctttt ctcacttgct caaacatctt ttgaaaaaca acgacctgat
      661 ccatcaggat aataacctct tgttaggtgt gagactgcgt agtgtgcacg atcggtttta
      721 ccacttcaat ctggtctgtc ctttggctgt gatatgtaca aagtgtcaaa gggggattac
      781 ctgaattctc ccggtgagca ttttgcaacg gaccagctcc gctacaaacg ctgttgtggg
      841 ttcagattat aacattctgt ctaaggggcg ggataaaggt gaatttaggg ggcatgaaag
      901 atgactttat aaccttgctc accccagtgt tgtaaaagtt cgttttgcct tctcgttggt
      961 gccatgcctg tccagacaat caatgtttgc gttgggaaca gttccgggcg cggcgattca
     1021 atgggatcag caagaacaga aatgtgccat cctgacaatg ataaacgcca tgcttccagc
     1081 cacaatcgtg ctctctcttc aacattccac gccatcagaa tggcctcttt accgggctta
     1141 cggcgcattt cgaaaagtga ggccgctgcg tattcaatta atgcgccgtc aaacatactg
     1201 ctcataatgc gggaggtgtt gtgatcaagc acgagacgct ggcgaacagg aaggtaaaca
     1261 tgattaatca attgatctac tgggtactct cgacccagtg aaataattcg cgcgcgtagt
     1321 ttggctggat tagccatacg aagaattgac atcatctctt cttgcaggcg gctccagtca
     1381 tcttgcgtat cctggcgggt agtttccagt aatgctttaa ctttgcctac aggaacgcca
     1441 ttacttatcc aacgcttgat ctcttcgatg cgttgtatgt cttcttcatc aaagagtcgg
     1501 tgtccgcctt cactgcgttg tggttttaac aaaccgtagc ggcgttgcca ggcccggaga
     1561 gtgacaggat taatcccgca acgttcagca acatcaccaa tgctgtaata agccacaatt
     1621 cctccttgcg gtcataaatc tccgtcgcct ctacacgacc caataatact ttgtacaata
     1681 tacgctaaaa ttgt
//
LOCUS       DAPOXO010000236         1682 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.240, whole genome shotgun sequence.
ACCESSION   DAPOXO010000236 DAPOXO010000000
VERSION     DAPOXO010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1682
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.240"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..353
                     /locus_tag="ROH59_005158"
     CDS             <1..353
                     /locus_tag="ROH59_005158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807509.1"
                     /translation="EFIRGWDDGRKVDTGRKLLSAQGATLLRTAMLDYYNQDTTGTSG
                     IVGMGFNNEDSITDLREGSFKMPDGTTFSDPVVAMSDNGMQATILTSIRSGYAKGITV
                     RPRSIALNYIVRAV"
     gene            353..967
                     /locus_tag="ROH59_005159"
     CDS             353..967
                     /locus_tag="ROH59_005159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX4807510.1"
                     /translation="MSNTAVLDENGIATVAGDITVYHYDEETREYTSSSVEYLALGVG
                     TPAHSCADAPPEAISGYVVCRTATLNGWEHVPDHRGETVYSTENGNPVLITQPGDYPA
                     DTTTKQPATPWDTWNGEAWVTDTERQRAAELEVARQQRQQRVKQAMASVDLINLKLRA
                     GRSLKPEETAKLNAVLDYIDELNALDISKAPEISWPEAPLALAG"
     gene            complement(974..1435)
                     /locus_tag="ROH59_005160"
     CDS             complement(974..1435)
                     /locus_tag="ROH59_005160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001491734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HDX4807511.1"
                     /translation="MGEGSALPVGVPVPWPTATPPAGWLQCNGATFTKEQYPVLVRVY
                     PTLRLPDLRGEFIRGWDGGRKVDTGRALLSFQEGTIVSGFDDNDTGDISSLGSTQYGF
                     GDALTSNQLGVLNGKKWIFDASSKGAQRYDWWAYVSARPRNIAFNYIVRAA"
BASE COUNT          451 a          429 c          446 g          356 t
ORIGIN      
        1 gtgagtttat ccgtggatgg gacgacgggc gcaaagttga tacaggacgt aagttgctgt
       61 ccgcacaagg ggcaacgctg ttaagaacag caatgctgga ttattataac caggacacta
      121 cgggaacctc ggggatagtc ggcatgggat tcaacaatga agattccatt acagaccttc
      181 gtgagggcag ctttaaaatg ccggacggga caacattcag cgatcctgtc gtggcaatgt
      241 cagacaatgg tatgcaggct actattctga cctctatcag aagcgggtat gcgaagggta
      301 tcactgtcag accccgtagc attgcactta attacattgt gagggcagtt taatgagtaa
      361 cactgcagtt ctggatgaaa acggtatcgc cactgtagcg ggcgatatca ctgtatatca
      421 ctatgacgag gaaacccggg aatacacctc atcctctgtg gagtatctcg cccttggggt
      481 gggtactccg gcacattcgt gcgccgatgc accgccggaa gcaatttcgg gttacgtggt
      541 ttgccggact gccacgctga acgggtggga gcatgtgcct gatcaccgcg gcgagacggt
      601 atacagcacg gagaacggta accccgttct gattacccaa ccgggtgatt acccggcgga
      661 caccaccaca aaacagccag ccacgccatg ggatacctgg aacggtgagg cgtgggtaac
      721 cgatactgaa cggcagcgag ccgcagaact ggaggttgcc agacagcaac gccagcaacg
      781 ggtgaaacag gcgatggcgt ccgtcgatct tatcaacctc aaactgcgtg ctggtcgcag
      841 tctgaaacca gaagaaacgg caaaactgaa cgccgtgctg gattatatcg acgagctgaa
      901 cgcactggat atcagcaagg cacctgaaat cagctggccg gaagcgccac tggcgcttgc
      961 cggctgaacg gtatcacgcc gccctcacga tatagttaaa tgcgatattg cgggggcgag
     1021 ctgatacata agcccaccag tcatatcttt gtgcaccttt agaggatgca tcaaatatcc
     1081 actttttgcc atttaagacc cccagttgat tagaggttaa agcgtcacca aatccgtatt
     1141 gtgtagagcc gagcgaactg atatctccgg tatcattatc atcaaaaccg gatacgatag
     1201 tcccttcctg aaatgaaagt agcgcacgcc cggtatcaac cttgcgacca ccgtcccatc
     1261 cacggataaa ctcaccgcgc aaatcgggaa gacggagggt cgggtagact ctgaccagaa
     1321 caggatattg ttctttggtg aacgtagctc cgttgcactg taaccagcct gctggcggtg
     1381 tggcggtggg ccatggaacc ggtacaccaa caggcaatgc agagccttcc cccaaaccaa
     1441 cgtttctatg ccgcccttac gatgtaatta aacgcaatgt tacggggacg aatggtcaca
     1501 taattaaccc catcgcctcg cgaaggacct gcaaatgaaa aacgggagaa tccaggttgg
     1561 ttgtcaacga tttggtcata gttattgatt gaatgaccag acccaatgtc aaaattacct
     1621 gcgtaatgag aaaaacttgt accatcctgc cgtgaaagca gatcgcgccc tgtatccact
     1681 tt
//
LOCUS       DAPOXO010000237         1639 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.241, whole genome shotgun sequence.
ACCESSION   DAPOXO010000237 DAPOXO010000000
VERSION     DAPOXO010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1639
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.241"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            447..764
                     /locus_tag="ROH59_005161"
     CDS             447..764
                     /locus_tag="ROH59_005161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807512.1"
                     /translation="MTFQTTITEVCSYIGDNWMIDPHPPQELLEGYFHLISKEYENQH
                     FSMYGFIMNETLYIKGCVFNELNGDMIHIPLNKDYREIARLIKCKVISQKKYLFAVVR
                     NRT"
     gene            831..1160
                     /locus_tag="ROH59_005162"
     CDS             831..1160
                     /locus_tag="ROH59_005162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807513.1"
                     /translation="MKNMSYAEHVAQTILGQLGSQRFVVMTGAKNLAYFDDNGECGLC
                     FQLPSYFAKNNINIVRIKLTFADDYTVTFYSKQGSRIAQISEREGIYCDQLQWLFTRE
                     TGLYTRL"
     gene            1242..>1639
                     /locus_tag="ROH59_005163"
     CDS             1242..>1639
                     /locus_tag="ROH59_005163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDX4807514.1"
                     /translation="MSKKKTTTTPTPHDAAFRSFLANPDIARDFLELHLPAEYRQLCD
                     LSTLKLEPATFVEPDLHQYASDILWSVKTTGGEDGYVYTLIEHQSTENLYMPFRMLRY
                     SVAAMQRHLEQHKTLPLVIPVLFYHGERSP"
BASE COUNT          449 a          362 c          419 g          409 t
ORIGIN      
        1 gcgggagaaa ccccgaagaa gtggacggca gaaggagctt cgctcctgtg aagatgcctg
       61 aacataccgt gccgctcttt aacaacctga ccatttttta gcgaacagaa acaacccagt
      121 gaaggaggtg agaacgatgt aaatcacgca cagcgtgagg gaatgccggg aaggaaaagg
      181 aggttagtgg gtgtgccagg gggtgggaac acccctttgc acggatatca acaacctttg
      241 taaggatatt gattatgtca ctcagacaaa tcgtaaccct tgctgatgcg gttgtcaaag
      301 gacaacccac acgcattccg ccaatgaaag gcgacgaatg gcacgagttc tgttggtggc
      361 tggaccacct cagaggctac gccatgtgat accagggggc ggaaacgccc catttcacat
      421 cataagtttt tacttcaggg ggtaacatga catttcagac aacgataaca gaagtatgtt
      481 catatattgg tgataactgg atgattgatc cacatccccc gcaggaactg ctggagggat
      541 attttcactt aatcagtaaa gagtatgaaa atcagcattt ttcaatgtat ggttttatca
      601 tgaatgagac gttatatata aaagggtgcg tttttaatga actgaacggg gacatgattc
      661 atattcctct taataaagac tacagggaaa tagcccgttt aataaaatgc aaagttataa
      721 gccagaaaaa atatctcttt gcagttgtgc gtaacagaac ttgagtcccc aattatcagt
      781 gtcgcaggta gtcgtgtctc ctgcggcata tctctcgtca ggatattaga atgaagaata
      841 tgagttatgc tgaacatgtc gctcaaacaa ttctcggaca gctggggagc cagcgatttg
      901 ttgttatgac cggcgctaaa aatctggctt attttgatga taatggtgaa tgcggtttat
      961 gctttcagtt accgtcatat tttgcgaaaa ataatattaa tattgtccgg atcaaattaa
     1021 cgtttgccga tgattacacg gtgacgtttt acagcaaaca gggttcccgg atagcgcaga
     1081 tatcggagcg cgaggggatt tattgcgatc agctgcagtg gctttttacc cgggagaccg
     1141 ggctgtatac acgactgtaa atctgttccc ttctttctgc ccgtggcagg tgcgtaccgc
     1201 acgggcgtat aattccggtg ataataactc atggagggaa agtgagtaag aagaaaacca
     1261 ccacaacgcc cacgccgcat gatgccgcgt tccggtcgtt cctggcgaat cccgacattg
     1321 ccagggattt tctggaactg catcttcctg cggagtaccg gcagttgtgc gacctgtcca
     1381 ccctgaagct ggaacccgcc acctttgttg agccggacct gcatcagtac gccagcgata
     1441 tcctctggag cgtgaaaacc accgggggtg aagatggtta tgtttatacg ctcatcgagc
     1501 accagagcac agaaaatctg tacatgcctt ttcgcatgtt acgttacagt gtggcggcga
     1561 tgcagagaca tctggagcag cacaaaacgt tgccactggt cattccggtg ctgttctatc
     1621 acggtgagcg cagcccgta
//
LOCUS       DAPOXO010000238         1443 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.242, whole genome shotgun sequence.
ACCESSION   DAPOXO010000238 DAPOXO010000000
VERSION     DAPOXO010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.242"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            118..915
                     /locus_tag="ROH59_005164"
     CDS             118..915
                     /locus_tag="ROH59_005164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807515.1"
                     /translation="MNTQLLKVGQCLKHLNDDVAVSEVTLSDGEISYTLLNLELPTAF
                     TVEQARISARFGWTLTDKTLSLDEIRSRREVVRVCKQRRDEEAARKAEEEQRSREQVS
                     TNPEYQDLLTKKDEPSTTKLAAKNIRLLLKKHFKGIKFSVRMRDYSCINVGWTDGPTT
                     DEVDAVISRFQEGRFDGMTDMYEYGNDPFNKVYGGVQYLFTSRECSDALIEEAIASVK
                     TRYKSVVGDDCTVAAFRSGKLWNVGNEYFSHGLQSAIHQAAAAISKK"
BASE COUNT          349 a          372 c          384 g          338 t
ORIGIN      
        1 gtaaatatat tccgtacttg tattgacttt aagggcgtaa tcaccgataa ttaaatcatc
       61 gggaggcaat accgccaccc gctaaattgc cggtatcggc gcaaacagga gtcgtacatg
      121 aatactcaat tactgaaagt aggccagtgc ctgaagcacc tcaatgacga tgtagcagtt
      181 agtgaagtga ccctctcaga tggcgagatc tcttacaccc tcttaaacct cgaattaccg
      241 accgcgttca ccgttgagca agcccgtatc agcgcgcgct ttggctggac gcttacagat
      301 aagacgctat cccttgatga aatccgcagc cgccgcgaag tcgttcgcgt gtgtaagcag
      361 cgccgcgatg aagaagccgc gcggaaggca gaggaagaac agcgcagccg tgagcaggta
      421 tcaacgaatc cagagtatca ggatctactg accaaaaaag acgaacccag cacgacgaaa
      481 ctggcggcta aaaatatccg cctgctgctg aaaaagcatt tcaagggcat taagttttca
      541 gtgcgtatgc gtgattattc ctgcatcaat gtgggctgga cagacggccc gacgactgat
      601 gaagtggacg ccgtaatcag ccgttttcag gaaggccgtt ttgacggcat gacggatatg
      661 tatgaatacg gtaacgaccc attcaacaag gtttatgggg gcgtgcagta tcttttcact
      721 tcgcgcgaat gctcagatgc tctgatcgag gaagcgatcg ccagcgttaa aacccgctat
      781 aaatcggtag ttggggatga ttgcacggtc gcagctttcc gttccggcaa gctgtggaac
      841 gtaggtaatg aatattttag ccacggtctg caatcagcca ttcaccaggc agcggccgca
      901 atcagtaaaa aataaacagg atgcccccct aacggggggt aaaatgttat gaggttttag
      961 ctgtgtgtgg cagagttcta aaaagggaaa cgtgagagaa tatgaatacg attagtataa
     1021 cggaaatcgt gttgagtgtg cttcttgcag gcgctttggg accggttttg ttacgtcgaa
     1081 aaaaaggtct gctgttactg ttgttgattc tggtctgtac gatacttttg tttcatggtg
     1141 tcactacgat ttactgatgt ggtcgaaaat ctttaaaagc ggaaccccgg acgtcacccc
     1201 tccggggccg ttctgctgtg ctgcgcatcg agccgctacg cgtctcgccc cgctcacgcg
     1261 ggcagctgcc actgacgcct ccggcctgcg gcctccgcgc tccgcttagc aaccccttcc
     1321 cccagctgcc gctcatttcc ccttcagcct cctatcctga ttcgtccctt gcattatccg
     1381 tggattgtgc agctcagcgg ggcgctggcc gtgacggtgc ggtgtccccc gtaaccggcc
     1441 gcg
//
LOCUS       DAPOXO010000239         1431 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.243, whole genome shotgun sequence.
ACCESSION   DAPOXO010000239 DAPOXO010000000
VERSION     DAPOXO010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1431
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.243"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            59..>1431
                     /locus_tag="ROH59_005165"
     CDS             59..>1431
                     /locus_tag="ROH59_005165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001773871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter beta-barrel
                     domain-containing protein"
                     /protein_id="HDX4807516.1"
                     /translation="MTTVNKKLKKTASGAITWSVIVTQILSPVSLSLIPANSFASSGN
                     KDVTQIYASDEHANKVASFAASAGQSLANNNASSFAVNTLSTQATKEVVDWLQQYGNA
                     RIKLNVDDSFSLKDSSFDFLYPWLDTQDYVLFSQTSLHRTDDRNQTNIGLGIRHFTPD
                     NAMLGANVFYDYDLSRSHSRAGFGVEYWRDYFRLGVNTYFGLSDWKNSRDIDDYLERP
                     ANGWDFSAEGWLPAYPQLGASIQFEKYYGKNVGLFGSDNLQENPYAVTGGISYTPVPL
                     IKFSAQHKQGQSNTHDTTFGVEFNYRPGVSLAEQLSSDNVAVMREVQNRRYDFVERNN
                     NIVLEYKKKHALKISLPESVQGEGESIIPVTLTINNASGGIKSVQWNDSAFTAAGGKI
                     SGNGTSWQITLPAYKSEGVNSWNVGATVQDNRGNVSNYAVMNISVTDSGVSTADSSFT
                     LDGDSSPT"
BASE COUNT          399 a          269 c          335 g          428 t
ORIGIN      
        1 tcgcgcctct tgtcatacca gttatttttt tcattatatt cataacgttg attgaactat
       61 gaccactgtg aataaaaagt taaaaaaaac tgcatctggc gcgattacat ggtcggtaat
      121 tgttacccag atattatctc cagtttctct ttctttgatc ccagcaaaca gttttgcatc
      181 atctggtaat aaagatgtta cgcaaattta tgccagcgat gagcatgcaa ataaagtggc
      241 ctcatttgca gcaagtgcag gtcagagcct ggcgaataat aatgcaagta gttttgctgt
      301 aaatacttta tcaactcagg cgacaaaaga ggtcgtcgac tggttgcaac aatatggcaa
      361 tgcgcgcatc aagcttaatg tcgatgattc tttttccttg aaggattcat cattcgactt
      421 tttatatcca tggctggata ctcaggatta tgtgttattc agtcagacat cactacatcg
      481 tactgatgac cgaaatcaga ccaatattgg tttggggatt cgtcatttca ctcctgataa
      541 cgcaatgttg ggtgcgaatg ttttctatga ttacgattta agtcgtagtc actctcgtgc
      601 aggttttggg gttgagtact ggagggatta tttcaggctt ggtgtaaata cctattttgg
      661 tctatctgac tggaagaaca gtcgtgatat tgatgattat ctggaaagac ctgcaaatgg
      721 ctgggatttt tctgctgaag gatggctacc tgcttatccg caattagggg catctattca
      781 gtttgaaaaa tattatggta aaaatgtcgg gttatttgga agcgataacc tgcaggaaaa
      841 cccttacgca gttactgggg gaatttctta tacaccagtt cctctgatta agttttctgc
      901 acagcataag caaggacaga gcaacactca cgatacaacc tttggtgttg agtttaatta
      961 tcgcccgggc gtttccttgg ctgaacagct tagcagcgat aatgttgcag ttatgcgaga
     1021 agtccagaac cggcgttatg attttgttga acgaaataac aacattgttc tggagtacaa
     1081 gaagaagcat gcactgaaaa tcagtttgcc agagtctgtt cagggggagg gggaatcaat
     1141 catccctgta acactgacaa tcaacaatgc tagtggtggt atcaagtctg tacagtggaa
     1201 tgatagtgca ttcactgcgg ctggcggcaa gatcagtgga aatggcacat catggcagat
     1261 cactttaccg gcttataaaa gcgaaggtgt aaattcgtgg aatgttggag ccacagtaca
     1321 ggataacaga ggcaacgttt ccaactatgc cgtgatgaat attagcgtta ctgatagtgg
     1381 tgtctcgacg gctgattcgt cttttacact ggatggagat tcgtcgccga c
//
LOCUS       DAPOXO010000240         1361 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.244, whole genome shotgun sequence.
ACCESSION   DAPOXO010000240 DAPOXO010000000
VERSION     DAPOXO010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.244"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>1361
                     /locus_tag="ROH59_005166"
     CDS             <1..>1361
                     /locus_tag="ROH59_005166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011478180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntS/YbdA MFS transporter"
                     /protein_id="HDX4807517.1"
                     /translation="IDITGDSATVDNKGGMTVTDPDSIGILIDGDKAIVNNDGDNAIS
                     NGGTGTQINGDEATVNNNGNTTVDGQGSTGTEIAGNNVVVNQDGTLDVSGGGHGIDIT
                     GDSATVDNKGGMTVTDPDSIGILIDGDKAIVNNDGDNAISNGGTGTQVNGDEATVNNN
                     GNTTVDGQGSTGTEIAGNNAVVNQDGTLDVSGGGHGIDITGDSATVDNKGGMTVTDPD
                     SIGILIDGDKAIVNNDGDNAISNGGTGTQVNGDEATVNNNGKTTVDGQGSTGTEIAGN
                     NAVVNQDGTLDVSGGGHGIDITGDSATVDNKGGMTVTDPDSIGILIDGDKAIVNNDGD
                     NAISNGGTGTQINGDDATANNNGKTIVDGKDSTGTEIAGNNAVVNQDGTLDVSGGGHG
                     IDITGDSATVDNAISNGGTGTQVNGDEATVNNNGKTTVDGQGSTGTEIAGNNAVVNQD
                     GTL"
BASE COUNT          371 a          363 c          414 g          213 t
ORIGIN      
        1 attgatatca ccggcgacag cgccacggtg gacaacaagg gcggtatgac ggttaccgat
       61 ccggattcca ttggtattct gatcgacggt gataaagcca tcgtcaacaa cgacggcgac
      121 aatgccatca gcaacggcgg caccggcacg cagattaatg gcgatgaagc cactgtaaac
      181 aataacggta acaccaccgt tgatggtcag ggctctacag gtaccgaaat cgcgggtaac
      241 aacgtggtgg tgaatcagga cggtacgctg gatgtcagcg gcggcggtca cggtattgat
      301 atcaccggcg acagcgccac ggtggacaac aagggcggta tgacggttac cgatccggat
      361 tccatcggta ttctgatcga cggcgacaaa gccatcgtca acaatgacgg cgataacgcc
      421 atcagcaacg gcggcaccgg cacgcaggtt aacggtgatg aagccactgt aaacaataac
      481 ggcaacacca ccgttgatgg tcagggctcg accggtaccg aaatcgcggg taataacgct
      541 gtagtgaatc aggacggcac gctggatgtc agcggcggcg gtcacgggat tgatatcacc
      601 ggcgacagcg ccacggtgga taacaaaggc ggtatgacgg ttaccgatcc ggactccatc
      661 ggtattctga tcgacggcga caaagccatc gtcaacaacg acggcgacaa cgccatcagc
      721 aacggcggca ccggcacgca ggttaacggt gatgaagcca ccgtgaacaa taacggtaaa
      781 accaccgttg atggtcaggg ctcgaccggc acggaaatcg cgggtaataa cgctgtagtg
      841 aatcaggacg gcacgctgga cgtcagcggc ggcggtcacg ggattgatat caccggcgac
      901 agcgccacgg tggacaacaa gggcggtatg acggttaccg atccggattc catcggtatt
      961 ctgatcgacg gtgataaagc catcgtcaac aatgacggcg acaacgccat cagcaacggc
     1021 ggcaccggca cacaaattaa cggtgacgat gcgaccgcga acaacaacgg caaaaccatt
     1081 gtcgacggca aagattccac cggcacggaa atcgcgggta ataacgctgt agtgaatcag
     1141 gacggtacgc tggacgtcag cggcggcggt cacggtattg atatcaccgg cgacagcgcc
     1201 acggtggaca acgccatcag taacggcggc accggcacgc aggttaacgg tgatgaagcc
     1261 accgtaaaca ataacggtaa aaccaccgtt gatggtcagg gctcgaccgg cacggaaatc
     1321 gcgggtaaca acgcggtggt gaatcaggac ggtacgctgg a
//
LOCUS       DAPOXO010000241         1313 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.245, whole genome shotgun sequence.
ACCESSION   DAPOXO010000241 DAPOXO010000000
VERSION     DAPOXO010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.245"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>1313
                     /locus_tag="ROH59_005167"
     CDS             <1..>1313
                     /locus_tag="ROH59_005167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HDX4807518.1"
                     /translation="KHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLMQAI
                     AAEGDVVVSGATEPEWYYVIVLAGQSNAMAYGEGLPLPDSYDAPHPRIKQLARRNTVT
                     PGGEVCVFNDIIPADHCLHDVQDMSTINHPRADLSKGQYGCVGQGLHIAKKLLPYIPN
                     NAGILLVPCCRGGSAFTQGTEGTFSESTGASQDSARWGVGKPLYQDLLFRTKAALQKN
                     PKNVLLAICWMQGEFDMTNASYAQQPAAFLAMVQQFRADLAGLAAQCHGGSPASVPWI
                     CGDTTYAWKQEHGTQYEVVYGAYKGKESQQIYFVPFMTDGSGVNTPTNNPSEDPDIAG
                     SGYYGSASRTNKNWVSSNRPTHFSSWARRGIIPDRMATAILNVAGRTLAFISGKAPEI
                     KPSPGGDTPSGPSEDASVRTISLLPTAGDAAAQGWSIKNGGIQLS"
BASE COUNT          313 a          331 c          373 g          296 t
ORIGIN      
        1 aaacactatg atgttgtcag ggcggcgtcg ccgtcagatc ttgcggaaaa gctgacacat
       61 aaactgaaag agggctggca gccgtttggt agtccggtgg ccataacccc ttataccctg
      121 atgcaggcga ttgcagcaga aggtgatgtg gtcgtcagtg gtgcaactga gccggagtgg
      181 tactacgtca tcgtactggc cgggcaatcc aatgccatgg cttacggtga agggcttccg
      241 cttccggatt catacgatgc gccccatccg cgcattaagc aactggcccg tcgtaacaca
      301 gtgactcccg gtggtgaagt atgcgtattt aacgacatca ttcctgctga ccattgtctg
      361 catgatgttc aggatatgag tacgattaac catccccggg ctgacctgag caaagggcag
      421 tacggctgtg tcggacaggg cttacatatt gctaaaaaac tgcttccgta tatccctaat
      481 aatgcgggga tcctgctggt accatgctgt cgtggtggtt cggcattcac ccagggcacg
      541 gaggggacat tcagcgagtc cacgggggcc agtcaggatt cggctcgctg gggagtgggt
      601 aagccgttat atcaggatct gcttttccgc acgaaggcag cattgcagaa aaacccgaaa
      661 aacgttttgc tggcgatatg ctggatgcag ggggaattcg atatgacgaa tgccagttac
      721 gcccagcagc cagcagcatt tcttgcaatg gtacagcagt tccgtgctga ccttgccggg
      781 ctggcggcgc agtgtcacgg tggaagtccg gcatcagtcc cctggatttg tggcgacacg
      841 acatacgcgt ggaaacaaga acacggtacg caatatgaag tggtatatgg tgcatataaa
      901 ggtaaagaat cccagcagat ttattttgtt ccctttatga ccgatggtag cggagttaat
      961 acaccgacaa acaacccgtc agaagatcct gatattgccg ggtctggtta ttacggttcg
     1021 gcatcccgaa cgaacaaaaa ctgggtatca tcaaatcgcc cgacgcattt cagctcatgg
     1081 gcgcgtcgtg gcattattcc cgatcgtatg gcaactgcta ttctgaacgt agccggtcgc
     1141 accttagcct tcattagtgg taaggcaccg gaaatcaaac cctcgcccgg cggcgacacg
     1201 ccatcggggc cgtctgaaga tgcatccgta cgcacaatct ccctgttgcc gacagccgga
     1261 gatgctgctg cgcagggctg gagcattaag aatggcggaa ttcagttgtc aga
//
LOCUS       DAPOXO010000242         1300 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.246, whole genome shotgun sequence.
ACCESSION   DAPOXO010000242 DAPOXO010000000
VERSION     DAPOXO010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.246"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT          420 a          249 c          223 g          408 t
ORIGIN      
        1 cactagctgt gctgggttag caataatcca acatttttat cctgattatg tttataaaag
       61 cgaacgtttg cttaataact aacgtaagtg gaccagttct tctgagtgaa cttaaatgga
      121 gtagcgatag ttacttataa taactttgcc atacaaacgc catgctcttg catgctatgt
      181 acctttatat atttatcaat cggatacgaa tctaataata accctcatca ttaatgcaac
      241 taatcttatc tatatatcat gtgatatgtt ctgtaacaag taaaatcaac ataaaaaatt
      301 cagcaaaatt taatattcgt tcaactagcc gtctcacata tgacattatt agtcaactcc
      361 atttaccaca aaatggctat ttcatggaac gcagtaattt cttagtggct attatcaagc
      421 taattcttag gtccctagcg attattcctg gctggttcgt cagtttaggt catgagattg
      481 ttacattcct ttttatcctg gagatatggg ggaacgcagg cgacgctttt tcatctacat
      541 ccgttggtaa atatggcttt ggtcactacg acttaaaccc tcctcaatca cagctactcg
      601 ccgggcgata tggcaaacaa actaattgaa acatcatcct gaaaacacca gcatcaacaa
      661 gcctctccag atcgacatca ggagtgacca gttacaagcc acaaaccaag aaacatattt
      721 catgatgaga attatgctca gcctgatggc gggtaaacac ttattttcac caagctcact
      781 gagttagctt gcaaagcttt ctttgtttat attctaaata aattatttat aaaacatata
      841 gttaaaagaa aatctttagt ttttgaagac caccgcaagt gttcgtctgg cttcacatgg
      901 catctgcctc ttagaaaaag atcgacatat tttgtgacac gaattgcaaa tctggttttg
      961 ttgtatggat tgcgtgattt ttgatctggt ataacaggta taaaggtgca ccacgatagt
     1021 caatgaaact gggcatctcg caatctatgg caaacatcac ttcagttctt tctcatcggg
     1081 tgatgaaaac gcacttcagt ctgaaaggaa tatgaaaatg agatcaacag acactctatt
     1141 ttatgactct gggtaaaatg gattgagtaa gcgatatagc ttacgaaaat tcaaatcaat
     1201 taaacatcag cagagatttt atactcaggt atttaatctg gctctctgtt tatttaaata
     1261 atgtggaaag agatttttca caggagacat tatacaaaaa
//
LOCUS       DAPOXO010000243         1299 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.247, whole genome shotgun sequence.
ACCESSION   DAPOXO010000243 DAPOXO010000000
VERSION     DAPOXO010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1299
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.247"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            35..1147
                     /locus_tag="ROH59_005168"
     CDS             35..1147
                     /locus_tag="ROH59_005168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HDX4807519.1"
                     /translation="MAQNHEVVAFDTHQKKVDLLNDKLSPIEDKEIENYLSTKILNFR
                     ATTNKYEAYKNANYVIIATPTNYDPGSNYFDTSSVEAVIRDVTEINPNAIMVVKSTVP
                     VGFTKTIKEHLGINNIIFSPEFLREGRALYDNLHPSRIIIGECSERAERLAVLFQEGA
                     IKQNIPVLFTDSTEAEAIKLFSNTYLAMRVAFFNELDSYAESFGLNTRQIIDGVCLDP
                     RIGNYYNNPSFGYGGYCLPKDTKQLLANYQSVPNKLISAIVDANRTRKDFITNVILKH
                     RPQVVGVYRLIMKSGSDNFRDSSILGIIKRIKKKGVKVIIYEPLISGDTFFNSPLERE
                     LAIFKGKADIIITNRMSEELNDVVDKVYSRDLFKCD"
BASE COUNT          412 a          208 c          245 g          434 t
ORIGIN      
        1 cgctggttac gttgggcttt caaatggaat tctaatggct caaaatcatg aagtggttgc
       61 atttgatacc catcaaaaaa aagttgactt acttaatgat aaactctctc ctatagagga
      121 taaggaaatt gaaaattatc tttcaactaa aatacttaat tttcgcgcaa ctactaacaa
      181 atatgaagcc tataaaaatg ccaattacgt tattattgct acaccaacga attatgaccc
      241 aggttcaaat tactttgata catcaagcgt tgaagctgtc attcgtgacg taacggaaat
      301 caacccaaac gcaattatgg tggttaaatc tacggtccca gtaggtttca caaaaacaat
      361 taaagaacat ttaggtatta ataatattat cttctctcca gaatttttac gagaaggaag
      421 agccctatac gataatctcc atccatctcg cattattatc ggtgaatgtt ctgaacgggc
      481 agaacgtttg gcagtgttat ttcaggaagg agcgattaaa caaaatatac ccgttttatt
      541 tacagattct acggaagcgg aagcgattaa gttattttca aatacttatt tggctatgcg
      601 agttgcattt tttaatgaat tggatagtta cgcagaaagt tttggtctga atacgcgtca
      661 gattattgac ggtgtttgtt tggatccgcg cattggtaat tactacaata atccttcttt
      721 tggttatggt ggctactgtt tgccaaaaga taccaagcaa ttattagcca actatcagtc
      781 tgttccgaat aaacttatat ctgcaattgt tgatgctaac cgtacacgta aggactttat
      841 cactaatgtt attttgaaac atagaccaca agttgtgggg gtttatcgtt tgattatgaa
      901 aagtggttca gataatttta gagattcttc tattcttggt attataaagc gtatcaagaa
      961 aaaaggcgtg aaagtaatta tttatgagcc gcttatttct ggagatacat tctttaactc
     1021 acctttggaa cgggagctgg cgatctttaa agggaaagct gatattatta tcactaaccg
     1081 aatgtcagag gagttgaacg atgtggtcga caaagtctat agtcgcgatt tgtttaaatg
     1141 tgactaatgt attgttatat actattaact attaagagaa ggaaatgcat tatttaatcc
     1201 gttaaaaata tgcctcgttg gtatgttctt tattaatcct cgatcgtaaa ataagatgtt
     1261 ggttaaattt cttgccctgc tgttgtgttt atatcgaat
//
LOCUS       DAPOXO010000244         1278 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.248, whole genome shotgun sequence.
ACCESSION   DAPOXO010000244 DAPOXO010000000
VERSION     DAPOXO010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.248"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1205
                     /locus_tag="ROH59_005169"
     CDS             <1..1205
                     /locus_tag="ROH59_005169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDX4807520.1"
                     /translation="VAFIFMQLYFIYDRRQFSNCILSLAFLSCLIYFVKTVIIIQQII
                     EGRLTSSVVQNDIAIYYLFRQMSLCMLIFLALINKVSENTKQRNLFSKKVTLCISLFF
                     VLGGPIVAHIFSSHYESYDLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNG
                     LRCDIWNGVSVIAFCAVLYNISLLFMSRYSVSIWYISRTIEVVSKLTVLVIFMCHIFS
                     ALRVTKDIAHRDPLTNIFNRNYFFNELTVQSASAKKTPYCVMIMDIDHFKKVNDTWGH
                     PVGDQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTEIDTECAKALAERIRENVERL
                     TGDNPEYAIPQKVTISIGAVVTQKNELNPKEIYQLADNALYEAKETGRNKVVVKEAEI
                     LINRKDDE"
BASE COUNT          369 a          220 c          284 g          405 t
ORIGIN      
        1 ctgttgcatt tatttttatg cagttgtatt tcatttatga ccgtaggcaa ttttcaaact
       61 gtatacttag tttggctttt ctaagttgtt tgatttactt tgttaaaacc gtcattatca
      121 ttcagcaaat tattgagggg cgtttgacaa gcagtgttgt tcaaaatgac attgcaattt
      181 attatttgtt tcgtcagatg agtttgtgca tgttaatatt tctggcattg ataaataaag
      241 ttagtgaaaa cacaaaacag cgcaatttat tttccaaaaa agtgactttg tgcataagtt
      301 tgttttttgt tcttgggggg ccgatagttg ctcacatatt ttctagccat tatgagagct
      361 acgatttaca cattgccgag ttaaccaatg aaaatggtca ggtggtttgg aaagcctcat
      421 atgttaccat aatgattttc atgtggttaa ccttgctttc ggttaatcta tactttaatg
      481 gtttacgctg tgatatctgg aacggggtgt cggtgattgc tttttgtgcc gtgctgtaca
      541 atatctctct gttatttatg agcaggtata gcgtgtccat ttggtatatt agtcgcacta
      601 ttgaagtagt cagtaagtta accgttttgg taatttttat gtgccatata ttcagtgcgc
      661 tacgagtaac aaaggacatt gcacatcgcg atcccttaac caatatattc aacagaaatt
      721 atttttttaa tgaactgacg gttcaatcag catcggccaa aaaaacacct tattgcgtca
      781 tgattatgga tattgaccac ttcaaaaaag tcaacgacac ctggggacat ccggttggcg
      841 atcaagtgat aaagacagtg gtgaatatca ttgggaaaag catacgacca gatgaccttt
      901 tagcgcgcgt tggcggcgaa gagtttggcg tcttgctgac ggagatcgat actgaatgtg
      961 cgaaagcttt agcggaaagg attcgggaaa atgttgaacg tttaactggc gataatcctg
     1021 aatacgccat accacaaaaa gtgacgatta gtattggcgc tgttgtaacg cagaaaaatg
     1081 agttaaaccc taaggagatc tatcaactgg ctgataacgc actttacgag gcgaaagaga
     1141 ccgggcgtaa taaggtggta gtaaaagagg cagaaattct tatcaaccgc aaggatgatg
     1201 aatgagtctg tcgctagttg tcaacctccg cctggggctt ctcatccccc cggtgtatgc
     1261 aatatacgaa aaaaaagc
//
LOCUS       DAPOXO010000245         1269 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.249, whole genome shotgun sequence.
ACCESSION   DAPOXO010000245 DAPOXO010000000
VERSION     DAPOXO010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1269
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.249"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..1269
                     /locus_tag="ROH59_005170"
     rRNA            <1..1269
                     /locus_tag="ROH59_005170"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          316 a          296 c          399 g          258 t
ORIGIN      
        1 taggcgacga tccctagctg gtctgagagg atgaccagcc acactggaac tgagacacgg
       61 tccagactcc tacgggaggc agcagtgggg aatattgcac aatgggcgca agcctgatgc
      121 agccatgccg cgtgtatgaa gaaggccttc gggttgtaaa gtactttcag cggggaggaa
      181 gggagtaaag ttaatacctt tgctcattga cgttacccgc agaagaagca ccggctaact
      241 ccgtgccagc agccgcggta atacggaggg tgcaagcgtt aatcggaatt actgggcgta
      301 aagcgcacgc aggcggtttg ttaagtcaga tgtgaaatcc ccgggctcaa cctgggaact
      361 gcatctgata ctggcaagct tgagtctcgt agaggggggt agaattccag gtgtagcggt
      421 gaaatgcgta gagatctgga ggaataccgg tggcgaaggc ggccccctgg acgaagactg
      481 acgctcaggt gcgaaagcgt ggggagcaaa caggattaga taccctggta gtccacgccg
      541 taaacgatgt cgacttggag gttgtgccct tgaggcgtgg cttccggagc taacgcgtta
      601 agtcgaccgc ctggggagta cggccgcaag gttaaaactc aaatgaattg acgggggccc
      661 gcacaagcgg tggagcatgt ggtttaattc gatgcaacgc gaagaacctt acctggtctt
      721 gacatccacg gaagttttca gagatgagaa tgtgccttcg ggaaccgtga gacaggtgct
      781 gcatggctgt cgtcagctcg tgttgtgaaa tgttgggtta agtcccgcaa cgagcgcaac
      841 ccttatcctt tgttgccagc ggtccggccg ggaactcaaa ggagactgcc agtgataaac
      901 tggaggaagg tggggatgac gtcaagtcat catggccctt acgaccaggg ctacacacgt
      961 gctacaatgg cgcatacaaa gagaagcgac ctcgcgagag caagcggacc tcataaagtg
     1021 cgtcgtagtc cggattggag tctgcaactc gactccatga agtcggaatc gctagtaatc
     1081 gtggatcaga atgccacggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc
     1141 atgggagtgg gttgcaaaag aagtaggtag cttaaccttc gggagggcgc ttaccacttt
     1201 gtgattcatg actggggtga agtcgtaaca aggtaaccgt aggggaacct gcggttggat
     1261 cacctcctt
//
LOCUS       DAPOXO010000246         1255 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.250, whole genome shotgun sequence.
ACCESSION   DAPOXO010000246 DAPOXO010000000
VERSION     DAPOXO010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.250"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            256..807
                     /gene="papX"
                     /locus_tag="ROH59_005171"
     CDS             256..807
                     /gene="papX"
                     /locus_tag="ROH59_005171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PapX"
                     /protein_id="HDX4807521.1"
                     /translation="MRACTQTVCFSNMENNEMNNTDTLEKIIRHQKNKDPAYPFREHL
                     LMQLCIRTNKRMQDNISEFLGVYGINHSAYMVLTTLFAAENHCLSPSEISQKLQFTRT
                     NITRITDFLEKAGYVKRTDSREDRRAKKISLTSEGMFFIQRLTLAQSMYLKEIWDYLT
                     HDEQELFEVINKKLLAHFSDASS"
BASE COUNT          415 a          235 c          262 g          343 t
ORIGIN      
        1 acaacgttta tcgacctcac acgaacaacg atggtttacc gccttgctta catgaagaaa
       61 agtggaaaca ggttattccg gtgtcctgat tttgtgaacc actacaataa tcctttttca
      121 cagacttgtc agcagccagc atttatgttc ttttacctgc gggaatttat ccgtctgcct
      181 gtcgggacta ctctgtcata cagaaatcag gtaggaataa attgtagtgg aaagtcgatg
      241 tttaccggat gactgatgcg cgcttgtaca cagacagtgt gtttcagtaa tatggagaat
      301 aatgaaatga ataacacaga cacattagaa aaaataatca gacaccaaaa aaacaaagac
      361 cccgcatatc cctttcggga acatttgttg atgcagctct gtattcgcac aaataaaaga
      421 atgcaggata atatatctga atttctgggg gtgtatggaa taaatcactc agcatatatg
      481 gttctcacca cattattcgc agcggagaac cattgtctgt caccttcaga gataagccag
      541 aaacttcagt ttaccagaac taatattacc cgcattacag attttttaga aaaagccgga
      601 tatgtaaaaa ggacggatag cagggaggat cgccgtgcta aaaaaatcag tctgacatct
      661 gaaggtatgt tttttattca gaggctcact cttgcacaaa gcatgtatct gaaagaaatc
      721 tgggattatc tgacccatga tgaacaggaa ctgtttgaag tcattaataa aaagttactg
      781 gcacattttt ctgatgccag ctcataaagt gcgaaatatc tgaggatgct ggatagcttc
      841 aggcaagaga ataatgattc ttgcagatgt gtttttccgg atacaaaaac aaaagtaaaa
      901 aattgcagcg ccaggccacc tttcaaagca gggaggcctg taccgcgtcg aaaatttcag
      961 ccagttaatg taattgtctg aaccaggcac ttcgcccggg caggagaagg agcgtggttg
     1021 cggtcatcct gtatactgaa gtcgttatga aggaataata caaataattg cccgttttct
     1081 ctgtacgata gaggcaggtg tgtatgattg cattactatg tttttgtgat ataaaaaact
     1141 aaatggtgag atatgcattt taaaatataa caaaaatcac catgaaataa gaataattat
     1201 ccacggagaa cataaactgc agactgttac aatgcatgct gttcatcttg acaat
//
LOCUS       DAPOXO010000247         1247 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.251, whole genome shotgun sequence.
ACCESSION   DAPOXO010000247 DAPOXO010000000
VERSION     DAPOXO010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.251"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(53..367)
                     /locus_tag="ROH59_005172"
     CDS             complement(53..367)
                     /locus_tag="ROH59_005172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807522.1"
                     /translation="MRGAAPAALPARLSGQKVVYGCMQGTGVIFRDTVTVSGCLLLRP
                     LRLPAAWRHPVVRPDSDRQLLAHPPVSAEPAGAVSGCRYGPMRENPACSDRSGRAAPV
                     AP"
     gene            complement(438..629)
                     /locus_tag="ROH59_005173"
     CDS             complement(438..629)
                     /locus_tag="ROH59_005173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807523.1"
                     /translation="MNISTETREILRNYKAVINARRREMGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(626..1048)
                     /locus_tag="ROH59_005174"
     CDS             complement(626..1048)
                     /locus_tag="ROH59_005174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDX4807524.1"
                     /translation="MYCTVKEIIREVLNTDVPDSECVFAVVLTRGDVRHIAQDWSLTD
                     DELETVMQRLDDAFAHGADVSIVHDVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGEHMS"
     gene            complement(1095..>1247)
                     /locus_tag="ROH59_005175"
     CDS             complement(1095..>1247)
                     /locus_tag="ROH59_005175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX4807525.1"
                     /translation="LTSLVINRQLWLYHDSGDAGLTQLYRMRDAQLWRHIEFHPECNA
                     IYAALD"
BASE COUNT          246 a          406 c          339 g          256 t
ORIGIN      
        1 cgccatcagg cgcagtttcc tcacacaccg tcaggtgtgc agggagcgca ggtcacggcg
       61 cgacaggggc ggcgcgaccg gaacggtcgc tgcaagccgg gttttcacgc atcggaccgt
      121 agcggcagcc cgaaaccgcg ccagcgggtt cggcggagac tggcgggtgc gccagcagct
      181 gcctgtcgga gtcgggcctg acgaccggat gccgccaggc agccgggagc cgaagtgggc
      241 gcaataaaag acagccagaa acggtgacag tgtcacggaa tatcacacct gttccctgca
      301 tacagccata cactaccttc tgaccggaaa gccgggccgg cagcgccgca ggcgctgcac
      361 cccgcatttc cggcaggcgt cagcctgcca ggggttttcg cgcgggctga caggcggcct
      421 ccaccgcctg ccctgtatca cctgtttctg ctgccctgta agatgtagtg accgcccagg
      481 aaaaccgcct gctgattcgc cacaaaatcg cagatttcat caacaatctg cgcagtggtg
      541 agcggtttct gccccatttc acgacgccgc gcattaatca cggctttgta attgcgcaga
      601 atttcgcggg tttctgtgct gatattcatg acatgtgctc cccgtccagc gcctgtaaca
      661 caacgtccat tgcttcgcgt tcttccctga cgaatgcgtc accgtcgccc ccgttctcgc
      721 tcccgacggc atacaggcgc ttcatttcac tgcctgccag cgccatcact ttttccagca
      781 tcaccgccgg aactgtcacc tgacggctgg cgcgcttttc ttccatcagc tcacgaacaa
      841 cgtcgtgaac aatgctgaca tccgcaccat gcgcaaaggc atcgtccagt cgctgcatga
      901 cggtttccag ctcatcgtct gtcagactcc agtcctgggc tatgtgacgc acatccccac
      961 gggtcagcac cacggcaaaa acgcattcac tgtccggcac gtctgtgttc agcacttcgc
     1021 ggataatttc tttaacagta cagtacatgt tctcgtctcc tttacagggg cggcattgcc
     1081 gccccgtccg ttaatcagtc cagtgccgcg taaatcgcgt tgcattcggg gtgaaattcg
     1141 atgtgacgcc acaactgcgc atcgcgcatc cggtaaagct gggtcagtcc tgcatccccg
     1201 ctgtcgtggt acagccacaa ctggcggtta atcacaaggg aagtcag
//
LOCUS       DAPOXO010000248         1235 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.252, whole genome shotgun sequence.
ACCESSION   DAPOXO010000248 DAPOXO010000000
VERSION     DAPOXO010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.252"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            120..647
                     /locus_tag="ROH59_005176"
     CDS             120..647
                     /locus_tag="ROH59_005176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDX4807526.1"
                     /translation="MSARGINKVILVGRLGNDPEVRYIPNGGAVANLQVATSESWRDK
                     QTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTVQMLGRAPQQNAQAQPKPQQNGQPQSADATKKGGAKTKGRGRKAAQPEPQPQ
                     PPEGEDYGFSDDIPF"
     gene            705..938
                     /locus_tag="ROH59_005177"
     CDS             705..938
                     /locus_tag="ROH59_005177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 domain-containing protein"
                     /protein_id="HDX4807527.1"
                     /translation="MSEYFRILQGLPDGSFTREQAEAVAAQYRNVFIEDDQGTHFRLV
                     VRQDGTLIWRSWNFEDCAGYWMNQYIRDFGILK"
     gene            997..>1235
                     /locus_tag="ROH59_005178"
     CDS             997..>1235
                     /locus_tag="ROH59_005178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDX4807528.1"
                     /translation="MPVTKCEPETTRKASRKYAKTQETVLSALLAQTEEVSVPLASLI
                     KSPLNVRTVPYSAESVSELAESIKGVGLLQNLVVHT"
BASE COUNT          295 a          315 c          393 g          232 t
ORIGIN      
        1 gcggggagaa acccctgtga agtggacggc aggaggagct ttcgctcctc tgaaggggca
       61 catgaacgtc ccgtcgccgg tatccggttt atctcacatc tttcagtcag gaggttctta
      121 tgagtgcacg tggtatcaac aaggtcatcc tcgtcgggcg tctgggtaat gatccggaag
      181 tccgttacat ccccaacggg ggcgcagtgg caaacctgca ggtggccaca tcagaaagct
      241 ggcgtgacaa acagacgggg gagatgcggg agcagacgga atggcaccgc gtggtgctgt
      301 tcggcaagct cgcggaagtg gcaggtgaat atctgcgcaa gggtgcgcag gtctacatcg
      361 aaggtcagct tcgcacccgt agctgggaag ataacggtat cacccgttac gtcactgaaa
      421 ttcttgttaa gaccacgggc accgtgcaga tgctgggacg tgcaccacag cagaacgctc
      481 aggcgcaacc gaagcctcag cagaatgggc agccacagag tgctgacgcg acgaaaaaag
      541 gtggcgcgaa aacgaaaggc cgtggacgta aggccgcgca gccagagcct cagccgcaac
      601 cgccggaggg ggaggattac gggttttcag acgacatccc gttctgatcg ggctgactgt
      661 gacaaccgcc ccgccctgtg cggggcatca ccggagatat gaggatgagc gaatatttca
      721 gaatacttca gggactgccg gacggctcct ttacccgcga acaggcggaa gccgttgccg
      781 cacagtaccg gaacgtcttt atcgaggatg atcagggaac gcattttcgc ctggttgtcc
      841 gtcaggatgg cacgttgatc tggcgctcct ggaattttga ggactgtgcc gggtactgga
      901 tgaaccagta catcagggat ttcgggattc ttaagtaaga gaggtgccgg acgcgcgaac
      961 gtccggcagg acataagcaa ttataagggg atgattatgc ctgtaacgaa gtgtgaacca
     1021 gaaaccaccc gcaaagcaag ccgtaaatat gcaaaaacgc aggaaacagt cctgtctgcc
     1081 ctgctggcgc agacggagga agtgagcgtg ccgctggcct cgctgattaa atcaccgctg
     1141 aatgtgcgca cggtgccgta ttctgcggag tccgtcagcg aactggcgga gtccattaag
     1201 ggcgttggcc tgttgcagaa tctggtcgtg catac
//
LOCUS       DAPOXO010000249         1233 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.253, whole genome shotgun sequence.
ACCESSION   DAPOXO010000249 DAPOXO010000000
VERSION     DAPOXO010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1233
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.253"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..606)
                     /locus_tag="ROH59_005179"
     CDS             complement(<1..606)
                     /locus_tag="ROH59_005179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysogenic protein"
                     /protein_id="HDX4807529.1"
                     /translation="MGTALISSFISGAIAIISIAISTYNQNRINKLNESLDVRRKHQY
                     YIEPLIRSASDLQSRIYNILELGFIEEFYHNGNKRQQDYVINNTVFLFSQFFAWTEAA
                     RIDIQYLSLEKNKKMREFIRLQNNINSLIQTDVFGQYFMFFIGEQRAIAEKMLISTDT
                     GFDCIGYGSFTKENCFINEPFFLDLNNEVINMTRDIGIYKER"
BASE COUNT          398 a          238 c          158 g          439 t
ORIGIN      
        1 cctttcttta taaattccga tatctcttgt catatttatc acttcattgt ttaaatctaa
       61 aaaaaatggc tcattgataa agcaattttc ctttgtgaaa ctgccgtaac ctatgcaatc
      121 aaatccagta tctgttgata tcagcatctt ttctgcaata gctctctgct ctcctatgaa
      181 aaacataaaa tactgaccaa agacgtctgt ttggattaat gagttaatat tgttctgtaa
      241 tctaataaac tccctcattt ttttattttt ttctaggcta aggtattgaa tgtctatgcg
      301 ggcagcttct gtccatgcaa aaaactggga aaaaagaaaa acagtattgt tgataacata
      361 atcttgttgg cgcttattcc cattatgata aaactcttca atgaacccca attctaatat
      421 attataaata cggctttgta agtctgaagc tgagcgaatt aacggttcaa tatagtactg
      481 atgttttctc cttacatcca gtgattcatt gagcttgttt attctattct gattataagt
      541 agatatagca atagagatta tagctattgc accactaata aagcttgaaa ttaatgccgt
      601 acccatctaa aagtcctttg attcttgctt ggttaacaaa atgacataat tttatttaat
      661 gccataacaa cttaacaata tatcataata tgattattat ggtgtagctt gtcgcatcta
      721 cgctccatta caaacagatg taagatataa cctatatgtt ttagccagca aattcgaaag
      781 cattcaaagt agtctcatcg aactctcgaa accctatgtc ttcgggtata aaatatttaa
      841 atccatttgc ataatatcga ctcatgttta ttatattctc cccattcacc attaagattt
      901 gacattattt tcaacaatcg gttattgcaa gattgaaata tatttttact tgacacaata
      961 ttccatgtag cccagcgatt cgacttaccc ccaactatac ggacaatcta aattaaatcg
     1021 atgatttttt gatacattct cctctctcca ttactttatg tttttgttcc ccaaaaatac
     1081 cttgctctct aaaaaataat tgttctttaa gttcaaaatc gagatctaca tgagcgttag
     1141 atacaaagct aatatgttga aatgtctttc ccccccccat aacggcattg ttatctaaac
     1201 tatgttacac aaatataata ttaccctttc aac
//
LOCUS       DAPOXO010000250         1215 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.254, whole genome shotgun sequence.
ACCESSION   DAPOXO010000250 DAPOXO010000000
VERSION     DAPOXO010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.254"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            208..858
                     /gene="zinT"
                     /locus_tag="ROH59_005180"
     CDS             208..858
                     /gene="zinT"
                     /locus_tag="ROH59_005180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HDX4807530.1"
                     /translation="MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGV
                     FDDTNVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYRKGYA
                     TDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
                     YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH"
BASE COUNT          398 a          235 c          221 g          361 t
ORIGIN      
        1 cgccctatcc ggcccacaca gatcgcatca agttatgttt cgtttgtcat caacctttca
       61 tcaccagaat aatttatttt atttcaataa gatagttaaa tacacctgag aataccatgc
      121 tctcatttcc taatgagttg ttgcattttt tcatatgtta caatataaca ttacacatca
      181 tgtacattaa ctctggagga aattgttttg gcgattcgtc ttcataaact ggctgttgct
      241 ttaggtgtct ttattgttag cgctcctgcc ttttcgcatg gtcatcactc acacggcaaa
      301 cccttaacag aggtcgaaca aaaagctgct aatggtgttt ttgatgatac caatgtacaa
      361 aaccgaacgc tcagtgactg ggatggagtc tggcaatccg tttacccttt actgcaaagt
      421 ggcaaacttg accccgtctt tcagaagaaa gcggatgcag ataaaaccaa aacatttgct
      481 gaaattaaag attattatcg caaaggttat gcgacagata tcgaaatgat tggcattgag
      541 gacggcattg tcgaattcca tagaaataat gaaacaacat cctgtaaata tgattacgat
      601 ggatacaaaa tactcaccta taaatcaggc aagaaaggcg ttcgttactt attcgaatgt
      661 aaagatcctg aaagcaaagc ccctaaatat atacaattta gcgatcatat aattgcacca
      721 cgaaaatcat ctcattttca catttttatg ggtaatgatt cccagcaatc tttattgaat
      781 gaaatggaaa actggccaac gtattatccc tatcagttga gtagcgaaga agtggtcgag
      841 gagatgatgt ctcattgatt tttttgcgct gacttcagtt atttaacaga acagtgcctg
      901 gtagtaacaa caataattta ccaagacaaa taagtaagac aaactcagac acgctcatac
      961 ttgagtcgtg tcttttttat tatgtctgta gaaaaaaact gagaaaaagg cgaacaataa
     1021 atacacaact cagccataca gactggcagc gcaaatgtct ccaggagcaa gtcatctgtc
     1081 atggtaaagc taaccagaaa tataggttaa ttttggtgtt taaacctttt ttacttgtta
     1141 gtatgataca aaggctttca aaaaagctgg gaaattcaac aactcttgga aattatggac
     1201 tttgtcccgc ggctt
//
LOCUS       DAPOXO010000251         1214 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.255, whole genome shotgun sequence.
ACCESSION   DAPOXO010000251 DAPOXO010000000
VERSION     DAPOXO010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.255"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(10..1161)
                     /locus_tag="ROH59_005181"
     CDS             complement(10..1161)
                     /locus_tag="ROH59_005181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS30 family transposase"
                     /protein_id="HDX4807531.1"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDT
                     GGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRR
                     YYKAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQK
                     TLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPI
                     HERSRNIDNRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQALT
                     DKFLSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIR
                     QYFPKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
BASE COUNT          269 a          285 c          268 g          392 t
ORIGIN      
        1 gttgtagatt caatctgtca atgcaacacc cctttcaatt atctctttcg gtgttttgaa
       61 cttcagtgtc tttctcggtc tgttgtttag ctgagcagca accagatcta gttcatgttg
      121 agtatattgg gcaagacatg tctttttagg aaagtactgc cgaattagcc catttgtgtt
      181 ctcatttgtt ccccgctgcc aaggactctg aggatcgcag aagtaaactt taacgccggt
      241 gctgacagta aattctagat gtctggccag ttccattcct ctgtcccatg tcagtgattt
      301 tctgagttct gacggtaaac tcaggaattt gtcggtaaga gcctgattta ctgagacaga
      361 atctttgccc ctgagtctaa ggatgatcgt ataacgtgat tttcggtcta caagtgtggc
      421 tatatgagag ttttttgtac ctgagactaa atcgccctcc caatgtccca gagagcgtct
      481 gttatcgata tttcgggaac gttcgtgaat tggtgttccg ttcactatgt taatcgtacc
      541 tctttcgcct ttgcgggtat gacgcctgcc atggcgaagg ctatgcgacc gtcgcagatg
      601 ctgtatattc aggtggtgta gcgcttcacg gctacgaaag tacagcgttt tataaattgt
      661 ctcaggtgat attcgcagcg ttttttgacg tggttttgtt cgccttaacc atcctgatat
      721 ttgctctgga gaccatttca tctccagctt ttccagaaca agctttcgca atggtaaatt
      781 ttgatccagt aagcacggtt ttggcctttt cgccattctg ttggctcggt tattagcatc
      841 aacagctttg taatagcgtc tgccccgatt acgctgaact tcacgtgaga tcgtcgaagg
      901 actgcgattc agcgcagtag ctatcgcacg aatgctcatt ttggctgaca aaccagctcg
      961 tatctcctcg cgctcagaca gtgtcaggtg agctacagcc cgcttacgct catggggttt
     1021 tatgccgcca gtatccctta acatagtgaa gatcgttccg ggttttgaac ccaggatatt
     1081 cgctatttca ctgaagcctg ttccgttctt ccatagttca aaaacagagg ctttttcctc
     1141 tgctgtaaat gttcgtctca ttcaaaaaac ctccgcaacc ccatgttttc acataactgt
     1201 tgcgttgacc aatt
//
LOCUS       DAPOXO010000252         1135 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.256, whole genome shotgun sequence.
ACCESSION   DAPOXO010000252 DAPOXO010000000
VERSION     DAPOXO010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.256"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            21..548
                     /locus_tag="ROH59_005182"
     CDS             21..548
                     /locus_tag="ROH59_005182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDX4807532.1"
                     /translation="MAVRGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSETWRDK
                     QTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTMQMLGSAPQQNAQVQPQPQQNGQPQSADATKKGSAKTKGRGRKAAQPEPQPQ
                     PPEGEDYWFSDDIPF"
     gene            605..838
                     /locus_tag="ROH59_005183"
     CDS             605..838
                     /locus_tag="ROH59_005183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 domain-containing protein"
                     /protein_id="HDX4807533.1"
                     /translation="MSEYFRILQGLPDGSFTREQAEAVAAQYRNVFIEDDQGTHFRLV
                     VRNNSGLVWRTWNFEDGAGYWMNHVIRNFGILK"
     gene            897..>1135
                     /locus_tag="ROH59_005184"
     CDS             897..>1135
                     /locus_tag="ROH59_005184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDX4807534.1"
                     /translation="MPVTKCEPETTRKASRKYAKTQETVLSALLAQTEEVSVPLASLI
                     KSPLNVRTVPYSAESVSELAESIKGVGLLQNLVVHT"
BASE COUNT          294 a          285 c          346 g          210 t
ORIGIN      
        1 tcaacagaag gagacacatc atggcagttc gtggaattaa caaggtcatt cttgtcggtc
       61 gtctgggaaa agatccggaa gtccgttaca tccccaacgg gggcgcagtg gcaaacctgc
      121 aggtcgccac gtcagaaacc tggcgcgaca aacagacggg ggaaatgaag gaacagacgg
      181 aatggcaccg cgtggtgctg ttcggcaagc tcgcggaagt ggcaggtgaa tatctgcgta
      241 agggcgcgca ggtctacatc gaggggcaac tccgtacccg tagctgggaa gataacggta
      301 ttacccgtta cgtcactgaa atccttgtga aaaccacggg caccatgcag atgctgggga
      361 gtgcaccaca gcagaacgct caggtgcaac cgcagcctca gcagaacggc cagccacaga
      421 gtgctgacgc aacgaaaaaa gggagcgcga aaacgaaagg ccgtggacgt aaggctgcgc
      481 agccggagcc tcagccgcaa ccgccggagg gtgaggatta ctggttttca gacgatatcc
      541 cgttctgaat gactgactgt gaaaaccgcc ccgtccagtg cggggcatca ccggagagat
      601 gaggatgagc gaatatttca gaatacttca ggggctgcct gacggctcct ttacccgcga
      661 acaggctgaa gccgttgccg cacagtaccg gaatgtcttt atcgaggatg atcagggaac
      721 gcattttcgc ctggttgtcc gcaataacag tggcctggtc tggcgcacct ggaattttga
      781 ggacggtgcc gggtactgga tgaaccatgt catccggaat ttcggcattc ttaagtaaga
      841 gaggtgccgg acgcgcaaac gtccggcagg acataagcaa ttataagggg atgattatgc
      901 ctgtaacgaa gtgtgaacca gaaaccaccc gcaaagcaag ccgtaaatat gcaaaaacgc
      961 aggaaacagt cctgtctgcc ctgctggcgc agacggagga agtgagtgtg ccgctggcct
     1021 cactgattaa atcaccgctg aatgtgcgca cggtgccgta ttctgcggag tccgtcagcg
     1081 aactggctga gtccattaag ggcgttggcc tgttgcagaa tctggtcgtg catac
//
LOCUS       DAPOXO010000253         1055 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.257, whole genome shotgun sequence.
ACCESSION   DAPOXO010000253 DAPOXO010000000
VERSION     DAPOXO010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1055
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.257"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            43..267
                     /locus_tag="ROH59_005185"
     CDS             43..267
                     /locus_tag="ROH59_005185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HDX4807535.1"
                     /translation="MGPQMITYTTRDGDRLDQICLAVYGRASKTTETVLYQVSNYGVT
                     DMCAVFRAGEKIVLPDIEPEPVKKETQLWD"
     gene            271..1055
                     /locus_tag="ROH59_005186"
                     /pseudo
     CDS             271..1055
                     /locus_tag="ROH59_005186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287093.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="late control protein"
BASE COUNT          313 a          224 c          278 g          240 t
ORIGIN      
        1 cgactactaa aattaattct cattatgaaa tccttttaat taatggggcc ccaaatgatt
       61 acatacacta cacgggacgg tgaccgtctc gatcagatct gccttgcggt ctacgggaga
      121 gcgtcaaaaa cgacagagac tgttttatat caggtttcga attacggcgt aacggatatg
      181 tgtgccgtgt ttcgtgctgg agaaaaaatt gttttaccag atatcgaacc agagccggtt
      241 aaaaaagaaa cgcaattatg ggattgatga atgagtgatt acgtaaatac tggcgtggag
      301 gcgtggaaac ctaattttta tatatctgct gataataaaa acatcacgga taaaataaga
      361 aaaggtttga tcaatatcac gctgacagat tacggcggct ccagtaaaca gacagacgaa
      421 ctccgcgtag caatagtttc tgaaactctg aaaattccgg cccgcggagt aaaaatcagt
      481 attgggctcg gtttcggtaa tcagataatt gataaaggga tatacatcgt tgacggtgct
      541 agcagtggcg gtgaaccccg ggtagttgat ttcacagcaa aagcggctcc gatgaacgca
      601 gcaaaaggat ctccgacagt tcagagcaaa aagactcgtt cctggagcga cgtcactgtc
      661 agcgatatcg ttgcgacaat agcgagcgat aatgggctaa aaccacgcgt atcaaagcgg
      721 tttgcagaca atgttatcac gcaactcgat caggtcggcg agtcagatat gcacctgatg
      781 tcgcggctcg caacgagatt cgatgcggtg agtaaacccg cgggcgggta ctggatattc
      841 ctgccgcgcg gcgcgggcga atctgttagc ggtgctccgc tccagcacta cacgctaact
      901 cgtcgtgata actccagctg gggctattcg agaaatggac aaagtggcga tagtggtagc
      961 ggtggcgaaa atccggaacc gacgtatctg attaaatatc acgacacagc aactgggcag
     1021 atcaaagaat tgcggacaag gtagtggcgg cgatc
//
LOCUS       DAPOXO010000254         1050 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.258, whole genome shotgun sequence.
ACCESSION   DAPOXO010000254 DAPOXO010000000
VERSION     DAPOXO010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.258"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            138..335
                     /locus_tag="ROH59_005187"
     CDS             138..335
                     /locus_tag="ROH59_005187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001753860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807536.1"
                     /translation="MQGAPHPARLKKNDGTTMACGGHWHTTPAQVKTEKTARHLQPKK
                     VKFLHFFSLIYRADLAIVMIK"
     gene            369..620
                     /locus_tag="ROH59_005188"
     CDS             369..620
                     /locus_tag="ROH59_005188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4807537.1"
                     /translation="MTGWELRIWRKSMLWSREKAAREFGVTQRTWHAWENAEQVDVTV
                     WRTTQALSVRDLLPHMQGMRKADIIRRLENELGETAEDV"
     gene            complement(651..857)
                     /locus_tag="ROH59_005189"
     CDS             complement(651..857)
                     /locus_tag="ROH59_005189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807538.1"
                     /translation="MTIAERLIQKGFDEGFDEGFKEGFKKGALEVAREAACRLRDMGW
                     TPERIQEAAGLSGEELKKLFPDEQ"
     gene            complement(919..>1050)
                     /locus_tag="ROH59_005190"
     CDS             complement(919..>1050)
                     /locus_tag="ROH59_005190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX4807539.1"
                     /translation="GRMEGALEKALAIACQLQKMGMTPEQIKQATGLSDDELKKIIH"
BASE COUNT          255 a          279 c          274 g          242 t
ORIGIN      
        1 ccctggacga ctgaaacggg atgtggtcgt gtatgtaccc ccggaaagtc cgtctgcgga
       61 gaacaggccg cagtgcggcg gcagacaggc agagacagct gcgccatcag gcgcagtggc
      121 cttacacacc gtaaggtgtg cagggagcgc cgcatccggc gcgactgaag aaaaacgacg
      181 gcacaacaat ggcatgtggt ggtcactggc acaccactcc cgcacaggtg aaaacagaga
      241 aaaccgcacg acatttacaa ccaaaaaaag tgaaatttct tcactttttt tcacttattt
      301 atcgcgctga tttggcaatt gtgatgataa aataaagtga ggttttttca ctttttcaaa
      361 ggtgttttat gactggctgg gaactgcgaa tctggcgaaa aagcatgctc tggtcacgcg
      421 aaaaagcggc cagagaattt ggcgtgacgc agagaacatg gcacgcctgg gaaaatgcgg
      481 aacaggtgga cgtcaccgtc tggaggacca cccaggcact ttcagtccgt gacctgctgc
      541 ctcacatgca ggggatgcgc aaggcagata tcatcaggcg tctggaaaat gaactggggg
      601 aaacggcaga ggatgtgtga gcgtgattca cagcctggca gaatgccagg ctactgctca
      661 tcaggaaaca gttttttcag ttcttcaccg gaaagtccgg ctgcctcctg aatccgttcc
      721 ggcgtccagc ccatatcccg cagccggcag gctgcttccc gcgccacttc aagcgcacct
      781 ttcttaaaac cttctttaaa accttcgtcg aaaccttcgt cgaaaccttt ctgtataaga
      841 cgttctgcaa tcgtcatact gttttctctg ctcctgctgg caaaaggccc ggtattttgc
      901 cgggctgtga ggttctcatc agtgaatgat tttcttcagt tcgtcatcgg aaagtccggt
      961 agcctgctta atctgctccg gcgtcatccc cattttctga agctggcacg caatagccag
     1021 ggctttttca agcgcacctt ccatcctgcc
//
LOCUS       DAPOXO010000255         1047 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.259, whole genome shotgun sequence.
ACCESSION   DAPOXO010000255 DAPOXO010000000
VERSION     DAPOXO010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.259"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            49..>1047
                     /locus_tag="ROH59_005191"
     CDS             49..>1047
                     /locus_tag="ROH59_005191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807540.1"
                     /translation="MAISQNFKTQVVFGGRIDPSFRRGTTELNDAIRQTSSTVGKLTK
                     SQDKLKDKIAAMKLAGKDVSDLSAQYQKLDRRIKATTQDQEALNTQLAKKQRLEKWTG
                     RAKGAAKWGGRAAAGAVRATGRGIKWGTLGAAGLIGGAAAGALAMNAETSEKLGLAKS
                     YGVGVEKYAAWENIGKAAGLNGENIGDLSEELTNKIGEIGNEKSLNPMLFQIGLTKKR
                     MAGWDREKQFNEVMRRISEMKDEKQAASLADQLMGGEANKIMTYMKATGKSWEQTMSD
                     AQKSNLLTKEGAEGAARAHVSVTNLWGSITSGLADTLGKIGGELAPTFDSVRETFTS"
BASE COUNT          312 a          208 c          315 g          212 t
ORIGIN      
        1 tgccgtaccg ggtttttaat ttctatgtaa acgaggtcat gaaaatcgat ggctatttct
       61 caaaacttta aaacgcaggt tgtattcggt gggcgaatag acccgtcgtt tcgtcgcggt
      121 acaacagaac tcaatgatgc gattcggcag acgtcgtcta ctgtcgggaa attaacgaaa
      181 agtcaggata aattaaaaga caaaatcgca gcaatgaaac tggcaggtaa agacgtttct
      241 gatttatctg ctcagtatca aaagctggac cgtcgaataa aagcgacaac gcaggaccag
      301 gaggcgctga atactcaact tgctaaaaaa cagcggctgg agaagtggac gggtcgcgca
      361 aaaggagctg caaaatgggg cggacgagcc gccgcaggtg cggtgagggc tacggggcgg
      421 ggtatcaaat gggggacact tggcgcggca gggctcattg gcggtgctgc agctggtgcg
      481 ctggcaatga atgcagagac gtcagaaaaa ctcggtctgg cgaagtccta cggcgttggc
      541 gtcgaaaaat acgctgcgtg ggaaaatatt ggtaaagccg cgggcctgaa cggcgaaaat
      601 atcggggatt tgtctgaaga acttacaaat aaaatcggcg aaatcggaaa cgaaaaaagc
      661 ctgaatccca tgttatttca aattggcctg acgaaaaaac gaatggctgg ctgggatcgg
      721 gaaaaacagt ttaatgaggt tatgcgtcgc atctctgaaa tgaaagatga gaagcaagcg
      781 gcgagcctcg ctgaccagct catggggggc gaggctaata agatcatgac gtatatgaag
      841 gcgacgggta aaagctggga acagacaatg tctgacgcgc aaaagtcgaa tttgttaaca
      901 aaagagggtg cggaaggggc ggcgcgtgcg catgtatcag tgacaaatct gtggggctct
      961 attacgtcgg gacttgcaga tacactcggt aaaatcgggg gggaactcgc gccgacgttt
     1021 gactcagtac gtgaaacatt tacatcc
//
LOCUS       DAPOXO010000256         1043 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.260, whole genome shotgun sequence.
ACCESSION   DAPOXO010000256 DAPOXO010000000
VERSION     DAPOXO010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.260"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..55
                     /gene="safA"
                     /locus_tag="ROH59_005192"
     CDS             <1..55
                     /gene="safA"
                     /locus_tag="ROH59_005192"
                     /inference="COORDINATES: protein motif:HMM:NF028383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HDX4807541.1"
                     /translation="GRMARDLTHFIINSLQD"
     gene            130..891
                     /gene="ydeO"
                     /locus_tag="ROH59_005193"
     CDS             130..891
                     /gene="ydeO"
                     /locus_tag="ROH59_005193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HDX4807542.1"
                     /translation="MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPY
                     ERHFKEIGFNENTIKKYLQCTNIQTVTMPVPAKFLRASNVPTGLLNEMIAYLNSEERN
                     HHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCL
                     YISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYA
                     FRKHFGNSPKRVSKEYRCQRHTGMNTDNTMNALAS"
BASE COUNT          332 a          201 c          200 g          310 t
ORIGIN      
        1 gggtcgcatg gcaagagatc ttacacattt cattatcaat agtttgcaag actgaaaata
       61 aacagcaaat tatacatgaa aaatgttaaa aaagtatcga taaaaacttt attattttaa
      121 ggagataaaa tgtcgctcgt ttgttctgtt atatttattc atcatgcctt caacgctaac
      181 attttagata aagattacgc cttctctgac ggcgagatcc tgatggtaga taacgctgtt
      241 cgcacgcatt ttgaacctta tgagcggcat ttcaaagaaa tcggatttaa tgaaaatacc
      301 attaaaaaat atctacaatg cactaacatc cagacagtga cgatgcctgt tcctgcgaag
      361 tttttacgtg cttcaaatgt accgactgga ttgcttaatg aaatgattgc ttatctcaac
      421 tcggaagaac gcaatcatca taatttttca gagcttttgc ttttttcttg cctgtctatt
      481 tttgccgcat gcaaaggttt cattacacta ttaactaacg gtgtgctatc cgtttccggg
      541 aaagtaagaa atattgtcaa catgaagctg gcgcacccat ggaagctgaa agatatttgt
      601 gactgcctgt acatcagtga aagcctgttg aagaaaaaac taaagcaaga gcaaacgaca
      661 ttctcacaga ttcttttaga tgccagaatg cagcacgcga aaaatttgat acgcgtagaa
      721 ggttcagtca ataaaattgc tgaacaatgc ggttatgcca gtacatctta ttttatttat
      781 gcgtttcgca aacatttcgg caacagtccg aagagagttt ctaaggagta ccgttgtcaa
      841 aggcacacgg gtatgaacac ggacaacacg atgaatgctt tagctagttg attatttgct
      901 aacgagtagt caaccacaca cgctgcgtaa gaattaaatg gggcagccat tccctgcccc
      961 gcgttgtttc caggcgatat atttcttgaa ataaataagt gacagccatc acatatttat
     1021 gcattttcat aacctgttgc atg
//
LOCUS       DAPOXO010000257         1042 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.261, whole genome shotgun sequence.
ACCESSION   DAPOXO010000257 DAPOXO010000000
VERSION     DAPOXO010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.261"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..773)
                     /locus_tag="ROH59_005194"
     CDS             complement(<1..773)
                     /locus_tag="ROH59_005194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HDX4807543.1"
                     /translation="MQRKTLLSACIALALSGQGWAADITEIETTTGEKKNTNVTCPAD
                     PGKLSPEELKRLPSECSPVVEQNLMPWLATGAATALITALAIVELNDDDDHHHRNNSP
                     LPPTPPDDNSDDTPVPPTPGGDEIIPDDGSDDTPTPPKPISFNNDVILDKTAKTLTIR
                     DSVFTYTENADGTISLQDSNGRKATINIWQIDEANNTVALDGVSADGATKWQYNHNGE
                     LVITGDNATVNNNGKTIVDGKDSTGTEIAGNNGKVIQDG"
BASE COUNT          291 a          216 c          217 g          318 t
ORIGIN      
        1 ataccgtcct gaataacttt cccgttatta ccggcgatct ccgtgccagt ggaatcttta
       61 ccatcaacga tggttttgcc attgttgttt actgtggcat tatcacccgt aataacaagc
      121 tcaccgttat gattatattg ccacttcgtt gcgccatctg cgctcacccc gtcaagggca
      181 accgtgttat tcgcttcatc aatttgccaa atattaatag ttgccttacg gccattgcta
      241 tcttgtagag aaatagtccc gtcagcattc tcggtataag taaaaactga atcgcgaata
      301 gttaacgttt ttgctgtttt atcgaggata acgtcattat taaacgaaat tggtttggga
      361 ggcgtcgggg tatcatccga accgtcgtct ggtattatct catctccgcc aggagttggg
      421 ggaactggag tgtcgtctga attatcatca ggtggagttg gtggaagtgg agaattattg
      481 cgatgatgat gatcatcatc gtcgtttagt tccactatgg ctaaggctgt gattaacgca
      541 gtagcagcac ctgtggcaag ccatggcatc aggttctgtt cgactacagg ggagcattca
      601 gagggtaagc gtttaagctc ttctggactg agttttccag ggtctgccgg acaagtcaca
      661 ttggtatttt tcttttcacc tgtggtggtt tctatctctg tgatatctgc cgcccagccc
      721 tgaccactca gagccaatgc aatacaggct gacaatagag ttttcctttg cataataaat
      781 ccttctggcg aatataaaga aggtcggatg ccttaaccca accaattaat caatcaatta
      841 aaacatagag gacattcaat attgccagta gattggcacc taatcaaaca tattctctga
      901 caatctgtaa ttataatttg agtgaatgaa tacacctgca taatatacaa cttgcgtata
      961 ttatatgaat tatagattta aatggcatca gataagcatt catttgataa aaaacggtac
     1021 aaatcaatac tcaaataaat aa
//
LOCUS       DAPOXO010000258         1039 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.262, whole genome shotgun sequence.
ACCESSION   DAPOXO010000258 DAPOXO010000000
VERSION     DAPOXO010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1039
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.262"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            138..335
                     /locus_tag="ROH59_005195"
     CDS             138..335
                     /locus_tag="ROH59_005195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001753860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807544.1"
                     /translation="MQGAPHPARLKKNDGTTMACGGHWHTTPAQVKTEKTARHLQPKK
                     VKFLHFFTLIFRVDLVIMMIK"
     gene            369..620
                     /locus_tag="ROH59_005196"
     CDS             369..620
                     /locus_tag="ROH59_005196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX4807545.1"
                     /translation="MTGWELRIWRKSMLWSREKAAREFGVTQRTWHAWENAEQVDVTV
                     WRTTQALSVRDLLPHMQGMRKADIIRRLENELGETAEDV"
     gene            complement(651..872)
                     /locus_tag="ROH59_005197"
     CDS             complement(651..872)
                     /locus_tag="ROH59_005197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014358130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807546.1"
                     /translation="MRTTKPGKIPGFFVSRSRANSMTIAERLIQKGALEVAREIACRL
                     WNMGWPPERIQEVTGLSGEELKKLFPDEQ"
     gene            complement(872..>1039)
                     /locus_tag="ROH59_005198"
     CDS             complement(872..>1039)
                     /locus_tag="ROH59_005198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX4807547.1"
                     /translation="GRMEGRMEGRMEGRMEGALEKALAIACQLQKMGMTPEQIKQATG
                     LSDDELKKITH"
BASE COUNT          246 a          274 c          276 g          243 t
ORIGIN      
        1 ccctggacga ctgaaacggg atgtggtcgt gtatgtaccc ccggaaagtc cgtctgcgga
       61 gaacaggccg cagtgcggcg gcagacaggc agagacagct gcgccatcag gcgcagtggc
      121 cttacacacc gtcaggtgtg cagggagcgc cgcatccggc gcgactgaag aaaaacgacg
      181 gcacaacaat ggcatgtggt ggtcactggc acaccactcc cgcacaggtg aaaacagaga
      241 aaaccgcacg acatttacaa ccaaaaaaag tgaaatttct tcactttttc acgcttattt
      301 ttcgcgttga tttggtgatt atgatgataa aataaagtga agttttttca ctttttcaaa
      361 ggtgttttat gaccggctgg gaactgcgaa tctggcgaaa aagcatgctc tggtcacgcg
      421 aaaaagcggc cagagaattt ggcgtgacgc agagaacatg gcacgcctgg gaaaatgcgg
      481 aacaggtgga tgttaccgtc tggaggacca cccaggcact ttcagtccgt gacctgctgc
      541 ctcacatgca ggggatgcgt aaggcagata tcatcaggcg actggaaaat gaactggggg
      601 aaacggcaga ggatgtgtga gcgtgattca cagcctggct gaatgccagg ctactgctca
      661 tcaggaaaca gctttttcag ttcttcaccg gaaagtcccg tgacctcctg aatccgttcc
      721 ggcggccagc ccatattcca aagccggcag gctatttccc gcgccacttc aagtgcgcct
      781 ttttgaataa gacgttctgc aatcgtcatg ctgtttgctc tgctcctgct gacaaaaaag
      841 cccgggattt tgccgggctt tgtggttctc atcagtgagt gattttcttc agttcgtcat
      901 cggaaagtcc ggtagcctgc ttaatctgct ccggcgtcat ccccattttc tgaagctggc
      961 acgcaatagc cagggctttt tcaagcgctc cttccatgcg tccttccatg cgtccttcca
     1021 tgcgtccttc catcctgcc
//
LOCUS       DAPOXO010000259         1031 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.263, whole genome shotgun sequence.
ACCESSION   DAPOXO010000259 DAPOXO010000000
VERSION     DAPOXO010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1031
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.263"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT          323 a          188 c          162 g          358 t
ORIGIN      
        1 gaagtattcc ttcctgagac ttgcattgca tgaaaagtta catcttcctt taaatatgat
       61 ttcattgctt cgacgaagcg tttagataca atgtgataag ctcctaagcc cttgaagtaa
      121 tctaaattgt ctaaatgctt atctgttaaa cctcgctgcg tagttccttt taaatgttta
      181 aaaaaatctc ttgcaaccgg tttactgtta aaaaggtaat tagatagtcg taatgataca
      241 ccatatgaga acattatata atgttctgca cttctgtttg ctgaacttag atgataagtt
      301 ttcatatctg gttctcttta aacttgggag aaggttacga cagtcgctct ctataaggac
      361 tgaagcgagg tggtcatttc ttatattccg tttaaccttg acgataaaac ggacatatca
      421 catcaacctt agccagatga ctccctccga taaaaacgga tagtctgcct gatcatctcc
      481 aaattgaata ctcggcataa ttatctaata aatatcgtaa atttatagaa attgatttat
      541 tgcattaact cgcgcaacat cttcaattaa tacgtctttt gcgacaatag ataattgctc
      601 ggaatatgct tcagagattt cattaagtat acaaaatgta tttttattaa tggttcattt
      661 tatctcatgt ccaactaaaa aaccgattgc ccttaatatg gttattgttg gatgttgtaa
      721 taattcctca accaatatat cctctgcttc atcaccaagc aatctataaa gcctcaaaca
      781 tgcagcataa tggtactcta ttgcattatc atcttctgaa gcttcaaaat tagaatgccg
      841 tattatatca actaatcctg ttgatattgt tttaatatca ctgtttgaga gaagaaattc
      901 atttgttttt attttgtcat atatgtttgg tgatgattat aaaaaatcta aagcccatag
      961 cccgacaagt atactggtaa cgtctttctg ttcagggcag atactggaaa catcccgcag
     1021 agacatgttt t
//
LOCUS       DAPOXO010000260         1025 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.264, whole genome shotgun sequence.
ACCESSION   DAPOXO010000260 DAPOXO010000000
VERSION     DAPOXO010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1025
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.264"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(191..823)
                     /locus_tag="ROH59_005199"
     CDS             complement(191..823)
                     /locus_tag="ROH59_005199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HDX4807548.1"
                     /translation="MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVKQTQKTAA
                     AERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKKT
                     NVNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVME
                     NQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
BASE COUNT          260 a          228 c          209 g          328 t
ORIGIN      
        1 aaatataaca taataaatga tttgtgataa tatgggatta ttgcggttta ctttgaggaa
       61 gataaaatgc gagtatatag aaccgcgagc gccaaataat tttatgacca caacctgtcg
      121 tattgtggtc ataaaaaatt gtcggctgga gggagttaaa tcctttacct caatatattg
      181 cctgtcaggt ttagttcaca aacagtgctt cgctatcaac gatgattcca tcttccgcac
      241 ctttaagcgc caggtttgcc tcgtagtatt gctttttatc aagcagtttc tgcgcatcag
      301 caagtgcatt acgagtctgt ttgagcggca tcagatattg gttttccatt acgccaacac
      361 cggccaggcg cagctcttcc attgcgccct ttttatcccc tttcgccatt ttttcgttgg
      421 caatttttat cgcggcttct ttttcgggtg tcgctacata actctcagaa attccgacag
      481 atgcattaat gacaatatat tggtcatcat tgacgttggt ctttttacct ggcttagcga
      541 actttgccca ttcggtacta tcatctgaca gcaaagcgga agcttcattg gtcagttctt
      601 ttgccttttc tggatcgcca tgaaacagag ccaggcgcgc tacctgcacg tcacgcatcg
      661 catataaacc ttgttcagag atacgctctg ctgctgccgt tttctgggtt tgcttaactt
      721 gctgagtttg ctgttgtgcc gctaccggtg cattatcagc agcccataca gttgaagatg
      781 ccagaattgc tgtgaccatc gtagccataa ttaaacgttt catacttacc tcattcttta
      841 acagttttag aaaacgccgc catcatattg ggtgagcatg aaatgagaaa tcagagagca
      901 acggtcattt tgaaagggtt atcttacaac tgtagttatt atcgcaaagc cgcttttagt
      961 cttacagttg taggaatctg cttcctgtcg cagagaacta ttcttatata ccacaaagat
     1021 atgtc
//
LOCUS       DAPOXO010000261          999 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.266, whole genome shotgun sequence.
ACCESSION   DAPOXO010000261 DAPOXO010000000
VERSION     DAPOXO010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.266"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..267
                     /locus_tag="ROH59_005200"
     CDS             <1..267
                     /locus_tag="ROH59_005200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HDX4807549.1"
                     /translation="NRDTWCRAGDYRAPGSLAGMIKQAWCSALGVDAGRYDTLAHFPV
                     RPAVWLERDDDTGFQQVLERADYLAKESTKAYGTGERNFGCSRG"
     gene            434..817
                     /locus_tag="ROH59_005201"
     CDS             434..817
                     /locus_tag="ROH59_005201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807550.1"
                     /translation="MYAKSFLALDGNGRLTGARTAQTAPYAHYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTEHAQQCPYVRPERREIRLIKRLQQFVPDALPVVRKASWYCRQC
                     HHDYYGEQYCTHCQTGRFSEEGVAE"
     gene            814..>999
                     /locus_tag="ROH59_005202"
     CDS             814..>999
                     /locus_tag="ROH59_005202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807551.1"
                     /translation="MNGIKTGLGITPGEHIISADSALSRNIRHCFCLSCHGRLILQTD
                     AQGAWFEHDLHALSEQQK"
BASE COUNT          224 a          270 c          292 g          213 t
ORIGIN      
        1 aaccgggata cctggtgtcg tgccggcgat taccgcgctc cgggatcact ggccgggatg
       61 attaaacagg cgtggtgcag tgccctggga gtggatgccg gacgttatga cacgctggca
      121 cattttccgg tcaggccggc ggtgtggctg gaacgcgatg atgacaccgg ctttcagcag
      181 gtgctggagc gtgctgacta tctggcgaag gagagtacca aagcttacgg caccggtgag
      241 cgcaactttg gctgcagtcg tggctgagcc cgacagacga cttatctgac cttagtgtga
      301 tgacgtgttc acagcgacca cactgatttt cccttctgag actgaactga aaaccgccat
      361 tcacacctga ccacgctgcc cgtaccggga cggctgttgc ctgtgtgtcg tctggcgcag
      421 aggaacatat actatgtacg caaaatcttt tctcgcactt gatggcaacg gacgtctgac
      481 cggtgcccgt accgcacaaa ctgctcctta tgcccactac acctgccacc tttgcggcag
      541 tgcactcaga taccacccgc aatacgacac cgaacggccc tggtttgaac acactgacga
      601 cgggctgacg gagcacgcgc agcaatgtcc ttatgtcagg ccggaacgca gagaaatacg
      661 gttgattaaa cgtctgcagc aattcgtccc ggatgcctta cccgtggtac gtaaagccag
      721 ctggtactgc aggcaatgtc accacgatta ttatggggag cagtactgca cacactgcca
      781 gaccgggcgt ttcagtgagg agggggtagc agaatgaacg gtataaaaac ggggctgggg
      841 atcacgccgg gtgagcacat tatcagtgcc gactctgcgc tcagcagaaa tatccggcat
      901 tgtttctgcc tttcctgtca tggccggttg attctgcaga cagatgctca gggggcgtgg
      961 tttgagcatg atttacatgc cctgagtgag caacagaag
//
LOCUS       DAPOXO010000262          934 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.267, whole genome shotgun sequence.
ACCESSION   DAPOXO010000262 DAPOXO010000000
VERSION     DAPOXO010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..934
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.267"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..498
                     /locus_tag="ROH59_005203"
     CDS             <1..498
                     /locus_tag="ROH59_005203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807552.1"
                     /translation="KLEWLIPDEKSDEEQKTYNDEYNRAYQEFMDSGGKYSPNAGLTA
                     DNIAKAKAEEAVENMRHPERQEQAKSQAESMLAFVNPLSGMVNKNTAPAALDSSTLNI
                     DTLKQAVSTPAPEQNNKIEINIVGATDPQSIQQSAASGVLDGLRQAASSYNRGAMFDK
                     PAAAG"
     gene            534..923
                     /locus_tag="ROH59_005204"
     CDS             534..923
                     /locus_tag="ROH59_005204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX4807553.1"
                     /translation="MLGLGDFIFAISTVAYNKLQRSDAWRWAQQTRFGKNDALQITGR
                     PNPTITIDGKINALFLDGCGVGLLTDLRALGNTGEPQQLVLGTGEVKGYWVLRELTET
                     QNSFLMGGTPKSQDFSLTLEYYGASLD"
BASE COUNT          285 a          197 c          251 g          201 t
ORIGIN      
        1 aaactggagt ggcttattcc ggatgaaaaa tcagatgaag aacagaaaac ttataatgac
       61 gaatataatc gggcatatca agagtttatg gattcgggag gtaaatattc accgaacgct
      121 ggattgactg ctgataatat tgcgaaggca aaagccgaag aggctgtcga aaatatgcgg
      181 catccagaac ggcaagaaca ggcaaaatct caggcagaat caatgctcgc gtttgttaat
      241 ccattatccg ggatggtaaa taaaaatacc gcgcctgcag cactggattc gtcgacgtta
      301 aatattgata cgttgaagca ggcagtctcg acacctgcgc cggagcaaaa caataaaatc
      361 gaaatcaata ttgtcggtgc gacagatccg cagtcaatac aacaatctgc agcgtcgggg
      421 gtgctcgatg gactgagaca ggctgcgagt tcgtacaatc gtggcgcgat gtttgataaa
      481 ccagctgcgg cggggtgaca atgagtgatg caataaacgg tgctgaggat atcatgctcg
      541 gcctgggtga tttcattttt gctatatcaa cagtagcgta caacaaactg caacgtagtg
      601 acgcctggcg ctgggctcag caaacacgat tcgggaaaaa cgacgcgttg cagataaccg
      661 gacgaccgaa ccccacaatt actatcgatg gaaagataaa cgctttattt cttgacgggt
      721 gcggcgtcgg cctgttgaca gatttgcgag cgctcgggaa cacgggagaa ccccagcagc
      781 tagtgctggg gaccggggag gtgaaagggt actgggtgct gcgagaacta actgaaacgc
      841 aaaacagctt tttgatgggc ggaacaccta aatcgcagga cttttcactc acgctcgaat
      901 attatggagc ttcgctagat taatacaaaa tcaa
//
LOCUS       DAPOXO010000263          923 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.268, whole genome shotgun sequence.
ACCESSION   DAPOXO010000263 DAPOXO010000000
VERSION     DAPOXO010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.268"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(147..>923)
                     /gene="bla"
                     /locus_tag="ROH59_005205"
     CDS             complement(147..>923)
                     /gene="bla"
                     /locus_tag="ROH59_005205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase"
                     /protein_id="HDX4807554.1"
                     /translation="VKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKV
                     LLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDN
                     TAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTL
                     RKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAA
                     LGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW"
BASE COUNT          234 a          228 c          207 g          254 t
ORIGIN      
        1 gggtctgacg ctcagtggaa cgaaaactca cgttaaggga ttttggtcat gagattatca
       61 aaaaggatct tcacctagat ccttttaaat taaaaatgaa gttttaaatc aatctaaagt
      121 atatatgagt aaacttggtc tgacagttac caatgcttaa tcagtgaggc acctatctca
      181 gcgatctgtc tatttcgttc atccatagtt gcctgactcc ccgtcgtgta gataactacg
      241 atacgggagg gcttaccatc tggccccagt gctgcaatga taccgcgaga cccacgctca
      301 ccggctccag atttatcagc aataaaccag ccagccggaa gggccgagcg cagaagtggt
      361 cctgcaactt tatccgcctc catccagtct attaattgtt gccgggaagc tagagtaagt
      421 agttcgccag ttaatagttt gcgcaacgtt gttgccattg ctgcaggcat cgtggtgtca
      481 cgctcgtcgt ttggtatggc ttcattcagc tccggttccc aacgatcaag gcgagttaca
      541 tgatccccca tgttgtgcaa aaaagcggtt agctccttcg gtcctccgat cgttgtcaga
      601 agtaagttgg cagcagtgtt atcactcatg gttatggcag cactgcataa ttctcttact
      661 gtcatgccat ccgtaagatg cttttctgtg actggtgagt actcaaccaa gtcattctga
      721 gaatagtgta tgcggcgacc gagttgctct tgcccggcgt caacacggga taataccgca
      781 ccacatagca gaactttaaa agtgctcatc attggaaaac gttcttcggg gcgaaaactc
      841 tcaaggatct taccgctgtt gagatccagt tcgatgtaac ccactcgtgc acccaactga
      901 tcttcagcat cttttacttt cac
//
LOCUS       DAPOXO010000264          917 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.269, whole genome shotgun sequence.
ACCESSION   DAPOXO010000264 DAPOXO010000000
VERSION     DAPOXO010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.269"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(183..908)
                     /locus_tag="ROH59_005206"
                     /pseudo
     CDS             complement(183..908)
                     /locus_tag="ROH59_005206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639415.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
BASE COUNT          297 a          198 c          111 g          311 t
ORIGIN      
        1 cggtcctaat atttcaatgg aaatatttct cttcgataat gcctttagca tataataagg
       61 tgtgccagac caactggatg tagatagtgg atcataagca gataaaaaag ccactttcat
      121 taaataccct ttaataacat atcaaactat agatttatta acaccatgat taagtgcata
      181 ttctaatggc atttgctacc tttgtttcgt ttgaagttaa acataacatt caaacatctt
      241 ttcatcttat taaactcacc tcttctagca cggttaaatg ctacaacaaa aagtgacaac
      301 cataccgtcc aataatattg gggataaaac ctttctgtaa tgaccagcct attttttatt
      361 gagcaaagat cagccatcat gctctttccc ccatcagtac ttgcacctat tttatgataa
      421 accaaacttt ctgagcaaat acctaattta aagttctttg cttttgctct gaggcaaata
      481 tctaactctt catagtataa aaaatattct tcattcatca atccaactgt ttccaaacat
      541 tctctagaga aaaacatcga tgcgccaatt atataatcta tatcattact aatgacttca
      601 tcatcatatt ttttggaaac taatcttccc atttcataat tttttgtagt gcataaccat
      661 ttgttatgca ccccacctag tccttgctgc atctctctgt cggcaaaata gactaaacga
      721 gaaccgcaaa tccctatact tttatctgaa tcacatttac taattaaatg agttaaagcc
      781 tctttatcca cttcagtatc attattcaga acccagacgt atttcatatt ctcctgatta
      841 agagcgaact ctatgccaat attattacca cttgcgtacc cattattttg cggagattgg
      901 gtaatgactc caactta
//
LOCUS       DAPOXO010000265          902 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.270, whole genome shotgun sequence.
ACCESSION   DAPOXO010000265 DAPOXO010000000
VERSION     DAPOXO010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.270"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(401..902)
                     /locus_tag="ROH59_005207"
                     /pseudo
     CDS             complement(401..902)
                     /locus_tag="ROH59_005207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012016515.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
BASE COUNT          301 a          148 c          193 g          260 t
ORIGIN      
        1 tgctggaggt aaatagtgtg aacagcatta gtttgatgat tttatactga actaaagggg
       61 gaaagaggta acgaaaaaag acctccacca ggtacgaatc tgaggcgggc agatggaggt
      121 cgatatctac ccgattaaat ggataagtaa aagccccatc agggattgat ttgttcgagt
      181 ctaatttaaa gtaatttcaa cgatttggca gaacttctta gagttaatga ttttcaagtt
      241 ttcgattacc aggaaaaagg ctgggggctg ataaaatagt catctgcatt ccttaaattg
      301 tgtaagggtg aaaggataaa gttcaattta aaggcggtac aatattagca ccatcttata
      361 tatgtaatga ttgatttgcc tctttattct actgttgaga ttattgtttc cgaaaattga
      421 ttattatcag cgcgaaaaga aatgctacag caaataagag gacgattgtc ggcgctgggg
      481 ctctgttgag aaaatataat aaccatacgc ctgatattgt tattgatatc gttacggcga
      541 taagtaatgc cttatgaaag cgatgcatga tgaggacagc aatagaccct ggagctatta
      601 atagtatata gacagaataa ttccgactgc ttttaatgtg gcaaaaatgg taggcgatac
      661 catgcagagt aaaccgtaat gtaataatga tatctgtaat ccgctgactt gtgcctgttg
      721 atagtcaaga caaaaattcc tgaaaaaacg atacctataa tggtatcttt ctttataatg
      781 ctattatctt tcagatagcc agttgcaatt gcacaagaca gtcctacaat aaatgcacca
      841 attcccagcg gcatacctat aatccagact agaactatgc caggaaacat tgcgtggctc
      901 at
//
LOCUS       DAPOXO010000266          887 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.271, whole genome shotgun sequence.
ACCESSION   DAPOXO010000266 DAPOXO010000000
VERSION     DAPOXO010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..887
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.271"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            85..276
                     /locus_tag="ROH59_005208"
     CDS             85..276
                     /locus_tag="ROH59_005208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807555.1"
                     /translation="MNISTETREILRNYRAVINARRRELGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(610..678)
                     /locus_tag="ROH59_005209"
                     /pseudo
     CDS             complement(610..678)
                     /locus_tag="ROH59_005209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilus protein"
BASE COUNT          157 a          275 c          279 g          176 t
ORIGIN      
        1 cgggggcgac ggtgacgcat tcgtcaggga ggaacgcgaa gcaatgaacg ttgtattgca
       61 ggcgctggac ggggagacga tgtcatgaat atcagcacag aaacccgcga aattctgcgt
      121 aattacaggg ccgtgattaa tgcgcggcgt cgtgaattgg ggcagaaacc gctcaccacc
      181 gcgcagattg ttgatgaaat ctgcgatttt gtggcgaatc agcaggcggt tttcctcggt
      241 ggtcactaca tccttcaggg cagcagaaac aggtgataca ggggcaggcg gtggaggccg
      301 cctgtcagcc cgcgcgaaaa cccctggcag gctgacgcct gccggaaatg cggggtgcag
      361 cgcctgcggc gctgccggcc cggctttccg gtcagaaggt agtgtatggc tgtatgcagg
      421 gaacaggtgt gatgttccgt gacactgtca ccgtttctgg ctgtctttta ttgcgcccac
      481 ttcggctccc ggctgcctgg cggcatccgg tcgtcaggcc cgactccgac aggcagctgc
      541 tggcgcaccc gccagtctcc gccgaacccg ctggcgcggt ttcgggctgt cgctacggtc
      601 cgatgcgtga aaacccgggc ttgcagcgac cgttccggtc gcaccgcccc tgtcgcgccg
      661 tgacctgcgc tccctgcaca cctgacggtg tgtgaggaaa ctgcgcctga tggcgcagca
      721 gtcctccctc ctgccgccac ccctgcggcc tgtttcccgc tgtggacttt ccggggggca
      781 gacgtaaccc cctcccgttc catctgtcca gggtgagatg caccggccac aaaattttta
      841 gccatgaacc cggctaaaaa ttttgcgtcc gcccccggac agctgtc
//
LOCUS       DAPOXO010000267          885 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.272, whole genome shotgun sequence.
ACCESSION   DAPOXO010000267 DAPOXO010000000
VERSION     DAPOXO010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..885
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.272"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(80..775)
                     /gene="aqpZ"
                     /locus_tag="ROH59_005210"
     CDS             complement(80..775)
                     /gene="aqpZ"
                     /locus_tag="ROH59_005210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HDX4807556.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRN"
BASE COUNT          289 a          240 c          194 g          162 t
ORIGIN      
        1 gagcgcaaca agatgatgaa tcaacatata acaacatctt aaaaaaaggc ctgacattgc
       61 gccaggcctt ctgcgttaat taattacgct tttccagtag agtccggtaa atcagaccac
      121 cgataatacc gccgacaatt ggcaccaccc agaagaacca cagttgttct aatgcccagc
      181 cgccctggaa gatagcaacc gcagtactgc gcgccgggtt aacggaagtg ttagtcaccg
      241 gaatactgat taagtgaatc agggttaagg ccagaccaat ggcaattggc gcaaaaccag
      301 caggagcgaa tttgtcagtt gcgccgtgga tcaccagcag gaaacctgca ctcaatacca
      361 gttcaactac cagcgcggaa agcatggaat aaccgcctgg tgaatgctcg ccataaccgt
      421 tagaagcaaa accgctggct gccgcgtcaa aacccgtttt accactggca attaaataca
      481 gcagcgccgc cgcaacaata ccgccgacaa cctgggcaat tacgtagcca acgacttctt
      541 ttgccgggaa acgtccgcca gcccataaac caatagtgac cgccgggtta aaatgaccac
      601 cagaaatatg accaacagca aaggccattg tcagaacggt cagaccgaac gccaacgcca
      661 cgccggcaaa accaatgcct aattccggga agcctgcggc cagtacggca ctaccacagc
      721 cgccaaaaac aagccagaaa gtaccaaaac attcagctgc taattttctg aacatatcca
      781 cctcaattaa aaattgaccc tgtgaaaaat atggtcgttt tatagggtcg tcgtaaaaaa
      841 gtgacgacgg aaataatgcg cggctatttt aaaaacgaag gcaaa
//
LOCUS       DAPOXO010000268          842 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.273, whole genome shotgun sequence.
ACCESSION   DAPOXO010000268 DAPOXO010000000
VERSION     DAPOXO010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.273"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(291..>842)
                     /locus_tag="ROH59_005211"
     CDS             complement(291..>842)
                     /locus_tag="ROH59_005211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296213.1"
                     /note="WbbJ; catalyzes the transfer of the O-acetyl moiety
                     to the O antigen; part of the lipopolysaccharide
                     biosynthetic pathway; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDX4807557.1"
                     /translation="LRLLKDIFLTKFLFCSNVRIIRFPCYIRKDGSVSFGKGFTSGVG
                     LRVDAFMDAVVSIGENVQINDYVHIAAINNVIIGRDTLIASKVFISDHNHGIFSKSDI
                     HSSPTIIPSSRPLESAPVYIGERVWIGENVTILPGACIGNGVVIGANSVVRGEIPNNV
                     IIAGVPAKIVKKYNYERMQWERI"
BASE COUNT          292 a          174 c          115 g          261 t
ORIGIN      
        1 gggtacacta acatttgctg taatatcatg taagcatacc caatgagttg ccttaatcac
       61 cttagataat ctattgcaag ttatatattc gaaatataat cttttaaccc acgaagactt
      121 gacttctgga tactctataa attcaaccca cggaaataat tccattagtt cagcagagct
      181 atgaaccagt gcaataaatt tacattcggc tctatcttta gttgctgtaa gcacattttt
      241 tagtacggta aaggggcctc cggttgtaaa attaacagcc gatattacaa ctatattctt
      301 tcccattgca tacgctcata gttatatttt ttaacaattt tagctggaac accagcaatg
      361 atcacattat taggaatctc accacgaaca acactgtttg cgccaataac tacaccatta
      421 cctatacacg cacctggtaa tattgtcaca ttttcgccaa tccacacacg ctctccaata
      481 tacacaggtg cagattcaag gggcctagac gaaggaataa tagttggtga actatggata
      541 tcggatttag aaaaaatacc atgattatga tcactaataa atactttact tgctattaat
      601 gtatctctac caataatgac attattaata gccgcgatgt gaacatagtc attaatttga
      661 acattttctc caatggaaac tacggcatcc ataaatgcat caactcgtaa tcctacacct
      721 gatgtaaaac cttttccaaa actaacactt ccatcttttc taatataaca tggaaatcta
      781 ataatcctaa catttgaaca aaataaaaat tttgttaaga atatatcttt aagaagccta
      841 ag
//
LOCUS       DAPOXO010000269          817 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.274, whole genome shotgun sequence.
ACCESSION   DAPOXO010000269 DAPOXO010000000
VERSION     DAPOXO010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.274"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT          229 a          191 c          169 g          228 t
ORIGIN      
        1 tggaaatcat catcagcgtc gatatggacg aatataaaaa catttacgtt atatcccaaa
       61 aacacacagg tcttagggag gtttaaactg tgtattaaca cctatcgtat tgacgggcgt
      121 gaaatggcag aaacagaagt cgttcctatt gacatgcctg actctaacgg cgagatgact
      181 tggcaagcca aaaactacac acagtattcg tcctacttta tgaagattac ttgcttgaaa
      241 tagcttattg gcaaatggca tatacagtta ttgaaccatt ctgatcttcg gttgtatcgc
      301 acgcagccga ccatgagtta ttggctgatg ggaatgacct ggtaagccat atgtaaccag
      361 ttcgtgaggt gcatattccg ccgccacctg taacacgttt tccagttgga caggtagctg
      421 ttgctccagg aaagcgccaa cctgtggcct gtgctgtagc aatttgaagc tcaccagatc
      481 ctacctttct ccaggtaccg gattggcacg taggccagca gcgccagcaa tttaatctca
      541 gttctgacac gcgacgacat aactacattt tccggttaaa tcagctctaa atgtcccttt
      601 atggaaattg tattcatcat aaaaaccaca tttaacaatt cgatttgcat cataagttgc
      661 aactgatccc gcaaagtaat tcggcttcca gccttgaggg ttttctgcat tgctcacact
      721 ccatgagcac tgactggcag aaaatcctgt tggcagcggt atttgctgac catttgctat
      781 acgaccagtt atcaccgtac taccagaatt gctttta
//
LOCUS       DAPOXO010000270          816 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.275, whole genome shotgun sequence.
ACCESSION   DAPOXO010000270 DAPOXO010000000
VERSION     DAPOXO010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..816
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.275"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..216
                     /locus_tag="ROH59_005212"
     CDS             <1..216
                     /locus_tag="ROH59_005212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="late control protein"
                     /protein_id="HDX4807558.1"
                     /translation="KEAAPGLKGGAAKKEFSMTYTTPATLDLVSLTAECKVTTQGFGT
                     EEDRDWTINTLSLTLAENGFSVRLSLE"
     gene            383..802
                     /locus_tag="ROH59_005213"
     CDS             383..802
                     /locus_tag="ROH59_005213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807559.1"
                     /translation="MVVKNGLACGIMLALVGCATKPVSNEQATPVPEKQIISTALLEK
                     RDGTGEVIIKRDSGFFGSACFSRVYVDGKEVADLGTAQKVVVYPTIGDHVFSAWPKGV
                     CGGGMSEQAGKVTTDRTLMYRIGYGSNGEYGIHPTAF"
BASE COUNT          214 a          159 c          230 g          213 t
ORIGIN      
        1 aaagaagctg caccagggct caagggcggt gcagctaaaa aagagttctc tatgacgtac
       61 acgacgccag cgacgctcga tttagtgtcg ctgacagcag aatgcaaagt cacaactcaa
      121 ggtttcggga ccgaggagga ccgggactgg actatcaaca cactgagtct gacgctcgct
      181 gaaaacggtt tttcggttcg gctgtctctg gagtaaatgg gctcggcgag ccggtggcgg
      241 tatgaattta gtattaacag atgtcgactg caaacggcac ctgcgatatt tttaggcgta
      301 agccggagaa cgaagagtct ctggtgctga acgttgttat cgttagatgc tgacatattt
      361 ttaatattgg gagttttcaa acatggtcgt taaaaatggt cttgcctgtg ggattatgct
      421 tgctcttgtc ggttgtgcta caaaacctgt ctcaaatgaa caagccactc ctgttcctga
      481 aaaacaaatt atcagtaccg cgttactcga aaaacgagac ggtacgggag aggtgatcat
      541 caagcgtgac tcgggtttct ttggaagcgc gtgtttttcc cgtgtttatg ttgatggtaa
      601 agaggtggca gatttaggta cagctcagaa agtcgttgta tacccaacga ttggtgatca
      661 tgtcttcagc gcgtggccaa aaggagtatg tggtggtggc atgagcgaac aagcgggcaa
      721 ggtgacaaca gatcgtactt tgatgtatcg catagggtat ggatcaaacg gtgaatatgg
      781 aattcaccca accgcgtttt aatttgtgtt ggggta
//
LOCUS       DAPOXO010000271          809 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.276, whole genome shotgun sequence.
ACCESSION   DAPOXO010000271 DAPOXO010000000
VERSION     DAPOXO010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.276"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(237..761)
                     /locus_tag="ROH59_005214"
     CDS             complement(237..761)
                     /locus_tag="ROH59_005214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HDX4807560.1"
                     /translation="MFSKNKITIAAISALLISGTAMAQTSSGSVSATGSFNAATCSVT
                     LPNATASFGTVTNQEVNAAKAYQKIKSVTADQGISVTDCTTPASLTVATTNFQSNGYV
                     YPALNEATGNQQKDFALWMKVGDKGVSSYNAPIELANGTYPIELQMIKISNNYNKNHT
                     GAWSAQYTLTATYN"
BASE COUNT          245 a          141 c          150 g          273 t
ORIGIN      
        1 atgctcgcaa tagccagttt ttatctgtgt tattattgaa ctttacttta gtacttaagt
       61 cattactatc aaatataact ctggtagtat caagataaat accaccagtc tcagctagcg
      121 aaatatgaga aaaaaatatg aaagataata ttgtaatatt gtattttttc attttatatt
      181 gtcacattaa agaatgctga atatacaggc atgagtaatc atgcctgtta aatatattag
      241 ttataagttg cagtcaaagt gtattgcgca ctccatgcac cagtatgatt tttattgtag
      301 ttatttgata ttttaatcat ttgcaactcg attggatatg taccattagc aagttcgatt
      361 ggtgcattat aagaagatac acctttatca ccgactttca tccaaagcgc aaaatccttt
      421 tgttgattac cggtagcctc gtttagagca ggataaacat agccattaga ctggaaatta
      481 gtagttgcta ccgttagtga tgcaggagtg gtacaatcgg taacactaat cccctgatct
      541 gcggttacac tttttatttt ctggtacgct tttgcagcat ttacctcttg attcgttact
      601 gtgccaaaag atgctgttgc attaggcagg gtaacactgc aagtcgcggc attaaaagaa
      661 ccagtagcgg agacagaacc actgcttgtc tgggccattg cggtaccaga aataagcaga
      721 gccgaaatag ctgcgatggt gattttattc ttagaaaaca ttttcaacct caatcttgat
      781 tttcttaaat ttttcctatg tgtatagtg
//
LOCUS       DAPOXO010000272          783 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.277, whole genome shotgun sequence.
ACCESSION   DAPOXO010000272 DAPOXO010000000
VERSION     DAPOXO010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.277"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>783
                     /gene="vgrG"
                     /locus_tag="ROH59_005215"
     CDS             <1..>783
                     /gene="vgrG"
                     /locus_tag="ROH59_005215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX4807561.1"
                     /translation="FRFATDARLKIEVVEFYDDQSGYERGLTLPLRHPSGLFDGETEA
                     VWGLNTAYSVVEKSVTTRDYNYRTATAEMMTEQHDATGGDNTTYGEAYHYADNFLQKG
                     DKEAAESGAFYARIRHERYLNEQAILKGQSTSSLLMPGLEIRVQGDDAPAVFRKGVLI
                     TGVTASAARDRSYELTFTAIPYSERYGYRPALIPRPVMAGTLPARVTSTVKNDIYAHI
                     DKDGRYRVNLDFDRDTWKPGYESLWVRQSRPYAGDTYGLHLP"
BASE COUNT          179 a          239 c          234 g          131 t
ORIGIN      
        1 ggttccgctt tgccaccgac gcccggctga aaatcgaagt tgtcgagttt tatgacgacc
       61 agagcggcta cgagcgcggg ctgacactgc cgcttcgcca tccttcaggg ctgtttgatg
      121 gtgaaacgga agcggtatgg gggctgaata ccgcgtacag cgtggtggaa aaaagcgtca
      181 ccactcggga ctacaactac cgcaccgcca cagcagagat gatgacagag cagcatgacg
      241 ccaccggggg cgataacacc acctacggcg aagcctacca ctatgccgac aacttcctgc
      301 aaaaaggcga taaagaggca gcggaaagcg gcgcgtttta tgcccgtatc cgccacgaac
      361 gctacctgaa tgaacaggcc attctcaaag gccagagcac cagttcactg ctgatgccgg
      421 ggctggaaat cagggttcag ggcgacgacg cgccagcagt gttccgcaag ggcgtactga
      481 ttaccggcgt gacggccagc gcggcgcgtg accgcagcta tgagctgacg tttaccgcca
      541 tcccgtactc agagcgctac ggctaccgcc cggcgcttat cccccgcccg gtaatggccg
      601 gcacactccc ggcgcgggtc accagcacgg tgaaaaacga tatctatgcc catatcgaca
      661 aggacgggcg ctaccgggtc aacctcgact ttgaccgcga tacgtggaaa ccgggttatg
      721 aaagcctgtg ggtgcgccag tcgcgcccgt atgcaggtga cacgtatggc ctgcatctgc
      781 cgc
//
LOCUS       DAPOXO010000273          779 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.278, whole genome shotgun sequence.
ACCESSION   DAPOXO010000273 DAPOXO010000000
VERSION     DAPOXO010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..779
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.278"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(32..736)
                     /locus_tag="ROH59_005216"
     CDS             complement(32..736)
                     /locus_tag="ROH59_005216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="HDX4807562.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
BASE COUNT          178 a          206 c          200 g          195 t
ORIGIN      
        1 atgaggcagc cttttgtctt attcaaaggc cttacatttc aaaaactctg cttaccaggc
       61 gcatttcgcc caggggatca ccataataaa atgctgaggc ctggcctttg cgtagtgcac
      121 gcatcacctc aatacctttg atggtggcgt aagccgtctt catggattta aatcccagcg
      181 tggcgttgat tatccgtttc agtttgccat gatcgcattc aatcacgttg ttccggtact
      241 taatctgtcg gtgttcaacg tcagacgggc accggccttc gcgtttgagc agagcaagcg
      301 cgcgaccata ggcgggcgct ttatccgtgt tgatgaatcg tgggatctgc cacttcttca
      361 cgttgttgag gattttaccc agaaaccggt atgcagcttt gctgttacga cgggaggaga
      421 gataaaaatc gacagtgcgg ccccggctgt cgacggcccg gtacagatac gcccagcggc
      481 cattgacctt cacgtaggtt tcatccatgt gccacgggca aagatcggaa gggttacgcc
      541 agtaccagcg cagccgtttt tccatttcag gcgcataacg ctgaacccag cggtaaatcg
      601 tggagtgatc gacattcact ccgcgttcag ccagcatctc ctgcagctca cggtaactga
      661 tgccgtattt gcagtaccag cgtacggccc acagaatgat gtcacgctga aaatgccggc
      721 ctttgaatgg gttcatgtgc agctccatca gcaaaagggg atgataagtt tatcaccac
//
LOCUS       DAPOXO010000274          767 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.279, whole genome shotgun sequence.
ACCESSION   DAPOXO010000274 DAPOXO010000000
VERSION     DAPOXO010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.279"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>767
                     /gene="wzy"
                     /locus_tag="ROH59_005217"
     CDS             <1..>767
                     /gene="wzy"
                     /locus_tag="ROH59_005217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_158642102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O25 family O-antigen polymerase"
                     /protein_id="HDX4807563.1"
                     /translation="LFILLCFNCLLSMLFNIEQALTFKVVLSIYSILIMAYVSSCYAQ
                     TLWLCSEEILKRSVFYLFAFLCLIGIISILLQKTEIIHDKSMILFPEPSAFALVFIPI
                     FSFCLYYTRGGGLLLLYILSLGIALGIQNLTMLVGIVISVFVMKKITIRQTIVILLGA
                     WIFSMILSDLDISYYTSRLDFKNTTNLSVLVYLSGIERAFLNFITSYGLGIGFQQMGV
                     NGEIGIYQQILAELDAPMLNIYDGSFISSKLISEFGV"
BASE COUNT          214 a          101 c          142 g          310 t
ORIGIN      
        1 cgttattcat attgttgtgt tttaactgtt tgttaagtat gctatttaat attgaacagg
       61 ctttaacatt taaagttgta ctttcaatat atagcatctt aataatggca tacgtctcct
      121 cttgttatgc acagacgttg tggttatgtt ctgaagaaat acttaagaga tccgtctttt
      181 atttgttcgc atttctttgc cttattggca ttataagtat tcttttacag aagactgaga
      241 ttatacatga taaaagtatg attctttttc ctgaaccatc agcatttgca ttggttttta
      301 tacctatctt ttcattttgt ttatactata caagaggggg ggggctacta ttgctctata
      361 tattatcttt gggtattgcg ttaggtatcc agaatttaac aatgttggta ggcattgtga
      421 ttagtgtttt tgtgatgaaa aaaataacta taaggcaaac tattgttata cttttggggg
      481 catggatttt ttccatgata ttaagtgatt tagacatttc ttactataca tcgcggcttg
      541 attttaaaaa tactacgaac ctatcagtgc ttgtatatct ttcaggaatt gaaagagctt
      601 tcttgaattt tattacaagt tatggtcttg gtattggttt tcaacaaatg ggagtgaatg
      661 gggagatagg aatatatcaa caaattttag ctgaacttga tgcccctatg ttaaatatat
      721 acgatggctc atttatttct tctaagttaa tatctgagtt tggggtt
//
LOCUS       DAPOXO010000275          765 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.280, whole genome shotgun sequence.
ACCESSION   DAPOXO010000275 DAPOXO010000000
VERSION     DAPOXO010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.280"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>765
                     /locus_tag="ROH59_005218"
     CDS             <1..>765
                     /locus_tag="ROH59_005218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HDX4807564.1"
                     /translation="RDKNIVFNIDIENFFPSFNFGRVRGYFIANQNFKLHPNVATIIA
                     QIACLDGSLPQGSPCSPVITNLICRILDFRLSKLAVTYGCSYSRYADDITFSTNKKNI
                     PDALVSNEKENEPGKILVEEIHRAGFTLNHNKNRVSRCTSRQQVTGLTVNKKINVSRE
                     YIKNTRAMAHSLYFEGSYTLIEKDGKHRKGTLSELEGRFAFIDMLDKYNNVEAKKNAR
                     PERYVVKGFGLDFKQRLNSREKAYSKFLYYKNFYGN"
BASE COUNT          277 a          116 c          150 g          222 t
ORIGIN      
        1 atcgagataa aaatattgta tttaatattg atattgagaa tttcttccca tcctttaatt
       61 ttggtcgcgt gcgaggatat tttattgcaa accaaaattt caagttacat ccaaatgttg
      121 caaccattat tgcgcagata gcctgcctgg atggatcgct tccgcaagga agcccttgtt
      181 ctccagtaat aactaatctt atttgtagga ttttagattt cagattatca aagctagcag
      241 tcacatatgg ttgtagttac agccgctatg cagatgacat tacgttttca acaaacaaaa
      301 aaaacatccc tgatgcatta gtttctaatg agaaagaaaa cgaaccaggt aagatattgg
      361 tagaagaaat tcatcgtgca ggcttcactt taaaccataa taaaaacaga gtgtctaggt
      421 gtacatcaag acagcaagtt acaggtttaa ctgtaaataa aaaaataaat gtaagcagag
      481 agtatataaa gaatacaaga gcgatggcgc attctttata ctttgaaggt tcgtatacac
      541 ttattgagaa agatggaaaa catagaaagg gcacccttag tgaattagaa gggcgatttg
      601 catttatcga tatgcttgat aaatataata atgtggaagc aaagaaaaat gcgcgtcctg
      661 agagatatgt ggttaaagga tttgggttgg attttaagca gagacttaac tccagagaga
      721 aagcatacag caaattccta tactataaaa atttctatgg aaatg
//
LOCUS       DAPOXO010000276          738 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.281, whole genome shotgun sequence.
ACCESSION   DAPOXO010000276 DAPOXO010000000
VERSION     DAPOXO010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..738
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.281"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>738
                     /locus_tag="ROH59_005219"
     CDS             <1..>738
                     /locus_tag="ROH59_005219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDX4807565.1"
                     /translation="LNKKTIINDEDASLIERKAIEKATVVSFPSKWAMDFCRNYYRLD
                     FDKLVEIPWGANLFDDIHFANKNIIQKNSYTCLFLGVDWERKGGKTALKAIEYVRQLY
                     GIDVRLKICGCTPNQKILPTWVELIDKVDKNNVDEYQKFIDVLSNADILLLPTIAECY
                     GMVFCEAAAFGLPVVATDTGGVSSIVINERTGILIKDPLDYKHFGNAIHKIISSVETY
                     QNYSQNARIRYNNILHWDNWAKKIIEI"
BASE COUNT          267 a           91 c          146 g          234 t
ORIGIN      
        1 tttaaataaa aaaacaatta taaatgatga ggatgcaagt ttaatcgaac gcaaggctat
       61 tgaaaaagca acagtagtat ctttcccatc taaatgggca atggattttt gcaggaatta
      121 ttacagatta gattttgata aattagttga aataccatgg ggggctaatt tatttgatga
      181 tattcacttt gctaataaaa atataattca aaagaatagt tatacttgtc ttttcttggg
      241 agttgattgg gaaagaaaag gtgggaaaac agccttgaaa gcaattgaat atgtaaggca
      301 gttatatggg atcgatgtta gactaaaaat ttgtggatgt actccgaatc aaaagatttt
      361 acctacttgg gttgaattaa ttgataaagt agataaaaat aacgttgacg aatatcagaa
      421 attcatcgat gtgttatcta acgctgatat acttctttta ccaaccattg ctgaatgtta
      481 tggaatggta ttttgtgaag ctgctgcttt tggattgcct gttgtcgcta cagatacagg
      541 tggagtcagt tctatagtta tcaacgaaag gacggggata ttaattaaag acccgttaga
      601 ctataagcac tttggaaatg caattcataa aataattagt tccgtagaga cttatcaaaa
      661 ctactcccaa aacgcaagaa ttagatataa taatatattg cattgggaca attgggctaa
      721 aaagataatt gagattat
//
LOCUS       DAPOXO010000277          735 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.282, whole genome shotgun sequence.
ACCESSION   DAPOXO010000277 DAPOXO010000000
VERSION     DAPOXO010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.282"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>735
                     /locus_tag="ROH59_005220"
     rRNA            <1..>735
                     /locus_tag="ROH59_005220"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          207 a          156 c          229 g          143 t
ORIGIN      
        1 cataggttaa tgaggcgaac cgggggaact gaaacatcta agtaccccga ggaaaagaaa
       61 tcaaccgaga ttcccccagt agcggcgagc gaacggggag gagcccagag cctgaatcag
      121 tgtgtgtgtt agtggaagcg tctggaaagg cgcgcgatac agggtgacag ccccgtacac
      181 aaaaatgcac atattgtgag ctcgatgagt agggcgggac acgtggtatc ctgtctgaat
      241 atggggggac catcctccaa ggctaaatac tcctgactga ccgatagtga accagtaccg
      301 tgagggaaag gcgaaaagaa ccccggcgag gggagtgaaa aagaacctga aaccgtgtac
      361 gtacaagcag tgggagcctc ttaatggggt gactgcgtac cttttgtata atgggtcagc
      421 gacttatatt ctgtagcaag gttaaccgaa taggggagcc gaagggaaac cgagtcttaa
      481 ctgggcgtta agttgcaggg tatagacccg aaacccggtg atctagccat gggcaggttg
      541 aaggttgggt aacactaact ggaggaccga accgactaat gttgaaaaat tagcggatga
      601 cttgtggctg ggggtgaaag gccaatcaaa ccgggagata gctggttctc cccgaaagct
      661 atttaggtag cgcctcgtga attcatctcc gggggtagag cactgtttcg gcaagggggt
      721 catcccgact tacca
//
LOCUS       DAPOXO010000278          720 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.283, whole genome shotgun sequence.
ACCESSION   DAPOXO010000278 DAPOXO010000000
VERSION     DAPOXO010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.283"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>720
                     /locus_tag="ROH59_005221"
     CDS             <1..>720
                     /locus_tag="ROH59_005221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001305085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX4807566.1"
                     /translation="IHKEKVDLQHKNSPLKGNDNLIHKRINEYDNVLELSKNVSAQNS
                     GNEFSYLLGYADSLRKVGMLDTYIKIVCYLTIQSRYFKNGERVKLFEHISNALRYSRS
                     DFLINLIFERYIEYINHLKLSPKQKDFYFCTKFSKFHDYTKNGYKYLAFDNQADAGYG
                     LTLLLNANDDMQDSYNLLPEQELFICNAVIDNMNIYRSQFNKCLRKYDLSEITDIYPN
                     KIILQGIKFDKKKNVYGKDLVS"
BASE COUNT          273 a           92 c          109 g          246 t
ORIGIN      
        1 attcataagg agaaagttga tcttcaacat aaaaactcgc ctttaaaagg taacgataac
       61 cttattcaca aaagaataaa cgaatacgac aatgtacttg aactatctaa gaatgtatca
      121 gctcagaatt ctggcaatga gttttcttat ttattgggat atgcagattc tcttagaaaa
      181 gttggtatgt tggatactta tattaaaatt gtttgttatc taacaattca atctcgttat
      241 tttaaaaatg gcgaacgagt taagcttttt gaacatataa gtaacgctct acggtattca
      301 aggagtgatt ttctcattaa tcttattttt gaacgatata tcgaatatat aaaccatcta
      361 aaattgtcgc ccaaacaaaa agatttttat ttttgtacga agttttcaaa atttcatgat
      421 tatactaaaa atggatataa atatttagca tttgataatc aagccgatgc agggtatggc
      481 ctgactttat tattaaatgc aaacgatgat atgcaagata gttataatct actccctgag
      541 caagaacttt ttatttgtaa tgctgtaata gataatatga atatttatag gagtcaattt
      601 aacaaatgtc tacgaaaata cgatttatca gaaataactg atatataccc aaataaaatt
      661 atattgcaag gaattaagtt cgataagaaa aaaaatgttt atggaaaaga tcttgttagt
//
LOCUS       DAPOXO010000279          715 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.284, whole genome shotgun sequence.
ACCESSION   DAPOXO010000279 DAPOXO010000000
VERSION     DAPOXO010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..715
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.284"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(346..603)
                     /locus_tag="ROH59_005222"
     CDS             complement(346..603)
                     /locus_tag="ROH59_005222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807567.1"
                     /translation="MTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFP
                     LAKKGEGRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV"
BASE COUNT          195 a          167 c          174 g          179 t
ORIGIN      
        1 aatcaatttt gaactctgct taacggacat ttctgtataa cccttacggc aacgaaaaac
       61 gcgaagttaa aattttagaa acccaaaaac gtgacatgac taagtttaga tttcaggggg
      121 gagatcaaaa aatttcgctc tgtgccagag cggacattca cggagctggt tcattaccaa
      181 tgaggttggg cttttgagga taaatcaatg atcagacgcc aacgtaaatc aaaagcaacc
      241 ctggaacgga attgctaatc cagtttctga ccatcgattt ttctaaaaag tgtgcgtttg
      301 ctactactta ggtaggtgca gctttcttaa tcaccggcag ccacgttata caggccagtt
      361 gatggatcga ttgttatcaa tgatatcttc atgagtcggt gtctcaccca gcttaccgaa
      421 gctggcataa agtgaaggca gacgggcccg tccttctccc tttttcgcca gagggaaagc
      481 gcgaagcatg gtggcagcct cccagtcaca acaataggat ggtgtgcacg gctgctgacg
      541 ccatgattca gcgatagagc cggaaaatac ggggtcaaag ccggtatcat taaccagagt
      601 catcgtgacc tgtactgcgg ctggatgatc tcctgctact gcaactgcca ggcgaccgcg
      661 gctcccttca ggtagtctgt tgtggtcaac taaaactggc ctccgcgtta gagtt
//
LOCUS       DAPOXO010000280          694 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.285, whole genome shotgun sequence.
ACCESSION   DAPOXO010000280 DAPOXO010000000
VERSION     DAPOXO010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.285"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..683)
                     /locus_tag="ROH59_005223"
     CDS             complement(<1..683)
                     /locus_tag="ROH59_005223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004031776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HDX4807568.1"
                     /translation="MAIDRIIAQRNEGIALFMQAMECLATARKILLDASGDIFLYGFE
                     DCVTDSVRRMDKPEEAKRNITRLADRKIWDRLMTDTGMYTFMSSCQRDEWNSQLMSDT
                     CPEITLDNVLATFRHLNASKMQTFEQGLIDVYRKLSWDYRTNNPCRLGKKIIIENLLY
                     RWSNGRVTLDCSGREALDDLVRPFYLLEGRNVPDFRNSIGAQYGEFLGNGDNVGKLLE
                     GEYFTVRGY"
BASE COUNT          164 a          199 c          159 g          172 t
ORIGIN      
        1 tggtagccac gcaccgtaaa atattcccct tctaacagct taccgacatt gtcgccgttc
       61 ccgagaaatt caccatactg cgccccgatg ctgttcctga agtcaggaac gttgcgcccc
      121 tccagcagat aaaacggacg taccaggtca tccagtgcct cccgtccgct gcagtccagc
      181 gtcacacgcc cattactcca gcggtacagc aggttttcaa taatgatttt cttacccaga
      241 cggcagggat tattggttct gtaatcccat gacaatttcc ggtagacatc aatcagtccc
      301 tgttcaaacg tctgcatctt gctggcatta agatggcgga atgttgccag tacattgtcc
      361 agggtgattt caggacaggt gtcgctcatc agctggctgt tccactcatc acgctggcat
      421 gaactcatga aggtgtacat gcccgtatct gtcatcaggc ggtcccagat tttccggtcg
      481 gcaagacggg tgatattcct tttcgcttct tccggtttat ccatgcgacg aacggaatca
      541 gtcacgcagt cttcaaaccc gtaaagaaaa atatcacctg acgcatcgag cagaatcttg
      601 cgcgctgtcg ccaggcattc catcgcctgc atgaacagtg caataccttc gttacgctgc
      661 gcgatgatgc ggtcgatagc cacagacgga ataa
//
LOCUS       DAPOXO010000281          690 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.286, whole genome shotgun sequence.
ACCESSION   DAPOXO010000281 DAPOXO010000000
VERSION     DAPOXO010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.286"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>690
                     /locus_tag="ROH59_005224"
     CDS             <1..>690
                     /locus_tag="ROH59_005224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX4807569.1"
                     /translation="GRFKIIVRDNKSSMVLKKTCEKNCVTYLHGGQYGFGHNNNIAVS
                     YIINNFMIMNNDYFLFLNPDVFITSESLINYVDYIISNDYKFSTLCLYRDFTKSKHDY
                     SIRSFPTLYDFLCSFLLGVNKSKIKKENILSDTVVDWCAGSFMLIHALSFLNVNGFDQ
                     KYFMYCEDIDLCMRLKLSGVDLYYTPHFDAIHYAQHENRRIFTKAFRWHIRSITRYIL
                     RKPILSYKNYR"
BASE COUNT          240 a           80 c          112 g          258 t
ORIGIN      
        1 tggaagattt aaaataatag ttcgtgataa caaaagttca atggttttaa aaaaaacatg
       61 cgaaaaaaat tgcgtaacct atttgcatgg agggcaatat ggatttggac ataataataa
      121 catagcagtg tcatatataa ttaataactt catgattatg aataatgatt attttctctt
      181 tcttaacccc gatgtattca taaccagtga aagtttgatt aattatgttg attatataat
      241 tagtaatgat tataagttta gcacattatg tctttatcga gattttacta aaagcaaaca
      301 tgattattca atacggagtt ttccaacttt atatgatttt ctttgttctt ttttattggg
      361 ggtgaataaa agtaaaatta agaaggaaaa tatactttct gatactgtag ttgattggtg
      421 tgctggctca tttatgctta ttcatgcttt aagtttctta aatgtgaatg gttttgatca
      481 aaaatatttt atgtattgtg aagatattga cctttgtatg cgtttaaaat taagtggagt
      541 agatctttac tatactcccc attttgatgc tattcattat gcgcagcatg aaaatagaag
      601 aatatttact aaagcatttc gatggcatat aaggagtatt acgcgctaca tattacggaa
      661 accaattctt tcttataaaa actatagaaa
//
LOCUS       DAPOXO010000282          689 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.287, whole genome shotgun sequence.
ACCESSION   DAPOXO010000282 DAPOXO010000000
VERSION     DAPOXO010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.287"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>689
                     /locus_tag="ROH59_005225"
     CDS             <1..>689
                     /locus_tag="ROH59_005225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001305085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX4807570.1"
                     /translation="SLLNQTYENIEILVCDDCSSDKSLEIIKSIAYSDSRVKVYSSRK
                     NQGPYNIRNELIKKAHGNFITFQDADDLSHPERIQRQVEVLRNNKAVICMANWIRVAS
                     NGKIQFFYDDKATRMSVVSSMIKKDIFATVGGYRQSLIGADTEFYETVIMRYGRESIV
                     RLLQPLILGLWGDSGLTRNKGTEALPDGYISQSRREYSDIAARQRVLGKSIVSDKDVR
                     GLLSRYGLFKDV"
BASE COUNT          241 a           99 c          150 g          199 t
ORIGIN      
        1 tcattgttga atcaaacata tgaaaatatt gaaattctcg tgtgcgatga ttgttcatcg
       61 gacaaaagcc ttgaaataat taagagcata gcttattctg attcaagagt gaaagtatat
      121 agctcacgaa aaaaccaagg cccttataat ataagaaatg agctaataaa aaaagcacac
      181 ggtaatttca tcacctttca agatgcagat gatctttctc atccggagag aatacaaaga
      241 caagttgagg ttcttcgcaa taataaggct gtaatctgta tggctaactg gatccgtgtt
      301 gcgtcaaatg gaaaaattca attcttctat gatgataaag ccacaagaat gtctgttgta
      361 tcgtcaatga taaaaaaaga tatttttgcg acagttggtg gctatagaca atctttaatt
      421 ggtgcagata cggagtttta tgaaacagta ataatgcgtt atgggcgaga aagtattgta
      481 agattactgc agccattgat attggggtta tggggagact ccggacttac caggaataaa
      541 ggaacagaag ctctacctga tggatatata tcacaatctc gaagagaata tagtgatatc
      601 gcggcaagac aacgagtgtt agggaaaagt atcgtaagtg ataaagatgt acgtggttta
      661 ttatctcgct atggtttgtt taaagatgt
//
LOCUS       DAPOXO010000283          672 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.288, whole genome shotgun sequence.
ACCESSION   DAPOXO010000283 DAPOXO010000000
VERSION     DAPOXO010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.288"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>672
                     /locus_tag="ROH59_005226"
     CDS             <1..>672
                     /locus_tag="ROH59_005226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807571.1"
                     /translation="ESLCLQSEKGGKTSYKDITKIQLATTEKQKLLASLEVVNSMSSY
                     VELLTVGMDVEDSKQIILLNQALDHANNAQKLLGLSEGEELTKSVVAVKDLVQYFNGL
                     YKEKIKSENVGKTVGSDWPRLQRNLQDLLDDIATKQQQMDRNNYANISNNFYYYNKAQ
                     ANTKNIEFKTLKSRQEFLSAVINLNESRLRSSDPAAPAIQAINAFMDKGNHLQDLYSN
                     KSLSKA"
BASE COUNT          249 a          106 c          135 g          182 t
ORIGIN      
        1 gagtccttat gtttgcaatc agagaaaggg ggcaaaacat cgtataaaga cattactaaa
       61 attcaattgg caacaacaga aaaacaaaaa ctactggctt cacttgaggt cgttaacagt
      121 atgagttcct atgtggagtt gttgacggtg ggtatggatg ttgaggatag taaacaaatt
      181 atattactta atcaggcgct cgatcacgca aacaacgccc aaaaactact tggcctttca
      241 gaaggtgaag aattgactaa gtcagttgtg gctgttaaag atttagttca atatttcaat
      301 ggattataca aagagaagat taaatcagaa aatgttggta aaacggtagg tagtgactgg
      361 cctcgacttc aaagaaattt acaagattta ctcgatgata tagcaacgaa acagcagcaa
      421 atggatcgga ataattatgc gaacatcagt aataattttt attactacaa taaggcccag
      481 gcaaatacta aaaatataga gtttaagaca ttaaagagca ggcaggaatt tttgagtgca
      541 gtaattaatc ttaatgaaag cagattgcgt tcatctgatc cggcggctcc agcaatacaa
      601 gctattaatg ccttcatgga taaaggaaat catctacaag atttatactc taataaatct
      661 ctttcaaaag cg
//
LOCUS       DAPOXO010000284          660 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.289, whole genome shotgun sequence.
ACCESSION   DAPOXO010000284 DAPOXO010000000
VERSION     DAPOXO010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..660
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.289"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(239..574)
                     /locus_tag="ROH59_005227"
     CDS             complement(239..574)
                     /locus_tag="ROH59_005227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4432 domain-containing protein"
                     /protein_id="HDX4807572.1"
                     /translation="MQGEASLSTLNQPEFYDPEIVFFADKLDAYTDLPEFRMIAPDGT
                     TFVTRFSSAELNYVTRWILYNGEQQVAAFALPATCRPEGYLAAQRNGTLIQVAPQQTR
                     TFTVTTGIE"
BASE COUNT          181 a          142 c          168 g          169 t
ORIGIN      
        1 tttttgttga ccactacaaa taaataaaag agttgcagtg cttgctcggt aagaaaacaa
       61 tggaagttga gatcctaaaa gaagctgtgg agtacaccac tctacagtag ttgcgcaaat
      121 ttggagtgga cgataatgtg atcgtctata agggcaacgc tatcatagtc ttgtcctggc
      181 gggtaaaaaa acgcgcttac cttaacgata agcgcgccgc tgttcaggcc ttaagtggtt
      241 attcaattcc tgtggtgact gtaaaagtgc gtgtttgctg cggtgcaacc tgaatcagcg
      301 tgccattacg ttgcgcggca agatacccct caggccgaca ggttgcaggt aatgcaaagg
      361 cggctacctg ttgctcgccg ttataaagga tccagcgtgt cacataattt agttcggcac
      421 tggagaaacg agtaacaaac gtagtgccat cgggagcgat catgcgaaac tctggcagat
      481 ctgtgtaagc gtccagtttg tctgcaaaga agactatttc tggatcataa aattccggtt
      541 gattcagcgt cgacagagag gcttctccct gcataatccg ttgattaaac gccagccact
      601 gagcggtggg attaacatgc gaaggtactg attcacgcaa ccttaatatt tcgtccggta
//
LOCUS       DAPOXO010000285          626 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.290, whole genome shotgun sequence.
ACCESSION   DAPOXO010000285 DAPOXO010000000
VERSION     DAPOXO010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..626
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.290"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(251..>626)
                     /locus_tag="ROH59_005228"
     CDS             complement(251..>626)
                     /locus_tag="ROH59_005228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HDX4807573.1"
                     /translation="WAGFESYPVGSPIPWPSATPPQGYLVMNGQSFSCSRYPQLARAY
                     PGCKLPDLRGVFIRGWDNGRGLDGDRNRHLLSYQADQSGVYHERGGWLKGHHSGMPYW
                     AQGSTTEMRPKNIAFNYIVKAS"
BASE COUNT          155 a          153 c          173 g          145 t
ORIGIN      
        1 tctggaagaa taatatcagc gatgcactgg tttttgatta ttcggcctgt tatgacgcag
       61 aagaagactc cagaaaaccg gtttatgcga actggggtag tggctcaaac ggctttgccg
      121 tctgtgacgg caaagccggc tatggtgcgg caggattcag agcgtacaga ggtaaaccgg
      181 ggtattcggg aagcatggtc tgggtcaaaa tacgttgctg taagttaaaa gttaatacgc
      241 cttaaatgca tcagcttgct ttgacgatgt agttaaaggc aatgtttttg gggcgcattt
      301 ccgttgtgct tccctgggcc cagtaaggca taccgctgtg atgccctttc agccatcccc
      361 cacgctcatg atagacaccg gattgatcgg cctgataact caggagatgt ctgttccgat
      421 ctccatccag cccacgtccg ttgtcccagc cacggataaa aacaccgcgc aaatccggca
      481 gcttacaccc gggataagca cgggcaagct gaggataccg ggaacatgaa aatgactgcc
      541 cgttcatcac caggtagcct tgtggagggg tggctgatgg ccacggtata gggcttccga
      601 cagggtagga ttcaaaacct gcccac
//
LOCUS       DAPOXO010000286          620 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.291, whole genome shotgun sequence.
ACCESSION   DAPOXO010000286 DAPOXO010000000
VERSION     DAPOXO010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.291"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>620
                     /locus_tag="ROH59_005229"
     CDS             <1..>620
                     /locus_tag="ROH59_005229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HDX4807574.1"
                     /translation="IPSVAIDRIIAQRNEGIALFMQAMECLATARRILLDASGDIFLY
                     GFEDCVTDSVRCMDKPEEAKKNITRLADRKIWDRLMTDTGMYTFMSSCQRDEWNSQLM
                     SDTCPEITLDNVLATFRHLNASKMQTFEQGLIDVYRKLSWDYRTNNPCHLGKRIIIEN
                     LLYRWSNGRVTLDCSGREALDDLVRPFYLLEGRNVPDFRSSIGAQY"
BASE COUNT          154 a          150 c          172 g          144 t
ORIGIN      
        1 ttattccgtc tgtggccatc gaccgcatta tcgcgcagcg taacgaaggt attgcactgt
       61 tcatgcaggc gatggaatgc ctggcgacag cgcgcaggat tctgctcgat gcttctggtg
      121 acatttttct ctacgggttt gaagactgcg tgactgactc cgttcgatgc atggataaac
      181 cggaagaagc aaaaaagaat atcacccgtc ttgccgaccg gaaaatctgg gatcgcctga
      241 tgacagatac gggcatgtac accttcatga gttcatgcca gcgtgatgag tggaacagcc
      301 agctgatgag cgacacctgt cctgaaatca ccctggacaa tgtactggca acattccgcc
      361 atctgaatgc cagcaagatg cagacatttg aacagggact gattgatgtc taccggaaat
      421 tgtcatggga ttacagaacc aataatccct gtcatcttgg caagagaatc attattgaaa
      481 acctgctgta ccgctggagt aacgggcgtg tgacgctgga ctgcagcgga cgggaggcac
      541 tggatgacct ggtacgtcct ttttatctgc tggaggggcg caacgttccg gacttccgga
      601 gcagcatcgg ggcgcagtat
//
LOCUS       DAPOXO010000287          610 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.292, whole genome shotgun sequence.
ACCESSION   DAPOXO010000287 DAPOXO010000000
VERSION     DAPOXO010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.292"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            157..>610
                     /locus_tag="ROH59_005230"
     CDS             157..>610
                     /locus_tag="ROH59_005230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807575.1"
                     /translation="MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMS
                     IGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
                     ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGL"
BASE COUNT          148 a          123 c          160 g          179 t
ORIGIN      
        1 ttgctattta aaagtcttga ttgtgaagat tttctctgat ctcacgcgta tcatttcttt
       61 attctaataa ctcgcctgca aaaacgtaga ccgcatatcg ccttgatgcg gctcggaaaa
      121 aaataataag ccctacaaaa tattgagcga gaaattatgg aaattgcatc gaataaaggc
      181 gtcattgcag acgcttcgac cccggcgggt cgtgctggaa tgagtgagag cgagtggcga
      241 gaagcgatca aattcgacag tactgacact ggctgggtga ttatgagtat cgggatggcg
      301 attggcgcgg ggattgtttt tctcccggtg caggtcggtt tgatgggatt gtgggtattt
      361 ttgctctcat cggtgattgg ttacccggca atgtatctgt ttcagcggtt gtttattaat
      421 acgctggcag aatcaccaga atgtaaagat tacccgagcg tcatcagcgg ttatttaggt
      481 aaaaactggg gcatcctgtt aggtgcactc tatttcgtaa tgctggtgat ttggatgttc
      541 gtctattcca ccgccatcac caacgatagt gcttcctacc tgcatacctt cggcgtgacg
      601 gaagggttgc
//
LOCUS       DAPOXO010000288          597 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.293, whole genome shotgun sequence.
ACCESSION   DAPOXO010000288 DAPOXO010000000
VERSION     DAPOXO010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.293"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>597
                     /locus_tag="ROH59_005231"
     CDS             <1..>597
                     /locus_tag="ROH59_005231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase"
                     /protein_id="HDX4807576.1"
                     /translation="GYCNSLCYHGKLQPKRGMEKGTIFPAMGYLHIDGRGMKPNGGSR
                     YNPLEAETIAAWLVAHKDDIERHYGEPLYKVVGVVTPFSAQVNAIKTSLRKLEINGKD
                     EQGSLTVGTVHSLQGAERAIVLFSPVYSKHEDGRFLDSNSSILNVAVSRAKDSFLVFG
                     DMDLIEMQPAFSPRGLLAKYLFSSDNNALQFEFQKRQDL"
BASE COUNT          164 a          115 c          156 g          162 t
ORIGIN      
        1 ggctactgta actcactttg ctatcacggt aagttgcagc ctaaaagagg gatggaaaaa
       61 gggacgattt tccccgcaat gggatattta catattgatg gtagaggcat gaagccaaat
      121 ggaggaagcc gttataaccc tcttgaagct gaaacaatag cagcatggct ggtggcacat
      181 aaggatgata tagagcgcca ttacggggaa ccactgtaca aagttgttgg tgttgtgacg
      241 ccattttcgg cgcaggttaa tgctatcaaa acgtcattgc gtaagctgga aattaatggc
      301 aaagacgagc agggttcact gacagtgggg actgtgcact ccttgcaggg ggcggaaagg
      361 gcgattgttc tcttttctcc tgtctactca aaacatgaag atggcaggtt tcttgatagc
      421 aacagcagta tcctcaatgt tgctgtctca cgcgctaaag atagttttct ggtatttggc
      481 gatatggacc ttatcgagat gcagcccgca ttttcgccgc gagggttatt ggcaaaatat
      541 ctcttttctt cagataataa tgcgttgcaa tttgagtttc agaaacgaca ggattta
//
LOCUS       DAPOXO010000289          593 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.294, whole genome shotgun sequence.
ACCESSION   DAPOXO010000289 DAPOXO010000000
VERSION     DAPOXO010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.294"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            30..467
                     /gene="umuD"
                     /locus_tag="ROH59_005232"
     CDS             30..467
                     /gene="umuD"
                     /locus_tag="ROH59_005232"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HDX4807577.1"
                     /translation="MSTVYHRPADPSGDDSYVRPLFADRCQAGFPSPATDYAEQELDL
                     NSYCISRPAATFFLRASGESMNQAGVQNGDLLVVDRAEKPQHGDIVIAEIDGEFTVKR
                     LLLRPRPALEPVSDSPEFRTLYPENICIFGVVTHVIHRTRELR"
     gene            467..>593
                     /locus_tag="ROH59_005233"
     CDS             467..>593
                     /locus_tag="ROH59_005233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807578.1"
                     /translation="MFALADINSFYASCEKVFRPDLRNEPVIVLSNNDGCVIARSP"
BASE COUNT          126 a          166 c          165 g          136 t
ORIGIN      
        1 tggcaggacg acagctggct gcctgcagca tgagtaccgt ttatcaccgt ccggctgacc
       61 cttcaggcga tgacagttac gtgcgaccgt tgtttgccga tcgttgccag gccggttttc
      121 cttcgcctgc cactgattat gctgagcagg aactggatct gaacagctat tgcatcagca
      181 gacctgcagc caccttcttt ctgcgcgcca gcggtgaatc gatgaaccag gctggcgtgc
      241 agaatggtga tctgctggta gtggacaggg ccgaaaaacc acaacacggg gacatcgtta
      301 tcgctgagat cgacggtgag ttcaccgtca aacgactgct gttgcgccca cgcccggcac
      361 tggagccggt ttcagacagc ccggagttcc gcacactgta tccggaaaac atctgtattt
      421 ttggtgttgt cactcacgtg atacacagga cgcgggagtt acgctgatgt ttgcactggc
      481 tgatatcaac agtttctacg cctcatgtga aaaagttttc cgcccggacc ttcgcaacga
      541 accggtcatc gtactcagca ataacgatgg ctgtgtgatc gcgcgcagcc cgg
//
LOCUS       DAPOXO010000290          587 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.295, whole genome shotgun sequence.
ACCESSION   DAPOXO010000290 DAPOXO010000000
VERSION     DAPOXO010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.295"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(321..>587)
                     /locus_tag="ROH59_005234"
     CDS             complement(321..>587)
                     /locus_tag="ROH59_005234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HDX4807579.1"
                     /translation="NRDTWCRAGDYRAPGSLAGMIKQAWCSALGVDVGCHATLVHFPA
                     WPAVWLERDDDTGFQQVLERADYLAKEHTKAHCTGERNFGCSRS"
BASE COUNT          135 a          172 c          161 g          119 t
ORIGIN      
        1 cagtacgggc gcccgtcaga cgtccgttgc catcaagagc gataaaggat tttgcgtaca
       61 tagtcatatt cctcagccgc cagacgacac gcaggcaaca gccgtcccgg tacgggcagc
      121 gtggtcaggg tgtgaatggc ggttcagtta aaatctggac tggagtttgg gtaaagcagg
      181 ctggttgctg ttacagcact gtggttgtca cacaatggaa cactgacgta aaaaacagtc
      241 agtgggcgag tggatacatc gttgccgcca gacaacaacc catacttttg gtttgccggg
      301 tattggcgcg ccagtcgtgc tcaactccgg ctacagccaa aattgcgctc accggtgcag
      361 tgagctttgg tatgttcctt cgccagatag tcagcacgtt ccagcacctg ctgaaagcca
      421 gtgtcatcat cgcgttccag ccacaccgcc ggccaggccg gaaaatgcac cagcgtggca
      481 tggcacccga catccactcc cagggcactg caccacgcct gtttaatcat cccggccagt
      541 gatcccggag cacggtaatc accggcacga caccaggtat cccggtt
//
LOCUS       DAPOXO010000291          568 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.296, whole genome shotgun sequence.
ACCESSION   DAPOXO010000291 DAPOXO010000000
VERSION     DAPOXO010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.296"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT          166 a          110 c          115 g          177 t
ORIGIN      
        1 catgggtaaa taattcgtta ttatttgagt aattctctaa atatgtagat aatggcgagt
       61 taacgtatca cctgacacac ttctctccga aattaagaag tatttgactc atcaagccaa
      121 taaatgtgta tagaatgatt atacgggata gttacaagtt caccgatacg gtgcaggact
      181 caatggcgat gtcggtggga gcgtttgtgt cacgatatga tggacgtccc ttcttaatgc
      241 agtcagtgcc atacttttac tgactgcatt aatccgagag taacatccca tgaacacgat
      301 caggattgtt ggtatcgata ttgccaggcc tgtttttcag gcctatatct ggattaatga
      361 tgattctgtt gcataggata gaaacacctc atgctccaaa ttgcaggata tcgttcaacg
      421 attcgagtcc ggaacactat tcgctatgga ggcatgttca acttctcatt ctgggggatg
      481 aacgttcagt tctatggaat atcccctgac tattccctgc acaacagcat catttttggt
      541 aaaaaaaata acattattct taatatat
//
LOCUS       DAPOXO010000292          565 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.297, whole genome shotgun sequence.
ACCESSION   DAPOXO010000292 DAPOXO010000000
VERSION     DAPOXO010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.297"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            494..>565
                     /locus_tag="ROH59_005235"
     CDS             494..>565
                     /locus_tag="ROH59_005235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDX4807580.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVH"
BASE COUNT          150 a          158 c          127 g          130 t
ORIGIN      
        1 taccattttg cagggagccg gtgcgttact gtctggcaca acaaacgcag cgggtcgctc
       61 tgccccgccg attcctgata atccctcccc tgtaacctac tgcaacagta caaatacact
      121 gacgcctgaa acggtaacca gaatcagcac cagcagtaac gtcagtaaac agagcagacg
      181 atcggtcttc cggtaataac cgaaggggtc gacagcgcca caatacgggc aacaaactgt
      241 attatgagta attgcgttac cacagtccct gcacttcttt ttgcgtatca cgatagctcc
      301 ctcgccacgc cttatccgta accggttttt tacattaaaa aaaacaacgc cgggaattca
      361 atcgtcagtc cggagacgac cgttcgggtt atcacagagt gcctgagaca gtgtcctgcc
      421 ggaggtcact tcagggactc tgcgtatttt ttacgacgtg gctattccgt atgaaccata
      481 cggagattta accatgacct acaaatacaa ccccttctgg cagcaacgta ttcgtgagac
      541 ggtgcggcac gcactgaatg ttcat
//
LOCUS       DAPOXO010000293          564 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.298, whole genome shotgun sequence.
ACCESSION   DAPOXO010000293 DAPOXO010000000
VERSION     DAPOXO010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..564
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.298"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            493..>564
                     /locus_tag="ROH59_005236"
     CDS             493..>564
                     /locus_tag="ROH59_005236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDX4807581.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVH"
BASE COUNT          145 a          159 c          126 g          134 t
ORIGIN      
        1 taccattttg cagggagccg gtgcgttact gtctggcaca acaaacgcag cgggtcgctc
       61 tgccccgccg attcctgata atccctcctc tgtaacctac tgcaacagta caaatacact
      121 gacgcctgaa acggtaacca gaatcagcac cagcagtaac gtcagtaaac agagcagacg
      181 atcggtcttc cggtaataac cgaaggggtc gacagcgcca caatacgggc aacatactgt
      241 attatgagta attgcgttac cacagtccct gcacttcttt ttgcgtatca cgatcgctcc
      301 ctctccacgc cttatccgta acctgttttt tacattaaaa aaacaacgcc gggaattcaa
      361 tcgtcagtcc ggcgatgacc gttcgggtta tcacagagtg cctgagacag tgtcctgccg
      421 gaggtcacct caggggctct gcgcattttt tacgacgtgg ttattccgta tgaaccatac
      481 ggagatttaa ccatgaccta caaatacaac cccttctggc agcaacgtat tcgtgagacg
      541 gtgcggcacg cactgaatgt tcat
//
LOCUS       DAPOXO010000294          553 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.299, whole genome shotgun sequence.
ACCESSION   DAPOXO010000294 DAPOXO010000000
VERSION     DAPOXO010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.299"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..>553)
                     /locus_tag="ROH59_005237"
     CDS             complement(<1..>553)
                     /locus_tag="ROH59_005237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein ImpB"
                     /protein_id="HDX4807582.1"
                     /translation="MGQPWFQVRQMRLEKKIHVFSSNYALYHSMSQRVMAVLESLSPA
                     VEPYSIDEMFIDLRGINHCISPEFFGHQLREQVKSWTGLTMGVGIAPTKTLAKSAQWA
                     TKQWPQFSGVVALTAENRNRILKLLGLQPVGEVWGVGRRLTEKLNALGINTALQLAQA
                     NTAFIRKNFSVILERTVRELNGES"
BASE COUNT          123 a          161 c          126 g          143 t
ORIGIN      
        1 ggactcgccg ttgagttcgc gtaccgtacg ctcaagaatg acgctgaagt ttttccggat
       61 gaatgccgtg ttagcctgcg ccagctgcag tgctgtgtta atacccagcg cattcagctt
      121 ttccgtcagt ctgcgtccta ctccccagac ctcaccaact ggctgcagcc ccagtagctt
      181 caagatccga ttacggtttt ctgccgtcag cgcgaccaca ccggaaaact gtggccattg
      241 ctttgttgcc cactgtgcac ttttagccag cgtttttgta ggcgcaatgc ccacccccat
      301 ggtgagtcct gtccagcttt ttacctgttc cctgagctga tgaccaaaaa actccggaga
      361 gatgcaatga tttatccccc gcaaatcaat gaacatttca tcaattgagt agggctcaac
      421 tgcgggagaa agcgactcca gaacagccat aacccgttgg ctcatgctgt ggtacagcgc
      481 ataattgctg gaaaatacat gtattttctt ctccaggcgc atttgtctca cctgaaacca
      541 gggctgcccc att
//
LOCUS       DAPOXO010000295          553 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.300, whole genome shotgun sequence.
ACCESSION   DAPOXO010000295 DAPOXO010000000
VERSION     DAPOXO010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.300"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..>553)
                     /locus_tag="ROH59_005238"
     CDS             complement(<1..>553)
                     /locus_tag="ROH59_005238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein ImpB"
                     /protein_id="HDX4807583.1"
                     /translation="MGQPWFQVRQMRLEKKIHVFSSNYALYHSMSQRVMAVLESLSPA
                     VEPYSIDEMFIDLRGINHCISPDFFGHQLREQVKSWTGLTMGVGIAPTKTLAKSAQWA
                     TKQWPQFSGVVALTAENRNRTLKLLGLQPVGEVWGVGRRLTEKLNALGINTALQLAQA
                     NTAFIRKNFSVILERTVRELNGES"
BASE COUNT          122 a          162 c          127 g          142 t
ORIGIN      
        1 ggactcgccg ttgagttcgc gtaccgtacg ctcaagaatg acgctgaagt ttttccggat
       61 gaatgccgtg ttagcctgcg ccagctgcag tgctgtgtta atacccagcg cattcagctt
      121 ttccgtcagt ctgcgtccta ctccccagac ctcaccaact ggctgcagcc ccagtagctt
      181 caaggtccga ttacggtttt ctgccgtcag cgcgaccact ccggaaaact gtggccattg
      241 ctttgttgcc cactgtgcac ttttagccag cgtttttgta ggcgcaatgc ccacccccat
      301 ggtgagtcct gtccagctct ttacctgttc cctgagctga tgaccaaaaa aatccggaga
      361 gatgcaatga tttatccccc gcaaatcaat aaacatttca tcaattgagt agggctcaac
      421 tgcgggagaa agcgactcca gaacagccat gacccgttgg ctcatgctgt ggtacagcgc
      481 ataattgctg gaaaatacat gtattttctt ctccaggcgc atctgtctca cctgaaacca
      541 gggctgcccc att
//
LOCUS       DAPOXO010000296          533 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.301, whole genome shotgun sequence.
ACCESSION   DAPOXO010000296 DAPOXO010000000
VERSION     DAPOXO010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.301"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            86..334
                     /locus_tag="ROH59_005239"
     CDS             86..334
                     /locus_tag="ROH59_005239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001349157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807584.1"
                     /translation="MFIYASGGNGGSAGGACANTSRLQGYVGGTLISVNASNNPAYGK
                     TAFISFAVPAGTSYQITSYPTENTSCGAGVFSVFGYQT"
     gene            complement(331..>533)
                     /locus_tag="ROH59_005240"
     CDS             complement(331..>533)
                     /locus_tag="ROH59_005240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012565250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807585.1"
                     /translation="TIGGKLKVTQLSTTGYLGQFDFCAIARMGNAEDAHYCQVVESPA
                     GSRKWYKYEHKTGCIASCVTLN"
BASE COUNT          135 a          119 c          126 g          153 t
ORIGIN      
        1 gacttctggt tcgctcaatg gttcttacac aaacttaggt tcacatagag gttcattctc
       61 agggcggaat tcagggggca gtacattgtt tatttatgca tctggaggta atggaggatc
      121 tgccggaggt gcatgtgcaa atacatcccg actgcaggga tatgttggtg ggacgctaat
      181 tagcgtgaat gccagcaata accctgcata tggaaaaaca gcctttatca gctttgctgt
      241 acctgcaggt acttcctatc agataacatc ctatccaaca gaaaatacat catgtggtgc
      301 cggggtattt tcagtatttg gatatcaaac ttaattgagc gttacacacg acgcaataca
      361 acctgtctta tgctcgtatt tgtaccattt gcgtgaacct gctgggctct caactacctg
      421 gcagtagtgg gcatcctctg cgttgcccat tctggcaatg gcacagaagt cgaattgccc
      481 cagataacct gtggtggaaa gctgagtaac tttgagtttt ccacctattg tcc
//
LOCUS       DAPOXO010000297          517 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.302, whole genome shotgun sequence.
ACCESSION   DAPOXO010000297 DAPOXO010000000
VERSION     DAPOXO010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.302"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..374)
                     /locus_tag="ROH59_005241"
     CDS             complement(<1..374)
                     /locus_tag="ROH59_005241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDX4807586.1"
                     /translation="MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIG"
BASE COUNT          154 a          107 c          108 g          148 t
ORIGIN      
        1 ccaatggtgt tggtgccaac ggcctgacca tttttcggtg caggcgcatg ccacagatcg
       61 gcaaccatgt ttacgcaacg caggtcgatt gctgcagatt gcggatattc ttctttgtcg
      121 atccagtttt tattgatcga caaatccatc aatttatgga cgttttcgtc gtcccaggtc
      181 tggcagaaag tggccaggtt ctgacgagcg ttgccatcaa gatataattc atcattgata
      241 atctgaaatg caacatcatc gcgcatttcg tgcagcggaa atcgttttga ctccgcgata
      301 gtagaaatgg cctttgcacc aaaacgtgaa tcgagtagtt ctgagcggaa atccgttaac
      361 agcttctggt ccatttcgaa ctccttaaat ttatttgaag gcaataaaaa agtaggattt
      421 atccgcaatg gaagcaaggc attacaggct taatttaaat aacaaaatcc taagcagaaa
      481 aacgaccttt tataatataa acatttaata tgataat
//
LOCUS       DAPOXO010000298          517 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.303, whole genome shotgun sequence.
ACCESSION   DAPOXO010000298 DAPOXO010000000
VERSION     DAPOXO010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.303"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            52..517
                     /locus_tag="ROH59_005242"
                     /pseudo
     CDS             52..517
                     /locus_tag="ROH59_005242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEc52 family transposase"
BASE COUNT          161 a          131 c          124 g          101 t
ORIGIN      
        1 gccacctgaa cagaggtgat atgctcacct cagaacaaca caggtgccat aatgaaaaaa
       61 agaaatttca gcgcagagtt taaacgcgaa tccgctcaac tggtcgttga ccagaattac
      121 accgtggcag atgcagccag cgctatggat gtcggccttt ccacaatgac gcgatgggtg
      181 aaacaattac gtgatgagcg gcagggaaaa acaccaaaag cctcccctat taccccggaa
      241 caaattgaaa tccgtgagct caggaaaaag ctacaacgta ttgaaatgga aaatgaaata
      301 ttaaaaaagg ctaccgcgct cttgatgtca gactccctga acagttctcg ataatcggga
      361 aactcagggc gcgttatcct gtggccactc tctgccatgt gttcggggtc catcgcagca
      421 gctacaaata ctggaaaaac cgtcctgaaa agccagacgg cagacgggct gtattacgca
      481 gccaggtact tgaactgcat ggcatcagcc acggctc
//
LOCUS       DAPOXO010000299          509 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.304, whole genome shotgun sequence.
ACCESSION   DAPOXO010000299 DAPOXO010000000
VERSION     DAPOXO010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.304"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..413)
                     /locus_tag="ROH59_005243"
     CDS             complement(<1..413)
                     /locus_tag="ROH59_005243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2931 family protein"
                     /protein_id="HDX4807587.1"
                     /translation="MKIIAKIIYRLTIALMIAGSVQTAAKEKISLLAPYDEWYFNFFY
                     PNSLPAQVTYVELLDTDGIYYQFRTLDSTIPVSTTIGQWQENLSGGMTAFNKAKNPPM
                     SIHFCWDSVIDKKEYETWITLAGDVWKLMLTPYSPP"
BASE COUNT          145 a           95 c           99 g          170 t
ORIGIN      
        1 ggtggtgaat aaggtgtgag catcaatttc cagacgtctc ccgccagcgt tatccaggtt
       61 tcatactctt ttttatcaat cactgaatcc cagcagaaat ggatagacat agggggattt
      121 ttggctttat tgaatgccgt cattccacca ctaagatttt cctgccattg tcctattgtt
      181 gttgagacag ggatagtgct atccagagtt ctgaactgat aatagatgcc atcggtatct
      241 aataattcca cataggtaac ttgtgctggt agggaattag ggtaaaaaaa attgaaatac
      301 cattcatcat agggtgcaag cagtgatatt ttttctttcg ctgctgtctg gactgatccg
      361 gctatcatta acgcaatggt taatctataa attattttag ctattatttt cattgttact
      421 taccagttac catagggata ttttttatct ttgataaact caagaacata ttcatcgtct
      481 ccaagagaaa aatcatgccg ggaaattcc
//
LOCUS       DAPOXO010000300          508 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.305, whole genome shotgun sequence.
ACCESSION   DAPOXO010000300 DAPOXO010000000
VERSION     DAPOXO010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.305"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            248..>508
                     /locus_tag="ROH59_005244"
     CDS             248..>508
                     /locus_tag="ROH59_005244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016158921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDX4807588.1"
                     /translation="MNSQNALSNMRLAVRGDISGNSTLVLKKIRFYNCAIIYLRNAQL
                     LVKTIDGGVINIPPESICYIEKNTVIDVTLNVLGKGMPYDIFH"
BASE COUNT          156 a           73 c           95 g          184 t
ORIGIN      
        1 acacggaagc ttccaattct ttttaggtgt tatctgtaac atcaactgat tttattttca
       61 tgacgtaact attatcagag tcaattaatt ttatcatcat agtgactaat tatttatagt
      121 ctatgaaatt agttgatatg tcgatgcgaa actttttacc gggaagtatt catctttgcg
      181 ttatttccga gtttacagag tggatatccc atgaaattat gttgttacaa agcatggggg
      241 tgactgtatg aatagtcaaa atgctttaag taatatgagg cttgctgtga gaggggatat
      301 atccggtaac tctacattgg ttcttaaaaa gattagattc tacaattgtg ccattattta
      361 tcttcgcaat gcccaattac ttgttaaaac gatagatggg ggggttatta atatcccacc
      421 tgaatcaata tgttatattg agaaaaatac agtcattgat gtaacactta acgtgttagg
      481 taaaggcatg ccttatgata tttttcat
//
LOCUS       DAPOXO010000301          504 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.306, whole genome shotgun sequence.
ACCESSION   DAPOXO010000301 DAPOXO010000000
VERSION     DAPOXO010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.306"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..195)
                     /locus_tag="ROH59_005245"
     CDS             complement(<1..195)
                     /locus_tag="ROH59_005245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kfiB protein"
                     /protein_id="HDX4807589.1"
                     /translation="MNKLVLVGHPGSKYQIVEHFLKEIGMNSPNYSTSNKISPEYITA
                     SLCQFYQTPEVNDVVDEREFS"
BASE COUNT          167 a           86 c           64 g          187 t
ORIGIN      
        1 tgagaattct ctctcatcta ctacatcatt aacttctggt gtttgataaa attgacataa
       61 tgaagcggtg atatattctg gggaaatttt attacttgta gaataatttg gtgagttcat
      121 gccaatttct ttcaaaaaat gttcaactat ctgatacttt gagccaggat gtccgactag
      181 cactaattta ttcatcatat ttcctcttta ttatctacaa gattacttta ttttaaacac
      241 tgtcgtttat cgtaatggtg atattgcaga catatatttc aaatctgtaa tgtaatttag
      301 gtggcgttat gtgataatac taaatgaaac tatctatatc tcaatagcac atctgattta
      361 tttggtatag ccattcatca ataaacaata tcaatataac tcagagcacc tcctaataat
      421 tgacatattg cgttaccacc ttcttttaga caaaaatctt aattataaac tctaccaaac
      481 taacgctgat atttttcaaa atca
//
LOCUS       DAPOXO010000302          499 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.307, whole genome shotgun sequence.
ACCESSION   DAPOXO010000302 DAPOXO010000000
VERSION     DAPOXO010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.307"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>499
                     /locus_tag="ROH59_005246"
     CDS             <1..>499
                     /locus_tag="ROH59_005246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS600 family transposase"
                     /protein_id="HDX4807590.1"
                     /translation="KYALIEQWRQQFPIEAMCQVFGVSRSGYYNWVQHEPSDRKQSDE
                     RLKLEIKVAHIRTRETYGTRRLQTELAENGIIVGRDRLARLRKELRLRCKQKRKFRAT
                     TNSNHNLPVAPNLLNQTFAPTAPNQVWVADLTYVATQEGWLYLAGIKDVYTCEIVGYA
                     MGERMT"
BASE COUNT          143 a          119 c          136 g          101 t
ORIGIN      
        1 aaaatacgcg ttaatcgaac aatggcgaca acaatttccc attgaagcga tgtgtcaggt
       61 atttggtgta tccaggagcg gttattacaa ctgggtacag catgaaccct cagacagaaa
      121 acaaagtgat gagcggctaa aactggagat taaggtggca catatccgca ctcgcgaaac
      181 atatggaacc cggcggctcc agacggagct ggcagagaat ggcatcatcg ttggtcgtga
      241 ccgactggca cgtcttcgta aggagctaag gctacgctgt aagcagaaac gcaagttcag
      301 agcgactacg aactcgaacc acaatctgcc agttgcgcca aatctgctga accagacgtt
      361 cgctcctaca gcaccaaatc aggtctgggt ggcggacctg acgtatgttg ccacacagga
      421 gggatggttg tacctcgctg gcatcaaaga tgtttatacg tgcgaaattg tcggctacgc
      481 catgggagag cgcatgaca
//
LOCUS       DAPOXO010000303          486 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.308, whole genome shotgun sequence.
ACCESSION   DAPOXO010000303 DAPOXO010000000
VERSION     DAPOXO010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.308"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT          135 a          118 c           98 g          135 t
ORIGIN      
        1 ggcctacgtg ccaatccggt acctggggcg ctcctaaaat tcaattcaca acgcagacct
       61 acaacatagc taaaaacact cgtaatttaa ggctcggggt ccatgcatat tgctcatgga
      121 cttacctgaa tggctcaccc tttggtggtt ttcaacaggt atattccgac caaaacaacg
      181 tttggtatgt gagtaattat gcttggggaa attatgagtc tggtgggacc atatcagtca
      241 catgcctcaa tcttcctggt gctggagttt aattaaaggg gcaacagtag gcatcgacat
      301 gttcctcatc aacaccatca ccaataccgt acatgcgtgt tccagtcata atgtatccag
      361 tcggacattg aatcggcttg taatagatcg aaccaccact cttaccgccg ataaagtgat
      421 tcattgctac ggatgatttg taccaattac atgctgagta attaatttta ttaccccctg
      481 accacc
//
LOCUS       DAPOXO010000304          474 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.309, whole genome shotgun sequence.
ACCESSION   DAPOXO010000304 DAPOXO010000000
VERSION     DAPOXO010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.309"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..374)
                     /locus_tag="ROH59_005247"
     CDS             complement(<1..374)
                     /locus_tag="ROH59_005247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDX4807591.1"
                     /translation="MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIG"
BASE COUNT          135 a           99 c          101 g          139 t
ORIGIN      
        1 ccaatggtgt tggtgccaac ggcctgacca tttttcggtg caggcgcatg ccacagatcg
       61 gcaaccatgt ttacgcaacg cagatcgatt gctgcagatt gcggatattc ttctttgtcg
      121 atccagtttt tgttaatgga taaatccatc aacttatgga cattttcgtc gtcccaggtc
      181 tggcagaaag tggccaggtt ctgacgagcg ttgccatcaa gatataattc gtcattgata
      241 atctggaatg cgacatcatc acgcatttcg tgcagcggaa aacgttttga ttctgcgata
      301 gtggaaatag acttcgcacc aaaacgtgaa tcgagtagtt ccgaccttaa atccgttact
      361 tgcttcttat ccattttaaa ctccttaaaa tgattggatc gcattaaaaa agtaggattt
      421 atcgataaag taagcaagtg caaaggactc ggttttaaat aacaaaatcc taat
//
LOCUS       DAPOXO010000305          473 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.310, whole genome shotgun sequence.
ACCESSION   DAPOXO010000305 DAPOXO010000000
VERSION     DAPOXO010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.310"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>473
                     /locus_tag="ROH59_005248"
     CDS             <1..>473
                     /locus_tag="ROH59_005248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="kfiB protein"
                     /protein_id="HDX4807592.1"
                     /translation="TKSNEIALLEKYTTLFSLSANETEITFNDTKVSEYLVSELIKER
                     TEVLKLYNELQAYANLPYIETSKDNVSAEAALWEVVEERNSIFNIVSHLVQESKKKDA
                     DIELTKSIFKKRQFLLLNRINELKKEKEEVIKLSKINHNDVVRQEKYPDDIEKKI"
BASE COUNT          201 a           56 c           83 g          133 t
ORIGIN      
        1 tacaaaatca aatgaaattg ccctgcttga aaaatataca actttatttt ctttaagtgc
       61 aaatgagact gaaattacat ttaatgatac aaaggttagt gagtacttag tatctgaatt
      121 aataaaagaa agaaccgagg ttctgaagct ttataatgag ttacaagcct atgcaaacct
      181 accttatata gaaacatcga aagataacgt ttcggctgag gctgcattat gggaggtagt
      241 cgaagagaga aattctatct tcaatattgt atctcatttg gtgcaagagt caaaaaagaa
      301 ggatgcagat attgaattga ctaaatctat atttaagaaa agacaatttt tattattgaa
      361 caggattaat gagctaaaaa aagaaaagga agaggtaatt aaactttcaa aaataaatca
      421 caacgatgtt gtgagacaag aaaaatatcc agatgatatt gaaaaaaaaa taa
//
LOCUS       DAPOXO010000306          458 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.311, whole genome shotgun sequence.
ACCESSION   DAPOXO010000306 DAPOXO010000000
VERSION     DAPOXO010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.311"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>458
                     /locus_tag="ROH59_005249"
     CDS             <1..>458
                     /locus_tag="ROH59_005249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807593.1"
                     /translation="RNLITESEVAVAGNSKFRFVGADAFSPDELRTDLFSDDEGGYVD
                     CVALDAALLEKLQAVAEFLREAEGWEWCAGRMEPVGECREDAGTYRCLPEPEAVLTEA
                     EEERLNELMARYDALENQCEESDLLEAEMKLMRCMAKVRAWTPEMRAGGGV"
BASE COUNT          100 a          108 c          169 g           81 t
ORIGIN      
        1 cgcaatctga ttacggaaag tgaagtggcg gtggcgggga acagtaaatt ccgcttcgtg
       61 ggggctgatg ccttctcgcc agacgaactg cgcaccgatt tgttcagcga cgacgagggt
      121 ggctatgtgg actgcgtggc gctcgatgcc gccctgctgg aaaaactcca ggctgtcgca
      181 gagttccttc gggaagccga aggctgggaa tggtgcgccg gacgcatgga gcctgtcggt
      241 gagtgccgtg aggatgccgg aacataccgc tgtctgccgg agccggaagc ggtgctgacc
      301 gaggcggaag aagaacgtct gaacgaactg atggcacgtt acgacgcgct ggaaaaccag
      361 tgtgaggaat ctgacctgct ggaagcagaa atgaagctga tgcgctgcat ggcgaaggtc
      421 agagcgtgga cgccggagat gcgtgccgga ggtggagt
//
LOCUS       DAPOXO010000307          405 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.312, whole genome shotgun sequence.
ACCESSION   DAPOXO010000307 DAPOXO010000000
VERSION     DAPOXO010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.312"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>405
                     /locus_tag="ROH59_005250"
     CDS             <1..>405
                     /locus_tag="ROH59_005250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="9-O-acetyl-N-acetylneuraminic acid deacetylase"
                     /protein_id="HDX4807594.1"
                     /translation="QSNKAWSLTRPVDDAVSLLTRGGRLSCKFRLSGALTNNQFGLGI
                     YLYTDVALPDVVAMTGTGNPFLMSFFTQTTDGKLNLMHHKKAGNTKLGEFGNYSNDWQ
                     TLELVFTAGSATVTPKLNGVAGPAFQVIKDSLT"
BASE COUNT          101 a          105 c          116 g           83 t
ORIGIN      
        1 cagagcaata aagcctggtc cctgacgcgc ccggtggatg acgcagtctc cctgctgaca
       61 cggggtggca gactgagctg taagtttcga ctgtcaggcg cactgaccaa caatcagttc
      121 ggtctgggaa tttatctgta taccgatgta gcgttacctg acgtcgtggc gatgaccggg
      181 actggtaacc cgttcctgat gtcgttcttc acccagacca cagacggcaa actgaatctg
      241 atgcatcaca agaaagcagg aaacacaaag ttgggcgagt tcgggaatta cagtaacgac
      301 tggcagacgc tggagctggt gttcaccgcc ggcagtgcca cggttactcc gaaactgaat
      361 ggagtggctg gcccggcatt ccaggtcata aaagacagtc tgaca
//
LOCUS       DAPOXO010000308          397 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.313, whole genome shotgun sequence.
ACCESSION   DAPOXO010000308 DAPOXO010000000
VERSION     DAPOXO010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.313"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..389
                     /locus_tag="ROH59_005251"
     CDS             <1..389
                     /locus_tag="ROH59_005251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX4807595.1"
                     /translation="PLLKSLESWLREKMKTLSRHSELAKAFAYALNQWPALTYYADDG
                     WAEADNNIAENALRMVSLGRKNYLFFGSDHGGERGALLYSLIGTCKLNGVEPESYLRY
                     VLDVIADWPINRVGELLPWRVALPTE"
BASE COUNT           97 a          108 c          119 g           73 t
ORIGIN      
        1 aaccgctgct gaaatccctg gaaagctggc tgcgtgaaaa gatgaaaacc ctgtcgcgac
       61 actcagaact ggcgaaagcg ttcgcatacg ccctgaacca gtggccggcg ctgacgtact
      121 atgcagatga tggctgggct gaggcggaca ataacatcgc tgaaaatgcg ttgcggatgg
      181 tcagtctggg ccgcaaaaac tacctgttct tcggttcgga tcatggagga gagcggggag
      241 cgctgctgta cagcctgatc gggacgtgca aactgaacgg agtggagcca gaaagctacc
      301 tccgctatgt ccttgacgtc atagccgact ggccgataaa ccgggtcggc gaactgctcc
      361 cctggcgcgt agcactgccg actgaataac acatccc
//
LOCUS       DAPOXO010000309          391 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.314, whole genome shotgun sequence.
ACCESSION   DAPOXO010000309 DAPOXO010000000
VERSION     DAPOXO010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.314"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            166..>391
                     /locus_tag="ROH59_005252"
     CDS             166..>391
                     /locus_tag="ROH59_005252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000543775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDX4807596.1"
                     /translation="MHDLKYKIYFYTEGEFLEMLEEIVNATSKDKSLKGKKLEKYLDT
                     LVDHFIKITEHPKKGDLIFYPNSQEDGEPEN"
BASE COUNT          148 a           54 c           71 g          118 t
ORIGIN      
        1 agcgcctctt gaaggttggc attatggctc taaggaaatt gttaaagaat tccatatata
       61 tcatagtgtt gcgattgaat gtggtggcga aatttatgat attgataatt aaaggattgt
      121 tacgcctcga ctacatcatg aaattcacta caggagataa tgtatatgca tgatttaaaa
      181 tataaaatat atttttacac agaaggtgaa tttcttgaaa tgcttgagga gatagtaaat
      241 gcaactagca aagataaatc cctaaaaggg aaaaaattag aaaaatatct cgatacctta
      301 gtggatcatt tcattaaaat tactgaacat cctaaaaagg gagatctcat tttctatcct
      361 aattcccaag aagatggtga acctgaaaac a
//
LOCUS       DAPOXO010000310          386 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.315, whole genome shotgun sequence.
ACCESSION   DAPOXO010000310 DAPOXO010000000
VERSION     DAPOXO010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.315"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>386
                     /locus_tag="ROH59_005253"
     CDS             <1..>386
                     /locus_tag="ROH59_005253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDX4807597.1"
                     /translation="VAAGGRRLAALNMLAERGIIPADWPVRVKVIPQELATAASMTEN
                     GHRRDMHPAEQIAGFRAMAQEGKTPAQIGDLLGYSPRHVQRMLKLADLAPVILDALAE
                     DRITTEHCQALALENDTARQVQVFEAA"
BASE COUNT           81 a          114 c          118 g           73 t
ORIGIN      
        1 gtcgccgcag gtggtcgccg actggctgca ctcaacatgc tggcagagcg tggcatcatt
       61 ccggctgact ggcctgtccg tgtgaaggtc attccgcagg agctggcgac ggcggcatca
      121 atgactgaaa acggtcatcg tcgggatatg caccctgctg aacagattgc cggattccgc
      181 gcaatggcgc aggaaggcaa aacacctgca caaatcggtg atttgctggg ctattcaccc
      241 cgccacgttc agcgaatgct gaaactggct gaccttgcgc ctgtcatcct cgatgcgctg
      301 gcagaagacc gcatcaccac cgaacactgt caggcgctgg cgctggagaa cgacaccgcg
      361 cgtcaggtgc aggtgtttga agctgc
//
LOCUS       DAPOXO010000311          375 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.316, whole genome shotgun sequence.
ACCESSION   DAPOXO010000311 DAPOXO010000000
VERSION     DAPOXO010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.316"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            182..>375
                     /locus_tag="ROH59_005254"
     CDS             182..>375
                     /locus_tag="ROH59_005254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001697964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
                     /protein_id="HDX4807598.1"
                     /translation="MIRIEILFDRQSTKNLKSGTLQALQNEIEQRLKPHYPEIWLRID
                     QGSAPSVSVTGARNDKDKER"
BASE COUNT          125 a           90 c           83 g           77 t
ORIGIN      
        1 ttcacagaac cgtgcgcaaa atgctgtgga taagctggac acagcagtcc acagcaggca
       61 tacagccaca ctcccagaga attgagcgtt ttttagtcac aataatgaca tttgactgtg
      121 tgtggattca gttattagaa tactgtatat gcatacagca atagaaaagg gagatgagaa
      181 catgatccgc attgaaattc ttttcgaccg ccagagcaca aaaaacctca aatcaggcac
      241 acttcaggcg ctacagaatg aaatcgaaca acgtctgaaa ccacactacc cggaaatctg
      301 gctgcgtata gaccagggca gcgccccgtc tgtatctgtc acaggagccc gcaacgacaa
      361 ggataaagaa cgtat
//
LOCUS       DAPOXO010000312          368 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.317, whole genome shotgun sequence.
ACCESSION   DAPOXO010000312 DAPOXO010000000
VERSION     DAPOXO010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.317"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..348
                     /locus_tag="ROH59_005255"
     CDS             <1..348
                     /locus_tag="ROH59_005255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDX4807599.1"
                     /translation="HFLGYLNATEMVNFYQDSDIICFPSKLETWGLPLSEAKTYKKWI
                     FAADLPYAHEVLYNYSKTRYFPFDDEKILVRYILEYTSKNMHEDIKNSRVNFNNDALT
                     GFEQFIEYILKGN"
BASE COUNT          131 a           53 c           63 g          121 t
ORIGIN      
        1 catttcctcg gttaccttaa tgcaaccgag atggttaact tttatcaaga ttcagatatt
       61 atttgtttcc catcgaaact agaaacgtgg ggattaccat tatcagaagc taaaacatac
      121 aaaaaatgga tatttgcggc agacttacct tatgctcatg aagttttata taactattca
      181 aaaactagat attttccatt tgacgatgag aaaatacttg ttcgctacat attagagtac
      241 acaagtaaaa atatgcatga agatataaaa aatagtaggg tgaattttaa taatgatgca
      301 ttgactggtt ttgaacagtt tattgaatat atcctcaagg ggaactgacg tggtttatat
      361 tataatcg
//
LOCUS       DAPOXO010000313          358 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.318, whole genome shotgun sequence.
ACCESSION   DAPOXO010000313 DAPOXO010000000
VERSION     DAPOXO010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.318"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            111..>358
                     /gene="bhsA"
                     /locus_tag="ROH59_005256"
     CDS             111..>358
                     /gene="bhsA"
                     /locus_tag="ROH59_005256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HDX4807600.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAV"
BASE COUNT          106 a           79 c           79 g           94 t
ORIGIN      
        1 atgattgtta taaaaaatat cttgtatgtg atccagatca catctatcat ttagttatcg
       61 atcgttaagt aattgcttgc gacgtcattc atctgcataa ggccactatt atgaaaaacg
      121 taaaaaccct catcgctgcg gcgattttaa gctccatgtc atttgccagc tttgcggctg
      181 tcgaagttca gtcaacgcca gaaggccaac aaaaagtcgg tactatcagt gctaacgcgg
      241 ggacaaatct gggatcgctg gaagagcagc tggcgcaaaa agcggatgag atgggcgcaa
      301 aatctttccg tattacttct gtaaccggtc cgaataccct ccatggaaca gcagtaat
//
LOCUS       DAPOXO010000314          344 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.320, whole genome shotgun sequence.
ACCESSION   DAPOXO010000314 DAPOXO010000000
VERSION     DAPOXO010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.320"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>344
                     /locus_tag="ROH59_005257"
     CDS             <1..>344
                     /locus_tag="ROH59_005257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDX4807601.1"
                     /translation="TMATQRGYQMGRWLAGRLMKELGLVSCQQPTYRYKRGGHEHVAI
                     PNYLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPDSRLT
                     MKALEMAWETRG"
BASE COUNT           79 a           86 c          107 g           72 t
ORIGIN      
        1 acaatggcaa cccagagagg ctaccagatg gggcgctggc ttgctggcag actcatgaaa
       61 gagctggggc tggtcagctg tcagcagccg acttaccggt ataaacgtgg tggtcatgaa
      121 catgttgcta tccctaacta ccttgaacgg cagttcgccg tgaccgagcc aaatcaggtg
      181 tggtgcggtg atgtgaccta tatctggacg ggtaagcgct gggcgtacct cgccgttgtt
      241 ctcgacctgt tcgcaagaaa accagtgggc tgggccatgt cgttctcgcc ggacagcagg
      301 cttaccatga aagcactgga aatggcatgg gaaacccgtg gtaa
//
LOCUS       DAPOXO010000315          344 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.321, whole genome shotgun sequence.
ACCESSION   DAPOXO010000315 DAPOXO010000000
VERSION     DAPOXO010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.321"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>344
                     /locus_tag="ROH59_005258"
     CDS             <1..>344
                     /locus_tag="ROH59_005258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDX4807602.1"
                     /translation="GGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVE
                     LREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADT
                     GIDIDMHIDAASG"
BASE COUNT           80 a           97 c          103 g           64 t
ORIGIN      
        1 ggcgggatgg cgatgaaatg gcgttggcgc aagcgtatgg aagccgcagg caaacccacg
       61 gataaaccaa acctggtgtg cggtccggta caaatctgct ggcataaatt cgcccgctac
      121 tgggatgtgg agttgcgtga gatccctatg cgccccggtc agttgtttat ggacccgaaa
      181 cgcatgattg aagcctgcga cgaaaacacc atcggcgtgg tgccgacttt cggcgtgacc
      241 tacaccggta actatgagtt cccgcagccg ctgcacgatg cgctggataa attccaggcc
      301 gacaccggta tcgacatcga catgcacatc gacgccgcca gcgg
//
LOCUS       DAPOXO010000316          342 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.322, whole genome shotgun sequence.
ACCESSION   DAPOXO010000316 DAPOXO010000000
VERSION     DAPOXO010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.322"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..328)
                     /locus_tag="ROH59_005259"
     CDS             complement(<1..328)
                     /locus_tag="ROH59_005259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002948331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2931 family protein"
                     /protein_id="HDX4807603.1"
                     /translation="MSLLAPYDEWYFLFFYPNALPAQVTYVELLDTDGIYYQFRTLDA
                     TAPSSTTIGQWRDNLRVGVLSFNKAKNPPMSIHFCWDSVIDKKVYETWITLAGEVWKL
                     MLTLYSP"
BASE COUNT          101 a           70 c           73 g           98 t
ORIGIN      
        1 gtggtgaata aagtgtgagc atcaatttcc agacttctcc cgccagcgtt atccaggttt
       61 catacacttt tttatcaatc actgaatccc agcagaaatg gatagacata gggggatttt
      121 tggctttatt gaatgataac accccaaccc gaagattatc tctccactga ccaatagtag
      181 tggaactcgg agcggtagca tccagcgttc tgaactgata atagatacca tcagtgtcca
      241 atagttctac ataggtaact tgtgctggta gcgcattagg gtagaaaaaa aggaaatacc
      301 attcatcata gggtgcaagc agtgatattt tttctttcgc tg
//
LOCUS       DAPOXO010000317          337 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.323, whole genome shotgun sequence.
ACCESSION   DAPOXO010000317 DAPOXO010000000
VERSION     DAPOXO010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.323"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..266)
                     /locus_tag="ROH59_005260"
     CDS             complement(<1..266)
                     /locus_tag="ROH59_005260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDX4807604.1"
                     /translation="MFKEKLEDYTEEEFLNFLGGLRSSMKDGKPLKGKELEMYWDSLV
                     DHFIEITQHPSGSDLIFYPKSQGDDKPENILKIVKEWRRSQGLP"
BASE COUNT           94 a           72 c           52 g          119 t
ORIGIN      
        1 aagggtaacc cctgtgaacg ccgccattct ttgacaattt tcaggatgtt ttcaggctta
       61 tcatctcctt gacttttagg gtagaaaatt agatcgctcc ctgacggatg ctgtgtaatt
      121 tcaataaaat gatctactaa tgaatcccag tacatttcta gctccttacc ttttaatggc
      181 tttccatctt tcatagatga tctcaatcca cctaaaaaat taagaaattc ctcctcggta
      241 taatcttcga gcttttcttt aaacatattt atctcctgta gtgaatctca tcgtgtagtc
      301 tgggggtaac aattcgtaaa ttatcaatat cgtatac
//
LOCUS       DAPOXO010000318          336 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.324, whole genome shotgun sequence.
ACCESSION   DAPOXO010000318 DAPOXO010000000
VERSION     DAPOXO010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.324"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            218..>336
                     /locus_tag="ROH59_005261"
     CDS             218..>336
                     /locus_tag="ROH59_005261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707425.1"
                     /note="interacts RssB preventing the degradation of the
                     stress sigma factor RpoS; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HDX4807605.1"
                     /translation="MKWIVIDTVIQPSCGISFSVIWSKIKLIIWYQSDAFLPP"
BASE COUNT          141 a           63 c           43 g           89 t
ORIGIN      
        1 catgtaatac agaaaaaaca caaaaccata ccttaaataa aaacctcatc atcaagcaga
       61 tatgcatgga taaactacaa gacgagatat aaaccaccct gcatttaaat aaacaataaa
      121 caacatcaga aaaataattc tgctctatgg tttacaatca aaaatatcat ttatactttt
      181 cagaacatca ccagcaaggc ataaacaagg aaactaaatg aagtggattg tgattgatac
      241 agttatccag ccatcatgcg gaatatcttt ttcagtcata tggagtaaaa taaaattaat
      301 aatctggtat caatcggatg ctttcttacc tcctga
//
LOCUS       DAPOXO010000319          329 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.325, whole genome shotgun sequence.
ACCESSION   DAPOXO010000319 DAPOXO010000000
VERSION     DAPOXO010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.325"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>329
                     /locus_tag="ROH59_005262"
     CDS             <1..>329
                     /locus_tag="ROH59_005262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDX4807606.1"
                     /translation="DCFENPALAAKIYTKPFPLVDITVVDDNEIMNHRRMAALTLLMK
                     HIRHRDMMELLDKLPQVMVEISDEQVRVLIHYIVNAGDSVSPEFMRALAERLPQHEDK
                     LMTIAERL"
BASE COUNT           81 a           78 c           90 g           80 t
ORIGIN      
        1 gactgttttg agaatccggc gcttgcggct aaaatataca caaagccgtt tccgctggtt
       61 gatatcactg tcgttgatga caatgaaatc atgaaccatc gccggatggc cgcactgacg
      121 ctgctgatga agcatatccg ccatcgtgac atgatggagc tgctggacaa actcccgcag
      181 gtcatggtgg aaatttcaga cgagcaggtg cgtgttctga ttcattacat cgttaacgca
      241 ggggactctg tatcaccgga atttatgcgg gcgctggctg agcgtctgcc gcagcatgag
      301 gataaactga tgactatcgc agaacgtct
//
LOCUS       DAPOXO010000320          325 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.326, whole genome shotgun sequence.
ACCESSION   DAPOXO010000320 DAPOXO010000000
VERSION     DAPOXO010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.326"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>325
                     /locus_tag="ROH59_005263"
     CDS             <1..>325
                     /locus_tag="ROH59_005263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein ImpB"
                     /protein_id="HDX4807607.1"
                     /translation="PAKQQIVCSRSFGERITDKDAMHQAVVQYAERAAEKLRGERQYC
                     RQVTTFVRTSPFAVKEPCYSNAAVEKLPLPTQDSRDIIAAACRALNHVWREGYRYMKA
                     GVMLA"
BASE COUNT           86 a           81 c           92 g           66 t
ORIGIN      
        1 caccggcaaa acagcagatt gtctgtagtc gcagttttgg tgaacgaatc acagacaaag
       61 atgccatgca ccaggctgtt gttcagtatg cagagcgggc cgcagagaaa ctacgtgggg
      121 agcgtcagta ttgccggcag gtgacgacat ttgtacggac atcccccttt gcagtaaaag
      181 aaccctgtta cagcaatgcc gctgtggaaa agcttccatt gcccacacag gacagccggg
      241 acattattgc cgccgcatgc agagccttaa accatgtctg gcgtgaaggg taccgctata
      301 tgaaggcagg agtcatgctg gctga
//
LOCUS       DAPOXO010000321          320 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.327, whole genome shotgun sequence.
ACCESSION   DAPOXO010000321 DAPOXO010000000
VERSION     DAPOXO010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.327"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..309
                     /locus_tag="ROH59_005264"
     CDS             <1..309
                     /locus_tag="ROH59_005264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX4807608.1"
                     /translation="EKPLLHSDQGWHYRIKSYQSALADRGLVQSMSRKGNCLDNAVME
                     NFFGHLKEEMYYRRDYRNVEELENAVNEYITYWNQKRIKLSLGGLSPVEYRTEYQKAG
                     "
BASE COUNT          107 a           65 c           83 g           65 t
ORIGIN      
        1 gagaaaccgc tgctccacag tgatcaagga tggcattacc ggataaaaag ttatcagtcc
       61 gccctggcgg acagagggtt agtgcagagc atgtcgcgca agggcaactg ccttgataat
      121 gcggtaatgg agaacttctt tggtcacctg aaagaagaaa tgtactatcg ccgggactac
      181 agaaatgtag aagagctgga aaatgccgtt aacgaataca taacttactg gaatcaaaaa
      241 agaataaaac tcagtcttgg gggactcagc ccggtagaat accggactga gtatcaaaaa
      301 gccggttaac tgaaactgtc
//
LOCUS       DAPOXO010000322          313 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.328, whole genome shotgun sequence.
ACCESSION   DAPOXO010000322 DAPOXO010000000
VERSION     DAPOXO010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.328"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..>313)
                     /locus_tag="ROH59_005265"
     CDS             complement(<1..>313)
                     /locus_tag="ROH59_005265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDX4807609.1"
                     /translation="AKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRL
                     RGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQ
                     QN"
BASE COUNT           68 a           87 c           89 g           69 t
ORIGIN      
        1 tgttctgctg ggcaataccc tgcagtttcg ggtggtcgct gagatatttc agggaggctt
       61 tgtagtcttc cagcaacagt tcagcaaagt ccatttcgaa gccgcgacga cacataatgc
      121 gcatcaccac gatgtcggtg gcttcaccgc cgagagtgaa ggccggaacc tgccagccgc
      181 gcagacgcag acgttcagag aggtcgtaca gggtgtatcc tggatcttca ccatctttca
      241 gtttgaagca aaccgccggg atgccttcgt ccgggcgacc ggtacagatg aactcatacg
      301 gccccagttt ggc
//
LOCUS       DAPOXO010000323          267 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.329, whole genome shotgun sequence.
ACCESSION   DAPOXO010000323 DAPOXO010000000
VERSION     DAPOXO010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.329"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT           69 a           58 c           75 g           65 t
ORIGIN      
        1 tgaacaaact ttacgatcgc gtgccggctt ccgtctggaa atatgtcacc tgaatcttga
       61 atccgcgcta cgatgactcc ggtgttatct gtgcaccgga agatcgggaa cattaagcag
      121 tataacggca acaaagaatt cgaaatcaaa agggaatggt gtacagaggg gcaggcgttc
      181 aggcattacc ggcctgtatc ttctgaaggg gactcgtatt tgtcggggct gagtattccg
      241 ctcgattcga tcacggattg gcggaat
//
LOCUS       DAPOXO010000324          238 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.331, whole genome shotgun sequence.
ACCESSION   DAPOXO010000324 DAPOXO010000000
VERSION     DAPOXO010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..238
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.331"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>238
                     /locus_tag="ROH59_005266"
     CDS             <1..>238
                     /locus_tag="ROH59_005266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX4807610.1"
                     /translation="YSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGRITEAACW
                     AHARRKIHDVHVRTPSALTEEALKRIGELYAIEAE"
BASE COUNT           55 a           71 c           75 g           37 t
ORIGIN      
        1 tacagcccgg acagaaaagg catccatccg cagacccatc ttgcggggtt cagtggtgta
       61 ctgcaggcgg atgcatacgc cgggttcaac gagctgtacc gggatggccg gataacggaa
      121 gccgcctgtt gggctcacgc ccgccgtaaa atccacgatg tgcacgttcg caccccgtca
      181 gccctgacgg aggaagcgct gaaacggatc ggcgaactgt acgccatcga ggcagaga
//
LOCUS       DAPOXO010000325          238 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.332, whole genome shotgun sequence.
ACCESSION   DAPOXO010000325 DAPOXO010000000
VERSION     DAPOXO010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..238
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.332"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT           87 a           45 c           35 g           71 t
ORIGIN      
        1 ttattaagag atcgaagaat ttgttctggt ggatacgtat aatcaattga taaccgattt
       61 ccatagtgga tacttatatt atcagcacat atgcatttaa caggcccccc tgaaaaaaga
      121 agactgtata aaaaataatt actattatcg caaatcatat aaacatgatt atattgctga
      181 acggcctcat atacagaggc acggccactg aactcaaaac atttatactc ttcatcct
//
LOCUS       DAPOXO010000326          231 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.333, whole genome shotgun sequence.
ACCESSION   DAPOXO010000326 DAPOXO010000000
VERSION     DAPOXO010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.333"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..216
                     /locus_tag="ROH59_005267"
     CDS             <1..216
                     /locus_tag="ROH59_005267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807611.1"
                     /translation="YAGHEKLRADVAEVANTMCDLRARLNDMEHRCRFDSDVLVERLT
                     RQTLYRANRLFMEAYTEILELDSCFKD"
BASE COUNT           55 a           57 c           67 g           52 t
ORIGIN      
        1 tatgccggac acgaaaaact tcgcgccgac gtggcggagg tggccaacac catgtgtgac
       61 cttcgggcca ggctgaacga tatggagcat cgctgtcgct ttgattccga tgtgcttgtt
      121 gaacgcctga cacgccagac gctgtatcgc gccaatcgcc tgtttatgga ggcgtatacc
      181 gaaattctgg aactggattc ctgcttcaaa gattgagaag gagacgagaa t
//
LOCUS       DAPOXO010000327          226 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.334, whole genome shotgun sequence.
ACCESSION   DAPOXO010000327 DAPOXO010000000
VERSION     DAPOXO010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.334"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            48..124
                     /locus_tag="ROH59_005268"
     tRNA            48..124
                     /locus_tag="ROH59_005268"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:82..84,aa:Ile,seq:gat)
BASE COUNT           56 a           50 c           64 g           56 t
ORIGIN      
        1 agtgctcaca cagattgtct gatgaaaatg agcagtaaaa cctctacagg cttgtagctc
       61 aggtggttag agcgcacccc tgataagggt gaggtcggtg gttcaagtcc actcaggcct
      121 accaaatttg caccgcaaat ttgaagaggt tttaactaca tgttatgggg ctatagctca
      181 gctgggagag cgcctgcttt gcacgcagga ggtctgcggt tcgatc
//
LOCUS       DAPOXO010000328          224 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.335, whole genome shotgun sequence.
ACCESSION   DAPOXO010000328 DAPOXO010000000
VERSION     DAPOXO010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..224
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.335"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..>224
                     /locus_tag="ROH59_005269"
     CDS             <1..>224
                     /locus_tag="ROH59_005269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX4807612.1"
                     /translation="IRAQYDDPALRKLHYHIAEVQRMQALIRLKEDIRDERQKLIADG
                     KWYPPSYRQWVEIQAAQGDRAAVSQLRGWD"
BASE COUNT           59 a           47 c           67 g           51 t
ORIGIN      
        1 cattcgtgcg cagtacgatg atccggcatt acgtaagctg cattatcaca ttgcagaagt
       61 tcagcgaatg caggcattga tcaggctgaa agaagacatc agggatgagc gacagaaact
      121 tattgctgac gggaagtggt atccaccctc ttaccgtcag tgggtcgaaa ttcaggctgc
      181 tcagggagac agggctgctg tatcgcagtt gagaggctgg gatt
//
LOCUS       DAPOXO010000329          219 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.336, whole genome shotgun sequence.
ACCESSION   DAPOXO010000329 DAPOXO010000000
VERSION     DAPOXO010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..219
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.336"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
BASE COUNT           47 a           67 c           64 g           41 t
ORIGIN      
        1 ctttttgccg caggcgtcaa aaacttttgc gtctgccccc ggacaactgc cccgtgacgt
       61 ggtgagcgtc ccccgtcgga aaggtccact gcggggaaat ccccgaagac ccggacggca
      121 gaaggagctt cgctcctccg ggaaatgacc tggctgaccc ggcagtcgtg acgatgagga
      181 gacaatgtga tgaatcagac tttacccact gctgacctg
//
LOCUS       DAPOXO010000330          210 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.denovo.338, whole genome shotgun sequence.
ACCESSION   DAPOXO010000330 DAPOXO010000000
VERSION     DAPOXO010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..210
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.denovo.338"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            65..140
                     /locus_tag="ROH59_005270"
     tRNA            65..140
                     /locus_tag="ROH59_005270"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:99..101,aa:Glu,seq:ttc)
BASE COUNT           52 a           52 c           55 g           51 t
ORIGIN      
        1 agtgctcaca cagattgtct gatagaaagt gaaaagcaag gcgtcttgcg aagcagactg
       61 atacgtcccc ttcgtctaga ggcccaggac accgcccttt cacggcggta acaggggttc
      121 gaatccccta ggggacgcca cttgctggtt tgtgagtgaa agtcacctgc cttaatatct
      181 caaaactcat cttcgggtga tgtttgagat
//
LOCUS       DAPOXO010000331         3502 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.guided.196, whole genome shotgun sequence.
ACCESSION   DAPOXO010000331 DAPOXO010000000
VERSION     DAPOXO010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3502
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.guided.196"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            complement(<1..408)
                     /locus_tag="ROH59_005271"
     CDS             complement(<1..408)
                     /locus_tag="ROH59_005271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDX4807613.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGP"
     gene            669..1127
                     /gene="gpt"
                     /locus_tag="ROH59_005272"
     CDS             669..1127
                     /gene="gpt"
                     /locus_tag="ROH59_005272"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDX4807614.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            1219..2463
                     /gene="frsA"
                     /locus_tag="ROH59_005273"
     CDS             1219..2463
                     /gene="frsA"
                     /locus_tag="ROH59_005273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDX4807615.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFSHGAQLPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILEVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     ALRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            2521..2922
                     /gene="crl"
                     /locus_tag="ROH59_005274"
     CDS             2521..2922
                     /gene="crl"
                     /locus_tag="ROH59_005274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDX4807616.1"
                     /translation="MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLRE
                     FHEKLRELLATLNLKLEPADDFRDEPVKLTA"
     gene            complement(2961..>3502)
                     /locus_tag="ROH59_005275"
     CDS             complement(2961..>3502)
                     /locus_tag="ROH59_005275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="porin"
                     /protein_id="HDX4807617.1"
                     /translation="QGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNE
                     QNLQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPISGGFANKTQNFEAVAQY
                     QFDFGLRPSLGYVLSKGKDIEGIGDEDLVNYVDVGATYYFNKNMSAFVDYKINQLDSD
                     NKLNLNNDDIVAVGMTYQF"
BASE COUNT          858 a          841 c          899 g          904 t
ORIGIN      
        1 cgggccgtga accacgtttt cgtcagccag aaccgccagt gcggaggcca taccaatgcc
       61 gttatccgca cccagcgtgg tgccgcgcgc tttaacccat tcgccatcaa tataaggctg
      121 gataggatct ttagtgaagt catgcacggt gtcgttattt ttttgcggca ccatatcgag
      181 gtgggcctgc aagacgaccg gtttacgatt ttccatacct gcggtagcag gtttacgaat
      241 caggatatta cctacctgat cgcgttcgac atggaaacct ttctcttttg cccaaccaac
      301 aatgtattca gcgagttgct cttcatgata ggacgggtga ggaatagaac agattttggc
      361 aaaaatatcc cacagcggct gtggagataa ttgagacagt tcagacacgt taagtctcct
      421 tgtcgatcac ccgcaaaaca gtattgcagg tcacagggtt agcagaaaat gttgtcaaca
      481 caagacaggc ttgcgagata tgtttgagaa taccacttta tcccgcgtca gggagaggca
      541 gtgcgtaaaa agacgcggac tcatgtgaaa tactggtttt tagtgcgcca gatctctata
      601 atctcgcgca acctattttc ccctcgaaca ctttttaagc cgtagataaa caggctggga
      661 cacttcacat gagcgaaaaa tacatcgtca cctgggacat gttgcagatc catgcacgta
      721 aactcgcaag ccgactgatg ccttctgaac aatggaaagg cattattgcc gtaagccgtg
      781 gcggtctggt accgggtgcg ttactggcgc gtgaactggg tattcgtcat gtcgataccg
      841 tttgtatttc cagctacgat cacgacaacc agcgcgagct taaagtgctg aaacgcgcag
      901 aaggcgatgg cgaaggcttc atcgttattg atgacctggt agataccggt ggtactgcgg
      961 ttgcgattcg tgaaatgtat ccaaaagcgc actttgtcac catcttcgca aaaccggctg
     1021 gtcgtccgct ggttgatgat tatgttgttg atatcccgca aaatacctgg atcgaacagc
     1081 cgtgggatat gggcgtcgta ttcgtcccgc caatctccgg tcgctaatct tttcaacgcc
     1141 tggcactgcc gggcgttgtt ctttttaact tcaggcgggt tacaatagtt tccagtaagt
     1201 attctggagg ctgcatctat gacacaggca aacctgagcg aaaccctgtt caaaccccgc
     1261 tttaaacatc ctgaaacctc gacgctagtc cgccgcttta gtcacggcgc acaactgcct
     1321 gtgcagtcgg cccttgatgg taaaaccatc cctcactggt atcgcatgat taaccgtctg
     1381 atgtggatct ggcgcggcat tgacccccgt gaaatcctcg aagtccaggc gcgtattgtg
     1441 atgagcgatg ccgaacgtac cgacgatgat ttatacgata cggtgattgg ctaccgcggc
     1501 ggcaactgga tttatgagtg ggctacccag gcgatggtgt ggcaacaaaa agcctgtgcg
     1561 gaagaagatc cgcaactcag cggtcgacac tggctgcatg cggctacgtt gtacaacatt
     1621 gctgcctatc ctcatctgaa aggagatgac ctggccgagc aagcgcaggc tttgtcaaac
     1681 cgcgcctatg aagaggccgc tcagcgtctg ccgggcacga tgcggcagat ggagtttacc
     1741 gtacccggcg gtgcgcccat caccggcttt ttgcatatgc cgaaaggcga tggcccgttc
     1801 ccgacagtat taatgtgtgg tggtctggat gcgatgcaga cagactatta cagcctgtat
     1861 gaacgttatt ttgcgctgcg cggcattgcg atgctgacta ttgatatgcc gtcggtgggc
     1921 ttttcttcaa aatggaagct cacccaggac tccagcctgt tgcatcagca cgttttaaag
     1981 gcgttgccta acgtaccgtg ggtggatcac actcgcgtcg cggcctttgg tttccgtttc
     2041 ggcgctaacg ttgccgtacg tctggcatac cttgaatcgc cgcgtctgaa agcggttgcc
     2101 tgtcttggtc cggtagttca taccctgttg agtgatttta agtgccagca acaggtgccg
     2161 gaaatgtatc ttgacgttct ggcgagtcgt ttggggatgc atgatgcttc tgacgaagcg
     2221 ttgcgcgtgg agctgaatcg ctattcatta aaagtgcaag ggttgctggg acgtcgctgc
     2281 ccaacgccaa tgttatcagg ctactggaag aacgatccgt tcagcccgga agaggactca
     2341 cgcttaatca cgtcgtcatc tgctgacggt aaattattag agatcccatt taacccggtg
     2401 tatcggaatt ttgacaaagg ccttcaggaa atcacagact ggatcgaaaa acgtttgtgt
     2461 taaaaatttg ctaaatttta ccaatttggt aaaacagttg catcacaaca ggagattgca
     2521 atgacgttac cgagtggaca cccgaagagc agattagtca aaaaatttac cgcactaggc
     2581 ccgtatattc gtgaaggtaa gtgcgaagat aatcgattct ttttcgattg tctggctgta
     2641 tgcgtcaacg tgaaaccggc accggaagtg cgtgagttct ggggctggtg gatggaactg
     2701 gaagcgcagg aatcccgttt tacctacagt taccagtttg gtctgttcga taaagcaggc
     2761 gactggacga gtgttcagat aaaagatgcc gaagtggttg aacgactgga gcacaccctg
     2821 cgtgaatttc acgagaagct gcgtgagctg ctggcgacgc tgaatctgaa gctggaaccg
     2881 gcagatgatt ttcgtgatga accggtgaag ttaacggcgt gaatgaaatg tgccggatgc
     2941 atcacatccg gcaatatcca ttaaaactga taggtcatgc caaccgcgac aatatcatca
     3001 ttattaagat tcaatttgtt atcgctatcc agttggttga ttttataatc aacaaacgct
     3061 gacatatttt tgttgaaata atacgtagca ccaacatcga cataattgac cagatcttca
     3121 tcaccgatgc cctcaatatc tttccctttc gataagacat aacccagcga tggacgcaga
     3181 ccaaagtcaa actggtattg agcgaccgct tcaaagttct gcgtcttatt ggcaaagccg
     3241 ccagagattg gcgtcatttt acgtgtttca gaatagaaag ttgccagata aatattattg
     3301 gcatcgtatt tcagacctgt tgcccatgct tctgcacgct tgcctgtgcc acggctttgc
     3361 aggttctgct cgttggtgcg atcagagttg gtataggctc cactgatggc gaaatcgctg
     3421 ccaccaaagt catatgtcaa tgacgtgccg aagccatcgc cgttttgctt tttaacgtcg
     3481 cggttttcgt ttttcccttg at
//
LOCUS       DAPOXO010000332         3326 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.guided.199, whole genome shotgun sequence.
ACCESSION   DAPOXO010000332 DAPOXO010000000
VERSION     DAPOXO010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3326
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.guided.199"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            166..1311
                     /locus_tag="ROH59_005276"
     CDS             166..1311
                     /locus_tag="ROH59_005276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C beta-lactamase CMY-2"
                     /protein_id="HDX4807618.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQA
                     IPGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGE
                     IKLSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQP
                     QWTPGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKD
                     YAWGYREGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQ
                     SRYWRIGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVH
                     KTGSTGGFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
     gene            1405..1938
                     /locus_tag="ROH59_005277"
     CDS             1405..1938
                     /locus_tag="ROH59_005277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HDX4807619.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIAT
                     REGFEVNKLIWVKQPGA"
     gene            complement(1935..2252)
                     /gene="sugE"
                     /locus_tag="ROH59_005278"
     CDS             complement(1935..2252)
                     /gene="sugE"
                     /locus_tag="ROH59_005278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDX4807620.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIA
                     MLSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKL
                     STH"
     gene            2481..3230
                     /locus_tag="ROH59_005279"
                     /pseudo
     CDS             2481..3230
                     /locus_tag="ROH59_005279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426061.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein finQ"
BASE COUNT          942 a          809 c          800 g          775 t
ORIGIN      
        1 gtgaaatagt gatttttgaa gctaataaaa aacacacgtg gaatttagga aaaacttata
       61 tctgctgcta aatttaaccg tttgtcaaca cggtgcaaat caaacacact gattgcgtct
      121 gacgggcccg gacacctttt tgcttttaat tacggaactg atttcatgat gaaaaaatcg
      181 ttatgctgcg ctctgctgct gacagcctct ttctccacat ttgctgccgc aaaaacagaa
      241 caacagattg ccgatatcgt taatcgcacc atcaccccgt tgatgcagga gcaggctatt
      301 ccgggtatgg ccgttgccgt tatctaccag ggaaaaccct attatttcac ctggggtaaa
      361 gccgatatcg ccaataacca cccagtcacg cagcaaacgc tgtttgagct aggatcggtt
      421 agtaagacgt ttaacggcgt gttgggcggc gatgctatcg cccgcggcga aattaagctc
      481 agcgatccgg tcacgaaata ctggccagaa ctgacaggca aacagtggca gggtatccgc
      541 ctgctgcact tagccaccta tacggcaggc ggcctaccgc tgcagatccc cgatgacgtt
      601 agggataaag ccgcattact gcatttttat caaaactggc agccgcaatg gactccgggc
      661 gctaagcgac tttacgctaa ctccagcatt ggtctgtttg gcgcgctggc ggtgaaaccc
      721 tcaggaatga gttacgaaga ggcaatgacc agacgcgtcc tgcaaccatt aaaactggcg
      781 catacctgga ttacggttcc gcagaacgaa caaaaagatt atgcctgggg ctatcgcgaa
      841 gggaagcccg tacacgtttc tccgggacaa cttgacgccg aagcctatgg cgtgaaatcc
      901 agcgttattg atatggcccg ctgggttcag gccaacatgg atgccagcca cgttcaggag
      961 aaaacgctcc agcagggcat tgcgcttgcg cagtctcgct actggcgtat tggcgatatg
     1021 taccagggat taggctggga gatgctgaac tggccgctga aagctgattc gatcatcaac
     1081 ggcagcgaca gcaaagtggc attggcagcg cttcccgccg ttgaggtaaa cccgcccgcc
     1141 cccgcagtga aagcctcatg ggtgcataaa acgggctcca ctggtggatt tggcagctac
     1201 gtagccttcg ttccagaaaa aaaccttggc atcgtgatgc tggcaaacaa aagctatcct
     1261 aaccctgtcc gtgtcgaggc ggcctggcgc attcttgaaa agctgcaata actgacgatg
     1321 aggcccagga tattgggcct cctttctttc tctttttttc ctgttgtcat ctacacttaa
     1381 caaaaataca gcaaggaaaa tcccatgcgc attttgcccg tcgttgctgc agttacggct
     1441 gcattcctgg ttgtcgcgtg tagctccccg acaccgccga aaggcgttac cgtggtaaat
     1501 aactttgatg ccaaacgcta tctgggaacc tggtatgaaa ttgcgcgctt cgaccatcgt
     1561 ttcgagcgcg gattggataa agtgaccgca acatacagct tgcgcgacga cggcggcatc
     1621 aacgttatta acaagggcta taaccctgac agggagatgt ggcagaaaac ggaagggaaa
     1681 gcctatttca ccggcgaccc aagcagagcc gcgcttaagg tttctttttt cggccccttc
     1741 tatggcgggt ataacgtaat tgcactcgac cgggaatatc gtcacgcgct ggtttgtggt
     1801 ccggatcgcg actacctgtg gatcctttca cggaccccta ctatttcaga tgaaatgaaa
     1861 cagcaaatgt tagccatcgc gacccgggaa gggtttgaag tgaataaact gatttgggtg
     1921 aaacagcctg gcgcttagtg agtgctcagc ttcagaccaa taatgccagc aacgatcagc
     1981 ccaaggctca gcaaacgtgc cgggctggca gactcaccca gcagcaaaat ccctgtaatg
     2041 gccgccccaa cagcgccaat accggtccag accgcataag cggttcctac aggcaacgtg
     2101 cgcattgccc aagagagcat ggcgatactg acgatcatcg ccgcaatagt gataatgctt
     2161 ggcgtaagac gcgtaaaacc gtgggtgtat ttcaggccaa tcgcccagac aacttcgagc
     2221 aaacctgcaa ttaataaaac gatccaggac atatcaggct ccagaacaat ggggccgtcc
     2281 ccggtgaaag aagcgtttgc aggtcgtcct gcaaagctaa tgtgtgaaat ggcatttttg
     2341 cccggaagaa aatgaatttc aaccttttta ttcaccgcct gctaaaagca agaattaagc
     2401 ataattagcg gcgtagttcc cgcatttggc actcatcgga gttctctatg atgaagggct
     2461 ttctgaaacc agaaagtcga gataacattc ctgcacagat cctcaaggaa ctcccttcat
     2521 ggagtatcta tgtttcagcc gaaaatctgc atactatact tcctacgtcc tatccgatac
     2581 atggattttt cttttatcca tttttggaca ataatggaaa tattatccgg cttttcatta
     2641 ttgatgatct gaaacaaagt caaggaacta cagggctaaa agaaaagaat gttgacgtcg
     2701 tcaataatat catcagaata aaggactctc gtgaaggact tcttgactcc agaaagatgg
     2761 agtgtatcga tggtgaagtc gtcgtaacag ttaacgaaaa gctcaaagat ttcagagaca
     2821 gggagtttaa tcttcttaac gcacagatat caatggtgct ttatatctgt tcacagatca
     2881 atgatataaa agaaaaaaat caatttaaac ggtcagaaaa gcacaaaaag catgttcaca
     2941 ctcaccatga actaccagca caaaacattc gggagtggga cgttggtatt cgaatggggc
     3001 aagccatacg gcaatatcgc caagcagaac ccacagggaa agagcggaca acaataggta
     3061 gcaaacgtcc tcatatacgc cggggacact ggcatacata ctggacagga agtaagaaac
     3121 cagaactagc ccatgagcgt aaacctagat taatatggtt acctccggta ccagttaatt
     3181 tagaagacgt aaacaaacta ccggtggtaa taacgcccat tgataaatga cctgagaagt
     3241 atcttttccg gtaggatgta cacatatcta aattatcagg ctactgtaat gttgttcatg
     3301 cattacagta gagcccttgg ttgatt
//
LOCUS       DAPOXO010000333         2051 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.guided.225, whole genome shotgun sequence.
ACCESSION   DAPOXO010000333 DAPOXO010000000
VERSION     DAPOXO010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2051
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.guided.225"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..291
                     /gene="frdC"
                     /locus_tag="ROH59_005280"
     CDS             <1..291
                     /gene="frdC"
                     /locus_tag="ROH59_005280"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDX4807621.1"
                     /translation="AVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAA
                     ALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            302..661
                     /gene="frdD"
                     /locus_tag="ROH59_005281"
     CDS             302..661
                     /gene="frdD"
                     /locus_tag="ROH59_005281"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDX4807622.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            724..1857
                     /locus_tag="ROH59_005282"
     CDS             724..1857
                     /locus_tag="ROH59_005282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDX4807623.1"
                     /translation="MFKTTLCTLLITASCSTFAAPQQINDIVHRTITPLIEQQRIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMKTRVFQPLKLNHTWINVPSAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKILQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDIIINGSDNKIALAARPVKPITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNTLQ"
BASE COUNT          505 a          524 c          512 g          510 t
ORIGIN      
        1 gctgtgtggt tcagcattga actgattttc gggctgtttg ccctgaaaaa tggcccggaa
       61 gcctgggcgg gattcgtcga ctttttacaa aacccggtta tcgtgatcat taacctgatc
      121 actctggcgg cagccctact gcacaccaaa acctggtttg agctggcacc aaaagcggcc
      181 aatatcattg taaaagacga aaaaatggga ccagagccaa ttatcaaaag tctctgggcg
      241 gtaactgtgg ttgccaccat cgtaatcctg tttgttgccc tgtactggta aggagcctga
      301 gatgattaat ccaaatccaa agcgttctga tgaaccggta ttctggggcc tcttcggggc
      361 cggtggtatg tggagcgcca tcattgcgcc ggtgatgatc ctactggttg gtattctgct
      421 accgctaggg ctgtttccag gtgatgcgct gagctacgag cgcgttctgg cgttcgcgca
      481 gagcttcatt ggtcgcgtat tcctgttcct gatgatcgtt ctgccgctgt ggtgtggttt
      541 acaccgaatg caccacgcga tgcacgatct gaaaatccac gtacctgcgg gtaaatgggt
      601 tttctacggt ctggctgcta tcctgacagt tgtcacactg attggtgtcg ttacaatcta
      661 acgcatcgcc aatgtaaatc cggcccgcct atggcgggcc gttttgtatg gaaaccagac
      721 cctatgttca aaacgacgct ctgcacctta ttaattaccg cctcttgctc cacatttgcc
      781 gcccctcaac aaatcaacga tattgtgcat cgcacaatta ccccgcttat agagcaacaa
      841 aggatccccg gtatggcggt agcggtaatt tatcagggta aaccttatta ctttacctgg
      901 ggctatgcgg acatcgccaa aaagcagccc gtcacacagc aaacgttgtt tgagttaggt
      961 tcggtcagca aaacatttac gggcgtgctt ggtggcgacg ctattgctcg aggggaaatc
     1021 aagttaagcg atcccacaac aaaatactgg cctgaactta ccgctaaaca gtggaatggg
     1081 atcacactat tacatctcgc aacctacacc gctggcggcc tgccattgca ggtgccggat
     1141 gaggtgaaat cctcaagcga cttgctgcgc ttctatcaaa actggcagcc tgcatgggct
     1201 ccaggaacac aacgtctgta tgccaactcc agtatcggtt tgttcggcgc actggctgtg
     1261 aagccgtctg gtttgagttt tgagcaggcg atgaaaactc gtgtcttcca gccactcaaa
     1321 ctcaatcata cgtggattaa tgtaccgtcc gcagaagaaa agaactacgc ctggggatat
     1381 cgcgaaggta aggcagtaca tgtttcgcca ggggcgttag atgctgaagc ttatggtgtg
     1441 aagtcgacca ttgaagatat ggcccgctgg gtgcaaagca atttaaaacc ccttgatatc
     1501 aatgagaaaa tacttcaaca agggatacaa ctggcacaat ctcgctactg gcaaaccggc
     1561 gatatgtatc agggtctggg ctgggaaatg ctggactggc cggtaaatcc tgacatcatc
     1621 attaacggca gtgacaataa aattgcactg gcagcacgcc ccgtaaaacc gattacgccc
     1681 ccaactcctg cagtacgcgc atcatgggta cataaaacgg gggcgaccgg cggatttggt
     1741 agctatgtcg cgtttattcc agaaaaagag ctgggtatcg tgatgctggc taacaaaaac
     1801 tatcccaatc cagcgagagt taccgccgcc tggcagattc tcaacactct acagtaaaat
     1861 ttcatcgggt ccgaattttc ggaccttttc tccgcttttc cttgctgtca tctacactta
     1921 gaaaaaaacc agtaaggaaa catttatgcg cctgctccct ctcgttgccg cagcgacagc
     1981 tgcatttctg gtcgttgcct gcagttctcc tacaccgccg cgtggcgtga ccgtagtgaa
     2041 taatttcgac g
//
LOCUS       DAPOXO010000334         2051 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.guided.226, whole genome shotgun sequence.
ACCESSION   DAPOXO010000334 DAPOXO010000000
VERSION     DAPOXO010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2051
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.guided.226"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            <1..291
                     /gene="frdC"
                     /locus_tag="ROH59_005283"
     CDS             <1..291
                     /gene="frdC"
                     /locus_tag="ROH59_005283"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDX4807624.1"
                     /translation="AVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAA
                     ALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            302..661
                     /gene="frdD"
                     /locus_tag="ROH59_005284"
     CDS             302..661
                     /gene="frdD"
                     /locus_tag="ROH59_005284"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDX4807625.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            724..1857
                     /locus_tag="ROH59_005285"
     CDS             724..1857
                     /locus_tag="ROH59_005285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDX4807626.1"
                     /translation="MFKTTLCTLLITASCSTFAAPQQINDIVHRTITPLIEQQRIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMKTRVFQPLKLNHTWINVPSAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKILQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDIIINGSDNKIALAARPVKPITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNTLQ"
BASE COUNT          504 a          524 c          513 g          510 t
ORIGIN      
        1 gctgtgtggt tcagcattga actgattttc gggctgtttg ccctgaaaaa tggcccggaa
       61 gcctgggcgg gattcgtcga ctttttacaa aacccggtta tcgtgatcat taacctgatc
      121 actctggcgg cagccctact gcacaccaaa acctggtttg agctggcacc aaaagcggcc
      181 aatatcattg taaaagacga aaaaatggga ccagagccaa ttatcaaaag tctctgggcg
      241 gtaactgtgg ttgccaccat cgtaatcctg tttgttgccc tgtactggta aggagcctga
      301 gatgattaat ccaaatccaa agcgttctga tgaaccggta ttctggggcc tcttcggggc
      361 cggtggtatg tggagcgcca tcattgcgcc ggtgatgatc ctactggttg gtattctgct
      421 accgctaggg ctgtttccag gtgatgcgct gagctacgag cgcgttctgg cgttcgcgca
      481 gagcttcatt ggtcgcgtat tcctgttcct gatgatcgtt ctgccgctgt ggtgtggttt
      541 acaccgaatg caccacgcga tgcacgatct gaaaatccac gtacctgcgg gtaaatgggt
      601 tttctacggt ctggctgcta tcctgacagt tgtcacactg attggtgtcg ttacaatcta
      661 acgcatcgcc aatgtaaatc cggcccgcct atggcgggcc gttttgtatg gaaaccagac
      721 cctatgttca aaacgacgct ctgcacctta ttaattaccg cctcttgctc cacatttgcc
      781 gcccctcaac aaatcaacga tattgtgcat cgcacaatta ccccgcttat agagcaacaa
      841 aggatccccg gtatggcggt agcggtaatt tatcagggta aaccttatta ctttacctgg
      901 ggctatgcgg acatcgccaa aaagcagccc gtcacacagc aaacgttgtt tgagttaggt
      961 tcggtcagca aaacatttac gggcgtgctt ggtggcgacg ctattgctcg aggggaaatc
     1021 aagttaagcg atcccacaac aaaatactgg cctgaactta ccgctaaaca gtggaatggg
     1081 atcacactat tacatctcgc aacctacacc gctggcggcc tgccattgca ggtgccggat
     1141 gaggtgaaat cctcaagcga cttgctgcgc ttctatcaaa actggcagcc tgcatgggct
     1201 ccaggaacac aacgtctgta tgccaactcc agtatcggtt tgttcggcgc actggctgtg
     1261 aagccgtctg gtttgagttt tgagcaggcg atgaaaactc gtgtcttcca gccactcaaa
     1321 ctcaatcata cgtggattaa tgtaccgtcc gcagaagaaa agaactacgc ctggggatat
     1381 cgcgaaggta aggcagtaca tgtttcgcca ggggcgttag atgctgaagc ttatggtgtg
     1441 aagtcgacca ttgaagatat ggcccgctgg gtgcagagca atttaaaacc ccttgatatc
     1501 aatgagaaaa tacttcaaca agggatacaa ctggcacaat ctcgctactg gcaaaccggc
     1561 gatatgtatc agggtctggg ctgggaaatg ctggactggc cggtaaatcc tgacatcatc
     1621 attaacggca gtgacaataa aattgcactg gcagcacgcc ccgtaaaacc gattacgccc
     1681 ccaactcctg cagtacgcgc atcatgggta cataaaacgg gggcgaccgg cggatttggt
     1741 agctatgtcg cgtttattcc agaaaaagag ctgggtatcg tgatgctggc taacaaaaac
     1801 tatcccaatc cagcgagagt taccgccgcc tggcagattc tcaacactct acagtaaaat
     1861 ttcatcgggt ccgaattttc ggaccttttc tccgcttttc cttgctgtca tctacactta
     1921 gaaaaaaacc agtaaggaaa catttatgcg cctgctccct ctcgttgccg cagcgacagc
     1981 tgcatttctg gtcgttgcct gcagttctcc tacaccgccg cgtggcgtga ccgtagtgaa
     2041 taatttcgac g
//
LOCUS       DAPOXO010000335         1005 bp    DNA     linear   BCT 21-SEP-2023
DEFINITION  TPA_asm: Escherichia coli strain JBBBAEF-19-0054
            SAMD00498243-rid17773103.guided.265, whole genome shotgun sequence.
ACCESSION   DAPOXO010000335 DAPOXO010000000
VERSION     DAPOXO010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00498243
            Sequence Read Archive: DRR386747
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-APR-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001702215.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001702215.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/26/2023 01:01:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,286
            CDSs (total)                      :: 5,207
            Genes (coding)                    :: 5,075
            CDSs (with protein)               :: 5,075
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 56 of 132
            Pseudo Genes (incomplete)         :: 80 of 132
            Pseudo Genes (internal stop)      :: 30 of 132
            Pseudo Genes (multiple problems)  :: 30 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00498243-rid17773103.guided.265"
                     /strain="JBBBAEF-19-0054"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Japan: Saitama"
                     /lat_lon="35.857315 N 139.648722 E"
                     /collection_date="2019-11-19"
                     /collected_by="AMRRC, NIID"
     gene            18..818
                     /gene="bla"
                     /locus_tag="ROH59_005286"
     CDS             18..818
                     /gene="bla"
                     /locus_tag="ROH59_005286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032699754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase"
                     /protein_id="HDX4807627.1"
                     /translation="MANFATVPVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERF
                     PMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCS
                     AAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
                     PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGER
                     GSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW"
BASE COUNT          273 a          228 c          252 g          252 t
ORIGIN      
        1 agacaaaagg ctgcctcatc gctaactttg caacagtgcc ggtgaaagta aaagatgctg
       61 aagatcagtt gggtgcacga gtgggttaca tcgaactgga tctcaacagc ggtaagatcc
      121 ttgagagttt tcgccccgaa gaacgttttc caatgatgag cacttttaaa gttctgctat
      181 gtggtgcggt attatcccgt gttgacgccg ggcaagagca actcggtcgc cgcatacact
      241 attctcagaa tgacttggtt gagtactcac cagtcacaga aaagcatctt acggatggca
      301 tgacagtaag agaattatgc agtgctgcca taaccatgag tgataacact gctgccaact
      361 tacttctgac aacgatcgga ggaccgaagg agctaaccgc ttttttgcac aacatggggg
      421 atcatgtaac tcgccttgat cgttgggaac cggagctgaa tgaagccata ccaaacgacg
      481 agcgtgacac cacgatgcct gcagcaatgg caacaacgtt gcgcaaacta ttaactggcg
      541 aactacttac tctagcttcc cggcaacaat taatagactg gatggaggcg gataaagttg
      601 caggaccact tctgcgctcg gcccttccgg ctggctggtt tattgctgat aaatctggag
      661 ccggtgagcg tgggtctcgc ggtatcattg cagcactggg gccagatggt aagccctccc
      721 gtatcgtagt tatctacacg acggggagtc aggcaactat ggatgaacga aatagacaga
      781 tcgctgagat aggtgcctca ctgattaagc attggtaact gtcagaccaa gtttactcat
      841 atatacttta gattgattta aaacttcatt tttaatttaa aaggatctag gtgaagatcc
      901 tttttgataa tctcatgacc aaaatccctt aacgtgagtt ttcgttccac tgagcgtcag
      961 acccctgaga gcagagatag cgctgatgtc cggcggtgct tttgc
//
